data_8YX2
# 
_entry.id   8YX2 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8YX2         pdb_00008yx2 10.2210/pdb8yx2/pdb 
WWPDB D_1300046506 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8YX2 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              shang_jinsai@gzlab.ac.cn 
_pdbx_contact_author.name_first         Jinsai 
_pdbx_contact_author.name_last          Shang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8164-1544 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lu, Y.'    1 0000-0002-9985-8546 
'Shang, J.' 2 0000-0001-8164-1544 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                10169 
_citation.page_last                 10169 
_citation.title                     
'Discovery of orally bioavailable SARS-CoV-2 papain-like protease inhibitor as a potential treatment for COVID-19.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-54462-0 
_citation.pdbx_database_id_PubMed   39580525 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lu, Y.'      1  0000-0002-9985-8546 
primary 'Yang, Q.'    2  0009-0009-1648-4189 
primary 'Ran, T.'     3  0000-0002-1387-4634 
primary 'Zhang, G.'   4  ?                   
primary 'Li, W.'      5  ?                   
primary 'Zhou, P.'    6  ?                   
primary 'Tang, J.'    7  ?                   
primary 'Dai, M.'     8  ?                   
primary 'Zhong, J.'   9  ?                   
primary 'Chen, H.'    10 ?                   
primary 'He, P.'      11 ?                   
primary 'Zhou, A.'    12 ?                   
primary 'Xue, B.'     13 ?                   
primary 'Chen, J.'    14 ?                   
primary 'Zhang, J.'   15 ?                   
primary 'Yang, S.'    16 ?                   
primary 'Wu, K.'      17 ?                   
primary 'Wu, X.'      18 ?                   
primary 'Tang, M.'    19 ?                   
primary 'Zhang, W.K.' 20 0000-0003-4960-6137 
primary 'Guo, D.'     21 0000-0002-8297-0814 
primary 'Chen, X.'    22 0000-0002-4052-8155 
primary 'Chen, H.'    23 0000-0002-8065-8333 
primary 'Shang, J.'   24 0000-0001-8164-1544 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Papain-like protease nsp3'                                                                        35712.484 2   
3.4.19.12,3.4.22.- C111S ? ? 
2 non-polymer syn 'ZINC ION'                                                                                         65.409    4   
?                  ?     ? ? 
3 non-polymer syn '~{N}-[1-(1,2-dihydroacenaphthylen-5-yl)cyclopropyl]-2-methyl-5-(4-methylpiperazin-1-yl)benzamide' 425.565   2   
?                  ?     ? ? 
4 water       nat water                                                                                              18.015    185 
?                  ?     ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSF
LGRYMSALNHTKKWKYPQVNGLTSIKWADNNSYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV
GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQES
PFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSF
LGRYMSALNHTKKWKYPQVNGLTSIKWADNNSYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV
GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQES
PFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK
;
_entity_poly.pdbx_strand_id                 B,A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'ZINC ION'                                                                                         ZN    
3 '~{N}-[1-(1,2-dihydroacenaphthylen-5-yl)cyclopropyl]-2-methyl-5-(4-methylpiperazin-1-yl)benzamide' A1LZ5 
4 water                                                                                              HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   GLU n 
1 3   VAL n 
1 4   ARG n 
1 5   THR n 
1 6   ILE n 
1 7   LYS n 
1 8   VAL n 
1 9   PHE n 
1 10  THR n 
1 11  THR n 
1 12  VAL n 
1 13  ASP n 
1 14  ASN n 
1 15  ILE n 
1 16  ASN n 
1 17  LEU n 
1 18  HIS n 
1 19  THR n 
1 20  GLN n 
1 21  VAL n 
1 22  VAL n 
1 23  ASP n 
1 24  MET n 
1 25  SER n 
1 26  MET n 
1 27  THR n 
1 28  TYR n 
1 29  GLY n 
1 30  GLN n 
1 31  GLN n 
1 32  PHE n 
1 33  GLY n 
1 34  PRO n 
1 35  THR n 
1 36  TYR n 
1 37  LEU n 
1 38  ASP n 
1 39  GLY n 
1 40  ALA n 
1 41  ASP n 
1 42  VAL n 
1 43  THR n 
1 44  LYS n 
1 45  ILE n 
1 46  LYS n 
1 47  PRO n 
1 48  HIS n 
1 49  ASN n 
1 50  SER n 
1 51  HIS n 
1 52  GLU n 
1 53  GLY n 
1 54  LYS n 
1 55  THR n 
1 56  PHE n 
1 57  TYR n 
1 58  VAL n 
1 59  LEU n 
1 60  PRO n 
1 61  ASN n 
1 62  ASP n 
1 63  ASP n 
1 64  THR n 
1 65  LEU n 
1 66  ARG n 
1 67  VAL n 
1 68  GLU n 
1 69  ALA n 
1 70  PHE n 
1 71  GLU n 
1 72  TYR n 
1 73  TYR n 
1 74  HIS n 
1 75  THR n 
1 76  THR n 
1 77  ASP n 
1 78  PRO n 
1 79  SER n 
1 80  PHE n 
1 81  LEU n 
1 82  GLY n 
1 83  ARG n 
1 84  TYR n 
1 85  MET n 
1 86  SER n 
1 87  ALA n 
1 88  LEU n 
1 89  ASN n 
1 90  HIS n 
1 91  THR n 
1 92  LYS n 
1 93  LYS n 
1 94  TRP n 
1 95  LYS n 
1 96  TYR n 
1 97  PRO n 
1 98  GLN n 
1 99  VAL n 
1 100 ASN n 
1 101 GLY n 
1 102 LEU n 
1 103 THR n 
1 104 SER n 
1 105 ILE n 
1 106 LYS n 
1 107 TRP n 
1 108 ALA n 
1 109 ASP n 
1 110 ASN n 
1 111 ASN n 
1 112 SER n 
1 113 TYR n 
1 114 LEU n 
1 115 ALA n 
1 116 THR n 
1 117 ALA n 
1 118 LEU n 
1 119 LEU n 
1 120 THR n 
1 121 LEU n 
1 122 GLN n 
1 123 GLN n 
1 124 ILE n 
1 125 GLU n 
1 126 LEU n 
1 127 LYS n 
1 128 PHE n 
1 129 ASN n 
1 130 PRO n 
1 131 PRO n 
1 132 ALA n 
1 133 LEU n 
1 134 GLN n 
1 135 ASP n 
1 136 ALA n 
1 137 TYR n 
1 138 TYR n 
1 139 ARG n 
1 140 ALA n 
1 141 ARG n 
1 142 ALA n 
1 143 GLY n 
1 144 GLU n 
1 145 ALA n 
1 146 ALA n 
1 147 ASN n 
1 148 PHE n 
1 149 CYS n 
1 150 ALA n 
1 151 LEU n 
1 152 ILE n 
1 153 LEU n 
1 154 ALA n 
1 155 TYR n 
1 156 CYS n 
1 157 ASN n 
1 158 LYS n 
1 159 THR n 
1 160 VAL n 
1 161 GLY n 
1 162 GLU n 
1 163 LEU n 
1 164 GLY n 
1 165 ASP n 
1 166 VAL n 
1 167 ARG n 
1 168 GLU n 
1 169 THR n 
1 170 MET n 
1 171 SER n 
1 172 TYR n 
1 173 LEU n 
1 174 PHE n 
1 175 GLN n 
1 176 HIS n 
1 177 ALA n 
1 178 ASN n 
1 179 LEU n 
1 180 ASP n 
1 181 SER n 
1 182 CYS n 
1 183 LYS n 
1 184 ARG n 
1 185 VAL n 
1 186 LEU n 
1 187 ASN n 
1 188 VAL n 
1 189 VAL n 
1 190 CYS n 
1 191 LYS n 
1 192 THR n 
1 193 CYS n 
1 194 GLY n 
1 195 GLN n 
1 196 GLN n 
1 197 GLN n 
1 198 THR n 
1 199 THR n 
1 200 LEU n 
1 201 LYS n 
1 202 GLY n 
1 203 VAL n 
1 204 GLU n 
1 205 ALA n 
1 206 VAL n 
1 207 MET n 
1 208 TYR n 
1 209 MET n 
1 210 GLY n 
1 211 THR n 
1 212 LEU n 
1 213 SER n 
1 214 TYR n 
1 215 GLU n 
1 216 GLN n 
1 217 PHE n 
1 218 LYS n 
1 219 LYS n 
1 220 GLY n 
1 221 VAL n 
1 222 GLN n 
1 223 ILE n 
1 224 PRO n 
1 225 CYS n 
1 226 THR n 
1 227 CYS n 
1 228 GLY n 
1 229 LYS n 
1 230 GLN n 
1 231 ALA n 
1 232 THR n 
1 233 LYS n 
1 234 TYR n 
1 235 LEU n 
1 236 VAL n 
1 237 GLN n 
1 238 GLN n 
1 239 GLU n 
1 240 SER n 
1 241 PRO n 
1 242 PHE n 
1 243 VAL n 
1 244 MET n 
1 245 MET n 
1 246 SER n 
1 247 ALA n 
1 248 PRO n 
1 249 PRO n 
1 250 ALA n 
1 251 GLN n 
1 252 TYR n 
1 253 GLU n 
1 254 LEU n 
1 255 LYS n 
1 256 HIS n 
1 257 GLY n 
1 258 THR n 
1 259 PHE n 
1 260 THR n 
1 261 CYS n 
1 262 ALA n 
1 263 SER n 
1 264 GLU n 
1 265 TYR n 
1 266 THR n 
1 267 GLY n 
1 268 ASN n 
1 269 TYR n 
1 270 GLN n 
1 271 CYS n 
1 272 GLY n 
1 273 HIS n 
1 274 TYR n 
1 275 LYS n 
1 276 HIS n 
1 277 ILE n 
1 278 THR n 
1 279 SER n 
1 280 LYS n 
1 281 GLU n 
1 282 THR n 
1 283 LEU n 
1 284 TYR n 
1 285 CYS n 
1 286 ILE n 
1 287 ASP n 
1 288 GLY n 
1 289 ALA n 
1 290 LEU n 
1 291 LEU n 
1 292 THR n 
1 293 LYS n 
1 294 SER n 
1 295 SER n 
1 296 GLU n 
1 297 TYR n 
1 298 LYS n 
1 299 GLY n 
1 300 PRO n 
1 301 ILE n 
1 302 THR n 
1 303 ASP n 
1 304 VAL n 
1 305 PHE n 
1 306 TYR n 
1 307 LYS n 
1 308 GLU n 
1 309 ASN n 
1 310 SER n 
1 311 TYR n 
1 312 THR n 
1 313 THR n 
1 314 THR n 
1 315 ILE n 
1 316 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   316 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'rep, 1a-1b' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Severe acute respiratory syndrome coronavirus 2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2697049 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1LZ5 non-polymer         . '~{N}-[1-(1,2-dihydroacenaphthylen-5-yl)cyclopropyl]-2-methyl-5-(4-methylpiperazin-1-yl)benzamide' ? 
'C28 H31 N3 O'   425.565 
ALA   'L-peptide linking' y ALANINE                                                                                            ? 
'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                                                                                           ? 
'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE                                                                                         ? 
'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                                                                    ? 
'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE                                                                                           ? 
'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE                                                                                          ? 
'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                                                                    ? 
'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                                                                                            ? 
'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE                                                                                          ? 
'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                                                                                              ? 
'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE                                                                                         ? 
'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                                                                                            ? 
'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                                                                                             ? 
'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE                                                                                         ? 
'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                                                                      ? 
'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                                                                                            ? 
'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                                                                                             ? 
'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE                                                                                          ? 
'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                                                                         ? 
'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                                                                                           ? 
'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                                                                                             ? 
'C5 H11 N O2'    117.146 
ZN    non-polymer         . 'ZINC ION'                                                                                         ? 
'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   0   ?   ?   ?   B . n 
A 1 2   GLU 2   1   1   GLU GLU B . n 
A 1 3   VAL 3   2   2   VAL VAL B . n 
A 1 4   ARG 4   3   3   ARG ARG B . n 
A 1 5   THR 5   4   4   THR THR B . n 
A 1 6   ILE 6   5   5   ILE ILE B . n 
A 1 7   LYS 7   6   6   LYS LYS B . n 
A 1 8   VAL 8   7   7   VAL VAL B . n 
A 1 9   PHE 9   8   8   PHE PHE B . n 
A 1 10  THR 10  9   9   THR THR B . n 
A 1 11  THR 11  10  10  THR THR B . n 
A 1 12  VAL 12  11  11  VAL VAL B . n 
A 1 13  ASP 13  12  12  ASP ASP B . n 
A 1 14  ASN 14  13  13  ASN ASN B . n 
A 1 15  ILE 15  14  14  ILE ILE B . n 
A 1 16  ASN 16  15  15  ASN ASN B . n 
A 1 17  LEU 17  16  16  LEU LEU B . n 
A 1 18  HIS 18  17  17  HIS HIS B . n 
A 1 19  THR 19  18  18  THR THR B . n 
A 1 20  GLN 20  19  19  GLN GLN B . n 
A 1 21  VAL 21  20  20  VAL VAL B . n 
A 1 22  VAL 22  21  21  VAL VAL B . n 
A 1 23  ASP 23  22  22  ASP ASP B . n 
A 1 24  MET 24  23  23  MET MET B . n 
A 1 25  SER 25  24  24  SER SER B . n 
A 1 26  MET 26  25  25  MET MET B . n 
A 1 27  THR 27  26  26  THR THR B . n 
A 1 28  TYR 28  27  27  TYR TYR B . n 
A 1 29  GLY 29  28  28  GLY GLY B . n 
A 1 30  GLN 30  29  29  GLN GLN B . n 
A 1 31  GLN 31  30  30  GLN GLN B . n 
A 1 32  PHE 32  31  31  PHE PHE B . n 
A 1 33  GLY 33  32  32  GLY GLY B . n 
A 1 34  PRO 34  33  33  PRO PRO B . n 
A 1 35  THR 35  34  34  THR THR B . n 
A 1 36  TYR 36  35  35  TYR TYR B . n 
A 1 37  LEU 37  36  36  LEU LEU B . n 
A 1 38  ASP 38  37  37  ASP ASP B . n 
A 1 39  GLY 39  38  38  GLY GLY B . n 
A 1 40  ALA 40  39  39  ALA ALA B . n 
A 1 41  ASP 41  40  40  ASP ASP B . n 
A 1 42  VAL 42  41  41  VAL VAL B . n 
A 1 43  THR 43  42  42  THR THR B . n 
A 1 44  LYS 44  43  43  LYS LYS B . n 
A 1 45  ILE 45  44  44  ILE ILE B . n 
A 1 46  LYS 46  45  45  LYS LYS B . n 
A 1 47  PRO 47  46  46  PRO PRO B . n 
A 1 48  HIS 48  47  47  HIS HIS B . n 
A 1 49  ASN 49  48  48  ASN ASN B . n 
A 1 50  SER 50  49  49  SER SER B . n 
A 1 51  HIS 51  50  50  HIS HIS B . n 
A 1 52  GLU 52  51  51  GLU GLU B . n 
A 1 53  GLY 53  52  52  GLY GLY B . n 
A 1 54  LYS 54  53  53  LYS LYS B . n 
A 1 55  THR 55  54  54  THR THR B . n 
A 1 56  PHE 56  55  55  PHE PHE B . n 
A 1 57  TYR 57  56  56  TYR TYR B . n 
A 1 58  VAL 58  57  57  VAL VAL B . n 
A 1 59  LEU 59  58  58  LEU LEU B . n 
A 1 60  PRO 60  59  59  PRO PRO B . n 
A 1 61  ASN 61  60  60  ASN ASN B . n 
A 1 62  ASP 62  61  61  ASP ASP B . n 
A 1 63  ASP 63  62  62  ASP ASP B . n 
A 1 64  THR 64  63  63  THR THR B . n 
A 1 65  LEU 65  64  64  LEU LEU B . n 
A 1 66  ARG 66  65  65  ARG ARG B . n 
A 1 67  VAL 67  66  66  VAL VAL B . n 
A 1 68  GLU 68  67  67  GLU GLU B . n 
A 1 69  ALA 69  68  68  ALA ALA B . n 
A 1 70  PHE 70  69  69  PHE PHE B . n 
A 1 71  GLU 71  70  70  GLU GLU B . n 
A 1 72  TYR 72  71  71  TYR TYR B . n 
A 1 73  TYR 73  72  72  TYR TYR B . n 
A 1 74  HIS 74  73  73  HIS HIS B . n 
A 1 75  THR 75  74  74  THR THR B . n 
A 1 76  THR 76  75  75  THR THR B . n 
A 1 77  ASP 77  76  76  ASP ASP B . n 
A 1 78  PRO 78  77  77  PRO PRO B . n 
A 1 79  SER 79  78  78  SER SER B . n 
A 1 80  PHE 80  79  79  PHE PHE B . n 
A 1 81  LEU 81  80  80  LEU LEU B . n 
A 1 82  GLY 82  81  81  GLY GLY B . n 
A 1 83  ARG 83  82  82  ARG ARG B . n 
A 1 84  TYR 84  83  83  TYR TYR B . n 
A 1 85  MET 85  84  84  MET MET B . n 
A 1 86  SER 86  85  85  SER SER B . n 
A 1 87  ALA 87  86  86  ALA ALA B . n 
A 1 88  LEU 88  87  87  LEU LEU B . n 
A 1 89  ASN 89  88  88  ASN ASN B . n 
A 1 90  HIS 90  89  89  HIS HIS B . n 
A 1 91  THR 91  90  90  THR THR B . n 
A 1 92  LYS 92  91  91  LYS LYS B . n 
A 1 93  LYS 93  92  92  LYS LYS B . n 
A 1 94  TRP 94  93  93  TRP TRP B . n 
A 1 95  LYS 95  94  94  LYS LYS B . n 
A 1 96  TYR 96  95  95  TYR TYR B . n 
A 1 97  PRO 97  96  96  PRO PRO B . n 
A 1 98  GLN 98  97  97  GLN GLN B . n 
A 1 99  VAL 99  98  98  VAL VAL B . n 
A 1 100 ASN 100 99  99  ASN ASN B . n 
A 1 101 GLY 101 100 100 GLY GLY B . n 
A 1 102 LEU 102 101 101 LEU LEU B . n 
A 1 103 THR 103 102 102 THR THR B . n 
A 1 104 SER 104 103 103 SER SER B . n 
A 1 105 ILE 105 104 104 ILE ILE B . n 
A 1 106 LYS 106 105 105 LYS LYS B . n 
A 1 107 TRP 107 106 106 TRP TRP B . n 
A 1 108 ALA 108 107 107 ALA ALA B . n 
A 1 109 ASP 109 108 108 ASP ASP B . n 
A 1 110 ASN 110 109 109 ASN ASN B . n 
A 1 111 ASN 111 110 110 ASN ASN B . n 
A 1 112 SER 112 111 111 SER SER B . n 
A 1 113 TYR 113 112 112 TYR TYR B . n 
A 1 114 LEU 114 113 113 LEU LEU B . n 
A 1 115 ALA 115 114 114 ALA ALA B . n 
A 1 116 THR 116 115 115 THR THR B . n 
A 1 117 ALA 117 116 116 ALA ALA B . n 
A 1 118 LEU 118 117 117 LEU LEU B . n 
A 1 119 LEU 119 118 118 LEU LEU B . n 
A 1 120 THR 120 119 119 THR THR B . n 
A 1 121 LEU 121 120 120 LEU LEU B . n 
A 1 122 GLN 122 121 121 GLN GLN B . n 
A 1 123 GLN 123 122 122 GLN GLN B . n 
A 1 124 ILE 124 123 123 ILE ILE B . n 
A 1 125 GLU 125 124 124 GLU GLU B . n 
A 1 126 LEU 126 125 125 LEU LEU B . n 
A 1 127 LYS 127 126 126 LYS LYS B . n 
A 1 128 PHE 128 127 127 PHE PHE B . n 
A 1 129 ASN 129 128 128 ASN ASN B . n 
A 1 130 PRO 130 129 129 PRO PRO B . n 
A 1 131 PRO 131 130 130 PRO PRO B . n 
A 1 132 ALA 132 131 131 ALA ALA B . n 
A 1 133 LEU 133 132 132 LEU LEU B . n 
A 1 134 GLN 134 133 133 GLN GLN B . n 
A 1 135 ASP 135 134 134 ASP ASP B . n 
A 1 136 ALA 136 135 135 ALA ALA B . n 
A 1 137 TYR 137 136 136 TYR TYR B . n 
A 1 138 TYR 138 137 137 TYR TYR B . n 
A 1 139 ARG 139 138 138 ARG ARG B . n 
A 1 140 ALA 140 139 139 ALA ALA B . n 
A 1 141 ARG 141 140 140 ARG ARG B . n 
A 1 142 ALA 142 141 141 ALA ALA B . n 
A 1 143 GLY 143 142 142 GLY GLY B . n 
A 1 144 GLU 144 143 143 GLU GLU B . n 
A 1 145 ALA 145 144 144 ALA ALA B . n 
A 1 146 ALA 146 145 145 ALA ALA B . n 
A 1 147 ASN 147 146 146 ASN ASN B . n 
A 1 148 PHE 148 147 147 PHE PHE B . n 
A 1 149 CYS 149 148 148 CYS CYS B . n 
A 1 150 ALA 150 149 149 ALA ALA B . n 
A 1 151 LEU 151 150 150 LEU LEU B . n 
A 1 152 ILE 152 151 151 ILE ILE B . n 
A 1 153 LEU 153 152 152 LEU LEU B . n 
A 1 154 ALA 154 153 153 ALA ALA B . n 
A 1 155 TYR 155 154 154 TYR TYR B . n 
A 1 156 CYS 156 155 155 CYS CYS B . n 
A 1 157 ASN 157 156 156 ASN ASN B . n 
A 1 158 LYS 158 157 157 LYS LYS B . n 
A 1 159 THR 159 158 158 THR THR B . n 
A 1 160 VAL 160 159 159 VAL VAL B . n 
A 1 161 GLY 161 160 160 GLY GLY B . n 
A 1 162 GLU 162 161 161 GLU GLU B . n 
A 1 163 LEU 163 162 162 LEU LEU B . n 
A 1 164 GLY 164 163 163 GLY GLY B . n 
A 1 165 ASP 165 164 164 ASP ASP B . n 
A 1 166 VAL 166 165 165 VAL VAL B . n 
A 1 167 ARG 167 166 166 ARG ARG B . n 
A 1 168 GLU 168 167 167 GLU GLU B . n 
A 1 169 THR 169 168 168 THR THR B . n 
A 1 170 MET 170 169 169 MET MET B . n 
A 1 171 SER 171 170 170 SER SER B . n 
A 1 172 TYR 172 171 171 TYR TYR B . n 
A 1 173 LEU 173 172 172 LEU LEU B . n 
A 1 174 PHE 174 173 173 PHE PHE B . n 
A 1 175 GLN 175 174 174 GLN GLN B . n 
A 1 176 HIS 176 175 175 HIS HIS B . n 
A 1 177 ALA 177 176 176 ALA ALA B . n 
A 1 178 ASN 178 177 177 ASN ASN B . n 
A 1 179 LEU 179 178 178 LEU LEU B . n 
A 1 180 ASP 180 179 179 ASP ASP B . n 
A 1 181 SER 181 180 180 SER SER B . n 
A 1 182 CYS 182 181 181 CYS CYS B . n 
A 1 183 LYS 183 182 182 LYS LYS B . n 
A 1 184 ARG 184 183 183 ARG ARG B . n 
A 1 185 VAL 185 184 184 VAL VAL B . n 
A 1 186 LEU 186 185 185 LEU LEU B . n 
A 1 187 ASN 187 186 186 ASN ASN B . n 
A 1 188 VAL 188 187 187 VAL VAL B . n 
A 1 189 VAL 189 188 188 VAL VAL B . n 
A 1 190 CYS 190 189 189 CYS CYS B . n 
A 1 191 LYS 191 190 190 LYS LYS B . n 
A 1 192 THR 192 191 191 THR THR B . n 
A 1 193 CYS 193 192 192 CYS CYS B . n 
A 1 194 GLY 194 193 193 GLY GLY B . n 
A 1 195 GLN 195 194 194 GLN GLN B . n 
A 1 196 GLN 196 195 195 GLN GLN B . n 
A 1 197 GLN 197 196 196 GLN GLN B . n 
A 1 198 THR 198 197 197 THR THR B . n 
A 1 199 THR 199 198 198 THR THR B . n 
A 1 200 LEU 200 199 199 LEU LEU B . n 
A 1 201 LYS 201 200 200 LYS LYS B . n 
A 1 202 GLY 202 201 201 GLY GLY B . n 
A 1 203 VAL 203 202 202 VAL VAL B . n 
A 1 204 GLU 204 203 203 GLU GLU B . n 
A 1 205 ALA 205 204 204 ALA ALA B . n 
A 1 206 VAL 206 205 205 VAL VAL B . n 
A 1 207 MET 207 206 206 MET MET B . n 
A 1 208 TYR 208 207 207 TYR TYR B . n 
A 1 209 MET 209 208 208 MET MET B . n 
A 1 210 GLY 210 209 209 GLY GLY B . n 
A 1 211 THR 211 210 210 THR THR B . n 
A 1 212 LEU 212 211 211 LEU LEU B . n 
A 1 213 SER 213 212 212 SER SER B . n 
A 1 214 TYR 214 213 213 TYR TYR B . n 
A 1 215 GLU 215 214 214 GLU GLU B . n 
A 1 216 GLN 216 215 215 GLN GLN B . n 
A 1 217 PHE 217 216 216 PHE PHE B . n 
A 1 218 LYS 218 217 217 LYS LYS B . n 
A 1 219 LYS 219 218 218 LYS LYS B . n 
A 1 220 GLY 220 219 219 GLY GLY B . n 
A 1 221 VAL 221 220 220 VAL VAL B . n 
A 1 222 GLN 222 221 221 GLN GLN B . n 
A 1 223 ILE 223 222 222 ILE ILE B . n 
A 1 224 PRO 224 223 223 PRO PRO B . n 
A 1 225 CYS 225 224 ?   ?   ?   B . n 
A 1 226 THR 226 225 225 THR THR B . n 
A 1 227 CYS 227 226 226 CYS CYS B . n 
A 1 228 GLY 228 227 227 GLY GLY B . n 
A 1 229 LYS 229 228 228 LYS LYS B . n 
A 1 230 GLN 230 229 229 GLN GLN B . n 
A 1 231 ALA 231 230 230 ALA ALA B . n 
A 1 232 THR 232 231 231 THR THR B . n 
A 1 233 LYS 233 232 232 LYS LYS B . n 
A 1 234 TYR 234 233 233 TYR TYR B . n 
A 1 235 LEU 235 234 234 LEU LEU B . n 
A 1 236 VAL 236 235 235 VAL VAL B . n 
A 1 237 GLN 237 236 236 GLN GLN B . n 
A 1 238 GLN 238 237 237 GLN GLN B . n 
A 1 239 GLU 239 238 238 GLU GLU B . n 
A 1 240 SER 240 239 239 SER SER B . n 
A 1 241 PRO 241 240 240 PRO PRO B . n 
A 1 242 PHE 242 241 241 PHE PHE B . n 
A 1 243 VAL 243 242 242 VAL VAL B . n 
A 1 244 MET 244 243 243 MET MET B . n 
A 1 245 MET 245 244 244 MET MET B . n 
A 1 246 SER 246 245 245 SER SER B . n 
A 1 247 ALA 247 246 246 ALA ALA B . n 
A 1 248 PRO 248 247 247 PRO PRO B . n 
A 1 249 PRO 249 248 248 PRO PRO B . n 
A 1 250 ALA 250 249 249 ALA ALA B . n 
A 1 251 GLN 251 250 250 GLN GLN B . n 
A 1 252 TYR 252 251 251 TYR TYR B . n 
A 1 253 GLU 253 252 252 GLU GLU B . n 
A 1 254 LEU 254 253 253 LEU LEU B . n 
A 1 255 LYS 255 254 254 LYS LYS B . n 
A 1 256 HIS 256 255 255 HIS HIS B . n 
A 1 257 GLY 257 256 256 GLY GLY B . n 
A 1 258 THR 258 257 257 THR THR B . n 
A 1 259 PHE 259 258 258 PHE PHE B . n 
A 1 260 THR 260 259 259 THR THR B . n 
A 1 261 CYS 261 260 260 CYS CYS B . n 
A 1 262 ALA 262 261 261 ALA ALA B . n 
A 1 263 SER 263 262 262 SER SER B . n 
A 1 264 GLU 264 263 263 GLU GLU B . n 
A 1 265 TYR 265 264 264 TYR TYR B . n 
A 1 266 THR 266 265 265 THR THR B . n 
A 1 267 GLY 267 266 266 GLY GLY B . n 
A 1 268 ASN 268 267 267 ASN ASN B . n 
A 1 269 TYR 269 268 268 TYR TYR B . n 
A 1 270 GLN 270 269 269 GLN GLN B . n 
A 1 271 CYS 271 270 270 CYS CYS B . n 
A 1 272 GLY 272 271 271 GLY GLY B . n 
A 1 273 HIS 273 272 272 HIS HIS B . n 
A 1 274 TYR 274 273 273 TYR TYR B . n 
A 1 275 LYS 275 274 274 LYS LYS B . n 
A 1 276 HIS 276 275 275 HIS HIS B . n 
A 1 277 ILE 277 276 276 ILE ILE B . n 
A 1 278 THR 278 277 277 THR THR B . n 
A 1 279 SER 279 278 278 SER SER B . n 
A 1 280 LYS 280 279 279 LYS LYS B . n 
A 1 281 GLU 281 280 280 GLU GLU B . n 
A 1 282 THR 282 281 281 THR THR B . n 
A 1 283 LEU 283 282 282 LEU LEU B . n 
A 1 284 TYR 284 283 283 TYR TYR B . n 
A 1 285 CYS 285 284 284 CYS CYS B . n 
A 1 286 ILE 286 285 285 ILE ILE B . n 
A 1 287 ASP 287 286 286 ASP ASP B . n 
A 1 288 GLY 288 287 287 GLY GLY B . n 
A 1 289 ALA 289 288 288 ALA ALA B . n 
A 1 290 LEU 290 289 289 LEU LEU B . n 
A 1 291 LEU 291 290 290 LEU LEU B . n 
A 1 292 THR 292 291 291 THR THR B . n 
A 1 293 LYS 293 292 292 LYS LYS B . n 
A 1 294 SER 294 293 293 SER SER B . n 
A 1 295 SER 295 294 294 SER SER B . n 
A 1 296 GLU 296 295 295 GLU GLU B . n 
A 1 297 TYR 297 296 296 TYR TYR B . n 
A 1 298 LYS 298 297 297 LYS LYS B . n 
A 1 299 GLY 299 298 298 GLY GLY B . n 
A 1 300 PRO 300 299 299 PRO PRO B . n 
A 1 301 ILE 301 300 300 ILE ILE B . n 
A 1 302 THR 302 301 301 THR THR B . n 
A 1 303 ASP 303 302 302 ASP ASP B . n 
A 1 304 VAL 304 303 303 VAL VAL B . n 
A 1 305 PHE 305 304 304 PHE PHE B . n 
A 1 306 TYR 306 305 305 TYR TYR B . n 
A 1 307 LYS 307 306 306 LYS LYS B . n 
A 1 308 GLU 308 307 307 GLU GLU B . n 
A 1 309 ASN 309 308 308 ASN ASN B . n 
A 1 310 SER 310 309 309 SER SER B . n 
A 1 311 TYR 311 310 310 TYR TYR B . n 
A 1 312 THR 312 311 311 THR THR B . n 
A 1 313 THR 313 312 312 THR THR B . n 
A 1 314 THR 314 313 313 THR THR B . n 
A 1 315 ILE 315 314 314 ILE ILE B . n 
A 1 316 LYS 316 315 ?   ?   ?   B . n 
B 1 1   GLY 1   0   ?   ?   ?   A . n 
B 1 2   GLU 2   1   1   GLU GLU A . n 
B 1 3   VAL 3   2   2   VAL VAL A . n 
B 1 4   ARG 4   3   3   ARG ARG A . n 
B 1 5   THR 5   4   4   THR THR A . n 
B 1 6   ILE 6   5   5   ILE ILE A . n 
B 1 7   LYS 7   6   6   LYS LYS A . n 
B 1 8   VAL 8   7   7   VAL VAL A . n 
B 1 9   PHE 9   8   8   PHE PHE A . n 
B 1 10  THR 10  9   9   THR THR A . n 
B 1 11  THR 11  10  10  THR THR A . n 
B 1 12  VAL 12  11  11  VAL VAL A . n 
B 1 13  ASP 13  12  12  ASP ASP A . n 
B 1 14  ASN 14  13  13  ASN ASN A . n 
B 1 15  ILE 15  14  14  ILE ILE A . n 
B 1 16  ASN 16  15  15  ASN ASN A . n 
B 1 17  LEU 17  16  16  LEU LEU A . n 
B 1 18  HIS 18  17  17  HIS HIS A . n 
B 1 19  THR 19  18  18  THR THR A . n 
B 1 20  GLN 20  19  19  GLN GLN A . n 
B 1 21  VAL 21  20  20  VAL VAL A . n 
B 1 22  VAL 22  21  21  VAL VAL A . n 
B 1 23  ASP 23  22  22  ASP ASP A . n 
B 1 24  MET 24  23  23  MET MET A . n 
B 1 25  SER 25  24  24  SER SER A . n 
B 1 26  MET 26  25  25  MET MET A . n 
B 1 27  THR 27  26  26  THR THR A . n 
B 1 28  TYR 28  27  27  TYR TYR A . n 
B 1 29  GLY 29  28  28  GLY GLY A . n 
B 1 30  GLN 30  29  29  GLN GLN A . n 
B 1 31  GLN 31  30  30  GLN GLN A . n 
B 1 32  PHE 32  31  31  PHE PHE A . n 
B 1 33  GLY 33  32  32  GLY GLY A . n 
B 1 34  PRO 34  33  33  PRO PRO A . n 
B 1 35  THR 35  34  34  THR THR A . n 
B 1 36  TYR 36  35  35  TYR TYR A . n 
B 1 37  LEU 37  36  36  LEU LEU A . n 
B 1 38  ASP 38  37  37  ASP ASP A . n 
B 1 39  GLY 39  38  38  GLY GLY A . n 
B 1 40  ALA 40  39  39  ALA ALA A . n 
B 1 41  ASP 41  40  40  ASP ASP A . n 
B 1 42  VAL 42  41  41  VAL VAL A . n 
B 1 43  THR 43  42  42  THR THR A . n 
B 1 44  LYS 44  43  43  LYS LYS A . n 
B 1 45  ILE 45  44  44  ILE ILE A . n 
B 1 46  LYS 46  45  45  LYS LYS A . n 
B 1 47  PRO 47  46  46  PRO PRO A . n 
B 1 48  HIS 48  47  47  HIS HIS A . n 
B 1 49  ASN 49  48  48  ASN ASN A . n 
B 1 50  SER 50  49  49  SER SER A . n 
B 1 51  HIS 51  50  50  HIS HIS A . n 
B 1 52  GLU 52  51  51  GLU GLU A . n 
B 1 53  GLY 53  52  52  GLY GLY A . n 
B 1 54  LYS 54  53  53  LYS LYS A . n 
B 1 55  THR 55  54  54  THR THR A . n 
B 1 56  PHE 56  55  55  PHE PHE A . n 
B 1 57  TYR 57  56  56  TYR TYR A . n 
B 1 58  VAL 58  57  57  VAL VAL A . n 
B 1 59  LEU 59  58  58  LEU LEU A . n 
B 1 60  PRO 60  59  59  PRO PRO A . n 
B 1 61  ASN 61  60  60  ASN ASN A . n 
B 1 62  ASP 62  61  61  ASP ASP A . n 
B 1 63  ASP 63  62  62  ASP ASP A . n 
B 1 64  THR 64  63  63  THR THR A . n 
B 1 65  LEU 65  64  64  LEU LEU A . n 
B 1 66  ARG 66  65  65  ARG ARG A . n 
B 1 67  VAL 67  66  66  VAL VAL A . n 
B 1 68  GLU 68  67  67  GLU GLU A . n 
B 1 69  ALA 69  68  68  ALA ALA A . n 
B 1 70  PHE 70  69  69  PHE PHE A . n 
B 1 71  GLU 71  70  70  GLU GLU A . n 
B 1 72  TYR 72  71  71  TYR TYR A . n 
B 1 73  TYR 73  72  72  TYR TYR A . n 
B 1 74  HIS 74  73  73  HIS HIS A . n 
B 1 75  THR 75  74  74  THR THR A . n 
B 1 76  THR 76  75  75  THR THR A . n 
B 1 77  ASP 77  76  76  ASP ASP A . n 
B 1 78  PRO 78  77  77  PRO PRO A . n 
B 1 79  SER 79  78  78  SER SER A . n 
B 1 80  PHE 80  79  79  PHE PHE A . n 
B 1 81  LEU 81  80  80  LEU LEU A . n 
B 1 82  GLY 82  81  81  GLY GLY A . n 
B 1 83  ARG 83  82  82  ARG ARG A . n 
B 1 84  TYR 84  83  83  TYR TYR A . n 
B 1 85  MET 85  84  84  MET MET A . n 
B 1 86  SER 86  85  85  SER SER A . n 
B 1 87  ALA 87  86  86  ALA ALA A . n 
B 1 88  LEU 88  87  87  LEU LEU A . n 
B 1 89  ASN 89  88  88  ASN ASN A . n 
B 1 90  HIS 90  89  89  HIS HIS A . n 
B 1 91  THR 91  90  90  THR THR A . n 
B 1 92  LYS 92  91  91  LYS LYS A . n 
B 1 93  LYS 93  92  92  LYS LYS A . n 
B 1 94  TRP 94  93  93  TRP TRP A . n 
B 1 95  LYS 95  94  94  LYS LYS A . n 
B 1 96  TYR 96  95  95  TYR TYR A . n 
B 1 97  PRO 97  96  96  PRO PRO A . n 
B 1 98  GLN 98  97  97  GLN GLN A . n 
B 1 99  VAL 99  98  98  VAL VAL A . n 
B 1 100 ASN 100 99  99  ASN ASN A . n 
B 1 101 GLY 101 100 100 GLY GLY A . n 
B 1 102 LEU 102 101 101 LEU LEU A . n 
B 1 103 THR 103 102 102 THR THR A . n 
B 1 104 SER 104 103 103 SER SER A . n 
B 1 105 ILE 105 104 104 ILE ILE A . n 
B 1 106 LYS 106 105 105 LYS LYS A . n 
B 1 107 TRP 107 106 106 TRP TRP A . n 
B 1 108 ALA 108 107 107 ALA ALA A . n 
B 1 109 ASP 109 108 108 ASP ASP A . n 
B 1 110 ASN 110 109 109 ASN ASN A . n 
B 1 111 ASN 111 110 110 ASN ASN A . n 
B 1 112 SER 112 111 111 SER SER A . n 
B 1 113 TYR 113 112 112 TYR TYR A . n 
B 1 114 LEU 114 113 113 LEU LEU A . n 
B 1 115 ALA 115 114 114 ALA ALA A . n 
B 1 116 THR 116 115 115 THR THR A . n 
B 1 117 ALA 117 116 116 ALA ALA A . n 
B 1 118 LEU 118 117 117 LEU LEU A . n 
B 1 119 LEU 119 118 118 LEU LEU A . n 
B 1 120 THR 120 119 119 THR THR A . n 
B 1 121 LEU 121 120 120 LEU LEU A . n 
B 1 122 GLN 122 121 121 GLN GLN A . n 
B 1 123 GLN 123 122 122 GLN GLN A . n 
B 1 124 ILE 124 123 123 ILE ILE A . n 
B 1 125 GLU 125 124 124 GLU GLU A . n 
B 1 126 LEU 126 125 125 LEU LEU A . n 
B 1 127 LYS 127 126 126 LYS LYS A . n 
B 1 128 PHE 128 127 127 PHE PHE A . n 
B 1 129 ASN 129 128 128 ASN ASN A . n 
B 1 130 PRO 130 129 129 PRO PRO A . n 
B 1 131 PRO 131 130 130 PRO PRO A . n 
B 1 132 ALA 132 131 131 ALA ALA A . n 
B 1 133 LEU 133 132 132 LEU LEU A . n 
B 1 134 GLN 134 133 133 GLN GLN A . n 
B 1 135 ASP 135 134 134 ASP ASP A . n 
B 1 136 ALA 136 135 135 ALA ALA A . n 
B 1 137 TYR 137 136 136 TYR TYR A . n 
B 1 138 TYR 138 137 137 TYR TYR A . n 
B 1 139 ARG 139 138 138 ARG ARG A . n 
B 1 140 ALA 140 139 139 ALA ALA A . n 
B 1 141 ARG 141 140 140 ARG ARG A . n 
B 1 142 ALA 142 141 141 ALA ALA A . n 
B 1 143 GLY 143 142 142 GLY GLY A . n 
B 1 144 GLU 144 143 143 GLU GLU A . n 
B 1 145 ALA 145 144 144 ALA ALA A . n 
B 1 146 ALA 146 145 145 ALA ALA A . n 
B 1 147 ASN 147 146 146 ASN ASN A . n 
B 1 148 PHE 148 147 147 PHE PHE A . n 
B 1 149 CYS 149 148 148 CYS CYS A . n 
B 1 150 ALA 150 149 149 ALA ALA A . n 
B 1 151 LEU 151 150 150 LEU LEU A . n 
B 1 152 ILE 152 151 151 ILE ILE A . n 
B 1 153 LEU 153 152 152 LEU LEU A . n 
B 1 154 ALA 154 153 153 ALA ALA A . n 
B 1 155 TYR 155 154 154 TYR TYR A . n 
B 1 156 CYS 156 155 155 CYS CYS A . n 
B 1 157 ASN 157 156 156 ASN ASN A . n 
B 1 158 LYS 158 157 157 LYS LYS A . n 
B 1 159 THR 159 158 158 THR THR A . n 
B 1 160 VAL 160 159 159 VAL VAL A . n 
B 1 161 GLY 161 160 160 GLY GLY A . n 
B 1 162 GLU 162 161 161 GLU GLU A . n 
B 1 163 LEU 163 162 162 LEU LEU A . n 
B 1 164 GLY 164 163 163 GLY GLY A . n 
B 1 165 ASP 165 164 164 ASP ASP A . n 
B 1 166 VAL 166 165 165 VAL VAL A . n 
B 1 167 ARG 167 166 166 ARG ARG A . n 
B 1 168 GLU 168 167 167 GLU GLU A . n 
B 1 169 THR 169 168 168 THR THR A . n 
B 1 170 MET 170 169 169 MET MET A . n 
B 1 171 SER 171 170 170 SER SER A . n 
B 1 172 TYR 172 171 171 TYR TYR A . n 
B 1 173 LEU 173 172 172 LEU LEU A . n 
B 1 174 PHE 174 173 173 PHE PHE A . n 
B 1 175 GLN 175 174 174 GLN GLN A . n 
B 1 176 HIS 176 175 175 HIS HIS A . n 
B 1 177 ALA 177 176 176 ALA ALA A . n 
B 1 178 ASN 178 177 177 ASN ASN A . n 
B 1 179 LEU 179 178 178 LEU LEU A . n 
B 1 180 ASP 180 179 179 ASP ASP A . n 
B 1 181 SER 181 180 180 SER SER A . n 
B 1 182 CYS 182 181 181 CYS CYS A . n 
B 1 183 LYS 183 182 182 LYS LYS A . n 
B 1 184 ARG 184 183 183 ARG ARG A . n 
B 1 185 VAL 185 184 184 VAL VAL A . n 
B 1 186 LEU 186 185 185 LEU LEU A . n 
B 1 187 ASN 187 186 186 ASN ASN A . n 
B 1 188 VAL 188 187 187 VAL VAL A . n 
B 1 189 VAL 189 188 188 VAL VAL A . n 
B 1 190 CYS 190 189 189 CYS CYS A . n 
B 1 191 LYS 191 190 190 LYS LYS A . n 
B 1 192 THR 192 191 191 THR THR A . n 
B 1 193 CYS 193 192 192 CYS CYS A . n 
B 1 194 GLY 194 193 193 GLY GLY A . n 
B 1 195 GLN 195 194 194 GLN GLN A . n 
B 1 196 GLN 196 195 195 GLN GLN A . n 
B 1 197 GLN 197 196 196 GLN GLN A . n 
B 1 198 THR 198 197 197 THR THR A . n 
B 1 199 THR 199 198 198 THR THR A . n 
B 1 200 LEU 200 199 199 LEU LEU A . n 
B 1 201 LYS 201 200 200 LYS LYS A . n 
B 1 202 GLY 202 201 201 GLY GLY A . n 
B 1 203 VAL 203 202 202 VAL VAL A . n 
B 1 204 GLU 204 203 203 GLU GLU A . n 
B 1 205 ALA 205 204 204 ALA ALA A . n 
B 1 206 VAL 206 205 205 VAL VAL A . n 
B 1 207 MET 207 206 206 MET MET A . n 
B 1 208 TYR 208 207 207 TYR TYR A . n 
B 1 209 MET 209 208 208 MET MET A . n 
B 1 210 GLY 210 209 209 GLY GLY A . n 
B 1 211 THR 211 210 210 THR THR A . n 
B 1 212 LEU 212 211 211 LEU LEU A . n 
B 1 213 SER 213 212 212 SER SER A . n 
B 1 214 TYR 214 213 213 TYR TYR A . n 
B 1 215 GLU 215 214 214 GLU GLU A . n 
B 1 216 GLN 216 215 215 GLN GLN A . n 
B 1 217 PHE 217 216 216 PHE PHE A . n 
B 1 218 LYS 218 217 217 LYS LYS A . n 
B 1 219 LYS 219 218 218 LYS LYS A . n 
B 1 220 GLY 220 219 219 GLY GLY A . n 
B 1 221 VAL 221 220 220 VAL VAL A . n 
B 1 222 GLN 222 221 221 GLN GLN A . n 
B 1 223 ILE 223 222 222 ILE ILE A . n 
B 1 224 PRO 224 223 223 PRO PRO A . n 
B 1 225 CYS 225 224 224 CYS CYS A . n 
B 1 226 THR 226 225 225 THR THR A . n 
B 1 227 CYS 227 226 226 CYS CYS A . n 
B 1 228 GLY 228 227 227 GLY GLY A . n 
B 1 229 LYS 229 228 228 LYS LYS A . n 
B 1 230 GLN 230 229 229 GLN GLN A . n 
B 1 231 ALA 231 230 230 ALA ALA A . n 
B 1 232 THR 232 231 231 THR THR A . n 
B 1 233 LYS 233 232 232 LYS LYS A . n 
B 1 234 TYR 234 233 233 TYR TYR A . n 
B 1 235 LEU 235 234 234 LEU LEU A . n 
B 1 236 VAL 236 235 235 VAL VAL A . n 
B 1 237 GLN 237 236 236 GLN GLN A . n 
B 1 238 GLN 238 237 237 GLN GLN A . n 
B 1 239 GLU 239 238 238 GLU GLU A . n 
B 1 240 SER 240 239 239 SER SER A . n 
B 1 241 PRO 241 240 240 PRO PRO A . n 
B 1 242 PHE 242 241 241 PHE PHE A . n 
B 1 243 VAL 243 242 242 VAL VAL A . n 
B 1 244 MET 244 243 243 MET MET A . n 
B 1 245 MET 245 244 244 MET MET A . n 
B 1 246 SER 246 245 245 SER SER A . n 
B 1 247 ALA 247 246 246 ALA ALA A . n 
B 1 248 PRO 248 247 247 PRO PRO A . n 
B 1 249 PRO 249 248 248 PRO PRO A . n 
B 1 250 ALA 250 249 249 ALA ALA A . n 
B 1 251 GLN 251 250 250 GLN GLN A . n 
B 1 252 TYR 252 251 251 TYR TYR A . n 
B 1 253 GLU 253 252 252 GLU GLU A . n 
B 1 254 LEU 254 253 253 LEU LEU A . n 
B 1 255 LYS 255 254 254 LYS LYS A . n 
B 1 256 HIS 256 255 255 HIS HIS A . n 
B 1 257 GLY 257 256 256 GLY GLY A . n 
B 1 258 THR 258 257 257 THR THR A . n 
B 1 259 PHE 259 258 258 PHE PHE A . n 
B 1 260 THR 260 259 259 THR THR A . n 
B 1 261 CYS 261 260 260 CYS CYS A . n 
B 1 262 ALA 262 261 261 ALA ALA A . n 
B 1 263 SER 263 262 262 SER SER A . n 
B 1 264 GLU 264 263 263 GLU GLU A . n 
B 1 265 TYR 265 264 264 TYR TYR A . n 
B 1 266 THR 266 265 265 THR THR A . n 
B 1 267 GLY 267 266 266 GLY GLY A . n 
B 1 268 ASN 268 267 267 ASN ASN A . n 
B 1 269 TYR 269 268 268 TYR TYR A . n 
B 1 270 GLN 270 269 269 GLN GLN A . n 
B 1 271 CYS 271 270 270 CYS CYS A . n 
B 1 272 GLY 272 271 271 GLY GLY A . n 
B 1 273 HIS 273 272 272 HIS HIS A . n 
B 1 274 TYR 274 273 273 TYR TYR A . n 
B 1 275 LYS 275 274 274 LYS LYS A . n 
B 1 276 HIS 276 275 275 HIS HIS A . n 
B 1 277 ILE 277 276 276 ILE ILE A . n 
B 1 278 THR 278 277 277 THR THR A . n 
B 1 279 SER 279 278 278 SER SER A . n 
B 1 280 LYS 280 279 279 LYS LYS A . n 
B 1 281 GLU 281 280 280 GLU GLU A . n 
B 1 282 THR 282 281 281 THR THR A . n 
B 1 283 LEU 283 282 282 LEU LEU A . n 
B 1 284 TYR 284 283 283 TYR TYR A . n 
B 1 285 CYS 285 284 284 CYS CYS A . n 
B 1 286 ILE 286 285 285 ILE ILE A . n 
B 1 287 ASP 287 286 286 ASP ASP A . n 
B 1 288 GLY 288 287 287 GLY GLY A . n 
B 1 289 ALA 289 288 288 ALA ALA A . n 
B 1 290 LEU 290 289 289 LEU LEU A . n 
B 1 291 LEU 291 290 290 LEU LEU A . n 
B 1 292 THR 292 291 291 THR THR A . n 
B 1 293 LYS 293 292 292 LYS LYS A . n 
B 1 294 SER 294 293 293 SER SER A . n 
B 1 295 SER 295 294 294 SER SER A . n 
B 1 296 GLU 296 295 295 GLU GLU A . n 
B 1 297 TYR 297 296 296 TYR TYR A . n 
B 1 298 LYS 298 297 297 LYS LYS A . n 
B 1 299 GLY 299 298 298 GLY GLY A . n 
B 1 300 PRO 300 299 299 PRO PRO A . n 
B 1 301 ILE 301 300 300 ILE ILE A . n 
B 1 302 THR 302 301 301 THR THR A . n 
B 1 303 ASP 303 302 302 ASP ASP A . n 
B 1 304 VAL 304 303 303 VAL VAL A . n 
B 1 305 PHE 305 304 304 PHE PHE A . n 
B 1 306 TYR 306 305 305 TYR TYR A . n 
B 1 307 LYS 307 306 306 LYS LYS A . n 
B 1 308 GLU 308 307 307 GLU GLU A . n 
B 1 309 ASN 309 308 308 ASN ASN A . n 
B 1 310 SER 310 309 309 SER SER A . n 
B 1 311 TYR 311 310 310 TYR TYR A . n 
B 1 312 THR 312 311 311 THR THR A . n 
B 1 313 THR 313 312 312 THR THR A . n 
B 1 314 THR 314 313 313 THR THR A . n 
B 1 315 ILE 315 314 314 ILE ILE A . n 
B 1 316 LYS 316 315 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1LZ5 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1LZ5 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 ZN    1   401 361 ZN    ZN  B . 
D 2 ZN    1   402 362 ZN    ZN  B . 
E 3 A1LZ5 1   403 400 A1LZ5 273 B . 
F 3 A1LZ5 1   401 400 A1LZ5 273 A . 
G 2 ZN    1   402 361 ZN    ZN  A . 
H 2 ZN    1   403 362 ZN    ZN  A . 
I 4 HOH   1   501 27  HOH   HOH B . 
I 4 HOH   2   502 117 HOH   HOH B . 
I 4 HOH   3   503 97  HOH   HOH B . 
I 4 HOH   4   504 2   HOH   HOH B . 
I 4 HOH   5   505 175 HOH   HOH B . 
I 4 HOH   6   506 32  HOH   HOH B . 
I 4 HOH   7   507 182 HOH   HOH B . 
I 4 HOH   8   508 7   HOH   HOH B . 
I 4 HOH   9   509 30  HOH   HOH B . 
I 4 HOH   10  510 52  HOH   HOH B . 
I 4 HOH   11  511 171 HOH   HOH B . 
I 4 HOH   12  512 40  HOH   HOH B . 
I 4 HOH   13  513 116 HOH   HOH B . 
I 4 HOH   14  514 146 HOH   HOH B . 
I 4 HOH   15  515 129 HOH   HOH B . 
I 4 HOH   16  516 126 HOH   HOH B . 
I 4 HOH   17  517 72  HOH   HOH B . 
I 4 HOH   18  518 38  HOH   HOH B . 
I 4 HOH   19  519 26  HOH   HOH B . 
I 4 HOH   20  520 98  HOH   HOH B . 
I 4 HOH   21  521 139 HOH   HOH B . 
I 4 HOH   22  522 25  HOH   HOH B . 
I 4 HOH   23  523 35  HOH   HOH B . 
I 4 HOH   24  524 115 HOH   HOH B . 
I 4 HOH   25  525 8   HOH   HOH B . 
I 4 HOH   26  526 4   HOH   HOH B . 
I 4 HOH   27  527 29  HOH   HOH B . 
I 4 HOH   28  528 34  HOH   HOH B . 
I 4 HOH   29  529 107 HOH   HOH B . 
I 4 HOH   30  530 145 HOH   HOH B . 
I 4 HOH   31  531 157 HOH   HOH B . 
I 4 HOH   32  532 18  HOH   HOH B . 
I 4 HOH   33  533 124 HOH   HOH B . 
I 4 HOH   34  534 31  HOH   HOH B . 
I 4 HOH   35  535 50  HOH   HOH B . 
I 4 HOH   36  536 67  HOH   HOH B . 
I 4 HOH   37  537 91  HOH   HOH B . 
I 4 HOH   38  538 3   HOH   HOH B . 
I 4 HOH   39  539 16  HOH   HOH B . 
I 4 HOH   40  540 132 HOH   HOH B . 
I 4 HOH   41  541 66  HOH   HOH B . 
I 4 HOH   42  542 14  HOH   HOH B . 
I 4 HOH   43  543 61  HOH   HOH B . 
I 4 HOH   44  544 154 HOH   HOH B . 
I 4 HOH   45  545 99  HOH   HOH B . 
I 4 HOH   46  546 118 HOH   HOH B . 
I 4 HOH   47  547 180 HOH   HOH B . 
I 4 HOH   48  548 21  HOH   HOH B . 
I 4 HOH   49  549 105 HOH   HOH B . 
I 4 HOH   50  550 51  HOH   HOH B . 
I 4 HOH   51  551 81  HOH   HOH B . 
I 4 HOH   52  552 12  HOH   HOH B . 
I 4 HOH   53  553 164 HOH   HOH B . 
I 4 HOH   54  554 127 HOH   HOH B . 
I 4 HOH   55  555 68  HOH   HOH B . 
I 4 HOH   56  556 167 HOH   HOH B . 
I 4 HOH   57  557 125 HOH   HOH B . 
I 4 HOH   58  558 113 HOH   HOH B . 
I 4 HOH   59  559 158 HOH   HOH B . 
I 4 HOH   60  560 22  HOH   HOH B . 
I 4 HOH   61  561 9   HOH   HOH B . 
I 4 HOH   62  562 24  HOH   HOH B . 
I 4 HOH   63  563 133 HOH   HOH B . 
I 4 HOH   64  564 188 HOH   HOH B . 
I 4 HOH   65  565 111 HOH   HOH B . 
I 4 HOH   66  566 114 HOH   HOH B . 
I 4 HOH   67  567 85  HOH   HOH B . 
I 4 HOH   68  568 48  HOH   HOH B . 
I 4 HOH   69  569 108 HOH   HOH B . 
I 4 HOH   70  570 170 HOH   HOH B . 
I 4 HOH   71  571 179 HOH   HOH B . 
I 4 HOH   72  572 70  HOH   HOH B . 
I 4 HOH   73  573 17  HOH   HOH B . 
I 4 HOH   74  574 165 HOH   HOH B . 
I 4 HOH   75  575 138 HOH   HOH B . 
I 4 HOH   76  576 149 HOH   HOH B . 
I 4 HOH   77  577 177 HOH   HOH B . 
I 4 HOH   78  578 74  HOH   HOH B . 
I 4 HOH   79  579 176 HOH   HOH B . 
I 4 HOH   80  580 135 HOH   HOH B . 
I 4 HOH   81  581 155 HOH   HOH B . 
I 4 HOH   82  582 189 HOH   HOH B . 
I 4 HOH   83  583 151 HOH   HOH B . 
I 4 HOH   84  584 159 HOH   HOH B . 
J 4 HOH   1   501 69  HOH   HOH A . 
J 4 HOH   2   502 20  HOH   HOH A . 
J 4 HOH   3   503 150 HOH   HOH A . 
J 4 HOH   4   504 136 HOH   HOH A . 
J 4 HOH   5   505 77  HOH   HOH A . 
J 4 HOH   6   506 1   HOH   HOH A . 
J 4 HOH   7   507 10  HOH   HOH A . 
J 4 HOH   8   508 93  HOH   HOH A . 
J 4 HOH   9   509 19  HOH   HOH A . 
J 4 HOH   10  510 92  HOH   HOH A . 
J 4 HOH   11  511 41  HOH   HOH A . 
J 4 HOH   12  512 15  HOH   HOH A . 
J 4 HOH   13  513 101 HOH   HOH A . 
J 4 HOH   14  514 65  HOH   HOH A . 
J 4 HOH   15  515 73  HOH   HOH A . 
J 4 HOH   16  516 42  HOH   HOH A . 
J 4 HOH   17  517 47  HOH   HOH A . 
J 4 HOH   18  518 140 HOH   HOH A . 
J 4 HOH   19  519 62  HOH   HOH A . 
J 4 HOH   20  520 174 HOH   HOH A . 
J 4 HOH   21  521 187 HOH   HOH A . 
J 4 HOH   22  522 94  HOH   HOH A . 
J 4 HOH   23  523 130 HOH   HOH A . 
J 4 HOH   24  524 148 HOH   HOH A . 
J 4 HOH   25  525 123 HOH   HOH A . 
J 4 HOH   26  526 6   HOH   HOH A . 
J 4 HOH   27  527 128 HOH   HOH A . 
J 4 HOH   28  528 143 HOH   HOH A . 
J 4 HOH   29  529 28  HOH   HOH A . 
J 4 HOH   30  530 45  HOH   HOH A . 
J 4 HOH   31  531 110 HOH   HOH A . 
J 4 HOH   32  532 78  HOH   HOH A . 
J 4 HOH   33  533 137 HOH   HOH A . 
J 4 HOH   34  534 54  HOH   HOH A . 
J 4 HOH   35  535 56  HOH   HOH A . 
J 4 HOH   36  536 104 HOH   HOH A . 
J 4 HOH   37  537 55  HOH   HOH A . 
J 4 HOH   38  538 60  HOH   HOH A . 
J 4 HOH   39  539 131 HOH   HOH A . 
J 4 HOH   40  540 57  HOH   HOH A . 
J 4 HOH   41  541 89  HOH   HOH A . 
J 4 HOH   42  542 100 HOH   HOH A . 
J 4 HOH   43  543 44  HOH   HOH A . 
J 4 HOH   44  544 39  HOH   HOH A . 
J 4 HOH   45  545 33  HOH   HOH A . 
J 4 HOH   46  546 43  HOH   HOH A . 
J 4 HOH   47  547 82  HOH   HOH A . 
J 4 HOH   48  548 63  HOH   HOH A . 
J 4 HOH   49  549 79  HOH   HOH A . 
J 4 HOH   50  550 87  HOH   HOH A . 
J 4 HOH   51  551 46  HOH   HOH A . 
J 4 HOH   52  552 152 HOH   HOH A . 
J 4 HOH   53  553 76  HOH   HOH A . 
J 4 HOH   54  554 134 HOH   HOH A . 
J 4 HOH   55  555 71  HOH   HOH A . 
J 4 HOH   56  556 186 HOH   HOH A . 
J 4 HOH   57  557 121 HOH   HOH A . 
J 4 HOH   58  558 75  HOH   HOH A . 
J 4 HOH   59  559 11  HOH   HOH A . 
J 4 HOH   60  560 103 HOH   HOH A . 
J 4 HOH   61  561 5   HOH   HOH A . 
J 4 HOH   62  562 58  HOH   HOH A . 
J 4 HOH   63  563 142 HOH   HOH A . 
J 4 HOH   64  564 36  HOH   HOH A . 
J 4 HOH   65  565 53  HOH   HOH A . 
J 4 HOH   66  566 49  HOH   HOH A . 
J 4 HOH   67  567 112 HOH   HOH A . 
J 4 HOH   68  568 13  HOH   HOH A . 
J 4 HOH   69  569 147 HOH   HOH A . 
J 4 HOH   70  570 161 HOH   HOH A . 
J 4 HOH   71  571 122 HOH   HOH A . 
J 4 HOH   72  572 169 HOH   HOH A . 
J 4 HOH   73  573 90  HOH   HOH A . 
J 4 HOH   74  574 84  HOH   HOH A . 
J 4 HOH   75  575 120 HOH   HOH A . 
J 4 HOH   76  576 183 HOH   HOH A . 
J 4 HOH   77  577 106 HOH   HOH A . 
J 4 HOH   78  578 88  HOH   HOH A . 
J 4 HOH   79  579 96  HOH   HOH A . 
J 4 HOH   80  580 109 HOH   HOH A . 
J 4 HOH   81  581 144 HOH   HOH A . 
J 4 HOH   82  582 86  HOH   HOH A . 
J 4 HOH   83  583 23  HOH   HOH A . 
J 4 HOH   84  584 83  HOH   HOH A . 
J 4 HOH   85  585 172 HOH   HOH A . 
J 4 HOH   86  586 181 HOH   HOH A . 
J 4 HOH   87  587 80  HOH   HOH A . 
J 4 HOH   88  588 95  HOH   HOH A . 
J 4 HOH   89  589 168 HOH   HOH A . 
J 4 HOH   90  590 141 HOH   HOH A . 
J 4 HOH   91  591 102 HOH   HOH A . 
J 4 HOH   92  592 163 HOH   HOH A . 
J 4 HOH   93  593 162 HOH   HOH A . 
J 4 HOH   94  594 160 HOH   HOH A . 
J 4 HOH   95  595 64  HOH   HOH A . 
J 4 HOH   96  596 178 HOH   HOH A . 
J 4 HOH   97  597 185 HOH   HOH A . 
J 4 HOH   98  598 119 HOH   HOH A . 
J 4 HOH   99  599 37  HOH   HOH A . 
J 4 HOH   100 600 184 HOH   HOH A . 
J 4 HOH   101 601 156 HOH   HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B LYS 190 ? CG ? A LYS 191 CG 
2 1 Y 1 B LYS 190 ? CD ? A LYS 191 CD 
3 1 Y 1 B LYS 190 ? CE ? A LYS 191 CE 
4 1 Y 1 B LYS 190 ? NZ ? A LYS 191 NZ 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? '(1.20.1_4487: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .                    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? autoXDS ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8YX2 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     60.632 
_cell.length_a_esd                 ? 
_cell.length_b                     98.322 
_cell.length_b_esd                 ? 
_cell.length_c                     145.686 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8YX2 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8YX2 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.04 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          59.54 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M Lithium sulfate monohydrate, 0.1M HEPES pH7.5, 25% w/v PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-05-28 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97918 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL02U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97918 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL02U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          33.40 
_reflns.entry_id                                       8YX2 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.31 
_reflns.d_resolution_low                               72.84 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     35393 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           90.10 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          6.24 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.06713 
_reflns.pdbx_Rpim_I_all                                0.04747 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   0.999 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.04747 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.31 
_reflns_shell.d_res_low                                     2.393 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.37 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3790 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               2.0 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.351 
_reflns_shell.pdbx_Rpim_I_all                               0.2482 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.933 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.39 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.2482 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8YX2 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.31 
_refine.ls_d_res_low                             72.84 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     35393 
_refine.ls_number_reflns_R_free                  1801 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    90.16 
_refine.ls_percent_reflns_R_free                 5.09 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2060 
_refine.ls_R_factor_R_free                       0.2563 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2032 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      7CJM 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 35.00 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.29 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        4974 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         68 
_refine_hist.number_atoms_solvent             185 
_refine_hist.number_atoms_total               5227 
_refine_hist.d_res_high                       2.31 
_refine_hist.d_res_low                        72.84 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.014  ? ?   ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.408  ? ?   ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 18.495 ? 708 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.057  ? 772 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.010  ? 886 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.31 2.37  . . 164 2756 98.00 . . . . 0.2760 . . . . . . . . . . . 0.3576 
'X-RAY DIFFRACTION' 2.37 2.44  . . 124 2806 98.00 . . . . 0.2605 . . . . . . . . . . . 0.3023 
'X-RAY DIFFRACTION' 2.44 2.52  . . 153 2800 98.00 . . . . 0.2491 . . . . . . . . . . . 0.3395 
'X-RAY DIFFRACTION' 2.52 2.61  . . 127 2779 98.00 . . . . 0.2597 . . . . . . . . . . . 0.3520 
'X-RAY DIFFRACTION' 2.61 2.62  . . 5   128  47.00 . . . . 0.3063 . . . . . . . . . . . 0.2302 
'X-RAY DIFFRACTION' 2.72 2.83  . . 126 2419 98.00 . . . . 0.2642 . . . . . . . . . . . 0.3218 
'X-RAY DIFFRACTION' 2.83 2.98  . . 148 2810 99.00 . . . . 0.2368 . . . . . . . . . . . 0.3084 
'X-RAY DIFFRACTION' 2.98 3.17  . . 144 2813 99.00 . . . . 0.2241 . . . . . . . . . . . 0.2477 
'X-RAY DIFFRACTION' 3.17 3.41  . . 165 2792 98.00 . . . . 0.2084 . . . . . . . . . . . 0.2614 
'X-RAY DIFFRACTION' 3.41 3.76  . . 164 2817 98.00 . . . . 0.1916 . . . . . . . . . . . 0.2369 
'X-RAY DIFFRACTION' 3.76 4.30  . . 169 2846 99.00 . . . . 0.1623 . . . . . . . . . . . 0.2469 
'X-RAY DIFFRACTION' 4.30 5.42  . . 155 2856 98.00 . . . . 0.1603 . . . . . . . . . . . 0.1943 
'X-RAY DIFFRACTION' 5.42 72.84 . . 157 2970 97.00 . . . . 0.1897 . . . . . . . . . . . 0.2272 
# 
_struct.entry_id                     8YX2 
_struct.title                        'Crystal Structure of SARS CoV-2 Papain-like Protease PLpro-C111S in Complex with GZNL-P4' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8YX2 
_struct_keywords.text            'SARS CoV-2, PAPAIN-LIKE PROTEINASE, NSP3, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 2 ? 
H N N 2 ? 
I N N 4 ? 
J N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    R1AB_SARS2 
_struct_ref.pdbx_db_accession          P0DTD1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFL
GRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVG
ELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESP
FVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK
;
_struct_ref.pdbx_align_begin           1564 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8YX2 B 2 ? 316 ? P0DTD1 1564 ? 1878 ? 1 315 
2 1 8YX2 A 2 ? 316 ? P0DTD1 1564 ? 1878 ? 1 315 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8YX2 GLY B 1   ? UNP P0DTD1 ?   ?    'expression tag'      0   1 
1 8YX2 SER B 112 ? UNP P0DTD1 CYS 1674 'engineered mutation' 111 2 
2 8YX2 GLY A 1   ? UNP P0DTD1 ?   ?    'expression tag'      0   3 
2 8YX2 SER A 112 ? UNP P0DTD1 CYS 1674 'engineered mutation' 111 4 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,D,E,I 
2 1 B,F,G,H,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 TYR A 28  ? GLY A 33  ? TYR B 27  GLY B 32  1 ? 6  
HELX_P HELX_P2  AA2 HIS A 48  ? GLU A 52  ? HIS B 47  GLU B 51  5 ? 5  
HELX_P HELX_P3  AA3 ASP A 62  ? HIS A 74  ? ASP B 61  HIS B 73  1 ? 13 
HELX_P HELX_P4  AA4 SER A 79  ? LYS A 92  ? SER B 78  LYS B 91  1 ? 14 
HELX_P HELX_P5  AA5 ASN A 111 ? GLN A 122 ? ASN B 110 GLN B 121 1 ? 12 
HELX_P HELX_P6  AA6 PRO A 130 ? GLY A 143 ? PRO B 129 GLY B 142 1 ? 14 
HELX_P HELX_P7  AA7 ALA A 145 ? ASN A 157 ? ALA B 144 ASN B 156 1 ? 13 
HELX_P HELX_P8  AA8 ASP A 165 ? GLN A 175 ? ASP B 164 GLN B 174 1 ? 11 
HELX_P HELX_P9  AA9 VAL A 203 ? ALA A 205 ? VAL B 202 ALA B 204 5 ? 3  
HELX_P HELX_P10 AB1 SER A 213 ? GLY A 220 ? SER B 212 GLY B 219 1 ? 8  
HELX_P HELX_P11 AB2 THR B 27  ? GLY B 33  ? THR A 26  GLY A 32  1 ? 7  
HELX_P HELX_P12 AB3 HIS B 48  ? GLU B 52  ? HIS A 47  GLU A 51  5 ? 5  
HELX_P HELX_P13 AB4 ASP B 62  ? HIS B 74  ? ASP A 61  HIS A 73  1 ? 13 
HELX_P HELX_P14 AB5 SER B 79  ? LYS B 92  ? SER A 78  LYS A 91  1 ? 14 
HELX_P HELX_P15 AB6 ASN B 111 ? GLN B 122 ? ASN A 110 GLN A 121 1 ? 12 
HELX_P HELX_P16 AB7 PRO B 130 ? ALA B 142 ? PRO A 129 ALA A 141 1 ? 13 
HELX_P HELX_P17 AB8 ALA B 145 ? CYS B 156 ? ALA A 144 CYS A 155 1 ? 12 
HELX_P HELX_P18 AB9 ASP B 165 ? GLN B 175 ? ASP A 164 GLN A 174 1 ? 11 
HELX_P HELX_P19 AC1 VAL B 203 ? ALA B 205 ? VAL A 202 ALA A 204 5 ? 3  
HELX_P HELX_P20 AC2 SER B 213 ? GLY B 220 ? SER A 212 GLY A 219 1 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A CYS 190 SG ? ? ? 1_555 D ZN . ZN ? ? B CYS 189 B ZN 402 1_555 ? ? ? ? ? ? ? 2.829 ? ? 
metalc2 metalc ? ? A CYS 227 O  ? ? ? 1_555 D ZN . ZN ? ? B CYS 226 B ZN 402 1_555 ? ? ? ? ? ? ? 2.326 ? ? 
metalc3 metalc ? ? A CYS 227 SG ? ? ? 1_555 D ZN . ZN ? ? B CYS 226 B ZN 402 1_555 ? ? ? ? ? ? ? 2.470 ? ? 
metalc4 metalc ? ? B CYS 190 SG ? ? ? 1_555 G ZN . ZN ? ? A CYS 189 A ZN 402 1_555 ? ? ? ? ? ? ? 2.572 ? ? 
metalc5 metalc ? ? B CYS 193 SG ? ? ? 1_555 G ZN . ZN ? ? A CYS 192 A ZN 402 1_555 ? ? ? ? ? ? ? 2.251 ? ? 
metalc6 metalc ? ? B CYS 225 SG ? ? ? 1_555 G ZN . ZN ? ? A CYS 224 A ZN 402 1_555 ? ? ? ? ? ? ? 2.389 ? ? 
metalc7 metalc ? ? B CYS 227 SG ? ? ? 1_555 G ZN . ZN ? ? A CYS 226 A ZN 402 1_555 ? ? ? ? ? ? ? 2.713 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 SG ? A CYS 190 ? B CYS 189 ? 1_555 ZN ? D ZN . ? B ZN 402 ? 1_555 O  ? A CYS 227 ? B CYS 226 ? 1_555 132.2 ? 
2 SG ? A CYS 190 ? B CYS 189 ? 1_555 ZN ? D ZN . ? B ZN 402 ? 1_555 SG ? A CYS 227 ? B CYS 226 ? 1_555 124.4 ? 
3 O  ? A CYS 227 ? B CYS 226 ? 1_555 ZN ? D ZN . ? B ZN 402 ? 1_555 SG ? A CYS 227 ? B CYS 226 ? 1_555 102.3 ? 
4 SG ? B CYS 190 ? A CYS 189 ? 1_555 ZN ? G ZN . ? A ZN 402 ? 1_555 SG ? B CYS 193 ? A CYS 192 ? 1_555 87.7  ? 
5 SG ? B CYS 190 ? A CYS 189 ? 1_555 ZN ? G ZN . ? A ZN 402 ? 1_555 SG ? B CYS 225 ? A CYS 224 ? 1_555 148.5 ? 
6 SG ? B CYS 193 ? A CYS 192 ? 1_555 ZN ? G ZN . ? A ZN 402 ? 1_555 SG ? B CYS 225 ? A CYS 224 ? 1_555 92.5  ? 
7 SG ? B CYS 190 ? A CYS 189 ? 1_555 ZN ? G ZN . ? A ZN 402 ? 1_555 SG ? B CYS 227 ? A CYS 226 ? 1_555 82.2  ? 
8 SG ? B CYS 193 ? A CYS 192 ? 1_555 ZN ? G ZN . ? A ZN 402 ? 1_555 SG ? B CYS 227 ? A CYS 226 ? 1_555 75.0  ? 
9 SG ? B CYS 225 ? A CYS 224 ? 1_555 ZN ? G ZN . ? A ZN 402 ? 1_555 SG ? B CYS 227 ? A CYS 226 ? 1_555 128.2 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 7 ? 
AA6 ? 5 ? 
AA7 ? 2 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB1 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 HIS A 18  ? ASP A 23  ? HIS B 17  ASP B 22  
AA1 2 THR A 5   ? THR A 11  ? THR B 4   THR B 10  
AA1 3 THR A 55  ? VAL A 58  ? THR B 54  VAL B 57  
AA1 4 THR A 35  ? LEU A 37  ? THR B 34  LEU B 36  
AA1 5 ALA A 40  ? ASP A 41  ? ALA B 39  ASP B 40  
AA2 1 GLN A 98  ? VAL A 99  ? GLN B 97  VAL B 98  
AA2 2 LEU A 102 ? THR A 103 ? LEU B 101 THR B 102 
AA3 1 GLN A 196 ? LYS A 201 ? GLN B 195 LYS B 200 
AA3 2 LYS A 183 ? VAL A 189 ? LYS B 182 VAL B 188 
AA3 3 ALA A 231 ? GLU A 239 ? ALA B 230 GLU B 238 
AA3 4 VAL A 221 ? ILE A 223 ? VAL B 220 ILE B 222 
AA4 1 GLN A 196 ? LYS A 201 ? GLN B 195 LYS B 200 
AA4 2 LYS A 183 ? VAL A 189 ? LYS B 182 VAL B 188 
AA4 3 ALA A 231 ? GLU A 239 ? ALA B 230 GLU B 238 
AA4 4 SER A 310 ? THR A 312 ? SER B 309 THR B 311 
AA5 1 MET A 207 ? MET A 209 ? MET B 206 MET B 208 
AA5 2 PHE A 242 ? LEU A 254 ? PHE B 241 LEU B 253 
AA5 3 TYR A 297 ? LYS A 307 ? TYR B 296 LYS B 306 
AA5 4 CYS A 261 ? THR A 266 ? CYS B 260 THR B 265 
AA5 5 HIS A 273 ? SER A 279 ? HIS B 272 SER B 278 
AA5 6 LEU A 283 ? ASP A 287 ? LEU B 282 ASP B 286 
AA5 7 LEU A 290 ? SER A 294 ? LEU B 289 SER B 293 
AA6 1 HIS B 18  ? ASP B 23  ? HIS A 17  ASP A 22  
AA6 2 THR B 5   ? THR B 11  ? THR A 4   THR A 10  
AA6 3 THR B 55  ? VAL B 58  ? THR A 54  VAL A 57  
AA6 4 THR B 35  ? LEU B 37  ? THR A 34  LEU A 36  
AA6 5 ALA B 40  ? ASP B 41  ? ALA A 39  ASP A 40  
AA7 1 GLN B 98  ? VAL B 99  ? GLN A 97  VAL A 98  
AA7 2 LEU B 102 ? THR B 103 ? LEU A 101 THR A 102 
AA8 1 GLN B 196 ? LYS B 201 ? GLN A 195 LYS A 200 
AA8 2 LYS B 183 ? VAL B 189 ? LYS A 182 VAL A 188 
AA8 3 GLN B 230 ? GLU B 239 ? GLN A 229 GLU A 238 
AA8 4 VAL B 221 ? PRO B 224 ? VAL A 220 PRO A 223 
AA9 1 GLN B 196 ? LYS B 201 ? GLN A 195 LYS A 200 
AA9 2 LYS B 183 ? VAL B 189 ? LYS A 182 VAL A 188 
AA9 3 GLN B 230 ? GLU B 239 ? GLN A 229 GLU A 238 
AA9 4 SER B 310 ? THR B 312 ? SER A 309 THR A 311 
AB1 1 MET B 207 ? MET B 209 ? MET A 206 MET A 208 
AB1 2 PHE B 242 ? GLU B 253 ? PHE A 241 GLU A 252 
AB1 3 LYS B 298 ? LYS B 307 ? LYS A 297 LYS A 306 
AB1 4 CYS B 261 ? THR B 266 ? CYS A 260 THR A 265 
AB1 5 HIS B 273 ? SER B 279 ? HIS A 272 SER A 278 
AB1 6 LEU B 283 ? ASP B 287 ? LEU A 282 ASP A 286 
AB1 7 LEU B 290 ? SER B 294 ? LEU A 289 SER A 293 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLN A 20  ? O GLN B 19  N VAL A 8   ? N VAL B 7   
AA1 2 3 N THR A 11  ? N THR B 10  O VAL A 58  ? O VAL B 57  
AA1 3 4 O TYR A 57  ? O TYR B 56  N TYR A 36  ? N TYR B 35  
AA1 4 5 N LEU A 37  ? N LEU B 36  O ALA A 40  ? O ALA B 39  
AA2 1 2 N VAL A 99  ? N VAL B 98  O LEU A 102 ? O LEU B 101 
AA3 1 2 O THR A 198 ? O THR B 197 N LEU A 186 ? N LEU B 185 
AA3 2 3 N LYS A 183 ? N LYS B 182 O GLU A 239 ? O GLU B 238 
AA3 3 4 O ALA A 231 ? O ALA B 230 N ILE A 223 ? N ILE B 222 
AA4 1 2 O THR A 198 ? O THR B 197 N LEU A 186 ? N LEU B 185 
AA4 2 3 N LYS A 183 ? N LYS B 182 O GLU A 239 ? O GLU B 238 
AA4 3 4 N GLN A 238 ? N GLN B 237 O TYR A 311 ? O TYR B 310 
AA5 1 2 N TYR A 208 ? N TYR B 207 O SER A 246 ? O SER B 245 
AA5 2 3 N VAL A 243 ? N VAL B 242 O TYR A 306 ? O TYR B 305 
AA5 3 4 O PHE A 305 ? O PHE B 304 N CYS A 261 ? N CYS B 260 
AA5 4 5 N GLU A 264 ? N GLU B 263 O LYS A 275 ? O LYS B 274 
AA5 5 6 N HIS A 276 ? N HIS B 275 O ILE A 286 ? O ILE B 285 
AA5 6 7 N ASP A 287 ? N ASP B 286 O LEU A 290 ? O LEU B 289 
AA6 1 2 O GLN B 20  ? O GLN A 19  N VAL B 8   ? N VAL A 7   
AA6 2 3 N PHE B 9   ? N PHE A 8   O PHE B 56  ? O PHE A 55  
AA6 3 4 O TYR B 57  ? O TYR A 56  N TYR B 36  ? N TYR A 35  
AA6 4 5 N LEU B 37  ? N LEU A 36  O ALA B 40  ? O ALA A 39  
AA7 1 2 N VAL B 99  ? N VAL A 98  O LEU B 102 ? O LEU A 101 
AA8 1 2 O THR B 198 ? O THR A 197 N LEU B 186 ? N LEU A 185 
AA8 2 3 N VAL B 185 ? N VAL A 184 O GLN B 237 ? O GLN A 236 
AA8 3 4 O LYS B 233 ? O LYS A 232 N VAL B 221 ? N VAL A 220 
AA9 1 2 O THR B 198 ? O THR A 197 N LEU B 186 ? N LEU A 185 
AA9 2 3 N VAL B 185 ? N VAL A 184 O GLN B 237 ? O GLN A 236 
AA9 3 4 N GLN B 238 ? N GLN A 237 O TYR B 311 ? O TYR A 310 
AB1 1 2 N TYR B 208 ? N TYR A 207 O SER B 246 ? O SER A 245 
AB1 2 3 N MET B 245 ? N MET A 244 O VAL B 304 ? O VAL A 303 
AB1 3 4 O PHE B 305 ? O PHE A 304 N CYS B 261 ? N CYS A 260 
AB1 4 5 N ALA B 262 ? N ALA A 261 O ILE B 277 ? O ILE A 276 
AB1 5 6 N HIS B 276 ? N HIS A 275 O ILE B 286 ? O ILE A 285 
AB1 6 7 N ASP B 287 ? N ASP A 286 O LEU B 290 ? O LEU A 289 
# 
_pdbx_entry_details.entry_id                   8YX2 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 VAL B 2   ? ? -115.78 77.11   
2  1 ASN B 13  ? ? 53.50   18.31   
3  1 MET B 23  ? ? -69.79  1.20    
4  1 PRO B 59  ? ? -59.31  98.48   
5  1 SER B 103 ? ? -117.39 -169.16 
6  1 GLN B 229 ? ? 45.01   77.92   
7  1 TYR B 268 ? ? -33.87  122.51  
8  1 CYS B 270 ? ? -150.59 33.80   
9  1 LYS B 279 ? ? -118.16 -118.98 
10 1 ASN B 308 ? ? -136.76 -65.75  
11 1 VAL A 2   ? ? -118.99 77.47   
12 1 SER A 24  ? ? -105.44 50.06   
13 1 PRO A 59  ? ? -59.65  108.22  
14 1 SER A 103 ? ? -108.85 -167.06 
15 1 ALA A 107 ? ? -171.37 148.82  
16 1 CYS A 226 ? ? -55.29  173.81  
17 1 SER A 239 ? ? 179.30  152.90  
18 1 THR A 259 ? ? -93.05  -65.63  
19 1 TYR A 268 ? ? -36.08  120.29  
20 1 CYS A 270 ? ? -155.53 26.69   
21 1 LYS A 279 ? ? -118.37 -115.81 
22 1 ASN A 308 ? ? -142.17 -69.43  
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       601 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.15 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 B GLY 0   ? A GLY 1   
2 1 Y 1 B CYS 224 ? A CYS 225 
3 1 Y 1 B LYS 315 ? A LYS 316 
4 1 Y 1 A GLY 0   ? B GLY 1   
5 1 Y 1 A LYS 315 ? B LYS 316 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1LZ5 C02  C  N N 1   
A1LZ5 C03  C  Y N 2   
A1LZ5 C04  C  Y N 3   
A1LZ5 C05  C  Y N 4   
A1LZ5 C07  C  N N 5   
A1LZ5 C08  C  N N 6   
A1LZ5 C10  C  N N 7   
A1LZ5 C11  C  N N 8   
A1LZ5 C12  C  N N 9   
A1LZ5 C13  C  Y N 10  
A1LZ5 C14  C  Y N 11  
A1LZ5 C15  C  Y N 12  
A1LZ5 C16  C  N N 13  
A1LZ5 C18  C  N N 14  
A1LZ5 C19  C  N N 15  
A1LZ5 C20  C  N N 16  
A1LZ5 C21  C  Y N 17  
A1LZ5 C22  C  Y N 18  
A1LZ5 C23  C  Y N 19  
A1LZ5 C24  C  Y N 20  
A1LZ5 C25  C  Y N 21  
A1LZ5 C26  C  Y N 22  
A1LZ5 C27  C  N N 23  
A1LZ5 C28  C  N N 24  
A1LZ5 C29  C  Y N 25  
A1LZ5 C30  C  Y N 26  
A1LZ5 C31  C  Y N 27  
A1LZ5 C32  C  Y N 28  
A1LZ5 N06  N  N N 29  
A1LZ5 N09  N  N N 30  
A1LZ5 N17  N  N N 31  
A1LZ5 O01  O  N N 32  
A1LZ5 H1   H  N N 33  
A1LZ5 H2   H  N N 34  
A1LZ5 H3   H  N N 35  
A1LZ5 H4   H  N N 36  
A1LZ5 H5   H  N N 37  
A1LZ5 H6   H  N N 38  
A1LZ5 H7   H  N N 39  
A1LZ5 H8   H  N N 40  
A1LZ5 H9   H  N N 41  
A1LZ5 H10  H  N N 42  
A1LZ5 H11  H  N N 43  
A1LZ5 H12  H  N N 44  
A1LZ5 H13  H  N N 45  
A1LZ5 H14  H  N N 46  
A1LZ5 H15  H  N N 47  
A1LZ5 H16  H  N N 48  
A1LZ5 H17  H  N N 49  
A1LZ5 H18  H  N N 50  
A1LZ5 H19  H  N N 51  
A1LZ5 H20  H  N N 52  
A1LZ5 H21  H  N N 53  
A1LZ5 H22  H  N N 54  
A1LZ5 H23  H  N N 55  
A1LZ5 H24  H  N N 56  
A1LZ5 H25  H  N N 57  
A1LZ5 H26  H  N N 58  
A1LZ5 H27  H  N N 59  
A1LZ5 H28  H  N N 60  
A1LZ5 H30  H  N N 61  
A1LZ5 H31  H  N N 62  
A1LZ5 H32  H  N N 63  
ALA   N    N  N N 64  
ALA   CA   C  N S 65  
ALA   C    C  N N 66  
ALA   O    O  N N 67  
ALA   CB   C  N N 68  
ALA   OXT  O  N N 69  
ALA   H    H  N N 70  
ALA   H2   H  N N 71  
ALA   HA   H  N N 72  
ALA   HB1  H  N N 73  
ALA   HB2  H  N N 74  
ALA   HB3  H  N N 75  
ALA   HXT  H  N N 76  
ARG   N    N  N N 77  
ARG   CA   C  N S 78  
ARG   C    C  N N 79  
ARG   O    O  N N 80  
ARG   CB   C  N N 81  
ARG   CG   C  N N 82  
ARG   CD   C  N N 83  
ARG   NE   N  N N 84  
ARG   CZ   C  N N 85  
ARG   NH1  N  N N 86  
ARG   NH2  N  N N 87  
ARG   OXT  O  N N 88  
ARG   H    H  N N 89  
ARG   H2   H  N N 90  
ARG   HA   H  N N 91  
ARG   HB2  H  N N 92  
ARG   HB3  H  N N 93  
ARG   HG2  H  N N 94  
ARG   HG3  H  N N 95  
ARG   HD2  H  N N 96  
ARG   HD3  H  N N 97  
ARG   HE   H  N N 98  
ARG   HH11 H  N N 99  
ARG   HH12 H  N N 100 
ARG   HH21 H  N N 101 
ARG   HH22 H  N N 102 
ARG   HXT  H  N N 103 
ASN   N    N  N N 104 
ASN   CA   C  N S 105 
ASN   C    C  N N 106 
ASN   O    O  N N 107 
ASN   CB   C  N N 108 
ASN   CG   C  N N 109 
ASN   OD1  O  N N 110 
ASN   ND2  N  N N 111 
ASN   OXT  O  N N 112 
ASN   H    H  N N 113 
ASN   H2   H  N N 114 
ASN   HA   H  N N 115 
ASN   HB2  H  N N 116 
ASN   HB3  H  N N 117 
ASN   HD21 H  N N 118 
ASN   HD22 H  N N 119 
ASN   HXT  H  N N 120 
ASP   N    N  N N 121 
ASP   CA   C  N S 122 
ASP   C    C  N N 123 
ASP   O    O  N N 124 
ASP   CB   C  N N 125 
ASP   CG   C  N N 126 
ASP   OD1  O  N N 127 
ASP   OD2  O  N N 128 
ASP   OXT  O  N N 129 
ASP   H    H  N N 130 
ASP   H2   H  N N 131 
ASP   HA   H  N N 132 
ASP   HB2  H  N N 133 
ASP   HB3  H  N N 134 
ASP   HD2  H  N N 135 
ASP   HXT  H  N N 136 
CYS   N    N  N N 137 
CYS   CA   C  N R 138 
CYS   C    C  N N 139 
CYS   O    O  N N 140 
CYS   CB   C  N N 141 
CYS   SG   S  N N 142 
CYS   OXT  O  N N 143 
CYS   H    H  N N 144 
CYS   H2   H  N N 145 
CYS   HA   H  N N 146 
CYS   HB2  H  N N 147 
CYS   HB3  H  N N 148 
CYS   HG   H  N N 149 
CYS   HXT  H  N N 150 
GLN   N    N  N N 151 
GLN   CA   C  N S 152 
GLN   C    C  N N 153 
GLN   O    O  N N 154 
GLN   CB   C  N N 155 
GLN   CG   C  N N 156 
GLN   CD   C  N N 157 
GLN   OE1  O  N N 158 
GLN   NE2  N  N N 159 
GLN   OXT  O  N N 160 
GLN   H    H  N N 161 
GLN   H2   H  N N 162 
GLN   HA   H  N N 163 
GLN   HB2  H  N N 164 
GLN   HB3  H  N N 165 
GLN   HG2  H  N N 166 
GLN   HG3  H  N N 167 
GLN   HE21 H  N N 168 
GLN   HE22 H  N N 169 
GLN   HXT  H  N N 170 
GLU   N    N  N N 171 
GLU   CA   C  N S 172 
GLU   C    C  N N 173 
GLU   O    O  N N 174 
GLU   CB   C  N N 175 
GLU   CG   C  N N 176 
GLU   CD   C  N N 177 
GLU   OE1  O  N N 178 
GLU   OE2  O  N N 179 
GLU   OXT  O  N N 180 
GLU   H    H  N N 181 
GLU   H2   H  N N 182 
GLU   HA   H  N N 183 
GLU   HB2  H  N N 184 
GLU   HB3  H  N N 185 
GLU   HG2  H  N N 186 
GLU   HG3  H  N N 187 
GLU   HE2  H  N N 188 
GLU   HXT  H  N N 189 
GLY   N    N  N N 190 
GLY   CA   C  N N 191 
GLY   C    C  N N 192 
GLY   O    O  N N 193 
GLY   OXT  O  N N 194 
GLY   H    H  N N 195 
GLY   H2   H  N N 196 
GLY   HA2  H  N N 197 
GLY   HA3  H  N N 198 
GLY   HXT  H  N N 199 
HIS   N    N  N N 200 
HIS   CA   C  N S 201 
HIS   C    C  N N 202 
HIS   O    O  N N 203 
HIS   CB   C  N N 204 
HIS   CG   C  Y N 205 
HIS   ND1  N  Y N 206 
HIS   CD2  C  Y N 207 
HIS   CE1  C  Y N 208 
HIS   NE2  N  Y N 209 
HIS   OXT  O  N N 210 
HIS   H    H  N N 211 
HIS   H2   H  N N 212 
HIS   HA   H  N N 213 
HIS   HB2  H  N N 214 
HIS   HB3  H  N N 215 
HIS   HD1  H  N N 216 
HIS   HD2  H  N N 217 
HIS   HE1  H  N N 218 
HIS   HE2  H  N N 219 
HIS   HXT  H  N N 220 
HOH   O    O  N N 221 
HOH   H1   H  N N 222 
HOH   H2   H  N N 223 
ILE   N    N  N N 224 
ILE   CA   C  N S 225 
ILE   C    C  N N 226 
ILE   O    O  N N 227 
ILE   CB   C  N S 228 
ILE   CG1  C  N N 229 
ILE   CG2  C  N N 230 
ILE   CD1  C  N N 231 
ILE   OXT  O  N N 232 
ILE   H    H  N N 233 
ILE   H2   H  N N 234 
ILE   HA   H  N N 235 
ILE   HB   H  N N 236 
ILE   HG12 H  N N 237 
ILE   HG13 H  N N 238 
ILE   HG21 H  N N 239 
ILE   HG22 H  N N 240 
ILE   HG23 H  N N 241 
ILE   HD11 H  N N 242 
ILE   HD12 H  N N 243 
ILE   HD13 H  N N 244 
ILE   HXT  H  N N 245 
LEU   N    N  N N 246 
LEU   CA   C  N S 247 
LEU   C    C  N N 248 
LEU   O    O  N N 249 
LEU   CB   C  N N 250 
LEU   CG   C  N N 251 
LEU   CD1  C  N N 252 
LEU   CD2  C  N N 253 
LEU   OXT  O  N N 254 
LEU   H    H  N N 255 
LEU   H2   H  N N 256 
LEU   HA   H  N N 257 
LEU   HB2  H  N N 258 
LEU   HB3  H  N N 259 
LEU   HG   H  N N 260 
LEU   HD11 H  N N 261 
LEU   HD12 H  N N 262 
LEU   HD13 H  N N 263 
LEU   HD21 H  N N 264 
LEU   HD22 H  N N 265 
LEU   HD23 H  N N 266 
LEU   HXT  H  N N 267 
LYS   N    N  N N 268 
LYS   CA   C  N S 269 
LYS   C    C  N N 270 
LYS   O    O  N N 271 
LYS   CB   C  N N 272 
LYS   CG   C  N N 273 
LYS   CD   C  N N 274 
LYS   CE   C  N N 275 
LYS   NZ   N  N N 276 
LYS   OXT  O  N N 277 
LYS   H    H  N N 278 
LYS   H2   H  N N 279 
LYS   HA   H  N N 280 
LYS   HB2  H  N N 281 
LYS   HB3  H  N N 282 
LYS   HG2  H  N N 283 
LYS   HG3  H  N N 284 
LYS   HD2  H  N N 285 
LYS   HD3  H  N N 286 
LYS   HE2  H  N N 287 
LYS   HE3  H  N N 288 
LYS   HZ1  H  N N 289 
LYS   HZ2  H  N N 290 
LYS   HZ3  H  N N 291 
LYS   HXT  H  N N 292 
MET   N    N  N N 293 
MET   CA   C  N S 294 
MET   C    C  N N 295 
MET   O    O  N N 296 
MET   CB   C  N N 297 
MET   CG   C  N N 298 
MET   SD   S  N N 299 
MET   CE   C  N N 300 
MET   OXT  O  N N 301 
MET   H    H  N N 302 
MET   H2   H  N N 303 
MET   HA   H  N N 304 
MET   HB2  H  N N 305 
MET   HB3  H  N N 306 
MET   HG2  H  N N 307 
MET   HG3  H  N N 308 
MET   HE1  H  N N 309 
MET   HE2  H  N N 310 
MET   HE3  H  N N 311 
MET   HXT  H  N N 312 
PHE   N    N  N N 313 
PHE   CA   C  N S 314 
PHE   C    C  N N 315 
PHE   O    O  N N 316 
PHE   CB   C  N N 317 
PHE   CG   C  Y N 318 
PHE   CD1  C  Y N 319 
PHE   CD2  C  Y N 320 
PHE   CE1  C  Y N 321 
PHE   CE2  C  Y N 322 
PHE   CZ   C  Y N 323 
PHE   OXT  O  N N 324 
PHE   H    H  N N 325 
PHE   H2   H  N N 326 
PHE   HA   H  N N 327 
PHE   HB2  H  N N 328 
PHE   HB3  H  N N 329 
PHE   HD1  H  N N 330 
PHE   HD2  H  N N 331 
PHE   HE1  H  N N 332 
PHE   HE2  H  N N 333 
PHE   HZ   H  N N 334 
PHE   HXT  H  N N 335 
PRO   N    N  N N 336 
PRO   CA   C  N S 337 
PRO   C    C  N N 338 
PRO   O    O  N N 339 
PRO   CB   C  N N 340 
PRO   CG   C  N N 341 
PRO   CD   C  N N 342 
PRO   OXT  O  N N 343 
PRO   H    H  N N 344 
PRO   HA   H  N N 345 
PRO   HB2  H  N N 346 
PRO   HB3  H  N N 347 
PRO   HG2  H  N N 348 
PRO   HG3  H  N N 349 
PRO   HD2  H  N N 350 
PRO   HD3  H  N N 351 
PRO   HXT  H  N N 352 
SER   N    N  N N 353 
SER   CA   C  N S 354 
SER   C    C  N N 355 
SER   O    O  N N 356 
SER   CB   C  N N 357 
SER   OG   O  N N 358 
SER   OXT  O  N N 359 
SER   H    H  N N 360 
SER   H2   H  N N 361 
SER   HA   H  N N 362 
SER   HB2  H  N N 363 
SER   HB3  H  N N 364 
SER   HG   H  N N 365 
SER   HXT  H  N N 366 
THR   N    N  N N 367 
THR   CA   C  N S 368 
THR   C    C  N N 369 
THR   O    O  N N 370 
THR   CB   C  N R 371 
THR   OG1  O  N N 372 
THR   CG2  C  N N 373 
THR   OXT  O  N N 374 
THR   H    H  N N 375 
THR   H2   H  N N 376 
THR   HA   H  N N 377 
THR   HB   H  N N 378 
THR   HG1  H  N N 379 
THR   HG21 H  N N 380 
THR   HG22 H  N N 381 
THR   HG23 H  N N 382 
THR   HXT  H  N N 383 
TRP   N    N  N N 384 
TRP   CA   C  N S 385 
TRP   C    C  N N 386 
TRP   O    O  N N 387 
TRP   CB   C  N N 388 
TRP   CG   C  Y N 389 
TRP   CD1  C  Y N 390 
TRP   CD2  C  Y N 391 
TRP   NE1  N  Y N 392 
TRP   CE2  C  Y N 393 
TRP   CE3  C  Y N 394 
TRP   CZ2  C  Y N 395 
TRP   CZ3  C  Y N 396 
TRP   CH2  C  Y N 397 
TRP   OXT  O  N N 398 
TRP   H    H  N N 399 
TRP   H2   H  N N 400 
TRP   HA   H  N N 401 
TRP   HB2  H  N N 402 
TRP   HB3  H  N N 403 
TRP   HD1  H  N N 404 
TRP   HE1  H  N N 405 
TRP   HE3  H  N N 406 
TRP   HZ2  H  N N 407 
TRP   HZ3  H  N N 408 
TRP   HH2  H  N N 409 
TRP   HXT  H  N N 410 
TYR   N    N  N N 411 
TYR   CA   C  N S 412 
TYR   C    C  N N 413 
TYR   O    O  N N 414 
TYR   CB   C  N N 415 
TYR   CG   C  Y N 416 
TYR   CD1  C  Y N 417 
TYR   CD2  C  Y N 418 
TYR   CE1  C  Y N 419 
TYR   CE2  C  Y N 420 
TYR   CZ   C  Y N 421 
TYR   OH   O  N N 422 
TYR   OXT  O  N N 423 
TYR   H    H  N N 424 
TYR   H2   H  N N 425 
TYR   HA   H  N N 426 
TYR   HB2  H  N N 427 
TYR   HB3  H  N N 428 
TYR   HD1  H  N N 429 
TYR   HD2  H  N N 430 
TYR   HE1  H  N N 431 
TYR   HE2  H  N N 432 
TYR   HH   H  N N 433 
TYR   HXT  H  N N 434 
VAL   N    N  N N 435 
VAL   CA   C  N S 436 
VAL   C    C  N N 437 
VAL   O    O  N N 438 
VAL   CB   C  N N 439 
VAL   CG1  C  N N 440 
VAL   CG2  C  N N 441 
VAL   OXT  O  N N 442 
VAL   H    H  N N 443 
VAL   H2   H  N N 444 
VAL   HA   H  N N 445 
VAL   HB   H  N N 446 
VAL   HG11 H  N N 447 
VAL   HG12 H  N N 448 
VAL   HG13 H  N N 449 
VAL   HG21 H  N N 450 
VAL   HG22 H  N N 451 
VAL   HG23 H  N N 452 
VAL   HXT  H  N N 453 
ZN    ZN   ZN N N 454 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1LZ5 C27 C28  sing N N 1   
A1LZ5 C27 C26  sing N N 2   
A1LZ5 C28 C30  sing N N 3   
A1LZ5 C26 C25  doub Y N 4   
A1LZ5 C26 C29  sing Y N 5   
A1LZ5 C30 C29  doub Y N 6   
A1LZ5 C30 C31  sing Y N 7   
A1LZ5 C25 C24  sing Y N 8   
A1LZ5 C29 C22  sing Y N 9   
A1LZ5 C31 C32  doub Y N 10  
A1LZ5 C24 C23  doub Y N 11  
A1LZ5 C22 C23  sing Y N 12  
A1LZ5 C22 C21  doub Y N 13  
A1LZ5 C32 C21  sing Y N 14  
A1LZ5 C21 C18  sing N N 15  
A1LZ5 C20 C19  sing N N 16  
A1LZ5 C20 C18  sing N N 17  
A1LZ5 C19 C18  sing N N 18  
A1LZ5 C18 N17  sing N N 19  
A1LZ5 O01 C02  doub N N 20  
A1LZ5 N17 C02  sing N N 21  
A1LZ5 C02 C03  sing N N 22  
A1LZ5 C03 C04  doub Y N 23  
A1LZ5 C03 C15  sing Y N 24  
A1LZ5 C16 C15  sing N N 25  
A1LZ5 C04 C05  sing Y N 26  
A1LZ5 C15 C14  doub Y N 27  
A1LZ5 C12 C11  sing N N 28  
A1LZ5 C12 N06  sing N N 29  
A1LZ5 C11 N09  sing N N 30  
A1LZ5 C05 N06  sing N N 31  
A1LZ5 C05 C13  doub Y N 32  
A1LZ5 N06 C07  sing N N 33  
A1LZ5 C14 C13  sing Y N 34  
A1LZ5 N09 C10  sing N N 35  
A1LZ5 N09 C08  sing N N 36  
A1LZ5 C07 C08  sing N N 37  
A1LZ5 C04 H1   sing N N 38  
A1LZ5 C07 H2   sing N N 39  
A1LZ5 C07 H3   sing N N 40  
A1LZ5 C08 H4   sing N N 41  
A1LZ5 C08 H5   sing N N 42  
A1LZ5 C10 H6   sing N N 43  
A1LZ5 C10 H7   sing N N 44  
A1LZ5 C10 H8   sing N N 45  
A1LZ5 C11 H9   sing N N 46  
A1LZ5 C11 H10  sing N N 47  
A1LZ5 C12 H11  sing N N 48  
A1LZ5 C12 H12  sing N N 49  
A1LZ5 C13 H13  sing N N 50  
A1LZ5 C14 H14  sing N N 51  
A1LZ5 C16 H15  sing N N 52  
A1LZ5 C16 H16  sing N N 53  
A1LZ5 C16 H17  sing N N 54  
A1LZ5 C19 H18  sing N N 55  
A1LZ5 C19 H19  sing N N 56  
A1LZ5 C20 H20  sing N N 57  
A1LZ5 C20 H21  sing N N 58  
A1LZ5 C23 H22  sing N N 59  
A1LZ5 C24 H23  sing N N 60  
A1LZ5 C25 H24  sing N N 61  
A1LZ5 C27 H25  sing N N 62  
A1LZ5 C28 H26  sing N N 63  
A1LZ5 C31 H27  sing N N 64  
A1LZ5 C32 H28  sing N N 65  
A1LZ5 N17 H30  sing N N 66  
A1LZ5 C27 H31  sing N N 67  
A1LZ5 C28 H32  sing N N 68  
ALA   N   CA   sing N N 69  
ALA   N   H    sing N N 70  
ALA   N   H2   sing N N 71  
ALA   CA  C    sing N N 72  
ALA   CA  CB   sing N N 73  
ALA   CA  HA   sing N N 74  
ALA   C   O    doub N N 75  
ALA   C   OXT  sing N N 76  
ALA   CB  HB1  sing N N 77  
ALA   CB  HB2  sing N N 78  
ALA   CB  HB3  sing N N 79  
ALA   OXT HXT  sing N N 80  
ARG   N   CA   sing N N 81  
ARG   N   H    sing N N 82  
ARG   N   H2   sing N N 83  
ARG   CA  C    sing N N 84  
ARG   CA  CB   sing N N 85  
ARG   CA  HA   sing N N 86  
ARG   C   O    doub N N 87  
ARG   C   OXT  sing N N 88  
ARG   CB  CG   sing N N 89  
ARG   CB  HB2  sing N N 90  
ARG   CB  HB3  sing N N 91  
ARG   CG  CD   sing N N 92  
ARG   CG  HG2  sing N N 93  
ARG   CG  HG3  sing N N 94  
ARG   CD  NE   sing N N 95  
ARG   CD  HD2  sing N N 96  
ARG   CD  HD3  sing N N 97  
ARG   NE  CZ   sing N N 98  
ARG   NE  HE   sing N N 99  
ARG   CZ  NH1  sing N N 100 
ARG   CZ  NH2  doub N N 101 
ARG   NH1 HH11 sing N N 102 
ARG   NH1 HH12 sing N N 103 
ARG   NH2 HH21 sing N N 104 
ARG   NH2 HH22 sing N N 105 
ARG   OXT HXT  sing N N 106 
ASN   N   CA   sing N N 107 
ASN   N   H    sing N N 108 
ASN   N   H2   sing N N 109 
ASN   CA  C    sing N N 110 
ASN   CA  CB   sing N N 111 
ASN   CA  HA   sing N N 112 
ASN   C   O    doub N N 113 
ASN   C   OXT  sing N N 114 
ASN   CB  CG   sing N N 115 
ASN   CB  HB2  sing N N 116 
ASN   CB  HB3  sing N N 117 
ASN   CG  OD1  doub N N 118 
ASN   CG  ND2  sing N N 119 
ASN   ND2 HD21 sing N N 120 
ASN   ND2 HD22 sing N N 121 
ASN   OXT HXT  sing N N 122 
ASP   N   CA   sing N N 123 
ASP   N   H    sing N N 124 
ASP   N   H2   sing N N 125 
ASP   CA  C    sing N N 126 
ASP   CA  CB   sing N N 127 
ASP   CA  HA   sing N N 128 
ASP   C   O    doub N N 129 
ASP   C   OXT  sing N N 130 
ASP   CB  CG   sing N N 131 
ASP   CB  HB2  sing N N 132 
ASP   CB  HB3  sing N N 133 
ASP   CG  OD1  doub N N 134 
ASP   CG  OD2  sing N N 135 
ASP   OD2 HD2  sing N N 136 
ASP   OXT HXT  sing N N 137 
CYS   N   CA   sing N N 138 
CYS   N   H    sing N N 139 
CYS   N   H2   sing N N 140 
CYS   CA  C    sing N N 141 
CYS   CA  CB   sing N N 142 
CYS   CA  HA   sing N N 143 
CYS   C   O    doub N N 144 
CYS   C   OXT  sing N N 145 
CYS   CB  SG   sing N N 146 
CYS   CB  HB2  sing N N 147 
CYS   CB  HB3  sing N N 148 
CYS   SG  HG   sing N N 149 
CYS   OXT HXT  sing N N 150 
GLN   N   CA   sing N N 151 
GLN   N   H    sing N N 152 
GLN   N   H2   sing N N 153 
GLN   CA  C    sing N N 154 
GLN   CA  CB   sing N N 155 
GLN   CA  HA   sing N N 156 
GLN   C   O    doub N N 157 
GLN   C   OXT  sing N N 158 
GLN   CB  CG   sing N N 159 
GLN   CB  HB2  sing N N 160 
GLN   CB  HB3  sing N N 161 
GLN   CG  CD   sing N N 162 
GLN   CG  HG2  sing N N 163 
GLN   CG  HG3  sing N N 164 
GLN   CD  OE1  doub N N 165 
GLN   CD  NE2  sing N N 166 
GLN   NE2 HE21 sing N N 167 
GLN   NE2 HE22 sing N N 168 
GLN   OXT HXT  sing N N 169 
GLU   N   CA   sing N N 170 
GLU   N   H    sing N N 171 
GLU   N   H2   sing N N 172 
GLU   CA  C    sing N N 173 
GLU   CA  CB   sing N N 174 
GLU   CA  HA   sing N N 175 
GLU   C   O    doub N N 176 
GLU   C   OXT  sing N N 177 
GLU   CB  CG   sing N N 178 
GLU   CB  HB2  sing N N 179 
GLU   CB  HB3  sing N N 180 
GLU   CG  CD   sing N N 181 
GLU   CG  HG2  sing N N 182 
GLU   CG  HG3  sing N N 183 
GLU   CD  OE1  doub N N 184 
GLU   CD  OE2  sing N N 185 
GLU   OE2 HE2  sing N N 186 
GLU   OXT HXT  sing N N 187 
GLY   N   CA   sing N N 188 
GLY   N   H    sing N N 189 
GLY   N   H2   sing N N 190 
GLY   CA  C    sing N N 191 
GLY   CA  HA2  sing N N 192 
GLY   CA  HA3  sing N N 193 
GLY   C   O    doub N N 194 
GLY   C   OXT  sing N N 195 
GLY   OXT HXT  sing N N 196 
HIS   N   CA   sing N N 197 
HIS   N   H    sing N N 198 
HIS   N   H2   sing N N 199 
HIS   CA  C    sing N N 200 
HIS   CA  CB   sing N N 201 
HIS   CA  HA   sing N N 202 
HIS   C   O    doub N N 203 
HIS   C   OXT  sing N N 204 
HIS   CB  CG   sing N N 205 
HIS   CB  HB2  sing N N 206 
HIS   CB  HB3  sing N N 207 
HIS   CG  ND1  sing Y N 208 
HIS   CG  CD2  doub Y N 209 
HIS   ND1 CE1  doub Y N 210 
HIS   ND1 HD1  sing N N 211 
HIS   CD2 NE2  sing Y N 212 
HIS   CD2 HD2  sing N N 213 
HIS   CE1 NE2  sing Y N 214 
HIS   CE1 HE1  sing N N 215 
HIS   NE2 HE2  sing N N 216 
HIS   OXT HXT  sing N N 217 
HOH   O   H1   sing N N 218 
HOH   O   H2   sing N N 219 
ILE   N   CA   sing N N 220 
ILE   N   H    sing N N 221 
ILE   N   H2   sing N N 222 
ILE   CA  C    sing N N 223 
ILE   CA  CB   sing N N 224 
ILE   CA  HA   sing N N 225 
ILE   C   O    doub N N 226 
ILE   C   OXT  sing N N 227 
ILE   CB  CG1  sing N N 228 
ILE   CB  CG2  sing N N 229 
ILE   CB  HB   sing N N 230 
ILE   CG1 CD1  sing N N 231 
ILE   CG1 HG12 sing N N 232 
ILE   CG1 HG13 sing N N 233 
ILE   CG2 HG21 sing N N 234 
ILE   CG2 HG22 sing N N 235 
ILE   CG2 HG23 sing N N 236 
ILE   CD1 HD11 sing N N 237 
ILE   CD1 HD12 sing N N 238 
ILE   CD1 HD13 sing N N 239 
ILE   OXT HXT  sing N N 240 
LEU   N   CA   sing N N 241 
LEU   N   H    sing N N 242 
LEU   N   H2   sing N N 243 
LEU   CA  C    sing N N 244 
LEU   CA  CB   sing N N 245 
LEU   CA  HA   sing N N 246 
LEU   C   O    doub N N 247 
LEU   C   OXT  sing N N 248 
LEU   CB  CG   sing N N 249 
LEU   CB  HB2  sing N N 250 
LEU   CB  HB3  sing N N 251 
LEU   CG  CD1  sing N N 252 
LEU   CG  CD2  sing N N 253 
LEU   CG  HG   sing N N 254 
LEU   CD1 HD11 sing N N 255 
LEU   CD1 HD12 sing N N 256 
LEU   CD1 HD13 sing N N 257 
LEU   CD2 HD21 sing N N 258 
LEU   CD2 HD22 sing N N 259 
LEU   CD2 HD23 sing N N 260 
LEU   OXT HXT  sing N N 261 
LYS   N   CA   sing N N 262 
LYS   N   H    sing N N 263 
LYS   N   H2   sing N N 264 
LYS   CA  C    sing N N 265 
LYS   CA  CB   sing N N 266 
LYS   CA  HA   sing N N 267 
LYS   C   O    doub N N 268 
LYS   C   OXT  sing N N 269 
LYS   CB  CG   sing N N 270 
LYS   CB  HB2  sing N N 271 
LYS   CB  HB3  sing N N 272 
LYS   CG  CD   sing N N 273 
LYS   CG  HG2  sing N N 274 
LYS   CG  HG3  sing N N 275 
LYS   CD  CE   sing N N 276 
LYS   CD  HD2  sing N N 277 
LYS   CD  HD3  sing N N 278 
LYS   CE  NZ   sing N N 279 
LYS   CE  HE2  sing N N 280 
LYS   CE  HE3  sing N N 281 
LYS   NZ  HZ1  sing N N 282 
LYS   NZ  HZ2  sing N N 283 
LYS   NZ  HZ3  sing N N 284 
LYS   OXT HXT  sing N N 285 
MET   N   CA   sing N N 286 
MET   N   H    sing N N 287 
MET   N   H2   sing N N 288 
MET   CA  C    sing N N 289 
MET   CA  CB   sing N N 290 
MET   CA  HA   sing N N 291 
MET   C   O    doub N N 292 
MET   C   OXT  sing N N 293 
MET   CB  CG   sing N N 294 
MET   CB  HB2  sing N N 295 
MET   CB  HB3  sing N N 296 
MET   CG  SD   sing N N 297 
MET   CG  HG2  sing N N 298 
MET   CG  HG3  sing N N 299 
MET   SD  CE   sing N N 300 
MET   CE  HE1  sing N N 301 
MET   CE  HE2  sing N N 302 
MET   CE  HE3  sing N N 303 
MET   OXT HXT  sing N N 304 
PHE   N   CA   sing N N 305 
PHE   N   H    sing N N 306 
PHE   N   H2   sing N N 307 
PHE   CA  C    sing N N 308 
PHE   CA  CB   sing N N 309 
PHE   CA  HA   sing N N 310 
PHE   C   O    doub N N 311 
PHE   C   OXT  sing N N 312 
PHE   CB  CG   sing N N 313 
PHE   CB  HB2  sing N N 314 
PHE   CB  HB3  sing N N 315 
PHE   CG  CD1  doub Y N 316 
PHE   CG  CD2  sing Y N 317 
PHE   CD1 CE1  sing Y N 318 
PHE   CD1 HD1  sing N N 319 
PHE   CD2 CE2  doub Y N 320 
PHE   CD2 HD2  sing N N 321 
PHE   CE1 CZ   doub Y N 322 
PHE   CE1 HE1  sing N N 323 
PHE   CE2 CZ   sing Y N 324 
PHE   CE2 HE2  sing N N 325 
PHE   CZ  HZ   sing N N 326 
PHE   OXT HXT  sing N N 327 
PRO   N   CA   sing N N 328 
PRO   N   CD   sing N N 329 
PRO   N   H    sing N N 330 
PRO   CA  C    sing N N 331 
PRO   CA  CB   sing N N 332 
PRO   CA  HA   sing N N 333 
PRO   C   O    doub N N 334 
PRO   C   OXT  sing N N 335 
PRO   CB  CG   sing N N 336 
PRO   CB  HB2  sing N N 337 
PRO   CB  HB3  sing N N 338 
PRO   CG  CD   sing N N 339 
PRO   CG  HG2  sing N N 340 
PRO   CG  HG3  sing N N 341 
PRO   CD  HD2  sing N N 342 
PRO   CD  HD3  sing N N 343 
PRO   OXT HXT  sing N N 344 
SER   N   CA   sing N N 345 
SER   N   H    sing N N 346 
SER   N   H2   sing N N 347 
SER   CA  C    sing N N 348 
SER   CA  CB   sing N N 349 
SER   CA  HA   sing N N 350 
SER   C   O    doub N N 351 
SER   C   OXT  sing N N 352 
SER   CB  OG   sing N N 353 
SER   CB  HB2  sing N N 354 
SER   CB  HB3  sing N N 355 
SER   OG  HG   sing N N 356 
SER   OXT HXT  sing N N 357 
THR   N   CA   sing N N 358 
THR   N   H    sing N N 359 
THR   N   H2   sing N N 360 
THR   CA  C    sing N N 361 
THR   CA  CB   sing N N 362 
THR   CA  HA   sing N N 363 
THR   C   O    doub N N 364 
THR   C   OXT  sing N N 365 
THR   CB  OG1  sing N N 366 
THR   CB  CG2  sing N N 367 
THR   CB  HB   sing N N 368 
THR   OG1 HG1  sing N N 369 
THR   CG2 HG21 sing N N 370 
THR   CG2 HG22 sing N N 371 
THR   CG2 HG23 sing N N 372 
THR   OXT HXT  sing N N 373 
TRP   N   CA   sing N N 374 
TRP   N   H    sing N N 375 
TRP   N   H2   sing N N 376 
TRP   CA  C    sing N N 377 
TRP   CA  CB   sing N N 378 
TRP   CA  HA   sing N N 379 
TRP   C   O    doub N N 380 
TRP   C   OXT  sing N N 381 
TRP   CB  CG   sing N N 382 
TRP   CB  HB2  sing N N 383 
TRP   CB  HB3  sing N N 384 
TRP   CG  CD1  doub Y N 385 
TRP   CG  CD2  sing Y N 386 
TRP   CD1 NE1  sing Y N 387 
TRP   CD1 HD1  sing N N 388 
TRP   CD2 CE2  doub Y N 389 
TRP   CD2 CE3  sing Y N 390 
TRP   NE1 CE2  sing Y N 391 
TRP   NE1 HE1  sing N N 392 
TRP   CE2 CZ2  sing Y N 393 
TRP   CE3 CZ3  doub Y N 394 
TRP   CE3 HE3  sing N N 395 
TRP   CZ2 CH2  doub Y N 396 
TRP   CZ2 HZ2  sing N N 397 
TRP   CZ3 CH2  sing Y N 398 
TRP   CZ3 HZ3  sing N N 399 
TRP   CH2 HH2  sing N N 400 
TRP   OXT HXT  sing N N 401 
TYR   N   CA   sing N N 402 
TYR   N   H    sing N N 403 
TYR   N   H2   sing N N 404 
TYR   CA  C    sing N N 405 
TYR   CA  CB   sing N N 406 
TYR   CA  HA   sing N N 407 
TYR   C   O    doub N N 408 
TYR   C   OXT  sing N N 409 
TYR   CB  CG   sing N N 410 
TYR   CB  HB2  sing N N 411 
TYR   CB  HB3  sing N N 412 
TYR   CG  CD1  doub Y N 413 
TYR   CG  CD2  sing Y N 414 
TYR   CD1 CE1  sing Y N 415 
TYR   CD1 HD1  sing N N 416 
TYR   CD2 CE2  doub Y N 417 
TYR   CD2 HD2  sing N N 418 
TYR   CE1 CZ   doub Y N 419 
TYR   CE1 HE1  sing N N 420 
TYR   CE2 CZ   sing Y N 421 
TYR   CE2 HE2  sing N N 422 
TYR   CZ  OH   sing N N 423 
TYR   OH  HH   sing N N 424 
TYR   OXT HXT  sing N N 425 
VAL   N   CA   sing N N 426 
VAL   N   H    sing N N 427 
VAL   N   H2   sing N N 428 
VAL   CA  C    sing N N 429 
VAL   CA  CB   sing N N 430 
VAL   CA  HA   sing N N 431 
VAL   C   O    doub N N 432 
VAL   C   OXT  sing N N 433 
VAL   CB  CG1  sing N N 434 
VAL   CB  CG2  sing N N 435 
VAL   CB  HB   sing N N 436 
VAL   CG1 HG11 sing N N 437 
VAL   CG1 HG12 sing N N 438 
VAL   CG1 HG13 sing N N 439 
VAL   CG2 HG21 sing N N 440 
VAL   CG2 HG22 sing N N 441 
VAL   CG2 HG23 sing N N 442 
VAL   OXT HXT  sing N N 443 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Ministry of Science and Technology (MoST, China)'    China GZNL2023401008 1 
'Ministry of Science and Technology (MoST, China)'    China SRPG22-002     2 
'Ministry of Science and Technology (MoST, China)'    China SRPG22-003     3 
'National Natural Science Foundation of China (NSFC)' China 82170473       4 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7CJM 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8YX2 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.016493 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010171 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006864 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
H  
N  
O  
S  
ZN 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N    . GLU   A 1 2   ? 19.414  -6.590  -11.973 1.00 58.36  ?  1   GLU   B N    1 
ATOM   2     C  CA   . GLU   A 1 2   ? 20.421  -6.125  -11.027 1.00 46.61  ?  1   GLU   B CA   1 
ATOM   3     C  C    . GLU   A 1 2   ? 20.074  -4.833  -10.313 1.00 42.88  ?  1   GLU   B C    1 
ATOM   4     O  O    . GLU   A 1 2   ? 20.821  -4.406  -9.436  1.00 49.55  ?  1   GLU   B O    1 
ATOM   5     C  CB   . GLU   A 1 2   ? 21.754  -5.964  -11.767 1.00 40.67  ?  1   GLU   B CB   1 
ATOM   6     C  CG   . GLU   A 1 2   ? 22.157  -4.558  -12.191 1.00 37.86  ?  1   GLU   B CG   1 
ATOM   7     C  CD   . GLU   A 1 2   ? 23.674  -4.541  -12.488 1.00 64.29  ?  1   GLU   B CD   1 
ATOM   8     O  OE1  . GLU   A 1 2   ? 24.257  -5.650  -12.530 1.00 70.31  ?  1   GLU   B OE1  1 
ATOM   9     O  OE2  . GLU   A 1 2   ? 24.301  -3.463  -12.696 1.00 63.86  -1 1   GLU   B OE2  1 
ATOM   10    H  H    . GLU   A 1 2   ? 19.105  -5.976  -12.491 1.00 70.03  ?  1   GLU   B H    1 
ATOM   11    H  HA   . GLU   A 1 2   ? 20.491  -6.790  -10.324 1.00 55.93  ?  1   GLU   B HA   1 
ATOM   12    H  HB2  . GLU   A 1 2   ? 22.457  -6.294  -11.187 1.00 48.80  ?  1   GLU   B HB2  1 
ATOM   13    H  HB3  . GLU   A 1 2   ? 21.711  -6.499  -12.575 1.00 48.80  ?  1   GLU   B HB3  1 
ATOM   14    H  HG2  . GLU   A 1 2   ? 21.674  -4.303  -12.993 1.00 45.43  ?  1   GLU   B HG2  1 
ATOM   15    H  HG3  . GLU   A 1 2   ? 21.967  -3.930  -11.476 1.00 45.43  ?  1   GLU   B HG3  1 
ATOM   16    N  N    . VAL   A 1 3   ? 18.970  -4.198  -10.730 1.00 40.45  ?  2   VAL   B N    1 
ATOM   17    C  CA   . VAL   A 1 3   ? 18.308  -3.152  -9.955  1.00 38.57  ?  2   VAL   B CA   1 
ATOM   18    C  C    . VAL   A 1 3   ? 16.925  -3.675  -9.584  1.00 42.05  ?  2   VAL   B C    1 
ATOM   19    O  O    . VAL   A 1 3   ? 15.920  -3.311  -10.214 1.00 43.83  ?  2   VAL   B O    1 
ATOM   20    C  CB   . VAL   A 1 3   ? 18.228  -1.822  -10.714 1.00 38.38  ?  2   VAL   B CB   1 
ATOM   21    C  CG1  . VAL   A 1 3   ? 17.659  -0.766  -9.858  1.00 40.08  ?  2   VAL   B CG1  1 
ATOM   22    C  CG2  . VAL   A 1 3   ? 19.626  -1.416  -11.159 1.00 42.01  ?  2   VAL   B CG2  1 
ATOM   23    H  H    . VAL   A 1 3   ? 18.579  -4.362  -11.478 1.00 48.54  ?  2   VAL   B H    1 
ATOM   24    H  HA   . VAL   A 1 3   ? 18.814  -2.971  -9.148  1.00 46.28  ?  2   VAL   B HA   1 
ATOM   25    H  HB   . VAL   A 1 3   ? 17.653  -1.931  -11.487 1.00 46.06  ?  2   VAL   B HB   1 
ATOM   26    H  HG11 . VAL   A 1 3   ? 18.020  0.092   -10.133 1.00 48.10  ?  2   VAL   B HG11 1 
ATOM   27    H  HG12 . VAL   A 1 3   ? 16.694  -0.765  -9.957  1.00 48.10  ?  2   VAL   B HG12 1 
ATOM   28    H  HG13 . VAL   A 1 3   ? 17.897  -0.945  -8.935  1.00 48.10  ?  2   VAL   B HG13 1 
ATOM   29    H  HG21 . VAL   A 1 3   ? 19.573  -0.574  -11.637 1.00 50.41  ?  2   VAL   B HG21 1 
ATOM   30    H  HG22 . VAL   A 1 3   ? 20.190  -1.316  -10.376 1.00 50.41  ?  2   VAL   B HG22 1 
ATOM   31    H  HG23 . VAL   A 1 3   ? 19.985  -2.104  -11.740 1.00 50.41  ?  2   VAL   B HG23 1 
ATOM   32    N  N    . ARG   A 1 4   ? 16.876  -4.563  -8.581  1.00 38.98  ?  3   ARG   B N    1 
ATOM   33    C  CA   . ARG   A 1 4   ? 15.608  -4.982  -7.993  1.00 50.49  ?  3   ARG   B CA   1 
ATOM   34    C  C    . ARG   A 1 4   ? 15.094  -3.934  -6.993  1.00 53.95  ?  3   ARG   B C    1 
ATOM   35    O  O    . ARG   A 1 4   ? 15.844  -3.073  -6.501  1.00 49.82  ?  3   ARG   B O    1 
ATOM   36    C  CB   . ARG   A 1 4   ? 15.741  -6.335  -7.298  1.00 53.48  ?  3   ARG   B CB   1 
ATOM   37    C  CG   . ARG   A 1 4   ? 16.463  -7.432  -8.098  1.00 54.79  ?  3   ARG   B CG   1 
ATOM   38    C  CD   . ARG   A 1 4   ? 17.500  -8.194  -7.176  1.00 73.68  ?  3   ARG   B CD   1 
ATOM   39    N  NE   . ARG   A 1 4   ? 18.692  -7.394  -6.869  1.00 68.62  ?  3   ARG   B NE   1 
ATOM   40    C  CZ   . ARG   A 1 4   ? 19.353  -7.404  -5.715  1.00 69.92  ?  3   ARG   B CZ   1 
ATOM   41    N  NH1  . ARG   A 1 4   ? 19.005  -8.210  -4.719  1.00 70.31  ?  3   ARG   B NH1  1 
ATOM   42    N  NH2  . ARG   A 1 4   ? 20.378  -6.568  -5.546  1.00 66.99  ?  3   ARG   B NH2  1 
ATOM   43    H  H    . ARG   A 1 4   ? 17.566  -4.934  -8.226  1.00 46.78  ?  3   ARG   B H    1 
ATOM   44    H  HA   . ARG   A 1 4   ? 14.955  -5.073  -8.705  1.00 60.58  ?  3   ARG   B HA   1 
ATOM   45    H  HB2  . ARG   A 1 4   ? 16.238  -6.206  -6.475  1.00 64.18  ?  3   ARG   B HB2  1 
ATOM   46    H  HB3  . ARG   A 1 4   ? 14.850  -6.663  -7.100  1.00 64.18  ?  3   ARG   B HB3  1 
ATOM   47    H  HG2  . ARG   A 1 4   ? 15.815  -8.073  -8.430  1.00 65.75  ?  3   ARG   B HG2  1 
ATOM   48    H  HG3  . ARG   A 1 4   ? 16.944  -7.032  -8.840  1.00 65.75  ?  3   ARG   B HG3  1 
ATOM   49    H  HD2  . ARG   A 1 4   ? 17.069  -8.422  -6.338  1.00 88.42  ?  3   ARG   B HD2  1 
ATOM   50    H  HD3  . ARG   A 1 4   ? 17.791  -9.001  -7.629  1.00 88.42  ?  3   ARG   B HD3  1 
ATOM   51    H  HE   . ARG   A 1 4   ? 18.988  -6.875  -7.488  1.00 82.34  ?  3   ARG   B HE   1 
ATOM   52    H  HH11 . ARG   A 1 4   ? 18.337  -8.743  -4.811  1.00 84.37  ?  3   ARG   B HH11 1 
ATOM   53    H  HH12 . ARG   A 1 4   ? 19.448  -8.198  -3.982  1.00 84.37  ?  3   ARG   B HH12 1 
ATOM   54    H  HH21 . ARG   A 1 4   ? 20.603  -6.031  -6.179  1.00 80.38  ?  3   ARG   B HH21 1 
ATOM   55    H  HH22 . ARG   A 1 4   ? 20.813  -6.565  -4.804  1.00 80.38  ?  3   ARG   B HH22 1 
ATOM   56    N  N    . THR   A 1 5   ? 13.784  -4.004  -6.714  1.00 56.11  ?  4   THR   B N    1 
ATOM   57    C  CA   . THR   A 1 5   ? 13.149  -3.151  -5.715  1.00 59.78  ?  4   THR   B CA   1 
ATOM   58    C  C    . THR   A 1 5   ? 12.116  -3.942  -4.924  1.00 59.45  ?  4   THR   B C    1 
ATOM   59    O  O    . THR   A 1 5   ? 11.515  -4.891  -5.440  1.00 51.51  ?  4   THR   B O    1 
ATOM   60    C  CB   . THR   A 1 5   ? 12.423  -1.944  -6.320  1.00 51.45  ?  4   THR   B CB   1 
ATOM   61    O  OG1  . THR   A 1 5   ? 11.218  -2.409  -6.941  1.00 53.19  ?  4   THR   B OG1  1 
ATOM   62    C  CG2  . THR   A 1 5   ? 13.297  -1.241  -7.325  1.00 57.79  ?  4   THR   B CG2  1 
ATOM   63    H  H    . THR   A 1 5   ? 13.239  -4.547  -7.099  1.00 67.33  ?  4   THR   B H    1 
ATOM   64    H  HA   . THR   A 1 5   ? 13.854  -2.841  -5.126  1.00 71.74  ?  4   THR   B HA   1 
ATOM   65    H  HB   . THR   A 1 5   ? 12.208  -1.296  -5.631  1.00 61.74  ?  4   THR   B HB   1 
ATOM   66    H  HG1  . THR   A 1 5   ? 11.395  -3.021  -7.489  1.00 63.83  ?  4   THR   B HG1  1 
ATOM   67    H  HG21 . THR   A 1 5   ? 12.862  -0.431  -7.634  1.00 69.35  ?  4   THR   B HG21 1 
ATOM   68    H  HG22 . THR   A 1 5   ? 14.147  -1.006  -6.919  1.00 69.35  ?  4   THR   B HG22 1 
ATOM   69    H  HG23 . THR   A 1 5   ? 13.461  -1.820  -8.085  1.00 69.35  ?  4   THR   B HG23 1 
ATOM   70    N  N    . ILE   A 1 6   ? 11.897  -3.512  -3.667  1.00 62.09  ?  5   ILE   B N    1 
ATOM   71    C  CA   . ILE   A 1 6   ? 10.804  -3.999  -2.826  1.00 55.80  ?  5   ILE   B CA   1 
ATOM   72    C  C    . ILE   A 1 6   ? 9.993   -2.801  -2.329  1.00 48.26  ?  5   ILE   B C    1 
ATOM   73    O  O    . ILE   A 1 6   ? 10.462  -1.660  -2.314  1.00 45.69  ?  5   ILE   B O    1 
ATOM   74    C  CB   . ILE   A 1 6   ? 11.276  -4.853  -1.625  1.00 53.63  ?  5   ILE   B CB   1 
ATOM   75    C  CG1  . ILE   A 1 6   ? 12.231  -4.079  -0.703  1.00 48.26  ?  5   ILE   B CG1  1 
ATOM   76    C  CG2  . ILE   A 1 6   ? 12.005  -6.120  -2.079  1.00 57.11  ?  5   ILE   B CG2  1 
ATOM   77    C  CD1  . ILE   A 1 6   ? 12.622  -4.827  0.572   1.00 48.27  ?  5   ILE   B CD1  1 
ATOM   78    H  H    . ILE   A 1 6   ? 12.385  -2.923  -3.275  1.00 74.51  ?  5   ILE   B H    1 
ATOM   79    H  HA   . ILE   A 1 6   ? 10.235  -4.560  -3.378  1.00 66.96  ?  5   ILE   B HA   1 
ATOM   80    H  HB   . ILE   A 1 6   ? 10.466  -5.084  -1.143  1.00 64.36  ?  5   ILE   B HB   1 
ATOM   81    H  HG12 . ILE   A 1 6   ? 13.046  -3.887  -1.193  1.00 57.91  ?  5   ILE   B HG12 1 
ATOM   82    H  HG13 . ILE   A 1 6   ? 11.800  -3.251  -0.437  1.00 57.91  ?  5   ILE   B HG13 1 
ATOM   83    H  HG21 . ILE   A 1 6   ? 12.240  -6.646  -1.299  1.00 68.53  ?  5   ILE   B HG21 1 
ATOM   84    H  HG22 . ILE   A 1 6   ? 11.419  -6.631  -2.659  1.00 68.53  ?  5   ILE   B HG22 1 
ATOM   85    H  HG23 . ILE   A 1 6   ? 12.808  -5.866  -2.561  1.00 68.53  ?  5   ILE   B HG23 1 
ATOM   86    H  HD11 . ILE   A 1 6   ? 13.157  -4.242  1.130   1.00 57.93  ?  5   ILE   B HD11 1 
ATOM   87    H  HD12 . ILE   A 1 6   ? 11.816  -5.089  1.044   1.00 57.93  ?  5   ILE   B HD12 1 
ATOM   88    H  HD13 . ILE   A 1 6   ? 13.135  -5.614  0.331   1.00 57.93  ?  5   ILE   B HD13 1 
ATOM   89    N  N    . LYS   A 1 7   ? 8.741   -3.068  -1.952  1.00 49.99  ?  6   LYS   B N    1 
ATOM   90    C  CA   . LYS   A 1 7   ? 7.864   -2.069  -1.339  1.00 48.36  ?  6   LYS   B CA   1 
ATOM   91    C  C    . LYS   A 1 7   ? 7.902   -2.265  0.173   1.00 39.07  ?  6   LYS   B C    1 
ATOM   92    O  O    . LYS   A 1 7   ? 7.861   -3.405  0.651   1.00 32.47  ?  6   LYS   B O    1 
ATOM   93    C  CB   . LYS   A 1 7   ? 6.432   -2.187  -1.862  1.00 57.61  ?  6   LYS   B CB   1 
ATOM   94    C  CG   . LYS   A 1 7   ? 6.060   -1.137  -2.938  1.00 64.11  ?  6   LYS   B CG   1 
ATOM   95    C  CD   . LYS   A 1 7   ? 5.061   -1.680  -3.994  1.00 61.74  ?  6   LYS   B CD   1 
ATOM   96    C  CE   . LYS   A 1 7   ? 4.138   -0.587  -4.536  1.00 62.79  ?  6   LYS   B CE   1 
ATOM   97    N  NZ   . LYS   A 1 7   ? 2.835   -1.116  -5.039  1.00 67.51  ?  6   LYS   B NZ   1 
ATOM   98    H  H    . LYS   A 1 7   ? 8.370   -3.838  -2.043  1.00 59.99  ?  6   LYS   B H    1 
ATOM   99    H  HA   . LYS   A 1 7   ? 8.174   -1.175  -1.553  1.00 58.03  ?  6   LYS   B HA   1 
ATOM   100   H  HB2  . LYS   A 1 7   ? 6.318   -3.066  -2.256  1.00 69.14  ?  6   LYS   B HB2  1 
ATOM   101   H  HB3  . LYS   A 1 7   ? 5.820   -2.075  -1.118  1.00 69.14  ?  6   LYS   B HB3  1 
ATOM   102   H  HG2  . LYS   A 1 7   ? 5.650   -0.372  -2.505  1.00 76.93  ?  6   LYS   B HG2  1 
ATOM   103   H  HG3  . LYS   A 1 7   ? 6.866   -0.863  -3.404  1.00 76.93  ?  6   LYS   B HG3  1 
ATOM   104   H  HD2  . LYS   A 1 7   ? 5.556   -2.053  -4.739  1.00 74.09  ?  6   LYS   B HD2  1 
ATOM   105   H  HD3  . LYS   A 1 7   ? 4.508   -2.365  -3.586  1.00 74.09  ?  6   LYS   B HD3  1 
ATOM   106   H  HE2  . LYS   A 1 7   ? 3.949   0.047   -3.827  1.00 75.35  ?  6   LYS   B HE2  1 
ATOM   107   H  HE3  . LYS   A 1 7   ? 4.582   -0.137  -5.273  1.00 75.35  ?  6   LYS   B HE3  1 
ATOM   108   H  HZ1  . LYS   A 1 7   ? 2.330   -0.447  -5.338  1.00 81.02  ?  6   LYS   B HZ1  1 
ATOM   109   H  HZ2  . LYS   A 1 7   ? 2.976   -1.691  -5.704  1.00 81.02  ?  6   LYS   B HZ2  1 
ATOM   110   H  HZ3  . LYS   A 1 7   ? 2.403   -1.533  -4.383  1.00 81.02  ?  6   LYS   B HZ3  1 
ATOM   111   N  N    . VAL   A 1 8   ? 8.092   -1.172  0.918   1.00 39.32  ?  7   VAL   B N    1 
ATOM   112   C  CA   . VAL   A 1 8   ? 8.028   -1.202  2.379   1.00 41.48  ?  7   VAL   B CA   1 
ATOM   113   C  C    . VAL   A 1 8   ? 7.240   0.003   2.891   1.00 39.68  ?  7   VAL   B C    1 
ATOM   114   O  O    . VAL   A 1 8   ? 6.943   0.949   2.157   1.00 40.29  ?  7   VAL   B O    1 
ATOM   115   C  CB   . VAL   A 1 8   ? 9.419   -1.205  3.059   1.00 30.77  ?  7   VAL   B CB   1 
ATOM   116   C  CG1  . VAL   A 1 8   ? 10.330  -2.262  2.473   1.00 39.15  ?  7   VAL   B CG1  1 
ATOM   117   C  CG2  . VAL   A 1 8   ? 10.042  0.189   2.975   1.00 36.42  ?  7   VAL   B CG2  1 
ATOM   118   H  H    . VAL   A 1 8   ? 8.262   -0.394  0.594   1.00 47.18  ?  7   VAL   B H    1 
ATOM   119   H  HA   . VAL   A 1 8   ? 7.554   -2.014  2.619   1.00 49.78  ?  7   VAL   B HA   1 
ATOM   120   H  HB   . VAL   A 1 8   ? 9.309   -1.433  3.996   1.00 36.93  ?  7   VAL   B HB   1 
ATOM   121   H  HG11 . VAL   A 1 8   ? 11.033  -2.463  3.111   1.00 46.99  ?  7   VAL   B HG11 1 
ATOM   122   H  HG12 . VAL   A 1 8   ? 9.810   -3.061  2.291   1.00 46.99  ?  7   VAL   B HG12 1 
ATOM   123   H  HG13 . VAL   A 1 8   ? 10.717  -1.925  1.650   1.00 46.99  ?  7   VAL   B HG13 1 
ATOM   124   H  HG21 . VAL   A 1 8   ? 11.005  0.110   3.063   1.00 43.70  ?  7   VAL   B HG21 1 
ATOM   125   H  HG22 . VAL   A 1 8   ? 9.819   0.583   2.118   1.00 43.70  ?  7   VAL   B HG22 1 
ATOM   126   H  HG23 . VAL   A 1 8   ? 9.688   0.737   3.693   1.00 43.70  ?  7   VAL   B HG23 1 
ATOM   127   N  N    . PHE   A 1 9   ? 6.954   -0.009  4.196   1.00 42.40  ?  8   PHE   B N    1 
ATOM   128   C  CA   . PHE   A 1 9   ? 6.317   1.130   4.857   1.00 43.29  ?  8   PHE   B CA   1 
ATOM   129   C  C    . PHE   A 1 9   ? 7.325   1.858   5.746   1.00 33.30  ?  8   PHE   B C    1 
ATOM   130   O  O    . PHE   A 1 9   ? 8.106   1.225   6.462   1.00 37.22  ?  8   PHE   B O    1 
ATOM   131   C  CB   . PHE   A 1 9   ? 5.099   0.706   5.716   1.00 41.22  ?  8   PHE   B CB   1 
ATOM   132   C  CG   . PHE   A 1 9   ? 4.030   -0.062  4.953   1.00 37.09  ?  8   PHE   B CG   1 
ATOM   133   C  CD1  . PHE   A 1 9   ? 3.108   0.588   4.180   1.00 35.21  ?  8   PHE   B CD1  1 
ATOM   134   C  CD2  . PHE   A 1 9   ? 3.935   -1.427  5.068   1.00 40.39  ?  8   PHE   B CD2  1 
ATOM   135   C  CE1  . PHE   A 1 9   ? 2.166   -0.115  3.481   1.00 31.35  ?  8   PHE   B CE1  1 
ATOM   136   C  CE2  . PHE   A 1 9   ? 2.986   -2.128  4.386   1.00 30.60  ?  8   PHE   B CE2  1 
ATOM   137   C  CZ   . PHE   A 1 9   ? 2.115   -1.471  3.575   1.00 32.65  ?  8   PHE   B CZ   1 
ATOM   138   H  H    . PHE   A 1 9   ? 7.120   -0.670  4.721   1.00 50.88  ?  8   PHE   B H    1 
ATOM   139   H  HA   . PHE   A 1 9   ? 6.003   1.739   4.171   1.00 51.95  ?  8   PHE   B HA   1 
ATOM   140   H  HB2  . PHE   A 1 9   ? 5.412   0.136   6.437   1.00 49.47  ?  8   PHE   B HB2  1 
ATOM   141   H  HB3  . PHE   A 1 9   ? 4.684   1.504   6.081   1.00 49.47  ?  8   PHE   B HB3  1 
ATOM   142   H  HD1  . PHE   A 1 9   ? 3.123   1.517   4.129   1.00 42.25  ?  8   PHE   B HD1  1 
ATOM   143   H  HD2  . PHE   A 1 9   ? 4.530   -1.881  5.620   1.00 48.47  ?  8   PHE   B HD2  1 
ATOM   144   H  HE1  . PHE   A 1 9   ? 1.558   0.336   2.940   1.00 37.62  ?  8   PHE   B HE1  1 
ATOM   145   H  HE2  . PHE   A 1 9   ? 2.934   -3.052  4.476   1.00 36.72  ?  8   PHE   B HE2  1 
ATOM   146   H  HZ   . PHE   A 1 9   ? 1.485   -1.949  3.085   1.00 39.18  ?  8   PHE   B HZ   1 
ATOM   147   N  N    . THR   A 1 10  ? 7.274   3.189   5.727   1.00 35.41  ?  9   THR   B N    1 
ATOM   148   C  CA   . THR   A 1 10  ? 7.991   4.034   6.666   1.00 30.15  ?  9   THR   B CA   1 
ATOM   149   C  C    . THR   A 1 10  ? 7.002   4.776   7.551   1.00 42.54  ?  9   THR   B C    1 
ATOM   150   O  O    . THR   A 1 10  ? 5.837   4.992   7.193   1.00 37.82  ?  9   THR   B O    1 
ATOM   151   C  CB   . THR   A 1 10  ? 8.881   5.060   5.955   1.00 35.96  ?  9   THR   B CB   1 
ATOM   152   O  OG1  . THR   A 1 10  ? 8.075   5.804   5.028   1.00 45.09  ?  9   THR   B OG1  1 
ATOM   153   C  CG2  . THR   A 1 10  ? 9.979   4.356   5.236   1.00 34.77  ?  9   THR   B CG2  1 
ATOM   154   H  H    . THR   A 1 10  ? 6.812   3.638   5.156   1.00 42.50  ?  9   THR   B H    1 
ATOM   155   H  HA   . THR   A 1 10  ? 8.559   3.469   7.213   1.00 36.18  ?  9   THR   B HA   1 
ATOM   156   H  HB   . THR   A 1 10  ? 9.282   5.673   6.592   1.00 43.15  ?  9   THR   B HB   1 
ATOM   157   H  HG1  . THR   A 1 10  ? 7.457   6.200   5.437   1.00 54.11  ?  9   THR   B HG1  1 
ATOM   158   H  HG21 . THR   A 1 10  ? 10.487  4.990   4.705   1.00 41.73  ?  9   THR   B HG21 1 
ATOM   159   H  HG22 . THR   A 1 10  ? 10.575  3.932   5.873   1.00 41.73  ?  9   THR   B HG22 1 
ATOM   160   H  HG23 . THR   A 1 10  ? 9.611   3.678   4.649   1.00 41.73  ?  9   THR   B HG23 1 
ATOM   161   N  N    . THR   A 1 11  ? 7.505   5.223   8.693   1.00 38.10  ?  10  THR   B N    1 
ATOM   162   C  CA   . THR   A 1 11  ? 6.643   5.759   9.727   1.00 37.11  ?  10  THR   B CA   1 
ATOM   163   C  C    . THR   A 1 11  ? 7.512   6.510   10.709  1.00 41.79  ?  10  THR   B C    1 
ATOM   164   O  O    . THR   A 1 11  ? 8.711   6.314   10.734  1.00 37.05  ?  10  THR   B O    1 
ATOM   165   C  CB   . THR   A 1 11  ? 5.883   4.643   10.449  1.00 34.49  ?  10  THR   B CB   1 
ATOM   166   O  OG1  . THR   A 1 11  ? 4.870   5.247   11.263  1.00 37.70  ?  10  THR   B OG1  1 
ATOM   167   C  CG2  . THR   A 1 11  ? 6.837   3.808   11.284  1.00 41.24  ?  10  THR   B CG2  1 
ATOM   168   H  H    . THR   A 1 11  ? 8.342   5.226   8.890   1.00 45.72  ?  10  THR   B H    1 
ATOM   169   H  HA   . THR   A 1 11  ? 6.000   6.372   9.337   1.00 44.53  ?  10  THR   B HA   1 
ATOM   170   H  HB   . THR   A 1 11  ? 5.464   4.038   9.817   1.00 41.39  ?  10  THR   B HB   1 
ATOM   171   H  HG1  . THR   A 1 11  ? 4.454   5.827   10.821  1.00 45.24  ?  10  THR   B HG1  1 
ATOM   172   H  HG21 . THR   A 1 11  ? 6.397   2.995   11.577  1.00 49.49  ?  10  THR   B HG21 1 
ATOM   173   H  HG22 . THR   A 1 11  ? 7.618   3.572   10.759  1.00 49.49  ?  10  THR   B HG22 1 
ATOM   174   H  HG23 . THR   A 1 11  ? 7.122   4.310   12.064  1.00 49.49  ?  10  THR   B HG23 1 
ATOM   175   N  N    . VAL   A 1 12  ? 6.888   7.359   11.515  1.00 39.70  ?  11  VAL   B N    1 
ATOM   176   C  CA   . VAL   A 1 12  ? 7.500   7.893   12.724  1.00 39.74  ?  11  VAL   B CA   1 
ATOM   177   C  C    . VAL   A 1 12  ? 6.748   7.517   13.985  1.00 37.10  ?  11  VAL   B C    1 
ATOM   178   O  O    . VAL   A 1 12  ? 7.266   7.755   15.080  1.00 43.87  ?  11  VAL   B O    1 
ATOM   179   C  CB   . VAL   A 1 12  ? 7.640   9.425   12.653  1.00 38.24  ?  11  VAL   B CB   1 
ATOM   180   C  CG1  . VAL   A 1 12  ? 8.709   9.742   11.660  1.00 48.62  ?  11  VAL   B CG1  1 
ATOM   181   C  CG2  . VAL   A 1 12  ? 6.379   10.085  12.258  1.00 43.06  ?  11  VAL   B CG2  1 
ATOM   182   H  H    . VAL   A 1 12  ? 6.090   7.648   11.380  1.00 47.64  ?  11  VAL   B H    1 
ATOM   183   H  HA   . VAL   A 1 12  ? 8.390   7.514   12.795  1.00 47.69  ?  11  VAL   B HA   1 
ATOM   184   H  HB   . VAL   A 1 12  ? 7.867   9.765   13.533  1.00 45.89  ?  11  VAL   B HB   1 
ATOM   185   H  HG11 . VAL   A 1 12  ? 8.685   10.691  11.461  1.00 58.34  ?  11  VAL   B HG11 1 
ATOM   186   H  HG12 . VAL   A 1 12  ? 9.571   9.504   12.037  1.00 58.34  ?  11  VAL   B HG12 1 
ATOM   187   H  HG13 . VAL   A 1 12  ? 8.550   9.230   10.851  1.00 58.34  ?  11  VAL   B HG13 1 
ATOM   188   H  HG21 . VAL   A 1 12  ? 6.477   11.044  12.365  1.00 51.67  ?  11  VAL   B HG21 1 
ATOM   189   H  HG22 . VAL   A 1 12  ? 6.188   9.873   11.331  1.00 51.67  ?  11  VAL   B HG22 1 
ATOM   190   H  HG23 . VAL   A 1 12  ? 5.661   9.761   12.826  1.00 51.67  ?  11  VAL   B HG23 1 
ATOM   191   N  N    . ASP   A 1 13  ? 5.558   6.936   13.872  1.00 38.29  ?  12  ASP   B N    1 
ATOM   192   C  CA   . ASP   A 1 13  ? 4.658   6.758   14.992  1.00 36.19  ?  12  ASP   B CA   1 
ATOM   193   C  C    . ASP   A 1 13  ? 3.970   5.395   14.961  1.00 42.27  ?  12  ASP   B C    1 
ATOM   194   O  O    . ASP   A 1 13  ? 3.169   5.079   15.862  1.00 41.39  ?  12  ASP   B O    1 
ATOM   195   C  CB   . ASP   A 1 13  ? 3.605   7.886   14.986  1.00 36.36  ?  12  ASP   B CB   1 
ATOM   196   C  CG   . ASP   A 1 13  ? 2.797   7.942   13.687  1.00 48.34  ?  12  ASP   B CG   1 
ATOM   197   O  OD1  . ASP   A 1 13  ? 2.104   8.977   13.465  1.00 40.08  ?  12  ASP   B OD1  1 
ATOM   198   O  OD2  . ASP   A 1 13  ? 2.794   6.929   12.936  1.00 44.11  -1 12  ASP   B OD2  1 
ATOM   199   H  H    . ASP   A 1 13  ? 5.243   6.630   13.132  1.00 45.95  ?  12  ASP   B H    1 
ATOM   200   H  HA   . ASP   A 1 13  ? 5.142   6.822   15.830  1.00 43.43  ?  12  ASP   B HA   1 
ATOM   201   H  HB2  . ASP   A 1 13  ? 2.985   7.742   15.718  1.00 43.63  ?  12  ASP   B HB2  1 
ATOM   202   H  HB3  . ASP   A 1 13  ? 4.056   8.738   15.095  1.00 43.63  ?  12  ASP   B HB3  1 
ATOM   203   N  N    . ASN   A 1 14  ? 4.272   4.576   13.966  1.00 40.97  ?  13  ASN   B N    1 
ATOM   204   C  CA   . ASN   A 1 14  ? 3.645   3.287   13.741  1.00 38.76  ?  13  ASN   B CA   1 
ATOM   205   C  C    . ASN   A 1 14  ? 2.116   3.367   13.677  1.00 35.44  ?  13  ASN   B C    1 
ATOM   206   O  O    . ASN   A 1 14  ? 1.415   2.334   13.727  1.00 35.35  ?  13  ASN   B O    1 
ATOM   207   C  CB   . ASN   A 1 14  ? 4.109   2.296   14.798  1.00 30.50  ?  13  ASN   B CB   1 
ATOM   208   C  CG   . ASN   A 1 14  ? 4.275   0.910   14.245  1.00 41.73  ?  13  ASN   B CG   1 
ATOM   209   O  OD1  . ASN   A 1 14  ? 3.720   0.582   13.209  1.00 55.22  ?  13  ASN   B OD1  1 
ATOM   210   N  ND2  . ASN   A 1 14  ? 5.055   0.097   14.913  1.00 50.18  ?  13  ASN   B ND2  1 
ATOM   211   H  H    . ASN   A 1 14  ? 4.871   4.756   13.376  1.00 49.17  ?  13  ASN   B H    1 
ATOM   212   H  HA   . ASN   A 1 14  ? 3.918   2.952   12.873  1.00 46.51  ?  13  ASN   B HA   1 
ATOM   213   H  HB2  . ASN   A 1 14  ? 4.964   2.585   15.151  1.00 36.60  ?  13  ASN   B HB2  1 
ATOM   214   H  HB3  . ASN   A 1 14  ? 3.451   2.260   15.510  1.00 36.60  ?  13  ASN   B HB3  1 
ATOM   215   H  HD21 . ASN   A 1 14  ? 5.443   0.366   15.632  1.00 60.22  ?  13  ASN   B HD21 1 
ATOM   216   H  HD22 . ASN   A 1 14  ? 5.179   -0.707  14.633  1.00 60.22  ?  13  ASN   B HD22 1 
ATOM   217   N  N    . ILE   A 1 15  ? 1.556   4.552   13.455  1.00 38.05  ?  14  ILE   B N    1 
ATOM   218   C  CA   . ILE   A 1 15  ? 0.123   4.692   13.260  1.00 40.90  ?  14  ILE   B CA   1 
ATOM   219   C  C    . ILE   A 1 15  ? -0.214  5.268   11.886  1.00 36.63  ?  14  ILE   B C    1 
ATOM   220   O  O    . ILE   A 1 15  ? -1.138  4.797   11.236  1.00 36.55  ?  14  ILE   B O    1 
ATOM   221   C  CB   . ILE   A 1 15  ? -0.512  5.515   14.410  1.00 36.00  ?  14  ILE   B CB   1 
ATOM   222   C  CG1  . ILE   A 1 15  ? -2.045  5.642   14.209  1.00 55.06  ?  14  ILE   B CG1  1 
ATOM   223   C  CG2  . ILE   A 1 15  ? 0.066   6.900   14.517  1.00 41.33  ?  14  ILE   B CG2  1 
ATOM   224   C  CD1  . ILE   A 1 15  ? -2.764  6.653   15.158  1.00 69.47  ?  14  ILE   B CD1  1 
ATOM   225   H  H    . ILE   A 1 15  ? 1.992   5.292   13.413  1.00 45.66  ?  14  ILE   B H    1 
ATOM   226   H  HA   . ILE   A 1 15  ? -0.287  3.813   13.283  1.00 49.08  ?  14  ILE   B HA   1 
ATOM   227   H  HB   . ILE   A 1 15  ? -0.313  5.030   15.227  1.00 43.20  ?  14  ILE   B HB   1 
ATOM   228   H  HG12 . ILE   A 1 15  ? -2.210  5.933   13.299  1.00 66.07  ?  14  ILE   B HG12 1 
ATOM   229   H  HG13 . ILE   A 1 15  ? -2.446  4.771   14.357  1.00 66.07  ?  14  ILE   B HG13 1 
ATOM   230   H  HG21 . ILE   A 1 15  ? -0.366  7.367   15.250  1.00 49.60  ?  14  ILE   B HG21 1 
ATOM   231   H  HG22 . ILE   A 1 15  ? 1.019   6.833   14.684  1.00 49.60  ?  14  ILE   B HG22 1 
ATOM   232   H  HG23 . ILE   A 1 15  ? -0.091  7.373   13.685  1.00 49.60  ?  14  ILE   B HG23 1 
ATOM   233   H  HD11 . ILE   A 1 15  ? -3.713  6.658   14.953  1.00 83.37  ?  14  ILE   B HD11 1 
ATOM   234   H  HD12 . ILE   A 1 15  ? -2.626  6.376   16.078  1.00 83.37  ?  14  ILE   B HD12 1 
ATOM   235   H  HD13 . ILE   A 1 15  ? -2.391  7.537   15.019  1.00 83.37  ?  14  ILE   B HD13 1 
ATOM   236   N  N    . ASN   A 1 16  ? 0.574   6.200   11.378  1.00 37.67  ?  15  ASN   B N    1 
ATOM   237   C  CA   . ASN   A 1 16  ? 0.526   6.604   9.978   1.00 44.32  ?  15  ASN   B CA   1 
ATOM   238   C  C    . ASN   A 1 16  ? 1.650   5.940   9.193   1.00 41.95  ?  15  ASN   B C    1 
ATOM   239   O  O    . ASN   A 1 16  ? 2.833   6.226   9.423   1.00 43.84  ?  15  ASN   B O    1 
ATOM   240   C  CB   . ASN   A 1 16  ? 0.613   8.119   9.884   1.00 45.52  ?  15  ASN   B CB   1 
ATOM   241   C  CG   . ASN   A 1 16  ? -0.567  8.796   10.562  1.00 51.26  ?  15  ASN   B CG   1 
ATOM   242   O  OD1  . ASN   A 1 16  ? -1.712  8.716   10.103  1.00 51.46  ?  15  ASN   B OD1  1 
ATOM   243   N  ND2  . ASN   A 1 16  ? -0.294  9.446   11.673  1.00 49.76  ?  15  ASN   B ND2  1 
ATOM   244   H  H    . ASN   A 1 16  ? 1.163   6.627   11.836  1.00 45.20  ?  15  ASN   B H    1 
ATOM   245   H  HA   . ASN   A 1 16  ? -0.307  6.295   9.589   1.00 53.18  ?  15  ASN   B HA   1 
ATOM   246   H  HB2  . ASN   A 1 16  ? 1.426   8.420   10.318  1.00 54.63  ?  15  ASN   B HB2  1 
ATOM   247   H  HB3  . ASN   A 1 16  ? 0.618   8.381   8.950   1.00 54.63  ?  15  ASN   B HB3  1 
ATOM   248   H  HD21 . ASN   A 1 16  ? -0.922  9.849   12.101  1.00 59.72  ?  15  ASN   B HD21 1 
ATOM   249   H  HD22 . ASN   A 1 16  ? 0.512   9.468   11.971  1.00 59.72  ?  15  ASN   B HD22 1 
ATOM   250   N  N    . LEU   A 1 17  ? 1.277   5.053   8.270   1.00 35.56  ?  16  LEU   B N    1 
ATOM   251   C  CA   . LEU   A 1 17  ? 2.239   4.354   7.420   1.00 38.08  ?  16  LEU   B CA   1 
ATOM   252   C  C    . LEU   A 1 17  ? 2.348   5.007   6.049   1.00 38.69  ?  16  LEU   B C    1 
ATOM   253   O  O    . LEU   A 1 17  ? 1.357   5.510   5.519   1.00 34.01  ?  16  LEU   B O    1 
ATOM   254   C  CB   . LEU   A 1 17  ? 1.847   2.894   7.242   1.00 34.85  ?  16  LEU   B CB   1 
ATOM   255   C  CG   . LEU   A 1 17  ? 1.573   2.136   8.540   1.00 42.06  ?  16  LEU   B CG   1 
ATOM   256   C  CD1  . LEU   A 1 17  ? 1.483   0.657   8.190   1.00 45.14  ?  16  LEU   B CD1  1 
ATOM   257   C  CD2  . LEU   A 1 17  ? 2.680   2.391   9.545   1.00 43.38  ?  16  LEU   B CD2  1 
ATOM   258   H  H    . LEU   A 1 17  ? 0.459   4.836   8.115   1.00 42.67  ?  16  LEU   B H    1 
ATOM   259   H  HA   . LEU   A 1 17  ? 3.109   4.404   7.846   1.00 45.70  ?  16  LEU   B HA   1 
ATOM   260   H  HB2  . LEU   A 1 17  ? 1.039   2.857   6.706   1.00 41.82  ?  16  LEU   B HB2  1 
ATOM   261   H  HB3  . LEU   A 1 17  ? 2.569   2.436   6.784   1.00 41.82  ?  16  LEU   B HB3  1 
ATOM   262   H  HG   . LEU   A 1 17  ? 0.745   2.429   8.954   1.00 50.47  ?  16  LEU   B HG   1 
ATOM   263   H  HD11 . LEU   A 1 17  ? 1.194   0.164   8.973   1.00 54.17  ?  16  LEU   B HD11 1 
ATOM   264   H  HD12 . LEU   A 1 17  ? 0.841   0.541   7.471   1.00 54.17  ?  16  LEU   B HD12 1 
ATOM   265   H  HD13 . LEU   A 1 17  ? 2.356   0.346   7.906   1.00 54.17  ?  16  LEU   B HD13 1 
ATOM   266   H  HD21 . LEU   A 1 17  ? 2.688   1.671   10.195  1.00 52.06  ?  16  LEU   B HD21 1 
ATOM   267   H  HD22 . LEU   A 1 17  ? 3.529   2.423   9.077   1.00 52.06  ?  16  LEU   B HD22 1 
ATOM   268   H  HD23 . LEU   A 1 17  ? 2.515   3.237   9.989   1.00 52.06  ?  16  LEU   B HD23 1 
ATOM   269   N  N    . HIS   A 1 18  ? 3.560   5.029   5.488   1.00 36.30  ?  17  HIS   B N    1 
ATOM   270   C  CA   . HIS   A 1 18  ? 3.795   5.630   4.177   1.00 39.35  ?  17  HIS   B CA   1 
ATOM   271   C  C    . HIS   A 1 18  ? 4.509   4.629   3.289   1.00 37.86  ?  17  HIS   B C    1 
ATOM   272   O  O    . HIS   A 1 18  ? 5.586   4.134   3.650   1.00 37.56  ?  17  HIS   B O    1 
ATOM   273   C  CB   . HIS   A 1 18  ? 4.621   6.906   4.272   1.00 35.15  ?  17  HIS   B CB   1 
ATOM   274   C  CG   . HIS   A 1 18  ? 4.139   7.866   5.312   1.00 41.41  ?  17  HIS   B CG   1 
ATOM   275   N  ND1  . HIS   A 1 18  ? 3.387   8.979   5.004   1.00 45.48  ?  17  HIS   B ND1  1 
ATOM   276   C  CD2  . HIS   A 1 18  ? 4.317   7.895   6.654   1.00 44.36  ?  17  HIS   B CD2  1 
ATOM   277   C  CE1  . HIS   A 1 18  ? 3.117   9.651   6.108   1.00 52.55  ?  17  HIS   B CE1  1 
ATOM   278   N  NE2  . HIS   A 1 18  ? 3.657   9.005   7.127   1.00 53.68  ?  17  HIS   B NE2  1 
ATOM   279   H  H    . HIS   A 1 18  ? 4.265   4.698   5.852   1.00 43.56  ?  17  HIS   B H    1 
ATOM   280   H  HA   . HIS   A 1 18  ? 2.935   5.845   3.784   1.00 47.22  ?  17  HIS   B HA   1 
ATOM   281   H  HB2  . HIS   A 1 18  ? 5.536   6.669   4.492   1.00 42.18  ?  17  HIS   B HB2  1 
ATOM   282   H  HB3  . HIS   A 1 18  ? 4.592   7.360   3.416   1.00 42.18  ?  17  HIS   B HB3  1 
ATOM   283   H  HD2  . HIS   A 1 18  ? 4.796   7.279   7.161   1.00 53.23  ?  17  HIS   B HD2  1 
ATOM   284   H  HE1  . HIS   A 1 18  ? 2.630   10.442  6.159   1.00 63.06  ?  17  HIS   B HE1  1 
ATOM   285   H  HE2  . HIS   A 1 18  ? 3.604   9.241   7.953   1.00 64.41  ?  17  HIS   B HE2  1 
ATOM   286   N  N    . THR   A 1 19  ? 3.907   4.324   2.141   1.00 37.63  ?  18  THR   B N    1 
ATOM   287   C  CA   . THR   A 1 19  ? 4.470   3.322   1.254   1.00 37.52  ?  18  THR   B CA   1 
ATOM   288   C  C    . THR   A 1 19  ? 5.689   3.874   0.531   1.00 39.26  ?  18  THR   B C    1 
ATOM   289   O  O    . THR   A 1 19  ? 5.686   5.006   0.047   1.00 39.69  ?  18  THR   B O    1 
ATOM   290   C  CB   . THR   A 1 19  ? 3.446   2.863   0.235   1.00 34.57  ?  18  THR   B CB   1 
ATOM   291   O  OG1  . THR   A 1 19  ? 2.536   1.947   0.849   1.00 43.86  ?  18  THR   B OG1  1 
ATOM   292   C  CG2  . THR   A 1 19  ? 4.154   2.164   -0.936  1.00 46.53  ?  18  THR   B CG2  1 
ATOM   293   H  H    . THR   A 1 19  ? 3.178   4.682   1.859   1.00 45.15  ?  18  THR   B H    1 
ATOM   294   H  HA   . THR   A 1 19  ? 4.738   2.554   1.782   1.00 45.03  ?  18  THR   B HA   1 
ATOM   295   H  HB   . THR   A 1 19  ? 2.952   3.626   -0.104  1.00 41.49  ?  18  THR   B HB   1 
ATOM   296   H  HG1  . THR   A 1 19  ? 1.896   1.786   0.330   1.00 52.64  ?  18  THR   B HG1  1 
ATOM   297   H  HG21 . THR   A 1 19  ? 3.509   1.675   -1.470  1.00 55.83  ?  18  THR   B HG21 1 
ATOM   298   H  HG22 . THR   A 1 19  ? 4.593   2.822   -1.498  1.00 55.83  ?  18  THR   B HG22 1 
ATOM   299   H  HG23 . THR   A 1 19  ? 4.820   1.544   -0.600  1.00 55.83  ?  18  THR   B HG23 1 
ATOM   300   N  N    . GLN   A 1 20  ? 6.712   3.051   0.439   1.00 39.91  ?  19  GLN   B N    1 
ATOM   301   C  CA   . GLN   A 1 20  ? 7.989   3.404   -0.154  1.00 49.22  ?  19  GLN   B CA   1 
ATOM   302   C  C    . GLN   A 1 20  ? 8.418   2.260   -1.051  1.00 50.35  ?  19  GLN   B C    1 
ATOM   303   O  O    . GLN   A 1 20  ? 8.202   1.090   -0.714  1.00 47.31  ?  19  GLN   B O    1 
ATOM   304   C  CB   . GLN   A 1 20  ? 9.063   3.623   0.899   1.00 43.65  ?  19  GLN   B CB   1 
ATOM   305   C  CG   . GLN   A 1 20  ? 8.717   4.654   1.893   1.00 44.15  ?  19  GLN   B CG   1 
ATOM   306   C  CD   . GLN   A 1 20  ? 8.624   6.007   1.262   1.00 49.08  ?  19  GLN   B CD   1 
ATOM   307   O  OE1  . GLN   A 1 20  ? 9.010   6.195   0.109   1.00 53.34  ?  19  GLN   B OE1  1 
ATOM   308   N  NE2  . GLN   A 1 20  ? 8.096   6.969   2.011   1.00 49.68  ?  19  GLN   B NE2  1 
ATOM   309   H  H    . GLN   A 1 20  ? 6.693   2.241   0.727   1.00 47.89  ?  19  GLN   B H    1 
ATOM   310   H  HA   . GLN   A 1 20  ? 7.896   4.222   -0.668  1.00 59.07  ?  19  GLN   B HA   1 
ATOM   311   H  HB2  . GLN   A 1 20  ? 9.208   2.789   1.374   1.00 52.37  ?  19  GLN   B HB2  1 
ATOM   312   H  HB3  . GLN   A 1 20  ? 9.881   3.899   0.457   1.00 52.37  ?  19  GLN   B HB3  1 
ATOM   313   H  HG2  . GLN   A 1 20  ? 7.859   4.442   2.291   1.00 52.97  ?  19  GLN   B HG2  1 
ATOM   314   H  HG3  . GLN   A 1 20  ? 9.403   4.683   2.579   1.00 52.97  ?  19  GLN   B HG3  1 
ATOM   315   H  HE21 . GLN   A 1 20  ? 7.832   6.795   2.811   1.00 59.61  ?  19  GLN   B HE21 1 
ATOM   316   H  HE22 . GLN   A 1 20  ? 8.020   7.766   1.696   1.00 59.61  ?  19  GLN   B HE22 1 
ATOM   317   N  N    . VAL   A 1 21  ? 8.978   2.600   -2.206  1.00 53.71  ?  20  VAL   B N    1 
ATOM   318   C  CA   . VAL   A 1 21  ? 9.661   1.648   -3.064  1.00 52.87  ?  20  VAL   B CA   1 
ATOM   319   C  C    . VAL   A 1 21  ? 11.135  1.901   -2.837  1.00 53.57  ?  20  VAL   B C    1 
ATOM   320   O  O    . VAL   A 1 21  ? 11.575  3.052   -2.875  1.00 53.39  ?  20  VAL   B O    1 
ATOM   321   C  CB   . VAL   A 1 21  ? 9.256   1.810   -4.540  1.00 60.93  ?  20  VAL   B CB   1 
ATOM   322   C  CG1  . VAL   A 1 21  ? 9.372   3.247   -4.985  1.00 65.10  ?  20  VAL   B CG1  1 
ATOM   323   C  CG2  . VAL   A 1 21  ? 10.094  0.864   -5.407  1.00 62.03  ?  20  VAL   B CG2  1 
ATOM   324   H  H    . VAL   A 1 21  ? 8.973   3.401   -2.521  1.00 64.45  ?  20  VAL   B H    1 
ATOM   325   H  HA   . VAL   A 1 21  ? 9.442   0.732   -2.829  1.00 63.45  ?  20  VAL   B HA   1 
ATOM   326   H  HB   . VAL   A 1 21  ? 8.323   1.570   -4.650  1.00 73.12  ?  20  VAL   B HB   1 
ATOM   327   H  HG11 . VAL   A 1 21  ? 9.136   3.307   -5.924  1.00 78.13  ?  20  VAL   B HG11 1 
ATOM   328   H  HG12 . VAL   A 1 21  ? 8.768   3.791   -4.457  1.00 78.13  ?  20  VAL   B HG12 1 
ATOM   329   H  HG13 . VAL   A 1 21  ? 10.286  3.545   -4.854  1.00 78.13  ?  20  VAL   B HG13 1 
ATOM   330   H  HG21 . VAL   A 1 21  ? 9.833   0.971   -6.335  1.00 74.44  ?  20  VAL   B HG21 1 
ATOM   331   H  HG22 . VAL   A 1 21  ? 11.033  1.085   -5.300  1.00 74.44  ?  20  VAL   B HG22 1 
ATOM   332   H  HG23 . VAL   A 1 21  ? 9.935   -0.050  -5.122  1.00 74.44  ?  20  VAL   B HG23 1 
ATOM   333   N  N    . VAL   A 1 22  ? 11.872  0.850   -2.500  1.00 55.56  ?  21  VAL   B N    1 
ATOM   334   C  CA   . VAL   A 1 22  ? 13.270  0.946   -2.122  1.00 51.94  ?  21  VAL   B CA   1 
ATOM   335   C  C    . VAL   A 1 22  ? 14.095  0.182   -3.139  1.00 53.51  ?  21  VAL   B C    1 
ATOM   336   O  O    . VAL   A 1 22  ? 13.691  -0.892  -3.603  1.00 46.42  ?  21  VAL   B O    1 
ATOM   337   C  CB   . VAL   A 1 22  ? 13.504  0.400   -0.701  1.00 50.66  ?  21  VAL   B CB   1 
ATOM   338   C  CG1  . VAL   A 1 22  ? 12.889  -0.951  -0.508  1.00 50.06  ?  21  VAL   B CG1  1 
ATOM   339   C  CG2  . VAL   A 1 22  ? 14.985  0.262   -0.411  1.00 64.98  ?  21  VAL   B CG2  1 
ATOM   340   H  H    . VAL   A 1 22  ? 11.571  0.044   -2.482  1.00 66.68  ?  21  VAL   B H    1 
ATOM   341   H  HA   . VAL   A 1 22  ? 13.549  1.875   -2.141  1.00 62.33  ?  21  VAL   B HA   1 
ATOM   342   H  HB   . VAL   A 1 22  ? 13.092  1.034   -0.094  1.00 60.80  ?  21  VAL   B HB   1 
ATOM   343   H  HG11 . VAL   A 1 22  ? 13.077  -1.258  0.393   1.00 60.07  ?  21  VAL   B HG11 1 
ATOM   344   H  HG12 . VAL   A 1 22  ? 11.930  -0.883  -0.640  1.00 60.07  ?  21  VAL   B HG12 1 
ATOM   345   H  HG13 . VAL   A 1 22  ? 13.269  -1.566  -1.153  1.00 60.07  ?  21  VAL   B HG13 1 
ATOM   346   H  HG21 . VAL   A 1 22  ? 15.100  -0.092  0.485   1.00 77.97  ?  21  VAL   B HG21 1 
ATOM   347   H  HG22 . VAL   A 1 22  ? 15.379  -0.343  -1.059  1.00 77.97  ?  21  VAL   B HG22 1 
ATOM   348   H  HG23 . VAL   A 1 22  ? 15.402  1.135   -0.478  1.00 77.97  ?  21  VAL   B HG23 1 
ATOM   349   N  N    . ASP   A 1 23  ? 15.252  0.753   -3.467  1.00 57.47  ?  22  ASP   B N    1 
ATOM   350   C  CA   . ASP   A 1 23  ? 16.227  0.158   -4.367  1.00 60.10  ?  22  ASP   B CA   1 
ATOM   351   C  C    . ASP   A 1 23  ? 17.111  -0.805  -3.587  1.00 52.51  ?  22  ASP   B C    1 
ATOM   352   O  O    . ASP   A 1 23  ? 17.822  -0.386  -2.670  1.00 53.52  ?  22  ASP   B O    1 
ATOM   353   C  CB   . ASP   A 1 23  ? 17.050  1.283   -4.993  1.00 68.67  ?  22  ASP   B CB   1 
ATOM   354   C  CG   . ASP   A 1 23  ? 17.852  0.836   -6.206  1.00 71.11  ?  22  ASP   B CG   1 
ATOM   355   O  OD1  . ASP   A 1 23  ? 17.867  1.599   -7.208  1.00 65.00  ?  22  ASP   B OD1  1 
ATOM   356   O  OD2  . ASP   A 1 23  ? 18.478  -0.256  -6.138  1.00 70.20  -1 22  ASP   B OD2  1 
ATOM   357   H  H    . ASP   A 1 23  ? 15.503  1.518   -3.167  1.00 68.96  ?  22  ASP   B H    1 
ATOM   358   H  HA   . ASP   A 1 23  ? 15.792  -0.348  -5.071  1.00 72.12  ?  22  ASP   B HA   1 
ATOM   359   H  HB2  . ASP   A 1 23  ? 16.450  1.991   -5.276  1.00 82.40  ?  22  ASP   B HB2  1 
ATOM   360   H  HB3  . ASP   A 1 23  ? 17.673  1.622   -4.331  1.00 82.40  ?  22  ASP   B HB3  1 
ATOM   361   N  N    . MET   A 1 24  ? 17.064  -2.094  -3.936  1.00 48.19  ?  23  MET   B N    1 
ATOM   362   C  CA   . MET   A 1 24  ? 17.860  -3.067  -3.187  1.00 50.98  ?  23  MET   B CA   1 
ATOM   363   C  C    . MET   A 1 24  ? 19.358  -2.916  -3.429  1.00 60.95  ?  23  MET   B C    1 
ATOM   364   O  O    . MET   A 1 24  ? 20.131  -3.713  -2.882  1.00 60.45  ?  23  MET   B O    1 
ATOM   365   C  CB   . MET   A 1 24  ? 17.428  -4.497  -3.537  1.00 48.44  ?  23  MET   B CB   1 
ATOM   366   C  CG   . MET   A 1 24  ? 15.932  -4.725  -3.441  1.00 57.45  ?  23  MET   B CG   1 
ATOM   367   S  SD   . MET   A 1 24  ? 15.319  -6.427  -3.515  1.00 57.46  ?  23  MET   B SD   1 
ATOM   368   C  CE   . MET   A 1 24  ? 16.049  -7.104  -2.028  1.00 58.74  ?  23  MET   B CE   1 
ATOM   369   H  H    . MET   A 1 24  ? 16.595  -2.418  -4.580  1.00 57.83  ?  23  MET   B H    1 
ATOM   370   H  HA   . MET   A 1 24  ? 17.682  -2.933  -2.243  1.00 61.17  ?  23  MET   B HA   1 
ATOM   371   H  HB2  . MET   A 1 24  ? 17.699  -4.690  -4.448  1.00 58.12  ?  23  MET   B HB2  1 
ATOM   372   H  HB3  . MET   A 1 24  ? 17.862  -5.112  -2.925  1.00 58.12  ?  23  MET   B HB3  1 
ATOM   373   H  HG2  . MET   A 1 24  ? 15.632  -4.360  -2.594  1.00 68.94  ?  23  MET   B HG2  1 
ATOM   374   H  HG3  . MET   A 1 24  ? 15.514  -4.249  -4.174  1.00 68.94  ?  23  MET   B HG3  1 
ATOM   375   H  HE1  . MET   A 1 24  ? 15.791  -8.035  -1.946  1.00 70.49  ?  23  MET   B HE1  1 
ATOM   376   H  HE2  . MET   A 1 24  ? 17.015  -7.032  -2.090  1.00 70.49  ?  23  MET   B HE2  1 
ATOM   377   H  HE3  . MET   A 1 24  ? 15.728  -6.602  -1.263  1.00 70.49  ?  23  MET   B HE3  1 
ATOM   378   N  N    . SER   A 1 25  ? 19.762  -1.933  -4.247  1.00 63.21  ?  24  SER   B N    1 
ATOM   379   C  CA   . SER   A 1 25  ? 21.145  -1.657  -4.600  1.00 61.49  ?  24  SER   B CA   1 
ATOM   380   C  C    . SER   A 1 25  ? 21.702  -0.471  -3.832  1.00 65.97  ?  24  SER   B C    1 
ATOM   381   O  O    . SER   A 1 25  ? 22.755  0.053   -4.191  1.00 68.81  ?  24  SER   B O    1 
ATOM   382   C  CB   . SER   A 1 25  ? 21.248  -1.392  -6.105  1.00 64.91  ?  24  SER   B CB   1 
ATOM   383   O  OG   . SER   A 1 25  ? 22.094  -0.288  -6.386  1.00 69.73  ?  24  SER   B OG   1 
ATOM   384   H  H    . SER   A 1 25  ? 19.216  -1.388  -4.626  1.00 75.86  ?  24  SER   B H    1 
ATOM   385   H  HA   . SER   A 1 25  ? 21.687  -2.434  -4.392  1.00 73.79  ?  24  SER   B HA   1 
ATOM   386   H  HB2  . SER   A 1 25  ? 21.610  -2.182  -6.537  1.00 77.89  ?  24  SER   B HB2  1 
ATOM   387   H  HB3  . SER   A 1 25  ? 20.361  -1.203  -6.450  1.00 77.89  ?  24  SER   B HB3  1 
ATOM   388   H  HG   . SER   A 1 25  ? 22.161  -0.182  -7.216  1.00 83.68  ?  24  SER   B HG   1 
ATOM   389   N  N    . MET   A 1 26  ? 20.998  -0.007  -2.809  1.00 65.08  ?  25  MET   B N    1 
ATOM   390   C  CA   . MET   A 1 26  ? 21.462  1.090   -1.977  1.00 59.46  ?  25  MET   B CA   1 
ATOM   391   C  C    . MET   A 1 26  ? 21.050  0.762   -0.557  1.00 58.85  ?  25  MET   B C    1 
ATOM   392   O  O    . MET   A 1 26  ? 20.045  0.081   -0.348  1.00 63.98  ?  25  MET   B O    1 
ATOM   393   C  CB   . MET   A 1 26  ? 20.869  2.444   -2.378  1.00 62.01  ?  25  MET   B CB   1 
ATOM   394   C  CG   . MET   A 1 26  ? 20.563  2.638   -3.856  1.00 64.35  ?  25  MET   B CG   1 
ATOM   395   S  SD   . MET   A 1 26  ? 20.165  4.382   -4.188  1.00 65.80  ?  25  MET   B SD   1 
ATOM   396   C  CE   . MET   A 1 26  ? 19.070  4.266   -5.591  1.00 51.03  ?  25  MET   B CE   1 
ATOM   397   H  H    . MET   A 1 26  ? 20.233  -0.319  -2.572  1.00 78.09  ?  25  MET   B H    1 
ATOM   398   H  HA   . MET   A 1 26  ? 22.424  1.177   -2.059  1.00 71.35  ?  25  MET   B HA   1 
ATOM   399   H  HB2  . MET   A 1 26  ? 20.036  2.563   -1.896  1.00 74.41  ?  25  MET   B HB2  1 
ATOM   400   H  HB3  . MET   A 1 26  ? 21.500  3.136   -2.124  1.00 74.41  ?  25  MET   B HB3  1 
ATOM   401   H  HG2  . MET   A 1 26  ? 21.337  2.389   -4.385  1.00 77.22  ?  25  MET   B HG2  1 
ATOM   402   H  HG3  . MET   A 1 26  ? 19.801  2.092   -4.106  1.00 77.22  ?  25  MET   B HG3  1 
ATOM   403   H  HE1  . MET   A 1 26  ? 18.831  5.161   -5.880  1.00 61.23  ?  25  MET   B HE1  1 
ATOM   404   H  HE2  . MET   A 1 26  ? 19.525  3.798   -6.309  1.00 61.23  ?  25  MET   B HE2  1 
ATOM   405   H  HE3  . MET   A 1 26  ? 18.274  3.778   -5.331  1.00 61.23  ?  25  MET   B HE3  1 
ATOM   406   N  N    . THR   A 1 27  ? 21.807  1.243   0.423   1.00 54.77  ?  26  THR   B N    1 
ATOM   407   C  CA   . THR   A 1 27  ? 21.363  1.028   1.794   1.00 57.89  ?  26  THR   B CA   1 
ATOM   408   C  C    . THR   A 1 27  ? 20.080  1.831   2.076   1.00 57.94  ?  26  THR   B C    1 
ATOM   409   O  O    . THR   A 1 27  ? 19.615  2.648   1.266   1.00 52.51  ?  26  THR   B O    1 
ATOM   410   C  CB   . THR   A 1 27  ? 22.454  1.408   2.785   1.00 57.67  ?  26  THR   B CB   1 
ATOM   411   O  OG1  . THR   A 1 27  ? 22.495  2.829   2.903   1.00 58.12  ?  26  THR   B OG1  1 
ATOM   412   C  CG2  . THR   A 1 27  ? 23.796  0.886   2.336   1.00 59.58  ?  26  THR   B CG2  1 
ATOM   413   H  H    . THR   A 1 27  ? 22.544  1.676   0.325   1.00 65.72  ?  26  THR   B H    1 
ATOM   414   H  HA   . THR   A 1 27  ? 21.167  0.085   1.915   1.00 69.46  ?  26  THR   B HA   1 
ATOM   415   H  HB   . THR   A 1 27  ? 22.267  1.016   3.652   1.00 69.20  ?  26  THR   B HB   1 
ATOM   416   H  HG1  . THR   A 1 27  ? 23.208  3.066   3.277   1.00 69.75  ?  26  THR   B HG1  1 
ATOM   417   H  HG21 . THR   A 1 27  ? 24.476  1.116   2.987   1.00 71.50  ?  26  THR   B HG21 1 
ATOM   418   H  HG22 . THR   A 1 27  ? 23.762  -0.079  2.242   1.00 71.50  ?  26  THR   B HG22 1 
ATOM   419   H  HG23 . THR   A 1 27  ? 24.034  1.277   1.480   1.00 71.50  ?  26  THR   B HG23 1 
ATOM   420   N  N    . TYR   A 1 28  ? 19.510  1.600   3.260   1.00 57.97  ?  27  TYR   B N    1 
ATOM   421   C  CA   . TYR   A 1 28  ? 18.362  2.401   3.685   1.00 53.39  ?  27  TYR   B CA   1 
ATOM   422   C  C    . TYR   A 1 28  ? 18.763  3.840   3.962   1.00 54.81  ?  27  TYR   B C    1 
ATOM   423   O  O    . TYR   A 1 28  ? 18.053  4.780   3.578   1.00 53.38  ?  27  TYR   B O    1 
ATOM   424   C  CB   . TYR   A 1 28  ? 17.750  1.800   4.930   1.00 40.75  ?  27  TYR   B CB   1 
ATOM   425   C  CG   . TYR   A 1 28  ? 17.020  0.534   4.664   1.00 40.46  ?  27  TYR   B CG   1 
ATOM   426   C  CD1  . TYR   A 1 28  ? 15.727  0.555   4.155   1.00 44.68  ?  27  TYR   B CD1  1 
ATOM   427   C  CD2  . TYR   A 1 28  ? 17.590  -0.677  4.942   1.00 37.62  ?  27  TYR   B CD2  1 
ATOM   428   C  CE1  . TYR   A 1 28  ? 15.039  -0.618  3.899   1.00 32.33  ?  27  TYR   B CE1  1 
ATOM   429   C  CE2  . TYR   A 1 28  ? 16.906  -1.847  4.731   1.00 46.06  ?  27  TYR   B CE2  1 
ATOM   430   C  CZ   . TYR   A 1 28  ? 15.635  -1.817  4.201   1.00 39.60  ?  27  TYR   B CZ   1 
ATOM   431   O  OH   . TYR   A 1 28  ? 14.983  -2.996  3.949   1.00 35.81  ?  27  TYR   B OH   1 
ATOM   432   H  H    . TYR   A 1 28  ? 19.762  1.001   3.822   1.00 69.56  ?  27  TYR   B H    1 
ATOM   433   H  HA   . TYR   A 1 28  ? 17.703  2.394   2.973   1.00 64.07  ?  27  TYR   B HA   1 
ATOM   434   H  HB2  . TYR   A 1 28  ? 18.456  1.610   5.568   1.00 48.90  ?  27  TYR   B HB2  1 
ATOM   435   H  HB3  . TYR   A 1 28  ? 17.122  2.434   5.310   1.00 48.90  ?  27  TYR   B HB3  1 
ATOM   436   H  HD1  . TYR   A 1 28  ? 15.318  1.372   3.983   1.00 53.62  ?  27  TYR   B HD1  1 
ATOM   437   H  HD2  . TYR   A 1 28  ? 18.456  -0.708  5.279   1.00 45.15  ?  27  TYR   B HD2  1 
ATOM   438   H  HE1  . TYR   A 1 28  ? 14.186  -0.594  3.528   1.00 38.80  ?  27  TYR   B HE1  1 
ATOM   439   H  HE2  . TYR   A 1 28  ? 17.301  -2.661  4.946   1.00 55.28  ?  27  TYR   B HE2  1 
ATOM   440   H  HH   . TYR   A 1 28  ? 15.529  -3.575  3.680   1.00 42.98  ?  27  TYR   B HH   1 
ATOM   441   N  N    . GLY   A 1 29  ? 19.892  4.030   4.642   1.00 47.66  ?  28  GLY   B N    1 
ATOM   442   C  CA   . GLY   A 1 29  ? 20.381  5.374   4.891   1.00 51.80  ?  28  GLY   B CA   1 
ATOM   443   C  C    . GLY   A 1 29  ? 20.602  6.200   3.633   1.00 51.90  ?  28  GLY   B C    1 
ATOM   444   O  O    . GLY   A 1 29  ? 20.492  7.428   3.661   1.00 52.51  ?  28  GLY   B O    1 
ATOM   445   H  H    . GLY   A 1 29  ? 20.386  3.403   4.964   1.00 57.19  ?  28  GLY   B H    1 
ATOM   446   H  HA2  . GLY   A 1 29  ? 19.740  5.844   5.447   1.00 62.17  ?  28  GLY   B HA2  1 
ATOM   447   H  HA3  . GLY   A 1 29  ? 21.227  5.318   5.363   1.00 62.17  ?  28  GLY   B HA3  1 
ATOM   448   N  N    . GLN   A 1 30  ? 20.943  5.558   2.515   1.00 54.18  ?  29  GLN   B N    1 
ATOM   449   C  CA   . GLN   A 1 30  ? 21.154  6.339   1.302   1.00 50.50  ?  29  GLN   B CA   1 
ATOM   450   C  C    . GLN   A 1 30  ? 19.845  6.816   0.721   1.00 59.71  ?  29  GLN   B C    1 
ATOM   451   O  O    . GLN   A 1 30  ? 19.853  7.712   -0.121  1.00 60.57  ?  29  GLN   B O    1 
ATOM   452   C  CB   . GLN   A 1 30  ? 21.918  5.529   0.259   1.00 52.88  ?  29  GLN   B CB   1 
ATOM   453   C  CG   . GLN   A 1 30  ? 23.089  4.777   0.880   1.00 66.58  ?  29  GLN   B CG   1 
ATOM   454   C  CD   . GLN   A 1 30  ? 24.067  4.210   -0.159  1.00 64.88  ?  29  GLN   B CD   1 
ATOM   455   O  OE1  . GLN   A 1 30  ? 24.706  3.182   0.079   1.00 58.33  ?  29  GLN   B OE1  1 
ATOM   456   N  NE2  . GLN   A 1 30  ? 24.196  4.891   -1.303  1.00 64.28  ?  29  GLN   B NE2  1 
ATOM   457   H  H    . GLN   A 1 30  ? 21.052  4.709   2.438   1.00 65.01  ?  29  GLN   B H    1 
ATOM   458   H  HA   . GLN   A 1 30  ? 21.701  7.110   1.519   1.00 60.60  ?  29  GLN   B HA   1 
ATOM   459   H  HB2  . GLN   A 1 30  ? 21.319  4.882   -0.144  1.00 63.45  ?  29  GLN   B HB2  1 
ATOM   460   H  HB3  . GLN   A 1 30  ? 22.265  6.128   -0.420  1.00 63.45  ?  29  GLN   B HB3  1 
ATOM   461   H  HG2  . GLN   A 1 30  ? 23.582  5.383   1.454   1.00 79.89  ?  29  GLN   B HG2  1 
ATOM   462   H  HG3  . GLN   A 1 30  ? 22.744  4.034   1.401   1.00 79.89  ?  29  GLN   B HG3  1 
ATOM   463   H  HE21 . GLN   A 1 30  ? 23.742  5.610   -1.429  1.00 77.13  ?  29  GLN   B HE21 1 
ATOM   464   H  HE22 . GLN   A 1 30  ? 24.733  4.609   -1.912  1.00 77.13  ?  29  GLN   B HE22 1 
ATOM   465   N  N    . GLN   A 1 31  ? 18.725  6.215   1.129   1.00 64.86  ?  30  GLN   B N    1 
ATOM   466   C  CA   . GLN   A 1 31  ? 17.400  6.534   0.611   1.00 54.02  ?  30  GLN   B CA   1 
ATOM   467   C  C    . GLN   A 1 31  ? 16.540  7.277   1.610   1.00 51.36  ?  30  GLN   B C    1 
ATOM   468   O  O    . GLN   A 1 31  ? 15.790  8.184   1.232   1.00 50.41  ?  30  GLN   B O    1 
ATOM   469   C  CB   . GLN   A 1 31  ? 16.687  5.245   0.200   1.00 59.96  ?  30  GLN   B CB   1 
ATOM   470   C  CG   . GLN   A 1 31  ? 17.299  4.619   -1.052  1.00 70.66  ?  30  GLN   B CG   1 
ATOM   471   C  CD   . GLN   A 1 31  ? 17.054  3.127   -1.167  1.00 62.11  ?  30  GLN   B CD   1 
ATOM   472   O  OE1  . GLN   A 1 31  ? 16.164  2.693   -1.890  1.00 60.20  ?  30  GLN   B OE1  1 
ATOM   473   N  NE2  . GLN   A 1 31  ? 17.875  2.334   -0.494  1.00 59.97  ?  30  GLN   B NE2  1 
ATOM   474   H  H    . GLN   A 1 31  ? 18.711  5.597   1.727   1.00 77.84  ?  30  GLN   B H    1 
ATOM   475   H  HA   . GLN   A 1 31  ? 17.490  7.092   -0.177  1.00 64.82  ?  30  GLN   B HA   1 
ATOM   476   H  HB2  . GLN   A 1 31  ? 16.753  4.601   0.923   1.00 71.96  ?  30  GLN   B HB2  1 
ATOM   477   H  HB3  . GLN   A 1 31  ? 15.756  5.442   0.015   1.00 71.96  ?  30  GLN   B HB3  1 
ATOM   478   H  HG2  . GLN   A 1 31  ? 16.914  5.044   -1.834  1.00 84.79  ?  30  GLN   B HG2  1 
ATOM   479   H  HG3  . GLN   A 1 31  ? 18.259  4.761   -1.036  1.00 84.79  ?  30  GLN   B HG3  1 
ATOM   480   H  HE21 . GLN   A 1 31  ? 18.509  2.673   -0.022  1.00 71.96  ?  30  GLN   B HE21 1 
ATOM   481   H  HE22 . GLN   A 1 31  ? 17.774  1.481   -0.529  1.00 71.96  ?  30  GLN   B HE22 1 
ATOM   482   N  N    . PHE   A 1 32  ? 16.651  6.914   2.887   1.00 58.02  ?  31  PHE   B N    1 
ATOM   483   C  CA   . PHE   A 1 32  ? 15.799  7.469   3.927   1.00 55.64  ?  31  PHE   B CA   1 
ATOM   484   C  C    . PHE   A 1 32  ? 16.536  8.270   4.967   1.00 50.50  ?  31  PHE   B C    1 
ATOM   485   O  O    . PHE   A 1 32  ? 15.887  9.011   5.701   1.00 53.97  ?  31  PHE   B O    1 
ATOM   486   C  CB   . PHE   A 1 32  ? 15.057  6.345   4.656   1.00 48.56  ?  31  PHE   B CB   1 
ATOM   487   C  CG   . PHE   A 1 32  ? 14.226  5.515   3.751   1.00 47.12  ?  31  PHE   B CG   1 
ATOM   488   C  CD1  . PHE   A 1 32  ? 13.465  6.107   2.763   1.00 49.06  ?  31  PHE   B CD1  1 
ATOM   489   C  CD2  . PHE   A 1 32  ? 14.182  4.144   3.889   1.00 52.34  ?  31  PHE   B CD2  1 
ATOM   490   C  CE1  . PHE   A 1 32  ? 12.687  5.342   1.921   1.00 51.44  ?  31  PHE   B CE1  1 
ATOM   491   C  CE2  . PHE   A 1 32  ? 13.395  3.371   3.039   1.00 61.08  ?  31  PHE   B CE2  1 
ATOM   492   C  CZ   . PHE   A 1 32  ? 12.651  3.971   2.056   1.00 48.17  ?  31  PHE   B CZ   1 
ATOM   493   H  H    . PHE   A 1 32  ? 17.223  6.340   3.177   1.00 69.62  ?  31  PHE   B H    1 
ATOM   494   H  HA   . PHE   A 1 32  ? 15.148  8.050   3.504   1.00 66.76  ?  31  PHE   B HA   1 
ATOM   495   H  HB2  . PHE   A 1 32  ? 15.707  5.765   5.082   1.00 58.28  ?  31  PHE   B HB2  1 
ATOM   496   H  HB3  . PHE   A 1 32  ? 14.473  6.736   5.324   1.00 58.28  ?  31  PHE   B HB3  1 
ATOM   497   H  HD1  . PHE   A 1 32  ? 13.478  7.031   2.665   1.00 58.87  ?  31  PHE   B HD1  1 
ATOM   498   H  HD2  . PHE   A 1 32  ? 14.683  3.732   4.555   1.00 62.80  ?  31  PHE   B HD2  1 
ATOM   499   H  HE1  . PHE   A 1 32  ? 12.183  5.754   1.257   1.00 61.73  ?  31  PHE   B HE1  1 
ATOM   500   H  HE2  . PHE   A 1 32  ? 13.375  2.447   3.138   1.00 73.30  ?  31  PHE   B HE2  1 
ATOM   501   H  HZ   . PHE   A 1 32  ? 12.126  3.457   1.486   1.00 57.80  ?  31  PHE   B HZ   1 
ATOM   502   N  N    . GLY   A 1 33  ? 17.853  8.168   5.030   1.00 41.50  ?  32  GLY   B N    1 
ATOM   503   C  CA   . GLY   A 1 33  ? 18.603  8.647   6.166   1.00 51.04  ?  32  GLY   B CA   1 
ATOM   504   C  C    . GLY   A 1 33  ? 18.594  7.605   7.265   1.00 44.52  ?  32  GLY   B C    1 
ATOM   505   O  O    . GLY   A 1 33  ? 18.334  6.423   7.021   1.00 50.84  ?  32  GLY   B O    1 
ATOM   506   H  H    . GLY   A 1 33  ? 18.340  7.818   4.414   1.00 49.79  ?  32  GLY   B H    1 
ATOM   507   H  HA2  . GLY   A 1 33  ? 19.521  8.824   5.905   1.00 61.25  ?  32  GLY   B HA2  1 
ATOM   508   H  HA3  . GLY   A 1 33  ? 18.207  9.466   6.503   1.00 61.25  ?  32  GLY   B HA3  1 
ATOM   509   N  N    . PRO   A 1 34  ? 18.836  8.020   8.502   1.00 44.92  ?  33  PRO   B N    1 
ATOM   510   C  CA   . PRO   A 1 34  ? 18.731  7.072   9.623   1.00 44.38  ?  33  PRO   B CA   1 
ATOM   511   C  C    . PRO   A 1 34  ? 17.394  6.338   9.597   1.00 52.68  ?  33  PRO   B C    1 
ATOM   512   O  O    . PRO   A 1 34  ? 16.335  6.945   9.418   1.00 45.38  ?  33  PRO   B O    1 
ATOM   513   C  CB   . PRO   A 1 34  ? 18.871  7.961   10.857  1.00 49.96  ?  33  PRO   B CB   1 
ATOM   514   C  CG   . PRO   A 1 34  ? 19.624  9.178   10.366  1.00 47.85  ?  33  PRO   B CG   1 
ATOM   515   C  CD   . PRO   A 1 34  ? 19.201  9.384   8.929   1.00 47.29  ?  33  PRO   B CD   1 
ATOM   516   H  HA   . PRO   A 1 34  ? 19.458  6.431   9.604   1.00 53.25  ?  33  PRO   B HA   1 
ATOM   517   H  HB2  . PRO   A 1 34  ? 17.994  8.206   11.192  1.00 59.95  ?  33  PRO   B HB2  1 
ATOM   518   H  HB3  . PRO   A 1 34  ? 19.372  7.497   11.546  1.00 59.95  ?  33  PRO   B HB3  1 
ATOM   519   H  HG2  . PRO   A 1 34  ? 19.386  9.948   10.906  1.00 57.42  ?  33  PRO   B HG2  1 
ATOM   520   H  HG3  . PRO   A 1 34  ? 20.578  9.015   10.422  1.00 57.42  ?  33  PRO   B HG3  1 
ATOM   521   H  HD2  . PRO   A 1 34  ? 18.439  9.982   8.872   1.00 56.75  ?  33  PRO   B HD2  1 
ATOM   522   H  HD3  . PRO   A 1 34  ? 19.934  9.731   8.397   1.00 56.75  ?  33  PRO   B HD3  1 
ATOM   523   N  N    . THR   A 1 35  ? 17.456  5.017   9.768   1.00 50.80  ?  34  THR   B N    1 
ATOM   524   C  CA   . THR   A 1 35  ? 16.341  4.127   9.500   1.00 42.56  ?  34  THR   B CA   1 
ATOM   525   C  C    . THR   A 1 35  ? 16.438  2.942   10.438  1.00 44.40  ?  34  THR   B C    1 
ATOM   526   O  O    . THR   A 1 35  ? 17.530  2.421   10.661  1.00 48.31  ?  34  THR   B O    1 
ATOM   527   C  CB   . THR   A 1 35  ? 16.366  3.633   8.057   1.00 51.34  ?  34  THR   B CB   1 
ATOM   528   O  OG1  . THR   A 1 35  ? 16.056  4.707   7.159   1.00 55.50  ?  34  THR   B OG1  1 
ATOM   529   C  CG2  . THR   A 1 35  ? 15.375  2.494   7.863   1.00 48.48  ?  34  THR   B CG2  1 
ATOM   530   H  H    . THR   A 1 35  ? 18.157  4.605   10.047  1.00 60.97  ?  34  THR   B H    1 
ATOM   531   H  HA   . THR   A 1 35  ? 15.505  4.591   9.658   1.00 51.07  ?  34  THR   B HA   1 
ATOM   532   H  HB   . THR   A 1 35  ? 17.253  3.300   7.850   1.00 61.61  ?  34  THR   B HB   1 
ATOM   533   H  HG1  . THR   A 1 35  ? 16.660  5.290   7.189   1.00 66.60  ?  34  THR   B HG1  1 
ATOM   534   H  HG21 . THR   A 1 35  ? 15.313  2.265   6.922   1.00 58.18  ?  34  THR   B HG21 1 
ATOM   535   H  HG22 . THR   A 1 35  ? 15.667  1.712   8.358   1.00 58.18  ?  34  THR   B HG22 1 
ATOM   536   H  HG23 . THR   A 1 35  ? 14.498  2.759   8.181   1.00 58.18  ?  34  THR   B HG23 1 
ATOM   537   N  N    . TYR   A 1 36  ? 15.296  2.516   10.983  1.00 38.37  ?  35  TYR   B N    1 
ATOM   538   C  CA   . TYR   A 1 36  ? 15.272  1.459   11.984  1.00 36.40  ?  35  TYR   B CA   1 
ATOM   539   C  C    . TYR   A 1 36  ? 14.179  0.435   11.729  1.00 36.76  ?  35  TYR   B C    1 
ATOM   540   O  O    . TYR   A 1 36  ? 13.098  0.754   11.218  1.00 36.42  ?  35  TYR   B O    1 
ATOM   541   C  CB   . TYR   A 1 36  ? 15.091  2.059   13.386  1.00 41.78  ?  35  TYR   B CB   1 
ATOM   542   C  CG   . TYR   A 1 36  ? 16.045  3.214   13.708  1.00 45.73  ?  35  TYR   B CG   1 
ATOM   543   C  CD1  . TYR   A 1 36  ? 17.199  3.005   14.486  1.00 40.65  ?  35  TYR   B CD1  1 
ATOM   544   C  CD2  . TYR   A 1 36  ? 15.788  4.498   13.253  1.00 42.38  ?  35  TYR   B CD2  1 
ATOM   545   C  CE1  . TYR   A 1 36  ? 18.030  4.041   14.817  1.00 39.61  ?  35  TYR   B CE1  1 
ATOM   546   C  CE2  . TYR   A 1 36  ? 16.661  5.544   13.542  1.00 47.03  ?  35  TYR   B CE2  1 
ATOM   547   C  CZ   . TYR   A 1 36  ? 17.779  5.309   14.326  1.00 46.51  ?  35  TYR   B CZ   1 
ATOM   548   O  OH   . TYR   A 1 36  ? 18.627  6.372   14.631  1.00 54.42  ?  35  TYR   B OH   1 
ATOM   549   H  H    . TYR   A 1 36  ? 14.520  2.829   10.786  1.00 46.04  ?  35  TYR   B H    1 
ATOM   550   H  HA   . TYR   A 1 36  ? 16.108  0.971   11.923  1.00 43.68  ?  35  TYR   B HA   1 
ATOM   551   H  HB2  . TYR   A 1 36  ? 14.185  2.397   13.463  1.00 50.14  ?  35  TYR   B HB2  1 
ATOM   552   H  HB3  . TYR   A 1 36  ? 15.243  1.362   14.043  1.00 50.14  ?  35  TYR   B HB3  1 
ATOM   553   H  HD1  . TYR   A 1 36  ? 17.402  2.146   14.781  1.00 48.78  ?  35  TYR   B HD1  1 
ATOM   554   H  HD2  . TYR   A 1 36  ? 15.024  4.663   12.749  1.00 50.86  ?  35  TYR   B HD2  1 
ATOM   555   H  HE1  . TYR   A 1 36  ? 18.761  3.893   15.371  1.00 47.54  ?  35  TYR   B HE1  1 
ATOM   556   H  HE2  . TYR   A 1 36  ? 16.494  6.397   13.210  1.00 56.44  ?  35  TYR   B HE2  1 
ATOM   557   H  HH   . TYR   A 1 36  ? 18.262  7.099   14.424  1.00 65.30  ?  35  TYR   B HH   1 
ATOM   558   N  N    . LEU   A 1 37  ? 14.485  -0.806  12.088  1.00 37.46  ?  36  LEU   B N    1 
ATOM   559   C  CA   . LEU   A 1 37  ? 13.545  -1.917  12.019  1.00 45.03  ?  36  LEU   B CA   1 
ATOM   560   C  C    . LEU   A 1 37  ? 13.480  -2.576  13.389  1.00 50.12  ?  36  LEU   B C    1 
ATOM   561   O  O    . LEU   A 1 37  ? 14.439  -3.245  13.802  1.00 51.52  ?  36  LEU   B O    1 
ATOM   562   C  CB   . LEU   A 1 37  ? 13.959  -2.935  10.966  1.00 41.12  ?  36  LEU   B CB   1 
ATOM   563   C  CG   . LEU   A 1 37  ? 13.072  -4.166  10.873  1.00 46.53  ?  36  LEU   B CG   1 
ATOM   564   C  CD1  . LEU   A 1 37  ? 11.593  -3.829  10.518  1.00 47.81  ?  36  LEU   B CD1  1 
ATOM   565   C  CD2  . LEU   A 1 37  ? 13.600  -5.154  9.830   1.00 44.61  ?  36  LEU   B CD2  1 
ATOM   566   H  H    . LEU   A 1 37  ? 15.258  -1.038  12.385  1.00 44.96  ?  36  LEU   B H    1 
ATOM   567   H  HA   . LEU   A 1 37  ? 12.667  -1.572  11.791  1.00 54.04  ?  36  LEU   B HA   1 
ATOM   568   H  HB2  . LEU   A 1 37  ? 13.946  -2.500  10.098  1.00 49.34  ?  36  LEU   B HB2  1 
ATOM   569   H  HB3  . LEU   A 1 37  ? 14.857  -3.238  11.170  1.00 49.34  ?  36  LEU   B HB3  1 
ATOM   570   H  HG   . LEU   A 1 37  ? 13.087  -4.571  11.754  1.00 55.84  ?  36  LEU   B HG   1 
ATOM   571   H  HD11 . LEU   A 1 37  ? 11.095  -4.656  10.421  1.00 57.37  ?  36  LEU   B HD11 1 
ATOM   572   H  HD12 . LEU   A 1 37  ? 11.211  -3.295  11.232  1.00 57.37  ?  36  LEU   B HD12 1 
ATOM   573   H  HD13 . LEU   A 1 37  ? 11.574  -3.332  9.685   1.00 57.37  ?  36  LEU   B HD13 1 
ATOM   574   H  HD21 . LEU   A 1 37  ? 13.021  -5.932  9.810   1.00 53.53  ?  36  LEU   B HD21 1 
ATOM   575   H  HD22 . LEU   A 1 37  ? 13.605  -4.723  8.961   1.00 53.53  ?  36  LEU   B HD22 1 
ATOM   576   H  HD23 . LEU   A 1 37  ? 14.501  -5.418  10.073  1.00 53.53  ?  36  LEU   B HD23 1 
ATOM   577   N  N    . ASP   A 1 38  ? 12.344  -2.399  14.072  1.00 49.96  ?  37  ASP   B N    1 
ATOM   578   C  CA   . ASP   A 1 38  ? 12.079  -2.981  15.393  1.00 57.43  ?  37  ASP   B CA   1 
ATOM   579   C  C    . ASP   A 1 38  ? 13.197  -2.672  16.380  1.00 49.07  ?  37  ASP   B C    1 
ATOM   580   O  O    . ASP   A 1 38  ? 13.672  -3.536  17.117  1.00 46.89  ?  37  ASP   B O    1 
ATOM   581   C  CB   . ASP   A 1 38  ? 11.857  -4.490  15.298  1.00 56.62  ?  37  ASP   B CB   1 
ATOM   582   C  CG   . ASP   A 1 38  ? 10.585  -4.851  14.536  1.00 72.57  ?  37  ASP   B CG   1 
ATOM   583   O  OD1  . ASP   A 1 38  ? 10.665  -5.737  13.662  1.00 71.77  ?  37  ASP   B OD1  1 
ATOM   584   O  OD2  . ASP   A 1 38  ? 9.513   -4.255  14.794  1.00 92.59  -1 37  ASP   B OD2  1 
ATOM   585   H  H    . ASP   A 1 38  ? 11.687  -1.928  13.780  1.00 59.95  ?  37  ASP   B H    1 
ATOM   586   H  HA   . ASP   A 1 38  ? 11.267  -2.571  15.731  1.00 68.91  ?  37  ASP   B HA   1 
ATOM   587   H  HB2  . ASP   A 1 38  ? 12.609  -4.891  14.835  1.00 67.94  ?  37  ASP   B HB2  1 
ATOM   588   H  HB3  . ASP   A 1 38  ? 11.785  -4.856  16.193  1.00 67.94  ?  37  ASP   B HB3  1 
ATOM   589   N  N    . GLY   A 1 39  ? 13.600  -1.415  16.407  1.00 40.47  ?  38  GLY   B N    1 
ATOM   590   C  CA   . GLY   A 1 39  ? 14.745  -0.985  17.177  1.00 48.62  ?  38  GLY   B CA   1 
ATOM   591   C  C    . GLY   A 1 39  ? 16.080  -1.016  16.478  1.00 49.08  ?  38  GLY   B C    1 
ATOM   592   O  O    . GLY   A 1 39  ? 16.835  -0.050  16.578  1.00 48.50  ?  38  GLY   B O    1 
ATOM   593   H  H    . GLY   A 1 39  ? 13.215  -0.779  15.975  1.00 48.56  ?  38  GLY   B H    1 
ATOM   594   H  HA2  . GLY   A 1 39  ? 14.592  -0.072  17.465  1.00 58.34  ?  38  GLY   B HA2  1 
ATOM   595   H  HA3  . GLY   A 1 39  ? 14.817  -1.555  17.959  1.00 58.34  ?  38  GLY   B HA3  1 
ATOM   596   N  N    . ALA   A 1 40  ? 16.365  -2.062  15.709  1.00 49.18  ?  39  ALA   B N    1 
ATOM   597   C  CA   . ALA   A 1 40  ? 17.711  -2.236  15.170  1.00 51.51  ?  39  ALA   B CA   1 
ATOM   598   C  C    . ALA   A 1 40  ? 18.033  -1.197  14.101  1.00 53.09  ?  39  ALA   B C    1 
ATOM   599   O  O    . ALA   A 1 40  ? 17.236  -0.950  13.188  1.00 49.64  ?  39  ALA   B O    1 
ATOM   600   C  CB   . ALA   A 1 40  ? 17.867  -3.641  14.596  1.00 51.38  ?  39  ALA   B CB   1 
ATOM   601   H  H    . ALA   A 1 40  ? 15.806  -2.677  15.487  1.00 59.01  ?  39  ALA   B H    1 
ATOM   602   H  HA   . ALA   A 1 40  ? 18.347  -2.115  15.892  1.00 61.81  ?  39  ALA   B HA   1 
ATOM   603   H  HB1  . ALA   A 1 40  ? 18.702  -3.690  14.105  1.00 61.65  ?  39  ALA   B HB1  1 
ATOM   604   H  HB2  . ALA   A 1 40  ? 17.874  -4.281  15.325  1.00 61.65  ?  39  ALA   B HB2  1 
ATOM   605   H  HB3  . ALA   A 1 40  ? 17.123  -3.824  14.002  1.00 61.65  ?  39  ALA   B HB3  1 
ATOM   606   N  N    . ASP   A 1 41  ? 19.218  -0.595  14.204  1.00 51.39  ?  40  ASP   B N    1 
ATOM   607   C  CA   . ASP   A 1 41  ? 19.657  0.395   13.215  1.00 45.43  ?  40  ASP   B CA   1 
ATOM   608   C  C    . ASP   A 1 41  ? 20.027  -0.305  11.899  1.00 48.87  ?  40  ASP   B C    1 
ATOM   609   O  O    . ASP   A 1 41  ? 20.869  -1.211  11.876  1.00 47.66  ?  40  ASP   B O    1 
ATOM   610   C  CB   . ASP   A 1 41  ? 20.819  1.197   13.790  1.00 41.70  ?  40  ASP   B CB   1 
ATOM   611   C  CG   . ASP   A 1 41  ? 21.211  2.351   12.930  1.00 52.45  ?  40  ASP   B CG   1 
ATOM   612   O  OD1  . ASP   A 1 41  ? 21.951  3.219   13.419  1.00 53.71  ?  40  ASP   B OD1  1 
ATOM   613   O  OD2  . ASP   A 1 41  ? 20.799  2.387   11.767  1.00 54.84  -1 40  ASP   B OD2  1 
ATOM   614   H  H    . ASP   A 1 41  ? 19.786  -0.741  14.834  1.00 61.67  ?  40  ASP   B H    1 
ATOM   615   H  HA   . ASP   A 1 41  ? 18.939  1.015   13.012  1.00 54.51  ?  40  ASP   B HA   1 
ATOM   616   H  HB2  . ASP   A 1 41  ? 20.562  1.545   14.659  1.00 50.05  ?  40  ASP   B HB2  1 
ATOM   617   H  HB3  . ASP   A 1 41  ? 21.590  0.615   13.880  1.00 50.05  ?  40  ASP   B HB3  1 
ATOM   618   N  N    . VAL   A 1 42  ? 19.342  0.068   10.815  1.00 47.20  ?  41  VAL   B N    1 
ATOM   619   C  CA   . VAL   A 1 42  ? 19.567  -0.533  9.509   1.00 45.07  ?  41  VAL   B CA   1 
ATOM   620   C  C    . VAL   A 1 42  ? 19.992  0.515   8.484   1.00 45.83  ?  41  VAL   B C    1 
ATOM   621   O  O    . VAL   A 1 42  ? 19.922  0.273   7.264   1.00 40.70  ?  41  VAL   B O    1 
ATOM   622   C  CB   . VAL   A 1 42  ? 18.321  -1.292  9.019   1.00 47.22  ?  41  VAL   B CB   1 
ATOM   623   C  CG1  . VAL   A 1 42  ? 18.202  -2.637  9.694   1.00 46.57  ?  41  VAL   B CG1  1 
ATOM   624   C  CG2  . VAL   A 1 42  ? 17.057  -0.443  9.243   1.00 50.26  ?  41  VAL   B CG2  1 
ATOM   625   H  H    . VAL   A 1 42  ? 18.734  0.676   10.816  1.00 56.65  ?  41  VAL   B H    1 
ATOM   626   H  HA   . VAL   A 1 42  ? 20.290  -1.173  9.602   1.00 54.08  ?  41  VAL   B HA   1 
ATOM   627   H  HB   . VAL   A 1 42  ? 18.409  -1.456  8.067   1.00 56.66  ?  41  VAL   B HB   1 
ATOM   628   H  HG11 . VAL   A 1 42  ? 17.407  -3.085  9.367   1.00 55.89  ?  41  VAL   B HG11 1 
ATOM   629   H  HG12 . VAL   A 1 42  ? 18.989  -3.165  9.485   1.00 55.89  ?  41  VAL   B HG12 1 
ATOM   630   H  HG13 . VAL   A 1 42  ? 18.137  -2.505  10.653  1.00 55.89  ?  41  VAL   B HG13 1 
ATOM   631   H  HG21 . VAL   A 1 42  ? 16.287  -0.928  8.906   1.00 60.32  ?  41  VAL   B HG21 1 
ATOM   632   H  HG22 . VAL   A 1 42  ? 16.953  -0.276  10.193  1.00 60.32  ?  41  VAL   B HG22 1 
ATOM   633   H  HG23 . VAL   A 1 42  ? 17.153  0.397   8.769   1.00 60.32  ?  41  VAL   B HG23 1 
ATOM   634   N  N    . THR   A 1 43  ? 20.435  1.680   8.961   1.00 41.32  ?  42  THR   B N    1 
ATOM   635   C  CA   . THR   A 1 43  ? 20.854  2.738   8.044   1.00 50.60  ?  42  THR   B CA   1 
ATOM   636   C  C    . THR   A 1 43  ? 21.920  2.285   7.051   1.00 56.45  ?  42  THR   B C    1 
ATOM   637   O  O    . THR   A 1 43  ? 21.996  2.814   5.930   1.00 58.24  ?  42  THR   B O    1 
ATOM   638   C  CB   . THR   A 1 43  ? 21.410  3.920   8.828   1.00 48.61  ?  42  THR   B CB   1 
ATOM   639   O  OG1  . THR   A 1 43  ? 20.519  4.238   9.903   1.00 49.55  ?  42  THR   B OG1  1 
ATOM   640   C  CG2  . THR   A 1 43  ? 21.590  5.137   7.920   1.00 51.47  ?  42  THR   B CG2  1 
ATOM   641   H  H    . THR   A 1 43  ? 20.501  1.879   9.795   1.00 49.58  ?  42  THR   B H    1 
ATOM   642   H  HA   . THR   A 1 43  ? 20.067  3.007   7.546   1.00 60.72  ?  42  THR   B HA   1 
ATOM   643   H  HB   . THR   A 1 43  ? 22.280  3.691   9.191   1.00 58.33  ?  42  THR   B HB   1 
ATOM   644   H  HG1  . THR   A 1 43  ? 20.582  3.660   10.509  1.00 59.46  ?  42  THR   B HG1  1 
ATOM   645   H  HG21 . THR   A 1 43  ? 21.911  5.892   8.437   1.00 61.77  ?  42  THR   B HG21 1 
ATOM   646   H  HG22 . THR   A 1 43  ? 22.232  4.938   7.221   1.00 61.77  ?  42  THR   B HG22 1 
ATOM   647   H  HG23 . THR   A 1 43  ? 20.743  5.374   7.510   1.00 61.77  ?  42  THR   B HG23 1 
ATOM   648   N  N    . LYS   A 1 44  ? 22.782  1.358   7.451   1.00 46.92  ?  43  LYS   B N    1 
ATOM   649   C  CA   . LYS   A 1 44  ? 23.907  0.946   6.626   1.00 61.98  ?  43  LYS   B CA   1 
ATOM   650   C  C    . LYS   A 1 44  ? 23.676  -0.429  6.024   1.00 59.48  ?  43  LYS   B C    1 
ATOM   651   O  O    . LYS   A 1 44  ? 24.563  -0.943  5.341   1.00 55.93  ?  43  LYS   B O    1 
ATOM   652   C  CB   . LYS   A 1 44  ? 25.214  0.968   7.450   1.00 56.13  ?  43  LYS   B CB   1 
ATOM   653   C  CG   . LYS   A 1 44  ? 26.520  1.141   6.630   1.00 79.16  ?  43  LYS   B CG   1 
ATOM   654   C  CD   . LYS   A 1 44  ? 26.419  2.116   5.432   1.00 84.31  ?  43  LYS   B CD   1 
ATOM   655   C  CE   . LYS   A 1 44  ? 27.722  2.187   4.641   1.00 88.23  ?  43  LYS   B CE   1 
ATOM   656   N  NZ   . LYS   A 1 44  ? 27.478  2.253   3.174   1.00 73.28  ?  43  LYS   B NZ   1 
ATOM   657   H  H    . LYS   A 1 44  ? 22.735  0.949   8.206   1.00 56.31  ?  43  LYS   B H    1 
ATOM   658   H  HA   . LYS   A 1 44  ? 24.032  1.578   5.901   1.00 74.37  ?  43  LYS   B HA   1 
ATOM   659   H  HB2  . LYS   A 1 44  ? 25.167  1.707   8.076   1.00 67.35  ?  43  LYS   B HB2  1 
ATOM   660   H  HB3  . LYS   A 1 44  ? 25.285  0.129   7.931   1.00 67.35  ?  43  LYS   B HB3  1 
ATOM   661   H  HG2  . LYS   A 1 44  ? 27.211  1.479   7.221   1.00 95.00  ?  43  LYS   B HG2  1 
ATOM   662   H  HG3  . LYS   A 1 44  ? 26.779  0.275   6.278   1.00 95.00  ?  43  LYS   B HG3  1 
ATOM   663   H  HD2  . LYS   A 1 44  ? 25.718  1.815   4.834   1.00 101.17 ?  43  LYS   B HD2  1 
ATOM   664   H  HD3  . LYS   A 1 44  ? 26.216  3.005   5.761   1.00 101.17 ?  43  LYS   B HD3  1 
ATOM   665   H  HE2  . LYS   A 1 44  ? 28.212  2.981   4.904   1.00 105.88 ?  43  LYS   B HE2  1 
ATOM   666   H  HE3  . LYS   A 1 44  ? 28.251  1.395   4.825   1.00 105.88 ?  43  LYS   B HE3  1 
ATOM   667   H  HZ1  . LYS   A 1 44  ? 28.253  2.284   2.738   1.00 87.94  ?  43  LYS   B HZ1  1 
ATOM   668   H  HZ2  . LYS   A 1 44  ? 27.026  1.534   2.908   1.00 87.94  ?  43  LYS   B HZ2  1 
ATOM   669   H  HZ3  . LYS   A 1 44  ? 27.006  2.981   2.977   1.00 87.94  ?  43  LYS   B HZ3  1 
ATOM   670   N  N    . ILE   A 1 45  ? 22.509  -1.040  6.255   1.00 49.59  ?  44  ILE   B N    1 
ATOM   671   C  CA   . ILE   A 1 45  ? 22.208  -2.351  5.696   1.00 45.98  ?  44  ILE   B CA   1 
ATOM   672   C  C    . ILE   A 1 45  ? 21.562  -2.195  4.318   1.00 56.04  ?  44  ILE   B C    1 
ATOM   673   O  O    . ILE   A 1 45  ? 20.970  -1.166  3.979   1.00 57.75  ?  44  ILE   B O    1 
ATOM   674   C  CB   . ILE   A 1 45  ? 21.317  -3.141  6.673   1.00 57.22  ?  44  ILE   B CB   1 
ATOM   675   C  CG1  . ILE   A 1 45  ? 22.185  -3.847  7.727   1.00 53.44  ?  44  ILE   B CG1  1 
ATOM   676   C  CG2  . ILE   A 1 45  ? 20.455  -4.173  5.960   1.00 54.05  ?  44  ILE   B CG2  1 
ATOM   677   C  CD1  . ILE   A 1 45  ? 21.435  -4.868  8.571   1.00 93.40  ?  44  ILE   B CD1  1 
ATOM   678   H  H    . ILE   A 1 45  ? 21.877  -0.711  6.736   1.00 59.51  ?  44  ILE   B H    1 
ATOM   679   H  HA   . ILE   A 1 45  ? 23.028  -2.847  5.550   1.00 55.17  ?  44  ILE   B HA   1 
ATOM   680   H  HB   . ILE   A 1 45  ? 20.728  -2.499  7.099   1.00 68.66  ?  44  ILE   B HB   1 
ATOM   681   H  HG12 . ILE   A 1 45  ? 22.906  -4.312  7.274   1.00 64.13  ?  44  ILE   B HG12 1 
ATOM   682   H  HG13 . ILE   A 1 45  ? 22.548  -3.177  8.328   1.00 64.13  ?  44  ILE   B HG13 1 
ATOM   683   H  HG21 . ILE   A 1 45  ? 19.909  -4.635  6.615   1.00 64.87  ?  44  ILE   B HG21 1 
ATOM   684   H  HG22 . ILE   A 1 45  ? 19.888  -3.720  5.317   1.00 64.87  ?  44  ILE   B HG22 1 
ATOM   685   H  HG23 . ILE   A 1 45  ? 21.032  -4.806  5.505   1.00 64.87  ?  44  ILE   B HG23 1 
ATOM   686   H  HD11 . ILE   A 1 45  ? 22.039  -5.230  9.238   1.00 112.09 ?  44  ILE   B HD11 1 
ATOM   687   H  HD12 . ILE   A 1 45  ? 20.686  -4.430  9.006   1.00 112.09 ?  44  ILE   B HD12 1 
ATOM   688   H  HD13 . ILE   A 1 45  ? 21.114  -5.579  7.995   1.00 112.09 ?  44  ILE   B HD13 1 
ATOM   689   N  N    . LYS   A 1 46  ? 21.689  -3.171  3.539   1.00 58.56  ?  45  LYS   B N    1 
ATOM   690   C  CA   . LYS   A 1 46  ? 21.034  -3.198  2.239   1.00 57.55  ?  45  LYS   B CA   1 
ATOM   691   C  C    . LYS   A 1 46  ? 19.719  -3.970  2.318   1.00 50.67  ?  45  LYS   B C    1 
ATOM   692   O  O    . LYS   A 1 46  ? 19.589  -4.927  3.095   1.00 51.09  ?  45  LYS   B O    1 
ATOM   693   C  CB   . LYS   A 1 46  ? 21.936  -3.846  1.175   1.00 57.96  ?  45  LYS   B CB   1 
ATOM   694   C  CG   . LYS   A 1 46  ? 22.476  -2.844  0.167   1.00 63.21  ?  45  LYS   B CG   1 
ATOM   695   C  CD   . LYS   A 1 46  ? 23.528  -3.466  -0.739  1.00 63.27  ?  45  LYS   B CD   1 
ATOM   696   C  CE   . LYS   A 1 46  ? 24.307  -2.400  -1.503  1.00 68.81  ?  45  LYS   B CE   1 
ATOM   697   N  NZ   . LYS   A 1 46  ? 25.748  -2.779  -1.615  1.00 78.59  ?  45  LYS   B NZ   1 
ATOM   698   H  H    . LYS   A 1 46  ? 22.157  -3.872  3.710   1.00 70.28  ?  45  LYS   B H    1 
ATOM   699   H  HA   . LYS   A 1 46  ? 20.846  -2.289  1.957   1.00 69.06  ?  45  LYS   B HA   1 
ATOM   700   H  HB2  . LYS   A 1 46  ? 22.692  -4.265  1.616   1.00 69.56  ?  45  LYS   B HB2  1 
ATOM   701   H  HB3  . LYS   A 1 46  ? 21.424  -4.513  0.691   1.00 69.56  ?  45  LYS   B HB3  1 
ATOM   702   H  HG2  . LYS   A 1 46  ? 21.747  -2.524  -0.388  1.00 75.85  ?  45  LYS   B HG2  1 
ATOM   703   H  HG3  . LYS   A 1 46  ? 22.883  -2.101  0.640   1.00 75.85  ?  45  LYS   B HG3  1 
ATOM   704   H  HD2  . LYS   A 1 46  ? 24.154  -3.975  -0.202  1.00 75.92  ?  45  LYS   B HD2  1 
ATOM   705   H  HD3  . LYS   A 1 46  ? 23.094  -4.047  -1.383  1.00 75.92  ?  45  LYS   B HD3  1 
ATOM   706   H  HE2  . LYS   A 1 46  ? 23.941  -2.309  -2.397  1.00 82.58  ?  45  LYS   B HE2  1 
ATOM   707   H  HE3  . LYS   A 1 46  ? 24.246  -1.554  -1.033  1.00 82.58  ?  45  LYS   B HE3  1 
ATOM   708   H  HZ1  . LYS   A 1 46  ? 26.194  -2.150  -2.059  1.00 94.31  ?  45  LYS   B HZ1  1 
ATOM   709   H  HZ2  . LYS   A 1 46  ? 26.103  -2.867  -0.804  1.00 94.31  ?  45  LYS   B HZ2  1 
ATOM   710   H  HZ3  . LYS   A 1 46  ? 25.826  -3.551  -2.051  1.00 94.31  ?  45  LYS   B HZ3  1 
ATOM   711   N  N    . PRO   A 1 47  ? 18.715  -3.573  1.532   1.00 54.61  ?  46  PRO   B N    1 
ATOM   712   C  CA   . PRO   A 1 47  ? 17.437  -4.301  1.563   1.00 54.85  ?  46  PRO   B CA   1 
ATOM   713   C  C    . PRO   A 1 47  ? 17.638  -5.797  1.352   1.00 60.92  ?  46  PRO   B C    1 
ATOM   714   O  O    . PRO   A 1 47  ? 18.641  -6.244  0.782   1.00 62.63  ?  46  PRO   B O    1 
ATOM   715   C  CB   . PRO   A 1 47  ? 16.626  -3.654  0.432   1.00 48.59  ?  46  PRO   B CB   1 
ATOM   716   C  CG   . PRO   A 1 47  ? 17.092  -2.216  0.440   1.00 48.06  ?  46  PRO   B CG   1 
ATOM   717   C  CD   . PRO   A 1 47  ? 18.588  -2.284  0.811   1.00 53.27  ?  46  PRO   B CD   1 
ATOM   718   H  HA   . PRO   A 1 47  ? 16.979  -4.158  2.406   1.00 65.82  ?  46  PRO   B HA   1 
ATOM   719   H  HB2  . PRO   A 1 47  ? 16.826  -4.084  -0.414  1.00 58.30  ?  46  PRO   B HB2  1 
ATOM   720   H  HB3  . PRO   A 1 47  ? 15.676  -3.717  0.621   1.00 58.30  ?  46  PRO   B HB3  1 
ATOM   721   H  HG2  . PRO   A 1 47  ? 16.970  -1.823  -0.438  1.00 57.67  ?  46  PRO   B HG2  1 
ATOM   722   H  HG3  . PRO   A 1 47  ? 16.594  -1.710  1.101   1.00 57.67  ?  46  PRO   B HG3  1 
ATOM   723   H  HD2  . PRO   A 1 47  ? 19.139  -2.282  0.013   1.00 63.93  ?  46  PRO   B HD2  1 
ATOM   724   H  HD3  . PRO   A 1 47  ? 18.833  -1.543  1.386   1.00 63.93  ?  46  PRO   B HD3  1 
ATOM   725   N  N    . HIS   A 1 48  ? 16.679  -6.561  1.864   1.00 54.05  ?  47  HIS   B N    1 
ATOM   726   C  CA   . HIS   A 1 48  ? 16.663  -8.010  1.840   1.00 51.55  ?  47  HIS   B CA   1 
ATOM   727   C  C    . HIS   A 1 48  ? 15.273  -8.409  1.361   1.00 52.71  ?  47  HIS   B C    1 
ATOM   728   O  O    . HIS   A 1 48  ? 14.299  -7.665  1.500   1.00 41.65  ?  47  HIS   B O    1 
ATOM   729   C  CB   . HIS   A 1 48  ? 16.979  -8.589  3.219   1.00 49.06  ?  47  HIS   B CB   1 
ATOM   730   C  CG   . HIS   A 1 48  ? 17.227  -10.065 3.223   1.00 54.05  ?  47  HIS   B CG   1 
ATOM   731   N  ND1  . HIS   A 1 48  ? 16.212  -10.993 3.381   1.00 52.11  ?  47  HIS   B ND1  1 
ATOM   732   C  CD2  . HIS   A 1 48  ? 18.380  -10.773 3.135   1.00 51.76  ?  47  HIS   B CD2  1 
ATOM   733   C  CE1  . HIS   A 1 48  ? 16.731  -12.209 3.374   1.00 53.72  ?  47  HIS   B CE1  1 
ATOM   734   N  NE2  . HIS   A 1 48  ? 18.045  -12.104 3.220   1.00 61.64  ?  47  HIS   B NE2  1 
ATOM   735   H  H    . HIS   A 1 48  ? 15.985  -6.238  2.255   1.00 64.86  ?  47  HIS   B H    1 
ATOM   736   H  HA   . HIS   A 1 48  ? 17.326  -8.379  1.235   1.00 61.86  ?  47  HIS   B HA   1 
ATOM   737   H  HB2  . HIS   A 1 48  ? 17.776  -8.155  3.562   1.00 58.87  ?  47  HIS   B HB2  1 
ATOM   738   H  HB3  . HIS   A 1 48  ? 16.227  -8.415  3.807   1.00 58.87  ?  47  HIS   B HB3  1 
ATOM   739   H  HD1  . HIS   A 1 48  ? 15.377  -10.809 3.469   1.00 62.53  ?  47  HIS   B HD1  1 
ATOM   740   H  HD2  . HIS   A 1 48  ? 19.237  -10.425 3.037   1.00 62.11  ?  47  HIS   B HD2  1 
ATOM   741   H  HE1  . HIS   A 1 48  ? 16.256  -13.004 3.462   1.00 64.47  ?  47  HIS   B HE1  1 
ATOM   742   N  N    . ASN   A 1 49  ? 15.183  -9.588  0.772   1.00 55.50  ?  48  ASN   B N    1 
ATOM   743   C  CA   . ASN   A 1 49  ? 13.896  -10.012 0.258   1.00 51.00  ?  48  ASN   B CA   1 
ATOM   744   C  C    . ASN   A 1 49  ? 12.863  -10.098 1.378   1.00 54.23  ?  48  ASN   B C    1 
ATOM   745   O  O    . ASN   A 1 49  ? 11.701  -9.753  1.172   1.00 49.28  ?  48  ASN   B O    1 
ATOM   746   C  CB   . ASN   A 1 49  ? 14.059  -11.333 -0.488  1.00 66.09  ?  48  ASN   B CB   1 
ATOM   747   C  CG   . ASN   A 1 49  ? 14.044  -11.142 -2.012  1.00 73.14  ?  48  ASN   B CG   1 
ATOM   748   O  OD1  . ASN   A 1 49  ? 13.007  -10.799 -2.591  1.00 75.34  ?  48  ASN   B OD1  1 
ATOM   749   N  ND2  . ASN   A 1 49  ? 15.190  -11.336 -2.655  1.00 72.87  ?  48  ASN   B ND2  1 
ATOM   750   H  H    . ASN   A 1 49  ? 15.830  -10.143 0.659   1.00 66.60  ?  48  ASN   B H    1 
ATOM   751   H  HA   . ASN   A 1 49  ? 13.558  -9.369  -0.384  1.00 61.20  ?  48  ASN   B HA   1 
ATOM   752   H  HB2  . ASN   A 1 49  ? 14.906  -11.736 -0.241  1.00 79.31  ?  48  ASN   B HB2  1 
ATOM   753   H  HB3  . ASN   A 1 49  ? 13.329  -11.926 -0.249  1.00 79.31  ?  48  ASN   B HB3  1 
ATOM   754   H  HD21 . ASN   A 1 49  ? 15.896  -11.558 -2.217  1.00 87.44  ?  48  ASN   B HD21 1 
ATOM   755   H  HD22 . ASN   A 1 49  ? 15.226  -11.240 -3.508  1.00 87.44  ?  48  ASN   B HD22 1 
ATOM   756   N  N    . SER   A 1 50  ? 13.276  -10.464 2.585   1.00 55.73  ?  49  SER   B N    1 
ATOM   757   C  CA   . SER   A 1 50  ? 12.325  -10.622 3.680   1.00 48.49  ?  49  SER   B CA   1 
ATOM   758   C  C    . SER   A 1 50  ? 11.737  -9.315  4.199   1.00 40.69  ?  49  SER   B C    1 
ATOM   759   O  O    . SER   A 1 50  ? 10.815  -9.364  5.010   1.00 42.31  ?  49  SER   B O    1 
ATOM   760   C  CB   . SER   A 1 50  ? 13.013  -11.342 4.845   1.00 47.74  ?  49  SER   B CB   1 
ATOM   761   O  OG   . SER   A 1 50  ? 13.999  -10.521 5.460   1.00 51.44  ?  49  SER   B OG   1 
ATOM   762   H  HA   . SER   A 1 50  ? 11.586  -11.157 3.350   1.00 58.18  ?  49  SER   B HA   1 
ATOM   763   H  HB2  . SER   A 1 50  ? 12.343  -11.576 5.508   1.00 57.28  ?  49  SER   B HB2  1 
ATOM   764   H  HB3  . SER   A 1 50  ? 13.440  -12.145 4.508   1.00 57.28  ?  49  SER   B HB3  1 
ATOM   765   N  N    . HIS   A 1 51  ? 12.248  -8.160  3.798   1.00 44.12  ?  50  HIS   B N    1 
ATOM   766   C  CA   . HIS   A 1 51  ? 11.729  -6.907  4.319   1.00 43.31  ?  50  HIS   B CA   1 
ATOM   767   C  C    . HIS   A 1 51  ? 10.475  -6.423  3.579   1.00 45.58  ?  50  HIS   B C    1 
ATOM   768   O  O    . HIS   A 1 51  ? 9.861   -5.440  4.000   1.00 40.91  ?  50  HIS   B O    1 
ATOM   769   C  CB   . HIS   A 1 51  ? 12.802  -5.805  4.257   1.00 44.47  ?  50  HIS   B CB   1 
ATOM   770   C  CG   . HIS   A 1 51  ? 14.060  -6.117  5.016   1.00 52.40  ?  50  HIS   B CG   1 
ATOM   771   N  ND1  . HIS   A 1 51  ? 15.219  -5.374  4.876   1.00 47.43  ?  50  HIS   B ND1  1 
ATOM   772   C  CD2  . HIS   A 1 51  ? 14.349  -7.103  5.900   1.00 50.43  ?  50  HIS   B CD2  1 
ATOM   773   C  CE1  . HIS   A 1 51  ? 16.156  -5.870  5.666   1.00 45.48  ?  50  HIS   B CE1  1 
ATOM   774   N  NE2  . HIS   A 1 51  ? 15.663  -6.936  6.277   1.00 49.19  ?  50  HIS   B NE2  1 
ATOM   775   H  H    . HIS   A 1 51  ? 12.888  -8.077  3.231   1.00 52.95  ?  50  HIS   B H    1 
ATOM   776   H  HA   . HIS   A 1 51  ? 11.498  -7.045  5.251   1.00 51.97  ?  50  HIS   B HA   1 
ATOM   777   H  HB2  . HIS   A 1 51  ? 13.048  -5.665  3.329   1.00 53.37  ?  50  HIS   B HB2  1 
ATOM   778   H  HB3  . HIS   A 1 51  ? 12.431  -4.990  4.628   1.00 53.37  ?  50  HIS   B HB3  1 
ATOM   779   H  HD2  . HIS   A 1 51  ? 13.769  -7.767  6.197   1.00 60.51  ?  50  HIS   B HD2  1 
ATOM   780   H  HE1  . HIS   A 1 51  ? 17.014  -5.529  5.775   1.00 54.58  ?  50  HIS   B HE1  1 
ATOM   781   H  HE2  . HIS   A 1 51  ? 16.094  -7.443  6.822   1.00 59.03  ?  50  HIS   B HE2  1 
ATOM   782   N  N    . GLU   A 1 52  ? 10.103  -7.044  2.466   1.00 41.94  ?  51  GLU   B N    1 
ATOM   783   C  CA   . GLU   A 1 52  ? 8.955   -6.558  1.731   1.00 43.08  ?  51  GLU   B CA   1 
ATOM   784   C  C    . GLU   A 1 52  ? 7.763   -6.603  2.674   1.00 42.52  ?  51  GLU   B C    1 
ATOM   785   O  O    . GLU   A 1 52  ? 7.572   -7.585  3.406   1.00 41.81  ?  51  GLU   B O    1 
ATOM   786   C  CB   . GLU   A 1 52  ? 8.699   -7.396  0.474   1.00 49.65  ?  51  GLU   B CB   1 
ATOM   787   C  CG   . GLU   A 1 52  ? 7.329   -7.124  -0.179  1.00 53.58  ?  51  GLU   B CG   1 
ATOM   788   C  CD   . GLU   A 1 52  ? 7.398   -6.792  -1.675  1.00 56.43  ?  51  GLU   B CD   1 
ATOM   789   O  OE1  . GLU   A 1 52  ? 8.481   -6.554  -2.216  1.00 58.90  ?  51  GLU   B OE1  1 
ATOM   790   O  OE2  . GLU   A 1 52  ? 6.345   -6.770  -2.331  1.00 69.74  -1 51  GLU   B OE2  1 
ATOM   791   H  H    . GLU   A 1 52  ? 10.492  -7.732  2.127   1.00 50.33  ?  51  GLU   B H    1 
ATOM   792   H  HA   . GLU   A 1 52  ? 9.102   -5.652  1.416   1.00 51.69  ?  51  GLU   B HA   1 
ATOM   793   H  HB2  . GLU   A 1 52  ? 9.386   -7.194  -0.181  1.00 59.58  ?  51  GLU   B HB2  1 
ATOM   794   H  HB3  . GLU   A 1 52  ? 8.734   -8.335  0.712   1.00 59.58  ?  51  GLU   B HB3  1 
ATOM   795   H  HG2  . GLU   A 1 52  ? 6.776   -7.914  -0.079  1.00 64.30  ?  51  GLU   B HG2  1 
ATOM   796   H  HG3  . GLU   A 1 52  ? 6.916   -6.370  0.271   1.00 64.30  ?  51  GLU   B HG3  1 
ATOM   797   N  N    . GLY   A 1 53  ? 6.992   -5.518  2.694   1.00 40.13  ?  52  GLY   B N    1 
ATOM   798   C  CA   . GLY   A 1 53  ? 5.831   -5.389  3.566   1.00 36.10  ?  52  GLY   B CA   1 
ATOM   799   C  C    . GLY   A 1 53  ? 6.121   -4.898  4.975   1.00 45.54  ?  52  GLY   B C    1 
ATOM   800   O  O    . GLY   A 1 53  ? 5.232   -4.292  5.586   1.00 40.08  ?  52  GLY   B O    1 
ATOM   801   H  H    . GLY   A 1 53  ? 7.127   -4.827  2.199   1.00 48.16  ?  52  GLY   B H    1 
ATOM   802   H  HA2  . GLY   A 1 53  ? 5.209   -4.765  3.160   1.00 43.32  ?  52  GLY   B HA2  1 
ATOM   803   H  HA3  . GLY   A 1 53  ? 5.405   -6.257  3.640   1.00 43.32  ?  52  GLY   B HA3  1 
ATOM   804   N  N    . LYS   A 1 54  ? 7.342   -5.131  5.502   1.00 39.25  ?  53  LYS   B N    1 
ATOM   805   C  CA   . LYS   A 1 54  ? 7.692   -4.713  6.856   1.00 35.69  ?  53  LYS   B CA   1 
ATOM   806   C  C    . LYS   A 1 54  ? 7.639   -3.186  6.986   1.00 36.43  ?  53  LYS   B C    1 
ATOM   807   O  O    . LYS   A 1 54  ? 7.610   -2.448  5.998   1.00 31.80  ?  53  LYS   B O    1 
ATOM   808   C  CB   . LYS   A 1 54  ? 9.098   -5.185  7.270   1.00 35.96  ?  53  LYS   B CB   1 
ATOM   809   C  CG   . LYS   A 1 54  ? 9.366   -6.687  7.136   1.00 44.54  ?  53  LYS   B CG   1 
ATOM   810   C  CD   . LYS   A 1 54  ? 8.964   -7.477  8.350   1.00 47.85  ?  53  LYS   B CD   1 
ATOM   811   C  CE   . LYS   A 1 54  ? 9.715   -8.800  8.462   1.00 45.36  ?  53  LYS   B CE   1 
ATOM   812   N  NZ   . LYS   A 1 54  ? 10.898  -8.614  9.357   1.00 56.92  ?  53  LYS   B NZ   1 
ATOM   813   H  H    . LYS   A 1 54  ? 7.981   -5.531  5.087   1.00 47.10  ?  53  LYS   B H    1 
ATOM   814   H  HA   . LYS   A 1 54  ? 7.049   -5.118  7.459   1.00 42.83  ?  53  LYS   B HA   1 
ATOM   815   H  HB2  . LYS   A 1 54  ? 9.748   -4.726  6.715   1.00 43.16  ?  53  LYS   B HB2  1 
ATOM   816   H  HB3  . LYS   A 1 54  ? 9.234   -4.951  8.202   1.00 43.16  ?  53  LYS   B HB3  1 
ATOM   817   H  HG2  . LYS   A 1 54  ? 8.865   -7.029  6.380   1.00 53.45  ?  53  LYS   B HG2  1 
ATOM   818   H  HG3  . LYS   A 1 54  ? 10.316  -6.825  6.995   1.00 53.45  ?  53  LYS   B HG3  1 
ATOM   819   H  HD2  . LYS   A 1 54  ? 9.153   -6.955  9.146   1.00 57.41  ?  53  LYS   B HD2  1 
ATOM   820   H  HD3  . LYS   A 1 54  ? 8.015   -7.673  8.301   1.00 57.41  ?  53  LYS   B HD3  1 
ATOM   821   H  HE2  . LYS   A 1 54  ? 9.135   -9.478  8.842   1.00 54.43  ?  53  LYS   B HE2  1 
ATOM   822   H  HE3  . LYS   A 1 54  ? 10.023  -9.080  7.586   1.00 54.43  ?  53  LYS   B HE3  1 
ATOM   823   H  HZ1  . LYS   A 1 54  ? 11.393  -9.354  9.365   1.00 68.30  ?  53  LYS   B HZ1  1 
ATOM   824   H  HZ2  . LYS   A 1 54  ? 11.397  -7.936  9.065   1.00 68.30  ?  53  LYS   B HZ2  1 
ATOM   825   H  HZ3  . LYS   A 1 54  ? 10.628  -8.438  10.186  1.00 68.30  ?  53  LYS   B HZ3  1 
ATOM   826   N  N    . THR   A 1 55  ? 7.607   -2.716  8.235   1.00 35.40  ?  54  THR   B N    1 
ATOM   827   C  CA   . THR   A 1 55  ? 7.508   -1.300  8.556   1.00 32.34  ?  54  THR   B CA   1 
ATOM   828   C  C    . THR   A 1 55  ? 8.834   -0.830  9.151   1.00 37.16  ?  54  THR   B C    1 
ATOM   829   O  O    . THR   A 1 55  ? 9.549   -1.594  9.794   1.00 38.51  ?  54  THR   B O    1 
ATOM   830   C  CB   . THR   A 1 55  ? 6.320   -1.059  9.517   1.00 36.93  ?  54  THR   B CB   1 
ATOM   831   O  OG1  . THR   A 1 55  ? 5.060   -1.359  8.862   1.00 38.60  ?  54  THR   B OG1  1 
ATOM   832   C  CG2  . THR   A 1 55  ? 6.275   0.386   9.999   1.00 35.05  ?  54  THR   B CG2  1 
ATOM   833   H  H    . THR   A 1 55  ? 7.643   -3.219  8.932   1.00 42.48  ?  54  THR   B H    1 
ATOM   834   H  HA   . THR   A 1 55  ? 7.346   -0.764  7.764   1.00 38.81  ?  54  THR   B HA   1 
ATOM   835   H  HB   . THR   A 1 55  ? 6.439   -1.640  10.285  1.00 44.32  ?  54  THR   B HB   1 
ATOM   836   H  HG1  . THR   A 1 55  ? 4.419   -1.105  9.341   1.00 46.32  ?  54  THR   B HG1  1 
ATOM   837   H  HG21 . THR   A 1 55  ? 5.436   0.559   10.454  1.00 42.06  ?  54  THR   B HG21 1 
ATOM   838   H  HG22 . THR   A 1 55  ? 7.006   0.554   10.614  1.00 42.06  ?  54  THR   B HG22 1 
ATOM   839   H  HG23 . THR   A 1 55  ? 6.354   0.990   9.244   1.00 42.06  ?  54  THR   B HG23 1 
ATOM   840   N  N    . PHE   A 1 56  ? 9.173   0.429   8.907   1.00 37.72  ?  55  PHE   B N    1 
ATOM   841   C  CA   . PHE   A 1 56  ? 10.486  0.958   9.230   1.00 33.56  ?  55  PHE   B CA   1 
ATOM   842   C  C    . PHE   A 1 56  ? 10.306  2.331   9.856   1.00 38.60  ?  55  PHE   B C    1 
ATOM   843   O  O    . PHE   A 1 56  ? 9.605   3.173   9.286   1.00 37.56  ?  55  PHE   B O    1 
ATOM   844   C  CB   . PHE   A 1 56  ? 11.357  1.107   7.960   1.00 41.13  ?  55  PHE   B CB   1 
ATOM   845   C  CG   . PHE   A 1 56  ? 11.950  -0.181  7.450   1.00 36.94  ?  55  PHE   B CG   1 
ATOM   846   C  CD1  . PHE   A 1 56  ? 11.200  -1.043  6.663   1.00 36.99  ?  55  PHE   B CD1  1 
ATOM   847   C  CD2  . PHE   A 1 56  ? 13.248  -0.534  7.772   1.00 37.83  ?  55  PHE   B CD2  1 
ATOM   848   C  CE1  . PHE   A 1 56  ? 11.742  -2.224  6.196   1.00 42.42  ?  55  PHE   B CE1  1 
ATOM   849   C  CE2  . PHE   A 1 56  ? 13.800  -1.728  7.302   1.00 37.94  ?  55  PHE   B CE2  1 
ATOM   850   C  CZ   . PHE   A 1 56  ? 13.053  -2.565  6.519   1.00 41.28  ?  55  PHE   B CZ   1 
ATOM   851   H  H    . PHE   A 1 56  ? 8.647   1.006   8.548   1.00 45.26  ?  55  PHE   B H    1 
ATOM   852   H  HA   . PHE   A 1 56  ? 10.932  0.364   9.854   1.00 40.27  ?  55  PHE   B HA   1 
ATOM   853   H  HB2  . PHE   A 1 56  ? 10.807  1.477   7.251   1.00 49.36  ?  55  PHE   B HB2  1 
ATOM   854   H  HB3  . PHE   A 1 56  ? 12.091  1.709   8.158   1.00 49.36  ?  55  PHE   B HB3  1 
ATOM   855   H  HD1  . PHE   A 1 56  ? 10.322  -0.824  6.448   1.00 44.39  ?  55  PHE   B HD1  1 
ATOM   856   H  HD2  . PHE   A 1 56  ? 13.759  0.030   8.307   1.00 45.40  ?  55  PHE   B HD2  1 
ATOM   857   H  HE1  . PHE   A 1 56  ? 11.231  -2.791  5.666   1.00 50.90  ?  55  PHE   B HE1  1 
ATOM   858   H  HE2  . PHE   A 1 56  ? 14.675  -1.954  7.522   1.00 45.53  ?  55  PHE   B HE2  1 
ATOM   859   H  HZ   . PHE   A 1 56  ? 13.420  -3.359  6.202   1.00 49.54  ?  55  PHE   B HZ   1 
ATOM   860   N  N    . TYR   A 1 57  ? 10.928  2.579   11.004  1.00 39.01  ?  56  TYR   B N    1 
ATOM   861   C  CA   . TYR   A 1 57  ? 10.948  3.936   11.531  1.00 38.40  ?  56  TYR   B CA   1 
ATOM   862   C  C    . TYR   A 1 57  ? 12.027  4.751   10.834  1.00 38.38  ?  56  TYR   B C    1 
ATOM   863   O  O    . TYR   A 1 57  ? 13.108  4.237   10.538  1.00 39.78  ?  56  TYR   B O    1 
ATOM   864   C  CB   . TYR   A 1 57  ? 11.222  3.947   13.032  1.00 45.44  ?  56  TYR   B CB   1 
ATOM   865   C  CG   . TYR   A 1 57  ? 10.037  3.579   13.934  1.00 38.22  ?  56  TYR   B CG   1 
ATOM   866   C  CD1  . TYR   A 1 57  ? 9.365   4.552   14.666  1.00 40.10  ?  56  TYR   B CD1  1 
ATOM   867   C  CD2  . TYR   A 1 57  ? 9.632   2.251   14.081  1.00 34.06  ?  56  TYR   B CD2  1 
ATOM   868   C  CE1  . TYR   A 1 57  ? 8.333   4.216   15.497  1.00 38.58  ?  56  TYR   B CE1  1 
ATOM   869   C  CE2  . TYR   A 1 57  ? 8.615   1.906   14.910  1.00 37.40  ?  56  TYR   B CE2  1 
ATOM   870   C  CZ   . TYR   A 1 57  ? 7.953   2.899   15.618  1.00 40.98  ?  56  TYR   B CZ   1 
ATOM   871   O  OH   . TYR   A 1 57  ? 6.896   2.591   16.456  1.00 43.49  ?  56  TYR   B OH   1 
ATOM   872   H  H    . TYR   A 1 57  ? 11.335  1.992   11.483  1.00 46.82  ?  56  TYR   B H    1 
ATOM   873   H  HA   . TYR   A 1 57  ? 10.080  4.340   11.377  1.00 46.08  ?  56  TYR   B HA   1 
ATOM   874   H  HB2  . TYR   A 1 57  ? 11.930  3.311   13.216  1.00 54.53  ?  56  TYR   B HB2  1 
ATOM   875   H  HB3  . TYR   A 1 57  ? 11.505  4.841   13.282  1.00 54.53  ?  56  TYR   B HB3  1 
ATOM   876   H  HD1  . TYR   A 1 57  ? 9.621   5.443   14.589  1.00 48.12  ?  56  TYR   B HD1  1 
ATOM   877   H  HD2  . TYR   A 1 57  ? 10.069  1.587   13.599  1.00 40.88  ?  56  TYR   B HD2  1 
ATOM   878   H  HE1  . TYR   A 1 57  ? 7.888   4.875   15.980  1.00 46.30  ?  56  TYR   B HE1  1 
ATOM   879   H  HE2  . TYR   A 1 57  ? 8.365   1.015   15.003  1.00 44.89  ?  56  TYR   B HE2  1 
ATOM   880   H  HH   . TYR   A 1 57  ? 6.790   1.758   16.491  1.00 52.18  ?  56  TYR   B HH   1 
ATOM   881   N  N    . VAL   A 1 58  ? 11.737  6.026   10.581  1.00 34.64  ?  57  VAL   B N    1 
ATOM   882   C  CA   . VAL   A 1 58  ? 12.689  6.941   9.972   1.00 45.58  ?  57  VAL   B CA   1 
ATOM   883   C  C    . VAL   A 1 58  ? 12.550  8.274   10.679  1.00 49.08  ?  57  VAL   B C    1 
ATOM   884   O  O    . VAL   A 1 58  ? 11.569  8.527   11.371  1.00 41.23  ?  57  VAL   B O    1 
ATOM   885   C  CB   . VAL   A 1 58  ? 12.466  7.136   8.458   1.00 50.94  ?  57  VAL   B CB   1 
ATOM   886   C  CG1  . VAL   A 1 58  ? 12.200  5.779   7.785   1.00 52.35  ?  57  VAL   B CG1  1 
ATOM   887   C  CG2  . VAL   A 1 58  ? 11.290  8.099   8.208   1.00 46.14  ?  57  VAL   B CG2  1 
ATOM   888   H  H    . VAL   A 1 58  ? 10.978  6.388   10.759  1.00 41.57  ?  57  VAL   B H    1 
ATOM   889   H  HA   . VAL   A 1 58  ? 13.585  6.590   10.094  1.00 54.69  ?  57  VAL   B HA   1 
ATOM   890   H  HB   . VAL   A 1 58  ? 13.263  7.524   8.067   1.00 61.13  ?  57  VAL   B HB   1 
ATOM   891   H  HG11 . VAL   A 1 58  ? 12.065  5.919   6.835   1.00 62.82  ?  57  VAL   B HG11 1 
ATOM   892   H  HG12 . VAL   A 1 58  ? 12.965  5.200   7.929   1.00 62.82  ?  57  VAL   B HG12 1 
ATOM   893   H  HG13 . VAL   A 1 58  ? 11.407  5.381   8.177   1.00 62.82  ?  57  VAL   B HG13 1 
ATOM   894   H  HG21 . VAL   A 1 58  ? 11.130  8.161   7.253   1.00 55.36  ?  57  VAL   B HG21 1 
ATOM   895   H  HG22 . VAL   A 1 58  ? 10.500  7.755   8.653   1.00 55.36  ?  57  VAL   B HG22 1 
ATOM   896   H  HG23 . VAL   A 1 58  ? 11.516  8.972   8.563   1.00 55.36  ?  57  VAL   B HG23 1 
ATOM   897   N  N    . LEU   A 1 59  ? 13.522  9.148   10.456  1.00 50.85  ?  58  LEU   B N    1 
ATOM   898   C  CA   . LEU   A 1 59  ? 13.553  10.426  11.158  1.00 54.50  ?  58  LEU   B CA   1 
ATOM   899   C  C    . LEU   A 1 59  ? 12.689  11.469  10.450  1.00 58.07  ?  58  LEU   B C    1 
ATOM   900   O  O    . LEU   A 1 59  ? 12.640  11.504  9.225   1.00 56.57  ?  58  LEU   B O    1 
ATOM   901   C  CB   . LEU   A 1 59  ? 14.985  10.931  11.260  1.00 57.70  ?  58  LEU   B CB   1 
ATOM   902   C  CG   . LEU   A 1 59  ? 15.761  10.420  12.490  1.00 57.47  ?  58  LEU   B CG   1 
ATOM   903   C  CD1  . LEU   A 1 59  ? 15.691  8.921   12.673  1.00 59.76  ?  58  LEU   B CD1  1 
ATOM   904   C  CD2  . LEU   A 1 59  ? 17.219  10.866  12.373  1.00 59.23  ?  58  LEU   B CD2  1 
ATOM   905   H  H    . LEU   A 1 59  ? 14.173  9.029   9.907   1.00 61.02  ?  58  LEU   B H    1 
ATOM   906   H  HA   . LEU   A 1 59  ? 13.195  10.312  12.052  1.00 65.40  ?  58  LEU   B HA   1 
ATOM   907   H  HB2  . LEU   A 1 59  ? 15.469  10.646  10.469  1.00 69.24  ?  58  LEU   B HB2  1 
ATOM   908   H  HB3  . LEU   A 1 59  ? 14.967  11.900  11.306  1.00 69.24  ?  58  LEU   B HB3  1 
ATOM   909   H  HG   . LEU   A 1 59  ? 15.347  10.800  13.281  1.00 68.96  ?  58  LEU   B HG   1 
ATOM   910   H  HD11 . LEU   A 1 59  ? 16.340  8.653   13.342  1.00 71.71  ?  58  LEU   B HD11 1 
ATOM   911   H  HD12 . LEU   A 1 59  ? 14.798  8.679   12.962  1.00 71.71  ?  58  LEU   B HD12 1 
ATOM   912   H  HD13 . LEU   A 1 59  ? 15.892  8.490   11.827  1.00 71.71  ?  58  LEU   B HD13 1 
ATOM   913   H  HD21 . LEU   A 1 59  ? 17.795  10.149  12.683  1.00 71.08  ?  58  LEU   B HD21 1 
ATOM   914   H  HD22 . LEU   A 1 59  ? 17.414  11.069  11.445  1.00 71.08  ?  58  LEU   B HD22 1 
ATOM   915   H  HD23 . LEU   A 1 59  ? 17.353  11.656  12.920  1.00 71.08  ?  58  LEU   B HD23 1 
ATOM   916   N  N    . PRO   A 1 60  ? 11.993  12.314  11.201  1.00 55.74  ?  59  PRO   B N    1 
ATOM   917   C  CA   . PRO   A 1 60  ? 11.228  13.394  10.559  1.00 56.48  ?  59  PRO   B CA   1 
ATOM   918   C  C    . PRO   A 1 60  ? 12.076  14.345  9.725   1.00 65.90  ?  59  PRO   B C    1 
ATOM   919   O  O    . PRO   A 1 60  ? 12.671  15.291  10.254  1.00 65.38  ?  59  PRO   B O    1 
ATOM   920   C  CB   . PRO   A 1 60  ? 10.602  14.131  11.753  1.00 59.39  ?  59  PRO   B CB   1 
ATOM   921   C  CG   . PRO   A 1 60  ? 10.485  13.057  12.853  1.00 55.14  ?  59  PRO   B CG   1 
ATOM   922   C  CD   . PRO   A 1 60  ? 11.726  12.216  12.659  1.00 54.53  ?  59  PRO   B CD   1 
ATOM   923   H  HA   . PRO   A 1 60  ? 10.541  13.007  9.994   1.00 67.78  ?  59  PRO   B HA   1 
ATOM   924   H  HB2  . PRO   A 1 60  ? 11.179  14.857  12.035  1.00 71.27  ?  59  PRO   B HB2  1 
ATOM   925   H  HB3  . PRO   A 1 60  ? 9.729   14.476  11.509  1.00 71.27  ?  59  PRO   B HB3  1 
ATOM   926   H  HG2  . PRO   A 1 60  ? 10.475  13.473  13.730  1.00 66.17  ?  59  PRO   B HG2  1 
ATOM   927   H  HG3  . PRO   A 1 60  ? 9.680   12.531  12.727  1.00 66.17  ?  59  PRO   B HG3  1 
ATOM   928   H  HD2  . PRO   A 1 60  ? 12.468  12.575  13.170  1.00 65.44  ?  59  PRO   B HD2  1 
ATOM   929   H  HD3  . PRO   A 1 60  ? 11.561  11.295  12.917  1.00 65.44  ?  59  PRO   B HD3  1 
ATOM   930   N  N    . ASN   A 1 61  ? 12.095  14.126  8.412   1.00 72.27  ?  60  ASN   B N    1 
ATOM   931   C  CA   . ASN   A 1 61  ? 12.879  14.932  7.497   1.00 67.36  ?  60  ASN   B CA   1 
ATOM   932   C  C    . ASN   A 1 61  ? 12.064  15.890  6.632   1.00 70.77  ?  60  ASN   B C    1 
ATOM   933   O  O    . ASN   A 1 61  ? 12.669  16.712  5.934   1.00 74.21  ?  60  ASN   B O    1 
ATOM   934   C  CB   . ASN   A 1 61  ? 13.709  14.010  6.585   1.00 65.09  ?  60  ASN   B CB   1 
ATOM   935   C  CG   . ASN   A 1 61  ? 12.849  13.098  5.736   1.00 83.46  ?  60  ASN   B CG   1 
ATOM   936   O  OD1  . ASN   A 1 61  ? 12.196  13.550  4.789   1.00 79.89  ?  60  ASN   B OD1  1 
ATOM   937   N  ND2  . ASN   A 1 61  ? 12.839  11.810  6.068   1.00 110.26 ?  60  ASN   B ND2  1 
ATOM   938   H  H    . ASN   A 1 61  ? 11.650  13.501  8.024   1.00 86.73  ?  60  ASN   B H    1 
ATOM   939   H  HA   . ASN   A 1 61  ? 13.484  15.481  8.020   1.00 80.84  ?  60  ASN   B HA   1 
ATOM   940   H  HB2  . ASN   A 1 61  ? 14.247  14.556  5.989   1.00 78.10  ?  60  ASN   B HB2  1 
ATOM   941   H  HB3  . ASN   A 1 61  ? 14.284  13.455  7.134   1.00 78.10  ?  60  ASN   B HB3  1 
ATOM   942   H  HD21 . ASN   A 1 61  ? 13.307  11.535  6.736   1.00 132.31 ?  60  ASN   B HD21 1 
ATOM   943   H  HD22 . ASN   A 1 61  ? 12.366  11.253  5.616   1.00 132.31 ?  60  ASN   B HD22 1 
ATOM   944   N  N    . ASP   A 1 62  ? 10.730  15.825  6.658   1.00 63.28  ?  61  ASP   B N    1 
ATOM   945   C  CA   . ASP   A 1 62  ? 9.870   16.799  5.988   1.00 65.62  ?  61  ASP   B CA   1 
ATOM   946   C  C    . ASP   A 1 62  ? 8.853   17.333  6.997   1.00 68.78  ?  61  ASP   B C    1 
ATOM   947   O  O    . ASP   A 1 62  ? 8.786   16.871  8.138   1.00 68.09  ?  61  ASP   B O    1 
ATOM   948   C  CB   . ASP   A 1 62  ? 9.208   16.199  4.719   1.00 66.86  ?  61  ASP   B CB   1 
ATOM   949   C  CG   . ASP   A 1 62  ? 7.991   15.304  4.999   1.00 74.81  ?  61  ASP   B CG   1 
ATOM   950   O  OD1  . ASP   A 1 62  ? 7.471   15.264  6.139   1.00 76.82  ?  61  ASP   B OD1  1 
ATOM   951   O  OD2  . ASP   A 1 62  ? 7.540   14.623  4.035   1.00 69.26  -1 61  ASP   B OD2  1 
ATOM   952   H  H    . ASP   A 1 62  ? 10.291  15.210  7.068   1.00 75.93  ?  61  ASP   B H    1 
ATOM   953   H  HA   . ASP   A 1 62  ? 10.389  17.559  5.683   1.00 78.75  ?  61  ASP   B HA   1 
ATOM   954   H  HB2  . ASP   A 1 62  ? 8.911   16.927  4.151   1.00 80.24  ?  61  ASP   B HB2  1 
ATOM   955   H  HB3  . ASP   A 1 62  ? 9.866   15.660  4.252   1.00 80.24  ?  61  ASP   B HB3  1 
ATOM   956   N  N    . ASP   A 1 63  ? 8.060   18.327  6.582   1.00 65.93  ?  62  ASP   B N    1 
ATOM   957   C  CA   . ASP   A 1 63  ? 7.130   18.966  7.518   1.00 72.25  ?  62  ASP   B CA   1 
ATOM   958   C  C    . ASP   A 1 63  ? 5.991   18.027  7.914   1.00 70.73  ?  62  ASP   B C    1 
ATOM   959   O  O    . ASP   A 1 63  ? 5.605   17.966  9.088   1.00 59.33  ?  62  ASP   B O    1 
ATOM   960   C  CB   . ASP   A 1 63  ? 6.570   20.259  6.917   1.00 75.97  ?  62  ASP   B CB   1 
ATOM   961   C  CG   . ASP   A 1 63  ? 7.589   21.403  6.931   1.00 86.94  ?  62  ASP   B CG   1 
ATOM   962   O  OD1  . ASP   A 1 63  ? 8.786   21.138  7.207   1.00 80.21  ?  62  ASP   B OD1  1 
ATOM   963   O  OD2  . ASP   A 1 63  ? 7.196   22.563  6.673   1.00 145.85 -1 62  ASP   B OD2  1 
ATOM   964   H  H    . ASP   A 1 63  ? 8.041   18.644  5.782   1.00 79.12  ?  62  ASP   B H    1 
ATOM   965   H  HA   . ASP   A 1 63  ? 7.622   19.195  8.323   1.00 86.70  ?  62  ASP   B HA   1 
ATOM   966   H  HB2  . ASP   A 1 63  ? 6.314   20.095  5.996   1.00 91.16  ?  62  ASP   B HB2  1 
ATOM   967   H  HB3  . ASP   A 1 63  ? 5.797   20.539  7.432   1.00 91.16  ?  62  ASP   B HB3  1 
ATOM   968   N  N    . THR   A 1 64  ? 5.437   17.291  6.949   1.00 74.33  ?  63  THR   B N    1 
ATOM   969   C  CA   . THR   A 1 64  ? 4.397   16.319  7.265   1.00 68.53  ?  63  THR   B CA   1 
ATOM   970   C  C    . THR   A 1 64  ? 4.885   15.323  8.309   1.00 58.66  ?  63  THR   B C    1 
ATOM   971   O  O    . THR   A 1 64  ? 4.135   14.906  9.193   1.00 53.96  ?  63  THR   B O    1 
ATOM   972   C  CB   . THR   A 1 64  ? 3.964   15.582  5.993   1.00 73.82  ?  63  THR   B CB   1 
ATOM   973   O  OG1  . THR   A 1 64  ? 3.428   16.520  5.052   1.00 59.16  ?  63  THR   B OG1  1 
ATOM   974   C  CG2  . THR   A 1 64  ? 2.922   14.521  6.309   1.00 82.08  ?  63  THR   B CG2  1 
ATOM   975   H  H    . THR   A 1 64  ? 5.644   17.336  6.115   1.00 89.20  ?  63  THR   B H    1 
ATOM   976   H  HA   . THR   A 1 64  ? 3.626   16.787  7.622   1.00 82.24  ?  63  THR   B HA   1 
ATOM   977   H  HB   . THR   A 1 64  ? 4.733   15.138  5.602   1.00 88.59  ?  63  THR   B HB   1 
ATOM   978   H  HG1  . THR   A 1 64  ? 3.424   16.184  4.282   1.00 70.99  ?  63  THR   B HG1  1 
ATOM   979   H  HG21 . THR   A 1 64  ? 2.672   14.049  5.499   1.00 98.49  ?  63  THR   B HG21 1 
ATOM   980   H  HG22 . THR   A 1 64  ? 3.280   13.884  6.947   1.00 98.49  ?  63  THR   B HG22 1 
ATOM   981   H  HG23 . THR   A 1 64  ? 2.131   14.936  6.688   1.00 98.49  ?  63  THR   B HG23 1 
ATOM   982   N  N    . LEU   A 1 65  ? 6.131   14.906  8.206   1.00 63.19  ?  64  LEU   B N    1 
ATOM   983   C  CA   . LEU   A 1 65  ? 6.624   13.879  9.109   1.00 63.24  ?  64  LEU   B CA   1 
ATOM   984   C  C    . LEU   A 1 65  ? 6.870   14.422  10.509  1.00 57.58  ?  64  LEU   B C    1 
ATOM   985   O  O    . LEU   A 1 65  ? 6.665   13.699  11.495  1.00 52.62  ?  64  LEU   B O    1 
ATOM   986   C  CB   . LEU   A 1 65  ? 7.899   13.272  8.531   1.00 62.61  ?  64  LEU   B CB   1 
ATOM   987   C  CG   . LEU   A 1 65  ? 7.680   11.902  7.897   1.00 62.30  ?  64  LEU   B CG   1 
ATOM   988   C  CD1  . LEU   A 1 65  ? 7.324   10.897  8.987   1.00 60.18  ?  64  LEU   B CD1  1 
ATOM   989   C  CD2  . LEU   A 1 65  ? 6.574   11.883  6.881   1.00 70.67  ?  64  LEU   B CD2  1 
ATOM   990   H  H    . LEU   A 1 65  ? 6.705   15.194  7.634   1.00 75.83  ?  64  LEU   B H    1 
ATOM   991   H  HA   . LEU   A 1 65  ? 5.965   13.172  9.189   1.00 75.88  ?  64  LEU   B HA   1 
ATOM   992   H  HB2  . LEU   A 1 65  ? 8.246   13.865  7.847   1.00 75.13  ?  64  LEU   B HB2  1 
ATOM   993   H  HB3  . LEU   A 1 65  ? 8.548   13.171  9.244   1.00 75.13  ?  64  LEU   B HB3  1 
ATOM   994   H  HG   . LEU   A 1 65  ? 8.503   11.668  7.441   1.00 74.76  ?  64  LEU   B HG   1 
ATOM   995   H  HD11 . LEU   A 1 65  ? 7.211   10.021  8.584   1.00 72.21  ?  64  LEU   B HD11 1 
ATOM   996   H  HD12 . LEU   A 1 65  ? 8.041   10.870  9.639   1.00 72.21  ?  64  LEU   B HD12 1 
ATOM   997   H  HD13 . LEU   A 1 65  ? 6.498   11.173  9.414   1.00 72.21  ?  64  LEU   B HD13 1 
ATOM   998   H  HD21 . LEU   A 1 65  ? 6.493   10.986  6.519   1.00 84.81  ?  64  LEU   B HD21 1 
ATOM   999   H  HD22 . LEU   A 1 65  ? 5.744   12.141  7.313   1.00 84.81  ?  64  LEU   B HD22 1 
ATOM   1000  H  HD23 . LEU   A 1 65  ? 6.786   12.508  6.171   1.00 84.81  ?  64  LEU   B HD23 1 
ATOM   1001  N  N    . ARG   A 1 66  ? 7.305   15.674  10.632  1.00 56.15  ?  65  ARG   B N    1 
ATOM   1002  C  CA   . ARG   A 1 66  ? 7.518   16.167  11.981  1.00 56.68  ?  65  ARG   B CA   1 
ATOM   1003  C  C    . ARG   A 1 66  ? 6.225   16.656  12.622  1.00 48.75  ?  65  ARG   B C    1 
ATOM   1004  O  O    . ARG   A 1 66  ? 6.154   16.787  13.841  1.00 48.52  ?  65  ARG   B O    1 
ATOM   1005  C  CB   . ARG   A 1 66  ? 8.606   17.239  12.018  1.00 60.43  ?  65  ARG   B CB   1 
ATOM   1006  C  CG   . ARG   A 1 66  ? 8.727   18.210  10.866  1.00 59.36  ?  65  ARG   B CG   1 
ATOM   1007  C  CD   . ARG   A 1 66  ? 9.853   19.248  11.166  1.00 59.92  ?  65  ARG   B CD   1 
ATOM   1008  N  NE   . ARG   A 1 66  ? 11.090  18.918  10.472  1.00 66.17  ?  65  ARG   B NE   1 
ATOM   1009  C  CZ   . ARG   A 1 66  ? 11.326  19.196  9.195   1.00 67.24  ?  65  ARG   B CZ   1 
ATOM   1010  N  NH1  . ARG   A 1 66  ? 12.410  18.751  8.576   1.00 62.40  ?  65  ARG   B NH1  1 
ATOM   1011  N  NH2  . ARG   A 1 66  ? 10.448  19.932  8.520   1.00 70.61  ?  65  ARG   B NH2  1 
ATOM   1012  H  H    . ARG   A 1 66  ? 7.473   16.220  9.989   1.00 67.38  ?  65  ARG   B H    1 
ATOM   1013  H  HA   . ARG   A 1 66  ? 7.859   15.445  12.532  1.00 68.01  ?  65  ARG   B HA   1 
ATOM   1014  H  HB2  . ARG   A 1 66  ? 8.458   17.776  12.812  1.00 72.52  ?  65  ARG   B HB2  1 
ATOM   1015  H  HB3  . ARG   A 1 66  ? 9.460   16.783  12.080  1.00 72.52  ?  65  ARG   B HB3  1 
ATOM   1016  H  HG2  . ARG   A 1 66  ? 8.955   17.729  10.054  1.00 71.23  ?  65  ARG   B HG2  1 
ATOM   1017  H  HG3  . ARG   A 1 66  ? 7.890   18.684  10.747  1.00 71.23  ?  65  ARG   B HG3  1 
ATOM   1018  H  HD2  . ARG   A 1 66  ? 9.564   20.126  10.873  1.00 71.90  ?  65  ARG   B HD2  1 
ATOM   1019  H  HD3  . ARG   A 1 66  ? 10.032  19.258  12.119  1.00 71.90  ?  65  ARG   B HD3  1 
ATOM   1020  H  HE   . ARG   A 1 66  ? 11.707  18.517  10.917  1.00 79.41  ?  65  ARG   B HE   1 
ATOM   1021  H  HH11 . ARG   A 1 66  ? 12.980  18.268  9.002   1.00 74.89  ?  65  ARG   B HH11 1 
ATOM   1022  H  HH12 . ARG   A 1 66  ? 12.542  18.943  7.749   1.00 74.89  ?  65  ARG   B HH12 1 
ATOM   1023  H  HH21 . ARG   A 1 66  ? 9.738   20.221  8.910   1.00 84.74  ?  65  ARG   B HH21 1 
ATOM   1024  H  HH22 . ARG   A 1 66  ? 10.590  20.119  7.692   1.00 84.74  ?  65  ARG   B HH22 1 
ATOM   1025  N  N    . VAL   A 1 67  ? 5.177   16.890  11.850  1.00 56.58  ?  66  VAL   B N    1 
ATOM   1026  C  CA   . VAL   A 1 67  ? 3.864   17.084  12.457  1.00 49.45  ?  66  VAL   B CA   1 
ATOM   1027  C  C    . VAL   A 1 67  ? 3.376   15.783  13.097  1.00 50.05  ?  66  VAL   B C    1 
ATOM   1028  O  O    . VAL   A 1 67  ? 2.993   15.753  14.271  1.00 43.84  ?  66  VAL   B O    1 
ATOM   1029  C  CB   . VAL   A 1 67  ? 2.872   17.614  11.407  1.00 51.18  ?  66  VAL   B CB   1 
ATOM   1030  C  CG1  . VAL   A 1 67  ? 1.438   17.460  11.889  1.00 41.10  ?  66  VAL   B CG1  1 
ATOM   1031  C  CG2  . VAL   A 1 67  ? 3.191   19.100  11.087  1.00 57.15  ?  66  VAL   B CG2  1 
ATOM   1032  H  H    . VAL   A 1 67  ? 5.195   16.941  10.992  1.00 67.90  ?  66  VAL   B H    1 
ATOM   1033  H  HA   . VAL   A 1 67  ? 3.937   17.747  13.161  1.00 59.34  ?  66  VAL   B HA   1 
ATOM   1034  H  HB   . VAL   A 1 67  ? 2.963   17.095  10.593  1.00 61.41  ?  66  VAL   B HB   1 
ATOM   1035  H  HG11 . VAL   A 1 67  ? 0.848   17.931  11.280  1.00 49.32  ?  66  VAL   B HG11 1 
ATOM   1036  H  HG12 . VAL   A 1 67  ? 1.211   16.517  11.907  1.00 49.32  ?  66  VAL   B HG12 1 
ATOM   1037  H  HG13 . VAL   A 1 67  ? 1.362   17.836  12.780  1.00 49.32  ?  66  VAL   B HG13 1 
ATOM   1038  H  HG21 . VAL   A 1 67  ? 2.545   19.430  10.444  1.00 68.58  ?  66  VAL   B HG21 1 
ATOM   1039  H  HG22 . VAL   A 1 67  ? 3.138   19.617  11.906  1.00 68.58  ?  66  VAL   B HG22 1 
ATOM   1040  H  HG23 . VAL   A 1 67  ? 4.086   19.158  10.717  1.00 68.58  ?  66  VAL   B HG23 1 
ATOM   1041  N  N    . GLU   A 1 68  ? 3.408   14.685  12.342  1.00 46.03  ?  67  GLU   B N    1 
ATOM   1042  C  CA   . GLU   A 1 68  ? 3.028   13.390  12.895  1.00 49.58  ?  67  GLU   B CA   1 
ATOM   1043  C  C    . GLU   A 1 68  ? 3.853   13.041  14.137  1.00 43.97  ?  67  GLU   B C    1 
ATOM   1044  O  O    . GLU   A 1 68  ? 3.316   12.469  15.091  1.00 42.83  ?  67  GLU   B O    1 
ATOM   1045  C  CB   . GLU   A 1 68  ? 3.141   12.321  11.798  1.00 46.75  ?  67  GLU   B CB   1 
ATOM   1046  C  CG   . GLU   A 1 68  ? 2.063   12.545  10.700  1.00 59.80  ?  67  GLU   B CG   1 
ATOM   1047  C  CD   . GLU   A 1 68  ? 2.262   11.764  9.406   1.00 74.72  ?  67  GLU   B CD   1 
ATOM   1048  O  OE1  . GLU   A 1 68  ? 3.187   10.941  9.350   1.00 74.14  ?  67  GLU   B OE1  1 
ATOM   1049  O  OE2  . GLU   A 1 68  ? 1.461   11.987  8.427   1.00 73.65  -1 67  GLU   B OE2  1 
ATOM   1050  H  H    . GLU   A 1 68  ? 3.643   14.663  11.515  1.00 55.23  ?  67  GLU   B H    1 
ATOM   1051  H  HA   . GLU   A 1 68  ? 2.103   13.416  13.185  1.00 59.50  ?  67  GLU   B HA   1 
ATOM   1052  H  HB2  . GLU   A 1 68  ? 4.018   12.372  11.385  1.00 56.10  ?  67  GLU   B HB2  1 
ATOM   1053  H  HB3  . GLU   A 1 68  ? 3.008   11.442  12.187  1.00 56.10  ?  67  GLU   B HB3  1 
ATOM   1054  H  HG2  . GLU   A 1 68  ? 1.201   12.285  11.062  1.00 71.76  ?  67  GLU   B HG2  1 
ATOM   1055  H  HG3  . GLU   A 1 68  ? 2.055   13.487  10.468  1.00 71.76  ?  67  GLU   B HG3  1 
ATOM   1056  N  N    . ALA   A 1 69  ? 5.143   13.400  14.165  1.00 48.71  ?  68  ALA   B N    1 
ATOM   1057  C  CA   . ALA   A 1 69  ? 6.000   13.012  15.292  1.00 45.88  ?  68  ALA   B CA   1 
ATOM   1058  C  C    . ALA   A 1 69  ? 5.652   13.804  16.558  1.00 36.00  ?  68  ALA   B C    1 
ATOM   1059  O  O    . ALA   A 1 69  ? 5.523   13.244  17.645  1.00 33.97  ?  68  ALA   B O    1 
ATOM   1060  C  CB   . ALA   A 1 69  ? 7.479   13.220  14.937  1.00 40.89  ?  68  ALA   B CB   1 
ATOM   1061  H  H    . ALA   A 1 69  ? 5.540   13.858  13.555  1.00 58.45  ?  68  ALA   B H    1 
ATOM   1062  H  HA   . ALA   A 1 69  ? 5.855   12.069  15.469  1.00 55.05  ?  68  ALA   B HA   1 
ATOM   1063  H  HB1  . ALA   A 1 69  ? 8.026   12.951  15.692  1.00 49.07  ?  68  ALA   B HB1  1 
ATOM   1064  H  HB2  . ALA   A 1 69  ? 7.697   12.680  14.162  1.00 49.07  ?  68  ALA   B HB2  1 
ATOM   1065  H  HB3  . ALA   A 1 69  ? 7.627   14.158  14.739  1.00 49.07  ?  68  ALA   B HB3  1 
ATOM   1066  N  N    . PHE   A 1 70  ? 5.560   15.123  16.438  1.00 43.53  ?  69  PHE   B N    1 
ATOM   1067  C  CA   . PHE   A 1 70  ? 5.184   15.957  17.568  1.00 47.98  ?  69  PHE   B CA   1 
ATOM   1068  C  C    . PHE   A 1 70  ? 3.810   15.583  18.085  1.00 44.33  ?  69  PHE   B C    1 
ATOM   1069  O  O    . PHE   A 1 70  ? 3.577   15.585  19.293  1.00 48.23  ?  69  PHE   B O    1 
ATOM   1070  C  CB   . PHE   A 1 70  ? 5.215   17.420  17.146  1.00 45.29  ?  69  PHE   B CB   1 
ATOM   1071  C  CG   . PHE   A 1 70  ? 4.721   18.367  18.188  1.00 43.60  ?  69  PHE   B CG   1 
ATOM   1072  C  CD1  . PHE   A 1 70  ? 5.536   18.771  19.232  1.00 50.25  ?  69  PHE   B CD1  1 
ATOM   1073  C  CD2  . PHE   A 1 70  ? 3.435   18.846  18.141  1.00 49.03  ?  69  PHE   B CD2  1 
ATOM   1074  C  CE1  . PHE   A 1 70  ? 5.071   19.660  20.205  1.00 43.40  ?  69  PHE   B CE1  1 
ATOM   1075  C  CE2  . PHE   A 1 70  ? 2.976   19.721  19.107  1.00 49.64  ?  69  PHE   B CE2  1 
ATOM   1076  C  CZ   . PHE   A 1 70  ? 3.818   20.140  20.132  1.00 48.76  ?  69  PHE   B CZ   1 
ATOM   1077  H  H    . PHE   A 1 70  ? 5.710   15.560  15.712  1.00 52.24  ?  69  PHE   B H    1 
ATOM   1078  H  HA   . PHE   A 1 70  ? 5.820   15.830  18.289  1.00 57.57  ?  69  PHE   B HA   1 
ATOM   1079  H  HB2  . PHE   A 1 70  ? 6.131   17.664  16.938  1.00 54.35  ?  69  PHE   B HB2  1 
ATOM   1080  H  HB3  . PHE   A 1 70  ? 4.656   17.528  16.361  1.00 54.35  ?  69  PHE   B HB3  1 
ATOM   1081  H  HD1  . PHE   A 1 70  ? 6.406   18.446  19.287  1.00 60.30  ?  69  PHE   B HD1  1 
ATOM   1082  H  HD2  . PHE   A 1 70  ? 2.868   18.579  17.453  1.00 58.84  ?  69  PHE   B HD2  1 
ATOM   1083  H  HE1  . PHE   A 1 70  ? 5.628   19.919  20.903  1.00 52.08  ?  69  PHE   B HE1  1 
ATOM   1084  H  HE2  . PHE   A 1 70  ? 2.100   20.032  19.071  1.00 59.57  ?  69  PHE   B HE2  1 
ATOM   1085  H  HZ   . PHE   A 1 70  ? 3.515   20.750  20.764  1.00 58.51  ?  69  PHE   B HZ   1 
ATOM   1086  N  N    . GLU   A 1 71  ? 2.894   15.223  17.194  1.00 40.01  ?  70  GLU   B N    1 
ATOM   1087  C  CA   . GLU   A 1 71  ? 1.540   14.933  17.648  1.00 45.01  ?  70  GLU   B CA   1 
ATOM   1088  C  C    . GLU   A 1 71  ? 1.458   13.634  18.434  1.00 37.53  ?  70  GLU   B C    1 
ATOM   1089  O  O    . GLU   A 1 71  ? 0.580   13.496  19.286  1.00 38.61  ?  70  GLU   B O    1 
ATOM   1090  C  CB   . GLU   A 1 71  ? 0.575   14.868  16.467  1.00 42.06  ?  70  GLU   B CB   1 
ATOM   1091  C  CG   . GLU   A 1 71  ? 0.083   16.235  16.040  1.00 46.70  ?  70  GLU   B CG   1 
ATOM   1092  C  CD   . GLU   A 1 71  ? -0.917  16.188  14.906  1.00 59.48  ?  70  GLU   B CD   1 
ATOM   1093  O  OE1  . GLU   A 1 71  ? -1.230  15.084  14.399  1.00 57.27  ?  70  GLU   B OE1  1 
ATOM   1094  O  OE2  . GLU   A 1 71  ? -1.375  17.279  14.517  1.00 71.56  -1 70  GLU   B OE2  1 
ATOM   1095  H  H    . GLU   A 1 71  ? 3.026   15.142  16.348  1.00 48.02  ?  70  GLU   B H    1 
ATOM   1096  H  HA   . GLU   A 1 71  ? 1.268   15.661  18.229  1.00 54.01  ?  70  GLU   B HA   1 
ATOM   1097  H  HB2  . GLU   A 1 71  ? 1.027   14.462  15.711  1.00 50.47  ?  70  GLU   B HB2  1 
ATOM   1098  H  HB3  . GLU   A 1 71  ? -0.196  14.336  16.718  1.00 50.47  ?  70  GLU   B HB3  1 
ATOM   1099  H  HG2  . GLU   A 1 71  ? -0.346  16.664  16.797  1.00 56.04  ?  70  GLU   B HG2  1 
ATOM   1100  H  HG3  . GLU   A 1 71  ? 0.842   16.762  15.745  1.00 56.04  ?  70  GLU   B HG3  1 
ATOM   1101  N  N    . TYR   A 1 72  ? 2.321   12.667  18.142  1.00 33.53  ?  71  TYR   B N    1 
ATOM   1102  C  CA   . TYR   A 1 72  ? 2.354   11.385  18.830  1.00 33.45  ?  71  TYR   B CA   1 
ATOM   1103  C  C    . TYR   A 1 72  ? 3.232   11.433  20.089  1.00 40.81  ?  71  TYR   B C    1 
ATOM   1104  O  O    . TYR   A 1 72  ? 2.893   10.806  21.105  1.00 38.45  ?  71  TYR   B O    1 
ATOM   1105  C  CB   . TYR   A 1 72  ? 2.869   10.311  17.861  1.00 34.55  ?  71  TYR   B CB   1 
ATOM   1106  C  CG   . TYR   A 1 72  ? 2.595   8.867   18.259  1.00 36.02  ?  71  TYR   B CG   1 
ATOM   1107  C  CD1  . TYR   A 1 72  ? 1.294   8.404   18.380  1.00 40.11  ?  71  TYR   B CD1  1 
ATOM   1108  C  CD2  . TYR   A 1 72  ? 3.640   7.942   18.452  1.00 35.53  ?  71  TYR   B CD2  1 
ATOM   1109  C  CE1  . TYR   A 1 72  ? 1.020   7.103   18.705  1.00 32.86  ?  71  TYR   B CE1  1 
ATOM   1110  C  CE2  . TYR   A 1 72  ? 3.361   6.623   18.787  1.00 32.62  ?  71  TYR   B CE2  1 
ATOM   1111  C  CZ   . TYR   A 1 72  ? 2.030   6.226   18.926  1.00 34.72  ?  71  TYR   B CZ   1 
ATOM   1112  O  OH   . TYR   A 1 72  ? 1.682   4.934   19.275  1.00 38.10  ?  71  TYR   B OH   1 
ATOM   1113  H  H    . TYR   A 1 72  ? 2.919   12.733  17.528  1.00 40.23  ?  71  TYR   B H    1 
ATOM   1114  H  HA   . TYR   A 1 72  ? 1.458   11.136  19.108  1.00 40.14  ?  71  TYR   B HA   1 
ATOM   1115  H  HB2  . TYR   A 1 72  ? 2.449   10.455  16.998  1.00 41.46  ?  71  TYR   B HB2  1 
ATOM   1116  H  HB3  . TYR   A 1 72  ? 3.830   10.410  17.782  1.00 41.46  ?  71  TYR   B HB3  1 
ATOM   1117  H  HD1  . TYR   A 1 72  ? 0.589   8.993   18.237  1.00 48.13  ?  71  TYR   B HD1  1 
ATOM   1118  H  HD2  . TYR   A 1 72  ? 4.523   8.217   18.355  1.00 42.64  ?  71  TYR   B HD2  1 
ATOM   1119  H  HE1  . TYR   A 1 72  ? 0.137   6.820   18.775  1.00 39.43  ?  71  TYR   B HE1  1 
ATOM   1120  H  HE2  . TYR   A 1 72  ? 4.051   6.013   18.917  1.00 39.15  ?  71  TYR   B HE2  1 
ATOM   1121  H  HH   . TYR   A 1 72  ? 0.850   4.878   19.377  1.00 45.72  ?  71  TYR   B HH   1 
ATOM   1122  N  N    . TYR   A 1 73  ? 4.372   12.150  20.055  1.00 36.91  ?  72  TYR   B N    1 
ATOM   1123  C  CA   . TYR   A 1 73  ? 5.310   12.121  21.193  1.00 42.39  ?  72  TYR   B CA   1 
ATOM   1124  C  C    . TYR   A 1 73  ? 5.295   13.388  22.046  1.00 41.30  ?  72  TYR   B C    1 
ATOM   1125  O  O    . TYR   A 1 73  ? 5.783   13.362  23.185  1.00 40.40  ?  72  TYR   B O    1 
ATOM   1126  C  CB   . TYR   A 1 73  ? 6.759   11.900  20.719  1.00 30.98  ?  72  TYR   B CB   1 
ATOM   1127  C  CG   . TYR   A 1 73  ? 6.935   10.621  19.974  1.00 36.16  ?  72  TYR   B CG   1 
ATOM   1128  C  CD1  . TYR   A 1 73  ? 6.826   9.407   20.634  1.00 30.15  ?  72  TYR   B CD1  1 
ATOM   1129  C  CD2  . TYR   A 1 73  ? 7.209   10.617  18.585  1.00 34.57  ?  72  TYR   B CD2  1 
ATOM   1130  C  CE1  . TYR   A 1 73  ? 6.999   8.210   19.956  1.00 28.40  ?  72  TYR   B CE1  1 
ATOM   1131  C  CE2  . TYR   A 1 73  ? 7.359   9.417   17.890  1.00 29.91  ?  72  TYR   B CE2  1 
ATOM   1132  C  CZ   . TYR   A 1 73  ? 7.240   8.214   18.577  1.00 34.07  ?  72  TYR   B CZ   1 
ATOM   1133  O  OH   . TYR   A 1 73  ? 7.372   7.013   17.890  1.00 34.35  ?  72  TYR   B OH   1 
ATOM   1134  H  H    . TYR   A 1 73  ? 4.618   12.649  19.400  1.00 44.30  ?  72  TYR   B H    1 
ATOM   1135  H  HA   . TYR   A 1 73  ? 5.050   11.370  21.750  1.00 50.87  ?  72  TYR   B HA   1 
ATOM   1136  H  HB2  . TYR   A 1 73  ? 7.012   12.628  20.130  1.00 37.18  ?  72  TYR   B HB2  1 
ATOM   1137  H  HB3  . TYR   A 1 73  ? 7.344   11.880  21.492  1.00 37.18  ?  72  TYR   B HB3  1 
ATOM   1138  H  HD1  . TYR   A 1 73  ? 6.634   9.395   21.543  1.00 36.18  ?  72  TYR   B HD1  1 
ATOM   1139  H  HD2  . TYR   A 1 73  ? 7.289   11.424  18.130  1.00 41.49  ?  72  TYR   B HD2  1 
ATOM   1140  H  HE1  . TYR   A 1 73  ? 6.955   7.404   20.418  1.00 34.08  ?  72  TYR   B HE1  1 
ATOM   1141  H  HE2  . TYR   A 1 73  ? 7.538   9.421   16.978  1.00 35.89  ?  72  TYR   B HE2  1 
ATOM   1142  H  HH   . TYR   A 1 73  ? 7.597   7.160   17.095  1.00 41.22  ?  72  TYR   B HH   1 
ATOM   1143  N  N    . HIS   A 1 74  ? 4.769   14.495  21.524  1.00 41.50  ?  73  HIS   B N    1 
ATOM   1144  C  CA   . HIS   A 1 74  ? 4.724   15.754  22.256  1.00 39.92  ?  73  HIS   B CA   1 
ATOM   1145  C  C    . HIS   A 1 74  ? 6.136   16.205  22.559  1.00 47.78  ?  73  HIS   B C    1 
ATOM   1146  O  O    . HIS   A 1 74  ? 6.463   16.594  23.677  1.00 47.96  ?  73  HIS   B O    1 
ATOM   1147  C  CB   . HIS   A 1 74  ? 3.899   15.637  23.534  1.00 43.64  ?  73  HIS   B CB   1 
ATOM   1148  C  CG   . HIS   A 1 74  ? 2.425   15.559  23.288  1.00 50.74  ?  73  HIS   B CG   1 
ATOM   1149  N  ND1  . HIS   A 1 74  ? 1.486   15.658  24.300  1.00 43.08  ?  73  HIS   B ND1  1 
ATOM   1150  C  CD2  . HIS   A 1 74  ? 1.728   15.386  22.136  1.00 47.70  ?  73  HIS   B CD2  1 
ATOM   1151  C  CE1  . HIS   A 1 74  ? 0.278   15.553  23.777  1.00 47.72  ?  73  HIS   B CE1  1 
ATOM   1152  N  NE2  . HIS   A 1 74  ? 0.396   15.373  22.469  1.00 46.64  ?  73  HIS   B NE2  1 
ATOM   1153  H  H    . HIS   A 1 74  ? 4.427   14.540  20.736  1.00 49.80  ?  73  HIS   B H    1 
ATOM   1154  H  HA   . HIS   A 1 74  ? 4.291   16.428  21.709  1.00 47.91  ?  73  HIS   B HA   1 
ATOM   1155  H  HB2  . HIS   A 1 74  ? 4.164   14.831  24.005  1.00 52.36  ?  73  HIS   B HB2  1 
ATOM   1156  H  HB3  . HIS   A 1 74  ? 4.067   16.415  24.088  1.00 52.36  ?  73  HIS   B HB3  1 
ATOM   1157  H  HD2  . HIS   A 1 74  ? 2.086   15.294  21.283  1.00 57.24  ?  73  HIS   B HD2  1 
ATOM   1158  H  HE1  . HIS   A 1 74  ? -0.523  15.598  24.248  1.00 57.26  ?  73  HIS   B HE1  1 
ATOM   1159  H  HE2  . HIS   A 1 74  ? -0.256  15.266  21.918  1.00 55.96  ?  73  HIS   B HE2  1 
ATOM   1160  N  N    . THR   A 1 75  ? 6.997   16.104  21.558  1.00 43.78  ?  74  THR   B N    1 
ATOM   1161  C  CA   . THR   A 1 75  ? 8.337   16.632  21.690  1.00 43.48  ?  74  THR   B CA   1 
ATOM   1162  C  C    . THR   A 1 75  ? 8.835   16.924  20.287  1.00 48.59  ?  74  THR   B C    1 
ATOM   1163  O  O    . THR   A 1 75  ? 8.530   16.181  19.352  1.00 50.11  ?  74  THR   B O    1 
ATOM   1164  C  CB   . THR   A 1 75  ? 9.242   15.641  22.454  1.00 48.68  ?  74  THR   B CB   1 
ATOM   1165  O  OG1  . THR   A 1 75  ? 10.557  16.207  22.651  1.00 50.61  ?  74  THR   B OG1  1 
ATOM   1166  C  CG2  . THR   A 1 75  ? 9.327   14.309  21.716  1.00 45.45  ?  74  THR   B CG2  1 
ATOM   1167  H  H    . THR   A 1 75  ? 6.828   15.735  20.800  1.00 52.54  ?  74  THR   B H    1 
ATOM   1168  H  HA   . THR   A 1 75  ? 8.356   17.463  22.190  1.00 52.18  ?  74  THR   B HA   1 
ATOM   1169  H  HB   . THR   A 1 75  ? 8.860   15.465  23.328  1.00 58.41  ?  74  THR   B HB   1 
ATOM   1170  H  HG1  . THR   A 1 75  ? 11.061  15.642  23.014  1.00 60.73  ?  74  THR   B HG1  1 
ATOM   1171  H  HG21 . THR   A 1 75  ? 9.771   13.650  22.272  1.00 54.54  ?  74  THR   B HG21 1 
ATOM   1172  H  HG22 . THR   A 1 75  ? 8.435   13.991  21.503  1.00 54.54  ?  74  THR   B HG22 1 
ATOM   1173  H  HG23 . THR   A 1 75  ? 9.828   14.416  20.893  1.00 54.54  ?  74  THR   B HG23 1 
ATOM   1174  N  N    . THR   A 1 76  ? 9.591   18.013  20.153  1.00 52.12  ?  75  THR   B N    1 
ATOM   1175  C  CA   . THR   A 1 76  ? 10.296  18.359  18.924  1.00 50.69  ?  75  THR   B CA   1 
ATOM   1176  C  C    . THR   A 1 76  ? 11.780  18.027  18.979  1.00 51.51  ?  75  THR   B C    1 
ATOM   1177  O  O    . THR   A 1 76  ? 12.500  18.322  18.015  1.00 61.56  ?  75  THR   B O    1 
ATOM   1178  C  CB   . THR   A 1 76  ? 10.124  19.851  18.634  1.00 50.60  ?  75  THR   B CB   1 
ATOM   1179  O  OG1  . THR   A 1 76  ? 10.434  20.597  19.824  1.00 56.56  ?  75  THR   B OG1  1 
ATOM   1180  C  CG2  . THR   A 1 76  ? 8.712   20.139  18.205  1.00 52.15  ?  75  THR   B CG2  1 
ATOM   1181  H  H    . THR   A 1 76  ? 9.713   18.586  20.783  1.00 62.54  ?  75  THR   B H    1 
ATOM   1182  H  HA   . THR   A 1 76  ? 9.906   17.856  18.191  1.00 60.83  ?  75  THR   B HA   1 
ATOM   1183  H  HB   . THR   A 1 76  ? 10.718  20.125  17.917  1.00 60.72  ?  75  THR   B HB   1 
ATOM   1184  H  HG1  . THR   A 1 76  ? 10.209  21.400  19.727  1.00 67.87  ?  75  THR   B HG1  1 
ATOM   1185  H  HG21 . THR   A 1 76  ? 8.589   21.094  18.087  1.00 62.58  ?  75  THR   B HG21 1 
ATOM   1186  H  HG22 . THR   A 1 76  ? 8.523   19.692  17.365  1.00 62.58  ?  75  THR   B HG22 1 
ATOM   1187  H  HG23 . THR   A 1 76  ? 8.090   19.822  18.878  1.00 62.58  ?  75  THR   B HG23 1 
ATOM   1188  N  N    . ASP   A 1 77  ? 12.260  17.415  20.067  1.00 44.11  ?  76  ASP   B N    1 
ATOM   1189  C  CA   . ASP   A 1 77  ? 13.676  17.035  20.191  1.00 46.46  ?  76  ASP   B CA   1 
ATOM   1190  C  C    . ASP   A 1 77  ? 14.169  16.128  19.072  1.00 51.83  ?  76  ASP   B C    1 
ATOM   1191  O  O    . ASP   A 1 77  ? 13.802  14.942  19.031  1.00 51.28  ?  76  ASP   B O    1 
ATOM   1192  C  CB   . ASP   A 1 77  ? 13.874  16.338  21.544  1.00 51.54  ?  76  ASP   B CB   1 
ATOM   1193  C  CG   . ASP   A 1 77  ? 15.310  15.940  21.828  1.00 49.81  ?  76  ASP   B CG   1 
ATOM   1194  O  OD1  . ASP   A 1 77  ? 16.183  16.097  20.944  1.00 53.32  ?  76  ASP   B OD1  1 
ATOM   1195  O  OD2  . ASP   A 1 77  ? 15.542  15.463  22.974  1.00 54.42  -1 76  ASP   B OD2  1 
ATOM   1196  H  H    . ASP   A 1 77  ? 11.784  17.207  20.753  1.00 52.93  ?  76  ASP   B H    1 
ATOM   1197  H  HA   . ASP   A 1 77  ? 14.208  17.843  20.122  1.00 55.76  ?  76  ASP   B HA   1 
ATOM   1198  H  HB2  . ASP   A 1 77  ? 13.590  16.940  22.249  1.00 61.85  ?  76  ASP   B HB2  1 
ATOM   1199  H  HB3  . ASP   A 1 77  ? 13.336  15.531  21.560  1.00 61.85  ?  76  ASP   B HB3  1 
ATOM   1200  N  N    . PRO   A 1 78  ? 15.051  16.621  18.195  1.00 48.53  ?  77  PRO   B N    1 
ATOM   1201  C  CA   . PRO   A 1 78  ? 15.401  15.825  17.006  1.00 47.69  ?  77  PRO   B CA   1 
ATOM   1202  C  C    . PRO   A 1 78  ? 16.021  14.474  17.319  1.00 46.35  ?  77  PRO   B C    1 
ATOM   1203  O  O    . PRO   A 1 78  ? 15.946  13.558  16.482  1.00 48.07  ?  77  PRO   B O    1 
ATOM   1204  C  CB   . PRO   A 1 78  ? 16.389  16.720  16.239  1.00 46.88  ?  77  PRO   B CB   1 
ATOM   1205  C  CG   . PRO   A 1 78  ? 16.362  18.065  16.916  1.00 54.40  ?  77  PRO   B CG   1 
ATOM   1206  C  CD   . PRO   A 1 78  ? 15.852  17.854  18.313  1.00 51.69  ?  77  PRO   B CD   1 
ATOM   1207  H  HA   . PRO   A 1 78  ? 14.601  15.696  16.473  1.00 57.22  ?  77  PRO   B HA   1 
ATOM   1208  H  HB2  . PRO   A 1 78  ? 17.277  16.333  16.282  1.00 56.25  ?  77  PRO   B HB2  1 
ATOM   1209  H  HB3  . PRO   A 1 78  ? 16.105  16.797  15.314  1.00 56.25  ?  77  PRO   B HB3  1 
ATOM   1210  H  HG2  . PRO   A 1 78  ? 17.260  18.432  16.936  1.00 65.28  ?  77  PRO   B HG2  1 
ATOM   1211  H  HG3  . PRO   A 1 78  ? 15.772  18.659  16.427  1.00 65.28  ?  77  PRO   B HG3  1 
ATOM   1212  H  HD2  . PRO   A 1 78  ? 16.587  17.731  18.934  1.00 62.03  ?  77  PRO   B HD2  1 
ATOM   1213  H  HD3  . PRO   A 1 78  ? 15.300  18.600  18.595  1.00 62.03  ?  77  PRO   B HD3  1 
ATOM   1214  N  N    . SER   A 1 79  ? 16.649  14.315  18.483  1.00 44.33  ?  78  SER   B N    1 
ATOM   1215  C  CA   . SER   A 1 79  ? 17.296  13.045  18.817  1.00 48.16  ?  78  SER   B CA   1 
ATOM   1216  C  C    . SER   A 1 79  ? 16.353  12.021  19.442  1.00 46.58  ?  78  SER   B C    1 
ATOM   1217  O  O    . SER   A 1 79  ? 16.775  10.895  19.736  1.00 44.48  ?  78  SER   B O    1 
ATOM   1218  C  CB   . SER   A 1 79  ? 18.421  13.264  19.818  1.00 44.99  ?  78  SER   B CB   1 
ATOM   1219  O  OG   . SER   A 1 79  ? 17.820  13.680  21.046  1.00 39.12  ?  78  SER   B OG   1 
ATOM   1220  H  H    . SER   A 1 79  ? 16.715  14.921  19.089  1.00 53.20  ?  78  SER   B H    1 
ATOM   1221  H  HA   . SER   A 1 79  ? 17.656  12.687  17.990  1.00 57.79  ?  78  SER   B HA   1 
ATOM   1222  H  HB2  . SER   A 1 79  ? 18.909  12.436  19.952  1.00 53.99  ?  78  SER   B HB2  1 
ATOM   1223  H  HB3  . SER   A 1 79  ? 19.021  13.954  19.494  1.00 53.99  ?  78  SER   B HB3  1 
ATOM   1224  H  HG   . SER   A 1 79  ? 18.382  13.640  21.669  1.00 46.94  ?  78  SER   B HG   1 
ATOM   1225  N  N    . PHE   A 1 80  ? 15.112  12.403  19.725  1.00 45.29  ?  79  PHE   B N    1 
ATOM   1226  C  CA   . PHE   A 1 80  ? 14.253  11.564  20.559  1.00 45.35  ?  79  PHE   B CA   1 
ATOM   1227  C  C    . PHE   A 1 80  ? 13.994  10.202  19.912  1.00 47.75  ?  79  PHE   B C    1 
ATOM   1228  O  O    . PHE   A 1 80  ? 14.047  9.160   20.588  1.00 42.20  ?  79  PHE   B O    1 
ATOM   1229  C  CB   . PHE   A 1 80  ? 12.934  12.295  20.846  1.00 48.73  ?  79  PHE   B CB   1 
ATOM   1230  C  CG   . PHE   A 1 80  ? 11.949  11.482  21.628  1.00 44.05  ?  79  PHE   B CG   1 
ATOM   1231  C  CD1  . PHE   A 1 80  ? 11.098  10.603  20.991  1.00 42.76  ?  79  PHE   B CD1  1 
ATOM   1232  C  CD2  . PHE   A 1 80  ? 11.875  11.598  23.002  1.00 47.06  ?  79  PHE   B CD2  1 
ATOM   1233  C  CE1  . PHE   A 1 80  ? 10.182  9.857   21.707  1.00 42.51  ?  79  PHE   B CE1  1 
ATOM   1234  C  CE2  . PHE   A 1 80  ? 10.935  10.840  23.744  1.00 41.86  ?  79  PHE   B CE2  1 
ATOM   1235  C  CZ   . PHE   A 1 80  ? 10.106  9.979   23.094  1.00 36.63  ?  79  PHE   B CZ   1 
ATOM   1236  H  H    . PHE   A 1 80  ? 14.746  13.132  19.452  1.00 54.35  ?  79  PHE   B H    1 
ATOM   1237  H  HA   . PHE   A 1 80  ? 14.703  11.403  21.404  1.00 54.42  ?  79  PHE   B HA   1 
ATOM   1238  H  HB2  . PHE   A 1 80  ? 13.127  13.097  21.356  1.00 58.47  ?  79  PHE   B HB2  1 
ATOM   1239  H  HB3  . PHE   A 1 80  ? 12.519  12.530  20.002  1.00 58.47  ?  79  PHE   B HB3  1 
ATOM   1240  H  HD1  . PHE   A 1 80  ? 11.141  10.511  20.066  1.00 51.31  ?  79  PHE   B HD1  1 
ATOM   1241  H  HD2  . PHE   A 1 80  ? 12.449  12.181  23.446  1.00 56.47  ?  79  PHE   B HD2  1 
ATOM   1242  H  HE1  . PHE   A 1 80  ? 9.613   9.271   21.262  1.00 51.02  ?  79  PHE   B HE1  1 
ATOM   1243  H  HE2  . PHE   A 1 80  ? 10.885  10.931  24.669  1.00 50.23  ?  79  PHE   B HE2  1 
ATOM   1244  H  HZ   . PHE   A 1 80  ? 9.490   9.473   23.574  1.00 43.95  ?  79  PHE   B HZ   1 
ATOM   1245  N  N    . LEU   A 1 81  ? 13.681  10.195  18.607  1.00 47.76  ?  80  LEU   B N    1 
ATOM   1246  C  CA   . LEU   A 1 81  ? 13.394  8.936   17.919  1.00 47.54  ?  80  LEU   B CA   1 
ATOM   1247  C  C    . LEU   A 1 81  ? 14.591  7.987   17.978  1.00 46.98  ?  80  LEU   B C    1 
ATOM   1248  O  O    . LEU   A 1 81  ? 14.437  6.794   18.272  1.00 46.83  ?  80  LEU   B O    1 
ATOM   1249  C  CB   . LEU   A 1 81  ? 13.021  9.181   16.454  1.00 48.75  ?  80  LEU   B CB   1 
ATOM   1250  C  CG   . LEU   A 1 81  ? 11.568  9.056   15.985  1.00 51.27  ?  80  LEU   B CG   1 
ATOM   1251  C  CD1  . LEU   A 1 81  ? 11.085  7.645   15.942  1.00 36.63  ?  80  LEU   B CD1  1 
ATOM   1252  C  CD2  . LEU   A 1 81  ? 10.714  9.908   16.921  1.00 56.83  ?  80  LEU   B CD2  1 
ATOM   1253  H  H    . LEU   A 1 81  ? 13.629  10.894  18.109  1.00 57.31  ?  80  LEU   B H    1 
ATOM   1254  H  HA   . LEU   A 1 81  ? 12.636  8.527   18.365  1.00 57.05  ?  80  LEU   B HA   1 
ATOM   1255  H  HB2  . LEU   A 1 81  ? 13.294  10.086  16.239  1.00 58.50  ?  80  LEU   B HB2  1 
ATOM   1256  H  HB3  . LEU   A 1 81  ? 13.528  8.547   15.922  1.00 58.50  ?  80  LEU   B HB3  1 
ATOM   1257  H  HG   . LEU   A 1 81  ? 11.491  9.370   15.070  1.00 61.52  ?  80  LEU   B HG   1 
ATOM   1258  H  HD11 . LEU   A 1 81  ? 10.164  7.636   15.639  1.00 43.96  ?  80  LEU   B HD11 1 
ATOM   1259  H  HD12 . LEU   A 1 81  ? 11.640  7.140   15.328  1.00 43.96  ?  80  LEU   B HD12 1 
ATOM   1260  H  HD13 . LEU   A 1 81  ? 11.144  7.264   16.832  1.00 43.96  ?  80  LEU   B HD13 1 
ATOM   1261  H  HD21 . LEU   A 1 81  ? 9.786   9.847   16.645  1.00 68.20  ?  80  LEU   B HD21 1 
ATOM   1262  H  HD22 . LEU   A 1 81  ? 10.812  9.576   17.827  1.00 68.20  ?  80  LEU   B HD22 1 
ATOM   1263  H  HD23 . LEU   A 1 81  ? 11.014  10.829  16.871  1.00 68.20  ?  80  LEU   B HD23 1 
ATOM   1264  N  N    . GLY   A 1 82  ? 15.787  8.486   17.647  1.00 38.70  ?  81  GLY   B N    1 
ATOM   1265  C  CA   . GLY   A 1 82  ? 16.973  7.640   17.747  1.00 45.88  ?  81  GLY   B CA   1 
ATOM   1266  C  C    . GLY   A 1 82  ? 17.160  7.026   19.133  1.00 43.17  ?  81  GLY   B C    1 
ATOM   1267  O  O    . GLY   A 1 82  ? 17.399  5.820   19.279  1.00 39.94  ?  81  GLY   B O    1 
ATOM   1268  H  H    . GLY   A 1 82  ? 15.932  9.287   17.369  1.00 46.44  ?  81  GLY   B H    1 
ATOM   1269  H  HA2  . GLY   A 1 82  ? 16.904  6.918   17.103  1.00 55.05  ?  81  GLY   B HA2  1 
ATOM   1270  H  HA3  . GLY   A 1 82  ? 17.759  8.171   17.544  1.00 55.05  ?  81  GLY   B HA3  1 
ATOM   1271  N  N    . ARG   A 1 83  ? 17.054  7.842   20.179  1.00 41.61  ?  82  ARG   B N    1 
ATOM   1272  C  CA   . ARG   A 1 83  ? 17.236  7.287   21.524  1.00 45.22  ?  82  ARG   B CA   1 
ATOM   1273  C  C    . ARG   A 1 83  ? 16.147  6.270   21.819  1.00 37.58  ?  82  ARG   B C    1 
ATOM   1274  O  O    . ARG   A 1 83  ? 16.421  5.204   22.377  1.00 38.01  ?  82  ARG   B O    1 
ATOM   1275  C  CB   . ARG   A 1 83  ? 17.259  8.390   22.582  1.00 37.94  ?  82  ARG   B CB   1 
ATOM   1276  C  CG   . ARG   A 1 83  ? 18.317  9.449   22.296  1.00 45.70  ?  82  ARG   B CG   1 
ATOM   1277  C  CD   . ARG   A 1 83  ? 18.425  10.444  23.435  1.00 42.99  ?  82  ARG   B CD   1 
ATOM   1278  N  NE   . ARG   A 1 83  ? 17.512  11.572  23.274  1.00 43.78  ?  82  ARG   B NE   1 
ATOM   1279  C  CZ   . ARG   A 1 83  ? 16.399  11.720  23.979  1.00 42.88  ?  82  ARG   B CZ   1 
ATOM   1280  N  NH1  . ARG   A 1 83  ? 16.003  10.797  24.837  1.00 38.93  ?  82  ARG   B NH1  1 
ATOM   1281  N  NH2  . ARG   A 1 83  ? 15.700  12.841  23.862  1.00 37.64  ?  82  ARG   B NH2  1 
ATOM   1282  H  H    . ARG   A 1 83  ? 16.885  8.685   20.143  1.00 49.93  ?  82  ARG   B H    1 
ATOM   1283  H  HA   . ARG   A 1 83  ? 18.099  6.846   21.568  1.00 54.26  ?  82  ARG   B HA   1 
ATOM   1284  H  HB2  . ARG   A 1 83  ? 16.393  8.826   22.603  1.00 45.53  ?  82  ARG   B HB2  1 
ATOM   1285  H  HB3  . ARG   A 1 83  ? 17.453  7.995   23.447  1.00 45.53  ?  82  ARG   B HB3  1 
ATOM   1286  H  HG2  . ARG   A 1 83  ? 19.180  9.019   22.182  1.00 54.84  ?  82  ARG   B HG2  1 
ATOM   1287  H  HG3  . ARG   A 1 83  ? 18.079  9.932   21.489  1.00 54.84  ?  82  ARG   B HG3  1 
ATOM   1288  H  HD2  . ARG   A 1 83  ? 18.209  9.997   24.269  1.00 51.59  ?  82  ARG   B HD2  1 
ATOM   1289  H  HD3  . ARG   A 1 83  ? 19.330  10.791  23.470  1.00 51.59  ?  82  ARG   B HD3  1 
ATOM   1290  H  HE   . ARG   A 1 83  ? 17.706  12.173  22.691  1.00 52.53  ?  82  ARG   B HE   1 
ATOM   1291  H  HH11 . ARG   A 1 83  ? 16.470  10.083  24.947  1.00 46.72  ?  82  ARG   B HH11 1 
ATOM   1292  H  HH12 . ARG   A 1 83  ? 15.278  10.910  25.286  1.00 46.72  ?  82  ARG   B HH12 1 
ATOM   1293  H  HH21 . ARG   A 1 83  ? 15.970  13.463  23.333  1.00 45.17  ?  82  ARG   B HH21 1 
ATOM   1294  H  HH22 . ARG   A 1 83  ? 14.976  12.946  24.315  1.00 45.17  ?  82  ARG   B HH22 1 
ATOM   1295  N  N    . TYR   A 1 84  ? 14.915  6.544   21.390  1.00 34.20  ?  83  TYR   B N    1 
ATOM   1296  C  CA   . TYR   A 1 84  ? 13.831  5.588   21.645  1.00 38.85  ?  83  TYR   B CA   1 
ATOM   1297  C  C    . TYR   A 1 84  ? 14.104  4.256   20.946  1.00 32.83  ?  83  TYR   B C    1 
ATOM   1298  O  O    . TYR   A 1 84  ? 13.934  3.171   21.536  1.00 35.40  ?  83  TYR   B O    1 
ATOM   1299  C  CB   . TYR   A 1 84  ? 12.494  6.202   21.217  1.00 34.64  ?  83  TYR   B CB   1 
ATOM   1300  C  CG   . TYR   A 1 84  ? 11.315  5.271   21.109  1.00 31.92  ?  83  TYR   B CG   1 
ATOM   1301  C  CD1  . TYR   A 1 84  ? 11.112  4.241   21.999  1.00 31.39  ?  83  TYR   B CD1  1 
ATOM   1302  C  CD2  . TYR   A 1 84  ? 10.381  5.463   20.129  1.00 40.85  ?  83  TYR   B CD2  1 
ATOM   1303  C  CE1  . TYR   A 1 84  ? 10.002  3.407   21.905  1.00 40.69  ?  83  TYR   B CE1  1 
ATOM   1304  C  CE2  . TYR   A 1 84  ? 9.256   4.632   20.003  1.00 40.19  ?  83  TYR   B CE2  1 
ATOM   1305  C  CZ   . TYR   A 1 84  ? 9.072   3.606   20.887  1.00 37.80  ?  83  TYR   B CZ   1 
ATOM   1306  O  OH   . TYR   A 1 84  ? 7.965   2.795   20.724  1.00 33.27  ?  83  TYR   B OH   1 
ATOM   1307  H  H    . TYR   A 1 84  ? 14.684  7.253   20.962  1.00 41.04  ?  83  TYR   B H    1 
ATOM   1308  H  HA   . TYR   A 1 84  ? 13.769  5.402   22.595  1.00 46.62  ?  83  TYR   B HA   1 
ATOM   1309  H  HB2  . TYR   A 1 84  ? 12.257  6.883   21.865  1.00 41.57  ?  83  TYR   B HB2  1 
ATOM   1310  H  HB3  . TYR   A 1 84  ? 12.617  6.604   20.343  1.00 41.57  ?  83  TYR   B HB3  1 
ATOM   1311  H  HD1  . TYR   A 1 84  ? 11.732  4.099   22.678  1.00 37.66  ?  83  TYR   B HD1  1 
ATOM   1312  H  HD2  . TYR   A 1 84  ? 10.494  6.164   19.529  1.00 49.02  ?  83  TYR   B HD2  1 
ATOM   1313  H  HE1  . TYR   A 1 84  ? 9.882   2.719   22.520  1.00 48.83  ?  83  TYR   B HE1  1 
ATOM   1314  H  HE2  . TYR   A 1 84  ? 8.639   4.779   19.322  1.00 48.22  ?  83  TYR   B HE2  1 
ATOM   1315  H  HH   . TYR   A 1 84  ? 7.746   2.456   21.460  1.00 39.93  ?  83  TYR   B HH   1 
ATOM   1316  N  N    . MET   A 1 85  ? 14.560  4.314   19.696  1.00 37.64  ?  84  MET   B N    1 
ATOM   1317  C  CA   . MET   A 1 85  ? 14.878  3.077   18.983  1.00 36.28  ?  84  MET   B CA   1 
ATOM   1318  C  C    . MET   A 1 85  ? 16.037  2.345   19.667  1.00 37.92  ?  84  MET   B C    1 
ATOM   1319  O  O    . MET   A 1 85  ? 15.925  1.146   19.961  1.00 34.89  ?  84  MET   B O    1 
ATOM   1320  C  CB   . MET   A 1 85  ? 15.188  3.380   17.511  1.00 41.60  ?  84  MET   B CB   1 
ATOM   1321  C  CG   . MET   A 1 85  ? 13.952  3.774   16.671  1.00 43.07  ?  84  MET   B CG   1 
ATOM   1322  S  SD   . MET   A 1 85  ? 12.745  2.385   16.556  1.00 47.45  ?  84  MET   B SD   1 
ATOM   1323  C  CE   . MET   A 1 85  ? 11.193  3.151   17.132  1.00 48.07  ?  84  MET   B CE   1 
ATOM   1324  H  H    . MET   A 1 85  ? 14.691  5.037   19.249  1.00 45.17  ?  84  MET   B H    1 
ATOM   1325  H  HA   . MET   A 1 85  ? 14.101  2.496   18.993  1.00 43.54  ?  84  MET   B HA   1 
ATOM   1326  H  HB2  . MET   A 1 85  ? 15.817  4.117   17.472  1.00 49.92  ?  84  MET   B HB2  1 
ATOM   1327  H  HB3  . MET   A 1 85  ? 15.579  2.589   17.107  1.00 49.92  ?  84  MET   B HB3  1 
ATOM   1328  H  HG2  . MET   A 1 85  ? 13.509  4.530   17.087  1.00 51.69  ?  84  MET   B HG2  1 
ATOM   1329  H  HG3  . MET   A 1 85  ? 14.235  4.008   15.773  1.00 51.69  ?  84  MET   B HG3  1 
ATOM   1330  H  HE1  . MET   A 1 85  ? 10.517  2.462   17.225  1.00 57.68  ?  84  MET   B HE1  1 
ATOM   1331  H  HE2  . MET   A 1 85  ? 11.351  3.578   17.988  1.00 57.68  ?  84  MET   B HE2  1 
ATOM   1332  H  HE3  . MET   A 1 85  ? 10.907  3.810   16.481  1.00 57.68  ?  84  MET   B HE3  1 
ATOM   1333  N  N    . SER   A 1 86  ? 17.153  3.051   19.950  1.00 31.41  ?  85  SER   B N    1 
ATOM   1334  C  CA   . SER   A 1 86  ? 18.269  2.397   20.640  1.00 37.15  ?  85  SER   B CA   1 
ATOM   1335  C  C    . SER   A 1 86  ? 17.799  1.744   21.941  1.00 37.63  ?  85  SER   B C    1 
ATOM   1336  O  O    . SER   A 1 86  ? 18.143  0.598   22.243  1.00 35.13  ?  85  SER   B O    1 
ATOM   1337  C  CB   . SER   A 1 86  ? 19.395  3.383   20.953  1.00 30.89  ?  85  SER   B CB   1 
ATOM   1338  O  OG   . SER   A 1 86  ? 19.495  4.348   19.949  1.00 45.79  ?  85  SER   B OG   1 
ATOM   1339  H  H    . SER   A 1 86  ? 17.279  3.879   19.757  1.00 37.69  ?  85  SER   B H    1 
ATOM   1340  H  HA   . SER   A 1 86  ? 18.623  1.722   20.040  1.00 44.58  ?  85  SER   B HA   1 
ATOM   1341  H  HB2  . SER   A 1 86  ? 19.206  3.823   21.797  1.00 37.07  ?  85  SER   B HB2  1 
ATOM   1342  H  HB3  . SER   A 1 86  ? 20.233  2.899   21.012  1.00 37.07  ?  85  SER   B HB3  1 
ATOM   1343  H  HG   . SER   A 1 86  ? 20.217  4.769   20.027  1.00 54.95  ?  85  SER   B HG   1 
ATOM   1344  N  N    . ALA   A 1 87  ? 17.011  2.456   22.737  1.00 34.66  ?  86  ALA   B N    1 
ATOM   1345  C  CA   . ALA   A 1 87  ? 16.495  1.826   23.951  1.00 33.61  ?  86  ALA   B CA   1 
ATOM   1346  C  C    . ALA   A 1 87  ? 15.658  0.592   23.608  1.00 37.97  ?  86  ALA   B C    1 
ATOM   1347  O  O    . ALA   A 1 87  ? 15.884  -0.492  24.164  1.00 29.39  ?  86  ALA   B O    1 
ATOM   1348  C  CB   . ALA   A 1 87  ? 15.672  2.833   24.754  1.00 35.45  ?  86  ALA   B CB   1 
ATOM   1349  H  H    . ALA   A 1 87  ? 16.768  3.270   22.606  1.00 41.59  ?  86  ALA   B H    1 
ATOM   1350  H  HA   . ALA   A 1 87  ? 17.241  1.543   24.502  1.00 40.34  ?  86  ALA   B HA   1 
ATOM   1351  H  HB1  . ALA   A 1 87  ? 15.323  2.396   25.546  1.00 42.54  ?  86  ALA   B HB1  1 
ATOM   1352  H  HB2  . ALA   A 1 87  ? 16.243  3.575   25.010  1.00 42.54  ?  86  ALA   B HB2  1 
ATOM   1353  H  HB3  . ALA   A 1 87  ? 14.940  3.154   24.204  1.00 42.54  ?  86  ALA   B HB3  1 
ATOM   1354  N  N    . LEU   A 1 88  ? 14.678  0.741   22.673  1.00 32.44  ?  87  LEU   B N    1 
ATOM   1355  C  CA   . LEU   A 1 88  ? 13.755  -0.352  22.358  1.00 27.01  ?  87  LEU   B CA   1 
ATOM   1356  C  C    . LEU   A 1 88  ? 14.493  -1.595  21.868  1.00 36.09  ?  87  LEU   B C    1 
ATOM   1357  O  O    . LEU   A 1 88  ? 14.057  -2.731  22.125  1.00 30.50  ?  87  LEU   B O    1 
ATOM   1358  C  CB   . LEU   A 1 88  ? 12.752  0.091   21.290  1.00 32.56  ?  87  LEU   B CB   1 
ATOM   1359  C  CG   . LEU   A 1 88  ? 11.770  -0.976  20.794  1.00 39.59  ?  87  LEU   B CG   1 
ATOM   1360  C  CD1  . LEU   A 1 88  ? 10.781  -1.349  21.904  1.00 45.10  ?  87  LEU   B CD1  1 
ATOM   1361  C  CD2  . LEU   A 1 88  ? 11.058  -0.510  19.527  1.00 39.52  ?  87  LEU   B CD2  1 
ATOM   1362  H  H    . LEU   A 1 88  ? 14.540  1.460   22.221  1.00 38.93  ?  87  LEU   B H    1 
ATOM   1363  H  HA   . LEU   A 1 88  ? 13.275  -0.576  23.170  1.00 32.41  ?  87  LEU   B HA   1 
ATOM   1364  H  HB2  . LEU   A 1 88  ? 12.224  0.818   21.657  1.00 39.07  ?  87  LEU   B HB2  1 
ATOM   1365  H  HB3  . LEU   A 1 88  ? 13.252  0.401   20.519  1.00 39.07  ?  87  LEU   B HB3  1 
ATOM   1366  H  HG   . LEU   A 1 88  ? 12.259  -1.780  20.561  1.00 47.51  ?  87  LEU   B HG   1 
ATOM   1367  H  HD11 . LEU   A 1 88  ? 10.216  -2.074  21.594  1.00 54.12  ?  87  LEU   B HD11 1 
ATOM   1368  H  HD12 . LEU   A 1 88  ? 11.278  -1.629  22.689  1.00 54.12  ?  87  LEU   B HD12 1 
ATOM   1369  H  HD13 . LEU   A 1 88  ? 10.237  -0.574  22.116  1.00 54.12  ?  87  LEU   B HD13 1 
ATOM   1370  H  HD21 . LEU   A 1 88  ? 10.399  -1.175  19.273  1.00 47.43  ?  87  LEU   B HD21 1 
ATOM   1371  H  HD22 . LEU   A 1 88  ? 10.622  0.338   19.704  1.00 47.43  ?  87  LEU   B HD22 1 
ATOM   1372  H  HD23 . LEU   A 1 88  ? 11.711  -0.405  18.818  1.00 47.43  ?  87  LEU   B HD23 1 
ATOM   1373  N  N    . ASN   A 1 89  ? 15.581  -1.393  21.101  1.00 34.65  ?  88  ASN   B N    1 
ATOM   1374  C  CA   . ASN   A 1 89  ? 16.457  -2.492  20.666  1.00 42.75  ?  88  ASN   B CA   1 
ATOM   1375  C  C    . ASN   A 1 89  ? 16.877  -3.391  21.837  1.00 41.48  ?  88  ASN   B C    1 
ATOM   1376  O  O    . ASN   A 1 89  ? 16.982  -4.615  21.697  1.00 42.98  ?  88  ASN   B O    1 
ATOM   1377  C  CB   . ASN   A 1 89  ? 17.673  -1.888  19.955  1.00 43.73  ?  88  ASN   B CB   1 
ATOM   1378  C  CG   . ASN   A 1 89  ? 18.503  -2.910  19.208  1.00 52.60  ?  88  ASN   B CG   1 
ATOM   1379  O  OD1  . ASN   A 1 89  ? 18.040  -3.974  18.802  1.00 49.95  ?  88  ASN   B OD1  1 
ATOM   1380  N  ND2  . ASN   A 1 89  ? 19.754  -2.558  18.995  1.00 53.89  ?  88  ASN   B ND2  1 
ATOM   1381  H  H    . ASN   A 1 89  ? 15.834  -0.622  20.818  1.00 41.58  ?  88  ASN   B H    1 
ATOM   1382  H  HA   . ASN   A 1 89  ? 15.984  -3.064  20.041  1.00 51.30  ?  88  ASN   B HA   1 
ATOM   1383  H  HB2  . ASN   A 1 89  ? 17.366  -1.228  19.314  1.00 52.48  ?  88  ASN   B HB2  1 
ATOM   1384  H  HB3  . ASN   A 1 89  ? 18.245  -1.467  20.616  1.00 52.48  ?  88  ASN   B HB3  1 
ATOM   1385  H  HD21 . ASN   A 1 89  ? 20.041  -1.797  19.275  1.00 64.67  ?  88  ASN   B HD21 1 
ATOM   1386  H  HD22 . ASN   A 1 89  ? 20.285  -3.089  18.576  1.00 64.67  ?  88  ASN   B HD22 1 
ATOM   1387  N  N    . HIS   A 1 90  ? 17.077  -2.807  23.012  1.00 40.20  ?  89  HIS   B N    1 
ATOM   1388  C  CA   . HIS   A 1 90  ? 17.363  -3.584  24.219  1.00 39.21  ?  89  HIS   B CA   1 
ATOM   1389  C  C    . HIS   A 1 90  ? 16.105  -4.083  24.945  1.00 37.20  ?  89  HIS   B C    1 
ATOM   1390  O  O    . HIS   A 1 90  ? 16.026  -5.273  25.288  1.00 32.81  ?  89  HIS   B O    1 
ATOM   1391  C  CB   . HIS   A 1 90  ? 18.202  -2.740  25.192  1.00 40.50  ?  89  HIS   B CB   1 
ATOM   1392  C  CG   . HIS   A 1 90  ? 19.609  -2.486  24.734  1.00 44.39  ?  89  HIS   B CG   1 
ATOM   1393  N  ND1  . HIS   A 1 90  ? 19.956  -1.378  23.989  1.00 49.61  ?  89  HIS   B ND1  1 
ATOM   1394  C  CD2  . HIS   A 1 90  ? 20.756  -3.172  24.941  1.00 42.71  ?  89  HIS   B CD2  1 
ATOM   1395  C  CE1  . HIS   A 1 90  ? 21.252  -1.400  23.739  1.00 47.86  ?  89  HIS   B CE1  1 
ATOM   1396  N  NE2  . HIS   A 1 90  ? 21.760  -2.483  24.300  1.00 48.88  ?  89  HIS   B NE2  1 
ATOM   1397  H  H    . HIS   A 1 90  ? 17.052  -1.958  23.142  1.00 48.24  ?  89  HIS   B H    1 
ATOM   1398  H  HA   . HIS   A 1 90  ? 17.868  -4.365  23.943  1.00 47.05  ?  89  HIS   B HA   1 
ATOM   1399  H  HB2  . HIS   A 1 90  ? 17.771  -1.879  25.308  1.00 48.60  ?  89  HIS   B HB2  1 
ATOM   1400  H  HB3  . HIS   A 1 90  ? 18.250  -3.204  26.043  1.00 48.60  ?  89  HIS   B HB3  1 
ATOM   1401  H  HD1  . HIS   A 1 90  ? 19.412  -0.766  23.728  1.00 59.53  ?  89  HIS   B HD1  1 
ATOM   1402  H  HD2  . HIS   A 1 90  ? 20.849  -3.961  25.425  1.00 51.25  ?  89  HIS   B HD2  1 
ATOM   1403  H  HE1  . HIS   A 1 90  ? 21.724  -0.765  23.252  1.00 57.43  ?  89  HIS   B HE1  1 
ATOM   1404  N  N    . THR   A 1 91  ? 15.121  -3.194  25.212  1.00 35.49  ?  90  THR   B N    1 
ATOM   1405  C  CA   . THR   A 1 91  ? 13.992  -3.594  26.062  1.00 42.91  ?  90  THR   B CA   1 
ATOM   1406  C  C    . THR   A 1 91  ? 13.116  -4.651  25.395  1.00 35.22  ?  90  THR   B C    1 
ATOM   1407  O  O    . THR   A 1 91  ? 12.384  -5.356  26.084  1.00 38.27  ?  90  THR   B O    1 
ATOM   1408  C  CB   . THR   A 1 91  ? 13.076  -2.422  26.453  1.00 39.15  ?  90  THR   B CB   1 
ATOM   1409  O  OG1  . THR   A 1 91  ? 12.383  -1.962  25.297  1.00 31.83  ?  90  THR   B OG1  1 
ATOM   1410  C  CG2  . THR   A 1 91  ? 13.859  -1.274  27.023  1.00 42.82  ?  90  THR   B CG2  1 
ATOM   1411  H  H    . THR   A 1 91  ? 15.091  -2.385  24.922  1.00 42.58  ?  90  THR   B H    1 
ATOM   1412  H  HA   . THR   A 1 91  ? 14.389  -3.937  26.877  1.00 51.50  ?  90  THR   B HA   1 
ATOM   1413  H  HB   . THR   A 1 91  ? 12.452  -2.729  27.130  1.00 46.98  ?  90  THR   B HB   1 
ATOM   1414  H  HG1  . THR   A 1 91  ? 12.015  -1.224  25.457  1.00 38.20  ?  90  THR   B HG1  1 
ATOM   1415  H  HG21 . THR   A 1 91  ? 13.257  -0.633  27.433  1.00 51.38  ?  90  THR   B HG21 1 
ATOM   1416  H  HG22 . THR   A 1 91  ? 14.480  -1.596  27.695  1.00 51.38  ?  90  THR   B HG22 1 
ATOM   1417  H  HG23 . THR   A 1 91  ? 14.359  -0.831  26.319  1.00 51.38  ?  90  THR   B HG23 1 
ATOM   1418  N  N    . LYS   A 1 92  ? 13.153  -4.771  24.067  1.00 34.95  ?  91  LYS   B N    1 
ATOM   1419  C  CA   . LYS   A 1 92  ? 12.391  -5.847  23.433  1.00 37.01  ?  91  LYS   B CA   1 
ATOM   1420  C  C    . LYS   A 1 92  ? 12.925  -7.222  23.817  1.00 35.74  ?  91  LYS   B C    1 
ATOM   1421  O  O    . LYS   A 1 92  ? 12.260  -8.230  23.577  1.00 36.67  ?  91  LYS   B O    1 
ATOM   1422  C  CB   . LYS   A 1 92  ? 12.396  -5.706  21.910  1.00 48.10  ?  91  LYS   B CB   1 
ATOM   1423  C  CG   . LYS   A 1 92  ? 13.768  -5.896  21.308  1.00 51.38  ?  91  LYS   B CG   1 
ATOM   1424  C  CD   . LYS   A 1 92  ? 13.763  -5.583  19.836  1.00 62.68  ?  91  LYS   B CD   1 
ATOM   1425  C  CE   . LYS   A 1 92  ? 14.943  -6.249  19.148  1.00 59.70  ?  91  LYS   B CE   1 
ATOM   1426  N  NZ   . LYS   A 1 92  ? 15.362  -5.455  17.942  1.00 66.98  ?  91  LYS   B NZ   1 
ATOM   1427  H  H    . LYS   A 1 92  ? 13.593  -4.263  23.531  1.00 41.94  ?  91  LYS   B H    1 
ATOM   1428  H  HA   . LYS   A 1 92  ? 11.469  -5.775  23.726  1.00 44.41  ?  91  LYS   B HA   1 
ATOM   1429  H  HB2  . LYS   A 1 92  ? 11.806  -6.375  21.530  1.00 57.72  ?  91  LYS   B HB2  1 
ATOM   1430  H  HB3  . LYS   A 1 92  ? 12.086  -4.817  21.675  1.00 57.72  ?  91  LYS   B HB3  1 
ATOM   1431  H  HG2  . LYS   A 1 92  ? 14.398  -5.301  21.745  1.00 61.65  ?  91  LYS   B HG2  1 
ATOM   1432  H  HG3  . LYS   A 1 92  ? 14.047  -6.817  21.424  1.00 61.65  ?  91  LYS   B HG3  1 
ATOM   1433  H  HD2  . LYS   A 1 92  ? 12.944  -5.914  19.436  1.00 75.21  ?  91  LYS   B HD2  1 
ATOM   1434  H  HD3  . LYS   A 1 92  ? 13.831  -4.624  19.707  1.00 75.21  ?  91  LYS   B HD3  1 
ATOM   1435  H  HE2  . LYS   A 1 92  ? 15.692  -6.299  19.762  1.00 71.64  ?  91  LYS   B HE2  1 
ATOM   1436  H  HE3  . LYS   A 1 92  ? 14.691  -7.140  18.860  1.00 71.64  ?  91  LYS   B HE3  1 
ATOM   1437  H  HZ1  . LYS   A 1 92  ? 16.182  -5.695  17.690  1.00 80.37  ?  91  LYS   B HZ1  1 
ATOM   1438  H  HZ2  . LYS   A 1 92  ? 14.799  -5.603  17.269  1.00 80.37  ?  91  LYS   B HZ2  1 
ATOM   1439  H  HZ3  . LYS   A 1 92  ? 15.362  -4.586  18.134  1.00 80.37  ?  91  LYS   B HZ3  1 
ATOM   1440  N  N    . LYS   A 1 93  ? 14.127  -7.303  24.371  1.00 36.16  ?  92  LYS   B N    1 
ATOM   1441  C  CA   . LYS   A 1 93  ? 14.656  -8.579  24.828  1.00 39.36  ?  92  LYS   B CA   1 
ATOM   1442  C  C    . LYS   A 1 93  ? 14.469  -8.796  26.323  1.00 37.49  ?  92  LYS   B C    1 
ATOM   1443  O  O    . LYS   A 1 93  ? 14.732  -9.897  26.812  1.00 40.36  ?  92  LYS   B O    1 
ATOM   1444  C  CB   . LYS   A 1 93  ? 16.160  -8.707  24.498  1.00 47.72  ?  92  LYS   B CB   1 
ATOM   1445  C  CG   . LYS   A 1 93  ? 16.480  -8.986  23.042  1.00 49.19  ?  92  LYS   B CG   1 
ATOM   1446  C  CD   . LYS   A 1 93  ? 17.964  -8.621  22.733  1.00 49.74  ?  92  LYS   B CD   1 
ATOM   1447  C  CE   . LYS   A 1 93  ? 18.165  -8.188  21.283  1.00 54.53  ?  92  LYS   B CE   1 
ATOM   1448  N  NZ   . LYS   A 1 93  ? 19.523  -7.615  21.028  1.00 58.37  ?  92  LYS   B NZ   1 
ATOM   1449  H  H    . LYS   A 1 93  ? 14.654  -6.635  24.492  1.00 43.39  ?  92  LYS   B H    1 
ATOM   1450  H  HA   . LYS   A 1 93  ? 14.190  -9.283  24.350  1.00 47.23  ?  92  LYS   B HA   1 
ATOM   1451  H  HB2  . LYS   A 1 93  ? 16.597  -7.875  24.737  1.00 57.27  ?  92  LYS   B HB2  1 
ATOM   1452  H  HB3  . LYS   A 1 93  ? 16.527  -9.437  25.020  1.00 57.27  ?  92  LYS   B HB3  1 
ATOM   1453  H  HG2  . LYS   A 1 93  ? 16.347  -9.928  22.854  1.00 59.03  ?  92  LYS   B HG2  1 
ATOM   1454  H  HG3  . LYS   A 1 93  ? 15.905  -8.450  22.474  1.00 59.03  ?  92  LYS   B HG3  1 
ATOM   1455  H  HD2  . LYS   A 1 93  ? 18.238  -7.888  23.307  1.00 59.69  ?  92  LYS   B HD2  1 
ATOM   1456  H  HD3  . LYS   A 1 93  ? 18.523  -9.397  22.896  1.00 59.69  ?  92  LYS   B HD3  1 
ATOM   1457  H  HE2  . LYS   A 1 93  ? 18.052  -8.958  20.705  1.00 65.44  ?  92  LYS   B HE2  1 
ATOM   1458  H  HE3  . LYS   A 1 93  ? 17.509  -7.508  21.063  1.00 65.44  ?  92  LYS   B HE3  1 
ATOM   1459  H  HZ1  . LYS   A 1 93  ? 20.138  -8.257  21.076  1.00 70.05  ?  92  LYS   B HZ1  1 
ATOM   1460  H  HZ2  . LYS   A 1 93  ? 19.552  -7.249  20.217  1.00 70.05  ?  92  LYS   B HZ2  1 
ATOM   1461  H  HZ3  . LYS   A 1 93  ? 19.709  -6.991  21.634  1.00 70.05  ?  92  LYS   B HZ3  1 
ATOM   1462  N  N    . TRP   A 1 94  ? 14.066  -7.776  27.069  1.00 38.80  ?  93  TRP   B N    1 
ATOM   1463  C  CA   . TRP   A 1 94  ? 13.674  -8.007  28.455  1.00 38.42  ?  93  TRP   B CA   1 
ATOM   1464  C  C    . TRP   A 1 94  ? 12.508  -8.982  28.506  1.00 40.30  ?  93  TRP   B C    1 
ATOM   1465  O  O    . TRP   A 1 94  ? 11.841  -9.228  27.507  1.00 41.58  ?  93  TRP   B O    1 
ATOM   1466  C  CB   . TRP   A 1 94  ? 13.288  -6.698  29.133  1.00 36.55  ?  93  TRP   B CB   1 
ATOM   1467  C  CG   . TRP   A 1 94  ? 14.488  -5.831  29.342  1.00 35.15  ?  93  TRP   B CG   1 
ATOM   1468  C  CD1  . TRP   A 1 94  ? 15.804  -6.172  29.131  1.00 33.19  ?  93  TRP   B CD1  1 
ATOM   1469  C  CD2  . TRP   A 1 94  ? 14.492  -4.476  29.787  1.00 31.23  ?  93  TRP   B CD2  1 
ATOM   1470  N  NE1  . TRP   A 1 94  ? 16.625  -5.113  29.451  1.00 30.38  ?  93  TRP   B NE1  1 
ATOM   1471  C  CE2  . TRP   A 1 94  ? 15.839  -4.054  29.841  1.00 34.23  ?  93  TRP   B CE2  1 
ATOM   1472  C  CE3  . TRP   A 1 94  ? 13.489  -3.576  30.144  1.00 33.32  ?  93  TRP   B CE3  1 
ATOM   1473  C  CZ2  . TRP   A 1 94  ? 16.194  -2.781  30.250  1.00 30.40  ?  93  TRP   B CZ2  1 
ATOM   1474  C  CZ3  . TRP   A 1 94  ? 13.845  -2.306  30.539  1.00 26.84  ?  93  TRP   B CZ3  1 
ATOM   1475  C  CH2  . TRP   A 1 94  ? 15.186  -1.933  30.623  1.00 32.81  ?  93  TRP   B CH2  1 
ATOM   1476  H  H    . TRP   A 1 94  ? 14.010  -6.960  26.805  1.00 46.56  ?  93  TRP   B H    1 
ATOM   1477  H  HA   . TRP   A 1 94  ? 14.419  -8.385  28.947  1.00 46.10  ?  93  TRP   B HA   1 
ATOM   1478  H  HB2  . TRP   A 1 94  ? 12.657  -6.219  28.574  1.00 43.87  ?  93  TRP   B HB2  1 
ATOM   1479  H  HB3  . TRP   A 1 94  ? 12.890  -6.887  29.997  1.00 43.87  ?  93  TRP   B HB3  1 
ATOM   1480  H  HD1  . TRP   A 1 94  ? 16.097  -6.998  28.819  1.00 39.83  ?  93  TRP   B HD1  1 
ATOM   1481  H  HE1  . TRP   A 1 94  ? 17.484  -5.113  29.413  1.00 36.45  ?  93  TRP   B HE1  1 
ATOM   1482  H  HE3  . TRP   A 1 94  ? 12.594  -3.830  30.117  1.00 39.98  ?  93  TRP   B HE3  1 
ATOM   1483  H  HZ2  . TRP   A 1 94  ? 17.084  -2.512  30.270  1.00 36.48  ?  93  TRP   B HZ2  1 
ATOM   1484  H  HZ3  . TRP   A 1 94  ? 13.183  -1.689  30.753  1.00 32.21  ?  93  TRP   B HZ3  1 
ATOM   1485  H  HH2  . TRP   A 1 94  ? 15.402  -1.085  30.940  1.00 39.37  ?  93  TRP   B HH2  1 
ATOM   1486  N  N    . LYS   A 1 95  ? 12.312  -9.582  29.674  1.00 36.67  ?  94  LYS   B N    1 
ATOM   1487  C  CA   . LYS   A 1 95  ? 11.162  -10.419 29.969  1.00 38.16  ?  94  LYS   B CA   1 
ATOM   1488  C  C    . LYS   A 1 95  ? 10.221  -9.679  30.924  1.00 38.47  ?  94  LYS   B C    1 
ATOM   1489  O  O    . LYS   A 1 95  ? 10.652  -9.061  31.920  1.00 34.78  ?  94  LYS   B O    1 
ATOM   1490  C  CB   . LYS   A 1 95  ? 11.567  -11.762 30.588  1.00 29.50  ?  94  LYS   B CB   1 
ATOM   1491  C  CG   . LYS   A 1 95  ? 12.354  -12.712 29.690  1.00 34.86  ?  94  LYS   B CG   1 
ATOM   1492  C  CD   . LYS   A 1 95  ? 12.281  -12.347 28.223  1.00 36.99  ?  94  LYS   B CD   1 
ATOM   1493  C  CE   . LYS   A 1 95  ? 12.440  -13.591 27.317  1.00 59.71  ?  94  LYS   B CE   1 
ATOM   1494  N  NZ   . LYS   A 1 95  ? 12.573  -13.157 25.875  1.00 65.15  ?  94  LYS   B NZ   1 
ATOM   1495  H  H    . LYS   A 1 95  ? 12.856  -9.515  30.337  1.00 44.00  ?  94  LYS   B H    1 
ATOM   1496  H  HA   . LYS   A 1 95  ? 10.693  -10.607 29.141  1.00 45.79  ?  94  LYS   B HA   1 
ATOM   1497  H  HB2  . LYS   A 1 95  ? 12.119  -11.582 31.365  1.00 35.40  ?  94  LYS   B HB2  1 
ATOM   1498  H  HB3  . LYS   A 1 95  ? 10.759  -12.227 30.855  1.00 35.40  ?  94  LYS   B HB3  1 
ATOM   1499  H  HG2  . LYS   A 1 95  ? 13.287  -12.694 29.954  1.00 41.83  ?  94  LYS   B HG2  1 
ATOM   1500  H  HG3  . LYS   A 1 95  ? 11.998  -13.608 29.791  1.00 41.83  ?  94  LYS   B HG3  1 
ATOM   1501  H  HD2  . LYS   A 1 95  ? 11.419  -11.943 28.035  1.00 44.38  ?  94  LYS   B HD2  1 
ATOM   1502  H  HD3  . LYS   A 1 95  ? 12.992  -11.723 28.011  1.00 44.38  ?  94  LYS   B HD3  1 
ATOM   1503  H  HE2  . LYS   A 1 95  ? 13.238  -14.081 27.570  1.00 71.66  ?  94  LYS   B HE2  1 
ATOM   1504  H  HE3  . LYS   A 1 95  ? 11.660  -14.161 27.402  1.00 71.66  ?  94  LYS   B HE3  1 
ATOM   1505  H  HZ1  . LYS   A 1 95  ? 12.605  -13.870 25.344  1.00 78.18  ?  94  LYS   B HZ1  1 
ATOM   1506  H  HZ2  . LYS   A 1 95  ? 11.874  -12.656 25.643  1.00 78.18  ?  94  LYS   B HZ2  1 
ATOM   1507  H  HZ3  . LYS   A 1 95  ? 13.317  -12.682 25.767  1.00 78.18  ?  94  LYS   B HZ3  1 
ATOM   1508  N  N    . TYR   A 1 96  ? 8.922   -9.775  30.644  1.00 37.67  ?  95  TYR   B N    1 
ATOM   1509  C  CA   . TYR   A 1 96  ? 7.914   -9.014  31.371  1.00 34.77  ?  95  TYR   B CA   1 
ATOM   1510  C  C    . TYR   A 1 96  ? 6.932   -9.950  32.045  1.00 31.27  ?  95  TYR   B C    1 
ATOM   1511  O  O    . TYR   A 1 96  ? 5.758   -9.978  31.695  1.00 37.68  ?  95  TYR   B O    1 
ATOM   1512  C  CB   . TYR   A 1 96  ? 7.231   -8.081  30.388  1.00 25.57  ?  95  TYR   B CB   1 
ATOM   1513  C  CG   . TYR   A 1 96  ? 8.170   -7.112  29.744  1.00 36.78  ?  95  TYR   B CG   1 
ATOM   1514  C  CD1  . TYR   A 1 96  ? 8.542   -5.958  30.407  1.00 32.74  ?  95  TYR   B CD1  1 
ATOM   1515  C  CD2  . TYR   A 1 96  ? 8.702   -7.343  28.471  1.00 33.55  ?  95  TYR   B CD2  1 
ATOM   1516  C  CE1  . TYR   A 1 96  ? 9.407   -5.034  29.824  1.00 28.00  ?  95  TYR   B CE1  1 
ATOM   1517  C  CE2  . TYR   A 1 96  ? 9.545   -6.408  27.875  1.00 38.10  ?  95  TYR   B CE2  1 
ATOM   1518  C  CZ   . TYR   A 1 96  ? 9.903   -5.271  28.577  1.00 37.79  ?  95  TYR   B CZ   1 
ATOM   1519  O  OH   . TYR   A 1 96  ? 10.757  -4.363  28.026  1.00 41.58  ?  95  TYR   B OH   1 
ATOM   1520  H  H    . TYR   A 1 96  ? 8.599   -10.281 30.029  1.00 45.20  ?  95  TYR   B H    1 
ATOM   1521  H  HA   . TYR   A 1 96  ? 8.318   -8.504  32.091  1.00 41.73  ?  95  TYR   B HA   1 
ATOM   1522  H  HB2  . TYR   A 1 96  ? 6.821   -8.610  29.686  1.00 30.69  ?  95  TYR   B HB2  1 
ATOM   1523  H  HB3  . TYR   A 1 96  ? 6.552   -7.571  30.858  1.00 30.69  ?  95  TYR   B HB3  1 
ATOM   1524  H  HD1  . TYR   A 1 96  ? 8.209   -5.795  31.260  1.00 39.29  ?  95  TYR   B HD1  1 
ATOM   1525  H  HD2  . TYR   A 1 96  ? 8.491   -8.128  28.019  1.00 40.26  ?  95  TYR   B HD2  1 
ATOM   1526  H  HE1  . TYR   A 1 96  ? 9.644   -4.261  30.282  1.00 33.61  ?  95  TYR   B HE1  1 
ATOM   1527  H  HE2  . TYR   A 1 96  ? 9.865   -6.547  27.013  1.00 45.72  ?  95  TYR   B HE2  1 
ATOM   1528  H  HH   . TYR   A 1 96  ? 10.928  -4.575  27.231  1.00 49.89  ?  95  TYR   B HH   1 
ATOM   1529  N  N    . PRO   A 1 97  ? 7.369   -10.701 33.034  1.00 34.65  ?  96  PRO   B N    1 
ATOM   1530  C  CA   . PRO   A 1 97  ? 6.437   -11.618 33.693  1.00 33.68  ?  96  PRO   B CA   1 
ATOM   1531  C  C    . PRO   A 1 97  ? 5.297   -10.878 34.392  1.00 40.32  ?  96  PRO   B C    1 
ATOM   1532  O  O    . PRO   A 1 97  ? 5.452   -9.748  34.891  1.00 34.88  ?  96  PRO   B O    1 
ATOM   1533  C  CB   . PRO   A 1 97  ? 7.323   -12.374 34.709  1.00 34.46  ?  96  PRO   B CB   1 
ATOM   1534  C  CG   . PRO   A 1 97  ? 8.553   -11.456 34.997  1.00 23.85  ?  96  PRO   B CG   1 
ATOM   1535  C  CD   . PRO   A 1 97  ? 8.670   -10.585 33.725  1.00 33.01  ?  96  PRO   B CD   1 
ATOM   1536  H  HA   . PRO   A 1 97  ? 6.068   -12.241 33.047  1.00 40.41  ?  96  PRO   B HA   1 
ATOM   1537  H  HB2  . PRO   A 1 97  ? 6.818   -12.534 35.522  1.00 41.35  ?  96  PRO   B HB2  1 
ATOM   1538  H  HB3  . PRO   A 1 97  ? 7.609   -13.217 34.325  1.00 41.35  ?  96  PRO   B HB3  1 
ATOM   1539  H  HG2  . PRO   A 1 97  ? 8.389   -10.911 35.782  1.00 28.62  ?  96  PRO   B HG2  1 
ATOM   1540  H  HG3  . PRO   A 1 97  ? 9.349   -11.995 35.128  1.00 28.62  ?  96  PRO   B HG3  1 
ATOM   1541  H  HD2  . PRO   A 1 97  ? 8.840   -9.661  33.967  1.00 39.61  ?  96  PRO   B HD2  1 
ATOM   1542  H  HD3  . PRO   A 1 97  ? 9.382   -10.916 33.156  1.00 39.61  ?  96  PRO   B HD3  1 
ATOM   1543  N  N    . GLN   A 1 98  ? 4.120   -11.533 34.378  1.00 36.30  ?  97  GLN   B N    1 
ATOM   1544  C  CA   . GLN   A 1 98  ? 3.062   -11.257 35.336  1.00 35.07  ?  97  GLN   B CA   1 
ATOM   1545  C  C    . GLN   A 1 98  ? 3.509   -11.779 36.692  1.00 33.57  ?  97  GLN   B C    1 
ATOM   1546  O  O    . GLN   A 1 98  ? 4.039   -12.888 36.810  1.00 40.16  ?  97  GLN   B O    1 
ATOM   1547  C  CB   . GLN   A 1 98  ? 1.753   -11.907 34.896  1.00 36.40  ?  97  GLN   B CB   1 
ATOM   1548  C  CG   . GLN   A 1 98  ? 1.208   -11.350 33.585  1.00 29.88  ?  97  GLN   B CG   1 
ATOM   1549  C  CD   . GLN   A 1 98  ? 0.849   -9.871  33.654  1.00 37.50  ?  97  GLN   B CD   1 
ATOM   1550  O  OE1  . GLN   A 1 98  ? 1.446   -9.043  32.938  1.00 44.49  ?  97  GLN   B OE1  1 
ATOM   1551  N  NE2  . GLN   A 1 98  ? -0.144  -9.530  34.491  1.00 50.37  ?  97  GLN   B NE2  1 
ATOM   1552  H  H    . GLN   A 1 98  ? 3.918   -12.147 33.811  1.00 43.56  ?  97  GLN   B H    1 
ATOM   1553  H  HA   . GLN   A 1 98  ? 2.890   -10.304 35.399  1.00 42.08  ?  97  GLN   B HA   1 
ATOM   1554  H  HB2  . GLN   A 1 98  ? 1.901   -12.858 34.776  1.00 43.68  ?  97  GLN   B HB2  1 
ATOM   1555  H  HB3  . GLN   A 1 98  ? 1.085   -11.759 35.583  1.00 43.68  ?  97  GLN   B HB3  1 
ATOM   1556  H  HG2  . GLN   A 1 98  ? 1.880   -11.460 32.894  1.00 35.85  ?  97  GLN   B HG2  1 
ATOM   1557  H  HG3  . GLN   A 1 98  ? 0.405   -11.839 33.347  1.00 35.85  ?  97  GLN   B HG3  1 
ATOM   1558  H  HE21 . GLN   A 1 98  ? -0.543  -10.135 34.955  1.00 60.44  ?  97  GLN   B HE21 1 
ATOM   1559  H  HE22 . GLN   A 1 98  ? -0.382  -8.707  34.564  1.00 60.44  ?  97  GLN   B HE22 1 
ATOM   1560  N  N    . VAL   A 1 99  ? 3.358   -10.949 37.706  1.00 30.99  ?  98  VAL   B N    1 
ATOM   1561  C  CA   . VAL   A 1 99  ? 3.816   -11.241 39.058  1.00 28.38  ?  98  VAL   B CA   1 
ATOM   1562  C  C    . VAL   A 1 99  ? 2.782   -10.603 39.971  1.00 31.95  ?  98  VAL   B C    1 
ATOM   1563  O  O    . VAL   A 1 99  ? 2.639   -9.378  39.971  1.00 31.27  ?  98  VAL   B O    1 
ATOM   1564  C  CB   . VAL   A 1 99  ? 5.233   -10.674 39.326  1.00 34.71  ?  98  VAL   B CB   1 
ATOM   1565  C  CG1  . VAL   A 1 99  ? 5.648   -10.941 40.791  1.00 30.20  ?  98  VAL   B CG1  1 
ATOM   1566  C  CG2  . VAL   A 1 99  ? 6.246   -11.288 38.374  1.00 32.02  ?  98  VAL   B CG2  1 
ATOM   1567  H  H    . VAL   A 1 99  ? 2.979   -10.180 37.639  1.00 37.18  ?  98  VAL   B H    1 
ATOM   1568  H  HA   . VAL   A 1 99  ? 3.877   -12.197 39.211  1.00 34.05  ?  98  VAL   B HA   1 
ATOM   1569  H  HB   . VAL   A 1 99  ? 5.218   -9.716  39.177  1.00 41.65  ?  98  VAL   B HB   1 
ATOM   1570  H  HG11 . VAL   A 1 99  ? 6.616   -10.967 40.846  1.00 36.24  ?  98  VAL   B HG11 1 
ATOM   1571  H  HG12 . VAL   A 1 99  ? 5.303   -10.229 41.352  1.00 36.24  ?  98  VAL   B HG12 1 
ATOM   1572  H  HG13 . VAL   A 1 99  ? 5.278   -11.792 41.074  1.00 36.24  ?  98  VAL   B HG13 1 
ATOM   1573  H  HG21 . VAL   A 1 99  ? 7.134   -10.984 38.619  1.00 38.42  ?  98  VAL   B HG21 1 
ATOM   1574  H  HG22 . VAL   A 1 99  ? 6.197   -12.255 38.442  1.00 38.42  ?  98  VAL   B HG22 1 
ATOM   1575  H  HG23 . VAL   A 1 99  ? 6.038   -11.009 37.469  1.00 38.42  ?  98  VAL   B HG23 1 
ATOM   1576  N  N    . ASN   A 1 100 ? 2.014   -11.405 40.711  1.00 37.44  ?  99  ASN   B N    1 
ATOM   1577  C  CA   . ASN   A 1 100 ? 0.961   -10.864 41.587  1.00 36.58  ?  99  ASN   B CA   1 
ATOM   1578  C  C    . ASN   A 1 100 ? -0.058  -9.997  40.835  1.00 35.37  ?  99  ASN   B C    1 
ATOM   1579  O  O    . ASN   A 1 100 ? -0.434  -8.916  41.285  1.00 35.27  ?  99  ASN   B O    1 
ATOM   1580  C  CB   . ASN   A 1 100 ? 1.614   -10.068 42.711  1.00 41.89  ?  99  ASN   B CB   1 
ATOM   1581  C  CG   . ASN   A 1 100 ? 0.652   -9.715  43.804  1.00 48.06  ?  99  ASN   B CG   1 
ATOM   1582  O  OD1  . ASN   A 1 100 ? -0.130  -10.553 44.248  1.00 50.51  ?  99  ASN   B OD1  1 
ATOM   1583  N  ND2  . ASN   A 1 100 ? 0.717   -8.461  44.267  1.00 46.37  ?  99  ASN   B ND2  1 
ATOM   1584  H  H    . ASN   A 1 100 ? 2.080   -12.262 40.726  1.00 44.93  ?  99  ASN   B H    1 
ATOM   1585  H  HA   . ASN   A 1 100 ? 0.453   -11.605 41.951  1.00 43.89  ?  99  ASN   B HA   1 
ATOM   1586  H  HB2  . ASN   A 1 100 ? 2.329   -10.597 43.099  1.00 50.27  ?  99  ASN   B HB2  1 
ATOM   1587  H  HB3  . ASN   A 1 100 ? 1.972   -9.243  42.347  1.00 50.27  ?  99  ASN   B HB3  1 
ATOM   1588  H  HD21 . ASN   A 1 100 ? 1.288   -7.910  43.937  1.00 55.64  ?  99  ASN   B HD21 1 
ATOM   1589  H  HD22 . ASN   A 1 100 ? 0.186   -8.207  44.894  1.00 55.64  ?  99  ASN   B HD22 1 
ATOM   1590  N  N    . GLY   A 1 101 ? -0.497  -10.459 39.665  1.00 34.24  ?  100 GLY   B N    1 
ATOM   1591  C  CA   . GLY   A 1 101 ? -1.483  -9.745  38.872  1.00 29.19  ?  100 GLY   B CA   1 
ATOM   1592  C  C    . GLY   A 1 101 ? -0.975  -8.520  38.136  1.00 37.91  ?  100 GLY   B C    1 
ATOM   1593  O  O    . GLY   A 1 101 ? -1.773  -7.808  37.518  1.00 34.89  ?  100 GLY   B O    1 
ATOM   1594  H  H    . GLY   A 1 101 ? -0.233  -11.195 39.307  1.00 41.08  ?  100 GLY   B H    1 
ATOM   1595  H  HA2  . GLY   A 1 101 ? -1.845  -10.355 38.210  1.00 35.03  ?  100 GLY   B HA2  1 
ATOM   1596  H  HA3  . GLY   A 1 101 ? -2.199  -9.456  39.460  1.00 35.03  ?  100 GLY   B HA3  1 
ATOM   1597  N  N    . LEU   A 1 102 ? 0.326   -8.244  38.171  1.00 38.58  ?  101 LEU   B N    1 
ATOM   1598  C  CA   . LEU   A 1 102 ? 0.889   -7.028  37.601  1.00 36.63  ?  101 LEU   B CA   1 
ATOM   1599  C  C    . LEU   A 1 102 ? 1.991   -7.386  36.619  1.00 30.89  ?  101 LEU   B C    1 
ATOM   1600  O  O    . LEU   A 1 102 ? 2.643   -8.418  36.742  1.00 33.74  ?  101 LEU   B O    1 
ATOM   1601  C  CB   . LEU   A 1 102 ? 1.446   -6.105  38.719  1.00 33.74  ?  101 LEU   B CB   1 
ATOM   1602  C  CG   . LEU   A 1 102 ? 0.384   -5.626  39.706  1.00 36.50  ?  101 LEU   B CG   1 
ATOM   1603  C  CD1  . LEU   A 1 102 ? 0.922   -5.053  40.973  1.00 41.50  ?  101 LEU   B CD1  1 
ATOM   1604  C  CD2  . LEU   A 1 102 ? -0.493  -4.588  38.987  1.00 33.75  ?  101 LEU   B CD2  1 
ATOM   1605  H  H    . LEU   A 1 102 ? 0.915   -8.759  38.528  1.00 46.29  ?  101 LEU   B H    1 
ATOM   1606  H  HA   . LEU   A 1 102 ? 0.207   -6.541  37.112  1.00 43.96  ?  101 LEU   B HA   1 
ATOM   1607  H  HB2  . LEU   A 1 102 ? 2.118   -6.594  39.220  1.00 40.48  ?  101 LEU   B HB2  1 
ATOM   1608  H  HB3  . LEU   A 1 102 ? 1.843   -5.322  38.307  1.00 40.48  ?  101 LEU   B HB3  1 
ATOM   1609  H  HG   . LEU   A 1 102 ? -0.129  -6.399  39.989  1.00 43.80  ?  101 LEU   B HG   1 
ATOM   1610  H  HD11 . LEU   A 1 102 ? 0.181   -4.794  41.543  1.00 49.80  ?  101 LEU   B HD11 1 
ATOM   1611  H  HD12 . LEU   A 1 102 ? 1.463   -5.724  41.419  1.00 49.80  ?  101 LEU   B HD12 1 
ATOM   1612  H  HD13 . LEU   A 1 102 ? 1.465   -4.277  40.763  1.00 49.80  ?  101 LEU   B HD13 1 
ATOM   1613  H  HD21 . LEU   A 1 102 ? -0.853  -3.969  39.642  1.00 40.50  ?  101 LEU   B HD21 1 
ATOM   1614  H  HD22 . LEU   A 1 102 ? 0.050   -4.108  38.342  1.00 40.50  ?  101 LEU   B HD22 1 
ATOM   1615  H  HD23 . LEU   A 1 102 ? -1.217  -5.047  38.533  1.00 40.50  ?  101 LEU   B HD23 1 
ATOM   1616  N  N    . THR   A 1 103 ? 2.157   -6.553  35.608  1.00 34.04  ?  102 THR   B N    1 
ATOM   1617  C  CA   . THR   A 1 103 ? 3.283   -6.687  34.695  1.00 27.13  ?  102 THR   B CA   1 
ATOM   1618  C  C    . THR   A 1 103 ? 4.529   -6.181  35.398  1.00 36.17  ?  102 THR   B C    1 
ATOM   1619  O  O    . THR   A 1 103 ? 4.568   -5.021  35.809  1.00 30.76  ?  102 THR   B O    1 
ATOM   1620  C  CB   . THR   A 1 103 ? 3.073   -5.864  33.436  1.00 39.25  ?  102 THR   B CB   1 
ATOM   1621  O  OG1  . THR   A 1 103 ? 1.820   -6.199  32.866  1.00 34.32  ?  102 THR   B OG1  1 
ATOM   1622  C  CG2  . THR   A 1 103 ? 4.189   -6.138  32.426  1.00 40.33  ?  102 THR   B CG2  1 
ATOM   1623  H  H    . THR   A 1 103 ? 1.630   -5.898  35.426  1.00 40.85  ?  102 THR   B H    1 
ATOM   1624  H  HA   . THR   A 1 103 ? 3.375   -7.620  34.446  1.00 32.55  ?  102 THR   B HA   1 
ATOM   1625  H  HB   . THR   A 1 103 ? 3.088   -4.918  33.651  1.00 47.10  ?  102 THR   B HB   1 
ATOM   1626  H  HG1  . THR   A 1 103 ? 1.838   -6.988  32.577  1.00 41.19  ?  102 THR   B HG1  1 
ATOM   1627  H  HG21 . THR   A 1 103 ? 3.857   -6.015  31.523  1.00 48.40  ?  102 THR   B HG21 1 
ATOM   1628  H  HG22 . THR   A 1 103 ? 4.928   -5.527  32.575  1.00 48.40  ?  102 THR   B HG22 1 
ATOM   1629  H  HG23 . THR   A 1 103 ? 4.508   -7.048  32.523  1.00 48.40  ?  102 THR   B HG23 1 
ATOM   1630  N  N    . SER   A 1 104 ? 5.557   -7.010  35.492  1.00 35.28  ?  103 SER   B N    1 
ATOM   1631  C  CA   . SER   A 1 104 ? 6.851   -6.629  36.051  1.00 31.05  ?  103 SER   B CA   1 
ATOM   1632  C  C    . SER   A 1 104 ? 7.923   -6.754  34.956  1.00 29.90  ?  103 SER   B C    1 
ATOM   1633  O  O    . SER   A 1 104 ? 7.631   -6.933  33.759  1.00 33.59  ?  103 SER   B O    1 
ATOM   1634  C  CB   . SER   A 1 104 ? 7.150   -7.481  37.299  1.00 31.99  ?  103 SER   B CB   1 
ATOM   1635  O  OG   . SER   A 1 104 ? 8.136   -6.888  38.129  1.00 33.41  ?  103 SER   B OG   1 
ATOM   1636  H  H    . SER   A 1 104 ? 5.532   -7.829  35.229  1.00 42.33  ?  103 SER   B H    1 
ATOM   1637  H  HA   . SER   A 1 104 ? 6.833   -5.701  36.332  1.00 37.26  ?  103 SER   B HA   1 
ATOM   1638  H  HB2  . SER   A 1 104 ? 6.332   -7.580  37.810  1.00 38.39  ?  103 SER   B HB2  1 
ATOM   1639  H  HB3  . SER   A 1 104 ? 7.469   -8.351  37.011  1.00 38.39  ?  103 SER   B HB3  1 
ATOM   1640  H  HG   . SER   A 1 104 ? 8.224   -7.335  38.835  1.00 40.10  ?  103 SER   B HG   1 
ATOM   1641  N  N    . ILE   A 1 105 ? 9.183   -6.655  35.386  1.00 29.83  ?  104 ILE   B N    1 
ATOM   1642  C  CA   . ILE   A 1 105 ? 10.323  -6.841  34.493  1.00 25.18  ?  104 ILE   B CA   1 
ATOM   1643  C  C    . ILE   A 1 105 ? 11.372  -7.694  35.195  1.00 25.80  ?  104 ILE   B C    1 
ATOM   1644  O  O    . ILE   A 1 105 ? 11.839  -7.349  36.295  1.00 24.20  ?  104 ILE   B O    1 
ATOM   1645  C  CB   . ILE   A 1 105 ? 10.980  -5.524  34.042  1.00 32.71  ?  104 ILE   B CB   1 
ATOM   1646  C  CG1  . ILE   A 1 105 ? 9.956   -4.386  33.930  1.00 29.79  ?  104 ILE   B CG1  1 
ATOM   1647  C  CG2  . ILE   A 1 105 ? 11.684  -5.667  32.665  1.00 25.79  ?  104 ILE   B CG2  1 
ATOM   1648  C  CD1  . ILE   A 1 105 ? 10.580  -3.011  33.652  1.00 27.80  ?  104 ILE   B CD1  1 
ATOM   1649  H  H    . ILE   A 1 105 ? 9.402   -6.479  36.199  1.00 35.79  ?  104 ILE   B H    1 
ATOM   1650  H  HA   . ILE   A 1 105 ? 9.997   -7.312  33.711  1.00 30.22  ?  104 ILE   B HA   1 
ATOM   1651  H  HB   . ILE   A 1 105 ? 11.634  -5.314  34.727  1.00 39.25  ?  104 ILE   B HB   1 
ATOM   1652  H  HG12 . ILE   A 1 105 ? 9.347   -4.587  33.202  1.00 35.75  ?  104 ILE   B HG12 1 
ATOM   1653  H  HG13 . ILE   A 1 105 ? 9.466   -4.325  34.765  1.00 35.75  ?  104 ILE   B HG13 1 
ATOM   1654  H  HG21 . ILE   A 1 105 ? 12.158  -4.845  32.466  1.00 30.95  ?  104 ILE   B HG21 1 
ATOM   1655  H  HG22 . ILE   A 1 105 ? 12.309  -6.408  32.706  1.00 30.95  ?  104 ILE   B HG22 1 
ATOM   1656  H  HG23 . ILE   A 1 105 ? 11.014  -5.836  31.984  1.00 30.95  ?  104 ILE   B HG23 1 
ATOM   1657  H  HD11 . ILE   A 1 105 ? 9.873   -2.350  33.587  1.00 33.36  ?  104 ILE   B HD11 1 
ATOM   1658  H  HD12 . ILE   A 1 105 ? 11.180  -2.783  34.380  1.00 33.36  ?  104 ILE   B HD12 1 
ATOM   1659  H  HD13 . ILE   A 1 105 ? 11.073  -3.050  32.817  1.00 33.36  ?  104 ILE   B HD13 1 
ATOM   1660  N  N    . LYS   A 1 106 ? 11.777  -8.791  34.545  1.00 28.58  ?  105 LYS   B N    1 
ATOM   1661  C  CA   . LYS   A 1 106 ? 12.968  -9.497  35.017  1.00 31.82  ?  105 LYS   B CA   1 
ATOM   1662  C  C    . LYS   A 1 106 ? 14.133  -8.515  35.091  1.00 27.99  ?  105 LYS   B C    1 
ATOM   1663  O  O    . LYS   A 1 106 ? 14.264  -7.632  34.231  1.00 22.28  ?  105 LYS   B O    1 
ATOM   1664  C  CB   . LYS   A 1 106 ? 13.385  -10.643 34.110  1.00 30.97  ?  105 LYS   B CB   1 
ATOM   1665  C  CG   . LYS   A 1 106 ? 14.216  -11.660 34.795  1.00 31.77  ?  105 LYS   B CG   1 
ATOM   1666  C  CD   . LYS   A 1 106 ? 14.372  -12.867 33.924  1.00 34.80  ?  105 LYS   B CD   1 
ATOM   1667  C  CE   . LYS   A 1 106 ? 15.544  -13.706 34.378  1.00 36.21  ?  105 LYS   B CE   1 
ATOM   1668  N  NZ   . LYS   A 1 106 ? 16.164  -14.362 33.201  1.00 56.93  ?  105 LYS   B NZ   1 
ATOM   1669  H  H    . LYS   A 1 106 ? 11.394  -9.132  33.855  1.00 34.29  ?  105 LYS   B H    1 
ATOM   1670  H  HA   . LYS   A 1 106 ? 12.758  -9.878  35.884  1.00 38.19  ?  105 LYS   B HA   1 
ATOM   1671  H  HB2  . LYS   A 1 106 ? 12.588  -11.084 33.776  1.00 37.17  ?  105 LYS   B HB2  1 
ATOM   1672  H  HB3  . LYS   A 1 106 ? 13.900  -10.286 33.370  1.00 37.17  ?  105 LYS   B HB3  1 
ATOM   1673  H  HG2  . LYS   A 1 106 ? 15.095  -11.294 34.979  1.00 38.12  ?  105 LYS   B HG2  1 
ATOM   1674  H  HG3  . LYS   A 1 106 ? 13.788  -11.928 35.623  1.00 38.12  ?  105 LYS   B HG3  1 
ATOM   1675  H  HD2  . LYS   A 1 106 ? 13.568  -13.408 33.972  1.00 41.76  ?  105 LYS   B HD2  1 
ATOM   1676  H  HD3  . LYS   A 1 106 ? 14.529  -12.587 33.008  1.00 41.76  ?  105 LYS   B HD3  1 
ATOM   1677  H  HE2  . LYS   A 1 106 ? 16.205  -13.142 34.808  1.00 43.45  ?  105 LYS   B HE2  1 
ATOM   1678  H  HE3  . LYS   A 1 106 ? 15.239  -14.390 34.994  1.00 43.45  ?  105 LYS   B HE3  1 
ATOM   1679  H  HZ1  . LYS   A 1 106 ? 16.922  -14.762 33.440  1.00 68.32  ?  105 LYS   B HZ1  1 
ATOM   1680  H  HZ2  . LYS   A 1 106 ? 15.610  -14.971 32.864  1.00 68.32  ?  105 LYS   B HZ2  1 
ATOM   1681  H  HZ3  . LYS   A 1 106 ? 16.343  -13.756 32.574  1.00 68.32  ?  105 LYS   B HZ3  1 
ATOM   1682  N  N    . TRP   A 1 107 ? 14.974  -8.670  36.122  1.00 26.14  ?  106 TRP   B N    1 
ATOM   1683  C  CA   . TRP   A 1 107 ? 16.124  -7.777  36.301  1.00 29.55  ?  106 TRP   B CA   1 
ATOM   1684  C  C    . TRP   A 1 107 ? 17.043  -7.888  35.095  1.00 28.10  ?  106 TRP   B C    1 
ATOM   1685  O  O    . TRP   A 1 107 ? 17.410  -8.997  34.693  1.00 26.13  ?  106 TRP   B O    1 
ATOM   1686  C  CB   . TRP   A 1 107 ? 16.936  -8.123  37.574  1.00 26.07  ?  106 TRP   B CB   1 
ATOM   1687  C  CG   . TRP   A 1 107 ? 17.939  -7.047  37.863  1.00 31.49  ?  106 TRP   B CG   1 
ATOM   1688  C  CD1  . TRP   A 1 107 ? 17.720  -5.916  38.580  1.00 28.06  ?  106 TRP   B CD1  1 
ATOM   1689  C  CD2  . TRP   A 1 107 ? 19.307  -6.964  37.388  1.00 29.08  ?  106 TRP   B CD2  1 
ATOM   1690  N  NE1  . TRP   A 1 107 ? 18.846  -5.135  38.585  1.00 32.06  ?  106 TRP   B NE1  1 
ATOM   1691  C  CE2  . TRP   A 1 107 ? 19.834  -5.754  37.857  1.00 30.66  ?  106 TRP   B CE2  1 
ATOM   1692  C  CE3  . TRP   A 1 107 ? 20.132  -7.800  36.618  1.00 30.90  ?  106 TRP   B CE3  1 
ATOM   1693  C  CZ2  . TRP   A 1 107 ? 21.155  -5.357  37.587  1.00 23.55  ?  106 TRP   B CZ2  1 
ATOM   1694  C  CZ3  . TRP   A 1 107 ? 21.443  -7.395  36.356  1.00 24.55  ?  106 TRP   B CZ3  1 
ATOM   1695  C  CH2  . TRP   A 1 107 ? 21.920  -6.190  36.819  1.00 25.94  ?  106 TRP   B CH2  1 
ATOM   1696  H  H    . TRP   A 1 107 ? 14.902  -9.279  36.725  1.00 31.37  ?  106 TRP   B H    1 
ATOM   1697  H  HA   . TRP   A 1 107 ? 15.791  -6.872  36.400  1.00 35.46  ?  106 TRP   B HA   1 
ATOM   1698  H  HB2  . TRP   A 1 107 ? 16.336  -8.199  38.331  1.00 31.28  ?  106 TRP   B HB2  1 
ATOM   1699  H  HB3  . TRP   A 1 107 ? 17.409  -8.959  37.440  1.00 31.28  ?  106 TRP   B HB3  1 
ATOM   1700  H  HD1  . TRP   A 1 107 ? 16.922  -5.701  39.006  1.00 33.67  ?  106 TRP   B HD1  1 
ATOM   1701  H  HE1  . TRP   A 1 107 ? 18.923  -4.376  38.982  1.00 38.48  ?  106 TRP   B HE1  1 
ATOM   1702  H  HE3  . TRP   A 1 107 ? 19.812  -8.608  36.288  1.00 37.08  ?  106 TRP   B HE3  1 
ATOM   1703  H  HZ2  . TRP   A 1 107 ? 21.496  -4.558  37.919  1.00 28.26  ?  106 TRP   B HZ2  1 
ATOM   1704  H  HZ3  . TRP   A 1 107 ? 22.003  -7.949  35.860  1.00 29.45  ?  106 TRP   B HZ3  1 
ATOM   1705  H  HH2  . TRP   A 1 107 ? 22.788  -5.935  36.603  1.00 31.13  ?  106 TRP   B HH2  1 
ATOM   1706  N  N    . ALA   A 1 108 ? 17.403  -6.746  34.514  1.00 24.47  ?  107 ALA   B N    1 
ATOM   1707  C  CA   . ALA   A 1 108 ? 18.511  -6.669  33.588  1.00 32.87  ?  107 ALA   B CA   1 
ATOM   1708  C  C    . ALA   A 1 108 ? 18.991  -5.230  33.605  1.00 31.42  ?  107 ALA   B C    1 
ATOM   1709  O  O    . ALA   A 1 108 ? 18.247  -4.310  33.916  1.00 27.52  ?  107 ALA   B O    1 
ATOM   1710  C  CB   . ALA   A 1 108 ? 18.094  -7.105  32.186  1.00 28.19  ?  107 ALA   B CB   1 
ATOM   1711  H  H    . ALA   A 1 108 ? 17.010  -5.992  34.647  1.00 29.36  ?  107 ALA   B H    1 
ATOM   1712  H  HA   . ALA   A 1 108 ? 19.238  -7.249  33.862  1.00 39.45  ?  107 ALA   B HA   1 
ATOM   1713  H  HB1  . ALA   A 1 108 ? 18.835  -6.960  31.576  1.00 33.83  ?  107 ALA   B HB1  1 
ATOM   1714  H  HB2  . ALA   A 1 108 ? 17.859  -8.045  32.204  1.00 33.83  ?  107 ALA   B HB2  1 
ATOM   1715  H  HB3  . ALA   A 1 108 ? 17.328  -6.578  31.906  1.00 33.83  ?  107 ALA   B HB3  1 
ATOM   1716  N  N    . ASP   A 1 109 ? 20.241  -5.035  33.262  1.00 28.83  ?  108 ASP   B N    1 
ATOM   1717  C  CA   . ASP   A 1 109 ? 20.730  -3.701  32.905  1.00 25.67  ?  108 ASP   B CA   1 
ATOM   1718  C  C    . ASP   A 1 109 ? 20.289  -2.607  33.883  1.00 27.94  ?  108 ASP   B C    1 
ATOM   1719  O  O    . ASP   A 1 109 ? 20.024  -1.470  33.497  1.00 27.04  ?  108 ASP   B O    1 
ATOM   1720  C  CB   . ASP   A 1 109 ? 20.307  -3.343  31.468  1.00 36.76  ?  108 ASP   B CB   1 
ATOM   1721  C  CG   . ASP   A 1 109 ? 20.635  -4.462  30.457  1.00 45.79  ?  108 ASP   B CG   1 
ATOM   1722  O  OD1  . ASP   A 1 109 ? 19.759  -4.819  29.637  1.00 41.51  ?  108 ASP   B OD1  1 
ATOM   1723  O  OD2  . ASP   A 1 109 ? 21.791  -4.978  30.465  1.00 40.88  -1 108 ASP   B OD2  1 
ATOM   1724  H  H    . ASP   A 1 109 ? 20.838  -5.653  33.225  1.00 34.60  ?  108 ASP   B H    1 
ATOM   1725  H  HA   . ASP   A 1 109 ? 21.698  -3.730  32.960  1.00 30.80  ?  108 ASP   B HA   1 
ATOM   1726  H  HB2  . ASP   A 1 109 ? 19.349  -3.192  31.448  1.00 44.12  ?  108 ASP   B HB2  1 
ATOM   1727  H  HB3  . ASP   A 1 109 ? 20.776  -2.541  31.190  1.00 44.12  ?  108 ASP   B HB3  1 
ATOM   1728  N  N    . ASN   A 1 110 ? 20.289  -2.931  35.182  1.00 30.22  ?  109 ASN   B N    1 
ATOM   1729  C  CA   . ASN   A 1 110 ? 19.924  -1.971  36.231  1.00 29.54  ?  109 ASN   B CA   1 
ATOM   1730  C  C    . ASN   A 1 110 ? 18.502  -1.421  36.034  1.00 30.97  ?  109 ASN   B C    1 
ATOM   1731  O  O    . ASN   A 1 110 ? 18.220  -0.254  36.320  1.00 27.47  ?  109 ASN   B O    1 
ATOM   1732  C  CB   . ASN   A 1 110 ? 20.940  -0.826  36.267  1.00 23.57  ?  109 ASN   B CB   1 
ATOM   1733  C  CG   . ASN   A 1 110 ? 22.130  -1.116  37.187  1.00 39.23  ?  109 ASN   B CG   1 
ATOM   1734  O  OD1  . ASN   A 1 110 ? 22.135  -2.110  37.911  1.00 36.32  ?  109 ASN   B OD1  1 
ATOM   1735  N  ND2  . ASN   A 1 110 ? 23.112  -0.217  37.193  1.00 42.46  ?  109 ASN   B ND2  1 
ATOM   1736  H  H    . ASN   A 1 110 ? 20.499  -3.709  35.483  1.00 36.26  ?  109 ASN   B H    1 
ATOM   1737  H  HA   . ASN   A 1 110 ? 19.931  -2.431  37.085  1.00 35.45  ?  109 ASN   B HA   1 
ATOM   1738  H  HB2  . ASN   A 1 110 ? 21.282  -0.679  35.371  1.00 28.28  ?  109 ASN   B HB2  1 
ATOM   1739  H  HB3  . ASN   A 1 110 ? 20.500  -0.024  36.589  1.00 28.28  ?  109 ASN   B HB3  1 
ATOM   1740  H  HD21 . ASN   A 1 110 ? 23.058  0.483   36.696  1.00 50.95  ?  109 ASN   B HD21 1 
ATOM   1741  H  HD22 . ASN   A 1 110 ? 23.802  -0.336  37.693  1.00 50.95  ?  109 ASN   B HD22 1 
ATOM   1742  N  N    . ASN   A 1 111 ? 17.583  -2.253  35.563  1.00 26.07  ?  110 ASN   B N    1 
ATOM   1743  C  CA   . ASN   A 1 111 ? 16.220  -1.791  35.349  1.00 25.95  ?  110 ASN   B CA   1 
ATOM   1744  C  C    . ASN   A 1 111 ? 15.309  -1.976  36.555  1.00 33.74  ?  110 ASN   B C    1 
ATOM   1745  O  O    . ASN   A 1 111 ? 14.080  -1.991  36.386  1.00 31.53  ?  110 ASN   B O    1 
ATOM   1746  C  CB   . ASN   A 1 111 ? 15.592  -2.510  34.162  1.00 28.92  ?  110 ASN   B CB   1 
ATOM   1747  C  CG   . ASN   A 1 111 ? 15.371  -3.963  34.446  1.00 24.76  ?  110 ASN   B CG   1 
ATOM   1748  O  OD1  . ASN   A 1 111 ? 15.588  -4.426  35.588  1.00 23.66  ?  110 ASN   B OD1  1 
ATOM   1749  N  ND2  . ASN   A 1 111 ? 14.999  -4.730  33.401  1.00 30.87  ?  110 ASN   B ND2  1 
ATOM   1750  H  H    . ASN   A 1 111 ? 17.723  -3.078  35.363  1.00 31.29  ?  110 ASN   B H    1 
ATOM   1751  H  HA   . ASN   A 1 111 ? 16.280  -0.842  35.156  1.00 31.14  ?  110 ASN   B HA   1 
ATOM   1752  H  HB2  . ASN   A 1 111 ? 14.734  -2.105  33.961  1.00 34.70  ?  110 ASN   B HB2  1 
ATOM   1753  H  HB3  . ASN   A 1 111 ? 16.181  -2.436  33.395  1.00 34.70  ?  110 ASN   B HB3  1 
ATOM   1754  H  HD21 . ASN   A 1 111 ? 14.859  -5.571  33.512  1.00 37.04  ?  110 ASN   B HD21 1 
ATOM   1755  H  HD22 . ASN   A 1 111 ? 14.901  -4.377  32.623  1.00 37.04  ?  110 ASN   B HD22 1 
ATOM   1756  N  N    . SER   A 1 112 ? 15.850  -2.108  37.767  1.00 24.46  ?  111 SER   B N    1 
ATOM   1757  C  CA   . SER   A 1 112 ? 14.955  -2.258  38.915  1.00 29.85  ?  111 SER   B CA   1 
ATOM   1758  C  C    . SER   A 1 112 ? 14.065  -1.013  39.096  1.00 35.41  ?  111 SER   B C    1 
ATOM   1759  O  O    . SER   A 1 112 ? 12.875  -1.110  39.458  1.00 29.17  ?  111 SER   B O    1 
ATOM   1760  C  CB   . SER   A 1 112 ? 15.756  -2.517  40.185  1.00 31.13  ?  111 SER   B CB   1 
ATOM   1761  O  OG   . SER   A 1 112 ? 16.358  -1.316  40.584  1.00 29.46  ?  111 SER   B OG   1 
ATOM   1762  H  H    . SER   A 1 112 ? 16.691  -2.113  37.944  1.00 29.35  ?  111 SER   B H    1 
ATOM   1763  H  HA   . SER   A 1 112 ? 14.383  -3.026  38.758  1.00 35.81  ?  111 SER   B HA   1 
ATOM   1764  H  HB2  . SER   A 1 112 ? 15.163  -2.832  40.885  1.00 37.35  ?  111 SER   B HB2  1 
ATOM   1765  H  HB3  . SER   A 1 112 ? 16.441  -3.181  40.007  1.00 37.35  ?  111 SER   B HB3  1 
ATOM   1766  H  HG   . SER   A 1 112 ? 17.103  -1.472  40.939  1.00 35.36  ?  111 SER   B HG   1 
ATOM   1767  N  N    . TYR   A 1 113 ? 14.638  0.173   38.891  1.00 29.42  ?  112 TYR   B N    1 
ATOM   1768  C  CA   . TYR   A 1 113 ? 13.824  1.361   39.061  1.00 27.99  ?  112 TYR   B CA   1 
ATOM   1769  C  C    . TYR   A 1 113 ? 12.682  1.404   38.032  1.00 32.34  ?  112 TYR   B C    1 
ATOM   1770  O  O    . TYR   A 1 113 ? 11.574  1.885   38.332  1.00 28.01  ?  112 TYR   B O    1 
ATOM   1771  C  CB   . TYR   A 1 113 ? 14.661  2.611   38.962  1.00 24.66  ?  112 TYR   B CB   1 
ATOM   1772  C  CG   . TYR   A 1 113 ? 15.072  2.997   37.571  1.00 25.68  ?  112 TYR   B CG   1 
ATOM   1773  C  CD1  . TYR   A 1 113 ? 16.032  2.270   36.893  1.00 24.18  ?  112 TYR   B CD1  1 
ATOM   1774  C  CD2  . TYR   A 1 113 ? 14.570  4.127   36.966  1.00 30.62  ?  112 TYR   B CD2  1 
ATOM   1775  C  CE1  . TYR   A 1 113 ? 16.448  2.629   35.639  1.00 25.55  ?  112 TYR   B CE1  1 
ATOM   1776  C  CE2  . TYR   A 1 113 ? 15.009  4.512   35.698  1.00 31.45  ?  112 TYR   B CE2  1 
ATOM   1777  C  CZ   . TYR   A 1 113 ? 15.951  3.756   35.055  1.00 22.82  ?  112 TYR   B CZ   1 
ATOM   1778  O  OH   . TYR   A 1 113 ? 16.379  4.086   33.768  1.00 29.89  ?  112 TYR   B OH   1 
ATOM   1779  H  H    . TYR   A 1 113 ? 15.457  0.306   38.665  1.00 35.30  ?  112 TYR   B H    1 
ATOM   1780  H  HA   . TYR   A 1 113 ? 13.439  1.341   39.951  1.00 33.59  ?  112 TYR   B HA   1 
ATOM   1781  H  HB2  . TYR   A 1 113 ? 14.152  3.350   39.329  1.00 29.59  ?  112 TYR   B HB2  1 
ATOM   1782  H  HB3  . TYR   A 1 113 ? 15.472  2.478   39.477  1.00 29.59  ?  112 TYR   B HB3  1 
ATOM   1783  H  HD1  . TYR   A 1 113 ? 16.404  1.520   37.298  1.00 29.01  ?  112 TYR   B HD1  1 
ATOM   1784  H  HD2  . TYR   A 1 113 ? 13.931  4.640   37.407  1.00 36.75  ?  112 TYR   B HD2  1 
ATOM   1785  H  HE1  . TYR   A 1 113 ? 17.069  2.105   35.186  1.00 30.66  ?  112 TYR   B HE1  1 
ATOM   1786  H  HE2  . TYR   A 1 113 ? 14.664  5.275   35.293  1.00 37.74  ?  112 TYR   B HE2  1 
ATOM   1787  H  HH   . TYR   A 1 113 ? 16.173  4.882   33.592  1.00 35.87  ?  112 TYR   B HH   1 
ATOM   1788  N  N    . LEU   A 1 114 ? 12.913  0.891   36.829  1.00 29.58  ?  113 LEU   B N    1 
ATOM   1789  C  CA   . LEU   A 1 114 ? 11.845  0.925   35.833  1.00 27.71  ?  113 LEU   B CA   1 
ATOM   1790  C  C    . LEU   A 1 114 ? 10.710  -0.004  36.236  1.00 33.79  ?  113 LEU   B C    1 
ATOM   1791  O  O    . LEU   A 1 114 ? 9.534   0.384   36.220  1.00 29.22  ?  113 LEU   B O    1 
ATOM   1792  C  CB   . LEU   A 1 114 ? 12.390  0.559   34.463  1.00 33.95  ?  113 LEU   B CB   1 
ATOM   1793  C  CG   . LEU   A 1 114 ? 13.120  1.706   33.746  1.00 33.72  ?  113 LEU   B CG   1 
ATOM   1794  C  CD1  . LEU   A 1 114 ? 13.782  1.196   32.497  1.00 36.61  ?  113 LEU   B CD1  1 
ATOM   1795  C  CD2  . LEU   A 1 114 ? 12.087  2.814   33.420  1.00 31.35  ?  113 LEU   B CD2  1 
ATOM   1796  H  H    . LEU   A 1 114 ? 13.650  0.531   36.571  1.00 35.49  ?  113 LEU   B H    1 
ATOM   1797  H  HA   . LEU   A 1 114 ? 11.494  1.828   35.775  1.00 33.25  ?  113 LEU   B HA   1 
ATOM   1798  H  HB2  . LEU   A 1 114 ? 13.020  -0.172  34.565  1.00 40.75  ?  113 LEU   B HB2  1 
ATOM   1799  H  HB3  . LEU   A 1 114 ? 11.650  0.283   33.899  1.00 40.75  ?  113 LEU   B HB3  1 
ATOM   1800  H  HG   . LEU   A 1 114 ? 13.816  2.080   34.309  1.00 40.47  ?  113 LEU   B HG   1 
ATOM   1801  H  HD11 . LEU   A 1 114 ? 14.421  1.856   32.187  1.00 43.94  ?  113 LEU   B HD11 1 
ATOM   1802  H  HD12 . LEU   A 1 114 ? 14.237  0.364   32.699  1.00 43.94  ?  113 LEU   B HD12 1 
ATOM   1803  H  HD13 . LEU   A 1 114 ? 13.104  1.047   31.820  1.00 43.94  ?  113 LEU   B HD13 1 
ATOM   1804  H  HD21 . LEU   A 1 114 ? 12.468  3.417   32.762  1.00 37.61  ?  113 LEU   B HD21 1 
ATOM   1805  H  HD22 . LEU   A 1 114 ? 11.284  2.402   33.065  1.00 37.61  ?  113 LEU   B HD22 1 
ATOM   1806  H  HD23 . LEU   A 1 114 ? 11.878  3.301   34.233  1.00 37.61  ?  113 LEU   B HD23 1 
ATOM   1807  N  N    . ALA   A 1 115 ? 11.051  -1.225  36.632  1.00 28.02  ?  114 ALA   B N    1 
ATOM   1808  C  CA   . ALA   A 1 115 ? 10.057  -2.138  37.171  1.00 34.25  ?  114 ALA   B CA   1 
ATOM   1809  C  C    . ALA   A 1 115 ? 9.227   -1.467  38.262  1.00 30.72  ?  114 ALA   B C    1 
ATOM   1810  O  O    . ALA   A 1 115 ? 8.001   -1.428  38.177  1.00 33.78  ?  114 ALA   B O    1 
ATOM   1811  C  CB   . ALA   A 1 115 ? 10.758  -3.394  37.682  1.00 26.90  ?  114 ALA   B CB   1 
ATOM   1812  H  H    . ALA   A 1 115 ? 11.848  -1.546  36.598  1.00 33.62  ?  114 ALA   B H    1 
ATOM   1813  H  HA   . ALA   A 1 115 ? 9.442   -2.405  36.470  1.00 41.09  ?  114 ALA   B HA   1 
ATOM   1814  H  HB1  . ALA   A 1 115 ? 10.096  -3.995  38.057  1.00 32.28  ?  114 ALA   B HB1  1 
ATOM   1815  H  HB2  . ALA   A 1 115 ? 11.214  -3.824  36.941  1.00 32.28  ?  114 ALA   B HB2  1 
ATOM   1816  H  HB3  . ALA   A 1 115 ? 11.400  -3.142  38.364  1.00 32.28  ?  114 ALA   B HB3  1 
ATOM   1817  N  N    . THR   A 1 116 ? 9.875   -0.890  39.276  1.00 31.37  ?  115 THR   B N    1 
ATOM   1818  C  CA   . THR   A 1 116 ? 9.123   -0.276  40.368  1.00 26.60  ?  115 THR   B CA   1 
ATOM   1819  C  C    . THR   A 1 116 ? 8.190   0.798   39.845  1.00 31.51  ?  115 THR   B C    1 
ATOM   1820  O  O    . THR   A 1 116 ? 7.061   0.942   40.341  1.00 30.77  ?  115 THR   B O    1 
ATOM   1821  C  CB   . THR   A 1 116 ? 10.075  0.307   41.408  1.00 35.06  ?  115 THR   B CB   1 
ATOM   1822  O  OG1  . THR   A 1 116 ? 10.874  -0.755  41.941  1.00 35.31  ?  115 THR   B OG1  1 
ATOM   1823  C  CG2  . THR   A 1 116 ? 9.276   0.951   42.512  1.00 31.29  ?  115 THR   B CG2  1 
ATOM   1824  H  H    . THR   A 1 116 ? 10.730  -0.842  39.353  1.00 37.64  ?  115 THR   B H    1 
ATOM   1825  H  HA   . THR   A 1 116 ? 8.591   -0.961  40.803  1.00 31.92  ?  115 THR   B HA   1 
ATOM   1826  H  HB   . THR   A 1 116 ? 10.653  0.979   41.014  1.00 42.07  ?  115 THR   B HB   1 
ATOM   1827  H  HG1  . THR   A 1 116 ? 11.005  -0.631  42.761  1.00 42.37  ?  115 THR   B HG1  1 
ATOM   1828  H  HG21 . THR   A 1 116 ? 9.864   1.206   43.241  1.00 37.55  ?  115 THR   B HG21 1 
ATOM   1829  H  HG22 . THR   A 1 116 ? 8.828   1.744   42.178  1.00 37.55  ?  115 THR   B HG22 1 
ATOM   1830  H  HG23 . THR   A 1 116 ? 8.611   0.330   42.846  1.00 37.55  ?  115 THR   B HG23 1 
ATOM   1831  N  N    . ALA   A 1 117 ? 8.651   1.583   38.859  1.00 26.34  ?  116 ALA   B N    1 
ATOM   1832  C  CA   . ALA   A 1 117 ? 7.780   2.604   38.281  1.00 30.96  ?  116 ALA   B CA   1 
ATOM   1833  C  C    . ALA   A 1 117 ? 6.588   1.949   37.588  1.00 29.76  ?  116 ALA   B C    1 
ATOM   1834  O  O    . ALA   A 1 117 ? 5.422   2.332   37.798  1.00 30.53  ?  116 ALA   B O    1 
ATOM   1835  C  CB   . ALA   A 1 117 ? 8.569   3.484   37.312  1.00 28.66  ?  116 ALA   B CB   1 
ATOM   1836  H  H    . ALA   A 1 117 ? 9.441   1.543   38.521  1.00 31.61  ?  116 ALA   B H    1 
ATOM   1837  H  HA   . ALA   A 1 117 ? 7.446   3.180   38.986  1.00 37.16  ?  116 ALA   B HA   1 
ATOM   1838  H  HB1  . ALA   A 1 117 ? 7.968   4.133   36.914  1.00 34.39  ?  116 ALA   B HB1  1 
ATOM   1839  H  HB2  . ALA   A 1 117 ? 9.272   3.940   37.800  1.00 34.39  ?  116 ALA   B HB2  1 
ATOM   1840  H  HB3  . ALA   A 1 117 ? 8.956   2.924   36.621  1.00 34.39  ?  116 ALA   B HB3  1 
ATOM   1841  N  N    . LEU   A 1 118 ? 6.908   0.976   36.781  1.00 28.88  ?  117 LEU   B N    1 
ATOM   1842  C  CA   . LEU   A 1 118 ? 5.906   0.259   36.069  1.00 37.90  ?  117 LEU   B CA   1 
ATOM   1843  C  C    . LEU   A 1 118 ? 4.889   -0.305  37.047  1.00 30.41  ?  117 LEU   B C    1 
ATOM   1844  O  O    . LEU   A 1 118 ? 3.731   -0.101  36.814  1.00 26.81  ?  117 LEU   B O    1 
ATOM   1845  C  CB   . LEU   A 1 118 ? 6.510   -0.795  35.189  1.00 26.15  ?  117 LEU   B CB   1 
ATOM   1846  C  CG   . LEU   A 1 118 ? 5.547   -1.595  34.364  1.00 30.32  ?  117 LEU   B CG   1 
ATOM   1847  C  CD1  . LEU   A 1 118 ? 4.711   -0.750  33.433  1.00 34.93  ?  117 LEU   B CD1  1 
ATOM   1848  C  CD2  . LEU   A 1 118 ? 6.308   -2.640  33.601  1.00 24.34  ?  117 LEU   B CD2  1 
ATOM   1849  H  H    . LEU   A 1 118 ? 7.711   0.709   36.630  1.00 34.66  ?  117 LEU   B H    1 
ATOM   1850  H  HA   . LEU   A 1 118 ? 5.432   0.888   35.486  1.00 45.48  ?  117 LEU   B HA   1 
ATOM   1851  H  HB2  . LEU   A 1 118 ? 7.126   -0.364  34.576  1.00 31.38  ?  117 LEU   B HB2  1 
ATOM   1852  H  HB3  . LEU   A 1 118 ? 6.997   -1.418  35.751  1.00 31.38  ?  117 LEU   B HB3  1 
ATOM   1853  H  HG   . LEU   A 1 118 ? 4.941   -2.057  34.963  1.00 36.39  ?  117 LEU   B HG   1 
ATOM   1854  H  HD11 . LEU   A 1 118 ? 4.285   -1.325  32.795  1.00 41.91  ?  117 LEU   B HD11 1 
ATOM   1855  H  HD12 . LEU   A 1 118 ? 4.048   -0.281  33.946  1.00 41.91  ?  117 LEU   B HD12 1 
ATOM   1856  H  HD13 . LEU   A 1 118 ? 5.282   -0.124  32.982  1.00 41.91  ?  117 LEU   B HD13 1 
ATOM   1857  H  HD21 . LEU   A 1 118 ? 5.854   -2.815  32.774  1.00 29.21  ?  117 LEU   B HD21 1 
ATOM   1858  H  HD22 . LEU   A 1 118 ? 7.194   -2.318  33.427  1.00 29.21  ?  117 LEU   B HD22 1 
ATOM   1859  H  HD23 . LEU   A 1 118 ? 6.348   -3.443  34.127  1.00 29.21  ?  117 LEU   B HD23 1 
ATOM   1860  N  N    . LEU   A 1 119 ? 5.229   -1.137  38.017  1.00 29.55  ?  118 LEU   B N    1 
ATOM   1861  C  CA   . LEU   A 1 119 ? 4.338   -1.661  39.048  1.00 36.90  ?  118 LEU   B CA   1 
ATOM   1862  C  C    . LEU   A 1 119 ? 3.488   -0.556  39.689  1.00 30.80  ?  118 LEU   B C    1 
ATOM   1863  O  O    . LEU   A 1 119 ? 2.284   -0.704  39.893  1.00 34.67  ?  118 LEU   B O    1 
ATOM   1864  C  CB   . LEU   A 1 119 ? 5.126   -2.361  40.151  1.00 31.64  ?  118 LEU   B CB   1 
ATOM   1865  C  CG   . LEU   A 1 119 ? 5.684   -3.759  40.091  1.00 38.79  ?  118 LEU   B CG   1 
ATOM   1866  C  CD1  . LEU   A 1 119 ? 4.918   -4.738  39.280  1.00 38.84  ?  118 LEU   B CD1  1 
ATOM   1867  C  CD2  . LEU   A 1 119 ? 7.121   -3.694  39.582  1.00 46.00  ?  118 LEU   B CD2  1 
ATOM   1868  H  H    . LEU   A 1 119 ? 6.057   -1.347  38.120  1.00 35.46  ?  118 LEU   B H    1 
ATOM   1869  H  HA   . LEU   A 1 119 ? 3.758   -2.305  38.612  1.00 44.28  ?  118 LEU   B HA   1 
ATOM   1870  H  HB2  . LEU   A 1 119 ? 5.898   -1.798  40.320  1.00 37.97  ?  118 LEU   B HB2  1 
ATOM   1871  H  HB3  . LEU   A 1 119 ? 4.543   -2.366  40.926  1.00 37.97  ?  118 LEU   B HB3  1 
ATOM   1872  H  HG   . LEU   A 1 119 ? 5.629   -4.105  40.995  1.00 46.54  ?  118 LEU   B HG   1 
ATOM   1873  H  HD11 . LEU   A 1 119 ? 5.413   -5.571  39.240  1.00 46.61  ?  118 LEU   B HD11 1 
ATOM   1874  H  HD12 . LEU   A 1 119 ? 4.055   -4.887  39.698  1.00 46.61  ?  118 LEU   B HD12 1 
ATOM   1875  H  HD13 . LEU   A 1 119 ? 4.796   -4.382  38.386  1.00 46.61  ?  118 LEU   B HD13 1 
ATOM   1876  H  HD21 . LEU   A 1 119 ? 7.469   -4.596  39.501  1.00 55.20  ?  118 LEU   B HD21 1 
ATOM   1877  H  HD22 . LEU   A 1 119 ? 7.131   -3.256  38.717  1.00 55.20  ?  118 LEU   B HD22 1 
ATOM   1878  H  HD23 . LEU   A 1 119 ? 7.657   -3.189  40.214  1.00 55.20  ?  118 LEU   B HD23 1 
ATOM   1879  N  N    . THR   A 1 120 ? 4.109   0.563   40.028  1.00 32.87  ?  119 THR   B N    1 
ATOM   1880  C  CA   . THR   A 1 120 ? 3.353   1.648   40.640  1.00 35.67  ?  119 THR   B CA   1 
ATOM   1881  C  C    . THR   A 1 120 ? 2.317   2.212   39.684  1.00 28.48  ?  119 THR   B C    1 
ATOM   1882  O  O    . THR   A 1 120 ? 1.215   2.564   40.106  1.00 34.79  ?  119 THR   B O    1 
ATOM   1883  C  CB   . THR   A 1 120 ? 4.319   2.741   41.093  1.00 27.66  ?  119 THR   B CB   1 
ATOM   1884  O  OG1  . THR   A 1 120 ? 5.152   2.159   42.087  1.00 28.90  ?  119 THR   B OG1  1 
ATOM   1885  C  CG2  . THR   A 1 120 ? 3.605   3.917   41.701  1.00 32.08  ?  119 THR   B CG2  1 
ATOM   1886  H  H    . THR   A 1 120 ? 4.947   0.719   39.917  1.00 39.44  ?  119 THR   B H    1 
ATOM   1887  H  HA   . THR   A 1 120 ? 2.881   1.310   41.417  1.00 42.81  ?  119 THR   B HA   1 
ATOM   1888  H  HB   . THR   A 1 120 ? 4.821   3.076   40.333  1.00 33.19  ?  119 THR   B HB   1 
ATOM   1889  H  HG1  . THR   A 1 120 ? 5.517   2.762   42.544  1.00 34.68  ?  119 THR   B HG1  1 
ATOM   1890  H  HG21 . THR   A 1 120 ? 4.242   4.500   42.143  1.00 38.50  ?  119 THR   B HG21 1 
ATOM   1891  H  HG22 . THR   A 1 120 ? 3.146   4.420   41.010  1.00 38.50  ?  119 THR   B HG22 1 
ATOM   1892  H  HG23 . THR   A 1 120 ? 2.955   3.611   42.352  1.00 38.50  ?  119 THR   B HG23 1 
ATOM   1893  N  N    . LEU   A 1 121 ? 2.678   2.366   38.399  1.00 31.65  ?  120 LEU   B N    1 
ATOM   1894  C  CA   . LEU   A 1 121 ? 1.785   3.032   37.467  1.00 34.86  ?  120 LEU   B CA   1 
ATOM   1895  C  C    . LEU   A 1 121 ? 0.535   2.201   37.299  1.00 39.30  ?  120 LEU   B C    1 
ATOM   1896  O  O    . LEU   A 1 121 ? -0.535  2.740   37.069  1.00 38.95  ?  120 LEU   B O    1 
ATOM   1897  C  CB   . LEU   A 1 121 ? 2.444   3.258   36.115  1.00 31.07  ?  120 LEU   B CB   1 
ATOM   1898  C  CG   . LEU   A 1 121 ? 3.386   4.412   36.057  1.00 31.15  ?  120 LEU   B CG   1 
ATOM   1899  C  CD1  . LEU   A 1 121 ? 4.020   4.515   34.674  1.00 47.12  ?  120 LEU   B CD1  1 
ATOM   1900  C  CD2  . LEU   A 1 121 ? 2.783   5.730   36.333  1.00 31.91  ?  120 LEU   B CD2  1 
ATOM   1901  H  H    . LEU   A 1 121 ? 3.421   2.097   38.058  1.00 37.98  ?  120 LEU   B H    1 
ATOM   1902  H  HA   . LEU   A 1 121 ? 1.565   3.912   37.810  1.00 41.84  ?  120 LEU   B HA   1 
ATOM   1903  H  HB2  . LEU   A 1 121 ? 2.945   2.461   35.881  1.00 37.29  ?  120 LEU   B HB2  1 
ATOM   1904  H  HB3  . LEU   A 1 121 ? 1.748   3.417   35.458  1.00 37.29  ?  120 LEU   B HB3  1 
ATOM   1905  H  HG   . LEU   A 1 121 ? 4.034   4.229   36.756  1.00 37.38  ?  120 LEU   B HG   1 
ATOM   1906  H  HD11 . LEU   A 1 121 ? 4.632   5.267   34.663  1.00 56.54  ?  120 LEU   B HD11 1 
ATOM   1907  H  HD12 . LEU   A 1 121 ? 4.501   3.694   34.486  1.00 56.54  ?  120 LEU   B HD12 1 
ATOM   1908  H  HD13 . LEU   A 1 121 ? 3.320   4.647   34.015  1.00 56.54  ?  120 LEU   B HD13 1 
ATOM   1909  H  HD21 . LEU   A 1 121 ? 3.468   6.412   36.264  1.00 38.29  ?  120 LEU   B HD21 1 
ATOM   1910  H  HD22 . LEU   A 1 121 ? 2.081   5.898   35.685  1.00 38.29  ?  120 LEU   B HD22 1 
ATOM   1911  H  HD23 . LEU   A 1 121 ? 2.410   5.725   37.229  1.00 38.29  ?  120 LEU   B HD23 1 
ATOM   1912  N  N    . GLN   A 1 122 ? 0.643   0.894   37.478  1.00 38.39  ?  121 GLN   B N    1 
ATOM   1913  C  CA   . GLN   A 1 122 ? -0.516  0.044   37.365  1.00 33.39  ?  121 GLN   B CA   1 
ATOM   1914  C  C    . GLN   A 1 122 ? -1.427  0.126   38.577  1.00 43.41  ?  121 GLN   B C    1 
ATOM   1915  O  O    . GLN   A 1 122 ? -2.513  -0.468  38.548  1.00 34.66  ?  121 GLN   B O    1 
ATOM   1916  C  CB   . GLN   A 1 122 ? -0.071  -1.386  37.174  1.00 29.63  ?  121 GLN   B CB   1 
ATOM   1917  C  CG   . GLN   A 1 122 ? 0.347   -1.702  35.750  1.00 27.04  ?  121 GLN   B CG   1 
ATOM   1918  C  CD   . GLN   A 1 122 ? 1.250   -2.888  35.711  1.00 33.58  ?  121 GLN   B CD   1 
ATOM   1919  O  OE1  . GLN   A 1 122 ? 0.801   -3.995  35.417  1.00 27.88  ?  121 GLN   B OE1  1 
ATOM   1920  N  NE2  . GLN   A 1 122 ? 2.523   -2.694  36.106  1.00 32.88  ?  121 GLN   B NE2  1 
ATOM   1921  H  H    . GLN   A 1 122 ? 1.374   0.482   37.665  1.00 46.07  ?  121 GLN   B H    1 
ATOM   1922  H  HA   . GLN   A 1 122 ? -1.029  0.318   36.588  1.00 40.07  ?  121 GLN   B HA   1 
ATOM   1923  H  HB2  . GLN   A 1 122 ? 0.688   -1.557  37.753  1.00 35.56  ?  121 GLN   B HB2  1 
ATOM   1924  H  HB3  . GLN   A 1 122 ? -0.805  -1.976  37.406  1.00 35.56  ?  121 GLN   B HB3  1 
ATOM   1925  H  HG2  . GLN   A 1 122 ? -0.440  -1.896  35.217  1.00 32.45  ?  121 GLN   B HG2  1 
ATOM   1926  H  HG3  . GLN   A 1 122 ? 0.821   -0.942  35.377  1.00 32.45  ?  121 GLN   B HG3  1 
ATOM   1927  H  HE21 . GLN   A 1 122 ? 2.779   -1.915  36.364  1.00 39.45  ?  121 GLN   B HE21 1 
ATOM   1928  H  HE22 . GLN   A 1 122 ? 3.080   -3.350  36.100  1.00 39.45  ?  121 GLN   B HE22 1 
ATOM   1929  N  N    . GLN   A 1 123 ? -1.050  0.868   39.619  1.00 37.33  ?  122 GLN   B N    1 
ATOM   1930  C  CA   . GLN   A 1 123 ? -1.832  0.884   40.850  1.00 37.01  ?  122 GLN   B CA   1 
ATOM   1931  C  C    . GLN   A 1 123 ? -2.468  2.236   41.151  1.00 38.20  ?  122 GLN   B C    1 
ATOM   1932  O  O    . GLN   A 1 123 ? -3.212  2.360   42.132  1.00 41.96  ?  122 GLN   B O    1 
ATOM   1933  C  CB   . GLN   A 1 123 ? -0.963  0.422   42.030  1.00 30.81  ?  122 GLN   B CB   1 
ATOM   1934  C  CG   . GLN   A 1 123 ? -0.935  -1.079  42.071  1.00 31.52  ?  122 GLN   B CG   1 
ATOM   1935  C  CD   . GLN   A 1 123 ? 0.098   -1.616  43.010  1.00 40.31  ?  122 GLN   B CD   1 
ATOM   1936  O  OE1  . GLN   A 1 123 ? -0.206  -1.981  44.116  1.00 36.24  ?  122 GLN   B OE1  1 
ATOM   1937  N  NE2  . GLN   A 1 123 ? 1.329   -1.676  42.563  1.00 40.34  ?  122 GLN   B NE2  1 
ATOM   1938  H  H    . GLN   A 1 123 ? -0.348  1.365   39.635  1.00 44.80  ?  122 GLN   B H    1 
ATOM   1939  H  HA   . GLN   A 1 123 ? -2.562  0.251   40.759  1.00 44.41  ?  122 GLN   B HA   1 
ATOM   1940  H  HB2  . GLN   A 1 123 ? -0.057  0.750   41.918  1.00 36.97  ?  122 GLN   B HB2  1 
ATOM   1941  H  HB3  . GLN   A 1 123 ? -1.335  0.753   42.862  1.00 36.97  ?  122 GLN   B HB3  1 
ATOM   1942  H  HG2  . GLN   A 1 123 ? -1.802  -1.403  42.363  1.00 37.82  ?  122 GLN   B HG2  1 
ATOM   1943  H  HG3  . GLN   A 1 123 ? -0.737  -1.416  41.183  1.00 37.82  ?  122 GLN   B HG3  1 
ATOM   1944  H  HE21 . GLN   A 1 123 ? 1.510   -1.413  41.764  1.00 48.41  ?  122 GLN   B HE21 1 
ATOM   1945  H  HE22 . GLN   A 1 123 ? 1.956   -1.978  43.069  1.00 48.41  ?  122 GLN   B HE22 1 
ATOM   1946  N  N    . ILE   A 1 124 ? -2.213  3.244   40.336  1.00 39.79  ?  123 ILE   B N    1 
ATOM   1947  C  CA   . ILE   A 1 124 ? -2.731  4.579   40.557  1.00 37.02  ?  123 ILE   B CA   1 
ATOM   1948  C  C    . ILE   A 1 124 ? -3.419  5.009   39.271  1.00 38.27  ?  123 ILE   B C    1 
ATOM   1949  O  O    . ILE   A 1 124 ? -3.177  4.457   38.186  1.00 36.03  ?  123 ILE   B O    1 
ATOM   1950  C  CB   . ILE   A 1 124 ? -1.601  5.565   40.960  1.00 38.59  ?  123 ILE   B CB   1 
ATOM   1951  C  CG1  . ILE   A 1 124 ? -0.577  5.646   39.831  1.00 43.90  ?  123 ILE   B CG1  1 
ATOM   1952  C  CG2  . ILE   A 1 124 ? -0.960  5.122   42.259  1.00 32.99  ?  123 ILE   B CG2  1 
ATOM   1953  C  CD1  . ILE   A 1 124 ? 0.618   6.546   40.095  1.00 37.72  ?  123 ILE   B CD1  1 
ATOM   1954  H  H    . ILE   A 1 124 ? -1.730  3.177   39.628  1.00 47.75  ?  123 ILE   B H    1 
ATOM   1955  H  HA   . ILE   A 1 124 ? -3.388  4.588   41.270  1.00 44.42  ?  123 ILE   B HA   1 
ATOM   1956  H  HB   . ILE   A 1 124 ? -1.975  6.449   41.101  1.00 46.31  ?  123 ILE   B HB   1 
ATOM   1957  H  HG12 . ILE   A 1 124 ? -0.235  4.753   39.666  1.00 52.68  ?  123 ILE   B HG12 1 
ATOM   1958  H  HG13 . ILE   A 1 124 ? -1.022  5.982   39.038  1.00 52.68  ?  123 ILE   B HG13 1 
ATOM   1959  H  HG21 . ILE   A 1 124 ? -0.423  5.849   42.610  1.00 39.59  ?  123 ILE   B HG21 1 
ATOM   1960  H  HG22 . ILE   A 1 124 ? -1.657  4.890   42.892  1.00 39.59  ?  123 ILE   B HG22 1 
ATOM   1961  H  HG23 . ILE   A 1 124 ? -0.399  4.350   42.087  1.00 39.59  ?  123 ILE   B HG23 1 
ATOM   1962  H  HD11 . ILE   A 1 124 ? 1.038   6.769   39.250  1.00 45.26  ?  123 ILE   B HD11 1 
ATOM   1963  H  HD12 . ILE   A 1 124 ? 0.314   7.354   40.536  1.00 45.26  ?  123 ILE   B HD12 1 
ATOM   1964  H  HD13 . ILE   A 1 124 ? 1.248   6.076   40.664  1.00 45.26  ?  123 ILE   B HD13 1 
ATOM   1965  N  N    . GLU   A 1 125 ? -4.248  6.040   39.409  1.00 43.16  ?  124 GLU   B N    1 
ATOM   1966  C  CA   . GLU   A 1 125 ? -5.083  6.558   38.332  1.00 50.39  ?  124 GLU   B CA   1 
ATOM   1967  C  C    . GLU   A 1 125 ? -4.341  7.684   37.633  1.00 44.66  ?  124 GLU   B C    1 
ATOM   1968  O  O    . GLU   A 1 125 ? -4.233  8.782   38.189  1.00 46.68  ?  124 GLU   B O    1 
ATOM   1969  C  CB   . GLU   A 1 125 ? -6.390  7.127   38.876  1.00 48.77  ?  124 GLU   B CB   1 
ATOM   1970  C  CG   . GLU   A 1 125 ? -7.613  6.270   38.884  1.00 65.85  ?  124 GLU   B CG   1 
ATOM   1971  C  CD   . GLU   A 1 125 ? -8.835  7.060   39.434  1.00 67.28  ?  124 GLU   B CD   1 
ATOM   1972  O  OE1  . GLU   A 1 125 ? -9.480  6.587   40.415  1.00 60.48  ?  124 GLU   B OE1  1 
ATOM   1973  O  OE2  . GLU   A 1 125 ? -9.126  8.156   38.879  1.00 65.90  -1 124 GLU   B OE2  1 
ATOM   1974  H  H    . GLU   A 1 125 ? -4.349  6.471   40.147  1.00 51.79  ?  124 GLU   B H    1 
ATOM   1975  H  HA   . GLU   A 1 125 ? -5.262  5.830   37.716  1.00 60.47  ?  124 GLU   B HA   1 
ATOM   1976  H  HB2  . GLU   A 1 125 ? -6.232  7.385   39.797  1.00 58.52  ?  124 GLU   B HB2  1 
ATOM   1977  H  HB3  . GLU   A 1 125 ? -6.609  7.908   38.345  1.00 58.52  ?  124 GLU   B HB3  1 
ATOM   1978  H  HG2  . GLU   A 1 125 ? -7.813  5.983   37.980  1.00 79.02  ?  124 GLU   B HG2  1 
ATOM   1979  H  HG3  . GLU   A 1 125 ? -7.463  5.498   39.453  1.00 79.02  ?  124 GLU   B HG3  1 
ATOM   1980  N  N    . LEU   A 1 126 ? -3.904  7.454   36.400  1.00 46.09  ?  125 LEU   B N    1 
ATOM   1981  C  CA   . LEU   A 1 126 ? -3.104  8.446   35.696  1.00 55.80  ?  125 LEU   B CA   1 
ATOM   1982  C  C    . LEU   A 1 126 ? -3.399  8.372   34.205  1.00 48.62  ?  125 LEU   B C    1 
ATOM   1983  O  O    . LEU   A 1 126 ? -3.486  7.281   33.639  1.00 45.42  ?  125 LEU   B O    1 
ATOM   1984  C  CB   . LEU   A 1 126 ? -1.616  8.220   35.970  1.00 48.88  ?  125 LEU   B CB   1 
ATOM   1985  C  CG   . LEU   A 1 126 ? -0.671  9.315   35.476  1.00 50.53  ?  125 LEU   B CG   1 
ATOM   1986  C  CD1  . LEU   A 1 126 ? -0.794  10.565  36.307  1.00 66.69  ?  125 LEU   B CD1  1 
ATOM   1987  C  CD2  . LEU   A 1 126 ? 0.760   8.813   35.470  1.00 46.72  ?  125 LEU   B CD2  1 
ATOM   1988  H  H    . LEU   A 1 126 ? -4.056  6.735   35.953  1.00 55.31  ?  125 LEU   B H    1 
ATOM   1989  H  HA   . LEU   A 1 126 ? -3.343  9.340   35.989  1.00 66.95  ?  125 LEU   B HA   1 
ATOM   1990  H  HB2  . LEU   A 1 126 ? -1.493  8.145   36.929  1.00 58.66  ?  125 LEU   B HB2  1 
ATOM   1991  H  HB3  . LEU   A 1 126 ? -1.351  7.394   35.536  1.00 58.66  ?  125 LEU   B HB3  1 
ATOM   1992  H  HG   . LEU   A 1 126 ? -0.917  9.548   34.567  1.00 60.63  ?  125 LEU   B HG   1 
ATOM   1993  H  HD11 . LEU   A 1 126 ? -0.026  11.133  36.139  1.00 80.03  ?  125 LEU   B HD11 1 
ATOM   1994  H  HD12 . LEU   A 1 126 ? -1.609  11.029  36.059  1.00 80.03  ?  125 LEU   B HD12 1 
ATOM   1995  H  HD13 . LEU   A 1 126 ? -0.825  10.319  37.244  1.00 80.03  ?  125 LEU   B HD13 1 
ATOM   1996  H  HD21 . LEU   A 1 126 ? 1.330   9.486   35.067  1.00 56.06  ?  125 LEU   B HD21 1 
ATOM   1997  H  HD22 . LEU   A 1 126 ? 1.040   8.647   36.384  1.00 56.06  ?  125 LEU   B HD22 1 
ATOM   1998  H  HD23 . LEU   A 1 126 ? 0.805   7.991   34.957  1.00 56.06  ?  125 LEU   B HD23 1 
ATOM   1999  N  N    . LYS   A 1 127 ? -3.560  9.532   33.580  1.00 42.77  ?  126 LYS   B N    1 
ATOM   2000  C  CA   . LYS   A 1 127 ? -3.888  9.614   32.163  1.00 55.89  ?  126 LYS   B CA   1 
ATOM   2001  C  C    . LYS   A 1 127 ? -2.808  10.437  31.465  1.00 50.45  ?  126 LYS   B C    1 
ATOM   2002  O  O    . LYS   A 1 127 ? -2.665  11.647  31.688  1.00 47.76  ?  126 LYS   B O    1 
ATOM   2003  C  CB   . LYS   A 1 127 ? -5.279  10.206  31.927  1.00 60.80  ?  126 LYS   B CB   1 
ATOM   2004  C  CG   . LYS   A 1 127 ? -5.999  9.666   30.700  1.00 73.21  ?  126 LYS   B CG   1 
ATOM   2005  C  CD   . LYS   A 1 127 ? -5.727  10.491  29.448  1.00 76.99  ?  126 LYS   B CD   1 
ATOM   2006  C  CE   . LYS   A 1 127 ? -6.211  11.929  29.587  1.00 73.59  ?  126 LYS   B CE   1 
ATOM   2007  N  NZ   . LYS   A 1 127 ? -6.177  12.630  28.263  1.00 83.32  ?  126 LYS   B NZ   1 
ATOM   2008  H  H    . LYS   A 1 127 ? -3.482  10.298  33.963  1.00 51.32  ?  126 LYS   B H    1 
ATOM   2009  H  HA   . LYS   A 1 127 ? -3.884  8.719   31.790  1.00 67.07  ?  126 LYS   B HA   1 
ATOM   2010  H  HB2  . LYS   A 1 127 ? -5.832  10.012  32.699  1.00 72.96  ?  126 LYS   B HB2  1 
ATOM   2011  H  HB3  . LYS   A 1 127 ? -5.191  11.166  31.815  1.00 72.96  ?  126 LYS   B HB3  1 
ATOM   2012  H  HG2  . LYS   A 1 127 ? -5.701  8.758   30.531  1.00 87.85  ?  126 LYS   B HG2  1 
ATOM   2013  H  HG3  . LYS   A 1 127 ? -6.955  9.676   30.863  1.00 87.85  ?  126 LYS   B HG3  1 
ATOM   2014  H  HD2  . LYS   A 1 127 ? -4.771  10.509  29.280  1.00 92.39  ?  126 LYS   B HD2  1 
ATOM   2015  H  HD3  . LYS   A 1 127 ? -6.188  10.089  28.695  1.00 92.39  ?  126 LYS   B HD3  1 
ATOM   2016  H  HE2  . LYS   A 1 127 ? -7.124  11.933  29.914  1.00 88.30  ?  126 LYS   B HE2  1 
ATOM   2017  H  HE3  . LYS   A 1 127 ? -5.635  12.407  30.204  1.00 88.30  ?  126 LYS   B HE3  1 
ATOM   2018  H  HZ1  . LYS   A 1 127 ? -6.460  13.469  28.355  1.00 99.98  ?  126 LYS   B HZ1  1 
ATOM   2019  H  HZ2  . LYS   A 1 127 ? -5.346  12.639  27.945  1.00 99.98  ?  126 LYS   B HZ2  1 
ATOM   2020  H  HZ3  . LYS   A 1 127 ? -6.704  12.210  27.682  1.00 99.98  ?  126 LYS   B HZ3  1 
ATOM   2021  N  N    . PHE   A 1 128 ? -2.094  9.779   30.576  1.00 44.33  ?  127 PHE   B N    1 
ATOM   2022  C  CA   . PHE   A 1 128 ? -1.039  10.407  29.814  1.00 42.45  ?  127 PHE   B CA   1 
ATOM   2023  C  C    . PHE   A 1 128 ? -1.568  11.223  28.652  1.00 46.14  ?  127 PHE   B C    1 
ATOM   2024  O  O    . PHE   A 1 128 ? -2.549  10.857  28.018  1.00 40.21  ?  127 PHE   B O    1 
ATOM   2025  C  CB   . PHE   A 1 128 ? -0.132  9.313   29.274  1.00 40.67  ?  127 PHE   B CB   1 
ATOM   2026  C  CG   . PHE   A 1 128 ? 0.745   8.722   30.307  1.00 42.64  ?  127 PHE   B CG   1 
ATOM   2027  C  CD1  . PHE   A 1 128 ? 1.696   9.514   30.936  1.00 39.90  ?  127 PHE   B CD1  1 
ATOM   2028  C  CD2  . PHE   A 1 128 ? 0.620   7.396   30.663  1.00 33.81  ?  127 PHE   B CD2  1 
ATOM   2029  C  CE1  . PHE   A 1 128 ? 2.511   8.991   31.886  1.00 37.50  ?  127 PHE   B CE1  1 
ATOM   2030  C  CE2  . PHE   A 1 128 ? 1.433   6.872   31.617  1.00 39.12  ?  127 PHE   B CE2  1 
ATOM   2031  C  CZ   . PHE   A 1 128 ? 2.385   7.667   32.229  1.00 32.98  ?  127 PHE   B CZ   1 
ATOM   2032  H  H    . PHE   A 1 128 ? -2.204  8.946   30.391  1.00 53.20  ?  127 PHE   B H    1 
ATOM   2033  H  HA   . PHE   A 1 128 ? -0.549  11.018  30.385  1.00 50.94  ?  127 PHE   B HA   1 
ATOM   2034  H  HB2  . PHE   A 1 128 ? -0.681  8.603   28.906  1.00 48.81  ?  127 PHE   B HB2  1 
ATOM   2035  H  HB3  . PHE   A 1 128 ? 0.433   9.688   28.581  1.00 48.81  ?  127 PHE   B HB3  1 
ATOM   2036  H  HD1  . PHE   A 1 128 ? 1.776   10.411  30.704  1.00 47.87  ?  127 PHE   B HD1  1 
ATOM   2037  H  HD2  . PHE   A 1 128 ? -0.019  6.861   30.251  1.00 40.57  ?  127 PHE   B HD2  1 
ATOM   2038  H  HE1  . PHE   A 1 128 ? 3.150   9.524   32.301  1.00 45.00  ?  127 PHE   B HE1  1 
ATOM   2039  H  HE2  . PHE   A 1 128 ? 1.350   5.978   31.858  1.00 46.95  ?  127 PHE   B HE2  1 
ATOM   2040  H  HZ   . PHE   A 1 128 ? 2.944   7.303   32.877  1.00 39.57  ?  127 PHE   B HZ   1 
ATOM   2041  N  N    . ASN   A 1 129 ? -0.868  12.302  28.338  1.00 46.60  ?  128 ASN   B N    1 
ATOM   2042  C  CA   . ASN   A 1 129 ? -1.255  13.183  27.246  1.00 44.23  ?  128 ASN   B CA   1 
ATOM   2043  C  C    . ASN   A 1 129 ? -0.666  12.710  25.926  1.00 49.45  ?  128 ASN   B C    1 
ATOM   2044  O  O    . ASN   A 1 129 ? -1.422  12.561  24.963  1.00 49.04  ?  128 ASN   B O    1 
ATOM   2045  C  CB   . ASN   A 1 129 ? -0.864  14.618  27.588  1.00 47.18  ?  128 ASN   B CB   1 
ATOM   2046  C  CG   . ASN   A 1 129 ? -1.738  15.182  28.731  1.00 49.03  ?  128 ASN   B CG   1 
ATOM   2047  O  OD1  . ASN   A 1 129 ? -2.939  14.883  28.784  1.00 44.15  ?  128 ASN   B OD1  1 
ATOM   2048  N  ND2  . ASN   A 1 129 ? -1.142  15.961  29.650  1.00 47.59  ?  128 ASN   B ND2  1 
ATOM   2049  H  H    . ASN   A 1 129 ? -0.153  12.549  28.747  1.00 55.93  ?  128 ASN   B H    1 
ATOM   2050  H  HA   . ASN   A 1 129 ? -2.217  13.161  27.122  1.00 53.08  ?  128 ASN   B HA   1 
ATOM   2051  H  HB2  . ASN   A 1 129 ? 0.063   14.639  27.872  1.00 56.61  ?  128 ASN   B HB2  1 
ATOM   2052  H  HB3  . ASN   A 1 129 ? -0.983  15.179  26.805  1.00 56.61  ?  128 ASN   B HB3  1 
ATOM   2053  H  HD21 . ASN   A 1 129 ? -0.301  16.130  29.590  1.00 57.11  ?  128 ASN   B HD21 1 
ATOM   2054  H  HD22 . ASN   A 1 129 ? -1.601  16.290  30.298  1.00 57.11  ?  128 ASN   B HD22 1 
ATOM   2055  N  N    . PRO   A 1 130 ? 0.624   12.409  25.836  1.00 46.32  ?  129 PRO   B N    1 
ATOM   2056  C  CA   . PRO   A 1 130 ? 1.185   11.956  24.539  1.00 42.18  ?  129 PRO   B CA   1 
ATOM   2057  C  C    . PRO   A 1 130 ? 0.594   10.624  24.098  1.00 40.24  ?  129 PRO   B C    1 
ATOM   2058  O  O    . PRO   A 1 130 ? 0.682   9.616   24.811  1.00 41.10  ?  129 PRO   B O    1 
ATOM   2059  C  CB   . PRO   A 1 130 ? 2.688   11.831  24.824  1.00 43.23  ?  129 PRO   B CB   1 
ATOM   2060  C  CG   . PRO   A 1 130 ? 2.929   12.578  26.145  1.00 41.07  ?  129 PRO   B CG   1 
ATOM   2061  C  CD   . PRO   A 1 130 ? 1.647   12.509  26.906  1.00 45.48  ?  129 PRO   B CD   1 
ATOM   2062  H  HA   . PRO   A 1 130 ? 1.028   12.622  23.851  1.00 50.62  ?  129 PRO   B HA   1 
ATOM   2063  H  HB2  . PRO   A 1 130 ? 2.927   10.895  24.910  1.00 51.88  ?  129 PRO   B HB2  1 
ATOM   2064  H  HB3  . PRO   A 1 130 ? 3.192   12.238  24.102  1.00 51.88  ?  129 PRO   B HB3  1 
ATOM   2065  H  HG2  . PRO   A 1 130 ? 3.643   12.145  26.638  1.00 49.29  ?  129 PRO   B HG2  1 
ATOM   2066  H  HG3  . PRO   A 1 130 ? 3.167   13.500  25.958  1.00 49.29  ?  129 PRO   B HG3  1 
ATOM   2067  H  HD2  . PRO   A 1 130 ? 1.626   11.726  27.479  1.00 54.58  ?  129 PRO   B HD2  1 
ATOM   2068  H  HD3  . PRO   A 1 130 ? 1.515   13.311  27.436  1.00 54.58  ?  129 PRO   B HD3  1 
ATOM   2069  N  N    . PRO   A 1 131 ? -0.039  10.570  22.928  1.00 38.68  ?  130 PRO   B N    1 
ATOM   2070  C  CA   . PRO   A 1 131 ? -0.538  9.270   22.433  1.00 37.47  ?  130 PRO   B CA   1 
ATOM   2071  C  C    . PRO   A 1 131 ? 0.483   8.129   22.495  1.00 39.84  ?  130 PRO   B C    1 
ATOM   2072  O  O    . PRO   A 1 131 ? 0.108   6.969   22.754  1.00 38.37  ?  130 PRO   B O    1 
ATOM   2073  C  CB   . PRO   A 1 131 ? -0.936  9.577   20.990  1.00 37.07  ?  130 PRO   B CB   1 
ATOM   2074  C  CG   . PRO   A 1 131 ? -1.223  11.006  20.984  1.00 42.16  ?  130 PRO   B CG   1 
ATOM   2075  C  CD   . PRO   A 1 131 ? -0.512  11.693  22.114  1.00 34.02  ?  130 PRO   B CD   1 
ATOM   2076  H  HA   . PRO   A 1 131 ? -1.322  9.018   22.946  1.00 44.97  ?  130 PRO   B HA   1 
ATOM   2077  H  HB2  . PRO   A 1 131 ? -0.203  9.367   20.391  1.00 44.48  ?  130 PRO   B HB2  1 
ATOM   2078  H  HB3  . PRO   A 1 131 ? -1.722  9.063   20.746  1.00 44.48  ?  130 PRO   B HB3  1 
ATOM   2079  H  HG2  . PRO   A 1 131 ? -0.925  11.376  20.138  1.00 50.59  ?  130 PRO   B HG2  1 
ATOM   2080  H  HG3  . PRO   A 1 131 ? -2.181  11.128  21.079  1.00 50.59  ?  130 PRO   B HG3  1 
ATOM   2081  H  HD2  . PRO   A 1 131 ? 0.232   12.222  21.785  1.00 40.82  ?  130 PRO   B HD2  1 
ATOM   2082  H  HD3  . PRO   A 1 131 ? -1.121  12.255  22.617  1.00 40.82  ?  130 PRO   B HD3  1 
ATOM   2083  N  N    . ALA   A 1 132 ? 1.764   8.424   22.274  1.00 33.52  ?  131 ALA   B N    1 
ATOM   2084  C  CA   . ALA   A 1 132 ? 2.797   7.397   22.400  1.00 36.88  ?  131 ALA   B CA   1 
ATOM   2085  C  C    . ALA   A 1 132 ? 2.749   6.733   23.770  1.00 33.73  ?  131 ALA   B C    1 
ATOM   2086  O  O    . ALA   A 1 132 ? 2.800   5.500   23.881  1.00 35.45  ?  131 ALA   B O    1 
ATOM   2087  C  CB   . ALA   A 1 132 ? 4.161   8.024   22.156  1.00 33.84  ?  131 ALA   B CB   1 
ATOM   2088  H  H    . ALA   A 1 132 ? 2.059   9.201   22.053  1.00 40.22  ?  131 ALA   B H    1 
ATOM   2089  H  HA   . ALA   A 1 132 ? 2.648   6.710   21.732  1.00 44.26  ?  131 ALA   B HA   1 
ATOM   2090  H  HB1  . ALA   A 1 132 ? 4.834   7.326   22.155  1.00 40.61  ?  131 ALA   B HB1  1 
ATOM   2091  H  HB2  . ALA   A 1 132 ? 4.152   8.476   21.298  1.00 40.61  ?  131 ALA   B HB2  1 
ATOM   2092  H  HB3  . ALA   A 1 132 ? 4.347   8.661   22.864  1.00 40.61  ?  131 ALA   B HB3  1 
ATOM   2093  N  N    . LEU   A 1 133 ? 2.625   7.542   24.833  1.00 34.43  ?  132 LEU   B N    1 
ATOM   2094  C  CA   . LEU   A 1 133 ? 2.593   6.982   26.189  1.00 40.57  ?  132 LEU   B CA   1 
ATOM   2095  C  C    . LEU   A 1 133 ? 1.275   6.297   26.466  1.00 40.67  ?  132 LEU   B C    1 
ATOM   2096  O  O    . LEU   A 1 133 ? 1.247   5.310   27.213  1.00 41.31  ?  132 LEU   B O    1 
ATOM   2097  C  CB   . LEU   A 1 133 ? 2.806   8.038   27.274  1.00 35.65  ?  132 LEU   B CB   1 
ATOM   2098  C  CG   . LEU   A 1 133 ? 4.216   8.632   27.252  1.00 41.52  ?  132 LEU   B CG   1 
ATOM   2099  C  CD1  . LEU   A 1 133 ? 4.471   9.754   28.282  1.00 40.58  ?  132 LEU   B CD1  1 
ATOM   2100  C  CD2  . LEU   A 1 133 ? 5.243   7.502   27.484  1.00 42.04  ?  132 LEU   B CD2  1 
ATOM   2101  H  H    . LEU   A 1 133 ? 2.559   8.399   24.796  1.00 41.31  ?  132 LEU   B H    1 
ATOM   2102  H  HA   . LEU   A 1 133 ? 3.330   6.354   26.241  1.00 48.68  ?  132 LEU   B HA   1 
ATOM   2103  H  HB2  . LEU   A 1 133 ? 2.173   8.760   27.140  1.00 42.78  ?  132 LEU   B HB2  1 
ATOM   2104  H  HB3  . LEU   A 1 133 ? 2.664   7.631   28.143  1.00 42.78  ?  132 LEU   B HB3  1 
ATOM   2105  H  HG   . LEU   A 1 133 ? 4.321   9.048   26.382  1.00 49.83  ?  132 LEU   B HG   1 
ATOM   2106  H  HD11 . LEU   A 1 133 ? 5.324   10.173  28.087  1.00 48.69  ?  132 LEU   B HD11 1 
ATOM   2107  H  HD12 . LEU   A 1 133 ? 3.758   10.408  28.219  1.00 48.69  ?  132 LEU   B HD12 1 
ATOM   2108  H  HD13 . LEU   A 1 133 ? 4.488   9.367   29.171  1.00 48.69  ?  132 LEU   B HD13 1 
ATOM   2109  H  HD21 . LEU   A 1 133 ? 6.076   7.891   27.794  1.00 50.45  ?  132 LEU   B HD21 1 
ATOM   2110  H  HD22 . LEU   A 1 133 ? 4.895   6.891   28.152  1.00 50.45  ?  132 LEU   B HD22 1 
ATOM   2111  H  HD23 . LEU   A 1 133 ? 5.389   7.032   26.648  1.00 50.45  ?  132 LEU   B HD23 1 
ATOM   2112  N  N    . GLN   A 1 134 ? 0.168   6.806   25.892  1.00 38.47  ?  133 GLN   B N    1 
ATOM   2113  C  CA   . GLN   A 1 134 ? -1.112  6.147   26.140  1.00 34.88  ?  133 GLN   B CA   1 
ATOM   2114  C  C    . GLN   A 1 134 ? -1.126  4.755   25.514  1.00 41.19  ?  133 GLN   B C    1 
ATOM   2115  O  O    . GLN   A 1 134 ? -1.581  3.782   26.132  1.00 35.79  ?  133 GLN   B O    1 
ATOM   2116  C  CB   . GLN   A 1 134 ? -2.263  6.966   25.584  1.00 34.32  ?  133 GLN   B CB   1 
ATOM   2117  C  CG   . GLN   A 1 134 ? -2.240  8.493   25.729  1.00 44.97  ?  133 GLN   B CG   1 
ATOM   2118  C  CD   . GLN   A 1 134 ? -3.492  9.143   25.022  1.00 52.95  ?  133 GLN   B CD   1 
ATOM   2119  O  OE1  . GLN   A 1 134 ? -4.010  8.623   24.009  1.00 48.47  ?  133 GLN   B OE1  1 
ATOM   2120  N  NE2  . GLN   A 1 134 ? -3.954  10.270  25.558  1.00 53.84  ?  133 GLN   B NE2  1 
ATOM   2121  H  H    . GLN   A 1 134 ? 0.140   7.497   25.381  1.00 46.17  ?  133 GLN   B H    1 
ATOM   2122  H  HA   . GLN   A 1 134 ? -1.237  6.074   27.099  1.00 41.86  ?  133 GLN   B HA   1 
ATOM   2123  H  HB2  . GLN   A 1 134 ? -2.316  6.784   24.633  1.00 41.18  ?  133 GLN   B HB2  1 
ATOM   2124  H  HB3  . GLN   A 1 134 ? -3.073  6.663   26.024  1.00 41.18  ?  133 GLN   B HB3  1 
ATOM   2125  H  HG2  . GLN   A 1 134 ? -2.260  8.729   26.669  1.00 53.96  ?  133 GLN   B HG2  1 
ATOM   2126  H  HG3  . GLN   A 1 134 ? -1.435  8.844   25.316  1.00 53.96  ?  133 GLN   B HG3  1 
ATOM   2127  H  HE21 . GLN   A 1 134 ? -3.572  10.604  26.253  1.00 64.60  ?  133 GLN   B HE21 1 
ATOM   2128  H  HE22 . GLN   A 1 134 ? -4.634  10.664  25.211  1.00 64.60  ?  133 GLN   B HE22 1 
ATOM   2129  N  N    . ASP   A 1 135 ? -0.614  4.636   24.280  1.00 38.20  ?  134 ASP   B N    1 
ATOM   2130  C  CA   . ASP   A 1 135 ? -0.714  3.364   23.573  1.00 42.73  ?  134 ASP   B CA   1 
ATOM   2131  C  C    . ASP   A 1 135 ? 0.226   2.352   24.187  1.00 42.19  ?  134 ASP   B C    1 
ATOM   2132  O  O    . ASP   A 1 135 ? -0.175  1.224   24.482  1.00 36.33  ?  134 ASP   B O    1 
ATOM   2133  C  CB   . ASP   A 1 135 ? -0.434  3.552   22.078  1.00 62.92  ?  134 ASP   B CB   1 
ATOM   2134  C  CG   . ASP   A 1 135 ? -1.547  4.361   21.360  1.00 53.26  ?  134 ASP   B CG   1 
ATOM   2135  O  OD1  . ASP   A 1 135 ? -2.700  4.432   21.878  1.00 55.85  ?  134 ASP   B OD1  1 
ATOM   2136  O  OD2  . ASP   A 1 135 ? -1.246  4.936   20.287  1.00 48.41  -1 134 ASP   B OD2  1 
ATOM   2137  H  H    . ASP   A 1 135 ? -0.216  5.262   23.847  1.00 45.84  ?  134 ASP   B H    1 
ATOM   2138  H  HA   . ASP   A 1 135 ? -1.621  3.027   23.648  1.00 51.27  ?  134 ASP   B HA   1 
ATOM   2139  H  HB2  . ASP   A 1 135 ? 0.402   4.030   21.970  1.00 75.50  ?  134 ASP   B HB2  1 
ATOM   2140  H  HB3  . ASP   A 1 135 ? -0.376  2.681   21.655  1.00 75.50  ?  134 ASP   B HB3  1 
ATOM   2141  N  N    . ALA   A 1 136 ? 1.476   2.764   24.429  1.00 43.15  ?  135 ALA   B N    1 
ATOM   2142  C  CA   . ALA   A 1 136 ? 2.447   1.887   25.064  1.00 37.44  ?  135 ALA   B CA   1 
ATOM   2143  C  C    . ALA   A 1 136 ? 2.002   1.484   26.454  1.00 35.58  ?  135 ALA   B C    1 
ATOM   2144  O  O    . ALA   A 1 136 ? 2.172   0.326   26.857  1.00 31.55  ?  135 ALA   B O    1 
ATOM   2145  C  CB   . ALA   A 1 136 ? 3.805   2.579   25.129  1.00 40.80  ?  135 ALA   B CB   1 
ATOM   2146  H  H    . ALA   A 1 136 ? 1.780   3.545   24.235  1.00 51.78  ?  135 ALA   B H    1 
ATOM   2147  H  HA   . ALA   A 1 136 ? 2.536   1.083   24.529  1.00 44.93  ?  135 ALA   B HA   1 
ATOM   2148  H  HB1  . ALA   A 1 136 ? 4.441   1.987   25.561  1.00 48.96  ?  135 ALA   B HB1  1 
ATOM   2149  H  HB2  . ALA   A 1 136 ? 4.101   2.780   24.227  1.00 48.96  ?  135 ALA   B HB2  1 
ATOM   2150  H  HB3  . ALA   A 1 136 ? 3.718   3.400   25.638  1.00 48.96  ?  135 ALA   B HB3  1 
ATOM   2151  N  N    . TYR   A 1 137 ? 1.414   2.414   27.205  1.00 35.00  ?  136 TYR   B N    1 
ATOM   2152  C  CA   . TYR   A 1 137 ? 0.946   2.019   28.529  1.00 43.02  ?  136 TYR   B CA   1 
ATOM   2153  C  C    . TYR   A 1 137 ? -0.124  0.940   28.433  1.00 42.06  ?  136 TYR   B C    1 
ATOM   2154  O  O    . TYR   A 1 137 ? -0.175  0.025   29.272  1.00 36.25  ?  136 TYR   B O    1 
ATOM   2155  C  CB   . TYR   A 1 137 ? 0.373   3.185   29.321  1.00 38.53  ?  136 TYR   B CB   1 
ATOM   2156  C  CG   . TYR   A 1 137 ? -0.058  2.749   30.709  1.00 42.58  ?  136 TYR   B CG   1 
ATOM   2157  C  CD1  . TYR   A 1 137 ? -1.397  2.567   31.037  1.00 57.47  ?  136 TYR   B CD1  1 
ATOM   2158  C  CD2  . TYR   A 1 137 ? 0.875   2.502   31.675  1.00 40.89  ?  136 TYR   B CD2  1 
ATOM   2159  C  CE1  . TYR   A 1 137 ? -1.768  2.178   32.312  1.00 59.43  ?  136 TYR   B CE1  1 
ATOM   2160  C  CE2  . TYR   A 1 137 ? 0.530   2.116   32.934  1.00 41.68  ?  136 TYR   B CE2  1 
ATOM   2161  C  CZ   . TYR   A 1 137 ? -0.780  1.965   33.271  1.00 52.50  ?  136 TYR   B CZ   1 
ATOM   2162  O  OH   . TYR   A 1 137 ? -1.106  1.579   34.558  1.00 52.52  ?  136 TYR   B OH   1 
ATOM   2163  H  H    . TYR   A 1 137 ? 1.281   3.234   26.984  1.00 42.00  ?  136 TYR   B H    1 
ATOM   2164  H  HA   . TYR   A 1 137 ? 1.724   1.689   29.005  1.00 51.62  ?  136 TYR   B HA   1 
ATOM   2165  H  HB2  . TYR   A 1 137 ? 1.050   3.874   29.413  1.00 46.23  ?  136 TYR   B HB2  1 
ATOM   2166  H  HB3  . TYR   A 1 137 ? -0.401  3.540   28.857  1.00 46.23  ?  136 TYR   B HB3  1 
ATOM   2167  H  HD1  . TYR   A 1 137 ? -2.051  2.709   30.392  1.00 68.97  ?  136 TYR   B HD1  1 
ATOM   2168  H  HD2  . TYR   A 1 137 ? 1.776   2.602   31.467  1.00 49.07  ?  136 TYR   B HD2  1 
ATOM   2169  H  HE1  . TYR   A 1 137 ? -2.665  2.059   32.525  1.00 71.32  ?  136 TYR   B HE1  1 
ATOM   2170  H  HE2  . TYR   A 1 137 ? 1.192   1.954   33.566  1.00 50.01  ?  136 TYR   B HE2  1 
ATOM   2171  H  HH   . TYR   A 1 137 ? -0.419  1.585   35.042  1.00 63.03  ?  136 TYR   B HH   1 
ATOM   2172  N  N    . TYR   A 1 138 ? -1.053  1.092   27.474  1.00 49.97  ?  137 TYR   B N    1 
ATOM   2173  C  CA   . TYR   A 1 138 ? -2.091  0.082   27.263  1.00 49.46  ?  137 TYR   B CA   1 
ATOM   2174  C  C    . TYR   A 1 138 ? -1.445  -1.272  27.009  1.00 45.81  ?  137 TYR   B C    1 
ATOM   2175  O  O    . TYR   A 1 138 ? -1.818  -2.281  27.620  1.00 41.53  ?  137 TYR   B O    1 
ATOM   2176  C  CB   . TYR   A 1 138 ? -2.993  0.490   26.080  1.00 52.16  ?  137 TYR   B CB   1 
ATOM   2177  C  CG   . TYR   A 1 138 ? -4.031  -0.548  25.697  1.00 60.12  ?  137 TYR   B CG   1 
ATOM   2178  C  CD1  . TYR   A 1 138 ? -5.318  -0.512  26.257  1.00 71.56  ?  137 TYR   B CD1  1 
ATOM   2179  C  CD2  . TYR   A 1 138 ? -3.740  -1.564  24.791  1.00 56.43  ?  137 TYR   B CD2  1 
ATOM   2180  C  CE1  . TYR   A 1 138 ? -6.289  -1.457  25.927  1.00 69.77  ?  137 TYR   B CE1  1 
ATOM   2181  C  CE2  . TYR   A 1 138 ? -4.705  -2.520  24.463  1.00 64.02  ?  137 TYR   B CE2  1 
ATOM   2182  C  CZ   . TYR   A 1 138 ? -5.978  -2.457  25.041  1.00 69.77  ?  137 TYR   B CZ   1 
ATOM   2183  O  OH   . TYR   A 1 138 ? -6.961  -3.382  24.731  1.00 85.31  ?  137 TYR   B OH   1 
ATOM   2184  H  H    . TYR   A 1 138 ? -1.100  1.764   26.939  1.00 59.97  ?  137 TYR   B H    1 
ATOM   2185  H  HA   . TYR   A 1 138 ? -2.653  0.021   28.051  1.00 59.35  ?  137 TYR   B HA   1 
ATOM   2186  H  HB2  . TYR   A 1 138 ? -3.465  1.304   26.316  1.00 62.60  ?  137 TYR   B HB2  1 
ATOM   2187  H  HB3  . TYR   A 1 138 ? -2.432  0.646   25.303  1.00 62.60  ?  137 TYR   B HB3  1 
ATOM   2188  H  HD1  . TYR   A 1 138 ? -5.528  0.161   26.864  1.00 85.87  ?  137 TYR   B HD1  1 
ATOM   2189  H  HD2  . TYR   A 1 138 ? -2.897  -1.607  24.400  1.00 67.71  ?  137 TYR   B HD2  1 
ATOM   2190  H  HE1  . TYR   A 1 138 ? -7.138  -1.410  26.304  1.00 83.72  ?  137 TYR   B HE1  1 
ATOM   2191  H  HE2  . TYR   A 1 138 ? -4.501  -3.199  23.861  1.00 76.82  ?  137 TYR   B HE2  1 
ATOM   2192  H  HH   . TYR   A 1 138 ? -6.657  -3.956  24.198  1.00 102.37 ?  137 TYR   B HH   1 
ATOM   2193  N  N    . ARG   A 1 139 ? -0.434  -1.295  26.128  1.00 39.19  ?  138 ARG   B N    1 
ATOM   2194  C  CA   . ARG   A 1 139 ? 0.301   -2.525  25.848  1.00 45.65  ?  138 ARG   B CA   1 
ATOM   2195  C  C    . ARG   A 1 139 ? 0.957   -3.075  27.100  1.00 41.26  ?  138 ARG   B C    1 
ATOM   2196  O  O    . ARG   A 1 139 ? 1.015   -4.299  27.295  1.00 33.81  ?  138 ARG   B O    1 
ATOM   2197  C  CB   . ARG   A 1 139 ? 1.396   -2.272  24.807  1.00 50.20  ?  138 ARG   B CB   1 
ATOM   2198  C  CG   . ARG   A 1 139 ? 0.895   -1.836  23.469  1.00 53.13  ?  138 ARG   B CG   1 
ATOM   2199  C  CD   . ARG   A 1 139 ? 0.586   -3.068  22.641  1.00 55.30  ?  138 ARG   B CD   1 
ATOM   2200  N  NE   . ARG   A 1 139 ? 1.607   -3.229  21.614  1.00 58.24  ?  138 ARG   B NE   1 
ATOM   2201  C  CZ   . ARG   A 1 139 ? 2.383   -4.295  21.507  1.00 64.35  ?  138 ARG   B CZ   1 
ATOM   2202  N  NH1  . ARG   A 1 139 ? 2.259   -5.324  22.330  1.00 63.83  ?  138 ARG   B NH1  1 
ATOM   2203  N  NH2  . ARG   A 1 139 ? 3.290   -4.343  20.532  1.00 74.99  ?  138 ARG   B NH2  1 
ATOM   2204  H  H    . ARG   A 1 139 ? -0.159  -0.612  25.683  1.00 47.02  ?  138 ARG   B H    1 
ATOM   2205  H  HA   . ARG   A 1 139 ? -0.333  -3.171  25.500  1.00 54.78  ?  138 ARG   B HA   1 
ATOM   2206  H  HB2  . ARG   A 1 139 ? 1.984   -1.576  25.141  1.00 60.24  ?  138 ARG   B HB2  1 
ATOM   2207  H  HB3  . ARG   A 1 139 ? 1.895   -3.094  24.679  1.00 60.24  ?  138 ARG   B HB3  1 
ATOM   2208  H  HG2  . ARG   A 1 139 ? 0.086   -1.312  23.572  1.00 63.75  ?  138 ARG   B HG2  1 
ATOM   2209  H  HG3  . ARG   A 1 139 ? 1.574   -1.311  23.015  1.00 63.75  ?  138 ARG   B HG3  1 
ATOM   2210  H  HD2  . ARG   A 1 139 ? 0.585   -3.854  23.209  1.00 66.36  ?  138 ARG   B HD2  1 
ATOM   2211  H  HD3  . ARG   A 1 139 ? -0.278  -2.968  22.212  1.00 66.36  ?  138 ARG   B HD3  1 
ATOM   2212  H  HE   . ARG   A 1 139 ? 1.711   -2.593  21.044  1.00 69.88  ?  138 ARG   B HE   1 
ATOM   2213  H  HH11 . ARG   A 1 139 ? 1.665   -5.309  22.951  1.00 76.60  ?  138 ARG   B HH11 1 
ATOM   2214  H  HH12 . ARG   A 1 139 ? 2.774   -6.008  22.244  1.00 76.60  ?  138 ARG   B HH12 1 
ATOM   2215  H  HH21 . ARG   A 1 139 ? 3.365   -3.686  19.982  1.00 89.99  ?  138 ARG   B HH21 1 
ATOM   2216  H  HH22 . ARG   A 1 139 ? 3.800   -5.031  20.452  1.00 89.99  ?  138 ARG   B HH22 1 
ATOM   2217  N  N    . ALA   A 1 140 ? 1.533   -2.175  27.916  1.00 38.92  ?  139 ALA   B N    1 
ATOM   2218  C  CA   . ALA   A 1 140 ? 2.250   -2.581  29.124  1.00 36.83  ?  139 ALA   B CA   1 
ATOM   2219  C  C    . ALA   A 1 140 ? 1.323   -3.311  30.080  1.00 34.33  ?  139 ALA   B C    1 
ATOM   2220  O  O    . ALA   A 1 140 ? 1.633   -4.415  30.550  1.00 34.72  ?  139 ALA   B O    1 
ATOM   2221  C  CB   . ALA   A 1 140 ? 2.849   -1.353  29.821  1.00 26.75  ?  139 ALA   B CB   1 
ATOM   2222  H  H    . ALA   A 1 140 ? 1.521   -1.325  27.787  1.00 46.71  ?  139 ALA   B H    1 
ATOM   2223  H  HA   . ALA   A 1 140 ? 2.973   -3.175  28.869  1.00 44.19  ?  139 ALA   B HA   1 
ATOM   2224  H  HB1  . ALA   A 1 140 ? 3.301   -1.639  30.630  1.00 32.10  ?  139 ALA   B HB1  1 
ATOM   2225  H  HB2  . ALA   A 1 140 ? 3.482   -0.927  29.221  1.00 32.10  ?  139 ALA   B HB2  1 
ATOM   2226  H  HB3  . ALA   A 1 140 ? 2.135   -0.735  30.041  1.00 32.10  ?  139 ALA   B HB3  1 
ATOM   2227  N  N    . ARG   A 1 141 ? 0.184   -2.711  30.330  1.00 39.26  ?  140 ARG   B N    1 
ATOM   2228  C  CA   . ARG   A 1 141 ? -0.826  -3.255  31.196  1.00 44.12  ?  140 ARG   B CA   1 
ATOM   2229  C  C    . ARG   A 1 141 ? -1.188  -4.655  30.761  1.00 40.69  ?  140 ARG   B C    1 
ATOM   2230  O  O    . ARG   A 1 141 ? -1.396  -5.519  31.561  1.00 36.44  ?  140 ARG   B O    1 
ATOM   2231  C  CB   . ARG   A 1 141 ? -2.034  -2.370  31.096  1.00 41.14  ?  140 ARG   B CB   1 
ATOM   2232  C  CG   . ARG   A 1 141 ? -2.928  -2.340  32.297  1.00 72.14  ?  140 ARG   B CG   1 
ATOM   2233  C  CD   . ARG   A 1 141 ? -3.568  -0.973  32.420  1.00 63.94  ?  140 ARG   B CD   1 
ATOM   2234  N  NE   . ARG   A 1 141 ? -3.298  -0.333  33.692  1.00 70.44  ?  140 ARG   B NE   1 
ATOM   2235  C  CZ   . ARG   A 1 141 ? -4.159  0.413   34.370  1.00 70.32  ?  140 ARG   B CZ   1 
ATOM   2236  N  NH1  . ARG   A 1 141 ? -3.799  0.958   35.507  1.00 46.15  ?  140 ARG   B NH1  1 
ATOM   2237  N  NH2  . ARG   A 1 141 ? -5.380  0.624   33.898  1.00 75.21  ?  140 ARG   B NH2  1 
ATOM   2238  H  H    . ARG   A 1 141 ? -0.034  -1.951  29.992  1.00 47.12  ?  140 ARG   B H    1 
ATOM   2239  H  HA   . ARG   A 1 141 ? -0.509  -3.272  32.123  1.00 52.94  ?  140 ARG   B HA   1 
ATOM   2240  H  HB2  . ARG   A 1 141 ? -1.727  -1.461  30.950  1.00 49.36  ?  140 ARG   B HB2  1 
ATOM   2241  H  HB3  . ARG   A 1 141 ? -2.579  -2.645  30.343  1.00 49.36  ?  140 ARG   B HB3  1 
ATOM   2242  H  HG2  . ARG   A 1 141 ? -3.629  -3.003  32.198  1.00 86.57  ?  140 ARG   B HG2  1 
ATOM   2243  H  HG3  . ARG   A 1 141 ? -2.406  -2.512  33.096  1.00 86.57  ?  140 ARG   B HG3  1 
ATOM   2244  H  HD2  . ARG   A 1 141 ? -3.224  -0.399  31.718  1.00 76.73  ?  140 ARG   B HD2  1 
ATOM   2245  H  HD3  . ARG   A 1 141 ? -4.530  -1.066  32.330  1.00 76.73  ?  140 ARG   B HD3  1 
ATOM   2246  H  HE   . ARG   A 1 141 ? -2.400  -0.413  34.050  1.00 84.53  ?  140 ARG   B HE   1 
ATOM   2247  H  HH11 . ARG   A 1 141 ? -3.008  0.823   35.817  1.00 55.38  ?  140 ARG   B HH11 1 
ATOM   2248  H  HH12 . ARG   A 1 141 ? -4.358  1.439   35.950  1.00 55.38  ?  140 ARG   B HH12 1 
ATOM   2249  H  HH21 . ARG   A 1 141 ? -5.619  0.272   33.150  1.00 90.26  ?  140 ARG   B HH21 1 
ATOM   2250  H  HH22 . ARG   A 1 141 ? -5.935  1.108   34.342  1.00 90.26  ?  140 ARG   B HH22 1 
ATOM   2251  N  N    . ALA   A 1 142 ? -1.195  -4.845  29.458  1.00 38.78  ?  141 ALA   B N    1 
ATOM   2252  C  CA   . ALA   A 1 142 ? -1.564  -6.123  28.854  1.00 42.89  ?  141 ALA   B CA   1 
ATOM   2253  C  C    . ALA   A 1 142 ? -0.488  -7.198  29.033  1.00 44.54  ?  141 ALA   B C    1 
ATOM   2254  O  O    . ALA   A 1 142 ? -0.801  -8.395  29.008  1.00 43.85  ?  141 ALA   B O    1 
ATOM   2255  C  CB   . ALA   A 1 142 ? -1.857  -5.917  27.357  1.00 37.40  ?  141 ALA   B CB   1 
ATOM   2256  H  H    . ALA   A 1 142 ? -0.984  -4.238  28.887  1.00 46.53  ?  141 ALA   B H    1 
ATOM   2257  H  HA   . ALA   A 1 142 ? -2.366  -6.446  29.293  1.00 51.46  ?  141 ALA   B HA   1 
ATOM   2258  H  HB1  . ALA   A 1 142 ? -2.102  -6.769  26.963  1.00 44.88  ?  141 ALA   B HB1  1 
ATOM   2259  H  HB2  . ALA   A 1 142 ? -2.589  -5.287  27.262  1.00 44.88  ?  141 ALA   B HB2  1 
ATOM   2260  H  HB3  . ALA   A 1 142 ? -1.062  -5.569  26.924  1.00 44.88  ?  141 ALA   B HB3  1 
ATOM   2261  N  N    . GLY   A 1 143 ? 0.777   -6.805  29.196  1.00 45.36  ?  142 GLY   B N    1 
ATOM   2262  C  CA   . GLY   A 1 143 ? 1.837   -7.775  29.425  1.00 38.90  ?  142 GLY   B CA   1 
ATOM   2263  C  C    . GLY   A 1 143 ? 3.115   -7.539  28.642  1.00 44.33  ?  142 GLY   B C    1 
ATOM   2264  O  O    . GLY   A 1 143 ? 4.163   -8.121  28.960  1.00 47.00  ?  142 GLY   B O    1 
ATOM   2265  H  H    . GLY   A 1 143 ? 1.041   -5.987  29.177  1.00 54.43  ?  142 GLY   B H    1 
ATOM   2266  H  HA2  . GLY   A 1 143 ? 2.065   -7.767  30.368  1.00 46.67  ?  142 GLY   B HA2  1 
ATOM   2267  H  HA3  . GLY   A 1 143 ? 1.506   -8.656  29.188  1.00 46.67  ?  142 GLY   B HA3  1 
ATOM   2268  N  N    . GLU   A 1 144 ? 3.046   -6.686  27.628  1.00 39.19  ?  143 GLU   B N    1 
ATOM   2269  C  CA   . GLU   A 1 144 ? 4.180   -6.401  26.756  1.00 41.81  ?  143 GLU   B CA   1 
ATOM   2270  C  C    . GLU   A 1 144 ? 4.611   -4.950  26.945  1.00 38.75  ?  143 GLU   B C    1 
ATOM   2271  O  O    . GLU   A 1 144 ? 4.116   -4.023  26.291  1.00 35.54  ?  143 GLU   B O    1 
ATOM   2272  C  CB   . GLU   A 1 144 ? 3.843   -6.658  25.267  1.00 49.80  ?  143 GLU   B CB   1 
ATOM   2273  C  CG   . GLU   A 1 144 ? 5.084   -7.043  24.410  1.00 67.22  ?  143 GLU   B CG   1 
ATOM   2274  C  CD   . GLU   A 1 144 ? 6.054   -5.875  24.094  1.00 64.17  ?  143 GLU   B CD   1 
ATOM   2275  O  OE1  . GLU   A 1 144 ? 7.204   -5.914  24.583  1.00 54.01  ?  143 GLU   B OE1  1 
ATOM   2276  O  OE2  . GLU   A 1 144 ? 5.659   -4.920  23.380  1.00 63.09  -1 143 GLU   B OE2  1 
ATOM   2277  H  H    . GLU   A 1 144 ? 2.335   -6.250  27.419  1.00 47.03  ?  143 GLU   B H    1 
ATOM   2278  H  HA   . GLU   A 1 144 ? 4.903   -6.986  27.033  1.00 50.17  ?  143 GLU   B HA   1 
ATOM   2279  H  HB2  . GLU   A 1 144 ? 3.205   -7.387  25.211  1.00 59.77  ?  143 GLU   B HB2  1 
ATOM   2280  H  HB3  . GLU   A 1 144 ? 3.459   -5.851  24.889  1.00 59.77  ?  143 GLU   B HB3  1 
ATOM   2281  H  HG2  . GLU   A 1 144 ? 5.590   -7.718  24.889  1.00 80.67  ?  143 GLU   B HG2  1 
ATOM   2282  H  HG3  . GLU   A 1 144 ? 4.774   -7.399  23.563  1.00 80.67  ?  143 GLU   B HG3  1 
ATOM   2283  N  N    . ALA   A 1 145 ? 5.591   -4.758  27.802  1.00 45.97  ?  144 ALA   B N    1 
ATOM   2284  C  CA   . ALA   A 1 145 ? 5.962   -3.415  28.211  1.00 39.12  ?  144 ALA   B CA   1 
ATOM   2285  C  C    . ALA   A 1 145 ? 7.120   -2.828  27.440  1.00 38.28  ?  144 ALA   B C    1 
ATOM   2286  O  O    . ALA   A 1 145 ? 7.514   -1.698  27.740  1.00 42.73  ?  144 ALA   B O    1 
ATOM   2287  C  CB   . ALA   A 1 145 ? 6.306   -3.395  29.707  1.00 42.76  ?  144 ALA   B CB   1 
ATOM   2288  H  H    . ALA   A 1 145 ? 6.056   -5.385  28.161  1.00 55.17  ?  144 ALA   B H    1 
ATOM   2289  H  HA   . ALA   A 1 145 ? 5.192   -2.845  28.056  1.00 46.95  ?  144 ALA   B HA   1 
ATOM   2290  H  HB1  . ALA   A 1 145 ? 6.473   -2.480  29.981  1.00 51.32  ?  144 ALA   B HB1  1 
ATOM   2291  H  HB2  . ALA   A 1 145 ? 5.560   -3.760  30.208  1.00 51.32  ?  144 ALA   B HB2  1 
ATOM   2292  H  HB3  . ALA   A 1 145 ? 7.099   -3.934  29.856  1.00 51.32  ?  144 ALA   B HB3  1 
ATOM   2293  N  N    . ALA   A 1 146 ? 7.645   -3.523  26.432  1.00 39.82  ?  145 ALA   B N    1 
ATOM   2294  C  CA   . ALA   A 1 146 ? 8.921   -3.102  25.867  1.00 34.13  ?  145 ALA   B CA   1 
ATOM   2295  C  C    . ALA   A 1 146 ? 8.858   -1.697  25.266  1.00 39.18  ?  145 ALA   B C    1 
ATOM   2296  O  O    . ALA   A 1 146 ? 9.825   -0.923  25.364  1.00 36.17  ?  145 ALA   B O    1 
ATOM   2297  C  CB   . ALA   A 1 146 ? 9.388   -4.104  24.811  1.00 41.41  ?  145 ALA   B CB   1 
ATOM   2298  H  H    . ALA   A 1 146 ? 7.294   -4.219  26.069  1.00 47.79  ?  145 ALA   B H    1 
ATOM   2299  H  HA   . ALA   A 1 146 ? 9.570   -3.083  26.587  1.00 40.96  ?  145 ALA   B HA   1 
ATOM   2300  H  HB1  . ALA   A 1 146 ? 10.232  -3.803  24.440  1.00 49.69  ?  145 ALA   B HB1  1 
ATOM   2301  H  HB2  . ALA   A 1 146 ? 9.501   -4.973  25.228  1.00 49.69  ?  145 ALA   B HB2  1 
ATOM   2302  H  HB3  . ALA   A 1 146 ? 8.719   -4.159  24.110  1.00 49.69  ?  145 ALA   B HB3  1 
ATOM   2303  N  N    . ASN   A 1 147 ? 7.779   -1.359  24.566  1.00 38.52  ?  146 ASN   B N    1 
ATOM   2304  C  CA   . ASN   A 1 147 ? 7.728   -0.000  24.015  1.00 42.49  ?  146 ASN   B CA   1 
ATOM   2305  C  C    . ASN   A 1 147 ? 7.625   1.040   25.130  1.00 37.46  ?  146 ASN   B C    1 
ATOM   2306  O  O    . ASN   A 1 147 ? 8.206   2.135   25.030  1.00 31.82  ?  146 ASN   B O    1 
ATOM   2307  C  CB   . ASN   A 1 147 ? 6.554   0.168   23.035  1.00 36.58  ?  146 ASN   B CB   1 
ATOM   2308  C  CG   . ASN   A 1 147 ? 6.758   -0.625  21.777  1.00 44.97  ?  146 ASN   B CG   1 
ATOM   2309  O  OD1  . ASN   A 1 147 ? 6.296   -1.751  21.655  1.00 52.88  ?  146 ASN   B OD1  1 
ATOM   2310  N  ND2  . ASN   A 1 147 ? 7.517   -0.066  20.855  1.00 38.44  ?  146 ASN   B ND2  1 
ATOM   2311  H  H    . ASN   A 1 147 ? 7.101   -1.864  24.403  1.00 46.22  ?  146 ASN   B H    1 
ATOM   2312  H  HA   . ASN   A 1 147 ? 8.547   0.146   23.516  1.00 50.98  ?  146 ASN   B HA   1 
ATOM   2313  H  HB2  . ASN   A 1 147 ? 5.738   -0.139  23.459  1.00 43.89  ?  146 ASN   B HB2  1 
ATOM   2314  H  HB3  . ASN   A 1 147 ? 6.471   1.104   22.794  1.00 43.89  ?  146 ASN   B HB3  1 
ATOM   2315  H  HD21 . ASN   A 1 147 ? 7.863   0.709   20.995  1.00 46.13  ?  146 ASN   B HD21 1 
ATOM   2316  H  HD22 . ASN   A 1 147 ? 7.667   -0.476  20.114  1.00 46.13  ?  146 ASN   B HD22 1 
ATOM   2317  N  N    . PHE   A 1 148 ? 6.856   0.725   26.182  1.00 31.90  ?  147 PHE   B N    1 
ATOM   2318  C  CA   . PHE   A 1 148 ? 6.673   1.669   27.279  1.00 35.43  ?  147 PHE   B CA   1 
ATOM   2319  C  C    . PHE   A 1 148 ? 7.991   1.946   27.995  1.00 34.57  ?  147 PHE   B C    1 
ATOM   2320  O  O    . PHE   A 1 148 ? 8.361   3.112   28.188  1.00 32.54  ?  147 PHE   B O    1 
ATOM   2321  C  CB   . PHE   A 1 148 ? 5.622   1.132   28.241  1.00 33.97  ?  147 PHE   B CB   1 
ATOM   2322  C  CG   . PHE   A 1 148 ? 5.142   2.150   29.254  1.00 43.08  ?  147 PHE   B CG   1 
ATOM   2323  C  CD1  . PHE   A 1 148 ? 4.468   3.300   28.846  1.00 37.44  ?  147 PHE   B CD1  1 
ATOM   2324  C  CD2  . PHE   A 1 148 ? 5.348   1.948   30.623  1.00 40.52  ?  147 PHE   B CD2  1 
ATOM   2325  C  CE1  . PHE   A 1 148 ? 4.028   4.225   29.760  1.00 36.06  ?  147 PHE   B CE1  1 
ATOM   2326  C  CE2  . PHE   A 1 148 ? 4.867   2.871   31.538  1.00 47.27  ?  147 PHE   B CE2  1 
ATOM   2327  C  CZ   . PHE   A 1 148 ? 4.218   4.016   31.097  1.00 45.32  ?  147 PHE   B CZ   1 
ATOM   2328  H  H    . PHE   A 1 148 ? 6.436   -0.020  26.278  1.00 38.28  ?  147 PHE   B H    1 
ATOM   2329  H  HA   . PHE   A 1 148 ? 6.353   2.514   26.925  1.00 42.52  ?  147 PHE   B HA   1 
ATOM   2330  H  HB2  . PHE   A 1 148 ? 4.852   0.838   27.730  1.00 40.76  ?  147 PHE   B HB2  1 
ATOM   2331  H  HB3  . PHE   A 1 148 ? 6.001   0.385   28.730  1.00 40.76  ?  147 PHE   B HB3  1 
ATOM   2332  H  HD1  . PHE   A 1 148 ? 4.315   3.444   27.940  1.00 44.93  ?  147 PHE   B HD1  1 
ATOM   2333  H  HD2  . PHE   A 1 148 ? 5.807   1.195   30.919  1.00 48.63  ?  147 PHE   B HD2  1 
ATOM   2334  H  HE1  . PHE   A 1 148 ? 3.599   4.996   29.468  1.00 43.27  ?  147 PHE   B HE1  1 
ATOM   2335  H  HE2  . PHE   A 1 148 ? 4.980   2.724   32.449  1.00 56.73  ?  147 PHE   B HE2  1 
ATOM   2336  H  HZ   . PHE   A 1 148 ? 3.912   4.642   31.712  1.00 54.38  ?  147 PHE   B HZ   1 
ATOM   2337  N  N    . CYS   A 1 149 ? 8.734   0.889   28.343  1.00 30.27  ?  148 CYS   B N    1 
ATOM   2338  C  CA   . CYS   A 1 149 ? 10.032  1.051   28.977  1.00 30.83  ?  148 CYS   B CA   1 
ATOM   2339  C  C    . CYS   A 1 149 ? 10.981  1.855   28.111  1.00 40.11  ?  148 CYS   B C    1 
ATOM   2340  O  O    . CYS   A 1 149 ? 11.667  2.753   28.612  1.00 33.83  ?  148 CYS   B O    1 
ATOM   2341  C  CB   . CYS   A 1 149 ? 10.613  -0.313  29.267  1.00 32.91  ?  148 CYS   B CB   1 
ATOM   2342  S  SG   . CYS   A 1 149 ? 9.675   -1.014  30.628  1.00 39.97  ?  148 CYS   B SG   1 
ATOM   2343  H  H    . CYS   A 1 149 ? 8.504   0.070   28.221  1.00 36.32  ?  148 CYS   B H    1 
ATOM   2344  H  HA   . CYS   A 1 149 ? 9.920   1.531   29.813  1.00 37.00  ?  148 CYS   B HA   1 
ATOM   2345  H  HB2  . CYS   A 1 149 ? 10.530  -0.887  28.489  1.00 39.49  ?  148 CYS   B HB2  1 
ATOM   2346  H  HB3  . CYS   A 1 149 ? 11.545  -0.235  29.523  1.00 39.49  ?  148 CYS   B HB3  1 
ATOM   2347  H  HG   . CYS   A 1 149 ? 10.005  -2.157  30.782  1.00 47.96  ?  148 CYS   B HG   1 
ATOM   2348  N  N    . ALA   A 1 150 ? 11.006  1.594   26.805  1.00 37.16  ?  149 ALA   B N    1 
ATOM   2349  C  CA   . ALA   A 1 150 ? 11.873  2.386   25.942  1.00 36.46  ?  149 ALA   B CA   1 
ATOM   2350  C  C    . ALA   A 1 150 ? 11.468  3.853   25.951  1.00 29.58  ?  149 ALA   B C    1 
ATOM   2351  O  O    . ALA   A 1 150 ? 12.320  4.751   25.956  1.00 32.48  ?  149 ALA   B O    1 
ATOM   2352  C  CB   . ALA   A 1 150 ? 11.816  1.830   24.525  1.00 38.43  ?  149 ALA   B CB   1 
ATOM   2353  H  H    . ALA   A 1 150 ? 10.547  0.984   26.409  1.00 44.60  ?  149 ALA   B H    1 
ATOM   2354  H  HA   . ALA   A 1 150 ? 12.786  2.327   26.265  1.00 43.76  ?  149 ALA   B HA   1 
ATOM   2355  H  HB1  . ALA   A 1 150 ? 12.436  2.325   23.967  1.00 46.12  ?  149 ALA   B HB1  1 
ATOM   2356  H  HB2  . ALA   A 1 150 ? 12.062  0.892   24.544  1.00 46.12  ?  149 ALA   B HB2  1 
ATOM   2357  H  HB3  . ALA   A 1 150 ? 10.913  1.928   24.184  1.00 46.12  ?  149 ALA   B HB3  1 
ATOM   2358  N  N    . LEU   A 1 151 ? 10.163  4.118   25.921  1.00 32.16  ?  150 LEU   B N    1 
ATOM   2359  C  CA   . LEU   A 1 151 ? 9.693   5.506   25.876  1.00 41.37  ?  150 LEU   B CA   1 
ATOM   2360  C  C    . LEU   A 1 151 ? 10.091  6.257   27.143  1.00 33.81  ?  150 LEU   B C    1 
ATOM   2361  O  O    . LEU   A 1 151 ? 10.409  7.443   27.106  1.00 36.17  ?  150 LEU   B O    1 
ATOM   2362  C  CB   . LEU   A 1 151 ? 8.160   5.549   25.688  1.00 38.13  ?  150 LEU   B CB   1 
ATOM   2363  C  CG   . LEU   A 1 151 ? 7.594   5.256   24.291  1.00 36.28  ?  150 LEU   B CG   1 
ATOM   2364  C  CD1  . LEU   A 1 151 ? 6.049   5.396   24.204  1.00 39.16  ?  150 LEU   B CD1  1 
ATOM   2365  C  CD2  . LEU   A 1 151 ? 8.282   6.199   23.297  1.00 40.51  ?  150 LEU   B CD2  1 
ATOM   2366  H  H    . LEU   A 1 151 ? 9.539   3.527   25.926  1.00 38.59  ?  150 LEU   B H    1 
ATOM   2367  H  HA   . LEU   A 1 151 ? 10.101  5.948   25.115  1.00 49.64  ?  150 LEU   B HA   1 
ATOM   2368  H  HB2  . LEU   A 1 151 ? 7.772   4.893   26.288  1.00 45.76  ?  150 LEU   B HB2  1 
ATOM   2369  H  HB3  . LEU   A 1 151 ? 7.858   6.438   25.929  1.00 45.76  ?  150 LEU   B HB3  1 
ATOM   2370  H  HG   . LEU   A 1 151 ? 7.773   4.329   24.069  1.00 43.53  ?  150 LEU   B HG   1 
ATOM   2371  H  HD11 . LEU   A 1 151 ? 5.745   5.023   23.362  1.00 46.99  ?  150 LEU   B HD11 1 
ATOM   2372  H  HD12 . LEU   A 1 151 ? 5.647   4.915   24.944  1.00 46.99  ?  150 LEU   B HD12 1 
ATOM   2373  H  HD13 . LEU   A 1 151 ? 5.814   6.336   24.254  1.00 46.99  ?  150 LEU   B HD13 1 
ATOM   2374  H  HD21 . LEU   A 1 151 ? 7.731   6.277   22.503  1.00 48.61  ?  150 LEU   B HD21 1 
ATOM   2375  H  HD22 . LEU   A 1 151 ? 8.391   7.070   23.711  1.00 48.61  ?  150 LEU   B HD22 1 
ATOM   2376  H  HD23 . LEU   A 1 151 ? 9.150   5.833   23.063  1.00 48.61  ?  150 LEU   B HD23 1 
ATOM   2377  N  N    . ILE   A 1 152 ? 10.063  5.582   28.285  1.00 34.21  ?  151 ILE   B N    1 
ATOM   2378  C  CA   . ILE   A 1 152 ? 10.471  6.234   29.524  1.00 35.97  ?  151 ILE   B CA   1 
ATOM   2379  C  C    . ILE   A 1 152 ? 11.933  6.646   29.456  1.00 33.81  ?  151 ILE   B C    1 
ATOM   2380  O  O    . ILE   A 1 152 ? 12.292  7.778   29.798  1.00 32.08  ?  151 ILE   B O    1 
ATOM   2381  C  CB   . ILE   A 1 152 ? 10.206  5.322   30.730  1.00 37.56  ?  151 ILE   B CB   1 
ATOM   2382  C  CG1  . ILE   A 1 152 ? 8.719   5.327   31.025  1.00 34.74  ?  151 ILE   B CG1  1 
ATOM   2383  C  CG2  . ILE   A 1 152 ? 10.992  5.801   31.945  1.00 36.52  ?  151 ILE   B CG2  1 
ATOM   2384  C  CD1  . ILE   A 1 152 ? 8.219   3.928   31.322  1.00 37.83  ?  151 ILE   B CD1  1 
ATOM   2385  H  H    . ILE   A 1 152 ? 9.818   4.762   28.370  1.00 41.06  ?  151 ILE   B H    1 
ATOM   2386  H  HA   . ILE   A 1 152 ? 9.938   7.038   29.631  1.00 43.17  ?  151 ILE   B HA   1 
ATOM   2387  H  HB   . ILE   A 1 152 ? 10.495  4.420   30.523  1.00 45.08  ?  151 ILE   B HB   1 
ATOM   2388  H  HG12 . ILE   A 1 152 ? 8.545   5.887   31.799  1.00 41.69  ?  151 ILE   B HG12 1 
ATOM   2389  H  HG13 . ILE   A 1 152 ? 8.238   5.669   30.255  1.00 41.69  ?  151 ILE   B HG13 1 
ATOM   2390  H  HG21 . ILE   A 1 152 ? 10.589  5.433   32.747  1.00 43.83  ?  151 ILE   B HG21 1 
ATOM   2391  H  HG22 . ILE   A 1 152 ? 11.910  5.498   31.867  1.00 43.83  ?  151 ILE   B HG22 1 
ATOM   2392  H  HG23 . ILE   A 1 152 ? 10.965  6.770   31.976  1.00 43.83  ?  151 ILE   B HG23 1 
ATOM   2393  H  HD11 . ILE   A 1 152 ? 7.288   3.975   31.588  1.00 45.40  ?  151 ILE   B HD11 1 
ATOM   2394  H  HD12 . ILE   A 1 152 ? 8.308   3.385   30.524  1.00 45.40  ?  151 ILE   B HD12 1 
ATOM   2395  H  HD13 . ILE   A 1 152 ? 8.750   3.550   32.041  1.00 45.40  ?  151 ILE   B HD13 1 
ATOM   2396  N  N    . LEU   A 1 153 ? 12.797  5.722   29.045  1.00 32.02  ?  152 LEU   B N    1 
ATOM   2397  C  CA   . LEU   A 1 153 ? 14.198  6.066   28.870  1.00 35.99  ?  152 LEU   B CA   1 
ATOM   2398  C  C    . LEU   A 1 153 ? 14.356  7.251   27.922  1.00 40.31  ?  152 LEU   B C    1 
ATOM   2399  O  O    . LEU   A 1 153 ? 15.115  8.171   28.215  1.00 39.99  ?  152 LEU   B O    1 
ATOM   2400  C  CB   . LEU   A 1 153 ? 14.974  4.845   28.372  1.00 36.30  ?  152 LEU   B CB   1 
ATOM   2401  C  CG   . LEU   A 1 153 ? 14.915  3.685   29.383  1.00 37.13  ?  152 LEU   B CG   1 
ATOM   2402  C  CD1  . LEU   A 1 153 ? 15.058  2.279   28.856  1.00 33.30  ?  152 LEU   B CD1  1 
ATOM   2403  C  CD2  . LEU   A 1 153 ? 16.082  3.996   30.396  1.00 36.90  ?  152 LEU   B CD2  1 
ATOM   2404  H  H    . LEU   A 1 153 ? 12.599  4.905   28.864  1.00 38.43  ?  152 LEU   B H    1 
ATOM   2405  H  HA   . LEU   A 1 153 ? 14.577  6.323   29.725  1.00 43.19  ?  152 LEU   B HA   1 
ATOM   2406  H  HB2  . LEU   A 1 153 ? 14.589  4.541   27.535  1.00 43.56  ?  152 LEU   B HB2  1 
ATOM   2407  H  HB3  . LEU   A 1 153 ? 15.903  5.089   28.241  1.00 43.56  ?  152 LEU   B HB3  1 
ATOM   2408  H  HG   . LEU   A 1 153 ? 14.022  3.658   29.761  1.00 44.56  ?  152 LEU   B HG   1 
ATOM   2409  H  HD11 . LEU   A 1 153 ? 14.653  1.663   29.486  1.00 39.96  ?  152 LEU   B HD11 1 
ATOM   2410  H  HD12 . LEU   A 1 153 ? 14.611  2.217   27.997  1.00 39.96  ?  152 LEU   B HD12 1 
ATOM   2411  H  HD13 . LEU   A 1 153 ? 16.001  2.075   28.753  1.00 39.96  ?  152 LEU   B HD13 1 
ATOM   2412  H  HD21 . LEU   A 1 153 ? 16.203  3.232   30.982  1.00 44.28  ?  152 LEU   B HD21 1 
ATOM   2413  H  HD22 . LEU   A 1 153 ? 16.897  4.164   29.898  1.00 44.28  ?  152 LEU   B HD22 1 
ATOM   2414  H  HD23 . LEU   A 1 153 ? 15.846  4.779   30.919  1.00 44.28  ?  152 LEU   B HD23 1 
ATOM   2415  N  N    . ALA   A 1 154 ? 13.606  7.286   26.807  1.00 38.47  ?  153 ALA   B N    1 
ATOM   2416  C  CA   . ALA   A 1 154 ? 13.771  8.403   25.876  1.00 36.24  ?  153 ALA   B CA   1 
ATOM   2417  C  C    . ALA   A 1 154 ? 13.231  9.694   26.463  1.00 34.20  ?  153 ALA   B C    1 
ATOM   2418  O  O    . ALA   A 1 154 ? 13.822  10.761  26.289  1.00 35.26  ?  153 ALA   B O    1 
ATOM   2419  C  CB   . ALA   A 1 154 ? 13.082  8.093   24.541  1.00 39.80  ?  153 ALA   B CB   1 
ATOM   2420  H  H    . ALA   A 1 154 ? 13.021  6.699   26.580  1.00 46.16  ?  153 ALA   B H    1 
ATOM   2421  H  HA   . ALA   A 1 154 ? 14.718  8.521   25.703  1.00 43.49  ?  153 ALA   B HA   1 
ATOM   2422  H  HB1  . ALA   A 1 154 ? 13.200  8.847   23.942  1.00 47.76  ?  153 ALA   B HB1  1 
ATOM   2423  H  HB2  . ALA   A 1 154 ? 13.484  7.299   24.155  1.00 47.76  ?  153 ALA   B HB2  1 
ATOM   2424  H  HB3  . ALA   A 1 154 ? 12.138  7.941   24.700  1.00 47.76  ?  153 ALA   B HB3  1 
ATOM   2425  N  N    . TYR   A 1 155 ? 12.076  9.635   27.116  1.00 32.82  ?  154 TYR   B N    1 
ATOM   2426  C  CA   . TYR   A 1 155 ? 11.542  10.862  27.695  1.00 37.97  ?  154 TYR   B CA   1 
ATOM   2427  C  C    . TYR   A 1 155 ? 12.447  11.408  28.784  1.00 47.96  ?  154 TYR   B C    1 
ATOM   2428  O  O    . TYR   A 1 155 ? 12.407  12.615  29.057  1.00 50.63  ?  154 TYR   B O    1 
ATOM   2429  C  CB   . TYR   A 1 155 ? 10.150  10.629  28.252  1.00 37.09  ?  154 TYR   B CB   1 
ATOM   2430  C  CG   . TYR   A 1 155 ? 9.084   10.730  27.203  1.00 32.47  ?  154 TYR   B CG   1 
ATOM   2431  C  CD1  . TYR   A 1 155 ? 8.839   11.915  26.546  1.00 37.78  ?  154 TYR   B CD1  1 
ATOM   2432  C  CD2  . TYR   A 1 155 ? 8.342   9.632   26.855  1.00 35.95  ?  154 TYR   B CD2  1 
ATOM   2433  C  CE1  . TYR   A 1 155 ? 7.877   12.005  25.561  1.00 40.53  ?  154 TYR   B CE1  1 
ATOM   2434  C  CE2  . TYR   A 1 155 ? 7.366   9.703   25.901  1.00 37.64  ?  154 TYR   B CE2  1 
ATOM   2435  C  CZ   . TYR   A 1 155 ? 7.128   10.888  25.245  1.00 40.50  ?  154 TYR   B CZ   1 
ATOM   2436  O  OH   . TYR   A 1 155 ? 6.125   10.928  24.304  1.00 41.09  ?  154 TYR   B OH   1 
ATOM   2437  H  H    . TYR   A 1 155 ? 11.602  8.928   27.234  1.00 39.38  ?  154 TYR   B H    1 
ATOM   2438  H  HA   . TYR   A 1 155 ? 11.465  11.528  26.994  1.00 45.56  ?  154 TYR   B HA   1 
ATOM   2439  H  HB2  . TYR   A 1 155 ? 10.108  9.740   28.639  1.00 44.51  ?  154 TYR   B HB2  1 
ATOM   2440  H  HB3  . TYR   A 1 155 ? 9.966   11.295  28.932  1.00 44.51  ?  154 TYR   B HB3  1 
ATOM   2441  H  HD1  . TYR   A 1 155 ? 9.333   12.670  26.771  1.00 45.33  ?  154 TYR   B HD1  1 
ATOM   2442  H  HD2  . TYR   A 1 155 ? 8.506   8.820   27.277  1.00 43.14  ?  154 TYR   B HD2  1 
ATOM   2443  H  HE1  . TYR   A 1 155 ? 7.734   12.808  25.115  1.00 48.63  ?  154 TYR   B HE1  1 
ATOM   2444  H  HE2  . TYR   A 1 155 ? 6.862   8.949   25.695  1.00 45.17  ?  154 TYR   B HE2  1 
ATOM   2445  H  HH   . TYR   A 1 155 ? 6.029   11.712  24.018  1.00 49.31  ?  154 TYR   B HH   1 
ATOM   2446  N  N    . CYS   A 1 156 ? 13.272  10.544  29.393  1.00 41.52  ?  155 CYS   B N    1 
ATOM   2447  C  CA   . CYS   A 1 156 ? 14.061  10.908  30.547  1.00 44.59  ?  155 CYS   B CA   1 
ATOM   2448  C  C    . CYS   A 1 156 ? 15.526  11.105  30.213  1.00 50.72  ?  155 CYS   B C    1 
ATOM   2449  O  O    . CYS   A 1 156 ? 16.305  11.407  31.112  1.00 56.11  ?  155 CYS   B O    1 
ATOM   2450  C  CB   . CYS   A 1 156 ? 13.918  9.833   31.633  1.00 44.34  ?  155 CYS   B CB   1 
ATOM   2451  S  SG   . CYS   A 1 156 ? 12.304  9.761   32.490  1.00 44.64  ?  155 CYS   B SG   1 
ATOM   2452  H  H    . CYS   A 1 156 ? 13.384  9.730   29.141  1.00 49.82  ?  155 CYS   B H    1 
ATOM   2453  H  HA   . CYS   A 1 156 ? 13.725  11.744  30.907  1.00 53.51  ?  155 CYS   B HA   1 
ATOM   2454  H  HB2  . CYS   A 1 156 ? 14.062  8.966   31.222  1.00 53.20  ?  155 CYS   B HB2  1 
ATOM   2455  H  HB3  . CYS   A 1 156 ? 14.593  9.995   32.310  1.00 53.20  ?  155 CYS   B HB3  1 
ATOM   2456  H  HG   . CYS   A 1 156 ? 12.242  8.743   33.122  1.00 53.57  ?  155 CYS   B HG   1 
ATOM   2457  N  N    . ASN   A 1 157 ? 15.926  10.913  28.959  1.00 47.04  ?  156 ASN   B N    1 
ATOM   2458  C  CA   . ASN   A 1 157 ? 17.313  11.064  28.552  1.00 45.25  ?  156 ASN   B CA   1 
ATOM   2459  C  C    . ASN   A 1 157 ? 18.212  10.117  29.326  1.00 45.19  ?  156 ASN   B C    1 
ATOM   2460  O  O    . ASN   A 1 157 ? 19.283  10.494  29.776  1.00 44.38  ?  156 ASN   B O    1 
ATOM   2461  C  CB   . ASN   A 1 157 ? 17.796  12.496  28.740  1.00 50.68  ?  156 ASN   B CB   1 
ATOM   2462  C  CG   . ASN   A 1 157 ? 17.341  13.392  27.641  1.00 58.77  ?  156 ASN   B CG   1 
ATOM   2463  O  OD1  . ASN   A 1 157 ? 17.938  13.420  26.547  1.00 61.73  ?  156 ASN   B OD1  1 
ATOM   2464  N  ND2  . ASN   A 1 157 ? 16.276  14.152  27.912  1.00 49.60  ?  156 ASN   B ND2  1 
ATOM   2465  H  H    . ASN   A 1 157 ? 15.400  10.691  28.316  1.00 56.45  ?  156 ASN   B H    1 
ATOM   2466  H  HA   . ASN   A 1 157 ? 17.372  10.843  27.609  1.00 54.30  ?  156 ASN   B HA   1 
ATOM   2467  H  HB2  . ASN   A 1 157 ? 17.447  12.841  29.576  1.00 60.82  ?  156 ASN   B HB2  1 
ATOM   2468  H  HB3  . ASN   A 1 157 ? 18.766  12.505  28.756  1.00 60.82  ?  156 ASN   B HB3  1 
ATOM   2469  H  HD21 . ASN   A 1 157 ? 15.898  14.103  28.683  1.00 59.53  ?  156 ASN   B HD21 1 
ATOM   2470  H  HD22 . ASN   A 1 157 ? 15.968  14.689  27.316  1.00 59.53  ?  156 ASN   B HD22 1 
ATOM   2471  N  N    . LYS   A 1 158 ? 17.752  8.906   29.542  1.00 40.82  ?  157 LYS   B N    1 
ATOM   2472  C  CA   . LYS   A 1 158 ? 18.532  7.883   30.204  1.00 43.62  ?  157 LYS   B CA   1 
ATOM   2473  C  C    . LYS   A 1 158 ? 18.708  6.724   29.238  1.00 43.35  ?  157 LYS   B C    1 
ATOM   2474  O  O    . LYS   A 1 158 ? 17.832  6.435   28.415  1.00 50.14  ?  157 LYS   B O    1 
ATOM   2475  C  CB   . LYS   A 1 158 ? 17.871  7.400   31.516  1.00 47.80  ?  157 LYS   B CB   1 
ATOM   2476  C  CG   . LYS   A 1 158 ? 17.504  8.543   32.468  1.00 49.62  ?  157 LYS   B CG   1 
ATOM   2477  C  CD   . LYS   A 1 158 ? 18.651  8.931   33.376  1.00 53.29  ?  157 LYS   B CD   1 
ATOM   2478  C  CE   . LYS   A 1 158 ? 18.997  7.787   34.353  1.00 56.57  ?  157 LYS   B CE   1 
ATOM   2479  N  NZ   . LYS   A 1 158 ? 19.662  8.243   35.628  1.00 56.94  ?  157 LYS   B NZ   1 
ATOM   2480  H  H    . LYS   A 1 158 ? 16.968  8.643   29.307  1.00 48.99  ?  157 LYS   B H    1 
ATOM   2481  H  HA   . LYS   A 1 158 ? 19.404  8.231   30.449  1.00 52.34  ?  157 LYS   B HA   1 
ATOM   2482  H  HB2  . LYS   A 1 158 ? 17.056  6.920   31.298  1.00 57.36  ?  157 LYS   B HB2  1 
ATOM   2483  H  HB3  . LYS   A 1 158 ? 18.488  6.812   31.980  1.00 57.36  ?  157 LYS   B HB3  1 
ATOM   2484  H  HG2  . LYS   A 1 158 ? 17.255  9.322   31.947  1.00 59.54  ?  157 LYS   B HG2  1 
ATOM   2485  H  HG3  . LYS   A 1 158 ? 16.760  8.265   33.025  1.00 59.54  ?  157 LYS   B HG3  1 
ATOM   2486  H  HD2  . LYS   A 1 158 ? 19.435  9.124   32.840  1.00 63.94  ?  157 LYS   B HD2  1 
ATOM   2487  H  HD3  . LYS   A 1 158 ? 18.402  9.712   33.895  1.00 63.94  ?  157 LYS   B HD3  1 
ATOM   2488  H  HE2  . LYS   A 1 158 ? 18.179  7.328   34.597  1.00 67.88  ?  157 LYS   B HE2  1 
ATOM   2489  H  HE3  . LYS   A 1 158 ? 19.603  7.173   33.910  1.00 67.88  ?  157 LYS   B HE3  1 
ATOM   2490  H  HZ1  . LYS   A 1 158 ? 19.846  7.541   36.143  1.00 68.33  ?  157 LYS   B HZ1  1 
ATOM   2491  H  HZ2  . LYS   A 1 158 ? 20.419  8.670   35.440  1.00 68.33  ?  157 LYS   B HZ2  1 
ATOM   2492  H  HZ3  . LYS   A 1 158 ? 19.122  8.793   36.072  1.00 68.33  ?  157 LYS   B HZ3  1 
ATOM   2493  N  N    . THR   A 1 159 ? 19.858  6.085   29.329  1.00 46.47  ?  158 THR   B N    1 
ATOM   2494  C  CA   . THR   A 1 159 ? 20.220  4.995   28.445  1.00 53.08  ?  158 THR   B CA   1 
ATOM   2495  C  C    . THR   A 1 159 ? 20.093  3.672   29.186  1.00 45.40  ?  158 THR   B C    1 
ATOM   2496  O  O    . THR   A 1 159 ? 20.107  3.616   30.419  1.00 37.45  ?  158 THR   B O    1 
ATOM   2497  C  CB   . THR   A 1 159 ? 21.659  5.157   27.924  1.00 50.53  ?  158 THR   B CB   1 
ATOM   2498  O  OG1  . THR   A 1 159 ? 22.533  5.368   29.036  1.00 51.60  ?  158 THR   B OG1  1 
ATOM   2499  C  CG2  . THR   A 1 159 ? 21.747  6.332   26.944  1.00 51.36  ?  158 THR   B CG2  1 
ATOM   2500  H  H    . THR   A 1 159 ? 20.463  6.269   29.912  1.00 55.76  ?  158 THR   B H    1 
ATOM   2501  H  HA   . THR   A 1 159 ? 19.626  4.991   27.678  1.00 63.69  ?  158 THR   B HA   1 
ATOM   2502  H  HB   . THR   A 1 159 ? 21.936  4.359   27.447  1.00 60.64  ?  158 THR   B HB   1 
ATOM   2503  H  HG1  . THR   A 1 159 ? 23.327  5.429   28.770  1.00 61.92  ?  158 THR   B HG1  1 
ATOM   2504  H  HG21 . THR   A 1 159 ? 22.608  6.326   26.496  1.00 61.63  ?  158 THR   B HG21 1 
ATOM   2505  H  HG22 . THR   A 1 159 ? 21.046  6.261   26.278  1.00 61.63  ?  158 THR   B HG22 1 
ATOM   2506  H  HG23 . THR   A 1 159 ? 21.646  7.170   27.421  1.00 61.63  ?  158 THR   B HG23 1 
ATOM   2507  N  N    . VAL   A 1 160 ? 19.997  2.601   28.393  1.00 42.51  ?  159 VAL   B N    1 
ATOM   2508  C  CA   . VAL   A 1 160 ? 19.977  1.251   28.921  1.00 39.57  ?  159 VAL   B CA   1 
ATOM   2509  C  C    . VAL   A 1 160 ? 21.229  1.003   29.742  1.00 40.94  ?  159 VAL   B C    1 
ATOM   2510  O  O    . VAL   A 1 160 ? 22.352  1.341   29.331  1.00 40.28  ?  159 VAL   B O    1 
ATOM   2511  C  CB   . VAL   A 1 160 ? 19.815  0.256   27.766  1.00 36.80  ?  159 VAL   B CB   1 
ATOM   2512  C  CG1  . VAL   A 1 160 ? 19.957  -1.172  28.242  1.00 39.20  ?  159 VAL   B CG1  1 
ATOM   2513  C  CG2  . VAL   A 1 160 ? 18.414  0.474   27.093  1.00 42.32  ?  159 VAL   B CG2  1 
ATOM   2514  H  H    . VAL   A 1 160 ? 19.942  2.637   27.536  1.00 51.01  ?  159 VAL   B H    1 
ATOM   2515  H  HA   . VAL   A 1 160 ? 19.222  1.140   29.520  1.00 47.48  ?  159 VAL   B HA   1 
ATOM   2516  H  HB   . VAL   A 1 160 ? 20.516  0.411   27.114  1.00 44.15  ?  159 VAL   B HB   1 
ATOM   2517  H  HG11 . VAL   A 1 160 ? 19.842  -1.769  27.486  1.00 47.04  ?  159 VAL   B HG11 1 
ATOM   2518  H  HG12 . VAL   A 1 160 ? 20.839  -1.291  28.627  1.00 47.04  ?  159 VAL   B HG12 1 
ATOM   2519  H  HG13 . VAL   A 1 160 ? 19.277  -1.351  28.911  1.00 47.04  ?  159 VAL   B HG13 1 
ATOM   2520  H  HG21 . VAL   A 1 160 ? 18.203  -0.298  26.546  1.00 50.79  ?  159 VAL   B HG21 1 
ATOM   2521  H  HG22 . VAL   A 1 160 ? 17.744  0.581   27.786  1.00 50.79  ?  159 VAL   B HG22 1 
ATOM   2522  H  HG23 . VAL   A 1 160 ? 18.449  1.271   26.542  1.00 50.79  ?  159 VAL   B HG23 1 
ATOM   2523  N  N    . GLY   A 1 161 ? 21.022  0.437   30.943  1.00 34.10  ?  160 GLY   B N    1 
ATOM   2524  C  CA   . GLY   A 1 161 ? 22.099  0.055   31.843  1.00 37.59  ?  160 GLY   B CA   1 
ATOM   2525  C  C    . GLY   A 1 161 ? 22.427  1.041   32.953  1.00 32.52  ?  160 GLY   B C    1 
ATOM   2526  O  O    . GLY   A 1 161 ? 23.140  0.680   33.898  1.00 36.84  ?  160 GLY   B O    1 
ATOM   2527  H  H    . GLY   A 1 161 ? 20.241  0.265   31.259  1.00 40.92  ?  160 GLY   B H    1 
ATOM   2528  H  HA2  . GLY   A 1 161 ? 21.861  -0.786  32.263  1.00 45.10  ?  160 GLY   B HA2  1 
ATOM   2529  H  HA3  . GLY   A 1 161 ? 22.905  -0.070  31.319  1.00 45.10  ?  160 GLY   B HA3  1 
ATOM   2530  N  N    . GLU   A 1 162 ? 21.979  2.270   32.849  1.00 32.21  ?  161 GLU   B N    1 
ATOM   2531  C  CA   . GLU   A 1 162 ? 22.154  3.262   33.894  1.00 34.22  ?  161 GLU   B CA   1 
ATOM   2532  C  C    . GLU   A 1 162 ? 21.004  3.144   34.912  1.00 37.75  ?  161 GLU   B C    1 
ATOM   2533  O  O    . GLU   A 1 162 ? 19.825  3.103   34.534  1.00 31.68  ?  161 GLU   B O    1 
ATOM   2534  C  CB   . GLU   A 1 162 ? 22.179  4.631   33.223  1.00 35.79  ?  161 GLU   B CB   1 
ATOM   2535  C  CG   . GLU   A 1 162 ? 22.473  5.822   34.077  1.00 45.70  ?  161 GLU   B CG   1 
ATOM   2536  C  CD   . GLU   A 1 162 ? 22.298  7.128   33.258  1.00 56.77  ?  161 GLU   B CD   1 
ATOM   2537  O  OE1  . GLU   A 1 162 ? 22.450  8.207   33.876  1.00 53.65  ?  161 GLU   B OE1  1 
ATOM   2538  O  OE2  . GLU   A 1 162 ? 21.979  7.059   32.016  1.00 57.22  -1 161 GLU   B OE2  1 
ATOM   2539  H  H    . GLU   A 1 162 ? 21.556  2.569   32.163  1.00 38.65  ?  161 GLU   B H    1 
ATOM   2540  H  HA   . GLU   A 1 162 ? 22.977  3.133   34.391  1.00 41.07  ?  161 GLU   B HA   1 
ATOM   2541  H  HB2  . GLU   A 1 162 ? 22.859  4.609   32.531  1.00 42.95  ?  161 GLU   B HB2  1 
ATOM   2542  H  HB3  . GLU   A 1 162 ? 21.307  4.781   32.825  1.00 42.95  ?  161 GLU   B HB3  1 
ATOM   2543  H  HG2  . GLU   A 1 162 ? 21.860  5.843   34.828  1.00 54.83  ?  161 GLU   B HG2  1 
ATOM   2544  H  HG3  . GLU   A 1 162 ? 23.387  5.776   34.396  1.00 54.83  ?  161 GLU   B HG3  1 
ATOM   2545  N  N    . LEU   A 1 163 ? 21.345  3.085   36.201  1.00 25.69  ?  162 LEU   B N    1 
ATOM   2546  C  CA   . LEU   A 1 163 ? 20.346  3.098   37.253  1.00 28.55  ?  162 LEU   B CA   1 
ATOM   2547  C  C    . LEU   A 1 163 ? 19.828  4.525   37.408  1.00 32.48  ?  162 LEU   B C    1 
ATOM   2548  O  O    . LEU   A 1 163 ? 20.628  5.473   37.503  1.00 28.84  ?  162 LEU   B O    1 
ATOM   2549  C  CB   . LEU   A 1 163 ? 20.936  2.556   38.559  1.00 29.99  ?  162 LEU   B CB   1 
ATOM   2550  C  CG   . LEU   A 1 163 ? 19.956  2.533   39.722  1.00 27.33  ?  162 LEU   B CG   1 
ATOM   2551  C  CD1  . LEU   A 1 163 ? 18.923  1.395   39.612  1.00 31.44  ?  162 LEU   B CD1  1 
ATOM   2552  C  CD2  . LEU   A 1 163 ? 20.629  2.419   41.076  1.00 29.24  ?  162 LEU   B CD2  1 
ATOM   2553  H  H    . LEU   A 1 163 ? 22.155  3.037   36.488  1.00 30.83  ?  162 LEU   B H    1 
ATOM   2554  H  HA   . LEU   A 1 163 ? 19.597  2.523   37.031  1.00 34.26  ?  162 LEU   B HA   1 
ATOM   2555  H  HB2  . LEU   A 1 163 ? 21.237  1.646   38.408  1.00 35.98  ?  162 LEU   B HB2  1 
ATOM   2556  H  HB3  . LEU   A 1 163 ? 21.685  3.115   38.815  1.00 35.98  ?  162 LEU   B HB3  1 
ATOM   2557  H  HG   . LEU   A 1 163 ? 19.502  3.388   39.669  1.00 32.79  ?  162 LEU   B HG   1 
ATOM   2558  H  HD11 . LEU   A 1 163 ? 18.451  1.314   40.456  1.00 37.73  ?  162 LEU   B HD11 1 
ATOM   2559  H  HD12 . LEU   A 1 163 ? 18.296  1.605   38.902  1.00 37.73  ?  162 LEU   B HD12 1 
ATOM   2560  H  HD13 . LEU   A 1 163 ? 19.385  0.567   39.411  1.00 37.73  ?  162 LEU   B HD13 1 
ATOM   2561  H  HD21 . LEU   A 1 163 ? 19.948  2.405   41.767  1.00 35.09  ?  162 LEU   B HD21 1 
ATOM   2562  H  HD22 . LEU   A 1 163 ? 21.146  1.599   41.104  1.00 35.09  ?  162 LEU   B HD22 1 
ATOM   2563  H  HD23 . LEU   A 1 163 ? 21.213  3.183   41.203  1.00 35.09  ?  162 LEU   B HD23 1 
ATOM   2564  N  N    . GLY   A 1 164 ? 18.489  4.668   37.410  1.00 27.54  ?  163 GLY   B N    1 
ATOM   2565  C  CA   . GLY   A 1 164 ? 17.829  5.947   37.580  1.00 31.51  ?  163 GLY   B CA   1 
ATOM   2566  C  C    . GLY   A 1 164 ? 16.989  6.005   38.854  1.00 27.61  ?  163 GLY   B C    1 
ATOM   2567  O  O    . GLY   A 1 164 ? 16.844  5.021   39.573  1.00 24.24  ?  163 GLY   B O    1 
ATOM   2568  H  H    . GLY   A 1 164 ? 17.939  4.014   37.312  1.00 33.04  ?  163 GLY   B H    1 
ATOM   2569  H  HA2  . GLY   A 1 164 ? 18.497  6.649   37.622  1.00 37.82  ?  163 GLY   B HA2  1 
ATOM   2570  H  HA3  . GLY   A 1 164 ? 17.247  6.110   36.822  1.00 37.82  ?  163 GLY   B HA3  1 
ATOM   2571  N  N    . ASP   A 1 165 ? 16.470  7.202   39.137  1.00 28.31  ?  164 ASP   B N    1 
ATOM   2572  C  CA   . ASP   A 1 165 ? 15.758  7.504   40.374  1.00 32.49  ?  164 ASP   B CA   1 
ATOM   2573  C  C    . ASP   A 1 165 ? 14.243  7.410   40.145  1.00 30.56  ?  164 ASP   B C    1 
ATOM   2574  O  O    . ASP   A 1 165 ? 13.676  8.109   39.283  1.00 29.27  ?  164 ASP   B O    1 
ATOM   2575  C  CB   . ASP   A 1 165 ? 16.143  8.894   40.892  1.00 29.70  ?  164 ASP   B CB   1 
ATOM   2576  C  CG   . ASP   A 1 165 ? 15.511  9.206   42.241  1.00 35.79  ?  164 ASP   B CG   1 
ATOM   2577  O  OD1  . ASP   A 1 165 ? 14.279  9.060   42.345  1.00 35.19  ?  164 ASP   B OD1  1 
ATOM   2578  O  OD2  . ASP   A 1 165 ? 16.241  9.538   43.202  1.00 35.65  -1 164 ASP   B OD2  1 
ATOM   2579  H  H    . ASP   A 1 165 ? 16.521  7.877   38.607  1.00 33.97  ?  164 ASP   B H    1 
ATOM   2580  H  HA   . ASP   A 1 165 ? 15.995  6.845   41.044  1.00 38.99  ?  164 ASP   B HA   1 
ATOM   2581  H  HB2  . ASP   A 1 165 ? 17.107  8.940   40.993  1.00 35.64  ?  164 ASP   B HB2  1 
ATOM   2582  H  HB3  . ASP   A 1 165 ? 15.845  9.564   40.256  1.00 35.64  ?  164 ASP   B HB3  1 
ATOM   2583  N  N    . VAL   A 1 166 ? 13.582  6.566   40.944  1.00 27.69  ?  165 VAL   B N    1 
ATOM   2584  C  CA   . VAL   A 1 166 ? 12.142  6.344   40.756  1.00 32.31  ?  165 VAL   B CA   1 
ATOM   2585  C  C    . VAL   A 1 166 ? 11.364  7.649   40.880  1.00 29.12  ?  165 VAL   B C    1 
ATOM   2586  O  O    . VAL   A 1 166 ? 10.548  7.983   40.013  1.00 25.20  ?  165 VAL   B O    1 
ATOM   2587  C  CB   . VAL   A 1 166 ? 11.597  5.295   41.737  1.00 24.29  ?  165 VAL   B CB   1 
ATOM   2588  C  CG1  . VAL   A 1 166 ? 10.070  5.260   41.593  1.00 25.44  ?  165 VAL   B CG1  1 
ATOM   2589  C  CG2  . VAL   A 1 166 ? 12.187  3.917   41.486  1.00 28.52  ?  165 VAL   B CG2  1 
ATOM   2590  H  H    . VAL   A 1 166 ? 13.934  6.118   41.589  1.00 33.23  ?  165 VAL   B H    1 
ATOM   2591  H  HA   . VAL   A 1 166 ? 12.028  6.003   39.855  1.00 38.78  ?  165 VAL   B HA   1 
ATOM   2592  H  HB   . VAL   A 1 166 ? 11.847  5.537   42.643  1.00 29.15  ?  165 VAL   B HB   1 
ATOM   2593  H  HG11 . VAL   A 1 166 ? 9.746   4.388   41.868  1.00 30.53  ?  165 VAL   B HG11 1 
ATOM   2594  H  HG12 . VAL   A 1 166 ? 9.684   5.950   42.155  1.00 30.53  ?  165 VAL   B HG12 1 
ATOM   2595  H  HG13 . VAL   A 1 166 ? 9.837   5.421   40.665  1.00 30.53  ?  165 VAL   B HG13 1 
ATOM   2596  H  HG21 . VAL   A 1 166 ? 11.827  3.295   42.137  1.00 34.22  ?  165 VAL   B HG21 1 
ATOM   2597  H  HG22 . VAL   A 1 166 ? 11.951  3.631   40.589  1.00 34.22  ?  165 VAL   B HG22 1 
ATOM   2598  H  HG23 . VAL   A 1 166 ? 13.152  3.966   41.574  1.00 34.22  ?  165 VAL   B HG23 1 
ATOM   2599  N  N    . ARG   A 1 167 ? 11.639  8.418   41.933  1.00 23.71  ?  166 ARG   B N    1 
ATOM   2600  C  CA   . ARG   A 1 167 ? 10.948  9.677   42.153  1.00 28.38  ?  166 ARG   B CA   1 
ATOM   2601  C  C    . ARG   A 1 167 ? 11.128  10.627  40.974  1.00 31.80  ?  166 ARG   B C    1 
ATOM   2602  O  O    . ARG   A 1 167 ? 10.145  11.216  40.504  1.00 41.76  ?  166 ARG   B O    1 
ATOM   2603  C  CB   . ARG   A 1 167 ? 11.419  10.310  43.462  1.00 28.08  ?  166 ARG   B CB   1 
ATOM   2604  C  CG   . ARG   A 1 167 ? 10.759  11.667  43.815  1.00 28.41  ?  166 ARG   B CG   1 
ATOM   2605  C  CD   . ARG   A 1 167 ? 11.330  12.189  45.132  1.00 34.39  ?  166 ARG   B CD   1 
ATOM   2606  N  NE   . ARG   A 1 167 ? 12.722  12.575  44.956  1.00 37.92  ?  166 ARG   B NE   1 
ATOM   2607  C  CZ   . ARG   A 1 167 ? 13.068  13.795  44.587  1.00 41.95  ?  166 ARG   B CZ   1 
ATOM   2608  N  NH1  . ARG   A 1 167 ? 12.150  14.749  44.486  1.00 36.41  ?  166 ARG   B NH1  1 
ATOM   2609  N  NH2  . ARG   A 1 167 ? 14.361  14.066  44.327  1.00 46.81  ?  166 ARG   B NH2  1 
ATOM   2610  H  H    . ARG   A 1 167 ? 12.224  8.230   42.534  1.00 28.45  ?  166 ARG   B H    1 
ATOM   2611  H  HA   . ARG   A 1 167 ? 9.998   9.505   42.238  1.00 34.06  ?  166 ARG   B HA   1 
ATOM   2612  H  HB2  . ARG   A 1 167 ? 11.224  9.696   44.187  1.00 33.70  ?  166 ARG   B HB2  1 
ATOM   2613  H  HB3  . ARG   A 1 167 ? 12.376  10.460  43.403  1.00 33.70  ?  166 ARG   B HB3  1 
ATOM   2614  H  HG2  . ARG   A 1 167 ? 10.944  12.313  43.116  1.00 34.09  ?  166 ARG   B HG2  1 
ATOM   2615  H  HG3  . ARG   A 1 167 ? 9.801   11.550  43.913  1.00 34.09  ?  166 ARG   B HG3  1 
ATOM   2616  H  HD2  . ARG   A 1 167 ? 10.825  12.965  45.421  1.00 41.26  ?  166 ARG   B HD2  1 
ATOM   2617  H  HD3  . ARG   A 1 167 ? 11.283  11.493  45.807  1.00 41.26  ?  166 ARG   B HD3  1 
ATOM   2618  H  HE   . ARG   A 1 167 ? 13.337  11.992  45.097  1.00 45.50  ?  166 ARG   B HE   1 
ATOM   2619  H  HH11 . ARG   A 1 167 ? 11.326  14.573  44.662  1.00 43.69  ?  166 ARG   B HH11 1 
ATOM   2620  H  HH12 . ARG   A 1 167 ? 12.379  15.542  44.246  1.00 43.69  ?  166 ARG   B HH12 1 
ATOM   2621  H  HH21 . ARG   A 1 167 ? 14.954  13.447  44.402  1.00 56.17  ?  166 ARG   B HH21 1 
ATOM   2622  H  HH22 . ARG   A 1 167 ? 14.595  14.858  44.086  1.00 56.17  ?  166 ARG   B HH22 1 
ATOM   2623  N  N    . GLU   A 1 168 ? 12.336  10.754  40.460  1.00 31.79  ?  167 GLU   B N    1 
ATOM   2624  C  CA   . GLU   A 1 168 ? 12.618  11.637  39.339  1.00 33.25  ?  167 GLU   B CA   1 
ATOM   2625  C  C    . GLU   A 1 168 ? 11.953  11.139  38.059  1.00 28.83  ?  167 GLU   B C    1 
ATOM   2626  O  O    . GLU   A 1 168 ? 11.420  11.893  37.323  1.00 28.68  ?  167 GLU   B O    1 
ATOM   2627  C  CB   . GLU   A 1 168 ? 14.124  11.866  39.178  1.00 32.70  ?  167 GLU   B CB   1 
ATOM   2628  C  CG   . GLU   A 1 168 ? 14.726  12.720  40.286  1.00 40.08  ?  167 GLU   B CG   1 
ATOM   2629  C  CD   . GLU   A 1 168 ? 16.157  13.198  40.039  1.00 51.87  ?  167 GLU   B CD   1 
ATOM   2630  O  OE1  . GLU   A 1 168 ? 17.059  12.810  40.750  1.00 48.90  ?  167 GLU   B OE1  1 
ATOM   2631  O  OE2  . GLU   A 1 168 ? 16.386  14.034  39.181  1.00 47.59  -1 167 GLU   B OE2  1 
ATOM   2632  H  H    . GLU   A 1 168 ? 13.027  10.331  40.749  1.00 38.14  ?  167 GLU   B H    1 
ATOM   2633  H  HA   . GLU   A 1 168 ? 12.221  12.510  39.540  1.00 39.90  ?  167 GLU   B HA   1 
ATOM   2634  H  HB2  . GLU   A 1 168 ? 14.576  11.008  39.186  1.00 39.24  ?  167 GLU   B HB2  1 
ATOM   2635  H  HB3  . GLU   A 1 168 ? 14.285  12.317  38.335  1.00 39.24  ?  167 GLU   B HB3  1 
ATOM   2636  H  HG2  . GLU   A 1 168 ? 14.171  13.508  40.402  1.00 48.10  ?  167 GLU   B HG2  1 
ATOM   2637  H  HG3  . GLU   A 1 168 ? 14.728  12.202  41.106  1.00 48.10  ?  167 GLU   B HG3  1 
ATOM   2638  N  N    . THR   A 1 169 ? 11.982  9.855   37.826  1.00 29.13  ?  168 THR   B N    1 
ATOM   2639  C  CA   . THR   A 1 169 ? 11.278  9.279   36.682  1.00 29.92  ?  168 THR   B CA   1 
ATOM   2640  C  C    . THR   A 1 169 ? 9.774   9.546   36.737  1.00 34.30  ?  168 THR   B C    1 
ATOM   2641  O  O    . THR   A 1 169 ? 9.147   9.857   35.715  1.00 32.84  ?  168 THR   B O    1 
ATOM   2642  C  CB   . THR   A 1 169 ? 11.523  7.768   36.645  1.00 31.45  ?  168 THR   B CB   1 
ATOM   2643  O  OG1  . THR   A 1 169 ? 12.918  7.520   36.698  1.00 32.94  ?  168 THR   B OG1  1 
ATOM   2644  C  CG2  . THR   A 1 169 ? 10.986  7.109   35.410  1.00 37.71  ?  168 THR   B CG2  1 
ATOM   2645  H  H    . THR   A 1 169 ? 12.396  9.285   38.319  1.00 34.96  ?  168 THR   B H    1 
ATOM   2646  H  HA   . THR   A 1 169 ? 11.627  9.688   35.874  1.00 35.91  ?  168 THR   B HA   1 
ATOM   2647  H  HB   . THR   A 1 169 ? 11.060  7.381   37.405  1.00 37.74  ?  168 THR   B HB   1 
ATOM   2648  H  HG1  . THR   A 1 169 ? 13.068  6.701   36.595  1.00 39.53  ?  168 THR   B HG1  1 
ATOM   2649  H  HG21 . THR   A 1 169 ? 11.481  6.296   35.226  1.00 45.26  ?  168 THR   B HG21 1 
ATOM   2650  H  HG22 . THR   A 1 169 ? 10.050  6.887   35.533  1.00 45.26  ?  168 THR   B HG22 1 
ATOM   2651  H  HG23 . THR   A 1 169 ? 11.071  7.708   34.652  1.00 45.26  ?  168 THR   B HG23 1 
ATOM   2652  N  N    . MET   A 1 170 ? 9.156   9.356   37.898  1.00 32.40  ?  169 MET   B N    1 
ATOM   2653  C  CA   . MET   A 1 170 ? 7.717   9.606   37.987  1.00 34.02  ?  169 MET   B CA   1 
ATOM   2654  C  C    . MET   A 1 170 ? 7.431   11.082  37.803  1.00 35.61  ?  169 MET   B C    1 
ATOM   2655  O  O    . MET   A 1 170 ? 6.426   11.453  37.184  1.00 30.80  ?  169 MET   B O    1 
ATOM   2656  C  CB   . MET   A 1 170 ? 7.176   9.095   39.313  1.00 33.39  ?  169 MET   B CB   1 
ATOM   2657  C  CG   . MET   A 1 170 ? 7.499   7.653   39.499  1.00 41.78  ?  169 MET   B CG   1 
ATOM   2658  S  SD   . MET   A 1 170 ? 6.356   6.464   38.843  1.00 42.55  ?  169 MET   B SD   1 
ATOM   2659  C  CE   . MET   A 1 170 ? 4.919   7.108   39.748  1.00 56.84  ?  169 MET   B CE   1 
ATOM   2660  H  H    . MET   A 1 170 ? 9.531   9.093   38.626  1.00 38.88  ?  169 MET   B H    1 
ATOM   2661  H  HA   . MET   A 1 170 ? 7.254   9.108   37.294  1.00 40.82  ?  169 MET   B HA   1 
ATOM   2662  H  HB2  . MET   A 1 170 ? 7.577   9.597   40.040  1.00 40.07  ?  169 MET   B HB2  1 
ATOM   2663  H  HB3  . MET   A 1 170 ? 6.212   9.200   39.331  1.00 40.07  ?  169 MET   B HB3  1 
ATOM   2664  H  HG2  . MET   A 1 170 ? 8.354   7.483   39.073  1.00 50.14  ?  169 MET   B HG2  1 
ATOM   2665  H  HG3  . MET   A 1 170 ? 7.564   7.483   40.451  1.00 50.14  ?  169 MET   B HG3  1 
ATOM   2666  H  HE1  . MET   A 1 170 ? 4.145   6.561   39.541  1.00 68.20  ?  169 MET   B HE1  1 
ATOM   2667  H  HE2  . MET   A 1 170 ? 5.104   7.073   40.699  1.00 68.20  ?  169 MET   B HE2  1 
ATOM   2668  H  HE3  . MET   A 1 170 ? 4.759   8.025   39.475  1.00 68.20  ?  169 MET   B HE3  1 
ATOM   2669  N  N    . SER   A 1 171 ? 8.363   11.930  38.238  1.00 31.38  ?  170 SER   B N    1 
ATOM   2670  C  CA   . SER   A 1 171 ? 8.181   13.361  38.055  1.00 38.20  ?  170 SER   B CA   1 
ATOM   2671  C  C    . SER   A 1 171 ? 8.222   13.736  36.581  1.00 37.64  ?  170 SER   B C    1 
ATOM   2672  O  O    . SER   A 1 171 ? 7.457   14.601  36.137  1.00 38.57  ?  170 SER   B O    1 
ATOM   2673  C  CB   . SER   A 1 171 ? 9.236   14.119  38.859  1.00 31.45  ?  170 SER   B CB   1 
ATOM   2674  O  OG   . SER   A 1 171 ? 8.976   15.508  38.772  1.00 47.22  ?  170 SER   B OG   1 
ATOM   2675  H  H    . SER   A 1 171 ? 9.093   11.704  38.634  1.00 37.66  ?  170 SER   B H    1 
ATOM   2676  H  HA   . SER   A 1 171 ? 7.310   13.624  38.393  1.00 45.84  ?  170 SER   B HA   1 
ATOM   2677  H  HB2  . SER   A 1 171 ? 9.195   13.840  39.787  1.00 37.75  ?  170 SER   B HB2  1 
ATOM   2678  H  HB3  . SER   A 1 171 ? 10.115  13.931  38.495  1.00 37.75  ?  170 SER   B HB3  1 
ATOM   2679  H  HG   . SER   A 1 171 ? 9.088   15.772  37.983  1.00 56.67  ?  170 SER   B HG   1 
ATOM   2680  N  N    . TYR   A 1 172 ? 9.100   13.098  35.805  1.00 34.35  ?  171 TYR   B N    1 
ATOM   2681  C  CA   . TYR   A 1 172 ? 9.144   13.406  34.379  1.00 44.16  ?  171 TYR   B CA   1 
ATOM   2682  C  C    . TYR   A 1 172 ? 7.851   12.968  33.730  1.00 36.87  ?  171 TYR   B C    1 
ATOM   2683  O  O    . TYR   A 1 172 ? 7.319   13.651  32.858  1.00 40.83  ?  171 TYR   B O    1 
ATOM   2684  C  CB   . TYR   A 1 172 ? 10.296  12.698  33.651  1.00 36.83  ?  171 TYR   B CB   1 
ATOM   2685  C  CG   . TYR   A 1 172 ? 11.616  13.420  33.610  1.00 53.32  ?  171 TYR   B CG   1 
ATOM   2686  C  CD1  . TYR   A 1 172 ? 11.748  14.679  33.021  1.00 57.44  ?  171 TYR   B CD1  1 
ATOM   2687  C  CD2  . TYR   A 1 172 ? 12.778  12.807  34.142  1.00 61.77  ?  171 TYR   B CD2  1 
ATOM   2688  C  CE1  . TYR   A 1 172 ? 13.008  15.324  32.998  1.00 73.68  ?  171 TYR   B CE1  1 
ATOM   2689  C  CE2  . TYR   A 1 172 ? 14.036  13.436  34.101  1.00 62.06  ?  171 TYR   B CE2  1 
ATOM   2690  C  CZ   . TYR   A 1 172 ? 14.136  14.685  33.537  1.00 68.02  ?  171 TYR   B CZ   1 
ATOM   2691  O  OH   . TYR   A 1 172 ? 15.368  15.293  33.510  1.00 72.72  ?  171 TYR   B OH   1 
ATOM   2692  H  H    . TYR   A 1 172 ? 9.661   12.504  36.071  1.00 41.22  ?  171 TYR   B H    1 
ATOM   2693  H  HA   . TYR   A 1 172 ? 9.289   14.361  34.296  1.00 52.99  ?  171 TYR   B HA   1 
ATOM   2694  H  HB2  . TYR   A 1 172 ? 10.451  11.847  34.091  1.00 44.19  ?  171 TYR   B HB2  1 
ATOM   2695  H  HB3  . TYR   A 1 172 ? 10.024  12.550  32.732  1.00 44.19  ?  171 TYR   B HB3  1 
ATOM   2696  H  HD1  . TYR   A 1 172 ? 11.007  15.094  32.643  1.00 68.93  ?  171 TYR   B HD1  1 
ATOM   2697  H  HD2  . TYR   A 1 172 ? 12.707  11.964  34.530  1.00 74.13  ?  171 TYR   B HD2  1 
ATOM   2698  H  HE1  . TYR   A 1 172 ? 13.089  16.173  32.625  1.00 88.42  ?  171 TYR   B HE1  1 
ATOM   2699  H  HE2  . TYR   A 1 172 ? 14.787  13.014  34.450  1.00 74.47  ?  171 TYR   B HE2  1 
ATOM   2700  H  HH   . TYR   A 1 172 ? 15.935  14.812  33.901  1.00 87.26  ?  171 TYR   B HH   1 
ATOM   2701  N  N    . LEU   A 1 173 ? 7.347   11.807  34.139  1.00 35.28  ?  172 LEU   B N    1 
ATOM   2702  C  CA   . LEU   A 1 173 ? 6.141   11.258  33.531  1.00 34.91  ?  172 LEU   B CA   1 
ATOM   2703  C  C    . LEU   A 1 173 ? 4.903   12.036  33.964  1.00 37.77  ?  172 LEU   B C    1 
ATOM   2704  O  O    . LEU   A 1 173 ? 4.036   12.347  33.144  1.00 37.03  ?  172 LEU   B O    1 
ATOM   2705  C  CB   . LEU   A 1 173 ? 5.997   9.797   33.913  1.00 37.62  ?  172 LEU   B CB   1 
ATOM   2706  C  CG   . LEU   A 1 173 ? 7.034   8.923   33.232  1.00 37.13  ?  172 LEU   B CG   1 
ATOM   2707  C  CD1  . LEU   A 1 173 ? 6.420   7.522   33.161  1.00 42.39  ?  172 LEU   B CD1  1 
ATOM   2708  C  CD2  . LEU   A 1 173 ? 7.453   9.397   31.869  1.00 49.81  ?  172 LEU   B CD2  1 
ATOM   2709  H  H    . LEU   A 1 173 ? 7.682   11.320  34.763  1.00 42.33  ?  172 LEU   B H    1 
ATOM   2710  H  HA   . LEU   A 1 173 ? 6.220   11.322  32.566  1.00 41.90  ?  172 LEU   B HA   1 
ATOM   2711  H  HB2  . LEU   A 1 173 ? 6.108   9.708   34.872  1.00 45.14  ?  172 LEU   B HB2  1 
ATOM   2712  H  HB3  . LEU   A 1 173 ? 5.117   9.486   33.650  1.00 45.14  ?  172 LEU   B HB3  1 
ATOM   2713  H  HG   . LEU   A 1 173 ? 7.860   8.940   33.741  1.00 44.55  ?  172 LEU   B HG   1 
ATOM   2714  H  HD11 . LEU   A 1 173 ? 7.037   6.930   32.703  1.00 50.87  ?  172 LEU   B HD11 1 
ATOM   2715  H  HD12 . LEU   A 1 173 ? 6.262   7.201   34.063  1.00 50.87  ?  172 LEU   B HD12 1 
ATOM   2716  H  HD13 . LEU   A 1 173 ? 5.583   7.569   32.674  1.00 50.87  ?  172 LEU   B HD13 1 
ATOM   2717  H  HD21 . LEU   A 1 173 ? 8.052   8.743   31.477  1.00 59.77  ?  172 LEU   B HD21 1 
ATOM   2718  H  HD22 . LEU   A 1 173 ? 6.664   9.498   31.313  1.00 59.77  ?  172 LEU   B HD22 1 
ATOM   2719  H  HD23 . LEU   A 1 173 ? 7.906   10.250  31.957  1.00 59.77  ?  172 LEU   B HD23 1 
ATOM   2720  N  N    . PHE   A 1 174 ? 4.761   12.317  35.260  1.00 33.63  ?  173 PHE   B N    1 
ATOM   2721  C  CA   . PHE   A 1 174 ? 3.623   13.142  35.651  1.00 35.91  ?  173 PHE   B CA   1 
ATOM   2722  C  C    . PHE   A 1 174 ? 3.558   14.410  34.806  1.00 38.83  ?  173 PHE   B C    1 
ATOM   2723  O  O    . PHE   A 1 174 ? 2.462   14.908  34.506  1.00 36.05  ?  173 PHE   B O    1 
ATOM   2724  C  CB   . PHE   A 1 174 ? 3.672   13.522  37.128  1.00 39.93  ?  173 PHE   B CB   1 
ATOM   2725  C  CG   . PHE   A 1 174 ? 3.555   12.345  38.049  1.00 34.72  ?  173 PHE   B CG   1 
ATOM   2726  C  CD1  . PHE   A 1 174 ? 3.018   11.139  37.603  1.00 37.01  ?  173 PHE   B CD1  1 
ATOM   2727  C  CD2  . PHE   A 1 174 ? 3.982   12.429  39.341  1.00 33.10  ?  173 PHE   B CD2  1 
ATOM   2728  C  CE1  . PHE   A 1 174 ? 2.906   10.061  38.459  1.00 37.94  ?  173 PHE   B CE1  1 
ATOM   2729  C  CE2  . PHE   A 1 174 ? 3.891   11.330  40.197  1.00 38.02  ?  173 PHE   B CE2  1 
ATOM   2730  C  CZ   . PHE   A 1 174 ? 3.359   10.172  39.774  1.00 32.83  ?  173 PHE   B CZ   1 
ATOM   2731  H  H    . PHE   A 1 174 ? 5.280   12.057  35.894  1.00 40.35  ?  173 PHE   B H    1 
ATOM   2732  H  HA   . PHE   A 1 174 ? 2.818   12.616  35.520  1.00 43.09  ?  173 PHE   B HA   1 
ATOM   2733  H  HB2  . PHE   A 1 174 ? 4.519   13.960  37.310  1.00 47.91  ?  173 PHE   B HB2  1 
ATOM   2734  H  HB3  . PHE   A 1 174 ? 2.938   14.126  37.321  1.00 47.91  ?  173 PHE   B HB3  1 
ATOM   2735  H  HD1  . PHE   A 1 174 ? 2.732   11.060  36.722  1.00 44.41  ?  173 PHE   B HD1  1 
ATOM   2736  H  HD2  . PHE   A 1 174 ? 4.339   13.228  39.655  1.00 39.72  ?  173 PHE   B HD2  1 
ATOM   2737  H  HE1  . PHE   A 1 174 ? 2.531   9.264   38.159  1.00 45.53  ?  173 PHE   B HE1  1 
ATOM   2738  H  HE2  . PHE   A 1 174 ? 4.203   11.401  41.071  1.00 45.63  ?  173 PHE   B HE2  1 
ATOM   2739  H  HZ   . PHE   A 1 174 ? 3.292   9.448   40.354  1.00 39.40  ?  173 PHE   B HZ   1 
ATOM   2740  N  N    . GLN   A 1 175 ? 4.724   14.929  34.397  1.00 38.04  ?  174 GLN   B N    1 
ATOM   2741  C  CA   . GLN   A 1 175 ? 4.796   16.133  33.581  1.00 43.93  ?  174 GLN   B CA   1 
ATOM   2742  C  C    . GLN   A 1 175 ? 4.203   15.928  32.194  1.00 42.52  ?  174 GLN   B C    1 
ATOM   2743  O  O    . GLN   A 1 175 ? 3.988   16.909  31.478  1.00 45.79  ?  174 GLN   B O    1 
ATOM   2744  C  CB   . GLN   A 1 175 ? 6.250   16.594  33.471  1.00 38.83  ?  174 GLN   B CB   1 
ATOM   2745  C  CG   . GLN   A 1 175 ? 6.665   17.619  34.546  1.00 43.37  ?  174 GLN   B CG   1 
ATOM   2746  C  CD   . GLN   A 1 175 ? 6.206   19.036  34.171  1.00 68.53  ?  174 GLN   B CD   1 
ATOM   2747  O  OE1  . GLN   A 1 175 ? 5.301   19.597  34.803  1.00 66.85  ?  174 GLN   B OE1  1 
ATOM   2748  N  NE2  . GLN   A 1 175 ? 6.835   19.621  33.137  1.00 74.88  ?  174 GLN   B NE2  1 
ATOM   2749  H  H    . GLN   A 1 175 ? 5.493   14.593  34.585  1.00 45.65  ?  174 GLN   B H    1 
ATOM   2750  H  HA   . GLN   A 1 175 ? 4.295   16.843  34.013  1.00 52.72  ?  174 GLN   B HA   1 
ATOM   2751  H  HB2  . GLN   A 1 175 ? 6.829   15.821  33.560  1.00 46.60  ?  174 GLN   B HB2  1 
ATOM   2752  H  HB3  . GLN   A 1 175 ? 6.381   17.007  32.603  1.00 46.60  ?  174 GLN   B HB3  1 
ATOM   2753  H  HG2  . GLN   A 1 175 ? 6.257   17.379  35.393  1.00 52.04  ?  174 GLN   B HG2  1 
ATOM   2754  H  HG3  . GLN   A 1 175 ? 7.631   17.622  34.632  1.00 52.04  ?  174 GLN   B HG3  1 
ATOM   2755  H  HE21 . GLN   A 1 175 ? 7.461   19.202  32.721  1.00 89.85  ?  174 GLN   B HE21 1 
ATOM   2756  H  HE22 . GLN   A 1 175 ? 6.611   20.415  32.891  1.00 89.85  ?  174 GLN   B HE22 1 
ATOM   2757  N  N    . HIS   A 1 176 ? 3.938   14.688  31.803  1.00 37.72  ?  175 HIS   B N    1 
ATOM   2758  C  CA   . HIS   A 1 176 ? 3.231   14.378  30.575  1.00 40.97  ?  175 HIS   B CA   1 
ATOM   2759  C  C    . HIS   A 1 176 ? 1.866   13.775  30.849  1.00 38.95  ?  175 HIS   B C    1 
ATOM   2760  O  O    . HIS   A 1 176 ? 1.241   13.218  29.942  1.00 42.33  ?  175 HIS   B O    1 
ATOM   2761  C  CB   . HIS   A 1 176 ? 4.055   13.405  29.741  1.00 38.98  ?  175 HIS   B CB   1 
ATOM   2762  C  CG   . HIS   A 1 176 ? 5.166   14.056  28.978  1.00 45.78  ?  175 HIS   B CG   1 
ATOM   2763  N  ND1  . HIS   A 1 176 ? 4.942   14.829  27.855  1.00 48.42  ?  175 HIS   B ND1  1 
ATOM   2764  C  CD2  . HIS   A 1 176 ? 6.501   14.094  29.198  1.00 39.97  ?  175 HIS   B CD2  1 
ATOM   2765  C  CE1  . HIS   A 1 176 ? 6.090   15.290  27.394  1.00 41.16  ?  175 HIS   B CE1  1 
ATOM   2766  N  NE2  . HIS   A 1 176 ? 7.052   14.859  28.191  1.00 44.94  ?  175 HIS   B NE2  1 
ATOM   2767  H  H    . HIS   A 1 176 ? 4.166   13.989  32.249  1.00 45.26  ?  175 HIS   B H    1 
ATOM   2768  H  HA   . HIS   A 1 176 ? 3.109   15.194  30.065  1.00 49.16  ?  175 HIS   B HA   1 
ATOM   2769  H  HB2  . HIS   A 1 176 ? 4.449   12.744  30.331  1.00 46.78  ?  175 HIS   B HB2  1 
ATOM   2770  H  HB3  . HIS   A 1 176 ? 3.471   12.972  29.100  1.00 46.78  ?  175 HIS   B HB3  1 
ATOM   2771  H  HD2  . HIS   A 1 176 ? 6.959   13.683  29.895  1.00 47.96  ?  175 HIS   B HD2  1 
ATOM   2772  H  HE1  . HIS   A 1 176 ? 6.202   15.825  26.642  1.00 49.40  ?  175 HIS   B HE1  1 
ATOM   2773  H  HE2  . HIS   A 1 176 ? 7.890   15.028  28.097  1.00 53.93  ?  175 HIS   B HE2  1 
ATOM   2774  N  N    . ALA   A 1 177 ? 1.389   13.853  32.073  1.00 30.91  ?  176 ALA   B N    1 
ATOM   2775  C  CA   . ALA   A 1 177 ? 0.077   13.321  32.396  1.00 40.41  ?  176 ALA   B CA   1 
ATOM   2776  C  C    . ALA   A 1 177 ? -0.870  14.475  32.643  1.00 41.61  ?  176 ALA   B C    1 
ATOM   2777  O  O    . ALA   A 1 177 ? -0.440  15.597  32.901  1.00 46.20  ?  176 ALA   B O    1 
ATOM   2778  C  CB   . ALA   A 1 177 ? 0.134   12.413  33.615  1.00 35.31  ?  176 ALA   B CB   1 
ATOM   2779  H  H    . ALA   A 1 177 ? 1.805   14.208  32.736  1.00 37.10  ?  176 ALA   B H    1 
ATOM   2780  H  HA   . ALA   A 1 177 ? -0.259  12.789  31.657  1.00 48.50  ?  176 ALA   B HA   1 
ATOM   2781  H  HB1  . ALA   A 1 177 ? -0.769  12.157  33.861  1.00 42.37  ?  176 ALA   B HB1  1 
ATOM   2782  H  HB2  . ALA   A 1 177 ? 0.653   11.623  33.397  1.00 42.37  ?  176 ALA   B HB2  1 
ATOM   2783  H  HB3  . ALA   A 1 177 ? 0.552   12.893  34.347  1.00 42.37  ?  176 ALA   B HB3  1 
ATOM   2784  N  N    . ASN   A 1 178 ? -2.162  14.188  32.576  1.00 44.66  ?  177 ASN   B N    1 
ATOM   2785  C  CA   . ASN   A 1 178 ? -3.172  15.218  32.776  1.00 44.19  ?  177 ASN   B CA   1 
ATOM   2786  C  C    . ASN   A 1 178 ? -3.462  15.296  34.268  1.00 45.18  ?  177 ASN   B C    1 
ATOM   2787  O  O    . ASN   A 1 178 ? -4.278  14.531  34.800  1.00 43.13  ?  177 ASN   B O    1 
ATOM   2788  C  CB   . ASN   A 1 178 ? -4.437  14.922  31.979  1.00 46.69  ?  177 ASN   B CB   1 
ATOM   2789  C  CG   . ASN   A 1 178 ? -5.519  16.004  32.168  1.00 51.37  ?  177 ASN   B CG   1 
ATOM   2790  O  OD1  . ASN   A 1 178 ? -5.495  16.790  33.123  1.00 50.43  ?  177 ASN   B OD1  1 
ATOM   2791  N  ND2  . ASN   A 1 178 ? -6.458  16.043  31.240  1.00 52.62  ?  177 ASN   B ND2  1 
ATOM   2792  H  H    . ASN   A 1 178 ? -2.479  13.405  32.416  1.00 53.59  ?  177 ASN   B H    1 
ATOM   2793  H  HA   . ASN   A 1 178 ? -2.823  16.070  32.472  1.00 53.02  ?  177 ASN   B HA   1 
ATOM   2794  H  HB2  . ASN   A 1 178 ? -4.215  14.880  31.036  1.00 56.03  ?  177 ASN   B HB2  1 
ATOM   2795  H  HB3  . ASN   A 1 178 ? -4.805  14.074  32.272  1.00 56.03  ?  177 ASN   B HB3  1 
ATOM   2796  H  HD21 . ASN   A 1 178 ? -6.438  15.487  30.585  1.00 63.15  ?  177 ASN   B HD21 1 
ATOM   2797  H  HD22 . ASN   A 1 178 ? -7.089  16.625  31.291  1.00 63.15  ?  177 ASN   B HD22 1 
ATOM   2798  N  N    . LEU   A 1 179 ? -2.818  16.251  34.937  1.00 45.13  ?  178 LEU   B N    1 
ATOM   2799  C  CA   . LEU   A 1 179 ? -3.041  16.514  36.356  1.00 40.34  ?  178 LEU   B CA   1 
ATOM   2800  C  C    . LEU   A 1 179 ? -3.612  17.914  36.604  1.00 45.51  ?  178 LEU   B C    1 
ATOM   2801  O  O    . LEU   A 1 179 ? -3.493  18.448  37.715  1.00 45.04  ?  178 LEU   B O    1 
ATOM   2802  C  CB   . LEU   A 1 179 ? -1.726  16.319  37.112  1.00 46.38  ?  178 LEU   B CB   1 
ATOM   2803  C  CG   . LEU   A 1 179 ? -1.155  14.903  36.995  1.00 44.51  ?  178 LEU   B CG   1 
ATOM   2804  C  CD1  . LEU   A 1 179 ? 0.232   14.849  37.586  1.00 47.09  ?  178 LEU   B CD1  1 
ATOM   2805  C  CD2  . LEU   A 1 179 ? -2.058  13.892  37.722  1.00 45.70  ?  178 LEU   B CD2  1 
ATOM   2806  H  H    . LEU   A 1 179 ? -2.234  16.772  34.582  1.00 54.16  ?  178 LEU   B H    1 
ATOM   2807  H  HA   . LEU   A 1 179 ? -3.693  15.885  36.702  1.00 48.41  ?  178 LEU   B HA   1 
ATOM   2808  H  HB2  . LEU   A 1 179 ? -1.067  16.936  36.757  1.00 55.65  ?  178 LEU   B HB2  1 
ATOM   2809  H  HB3  . LEU   A 1 179 ? -1.877  16.501  38.053  1.00 55.65  ?  178 LEU   B HB3  1 
ATOM   2810  H  HG   . LEU   A 1 179 ? -1.110  14.663  36.056  1.00 53.41  ?  178 LEU   B HG   1 
ATOM   2811  H  HD11 . LEU   A 1 179 ? 0.574   13.945  37.508  1.00 56.51  ?  178 LEU   B HD11 1 
ATOM   2812  H  HD12 . LEU   A 1 179 ? 0.806   15.463  37.102  1.00 56.51  ?  178 LEU   B HD12 1 
ATOM   2813  H  HD13 . LEU   A 1 179 ? 0.187   15.106  38.521  1.00 56.51  ?  178 LEU   B HD13 1 
ATOM   2814  H  HD21 . LEU   A 1 179 ? -1.545  13.453  38.418  1.00 54.84  ?  178 LEU   B HD21 1 
ATOM   2815  H  HD22 . LEU   A 1 179 ? -2.810  14.364  38.113  1.00 54.84  ?  178 LEU   B HD22 1 
ATOM   2816  H  HD23 . LEU   A 1 179 ? -2.377  13.236  37.082  1.00 54.84  ?  178 LEU   B HD23 1 
ATOM   2817  N  N    . ASP   A 1 180 ? -4.274  18.494  35.601  1.00 59.90  ?  179 ASP   B N    1 
ATOM   2818  C  CA   . ASP   A 1 180 ? -4.765  19.867  35.701  1.00 67.64  ?  179 ASP   B CA   1 
ATOM   2819  C  C    . ASP   A 1 180 ? -5.664  20.049  36.912  1.00 59.04  ?  179 ASP   B C    1 
ATOM   2820  O  O    . ASP   A 1 180 ? -5.527  21.013  37.674  1.00 58.23  ?  179 ASP   B O    1 
ATOM   2821  C  CB   . ASP   A 1 180 ? -5.527  20.238  34.423  1.00 68.47  ?  179 ASP   B CB   1 
ATOM   2822  C  CG   . ASP   A 1 180 ? -4.608  20.521  33.252  1.00 81.92  ?  179 ASP   B CG   1 
ATOM   2823  O  OD1  . ASP   A 1 180 ? -4.935  20.046  32.146  1.00 79.03  ?  179 ASP   B OD1  1 
ATOM   2824  O  OD2  . ASP   A 1 180 ? -3.585  21.236  33.429  1.00 93.42  -1 179 ASP   B OD2  1 
ATOM   2825  H  H    . ASP   A 1 180 ? -4.452  18.113  34.851  1.00 71.88  ?  179 ASP   B H    1 
ATOM   2826  H  HA   . ASP   A 1 180 ? -4.003  20.460  35.796  1.00 81.17  ?  179 ASP   B HA   1 
ATOM   2827  H  HB2  . ASP   A 1 180 ? -6.108  19.501  34.177  1.00 82.16  ?  179 ASP   B HB2  1 
ATOM   2828  H  HB3  . ASP   A 1 180 ? -6.055  21.035  34.590  1.00 82.16  ?  179 ASP   B HB3  1 
ATOM   2829  N  N    . SER   A 1 181 ? -6.600  19.145  37.095  1.00 46.30  ?  180 SER   B N    1 
ATOM   2830  C  CA   . SER   A 1 181 ? -7.571  19.278  38.168  1.00 61.34  ?  180 SER   B CA   1 
ATOM   2831  C  C    . SER   A 1 181 ? -7.020  18.872  39.542  1.00 60.12  ?  180 SER   B C    1 
ATOM   2832  O  O    . SER   A 1 181 ? -7.816  18.664  40.470  1.00 62.61  ?  180 SER   B O    1 
ATOM   2833  C  CB   . SER   A 1 181 ? -8.808  18.445  37.850  1.00 60.72  ?  180 SER   B CB   1 
ATOM   2834  O  OG   . SER   A 1 181 ? -8.499  17.077  38.002  1.00 61.01  ?  180 SER   B OG   1 
ATOM   2835  H  H    . SER   A 1 181 ? -6.698  18.441  36.610  1.00 55.56  ?  180 SER   B H    1 
ATOM   2836  H  HA   . SER   A 1 181 ? -7.831  20.211  38.221  1.00 73.61  ?  180 SER   B HA   1 
ATOM   2837  H  HB2  . SER   A 1 181 ? -9.523  18.684  38.461  1.00 72.86  ?  180 SER   B HB2  1 
ATOM   2838  H  HB3  . SER   A 1 181 ? -9.084  18.614  36.935  1.00 72.86  ?  180 SER   B HB3  1 
ATOM   2839  H  HG   . SER   A 1 181 ? -9.183  16.653  38.239  1.00 73.22  ?  180 SER   B HG   1 
ATOM   2840  N  N    . CYS   A 1 182 ? -5.704  18.738  39.688  1.00 53.50  ?  181 CYS   B N    1 
ATOM   2841  C  CA   . CYS   A 1 182 ? -5.094  18.374  40.956  1.00 44.97  ?  181 CYS   B CA   1 
ATOM   2842  C  C    . CYS   A 1 182 ? -4.724  19.631  41.712  1.00 40.79  ?  181 CYS   B C    1 
ATOM   2843  O  O    . CYS   A 1 182 ? -4.059  20.510  41.162  1.00 47.54  ?  181 CYS   B O    1 
ATOM   2844  C  CB   . CYS   A 1 182 ? -3.845  17.540  40.724  1.00 45.06  ?  181 CYS   B CB   1 
ATOM   2845  S  SG   . CYS   A 1 182 ? -4.225  15.846  40.384  1.00 46.71  ?  181 CYS   B SG   1 
ATOM   2846  H  H    . CYS   A 1 182 ? -5.135  18.855  39.053  1.00 64.19  ?  181 CYS   B H    1 
ATOM   2847  H  HA   . CYS   A 1 182 ? -5.723  17.857  41.482  1.00 53.96  ?  181 CYS   B HA   1 
ATOM   2848  H  HB2  . CYS   A 1 182 ? -3.359  17.899  39.965  1.00 54.07  ?  181 CYS   B HB2  1 
ATOM   2849  H  HB3  . CYS   A 1 182 ? -3.290  17.572  41.519  1.00 54.07  ?  181 CYS   B HB3  1 
ATOM   2850  H  HG   . CYS   A 1 182 ? -3.227  15.287  40.021  1.00 56.05  ?  181 CYS   B HG   1 
ATOM   2851  N  N    . LYS   A 1 183 ? -5.090  19.681  42.981  1.00 33.20  ?  182 LYS   B N    1 
ATOM   2852  C  CA   . LYS   A 1 183 ? -4.935  20.865  43.812  1.00 41.37  ?  182 LYS   B CA   1 
ATOM   2853  C  C    . LYS   A 1 183 ? -4.519  20.452  45.215  1.00 41.69  ?  182 LYS   B C    1 
ATOM   2854  O  O    . LYS   A 1 183 ? -5.105  19.534  45.796  1.00 46.10  ?  182 LYS   B O    1 
ATOM   2855  C  CB   . LYS   A 1 183 ? -6.253  21.644  43.873  1.00 45.77  ?  182 LYS   B CB   1 
ATOM   2856  C  CG   . LYS   A 1 183 ? -6.175  23.008  44.530  1.00 48.58  ?  182 LYS   B CG   1 
ATOM   2857  C  CD   . LYS   A 1 183 ? -7.582  23.520  44.891  1.00 56.08  ?  182 LYS   B CD   1 
ATOM   2858  C  CE   . LYS   A 1 183 ? -7.581  25.016  45.172  1.00 65.84  ?  182 LYS   B CE   1 
ATOM   2859  N  NZ   . LYS   A 1 183 ? -8.616  25.359  46.193  1.00 64.63  ?  182 LYS   B NZ   1 
ATOM   2860  H  H    . LYS   A 1 183 ? -5.444  19.019  43.401  1.00 39.84  ?  182 LYS   B H    1 
ATOM   2861  H  HA   . LYS   A 1 183 ? -4.238  21.433  43.447  1.00 49.64  ?  182 LYS   B HA   1 
ATOM   2862  H  HB2  . LYS   A 1 183 ? -6.570  21.779  42.966  1.00 54.92  ?  182 LYS   B HB2  1 
ATOM   2863  H  HB3  . LYS   A 1 183 ? -6.896  21.119  44.374  1.00 54.92  ?  182 LYS   B HB3  1 
ATOM   2864  H  HG2  . LYS   A 1 183 ? -5.651  22.946  45.344  1.00 58.30  ?  182 LYS   B HG2  1 
ATOM   2865  H  HG3  . LYS   A 1 183 ? -5.764  23.640  43.919  1.00 58.30  ?  182 LYS   B HG3  1 
ATOM   2866  H  HD2  . LYS   A 1 183 ? -8.184  23.349  44.150  1.00 67.30  ?  182 LYS   B HD2  1 
ATOM   2867  H  HD3  . LYS   A 1 183 ? -7.895  23.061  45.686  1.00 67.30  ?  182 LYS   B HD3  1 
ATOM   2868  H  HE2  . LYS   A 1 183 ? -6.712  25.283  45.510  1.00 79.01  ?  182 LYS   B HE2  1 
ATOM   2869  H  HE3  . LYS   A 1 183 ? -7.781  25.500  44.355  1.00 79.01  ?  182 LYS   B HE3  1 
ATOM   2870  H  HZ1  . LYS   A 1 183 ? -8.482  26.185  46.497  1.00 77.56  ?  182 LYS   B HZ1  1 
ATOM   2871  H  HZ2  . LYS   A 1 183 ? -9.428  25.312  45.832  1.00 77.56  ?  182 LYS   B HZ2  1 
ATOM   2872  H  HZ3  . LYS   A 1 183 ? -8.570  24.790  46.876  1.00 77.56  ?  182 LYS   B HZ3  1 
ATOM   2873  N  N    . ARG   A 1 184 ? -3.505  21.127  45.745  1.00 32.66  ?  183 ARG   B N    1 
ATOM   2874  C  CA   . ARG   A 1 184 ? -3.057  20.978  47.113  1.00 35.77  ?  183 ARG   B CA   1 
ATOM   2875  C  C    . ARG   A 1 184 ? -3.079  22.354  47.753  1.00 33.43  ?  183 ARG   B C    1 
ATOM   2876  O  O    . ARG   A 1 184 ? -2.830  23.354  47.088  1.00 38.95  ?  183 ARG   B O    1 
ATOM   2877  C  CB   . ARG   A 1 184 ? -1.663  20.378  47.166  1.00 43.63  ?  183 ARG   B CB   1 
ATOM   2878  C  CG   . ARG   A 1 184 ? -0.938  20.610  48.464  1.00 40.48  ?  183 ARG   B CG   1 
ATOM   2879  C  CD   . ARG   A 1 184 ? 0.352   19.751  48.493  1.00 37.63  ?  183 ARG   B CD   1 
ATOM   2880  N  NE   . ARG   A 1 184 ? -0.005  18.345  48.396  1.00 44.45  ?  183 ARG   B NE   1 
ATOM   2881  C  CZ   . ARG   A 1 184 ? 0.865   17.356  48.270  1.00 41.22  ?  183 ARG   B CZ   1 
ATOM   2882  N  NH1  . ARG   A 1 184 ? 2.163   17.579  48.259  1.00 41.62  ?  183 ARG   B NH1  1 
ATOM   2883  N  NH2  . ARG   A 1 184 ? 0.416   16.110  48.147  1.00 42.60  ?  183 ARG   B NH2  1 
ATOM   2884  H  H    . ARG   A 1 184 ? -3.043  21.705  45.306  1.00 39.19  ?  183 ARG   B H    1 
ATOM   2885  H  HA   . ARG   A 1 184 ? -3.637  20.386  47.617  1.00 42.92  ?  183 ARG   B HA   1 
ATOM   2886  H  HB2  . ARG   A 1 184 ? -1.733  19.419  47.035  1.00 52.36  ?  183 ARG   B HB2  1 
ATOM   2887  H  HB3  . ARG   A 1 184 ? -1.129  20.771  46.457  1.00 52.36  ?  183 ARG   B HB3  1 
ATOM   2888  H  HG2  . ARG   A 1 184 ? -0.695  21.546  48.543  1.00 48.58  ?  183 ARG   B HG2  1 
ATOM   2889  H  HG3  . ARG   A 1 184 ? -1.504  20.351  49.208  1.00 48.58  ?  183 ARG   B HG3  1 
ATOM   2890  H  HD2  . ARG   A 1 184 ? 0.920   19.984  47.741  1.00 45.16  ?  183 ARG   B HD2  1 
ATOM   2891  H  HD3  . ARG   A 1 184 ? 0.828   19.899  49.326  1.00 45.16  ?  183 ARG   B HD3  1 
ATOM   2892  H  HE   . ARG   A 1 184 ? -0.840  18.141  48.423  1.00 53.34  ?  183 ARG   B HE   1 
ATOM   2893  H  HH11 . ARG   A 1 184 ? 2.462   18.382  48.334  1.00 49.94  ?  183 ARG   B HH11 1 
ATOM   2894  H  HH12 . ARG   A 1 184 ? 2.712   16.922  48.176  1.00 49.94  ?  183 ARG   B HH12 1 
ATOM   2895  H  HH21 . ARG   A 1 184 ? -0.430  15.956  48.150  1.00 51.11  ?  183 ARG   B HH21 1 
ATOM   2896  H  HH22 . ARG   A 1 184 ? 0.972   15.459  48.064  1.00 51.11  ?  183 ARG   B HH22 1 
ATOM   2897  N  N    . VAL   A 1 185 ? -3.413  22.405  49.033  1.00 33.37  ?  184 VAL   B N    1 
ATOM   2898  C  CA   . VAL   A 1 185 ? -3.426  23.652  49.783  1.00 40.89  ?  184 VAL   B CA   1 
ATOM   2899  C  C    . VAL   A 1 185 ? -2.646  23.403  51.047  1.00 42.67  ?  184 VAL   B C    1 
ATOM   2900  O  O    . VAL   A 1 185 ? -2.927  22.426  51.751  1.00 38.41  ?  184 VAL   B O    1 
ATOM   2901  C  CB   . VAL   A 1 185 ? -4.852  24.129  50.114  1.00 43.07  ?  184 VAL   B CB   1 
ATOM   2902  C  CG1  . VAL   A 1 185 ? -4.804  25.396  50.936  1.00 44.66  ?  184 VAL   B CG1  1 
ATOM   2903  C  CG2  . VAL   A 1 185 ? -5.623  24.386  48.830  1.00 43.84  ?  184 VAL   B CG2  1 
ATOM   2904  H  H    . VAL   A 1 185 ? -3.640  21.718  49.498  1.00 40.05  ?  184 VAL   B H    1 
ATOM   2905  H  HA   . VAL   A 1 185 ? -3.000  24.352  49.265  1.00 49.07  ?  184 VAL   B HA   1 
ATOM   2906  H  HB   . VAL   A 1 185 ? -5.304  23.441  50.626  1.00 51.68  ?  184 VAL   B HB   1 
ATOM   2907  H  HG11 . VAL   A 1 185 ? -5.691  25.787  50.965  1.00 53.59  ?  184 VAL   B HG11 1 
ATOM   2908  H  HG12 . VAL   A 1 185 ? -4.509  25.178  51.834  1.00 53.59  ?  184 VAL   B HG12 1 
ATOM   2909  H  HG13 . VAL   A 1 185 ? -4.182  26.016  50.525  1.00 53.59  ?  184 VAL   B HG13 1 
ATOM   2910  H  HG21 . VAL   A 1 185 ? -6.507  24.718  49.054  1.00 52.61  ?  184 VAL   B HG21 1 
ATOM   2911  H  HG22 . VAL   A 1 185 ? -5.146  25.046  48.302  1.00 52.61  ?  184 VAL   B HG22 1 
ATOM   2912  H  HG23 . VAL   A 1 185 ? -5.696  23.556  48.334  1.00 52.61  ?  184 VAL   B HG23 1 
ATOM   2913  N  N    . LEU   A 1 186 ? -1.650  24.260  51.308  1.00 51.01  ?  185 LEU   B N    1 
ATOM   2914  C  CA   . LEU   A 1 186 ? -0.746  24.153  52.442  1.00 49.70  ?  185 LEU   B CA   1 
ATOM   2915  C  C    . LEU   A 1 186 ? -0.787  25.409  53.305  1.00 51.44  ?  185 LEU   B C    1 
ATOM   2916  O  O    . LEU   A 1 186 ? -1.047  26.519  52.828  1.00 48.95  ?  185 LEU   B O    1 
ATOM   2917  C  CB   . LEU   A 1 186 ? 0.703   23.939  51.975  1.00 53.05  ?  185 LEU   B CB   1 
ATOM   2918  C  CG   . LEU   A 1 186 ? 0.878   22.722  51.087  1.00 55.57  ?  185 LEU   B CG   1 
ATOM   2919  C  CD1  . LEU   A 1 186 ? 1.984   22.930  50.079  1.00 45.00  ?  185 LEU   B CD1  1 
ATOM   2920  C  CD2  . LEU   A 1 186 ? 1.135   21.500  51.945  1.00 53.90  ?  185 LEU   B CD2  1 
ATOM   2921  H  H    . LEU   A 1 186 ? -1.476  24.942  50.814  1.00 61.22  ?  185 LEU   B H    1 
ATOM   2922  H  HA   . LEU   A 1 186 ? -1.035  23.402  52.983  1.00 59.64  ?  185 LEU   B HA   1 
ATOM   2923  H  HB2  . LEU   A 1 186 ? 0.987   24.718  51.471  1.00 63.66  ?  185 LEU   B HB2  1 
ATOM   2924  H  HB3  . LEU   A 1 186 ? 1.268   23.823  52.754  1.00 63.66  ?  185 LEU   B HB3  1 
ATOM   2925  H  HG   . LEU   A 1 186 ? 0.064   22.575  50.579  1.00 66.68  ?  185 LEU   B HG   1 
ATOM   2926  H  HD11 . LEU   A 1 186 ? 2.058   22.138  49.523  1.00 54.01  ?  185 LEU   B HD11 1 
ATOM   2927  H  HD12 . LEU   A 1 186 ? 1.770   23.700  49.529  1.00 54.01  ?  185 LEU   B HD12 1 
ATOM   2928  H  HD13 . LEU   A 1 186 ? 2.818   23.082  50.551  1.00 54.01  ?  185 LEU   B HD13 1 
ATOM   2929  H  HD21 . LEU   A 1 186 ? 1.232   20.725  51.370  1.00 64.68  ?  185 LEU   B HD21 1 
ATOM   2930  H  HD22 . LEU   A 1 186 ? 1.949   21.638  52.454  1.00 64.68  ?  185 LEU   B HD22 1 
ATOM   2931  H  HD23 . LEU   A 1 186 ? 0.386   21.373  52.547  1.00 64.68  ?  185 LEU   B HD23 1 
ATOM   2932  N  N    . ASN   A 1 187 ? -0.413  25.222  54.572  1.00 60.35  ?  186 ASN   B N    1 
ATOM   2933  C  CA   . ASN   A 1 187 ? -0.370  26.288  55.566  1.00 68.09  ?  186 ASN   B CA   1 
ATOM   2934  C  C    . ASN   A 1 187 ? 0.879   26.151  56.429  1.00 67.56  ?  186 ASN   B C    1 
ATOM   2935  O  O    . ASN   A 1 187 ? 1.176   25.052  56.904  1.00 64.26  ?  186 ASN   B O    1 
ATOM   2936  C  CB   . ASN   A 1 187 ? -1.640  26.222  56.426  1.00 62.08  ?  186 ASN   B CB   1 
ATOM   2937  C  CG   . ASN   A 1 187 ? -1.900  27.497  57.178  1.00 72.43  ?  186 ASN   B CG   1 
ATOM   2938  O  OD1  . ASN   A 1 187 ? -1.839  28.595  56.607  1.00 72.01  ?  186 ASN   B OD1  1 
ATOM   2939  N  ND2  . ASN   A 1 187 ? -2.192  27.366  58.476  1.00 75.47  ?  186 ASN   B ND2  1 
ATOM   2940  H  H    . ASN   A 1 187 ? -0.173  24.459  54.889  1.00 72.42  ?  186 ASN   B H    1 
ATOM   2941  H  HA   . ASN   A 1 187 ? -0.310  27.154  55.134  1.00 81.71  ?  186 ASN   B HA   1 
ATOM   2942  H  HB2  . ASN   A 1 187 ? -2.402  26.052  55.850  1.00 74.49  ?  186 ASN   B HB2  1 
ATOM   2943  H  HB3  . ASN   A 1 187 ? -1.546  25.506  57.073  1.00 74.49  ?  186 ASN   B HB3  1 
ATOM   2944  H  HD21 . ASN   A 1 187 ? -2.222  26.585  58.834  1.00 90.57  ?  186 ASN   B HD21 1 
ATOM   2945  H  HD22 . ASN   A 1 187 ? -2.350  28.064  58.953  1.00 90.57  ?  186 ASN   B HD22 1 
ATOM   2946  N  N    . VAL   A 1 188 ? 1.641   27.240  56.561  1.00 78.04  ?  187 VAL   B N    1 
ATOM   2947  C  CA   . VAL   A 1 188 ? 2.819   27.253  57.347  1.00 86.30  ?  187 VAL   B CA   1 
ATOM   2948  C  C    . VAL   A 1 188 ? 2.611   28.242  58.502  1.00 84.31  ?  187 VAL   B C    1 
ATOM   2949  O  O    . VAL   A 1 188 ? 2.359   29.405  58.267  1.00 83.30  ?  187 VAL   B O    1 
ATOM   2950  C  CB   . VAL   A 1 188 ? 4.056   27.579  56.513  1.00 85.85  ?  187 VAL   B CB   1 
ATOM   2951  C  CG1  . VAL   A 1 188 ? 3.995   26.836  55.208  1.00 72.03  ?  187 VAL   B CG1  1 
ATOM   2952  C  CG2  . VAL   A 1 188 ? 4.137   29.060  56.260  1.00 83.03  ?  187 VAL   B CG2  1 
ATOM   2953  H  H    . VAL   A 1 188 ? 1.557   28.044  56.254  1.00 93.65  ?  187 VAL   B H    1 
ATOM   2954  H  HA   . VAL   A 1 188 ? 2.950   26.343  57.683  1.00 103.56 ?  187 VAL   B HA   1 
ATOM   2955  H  HB   . VAL   A 1 188 ? 4.862   27.299  56.995  1.00 103.01 ?  187 VAL   B HB   1 
ATOM   2956  H  HG11 . VAL   A 1 188 ? 4.751   27.087  54.671  1.00 86.43  ?  187 VAL   B HG11 1 
ATOM   2957  H  HG12 . VAL   A 1 188 ? 4.017   25.893  55.384  1.00 86.43  ?  187 VAL   B HG12 1 
ATOM   2958  H  HG13 . VAL   A 1 188 ? 3.181   27.067  54.755  1.00 86.43  ?  187 VAL   B HG13 1 
ATOM   2959  H  HG21 . VAL   A 1 188 ? 4.466   29.207  55.370  1.00 99.63  ?  187 VAL   B HG21 1 
ATOM   2960  H  HG22 . VAL   A 1 188 ? 3.259   29.439  56.353  1.00 99.63  ?  187 VAL   B HG22 1 
ATOM   2961  H  HG23 . VAL   A 1 188 ? 4.733   29.454  56.901  1.00 99.63  ?  187 VAL   B HG23 1 
ATOM   2962  N  N    . VAL   A 1 189 ? 2.684   27.779  59.741  1.00 84.89  ?  188 VAL   B N    1 
ATOM   2963  C  CA   . VAL   A 1 189 ? 2.464   28.654  60.865  1.00 93.71  ?  188 VAL   B CA   1 
ATOM   2964  C  C    . VAL   A 1 189 ? 3.688   28.829  61.773  1.00 95.51  ?  188 VAL   B C    1 
ATOM   2965  O  O    . VAL   A 1 189 ? 4.390   27.872  62.070  1.00 88.32  ?  188 VAL   B O    1 
ATOM   2966  C  CB   . VAL   A 1 189 ? 1.339   28.129  61.756  1.00 79.04  ?  188 VAL   B CB   1 
ATOM   2967  C  CG1  . VAL   A 1 189 ? 0.256   27.491  60.925  1.00 69.59  ?  188 VAL   B CG1  1 
ATOM   2968  C  CG2  . VAL   A 1 189 ? 1.884   27.138  62.761  1.00 74.76  ?  188 VAL   B CG2  1 
ATOM   2969  H  H    . VAL   A 1 189 ? 2.860   26.972  59.984  1.00 101.86 ?  188 VAL   B H    1 
ATOM   2970  H  HA   . VAL   A 1 189 ? 2.168   29.512  60.496  1.00 112.45 ?  188 VAL   B HA   1 
ATOM   2971  H  HB   . VAL   A 1 189 ? 0.944   28.878  62.250  1.00 94.85  ?  188 VAL   B HB   1 
ATOM   2972  H  HG11 . VAL   A 1 189 ? -0.396  27.099  61.509  1.00 83.51  ?  188 VAL   B HG11 1 
ATOM   2973  H  HG12 . VAL   A 1 189 ? -0.156  28.165  60.379  1.00 83.51  ?  188 VAL   B HG12 1 
ATOM   2974  H  HG13 . VAL   A 1 189 ? 0.648   26.814  60.369  1.00 83.51  ?  188 VAL   B HG13 1 
ATOM   2975  H  HG21 . VAL   A 1 189 ? 1.168   26.577  63.067  1.00 89.71  ?  188 VAL   B HG21 1 
ATOM   2976  H  HG22 . VAL   A 1 189 ? 2.560   26.604  62.337  1.00 89.71  ?  188 VAL   B HG22 1 
ATOM   2977  H  HG23 . VAL   A 1 189 ? 2.261   27.619  63.501  1.00 89.71  ?  188 VAL   B HG23 1 
ATOM   2978  N  N    . CYS   A 1 190 ? 3.924   30.056  62.233  1.00 117.06 ?  189 CYS   B N    1 
ATOM   2979  C  CA   . CYS   A 1 190 ? 5.042   30.350  63.120  1.00 138.31 ?  189 CYS   B CA   1 
ATOM   2980  C  C    . CYS   A 1 190 ? 4.540   30.739  64.514  1.00 132.09 ?  189 CYS   B C    1 
ATOM   2981  O  O    . CYS   A 1 190 ? 3.377   31.077  64.712  1.00 142.20 ?  189 CYS   B O    1 
ATOM   2982  C  CB   . CYS   A 1 190 ? 5.899   31.470  62.534  1.00 154.94 ?  189 CYS   B CB   1 
ATOM   2983  S  SG   . CYS   A 1 190 ? 7.139   32.092  63.672  1.00 118.24 ?  189 CYS   B SG   1 
ATOM   2984  H  H    . CYS   A 1 190 ? 3.458   30.760  62.069  1.00 140.47 ?  189 CYS   B H    1 
ATOM   2985  H  HA   . CYS   A 1 190 ? 5.602   29.550  63.208  1.00 165.97 ?  189 CYS   B HA   1 
ATOM   2986  N  N    . LYS   A 1 191 ? 5.397   30.622  65.505  1.00 147.35 ?  190 LYS   B N    1 
ATOM   2987  C  CA   . LYS   A 1 191 ? 5.006   31.027  66.835  1.00 147.81 ?  190 LYS   B CA   1 
ATOM   2988  C  C    . LYS   A 1 191 ? 5.107   32.536  66.879  1.00 149.19 ?  190 LYS   B C    1 
ATOM   2989  O  O    . LYS   A 1 191 ? 4.275   33.198  67.482  1.00 170.29 ?  190 LYS   B O    1 
ATOM   2990  C  CB   . LYS   A 1 191 ? 5.903   30.399  67.896  1.00 155.70 ?  190 LYS   B CB   1 
ATOM   2991  H  H    . LYS   A 1 191 ? 6.189   30.291  65.439  1.00 176.81 ?  190 LYS   B H    1 
ATOM   2992  H  HA   . LYS   A 1 191 ? 4.077   30.765  67.007  1.00 177.38 ?  190 LYS   B HA   1 
ATOM   2993  N  N    . THR   A 1 192 ? 6.127   33.060  66.202  1.00 159.88 ?  191 THR   B N    1 
ATOM   2994  C  CA   . THR   A 1 192 ? 6.400   34.478  66.121  1.00 157.34 ?  191 THR   B CA   1 
ATOM   2995  C  C    . THR   A 1 192 ? 5.712   35.143  64.922  1.00 149.38 ?  191 THR   B C    1 
ATOM   2996  O  O    . THR   A 1 192 ? 4.896   36.031  65.100  1.00 135.07 ?  191 THR   B O    1 
ATOM   2997  C  CB   . THR   A 1 192 ? 7.912   34.666  66.086  1.00 139.72 ?  191 THR   B CB   1 
ATOM   2998  O  OG1  . THR   A 1 192 ? 8.491   33.817  67.091  1.00 148.08 ?  191 THR   B OG1  1 
ATOM   2999  C  CG2  . THR   A 1 192 ? 8.270   36.111  66.349  1.00 131.72 ?  191 THR   B CG2  1 
ATOM   3000  H  H    . THR   A 1 192 ? 6.715   32.603  65.778  1.00 191.86 ?  191 THR   B H    1 
ATOM   3001  H  HA   . THR   A 1 192 ? 6.064   34.909  66.934  1.00 188.81 ?  191 THR   B HA   1 
ATOM   3002  H  HB   . THR   A 1 192 ? 8.266   34.413  65.220  1.00 167.67 ?  191 THR   B HB   1 
ATOM   3003  H  HG1  . THR   A 1 192 ? 7.906   33.540  67.595  1.00 177.69 ?  191 THR   B HG1  1 
ATOM   3004  H  HG21 . THR   A 1 192 ? 9.162   36.168  66.699  1.00 158.07 ?  191 THR   B HG21 1 
ATOM   3005  H  HG22 . THR   A 1 192 ? 8.222   36.616  65.534  1.00 158.07 ?  191 THR   B HG22 1 
ATOM   3006  H  HG23 . THR   A 1 192 ? 7.662   36.490  66.988  1.00 158.07 ?  191 THR   B HG23 1 
ATOM   3007  N  N    . CYS   A 1 193 ? 5.995   34.697  63.701  1.00 139.47 ?  192 CYS   B N    1 
ATOM   3008  C  CA   . CYS   A 1 193 ? 5.291   35.228  62.516  1.00 133.01 ?  192 CYS   B CA   1 
ATOM   3009  C  C    . CYS   A 1 193 ? 3.937   34.501  62.315  1.00 129.63 ?  192 CYS   B C    1 
ATOM   3010  O  O    . CYS   A 1 193 ? 3.579   33.621  63.085  1.00 126.52 ?  192 CYS   B O    1 
ATOM   3011  C  CB   . CYS   A 1 193 ? 6.162   35.100  61.269  1.00 30.00  ?  192 CYS   B CB   1 
ATOM   3012  S  SG   . CYS   A 1 193 ? 5.389   35.674  59.741  1.00 30.00  ?  192 CYS   B SG   1 
ATOM   3013  H  H    . CYS   A 1 193 ? 6.591   34.104  63.525  1.00 167.37 ?  192 CYS   B H    1 
ATOM   3014  H  HA   . CYS   A 1 193 ? 5.104   36.180  62.656  1.00 159.61 ?  192 CYS   B HA   1 
ATOM   3015  N  N    . GLY   A 1 194 ? 3.162   34.832  61.291  1.00 119.44 ?  193 GLY   B N    1 
ATOM   3016  C  CA   . GLY   A 1 194 ? 1.877   34.154  61.140  1.00 112.56 ?  193 GLY   B CA   1 
ATOM   3017  C  C    . GLY   A 1 194 ? 1.598   33.226  59.963  1.00 99.69  ?  193 GLY   B C    1 
ATOM   3018  O  O    . GLY   A 1 194 ? 2.458   32.885  59.161  1.00 99.70  ?  193 GLY   B O    1 
ATOM   3019  H  H    . GLY   A 1 194 ? 3.340   35.421  60.691  1.00 143.33 ?  193 GLY   B H    1 
ATOM   3020  H  HA2  . GLY   A 1 194 ? 1.730   33.631  61.943  1.00 135.08 ?  193 GLY   B HA2  1 
ATOM   3021  H  HA3  . GLY   A 1 194 ? 1.191   34.839  61.120  1.00 135.08 ?  193 GLY   B HA3  1 
ATOM   3022  N  N    . GLN   A 1 195 ? 0.337   32.817  59.900  1.00 96.86  ?  194 GLN   B N    1 
ATOM   3023  C  CA   . GLN   A 1 195 ? -0.207  31.968  58.853  1.00 91.12  ?  194 GLN   B CA   1 
ATOM   3024  C  C    . GLN   A 1 195 ? 0.233   32.404  57.469  1.00 81.17  ?  194 GLN   B C    1 
ATOM   3025  O  O    . GLN   A 1 195 ? 0.005   33.532  57.110  1.00 89.38  ?  194 GLN   B O    1 
ATOM   3026  C  CB   . GLN   A 1 195 ? -1.725  32.142  58.859  1.00 96.44  ?  194 GLN   B CB   1 
ATOM   3027  C  CG   . GLN   A 1 195 ? -2.561  31.055  59.505  1.00 87.21  ?  194 GLN   B CG   1 
ATOM   3028  C  CD   . GLN   A 1 195 ? -3.771  30.656  58.642  1.00 104.45 ?  194 GLN   B CD   1 
ATOM   3029  O  OE1  . GLN   A 1 195 ? -3.759  30.799  57.418  1.00 121.24 ?  194 GLN   B OE1  1 
ATOM   3030  N  NE2  . GLN   A 1 195 ? -4.829  30.184  59.287  1.00 102.90 ?  194 GLN   B NE2  1 
ATOM   3031  H  H    . GLN   A 1 195 ? -0.254  33.031  60.488  1.00 116.23 ?  194 GLN   B H    1 
ATOM   3032  H  HA   . GLN   A 1 195 ? 0.015   31.029  59.023  1.00 109.35 ?  194 GLN   B HA   1 
ATOM   3033  H  HB2  . GLN   A 1 195 ? -1.930  32.969  59.322  1.00 115.73 ?  194 GLN   B HB2  1 
ATOM   3034  H  HB3  . GLN   A 1 195 ? -2.020  32.213  57.937  1.00 115.73 ?  194 GLN   B HB3  1 
ATOM   3035  H  HG2  . GLN   A 1 195 ? -1.987  30.305  59.683  1.00 104.65 ?  194 GLN   B HG2  1 
ATOM   3036  H  HG3  . GLN   A 1 195 ? -2.908  31.396  60.344  1.00 104.65 ?  194 GLN   B HG3  1 
ATOM   3037  H  HE21 . GLN   A 1 195 ? -4.787  30.039  60.134  1.00 123.48 ?  194 GLN   B HE21 1 
ATOM   3038  H  HE22 . GLN   A 1 195 ? -5.558  30.024  58.860  1.00 123.48 ?  194 GLN   B HE22 1 
ATOM   3039  N  N    . GLN   A 1 196 ? 0.850   31.535  56.682  1.00 80.96  ?  195 GLN   B N    1 
ATOM   3040  C  CA   . GLN   A 1 196 ? 1.211   31.895  55.318  1.00 88.77  ?  195 GLN   B CA   1 
ATOM   3041  C  C    . GLN   A 1 196 ? 0.739   30.771  54.444  1.00 80.31  ?  195 GLN   B C    1 
ATOM   3042  O  O    . GLN   A 1 196 ? 1.388   29.759  54.296  1.00 76.70  ?  195 GLN   B O    1 
ATOM   3043  C  CB   . GLN   A 1 196 ? 2.693   32.103  55.126  1.00 100.50 ?  195 GLN   B CB   1 
ATOM   3044  C  CG   . GLN   A 1 196 ? 2.980   33.241  54.165  1.00 96.63  ?  195 GLN   B CG   1 
ATOM   3045  C  CD   . GLN   A 1 196 ? 3.685   32.779  52.912  1.00 91.72  ?  195 GLN   B CD   1 
ATOM   3046  O  OE1  . GLN   A 1 196 ? 4.520   31.886  52.954  1.00 104.99 ?  195 GLN   B OE1  1 
ATOM   3047  N  NE2  . GLN   A 1 196 ? 3.351   33.394  51.786  1.00 89.92  ?  195 GLN   B NE2  1 
ATOM   3048  H  H    . GLN   A 1 196 ? 1.077   30.735  56.898  1.00 97.15  ?  195 GLN   B H    1 
ATOM   3049  H  HA   . GLN   A 1 196 ? 0.786   32.745  55.075  1.00 106.52 ?  195 GLN   B HA   1 
ATOM   3050  H  HB2  . GLN   A 1 196 ? 3.104   32.311  55.980  1.00 120.60 ?  195 GLN   B HB2  1 
ATOM   3051  H  HB3  . GLN   A 1 196 ? 3.079   31.297  54.752  1.00 120.60 ?  195 GLN   B HB3  1 
ATOM   3052  H  HG2  . GLN   A 1 196 ? 2.141   33.653  53.903  1.00 115.95 ?  195 GLN   B HG2  1 
ATOM   3053  H  HG3  . GLN   A 1 196 ? 3.547   33.892  54.606  1.00 115.95 ?  195 GLN   B HG3  1 
ATOM   3054  H  HE21 . GLN   A 1 196 ? 2.554   33.700  51.683  1.00 107.91 ?  195 GLN   B HE21 1 
ATOM   3055  H  HE22 . GLN   A 1 196 ? 3.931   33.486  51.158  1.00 107.91 ?  195 GLN   B HE22 1 
ATOM   3056  N  N    . GLN   A 1 197 ? -0.470  30.890  53.978  1.00 73.02  ?  196 GLN   B N    1 
ATOM   3057  C  CA   . GLN   A 1 197 ? -1.070  29.864  53.124  1.00 70.33  ?  196 GLN   B CA   1 
ATOM   3058  C  C    . GLN   A 1 197 ? -0.530  29.844  51.684  1.00 67.54  ?  196 GLN   B C    1 
ATOM   3059  O  O    . GLN   A 1 197 ? -0.258  30.894  51.098  1.00 59.78  ?  196 GLN   B O    1 
ATOM   3060  C  CB   . GLN   A 1 197 ? -2.590  30.041  53.090  1.00 68.84  ?  196 GLN   B CB   1 
ATOM   3061  C  CG   . GLN   A 1 197 ? -3.337  28.855  52.500  1.00 68.52  ?  196 GLN   B CG   1 
ATOM   3062  C  CD   . GLN   A 1 197 ? -4.789  28.802  52.937  1.00 65.23  ?  196 GLN   B CD   1 
ATOM   3063  O  OE1  . GLN   A 1 197 ? -5.092  28.494  54.089  1.00 58.66  ?  196 GLN   B OE1  1 
ATOM   3064  N  NE2  . GLN   A 1 197 ? -5.696  29.103  52.014  1.00 49.69  ?  196 GLN   B NE2  1 
ATOM   3065  H  H    . GLN   A 1 197 ? -1.049  31.387  54.376  1.00 87.62  ?  196 GLN   B H    1 
ATOM   3066  H  HA   . GLN   A 1 197 ? -0.892  29.004  53.558  1.00 84.40  ?  196 GLN   B HA   1 
ATOM   3067  H  HB2  . GLN   A 1 197 ? -2.908  30.167  53.997  1.00 82.60  ?  196 GLN   B HB2  1 
ATOM   3068  H  HB3  . GLN   A 1 197 ? -2.802  30.822  52.556  1.00 82.60  ?  196 GLN   B HB3  1 
ATOM   3069  H  HG2  . GLN   A 1 197 ? -3.316  28.917  51.532  1.00 82.23  ?  196 GLN   B HG2  1 
ATOM   3070  H  HG3  . GLN   A 1 197 ? -2.909  28.034  52.789  1.00 82.23  ?  196 GLN   B HG3  1 
ATOM   3071  H  HE21 . GLN   A 1 197 ? -5.446  29.359  51.233  1.00 59.63  ?  196 GLN   B HE21 1 
ATOM   3072  H  HE22 . GLN   A 1 197 ? -6.534  29.041  52.199  1.00 59.63  ?  196 GLN   B HE22 1 
ATOM   3073  N  N    . THR   A 1 198 ? -0.398  28.649  51.106  1.00 61.84  ?  197 THR   B N    1 
ATOM   3074  C  CA   . THR   A 1 198 ? 0.100   28.500  49.744  1.00 59.34  ?  197 THR   B CA   1 
ATOM   3075  C  C    . THR   A 1 198 ? -0.780  27.506  48.990  1.00 55.31  ?  197 THR   B C    1 
ATOM   3076  O  O    . THR   A 1 198 ? -1.408  26.639  49.599  1.00 55.65  ?  197 THR   B O    1 
ATOM   3077  C  CB   . THR   A 1 198 ? 1.553   27.983  49.726  1.00 70.45  ?  197 THR   B CB   1 
ATOM   3078  O  OG1  . THR   A 1 198 ? 2.282   28.530  50.833  1.00 62.39  ?  197 THR   B OG1  1 
ATOM   3079  C  CG2  . THR   A 1 198 ? 2.244   28.371  48.426  1.00 66.32  ?  197 THR   B CG2  1 
ATOM   3080  H  H    . THR   A 1 198 ? -0.599  27.893  51.463  1.00 74.21  ?  197 THR   B H    1 
ATOM   3081  H  HA   . THR   A 1 198 ? 0.068   29.365  49.284  1.00 71.20  ?  197 THR   B HA   1 
ATOM   3082  H  HB   . THR   A 1 198 ? 1.550   27.016  49.791  1.00 84.54  ?  197 THR   B HB   1 
ATOM   3083  H  HG1  . THR   A 1 198 ? 3.055   28.692  50.611  1.00 74.87  ?  197 THR   B HG1  1 
ATOM   3084  H  HG21 . THR   A 1 198 ? 3.196   28.293  48.523  1.00 79.58  ?  197 THR   B HG21 1 
ATOM   3085  H  HG22 . THR   A 1 198 ? 1.954   27.792  47.717  1.00 79.58  ?  197 THR   B HG22 1 
ATOM   3086  H  HG23 . THR   A 1 198 ? 2.026   29.278  48.199  1.00 79.58  ?  197 THR   B HG23 1 
ATOM   3087  N  N    . THR   A 1 199 ? -0.828  27.633  47.668  1.00 51.81  ?  198 THR   B N    1 
ATOM   3088  C  CA   . THR   A 1 199 ? -1.628  26.734  46.846  1.00 48.19  ?  198 THR   B CA   1 
ATOM   3089  C  C    . THR   A 1 199 ? -0.784  26.187  45.690  1.00 51.75  ?  198 THR   B C    1 
ATOM   3090  O  O    . THR   A 1 199 ? -0.004  26.927  45.091  1.00 53.29  ?  198 THR   B O    1 
ATOM   3091  C  CB   . THR   A 1 199 ? -2.862  27.449  46.266  1.00 53.92  ?  198 THR   B CB   1 
ATOM   3092  O  OG1  . THR   A 1 199 ? -3.574  28.111  47.318  1.00 55.89  ?  198 THR   B OG1  1 
ATOM   3093  C  CG2  . THR   A 1 199 ? -3.785  26.450  45.579  1.00 46.22  ?  198 THR   B CG2  1 
ATOM   3094  H  H    . THR   A 1 199 ? -0.405  28.234  47.221  1.00 62.17  ?  198 THR   B H    1 
ATOM   3095  H  HA   . THR   A 1 199 ? -1.943  26.003  47.418  1.00 57.83  ?  198 THR   B HA   1 
ATOM   3096  H  HB   . THR   A 1 199 ? -2.574  28.104  45.611  1.00 64.71  ?  198 THR   B HB   1 
ATOM   3097  H  HG1  . THR   A 1 199 ? -3.987  27.561  47.766  1.00 67.07  ?  198 THR   B HG1  1 
ATOM   3098  H  HG21 . THR   A 1 199 ? -4.627  26.865  45.378  1.00 55.47  ?  198 THR   B HG21 1 
ATOM   3099  H  HG22 . THR   A 1 199 ? -3.387  26.140  44.763  1.00 55.47  ?  198 THR   B HG22 1 
ATOM   3100  H  HG23 . THR   A 1 199 ? -3.939  25.697  46.155  1.00 55.47  ?  198 THR   B HG23 1 
ATOM   3101  N  N    . LEU   A 1 200 ? -0.935  24.901  45.374  1.00 50.34  ?  199 LEU   B N    1 
ATOM   3102  C  CA   . LEU   A 1 200 ? -0.171  24.289  44.292  1.00 39.97  ?  199 LEU   B CA   1 
ATOM   3103  C  C    . LEU   A 1 200 ? -1.091  23.512  43.353  1.00 45.39  ?  199 LEU   B C    1 
ATOM   3104  O  O    . LEU   A 1 200 ? -2.169  23.073  43.752  1.00 43.79  ?  199 LEU   B O    1 
ATOM   3105  C  CB   . LEU   A 1 200 ? 0.896   23.349  44.859  1.00 42.64  ?  199 LEU   B CB   1 
ATOM   3106  C  CG   . LEU   A 1 200 ? 1.782   23.905  45.977  1.00 44.74  ?  199 LEU   B CG   1 
ATOM   3107  C  CD1  . LEU   A 1 200 ? 2.551   22.783  46.658  1.00 43.65  ?  199 LEU   B CD1  1 
ATOM   3108  C  CD2  . LEU   A 1 200 ? 2.737   24.956  45.433  1.00 48.39  ?  199 LEU   B CD2  1 
ATOM   3109  H  H    . LEU   A 1 200 ? -1.472  24.348  45.756  1.00 60.41  ?  199 LEU   B H    1 
ATOM   3110  H  HA   . LEU   A 1 200 ? 0.279   24.992  43.778  1.00 47.96  ?  199 LEU   B HA   1 
ATOM   3111  H  HB2  . LEU   A 1 200 ? 0.450   22.563  45.212  1.00 51.17  ?  199 LEU   B HB2  1 
ATOM   3112  H  HB3  . LEU   A 1 200 ? 1.483   23.084  44.133  1.00 51.17  ?  199 LEU   B HB3  1 
ATOM   3113  H  HG   . LEU   A 1 200 ? 1.222   24.327  46.647  1.00 53.69  ?  199 LEU   B HG   1 
ATOM   3114  H  HD11 . LEU   A 1 200 ? 3.134   23.161  47.321  1.00 52.38  ?  199 LEU   B HD11 1 
ATOM   3115  H  HD12 . LEU   A 1 200 ? 1.927   22.184  47.075  1.00 52.38  ?  199 LEU   B HD12 1 
ATOM   3116  H  HD13 . LEU   A 1 200 ? 3.066   22.314  45.999  1.00 52.38  ?  199 LEU   B HD13 1 
ATOM   3117  H  HD21 . LEU   A 1 200 ? 3.248   25.318  46.161  1.00 58.06  ?  199 LEU   B HD21 1 
ATOM   3118  H  HD22 . LEU   A 1 200 ? 3.323   24.544  44.794  1.00 58.06  ?  199 LEU   B HD22 1 
ATOM   3119  H  HD23 . LEU   A 1 200 ? 2.228   25.653  45.011  1.00 58.06  ?  199 LEU   B HD23 1 
ATOM   3120  N  N    . LYS   A 1 201 ? -0.657  23.340  42.107  1.00 42.53  ?  200 LYS   B N    1 
ATOM   3121  C  CA   . LYS   A 1 201 ? -1.438  22.613  41.111  1.00 38.68  ?  200 LYS   B CA   1 
ATOM   3122  C  C    . LYS   A 1 201 ? -0.512  21.860  40.161  1.00 44.54  ?  200 LYS   B C    1 
ATOM   3123  O  O    . LYS   A 1 201 ? 0.672   22.178  40.053  1.00 56.12  ?  200 LYS   B O    1 
ATOM   3124  C  CB   . LYS   A 1 201 ? -2.319  23.576  40.310  1.00 44.76  ?  200 LYS   B CB   1 
ATOM   3125  C  CG   . LYS   A 1 201 ? -3.597  23.993  41.018  1.00 48.86  ?  200 LYS   B CG   1 
ATOM   3126  C  CD   . LYS   A 1 201 ? -4.757  24.123  40.043  1.00 58.83  ?  200 LYS   B CD   1 
ATOM   3127  C  CE   . LYS   A 1 201 ? -5.841  25.037  40.591  1.00 71.91  ?  200 LYS   B CE   1 
ATOM   3128  N  NZ   . LYS   A 1 201 ? -5.391  26.454  40.677  1.00 72.57  ?  200 LYS   B NZ   1 
ATOM   3129  H  H    . LYS   A 1 201 ? 0.095   23.634  41.809  1.00 51.04  ?  200 LYS   B H    1 
ATOM   3130  H  HA   . LYS   A 1 201 ? -2.017  21.962  41.562  1.00 46.42  ?  200 LYS   B HA   1 
ATOM   3131  H  HB2  . LYS   A 1 201 ? -1.810  24.379  40.119  1.00 53.72  ?  200 LYS   B HB2  1 
ATOM   3132  H  HB3  . LYS   A 1 201 ? -2.577  23.147  39.479  1.00 53.72  ?  200 LYS   B HB3  1 
ATOM   3133  H  HG2  . LYS   A 1 201 ? -3.830  23.324  41.681  1.00 58.63  ?  200 LYS   B HG2  1 
ATOM   3134  H  HG3  . LYS   A 1 201 ? -3.460  24.854  41.443  1.00 58.63  ?  200 LYS   B HG3  1 
ATOM   3135  H  HD2  . LYS   A 1 201 ? -4.434  24.499  39.209  1.00 70.60  ?  200 LYS   B HD2  1 
ATOM   3136  H  HD3  . LYS   A 1 201 ? -5.146  23.248  39.888  1.00 70.60  ?  200 LYS   B HD3  1 
ATOM   3137  H  HE2  . LYS   A 1 201 ? -6.615  25.000  40.007  1.00 86.29  ?  200 LYS   B HE2  1 
ATOM   3138  H  HE3  . LYS   A 1 201 ? -6.081  24.742  41.483  1.00 86.29  ?  200 LYS   B HE3  1 
ATOM   3139  H  HZ1  . LYS   A 1 201 ? -6.040  26.975  41.156  1.00 87.08  ?  200 LYS   B HZ1  1 
ATOM   3140  H  HZ2  . LYS   A 1 201 ? -4.551  26.502  41.137  1.00 87.08  ?  200 LYS   B HZ2  1 
ATOM   3141  H  HZ3  . LYS   A 1 201 ? -5.287  26.820  39.796  1.00 87.08  ?  200 LYS   B HZ3  1 
ATOM   3142  N  N    . GLY   A 1 202 ? -1.054  20.858  39.476  1.00 44.18  ?  201 GLY   B N    1 
ATOM   3143  C  CA   . GLY   A 1 202 ? -0.274  20.076  38.536  1.00 44.34  ?  201 GLY   B CA   1 
ATOM   3144  C  C    . GLY   A 1 202 ? 0.474   18.942  39.222  1.00 41.10  ?  201 GLY   B C    1 
ATOM   3145  O  O    . GLY   A 1 202 ? -0.093  18.264  40.079  1.00 44.98  ?  201 GLY   B O    1 
ATOM   3146  H  H    . GLY   A 1 202 ? -1.875  20.611  39.542  1.00 53.02  ?  201 GLY   B H    1 
ATOM   3147  H  HA2  . GLY   A 1 202 ? -0.869  19.690  37.874  1.00 53.21  ?  201 GLY   B HA2  1 
ATOM   3148  H  HA3  . GLY   A 1 202 ? 0.337   20.676  38.080  1.00 53.21  ?  201 GLY   B HA3  1 
ATOM   3149  N  N    . VAL   A 1 203 ? 1.739   18.724  38.859  1.00 42.22  ?  202 VAL   B N    1 
ATOM   3150  C  CA   . VAL   A 1 203 ? 2.533   17.658  39.459  1.00 40.49  ?  202 VAL   B CA   1 
ATOM   3151  C  C    . VAL   A 1 203 ? 3.074   18.041  40.836  1.00 42.57  ?  202 VAL   B C    1 
ATOM   3152  O  O    . VAL   A 1 203 ? 3.491   17.176  41.606  1.00 39.02  ?  202 VAL   B O    1 
ATOM   3153  C  CB   . VAL   A 1 203 ? 3.720   17.277  38.555  1.00 45.14  ?  202 VAL   B CB   1 
ATOM   3154  C  CG1  . VAL   A 1 203 ? 4.545   18.509  38.217  1.00 50.15  ?  202 VAL   B CG1  1 
ATOM   3155  C  CG2  . VAL   A 1 203 ? 4.580   16.217  39.226  1.00 41.37  ?  202 VAL   B CG2  1 
ATOM   3156  H  H    . VAL   A 1 203 ? 2.177   19.163  38.263  1.00 50.67  ?  202 VAL   B H    1 
ATOM   3157  H  HA   . VAL   A 1 203 ? 1.969   16.863  39.566  1.00 48.59  ?  202 VAL   B HA   1 
ATOM   3158  H  HB   . VAL   A 1 203 ? 3.377   16.903  37.717  1.00 54.17  ?  202 VAL   B HB   1 
ATOM   3159  H  HG11 . VAL   A 1 203 ? 5.148   18.294  37.501  1.00 60.18  ?  202 VAL   B HG11 1 
ATOM   3160  H  HG12 . VAL   A 1 203 ? 3.955   19.216  37.948  1.00 60.18  ?  202 VAL   B HG12 1 
ATOM   3161  H  HG13 . VAL   A 1 203 ? 5.042   18.774  38.994  1.00 60.18  ?  202 VAL   B HG13 1 
ATOM   3162  H  HG21 . VAL   A 1 203 ? 5.202   15.868  38.583  1.00 49.64  ?  202 VAL   B HG21 1 
ATOM   3163  H  HG22 . VAL   A 1 203 ? 5.055   16.618  39.957  1.00 49.64  ?  202 VAL   B HG22 1 
ATOM   3164  H  HG23 . VAL   A 1 203 ? 4.012   15.513  39.550  1.00 49.64  ?  202 VAL   B HG23 1 
ATOM   3165  N  N    . GLU   A 1 204 ? 3.067   19.335  41.145  1.00 41.87  ?  203 GLU   B N    1 
ATOM   3166  C  CA   . GLU   A 1 204 ? 3.555   19.820  42.432  1.00 43.38  ?  203 GLU   B CA   1 
ATOM   3167  C  C    . GLU   A 1 204 ? 2.550   19.571  43.556  1.00 45.23  ?  203 GLU   B C    1 
ATOM   3168  O  O    . GLU   A 1 204 ? 2.917   19.551  44.731  1.00 43.45  ?  203 GLU   B O    1 
ATOM   3169  C  CB   . GLU   A 1 204 ? 3.874   21.314  42.348  1.00 49.22  ?  203 GLU   B CB   1 
ATOM   3170  C  CG   . GLU   A 1 204 ? 4.905   21.668  41.289  1.00 60.18  ?  203 GLU   B CG   1 
ATOM   3171  C  CD   . GLU   A 1 204 ? 4.289   22.320  40.067  1.00 68.24  ?  203 GLU   B CD   1 
ATOM   3172  O  OE1  . GLU   A 1 204 ? 4.402   23.556  39.930  1.00 67.16  ?  203 GLU   B OE1  1 
ATOM   3173  O  OE2  . GLU   A 1 204 ? 3.691   21.597  39.242  1.00 68.27  -1 203 GLU   B OE2  1 
ATOM   3174  H  H    . GLU   A 1 204 ? 2.796   19.961  40.622  1.00 50.24  ?  203 GLU   B H    1 
ATOM   3175  H  HA   . GLU   A 1 204 ? 4.383   19.345  42.656  1.00 52.05  ?  203 GLU   B HA   1 
ATOM   3176  H  HB2  . GLU   A 1 204 ? 3.057   21.796  42.141  1.00 59.07  ?  203 GLU   B HB2  1 
ATOM   3177  H  HB3  . GLU   A 1 204 ? 4.219   21.608  43.206  1.00 59.07  ?  203 GLU   B HB3  1 
ATOM   3178  H  HG2  . GLU   A 1 204 ? 5.549   22.287  41.667  1.00 72.22  ?  203 GLU   B HG2  1 
ATOM   3179  H  HG3  . GLU   A 1 204 ? 5.354   20.857  41.001  1.00 72.22  ?  203 GLU   B HG3  1 
ATOM   3180  N  N    . ALA   A 1 205 ? 1.286   19.380  43.192  1.00 43.23  ?  204 ALA   B N    1 
ATOM   3181  C  CA   . ALA   A 1 205 ? 0.231   19.130  44.170  1.00 40.56  ?  204 ALA   B CA   1 
ATOM   3182  C  C    . ALA   A 1 205 ? 0.092   17.646  44.518  1.00 43.18  ?  204 ALA   B C    1 
ATOM   3183  O  O    . ALA   A 1 205 ? -0.652  17.291  45.432  1.00 41.22  ?  204 ALA   B O    1 
ATOM   3184  C  CB   . ALA   A 1 205 ? -1.095  19.671  43.657  1.00 41.40  ?  204 ALA   B CB   1 
ATOM   3185  H  H    . ALA   A 1 205 ? 1.009   19.389  42.378  1.00 51.88  ?  204 ALA   B H    1 
ATOM   3186  H  HA   . ALA   A 1 205 ? 0.449   19.610  44.996  1.00 48.68  ?  204 ALA   B HA   1 
ATOM   3187  H  HB1  . ALA   A 1 205 ? -1.781  19.474  44.299  1.00 49.68  ?  204 ALA   B HB1  1 
ATOM   3188  H  HB2  . ALA   A 1 205 ? -1.019  20.620  43.540  1.00 49.68  ?  204 ALA   B HB2  1 
ATOM   3189  H  HB3  . ALA   A 1 205 ? -1.300  19.251  42.819  1.00 49.68  ?  204 ALA   B HB3  1 
ATOM   3190  N  N    . VAL   A 1 206 ? 0.795   16.781  43.792  1.00 34.98  ?  205 VAL   B N    1 
ATOM   3191  C  CA   . VAL   A 1 206 ? 0.729   15.348  44.048  1.00 29.65  ?  205 VAL   B CA   1 
ATOM   3192  C  C    . VAL   A 1 206 ? 2.117   14.768  44.305  1.00 37.91  ?  205 VAL   B C    1 
ATOM   3193  O  O    . VAL   A 1 206 ? 2.369   13.597  44.024  1.00 37.93  ?  205 VAL   B O    1 
ATOM   3194  C  CB   . VAL   A 1 206 ? 0.091   14.602  42.863  1.00 38.22  ?  205 VAL   B CB   1 
ATOM   3195  C  CG1  . VAL   A 1 206 ? -1.213  15.271  42.456  1.00 41.60  ?  205 VAL   B CG1  1 
ATOM   3196  C  CG2  . VAL   A 1 206 ? 1.056   14.550  41.689  1.00 34.86  ?  205 VAL   B CG2  1 
ATOM   3197  H  H    . VAL   A 1 206 ? 1.313   16.985  43.138  1.00 41.97  ?  205 VAL   B H    1 
ATOM   3198  H  HA   . VAL   A 1 206 ? 0.179   15.188  44.842  1.00 35.58  ?  205 VAL   B HA   1 
ATOM   3199  H  HB   . VAL   A 1 206 ? -0.109  13.682  43.134  1.00 45.87  ?  205 VAL   B HB   1 
ATOM   3200  H  HG11 . VAL   A 1 206 ? -1.659  14.717  41.812  1.00 49.92  ?  205 VAL   B HG11 1 
ATOM   3201  H  HG12 . VAL   A 1 206 ? -1.764  15.379  43.234  1.00 49.92  ?  205 VAL   B HG12 1 
ATOM   3202  H  HG13 . VAL   A 1 206 ? -1.016  16.128  42.072  1.00 49.92  ?  205 VAL   B HG13 1 
ATOM   3203  H  HG21 . VAL   A 1 206 ? 0.626   14.108  40.953  1.00 41.84  ?  205 VAL   B HG21 1 
ATOM   3204  H  HG22 . VAL   A 1 206 ? 1.292   15.447  41.440  1.00 41.84  ?  205 VAL   B HG22 1 
ATOM   3205  H  HG23 . VAL   A 1 206 ? 1.841   14.064  41.951  1.00 41.84  ?  205 VAL   B HG23 1 
ATOM   3206  N  N    . MET   A 1 207 ? 3.013   15.589  44.844  1.00 41.88  ?  206 MET   B N    1 
ATOM   3207  C  CA   . MET   A 1 207 ? 4.372   15.147  45.135  1.00 39.13  ?  206 MET   B CA   1 
ATOM   3208  C  C    . MET   A 1 207 ? 4.945   15.877  46.348  1.00 35.35  ?  206 MET   B C    1 
ATOM   3209  O  O    . MET   A 1 207 ? 4.539   16.998  46.658  1.00 32.31  ?  206 MET   B O    1 
ATOM   3210  C  CB   . MET   A 1 207 ? 5.276   15.383  43.923  1.00 33.03  ?  206 MET   B CB   1 
ATOM   3211  C  CG   . MET   A 1 207 ? 5.349   14.205  42.965  1.00 40.19  ?  206 MET   B CG   1 
ATOM   3212  S  SD   . MET   A 1 207 ? 6.593   14.430  41.679  1.00 47.69  ?  206 MET   B SD   1 
ATOM   3213  C  CE   . MET   A 1 207 ? 7.740   13.114  42.080  1.00 45.03  ?  206 MET   B CE   1 
ATOM   3214  H  H    . MET   A 1 207 ? 2.859   16.409  45.052  1.00 50.25  ?  206 MET   B H    1 
ATOM   3215  H  HA   . MET   A 1 207 ? 4.353   14.183  45.313  1.00 46.95  ?  206 MET   B HA   1 
ATOM   3216  H  HB2  . MET   A 1 207 ? 4.941   16.147  43.429  1.00 39.63  ?  206 MET   B HB2  1 
ATOM   3217  H  HB3  . MET   A 1 207 ? 6.177   15.564  44.237  1.00 39.63  ?  206 MET   B HB3  1 
ATOM   3218  H  HG2  . MET   A 1 207 ? 5.573   13.404  43.465  1.00 48.23  ?  206 MET   B HG2  1 
ATOM   3219  H  HG3  . MET   A 1 207 ? 4.488   14.097  42.532  1.00 48.23  ?  206 MET   B HG3  1 
ATOM   3220  H  HE1  . MET   A 1 207 ? 8.632   13.469  42.091  1.00 54.04  ?  206 MET   B HE1  1 
ATOM   3221  H  HE2  . MET   A 1 207 ? 7.517   12.760  42.944  1.00 54.04  ?  206 MET   B HE2  1 
ATOM   3222  H  HE3  . MET   A 1 207 ? 7.670   12.424  41.415  1.00 54.04  ?  206 MET   B HE3  1 
ATOM   3223  N  N    . TYR   A 1 208 ? 5.889   15.234  47.032  1.00 37.63  ?  207 TYR   B N    1 
ATOM   3224  C  CA   . TYR   A 1 208 ? 6.533   15.817  48.205  1.00 36.66  ?  207 TYR   B CA   1 
ATOM   3225  C  C    . TYR   A 1 208 ? 7.902   15.173  48.405  1.00 38.08  ?  207 TYR   B C    1 
ATOM   3226  O  O    . TYR   A 1 208 ? 8.125   14.035  47.990  1.00 30.37  ?  207 TYR   B O    1 
ATOM   3227  C  CB   . TYR   A 1 208 ? 5.672   15.622  49.457  1.00 35.15  ?  207 TYR   B CB   1 
ATOM   3228  C  CG   . TYR   A 1 208 ? 6.039   16.548  50.597  1.00 38.62  ?  207 TYR   B CG   1 
ATOM   3229  C  CD1  . TYR   A 1 208 ? 5.727   17.900  50.547  1.00 42.14  ?  207 TYR   B CD1  1 
ATOM   3230  C  CD2  . TYR   A 1 208 ? 6.703   16.070  51.718  1.00 42.30  ?  207 TYR   B CD2  1 
ATOM   3231  C  CE1  . TYR   A 1 208 ? 6.062   18.749  51.585  1.00 44.92  ?  207 TYR   B CE1  1 
ATOM   3232  C  CE2  . TYR   A 1 208 ? 7.043   16.912  52.760  1.00 40.63  ?  207 TYR   B CE2  1 
ATOM   3233  C  CZ   . TYR   A 1 208 ? 6.720   18.250  52.688  1.00 43.27  ?  207 TYR   B CZ   1 
ATOM   3234  O  OH   . TYR   A 1 208 ? 7.055   19.094  53.723  1.00 47.69  ?  207 TYR   B OH   1 
ATOM   3235  H  H    . TYR   A 1 208 ? 6.183   14.450  46.838  1.00 45.16  ?  207 TYR   B H    1 
ATOM   3236  H  HA   . TYR   A 1 208 ? 6.657   16.779  48.062  1.00 44.00  ?  207 TYR   B HA   1 
ATOM   3237  H  HB2  . TYR   A 1 208 ? 4.742   15.784  49.237  1.00 42.18  ?  207 TYR   B HB2  1 
ATOM   3238  H  HB3  . TYR   A 1 208 ? 5.779   14.711  49.771  1.00 42.18  ?  207 TYR   B HB3  1 
ATOM   3239  H  HD1  . TYR   A 1 208 ? 5.283   18.240  49.805  1.00 50.57  ?  207 TYR   B HD1  1 
ATOM   3240  H  HD2  . TYR   A 1 208 ? 6.923   15.168  51.770  1.00 50.76  ?  207 TYR   B HD2  1 
ATOM   3241  H  HE1  . TYR   A 1 208 ? 5.846   19.653  51.539  1.00 53.90  ?  207 TYR   B HE1  1 
ATOM   3242  H  HE2  . TYR   A 1 208 ? 7.487   16.577  53.506  1.00 48.76  ?  207 TYR   B HE2  1 
ATOM   3243  H  HH   . TYR   A 1 208 ? 7.702   18.798  54.130  1.00 57.23  ?  207 TYR   B HH   1 
ATOM   3244  N  N    . MET   A 1 209 ? 8.816   15.900  49.040  1.00 36.87  ?  208 MET   B N    1 
ATOM   3245  C  CA   . MET   A 1 209 ? 10.159  15.390  49.285  1.00 43.16  ?  208 MET   B CA   1 
ATOM   3246  C  C    . MET   A 1 209 ? 10.613  15.723  50.702  1.00 32.92  ?  208 MET   B C    1 
ATOM   3247  O  O    . MET   A 1 209 ? 11.292  16.725  50.926  1.00 43.38  ?  208 MET   B O    1 
ATOM   3248  C  CB   . MET   A 1 209 ? 11.142  15.982  48.274  1.00 34.21  ?  208 MET   B CB   1 
ATOM   3249  C  CG   . MET   A 1 209 ? 12.505  15.307  48.267  1.00 41.87  ?  208 MET   B CG   1 
ATOM   3250  S  SD   . MET   A 1 209 ? 12.403  13.525  48.520  1.00 43.09  ?  208 MET   B SD   1 
ATOM   3251  C  CE   . MET   A 1 209 ? 13.979  12.996  47.855  1.00 44.50  ?  208 MET   B CE   1 
ATOM   3252  H  H    . MET   A 1 209 ? 8.683   16.694  49.342  1.00 44.24  ?  208 MET   B H    1 
ATOM   3253  H  HA   . MET   A 1 209 ? 10.157  14.417  49.168  1.00 51.79  ?  208 MET   B HA   1 
ATOM   3254  H  HB2  . MET   A 1 209 ? 10.765  15.894  47.385  1.00 41.05  ?  208 MET   B HB2  1 
ATOM   3255  H  HB3  . MET   A 1 209 ? 11.276  16.920  48.482  1.00 41.05  ?  208 MET   B HB3  1 
ATOM   3256  H  HG2  . MET   A 1 209 ? 12.929  15.464  47.409  1.00 50.25  ?  208 MET   B HG2  1 
ATOM   3257  H  HG3  . MET   A 1 209 ? 13.048  15.681  48.979  1.00 50.25  ?  208 MET   B HG3  1 
ATOM   3258  H  HE1  . MET   A 1 209 ? 14.004  12.036  47.838  1.00 53.40  ?  208 MET   B HE1  1 
ATOM   3259  H  HE2  . MET   A 1 209 ? 14.075  13.343  46.964  1.00 53.40  ?  208 MET   B HE2  1 
ATOM   3260  H  HE3  . MET   A 1 209 ? 14.683  13.332  48.415  1.00 53.40  ?  208 MET   B HE3  1 
ATOM   3261  N  N    . GLY   A 1 210 ? 10.235  14.878  51.656  1.00 25.22  ?  209 GLY   B N    1 
ATOM   3262  C  CA   . GLY   A 1 210 ? 10.605  15.084  53.044  1.00 32.52  ?  209 GLY   B CA   1 
ATOM   3263  C  C    . GLY   A 1 210 ? 10.239  13.904  53.924  1.00 35.35  ?  209 GLY   B C    1 
ATOM   3264  O  O    . GLY   A 1 210 ? 11.113  13.173  54.390  1.00 33.46  ?  209 GLY   B O    1 
ATOM   3265  H  H    . GLY   A 1 210 ? 9.760   14.174  51.522  1.00 30.26  ?  209 GLY   B H    1 
ATOM   3266  H  HA2  . GLY   A 1 210 ? 11.562  15.228  53.105  1.00 39.03  ?  209 GLY   B HA2  1 
ATOM   3267  H  HA3  . GLY   A 1 210 ? 10.154  15.873  53.385  1.00 39.03  ?  209 GLY   B HA3  1 
ATOM   3268  N  N    . THR   A 1 211 ? 8.943   13.717  54.151  1.00 38.03  ?  210 THR   B N    1 
ATOM   3269  C  CA   . THR   A 1 211 ? 8.462   12.621  54.984  1.00 32.24  ?  210 THR   B CA   1 
ATOM   3270  C  C    . THR   A 1 211 ? 7.780   11.549  54.137  1.00 31.90  ?  210 THR   B C    1 
ATOM   3271  O  O    . THR   A 1 211 ? 7.279   11.833  53.049  1.00 29.64  ?  210 THR   B O    1 
ATOM   3272  C  CB   . THR   A 1 211 ? 7.468   13.124  56.046  1.00 37.07  ?  210 THR   B CB   1 
ATOM   3273  O  OG1  . THR   A 1 211 ? 6.907   12.009  56.749  1.00 35.51  ?  210 THR   B OG1  1 
ATOM   3274  C  CG2  . THR   A 1 211 ? 6.352   13.930  55.396  1.00 33.36  ?  210 THR   B CG2  1 
ATOM   3275  H  H    . THR   A 1 211 ? 8.318   14.215  53.832  1.00 45.63  ?  210 THR   B H    1 
ATOM   3276  H  HA   . THR   A 1 211 ? 9.226   12.217  55.446  1.00 38.68  ?  210 THR   B HA   1 
ATOM   3277  H  HB   . THR   A 1 211 ? 7.933   13.699  56.674  1.00 44.49  ?  210 THR   B HB   1 
ATOM   3278  H  HG1  . THR   A 1 211 ? 6.152   12.192  57.012  1.00 42.61  ?  210 THR   B HG1  1 
ATOM   3279  H  HG21 . THR   A 1 211 ? 6.081   14.644  55.978  1.00 40.03  ?  210 THR   B HG21 1 
ATOM   3280  H  HG22 . THR   A 1 211 ? 6.658   14.303  54.566  1.00 40.03  ?  210 THR   B HG22 1 
ATOM   3281  H  HG23 . THR   A 1 211 ? 5.595   13.365  55.223  1.00 40.03  ?  210 THR   B HG23 1 
ATOM   3282  N  N    . LEU   A 1 212 ? 7.765   10.317  54.639  1.00 30.70  ?  211 LEU   B N    1 
ATOM   3283  C  CA   . LEU   A 1 212 ? 7.145   9.208   53.921  1.00 33.82  ?  211 LEU   B CA   1 
ATOM   3284  C  C    . LEU   A 1 212 ? 5.730   8.894   54.413  1.00 36.48  ?  211 LEU   B C    1 
ATOM   3285  O  O    . LEU   A 1 212 ? 5.013   8.116   53.785  1.00 32.84  ?  211 LEU   B O    1 
ATOM   3286  C  CB   . LEU   A 1 212 ? 8.017   7.955   54.038  1.00 33.54  ?  211 LEU   B CB   1 
ATOM   3287  C  CG   . LEU   A 1 212 ? 9.391   8.035   53.370  1.00 33.21  ?  211 LEU   B CG   1 
ATOM   3288  C  CD1  . LEU   A 1 212 ? 10.306  6.950   53.918  1.00 29.94  ?  211 LEU   B CD1  1 
ATOM   3289  C  CD2  . LEU   A 1 212 ? 9.258   7.918   51.860  1.00 35.87  ?  211 LEU   B CD2  1 
ATOM   3290  H  H    . LEU   A 1 212 ? 8.120   10.091  55.389  1.00 36.84  ?  211 LEU   B H    1 
ATOM   3291  H  HA   . LEU   A 1 212 ? 7.086   9.442   52.971  1.00 40.59  ?  211 LEU   B HA   1 
ATOM   3292  H  HB2  . LEU   A 1 212 ? 8.162   7.771   54.980  1.00 40.25  ?  211 LEU   B HB2  1 
ATOM   3293  H  HB3  . LEU   A 1 212 ? 7.541   7.214   53.634  1.00 40.25  ?  211 LEU   B HB3  1 
ATOM   3294  H  HG   . LEU   A 1 212 ? 9.792   8.895   53.570  1.00 39.85  ?  211 LEU   B HG   1 
ATOM   3295  H  HD11 . LEU   A 1 212 ? 11.057  6.847   53.329  1.00 35.93  ?  211 LEU   B HD11 1 
ATOM   3296  H  HD12 . LEU   A 1 212 ? 10.607  7.207   54.793  1.00 35.93  ?  211 LEU   B HD12 1 
ATOM   3297  H  HD13 . LEU   A 1 212 ? 9.814   6.126   53.970  1.00 35.93  ?  211 LEU   B HD13 1 
ATOM   3298  H  HD21 . LEU   A 1 212 ? 9.558   7.047   51.588  1.00 43.04  ?  211 LEU   B HD21 1 
ATOM   3299  H  HD22 . LEU   A 1 212 ? 8.337   8.038   51.618  1.00 43.04  ?  211 LEU   B HD22 1 
ATOM   3300  H  HD23 . LEU   A 1 212 ? 9.797   8.595   51.444  1.00 43.04  ?  211 LEU   B HD23 1 
ATOM   3301  N  N    . SER   A 1 213 ? 5.328   9.495   55.530  1.00 35.40  ?  212 SER   B N    1 
ATOM   3302  C  CA   . SER   A 1 213 ? 4.000   9.256   56.085  1.00 35.08  ?  212 SER   B CA   1 
ATOM   3303  C  C    . SER   A 1 213 ? 3.005   10.320  55.611  1.00 33.51  ?  212 SER   B C    1 
ATOM   3304  O  O    . SER   A 1 213 ? 3.382   11.473  55.398  1.00 33.11  ?  212 SER   B O    1 
ATOM   3305  C  CB   . SER   A 1 213 ? 4.058   9.242   57.614  1.00 34.87  ?  212 SER   B CB   1 
ATOM   3306  O  OG   . SER   A 1 213 ? 2.792   9.543   58.176  1.00 47.48  ?  212 SER   B OG   1 
ATOM   3307  H  H    . SER   A 1 213 ? 5.798   10.049  55.987  1.00 42.48  ?  212 SER   B H    1 
ATOM   3308  H  HA   . SER   A 1 213 ? 3.701   8.371   55.796  1.00 42.10  ?  212 SER   B HA   1 
ATOM   3309  H  HB2  . SER   A 1 213 ? 4.329   8.358   57.909  1.00 41.85  ?  212 SER   B HB2  1 
ATOM   3310  H  HB3  . SER   A 1 213 ? 4.703   9.902   57.914  1.00 41.85  ?  212 SER   B HB3  1 
ATOM   3311  H  HG   . SER   A 1 213 ? 2.276   8.917   58.055  1.00 56.98  ?  212 SER   B HG   1 
ATOM   3312  N  N    . TYR   A 1 214 ? 1.740   9.937   55.446  1.00 36.59  ?  213 TYR   B N    1 
ATOM   3313  C  CA   . TYR   A 1 214 ? 0.709   10.872  55.007  1.00 36.86  ?  213 TYR   B CA   1 
ATOM   3314  C  C    . TYR   A 1 214 ? 0.054   11.566  56.197  1.00 38.56  ?  213 TYR   B C    1 
ATOM   3315  O  O    . TYR   A 1 214 ? -0.293  12.745  56.123  1.00 36.87  ?  213 TYR   B O    1 
ATOM   3316  C  CB   . TYR   A 1 214 ? -0.357  10.149  54.181  1.00 30.23  ?  213 TYR   B CB   1 
ATOM   3317  C  CG   . TYR   A 1 214 ? -1.194  11.074  53.326  1.00 33.88  ?  213 TYR   B CG   1 
ATOM   3318  C  CD1  . TYR   A 1 214 ? -0.809  12.391  53.111  1.00 30.05  ?  213 TYR   B CD1  1 
ATOM   3319  C  CD2  . TYR   A 1 214 ? -2.370  10.632  52.734  1.00 36.93  ?  213 TYR   B CD2  1 
ATOM   3320  C  CE1  . TYR   A 1 214 ? -1.569  13.241  52.330  1.00 43.89  ?  213 TYR   B CE1  1 
ATOM   3321  C  CE2  . TYR   A 1 214 ? -3.138  11.474  51.953  1.00 38.69  ?  213 TYR   B CE2  1 
ATOM   3322  C  CZ   . TYR   A 1 214 ? -2.733  12.778  51.754  1.00 42.83  ?  213 TYR   B CZ   1 
ATOM   3323  O  OH   . TYR   A 1 214 ? -3.493  13.622  50.977  1.00 40.46  ?  213 TYR   B OH   1 
ATOM   3324  H  H    . TYR   A 1 214 ? 1.444   9.139   55.573  1.00 43.90  ?  213 TYR   B H    1 
ATOM   3325  H  HA   . TYR   A 1 214 ? 1.119   11.558  54.440  1.00 44.23  ?  213 TYR   B HA   1 
ATOM   3326  H  HB2  . TYR   A 1 214 ? 0.082   9.517   53.590  1.00 36.28  ?  213 TYR   B HB2  1 
ATOM   3327  H  HB3  . TYR   A 1 214 ? -0.954  9.678   54.783  1.00 36.28  ?  213 TYR   B HB3  1 
ATOM   3328  H  HD1  . TYR   A 1 214 ? -0.024  12.706  53.498  1.00 36.06  ?  213 TYR   B HD1  1 
ATOM   3329  H  HD2  . TYR   A 1 214 ? -2.645  9.754   52.866  1.00 44.32  ?  213 TYR   B HD2  1 
ATOM   3330  H  HE1  . TYR   A 1 214 ? -1.298  14.120  52.196  1.00 52.67  ?  213 TYR   B HE1  1 
ATOM   3331  H  HE2  . TYR   A 1 214 ? -3.923  11.164  51.563  1.00 46.43  ?  213 TYR   B HE2  1 
ATOM   3332  H  HH   . TYR   A 1 214 ? -4.027  13.189  50.531  1.00 48.55  ?  213 TYR   B HH   1 
ATOM   3333  N  N    . GLU   A 1 215 ? -0.115  10.831  57.293  1.00 36.21  ?  214 GLU   B N    1 
ATOM   3334  C  CA   . GLU   A 1 215 ? -0.722  11.381  58.500  1.00 42.09  ?  214 GLU   B CA   1 
ATOM   3335  C  C    . GLU   A 1 215 ? 0.151   12.488  59.077  1.00 46.98  ?  214 GLU   B C    1 
ATOM   3336  O  O    . GLU   A 1 215 ? -0.352  13.507  59.549  1.00 44.10  ?  214 GLU   B O    1 
ATOM   3337  C  CB   . GLU   A 1 215 ? -0.925  10.281  59.542  1.00 43.91  ?  214 GLU   B CB   1 
ATOM   3338  C  CG   . GLU   A 1 215 ? -1.842  9.159   59.084  1.00 54.96  ?  214 GLU   B CG   1 
ATOM   3339  C  CD   . GLU   A 1 215 ? -3.112  9.674   58.438  1.00 66.70  ?  214 GLU   B CD   1 
ATOM   3340  O  OE1  . GLU   A 1 215 ? -3.944  10.273  59.151  1.00 58.58  ?  214 GLU   B OE1  1 
ATOM   3341  O  OE2  . GLU   A 1 215 ? -3.279  9.480   57.215  1.00 54.50  -1 214 GLU   B OE2  1 
ATOM   3342  H  H    . GLU   A 1 215 ? 0.110   10.006  57.367  1.00 43.45  ?  214 GLU   B H    1 
ATOM   3343  H  HA   . GLU   A 1 215 ? -1.598  11.763  58.278  1.00 50.51  ?  214 GLU   B HA   1 
ATOM   3344  H  HB2  . GLU   A 1 215 ? -0.063  9.890   59.754  1.00 52.69  ?  214 GLU   B HB2  1 
ATOM   3345  H  HB3  . GLU   A 1 215 ? -1.312  10.673  60.340  1.00 52.69  ?  214 GLU   B HB3  1 
ATOM   3346  H  HG2  . GLU   A 1 215 ? -1.372  8.615   58.432  1.00 65.95  ?  214 GLU   B HG2  1 
ATOM   3347  H  HG3  . GLU   A 1 215 ? -2.090  8.619   59.851  1.00 65.95  ?  214 GLU   B HG3  1 
ATOM   3348  N  N    . GLN   A 1 216 ? 1.464   12.282  59.033  1.00 45.95  ?  215 GLN   B N    1 
ATOM   3349  C  CA   . GLN   A 1 216 ? 2.413   13.265  59.537  1.00 44.05  ?  215 GLN   B CA   1 
ATOM   3350  C  C    . GLN   A 1 216 ? 2.258   14.580  58.779  1.00 41.07  ?  215 GLN   B C    1 
ATOM   3351  O  O    . GLN   A 1 216 ? 2.248   15.655  59.378  1.00 47.88  ?  215 GLN   B O    1 
ATOM   3352  C  CB   . GLN   A 1 216 ? 3.844   12.743  59.397  1.00 52.82  ?  215 GLN   B CB   1 
ATOM   3353  C  CG   . GLN   A 1 216 ? 4.869   13.523  60.204  1.00 51.17  ?  215 GLN   B CG   1 
ATOM   3354  C  CD   . GLN   A 1 216 ? 4.689   13.345  61.699  1.00 74.94  ?  215 GLN   B CD   1 
ATOM   3355  O  OE1  . GLN   A 1 216 ? 5.021   12.299  62.255  1.00 76.76  ?  215 GLN   B OE1  1 
ATOM   3356  N  NE2  . GLN   A 1 216 ? 4.162   14.370  62.358  1.00 65.15  ?  215 GLN   B NE2  1 
ATOM   3357  H  H    . GLN   A 1 216 ? 1.833   11.573  58.714  1.00 55.14  ?  215 GLN   B H    1 
ATOM   3358  H  HA   . GLN   A 1 216 ? 2.236   13.432  60.487  1.00 52.86  ?  215 GLN   B HA   1 
ATOM   3359  H  HB2  . GLN   A 1 216 ? 3.869   11.822  59.701  1.00 63.38  ?  215 GLN   B HB2  1 
ATOM   3360  H  HB3  . GLN   A 1 216 ? 4.103   12.788  58.463  1.00 63.38  ?  215 GLN   B HB3  1 
ATOM   3361  H  HG2  . GLN   A 1 216 ? 5.758   13.215  59.970  1.00 61.41  ?  215 GLN   B HG2  1 
ATOM   3362  H  HG3  . GLN   A 1 216 ? 4.780   14.468  60.001  1.00 61.41  ?  215 GLN   B HG3  1 
ATOM   3363  H  HE21 . GLN   A 1 216 ? 4.091   15.137  61.975  1.00 78.18  ?  215 GLN   B HE21 1 
ATOM   3364  H  HE22 . GLN   A 1 216 ? 3.890   14.266  63.167  1.00 78.18  ?  215 GLN   B HE22 1 
ATOM   3365  N  N    . PHE   A 1 217 ? 2.134   14.484  57.458  1.00 42.12  ?  216 PHE   B N    1 
ATOM   3366  C  CA   . PHE   A 1 217 ? 1.965   15.659  56.613  1.00 38.75  ?  216 PHE   B CA   1 
ATOM   3367  C  C    . PHE   A 1 217 ? 0.721   16.436  57.032  1.00 41.33  ?  216 PHE   B C    1 
ATOM   3368  O  O    . PHE   A 1 217 ? 0.752   17.660  57.154  1.00 39.91  ?  216 PHE   B O    1 
ATOM   3369  C  CB   . PHE   A 1 217 ? 1.854   15.244  55.145  1.00 35.24  ?  216 PHE   B CB   1 
ATOM   3370  C  CG   . PHE   A 1 217 ? 2.164   16.350  54.177  1.00 38.63  ?  216 PHE   B CG   1 
ATOM   3371  C  CD1  . PHE   A 1 217 ? 3.062   17.350  54.512  1.00 42.38  ?  216 PHE   B CD1  1 
ATOM   3372  C  CD2  . PHE   A 1 217 ? 1.558   16.388  52.932  1.00 42.86  ?  216 PHE   B CD2  1 
ATOM   3373  C  CE1  . PHE   A 1 217 ? 3.350   18.368  53.623  1.00 48.00  ?  216 PHE   B CE1  1 
ATOM   3374  C  CE2  . PHE   A 1 217 ? 1.842   17.403  52.039  1.00 46.04  ?  216 PHE   B CE2  1 
ATOM   3375  C  CZ   . PHE   A 1 217 ? 2.739   18.395  52.385  1.00 37.34  ?  216 PHE   B CZ   1 
ATOM   3376  H  H    . PHE   A 1 217 ? 2.146   13.742  57.024  1.00 50.54  ?  216 PHE   B H    1 
ATOM   3377  H  HA   . PHE   A 1 217 ? 2.744   16.246  56.711  1.00 46.50  ?  216 PHE   B HA   1 
ATOM   3378  H  HB2  . PHE   A 1 217 ? 2.479   14.521  54.978  1.00 42.29  ?  216 PHE   B HB2  1 
ATOM   3379  H  HB3  . PHE   A 1 217 ? 0.949   14.943  54.969  1.00 42.29  ?  216 PHE   B HB3  1 
ATOM   3380  H  HD1  . PHE   A 1 217 ? 3.476   17.336  55.345  1.00 50.85  ?  216 PHE   B HD1  1 
ATOM   3381  H  HD2  . PHE   A 1 217 ? 0.954   15.723  52.695  1.00 51.43  ?  216 PHE   B HD2  1 
ATOM   3382  H  HE1  . PHE   A 1 217 ? 3.954   19.034  53.859  1.00 57.60  ?  216 PHE   B HE1  1 
ATOM   3383  H  HE2  . PHE   A 1 217 ? 1.429   17.419  51.205  1.00 55.25  ?  216 PHE   B HE2  1 
ATOM   3384  H  HZ   . PHE   A 1 217 ? 2.931   19.079  51.785  1.00 44.81  ?  216 PHE   B HZ   1 
ATOM   3385  N  N    . LYS   A 1 218 ? -0.375  15.715  57.252  1.00 38.34  ?  217 LYS   B N    1 
ATOM   3386  C  CA   . LYS   A 1 218 ? -1.628  16.333  57.665  1.00 51.74  ?  217 LYS   B CA   1 
ATOM   3387  C  C    . LYS   A 1 218 ? -1.464  16.958  59.045  1.00 51.90  ?  217 LYS   B C    1 
ATOM   3388  O  O    . LYS   A 1 218 ? -1.852  18.105  59.268  1.00 48.93  ?  217 LYS   B O    1 
ATOM   3389  C  CB   . LYS   A 1 218 ? -2.752  15.296  57.687  1.00 40.16  ?  217 LYS   B CB   1 
ATOM   3390  C  CG   . LYS   A 1 218 ? -3.102  14.730  56.320  1.00 43.69  ?  217 LYS   B CG   1 
ATOM   3391  C  CD   . LYS   A 1 218 ? -3.861  13.418  56.439  1.00 40.35  ?  217 LYS   B CD   1 
ATOM   3392  C  CE   . LYS   A 1 218 ? -4.487  13.015  55.114  1.00 46.92  ?  217 LYS   B CE   1 
ATOM   3393  N  NZ   . LYS   A 1 218 ? -5.231  11.729  55.208  1.00 58.81  ?  217 LYS   B NZ   1 
ATOM   3394  H  H    . LYS   A 1 218 ? -0.417  14.860  57.169  1.00 46.01  ?  217 LYS   B H    1 
ATOM   3395  H  HA   . LYS   A 1 218 ? -1.869  17.039  57.030  1.00 62.08  ?  217 LYS   B HA   1 
ATOM   3396  H  HB2  . LYS   A 1 218 ? -2.479  14.555  58.251  1.00 48.19  ?  217 LYS   B HB2  1 
ATOM   3397  H  HB3  . LYS   A 1 218 ? -3.551  15.709  58.051  1.00 48.19  ?  217 LYS   B HB3  1 
ATOM   3398  H  HG2  . LYS   A 1 218 ? -3.662  15.363  55.844  1.00 52.43  ?  217 LYS   B HG2  1 
ATOM   3399  H  HG3  . LYS   A 1 218 ? -2.286  14.565  55.823  1.00 52.43  ?  217 LYS   B HG3  1 
ATOM   3400  H  HD2  . LYS   A 1 218 ? -3.248  12.717  56.712  1.00 48.42  ?  217 LYS   B HD2  1 
ATOM   3401  H  HD3  . LYS   A 1 218 ? -4.570  13.517  57.094  1.00 48.42  ?  217 LYS   B HD3  1 
ATOM   3402  H  HE2  . LYS   A 1 218 ? -5.110  13.704  54.834  1.00 56.30  ?  217 LYS   B HE2  1 
ATOM   3403  H  HE3  . LYS   A 1 218 ? -3.787  12.910  54.452  1.00 56.30  ?  217 LYS   B HE3  1 
ATOM   3404  H  HZ1  . LYS   A 1 218 ? -5.485  11.433  54.331  1.00 70.57  ?  217 LYS   B HZ1  1 
ATOM   3405  H  HZ2  . LYS   A 1 218 ? -4.678  11.059  55.616  1.00 70.57  ?  217 LYS   B HZ2  1 
ATOM   3406  H  HZ3  . LYS   A 1 218 ? -6.024  11.845  55.739  1.00 70.57  ?  217 LYS   B HZ3  1 
ATOM   3407  N  N    . LYS   A 1 219 ? -0.884  16.196  59.968  1.00 50.55  ?  218 LYS   B N    1 
ATOM   3408  C  CA   . LYS   A 1 219 ? -0.658  16.678  61.324  1.00 50.44  ?  218 LYS   B CA   1 
ATOM   3409  C  C    . LYS   A 1 219 ? 0.263   17.890  61.291  1.00 53.31  ?  218 LYS   B C    1 
ATOM   3410  O  O    . LYS   A 1 219 ? -0.062  18.945  61.837  1.00 50.75  ?  218 LYS   B O    1 
ATOM   3411  C  CB   . LYS   A 1 219 ? -0.043  15.577  62.187  1.00 42.04  ?  218 LYS   B CB   1 
ATOM   3412  C  CG   . LYS   A 1 219 ? -1.061  14.637  62.811  1.00 52.74  ?  218 LYS   B CG   1 
ATOM   3413  C  CD   . LYS   A 1 219 ? -0.424  13.316  63.210  1.00 64.22  ?  218 LYS   B CD   1 
ATOM   3414  C  CE   . LYS   A 1 219 ? -1.468  12.224  63.376  1.00 63.88  ?  218 LYS   B CE   1 
ATOM   3415  N  NZ   . LYS   A 1 219 ? -0.999  11.137  64.279  1.00 77.65  ?  218 LYS   B NZ   1 
ATOM   3416  H  H    . LYS   A 1 219 ? -0.612  15.392  59.831  1.00 60.66  ?  218 LYS   B H    1 
ATOM   3417  H  HA   . LYS   A 1 219 ? -1.512  16.946  61.724  1.00 60.52  ?  218 LYS   B HA   1 
ATOM   3418  H  HB2  . LYS   A 1 219 ? 0.552   15.044  61.636  1.00 50.45  ?  218 LYS   B HB2  1 
ATOM   3419  H  HB3  . LYS   A 1 219 ? 0.459   15.988  62.908  1.00 50.45  ?  218 LYS   B HB3  1 
ATOM   3420  H  HG2  . LYS   A 1 219 ? -1.432  15.049  63.607  1.00 63.28  ?  218 LYS   B HG2  1 
ATOM   3421  H  HG3  . LYS   A 1 219 ? -1.764  14.454  62.168  1.00 63.28  ?  218 LYS   B HG3  1 
ATOM   3422  H  HD2  . LYS   A 1 219 ? 0.199   13.040  62.519  1.00 77.07  ?  218 LYS   B HD2  1 
ATOM   3423  H  HD3  . LYS   A 1 219 ? 0.040   13.426  64.055  1.00 77.07  ?  218 LYS   B HD3  1 
ATOM   3424  H  HE2  . LYS   A 1 219 ? -2.273  12.607  63.757  1.00 76.65  ?  218 LYS   B HE2  1 
ATOM   3425  H  HE3  . LYS   A 1 219 ? -1.662  11.835  62.509  1.00 76.65  ?  218 LYS   B HE3  1 
ATOM   3426  H  HZ1  . LYS   A 1 219 ? -1.747  10.613  64.578  1.00 93.17  ?  218 LYS   B HZ1  1 
ATOM   3427  H  HZ2  . LYS   A 1 219 ? -0.384  10.565  63.813  1.00 93.17  ?  218 LYS   B HZ2  1 
ATOM   3428  H  HZ3  . LYS   A 1 219 ? -0.557  11.513  65.043  1.00 93.17  ?  218 LYS   B HZ3  1 
ATOM   3429  N  N    . GLY   A 1 220 ? 1.415   17.732  60.647  1.00 58.19  ?  219 GLY   B N    1 
ATOM   3430  C  CA   . GLY   A 1 220 ? 2.376   18.812  60.533  1.00 51.44  ?  219 GLY   B CA   1 
ATOM   3431  C  C    . GLY   A 1 220 ? 3.816   18.336  60.617  1.00 50.94  ?  219 GLY   B C    1 
ATOM   3432  O  O    . GLY   A 1 220 ? 4.098   17.272  61.168  1.00 48.12  ?  219 GLY   B O    1 
ATOM   3433  H  H    . GLY   A 1 220 ? 1.661   17.001  60.266  1.00 69.83  ?  219 GLY   B H    1 
ATOM   3434  H  HA2  . GLY   A 1 220 ? 2.238   19.260  59.684  1.00 61.73  ?  219 GLY   B HA2  1 
ATOM   3435  H  HA3  . GLY   A 1 220 ? 2.225   19.453  61.246  1.00 61.73  ?  219 GLY   B HA3  1 
ATOM   3436  N  N    . VAL   A 1 221 ? 4.730   19.132  60.068  1.00 53.95  ?  220 VAL   B N    1 
ATOM   3437  C  CA   . VAL   A 1 221 ? 6.150   18.808  60.078  1.00 59.83  ?  220 VAL   B CA   1 
ATOM   3438  C  C    . VAL   A 1 221 ? 6.956   20.090  60.259  1.00 65.01  ?  220 VAL   B C    1 
ATOM   3439  O  O    . VAL   A 1 221 ? 6.522   21.161  59.839  1.00 60.58  ?  220 VAL   B O    1 
ATOM   3440  C  CB   . VAL   A 1 221 ? 6.586   18.142  58.762  1.00 60.95  ?  220 VAL   B CB   1 
ATOM   3441  C  CG1  . VAL   A 1 221 ? 6.109   16.699  58.710  1.00 60.31  ?  220 VAL   B CG1  1 
ATOM   3442  C  CG2  . VAL   A 1 221 ? 6.064   18.933  57.572  1.00 52.29  ?  220 VAL   B CG2  1 
ATOM   3443  H  H    . VAL   A 1 221 ? 4.554   19.876  59.678  1.00 64.75  ?  220 VAL   B H    1 
ATOM   3444  H  HA   . VAL   A 1 221 ? 6.340   18.195  60.818  1.00 71.79  ?  220 VAL   B HA   1 
ATOM   3445  H  HB   . VAL   A 1 221 ? 7.565   18.139  58.716  1.00 73.14  ?  220 VAL   B HB   1 
ATOM   3446  H  HG11 . VAL   A 1 221 ? 6.547   16.252  57.983  1.00 72.37  ?  220 VAL   B HG11 1 
ATOM   3447  H  HG12 . VAL   A 1 221 ? 6.329   16.268  59.539  1.00 72.37  ?  220 VAL   B HG12 1 
ATOM   3448  H  HG13 . VAL   A 1 221 ? 5.158   16.687  58.579  1.00 72.37  ?  220 VAL   B HG13 1 
ATOM   3449  H  HG21 . VAL   A 1 221 ? 6.372   18.521  56.762  1.00 62.75  ?  220 VAL   B HG21 1 
ATOM   3450  H  HG22 . VAL   A 1 221 ? 5.104   18.935  57.595  1.00 62.75  ?  220 VAL   B HG22 1 
ATOM   3451  H  HG23 . VAL   A 1 221 ? 6.394   19.833  57.628  1.00 62.75  ?  220 VAL   B HG23 1 
ATOM   3452  N  N    . GLN   A 1 222 ? 8.139   20.007  60.835  1.00 74.93  ?  221 GLN   B N    1 
ATOM   3453  C  CA   . GLN   A 1 222 ? 8.880   21.223  61.073  1.00 76.65  ?  221 GLN   B CA   1 
ATOM   3454  C  C    . GLN   A 1 222 ? 9.857   21.590  59.958  1.00 76.48  ?  221 GLN   B C    1 
ATOM   3455  O  O    . GLN   A 1 222 ? 10.612  20.752  59.514  1.00 72.62  ?  221 GLN   B O    1 
ATOM   3456  C  CB   . GLN   A 1 222 ? 9.578   21.125  62.398  1.00 75.73  ?  221 GLN   B CB   1 
ATOM   3457  C  CG   . GLN   A 1 222 ? 8.803   21.809  63.509  1.00 87.36  ?  221 GLN   B CG   1 
ATOM   3458  C  CD   . GLN   A 1 222 ? 7.341   21.426  63.538  1.00 84.05  ?  221 GLN   B CD   1 
ATOM   3459  O  OE1  . GLN   A 1 222 ? 6.467   22.282  63.455  1.00 112.90 ?  221 GLN   B OE1  1 
ATOM   3460  N  NE2  . GLN   A 1 222 ? 7.067   20.140  63.681  1.00 76.18  ?  221 GLN   B NE2  1 
ATOM   3461  H  H    . GLN   A 1 222 ? 8.525   19.282  61.090  1.00 89.92  ?  221 GLN   B H    1 
ATOM   3462  H  HA   . GLN   A 1 222 ? 8.198   21.917  61.183  1.00 91.98  ?  221 GLN   B HA   1 
ATOM   3463  H  HB2  . GLN   A 1 222 ? 9.682   20.190  62.634  1.00 90.87  ?  221 GLN   B HB2  1 
ATOM   3464  H  HB3  . GLN   A 1 222 ? 10.447  21.551  62.332  1.00 90.87  ?  221 GLN   B HB3  1 
ATOM   3465  H  HG2  . GLN   A 1 222 ? 9.193   21.562  64.362  1.00 104.84 ?  221 GLN   B HG2  1 
ATOM   3466  H  HG3  . GLN   A 1 222 ? 8.859   22.769  63.387  1.00 104.84 ?  221 GLN   B HG3  1 
ATOM   3467  H  HE21 . GLN   A 1 222 ? 7.704   19.576  63.809  1.00 91.42  ?  221 GLN   B HE21 1 
ATOM   3468  H  HE22 . GLN   A 1 222 ? 6.252   19.867  63.646  1.00 91.42  ?  221 GLN   B HE22 1 
ATOM   3469  N  N    . ILE   A 1 223 ? 9.834   22.839  59.504  1.00 76.74  ?  222 ILE   B N    1 
ATOM   3470  C  CA   . ILE   A 1 223 ? 10.682  23.301  58.440  1.00 74.95  ?  222 ILE   B CA   1 
ATOM   3471  C  C    . ILE   A 1 223 ? 11.114  24.731  58.747  1.00 87.25  ?  222 ILE   B C    1 
ATOM   3472  O  O    . ILE   A 1 223 ? 10.420  25.449  59.438  1.00 98.36  ?  222 ILE   B O    1 
ATOM   3473  C  CB   . ILE   A 1 223 ? 9.913   23.346  57.115  1.00 74.55  ?  222 ILE   B CB   1 
ATOM   3474  C  CG1  . ILE   A 1 223 ? 8.605   24.077  57.289  1.00 73.92  ?  222 ILE   B CG1  1 
ATOM   3475  C  CG2  . ILE   A 1 223 ? 9.588   21.970  56.599  1.00 70.55  ?  222 ILE   B CG2  1 
ATOM   3476  C  CD1  . ILE   A 1 223 ? 8.135   24.707  56.012  1.00 64.37  ?  222 ILE   B CD1  1 
ATOM   3477  H  H    . ILE   A 1 223 ? 9.341   23.481  59.796  1.00 92.08  ?  222 ILE   B H    1 
ATOM   3478  H  HA   . ILE   A 1 223 ? 11.472  22.728  58.348  1.00 89.93  ?  222 ILE   B HA   1 
ATOM   3479  H  HB   . ILE   A 1 223 ? 10.450  23.812  56.455  1.00 89.46  ?  222 ILE   B HB   1 
ATOM   3480  H  HG12 . ILE   A 1 223 ? 7.927   23.450  57.585  1.00 88.70  ?  222 ILE   B HG12 1 
ATOM   3481  H  HG13 . ILE   A 1 223 ? 8.719   24.780  57.948  1.00 88.70  ?  222 ILE   B HG13 1 
ATOM   3482  H  HG21 . ILE   A 1 223 ? 9.501   22.008  55.644  1.00 84.66  ?  222 ILE   B HG21 1 
ATOM   3483  H  HG22 . ILE   A 1 223 ? 10.299  21.370  56.839  1.00 84.66  ?  222 ILE   B HG22 1 
ATOM   3484  H  HG23 . ILE   A 1 223 ? 8.764   21.675  56.992  1.00 84.66  ?  222 ILE   B HG23 1 
ATOM   3485  H  HD11 . ILE   A 1 223 ? 7.185   24.835  56.058  1.00 77.25  ?  222 ILE   B HD11 1 
ATOM   3486  H  HD12 . ILE   A 1 223 ? 8.575   25.553  55.901  1.00 77.25  ?  222 ILE   B HD12 1 
ATOM   3487  H  HD13 . ILE   A 1 223 ? 8.352   24.126  55.279  1.00 77.25  ?  222 ILE   B HD13 1 
ATOM   3488  N  N    . PRO   A 1 224 ? 12.254  25.150  58.223  1.00 87.11  ?  223 PRO   B N    1 
ATOM   3489  C  CA   . PRO   A 1 224 ? 12.838  26.477  58.381  1.00 94.01  ?  223 PRO   B CA   1 
ATOM   3490  C  C    . PRO   A 1 224 ? 11.836  27.601  58.253  1.00 100.11 ?  223 PRO   B C    1 
ATOM   3491  O  O    . PRO   A 1 224 ? 11.724  28.164  57.169  1.00 83.44  ?  223 PRO   B O    1 
ATOM   3492  C  CB   . PRO   A 1 224 ? 13.813  26.554  57.221  1.00 90.62  ?  223 PRO   B CB   1 
ATOM   3493  C  CG   . PRO   A 1 224 ? 14.179  25.138  56.941  1.00 86.13  ?  223 PRO   B CG   1 
ATOM   3494  C  CD   . PRO   A 1 224 ? 13.182  24.225  57.574  1.00 82.22  ?  223 PRO   B CD   1 
ATOM   3495  H  HA   . PRO   A 1 224 ? 13.321  26.551  59.230  1.00 112.81 ?  223 PRO   B HA   1 
ATOM   3496  N  N    . THR   A 1 226 ? 13.290  31.172  56.629  1.00 127.71 ?  225 THR   B N    1 
ATOM   3497  C  CA   . THR   A 1 226 ? 14.013  32.359  57.125  1.00 115.79 ?  225 THR   B CA   1 
ATOM   3498  C  C    . THR   A 1 226 ? 13.194  32.974  58.238  1.00 124.08 ?  225 THR   B C    1 
ATOM   3499  O  O    . THR   A 1 226 ? 13.730  33.619  59.134  1.00 160.67 ?  225 THR   B O    1 
ATOM   3500  C  CB   . THR   A 1 226 ? 14.238  33.495  56.101  1.00 94.81  ?  225 THR   B CB   1 
ATOM   3501  O  OG1  . THR   A 1 226 ? 13.261  33.452  55.059  1.00 98.69  ?  225 THR   B OG1  1 
ATOM   3502  C  CG2  . THR   A 1 226 ? 15.637  33.438  55.526  1.00 79.01  ?  225 THR   B CG2  1 
ATOM   3503  N  N    . CYS   A 1 227 ? 11.880  32.816  58.136  1.00 125.12 ?  226 CYS   B N    1 
ATOM   3504  C  CA   . CYS   A 1 227 ? 10.950  33.325  59.141  1.00 130.61 ?  226 CYS   B CA   1 
ATOM   3505  C  C    . CYS   A 1 227 ? 11.091  32.644  60.520  1.00 140.64 ?  226 CYS   B C    1 
ATOM   3506  O  O    . CYS   A 1 227 ? 10.731  31.477  60.674  1.00 183.97 ?  226 CYS   B O    1 
ATOM   3507  C  CB   . CYS   A 1 227 ? 9.514   33.140  58.647  1.00 124.33 ?  226 CYS   B CB   1 
ATOM   3508  S  SG   . CYS   A 1 227 ? 8.282   34.079  59.580  1.00 137.80 ?  226 CYS   B SG   1 
ATOM   3509  H  H    . CYS   A 1 227 ? 11.490  32.405  57.489  1.00 150.15 ?  226 CYS   B H    1 
ATOM   3510  H  HA   . CYS   A 1 227 ? 11.085  34.292  59.206  1.00 156.73 ?  226 CYS   B HA   1 
ATOM   3511  H  HB2  . CYS   A 1 227 ? 9.464   33.426  57.722  1.00 149.20 ?  226 CYS   B HB2  1 
ATOM   3512  H  HB3  . CYS   A 1 227 ? 9.281   32.201  58.712  1.00 149.20 ?  226 CYS   B HB3  1 
ATOM   3513  H  HG   . CYS   A 1 227 ? 8.589   35.382  59.522  1.00 165.36 ?  226 CYS   B HG   1 
ATOM   3514  N  N    . GLY   A 1 228 ? 11.611  33.369  61.512  1.00 149.67 ?  227 GLY   B N    1 
ATOM   3515  C  CA   . GLY   A 1 228 ? 11.773  32.866  62.869  1.00 143.15 ?  227 GLY   B CA   1 
ATOM   3516  C  C    . GLY   A 1 228 ? 12.769  31.727  62.844  1.00 161.97 ?  227 GLY   B C    1 
ATOM   3517  O  O    . GLY   A 1 228 ? 13.909  31.934  62.455  1.00 212.77 ?  227 GLY   B O    1 
ATOM   3518  H  H    . GLY   A 1 228 ? 11.914  34.170  61.440  1.00 179.61 ?  227 GLY   B H    1 
ATOM   3519  H  HA2  . GLY   A 1 228 ? 12.137  33.572  63.426  1.00 171.78 ?  227 GLY   B HA2  1 
ATOM   3520  H  HA3  . GLY   A 1 228 ? 10.905  32.618  63.222  1.00 171.78 ?  227 GLY   B HA3  1 
ATOM   3521  N  N    . LYS   A 1 229 ? 12.356  30.539  63.282  1.00 162.78 ?  228 LYS   B N    1 
ATOM   3522  C  CA   . LYS   A 1 229 ? 13.172  29.330  63.225  1.00 156.47 ?  228 LYS   B CA   1 
ATOM   3523  C  C    . LYS   A 1 229 ? 12.217  28.130  63.330  1.00 145.61 ?  228 LYS   B C    1 
ATOM   3524  O  O    . LYS   A 1 229 ? 11.355  28.112  64.192  1.00 151.48 ?  228 LYS   B O    1 
ATOM   3525  C  CB   . LYS   A 1 229 ? 14.205  29.263  64.338  1.00 147.93 ?  228 LYS   B CB   1 
ATOM   3526  C  CG   . LYS   A 1 229 ? 13.830  29.974  65.618  1.00 148.91 ?  228 LYS   B CG   1 
ATOM   3527  C  CD   . LYS   A 1 229 ? 12.522  29.486  66.207  1.00 146.90 ?  228 LYS   B CD   1 
ATOM   3528  C  CE   . LYS   A 1 229 ? 12.342  30.053  67.600  1.00 148.45 ?  228 LYS   B CE   1 
ATOM   3529  N  NZ   . LYS   A 1 229 ? 13.287  29.442  68.564  1.00 156.30 ?  228 LYS   B NZ   1 
ATOM   3530  H  H    . LYS   A 1 229 ? 11.591  30.372  63.639  1.00 195.34 ?  228 LYS   B H    1 
ATOM   3531  H  HA   . LYS   A 1 229 ? 13.654  29.336  62.373  1.00 187.77 ?  228 LYS   B HA   1 
ATOM   3532  H  HB2  . LYS   A 1 229 ? 14.359  28.331  64.557  1.00 177.52 ?  228 LYS   B HB2  1 
ATOM   3533  H  HB3  . LYS   A 1 229 ? 15.028  29.660  64.015  1.00 177.52 ?  228 LYS   B HB3  1 
ATOM   3534  H  HG2  . LYS   A 1 229 ? 14.526  29.816  66.276  1.00 178.69 ?  228 LYS   B HG2  1 
ATOM   3535  H  HG3  . LYS   A 1 229 ? 13.751  30.925  65.450  1.00 178.69 ?  228 LYS   B HG3  1 
ATOM   3536  H  HD2  . LYS   A 1 229 ? 11.784  29.786  65.652  1.00 176.28 ?  228 LYS   B HD2  1 
ATOM   3537  H  HD3  . LYS   A 1 229 ? 12.533  28.518  66.266  1.00 176.28 ?  228 LYS   B HD3  1 
ATOM   3538  H  HE2  . LYS   A 1 229 ? 12.506  31.009  67.579  1.00 178.14 ?  228 LYS   B HE2  1 
ATOM   3539  H  HE3  . LYS   A 1 229 ? 11.438  29.875  67.904  1.00 178.14 ?  228 LYS   B HE3  1 
ATOM   3540  H  HZ1  . LYS   A 1 229 ? 14.104  29.945  68.587  1.00 187.56 ?  228 LYS   B HZ1  1 
ATOM   3541  H  HZ2  . LYS   A 1 229 ? 12.899  29.436  69.442  1.00 187.56 ?  228 LYS   B HZ2  1 
ATOM   3542  H  HZ3  . LYS   A 1 229 ? 13.483  28.539  68.303  1.00 187.56 ?  228 LYS   B HZ3  1 
ATOM   3543  N  N    . GLN   A 1 230 ? 12.359  27.137  62.457  1.00 140.44 ?  229 GLN   B N    1 
ATOM   3544  C  CA   . GLN   A 1 230 ? 11.508  25.936  62.454  1.00 122.98 ?  229 GLN   B CA   1 
ATOM   3545  C  C    . GLN   A 1 230 ? 9.985   26.105  62.608  1.00 107.48 ?  229 GLN   B C    1 
ATOM   3546  O  O    . GLN   A 1 230 ? 9.419   25.836  63.675  1.00 106.52 ?  229 GLN   B O    1 
ATOM   3547  C  CB   . GLN   A 1 230 ? 11.999  24.919  63.483  1.00 108.34 ?  229 GLN   B CB   1 
ATOM   3548  C  CG   . GLN   A 1 230 ? 12.931  23.883  62.892  1.00 86.93  ?  229 GLN   B CG   1 
ATOM   3549  C  CD   . GLN   A 1 230 ? 12.781  22.513  63.519  1.00 85.41  ?  229 GLN   B CD   1 
ATOM   3550  O  OE1  . GLN   A 1 230 ? 12.105  22.340  64.526  1.00 77.52  ?  229 GLN   B OE1  1 
ATOM   3551  N  NE2  . GLN   A 1 230 ? 13.423  21.532  62.921  1.00 73.24  ?  229 GLN   B NE2  1 
ATOM   3552  H  H    . GLN   A 1 230 ? 12.956  27.116  61.838  1.00 168.52 ?  229 GLN   B H    1 
ATOM   3553  H  HA   . GLN   A 1 230 ? 11.640  25.510  61.581  1.00 147.57 ?  229 GLN   B HA   1 
ATOM   3554  H  HB2  . GLN   A 1 230 ? 12.476  25.376  64.194  1.00 130.01 ?  229 GLN   B HB2  1 
ATOM   3555  H  HB3  . GLN   A 1 230 ? 11.232  24.452  63.851  1.00 130.01 ?  229 GLN   B HB3  1 
ATOM   3556  H  HG2  . GLN   A 1 230 ? 12.744  23.798  61.943  1.00 104.31 ?  229 GLN   B HG2  1 
ATOM   3557  H  HG3  . GLN   A 1 230 ? 13.847  24.173  63.023  1.00 104.31 ?  229 GLN   B HG3  1 
ATOM   3558  H  HE21 . GLN   A 1 230 ? 13.709  21.634  62.116  1.00 87.89  ?  229 GLN   B HE21 1 
ATOM   3559  H  HE22 . GLN   A 1 230 ? 13.557  20.790  63.334  1.00 87.89  ?  229 GLN   B HE22 1 
ATOM   3560  N  N    . ALA   A 1 231 ? 9.332   26.498  61.514  1.00 99.04  ?  230 ALA   B N    1 
ATOM   3561  C  CA   . ALA   A 1 231 ? 7.881   26.629  61.445  1.00 100.90 ?  230 ALA   B CA   1 
ATOM   3562  C  C    . ALA   A 1 231 ? 7.227   25.265  61.162  1.00 92.42  ?  230 ALA   B C    1 
ATOM   3563  O  O    . ALA   A 1 231 ? 7.928   24.284  60.936  1.00 81.94  ?  230 ALA   B O    1 
ATOM   3564  C  CB   . ALA   A 1 231 ? 7.519   27.605  60.356  1.00 95.87  ?  230 ALA   B CB   1 
ATOM   3565  H  H    . ALA   A 1 231 ? 9.721   26.704  60.775  1.00 118.84 ?  230 ALA   B H    1 
ATOM   3566  H  HA   . ALA   A 1 231 ? 7.541   26.969  62.299  1.00 121.08 ?  230 ALA   B HA   1 
ATOM   3567  H  HB1  . ALA   A 1 231 ? 6.682   28.020  60.576  1.00 115.04 ?  230 ALA   B HB1  1 
ATOM   3568  H  HB2  . ALA   A 1 231 ? 8.208   28.270  60.292  1.00 115.04 ?  230 ALA   B HB2  1 
ATOM   3569  H  HB3  . ALA   A 1 231 ? 7.441   27.131  59.525  1.00 115.04 ?  230 ALA   B HB3  1 
ATOM   3570  N  N    . THR   A 1 232 ? 5.896   25.186  61.177  1.00 84.08  ?  231 THR   B N    1 
ATOM   3571  C  CA   . THR   A 1 232 ? 5.235   23.913  60.902  1.00 72.46  ?  231 THR   B CA   1 
ATOM   3572  C  C    . THR   A 1 232 ? 4.512   23.991  59.600  1.00 66.23  ?  231 THR   B C    1 
ATOM   3573  O  O    . THR   A 1 232 ? 3.963   25.014  59.270  1.00 69.48  ?  231 THR   B O    1 
ATOM   3574  C  CB   . THR   A 1 232 ? 4.218   23.531  61.952  1.00 67.25  ?  231 THR   B CB   1 
ATOM   3575  O  OG1  . THR   A 1 232 ? 4.749   23.864  63.221  1.00 89.21  ?  231 THR   B OG1  1 
ATOM   3576  C  CG2  . THR   A 1 232 ? 3.904   22.074  61.924  1.00 60.83  ?  231 THR   B CG2  1 
ATOM   3577  H  H    . THR   A 1 232 ? 5.363   25.841  61.341  1.00 100.90 ?  231 THR   B H    1 
ATOM   3578  H  HA   . THR   A 1 232 ? 5.931   23.224  60.889  1.00 86.96  ?  231 THR   B HA   1 
ATOM   3579  H  HB   . THR   A 1 232 ? 3.389   23.960  61.771  1.00 80.70  ?  231 THR   B HB   1 
ATOM   3580  H  HG1  . THR   A 1 232 ? 4.643   23.239  63.742  1.00 107.05 ?  231 THR   B HG1  1 
ATOM   3581  H  HG21 . THR   A 1 232 ? 3.612   21.786  62.792  1.00 72.99  ?  231 THR   B HG21 1 
ATOM   3582  H  HG22 . THR   A 1 232 ? 3.209   21.901  61.286  1.00 72.99  ?  231 THR   B HG22 1 
ATOM   3583  H  HG23 . THR   A 1 232 ? 4.686   21.576  61.677  1.00 72.99  ?  231 THR   B HG23 1 
ATOM   3584  N  N    . LYS   A 1 233 ? 4.525   22.907  58.846  1.00 63.88  ?  232 LYS   B N    1 
ATOM   3585  C  CA   . LYS   A 1 233 ? 3.867   22.890  57.570  1.00 57.83  ?  232 LYS   B CA   1 
ATOM   3586  C  C    . LYS   A 1 233 ? 2.819   21.824  57.662  1.00 56.80  ?  232 LYS   B C    1 
ATOM   3587  O  O    . LYS   A 1 233 ? 3.142   20.749  58.069  1.00 56.78  ?  232 LYS   B O    1 
ATOM   3588  C  CB   . LYS   A 1 233 ? 4.868   22.465  56.517  1.00 53.99  ?  232 LYS   B CB   1 
ATOM   3589  C  CG   . LYS   A 1 233 ? 4.745   23.107  55.170  1.00 49.36  ?  232 LYS   B CG   1 
ATOM   3590  C  CD   . LYS   A 1 233 ? 5.186   22.230  54.057  1.00 50.87  ?  232 LYS   B CD   1 
ATOM   3591  C  CE   . LYS   A 1 233 ? 5.592   23.094  52.902  1.00 63.03  ?  232 LYS   B CE   1 
ATOM   3592  N  NZ   . LYS   A 1 233 ? 6.989   22.843  52.491  1.00 66.13  ?  232 LYS   B NZ   1 
ATOM   3593  H  H    . LYS   A 1 233 ? 4.904   22.154  59.018  1.00 76.66  ?  232 LYS   B H    1 
ATOM   3594  H  HA   . LYS   A 1 233 ? 3.512   23.778  57.354  1.00 69.39  ?  232 LYS   B HA   1 
ATOM   3595  H  HB2  . LYS   A 1 233 ? 5.758   22.662  56.847  1.00 64.79  ?  232 LYS   B HB2  1 
ATOM   3596  H  HB3  . LYS   A 1 233 ? 4.780   21.508  56.386  1.00 64.79  ?  232 LYS   B HB3  1 
ATOM   3597  H  HG2  . LYS   A 1 233 ? 3.837   23.410  55.011  1.00 59.24  ?  232 LYS   B HG2  1 
ATOM   3598  H  HG3  . LYS   A 1 233 ? 5.376   23.834  55.137  1.00 59.24  ?  232 LYS   B HG3  1 
ATOM   3599  H  HD2  . LYS   A 1 233 ? 5.950   21.702  54.337  1.00 61.05  ?  232 LYS   B HD2  1 
ATOM   3600  H  HD3  . LYS   A 1 233 ? 4.454   21.658  53.778  1.00 61.05  ?  232 LYS   B HD3  1 
ATOM   3601  H  HE2  . LYS   A 1 233 ? 5.016   22.906  52.145  1.00 75.64  ?  232 LYS   B HE2  1 
ATOM   3602  H  HE3  . LYS   A 1 233 ? 5.515   24.027  53.158  1.00 75.64  ?  232 LYS   B HE3  1 
ATOM   3603  H  HZ1  . LYS   A 1 233 ? 7.242   23.458  51.798  1.00 79.36  ?  232 LYS   B HZ1  1 
ATOM   3604  H  HZ2  . LYS   A 1 233 ? 7.577   22.958  53.240  1.00 79.36  ?  232 LYS   B HZ2  1 
ATOM   3605  H  HZ3  . LYS   A 1 233 ? 7.076   21.946  52.160  1.00 79.36  ?  232 LYS   B HZ3  1 
ATOM   3606  N  N    . TYR   A 1 234 ? 1.573   22.111  57.337  1.00 51.07  ?  233 TYR   B N    1 
ATOM   3607  C  CA   . TYR   A 1 234 ? 0.555   21.061  57.332  1.00 52.36  ?  233 TYR   B CA   1 
ATOM   3608  C  C    . TYR   A 1 234 ? -0.415  21.178  56.155  1.00 42.30  ?  233 TYR   B C    1 
ATOM   3609  O  O    . TYR   A 1 234 ? -0.666  22.260  55.620  1.00 44.47  ?  233 TYR   B O    1 
ATOM   3610  C  CB   . TYR   A 1 234 ? -0.196  21.023  58.684  1.00 53.89  ?  233 TYR   B CB   1 
ATOM   3611  C  CG   . TYR   A 1 234 ? -1.181  22.153  58.971  1.00 64.10  ?  233 TYR   B CG   1 
ATOM   3612  C  CD1  . TYR   A 1 234 ? -2.553  22.020  58.678  1.00 54.94  ?  233 TYR   B CD1  1 
ATOM   3613  C  CD2  . TYR   A 1 234 ? -0.759  23.329  59.586  1.00 72.37  ?  233 TYR   B CD2  1 
ATOM   3614  C  CE1  . TYR   A 1 234 ? -3.449  23.043  58.949  1.00 58.27  ?  233 TYR   B CE1  1 
ATOM   3615  C  CE2  . TYR   A 1 234 ? -1.672  24.352  59.873  1.00 72.40  ?  233 TYR   B CE2  1 
ATOM   3616  C  CZ   . TYR   A 1 234 ? -3.007  24.202  59.551  1.00 60.80  ?  233 TYR   B CZ   1 
ATOM   3617  O  OH   . TYR   A 1 234 ? -3.882  25.225  59.827  1.00 64.65  ?  233 TYR   B OH   1 
ATOM   3618  H  H    . TYR   A 1 234 ? 1.319   22.881  57.052  1.00 61.29  ?  233 TYR   B H    1 
ATOM   3619  H  HA   . TYR   A 1 234 ? 1.001   20.212  57.187  1.00 62.83  ?  233 TYR   B HA   1 
ATOM   3620  H  HB2  . TYR   A 1 234 ? -0.699  20.195  58.722  1.00 64.67  ?  233 TYR   B HB2  1 
ATOM   3621  H  HB3  . TYR   A 1 234 ? 0.466   21.042  59.393  1.00 64.67  ?  233 TYR   B HB3  1 
ATOM   3622  H  HD1  . TYR   A 1 234 ? -2.864  21.231  58.295  1.00 65.93  ?  233 TYR   B HD1  1 
ATOM   3623  H  HD2  . TYR   A 1 234 ? 0.138   23.436  59.808  1.00 86.85  ?  233 TYR   B HD2  1 
ATOM   3624  H  HE1  . TYR   A 1 234 ? -4.347  22.948  58.726  1.00 69.93  ?  233 TYR   B HE1  1 
ATOM   3625  H  HE2  . TYR   A 1 234 ? -1.379  25.134  60.281  1.00 86.88  ?  233 TYR   B HE2  1 
ATOM   3626  H  HH   . TYR   A 1 234 ? -3.478  25.853  60.212  1.00 77.59  ?  233 TYR   B HH   1 
ATOM   3627  N  N    . LEU   A 1 235 ? -0.935  20.021  55.749  1.00 40.32  ?  234 LEU   B N    1 
ATOM   3628  C  CA   . LEU   A 1 235 ? -1.839  19.917  54.604  1.00 43.63  ?  234 LEU   B CA   1 
ATOM   3629  C  C    . LEU   A 1 235 ? -3.226  20.441  54.950  1.00 36.71  ?  234 LEU   B C    1 
ATOM   3630  O  O    . LEU   A 1 235 ? -3.874  19.958  55.877  1.00 39.08  ?  234 LEU   B O    1 
ATOM   3631  C  CB   . LEU   A 1 235 ? -1.945  18.464  54.160  1.00 39.89  ?  234 LEU   B CB   1 
ATOM   3632  C  CG   . LEU   A 1 235 ? -2.661  18.179  52.856  1.00 37.02  ?  234 LEU   B CG   1 
ATOM   3633  C  CD1  . LEU   A 1 235 ? -2.054  18.799  51.639  1.00 41.20  ?  234 LEU   B CD1  1 
ATOM   3634  C  CD2  . LEU   A 1 235 ? -2.677  16.645  52.710  1.00 37.83  ?  234 LEU   B CD2  1 
ATOM   3635  H  H    . LEU   A 1 235 ? -0.777  19.265  56.127  1.00 48.39  ?  234 LEU   B H    1 
ATOM   3636  H  HA   . LEU   A 1 235 ? -1.481  20.456  53.882  1.00 52.36  ?  234 LEU   B HA   1 
ATOM   3637  H  HB2  . LEU   A 1 235 ? -1.044  18.117  54.066  1.00 47.87  ?  234 LEU   B HB2  1 
ATOM   3638  H  HB3  . LEU   A 1 235 ? -2.418  17.976  54.852  1.00 47.87  ?  234 LEU   B HB3  1 
ATOM   3639  H  HG   . LEU   A 1 235 ? -3.546  18.574  52.896  1.00 44.42  ?  234 LEU   B HG   1 
ATOM   3640  H  HD11 . LEU   A 1 235 ? -2.627  18.623  50.876  1.00 49.44  ?  234 LEU   B HD11 1 
ATOM   3641  H  HD12 . LEU   A 1 235 ? -1.974  19.755  51.778  1.00 49.44  ?  234 LEU   B HD12 1 
ATOM   3642  H  HD13 . LEU   A 1 235 ? -1.178  18.411  51.490  1.00 49.44  ?  234 LEU   B HD13 1 
ATOM   3643  H  HD21 . LEU   A 1 235 ? -1.922  16.371  52.167  1.00 45.39  ?  234 LEU   B HD21 1 
ATOM   3644  H  HD22 . LEU   A 1 235 ? -2.614  16.244  53.591  1.00 45.39  ?  234 LEU   B HD22 1 
ATOM   3645  H  HD23 . LEU   A 1 235 ? -3.506  16.377  52.283  1.00 45.39  ?  234 LEU   B HD23 1 
ATOM   3646  N  N    . VAL   A 1 236 ? -3.673  21.442  54.228  1.00 37.00  ?  235 VAL   B N    1 
ATOM   3647  C  CA   . VAL   A 1 236 ? -5.003  21.980  54.452  1.00 43.89  ?  235 VAL   B CA   1 
ATOM   3648  C  C    . VAL   A 1 236 ? -6.029  21.253  53.601  1.00 39.11  ?  235 VAL   B C    1 
ATOM   3649  O  O    . VAL   A 1 236 ? -7.007  20.726  54.123  1.00 42.00  ?  235 VAL   B O    1 
ATOM   3650  C  CB   . VAL   A 1 236 ? -5.011  23.493  54.159  1.00 46.42  ?  235 VAL   B CB   1 
ATOM   3651  C  CG1  . VAL   A 1 236 ? -6.421  23.971  54.042  1.00 42.11  ?  235 VAL   B CG1  1 
ATOM   3652  C  CG2  . VAL   A 1 236 ? -4.289  24.222  55.248  1.00 51.94  ?  235 VAL   B CG2  1 
ATOM   3653  H  H    . VAL   A 1 236 ? -3.230  21.830  53.601  1.00 44.40  ?  235 VAL   B H    1 
ATOM   3654  H  HA   . VAL   A 1 236 ? -5.238  21.853  55.385  1.00 52.66  ?  235 VAL   B HA   1 
ATOM   3655  H  HB   . VAL   A 1 236 ? -4.556  23.673  53.321  1.00 55.70  ?  235 VAL   B HB   1 
ATOM   3656  H  HG11 . VAL   A 1 236 ? -6.425  24.941  54.026  1.00 50.53  ?  235 VAL   B HG11 1 
ATOM   3657  H  HG12 . VAL   A 1 236 ? -6.804  23.625  53.221  1.00 50.53  ?  235 VAL   B HG12 1 
ATOM   3658  H  HG13 . VAL   A 1 236 ? -6.927  23.650  54.804  1.00 50.53  ?  235 VAL   B HG13 1 
ATOM   3659  H  HG21 . VAL   A 1 236 ? -4.291  25.171  55.047  1.00 62.32  ?  235 VAL   B HG21 1 
ATOM   3660  H  HG22 . VAL   A 1 236 ? -4.743  24.061  56.090  1.00 62.32  ?  235 VAL   B HG22 1 
ATOM   3661  H  HG23 . VAL   A 1 236 ? -3.377  23.895  55.296  1.00 62.32  ?  235 VAL   B HG23 1 
ATOM   3662  N  N    . GLN   A 1 237 ? -5.803  21.198  52.288  1.00 41.83  ?  236 GLN   B N    1 
ATOM   3663  C  CA   . GLN   A 1 237 ? -6.681  20.506  51.375  1.00 41.25  ?  236 GLN   B CA   1 
ATOM   3664  C  C    . GLN   A 1 237 ? -5.928  19.777  50.280  1.00 38.82  ?  236 GLN   B C    1 
ATOM   3665  O  O    . GLN   A 1 237 ? -4.936  20.281  49.758  1.00 41.39  ?  236 GLN   B O    1 
ATOM   3666  C  CB   . GLN   A 1 237 ? -7.622  21.504  50.751  1.00 40.42  ?  236 GLN   B CB   1 
ATOM   3667  C  CG   . GLN   A 1 237 ? -8.247  20.967  49.524  1.00 45.96  ?  236 GLN   B CG   1 
ATOM   3668  C  CD   . GLN   A 1 237 ? -9.684  21.368  49.442  1.00 51.86  ?  236 GLN   B CD   1 
ATOM   3669  O  OE1  . GLN   A 1 237 ? -10.552 20.680  49.967  1.00 51.44  ?  236 GLN   B OE1  1 
ATOM   3670  N  NE2  . GLN   A 1 237 ? -9.948  22.502  48.793  1.00 53.53  ?  236 GLN   B NE2  1 
ATOM   3671  H  H    . GLN   A 1 237 ? -5.128  21.565  51.903  1.00 50.19  ?  236 GLN   B H    1 
ATOM   3672  H  HA   . GLN   A 1 237 ? -7.160  19.819  51.864  1.00 49.49  ?  236 GLN   B HA   1 
ATOM   3673  H  HB2  . GLN   A 1 237 ? -8.326  21.718  51.383  1.00 48.51  ?  236 GLN   B HB2  1 
ATOM   3674  H  HB3  . GLN   A 1 237 ? -7.130  22.306  50.518  1.00 48.51  ?  236 GLN   B HB3  1 
ATOM   3675  H  HG2  . GLN   A 1 237 ? -7.784  21.316  48.746  1.00 55.15  ?  236 GLN   B HG2  1 
ATOM   3676  H  HG3  . GLN   A 1 237 ? -8.197  19.998  49.533  1.00 55.15  ?  236 GLN   B HG3  1 
ATOM   3677  H  HE21 . GLN   A 1 237 ? -9.307  22.960  48.449  1.00 64.24  ?  236 GLN   B HE21 1 
ATOM   3678  H  HE22 . GLN   A 1 237 ? -10.760 22.775  48.719  1.00 64.24  ?  236 GLN   B HE22 1 
ATOM   3679  N  N    . GLN   A 1 238 ? -6.458  18.611  49.897  1.00 40.57  ?  237 GLN   B N    1 
ATOM   3680  C  CA   . GLN   A 1 238 ? -5.897  17.830  48.806  1.00 38.19  ?  237 GLN   B CA   1 
ATOM   3681  C  C    . GLN   A 1 238 ? -6.997  17.312  47.894  1.00 37.99  ?  237 GLN   B C    1 
ATOM   3682  O  O    . GLN   A 1 238 ? -7.934  16.666  48.348  1.00 39.94  ?  237 GLN   B O    1 
ATOM   3683  C  CB   . GLN   A 1 238 ? -5.071  16.658  49.355  1.00 43.32  ?  237 GLN   B CB   1 
ATOM   3684  C  CG   . GLN   A 1 238 ? -4.391  15.820  48.291  1.00 37.77  ?  237 GLN   B CG   1 
ATOM   3685  C  CD   . GLN   A 1 238 ? -3.132  16.482  47.778  1.00 41.45  ?  237 GLN   B CD   1 
ATOM   3686  O  OE1  . GLN   A 1 238 ? -2.426  17.194  48.513  1.00 40.15  ?  237 GLN   B OE1  1 
ATOM   3687  N  NE2  . GLN   A 1 238 ? -2.814  16.216  46.514  1.00 37.72  ?  237 GLN   B NE2  1 
ATOM   3688  H  H    . GLN   A 1 238 ? -7.149  18.252  50.262  1.00 48.69  ?  237 GLN   B H    1 
ATOM   3689  H  HA   . GLN   A 1 238 ? -5.329  18.404  48.268  1.00 45.83  ?  237 GLN   B HA   1 
ATOM   3690  H  HB2  . GLN   A 1 238 ? -4.380  17.012  49.937  1.00 51.99  ?  237 GLN   B HB2  1 
ATOM   3691  H  HB3  . GLN   A 1 238 ? -5.660  16.073  49.858  1.00 51.99  ?  237 GLN   B HB3  1 
ATOM   3692  H  HG2  . GLN   A 1 238 ? -4.150  14.959  48.668  1.00 45.33  ?  237 GLN   B HG2  1 
ATOM   3693  H  HG3  . GLN   A 1 238 ? -4.997  15.697  47.544  1.00 45.33  ?  237 GLN   B HG3  1 
ATOM   3694  H  HE21 . GLN   A 1 238 ? -3.314  15.696  46.045  1.00 45.27  ?  237 GLN   B HE21 1 
ATOM   3695  H  HE22 . GLN   A 1 238 ? -2.109  16.564  46.166  1.00 45.27  ?  237 GLN   B HE22 1 
ATOM   3696  N  N    . GLU   A 1 239 ? -6.872  17.574  46.607  1.00 41.15  ?  238 GLU   B N    1 
ATOM   3697  C  CA   . GLU   A 1 239 ? -7.797  17.047  45.619  1.00 41.02  ?  238 GLU   B CA   1 
ATOM   3698  C  C    . GLU   A 1 239 ? -6.981  16.427  44.513  1.00 39.37  ?  238 GLU   B C    1 
ATOM   3699  O  O    . GLU   A 1 239 ? -6.394  17.152  43.706  1.00 50.49  ?  238 GLU   B O    1 
ATOM   3700  C  CB   . GLU   A 1 239 ? -8.693  18.145  45.074  1.00 45.61  ?  238 GLU   B CB   1 
ATOM   3701  C  CG   . GLU   A 1 239 ? -9.764  18.553  46.076  1.00 56.58  ?  238 GLU   B CG   1 
ATOM   3702  C  CD   . GLU   A 1 239 ? -10.516 19.791  45.653  1.00 71.53  ?  238 GLU   B CD   1 
ATOM   3703  O  OE1  . GLU   A 1 239 ? -11.222 20.342  46.536  1.00 71.80  ?  238 GLU   B OE1  1 
ATOM   3704  O  OE2  . GLU   A 1 239 ? -10.411 20.194  44.455  1.00 72.97  -1 238 GLU   B OE2  1 
ATOM   3705  H  H    . GLU   A 1 239 ? -6.249  18.064  46.274  1.00 49.38  ?  238 GLU   B H    1 
ATOM   3706  H  HA   . GLU   A 1 239 ? -8.356  16.364  46.021  1.00 49.22  ?  238 GLU   B HA   1 
ATOM   3707  H  HB2  . GLU   A 1 239 ? -8.153  18.925  44.871  1.00 54.73  ?  238 GLU   B HB2  1 
ATOM   3708  H  HB3  . GLU   A 1 239 ? -9.133  17.828  44.270  1.00 54.73  ?  238 GLU   B HB3  1 
ATOM   3709  H  HG2  . GLU   A 1 239 ? -10.404 17.829  46.166  1.00 67.90  ?  238 GLU   B HG2  1 
ATOM   3710  H  HG3  . GLU   A 1 239 ? -9.345  18.734  46.931  1.00 67.90  ?  238 GLU   B HG3  1 
ATOM   3711  N  N    . SER   A 1 240 ? -6.952  15.098  44.471  1.00 30.26  ?  239 SER   B N    1 
ATOM   3712  C  CA   . SER   A 1 240 ? -6.171  14.366  43.481  1.00 35.56  ?  239 SER   B CA   1 
ATOM   3713  C  C    . SER   A 1 240 ? -6.457  12.886  43.679  1.00 30.86  ?  239 SER   B C    1 
ATOM   3714  O  O    . SER   A 1 240 ? -6.885  12.478  44.763  1.00 25.87  ?  239 SER   B O    1 
ATOM   3715  C  CB   . SER   A 1 240 ? -4.672  14.658  43.651  1.00 37.46  ?  239 SER   B CB   1 
ATOM   3716  O  OG   . SER   A 1 240 ? -4.211  14.120  44.910  1.00 36.98  ?  239 SER   B OG   1 
ATOM   3717  H  H    . SER   A 1 240 ? -7.383  14.590  45.015  1.00 36.31  ?  239 SER   B H    1 
ATOM   3718  H  HA   . SER   A 1 240 ? -6.414  14.630  42.580  1.00 42.68  ?  239 SER   B HA   1 
ATOM   3719  H  HB2  . SER   A 1 240 ? -4.181  14.242  42.925  1.00 44.95  ?  239 SER   B HB2  1 
ATOM   3720  H  HB3  . SER   A 1 240 ? -4.530  15.617  43.641  1.00 44.95  ?  239 SER   B HB3  1 
ATOM   3721  H  HG   . SER   A 1 240 ? -3.381  14.226  44.981  1.00 44.38  ?  239 SER   B HG   1 
ATOM   3722  N  N    . PRO   A 1 241 ? -6.233  12.052  42.668  1.00 28.75  ?  240 PRO   B N    1 
ATOM   3723  C  CA   . PRO   A 1 241 ? -6.451  10.608  42.839  1.00 28.54  ?  240 PRO   B CA   1 
ATOM   3724  C  C    . PRO   A 1 241 ? -5.359  9.904   43.646  1.00 33.23  ?  240 PRO   B C    1 
ATOM   3725  O  O    . PRO   A 1 241 ? -5.574  8.752   44.065  1.00 29.32  ?  240 PRO   B O    1 
ATOM   3726  C  CB   . PRO   A 1 241 ? -6.507  10.084  41.396  1.00 34.86  ?  240 PRO   B CB   1 
ATOM   3727  C  CG   . PRO   A 1 241 ? -5.765  11.065  40.579  1.00 31.02  ?  240 PRO   B CG   1 
ATOM   3728  C  CD   . PRO   A 1 241 ? -5.821  12.413  41.309  1.00 33.65  ?  240 PRO   B CD   1 
ATOM   3729  H  HA   . PRO   A 1 241 ? -7.308  10.451  43.266  1.00 34.25  ?  240 PRO   B HA   1 
ATOM   3730  H  HB2  . PRO   A 1 241 ? -6.088  9.211   41.349  1.00 41.83  ?  240 PRO   B HB2  1 
ATOM   3731  H  HB3  . PRO   A 1 241 ? -7.431  10.024  41.106  1.00 41.83  ?  240 PRO   B HB3  1 
ATOM   3732  H  HG2  . PRO   A 1 241 ? -4.846  10.772  40.484  1.00 37.22  ?  240 PRO   B HG2  1 
ATOM   3733  H  HG3  . PRO   A 1 241 ? -6.183  11.137  39.707  1.00 37.22  ?  240 PRO   B HG3  1 
ATOM   3734  H  HD2  . PRO   A 1 241 ? -4.949  12.838  41.315  1.00 40.38  ?  240 PRO   B HD2  1 
ATOM   3735  H  HD3  . PRO   A 1 241 ? -6.474  13.001  40.897  1.00 40.38  ?  240 PRO   B HD3  1 
ATOM   3736  N  N    . PHE   A 1 242 ? -4.216  10.548  43.885  1.00 32.70  ?  241 PHE   B N    1 
ATOM   3737  C  CA   . PHE   A 1 242 ? -3.143  9.924   44.652  1.00 28.02  ?  241 PHE   B CA   1 
ATOM   3738  C  C    . PHE   A 1 242 ? -2.237  11.025  45.166  1.00 23.81  ?  241 PHE   B C    1 
ATOM   3739  O  O    . PHE   A 1 242 ? -2.266  12.153  44.681  1.00 27.74  ?  241 PHE   B O    1 
ATOM   3740  C  CB   . PHE   A 1 242 ? -2.339  8.884   43.840  1.00 29.96  ?  241 PHE   B CB   1 
ATOM   3741  C  CG   . PHE   A 1 242 ? -1.567  9.467   42.683  1.00 28.04  ?  241 PHE   B CG   1 
ATOM   3742  C  CD1  . PHE   A 1 242 ? -2.185  9.645   41.444  1.00 31.66  ?  241 PHE   B CD1  1 
ATOM   3743  C  CD2  . PHE   A 1 242 ? -0.299  9.900   42.837  1.00 29.25  ?  241 PHE   B CD2  1 
ATOM   3744  C  CE1  . PHE   A 1 242 ? -1.522  10.221  40.385  1.00 32.33  ?  241 PHE   B CE1  1 
ATOM   3745  C  CE2  . PHE   A 1 242 ? 0.364   10.475  41.792  1.00 37.60  ?  241 PHE   B CE2  1 
ATOM   3746  C  CZ   . PHE   A 1 242 ? -0.257  10.637  40.562  1.00 36.58  ?  241 PHE   B CZ   1 
ATOM   3747  H  H    . PHE   A 1 242 ? -4.039  11.345  43.614  1.00 39.24  ?  241 PHE   B H    1 
ATOM   3748  H  HA   . PHE   A 1 242 ? -3.532  9.450   45.403  1.00 33.63  ?  241 PHE   B HA   1 
ATOM   3749  H  HB2  . PHE   A 1 242 ? -1.702  8.454   44.432  1.00 35.95  ?  241 PHE   B HB2  1 
ATOM   3750  H  HB3  . PHE   A 1 242 ? -2.955  8.226   43.481  1.00 35.95  ?  241 PHE   B HB3  1 
ATOM   3751  H  HD1  . PHE   A 1 242 ? -3.066  9.368   41.332  1.00 37.99  ?  241 PHE   B HD1  1 
ATOM   3752  H  HD2  . PHE   A 1 242 ? 0.126   9.806   43.659  1.00 35.11  ?  241 PHE   B HD2  1 
ATOM   3753  H  HE1  . PHE   A 1 242 ? -1.942  10.320  39.561  1.00 38.80  ?  241 PHE   B HE1  1 
ATOM   3754  H  HE2  . PHE   A 1 242 ? 1.242   10.761  41.905  1.00 45.11  ?  241 PHE   B HE2  1 
ATOM   3755  H  HZ   . PHE   A 1 242 ? 0.204   11.034  39.859  1.00 43.89  ?  241 PHE   B HZ   1 
ATOM   3756  N  N    . VAL   A 1 243 ? -1.459  10.695  46.189  1.00 22.23  ?  242 VAL   B N    1 
ATOM   3757  C  CA   . VAL   A 1 243 ? -0.286  11.504  46.522  1.00 36.93  ?  242 VAL   B CA   1 
ATOM   3758  C  C    . VAL   A 1 243 ? 0.961   10.623  46.635  1.00 34.24  ?  242 VAL   B C    1 
ATOM   3759  O  O    . VAL   A 1 243 ? 0.891   9.439   46.988  1.00 31.58  ?  242 VAL   B O    1 
ATOM   3760  C  CB   . VAL   A 1 243 ? -0.469  12.313  47.837  1.00 30.12  ?  242 VAL   B CB   1 
ATOM   3761  C  CG1  . VAL   A 1 243 ? -1.716  13.142  47.757  1.00 32.49  ?  242 VAL   B CG1  1 
ATOM   3762  C  CG2  . VAL   A 1 243 ? -0.516  11.372  49.009  1.00 32.67  ?  242 VAL   B CG2  1 
ATOM   3763  H  H    . VAL   A 1 243 ? -1.586  10.016  46.701  1.00 26.68  ?  242 VAL   B H    1 
ATOM   3764  H  HA   . VAL   A 1 243 ? -0.152  12.122  45.786  1.00 44.32  ?  242 VAL   B HA   1 
ATOM   3765  H  HB   . VAL   A 1 243 ? 0.282   12.914  47.963  1.00 36.15  ?  242 VAL   B HB   1 
ATOM   3766  H  HG11 . VAL   A 1 243 ? -1.979  13.402  48.653  1.00 38.98  ?  242 VAL   B HG11 1 
ATOM   3767  H  HG12 . VAL   A 1 243 ? -1.537  13.931  47.222  1.00 38.98  ?  242 VAL   B HG12 1 
ATOM   3768  H  HG13 . VAL   A 1 243 ? -2.419  12.616  47.345  1.00 38.98  ?  242 VAL   B HG13 1 
ATOM   3769  H  HG21 . VAL   A 1 243 ? -0.798  11.863  49.796  1.00 39.21  ?  242 VAL   B HG21 1 
ATOM   3770  H  HG22 . VAL   A 1 243 ? -1.148  10.661  48.818  1.00 39.21  ?  242 VAL   B HG22 1 
ATOM   3771  H  HG23 . VAL   A 1 243 ? 0.368   10.999  49.150  1.00 39.21  ?  242 VAL   B HG23 1 
ATOM   3772  N  N    . MET   A 1 244 ? 2.124   11.242  46.431  1.00 39.31  ?  243 MET   B N    1 
ATOM   3773  C  CA   . MET   A 1 244 ? 3.412   10.560  46.505  1.00 32.42  ?  243 MET   B CA   1 
ATOM   3774  C  C    . MET   A 1 244 ? 4.268   11.247  47.560  1.00 32.43  ?  243 MET   B C    1 
ATOM   3775  O  O    . MET   A 1 244 ? 4.564   12.441  47.457  1.00 28.13  ?  243 MET   B O    1 
ATOM   3776  C  CB   . MET   A 1 244 ? 4.072   10.559  45.130  1.00 30.65  ?  243 MET   B CB   1 
ATOM   3777  C  CG   . MET   A 1 244 ? 5.422   9.931   45.094  1.00 42.07  ?  243 MET   B CG   1 
ATOM   3778  S  SD   . MET   A 1 244 ? 6.183   10.140  43.438  1.00 36.50  ?  243 MET   B SD   1 
ATOM   3779  C  CE   . MET   A 1 244 ? 7.645   9.179   43.806  1.00 34.30  ?  243 MET   B CE   1 
ATOM   3780  H  H    . MET   A 1 244 ? 2.192   12.079  46.245  1.00 47.17  ?  243 MET   B H    1 
ATOM   3781  H  HA   . MET   A 1 244 ? 3.297   9.637   46.778  1.00 38.90  ?  243 MET   B HA   1 
ATOM   3782  H  HB2  . MET   A 1 244 ? 3.504   10.069  44.515  1.00 36.78  ?  243 MET   B HB2  1 
ATOM   3783  H  HB3  . MET   A 1 244 ? 4.168   11.478  44.833  1.00 36.78  ?  243 MET   B HB3  1 
ATOM   3784  H  HG2  . MET   A 1 244 ? 5.994   10.353  45.753  1.00 50.49  ?  243 MET   B HG2  1 
ATOM   3785  H  HG3  . MET   A 1 244 ? 5.343   8.982   45.281  1.00 50.49  ?  243 MET   B HG3  1 
ATOM   3786  H  HE1  . MET   A 1 244 ? 8.235   9.195   43.037  1.00 41.16  ?  243 MET   B HE1  1 
ATOM   3787  H  HE2  . MET   A 1 244 ? 8.093   9.567   44.574  1.00 41.16  ?  243 MET   B HE2  1 
ATOM   3788  H  HE3  . MET   A 1 244 ? 7.382   8.267   44.003  1.00 41.16  ?  243 MET   B HE3  1 
ATOM   3789  N  N    . MET   A 1 245 ? 4.594   10.511  48.607  1.00 31.55  ?  244 MET   B N    1 
ATOM   3790  C  CA   . MET   A 1 245 ? 5.380   11.023  49.719  1.00 31.57  ?  244 MET   B CA   1 
ATOM   3791  C  C    . MET   A 1 245 ? 6.761   10.398  49.591  1.00 34.96  ?  244 MET   B C    1 
ATOM   3792  O  O    . MET   A 1 245 ? 6.873   9.166   49.550  1.00 32.62  ?  244 MET   B O    1 
ATOM   3793  C  CB   . MET   A 1 245 ? 4.758   10.654  51.065  1.00 34.71  ?  244 MET   B CB   1 
ATOM   3794  C  CG   . MET   A 1 245 ? 3.328   11.088  51.263  1.00 30.77  ?  244 MET   B CG   1 
ATOM   3795  S  SD   . MET   A 1 245 ? 3.122   12.887  51.165  1.00 32.78  ?  244 MET   B SD   1 
ATOM   3796  C  CE   . MET   A 1 245 ? 3.979   13.445  52.629  1.00 31.35  ?  244 MET   B CE   1 
ATOM   3797  H  H    . MET   A 1 245 ? 4.365   9.688   48.701  1.00 37.86  ?  244 MET   B H    1 
ATOM   3798  H  HA   . MET   A 1 245 ? 5.425   11.991  49.680  1.00 37.88  ?  244 MET   B HA   1 
ATOM   3799  H  HB2  . MET   A 1 245 ? 4.782   9.689   51.158  1.00 41.65  ?  244 MET   B HB2  1 
ATOM   3800  H  HB3  . MET   A 1 245 ? 5.284   11.068  51.767  1.00 41.65  ?  244 MET   B HB3  1 
ATOM   3801  H  HG2  . MET   A 1 245 ? 2.777   10.685  50.574  1.00 36.92  ?  244 MET   B HG2  1 
ATOM   3802  H  HG3  . MET   A 1 245 ? 3.028   10.799  52.139  1.00 36.92  ?  244 MET   B HG3  1 
ATOM   3803  H  HE1  . MET   A 1 245 ? 3.905   14.410  52.689  1.00 37.62  ?  244 MET   B HE1  1 
ATOM   3804  H  HE2  . MET   A 1 245 ? 3.574   13.032  53.408  1.00 37.62  ?  244 MET   B HE2  1 
ATOM   3805  H  HE3  . MET   A 1 245 ? 4.912   13.187  52.565  1.00 37.62  ?  244 MET   B HE3  1 
ATOM   3806  N  N    . SER   A 1 246 ? 7.805   11.235  49.535  1.00 25.69  ?  245 SER   B N    1 
ATOM   3807  C  CA   . SER   A 1 246 ? 9.149   10.735  49.341  1.00 33.62  ?  245 SER   B CA   1 
ATOM   3808  C  C    . SER   A 1 246 ? 10.094  11.313  50.378  1.00 36.65  ?  245 SER   B C    1 
ATOM   3809  O  O    . SER   A 1 246 ? 9.875   12.417  50.910  1.00 29.68  ?  245 SER   B O    1 
ATOM   3810  C  CB   . SER   A 1 246 ? 9.681   11.087  47.937  1.00 37.11  ?  245 SER   B CB   1 
ATOM   3811  O  OG   . SER   A 1 246 ? 9.004   10.336  46.928  1.00 36.55  ?  245 SER   B OG   1 
ATOM   3812  H  H    . SER   A 1 246 ? 7.749   12.090  49.606  1.00 30.82  ?  245 SER   B H    1 
ATOM   3813  H  HA   . SER   A 1 246 ? 9.137   9.771   49.451  1.00 40.35  ?  245 SER   B HA   1 
ATOM   3814  H  HB2  . SER   A 1 246 ? 9.538   12.033  47.774  1.00 44.53  ?  245 SER   B HB2  1 
ATOM   3815  H  HB3  . SER   A 1 246 ? 10.629  10.883  47.899  1.00 44.53  ?  245 SER   B HB3  1 
ATOM   3816  H  HG   . SER   A 1 246 ? 9.273   10.569  46.167  1.00 43.86  ?  245 SER   B HG   1 
ATOM   3817  N  N    . ALA   A 1 247 ? 11.177  10.570  50.616  1.00 33.74  ?  246 ALA   B N    1 
ATOM   3818  C  CA   . ALA   A 1 247 ? 12.245  11.034  51.488  1.00 34.25  ?  246 ALA   B CA   1 
ATOM   3819  C  C    . ALA   A 1 247 ? 13.478  10.189  51.231  1.00 33.56  ?  246 ALA   B C    1 
ATOM   3820  O  O    . ALA   A 1 247 ? 13.375  9.066   50.711  1.00 25.42  ?  246 ALA   B O    1 
ATOM   3821  C  CB   . ALA   A 1 247 ? 11.827  10.936  52.960  1.00 34.35  ?  246 ALA   B CB   1 
ATOM   3822  H  H    . ALA   A 1 247 ? 11.312  9.790   50.280  1.00 40.49  ?  246 ALA   B H    1 
ATOM   3823  H  HA   . ALA   A 1 247 ? 12.459  11.957  51.282  1.00 41.11  ?  246 ALA   B HA   1 
ATOM   3824  H  HB1  . ALA   A 1 247 ? 12.594  11.137  53.520  1.00 41.22  ?  246 ALA   B HB1  1 
ATOM   3825  H  HB2  . ALA   A 1 247 ? 11.117  11.574  53.131  1.00 41.22  ?  246 ALA   B HB2  1 
ATOM   3826  H  HB3  . ALA   A 1 247 ? 11.513  10.036  53.140  1.00 41.22  ?  246 ALA   B HB3  1 
ATOM   3827  N  N    . PRO   A 1 248 ? 14.654  10.689  51.597  1.00 36.76  ?  247 PRO   B N    1 
ATOM   3828  C  CA   . PRO   A 1 248 ? 15.861  9.887   51.474  1.00 31.05  ?  247 PRO   B CA   1 
ATOM   3829  C  C    . PRO   A 1 248 ? 15.704  8.592   52.242  1.00 33.53  ?  247 PRO   B C    1 
ATOM   3830  O  O    . PRO   A 1 248 ? 15.194  8.581   53.380  1.00 31.37  ?  247 PRO   B O    1 
ATOM   3831  C  CB   . PRO   A 1 248 ? 16.956  10.777  52.098  1.00 34.94  ?  247 PRO   B CB   1 
ATOM   3832  C  CG   . PRO   A 1 248 ? 16.481  12.167  51.830  1.00 37.48  ?  247 PRO   B CG   1 
ATOM   3833  C  CD   . PRO   A 1 248 ? 14.953  12.065  52.045  1.00 40.49  ?  247 PRO   B CD   1 
ATOM   3834  H  HA   . PRO   A 1 248 ? 16.078  9.711   50.545  1.00 37.26  ?  247 PRO   B HA   1 
ATOM   3835  H  HB2  . PRO   A 1 248 ? 17.023  10.606  53.051  1.00 41.93  ?  247 PRO   B HB2  1 
ATOM   3836  H  HB3  . PRO   A 1 248 ? 17.809  10.608  51.669  1.00 41.93  ?  247 PRO   B HB3  1 
ATOM   3837  H  HG2  . PRO   A 1 248 ? 16.886  12.788  52.455  1.00 44.98  ?  247 PRO   B HG2  1 
ATOM   3838  H  HG3  . PRO   A 1 248 ? 16.694  12.427  50.920  1.00 44.98  ?  247 PRO   B HG3  1 
ATOM   3839  H  HD2  . PRO   A 1 248 ? 14.725  12.183  52.980  1.00 48.59  ?  247 PRO   B HD2  1 
ATOM   3840  H  HD3  . PRO   A 1 248 ? 14.482  12.717  51.503  1.00 48.59  ?  247 PRO   B HD3  1 
ATOM   3841  N  N    . PRO   A 1 249 ? 16.182  7.491   51.672  1.00 29.90  ?  248 PRO   B N    1 
ATOM   3842  C  CA   . PRO   A 1 249 ? 15.911  6.176   52.255  1.00 35.39  ?  248 PRO   B CA   1 
ATOM   3843  C  C    . PRO   A 1 249 ? 16.229  6.117   53.735  1.00 34.35  ?  248 PRO   B C    1 
ATOM   3844  O  O    . PRO   A 1 249 ? 17.251  6.612   54.186  1.00 37.74  ?  248 PRO   B O    1 
ATOM   3845  C  CB   . PRO   A 1 249 ? 16.823  5.231   51.455  1.00 26.07  ?  248 PRO   B CB   1 
ATOM   3846  C  CG   . PRO   A 1 249 ? 17.513  6.053   50.410  1.00 35.35  ?  248 PRO   B CG   1 
ATOM   3847  C  CD   . PRO   A 1 249 ? 16.864  7.395   50.369  1.00 36.24  ?  248 PRO   B CD   1 
ATOM   3848  H  HA   . PRO   A 1 249 ? 14.979  5.945   52.116  1.00 42.46  ?  248 PRO   B HA   1 
ATOM   3849  H  HB2  . PRO   A 1 249 ? 17.473  4.830   52.053  1.00 31.29  ?  248 PRO   B HB2  1 
ATOM   3850  H  HB3  . PRO   A 1 249 ? 16.283  4.540   51.040  1.00 31.29  ?  248 PRO   B HB3  1 
ATOM   3851  H  HG2  . PRO   A 1 249 ? 18.450  6.141   50.644  1.00 42.42  ?  248 PRO   B HG2  1 
ATOM   3852  H  HG3  . PRO   A 1 249 ? 17.425  5.612   49.551  1.00 42.42  ?  248 PRO   B HG3  1 
ATOM   3853  H  HD2  . PRO   A 1 249 ? 17.529  8.095   50.276  1.00 43.49  ?  248 PRO   B HD2  1 
ATOM   3854  H  HD3  . PRO   A 1 249 ? 16.225  7.446   49.641  1.00 43.49  ?  248 PRO   B HD3  1 
ATOM   3855  N  N    . ALA   A 1 250 ? 15.353  5.466   54.477  1.00 34.52  ?  249 ALA   B N    1 
ATOM   3856  C  CA   . ALA   A 1 250 ? 15.503  5.300   55.912  1.00 37.28  ?  249 ALA   B CA   1 
ATOM   3857  C  C    . ALA   A 1 250 ? 14.609  4.147   56.341  1.00 29.72  ?  249 ALA   B C    1 
ATOM   3858  O  O    . ALA   A 1 250 ? 13.634  3.786   55.669  1.00 30.19  ?  249 ALA   B O    1 
ATOM   3859  C  CB   . ALA   A 1 250 ? 15.151  6.568   56.686  1.00 31.09  ?  249 ALA   B CB   1 
ATOM   3860  H  H    . ALA   A 1 250 ? 14.641  5.098   54.165  1.00 41.43  ?  249 ALA   B H    1 
ATOM   3861  H  HA   . ALA   A 1 250 ? 16.427  5.084   56.114  1.00 44.73  ?  249 ALA   B HA   1 
ATOM   3862  H  HB1  . ALA   A 1 250 ? 15.228  6.389   57.637  1.00 37.31  ?  249 ALA   B HB1  1 
ATOM   3863  H  HB2  . ALA   A 1 250 ? 15.765  7.274   56.432  1.00 37.31  ?  249 ALA   B HB2  1 
ATOM   3864  H  HB3  . ALA   A 1 250 ? 14.241  6.826   56.471  1.00 37.31  ?  249 ALA   B HB3  1 
ATOM   3865  N  N    . GLN   A 1 251 ? 15.012  3.526   57.427  1.00 32.26  ?  250 GLN   B N    1 
ATOM   3866  C  CA   . GLN   A 1 251 ? 14.276  2.389   57.941  1.00 38.79  ?  250 GLN   B CA   1 
ATOM   3867  C  C    . GLN   A 1 251 ? 12.895  2.840   58.393  1.00 32.69  ?  250 GLN   B C    1 
ATOM   3868  O  O    . GLN   A 1 251 ? 12.719  3.928   58.959  1.00 27.02  ?  250 GLN   B O    1 
ATOM   3869  C  CB   . GLN   A 1 251 ? 15.024  1.737   59.102  1.00 41.97  ?  250 GLN   B CB   1 
ATOM   3870  C  CG   . GLN   A 1 251 ? 14.492  0.324   59.413  1.00 38.05  ?  250 GLN   B CG   1 
ATOM   3871  C  CD   . GLN   A 1 251 ? 15.106  -0.681  58.457  1.00 45.36  ?  250 GLN   B CD   1 
ATOM   3872  O  OE1  . GLN   A 1 251 ? 15.842  -0.300  57.519  1.00 43.26  ?  250 GLN   B OE1  1 
ATOM   3873  N  NE2  . GLN   A 1 251 ? 14.832  -1.980  58.699  1.00 37.18  ?  250 GLN   B NE2  1 
ATOM   3874  H  H    . GLN   A 1 251 ? 15.706  3.740   57.887  1.00 38.71  ?  250 GLN   B H    1 
ATOM   3875  H  HA   . GLN   A 1 251 ? 14.179  1.720   57.246  1.00 46.55  ?  250 GLN   B HA   1 
ATOM   3876  H  HB2  . GLN   A 1 251 ? 15.964  1.664   58.874  1.00 50.37  ?  250 GLN   B HB2  1 
ATOM   3877  H  HB3  . GLN   A 1 251 ? 14.917  2.283   59.897  1.00 50.37  ?  250 GLN   B HB3  1 
ATOM   3878  H  HG2  . GLN   A 1 251 ? 14.730  0.078   60.320  1.00 45.65  ?  250 GLN   B HG2  1 
ATOM   3879  H  HG3  . GLN   A 1 251 ? 13.528  0.307   59.306  1.00 45.65  ?  250 GLN   B HG3  1 
ATOM   3880  H  HE21 . GLN   A 1 251 ? 14.333  -2.197  59.365  1.00 44.62  ?  250 GLN   B HE21 1 
ATOM   3881  H  HE22 . GLN   A 1 251 ? 15.155  -2.590  58.187  1.00 44.62  ?  250 GLN   B HE22 1 
ATOM   3882  N  N    . TYR   A 1 252 ? 11.908  2.003   58.101  1.00 35.50  ?  251 TYR   B N    1 
ATOM   3883  C  CA   . TYR   A 1 252 ? 10.530  2.459   58.067  1.00 31.07  ?  251 TYR   B CA   1 
ATOM   3884  C  C    . TYR   A 1 252 ? 9.599   1.259   58.078  1.00 34.78  ?  251 TYR   B C    1 
ATOM   3885  O  O    . TYR   A 1 252 ? 9.838   0.278   57.382  1.00 33.86  ?  251 TYR   B O    1 
ATOM   3886  C  CB   . TYR   A 1 252 ? 10.296  3.320   56.814  1.00 35.15  ?  251 TYR   B CB   1 
ATOM   3887  C  CG   . TYR   A 1 252 ? 9.039   4.104   56.848  1.00 41.20  ?  251 TYR   B CG   1 
ATOM   3888  C  CD1  . TYR   A 1 252 ? 7.874   3.555   56.339  1.00 44.71  ?  251 TYR   B CD1  1 
ATOM   3889  C  CD2  . TYR   A 1 252 ? 9.000   5.389   57.400  1.00 37.47  ?  251 TYR   B CD2  1 
ATOM   3890  C  CE1  . TYR   A 1 252 ? 6.687   4.248   56.388  1.00 51.44  ?  251 TYR   B CE1  1 
ATOM   3891  C  CE2  . TYR   A 1 252 ? 7.823   6.099   57.445  1.00 48.54  ?  251 TYR   B CE2  1 
ATOM   3892  C  CZ   . TYR   A 1 252 ? 6.662   5.518   56.923  1.00 49.45  ?  251 TYR   B CZ   1 
ATOM   3893  O  OH   . TYR   A 1 252 ? 5.483   6.187   56.930  1.00 40.35  ?  251 TYR   B OH   1 
ATOM   3894  H  H    . TYR   A 1 252 ? 12.013  1.169   57.921  1.00 42.60  ?  251 TYR   B H    1 
ATOM   3895  H  HA   . TYR   A 1 252 ? 10.329  2.984   58.858  1.00 37.28  ?  251 TYR   B HA   1 
ATOM   3896  H  HB2  . TYR   A 1 252 ? 11.032  3.946   56.725  1.00 42.18  ?  251 TYR   B HB2  1 
ATOM   3897  H  HB3  . TYR   A 1 252 ? 10.260  2.738   56.039  1.00 42.18  ?  251 TYR   B HB3  1 
ATOM   3898  H  HD1  . TYR   A 1 252 ? 7.895   2.707   55.958  1.00 53.65  ?  251 TYR   B HD1  1 
ATOM   3899  H  HD2  . TYR   A 1 252 ? 9.779   5.767   57.740  1.00 44.96  ?  251 TYR   B HD2  1 
ATOM   3900  H  HE1  . TYR   A 1 252 ? 5.906   3.862   56.062  1.00 61.73  ?  251 TYR   B HE1  1 
ATOM   3901  H  HE2  . TYR   A 1 252 ? 7.800   6.951   57.817  1.00 58.24  ?  251 TYR   B HE2  1 
ATOM   3902  H  HH   . TYR   A 1 252 ? 5.463   6.727   57.573  1.00 48.41  ?  251 TYR   B HH   1 
ATOM   3903  N  N    . GLU   A 1 253 ? 8.538   1.342   58.873  1.00 43.05  ?  252 GLU   B N    1 
ATOM   3904  C  CA   . GLU   A 1 253 ? 7.595   0.244   59.028  1.00 41.35  ?  252 GLU   B CA   1 
ATOM   3905  C  C    . GLU   A 1 253 ? 6.344   0.507   58.190  1.00 39.80  ?  252 GLU   B C    1 
ATOM   3906  O  O    . GLU   A 1 253 ? 5.773   1.601   58.225  1.00 38.72  ?  252 GLU   B O    1 
ATOM   3907  C  CB   . GLU   A 1 253 ? 7.254   0.073   60.506  1.00 40.85  ?  252 GLU   B CB   1 
ATOM   3908  C  CG   . GLU   A 1 253 ? 6.099   -0.824  60.824  1.00 54.70  ?  252 GLU   B CG   1 
ATOM   3909  C  CD   . GLU   A 1 253 ? 5.962   -1.058  62.322  1.00 56.32  ?  252 GLU   B CD   1 
ATOM   3910  O  OE1  . GLU   A 1 253 ? 5.975   -0.068  63.105  1.00 52.94  ?  252 GLU   B OE1  1 
ATOM   3911  O  OE2  . GLU   A 1 253 ? 5.850   -2.249  62.700  1.00 63.91  -1 252 GLU   B OE2  1 
ATOM   3912  H  H    . GLU   A 1 253 ? 8.341   2.036   59.341  1.00 51.66  ?  252 GLU   B H    1 
ATOM   3913  H  HA   . GLU   A 1 253 ? 7.979   -0.585  58.703  1.00 49.62  ?  252 GLU   B HA   1 
ATOM   3914  H  HB2  . GLU   A 1 253 ? 8.032   -0.295  60.954  1.00 49.02  ?  252 GLU   B HB2  1 
ATOM   3915  H  HB3  . GLU   A 1 253 ? 7.044   0.947   60.870  1.00 49.02  ?  252 GLU   B HB3  1 
ATOM   3916  H  HG2  . GLU   A 1 253 ? 5.280   -0.417  60.504  1.00 65.64  ?  252 GLU   B HG2  1 
ATOM   3917  H  HG3  . GLU   A 1 253 ? 6.233   -1.683  60.394  1.00 65.64  ?  252 GLU   B HG3  1 
ATOM   3918  N  N    . LEU   A 1 254 ? 5.928   -0.492  57.430  1.00 43.20  ?  253 LEU   B N    1 
ATOM   3919  C  CA   . LEU   A 1 254 ? 4.766   -0.363  56.556  1.00 41.25  ?  253 LEU   B CA   1 
ATOM   3920  C  C    . LEU   A 1 254 ? 3.671   -1.301  57.013  1.00 38.95  ?  253 LEU   B C    1 
ATOM   3921  O  O    . LEU   A 1 254 ? 3.905   -2.503  57.152  1.00 38.12  ?  253 LEU   B O    1 
ATOM   3922  C  CB   . LEU   A 1 254 ? 5.107   -0.705  55.106  1.00 36.00  ?  253 LEU   B CB   1 
ATOM   3923  C  CG   . LEU   A 1 254 ? 5.939   0.304   54.331  1.00 34.87  ?  253 LEU   B CG   1 
ATOM   3924  C  CD1  . LEU   A 1 254 ? 6.377   -0.427  53.071  1.00 39.35  ?  253 LEU   B CD1  1 
ATOM   3925  C  CD2  . LEU   A 1 254 ? 5.215   1.539   53.940  1.00 36.34  ?  253 LEU   B CD2  1 
ATOM   3926  H  H    . LEU   A 1 254 ? 6.305   -1.265  57.400  1.00 51.84  ?  253 LEU   B H    1 
ATOM   3927  H  HA   . LEU   A 1 254 ? 4.455   0.554   56.609  1.00 49.50  ?  253 LEU   B HA   1 
ATOM   3928  H  HB2  . LEU   A 1 254 ? 5.603   -1.539  55.106  1.00 43.20  ?  253 LEU   B HB2  1 
ATOM   3929  H  HB3  . LEU   A 1 254 ? 4.274   -0.815  54.622  1.00 43.20  ?  253 LEU   B HB3  1 
ATOM   3930  H  HG   . LEU   A 1 254 ? 6.668   0.614   54.891  1.00 41.85  ?  253 LEU   B HG   1 
ATOM   3931  H  HD11 . LEU   A 1 254 ? 6.789   0.209   52.464  1.00 47.21  ?  253 LEU   B HD11 1 
ATOM   3932  H  HD12 . LEU   A 1 254 ? 7.016   -1.115  53.311  1.00 47.21  ?  253 LEU   B HD12 1 
ATOM   3933  H  HD13 . LEU   A 1 254 ? 5.600   -0.828  52.652  1.00 47.21  ?  253 LEU   B HD13 1 
ATOM   3934  H  HD21 . LEU   A 1 254 ? 5.837   2.147   53.509  1.00 43.61  ?  253 LEU   B HD21 1 
ATOM   3935  H  HD22 . LEU   A 1 254 ? 4.502   1.306   53.325  1.00 43.61  ?  253 LEU   B HD22 1 
ATOM   3936  H  HD23 . LEU   A 1 254 ? 4.844   1.954   54.734  1.00 43.61  ?  253 LEU   B HD23 1 
ATOM   3937  N  N    . LYS   A 1 255 ? 2.469   -0.777  57.161  1.00 42.41  ?  254 LYS   B N    1 
ATOM   3938  C  CA   . LYS   A 1 255 ? 1.341   -1.547  57.679  1.00 50.09  ?  254 LYS   B CA   1 
ATOM   3939  C  C    . LYS   A 1 255 ? 0.253   -1.749  56.630  1.00 37.18  ?  254 LYS   B C    1 
ATOM   3940  O  O    . LYS   A 1 255 ? -0.161  -0.798  55.964  1.00 37.07  ?  254 LYS   B O    1 
ATOM   3941  C  CB   . LYS   A 1 255 ? 0.754   -0.843  58.909  1.00 54.08  ?  254 LYS   B CB   1 
ATOM   3942  C  CG   . LYS   A 1 255 ? 1.650   -0.840  60.153  1.00 55.21  ?  254 LYS   B CG   1 
ATOM   3943  C  CD   . LYS   A 1 255 ? 2.148   -2.248  60.471  1.00 66.54  ?  254 LYS   B CD   1 
ATOM   3944  C  CE   . LYS   A 1 255 ? 1.320   -2.940  61.578  1.00 63.54  ?  254 LYS   B CE   1 
ATOM   3945  N  NZ   . LYS   A 1 255 ? 2.213   -3.783  62.461  1.00 76.68  ?  254 LYS   B NZ   1 
ATOM   3946  H  H    . LYS   A 1 255 ? 2.273   0.038   56.967  1.00 50.89  ?  254 LYS   B H    1 
ATOM   3947  H  HA   . LYS   A 1 255 ? 1.658   -2.432  57.916  1.00 60.11  ?  254 LYS   B HA   1 
ATOM   3948  H  HB2  . LYS   A 1 255 ? 0.578   0.082   58.677  1.00 64.89  ?  254 LYS   B HB2  1 
ATOM   3949  H  HB3  . LYS   A 1 255 ? -0.074  -1.288  59.150  1.00 64.89  ?  254 LYS   B HB3  1 
ATOM   3950  H  HG2  . LYS   A 1 255 ? 2.419   -0.270  59.996  1.00 66.25  ?  254 LYS   B HG2  1 
ATOM   3951  H  HG3  . LYS   A 1 255 ? 1.145   -0.514  60.914  1.00 66.25  ?  254 LYS   B HG3  1 
ATOM   3952  H  HD2  . LYS   A 1 255 ? 2.091   -2.792  59.670  1.00 79.85  ?  254 LYS   B HD2  1 
ATOM   3953  H  HD3  . LYS   A 1 255 ? 3.068   -2.197  60.773  1.00 79.85  ?  254 LYS   B HD3  1 
ATOM   3954  H  HE2  . LYS   A 1 255 ? 0.887   -2.268  62.127  1.00 76.24  ?  254 LYS   B HE2  1 
ATOM   3955  H  HE3  . LYS   A 1 255 ? 0.653   -3.516  61.172  1.00 76.24  ?  254 LYS   B HE3  1 
ATOM   3956  H  HZ1  . LYS   A 1 255 ? 1.728   -4.184  63.090  1.00 92.02  ?  254 LYS   B HZ1  1 
ATOM   3957  H  HZ2  . LYS   A 1 255 ? 2.625   -4.403  61.974  1.00 92.02  ?  254 LYS   B HZ2  1 
ATOM   3958  H  HZ3  . LYS   A 1 255 ? 2.826   -3.269  62.852  1.00 92.02  ?  254 LYS   B HZ3  1 
ATOM   3959  N  N    . HIS   A 1 256 ? -0.195  -2.995  56.504  1.00 38.67  ?  255 HIS   B N    1 
ATOM   3960  C  CA   . HIS   A 1 256 ? -1.239  -3.395  55.562  1.00 32.96  ?  255 HIS   B CA   1 
ATOM   3961  C  C    . HIS   A 1 256 ? -2.488  -2.548  55.703  1.00 37.12  ?  255 HIS   B C    1 
ATOM   3962  O  O    . HIS   A 1 256 ? -2.997  -2.366  56.802  1.00 38.39  ?  255 HIS   B O    1 
ATOM   3963  C  CB   . HIS   A 1 256 ? -1.572  -4.872  55.805  1.00 35.72  ?  255 HIS   B CB   1 
ATOM   3964  C  CG   . HIS   A 1 256 ? -2.719  -5.389  55.006  1.00 39.89  ?  255 HIS   B CG   1 
ATOM   3965  N  ND1  . HIS   A 1 256 ? -3.776  -6.037  55.592  1.00 39.19  ?  255 HIS   B ND1  1 
ATOM   3966  C  CD2  . HIS   A 1 256 ? -2.951  -5.412  53.670  1.00 43.19  ?  255 HIS   B CD2  1 
ATOM   3967  C  CE1  . HIS   A 1 256 ? -4.637  -6.405  54.656  1.00 49.30  ?  255 HIS   B CE1  1 
ATOM   3968  N  NE2  . HIS   A 1 256 ? -4.159  -6.044  53.479  1.00 47.59  ?  255 HIS   B NE2  1 
ATOM   3969  H  H    . HIS   A 1 256 ? 0.099   -3.655  56.971  1.00 46.41  ?  255 HIS   B H    1 
ATOM   3970  H  HA   . HIS   A 1 256 ? -0.917  -3.275  54.655  1.00 39.56  ?  255 HIS   B HA   1 
ATOM   3971  H  HB2  . HIS   A 1 256 ? -0.794  -5.405  55.578  1.00 42.86  ?  255 HIS   B HB2  1 
ATOM   3972  H  HB3  . HIS   A 1 256 ? -1.793  -4.989  56.742  1.00 42.86  ?  255 HIS   B HB3  1 
ATOM   3973  H  HD2  . HIS   A 1 256 ? -2.398  -5.067  53.007  1.00 51.82  ?  255 HIS   B HD2  1 
ATOM   3974  H  HE1  . HIS   A 1 256 ? -5.444  -6.844  54.803  1.00 59.15  ?  255 HIS   B HE1  1 
ATOM   3975  H  HE2  . HIS   A 1 256 ? -4.540  -6.181  52.720  1.00 57.11  ?  255 HIS   B HE2  1 
ATOM   3976  N  N    . GLY   A 1 257 ? -2.981  -2.049  54.572  1.00 36.35  ?  256 GLY   B N    1 
ATOM   3977  C  CA   . GLY   A 1 257 ? -4.141  -1.219  54.542  1.00 33.23  ?  256 GLY   B CA   1 
ATOM   3978  C  C    . GLY   A 1 257 ? -3.893  0.264   54.655  1.00 35.10  ?  256 GLY   B C    1 
ATOM   3979  O  O    . GLY   A 1 257 ? -4.768  1.050   54.310  1.00 34.77  ?  256 GLY   B O    1 
ATOM   3980  H  H    . GLY   A 1 257 ? -2.639  -2.190  53.795  1.00 43.62  ?  256 GLY   B H    1 
ATOM   3981  H  HA2  . GLY   A 1 257 ? -4.607  -1.373  53.705  1.00 39.87  ?  256 GLY   B HA2  1 
ATOM   3982  H  HA3  . GLY   A 1 257 ? -4.720  -1.474  55.277  1.00 39.87  ?  256 GLY   B HA3  1 
ATOM   3983  N  N    . THR   A 1 258 ? -2.723  0.692   55.087  1.00 33.89  ?  257 THR   B N    1 
ATOM   3984  C  CA   . THR   A 1 258 ? -2.482  2.116   55.322  1.00 34.40  ?  257 THR   B CA   1 
ATOM   3985  C  C    . THR   A 1 258 ? -1.719  2.790   54.194  1.00 26.44  ?  257 THR   B C    1 
ATOM   3986  O  O    . THR   A 1 258 ? -1.377  3.960   54.296  1.00 26.87  ?  257 THR   B O    1 
ATOM   3987  C  CB   . THR   A 1 258 ? -1.720  2.285   56.627  1.00 35.86  ?  257 THR   B CB   1 
ATOM   3988  O  OG1  . THR   A 1 258 ? -0.395  1.740   56.443  1.00 38.71  ?  257 THR   B OG1  1 
ATOM   3989  C  CG2  . THR   A 1 258 ? -2.488  1.536   57.695  1.00 33.61  ?  257 THR   B CG2  1 
ATOM   3990  H  H    . THR   A 1 258 ? -2.050  0.183   55.253  1.00 40.67  ?  257 THR   B H    1 
ATOM   3991  H  HA   . THR   A 1 258 ? -3.339  2.564   55.397  1.00 41.28  ?  257 THR   B HA   1 
ATOM   3992  H  HB   . THR   A 1 258 ? -1.628  3.211   56.902  1.00 43.03  ?  257 THR   B HB   1 
ATOM   3993  H  HG1  . THR   A 1 258 ? 0.065   1.866   57.134  1.00 46.46  ?  257 THR   B HG1  1 
ATOM   3994  H  HG21 . THR   A 1 258 ? -2.069  1.671   58.560  1.00 40.34  ?  257 THR   B HG21 1 
ATOM   3995  H  HG22 . THR   A 1 258 ? -3.402  1.859   57.734  1.00 40.34  ?  257 THR   B HG22 1 
ATOM   3996  H  HG23 . THR   A 1 258 ? -2.497  0.588   57.494  1.00 40.34  ?  257 THR   B HG23 1 
ATOM   3997  N  N    . PHE   A 1 259 ? -1.523  2.120   53.084  1.00 29.59  ?  258 PHE   B N    1 
ATOM   3998  C  CA   . PHE   A 1 259 ? -0.791  2.723   51.974  1.00 31.45  ?  258 PHE   B CA   1 
ATOM   3999  C  C    . PHE   A 1 259 ? -1.175  1.890   50.777  1.00 27.17  ?  258 PHE   B C    1 
ATOM   4000  O  O    . PHE   A 1 259 ? -1.739  0.806   50.916  1.00 29.95  ?  258 PHE   B O    1 
ATOM   4001  C  CB   . PHE   A 1 259 ? 0.740   2.782   52.269  1.00 28.58  ?  258 PHE   B CB   1 
ATOM   4002  C  CG   . PHE   A 1 259 ? 1.419   1.468   52.147  1.00 27.36  ?  258 PHE   B CG   1 
ATOM   4003  C  CD1  . PHE   A 1 259 ? 1.355   0.547   53.151  1.00 26.57  ?  258 PHE   B CD1  1 
ATOM   4004  C  CD2  . PHE   A 1 259 ? 2.123   1.140   50.993  1.00 36.78  ?  258 PHE   B CD2  1 
ATOM   4005  C  CE1  . PHE   A 1 259 ? 1.955   -0.692  53.012  1.00 27.12  ?  258 PHE   B CE1  1 
ATOM   4006  C  CE2  . PHE   A 1 259 ? 2.745   -0.117  50.864  1.00 29.29  ?  258 PHE   B CE2  1 
ATOM   4007  C  CZ   . PHE   A 1 259 ? 2.623   -1.029  51.884  1.00 24.89  ?  258 PHE   B CZ   1 
ATOM   4008  H  H    . PHE   A 1 259 ? -1.798  1.318   52.939  1.00 35.51  ?  258 PHE   B H    1 
ATOM   4009  H  HA   . PHE   A 1 259 ? -1.040  3.645   51.802  1.00 37.74  ?  258 PHE   B HA   1 
ATOM   4010  H  HB2  . PHE   A 1 259 ? 1.157   3.390   51.639  1.00 34.30  ?  258 PHE   B HB2  1 
ATOM   4011  H  HB3  . PHE   A 1 259 ? 0.872   3.101   53.176  1.00 34.30  ?  258 PHE   B HB3  1 
ATOM   4012  H  HD1  . PHE   A 1 259 ? 0.903   0.753   53.937  1.00 31.89  ?  258 PHE   B HD1  1 
ATOM   4013  H  HD2  . PHE   A 1 259 ? 2.185   1.757   50.300  1.00 44.13  ?  258 PHE   B HD2  1 
ATOM   4014  H  HE1  . PHE   A 1 259 ? 1.899   -1.305  53.709  1.00 32.54  ?  258 PHE   B HE1  1 
ATOM   4015  H  HE2  . PHE   A 1 259 ? 3.231   -0.327  50.100  1.00 35.15  ?  258 PHE   B HE2  1 
ATOM   4016  H  HZ   . PHE   A 1 259 ? 2.998   -1.876  51.800  1.00 29.87  ?  258 PHE   B HZ   1 
ATOM   4017  N  N    . THR   A 1 260 ? -0.852  2.378   49.601  1.00 34.15  ?  259 THR   B N    1 
ATOM   4018  C  CA   . THR   A 1 260 ? -1.120  1.590   48.414  1.00 29.62  ?  259 THR   B CA   1 
ATOM   4019  C  C    . THR   A 1 260 ? 0.135   0.859   47.933  1.00 31.95  ?  259 THR   B C    1 
ATOM   4020  O  O    . THR   A 1 260 ? 0.100   -0.360  47.759  1.00 27.89  ?  259 THR   B O    1 
ATOM   4021  C  CB   . THR   A 1 260 ? -1.673  2.465   47.302  1.00 27.84  ?  259 THR   B CB   1 
ATOM   4022  O  OG1  . THR   A 1 260 ? -3.027  2.817   47.609  1.00 49.28  ?  259 THR   B OG1  1 
ATOM   4023  C  CG2  . THR   A 1 260 ? -1.623  1.684   46.033  1.00 31.69  ?  259 THR   B CG2  1 
ATOM   4024  H  H    . THR   A 1 260 ? -0.485  3.144   49.466  1.00 40.98  ?  259 THR   B H    1 
ATOM   4025  H  HA   . THR   A 1 260 ? -1.802  0.932   48.619  1.00 35.54  ?  259 THR   B HA   1 
ATOM   4026  H  HB   . THR   A 1 260 ? -1.159  3.281   47.201  1.00 33.41  ?  259 THR   B HB   1 
ATOM   4027  H  HG1  . THR   A 1 260 ? -3.043  3.497   48.101  1.00 59.13  ?  259 THR   B HG1  1 
ATOM   4028  H  HG21 . THR   A 1 260 ? -2.254  2.050   45.393  1.00 38.03  ?  259 THR   B HG21 1 
ATOM   4029  H  HG22 . THR   A 1 260 ? -0.731  1.723   45.653  1.00 38.03  ?  259 THR   B HG22 1 
ATOM   4030  H  HG23 . THR   A 1 260 ? -1.852  0.757   46.204  1.00 38.03  ?  259 THR   B HG23 1 
ATOM   4031  N  N    . CYS   A 1 261 ? 1.238   1.571   47.694  1.00 27.27  ?  260 CYS   B N    1 
ATOM   4032  C  CA   . CYS   A 1 261 ? 2.494   0.905   47.364  1.00 25.59  ?  260 CYS   B CA   1 
ATOM   4033  C  C    . CYS   A 1 261 ? 3.652   1.845   47.633  1.00 30.39  ?  260 CYS   B C    1 
ATOM   4034  O  O    . CYS   A 1 261 ? 3.456   3.053   47.823  1.00 27.51  ?  260 CYS   B O    1 
ATOM   4035  C  CB   . CYS   A 1 261 ? 2.494   0.436   45.921  1.00 30.12  ?  260 CYS   B CB   1 
ATOM   4036  S  SG   . CYS   A 1 261 ? 2.348   1.804   44.781  1.00 35.21  ?  260 CYS   B SG   1 
ATOM   4037  H  H    . CYS   A 1 261 ? 1.281   2.429   47.717  1.00 32.73  ?  260 CYS   B H    1 
ATOM   4038  H  HA   . CYS   A 1 261 ? 2.605   0.136   47.945  1.00 30.71  ?  260 CYS   B HA   1 
ATOM   4039  H  HB2  . CYS   A 1 261 ? 3.325   -0.028  45.735  1.00 36.14  ?  260 CYS   B HB2  1 
ATOM   4040  H  HB3  . CYS   A 1 261 ? 1.742   -0.161  45.779  1.00 36.14  ?  260 CYS   B HB3  1 
ATOM   4041  H  HG   . CYS   A 1 261 ? 2.142   1.374   43.679  1.00 42.25  ?  260 CYS   B HG   1 
ATOM   4042  N  N    . ALA   A 1 262 ? 4.867   1.265   47.627  1.00 31.89  ?  261 ALA   B N    1 
ATOM   4043  C  CA   . ALA   A 1 262 ? 6.072   1.961   48.055  1.00 29.08  ?  261 ALA   B CA   1 
ATOM   4044  C  C    . ALA   A 1 262 ? 7.312   1.356   47.416  1.00 30.13  ?  261 ALA   B C    1 
ATOM   4045  O  O    . ALA   A 1 262 ? 7.307   0.213   46.940  1.00 30.96  ?  261 ALA   B O    1 
ATOM   4046  C  CB   . ALA   A 1 262 ? 6.245   1.931   49.587  1.00 33.42  ?  261 ALA   B CB   1 
ATOM   4047  H  H    . ALA   A 1 262 ? 5.011   0.456   47.374  1.00 38.26  ?  261 ALA   B H    1 
ATOM   4048  H  HA   . ALA   A 1 262 ? 5.991   2.878   47.749  1.00 34.90  ?  261 ALA   B HA   1 
ATOM   4049  H  HB1  . ALA   A 1 262 ? 7.087   2.352   49.818  1.00 40.11  ?  261 ALA   B HB1  1 
ATOM   4050  H  HB2  . ALA   A 1 262 ? 5.510   2.413   49.997  1.00 40.11  ?  261 ALA   B HB2  1 
ATOM   4051  H  HB3  . ALA   A 1 262 ? 6.243   1.008   49.887  1.00 40.11  ?  261 ALA   B HB3  1 
ATOM   4052  N  N    . SER   A 1 263 ? 8.383   2.158   47.414  1.00 34.73  ?  262 SER   B N    1 
ATOM   4053  C  CA   . SER   A 1 263 ? 9.675   1.810   46.823  1.00 32.04  ?  262 SER   B CA   1 
ATOM   4054  C  C    . SER   A 1 263 ? 10.695  1.584   47.925  1.00 29.93  ?  262 SER   B C    1 
ATOM   4055  O  O    . SER   A 1 263 ? 10.978  2.510   48.702  1.00 31.68  ?  262 SER   B O    1 
ATOM   4056  C  CB   . SER   A 1 263 ? 10.207  2.916   45.926  1.00 28.04  ?  262 SER   B CB   1 
ATOM   4057  O  OG   . SER   A 1 263 ? 9.275   3.179   44.945  1.00 32.00  ?  262 SER   B OG   1 
ATOM   4058  H  H    . SER   A 1 263 ? 8.382   2.943   47.766  1.00 41.67  ?  262 SER   B H    1 
ATOM   4059  H  HA   . SER   A 1 263 ? 9.546   0.998   46.309  1.00 38.45  ?  262 SER   B HA   1 
ATOM   4060  H  HB2  . SER   A 1 263 ? 10.357  3.717   46.453  1.00 33.64  ?  262 SER   B HB2  1 
ATOM   4061  H  HB3  . SER   A 1 263 ? 11.037  2.629   45.515  1.00 33.64  ?  262 SER   B HB3  1 
ATOM   4062  H  HG   . SER   A 1 263 ? 9.525   3.832   44.479  1.00 38.40  ?  262 SER   B HG   1 
ATOM   4063  N  N    . GLU   A 1 264 ? 11.198  0.354   48.033  1.00 26.92  ?  263 GLU   B N    1 
ATOM   4064  C  CA   . GLU   A 1 264 ? 12.294  0.051   48.946  1.00 36.57  ?  263 GLU   B CA   1 
ATOM   4065  C  C    . GLU   A 1 264 ? 13.594  0.306   48.187  1.00 30.30  ?  263 GLU   B C    1 
ATOM   4066  O  O    . GLU   A 1 264 ? 13.741  -0.137  47.051  1.00 29.36  ?  263 GLU   B O    1 
ATOM   4067  C  CB   . GLU   A 1 264 ? 12.229  -1.395  49.453  1.00 33.84  ?  263 GLU   B CB   1 
ATOM   4068  C  CG   . GLU   A 1 264 ? 13.541  -1.826  50.168  1.00 32.08  ?  263 GLU   B CG   1 
ATOM   4069  C  CD   . GLU   A 1 264 ? 13.632  -3.335  50.359  1.00 40.16  ?  263 GLU   B CD   1 
ATOM   4070  O  OE1  . GLU   A 1 264 ? 14.514  -3.957  49.695  1.00 42.87  ?  263 GLU   B OE1  1 
ATOM   4071  O  OE2  . GLU   A 1 264 ? 12.811  -3.899  51.156  1.00 40.82  -1 263 GLU   B OE2  1 
ATOM   4072  H  H    . GLU   A 1 264 ? 10.918  -0.324  47.584  1.00 32.31  ?  263 GLU   B H    1 
ATOM   4073  H  HA   . GLU   A 1 264 ? 12.249  0.614   49.734  1.00 43.88  ?  263 GLU   B HA   1 
ATOM   4074  H  HB2  . GLU   A 1 264 ? 11.498  -1.478  50.085  1.00 40.61  ?  263 GLU   B HB2  1 
ATOM   4075  H  HB3  . GLU   A 1 264 ? 12.085  -1.990  48.700  1.00 40.61  ?  263 GLU   B HB3  1 
ATOM   4076  H  HG2  . GLU   A 1 264 ? 14.300  -1.544  49.635  1.00 38.49  ?  263 GLU   B HG2  1 
ATOM   4077  H  HG3  . GLU   A 1 264 ? 13.576  -1.410  51.043  1.00 38.49  ?  263 GLU   B HG3  1 
ATOM   4078  N  N    . TYR   A 1 265 ? 14.539  1.002   48.805  1.00 27.90  ?  264 TYR   B N    1 
ATOM   4079  C  CA   . TYR   A 1 265 ? 15.850  1.196   48.179  1.00 30.97  ?  264 TYR   B CA   1 
ATOM   4080  C  C    . TYR   A 1 265 ? 16.946  0.696   49.119  1.00 30.28  ?  264 TYR   B C    1 
ATOM   4081  O  O    . TYR   A 1 265 ? 17.097  1.204   50.234  1.00 29.60  ?  264 TYR   B O    1 
ATOM   4082  C  CB   . TYR   A 1 265 ? 16.068  2.671   47.808  1.00 24.59  ?  264 TYR   B CB   1 
ATOM   4083  C  CG   . TYR   A 1 265 ? 17.334  2.925   47.021  1.00 32.85  ?  264 TYR   B CG   1 
ATOM   4084  C  CD1  . TYR   A 1 265 ? 17.382  2.708   45.660  1.00 32.85  ?  264 TYR   B CD1  1 
ATOM   4085  C  CD2  . TYR   A 1 265 ? 18.476  3.375   47.641  1.00 27.59  ?  264 TYR   B CD2  1 
ATOM   4086  C  CE1  . TYR   A 1 265 ? 18.557  2.919   44.925  1.00 31.87  ?  264 TYR   B CE1  1 
ATOM   4087  C  CE2  . TYR   A 1 265 ? 19.684  3.551   46.932  1.00 34.80  ?  264 TYR   B CE2  1 
ATOM   4088  C  CZ   . TYR   A 1 265 ? 19.698  3.337   45.582  1.00 36.28  ?  264 TYR   B CZ   1 
ATOM   4089  O  OH   . TYR   A 1 265 ? 20.823  3.587   44.836  1.00 21.13  ?  264 TYR   B OH   1 
ATOM   4090  H  H    . TYR   A 1 265 ? 14.449  1.368   49.578  1.00 33.48  ?  264 TYR   B H    1 
ATOM   4091  H  HA   . TYR   A 1 265 ? 15.899  0.665   47.369  1.00 37.17  ?  264 TYR   B HA   1 
ATOM   4092  H  HB2  . TYR   A 1 265 ? 15.320  2.969   47.268  1.00 29.51  ?  264 TYR   B HB2  1 
ATOM   4093  H  HB3  . TYR   A 1 265 ? 16.118  3.193   48.624  1.00 29.51  ?  264 TYR   B HB3  1 
ATOM   4094  H  HD1  . TYR   A 1 265 ? 16.617  2.414   45.220  1.00 39.41  ?  264 TYR   B HD1  1 
ATOM   4095  H  HD2  . TYR   A 1 265 ? 18.453  3.568   48.551  1.00 33.11  ?  264 TYR   B HD2  1 
ATOM   4096  H  HE1  . TYR   A 1 265 ? 18.568  2.779   44.005  1.00 38.25  ?  264 TYR   B HE1  1 
ATOM   4097  H  HE2  . TYR   A 1 265 ? 20.459  3.809   47.376  1.00 41.76  ?  264 TYR   B HE2  1 
ATOM   4098  H  HH   . TYR   A 1 265 ? 21.510  3.445   45.297  1.00 25.36  ?  264 TYR   B HH   1 
ATOM   4099  N  N    . THR   A 1 266 ? 17.749  -0.256  48.656  1.00 33.34  ?  265 THR   B N    1 
ATOM   4100  C  CA   . THR   A 1 266 ? 18.930  -0.680  49.400  1.00 34.52  ?  265 THR   B CA   1 
ATOM   4101  C  C    . THR   A 1 266 ? 20.195  -0.347  48.617  1.00 35.64  ?  265 THR   B C    1 
ATOM   4102  O  O    . THR   A 1 266 ? 20.226  -0.517  47.397  1.00 29.47  ?  265 THR   B O    1 
ATOM   4103  C  CB   . THR   A 1 266 ? 18.864  -2.165  49.678  1.00 30.65  ?  265 THR   B CB   1 
ATOM   4104  O  OG1  . THR   A 1 266 ? 18.904  -2.860  48.432  1.00 33.97  ?  265 THR   B OG1  1 
ATOM   4105  C  CG2  . THR   A 1 266 ? 17.556  -2.529  50.340  1.00 36.66  ?  265 THR   B CG2  1 
ATOM   4106  H  H    . THR   A 1 266 ? 17.630  -0.671  47.912  1.00 40.01  ?  265 THR   B H    1 
ATOM   4107  H  HA   . THR   A 1 266 ? 18.979  -0.203  50.243  1.00 41.42  ?  265 THR   B HA   1 
ATOM   4108  H  HB   . THR   A 1 266 ? 19.601  -2.415  50.257  1.00 36.78  ?  265 THR   B HB   1 
ATOM   4109  H  HG1  . THR   A 1 266 ? 18.623  -3.645  48.532  1.00 40.77  ?  265 THR   B HG1  1 
ATOM   4110  H  HG21 . THR   A 1 266 ? 17.510  -3.488  50.480  1.00 43.99  ?  265 THR   B HG21 1 
ATOM   4111  H  HG22 . THR   A 1 266 ? 17.481  -2.081  51.197  1.00 43.99  ?  265 THR   B HG22 1 
ATOM   4112  H  HG23 . THR   A 1 266 ? 16.813  -2.258  49.778  1.00 43.99  ?  265 THR   B HG23 1 
ATOM   4113  N  N    . GLY   A 1 267 ? 21.244  0.110   49.340  1.00 36.45  ?  266 GLY   B N    1 
ATOM   4114  C  CA   . GLY   A 1 267 ? 22.555  0.405   48.794  1.00 32.17  ?  266 GLY   B CA   1 
ATOM   4115  C  C    . GLY   A 1 267 ? 22.881  1.874   48.906  1.00 31.23  ?  266 GLY   B C    1 
ATOM   4116  O  O    . GLY   A 1 267 ? 22.184  2.644   49.557  1.00 39.04  ?  266 GLY   B O    1 
ATOM   4117  H  H    . GLY   A 1 267 ? 21.201  0.258   50.186  1.00 43.75  ?  266 GLY   B H    1 
ATOM   4118  H  HA2  . GLY   A 1 267 ? 23.229  -0.099  49.276  1.00 38.60  ?  266 GLY   B HA2  1 
ATOM   4119  H  HA3  . GLY   A 1 267 ? 22.581  0.153   47.858  1.00 38.60  ?  266 GLY   B HA3  1 
ATOM   4120  N  N    . ASN   A 1 268 ? 23.928  2.274   48.226  1.00 26.88  ?  267 ASN   B N    1 
ATOM   4121  C  CA   . ASN   A 1 268 ? 24.342  3.658   48.243  1.00 29.74  ?  267 ASN   B CA   1 
ATOM   4122  C  C    . ASN   A 1 268 ? 23.675  4.451   47.124  1.00 29.92  ?  267 ASN   B C    1 
ATOM   4123  O  O    . ASN   A 1 268 ? 23.309  3.905   46.078  1.00 29.54  ?  267 ASN   B O    1 
ATOM   4124  C  CB   . ASN   A 1 268 ? 25.861  3.742   48.077  1.00 33.53  ?  267 ASN   B CB   1 
ATOM   4125  C  CG   . ASN   A 1 268 ? 26.605  3.446   49.358  1.00 47.29  ?  267 ASN   B CG   1 
ATOM   4126  O  OD1  . ASN   A 1 268 ? 26.559  2.319   49.893  1.00 44.21  ?  267 ASN   B OD1  1 
ATOM   4127  N  ND2  . ASN   A 1 268 ? 27.320  4.461   49.856  1.00 47.39  ?  267 ASN   B ND2  1 
ATOM   4128  H  H    . ASN   A 1 268 ? 24.420  1.761   47.742  1.00 32.26  ?  267 ASN   B H    1 
ATOM   4129  H  HA   . ASN   A 1 268 ? 24.083  4.058   49.088  1.00 35.68  ?  267 ASN   B HA   1 
ATOM   4130  H  HB2  . ASN   A 1 268 ? 26.143  3.096   47.411  1.00 40.24  ?  267 ASN   B HB2  1 
ATOM   4131  H  HB3  . ASN   A 1 268 ? 26.099  4.638   47.792  1.00 40.24  ?  267 ASN   B HB3  1 
ATOM   4132  H  HD21 . ASN   A 1 268 ? 27.766  4.356   50.583  1.00 56.87  ?  267 ASN   B HD21 1 
ATOM   4133  H  HD22 . ASN   A 1 268 ? 27.333  5.218   49.448  1.00 56.87  ?  267 ASN   B HD22 1 
ATOM   4134  N  N    . TYR   A 1 269 ? 23.543  5.751   47.357  1.00 28.36  ?  268 TYR   B N    1 
ATOM   4135  C  CA   . TYR   A 1 269 ? 23.139  6.742   46.370  1.00 29.64  ?  268 TYR   B CA   1 
ATOM   4136  C  C    . TYR   A 1 269 ? 23.636  6.422   44.968  1.00 36.30  ?  268 TYR   B C    1 
ATOM   4137  O  O    . TYR   A 1 269 ? 24.824  6.243   44.748  1.00 32.55  ?  268 TYR   B O    1 
ATOM   4138  C  CB   . TYR   A 1 269 ? 23.653  8.111   46.859  1.00 32.72  ?  268 TYR   B CB   1 
ATOM   4139  C  CG   . TYR   A 1 269 ? 23.128  9.310   46.146  1.00 36.04  ?  268 TYR   B CG   1 
ATOM   4140  C  CD1  . TYR   A 1 269 ? 23.986  10.134  45.429  1.00 34.08  ?  268 TYR   B CD1  1 
ATOM   4141  C  CD2  . TYR   A 1 269 ? 21.787  9.627   46.184  1.00 29.38  ?  268 TYR   B CD2  1 
ATOM   4142  C  CE1  . TYR   A 1 269 ? 23.495  11.248  44.756  1.00 37.88  ?  268 TYR   B CE1  1 
ATOM   4143  C  CE2  . TYR   A 1 269 ? 21.310  10.733  45.555  1.00 30.88  ?  268 TYR   B CE2  1 
ATOM   4144  C  CZ   . TYR   A 1 269 ? 22.148  11.552  44.860  1.00 33.90  ?  268 TYR   B CZ   1 
ATOM   4145  O  OH   . TYR   A 1 269 ? 21.571  12.645  44.222  1.00 42.52  ?  268 TYR   B OH   1 
ATOM   4146  H  H    . TYR   A 1 269 ? 23.692  6.106   48.125  1.00 34.03  ?  268 TYR   B H    1 
ATOM   4147  H  HA   . TYR   A 1 269 ? 22.172  6.758   46.288  1.00 35.57  ?  268 TYR   B HA   1 
ATOM   4148  H  HB2  . TYR   A 1 269 ? 23.411  8.207   47.794  1.00 39.27  ?  268 TYR   B HB2  1 
ATOM   4149  H  HB3  . TYR   A 1 269 ? 24.618  8.122   46.763  1.00 39.27  ?  268 TYR   B HB3  1 
ATOM   4150  H  HD1  . TYR   A 1 269 ? 24.895  9.940   45.400  1.00 40.89  ?  268 TYR   B HD1  1 
ATOM   4151  H  HD2  . TYR   A 1 269 ? 21.200  9.074   46.647  1.00 35.25  ?  268 TYR   B HD2  1 
ATOM   4152  H  HE1  . TYR   A 1 269 ? 24.061  11.780  44.246  1.00 45.45  ?  268 TYR   B HE1  1 
ATOM   4153  H  HE2  . TYR   A 1 269 ? 20.403  10.933  45.599  1.00 37.05  ?  268 TYR   B HE2  1 
ATOM   4154  H  HH   . TYR   A 1 269 ? 22.021  12.853  43.544  1.00 51.03  ?  268 TYR   B HH   1 
ATOM   4155  N  N    . GLN   A 1 270 ? 22.716  6.307   44.024  1.00 31.31  ?  269 GLN   B N    1 
ATOM   4156  C  CA   . GLN   A 1 270 ? 22.983  6.154   42.598  1.00 34.31  ?  269 GLN   B CA   1 
ATOM   4157  C  C    . GLN   A 1 270 ? 23.607  4.830   42.207  1.00 33.39  ?  269 GLN   B C    1 
ATOM   4158  O  O    . GLN   A 1 270 ? 23.959  4.653   41.046  1.00 31.92  ?  269 GLN   B O    1 
ATOM   4159  C  CB   . GLN   A 1 270 ? 23.880  7.272   42.061  1.00 35.41  ?  269 GLN   B CB   1 
ATOM   4160  C  CG   . GLN   A 1 270 ? 23.330  8.652   42.377  1.00 42.05  ?  269 GLN   B CG   1 
ATOM   4161  C  CD   . GLN   A 1 270 ? 23.864  9.764   41.461  1.00 45.71  ?  269 GLN   B CD   1 
ATOM   4162  O  OE1  . GLN   A 1 270 ? 23.143  10.724  41.123  1.00 38.94  ?  269 GLN   B OE1  1 
ATOM   4163  N  NE2  . GLN   A 1 270 ? 25.130  9.640   41.069  1.00 46.64  ?  269 GLN   B NE2  1 
ATOM   4164  H  H    . GLN   A 1 270 ? 21.873  6.315   44.196  1.00 37.57  ?  269 GLN   B H    1 
ATOM   4165  H  HA   . GLN   A 1 270 ? 22.116  6.197   42.166  1.00 41.17  ?  269 GLN   B HA   1 
ATOM   4166  H  HB2  . GLN   A 1 270 ? 24.758  7.197   42.465  1.00 42.50  ?  269 GLN   B HB2  1 
ATOM   4167  H  HB3  . GLN   A 1 270 ? 23.950  7.188   41.097  1.00 42.50  ?  269 GLN   B HB3  1 
ATOM   4168  H  HG2  . GLN   A 1 270 ? 22.365  8.631   42.282  1.00 50.46  ?  269 GLN   B HG2  1 
ATOM   4169  H  HG3  . GLN   A 1 270 ? 23.569  8.881   43.288  1.00 50.46  ?  269 GLN   B HG3  1 
ATOM   4170  H  HE21 . GLN   A 1 270 ? 25.481  10.234  40.556  1.00 55.97  ?  269 GLN   B HE21 1 
ATOM   4171  H  HE22 . GLN   A 1 270 ? 25.597  8.966   41.329  1.00 55.97  ?  269 GLN   B HE22 1 
ATOM   4172  N  N    . CYS   A 1 271 ? 23.718  3.871   43.113  1.00 25.48  ?  270 CYS   B N    1 
ATOM   4173  C  CA   . CYS   A 1 271 ? 24.285  2.578   42.725  1.00 25.73  ?  270 CYS   B CA   1 
ATOM   4174  C  C    . CYS   A 1 271 ? 23.712  1.450   43.568  1.00 25.47  ?  270 CYS   B C    1 
ATOM   4175  O  O    . CYS   A 1 271 ? 24.385  0.439   43.809  1.00 26.29  ?  270 CYS   B O    1 
ATOM   4176  C  CB   . CYS   A 1 271 ? 25.818  2.608   42.845  1.00 32.97  ?  270 CYS   B CB   1 
ATOM   4177  S  SG   . CYS   A 1 271 ? 26.376  3.124   44.445  1.00 37.64  ?  270 CYS   B SG   1 
ATOM   4178  H  H    . CYS   A 1 271 ? 23.481  3.936   43.937  1.00 30.58  ?  270 CYS   B H    1 
ATOM   4179  H  HA   . CYS   A 1 271 ? 24.062  2.394   41.799  1.00 30.88  ?  270 CYS   B HA   1 
ATOM   4180  H  HB2  . CYS   A 1 271 ? 26.164  1.716   42.680  1.00 39.56  ?  270 CYS   B HB2  1 
ATOM   4181  H  HB3  . CYS   A 1 271 ? 26.173  3.228   42.189  1.00 39.56  ?  270 CYS   B HB3  1 
ATOM   4182  N  N    . GLY   A 1 272 ? 22.449  1.570   43.955  1.00 32.66  ?  271 GLY   B N    1 
ATOM   4183  C  CA   . GLY   A 1 272 ? 21.768  0.636   44.826  1.00 29.54  ?  271 GLY   B CA   1 
ATOM   4184  C  C    . GLY   A 1 272 ? 20.838  -0.284  44.067  1.00 30.01  ?  271 GLY   B C    1 
ATOM   4185  O  O    . GLY   A 1 272 ? 21.150  -0.782  42.963  1.00 37.01  ?  271 GLY   B O    1 
ATOM   4186  H  H    . GLY   A 1 272 ? 21.944  2.222   43.711  1.00 39.20  ?  271 GLY   B H    1 
ATOM   4187  H  HA2  . GLY   A 1 272 ? 22.424  0.093   45.291  1.00 35.45  ?  271 GLY   B HA2  1 
ATOM   4188  H  HA3  . GLY   A 1 272 ? 21.245  1.128   45.479  1.00 35.45  ?  271 GLY   B HA3  1 
ATOM   4189  N  N    . HIS   A 1 273 ? 19.689  -0.539  44.689  1.00 29.03  ?  272 HIS   B N    1 
ATOM   4190  C  CA   . HIS   A 1 273 ? 18.707  -1.472  44.148  1.00 35.51  ?  272 HIS   B CA   1 
ATOM   4191  C  C    . HIS   A 1 273 ? 17.323  -1.187  44.712  1.00 28.65  ?  272 HIS   B C    1 
ATOM   4192  O  O    . HIS   A 1 273 ? 17.164  -1.061  45.931  1.00 27.14  ?  272 HIS   B O    1 
ATOM   4193  C  CB   . HIS   A 1 273 ? 19.081  -2.919  44.465  1.00 34.63  ?  272 HIS   B CB   1 
ATOM   4194  C  CG   . HIS   A 1 273 ? 18.108  -3.931  43.938  1.00 33.17  ?  272 HIS   B CG   1 
ATOM   4195  N  ND1  . HIS   A 1 273 ? 17.933  -4.137  42.587  1.00 36.93  ?  272 HIS   B ND1  1 
ATOM   4196  C  CD2  . HIS   A 1 273 ? 17.302  -4.829  44.566  1.00 31.93  ?  272 HIS   B CD2  1 
ATOM   4197  C  CE1  . HIS   A 1 273 ? 17.042  -5.099  42.400  1.00 37.83  ?  272 HIS   B CE1  1 
ATOM   4198  N  NE2  . HIS   A 1 273 ? 16.632  -5.527  43.584  1.00 31.67  ?  272 HIS   B NE2  1 
ATOM   4199  H  H    . HIS   A 1 273 ? 19.452  -0.179  45.433  1.00 34.84  ?  272 HIS   B H    1 
ATOM   4200  H  HA   . HIS   A 1 273 ? 18.677  -1.339  43.188  1.00 42.62  ?  272 HIS   B HA   1 
ATOM   4201  H  HB2  . HIS   A 1 273 ? 19.947  -3.110  44.072  1.00 41.56  ?  272 HIS   B HB2  1 
ATOM   4202  H  HB3  . HIS   A 1 273 ? 19.124  -3.025  45.429  1.00 41.56  ?  272 HIS   B HB3  1 
ATOM   4203  H  HD2  . HIS   A 1 273 ? 17.218  -4.949  45.484  1.00 38.32  ?  272 HIS   B HD2  1 
ATOM   4204  H  HE1  . HIS   A 1 273 ? 16.752  -5.420  41.576  1.00 45.40  ?  272 HIS   B HE1  1 
ATOM   4205  H  HE2  . HIS   A 1 273 ? 16.044  -6.140  43.718  1.00 38.00  ?  272 HIS   B HE2  1 
ATOM   4206  N  N    . TYR   A 1 274 ? 16.332  -1.102  43.827  1.00 29.72  ?  273 TYR   B N    1 
ATOM   4207  C  CA   . TYR   A 1 274 ? 14.948  -0.899  44.238  1.00 26.77  ?  273 TYR   B CA   1 
ATOM   4208  C  C    . TYR   A 1 274 ? 14.199  -2.223  44.301  1.00 27.18  ?  273 TYR   B C    1 
ATOM   4209  O  O    . TYR   A 1 274 ? 14.365  -3.087  43.442  1.00 29.07  ?  273 TYR   B O    1 
ATOM   4210  C  CB   . TYR   A 1 274 ? 14.216  0.000   43.258  1.00 22.84  ?  273 TYR   B CB   1 
ATOM   4211  C  CG   . TYR   A 1 274 ? 14.504  1.466   43.357  1.00 27.06  ?  273 TYR   B CG   1 
ATOM   4212  C  CD1  . TYR   A 1 274 ? 15.435  2.078   42.496  1.00 22.12  ?  273 TYR   B CD1  1 
ATOM   4213  C  CD2  . TYR   A 1 274 ? 13.784  2.268   44.253  1.00 23.02  ?  273 TYR   B CD2  1 
ATOM   4214  C  CE1  . TYR   A 1 274 ? 15.634  3.441   42.529  1.00 20.12  ?  273 TYR   B CE1  1 
ATOM   4215  C  CE2  . TYR   A 1 274 ? 13.981  3.644   44.296  1.00 24.62  ?  273 TYR   B CE2  1 
ATOM   4216  C  CZ   . TYR   A 1 274 ? 14.930  4.236   43.454  1.00 27.16  ?  273 TYR   B CZ   1 
ATOM   4217  O  OH   . TYR   A 1 274 ? 15.112  5.623   43.491  1.00 25.89  ?  273 TYR   B OH   1 
ATOM   4218  H  H    . TYR   A 1 274 ? 16.440  -1.160  42.976  1.00 35.66  ?  273 TYR   B H    1 
ATOM   4219  H  HA   . TYR   A 1 274 ? 14.954  -0.492  45.118  1.00 32.12  ?  273 TYR   B HA   1 
ATOM   4220  H  HB2  . TYR   A 1 274 ? 14.453  -0.276  42.360  1.00 27.41  ?  273 TYR   B HB2  1 
ATOM   4221  H  HB3  . TYR   A 1 274 ? 13.263  -0.113  43.400  1.00 27.41  ?  273 TYR   B HB3  1 
ATOM   4222  H  HD1  . TYR   A 1 274 ? 15.920  1.557   41.898  1.00 26.55  ?  273 TYR   B HD1  1 
ATOM   4223  H  HD2  . TYR   A 1 274 ? 13.166  1.875   44.826  1.00 27.63  ?  273 TYR   B HD2  1 
ATOM   4224  H  HE1  . TYR   A 1 274 ? 16.235  3.837   41.940  1.00 24.14  ?  273 TYR   B HE1  1 
ATOM   4225  H  HE2  . TYR   A 1 274 ? 13.484  4.169   44.881  1.00 29.54  ?  273 TYR   B HE2  1 
ATOM   4226  H  HH   . TYR   A 1 274 ? 14.479  5.985   43.907  1.00 31.07  ?  273 TYR   B HH   1 
ATOM   4227  N  N    . LYS   A 1 275 ? 13.326  -2.353  45.285  1.00 31.74  ?  274 LYS   B N    1 
ATOM   4228  C  CA   . LYS   A 1 275 ? 12.215  -3.280  45.230  1.00 30.33  ?  274 LYS   B CA   1 
ATOM   4229  C  C    . LYS   A 1 275 ? 10.908  -2.517  45.487  1.00 36.19  ?  274 LYS   B C    1 
ATOM   4230  O  O    . LYS   A 1 275 ? 10.899  -1.368  45.936  1.00 34.91  ?  274 LYS   B O    1 
ATOM   4231  C  CB   . LYS   A 1 275 ? 12.402  -4.386  46.255  1.00 34.73  ?  274 LYS   B CB   1 
ATOM   4232  C  CG   . LYS   A 1 275 ? 13.727  -5.098  46.258  1.00 34.45  ?  274 LYS   B CG   1 
ATOM   4233  C  CD   . LYS   A 1 275 ? 13.653  -6.208  47.355  1.00 37.23  ?  274 LYS   B CD   1 
ATOM   4234  C  CE   . LYS   A 1 275 ? 14.921  -7.037  47.422  1.00 34.33  ?  274 LYS   B CE   1 
ATOM   4235  N  NZ   . LYS   A 1 275 ? 15.268  -7.345  48.838  1.00 46.97  ?  274 LYS   B NZ   1 
ATOM   4236  H  H    . LYS   A 1 275 ? 13.359  -1.900  46.015  1.00 38.09  ?  274 LYS   B H    1 
ATOM   4237  H  HA   . LYS   A 1 275 ? 12.158  -3.686  44.351  1.00 36.40  ?  274 LYS   B HA   1 
ATOM   4238  H  HB2  . LYS   A 1 275 ? 12.287  -4.000  47.137  1.00 41.68  ?  274 LYS   B HB2  1 
ATOM   4239  H  HB3  . LYS   A 1 275 ? 11.721  -5.059  46.096  1.00 41.68  ?  274 LYS   B HB3  1 
ATOM   4240  H  HG2  . LYS   A 1 275 ? 13.893  -5.508  45.394  1.00 41.34  ?  274 LYS   B HG2  1 
ATOM   4241  H  HG3  . LYS   A 1 275 ? 14.442  -4.479  46.473  1.00 41.34  ?  274 LYS   B HG3  1 
ATOM   4242  H  HD2  . LYS   A 1 275 ? 13.518  -5.791  48.220  1.00 44.68  ?  274 LYS   B HD2  1 
ATOM   4243  H  HD3  . LYS   A 1 275 ? 12.913  -6.803  47.155  1.00 44.68  ?  274 LYS   B HD3  1 
ATOM   4244  H  HE2  . LYS   A 1 275 ? 14.789  -7.873  46.947  1.00 41.19  ?  274 LYS   B HE2  1 
ATOM   4245  H  HE3  . LYS   A 1 275 ? 15.655  -6.542  47.025  1.00 41.19  ?  274 LYS   B HE3  1 
ATOM   4246  H  HZ1  . LYS   A 1 275 ? 16.036  -7.794  48.873  1.00 56.37  ?  274 LYS   B HZ1  1 
ATOM   4247  H  HZ2  . LYS   A 1 275 ? 15.354  -6.590  49.301  1.00 56.37  ?  274 LYS   B HZ2  1 
ATOM   4248  H  HZ3  . LYS   A 1 275 ? 14.627  -7.839  49.208  1.00 56.37  ?  274 LYS   B HZ3  1 
ATOM   4249  N  N    . HIS   A 1 276 ? 9.792   -3.176  45.202  1.00 33.85  ?  275 HIS   B N    1 
ATOM   4250  C  CA   . HIS   A 1 276 ? 8.469   -2.563  45.164  1.00 33.95  ?  275 HIS   B CA   1 
ATOM   4251  C  C    . HIS   A 1 276 ? 7.593   -3.298  46.155  1.00 30.27  ?  275 HIS   B C    1 
ATOM   4252  O  O    . HIS   A 1 276 ? 7.432   -4.511  46.047  1.00 34.03  ?  275 HIS   B O    1 
ATOM   4253  C  CB   . HIS   A 1 276 ? 7.874   -2.646  43.764  1.00 32.91  ?  275 HIS   B CB   1 
ATOM   4254  C  CG   . HIS   A 1 276 ? 6.461   -2.153  43.666  1.00 32.58  ?  275 HIS   B CG   1 
ATOM   4255  N  ND1  . HIS   A 1 276 ? 6.153   -0.824  43.480  1.00 36.28  ?  275 HIS   B ND1  1 
ATOM   4256  C  CD2  . HIS   A 1 276 ? 5.273   -2.819  43.682  1.00 36.37  ?  275 HIS   B CD2  1 
ATOM   4257  C  CE1  . HIS   A 1 276 ? 4.833   -0.694  43.373  1.00 37.07  ?  275 HIS   B CE1  1 
ATOM   4258  N  NE2  . HIS   A 1 276 ? 4.279   -1.888  43.488  1.00 31.66  ?  275 HIS   B NE2  1 
ATOM   4259  H  H    . HIS   A 1 276 ? 9.774   -4.016  45.019  1.00 40.62  ?  275 HIS   B H    1 
ATOM   4260  H  HA   . HIS   A 1 276 ? 8.523   -1.629  45.418  1.00 40.74  ?  275 HIS   B HA   1 
ATOM   4261  H  HB2  . HIS   A 1 276 ? 8.415   -2.109  43.164  1.00 39.49  ?  275 HIS   B HB2  1 
ATOM   4262  H  HB3  . HIS   A 1 276 ? 7.882   -3.573  43.478  1.00 39.49  ?  275 HIS   B HB3  1 
ATOM   4263  H  HD1  . HIS   A 1 276 ? 6.723   -0.181  43.439  1.00 43.54  ?  275 HIS   B HD1  1 
ATOM   4264  H  HD2  . HIS   A 1 276 ? 5.155   -3.734  43.801  1.00 43.65  ?  275 HIS   B HD2  1 
ATOM   4265  H  HE1  . HIS   A 1 276 ? 4.376   0.105   43.239  1.00 44.48  ?  275 HIS   B HE1  1 
ATOM   4266  N  N    . ILE   A 1 277 ? 7.016   -2.569  47.098  1.00 28.41  ?  276 ILE   B N    1 
ATOM   4267  C  CA   . ILE   A 1 277 ? 6.147   -3.147  48.126  1.00 34.49  ?  276 ILE   B CA   1 
ATOM   4268  C  C    . ILE   A 1 277 ? 4.713   -2.693  47.873  1.00 36.32  ?  276 ILE   B C    1 
ATOM   4269  O  O    . ILE   A 1 277 ? 4.450   -1.493  47.771  1.00 28.92  ?  276 ILE   B O    1 
ATOM   4270  C  CB   . ILE   A 1 277 ? 6.597   -2.750  49.535  1.00 38.39  ?  276 ILE   B CB   1 
ATOM   4271  C  CG1  . ILE   A 1 277 ? 7.910   -3.447  49.859  1.00 45.52  ?  276 ILE   B CG1  1 
ATOM   4272  C  CG2  . ILE   A 1 277 ? 5.561   -3.152  50.535  1.00 40.22  ?  276 ILE   B CG2  1 
ATOM   4273  C  CD1  . ILE   A 1 277 ? 9.058   -2.758  49.264  1.00 42.32  ?  276 ILE   B CD1  1 
ATOM   4274  H  H    . ILE   A 1 277 ? 7.111   -1.717  47.169  1.00 34.09  ?  276 ILE   B H    1 
ATOM   4275  H  HA   . ILE   A 1 277 ? 6.176   -4.114  48.047  1.00 41.39  ?  276 ILE   B HA   1 
ATOM   4276  H  HB   . ILE   A 1 277 ? 6.718   -1.788  49.569  1.00 46.07  ?  276 ILE   B HB   1 
ATOM   4277  H  HG12 . ILE   A 1 277 ? 8.032   -3.466  50.821  1.00 54.63  ?  276 ILE   B HG12 1 
ATOM   4278  H  HG13 . ILE   A 1 277 ? 7.885   -4.352  49.511  1.00 54.63  ?  276 ILE   B HG13 1 
ATOM   4279  H  HG21 . ILE   A 1 277 ? 5.909   -3.002  51.428  1.00 48.26  ?  276 ILE   B HG21 1 
ATOM   4280  H  HG22 . ILE   A 1 277 ? 4.764   -2.617  50.396  1.00 48.26  ?  276 ILE   B HG22 1 
ATOM   4281  H  HG23 . ILE   A 1 277 ? 5.354   -4.092  50.414  1.00 48.26  ?  276 ILE   B HG23 1 
ATOM   4282  H  HD11 . ILE   A 1 277 ? 9.875   -3.177  49.576  1.00 50.79  ?  276 ILE   B HD11 1 
ATOM   4283  H  HD12 . ILE   A 1 277 ? 9.000   -2.824  48.298  1.00 50.79  ?  276 ILE   B HD12 1 
ATOM   4284  H  HD13 . ILE   A 1 277 ? 9.041   -1.826  49.533  1.00 50.79  ?  276 ILE   B HD13 1 
ATOM   4285  N  N    . THR   A 1 278 ? 3.803   -3.650  47.729  1.00 34.29  ?  277 THR   B N    1 
ATOM   4286  C  CA   . THR   A 1 278 ? 2.403   -3.379  47.471  1.00 34.55  ?  277 THR   B CA   1 
ATOM   4287  C  C    . THR   A 1 278 ? 1.515   -3.961  48.576  1.00 36.53  ?  277 THR   B C    1 
ATOM   4288  O  O    . THR   A 1 278 ? 1.783   -5.030  49.136  1.00 37.23  ?  277 THR   B O    1 
ATOM   4289  C  CB   . THR   A 1 278 ? 1.994   -3.940  46.102  1.00 36.76  ?  277 THR   B CB   1 
ATOM   4290  O  OG1  . THR   A 1 278 ? 0.643   -3.556  45.821  1.00 42.74  ?  277 THR   B OG1  1 
ATOM   4291  C  CG2  . THR   A 1 278 ? 2.083   -5.446  46.132  1.00 39.11  ?  277 THR   B CG2  1 
ATOM   4292  H  H    . THR   A 1 278 ? 3.982   -4.490  47.780  1.00 41.15  ?  277 THR   B H    1 
ATOM   4293  H  HA   . THR   A 1 278 ? 2.252   -2.420  47.473  1.00 41.46  ?  277 THR   B HA   1 
ATOM   4294  H  HB   . THR   A 1 278 ? 2.579   -3.600  45.407  1.00 44.12  ?  277 THR   B HB   1 
ATOM   4295  H  HG1  . THR   A 1 278 ? 0.151   -4.236  45.789  1.00 51.29  ?  277 THR   B HG1  1 
ATOM   4296  H  HG21 . THR   A 1 278 ? 1.890   -5.808  45.253  1.00 46.93  ?  277 THR   B HG21 1 
ATOM   4297  H  HG22 . THR   A 1 278 ? 2.975   -5.721  46.396  1.00 46.93  ?  277 THR   B HG22 1 
ATOM   4298  H  HG23 . THR   A 1 278 ? 1.443   -5.804  46.767  1.00 46.93  ?  277 THR   B HG23 1 
ATOM   4299  N  N    . SER   A 1 279 ? 0.446   -3.243  48.878  1.00 38.24  ?  278 SER   B N    1 
ATOM   4300  C  CA   . SER   A 1 279 ? -0.552  -3.649  49.871  1.00 40.69  ?  278 SER   B CA   1 
ATOM   4301  C  C    . SER   A 1 279 ? -1.846  -4.110  49.187  1.00 41.42  ?  278 SER   B C    1 
ATOM   4302  O  O    . SER   A 1 279 ? -2.611  -3.288  48.655  1.00 31.75  ?  278 SER   B O    1 
ATOM   4303  C  CB   . SER   A 1 279 ? -0.837  -2.480  50.815  1.00 35.83  ?  278 SER   B CB   1 
ATOM   4304  O  OG   . SER   A 1 279 ? -1.638  -2.874  51.884  1.00 35.37  ?  278 SER   B OG   1 
ATOM   4305  H  H    . SER   A 1 279 ? 0.264   -2.488  48.510  1.00 45.89  ?  278 SER   B H    1 
ATOM   4306  H  HA   . SER   A 1 279 ? -0.205  -4.411  50.361  1.00 48.83  ?  278 SER   B HA   1 
ATOM   4307  H  HB2  . SER   A 1 279 ? 0.005   -2.144  51.161  1.00 43.00  ?  278 SER   B HB2  1 
ATOM   4308  H  HB3  . SER   A 1 279 ? -1.294  -1.782  50.321  1.00 43.00  ?  278 SER   B HB3  1 
ATOM   4309  H  HG   . SER   A 1 279 ? -1.194  -3.349  52.416  1.00 42.44  ?  278 SER   B HG   1 
ATOM   4310  N  N    . LYS   A 1 280 ? -2.103  -5.430  49.245  1.00 41.76  ?  279 LYS   B N    1 
ATOM   4311  C  CA   . LYS   A 1 280 ? -3.294  -6.031  48.697  1.00 47.74  ?  279 LYS   B CA   1 
ATOM   4312  C  C    . LYS   A 1 280 ? -4.063  -6.681  49.870  1.00 49.09  ?  279 LYS   B C    1 
ATOM   4313  O  O    . LYS   A 1 280 ? -4.476  -5.981  50.779  1.00 42.41  ?  279 LYS   B O    1 
ATOM   4314  C  CB   . LYS   A 1 280 ? -2.948  -6.968  47.529  1.00 40.34  ?  279 LYS   B CB   1 
ATOM   4315  C  CG   . LYS   A 1 280 ? -2.306  -6.199  46.386  1.00 46.59  ?  279 LYS   B CG   1 
ATOM   4316  C  CD   . LYS   A 1 280 ? -2.736  -6.727  45.050  1.00 41.45  ?  279 LYS   B CD   1 
ATOM   4317  C  CE   . LYS   A 1 280 ? -2.033  -5.958  43.937  1.00 41.09  ?  279 LYS   B CE   1 
ATOM   4318  N  NZ   . LYS   A 1 280 ? -2.210  -6.685  42.641  1.00 40.09  ?  279 LYS   B NZ   1 
ATOM   4319  H  H    . LYS   A 1 280 ? -1.576  -6.002  49.611  1.00 50.11  ?  279 LYS   B H    1 
ATOM   4320  H  HA   . LYS   A 1 280 ? -3.852  -5.323  48.339  1.00 57.29  ?  279 LYS   B HA   1 
ATOM   4321  H  HB2  . LYS   A 1 280 ? -2.325  -7.646  47.834  1.00 48.41  ?  279 LYS   B HB2  1 
ATOM   4322  H  HB3  . LYS   A 1 280 ? -3.760  -7.387  47.201  1.00 48.41  ?  279 LYS   B HB3  1 
ATOM   4323  H  HG2  . LYS   A 1 280 ? -2.565  -5.266  46.441  1.00 55.90  ?  279 LYS   B HG2  1 
ATOM   4324  H  HG3  . LYS   A 1 280 ? -1.341  -6.279  46.448  1.00 55.90  ?  279 LYS   B HG3  1 
ATOM   4325  H  HD2  . LYS   A 1 280 ? -2.500  -7.665  44.978  1.00 49.74  ?  279 LYS   B HD2  1 
ATOM   4326  H  HD3  . LYS   A 1 280 ? -3.694  -6.618  44.948  1.00 49.74  ?  279 LYS   B HD3  1 
ATOM   4327  H  HE2  . LYS   A 1 280 ? -2.420  -5.072  43.855  1.00 49.31  ?  279 LYS   B HE2  1 
ATOM   4328  H  HE3  . LYS   A 1 280 ? -1.086  -5.890  44.132  1.00 49.31  ?  279 LYS   B HE3  1 
ATOM   4329  H  HZ1  . LYS   A 1 280 ? -1.539  -7.257  42.519  1.00 48.10  ?  279 LYS   B HZ1  1 
ATOM   4330  H  HZ2  . LYS   A 1 280 ? -2.977  -7.137  42.648  1.00 48.10  ?  279 LYS   B HZ2  1 
ATOM   4331  H  HZ3  . LYS   A 1 280 ? -2.222  -6.105  41.966  1.00 48.10  ?  279 LYS   B HZ3  1 
ATOM   4332  N  N    . GLU   A 1 281 ? -4.265  -8.006  49.828  1.00 47.08  ?  280 GLU   B N    1 
ATOM   4333  C  CA   . GLU   A 1 281 ? -4.783  -8.722  50.988  1.00 44.08  ?  280 GLU   B CA   1 
ATOM   4334  C  C    . GLU   A 1 281 ? -3.714  -8.917  52.060  1.00 45.32  ?  280 GLU   B C    1 
ATOM   4335  O  O    . GLU   A 1 281 ? -4.040  -9.155  53.233  1.00 46.33  ?  280 GLU   B O    1 
ATOM   4336  C  CB   . GLU   A 1 281 ? -5.349  -10.086 50.566  1.00 42.44  ?  280 GLU   B CB   1 
ATOM   4337  C  CG   . GLU   A 1 281 ? -4.320  -11.209 50.524  1.00 52.61  ?  280 GLU   B CG   1 
ATOM   4338  C  CD   . GLU   A 1 281 ? -3.715  -11.402 49.127  1.00 51.85  ?  280 GLU   B CD   1 
ATOM   4339  O  OE1  . GLU   A 1 281 ? -3.485  -12.565 48.711  1.00 55.18  ?  280 GLU   B OE1  1 
ATOM   4340  O  OE2  . GLU   A 1 281 ? -3.482  -10.388 48.431  1.00 51.88  -1 280 GLU   B OE2  1 
ATOM   4341  H  H    . GLU   A 1 281 ? -4.109  -8.503  49.144  1.00 56.50  ?  280 GLU   B H    1 
ATOM   4342  H  HA   . GLU   A 1 281 ? -5.513  -8.213  51.373  1.00 52.89  ?  280 GLU   B HA   1 
ATOM   4343  H  HB2  . GLU   A 1 281 ? -6.039  -10.344 51.198  1.00 50.92  ?  280 GLU   B HB2  1 
ATOM   4344  H  HB3  . GLU   A 1 281 ? -5.729  -10.002 49.678  1.00 50.92  ?  280 GLU   B HB3  1 
ATOM   4345  H  HG2  . GLU   A 1 281 ? -3.599  -11.001 51.138  1.00 63.13  ?  280 GLU   B HG2  1 
ATOM   4346  H  HG3  . GLU   A 1 281 ? -4.748  -12.040 50.784  1.00 63.13  ?  280 GLU   B HG3  1 
ATOM   4347  N  N    . THR   A 1 282 ? -2.443  -8.902  51.663  1.00 52.42  ?  281 THR   B N    1 
ATOM   4348  C  CA   . THR   A 1 282 ? -1.312  -8.915  52.582  1.00 41.40  ?  281 THR   B CA   1 
ATOM   4349  C  C    . THR   A 1 282 ? -0.243  -8.029  51.954  1.00 42.41  ?  281 THR   B C    1 
ATOM   4350  O  O    . THR   A 1 282 ? -0.447  -7.459  50.877  1.00 40.11  ?  281 THR   B O    1 
ATOM   4351  C  CB   . THR   A 1 282 ? -0.835  -10.340 52.868  1.00 34.10  ?  281 THR   B CB   1 
ATOM   4352  O  OG1  . THR   A 1 282 ? 0.017   -10.313 54.014  1.00 47.23  ?  281 THR   B OG1  1 
ATOM   4353  C  CG2  . THR   A 1 282 ? -0.105  -10.920 51.696  1.00 53.20  ?  281 THR   B CG2  1 
ATOM   4354  H  H    . THR   A 1 282 ? -2.204  -8.882  50.837  1.00 62.90  ?  281 THR   B H    1 
ATOM   4355  H  HA   . THR   A 1 282 ? -1.554  -8.544  53.445  1.00 49.68  ?  281 THR   B HA   1 
ATOM   4356  H  HB   . THR   A 1 282 ? -1.598  -10.915 53.036  1.00 40.92  ?  281 THR   B HB   1 
ATOM   4357  H  HG1  . THR   A 1 282 ? 0.365   -11.069 54.131  1.00 56.68  ?  281 THR   B HG1  1 
ATOM   4358  H  HG21 . THR   A 1 282 ? 0.137   -11.842 51.878  1.00 63.84  ?  281 THR   B HG21 1 
ATOM   4359  H  HG22 . THR   A 1 282 ? -0.669  -10.893 50.907  1.00 63.84  ?  281 THR   B HG22 1 
ATOM   4360  H  HG23 . THR   A 1 282 ? 0.702   -10.411 51.523  1.00 63.84  ?  281 THR   B HG23 1 
ATOM   4361  N  N    . LEU   A 1 283 ? 0.876   -7.857  52.647  1.00 43.24  ?  282 LEU   B N    1 
ATOM   4362  C  CA   . LEU   A 1 283 ? 1.987   -7.092  52.100  1.00 43.42  ?  282 LEU   B CA   1 
ATOM   4363  C  C    . LEU   A 1 283 ? 2.816   -7.969  51.183  1.00 38.31  ?  282 LEU   B C    1 
ATOM   4364  O  O    . LEU   A 1 283 ? 3.257   -9.054  51.573  1.00 46.67  ?  282 LEU   B O    1 
ATOM   4365  C  CB   . LEU   A 1 283 ? 2.869   -6.551  53.201  1.00 33.70  ?  282 LEU   B CB   1 
ATOM   4366  C  CG   . LEU   A 1 283 ? 2.174   -5.565  54.113  1.00 43.86  ?  282 LEU   B CG   1 
ATOM   4367  C  CD1  . LEU   A 1 283 ? 3.152   -5.055  55.163  1.00 42.87  ?  282 LEU   B CD1  1 
ATOM   4368  C  CD2  . LEU   A 1 283 ? 1.585   -4.434  53.297  1.00 45.56  ?  282 LEU   B CD2  1 
ATOM   4369  H  H    . LEU   A 1 283 ? 1.016   -8.173  53.435  1.00 51.89  ?  282 LEU   B H    1 
ATOM   4370  H  HA   . LEU   A 1 283 ? 1.630   -6.343  51.597  1.00 52.11  ?  282 LEU   B HA   1 
ATOM   4371  H  HB2  . LEU   A 1 283 ? 3.177   -7.292  53.745  1.00 40.44  ?  282 LEU   B HB2  1 
ATOM   4372  H  HB3  . LEU   A 1 283 ? 3.626   -6.098  52.798  1.00 40.44  ?  282 LEU   B HB3  1 
ATOM   4373  H  HG   . LEU   A 1 283 ? 1.443   -5.997  54.582  1.00 52.63  ?  282 LEU   B HG   1 
ATOM   4374  H  HD11 . LEU   A 1 283 ? 2.657   -4.599  55.861  1.00 51.44  ?  282 LEU   B HD11 1 
ATOM   4375  H  HD12 . LEU   A 1 283 ? 3.634   -5.809  55.538  1.00 51.44  ?  282 LEU   B HD12 1 
ATOM   4376  H  HD13 . LEU   A 1 283 ? 3.774   -4.441  54.743  1.00 51.44  ?  282 LEU   B HD13 1 
ATOM   4377  H  HD21 . LEU   A 1 283 ? 1.506   -3.648  53.859  1.00 54.67  ?  282 LEU   B HD21 1 
ATOM   4378  H  HD22 . LEU   A 1 283 ? 2.172   -4.248  52.547  1.00 54.67  ?  282 LEU   B HD22 1 
ATOM   4379  H  HD23 . LEU   A 1 283 ? 0.710   -4.700  52.975  1.00 54.67  ?  282 LEU   B HD23 1 
ATOM   4380  N  N    . TYR   A 1 284 ? 2.986   -7.528  49.953  1.00 33.39  ?  283 TYR   B N    1 
ATOM   4381  C  CA   . TYR   A 1 284 ? 3.842   -8.228  49.016  1.00 37.35  ?  283 TYR   B CA   1 
ATOM   4382  C  C    . TYR   A 1 284 ? 5.119   -7.426  48.737  1.00 38.60  ?  283 TYR   B C    1 
ATOM   4383  O  O    . TYR   A 1 284 ? 5.154   -6.197  48.824  1.00 37.05  ?  283 TYR   B O    1 
ATOM   4384  C  CB   . TYR   A 1 284 ? 3.106   -8.482  47.716  1.00 34.57  ?  283 TYR   B CB   1 
ATOM   4385  C  CG   . TYR   A 1 284 ? 2.066   -9.570  47.715  1.00 43.65  ?  283 TYR   B CG   1 
ATOM   4386  C  CD1  . TYR   A 1 284 ? 0.740   -9.286  47.983  1.00 44.40  ?  283 TYR   B CD1  1 
ATOM   4387  C  CD2  . TYR   A 1 284 ? 2.402   -10.874 47.377  1.00 44.82  ?  283 TYR   B CD2  1 
ATOM   4388  C  CE1  . TYR   A 1 284 ? -0.225  -10.282 47.928  1.00 49.41  ?  283 TYR   B CE1  1 
ATOM   4389  C  CE2  . TYR   A 1 284 ? 1.444   -11.867 47.297  1.00 51.84  ?  283 TYR   B CE2  1 
ATOM   4390  C  CZ   . TYR   A 1 284 ? 0.131   -11.568 47.597  1.00 51.18  ?  283 TYR   B CZ   1 
ATOM   4391  O  OH   . TYR   A 1 284 ? -0.828  -12.553 47.558  1.00 47.45  ?  283 TYR   B OH   1 
ATOM   4392  H  H    . TYR   A 1 284 ? 2.615   -6.820  49.636  1.00 40.07  ?  283 TYR   B H    1 
ATOM   4393  H  HA   . TYR   A 1 284 ? 4.108   -9.078  49.398  1.00 44.82  ?  283 TYR   B HA   1 
ATOM   4394  H  HB2  . TYR   A 1 284 ? 2.655   -7.661  47.463  1.00 41.49  ?  283 TYR   B HB2  1 
ATOM   4395  H  HB3  . TYR   A 1 284 ? 3.763   -8.720  47.043  1.00 41.49  ?  283 TYR   B HB3  1 
ATOM   4396  H  HD1  . TYR   A 1 284 ? 0.491   -8.417  48.202  1.00 53.28  ?  283 TYR   B HD1  1 
ATOM   4397  H  HD2  . TYR   A 1 284 ? 3.291   -11.084 47.200  1.00 53.78  ?  283 TYR   B HD2  1 
ATOM   4398  H  HE1  . TYR   A 1 284 ? -1.113  -10.079 48.116  1.00 59.29  ?  283 TYR   B HE1  1 
ATOM   4399  H  HE2  . TYR   A 1 284 ? 1.683   -12.729 47.044  1.00 62.21  ?  283 TYR   B HE2  1 
ATOM   4400  H  HH   . TYR   A 1 284 ? -0.471  -13.295 47.391  1.00 56.94  ?  283 TYR   B HH   1 
ATOM   4401  N  N    . CYS   A 1 285 ? 6.175   -8.135  48.401  1.00 37.30  ?  284 CYS   B N    1 
ATOM   4402  C  CA   . CYS   A 1 285 ? 7.408   -7.535  47.903  1.00 39.71  ?  284 CYS   B CA   1 
ATOM   4403  C  C    . CYS   A 1 285 ? 7.716   -8.097  46.512  1.00 37.00  ?  284 CYS   B C    1 
ATOM   4404  O  O    . CYS   A 1 285 ? 7.969   -9.302  46.367  1.00 31.41  ?  284 CYS   B O    1 
ATOM   4405  C  CB   . CYS   A 1 285 ? 8.560   -7.793  48.860  1.00 39.93  ?  284 CYS   B CB   1 
ATOM   4406  S  SG   . CYS   A 1 285 ? 10.133  -7.191  48.154  1.00 42.06  ?  284 CYS   B SG   1 
ATOM   4407  H  H    . CYS   A 1 285 ? 6.209   -8.993  48.451  1.00 44.77  ?  284 CYS   B H    1 
ATOM   4408  H  HA   . CYS   A 1 285 ? 7.280   -6.578  47.815  1.00 47.66  ?  284 CYS   B HA   1 
ATOM   4409  H  HB2  . CYS   A 1 285 ? 8.397   -7.327  49.695  1.00 47.92  ?  284 CYS   B HB2  1 
ATOM   4410  H  HB3  . CYS   A 1 285 ? 8.638   -8.747  49.022  1.00 47.92  ?  284 CYS   B HB3  1 
ATOM   4411  H  HG   . CYS   A 1 285 ? 10.984  -7.239  48.999  1.00 50.47  ?  284 CYS   B HG   1 
ATOM   4412  N  N    . ILE   A 1 286 ? 7.625   -7.238  45.491  1.00 32.65  ?  285 ILE   B N    1 
ATOM   4413  C  CA   . ILE   A 1 286 ? 7.907   -7.621  44.112  1.00 38.05  ?  285 ILE   B CA   1 
ATOM   4414  C  C    . ILE   A 1 286 ? 9.279   -7.075  43.721  1.00 29.87  ?  285 ILE   B C    1 
ATOM   4415  O  O    . ILE   A 1 286 ? 9.482   -5.861  43.602  1.00 26.11  ?  285 ILE   B O    1 
ATOM   4416  C  CB   . ILE   A 1 286 ? 6.836   -7.127  43.133  1.00 35.55  ?  285 ILE   B CB   1 
ATOM   4417  C  CG1  . ILE   A 1 286 ? 5.461   -7.640  43.530  1.00 42.25  ?  285 ILE   B CG1  1 
ATOM   4418  C  CG2  . ILE   A 1 286 ? 7.209   -7.572  41.725  1.00 30.69  ?  285 ILE   B CG2  1 
ATOM   4419  C  CD1  . ILE   A 1 286 ? 4.340   -7.020  42.706  1.00 39.37  ?  285 ILE   B CD1  1 
ATOM   4420  H  H    . ILE   A 1 286 ? 7.397   -6.413  45.579  1.00 39.17  ?  285 ILE   B H    1 
ATOM   4421  H  HA   . ILE   A 1 286 ? 7.937   -8.590  44.079  1.00 45.66  ?  285 ILE   B HA   1 
ATOM   4422  H  HB   . ILE   A 1 286 ? 6.799   -6.158  43.161  1.00 42.66  ?  285 ILE   B HB   1 
ATOM   4423  H  HG12 . ILE   A 1 286 ? 5.432   -8.600  43.400  1.00 50.70  ?  285 ILE   B HG12 1 
ATOM   4424  H  HG13 . ILE   A 1 286 ? 5.301   -7.426  44.463  1.00 50.70  ?  285 ILE   B HG13 1 
ATOM   4425  H  HG21 . ILE   A 1 286 ? 6.464   -7.395  41.130  1.00 36.82  ?  285 ILE   B HG21 1 
ATOM   4426  H  HG22 . ILE   A 1 286 ? 7.990   -7.077  41.433  1.00 36.82  ?  285 ILE   B HG22 1 
ATOM   4427  H  HG23 . ILE   A 1 286 ? 7.404   -8.522  41.736  1.00 36.82  ?  285 ILE   B HG23 1 
ATOM   4428  H  HD11 . ILE   A 1 286 ? 3.500   -7.139  43.175  1.00 47.24  ?  285 ILE   B HD11 1 
ATOM   4429  H  HD12 . ILE   A 1 286 ? 4.522   -6.074  42.588  1.00 47.24  ?  285 ILE   B HD12 1 
ATOM   4430  H  HD13 . ILE   A 1 286 ? 4.303   -7.460  41.843  1.00 47.24  ?  285 ILE   B HD13 1 
ATOM   4431  N  N    . ASP   A 1 287 ? 10.200  -7.981  43.496  1.00 32.60  ?  286 ASP   B N    1 
ATOM   4432  C  CA   . ASP   A 1 287 ? 11.578  -7.672  43.147  1.00 27.25  ?  286 ASP   B CA   1 
ATOM   4433  C  C    . ASP   A 1 287 ? 11.782  -8.202  41.734  1.00 30.68  ?  286 ASP   B C    1 
ATOM   4434  O  O    . ASP   A 1 287 ? 12.242  -9.339  41.547  1.00 29.08  ?  286 ASP   B O    1 
ATOM   4435  C  CB   . ASP   A 1 287 ? 12.505  -8.328  44.173  1.00 35.60  ?  286 ASP   B CB   1 
ATOM   4436  C  CG   . ASP   A 1 287 ? 13.962  -8.093  43.888  1.00 39.81  ?  286 ASP   B CG   1 
ATOM   4437  O  OD1  . ASP   A 1 287 ? 14.317  -7.367  42.911  1.00 34.79  ?  286 ASP   B OD1  1 
ATOM   4438  O  OD2  . ASP   A 1 287 ? 14.740  -8.662  44.672  1.00 39.07  -1 286 ASP   B OD2  1 
ATOM   4439  H  H    . ASP   A 1 287 ? 10.051  -8.826  43.540  1.00 39.12  ?  286 ASP   B H    1 
ATOM   4440  H  HA   . ASP   A 1 287 ? 11.755  -6.718  43.139  1.00 32.70  ?  286 ASP   B HA   1 
ATOM   4441  H  HB2  . ASP   A 1 287 ? 12.311  -7.964  45.051  1.00 42.72  ?  286 ASP   B HB2  1 
ATOM   4442  H  HB3  . ASP   A 1 287 ? 12.351  -9.285  44.169  1.00 42.72  ?  286 ASP   B HB3  1 
ATOM   4443  N  N    . GLY   A 1 288 ? 11.427  -7.372  40.741  1.00 27.84  ?  287 GLY   B N    1 
ATOM   4444  C  CA   . GLY   A 1 288 ? 11.526  -7.765  39.353  1.00 26.76  ?  287 GLY   B CA   1 
ATOM   4445  C  C    . GLY   A 1 288 ? 10.679  -8.988  39.131  1.00 28.07  ?  287 GLY   B C    1 
ATOM   4446  O  O    . GLY   A 1 288 ? 9.453   -8.913  39.192  1.00 35.46  ?  287 GLY   B O    1 
ATOM   4447  H  H    . GLY   A 1 288 ? 11.127  -6.574  40.859  1.00 33.40  ?  287 GLY   B H    1 
ATOM   4448  H  HA2  . GLY   A 1 288 ? 11.211  -7.049  38.780  1.00 32.11  ?  287 GLY   B HA2  1 
ATOM   4449  H  HA3  . GLY   A 1 288 ? 12.447  -7.968  39.128  1.00 32.11  ?  287 GLY   B HA3  1 
ATOM   4450  N  N    . ALA   A 1 289 ? 11.313  -10.118 38.917  1.00 29.45  ?  288 ALA   B N    1 
ATOM   4451  C  CA   . ALA   A 1 289 ? 10.631  -11.369 38.628  1.00 32.42  ?  288 ALA   B CA   1 
ATOM   4452  C  C    . ALA   A 1 289 ? 10.410  -12.226 39.855  1.00 34.71  ?  288 ALA   B C    1 
ATOM   4453  O  O    . ALA   A 1 289 ? 9.929   -13.351 39.725  1.00 39.25  ?  288 ALA   B O    1 
ATOM   4454  C  CB   . ALA   A 1 289 ? 11.433  -12.207 37.611  1.00 31.07  ?  288 ALA   B CB   1 
ATOM   4455  H  H    . ALA   A 1 289 ? 12.170  -10.195 38.933  1.00 35.34  ?  288 ALA   B H    1 
ATOM   4456  H  HA   . ALA   A 1 289 ? 9.771   -11.143 38.240  1.00 38.91  ?  288 ALA   B HA   1 
ATOM   4457  H  HB1  . ALA   A 1 289 ? 10.932  -13.010 37.399  1.00 37.29  ?  288 ALA   B HB1  1 
ATOM   4458  H  HB2  . ALA   A 1 289 ? 11.571  -11.682 36.808  1.00 37.29  ?  288 ALA   B HB2  1 
ATOM   4459  H  HB3  . ALA   A 1 289 ? 12.288  -12.445 38.002  1.00 37.29  ?  288 ALA   B HB3  1 
ATOM   4460  N  N    . LEU   A 1 290 ? 10.724  -11.735 41.036  1.00 35.73  ?  289 LEU   B N    1 
ATOM   4461  C  CA   . LEU   A 1 290 ? 10.666  -12.533 42.250  1.00 37.72  ?  289 LEU   B CA   1 
ATOM   4462  C  C    . LEU   A 1 290 ? 9.629   -11.943 43.193  1.00 40.86  ?  289 LEU   B C    1 
ATOM   4463  O  O    . LEU   A 1 290 ? 9.555   -10.718 43.350  1.00 42.02  ?  289 LEU   B O    1 
ATOM   4464  C  CB   . LEU   A 1 290 ? 12.051  -12.566 42.948  1.00 34.92  ?  289 LEU   B CB   1 
ATOM   4465  C  CG   . LEU   A 1 290 ? 13.293  -12.842 42.108  1.00 41.50  ?  289 LEU   B CG   1 
ATOM   4466  C  CD1  . LEU   A 1 290 ? 14.663  -12.487 42.753  1.00 34.41  ?  289 LEU   B CD1  1 
ATOM   4467  C  CD2  . LEU   A 1 290 ? 13.214  -14.359 41.712  1.00 43.18  ?  289 LEU   B CD2  1 
ATOM   4468  H  H    . LEU   A 1 290 ? 10.980  -10.925 41.166  1.00 42.88  ?  289 LEU   B H    1 
ATOM   4469  H  HA   . LEU   A 1 290 ? 10.404  -13.443 42.037  1.00 45.26  ?  289 LEU   B HA   1 
ATOM   4470  H  HB2  . LEU   A 1 290 ? 12.188  -11.700 43.364  1.00 41.91  ?  289 LEU   B HB2  1 
ATOM   4471  H  HB3  . LEU   A 1 290 ? 12.019  -13.259 43.626  1.00 41.91  ?  289 LEU   B HB3  1 
ATOM   4472  H  HG   . LEU   A 1 290 ? 13.285  -12.249 41.340  1.00 49.80  ?  289 LEU   B HG   1 
ATOM   4473  H  HD11 . LEU   A 1 290 ? 15.374  -12.736 42.142  1.00 41.30  ?  289 LEU   B HD11 1 
ATOM   4474  H  HD12 . LEU   A 1 290 ? 14.693  -11.532 42.925  1.00 41.30  ?  289 LEU   B HD12 1 
ATOM   4475  H  HD13 . LEU   A 1 290 ? 14.756  -12.975 43.586  1.00 41.30  ?  289 LEU   B HD13 1 
ATOM   4476  H  HD21 . LEU   A 1 290 ? 14.042  -14.615 41.275  1.00 51.82  ?  289 LEU   B HD21 1 
ATOM   4477  H  HD22 . LEU   A 1 290 ? 13.087  -14.889 42.515  1.00 51.82  ?  289 LEU   B HD22 1 
ATOM   4478  H  HD23 . LEU   A 1 290 ? 12.467  -14.490 41.108  1.00 51.82  ?  289 LEU   B HD23 1 
ATOM   4479  N  N    . LEU   A 1 291 ? 8.860   -12.813 43.852  1.00 44.16  ?  290 LEU   B N    1 
ATOM   4480  C  CA   . LEU   A 1 291 ? 7.729   -12.407 44.686  1.00 42.53  ?  290 LEU   B CA   1 
ATOM   4481  C  C    . LEU   A 1 291 ? 7.857   -13.027 46.068  1.00 38.34  ?  290 LEU   B C    1 
ATOM   4482  O  O    . LEU   A 1 291 ? 8.015   -14.245 46.176  1.00 41.80  ?  290 LEU   B O    1 
ATOM   4483  C  CB   . LEU   A 1 291 ? 6.397   -12.857 44.042  1.00 42.11  ?  290 LEU   B CB   1 
ATOM   4484  C  CG   . LEU   A 1 291 ? 5.095   -12.535 44.771  1.00 39.09  ?  290 LEU   B CG   1 
ATOM   4485  C  CD1  . LEU   A 1 291 ? 4.984   -11.010 44.942  1.00 39.37  ?  290 LEU   B CD1  1 
ATOM   4486  C  CD2  . LEU   A 1 291 ? 3.881   -13.098 44.047  1.00 38.57  ?  290 LEU   B CD2  1 
ATOM   4487  H  H    . LEU   A 1 291 ? 8.978   -13.664 43.831  1.00 52.99  ?  290 LEU   B H    1 
ATOM   4488  H  HA   . LEU   A 1 291 ? 7.734   -11.443 44.787  1.00 51.04  ?  290 LEU   B HA   1 
ATOM   4489  H  HB2  . LEU   A 1 291 ? 6.338   -12.438 43.169  1.00 50.53  ?  290 LEU   B HB2  1 
ATOM   4490  H  HB3  . LEU   A 1 291 ? 6.430   -13.822 43.945  1.00 50.53  ?  290 LEU   B HB3  1 
ATOM   4491  H  HG   . LEU   A 1 291 ? 5.104   -12.955 45.645  1.00 46.91  ?  290 LEU   B HG   1 
ATOM   4492  H  HD11 . LEU   A 1 291 ? 5.151   -10.783 45.871  1.00 47.24  ?  290 LEU   B HD11 1 
ATOM   4493  H  HD12 . LEU   A 1 291 ? 5.641   -10.579 44.373  1.00 47.24  ?  290 LEU   B HD12 1 
ATOM   4494  H  HD13 . LEU   A 1 291 ? 4.091   -10.728 44.688  1.00 47.24  ?  290 LEU   B HD13 1 
ATOM   4495  H  HD21 . LEU   A 1 291 ? 3.077   -12.812 44.508  1.00 46.28  ?  290 LEU   B HD21 1 
ATOM   4496  H  HD22 . LEU   A 1 291 ? 3.875   -12.766 43.136  1.00 46.28  ?  290 LEU   B HD22 1 
ATOM   4497  H  HD23 . LEU   A 1 291 ? 3.935   -14.066 44.046  1.00 46.28  ?  290 LEU   B HD23 1 
ATOM   4498  N  N    . THR   A 1 292 ? 7.761   -12.213 47.120  1.00 40.21  ?  291 THR   B N    1 
ATOM   4499  C  CA   . THR   A 1 292 ? 7.653   -12.748 48.473  1.00 44.69  ?  291 THR   B CA   1 
ATOM   4500  C  C    . THR   A 1 292 ? 6.510   -12.104 49.261  1.00 43.29  ?  291 THR   B C    1 
ATOM   4501  O  O    . THR   A 1 292 ? 6.140   -10.948 49.035  1.00 34.71  ?  291 THR   B O    1 
ATOM   4502  C  CB   . THR   A 1 292 ? 8.959   -12.561 49.236  1.00 49.94  ?  291 THR   B CB   1 
ATOM   4503  O  OG1  . THR   A 1 292 ? 9.150   -11.168 49.499  1.00 46.87  ?  291 THR   B OG1  1 
ATOM   4504  C  CG2  . THR   A 1 292 ? 10.139  -13.111 48.424  1.00 54.21  ?  291 THR   B CG2  1 
ATOM   4505  H  H    . THR   A 1 292 ? 7.755   -11.354 47.074  1.00 48.25  ?  291 THR   B H    1 
ATOM   4506  H  HA   . THR   A 1 292 ? 7.443   -13.693 48.405  1.00 53.63  ?  291 THR   B HA   1 
ATOM   4507  H  HB   . THR   A 1 292 ? 8.926   -13.044 50.076  1.00 59.93  ?  291 THR   B HB   1 
ATOM   4508  H  HG1  . THR   A 1 292 ? 9.845   -11.056 49.958  1.00 56.25  ?  291 THR   B HG1  1 
ATOM   4509  H  HG21 . THR   A 1 292 ? 10.962  -13.014 48.928  1.00 65.06  ?  291 THR   B HG21 1 
ATOM   4510  H  HG22 . THR   A 1 292 ? 9.998   -14.051 48.230  1.00 65.06  ?  291 THR   B HG22 1 
ATOM   4511  H  HG23 . THR   A 1 292 ? 10.222  -12.626 47.589  1.00 65.06  ?  291 THR   B HG23 1 
ATOM   4512  N  N    . LYS   A 1 293 ? 5.950   -12.858 50.206  1.00 50.17  ?  292 LYS   B N    1 
ATOM   4513  C  CA   . LYS   A 1 293 ? 4.862   -12.336 51.027  1.00 43.01  ?  292 LYS   B CA   1 
ATOM   4514  C  C    . LYS   A 1 293 ? 5.284   -12.136 52.474  1.00 44.76  ?  292 LYS   B C    1 
ATOM   4515  O  O    . LYS   A 1 293 ? 6.089   -12.895 53.030  1.00 51.82  ?  292 LYS   B O    1 
ATOM   4516  C  CB   . LYS   A 1 293 ? 3.646   -13.247 51.080  1.00 47.77  ?  292 LYS   B CB   1 
ATOM   4517  C  CG   . LYS   A 1 293 ? 3.302   -14.009 49.885  1.00 51.84  ?  292 LYS   B CG   1 
ATOM   4518  C  CD   . LYS   A 1 293 ? 1.776   -14.138 49.856  1.00 70.58  ?  292 LYS   B CD   1 
ATOM   4519  C  CE   . LYS   A 1 293 ? 1.244   -15.295 50.703  1.00 71.26  ?  292 LYS   B CE   1 
ATOM   4520  N  NZ   . LYS   A 1 293 ? -0.074  -15.757 50.170  1.00 60.04  ?  292 LYS   B NZ   1 
ATOM   4521  H  H    . LYS   A 1 293 ? 6.181   -13.666 50.388  1.00 60.20  ?  292 LYS   B H    1 
ATOM   4522  H  HA   . LYS   A 1 293 ? 4.624   -11.489 50.617  1.00 51.61  ?  292 LYS   B HA   1 
ATOM   4523  H  HB2  . LYS   A 1 293 ? 3.794   -13.893 51.788  1.00 57.33  ?  292 LYS   B HB2  1 
ATOM   4524  H  HB3  . LYS   A 1 293 ? 2.875   -12.697 51.289  1.00 57.33  ?  292 LYS   B HB3  1 
ATOM   4525  H  HG2  . LYS   A 1 293 ? 3.603   -13.543 49.089  1.00 62.21  ?  292 LYS   B HG2  1 
ATOM   4526  H  HG3  . LYS   A 1 293 ? 3.700   -14.893 49.922  1.00 62.21  ?  292 LYS   B HG3  1 
ATOM   4527  H  HD2  . LYS   A 1 293 ? 1.385   -13.318 50.196  1.00 84.70  ?  292 LYS   B HD2  1 
ATOM   4528  H  HD3  . LYS   A 1 293 ? 1.492   -14.286 48.940  1.00 84.70  ?  292 LYS   B HD3  1 
ATOM   4529  H  HE2  . LYS   A 1 293 ? 1.869   -16.036 50.673  1.00 85.52  ?  292 LYS   B HE2  1 
ATOM   4530  H  HE3  . LYS   A 1 293 ? 1.124   -15.000 51.619  1.00 85.52  ?  292 LYS   B HE3  1 
ATOM   4531  H  HZ1  . LYS   A 1 293 ? -0.364  -16.456 50.639  1.00 72.05  ?  292 LYS   B HZ1  1 
ATOM   4532  H  HZ2  . LYS   A 1 293 ? -0.673  -15.102 50.231  1.00 72.05  ?  292 LYS   B HZ2  1 
ATOM   4533  H  HZ3  . LYS   A 1 293 ? 0.009   -15.995 49.317  1.00 72.05  ?  292 LYS   B HZ3  1 
ATOM   4534  N  N    . SER   A 1 294 ? 4.683   -11.142 53.109  1.00 44.38  ?  293 SER   B N    1 
ATOM   4535  C  CA   . SER   A 1 294 ? 4.793   -11.017 54.550  1.00 48.30  ?  293 SER   B CA   1 
ATOM   4536  C  C    . SER   A 1 294 ? 3.546   -10.310 55.070  1.00 46.27  ?  293 SER   B C    1 
ATOM   4537  O  O    . SER   A 1 294 ? 2.821   -9.644  54.320  1.00 43.01  ?  293 SER   B O    1 
ATOM   4538  C  CB   . SER   A 1 294 ? 6.058   -10.256 54.936  1.00 44.37  ?  293 SER   B CB   1 
ATOM   4539  O  OG   . SER   A 1 294 ? 6.115   -9.077  54.150  1.00 51.67  ?  293 SER   B OG   1 
ATOM   4540  H  H    . SER   A 1 294 ? 4.210   -10.532 52.729  1.00 53.26  ?  293 SER   B H    1 
ATOM   4541  H  HA   . SER   A 1 294 ? 4.831   -11.894 54.962  1.00 57.96  ?  293 SER   B HA   1 
ATOM   4542  H  HB2  . SER   A 1 294 ? 6.024   -10.021 55.876  1.00 53.24  ?  293 SER   B HB2  1 
ATOM   4543  H  HB3  . SER   A 1 294 ? 6.837   -10.806 54.759  1.00 53.24  ?  293 SER   B HB3  1 
ATOM   4544  H  HG   . SER   A 1 294 ? 6.850   -8.687  54.270  1.00 62.01  ?  293 SER   B HG   1 
ATOM   4545  N  N    . SER   A 1 295 ? 3.298   -10.491 56.364  1.00 46.67  ?  294 SER   B N    1 
ATOM   4546  C  CA   . SER   A 1 295 ? 2.223   -9.794  57.044  1.00 54.72  ?  294 SER   B CA   1 
ATOM   4547  C  C    . SER   A 1 295 ? 2.671   -8.443  57.542  1.00 56.90  ?  294 SER   B C    1 
ATOM   4548  O  O    . SER   A 1 295 ? 1.827   -7.558  57.747  1.00 55.46  ?  294 SER   B O    1 
ATOM   4549  C  CB   . SER   A 1 295 ? 1.722   -10.617 58.234  1.00 51.14  ?  294 SER   B CB   1 
ATOM   4550  O  OG   . SER   A 1 295 ? 2.611   -10.484 59.340  1.00 57.88  ?  294 SER   B OG   1 
ATOM   4551  H  H    . SER   A 1 295 ? 3.746   -11.020 56.873  1.00 56.00  ?  294 SER   B H    1 
ATOM   4552  H  HA   . SER   A 1 295 ? 1.477   -9.679  56.434  1.00 65.66  ?  294 SER   B HA   1 
ATOM   4553  H  HB2  . SER   A 1 295 ? 0.844   -10.298 58.492  1.00 61.37  ?  294 SER   B HB2  1 
ATOM   4554  H  HB3  . SER   A 1 295 ? 1.674   -11.551 57.976  1.00 61.37  ?  294 SER   B HB3  1 
ATOM   4555  H  HG   . SER   A 1 295 ? 2.280   -10.850 60.020  1.00 69.46  ?  294 SER   B HG   1 
ATOM   4556  N  N    . GLU   A 1 296 ? 3.972   -8.277  57.739  1.00 50.68  ?  295 GLU   B N    1 
ATOM   4557  C  CA   . GLU   A 1 296 ? 4.526   -7.006  58.136  1.00 52.92  ?  295 GLU   B CA   1 
ATOM   4558  C  C    . GLU   A 1 296 ? 5.770   -6.753  57.309  1.00 56.17  ?  295 GLU   B C    1 
ATOM   4559  O  O    . GLU   A 1 296 ? 6.244   -7.620  56.563  1.00 46.63  ?  295 GLU   B O    1 
ATOM   4560  C  CB   . GLU   A 1 296 ? 4.867   -6.963  59.625  1.00 53.49  ?  295 GLU   B CB   1 
ATOM   4561  C  CG   . GLU   A 1 296 ? 3.657   -7.125  60.553  1.00 71.39  ?  295 GLU   B CG   1 
ATOM   4562  C  CD   . GLU   A 1 296 ? 3.995   -8.022  61.716  1.00 86.83  ?  295 GLU   B CD   1 
ATOM   4563  O  OE1  . GLU   A 1 296 ? 3.824   -7.593  62.879  1.00 96.54  ?  295 GLU   B OE1  1 
ATOM   4564  O  OE2  . GLU   A 1 296 ? 4.458   -9.155  61.458  1.00 83.89  -1 295 GLU   B OE2  1 
ATOM   4565  H  H    . GLU   A 1 296 ? 4.558   -8.899  57.647  1.00 60.82  ?  295 GLU   B H    1 
ATOM   4566  H  HA   . GLU   A 1 296 ? 3.875   -6.308  57.961  1.00 63.50  ?  295 GLU   B HA   1 
ATOM   4567  H  HB2  . GLU   A 1 296 ? 5.487   -7.682  59.822  1.00 64.19  ?  295 GLU   B HB2  1 
ATOM   4568  H  HB3  . GLU   A 1 296 ? 5.277   -6.106  59.825  1.00 64.19  ?  295 GLU   B HB3  1 
ATOM   4569  H  HG2  . GLU   A 1 296 ? 3.395   -6.258  60.898  1.00 85.67  ?  295 GLU   B HG2  1 
ATOM   4570  H  HG3  . GLU   A 1 296 ? 2.922   -7.522  60.060  1.00 85.67  ?  295 GLU   B HG3  1 
ATOM   4571  N  N    . TYR   A 1 297 ? 6.332   -5.563  57.510  1.00 53.79  ?  296 TYR   B N    1 
ATOM   4572  C  CA   . TYR   A 1 297 ? 7.454   -5.087  56.731  1.00 45.37  ?  296 TYR   B CA   1 
ATOM   4573  C  C    . TYR   A 1 297 ? 8.163   -4.011  57.533  1.00 48.52  ?  296 TYR   B C    1 
ATOM   4574  O  O    . TYR   A 1 297 ? 7.518   -3.073  58.003  1.00 46.05  ?  296 TYR   B O    1 
ATOM   4575  C  CB   . TYR   A 1 297 ? 6.997   -4.539  55.374  1.00 46.42  ?  296 TYR   B CB   1 
ATOM   4576  C  CG   . TYR   A 1 297 ? 8.182   -3.979  54.639  1.00 47.75  ?  296 TYR   B CG   1 
ATOM   4577  C  CD1  . TYR   A 1 297 ? 8.665   -2.723  54.966  1.00 43.41  ?  296 TYR   B CD1  1 
ATOM   4578  C  CD2  . TYR   A 1 297 ? 8.837   -4.706  53.640  1.00 43.80  ?  296 TYR   B CD2  1 
ATOM   4579  C  CE1  . TYR   A 1 297 ? 9.766   -2.188  54.318  1.00 42.75  ?  296 TYR   B CE1  1 
ATOM   4580  C  CE2  . TYR   A 1 297 ? 9.937   -4.189  53.006  1.00 40.18  ?  296 TYR   B CE2  1 
ATOM   4581  C  CZ   . TYR   A 1 297 ? 10.401  -2.932  53.357  1.00 39.71  ?  296 TYR   B CZ   1 
ATOM   4582  O  OH   . TYR   A 1 297 ? 11.490  -2.351  52.759  1.00 43.84  ?  296 TYR   B OH   1 
ATOM   4583  H  H    . TYR   A 1 297 ? 6.071   -5.004  58.108  1.00 64.55  ?  296 TYR   B H    1 
ATOM   4584  H  HA   . TYR   A 1 297 ? 8.074   -5.814  56.565  1.00 54.44  ?  296 TYR   B HA   1 
ATOM   4585  H  HB2  . TYR   A 1 297 ? 6.608   -5.253  54.845  1.00 55.71  ?  296 TYR   B HB2  1 
ATOM   4586  H  HB3  . TYR   A 1 297 ? 6.346   -3.832  55.506  1.00 55.71  ?  296 TYR   B HB3  1 
ATOM   4587  H  HD1  . TYR   A 1 297 ? 8.243   -2.230  55.632  1.00 52.09  ?  296 TYR   B HD1  1 
ATOM   4588  H  HD2  . TYR   A 1 297 ? 8.523   -5.549  53.403  1.00 52.56  ?  296 TYR   B HD2  1 
ATOM   4589  H  HE1  . TYR   A 1 297 ? 10.070  -1.336  54.532  1.00 51.30  ?  296 TYR   B HE1  1 
ATOM   4590  H  HE2  . TYR   A 1 297 ? 10.370  -4.679  52.345  1.00 48.22  ?  296 TYR   B HE2  1 
ATOM   4591  H  HH   . TYR   A 1 297 ? 11.752  -2.826  52.117  1.00 52.61  ?  296 TYR   B HH   1 
ATOM   4592  N  N    . LYS   A 1 298 ? 9.487   -4.136  57.666  1.00 49.08  ?  297 LYS   B N    1 
ATOM   4593  C  CA   . LYS   A 1 298 ? 10.355  -3.071  58.152  1.00 45.99  ?  297 LYS   B CA   1 
ATOM   4594  C  C    . LYS   A 1 298 ? 11.540  -3.020  57.196  1.00 48.95  ?  297 LYS   B C    1 
ATOM   4595  O  O    . LYS   A 1 298 ? 12.192  -4.042  56.957  1.00 50.43  ?  297 LYS   B O    1 
ATOM   4596  C  CB   . LYS   A 1 298 ? 10.824  -3.298  59.589  1.00 46.88  ?  297 LYS   B CB   1 
ATOM   4597  C  CG   . LYS   A 1 298 ? 9.741   -3.194  60.671  1.00 49.55  ?  297 LYS   B CG   1 
ATOM   4598  C  CD   . LYS   A 1 298 ? 10.326  -3.108  62.095  1.00 53.42  ?  297 LYS   B CD   1 
ATOM   4599  C  CE   . LYS   A 1 298 ? 11.313  -4.250  62.415  1.00 63.91  ?  297 LYS   B CE   1 
ATOM   4600  N  NZ   . LYS   A 1 298 ? 12.576  -3.802  63.128  1.00 81.60  ?  297 LYS   B NZ   1 
ATOM   4601  H  H    . LYS   A 1 298 ? 9.916   -4.856  57.474  1.00 58.89  ?  297 LYS   B H    1 
ATOM   4602  H  HA   . LYS   A 1 298 ? 9.886   -2.223  58.158  1.00 55.19  ?  297 LYS   B HA   1 
ATOM   4603  H  HB2  . LYS   A 1 298 ? 11.204  -4.188  59.648  1.00 56.26  ?  297 LYS   B HB2  1 
ATOM   4604  H  HB3  . LYS   A 1 298 ? 11.501  -2.634  59.796  1.00 56.26  ?  297 LYS   B HB3  1 
ATOM   4605  H  HG2  . LYS   A 1 298 ? 9.214   -2.394  60.515  1.00 59.46  ?  297 LYS   B HG2  1 
ATOM   4606  H  HG3  . LYS   A 1 298 ? 9.174   -3.979  60.627  1.00 59.46  ?  297 LYS   B HG3  1 
ATOM   4607  H  HD2  . LYS   A 1 298 ? 10.801  -2.268  62.190  1.00 64.11  ?  297 LYS   B HD2  1 
ATOM   4608  H  HD3  . LYS   A 1 298 ? 9.600   -3.153  62.736  1.00 64.11  ?  297 LYS   B HD3  1 
ATOM   4609  H  HE2  . LYS   A 1 298 ? 10.867  -4.895  62.985  1.00 76.70  ?  297 LYS   B HE2  1 
ATOM   4610  H  HE3  . LYS   A 1 298 ? 11.581  -4.671  61.583  1.00 76.70  ?  297 LYS   B HE3  1 
ATOM   4611  H  HZ1  . LYS   A 1 298 ? 13.105  -4.502  63.279  1.00 97.92  ?  297 LYS   B HZ1  1 
ATOM   4612  H  HZ2  . LYS   A 1 298 ? 13.014  -3.210  62.629  1.00 97.92  ?  297 LYS   B HZ2  1 
ATOM   4613  H  HZ3  . LYS   A 1 298 ? 12.367  -3.425  63.907  1.00 97.92  ?  297 LYS   B HZ3  1 
ATOM   4614  N  N    . GLY   A 1 299 ? 11.811  -1.851  56.627  1.00 42.06  ?  298 GLY   B N    1 
ATOM   4615  C  CA   . GLY   A 1 299 ? 12.832  -1.754  55.619  1.00 34.61  ?  298 GLY   B CA   1 
ATOM   4616  C  C    . GLY   A 1 299 ? 13.104  -0.326  55.219  1.00 39.08  ?  298 GLY   B C    1 
ATOM   4617  O  O    . GLY   A 1 299 ? 12.375  0.611   55.608  1.00 32.35  ?  298 GLY   B O    1 
ATOM   4618  H  H    . GLY   A 1 299 ? 11.415  -1.110  56.814  1.00 50.48  ?  298 GLY   B H    1 
ATOM   4619  H  HA2  . GLY   A 1 299 ? 13.656  -2.139  55.957  1.00 41.53  ?  298 GLY   B HA2  1 
ATOM   4620  H  HA3  . GLY   A 1 299 ? 12.553  -2.245  54.830  1.00 41.53  ?  298 GLY   B HA3  1 
ATOM   4621  N  N    . PRO   A 1 300 ? 14.187  -0.143  54.405  1.00 39.48  ?  299 PRO   B N    1 
ATOM   4622  C  CA   . PRO   A 1 300 ? 14.578  1.185   53.902  1.00 31.57  ?  299 PRO   B CA   1 
ATOM   4623  C  C    . PRO   A 1 300 ? 13.666  1.608   52.749  1.00 34.76  ?  299 PRO   B C    1 
ATOM   4624  O  O    . PRO   A 1 300 ? 13.827  1.156   51.624  1.00 33.32  ?  299 PRO   B O    1 
ATOM   4625  C  CB   . PRO   A 1 300 ? 16.026  0.958   53.432  1.00 31.91  ?  299 PRO   B CB   1 
ATOM   4626  C  CG   . PRO   A 1 300 ? 16.083  -0.479  53.060  1.00 32.14  ?  299 PRO   B CG   1 
ATOM   4627  C  CD   . PRO   A 1 300 ? 15.150  -1.203  54.032  1.00 29.95  ?  299 PRO   B CD   1 
ATOM   4628  H  HA   . PRO   A 1 300 ? 14.557  1.850   54.608  1.00 37.88  ?  299 PRO   B HA   1 
ATOM   4629  H  HB2  . PRO   A 1 300 ? 16.218  1.523   52.667  1.00 38.29  ?  299 PRO   B HB2  1 
ATOM   4630  H  HB3  . PRO   A 1 300 ? 16.643  1.155   54.153  1.00 38.29  ?  299 PRO   B HB3  1 
ATOM   4631  H  HG2  . PRO   A 1 300 ? 15.780  -0.592  52.146  1.00 38.56  ?  299 PRO   B HG2  1 
ATOM   4632  H  HG3  . PRO   A 1 300 ? 16.992  -0.804  53.152  1.00 38.56  ?  299 PRO   B HG3  1 
ATOM   4633  H  HD2  . PRO   A 1 300 ? 14.700  -1.943  53.595  1.00 35.94  ?  299 PRO   B HD2  1 
ATOM   4634  H  HD3  . PRO   A 1 300 ? 15.635  -1.521  54.809  1.00 35.94  ?  299 PRO   B HD3  1 
ATOM   4635  N  N    . ILE   A 1 301 ? 12.762  2.533   53.029  1.00 29.03  ?  300 ILE   B N    1 
ATOM   4636  C  CA   . ILE   A 1 301 ? 11.739  2.974   52.098  1.00 26.06  ?  300 ILE   B CA   1 
ATOM   4637  C  C    . ILE   A 1 301 ? 12.097  4.385   51.689  1.00 30.95  ?  300 ILE   B C    1 
ATOM   4638  O  O    . ILE   A 1 301 ? 12.588  5.179   52.520  1.00 26.61  ?  300 ILE   B O    1 
ATOM   4639  C  CB   . ILE   A 1 301 ? 10.352  2.953   52.770  1.00 34.71  ?  300 ILE   B CB   1 
ATOM   4640  C  CG1  . ILE   A 1 301 ? 9.997   1.535   53.188  1.00 34.11  ?  300 ILE   B CG1  1 
ATOM   4641  C  CG2  . ILE   A 1 301 ? 9.325   3.613   51.836  1.00 33.20  ?  300 ILE   B CG2  1 
ATOM   4642  C  CD1  . ILE   A 1 301 ? 9.963   0.559   52.040  1.00 33.14  ?  300 ILE   B CD1  1 
ATOM   4643  H  H    . ILE   A 1 301 ? 12.719  2.938   53.787  1.00 34.84  ?  300 ILE   B H    1 
ATOM   4644  H  HA   . ILE   A 1 301 ? 11.716  2.400   51.316  1.00 31.28  ?  300 ILE   B HA   1 
ATOM   4645  H  HB   . ILE   A 1 301 ? 10.358  3.475   53.588  1.00 41.65  ?  300 ILE   B HB   1 
ATOM   4646  H  HG12 . ILE   A 1 301 ? 10.658  1.221   53.825  1.00 40.93  ?  300 ILE   B HG12 1 
ATOM   4647  H  HG13 . ILE   A 1 301 ? 9.118   1.540   53.599  1.00 40.93  ?  300 ILE   B HG13 1 
ATOM   4648  H  HG21 . ILE   A 1 301 ? 8.432   3.372   52.129  1.00 39.84  ?  300 ILE   B HG21 1 
ATOM   4649  H  HG22 . ILE   A 1 301 ? 9.437   4.576   51.872  1.00 39.84  ?  300 ILE   B HG22 1 
ATOM   4650  H  HG23 . ILE   A 1 301 ? 9.472   3.297   50.931  1.00 39.84  ?  300 ILE   B HG23 1 
ATOM   4651  H  HD11 . ILE   A 1 301 ? 9.652   -0.300  52.365  1.00 39.76  ?  300 ILE   B HD11 1 
ATOM   4652  H  HD12 . ILE   A 1 301 ? 9.359   0.894   51.359  1.00 39.76  ?  300 ILE   B HD12 1 
ATOM   4653  H  HD13 . ILE   A 1 301 ? 10.857  0.471   51.675  1.00 39.76  ?  300 ILE   B HD13 1 
ATOM   4654  N  N    . THR   A 1 302 ? 11.815  4.723   50.430  1.00 26.81  ?  301 THR   B N    1 
ATOM   4655  C  CA   . THR   A 1 302 ? 12.125  6.058   49.973  1.00 30.05  ?  301 THR   B CA   1 
ATOM   4656  C  C    . THR   A 1 302 ? 10.985  6.711   49.215  1.00 30.00  ?  301 THR   B C    1 
ATOM   4657  O  O    . THR   A 1 302 ? 11.012  7.948   49.046  1.00 24.22  ?  301 THR   B O    1 
ATOM   4658  C  CB   . THR   A 1 302 ? 13.411  6.056   49.126  1.00 26.04  ?  301 THR   B CB   1 
ATOM   4659  O  OG1  . THR   A 1 302 ? 13.872  7.411   49.021  1.00 25.83  ?  301 THR   B OG1  1 
ATOM   4660  C  CG2  . THR   A 1 302 ? 13.151  5.519   47.756  1.00 30.64  ?  301 THR   B CG2  1 
ATOM   4661  H  H    . THR   A 1 302 ? 11.455  4.205   49.845  1.00 32.18  ?  301 THR   B H    1 
ATOM   4662  H  HA   . THR   A 1 302 ? 12.312  6.625   50.737  1.00 36.06  ?  301 THR   B HA   1 
ATOM   4663  H  HB   . THR   A 1 302 ? 14.084  5.493   49.541  1.00 31.25  ?  301 THR   B HB   1 
ATOM   4664  H  HG1  . THR   A 1 302 ? 14.036  7.719   49.785  1.00 30.99  ?  301 THR   B HG1  1 
ATOM   4665  H  HG21 . THR   A 1 302 ? 13.558  6.096   47.091  1.00 36.76  ?  301 THR   B HG21 1 
ATOM   4666  H  HG22 . THR   A 1 302 ? 13.526  4.628   47.672  1.00 36.76  ?  301 THR   B HG22 1 
ATOM   4667  H  HG23 . THR   A 1 302 ? 12.196  5.475   47.593  1.00 36.76  ?  301 THR   B HG23 1 
ATOM   4668  N  N    . ASP   A 1 303 ? 9.983   5.932   48.755  1.00 34.47  ?  302 ASP   B N    1 
ATOM   4669  C  CA   . ASP   A 1 303 ? 8.710   6.516   48.343  1.00 30.60  ?  302 ASP   B CA   1 
ATOM   4670  C  C    . ASP   A 1 303 ? 7.514   5.704   48.839  1.00 34.27  ?  302 ASP   B C    1 
ATOM   4671  O  O    . ASP   A 1 303 ? 7.579   4.485   48.951  1.00 34.97  ?  302 ASP   B O    1 
ATOM   4672  C  CB   . ASP   A 1 303 ? 8.531   6.606   46.794  1.00 34.61  ?  302 ASP   B CB   1 
ATOM   4673  C  CG   . ASP   A 1 303 ? 9.806   6.953   46.062  1.00 35.84  ?  302 ASP   B CG   1 
ATOM   4674  O  OD1  . ASP   A 1 303 ? 10.396  6.051   45.399  1.00 35.91  ?  302 ASP   B OD1  1 
ATOM   4675  O  OD2  . ASP   A 1 303 ? 10.162  8.155   46.098  1.00 33.09  -1 302 ASP   B OD2  1 
ATOM   4676  H  H    . ASP   A 1 303 ? 10.025  5.076   48.678  1.00 41.37  ?  302 ASP   B H    1 
ATOM   4677  H  HA   . ASP   A 1 303 ? 8.707   7.399   48.746  1.00 36.72  ?  302 ASP   B HA   1 
ATOM   4678  H  HB2  . ASP   A 1 303 ? 8.222   5.748   46.464  1.00 41.53  ?  302 ASP   B HB2  1 
ATOM   4679  H  HB3  . ASP   A 1 303 ? 7.877   7.293   46.594  1.00 41.53  ?  302 ASP   B HB3  1 
ATOM   4680  N  N    . VAL   A 1 304 ? 6.375   6.371   49.027  1.00 33.22  ?  303 VAL   B N    1 
ATOM   4681  C  CA   . VAL   A 1 304 ? 5.128   5.712   49.420  1.00 33.11  ?  303 VAL   B CA   1 
ATOM   4682  C  C    . VAL   A 1 304 ? 3.973   6.396   48.702  1.00 27.68  ?  303 VAL   B C    1 
ATOM   4683  O  O    . VAL   A 1 304 ? 3.812   7.618   48.783  1.00 27.87  ?  303 VAL   B O    1 
ATOM   4684  C  CB   . VAL   A 1 304 ? 4.890   5.754   50.947  1.00 30.19  ?  303 VAL   B CB   1 
ATOM   4685  C  CG1  . VAL   A 1 304 ? 3.707   4.892   51.340  1.00 31.74  ?  303 VAL   B CG1  1 
ATOM   4686  C  CG2  . VAL   A 1 304 ? 6.149   5.259   51.676  1.00 34.90  ?  303 VAL   B CG2  1 
ATOM   4687  H  H    . VAL   A 1 304 ? 6.298   7.222   48.932  1.00 39.87  ?  303 VAL   B H    1 
ATOM   4688  H  HA   . VAL   A 1 304 ? 5.169   4.784   49.142  1.00 39.74  ?  303 VAL   B HA   1 
ATOM   4689  H  HB   . VAL   A 1 304 ? 4.698   6.668   51.208  1.00 36.23  ?  303 VAL   B HB   1 
ATOM   4690  H  HG11 . VAL   A 1 304 ? 3.608   4.912   52.304  1.00 38.09  ?  303 VAL   B HG11 1 
ATOM   4691  H  HG12 . VAL   A 1 304 ? 2.907   5.244   50.918  1.00 38.09  ?  303 VAL   B HG12 1 
ATOM   4692  H  HG13 . VAL   A 1 304 ? 3.865   3.983   51.041  1.00 38.09  ?  303 VAL   B HG13 1 
ATOM   4693  H  HG21 . VAL   A 1 304 ? 6.024   5.369   52.632  1.00 41.88  ?  303 VAL   B HG21 1 
ATOM   4694  H  HG22 . VAL   A 1 304 ? 6.288   4.322   51.466  1.00 41.88  ?  303 VAL   B HG22 1 
ATOM   4695  H  HG23 . VAL   A 1 304 ? 6.911   5.781   51.380  1.00 41.88  ?  303 VAL   B HG23 1 
ATOM   4696  N  N    . PHE   A 1 305 ? 3.175   5.621   47.993  1.00 28.18  ?  304 PHE   B N    1 
ATOM   4697  C  CA   . PHE   A 1 305 ? 1.995   6.157   47.330  1.00 26.60  ?  304 PHE   B CA   1 
ATOM   4698  C  C    . PHE   A 1 305 ? 0.755   5.842   48.138  1.00 29.68  ?  304 PHE   B C    1 
ATOM   4699  O  O    . PHE   A 1 305 ? 0.555   4.691   48.547  1.00 29.46  ?  304 PHE   B O    1 
ATOM   4700  C  CB   . PHE   A 1 305 ? 1.867   5.582   45.929  1.00 36.78  ?  304 PHE   B CB   1 
ATOM   4701  C  CG   . PHE   A 1 305 ? 2.994   5.953   45.057  1.00 34.21  ?  304 PHE   B CG   1 
ATOM   4702  C  CD1  . PHE   A 1 305 ? 2.828   6.882   44.063  1.00 37.84  ?  304 PHE   B CD1  1 
ATOM   4703  C  CD2  . PHE   A 1 305 ? 4.254   5.409   45.257  1.00 35.40  ?  304 PHE   B CD2  1 
ATOM   4704  C  CE1  . PHE   A 1 305 ? 3.922   7.240   43.239  1.00 44.23  ?  304 PHE   B CE1  1 
ATOM   4705  C  CE2  . PHE   A 1 305 ? 5.325   5.765   44.440  1.00 39.39  ?  304 PHE   B CE2  1 
ATOM   4706  C  CZ   . PHE   A 1 305 ? 5.156   6.695   43.451  1.00 36.75  ?  304 PHE   B CZ   1 
ATOM   4707  H  H    . PHE   A 1 305 ? 3.294   4.777   47.879  1.00 33.81  ?  304 PHE   B H    1 
ATOM   4708  H  HA   . PHE   A 1 305 ? 2.072   7.121   47.266  1.00 31.92  ?  304 PHE   B HA   1 
ATOM   4709  H  HB2  . PHE   A 1 305 ? 1.838   4.614   45.986  1.00 44.13  ?  304 PHE   B HB2  1 
ATOM   4710  H  HB3  . PHE   A 1 305 ? 1.052   5.916   45.524  1.00 44.13  ?  304 PHE   B HB3  1 
ATOM   4711  H  HD1  . PHE   A 1 305 ? 1.997   7.277   43.930  1.00 45.41  ?  304 PHE   B HD1  1 
ATOM   4712  H  HD2  . PHE   A 1 305 ? 4.386   4.798   45.946  1.00 42.47  ?  304 PHE   B HD2  1 
ATOM   4713  H  HE1  . PHE   A 1 305 ? 3.800   7.851   42.548  1.00 53.07  ?  304 PHE   B HE1  1 
ATOM   4714  H  HE2  . PHE   A 1 305 ? 6.157   5.370   44.568  1.00 47.27  ?  304 PHE   B HE2  1 
ATOM   4715  H  HZ   . PHE   A 1 305 ? 5.878   6.954   42.926  1.00 44.10  ?  304 PHE   B HZ   1 
ATOM   4716  N  N    . TYR   A 1 306 ? -0.040  6.874   48.406  1.00 31.16  ?  305 TYR   B N    1 
ATOM   4717  C  CA   . TYR   A 1 306 ? -1.359  6.738   49.006  1.00 31.06  ?  305 TYR   B CA   1 
ATOM   4718  C  C    . TYR   A 1 306 ? -2.409  7.176   47.995  1.00 28.61  ?  305 TYR   B C    1 
ATOM   4719  O  O    . TYR   A 1 306 ? -2.220  8.148   47.268  1.00 30.35  ?  305 TYR   B O    1 
ATOM   4720  C  CB   . TYR   A 1 306 ? -1.537  7.589   50.272  1.00 25.22  ?  305 TYR   B CB   1 
ATOM   4721  C  CG   . TYR   A 1 306 ? -0.424  7.443   51.235  1.00 34.30  ?  305 TYR   B CG   1 
ATOM   4722  C  CD1  . TYR   A 1 306 ? -0.578  6.689   52.420  1.00 27.06  ?  305 TYR   B CD1  1 
ATOM   4723  C  CD2  . TYR   A 1 306 ? 0.803   8.046   50.989  1.00 34.50  ?  305 TYR   B CD2  1 
ATOM   4724  C  CE1  . TYR   A 1 306 ? 0.429   6.536   53.269  1.00 29.48  ?  305 TYR   B CE1  1 
ATOM   4725  C  CE2  . TYR   A 1 306 ? 1.828   7.898   51.874  1.00 30.72  ?  305 TYR   B CE2  1 
ATOM   4726  C  CZ   . TYR   A 1 306 ? 1.636   7.143   52.997  1.00 35.12  ?  305 TYR   B CZ   1 
ATOM   4727  O  OH   . TYR   A 1 306 ? 2.687   6.997   53.849  1.00 37.03  ?  305 TYR   B OH   1 
ATOM   4728  H  H    . TYR   A 1 306 ? 0.172   7.692   48.243  1.00 37.39  ?  305 TYR   B H    1 
ATOM   4729  H  HA   . TYR   A 1 306 ? -1.482  5.808   49.253  1.00 37.27  ?  305 TYR   B HA   1 
ATOM   4730  H  HB2  . TYR   A 1 306 ? -1.590  8.524   50.017  1.00 30.26  ?  305 TYR   B HB2  1 
ATOM   4731  H  HB3  . TYR   A 1 306 ? -2.355  7.320   50.719  1.00 30.26  ?  305 TYR   B HB3  1 
ATOM   4732  H  HD1  . TYR   A 1 306 ? -1.399  6.294   52.608  1.00 32.47  ?  305 TYR   B HD1  1 
ATOM   4733  H  HD2  . TYR   A 1 306 ? 0.925   8.553   50.219  1.00 41.41  ?  305 TYR   B HD2  1 
ATOM   4734  H  HE1  . TYR   A 1 306 ? 0.322   6.026   54.039  1.00 35.37  ?  305 TYR   B HE1  1 
ATOM   4735  H  HE2  . TYR   A 1 306 ? 2.649   8.305   51.715  1.00 36.87  ?  305 TYR   B HE2  1 
ATOM   4736  H  HH   . TYR   A 1 306 ? 3.326   7.483   53.602  1.00 44.44  ?  305 TYR   B HH   1 
ATOM   4737  N  N    . LYS   A 1 307 ? -3.509  6.448   47.935  1.00 34.21  ?  306 LYS   B N    1 
ATOM   4738  C  CA   . LYS   A 1 307 ? -4.638  6.851   47.117  1.00 27.31  ?  306 LYS   B CA   1 
ATOM   4739  C  C    . LYS   A 1 307 ? -5.425  7.921   47.871  1.00 23.90  ?  306 LYS   B C    1 
ATOM   4740  O  O    . LYS   A 1 307 ? -5.401  7.989   49.094  1.00 29.81  ?  306 LYS   B O    1 
ATOM   4741  C  CB   . LYS   A 1 307 ? -5.497  5.633   46.810  1.00 34.00  ?  306 LYS   B CB   1 
ATOM   4742  C  CG   . LYS   A 1 307 ? -5.089  4.847   45.559  1.00 41.18  ?  306 LYS   B CG   1 
ATOM   4743  C  CD   . LYS   A 1 307 ? -6.094  3.732   45.282  1.00 39.56  ?  306 LYS   B CD   1 
ATOM   4744  C  CE   . LYS   A 1 307 ? -5.443  2.542   44.590  1.00 46.32  ?  306 LYS   B CE   1 
ATOM   4745  N  NZ   . LYS   A 1 307 ? -5.810  2.456   43.127  1.00 47.66  ?  306 LYS   B NZ   1 
ATOM   4746  H  H    . LYS   A 1 307 ? -3.628  5.710   48.361  1.00 41.05  ?  306 LYS   B H    1 
ATOM   4747  H  HA   . LYS   A 1 307 ? -4.361  7.224   46.266  1.00 32.77  ?  306 LYS   B HA   1 
ATOM   4748  H  HB2  . LYS   A 1 307 ? -5.447  5.024   47.564  1.00 40.81  ?  306 LYS   B HB2  1 
ATOM   4749  H  HB3  . LYS   A 1 307 ? -6.412  5.927   46.682  1.00 40.81  ?  306 LYS   B HB3  1 
ATOM   4750  H  HG2  . LYS   A 1 307 ? -5.067  5.442   44.793  1.00 49.41  ?  306 LYS   B HG2  1 
ATOM   4751  H  HG3  . LYS   A 1 307 ? -4.214  4.449   45.695  1.00 49.41  ?  306 LYS   B HG3  1 
ATOM   4752  H  HD2  . LYS   A 1 307 ? -6.472  3.426   46.122  1.00 47.47  ?  306 LYS   B HD2  1 
ATOM   4753  H  HD3  . LYS   A 1 307 ? -6.797  4.071   44.706  1.00 47.47  ?  306 LYS   B HD3  1 
ATOM   4754  H  HE2  . LYS   A 1 307 ? -4.479  2.625   44.655  1.00 55.59  ?  306 LYS   B HE2  1 
ATOM   4755  H  HE3  . LYS   A 1 307 ? -5.735  1.724   45.023  1.00 55.59  ?  306 LYS   B HE3  1 
ATOM   4756  H  HZ1  . LYS   A 1 307 ? -5.285  1.867   42.715  1.00 57.20  ?  306 LYS   B HZ1  1 
ATOM   4757  H  HZ2  . LYS   A 1 307 ? -6.657  2.198   43.041  1.00 57.20  ?  306 LYS   B HZ2  1 
ATOM   4758  H  HZ3  . LYS   A 1 307 ? -5.710  3.252   42.741  1.00 57.20  ?  306 LYS   B HZ3  1 
ATOM   4759  N  N    . GLU   A 1 308 ? -6.150  8.743   47.136  1.00 34.28  ?  307 GLU   B N    1 
ATOM   4760  C  CA   . GLU   A 1 308 ? -6.821  9.906   47.703  1.00 33.75  ?  307 GLU   B CA   1 
ATOM   4761  C  C    . GLU   A 1 308 ? -7.981  10.251  46.770  1.00 37.16  ?  307 GLU   B C    1 
ATOM   4762  O  O    . GLU   A 1 308 ? -8.062  9.743   45.638  1.00 30.96  ?  307 GLU   B O    1 
ATOM   4763  C  CB   . GLU   A 1 308 ? -5.813  11.059  47.883  1.00 36.63  ?  307 GLU   B CB   1 
ATOM   4764  C  CG   . GLU   A 1 308 ? -6.313  12.312  48.605  1.00 33.90  ?  307 GLU   B CG   1 
ATOM   4765  C  CD   . GLU   A 1 308 ? -6.989  12.026  49.930  1.00 43.93  ?  307 GLU   B CD   1 
ATOM   4766  O  OE1  . GLU   A 1 308 ? -6.272  12.082  50.959  1.00 38.86  ?  307 GLU   B OE1  1 
ATOM   4767  O  OE2  . GLU   A 1 308 ? -8.274  11.793  49.952  1.00 38.13  -1 307 GLU   B OE2  1 
ATOM   4768  H  H    . GLU   A 1 308 ? -6.273  8.651   46.290  1.00 41.13  ?  307 GLU   B H    1 
ATOM   4769  H  HA   . GLU   A 1 308 ? -7.199  9.722   48.577  1.00 40.50  ?  307 GLU   B HA   1 
ATOM   4770  H  HB2  . GLU   A 1 308 ? -5.059  10.721  48.392  1.00 43.96  ?  307 GLU   B HB2  1 
ATOM   4771  H  HB3  . GLU   A 1 308 ? -5.519  11.339  47.002  1.00 43.96  ?  307 GLU   B HB3  1 
ATOM   4772  H  HG2  . GLU   A 1 308 ? -5.557  12.894  48.780  1.00 40.68  ?  307 GLU   B HG2  1 
ATOM   4773  H  HG3  . GLU   A 1 308 ? -6.956  12.765  48.037  1.00 40.68  ?  307 GLU   B HG3  1 
ATOM   4774  N  N    . ASN   A 1 309 ? -8.911  11.088  47.274  1.00 29.43  ?  308 ASN   B N    1 
ATOM   4775  C  CA   . ASN   A 1 309 ? -9.854  11.754  46.397  1.00 29.75  ?  308 ASN   B CA   1 
ATOM   4776  C  C    . ASN   A 1 309 ? -9.961  13.200  46.855  1.00 34.36  ?  308 ASN   B C    1 
ATOM   4777  O  O    . ASN   A 1 309 ? -9.570  14.119  46.117  1.00 33.71  ?  308 ASN   B O    1 
ATOM   4778  C  CB   . ASN   A 1 309 ? -11.211 11.052  46.405  1.00 35.71  ?  308 ASN   B CB   1 
ATOM   4779  C  CG   . ASN   A 1 309 ? -12.212 11.668  45.384  1.00 31.41  ?  308 ASN   B CG   1 
ATOM   4780  O  OD1  . ASN   A 1 309 ? -12.812 12.680  45.650  1.00 37.22  ?  308 ASN   B OD1  1 
ATOM   4781  N  ND2  . ASN   A 1 309 ? -12.330 11.084  44.231  1.00 24.49  ?  308 ASN   B ND2  1 
ATOM   4782  H  H    . ASN   A 1 309 ? -9.002  11.275  48.109  1.00 35.31  ?  308 ASN   B H    1 
ATOM   4783  H  HA   . ASN   A 1 309 ? -9.556  11.724  45.474  1.00 35.71  ?  308 ASN   B HA   1 
ATOM   4784  H  HB2  . ASN   A 1 309 ? -11.086 10.118  46.176  1.00 42.85  ?  308 ASN   B HB2  1 
ATOM   4785  H  HB3  . ASN   A 1 309 ? -11.601 11.128  47.290  1.00 42.85  ?  308 ASN   B HB3  1 
ATOM   4786  H  HD21 . ASN   A 1 309 ? -11.865 10.383  44.055  1.00 29.39  ?  308 ASN   B HD21 1 
ATOM   4787  H  HD22 . ASN   A 1 309 ? -12.874 11.398  43.644  1.00 29.39  ?  308 ASN   B HD22 1 
ATOM   4788  N  N    . SER   A 1 310 ? -10.494 13.417  48.063  1.00 32.49  ?  309 SER   B N    1 
ATOM   4789  C  CA   . SER   A 1 310 ? -10.610 14.772  48.587  1.00 32.88  ?  309 SER   B CA   1 
ATOM   4790  C  C    . SER   A 1 310 ? -10.398 14.732  50.083  1.00 37.38  ?  309 SER   B C    1 
ATOM   4791  O  O    . SER   A 1 310 ? -11.100 13.998  50.788  1.00 35.39  ?  309 SER   B O    1 
ATOM   4792  C  CB   . SER   A 1 310 ? -11.976 15.383  48.265  1.00 37.44  ?  309 SER   B CB   1 
ATOM   4793  O  OG   . SER   A 1 310 ? -12.036 16.733  48.685  1.00 47.44  ?  309 SER   B OG   1 
ATOM   4794  H  H    . SER   A 1 310 ? -10.790 12.803  48.587  1.00 38.99  ?  309 SER   B H    1 
ATOM   4795  H  HA   . SER   A 1 310 ? -9.926  15.331  48.187  1.00 39.46  ?  309 SER   B HA   1 
ATOM   4796  H  HB2  . SER   A 1 310 ? -12.122 15.343  47.307  1.00 44.92  ?  309 SER   B HB2  1 
ATOM   4797  H  HB3  . SER   A 1 310 ? -12.664 14.878  48.727  1.00 44.92  ?  309 SER   B HB3  1 
ATOM   4798  H  HG   . SER   A 1 310 ? -12.717 17.104  48.361  1.00 56.93  ?  309 SER   B HG   1 
ATOM   4799  N  N    . TYR   A 1 311 ? -9.436  15.520  50.552  1.00 36.85  ?  310 TYR   B N    1 
ATOM   4800  C  CA   . TYR   A 1 311 ? -9.111  15.613  51.961  1.00 32.95  ?  310 TYR   B CA   1 
ATOM   4801  C  C    . TYR   A 1 311 ? -9.259  17.051  52.405  1.00 34.98  ?  310 TYR   B C    1 
ATOM   4802  O  O    . TYR   A 1 311 ? -8.840  17.976  51.707  1.00 37.04  ?  310 TYR   B O    1 
ATOM   4803  C  CB   . TYR   A 1 311 ? -7.679  15.147  52.248  1.00 41.74  ?  310 TYR   B CB   1 
ATOM   4804  C  CG   . TYR   A 1 311 ? -7.248  15.471  53.674  1.00 44.36  ?  310 TYR   B CG   1 
ATOM   4805  C  CD1  . TYR   A 1 311 ? -7.683  14.708  54.751  1.00 39.80  ?  310 TYR   B CD1  1 
ATOM   4806  C  CD2  . TYR   A 1 311 ? -6.439  16.549  53.933  1.00 37.83  ?  310 TYR   B CD2  1 
ATOM   4807  C  CE1  . TYR   A 1 311 ? -7.297  15.005  56.036  1.00 38.08  ?  310 TYR   B CE1  1 
ATOM   4808  C  CE2  . TYR   A 1 311 ? -6.061  16.865  55.203  1.00 39.42  ?  310 TYR   B CE2  1 
ATOM   4809  C  CZ   . TYR   A 1 311 ? -6.491  16.104  56.258  1.00 41.53  ?  310 TYR   B CZ   1 
ATOM   4810  O  OH   . TYR   A 1 311 ? -6.088  16.453  57.521  1.00 38.43  ?  310 TYR   B OH   1 
ATOM   4811  H  H    . TYR   A 1 311 ? -8.947  16.023  50.055  1.00 44.22  ?  310 TYR   B H    1 
ATOM   4812  H  HA   . TYR   A 1 311 ? -9.719  15.051  52.466  1.00 39.54  ?  310 TYR   B HA   1 
ATOM   4813  H  HB2  . TYR   A 1 311 ? -7.627  14.186  52.126  1.00 50.08  ?  310 TYR   B HB2  1 
ATOM   4814  H  HB3  . TYR   A 1 311 ? -7.071  15.593  51.638  1.00 50.08  ?  310 TYR   B HB3  1 
ATOM   4815  H  HD1  . TYR   A 1 311 ? -8.245  13.983  54.600  1.00 47.77  ?  310 TYR   B HD1  1 
ATOM   4816  H  HD2  . TYR   A 1 311 ? -6.142  17.075  53.226  1.00 45.39  ?  310 TYR   B HD2  1 
ATOM   4817  H  HE1  . TYR   A 1 311 ? -7.576  14.474  56.746  1.00 45.70  ?  310 TYR   B HE1  1 
ATOM   4818  H  HE2  . TYR   A 1 311 ? -5.510  17.599  55.354  1.00 47.30  ?  310 TYR   B HE2  1 
ATOM   4819  H  HH   . TYR   A 1 311 ? -5.697  17.196  57.503  1.00 46.12  ?  310 TYR   B HH   1 
ATOM   4820  N  N    . THR   A 1 312 ? -9.866  17.234  53.571  1.00 46.15  ?  311 THR   B N    1 
ATOM   4821  C  CA   . THR   A 1 312 ? -10.005 18.556  54.173  1.00 48.91  ?  311 THR   B CA   1 
ATOM   4822  C  C    . THR   A 1 312 ? -9.646  18.451  55.647  1.00 42.37  ?  311 THR   B C    1 
ATOM   4823  O  O    . THR   A 1 312 ? -10.108 17.544  56.349  1.00 40.10  ?  311 THR   B O    1 
ATOM   4824  C  CB   . THR   A 1 312 ? -11.410 19.141  53.955  1.00 38.96  ?  311 THR   B CB   1 
ATOM   4825  O  OG1  . THR   A 1 312 ? -11.695 19.166  52.541  1.00 36.84  ?  311 THR   B OG1  1 
ATOM   4826  C  CG2  . THR   A 1 312 ? -11.401 20.551  54.487  1.00 37.83  ?  311 THR   B CG2  1 
ATOM   4827  H  H    . THR   A 1 312 ? -10.210 16.601  54.040  1.00 55.39  ?  311 THR   B H    1 
ATOM   4828  H  HA   . THR   A 1 312 ? -9.385  19.180  53.763  1.00 58.70  ?  311 THR   B HA   1 
ATOM   4829  H  HB   . THR   A 1 312 ? -12.092 18.616  54.403  1.00 46.75  ?  311 THR   B HB   1 
ATOM   4830  H  HG1  . THR   A 1 312 ? -11.097 19.594  52.135  1.00 44.20  ?  311 THR   B HG1  1 
ATOM   4831  H  HG21 . THR   A 1 312 ? -12.052 21.090  54.011  1.00 45.40  ?  311 THR   B HG21 1 
ATOM   4832  H  HG22 . THR   A 1 312 ? -11.623 20.550  55.432  1.00 45.40  ?  311 THR   B HG22 1 
ATOM   4833  H  HG23 . THR   A 1 312 ? -10.522 20.943  54.371  1.00 45.40  ?  311 THR   B HG23 1 
ATOM   4834  N  N    . THR   A 1 313 ? -8.757  19.336  56.083  1.00 46.02  ?  312 THR   B N    1 
ATOM   4835  C  CA   . THR   A 1 313 ? -8.235  19.280  57.434  1.00 43.79  ?  312 THR   B CA   1 
ATOM   4836  C  C    . THR   A 1 313 ? -9.331  19.624  58.449  1.00 49.04  ?  312 THR   B C    1 
ATOM   4837  O  O    . THR   A 1 313 ? -10.361 20.216  58.123  1.00 44.06  ?  312 THR   B O    1 
ATOM   4838  C  CB   . THR   A 1 313 ? -7.048  20.234  57.558  1.00 43.51  ?  312 THR   B CB   1 
ATOM   4839  O  OG1  . THR   A 1 313 ? -6.383  20.028  58.803  1.00 42.73  ?  312 THR   B OG1  1 
ATOM   4840  C  CG2  . THR   A 1 313 ? -7.506  21.667  57.479  1.00 46.31  ?  312 THR   B CG2  1 
ATOM   4841  H  H    . THR   A 1 313 ? -8.439  19.981  55.610  1.00 55.23  ?  312 THR   B H    1 
ATOM   4842  H  HA   . THR   A 1 313 ? -7.926  18.385  57.643  1.00 52.55  ?  312 THR   B HA   1 
ATOM   4843  H  HB   . THR   A 1 313 ? -6.431  20.064  56.829  1.00 52.21  ?  312 THR   B HB   1 
ATOM   4844  H  HG1  . THR   A 1 313 ? -5.832  20.648  58.940  1.00 51.27  ?  312 THR   B HG1  1 
ATOM   4845  H  HG21 . THR   A 1 313 ? -6.748  22.249  57.309  1.00 55.58  ?  312 THR   B HG21 1 
ATOM   4846  H  HG22 . THR   A 1 313 ? -8.149  21.771  56.760  1.00 55.58  ?  312 THR   B HG22 1 
ATOM   4847  H  HG23 . THR   A 1 313 ? -7.923  21.929  58.314  1.00 55.58  ?  312 THR   B HG23 1 
ATOM   4848  N  N    . THR   A 1 314 ? -9.106  19.211  59.695  1.00 52.48  ?  313 THR   B N    1 
ATOM   4849  C  CA   . THR   A 1 314 ? -9.919  19.664  60.811  1.00 51.71  ?  313 THR   B CA   1 
ATOM   4850  C  C    . THR   A 1 314 ? -9.207  20.669  61.698  1.00 56.82  ?  313 THR   B C    1 
ATOM   4851  O  O    . THR   A 1 314 ? -9.887  21.403  62.421  1.00 56.95  ?  313 THR   B O    1 
ATOM   4852  C  CB   . THR   A 1 314 ? -10.366 18.471  61.667  1.00 43.20  ?  313 THR   B CB   1 
ATOM   4853  O  OG1  . THR   A 1 314 ? -9.239  17.637  61.997  1.00 63.69  ?  313 THR   B OG1  1 
ATOM   4854  C  CG2  . THR   A 1 314 ? -11.342 17.643  60.894  1.00 50.94  ?  313 THR   B CG2  1 
ATOM   4855  H  H    . THR   A 1 314 ? -8.482  18.662  59.917  1.00 62.98  ?  313 THR   B H    1 
ATOM   4856  H  HA   . THR   A 1 314 ? -10.721 20.086  60.465  1.00 62.05  ?  313 THR   B HA   1 
ATOM   4857  H  HB   . THR   A 1 314 ? -10.774 18.800  62.483  1.00 51.84  ?  313 THR   B HB   1 
ATOM   4858  H  HG1  . THR   A 1 314 ? -9.506  16.896  62.288  1.00 76.43  ?  313 THR   B HG1  1 
ATOM   4859  H  HG21 . THR   A 1 314 ? -11.566 16.842  61.393  1.00 61.13  ?  313 THR   B HG21 1 
ATOM   4860  H  HG22 . THR   A 1 314 ? -12.153 18.150  60.732  1.00 61.13  ?  313 THR   B HG22 1 
ATOM   4861  H  HG23 . THR   A 1 314 ? -10.956 17.385  60.042  1.00 61.13  ?  313 THR   B HG23 1 
ATOM   4862  N  N    . ILE   A 1 315 ? -7.881  20.750  61.617  1.00 49.42  ?  314 ILE   B N    1 
ATOM   4863  C  CA   . ILE   A 1 315 ? -7.070  21.639  62.430  1.00 54.47  ?  314 ILE   B CA   1 
ATOM   4864  C  C    . ILE   A 1 315 ? -7.664  23.039  62.463  1.00 55.17  ?  314 ILE   B C    1 
ATOM   4865  O  O    . ILE   A 1 315 ? -8.123  23.537  61.439  1.00 60.70  ?  314 ILE   B O    1 
ATOM   4866  C  CB   . ILE   A 1 315 ? -5.610  21.658  61.917  1.00 51.75  ?  314 ILE   B CB   1 
ATOM   4867  C  CG1  . ILE   A 1 315 ? -4.835  20.464  62.489  1.00 45.47  ?  314 ILE   B CG1  1 
ATOM   4868  C  CG2  . ILE   A 1 315 ? -4.913  22.977  62.287  1.00 48.92  ?  314 ILE   B CG2  1 
ATOM   4869  C  CD1  . ILE   A 1 315 ? -3.824  19.846  61.518  1.00 47.90  ?  314 ILE   B CD1  1 
ATOM   4870  N  N    . GLU   B 1 2   ? 50.151  6.109   98.026  1.00 53.92  ?  1   GLU   A N    1 
ATOM   4871  C  CA   . GLU   B 1 2   ? 50.992  5.569   96.976  1.00 41.79  ?  1   GLU   A CA   1 
ATOM   4872  C  C    . GLU   B 1 2   ? 50.564  4.278   96.290  1.00 38.88  ?  1   GLU   A C    1 
ATOM   4873  O  O    . GLU   B 1 2   ? 51.305  3.764   95.459  1.00 52.34  ?  1   GLU   A O    1 
ATOM   4874  C  CB   . GLU   B 1 2   ? 52.399  5.346   97.556  1.00 40.79  ?  1   GLU   A CB   1 
ATOM   4875  C  CG   . GLU   B 1 2   ? 52.745  3.901   98.044  1.00 35.17  ?  1   GLU   A CG   1 
ATOM   4876  C  CD   . GLU   B 1 2   ? 54.269  3.843   98.225  1.00 56.55  ?  1   GLU   A CD   1 
ATOM   4877  O  OE1  . GLU   B 1 2   ? 54.849  4.946   98.129  1.00 49.16  ?  1   GLU   A OE1  1 
ATOM   4878  O  OE2  . GLU   B 1 2   ? 54.900  2.769   98.444  1.00 60.96  ?  1   GLU   A OE2  1 
ATOM   4879  H  H    . GLU   B 1 2   ? 49.588  5.550   98.344  1.00 64.70  ?  1   GLU   A H    1 
ATOM   4880  H  HA   . GLU   B 1 2   ? 50.950  6.228   96.266  1.00 50.15  ?  1   GLU   A HA   1 
ATOM   4881  H  HB2  . GLU   B 1 2   ? 53.045  5.574   96.870  1.00 48.94  ?  1   GLU   A HB2  1 
ATOM   4882  H  HB3  . GLU   B 1 2   ? 52.504  5.934   98.320  1.00 48.94  ?  1   GLU   A HB3  1 
ATOM   4883  H  HG2  . GLU   B 1 2   ? 52.310  3.717   98.891  1.00 42.20  ?  1   GLU   A HG2  1 
ATOM   4884  H  HG3  . GLU   B 1 2   ? 52.472  3.247   97.382  1.00 42.20  ?  1   GLU   A HG3  1 
ATOM   4885  N  N    . VAL   B 1 3   ? 49.389  3.755   96.620  1.00 48.27  ?  2   VAL   A N    1 
ATOM   4886  C  CA   . VAL   B 1 3   ? 48.726  2.756   95.783  1.00 45.01  ?  2   VAL   A CA   1 
ATOM   4887  C  C    . VAL   B 1 3   ? 47.388  3.338   95.336  1.00 46.08  ?  2   VAL   A C    1 
ATOM   4888  O  O    . VAL   B 1 3   ? 46.338  2.999   95.893  1.00 46.58  ?  2   VAL   A O    1 
ATOM   4889  C  CB   . VAL   B 1 3   ? 48.538  1.434   96.538  1.00 41.37  ?  2   VAL   A CB   1 
ATOM   4890  C  CG1  . VAL   B 1 3   ? 47.794  0.470   95.709  1.00 45.45  ?  2   VAL   A CG1  1 
ATOM   4891  C  CG2  . VAL   B 1 3   ? 49.873  0.838   96.935  1.00 46.52  ?  2   VAL   A CG2  1 
ATOM   4892  H  H    . VAL   B 1 3   ? 48.950  3.963   97.329  1.00 57.92  ?  2   VAL   A H    1 
ATOM   4893  H  HA   . VAL   B 1 3   ? 49.266  2.567   95.000  1.00 54.01  ?  2   VAL   A HA   1 
ATOM   4894  H  HB   . VAL   B 1 3   ? 48.031  1.616   97.345  1.00 49.64  ?  2   VAL   A HB   1 
ATOM   4895  H  HG11 . VAL   B 1 3   ? 48.023  -0.430  95.988  1.00 54.54  ?  2   VAL   A HG11 1 
ATOM   4896  H  HG12 . VAL   B 1 3   ? 46.843  0.620   95.826  1.00 54.54  ?  2   VAL   A HG12 1 
ATOM   4897  H  HG13 . VAL   B 1 3   ? 48.037  0.599   94.779  1.00 54.54  ?  2   VAL   A HG13 1 
ATOM   4898  H  HG21 . VAL   B 1 3   ? 49.720  0.006   97.408  1.00 55.83  ?  2   VAL   A HG21 1 
ATOM   4899  H  HG22 . VAL   B 1 3   ? 50.396  0.673   96.135  1.00 55.83  ?  2   VAL   A HG22 1 
ATOM   4900  H  HG23 . VAL   B 1 3   ? 50.340  1.465   97.511  1.00 55.83  ?  2   VAL   A HG23 1 
ATOM   4901  N  N    . ARG   B 1 4   ? 47.417  4.236   94.348  1.00 49.31  ?  3   ARG   A N    1 
ATOM   4902  C  CA   . ARG   B 1 4   ? 46.202  4.715   93.691  1.00 63.30  ?  3   ARG   A CA   1 
ATOM   4903  C  C    . ARG   B 1 4   ? 45.696  3.701   92.658  1.00 56.49  ?  3   ARG   A C    1 
ATOM   4904  O  O    . ARG   B 1 4   ? 46.470  2.907   92.098  1.00 49.48  ?  3   ARG   A O    1 
ATOM   4905  C  CB   . ARG   B 1 4   ? 46.458  6.075   93.016  1.00 67.66  ?  3   ARG   A CB   1 
ATOM   4906  C  CG   . ARG   B 1 4   ? 46.816  7.212   93.972  1.00 87.93  ?  3   ARG   A CG   1 
ATOM   4907  C  CD   . ARG   B 1 4   ? 47.856  8.207   93.415  1.00 128.76 ?  3   ARG   A CD   1 
ATOM   4908  N  NE   . ARG   B 1 4   ? 48.795  8.607   94.461  1.00 96.51  ?  3   ARG   A NE   1 
ATOM   4909  C  CZ   . ARG   B 1 4   ? 48.948  9.843   94.918  1.00 98.31  ?  3   ARG   A CZ   1 
ATOM   4910  N  NH1  . ARG   B 1 4   ? 48.321  10.869  94.366  1.00 109.75 ?  3   ARG   A NH1  1 
ATOM   4911  N  NH2  . ARG   B 1 4   ? 49.747  10.050  95.960  1.00 69.99  ?  3   ARG   A NH2  1 
ATOM   4912  H  H    . ARG   B 1 4   ? 48.138  4.587   94.037  1.00 59.17  ?  3   ARG   A H    1 
ATOM   4913  H  HA   . ARG   B 1 4   ? 45.504  4.832   94.354  1.00 75.96  ?  3   ARG   A HA   1 
ATOM   4914  H  HB2  . ARG   B 1 4   ? 47.195  5.975   92.394  1.00 81.19  ?  3   ARG   A HB2  1 
ATOM   4915  H  HB3  . ARG   B 1 4   ? 45.655  6.337   92.540  1.00 81.19  ?  3   ARG   A HB3  1 
ATOM   4916  H  HG2  . ARG   B 1 4   ? 46.011  7.713   94.175  1.00 105.52 ?  3   ARG   A HG2  1 
ATOM   4917  H  HG3  . ARG   B 1 4   ? 47.183  6.831   94.785  1.00 105.52 ?  3   ARG   A HG3  1 
ATOM   4918  H  HD2  . ARG   B 1 4   ? 48.355  7.787   92.696  1.00 154.51 ?  3   ARG   A HD2  1 
ATOM   4919  H  HD3  . ARG   B 1 4   ? 47.404  9.000   93.086  1.00 154.51 ?  3   ARG   A HD3  1 
ATOM   4920  H  HE   . ARG   B 1 4   ? 49.287  7.993   94.808  1.00 115.81 ?  3   ARG   A HE   1 
ATOM   4921  H  HH11 . ARG   B 1 4   ? 47.799  10.742  93.694  1.00 131.70 ?  3   ARG   A HH11 1 
ATOM   4922  H  HH12 . ARG   B 1 4   ? 48.435  11.662  94.679  1.00 131.70 ?  3   ARG   A HH12 1 
ATOM   4923  H  HH21 . ARG   B 1 4   ? 50.155  9.389   96.328  1.00 83.99  ?  3   ARG   A HH21 1 
ATOM   4924  H  HH22 . ARG   B 1 4   ? 49.855  10.846  96.267  1.00 83.99  ?  3   ARG   A HH22 1 
ATOM   4925  N  N    . THR   B 1 5   ? 44.379  3.733   92.411  1.00 59.71  ?  4   THR   A N    1 
ATOM   4926  C  CA   . THR   B 1 5   ? 43.781  2.916   91.361  1.00 54.62  ?  4   THR   A CA   1 
ATOM   4927  C  C    . THR   B 1 5   ? 42.803  3.745   90.537  1.00 54.00  ?  4   THR   A C    1 
ATOM   4928  O  O    . THR   B 1 5   ? 42.313  4.791   90.984  1.00 53.22  ?  4   THR   A O    1 
ATOM   4929  C  CB   . THR   B 1 5   ? 43.032  1.715   91.931  1.00 51.23  ?  4   THR   A CB   1 
ATOM   4930  O  OG1  . THR   B 1 5   ? 41.926  2.211   92.689  1.00 42.93  ?  4   THR   A OG1  1 
ATOM   4931  C  CG2  . THR   B 1 5   ? 43.922  0.862   92.799  1.00 58.68  ?  4   THR   A CG2  1 
ATOM   4932  H  H    . THR   B 1 5   ? 43.816  4.221   92.840  1.00 71.66  ?  4   THR   A H    1 
ATOM   4933  H  HA   . THR   B 1 5   ? 44.496  2.610   90.782  1.00 65.54  ?  4   THR   A HA   1 
ATOM   4934  H  HB   . THR   B 1 5   ? 42.721  1.140   91.214  1.00 61.47  ?  4   THR   A HB   1 
ATOM   4935  H  HG1  . THR   B 1 5   ? 41.543  1.577   93.086  1.00 51.52  ?  4   THR   A HG1  1 
ATOM   4936  H  HG21 . THR   B 1 5   ? 43.416  0.121   93.166  1.00 70.42  ?  4   THR   A HG21 1 
ATOM   4937  H  HG22 . THR   B 1 5   ? 44.659  0.512   92.275  1.00 70.42  ?  4   THR   A HG22 1 
ATOM   4938  H  HG23 . THR   B 1 5   ? 44.278  1.392   93.529  1.00 70.42  ?  4   THR   A HG23 1 
ATOM   4939  N  N    . ILE   B 1 6   ? 42.498  3.233   89.329  1.00 52.67  ?  5   ILE   A N    1 
ATOM   4940  C  CA   . ILE   B 1 6   ? 41.407  3.741   88.501  1.00 49.61  ?  5   ILE   A CA   1 
ATOM   4941  C  C    . ILE   B 1 6   ? 40.555  2.563   88.043  1.00 48.12  ?  5   ILE   A C    1 
ATOM   4942  O  O    . ILE   B 1 6   ? 40.991  1.406   88.055  1.00 48.71  ?  5   ILE   A O    1 
ATOM   4943  C  CB   . ILE   B 1 6   ? 41.894  4.521   87.256  1.00 47.01  ?  5   ILE   A CB   1 
ATOM   4944  C  CG1  . ILE   B 1 6   ? 42.923  3.678   86.493  1.00 47.82  ?  5   ILE   A CG1  1 
ATOM   4945  C  CG2  . ILE   B 1 6   ? 42.454  5.860   87.621  1.00 49.97  ?  5   ILE   A CG2  1 
ATOM   4946  C  CD1  . ILE   B 1 6   ? 43.402  4.297   85.197  1.00 46.57  ?  5   ILE   A CD1  1 
ATOM   4947  H  H    . ILE   B 1 6   ? 42.922  2.577   88.968  1.00 63.20  ?  5   ILE   A H    1 
ATOM   4948  H  HA   . ILE   B 1 6   ? 40.873  4.340   89.047  1.00 59.53  ?  5   ILE   A HA   1 
ATOM   4949  H  HB   . ILE   B 1 6   ? 41.129  4.684   86.683  1.00 56.41  ?  5   ILE   A HB   1 
ATOM   4950  H  HG12 . ILE   B 1 6   ? 43.699  3.549   87.060  1.00 57.38  ?  5   ILE   A HG12 1 
ATOM   4951  H  HG13 . ILE   B 1 6   ? 42.523  2.821   86.278  1.00 57.38  ?  5   ILE   A HG13 1 
ATOM   4952  H  HG21 . ILE   B 1 6   ? 42.675  6.342   86.808  1.00 59.97  ?  5   ILE   A HG21 1 
ATOM   4953  H  HG22 . ILE   B 1 6   ? 41.790  6.353   88.127  1.00 59.97  ?  5   ILE   A HG22 1 
ATOM   4954  H  HG23 . ILE   B 1 6   ? 43.252  5.733   88.158  1.00 59.97  ?  5   ILE   A HG23 1 
ATOM   4955  H  HD11 . ILE   B 1 6   ? 43.998  3.675   84.751  1.00 55.89  ?  5   ILE   A HD11 1 
ATOM   4956  H  HD12 . ILE   B 1 6   ? 42.635  4.482   84.633  1.00 55.89  ?  5   ILE   A HD12 1 
ATOM   4957  H  HD13 . ILE   B 1 6   ? 43.872  5.122   85.396  1.00 55.89  ?  5   ILE   A HD13 1 
ATOM   4958  N  N    . LYS   B 1 7   ? 39.334  2.875   87.599  1.00 49.50  ?  6   LYS   A N    1 
ATOM   4959  C  CA   . LYS   B 1 7   ? 38.431  1.895   87.000  1.00 46.16  ?  6   LYS   A CA   1 
ATOM   4960  C  C    . LYS   B 1 7   ? 38.469  2.096   85.488  1.00 39.40  ?  6   LYS   A C    1 
ATOM   4961  O  O    . LYS   B 1 7   ? 38.360  3.229   85.003  1.00 39.03  ?  6   LYS   A O    1 
ATOM   4962  C  CB   . LYS   B 1 7   ? 37.013  2.049   87.542  1.00 51.36  ?  6   LYS   A CB   1 
ATOM   4963  C  CG   . LYS   B 1 7   ? 36.558  0.950   88.529  1.00 57.80  ?  6   LYS   A CG   1 
ATOM   4964  C  CD   . LYS   B 1 7   ? 35.527  1.495   89.548  1.00 66.06  ?  6   LYS   A CD   1 
ATOM   4965  C  CE   . LYS   B 1 7   ? 34.467  0.462   89.935  1.00 79.45  ?  6   LYS   A CE   1 
ATOM   4966  N  NZ   . LYS   B 1 7   ? 33.217  1.121   90.447  1.00 62.38  ?  6   LYS   A NZ   1 
ATOM   4967  H  H    . LYS   B 1 7   ? 39.001  3.667   87.637  1.00 59.41  ?  6   LYS   A H    1 
ATOM   4968  H  HA   . LYS   B 1 7   ? 38.714  0.991   87.208  1.00 55.39  ?  6   LYS   A HA   1 
ATOM   4969  H  HB2  . LYS   B 1 7   ? 36.955  2.898   88.007  1.00 61.63  ?  6   LYS   A HB2  1 
ATOM   4970  H  HB3  . LYS   B 1 7   ? 36.397  2.038   86.793  1.00 61.63  ?  6   LYS   A HB3  1 
ATOM   4971  H  HG2  . LYS   B 1 7   ? 36.144  0.226   88.034  1.00 69.36  ?  6   LYS   A HG2  1 
ATOM   4972  H  HG3  . LYS   B 1 7   ? 37.327  0.620   89.020  1.00 69.36  ?  6   LYS   A HG3  1 
ATOM   4973  H  HD2  . LYS   B 1 7   ? 35.993  1.762   90.356  1.00 79.27  ?  6   LYS   A HD2  1 
ATOM   4974  H  HD3  . LYS   B 1 7   ? 35.072  2.259   89.160  1.00 79.27  ?  6   LYS   A HD3  1 
ATOM   4975  H  HE2  . LYS   B 1 7   ? 34.235  -0.067  89.156  1.00 95.34  ?  6   LYS   A HE2  1 
ATOM   4976  H  HE3  . LYS   B 1 7   ? 34.818  -0.112  90.633  1.00 95.34  ?  6   LYS   A HE3  1 
ATOM   4977  H  HZ1  . LYS   B 1 7   ? 32.615  0.503   90.666  1.00 74.85  ?  6   LYS   A HZ1  1 
ATOM   4978  H  HZ2  . LYS   B 1 7   ? 33.403  1.610   91.167  1.00 74.85  ?  6   LYS   A HZ2  1 
ATOM   4979  H  HZ3  . LYS   B 1 7   ? 32.872  1.651   89.820  1.00 74.85  ?  6   LYS   A HZ3  1 
ATOM   4980  N  N    . VAL   B 1 8   ? 38.714  1.017   84.747  1.00 38.69  ?  7   VAL   A N    1 
ATOM   4981  C  CA   . VAL   B 1 8   ? 38.650  1.053   83.289  1.00 42.47  ?  7   VAL   A CA   1 
ATOM   4982  C  C    . VAL   B 1 8   ? 37.820  -0.121  82.796  1.00 38.01  ?  7   VAL   A C    1 
ATOM   4983  O  O    . VAL   B 1 8   ? 37.457  -1.027  83.556  1.00 40.88  ?  7   VAL   A O    1 
ATOM   4984  C  CB   . VAL   B 1 8   ? 40.048  1.019   82.634  1.00 31.59  ?  7   VAL   A CB   1 
ATOM   4985  C  CG1  . VAL   B 1 8   ? 40.899  2.107   83.225  1.00 39.02  ?  7   VAL   A CG1  1 
ATOM   4986  C  CG2  . VAL   B 1 8   ? 40.644  -0.371  82.781  1.00 35.13  ?  7   VAL   A CG2  1 
ATOM   4987  H  H    . VAL   B 1 8   ? 38.921  0.247   85.070  1.00 46.43  ?  7   VAL   A H    1 
ATOM   4988  H  HA   . VAL   B 1 8   ? 38.204  1.873   83.025  1.00 50.96  ?  7   VAL   A HA   1 
ATOM   4989  H  HB   . VAL   B 1 8   ? 39.999  1.194   81.681  1.00 37.90  ?  7   VAL   A HB   1 
ATOM   4990  H  HG11 . VAL   B 1 8   ? 41.610  2.325   82.603  1.00 46.82  ?  7   VAL   A HG11 1 
ATOM   4991  H  HG12 . VAL   B 1 8   ? 40.347  2.889   83.383  1.00 46.82  ?  7   VAL   A HG12 1 
ATOM   4992  H  HG13 . VAL   B 1 8   ? 41.276  1.794   84.062  1.00 46.82  ?  7   VAL   A HG13 1 
ATOM   4993  H  HG21 . VAL   B 1 8   ? 41.606  -0.315  82.671  1.00 42.16  ?  7   VAL   A HG21 1 
ATOM   4994  H  HG22 . VAL   B 1 8   ? 40.430  -0.714  83.662  1.00 42.16  ?  7   VAL   A HG22 1 
ATOM   4995  H  HG23 . VAL   B 1 8   ? 40.267  -0.949  82.100  1.00 42.16  ?  7   VAL   A HG23 1 
ATOM   4996  N  N    . PHE   B 1 9   ? 37.544  -0.117  81.499  1.00 37.16  ?  8   PHE   A N    1 
ATOM   4997  C  CA   . PHE   B 1 9   ? 36.892  -1.264  80.880  1.00 40.97  ?  8   PHE   A CA   1 
ATOM   4998  C  C    . PHE   B 1 9   ? 37.848  -1.999  79.947  1.00 37.62  ?  8   PHE   A C    1 
ATOM   4999  O  O    . PHE   B 1 9   ? 38.652  -1.379  79.249  1.00 32.16  ?  8   PHE   A O    1 
ATOM   5000  C  CB   . PHE   B 1 9   ? 35.662  -0.878  80.065  1.00 43.16  ?  8   PHE   A CB   1 
ATOM   5001  C  CG   . PHE   B 1 9   ? 34.632  -0.083  80.819  1.00 35.13  ?  8   PHE   A CG   1 
ATOM   5002  C  CD1  . PHE   B 1 9   ? 33.641  -0.708  81.512  1.00 35.22  ?  8   PHE   A CD1  1 
ATOM   5003  C  CD2  . PHE   B 1 9   ? 34.626  1.289   80.752  1.00 39.55  ?  8   PHE   A CD2  1 
ATOM   5004  C  CE1  . PHE   B 1 9   ? 32.706  0.014   82.169  1.00 39.07  ?  8   PHE   A CE1  1 
ATOM   5005  C  CE2  . PHE   B 1 9   ? 33.685  2.018   81.404  1.00 32.89  ?  8   PHE   A CE2  1 
ATOM   5006  C  CZ   . PHE   B 1 9   ? 32.739  1.384   82.132  1.00 41.19  ?  8   PHE   A CZ   1 
ATOM   5007  H  H    . PHE   B 1 9   ? 37.723  0.531   80.962  1.00 44.60  ?  8   PHE   A H    1 
ATOM   5008  H  HA   . PHE   B 1 9   ? 36.620  -1.852  81.602  1.00 49.16  ?  8   PHE   A HA   1 
ATOM   5009  H  HB2  . PHE   B 1 9   ? 35.949  -0.341  79.310  1.00 51.80  ?  8   PHE   A HB2  1 
ATOM   5010  H  HB3  . PHE   B 1 9   ? 35.233  -1.689  79.752  1.00 51.80  ?  8   PHE   A HB3  1 
ATOM   5011  H  HD1  . PHE   B 1 9   ? 33.606  -1.637  81.533  1.00 42.26  ?  8   PHE   A HD1  1 
ATOM   5012  H  HD2  . PHE   B 1 9   ? 35.277  1.725   80.251  1.00 47.46  ?  8   PHE   A HD2  1 
ATOM   5013  H  HE1  . PHE   B 1 9   ? 32.037  -0.420  82.647  1.00 46.88  ?  8   PHE   A HE1  1 
ATOM   5014  H  HE2  . PHE   B 1 9   ? 33.690  2.947   81.350  1.00 39.47  ?  8   PHE   A HE2  1 
ATOM   5015  H  HZ   . PHE   B 1 9   ? 32.111  1.877   82.609  1.00 49.43  ?  8   PHE   A HZ   1 
ATOM   5016  N  N    . THR   B 1 10  ? 37.741  -3.321  79.926  1.00 35.34  ?  9   THR   A N    1 
ATOM   5017  C  CA   . THR   B 1 10  ? 38.464  -4.146  78.980  1.00 31.20  ?  9   THR   A CA   1 
ATOM   5018  C  C    . THR   B 1 10  ? 37.461  -4.913  78.119  1.00 37.25  ?  9   THR   A C    1 
ATOM   5019  O  O    . THR   B 1 10  ? 36.286  -5.072  78.468  1.00 37.41  ?  9   THR   A O    1 
ATOM   5020  C  CB   . THR   B 1 10  ? 39.454  -5.099  79.697  1.00 31.84  ?  9   THR   A CB   1 
ATOM   5021  O  OG1  . THR   B 1 10  ? 38.774  -6.010  80.561  1.00 38.22  ?  9   THR   A OG1  1 
ATOM   5022  C  CG2  . THR   B 1 10  ? 40.390  -4.296  80.492  1.00 36.57  ?  9   THR   A CG2  1 
ATOM   5023  H  H    . THR   B 1 10  ? 37.243  -3.770  80.465  1.00 42.41  ?  9   THR   A H    1 
ATOM   5024  H  HA   . THR   B 1 10  ? 38.996  -3.594  78.386  1.00 37.44  ?  9   THR   A HA   1 
ATOM   5025  H  HB   . THR   B 1 10  ? 39.933  -5.621  79.035  1.00 38.21  ?  9   THR   A HB   1 
ATOM   5026  H  HG1  . THR   B 1 10  ? 38.093  -6.316  80.176  1.00 45.87  ?  9   THR   A HG1  1 
ATOM   5027  H  HG21 . THR   B 1 10  ? 40.936  -4.875  81.046  1.00 43.88  ?  9   THR   A HG21 1 
ATOM   5028  H  HG22 . THR   B 1 10  ? 40.968  -3.784  79.906  1.00 43.88  ?  9   THR   A HG22 1 
ATOM   5029  H  HG23 . THR   B 1 10  ? 39.900  -3.684  81.063  1.00 43.88  ?  9   THR   A HG23 1 
ATOM   5030  N  N    . THR   B 1 11  ? 37.936  -5.374  76.973  1.00 30.98  ?  10  THR   A N    1 
ATOM   5031  C  CA   . THR   B 1 11  ? 37.054  -5.923  75.964  1.00 34.93  ?  10  THR   A CA   1 
ATOM   5032  C  C    . THR   B 1 11  ? 37.927  -6.640  74.949  1.00 37.84  ?  10  THR   A C    1 
ATOM   5033  O  O    . THR   B 1 11  ? 39.092  -6.317  74.779  1.00 34.92  ?  10  THR   A O    1 
ATOM   5034  C  CB   . THR   B 1 11  ? 36.224  -4.820  75.297  1.00 30.85  ?  10  THR   A CB   1 
ATOM   5035  O  OG1  . THR   B 1 11  ? 35.196  -5.412  74.490  1.00 33.23  ?  10  THR   A OG1  1 
ATOM   5036  C  CG2  . THR   B 1 11  ? 37.161  -3.904  74.481  1.00 38.39  ?  10  THR   A CG2  1 
ATOM   5037  H  H    . THR   B 1 11  ? 38.768  -5.378  76.757  1.00 37.17  ?  10  THR   A H    1 
ATOM   5038  H  HA   . THR   B 1 11  ? 36.440  -6.565  76.355  1.00 41.92  ?  10  THR   A HA   1 
ATOM   5039  H  HB   . THR   B 1 11  ? 35.780  -4.262  75.955  1.00 37.02  ?  10  THR   A HB   1 
ATOM   5040  H  HG1  . THR   B 1 11  ? 34.880  -6.087  74.878  1.00 39.87  ?  10  THR   A HG1  1 
ATOM   5041  H  HG21 . THR   B 1 11  ? 36.686  -3.104  74.207  1.00 46.07  ?  10  THR   A HG21 1 
ATOM   5042  H  HG22 . THR   B 1 11  ? 37.926  -3.648  75.019  1.00 46.07  ?  10  THR   A HG22 1 
ATOM   5043  H  HG23 . THR   B 1 11  ? 37.474  -4.371  73.690  1.00 46.07  ?  10  THR   A HG23 1 
ATOM   5044  N  N    . VAL   B 1 12  ? 37.338  -7.600  74.262  1.00 42.16  ?  11  VAL   A N    1 
ATOM   5045  C  CA   . VAL   B 1 12  ? 37.936  -8.126  73.046  1.00 40.97  ?  11  VAL   A CA   1 
ATOM   5046  C  C    . VAL   B 1 12  ? 37.188  -7.716  71.797  1.00 43.68  ?  11  VAL   A C    1 
ATOM   5047  O  O    . VAL   B 1 12  ? 37.710  -7.935  70.694  1.00 43.83  ?  11  VAL   A O    1 
ATOM   5048  C  CB   . VAL   B 1 12  ? 38.041  -9.660  73.092  1.00 41.40  ?  11  VAL   A CB   1 
ATOM   5049  C  CG1  . VAL   B 1 12  ? 39.157  -10.057 74.012  1.00 50.45  ?  11  VAL   A CG1  1 
ATOM   5050  C  CG2  . VAL   B 1 12  ? 36.725  -10.241 73.553  1.00 46.06  ?  11  VAL   A CG2  1 
ATOM   5051  H  H    . VAL   B 1 12  ? 36.590  -7.965  74.478  1.00 50.60  ?  11  VAL   A H    1 
ATOM   5052  H  HA   . VAL   B 1 12  ? 38.834  -7.766  72.982  1.00 49.17  ?  11  VAL   A HA   1 
ATOM   5053  H  HB   . VAL   B 1 12  ? 38.236  -10.012 72.209  1.00 49.68  ?  11  VAL   A HB   1 
ATOM   5054  H  HG11 . VAL   B 1 12  ? 39.193  -11.024 74.066  1.00 60.54  ?  11  VAL   A HG11 1 
ATOM   5055  H  HG12 . VAL   B 1 12  ? 39.993  -9.714  73.661  1.00 60.54  ?  11  VAL   A HG12 1 
ATOM   5056  H  HG13 . VAL   B 1 12  ? 38.989  -9.682  74.891  1.00 60.54  ?  11  VAL   A HG13 1 
ATOM   5057  H  HG21 . VAL   B 1 12  ? 36.786  -11.209 73.544  1.00 55.27  ?  11  VAL   A HG21 1 
ATOM   5058  H  HG22 . VAL   B 1 12  ? 36.541  -9.929  74.453  1.00 55.27  ?  11  VAL   A HG22 1 
ATOM   5059  H  HG23 . VAL   B 1 12  ? 36.022  -9.948  72.952  1.00 55.27  ?  11  VAL   A HG23 1 
ATOM   5060  N  N    . ASP   B 1 13  ? 36.005  -7.104  71.924  1.00 40.52  ?  12  ASP   A N    1 
ATOM   5061  C  CA   . ASP   B 1 13  ? 35.140  -6.831  70.794  1.00 31.67  ?  12  ASP   A CA   1 
ATOM   5062  C  C    . ASP   B 1 13  ? 34.500  -5.449  70.790  1.00 38.88  ?  12  ASP   A C    1 
ATOM   5063  O  O    . ASP   B 1 13  ? 33.846  -5.085  69.794  1.00 35.66  ?  12  ASP   A O    1 
ATOM   5064  C  CB   . ASP   B 1 13  ? 34.028  -7.884  70.781  1.00 37.09  ?  12  ASP   A CB   1 
ATOM   5065  C  CG   . ASP   B 1 13  ? 33.248  -7.949  72.121  1.00 45.32  ?  12  ASP   A CG   1 
ATOM   5066  O  OD1  . ASP   B 1 13  ? 32.514  -8.982  72.305  1.00 40.08  ?  12  ASP   A OD1  1 
ATOM   5067  O  OD2  . ASP   B 1 13  ? 33.363  -6.973  72.953  1.00 36.39  ?  12  ASP   A OD2  1 
ATOM   5068  H  H    . ASP   B 1 13  ? 35.682  -6.835  72.674  1.00 48.62  ?  12  ASP   A H    1 
ATOM   5069  H  HA   . ASP   B 1 13  ? 35.657  -6.891  69.976  1.00 38.00  ?  12  ASP   A HA   1 
ATOM   5070  H  HB2  . ASP   B 1 13  ? 33.396  -7.668  70.077  1.00 44.51  ?  12  ASP   A HB2  1 
ATOM   5071  H  HB3  . ASP   B 1 13  ? 34.420  -8.756  70.619  1.00 44.51  ?  12  ASP   A HB3  1 
ATOM   5072  N  N    . ASN   B 1 14  ? 34.664  -4.679  71.859  1.00 36.24  ?  13  ASN   A N    1 
ATOM   5073  C  CA   . ASN   B 1 14  ? 34.058  -3.367  72.059  1.00 36.02  ?  13  ASN   A CA   1 
ATOM   5074  C  C    . ASN   B 1 14  ? 32.526  -3.406  72.087  1.00 33.91  ?  13  ASN   A C    1 
ATOM   5075  O  O    . ASN   B 1 14  ? 31.859  -2.383  71.950  1.00 37.22  ?  13  ASN   A O    1 
ATOM   5076  C  CB   . ASN   B 1 14  ? 34.536  -2.370  71.020  1.00 31.31  ?  13  ASN   A CB   1 
ATOM   5077  C  CG   . ASN   B 1 14  ? 34.642  -0.997  71.578  1.00 39.33  ?  13  ASN   A CG   1 
ATOM   5078  O  OD1  . ASN   B 1 14  ? 34.263  -0.762  72.696  1.00 48.65  ?  13  ASN   A OD1  1 
ATOM   5079  N  ND2  . ASN   B 1 14  ? 35.187  -0.089  70.822  1.00 43.78  ?  13  ASN   A ND2  1 
ATOM   5080  H  H    . ASN   B 1 14  ? 35.154  -4.910  72.527  1.00 43.49  ?  13  ASN   A H    1 
ATOM   5081  H  HA   . ASN   B 1 14  ? 34.343  -3.052  72.931  1.00 43.23  ?  13  ASN   A HA   1 
ATOM   5082  H  HB2  . ASN   B 1 14  ? 35.412  -2.636  70.700  1.00 37.57  ?  13  ASN   A HB2  1 
ATOM   5083  H  HB3  . ASN   B 1 14  ? 33.906  -2.350  70.282  1.00 37.57  ?  13  ASN   A HB3  1 
ATOM   5084  H  HD21 . ASN   B 1 14  ? 35.467  -0.296  70.035  1.00 52.54  ?  13  ASN   A HD21 1 
ATOM   5085  H  HD22 . ASN   B 1 14  ? 35.267  0.718   71.108  1.00 52.54  ?  13  ASN   A HD22 1 
ATOM   5086  N  N    . ILE   B 1 15  ? 31.924  -4.559  72.316  1.00 32.31  ?  14  ILE   A N    1 
ATOM   5087  C  CA   . ILE   B 1 15  ? 30.483  -4.656  72.469  1.00 40.52  ?  14  ILE   A CA   1 
ATOM   5088  C  C    . ILE   B 1 15  ? 30.113  -5.246  73.828  1.00 37.18  ?  14  ILE   A C    1 
ATOM   5089  O  O    . ILE   B 1 15  ? 29.211  -4.744  74.506  1.00 35.29  ?  14  ILE   A O    1 
ATOM   5090  C  CB   . ILE   B 1 15  ? 29.863  -5.471  71.306  1.00 36.64  ?  14  ILE   A CB   1 
ATOM   5091  C  CG1  . ILE   B 1 15  ? 28.443  -5.948  71.633  1.00 51.66  ?  14  ILE   A CG1  1 
ATOM   5092  C  CG2  . ILE   B 1 15  ? 30.737  -6.656  70.981  1.00 37.84  ?  14  ILE   A CG2  1 
ATOM   5093  C  CD1  . ILE   B 1 15  ? 27.721  -6.539  70.399  1.00 65.51  ?  14  ILE   A CD1  1 
ATOM   5094  H  H    . ILE   B 1 15  ? 32.335  -5.311  72.389  1.00 38.77  ?  14  ILE   A H    1 
ATOM   5095  H  HA   . ILE   B 1 15  ? 30.091  -3.769  72.433  1.00 48.63  ?  14  ILE   A HA   1 
ATOM   5096  H  HB   . ILE   B 1 15  ? 29.809  -4.882  70.538  1.00 43.96  ?  14  ILE   A HB   1 
ATOM   5097  H  HG12 . ILE   B 1 15  ? 28.488  -6.636  72.315  1.00 61.99  ?  14  ILE   A HG12 1 
ATOM   5098  H  HG13 . ILE   B 1 15  ? 27.922  -5.195  71.955  1.00 61.99  ?  14  ILE   A HG13 1 
ATOM   5099  H  HG21 . ILE   B 1 15  ? 30.334  -7.154  70.252  1.00 45.41  ?  14  ILE   A HG21 1 
ATOM   5100  H  HG22 . ILE   B 1 15  ? 31.615  -6.339  70.719  1.00 45.41  ?  14  ILE   A HG22 1 
ATOM   5101  H  HG23 . ILE   B 1 15  ? 30.809  -7.220  71.767  1.00 45.41  ?  14  ILE   A HG23 1 
ATOM   5102  H  HD11 . ILE   B 1 15  ? 26.831  -6.823  70.660  1.00 78.62  ?  14  ILE   A HD11 1 
ATOM   5103  H  HD12 . ILE   B 1 15  ? 27.662  -5.858  69.711  1.00 78.62  ?  14  ILE   A HD12 1 
ATOM   5104  H  HD13 . ILE   B 1 15  ? 28.228  -7.298  70.071  1.00 78.62  ?  14  ILE   A HD13 1 
ATOM   5105  N  N    . ASN   B 1 16  ? 30.891  -6.214  74.292  1.00 36.15  ?  15  ASN   A N    1 
ATOM   5106  C  CA   . ASN   B 1 16  ? 30.913  -6.625  75.692  1.00 37.52  ?  15  ASN   A CA   1 
ATOM   5107  C  C    . ASN   B 1 16  ? 32.061  -5.958  76.457  1.00 39.97  ?  15  ASN   A C    1 
ATOM   5108  O  O    . ASN   B 1 16  ? 33.229  -6.341  76.300  1.00 36.36  ?  15  ASN   A O    1 
ATOM   5109  C  CB   . ASN   B 1 16  ? 31.046  -8.140  75.741  1.00 42.12  ?  15  ASN   A CB   1 
ATOM   5110  C  CG   . ASN   B 1 16  ? 29.772  -8.830  75.371  1.00 49.59  ?  15  ASN   A CG   1 
ATOM   5111  O  OD1  . ASN   B 1 16  ? 28.689  -8.360  75.722  1.00 44.43  ?  15  ASN   A OD1  1 
ATOM   5112  N  ND2  . ASN   B 1 16  ? 29.883  -9.948  74.661  1.00 50.65  ?  15  ASN   A ND2  1 
ATOM   5113  H  H    . ASN   B 1 16  ? 31.435  -6.664  73.800  1.00 43.38  ?  15  ASN   A H    1 
ATOM   5114  H  HA   . ASN   B 1 16  ? 30.095  -6.328  76.121  1.00 45.02  ?  15  ASN   A HA   1 
ATOM   5115  H  HB2  . ASN   B 1 16  ? 31.734  -8.419  75.117  1.00 50.55  ?  15  ASN   A HB2  1 
ATOM   5116  H  HB3  . ASN   B 1 16  ? 31.286  -8.409  76.642  1.00 50.55  ?  15  ASN   A HB3  1 
ATOM   5117  H  HD21 . ASN   B 1 16  ? 30.660  -10.240 74.437  1.00 60.78  ?  15  ASN   A HD21 1 
ATOM   5118  H  HD22 . ASN   B 1 16  ? 29.177  -10.379 74.425  1.00 60.78  ?  15  ASN   A HD22 1 
ATOM   5119  N  N    . LEU   B 1 17  ? 31.712  -5.024  77.350  1.00 38.39  ?  16  LEU   A N    1 
ATOM   5120  C  CA   . LEU   B 1 17  ? 32.671  -4.374  78.232  1.00 34.49  ?  16  LEU   A CA   1 
ATOM   5121  C  C    . LEU   B 1 17  ? 32.729  -5.045  79.591  1.00 37.74  ?  16  LEU   A C    1 
ATOM   5122  O  O    . LEU   B 1 17  ? 31.690  -5.404  80.154  1.00 34.79  ?  16  LEU   A O    1 
ATOM   5123  C  CB   . LEU   B 1 17  ? 32.309  -2.910  78.454  1.00 35.74  ?  16  LEU   A CB   1 
ATOM   5124  C  CG   . LEU   B 1 17  ? 32.133  -2.089  77.175  1.00 43.74  ?  16  LEU   A CG   1 
ATOM   5125  C  CD1  . LEU   B 1 17  ? 32.121  -0.603  77.482  1.00 43.54  ?  16  LEU   A CD1  1 
ATOM   5126  C  CD2  . LEU   B 1 17  ? 33.248  -2.359  76.160  1.00 37.86  ?  16  LEU   A CD2  1 
ATOM   5127  H  H    . LEU   B 1 17  ? 30.905  -4.748  77.462  1.00 46.06  ?  16  LEU   A H    1 
ATOM   5128  H  HA   . LEU   B 1 17  ? 33.541  -4.439  77.810  1.00 41.39  ?  16  LEU   A HA   1 
ATOM   5129  H  HB2  . LEU   B 1 17  ? 31.472  -2.871  78.943  1.00 42.88  ?  16  LEU   A HB2  1 
ATOM   5130  H  HB3  . LEU   B 1 17  ? 33.016  -2.494  78.972  1.00 42.88  ?  16  LEU   A HB3  1 
ATOM   5131  H  HG   . LEU   B 1 17  ? 31.285  -2.354  76.785  1.00 52.49  ?  16  LEU   A HG   1 
ATOM   5132  H  HD11 . LEU   B 1 17  ? 31.866  -0.117  76.682  1.00 52.25  ?  16  LEU   A HD11 1 
ATOM   5133  H  HD12 . LEU   B 1 17  ? 31.482  -0.432  78.191  1.00 52.25  ?  16  LEU   A HD12 1 
ATOM   5134  H  HD13 . LEU   B 1 17  ? 33.009  -0.332  77.764  1.00 52.25  ?  16  LEU   A HD13 1 
ATOM   5135  H  HD21 . LEU   B 1 17  ? 33.302  -1.611  75.544  1.00 45.43  ?  16  LEU   A HD21 1 
ATOM   5136  H  HD22 . LEU   B 1 17  ? 34.088  -2.460  76.633  1.00 45.43  ?  16  LEU   A HD22 1 
ATOM   5137  H  HD23 . LEU   B 1 17  ? 33.042  -3.173  75.674  1.00 45.43  ?  16  LEU   A HD23 1 
ATOM   5138  N  N    . HIS   B 1 18  ? 33.951  -5.157  80.133  1.00 40.58  ?  17  HIS   A N    1 
ATOM   5139  C  CA   . HIS   B 1 18  ? 34.216  -5.789  81.426  1.00 41.90  ?  17  HIS   A CA   1 
ATOM   5140  C  C    . HIS   B 1 18  ? 34.976  -4.844  82.335  1.00 33.74  ?  17  HIS   A C    1 
ATOM   5141  O  O    . HIS   B 1 18  ? 36.124  -4.494  82.032  1.00 36.89  ?  17  HIS   A O    1 
ATOM   5142  C  CB   . HIS   B 1 18  ? 35.043  -7.068  81.255  1.00 42.06  ?  17  HIS   A CB   1 
ATOM   5143  C  CG   . HIS   B 1 18  ? 34.467  -8.032  80.273  1.00 39.22  ?  17  HIS   A CG   1 
ATOM   5144  N  ND1  . HIS   B 1 18  ? 33.713  -9.118  80.656  1.00 46.49  ?  17  HIS   A ND1  1 
ATOM   5145  C  CD2  . HIS   B 1 18  ? 34.520  -8.070  78.921  1.00 43.19  ?  17  HIS   A CD2  1 
ATOM   5146  C  CE1  . HIS   B 1 18  ? 33.325  -9.786  79.583  1.00 50.97  ?  17  HIS   A CE1  1 
ATOM   5147  N  NE2  . HIS   B 1 18  ? 33.814  -9.178  78.516  1.00 46.16  ?  17  HIS   A NE2  1 
ATOM   5148  H  H    . HIS   B 1 18  ? 34.664  -4.862  79.754  1.00 48.69  ?  17  HIS   A H    1 
ATOM   5149  H  HA   . HIS   B 1 18  ? 33.360  -5.990  81.835  1.00 50.28  ?  17  HIS   A HA   1 
ATOM   5150  H  HB2  . HIS   B 1 18  ? 35.930  -6.827  80.946  1.00 50.47  ?  17  HIS   A HB2  1 
ATOM   5151  H  HB3  . HIS   B 1 18  ? 35.101  -7.518  82.112  1.00 50.47  ?  17  HIS   A HB3  1 
ATOM   5152  H  HD2  . HIS   B 1 18  ? 34.954  -7.461  78.369  1.00 51.83  ?  17  HIS   A HD2  1 
ATOM   5153  H  HE1  . HIS   B 1 18  ? 32.798  -10.553 79.579  1.00 61.17  ?  17  HIS   A HE1  1 
ATOM   5154  H  HE2  . HIS   B 1 18  ? 33.708  -9.434  77.702  1.00 55.39  ?  17  HIS   A HE2  1 
ATOM   5155  N  N    . THR   B 1 19  ? 34.355  -4.462  83.453  1.00 35.90  ?  18  THR   A N    1 
ATOM   5156  C  CA   . THR   B 1 19  ? 34.953  -3.468  84.340  1.00 40.36  ?  18  THR   A CA   1 
ATOM   5157  C  C    . THR   B 1 19  ? 36.161  -4.051  85.070  1.00 40.59  ?  18  THR   A C    1 
ATOM   5158  O  O    . THR   B 1 19  ? 36.113  -5.186  85.554  1.00 43.43  ?  18  THR   A O    1 
ATOM   5159  C  CB   . THR   B 1 19  ? 33.950  -2.977  85.392  1.00 43.54  ?  18  THR   A CB   1 
ATOM   5160  O  OG1  . THR   B 1 19  ? 32.886  -2.222  84.790  1.00 44.86  ?  18  THR   A OG1  1 
ATOM   5161  C  CG2  . THR   B 1 19  ? 34.689  -2.096  86.427  1.00 48.18  ?  18  THR   A CG2  1 
ATOM   5162  H  H    . THR   B 1 19  ? 33.594  -4.761  83.717  1.00 43.07  ?  18  THR   A H    1 
ATOM   5163  H  HA   . THR   B 1 19  ? 35.228  -2.713  83.796  1.00 48.43  ?  18  THR   A HA   1 
ATOM   5164  H  HB   . THR   B 1 19  ? 33.551  -3.741  85.837  1.00 52.25  ?  18  THR   A HB   1 
ATOM   5165  H  HG1  . THR   B 1 19  ? 32.399  -1.885  85.386  1.00 53.83  ?  18  THR   A HG1  1 
ATOM   5166  H  HG21 . THR   B 1 19  ? 34.059  -1.749  87.077  1.00 57.82  ?  18  THR   A HG21 1 
ATOM   5167  H  HG22 . THR   B 1 19  ? 35.362  -2.621  86.889  1.00 57.82  ?  18  THR   A HG22 1 
ATOM   5168  H  HG23 . THR   B 1 19  ? 35.123  -1.353  85.980  1.00 57.82  ?  18  THR   A HG23 1 
ATOM   5169  N  N    . GLN   B 1 20  ? 37.212  -3.244  85.206  1.00 36.74  ?  19  GLN   A N    1 
ATOM   5170  C  CA   . GLN   B 1 20  ? 38.433  -3.628  85.899  1.00 42.99  ?  19  GLN   A CA   1 
ATOM   5171  C  C    . GLN   B 1 20  ? 38.865  -2.490  86.822  1.00 49.93  ?  19  GLN   A C    1 
ATOM   5172  O  O    . GLN   B 1 20  ? 38.542  -1.315  86.592  1.00 48.71  ?  19  GLN   A O    1 
ATOM   5173  C  CB   . GLN   B 1 20  ? 39.579  -3.922  84.924  1.00 41.10  ?  19  GLN   A CB   1 
ATOM   5174  C  CG   . GLN   B 1 20  ? 39.255  -4.935  83.857  1.00 45.03  ?  19  GLN   A CG   1 
ATOM   5175  C  CD   . GLN   B 1 20  ? 39.036  -6.338  84.394  1.00 43.56  ?  19  GLN   A CD   1 
ATOM   5176  O  OE1  . GLN   B 1 20  ? 39.477  -6.686  85.483  1.00 46.91  ?  19  GLN   A OE1  1 
ATOM   5177  N  NE2  . GLN   B 1 20  ? 38.365  -7.154  83.610  1.00 44.56  ?  19  GLN   A NE2  1 
ATOM   5178  H  H    . GLN   B 1 20  ? 37.240  -2.444  84.894  1.00 44.09  ?  19  GLN   A H    1 
ATOM   5179  H  HA   . GLN   B 1 20  ? 38.259  -4.425  86.424  1.00 51.58  ?  19  GLN   A HA   1 
ATOM   5180  H  HB2  . GLN   B 1 20  ? 39.823  -3.096  84.478  1.00 49.32  ?  19  GLN   A HB2  1 
ATOM   5181  H  HB3  . GLN   B 1 20  ? 40.333  -4.262  85.429  1.00 49.32  ?  19  GLN   A HB3  1 
ATOM   5182  H  HG2  . GLN   B 1 20  ? 38.442  -4.661  83.403  1.00 54.03  ?  19  GLN   A HG2  1 
ATOM   5183  H  HG3  . GLN   B 1 20  ? 39.991  -4.970  83.226  1.00 54.03  ?  19  GLN   A HG3  1 
ATOM   5184  H  HE21 . GLN   B 1 20  ? 38.081  -6.879  82.847  1.00 53.47  ?  19  GLN   A HE21 1 
ATOM   5185  H  HE22 . GLN   B 1 20  ? 38.211  -7.961  83.862  1.00 53.47  ?  19  GLN   A HE22 1 
ATOM   5186  N  N    . VAL   B 1 21  ? 39.592  -2.849  87.876  1.00 53.35  ?  20  VAL   A N    1 
ATOM   5187  C  CA   . VAL   B 1 21  ? 40.326  -1.895  88.699  1.00 52.97  ?  20  VAL   A CA   1 
ATOM   5188  C  C    . VAL   B 1 21  ? 41.789  -2.104  88.386  1.00 51.69  ?  20  VAL   A C    1 
ATOM   5189  O  O    . VAL   B 1 21  ? 42.260  -3.245  88.338  1.00 49.43  ?  20  VAL   A O    1 
ATOM   5190  C  CB   . VAL   B 1 21  ? 40.070  -2.069  90.204  1.00 65.23  ?  20  VAL   A CB   1 
ATOM   5191  C  CG1  . VAL   B 1 21  ? 40.889  -3.207  90.769  1.00 67.08  ?  20  VAL   A CG1  1 
ATOM   5192  C  CG2  . VAL   B 1 21  ? 40.416  -0.769  90.930  1.00 66.60  ?  20  VAL   A CG2  1 
ATOM   5193  H  H    . VAL   B 1 21  ? 39.676  -3.663  88.141  1.00 64.02  ?  20  VAL   A H    1 
ATOM   5194  H  HA   . VAL   B 1 21  ? 40.049  -0.995  88.470  1.00 63.56  ?  20  VAL   A HA   1 
ATOM   5195  H  HB   . VAL   B 1 21  ? 39.133  -2.280  90.342  1.00 78.27  ?  20  VAL   A HB   1 
ATOM   5196  H  HG11 . VAL   B 1 21  ? 40.613  -3.372  91.684  1.00 80.50  ?  20  VAL   A HG11 1 
ATOM   5197  H  HG12 . VAL   B 1 21  ? 40.741  -4.001  90.231  1.00 80.50  ?  20  VAL   A HG12 1 
ATOM   5198  H  HG13 . VAL   B 1 21  ? 41.828  -2.963  90.746  1.00 80.50  ?  20  VAL   A HG13 1 
ATOM   5199  H  HG21 . VAL   B 1 21  ? 40.256  -0.885  91.880  1.00 79.92  ?  20  VAL   A HG21 1 
ATOM   5200  H  HG22 . VAL   B 1 21  ? 41.351  -0.560  90.775  1.00 79.92  ?  20  VAL   A HG22 1 
ATOM   5201  H  HG23 . VAL   B 1 21  ? 39.856  -0.056  90.585  1.00 79.92  ?  20  VAL   A HG23 1 
ATOM   5202  N  N    . VAL   B 1 22  ? 42.500  -1.013  88.160  1.00 53.25  ?  21  VAL   A N    1 
ATOM   5203  C  CA   . VAL   B 1 22  ? 43.878  -1.053  87.720  1.00 50.25  ?  21  VAL   A CA   1 
ATOM   5204  C  C    . VAL   B 1 22  ? 44.729  -0.358  88.766  1.00 47.38  ?  21  VAL   A C    1 
ATOM   5205  O  O    . VAL   B 1 22  ? 44.593  0.853   88.966  1.00 45.58  ?  21  VAL   A O    1 
ATOM   5206  C  CB   . VAL   B 1 22  ? 44.057  -0.363  86.359  1.00 50.59  ?  21  VAL   A CB   1 
ATOM   5207  C  CG1  . VAL   B 1 22  ? 45.326  -0.831  85.681  1.00 59.49  ?  21  VAL   A CG1  1 
ATOM   5208  C  CG2  . VAL   B 1 22  ? 42.855  -0.602  85.486  1.00 55.15  ?  21  VAL   A CG2  1 
ATOM   5209  H  H    . VAL   B 1 22  ? 42.195  -0.215  88.258  1.00 63.90  ?  21  VAL   A H    1 
ATOM   5210  H  HA   . VAL   B 1 22  ? 44.159  -1.979  87.650  1.00 60.30  ?  21  VAL   A HA   1 
ATOM   5211  H  HB   . VAL   B 1 22  ? 44.138  0.593   86.500  1.00 60.70  ?  21  VAL   A HB   1 
ATOM   5212  H  HG11 . VAL   B 1 22  ? 45.416  -0.375  84.830  1.00 71.38  ?  21  VAL   A HG11 1 
ATOM   5213  H  HG12 . VAL   B 1 22  ? 46.083  -0.622  86.250  1.00 71.38  ?  21  VAL   A HG12 1 
ATOM   5214  H  HG13 . VAL   B 1 22  ? 45.273  -1.789  85.539  1.00 71.38  ?  21  VAL   A HG13 1 
ATOM   5215  H  HG21 . VAL   B 1 22  ? 43.002  -0.181  84.624  1.00 66.18  ?  21  VAL   A HG21 1 
ATOM   5216  H  HG22 . VAL   B 1 22  ? 42.733  -1.557  85.371  1.00 66.18  ?  21  VAL   A HG22 1 
ATOM   5217  H  HG23 . VAL   B 1 22  ? 42.073  -0.217  85.913  1.00 66.18  ?  21  VAL   A HG23 1 
ATOM   5218  N  N    . ASP   B 1 23  ? 45.734  -1.064  89.291  1.00 60.25  ?  22  ASP   A N    1 
ATOM   5219  C  CA   . ASP   B 1 23  ? 46.755  -0.505  90.142  1.00 57.22  ?  22  ASP   A CA   1 
ATOM   5220  C  C    . ASP   B 1 23  ? 47.557  0.432   89.296  1.00 49.66  ?  22  ASP   A C    1 
ATOM   5221  O  O    . ASP   B 1 23  ? 48.065  0.020   88.318  1.00 50.88  ?  22  ASP   A O    1 
ATOM   5222  C  CB   . ASP   B 1 23  ? 47.667  -1.613  90.655  1.00 70.08  ?  22  ASP   A CB   1 
ATOM   5223  C  CG   . ASP   B 1 23  ? 48.418  -1.234  91.923  1.00 73.24  ?  22  ASP   A CG   1 
ATOM   5224  O  OD1  . ASP   B 1 23  ? 48.155  -1.833  92.970  1.00 83.39  ?  22  ASP   A OD1  1 
ATOM   5225  O  OD2  . ASP   B 1 23  ? 49.290  -0.369  91.872  1.00 73.88  ?  22  ASP   A OD2  1 
ATOM   5226  H  H    . ASP   B 1 23  ? 45.900  -1.909  89.242  1.00 72.30  ?  22  ASP   A H    1 
ATOM   5227  H  HA   . ASP   B 1 23  ? 46.465  -0.066  90.905  1.00 68.67  ?  22  ASP   A HA   1 
ATOM   5228  H  HB2  . ASP   B 1 23  ? 47.129  -2.397  90.850  1.00 84.10  ?  22  ASP   A HB2  1 
ATOM   5229  H  HB3  . ASP   B 1 23  ? 48.322  -1.823  89.971  1.00 84.10  ?  22  ASP   A HB3  1 
ATOM   5230  N  N    . MET   B 1 24  ? 47.772  1.675   89.714  1.00 46.77  ?  23  MET   A N    1 
ATOM   5231  C  CA   . MET   B 1 24  ? 48.575  2.622   88.949  1.00 48.82  ?  23  MET   A CA   1 
ATOM   5232  C  C    . MET   B 1 24  ? 50.060  2.436   89.158  1.00 56.76  ?  23  MET   A C    1 
ATOM   5233  O  O    . MET   B 1 24  ? 50.850  3.043   88.476  1.00 53.96  ?  23  MET   A O    1 
ATOM   5234  C  CB   . MET   B 1 24  ? 48.194  4.051   89.268  1.00 46.88  ?  23  MET   A CB   1 
ATOM   5235  C  CG   . MET   B 1 24  ? 46.726  4.280   89.129  1.00 55.38  ?  23  MET   A CG   1 
ATOM   5236  S  SD   . MET   B 1 24  ? 46.140  5.950   89.267  1.00 61.08  ?  23  MET   A SD   1 
ATOM   5237  C  CE   . MET   B 1 24  ? 46.816  6.617   87.771  1.00 56.49  ?  23  MET   A CE   1 
ATOM   5238  H  H    . MET   B 1 24  ? 47.479  2.038   90.437  1.00 56.13  ?  23  MET   A H    1 
ATOM   5239  H  HA   . MET   B 1 24  ? 48.391  2.489   88.001  1.00 58.58  ?  23  MET   A HA   1 
ATOM   5240  H  HB2  . MET   B 1 24  ? 48.448  4.252   90.183  1.00 56.25  ?  23  MET   A HB2  1 
ATOM   5241  H  HB3  . MET   B 1 24  ? 48.654  4.646   88.656  1.00 56.25  ?  23  MET   A HB3  1 
ATOM   5242  H  HG2  . MET   B 1 24  ? 46.431  3.930   88.274  1.00 66.46  ?  23  MET   A HG2  1 
ATOM   5243  H  HG3  . MET   B 1 24  ? 46.331  3.789   89.835  1.00 66.46  ?  23  MET   A HG3  1 
ATOM   5244  H  HE1  . MET   B 1 24  ? 46.647  7.562   87.745  1.00 67.78  ?  23  MET   A HE1  1 
ATOM   5245  H  HE2  . MET   B 1 24  ? 47.762  6.452   87.755  1.00 67.78  ?  23  MET   A HE2  1 
ATOM   5246  H  HE3  . MET   B 1 24  ? 46.396  6.188   87.022  1.00 67.78  ?  23  MET   A HE3  1 
ATOM   5247  N  N    . SER   B 1 25  ? 50.421  1.602   90.126  1.00 57.97  ?  24  SER   A N    1 
ATOM   5248  C  CA   . SER   B 1 25  ? 51.742  1.212   90.401  1.00 61.07  ?  24  SER   A CA   1 
ATOM   5249  C  C    . SER   B 1 25  ? 52.015  -0.199  89.942  1.00 64.44  ?  24  SER   A C    1 
ATOM   5250  O  O    . SER   B 1 25  ? 52.788  -0.845  90.594  1.00 71.40  ?  24  SER   A O    1 
ATOM   5251  C  CB   . SER   B 1 25  ? 52.027  1.320   91.888  1.00 81.13  ?  24  SER   A CB   1 
ATOM   5252  O  OG   . SER   B 1 25  ? 51.669  0.144   92.581  1.00 83.97  ?  24  SER   A OG   1 
ATOM   5253  H  H    . SER   B 1 25  ? 49.905  1.292   90.731  1.00 69.57  ?  24  SER   A H    1 
ATOM   5254  H  HA   . SER   B 1 25  ? 52.348  1.825   89.941  1.00 73.29  ?  24  SER   A HA   1 
ATOM   5255  H  HB2  . SER   B 1 25  ? 52.976  1.478   92.012  1.00 97.35  ?  24  SER   A HB2  1 
ATOM   5256  H  HB3  . SER   B 1 25  ? 51.521  2.063   92.252  1.00 97.35  ?  24  SER   A HB3  1 
ATOM   5257  H  HG   . SER   B 1 25  ? 51.337  0.336   93.306  1.00 100.76 ?  24  SER   A HG   1 
ATOM   5258  N  N    . MET   B 1 26  ? 51.660  -0.497  88.672  1.00 64.27  ?  25  MET   A N    1 
ATOM   5259  C  CA   . MET   B 1 26  ? 51.916  -1.721  87.888  1.00 58.18  ?  25  MET   A CA   1 
ATOM   5260  C  C    . MET   B 1 26  ? 51.602  -1.327  86.414  1.00 49.95  ?  25  MET   A C    1 
ATOM   5261  O  O    . MET   B 1 26  ? 50.733  -0.542  86.206  1.00 57.96  ?  25  MET   A O    1 
ATOM   5262  C  CB   . MET   B 1 26  ? 51.019  -2.876  88.305  1.00 57.82  ?  25  MET   A CB   1 
ATOM   5263  C  CG   . MET   B 1 26  ? 51.321  -3.510  89.643  1.00 64.75  ?  25  MET   A CG   1 
ATOM   5264  S  SD   . MET   B 1 26  ? 50.478  -5.013  89.995  1.00 71.94  ?  25  MET   A SD   1 
ATOM   5265  C  CE   . MET   B 1 26  ? 49.371  -4.573  91.296  1.00 63.60  ?  25  MET   A CE   1 
ATOM   5266  H  H    . MET   B 1 26  ? 51.258  0.032   88.149  1.00 77.12  ?  25  MET   A H    1 
ATOM   5267  H  HA   . MET   B 1 26  ? 52.854  -1.991  87.976  1.00 69.81  ?  25  MET   A HA   1 
ATOM   5268  H  HB2  . MET   B 1 26  ? 50.105  -2.554  88.340  1.00 69.38  ?  25  MET   A HB2  1 
ATOM   5269  H  HB3  . MET   B 1 26  ? 51.088  -3.574  87.635  1.00 69.38  ?  25  MET   A HB3  1 
ATOM   5270  H  HG2  . MET   B 1 26  ? 52.274  -3.684  89.697  1.00 77.70  ?  25  MET   A HG2  1 
ATOM   5271  H  HG3  . MET   B 1 26  ? 51.060  -2.899  90.346  1.00 77.70  ?  25  MET   A HG3  1 
ATOM   5272  H  HE1  . MET   B 1 26  ? 49.292  -5.315  91.899  1.00 76.32  ?  25  MET   A HE1  1 
ATOM   5273  H  HE2  . MET   B 1 26  ? 49.725  -3.814  91.759  1.00 76.32  ?  25  MET   A HE2  1 
ATOM   5274  H  HE3  . MET   B 1 26  ? 48.513  -4.371  90.918  1.00 76.32  ?  25  MET   A HE3  1 
ATOM   5275  N  N    . THR   B 1 27  ? 52.261  -1.847  85.384  1.00 49.27  ?  26  THR   A N    1 
ATOM   5276  C  CA   . THR   B 1 27  ? 51.912  -1.474  83.993  1.00 55.67  ?  26  THR   A CA   1 
ATOM   5277  C  C    . THR   B 1 27  ? 50.711  -2.265  83.483  1.00 54.45  ?  26  THR   A C    1 
ATOM   5278  O  O    . THR   B 1 27  ? 50.334  -3.207  84.149  1.00 56.89  ?  26  THR   A O    1 
ATOM   5279  C  CB   . THR   B 1 27  ? 53.057  -1.710  83.011  1.00 52.45  ?  26  THR   A CB   1 
ATOM   5280  O  OG1  . THR   B 1 27  ? 53.296  -3.098  82.857  1.00 54.07  ?  26  THR   A OG1  1 
ATOM   5281  C  CG2  . THR   B 1 27  ? 54.283  -1.084  83.491  1.00 57.61  ?  26  THR   A CG2  1 
ATOM   5282  H  H    . THR   B 1 27  ? 52.909  -2.408  85.449  1.00 59.12  ?  26  THR   A H    1 
ATOM   5283  H  HA   . THR   B 1 27  ? 51.681  -0.523  83.967  1.00 66.80  ?  26  THR   A HA   1 
ATOM   5284  H  HB   . THR   B 1 27  ? 52.831  -1.323  82.150  1.00 62.95  ?  26  THR   A HB   1 
ATOM   5285  H  HG1  . THR   B 1 27  ? 54.023  -3.218  82.498  1.00 64.89  ?  26  THR   A HG1  1 
ATOM   5286  H  HG21 . THR   B 1 27  ? 55.040  -1.441  83.021  1.00 69.13  ?  26  THR   A HG21 1 
ATOM   5287  H  HG22 . THR   B 1 27  ? 54.245  -0.136  83.347  1.00 69.13  ?  26  THR   A HG22 1 
ATOM   5288  H  HG23 . THR   B 1 27  ? 54.390  -1.253  84.430  1.00 69.13  ?  26  THR   A HG23 1 
ATOM   5289  N  N    . TYR   B 1 28  ? 50.069  -1.956  82.360  1.00 50.62  ?  27  TYR   A N    1 
ATOM   5290  C  CA   . TYR   B 1 28  ? 48.914  -2.775  81.976  1.00 50.42  ?  27  TYR   A CA   1 
ATOM   5291  C  C    . TYR   B 1 28  ? 49.353  -4.202  81.673  1.00 52.45  ?  27  TYR   A C    1 
ATOM   5292  O  O    . TYR   B 1 28  ? 48.642  -5.169  81.994  1.00 46.26  ?  27  TYR   A O    1 
ATOM   5293  C  CB   . TYR   B 1 28  ? 48.196  -2.189  80.748  1.00 45.07  ?  27  TYR   A CB   1 
ATOM   5294  C  CG   . TYR   B 1 28  ? 47.490  -0.893  81.021  1.00 41.20  ?  27  TYR   A CG   1 
ATOM   5295  C  CD1  . TYR   B 1 28  ? 46.264  -0.878  81.655  1.00 44.04  ?  27  TYR   A CD1  1 
ATOM   5296  C  CD2  . TYR   B 1 28  ? 48.050  0.314   80.642  1.00 47.57  ?  27  TYR   A CD2  1 
ATOM   5297  C  CE1  . TYR   B 1 28  ? 45.619  0.304   81.918  1.00 38.49  ?  27  TYR   A CE1  1 
ATOM   5298  C  CE2  . TYR   B 1 28  ? 47.416  1.498   80.909  1.00 47.71  ?  27  TYR   A CE2  1 
ATOM   5299  C  CZ   . TYR   B 1 28  ? 46.202  1.487   81.539  1.00 44.26  ?  27  TYR   A CZ   1 
ATOM   5300  O  OH   . TYR   B 1 28  ? 45.577  2.682   81.792  1.00 38.66  ?  27  TYR   A OH   1 
ATOM   5301  H  H    . TYR   B 1 28  ? 50.314  -1.373  81.776  1.00 60.74  ?  27  TYR   A H    1 
ATOM   5302  H  HA   . TYR   B 1 28  ? 48.284  -2.774  82.713  1.00 60.50  ?  27  TYR   A HA   1 
ATOM   5303  H  HB2  . TYR   B 1 28  ? 48.852  -2.028  80.051  1.00 54.08  ?  27  TYR   A HB2  1 
ATOM   5304  H  HB3  . TYR   B 1 28  ? 47.534  -2.828  80.440  1.00 54.08  ?  27  TYR   A HB3  1 
ATOM   5305  H  HD1  . TYR   B 1 28  ? 45.869  -1.681  81.908  1.00 52.85  ?  27  TYR   A HD1  1 
ATOM   5306  H  HD2  . TYR   B 1 28  ? 48.867  0.321   80.199  1.00 57.08  ?  27  TYR   A HD2  1 
ATOM   5307  H  HE1  . TYR   B 1 28  ? 44.795  0.303   82.350  1.00 46.19  ?  27  TYR   A HE1  1 
ATOM   5308  H  HE2  . TYR   B 1 28  ? 47.809  2.305   80.665  1.00 57.25  ?  27  TYR   A HE2  1 
ATOM   5309  H  HH   . TYR   B 1 28  ? 46.148  3.289   81.900  1.00 46.39  ?  27  TYR   A HH   1 
ATOM   5310  N  N    . GLY   B 1 29  ? 50.528  -4.345  81.034  1.00 50.16  ?  28  GLY   A N    1 
ATOM   5311  C  CA   . GLY   B 1 29  ? 51.044  -5.671  80.728  1.00 51.19  ?  28  GLY   A CA   1 
ATOM   5312  C  C    . GLY   B 1 29  ? 51.043  -6.583  81.940  1.00 46.64  ?  28  GLY   A C    1 
ATOM   5313  O  O    . GLY   B 1 29  ? 50.782  -7.780  81.840  1.00 50.25  ?  28  GLY   A O    1 
ATOM   5314  H  H    . GLY   B 1 29  ? 51.030  -3.697  80.776  1.00 60.20  ?  28  GLY   A H    1 
ATOM   5315  H  HA2  . GLY   B 1 29  ? 50.497  -6.078  80.039  1.00 61.42  ?  28  GLY   A HA2  1 
ATOM   5316  H  HA3  . GLY   B 1 29  ? 51.955  -5.595  80.404  1.00 61.42  ?  28  GLY   A HA3  1 
ATOM   5317  N  N    . GLN   B 1 30  ? 51.343  -6.032  83.103  1.00 49.24  ?  29  GLN   A N    1 
ATOM   5318  C  CA   . GLN   B 1 30  ? 51.487  -6.871  84.283  1.00 50.02  ?  29  GLN   A CA   1 
ATOM   5319  C  C    . GLN   B 1 30  ? 50.159  -7.282  84.870  1.00 51.18  ?  29  GLN   A C    1 
ATOM   5320  O  O    . GLN   B 1 30  ? 50.105  -8.302  85.557  1.00 62.84  ?  29  GLN   A O    1 
ATOM   5321  C  CB   . GLN   B 1 30  ? 52.318  -6.152  85.331  1.00 52.93  ?  29  GLN   A CB   1 
ATOM   5322  C  CG   . GLN   B 1 30  ? 53.665  -5.686  84.729  1.00 62.02  ?  29  GLN   A CG   1 
ATOM   5323  C  CD   . GLN   B 1 30  ? 54.642  -5.147  85.774  1.00 63.26  ?  29  GLN   A CD   1 
ATOM   5324  O  OE1  . GLN   B 1 30  ? 54.387  -4.124  86.424  1.00 54.72  ?  29  GLN   A OE1  1 
ATOM   5325  N  NE2  . GLN   B 1 30  ? 55.778  -5.826  85.922  1.00 73.15  ?  29  GLN   A NE2  1 
ATOM   5326  H  H    . GLN   B 1 30  ? 51.466  -5.191  83.236  1.00 59.08  ?  29  GLN   A H    1 
ATOM   5327  H  HA   . GLN   B 1 30  ? 51.959  -7.682  84.036  1.00 60.02  ?  29  GLN   A HA   1 
ATOM   5328  H  HB2  . GLN   B 1 30  ? 51.834  -5.373  85.649  1.00 63.51  ?  29  GLN   A HB2  1 
ATOM   5329  H  HB3  . GLN   B 1 30  ? 52.500  -6.753  86.069  1.00 63.51  ?  29  GLN   A HB3  1 
ATOM   5330  H  HG2  . GLN   B 1 30  ? 54.088  -6.438  84.286  1.00 74.42  ?  29  GLN   A HG2  1 
ATOM   5331  H  HG3  . GLN   B 1 30  ? 53.494  -4.978  84.088  1.00 74.42  ?  29  GLN   A HG3  1 
ATOM   5332  H  HE21 . GLN   B 1 30  ? 55.927  -6.524  85.442  1.00 87.78  ?  29  GLN   A HE21 1 
ATOM   5333  H  HE22 . GLN   B 1 30  ? 56.362  -5.566  86.496  1.00 87.78  ?  29  GLN   A HE22 1 
ATOM   5334  N  N    . GLN   B 1 31  ? 49.091  -6.530  84.603  1.00 53.30  ?  30  GLN   A N    1 
ATOM   5335  C  CA   . GLN   B 1 31  ? 47.753  -6.864  85.072  1.00 52.35  ?  30  GLN   A CA   1 
ATOM   5336  C  C    . GLN   B 1 31  ? 46.910  -7.546  84.012  1.00 51.75  ?  30  GLN   A C    1 
ATOM   5337  O  O    . GLN   B 1 31  ? 46.016  -8.318  84.364  1.00 47.97  ?  30  GLN   A O    1 
ATOM   5338  C  CB   . GLN   B 1 31  ? 47.037  -5.598  85.547  1.00 47.05  ?  30  GLN   A CB   1 
ATOM   5339  C  CG   . GLN   B 1 31  ? 47.678  -4.969  86.769  1.00 52.14  ?  30  GLN   A CG   1 
ATOM   5340  C  CD   . GLN   B 1 31  ? 47.585  -3.449  86.789  1.00 51.88  ?  30  GLN   A CD   1 
ATOM   5341  O  OE1  . GLN   B 1 31  ? 46.726  -2.897  87.460  1.00 51.74  ?  30  GLN   A OE1  1 
ATOM   5342  N  NE2  . GLN   B 1 31  ? 48.497  -2.767  86.093  1.00 51.09  ?  30  GLN   A NE2  1 
ATOM   5343  H  H    . GLN   B 1 31  ? 49.120  -5.804  84.142  1.00 63.96  ?  30  GLN   A H    1 
ATOM   5344  H  HA   . GLN   B 1 31  ? 47.822  -7.468  85.828  1.00 62.82  ?  30  GLN   A HA   1 
ATOM   5345  H  HB2  . GLN   B 1 31  ? 47.052  -4.942  84.832  1.00 56.46  ?  30  GLN   A HB2  1 
ATOM   5346  H  HB3  . GLN   B 1 31  ? 46.121  -5.822  85.772  1.00 56.46  ?  30  GLN   A HB3  1 
ATOM   5347  H  HG2  . GLN   B 1 31  ? 47.233  -5.304  87.563  1.00 62.56  ?  30  GLN   A HG2  1 
ATOM   5348  H  HG3  . GLN   B 1 31  ? 48.618  -5.210  86.789  1.00 62.56  ?  30  GLN   A HG3  1 
ATOM   5349  H  HE21 . GLN   B 1 31  ? 49.107  -3.187  85.656  1.00 61.31  ?  30  GLN   A HE21 1 
ATOM   5350  H  HE22 . GLN   B 1 31  ? 48.475  -1.907  86.082  1.00 61.31  ?  30  GLN   A HE22 1 
ATOM   5351  N  N    . PHE   B 1 32  ? 47.208  -7.314  82.721  1.00 50.21  ?  31  PHE   A N    1 
ATOM   5352  C  CA   . PHE   B 1 32  ? 46.305  -7.704  81.658  1.00 46.77  ?  31  PHE   A CA   1 
ATOM   5353  C  C    . PHE   B 1 32  ? 46.962  -8.437  80.504  1.00 53.65  ?  31  PHE   A C    1 
ATOM   5354  O  O    . PHE   B 1 32  ? 46.271  -8.768  79.531  1.00 59.63  ?  31  PHE   A O    1 
ATOM   5355  C  CB   . PHE   B 1 32  ? 45.614  -6.464  81.076  1.00 46.32  ?  31  PHE   A CB   1 
ATOM   5356  C  CG   . PHE   B 1 32  ? 44.784  -5.712  82.058  1.00 54.62  ?  31  PHE   A CG   1 
ATOM   5357  C  CD1  . PHE   B 1 32  ? 44.208  -6.349  83.147  1.00 51.60  ?  31  PHE   A CD1  1 
ATOM   5358  C  CD2  . PHE   B 1 32  ? 44.524  -4.363  81.872  1.00 57.71  ?  31  PHE   A CD2  1 
ATOM   5359  C  CE1  . PHE   B 1 32  ? 43.435  -5.643  84.041  1.00 51.47  ?  31  PHE   A CE1  1 
ATOM   5360  C  CE2  . PHE   B 1 32  ? 43.724  -3.658  82.784  1.00 57.24  ?  31  PHE   A CE2  1 
ATOM   5361  C  CZ   . PHE   B 1 32  ? 43.194  -4.300  83.856  1.00 47.55  ?  31  PHE   A CZ   1 
ATOM   5362  H  H    . PHE   B 1 32  ? 47.929  -6.932  82.449  1.00 60.25  ?  31  PHE   A H    1 
ATOM   5363  H  HA   . PHE   B 1 32  ? 45.644  -8.297  82.047  1.00 56.12  ?  31  PHE   A HA   1 
ATOM   5364  H  HB2  . PHE   B 1 32  ? 46.294  -5.859  80.740  1.00 55.59  ?  31  PHE   A HB2  1 
ATOM   5365  H  HB3  . PHE   B 1 32  ? 45.032  -6.744  80.352  1.00 55.59  ?  31  PHE   A HB3  1 
ATOM   5366  H  HD1  . PHE   B 1 32  ? 44.345  -7.260  83.274  1.00 61.92  ?  31  PHE   A HD1  1 
ATOM   5367  H  HD2  . PHE   B 1 32  ? 44.884  -3.921  81.136  1.00 69.26  ?  31  PHE   A HD2  1 
ATOM   5368  H  HE1  . PHE   B 1 32  ? 43.073  -6.078  84.779  1.00 61.77  ?  31  PHE   A HE1  1 
ATOM   5369  H  HE2  . PHE   B 1 32  ? 43.557  -2.752  82.654  1.00 68.68  ?  31  PHE   A HE2  1 
ATOM   5370  H  HZ   . PHE   B 1 32  ? 42.668  -3.833  84.465  1.00 57.06  ?  31  PHE   A HZ   1 
ATOM   5371  N  N    . GLY   B 1 33  ? 48.268  -8.639  80.541  1.00 52.51  ?  32  GLY   A N    1 
ATOM   5372  C  CA   . GLY   B 1 33  ? 48.973  -9.108  79.378  1.00 54.68  ?  32  GLY   A CA   1 
ATOM   5373  C  C    . GLY   B 1 33  ? 48.943  -8.038  78.310  1.00 52.69  ?  32  GLY   A C    1 
ATOM   5374  O  O    . GLY   B 1 33  ? 48.755  -6.852  78.603  1.00 53.50  ?  32  GLY   A O    1 
ATOM   5375  H  H    . GLY   B 1 33  ? 48.764  -8.511  81.232  1.00 63.02  ?  32  GLY   A H    1 
ATOM   5376  H  HA2  . GLY   B 1 33  ? 49.895  -9.307  79.605  1.00 65.62  ?  32  GLY   A HA2  1 
ATOM   5377  H  HA3  . GLY   B 1 33  ? 48.552  -9.912  79.036  1.00 65.62  ?  32  GLY   A HA3  1 
ATOM   5378  N  N    . PRO   B 1 34  ? 49.152  -8.432  77.055  1.00 55.50  ?  33  PRO   A N    1 
ATOM   5379  C  CA   . PRO   B 1 34  ? 49.042  -7.474  75.943  1.00 56.10  ?  33  PRO   A CA   1 
ATOM   5380  C  C    . PRO   B 1 34  ? 47.732  -6.698  75.958  1.00 54.87  ?  33  PRO   A C    1 
ATOM   5381  O  O    . PRO   B 1 34  ? 46.638  -7.271  76.051  1.00 47.51  ?  33  PRO   A O    1 
ATOM   5382  C  CB   . PRO   B 1 34  ? 49.147  -8.362  74.701  1.00 54.93  ?  33  PRO   A CB   1 
ATOM   5383  C  CG   . PRO   B 1 34  ? 50.012  -9.516  75.174  1.00 62.97  ?  33  PRO   A CG   1 
ATOM   5384  C  CD   . PRO   B 1 34  ? 49.708  -9.732  76.634  1.00 54.90  ?  33  PRO   A CD   1 
ATOM   5385  H  HA   . PRO   B 1 34  ? 49.782  -6.848  75.978  1.00 67.33  ?  33  PRO   A HA   1 
ATOM   5386  H  HB2  . PRO   B 1 34  ? 48.268  -8.668  74.429  1.00 65.92  ?  33  PRO   A HB2  1 
ATOM   5387  H  HB3  . PRO   B 1 34  ? 49.570  -7.878  73.975  1.00 65.92  ?  33  PRO   A HB3  1 
ATOM   5388  H  HG2  . PRO   B 1 34  ? 49.796  -10.311 74.661  1.00 75.57  ?  33  PRO   A HG2  1 
ATOM   5389  H  HG3  . PRO   B 1 34  ? 50.947  -9.287  75.053  1.00 75.57  ?  33  PRO   A HG3  1 
ATOM   5390  H  HD2  . PRO   B 1 34  ? 49.056  -10.441 76.750  1.00 65.88  ?  33  PRO   A HD2  1 
ATOM   5391  H  HD3  . PRO   B 1 34  ? 50.516  -9.940  77.129  1.00 65.88  ?  33  PRO   A HD3  1 
ATOM   5392  N  N    . THR   B 1 35  ? 47.863  -5.380  75.834  1.00 52.16  ?  34  THR   A N    1 
ATOM   5393  C  CA   . THR   B 1 35  ? 46.776  -4.449  76.064  1.00 45.53  ?  34  THR   A CA   1 
ATOM   5394  C  C    . THR   B 1 35  ? 46.915  -3.286  75.099  1.00 49.45  ?  34  THR   A C    1 
ATOM   5395  O  O    . THR   B 1 35  ? 48.038  -2.851  74.824  1.00 47.87  ?  34  THR   A O    1 
ATOM   5396  C  CB   . THR   B 1 35  ? 46.785  -3.916  77.495  1.00 46.87  ?  34  THR   A CB   1 
ATOM   5397  O  OG1  . THR   B 1 35  ? 46.470  -4.980  78.404  1.00 51.34  ?  34  THR   A OG1  1 
ATOM   5398  C  CG2  . THR   B 1 35  ? 45.762  -2.786  77.600  1.00 45.90  ?  34  THR   A CG2  1 
ATOM   5399  H  H    . THR   B 1 35  ? 48.598  -4.993  75.611  1.00 62.59  ?  34  THR   A H    1 
ATOM   5400  H  HA   . THR   B 1 35  ? 45.931  -4.898  75.902  1.00 54.64  ?  34  THR   A HA   1 
ATOM   5401  H  HB   . THR   B 1 35  ? 47.657  -3.568  77.738  1.00 56.24  ?  34  THR   A HB   1 
ATOM   5402  H  HG1  . THR   B 1 35  ? 47.044  -5.590  78.343  1.00 61.60  ?  34  THR   A HG1  1 
ATOM   5403  H  HG21 . THR   B 1 35  ? 45.703  -2.476  78.518  1.00 55.08  ?  34  THR   A HG21 1 
ATOM   5404  H  HG22 . THR   B 1 35  ? 46.028  -2.044  77.035  1.00 55.08  ?  34  THR   A HG22 1 
ATOM   5405  H  HG23 . THR   B 1 35  ? 44.889  -3.100  77.317  1.00 55.08  ?  34  THR   A HG23 1 
ATOM   5406  N  N    . TYR   B 1 36  ? 45.779  -2.757  74.630  1.00 38.68  ?  35  TYR   A N    1 
ATOM   5407  C  CA   . TYR   B 1 36  ? 45.775  -1.684  73.648  1.00 37.48  ?  35  TYR   A CA   1 
ATOM   5408  C  C    . TYR   B 1 36  ? 44.675  -0.672  73.942  1.00 40.37  ?  35  TYR   A C    1 
ATOM   5409  O  O    . TYR   B 1 36  ? 43.599  -1.005  74.462  1.00 36.75  ?  35  TYR   A O    1 
ATOM   5410  C  CB   . TYR   B 1 36  ? 45.596  -2.246  72.241  1.00 40.39  ?  35  TYR   A CB   1 
ATOM   5411  C  CG   . TYR   B 1 36  ? 46.542  -3.392  71.833  1.00 42.51  ?  35  TYR   A CG   1 
ATOM   5412  C  CD1  . TYR   B 1 36  ? 47.637  -3.163  70.992  1.00 45.20  ?  35  TYR   A CD1  1 
ATOM   5413  C  CD2  . TYR   B 1 36  ? 46.299  -4.698  72.242  1.00 45.93  ?  35  TYR   A CD2  1 
ATOM   5414  C  CE1  . TYR   B 1 36  ? 48.476  -4.204  70.578  1.00 45.53  ?  35  TYR   A CE1  1 
ATOM   5415  C  CE2  . TYR   B 1 36  ? 47.132  -5.756  71.841  1.00 48.67  ?  35  TYR   A CE2  1 
ATOM   5416  C  CZ   . TYR   B 1 36  ? 48.226  -5.502  71.013  1.00 53.48  ?  35  TYR   A CZ   1 
ATOM   5417  O  OH   . TYR   B 1 36  ? 49.043  -6.553  70.627  1.00 50.49  ?  35  TYR   A OH   1 
ATOM   5418  H  H    . TYR   B 1 36  ? 44.993  -3.009  74.873  1.00 46.42  ?  35  TYR   A H    1 
ATOM   5419  H  HA   . TYR   B 1 36  ? 46.616  -1.204  73.705  1.00 44.97  ?  35  TYR   A HA   1 
ATOM   5420  H  HB2  . TYR   B 1 36  ? 44.690  -2.584  72.165  1.00 48.47  ?  35  TYR   A HB2  1 
ATOM   5421  H  HB3  . TYR   B 1 36  ? 45.735  -1.524  71.609  1.00 48.47  ?  35  TYR   A HB3  1 
ATOM   5422  H  HD1  . TYR   B 1 36  ? 47.811  -2.297  70.700  1.00 54.24  ?  35  TYR   A HD1  1 
ATOM   5423  H  HD2  . TYR   B 1 36  ? 45.570  -4.875  72.792  1.00 55.11  ?  35  TYR   A HD2  1 
ATOM   5424  H  HE1  . TYR   B 1 36  ? 49.196  -4.030  70.016  1.00 54.63  ?  35  TYR   A HE1  1 
ATOM   5425  H  HE2  . TYR   B 1 36  ? 46.954  -6.623  72.126  1.00 58.40  ?  35  TYR   A HE2  1 
ATOM   5426  H  HH   . TYR   B 1 36  ? 48.752  -7.274  70.945  1.00 60.58  ?  35  TYR   A HH   1 
ATOM   5427  N  N    . LEU   B 1 37  ? 44.962  0.577   73.602  1.00 36.43  ?  36  LEU   A N    1 
ATOM   5428  C  CA   . LEU   B 1 37  ? 44.012  1.677   73.747  1.00 39.86  ?  36  LEU   A CA   1 
ATOM   5429  C  C    . LEU   B 1 37  ? 43.904  2.394   72.401  1.00 46.02  ?  36  LEU   A C    1 
ATOM   5430  O  O    . LEU   B 1 37  ? 44.853  3.062   71.967  1.00 43.98  ?  36  LEU   A O    1 
ATOM   5431  C  CB   . LEU   B 1 37  ? 44.453  2.657   74.829  1.00 32.94  ?  36  LEU   A CB   1 
ATOM   5432  C  CG   . LEU   B 1 37  ? 43.760  4.002   74.902  1.00 34.61  ?  36  LEU   A CG   1 
ATOM   5433  C  CD1  . LEU   B 1 37  ? 42.327  3.763   75.271  1.00 44.13  ?  36  LEU   A CD1  1 
ATOM   5434  C  CD2  . LEU   B 1 37  ? 44.465  4.897   75.935  1.00 41.49  ?  36  LEU   A CD2  1 
ATOM   5435  H  H    . LEU   B 1 37  ? 45.720  0.821   73.277  1.00 43.72  ?  36  LEU   A H    1 
ATOM   5436  H  HA   . LEU   B 1 37  ? 43.144  1.317   73.987  1.00 47.83  ?  36  LEU   A HA   1 
ATOM   5437  H  HB2  . LEU   B 1 37  ? 44.316  2.227   75.687  1.00 39.52  ?  36  LEU   A HB2  1 
ATOM   5438  H  HB3  . LEU   B 1 37  ? 45.396  2.837   74.695  1.00 39.52  ?  36  LEU   A HB3  1 
ATOM   5439  H  HG   . LEU   B 1 37  ? 43.796  4.467   74.051  1.00 41.53  ?  36  LEU   A HG   1 
ATOM   5440  H  HD11 . LEU   B 1 37  ? 41.874  4.618   75.347  1.00 52.96  ?  36  LEU   A HD11 1 
ATOM   5441  H  HD12 . LEU   B 1 37  ? 41.908  3.227   74.580  1.00 52.96  ?  36  LEU   A HD12 1 
ATOM   5442  H  HD13 . LEU   B 1 37  ? 42.293  3.295   76.120  1.00 52.96  ?  36  LEU   A HD13 1 
ATOM   5443  H  HD21 . LEU   B 1 37  ? 44.011  5.753   75.974  1.00 49.78  ?  36  LEU   A HD21 1 
ATOM   5444  H  HD22 . LEU   B 1 37  ? 44.431  4.465   76.803  1.00 49.78  ?  36  LEU   A HD22 1 
ATOM   5445  H  HD23 . LEU   B 1 37  ? 45.388  5.024   75.666  1.00 49.78  ?  36  LEU   A HD23 1 
ATOM   5446  N  N    . ASP   B 1 38  ? 42.739  2.280   71.769  1.00 40.77  ?  37  ASP   A N    1 
ATOM   5447  C  CA   . ASP   B 1 38  ? 42.460  2.874   70.458  1.00 47.51  ?  37  ASP   A CA   1 
ATOM   5448  C  C    . ASP   B 1 38  ? 43.597  2.620   69.484  1.00 35.98  ?  37  ASP   A C    1 
ATOM   5449  O  O    . ASP   B 1 38  ? 44.115  3.529   68.847  1.00 42.25  ?  37  ASP   A O    1 
ATOM   5450  C  CB   . ASP   B 1 38  ? 42.167  4.368   70.592  1.00 46.10  ?  37  ASP   A CB   1 
ATOM   5451  C  CG   . ASP   B 1 38  ? 40.911  4.648   71.443  1.00 65.44  ?  37  ASP   A CG   1 
ATOM   5452  O  OD1  . ASP   B 1 38  ? 40.979  5.572   72.302  1.00 73.83  ?  37  ASP   A OD1  1 
ATOM   5453  O  OD2  . ASP   B 1 38  ? 39.859  3.959   71.269  1.00 67.55  ?  37  ASP   A OD2  1 
ATOM   5454  H  H    . ASP   B 1 38  ? 42.068  1.848   72.089  1.00 48.92  ?  37  ASP   A H    1 
ATOM   5455  H  HA   . ASP   B 1 38  ? 41.671  2.446   70.092  1.00 57.01  ?  37  ASP   A HA   1 
ATOM   5456  H  HB2  . ASP   B 1 38  ? 42.923  4.803   71.018  1.00 55.31  ?  37  ASP   A HB2  1 
ATOM   5457  H  HB3  . ASP   B 1 38  ? 42.023  4.744   69.710  1.00 55.31  ?  37  ASP   A HB3  1 
ATOM   5458  N  N    . GLY   B 1 39  ? 44.020  1.370   69.421  1.00 34.72  ?  38  GLY   A N    1 
ATOM   5459  C  CA   . GLY   B 1 39  ? 45.122  0.931   68.574  1.00 43.18  ?  38  GLY   A CA   1 
ATOM   5460  C  C    . GLY   B 1 39  ? 46.509  0.868   69.188  1.00 49.12  ?  38  GLY   A C    1 
ATOM   5461  O  O    . GLY   B 1 39  ? 47.312  -0.018  68.863  1.00 45.44  ?  38  GLY   A O    1 
ATOM   5462  H  H    . GLY   B 1 39  ? 43.672  0.729   69.877  1.00 41.66  ?  38  GLY   A H    1 
ATOM   5463  H  HA2  . GLY   B 1 39  ? 44.915  0.039   68.254  1.00 51.82  ?  38  GLY   A HA2  1 
ATOM   5464  H  HA3  . GLY   B 1 39  ? 45.175  1.534   67.817  1.00 51.82  ?  38  GLY   A HA3  1 
ATOM   5465  N  N    . ALA   B 1 40  ? 46.799  1.794   70.101  1.00 47.26  ?  39  ALA   A N    1 
ATOM   5466  C  CA   . ALA   B 1 40  ? 48.144  1.935   70.645  1.00 40.81  ?  39  ALA   A CA   1 
ATOM   5467  C  C    . ALA   B 1 40  ? 48.487  0.858   71.666  1.00 40.21  ?  39  ALA   A C    1 
ATOM   5468  O  O    . ALA   B 1 40  ? 47.709  0.530   72.549  1.00 43.74  ?  39  ALA   A O    1 
ATOM   5469  C  CB   . ALA   B 1 40  ? 48.298  3.320   71.271  1.00 38.56  ?  39  ALA   A CB   1 
ATOM   5470  H  H    . ALA   B 1 40  ? 46.230  2.354   70.422  1.00 56.72  ?  39  ALA   A H    1 
ATOM   5471  H  HA   . ALA   B 1 40  ? 48.779  1.832   69.919  1.00 48.97  ?  39  ALA   A HA   1 
ATOM   5472  H  HB1  . ALA   B 1 40  ? 49.137  3.355   71.757  1.00 46.27  ?  39  ALA   A HB1  1 
ATOM   5473  H  HB2  . ALA   B 1 40  ? 48.296  3.987   70.567  1.00 46.27  ?  39  ALA   A HB2  1 
ATOM   5474  H  HB3  . ALA   B 1 40  ? 47.558  3.476   71.878  1.00 46.27  ?  39  ALA   A HB3  1 
ATOM   5475  N  N    . ASP   B 1 41  ? 49.687  0.333   71.558  1.00 46.71  ?  40  ASP   A N    1 
ATOM   5476  C  CA   . ASP   B 1 41  ? 50.168  -0.686  72.472  1.00 43.56  ?  40  ASP   A CA   1 
ATOM   5477  C  C    . ASP   B 1 41  ? 50.553  -0.031  73.799  1.00 52.35  ?  40  ASP   A C    1 
ATOM   5478  O  O    . ASP   B 1 41  ? 51.432  0.840   73.851  1.00 54.92  ?  40  ASP   A O    1 
ATOM   5479  C  CB   . ASP   B 1 41  ? 51.337  -1.418  71.836  1.00 46.93  ?  40  ASP   A CB   1 
ATOM   5480  C  CG   . ASP   B 1 41  ? 51.692  -2.664  72.578  1.00 52.21  ?  40  ASP   A CG   1 
ATOM   5481  O  OD1  . ASP   B 1 41  ? 52.310  -3.545  71.958  1.00 51.13  ?  40  ASP   A OD1  1 
ATOM   5482  O  OD2  . ASP   B 1 41  ? 51.355  -2.772  73.776  1.00 56.53  ?  40  ASP   A OD2  1 
ATOM   5483  H  H    . ASP   B 1 41  ? 50.257  0.553   70.952  1.00 56.05  ?  40  ASP   A H    1 
ATOM   5484  H  HA   . ASP   B 1 41  ? 49.474  -1.336  72.661  1.00 52.27  ?  40  ASP   A HA   1 
ATOM   5485  H  HB2  . ASP   B 1 41  ? 51.102  -1.663  70.927  1.00 56.32  ?  40  ASP   A HB2  1 
ATOM   5486  H  HB3  . ASP   B 1 41  ? 52.113  -0.837  71.833  1.00 56.32  ?  40  ASP   A HB3  1 
ATOM   5487  N  N    . VAL   B 1 42  ? 49.856  -0.417  74.865  1.00 50.44  ?  41  VAL   A N    1 
ATOM   5488  C  CA   . VAL   B 1 42  ? 50.102  0.138   76.184  1.00 52.22  ?  41  VAL   A CA   1 
ATOM   5489  C  C    . VAL   B 1 42  ? 50.590  -0.905  77.171  1.00 40.84  ?  41  VAL   A C    1 
ATOM   5490  O  O    . VAL   B 1 42  ? 50.501  -0.679  78.389  1.00 41.20  ?  41  VAL   A O    1 
ATOM   5491  C  CB   . VAL   B 1 42  ? 48.845  0.825   76.748  1.00 49.56  ?  41  VAL   A CB   1 
ATOM   5492  C  CG1  . VAL   B 1 42  ? 48.402  1.927   75.834  1.00 45.41  ?  41  VAL   A CG1  1 
ATOM   5493  C  CG2  . VAL   B 1 42  ? 47.735  -0.203  76.972  1.00 46.32  ?  41  VAL   A CG2  1 
ATOM   5494  H  H    . VAL   B 1 42  ? 49.230  -1.006  74.844  1.00 60.52  ?  41  VAL   A H    1 
ATOM   5495  H  HA   . VAL   B 1 42  ? 50.802  0.802   76.085  1.00 62.66  ?  41  VAL   A HA   1 
ATOM   5496  H  HB   . VAL   B 1 42  ? 49.051  1.224   77.607  1.00 59.48  ?  41  VAL   A HB   1 
ATOM   5497  H  HG11 . VAL   B 1 42  ? 47.917  2.590   76.350  1.00 54.49  ?  41  VAL   A HG11 1 
ATOM   5498  H  HG12 . VAL   B 1 42  ? 49.183  2.333   75.426  1.00 54.49  ?  41  VAL   A HG12 1 
ATOM   5499  H  HG13 . VAL   B 1 42  ? 47.826  1.556   75.147  1.00 54.49  ?  41  VAL   A HG13 1 
ATOM   5500  H  HG21 . VAL   B 1 42  ? 46.951  0.250   77.319  1.00 55.58  ?  41  VAL   A HG21 1 
ATOM   5501  H  HG22 . VAL   B 1 42  ? 47.524  -0.629  76.127  1.00 55.58  ?  41  VAL   A HG22 1 
ATOM   5502  H  HG23 . VAL   B 1 42  ? 48.043  -0.866  77.609  1.00 55.58  ?  41  VAL   A HG23 1 
ATOM   5503  N  N    . THR   B 1 43  ? 51.012  -2.067  76.677  1.00 39.96  ?  42  THR   A N    1 
ATOM   5504  C  CA   . THR   B 1 43  ? 51.446  -3.142  77.556  1.00 50.58  ?  42  THR   A CA   1 
ATOM   5505  C  C    . THR   B 1 43  ? 52.552  -2.696  78.506  1.00 53.66  ?  42  THR   A C    1 
ATOM   5506  O  O    . THR   B 1 43  ? 52.629  -3.184  79.648  1.00 46.49  ?  42  THR   A O    1 
ATOM   5507  C  CB   . THR   B 1 43  ? 51.939  -4.317  76.715  1.00 52.34  ?  42  THR   A CB   1 
ATOM   5508  O  OG1  . THR   B 1 43  ? 51.011  -4.558  75.654  1.00 58.83  ?  42  THR   A OG1  1 
ATOM   5509  C  CG2  . THR   B 1 43  ? 52.076  -5.557  77.561  1.00 56.70  ?  42  THR   A CG2  1 
ATOM   5510  H  H    . THR   B 1 43  ? 51.057  -2.255  75.839  1.00 47.95  ?  42  THR   A H    1 
ATOM   5511  H  HA   . THR   B 1 43  ? 50.689  -3.427  78.091  1.00 60.70  ?  42  THR   A HA   1 
ATOM   5512  H  HB   . THR   B 1 43  ? 52.811  -4.112  76.343  1.00 62.81  ?  42  THR   A HB   1 
ATOM   5513  H  HG1  . THR   B 1 43  ? 51.038  -3.927  75.100  1.00 70.59  ?  42  THR   A HG1  1 
ATOM   5514  H  HG21 . THR   B 1 43  ? 52.353  -6.306  77.010  1.00 68.04  ?  42  THR   A HG21 1 
ATOM   5515  H  HG22 . THR   B 1 43  ? 52.739  -5.414  78.254  1.00 68.04  ?  42  THR   A HG22 1 
ATOM   5516  H  HG23 . THR   B 1 43  ? 51.226  -5.770  77.977  1.00 68.04  ?  42  THR   A HG23 1 
ATOM   5517  N  N    . LYS   B 1 44  ? 53.411  -1.782  78.055  1.00 50.36  ?  43  LYS   A N    1 
ATOM   5518  C  CA   . LYS   B 1 44  ? 54.547  -1.321  78.835  1.00 54.03  ?  43  LYS   A CA   1 
ATOM   5519  C  C    . LYS   B 1 44  ? 54.346  0.063   79.430  1.00 54.78  ?  43  LYS   A C    1 
ATOM   5520  O  O    . LYS   B 1 44  ? 55.320  0.645   79.900  1.00 54.01  ?  43  LYS   A O    1 
ATOM   5521  C  CB   . LYS   B 1 44  ? 55.806  -1.339  77.960  1.00 51.45  ?  43  LYS   A CB   1 
ATOM   5522  C  CG   . LYS   B 1 44  ? 56.142  -2.746  77.371  1.00 54.46  ?  43  LYS   A CG   1 
ATOM   5523  C  CD   . LYS   B 1 44  ? 57.200  -2.717  76.242  1.00 65.31  ?  43  LYS   A CD   1 
ATOM   5524  C  CE   . LYS   B 1 44  ? 58.665  -2.776  76.770  1.00 70.96  ?  43  LYS   A CE   1 
ATOM   5525  N  NZ   . LYS   B 1 44  ? 59.561  -1.708  76.198  1.00 59.14  ?  43  LYS   A NZ   1 
ATOM   5526  H  H    . LYS   B 1 44  ? 53.351  -1.410  77.282  1.00 60.43  ?  43  LYS   A H    1 
ATOM   5527  H  HA   . LYS   B 1 44  ? 54.677  -1.932  79.577  1.00 64.84  ?  43  LYS   A HA   1 
ATOM   5528  H  HB2  . LYS   B 1 44  ? 55.679  -0.729  77.216  1.00 61.74  ?  43  LYS   A HB2  1 
ATOM   5529  H  HB3  . LYS   B 1 44  ? 56.563  -1.054  78.496  1.00 61.74  ?  43  LYS   A HB3  1 
ATOM   5530  H  HG2  . LYS   B 1 44  ? 56.486  -3.308  78.083  1.00 65.35  ?  43  LYS   A HG2  1 
ATOM   5531  H  HG3  . LYS   B 1 44  ? 55.332  -3.133  77.005  1.00 65.35  ?  43  LYS   A HG3  1 
ATOM   5532  H  HD2  . LYS   B 1 44  ? 57.062  -3.481  75.662  1.00 78.37  ?  43  LYS   A HD2  1 
ATOM   5533  H  HD3  . LYS   B 1 44  ? 57.099  -1.894  75.738  1.00 78.37  ?  43  LYS   A HD3  1 
ATOM   5534  H  HE2  . LYS   B 1 44  ? 58.655  -2.667  77.734  1.00 85.15  ?  43  LYS   A HE2  1 
ATOM   5535  H  HE3  . LYS   B 1 44  ? 59.046  -3.637  76.537  1.00 85.15  ?  43  LYS   A HE3  1 
ATOM   5536  H  HZ1  . LYS   B 1 44  ? 60.381  -1.786  76.534  1.00 70.96  ?  43  LYS   A HZ1  1 
ATOM   5537  H  HZ2  . LYS   B 1 44  ? 59.602  -1.787  75.313  1.00 70.96  ?  43  LYS   A HZ2  1 
ATOM   5538  H  HZ3  . LYS   B 1 44  ? 59.242  -0.902  76.401  1.00 70.96  ?  43  LYS   A HZ3  1 
ATOM   5539  N  N    . ILE   B 1 45  ? 53.109  0.581   79.468  1.00 50.57  ?  44  ILE   A N    1 
ATOM   5540  C  CA   . ILE   B 1 45  ? 52.809  1.907   80.004  1.00 46.50  ?  44  ILE   A CA   1 
ATOM   5541  C  C    . ILE   B 1 45  ? 52.115  1.766   81.352  1.00 58.34  ?  44  ILE   A C    1 
ATOM   5542  O  O    . ILE   B 1 45  ? 51.423  0.777   81.627  1.00 61.23  ?  44  ILE   A O    1 
ATOM   5543  C  CB   . ILE   B 1 45  ? 51.942  2.724   79.023  1.00 57.83  ?  44  ILE   A CB   1 
ATOM   5544  C  CG1  . ILE   B 1 45  ? 52.765  3.056   77.766  1.00 57.63  ?  44  ILE   A CG1  1 
ATOM   5545  C  CG2  . ILE   B 1 45  ? 51.398  3.966   79.692  1.00 61.78  ?  44  ILE   A CG2  1 
ATOM   5546  C  CD1  . ILE   B 1 45  ? 53.348  4.435   77.752  1.00 75.54  ?  44  ILE   A CD1  1 
ATOM   5547  H  H    . ILE   B 1 45  ? 52.412  0.167   79.181  1.00 60.68  ?  44  ILE   A H    1 
ATOM   5548  H  HA   . ILE   B 1 45  ? 53.641  2.381   80.152  1.00 55.80  ?  44  ILE   A HA   1 
ATOM   5549  H  HB   . ILE   B 1 45  ? 51.177  2.193   78.753  1.00 69.40  ?  44  ILE   A HB   1 
ATOM   5550  H  HG12 . ILE   B 1 45  ? 53.499  2.426   77.702  1.00 69.16  ?  44  ILE   A HG12 1 
ATOM   5551  H  HG13 . ILE   B 1 45  ? 52.189  2.974   76.990  1.00 69.16  ?  44  ILE   A HG13 1 
ATOM   5552  H  HG21 . ILE   B 1 45  ? 50.898  4.482   79.040  1.00 74.13  ?  44  ILE   A HG21 1 
ATOM   5553  H  HG22 . ILE   B 1 45  ? 50.817  3.703   80.422  1.00 74.13  ?  44  ILE   A HG22 1 
ATOM   5554  H  HG23 . ILE   B 1 45  ? 52.139  4.492   80.032  1.00 74.13  ?  44  ILE   A HG23 1 
ATOM   5555  H  HD11 . ILE   B 1 45  ? 53.869  4.549   76.941  1.00 90.65  ?  44  ILE   A HD11 1 
ATOM   5556  H  HD12 . ILE   B 1 45  ? 52.628  5.083   77.775  1.00 90.65  ?  44  ILE   A HD12 1 
ATOM   5557  H  HD13 . ILE   B 1 45  ? 53.918  4.545   78.529  1.00 90.65  ?  44  ILE   A HD13 1 
ATOM   5558  N  N    . LYS   B 1 46  ? 52.304  2.758   82.193  1.00 54.41  ?  45  LYS   A N    1 
ATOM   5559  C  CA   . LYS   B 1 46  ? 51.592  2.749   83.457  1.00 58.15  ?  45  LYS   A CA   1 
ATOM   5560  C  C    . LYS   B 1 46  ? 50.306  3.561   83.343  1.00 51.27  ?  45  LYS   A C    1 
ATOM   5561  O  O    . LYS   B 1 46  ? 50.231  4.505   82.553  1.00 50.93  ?  45  LYS   A O    1 
ATOM   5562  C  CB   . LYS   B 1 46  ? 52.471  3.320   84.581  1.00 60.93  ?  45  LYS   A CB   1 
ATOM   5563  C  CG   . LYS   B 1 46  ? 53.293  2.268   85.354  1.00 65.11  ?  45  LYS   A CG   1 
ATOM   5564  C  CD   . LYS   B 1 46  ? 54.132  2.912   86.485  1.00 79.90  ?  45  LYS   A CD   1 
ATOM   5565  C  CE   . LYS   B 1 46  ? 55.158  1.946   87.104  1.00 73.38  ?  45  LYS   A CE   1 
ATOM   5566  N  NZ   . LYS   B 1 46  ? 54.471  0.744   87.684  1.00 69.43  ?  45  LYS   A NZ   1 
ATOM   5567  H  H    . LYS   B 1 46  ? 52.824  3.430   82.063  1.00 65.29  ?  45  LYS   A H    1 
ATOM   5568  H  HA   . LYS   B 1 46  ? 51.359  1.839   83.702  1.00 69.78  ?  45  LYS   A HA   1 
ATOM   5569  H  HB2  . LYS   B 1 46  ? 53.097  3.951   84.192  1.00 73.12  ?  45  LYS   A HB2  1 
ATOM   5570  H  HB3  . LYS   B 1 46  ? 51.899  3.772   85.221  1.00 73.12  ?  45  LYS   A HB3  1 
ATOM   5571  H  HG2  . LYS   B 1 46  ? 52.690  1.621   85.753  1.00 78.13  ?  45  LYS   A HG2  1 
ATOM   5572  H  HG3  . LYS   B 1 46  ? 53.900  1.823   84.742  1.00 78.13  ?  45  LYS   A HG3  1 
ATOM   5573  H  HD2  . LYS   B 1 46  ? 54.617  3.670   86.125  1.00 95.89  ?  45  LYS   A HD2  1 
ATOM   5574  H  HD3  . LYS   B 1 46  ? 53.535  3.205   87.192  1.00 95.89  ?  45  LYS   A HD3  1 
ATOM   5575  H  HE2  . LYS   B 1 46  ? 55.776  1.647   86.420  1.00 88.06  ?  45  LYS   A HE2  1 
ATOM   5576  H  HE3  . LYS   B 1 46  ? 55.641  2.397   87.814  1.00 88.06  ?  45  LYS   A HE3  1 
ATOM   5577  H  HZ1  . LYS   B 1 46  ? 55.072  0.192   88.039  1.00 83.32  ?  45  LYS   A HZ1  1 
ATOM   5578  H  HZ2  . LYS   B 1 46  ? 53.900  0.997   88.318  1.00 83.32  ?  45  LYS   A HZ2  1 
ATOM   5579  H  HZ3  . LYS   B 1 46  ? 54.023  0.313   87.047  1.00 83.32  ?  45  LYS   A HZ3  1 
ATOM   5580  N  N    . PRO   B 1 47  ? 49.274  3.209   84.105  1.00 45.34  ?  46  PRO   A N    1 
ATOM   5581  C  CA   . PRO   B 1 47  ? 48.040  4.004   84.079  1.00 56.59  ?  46  PRO   A CA   1 
ATOM   5582  C  C    . PRO   B 1 47  ? 48.263  5.499   84.292  1.00 59.85  ?  46  PRO   A C    1 
ATOM   5583  O  O    . PRO   B 1 47  ? 49.120  5.917   85.070  1.00 60.38  ?  46  PRO   A O    1 
ATOM   5584  C  CB   . PRO   B 1 47  ? 47.216  3.395   85.215  1.00 48.95  ?  46  PRO   A CB   1 
ATOM   5585  C  CG   . PRO   B 1 47  ? 47.604  1.915   85.171  1.00 51.83  ?  46  PRO   A CG   1 
ATOM   5586  C  CD   . PRO   B 1 47  ? 49.097  1.930   84.827  1.00 49.02  ?  46  PRO   A CD   1 
ATOM   5587  H  HA   . PRO   B 1 47  ? 47.600  3.883   83.223  1.00 67.91  ?  46  PRO   A HA   1 
ATOM   5588  H  HB2  . PRO   B 1 47  ? 47.459  3.799   86.063  1.00 58.74  ?  46  PRO   A HB2  1 
ATOM   5589  H  HB3  . PRO   B 1 47  ? 46.268  3.517   85.049  1.00 58.74  ?  46  PRO   A HB3  1 
ATOM   5590  H  HG2  . PRO   B 1 47  ? 47.448  1.503   86.035  1.00 62.19  ?  46  PRO   A HG2  1 
ATOM   5591  H  HG3  . PRO   B 1 47  ? 47.092  1.456   84.487  1.00 62.19  ?  46  PRO   A HG3  1 
ATOM   5592  H  HD2  . PRO   B 1 47  ? 49.636  1.912   85.633  1.00 58.83  ?  46  PRO   A HD2  1 
ATOM   5593  H  HD3  . PRO   B 1 47  ? 49.327  1.179   84.258  1.00 58.83  ?  46  PRO   A HD3  1 
ATOM   5594  N  N    . HIS   B 1 48  ? 47.481  6.296   83.563  1.00 52.75  ?  47  HIS   A N    1 
ATOM   5595  C  CA   . HIS   B 1 48  ? 47.391  7.744   83.674  1.00 48.39  ?  47  HIS   A CA   1 
ATOM   5596  C  C    . HIS   B 1 48  ? 46.046  8.106   84.286  1.00 49.88  ?  47  HIS   A C    1 
ATOM   5597  O  O    . HIS   B 1 48  ? 45.069  7.360   84.173  1.00 42.09  ?  47  HIS   A O    1 
ATOM   5598  C  CB   . HIS   B 1 48  ? 47.521  8.403   82.295  1.00 47.23  ?  47  HIS   A CB   1 
ATOM   5599  C  CG   . HIS   B 1 48  ? 47.696  9.888   82.338  1.00 54.22  ?  47  HIS   A CG   1 
ATOM   5600  N  ND1  . HIS   B 1 48  ? 46.692  10.769  81.992  1.00 54.38  ?  47  HIS   A ND1  1 
ATOM   5601  C  CD2  . HIS   B 1 48  ? 48.782  10.649  82.628  1.00 68.34  ?  47  HIS   A CD2  1 
ATOM   5602  C  CE1  . HIS   B 1 48  ? 47.139  12.008  82.105  1.00 58.90  ?  47  HIS   A CE1  1 
ATOM   5603  N  NE2  . HIS   B 1 48  ? 48.407  11.963  82.485  1.00 65.02  ?  47  HIS   A NE2  1 
ATOM   5604  H  H    . HIS   B 1 48  ? 46.956  5.995   82.953  1.00 63.30  ?  47  HIS   A H    1 
ATOM   5605  H  HA   . HIS   B 1 48  ? 48.103  8.083   84.239  1.00 58.06  ?  47  HIS   A HA   1 
ATOM   5606  H  HB2  . HIS   B 1 48  ? 48.295  8.029   81.845  1.00 56.68  ?  47  HIS   A HB2  1 
ATOM   5607  H  HB3  . HIS   B 1 48  ? 46.718  8.216   81.785  1.00 56.68  ?  47  HIS   A HB3  1 
ATOM   5608  H  HD1  . HIS   B 1 48  ? 45.899  10.547  81.742  1.00 65.26  ?  47  HIS   A HD1  1 
ATOM   5609  H  HD2  . HIS   B 1 48  ? 49.623  10.339  82.877  1.00 82.00  ?  47  HIS   A HD2  1 
ATOM   5610  H  HE1  . HIS   B 1 48  ? 46.647  12.781  81.946  1.00 70.67  ?  47  HIS   A HE1  1 
ATOM   5611  N  N    . ASN   B 1 49  ? 45.995  9.271   84.937  1.00 57.76  ?  48  ASN   A N    1 
ATOM   5612  C  CA   . ASN   B 1 49  ? 44.722  9.721   85.499  1.00 47.42  ?  48  ASN   A CA   1 
ATOM   5613  C  C    . ASN   B 1 49  ? 43.645  9.828   84.424  1.00 44.15  ?  48  ASN   A C    1 
ATOM   5614  O  O    . ASN   B 1 49  ? 42.469  9.569   84.689  1.00 49.37  ?  48  ASN   A O    1 
ATOM   5615  C  CB   . ASN   B 1 49  ? 44.897  11.080  86.190  1.00 53.39  ?  48  ASN   A CB   1 
ATOM   5616  C  CG   . ASN   B 1 49  ? 45.445  10.961  87.610  1.00 60.24  ?  48  ASN   A CG   1 
ATOM   5617  O  OD1  . ASN   B 1 49  ? 45.867  9.891   88.026  1.00 50.48  ?  48  ASN   A OD1  1 
ATOM   5618  N  ND2  . ASN   B 1 49  ? 45.457  12.071  88.342  1.00 72.46  ?  48  ASN   A ND2  1 
ATOM   5619  H  H    . ASN   B 1 49  ? 46.660  9.801   85.063  1.00 69.31  ?  48  ASN   A H    1 
ATOM   5620  H  HA   . ASN   B 1 49  ? 44.435  9.076   86.163  1.00 56.90  ?  48  ASN   A HA   1 
ATOM   5621  H  HB2  . ASN   B 1 49  ? 45.518  11.618  85.675  1.00 64.07  ?  48  ASN   A HB2  1 
ATOM   5622  H  HB3  . ASN   B 1 49  ? 44.035  11.522  86.239  1.00 64.07  ?  48  ASN   A HB3  1 
ATOM   5623  H  HD21 . ASN   B 1 49  ? 45.165  12.809  88.010  1.00 86.95  ?  48  ASN   A HD21 1 
ATOM   5624  H  HD22 . ASN   B 1 49  ? 45.757  12.051  89.148  1.00 86.95  ?  48  ASN   A HD22 1 
ATOM   5625  N  N    . SER   B 1 50  ? 44.022  10.194  83.205  1.00 44.83  ?  49  SER   A N    1 
ATOM   5626  C  CA   . SER   B 1 50  ? 43.030  10.423  82.163  1.00 48.66  ?  49  SER   A CA   1 
ATOM   5627  C  C    . SER   B 1 50  ? 42.394  9.144   81.633  1.00 43.04  ?  49  SER   A C    1 
ATOM   5628  O  O    . SER   B 1 50  ? 41.466  9.229   80.826  1.00 43.16  ?  49  SER   A O    1 
ATOM   5629  C  CB   . SER   B 1 50  ? 43.702  11.165  81.016  1.00 45.24  ?  49  SER   A CB   1 
ATOM   5630  O  OG   . SER   B 1 50  ? 44.721  10.360  80.423  1.00 45.53  ?  49  SER   A OG   1 
ATOM   5631  H  HA   . SER   B 1 50  ? 42.312  10.964  82.526  1.00 58.39  ?  49  SER   A HA   1 
ATOM   5632  H  HB2  . SER   B 1 50  ? 43.036  11.378  80.344  1.00 54.29  ?  49  SER   A HB2  1 
ATOM   5633  H  HB3  . SER   B 1 50  ? 44.101  11.980  81.357  1.00 54.29  ?  49  SER   A HB3  1 
ATOM   5634  N  N    . HIS   B 1 51  ? 42.868  7.974   82.044  1.00 46.82  ?  50  HIS   A N    1 
ATOM   5635  C  CA   . HIS   B 1 51  ? 42.377  6.730   81.491  1.00 39.94  ?  50  HIS   A CA   1 
ATOM   5636  C  C    . HIS   B 1 51  ? 41.142  6.216   82.197  1.00 47.09  ?  50  HIS   A C    1 
ATOM   5637  O  O    . HIS   B 1 51  ? 40.502  5.299   81.675  1.00 44.35  ?  50  HIS   A O    1 
ATOM   5638  C  CB   . HIS   B 1 51  ? 43.444  5.636   81.546  1.00 42.55  ?  50  HIS   A CB   1 
ATOM   5639  C  CG   . HIS   B 1 51  ? 44.660  5.934   80.726  1.00 43.94  ?  50  HIS   A CG   1 
ATOM   5640  N  ND1  . HIS   B 1 51  ? 45.819  5.195   80.818  1.00 48.93  ?  50  HIS   A ND1  1 
ATOM   5641  C  CD2  . HIS   B 1 51  ? 44.911  6.912   79.825  1.00 47.72  ?  50  HIS   A CD2  1 
ATOM   5642  C  CE1  . HIS   B 1 51  ? 46.735  5.696   80.004  1.00 48.54  ?  50  HIS   A CE1  1 
ATOM   5643  N  NE2  . HIS   B 1 51  ? 46.210  6.745   79.395  1.00 51.64  ?  50  HIS   A NE2  1 
ATOM   5644  H  H    . HIS   B 1 51  ? 43.476  7.879   82.645  1.00 56.18  ?  50  HIS   A H    1 
ATOM   5645  H  HA   . HIS   B 1 51  ? 42.165  6.893   80.559  1.00 47.93  ?  50  HIS   A HA   1 
ATOM   5646  H  HB2  . HIS   B 1 51  ? 43.729  5.525   82.467  1.00 51.06  ?  50  HIS   A HB2  1 
ATOM   5647  H  HB3  . HIS   B 1 51  ? 43.060  4.809   81.215  1.00 51.06  ?  50  HIS   A HB3  1 
ATOM   5648  H  HD2  . HIS   B 1 51  ? 44.318  7.572   79.547  1.00 57.26  ?  50  HIS   A HD2  1 
ATOM   5649  H  HE1  . HIS   B 1 51  ? 47.597  5.368   79.883  1.00 58.25  ?  50  HIS   A HE1  1 
ATOM   5650  H  HE2  . HIS   B 1 51  ? 46.614  7.243   78.822  1.00 61.96  ?  50  HIS   A HE2  1 
ATOM   5651  N  N    . GLU   B 1 52  ? 40.805  6.750   83.375  1.00 45.14  ?  51  GLU   A N    1 
ATOM   5652  C  CA   . GLU   B 1 52  ? 39.602  6.295   84.056  1.00 44.93  ?  51  GLU   A CA   1 
ATOM   5653  C  C    . GLU   B 1 52  ? 38.426  6.414   83.084  1.00 42.63  ?  51  GLU   A C    1 
ATOM   5654  O  O    . GLU   B 1 52  ? 38.285  7.402   82.361  1.00 46.85  ?  51  GLU   A O    1 
ATOM   5655  C  CB   . GLU   B 1 52  ? 39.338  7.089   85.355  1.00 49.67  ?  51  GLU   A CB   1 
ATOM   5656  C  CG   . GLU   B 1 52  ? 37.911  6.866   85.911  1.00 59.17  ?  51  GLU   A CG   1 
ATOM   5657  C  CD   . GLU   B 1 52  ? 37.841  6.504   87.406  1.00 64.30  ?  51  GLU   A CD   1 
ATOM   5658  O  OE1  . GLU   B 1 52  ? 38.875  6.228   88.026  1.00 64.86  ?  51  GLU   A OE1  1 
ATOM   5659  O  OE2  . GLU   B 1 52  ? 36.724  6.502   87.966  1.00 94.27  ?  51  GLU   A OE2  1 
ATOM   5660  H  H    . GLU   B 1 52  ? 41.249  7.361   83.787  1.00 54.16  ?  51  GLU   A H    1 
ATOM   5661  H  HA   . GLU   B 1 52  ? 39.705  5.371   84.334  1.00 53.91  ?  51  GLU   A HA   1 
ATOM   5662  H  HB2  . GLU   B 1 52  ? 39.972  6.806   86.033  1.00 59.61  ?  51  GLU   A HB2  1 
ATOM   5663  H  HB3  . GLU   B 1 52  ? 39.446  8.036   85.174  1.00 59.61  ?  51  GLU   A HB3  1 
ATOM   5664  H  HG2  . GLU   B 1 52  ? 37.402  7.683   85.787  1.00 71.01  ?  51  GLU   A HG2  1 
ATOM   5665  H  HG3  . GLU   B 1 52  ? 37.499  6.140   85.418  1.00 71.01  ?  51  GLU   A HG3  1 
ATOM   5666  N  N    . GLY   B 1 53  ? 37.585  5.391   83.056  1.00 40.14  ?  52  GLY   A N    1 
ATOM   5667  C  CA   . GLY   B 1 53  ? 36.460  5.340   82.163  1.00 38.97  ?  52  GLY   A CA   1 
ATOM   5668  C  C    . GLY   B 1 53  ? 36.770  4.791   80.777  1.00 45.29  ?  52  GLY   A C    1 
ATOM   5669  O  O    . GLY   B 1 53  ? 35.870  4.216   80.147  1.00 43.79  ?  52  GLY   A O    1 
ATOM   5670  H  H    . GLY   B 1 53  ? 37.655  4.699   83.563  1.00 48.17  ?  52  GLY   A H    1 
ATOM   5671  H  HA2  . GLY   B 1 53  ? 35.775  4.778   82.557  1.00 46.76  ?  52  GLY   A HA2  1 
ATOM   5672  H  HA3  . GLY   B 1 53  ? 36.109  6.237   82.054  1.00 46.76  ?  52  GLY   A HA3  1 
ATOM   5673  N  N    . LYS   B 1 54  ? 38.001  4.983   80.269  1.00 35.54  ?  53  LYS   A N    1 
ATOM   5674  C  CA   . LYS   B 1 54  ? 38.327  4.573   78.897  1.00 35.02  ?  53  LYS   A CA   1 
ATOM   5675  C  C    . LYS   B 1 54  ? 38.199  3.056   78.762  1.00 36.78  ?  53  LYS   A C    1 
ATOM   5676  O  O    . LYS   B 1 54  ? 38.132  2.312   79.754  1.00 32.63  ?  53  LYS   A O    1 
ATOM   5677  C  CB   . LYS   B 1 54  ? 39.744  4.970   78.480  1.00 30.95  ?  53  LYS   A CB   1 
ATOM   5678  C  CG   . LYS   B 1 54  ? 40.063  6.450   78.594  1.00 39.88  ?  53  LYS   A CG   1 
ATOM   5679  C  CD   . LYS   B 1 54  ? 39.804  7.213   77.323  1.00 44.60  ?  53  LYS   A CD   1 
ATOM   5680  C  CE   . LYS   B 1 54  ? 40.489  8.579   77.323  1.00 40.27  ?  53  LYS   A CE   1 
ATOM   5681  N  NZ   . LYS   B 1 54  ? 41.586  8.665   76.264  1.00 47.10  ?  53  LYS   A NZ   1 
ATOM   5682  H  H    . LYS   B 1 54  ? 38.655  5.343   80.696  1.00 42.65  ?  53  LYS   A H    1 
ATOM   5683  H  HA   . LYS   B 1 54  ? 37.706  5.027   78.306  1.00 42.03  ?  53  LYS   A HA   1 
ATOM   5684  H  HB2  . LYS   B 1 54  ? 40.374  4.493   79.044  1.00 37.14  ?  53  LYS   A HB2  1 
ATOM   5685  H  HB3  . LYS   B 1 54  ? 39.872  4.716   77.553  1.00 37.14  ?  53  LYS   A HB3  1 
ATOM   5686  H  HG2  . LYS   B 1 54  ? 39.512  6.838   79.291  1.00 47.85  ?  53  LYS   A HG2  1 
ATOM   5687  H  HG3  . LYS   B 1 54  ? 41.002  6.553   78.817  1.00 47.85  ?  53  LYS   A HG3  1 
ATOM   5688  H  HD2  . LYS   B 1 54  ? 40.145  6.705   76.570  1.00 53.52  ?  53  LYS   A HD2  1 
ATOM   5689  H  HD3  . LYS   B 1 54  ? 38.850  7.354   77.224  1.00 53.52  ?  53  LYS   A HD3  1 
ATOM   5690  H  HE2  . LYS   B 1 54  ? 39.831  9.266   77.136  1.00 48.32  ?  53  LYS   A HE2  1 
ATOM   5691  H  HE3  . LYS   B 1 54  ? 40.893  8.734   78.191  1.00 48.32  ?  53  LYS   A HE3  1 
ATOM   5692  H  HZ1  . LYS   B 1 54  ? 42.015  9.442   76.332  1.00 56.51  ?  53  LYS   A HZ1  1 
ATOM   5693  H  HZ2  . LYS   B 1 54  ? 42.169  8.002   76.375  1.00 56.51  ?  53  LYS   A HZ2  1 
ATOM   5694  H  HZ3  . LYS   B 1 54  ? 41.229  8.602   75.451  1.00 56.51  ?  53  LYS   A HZ3  1 
ATOM   5695  N  N    . THR   B 1 55  ? 38.175  2.603   77.508  1.00 36.61  ?  54  THR   A N    1 
ATOM   5696  C  CA   . THR   B 1 55  ? 38.068  1.195   77.149  1.00 38.41  ?  54  THR   A CA   1 
ATOM   5697  C  C    . THR   B 1 55  ? 39.363  0.706   76.520  1.00 37.49  ?  54  THR   A C    1 
ATOM   5698  O  O    . THR   B 1 55  ? 39.918  1.364   75.646  1.00 36.52  ?  54  THR   A O    1 
ATOM   5699  C  CB   . THR   B 1 55  ? 36.896  0.975   76.171  1.00 34.83  ?  54  THR   A CB   1 
ATOM   5700  O  OG1  . THR   B 1 55  ? 35.665  1.229   76.865  1.00 38.37  ?  54  THR   A OG1  1 
ATOM   5701  C  CG2  . THR   B 1 55  ? 36.888  -0.452  75.650  1.00 35.74  ?  54  THR   A CG2  1 
ATOM   5702  H  H    . THR   B 1 55  ? 38.222  3.118   76.821  1.00 43.93  ?  54  THR   A H    1 
ATOM   5703  H  HA   . THR   B 1 55  ? 37.913  0.669   77.950  1.00 46.09  ?  54  THR   A HA   1 
ATOM   5704  H  HB   . THR   B 1 55  ? 36.984  1.572   75.412  1.00 41.79  ?  54  THR   A HB   1 
ATOM   5705  H  HG1  . THR   B 1 55  ? 35.013  1.007   76.384  1.00 46.04  ?  54  THR   A HG1  1 
ATOM   5706  H  HG21 . THR   B 1 55  ? 36.055  -0.632  75.187  1.00 42.89  ?  54  THR   A HG21 1 
ATOM   5707  H  HG22 . THR   B 1 55  ? 37.626  -0.585  75.035  1.00 42.89  ?  54  THR   A HG22 1 
ATOM   5708  H  HG23 . THR   B 1 55  ? 36.978  -1.075  76.388  1.00 42.89  ?  54  THR   A HG23 1 
ATOM   5709  N  N    . PHE   B 1 56  ? 39.786  -0.487  76.919  1.00 36.14  ?  55  PHE   A N    1 
ATOM   5710  C  CA   . PHE   B 1 56  ? 41.026  -1.092  76.478  1.00 29.59  ?  55  PHE   A CA   1 
ATOM   5711  C  C    . PHE   B 1 56  ? 40.781  -2.469  75.880  1.00 35.59  ?  55  PHE   A C    1 
ATOM   5712  O  O    . PHE   B 1 56  ? 40.148  -3.309  76.514  1.00 34.33  ?  55  PHE   A O    1 
ATOM   5713  C  CB   . PHE   B 1 56  ? 41.992  -1.260  77.678  1.00 43.14  ?  55  PHE   A CB   1 
ATOM   5714  C  CG   . PHE   B 1 56  ? 42.493  0.038   78.245  1.00 41.30  ?  55  PHE   A CG   1 
ATOM   5715  C  CD1  . PHE   B 1 56  ? 41.711  0.794   79.096  1.00 35.02  ?  55  PHE   A CD1  1 
ATOM   5716  C  CD2  . PHE   B 1 56  ? 43.723  0.513   77.888  1.00 32.53  ?  55  PHE   A CD2  1 
ATOM   5717  C  CE1  . PHE   B 1 56  ? 42.177  1.983   79.605  1.00 40.21  ?  55  PHE   A CE1  1 
ATOM   5718  C  CE2  . PHE   B 1 56  ? 44.180  1.717   78.378  1.00 39.00  ?  55  PHE   A CE2  1 
ATOM   5719  C  CZ   . PHE   B 1 56  ? 43.411  2.448   79.238  1.00 36.61  ?  55  PHE   A CZ   1 
ATOM   5720  H  H    . PHE   B 1 56  ? 39.350  -0.983  77.469  1.00 43.37  ?  55  PHE   A H    1 
ATOM   5721  H  HA   . PHE   B 1 56  ? 41.413  -0.525  75.792  1.00 35.51  ?  55  PHE   A HA   1 
ATOM   5722  H  HB2  . PHE   B 1 56  ? 41.527  -1.732  78.387  1.00 51.76  ?  55  PHE   A HB2  1 
ATOM   5723  H  HB3  . PHE   B 1 56  ? 42.762  -1.773  77.388  1.00 51.76  ?  55  PHE   A HB3  1 
ATOM   5724  H  HD1  . PHE   B 1 56  ? 40.860  0.497   79.327  1.00 42.02  ?  55  PHE   A HD1  1 
ATOM   5725  H  HD2  . PHE   B 1 56  ? 44.258  0.020   77.308  1.00 39.03  ?  55  PHE   A HD2  1 
ATOM   5726  H  HE1  . PHE   B 1 56  ? 41.654  2.471   80.200  1.00 48.25  ?  55  PHE   A HE1  1 
ATOM   5727  H  HE2  . PHE   B 1 56  ? 45.016  2.033   78.122  1.00 46.80  ?  55  PHE   A HE2  1 
ATOM   5728  H  HZ   . PHE   B 1 56  ? 43.725  3.257   79.571  1.00 43.93  ?  55  PHE   A HZ   1 
ATOM   5729  N  N    . TYR   B 1 57  ? 41.349  -2.739  74.704  1.00 44.58  ?  56  TYR   A N    1 
ATOM   5730  C  CA   . TYR   B 1 57  ? 41.320  -4.098  74.159  1.00 39.31  ?  56  TYR   A CA   1 
ATOM   5731  C  C    . TYR   B 1 57  ? 42.387  -4.917  74.855  1.00 35.07  ?  56  TYR   A C    1 
ATOM   5732  O  O    . TYR   B 1 57  ? 43.457  -4.396  75.115  1.00 39.34  ?  56  TYR   A O    1 
ATOM   5733  C  CB   . TYR   B 1 57  ? 41.601  -4.111  72.656  1.00 36.84  ?  56  TYR   A CB   1 
ATOM   5734  C  CG   . TYR   B 1 57  ? 40.436  -3.707  71.792  1.00 34.79  ?  56  TYR   A CG   1 
ATOM   5735  C  CD1  . TYR   B 1 57  ? 39.736  -4.644  71.065  1.00 38.00  ?  56  TYR   A CD1  1 
ATOM   5736  C  CD2  . TYR   B 1 57  ? 40.056  -2.386  71.694  1.00 34.73  ?  56  TYR   A CD2  1 
ATOM   5737  C  CE1  . TYR   B 1 57  ? 38.692  -4.284  70.275  1.00 45.38  ?  56  TYR   A CE1  1 
ATOM   5738  C  CE2  . TYR   B 1 57  ? 39.016  -2.013  70.919  1.00 39.07  ?  56  TYR   A CE2  1 
ATOM   5739  C  CZ   . TYR   B 1 57  ? 38.327  -2.960  70.194  1.00 44.42  ?  56  TYR   A CZ   1 
ATOM   5740  O  OH   . TYR   B 1 57  ? 37.259  -2.595  69.385  1.00 48.01  ?  56  TYR   A OH   1 
ATOM   5741  H  H    . TYR   B 1 57  ? 41.751  -2.161  74.209  1.00 53.50  ?  56  TYR   A H    1 
ATOM   5742  H  HA   . TYR   B 1 57  ? 40.440  -4.481  74.298  1.00 47.17  ?  56  TYR   A HA   1 
ATOM   5743  H  HB2  . TYR   B 1 57  ? 42.327  -3.494  72.473  1.00 44.21  ?  56  TYR   A HB2  1 
ATOM   5744  H  HB3  . TYR   B 1 57  ? 41.857  -5.010  72.398  1.00 44.21  ?  56  TYR   A HB3  1 
ATOM   5745  H  HD1  . TYR   B 1 57  ? 39.984  -5.539  71.115  1.00 45.60  ?  56  TYR   A HD1  1 
ATOM   5746  H  HD2  . TYR   B 1 57  ? 40.525  -1.740  72.170  1.00 41.68  ?  56  TYR   A HD2  1 
ATOM   5747  H  HE1  . TYR   B 1 57  ? 38.227  -4.928  69.793  1.00 54.46  ?  56  TYR   A HE1  1 
ATOM   5748  H  HE2  . TYR   B 1 57  ? 38.765  -1.119  70.875  1.00 46.89  ?  56  TYR   A HE2  1 
ATOM   5749  H  HH   . TYR   B 1 57  ? 37.170  -1.760  69.386  1.00 57.61  ?  56  TYR   A HH   1 
ATOM   5750  N  N    . VAL   B 1 58  ? 42.109  -6.197  75.132  1.00 32.83  ?  57  VAL   A N    1 
ATOM   5751  C  CA   . VAL   B 1 58  ? 43.085  -7.146  75.657  1.00 37.73  ?  57  VAL   A CA   1 
ATOM   5752  C  C    . VAL   B 1 58  ? 42.952  -8.434  74.870  1.00 40.43  ?  57  VAL   A C    1 
ATOM   5753  O  O    . VAL   B 1 58  ? 42.018  -8.616  74.100  1.00 44.33  ?  57  VAL   A O    1 
ATOM   5754  C  CB   . VAL   B 1 58  ? 42.895  -7.460  77.152  1.00 39.18  ?  57  VAL   A CB   1 
ATOM   5755  C  CG1  . VAL   B 1 58  ? 43.079  -6.225  77.955  1.00 43.60  ?  57  VAL   A CG1  1 
ATOM   5756  C  CG2  . VAL   B 1 58  ? 41.558  -8.108  77.391  1.00 39.75  ?  57  VAL   A CG2  1 
ATOM   5757  H  H    . VAL   B 1 58  ? 41.331  -6.546  75.019  1.00 39.40  ?  57  VAL   A H    1 
ATOM   5758  H  HA   . VAL   B 1 58  ? 43.968  -6.765  75.535  1.00 45.28  ?  57  VAL   A HA   1 
ATOM   5759  H  HB   . VAL   B 1 58  ? 43.567  -8.096  77.443  1.00 47.01  ?  57  VAL   A HB   1 
ATOM   5760  H  HG11 . VAL   B 1 58  ? 42.947  -6.435  78.892  1.00 52.33  ?  57  VAL   A HG11 1 
ATOM   5761  H  HG12 . VAL   B 1 58  ? 43.978  -5.888  77.815  1.00 52.33  ?  57  VAL   A HG12 1 
ATOM   5762  H  HG13 . VAL   B 1 58  ? 42.430  -5.563  77.669  1.00 52.33  ?  57  VAL   A HG13 1 
ATOM   5763  H  HG21 . VAL   B 1 58  ? 41.452  -8.270  78.341  1.00 47.70  ?  57  VAL   A HG21 1 
ATOM   5764  H  HG22 . VAL   B 1 58  ? 40.859  -7.514  77.076  1.00 47.70  ?  57  VAL   A HG22 1 
ATOM   5765  H  HG23 . VAL   B 1 58  ? 41.523  -8.947  76.906  1.00 47.70  ?  57  VAL   A HG23 1 
ATOM   5766  N  N    . LEU   B 1 59  ? 43.858  -9.360  75.120  1.00 46.30  ?  58  LEU   A N    1 
ATOM   5767  C  CA   . LEU   B 1 59  ? 43.866  -10.656 74.410  1.00 50.01  ?  58  LEU   A CA   1 
ATOM   5768  C  C    . LEU   B 1 59  ? 42.973  -11.663 75.131  1.00 52.08  ?  58  LEU   A C    1 
ATOM   5769  O  O    . LEU   B 1 59  ? 42.938  -11.683 76.359  1.00 48.75  ?  58  LEU   A O    1 
ATOM   5770  C  CB   . LEU   B 1 59  ? 45.272  -11.233 74.317  1.00 49.87  ?  58  LEU   A CB   1 
ATOM   5771  C  CG   . LEU   B 1 59  ? 46.102  -10.728 73.132  1.00 56.27  ?  58  LEU   A CG   1 
ATOM   5772  C  CD1  . LEU   B 1 59  ? 45.948  -9.233  72.987  1.00 51.27  ?  58  LEU   A CD1  1 
ATOM   5773  C  CD2  . LEU   B 1 59  ? 47.580  -11.170 73.322  1.00 52.79  ?  58  LEU   A CD2  1 
ATOM   5774  H  H    . LEU   B 1 59  ? 44.490  -9.277  75.697  1.00 55.56  ?  58  LEU   A H    1 
ATOM   5775  H  HA   . LEU   B 1 59  ? 43.533  -10.519 73.510  1.00 60.02  ?  58  LEU   A HA   1 
ATOM   5776  H  HB2  . LEU   B 1 59  ? 45.752  -11.004 75.128  1.00 59.84  ?  58  LEU   A HB2  1 
ATOM   5777  H  HB3  . LEU   B 1 59  ? 45.202  -12.197 74.234  1.00 59.84  ?  58  LEU   A HB3  1 
ATOM   5778  H  HG   . LEU   B 1 59  ? 45.790  -11.114 72.299  1.00 67.52  ?  58  LEU   A HG   1 
ATOM   5779  H  HD11 . LEU   B 1 59  ? 46.644  -8.899  72.401  1.00 61.52  ?  58  LEU   A HD11 1 
ATOM   5780  H  HD12 . LEU   B 1 59  ? 45.076  -9.041  72.608  1.00 61.52  ?  58  LEU   A HD12 1 
ATOM   5781  H  HD13 . LEU   B 1 59  ? 46.026  -8.821  73.862  1.00 61.52  ?  58  LEU   A HD13 1 
ATOM   5782  H  HD21 . LEU   B 1 59  ? 48.115  -10.798 72.604  1.00 63.35  ?  58  LEU   A HD21 1 
ATOM   5783  H  HD22 . LEU   B 1 59  ? 47.900  -10.844 74.177  1.00 63.35  ?  58  LEU   A HD22 1 
ATOM   5784  H  HD23 . LEU   B 1 59  ? 47.625  -12.139 73.300  1.00 63.35  ?  58  LEU   A HD23 1 
ATOM   5785  N  N    . PRO   B 1 60  ? 42.230  -12.501 74.408  1.00 54.63  ?  59  PRO   A N    1 
ATOM   5786  C  CA   . PRO   B 1 60  ? 41.436  -13.536 75.088  1.00 54.43  ?  59  PRO   A CA   1 
ATOM   5787  C  C    . PRO   B 1 60  ? 42.370  -14.432 75.883  1.00 62.44  ?  59  PRO   A C    1 
ATOM   5788  O  O    . PRO   B 1 60  ? 43.134  -15.199 75.294  1.00 60.56  ?  59  PRO   A O    1 
ATOM   5789  C  CB   . PRO   B 1 60  ? 40.734  -14.284 73.946  1.00 51.64  ?  59  PRO   A CB   1 
ATOM   5790  C  CG   . PRO   B 1 60  ? 40.941  -13.414 72.686  1.00 52.42  ?  59  PRO   A CG   1 
ATOM   5791  C  CD   . PRO   B 1 60  ? 42.216  -12.641 72.941  1.00 56.63  ?  59  PRO   A CD   1 
ATOM   5792  H  HA   . PRO   B 1 60  ? 40.741  -13.162 75.651  1.00 65.31  ?  59  PRO   A HA   1 
ATOM   5793  H  HB2  . PRO   B 1 60  ? 41.137  -15.159 73.831  1.00 61.96  ?  59  PRO   A HB2  1 
ATOM   5794  H  HB3  . PRO   B 1 60  ? 39.790  -14.378 74.149  1.00 61.96  ?  59  PRO   A HB3  1 
ATOM   5795  H  HG2  . PRO   B 1 60  ? 41.032  -13.982 71.905  1.00 62.91  ?  59  PRO   A HG2  1 
ATOM   5796  H  HG3  . PRO   B 1 60  ? 40.189  -12.812 72.574  1.00 62.91  ?  59  PRO   A HG3  1 
ATOM   5797  H  HD2  . PRO   B 1 60  ? 42.990  -13.137 72.633  1.00 67.96  ?  59  PRO   A HD2  1 
ATOM   5798  H  HD3  . PRO   B 1 60  ? 42.186  -11.772 72.511  1.00 67.96  ?  59  PRO   A HD3  1 
ATOM   5799  N  N    . ASN   B 1 61  ? 42.339  -14.315 77.215  1.00 64.90  ?  60  ASN   A N    1 
ATOM   5800  C  CA   . ASN   B 1 61  ? 43.188  -15.099 78.109  1.00 63.49  ?  60  ASN   A CA   1 
ATOM   5801  C  C    . ASN   B 1 61  ? 42.349  -15.925 79.087  1.00 64.86  ?  60  ASN   A C    1 
ATOM   5802  O  O    . ASN   B 1 61  ? 42.835  -16.294 80.161  1.00 62.00  ?  60  ASN   A O    1 
ATOM   5803  C  CB   . ASN   B 1 61  ? 44.173  -14.193 78.867  1.00 58.76  ?  60  ASN   A CB   1 
ATOM   5804  C  CG   . ASN   B 1 61  ? 43.481  -13.276 79.856  1.00 68.04  ?  60  ASN   A CG   1 
ATOM   5805  O  OD1  . ASN   B 1 61  ? 43.398  -12.052 79.641  1.00 62.00  ?  60  ASN   A OD1  1 
ATOM   5806  N  ND2  . ASN   B 1 61  ? 42.967  -13.860 80.952  1.00 75.93  ?  60  ASN   A ND2  1 
ATOM   5807  H  H    . ASN   B 1 61  ? 41.820  -13.772 77.633  1.00 77.88  ?  60  ASN   A H    1 
ATOM   5808  H  HA   . ASN   B 1 61  ? 43.720  -15.712 77.578  1.00 76.19  ?  60  ASN   A HA   1 
ATOM   5809  H  HB2  . ASN   B 1 61  ? 44.798  -14.748 79.359  1.00 70.51  ?  60  ASN   A HB2  1 
ATOM   5810  H  HB3  . ASN   B 1 61  ? 44.650  -13.641 78.229  1.00 70.51  ?  60  ASN   A HB3  1 
ATOM   5811  H  HD21 . ASN   B 1 61  ? 43.042  -14.710 81.061  1.00 91.11  ?  60  ASN   A HD21 1 
ATOM   5812  H  HD22 . ASN   B 1 61  ? 42.564  -13.384 81.544  1.00 91.11  ?  60  ASN   A HD22 1 
ATOM   5813  N  N    . ASP   B 1 62  ? 41.089  -16.205 78.744  1.00 64.42  ?  61  ASP   A N    1 
ATOM   5814  C  CA   . ASP   B 1 62  ? 40.284  -17.191 79.455  1.00 63.55  ?  61  ASP   A CA   1 
ATOM   5815  C  C    . ASP   B 1 62  ? 39.091  -17.553 78.568  1.00 62.94  ?  61  ASP   A C    1 
ATOM   5816  O  O    . ASP   B 1 62  ? 38.810  -16.900 77.557  1.00 61.33  ?  61  ASP   A O    1 
ATOM   5817  C  CB   . ASP   B 1 62  ? 39.889  -16.678 80.848  1.00 68.95  ?  61  ASP   A CB   1 
ATOM   5818  C  CG   . ASP   B 1 62  ? 38.605  -15.867 80.846  1.00 77.64  ?  61  ASP   A CG   1 
ATOM   5819  O  OD1  . ASP   B 1 62  ? 38.434  -14.997 79.958  1.00 72.78  ?  61  ASP   A OD1  1 
ATOM   5820  O  OD2  . ASP   B 1 62  ? 37.759  -16.108 81.737  1.00 80.82  ?  61  ASP   A OD2  1 
ATOM   5821  H  H    . ASP   B 1 62  ? 40.673  -15.828 78.092  1.00 77.31  ?  61  ASP   A H    1 
ATOM   5822  H  HA   . ASP   B 1 62  ? 40.783  -18.011 79.595  1.00 76.26  ?  61  ASP   A HA   1 
ATOM   5823  H  HB2  . ASP   B 1 62  ? 39.761  -17.437 81.438  1.00 82.74  ?  61  ASP   A HB2  1 
ATOM   5824  H  HB3  . ASP   B 1 62  ? 40.599  -16.110 81.186  1.00 82.74  ?  61  ASP   A HB3  1 
ATOM   5825  N  N    . ASP   B 1 63  ? 38.398  -18.619 78.952  1.00 57.23  ?  62  ASP   A N    1 
ATOM   5826  C  CA   . ASP   B 1 63  ? 37.411  -19.203 78.054  1.00 60.04  ?  62  ASP   A CA   1 
ATOM   5827  C  C    . ASP   B 1 63  ? 36.269  -18.235 77.755  1.00 63.43  ?  62  ASP   A C    1 
ATOM   5828  O  O    . ASP   B 1 63  ? 35.759  -18.196 76.628  1.00 52.44  ?  62  ASP   A O    1 
ATOM   5829  C  CB   . ASP   B 1 63  ? 36.889  -20.512 78.649  1.00 56.20  ?  62  ASP   A CB   1 
ATOM   5830  C  CG   . ASP   B 1 63  ? 37.927  -21.623 78.601  1.00 65.38  ?  62  ASP   A CG   1 
ATOM   5831  O  OD1  . ASP   B 1 63  ? 37.545  -22.822 78.580  1.00 60.23  ?  62  ASP   A OD1  1 
ATOM   5832  O  OD2  . ASP   B 1 63  ? 39.136  -21.281 78.575  1.00 65.01  ?  62  ASP   A OD2  1 
ATOM   5833  H  H    . ASP   B 1 63  ? 38.478  -19.016 79.711  1.00 68.67  ?  62  ASP   A H    1 
ATOM   5834  H  HA   . ASP   B 1 63  ? 37.837  -19.405 77.206  1.00 72.04  ?  62  ASP   A HA   1 
ATOM   5835  H  HB2  . ASP   B 1 63  ? 36.647  -20.365 79.577  1.00 67.44  ?  62  ASP   A HB2  1 
ATOM   5836  H  HB3  . ASP   B 1 63  ? 36.112  -20.803 78.146  1.00 67.44  ?  62  ASP   A HB3  1 
ATOM   5837  N  N    . THR   B 1 64  ? 35.839  -17.456 78.748  1.00 68.77  ?  63  THR   A N    1 
ATOM   5838  C  CA   . THR   B 1 64  ? 34.755  -16.518 78.489  1.00 63.87  ?  63  THR   A CA   1 
ATOM   5839  C  C    . THR   B 1 64  ? 35.164  -15.526 77.414  1.00 56.87  ?  63  THR   A C    1 
ATOM   5840  O  O    . THR   B 1 64  ? 34.361  -15.169 76.544  1.00 55.29  ?  63  THR   A O    1 
ATOM   5841  C  CB   . THR   B 1 64  ? 34.364  -15.776 79.766  1.00 69.69  ?  63  THR   A CB   1 
ATOM   5842  O  OG1  . THR   B 1 64  ? 34.481  -16.665 80.879  1.00 88.12  ?  63  THR   A OG1  1 
ATOM   5843  C  CG2  . THR   B 1 64  ? 32.931  -15.252 79.668  1.00 63.50  ?  63  THR   A CG2  1 
ATOM   5844  H  H    . THR   B 1 64  ? 36.149  -17.452 79.551  1.00 82.52  ?  63  THR   A H    1 
ATOM   5845  H  HA   . THR   B 1 64  ? 33.977  -17.014 78.189  1.00 76.64  ?  63  THR   A HA   1 
ATOM   5846  H  HB   . THR   B 1 64  ? 34.950  -15.015 79.898  1.00 83.63  ?  63  THR   A HB   1 
ATOM   5847  H  HG1  . THR   B 1 64  ? 34.309  -16.256 81.593  1.00 105.74 ?  63  THR   A HG1  1 
ATOM   5848  H  HG21 . THR   B 1 64  ? 32.695  -14.777 80.480  1.00 76.20  ?  63  THR   A HG21 1 
ATOM   5849  H  HG22 . THR   B 1 64  ? 32.850  -14.646 78.915  1.00 76.20  ?  63  THR   A HG22 1 
ATOM   5850  H  HG23 . THR   B 1 64  ? 32.315  -15.991 79.545  1.00 76.20  ?  63  THR   A HG23 1 
ATOM   5851  N  N    . LEU   B 1 65  ? 36.417  -15.076 77.456  1.00 56.15  ?  64  LEU   A N    1 
ATOM   5852  C  CA   . LEU   B 1 65  ? 36.850  -14.012 76.561  1.00 54.40  ?  64  LEU   A CA   1 
ATOM   5853  C  C    . LEU   B 1 65  ? 37.091  -14.536 75.150  1.00 49.99  ?  64  LEU   A C    1 
ATOM   5854  O  O    . LEU   B 1 65  ? 36.871  -13.822 74.159  1.00 43.54  ?  64  LEU   A O    1 
ATOM   5855  C  CB   . LEU   B 1 65  ? 38.124  -13.365 77.089  1.00 54.60  ?  64  LEU   A CB   1 
ATOM   5856  C  CG   . LEU   B 1 65  ? 37.918  -12.152 77.988  1.00 59.01  ?  64  LEU   A CG   1 
ATOM   5857  C  CD1  . LEU   B 1 65  ? 39.204  -11.304 78.013  1.00 66.55  ?  64  LEU   A CD1  1 
ATOM   5858  C  CD2  . LEU   B 1 65  ? 36.806  -11.233 77.597  1.00 51.85  ?  64  LEU   A CD2  1 
ATOM   5859  H  H    . LEU   B 1 65  ? 37.027  -15.367 77.988  1.00 67.38  ?  64  LEU   A H    1 
ATOM   5860  H  HA   . LEU   B 1 65  ? 36.154  -13.337 76.527  1.00 65.28  ?  64  LEU   A HA   1 
ATOM   5861  H  HB2  . LEU   B 1 65  ? 38.611  -14.028 77.603  1.00 65.52  ?  64  LEU   A HB2  1 
ATOM   5862  H  HB3  . LEU   B 1 65  ? 38.656  -13.077 76.331  1.00 65.52  ?  64  LEU   A HB3  1 
ATOM   5863  H  HG   . LEU   B 1 65  ? 37.684  -12.524 78.853  1.00 70.81  ?  64  LEU   A HG   1 
ATOM   5864  H  HD11 . LEU   B 1 65  ? 39.060  -10.530 78.580  1.00 79.86  ?  64  LEU   A HD11 1 
ATOM   5865  H  HD12 . LEU   B 1 65  ? 39.930  -11.842 78.366  1.00 79.86  ?  64  LEU   A HD12 1 
ATOM   5866  H  HD13 . LEU   B 1 65  ? 39.412  -11.019 77.110  1.00 79.86  ?  64  LEU   A HD13 1 
ATOM   5867  H  HD21 . LEU   B 1 65  ? 36.815  -10.460 78.183  1.00 62.22  ?  64  LEU   A HD21 1 
ATOM   5868  H  HD22 . LEU   B 1 65  ? 36.936  -10.953 76.678  1.00 62.22  ?  64  LEU   A HD22 1 
ATOM   5869  H  HD23 . LEU   B 1 65  ? 35.962  -11.703 77.684  1.00 62.22  ?  64  LEU   A HD23 1 
ATOM   5870  N  N    . ARG   B 1 66  ? 37.593  -15.755 75.024  1.00 46.53  ?  65  ARG   A N    1 
ATOM   5871  C  CA   . ARG   B 1 66  ? 37.874  -16.210 73.673  1.00 53.12  ?  65  ARG   A CA   1 
ATOM   5872  C  C    . ARG   B 1 66  ? 36.629  -16.740 72.994  1.00 45.50  ?  65  ARG   A C    1 
ATOM   5873  O  O    . ARG   B 1 66  ? 36.620  -16.861 71.772  1.00 47.00  ?  65  ARG   A O    1 
ATOM   5874  C  CB   . ARG   B 1 66  ? 39.018  -17.226 73.657  1.00 58.26  ?  65  ARG   A CB   1 
ATOM   5875  C  CG   . ARG   B 1 66  ? 38.770  -18.566 74.268  1.00 58.79  ?  65  ARG   A CG   1 
ATOM   5876  C  CD   . ARG   B 1 66  ? 40.178  -19.241 74.388  1.00 55.13  ?  65  ARG   A CD   1 
ATOM   5877  N  NE   . ARG   B 1 66  ? 41.001  -18.534 75.364  1.00 59.40  ?  65  ARG   A NE   1 
ATOM   5878  C  CZ   . ARG   B 1 66  ? 41.601  -19.129 76.392  1.00 66.58  ?  65  ARG   A CZ   1 
ATOM   5879  N  NH1  . ARG   B 1 66  ? 42.146  -18.435 77.387  1.00 63.71  ?  65  ARG   A NH1  1 
ATOM   5880  N  NH2  . ARG   B 1 66  ? 41.677  -20.454 76.413  1.00 69.59  ?  65  ARG   A NH2  1 
ATOM   5881  H  H    . ARG   B 1 66  ? 37.768  -16.301 75.664  1.00 55.83  ?  65  ARG   A H    1 
ATOM   5882  H  HA   . ARG   B 1 66  ? 38.200  -15.469 73.139  1.00 63.75  ?  65  ARG   A HA   1 
ATOM   5883  H  HB2  . ARG   B 1 66  ? 39.261  -17.383 72.731  1.00 69.91  ?  65  ARG   A HB2  1 
ATOM   5884  H  HB3  . ARG   B 1 66  ? 39.766  -16.836 74.135  1.00 69.91  ?  65  ARG   A HB3  1 
ATOM   5885  H  HG2  . ARG   B 1 66  ? 38.372  -18.474 75.148  1.00 70.55  ?  65  ARG   A HG2  1 
ATOM   5886  H  HG3  . ARG   B 1 66  ? 38.195  -19.102 73.699  1.00 70.55  ?  65  ARG   A HG3  1 
ATOM   5887  H  HD2  . ARG   B 1 66  ? 40.074  -20.160 74.679  1.00 66.15  ?  65  ARG   A HD2  1 
ATOM   5888  H  HD3  . ARG   B 1 66  ? 40.626  -19.213 73.528  1.00 66.15  ?  65  ARG   A HD3  1 
ATOM   5889  H  HE   . ARG   B 1 66  ? 41.105  -17.686 75.270  1.00 71.28  ?  65  ARG   A HE   1 
ATOM   5890  H  HH11 . ARG   B 1 66  ? 42.118  -17.576 77.378  1.00 76.45  ?  65  ARG   A HH11 1 
ATOM   5891  H  HH12 . ARG   B 1 66  ? 42.528  -18.847 78.039  1.00 76.45  ?  65  ARG   A HH12 1 
ATOM   5892  H  HH21 . ARG   B 1 66  ? 41.343  -20.915 75.768  1.00 83.50  ?  65  ARG   A HH21 1 
ATOM   5893  H  HH22 . ARG   B 1 66  ? 42.062  -20.853 77.071  1.00 83.50  ?  65  ARG   A HH22 1 
ATOM   5894  N  N    . VAL   B 1 67  ? 35.569  -16.996 73.755  1.00 48.38  ?  66  VAL   A N    1 
ATOM   5895  C  CA   . VAL   B 1 67  ? 34.253  -17.183 73.155  1.00 45.31  ?  66  VAL   A CA   1 
ATOM   5896  C  C    . VAL   B 1 67  ? 33.744  -15.864 72.579  1.00 47.22  ?  66  VAL   A C    1 
ATOM   5897  O  O    . VAL   B 1 67  ? 33.285  -15.794 71.431  1.00 39.87  ?  66  VAL   A O    1 
ATOM   5898  C  CB   . VAL   B 1 67  ? 33.273  -17.768 74.191  1.00 49.81  ?  66  VAL   A CB   1 
ATOM   5899  C  CG1  . VAL   B 1 67  ? 31.789  -17.583 73.748  1.00 35.36  ?  66  VAL   A CG1  1 
ATOM   5900  C  CG2  . VAL   B 1 67  ? 33.637  -19.241 74.447  1.00 49.45  ?  66  VAL   A CG2  1 
ATOM   5901  H  H    . VAL   B 1 67  ? 35.584  -17.066 74.612  1.00 58.06  ?  66  VAL   A H    1 
ATOM   5902  H  HA   . VAL   B 1 67  ? 34.329  -17.818 72.426  1.00 54.37  ?  66  VAL   A HA   1 
ATOM   5903  H  HB   . VAL   B 1 67  ? 33.352  -17.286 75.029  1.00 59.77  ?  66  VAL   A HB   1 
ATOM   5904  H  HG11 . VAL   B 1 67  ? 31.223  -18.153 74.293  1.00 42.44  ?  66  VAL   A HG11 1 
ATOM   5905  H  HG12 . VAL   B 1 67  ? 31.537  -16.654 73.869  1.00 42.44  ?  66  VAL   A HG12 1 
ATOM   5906  H  HG13 . VAL   B 1 67  ? 31.705  -17.830 72.814  1.00 42.44  ?  66  VAL   A HG13 1 
ATOM   5907  H  HG21 . VAL   B 1 67  ? 33.405  -19.469 75.361  1.00 59.34  ?  66  VAL   A HG21 1 
ATOM   5908  H  HG22 . VAL   B 1 67  ? 33.140  -19.801 73.830  1.00 59.34  ?  66  VAL   A HG22 1 
ATOM   5909  H  HG23 . VAL   B 1 67  ? 34.589  -19.360 74.308  1.00 59.34  ?  66  VAL   A HG23 1 
ATOM   5910  N  N    . GLU   B 1 68  ? 33.789  -14.798 73.376  1.00 44.90  ?  67  GLU   A N    1 
ATOM   5911  C  CA   . GLU   B 1 68  ? 33.366  -13.504 72.861  1.00 45.73  ?  67  GLU   A CA   1 
ATOM   5912  C  C    . GLU   B 1 68  ? 34.159  -13.142 71.608  1.00 43.22  ?  67  GLU   A C    1 
ATOM   5913  O  O    . GLU   B 1 68  ? 33.592  -12.595 70.656  1.00 39.02  ?  67  GLU   A O    1 
ATOM   5914  C  CB   . GLU   B 1 68  ? 33.496  -12.429 73.951  1.00 42.70  ?  67  GLU   A CB   1 
ATOM   5915  C  CG   . GLU   B 1 68  ? 32.427  -12.555 75.095  1.00 52.69  ?  67  GLU   A CG   1 
ATOM   5916  C  CD   . GLU   B 1 68  ? 32.601  -11.540 76.241  1.00 56.62  ?  67  GLU   A CD   1 
ATOM   5917  O  OE1  . GLU   B 1 68  ? 33.632  -10.818 76.241  1.00 54.76  ?  67  GLU   A OE1  1 
ATOM   5918  O  OE2  . GLU   B 1 68  ? 31.739  -11.505 77.166  1.00 55.53  ?  67  GLU   A OE2  1 
ATOM   5919  H  H    . GLU   B 1 68  ? 34.053  -14.799 74.194  1.00 53.88  ?  67  GLU   A H    1 
ATOM   5920  H  HA   . GLU   B 1 68  ? 32.428  -13.542 72.616  1.00 54.87  ?  67  GLU   A HA   1 
ATOM   5921  H  HB2  . GLU   B 1 68  ? 34.374  -12.501 74.357  1.00 51.25  ?  67  GLU   A HB2  1 
ATOM   5922  H  HB3  . GLU   B 1 68  ? 33.390  -11.556 73.542  1.00 51.25  ?  67  GLU   A HB3  1 
ATOM   5923  H  HG2  . GLU   B 1 68  ? 31.546  -12.418 74.713  1.00 63.22  ?  67  GLU   A HG2  1 
ATOM   5924  H  HG3  . GLU   B 1 68  ? 32.488  -13.444 75.479  1.00 63.22  ?  67  GLU   A HG3  1 
ATOM   5925  N  N    . ALA   B 1 69  ? 35.462  -13.490 71.569  1.00 42.24  ?  68  ALA   A N    1 
ATOM   5926  C  CA   . ALA   B 1 69  ? 36.295  -13.108 70.425  1.00 39.28  ?  68  ALA   A CA   1 
ATOM   5927  C  C    . ALA   B 1 69  ? 35.998  -13.966 69.191  1.00 42.84  ?  68  ALA   A C    1 
ATOM   5928  O  O    . ALA   B 1 69  ? 36.037  -13.464 68.059  1.00 34.72  ?  68  ALA   A O    1 
ATOM   5929  C  CB   . ALA   B 1 69  ? 37.771  -13.202 70.783  1.00 39.35  ?  68  ALA   A CB   1 
ATOM   5930  H  H    . ALA   B 1 69  ? 35.872  -13.935 72.179  1.00 50.69  ?  68  ALA   A H    1 
ATOM   5931  H  HA   . ALA   B 1 69  ? 36.092  -12.185 70.206  1.00 47.13  ?  68  ALA   A HA   1 
ATOM   5932  H  HB1  . ALA   B 1 69  ? 38.300  -12.953 70.009  1.00 47.22  ?  68  ALA   A HB1  1 
ATOM   5933  H  HB2  . ALA   B 1 69  ? 37.956  -12.598 71.519  1.00 47.22  ?  68  ALA   A HB2  1 
ATOM   5934  H  HB3  . ALA   B 1 69  ? 37.975  -14.114 71.043  1.00 47.22  ?  68  ALA   A HB3  1 
ATOM   5935  N  N    . PHE   B 1 70  ? 35.755  -15.272 69.379  1.00 46.68  ?  69  PHE   A N    1 
ATOM   5936  C  CA   . PHE   B 1 70  ? 35.409  -16.130 68.245  1.00 49.70  ?  69  PHE   A CA   1 
ATOM   5937  C  C    . PHE   B 1 70  ? 34.081  -15.695 67.638  1.00 43.19  ?  69  PHE   A C    1 
ATOM   5938  O  O    . PHE   B 1 70  ? 33.925  -15.651 66.413  1.00 41.72  ?  69  PHE   A O    1 
ATOM   5939  C  CB   . PHE   B 1 70  ? 35.334  -17.603 68.672  1.00 48.60  ?  69  PHE   A CB   1 
ATOM   5940  C  CG   . PHE   B 1 70  ? 35.142  -18.580 67.510  1.00 57.45  ?  69  PHE   A CG   1 
ATOM   5941  C  CD1  . PHE   B 1 70  ? 35.337  -18.184 66.190  1.00 60.66  ?  69  PHE   A CD1  1 
ATOM   5942  C  CD2  . PHE   B 1 70  ? 34.786  -19.894 67.742  1.00 57.67  ?  69  PHE   A CD2  1 
ATOM   5943  C  CE1  . PHE   B 1 70  ? 35.158  -19.071 65.132  1.00 54.06  ?  69  PHE   A CE1  1 
ATOM   5944  C  CE2  . PHE   B 1 70  ? 34.622  -20.782 66.690  1.00 94.75  ?  69  PHE   A CE2  1 
ATOM   5945  C  CZ   . PHE   B 1 70  ? 34.806  -20.367 65.386  1.00 55.37  ?  69  PHE   A CZ   1 
ATOM   5946  H  H    . PHE   B 1 70  ? 35.783  -15.674 70.139  1.00 56.02  ?  69  PHE   A H    1 
ATOM   5947  H  HA   . PHE   B 1 70  ? 36.109  -16.056 67.578  1.00 59.63  ?  69  PHE   A HA   1 
ATOM   5948  H  HB2  . PHE   B 1 70  ? 36.160  -17.839 69.122  1.00 58.32  ?  69  PHE   A HB2  1 
ATOM   5949  H  HB3  . PHE   B 1 70  ? 34.583  -17.713 69.277  1.00 58.32  ?  69  PHE   A HB3  1 
ATOM   5950  H  HD1  . PHE   B 1 70  ? 35.593  -17.308 66.011  1.00 72.79  ?  69  PHE   A HD1  1 
ATOM   5951  H  HD2  . PHE   B 1 70  ? 34.655  -20.187 68.615  1.00 69.21  ?  69  PHE   A HD2  1 
ATOM   5952  H  HE1  . PHE   B 1 70  ? 35.276  -18.783 64.256  1.00 64.87  ?  69  PHE   A HE1  1 
ATOM   5953  H  HE2  . PHE   B 1 70  ? 34.386  -21.664 66.864  1.00 113.70 ?  69  PHE   A HE2  1 
ATOM   5954  H  HZ   . PHE   B 1 70  ? 34.691  -20.966 64.684  1.00 66.44  ?  69  PHE   A HZ   1 
ATOM   5955  N  N    . GLU   B 1 71  ? 33.134  -15.318 68.482  1.00 39.15  ?  70  GLU   A N    1 
ATOM   5956  C  CA   . GLU   B 1 71  ? 31.804  -15.004 67.994  1.00 43.14  ?  70  GLU   A CA   1 
ATOM   5957  C  C    . GLU   B 1 71  ? 31.781  -13.678 67.266  1.00 35.81  ?  70  GLU   A C    1 
ATOM   5958  O  O    . GLU   B 1 71  ? 30.923  -13.469 66.400  1.00 35.91  ?  70  GLU   A O    1 
ATOM   5959  C  CB   . GLU   B 1 71  ? 30.809  -14.975 69.157  1.00 38.11  ?  70  GLU   A CB   1 
ATOM   5960  C  CG   . GLU   B 1 71  ? 30.620  -16.319 69.836  1.00 47.12  ?  70  GLU   A CG   1 
ATOM   5961  C  CD   . GLU   B 1 71  ? 29.472  -16.337 70.864  1.00 55.45  ?  70  GLU   A CD   1 
ATOM   5962  O  OE1  . GLU   B 1 71  ? 29.017  -15.250 71.307  1.00 45.43  ?  70  GLU   A OE1  1 
ATOM   5963  O  OE2  . GLU   B 1 71  ? 29.022  -17.452 71.222  1.00 61.81  ?  70  GLU   A OE2  1 
ATOM   5964  H  H    . GLU   B 1 71  ? 33.235  -15.236 69.332  1.00 46.98  ?  70  GLU   A H    1 
ATOM   5965  H  HA   . GLU   B 1 71  ? 31.527  -15.699 67.377  1.00 51.77  ?  70  GLU   A HA   1 
ATOM   5966  H  HB2  . GLU   B 1 71  ? 31.129  -14.349 69.825  1.00 45.73  ?  70  GLU   A HB2  1 
ATOM   5967  H  HB3  . GLU   B 1 71  ? 29.945  -14.690 68.821  1.00 45.73  ?  70  GLU   A HB3  1 
ATOM   5968  H  HG2  . GLU   B 1 71  ? 30.423  -16.986 69.160  1.00 56.55  ?  70  GLU   A HG2  1 
ATOM   5969  H  HG3  . GLU   B 1 71  ? 31.439  -16.551 70.302  1.00 56.55  ?  70  GLU   A HG3  1 
ATOM   5970  N  N    . TYR   B 1 72  ? 32.666  -12.755 67.633  1.00 31.91  ?  71  TYR   A N    1 
ATOM   5971  C  CA   . TYR   B 1 72  ? 32.726  -11.469 66.952  1.00 35.27  ?  71  TYR   A CA   1 
ATOM   5972  C  C    . TYR   B 1 72  ? 33.595  -11.497 65.682  1.00 38.92  ?  71  TYR   A C    1 
ATOM   5973  O  O    . TYR   B 1 72  ? 33.279  -10.807 64.697  1.00 39.72  ?  71  TYR   A O    1 
ATOM   5974  C  CB   . TYR   B 1 72  ? 33.249  -10.410 67.906  1.00 32.48  ?  71  TYR   A CB   1 
ATOM   5975  C  CG   . TYR   B 1 72  ? 32.975  -8.994  67.464  1.00 36.40  ?  71  TYR   A CG   1 
ATOM   5976  C  CD1  . TYR   B 1 72  ? 31.693  -8.481  67.461  1.00 40.29  ?  71  TYR   A CD1  1 
ATOM   5977  C  CD2  . TYR   B 1 72  ? 33.996  -8.154  67.122  1.00 32.49  ?  71  TYR   A CD2  1 
ATOM   5978  C  CE1  . TYR   B 1 72  ? 31.442  -7.164  67.087  1.00 38.56  ?  71  TYR   A CE1  1 
ATOM   5979  C  CE2  . TYR   B 1 72  ? 33.751  -6.846  66.763  1.00 33.47  ?  71  TYR   A CE2  1 
ATOM   5980  C  CZ   . TYR   B 1 72  ? 32.477  -6.360  66.742  1.00 29.88  ?  71  TYR   A CZ   1 
ATOM   5981  O  OH   . TYR   B 1 72  ? 32.222  -5.068  66.364  1.00 41.64  ?  71  TYR   A OH   1 
ATOM   5982  H  H    . TYR   B 1 72  ? 33.237  -12.851 68.269  1.00 38.29  ?  71  TYR   A H    1 
ATOM   5983  H  HA   . TYR   B 1 72  ? 31.830  -11.217 66.681  1.00 42.33  ?  71  TYR   A HA   1 
ATOM   5984  H  HB2  . TYR   B 1 72  ? 32.827  -10.535 68.771  1.00 38.98  ?  71  TYR   A HB2  1 
ATOM   5985  H  HB3  . TYR   B 1 72  ? 34.210  -10.513 67.988  1.00 38.98  ?  71  TYR   A HB3  1 
ATOM   5986  H  HD1  . TYR   B 1 72  ? 30.983  -9.026  67.714  1.00 48.35  ?  71  TYR   A HD1  1 
ATOM   5987  H  HD2  . TYR   B 1 72  ? 34.870  -8.470  67.130  1.00 38.99  ?  71  TYR   A HD2  1 
ATOM   5988  H  HE1  . TYR   B 1 72  ? 30.571  -6.838  67.075  1.00 46.27  ?  71  TYR   A HE1  1 
ATOM   5989  H  HE2  . TYR   B 1 72  ? 34.460  -6.289  66.534  1.00 40.16  ?  71  TYR   A HE2  1 
ATOM   5990  H  HH   . TYR   B 1 72  ? 31.407  -4.978  66.181  1.00 49.97  ?  71  TYR   A HH   1 
ATOM   5991  N  N    . TYR   B 1 73  ? 34.643  -12.312 65.636  1.00 37.89  ?  72  TYR   A N    1 
ATOM   5992  C  CA   . TYR   B 1 73  ? 35.572  -12.265 64.509  1.00 45.79  ?  72  TYR   A CA   1 
ATOM   5993  C  C    . TYR   B 1 73  ? 35.560  -13.495 63.618  1.00 42.72  ?  72  TYR   A C    1 
ATOM   5994  O  O    . TYR   B 1 73  ? 36.040  -13.411 62.485  1.00 46.35  ?  72  TYR   A O    1 
ATOM   5995  C  CB   . TYR   B 1 73  ? 37.001  -12.082 65.020  1.00 34.72  ?  72  TYR   A CB   1 
ATOM   5996  C  CG   . TYR   B 1 73  ? 37.197  -10.783 65.744  1.00 39.12  ?  72  TYR   A CG   1 
ATOM   5997  C  CD1  . TYR   B 1 73  ? 37.122  -9.560  65.064  1.00 35.15  ?  72  TYR   A CD1  1 
ATOM   5998  C  CD2  . TYR   B 1 73  ? 37.469  -10.762 67.122  1.00 38.91  ?  72  TYR   A CD2  1 
ATOM   5999  C  CE1  . TYR   B 1 73  ? 37.324  -8.344  65.742  1.00 40.28  ?  72  TYR   A CE1  1 
ATOM   6000  C  CE2  . TYR   B 1 73  ? 37.655  -9.553  67.800  1.00 38.69  ?  72  TYR   A CE2  1 
ATOM   6001  C  CZ   . TYR   B 1 73  ? 37.565  -8.356  67.112  1.00 39.47  ?  72  TYR   A CZ   1 
ATOM   6002  O  OH   . TYR   B 1 73  ? 37.734  -7.179  67.791  1.00 36.14  ?  72  TYR   A OH   1 
ATOM   6003  H  H    . TYR   B 1 73  ? 34.836  -12.895 66.238  1.00 45.47  ?  72  TYR   A H    1 
ATOM   6004  H  HA   . TYR   B 1 73  ? 35.326  -11.505 63.958  1.00 54.94  ?  72  TYR   A HA   1 
ATOM   6005  H  HB2  . TYR   B 1 73  ? 37.211  -12.802 65.635  1.00 41.66  ?  72  TYR   A HB2  1 
ATOM   6006  H  HB3  . TYR   B 1 73  ? 37.611  -12.100 64.266  1.00 41.66  ?  72  TYR   A HB3  1 
ATOM   6007  H  HD1  . TYR   B 1 73  ? 36.937  -9.552  64.152  1.00 42.17  ?  72  TYR   A HD1  1 
ATOM   6008  H  HD2  . TYR   B 1 73  ? 37.527  -11.564 67.590  1.00 46.70  ?  72  TYR   A HD2  1 
ATOM   6009  H  HE1  . TYR   B 1 73  ? 37.296  -7.539  65.278  1.00 48.34  ?  72  TYR   A HE1  1 
ATOM   6010  H  HE2  . TYR   B 1 73  ? 37.839  -9.554  68.711  1.00 46.43  ?  72  TYR   A HE2  1 
ATOM   6011  H  HH   . TYR   B 1 73  ? 38.035  -7.332  68.561  1.00 43.37  ?  72  TYR   A HH   1 
ATOM   6012  N  N    . HIS   B 1 74  ? 35.018  -14.621 64.090  1.00 41.27  ?  73  HIS   A N    1 
ATOM   6013  C  CA   . HIS   B 1 74  ? 35.021  -15.858 63.323  1.00 45.34  ?  73  HIS   A CA   1 
ATOM   6014  C  C    . HIS   B 1 74  ? 36.456  -16.261 62.993  1.00 48.64  ?  73  HIS   A C    1 
ATOM   6015  O  O    . HIS   B 1 74  ? 36.787  -16.603 61.865  1.00 51.59  ?  73  HIS   A O    1 
ATOM   6016  C  CB   . HIS   B 1 74  ? 34.179  -15.716 62.053  1.00 36.26  ?  73  HIS   A CB   1 
ATOM   6017  C  CG   . HIS   B 1 74  ? 32.716  -15.581 62.312  1.00 45.26  ?  73  HIS   A CG   1 
ATOM   6018  N  ND1  . HIS   B 1 74  ? 31.770  -15.650 61.308  1.00 37.53  ?  73  HIS   A ND1  1 
ATOM   6019  C  CD2  . HIS   B 1 74  ? 32.032  -15.367 63.463  1.00 41.23  ?  73  HIS   A CD2  1 
ATOM   6020  C  CE1  . HIS   B 1 74  ? 30.572  -15.483 61.832  1.00 37.20  ?  73  HIS   A CE1  1 
ATOM   6021  N  NE2  . HIS   B 1 74  ? 30.699  -15.310 63.138  1.00 42.46  ?  73  HIS   A NE2  1 
ATOM   6022  H  H    . HIS   B 1 74  ? 34.640  -14.689 64.859  1.00 49.52  ?  73  HIS   A H    1 
ATOM   6023  H  HA   . HIS   B 1 74  ? 34.625  -16.566 63.856  1.00 54.41  ?  73  HIS   A HA   1 
ATOM   6024  H  HB2  . HIS   B 1 74  ? 34.468  -14.924 61.574  1.00 43.51  ?  73  HIS   A HB2  1 
ATOM   6025  H  HB3  . HIS   B 1 74  ? 34.310  -16.503 61.502  1.00 43.51  ?  73  HIS   A HB3  1 
ATOM   6026  H  HD2  . HIS   B 1 74  ? 32.398  -15.276 64.313  1.00 49.47  ?  73  HIS   A HD2  1 
ATOM   6027  H  HE1  . HIS   B 1 74  ? 29.770  -15.486 61.361  1.00 44.64  ?  73  HIS   A HE1  1 
ATOM   6028  H  HE2  . HIS   B 1 74  ? 30.054  -15.183 63.692  1.00 50.95  ?  73  HIS   A HE2  1 
ATOM   6029  N  N    . THR   B 1 75  ? 37.311  -16.210 64.003  1.00 47.04  ?  74  THR   A N    1 
ATOM   6030  C  CA   . THR   B 1 75  ? 38.673  -16.690 63.872  1.00 43.28  ?  74  THR   A CA   1 
ATOM   6031  C  C    . THR   B 1 75  ? 39.207  -16.995 65.265  1.00 43.21  ?  74  THR   A C    1 
ATOM   6032  O  O    . THR   B 1 75  ? 38.972  -16.240 66.216  1.00 43.10  ?  74  THR   A O    1 
ATOM   6033  C  CB   . THR   B 1 75  ? 39.551  -15.655 63.161  1.00 48.32  ?  74  THR   A CB   1 
ATOM   6034  O  OG1  . THR   B 1 75  ? 40.915  -16.110 63.066  1.00 47.17  ?  74  THR   A OG1  1 
ATOM   6035  C  CG2  . THR   B 1 75  ? 39.505  -14.356 63.901  1.00 38.60  ?  74  THR   A CG2  1 
ATOM   6036  H  H    . THR   B 1 75  ? 37.123  -15.899 64.783  1.00 56.45  ?  74  THR   A H    1 
ATOM   6037  H  HA   . THR   B 1 75  ? 38.696  -17.510 63.353  1.00 51.94  ?  74  THR   A HA   1 
ATOM   6038  H  HB   . THR   B 1 75  ? 39.216  -15.521 62.260  1.00 57.98  ?  74  THR   A HB   1 
ATOM   6039  H  HG1  . THR   B 1 75  ? 41.364  -15.577 62.597  1.00 56.60  ?  74  THR   A HG1  1 
ATOM   6040  H  HG21 . THR   B 1 75  ? 39.963  -13.668 63.393  1.00 46.32  ?  74  THR   A HG21 1 
ATOM   6041  H  HG22 . THR   B 1 75  ? 38.584  -14.085 64.039  1.00 46.32  ?  74  THR   A HG22 1 
ATOM   6042  H  HG23 . THR   B 1 75  ? 39.938  -14.451 64.764  1.00 46.32  ?  74  THR   A HG23 1 
ATOM   6043  N  N    . THR   B 1 76  ? 39.938  -18.099 65.368  1.00 53.50  ?  75  THR   A N    1 
ATOM   6044  C  CA   . THR   B 1 76  ? 40.594  -18.510 66.602  1.00 53.11  ?  75  THR   A CA   1 
ATOM   6045  C  C    . THR   B 1 76  ? 42.063  -18.128 66.642  1.00 51.83  ?  75  THR   A C    1 
ATOM   6046  O  O    . THR   B 1 76  ? 42.731  -18.412 67.643  1.00 57.07  ?  75  THR   A O    1 
ATOM   6047  C  CB   . THR   B 1 76  ? 40.455  -20.019 66.769  1.00 55.09  ?  75  THR   A CB   1 
ATOM   6048  O  OG1  . THR   B 1 76  ? 40.691  -20.644 65.501  1.00 61.77  ?  75  THR   A OG1  1 
ATOM   6049  C  CG2  . THR   B 1 76  ? 39.043  -20.366 67.239  1.00 55.33  ?  75  THR   A CG2  1 
ATOM   6050  H  H    . THR   B 1 76  ? 40.072  -18.643 64.716  1.00 64.20  ?  75  THR   A H    1 
ATOM   6051  H  HA   . THR   B 1 76  ? 40.158  -18.077 67.353  1.00 63.73  ?  75  THR   A HA   1 
ATOM   6052  H  HB   . THR   B 1 76  ? 41.090  -20.345 67.426  1.00 66.11  ?  75  THR   A HB   1 
ATOM   6053  H  HG1  . THR   B 1 76  ? 40.521  -21.465 65.549  1.00 74.12  ?  75  THR   A HG1  1 
ATOM   6054  H  HG21 . THR   B 1 76  ? 38.932  -21.329 67.273  1.00 66.40  ?  75  THR   A HG21 1 
ATOM   6055  H  HG22 . THR   B 1 76  ? 38.888  -20.000 68.124  1.00 66.40  ?  75  THR   A HG22 1 
ATOM   6056  H  HG23 . THR   B 1 76  ? 38.389  -19.996 66.626  1.00 66.40  ?  75  THR   A HG23 1 
ATOM   6057  N  N    . ASP   B 1 77  ? 42.571  -17.469 65.599  1.00 49.97  ?  76  ASP   A N    1 
ATOM   6058  C  CA   . ASP   B 1 77  ? 43.990  -17.137 65.487  1.00 51.06  ?  76  ASP   A CA   1 
ATOM   6059  C  C    . ASP   B 1 77  ? 44.464  -16.266 66.648  1.00 52.51  ?  76  ASP   A C    1 
ATOM   6060  O  O    . ASP   B 1 77  ? 44.039  -15.103 66.755  1.00 46.58  ?  76  ASP   A O    1 
ATOM   6061  C  CB   . ASP   B 1 77  ? 44.243  -16.418 64.146  1.00 50.93  ?  76  ASP   A CB   1 
ATOM   6062  C  CG   . ASP   B 1 77  ? 45.725  -16.026 63.933  1.00 59.40  ?  76  ASP   A CG   1 
ATOM   6063  O  OD1  . ASP   B 1 77  ? 46.566  -16.253 64.848  1.00 52.77  ?  76  ASP   A OD1  1 
ATOM   6064  O  OD2  . ASP   B 1 77  ? 46.030  -15.475 62.841  1.00 53.48  ?  76  ASP   A OD2  1 
ATOM   6065  H  H    . ASP   B 1 77  ? 42.104  -17.199 64.929  1.00 59.96  ?  76  ASP   A H    1 
ATOM   6066  H  HA   . ASP   B 1 77  ? 44.504  -17.958 65.518  1.00 61.27  ?  76  ASP   A HA   1 
ATOM   6067  H  HB2  . ASP   B 1 77  ? 43.984  -17.007 63.421  1.00 61.11  ?  76  ASP   A HB2  1 
ATOM   6068  H  HB3  . ASP   B 1 77  ? 43.714  -15.606 64.120  1.00 61.11  ?  76  ASP   A HB3  1 
ATOM   6069  N  N    . PRO   B 1 78  ? 45.407  -16.743 67.469  1.00 52.57  ?  77  PRO   A N    1 
ATOM   6070  C  CA   . PRO   B 1 78  ? 45.789  -15.960 68.655  1.00 50.58  ?  77  PRO   A CA   1 
ATOM   6071  C  C    . PRO   B 1 78  ? 46.429  -14.650 68.303  1.00 47.00  ?  77  PRO   A C    1 
ATOM   6072  O  O    . PRO   B 1 78  ? 46.346  -13.714 69.106  1.00 45.10  ?  77  PRO   A O    1 
ATOM   6073  C  CB   . PRO   B 1 78  ? 46.764  -16.875 69.415  1.00 49.76  ?  77  PRO   A CB   1 
ATOM   6074  C  CG   . PRO   B 1 78  ? 46.674  -18.234 68.711  1.00 59.75  ?  77  PRO   A CG   1 
ATOM   6075  C  CD   . PRO   B 1 78  ? 46.234  -17.949 67.302  1.00 45.43  ?  77  PRO   A CD   1 
ATOM   6076  H  HA   . PRO   B 1 78  ? 45.010  -15.813 69.212  1.00 60.69  ?  77  PRO   A HA   1 
ATOM   6077  H  HB2  . PRO   B 1 78  ? 47.663  -16.516 69.360  1.00 59.71  ?  77  PRO   A HB2  1 
ATOM   6078  H  HB3  . PRO   B 1 78  ? 46.491  -16.947 70.343  1.00 59.71  ?  77  PRO   A HB3  1 
ATOM   6079  H  HG2  . PRO   B 1 78  ? 47.544  -18.663 68.718  1.00 71.70  ?  77  PRO   A HG2  1 
ATOM   6080  H  HG3  . PRO   B 1 78  ? 46.024  -18.794 69.165  1.00 71.70  ?  77  PRO   A HG3  1 
ATOM   6081  H  HD2  . PRO   B 1 78  ? 46.996  -17.773 66.728  1.00 54.52  ?  77  PRO   A HD2  1 
ATOM   6082  H  HD3  . PRO   B 1 78  ? 45.712  -18.684 66.944  1.00 54.52  ?  77  PRO   A HD3  1 
ATOM   6083  N  N    . SER   B 1 79  ? 47.053  -14.551 67.127  1.00 45.11  ?  78  SER   A N    1 
ATOM   6084  C  CA   . SER   B 1 79  ? 47.745  -13.335 66.713  1.00 49.18  ?  78  SER   A CA   1 
ATOM   6085  C  C    . SER   B 1 79  ? 46.821  -12.269 66.153  1.00 49.93  ?  78  SER   A C    1 
ATOM   6086  O  O    . SER   B 1 79  ? 47.271  -11.125 65.959  1.00 43.44  ?  78  SER   A O    1 
ATOM   6087  C  CB   . SER   B 1 79  ? 48.776  -13.660 65.647  1.00 55.47  ?  78  SER   A CB   1 
ATOM   6088  O  OG   . SER   B 1 79  ? 48.144  -13.881 64.402  1.00 56.14  ?  78  SER   A OG   1 
ATOM   6089  H  H    . SER   B 1 79  ? 47.089  -15.183 66.545  1.00 54.13  ?  78  SER   A H    1 
ATOM   6090  H  HA   . SER   B 1 79  ? 48.191  -12.974 67.495  1.00 59.01  ?  78  SER   A HA   1 
ATOM   6091  H  HB2  . SER   B 1 79  ? 49.391  -12.915 65.563  1.00 66.57  ?  78  SER   A HB2  1 
ATOM   6092  H  HB3  . SER   B 1 79  ? 49.258  -14.461 65.906  1.00 66.57  ?  78  SER   A HB3  1 
ATOM   6093  H  HG   . SER   B 1 79  ? 48.709  -13.838 63.782  1.00 67.36  ?  78  SER   A HG   1 
ATOM   6094  N  N    . PHE   B 1 80  ? 45.563  -12.629 65.876  1.00 45.61  ?  79  PHE   A N    1 
ATOM   6095  C  CA   . PHE   B 1 80  ? 44.677  -11.761 65.104  1.00 46.64  ?  79  PHE   A CA   1 
ATOM   6096  C  C    . PHE   B 1 80  ? 44.510  -10.403 65.783  1.00 49.07  ?  79  PHE   A C    1 
ATOM   6097  O  O    . PHE   B 1 80  ? 44.724  -9.355  65.155  1.00 46.81  ?  79  PHE   A O    1 
ATOM   6098  C  CB   . PHE   B 1 80  ? 43.298  -12.434 64.892  1.00 44.22  ?  79  PHE   A CB   1 
ATOM   6099  C  CG   . PHE   B 1 80  ? 42.336  -11.595 64.101  1.00 42.66  ?  79  PHE   A CG   1 
ATOM   6100  C  CD1  . PHE   B 1 80  ? 41.437  -10.765 64.720  1.00 39.31  ?  79  PHE   A CD1  1 
ATOM   6101  C  CD2  . PHE   B 1 80  ? 42.336  -11.646 62.734  1.00 44.63  ?  79  PHE   A CD2  1 
ATOM   6102  C  CE1  . PHE   B 1 80  ? 40.593  -9.977  63.984  1.00 36.80  ?  79  PHE   A CE1  1 
ATOM   6103  C  CE2  . PHE   B 1 80  ? 41.449  -10.875 61.997  1.00 36.27  ?  79  PHE   A CE2  1 
ATOM   6104  C  CZ   . PHE   B 1 80  ? 40.618  -10.026 62.626  1.00 36.25  ?  79  PHE   A CZ   1 
ATOM   6105  H  H    . PHE   B 1 80  ? 45.201  -13.369 66.124  1.00 54.73  ?  79  PHE   A H    1 
ATOM   6106  H  HA   . PHE   B 1 80  ? 45.074  -11.621 64.230  1.00 55.96  ?  79  PHE   A HA   1 
ATOM   6107  H  HB2  . PHE   B 1 80  ? 43.428  -13.268 64.414  1.00 53.06  ?  79  PHE   A HB2  1 
ATOM   6108  H  HB3  . PHE   B 1 80  ? 42.898  -12.607 65.759  1.00 53.06  ?  79  PHE   A HB3  1 
ATOM   6109  H  HD1  . PHE   B 1 80  ? 41.401  -10.737 65.649  1.00 47.18  ?  79  PHE   A HD1  1 
ATOM   6110  H  HD2  . PHE   B 1 80  ? 42.937  -12.203 62.295  1.00 53.56  ?  79  PHE   A HD2  1 
ATOM   6111  H  HE1  . PHE   B 1 80  ? 40.000  -9.405  64.416  1.00 44.16  ?  79  PHE   A HE1  1 
ATOM   6112  H  HE2  . PHE   B 1 80  ? 41.430  -10.946 61.070  1.00 43.52  ?  79  PHE   A HE2  1 
ATOM   6113  H  HZ   . PHE   B 1 80  ? 40.059  -9.472  62.131  1.00 43.51  ?  79  PHE   A HZ   1 
ATOM   6114  N  N    . LEU   B 1 81  ? 44.131  -10.400 67.075  1.00 38.75  ?  80  LEU   A N    1 
ATOM   6115  C  CA   . LEU   B 1 81  ? 43.827  -9.139  67.754  1.00 36.97  ?  80  LEU   A CA   1 
ATOM   6116  C  C    . LEU   B 1 81  ? 44.982  -8.149  67.644  1.00 42.95  ?  80  LEU   A C    1 
ATOM   6117  O  O    . LEU   B 1 81  ? 44.781  -6.958  67.360  1.00 37.12  ?  80  LEU   A O    1 
ATOM   6118  C  CB   . LEU   B 1 81  ? 43.511  -9.384  69.237  1.00 47.87  ?  80  LEU   A CB   1 
ATOM   6119  C  CG   . LEU   B 1 81  ? 42.019  -9.263  69.576  1.00 51.42  ?  80  LEU   A CG   1 
ATOM   6120  C  CD1  . LEU   B 1 81  ? 41.556  -7.853  69.329  1.00 42.84  ?  80  LEU   A CD1  1 
ATOM   6121  C  CD2  . LEU   B 1 81  ? 41.323  -10.303 68.701  1.00 61.50  ?  80  LEU   A CD2  1 
ATOM   6122  H  H    . LEU   B 1 81  ? 44.046  -11.101 67.565  1.00 46.50  ?  80  LEU   A H    1 
ATOM   6123  H  HA   . LEU   B 1 81  ? 43.044  -8.758  67.327  1.00 44.37  ?  80  LEU   A HA   1 
ATOM   6124  H  HB2  . LEU   B 1 81  ? 43.798  -10.280 69.473  1.00 57.45  ?  80  LEU   A HB2  1 
ATOM   6125  H  HB3  . LEU   B 1 81  ? 43.991  -8.731  69.770  1.00 57.45  ?  80  LEU   A HB3  1 
ATOM   6126  H  HG   . LEU   B 1 81  ? 41.806  -9.434  70.507  1.00 61.70  ?  80  LEU   A HG   1 
ATOM   6127  H  HD11 . LEU   B 1 81  ? 40.613  -7.787  69.546  1.00 51.41  ?  80  LEU   A HD11 1 
ATOM   6128  H  HD12 . LEU   B 1 81  ? 42.068  -7.250  69.891  1.00 51.41  ?  80  LEU   A HD12 1 
ATOM   6129  H  HD13 . LEU   B 1 81  ? 41.697  -7.633  68.395  1.00 51.41  ?  80  LEU   A HD13 1 
ATOM   6130  H  HD21 . LEU   B 1 81  ? 40.369  -10.274 68.873  1.00 73.80  ?  80  LEU   A HD21 1 
ATOM   6131  H  HD22 . LEU   B 1 81  ? 41.498  -10.100 67.769  1.00 73.80  ?  80  LEU   A HD22 1 
ATOM   6132  H  HD23 . LEU   B 1 81  ? 41.671  -11.182 68.918  1.00 73.80  ?  80  LEU   A HD23 1 
ATOM   6133  N  N    . GLY   B 1 82  ? 46.203  -8.625  67.917  1.00 41.11  ?  81  GLY   A N    1 
ATOM   6134  C  CA   . GLY   B 1 82  ? 47.353  -7.748  67.863  1.00 39.18  ?  81  GLY   A CA   1 
ATOM   6135  C  C    . GLY   B 1 82  ? 47.555  -7.124  66.496  1.00 44.90  ?  81  GLY   A C    1 
ATOM   6136  O  O    . GLY   B 1 82  ? 47.838  -5.930  66.384  1.00 47.07  ?  81  GLY   A O    1 
ATOM   6137  H  H    . GLY   B 1 82  ? 46.380  -9.439  68.131  1.00 49.33  ?  81  GLY   A H    1 
ATOM   6138  H  HA2  . GLY   B 1 82  ? 47.240  -7.033  68.509  1.00 47.01  ?  81  GLY   A HA2  1 
ATOM   6139  H  HA3  . GLY   B 1 82  ? 48.150  -8.252  68.087  1.00 47.01  ?  81  GLY   A HA3  1 
ATOM   6140  N  N    . ARG   B 1 83  ? 47.442  -7.922  65.435  1.00 50.07  ?  82  ARG   A N    1 
ATOM   6141  C  CA   . ARG   B 1 83  ? 47.621  -7.358  64.099  1.00 48.33  ?  82  ARG   A CA   1 
ATOM   6142  C  C    . ARG   B 1 83  ? 46.534  -6.329  63.801  1.00 37.49  ?  82  ARG   A C    1 
ATOM   6143  O  O    . ARG   B 1 83  ? 46.810  -5.285  63.208  1.00 36.05  ?  82  ARG   A O    1 
ATOM   6144  C  CB   . ARG   B 1 83  ? 47.622  -8.462  63.042  1.00 48.42  ?  82  ARG   A CB   1 
ATOM   6145  C  CG   . ARG   B 1 83  ? 48.663  -9.536  63.259  1.00 44.59  ?  82  ARG   A CG   1 
ATOM   6146  C  CD   . ARG   B 1 83  ? 48.710  -10.477 62.050  1.00 42.85  ?  82  ARG   A CD   1 
ATOM   6147  N  NE   . ARG   B 1 83  ? 47.896  -11.664 62.271  1.00 48.07  ?  82  ARG   A NE   1 
ATOM   6148  C  CZ   . ARG   B 1 83  ? 46.716  -11.863 61.705  1.00 47.79  ?  82  ARG   A CZ   1 
ATOM   6149  N  NH1  . ARG   B 1 83  ? 46.207  -10.995 60.848  1.00 45.23  ?  82  ARG   A NH1  1 
ATOM   6150  N  NH2  . ARG   B 1 83  ? 46.027  -12.954 62.013  1.00 53.83  ?  82  ARG   A NH2  1 
ATOM   6151  H  H    . ARG   B 1 83  ? 47.268  -8.764  65.461  1.00 60.08  ?  82  ARG   A H    1 
ATOM   6152  H  HA   . ARG   B 1 83  ? 48.484  -6.919  64.058  1.00 58.00  ?  82  ARG   A HA   1 
ATOM   6153  H  HB2  . ARG   B 1 83  ? 46.753  -8.892  63.043  1.00 58.11  ?  82  ARG   A HB2  1 
ATOM   6154  H  HB3  . ARG   B 1 83  ? 47.793  -8.059  62.176  1.00 58.11  ?  82  ARG   A HB3  1 
ATOM   6155  H  HG2  . ARG   B 1 83  ? 49.536  -9.128  63.368  1.00 53.51  ?  82  ARG   A HG2  1 
ATOM   6156  H  HG3  . ARG   B 1 83  ? 48.438  -10.055 64.047  1.00 53.51  ?  82  ARG   A HG3  1 
ATOM   6157  H  HD2  . ARG   B 1 83  ? 48.369  -10.014 61.269  1.00 51.42  ?  82  ARG   A HD2  1 
ATOM   6158  H  HD3  . ARG   B 1 83  ? 49.625  -10.758 61.896  1.00 51.42  ?  82  ARG   A HD3  1 
ATOM   6159  H  HE   . ARG   B 1 83  ? 48.200  -12.271 62.799  1.00 57.68  ?  82  ARG   A HE   1 
ATOM   6160  H  HH11 . ARG   B 1 83  ? 46.645  -10.282 60.646  1.00 54.28  ?  82  ARG   A HH11 1 
ATOM   6161  H  HH12 . ARG   B 1 83  ? 45.439  -11.143 60.491  1.00 54.28  ?  82  ARG   A HH12 1 
ATOM   6162  H  HH21 . ARG   B 1 83  ? 46.348  -13.521 62.574  1.00 64.60  ?  82  ARG   A HH21 1 
ATOM   6163  H  HH22 . ARG   B 1 83  ? 45.259  -13.094 61.652  1.00 64.60  ?  82  ARG   A HH22 1 
ATOM   6164  N  N    . TYR   B 1 84  ? 45.296  -6.588  64.242  1.00 40.99  ?  83  TYR   A N    1 
ATOM   6165  C  CA   . TYR   B 1 84  ? 44.199  -5.639  63.999  1.00 38.21  ?  83  TYR   A CA   1 
ATOM   6166  C  C    . TYR   B 1 84  ? 44.467  -4.306  64.689  1.00 35.75  ?  83  TYR   A C    1 
ATOM   6167  O  O    . TYR   B 1 84  ? 44.286  -3.238  64.095  1.00 37.68  ?  83  TYR   A O    1 
ATOM   6168  C  CB   . TYR   B 1 84  ? 42.868  -6.255  64.447  1.00 34.27  ?  83  TYR   A CB   1 
ATOM   6169  C  CG   . TYR   B 1 84  ? 41.637  -5.320  64.569  1.00 34.37  ?  83  TYR   A CG   1 
ATOM   6170  C  CD1  . TYR   B 1 84  ? 41.420  -4.275  63.701  1.00 33.47  ?  83  TYR   A CD1  1 
ATOM   6171  C  CD2  . TYR   B 1 84  ? 40.717  -5.513  65.560  1.00 32.46  ?  83  TYR   A CD2  1 
ATOM   6172  C  CE1  . TYR   B 1 84  ? 40.317  -3.448  63.819  1.00 34.24  ?  83  TYR   A CE1  1 
ATOM   6173  C  CE2  . TYR   B 1 84  ? 39.612  -4.703  65.695  1.00 38.43  ?  83  TYR   A CE2  1 
ATOM   6174  C  CZ   . TYR   B 1 84  ? 39.418  -3.666  64.833  1.00 37.85  ?  83  TYR   A CZ   1 
ATOM   6175  O  OH   . TYR   B 1 84  ? 38.328  -2.854  64.994  1.00 35.30  ?  83  TYR   A OH   1 
ATOM   6176  H  H    . TYR   B 1 84  ? 45.067  -7.293  64.677  1.00 49.19  ?  83  TYR   A H    1 
ATOM   6177  H  HA   . TYR   B 1 84  ? 44.127  -5.462  63.048  1.00 45.85  ?  83  TYR   A HA   1 
ATOM   6178  H  HB2  . TYR   B 1 84  ? 42.632  -6.943  63.806  1.00 41.12  ?  83  TYR   A HB2  1 
ATOM   6179  H  HB3  . TYR   B 1 84  ? 43.005  -6.649  65.322  1.00 41.12  ?  83  TYR   A HB3  1 
ATOM   6180  H  HD1  . TYR   B 1 84  ? 42.031  -4.120  63.017  1.00 40.16  ?  83  TYR   A HD1  1 
ATOM   6181  H  HD2  . TYR   B 1 84  ? 40.841  -6.212  66.162  1.00 38.95  ?  83  TYR   A HD2  1 
ATOM   6182  H  HE1  . TYR   B 1 84  ? 40.186  -2.751  63.218  1.00 41.08  ?  83  TYR   A HE1  1 
ATOM   6183  H  HE2  . TYR   B 1 84  ? 38.998  -4.864  66.375  1.00 46.12  ?  83  TYR   A HE2  1 
ATOM   6184  H  HH   . TYR   B 1 84  ? 38.028  -2.624  64.244  1.00 42.36  ?  83  TYR   A HH   1 
ATOM   6185  N  N    . MET   B 1 85  ? 44.978  -4.339  65.904  1.00 36.12  ?  84  MET   A N    1 
ATOM   6186  C  CA   . MET   B 1 85  ? 45.275  -3.089  66.587  1.00 39.39  ?  84  MET   A CA   1 
ATOM   6187  C  C    . MET   B 1 85  ? 46.495  -2.406  65.987  1.00 40.98  ?  84  MET   A C    1 
ATOM   6188  O  O    . MET   B 1 85  ? 46.503  -1.180  65.808  1.00 38.01  ?  84  MET   A O    1 
ATOM   6189  C  CB   . MET   B 1 85  ? 45.469  -3.368  68.078  1.00 41.51  ?  84  MET   A CB   1 
ATOM   6190  C  CG   . MET   B 1 85  ? 44.240  -3.987  68.720  1.00 45.93  ?  84  MET   A CG   1 
ATOM   6191  S  SD   . MET   B 1 85  ? 43.135  -2.644  69.238  1.00 51.08  ?  84  MET   A SD   1 
ATOM   6192  C  CE   . MET   B 1 85  ? 41.550  -3.181  68.786  1.00 49.76  ?  84  MET   A CE   1 
ATOM   6193  H  H    . MET   B 1 85  ? 45.160  -5.053  66.349  1.00 43.35  ?  84  MET   A H    1 
ATOM   6194  H  HA   . MET   B 1 85  ? 44.522  -2.485  66.493  1.00 47.27  ?  84  MET   A HA   1 
ATOM   6195  H  HB2  . MET   B 1 85  ? 46.211  -3.983  68.191  1.00 49.82  ?  84  MET   A HB2  1 
ATOM   6196  H  HB3  . MET   B 1 85  ? 45.659  -2.533  68.533  1.00 49.82  ?  84  MET   A HB3  1 
ATOM   6197  H  HG2  . MET   B 1 85  ? 43.778  -4.551  68.081  1.00 55.12  ?  84  MET   A HG2  1 
ATOM   6198  H  HG3  . MET   B 1 85  ? 44.496  -4.507  69.498  1.00 55.12  ?  84  MET   A HG3  1 
ATOM   6199  H  HE1  . MET   B 1 85  ? 40.894  -2.563  69.143  1.00 59.71  ?  84  MET   A HE1  1 
ATOM   6200  H  HE2  . MET   B 1 85  ? 41.489  -3.206  67.819  1.00 59.71  ?  84  MET   A HE2  1 
ATOM   6201  H  HE3  . MET   B 1 85  ? 41.402  -4.068  69.151  1.00 59.71  ?  84  MET   A HE3  1 
ATOM   6202  N  N    . SER   B 1 86  ? 47.547  -3.178  65.678  1.00 39.98  ?  85  SER   A N    1 
ATOM   6203  C  CA   . SER   B 1 86  ? 48.704  -2.591  65.017  1.00 34.96  ?  85  SER   A CA   1 
ATOM   6204  C  C    . SER   B 1 86  ? 48.265  -1.837  63.778  1.00 38.01  ?  85  SER   A C    1 
ATOM   6205  O  O    . SER   B 1 86  ? 48.588  -0.656  63.610  1.00 38.18  ?  85  SER   A O    1 
ATOM   6206  C  CB   . SER   B 1 86  ? 49.712  -3.672  64.665  1.00 38.25  ?  85  SER   A CB   1 
ATOM   6207  O  OG   . SER   B 1 86  ? 49.712  -4.630  65.704  1.00 44.59  ?  85  SER   A OG   1 
ATOM   6208  H  H    . SER   B 1 86  ? 47.608  -4.021  65.840  1.00 47.98  ?  85  SER   A H    1 
ATOM   6209  H  HA   . SER   B 1 86  ? 49.143  -1.972  65.620  1.00 41.95  ?  85  SER   A HA   1 
ATOM   6210  H  HB2  . SER   B 1 86  ? 49.457  -4.096  63.830  1.00 45.90  ?  85  SER   A HB2  1 
ATOM   6211  H  HB3  . SER   B 1 86  ? 50.595  -3.281  64.582  1.00 45.90  ?  85  SER   A HB3  1 
ATOM   6212  H  HG   . SER   B 1 86  ? 48.998  -5.072  65.688  1.00 53.50  ?  85  SER   A HG   1 
ATOM   6213  N  N    . ALA   B 1 87  ? 47.489  -2.495  62.913  1.00 38.24  ?  86  ALA   A N    1 
ATOM   6214  C  CA   . ALA   B 1 87  ? 46.969  -1.810  61.741  1.00 32.95  ?  86  ALA   A CA   1 
ATOM   6215  C  C    . ALA   B 1 87  ? 46.139  -0.590  62.141  1.00 36.18  ?  86  ALA   A C    1 
ATOM   6216  O  O    . ALA   B 1 87  ? 46.299  0.502   61.561  1.00 30.76  ?  86  ALA   A O    1 
ATOM   6217  C  CB   . ALA   B 1 87  ? 46.145  -2.787  60.899  1.00 41.31  ?  86  ALA   A CB   1 
ATOM   6218  H  H    . ALA   B 1 87  ? 47.256  -3.320  62.984  1.00 45.89  ?  86  ALA   A H    1 
ATOM   6219  H  HA   . ALA   B 1 87  ? 47.710  -1.496  61.199  1.00 39.54  ?  86  ALA   A HA   1 
ATOM   6220  H  HB1  . ALA   B 1 87  ? 45.789  -2.317  60.128  1.00 49.57  ?  86  ALA   A HB1  1 
ATOM   6221  H  HB2  . ALA   B 1 87  ? 46.718  -3.513  60.607  1.00 49.57  ?  86  ALA   A HB2  1 
ATOM   6222  H  HB3  . ALA   B 1 87  ? 45.419  -3.135  61.439  1.00 49.57  ?  86  ALA   A HB3  1 
ATOM   6223  N  N    . LEU   B 1 88  ? 45.214  -0.770  63.108  1.00 35.76  ?  87  LEU   A N    1 
ATOM   6224  C  CA   . LEU   B 1 88  ? 44.277  0.301   63.449  1.00 30.00  ?  87  LEU   A CA   1 
ATOM   6225  C  C    . LEU   B 1 88  ? 45.014  1.533   63.925  1.00 31.53  ?  87  LEU   A C    1 
ATOM   6226  O  O    . LEU   B 1 88  ? 44.560  2.657   63.705  1.00 33.90  ?  87  LEU   A O    1 
ATOM   6227  C  CB   . LEU   B 1 88  ? 43.299  -0.171  64.517  1.00 34.47  ?  87  LEU   A CB   1 
ATOM   6228  C  CG   . LEU   B 1 88  ? 42.323  0.904   64.999  1.00 40.12  ?  87  LEU   A CG   1 
ATOM   6229  C  CD1  . LEU   B 1 88  ? 41.343  1.370   63.914  1.00 38.24  ?  87  LEU   A CD1  1 
ATOM   6230  C  CD2  . LEU   B 1 88  ? 41.578  0.389   66.255  1.00 40.50  ?  87  LEU   A CD2  1 
ATOM   6231  H  H    . LEU   B 1 88  ? 45.116  -1.490  63.567  1.00 42.91  ?  87  LEU   A H    1 
ATOM   6232  H  HA   . LEU   B 1 88  ? 43.764  0.533   62.659  1.00 36.00  ?  87  LEU   A HA   1 
ATOM   6233  H  HB2  . LEU   B 1 88  ? 42.776  -0.903  64.155  1.00 41.36  ?  87  LEU   A HB2  1 
ATOM   6234  H  HB3  . LEU   B 1 88  ? 43.806  -0.474  65.287  1.00 41.36  ?  87  LEU   A HB3  1 
ATOM   6235  H  HG   . LEU   B 1 88  ? 42.832  1.697   65.228  1.00 48.14  ?  87  LEU   A HG   1 
ATOM   6236  H  HD11 . LEU   B 1 88  ? 40.853  2.141   64.242  1.00 45.89  ?  87  LEU   A HD11 1 
ATOM   6237  H  HD12 . LEU   B 1 88  ? 41.844  1.611   63.119  1.00 45.89  ?  87  LEU   A HD12 1 
ATOM   6238  H  HD13 . LEU   B 1 88  ? 40.728  0.648   63.712  1.00 45.89  ?  87  LEU   A HD13 1 
ATOM   6239  H  HD21 . LEU   B 1 88  ? 40.896  1.033   66.504  1.00 48.60  ?  87  LEU   A HD21 1 
ATOM   6240  H  HD22 . LEU   B 1 88  ? 41.168  -0.466  66.051  1.00 48.60  ?  87  LEU   A HD22 1 
ATOM   6241  H  HD23 . LEU   B 1 88  ? 42.215  0.286   66.980  1.00 48.60  ?  87  LEU   A HD23 1 
ATOM   6242  N  N    . ASN   B 1 89  ? 46.153  1.341   64.583  1.00 31.18  ?  88  ASN   A N    1 
ATOM   6243  C  CA   . ASN   B 1 89  ? 46.995  2.461   65.008  1.00 37.27  ?  88  ASN   A CA   1 
ATOM   6244  C  C    . ASN   B 1 89  ? 47.402  3.351   63.840  1.00 34.15  ?  88  ASN   A C    1 
ATOM   6245  O  O    . ASN   B 1 89  ? 47.530  4.567   64.003  1.00 29.90  ?  88  ASN   A O    1 
ATOM   6246  C  CB   . ASN   B 1 89  ? 48.215  1.885   65.720  1.00 44.83  ?  88  ASN   A CB   1 
ATOM   6247  C  CG   . ASN   B 1 89  ? 48.900  2.874   66.630  1.00 46.38  ?  88  ASN   A CG   1 
ATOM   6248  O  OD1  . ASN   B 1 89  ? 48.307  3.831   67.136  1.00 45.08  ?  88  ASN   A OD1  1 
ATOM   6249  N  ND2  . ASN   B 1 89  ? 50.166  2.616   66.872  1.00 40.99  ?  88  ASN   A ND2  1 
ATOM   6250  H  H    . ASN   B 1 89  ? 46.466  0.570   64.799  1.00 37.41  ?  88  ASN   A H    1 
ATOM   6251  H  HA   . ASN   B 1 89  ? 46.509  3.032   65.624  1.00 44.73  ?  88  ASN   A HA   1 
ATOM   6252  H  HB2  . ASN   B 1 89  ? 47.935  1.130   66.260  1.00 53.79  ?  88  ASN   A HB2  1 
ATOM   6253  H  HB3  . ASN   B 1 89  ? 48.859  1.598   65.055  1.00 53.79  ?  88  ASN   A HB3  1 
ATOM   6254  H  HD21 . ASN   B 1 89  ? 50.540  1.926   66.520  1.00 49.18  ?  88  ASN   A HD21 1 
ATOM   6255  H  HD22 . ASN   B 1 89  ? 50.621  3.138   67.383  1.00 49.18  ?  88  ASN   A HD22 1 
ATOM   6256  N  N    . HIS   B 1 90  ? 47.562  2.776   62.648  1.00 40.79  ?  89  HIS   A N    1 
ATOM   6257  C  CA   . HIS   B 1 90  ? 47.842  3.566   61.447  1.00 36.84  ?  89  HIS   A CA   1 
ATOM   6258  C  C    . HIS   B 1 90  ? 46.562  4.031   60.752  1.00 34.72  ?  89  HIS   A C    1 
ATOM   6259  O  O    . HIS   B 1 90  ? 46.420  5.212   60.408  1.00 34.06  ?  89  HIS   A O    1 
ATOM   6260  C  CB   . HIS   B 1 90  ? 48.708  2.756   60.481  1.00 42.02  ?  89  HIS   A CB   1 
ATOM   6261  C  CG   . HIS   B 1 90  ? 50.087  2.480   61.009  1.00 47.34  ?  89  HIS   A CG   1 
ATOM   6262  N  ND1  . HIS   B 1 90  ? 50.438  1.269   61.573  1.00 48.29  ?  89  HIS   A ND1  1 
ATOM   6263  C  CD2  . HIS   B 1 90  ? 51.181  3.271   61.105  1.00 44.72  ?  89  HIS   A CD2  1 
ATOM   6264  C  CE1  . HIS   B 1 90  ? 51.700  1.313   61.960  1.00 42.59  ?  89  HIS   A CE1  1 
ATOM   6265  N  NE2  . HIS   B 1 90  ? 52.169  2.522   61.702  1.00 47.04  ?  89  HIS   A NE2  1 
ATOM   6266  H  H    . HIS   B 1 90  ? 47.513  1.929   62.507  1.00 48.94  ?  89  HIS   A H    1 
ATOM   6267  H  HA   . HIS   B 1 90  ? 48.341  4.357   61.705  1.00 44.21  ?  89  HIS   A HA   1 
ATOM   6268  H  HB2  . HIS   B 1 90  ? 48.277  1.903   60.313  1.00 50.42  ?  89  HIS   A HB2  1 
ATOM   6269  H  HB3  . HIS   B 1 90  ? 48.800  3.250   59.651  1.00 50.42  ?  89  HIS   A HB3  1 
ATOM   6270  H  HD1  . HIS   B 1 90  ? 49.916  0.591   61.658  1.00 57.94  ?  89  HIS   A HD1  1 
ATOM   6271  H  HD2  . HIS   B 1 90  ? 51.252  4.154   60.821  1.00 53.66  ?  89  HIS   A HD2  1 
ATOM   6272  H  HE1  . HIS   B 1 90  ? 52.176  0.615   62.347  1.00 51.11  ?  89  HIS   A HE1  1 
ATOM   6273  N  N    . THR   B 1 91  ? 45.585  3.138   60.575  1.00 33.15  ?  90  THR   A N    1 
ATOM   6274  C  CA   . THR   B 1 91  ? 44.440  3.512   59.740  1.00 34.93  ?  90  THR   A CA   1 
ATOM   6275  C  C    . THR   B 1 91  ? 43.519  4.525   60.407  1.00 30.00  ?  90  THR   A C    1 
ATOM   6276  O  O    . THR   B 1 91  ? 42.725  5.168   59.715  1.00 30.34  ?  90  THR   A O    1 
ATOM   6277  C  CB   . THR   B 1 91  ? 43.587  2.308   59.378  1.00 37.57  ?  90  THR   A CB   1 
ATOM   6278  O  OG1  . THR   B 1 91  ? 42.910  1.896   60.549  1.00 30.29  ?  90  THR   A OG1  1 
ATOM   6279  C  CG2  . THR   B 1 91  ? 44.455  1.158   58.866  1.00 37.07  ?  90  THR   A CG2  1 
ATOM   6280  H  H    . THR   B 1 91  ? 45.562  2.347   60.911  1.00 39.78  ?  90  THR   A H    1 
ATOM   6281  H  HA   . THR   B 1 91  ? 44.814  3.890   58.929  1.00 41.92  ?  90  THR   A HA   1 
ATOM   6282  H  HB   . THR   B 1 91  ? 42.959  2.536   58.675  1.00 45.08  ?  90  THR   A HB   1 
ATOM   6283  H  HG1  . THR   B 1 91  ? 42.313  1.338   60.355  1.00 36.35  ?  90  THR   A HG1  1 
ATOM   6284  H  HG21 . THR   B 1 91  ? 43.902  0.499   58.418  1.00 44.48  ?  90  THR   A HG21 1 
ATOM   6285  H  HG22 . THR   B 1 91  ? 45.115  1.494   58.240  1.00 44.48  ?  90  THR   A HG22 1 
ATOM   6286  H  HG23 . THR   B 1 91  ? 44.913  0.733   59.608  1.00 44.48  ?  90  THR   A HG23 1 
ATOM   6287  N  N    . LYS   B 1 92  ? 43.630  4.709   61.726  1.00 31.18  ?  91  LYS   A N    1 
ATOM   6288  C  CA   . LYS   B 1 92  ? 42.921  5.814   62.372  1.00 36.36  ?  91  LYS   A CA   1 
ATOM   6289  C  C    . LYS   B 1 92  ? 43.504  7.163   61.998  1.00 35.54  ?  91  LYS   A C    1 
ATOM   6290  O  O    . LYS   B 1 92  ? 42.860  8.186   62.274  1.00 37.44  ?  91  LYS   A O    1 
ATOM   6291  C  CB   . LYS   B 1 92  ? 42.932  5.680   63.903  1.00 35.49  ?  91  LYS   A CB   1 
ATOM   6292  C  CG   . LYS   B 1 92  ? 44.294  5.898   64.536  1.00 34.70  ?  91  LYS   A CG   1 
ATOM   6293  C  CD   . LYS   B 1 92  ? 44.253  5.482   65.996  1.00 42.15  ?  91  LYS   A CD   1 
ATOM   6294  C  CE   . LYS   B 1 92  ? 45.368  6.161   66.821  1.00 48.69  ?  91  LYS   A CE   1 
ATOM   6295  N  NZ   . LYS   B 1 92  ? 45.794  5.262   67.952  1.00 47.63  ?  91  LYS   A NZ   1 
ATOM   6296  H  H    . LYS   B 1 92  ? 44.098  4.219   62.256  1.00 37.42  ?  91  LYS   A H    1 
ATOM   6297  H  HA   . LYS   B 1 92  ? 41.995  5.771   62.087  1.00 43.63  ?  91  LYS   A HA   1 
ATOM   6298  H  HB2  . LYS   B 1 92  ? 42.325  6.338   64.276  1.00 42.59  ?  91  LYS   A HB2  1 
ATOM   6299  H  HB3  . LYS   B 1 92  ? 42.638  4.786   64.138  1.00 42.59  ?  91  LYS   A HB3  1 
ATOM   6300  H  HG2  . LYS   B 1 92  ? 44.958  5.361   64.077  1.00 41.64  ?  91  LYS   A HG2  1 
ATOM   6301  H  HG3  . LYS   B 1 92  ? 44.532  6.837   64.485  1.00 41.64  ?  91  LYS   A HG3  1 
ATOM   6302  H  HD2  . LYS   B 1 92  ? 43.397  5.735   66.377  1.00 50.58  ?  91  LYS   A HD2  1 
ATOM   6303  H  HD3  . LYS   B 1 92  ? 44.372  4.521   66.058  1.00 50.58  ?  91  LYS   A HD3  1 
ATOM   6304  H  HE2  . LYS   B 1 92  ? 46.136  6.332   66.253  1.00 58.43  ?  91  LYS   A HE2  1 
ATOM   6305  H  HE3  . LYS   B 1 92  ? 45.038  6.994   67.193  1.00 58.43  ?  91  LYS   A HE3  1 
ATOM   6306  H  HZ1  . LYS   B 1 92  ? 46.595  5.509   68.253  1.00 57.16  ?  91  LYS   A HZ1  1 
ATOM   6307  H  HZ2  . LYS   B 1 92  ? 45.207  5.313   68.619  1.00 57.16  ?  91  LYS   A HZ2  1 
ATOM   6308  H  HZ3  . LYS   B 1 92  ? 45.839  4.419   67.671  1.00 57.16  ?  91  LYS   A HZ3  1 
ATOM   6309  N  N    . LYS   B 1 93  ? 44.704  7.193   61.399  1.00 28.90  ?  92  LYS   A N    1 
ATOM   6310  C  CA   . LYS   B 1 93  ? 45.285  8.454   60.979  1.00 33.55  ?  92  LYS   A CA   1 
ATOM   6311  C  C    . LYS   B 1 93  ? 44.982  8.756   59.529  1.00 31.51  ?  92  LYS   A C    1 
ATOM   6312  O  O    . LYS   B 1 93  ? 45.117  9.906   59.105  1.00 36.03  ?  92  LYS   A O    1 
ATOM   6313  C  CB   . LYS   B 1 93  ? 46.811  8.451   61.212  1.00 38.48  ?  92  LYS   A CB   1 
ATOM   6314  C  CG   . LYS   B 1 93  ? 47.186  8.857   62.626  1.00 44.38  ?  92  LYS   A CG   1 
ATOM   6315  C  CD   . LYS   B 1 93  ? 48.588  8.438   63.031  1.00 48.72  ?  92  LYS   A CD   1 
ATOM   6316  C  CE   . LYS   B 1 93  ? 48.612  7.987   64.501  1.00 52.17  ?  92  LYS   A CE   1 
ATOM   6317  N  NZ   . LYS   B 1 93  ? 49.894  7.274   64.864  1.00 64.01  ?  92  LYS   A NZ   1 
ATOM   6318  H  H    . LYS   B 1 93  ? 45.187  6.501   61.231  1.00 34.68  ?  92  LYS   A H    1 
ATOM   6319  H  HA   . LYS   B 1 93  ? 44.924  9.174   61.521  1.00 40.25  ?  92  LYS   A HA   1 
ATOM   6320  H  HB2  . LYS   B 1 93  ? 47.154  7.557   61.055  1.00 46.18  ?  92  LYS   A HB2  1 
ATOM   6321  H  HB3  . LYS   B 1 93  ? 47.226  9.078   60.598  1.00 46.18  ?  92  LYS   A HB3  1 
ATOM   6322  H  HG2  . LYS   B 1 93  ? 47.133  9.823   62.698  1.00 53.25  ?  92  LYS   A HG2  1 
ATOM   6323  H  HG3  . LYS   B 1 93  ? 46.563  8.445   63.245  1.00 53.25  ?  92  LYS   A HG3  1 
ATOM   6324  H  HD2  . LYS   B 1 93  ? 48.880  7.698   62.476  1.00 58.47  ?  92  LYS   A HD2  1 
ATOM   6325  H  HD3  . LYS   B 1 93  ? 49.194  9.189   62.929  1.00 58.47  ?  92  LYS   A HD3  1 
ATOM   6326  H  HE2  . LYS   B 1 93  ? 48.527  8.765   65.074  1.00 62.61  ?  92  LYS   A HE2  1 
ATOM   6327  H  HE3  . LYS   B 1 93  ? 47.874  7.377   64.658  1.00 62.61  ?  92  LYS   A HE3  1 
ATOM   6328  H  HZ1  . LYS   B 1 93  ? 50.575  7.848   64.851  1.00 76.82  ?  92  LYS   A HZ1  1 
ATOM   6329  H  HZ2  . LYS   B 1 93  ? 49.827  6.923   65.679  1.00 76.82  ?  92  LYS   A HZ2  1 
ATOM   6330  H  HZ3  . LYS   B 1 93  ? 50.056  6.622   64.280  1.00 76.82  ?  92  LYS   A HZ3  1 
ATOM   6331  N  N    . TRP   B 1 94  ? 44.568  7.755   58.764  1.00 30.25  ?  93  TRP   A N    1 
ATOM   6332  C  CA   . TRP   B 1 94  ? 44.132  8.008   57.402  1.00 27.12  ?  93  TRP   A CA   1 
ATOM   6333  C  C    . TRP   B 1 94  ? 42.912  8.921   57.380  1.00 35.62  ?  93  TRP   A C    1 
ATOM   6334  O  O    . TRP   B 1 94  ? 42.249  9.139   58.398  1.00 38.57  ?  93  TRP   A O    1 
ATOM   6335  C  CB   . TRP   B 1 94  ? 43.791  6.705   56.684  1.00 28.51  ?  93  TRP   A CB   1 
ATOM   6336  C  CG   . TRP   B 1 94  ? 44.936  5.832   56.453  1.00 31.18  ?  93  TRP   A CG   1 
ATOM   6337  C  CD1  . TRP   B 1 94  ? 46.257  6.134   56.663  1.00 30.93  ?  93  TRP   A CD1  1 
ATOM   6338  C  CD2  . TRP   B 1 94  ? 44.909  4.482   55.982  1.00 33.03  ?  93  TRP   A CD2  1 
ATOM   6339  N  NE1  . TRP   B 1 94  ? 47.039  5.043   56.363  1.00 25.16  ?  93  TRP   A NE1  1 
ATOM   6340  C  CE2  . TRP   B 1 94  ? 46.236  4.020   55.948  1.00 30.54  ?  93  TRP   A CE2  1 
ATOM   6341  C  CE3  . TRP   B 1 94  ? 43.893  3.617   55.594  1.00 33.99  ?  93  TRP   A CE3  1 
ATOM   6342  C  CZ2  . TRP   B 1 94  ? 46.557  2.754   55.529  1.00 31.26  ?  93  TRP   A CZ2  1 
ATOM   6343  C  CZ3  . TRP   B 1 94  ? 44.214  2.360   55.183  1.00 31.43  ?  93  TRP   A CZ3  1 
ATOM   6344  C  CH2  . TRP   B 1 94  ? 45.538  1.939   55.141  1.00 35.32  ?  93  TRP   A CH2  1 
ATOM   6345  H  H    . TRP   B 1 94  ? 44.532  6.931   59.007  1.00 36.30  ?  93  TRP   A H    1 
ATOM   6346  H  HA   . TRP   B 1 94  ? 44.856  8.444   56.926  1.00 32.54  ?  93  TRP   A HA   1 
ATOM   6347  H  HB2  . TRP   B 1 94  ? 43.150  6.213   57.221  1.00 34.22  ?  93  TRP   A HB2  1 
ATOM   6348  H  HB3  . TRP   B 1 94  ? 43.405  6.919   55.820  1.00 34.22  ?  93  TRP   A HB3  1 
ATOM   6349  H  HD1  . TRP   B 1 94  ? 46.577  6.954   56.963  1.00 37.12  ?  93  TRP   A HD1  1 
ATOM   6350  H  HE1  . TRP   B 1 94  ? 47.896  5.010   56.428  1.00 30.19  ?  93  TRP   A HE1  1 
ATOM   6351  H  HE3  . TRP   B 1 94  ? 43.006  3.894   55.615  1.00 40.79  ?  93  TRP   A HE3  1 
ATOM   6352  H  HZ2  . TRP   B 1 94  ? 47.440  2.462   55.510  1.00 37.51  ?  93  TRP   A HZ2  1 
ATOM   6353  H  HZ3  . TRP   B 1 94  ? 43.538  1.775   54.927  1.00 37.72  ?  93  TRP   A HZ3  1 
ATOM   6354  H  HH2  . TRP   B 1 94  ? 45.732  1.080   54.842  1.00 42.38  ?  93  TRP   A HH2  1 
ATOM   6355  N  N    . LYS   B 1 95  ? 42.628  9.449   56.181  1.00 41.75  ?  94  LYS   A N    1 
ATOM   6356  C  CA   . LYS   B 1 95  ? 41.499  10.319  55.893  1.00 29.97  ?  94  LYS   A CA   1 
ATOM   6357  C  C    . LYS   B 1 95  ? 40.588  9.593   54.923  1.00 35.65  ?  94  LYS   A C    1 
ATOM   6358  O  O    . LYS   B 1 95  ? 41.053  8.966   53.957  1.00 36.55  ?  94  LYS   A O    1 
ATOM   6359  C  CB   . LYS   B 1 95  ? 41.902  11.648  55.258  1.00 25.81  ?  94  LYS   A CB   1 
ATOM   6360  C  CG   . LYS   B 1 95  ? 43.111  12.276  55.931  1.00 48.31  ?  94  LYS   A CG   1 
ATOM   6361  C  CD   . LYS   B 1 95  ? 42.659  13.429  56.766  1.00 53.38  ?  94  LYS   A CD   1 
ATOM   6362  C  CE   . LYS   B 1 95  ? 42.572  13.025  58.210  1.00 57.33  ?  94  LYS   A CE   1 
ATOM   6363  N  NZ   . LYS   B 1 95  ? 42.048  14.190  59.004  1.00 84.95  ?  94  LYS   A NZ   1 
ATOM   6364  H  H    . LYS   B 1 95  ? 43.108  9.304   55.483  1.00 50.10  ?  94  LYS   A H    1 
ATOM   6365  H  HA   . LYS   B 1 95  ? 41.048  10.524  56.727  1.00 35.96  ?  94  LYS   A HA   1 
ATOM   6366  H  HB2  . LYS   B 1 95  ? 42.121  11.499  54.325  1.00 30.97  ?  94  LYS   A HB2  1 
ATOM   6367  H  HB3  . LYS   B 1 95  ? 41.161  12.270  55.330  1.00 30.97  ?  94  LYS   A HB3  1 
ATOM   6368  H  HG2  . LYS   B 1 95  ? 43.546  11.624  56.503  1.00 57.97  ?  94  LYS   A HG2  1 
ATOM   6369  H  HG3  . LYS   B 1 95  ? 43.733  12.597  55.260  1.00 57.97  ?  94  LYS   A HG3  1 
ATOM   6370  H  HD2  . LYS   B 1 95  ? 43.295  14.157  56.686  1.00 64.06  ?  94  LYS   A HD2  1 
ATOM   6371  H  HD3  . LYS   B 1 95  ? 41.782  13.720  56.472  1.00 64.06  ?  94  LYS   A HD3  1 
ATOM   6372  H  HE2  . LYS   B 1 95  ? 41.965  12.275  58.309  1.00 68.79  ?  94  LYS   A HE2  1 
ATOM   6373  H  HE3  . LYS   B 1 95  ? 43.451  12.786  58.541  1.00 68.79  ?  94  LYS   A HE3  1 
ATOM   6374  H  HZ1  . LYS   B 1 95  ? 41.989  13.969  59.864  1.00 101.94 ?  94  LYS   A HZ1  1 
ATOM   6375  H  HZ2  . LYS   B 1 95  ? 42.595  14.886  58.921  1.00 101.94 ?  94  LYS   A HZ2  1 
ATOM   6376  H  HZ3  . LYS   B 1 95  ? 41.240  14.421  58.709  1.00 101.94 ?  94  LYS   A HZ3  1 
ATOM   6377  N  N    . TYR   B 1 96  ? 39.290  9.764   55.145  1.00 27.67  ?  95  TYR   A N    1 
ATOM   6378  C  CA   . TYR   B 1 96  ? 38.251  8.981   54.493  1.00 32.43  ?  95  TYR   A CA   1 
ATOM   6379  C  C    . TYR   B 1 96  ? 37.272  9.933   53.857  1.00 25.82  ?  95  TYR   A C    1 
ATOM   6380  O  O    . TYR   B 1 96  ? 36.119  10.000  54.253  1.00 36.12  ?  95  TYR   A O    1 
ATOM   6381  C  CB   . TYR   B 1 96  ? 37.585  8.081   55.514  1.00 24.36  ?  95  TYR   A CB   1 
ATOM   6382  C  CG   . TYR   B 1 96  ? 38.563  7.139   56.117  1.00 32.79  ?  95  TYR   A CG   1 
ATOM   6383  C  CD1  . TYR   B 1 96  ? 38.989  6.023   55.409  1.00 33.27  ?  95  TYR   A CD1  1 
ATOM   6384  C  CD2  . TYR   B 1 96  ? 39.060  7.339   57.401  1.00 32.66  ?  95  TYR   A CD2  1 
ATOM   6385  C  CE1  . TYR   B 1 96  ? 39.857  5.125   55.954  1.00 29.59  ?  95  TYR   A CE1  1 
ATOM   6386  C  CE2  . TYR   B 1 96  ? 39.938  6.407   57.972  1.00 33.81  ?  95  TYR   A CE2  1 
ATOM   6387  C  CZ   . TYR   B 1 96  ? 40.347  5.316   57.215  1.00 34.81  ?  95  TYR   A CZ   1 
ATOM   6388  O  OH   . TYR   B 1 96  ? 41.245  4.370   57.690  1.00 42.42  ?  95  TYR   A OH   1 
ATOM   6389  H  H    . TYR   B 1 96  ? 38.976  10.350  55.691  1.00 33.21  ?  95  TYR   A H    1 
ATOM   6390  H  HA   . TYR   B 1 96  ? 38.623  8.428   53.788  1.00 38.92  ?  95  TYR   A HA   1 
ATOM   6391  H  HB2  . TYR   B 1 96  ? 37.204  8.623   56.222  1.00 29.23  ?  95  TYR   A HB2  1 
ATOM   6392  H  HB3  . TYR   B 1 96  ? 36.888  7.564   55.080  1.00 29.23  ?  95  TYR   A HB3  1 
ATOM   6393  H  HD1  . TYR   B 1 96  ? 38.675  5.885   54.544  1.00 39.93  ?  95  TYR   A HD1  1 
ATOM   6394  H  HD2  . TYR   B 1 96  ? 38.809  8.094   57.882  1.00 39.19  ?  95  TYR   A HD2  1 
ATOM   6395  H  HE1  . TYR   B 1 96  ? 40.117  4.378   55.465  1.00 35.50  ?  95  TYR   A HE1  1 
ATOM   6396  H  HE2  . TYR   B 1 96  ? 40.241  6.518   58.844  1.00 40.58  ?  95  TYR   A HE2  1 
ATOM   6397  H  HH   . TYR   B 1 96  ? 41.419  4.519   58.498  1.00 50.91  ?  95  TYR   A HH   1 
ATOM   6398  N  N    . PRO   B 1 97  ? 37.705  10.689  52.862  1.00 38.41  ?  96  PRO   A N    1 
ATOM   6399  C  CA   . PRO   B 1 97  ? 36.783  11.618  52.196  1.00 30.46  ?  96  PRO   A CA   1 
ATOM   6400  C  C    . PRO   B 1 97  ? 35.654  10.884  51.468  1.00 36.96  ?  96  PRO   A C    1 
ATOM   6401  O  O    . PRO   B 1 97  ? 35.848  9.804   50.889  1.00 34.07  ?  96  PRO   A O    1 
ATOM   6402  C  CB   . PRO   B 1 97  ? 37.696  12.371  51.206  1.00 32.59  ?  96  PRO   A CB   1 
ATOM   6403  C  CG   . PRO   B 1 97  ? 38.874  11.412  50.925  1.00 25.99  ?  96  PRO   A CG   1 
ATOM   6404  C  CD   . PRO   B 1 97  ? 39.066  10.712  52.270  1.00 27.56  ?  96  PRO   A CD   1 
ATOM   6405  H  HA   . PRO   B 1 97  ? 36.401  12.235  52.839  1.00 36.55  ?  96  PRO   A HA   1 
ATOM   6406  H  HB2  . PRO   B 1 97  ? 37.207  12.565  50.391  1.00 39.11  ?  96  PRO   A HB2  1 
ATOM   6407  H  HB3  . PRO   B 1 97  ? 38.009  13.195  51.610  1.00 39.11  ?  96  PRO   A HB3  1 
ATOM   6408  H  HG2  . PRO   B 1 97  ? 38.640  10.781  50.227  1.00 31.19  ?  96  PRO   A HG2  1 
ATOM   6409  H  HG3  . PRO   B 1 97  ? 39.665  11.912  50.670  1.00 31.19  ?  96  PRO   A HG3  1 
ATOM   6410  H  HD2  . PRO   B 1 97  ? 39.399  9.810   52.142  1.00 33.08  ?  96  PRO   A HD2  1 
ATOM   6411  H  HD3  . PRO   B 1 97  ? 39.676  11.214  52.834  1.00 33.08  ?  96  PRO   A HD3  1 
ATOM   6412  N  N    . GLN   B 1 98  ? 34.459  11.470  51.542  1.00 33.55  ?  97  GLN   A N    1 
ATOM   6413  C  CA   . GLN   B 1 98  ? 33.397  11.143  50.602  1.00 38.75  ?  97  GLN   A CA   1 
ATOM   6414  C  C    . GLN   B 1 98  ? 33.818  11.707  49.244  1.00 28.81  ?  97  GLN   A C    1 
ATOM   6415  O  O    . GLN   B 1 98  ? 34.288  12.836  49.140  1.00 34.25  ?  97  GLN   A O    1 
ATOM   6416  C  CB   . GLN   B 1 98  ? 32.061  11.764  51.020  1.00 29.02  ?  97  GLN   A CB   1 
ATOM   6417  C  CG   . GLN   B 1 98  ? 31.142  11.142  52.186  1.00 44.46  ?  97  GLN   A CG   1 
ATOM   6418  C  CD   . GLN   B 1 98  ? 31.002  9.611   52.281  1.00 50.91  ?  97  GLN   A CD   1 
ATOM   6419  O  OE1  . GLN   B 1 98  ? 31.852  8.964   52.864  1.00 46.38  ?  97  GLN   A OE1  1 
ATOM   6420  N  NE2  . GLN   B 1 98  ? 29.837  9.054   51.829  1.00 54.37  ?  97  GLN   A NE2  1 
ATOM   6421  H  H    . GLN   B 1 98  ? 34.241  12.060  52.129  1.00 40.26  ?  97  GLN   A H    1 
ATOM   6422  H  HA   . GLN   B 1 98  ? 33.256  10.184  50.563  1.00 46.50  ?  97  GLN   A HA   1 
ATOM   6423  H  HB2  . GLN   B 1 98  ? 32.254  12.672  51.301  1.00 34.82  ?  97  GLN   A HB2  1 
ATOM   6424  H  HB3  . GLN   B 1 98  ? 31.501  11.774  50.229  1.00 34.82  ?  97  GLN   A HB3  1 
ATOM   6425  H  HG2  . GLN   B 1 98  ? 31.507  11.437  53.035  1.00 53.35  ?  97  GLN   A HG2  1 
ATOM   6426  H  HG3  . GLN   B 1 98  ? 30.245  11.493  52.071  1.00 53.35  ?  97  GLN   A HG3  1 
ATOM   6427  H  HE21 . GLN   B 1 98  ? 29.217  9.556   51.507  1.00 65.24  ?  97  GLN   A HE21 1 
ATOM   6428  H  HE22 . GLN   B 1 98  ? 29.725  8.202   51.866  1.00 65.24  ?  97  GLN   A HE22 1 
ATOM   6429  N  N    . VAL   B 1 99  ? 33.672  10.922  48.201  1.00 35.81  ?  98  VAL   A N    1 
ATOM   6430  C  CA   . VAL   B 1 99  ? 34.080  11.301  46.846  1.00 29.12  ?  98  VAL   A CA   1 
ATOM   6431  C  C    . VAL   B 1 99  ? 33.039  10.661  45.950  1.00 32.41  ?  98  VAL   A C    1 
ATOM   6432  O  O    . VAL   B 1 99  ? 32.826  9.449   46.018  1.00 32.85  ?  98  VAL   A O    1 
ATOM   6433  C  CB   . VAL   B 1 99  ? 35.496  10.804  46.514  1.00 31.02  ?  98  VAL   A CB   1 
ATOM   6434  C  CG1  . VAL   B 1 99  ? 35.843  11.048  45.060  1.00 31.58  ?  98  VAL   A CG1  1 
ATOM   6435  C  CG2  . VAL   B 1 99  ? 36.478  11.500  47.427  1.00 31.81  ?  98  VAL   A CG2  1 
ATOM   6436  H  H    . VAL   B 1 99  ? 33.328  10.135  48.242  1.00 42.98  ?  98  VAL   A H    1 
ATOM   6437  H  HA   . VAL   B 1 99  ? 34.104  12.263  46.729  1.00 34.95  ?  98  VAL   A HA   1 
ATOM   6438  H  HB   . VAL   B 1 99  ? 35.546  9.846   46.655  1.00 37.22  ?  98  VAL   A HB   1 
ATOM   6439  H  HG11 . VAL   B 1 99  ? 36.808  11.076  44.966  1.00 37.89  ?  98  VAL   A HG11 1 
ATOM   6440  H  HG12 . VAL   B 1 99  ? 35.480  10.326  44.524  1.00 37.89  ?  98  VAL   A HG12 1 
ATOM   6441  H  HG13 . VAL   B 1 99  ? 35.459  11.894  44.781  1.00 37.89  ?  98  VAL   A HG13 1 
ATOM   6442  H  HG21 . VAL   B 1 99  ? 37.380  11.267  47.157  1.00 38.17  ?  98  VAL   A HG21 1 
ATOM   6443  H  HG22 . VAL   B 1 99  ? 36.349  12.459  47.357  1.00 38.17  ?  98  VAL   A HG22 1 
ATOM   6444  H  HG23 . VAL   B 1 99  ? 36.320  11.211  48.339  1.00 38.17  ?  98  VAL   A HG23 1 
ATOM   6445  N  N    . ASN   B 1 100 ? 32.370  11.451  45.122  1.00 38.77  ?  99  ASN   A N    1 
ATOM   6446  C  CA   . ASN   B 1 100 ? 31.323  10.927  44.242  1.00 38.61  ?  99  ASN   A CA   1 
ATOM   6447  C  C    . ASN   B 1 100 ? 30.313  10.056  45.006  1.00 39.66  ?  99  ASN   A C    1 
ATOM   6448  O  O    . ASN   B 1 100 ? 29.857  9.011   44.520  1.00 34.63  ?  99  ASN   A O    1 
ATOM   6449  C  CB   . ASN   B 1 100 ? 31.952  10.144  43.087  1.00 42.37  ?  99  ASN   A CB   1 
ATOM   6450  C  CG   . ASN   B 1 100 ? 30.932  9.747   42.026  1.00 44.61  ?  99  ASN   A CG   1 
ATOM   6451  O  OD1  . ASN   B 1 100 ? 30.088  10.532  41.678  1.00 40.22  ?  99  ASN   A OD1  1 
ATOM   6452  N  ND2  . ASN   B 1 100 ? 31.022  8.519   41.522  1.00 39.38  ?  99  ASN   A ND2  1 
ATOM   6453  H  H    . ASN   B 1 100 ? 32.501  12.298  45.047  1.00 46.53  ?  99  ASN   A H    1 
ATOM   6454  H  HA   . ASN   B 1 100 ? 30.824  11.676  43.881  1.00 46.33  ?  99  ASN   A HA   1 
ATOM   6455  H  HB2  . ASN   B 1 100 ? 32.628  10.695  42.663  1.00 50.84  ?  99  ASN   A HB2  1 
ATOM   6456  H  HB3  . ASN   B 1 100 ? 32.355  9.334   43.436  1.00 50.84  ?  99  ASN   A HB3  1 
ATOM   6457  H  HD21 . ASN   B 1 100 ? 31.638  7.986   41.797  1.00 47.25  ?  99  ASN   A HD21 1 
ATOM   6458  H  HD22 . ASN   B 1 100 ? 30.464  8.259   40.922  1.00 47.25  ?  99  ASN   A HD22 1 
ATOM   6459  N  N    . GLY   B 1 101 ? 29.975  10.487  46.223  1.00 34.11  ?  100 GLY   A N    1 
ATOM   6460  C  CA   . GLY   B 1 101 ? 28.973  9.827   47.033  1.00 35.73  ?  100 GLY   A CA   1 
ATOM   6461  C  C    . GLY   B 1 101 ? 29.419  8.559   47.713  1.00 37.48  ?  100 GLY   A C    1 
ATOM   6462  O  O    . GLY   B 1 101 ? 28.572  7.795   48.201  1.00 32.06  ?  100 GLY   A O    1 
ATOM   6463  H  H    . GLY   B 1 101 ? 30.324  11.174  46.604  1.00 40.94  ?  100 GLY   A H    1 
ATOM   6464  H  HA2  . GLY   B 1 101 ? 28.681  10.442  47.723  1.00 42.88  ?  100 GLY   A HA2  1 
ATOM   6465  H  HA3  . GLY   B 1 101 ? 28.217  9.605   46.467  1.00 42.88  ?  100 GLY   A HA3  1 
ATOM   6466  N  N    . LEU   B 1 102 ? 30.727  8.316   47.773  1.00 36.52  ?  101 LEU   A N    1 
ATOM   6467  C  CA   . LEU   B 1 102 ? 31.288  7.081   48.298  1.00 35.13  ?  101 LEU   A CA   1 
ATOM   6468  C  C    . LEU   B 1 102 ? 32.378  7.407   49.305  1.00 32.65  ?  101 LEU   A C    1 
ATOM   6469  O  O    . LEU   B 1 102 ? 33.050  8.438   49.207  1.00 32.54  ?  101 LEU   A O    1 
ATOM   6470  C  CB   . LEU   B 1 102 ? 31.872  6.218   47.158  1.00 30.44  ?  101 LEU   A CB   1 
ATOM   6471  C  CG   . LEU   B 1 102 ? 30.807  5.817   46.146  1.00 31.16  ?  101 LEU   A CG   1 
ATOM   6472  C  CD1  . LEU   B 1 102 ? 31.296  5.173   44.924  1.00 28.54  ?  101 LEU   A CD1  1 
ATOM   6473  C  CD2  . LEU   B 1 102 ? 29.807  4.849   46.851  1.00 40.57  ?  101 LEU   A CD2  1 
ATOM   6474  H  H    . LEU   B 1 102 ? 31.327  8.872   47.506  1.00 43.82  ?  101 LEU   A H    1 
ATOM   6475  H  HA   . LEU   B 1 102 ? 30.600  6.571   48.753  1.00 42.16  ?  101 LEU   A HA   1 
ATOM   6476  H  HB2  . LEU   B 1 102 ? 32.558  6.724   46.695  1.00 36.52  ?  101 LEU   A HB2  1 
ATOM   6477  H  HB3  . LEU   B 1 102 ? 32.253  5.410   47.535  1.00 36.52  ?  101 LEU   A HB3  1 
ATOM   6478  H  HG   . LEU   B 1 102 ? 30.394  6.641   45.845  1.00 37.39  ?  101 LEU   A HG   1 
ATOM   6479  H  HD11 . LEU   B 1 102 ? 30.547  5.020   44.326  1.00 34.25  ?  101 LEU   A HD11 1 
ATOM   6480  H  HD12 . LEU   B 1 102 ? 31.945  5.755   44.498  1.00 34.25  ?  101 LEU   A HD12 1 
ATOM   6481  H  HD13 . LEU   B 1 102 ? 31.711  4.328   45.156  1.00 34.25  ?  101 LEU   A HD13 1 
ATOM   6482  H  HD21 . LEU   B 1 102 ? 29.424  4.253   46.188  1.00 48.69  ?  101 LEU   A HD21 1 
ATOM   6483  H  HD22 . LEU   B 1 102 ? 30.283  4.336   47.522  1.00 48.69  ?  101 LEU   A HD22 1 
ATOM   6484  H  HD23 . LEU   B 1 102 ? 29.105  5.371   47.270  1.00 48.69  ?  101 LEU   A HD23 1 
ATOM   6485  N  N    . THR   B 1 103 ? 32.555  6.529   50.279  1.00 32.30  ?  102 THR   A N    1 
ATOM   6486  C  CA   . THR   B 1 103 ? 33.686  6.668   51.182  1.00 31.46  ?  102 THR   A CA   1 
ATOM   6487  C  C    . THR   B 1 103 ? 34.938  6.180   50.456  1.00 31.79  ?  102 THR   A C    1 
ATOM   6488  O  O    . THR   B 1 103 ? 35.018  5.009   50.086  1.00 27.98  ?  102 THR   A O    1 
ATOM   6489  C  CB   . THR   B 1 103 ? 33.488  5.862   52.460  1.00 36.45  ?  102 THR   A CB   1 
ATOM   6490  O  OG1  . THR   B 1 103 ? 32.273  6.216   53.132  1.00 34.76  ?  102 THR   A OG1  1 
ATOM   6491  C  CG2  . THR   B 1 103 ? 34.679  6.118   53.419  1.00 37.56  ?  102 THR   A CG2  1 
ATOM   6492  H  H    . THR   B 1 103 ? 32.044  5.855   50.435  1.00 38.76  ?  102 THR   A H    1 
ATOM   6493  H  HA   . THR   B 1 103 ? 33.778  7.601   51.434  1.00 37.75  ?  102 THR   A HA   1 
ATOM   6494  H  HB   . THR   B 1 103 ? 33.438  4.922   52.226  1.00 43.74  ?  102 THR   A HB   1 
ATOM   6495  H  HG1  . THR   B 1 103 ? 32.315  7.010   53.402  1.00 41.71  ?  102 THR   A HG1  1 
ATOM   6496  H  HG21 . THR   B 1 103 ? 34.402  5.975   54.338  1.00 45.07  ?  102 THR   A HG21 1 
ATOM   6497  H  HG22 . THR   B 1 103 ? 35.408  5.513   53.212  1.00 45.07  ?  102 THR   A HG22 1 
ATOM   6498  H  HG23 . THR   B 1 103 ? 34.991  7.032   53.324  1.00 45.07  ?  102 THR   A HG23 1 
ATOM   6499  N  N    . SER   B 1 104 ? 35.896  7.056   50.236  1.00 27.01  ?  103 SER   A N    1 
ATOM   6500  C  CA   . SER   B 1 104 ? 37.197  6.664   49.707  1.00 25.33  ?  103 SER   A CA   1 
ATOM   6501  C  C    . SER   B 1 104 ? 38.252  6.788   50.813  1.00 28.97  ?  103 SER   A C    1 
ATOM   6502  O  O    . SER   B 1 104 ? 37.909  6.926   51.998  1.00 33.03  ?  103 SER   A O    1 
ATOM   6503  C  CB   . SER   B 1 104 ? 37.542  7.523   48.489  1.00 27.87  ?  103 SER   A CB   1 
ATOM   6504  O  OG   . SER   B 1 104 ? 38.650  6.988   47.809  1.00 33.08  ?  103 SER   A OG   1 
ATOM   6505  H  H    . SER   B 1 104 ? 35.820  7.900   50.386  1.00 32.41  ?  103 SER   A H    1 
ATOM   6506  H  HA   . SER   B 1 104 ? 37.159  5.738   49.422  1.00 30.39  ?  103 SER   A HA   1 
ATOM   6507  H  HB2  . SER   B 1 104 ? 36.780  7.542   47.889  1.00 33.45  ?  103 SER   A HB2  1 
ATOM   6508  H  HB3  . SER   B 1 104 ? 37.754  8.422   48.785  1.00 33.45  ?  103 SER   A HB3  1 
ATOM   6509  H  HG   . SER   B 1 104 ? 38.730  7.354   47.057  1.00 39.69  ?  103 SER   A HG   1 
ATOM   6510  N  N    . ILE   B 1 105 ? 39.538  6.724   50.424  1.00 27.53  ?  104 ILE   A N    1 
ATOM   6511  C  CA   . ILE   B 1 105 ? 40.660  6.919   51.337  1.00 27.93  ?  104 ILE   A CA   1 
ATOM   6512  C  C    . ILE   B 1 105 ? 41.689  7.798   50.645  1.00 29.42  ?  104 ILE   A C    1 
ATOM   6513  O  O    . ILE   B 1 105 ? 42.077  7.515   49.507  1.00 30.97  ?  104 ILE   A O    1 
ATOM   6514  C  CB   . ILE   B 1 105 ? 41.353  5.608   51.768  1.00 34.21  ?  104 ILE   A CB   1 
ATOM   6515  C  CG1  . ILE   B 1 105 ? 40.350  4.499   52.015  1.00 26.45  ?  104 ILE   A CG1  1 
ATOM   6516  C  CG2  . ILE   B 1 105 ? 42.257  5.837   53.056  1.00 29.23  ?  104 ILE   A CG2  1 
ATOM   6517  C  CD1  . ILE   B 1 105 ? 40.952  3.088   52.245  1.00 21.81  ?  104 ILE   A CD1  1 
ATOM   6518  H  H    . ILE   B 1 105 ? 39.783  6.564   49.616  1.00 33.04  ?  104 ILE   A H    1 
ATOM   6519  H  HA   . ILE   B 1 105 ? 40.312  7.356   52.129  1.00 33.52  ?  104 ILE   A HA   1 
ATOM   6520  H  HB   . ILE   B 1 105 ? 41.924  5.334   51.034  1.00 41.06  ?  104 ILE   A HB   1 
ATOM   6521  H  HG12 . ILE   B 1 105 ? 39.835  4.724   52.805  1.00 31.74  ?  104 ILE   A HG12 1 
ATOM   6522  H  HG13 . ILE   B 1 105 ? 39.766  4.440   51.243  1.00 31.74  ?  104 ILE   A HG13 1 
ATOM   6523  H  HG21 . ILE   B 1 105 ? 42.765  5.030   53.232  1.00 35.08  ?  104 ILE   A HG21 1 
ATOM   6524  H  HG22 . ILE   B 1 105 ? 42.860  6.578   52.891  1.00 35.08  ?  104 ILE   A HG22 1 
ATOM   6525  H  HG23 . ILE   B 1 105 ? 41.684  6.039   53.812  1.00 35.08  ?  104 ILE   A HG23 1 
ATOM   6526  H  HD11 . ILE   B 1 105 ? 40.237  2.471   52.465  1.00 26.17  ?  104 ILE   A HD11 1 
ATOM   6527  H  HD12 . ILE   B 1 105 ? 41.400  2.800   51.434  1.00 26.17  ?  104 ILE   A HD12 1 
ATOM   6528  H  HD13 . ILE   B 1 105 ? 41.588  3.132   52.976  1.00 26.17  ?  104 ILE   A HD13 1 
ATOM   6529  N  N    . LYS   B 1 106 ? 42.166  8.844   51.333  1.00 31.88  ?  105 LYS   A N    1 
ATOM   6530  C  CA   . LYS   B 1 106 ? 43.324  9.578   50.820  1.00 33.25  ?  105 LYS   A CA   1 
ATOM   6531  C  C    . LYS   B 1 106 ? 44.561  8.675   50.791  1.00 30.85  ?  105 LYS   A C    1 
ATOM   6532  O  O    . LYS   B 1 106 ? 44.776  7.844   51.679  1.00 23.99  ?  105 LYS   A O    1 
ATOM   6533  C  CB   . LYS   B 1 106 ? 43.612  10.809  51.658  1.00 37.22  ?  105 LYS   A CB   1 
ATOM   6534  C  CG   . LYS   B 1 106 ? 44.539  11.789  51.006  1.00 25.74  ?  105 LYS   A CG   1 
ATOM   6535  C  CD   . LYS   B 1 106 ? 44.678  13.027  51.879  1.00 28.99  ?  105 LYS   A CD   1 
ATOM   6536  C  CE   . LYS   B 1 106 ? 45.987  13.734  51.570  1.00 37.26  ?  105 LYS   A CE   1 
ATOM   6537  N  NZ   . LYS   B 1 106 ? 46.317  14.682  52.657  1.00 48.07  ?  105 LYS   A NZ   1 
ATOM   6538  H  H    . LYS   B 1 106 ? 41.847  9.137   52.075  1.00 38.26  ?  105 LYS   A H    1 
ATOM   6539  H  HA   . LYS   B 1 106 ? 43.126  9.874   49.917  1.00 39.90  ?  105 LYS   A HA   1 
ATOM   6540  H  HB2  . LYS   B 1 106 ? 42.775  11.267  51.835  1.00 44.66  ?  105 LYS   A HB2  1 
ATOM   6541  H  HB3  . LYS   B 1 106 ? 44.019  10.528  52.493  1.00 44.66  ?  105 LYS   A HB3  1 
ATOM   6542  H  HG2  . LYS   B 1 106 ? 45.414  11.386  50.893  1.00 30.88  ?  105 LYS   A HG2  1 
ATOM   6543  H  HG3  . LYS   B 1 106 ? 44.182  12.053  50.144  1.00 30.88  ?  105 LYS   A HG3  1 
ATOM   6544  H  HD2  . LYS   B 1 106 ? 43.945  13.636  51.702  1.00 34.79  ?  105 LYS   A HD2  1 
ATOM   6545  H  HD3  . LYS   B 1 106 ? 44.676  12.769  52.815  1.00 34.79  ?  105 LYS   A HD3  1 
ATOM   6546  H  HE2  . LYS   B 1 106 ? 46.702  13.083  51.497  1.00 44.71  ?  105 LYS   A HE2  1 
ATOM   6547  H  HE3  . LYS   B 1 106 ? 45.903  14.229  50.740  1.00 44.71  ?  105 LYS   A HE3  1 
ATOM   6548  H  HZ1  . LYS   B 1 106 ? 47.125  15.030  52.523  1.00 57.68  ?  105 LYS   A HZ1  1 
ATOM   6549  H  HZ2  . LYS   B 1 106 ? 45.719  15.341  52.679  1.00 57.68  ?  105 LYS   A HZ2  1 
ATOM   6550  H  HZ3  . LYS   B 1 106 ? 46.310  14.260  53.441  1.00 57.68  ?  105 LYS   A HZ3  1 
ATOM   6551  N  N    . TRP   B 1 107 ? 45.371  8.822   49.750  1.00 29.71  ?  106 TRP   A N    1 
ATOM   6552  C  CA   . TRP   B 1 107 ? 46.489  7.902   49.559  1.00 26.08  ?  106 TRP   A CA   1 
ATOM   6553  C  C    . TRP   B 1 107 ? 47.445  7.974   50.735  1.00 28.57  ?  106 TRP   A C    1 
ATOM   6554  O  O    . TRP   B 1 107 ? 47.794  9.058   51.217  1.00 28.70  ?  106 TRP   A O    1 
ATOM   6555  C  CB   . TRP   B 1 107 ? 47.270  8.202   48.268  1.00 24.04  ?  106 TRP   A CB   1 
ATOM   6556  C  CG   . TRP   B 1 107 ? 48.252  7.127   48.001  1.00 23.88  ?  106 TRP   A CG   1 
ATOM   6557  C  CD1  . TRP   B 1 107 ? 48.004  5.968   47.352  1.00 27.56  ?  106 TRP   A CD1  1 
ATOM   6558  C  CD2  . TRP   B 1 107 ? 49.638  7.065   48.419  1.00 27.41  ?  106 TRP   A CD2  1 
ATOM   6559  N  NE1  . TRP   B 1 107 ? 49.152  5.214   47.275  1.00 32.56  ?  106 TRP   A NE1  1 
ATOM   6560  C  CE2  . TRP   B 1 107 ? 50.164  5.856   47.937  1.00 29.30  ?  106 TRP   A CE2  1 
ATOM   6561  C  CE3  . TRP   B 1 107 ? 50.482  7.925   49.132  1.00 33.21  ?  106 TRP   A CE3  1 
ATOM   6562  C  CZ2  . TRP   B 1 107 ? 51.491  5.467   48.149  1.00 29.98  ?  106 TRP   A CZ2  1 
ATOM   6563  C  CZ3  . TRP   B 1 107 ? 51.826  7.536   49.369  1.00 22.63  ?  106 TRP   A CZ3  1 
ATOM   6564  C  CH2  . TRP   B 1 107 ? 52.304  6.318   48.888  1.00 25.80  ?  106 TRP   A CH2  1 
ATOM   6565  H  H    . TRP   B 1 107 ? 45.298  9.434   49.150  1.00 35.65  ?  106 TRP   A H    1 
ATOM   6566  H  HA   . TRP   B 1 107 ? 46.122  7.007   49.485  1.00 31.29  ?  106 TRP   A HA   1 
ATOM   6567  H  HB2  . TRP   B 1 107 ? 46.655  8.253   47.520  1.00 28.85  ?  106 TRP   A HB2  1 
ATOM   6568  H  HB3  . TRP   B 1 107 ? 47.747  9.041   48.363  1.00 28.85  ?  106 TRP   A HB3  1 
ATOM   6569  H  HD1  . TRP   B 1 107 ? 47.178  5.716   47.007  1.00 33.07  ?  106 TRP   A HD1  1 
ATOM   6570  H  HE1  . TRP   B 1 107 ? 49.223  4.457   46.873  1.00 39.08  ?  106 TRP   A HE1  1 
ATOM   6571  H  HE3  . TRP   B 1 107 ? 50.166  8.741   49.447  1.00 39.85  ?  106 TRP   A HE3  1 
ATOM   6572  H  HZ2  . TRP   B 1 107 ? 51.818  4.666   47.808  1.00 35.98  ?  106 TRP   A HZ2  1 
ATOM   6573  H  HZ3  . TRP   B 1 107 ? 52.392  8.097   49.848  1.00 27.16  ?  106 TRP   A HZ3  1 
ATOM   6574  H  HH2  . TRP   B 1 107 ? 53.183  6.071   49.064  1.00 30.96  ?  106 TRP   A HH2  1 
ATOM   6575  N  N    . ALA   B 1 108 ? 47.902  6.808   51.177  1.00 32.14  ?  107 ALA   A N    1 
ATOM   6576  C  CA   . ALA   B 1 108 ? 48.967  6.719   52.157  1.00 31.05  ?  107 ALA   A CA   1 
ATOM   6577  C  C    . ALA   B 1 108 ? 49.365  5.269   52.257  1.00 28.68  ?  107 ALA   A C    1 
ATOM   6578  O  O    . ALA   B 1 108 ? 48.550  4.378   52.028  1.00 25.31  ?  107 ALA   A O    1 
ATOM   6579  C  CB   . ALA   B 1 108 ? 48.528  7.267   53.516  1.00 31.51  ?  107 ALA   A CB   1 
ATOM   6580  H  H    . ALA   B 1 108 ? 47.604  6.043   50.919  1.00 38.57  ?  107 ALA   A H    1 
ATOM   6581  H  HA   . ALA   B 1 108 ? 49.738  7.236   51.874  1.00 37.26  ?  107 ALA   A HA   1 
ATOM   6582  H  HB1  . ALA   B 1 108 ? 49.197  7.038   54.180  1.00 37.81  ?  107 ALA   A HB1  1 
ATOM   6583  H  HB2  . ALA   B 1 108 ? 48.441  8.232   53.454  1.00 37.81  ?  107 ALA   A HB2  1 
ATOM   6584  H  HB3  . ALA   B 1 108 ? 47.675  6.873   53.755  1.00 37.81  ?  107 ALA   A HB3  1 
ATOM   6585  N  N    . ASP   B 1 109 ? 50.641  5.045   52.551  1.00 29.62  ?  108 ASP   A N    1 
ATOM   6586  C  CA   . ASP   B 1 109 ? 51.131  3.707   52.893  1.00 28.83  ?  108 ASP   A CA   1 
ATOM   6587  C  C    . ASP   B 1 109 ? 50.641  2.655   51.883  1.00 31.24  ?  108 ASP   A C    1 
ATOM   6588  O  O    . ASP   B 1 109 ? 50.216  1.549   52.247  1.00 31.29  ?  108 ASP   A O    1 
ATOM   6589  C  CB   . ASP   B 1 109 ? 50.699  3.317   54.323  1.00 31.32  ?  108 ASP   A CB   1 
ATOM   6590  C  CG   . ASP   B 1 109 ? 50.852  4.452   55.340  1.00 44.04  ?  108 ASP   A CG   1 
ATOM   6591  O  OD1  . ASP   B 1 109 ? 51.928  5.052   55.394  1.00 38.10  ?  108 ASP   A OD1  1 
ATOM   6592  O  OD2  . ASP   B 1 109 ? 49.897  4.771   56.131  1.00 40.26  ?  108 ASP   A OD2  1 
ATOM   6593  H  H    . ASP   B 1 109 ? 51.249  5.653   52.560  1.00 35.55  ?  108 ASP   A H    1 
ATOM   6594  H  HA   . ASP   B 1 109 ? 52.100  3.724   52.855  1.00 34.59  ?  108 ASP   A HA   1 
ATOM   6595  H  HB2  . ASP   B 1 109 ? 49.765  3.056   54.308  1.00 37.58  ?  108 ASP   A HB2  1 
ATOM   6596  H  HB3  . ASP   B 1 109 ? 51.247  2.574   54.623  1.00 37.58  ?  108 ASP   A HB3  1 
ATOM   6597  N  N    . ASN   B 1 110 ? 50.693  3.005   50.594  1.00 29.65  ?  109 ASN   A N    1 
ATOM   6598  C  CA   . ASN   B 1 110 ? 50.313  2.087   49.527  1.00 29.94  ?  109 ASN   A CA   1 
ATOM   6599  C  C    . ASN   B 1 110 ? 48.880  1.573   49.671  1.00 31.44  ?  109 ASN   A C    1 
ATOM   6600  O  O    . ASN   B 1 110 ? 48.598  0.401   49.378  1.00 21.34  ?  109 ASN   A O    1 
ATOM   6601  C  CB   . ASN   B 1 110 ? 51.232  0.871   49.487  1.00 29.71  ?  109 ASN   A CB   1 
ATOM   6602  C  CG   . ASN   B 1 110 ? 52.525  1.151   48.797  1.00 39.60  ?  109 ASN   A CG   1 
ATOM   6603  O  OD1  . ASN   B 1 110 ? 52.644  2.131   48.059  1.00 44.16  ?  109 ASN   A OD1  1 
ATOM   6604  N  ND2  . ASN   B 1 110 ? 53.500  0.299   49.023  1.00 37.19  ?  109 ASN   A ND2  1 
ATOM   6605  H  H    . ASN   B 1 110 ? 50.949  3.777   50.314  1.00 35.58  ?  109 ASN   A H    1 
ATOM   6606  H  HA   . ASN   B 1 110 ? 50.383  2.589   48.699  1.00 35.92  ?  109 ASN   A HA   1 
ATOM   6607  H  HB2  . ASN   B 1 110 ? 51.430  0.594   50.396  1.00 35.65  ?  109 ASN   A HB2  1 
ATOM   6608  H  HB3  . ASN   B 1 110 ? 50.786  0.153   49.011  1.00 35.65  ?  109 ASN   A HB3  1 
ATOM   6609  H  HD21 . ASN   B 1 110 ? 53.371  -0.373  49.544  1.00 44.63  ?  109 ASN   A HD21 1 
ATOM   6610  H  HD22 . ASN   B 1 110 ? 54.266  0.413   48.650  1.00 44.63  ?  109 ASN   A HD22 1 
ATOM   6611  N  N    . ASN   B 1 111 ? 47.965  2.398   50.161  1.00 26.73  ?  110 ASN   A N    1 
ATOM   6612  C  CA   . ASN   B 1 111 ? 46.620  1.919   50.441  1.00 30.24  ?  110 ASN   A CA   1 
ATOM   6613  C  C    . ASN   B 1 111 ? 45.686  2.065   49.252  1.00 33.14  ?  110 ASN   A C    1 
ATOM   6614  O  O    . ASN   B 1 111 ? 44.457  2.128   49.427  1.00 29.85  ?  110 ASN   A O    1 
ATOM   6615  C  CB   . ASN   B 1 111 ? 46.062  2.640   51.660  1.00 25.30  ?  110 ASN   A CB   1 
ATOM   6616  C  CG   . ASN   B 1 111 ? 45.739  4.065   51.386  1.00 27.37  ?  110 ASN   A CG   1 
ATOM   6617  O  OD1  . ASN   B 1 111 ? 45.842  4.525   50.268  1.00 26.35  ?  110 ASN   A OD1  1 
ATOM   6618  N  ND2  . ASN   B 1 111 ? 45.349  4.799   52.442  1.00 27.56  ?  110 ASN   A ND2  1 
ATOM   6619  H  H    . ASN   B 1 111 ? 48.098  3.229   50.337  1.00 32.07  ?  110 ASN   A H    1 
ATOM   6620  H  HA   . ASN   B 1 111 ? 46.664  0.974   50.653  1.00 36.28  ?  110 ASN   A HA   1 
ATOM   6621  H  HB2  . ASN   B 1 111 ? 45.247  2.196   51.944  1.00 30.36  ?  110 ASN   A HB2  1 
ATOM   6622  H  HB3  . ASN   B 1 111 ? 46.720  2.613   52.372  1.00 30.36  ?  110 ASN   A HB3  1 
ATOM   6623  H  HD21 . ASN   B 1 111 ? 45.150  5.630   52.340  1.00 33.07  ?  110 ASN   A HD21 1 
ATOM   6624  H  HD22 . ASN   B 1 111 ? 45.298  4.438   53.221  1.00 33.07  ?  110 ASN   A HD22 1 
ATOM   6625  N  N    . SER   B 1 112 ? 46.225  2.168   48.034  1.00 24.79  ?  111 SER   A N    1 
ATOM   6626  C  CA   . SER   B 1 112 ? 45.303  2.346   46.923  1.00 26.86  ?  111 SER   A CA   1 
ATOM   6627  C  C    . SER   B 1 112 ? 44.454  1.080   46.658  1.00 29.75  ?  111 SER   A C    1 
ATOM   6628  O  O    . SER   B 1 112 ? 43.345  1.167   46.093  1.00 28.06  ?  111 SER   A O    1 
ATOM   6629  C  CB   . SER   B 1 112 ? 46.065  2.720   45.674  1.00 24.63  ?  111 SER   A CB   1 
ATOM   6630  O  OG   . SER   B 1 112 ? 46.716  1.561   45.154  1.00 25.37  ?  111 SER   A OG   1 
ATOM   6631  H  H    . SER   B 1 112 ? 47.063  2.139   47.842  1.00 29.75  ?  111 SER   A H    1 
ATOM   6632  H  HA   . SER   B 1 112 ? 44.697  3.070   47.145  1.00 32.24  ?  111 SER   A HA   1 
ATOM   6633  H  HB2  . SER   B 1 112 ? 45.448  3.067   45.011  1.00 29.56  ?  111 SER   A HB2  1 
ATOM   6634  H  HB3  . SER   B 1 112 ? 46.730  3.392   45.891  1.00 29.56  ?  111 SER   A HB3  1 
ATOM   6635  H  HG   . SER   B 1 112 ? 46.155  1.061   44.779  1.00 30.45  ?  111 SER   A HG   1 
ATOM   6636  N  N    . TYR   B 1 113 ? 44.998  -0.109  46.974  1.00 28.02  ?  112 TYR   A N    1 
ATOM   6637  C  CA   . TYR   B 1 113 ? 44.227  -1.309  46.713  1.00 22.47  ?  112 TYR   A CA   1 
ATOM   6638  C  C    . TYR   B 1 113 ? 43.020  -1.371  47.622  1.00 31.19  ?  112 TYR   A C    1 
ATOM   6639  O  O    . TYR   B 1 113 ? 41.977  -1.906  47.204  1.00 24.90  ?  112 TYR   A O    1 
ATOM   6640  C  CB   . TYR   B 1 113 ? 45.018  -2.579  46.899  1.00 22.02  ?  112 TYR   A CB   1 
ATOM   6641  C  CG   . TYR   B 1 113 ? 45.396  -2.956  48.297  1.00 21.98  ?  112 TYR   A CG   1 
ATOM   6642  C  CD1  . TYR   B 1 113 ? 46.317  -2.207  49.007  1.00 21.73  ?  112 TYR   A CD1  1 
ATOM   6643  C  CD2  . TYR   B 1 113 ? 44.921  -4.126  48.880  1.00 27.50  ?  112 TYR   A CD2  1 
ATOM   6644  C  CE1  . TYR   B 1 113 ? 46.695  -2.553  50.257  1.00 26.07  ?  112 TYR   A CE1  1 
ATOM   6645  C  CE2  . TYR   B 1 113 ? 45.393  -4.530  50.169  1.00 23.73  ?  112 TYR   A CE2  1 
ATOM   6646  C  CZ   . TYR   B 1 113 ? 46.244  -3.699  50.836  1.00 23.78  ?  112 TYR   A CZ   1 
ATOM   6647  O  OH   . TYR   B 1 113 ? 46.694  -3.982  52.105  1.00 31.61  ?  112 TYR   A OH   1 
ATOM   6648  H  H    . TYR   B 1 113 ? 45.774  -0.230  47.323  1.00 33.63  ?  112 TYR   A H    1 
ATOM   6649  H  HA   . TYR   B 1 113 ? 43.967  -1.274  45.779  1.00 26.97  ?  112 TYR   A HA   1 
ATOM   6650  H  HB2  . TYR   B 1 113 ? 44.492  -3.312  46.544  1.00 26.42  ?  112 TYR   A HB2  1 
ATOM   6651  H  HB3  . TYR   B 1 113 ? 45.845  -2.491  46.399  1.00 26.42  ?  112 TYR   A HB3  1 
ATOM   6652  H  HD1  . TYR   B 1 113 ? 46.684  -1.448  48.615  1.00 26.07  ?  112 TYR   A HD1  1 
ATOM   6653  H  HD2  . TYR   B 1 113 ? 44.295  -4.646  48.431  1.00 33.00  ?  112 TYR   A HD2  1 
ATOM   6654  H  HE1  . TYR   B 1 113 ? 47.274  -1.999  50.729  1.00 31.28  ?  112 TYR   A HE1  1 
ATOM   6655  H  HE2  . TYR   B 1 113 ? 45.126  -5.339  50.543  1.00 28.48  ?  112 TYR   A HE2  1 
ATOM   6656  H  HH   . TYR   B 1 113 ? 46.529  -4.784  52.296  1.00 37.93  ?  112 TYR   A HH   1 
ATOM   6657  N  N    . LEU   B 1 114 ? 43.158  -0.822  48.844  1.00 27.13  ?  113 LEU   A N    1 
ATOM   6658  C  CA   . LEU   B 1 114 ? 42.087  -0.815  49.827  1.00 28.72  ?  113 LEU   A CA   1 
ATOM   6659  C  C    . LEU   B 1 114 ? 41.018  0.177   49.413  1.00 32.27  ?  113 LEU   A C    1 
ATOM   6660  O  O    . LEU   B 1 114 ? 39.831  -0.172  49.319  1.00 27.33  ?  113 LEU   A O    1 
ATOM   6661  C  CB   . LEU   B 1 114 ? 42.671  -0.473  51.198  1.00 31.68  ?  113 LEU   A CB   1 
ATOM   6662  C  CG   . LEU   B 1 114 ? 43.520  -1.570  51.858  1.00 32.87  ?  113 LEU   A CG   1 
ATOM   6663  C  CD1  . LEU   B 1 114 ? 44.323  -1.062  53.061  1.00 35.47  ?  113 LEU   A CD1  1 
ATOM   6664  C  CD2  . LEU   B 1 114 ? 42.625  -2.712  52.255  1.00 34.94  ?  113 LEU   A CD2  1 
ATOM   6665  H  H    . LEU   B 1 114 ? 43.877  -0.443  49.124  1.00 32.55  ?  113 LEU   A H    1 
ATOM   6666  H  HA   . LEU   B 1 114 ? 41.675  -1.691  49.892  1.00 34.47  ?  113 LEU   A HA   1 
ATOM   6667  H  HB2  . LEU   B 1 114 ? 43.237  0.309   51.099  1.00 38.02  ?  113 LEU   A HB2  1 
ATOM   6668  H  HB3  . LEU   B 1 114 ? 41.936  -0.276  51.799  1.00 38.02  ?  113 LEU   A HB3  1 
ATOM   6669  H  HG   . LEU   B 1 114 ? 44.179  -1.878  51.216  1.00 39.45  ?  113 LEU   A HG   1 
ATOM   6670  H  HD11 . LEU   B 1 114 ? 44.986  -1.728  53.302  1.00 42.56  ?  113 LEU   A HD11 1 
ATOM   6671  H  HD12 . LEU   B 1 114 ? 44.761  -0.231  52.820  1.00 42.56  ?  113 LEU   A HD12 1 
ATOM   6672  H  HD13 . LEU   B 1 114 ? 43.718  -0.914  53.804  1.00 42.56  ?  113 LEU   A HD13 1 
ATOM   6673  H  HD21 . LEU   B 1 114 ? 43.065  -3.234  52.945  1.00 41.93  ?  113 LEU   A HD21 1 
ATOM   6674  H  HD22 . LEU   B 1 114 ? 41.789  -2.355  52.593  1.00 41.93  ?  113 LEU   A HD22 1 
ATOM   6675  H  HD23 . LEU   B 1 114 ? 42.457  -3.267  51.477  1.00 41.93  ?  113 LEU   A HD23 1 
ATOM   6676  N  N    . ALA   B 1 115 ? 41.434  1.421   49.138  1.00 27.10  ?  114 ALA   A N    1 
ATOM   6677  C  CA   . ALA   B 1 115 ? 40.514  2.368   48.535  1.00 32.02  ?  114 ALA   A CA   1 
ATOM   6678  C  C    . ALA   B 1 115 ? 39.680  1.642   47.487  1.00 31.63  ?  114 ALA   A C    1 
ATOM   6679  O  O    . ALA   B 1 115 ? 38.489  1.488   47.675  1.00 28.22  ?  114 ALA   A O    1 
ATOM   6680  C  CB   . ALA   B 1 115 ? 41.239  3.556   47.939  1.00 28.56  ?  114 ALA   A CB   1 
ATOM   6681  H  H    . ALA   B 1 115 ? 42.224  1.724   49.290  1.00 32.52  ?  114 ALA   A H    1 
ATOM   6682  H  HA   . ALA   B 1 115 ? 39.936  2.741   49.220  1.00 38.42  ?  114 ALA   A HA   1 
ATOM   6683  H  HB1  . ALA   B 1 115 ? 40.588  4.159   47.547  1.00 34.28  ?  114 ALA   A HB1  1 
ATOM   6684  H  HB2  . ALA   B 1 115 ? 41.730  4.011   48.640  1.00 34.28  ?  114 ALA   A HB2  1 
ATOM   6685  H  HB3  . ALA   B 1 115 ? 41.851  3.241   47.256  1.00 34.28  ?  114 ALA   A HB3  1 
ATOM   6686  N  N    . THR   B 1 116 ? 40.312  1.003   46.498  1.00 31.92  ?  115 THR   A N    1 
ATOM   6687  C  CA   . THR   B 1 116 ? 39.574  0.392   45.387  1.00 27.22  ?  115 THR   A CA   1 
ATOM   6688  C  C    . THR   B 1 116 ? 38.618  -0.682  45.871  1.00 28.58  ?  115 THR   A C    1 
ATOM   6689  O  O    . THR   B 1 116 ? 37.481  -0.758  45.382  1.00 27.25  ?  115 THR   A O    1 
ATOM   6690  C  CB   . THR   B 1 116 ? 40.563  -0.170  44.355  1.00 34.35  ?  115 THR   A CB   1 
ATOM   6691  O  OG1  . THR   B 1 116 ? 41.316  0.910   43.803  1.00 35.43  ?  115 THR   A OG1  1 
ATOM   6692  C  CG2  . THR   B 1 116 ? 39.793  -0.845  43.271  1.00 33.06  ?  115 THR   A CG2  1 
ATOM   6693  H  H    . THR   B 1 116 ? 41.165  0.908   46.446  1.00 38.31  ?  115 THR   A H    1 
ATOM   6694  H  HA   . THR   B 1 116 ? 39.040  1.075   44.952  1.00 32.66  ?  115 THR   A HA   1 
ATOM   6695  H  HB   . THR   B 1 116 ? 41.169  -0.809  44.761  1.00 41.22  ?  115 THR   A HB   1 
ATOM   6696  H  HG1  . THR   B 1 116 ? 41.629  0.690   43.055  1.00 42.52  ?  115 THR   A HG1  1 
ATOM   6697  H  HG21 . THR   B 1 116 ? 40.397  -1.157  42.579  1.00 39.67  ?  115 THR   A HG21 1 
ATOM   6698  H  HG22 . THR   B 1 116 ? 39.309  -1.604  43.631  1.00 39.67  ?  115 THR   A HG22 1 
ATOM   6699  H  HG23 . THR   B 1 116 ? 39.159  -0.225  42.878  1.00 39.67  ?  115 THR   A HG23 1 
ATOM   6700  N  N    . ALA   B 1 117 ? 39.052  -1.522  46.814  1.00 23.35  ?  116 ALA   A N    1 
ATOM   6701  C  CA   . ALA   B 1 117 ? 38.133  -2.503  47.393  1.00 28.19  ?  116 ALA   A CA   1 
ATOM   6702  C  C    . ALA   B 1 117 ? 36.948  -1.827  48.105  1.00 28.19  ?  116 ALA   A C    1 
ATOM   6703  O  O    . ALA   B 1 117 ? 35.780  -2.233  47.953  1.00 32.30  ?  116 ALA   A O    1 
ATOM   6704  C  CB   . ALA   B 1 117 ? 38.910  -3.409  48.347  1.00 28.45  ?  116 ALA   A CB   1 
ATOM   6705  H  H    . ALA   B 1 117 ? 39.852  -1.543  47.128  1.00 28.02  ?  116 ALA   A H    1 
ATOM   6706  H  HA   . ALA   B 1 117 ? 37.760  -3.048  46.683  1.00 33.83  ?  116 ALA   A HA   1 
ATOM   6707  H  HB1  . ALA   B 1 117 ? 38.287  -3.995  48.805  1.00 34.14  ?  116 ALA   A HB1  1 
ATOM   6708  H  HB2  . ALA   B 1 117 ? 39.545  -3.936  47.836  1.00 34.14  ?  116 ALA   A HB2  1 
ATOM   6709  H  HB3  . ALA   B 1 117 ? 39.381  -2.859  48.992  1.00 34.14  ?  116 ALA   A HB3  1 
ATOM   6710  N  N    . LEU   B 1 118 ? 37.227  -0.781  48.880  1.00 28.77  ?  117 LEU   A N    1 
ATOM   6711  C  CA   . LEU   B 1 118 ? 36.176  -0.124  49.659  1.00 34.83  ?  117 LEU   A CA   1 
ATOM   6712  C  C    . LEU   B 1 118 ? 35.156  0.557   48.752  1.00 29.32  ?  117 LEU   A C    1 
ATOM   6713  O  O    . LEU   B 1 118 ? 33.947  0.454   48.985  1.00 29.16  ?  117 LEU   A O    1 
ATOM   6714  C  CB   . LEU   B 1 118 ? 36.790  0.875   50.644  1.00 29.48  ?  117 LEU   A CB   1 
ATOM   6715  C  CG   . LEU   B 1 118 ? 35.758  1.601   51.520  1.00 30.29  ?  117 LEU   A CG   1 
ATOM   6716  C  CD1  . LEU   B 1 118 ? 35.028  0.719   52.422  1.00 34.03  ?  117 LEU   A CD1  1 
ATOM   6717  C  CD2  . LEU   B 1 118 ? 36.617  2.623   52.268  1.00 30.30  ?  117 LEU   A CD2  1 
ATOM   6718  H  H    . LEU   B 1 118 ? 38.008  -0.434  48.973  1.00 34.53  ?  117 LEU   A H    1 
ATOM   6719  H  HA   . LEU   B 1 118 ? 35.708  -0.797  50.177  1.00 41.79  ?  117 LEU   A HA   1 
ATOM   6720  H  HB2  . LEU   B 1 118 ? 37.395  0.398   51.233  1.00 35.37  ?  117 LEU   A HB2  1 
ATOM   6721  H  HB3  . LEU   B 1 118 ? 37.277  1.547   50.141  1.00 35.37  ?  117 LEU   A HB3  1 
ATOM   6722  H  HG   . LEU   B 1 118 ? 35.041  2.004   51.006  1.00 36.35  ?  117 LEU   A HG   1 
ATOM   6723  H  HD11 . LEU   B 1 118 ? 34.727  1.231   53.189  1.00 40.83  ?  117 LEU   A HD11 1 
ATOM   6724  H  HD12 . LEU   B 1 118 ? 34.266  0.347   51.952  1.00 40.83  ?  117 LEU   A HD12 1 
ATOM   6725  H  HD13 . LEU   B 1 118 ? 35.618  0.006   52.712  1.00 40.83  ?  117 LEU   A HD13 1 
ATOM   6726  H  HD21 . LEU   B 1 118 ? 36.178  2.856   53.100  1.00 36.36  ?  117 LEU   A HD21 1 
ATOM   6727  H  HD22 . LEU   B 1 118 ? 37.486  2.231   52.451  1.00 36.36  ?  117 LEU   A HD22 1 
ATOM   6728  H  HD23 . LEU   B 1 118 ? 36.721  3.413   51.715  1.00 36.36  ?  117 LEU   A HD23 1 
ATOM   6729  N  N    . LEU   B 1 119 ? 35.611  1.280   47.724  1.00 29.81  ?  118 LEU   A N    1 
ATOM   6730  C  CA   . LEU   B 1 119 ? 34.641  1.793   46.760  1.00 34.67  ?  118 LEU   A CA   1 
ATOM   6731  C  C    . LEU   B 1 119 ? 33.785  0.650   46.203  1.00 30.91  ?  118 LEU   A C    1 
ATOM   6732  O  O    . LEU   B 1 119 ? 32.560  0.778   46.016  1.00 31.42  ?  118 LEU   A O    1 
ATOM   6733  C  CB   . LEU   B 1 119 ? 35.297  2.493   45.571  1.00 35.81  ?  118 LEU   A CB   1 
ATOM   6734  C  CG   . LEU   B 1 119 ? 36.115  3.761   45.645  1.00 37.08  ?  118 LEU   A CG   1 
ATOM   6735  C  CD1  . LEU   B 1 119 ? 35.298  4.855   46.419  1.00 30.78  ?  118 LEU   A CD1  1 
ATOM   6736  C  CD2  . LEU   B 1 119 ? 37.320  3.485   46.295  1.00 43.30  ?  118 LEU   A CD2  1 
ATOM   6737  H  H    . LEU   B 1 119 ? 36.435  1.476   47.572  1.00 35.77  ?  118 LEU   A H    1 
ATOM   6738  H  HA   . LEU   B 1 119 ? 34.104  2.447   47.232  1.00 41.60  ?  118 LEU   A HA   1 
ATOM   6739  H  HB2  . LEU   B 1 119 ? 35.893  1.839   45.174  1.00 42.98  ?  118 LEU   A HB2  1 
ATOM   6740  H  HB3  . LEU   B 1 119 ? 34.576  2.702   44.956  1.00 42.98  ?  118 LEU   A HB3  1 
ATOM   6741  H  HG   . LEU   B 1 119 ? 36.316  4.101   44.759  1.00 44.50  ?  118 LEU   A HG   1 
ATOM   6742  H  HD11 . LEU   B 1 119 ? 35.835  5.660   46.490  1.00 36.93  ?  118 LEU   A HD11 1 
ATOM   6743  H  HD12 . LEU   B 1 119 ? 34.482  5.045   45.930  1.00 36.93  ?  118 LEU   A HD12 1 
ATOM   6744  H  HD13 . LEU   B 1 119 ? 35.083  4.522   47.304  1.00 36.93  ?  118 LEU   A HD13 1 
ATOM   6745  H  HD21 . LEU   B 1 119 ? 37.862  4.289   46.310  1.00 51.96  ?  118 LEU   A HD21 1 
ATOM   6746  H  HD22 . LEU   B 1 119 ? 37.130  3.197   47.202  1.00 51.96  ?  118 LEU   A HD22 1 
ATOM   6747  H  HD23 . LEU   B 1 119 ? 37.784  2.782   45.815  1.00 51.96  ?  118 LEU   A HD23 1 
ATOM   6748  N  N    . THR   B 1 120 ? 34.421  -0.489  45.917  1.00 28.10  ?  119 THR   A N    1 
ATOM   6749  C  CA   . THR   B 1 120 ? 33.706  -1.561  45.232  1.00 36.26  ?  119 THR   A CA   1 
ATOM   6750  C  C    . THR   B 1 120 ? 32.632  -2.166  46.111  1.00 28.16  ?  119 THR   A C    1 
ATOM   6751  O  O    . THR   B 1 120 ? 31.551  -2.506  45.624  1.00 29.73  ?  119 THR   A O    1 
ATOM   6752  C  CB   . THR   B 1 120 ? 34.684  -2.625  44.762  1.00 30.63  ?  119 THR   A CB   1 
ATOM   6753  O  OG1  . THR   B 1 120 ? 35.601  -1.957  43.906  1.00 31.68  ?  119 THR   A OG1  1 
ATOM   6754  C  CG2  . THR   B 1 120 ? 33.953  -3.724  43.957  1.00 30.78  ?  119 THR   A CG2  1 
ATOM   6755  H  H    . THR   B 1 120 ? 35.243  -0.659  46.105  1.00 33.72  ?  119 THR   A H    1 
ATOM   6756  H  HA   . THR   B 1 120 ? 33.270  -1.190  44.449  1.00 43.51  ?  119 THR   A HA   1 
ATOM   6757  H  HB   . THR   B 1 120 ? 35.126  -3.060  45.508  1.00 36.76  ?  119 THR   A HB   1 
ATOM   6758  H  HG1  . THR   B 1 120 ? 35.597  -2.313  43.146  1.00 38.01  ?  119 THR   A HG1  1 
ATOM   6759  H  HG21 . THR   B 1 120 ? 34.600  -4.313  43.538  1.00 36.93  ?  119 THR   A HG21 1 
ATOM   6760  H  HG22 . THR   B 1 120 ? 33.387  -4.246  44.546  1.00 36.93  ?  119 THR   A HG22 1 
ATOM   6761  H  HG23 . THR   B 1 120 ? 33.403  -3.320  43.268  1.00 36.93  ?  119 THR   A HG23 1 
ATOM   6762  N  N    . LEU   B 1 121 ? 32.930  -2.339  47.400  1.00 34.51  ?  120 LEU   A N    1 
ATOM   6763  C  CA   . LEU   B 1 121 ? 31.962  -2.947  48.311  1.00 36.21  ?  120 LEU   A CA   1 
ATOM   6764  C  C    . LEU   B 1 121 ? 30.768  -2.041  48.482  1.00 34.18  ?  120 LEU   A C    1 
ATOM   6765  O  O    . LEU   B 1 121 ? 29.647  -2.522  48.515  1.00 39.90  ?  120 LEU   A O    1 
ATOM   6766  C  CB   . LEU   B 1 121 ? 32.601  -3.296  49.653  1.00 35.90  ?  120 LEU   A CB   1 
ATOM   6767  C  CG   . LEU   B 1 121 ? 33.629  -4.397  49.450  1.00 33.47  ?  120 LEU   A CG   1 
ATOM   6768  C  CD1  . LEU   B 1 121 ? 34.780  -4.127  50.428  1.00 45.41  ?  120 LEU   A CD1  1 
ATOM   6769  C  CD2  . LEU   B 1 121 ? 33.126  -5.790  49.598  1.00 31.46  ?  120 LEU   A CD2  1 
ATOM   6770  H  H    . LEU   B 1 121 ? 33.676  -2.117  47.767  1.00 41.41  ?  120 LEU   A H    1 
ATOM   6771  H  HA   . LEU   B 1 121 ? 31.659  -3.790  47.941  1.00 43.45  ?  120 LEU   A HA   1 
ATOM   6772  H  HB2  . LEU   B 1 121 ? 33.044  -2.514  50.019  1.00 43.09  ?  120 LEU   A HB2  1 
ATOM   6773  H  HB3  . LEU   B 1 121 ? 31.920  -3.610  50.269  1.00 43.09  ?  120 LEU   A HB3  1 
ATOM   6774  H  HG   . LEU   B 1 121 ? 33.917  -4.367  48.524  1.00 40.17  ?  120 LEU   A HG   1 
ATOM   6775  H  HD11 . LEU   B 1 121 ? 35.436  -4.837  50.347  1.00 54.50  ?  120 LEU   A HD11 1 
ATOM   6776  H  HD12 . LEU   B 1 121 ? 35.187  -3.274  50.209  1.00 54.50  ?  120 LEU   A HD12 1 
ATOM   6777  H  HD13 . LEU   B 1 121 ? 34.428  -4.104  51.331  1.00 54.50  ?  120 LEU   A HD13 1 
ATOM   6778  H  HD21 . LEU   B 1 121 ? 33.804  -6.407  49.280  1.00 37.75  ?  120 LEU   A HD21 1 
ATOM   6779  H  HD22 . LEU   B 1 121 ? 32.938  -5.960  50.534  1.00 37.75  ?  120 LEU   A HD22 1 
ATOM   6780  H  HD23 . LEU   B 1 121 ? 32.315  -5.891  49.075  1.00 37.75  ?  120 LEU   A HD23 1 
ATOM   6781  N  N    . GLN   B 1 122 ? 30.959  -0.743  48.437  1.00 38.38  ?  121 GLN   A N    1 
ATOM   6782  C  CA   . GLN   B 1 122 ? 29.807  0.138   48.496  1.00 30.59  ?  121 GLN   A CA   1 
ATOM   6783  C  C    . GLN   B 1 122 ? 28.902  0.056   47.288  1.00 35.41  ?  121 GLN   A C    1 
ATOM   6784  O  O    . GLN   B 1 122 ? 27.837  0.709   47.306  1.00 36.06  ?  121 GLN   A O    1 
ATOM   6785  C  CB   . GLN   B 1 122 ? 30.273  1.574   48.650  1.00 26.13  ?  121 GLN   A CB   1 
ATOM   6786  C  CG   . GLN   B 1 122 ? 30.589  1.897   50.090  1.00 28.72  ?  121 GLN   A CG   1 
ATOM   6787  C  CD   . GLN   B 1 122 ? 31.498  3.032   50.210  1.00 33.04  ?  121 GLN   A CD   1 
ATOM   6788  O  OE1  . GLN   B 1 122 ? 31.058  4.137   50.579  1.00 30.01  ?  121 GLN   A OE1  1 
ATOM   6789  N  NE2  . GLN   B 1 122 ? 32.779  2.815   49.844  1.00 29.15  ?  121 GLN   A NE2  1 
ATOM   6790  H  H    . GLN   B 1 122 ? 31.723  -0.353  48.374  1.00 46.06  ?  121 GLN   A H    1 
ATOM   6791  H  HA   . GLN   B 1 122 ? 29.284  -0.120  49.271  1.00 36.71  ?  121 GLN   A HA   1 
ATOM   6792  H  HB2  . GLN   B 1 122 ? 31.076  1.710   48.122  1.00 31.36  ?  121 GLN   A HB2  1 
ATOM   6793  H  HB3  . GLN   B 1 122 ? 29.573  2.173   48.348  1.00 31.36  ?  121 GLN   A HB3  1 
ATOM   6794  H  HG2  . GLN   B 1 122 ? 29.767  2.117   50.556  1.00 34.46  ?  121 GLN   A HG2  1 
ATOM   6795  H  HG3  . GLN   B 1 122 ? 31.009  1.127   50.505  1.00 34.46  ?  121 GLN   A HG3  1 
ATOM   6796  H  HE21 . GLN   B 1 122 ? 33.020  2.040   49.560  1.00 34.98  ?  121 GLN   A HE21 1 
ATOM   6797  H  HE22 . GLN   B 1 122 ? 33.355  3.452   49.896  1.00 34.98  ?  121 GLN   A HE22 1 
ATOM   6798  N  N    . GLN   B 1 123 ? 29.241  -0.733  46.274  1.00 30.49  ?  122 GLN   A N    1 
ATOM   6799  C  CA   . GLN   B 1 123 ? 28.462  -0.762  45.056  1.00 36.90  ?  122 GLN   A CA   1 
ATOM   6800  C  C    . GLN   B 1 123 ? 27.809  -2.106  44.754  1.00 32.08  ?  122 GLN   A C    1 
ATOM   6801  O  O    . GLN   B 1 123 ? 27.085  -2.212  43.758  1.00 40.97  ?  122 GLN   A O    1 
ATOM   6802  C  CB   . GLN   B 1 123 ? 29.361  -0.336  43.892  1.00 30.64  ?  122 GLN   A CB   1 
ATOM   6803  C  CG   . GLN   B 1 123 ? 29.469  1.158   43.815  1.00 30.76  ?  122 GLN   A CG   1 
ATOM   6804  C  CD   . GLN   B 1 123 ? 30.388  1.636   42.695  1.00 40.35  ?  122 GLN   A CD   1 
ATOM   6805  O  OE1  . GLN   B 1 123 ? 29.936  1.995   41.642  1.00 39.54  ?  122 GLN   A OE1  1 
ATOM   6806  N  NE2  . GLN   B 1 123 ? 31.689  1.606   42.930  1.00 37.93  ?  122 GLN   A NE2  1 
ATOM   6807  H  H    . GLN   B 1 123 ? 29.921  -1.260  46.273  1.00 36.58  ?  122 GLN   A H    1 
ATOM   6808  H  HA   . GLN   B 1 123 ? 27.730  -0.131  45.136  1.00 44.28  ?  122 GLN   A HA   1 
ATOM   6809  H  HB2  . GLN   B 1 123 ? 30.250  -0.702  44.020  1.00 36.77  ?  122 GLN   A HB2  1 
ATOM   6810  H  HB3  . GLN   B 1 123 ? 28.986  -0.661  43.059  1.00 36.77  ?  122 GLN   A HB3  1 
ATOM   6811  H  HG2  . GLN   B 1 123 ? 28.587  1.529   43.655  1.00 36.92  ?  122 GLN   A HG2  1 
ATOM   6812  H  HG3  . GLN   B 1 123 ? 29.822  1.492   44.654  1.00 36.92  ?  122 GLN   A HG3  1 
ATOM   6813  H  HE21 . GLN   B 1 123 ? 31.983  1.326   43.688  1.00 45.52  ?  122 GLN   A HE21 1 
ATOM   6814  H  HE22 . GLN   B 1 123 ? 32.242  1.868   42.325  1.00 45.52  ?  122 GLN   A HE22 1 
ATOM   6815  N  N    . ILE   B 1 124 ? 28.028  -3.123  45.570  1.00 37.23  ?  123 ILE   A N    1 
ATOM   6816  C  CA   . ILE   B 1 124 ? 27.513  -4.452  45.297  1.00 38.54  ?  123 ILE   A CA   1 
ATOM   6817  C  C    . ILE   B 1 124 ? 26.869  -4.994  46.568  1.00 42.51  ?  123 ILE   A C    1 
ATOM   6818  O  O    . ILE   B 1 124 ? 27.164  -4.546  47.684  1.00 35.77  ?  123 ILE   A O    1 
ATOM   6819  C  CB   . ILE   B 1 124 ? 28.627  -5.396  44.810  1.00 41.06  ?  123 ILE   A CB   1 
ATOM   6820  C  CG1  . ILE   B 1 124 ? 29.709  -5.501  45.889  1.00 38.40  ?  123 ILE   A CG1  1 
ATOM   6821  C  CG2  . ILE   B 1 124 ? 29.224  -4.898  43.519  1.00 40.69  ?  123 ILE   A CG2  1 
ATOM   6822  C  CD1  . ILE   B 1 124 ? 30.814  -6.452  45.510  1.00 37.02  ?  123 ILE   A CD1  1 
ATOM   6823  H  H    . ILE   B 1 124 ? 28.480  -3.067  46.299  1.00 44.67  ?  123 ILE   A H    1 
ATOM   6824  H  HA   . ILE   B 1 124 ? 26.827  -4.406  44.613  1.00 46.25  ?  123 ILE   A HA   1 
ATOM   6825  H  HB   . ILE   B 1 124 ? 28.244  -6.273  44.646  1.00 49.27  ?  123 ILE   A HB   1 
ATOM   6826  H  HG12 . ILE   B 1 124 ? 30.101  -4.625  46.030  1.00 46.08  ?  123 ILE   A HG12 1 
ATOM   6827  H  HG13 . ILE   B 1 124 ? 29.306  -5.820  46.711  1.00 46.08  ?  123 ILE   A HG13 1 
ATOM   6828  H  HG21 . ILE   B 1 124 ? 29.728  -5.617  43.106  1.00 48.83  ?  123 ILE   A HG21 1 
ATOM   6829  H  HG22 . ILE   B 1 124 ? 28.509  -4.614  42.929  1.00 48.83  ?  123 ILE   A HG22 1 
ATOM   6830  H  HG23 . ILE   B 1 124 ? 29.811  -4.150  43.711  1.00 48.83  ?  123 ILE   A HG23 1 
ATOM   6831  H  HD11 . ILE   B 1 124 ? 31.307  -6.698  46.308  1.00 44.43  ?  123 ILE   A HD11 1 
ATOM   6832  H  HD12 . ILE   B 1 124 ? 30.424  -7.243  45.105  1.00 44.43  ?  123 ILE   A HD12 1 
ATOM   6833  H  HD13 . ILE   B 1 124 ? 31.405  -6.014  44.878  1.00 44.43  ?  123 ILE   A HD13 1 
ATOM   6834  N  N    . GLU   B 1 125 ? 25.986  -5.983  46.376  1.00 47.93  ?  124 GLU   A N    1 
ATOM   6835  C  CA   . GLU   B 1 125 ? 25.183  -6.523  47.471  1.00 49.59  ?  124 GLU   A CA   1 
ATOM   6836  C  C    . GLU   B 1 125 ? 25.977  -7.594  48.207  1.00 40.01  ?  124 GLU   A C    1 
ATOM   6837  O  O    . GLU   B 1 125 ? 26.066  -8.734  47.743  1.00 37.26  ?  124 GLU   A O    1 
ATOM   6838  C  CB   . GLU   B 1 125 ? 23.886  -7.145  46.966  1.00 48.99  ?  124 GLU   A CB   1 
ATOM   6839  C  CG   . GLU   B 1 125 ? 22.714  -6.257  46.677  1.00 60.37  ?  124 GLU   A CG   1 
ATOM   6840  C  CD   . GLU   B 1 125 ? 21.459  -7.082  46.241  1.00 63.58  ?  124 GLU   A CD   1 
ATOM   6841  O  OE1  . GLU   B 1 125 ? 20.657  -6.557  45.430  1.00 61.45  ?  124 GLU   A OE1  1 
ATOM   6842  O  OE2  . GLU   B 1 125 ? 21.273  -8.249  46.707  1.00 57.29  ?  124 GLU   A OE2  1 
ATOM   6843  H  H    . GLU   B 1 125 ? 25.836  -6.356  45.617  1.00 57.51  ?  124 GLU   A H    1 
ATOM   6844  H  HA   . GLU   B 1 125 ? 24.978  -5.786  48.067  1.00 59.50  ?  124 GLU   A HA   1 
ATOM   6845  H  HB2  . GLU   B 1 125 ? 24.088  -7.608  46.137  1.00 58.79  ?  124 GLU   A HB2  1 
ATOM   6846  H  HB3  . GLU   B 1 125 ? 23.588  -7.781  47.635  1.00 58.79  ?  124 GLU   A HB3  1 
ATOM   6847  H  HG2  . GLU   B 1 125 ? 22.488  -5.755  47.476  1.00 72.45  ?  124 GLU   A HG2  1 
ATOM   6848  H  HG3  . GLU   B 1 125 ? 22.944  -5.648  45.957  1.00 72.45  ?  124 GLU   A HG3  1 
ATOM   6849  N  N    . LEU   B 1 126 ? 26.449  -7.282  49.401  1.00 41.14  ?  125 LEU   A N    1 
ATOM   6850  C  CA   . LEU   B 1 126 ? 27.246  -8.245  50.151  1.00 45.02  ?  125 LEU   A CA   1 
ATOM   6851  C  C    . LEU   B 1 126 ? 26.898  -8.255  51.633  1.00 43.73  ?  125 LEU   A C    1 
ATOM   6852  O  O    . LEU   B 1 126 ? 26.690  -7.202  52.246  1.00 45.70  ?  125 LEU   A O    1 
ATOM   6853  C  CB   . LEU   B 1 126 ? 28.719  -7.938  49.990  1.00 36.80  ?  125 LEU   A CB   1 
ATOM   6854  C  CG   . LEU   B 1 126 ? 29.658  -9.065  50.368  1.00 46.65  ?  125 LEU   A CG   1 
ATOM   6855  C  CD1  . LEU   B 1 126 ? 29.316  -10.265 49.488  1.00 43.70  ?  125 LEU   A CD1  1 
ATOM   6856  C  CD2  . LEU   B 1 126 ? 31.127  -8.676  50.227  1.00 40.31  ?  125 LEU   A CD2  1 
ATOM   6857  H  H    . LEU   B 1 126 ? 26.325  -6.529  49.797  1.00 49.37  ?  125 LEU   A H    1 
ATOM   6858  H  HA   . LEU   B 1 126 ? 27.041  -9.132  49.819  1.00 54.03  ?  125 LEU   A HA   1 
ATOM   6859  H  HB2  . LEU   B 1 126 ? 28.885  -7.721  49.059  1.00 44.16  ?  125 LEU   A HB2  1 
ATOM   6860  H  HB3  . LEU   B 1 126 ? 28.936  -7.178  50.552  1.00 44.16  ?  125 LEU   A HB3  1 
ATOM   6861  H  HG   . LEU   B 1 126 ? 29.543  -9.289  51.304  1.00 55.98  ?  125 LEU   A HG   1 
ATOM   6862  H  HD11 . LEU   B 1 126 ? 30.061  -10.887 49.499  1.00 52.44  ?  125 LEU   A HD11 1 
ATOM   6863  H  HD12 . LEU   B 1 126 ? 28.520  -10.695 49.836  1.00 52.44  ?  125 LEU   A HD12 1 
ATOM   6864  H  HD13 . LEU   B 1 126 ? 29.156  -9.957  48.582  1.00 52.44  ?  125 LEU   A HD13 1 
ATOM   6865  H  HD21 . LEU   B 1 126 ? 31.676  -9.372  50.620  1.00 48.37  ?  125 LEU   A HD21 1 
ATOM   6866  H  HD22 . LEU   B 1 126 ? 31.339  -8.579  49.285  1.00 48.37  ?  125 LEU   A HD22 1 
ATOM   6867  H  HD23 . LEU   B 1 126 ? 31.277  -7.836  50.688  1.00 48.37  ?  125 LEU   A HD23 1 
ATOM   6868  N  N    . LYS   B 1 127 ? 26.864  -9.461  52.194  1.00 38.03  ?  126 LYS   A N    1 
ATOM   6869  C  CA   . LYS   B 1 127 ? 26.412  -9.714  53.559  1.00 43.34  ?  126 LYS   A CA   1 
ATOM   6870  C  C    . LYS   B 1 127 ? 27.533  -10.474 54.256  1.00 38.04  ?  126 LYS   A C    1 
ATOM   6871  O  O    . LYS   B 1 127 ? 27.831  -11.623 53.907  1.00 37.86  ?  126 LYS   A O    1 
ATOM   6872  C  CB   . LYS   B 1 127 ? 25.088  -10.507 53.589  1.00 56.98  ?  126 LYS   A CB   1 
ATOM   6873  C  CG   . LYS   B 1 127 ? 24.924  -11.552 52.427  1.00 66.94  ?  126 LYS   A CG   1 
ATOM   6874  C  CD   . LYS   B 1 127 ? 23.442  -11.982 52.163  1.00 59.01  ?  126 LYS   A CD   1 
ATOM   6875  C  CE   . LYS   B 1 127 ? 22.660  -10.934 51.359  1.00 56.65  ?  126 LYS   A CE   1 
ATOM   6876  N  NZ   . LYS   B 1 127 ? 23.012  -10.946 49.897  1.00 78.02  ?  126 LYS   A NZ   1 
ATOM   6877  H  H    . LYS   B 1 127 ? 27.108  -10.178 51.786  1.00 45.64  ?  126 LYS   A H    1 
ATOM   6878  H  HA   . LYS   B 1 127 ? 26.254  -8.876  54.021  1.00 52.01  ?  126 LYS   A HA   1 
ATOM   6879  H  HB2  . LYS   B 1 127 ? 25.037  -10.991 54.428  1.00 68.38  ?  126 LYS   A HB2  1 
ATOM   6880  H  HB3  . LYS   B 1 127 ? 24.351  -9.879  53.523  1.00 68.38  ?  126 LYS   A HB3  1 
ATOM   6881  H  HG2  . LYS   B 1 127 ? 25.269  -11.164 51.608  1.00 80.33  ?  126 LYS   A HG2  1 
ATOM   6882  H  HG3  . LYS   B 1 127 ? 25.427  -12.350 52.653  1.00 80.33  ?  126 LYS   A HG3  1 
ATOM   6883  H  HD2  . LYS   B 1 127 ? 23.437  -12.812 51.661  1.00 70.82  ?  126 LYS   A HD2  1 
ATOM   6884  H  HD3  . LYS   B 1 127 ? 22.991  -12.106 53.013  1.00 70.82  ?  126 LYS   A HD3  1 
ATOM   6885  H  HE2  . LYS   B 1 127 ? 21.711  -11.115 51.441  1.00 67.98  ?  126 LYS   A HE2  1 
ATOM   6886  H  HE3  . LYS   B 1 127 ? 22.861  -10.051 51.709  1.00 67.98  ?  126 LYS   A HE3  1 
ATOM   6887  H  HZ1  . LYS   B 1 127 ? 22.548  -10.320 49.467  1.00 93.63  ?  126 LYS   A HZ1  1 
ATOM   6888  H  HZ2  . LYS   B 1 127 ? 23.881  -10.785 49.792  1.00 93.63  ?  126 LYS   A HZ2  1 
ATOM   6889  H  HZ3  . LYS   B 1 127 ? 22.821  -11.741 49.545  1.00 93.63  ?  126 LYS   A HZ3  1 
ATOM   6890  N  N    . PHE   B 1 128 ? 28.173  -9.821  55.214  1.00 34.50  ?  127 PHE   A N    1 
ATOM   6891  C  CA   . PHE   B 1 128 ? 29.256  -10.427 55.966  1.00 36.35  ?  127 PHE   A CA   1 
ATOM   6892  C  C    . PHE   B 1 128 ? 28.673  -11.244 57.117  1.00 33.79  ?  127 PHE   A C    1 
ATOM   6893  O  O    . PHE   B 1 128 ? 27.675  -10.872 57.710  1.00 35.45  ?  127 PHE   A O    1 
ATOM   6894  C  CB   . PHE   B 1 128 ? 30.174  -9.332  56.510  1.00 35.21  ?  127 PHE   A CB   1 
ATOM   6895  C  CG   . PHE   B 1 128 ? 31.069  -8.733  55.504  1.00 31.14  ?  127 PHE   A CG   1 
ATOM   6896  C  CD1  . PHE   B 1 128 ? 32.027  -9.515  54.873  1.00 36.40  ?  127 PHE   A CD1  1 
ATOM   6897  C  CD2  . PHE   B 1 128 ? 31.005  -7.403  55.234  1.00 31.79  ?  127 PHE   A CD2  1 
ATOM   6898  C  CE1  . PHE   B 1 128 ? 32.875  -8.987  53.951  1.00 34.32  ?  127 PHE   A CE1  1 
ATOM   6899  C  CE2  . PHE   B 1 128 ? 31.849  -6.849  54.331  1.00 37.93  ?  127 PHE   A CE2  1 
ATOM   6900  C  CZ   . PHE   B 1 128 ? 32.793  -7.641  53.672  1.00 32.47  ?  127 PHE   A CZ   1 
ATOM   6901  H  H    . PHE   B 1 128 ? 27.996  -9.013  55.451  1.00 41.39  ?  127 PHE   A H    1 
ATOM   6902  H  HA   . PHE   B 1 128 ? 29.784  -11.015 55.404  1.00 43.62  ?  127 PHE   A HA   1 
ATOM   6903  H  HB2  . PHE   B 1 128 ? 29.625  -8.621  56.876  1.00 42.25  ?  127 PHE   A HB2  1 
ATOM   6904  H  HB3  . PHE   B 1 128 ? 30.730  -9.713  57.207  1.00 42.25  ?  127 PHE   A HB3  1 
ATOM   6905  H  HD1  . PHE   B 1 128 ? 32.089  -10.418 55.085  1.00 43.68  ?  127 PHE   A HD1  1 
ATOM   6906  H  HD2  . PHE   B 1 128 ? 30.379  -6.871  55.670  1.00 38.15  ?  127 PHE   A HD2  1 
ATOM   6907  H  HE1  . PHE   B 1 128 ? 33.499  -9.524  53.518  1.00 41.18  ?  127 PHE   A HE1  1 
ATOM   6908  H  HE2  . PHE   B 1 128 ? 31.800  -5.938  54.150  1.00 45.52  ?  127 PHE   A HE2  1 
ATOM   6909  H  HZ   . PHE   B 1 128 ? 33.365  -7.259  53.045  1.00 38.97  ?  127 PHE   A HZ   1 
ATOM   6910  N  N    . ASN   B 1 129 ? 29.312  -12.321 57.436  1.00 30.26  ?  128 ASN   A N    1 
ATOM   6911  C  CA   . ASN   B 1 129 ? 28.977  -13.228 58.512  1.00 35.22  ?  128 ASN   A CA   1 
ATOM   6912  C  C    . ASN   B 1 129 ? 29.620  -12.805 59.828  1.00 40.32  ?  128 ASN   A C    1 
ATOM   6913  O  O    . ASN   B 1 129 ? 28.922  -12.779 60.842  1.00 47.37  ?  128 ASN   A O    1 
ATOM   6914  C  CB   . ASN   B 1 129 ? 29.381  -14.644 58.098  1.00 27.87  ?  128 ASN   A CB   1 
ATOM   6915  C  CG   . ASN   B 1 129 ? 28.525  -15.162 56.901  1.00 38.33  ?  128 ASN   A CG   1 
ATOM   6916  O  OD1  . ASN   B 1 129 ? 27.383  -14.746 56.707  1.00 39.28  ?  128 ASN   A OD1  1 
ATOM   6917  N  ND2  . ASN   B 1 129 ? 29.078  -16.068 56.134  1.00 38.76  ?  128 ASN   A ND2  1 
ATOM   6918  H  H    . ASN   B 1 129 ? 30.011  -12.586 57.011  1.00 36.31  ?  128 ASN   A H    1 
ATOM   6919  H  HA   . ASN   B 1 129 ? 28.022  -13.209 58.681  1.00 42.26  ?  128 ASN   A HA   1 
ATOM   6920  H  HB2  . ASN   B 1 129 ? 30.313  -14.645 57.829  1.00 33.45  ?  128 ASN   A HB2  1 
ATOM   6921  H  HB3  . ASN   B 1 129 ? 29.252  -15.246 58.848  1.00 33.45  ?  128 ASN   A HB3  1 
ATOM   6922  H  HD21 . ASN   B 1 129 ? 29.874  -16.347 56.303  1.00 46.51  ?  128 ASN   A HD21 1 
ATOM   6923  H  HD22 . ASN   B 1 129 ? 28.646  -16.384 55.461  1.00 46.51  ?  128 ASN   A HD22 1 
ATOM   6924  N  N    . PRO   B 1 130 ? 30.885  -12.414 59.863  1.00 34.97  ?  129 PRO   A N    1 
ATOM   6925  C  CA   . PRO   B 1 130 ? 31.499  -11.989 61.136  1.00 34.90  ?  129 PRO   A CA   1 
ATOM   6926  C  C    . PRO   B 1 130 ? 30.997  -10.625 61.569  1.00 38.91  ?  129 PRO   A C    1 
ATOM   6927  O  O    . PRO   B 1 130 ? 31.125  -9.640  60.815  1.00 38.24  ?  129 PRO   A O    1 
ATOM   6928  C  CB   . PRO   B 1 130 ? 33.008  -11.938 60.827  1.00 40.80  ?  129 PRO   A CB   1 
ATOM   6929  C  CG   . PRO   B 1 130 ? 33.187  -12.702 59.511  1.00 40.25  ?  129 PRO   A CG   1 
ATOM   6930  C  CD   . PRO   B 1 130 ? 31.861  -12.533 58.760  1.00 36.00  ?  129 PRO   A CD   1 
ATOM   6931  H  HA   . PRO   B 1 130 ? 31.322  -12.647 61.827  1.00 41.88  ?  129 PRO   A HA   1 
ATOM   6932  H  HB2  . PRO   B 1 130 ? 33.291  -11.016 60.731  1.00 48.96  ?  129 PRO   A HB2  1 
ATOM   6933  H  HB3  . PRO   B 1 130 ? 33.503  -12.365 61.543  1.00 48.96  ?  129 PRO   A HB3  1 
ATOM   6934  H  HG2  . PRO   B 1 130 ? 33.921  -12.319 59.006  1.00 48.30  ?  129 PRO   A HG2  1 
ATOM   6935  H  HG3  . PRO   B 1 130 ? 33.362  -13.638 59.695  1.00 48.30  ?  129 PRO   A HG3  1 
ATOM   6936  H  HD2  . PRO   B 1 130 ? 31.869  -11.731 58.214  1.00 43.20  ?  129 PRO   A HD2  1 
ATOM   6937  H  HD3  . PRO   B 1 130 ? 31.671  -13.308 58.208  1.00 43.20  ?  129 PRO   A HD3  1 
ATOM   6938  N  N    . PRO   B 1 131 ? 30.436  -10.529 62.787  1.00 37.06  ?  130 PRO   A N    1 
ATOM   6939  C  CA   . PRO   B 1 131 ? 29.878  -9.240  63.239  1.00 32.31  ?  130 PRO   A CA   1 
ATOM   6940  C  C    . PRO   B 1 131 ? 30.883  -8.098  63.201  1.00 31.93  ?  130 PRO   A C    1 
ATOM   6941  O  O    . PRO   B 1 131 ? 30.520  -6.940  62.938  1.00 31.51  ?  130 PRO   A O    1 
ATOM   6942  C  CB   . PRO   B 1 131 ? 29.401  -9.539  64.672  1.00 31.03  ?  130 PRO   A CB   1 
ATOM   6943  C  CG   . PRO   B 1 131 ? 29.155  -11.012 64.685  1.00 39.12  ?  130 PRO   A CG   1 
ATOM   6944  C  CD   . PRO   B 1 131 ? 30.101  -11.642 63.701  1.00 41.16  ?  130 PRO   A CD   1 
ATOM   6945  H  HA   . PRO   B 1 131 ? 29.111  -9.005  62.694  1.00 38.77  ?  130 PRO   A HA   1 
ATOM   6946  H  HB2  . PRO   B 1 131 ? 30.090  -9.294  65.309  1.00 37.24  ?  130 PRO   A HB2  1 
ATOM   6947  H  HB3  . PRO   B 1 131 ? 28.586  -9.047  64.860  1.00 37.24  ?  130 PRO   A HB3  1 
ATOM   6948  H  HG2  . PRO   B 1 131 ? 29.319  -11.355 65.577  1.00 46.94  ?  130 PRO   A HG2  1 
ATOM   6949  H  HG3  . PRO   B 1 131 ? 28.236  -11.185 64.427  1.00 46.94  ?  130 PRO   A HG3  1 
ATOM   6950  H  HD2  . PRO   B 1 131 ? 30.895  -11.971 64.149  1.00 49.39  ?  130 PRO   A HD2  1 
ATOM   6951  H  HD3  . PRO   B 1 131 ? 29.667  -12.364 63.220  1.00 49.39  ?  130 PRO   A HD3  1 
ATOM   6952  N  N    . ALA   B 1 132 ? 32.150  -8.390  63.437  1.00 33.73  ?  131 ALA   A N    1 
ATOM   6953  C  CA   . ALA   B 1 132 ? 33.162  -7.353  63.315  1.00 31.93  ?  131 ALA   A CA   1 
ATOM   6954  C  C    . ALA   B 1 132 ? 33.115  -6.705  61.935  1.00 28.20  ?  131 ALA   A C    1 
ATOM   6955  O  O    . ALA   B 1 132 ? 33.154  -5.472  61.803  1.00 25.74  ?  131 ALA   A O    1 
ATOM   6956  C  CB   . ALA   B 1 132 ? 34.531  -7.968  63.599  1.00 33.66  ?  131 ALA   A CB   1 
ATOM   6957  H  H    . ALA   B 1 132 ? 32.446  -9.164  63.666  1.00 40.48  ?  131 ALA   A H    1 
ATOM   6958  H  HA   . ALA   B 1 132 ? 33.003  -6.652  63.967  1.00 38.31  ?  131 ALA   A HA   1 
ATOM   6959  H  HB1  . ALA   B 1 132 ? 35.200  -7.266  63.593  1.00 40.40  ?  131 ALA   A HB1  1 
ATOM   6960  H  HB2  . ALA   B 1 132 ? 34.510  -8.398  64.468  1.00 40.40  ?  131 ALA   A HB2  1 
ATOM   6961  H  HB3  . ALA   B 1 132 ? 34.731  -8.621  62.911  1.00 40.40  ?  131 ALA   A HB3  1 
ATOM   6962  N  N    . LEU   B 1 133 ? 32.997  -7.520  60.886  1.00 31.53  ?  132 LEU   A N    1 
ATOM   6963  C  CA   . LEU   B 1 133 ? 33.002  -6.951  59.533  1.00 37.61  ?  132 LEU   A CA   1 
ATOM   6964  C  C    . LEU   B 1 133 ? 31.739  -6.147  59.296  1.00 34.60  ?  132 LEU   A C    1 
ATOM   6965  O  O    . LEU   B 1 133 ? 31.805  -5.021  58.781  1.00 31.98  ?  132 LEU   A O    1 
ATOM   6966  C  CB   . LEU   B 1 133 ? 33.144  -8.029  58.449  1.00 29.22  ?  132 LEU   A CB   1 
ATOM   6967  C  CG   . LEU   B 1 133 ? 34.558  -8.597  58.384  1.00 36.50  ?  132 LEU   A CG   1 
ATOM   6968  C  CD1  . LEU   B 1 133 ? 34.763  -9.733  57.421  1.00 34.33  ?  132 LEU   A CD1  1 
ATOM   6969  C  CD2  . LEU   B 1 133 ? 35.489  -7.415  58.052  1.00 33.64  ?  132 LEU   A CD2  1 
ATOM   6970  H  H    . LEU   B 1 133 ? 32.916  -8.375  60.926  1.00 37.84  ?  132 LEU   A H    1 
ATOM   6971  H  HA   . LEU   B 1 133 ? 33.779  -6.376  59.457  1.00 45.13  ?  132 LEU   A HA   1 
ATOM   6972  H  HB2  . LEU   B 1 133 ? 32.533  -8.757  58.643  1.00 35.07  ?  132 LEU   A HB2  1 
ATOM   6973  H  HB3  . LEU   B 1 133 ? 32.933  -7.640  57.585  1.00 35.07  ?  132 LEU   A HB3  1 
ATOM   6974  H  HG   . LEU   B 1 133 ? 34.764  -9.004  59.240  1.00 43.80  ?  132 LEU   A HG   1 
ATOM   6975  H  HD11 . LEU   B 1 133 ? 35.603  -10.174 57.626  1.00 41.20  ?  132 LEU   A HD11 1 
ATOM   6976  H  HD12 . LEU   B 1 133 ? 34.030  -10.361 57.512  1.00 41.20  ?  132 LEU   A HD12 1 
ATOM   6977  H  HD13 . LEU   B 1 133 ? 34.787  -9.381  56.517  1.00 41.20  ?  132 LEU   A HD13 1 
ATOM   6978  H  HD21 . LEU   B 1 133 ? 36.301  -7.758  57.646  1.00 40.37  ?  132 LEU   A HD21 1 
ATOM   6979  H  HD22 . LEU   B 1 133 ? 35.036  -6.820  57.434  1.00 40.37  ?  132 LEU   A HD22 1 
ATOM   6980  H  HD23 . LEU   B 1 133 ? 35.703  -6.942  58.871  1.00 40.37  ?  132 LEU   A HD23 1 
ATOM   6981  N  N    . GLN   B 1 134 ? 30.580  -6.696  59.691  1.00 28.83  ?  133 GLN   A N    1 
ATOM   6982  C  CA   . GLN   B 1 134 ? 29.325  -6.002  59.393  1.00 33.94  ?  133 GLN   A CA   1 
ATOM   6983  C  C    . GLN   B 1 134 ? 29.275  -4.647  60.088  1.00 31.28  ?  133 GLN   A C    1 
ATOM   6984  O  O    . GLN   B 1 134 ? 28.881  -3.641  59.488  1.00 33.48  ?  133 GLN   A O    1 
ATOM   6985  C  CB   . GLN   B 1 134 ? 28.093  -6.796  59.818  1.00 34.86  ?  133 GLN   A CB   1 
ATOM   6986  C  CG   . GLN   B 1 134 ? 28.154  -8.299  59.804  1.00 50.15  ?  133 GLN   A CG   1 
ATOM   6987  C  CD   . GLN   B 1 134 ? 26.951  -8.935  60.630  1.00 57.82  ?  133 GLN   A CD   1 
ATOM   6988  O  OE1  . GLN   B 1 134 ? 26.347  -8.278  61.481  1.00 65.85  ?  133 GLN   A OE1  1 
ATOM   6989  N  NE2  . GLN   B 1 134 ? 26.628  -10.202 60.356  1.00 57.54  ?  133 GLN   A NE2  1 
ATOM   6990  H  H    . GLN   B 1 134 ? 30.499  -7.439  60.116  1.00 34.60  ?  133 GLN   A H    1 
ATOM   6991  H  HA   . GLN   B 1 134 ? 29.296  -5.900  58.429  1.00 40.73  ?  133 GLN   A HA   1 
ATOM   6992  H  HB2  . GLN   B 1 134 ? 27.880  -6.539  60.728  1.00 41.83  ?  133 GLN   A HB2  1 
ATOM   6993  H  HB3  . GLN   B 1 134 ? 27.367  -6.546  59.225  1.00 41.83  ?  133 GLN   A HB3  1 
ATOM   6994  H  HG2  . GLN   B 1 134 ? 28.097  -8.615  58.889  1.00 60.18  ?  133 GLN   A HG2  1 
ATOM   6995  H  HG3  . GLN   B 1 134 ? 28.988  -8.591  60.205  1.00 60.18  ?  133 GLN   A HG3  1 
ATOM   6996  H  HE21 . GLN   B 1 134 ? 27.063  -10.637 59.755  1.00 69.05  ?  133 GLN   A HE21 1 
ATOM   6997  H  HE22 . GLN   B 1 134 ? 25.984  -10.583 60.780  1.00 69.05  ?  133 GLN   A HE22 1 
ATOM   6998  N  N    . ASP   B 1 135 ? 29.641  -4.608  61.382  1.00 30.93  ?  134 ASP   A N    1 
ATOM   6999  C  CA   . ASP   B 1 135 ? 29.605  -3.340  62.105  1.00 29.07  ?  134 ASP   A CA   1 
ATOM   7000  C  C    . ASP   B 1 135 ? 30.631  -2.367  61.520  1.00 38.00  ?  134 ASP   A C    1 
ATOM   7001  O  O    . ASP   B 1 135 ? 30.322  -1.191  61.292  1.00 36.79  ?  134 ASP   A O    1 
ATOM   7002  C  CB   . ASP   B 1 135 ? 29.840  -3.572  63.605  1.00 41.11  ?  134 ASP   A CB   1 
ATOM   7003  C  CG   . ASP   B 1 135 ? 28.801  -4.540  64.265  1.00 44.27  ?  134 ASP   A CG   1 
ATOM   7004  O  OD1  . ASP   B 1 135 ? 27.692  -4.795  63.718  1.00 47.89  ?  134 ASP   A OD1  1 
ATOM   7005  O  OD2  . ASP   B 1 135 ? 29.129  -5.073  65.352  1.00 41.88  ?  134 ASP   A OD2  1 
ATOM   7006  H  H    . ASP   B 1 135 ? 29.904  -5.283  61.844  1.00 37.12  ?  134 ASP   A H    1 
ATOM   7007  H  HA   . ASP   B 1 135 ? 28.725  -2.942  62.017  1.00 34.88  ?  134 ASP   A HA   1 
ATOM   7008  H  HB2  . ASP   B 1 135 ? 30.721  -3.957  63.727  1.00 49.34  ?  134 ASP   A HB2  1 
ATOM   7009  H  HB3  . ASP   B 1 135 ? 29.783  -2.720  64.065  1.00 49.34  ?  134 ASP   A HB3  1 
ATOM   7010  N  N    . ALA   B 1 136 ? 31.850  -2.847  61.225  1.00 35.55  ?  135 ALA   A N    1 
ATOM   7011  C  CA   . ALA   B 1 136 ? 32.831  -1.987  60.566  1.00 32.90  ?  135 ALA   A CA   1 
ATOM   7012  C  C    . ALA   B 1 136 ? 32.328  -1.489  59.214  1.00 33.66  ?  135 ALA   A C    1 
ATOM   7013  O  O    . ALA   B 1 136 ? 32.546  -0.326  58.846  1.00 33.25  ?  135 ALA   A O    1 
ATOM   7014  C  CB   . ALA   B 1 136 ? 34.157  -2.729  60.388  1.00 36.40  ?  135 ALA   A CB   1 
ATOM   7015  H  H    . ALA   B 1 136 ? 32.122  -3.646  61.393  1.00 42.66  ?  135 ALA   A H    1 
ATOM   7016  H  HA   . ALA   B 1 136 ? 32.984  -1.216  61.135  1.00 39.48  ?  135 ALA   A HA   1 
ATOM   7017  H  HB1  . ALA   B 1 136 ? 34.794  -2.137  59.958  1.00 43.68  ?  135 ALA   A HB1  1 
ATOM   7018  H  HB2  . ALA   B 1 136 ? 34.489  -2.995  61.260  1.00 43.68  ?  135 ALA   A HB2  1 
ATOM   7019  H  HB3  . ALA   B 1 136 ? 34.009  -3.513  59.836  1.00 43.68  ?  135 ALA   A HB3  1 
ATOM   7020  N  N    . TYR   B 1 137 ? 31.678  -2.357  58.440  1.00 33.35  ?  136 TYR   A N    1 
ATOM   7021  C  CA   . TYR   B 1 137 ? 31.204  -1.944  57.121  1.00 39.96  ?  136 TYR   A CA   1 
ATOM   7022  C  C    . TYR   B 1 137 ? 30.191  -0.805  57.226  1.00 41.79  ?  136 TYR   A C    1 
ATOM   7023  O  O    . TYR   B 1 137 ? 30.243  0.160   56.451  1.00 37.97  ?  136 TYR   A O    1 
ATOM   7024  C  CB   . TYR   B 1 137 ? 30.593  -3.134  56.385  1.00 39.13  ?  136 TYR   A CB   1 
ATOM   7025  C  CG   . TYR   B 1 137 ? 30.230  -2.829  54.974  1.00 50.65  ?  136 TYR   A CG   1 
ATOM   7026  C  CD1  . TYR   B 1 137 ? 31.099  -2.157  54.157  1.00 52.11  ?  136 TYR   A CD1  1 
ATOM   7027  C  CD2  . TYR   B 1 137 ? 29.008  -3.215  54.452  1.00 82.34  ?  136 TYR   A CD2  1 
ATOM   7028  C  CE1  . TYR   B 1 137 ? 30.779  -1.890  52.848  1.00 66.19  ?  136 TYR   A CE1  1 
ATOM   7029  C  CE2  . TYR   B 1 137 ? 28.674  -2.948  53.160  1.00 113.03 ?  136 TYR   A CE2  1 
ATOM   7030  C  CZ   . TYR   B 1 137 ? 29.566  -2.288  52.355  1.00 69.62  ?  136 TYR   A CZ   1 
ATOM   7031  O  OH   . TYR   B 1 137 ? 29.250  -2.009  51.053  1.00 60.57  ?  136 TYR   A OH   1 
ATOM   7032  H  H    . TYR   B 1 137 ? 31.502  -3.172  58.650  1.00 40.02  ?  136 TYR   A H    1 
ATOM   7033  H  HA   . TYR   B 1 137 ? 31.963  -1.626  56.607  1.00 47.95  ?  136 TYR   A HA   1 
ATOM   7034  H  HB2  . TYR   B 1 137 ? 31.235  -3.862  56.378  1.00 46.95  ?  136 TYR   A HB2  1 
ATOM   7035  H  HB3  . TYR   B 1 137 ? 29.786  -3.409  56.849  1.00 46.95  ?  136 TYR   A HB3  1 
ATOM   7036  H  HD1  . TYR   B 1 137 ? 31.919  -1.877  54.493  1.00 62.53  ?  136 TYR   A HD1  1 
ATOM   7037  H  HD2  . TYR   B 1 137 ? 28.402  -3.667  54.994  1.00 98.81  ?  136 TYR   A HD2  1 
ATOM   7038  H  HE1  . TYR   B 1 137 ? 31.382  -1.442  52.301  1.00 79.43  ?  136 TYR   A HE1  1 
ATOM   7039  H  HE2  . TYR   B 1 137 ? 27.846  -3.210  52.826  1.00 135.63 ?  136 TYR   A HE2  1 
ATOM   7040  H  HH   . TYR   B 1 137 ? 28.492  -2.320  50.868  1.00 72.69  ?  136 TYR   A HH   1 
ATOM   7041  N  N    . TYR   B 1 138 ? 29.216  -0.926  58.150  1.00 49.33  ?  137 TYR   A N    1 
ATOM   7042  C  CA   . TYR   B 1 138 ? 28.237  0.150   58.369  1.00 43.96  ?  137 TYR   A CA   1 
ATOM   7043  C  C    . TYR   B 1 138 ? 28.962  1.453   58.692  1.00 40.65  ?  137 TYR   A C    1 
ATOM   7044  O  O    . TYR   B 1 138 ? 28.713  2.503   58.072  1.00 35.02  ?  137 TYR   A O    1 
ATOM   7045  C  CB   . TYR   B 1 138 ? 27.264  -0.256  59.500  1.00 52.98  ?  137 TYR   A CB   1 
ATOM   7046  C  CG   . TYR   B 1 138 ? 26.331  0.842   60.000  1.00 66.24  ?  137 TYR   A CG   1 
ATOM   7047  C  CD1  . TYR   B 1 138 ? 25.031  0.979   59.487  1.00 71.16  ?  137 TYR   A CD1  1 
ATOM   7048  C  CD2  . TYR   B 1 138 ? 26.729  1.718   61.005  1.00 95.78  ?  137 TYR   A CD2  1 
ATOM   7049  C  CE1  . TYR   B 1 138 ? 24.164  1.975   59.951  1.00 70.82  ?  137 TYR   A CE1  1 
ATOM   7050  C  CE2  . TYR   B 1 138 ? 25.874  2.718   61.467  1.00 66.85  ?  137 TYR   A CE2  1 
ATOM   7051  C  CZ   . TYR   B 1 138 ? 24.595  2.838   60.935  1.00 69.54  ?  137 TYR   A CZ   1 
ATOM   7052  O  OH   . TYR   B 1 138 ? 23.752  3.825   61.403  1.00 78.71  ?  137 TYR   A OH   1 
ATOM   7053  H  H    . TYR   B 1 138 ? 29.103  -1.613  58.655  1.00 59.19  ?  137 TYR   A H    1 
ATOM   7054  H  HA   . TYR   B 1 138 ? 27.707  0.290   57.568  1.00 52.75  ?  137 TYR   A HA   1 
ATOM   7055  H  HB2  . TYR   B 1 138 ? 26.707  -0.981  59.176  1.00 63.58  ?  137 TYR   A HB2  1 
ATOM   7056  H  HB3  . TYR   B 1 138 ? 27.789  -0.555  60.259  1.00 63.58  ?  137 TYR   A HB3  1 
ATOM   7057  H  HD1  . TYR   B 1 138 ? 24.739  0.395   58.824  1.00 85.39  ?  137 TYR   A HD1  1 
ATOM   7058  H  HD2  . TYR   B 1 138 ? 27.578  1.634   61.375  1.00 114.93 ?  137 TYR   A HD2  1 
ATOM   7059  H  HE1  . TYR   B 1 138 ? 23.307  2.053   59.599  1.00 84.98  ?  137 TYR   A HE1  1 
ATOM   7060  H  HE2  . TYR   B 1 138 ? 26.160  3.305   62.130  1.00 80.22  ?  137 TYR   A HE2  1 
ATOM   7061  H  HH   . TYR   B 1 138 ? 24.153  4.303   61.965  1.00 94.45  ?  137 TYR   A HH   1 
ATOM   7062  N  N    . ARG   B 1 139 ? 29.906  1.380   59.649  1.00 35.19  ?  138 ARG   A N    1 
ATOM   7063  C  CA   . ARG   B 1 139 ? 30.720  2.543   60.023  1.00 39.00  ?  138 ARG   A CA   1 
ATOM   7064  C  C    . ARG   B 1 139 ? 31.450  3.103   58.803  1.00 37.56  ?  138 ARG   A C    1 
ATOM   7065  O  O    . ARG   B 1 139 ? 31.467  4.317   58.570  1.00 35.83  ?  138 ARG   A O    1 
ATOM   7066  C  CB   . ARG   B 1 139 ? 31.734  2.165   61.119  1.00 43.30  ?  138 ARG   A CB   1 
ATOM   7067  C  CG   . ARG   B 1 139 ? 31.233  2.121   62.566  1.00 42.66  ?  138 ARG   A CG   1 
ATOM   7068  C  CD   . ARG   B 1 139 ? 32.214  2.809   63.529  1.00 47.93  ?  138 ARG   A CD   1 
ATOM   7069  N  NE   . ARG   B 1 139 ? 32.206  4.248   63.253  1.00 63.23  ?  138 ARG   A NE   1 
ATOM   7070  C  CZ   . ARG   B 1 139 ? 33.020  5.150   63.791  1.00 74.28  ?  138 ARG   A CZ   1 
ATOM   7071  N  NH1  . ARG   B 1 139 ? 33.944  4.810   64.675  1.00 75.92  ?  138 ARG   A NH1  1 
ATOM   7072  N  NH2  . ARG   B 1 139 ? 32.886  6.433   63.448  1.00 62.03  ?  138 ARG   A NH2  1 
ATOM   7073  H  H    . ARG   B 1 139 ? 30.092  0.668   60.094  1.00 42.23  ?  138 ARG   A H    1 
ATOM   7074  H  HA   . ARG   B 1 139 ? 30.134  3.227   60.382  1.00 46.80  ?  138 ARG   A HA   1 
ATOM   7075  H  HB2  . ARG   B 1 139 ? 32.076  1.280   60.914  1.00 51.96  ?  138 ARG   A HB2  1 
ATOM   7076  H  HB3  . ARG   B 1 139 ? 32.455  2.813   61.092  1.00 51.96  ?  138 ARG   A HB3  1 
ATOM   7077  H  HG2  . ARG   B 1 139 ? 30.380  2.578   62.624  1.00 51.19  ?  138 ARG   A HG2  1 
ATOM   7078  H  HG3  . ARG   B 1 139 ? 31.134  1.196   62.843  1.00 51.19  ?  138 ARG   A HG3  1 
ATOM   7079  H  HD2  . ARG   B 1 139 ? 31.939  2.660   64.447  1.00 57.51  ?  138 ARG   A HD2  1 
ATOM   7080  H  HD3  . ARG   B 1 139 ? 33.111  2.465   63.392  1.00 57.51  ?  138 ARG   A HD3  1 
ATOM   7081  H  HE   . ARG   B 1 139 ? 31.620  4.535   62.693  1.00 75.88  ?  138 ARG   A HE   1 
ATOM   7082  H  HH11 . ARG   B 1 139 ? 34.029  3.989   64.915  1.00 91.10  ?  138 ARG   A HH11 1 
ATOM   7083  H  HH12 . ARG   B 1 139 ? 34.461  5.411   65.010  1.00 91.10  ?  138 ARG   A HH12 1 
ATOM   7084  H  HH21 . ARG   B 1 139 ? 32.278  6.667   62.886  1.00 74.43  ?  138 ARG   A HH21 1 
ATOM   7085  H  HH22 . ARG   B 1 139 ? 33.406  7.026   63.789  1.00 74.43  ?  138 ARG   A HH22 1 
ATOM   7086  N  N    . ALA   B 1 140 ? 32.040  2.217   57.995  1.00 36.86  ?  139 ALA   A N    1 
ATOM   7087  C  CA   . ALA   B 1 140 ? 32.711  2.642   56.770  1.00 39.37  ?  139 ALA   A CA   1 
ATOM   7088  C  C    . ALA   B 1 140 ? 31.750  3.332   55.804  1.00 34.18  ?  139 ALA   A C    1 
ATOM   7089  O  O    . ALA   B 1 140 ? 32.035  4.421   55.289  1.00 32.18  ?  139 ALA   A O    1 
ATOM   7090  C  CB   . ALA   B 1 140 ? 33.341  1.427   56.094  1.00 33.00  ?  139 ALA   A CB   1 
ATOM   7091  H  H    . ALA   B 1 140 ? 32.064  1.368   58.134  1.00 44.23  ?  139 ALA   A H    1 
ATOM   7092  H  HA   . ALA   B 1 140 ? 33.405  3.278   57.004  1.00 47.25  ?  139 ALA   A HA   1 
ATOM   7093  H  HB1  . ALA   B 1 140 ? 33.744  1.705   55.256  1.00 39.60  ?  139 ALA   A HB1  1 
ATOM   7094  H  HB2  . ALA   B 1 140 ? 34.020  1.056   56.680  1.00 39.60  ?  139 ALA   A HB2  1 
ATOM   7095  H  HB3  . ALA   B 1 140 ? 32.652  0.766   55.927  1.00 39.60  ?  139 ALA   A HB3  1 
ATOM   7096  N  N    . ARG   B 1 141 ? 30.629  2.717   55.522  1.00 35.41  ?  140 ARG   A N    1 
ATOM   7097  C  CA   . ARG   B 1 141 ? 29.668  3.282   54.604  1.00 36.07  ?  140 ARG   A CA   1 
ATOM   7098  C  C    . ARG   B 1 141 ? 29.218  4.671   55.032  1.00 38.39  ?  140 ARG   A C    1 
ATOM   7099  O  O    . ARG   B 1 141 ? 28.897  5.493   54.218  1.00 34.06  ?  140 ARG   A O    1 
ATOM   7100  C  CB   . ARG   B 1 141 ? 28.492  2.369   54.493  1.00 32.09  ?  140 ARG   A CB   1 
ATOM   7101  C  CG   . ARG   B 1 141 ? 27.247  3.107   54.106  1.00 54.28  ?  140 ARG   A CG   1 
ATOM   7102  C  CD   . ARG   B 1 141 ? 26.095  2.168   53.877  1.00 61.90  ?  140 ARG   A CD   1 
ATOM   7103  N  NE   . ARG   B 1 141 ? 26.472  1.117   52.968  1.00 79.19  ?  140 ARG   A NE   1 
ATOM   7104  C  CZ   . ARG   B 1 141 ? 25.630  0.547   52.135  1.00 76.07  ?  140 ARG   A CZ   1 
ATOM   7105  N  NH1  . ARG   B 1 141 ? 26.057  -0.410  51.329  1.00 58.80  ?  140 ARG   A NH1  1 
ATOM   7106  N  NH2  . ARG   B 1 141 ? 24.357  0.944   52.123  1.00 74.08  ?  140 ARG   A NH2  1 
ATOM   7107  H  H    . ARG   B 1 141 ? 30.395  1.958   55.852  1.00 42.49  ?  140 ARG   A H    1 
ATOM   7108  H  HA   . ARG   B 1 141 ? 30.079  3.357   53.718  1.00 43.28  ?  140 ARG   A HA   1 
ATOM   7109  H  HB2  . ARG   B 1 141 ? 28.670  1.699   53.815  1.00 38.50  ?  140 ARG   A HB2  1 
ATOM   7110  H  HB3  . ARG   B 1 141 ? 28.337  1.944   55.351  1.00 38.50  ?  140 ARG   A HB3  1 
ATOM   7111  H  HG2  . ARG   B 1 141 ? 26.992  3.711   54.821  1.00 65.14  ?  140 ARG   A HG2  1 
ATOM   7112  H  HG3  . ARG   B 1 141 ? 27.407  3.601   53.287  1.00 65.14  ?  140 ARG   A HG3  1 
ATOM   7113  H  HD2  . ARG   B 1 141 ? 25.831  1.767   54.720  1.00 74.28  ?  140 ARG   A HD2  1 
ATOM   7114  H  HD3  . ARG   B 1 141 ? 25.354  2.658   53.487  1.00 74.28  ?  140 ARG   A HD3  1 
ATOM   7115  H  HE   . ARG   B 1 141 ? 27.418  0.966   52.818  1.00 95.03  ?  140 ARG   A HE   1 
ATOM   7116  H  HH11 . ARG   B 1 141 ? 26.876  -0.634  51.363  1.00 70.56  ?  140 ARG   A HH11 1 
ATOM   7117  H  HH12 . ARG   B 1 141 ? 25.520  -0.795  50.779  1.00 70.56  ?  140 ARG   A HH12 1 
ATOM   7118  H  HH21 . ARG   B 1 141 ? 24.084  1.566   52.650  1.00 88.89  ?  140 ARG   A HH21 1 
ATOM   7119  H  HH22 . ARG   B 1 141 ? 23.801  0.573   51.582  1.00 88.89  ?  140 ARG   A HH22 1 
ATOM   7120  N  N    . ALA   B 1 142 ? 29.202  4.893   56.338  1.00 42.35  ?  141 ALA   A N    1 
ATOM   7121  C  CA   . ALA   B 1 142 ? 28.877  6.154   56.948  1.00 37.00  ?  141 ALA   A CA   1 
ATOM   7122  C  C    . ALA   B 1 142 ? 29.970  7.214   56.947  1.00 41.55  ?  141 ALA   A C    1 
ATOM   7123  O  O    . ALA   B 1 142 ? 29.740  8.292   57.413  1.00 39.27  ?  141 ALA   A O    1 
ATOM   7124  C  CB   . ALA   B 1 142 ? 28.456  5.890   58.373  1.00 33.54  ?  141 ALA   A CB   1 
ATOM   7125  H  H    . ALA   B 1 142 ? 29.280  4.285   56.939  1.00 50.82  ?  141 ALA   A H    1 
ATOM   7126  H  HA   . ALA   B 1 142 ? 28.104  6.532   56.479  1.00 44.40  ?  141 ALA   A HA   1 
ATOM   7127  H  HB1  . ALA   B 1 142 ? 28.219  6.722   58.788  1.00 40.25  ?  141 ALA   A HB1  1 
ATOM   7128  H  HB2  . ALA   B 1 142 ? 27.701  5.297   58.371  1.00 40.25  ?  141 ALA   A HB2  1 
ATOM   7129  H  HB3  . ALA   B 1 142 ? 29.188  5.485   58.845  1.00 40.25  ?  141 ALA   A HB3  1 
ATOM   7130  N  N    . GLY   B 1 143 ? 31.169  6.907   56.488  1.00 39.66  ?  142 GLY   A N    1 
ATOM   7131  C  CA   . GLY   B 1 143 ? 32.221  7.876   56.457  1.00 33.99  ?  142 GLY   A CA   1 
ATOM   7132  C  C    . GLY   B 1 143 ? 33.443  7.602   57.274  1.00 43.37  ?  142 GLY   A C    1 
ATOM   7133  O  O    . GLY   B 1 143 ? 34.428  8.258   57.068  1.00 44.01  ?  142 GLY   A O    1 
ATOM   7134  H  H    . GLY   B 1 143 ? 31.410  6.164   56.187  1.00 47.59  ?  142 GLY   A H    1 
ATOM   7135  H  HA2  . GLY   B 1 143 ? 32.511  8.030   55.553  1.00 40.79  ?  142 GLY   A HA2  1 
ATOM   7136  H  HA3  . GLY   B 1 143 ? 31.854  8.714   56.779  1.00 40.79  ?  142 GLY   A HA3  1 
ATOM   7137  N  N    . GLU   B 1 144 ? 33.390  6.676   58.213  1.00 43.02  ?  143 GLU   A N    1 
ATOM   7138  C  CA   . GLU   B 1 144 ? 34.543  6.399   59.045  1.00 42.22  ?  143 GLU   A CA   1 
ATOM   7139  C  C    . GLU   B 1 144 ? 34.966  4.941   58.900  1.00 38.72  ?  143 GLU   A C    1 
ATOM   7140  O  O    . GLU   B 1 144 ? 34.455  4.109   59.558  1.00 40.08  ?  143 GLU   A O    1 
ATOM   7141  C  CB   . GLU   B 1 144 ? 34.209  6.703   60.481  1.00 49.57  ?  143 GLU   A CB   1 
ATOM   7142  C  CG   . GLU   B 1 144 ? 35.108  7.747   61.083  1.00 60.15  ?  143 GLU   A CG   1 
ATOM   7143  C  CD   . GLU   B 1 144 ? 36.577  7.586   60.699  1.00 64.88  ?  143 GLU   A CD   1 
ATOM   7144  O  OE1  . GLU   B 1 144 ? 37.192  6.510   60.978  1.00 50.51  ?  143 GLU   A OE1  1 
ATOM   7145  O  OE2  . GLU   B 1 144 ? 37.098  8.563   60.116  1.00 65.69  ?  143 GLU   A OE2  1 
ATOM   7146  H  H    . GLU   B 1 144 ? 32.699  6.196   58.390  1.00 51.63  ?  143 GLU   A H    1 
ATOM   7147  H  HA   . GLU   B 1 144 ? 35.233  7.029   58.760  1.00 50.67  ?  143 GLU   A HA   1 
ATOM   7148  H  HB2  . GLU   B 1 144 ? 33.297  7.028   60.531  1.00 59.48  ?  143 GLU   A HB2  1 
ATOM   7149  H  HB3  . GLU   B 1 144 ? 34.300  5.891   61.004  1.00 59.48  ?  143 GLU   A HB3  1 
ATOM   7150  H  HG2  . GLU   B 1 144 ? 34.817  8.622   60.780  1.00 72.18  ?  143 GLU   A HG2  1 
ATOM   7151  H  HG3  . GLU   B 1 144 ? 35.045  7.695   62.049  1.00 72.18  ?  143 GLU   A HG3  1 
ATOM   7152  N  N    . ALA   B 1 145 ? 36.007  4.670   58.143  1.00 43.61  ?  144 ALA   A N    1 
ATOM   7153  C  CA   . ALA   B 1 145 ? 36.337  3.313   57.746  1.00 37.05  ?  144 ALA   A CA   1 
ATOM   7154  C  C    . ALA   B 1 145 ? 37.580  2.780   58.428  1.00 33.45  ?  144 ALA   A C    1 
ATOM   7155  O  O    . ALA   B 1 145 ? 38.104  1.741   57.997  1.00 38.17  ?  144 ALA   A O    1 
ATOM   7156  C  CB   . ALA   B 1 145 ? 36.506  3.246   56.223  1.00 34.18  ?  144 ALA   A CB   1 
ATOM   7157  H  H    . ALA   B 1 145 ? 36.523  5.270   57.805  1.00 52.33  ?  144 ALA   A H    1 
ATOM   7158  H  HA   . ALA   B 1 145 ? 35.601  2.734   58.000  1.00 44.46  ?  144 ALA   A HA   1 
ATOM   7159  H  HB1  . ALA   B 1 145 ? 36.649  2.324   55.962  1.00 41.02  ?  144 ALA   A HB1  1 
ATOM   7160  H  HB2  . ALA   B 1 145 ? 35.703  3.589   55.801  1.00 41.02  ?  144 ALA   A HB2  1 
ATOM   7161  H  HB3  . ALA   B 1 145 ? 37.270  3.786   55.967  1.00 41.02  ?  144 ALA   A HB3  1 
ATOM   7162  N  N    . ALA   B 1 146 ? 38.079  3.448   59.471  1.00 37.67  ?  145 ALA   A N    1 
ATOM   7163  C  CA   . ALA   B 1 146 ? 39.386  3.040   60.009  1.00 35.84  ?  145 ALA   A CA   1 
ATOM   7164  C  C    . ALA   B 1 146 ? 39.324  1.625   60.557  1.00 34.76  ?  145 ALA   A C    1 
ATOM   7165  O  O    . ALA   B 1 146 ? 40.253  0.828   60.373  1.00 31.67  ?  145 ALA   A O    1 
ATOM   7166  C  CB   . ALA   B 1 146 ? 39.880  3.978   61.115  1.00 37.83  ?  145 ALA   A CB   1 
ATOM   7167  H  H    . ALA   B 1 146 ? 37.701  4.110   59.870  1.00 45.20  ?  145 ALA   A H    1 
ATOM   7168  H  HA   . ALA   B 1 146 ? 40.022  3.093   59.278  1.00 43.01  ?  145 ALA   A HA   1 
ATOM   7169  H  HB1  . ALA   B 1 146 ? 40.693  3.613   61.498  1.00 45.40  ?  145 ALA   A HB1  1 
ATOM   7170  H  HB2  . ALA   B 1 146 ? 40.057  4.851   60.733  1.00 45.40  ?  145 ALA   A HB2  1 
ATOM   7171  H  HB3  . ALA   B 1 146 ? 39.194  4.048   61.798  1.00 45.40  ?  145 ALA   A HB3  1 
ATOM   7172  N  N    . ASN   B 1 147 ? 38.219  1.272   61.214  1.00 35.78  ?  146 ASN   A N    1 
ATOM   7173  C  CA   . ASN   B 1 147 ? 38.121  -0.093  61.719  1.00 39.04  ?  146 ASN   A CA   1 
ATOM   7174  C  C    . ASN   B 1 147 ? 37.997  -1.119  60.593  1.00 42.21  ?  146 ASN   A C    1 
ATOM   7175  O  O    . ASN   B 1 147 ? 38.661  -2.173  60.665  1.00 30.95  ?  146 ASN   A O    1 
ATOM   7176  C  CB   . ASN   B 1 147 ? 36.960  -0.216  62.683  1.00 40.14  ?  146 ASN   A CB   1 
ATOM   7177  C  CG   . ASN   B 1 147 ? 37.225  0.509   63.936  1.00 40.07  ?  146 ASN   A CG   1 
ATOM   7178  O  OD1  . ASN   B 1 147 ? 36.785  1.637   64.106  1.00 41.95  ?  146 ASN   A OD1  1 
ATOM   7179  N  ND2  . ASN   B 1 147 ? 38.037  -0.106  64.815  1.00 37.01  ?  146 ASN   A ND2  1 
ATOM   7180  H  H    . ASN   B 1 147 ? 37.544  1.780   61.372  1.00 42.93  ?  146 ASN   A H    1 
ATOM   7181  H  HA   . ASN   B 1 147 ? 38.938  -0.291  62.203  1.00 46.85  ?  146 ASN   A HA   1 
ATOM   7182  H  HB2  . ASN   B 1 147 ? 36.163  0.158   62.276  1.00 48.17  ?  146 ASN   A HB2  1 
ATOM   7183  H  HB3  . ASN   B 1 147 ? 36.817  -1.152  62.895  1.00 48.17  ?  146 ASN   A HB3  1 
ATOM   7184  H  HD21 . ASN   B 1 147 ? 38.368  -0.877  64.628  1.00 44.41  ?  146 ASN   A HD21 1 
ATOM   7185  H  HD22 . ASN   B 1 147 ? 38.225  0.272   65.564  1.00 44.41  ?  146 ASN   A HD22 1 
ATOM   7186  N  N    . PHE   B 1 148 ? 37.161  -0.821  59.553  1.00 30.26  ?  147 PHE   A N    1 
ATOM   7187  C  CA   . PHE   B 1 148 ? 37.017  -1.710  58.385  1.00 35.27  ?  147 PHE   A CA   1 
ATOM   7188  C  C    . PHE   B 1 148 ? 38.368  -1.955  57.716  1.00 34.53  ?  147 PHE   A C    1 
ATOM   7189  O  O    . PHE   B 1 148 ? 38.807  -3.099  57.582  1.00 34.12  ?  147 PHE   A O    1 
ATOM   7190  C  CB   . PHE   B 1 148 ? 35.998  -1.151  57.364  1.00 35.13  ?  147 PHE   A CB   1 
ATOM   7191  C  CG   . PHE   B 1 148 ? 35.483  -2.206  56.372  1.00 47.12  ?  147 PHE   A CG   1 
ATOM   7192  C  CD1  . PHE   B 1 148 ? 34.819  -3.353  56.819  1.00 38.93  ?  147 PHE   A CD1  1 
ATOM   7193  C  CD2  . PHE   B 1 148 ? 35.688  -2.073  55.001  1.00 40.84  ?  147 PHE   A CD2  1 
ATOM   7194  C  CE1  . PHE   B 1 148 ? 34.390  -4.345  55.916  1.00 38.90  ?  147 PHE   A CE1  1 
ATOM   7195  C  CE2  . PHE   B 1 148 ? 35.217  -3.059  54.111  1.00 46.65  ?  147 PHE   A CE2  1 
ATOM   7196  C  CZ   . PHE   B 1 148 ? 34.573  -4.184  54.569  1.00 42.26  ?  147 PHE   A CZ   1 
ATOM   7197  H  H    . PHE   B 1 148 ? 36.674  -0.113  59.510  1.00 36.31  ?  147 PHE   A H    1 
ATOM   7198  H  HA   . PHE   B 1 148 ? 36.666  -2.558  58.700  1.00 42.32  ?  147 PHE   A HA   1 
ATOM   7199  H  HB2  . PHE   B 1 148 ? 35.234  -0.798  57.846  1.00 42.15  ?  147 PHE   A HB2  1 
ATOM   7200  H  HB3  . PHE   B 1 148 ? 36.423  -0.445  56.853  1.00 42.15  ?  147 PHE   A HB3  1 
ATOM   7201  H  HD1  . PHE   B 1 148 ? 34.659  -3.462  57.728  1.00 46.72  ?  147 PHE   A HD1  1 
ATOM   7202  H  HD2  . PHE   B 1 148 ? 36.139  -1.330  54.671  1.00 49.01  ?  147 PHE   A HD2  1 
ATOM   7203  H  HE1  . PHE   B 1 148 ? 33.979  -5.115  56.237  1.00 46.68  ?  147 PHE   A HE1  1 
ATOM   7204  H  HE2  . PHE   B 1 148 ? 35.344  -2.946  53.196  1.00 55.98  ?  147 PHE   A HE2  1 
ATOM   7205  H  HZ   . PHE   B 1 148 ? 34.266  -4.828  53.972  1.00 50.71  ?  147 PHE   A HZ   1 
ATOM   7206  N  N    . CYS   B 1 149 ? 39.083  -0.890  57.386  1.00 34.39  ?  148 CYS   A N    1 
ATOM   7207  C  CA   . CYS   B 1 149 ? 40.411  -1.026  56.786  1.00 31.74  ?  148 CYS   A CA   1 
ATOM   7208  C  C    . CYS   B 1 149 ? 41.365  -1.837  57.645  1.00 35.79  ?  148 CYS   A C    1 
ATOM   7209  O  O    . CYS   B 1 149 ? 42.019  -2.764  57.154  1.00 35.36  ?  148 CYS   A O    1 
ATOM   7210  C  CB   . CYS   B 1 149 ? 40.975  0.356   56.535  1.00 32.27  ?  148 CYS   A CB   1 
ATOM   7211  S  SG   . CYS   B 1 149 ? 40.095  1.052   55.120  1.00 45.18  ?  148 CYS   A SG   1 
ATOM   7212  H  H    . CYS   B 1 149 ? 38.828  -0.077  57.496  1.00 41.26  ?  148 CYS   A H    1 
ATOM   7213  H  HA   . CYS   B 1 149 ? 40.321  -1.500  55.945  1.00 38.08  ?  148 CYS   A HA   1 
ATOM   7214  H  HB2  . CYS   B 1 149 ? 40.836  0.921   57.311  1.00 38.73  ?  148 CYS   A HB2  1 
ATOM   7215  H  HB3  . CYS   B 1 149 ? 41.921  0.301   56.331  1.00 38.73  ?  148 CYS   A HB3  1 
ATOM   7216  H  HG   . CYS   B 1 149 ? 40.447  2.188   54.961  1.00 54.22  ?  148 CYS   A HG   1 
ATOM   7217  N  N    . ALA   B 1 150 ? 41.430  -1.538  58.945  1.00 37.98  ?  149 ALA   A N    1 
ATOM   7218  C  CA   . ALA   B 1 150 ? 42.280  -2.340  59.823  1.00 38.79  ?  149 ALA   A CA   1 
ATOM   7219  C  C    . ALA   B 1 150 ? 41.871  -3.811  59.800  1.00 36.52  ?  149 ALA   A C    1 
ATOM   7220  O  O    . ALA   B 1 150 ? 42.731  -4.695  59.799  1.00 33.27  ?  149 ALA   A O    1 
ATOM   7221  C  CB   . ALA   B 1 150 ? 42.234  -1.792  61.250  1.00 33.83  ?  149 ALA   A CB   1 
ATOM   7222  H  H    . ALA   B 1 150 ? 41.005  -0.897  59.331  1.00 45.58  ?  149 ALA   A H    1 
ATOM   7223  H  HA   . ALA   B 1 150 ? 43.195  -2.277  59.508  1.00 46.55  ?  149 ALA   A HA   1 
ATOM   7224  H  HB1  . ALA   B 1 150 ? 42.855  -2.293  61.801  1.00 40.60  ?  149 ALA   A HB1  1 
ATOM   7225  H  HB2  . ALA   B 1 150 ? 42.485  -0.855  61.237  1.00 40.60  ?  149 ALA   A HB2  1 
ATOM   7226  H  HB3  . ALA   B 1 150 ? 41.333  -1.888  61.596  1.00 40.60  ?  149 ALA   A HB3  1 
ATOM   7227  N  N    . LEU   B 1 151 ? 40.565  -4.096  59.741  1.00 30.49  ?  150 LEU   A N    1 
ATOM   7228  C  CA   . LEU   B 1 151 ? 40.117  -5.483  59.795  1.00 34.96  ?  150 LEU   A CA   1 
ATOM   7229  C  C    . LEU   B 1 151 ? 40.457  -6.218  58.512  1.00 33.45  ?  150 LEU   A C    1 
ATOM   7230  O  O    . LEU   B 1 151 ? 40.812  -7.403  58.537  1.00 36.34  ?  150 LEU   A O    1 
ATOM   7231  C  CB   . LEU   B 1 151 ? 38.602  -5.559  60.024  1.00 39.03  ?  150 LEU   A CB   1 
ATOM   7232  C  CG   . LEU   B 1 151 ? 38.040  -5.185  61.389  1.00 35.94  ?  150 LEU   A CG   1 
ATOM   7233  C  CD1  . LEU   B 1 151 ? 36.530  -5.037  61.409  1.00 30.27  ?  150 LEU   A CD1  1 
ATOM   7234  C  CD2  . LEU   B 1 151 ? 38.471  -6.261  62.374  1.00 35.38  ?  150 LEU   A CD2  1 
ATOM   7235  H  H    . LEU   B 1 151 ? 39.934  -3.515  59.672  1.00 36.58  ?  150 LEU   A H    1 
ATOM   7236  H  HA   . LEU   B 1 151 ? 40.564  -5.911  60.543  1.00 41.96  ?  150 LEU   A HA   1 
ATOM   7237  H  HB2  . LEU   B 1 151 ? 38.182  -4.964  59.383  1.00 46.83  ?  150 LEU   A HB2  1 
ATOM   7238  H  HB3  . LEU   B 1 151 ? 38.328  -6.474  59.856  1.00 46.83  ?  150 LEU   A HB3  1 
ATOM   7239  H  HG   . LEU   B 1 151 ? 38.384  -4.313  61.637  1.00 43.12  ?  150 LEU   A HG   1 
ATOM   7240  H  HD11 . LEU   B 1 151 ? 36.267  -4.594  62.231  1.00 36.32  ?  150 LEU   A HD11 1 
ATOM   7241  H  HD12 . LEU   B 1 151 ? 36.254  -4.508  60.644  1.00 36.32  ?  150 LEU   A HD12 1 
ATOM   7242  H  HD13 . LEU   B 1 151 ? 36.126  -5.918  61.364  1.00 36.32  ?  150 LEU   A HD13 1 
ATOM   7243  H  HD21 . LEU   B 1 151 ? 37.913  -6.207  63.165  1.00 42.46  ?  150 LEU   A HD21 1 
ATOM   7244  H  HD22 . LEU   B 1 151 ? 38.370  -7.131  61.956  1.00 42.46  ?  150 LEU   A HD22 1 
ATOM   7245  H  HD23 . LEU   B 1 151 ? 39.400  -6.115  62.614  1.00 42.46  ?  150 LEU   A HD23 1 
ATOM   7246  N  N    . ILE   B 1 152 ? 40.349  -5.535  57.374  1.00 32.57  ?  151 ILE   A N    1 
ATOM   7247  C  CA   . ILE   B 1 152 ? 40.753  -6.162  56.116  1.00 37.10  ?  151 ILE   A CA   1 
ATOM   7248  C  C    . ILE   B 1 152 ? 42.212  -6.568  56.185  1.00 35.27  ?  151 ILE   A C    1 
ATOM   7249  O  O    . ILE   B 1 152 ? 42.578  -7.690  55.825  1.00 39.56  ?  151 ILE   A O    1 
ATOM   7250  C  CB   . ILE   B 1 152 ? 40.486  -5.225  54.929  1.00 34.91  ?  151 ILE   A CB   1 
ATOM   7251  C  CG1  . ILE   B 1 152 ? 38.995  -5.227  54.635  1.00 36.07  ?  151 ILE   A CG1  1 
ATOM   7252  C  CG2  . ILE   B 1 152 ? 41.211  -5.671  53.707  1.00 32.96  ?  151 ILE   A CG2  1 
ATOM   7253  C  CD1  . ILE   B 1 152 ? 38.524  -3.902  54.144  1.00 38.76  ?  151 ILE   A CD1  1 
ATOM   7254  H  H    . ILE   B 1 152 ? 40.053  -4.731  57.303  1.00 39.08  ?  151 ILE   A H    1 
ATOM   7255  H  HA   . ILE   B 1 152 ? 40.219  -6.961  55.986  1.00 44.52  ?  151 ILE   A HA   1 
ATOM   7256  H  HB   . ILE   B 1 152 ? 40.798  -4.338  55.168  1.00 41.89  ?  151 ILE   A HB   1 
ATOM   7257  H  HG12 . ILE   B 1 152 ? 38.805  -5.889  53.952  1.00 43.28  ?  151 ILE   A HG12 1 
ATOM   7258  H  HG13 . ILE   B 1 152 ? 38.509  -5.440  55.447  1.00 43.28  ?  151 ILE   A HG13 1 
ATOM   7259  H  HG21 . ILE   B 1 152 ? 40.832  -5.224  52.934  1.00 39.55  ?  151 ILE   A HG21 1 
ATOM   7260  H  HG22 . ILE   B 1 152 ? 42.149  -5.441  53.795  1.00 39.55  ?  151 ILE   A HG22 1 
ATOM   7261  H  HG23 . ILE   B 1 152 ? 41.113  -6.631  53.614  1.00 39.55  ?  151 ILE   A HG23 1 
ATOM   7262  H  HD11 . ILE   B 1 152 ? 37.611  -3.988  53.827  1.00 46.52  ?  151 ILE   A HD11 1 
ATOM   7263  H  HD12 . ILE   B 1 152 ? 38.562  -3.263  54.873  1.00 46.52  ?  151 ILE   A HD12 1 
ATOM   7264  H  HD13 . ILE   B 1 152 ? 39.100  -3.611  53.420  1.00 46.52  ?  151 ILE   A HD13 1 
ATOM   7265  N  N    . LEU   B 1 153 ? 43.071  -5.658  56.634  1.00 33.00  ?  152 LEU   A N    1 
ATOM   7266  C  CA   . LEU   B 1 153 ? 44.486  -5.993  56.773  1.00 31.70  ?  152 LEU   A CA   1 
ATOM   7267  C  C    . LEU   B 1 153 ? 44.691  -7.213  57.666  1.00 38.84  ?  152 LEU   A C    1 
ATOM   7268  O  O    . LEU   B 1 153 ? 45.509  -8.083  57.359  1.00 44.11  ?  152 LEU   A O    1 
ATOM   7269  C  CB   . LEU   B 1 153 ? 45.239  -4.796  57.326  1.00 31.37  ?  152 LEU   A CB   1 
ATOM   7270  C  CG   . LEU   B 1 153 ? 45.306  -3.624  56.356  1.00 38.11  ?  152 LEU   A CG   1 
ATOM   7271  C  CD1  . LEU   B 1 153 ? 45.456  -2.296  57.004  1.00 42.76  ?  152 LEU   A CD1  1 
ATOM   7272  C  CD2  . LEU   B 1 153 ? 46.499  -3.906  55.385  1.00 40.12  ?  152 LEU   A CD2  1 
ATOM   7273  H  H    . LEU   B 1 153 ? 42.866  -4.854  56.862  1.00 39.60  ?  152 LEU   A H    1 
ATOM   7274  H  HA   . LEU   B 1 153 ? 44.843  -6.208  55.897  1.00 38.04  ?  152 LEU   A HA   1 
ATOM   7275  H  HB2  . LEU   B 1 153 ? 44.794  -4.492  58.132  1.00 37.65  ?  152 LEU   A HB2  1 
ATOM   7276  H  HB3  . LEU   B 1 153 ? 46.148  -5.066  57.531  1.00 37.65  ?  152 LEU   A HB3  1 
ATOM   7277  H  HG   . LEU   B 1 153 ? 44.462  -3.558  55.883  1.00 45.73  ?  152 LEU   A HG   1 
ATOM   7278  H  HD11 . LEU   B 1 153 ? 45.069  -1.618  56.428  1.00 51.31  ?  152 LEU   A HD11 1 
ATOM   7279  H  HD12 . LEU   B 1 153 ? 44.995  -2.307  57.857  1.00 51.31  ?  152 LEU   A HD12 1 
ATOM   7280  H  HD13 . LEU   B 1 153 ? 46.399  -2.115  57.139  1.00 51.31  ?  152 LEU   A HD13 1 
ATOM   7281  H  HD21 . LEU   B 1 153 ? 46.667  -3.112  54.853  1.00 48.15  ?  152 LEU   A HD21 1 
ATOM   7282  H  HD22 . LEU   B 1 153 ? 47.286  -4.127  55.907  1.00 48.15  ?  152 LEU   A HD22 1 
ATOM   7283  H  HD23 . LEU   B 1 153 ? 46.266  -4.649  54.806  1.00 48.15  ?  152 LEU   A HD23 1 
ATOM   7284  N  N    . ALA   B 1 154 ? 43.940  -7.313  58.768  1.00 41.69  ?  153 ALA   A N    1 
ATOM   7285  C  CA   . ALA   B 1 154 ? 44.139  -8.430  59.689  1.00 39.47  ?  153 ALA   A CA   1 
ATOM   7286  C  C    . ALA   B 1 154 ? 43.643  -9.744  59.096  1.00 40.91  ?  153 ALA   A C    1 
ATOM   7287  O  O    . ALA   B 1 154 ? 44.340  -10.770 59.159  1.00 42.36  ?  153 ALA   A O    1 
ATOM   7288  C  CB   . ALA   B 1 154 ? 43.441  -8.138  61.027  1.00 42.81  ?  153 ALA   A CB   1 
ATOM   7289  H  H    . ALA   B 1 154 ? 43.323  -6.759  58.998  1.00 50.03  ?  153 ALA   A H    1 
ATOM   7290  H  HA   . ALA   B 1 154 ? 45.089  -8.525  59.856  1.00 47.36  ?  153 ALA   A HA   1 
ATOM   7291  H  HB1  . ALA   B 1 154 ? 43.557  -8.900  61.616  1.00 51.37  ?  153 ALA   A HB1  1 
ATOM   7292  H  HB2  . ALA   B 1 154 ? 43.840  -7.348  61.425  1.00 51.37  ?  153 ALA   A HB2  1 
ATOM   7293  H  HB3  . ALA   B 1 154 ? 42.497  -7.986  60.864  1.00 51.37  ?  153 ALA   A HB3  1 
ATOM   7294  N  N    . TYR   B 1 155 ? 42.417  -9.754  58.569  1.00 30.33  ?  154 TYR   A N    1 
ATOM   7295  C  CA   . TYR   B 1 155 ? 41.936  -10.989 57.963  1.00 41.83  ?  154 TYR   A CA   1 
ATOM   7296  C  C    . TYR   B 1 155 ? 42.851  -11.459 56.847  1.00 47.37  ?  154 TYR   A C    1 
ATOM   7297  O  O    . TYR   B 1 155 ? 43.039  -12.672 56.681  1.00 49.82  ?  154 TYR   A O    1 
ATOM   7298  C  CB   . TYR   B 1 155 ? 40.545  -10.802 57.412  1.00 40.18  ?  154 TYR   A CB   1 
ATOM   7299  C  CG   . TYR   B 1 155 ? 39.462  -10.863 58.458  1.00 32.78  ?  154 TYR   A CG   1 
ATOM   7300  C  CD1  . TYR   B 1 155 ? 39.122  -12.061 59.048  1.00 38.21  ?  154 TYR   A CD1  1 
ATOM   7301  C  CD2  . TYR   B 1 155 ? 38.793  -9.744  58.837  1.00 35.74  ?  154 TYR   A CD2  1 
ATOM   7302  C  CE1  . TYR   B 1 155 ? 38.150  -12.151 60.005  1.00 42.25  ?  154 TYR   A CE1  1 
ATOM   7303  C  CE2  . TYR   B 1 155 ? 37.780  -9.808  59.763  1.00 40.77  ?  154 TYR   A CE2  1 
ATOM   7304  C  CZ   . TYR   B 1 155 ? 37.466  -11.026 60.369  1.00 42.52  ?  154 TYR   A CZ   1 
ATOM   7305  O  OH   . TYR   B 1 155 ? 36.468  -11.083 61.324  1.00 36.48  ?  154 TYR   A OH   1 
ATOM   7306  H  H    . TYR   B 1 155 ? 41.871  -9.090  58.552  1.00 36.40  ?  154 TYR   A H    1 
ATOM   7307  H  HA   . TYR   B 1 155 ? 41.908  -11.669 58.654  1.00 50.20  ?  154 TYR   A HA   1 
ATOM   7308  H  HB2  . TYR   B 1 155 ? 40.494  -9.933  56.984  1.00 48.21  ?  154 TYR   A HB2  1 
ATOM   7309  H  HB3  . TYR   B 1 155 ? 40.370  -11.502 56.764  1.00 48.21  ?  154 TYR   A HB3  1 
ATOM   7310  H  HD1  . TYR   B 1 155 ? 39.568  -12.834 58.786  1.00 45.85  ?  154 TYR   A HD1  1 
ATOM   7311  H  HD2  . TYR   B 1 155 ? 39.024  -8.923  58.466  1.00 42.89  ?  154 TYR   A HD2  1 
ATOM   7312  H  HE1  . TYR   B 1 155 ? 37.957  -12.969 60.404  1.00 50.70  ?  154 TYR   A HE1  1 
ATOM   7313  H  HE2  . TYR   B 1 155 ? 37.303  -9.041  59.985  1.00 48.92  ?  154 TYR   A HE2  1 
ATOM   7314  H  HH   . TYR   B 1 155 ? 36.427  -11.856 61.651  1.00 43.77  ?  154 TYR   A HH   1 
ATOM   7315  N  N    . CYS   B 1 156 ? 43.448  -10.522 56.100  1.00 47.38  ?  155 CYS   A N    1 
ATOM   7316  C  CA   . CYS   B 1 156 ? 44.272  -10.854 54.941  1.00 46.11  ?  155 CYS   A CA   1 
ATOM   7317  C  C    . CYS   B 1 156 ? 45.748  -10.990 55.283  1.00 42.69  ?  155 CYS   A C    1 
ATOM   7318  O  O    . CYS   B 1 156 ? 46.569  -11.167 54.378  1.00 52.76  ?  155 CYS   A O    1 
ATOM   7319  C  CB   . CYS   B 1 156 ? 44.118  -9.784  53.848  1.00 46.69  ?  155 CYS   A CB   1 
ATOM   7320  S  SG   . CYS   B 1 156 ? 42.465  -9.465  53.245  1.00 45.48  ?  155 CYS   A SG   1 
ATOM   7321  H  H    . CYS   B 1 156 ? 43.388  -9.677  56.249  1.00 56.86  ?  155 CYS   A H    1 
ATOM   7322  H  HA   . CYS   B 1 156 ? 43.959  -11.700 54.586  1.00 55.33  ?  155 CYS   A HA   1 
ATOM   7323  H  HB2  . CYS   B 1 156 ? 44.456  -8.946  54.200  1.00 56.03  ?  155 CYS   A HB2  1 
ATOM   7324  H  HB3  . CYS   B 1 156 ? 44.647  -10.061 53.083  1.00 56.03  ?  155 CYS   A HB3  1 
ATOM   7325  H  HG   . CYS   B 1 156 ? 42.469  -8.444  52.615  1.00 54.57  ?  155 CYS   A HG   1 
ATOM   7326  N  N    . ASN   B 1 157 ? 46.113  -10.825 56.548  1.00 44.82  ?  156 ASN   A N    1 
ATOM   7327  C  CA   . ASN   B 1 157 ? 47.478  -11.011 57.002  1.00 37.95  ?  156 ASN   A CA   1 
ATOM   7328  C  C    . ASN   B 1 157 ? 48.447  -10.083 56.283  1.00 40.88  ?  156 ASN   A C    1 
ATOM   7329  O  O    . ASN   B 1 157 ? 49.586  -10.452 56.001  1.00 36.46  ?  156 ASN   A O    1 
ATOM   7330  C  CB   . ASN   B 1 157 ? 47.921  -12.451 56.822  1.00 42.51  ?  156 ASN   A CB   1 
ATOM   7331  C  CG   . ASN   B 1 157 ? 47.753  -13.263 58.077  1.00 57.56  ?  156 ASN   A CG   1 
ATOM   7332  O  OD1  . ASN   B 1 157 ? 48.562  -13.180 59.007  1.00 54.94  ?  156 ASN   A OD1  1 
ATOM   7333  N  ND2  . ASN   B 1 157 ? 46.665  -14.042 58.132  1.00 55.19  ?  156 ASN   A ND2  1 
ATOM   7334  H  H    . ASN   B 1 157 ? 45.572  -10.600 57.177  1.00 53.79  ?  156 ASN   A H    1 
ATOM   7335  H  HA   . ASN   B 1 157 ? 47.504  -10.788 57.946  1.00 45.54  ?  156 ASN   A HA   1 
ATOM   7336  H  HB2  . ASN   B 1 157 ? 47.389  -12.862 56.123  1.00 51.02  ?  156 ASN   A HB2  1 
ATOM   7337  H  HB3  . ASN   B 1 157 ? 48.860  -12.467 56.577  1.00 51.02  ?  156 ASN   A HB3  1 
ATOM   7338  H  HD21 . ASN   B 1 157 ? 46.113  -14.057 57.472  1.00 66.22  ?  156 ASN   A HD21 1 
ATOM   7339  H  HD22 . ASN   B 1 157 ? 46.518  -14.528 58.826  1.00 66.22  ?  156 ASN   A HD22 1 
ATOM   7340  N  N    . LYS   B 1 158 ? 48.002  -8.871  55.997  1.00 40.17  ?  157 LYS   A N    1 
ATOM   7341  C  CA   . LYS   B 1 158 ? 48.838  -7.849  55.404  1.00 41.75  ?  157 LYS   A CA   1 
ATOM   7342  C  C    . LYS   B 1 158 ? 49.125  -6.762  56.430  1.00 35.47  ?  157 LYS   A C    1 
ATOM   7343  O  O    . LYS   B 1 158 ? 48.300  -6.480  57.307  1.00 41.65  ?  157 LYS   A O    1 
ATOM   7344  C  CB   . LYS   B 1 158 ? 48.164  -7.252  54.157  1.00 41.54  ?  157 LYS   A CB   1 
ATOM   7345  C  CG   . LYS   B 1 158 ? 48.279  -8.194  52.950  1.00 48.58  ?  157 LYS   A CG   1 
ATOM   7346  C  CD   . LYS   B 1 158 ? 48.708  -7.510  51.664  1.00 51.31  ?  157 LYS   A CD   1 
ATOM   7347  C  CE   . LYS   B 1 158 ? 49.024  -8.583  50.603  1.00 57.39  ?  157 LYS   A CE   1 
ATOM   7348  N  NZ   . LYS   B 1 158 ? 50.304  -8.355  49.838  1.00 54.64  ?  157 LYS   A NZ   1 
ATOM   7349  H  H    . LYS   B 1 158 ? 47.195  -8.612  56.142  1.00 48.20  ?  157 LYS   A H    1 
ATOM   7350  H  HA   . LYS   B 1 158 ? 49.687  -8.227  55.128  1.00 50.10  ?  157 LYS   A HA   1 
ATOM   7351  H  HB2  . LYS   B 1 158 ? 47.223  -7.104  54.341  1.00 49.85  ?  157 LYS   A HB2  1 
ATOM   7352  H  HB3  . LYS   B 1 158 ? 48.594  -6.412  53.931  1.00 49.85  ?  157 LYS   A HB3  1 
ATOM   7353  H  HG2  . LYS   B 1 158 ? 48.936  -8.878  53.152  1.00 58.30  ?  157 LYS   A HG2  1 
ATOM   7354  H  HG3  . LYS   B 1 158 ? 47.413  -8.602  52.791  1.00 58.30  ?  157 LYS   A HG3  1 
ATOM   7355  H  HD2  . LYS   B 1 158 ? 47.992  -6.944  51.335  1.00 61.57  ?  157 LYS   A HD2  1 
ATOM   7356  H  HD3  . LYS   B 1 158 ? 49.504  -6.979  51.821  1.00 61.57  ?  157 LYS   A HD3  1 
ATOM   7357  H  HE2  . LYS   B 1 158 ? 49.099  -9.443  51.047  1.00 68.87  ?  157 LYS   A HE2  1 
ATOM   7358  H  HE3  . LYS   B 1 158 ? 48.299  -8.604  49.959  1.00 68.87  ?  157 LYS   A HE3  1 
ATOM   7359  H  HZ1  . LYS   B 1 158 ? 50.517  -9.085  49.377  1.00 65.56  ?  157 LYS   A HZ1  1 
ATOM   7360  H  HZ2  . LYS   B 1 158 ? 50.203  -7.675  49.272  1.00 65.56  ?  157 LYS   A HZ2  1 
ATOM   7361  H  HZ3  . LYS   B 1 158 ? 50.966  -8.165  50.402  1.00 65.56  ?  157 LYS   A HZ3  1 
ATOM   7362  N  N    . THR   B 1 159 ? 50.287  -6.136  56.284  1.00 35.68  ?  158 THR   A N    1 
ATOM   7363  C  CA   . THR   B 1 159 ? 50.703  -5.029  57.127  1.00 43.80  ?  158 THR   A CA   1 
ATOM   7364  C  C    . THR   B 1 159 ? 50.519  -3.697  56.412  1.00 41.35  ?  158 THR   A C    1 
ATOM   7365  O  O    . THR   B 1 159 ? 50.468  -3.621  55.180  1.00 40.25  ?  158 THR   A O    1 
ATOM   7366  C  CB   . THR   B 1 159 ? 52.177  -5.171  57.545  1.00 44.03  ?  158 THR   A CB   1 
ATOM   7367  O  OG1  . THR   B 1 159 ? 52.983  -5.485  56.398  1.00 48.06  ?  158 THR   A OG1  1 
ATOM   7368  C  CG2  . THR   B 1 159 ? 52.351  -6.264  58.614  1.00 41.98  ?  158 THR   A CG2  1 
ATOM   7369  H  H    . THR   B 1 159 ? 50.868  -6.343  55.685  1.00 42.82  ?  158 THR   A H    1 
ATOM   7370  H  HA   . THR   B 1 159 ? 50.150  -5.034  57.924  1.00 52.56  ?  158 THR   A HA   1 
ATOM   7371  H  HB   . THR   B 1 159 ? 52.478  -4.332  57.928  1.00 52.83  ?  158 THR   A HB   1 
ATOM   7372  H  HG1  . THR   B 1 159 ? 53.767  -5.666  56.639  1.00 57.68  ?  158 THR   A HG1  1 
ATOM   7373  H  HG21 . THR   B 1 159 ? 53.227  -6.192  59.024  1.00 50.37  ?  158 THR   A HG21 1 
ATOM   7374  H  HG22 . THR   B 1 159 ? 51.673  -6.167  59.301  1.00 50.37  ?  158 THR   A HG22 1 
ATOM   7375  H  HG23 . THR   B 1 159 ? 52.265  -7.141  58.209  1.00 50.37  ?  158 THR   A HG23 1 
ATOM   7376  N  N    . VAL   B 1 160 ? 50.439  -2.634  57.223  1.00 41.73  ?  159 VAL   A N    1 
ATOM   7377  C  CA   . VAL   B 1 160 ? 50.396  -1.287  56.679  1.00 45.10  ?  159 VAL   A CA   1 
ATOM   7378  C  C    . VAL   B 1 160 ? 51.672  -1.032  55.903  1.00 43.74  ?  159 VAL   A C    1 
ATOM   7379  O  O    . VAL   B 1 160 ? 52.766  -1.476  56.290  1.00 35.96  ?  159 VAL   A O    1 
ATOM   7380  C  CB   . VAL   B 1 160 ? 50.200  -0.254  57.800  1.00 45.43  ?  159 VAL   A CB   1 
ATOM   7381  C  CG1  . VAL   B 1 160 ? 50.015  1.161   57.249  1.00 43.65  ?  159 VAL   A CG1  1 
ATOM   7382  C  CG2  . VAL   B 1 160 ? 49.008  -0.645  58.593  1.00 46.54  ?  159 VAL   A CG2  1 
ATOM   7383  H  H    . VAL   B 1 160 ? 50.408  -2.673  58.081  1.00 50.08  ?  159 VAL   A H    1 
ATOM   7384  H  HA   . VAL   B 1 160 ? 49.641  -1.206  56.076  1.00 54.12  ?  159 VAL   A HA   1 
ATOM   7385  H  HB   . VAL   B 1 160 ? 50.993  -0.239  58.359  1.00 54.52  ?  159 VAL   A HB   1 
ATOM   7386  H  HG11 . VAL   B 1 160 ? 49.934  1.781   57.991  1.00 52.38  ?  159 VAL   A HG11 1 
ATOM   7387  H  HG12 . VAL   B 1 160 ? 50.786  1.392   56.707  1.00 52.38  ?  159 VAL   A HG12 1 
ATOM   7388  H  HG13 . VAL   B 1 160 ? 49.210  1.187   56.708  1.00 52.38  ?  159 VAL   A HG13 1 
ATOM   7389  H  HG21 . VAL   B 1 160 ? 48.726  0.109   59.133  1.00 55.85  ?  159 VAL   A HG21 1 
ATOM   7390  H  HG22 . VAL   B 1 160 ? 48.296  -0.902  57.987  1.00 55.85  ?  159 VAL   A HG22 1 
ATOM   7391  H  HG23 . VAL   B 1 160 ? 49.241  -1.393  59.165  1.00 55.85  ?  159 VAL   A HG23 1 
ATOM   7392  N  N    . GLY   B 1 161 ? 51.527  -0.338  54.772  1.00 36.93  ?  160 GLY   A N    1 
ATOM   7393  C  CA   . GLY   B 1 161 ? 52.665  -0.029  53.934  1.00 37.47  ?  160 GLY   A CA   1 
ATOM   7394  C  C    . GLY   B 1 161 ? 52.915  -1.017  52.827  1.00 35.78  ?  160 GLY   A C    1 
ATOM   7395  O  O    . GLY   B 1 161 ? 53.681  -0.707  51.903  1.00 35.99  ?  160 GLY   A O    1 
ATOM   7396  H  H    . GLY   B 1 161 ? 50.777  -0.039  54.477  1.00 44.32  ?  160 GLY   A H    1 
ATOM   7397  H  HA2  . GLY   B 1 161 ? 52.527  0.842   53.530  1.00 44.96  ?  160 GLY   A HA2  1 
ATOM   7398  H  HA3  . GLY   B 1 161 ? 53.460  0.003   54.488  1.00 44.96  ?  160 GLY   A HA3  1 
ATOM   7399  N  N    . GLU   B 1 162 ? 52.259  -2.168  52.857  1.00 36.88  ?  161 GLU   A N    1 
ATOM   7400  C  CA   . GLU   B 1 162 ? 52.429  -3.203  51.847  1.00 40.16  ?  161 GLU   A CA   1 
ATOM   7401  C  C    . GLU   B 1 162 ? 51.299  -3.123  50.820  1.00 36.54  ?  161 GLU   A C    1 
ATOM   7402  O  O    . GLU   B 1 162 ? 50.122  -3.120  51.186  1.00 36.25  ?  161 GLU   A O    1 
ATOM   7403  C  CB   . GLU   B 1 162 ? 52.440  -4.563  52.536  1.00 38.00  ?  161 GLU   A CB   1 
ATOM   7404  C  CG   . GLU   B 1 162 ? 52.802  -5.744  51.707  1.00 45.65  ?  161 GLU   A CG   1 
ATOM   7405  C  CD   . GLU   B 1 162 ? 52.564  -7.042  52.504  1.00 55.32  ?  161 GLU   A CD   1 
ATOM   7406  O  OE1  . GLU   B 1 162 ? 52.532  -8.117  51.838  1.00 55.88  ?  161 GLU   A OE1  1 
ATOM   7407  O  OE2  . GLU   B 1 162 ? 52.402  -6.970  53.781  1.00 51.53  ?  161 GLU   A OE2  1 
ATOM   7408  H  H    . GLU   B 1 162 ? 51.695  -2.379  53.470  1.00 44.26  ?  161 GLU   A H    1 
ATOM   7409  H  HA   . GLU   B 1 162 ? 53.260  -3.077  51.364  1.00 48.20  ?  161 GLU   A HA   1 
ATOM   7410  H  HB2  . GLU   B 1 162 ? 53.080  -4.523  53.264  1.00 45.61  ?  161 GLU   A HB2  1 
ATOM   7411  H  HB3  . GLU   B 1 162 ? 51.550  -4.728  52.885  1.00 45.61  ?  161 GLU   A HB3  1 
ATOM   7412  H  HG2  . GLU   B 1 162 ? 52.253  -5.763  50.908  1.00 54.78  ?  161 GLU   A HG2  1 
ATOM   7413  H  HG3  . GLU   B 1 162 ? 53.740  -5.696  51.464  1.00 54.78  ?  161 GLU   A HG3  1 
ATOM   7414  N  N    . LEU   B 1 163 ? 51.650  -3.075  49.538  1.00 29.95  ?  162 LEU   A N    1 
ATOM   7415  C  CA   . LEU   B 1 163 ? 50.634  -3.071  48.484  1.00 32.56  ?  162 LEU   A CA   1 
ATOM   7416  C  C    . LEU   B 1 163 ? 50.062  -4.473  48.259  1.00 31.24  ?  162 LEU   A C    1 
ATOM   7417  O  O    . LEU   B 1 163 ? 50.800  -5.438  48.021  1.00 34.26  ?  162 LEU   A O    1 
ATOM   7418  C  CB   . LEU   B 1 163 ? 51.227  -2.539  47.182  1.00 34.46  ?  162 LEU   A CB   1 
ATOM   7419  C  CG   . LEU   B 1 163 ? 50.261  -2.351  46.024  1.00 27.62  ?  162 LEU   A CG   1 
ATOM   7420  C  CD1  . LEU   B 1 163 ? 49.441  -1.088  46.134  1.00 32.67  ?  162 LEU   A CD1  1 
ATOM   7421  C  CD2  . LEU   B 1 163 ? 51.068  -2.313  44.737  1.00 33.28  ?  162 LEU   A CD2  1 
ATOM   7422  H  H    . LEU   B 1 163 ? 52.461  -3.043  49.253  1.00 35.95  ?  162 LEU   A H    1 
ATOM   7423  H  HA   . LEU   B 1 163 ? 49.905  -2.493  48.759  1.00 39.07  ?  162 LEU   A HA   1 
ATOM   7424  H  HB2  . LEU   B 1 163 ? 51.624  -1.674  47.365  1.00 41.36  ?  162 LEU   A HB2  1 
ATOM   7425  H  HB3  . LEU   B 1 163 ? 51.909  -3.162  46.886  1.00 41.36  ?  162 LEU   A HB3  1 
ATOM   7426  H  HG   . LEU   B 1 163 ? 49.630  -3.088  46.028  1.00 33.15  ?  162 LEU   A HG   1 
ATOM   7427  H  HD11 . LEU   B 1 163 ? 49.020  -0.908  45.279  1.00 39.21  ?  162 LEU   A HD11 1 
ATOM   7428  H  HD12 . LEU   B 1 163 ? 48.764  -1.209  46.817  1.00 39.21  ?  162 LEU   A HD12 1 
ATOM   7429  H  HD13 . LEU   B 1 163 ? 50.026  -0.352  46.376  1.00 39.21  ?  162 LEU   A HD13 1 
ATOM   7430  H  HD21 . LEU   B 1 163 ? 50.461  -2.213  43.987  1.00 39.93  ?  162 LEU   A HD21 1 
ATOM   7431  H  HD22 . LEU   B 1 163 ? 51.679  -1.560  44.770  1.00 39.93  ?  162 LEU   A HD22 1 
ATOM   7432  H  HD23 . LEU   B 1 163 ? 51.566  -3.141  44.652  1.00 39.93  ?  162 LEU   A HD23 1 
ATOM   7433  N  N    . GLY   B 1 164 ? 48.735  -4.586  48.339  1.00 29.68  ?  163 GLY   A N    1 
ATOM   7434  C  CA   . GLY   B 1 164 ? 48.048  -5.841  48.155  1.00 29.40  ?  163 GLY   A CA   1 
ATOM   7435  C  C    . GLY   B 1 164 ? 47.308  -5.879  46.823  1.00 27.01  ?  163 GLY   A C    1 
ATOM   7436  O  O    . GLY   B 1 164 ? 47.168  -4.881  46.131  1.00 27.03  ?  163 GLY   A O    1 
ATOM   7437  H  H    . GLY   B 1 164 ? 48.208  -3.927  48.503  1.00 35.62  ?  163 GLY   A H    1 
ATOM   7438  H  HA2  . GLY   B 1 164 ? 48.689  -6.569  48.174  1.00 35.28  ?  163 GLY   A HA2  1 
ATOM   7439  H  HA3  . GLY   B 1 164 ? 47.405  -5.968  48.871  1.00 35.28  ?  163 GLY   A HA3  1 
ATOM   7440  N  N    . ASP   B 1 165 ? 46.818  -7.069  46.484  1.00 26.42  ?  164 ASP   A N    1 
ATOM   7441  C  CA   . ASP   B 1 165 ? 46.131  -7.332  45.230  1.00 27.32  ?  164 ASP   A CA   1 
ATOM   7442  C  C    . ASP   B 1 165 ? 44.617  -7.344  45.468  1.00 33.77  ?  164 ASP   A C    1 
ATOM   7443  O  O    . ASP   B 1 165 ? 44.110  -8.004  46.396  1.00 29.55  ?  164 ASP   A O    1 
ATOM   7444  C  CB   . ASP   B 1 165 ? 46.641  -8.644  44.657  1.00 24.27  ?  164 ASP   A CB   1 
ATOM   7445  C  CG   . ASP   B 1 165 ? 45.898  -9.071  43.419  1.00 34.45  ?  164 ASP   A CG   1 
ATOM   7446  O  OD1  . ASP   B 1 165 ? 44.674  -9.049  43.442  1.00 36.85  ?  164 ASP   A OD1  1 
ATOM   7447  O  OD2  . ASP   B 1 165 ? 46.523  -9.401  42.388  1.00 35.26  ?  164 ASP   A OD2  1 
ATOM   7448  H  H    . ASP   B 1 165 ? 46.875  -7.765  46.986  1.00 31.70  ?  164 ASP   A H    1 
ATOM   7449  H  HA   . ASP   B 1 165 ? 46.297  -6.633  44.578  1.00 32.79  ?  164 ASP   A HA   1 
ATOM   7450  H  HB2  . ASP   B 1 165 ? 47.578  -8.544  44.425  1.00 29.12  ?  164 ASP   A HB2  1 
ATOM   7451  H  HB3  . ASP   B 1 165 ? 46.538  -9.341  45.324  1.00 29.12  ?  164 ASP   A HB3  1 
ATOM   7452  N  N    . VAL   B 1 166 ? 43.899  -6.587  44.634  1.00 33.88  ?  165 VAL   A N    1 
ATOM   7453  C  CA   . VAL   B 1 166 ? 42.487  -6.347  44.899  1.00 29.80  ?  165 VAL   A CA   1 
ATOM   7454  C  C    . VAL   B 1 166 ? 41.674  -7.624  44.745  1.00 28.38  ?  165 VAL   A C    1 
ATOM   7455  O  O    . VAL   B 1 166 ? 40.849  -7.956  45.606  1.00 23.66  ?  165 VAL   A O    1 
ATOM   7456  C  CB   . VAL   B 1 166 ? 41.955  -5.237  43.985  1.00 30.66  ?  165 VAL   A CB   1 
ATOM   7457  C  CG1  . VAL   B 1 166 ? 40.476  -5.337  43.917  1.00 28.26  ?  165 VAL   A CG1  1 
ATOM   7458  C  CG2  . VAL   B 1 166 ? 42.395  -3.848  44.487  1.00 32.90  ?  165 VAL   A CG2  1 
ATOM   7459  H  H    . VAL   B 1 166 ? 44.202  -6.210  43.923  1.00 40.65  ?  165 VAL   A H    1 
ATOM   7460  H  HA   . VAL   B 1 166 ? 42.402  -6.055  45.820  1.00 35.76  ?  165 VAL   A HA   1 
ATOM   7461  H  HB   . VAL   B 1 166 ? 42.322  -5.344  43.094  1.00 36.80  ?  165 VAL   A HB   1 
ATOM   7462  H  HG11 . VAL   B 1 166 ? 40.118  -4.497  43.589  1.00 33.91  ?  165 VAL   A HG11 1 
ATOM   7463  H  HG12 . VAL   B 1 166 ? 40.236  -6.057  43.313  1.00 33.91  ?  165 VAL   A HG12 1 
ATOM   7464  H  HG13 . VAL   B 1 166 ? 40.130  -5.520  44.804  1.00 33.91  ?  165 VAL   A HG13 1 
ATOM   7465  H  HG21 . VAL   B 1 166 ? 41.932  -3.166  43.976  1.00 39.48  ?  165 VAL   A HG21 1 
ATOM   7466  H  HG22 . VAL   B 1 166 ? 42.171  -3.766  45.427  1.00 39.48  ?  165 VAL   A HG22 1 
ATOM   7467  H  HG23 . VAL   B 1 166 ? 43.353  -3.757  44.366  1.00 39.48  ?  165 VAL   A HG23 1 
ATOM   7468  N  N    . ARG   B 1 167 ? 41.897  -8.357  43.656  1.00 28.50  ?  166 ARG   A N    1 
ATOM   7469  C  CA   . ARG   B 1 167 ? 41.255  -9.651  43.489  1.00 30.40  ?  166 ARG   A CA   1 
ATOM   7470  C  C    . ARG   B 1 167 ? 41.506  -10.568 44.687  1.00 30.64  ?  166 ARG   A C    1 
ATOM   7471  O  O    . ARG   B 1 167 ? 40.575  -11.144 45.242  1.00 30.06  ?  166 ARG   A O    1 
ATOM   7472  C  CB   . ARG   B 1 167 ? 41.739  -10.291 42.192  1.00 34.08  ?  166 ARG   A CB   1 
ATOM   7473  C  CG   . ARG   B 1 167 ? 40.942  -11.531 41.779  1.00 29.45  ?  166 ARG   A CG   1 
ATOM   7474  C  CD   . ARG   B 1 167 ? 41.463  -12.101 40.463  1.00 34.06  ?  166 ARG   A CD   1 
ATOM   7475  N  NE   . ARG   B 1 167 ? 42.894  -12.376 40.547  1.00 37.94  ?  166 ARG   A NE   1 
ATOM   7476  C  CZ   . ARG   B 1 167 ? 43.384  -13.574 40.833  1.00 37.94  ?  166 ARG   A CZ   1 
ATOM   7477  N  NH1  . ARG   B 1 167 ? 42.581  -14.592 41.094  1.00 38.47  ?  166 ARG   A NH1  1 
ATOM   7478  N  NH2  . ARG   B 1 167 ? 44.710  -13.768 40.817  1.00 43.24  ?  166 ARG   A NH2  1 
ATOM   7479  H  H    . ARG   B 1 167 ? 42.412  -8.128  43.007  1.00 34.20  ?  166 ARG   A H    1 
ATOM   7480  H  HA   . ARG   B 1 167 ? 40.296  -9.522  43.426  1.00 36.48  ?  166 ARG   A HA   1 
ATOM   7481  H  HB2  . ARG   B 1 167 ? 41.664  -9.640  41.477  1.00 40.89  ?  166 ARG   A HB2  1 
ATOM   7482  H  HB3  . ARG   B 1 167 ? 42.665  -10.557 42.302  1.00 40.89  ?  166 ARG   A HB3  1 
ATOM   7483  H  HG2  . ARG   B 1 167 ? 41.028  -12.213 42.464  1.00 35.34  ?  166 ARG   A HG2  1 
ATOM   7484  H  HG3  . ARG   B 1 167 ? 40.009  -11.293 41.663  1.00 35.34  ?  166 ARG   A HG3  1 
ATOM   7485  H  HD2  . ARG   B 1 167 ? 41.001  -12.930 40.264  1.00 40.87  ?  166 ARG   A HD2  1 
ATOM   7486  H  HD3  . ARG   B 1 167 ? 41.314  -11.459 39.751  1.00 40.87  ?  166 ARG   A HD3  1 
ATOM   7487  H  HE   . ARG   B 1 167 ? 43.445  -11.732 40.403  1.00 45.53  ?  166 ARG   A HE   1 
ATOM   7488  H  HH11 . ARG   B 1 167 ? 41.728  -14.482 41.079  1.00 46.17  ?  166 ARG   A HH11 1 
ATOM   7489  H  HH12 . ARG   B 1 167 ? 42.912  -15.364 41.278  1.00 46.17  ?  166 ARG   A HH12 1 
ATOM   7490  H  HH21 . ARG   B 1 167 ? 45.237  -13.118 40.622  1.00 51.89  ?  166 ARG   A HH21 1 
ATOM   7491  H  HH22 . ARG   B 1 167 ? 45.033  -14.543 41.002  1.00 51.89  ?  166 ARG   A HH22 1 
ATOM   7492  N  N    . GLU   B 1 168 ? 42.758  -10.732 45.112  1.00 33.15  ?  167 GLU   A N    1 
ATOM   7493  C  CA   . GLU   B 1 168 ? 43.011  -11.654 46.232  1.00 38.10  ?  167 GLU   A CA   1 
ATOM   7494  C  C    . GLU   B 1 168 ? 42.341  -11.129 47.506  1.00 33.24  ?  167 GLU   A C    1 
ATOM   7495  O  O    . GLU   B 1 168 ? 41.718  -11.886 48.273  1.00 33.23  ?  167 GLU   A O    1 
ATOM   7496  C  CB   . GLU   B 1 168 ? 44.534  -11.878 46.436  1.00 37.29  ?  167 GLU   A CB   1 
ATOM   7497  C  CG   . GLU   B 1 168 ? 45.221  -12.327 45.142  1.00 47.26  ?  167 GLU   A CG   1 
ATOM   7498  C  CD   . GLU   B 1 168 ? 46.610  -12.968 45.336  1.00 50.50  ?  167 GLU   A CD   1 
ATOM   7499  O  OE1  . GLU   B 1 168 ? 47.173  -13.450 44.307  1.00 46.65  ?  167 GLU   A OE1  1 
ATOM   7500  O  OE2  . GLU   B 1 168 ? 47.128  -12.983 46.489  1.00 46.61  ?  167 GLU   A OE2  1 
ATOM   7501  H  H    . GLU   B 1 168 ? 43.452  -10.342 44.787  1.00 39.78  ?  167 GLU   A H    1 
ATOM   7502  H  HA   . GLU   B 1 168 ? 42.636  -12.524 46.023  1.00 45.72  ?  167 GLU   A HA   1 
ATOM   7503  H  HB2  . GLU   B 1 168 ? 44.943  -11.047 46.725  1.00 44.75  ?  167 GLU   A HB2  1 
ATOM   7504  H  HB3  . GLU   B 1 168 ? 44.669  -12.566 47.106  1.00 44.75  ?  167 GLU   A HB3  1 
ATOM   7505  H  HG2  . GLU   B 1 168 ? 44.656  -12.983 44.704  1.00 56.71  ?  167 GLU   A HG2  1 
ATOM   7506  H  HG3  . GLU   B 1 168 ? 45.335  -11.552 44.569  1.00 56.71  ?  167 GLU   A HG3  1 
ATOM   7507  N  N    . THR   B 1 169 ? 42.377  -9.820  47.691  1.00 30.22  ?  168 THR   A N    1 
ATOM   7508  C  CA   . THR   B 1 169 ? 41.737  -9.159  48.808  1.00 29.57  ?  168 THR   A CA   1 
ATOM   7509  C  C    . THR   B 1 169 ? 40.243  -9.422  48.797  1.00 35.37  ?  168 THR   A C    1 
ATOM   7510  O  O    . THR   B 1 169 ? 39.694  -9.801  49.790  1.00 33.92  ?  168 THR   A O    1 
ATOM   7511  C  CB   . THR   B 1 169 ? 41.982  -7.636  48.798  1.00 33.97  ?  168 THR   A CB   1 
ATOM   7512  O  OG1  . THR   B 1 169 ? 43.369  -7.366  48.733  1.00 31.37  ?  168 THR   A OG1  1 
ATOM   7513  C  CG2  . THR   B 1 169 ? 41.456  -6.995  50.005  1.00 30.58  ?  168 THR   A CG2  1 
ATOM   7514  H  H    . THR   B 1 169 ? 42.783  -9.276  47.163  1.00 36.26  ?  168 THR   A H    1 
ATOM   7515  H  HA   . THR   B 1 169 ? 42.103  -9.519  49.643  1.00 35.49  ?  168 THR   A HA   1 
ATOM   7516  H  HB   . THR   B 1 169 ? 41.543  -7.245  48.027  1.00 40.77  ?  168 THR   A HB   1 
ATOM   7517  H  HG1  . THR   B 1 169 ? 43.650  -7.162  49.476  1.00 37.65  ?  168 THR   A HG1  1 
ATOM   7518  H  HG21 . THR   B 1 169 ? 42.180  -6.687  50.555  1.00 36.70  ?  168 THR   A HG21 1 
ATOM   7519  H  HG22 . THR   B 1 169 ? 40.907  -6.245  49.764  1.00 36.70  ?  168 THR   A HG22 1 
ATOM   7520  H  HG23 . THR   B 1 169 ? 40.928  -7.621  50.506  1.00 36.70  ?  168 THR   A HG23 1 
ATOM   7521  N  N    . MET   B 1 170 ? 39.599  -9.256  47.652  1.00 34.89  ?  169 MET   A N    1 
ATOM   7522  C  CA   . MET   B 1 170 ? 38.190  -9.514  47.532  1.00 33.09  ?  169 MET   A CA   1 
ATOM   7523  C  C    . MET   B 1 170 ? 37.925  -10.968 47.761  1.00 34.84  ?  169 MET   A C    1 
ATOM   7524  O  O    . MET   B 1 170 ? 36.957  -11.268 48.369  1.00 29.22  ?  169 MET   A O    1 
ATOM   7525  C  CB   . MET   B 1 170 ? 37.634  -9.138  46.177  1.00 35.19  ?  169 MET   A CB   1 
ATOM   7526  C  CG   . MET   B 1 170 ? 37.647  -7.681  45.785  1.00 42.70  ?  169 MET   A CG   1 
ATOM   7527  S  SD   . MET   B 1 170 ? 36.548  -6.629  46.664  1.00 46.59  ?  169 MET   A SD   1 
ATOM   7528  C  CE   . MET   B 1 170 ? 37.361  -6.661  48.191  1.00 39.37  ?  169 MET   A CE   1 
ATOM   7529  H  H    . MET   B 1 170 ? 39.969  -8.989  46.923  1.00 41.86  ?  169 MET   A H    1 
ATOM   7530  H  HA   . MET   B 1 170 ? 37.706  -9.054  48.236  1.00 39.71  ?  169 MET   A HA   1 
ATOM   7531  H  HB2  . MET   B 1 170 ? 38.142  -9.616  45.502  1.00 42.22  ?  169 MET   A HB2  1 
ATOM   7532  H  HB3  . MET   B 1 170 ? 36.710  -9.431  46.143  1.00 42.22  ?  169 MET   A HB3  1 
ATOM   7533  H  HG2  . MET   B 1 170 ? 38.544  -7.337  45.917  1.00 51.25  ?  169 MET   A HG2  1 
ATOM   7534  H  HG3  . MET   B 1 170 ? 37.414  -7.618  44.845  1.00 51.25  ?  169 MET   A HG3  1 
ATOM   7535  H  HE1  . MET   B 1 170 ? 37.255  -7.529  48.585  1.00 47.24  ?  169 MET   A HE1  1 
ATOM   7536  H  HE2  . MET   B 1 170 ? 38.292  -6.471  48.057  1.00 47.24  ?  169 MET   A HE2  1 
ATOM   7537  H  HE3  . MET   B 1 170 ? 36.969  -5.998  48.764  1.00 47.24  ?  169 MET   A HE3  1 
ATOM   7538  N  N    . SER   B 1 171 ? 38.767  -11.842 47.226  1.00 26.71  ?  170 SER   A N    1 
ATOM   7539  C  CA   . SER   B 1 171 ? 38.658  -13.269 47.448  1.00 39.29  ?  170 SER   A CA   1 
ATOM   7540  C  C    . SER   B 1 171 ? 38.515  -13.558 48.891  1.00 39.18  ?  170 SER   A C    1 
ATOM   7541  O  O    . SER   B 1 171 ? 37.593  -14.139 49.263  1.00 36.75  ?  170 SER   A O    1 
ATOM   7542  C  CB   . SER   B 1 171 ? 39.887  -14.095 47.012  1.00 34.02  ?  170 SER   A CB   1 
ATOM   7543  O  OG   . SER   B 1 171 ? 39.468  -15.404 46.912  1.00 43.60  ?  170 SER   A OG   1 
ATOM   7544  H  H    . SER   B 1 171 ? 39.427  -11.627 46.718  1.00 32.06  ?  170 SER   A H    1 
ATOM   7545  H  HA   . SER   B 1 171 ? 37.868  -13.615 46.980  1.00 47.14  ?  170 SER   A HA   1 
ATOM   7546  H  HB2  . SER   B 1 171 ? 40.131  -13.782 46.129  1.00 40.82  ?  170 SER   A HB2  1 
ATOM   7547  H  HB3  . SER   B 1 171 ? 40.708  -14.062 47.526  1.00 40.82  ?  170 SER   A HB3  1 
ATOM   7548  H  HG   . SER   B 1 171 ? 39.192  -15.667 47.637  1.00 52.32  ?  170 SER   A HG   1 
ATOM   7549  N  N    . TYR   B 1 172 ? 39.418  -13.032 49.677  1.00 37.98  ?  171 TYR   A N    1 
ATOM   7550  C  CA   . TYR   B 1 172 ? 39.486  -13.309 51.107  1.00 43.51  ?  171 TYR   A CA   1 
ATOM   7551  C  C    . TYR   B 1 172 ? 38.184  -12.896 51.780  1.00 39.54  ?  171 TYR   A C    1 
ATOM   7552  O  O    . TYR   B 1 172 ? 37.566  -13.684 52.507  1.00 40.48  ?  171 TYR   A O    1 
ATOM   7553  C  CB   . TYR   B 1 172 ? 40.659  -12.562 51.751  1.00 39.31  ?  171 TYR   A CB   1 
ATOM   7554  C  CG   . TYR   B 1 172 ? 41.975  -13.330 51.881  1.00 67.62  ?  171 TYR   A CG   1 
ATOM   7555  C  CD1  . TYR   B 1 172 ? 42.009  -14.636 52.365  1.00 70.91  ?  171 TYR   A CD1  1 
ATOM   7556  C  CD2  . TYR   B 1 172 ? 43.210  -12.711 51.557  1.00 68.90  ?  171 TYR   A CD2  1 
ATOM   7557  C  CE1  . TYR   B 1 172 ? 43.221  -15.311 52.507  1.00 71.54  ?  171 TYR   A CE1  1 
ATOM   7558  C  CE2  . TYR   B 1 172 ? 44.426  -13.382 51.702  1.00 63.17  ?  171 TYR   A CE2  1 
ATOM   7559  C  CZ   . TYR   B 1 172 ? 44.424  -14.676 52.182  1.00 73.91  ?  171 TYR   A CZ   1 
ATOM   7560  O  OH   . TYR   B 1 172 ? 45.628  -15.338 52.329  1.00 77.71  ?  171 TYR   A OH   1 
ATOM   7561  H  H    . TYR   B 1 172 ? 39.994  -12.461 49.389  1.00 45.57  ?  171 TYR   A H    1 
ATOM   7562  H  HA   . TYR   B 1 172 ? 39.633  -14.260 51.231  1.00 52.21  ?  171 TYR   A HA   1 
ATOM   7563  H  HB2  . TYR   B 1 172 ? 40.843  -11.773 51.217  1.00 47.17  ?  171 TYR   A HB2  1 
ATOM   7564  H  HB3  . TYR   B 1 172 ? 40.393  -12.302 52.647  1.00 47.17  ?  171 TYR   A HB3  1 
ATOM   7565  H  HD1  . TYR   B 1 172 ? 41.215  -15.062 52.595  1.00 85.09  ?  171 TYR   A HD1  1 
ATOM   7566  H  HD2  . TYR   B 1 172 ? 43.209  -11.837 51.240  1.00 82.68  ?  171 TYR   A HD2  1 
ATOM   7567  H  HE1  . TYR   B 1 172 ? 43.230  -16.187 52.819  1.00 85.84  ?  171 TYR   A HE1  1 
ATOM   7568  H  HE2  . TYR   B 1 172 ? 45.226  -12.963 51.478  1.00 75.80  ?  171 TYR   A HE2  1 
ATOM   7569  H  HH   . TYR   B 1 172 ? 46.266  -14.799 52.234  1.00 93.25  ?  171 TYR   A HH   1 
ATOM   7570  N  N    . LEU   B 1 173 ? 37.756  -11.654 51.555  1.00 28.94  ?  172 LEU   A N    1 
ATOM   7571  C  CA   . LEU   B 1 173 ? 36.517  -11.190 52.152  1.00 33.83  ?  172 LEU   A CA   1 
ATOM   7572  C  C    . LEU   B 1 173 ? 35.318  -12.030 51.738  1.00 34.78  ?  172 LEU   A C    1 
ATOM   7573  O  O    . LEU   B 1 173 ? 34.464  -12.346 52.576  1.00 41.02  ?  172 LEU   A O    1 
ATOM   7574  C  CB   . LEU   B 1 173 ? 36.274  -9.747  51.770  1.00 36.70  ?  172 LEU   A CB   1 
ATOM   7575  C  CG   . LEU   B 1 173 ? 37.404  -8.823  52.218  1.00 37.54  ?  172 LEU   A CG   1 
ATOM   7576  C  CD1  . LEU   B 1 173 ? 37.042  -7.387  51.781  1.00 38.44  ?  172 LEU   A CD1  1 
ATOM   7577  C  CD2  . LEU   B 1 173 ? 37.615  -8.884  53.703  1.00 45.44  ?  172 LEU   A CD2  1 
ATOM   7578  H  H    . LEU   B 1 173 ? 38.161  -11.073 51.068  1.00 34.73  ?  172 LEU   A H    1 
ATOM   7579  H  HA   . LEU   B 1 173 ? 36.611  -11.260 53.115  1.00 40.60  ?  172 LEU   A HA   1 
ATOM   7580  H  HB2  . LEU   B 1 173 ? 36.198  -9.684  50.805  1.00 44.04  ?  172 LEU   A HB2  1 
ATOM   7581  H  HB3  . LEU   B 1 173 ? 35.453  -9.444  52.189  1.00 44.04  ?  172 LEU   A HB3  1 
ATOM   7582  H  HG   . LEU   B 1 173 ? 38.241  -9.098  51.810  1.00 45.05  ?  172 LEU   A HG   1 
ATOM   7583  H  HD11 . LEU   B 1 173 ? 37.727  -6.778  52.097  1.00 46.13  ?  172 LEU   A HD11 1 
ATOM   7584  H  HD12 . LEU   B 1 173 ? 36.992  -7.355  50.812  1.00 46.13  ?  172 LEU   A HD12 1 
ATOM   7585  H  HD13 . LEU   B 1 173 ? 36.184  -7.147  52.164  1.00 46.13  ?  172 LEU   A HD13 1 
ATOM   7586  H  HD21 . LEU   B 1 173 ? 38.308  -8.253  53.950  1.00 54.53  ?  172 LEU   A HD21 1 
ATOM   7587  H  HD22 . LEU   B 1 173 ? 36.785  -8.656  54.149  1.00 54.53  ?  172 LEU   A HD22 1 
ATOM   7588  H  HD23 . LEU   B 1 173 ? 37.885  -9.784  53.946  1.00 54.53  ?  172 LEU   A HD23 1 
ATOM   7589  N  N    . PHE   B 1 174 ? 35.188  -12.346 50.451  1.00 36.70  ?  173 PHE   A N    1 
ATOM   7590  C  CA   . PHE   B 1 174 ? 34.055  -13.162 50.030  1.00 36.72  ?  173 PHE   A CA   1 
ATOM   7591  C  C    . PHE   B 1 174 ? 33.968  -14.435 50.850  1.00 35.33  ?  173 PHE   A C    1 
ATOM   7592  O  O    . PHE   B 1 174 ? 32.872  -14.931 51.076  1.00 32.13  ?  173 PHE   A O    1 
ATOM   7593  C  CB   . PHE   B 1 174 ? 34.153  -13.494 48.547  1.00 36.79  ?  173 PHE   A CB   1 
ATOM   7594  C  CG   . PHE   B 1 174 ? 34.002  -12.286 47.647  1.00 34.51  ?  173 PHE   A CG   1 
ATOM   7595  C  CD1  . PHE   B 1 174 ? 33.404  -11.114 48.128  1.00 28.36  ?  173 PHE   A CD1  1 
ATOM   7596  C  CD2  . PHE   B 1 174 ? 34.482  -12.322 46.332  1.00 35.60  ?  173 PHE   A CD2  1 
ATOM   7597  C  CE1  . PHE   B 1 174 ? 33.252  -10.000 47.308  1.00 31.74  ?  173 PHE   A CE1  1 
ATOM   7598  C  CE2  . PHE   B 1 174 ? 34.363  -11.210 45.487  1.00 36.27  ?  173 PHE   A CE2  1 
ATOM   7599  C  CZ   . PHE   B 1 174 ? 33.750  -10.036 45.969  1.00 36.15  ?  173 PHE   A CZ   1 
ATOM   7600  H  H    . PHE   B 1 174 ? 35.724  -12.107 49.822  1.00 44.04  ?  173 PHE   A H    1 
ATOM   7601  H  HA   . PHE   B 1 174 ? 33.239  -12.654 50.159  1.00 44.06  ?  173 PHE   A HA   1 
ATOM   7602  H  HB2  . PHE   B 1 174 ? 35.022  -13.889 48.371  1.00 44.14  ?  173 PHE   A HB2  1 
ATOM   7603  H  HB3  . PHE   B 1 174 ? 33.451  -14.124 48.320  1.00 44.14  ?  173 PHE   A HB3  1 
ATOM   7604  H  HD1  . PHE   B 1 174 ? 33.104  -11.079 49.007  1.00 34.04  ?  173 PHE   A HD1  1 
ATOM   7605  H  HD2  . PHE   B 1 174 ? 34.887  -13.097 46.015  1.00 42.73  ?  173 PHE   A HD2  1 
ATOM   7606  H  HE1  . PHE   B 1 174 ? 32.829  -9.236  47.629  1.00 38.08  ?  173 PHE   A HE1  1 
ATOM   7607  H  HE2  . PHE   B 1 174 ? 34.686  -11.247 44.615  1.00 43.53  ?  173 PHE   A HE2  1 
ATOM   7608  H  HZ   . PHE   B 1 174 ? 33.670  -9.290  45.420  1.00 43.38  ?  173 PHE   A HZ   1 
ATOM   7609  N  N    . GLN   B 1 175 ? 35.093  -14.963 51.336  1.00 34.31  ?  174 GLN   A N    1 
ATOM   7610  C  CA   . GLN   B 1 175 ? 35.030  -16.161 52.168  1.00 38.55  ?  174 GLN   A CA   1 
ATOM   7611  C  C    . GLN   B 1 175 ? 34.341  -15.900 53.506  1.00 37.78  ?  174 GLN   A C    1 
ATOM   7612  O  O    . GLN   B 1 175 ? 33.970  -16.857 54.200  1.00 43.35  ?  174 GLN   A O    1 
ATOM   7613  C  CB   . GLN   B 1 175 ? 36.441  -16.711 52.422  1.00 41.53  ?  174 GLN   A CB   1 
ATOM   7614  C  CG   . GLN   B 1 175 ? 37.350  -16.636 51.186  1.00 55.02  ?  174 GLN   A CG   1 
ATOM   7615  C  CD   . GLN   B 1 175 ? 37.738  -18.007 50.620  1.00 66.30  ?  174 GLN   A CD   1 
ATOM   7616  O  OE1  . GLN   B 1 175 ? 36.885  -18.752 50.107  1.00 64.51  ?  174 GLN   A OE1  1 
ATOM   7617  N  NE2  . GLN   B 1 175 ? 39.048  -18.332 50.688  1.00 68.24  ?  174 GLN   A NE2  1 
ATOM   7618  H  H    . GLN   B 1 175 ? 35.884  -14.653 51.201  1.00 41.17  ?  174 GLN   A H    1 
ATOM   7619  H  HA   . GLN   B 1 175 ? 34.525  -16.837 51.690  1.00 46.26  ?  174 GLN   A HA   1 
ATOM   7620  H  HB2  . GLN   B 1 175 ? 36.857  -16.195 53.131  1.00 49.83  ?  174 GLN   A HB2  1 
ATOM   7621  H  HB3  . GLN   B 1 175 ? 36.373  -17.642 52.687  1.00 49.83  ?  174 GLN   A HB3  1 
ATOM   7622  H  HG2  . GLN   B 1 175 ? 36.886  -16.148 50.488  1.00 66.03  ?  174 GLN   A HG2  1 
ATOM   7623  H  HG3  . GLN   B 1 175 ? 38.167  -16.173 51.428  1.00 66.03  ?  174 GLN   A HG3  1 
ATOM   7624  H  HE21 . GLN   B 1 175 ? 39.611  -17.781 51.035  1.00 81.89  ?  174 GLN   A HE21 1 
ATOM   7625  H  HE22 . GLN   B 1 175 ? 39.320  -19.089 50.384  1.00 81.89  ?  174 GLN   A HE22 1 
ATOM   7626  N  N    . HIS   B 1 176 ? 34.177  -14.631 53.893  1.00 35.84  ?  175 HIS   A N    1 
ATOM   7627  C  CA   . HIS   B 1 176 ? 33.456  -14.270 55.111  1.00 36.27  ?  175 HIS   A CA   1 
ATOM   7628  C  C    . HIS   B 1 176 ? 32.110  -13.628 54.795  1.00 36.09  ?  175 HIS   A C    1 
ATOM   7629  O  O    . HIS   B 1 176 ? 31.516  -12.947 55.641  1.00 38.79  ?  175 HIS   A O    1 
ATOM   7630  C  CB   . HIS   B 1 176 ? 34.298  -13.332 55.979  1.00 33.23  ?  175 HIS   A CB   1 
ATOM   7631  C  CG   . HIS   B 1 176 ? 35.399  -14.042 56.717  1.00 44.75  ?  175 HIS   A CG   1 
ATOM   7632  N  ND1  . HIS   B 1 176 ? 36.712  -14.078 56.271  1.00 43.20  ?  175 HIS   A ND1  1 
ATOM   7633  C  CD2  . HIS   B 1 176 ? 35.365  -14.802 57.840  1.00 44.77  ?  175 HIS   A CD2  1 
ATOM   7634  C  CE1  . HIS   B 1 176 ? 37.432  -14.809 57.106  1.00 47.40  ?  175 HIS   A CE1  1 
ATOM   7635  N  NE2  . HIS   B 1 176 ? 36.636  -15.274 58.055  1.00 49.03  ?  175 HIS   A NE2  1 
ATOM   7636  H  H    . HIS   B 1 176 ? 34.479  -13.954 53.458  1.00 43.00  ?  175 HIS   A H    1 
ATOM   7637  H  HA   . HIS   B 1 176 ? 33.295  -15.077 55.625  1.00 43.52  ?  175 HIS   A HA   1 
ATOM   7638  H  HB2  . HIS   B 1 176 ? 34.704  -12.658 55.411  1.00 39.88  ?  175 HIS   A HB2  1 
ATOM   7639  H  HB3  . HIS   B 1 176 ? 33.722  -12.909 56.635  1.00 39.88  ?  175 HIS   A HB3  1 
ATOM   7640  H  HD2  . HIS   B 1 176 ? 34.618  -14.972 58.368  1.00 53.72  ?  175 HIS   A HD2  1 
ATOM   7641  H  HE1  . HIS   B 1 176 ? 38.346  -14.970 57.037  1.00 56.89  ?  175 HIS   A HE1  1 
ATOM   7642  H  HE2  . HIS   B 1 176 ? 36.875  -15.788 58.701  1.00 58.84  ?  175 HIS   A HE2  1 
ATOM   7643  N  N    . ALA   B 1 177 ? 31.622  -13.809 53.587  1.00 31.19  ?  176 ALA   A N    1 
ATOM   7644  C  CA   . ALA   B 1 177 ? 30.343  -13.269 53.177  1.00 35.06  ?  176 ALA   A CA   1 
ATOM   7645  C  C    . ALA   B 1 177 ? 29.419  -14.444 52.941  1.00 36.85  ?  176 ALA   A C    1 
ATOM   7646  O  O    . ALA   B 1 177 ? 29.877  -15.550 52.652  1.00 37.20  ?  176 ALA   A O    1 
ATOM   7647  C  CB   . ALA   B 1 177 ? 30.491  -12.405 51.943  1.00 35.68  ?  176 ALA   A CB   1 
ATOM   7648  H  H    . ALA   B 1 177 ? 32.023  -14.253 52.970  1.00 37.42  ?  176 ALA   A H    1 
ATOM   7649  H  HA   . ALA   B 1 177 ? 29.948  -12.699 53.856  1.00 42.07  ?  176 ALA   A HA   1 
ATOM   7650  H  HB1  . ALA   B 1 177 ? 29.611  -12.127 51.644  1.00 42.82  ?  176 ALA   A HB1  1 
ATOM   7651  H  HB2  . ALA   B 1 177 ? 31.026  -11.627 52.164  1.00 42.82  ?  176 ALA   A HB2  1 
ATOM   7652  H  HB3  . ALA   B 1 177 ? 30.929  -12.920 51.247  1.00 42.82  ?  176 ALA   A HB3  1 
ATOM   7653  N  N    . ASN   B 1 178 ? 28.124  -14.218 53.118  1.00 42.09  ?  177 ASN   A N    1 
ATOM   7654  C  CA   . ASN   B 1 178 ? 27.151  -15.265 52.826  1.00 48.25  ?  177 ASN   A CA   1 
ATOM   7655  C  C    . ASN   B 1 178 ? 26.923  -15.220 51.321  1.00 47.81  ?  177 ASN   A C    1 
ATOM   7656  O  O    . ASN   B 1 178 ? 26.232  -14.322 50.814  1.00 40.45  ?  177 ASN   A O    1 
ATOM   7657  C  CB   . ASN   B 1 178 ? 25.854  -15.077 53.594  1.00 49.93  ?  177 ASN   A CB   1 
ATOM   7658  C  CG   . ASN   B 1 178 ? 24.857  -16.196 53.303  1.00 54.37  ?  177 ASN   A CG   1 
ATOM   7659  O  OD1  . ASN   B 1 178 ? 24.573  -16.497 52.141  1.00 53.00  ?  177 ASN   A OD1  1 
ATOM   7660  N  ND2  . ASN   B 1 178 ? 24.343  -16.835 54.364  1.00 58.35  ?  177 ASN   A ND2  1 
ATOM   7661  H  H    . ASN   B 1 178 ? 27.788  -13.478 53.401  1.00 50.51  ?  177 ASN   A H    1 
ATOM   7662  H  HA   . ASN   B 1 178 ? 27.503  -16.128 53.092  1.00 57.90  ?  177 ASN   A HA   1 
ATOM   7663  H  HB2  . ASN   B 1 178 ? 26.043  -15.077 54.545  1.00 59.92  ?  177 ASN   A HB2  1 
ATOM   7664  H  HB3  . ASN   B 1 178 ? 25.449  -14.234 53.336  1.00 59.92  ?  177 ASN   A HB3  1 
ATOM   7665  H  HD21 . ASN   B 1 178 ? 24.578  -16.607 55.160  1.00 70.02  ?  177 ASN   A HD21 1 
ATOM   7666  H  HD22 . ASN   B 1 178 ? 23.777  -17.473 54.250  1.00 70.02  ?  177 ASN   A HD22 1 
ATOM   7667  N  N    . LEU   B 1 179 ? 27.544  -16.180 50.607  1.00 40.97  ?  178 LEU   A N    1 
ATOM   7668  C  CA   . LEU   B 1 179 ? 27.305  -16.432 49.189  1.00 40.36  ?  178 LEU   A CA   1 
ATOM   7669  C  C    . LEU   B 1 179 ? 26.860  -17.871 48.931  1.00 40.28  ?  178 LEU   A C    1 
ATOM   7670  O  O    . LEU   B 1 179 ? 27.053  -18.413 47.828  1.00 35.97  ?  178 LEU   A O    1 
ATOM   7671  C  CB   . LEU   B 1 179 ? 28.554  -16.111 48.385  1.00 44.87  ?  178 LEU   A CB   1 
ATOM   7672  C  CG   . LEU   B 1 179 ? 28.983  -14.655 48.482  1.00 45.55  ?  178 LEU   A CG   1 
ATOM   7673  C  CD1  . LEU   B 1 179 ? 30.363  -14.576 47.916  1.00 46.50  ?  178 LEU   A CD1  1 
ATOM   7674  C  CD2  . LEU   B 1 179 ? 28.016  -13.756 47.751  1.00 41.59  ?  178 LEU   A CD2  1 
ATOM   7675  H  H    . LEU   B 1 179 ? 28.128  -16.714 50.943  1.00 49.16  ?  178 LEU   A H    1 
ATOM   7676  H  HA   . LEU   B 1 179 ? 26.587  -15.852 48.891  1.00 48.43  ?  178 LEU   A HA   1 
ATOM   7677  H  HB2  . LEU   B 1 179 ? 29.284  -16.659 48.712  1.00 53.84  ?  178 LEU   A HB2  1 
ATOM   7678  H  HB3  . LEU   B 1 179 ? 28.383  -16.309 47.451  1.00 53.84  ?  178 LEU   A HB3  1 
ATOM   7679  H  HG   . LEU   B 1 179 ? 28.985  -14.340 49.399  1.00 54.66  ?  178 LEU   A HG   1 
ATOM   7680  H  HD11 . LEU   B 1 179 ? 30.634  -13.646 47.870  1.00 55.80  ?  178 LEU   A HD11 1 
ATOM   7681  H  HD12 . LEU   B 1 179 ? 30.969  -15.069 48.492  1.00 55.80  ?  178 LEU   A HD12 1 
ATOM   7682  H  HD13 . LEU   B 1 179 ? 30.363  -14.965 47.028  1.00 55.80  ?  178 LEU   A HD13 1 
ATOM   7683  H  HD21 . LEU   B 1 179 ? 28.476  -13.335 47.007  1.00 49.91  ?  178 LEU   A HD21 1 
ATOM   7684  H  HD22 . LEU   B 1 179 ? 27.275  -14.289 47.423  1.00 49.91  ?  178 LEU   A HD22 1 
ATOM   7685  H  HD23 . LEU   B 1 179 ? 27.689  -13.078 48.364  1.00 49.91  ?  178 LEU   A HD23 1 
ATOM   7686  N  N    . ASP   B 1 180 ? 26.215  -18.470 49.937  1.00 48.99  ?  179 ASP   A N    1 
ATOM   7687  C  CA   . ASP   B 1 180 ? 25.800  -19.871 49.874  1.00 55.76  ?  179 ASP   A CA   1 
ATOM   7688  C  C    . ASP   B 1 180 ? 24.958  -20.147 48.642  1.00 49.54  ?  179 ASP   A C    1 
ATOM   7689  O  O    . ASP   B 1 180 ? 25.218  -21.098 47.889  1.00 48.66  ?  179 ASP   A O    1 
ATOM   7690  C  CB   . ASP   B 1 180 ? 24.982  -20.249 51.117  1.00 60.20  ?  179 ASP   A CB   1 
ATOM   7691  C  CG   . ASP   B 1 180 ? 25.766  -20.136 52.402  1.00 63.26  ?  179 ASP   A CG   1 
ATOM   7692  O  OD1  . ASP   B 1 180 ? 25.132  -20.188 53.481  1.00 66.83  ?  179 ASP   A OD1  1 
ATOM   7693  O  OD2  . ASP   B 1 180 ? 27.005  -20.025 52.343  1.00 59.32  ?  179 ASP   A OD2  1 
ATOM   7694  H  H    . ASP   B 1 180 ? 26.004  -18.082 50.675  1.00 58.79  ?  179 ASP   A H    1 
ATOM   7695  H  HA   . ASP   B 1 180 ? 26.605  -20.411 49.843  1.00 66.92  ?  179 ASP   A HA   1 
ATOM   7696  H  HB2  . ASP   B 1 180 ? 24.217  -19.656 51.182  1.00 72.24  ?  179 ASP   A HB2  1 
ATOM   7697  H  HB3  . ASP   B 1 180 ? 24.683  -21.167 51.030  1.00 72.24  ?  179 ASP   A HB3  1 
ATOM   7698  N  N    . SER   B 1 181 ? 23.920  -19.338 48.449  1.00 38.11  ?  180 SER   A N    1 
ATOM   7699  C  CA   . SER   B 1 181 ? 23.020  -19.506 47.322  1.00 39.06  ?  180 SER   A CA   1 
ATOM   7700  C  C    . SER   B 1 181 ? 23.637  -19.163 45.962  1.00 46.61  ?  180 SER   A C    1 
ATOM   7701  O  O    . SER   B 1 181 ? 23.006  -19.418 44.932  1.00 46.51  ?  180 SER   A O    1 
ATOM   7702  C  CB   . SER   B 1 181 ? 21.813  -18.649 47.572  1.00 36.42  ?  180 SER   A CB   1 
ATOM   7703  O  OG   . SER   B 1 181 ? 22.146  -17.292 47.442  1.00 42.72  ?  180 SER   A OG   1 
ATOM   7704  H  H    . SER   B 1 181 ? 23.716  -18.679 48.962  1.00 45.73  ?  180 SER   A H    1 
ATOM   7705  H  HA   . SER   B 1 181 ? 22.758  -20.438 47.260  1.00 46.88  ?  180 SER   A HA   1 
ATOM   7706  H  HB2  . SER   B 1 181 ? 21.125  -18.871 46.925  1.00 43.70  ?  180 SER   A HB2  1 
ATOM   7707  H  HB3  . SER   B 1 181 ? 21.487  -18.811 48.471  1.00 43.70  ?  180 SER   A HB3  1 
ATOM   7708  H  HG   . SER   B 1 181 ? 21.451  -16.822 47.462  1.00 51.26  ?  180 SER   A HG   1 
ATOM   7709  N  N    . CYS   B 1 182 ? 24.836  -18.608 45.900  1.00 39.09  ?  181 CYS   A N    1 
ATOM   7710  C  CA   . CYS   B 1 182 ? 25.364  -18.258 44.585  1.00 33.19  ?  181 CYS   A CA   1 
ATOM   7711  C  C    . CYS   B 1 182 ? 25.718  -19.502 43.799  1.00 30.22  ?  181 CYS   A C    1 
ATOM   7712  O  O    . CYS   B 1 182 ? 26.270  -20.466 44.343  1.00 35.26  ?  181 CYS   A O    1 
ATOM   7713  C  CB   . CYS   B 1 182 ? 26.577  -17.382 44.699  1.00 28.09  ?  181 CYS   A CB   1 
ATOM   7714  S  SG   . CYS   B 1 182 ? 26.135  -15.755 45.215  1.00 41.36  ?  181 CYS   A SG   1 
ATOM   7715  H  H    . CYS   B 1 182 ? 25.343  -18.430 46.571  1.00 46.90  ?  181 CYS   A H    1 
ATOM   7716  H  HA   . CYS   B 1 182 ? 24.680  -17.765 44.106  1.00 39.83  ?  181 CYS   A HA   1 
ATOM   7717  H  HB2  . CYS   B 1 182 ? 27.186  -17.757 45.354  1.00 33.71  ?  181 CYS   A HB2  1 
ATOM   7718  H  HB3  . CYS   B 1 182 ? 27.015  -17.323 43.835  1.00 33.71  ?  181 CYS   A HB3  1 
ATOM   7719  H  HG   . CYS   B 1 182 ? 27.135  -15.119 45.402  1.00 49.64  ?  181 CYS   A HG   1 
ATOM   7720  N  N    . LYS   B 1 183 ? 25.415  -19.460 42.501  1.00 26.57  ?  182 LYS   A N    1 
ATOM   7721  C  CA   . LYS   B 1 183 ? 25.494  -20.622 41.635  1.00 30.36  ?  182 LYS   A CA   1 
ATOM   7722  C  C    . LYS   B 1 183 ? 25.922  -20.196 40.238  1.00 30.21  ?  182 LYS   A C    1 
ATOM   7723  O  O    . LYS   B 1 183 ? 25.431  -19.193 39.708  1.00 37.46  ?  182 LYS   A O    1 
ATOM   7724  C  CB   . LYS   B 1 183 ? 24.127  -21.325 41.565  1.00 34.32  ?  182 LYS   A CB   1 
ATOM   7725  C  CG   . LYS   B 1 183 ? 24.139  -22.764 41.140  1.00 37.98  ?  182 LYS   A CG   1 
ATOM   7726  C  CD   . LYS   B 1 183 ? 22.782  -23.107 40.455  1.00 39.81  ?  182 LYS   A CD   1 
ATOM   7727  C  CE   . LYS   B 1 183 ? 22.568  -24.631 40.414  1.00 51.24  ?  182 LYS   A CE   1 
ATOM   7728  N  NZ   . LYS   B 1 183 ? 21.365  -25.007 39.601  1.00 65.76  ?  182 LYS   A NZ   1 
ATOM   7729  H  H    . LYS   B 1 183 ? 25.154  -18.749 42.094  1.00 31.88  ?  182 LYS   A H    1 
ATOM   7730  H  HA   . LYS   B 1 183 ? 26.163  -21.238 41.973  1.00 36.43  ?  182 LYS   A HA   1 
ATOM   7731  H  HB2  . LYS   B 1 183 ? 23.726  -21.292 42.448  1.00 41.18  ?  182 LYS   A HB2  1 
ATOM   7732  H  HB3  . LYS   B 1 183 ? 23.573  -20.845 40.930  1.00 41.18  ?  182 LYS   A HB3  1 
ATOM   7733  H  HG2  . LYS   B 1 183 ? 24.858  -22.915 40.507  1.00 45.58  ?  182 LYS   A HG2  1 
ATOM   7734  H  HG3  . LYS   B 1 183 ? 24.253  -23.336 41.915  1.00 45.58  ?  182 LYS   A HG3  1 
ATOM   7735  H  HD2  . LYS   B 1 183 ? 22.054  -22.706 40.955  1.00 47.77  ?  182 LYS   A HD2  1 
ATOM   7736  H  HD3  . LYS   B 1 183 ? 22.783  -22.771 39.545  1.00 47.77  ?  182 LYS   A HD3  1 
ATOM   7737  H  HE2  . LYS   B 1 183 ? 23.346  -25.052 40.016  1.00 61.49  ?  182 LYS   A HE2  1 
ATOM   7738  H  HE3  . LYS   B 1 183 ? 22.438  -24.959 41.317  1.00 61.49  ?  182 LYS   A HE3  1 
ATOM   7739  H  HZ1  . LYS   B 1 183 ? 21.285  -25.892 39.567  1.00 78.91  ?  182 LYS   A HZ1  1 
ATOM   7740  H  HZ2  . LYS   B 1 183 ? 20.630  -24.664 39.968  1.00 78.91  ?  182 LYS   A HZ2  1 
ATOM   7741  H  HZ3  . LYS   B 1 183 ? 21.447  -24.692 38.772  1.00 78.91  ?  182 LYS   A HZ3  1 
ATOM   7742  N  N    . ARG   B 1 184 ? 26.812  -20.984 39.628  1.00 30.16  ?  183 ARG   A N    1 
ATOM   7743  C  CA   . ARG   B 1 184 ? 27.216  -20.754 38.246  1.00 32.42  ?  183 ARG   A CA   1 
ATOM   7744  C  C    . ARG   B 1 184 ? 27.269  -22.085 37.534  1.00 29.56  ?  183 ARG   A C    1 
ATOM   7745  O  O    . ARG   B 1 184 ? 27.733  -23.068 38.098  1.00 29.66  ?  183 ARG   A O    1 
ATOM   7746  C  CB   . ARG   B 1 184 ? 28.558  -20.057 38.156  1.00 32.15  ?  183 ARG   A CB   1 
ATOM   7747  C  CG   . ARG   B 1 184 ? 29.302  -20.230 36.851  1.00 34.35  ?  183 ARG   A CG   1 
ATOM   7748  C  CD   . ARG   B 1 184 ? 30.639  -19.434 36.926  1.00 34.37  ?  183 ARG   A CD   1 
ATOM   7749  N  NE   . ARG   B 1 184 ? 30.349  -18.010 36.903  1.00 32.56  ?  183 ARG   A NE   1 
ATOM   7750  C  CZ   . ARG   B 1 184 ? 31.213  -17.046 37.192  1.00 36.97  ?  183 ARG   A CZ   1 
ATOM   7751  N  NH1  . ARG   B 1 184 ? 32.489  -17.309 37.494  1.00 39.77  ?  183 ARG   A NH1  1 
ATOM   7752  N  NH2  . ARG   B 1 184 ? 30.783  -15.786 37.182  1.00 32.98  ?  183 ARG   A NH2  1 
ATOM   7753  H  H    . ARG   B 1 184 ? 27.196  -21.659 39.998  1.00 36.20  ?  183 ARG   A H    1 
ATOM   7754  H  HA   . ARG   B 1 184 ? 26.565  -20.188 37.803  1.00 38.90  ?  183 ARG   A HA   1 
ATOM   7755  H  HB2  . ARG   B 1 184 ? 28.415  -19.106 38.282  1.00 38.59  ?  183 ARG   A HB2  1 
ATOM   7756  H  HB3  . ARG   B 1 184 ? 29.128  -20.403 38.860  1.00 38.59  ?  183 ARG   A HB3  1 
ATOM   7757  H  HG2  . ARG   B 1 184 ? 29.500  -21.168 36.704  1.00 41.21  ?  183 ARG   A HG2  1 
ATOM   7758  H  HG3  . ARG   B 1 184 ? 28.769  -19.884 36.117  1.00 41.21  ?  183 ARG   A HG3  1 
ATOM   7759  H  HD2  . ARG   B 1 184 ? 31.104  -19.648 37.750  1.00 41.25  ?  183 ARG   A HD2  1 
ATOM   7760  H  HD3  . ARG   B 1 184 ? 31.197  -19.654 36.163  1.00 41.25  ?  183 ARG   A HD3  1 
ATOM   7761  H  HE   . ARG   B 1 184 ? 29.552  -17.773 36.684  1.00 39.07  ?  183 ARG   A HE   1 
ATOM   7762  H  HH11 . ARG   B 1 184 ? 32.770  -18.122 37.504  1.00 47.72  ?  183 ARG   A HH11 1 
ATOM   7763  H  HH12 . ARG   B 1 184 ? 33.029  -16.665 37.677  1.00 47.72  ?  183 ARG   A HH12 1 
ATOM   7764  H  HH21 . ARG   B 1 184 ? 29.962  -15.613 36.992  1.00 39.58  ?  183 ARG   A HH21 1 
ATOM   7765  H  HH22 . ARG   B 1 184 ? 31.325  -15.144 37.366  1.00 39.58  ?  183 ARG   A HH22 1 
ATOM   7766  N  N    . VAL   B 1 185 ? 26.737  -22.126 36.321  1.00 30.56  ?  184 VAL   A N    1 
ATOM   7767  C  CA   . VAL   B 1 185 ? 26.782  -23.316 35.481  1.00 33.75  ?  184 VAL   A CA   1 
ATOM   7768  C  C    . VAL   B 1 185 ? 27.568  -22.972 34.214  1.00 35.05  ?  184 VAL   A C    1 
ATOM   7769  O  O    . VAL   B 1 185 ? 27.280  -21.966 33.549  1.00 32.57  ?  184 VAL   A O    1 
ATOM   7770  C  CB   . VAL   B 1 185 ? 25.366  -23.825 35.146  1.00 32.43  ?  184 VAL   A CB   1 
ATOM   7771  C  CG1  . VAL   B 1 185 ? 25.450  -25.073 34.266  1.00 31.65  ?  184 VAL   A CG1  1 
ATOM   7772  C  CG2  . VAL   B 1 185 ? 24.577  -24.097 36.415  1.00 35.25  ?  184 VAL   A CG2  1 
ATOM   7773  H  H    . VAL   B 1 185 ? 26.335  -21.460 35.953  1.00 36.67  ?  184 VAL   A H    1 
ATOM   7774  H  HA   . VAL   B 1 185 ? 27.253  -24.027 35.943  1.00 40.50  ?  184 VAL   A HA   1 
ATOM   7775  H  HB   . VAL   B 1 185 ? 24.891  -23.140 34.651  1.00 38.91  ?  184 VAL   A HB   1 
ATOM   7776  H  HG11 . VAL   B 1 185 ? 24.559  -25.441 34.155  1.00 37.97  ?  184 VAL   A HG11 1 
ATOM   7777  H  HG12 . VAL   B 1 185 ? 25.816  -24.827 33.403  1.00 37.97  ?  184 VAL   A HG12 1 
ATOM   7778  H  HG13 . VAL   B 1 185 ? 26.026  -25.725 34.696  1.00 37.97  ?  184 VAL   A HG13 1 
ATOM   7779  H  HG21 . VAL   B 1 185 ? 23.700  -24.434 36.176  1.00 42.30  ?  184 VAL   A HG21 1 
ATOM   7780  H  HG22 . VAL   B 1 185 ? 25.051  -24.756 36.947  1.00 42.30  ?  184 VAL   A HG22 1 
ATOM   7781  H  HG23 . VAL   B 1 185 ? 24.489  -23.270 36.915  1.00 42.30  ?  184 VAL   A HG23 1 
ATOM   7782  N  N    . LEU   B 1 186 ? 28.566  -23.801 33.901  1.00 33.91  ?  185 LEU   A N    1 
ATOM   7783  C  CA   . LEU   B 1 186 ? 29.487  -23.618 32.799  1.00 32.31  ?  185 LEU   A CA   1 
ATOM   7784  C  C    . LEU   B 1 186 ? 29.474  -24.866 31.938  1.00 36.25  ?  185 LEU   A C    1 
ATOM   7785  O  O    . LEU   B 1 186 ? 29.389  -25.989 32.451  1.00 30.71  ?  185 LEU   A O    1 
ATOM   7786  C  CB   . LEU   B 1 186 ? 30.915  -23.412 33.278  1.00 39.10  ?  185 LEU   A CB   1 
ATOM   7787  C  CG   . LEU   B 1 186 ? 31.131  -22.158 34.115  1.00 44.18  ?  185 LEU   A CG   1 
ATOM   7788  C  CD1  . LEU   B 1 186 ? 32.546  -22.200 34.745  1.00 43.77  ?  185 LEU   A CD1  1 
ATOM   7789  C  CD2  . LEU   B 1 186 ? 30.943  -20.894 33.326  1.00 45.58  ?  185 LEU   A CD2  1 
ATOM   7790  H  H    . LEU   B 1 186 ? 28.732  -24.519 34.346  1.00 40.70  ?  185 LEU   A H    1 
ATOM   7791  H  HA   . LEU   B 1 186 ? 29.212  -22.842 32.286  1.00 38.77  ?  185 LEU   A HA   1 
ATOM   7792  H  HB2  . LEU   B 1 186 ? 31.171  -24.174 33.821  1.00 46.92  ?  185 LEU   A HB2  1 
ATOM   7793  H  HB3  . LEU   B 1 186 ? 31.493  -23.349 32.502  1.00 46.92  ?  185 LEU   A HB3  1 
ATOM   7794  H  HG   . LEU   B 1 186 ? 30.461  -22.140 34.816  1.00 53.01  ?  185 LEU   A HG   1 
ATOM   7795  H  HD11 . LEU   B 1 186 ? 32.680  -21.398 35.273  1.00 52.52  ?  185 LEU   A HD11 1 
ATOM   7796  H  HD12 . LEU   B 1 186 ? 32.616  -22.985 35.311  1.00 52.52  ?  185 LEU   A HD12 1 
ATOM   7797  H  HD13 . LEU   B 1 186 ? 33.206  -22.244 34.036  1.00 52.52  ?  185 LEU   A HD13 1 
ATOM   7798  H  HD21 . LEU   B 1 186 ? 31.056  -20.133 33.916  1.00 54.70  ?  185 LEU   A HD21 1 
ATOM   7799  H  HD22 . LEU   B 1 186 ? 31.604  -20.863 32.616  1.00 54.70  ?  185 LEU   A HD22 1 
ATOM   7800  H  HD23 . LEU   B 1 186 ? 30.050  -20.888 32.947  1.00 54.70  ?  185 LEU   A HD23 1 
ATOM   7801  N  N    . ASN   B 1 187 ? 29.593  -24.644 30.629  1.00 35.48  ?  186 ASN   A N    1 
ATOM   7802  C  CA   . ASN   B 1 187 ? 29.708  -25.673 29.601  1.00 36.97  ?  186 ASN   A CA   1 
ATOM   7803  C  C    . ASN   B 1 187 ? 31.023  -25.508 28.846  1.00 35.99  ?  186 ASN   A C    1 
ATOM   7804  O  O    . ASN   B 1 187 ? 31.420  -24.387 28.522  1.00 33.57  ?  186 ASN   A O    1 
ATOM   7805  C  CB   . ASN   B 1 187 ? 28.522  -25.575 28.629  1.00 36.90  ?  186 ASN   A CB   1 
ATOM   7806  C  CG   . ASN   B 1 187 ? 28.283  -26.856 27.874  1.00 44.70  ?  186 ASN   A CG   1 
ATOM   7807  O  OD1  . ASN   B 1 187 ? 28.608  -27.945 28.352  1.00 52.37  ?  186 ASN   A OD1  1 
ATOM   7808  N  ND2  . ASN   B 1 187 ? 27.692  -26.739 26.684  1.00 51.76  ?  186 ASN   A ND2  1 
ATOM   7809  H  H    . ASN   B 1 187 ? 29.612  -23.853 30.292  1.00 42.58  ?  186 ASN   A H    1 
ATOM   7810  H  HA   . ASN   B 1 187 ? 29.713  -26.555 30.005  1.00 44.37  ?  186 ASN   A HA   1 
ATOM   7811  H  HB2  . ASN   B 1 187 ? 27.718  -25.367 29.131  1.00 44.28  ?  186 ASN   A HB2  1 
ATOM   7812  H  HB3  . ASN   B 1 187 ? 28.700  -24.874 27.983  1.00 44.28  ?  186 ASN   A HB3  1 
ATOM   7813  H  HD21 . ASN   B 1 187 ? 27.471  -25.963 26.388  1.00 62.11  ?  186 ASN   A HD21 1 
ATOM   7814  H  HD22 . ASN   B 1 187 ? 27.533  -27.441 26.212  1.00 62.11  ?  186 ASN   A HD22 1 
ATOM   7815  N  N    . VAL   B 1 188 ? 31.700  -26.623 28.585  1.00 40.31  ?  187 VAL   A N    1 
ATOM   7816  C  CA   . VAL   B 1 188 ? 32.894  -26.676 27.723  1.00 42.52  ?  187 VAL   A CA   1 
ATOM   7817  C  C    . VAL   B 1 188 ? 32.603  -27.612 26.554  1.00 44.03  ?  187 VAL   A C    1 
ATOM   7818  O  O    . VAL   B 1 188 ? 32.402  -28.814 26.762  1.00 47.31  ?  187 VAL   A O    1 
ATOM   7819  C  CB   . VAL   B 1 188 ? 34.128  -27.158 28.505  1.00 41.07  ?  187 VAL   A CB   1 
ATOM   7820  C  CG1  . VAL   B 1 188 ? 35.355  -27.295 27.580  1.00 48.29  ?  187 VAL   A CG1  1 
ATOM   7821  C  CG2  . VAL   B 1 188 ? 34.431  -26.260 29.727  1.00 34.41  ?  187 VAL   A CG2  1 
ATOM   7822  H  H    . VAL   B 1 188 ? 31.484  -27.392 28.904  1.00 48.37  ?  187 VAL   A H    1 
ATOM   7823  H  HA   . VAL   B 1 188 ? 33.069  -25.791 27.367  1.00 51.02  ?  187 VAL   A HA   1 
ATOM   7824  H  HB   . VAL   B 1 188 ? 33.927  -28.040 28.856  1.00 49.29  ?  187 VAL   A HB   1 
ATOM   7825  H  HG11 . VAL   B 1 188 ? 36.120  -27.572 28.109  1.00 57.95  ?  187 VAL   A HG11 1 
ATOM   7826  H  HG12 . VAL   B 1 188 ? 35.165  -27.961 26.901  1.00 57.95  ?  187 VAL   A HG12 1 
ATOM   7827  H  HG13 . VAL   B 1 188 ? 35.533  -26.438 27.162  1.00 57.95  ?  187 VAL   A HG13 1 
ATOM   7828  H  HG21 . VAL   B 1 188 ? 35.163  -26.650 30.231  1.00 41.29  ?  187 VAL   A HG21 1 
ATOM   7829  H  HG22 . VAL   B 1 188 ? 34.678  -25.376 29.415  1.00 41.29  ?  187 VAL   A HG22 1 
ATOM   7830  H  HG23 . VAL   B 1 188 ? 33.638  -26.206 30.283  1.00 41.29  ?  187 VAL   A HG23 1 
ATOM   7831  N  N    . VAL   B 1 189 ? 32.584  -27.076 25.331  1.00 40.59  ?  188 VAL   A N    1 
ATOM   7832  C  CA   . VAL   B 1 189 ? 32.206  -27.858 24.153  1.00 47.31  ?  188 VAL   A CA   1 
ATOM   7833  C  C    . VAL   B 1 189 ? 33.391  -28.003 23.207  1.00 55.96  ?  188 VAL   A C    1 
ATOM   7834  O  O    . VAL   B 1 189 ? 34.032  -27.011 22.831  1.00 55.72  ?  188 VAL   A O    1 
ATOM   7835  C  CB   . VAL   B 1 189 ? 31.013  -27.257 23.389  1.00 44.13  ?  188 VAL   A CB   1 
ATOM   7836  C  CG1  . VAL   B 1 189 ? 29.858  -27.024 24.303  1.00 47.14  ?  188 VAL   A CG1  1 
ATOM   7837  C  CG2  . VAL   B 1 189 ? 31.413  -25.971 22.701  1.00 54.02  ?  188 VAL   A CG2  1 
ATOM   7838  H  H    . VAL   B 1 189 ? 32.787  -26.258 25.159  1.00 48.71  ?  188 VAL   A H    1 
ATOM   7839  H  HA   . VAL   B 1 189 ? 31.963  -28.738 24.480  1.00 56.77  ?  188 VAL   A HA   1 
ATOM   7840  H  HB   . VAL   B 1 189 ? 30.733  -27.890 22.709  1.00 52.96  ?  188 VAL   A HB   1 
ATOM   7841  H  HG11 . VAL   B 1 189 ? 29.049  -26.937 23.774  1.00 56.56  ?  188 VAL   A HG11 1 
ATOM   7842  H  HG12 . VAL   B 1 189 ? 29.778  -27.777 24.909  1.00 56.56  ?  188 VAL   A HG12 1 
ATOM   7843  H  HG13 . VAL   B 1 189 ? 30.013  -26.209 24.806  1.00 56.56  ?  188 VAL   A HG13 1 
ATOM   7844  H  HG21 . VAL   B 1 189 ? 30.621  -25.432 22.554  1.00 64.83  ?  188 VAL   A HG21 1 
ATOM   7845  H  HG22 . VAL   B 1 189 ? 32.039  -25.492 23.267  1.00 64.83  ?  188 VAL   A HG22 1 
ATOM   7846  H  HG23 . VAL   B 1 189 ? 31.831  -26.184 21.852  1.00 64.83  ?  188 VAL   A HG23 1 
ATOM   7847  N  N    . CYS   B 1 190 ? 33.672  -29.249 22.822  1.00 68.47  ?  189 CYS   A N    1 
ATOM   7848  C  CA   . CYS   B 1 190 ? 34.558  -29.563 21.715  1.00 74.16  ?  189 CYS   A CA   1 
ATOM   7849  C  C    . CYS   B 1 190 ? 33.802  -30.308 20.618  1.00 81.27  ?  189 CYS   A C    1 
ATOM   7850  O  O    . CYS   B 1 190 ? 32.822  -31.014 20.884  1.00 67.81  ?  189 CYS   A O    1 
ATOM   7851  C  CB   . CYS   B 1 190 ? 35.711  -30.420 22.151  1.00 69.03  ?  189 CYS   A CB   1 
ATOM   7852  S  SG   . CYS   B 1 190 ? 36.829  -30.656 20.787  1.00 105.84 ?  189 CYS   A SG   1 
ATOM   7853  H  H    . CYS   B 1 190 ? 33.347  -29.948 23.203  1.00 82.16  ?  189 CYS   A H    1 
ATOM   7854  H  HA   . CYS   B 1 190 ? 34.898  -28.729 21.356  1.00 88.99  ?  189 CYS   A HA   1 
ATOM   7855  N  N    . LYS   B 1 191 ? 34.285  -30.169 19.376  1.00 96.95  ?  190 LYS   A N    1 
ATOM   7856  C  CA   . LYS   B 1 191 ? 33.636  -30.820 18.242  1.00 98.18  ?  190 LYS   A CA   1 
ATOM   7857  C  C    . LYS   B 1 191 ? 33.917  -32.319 18.177  1.00 91.61  ?  190 LYS   A C    1 
ATOM   7858  O  O    . LYS   B 1 191 ? 33.190  -33.035 17.483  1.00 79.60  ?  190 LYS   A O    1 
ATOM   7859  C  CB   . LYS   B 1 191 ? 34.069  -30.142 16.938  1.00 103.64 ?  190 LYS   A CB   1 
ATOM   7860  C  CG   . LYS   B 1 191 ? 34.326  -28.633 17.059  1.00 118.25 ?  190 LYS   A CG   1 
ATOM   7861  C  CD   . LYS   B 1 191 ? 34.363  -27.931 15.693  1.00 107.22 ?  190 LYS   A CD   1 
ATOM   7862  C  CE   . LYS   B 1 191 ? 35.768  -27.943 15.075  1.00 97.32  ?  190 LYS   A CE   1 
ATOM   7863  N  NZ   . LYS   B 1 191 ? 36.787  -27.136 15.839  1.00 86.16  ?  190 LYS   A NZ   1 
ATOM   7864  H  H    . LYS   B 1 191 ? 34.981  -29.707 19.171  1.00 116.34 ?  190 LYS   A H    1 
ATOM   7865  H  HA   . LYS   B 1 191 ? 32.676  -30.714 18.325  1.00 117.81 ?  190 LYS   A HA   1 
ATOM   7866  H  HB2  . LYS   B 1 191 ? 34.892  -30.556 16.633  1.00 124.37 ?  190 LYS   A HB2  1 
ATOM   7867  H  HB3  . LYS   B 1 191 ? 33.370  -30.268 16.277  1.00 124.37 ?  190 LYS   A HB3  1 
ATOM   7868  H  HG2  . LYS   B 1 191 ? 33.616  -28.231 17.584  1.00 141.90 ?  190 LYS   A HG2  1 
ATOM   7869  H  HG3  . LYS   B 1 191 ? 35.182  -28.490 17.494  1.00 141.90 ?  190 LYS   A HG3  1 
ATOM   7870  H  HD2  . LYS   B 1 191 ? 33.761  -28.387 15.084  1.00 128.66 ?  190 LYS   A HD2  1 
ATOM   7871  H  HD3  . LYS   B 1 191 ? 34.089  -27.007 15.802  1.00 128.66 ?  190 LYS   A HD3  1 
ATOM   7872  H  HE2  . LYS   B 1 191 ? 36.085  -28.859 15.041  1.00 116.79 ?  190 LYS   A HE2  1 
ATOM   7873  H  HE3  . LYS   B 1 191 ? 35.716  -27.576 14.178  1.00 116.79 ?  190 LYS   A HE3  1 
ATOM   7874  H  HZ1  . LYS   B 1 191 ? 37.558  -27.120 15.395  1.00 103.40 ?  190 LYS   A HZ1  1 
ATOM   7875  H  HZ2  . LYS   B 1 191 ? 36.496  -26.301 15.945  1.00 103.40 ?  190 LYS   A HZ2  1 
ATOM   7876  H  HZ3  . LYS   B 1 191 ? 36.922  -27.498 16.641  1.00 103.40 ?  190 LYS   A HZ3  1 
ATOM   7877  N  N    . THR   B 1 192 ? 34.933  -32.806 18.895  1.00 95.20  ?  191 THR   A N    1 
ATOM   7878  C  CA   . THR   B 1 192 ? 35.240  -34.231 18.981  1.00 108.70 ?  191 THR   A CA   1 
ATOM   7879  C  C    . THR   B 1 192 ? 34.977  -34.783 20.375  1.00 114.67 ?  191 THR   A C    1 
ATOM   7880  O  O    . THR   B 1 192 ? 34.129  -35.662 20.535  1.00 106.99 ?  191 THR   A O    1 
ATOM   7881  C  CB   . THR   B 1 192 ? 36.703  -34.493 18.572  1.00 109.11 ?  191 THR   A CB   1 
ATOM   7882  O  OG1  . THR   B 1 192 ? 36.807  -34.516 17.139  1.00 107.33 ?  191 THR   A OG1  1 
ATOM   7883  C  CG2  . THR   B 1 192 ? 37.202  -35.832 19.142  1.00 121.00 ?  191 THR   A CG2  1 
ATOM   7884  H  H    . THR   B 1 192 ? 35.471  -32.316 19.352  1.00 114.24 ?  191 THR   A H    1 
ATOM   7885  H  HA   . THR   B 1 192 ? 34.669  -34.704 18.356  1.00 130.44 ?  191 THR   A HA   1 
ATOM   7886  H  HB   . THR   B 1 192 ? 37.265  -33.787 18.926  1.00 130.93 ?  191 THR   A HB   1 
ATOM   7887  H  HG1  . THR   B 1 192 ? 36.354  -33.891 16.808  1.00 128.80 ?  191 THR   A HG1  1 
ATOM   7888  H  HG21 . THR   B 1 192 ? 37.988  -36.127 18.655  1.00 145.20 ?  191 THR   A HG21 1 
ATOM   7889  H  HG22 . THR   B 1 192 ? 37.432  -35.728 20.078  1.00 145.20 ?  191 THR   A HG22 1 
ATOM   7890  H  HG23 . THR   B 1 192 ? 36.509  -36.506 19.060  1.00 145.20 ?  191 THR   A HG23 1 
ATOM   7891  N  N    . CYS   B 1 193 ? 35.677  -34.289 21.406  1.00 112.06 ?  192 CYS   A N    1 
ATOM   7892  C  CA   . CYS   B 1 193 ? 35.524  -34.858 22.746  1.00 101.98 ?  192 CYS   A CA   1 
ATOM   7893  C  C    . CYS   B 1 193 ? 34.194  -34.478 23.394  1.00 93.29  ?  192 CYS   A C    1 
ATOM   7894  O  O    . CYS   B 1 193 ? 33.737  -35.186 24.295  1.00 82.95  ?  192 CYS   A O    1 
ATOM   7895  C  CB   . CYS   B 1 193 ? 36.711  -34.455 23.627  1.00 96.47  ?  192 CYS   A CB   1 
ATOM   7896  S  SG   . CYS   B 1 193 ? 37.596  -32.993 23.059  1.00 116.16 ?  192 CYS   A SG   1 
ATOM   7897  H  H    . CYS   B 1 193 ? 36.236  -33.637 21.355  1.00 134.47 ?  192 CYS   A H    1 
ATOM   7898  H  HA   . CYS   B 1 193 ? 35.536  -35.826 22.682  1.00 122.38 ?  192 CYS   A HA   1 
ATOM   7899  H  HB2  . CYS   B 1 193 ? 36.383  -34.271 24.522  1.00 115.76 ?  192 CYS   A HB2  1 
ATOM   7900  H  HB3  . CYS   B 1 193 ? 37.342  -35.191 23.651  1.00 115.76 ?  192 CYS   A HB3  1 
ATOM   7901  H  HG   . CYS   B 1 193 ? 37.187  -32.033 23.652  1.00 139.39 ?  192 CYS   A HG   1 
ATOM   7902  N  N    . GLY   B 1 194 ? 33.550  -33.405 22.951  1.00 100.59 ?  193 GLY   A N    1 
ATOM   7903  C  CA   . GLY   B 1 194 ? 32.141  -33.188 23.232  1.00 64.64  ?  193 GLY   A CA   1 
ATOM   7904  C  C    . GLY   B 1 194 ? 31.867  -32.260 24.407  1.00 67.31  ?  193 GLY   A C    1 
ATOM   7905  O  O    . GLY   B 1 194 ? 32.766  -31.683 25.031  1.00 67.97  ?  193 GLY   A O    1 
ATOM   7906  H  H    . GLY   B 1 194 ? 33.913  -32.783 22.480  1.00 120.71 ?  193 GLY   A H    1 
ATOM   7907  H  HA2  . GLY   B 1 194 ? 31.721  -32.804 22.447  1.00 77.57  ?  193 GLY   A HA2  1 
ATOM   7908  H  HA3  . GLY   B 1 194 ? 31.726  -34.043 23.427  1.00 77.57  ?  193 GLY   A HA3  1 
ATOM   7909  N  N    . GLN   B 1 195 ? 30.572  -32.159 24.713  1.00 56.09  ?  194 GLN   A N    1 
ATOM   7910  C  CA   . GLN   B 1 195 ? 30.077  -31.251 25.740  1.00 53.42  ?  194 GLN   A CA   1 
ATOM   7911  C  C    . GLN   B 1 195 ? 30.370  -31.744 27.160  1.00 59.37  ?  194 GLN   A C    1 
ATOM   7912  O  O    . GLN   B 1 195 ? 30.260  -32.934 27.473  1.00 58.82  ?  194 GLN   A O    1 
ATOM   7913  C  CB   . GLN   B 1 195 ? 28.570  -31.062 25.551  1.00 52.48  ?  194 GLN   A CB   1 
ATOM   7914  C  CG   . GLN   B 1 195 ? 27.888  -30.818 26.822  1.00 73.72  ?  194 GLN   A CG   1 
ATOM   7915  C  CD   . GLN   B 1 195 ? 26.525  -30.081 26.662  1.00 71.00  ?  194 GLN   A CD   1 
ATOM   7916  O  OE1  . GLN   B 1 195 ? 26.248  -29.489 25.619  1.00 68.62  ?  194 GLN   A OE1  1 
ATOM   7917  N  NE2  . GLN   B 1 195 ? 25.693  -30.099 27.727  1.00 68.09  ?  194 GLN   A NE2  1 
ATOM   7918  H  H    . GLN   B 1 195 ? 29.950  -32.615 24.333  1.00 67.31  ?  194 GLN   A H    1 
ATOM   7919  H  HA   . GLN   B 1 195 ? 30.532  -30.399 25.649  1.00 64.10  ?  194 GLN   A HA   1 
ATOM   7920  H  HB2  . GLN   B 1 195 ? 28.414  -30.301 24.971  1.00 62.97  ?  194 GLN   A HB2  1 
ATOM   7921  H  HB3  . GLN   B 1 195 ? 28.195  -31.864 25.154  1.00 62.97  ?  194 GLN   A HB3  1 
ATOM   7922  H  HG2  . GLN   B 1 195 ? 27.717  -31.670 27.254  1.00 88.46  ?  194 GLN   A HG2  1 
ATOM   7923  H  HG3  . GLN   B 1 195 ? 28.459  -30.270 27.383  1.00 88.46  ?  194 GLN   A HG3  1 
ATOM   7924  H  HE21 . GLN   B 1 195 ? 25.926  -30.506 28.448  1.00 81.71  ?  194 GLN   A HE21 1 
ATOM   7925  H  HE22 . GLN   B 1 195 ? 24.930  -29.705 27.683  1.00 81.71  ?  194 GLN   A HE22 1 
ATOM   7926  N  N    . GLN   B 1 196 ? 30.683  -30.793 28.041  1.00 54.70  ?  195 GLN   A N    1 
ATOM   7927  C  CA   . GLN   B 1 196 ? 30.962  -31.083 29.441  1.00 50.81  ?  195 GLN   A CA   1 
ATOM   7928  C  C    . GLN   B 1 196 ? 30.542  -29.893 30.292  1.00 54.00  ?  195 GLN   A C    1 
ATOM   7929  O  O    . GLN   B 1 196 ? 31.083  -28.790 30.135  1.00 45.96  ?  195 GLN   A O    1 
ATOM   7930  C  CB   . GLN   B 1 196 ? 32.448  -31.385 29.678  1.00 50.28  ?  195 GLN   A CB   1 
ATOM   7931  C  CG   . GLN   B 1 196 ? 32.830  -31.467 31.172  1.00 49.37  ?  195 GLN   A CG   1 
ATOM   7932  C  CD   . GLN   B 1 196 ? 32.448  -32.804 31.866  1.00 61.21  ?  195 GLN   A CD   1 
ATOM   7933  O  OE1  . GLN   B 1 196 ? 32.015  -32.814 33.028  1.00 57.42  ?  195 GLN   A OE1  1 
ATOM   7934  N  NE2  . GLN   B 1 196 ? 32.582  -33.925 31.140  1.00 70.76  ?  195 GLN   A NE2  1 
ATOM   7935  H  H    . GLN   B 1 196 ? 30.740  -29.957 27.845  1.00 65.64  ?  195 GLN   A H    1 
ATOM   7936  H  HA   . GLN   B 1 196 ? 30.439  -31.859 29.698  1.00 60.97  ?  195 GLN   A HA   1 
ATOM   7937  H  HB2  . GLN   B 1 196 ? 32.663  -32.238 29.269  1.00 60.33  ?  195 GLN   A HB2  1 
ATOM   7938  H  HB3  . GLN   B 1 196 ? 32.978  -30.680 29.274  1.00 60.33  ?  195 GLN   A HB3  1 
ATOM   7939  H  HG2  . GLN   B 1 196 ? 33.791  -31.361 31.252  1.00 59.24  ?  195 GLN   A HG2  1 
ATOM   7940  H  HG3  . GLN   B 1 196 ? 32.377  -30.752 31.647  1.00 59.24  ?  195 GLN   A HG3  1 
ATOM   7941  H  HE21 . GLN   B 1 196 ? 32.868  -33.881 30.330  1.00 84.91  ?  195 GLN   A HE21 1 
ATOM   7942  H  HE22 . GLN   B 1 196 ? 32.382  -34.687 31.485  1.00 84.91  ?  195 GLN   A HE22 1 
ATOM   7943  N  N    . GLN   B 1 197 ? 29.651  -30.143 31.249  1.00 40.90  ?  196 GLN   A N    1 
ATOM   7944  C  CA   . GLN   B 1 197 ? 29.098  -29.116 32.105  1.00 40.56  ?  196 GLN   A CA   1 
ATOM   7945  C  C    . GLN   B 1 197 ? 29.639  -29.229 33.526  1.00 41.59  ?  196 GLN   A C    1 
ATOM   7946  O  O    . GLN   B 1 197 ? 29.931  -30.329 34.006  1.00 48.16  ?  196 GLN   A O    1 
ATOM   7947  C  CB   . GLN   B 1 197 ? 27.586  -29.253 32.122  1.00 33.86  ?  196 GLN   A CB   1 
ATOM   7948  C  CG   . GLN   B 1 197 ? 26.914  -28.066 32.714  1.00 34.43  ?  196 GLN   A CG   1 
ATOM   7949  C  CD   . GLN   B 1 197 ? 25.422  -28.256 32.618  1.00 44.17  ?  196 GLN   A CD   1 
ATOM   7950  O  OE1  . GLN   B 1 197 ? 24.782  -27.974 31.571  1.00 37.56  ?  196 GLN   A OE1  1 
ATOM   7951  N  NE2  . GLN   B 1 197 ? 24.848  -28.742 33.716  1.00 33.36  ?  196 GLN   A NE2  1 
ATOM   7952  H  H    . GLN   B 1 197 ? 29.347  -30.928 31.422  1.00 49.09  ?  196 GLN   A H    1 
ATOM   7953  H  HA   . GLN   B 1 197 ? 29.347  -28.239 31.774  1.00 48.67  ?  196 GLN   A HA   1 
ATOM   7954  H  HB2  . GLN   B 1 197 ? 27.267  -29.358 31.212  1.00 40.63  ?  196 GLN   A HB2  1 
ATOM   7955  H  HB3  . GLN   B 1 197 ? 27.345  -30.031 32.650  1.00 40.63  ?  196 GLN   A HB3  1 
ATOM   7956  H  HG2  . GLN   B 1 197 ? 27.162  -27.976 33.647  1.00 41.32  ?  196 GLN   A HG2  1 
ATOM   7957  H  HG3  . GLN   B 1 197 ? 27.163  -27.267 32.224  1.00 41.32  ?  196 GLN   A HG3  1 
ATOM   7958  H  HE21 . GLN   B 1 197 ? 25.326  -28.922 34.408  1.00 40.04  ?  196 GLN   A HE21 1 
ATOM   7959  H  HE22 . GLN   B 1 197 ? 23.999  -28.877 33.734  1.00 40.04  ?  196 GLN   A HE22 1 
ATOM   7960  N  N    . THR   B 1 198 ? 29.776  -28.085 34.204  1.00 29.82  ?  197 THR   A N    1 
ATOM   7961  C  CA   . THR   B 1 198 ? 30.177  -28.098 35.614  1.00 37.92  ?  197 THR   A CA   1 
ATOM   7962  C  C    . THR   B 1 198 ? 29.402  -27.045 36.414  1.00 36.59  ?  197 THR   A C    1 
ATOM   7963  O  O    . THR   B 1 198 ? 28.913  -26.041 35.896  1.00 37.65  ?  197 THR   A O    1 
ATOM   7964  C  CB   . THR   B 1 198 ? 31.714  -27.905 35.781  1.00 46.51  ?  197 THR   A CB   1 
ATOM   7965  O  OG1  . THR   B 1 198 ? 32.151  -26.700 35.134  1.00 46.59  ?  197 THR   A OG1  1 
ATOM   7966  C  CG2  . THR   B 1 198 ? 32.490  -29.090 35.158  1.00 43.45  ?  197 THR   A CG2  1 
ATOM   7967  H  H    . THR   B 1 198 ? 29.645  -27.301 33.875  1.00 35.78  ?  197 THR   A H    1 
ATOM   7968  H  HA   . THR   B 1 198 ? 29.937  -28.960 35.990  1.00 45.51  ?  197 THR   A HA   1 
ATOM   7969  H  HB   . THR   B 1 198 ? 31.907  -27.854 36.731  1.00 55.81  ?  197 THR   A HB   1 
ATOM   7970  H  HG1  . THR   B 1 198 ? 31.690  -26.560 34.446  1.00 55.90  ?  197 THR   A HG1  1 
ATOM   7971  H  HG21 . THR   B 1 198 ? 33.423  -29.051 35.423  1.00 52.14  ?  197 THR   A HG21 1 
ATOM   7972  H  HG22 . THR   B 1 198 ? 32.112  -29.931 35.462  1.00 52.14  ?  197 THR   A HG22 1 
ATOM   7973  H  HG23 . THR   B 1 198 ? 32.435  -29.051 34.191  1.00 52.14  ?  197 THR   A HG23 1 
ATOM   7974  N  N    . THR   B 1 199 ? 29.260  -27.289 37.697  1.00 38.08  ?  198 THR   A N    1 
ATOM   7975  C  CA   . THR   B 1 199 ? 28.548  -26.369 38.571  1.00 40.09  ?  198 THR   A CA   1 
ATOM   7976  C  C    . THR   B 1 199 ? 29.454  -25.915 39.705  1.00 42.12  ?  198 THR   A C    1 
ATOM   7977  O  O    . THR   B 1 199 ? 30.059  -26.743 40.387  1.00 47.32  ?  198 THR   A O    1 
ATOM   7978  C  CB   . THR   B 1 199 ? 27.305  -27.029 39.151  1.00 42.39  ?  198 THR   A CB   1 
ATOM   7979  O  OG1  . THR   B 1 199 ? 26.425  -27.402 38.097  1.00 40.01  ?  198 THR   A OG1  1 
ATOM   7980  C  CG2  . THR   B 1 199 ? 26.556  -26.075 40.065  1.00 46.95  ?  198 THR   A CG2  1 
ATOM   7981  H  H    . THR   B 1 199 ? 29.569  -27.986 38.094  1.00 45.69  ?  198 THR   A H    1 
ATOM   7982  H  HA   . THR   B 1 199 ? 28.289  -25.588 38.058  1.00 48.11  ?  198 THR   A HA   1 
ATOM   7983  H  HB   . THR   B 1 199 ? 27.578  -27.808 39.660  1.00 50.86  ?  198 THR   A HB   1 
ATOM   7984  H  HG1  . THR   B 1 199 ? 26.316  -26.756 37.571  1.00 48.01  ?  198 THR   A HG1  1 
ATOM   7985  H  HG21 . THR   B 1 199 ? 25.701  -26.459 40.315  1.00 56.34  ?  198 THR   A HG21 1 
ATOM   7986  H  HG22 . THR   B 1 199 ? 27.074  -25.910 40.868  1.00 56.34  ?  198 THR   A HG22 1 
ATOM   7987  H  HG23 . THR   B 1 199 ? 26.402  -25.232 39.610  1.00 56.34  ?  198 THR   A HG23 1 
ATOM   7988  N  N    . LEU   B 1 200 ? 29.537  -24.603 39.902  1.00 43.46  ?  199 LEU   A N    1 
ATOM   7989  C  CA   . LEU   B 1 200 ? 30.242  -23.979 41.009  1.00 41.31  ?  199 LEU   A CA   1 
ATOM   7990  C  C    . LEU   B 1 200 ? 29.264  -23.240 41.923  1.00 42.68  ?  199 LEU   A C    1 
ATOM   7991  O  O    . LEU   B 1 200 ? 28.156  -22.811 41.511  1.00 33.75  ?  199 LEU   A O    1 
ATOM   7992  C  CB   . LEU   B 1 200 ? 31.285  -22.990 40.503  1.00 38.78  ?  199 LEU   A CB   1 
ATOM   7993  C  CG   . LEU   B 1 200 ? 32.100  -23.455 39.304  1.00 49.83  ?  199 LEU   A CG   1 
ATOM   7994  C  CD1  . LEU   B 1 200 ? 32.734  -22.293 38.517  1.00 46.32  ?  199 LEU   A CD1  1 
ATOM   7995  C  CD2  . LEU   B 1 200 ? 33.222  -24.415 39.773  1.00 44.44  ?  199 LEU   A CD2  1 
ATOM   7996  H  H    . LEU   B 1 200 ? 29.172  -24.026 39.379  1.00 52.15  ?  199 LEU   A H    1 
ATOM   7997  H  HA   . LEU   B 1 200 ? 30.685  -24.671 41.524  1.00 49.57  ?  199 LEU   A HA   1 
ATOM   7998  H  HB2  . LEU   B 1 200 ? 30.830  -22.173 40.244  1.00 46.54  ?  199 LEU   A HB2  1 
ATOM   7999  H  HB3  . LEU   B 1 200 ? 31.908  -22.808 41.224  1.00 46.54  ?  199 LEU   A HB3  1 
ATOM   8000  H  HG   . LEU   B 1 200 ? 31.490  -23.910 38.702  1.00 59.80  ?  199 LEU   A HG   1 
ATOM   8001  H  HD11 . LEU   B 1 200 ? 33.195  -22.651 37.742  1.00 55.58  ?  199 LEU   A HD11 1 
ATOM   8002  H  HD12 . LEU   B 1 200 ? 32.033  -21.685 38.233  1.00 55.58  ?  199 LEU   A HD12 1 
ATOM   8003  H  HD13 . LEU   B 1 200 ? 33.362  -21.828 39.091  1.00 55.58  ?  199 LEU   A HD13 1 
ATOM   8004  H  HD21 . LEU   B 1 200 ? 33.858  -24.533 39.051  1.00 53.33  ?  199 LEU   A HD21 1 
ATOM   8005  H  HD22 . LEU   B 1 200 ? 33.665  -24.029 40.545  1.00 53.33  ?  199 LEU   A HD22 1 
ATOM   8006  H  HD23 . LEU   B 1 200 ? 32.828  -25.269 40.009  1.00 53.33  ?  199 LEU   A HD23 1 
ATOM   8007  N  N    . LYS   B 1 201 ? 29.696  -23.092 43.180  1.00 41.76  ?  200 LYS   A N    1 
ATOM   8008  C  CA   . LYS   B 1 201 ? 28.891  -22.449 44.213  1.00 40.82  ?  200 LYS   A CA   1 
ATOM   8009  C  C    . LYS   B 1 201 ? 29.778  -21.580 45.077  1.00 41.89  ?  200 LYS   A C    1 
ATOM   8010  O  O    . LYS   B 1 201 ? 31.000  -21.733 45.097  1.00 49.05  ?  200 LYS   A O    1 
ATOM   8011  C  CB   . LYS   B 1 201 ? 28.169  -23.464 45.084  1.00 37.28  ?  200 LYS   A CB   1 
ATOM   8012  C  CG   . LYS   B 1 201 ? 27.586  -24.602 44.293  1.00 42.14  ?  200 LYS   A CG   1 
ATOM   8013  C  CD   . LYS   B 1 201 ? 26.063  -24.664 44.407  1.00 51.95  ?  200 LYS   A CD   1 
ATOM   8014  C  CE   . LYS   B 1 201 ? 25.539  -25.966 43.794  1.00 56.33  ?  200 LYS   A CE   1 
ATOM   8015  N  NZ   . LYS   B 1 201 ? 24.776  -26.815 44.758  1.00 66.25  ?  200 LYS   A NZ   1 
ATOM   8016  H  H    . LYS   B 1 201 ? 30.463  -23.362 43.459  1.00 50.12  ?  200 LYS   A H    1 
ATOM   8017  H  HA   . LYS   B 1 201 ? 28.229  -21.884 43.785  1.00 48.98  ?  200 LYS   A HA   1 
ATOM   8018  H  HB2  . LYS   B 1 201 ? 28.796  -23.834 45.724  1.00 44.74  ?  200 LYS   A HB2  1 
ATOM   8019  H  HB3  . LYS   B 1 201 ? 27.443  -23.020 45.550  1.00 44.74  ?  200 LYS   A HB3  1 
ATOM   8020  H  HG2  . LYS   B 1 201 ? 27.814  -24.490 43.357  1.00 50.57  ?  200 LYS   A HG2  1 
ATOM   8021  H  HG3  . LYS   B 1 201 ? 27.948  -25.439 44.624  1.00 50.57  ?  200 LYS   A HG3  1 
ATOM   8022  H  HD2  . LYS   B 1 201 ? 25.805  -24.635 45.342  1.00 62.34  ?  200 LYS   A HD2  1 
ATOM   8023  H  HD3  . LYS   B 1 201 ? 25.670  -23.916 43.931  1.00 62.34  ?  200 LYS   A HD3  1 
ATOM   8024  H  HE2  . LYS   B 1 201 ? 24.946  -25.748 43.057  1.00 67.60  ?  200 LYS   A HE2  1 
ATOM   8025  H  HE3  . LYS   B 1 201 ? 26.292  -26.486 43.472  1.00 67.60  ?  200 LYS   A HE3  1 
ATOM   8026  H  HZ1  . LYS   B 1 201 ? 24.489  -27.553 44.352  1.00 79.50  ?  200 LYS   A HZ1  1 
ATOM   8027  H  HZ2  . LYS   B 1 201 ? 25.299  -27.045 45.440  1.00 79.50  ?  200 LYS   A HZ2  1 
ATOM   8028  H  HZ3  . LYS   B 1 201 ? 24.075  -26.365 45.070  1.00 79.50  ?  200 LYS   A HZ3  1 
ATOM   8029  N  N    . GLY   B 1 202 ? 29.151  -20.641 45.780  1.00 41.29  ?  201 GLY   A N    1 
ATOM   8030  C  CA   . GLY   B 1 202 ? 29.954  -19.833 46.668  1.00 41.74  ?  201 GLY   A CA   1 
ATOM   8031  C  C    . GLY   B 1 202 ? 30.857  -18.877 45.904  1.00 39.35  ?  201 GLY   A C    1 
ATOM   8032  O  O    . GLY   B 1 202 ? 30.559  -18.409 44.801  1.00 44.08  ?  201 GLY   A O    1 
ATOM   8033  H  H    . GLY   B 1 202 ? 28.309  -20.467 45.758  1.00 49.55  ?  201 GLY   A H    1 
ATOM   8034  H  HA2  . GLY   B 1 202 ? 29.373  -19.312 47.245  1.00 50.09  ?  201 GLY   A HA2  1 
ATOM   8035  H  HA3  . GLY   B 1 202 ? 30.509  -20.409 47.217  1.00 50.09  ?  201 GLY   A HA3  1 
ATOM   8036  N  N    . VAL   B 1 203 ? 32.020  -18.623 46.480  1.00 45.09  ?  202 VAL   A N    1 
ATOM   8037  C  CA   . VAL   B 1 203 ? 32.901  -17.618 45.909  1.00 43.31  ?  202 VAL   A CA   1 
ATOM   8038  C  C    . VAL   B 1 203 ? 33.426  -18.040 44.524  1.00 42.53  ?  202 VAL   A C    1 
ATOM   8039  O  O    . VAL   B 1 203 ? 33.686  -17.190 43.662  1.00 36.58  ?  202 VAL   A O    1 
ATOM   8040  C  CB   . VAL   B 1 203 ? 34.028  -17.319 46.909  1.00 47.57  ?  202 VAL   A CB   1 
ATOM   8041  C  CG1  . VAL   B 1 203 ? 34.865  -18.563 47.206  1.00 57.40  ?  202 VAL   A CG1  1 
ATOM   8042  C  CG2  . VAL   B 1 203 ? 34.870  -16.220 46.341  1.00 48.48  ?  202 VAL   A CG2  1 
ATOM   8043  H  H    . VAL   B 1 203 ? 32.317  -19.010 47.188  1.00 54.10  ?  202 VAL   A H    1 
ATOM   8044  H  HA   . VAL   B 1 203 ? 32.399  -16.802 45.760  1.00 51.97  ?  202 VAL   A HA   1 
ATOM   8045  H  HB   . VAL   B 1 203 ? 33.652  -17.041 47.759  1.00 57.09  ?  202 VAL   A HB   1 
ATOM   8046  H  HG11 . VAL   B 1 203 ? 35.488  -18.360 47.922  1.00 68.88  ?  202 VAL   A HG11 1 
ATOM   8047  H  HG12 . VAL   B 1 203 ? 34.275  -19.284 47.476  1.00 68.88  ?  202 VAL   A HG12 1 
ATOM   8048  H  HG13 . VAL   B 1 203 ? 35.351  -18.815 46.406  1.00 68.88  ?  202 VAL   A HG13 1 
ATOM   8049  H  HG21 . VAL   B 1 203 ? 35.478  -15.900 47.026  1.00 58.18  ?  202 VAL   A HG21 1 
ATOM   8050  H  HG22 . VAL   B 1 203 ? 35.374  -16.565 45.587  1.00 58.18  ?  202 VAL   A HG22 1 
ATOM   8051  H  HG23 . VAL   B 1 203 ? 34.292  -15.497 46.049  1.00 58.18  ?  202 VAL   A HG23 1 
ATOM   8052  N  N    . GLU   B 1 204 ? 33.548  -19.334 44.257  1.00 32.61  ?  203 GLU   A N    1 
ATOM   8053  C  CA   . GLU   B 1 204 ? 33.938  -19.751 42.922  1.00 42.47  ?  203 GLU   A CA   1 
ATOM   8054  C  C    . GLU   B 1 204 ? 32.879  -19.359 41.900  1.00 41.70  ?  203 GLU   A C    1 
ATOM   8055  O  O    . GLU   B 1 204 ? 33.193  -19.269 40.717  1.00 35.45  ?  203 GLU   A O    1 
ATOM   8056  C  CB   . GLU   B 1 204 ? 34.198  -21.260 42.881  1.00 53.62  ?  203 GLU   A CB   1 
ATOM   8057  C  CG   . GLU   B 1 204 ? 35.156  -21.821 43.965  1.00 67.52  ?  203 GLU   A CG   1 
ATOM   8058  C  CD   . GLU   B 1 204 ? 34.610  -21.711 45.394  1.00 91.70  ?  203 GLU   A CD   1 
ATOM   8059  O  OE1  . GLU   B 1 204 ? 33.371  -21.842 45.570  1.00 109.46 ?  203 GLU   A OE1  1 
ATOM   8060  O  OE2  . GLU   B 1 204 ? 35.359  -21.346 46.318  1.00 190.58 ?  203 GLU   A OE2  1 
ATOM   8061  H  H    . GLU   B 1 204 ? 33.413  -19.972 44.817  1.00 39.14  ?  203 GLU   A H    1 
ATOM   8062  H  HA   . GLU   B 1 204 ? 34.773  -19.320 42.680  1.00 50.96  ?  203 GLU   A HA   1 
ATOM   8063  H  HB2  . GLU   B 1 204 ? 33.348  -21.716 42.987  1.00 64.35  ?  203 GLU   A HB2  1 
ATOM   8064  H  HB3  . GLU   B 1 204 ? 34.585  -21.477 42.018  1.00 64.35  ?  203 GLU   A HB3  1 
ATOM   8065  H  HG2  . GLU   B 1 204 ? 35.317  -22.760 43.783  1.00 81.03  ?  203 GLU   A HG2  1 
ATOM   8066  H  HG3  . GLU   B 1 204 ? 35.990  -21.329 43.929  1.00 81.03  ?  203 GLU   A HG3  1 
ATOM   8067  N  N    . ALA   B 1 205 ? 31.629  -19.122 42.331  1.00 35.58  ?  204 ALA   A N    1 
ATOM   8068  C  CA   . ALA   B 1 205 ? 30.568  -18.804 41.392  1.00 31.08  ?  204 ALA   A CA   1 
ATOM   8069  C  C    . ALA   B 1 205 ? 30.516  -17.326 41.020  1.00 31.76  ?  204 ALA   A C    1 
ATOM   8070  O  O    . ALA   B 1 205 ? 29.775  -16.961 40.113  1.00 34.27  ?  204 ALA   A O    1 
ATOM   8071  C  CB   . ALA   B 1 205 ? 29.180  -19.236 41.934  1.00 32.90  ?  204 ALA   A CB   1 
ATOM   8072  H  H    . ALA   B 1 205 ? 31.384  -19.142 43.155  1.00 42.69  ?  204 ALA   A H    1 
ATOM   8073  H  HA   . ALA   B 1 205 ? 30.733  -19.316 40.585  1.00 37.30  ?  204 ALA   A HA   1 
ATOM   8074  H  HB1  . ALA   B 1 205 ? 28.560  -19.311 41.191  1.00 39.48  ?  204 ALA   A HB1  1 
ATOM   8075  H  HB2  . ALA   B 1 205 ? 29.267  -20.093 42.380  1.00 39.48  ?  204 ALA   A HB2  1 
ATOM   8076  H  HB3  . ALA   B 1 205 ? 28.864  -18.567 42.562  1.00 39.48  ?  204 ALA   A HB3  1 
ATOM   8077  N  N    . VAL   B 1 206 ? 31.264  -16.453 41.679  1.00 29.56  ?  205 VAL   A N    1 
ATOM   8078  C  CA   . VAL   B 1 206 ? 31.191  -15.039 41.367  1.00 27.81  ?  205 VAL   A CA   1 
ATOM   8079  C  C    . VAL   B 1 206 ? 32.518  -14.467 40.912  1.00 29.74  ?  205 VAL   A C    1 
ATOM   8080  O  O    . VAL   B 1 206 ? 32.589  -13.263 40.607  1.00 32.36  ?  205 VAL   A O    1 
ATOM   8081  C  CB   . VAL   B 1 206 ? 30.647  -14.231 42.561  1.00 36.17  ?  205 VAL   A CB   1 
ATOM   8082  C  CG1  . VAL   B 1 206 ? 29.302  -14.780 43.038  1.00 31.67  ?  205 VAL   A CG1  1 
ATOM   8083  C  CG2  . VAL   B 1 206 ? 31.598  -14.214 43.711  1.00 31.80  ?  205 VAL   A CG2  1 
ATOM   8084  H  H    . VAL   B 1 206 ? 31.816  -16.657 42.306  1.00 35.48  ?  205 VAL   A H    1 
ATOM   8085  H  HA   . VAL   B 1 206 ? 30.572  -14.928 40.629  1.00 33.38  ?  205 VAL   A HA   1 
ATOM   8086  H  HB   . VAL   B 1 206 ? 30.529  -13.321 42.247  1.00 43.41  ?  205 VAL   A HB   1 
ATOM   8087  H  HG11 . VAL   B 1 206 ? 28.918  -14.163 43.680  1.00 38.01  ?  205 VAL   A HG11 1 
ATOM   8088  H  HG12 . VAL   B 1 206 ? 28.710  -14.874 42.274  1.00 38.01  ?  205 VAL   A HG12 1 
ATOM   8089  H  HG13 . VAL   B 1 206 ? 29.443  -15.645 43.454  1.00 38.01  ?  205 VAL   A HG13 1 
ATOM   8090  H  HG21 . VAL   B 1 206 ? 31.201  -13.716 44.442  1.00 38.16  ?  205 VAL   A HG21 1 
ATOM   8091  H  HG22 . VAL   B 1 206 ? 31.774  -15.126 43.989  1.00 38.16  ?  205 VAL   A HG22 1 
ATOM   8092  H  HG23 . VAL   B 1 206 ? 32.424  -13.789 43.431  1.00 38.16  ?  205 VAL   A HG23 1 
ATOM   8093  N  N    . MET   B 1 207 ? 33.587  -15.252 40.775  1.00 31.88  ?  206 MET   A N    1 
ATOM   8094  C  CA   . MET   B 1 207 ? 34.864  -14.691 40.376  1.00 31.32  ?  206 MET   A CA   1 
ATOM   8095  C  C    . MET   B 1 207 ? 35.422  -15.495 39.211  1.00 29.87  ?  206 MET   A C    1 
ATOM   8096  O  O    . MET   B 1 207 ? 35.290  -16.718 39.179  1.00 31.63  ?  206 MET   A O    1 
ATOM   8097  C  CB   . MET   B 1 207 ? 35.854  -14.726 41.544  1.00 30.00  ?  206 MET   A CB   1 
ATOM   8098  C  CG   . MET   B 1 207 ? 35.287  -14.239 42.868  1.00 37.48  ?  206 MET   A CG   1 
ATOM   8099  S  SD   . MET   B 1 207 ? 36.568  -13.704 44.018  1.00 49.33  ?  206 MET   A SD   1 
ATOM   8100  C  CE   . MET   B 1 207 ? 37.495  -15.223 44.221  1.00 50.42  ?  206 MET   A CE   1 
ATOM   8101  H  H    . MET   B 1 207 ? 33.620  -16.104 40.850  1.00 38.26  ?  206 MET   A H    1 
ATOM   8102  H  HA   . MET   B 1 207 ? 34.719  -13.755 40.128  1.00 37.58  ?  206 MET   A HA   1 
ATOM   8103  H  HB2  . MET   B 1 207 ? 36.154  -15.639 41.671  1.00 36.00  ?  206 MET   A HB2  1 
ATOM   8104  H  HB3  . MET   B 1 207 ? 36.612  -14.161 41.324  1.00 36.00  ?  206 MET   A HB3  1 
ATOM   8105  H  HG2  . MET   B 1 207 ? 34.697  -13.487 42.703  1.00 44.98  ?  206 MET   A HG2  1 
ATOM   8106  H  HG3  . MET   B 1 207 ? 34.794  -14.963 43.285  1.00 44.98  ?  206 MET   A HG3  1 
ATOM   8107  H  HE1  . MET   B 1 207 ? 38.406  -15.071 43.958  1.00 60.51  ?  206 MET   A HE1  1 
ATOM   8108  H  HE2  . MET   B 1 207 ? 37.460  -15.490 45.142  1.00 60.51  ?  206 MET   A HE2  1 
ATOM   8109  H  HE3  . MET   B 1 207 ? 37.104  -15.903 43.667  1.00 60.51  ?  206 MET   A HE3  1 
ATOM   8110  N  N    . TYR   B 1 208 ? 36.043  -14.816 38.253  1.00 32.32  ?  207 TYR   A N    1 
ATOM   8111  C  CA   . TYR   B 1 208 ? 36.619  -15.501 37.114  1.00 38.10  ?  207 TYR   A CA   1 
ATOM   8112  C  C    . TYR   B 1 208 ? 37.947  -14.838 36.766  1.00 37.95  ?  207 TYR   A C    1 
ATOM   8113  O  O    . TYR   B 1 208 ? 38.052  -13.612 36.777  1.00 31.72  ?  207 TYR   A O    1 
ATOM   8114  C  CB   . TYR   B 1 208 ? 35.676  -15.451 35.913  1.00 31.87  ?  207 TYR   A CB   1 
ATOM   8115  C  CG   . TYR   B 1 208 ? 36.108  -16.342 34.770  1.00 34.23  ?  207 TYR   A CG   1 
ATOM   8116  C  CD1  . TYR   B 1 208 ? 35.758  -17.685 34.739  1.00 39.52  ?  207 TYR   A CD1  1 
ATOM   8117  C  CD2  . TYR   B 1 208 ? 36.872  -15.840 33.725  1.00 38.55  ?  207 TYR   A CD2  1 
ATOM   8118  C  CE1  . TYR   B 1 208 ? 36.153  -18.503 33.697  1.00 49.37  ?  207 TYR   A CE1  1 
ATOM   8119  C  CE2  . TYR   B 1 208 ? 37.272  -16.649 32.679  1.00 36.87  ?  207 TYR   A CE2  1 
ATOM   8120  C  CZ   . TYR   B 1 208 ? 36.910  -17.979 32.670  1.00 46.85  ?  207 TYR   A CZ   1 
ATOM   8121  O  OH   . TYR   B 1 208 ? 37.307  -18.788 31.630  1.00 49.34  ?  207 TYR   A OH   1 
ATOM   8122  H  H    . TYR   B 1 208 ? 36.157  -13.964 38.228  1.00 38.79  ?  207 TYR   A H    1 
ATOM   8123  H  HA   . TYR   B 1 208 ? 36.748  -16.441 37.361  1.00 45.71  ?  207 TYR   A HA   1 
ATOM   8124  H  HB2  . TYR   B 1 208 ? 34.791  -15.734 36.193  1.00 38.24  ?  207 TYR   A HB2  1 
ATOM   8125  H  HB3  . TYR   B 1 208 ? 35.641  -14.540 35.580  1.00 38.24  ?  207 TYR   A HB3  1 
ATOM   8126  H  HD1  . TYR   B 1 208 ? 35.248  -18.042 35.431  1.00 47.42  ?  207 TYR   A HD1  1 
ATOM   8127  H  HD2  . TYR   B 1 208 ? 37.117  -14.943 33.729  1.00 46.26  ?  207 TYR   A HD2  1 
ATOM   8128  H  HE1  . TYR   B 1 208 ? 35.911  -19.400 33.689  1.00 59.25  ?  207 TYR   A HE1  1 
ATOM   8129  H  HE2  . TYR   B 1 208 ? 37.782  -16.298 31.985  1.00 44.25  ?  207 TYR   A HE2  1 
ATOM   8130  H  HH   . TYR   B 1 208 ? 38.081  -18.617 31.421  1.00 59.21  ?  207 TYR   A HH   1 
ATOM   8131  N  N    . MET   B 1 209 ? 38.959  -15.641 36.457  1.00 34.39  ?  208 MET   A N    1 
ATOM   8132  C  CA   . MET   B 1 209 ? 40.264  -15.123 36.101  1.00 34.62  ?  208 MET   A CA   1 
ATOM   8133  C  C    . MET   B 1 209 ? 40.511  -15.490 34.643  1.00 26.22  ?  208 MET   A C    1 
ATOM   8134  O  O    . MET   B 1 209 ? 40.479  -16.611 34.305  1.00 33.73  ?  208 MET   A O    1 
ATOM   8135  C  CB   . MET   B 1 209 ? 41.358  -15.703 36.996  1.00 32.25  ?  208 MET   A CB   1 
ATOM   8136  C  CG   . MET   B 1 209 ? 42.747  -15.097 36.812  1.00 29.40  ?  208 MET   A CG   1 
ATOM   8137  S  SD   . MET   B 1 209 ? 42.717  -13.338 37.023  1.00 38.09  ?  208 MET   A SD   1 
ATOM   8138  C  CE   . MET   B 1 209 ? 44.366  -12.757 36.964  1.00 37.79  ?  208 MET   A CE   1 
ATOM   8139  H  H    . MET   B 1 209 ? 38.935  -16.498 36.396  1.00 41.27  ?  208 MET   A H    1 
ATOM   8140  H  HA   . MET   B 1 209 ? 40.259  -14.152 36.231  1.00 41.54  ?  208 MET   A HA   1 
ATOM   8141  H  HB2  . MET   B 1 209 ? 41.100  -15.564 37.921  1.00 38.70  ?  208 MET   A HB2  1 
ATOM   8142  H  HB3  . MET   B 1 209 ? 41.429  -16.654 36.818  1.00 38.70  ?  208 MET   A HB3  1 
ATOM   8143  H  HG2  . MET   B 1 209 ? 43.348  -15.471 37.475  1.00 35.28  ?  208 MET   A HG2  1 
ATOM   8144  H  HG3  . MET   B 1 209 ? 43.068  -15.292 35.918  1.00 35.28  ?  208 MET   A HG3  1 
ATOM   8145  H  HE1  . MET   B 1 209 ? 44.359  -11.799 36.904  1.00 45.34  ?  208 MET   A HE1  1 
ATOM   8146  H  HE2  . MET   B 1 209 ? 44.820  -13.032 37.764  1.00 45.34  ?  208 MET   A HE2  1 
ATOM   8147  H  HE3  . MET   B 1 209 ? 44.802  -13.133 36.197  1.00 45.34  ?  208 MET   A HE3  1 
ATOM   8148  N  N    . GLY   B 1 210 ? 40.754  -14.548 33.773  1.00 28.95  ?  209 GLY   A N    1 
ATOM   8149  C  CA   . GLY   B 1 210 ? 40.949  -14.868 32.380  1.00 33.85  ?  209 GLY   A CA   1 
ATOM   8150  C  C    . GLY   B 1 210 ? 40.375  -13.881 31.381  1.00 36.82  ?  209 GLY   A C    1 
ATOM   8151  O  O    . GLY   B 1 210 ? 40.879  -13.703 30.303  1.00 32.72  ?  209 GLY   A O    1 
ATOM   8152  H  H    . GLY   B 1 210 ? 40.844  -13.711 33.954  1.00 34.74  ?  209 GLY   A H    1 
ATOM   8153  H  HA2  . GLY   B 1 210 ? 41.901  -14.941 32.209  1.00 40.62  ?  209 GLY   A HA2  1 
ATOM   8154  H  HA3  . GLY   B 1 210 ? 40.549  -15.734 32.201  1.00 40.62  ?  209 GLY   A HA3  1 
ATOM   8155  N  N    . THR   B 1 211 ? 39.295  -13.238 31.738  1.00 33.73  ?  210 THR   A N    1 
ATOM   8156  C  CA   . THR   B 1 211 ? 38.712  -12.243 30.862  1.00 26.37  ?  210 THR   A CA   1 
ATOM   8157  C  C    . THR   B 1 211 ? 37.919  -11.247 31.677  1.00 28.50  ?  210 THR   A C    1 
ATOM   8158  O  O    . THR   B 1 211 ? 37.313  -11.583 32.695  1.00 32.86  ?  210 THR   A O    1 
ATOM   8159  C  CB   . THR   B 1 211 ? 37.800  -12.897 29.838  1.00 34.95  ?  210 THR   A CB   1 
ATOM   8160  O  OG1  . THR   B 1 211 ? 37.141  -11.905 29.038  1.00 38.29  ?  210 THR   A OG1  1 
ATOM   8161  C  CG2  . THR   B 1 211 ? 36.741  -13.656 30.582  1.00 36.89  ?  210 THR   A CG2  1 
ATOM   8162  H  H    . THR   B 1 211 ? 38.898  -13.339 32.495  1.00 40.47  ?  210 THR   A H    1 
ATOM   8163  H  HA   . THR   B 1 211 ? 39.421  -11.762 30.407  1.00 31.64  ?  210 THR   A HA   1 
ATOM   8164  H  HB   . THR   B 1 211 ? 38.317  -13.477 29.258  1.00 41.94  ?  210 THR   A HB   1 
ATOM   8165  H  HG1  . THR   B 1 211 ? 36.571  -12.270 28.541  1.00 45.95  ?  210 THR   A HG1  1 
ATOM   8166  H  HG21 . THR   B 1 211 ? 36.129  -14.074 29.956  1.00 44.27  ?  210 THR   A HG21 1 
ATOM   8167  H  HG22 . THR   B 1 211 ? 37.149  -14.344 31.130  1.00 44.27  ?  210 THR   A HG22 1 
ATOM   8168  H  HG23 . THR   B 1 211 ? 36.241  -13.053 31.155  1.00 44.27  ?  210 THR   A HG23 1 
ATOM   8169  N  N    . LEU   B 1 212 ? 37.926  -10.024 31.206  1.00 26.18  ?  211 LEU   A N    1 
ATOM   8170  C  CA   . LEU   B 1 212 ? 37.222  -8.956  31.861  1.00 26.72  ?  211 LEU   A CA   1 
ATOM   8171  C  C    . LEU   B 1 212 ? 35.788  -8.860  31.404  1.00 28.38  ?  211 LEU   A C    1 
ATOM   8172  O  O    . LEU   B 1 212 ? 34.982  -8.247  32.101  1.00 27.28  ?  211 LEU   A O    1 
ATOM   8173  C  CB   . LEU   B 1 212 ? 37.900  -7.622  31.569  1.00 25.33  ?  211 LEU   A CB   1 
ATOM   8174  C  CG   . LEU   B 1 212 ? 39.346  -7.462  32.083  1.00 27.96  ?  211 LEU   A CG   1 
ATOM   8175  C  CD1  . LEU   B 1 212 ? 39.909  -6.182  31.490  1.00 31.10  ?  211 LEU   A CD1  1 
ATOM   8176  C  CD2  . LEU   B 1 212 ? 39.377  -7.371  33.603  1.00 31.52  ?  211 LEU   A CD2  1 
ATOM   8177  H  H    . LEU   B 1 212 ? 38.341  -9.782  30.493  1.00 31.41  ?  211 LEU   A H    1 
ATOM   8178  H  HA   . LEU   B 1 212 ? 37.244  -9.107  32.819  1.00 32.07  ?  211 LEU   A HA   1 
ATOM   8179  H  HB2  . LEU   B 1 212 ? 37.924  -7.500  30.607  1.00 30.39  ?  211 LEU   A HB2  1 
ATOM   8180  H  HB3  . LEU   B 1 212 ? 37.372  -6.919  31.979  1.00 30.39  ?  211 LEU   A HB3  1 
ATOM   8181  H  HG   . LEU   B 1 212 ? 39.880  -8.229  31.823  1.00 33.55  ?  211 LEU   A HG   1 
ATOM   8182  H  HD11 . LEU   B 1 212 ? 40.302  -5.652  32.201  1.00 37.33  ?  211 LEU   A HD11 1 
ATOM   8183  H  HD12 . LEU   B 1 212 ? 40.586  -6.409  30.834  1.00 37.33  ?  211 LEU   A HD12 1 
ATOM   8184  H  HD13 . LEU   B 1 212 ? 39.190  -5.688  31.067  1.00 37.33  ?  211 LEU   A HD13 1 
ATOM   8185  H  HD21 . LEU   B 1 212 ? 40.253  -7.064  33.884  1.00 37.82  ?  211 LEU   A HD21 1 
ATOM   8186  H  HD22 . LEU   B 1 212 ? 38.698  -6.743  33.896  1.00 37.82  ?  211 LEU   A HD22 1 
ATOM   8187  H  HD23 . LEU   B 1 212 ? 39.198  -8.248  33.976  1.00 37.82  ?  211 LEU   A HD23 1 
ATOM   8188  N  N    . SER   B 1 213 ? 35.458  -9.402  30.236  1.00 28.38  ?  212 SER   A N    1 
ATOM   8189  C  CA   . SER   B 1 213 ? 34.176  -9.110  29.607  1.00 29.33  ?  212 SER   A CA   1 
ATOM   8190  C  C    . SER   B 1 213 ? 33.162  -10.166 30.024  1.00 32.17  ?  212 SER   A C    1 
ATOM   8191  O  O    . SER   B 1 213 ? 33.382  -11.370 29.806  1.00 28.03  ?  212 SER   A O    1 
ATOM   8192  C  CB   . SER   B 1 213 ? 34.273  -9.069  28.079  1.00 29.70  ?  212 SER   A CB   1 
ATOM   8193  O  OG   . SER   B 1 213 ? 32.982  -9.167  27.468  1.00 31.81  ?  212 SER   A OG   1 
ATOM   8194  H  H    . SER   B 1 213 ? 35.959  -9.940  29.790  1.00 34.06  ?  212 SER   A H    1 
ATOM   8195  H  HA   . SER   B 1 213 ? 33.887  -8.236  29.911  1.00 35.20  ?  212 SER   A HA   1 
ATOM   8196  H  HB2  . SER   B 1 213 ? 34.683  -8.231  27.813  1.00 35.64  ?  212 SER   A HB2  1 
ATOM   8197  H  HB3  . SER   B 1 213 ? 34.818  -9.814  27.779  1.00 35.64  ?  212 SER   A HB3  1 
ATOM   8198  H  HG   . SER   B 1 213 ? 32.494  -8.533  27.724  1.00 38.17  ?  212 SER   A HG   1 
ATOM   8199  N  N    . TYR   B 1 214 ? 32.051  -9.708  30.629  1.00 27.12  ?  213 TYR   A N    1 
ATOM   8200  C  CA   . TYR   B 1 214 ? 30.947  -10.613 30.949  1.00 31.17  ?  213 TYR   A CA   1 
ATOM   8201  C  C    . TYR   B 1 214 ? 30.279  -11.092 29.673  1.00 30.41  ?  213 TYR   A C    1 
ATOM   8202  O  O    . TYR   B 1 214 ? 30.002  -12.290 29.531  1.00 29.77  ?  213 TYR   A O    1 
ATOM   8203  C  CB   . TYR   B 1 214 ? 29.995  -9.897  31.898  1.00 32.64  ?  213 TYR   A CB   1 
ATOM   8204  C  CG   . TYR   B 1 214 ? 29.010  -10.776 32.626  1.00 24.69  ?  213 TYR   A CG   1 
ATOM   8205  C  CD1  . TYR   B 1 214 ? 29.288  -12.086 32.904  1.00 27.71  ?  213 TYR   A CD1  1 
ATOM   8206  C  CD2  . TYR   B 1 214 ? 27.783  -10.259 33.040  1.00 32.94  ?  213 TYR   A CD2  1 
ATOM   8207  C  CE1  . TYR   B 1 214 ? 28.393  -12.882 33.534  1.00 30.78  ?  213 TYR   A CE1  1 
ATOM   8208  C  CE2  . TYR   B 1 214 ? 26.860  -11.043 33.706  1.00 31.31  ?  213 TYR   A CE2  1 
ATOM   8209  C  CZ   . TYR   B 1 214 ? 27.167  -12.352 33.942  1.00 33.01  ?  213 TYR   A CZ   1 
ATOM   8210  O  OH   . TYR   B 1 214 ? 26.270  -13.123 34.590  1.00 33.29  ?  213 TYR   A OH   1 
ATOM   8211  H  H    . TYR   B 1 214 ? 31.919  -8.890  30.858  1.00 32.55  ?  213 TYR   A H    1 
ATOM   8212  H  HA   . TYR   B 1 214 ? 31.258  -11.408 31.411  1.00 37.40  ?  213 TYR   A HA   1 
ATOM   8213  H  HB2  . TYR   B 1 214 ? 30.524  -9.440  32.571  1.00 39.16  ?  213 TYR   A HB2  1 
ATOM   8214  H  HB3  . TYR   B 1 214 ? 29.482  -9.254  31.385  1.00 39.16  ?  213 TYR   A HB3  1 
ATOM   8215  H  HD1  . TYR   B 1 214 ? 30.111  -12.438 32.653  1.00 33.26  ?  213 TYR   A HD1  1 
ATOM   8216  H  HD2  . TYR   B 1 214 ? 27.581  -9.368  32.865  1.00 39.52  ?  213 TYR   A HD2  1 
ATOM   8217  H  HE1  . TYR   B 1 214 ? 28.594  -13.776 33.695  1.00 36.93  ?  213 TYR   A HE1  1 
ATOM   8218  H  HE2  . TYR   B 1 214 ? 26.047  -10.687 33.986  1.00 37.58  ?  213 TYR   A HE2  1 
ATOM   8219  H  HH   . TYR   B 1 214 ? 26.014  -12.739 35.292  1.00 39.95  ?  213 TYR   A HH   1 
ATOM   8220  N  N    . GLU   B 1 215 ? 30.158  -10.214 28.672  1.00 29.94  ?  214 GLU   A N    1 
ATOM   8221  C  CA   . GLU   B 1 215 ? 29.580  -10.655 27.400  1.00 34.17  ?  214 GLU   A CA   1 
ATOM   8222  C  C    . GLU   B 1 215 ? 30.414  -11.763 26.757  1.00 31.68  ?  214 GLU   A C    1 
ATOM   8223  O  O    . GLU   B 1 215 ? 29.876  -12.787 26.315  1.00 28.01  ?  214 GLU   A O    1 
ATOM   8224  C  CB   . GLU   B 1 215 ? 29.424  -9.467  26.453  1.00 34.01  ?  214 GLU   A CB   1 
ATOM   8225  C  CG   . GLU   B 1 215 ? 28.320  -8.518  26.888  1.00 43.07  ?  214 GLU   A CG   1 
ATOM   8226  C  CD   . GLU   B 1 215 ? 27.025  -9.252  27.293  1.00 51.61  ?  214 GLU   A CD   1 
ATOM   8227  O  OE1  . GLU   B 1 215 ? 26.356  -9.829  26.414  1.00 56.20  ?  214 GLU   A OE1  1 
ATOM   8228  O  OE2  . GLU   B 1 215 ? 26.664  -9.266  28.485  1.00 53.75  ?  214 GLU   A OE2  1 
ATOM   8229  H  H    . GLU   B 1 215 ? 30.394  -9.388  28.703  1.00 35.93  ?  214 GLU   A H    1 
ATOM   8230  H  HA   . GLU   B 1 215 ? 28.697  -11.016 27.573  1.00 41.00  ?  214 GLU   A HA   1 
ATOM   8231  H  HB2  . GLU   B 1 215 ? 30.257  -8.970  26.429  1.00 40.82  ?  214 GLU   A HB2  1 
ATOM   8232  H  HB3  . GLU   B 1 215 ? 29.208  -9.795  25.566  1.00 40.82  ?  214 GLU   A HB3  1 
ATOM   8233  H  HG2  . GLU   B 1 215 ? 28.626  -8.007  27.653  1.00 51.68  ?  214 GLU   A HG2  1 
ATOM   8234  H  HG3  . GLU   B 1 215 ? 28.108  -7.921  26.153  1.00 51.68  ?  214 GLU   A HG3  1 
ATOM   8235  N  N    . GLN   B 1 216 ? 31.738  -11.587 26.696  1.00 34.04  ?  215 GLN   A N    1 
ATOM   8236  C  CA   . GLN   B 1 216 ? 32.562  -12.637 26.095  1.00 33.67  ?  215 GLN   A CA   1 
ATOM   8237  C  C    . GLN   B 1 216 ? 32.321  -13.988 26.780  1.00 33.04  ?  215 GLN   A C    1 
ATOM   8238  O  O    . GLN   B 1 216 ? 32.126  -15.018 26.108  1.00 32.86  ?  215 GLN   A O    1 
ATOM   8239  C  CB   . GLN   B 1 216 ? 34.047  -12.244 26.133  1.00 39.13  ?  215 GLN   A CB   1 
ATOM   8240  C  CG   . GLN   B 1 216 ? 34.908  -12.968 25.109  1.00 42.27  ?  215 GLN   A CG   1 
ATOM   8241  C  CD   . GLN   B 1 216 ? 34.304  -13.052 23.690  1.00 50.24  ?  215 GLN   A CD   1 
ATOM   8242  O  OE1  . GLN   B 1 216 ? 33.898  -12.039 23.076  1.00 52.83  ?  215 GLN   A OE1  1 
ATOM   8243  N  NE2  . GLN   B 1 216 ? 34.259  -14.273 23.162  1.00 45.32  ?  215 GLN   A NE2  1 
ATOM   8244  H  H    . GLN   B 1 216 ? 32.165  -10.898 26.984  1.00 40.84  ?  215 GLN   A H    1 
ATOM   8245  H  HA   . GLN   B 1 216 ? 32.317  -12.734 25.161  1.00 40.40  ?  215 GLN   A HA   1 
ATOM   8246  H  HB2  . GLN   B 1 216 ? 34.121  -11.292 25.959  1.00 46.95  ?  215 GLN   A HB2  1 
ATOM   8247  H  HB3  . GLN   B 1 216 ? 34.401  -12.448 27.013  1.00 46.95  ?  215 GLN   A HB3  1 
ATOM   8248  H  HG2  . GLN   B 1 216 ? 35.756  -12.503 25.036  1.00 50.73  ?  215 GLN   A HG2  1 
ATOM   8249  H  HG3  . GLN   B 1 216 ? 35.053  -13.877 25.417  1.00 50.73  ?  215 GLN   A HG3  1 
ATOM   8250  H  HE21 . GLN   B 1 216 ? 34.555  -14.946 23.609  1.00 54.39  ?  215 GLN   A HE21 1 
ATOM   8251  H  HE22 . GLN   B 1 216 ? 33.934  -14.389 22.375  1.00 54.39  ?  215 GLN   A HE22 1 
ATOM   8252  N  N    . PHE   B 1 217 ? 32.317  -13.986 28.120  1.00 28.15  ?  216 PHE   A N    1 
ATOM   8253  C  CA   . PHE   B 1 217 ? 32.013  -15.178 28.910  1.00 27.69  ?  216 PHE   A CA   1 
ATOM   8254  C  C    . PHE   B 1 217 ? 30.672  -15.784 28.519  1.00 32.92  ?  216 PHE   A C    1 
ATOM   8255  O  O    . PHE   B 1 217 ? 30.513  -17.007 28.540  1.00 36.38  ?  216 PHE   A O    1 
ATOM   8256  C  CB   . PHE   B 1 217 ? 32.016  -14.781 30.395  1.00 29.72  ?  216 PHE   A CB   1 
ATOM   8257  C  CG   . PHE   B 1 217 ? 32.223  -15.899 31.340  1.00 31.84  ?  216 PHE   A CG   1 
ATOM   8258  C  CD1  . PHE   B 1 217 ? 33.085  -16.928 31.037  1.00 37.29  ?  216 PHE   A CD1  1 
ATOM   8259  C  CD2  . PHE   B 1 217 ? 31.584  -15.885 32.585  1.00 32.77  ?  216 PHE   A CD2  1 
ATOM   8260  C  CE1  . PHE   B 1 217 ? 33.294  -17.951 31.939  1.00 45.85  ?  216 PHE   A CE1  1 
ATOM   8261  C  CE2  . PHE   B 1 217 ? 31.777  -16.913 33.494  1.00 38.48  ?  216 PHE   A CE2  1 
ATOM   8262  C  CZ   . PHE   B 1 217 ? 32.632  -17.948 33.179  1.00 44.54  ?  216 PHE   A CZ   1 
ATOM   8263  H  H    . PHE   B 1 217 ? 32.490  -13.295 28.601  1.00 33.78  ?  216 PHE   A H    1 
ATOM   8264  H  HA   . PHE   B 1 217 ? 32.688  -15.857 28.755  1.00 33.23  ?  216 PHE   A HA   1 
ATOM   8265  H  HB2  . PHE   B 1 217 ? 32.731  -14.142 30.540  1.00 35.66  ?  216 PHE   A HB2  1 
ATOM   8266  H  HB3  . PHE   B 1 217 ? 31.161  -14.376 30.607  1.00 35.66  ?  216 PHE   A HB3  1 
ATOM   8267  H  HD1  . PHE   B 1 217 ? 33.529  -16.934 30.220  1.00 44.75  ?  216 PHE   A HD1  1 
ATOM   8268  H  HD2  . PHE   B 1 217 ? 31.023  -15.177 32.805  1.00 39.33  ?  216 PHE   A HD2  1 
ATOM   8269  H  HE1  . PHE   B 1 217 ? 33.876  -18.644 31.726  1.00 55.02  ?  216 PHE   A HE1  1 
ATOM   8270  H  HE2  . PHE   B 1 217 ? 31.334  -16.904 34.311  1.00 46.18  ?  216 PHE   A HE2  1 
ATOM   8271  H  HZ   . PHE   B 1 217 ? 32.769  -18.641 33.784  1.00 53.45  ?  216 PHE   A HZ   1 
ATOM   8272  N  N    . LYS   B 1 218 ? 29.670  -14.946 28.234  1.00 30.71  ?  217 LYS   A N    1 
ATOM   8273  C  CA   . LYS   B 1 218 ? 28.387  -15.472 27.785  1.00 33.34  ?  217 LYS   A CA   1 
ATOM   8274  C  C    . LYS   B 1 218 ? 28.474  -16.013 26.371  1.00 32.57  ?  217 LYS   A C    1 
ATOM   8275  O  O    . LYS   B 1 218 ? 27.853  -17.033 26.056  1.00 32.66  ?  217 LYS   A O    1 
ATOM   8276  C  CB   . LYS   B 1 218 ? 27.331  -14.390 27.874  1.00 34.36  ?  217 LYS   A CB   1 
ATOM   8277  C  CG   . LYS   B 1 218 ? 27.039  -13.960 29.316  1.00 34.40  ?  217 LYS   A CG   1 
ATOM   8278  C  CD   . LYS   B 1 218 ? 26.382  -12.566 29.379  1.00 38.08  ?  217 LYS   A CD   1 
ATOM   8279  C  CE   . LYS   B 1 218 ? 25.702  -12.372 30.724  1.00 38.27  ?  217 LYS   A CE   1 
ATOM   8280  N  NZ   . LYS   B 1 218 ? 24.828  -11.148 30.771  1.00 39.83  ?  217 LYS   A NZ   1 
ATOM   8281  H  H    . LYS   B 1 218 ? 29.710  -14.089 28.292  1.00 36.85  ?  217 LYS   A H    1 
ATOM   8282  H  HA   . LYS   B 1 218 ? 28.127  -16.202 28.368  1.00 40.01  ?  217 LYS   A HA   1 
ATOM   8283  H  HB2  . LYS   B 1 218 ? 27.637  -13.610 27.385  1.00 41.23  ?  217 LYS   A HB2  1 
ATOM   8284  H  HB3  . LYS   B 1 218 ? 26.506  -14.722 27.486  1.00 41.23  ?  217 LYS   A HB3  1 
ATOM   8285  H  HG2  . LYS   B 1 218 ? 26.433  -14.599 29.723  1.00 41.28  ?  217 LYS   A HG2  1 
ATOM   8286  H  HG3  . LYS   B 1 218 ? 27.870  -13.926 29.814  1.00 41.28  ?  217 LYS   A HG3  1 
ATOM   8287  H  HD2  . LYS   B 1 218 ? 27.059  -11.881 29.271  1.00 45.70  ?  217 LYS   A HD2  1 
ATOM   8288  H  HD3  . LYS   B 1 218 ? 25.715  -12.487 28.680  1.00 45.70  ?  217 LYS   A HD3  1 
ATOM   8289  H  HE2  . LYS   B 1 218 ? 25.145  -13.144 30.910  1.00 45.93  ?  217 LYS   A HE2  1 
ATOM   8290  H  HE3  . LYS   B 1 218 ? 26.382  -12.279 31.410  1.00 45.93  ?  217 LYS   A HE3  1 
ATOM   8291  H  HZ1  . LYS   B 1 218 ? 24.589  -10.977 31.611  1.00 47.80  ?  217 LYS   A HZ1  1 
ATOM   8292  H  HZ2  . LYS   B 1 218 ? 25.269  -10.446 30.448  1.00 47.80  ?  217 LYS   A HZ2  1 
ATOM   8293  H  HZ3  . LYS   B 1 218 ? 24.095  -11.279 30.283  1.00 47.80  ?  217 LYS   A HZ3  1 
ATOM   8294  N  N    . LYS   B 1 219 ? 29.253  -15.386 25.520  1.00 36.63  ?  218 LYS   A N    1 
ATOM   8295  C  CA   . LYS   B 1 219 ? 29.371  -15.840 24.149  1.00 40.98  ?  218 LYS   A CA   1 
ATOM   8296  C  C    . LYS   B 1 219 ? 30.264  -17.022 23.991  1.00 36.00  ?  218 LYS   A C    1 
ATOM   8297  O  O    . LYS   B 1 219 ? 30.033  -17.832 23.155  1.00 40.37  ?  218 LYS   A O    1 
ATOM   8298  C  CB   . LYS   B 1 219 ? 29.860  -14.731 23.247  1.00 35.88  ?  218 LYS   A CB   1 
ATOM   8299  C  CG   . LYS   B 1 219 ? 28.786  -13.749 22.909  1.00 40.07  ?  218 LYS   A CG   1 
ATOM   8300  C  CD   . LYS   B 1 219 ? 29.350  -12.383 22.618  1.00 51.55  ?  218 LYS   A CD   1 
ATOM   8301  C  CE   . LYS   B 1 219 ? 28.458  -11.586 21.694  1.00 61.57  ?  218 LYS   A CE   1 
ATOM   8302  N  NZ   . LYS   B 1 219 ? 29.209  -11.074 20.512  1.00 65.03  ?  218 LYS   A NZ   1 
ATOM   8303  H  H    . LYS   B 1 219 ? 29.727  -14.694 25.708  1.00 43.95  ?  218 LYS   A H    1 
ATOM   8304  H  HA   . LYS   B 1 219 ? 28.481  -16.102 23.834  1.00 49.18  ?  218 LYS   A HA   1 
ATOM   8305  H  HB2  . LYS   B 1 219 ? 30.577  -14.252 23.692  1.00 43.06  ?  218 LYS   A HB2  1 
ATOM   8306  H  HB3  . LYS   B 1 219 ? 30.183  -15.118 22.418  1.00 43.06  ?  218 LYS   A HB3  1 
ATOM   8307  H  HG2  . LYS   B 1 219 ? 28.309  -14.055 22.121  1.00 48.09  ?  218 LYS   A HG2  1 
ATOM   8308  H  HG3  . LYS   B 1 219 ? 28.177  -13.671 23.660  1.00 48.09  ?  218 LYS   A HG3  1 
ATOM   8309  H  HD2  . LYS   B 1 219 ? 29.441  -11.891 23.449  1.00 61.86  ?  218 LYS   A HD2  1 
ATOM   8310  H  HD3  . LYS   B 1 219 ? 30.216  -12.481 22.192  1.00 61.86  ?  218 LYS   A HD3  1 
ATOM   8311  H  HE2  . LYS   B 1 219 ? 27.740  -12.155 21.375  1.00 73.89  ?  218 LYS   A HE2  1 
ATOM   8312  H  HE3  . LYS   B 1 219 ? 28.095  -10.826 22.176  1.00 73.89  ?  218 LYS   A HE3  1 
ATOM   8313  H  HZ1  . LYS   B 1 219 ? 29.275  -10.117 20.554  1.00 78.04  ?  218 LYS   A HZ1  1 
ATOM   8314  H  HZ2  . LYS   B 1 219 ? 28.754  -11.319 19.703  1.00 78.04  ?  218 LYS   A HZ2  1 
ATOM   8315  H  HZ3  . LYS   B 1 219 ? 30.094  -11.447 20.497  1.00 78.04  ?  218 LYS   A HZ3  1 
ATOM   8316  N  N    . GLY   B 1 220 ? 31.269  -17.128 24.824  1.00 33.55  ?  219 GLY   A N    1 
ATOM   8317  C  CA   . GLY   B 1 220 ? 32.211  -18.224 24.727  1.00 35.41  ?  219 GLY   A CA   1 
ATOM   8318  C  C    . GLY   B 1 220 ? 33.615  -17.680 24.625  1.00 33.31  ?  219 GLY   A C    1 
ATOM   8319  O  O    . GLY   B 1 220 ? 33.872  -16.719 23.892  1.00 35.27  ?  219 GLY   A O    1 
ATOM   8320  H  H    . GLY   B 1 220 ? 31.438  -16.575 25.461  1.00 40.26  ?  219 GLY   A H    1 
ATOM   8321  H  HA2  . GLY   B 1 220 ? 32.145  -18.787 25.514  1.00 42.49  ?  219 GLY   A HA2  1 
ATOM   8322  H  HA3  . GLY   B 1 220 ? 32.019  -18.757 23.940  1.00 42.49  ?  219 GLY   A HA3  1 
ATOM   8323  N  N    . VAL   B 1 221 ? 34.515  -18.237 25.437  1.00 40.92  ?  220 VAL   A N    1 
ATOM   8324  C  CA   . VAL   B 1 221 ? 35.941  -17.931 25.395  1.00 42.99  ?  220 VAL   A CA   1 
ATOM   8325  C  C    . VAL   B 1 221 ? 36.656  -19.203 24.957  1.00 46.36  ?  220 VAL   A C    1 
ATOM   8326  O  O    . VAL   B 1 221 ? 36.247  -20.314 25.327  1.00 43.01  ?  220 VAL   A O    1 
ATOM   8327  C  CB   . VAL   B 1 221 ? 36.547  -17.484 26.746  1.00 40.19  ?  220 VAL   A CB   1 
ATOM   8328  C  CG1  . VAL   B 1 221 ? 35.900  -16.255 27.344  1.00 38.30  ?  220 VAL   A CG1  1 
ATOM   8329  C  CG2  . VAL   B 1 221 ? 36.440  -18.631 27.742  1.00 41.75  ?  220 VAL   A CG2  1 
ATOM   8330  H  H    . VAL   B 1 221 ? 34.315  -18.815 26.041  1.00 49.10  ?  220 VAL   A H    1 
ATOM   8331  H  HA   . VAL   B 1 221 ? 36.061  -17.202 24.766  1.00 51.58  ?  220 VAL   A HA   1 
ATOM   8332  H  HB   . VAL   B 1 221 ? 37.470  -17.245 26.570  1.00 48.23  ?  220 VAL   A HB   1 
ATOM   8333  H  HG11 . VAL   B 1 221 ? 36.468  -15.912 28.051  1.00 45.96  ?  220 VAL   A HG11 1 
ATOM   8334  H  HG12 . VAL   B 1 221 ? 35.793  -15.586 26.651  1.00 45.96  ?  220 VAL   A HG12 1 
ATOM   8335  H  HG13 . VAL   B 1 221 ? 35.033  -16.499 27.705  1.00 45.96  ?  220 VAL   A HG13 1 
ATOM   8336  H  HG21 . VAL   B 1 221 ? 36.304  -18.265 28.630  1.00 50.10  ?  220 VAL   A HG21 1 
ATOM   8337  H  HG22 . VAL   B 1 221 ? 35.690  -19.194 27.497  1.00 50.10  ?  220 VAL   A HG22 1 
ATOM   8338  H  HG23 . VAL   B 1 221 ? 37.262  -19.146 27.720  1.00 50.10  ?  220 VAL   A HG23 1 
ATOM   8339  N  N    . GLN   B 1 222 ? 37.765  -19.044 24.215  1.00 55.90  ?  221 GLN   A N    1 
ATOM   8340  C  CA   . GLN   B 1 222 ? 38.566  -20.187 23.766  1.00 51.74  ?  221 GLN   A CA   1 
ATOM   8341  C  C    . GLN   B 1 222 ? 39.566  -20.580 24.832  1.00 49.67  ?  221 GLN   A C    1 
ATOM   8342  O  O    . GLN   B 1 222 ? 40.253  -19.738 25.412  1.00 48.77  ?  221 GLN   A O    1 
ATOM   8343  C  CB   . GLN   B 1 222 ? 39.320  -19.874 22.474  1.00 58.53  ?  221 GLN   A CB   1 
ATOM   8344  C  CG   . GLN   B 1 222 ? 38.708  -20.520 21.271  1.00 49.33  ?  221 GLN   A CG   1 
ATOM   8345  C  CD   . GLN   B 1 222 ? 37.318  -20.027 21.063  1.00 53.20  ?  221 GLN   A CD   1 
ATOM   8346  O  OE1  . GLN   B 1 222 ? 36.350  -20.793 21.137  1.00 63.94  ?  221 GLN   A OE1  1 
ATOM   8347  N  NE2  . GLN   B 1 222 ? 37.185  -18.719 20.889  1.00 57.91  ?  221 GLN   A NE2  1 
ATOM   8348  H  H    . GLN   B 1 222 ? 38.071  -18.282 23.961  1.00 67.08  ?  221 GLN   A H    1 
ATOM   8349  H  HA   . GLN   B 1 222 ? 37.963  -20.929 23.603  1.00 62.08  ?  221 GLN   A HA   1 
ATOM   8350  H  HB2  . GLN   B 1 222 ? 39.317  -18.914 22.333  1.00 70.24  ?  221 GLN   A HB2  1 
ATOM   8351  H  HB3  . GLN   B 1 222 ? 40.232  -20.195 22.555  1.00 70.24  ?  221 GLN   A HB3  1 
ATOM   8352  H  HG2  . GLN   B 1 222 ? 39.234  -20.305 20.485  1.00 59.20  ?  221 GLN   A HG2  1 
ATOM   8353  H  HG3  . GLN   B 1 222 ? 38.680  -21.481 21.399  1.00 59.20  ?  221 GLN   A HG3  1 
ATOM   8354  H  HE21 . GLN   B 1 222 ? 37.879  -18.211 20.901  1.00 69.50  ?  221 GLN   A HE21 1 
ATOM   8355  H  HE22 . GLN   B 1 222 ? 36.406  -18.378 20.764  1.00 69.50  ?  221 GLN   A HE22 1 
ATOM   8356  N  N    . ILE   B 1 223 ? 39.643  -21.893 25.106  1.00 53.70  ?  222 ILE   A N    1 
ATOM   8357  C  CA   . ILE   B 1 223 ? 40.607  -22.422 26.048  1.00 56.10  ?  222 ILE   A CA   1 
ATOM   8358  C  C    . ILE   B 1 223 ? 41.147  -23.725 25.482  1.00 68.53  ?  222 ILE   A C    1 
ATOM   8359  O  O    . ILE   B 1 223 ? 40.484  -24.373 24.648  1.00 68.08  ?  222 ILE   A O    1 
ATOM   8360  C  CB   . ILE   B 1 223 ? 40.001  -22.669 27.445  1.00 57.54  ?  222 ILE   A CB   1 
ATOM   8361  C  CG1  . ILE   B 1 223 ? 39.001  -23.822 27.401  1.00 51.65  ?  222 ILE   A CG1  1 
ATOM   8362  C  CG2  . ILE   B 1 223 ? 39.315  -21.421 27.973  1.00 53.26  ?  222 ILE   A CG2  1 
ATOM   8363  C  CD1  . ILE   B 1 223 ? 38.382  -24.100 28.742  1.00 56.21  ?  222 ILE   A CD1  1 
ATOM   8364  H  H    . ILE   B 1 223 ? 39.139  -22.491 24.751  1.00 64.44  ?  222 ILE   A H    1 
ATOM   8365  H  HA   . ILE   B 1 223 ? 41.334  -21.789 26.154  1.00 67.32  ?  222 ILE   A HA   1 
ATOM   8366  H  HB   . ILE   B 1 223 ? 40.731  -22.901 28.041  1.00 69.05  ?  222 ILE   A HB   1 
ATOM   8367  H  HG12 . ILE   B 1 223 ? 38.289  -23.599 26.781  1.00 61.98  ?  222 ILE   A HG12 1 
ATOM   8368  H  HG13 . ILE   B 1 223 ? 39.457  -24.626 27.107  1.00 61.98  ?  222 ILE   A HG13 1 
ATOM   8369  H  HG21 . ILE   B 1 223 ? 39.043  -21.575 28.892  1.00 63.91  ?  222 ILE   A HG21 1 
ATOM   8370  H  HG22 . ILE   B 1 223 ? 39.936  -20.677 27.933  1.00 63.91  ?  222 ILE   A HG22 1 
ATOM   8371  H  HG23 . ILE   B 1 223 ? 38.537  -21.233 27.425  1.00 63.91  ?  222 ILE   A HG23 1 
ATOM   8372  H  HD11 . ILE   B 1 223 ? 37.760  -24.839 28.655  1.00 67.45  ?  222 ILE   A HD11 1 
ATOM   8373  H  HD12 . ILE   B 1 223 ? 39.083  -24.329 29.372  1.00 67.45  ?  222 ILE   A HD12 1 
ATOM   8374  H  HD13 . ILE   B 1 223 ? 37.913  -23.306 29.043  1.00 67.45  ?  222 ILE   A HD13 1 
ATOM   8375  N  N    . PRO   B 1 224 ? 42.342  -24.132 25.902  1.00 67.89  ?  223 PRO   A N    1 
ATOM   8376  C  CA   . PRO   B 1 224 ? 42.941  -25.353 25.340  1.00 76.08  ?  223 PRO   A CA   1 
ATOM   8377  C  C    . PRO   B 1 224 ? 42.192  -26.610 25.775  1.00 76.60  ?  223 PRO   A C    1 
ATOM   8378  O  O    . PRO   B 1 224 ? 41.899  -26.792 26.959  1.00 67.56  ?  223 PRO   A O    1 
ATOM   8379  C  CB   . PRO   B 1 224 ? 44.375  -25.329 25.885  1.00 70.49  ?  223 PRO   A CB   1 
ATOM   8380  C  CG   . PRO   B 1 224 ? 44.299  -24.476 27.132  1.00 59.32  ?  223 PRO   A CG   1 
ATOM   8381  C  CD   . PRO   B 1 224 ? 43.261  -23.438 26.829  1.00 62.19  ?  223 PRO   A CD   1 
ATOM   8382  H  HA   . PRO   B 1 224 ? 42.951  -25.308 24.371  1.00 91.30  ?  223 PRO   A HA   1 
ATOM   8383  N  N    . CYS   B 1 225 ? 41.882  -27.477 24.804  1.00 75.11  ?  224 CYS   A N    1 
ATOM   8384  C  CA   . CYS   B 1 225 ? 41.422  -28.838 25.076  1.00 82.93  ?  224 CYS   A CA   1 
ATOM   8385  C  C    . CYS   B 1 225 ? 42.405  -29.881 24.558  1.00 79.62  ?  224 CYS   A C    1 
ATOM   8386  O  O    . CYS   B 1 225 ? 43.257  -29.615 23.710  1.00 74.90  ?  224 CYS   A O    1 
ATOM   8387  C  CB   . CYS   B 1 225 ? 40.046  -29.147 24.467  1.00 74.48  ?  224 CYS   A CB   1 
ATOM   8388  S  SG   . CYS   B 1 225 ? 39.689  -30.877 24.605  1.00 81.45  ?  224 CYS   A SG   1 
ATOM   8389  N  N    . THR   B 1 226 ? 42.187  -31.104 25.043  1.00 84.98  ?  225 THR   A N    1 
ATOM   8390  C  CA   . THR   B 1 226 ? 43.072  -32.236 24.851  1.00 73.34  ?  225 THR   A CA   1 
ATOM   8391  C  C    . THR   B 1 226 ? 42.986  -32.845 23.462  1.00 72.11  ?  225 THR   A C    1 
ATOM   8392  O  O    . THR   B 1 226 ? 43.882  -33.599 23.089  1.00 75.03  ?  225 THR   A O    1 
ATOM   8393  C  CB   . THR   B 1 226 ? 42.757  -33.281 25.913  1.00 63.75  ?  225 THR   A CB   1 
ATOM   8394  O  OG1  . THR   B 1 226 ? 43.021  -32.724 27.208  1.00 78.53  ?  225 THR   A OG1  1 
ATOM   8395  C  CG2  . THR   B 1 226 ? 43.600  -34.503 25.711  1.00 61.88  ?  225 THR   A CG2  1 
ATOM   8396  N  N    . CYS   B 1 227 ? 41.954  -32.539 22.681  1.00 86.89  ?  226 CYS   A N    1 
ATOM   8397  C  CA   . CYS   B 1 227 ? 42.094  -32.685 21.235  1.00 98.15  ?  226 CYS   A CA   1 
ATOM   8398  C  C    . CYS   B 1 227 ? 43.314  -31.862 20.813  1.00 92.85  ?  226 CYS   A C    1 
ATOM   8399  O  O    . CYS   B 1 227 ? 43.846  -31.077 21.610  1.00 93.00  ?  226 CYS   A O    1 
ATOM   8400  C  CB   . CYS   B 1 227 ? 40.886  -32.165 20.431  1.00 95.68  ?  226 CYS   A CB   1 
ATOM   8401  S  SG   . CYS   B 1 227 ? 39.347  -33.040 20.569  1.00 97.44  ?  226 CYS   A SG   1 
ATOM   8402  H  H    . CYS   B 1 227 ? 41.189  -32.256 22.954  1.00 104.27 ?  226 CYS   A H    1 
ATOM   8403  H  HA   . CYS   B 1 227 ? 42.173  -33.631 21.034  1.00 117.78 ?  226 CYS   A HA   1 
ATOM   8404  H  HB2  . CYS   B 1 227 ? 40.714  -31.253 20.715  1.00 114.82 ?  226 CYS   A HB2  1 
ATOM   8405  H  HB3  . CYS   B 1 227 ? 41.130  -32.178 19.492  1.00 114.82 ?  226 CYS   A HB3  1 
ATOM   8406  H  HG   . CYS   B 1 227 ? 38.477  -32.382 20.069  1.00 116.93 ?  226 CYS   A HG   1 
ATOM   8407  N  N    . GLY   B 1 228 ? 43.713  -31.946 19.546  1.00 99.75  ?  227 GLY   A N    1 
ATOM   8408  C  CA   . GLY   B 1 228 ? 44.540  -30.890 18.989  1.00 99.40  ?  227 GLY   A CA   1 
ATOM   8409  C  C    . GLY   B 1 228 ? 43.799  -29.573 18.915  1.00 102.19 ?  227 GLY   A C    1 
ATOM   8410  O  O    . GLY   B 1 228 ? 44.416  -28.505 18.938  1.00 109.48 ?  227 GLY   A O    1 
ATOM   8411  H  H    . GLY   B 1 228 ? 43.523  -32.587 19.005  1.00 119.70 ?  227 GLY   A H    1 
ATOM   8412  H  HA2  . GLY   B 1 228 ? 45.327  -30.770 19.543  1.00 119.28 ?  227 GLY   A HA2  1 
ATOM   8413  H  HA3  . GLY   B 1 228 ? 44.820  -31.137 18.093  1.00 119.28 ?  227 GLY   A HA3  1 
ATOM   8414  N  N    . LYS   B 1 229 ? 42.468  -29.635 18.879  1.00 108.00 ?  228 LYS   A N    1 
ATOM   8415  C  CA   . LYS   B 1 229 ? 41.621  -28.466 18.729  1.00 101.63 ?  228 LYS   A CA   1 
ATOM   8416  C  C    . LYS   B 1 229 ? 41.466  -27.733 20.063  1.00 90.01  ?  228 LYS   A C    1 
ATOM   8417  O  O    . LYS   B 1 229 ? 41.782  -28.241 21.142  1.00 89.54  ?  228 LYS   A O    1 
ATOM   8418  C  CB   . LYS   B 1 229 ? 40.235  -28.854 18.209  1.00 87.77  ?  228 LYS   A CB   1 
ATOM   8419  C  CG   . LYS   B 1 229 ? 40.209  -29.911 17.124  1.00 104.11 ?  228 LYS   A CG   1 
ATOM   8420  C  CD   . LYS   B 1 229 ? 38.892  -29.866 16.336  1.00 110.73 ?  228 LYS   A CD   1 
ATOM   8421  C  CE   . LYS   B 1 229 ? 37.690  -30.098 17.250  1.00 122.16 ?  228 LYS   A CE   1 
ATOM   8422  N  NZ   . LYS   B 1 229 ? 37.518  -31.551 17.574  1.00 115.55 ?  228 LYS   A NZ   1 
ATOM   8423  H  H    . LYS   B 1 229 ? 42.022  -30.368 18.942  1.00 129.59 ?  228 LYS   A H    1 
ATOM   8424  H  HA   . LYS   B 1 229 ? 42.040  -27.872 18.086  1.00 121.96 ?  228 LYS   A HA   1 
ATOM   8425  H  HB2  . LYS   B 1 229 ? 39.716  -29.194 18.954  1.00 105.32 ?  228 LYS   A HB2  1 
ATOM   8426  H  HB3  . LYS   B 1 229 ? 39.814  -28.059 17.846  1.00 105.32 ?  228 LYS   A HB3  1 
ATOM   8427  H  HG2  . LYS   B 1 229 ? 40.941  -29.757 16.506  1.00 124.93 ?  228 LYS   A HG2  1 
ATOM   8428  H  HG3  . LYS   B 1 229 ? 40.295  -30.789 17.527  1.00 124.93 ?  228 LYS   A HG3  1 
ATOM   8429  H  HD2  . LYS   B 1 229 ? 38.796  -28.995 15.919  1.00 132.88 ?  228 LYS   A HD2  1 
ATOM   8430  H  HD3  . LYS   B 1 229 ? 38.898  -30.559 15.658  1.00 132.88 ?  228 LYS   A HD3  1 
ATOM   8431  H  HE2  . LYS   B 1 229 ? 37.821  -29.614 18.081  1.00 146.59 ?  228 LYS   A HE2  1 
ATOM   8432  H  HE3  . LYS   B 1 229 ? 36.885  -29.786 16.808  1.00 146.59 ?  228 LYS   A HE3  1 
ATOM   8433  H  HZ1  . LYS   B 1 229 ? 37.388  -31.654 18.448  1.00 138.66 ?  228 LYS   A HZ1  1 
ATOM   8434  H  HZ2  . LYS   B 1 229 ? 36.815  -31.878 17.137  1.00 138.66 ?  228 LYS   A HZ2  1 
ATOM   8435  H  HZ3  . LYS   B 1 229 ? 38.244  -32.004 17.333  1.00 138.66 ?  228 LYS   A HZ3  1 
ATOM   8436  N  N    . GLN   B 1 230 ? 40.951  -26.523 19.984  1.00 87.97  ?  229 GLN   A N    1 
ATOM   8437  C  CA   . GLN   B 1 230 ? 40.592  -25.761 21.167  1.00 80.72  ?  229 GLN   A CA   1 
ATOM   8438  C  C    . GLN   B 1 230 ? 39.081  -25.831 21.359  1.00 72.44  ?  229 GLN   A C    1 
ATOM   8439  O  O    . GLN   B 1 230 ? 38.314  -26.142 20.434  1.00 59.02  ?  229 GLN   A O    1 
ATOM   8440  C  CB   . GLN   B 1 230 ? 41.083  -24.314 21.059  1.00 79.67  ?  229 GLN   A CB   1 
ATOM   8441  C  CG   . GLN   B 1 230 ? 42.372  -24.092 21.884  1.00 78.98  ?  229 GLN   A CG   1 
ATOM   8442  C  CD   . GLN   B 1 230 ? 42.850  -22.652 21.851  1.00 71.08  ?  229 GLN   A CD   1 
ATOM   8443  O  OE1  . GLN   B 1 230 ? 42.431  -21.867 20.996  1.00 66.24  ?  229 GLN   A OE1  1 
ATOM   8444  N  NE2  . GLN   B 1 230 ? 43.739  -22.300 22.771  1.00 69.95  ?  229 GLN   A NE2  1 
ATOM   8445  H  H    . GLN   B 1 230 ? 40.795  -26.113 19.245  1.00 105.56 ?  229 GLN   A H    1 
ATOM   8446  H  HA   . GLN   B 1 230 ? 41.017  -26.131 21.956  1.00 96.87  ?  229 GLN   A HA   1 
ATOM   8447  H  HB2  . GLN   B 1 230 ? 41.275  -24.109 20.130  1.00 95.60  ?  229 GLN   A HB2  1 
ATOM   8448  H  HB3  . GLN   B 1 230 ? 40.397  -23.717 21.395  1.00 95.60  ?  229 GLN   A HB3  1 
ATOM   8449  H  HG2  . GLN   B 1 230 ? 42.200  -24.330 22.809  1.00 94.77  ?  229 GLN   A HG2  1 
ATOM   8450  H  HG3  . GLN   B 1 230 ? 43.078  -24.651 21.524  1.00 94.77  ?  229 GLN   A HG3  1 
ATOM   8451  H  HE21 . GLN   B 1 230 ? 44.015  -22.878 23.346  1.00 83.93  ?  229 GLN   A HE21 1 
ATOM   8452  H  HE22 . GLN   B 1 230 ? 44.040  -21.495 22.793  1.00 83.93  ?  229 GLN   A HE22 1 
ATOM   8453  N  N    . ALA   B 1 231 ? 38.662  -25.595 22.596  1.00 75.83  ?  230 ALA   A N    1 
ATOM   8454  C  CA   . ALA   B 1 231 ? 37.258  -25.694 22.952  1.00 64.03  ?  230 ALA   A CA   1 
ATOM   8455  C  C    . ALA   B 1 231 ? 36.729  -24.345 23.433  1.00 56.85  ?  230 ALA   A C    1 
ATOM   8456  O  O    . ALA   B 1 231 ? 37.471  -23.402 23.743  1.00 55.28  ?  230 ALA   A O    1 
ATOM   8457  C  CB   . ALA   B 1 231 ? 37.031  -26.766 24.030  1.00 62.26  ?  230 ALA   A CB   1 
ATOM   8458  H  H    . ALA   B 1 231 ? 39.178  -25.374 23.248  1.00 90.99  ?  230 ALA   A H    1 
ATOM   8459  H  HA   . ALA   B 1 231 ? 36.758  -25.945 22.160  1.00 76.83  ?  230 ALA   A HA   1 
ATOM   8460  H  HB1  . ALA   B 1 231 ? 36.133  -27.120 23.940  1.00 74.72  ?  230 ALA   A HB1  1 
ATOM   8461  H  HB2  . ALA   B 1 231 ? 37.680  -27.477 23.911  1.00 74.72  ?  230 ALA   A HB2  1 
ATOM   8462  H  HB3  . ALA   B 1 231 ? 37.141  -26.362 24.905  1.00 74.72  ?  230 ALA   A HB3  1 
ATOM   8463  N  N    . THR   B 1 232 ? 35.413  -24.279 23.535  1.00 49.98  ?  231 THR   A N    1 
ATOM   8464  C  CA   . THR   B 1 232 ? 34.718  -23.064 23.920  1.00 47.89  ?  231 THR   A CA   1 
ATOM   8465  C  C    . THR   B 1 232 ? 34.089  -23.251 25.299  1.00 47.32  ?  231 THR   A C    1 
ATOM   8466  O  O    . THR   B 1 232 ? 33.231  -24.116 25.495  1.00 48.31  ?  231 THR   A O    1 
ATOM   8467  C  CB   . THR   B 1 232 ? 33.698  -22.734 22.835  1.00 40.24  ?  231 THR   A CB   1 
ATOM   8468  O  OG1  . THR   B 1 232 ? 34.381  -22.183 21.710  1.00 54.95  ?  231 THR   A OG1  1 
ATOM   8469  C  CG2  . THR   B 1 232 ? 32.708  -21.740 23.288  1.00 50.46  ?  231 THR   A CG2  1 
ATOM   8470  H  H    . THR   B 1 232 ? 34.887  -24.942 23.383  1.00 59.98  ?  231 THR   A H    1 
ATOM   8471  H  HA   . THR   B 1 232 ? 35.327  -22.314 24.015  1.00 57.47  ?  231 THR   A HA   1 
ATOM   8472  H  HB   . THR   B 1 232 ? 33.227  -23.549 22.603  1.00 48.29  ?  231 THR   A HB   1 
ATOM   8473  H  HG1  . THR   B 1 232 ? 33.831  -21.995 21.104  1.00 65.94  ?  231 THR   A HG1  1 
ATOM   8474  H  HG21 . THR   B 1 232 ? 32.157  -21.456 22.541  1.00 60.56  ?  231 THR   A HG21 1 
ATOM   8475  H  HG22 . THR   B 1 232 ? 32.137  -22.127 23.970  1.00 60.56  ?  231 THR   A HG22 1 
ATOM   8476  H  HG23 . THR   B 1 232 ? 33.159  -20.965 23.657  1.00 60.56  ?  231 THR   A HG23 1 
ATOM   8477  N  N    . LYS   B 1 233 ? 34.440  -22.407 26.258  1.00 43.14  ?  232 LYS   A N    1 
ATOM   8478  C  CA   . LYS   B 1 233 ? 33.830  -22.440 27.527  1.00 39.40  ?  232 LYS   A CA   1 
ATOM   8479  C  C    . LYS   B 1 233 ? 32.828  -21.286 27.510  1.00 42.14  ?  232 LYS   A C    1 
ATOM   8480  O  O    . LYS   B 1 233 ? 33.181  -20.208 27.131  1.00 39.25  ?  232 LYS   A O    1 
ATOM   8481  C  CB   . LYS   B 1 233 ? 34.897  -22.203 28.565  1.00 39.03  ?  232 LYS   A CB   1 
ATOM   8482  C  CG   . LYS   B 1 233 ? 34.493  -22.388 29.989  1.00 41.20  ?  232 LYS   A CG   1 
ATOM   8483  C  CD   . LYS   B 1 233 ? 35.726  -22.539 30.832  1.00 46.94  ?  232 LYS   A CD   1 
ATOM   8484  C  CE   . LYS   B 1 233 ? 35.540  -21.982 32.203  1.00 53.95  ?  232 LYS   A CE   1 
ATOM   8485  N  NZ   . LYS   B 1 233 ? 36.834  -21.854 32.892  1.00 57.01  ?  232 LYS   A NZ   1 
ATOM   8486  H  H    . LYS   B 1 233 ? 35.043  -21.787 26.292  1.00 51.77  ?  232 LYS   A H    1 
ATOM   8487  H  HA   . LYS   B 1 233 ? 33.412  -23.313 27.679  1.00 47.28  ?  232 LYS   A HA   1 
ATOM   8488  H  HB2  . LYS   B 1 233 ? 35.630  -22.813 28.391  1.00 46.84  ?  232 LYS   A HB2  1 
ATOM   8489  H  HB3  . LYS   B 1 233 ? 35.212  -21.304 28.497  1.00 46.84  ?  232 LYS   A HB3  1 
ATOM   8490  H  HG2  . LYS   B 1 233 ? 34.003  -21.610 30.295  1.00 49.44  ?  232 LYS   A HG2  1 
ATOM   8491  H  HG3  . LYS   B 1 233 ? 33.953  -23.188 30.078  1.00 49.44  ?  232 LYS   A HG3  1 
ATOM   8492  H  HD2  . LYS   B 1 233 ? 35.968  -23.476 30.903  1.00 56.33  ?  232 LYS   A HD2  1 
ATOM   8493  H  HD3  . LYS   B 1 233 ? 36.439  -22.026 30.427  1.00 56.33  ?  232 LYS   A HD3  1 
ATOM   8494  H  HE2  . LYS   B 1 233 ? 35.137  -21.101 32.141  1.00 64.74  ?  232 LYS   A HE2  1 
ATOM   8495  H  HE3  . LYS   B 1 233 ? 34.974  -22.577 32.719  1.00 64.74  ?  232 LYS   A HE3  1 
ATOM   8496  H  HZ1  . LYS   B 1 233 ? 36.692  -21.733 33.834  1.00 68.42  ?  232 LYS   A HZ1  1 
ATOM   8497  H  HZ2  . LYS   B 1 233 ? 37.358  -22.647 32.755  1.00 68.42  ?  232 LYS   A HZ2  1 
ATOM   8498  H  HZ3  . LYS   B 1 233 ? 37.315  -21.098 32.548  1.00 68.42  ?  232 LYS   A HZ3  1 
ATOM   8499  N  N    . TYR   B 1 234 ? 31.575  -21.519 27.855  1.00 36.11  ?  233 TYR   A N    1 
ATOM   8500  C  CA   . TYR   B 1 234 ? 30.622  -20.423 27.958  1.00 32.65  ?  233 TYR   A CA   1 
ATOM   8501  C  C    . TYR   B 1 234 ? 29.756  -20.605 29.192  1.00 33.96  ?  233 TYR   A C    1 
ATOM   8502  O  O    . TYR   B 1 234 ? 29.616  -21.706 29.721  1.00 36.69  ?  233 TYR   A O    1 
ATOM   8503  C  CB   . TYR   B 1 234 ? 29.779  -20.277 26.678  1.00 36.47  ?  233 TYR   A CB   1 
ATOM   8504  C  CG   . TYR   B 1 234 ? 28.841  -21.422 26.312  1.00 38.04  ?  233 TYR   A CG   1 
ATOM   8505  C  CD1  . TYR   B 1 234 ? 29.264  -22.445 25.485  1.00 42.07  ?  233 TYR   A CD1  1 
ATOM   8506  C  CD2  . TYR   B 1 234 ? 27.549  -21.463 26.788  1.00 33.85  ?  233 TYR   A CD2  1 
ATOM   8507  C  CE1  . TYR   B 1 234 ? 28.425  -23.488 25.148  1.00 36.09  ?  233 TYR   A CE1  1 
ATOM   8508  C  CE2  . TYR   B 1 234 ? 26.712  -22.501 26.477  1.00 33.63  ?  233 TYR   A CE2  1 
ATOM   8509  C  CZ   . TYR   B 1 234 ? 27.136  -23.504 25.648  1.00 39.59  ?  233 TYR   A CZ   1 
ATOM   8510  O  OH   . TYR   B 1 234 ? 26.287  -24.541 25.330  1.00 43.22  ?  233 TYR   A OH   1 
ATOM   8511  H  H    . TYR   B 1 234 ? 31.287  -22.296 28.084  1.00 43.34  ?  233 TYR   A H    1 
ATOM   8512  H  HA   . TYR   B 1 234 ? 31.106  -19.592 28.083  1.00 39.18  ?  233 TYR   A HA   1 
ATOM   8513  H  HB2  . TYR   B 1 234 ? 29.228  -19.485 26.775  1.00 43.77  ?  233 TYR   A HB2  1 
ATOM   8514  H  HB3  . TYR   B 1 234 ? 30.389  -20.168 25.932  1.00 43.77  ?  233 TYR   A HB3  1 
ATOM   8515  H  HD1  . TYR   B 1 234 ? 30.131  -22.431 25.149  1.00 50.48  ?  233 TYR   A HD1  1 
ATOM   8516  H  HD2  . TYR   B 1 234 ? 27.240  -20.774 27.330  1.00 40.62  ?  233 TYR   A HD2  1 
ATOM   8517  H  HE1  . TYR   B 1 234 ? 28.723  -24.171 24.591  1.00 43.30  ?  233 TYR   A HE1  1 
ATOM   8518  H  HE2  . TYR   B 1 234 ? 25.852  -22.525 26.830  1.00 40.36  ?  233 TYR   A HE2  1 
ATOM   8519  H  HH   . TYR   B 1 234 ? 25.510  -24.369 25.600  1.00 51.86  ?  233 TYR   A HH   1 
ATOM   8520  N  N    . LEU   B 1 235 ? 29.176  -19.493 29.633  1.00 30.41  ?  234 LEU   A N    1 
ATOM   8521  C  CA   . LEU   B 1 235 ? 28.285  -19.450 30.794  1.00 37.24  ?  234 LEU   A CA   1 
ATOM   8522  C  C    . LEU   B 1 235 ? 26.875  -19.932 30.443  1.00 29.84  ?  234 LEU   A C    1 
ATOM   8523  O  O    . LEU   B 1 235 ? 26.199  -19.380 29.564  1.00 30.89  ?  234 LEU   A O    1 
ATOM   8524  C  CB   . LEU   B 1 235 ? 28.234  -18.030 31.349  1.00 32.80  ?  234 LEU   A CB   1 
ATOM   8525  C  CG   . LEU   B 1 235 ? 27.439  -17.787 32.606  1.00 28.12  ?  234 LEU   A CG   1 
ATOM   8526  C  CD1  . LEU   B 1 235 ? 28.046  -18.471 33.813  1.00 30.73  ?  234 LEU   A CD1  1 
ATOM   8527  C  CD2  . LEU   B 1 235 ? 27.406  -16.264 32.775  1.00 30.85  ?  234 LEU   A CD2  1 
ATOM   8528  H  H    . LEU   B 1 235 ? 29.285  -18.723 29.266  1.00 36.49  ?  234 LEU   A H    1 
ATOM   8529  H  HA   . LEU   B 1 235 ? 28.634  -20.055 31.468  1.00 44.69  ?  234 LEU   A HA   1 
ATOM   8530  H  HB2  . LEU   B 1 235 ? 29.144  -17.755 31.538  1.00 39.36  ?  234 LEU   A HB2  1 
ATOM   8531  H  HB3  . LEU   B 1 235 ? 27.850  -17.461 30.663  1.00 39.36  ?  234 LEU   A HB3  1 
ATOM   8532  H  HG   . LEU   B 1 235 ? 26.546  -18.158 32.544  1.00 33.75  ?  234 LEU   A HG   1 
ATOM   8533  H  HD11 . LEU   B 1 235 ? 27.535  -18.230 34.602  1.00 36.88  ?  234 LEU   A HD11 1 
ATOM   8534  H  HD12 . LEU   B 1 235 ? 28.015  -19.431 33.680  1.00 36.88  ?  234 LEU   A HD12 1 
ATOM   8535  H  HD13 . LEU   B 1 235 ? 28.965  -18.179 33.912  1.00 36.88  ?  234 LEU   A HD13 1 
ATOM   8536  H  HD21 . LEU   B 1 235 ? 27.013  -16.050 33.636  1.00 37.02  ?  234 LEU   A HD21 1 
ATOM   8537  H  HD22 . LEU   B 1 235 ? 28.312  -15.921 32.730  1.00 37.02  ?  234 LEU   A HD22 1 
ATOM   8538  H  HD23 . LEU   B 1 235 ? 26.871  -15.879 32.063  1.00 37.02  ?  234 LEU   A HD23 1 
ATOM   8539  N  N    . VAL   B 1 236 ? 26.430  -20.954 31.152  1.00 25.63  ?  235 VAL   A N    1 
ATOM   8540  C  CA   . VAL   B 1 236 ? 25.096  -21.492 30.913  1.00 31.84  ?  235 VAL   A CA   1 
ATOM   8541  C  C    . VAL   B 1 236 ? 24.049  -20.843 31.818  1.00 29.15  ?  235 VAL   A C    1 
ATOM   8542  O  O    . VAL   B 1 236 ? 22.970  -20.513 31.362  1.00 33.07  ?  235 VAL   A O    1 
ATOM   8543  C  CB   . VAL   B 1 236 ? 25.122  -23.011 31.109  1.00 35.39  ?  235 VAL   A CB   1 
ATOM   8544  C  CG1  . VAL   B 1 236 ? 23.720  -23.581 31.167  1.00 31.13  ?  235 VAL   A CG1  1 
ATOM   8545  C  CG2  . VAL   B 1 236 ? 25.900  -23.652 30.003  1.00 36.52  ?  235 VAL   A CG2  1 
ATOM   8546  H  H    . VAL   B 1 236 ? 26.874  -21.352 31.772  1.00 30.76  ?  235 VAL   A H    1 
ATOM   8547  H  HA   . VAL   B 1 236 ? 24.846  -21.298 29.997  1.00 38.21  ?  235 VAL   A HA   1 
ATOM   8548  H  HB   . VAL   B 1 236 ? 25.555  -23.209 31.954  1.00 42.47  ?  235 VAL   A HB   1 
ATOM   8549  H  HG11 . VAL   B 1 236 ? 23.766  -24.545 31.076  1.00 37.35  ?  235 VAL   A HG11 1 
ATOM   8550  H  HG12 . VAL   B 1 236 ? 23.320  -23.348 32.020  1.00 37.35  ?  235 VAL   A HG12 1 
ATOM   8551  H  HG13 . VAL   B 1 236 ? 23.196  -23.204 30.443  1.00 37.35  ?  235 VAL   A HG13 1 
ATOM   8552  H  HG21 . VAL   B 1 236 ? 25.762  -24.612 30.036  1.00 43.82  ?  235 VAL   A HG21 1 
ATOM   8553  H  HG22 . VAL   B 1 236 ? 25.589  -23.302 29.154  1.00 43.82  ?  235 VAL   A HG22 1 
ATOM   8554  H  HG23 . VAL   B 1 236 ? 26.841  -23.449 30.120  1.00 43.82  ?  235 VAL   A HG23 1 
ATOM   8555  N  N    . GLN   B 1 237 ? 24.354  -20.635 33.093  1.00 34.01  ?  236 GLN   A N    1 
ATOM   8556  C  CA   . GLN   B 1 237 ? 23.433  -20.061 34.056  1.00 38.46  ?  236 GLN   A CA   1 
ATOM   8557  C  C    . GLN   B 1 237 ? 24.256  -19.408 35.159  1.00 32.18  ?  236 GLN   A C    1 
ATOM   8558  O  O    . GLN   B 1 237 ? 25.293  -19.946 35.600  1.00 35.79  ?  236 GLN   A O    1 
ATOM   8559  C  CB   . GLN   B 1 237 ? 22.479  -21.125 34.621  1.00 33.89  ?  236 GLN   A CB   1 
ATOM   8560  C  CG   . GLN   B 1 237 ? 21.885  -20.721 35.910  1.00 40.03  ?  236 GLN   A CG   1 
ATOM   8561  C  CD   . GLN   B 1 237 ? 20.383  -20.555 35.811  1.00 49.95  ?  236 GLN   A CD   1 
ATOM   8562  O  OE1  . GLN   B 1 237 ? 19.850  -20.430 34.719  1.00 53.77  ?  236 GLN   A OE1  1 
ATOM   8563  N  NE2  . GLN   B 1 237 ? 19.687  -20.587 36.947  1.00 63.82  ?  236 GLN   A NE2  1 
ATOM   8564  H  H    . GLN   B 1 237 ? 25.119  -20.827 33.436  1.00 40.81  ?  236 GLN   A H    1 
ATOM   8565  H  HA   . GLN   B 1 237 ? 22.885  -19.377 33.641  1.00 46.15  ?  236 GLN   A HA   1 
ATOM   8566  H  HB2  . GLN   B 1 237 ? 21.758  -21.273 33.989  1.00 40.67  ?  236 GLN   A HB2  1 
ATOM   8567  H  HB3  . GLN   B 1 237 ? 22.972  -21.949 34.761  1.00 40.67  ?  236 GLN   A HB3  1 
ATOM   8568  H  HG2  . GLN   B 1 237 ? 22.072  -21.402 36.575  1.00 48.03  ?  236 GLN   A HG2  1 
ATOM   8569  H  HG3  . GLN   B 1 237 ? 22.267  -19.874 36.186  1.00 48.03  ?  236 GLN   A HG3  1 
ATOM   8570  H  HE21 . GLN   B 1 237 ? 20.093  -20.699 37.697  1.00 76.58  ?  236 GLN   A HE21 1 
ATOM   8571  H  HE22 . GLN   B 1 237 ? 18.832  -20.496 36.931  1.00 76.58  ?  236 GLN   A HE22 1 
ATOM   8572  N  N    . GLN   B 1 238 ? 23.757  -18.254 35.613  1.00 31.40  ?  237 GLN   A N    1 
ATOM   8573  C  CA   . GLN   B 1 238 ? 24.371  -17.510 36.699  1.00 35.34  ?  237 GLN   A CA   1 
ATOM   8574  C  C    . GLN   B 1 238 ? 23.312  -17.010 37.669  1.00 32.65  ?  237 GLN   A C    1 
ATOM   8575  O  O    . GLN   B 1 238 ? 22.442  -16.227 37.278  1.00 34.24  ?  237 GLN   A O    1 
ATOM   8576  C  CB   . GLN   B 1 238 ? 25.155  -16.326 36.154  1.00 31.19  ?  237 GLN   A CB   1 
ATOM   8577  C  CG   . GLN   B 1 238 ? 25.822  -15.540 37.275  1.00 33.07  ?  237 GLN   A CG   1 
ATOM   8578  C  CD   . GLN   B 1 238 ? 27.134  -16.186 37.747  1.00 33.02  ?  237 GLN   A CD   1 
ATOM   8579  O  OE1  . GLN   B 1 238 ? 27.774  -16.930 37.014  1.00 31.96  ?  237 GLN   A OE1  1 
ATOM   8580  N  NE2  . GLN   B 1 238 ? 27.525  -15.886 38.970  1.00 29.25  ?  237 GLN   A NE2  1 
ATOM   8581  H  H    . GLN   B 1 238 ? 23.049  -17.880 35.298  1.00 37.68  ?  237 GLN   A H    1 
ATOM   8582  H  HA   . GLN   B 1 238 ? 24.958  -18.109 37.187  1.00 42.41  ?  237 GLN   A HA   1 
ATOM   8583  H  HB2  . GLN   B 1 238 ? 25.846  -16.648 35.553  1.00 37.42  ?  237 GLN   A HB2  1 
ATOM   8584  H  HB3  . GLN   B 1 238 ? 24.553  -15.733 35.679  1.00 37.42  ?  237 GLN   A HB3  1 
ATOM   8585  H  HG2  . GLN   B 1 238 ? 26.023  -14.645 36.959  1.00 39.69  ?  237 GLN   A HG2  1 
ATOM   8586  H  HG3  . GLN   B 1 238 ? 25.218  -15.495 38.034  1.00 39.69  ?  237 GLN   A HG3  1 
ATOM   8587  H  HE21 . GLN   B 1 238 ? 27.053  -15.355 39.454  1.00 35.10  ?  237 GLN   A HE21 1 
ATOM   8588  H  HE22 . GLN   B 1 238 ? 28.253  -16.221 39.283  1.00 35.10  ?  237 GLN   A HE22 1 
ATOM   8589  N  N    . GLU   B 1 239 ? 23.433  -17.384 38.943  1.00 29.76  ?  238 GLU   A N    1 
ATOM   8590  C  CA   . GLU   B 1 239 ? 22.567  -16.847 39.993  1.00 33.29  ?  238 GLU   A CA   1 
ATOM   8591  C  C    . GLU   B 1 239 ? 23.460  -16.283 41.083  1.00 34.07  ?  238 GLU   A C    1 
ATOM   8592  O  O    . GLU   B 1 239 ? 24.182  -17.044 41.741  1.00 32.05  ?  238 GLU   A O    1 
ATOM   8593  C  CB   . GLU   B 1 239 ? 21.637  -17.915 40.558  1.00 39.67  ?  238 GLU   A CB   1 
ATOM   8594  C  CG   . GLU   B 1 239 ? 20.932  -18.745 39.490  1.00 42.51  ?  238 GLU   A CG   1 
ATOM   8595  C  CD   . GLU   B 1 239 ? 19.470  -18.952 39.799  1.00 60.77  ?  238 GLU   A CD   1 
ATOM   8596  O  OE1  . GLU   B 1 239 ? 19.070  -20.105 40.093  1.00 66.46  ?  238 GLU   A OE1  1 
ATOM   8597  O  OE2  . GLU   B 1 239 ? 18.722  -17.951 39.754  1.00 65.71  ?  238 GLU   A OE2  1 
ATOM   8598  H  H    . GLU   B 1 239 ? 24.014  -17.951 39.225  1.00 35.72  ?  238 GLU   A H    1 
ATOM   8599  H  HA   . GLU   B 1 239 ? 22.018  -16.137 39.626  1.00 39.95  ?  238 GLU   A HA   1 
ATOM   8600  H  HB2  . GLU   B 1 239 ? 22.156  -18.522 41.108  1.00 47.60  ?  238 GLU   A HB2  1 
ATOM   8601  H  HB3  . GLU   B 1 239 ? 20.954  -17.482 41.094  1.00 47.60  ?  238 GLU   A HB3  1 
ATOM   8602  H  HG2  . GLU   B 1 239 ? 20.998  -18.288 38.637  1.00 51.01  ?  238 GLU   A HG2  1 
ATOM   8603  H  HG3  . GLU   B 1 239 ? 21.355  -19.616 39.433  1.00 51.01  ?  238 GLU   A HG3  1 
ATOM   8604  N  N    . SER   B 1 240 ? 23.441  -14.945 41.232  1.00 25.40  ?  239 SER   A N    1 
ATOM   8605  C  CA   . SER   B 1 240 ? 24.256  -14.212 42.178  1.00 33.57  ?  239 SER   A CA   1 
ATOM   8606  C  C    . SER   B 1 240 ? 23.952  -12.730 42.021  1.00 31.96  ?  239 SER   A C    1 
ATOM   8607  O  O    . SER   B 1 240 ? 23.618  -12.281 40.915  1.00 28.08  ?  239 SER   A O    1 
ATOM   8608  C  CB   . SER   B 1 240 ? 25.752  -14.455 41.950  1.00 29.77  ?  239 SER   A CB   1 
ATOM   8609  O  OG   . SER   B 1 240 ? 26.129  -13.955 40.657  1.00 30.02  ?  239 SER   A OG   1 
ATOM   8610  H  H    . SER   B 1 240 ? 22.936  -14.427 40.767  1.00 30.47  ?  239 SER   A H    1 
ATOM   8611  H  HA   . SER   B 1 240 ? 24.047  -14.507 43.078  1.00 40.29  ?  239 SER   A HA   1 
ATOM   8612  H  HB2  . SER   B 1 240 ? 26.261  -13.991 42.633  1.00 35.73  ?  239 SER   A HB2  1 
ATOM   8613  H  HB3  . SER   B 1 240 ? 25.933  -15.407 41.990  1.00 35.73  ?  239 SER   A HB3  1 
ATOM   8614  H  HG   . SER   B 1 240 ? 26.966  -13.951 40.584  1.00 36.02  ?  239 SER   A HG   1 
ATOM   8615  N  N    . PRO   B 1 241 ? 24.129  -11.931 43.088  1.00 29.51  ?  240 PRO   A N    1 
ATOM   8616  C  CA   . PRO   B 1 241 ? 23.929  -10.475 42.965  1.00 28.75  ?  240 PRO   A CA   1 
ATOM   8617  C  C    . PRO   B 1 241 ? 25.000  -9.773  42.140  1.00 33.98  ?  240 PRO   A C    1 
ATOM   8618  O  O    . PRO   B 1 241 ? 24.817  -8.607  41.742  1.00 31.84  ?  240 PRO   A O    1 
ATOM   8619  C  CB   . PRO   B 1 241 ? 23.972  -9.990  44.409  1.00 32.70  ?  240 PRO   A CB   1 
ATOM   8620  C  CG   . PRO   B 1 241 ? 24.656  -11.041 45.149  1.00 31.04  ?  240 PRO   A CG   1 
ATOM   8621  C  CD   . PRO   B 1 241 ? 24.681  -12.311 44.393  1.00 32.95  ?  240 PRO   A CD   1 
ATOM   8622  H  HA   . PRO   B 1 241 ? 23.055  -10.300 42.582  1.00 34.50  ?  240 PRO   A HA   1 
ATOM   8623  H  HB2  . PRO   B 1 241 ? 24.463  -9.155  44.461  1.00 39.24  ?  240 PRO   A HB2  1 
ATOM   8624  H  HB3  . PRO   B 1 241 ? 23.069  -9.865  44.741  1.00 39.24  ?  240 PRO   A HB3  1 
ATOM   8625  H  HG2  . PRO   B 1 241 ? 25.565  -10.749 45.320  1.00 37.24  ?  240 PRO   A HG2  1 
ATOM   8626  H  HG3  . PRO   B 1 241 ? 24.187  -11.175 45.988  1.00 37.24  ?  240 PRO   A HG3  1 
ATOM   8627  H  HD2  . PRO   B 1 241 ? 25.588  -12.641 44.302  1.00 39.55  ?  240 PRO   A HD2  1 
ATOM   8628  H  HD3  . PRO   B 1 241 ? 24.126  -12.981 44.822  1.00 39.55  ?  240 PRO   A HD3  1 
ATOM   8629  N  N    . PHE   B 1 242 ? 26.112  -10.442 41.864  1.00 31.03  ?  241 PHE   A N    1 
ATOM   8630  C  CA   . PHE   B 1 242 ? 27.162  -9.790  41.098  1.00 31.24  ?  241 PHE   A CA   1 
ATOM   8631  C  C    . PHE   B 1 242 ? 28.097  -10.853 40.558  1.00 27.17  ?  241 PHE   A C    1 
ATOM   8632  O  O    . PHE   B 1 242 ? 28.117  -11.994 41.018  1.00 26.96  ?  241 PHE   A O    1 
ATOM   8633  C  CB   . PHE   B 1 242 ? 27.948  -8.768  41.947  1.00 26.61  ?  241 PHE   A CB   1 
ATOM   8634  C  CG   . PHE   B 1 242 ? 28.703  -9.400  43.092  1.00 30.08  ?  241 PHE   A CG   1 
ATOM   8635  C  CD1  . PHE   B 1 242 ? 28.110  -9.550  44.338  1.00 35.51  ?  241 PHE   A CD1  1 
ATOM   8636  C  CD2  . PHE   B 1 242 ? 29.988  -9.867  42.919  1.00 36.64  ?  241 PHE   A CD2  1 
ATOM   8637  C  CE1  . PHE   B 1 242 ? 28.780  -10.141 45.365  1.00 36.65  ?  241 PHE   A CE1  1 
ATOM   8638  C  CE2  . PHE   B 1 242 ? 30.648  -10.480 43.954  1.00 39.67  ?  241 PHE   A CE2  1 
ATOM   8639  C  CZ   . PHE   B 1 242 ? 30.038  -10.601 45.176  1.00 42.59  ?  241 PHE   A CZ   1 
ATOM   8640  H  H    . PHE   B 1 242 ? 26.277  -11.251 42.102  1.00 37.23  ?  241 PHE   A H    1 
ATOM   8641  H  HA   . PHE   B 1 242 ? 26.753  -9.320  40.354  1.00 37.48  ?  241 PHE   A HA   1 
ATOM   8642  H  HB2  . PHE   B 1 242 ? 28.591  -8.316  41.379  1.00 31.93  ?  241 PHE   A HB2  1 
ATOM   8643  H  HB3  . PHE   B 1 242 ? 27.325  -8.124  42.320  1.00 31.93  ?  241 PHE   A HB3  1 
ATOM   8644  H  HD1  . PHE   B 1 242 ? 27.243  -9.242  44.473  1.00 42.62  ?  241 PHE   A HD1  1 
ATOM   8645  H  HD2  . PHE   B 1 242 ? 30.411  -9.766  42.096  1.00 43.97  ?  241 PHE   A HD2  1 
ATOM   8646  H  HE1  . PHE   B 1 242 ? 28.372  -10.229 46.197  1.00 43.98  ?  241 PHE   A HE1  1 
ATOM   8647  H  HE2  . PHE   B 1 242 ? 31.507  -10.812 43.827  1.00 47.60  ?  241 PHE   A HE2  1 
ATOM   8648  H  HZ   . PHE   B 1 242 ? 30.493  -11.002 45.881  1.00 51.11  ?  241 PHE   A HZ   1 
ATOM   8649  N  N    . VAL   B 1 243 ? 28.919  -10.439 39.602  1.00 24.90  ?  242 VAL   A N    1 
ATOM   8650  C  CA   . VAL   B 1 243 ? 30.063  -11.240 39.182  1.00 28.46  ?  242 VAL   A CA   1 
ATOM   8651  C  C    . VAL   B 1 243 ? 31.291  -10.356 39.132  1.00 32.31  ?  242 VAL   A C    1 
ATOM   8652  O  O    . VAL   B 1 243 ? 31.196  -9.185  38.767  1.00 33.10  ?  242 VAL   A O    1 
ATOM   8653  C  CB   . VAL   B 1 243 ? 29.820  -11.905 37.815  1.00 23.18  ?  242 VAL   A CB   1 
ATOM   8654  C  CG1  . VAL   B 1 243 ? 28.558  -12.763 37.933  1.00 29.31  ?  242 VAL   A CG1  1 
ATOM   8655  C  CG2  . VAL   B 1 243 ? 29.708  -10.867 36.763  1.00 26.81  ?  242 VAL   A CG2  1 
ATOM   8656  H  H    . VAL   B 1 243 ? 28.835  -9.694  39.180  1.00 29.88  ?  242 VAL   A H    1 
ATOM   8657  H  HA   . VAL   B 1 243 ? 30.216  -11.935 39.841  1.00 34.15  ?  242 VAL   A HA   1 
ATOM   8658  H  HB   . VAL   B 1 243 ? 30.559  -12.477 37.554  1.00 27.81  ?  242 VAL   A HB   1 
ATOM   8659  H  HG11 . VAL   B 1 243 ? 28.258  -13.007 37.044  1.00 35.17  ?  242 VAL   A HG11 1 
ATOM   8660  H  HG12 . VAL   B 1 243 ? 28.766  -13.561 38.443  1.00 35.17  ?  242 VAL   A HG12 1 
ATOM   8661  H  HG13 . VAL   B 1 243 ? 27.870  -12.251 38.386  1.00 35.17  ?  242 VAL   A HG13 1 
ATOM   8662  H  HG21 . VAL   B 1 243 ? 29.361  -11.274 35.954  1.00 32.17  ?  242 VAL   A HG21 1 
ATOM   8663  H  HG22 . VAL   B 1 243 ? 29.104  -10.172 37.069  1.00 32.17  ?  242 VAL   A HG22 1 
ATOM   8664  H  HG23 . VAL   B 1 243 ? 30.586  -10.492 36.594  1.00 32.17  ?  242 VAL   A HG23 1 
ATOM   8665  N  N    . MET   B 1 244 ? 32.439  -10.918 39.478  1.00 24.16  ?  243 MET   A N    1 
ATOM   8666  C  CA   . MET   B 1 244 ? 33.744  -10.281 39.303  1.00 32.08  ?  243 MET   A CA   1 
ATOM   8667  C  C    . MET   B 1 244 ? 34.527  -11.000 38.203  1.00 29.79  ?  243 MET   A C    1 
ATOM   8668  O  O    . MET   B 1 244 ? 34.889  -12.177 38.366  1.00 27.08  ?  243 MET   A O    1 
ATOM   8669  C  CB   . MET   B 1 244 ? 34.505  -10.329 40.623  1.00 26.62  ?  243 MET   A CB   1 
ATOM   8670  C  CG   . MET   B 1 244 ? 35.763  -9.539  40.667  1.00 30.74  ?  243 MET   A CG   1 
ATOM   8671  S  SD   . MET   B 1 244 ? 36.801  -9.938  42.141  1.00 37.71  ?  243 MET   A SD   1 
ATOM   8672  C  CE   . MET   B 1 244 ? 38.252  -9.077  41.590  1.00 46.75  ?  243 MET   A CE   1 
ATOM   8673  H  H    . MET   B 1 244 ? 32.494  -11.701 39.830  1.00 28.99  ?  243 MET   A H    1 
ATOM   8674  H  HA   . MET   B 1 244 ? 33.614  -9.360  39.026  1.00 38.50  ?  243 MET   A HA   1 
ATOM   8675  H  HB2  . MET   B 1 244 ? 33.925  -9.987  41.321  1.00 31.95  ?  243 MET   A HB2  1 
ATOM   8676  H  HB3  . MET   B 1 244 ? 34.737  -11.252 40.807  1.00 31.95  ?  243 MET   A HB3  1 
ATOM   8677  H  HG2  . MET   B 1 244 ? 36.284  -9.730  39.872  1.00 36.89  ?  243 MET   A HG2  1 
ATOM   8678  H  HG3  . MET   B 1 244 ? 35.543  -8.595  40.701  1.00 36.89  ?  243 MET   A HG3  1 
ATOM   8679  H  HE1  . MET   B 1 244 ? 38.919  -9.100  42.294  1.00 56.10  ?  243 MET   A HE1  1 
ATOM   8680  H  HE2  . MET   B 1 244 ? 38.595  -9.513  40.795  1.00 56.10  ?  243 MET   A HE2  1 
ATOM   8681  H  HE3  . MET   B 1 244 ? 38.016  -8.158  41.388  1.00 56.10  ?  243 MET   A HE3  1 
ATOM   8682  N  N    . MET   B 1 245 ? 34.798  -10.277 37.104  1.00 28.27  ?  244 MET   A N    1 
ATOM   8683  C  CA   . MET   B 1 245 ? 35.601  -10.768 35.981  1.00 27.17  ?  244 MET   A CA   1 
ATOM   8684  C  C    . MET   B 1 245 ? 36.985  -10.133 36.073  1.00 29.94  ?  244 MET   A C    1 
ATOM   8685  O  O    . MET   B 1 245 ? 37.111  -8.903  36.081  1.00 29.13  ?  244 MET   A O    1 
ATOM   8686  C  CB   . MET   B 1 245 ? 35.019  -10.379 34.626  1.00 26.76  ?  244 MET   A CB   1 
ATOM   8687  C  CG   . MET   B 1 245 ? 33.570  -10.726 34.387  1.00 28.97  ?  244 MET   A CG   1 
ATOM   8688  S  SD   . MET   B 1 245 ? 33.323  -12.497 34.477  1.00 29.85  ?  244 MET   A SD   1 
ATOM   8689  C  CE   . MET   B 1 245 ? 34.174  -13.068 33.024  1.00 29.39  ?  244 MET   A CE   1 
ATOM   8690  H  H    . MET   B 1 245 ? 34.518  -9.473  36.987  1.00 33.93  ?  244 MET   A H    1 
ATOM   8691  H  HA   . MET   B 1 245 ? 35.627  -11.736 36.035  1.00 32.60  ?  244 MET   A HA   1 
ATOM   8692  H  HB2  . MET   B 1 245 ? 35.100  -9.417  34.529  1.00 32.11  ?  244 MET   A HB2  1 
ATOM   8693  H  HB3  . MET   B 1 245 ? 35.536  -10.826 33.937  1.00 32.11  ?  244 MET   A HB3  1 
ATOM   8694  H  HG2  . MET   B 1 245 ? 33.019  -10.302 35.064  1.00 34.77  ?  244 MET   A HG2  1 
ATOM   8695  H  HG3  . MET   B 1 245 ? 33.305  -10.422 33.505  1.00 34.77  ?  244 MET   A HG3  1 
ATOM   8696  H  HE1  . MET   B 1 245 ? 34.118  -14.036 32.985  1.00 35.27  ?  244 MET   A HE1  1 
ATOM   8697  H  HE2  . MET   B 1 245 ? 33.754  -12.681 32.240  1.00 35.27  ?  244 MET   A HE2  1 
ATOM   8698  H  HE3  . MET   B 1 245 ? 35.102  -12.792 33.073  1.00 35.27  ?  244 MET   A HE3  1 
ATOM   8699  N  N    . SER   B 1 246 ? 38.022  -10.938 36.082  1.00 25.59  ?  245 SER   A N    1 
ATOM   8700  C  CA   . SER   B 1 246 ? 39.356  -10.393 36.278  1.00 30.62  ?  245 SER   A CA   1 
ATOM   8701  C  C    . SER   B 1 246 ? 40.339  -10.967 35.265  1.00 27.43  ?  245 SER   A C    1 
ATOM   8702  O  O    . SER   B 1 246 ? 40.102  -12.036 34.691  1.00 26.56  ?  245 SER   A O    1 
ATOM   8703  C  CB   . SER   B 1 246 ? 39.736  -10.651 37.733  1.00 31.15  ?  245 SER   A CB   1 
ATOM   8704  O  OG   . SER   B 1 246 ? 41.105  -10.362 37.914  1.00 51.07  ?  245 SER   A OG   1 
ATOM   8705  H  H    . SER   B 1 246 ? 37.985  -11.791 35.979  1.00 30.71  ?  245 SER   A H    1 
ATOM   8706  H  HA   . SER   B 1 246 ? 39.408  -9.440  36.103  1.00 36.74  ?  245 SER   A HA   1 
ATOM   8707  H  HB2  . SER   B 1 246 ? 39.206  -10.079 38.310  1.00 37.38  ?  245 SER   A HB2  1 
ATOM   8708  H  HB3  . SER   B 1 246 ? 39.572  -11.583 37.948  1.00 37.38  ?  245 SER   A HB3  1 
ATOM   8709  H  HG   . SER   B 1 246 ? 41.202  -9.820  38.548  1.00 61.28  ?  245 SER   A HG   1 
ATOM   8710  N  N    . ALA   B 1 247 ? 41.398  -10.202 34.979  1.00 31.95  ?  246 ALA   A N    1 
ATOM   8711  C  CA   . ALA   B 1 247 ? 42.485  -10.681 34.119  1.00 27.76  ?  246 ALA   A CA   1 
ATOM   8712  C  C    . ALA   B 1 247 ? 43.757  -9.880  34.404  1.00 27.39  ?  246 ALA   A C    1 
ATOM   8713  O  O    . ALA   B 1 247 ? 43.708  -8.741  34.911  1.00 23.97  ?  246 ALA   A O    1 
ATOM   8714  C  CB   . ALA   B 1 247 ? 42.110  -10.593 32.621  1.00 27.60  ?  246 ALA   A CB   1 
ATOM   8715  H  H    . ALA   B 1 247 ? 41.510  -9.401  35.271  1.00 38.34  ?  246 ALA   A H    1 
ATOM   8716  H  HA   . ALA   B 1 247 ? 42.666  -11.608 34.338  1.00 33.32  ?  246 ALA   A HA   1 
ATOM   8717  H  HB1  . ALA   B 1 247 ? 42.895  -10.792 32.086  1.00 33.12  ?  246 ALA   A HB1  1 
ATOM   8718  H  HB2  . ALA   B 1 247 ? 41.409  -11.237 32.432  1.00 33.12  ?  246 ALA   A HB2  1 
ATOM   8719  H  HB3  . ALA   B 1 247 ? 41.796  -9.696  32.426  1.00 33.12  ?  246 ALA   A HB3  1 
ATOM   8720  N  N    . PRO   B 1 248 ? 44.919  -10.426 34.059  1.00 28.31  ?  247 PRO   A N    1 
ATOM   8721  C  CA   . PRO   B 1 248 ? 46.113  -9.625  34.130  1.00 24.08  ?  247 PRO   A CA   1 
ATOM   8722  C  C    . PRO   B 1 248 ? 45.874  -8.317  33.401  1.00 27.86  ?  247 PRO   A C    1 
ATOM   8723  O  O    . PRO   B 1 248 ? 45.110  -8.290  32.421  1.00 32.84  ?  247 PRO   A O    1 
ATOM   8724  C  CB   . PRO   B 1 248 ? 47.182  -10.501 33.441  1.00 30.75  ?  247 PRO   A CB   1 
ATOM   8725  C  CG   . PRO   B 1 248 ? 46.707  -11.915 33.619  1.00 23.93  ?  247 PRO   A CG   1 
ATOM   8726  C  CD   . PRO   B 1 248 ? 45.183  -11.742 33.440  1.00 31.33  ?  247 PRO   A CD   1 
ATOM   8727  H  HA   . PRO   B 1 248 ? 46.398  -9.458  35.043  1.00 28.90  ?  247 PRO   A HA   1 
ATOM   8728  H  HB2  . PRO   B 1 248 ? 47.239  -10.271 32.500  1.00 36.90  ?  247 PRO   A HB2  1 
ATOM   8729  H  HB3  . PRO   B 1 248 ? 48.042  -10.368 33.868  1.00 36.90  ?  247 PRO   A HB3  1 
ATOM   8730  H  HG2  . PRO   B 1 248 ? 47.087  -12.496 32.940  1.00 28.71  ?  247 PRO   A HG2  1 
ATOM   8731  H  HG3  . PRO   B 1 248 ? 46.932  -12.247 34.502  1.00 28.71  ?  247 PRO   A HG3  1 
ATOM   8732  H  HD2  . PRO   B 1 248 ? 44.943  -11.737 32.500  1.00 37.59  ?  247 PRO   A HD2  1 
ATOM   8733  H  HD3  . PRO   B 1 248 ? 44.699  -12.445 33.901  1.00 37.59  ?  247 PRO   A HD3  1 
ATOM   8734  N  N    . PRO   B 1 249 ? 46.472  -7.216  33.861  1.00 29.74  ?  248 PRO   A N    1 
ATOM   8735  C  CA   . PRO   B 1 249 ? 46.123  -5.907  33.303  1.00 31.30  ?  248 PRO   A CA   1 
ATOM   8736  C  C    . PRO   B 1 249 ? 46.498  -5.788  31.839  1.00 33.11  ?  248 PRO   A C    1 
ATOM   8737  O  O    . PRO   B 1 249 ? 47.519  -6.310  31.402  1.00 26.91  ?  248 PRO   A O    1 
ATOM   8738  C  CB   . PRO   B 1 249 ? 46.907  -4.918  34.173  1.00 27.60  ?  248 PRO   A CB   1 
ATOM   8739  C  CG   . PRO   B 1 249 ? 47.688  -5.681  35.103  1.00 31.18  ?  248 PRO   A CG   1 
ATOM   8740  C  CD   . PRO   B 1 249 ? 47.314  -7.111  35.066  1.00 28.88  ?  248 PRO   A CD   1 
ATOM   8741  H  HA   . PRO   B 1 249 ? 45.171  -5.747  33.402  1.00 37.56  ?  248 PRO   A HA   1 
ATOM   8742  H  HB2  . PRO   B 1 249 ? 47.484  -4.383  33.606  1.00 33.12  ?  248 PRO   A HB2  1 
ATOM   8743  H  HB3  . PRO   B 1 249 ? 46.283  -4.345  34.646  1.00 33.12  ?  248 PRO   A HB3  1 
ATOM   8744  H  HG2  . PRO   B 1 249 ? 48.624  -5.585  34.866  1.00 37.42  ?  248 PRO   A HG2  1 
ATOM   8745  H  HG3  . PRO   B 1 249 ? 47.532  -5.328  35.993  1.00 37.42  ?  248 PRO   A HG3  1 
ATOM   8746  H  HD2  . PRO   B 1 249 ? 48.102  -7.671  34.985  1.00 34.66  ?  248 PRO   A HD2  1 
ATOM   8747  H  HD3  . PRO   B 1 249 ? 46.813  -7.356  35.860  1.00 34.66  ?  248 PRO   A HD3  1 
ATOM   8748  N  N    . ALA   B 1 250 ? 45.620  -5.111  31.095  1.00 34.21  ?  249 ALA   A N    1 
ATOM   8749  C  CA   . ALA   B 1 250 ? 45.723  -4.869  29.664  1.00 31.27  ?  249 ALA   A CA   1 
ATOM   8750  C  C    . ALA   B 1 250 ? 44.849  -3.664  29.336  1.00 27.63  ?  249 ALA   A C    1 
ATOM   8751  O  O    . ALA   B 1 250 ? 43.810  -3.456  29.954  1.00 33.68  ?  249 ALA   A O    1 
ATOM   8752  C  CB   . ALA   B 1 250 ? 45.270  -6.088  28.854  1.00 27.21  ?  249 ALA   A CB   1 
ATOM   8753  H  H    . ALA   B 1 250 ? 44.908  -4.758  31.423  1.00 41.05  ?  249 ALA   A H    1 
ATOM   8754  H  HA   . ALA   B 1 250 ? 46.642  -4.673  29.424  1.00 37.52  ?  249 ALA   A HA   1 
ATOM   8755  H  HB1  . ALA   B 1 250 ? 45.319  -5.875  27.909  1.00 32.65  ?  249 ALA   A HB1  1 
ATOM   8756  H  HB2  . ALA   B 1 250 ? 45.855  -6.836  29.056  1.00 32.65  ?  249 ALA   A HB2  1 
ATOM   8757  H  HB3  . ALA   B 1 250 ? 44.357  -6.308  29.097  1.00 32.65  ?  249 ALA   A HB3  1 
ATOM   8758  N  N    . GLN   B 1 251 ? 45.272  -2.888  28.347  1.00 34.68  ?  250 GLN   A N    1 
ATOM   8759  C  CA   . GLN   B 1 251 ? 44.424  -1.827  27.818  1.00 36.55  ?  250 GLN   A CA   1 
ATOM   8760  C  C    . GLN   B 1 251 ? 43.044  -2.364  27.496  1.00 30.39  ?  250 GLN   A C    1 
ATOM   8761  O  O    . GLN   B 1 251 ? 42.896  -3.440  26.923  1.00 33.71  ?  250 GLN   A O    1 
ATOM   8762  C  CB   . GLN   B 1 251 ? 45.012  -1.190  26.545  1.00 36.14  ?  250 GLN   A CB   1 
ATOM   8763  C  CG   . GLN   B 1 251 ? 46.003  -0.083  26.848  1.00 42.45  ?  250 GLN   A CG   1 
ATOM   8764  C  CD   . GLN   B 1 251 ? 45.359  1.107   27.517  1.00 40.30  ?  250 GLN   A CD   1 
ATOM   8765  O  OE1  . GLN   B 1 251 ? 45.188  1.120   28.721  1.00 39.49  ?  250 GLN   A OE1  1 
ATOM   8766  N  NE2  . GLN   B 1 251 ? 44.995  2.113   26.737  1.00 33.43  ?  250 GLN   A NE2  1 
ATOM   8767  H  H    . GLN   B 1 251 ? 46.040  -2.955  27.965  1.00 41.61  ?  250 GLN   A H    1 
ATOM   8768  H  HA   . GLN   B 1 251 ? 44.367  -1.135  28.496  1.00 43.86  ?  250 GLN   A HA   1 
ATOM   8769  H  HB2  . GLN   B 1 251 ? 45.472  -1.874  26.033  1.00 43.37  ?  250 GLN   A HB2  1 
ATOM   8770  H  HB3  . GLN   B 1 251 ? 44.290  -0.812  26.019  1.00 43.37  ?  250 GLN   A HB3  1 
ATOM   8771  H  HG2  . GLN   B 1 251 ? 46.689  -0.427  27.441  1.00 50.93  ?  250 GLN   A HG2  1 
ATOM   8772  H  HG3  . GLN   B 1 251 ? 46.403  0.219   26.018  1.00 50.93  ?  250 GLN   A HG3  1 
ATOM   8773  H  HE21 . GLN   B 1 251 ? 45.129  2.069   25.888  1.00 40.12  ?  250 GLN   A HE21 1 
ATOM   8774  H  HE22 . GLN   B 1 251 ? 44.624  2.810   27.079  1.00 40.12  ?  250 GLN   A HE22 1 
ATOM   8775  N  N    . TYR   B 1 252 ? 42.034  -1.568  27.814  1.00 35.69  ?  251 TYR   A N    1 
ATOM   8776  C  CA   . TYR   B 1 252 ? 40.653  -2.017  27.787  1.00 30.56  ?  251 TYR   A CA   1 
ATOM   8777  C  C    . TYR   B 1 252 ? 39.750  -0.792  27.680  1.00 33.08  ?  251 TYR   A C    1 
ATOM   8778  O  O    . TYR   B 1 252 ? 39.995  0.233   28.317  1.00 30.68  ?  251 TYR   A O    1 
ATOM   8779  C  CB   . TYR   B 1 252 ? 40.354  -2.857  29.045  1.00 30.25  ?  251 TYR   A CB   1 
ATOM   8780  C  CG   . TYR   B 1 252 ? 39.100  -3.704  28.961  1.00 33.87  ?  251 TYR   A CG   1 
ATOM   8781  C  CD1  . TYR   B 1 252 ? 37.869  -3.204  29.422  1.00 41.12  ?  251 TYR   A CD1  1 
ATOM   8782  C  CD2  . TYR   B 1 252 ? 39.137  -4.986  28.431  1.00 29.81  ?  251 TYR   A CD2  1 
ATOM   8783  C  CE1  . TYR   B 1 252 ? 36.728  -3.940  29.326  1.00 40.05  ?  251 TYR   A CE1  1 
ATOM   8784  C  CE2  . TYR   B 1 252 ? 38.008  -5.747  28.344  1.00 32.59  ?  251 TYR   A CE2  1 
ATOM   8785  C  CZ   . TYR   B 1 252 ? 36.781  -5.218  28.777  1.00 38.82  ?  251 TYR   A CZ   1 
ATOM   8786  O  OH   . TYR   B 1 252 ? 35.634  -6.000  28.707  1.00 38.48  ?  251 TYR   A OH   1 
ATOM   8787  H  H    . TYR   B 1 252 ? 42.124  -0.746  28.052  1.00 42.83  ?  251 TYR   A H    1 
ATOM   8788  H  HA   . TYR   B 1 252 ? 40.472  -2.569  27.010  1.00 36.68  ?  251 TYR   A HA   1 
ATOM   8789  H  HB2  . TYR   B 1 252 ? 41.100  -3.457  29.199  1.00 36.31  ?  251 TYR   A HB2  1 
ATOM   8790  H  HB3  . TYR   B 1 252 ? 40.249  -2.256  29.799  1.00 36.31  ?  251 TYR   A HB3  1 
ATOM   8791  H  HD1  . TYR   B 1 252 ? 37.833  -2.355  29.800  1.00 49.34  ?  251 TYR   A HD1  1 
ATOM   8792  H  HD2  . TYR   B 1 252 ? 39.946  -5.333  28.129  1.00 35.77  ?  251 TYR   A HD2  1 
ATOM   8793  H  HE1  . TYR   B 1 252 ? 35.919  -3.591  29.624  1.00 48.06  ?  251 TYR   A HE1  1 
ATOM   8794  H  HE2  . TYR   B 1 252 ? 38.051  -6.611  28.002  1.00 39.11  ?  251 TYR   A HE2  1 
ATOM   8795  H  HH   . TYR   B 1 252 ? 35.632  -6.444  27.994  1.00 46.17  ?  251 TYR   A HH   1 
ATOM   8796  N  N    . GLU   B 1 253 ? 38.687  -0.918  26.889  1.00 39.36  ?  252 GLU   A N    1 
ATOM   8797  C  CA   . GLU   B 1 253 ? 37.716  0.152   26.733  1.00 41.52  ?  252 GLU   A CA   1 
ATOM   8798  C  C    . GLU   B 1 253 ? 36.517  -0.139  27.635  1.00 42.44  ?  252 GLU   A C    1 
ATOM   8799  O  O    . GLU   B 1 253 ? 35.998  -1.260  27.645  1.00 41.98  ?  252 GLU   A O    1 
ATOM   8800  C  CB   . GLU   B 1 253 ? 37.327  0.256   25.272  1.00 50.65  ?  252 GLU   A CB   1 
ATOM   8801  C  CG   . GLU   B 1 253 ? 36.451  1.389   24.896  1.00 58.58  ?  252 GLU   A CG   1 
ATOM   8802  C  CD   . GLU   B 1 253 ? 35.772  1.058   23.592  1.00 70.24  ?  252 GLU   A CD   1 
ATOM   8803  O  OE1  . GLU   B 1 253 ? 36.376  1.324   22.528  1.00 67.47  ?  252 GLU   A OE1  1 
ATOM   8804  O  OE2  . GLU   B 1 253 ? 34.661  0.474   23.645  1.00 81.48  ?  252 GLU   A OE2  1 
ATOM   8805  H  H    . GLU   B 1 253 ? 38.509  -1.622  26.428  1.00 47.23  ?  252 GLU   A H    1 
ATOM   8806  H  HA   . GLU   B 1 253 ? 38.072  1.011   27.008  1.00 49.83  ?  252 GLU   A HA   1 
ATOM   8807  H  HB2  . GLU   B 1 253 ? 38.141  0.341   24.751  1.00 60.78  ?  252 GLU   A HB2  1 
ATOM   8808  H  HB3  . GLU   B 1 253 ? 36.860  -0.558  25.027  1.00 60.78  ?  252 GLU   A HB3  1 
ATOM   8809  H  HG2  . GLU   B 1 253 ? 35.776  1.527   25.579  1.00 70.29  ?  252 GLU   A HG2  1 
ATOM   8810  H  HG3  . GLU   B 1 253 ? 36.979  2.194   24.784  1.00 70.29  ?  252 GLU   A HG3  1 
ATOM   8811  N  N    . LEU   B 1 254 ? 36.106  0.851   28.426  1.00 41.00  ?  253 LEU   A N    1 
ATOM   8812  C  CA   . LEU   B 1 254 ? 34.951  0.699   29.316  1.00 41.18  ?  253 LEU   A CA   1 
ATOM   8813  C  C    . LEU   B 1 254 ? 33.859  1.663   28.890  1.00 38.79  ?  253 LEU   A C    1 
ATOM   8814  O  O    . LEU   B 1 254 ? 34.087  2.876   28.834  1.00 38.47  ?  253 LEU   A O    1 
ATOM   8815  C  CB   . LEU   B 1 254 ? 35.275  0.965   30.783  1.00 31.33  ?  253 LEU   A CB   1 
ATOM   8816  C  CG   . LEU   B 1 254 ? 36.195  -0.043  31.485  1.00 39.43  ?  253 LEU   A CG   1 
ATOM   8817  C  CD1  . LEU   B 1 254 ? 36.801  0.667   32.685  1.00 38.88  ?  253 LEU   A CD1  1 
ATOM   8818  C  CD2  . LEU   B 1 254 ? 35.574  -1.338  31.957  1.00 33.84  ?  253 LEU   A CD2  1 
ATOM   8819  H  H    . LEU   B 1 254 ? 36.481  1.625   28.465  1.00 49.20  ?  253 LEU   A H    1 
ATOM   8820  H  HA   . LEU   B 1 254 ? 34.650  -0.218  29.227  1.00 49.42  ?  253 LEU   A HA   1 
ATOM   8821  H  HB2  . LEU   B 1 254 ? 35.707  1.831   30.842  1.00 37.60  ?  253 LEU   A HB2  1 
ATOM   8822  H  HB3  . LEU   B 1 254 ? 34.439  0.976   31.276  1.00 37.60  ?  253 LEU   A HB3  1 
ATOM   8823  H  HG   . LEU   B 1 254 ? 36.840  -0.329  30.818  1.00 47.32  ?  253 LEU   A HG   1 
ATOM   8824  H  HD11 . LEU   B 1 254 ? 37.317  0.029   33.202  1.00 46.66  ?  253 LEU   A HD11 1 
ATOM   8825  H  HD12 . LEU   B 1 254 ? 37.377  1.382   32.372  1.00 46.66  ?  253 LEU   A HD12 1 
ATOM   8826  H  HD13 . LEU   B 1 254 ? 36.086  1.032   33.230  1.00 46.66  ?  253 LEU   A HD13 1 
ATOM   8827  H  HD21 . LEU   B 1 254 ? 36.252  -1.871  32.399  1.00 40.61  ?  253 LEU   A HD21 1 
ATOM   8828  H  HD22 . LEU   B 1 254 ? 34.855  -1.136  32.577  1.00 40.61  ?  253 LEU   A HD22 1 
ATOM   8829  H  HD23 . LEU   B 1 254 ? 35.223  -1.818  31.190  1.00 40.61  ?  253 LEU   A HD23 1 
ATOM   8830  N  N    . LYS   B 1 255 ? 32.676  1.128   28.628  1.00 34.27  ?  254 LYS   A N    1 
ATOM   8831  C  CA   . LYS   B 1 255 ? 31.552  1.912   28.137  1.00 40.67  ?  254 LYS   A CA   1 
ATOM   8832  C  C    . LYS   B 1 255 ? 30.534  2.165   29.245  1.00 37.41  ?  254 LYS   A C    1 
ATOM   8833  O  O    . LYS   B 1 255 ? 30.125  1.238   29.956  1.00 32.91  ?  254 LYS   A O    1 
ATOM   8834  C  CB   . LYS   B 1 255 ? 30.881  1.183   26.969  1.00 47.09  ?  254 LYS   A CB   1 
ATOM   8835  C  CG   . LYS   B 1 255 ? 31.721  1.125   25.689  1.00 51.49  ?  254 LYS   A CG   1 
ATOM   8836  C  CD   . LYS   B 1 255 ? 31.579  2.421   24.909  1.00 55.16  ?  254 LYS   A CD   1 
ATOM   8837  C  CE   . LYS   B 1 255 ? 32.575  2.503   23.753  1.00 65.14  ?  254 LYS   A CE   1 
ATOM   8838  N  NZ   . LYS   B 1 255 ? 32.712  3.923   23.268  1.00 66.27  ?  254 LYS   A NZ   1 
ATOM   8839  H  H    . LYS   B 1 255 ? 32.495  0.293   28.729  1.00 41.13  ?  254 LYS   A H    1 
ATOM   8840  H  HA   . LYS   B 1 255 ? 31.874  2.777   27.840  1.00 48.81  ?  254 LYS   A HA   1 
ATOM   8841  H  HB2  . LYS   B 1 255 ? 30.696  0.271   27.239  1.00 56.51  ?  254 LYS   A HB2  1 
ATOM   8842  H  HB3  . LYS   B 1 255 ? 30.053  1.640   26.755  1.00 56.51  ?  254 LYS   A HB3  1 
ATOM   8843  H  HG2  . LYS   B 1 255 ? 32.655  1.000   25.917  1.00 61.79  ?  254 LYS   A HG2  1 
ATOM   8844  H  HG3  . LYS   B 1 255 ? 31.415  0.392   25.131  1.00 61.79  ?  254 LYS   A HG3  1 
ATOM   8845  H  HD2  . LYS   B 1 255 ? 30.683  2.477   24.542  1.00 66.19  ?  254 LYS   A HD2  1 
ATOM   8846  H  HD3  . LYS   B 1 255 ? 31.742  3.170   25.503  1.00 66.19  ?  254 LYS   A HD3  1 
ATOM   8847  H  HE2  . LYS   B 1 255 ? 33.445  2.194   24.051  1.00 78.17  ?  254 LYS   A HE2  1 
ATOM   8848  H  HE3  . LYS   B 1 255 ? 32.263  1.955   23.016  1.00 78.17  ?  254 LYS   A HE3  1 
ATOM   8849  H  HZ1  . LYS   B 1 255 ? 33.153  3.939   22.495  1.00 79.52  ?  254 LYS   A HZ1  1 
ATOM   8850  H  HZ2  . LYS   B 1 255 ? 31.906  4.282   23.148  1.00 79.52  ?  254 LYS   A HZ2  1 
ATOM   8851  H  HZ3  . LYS   B 1 255 ? 33.158  4.407   23.866  1.00 79.52  ?  254 LYS   A HZ3  1 
ATOM   8852  N  N    . HIS   B 1 256 ? 30.127  3.420   29.370  1.00 37.40  ?  255 HIS   A N    1 
ATOM   8853  C  CA   . HIS   B 1 256 ? 29.050  3.805   30.263  1.00 31.43  ?  255 HIS   A CA   1 
ATOM   8854  C  C    . HIS   B 1 256 ? 27.849  2.892   30.100  1.00 34.46  ?  255 HIS   A C    1 
ATOM   8855  O  O    . HIS   B 1 256 ? 27.383  2.646   28.987  1.00 33.82  ?  255 HIS   A O    1 
ATOM   8856  C  CB   . HIS   B 1 256 ? 28.654  5.256   29.972  1.00 27.84  ?  255 HIS   A CB   1 
ATOM   8857  C  CG   . HIS   B 1 256 ? 27.454  5.723   30.734  1.00 39.70  ?  255 HIS   A CG   1 
ATOM   8858  N  ND1  . HIS   B 1 256 ? 26.426  6.406   30.126  1.00 43.92  ?  255 HIS   A ND1  1 
ATOM   8859  C  CD2  . HIS   B 1 256 ? 27.106  5.598   32.038  1.00 42.09  ?  255 HIS   A CD2  1 
ATOM   8860  C  CE1  . HIS   B 1 256 ? 25.490  6.681   31.017  1.00 47.60  ?  255 HIS   A CE1  1 
ATOM   8861  N  NE2  . HIS   B 1 256 ? 25.876  6.199   32.185  1.00 45.82  ?  255 HIS   A NE2  1 
ATOM   8862  H  H    . HIS   B 1 256 ? 30.467  4.082   28.938  1.00 44.89  ?  255 HIS   A H    1 
ATOM   8863  H  HA   . HIS   B 1 256 ? 29.351  3.736   31.182  1.00 37.72  ?  255 HIS   A HA   1 
ATOM   8864  H  HB2  . HIS   B 1 256 ? 29.396  5.835   30.208  1.00 33.41  ?  255 HIS   A HB2  1 
ATOM   8865  H  HB3  . HIS   B 1 256 ? 28.454  5.341   29.027  1.00 33.41  ?  255 HIS   A HB3  1 
ATOM   8866  H  HD2  . HIS   B 1 256 ? 27.604  5.186   32.706  1.00 50.51  ?  255 HIS   A HD2  1 
ATOM   8867  H  HE1  . HIS   B 1 256 ? 24.696  7.136   30.851  1.00 57.12  ?  255 HIS   A HE1  1 
ATOM   8868  H  HE2  . HIS   B 1 256 ? 25.430  6.251   32.919  1.00 54.99  ?  255 HIS   A HE2  1 
ATOM   8869  N  N    . GLY   B 1 257 ? 27.344  2.399   31.216  1.00 32.15  ?  256 GLY   A N    1 
ATOM   8870  C  CA   . GLY   B 1 257 ? 26.150  1.606   31.227  1.00 36.07  ?  256 GLY   A CA   1 
ATOM   8871  C  C    . GLY   B 1 257 ? 26.378  0.114   31.218  1.00 39.31  ?  256 GLY   A C    1 
ATOM   8872  O  O    . GLY   B 1 257 ? 25.465  -0.638  31.588  1.00 41.94  ?  256 GLY   A O    1 
ATOM   8873  H  H    . GLY   B 1 257 ? 27.689  2.518   31.994  1.00 38.58  ?  256 GLY   A H    1 
ATOM   8874  H  HA2  . GLY   B 1 257 ? 25.641  1.822   32.024  1.00 43.29  ?  256 GLY   A HA2  1 
ATOM   8875  H  HA3  . GLY   B 1 257 ? 25.621  1.829   30.445  1.00 43.29  ?  256 GLY   A HA3  1 
ATOM   8876  N  N    . THR   B 1 258 ? 27.559  -0.341  30.819  1.00 28.36  ?  257 THR   A N    1 
ATOM   8877  C  CA   . THR   B 1 258 ? 27.768  -1.765  30.564  1.00 32.51  ?  257 THR   A CA   1 
ATOM   8878  C  C    . THR   B 1 258 ? 28.476  -2.493  31.701  1.00 31.82  ?  257 THR   A C    1 
ATOM   8879  O  O    . THR   B 1 258 ? 28.727  -3.697  31.583  1.00 28.98  ?  257 THR   A O    1 
ATOM   8880  C  CB   . THR   B 1 258 ? 28.587  -1.925  29.297  1.00 34.19  ?  257 THR   A CB   1 
ATOM   8881  O  OG1  . THR   B 1 258 ? 29.873  -1.339  29.567  1.00 40.20  ?  257 THR   A OG1  1 
ATOM   8882  C  CG2  . THR   B 1 258 ? 27.913  -1.170  28.143  1.00 39.29  ?  257 THR   A CG2  1 
ATOM   8883  H  H    . THR   B 1 258 ? 28.252  0.151   30.688  1.00 34.03  ?  257 THR   A H    1 
ATOM   8884  H  HA   . THR   B 1 258 ? 26.902  -2.185  30.445  1.00 39.01  ?  257 THR   A HA   1 
ATOM   8885  H  HB   . THR   B 1 258 ? 28.672  -2.854  29.033  1.00 41.03  ?  257 THR   A HB   1 
ATOM   8886  H  HG1  . THR   B 1 258 ? 30.406  -1.516  28.942  1.00 48.24  ?  257 THR   A HG1  1 
ATOM   8887  H  HG21 . THR   B 1 258 ? 28.235  -1.507  27.293  1.00 47.15  ?  257 THR   A HG21 1 
ATOM   8888  H  HG22 . THR   B 1 258 ? 26.952  -1.289  28.186  1.00 47.15  ?  257 THR   A HG22 1 
ATOM   8889  H  HG23 . THR   B 1 258 ? 28.116  -0.223  28.203  1.00 47.15  ?  257 THR   A HG23 1 
ATOM   8890  N  N    . PHE   B 1 259 ? 28.802  -1.809  32.792  1.00 26.81  ?  258 PHE   A N    1 
ATOM   8891  C  CA   . PHE   B 1 259 ? 29.494  -2.421  33.920  1.00 29.60  ?  258 PHE   A CA   1 
ATOM   8892  C  C    . PHE   B 1 259 ? 29.111  -1.591  35.125  1.00 31.12  ?  258 PHE   A C    1 
ATOM   8893  O  O    . PHE   B 1 259 ? 28.557  -0.491  35.007  1.00 30.52  ?  258 PHE   A O    1 
ATOM   8894  C  CB   . PHE   B 1 259 ? 31.035  -2.487  33.701  1.00 29.83  ?  258 PHE   A CB   1 
ATOM   8895  C  CG   . PHE   B 1 259 ? 31.700  -1.161  33.800  1.00 29.76  ?  258 PHE   A CG   1 
ATOM   8896  C  CD1  . PHE   B 1 259 ? 31.573  -0.237  32.783  1.00 31.99  ?  258 PHE   A CD1  1 
ATOM   8897  C  CD2  . PHE   B 1 259 ? 32.396  -0.816  34.932  1.00 34.13  ?  258 PHE   A CD2  1 
ATOM   8898  C  CE1  . PHE   B 1 259 ? 32.150  0.996   32.887  1.00 33.09  ?  258 PHE   A CE1  1 
ATOM   8899  C  CE2  . PHE   B 1 259 ? 32.962  0.410   35.055  1.00 30.03  ?  258 PHE   A CE2  1 
ATOM   8900  C  CZ   . PHE   B 1 259 ? 32.831  1.339   34.045  1.00 27.44  ?  258 PHE   A CZ   1 
ATOM   8901  H  H    . PHE   B 1 259 ? 28.630  -0.974  32.906  1.00 32.17  ?  258 PHE   A H    1 
ATOM   8902  H  HA   . PHE   B 1 259 ? 29.214  -3.340  34.053  1.00 35.52  ?  258 PHE   A HA   1 
ATOM   8903  H  HB2  . PHE   B 1 259 ? 31.423  -3.067  34.375  1.00 35.79  ?  258 PHE   A HB2  1 
ATOM   8904  H  HB3  . PHE   B 1 259 ? 31.211  -2.844  32.816  1.00 35.79  ?  258 PHE   A HB3  1 
ATOM   8905  H  HD1  . PHE   B 1 259 ? 31.089  -0.456  32.020  1.00 38.38  ?  258 PHE   A HD1  1 
ATOM   8906  H  HD2  . PHE   B 1 259 ? 32.481  -1.432  35.623  1.00 40.95  ?  258 PHE   A HD2  1 
ATOM   8907  H  HE1  . PHE   B 1 259 ? 32.086  1.602   32.184  1.00 39.70  ?  258 PHE   A HE1  1 
ATOM   8908  H  HE2  . PHE   B 1 259 ? 33.440  0.625   35.824  1.00 36.03  ?  258 PHE   A HE2  1 
ATOM   8909  H  HZ   . PHE   B 1 259 ? 33.197  2.189   34.139  1.00 32.93  ?  258 PHE   A HZ   1 
ATOM   8910  N  N    . THR   B 1 260 ? 29.427  -2.117  36.296  1.00 35.00  ?  259 THR   A N    1 
ATOM   8911  C  CA   . THR   B 1 260 ? 29.209  -1.348  37.504  1.00 28.05  ?  259 THR   A CA   1 
ATOM   8912  C  C    . THR   B 1 260 ? 30.473  -0.581  37.874  1.00 29.58  ?  259 THR   A C    1 
ATOM   8913  O  O    . THR   B 1 260 ? 30.450  0.647   37.936  1.00 31.41  ?  259 THR   A O    1 
ATOM   8914  C  CB   . THR   B 1 260 ? 28.754  -2.248  38.652  1.00 31.26  ?  259 THR   A CB   1 
ATOM   8915  O  OG1  . THR   B 1 260 ? 27.413  -2.664  38.387  1.00 48.59  ?  259 THR   A OG1  1 
ATOM   8916  C  CG2  . THR   B 1 260 ? 28.860  -1.468  39.972  1.00 31.42  ?  259 THR   A CG2  1 
ATOM   8917  H  H    . THR   B 1 260 ? 29.761  -2.900  36.413  1.00 42.01  ?  259 THR   A H    1 
ATOM   8918  H  HA   . THR   B 1 260 ? 28.491  -0.714  37.351  1.00 33.65  ?  259 THR   A HA   1 
ATOM   8919  H  HB   . THR   B 1 260 ? 29.307  -3.040  38.740  1.00 37.52  ?  259 THR   A HB   1 
ATOM   8920  H  HG1  . THR   B 1 260 ? 27.187  -3.266  38.927  1.00 58.31  ?  259 THR   A HG1  1 
ATOM   8921  H  HG21 . THR   B 1 260 ? 28.549  -2.018  40.708  1.00 37.70  ?  259 THR   A HG21 1 
ATOM   8922  H  HG22 . THR   B 1 260 ? 29.783  -1.216  40.135  1.00 37.70  ?  259 THR   A HG22 1 
ATOM   8923  H  HG23 . THR   B 1 260 ? 28.318  -0.665  39.928  1.00 37.70  ?  259 THR   A HG23 1 
ATOM   8924  N  N    . CYS   B 1 261 ? 31.543  -1.284  38.225  1.00 24.01  ?  260 CYS   A N    1 
ATOM   8925  C  CA   . CYS   B 1 261 ? 32.816  -0.619  38.488  1.00 31.31  ?  260 CYS   A CA   1 
ATOM   8926  C  C    . CYS   B 1 261 ? 33.997  -1.500  38.079  1.00 27.10  ?  260 CYS   A C    1 
ATOM   8927  O  O    . CYS   B 1 261 ? 33.854  -2.690  37.793  1.00 28.79  ?  260 CYS   A O    1 
ATOM   8928  C  CB   . CYS   B 1 261 ? 32.922  -0.210  39.953  1.00 28.79  ?  260 CYS   A CB   1 
ATOM   8929  S  SG   . CYS   B 1 261 ? 32.716  -1.552  41.066  1.00 33.01  ?  260 CYS   A SG   1 
ATOM   8930  H  H    . CYS   B 1 261 ? 31.559  -2.139  38.317  1.00 28.81  ?  260 CYS   A H    1 
ATOM   8931  H  HA   . CYS   B 1 261 ? 32.860  0.172   37.928  1.00 37.57  ?  260 CYS   A HA   1 
ATOM   8932  H  HB2  . CYS   B 1 261 ? 33.799  0.174   40.108  1.00 34.55  ?  260 CYS   A HB2  1 
ATOM   8933  H  HB3  . CYS   B 1 261 ? 32.234  0.446   40.146  1.00 34.55  ?  260 CYS   A HB3  1 
ATOM   8934  H  HG   . CYS   B 1 261 ? 32.564  -1.120  42.175  1.00 39.61  ?  260 CYS   A HG   1 
ATOM   8935  N  N    . ALA   B 1 262 ? 35.178  -0.886  38.044  1.00 26.99  ?  261 ALA   A N    1 
ATOM   8936  C  CA   . ALA   B 1 262 ? 36.391  -1.555  37.585  1.00 27.18  ?  261 ALA   A CA   1 
ATOM   8937  C  C    . ALA   B 1 262 ? 37.614  -1.026  38.306  1.00 25.85  ?  261 ALA   A C    1 
ATOM   8938  O  O    . ALA   B 1 262 ? 37.595  0.054   38.915  1.00 27.61  ?  261 ALA   A O    1 
ATOM   8939  C  CB   . ALA   B 1 262 ? 36.548  -1.391  36.064  1.00 24.24  ?  261 ALA   A CB   1 
ATOM   8940  H  H    . ALA   B 1 262 ? 35.304  -0.070  38.285  1.00 32.39  ?  261 ALA   A H    1 
ATOM   8941  H  HA   . ALA   B 1 262 ? 36.332  -2.497  37.811  1.00 32.62  ?  261 ALA   A HA   1 
ATOM   8942  H  HB1  . ALA   B 1 262 ? 37.430  -1.698  35.802  1.00 29.09  ?  261 ALA   A HB1  1 
ATOM   8943  H  HB2  . ALA   B 1 262 ? 35.868  -1.920  35.617  1.00 29.09  ?  261 ALA   A HB2  1 
ATOM   8944  H  HB3  . ALA   B 1 262 ? 36.442  -0.454  35.834  1.00 29.09  ?  261 ALA   A HB3  1 
ATOM   8945  N  N    . SER   B 1 263 ? 38.667  -1.853  38.259  1.00 33.41  ?  262 SER   A N    1 
ATOM   8946  C  CA   . SER   B 1 263 ? 39.982  -1.583  38.867  1.00 29.32  ?  262 SER   A CA   1 
ATOM   8947  C  C    . SER   B 1 263 ? 41.001  -1.305  37.771  1.00 29.54  ?  262 SER   A C    1 
ATOM   8948  O  O    . SER   B 1 263 ? 41.249  -2.175  36.919  1.00 27.03  ?  262 SER   A O    1 
ATOM   8949  C  CB   . SER   B 1 263 ? 40.510  -2.764  39.680  1.00 29.68  ?  262 SER   A CB   1 
ATOM   8950  O  OG   . SER   B 1 263 ? 39.600  -3.154  40.687  1.00 33.12  ?  262 SER   A OG   1 
ATOM   8951  H  H    . SER   B 1 263 ? 38.645  -2.615  37.861  1.00 40.10  ?  262 SER   A H    1 
ATOM   8952  H  HA   . SER   B 1 263 ? 39.869  -0.811  39.444  1.00 35.18  ?  262 SER   A HA   1 
ATOM   8953  H  HB2  . SER   B 1 263 ? 40.654  -3.514  39.082  1.00 35.62  ?  262 SER   A HB2  1 
ATOM   8954  H  HB3  . SER   B 1 263 ? 41.347  -2.507  40.097  1.00 35.62  ?  262 SER   A HB3  1 
ATOM   8955  H  HG   . SER   B 1 263 ? 39.865  -3.862  41.055  1.00 39.75  ?  262 SER   A HG   1 
ATOM   8956  N  N    . GLU   B 1 264 ? 41.582  -0.106  37.784  1.00 29.73  ?  263 GLU   A N    1 
ATOM   8957  C  CA   . GLU   B 1 264 ? 42.657  0.231   36.875  1.00 33.63  ?  263 GLU   A CA   1 
ATOM   8958  C  C    . GLU   B 1 264 ? 43.949  -0.040  37.623  1.00 27.92  ?  263 GLU   A C    1 
ATOM   8959  O  O    . GLU   B 1 264 ? 44.075  0.315   38.799  1.00 31.39  ?  263 GLU   A O    1 
ATOM   8960  C  CB   . GLU   B 1 264 ? 42.581  1.686   36.419  1.00 35.86  ?  263 GLU   A CB   1 
ATOM   8961  C  CG   . GLU   B 1 264 ? 43.841  2.137   35.614  1.00 28.70  ?  263 GLU   A CG   1 
ATOM   8962  C  CD   . GLU   B 1 264 ? 43.982  3.655   35.624  1.00 37.04  ?  263 GLU   A CD   1 
ATOM   8963  O  OE1  . GLU   B 1 264 ? 44.867  4.146   36.345  1.00 44.57  ?  263 GLU   A OE1  1 
ATOM   8964  O  OE2  . GLU   B 1 264 ? 43.199  4.376   34.950  1.00 42.29  ?  263 GLU   A OE2  1 
ATOM   8965  H  H    . GLU   B 1 264 ? 41.363  0.531   38.318  1.00 35.67  ?  263 GLU   A H    1 
ATOM   8966  H  HA   . GLU   B 1 264 ? 42.612  -0.302  36.065  1.00 40.36  ?  263 GLU   A HA   1 
ATOM   8967  H  HB2  . GLU   B 1 264 ? 41.805  1.797   35.848  1.00 43.04  ?  263 GLU   A HB2  1 
ATOM   8968  H  HB3  . GLU   B 1 264 ? 42.503  2.257   37.199  1.00 43.04  ?  263 GLU   A HB3  1 
ATOM   8969  H  HG2  . GLU   B 1 264 ? 44.636  1.752   36.016  1.00 34.45  ?  263 GLU   A HG2  1 
ATOM   8970  H  HG3  . GLU   B 1 264 ? 43.759  1.842   34.694  1.00 34.45  ?  263 GLU   A HG3  1 
ATOM   8971  N  N    . TYR   B 1 265 ? 44.876  -0.714  36.966  1.00 27.77  ?  264 TYR   A N    1 
ATOM   8972  C  CA   . TYR   B 1 265 ? 46.209  -0.938  37.533  1.00 29.46  ?  264 TYR   A CA   1 
ATOM   8973  C  C    . TYR   B 1 265 ? 47.267  -0.460  36.564  1.00 26.25  ?  264 TYR   A C    1 
ATOM   8974  O  O    . TYR   B 1 265 ? 47.390  -1.003  35.466  1.00 31.40  ?  264 TYR   A O    1 
ATOM   8975  C  CB   . TYR   B 1 265 ? 46.458  -2.411  37.835  1.00 24.30  ?  264 TYR   A CB   1 
ATOM   8976  C  CG   . TYR   B 1 265 ? 47.719  -2.695  38.641  1.00 31.72  ?  264 TYR   A CG   1 
ATOM   8977  C  CD1  . TYR   B 1 265 ? 47.732  -2.488  40.013  1.00 28.39  ?  264 TYR   A CD1  1 
ATOM   8978  C  CD2  . TYR   B 1 265 ? 48.885  -3.151  38.027  1.00 31.29  ?  264 TYR   A CD2  1 
ATOM   8979  C  CE1  . TYR   B 1 265 ? 48.838  -2.722  40.755  1.00 27.24  ?  264 TYR   A CE1  1 
ATOM   8980  C  CE2  . TYR   B 1 265 ? 50.080  -3.388  38.781  1.00 28.13  ?  264 TYR   A CE2  1 
ATOM   8981  C  CZ   . TYR   B 1 265 ? 50.023  -3.174  40.135  1.00 31.26  ?  264 TYR   A CZ   1 
ATOM   8982  O  OH   . TYR   B 1 265 ? 51.091  -3.438  40.949  1.00 21.80  ?  264 TYR   A OH   1 
ATOM   8983  H  H    . TYR   B 1 265 ? 44.764  -1.057  36.185  1.00 33.32  ?  264 TYR   A H    1 
ATOM   8984  H  HA   . TYR   B 1 265 ? 46.269  -0.421  38.352  1.00 35.35  ?  264 TYR   A HA   1 
ATOM   8985  H  HB2  . TYR   B 1 265 ? 45.705  -2.752  38.343  1.00 29.16  ?  264 TYR   A HB2  1 
ATOM   8986  H  HB3  . TYR   B 1 265 ? 46.535  -2.888  36.995  1.00 29.16  ?  264 TYR   A HB3  1 
ATOM   8987  H  HD1  . TYR   B 1 265 ? 46.961  -2.181  40.432  1.00 34.07  ?  264 TYR   A HD1  1 
ATOM   8988  H  HD2  . TYR   B 1 265 ? 48.887  -3.304  37.109  1.00 37.55  ?  264 TYR   A HD2  1 
ATOM   8989  H  HE1  . TYR   B 1 265 ? 48.818  -2.585  41.675  1.00 32.69  ?  264 TYR   A HE1  1 
ATOM   8990  H  HE2  . TYR   B 1 265 ? 50.863  -3.675  38.369  1.00 33.75  ?  264 TYR   A HE2  1 
ATOM   8991  H  HH   . TYR   B 1 265 ? 51.805  -3.402  40.507  1.00 26.16  ?  264 TYR   A HH   1 
ATOM   8992  N  N    . THR   B 1 266 ? 48.086  0.483   37.003  1.00 32.09  ?  265 THR   A N    1 
ATOM   8993  C  CA   . THR   B 1 266 ? 49.275  0.902   36.269  1.00 32.09  ?  265 THR   A CA   1 
ATOM   8994  C  C    . THR   B 1 266 ? 50.569  0.547   37.018  1.00 36.66  ?  265 THR   A C    1 
ATOM   8995  O  O    . THR   B 1 266 ? 50.633  0.628   38.253  1.00 26.98  ?  265 THR   A O    1 
ATOM   8996  C  CB   . THR   B 1 266 ? 49.224  2.409   36.020  1.00 32.06  ?  265 THR   A CB   1 
ATOM   8997  O  OG1  . THR   B 1 266 ? 49.155  3.075   37.283  1.00 46.82  ?  265 THR   A OG1  1 
ATOM   8998  C  CG2  . THR   B 1 266 ? 47.988  2.800   35.234  1.00 38.20  ?  265 THR   A CG2  1 
ATOM   8999  H  H    . THR   B 1 266 ? 47.973  0.908   37.743  1.00 38.50  ?  265 THR   A H    1 
ATOM   9000  H  HA   . THR   B 1 266 ? 49.306  0.427   35.424  1.00 38.51  ?  265 THR   A HA   1 
ATOM   9001  H  HB   . THR   B 1 266 ? 50.010  2.672   35.516  1.00 38.47  ?  265 THR   A HB   1 
ATOM   9002  H  HG1  . THR   B 1 266 ? 48.360  3.099   37.552  1.00 56.19  ?  265 THR   A HG1  1 
ATOM   9003  H  HG21 . THR   B 1 266 ? 47.818  3.749   35.333  1.00 45.83  ?  265 THR   A HG21 1 
ATOM   9004  H  HG22 . THR   B 1 266 ? 48.116  2.600   34.293  1.00 45.83  ?  265 THR   A HG22 1 
ATOM   9005  H  HG23 . THR   B 1 266 ? 47.219  2.306   35.558  1.00 45.83  ?  265 THR   A HG23 1 
ATOM   9006  N  N    . GLY   B 1 267 ? 51.615  0.146   36.262  1.00 34.46  ?  266 GLY   A N    1 
ATOM   9007  C  CA   . GLY   B 1 267 ? 52.900  -0.218  36.844  1.00 27.68  ?  266 GLY   A CA   1 
ATOM   9008  C  C    . GLY   B 1 267 ? 53.166  -1.709  36.781  1.00 30.86  ?  266 GLY   A C    1 
ATOM   9009  O  O    . GLY   B 1 267 ? 52.492  -2.473  36.086  1.00 35.03  ?  266 GLY   A O    1 
ATOM   9010  H  H    . GLY   B 1 267 ? 51.591  0.081   35.405  1.00 41.35  ?  266 GLY   A H    1 
ATOM   9011  H  HA2  . GLY   B 1 267 ? 53.609  0.238   36.365  1.00 33.22  ?  266 GLY   A HA2  1 
ATOM   9012  H  HA3  . GLY   B 1 267 ? 52.920  0.056   37.774  1.00 33.22  ?  266 GLY   A HA3  1 
ATOM   9013  N  N    . ASN   B 1 268 ? 54.143  -2.120  37.564  1.00 30.45  ?  267 ASN   A N    1 
ATOM   9014  C  CA   . ASN   B 1 268 ? 54.633  -3.479  37.505  1.00 32.04  ?  267 ASN   A CA   1 
ATOM   9015  C  C    . ASN   B 1 268 ? 53.966  -4.314  38.585  1.00 29.72  ?  267 ASN   A C    1 
ATOM   9016  O  O    . ASN   B 1 268 ? 53.537  -3.804  39.618  1.00 26.34  ?  267 ASN   A O    1 
ATOM   9017  C  CB   . ASN   B 1 268 ? 56.153  -3.553  37.717  1.00 34.72  ?  267 ASN   A CB   1 
ATOM   9018  C  CG   . ASN   B 1 268 ? 56.918  -3.298  36.479  1.00 47.58  ?  267 ASN   A CG   1 
ATOM   9019  O  OD1  . ASN   B 1 268 ? 56.891  -2.178  35.960  1.00 45.37  ?  267 ASN   A OD1  1 
ATOM   9020  N  ND2  . ASN   B 1 268 ? 57.643  -4.329  35.994  1.00 42.34  ?  267 ASN   A ND2  1 
ATOM   9021  H  H    . ASN   B 1 268 ? 54.541  -1.625  38.144  1.00 36.54  ?  267 ASN   A H    1 
ATOM   9022  H  HA   . ASN   B 1 268 ? 54.432  -3.834  36.625  1.00 38.45  ?  267 ASN   A HA   1 
ATOM   9023  H  HB2  . ASN   B 1 268 ? 56.413  -2.887  38.372  1.00 41.66  ?  267 ASN   A HB2  1 
ATOM   9024  H  HB3  . ASN   B 1 268 ? 56.385  -4.439  38.035  1.00 41.66  ?  267 ASN   A HB3  1 
ATOM   9025  H  HD21 . ASN   B 1 268 ? 57.642  -5.085  36.404  1.00 50.81  ?  267 ASN   A HD21 1 
ATOM   9026  H  HD22 . ASN   B 1 268 ? 58.105  -4.229  35.276  1.00 50.81  ?  267 ASN   A HD22 1 
ATOM   9027  N  N    . TYR   B 1 269 ? 53.969  -5.624  38.358  1.00 29.26  ?  268 TYR   A N    1 
ATOM   9028  C  CA   . TYR   B 1 269 ? 53.574  -6.629  39.325  1.00 26.16  ?  268 TYR   A CA   1 
ATOM   9029  C  C    . TYR   B 1 269 ? 53.977  -6.268  40.755  1.00 33.13  ?  268 TYR   A C    1 
ATOM   9030  O  O    . TYR   B 1 269 ? 55.140  -6.039  41.053  1.00 27.43  ?  268 TYR   A O    1 
ATOM   9031  C  CB   . TYR   B 1 269 ? 54.189  -7.955  38.896  1.00 27.73  ?  268 TYR   A CB   1 
ATOM   9032  C  CG   . TYR   B 1 269 ? 53.576  -9.155  39.553  1.00 26.48  ?  268 TYR   A CG   1 
ATOM   9033  C  CD1  . TYR   B 1 269 ? 54.346  -9.990  40.331  1.00 28.30  ?  268 TYR   A CD1  1 
ATOM   9034  C  CD2  . TYR   B 1 269 ? 52.220  -9.443  39.414  1.00 27.71  ?  268 TYR   A CD2  1 
ATOM   9035  C  CE1  . TYR   B 1 269 ? 53.799  -11.087 40.952  1.00 31.77  ?  268 TYR   A CE1  1 
ATOM   9036  C  CE2  . TYR   B 1 269 ? 51.661  -10.547 40.036  1.00 29.93  ?  268 TYR   A CE2  1 
ATOM   9037  C  CZ   . TYR   B 1 269 ? 52.465  -11.372 40.785  1.00 30.93  ?  268 TYR   A CZ   1 
ATOM   9038  O  OH   . TYR   B 1 269 ? 51.926  -12.464 41.407  1.00 39.20  ?  268 TYR   A OH   1 
ATOM   9039  H  H    . TYR   B 1 269 ? 54.210  -5.970  37.608  1.00 35.11  ?  268 TYR   A H    1 
ATOM   9040  H  HA   . TYR   B 1 269 ? 52.608  -6.709  39.337  1.00 31.39  ?  268 TYR   A HA   1 
ATOM   9041  H  HB2  . TYR   B 1 269 ? 54.077  -8.054  37.938  1.00 33.27  ?  268 TYR   A HB2  1 
ATOM   9042  H  HB3  . TYR   B 1 269 ? 55.133  -7.947  39.120  1.00 33.27  ?  268 TYR   A HB3  1 
ATOM   9043  H  HD1  . TYR   B 1 269 ? 55.251  -9.808  40.439  1.00 33.96  ?  268 TYR   A HD1  1 
ATOM   9044  H  HD2  . TYR   B 1 269 ? 51.683  -8.888  38.896  1.00 33.26  ?  268 TYR   A HD2  1 
ATOM   9045  H  HE1  . TYR   B 1 269 ? 54.331  -11.636 41.483  1.00 38.13  ?  268 TYR   A HE1  1 
ATOM   9046  H  HE2  . TYR   B 1 269 ? 50.753  -10.728 39.949  1.00 35.91  ?  268 TYR   A HE2  1 
ATOM   9047  H  HH   . TYR   B 1 269 ? 52.378  -12.660 42.087  1.00 47.04  ?  268 TYR   A HH   1 
ATOM   9048  N  N    . GLN   B 1 270 ? 52.984  -6.160  41.638  1.00 28.32  ?  269 GLN   A N    1 
ATOM   9049  C  CA   . GLN   B 1 270 ? 53.198  -6.006  43.065  1.00 27.64  ?  269 GLN   A CA   1 
ATOM   9050  C  C    . GLN   B 1 270 ? 53.835  -4.696  43.468  1.00 28.52  ?  269 GLN   A C    1 
ATOM   9051  O  O    . GLN   B 1 270 ? 54.270  -4.575  44.642  1.00 31.21  ?  269 GLN   A O    1 
ATOM   9052  C  CB   . GLN   B 1 270 ? 54.084  -7.097  43.666  1.00 30.52  ?  269 GLN   A CB   1 
ATOM   9053  C  CG   . GLN   B 1 270 ? 53.445  -8.471  43.475  1.00 35.49  ?  269 GLN   A CG   1 
ATOM   9054  C  CD   . GLN   B 1 270 ? 54.237  -9.587  44.137  1.00 42.04  ?  269 GLN   A CD   1 
ATOM   9055  O  OE1  . GLN   B 1 270 ? 53.643  -10.528 44.688  1.00 43.30  ?  269 GLN   A OE1  1 
ATOM   9056  N  NE2  . GLN   B 1 270 ? 55.588  -9.501  44.072  1.00 38.67  ?  269 GLN   A NE2  1 
ATOM   9057  H  H    . GLN   B 1 270 ? 52.153  -6.175  41.419  1.00 33.98  ?  269 GLN   A H    1 
ATOM   9058  H  HA   . GLN   B 1 270 ? 52.306  -6.055  43.442  1.00 33.17  ?  269 GLN   A HA   1 
ATOM   9059  H  HB2  . GLN   B 1 270 ? 54.948  -7.093  43.225  1.00 36.63  ?  269 GLN   A HB2  1 
ATOM   9060  H  HB3  . GLN   B 1 270 ? 54.196  -6.937  44.617  1.00 36.63  ?  269 GLN   A HB3  1 
ATOM   9061  H  HG2  . GLN   B 1 270 ? 52.556  -8.463  43.864  1.00 42.59  ?  269 GLN   A HG2  1 
ATOM   9062  H  HG3  . GLN   B 1 270 ? 53.391  -8.665  42.526  1.00 42.59  ?  269 GLN   A HG3  1 
ATOM   9063  H  HE21 . GLN   B 1 270 ? 56.076  -10.110 44.433  1.00 46.40  ?  269 GLN   A HE21 1 
ATOM   9064  H  HE22 . GLN   B 1 270 ? 55.957  -8.836  43.670  1.00 46.40  ?  269 GLN   A HE22 1 
ATOM   9065  N  N    . CYS   B 1 271 ? 53.865  -3.683  42.593  1.00 18.35  ?  270 CYS   A N    1 
ATOM   9066  C  CA   . CYS   B 1 271 ? 54.470  -2.430  43.029  1.00 25.13  ?  270 CYS   A CA   1 
ATOM   9067  C  C    . CYS   B 1 271 ? 53.932  -1.281  42.244  1.00 23.30  ?  270 CYS   A C    1 
ATOM   9068  O  O    . CYS   B 1 271 ? 54.629  -0.275  42.054  1.00 27.53  ?  270 CYS   A O    1 
ATOM   9069  C  CB   . CYS   B 1 271 ? 56.034  -2.499  42.912  1.00 31.76  ?  270 CYS   A CB   1 
ATOM   9070  S  SG   . CYS   B 1 271 ? 56.649  -2.968  41.279  1.00 40.54  ?  270 CYS   A SG   1 
ATOM   9071  H  H    . CYS   B 1 271 ? 53.558  -3.700  41.790  1.00 22.02  ?  270 CYS   A H    1 
ATOM   9072  H  HA   . CYS   B 1 271 ? 54.259  -2.274  43.962  1.00 30.16  ?  270 CYS   A HA   1 
ATOM   9073  H  HB2  . CYS   B 1 271 ? 56.398  -1.625  43.121  1.00 38.12  ?  270 CYS   A HB2  1 
ATOM   9074  H  HB3  . CYS   B 1 271 ? 56.362  -3.155  43.547  1.00 38.12  ?  270 CYS   A HB3  1 
ATOM   9075  N  N    . GLY   B 1 272 ? 52.715  -1.431  41.743  1.00 31.03  ?  271 GLY   A N    1 
ATOM   9076  C  CA   . GLY   B 1 272 ? 52.056  -0.458  40.935  1.00 29.08  ?  271 GLY   A CA   1 
ATOM   9077  C  C    . GLY   B 1 272 ? 51.119  0.459   41.690  1.00 28.51  ?  271 GLY   A C    1 
ATOM   9078  O  O    . GLY   B 1 272 ? 51.387  0.870   42.818  1.00 36.82  ?  271 GLY   A O    1 
ATOM   9079  H  H    . GLY   B 1 272 ? 52.236  -2.133  41.873  1.00 37.23  ?  271 GLY   A H    1 
ATOM   9080  H  HA2  . GLY   B 1 272 ? 52.726  0.094   40.503  1.00 34.89  ?  271 GLY   A HA2  1 
ATOM   9081  H  HA3  . GLY   B 1 272 ? 51.538  -0.916  40.255  1.00 34.89  ?  271 GLY   A HA3  1 
ATOM   9082  N  N    . HIS   B 1 273 ? 50.028  0.839   41.023  1.00 27.25  ?  272 HIS   A N    1 
ATOM   9083  C  CA   . HIS   B 1 273 ? 49.029  1.721   41.608  1.00 35.49  ?  272 HIS   A CA   1 
ATOM   9084  C  C    . HIS   B 1 273 ? 47.629  1.408   41.080  1.00 26.75  ?  272 HIS   A C    1 
ATOM   9085  O  O    . HIS   B 1 273 ? 47.426  1.260   39.875  1.00 24.94  ?  272 HIS   A O    1 
ATOM   9086  C  CB   . HIS   B 1 273 ? 49.360  3.182   41.315  1.00 34.13  ?  272 HIS   A CB   1 
ATOM   9087  C  CG   . HIS   B 1 273 ? 48.448  4.142   42.017  1.00 34.91  ?  272 HIS   A CG   1 
ATOM   9088  N  ND1  . HIS   B 1 273 ? 47.639  5.037   41.346  1.00 29.71  ?  272 HIS   A ND1  1 
ATOM   9089  C  CD2  . HIS   B 1 273 ? 48.212  4.336   43.340  1.00 34.31  ?  272 HIS   A CD2  1 
ATOM   9090  C  CE1  . HIS   B 1 273 ? 46.964  5.760   42.227  1.00 29.13  ?  272 HIS   A CE1  1 
ATOM   9091  N  NE2  . HIS   B 1 273 ? 47.288  5.351   43.443  1.00 37.20  ?  272 HIS   A NE2  1 
ATOM   9092  H  H    . HIS   B 1 273 ? 49.844  0.594   40.220  1.00 32.70  ?  272 HIS   A H    1 
ATOM   9093  H  HA   . HIS   B 1 273 ? 49.020  1.562   42.565  1.00 42.59  ?  272 HIS   A HA   1 
ATOM   9094  H  HB2  . HIS   B 1 273 ? 50.267  3.364   41.607  1.00 40.95  ?  272 HIS   A HB2  1 
ATOM   9095  H  HB3  . HIS   B 1 273 ? 49.280  3.337   40.361  1.00 40.95  ?  272 HIS   A HB3  1 
ATOM   9096  H  HD2  . HIS   B 1 273 ? 48.601  3.870   44.044  1.00 41.17  ?  272 HIS   A HD2  1 
ATOM   9097  H  HE1  . HIS   B 1 273 ? 46.362  6.440   42.024  1.00 34.96  ?  272 HIS   A HE1  1 
ATOM   9098  H  HE2  . HIS   B 1 273 ? 46.973  5.668   44.177  1.00 44.64  ?  272 HIS   A HE2  1 
ATOM   9099  N  N    . TYR   B 1 274 ? 46.667  1.327   41.984  1.00 29.66  ?  273 TYR   A N    1 
ATOM   9100  C  CA   . TYR   B 1 274 ? 45.276  1.074   41.625  1.00 24.66  ?  273 TYR   A CA   1 
ATOM   9101  C  C    . TYR   B 1 274 ? 44.479  2.360   41.596  1.00 22.89  ?  273 TYR   A C    1 
ATOM   9102  O  O    . TYR   B 1 274 ? 44.590  3.180   42.511  1.00 26.49  ?  273 TYR   A O    1 
ATOM   9103  C  CB   . TYR   B 1 274 ? 44.634  0.168   42.645  1.00 18.32  ?  273 TYR   A CB   1 
ATOM   9104  C  CG   . TYR   B 1 274 ? 44.883  -1.329  42.516  1.00 21.18  ?  273 TYR   A CG   1 
ATOM   9105  C  CD1  . TYR   B 1 274 ? 45.769  -1.981  43.343  1.00 20.64  ?  273 TYR   A CD1  1 
ATOM   9106  C  CD2  . TYR   B 1 274 ? 44.184  -2.064  41.631  1.00 23.09  ?  273 TYR   A CD2  1 
ATOM   9107  C  CE1  . TYR   B 1 274 ? 45.940  -3.293  43.268  1.00 18.32  ?  273 TYR   A CE1  1 
ATOM   9108  C  CE2  . TYR   B 1 274 ? 44.333  -3.387  41.550  1.00 27.56  ?  273 TYR   A CE2  1 
ATOM   9109  C  CZ   . TYR   B 1 274 ? 45.218  -4.010  42.352  1.00 26.63  ?  273 TYR   A CZ   1 
ATOM   9110  O  OH   . TYR   B 1 274 ? 45.373  -5.383  42.252  1.00 26.41  ?  273 TYR   A OH   1 
ATOM   9111  H  H    . TYR   B 1 274 ? 46.794  1.417   42.829  1.00 35.60  ?  273 TYR   A H    1 
ATOM   9112  H  HA   . TYR   B 1 274 ? 45.257  0.669   40.744  1.00 29.59  ?  273 TYR   A HA   1 
ATOM   9113  H  HB2  . TYR   B 1 274 ? 44.958  0.431   43.521  1.00 21.98  ?  273 TYR   A HB2  1 
ATOM   9114  H  HB3  . TYR   B 1 274 ? 43.674  0.297   42.594  1.00 21.98  ?  273 TYR   A HB3  1 
ATOM   9115  H  HD1  . TYR   B 1 274 ? 46.256  -1.491  43.966  1.00 24.77  ?  273 TYR   A HD1  1 
ATOM   9116  H  HD2  . TYR   B 1 274 ? 43.582  -1.640  41.062  1.00 27.71  ?  273 TYR   A HD2  1 
ATOM   9117  H  HE1  . TYR   B 1 274 ? 46.543  -3.722  43.832  1.00 21.99  ?  273 TYR   A HE1  1 
ATOM   9118  H  HE2  . TYR   B 1 274 ? 43.827  -3.877  40.942  1.00 33.07  ?  273 TYR   A HE2  1 
ATOM   9119  H  HH   . TYR   B 1 274 ? 44.751  -5.710  41.791  1.00 31.70  ?  273 TYR   A HH   1 
ATOM   9120  N  N    . LYS   B 1 275 ? 43.611  2.488   40.592  1.00 27.28  ?  274 LYS   A N    1 
ATOM   9121  C  CA   . LYS   B 1 275 ? 42.511  3.444   40.614  1.00 28.35  ?  274 LYS   A CA   1 
ATOM   9122  C  C    . LYS   B 1 275 ? 41.180  2.699   40.405  1.00 30.51  ?  274 LYS   A C    1 
ATOM   9123  O  O    . LYS   B 1 275 ? 41.141  1.517   40.026  1.00 26.82  ?  274 LYS   A O    1 
ATOM   9124  C  CB   . LYS   B 1 275 ? 42.682  4.519   39.536  1.00 35.06  ?  274 LYS   A CB   1 
ATOM   9125  C  CG   . LYS   B 1 275 ? 44.025  5.271   39.522  1.00 35.52  ?  274 LYS   A CG   1 
ATOM   9126  C  CD   . LYS   B 1 275 ? 43.936  6.322   38.359  1.00 41.38  ?  274 LYS   A CD   1 
ATOM   9127  C  CE   . LYS   B 1 275 ? 45.172  7.208   38.323  1.00 38.60  ?  274 LYS   A CE   1 
ATOM   9128  N  NZ   . LYS   B 1 275 ? 45.537  7.528   36.887  1.00 42.65  ?  274 LYS   A NZ   1 
ATOM   9129  H  H    . LYS   B 1 275 ? 43.643  2.020   39.871  1.00 32.74  ?  274 LYS   A H    1 
ATOM   9130  H  HA   . LYS   B 1 275 ? 42.492  3.884   41.478  1.00 34.02  ?  274 LYS   A HA   1 
ATOM   9131  H  HB2  . LYS   B 1 275 ? 42.584  4.094   38.670  1.00 42.08  ?  274 LYS   A HB2  1 
ATOM   9132  H  HB3  . LYS   B 1 275 ? 41.985  5.182   39.661  1.00 42.08  ?  274 LYS   A HB3  1 
ATOM   9133  H  HG2  . LYS   B 1 275 ? 44.167  5.729   40.365  1.00 42.62  ?  274 LYS   A HG2  1 
ATOM   9134  H  HG3  . LYS   B 1 275 ? 44.756  4.657   39.351  1.00 42.62  ?  274 LYS   A HG3  1 
ATOM   9135  H  HD2  . LYS   B 1 275 ? 43.867  5.859   37.510  1.00 49.66  ?  274 LYS   A HD2  1 
ATOM   9136  H  HD3  . LYS   B 1 275 ? 43.159  6.887   38.493  1.00 49.66  ?  274 LYS   A HD3  1 
ATOM   9137  H  HE2  . LYS   B 1 275 ? 44.993  8.039   38.791  1.00 46.31  ?  274 LYS   A HE2  1 
ATOM   9138  H  HE3  . LYS   B 1 275 ? 45.917  6.747   38.739  1.00 46.31  ?  274 LYS   A HE3  1 
ATOM   9139  H  HZ1  . LYS   B 1 275 ? 46.285  8.010   36.864  1.00 51.18  ?  274 LYS   A HZ1  1 
ATOM   9140  H  HZ2  . LYS   B 1 275 ? 45.664  6.775   36.431  1.00 51.18  ?  274 LYS   A HZ2  1 
ATOM   9141  H  HZ3  . LYS   B 1 275 ? 44.883  7.992   36.503  1.00 51.18  ?  274 LYS   A HZ3  1 
ATOM   9142  N  N    . HIS   B 1 276 ? 40.072  3.418   40.619  1.00 29.05  ?  275 HIS   A N    1 
ATOM   9143  C  CA   . HIS   B 1 276 ? 38.732  2.829   40.690  1.00 28.79  ?  275 HIS   A CA   1 
ATOM   9144  C  C    . HIS   B 1 276 ? 37.836  3.571   39.722  1.00 30.57  ?  275 HIS   A C    1 
ATOM   9145  O  O    . HIS   B 1 276 ? 37.653  4.784   39.837  1.00 34.92  ?  275 HIS   A O    1 
ATOM   9146  C  CB   . HIS   B 1 276 ? 38.150  2.903   42.108  1.00 30.76  ?  275 HIS   A CB   1 
ATOM   9147  C  CG   . HIS   B 1 276 ? 36.766  2.343   42.223  1.00 30.82  ?  275 HIS   A CG   1 
ATOM   9148  N  ND1  . HIS   B 1 276 ? 36.519  1.008   42.460  1.00 34.20  ?  275 HIS   A ND1  1 
ATOM   9149  C  CD2  . HIS   B 1 276 ? 35.548  2.941   42.140  1.00 35.21  ?  275 HIS   A CD2  1 
ATOM   9150  C  CE1  . HIS   B 1 276 ? 35.204  0.808   42.519  1.00 35.37  ?  275 HIS   A CE1  1 
ATOM   9151  N  NE2  . HIS   B 1 276 ? 34.595  1.963   42.321  1.00 32.98  ?  275 HIS   A NE2  1 
ATOM   9152  H  H    . HIS   B 1 276 ? 40.073  4.270   40.729  1.00 34.86  ?  275 HIS   A H    1 
ATOM   9153  H  HA   . HIS   B 1 276 ? 38.782  1.896   40.432  1.00 34.55  ?  275 HIS   A HA   1 
ATOM   9154  H  HB2  . HIS   B 1 276 ? 38.723  2.399   42.706  1.00 36.92  ?  275 HIS   A HB2  1 
ATOM   9155  H  HB3  . HIS   B 1 276 ? 38.117  3.832   42.383  1.00 36.92  ?  275 HIS   A HB3  1 
ATOM   9156  H  HD1  . HIS   B 1 276 ? 37.119  0.399   42.555  1.00 41.04  ?  275 HIS   A HD1  1 
ATOM   9157  H  HD2  . HIS   B 1 276 ? 35.387  3.845   41.988  1.00 42.25  ?  275 HIS   A HD2  1 
ATOM   9158  H  HE1  . HIS   B 1 276 ? 34.785  -0.007  42.674  1.00 42.44  ?  275 HIS   A HE1  1 
ATOM   9159  N  N    . ILE   B 1 277 ? 37.299  2.863   38.752  1.00 26.14  ?  276 ILE   A N    1 
ATOM   9160  C  CA   . ILE   B 1 277 ? 36.410  3.455   37.769  1.00 32.76  ?  276 ILE   A CA   1 
ATOM   9161  C  C    . ILE   B 1 277 ? 34.987  2.992   38.071  1.00 36.12  ?  276 ILE   A C    1 
ATOM   9162  O  O    . ILE   B 1 277 ? 34.743  1.788   38.225  1.00 27.68  ?  276 ILE   A O    1 
ATOM   9163  C  CB   . ILE   B 1 277 ? 36.829  3.050   36.354  1.00 34.82  ?  276 ILE   A CB   1 
ATOM   9164  C  CG1  . ILE   B 1 277 ? 38.116  3.756   35.928  1.00 40.59  ?  276 ILE   A CG1  1 
ATOM   9165  C  CG2  . ILE   B 1 277 ? 35.788  3.464   35.353  1.00 30.10  ?  276 ILE   A CG2  1 
ATOM   9166  C  CD1  . ILE   B 1 277 ? 39.295  3.091   36.396  1.00 35.54  ?  276 ILE   A CD1  1 
ATOM   9167  H  H    . ILE   B 1 277 ? 37.436  2.022   38.639  1.00 31.37  ?  276 ILE   A H    1 
ATOM   9168  H  HA   . ILE   B 1 277 ? 36.435  4.422   37.840  1.00 39.31  ?  276 ILE   A HA   1 
ATOM   9169  H  HB   . ILE   B 1 277 ? 36.948  2.088   36.377  1.00 41.79  ?  276 ILE   A HB   1 
ATOM   9170  H  HG12 . ILE   B 1 277 ? 38.153  3.787   34.959  1.00 48.70  ?  276 ILE   A HG12 1 
ATOM   9171  H  HG13 . ILE   B 1 277 ? 38.117  4.657   36.288  1.00 48.70  ?  276 ILE   A HG13 1 
ATOM   9172  H  HG21 . ILE   B 1 277 ? 36.112  3.266   34.460  1.00 36.12  ?  276 ILE   A HG21 1 
ATOM   9173  H  HG22 . ILE   B 1 277 ? 34.971  2.971   35.525  1.00 36.12  ?  276 ILE   A HG22 1 
ATOM   9174  H  HG23 . ILE   B 1 277 ? 35.626  4.416   35.442  1.00 36.12  ?  276 ILE   A HG23 1 
ATOM   9175  H  HD11 . ILE   B 1 277 ? 40.076  3.556   36.058  1.00 42.64  ?  276 ILE   A HD11 1 
ATOM   9176  H  HD12 . ILE   B 1 277 ? 39.299  3.099   37.365  1.00 42.64  ?  276 ILE   A HD12 1 
ATOM   9177  H  HD13 . ILE   B 1 277 ? 39.291  2.176   36.073  1.00 42.64  ?  276 ILE   A HD13 1 
ATOM   9178  N  N    . THR   B 1 278 ? 34.057  3.943   38.161  1.00 31.29  ?  277 THR   A N    1 
ATOM   9179  C  CA   . THR   B 1 278 ? 32.663  3.632   38.418  1.00 30.79  ?  277 THR   A CA   1 
ATOM   9180  C  C    . THR   B 1 278 ? 31.756  4.229   37.338  1.00 32.83  ?  277 THR   A C    1 
ATOM   9181  O  O    . THR   B 1 278 ? 32.009  5.301   36.788  1.00 31.84  ?  277 THR   A O    1 
ATOM   9182  C  CB   . THR   B 1 278 ? 32.232  4.147   39.773  1.00 33.54  ?  277 THR   A CB   1 
ATOM   9183  O  OG1  . THR   B 1 278 ? 30.895  3.691   40.023  1.00 46.95  ?  277 THR   A OG1  1 
ATOM   9184  C  CG2  . THR   B 1 278 ? 32.268  5.647   39.733  1.00 29.73  ?  277 THR   A CG2  1 
ATOM   9185  H  H    . THR   B 1 278 ? 34.217  4.783   38.074  1.00 37.55  ?  277 THR   A H    1 
ATOM   9186  H  HA   . THR   B 1 278 ? 32.552  2.669   38.394  1.00 36.94  ?  277 THR   A HA   1 
ATOM   9187  H  HB   . THR   B 1 278 ? 32.811  3.834   40.485  1.00 40.25  ?  277 THR   A HB   1 
ATOM   9188  H  HG1  . THR   B 1 278 ? 30.367  4.344   40.039  1.00 56.34  ?  277 THR   A HG1  1 
ATOM   9189  H  HG21 . THR   B 1 278 ? 32.162  6.005   40.628  1.00 35.67  ?  277 THR   A HG21 1 
ATOM   9190  H  HG22 . THR   B 1 278 ? 33.116  5.949   39.372  1.00 35.67  ?  277 THR   A HG22 1 
ATOM   9191  H  HG23 . THR   B 1 278 ? 31.551  5.982   39.173  1.00 35.67  ?  277 THR   A HG23 1 
ATOM   9192  N  N    . SER   B 1 279 ? 30.687  3.531   37.038  1.00 37.00  ?  278 SER   A N    1 
ATOM   9193  C  CA   . SER   B 1 279 ? 29.699  3.966   36.047  1.00 34.77  ?  278 SER   A CA   1 
ATOM   9194  C  C    . SER   B 1 279 ? 28.402  4.402   36.745  1.00 36.55  ?  278 SER   A C    1 
ATOM   9195  O  O    . SER   B 1 279 ? 27.672  3.559   37.300  1.00 30.45  ?  278 SER   A O    1 
ATOM   9196  C  CB   . SER   B 1 279 ? 29.420  2.833   35.066  1.00 32.91  ?  278 SER   A CB   1 
ATOM   9197  O  OG   . SER   B 1 279 ? 28.471  3.240   34.103  1.00 32.80  ?  278 SER   A OG   1 
ATOM   9198  H  H    . SER   B 1 279 ? 30.495  2.775   37.400  1.00 44.40  ?  278 SER   A H    1 
ATOM   9199  H  HA   . SER   B 1 279 ? 30.049  4.741   35.579  1.00 41.72  ?  278 SER   A HA   1 
ATOM   9200  H  HB2  . SER   B 1 279 ? 30.245  2.591   34.616  1.00 39.50  ?  278 SER   A HB2  1 
ATOM   9201  H  HB3  . SER   B 1 279 ? 29.072  2.069   35.552  1.00 39.50  ?  278 SER   A HB3  1 
ATOM   9202  H  HG   . SER   B 1 279 ? 27.801  2.734   34.128  1.00 39.36  ?  278 SER   A HG   1 
ATOM   9203  N  N    . LYS   B 1 280 ? 28.132  5.718   36.724  1.00 32.27  ?  279 LYS   A N    1 
ATOM   9204  C  CA   . LYS   B 1 280 ? 26.895  6.282   37.259  1.00 39.40  ?  279 LYS   A CA   1 
ATOM   9205  C  C    . LYS   B 1 280 ? 26.151  6.964   36.120  1.00 42.92  ?  279 LYS   A C    1 
ATOM   9206  O  O    . LYS   B 1 280 ? 25.718  6.286   35.172  1.00 39.96  ?  279 LYS   A O    1 
ATOM   9207  C  CB   . LYS   B 1 280 ? 27.207  7.216   38.408  1.00 37.00  ?  279 LYS   A CB   1 
ATOM   9208  C  CG   . LYS   B 1 280 ? 27.865  6.425   39.532  1.00 38.35  ?  279 LYS   A CG   1 
ATOM   9209  C  CD   . LYS   B 1 280 ? 27.626  7.038   40.882  1.00 37.43  ?  279 LYS   A CD   1 
ATOM   9210  C  CE   . LYS   B 1 280 ? 28.413  6.256   41.960  1.00 34.44  ?  279 LYS   A CE   1 
ATOM   9211  N  NZ   . LYS   B 1 280 ? 28.245  6.956   43.255  1.00 42.06  ?  279 LYS   A NZ   1 
ATOM   9212  H  H    . LYS   B 1 280 ? 28.663  6.311   36.398  1.00 38.72  ?  279 LYS   A H    1 
ATOM   9213  H  HA   . LYS   B 1 280 ? 26.312  5.600   37.628  1.00 47.28  ?  279 LYS   A HA   1 
ATOM   9214  H  HB2  . LYS   B 1 280 ? 27.817  7.910   38.112  1.00 44.40  ?  279 LYS   A HB2  1 
ATOM   9215  H  HB3  . LYS   B 1 280 ? 26.388  7.615   38.741  1.00 44.40  ?  279 LYS   A HB3  1 
ATOM   9216  H  HG2  . LYS   B 1 280 ? 27.503  5.525   39.541  1.00 46.02  ?  279 LYS   A HG2  1 
ATOM   9217  H  HG3  . LYS   B 1 280 ? 28.823  6.395   39.381  1.00 46.02  ?  279 LYS   A HG3  1 
ATOM   9218  H  HD2  . LYS   B 1 280 ? 27.928  7.959   40.882  1.00 44.92  ?  279 LYS   A HD2  1 
ATOM   9219  H  HD3  . LYS   B 1 280 ? 26.680  6.998   41.097  1.00 44.92  ?  279 LYS   A HD3  1 
ATOM   9220  H  HE2  . LYS   B 1 280 ? 28.066  5.354   42.038  1.00 41.33  ?  279 LYS   A HE2  1 
ATOM   9221  H  HE3  . LYS   B 1 280 ? 29.356  6.231   41.732  1.00 41.33  ?  279 LYS   A HE3  1 
ATOM   9222  H  HZ1  . LYS   B 1 280 ? 28.795  6.609   43.863  1.00 50.47  ?  279 LYS   A HZ1  1 
ATOM   9223  H  HZ2  . LYS   B 1 280 ? 28.430  7.821   43.160  1.00 50.47  ?  279 LYS   A HZ2  1 
ATOM   9224  H  HZ3  . LYS   B 1 280 ? 27.407  6.869   43.542  1.00 50.47  ?  279 LYS   A HZ3  1 
ATOM   9225  N  N    . GLU   B 1 281 ? 25.974  8.286   36.185  1.00 40.47  ?  280 GLU   A N    1 
ATOM   9226  C  CA   . GLU   B 1 281 ? 25.427  8.968   35.008  1.00 43.96  ?  280 GLU   A CA   1 
ATOM   9227  C  C    . GLU   B 1 281 ? 26.495  9.143   33.925  1.00 45.01  ?  280 GLU   A C    1 
ATOM   9228  O  O    . GLU   B 1 281 ? 26.172  9.364   32.744  1.00 45.27  ?  280 GLU   A O    1 
ATOM   9229  C  CB   . GLU   B 1 281 ? 24.818  10.317  35.408  1.00 39.07  ?  280 GLU   A CB   1 
ATOM   9230  C  CG   . GLU   B 1 281 ? 25.795  11.492  35.399  1.00 49.28  ?  280 GLU   A CG   1 
ATOM   9231  C  CD   . GLU   B 1 281 ? 26.565  11.612  36.712  1.00 55.20  ?  280 GLU   A CD   1 
ATOM   9232  O  OE1  . GLU   B 1 281 ? 27.235  12.651  36.975  1.00 49.62  ?  280 GLU   A OE1  1 
ATOM   9233  O  OE2  . GLU   B 1 281 ? 26.507  10.641  37.496  1.00 48.20  ?  280 GLU   A OE2  1 
ATOM   9234  H  H    . GLU   B 1 281 ? 26.153  8.785   36.862  1.00 48.57  ?  280 GLU   A H    1 
ATOM   9235  H  HA   . GLU   B 1 281 ? 24.701  8.447   34.631  1.00 52.75  ?  280 GLU   A HA   1 
ATOM   9236  H  HB2  . GLU   B 1 281 ? 24.104  10.528  34.786  1.00 46.88  ?  280 GLU   A HB2  1 
ATOM   9237  H  HB3  . GLU   B 1 281 ? 24.463  10.240  36.307  1.00 46.88  ?  280 GLU   A HB3  1 
ATOM   9238  H  HG2  . GLU   B 1 281 ? 26.437  11.367  34.683  1.00 59.13  ?  280 GLU   A HG2  1 
ATOM   9239  H  HG3  . GLU   B 1 281 ? 25.302  12.315  35.262  1.00 59.13  ?  280 GLU   A HG3  1 
ATOM   9240  N  N    . THR   B 1 282 ? 27.762  9.076   34.321  1.00 43.89  ?  281 THR   A N    1 
ATOM   9241  C  CA   . THR   B 1 282 ? 28.902  9.082   33.408  1.00 42.64  ?  281 THR   A CA   1 
ATOM   9242  C  C    . THR   B 1 282 ? 30.005  8.285   34.107  1.00 39.75  ?  281 THR   A C    1 
ATOM   9243  O  O    . THR   B 1 282 ? 29.807  7.739   35.200  1.00 34.49  ?  281 THR   A O    1 
ATOM   9244  C  CB   . THR   B 1 282 ? 29.297  10.515  33.015  1.00 36.54  ?  281 THR   A CB   1 
ATOM   9245  O  OG1  . THR   B 1 282 ? 30.412  10.477  32.116  1.00 51.20  ?  281 THR   A OG1  1 
ATOM   9246  C  CG2  . THR   B 1 282 ? 29.618  11.348  34.246  1.00 43.46  ?  281 THR   A CG2  1 
ATOM   9247  H  H    . THR   B 1 282 ? 27.998  9.024   35.146  1.00 52.67  ?  281 THR   A H    1 
ATOM   9248  H  HA   . THR   B 1 282 ? 28.694  8.639   32.570  1.00 51.17  ?  281 THR   A HA   1 
ATOM   9249  H  HB   . THR   B 1 282 ? 28.555  10.948  32.566  1.00 43.85  ?  281 THR   A HB   1 
ATOM   9250  H  HG1  . THR   B 1 282 ? 30.724  11.250  32.014  1.00 61.44  ?  281 THR   A HG1  1 
ATOM   9251  H  HG21 . THR   B 1 282 ? 29.806  12.263  33.987  1.00 52.15  ?  281 THR   A HG21 1 
ATOM   9252  H  HG22 . THR   B 1 282 ? 28.865  11.341  34.856  1.00 52.15  ?  281 THR   A HG22 1 
ATOM   9253  H  HG23 . THR   B 1 282 ? 30.394  10.983  34.700  1.00 52.15  ?  281 THR   A HG23 1 
ATOM   9254  N  N    . LEU   B 1 283 ? 31.137  8.135   33.435  1.00 36.01  ?  282 LEU   A N    1 
ATOM   9255  C  CA   . LEU   B 1 283 ? 32.285  7.451   34.026  1.00 39.69  ?  282 LEU   A CA   1 
ATOM   9256  C  C    . LEU   B 1 283 ? 33.003  8.395   34.978  1.00 38.25  ?  282 LEU   A C    1 
ATOM   9257  O  O    . LEU   B 1 283 ? 33.246  9.562   34.647  1.00 41.78  ?  282 LEU   A O    1 
ATOM   9258  C  CB   . LEU   B 1 283 ? 33.238  6.952   32.955  1.00 33.23  ?  282 LEU   A CB   1 
ATOM   9259  C  CG   . LEU   B 1 283 ? 32.586  6.058   31.899  1.00 41.86  ?  282 LEU   A CG   1 
ATOM   9260  C  CD1  . LEU   B 1 283 ? 33.598  5.613   30.840  1.00 41.31  ?  282 LEU   A CD1  1 
ATOM   9261  C  CD2  . LEU   B 1 283 ? 31.925  4.873   32.581  1.00 41.69  ?  282 LEU   A CD2  1 
ATOM   9262  H  H    . LEU   B 1 283 ? 31.270  8.420   32.634  1.00 43.21  ?  282 LEU   A H    1 
ATOM   9263  H  HA   . LEU   B 1 283 ? 31.976  6.677   34.523  1.00 47.63  ?  282 LEU   A HA   1 
ATOM   9264  H  HB2  . LEU   B 1 283 ? 33.617  7.719   32.498  1.00 39.88  ?  282 LEU   A HB2  1 
ATOM   9265  H  HB3  . LEU   B 1 283 ? 33.941  6.439   33.383  1.00 39.88  ?  282 LEU   A HB3  1 
ATOM   9266  H  HG   . LEU   B 1 283 ? 31.903  6.558   31.426  1.00 50.23  ?  282 LEU   A HG   1 
ATOM   9267  H  HD11 . LEU   B 1 283 ? 33.142  5.073   30.175  1.00 49.57  ?  282 LEU   A HD11 1 
ATOM   9268  H  HD12 . LEU   B 1 283 ? 33.982  6.399   30.421  1.00 49.57  ?  282 LEU   A HD12 1 
ATOM   9269  H  HD13 . LEU   B 1 283 ? 34.295  5.091   31.267  1.00 49.57  ?  282 LEU   A HD13 1 
ATOM   9270  H  HD21 . LEU   B 1 283 ? 31.740  4.190   31.917  1.00 50.03  ?  282 LEU   A HD21 1 
ATOM   9271  H  HD22 . LEU   B 1 283 ? 32.525  4.523   33.258  1.00 50.03  ?  282 LEU   A HD22 1 
ATOM   9272  H  HD23 . LEU   B 1 283 ? 31.098  5.167   32.993  1.00 50.03  ?  282 LEU   A HD23 1 
ATOM   9273  N  N    . TYR   B 1 284 ? 33.279  7.910   36.183  1.00 31.56  ?  283 TYR   A N    1 
ATOM   9274  C  CA   . TYR   B 1 284 ? 34.121  8.615   37.135  1.00 33.90  ?  283 TYR   A CA   1 
ATOM   9275  C  C    . TYR   B 1 284 ? 35.354  7.772   37.433  1.00 39.92  ?  283 TYR   A C    1 
ATOM   9276  O  O    . TYR   B 1 284 ? 35.247  6.549   37.566  1.00 38.78  ?  283 TYR   A O    1 
ATOM   9277  C  CB   . TYR   B 1 284 ? 33.388  8.886   38.425  1.00 29.40  ?  283 TYR   A CB   1 
ATOM   9278  C  CG   . TYR   B 1 284 ? 32.367  9.994   38.348  1.00 38.48  ?  283 TYR   A CG   1 
ATOM   9279  C  CD1  . TYR   B 1 284 ? 31.058  9.718   38.044  1.00 37.15  ?  283 TYR   A CD1  1 
ATOM   9280  C  CD2  . TYR   B 1 284 ? 32.716  11.322  38.591  1.00 40.04  ?  283 TYR   A CD2  1 
ATOM   9281  C  CE1  . TYR   B 1 284 ? 30.112  10.717  37.990  1.00 42.70  ?  283 TYR   A CE1  1 
ATOM   9282  C  CE2  . TYR   B 1 284 ? 31.764  12.327  38.540  1.00 43.48  ?  283 TYR   A CE2  1 
ATOM   9283  C  CZ   . TYR   B 1 284 ? 30.457  12.007  38.238  1.00 39.42  ?  283 TYR   A CZ   1 
ATOM   9284  O  OH   . TYR   B 1 284 ? 29.494  12.984  38.172  1.00 44.94  ?  283 TYR   A OH   1 
ATOM   9285  H  H    . TYR   B 1 284 ? 32.983  7.158   36.476  1.00 37.88  ?  283 TYR   A H    1 
ATOM   9286  H  HA   . TYR   B 1 284 ? 34.396  9.464   36.754  1.00 40.68  ?  283 TYR   A HA   1 
ATOM   9287  H  HB2  . TYR   B 1 284 ? 32.923  8.078   38.691  1.00 35.27  ?  283 TYR   A HB2  1 
ATOM   9288  H  HB3  . TYR   B 1 284 ? 34.037  9.133   39.102  1.00 35.27  ?  283 TYR   A HB3  1 
ATOM   9289  H  HD1  . TYR   B 1 284 ? 30.805  8.840   37.871  1.00 44.58  ?  283 TYR   A HD1  1 
ATOM   9290  H  HD2  . TYR   B 1 284 ? 33.599  11.536  38.789  1.00 48.05  ?  283 TYR   A HD2  1 
ATOM   9291  H  HE1  . TYR   B 1 284 ? 29.230  10.507  37.782  1.00 51.23  ?  283 TYR   A HE1  1 
ATOM   9292  H  HE2  . TYR   B 1 284 ? 32.003  13.210  38.708  1.00 52.18  ?  283 TYR   A HE2  1 
ATOM   9293  H  HH   . TYR   B 1 284 ? 29.764  13.680  38.557  1.00 53.93  ?  283 TYR   A HH   1 
ATOM   9294  N  N    . CYS   B 1 285 ? 36.524  8.420   37.519  1.00 37.94  ?  284 CYS   A N    1 
ATOM   9295  C  CA   . CYS   B 1 285 ? 37.751  7.792   38.015  1.00 32.62  ?  284 CYS   A CA   1 
ATOM   9296  C  C    . CYS   B 1 285 ? 38.045  8.291   39.438  1.00 31.79  ?  284 CYS   A C    1 
ATOM   9297  O  O    . CYS   B 1 285 ? 38.320  9.471   39.642  1.00 33.66  ?  284 CYS   A O    1 
ATOM   9298  C  CB   . CYS   B 1 285 ? 38.899  8.078   37.058  1.00 36.56  ?  284 CYS   A CB   1 
ATOM   9299  S  SG   . CYS   B 1 285 ? 40.329  7.210   37.620  1.00 42.40  ?  284 CYS   A SG   1 
ATOM   9300  H  H    . CYS   B 1 285 ? 36.631  9.242   37.290  1.00 45.53  ?  284 CYS   A H    1 
ATOM   9301  H  HA   . CYS   B 1 285 ? 37.625  6.832   38.079  1.00 39.15  ?  284 CYS   A HA   1 
ATOM   9302  H  HB2  . CYS   B 1 285 ? 38.671  7.771   36.167  1.00 43.88  ?  284 CYS   A HB2  1 
ATOM   9303  H  HB3  . CYS   B 1 285 ? 39.090  9.029   37.044  1.00 43.88  ?  284 CYS   A HB3  1 
ATOM   9304  H  HG   . CYS   B 1 285 ? 41.174  7.258   36.769  1.00 50.88  ?  284 CYS   A HG   1 
ATOM   9305  N  N    . ILE   B 1 286 ? 37.896  7.425   40.434  1.00 30.04  ?  285 ILE   A N    1 
ATOM   9306  C  CA   . ILE   B 1 286 ? 38.165  7.784   41.818  1.00 34.73  ?  285 ILE   A CA   1 
ATOM   9307  C  C    . ILE   B 1 286 ? 39.557  7.274   42.180  1.00 31.38  ?  285 ILE   A C    1 
ATOM   9308  O  O    . ILE   B 1 286 ? 39.818  6.065   42.181  1.00 31.09  ?  285 ILE   A O    1 
ATOM   9309  C  CB   . ILE   B 1 286 ? 37.097  7.223   42.769  1.00 34.83  ?  285 ILE   A CB   1 
ATOM   9310  C  CG1  . ILE   B 1 286 ? 35.703  7.735   42.381  1.00 35.01  ?  285 ILE   A CG1  1 
ATOM   9311  C  CG2  . ILE   B 1 286 ? 37.436  7.619   44.245  1.00 28.99  ?  285 ILE   A CG2  1 
ATOM   9312  C  CD1  . ILE   B 1 286 ? 34.602  7.025   43.044  1.00 40.21  ?  285 ILE   A CD1  1 
ATOM   9313  H  H    . ILE   B 1 286 ? 37.636  6.612   40.329  1.00 36.05  ?  285 ILE   A H    1 
ATOM   9314  H  HA   . ILE   B 1 286 ? 38.164  8.750   41.902  1.00 41.67  ?  285 ILE   A HA   1 
ATOM   9315  H  HB   . ILE   B 1 286 ? 37.095  6.256   42.695  1.00 41.80  ?  285 ILE   A HB   1 
ATOM   9316  H  HG12 . ILE   B 1 286 ? 35.638  8.672   42.622  1.00 42.02  ?  285 ILE   A HG12 1 
ATOM   9317  H  HG13 . ILE   B 1 286 ? 35.589  7.630   41.424  1.00 42.02  ?  285 ILE   A HG13 1 
ATOM   9318  H  HG21 . ILE   B 1 286 ? 36.680  7.403   44.812  1.00 34.79  ?  285 ILE   A HG21 1 
ATOM   9319  H  HG22 . ILE   B 1 286 ? 38.218  7.123   44.533  1.00 34.79  ?  285 ILE   A HG22 1 
ATOM   9320  H  HG23 . ILE   B 1 286 ? 37.616  8.571   44.283  1.00 34.79  ?  285 ILE   A HG23 1 
ATOM   9321  H  HD11 . ILE   B 1 286 ? 33.792  7.143   42.523  1.00 48.25  ?  285 ILE   A HD11 1 
ATOM   9322  H  HD12 . ILE   B 1 286 ? 34.823  6.083   43.102  1.00 48.25  ?  285 ILE   A HD12 1 
ATOM   9323  H  HD13 . ILE   B 1 286 ? 34.480  7.392   43.933  1.00 48.25  ?  285 ILE   A HD13 1 
ATOM   9324  N  N    . ASP   B 1 287 ? 40.459  8.203   42.461  1.00 36.97  ?  286 ASP   A N    1 
ATOM   9325  C  CA   . ASP   B 1 287 ? 41.873  7.927   42.725  1.00 28.17  ?  286 ASP   A CA   1 
ATOM   9326  C  C    . ASP   B 1 287 ? 42.145  8.424   44.126  1.00 27.59  ?  286 ASP   A C    1 
ATOM   9327  O  O    . ASP   B 1 287 ? 42.529  9.578   44.333  1.00 29.38  ?  286 ASP   A O    1 
ATOM   9328  C  CB   . ASP   B 1 287 ? 42.711  8.611   41.692  1.00 39.36  ?  286 ASP   A CB   1 
ATOM   9329  C  CG   . ASP   B 1 287 ? 44.188  8.226   41.765  1.00 38.44  ?  286 ASP   A CG   1 
ATOM   9330  O  OD1  . ASP   B 1 287 ? 44.611  7.543   42.746  1.00 33.88  ?  286 ASP   A OD1  1 
ATOM   9331  O  OD2  . ASP   B 1 287 ? 44.916  8.656   40.844  1.00 41.53  ?  286 ASP   A OD2  1 
ATOM   9332  H  H    . ASP   B 1 287 ? 40.272  9.041   42.507  1.00 44.36  ?  286 ASP   A H    1 
ATOM   9333  H  HA   . ASP   B 1 287 ? 42.069  6.977   42.696  1.00 33.81  ?  286 ASP   A HA   1 
ATOM   9334  H  HB2  . ASP   B 1 287 ? 42.383  8.370   40.812  1.00 47.24  ?  286 ASP   A HB2  1 
ATOM   9335  H  HB3  . ASP   B 1 287 ? 42.646  9.570   41.820  1.00 47.24  ?  286 ASP   A HB3  1 
ATOM   9336  N  N    . GLY   B 1 288 ? 41.904  7.557   45.101  1.00 27.64  ?  287 GLY   A N    1 
ATOM   9337  C  CA   . GLY   B 1 288 ? 42.033  7.947   46.493  1.00 29.80  ?  287 GLY   A CA   1 
ATOM   9338  C  C    . GLY   B 1 288 ? 41.141  9.136   46.781  1.00 36.63  ?  287 GLY   A C    1 
ATOM   9339  O  O    . GLY   B 1 288 ? 39.932  8.977   46.856  1.00 34.17  ?  287 GLY   A O    1 
ATOM   9340  H  H    . GLY   B 1 288 ? 41.665  6.740   44.980  1.00 33.17  ?  287 GLY   A H    1 
ATOM   9341  H  HA2  . GLY   B 1 288 ? 41.774  7.210   47.068  1.00 35.76  ?  287 GLY   A HA2  1 
ATOM   9342  H  HA3  . GLY   B 1 288 ? 42.953  8.188   46.685  1.00 35.76  ?  287 GLY   A HA3  1 
ATOM   9343  N  N    . ALA   B 1 289 ? 41.710  10.327  46.919  1.00 33.49  ?  288 ALA   A N    1 
ATOM   9344  C  CA   . ALA   B 1 289 ? 40.984  11.547  47.249  1.00 38.58  ?  288 ALA   A CA   1 
ATOM   9345  C  C    . ALA   B 1 289 ? 40.626  12.399  46.035  1.00 43.81  ?  288 ALA   A C    1 
ATOM   9346  O  O    . ALA   B 1 289 ? 39.912  13.402  46.189  1.00 40.53  ?  288 ALA   A O    1 
ATOM   9347  C  CB   . ALA   B 1 289 ? 41.840  12.402  48.200  1.00 34.37  ?  288 ALA   A CB   1 
ATOM   9348  H  H    . ALA   B 1 289 ? 42.554  10.461  46.822  1.00 40.18  ?  288 ALA   A H    1 
ATOM   9349  H  HA   . ALA   B 1 289 ? 40.156  11.300  47.689  1.00 46.30  ?  288 ALA   A HA   1 
ATOM   9350  H  HB1  . ALA   B 1 289 ? 41.341  13.195  48.447  1.00 41.24  ?  288 ALA   A HB1  1 
ATOM   9351  H  HB2  . ALA   B 1 289 ? 42.048  11.881  48.992  1.00 41.24  ?  288 ALA   A HB2  1 
ATOM   9352  H  HB3  . ALA   B 1 289 ? 42.660  12.654  47.747  1.00 41.24  ?  288 ALA   A HB3  1 
ATOM   9353  N  N    . LEU   B 1 290 ? 41.109  12.033  44.850  1.00 37.15  ?  289 LEU   A N    1 
ATOM   9354  C  CA   . LEU   B 1 290 ? 40.921  12.822  43.650  1.00 36.69  ?  289 LEU   A CA   1 
ATOM   9355  C  C    . LEU   B 1 290 ? 39.864  12.153  42.797  1.00 40.55  ?  289 LEU   A C    1 
ATOM   9356  O  O    . LEU   B 1 290 ? 39.820  10.921  42.731  1.00 36.11  ?  289 LEU   A O    1 
ATOM   9357  C  CB   . LEU   B 1 290 ? 42.210  12.921  42.849  1.00 35.77  ?  289 LEU   A CB   1 
ATOM   9358  C  CG   . LEU   B 1 290 ? 43.461  13.566  43.431  1.00 33.76  ?  289 LEU   A CG   1 
ATOM   9359  C  CD1  . LEU   B 1 290 ? 43.175  14.798  44.281  1.00 34.44  ?  289 LEU   A CD1  1 
ATOM   9360  C  CD2  . LEU   B 1 290 ? 44.272  12.508  44.225  1.00 41.53  ?  289 LEU   A CD2  1 
ATOM   9361  H  H    . LEU   B 1 290 ? 41.561  11.313  44.719  1.00 44.58  ?  289 LEU   A H    1 
ATOM   9362  H  HA   . LEU   B 1 290 ? 40.640  13.720  43.887  1.00 44.03  ?  289 LEU   A HA   1 
ATOM   9363  H  HB2  . LEU   B 1 290 ? 42.466  12.015  42.616  1.00 42.92  ?  289 LEU   A HB2  1 
ATOM   9364  H  HB3  . LEU   B 1 290 ? 42.004  13.424  42.046  1.00 42.92  ?  289 LEU   A HB3  1 
ATOM   9365  H  HG   . LEU   B 1 290 ? 43.997  13.892  42.691  1.00 40.51  ?  289 LEU   A HG   1 
ATOM   9366  H  HD11 . LEU   B 1 290 ? 44.007  15.118  44.664  1.00 41.33  ?  289 LEU   A HD11 1 
ATOM   9367  H  HD12 . LEU   B 1 290 ? 42.783  15.486  43.720  1.00 41.33  ?  289 LEU   A HD12 1 
ATOM   9368  H  HD13 . LEU   B 1 290 ? 42.556  14.557  44.989  1.00 41.33  ?  289 LEU   A HD13 1 
ATOM   9369  H  HD21 . LEU   B 1 290 ? 44.981  12.954  44.714  1.00 49.83  ?  289 LEU   A HD21 1 
ATOM   9370  H  HD22 . LEU   B 1 290 ? 43.678  12.055  44.845  1.00 49.83  ?  289 LEU   A HD22 1 
ATOM   9371  H  HD23 . LEU   B 1 290 ? 44.651  11.868  43.603  1.00 49.83  ?  289 LEU   A HD23 1 
ATOM   9372  N  N    . LEU   B 1 291 ? 39.037  12.976  42.134  1.00 39.19  ?  290 LEU   A N    1 
ATOM   9373  C  CA   . LEU   B 1 291 ? 37.972  12.557  41.235  1.00 34.81  ?  290 LEU   A CA   1 
ATOM   9374  C  C    . LEU   B 1 291 ? 38.206  13.114  39.837  1.00 32.12  ?  290 LEU   A C    1 
ATOM   9375  O  O    . LEU   B 1 291 ? 38.753  14.207  39.670  1.00 39.31  ?  290 LEU   A O    1 
ATOM   9376  C  CB   . LEU   B 1 291 ? 36.605  13.039  41.759  1.00 41.98  ?  290 LEU   A CB   1 
ATOM   9377  C  CG   . LEU   B 1 291 ? 35.333  12.735  40.964  1.00 34.61  ?  290 LEU   A CG   1 
ATOM   9378  C  CD1  . LEU   B 1 291 ? 35.284  11.181  40.847  1.00 38.24  ?  290 LEU   A CD1  1 
ATOM   9379  C  CD2  . LEU   B 1 291 ? 34.045  13.292  41.526  1.00 35.94  ?  290 LEU   A CD2  1 
ATOM   9380  H  H    . LEU   B 1 291 ? 39.082  13.833  42.200  1.00 47.02  ?  290 LEU   A H    1 
ATOM   9381  H  HA   . LEU   B 1 291 ? 37.965  11.589  41.170  1.00 41.77  ?  290 LEU   A HA   1 
ATOM   9382  H  HB2  . LEU   B 1 291 ? 36.478  12.643  42.635  1.00 50.38  ?  290 LEU   A HB2  1 
ATOM   9383  H  HB3  . LEU   B 1 291 ? 36.652  14.005  41.835  1.00 50.38  ?  290 LEU   A HB3  1 
ATOM   9384  H  HG   . LEU   B 1 291 ? 35.379  13.183  40.105  1.00 41.54  ?  290 LEU   A HG   1 
ATOM   9385  H  HD11 . LEU   B 1 291 ? 34.449  10.922  40.427  1.00 45.88  ?  290 LEU   A HD11 1 
ATOM   9386  H  HD12 . LEU   B 1 291 ? 36.033  10.881  40.308  1.00 45.88  ?  290 LEU   A HD12 1 
ATOM   9387  H  HD13 . LEU   B 1 291 ? 35.341  10.795  41.735  1.00 45.88  ?  290 LEU   A HD13 1 
ATOM   9388  H  HD21 . LEU   B 1 291 ? 33.307  13.009  40.963  1.00 43.13  ?  290 LEU   A HD21 1 
ATOM   9389  H  HD22 . LEU   B 1 291 ? 33.922  12.956  42.427  1.00 43.13  ?  290 LEU   A HD22 1 
ATOM   9390  H  HD23 . LEU   B 1 291 ? 34.099  14.260  41.538  1.00 43.13  ?  290 LEU   A HD23 1 
ATOM   9391  N  N    . THR   B 1 292 ? 37.842  12.338  38.821  1.00 36.34  ?  291 THR   A N    1 
ATOM   9392  C  CA   . THR   B 1 292 ? 37.827  12.892  37.473  1.00 42.23  ?  291 THR   A CA   1 
ATOM   9393  C  C    . THR   B 1 292 ? 36.681  12.276  36.678  1.00 41.13  ?  291 THR   A C    1 
ATOM   9394  O  O    . THR   B 1 292 ? 36.269  11.137  36.930  1.00 37.10  ?  291 THR   A O    1 
ATOM   9395  C  CB   . THR   B 1 292 ? 39.167  12.708  36.742  1.00 43.76  ?  291 THR   A CB   1 
ATOM   9396  O  OG1  . THR   B 1 292 ? 39.177  11.478  36.021  1.00 53.42  ?  291 THR   A OG1  1 
ATOM   9397  C  CG2  . THR   B 1 292 ? 40.302  12.729  37.733  1.00 41.60  ?  291 THR   A CG2  1 
ATOM   9398  H  H    . THR   B 1 292 ? 37.606  11.513  38.885  1.00 43.60  ?  291 THR   A H    1 
ATOM   9399  H  HA   . THR   B 1 292 ? 37.664  13.846  37.532  1.00 50.67  ?  291 THR   A HA   1 
ATOM   9400  H  HB   . THR   B 1 292 ? 39.291  13.433  36.110  1.00 52.52  ?  291 THR   A HB   1 
ATOM   9401  H  HG1  . THR   B 1 292 ? 39.865  11.432  35.540  1.00 64.11  ?  291 THR   A HG1  1 
ATOM   9402  H  HG21 . THR   B 1 292 ? 41.151  12.706  37.265  1.00 49.92  ?  291 THR   A HG21 1 
ATOM   9403  H  HG22 . THR   B 1 292 ? 40.260  13.537  38.268  1.00 49.92  ?  291 THR   A HG22 1 
ATOM   9404  H  HG23 . THR   B 1 292 ? 40.244  11.960  38.320  1.00 49.92  ?  291 THR   A HG23 1 
ATOM   9405  N  N    . LYS   B 1 293 ? 36.173  13.040  35.713  1.00 43.05  ?  292 LYS   A N    1 
ATOM   9406  C  CA   . LYS   B 1 293 ? 35.086  12.582  34.871  1.00 40.89  ?  292 LYS   A CA   1 
ATOM   9407  C  C    . LYS   B 1 293 ? 35.502  12.422  33.425  1.00 39.75  ?  292 LYS   A C    1 
ATOM   9408  O  O    . LYS   B 1 293 ? 36.414  13.102  32.952  1.00 56.19  ?  292 LYS   A O    1 
ATOM   9409  C  CB   . LYS   B 1 293 ? 33.917  13.555  34.861  1.00 51.14  ?  292 LYS   A CB   1 
ATOM   9410  C  CG   . LYS   B 1 293 ? 33.464  14.048  36.165  1.00 46.05  ?  292 LYS   A CG   1 
ATOM   9411  C  CD   . LYS   B 1 293 ? 31.970  14.294  36.042  1.00 55.28  ?  292 LYS   A CD   1 
ATOM   9412  C  CE   . LYS   B 1 293 ? 31.650  15.503  35.166  1.00 49.96  ?  292 LYS   A CE   1 
ATOM   9413  N  NZ   . LYS   B 1 293 ? 30.446  16.257  35.683  1.00 59.29  ?  292 LYS   A NZ   1 
ATOM   9414  H  H    . LYS   B 1 293 ? 36.449  13.834  35.530  1.00 51.66  ?  292 LYS   A H    1 
ATOM   9415  H  HA   . LYS   B 1 293 ? 34.817  11.722  35.232  1.00 49.07  ?  292 LYS   A HA   1 
ATOM   9416  H  HB2  . LYS   B 1 293 ? 34.175  14.331  34.339  1.00 61.37  ?  292 LYS   A HB2  1 
ATOM   9417  H  HB3  . LYS   B 1 293 ? 33.160  13.113  34.446  1.00 61.37  ?  292 LYS   A HB3  1 
ATOM   9418  H  HG2  . LYS   B 1 293 ? 33.628  13.385  36.854  1.00 55.26  ?  292 LYS   A HG2  1 
ATOM   9419  H  HG3  . LYS   B 1 293 ? 33.913  14.878  36.389  1.00 55.26  ?  292 LYS   A HG3  1 
ATOM   9420  H  HD2  . LYS   B 1 293 ? 31.551  13.515  35.645  1.00 66.33  ?  292 LYS   A HD2  1 
ATOM   9421  H  HD3  . LYS   B 1 293 ? 31.601  14.455  36.925  1.00 66.33  ?  292 LYS   A HD3  1 
ATOM   9422  H  HE2  . LYS   B 1 293 ? 32.409  16.107  35.161  1.00 59.95  ?  292 LYS   A HE2  1 
ATOM   9423  H  HE3  . LYS   B 1 293 ? 31.458  15.204  34.264  1.00 59.95  ?  292 LYS   A HE3  1 
ATOM   9424  H  HZ1  . LYS   B 1 293 ? 30.307  16.985  35.190  1.00 71.14  ?  292 LYS   A HZ1  1 
ATOM   9425  H  HZ2  . LYS   B 1 293 ? 29.723  15.740  35.645  1.00 71.14  ?  292 LYS   A HZ2  1 
ATOM   9426  H  HZ3  . LYS   B 1 293 ? 30.581  16.503  36.528  1.00 71.14  ?  292 LYS   A HZ3  1 
ATOM   9427  N  N    . SER   B 1 294 ? 34.766  11.575  32.707  1.00 42.55  ?  293 SER   A N    1 
ATOM   9428  C  CA   . SER   B 1 294 ? 34.908  11.441  31.266  1.00 43.16  ?  293 SER   A CA   1 
ATOM   9429  C  C    . SER   B 1 294 ? 33.750  10.607  30.731  1.00 48.81  ?  293 SER   A C    1 
ATOM   9430  O  O    . SER   B 1 294 ? 33.131  9.812   31.455  1.00 46.04  ?  293 SER   A O    1 
ATOM   9431  C  CB   . SER   B 1 294 ? 36.245  10.807  30.889  1.00 47.06  ?  293 SER   A CB   1 
ATOM   9432  O  OG   . SER   B 1 294 ? 36.321  9.492   31.402  1.00 47.09  ?  293 SER   A OG   1 
ATOM   9433  H  H    . SER   B 1 294 ? 34.166  11.058  33.041  1.00 51.06  ?  293 SER   A H    1 
ATOM   9434  H  HA   . SER   B 1 294 ? 34.858  12.320  30.859  1.00 51.79  ?  293 SER   A HA   1 
ATOM   9435  H  HB2  . SER   B 1 294 ? 36.322  10.777  29.923  1.00 56.47  ?  293 SER   A HB2  1 
ATOM   9436  H  HB3  . SER   B 1 294 ? 36.966  11.337  31.263  1.00 56.47  ?  293 SER   A HB3  1 
ATOM   9437  H  HG   . SER   B 1 294 ? 37.102  9.196   31.318  1.00 56.51  ?  293 SER   A HG   1 
ATOM   9438  N  N    . SER   B 1 295 ? 33.468  10.815  29.436  1.00 50.50  ?  294 SER   A N    1 
ATOM   9439  C  CA   . SER   B 1 295 ? 32.446  10.053  28.733  1.00 47.64  ?  294 SER   A CA   1 
ATOM   9440  C  C    . SER   B 1 295 ? 32.958  8.687   28.324  1.00 50.21  ?  294 SER   A C    1 
ATOM   9441  O  O    . SER   B 1 295 ? 32.183  7.721   28.246  1.00 50.40  ?  294 SER   A O    1 
ATOM   9442  C  CB   . SER   B 1 295 ? 32.005  10.812  27.481  1.00 50.08  ?  294 SER   A CB   1 
ATOM   9443  O  OG   . SER   B 1 295 ? 32.025  12.201  27.740  1.00 58.96  ?  294 SER   A OG   1 
ATOM   9444  H  H    . SER   B 1 295 ? 33.862  11.398  28.943  1.00 60.60  ?  294 SER   A H    1 
ATOM   9445  H  HA   . SER   B 1 295 ? 31.679  9.942   29.316  1.00 57.17  ?  294 SER   A HA   1 
ATOM   9446  H  HB2  . SER   B 1 295 ? 32.614  10.612  26.753  1.00 60.10  ?  294 SER   A HB2  1 
ATOM   9447  H  HB3  . SER   B 1 295 ? 31.104  10.543  27.243  1.00 60.10  ?  294 SER   A HB3  1 
ATOM   9448  H  HG   . SER   B 1 295 ? 31.784  12.624  27.056  1.00 70.75  ?  294 SER   A HG   1 
ATOM   9449  N  N    . GLU   B 1 296 ? 34.241  8.612   28.018  1.00 45.74  ?  295 GLU   A N    1 
ATOM   9450  C  CA   . GLU   B 1 296 ? 34.873  7.380   27.613  1.00 45.04  ?  295 GLU   A CA   1 
ATOM   9451  C  C    . GLU   B 1 296 ? 36.057  7.109   28.530  1.00 49.30  ?  295 GLU   A C    1 
ATOM   9452  O  O    . GLU   B 1 296 ? 36.469  7.953   29.341  1.00 41.13  ?  295 GLU   A O    1 
ATOM   9453  C  CB   . GLU   B 1 296 ? 35.339  7.432   26.147  1.00 44.67  ?  295 GLU   A CB   1 
ATOM   9454  C  CG   . GLU   B 1 296 ? 34.459  8.242   25.207  1.00 57.52  ?  295 GLU   A CG   1 
ATOM   9455  C  CD   . GLU   B 1 296 ? 33.212  7.482   24.727  1.00 61.55  ?  295 GLU   A CD   1 
ATOM   9456  O  OE1  . GLU   B 1 296 ? 33.080  6.277   25.015  1.00 66.27  ?  295 GLU   A OE1  1 
ATOM   9457  O  OE2  . GLU   B 1 296 ? 32.360  8.098   24.044  1.00 66.56  ?  295 GLU   A OE2  1 
ATOM   9458  H  H    . GLU   B 1 296 ? 34.778  9.283   28.040  1.00 54.89  ?  295 GLU   A H    1 
ATOM   9459  H  HA   . GLU   B 1 296 ? 34.238  6.652   27.698  1.00 54.05  ?  295 GLU   A HA   1 
ATOM   9460  H  HB2  . GLU   B 1 296 ? 36.225  7.825   26.123  1.00 53.61  ?  295 GLU   A HB2  1 
ATOM   9461  H  HB3  . GLU   B 1 296 ? 35.368  6.525   25.804  1.00 53.61  ?  295 GLU   A HB3  1 
ATOM   9462  H  HG2  . GLU   B 1 296 ? 34.161  9.042   25.669  1.00 69.02  ?  295 GLU   A HG2  1 
ATOM   9463  H  HG3  . GLU   B 1 296 ? 34.978  8.486   24.424  1.00 69.02  ?  295 GLU   A HG3  1 
ATOM   9464  N  N    . TYR   B 1 297 ? 36.633  5.922   28.352  1.00 40.22  ?  296 TYR   A N    1 
ATOM   9465  C  CA   . TYR   B 1 297 ? 37.734  5.464   29.177  1.00 45.61  ?  296 TYR   A CA   1 
ATOM   9466  C  C    . TYR   B 1 297 ? 38.408  4.340   28.403  1.00 47.42  ?  296 TYR   A C    1 
ATOM   9467  O  O    . TYR   B 1 297 ? 37.730  3.421   27.915  1.00 48.70  ?  296 TYR   A O    1 
ATOM   9468  C  CB   . TYR   B 1 297 ? 37.269  4.997   30.563  1.00 43.79  ?  296 TYR   A CB   1 
ATOM   9469  C  CG   . TYR   B 1 297 ? 38.422  4.448   31.318  1.00 43.39  ?  296 TYR   A CG   1 
ATOM   9470  C  CD1  . TYR   B 1 297 ? 38.855  3.144   31.080  1.00 47.79  ?  296 TYR   A CD1  1 
ATOM   9471  C  CD2  . TYR   B 1 297 ? 39.149  5.234   32.207  1.00 41.34  ?  296 TYR   A CD2  1 
ATOM   9472  C  CE1  . TYR   B 1 297 ? 39.989  2.607   31.752  1.00 41.38  ?  296 TYR   A CE1  1 
ATOM   9473  C  CE2  . TYR   B 1 297 ? 40.301  4.713   32.876  1.00 42.23  ?  296 TYR   A CE2  1 
ATOM   9474  C  CZ   . TYR   B 1 297 ? 40.700  3.392   32.630  1.00 39.46  ?  296 TYR   A CZ   1 
ATOM   9475  O  OH   . TYR   B 1 297 ? 41.796  2.825   33.259  1.00 50.07  ?  296 TYR   A OH   1 
ATOM   9476  H  H    . TYR   B 1 297 ? 36.396  5.358   27.749  1.00 48.27  ?  296 TYR   A H    1 
ATOM   9477  H  HA   . TYR   B 1 297 ? 38.367  6.182   29.335  1.00 54.73  ?  296 TYR   A HA   1 
ATOM   9478  H  HB2  . TYR   B 1 297 ? 36.901  5.747   31.056  1.00 52.55  ?  296 TYR   A HB2  1 
ATOM   9479  H  HB3  . TYR   B 1 297 ? 36.599  4.302   30.467  1.00 52.55  ?  296 TYR   A HB3  1 
ATOM   9480  H  HD1  . TYR   B 1 297 ? 38.393  2.615   30.470  1.00 57.34  ?  296 TYR   A HD1  1 
ATOM   9481  H  HD2  . TYR   B 1 297 ? 38.882  6.110   32.369  1.00 49.61  ?  296 TYR   A HD2  1 
ATOM   9482  H  HE1  . TYR   B 1 297 ? 40.249  1.728   31.597  1.00 49.65  ?  296 TYR   A HE1  1 
ATOM   9483  H  HE2  . TYR   B 1 297 ? 40.781  5.246   33.468  1.00 50.67  ?  296 TYR   A HE2  1 
ATOM   9484  H  HH   . TYR   B 1 297 ? 42.125  3.368   33.808  1.00 60.09  ?  296 TYR   A HH   1 
ATOM   9485  N  N    . LYS   B 1 298 ? 39.721  4.466   28.229  1.00 42.61  ?  297 LYS   A N    1 
ATOM   9486  C  CA   . LYS   B 1 298 ? 40.596  3.424   27.703  1.00 43.33  ?  297 LYS   A CA   1 
ATOM   9487  C  C    . LYS   B 1 298 ? 41.718  3.385   28.721  1.00 39.88  ?  297 LYS   A C    1 
ATOM   9488  O  O    . LYS   B 1 298 ? 42.261  4.440   29.060  1.00 48.42  ?  297 LYS   A O    1 
ATOM   9489  C  CB   . LYS   B 1 298 ? 41.141  3.729   26.307  1.00 44.07  ?  297 LYS   A CB   1 
ATOM   9490  C  CG   . LYS   B 1 298 ? 40.119  3.666   25.156  1.00 45.75  ?  297 LYS   A CG   1 
ATOM   9491  C  CD   . LYS   B 1 298 ? 40.789  3.710   23.770  1.00 51.45  ?  297 LYS   A CD   1 
ATOM   9492  C  CE   . LYS   B 1 298 ? 40.230  2.612   22.857  1.00 66.84  ?  297 LYS   A CE   1 
ATOM   9493  N  NZ   . LYS   B 1 298 ? 40.097  2.994   21.401  1.00 81.44  ?  297 LYS   A NZ   1 
ATOM   9494  H  H    . LYS   B 1 298 ? 40.151  5.186   28.418  1.00 51.14  ?  297 LYS   A H    1 
ATOM   9495  H  HA   . LYS   B 1 298 ? 40.140  2.573   27.606  1.00 52.00  ?  297 LYS   A HA   1 
ATOM   9496  H  HB2  . LYS   B 1 298 ? 41.509  4.626   26.315  1.00 52.89  ?  297 LYS   A HB2  1 
ATOM   9497  H  HB3  . LYS   B 1 298 ? 41.839  3.086   26.107  1.00 52.89  ?  297 LYS   A HB3  1 
ATOM   9498  H  HG2  . LYS   B 1 298 ? 39.618  2.838   25.222  1.00 54.90  ?  297 LYS   A HG2  1 
ATOM   9499  H  HG3  . LYS   B 1 298 ? 39.518  4.424   25.224  1.00 54.90  ?  297 LYS   A HG3  1 
ATOM   9500  H  HD2  . LYS   B 1 298 ? 40.619  4.570   23.356  1.00 61.73  ?  297 LYS   A HD2  1 
ATOM   9501  H  HD3  . LYS   B 1 298 ? 41.744  3.571   23.868  1.00 61.73  ?  297 LYS   A HD3  1 
ATOM   9502  H  HE2  . LYS   B 1 298 ? 40.822  1.844   22.902  1.00 80.20  ?  297 LYS   A HE2  1 
ATOM   9503  H  HE3  . LYS   B 1 298 ? 39.347  2.368   23.175  1.00 80.20  ?  297 LYS   A HE3  1 
ATOM   9504  H  HZ1  . LYS   B 1 298 ? 39.771  2.309   20.935  1.00 97.73  ?  297 LYS   A HZ1  1 
ATOM   9505  H  HZ2  . LYS   B 1 298 ? 39.545  3.688   21.318  1.00 97.73  ?  297 LYS   A HZ2  1 
ATOM   9506  H  HZ3  . LYS   B 1 298 ? 40.892  3.216   21.070  1.00 97.73  ?  297 LYS   A HZ3  1 
ATOM   9507  N  N    . GLY   B 1 299 ? 42.053  2.207   29.233  1.00 34.77  ?  298 GLY   A N    1 
ATOM   9508  C  CA   . GLY   B 1 299 ? 43.048  2.124   30.273  1.00 32.18  ?  298 GLY   A CA   1 
ATOM   9509  C  C    . GLY   B 1 299 ? 43.346  0.708   30.678  1.00 31.85  ?  298 GLY   A C    1 
ATOM   9510  O  O    . GLY   B 1 299 ? 42.658  -0.244  30.258  1.00 28.51  ?  298 GLY   A O    1 
ATOM   9511  H  H    . GLY   B 1 299 ? 41.717  1.453   28.992  1.00 41.73  ?  298 GLY   A H    1 
ATOM   9512  H  HA2  . GLY   B 1 299 ? 43.872  2.531   29.961  1.00 38.61  ?  298 GLY   A HA2  1 
ATOM   9513  H  HA3  . GLY   B 1 299 ? 42.735  2.605   31.055  1.00 38.61  ?  298 GLY   A HA3  1 
ATOM   9514  N  N    . PRO   B 1 300 ? 44.475  0.528   31.457  1.00 37.51  ?  299 PRO   A N    1 
ATOM   9515  C  CA   . PRO   B 1 300 ? 44.864  -0.823  31.910  1.00 29.51  ?  299 PRO   A CA   1 
ATOM   9516  C  C    . PRO   B 1 300 ? 43.951  -1.316  33.020  1.00 31.90  ?  299 PRO   A C    1 
ATOM   9517  O  O    . PRO   B 1 300 ? 44.036  -0.832  34.162  1.00 35.05  ?  299 PRO   A O    1 
ATOM   9518  C  CB   . PRO   B 1 300 ? 46.280  -0.634  32.434  1.00 30.79  ?  299 PRO   A CB   1 
ATOM   9519  C  CG   . PRO   B 1 300 ? 46.310  0.782   32.845  1.00 27.91  ?  299 PRO   A CG   1 
ATOM   9520  C  CD   . PRO   B 1 300 ? 45.505  1.531   31.806  1.00 23.71  ?  299 PRO   A CD   1 
ATOM   9521  H  HA   . PRO   B 1 300 ? 44.873  -1.444  31.165  1.00 35.41  ?  299 PRO   A HA   1 
ATOM   9522  H  HB2  . PRO   B 1 300 ? 46.441  -1.223  33.187  1.00 36.95  ?  299 PRO   A HB2  1 
ATOM   9523  H  HB3  . PRO   B 1 300 ? 46.924  -0.810  31.731  1.00 36.95  ?  299 PRO   A HB3  1 
ATOM   9524  H  HG2  . PRO   B 1 300 ? 45.910  0.877   33.723  1.00 33.50  ?  299 PRO   A HG2  1 
ATOM   9525  H  HG3  . PRO   B 1 300 ? 47.227  1.099   32.862  1.00 33.50  ?  299 PRO   A HG3  1 
ATOM   9526  H  HD2  . PRO   B 1 300 ? 45.105  2.332   32.179  1.00 28.45  ?  299 PRO   A HD2  1 
ATOM   9527  H  HD3  . PRO   B 1 300 ? 46.049  1.760   31.036  1.00 28.45  ?  299 PRO   A HD3  1 
ATOM   9528  N  N    . ILE   B 1 301 ? 43.107  -2.291  32.717  1.00 27.16  ?  300 ILE   A N    1 
ATOM   9529  C  CA   . ILE   B 1 301 ? 42.051  -2.745  33.610  1.00 28.43  ?  300 ILE   A CA   1 
ATOM   9530  C  C    . ILE   B 1 301 ? 42.401  -4.167  33.998  1.00 31.73  ?  300 ILE   A C    1 
ATOM   9531  O  O    . ILE   B 1 301 ? 42.928  -4.923  33.174  1.00 30.15  ?  300 ILE   A O    1 
ATOM   9532  C  CB   . ILE   B 1 301 ? 40.678  -2.674  32.923  1.00 27.52  ?  300 ILE   A CB   1 
ATOM   9533  C  CG1  . ILE   B 1 301 ? 40.383  -1.223  32.585  1.00 26.80  ?  300 ILE   A CG1  1 
ATOM   9534  C  CG2  . ILE   B 1 301 ? 39.576  -3.252  33.805  1.00 34.05  ?  300 ILE   A CG2  1 
ATOM   9535  C  CD1  . ILE   B 1 301 ? 40.252  -0.333  33.757  1.00 33.21  ?  300 ILE   A CD1  1 
ATOM   9536  H  H    . ILE   B 1 301 ? 43.127  -2.721  31.973  1.00 32.59  ?  300 ILE   A H    1 
ATOM   9537  H  HA   . ILE   B 1 301 ? 42.006  -2.196  34.409  1.00 34.12  ?  300 ILE   A HA   1 
ATOM   9538  H  HB   . ILE   B 1 301 ? 40.704  -3.210  32.115  1.00 33.02  ?  300 ILE   A HB   1 
ATOM   9539  H  HG12 . ILE   B 1 301 ? 41.107  -0.881  32.037  1.00 32.16  ?  300 ILE   A HG12 1 
ATOM   9540  H  HG13 . ILE   B 1 301 ? 39.548  -1.184  32.093  1.00 32.16  ?  300 ILE   A HG13 1 
ATOM   9541  H  HG21 . ILE   B 1 301 ? 38.717  -3.090  33.384  1.00 40.86  ?  300 ILE   A HG21 1 
ATOM   9542  H  HG22 . ILE   B 1 301 ? 39.720  -4.206  33.906  1.00 40.86  ?  300 ILE   A HG22 1 
ATOM   9543  H  HG23 . ILE   B 1 301 ? 39.606  -2.819  34.672  1.00 40.86  ?  300 ILE   A HG23 1 
ATOM   9544  H  HD11 . ILE   B 1 301 ? 39.973  0.546   33.457  1.00 39.85  ?  300 ILE   A HD11 1 
ATOM   9545  H  HD12 . ILE   B 1 301 ? 39.589  -0.701  34.361  1.00 39.85  ?  300 ILE   A HD12 1 
ATOM   9546  H  HD13 . ILE   B 1 301 ? 41.110  -0.272  34.206  1.00 39.85  ?  300 ILE   A HD13 1 
ATOM   9547  N  N    . THR   B 1 302 ? 42.120  -4.527  35.248  1.00 30.51  ?  301 THR   A N    1 
ATOM   9548  C  CA   . THR   B 1 302 ? 42.434  -5.857  35.717  1.00 32.22  ?  301 THR   A CA   1 
ATOM   9549  C  C    . THR   B 1 302 ? 41.290  -6.497  36.457  1.00 24.10  ?  301 THR   A C    1 
ATOM   9550  O  O    . THR   B 1 302 ? 41.286  -7.728  36.559  1.00 22.00  ?  301 THR   A O    1 
ATOM   9551  C  CB   . THR   B 1 302 ? 43.714  -5.839  36.589  1.00 30.13  ?  301 THR   A CB   1 
ATOM   9552  O  OG1  . THR   B 1 302 ? 44.175  -7.181  36.860  1.00 26.68  ?  301 THR   A OG1  1 
ATOM   9553  C  CG2  . THR   B 1 302 ? 43.479  -5.127  37.929  1.00 25.91  ?  301 THR   A CG2  1 
ATOM   9554  H  H    . THR   B 1 302 ? 41.750  -4.016  35.834  1.00 36.61  ?  301 THR   A H    1 
ATOM   9555  H  HA   . THR   B 1 302 ? 42.643  -6.434  34.966  1.00 38.67  ?  301 THR   A HA   1 
ATOM   9556  H  HB   . THR   B 1 302 ? 44.394  -5.356  36.096  1.00 36.16  ?  301 THR   A HB   1 
ATOM   9557  H  HG1  . THR   B 1 302 ? 44.335  -7.581  36.139  1.00 32.02  ?  301 THR   A HG1  1 
ATOM   9558  H  HG21 . THR   B 1 302 ? 43.971  -5.576  38.634  1.00 31.09  ?  301 THR   A HG21 1 
ATOM   9559  H  HG22 . THR   B 1 302 ? 43.779  -4.206  37.873  1.00 31.09  ?  301 THR   A HG22 1 
ATOM   9560  H  HG23 . THR   B 1 302 ? 42.534  -5.137  38.150  1.00 31.09  ?  301 THR   A HG23 1 
ATOM   9561  N  N    . ASP   B 1 303 ? 40.294  -5.731  36.935  1.00 30.69  ?  302 ASP   A N    1 
ATOM   9562  C  CA   . ASP   B 1 303 ? 39.038  -6.352  37.354  1.00 28.61  ?  302 ASP   A CA   1 
ATOM   9563  C  C    . ASP   B 1 303 ? 37.838  -5.534  36.893  1.00 29.66  ?  302 ASP   A C    1 
ATOM   9564  O  O    . ASP   B 1 303 ? 37.872  -4.302  36.894  1.00 27.68  ?  302 ASP   A O    1 
ATOM   9565  C  CB   . ASP   B 1 303 ? 38.860  -6.470  38.886  1.00 31.12  ?  302 ASP   A CB   1 
ATOM   9566  C  CG   . ASP   B 1 303 ? 40.130  -6.846  39.630  1.00 31.55  ?  302 ASP   A CG   1 
ATOM   9567  O  OD1  . ASP   B 1 303 ? 40.536  -8.025  39.487  1.00 35.43  ?  302 ASP   A OD1  1 
ATOM   9568  O  OD2  . ASP   B 1 303 ? 40.688  -6.003  40.391  1.00 30.61  ?  302 ASP   A OD2  1 
ATOM   9569  H  H    . ASP   B 1 303 ? 40.327  -4.876  37.022  1.00 36.83  ?  302 ASP   A H    1 
ATOM   9570  H  HA   . ASP   B 1 303 ? 39.054  -7.231  36.944  1.00 34.34  ?  302 ASP   A HA   1 
ATOM   9571  H  HB2  . ASP   B 1 303 ? 38.559  -5.616  39.231  1.00 37.34  ?  302 ASP   A HB2  1 
ATOM   9572  H  HB3  . ASP   B 1 303 ? 38.198  -7.155  39.070  1.00 37.34  ?  302 ASP   A HB3  1 
ATOM   9573  N  N    . VAL   B 1 304 ? 36.737  -6.220  36.587  1.00 30.90  ?  303 VAL   A N    1 
ATOM   9574  C  CA   . VAL   B 1 304 ? 35.477  -5.554  36.263  1.00 26.36  ?  303 VAL   A CA   1 
ATOM   9575  C  C    . VAL   B 1 304 ? 34.325  -6.235  36.986  1.00 25.07  ?  303 VAL   A C    1 
ATOM   9576  O  O    . VAL   B 1 304 ? 34.188  -7.458  36.942  1.00 25.97  ?  303 VAL   A O    1 
ATOM   9577  C  CB   . VAL   B 1 304 ? 35.185  -5.529  34.746  1.00 28.30  ?  303 VAL   A CB   1 
ATOM   9578  C  CG1  . VAL   B 1 304 ? 33.843  -4.809  34.449  1.00 26.43  ?  303 VAL   A CG1  1 
ATOM   9579  C  CG2  . VAL   B 1 304 ? 36.306  -4.855  34.007  1.00 32.15  ?  303 VAL   A CG2  1 
ATOM   9580  H  H    . VAL   B 1 304 ? 36.695  -7.079  36.561  1.00 37.08  ?  303 VAL   A H    1 
ATOM   9581  H  HA   . VAL   B 1 304 ? 35.545  -4.642  36.587  1.00 31.64  ?  303 VAL   A HA   1 
ATOM   9582  H  HB   . VAL   B 1 304 ? 35.112  -6.445  34.434  1.00 33.95  ?  303 VAL   A HB   1 
ATOM   9583  H  HG11 . VAL   B 1 304 ? 33.695  -4.801  33.490  1.00 31.71  ?  303 VAL   A HG11 1 
ATOM   9584  H  HG12 . VAL   B 1 304 ? 33.124  -5.286  34.891  1.00 31.71  ?  303 VAL   A HG12 1 
ATOM   9585  H  HG13 . VAL   B 1 304 ? 33.892  -3.899  34.783  1.00 31.71  ?  303 VAL   A HG13 1 
ATOM   9586  H  HG21 . VAL   B 1 304 ? 36.109  -4.866  33.058  1.00 38.58  ?  303 VAL   A HG21 1 
ATOM   9587  H  HG22 . VAL   B 1 304 ? 36.384  -3.940  34.319  1.00 38.58  ?  303 VAL   A HG22 1 
ATOM   9588  H  HG23 . VAL   B 1 304 ? 37.131  -5.335  34.180  1.00 38.58  ?  303 VAL   A HG23 1 
ATOM   9589  N  N    . PHE   B 1 305 ? 33.478  -5.435  37.621  1.00 28.64  ?  304 PHE   A N    1 
ATOM   9590  C  CA   . PHE   B 1 305 ? 32.294  -5.902  38.346  1.00 26.14  ?  304 PHE   A CA   1 
ATOM   9591  C  C    . PHE   B 1 305 ? 31.004  -5.575  37.597  1.00 29.56  ?  304 PHE   A C    1 
ATOM   9592  O  O    . PHE   B 1 305 ? 30.744  -4.413  37.262  1.00 29.49  ?  304 PHE   A O    1 
ATOM   9593  C  CB   . PHE   B 1 305 ? 32.207  -5.260  39.728  1.00 30.00  ?  304 PHE   A CB   1 
ATOM   9594  C  CG   . PHE   B 1 305 ? 33.285  -5.700  40.623  1.00 30.67  ?  304 PHE   A CG   1 
ATOM   9595  C  CD1  . PHE   B 1 305 ? 33.038  -6.617  41.593  1.00 29.24  ?  304 PHE   A CD1  1 
ATOM   9596  C  CD2  . PHE   B 1 305 ? 34.564  -5.223  40.481  1.00 31.42  ?  304 PHE   A CD2  1 
ATOM   9597  C  CE1  . PHE   B 1 305 ? 34.035  -7.077  42.376  1.00 35.58  ?  304 PHE   A CE1  1 
ATOM   9598  C  CE2  . PHE   B 1 305 ? 35.553  -5.661  41.328  1.00 36.87  ?  304 PHE   A CE2  1 
ATOM   9599  C  CZ   . PHE   B 1 305 ? 35.282  -6.598  42.243  1.00 35.46  ?  304 PHE   A CZ   1 
ATOM   9600  H  H    . PHE   B 1 305 ? 33.568  -4.580  37.649  1.00 34.36  ?  304 PHE   A H    1 
ATOM   9601  H  HA   . PHE   B 1 305 ? 32.369  -6.867  38.420  1.00 31.36  ?  304 PHE   A HA   1 
ATOM   9602  H  HB2  . PHE   B 1 305 ? 32.269  -4.297  39.633  1.00 36.00  ?  304 PHE   A HB2  1 
ATOM   9603  H  HB3  . PHE   B 1 305 ? 31.360  -5.500  40.136  1.00 36.00  ?  304 PHE   A HB3  1 
ATOM   9604  H  HD1  . PHE   B 1 305 ? 32.171  -6.930  41.719  1.00 35.09  ?  304 PHE   A HD1  1 
ATOM   9605  H  HD2  . PHE   B 1 305 ? 34.760  -4.606  39.813  1.00 37.71  ?  304 PHE   A HD2  1 
ATOM   9606  H  HE1  . PHE   B 1 305 ? 33.857  -7.732  43.013  1.00 42.70  ?  304 PHE   A HE1  1 
ATOM   9607  H  HE2  . PHE   B 1 305 ? 36.410  -5.306  41.265  1.00 44.24  ?  304 PHE   A HE2  1 
ATOM   9608  H  HZ   . PHE   B 1 305 ? 35.961  -6.919  42.791  1.00 42.56  ?  304 PHE   A HZ   1 
ATOM   9609  N  N    . TYR   B 1 306 ? 30.176  -6.590  37.390  1.00 26.58  ?  305 TYR   A N    1 
ATOM   9610  C  CA   . TYR   B 1 306 ? 28.859  -6.418  36.795  1.00 27.66  ?  305 TYR   A CA   1 
ATOM   9611  C  C    . TYR   B 1 306 ? 27.810  -6.915  37.790  1.00 29.78  ?  305 TYR   A C    1 
ATOM   9612  O  O    . TYR   B 1 306 ? 27.947  -8.004  38.362  1.00 28.15  ?  305 TYR   A O    1 
ATOM   9613  C  CB   . TYR   B 1 306 ? 28.725  -7.176  35.470  1.00 23.00  ?  305 TYR   A CB   1 
ATOM   9614  C  CG   . TYR   B 1 306 ? 29.885  -7.024  34.513  1.00 34.66  ?  305 TYR   A CG   1 
ATOM   9615  C  CD1  . TYR   B 1 306 ? 29.746  -6.269  33.355  1.00 29.53  ?  305 TYR   A CD1  1 
ATOM   9616  C  CD2  . TYR   B 1 306 ? 31.108  -7.665  34.741  1.00 28.32  ?  305 TYR   A CD2  1 
ATOM   9617  C  CE1  . TYR   B 1 306 ? 30.765  -6.123  32.477  1.00 30.71  ?  305 TYR   A CE1  1 
ATOM   9618  C  CE2  . TYR   B 1 306 ? 32.176  -7.530  33.832  1.00 30.82  ?  305 TYR   A CE2  1 
ATOM   9619  C  CZ   . TYR   B 1 306 ? 31.975  -6.768  32.722  1.00 32.62  ?  305 TYR   A CZ   1 
ATOM   9620  O  OH   . TYR   B 1 306 ? 32.954  -6.641  31.836  1.00 30.81  ?  305 TYR   A OH   1 
ATOM   9621  H  H    . TYR   B 1 306 ? 30.360  -7.405  37.591  1.00 31.89  ?  305 TYR   A H    1 
ATOM   9622  H  HA   . TYR   B 1 306 ? 28.708  -5.478  36.612  1.00 33.19  ?  305 TYR   A HA   1 
ATOM   9623  H  HB2  . TYR   B 1 306 ? 28.635  -8.121  35.667  1.00 27.60  ?  305 TYR   A HB2  1 
ATOM   9624  H  HB3  . TYR   B 1 306 ? 27.931  -6.855  35.014  1.00 27.60  ?  305 TYR   A HB3  1 
ATOM   9625  H  HD1  . TYR   B 1 306 ? 28.933  -5.853  33.180  1.00 35.44  ?  305 TYR   A HD1  1 
ATOM   9626  H  HD2  . TYR   B 1 306 ? 31.217  -8.187  35.503  1.00 33.98  ?  305 TYR   A HD2  1 
ATOM   9627  H  HE1  . TYR   B 1 306 ? 30.658  -5.596  31.718  1.00 36.85  ?  305 TYR   A HE1  1 
ATOM   9628  H  HE2  . TYR   B 1 306 ? 32.993  -7.948  33.986  1.00 36.99  ?  305 TYR   A HE2  1 
ATOM   9629  H  HH   . TYR   B 1 306 ? 33.403  -7.350  31.800  1.00 36.97  ?  305 TYR   A HH   1 
ATOM   9630  N  N    . LYS   B 1 307 ? 26.759  -6.119  37.986  1.00 31.46  ?  306 LYS   A N    1 
ATOM   9631  C  CA   . LYS   B 1 307 ? 25.589  -6.576  38.732  1.00 29.48  ?  306 LYS   A CA   1 
ATOM   9632  C  C    . LYS   B 1 307 ? 24.857  -7.658  37.936  1.00 28.17  ?  306 LYS   A C    1 
ATOM   9633  O  O    . LYS   B 1 307 ? 24.928  -7.708  36.717  1.00 31.40  ?  306 LYS   A O    1 
ATOM   9634  C  CB   . LYS   B 1 307 ? 24.655  -5.411  39.034  1.00 32.84  ?  306 LYS   A CB   1 
ATOM   9635  C  CG   . LYS   B 1 307 ? 25.068  -4.568  40.253  1.00 34.42  ?  306 LYS   A CG   1 
ATOM   9636  C  CD   . LYS   B 1 307 ? 24.255  -3.265  40.283  1.00 31.70  ?  306 LYS   A CD   1 
ATOM   9637  C  CE   . LYS   B 1 307 ? 24.815  -2.245  41.265  1.00 44.49  ?  306 LYS   A CE   1 
ATOM   9638  N  NZ   . LYS   B 1 307 ? 24.549  -2.618  42.690  1.00 43.70  ?  306 LYS   A NZ   1 
ATOM   9639  H  H    . LYS   B 1 307 ? 26.699  -5.312  37.697  1.00 37.75  ?  306 LYS   A H    1 
ATOM   9640  H  HA   . LYS   B 1 307 ? 25.864  -6.951  39.583  1.00 35.38  ?  306 LYS   A HA   1 
ATOM   9641  H  HB2  . LYS   B 1 307 ? 24.634  -4.823  38.263  1.00 39.41  ?  306 LYS   A HB2  1 
ATOM   9642  H  HB3  . LYS   B 1 307 ? 23.767  -5.762  39.207  1.00 39.41  ?  306 LYS   A HB3  1 
ATOM   9643  H  HG2  . LYS   B 1 307 ? 24.894  -5.063  41.068  1.00 41.31  ?  306 LYS   A HG2  1 
ATOM   9644  H  HG3  . LYS   B 1 307 ? 26.011  -4.346  40.193  1.00 41.31  ?  306 LYS   A HG3  1 
ATOM   9645  H  HD2  . LYS   B 1 307 ? 24.264  -2.865  39.399  1.00 38.04  ?  306 LYS   A HD2  1 
ATOM   9646  H  HD3  . LYS   B 1 307 ? 23.344  -3.466  40.546  1.00 38.04  ?  306 LYS   A HD3  1 
ATOM   9647  H  HE2  . LYS   B 1 307 ? 25.775  -2.182  41.144  1.00 53.39  ?  306 LYS   A HE2  1 
ATOM   9648  H  HE3  . LYS   B 1 307 ? 24.402  -1.383  41.097  1.00 53.39  ?  306 LYS   A HE3  1 
ATOM   9649  H  HZ1  . LYS   B 1 307 ? 24.600  -1.896  43.209  1.00 52.45  ?  306 LYS   A HZ1  1 
ATOM   9650  H  HZ2  . LYS   B 1 307 ? 23.735  -2.971  42.766  1.00 52.45  ?  306 LYS   A HZ2  1 
ATOM   9651  H  HZ3  . LYS   B 1 307 ? 25.149  -3.215  42.966  1.00 52.45  ?  306 LYS   A HZ3  1 
ATOM   9652  N  N    . GLU   B 1 308 ? 24.223  -8.565  38.654  1.00 26.53  ?  307 GLU   A N    1 
ATOM   9653  C  CA   . GLU   B 1 308 ? 23.495  -9.703  38.117  1.00 31.00  ?  307 GLU   A CA   1 
ATOM   9654  C  C    . GLU   B 1 308 ? 22.312  -9.997  39.049  1.00 34.82  ?  307 GLU   A C    1 
ATOM   9655  O  O    . GLU   B 1 308 ? 22.185  -9.415  40.140  1.00 29.44  ?  307 GLU   A O    1 
ATOM   9656  C  CB   . GLU   B 1 308 ? 24.431  -10.901 37.995  1.00 31.01  ?  307 GLU   A CB   1 
ATOM   9657  C  CG   . GLU   B 1 308 ? 23.885  -12.126 37.325  1.00 34.57  ?  307 GLU   A CG   1 
ATOM   9658  C  CD   . GLU   B 1 308 ? 23.267  -11.820 35.987  1.00 37.06  ?  307 GLU   A CD   1 
ATOM   9659  O  OE1  . GLU   B 1 308 ? 22.017  -11.614 35.957  1.00 39.69  ?  307 GLU   A OE1  1 
ATOM   9660  O  OE2  . GLU   B 1 308 ? 24.021  -11.789 34.954  1.00 30.54  ?  307 GLU   A OE2  1 
ATOM   9661  H  H    . GLU   B 1 308 ? 24.195  -8.545  39.513  1.00 31.84  ?  307 GLU   A H    1 
ATOM   9662  H  HA   . GLU   B 1 308 ? 23.133  -9.503  37.239  1.00 37.20  ?  307 GLU   A HA   1 
ATOM   9663  H  HB2  . GLU   B 1 308 ? 25.208  -10.623 37.485  1.00 37.22  ?  307 GLU   A HB2  1 
ATOM   9664  H  HB3  . GLU   B 1 308 ? 24.698  -11.165 38.889  1.00 37.22  ?  307 GLU   A HB3  1 
ATOM   9665  H  HG2  . GLU   B 1 308 ? 24.605  -12.761 37.186  1.00 41.48  ?  307 GLU   A HG2  1 
ATOM   9666  H  HG3  . GLU   B 1 308 ? 23.201  -12.519 37.890  1.00 41.48  ?  307 GLU   A HG3  1 
ATOM   9667  N  N    . ASN   B 1 309 ? 21.442  -10.903 38.598  1.00 27.41  ?  308 ASN   A N    1 
ATOM   9668  C  CA   . ASN   B 1 309 ? 20.477  -11.547 39.466  1.00 29.56  ?  308 ASN   A CA   1 
ATOM   9669  C  C    . ASN   B 1 309 ? 20.353  -12.994 39.025  1.00 35.37  ?  308 ASN   A C    1 
ATOM   9670  O  O    . ASN   B 1 309 ? 20.800  -13.910 39.744  1.00 28.59  ?  308 ASN   A O    1 
ATOM   9671  C  CB   . ASN   B 1 309 ? 19.114  -10.867 39.394  1.00 29.33  ?  308 ASN   A CB   1 
ATOM   9672  C  CG   . ASN   B 1 309 ? 18.174  -11.323 40.541  1.00 35.35  ?  308 ASN   A CG   1 
ATOM   9673  O  OD1  . ASN   B 1 309 ? 17.647  -12.410 40.516  1.00 34.76  ?  308 ASN   A OD1  1 
ATOM   9674  N  ND2  . ASN   B 1 309 ? 18.022  -10.500 41.547  1.00 35.81  ?  308 ASN   A ND2  1 
ATOM   9675  N  N    . SER   B 1 310 ? 19.755  -13.198 37.829  1.00 26.28  ?  309 SER   A N    1 
ATOM   9676  C  CA   . SER   B 1 310 ? 19.607  -14.537 37.242  1.00 27.36  ?  309 SER   A CA   1 
ATOM   9677  C  C    . SER   B 1 310 ? 19.829  -14.461 35.746  1.00 33.58  ?  309 SER   A C    1 
ATOM   9678  O  O    . SER   B 1 310 ? 19.103  -13.740 35.056  1.00 31.18  ?  309 SER   A O    1 
ATOM   9679  C  CB   . SER   B 1 310 ? 18.215  -15.137 37.563  1.00 37.02  ?  309 SER   A CB   1 
ATOM   9680  O  OG   . SER   B 1 310 ? 18.038  -16.477 37.099  1.00 37.53  ?  309 SER   A OG   1 
ATOM   9681  H  H    . SER   B 1 310 ? 19.428  -12.570 37.342  1.00 31.54  ?  309 SER   A H    1 
ATOM   9682  H  HA   . SER   B 1 310 ? 20.289  -15.120 37.611  1.00 32.83  ?  309 SER   A HA   1 
ATOM   9683  H  HB2  . SER   B 1 310 ? 18.098  -15.132 38.525  1.00 44.42  ?  309 SER   A HB2  1 
ATOM   9684  H  HB3  . SER   B 1 310 ? 17.541  -14.580 37.143  1.00 44.42  ?  309 SER   A HB3  1 
ATOM   9685  H  HG   . SER   B 1 310 ? 18.722  -16.933 37.269  1.00 45.04  ?  309 SER   A HG   1 
ATOM   9686  N  N    . TYR   B 1 311 ? 20.845  -15.179 35.249  1.00 34.16  ?  310 TYR   A N    1 
ATOM   9687  C  CA   . TYR   B 1 311 ? 21.121  -15.250 33.823  1.00 27.79  ?  310 TYR   A CA   1 
ATOM   9688  C  C    . TYR   B 1 311 ? 20.935  -16.673 33.341  1.00 35.57  ?  310 TYR   A C    1 
ATOM   9689  O  O    . TYR   B 1 311 ? 21.422  -17.607 33.996  1.00 32.30  ?  310 TYR   A O    1 
ATOM   9690  C  CB   . TYR   B 1 311 ? 22.543  -14.833 33.491  1.00 39.99  ?  310 TYR   A CB   1 
ATOM   9691  C  CG   . TYR   B 1 311 ? 22.946  -15.099 32.050  1.00 37.18  ?  310 TYR   A CG   1 
ATOM   9692  C  CD1  . TYR   B 1 311 ? 22.535  -14.253 31.042  1.00 32.34  ?  310 TYR   A CD1  1 
ATOM   9693  C  CD2  . TYR   B 1 311 ? 23.744  -16.169 31.714  1.00 29.83  ?  310 TYR   A CD2  1 
ATOM   9694  C  CE1  . TYR   B 1 311 ? 22.918  -14.445 29.756  1.00 33.66  ?  310 TYR   A CE1  1 
ATOM   9695  C  CE2  . TYR   B 1 311 ? 24.127  -16.375 30.420  1.00 31.57  ?  310 TYR   A CE2  1 
ATOM   9696  C  CZ   . TYR   B 1 311 ? 23.682  -15.515 29.436  1.00 36.02  ?  310 TYR   A CZ   1 
ATOM   9697  O  OH   . TYR   B 1 311 ? 24.030  -15.698 28.131  1.00 37.63  ?  310 TYR   A OH   1 
ATOM   9698  H  H    . TYR   B 1 311 ? 21.391  -15.636 35.732  1.00 40.99  ?  310 TYR   A H    1 
ATOM   9699  H  HA   . TYR   B 1 311 ? 20.498  -14.658 33.374  1.00 33.35  ?  310 TYR   A HA   1 
ATOM   9700  H  HB2  . TYR   B 1 311 ? 22.633  -13.880 33.651  1.00 47.99  ?  310 TYR   A HB2  1 
ATOM   9701  H  HB3  . TYR   B 1 311 ? 23.153  -15.324 34.063  1.00 47.99  ?  310 TYR   A HB3  1 
ATOM   9702  H  HD1  . TYR   B 1 311 ? 21.983  -13.534 31.249  1.00 38.81  ?  310 TYR   A HD1  1 
ATOM   9703  H  HD2  . TYR   B 1 311 ? 24.025  -16.759 32.376  1.00 35.80  ?  310 TYR   A HD2  1 
ATOM   9704  H  HE1  . TYR   B 1 311 ? 22.657  -13.844 29.096  1.00 40.40  ?  310 TYR   A HE1  1 
ATOM   9705  H  HE2  . TYR   B 1 311 ? 24.683  -17.088 30.203  1.00 37.89  ?  310 TYR   A HE2  1 
ATOM   9706  H  HH   . TYR   B 1 311 ? 23.712  -16.422 27.848  1.00 45.16  ?  310 TYR   A HH   1 
ATOM   9707  N  N    . THR   B 1 312 ? 20.244  -16.822 32.196  1.00 36.82  ?  311 THR   A N    1 
ATOM   9708  C  CA   . THR   B 1 312 ? 20.155  -18.090 31.480  1.00 37.48  ?  311 THR   A CA   1 
ATOM   9709  C  C    . THR   B 1 312 ? 20.465  -17.935 29.991  1.00 37.50  ?  311 THR   A C    1 
ATOM   9710  O  O    . THR   B 1 312 ? 19.803  -17.156 29.278  1.00 33.05  ?  311 THR   A O    1 
ATOM   9711  C  CB   . THR   B 1 312 ? 18.777  -18.728 31.649  1.00 32.67  ?  311 THR   A CB   1 
ATOM   9712  O  OG1  . THR   B 1 312 ? 18.477  -18.878 33.043  1.00 32.72  ?  311 THR   A OG1  1 
ATOM   9713  C  CG2  . THR   B 1 312 ? 18.816  -20.077 30.980  1.00 32.50  ?  311 THR   A CG2  1 
ATOM   9714  H  H    . THR   B 1 312 ? 19.812  -16.185 31.814  1.00 44.18  ?  311 THR   A H    1 
ATOM   9715  H  HA   . THR   B 1 312 ? 20.841  -18.667 31.851  1.00 44.97  ?  311 THR   A HA   1 
ATOM   9716  H  HB   . THR   B 1 312 ? 18.080  -18.181 31.254  1.00 39.20  ?  311 THR   A HB   1 
ATOM   9717  H  HG1  . THR   B 1 312 ? 19.162  -19.128 33.459  1.00 39.27  ?  311 THR   A HG1  1 
ATOM   9718  H  HG21 . THR   B 1 312 ? 18.180  -20.676 31.403  1.00 38.99  ?  311 THR   A HG21 1 
ATOM   9719  H  HG22 . THR   B 1 312 ? 18.588  -19.989 30.041  1.00 38.99  ?  311 THR   A HG22 1 
ATOM   9720  H  HG23 . THR   B 1 312 ? 19.704  -20.459 31.054  1.00 38.99  ?  311 THR   A HG23 1 
ATOM   9721  N  N    . THR   B 1 313 ? 21.459  -18.707 29.531  1.00 31.47  ?  312 THR   A N    1 
ATOM   9722  C  CA   . THR   B 1 313 ? 21.896  -18.636 28.148  1.00 31.94  ?  312 THR   A CA   1 
ATOM   9723  C  C    . THR   B 1 313 ? 20.755  -19.008 27.192  1.00 41.12  ?  312 THR   A C    1 
ATOM   9724  O  O    . THR   B 1 313 ? 19.823  -19.729 27.545  1.00 36.33  ?  312 THR   A O    1 
ATOM   9725  C  CB   . THR   B 1 313 ? 23.069  -19.586 27.883  1.00 34.52  ?  312 THR   A CB   1 
ATOM   9726  O  OG1  . THR   B 1 313 ? 23.650  -19.277 26.611  1.00 34.04  ?  312 THR   A OG1  1 
ATOM   9727  C  CG2  . THR   B 1 313 ? 22.630  -21.049 27.848  1.00 32.51  ?  312 THR   A CG2  1 
ATOM   9728  H  H    . THR   B 1 313 ? 21.892  -19.278 30.007  1.00 37.77  ?  312 THR   A H    1 
ATOM   9729  H  HA   . THR   B 1 313 ? 22.182  -17.725 27.974  1.00 38.33  ?  312 THR   A HA   1 
ATOM   9730  H  HB   . THR   B 1 313 ? 23.712  -19.477 28.601  1.00 41.42  ?  312 THR   A HB   1 
ATOM   9731  H  HG1  . THR   B 1 313 ? 24.209  -19.868 26.399  1.00 40.85  ?  312 THR   A HG1  1 
ATOM   9732  H  HG21 . THR   B 1 313 ? 23.402  -21.629 27.939  1.00 39.02  ?  312 THR   A HG21 1 
ATOM   9733  H  HG22 . THR   B 1 313 ? 22.015  -21.228 28.577  1.00 39.02  ?  312 THR   A HG22 1 
ATOM   9734  H  HG23 . THR   B 1 313 ? 22.187  -21.242 27.007  1.00 39.02  ?  312 THR   A HG23 1 
ATOM   9735  N  N    . THR   B 1 314 ? 20.850  -18.513 25.956  1.00 39.69  ?  313 THR   A N    1 
ATOM   9736  C  CA   . THR   B 1 314 ? 20.053  -18.989 24.833  1.00 42.80  ?  313 THR   A CA   1 
ATOM   9737  C  C    . THR   B 1 314 ? 20.840  -19.882 23.885  1.00 39.09  ?  313 THR   A C    1 
ATOM   9738  O  O    . THR   B 1 314 ? 20.275  -20.393 22.933  1.00 46.61  ?  313 THR   A O    1 
ATOM   9739  C  CB   . THR   B 1 314 ? 19.484  -17.802 24.058  1.00 38.20  ?  313 THR   A CB   1 
ATOM   9740  O  OG1  . THR   B 1 314 ? 20.505  -17.104 23.341  1.00 37.18  ?  313 THR   A OG1  1 
ATOM   9741  C  CG2  . THR   B 1 314 ? 18.855  -16.799 25.032  1.00 46.15  ?  313 THR   A CG2  1 
ATOM   9742  H  H    . THR   B 1 314 ? 21.389  -17.878 25.740  1.00 47.62  ?  313 THR   A H    1 
ATOM   9743  H  HA   . THR   B 1 314 ? 19.310  -19.508 25.179  1.00 51.37  ?  313 THR   A HA   1 
ATOM   9744  H  HB   . THR   B 1 314 ? 18.825  -18.142 23.433  1.00 45.84  ?  313 THR   A HB   1 
ATOM   9745  H  HG1  . THR   B 1 314 ? 20.927  -16.598 23.861  1.00 44.61  ?  313 THR   A HG1  1 
ATOM   9746  H  HG21 . THR   B 1 314 ? 18.483  -16.049 24.542  1.00 55.38  ?  313 THR   A HG21 1 
ATOM   9747  H  HG22 . THR   B 1 314 ? 18.146  -17.227 25.537  1.00 55.38  ?  313 THR   A HG22 1 
ATOM   9748  H  HG23 . THR   B 1 314 ? 19.527  -16.470 25.649  1.00 55.38  ?  313 THR   A HG23 1 
ATOM   9749  N  N    . ILE   B 1 315 ? 22.104  -20.124 24.138  1.00 35.86  ?  314 ILE   A N    1 
ATOM   9750  C  CA   . ILE   B 1 315 ? 22.916  -20.868 23.191  1.00 39.68  ?  314 ILE   A CA   1 
ATOM   9751  C  C    . ILE   B 1 315 ? 22.364  -22.287 22.996  1.00 38.52  ?  314 ILE   A C    1 
ATOM   9752  O  O    . ILE   B 1 315 ? 21.742  -22.839 23.883  1.00 40.79  ?  314 ILE   A O    1 
ATOM   9753  C  CB   . ILE   B 1 315 ? 24.397  -20.852 23.647  1.00 35.90  ?  314 ILE   A CB   1 
ATOM   9754  C  CG1  . ILE   B 1 315 ? 24.982  -19.454 23.388  1.00 36.87  ?  314 ILE   A CG1  1 
ATOM   9755  C  CG2  . ILE   B 1 315 ? 25.207  -21.973 22.933  1.00 38.90  ?  314 ILE   A CG2  1 
ATOM   9756  C  CD1  . ILE   B 1 315 ? 26.494  -19.452 23.418  1.00 37.30  ?  314 ILE   A CD1  1 
HETATM 9757  ZN ZN   . ZN    C 2 .   ? -9.563  7.702   43.652  1.00 92.01  ?  401 ZN    B ZN   1 
HETATM 9758  ZN ZN   . ZN    D 2 .   ? 8.832   32.570  61.456  1.00 126.50 ?  402 ZN    B ZN   1 
HETATM 9759  C  C02  . A1LZ5 E 3 .   ? 19.269  7.582   44.144  1.00 25.82  ?  403 A1LZ5 B C02  1 
HETATM 9760  C  C03  . A1LZ5 E 3 .   ? 19.566  7.878   42.746  1.00 23.47  ?  403 A1LZ5 B C03  1 
HETATM 9761  C  C04  . A1LZ5 E 3 .   ? 19.733  9.162   42.263  1.00 29.24  ?  403 A1LZ5 B C04  1 
HETATM 9762  C  C05  . A1LZ5 E 3 .   ? 19.981  9.503   40.916  1.00 32.10  ?  403 A1LZ5 B C05  1 
HETATM 9763  C  C07  . A1LZ5 E 3 .   ? 19.651  11.329  39.175  1.00 34.58  ?  403 A1LZ5 B C07  1 
HETATM 9764  C  C08  . A1LZ5 E 3 .   ? 19.837  12.858  38.859  1.00 33.31  ?  403 A1LZ5 B C08  1 
HETATM 9765  C  C10  . A1LZ5 E 3 .   ? 19.815  15.166  39.650  1.00 32.80  ?  403 A1LZ5 B C10  1 
HETATM 9766  C  C11  . A1LZ5 E 3 .   ? 20.291  13.409  41.151  1.00 33.55  ?  403 A1LZ5 B C11  1 
HETATM 9767  C  C12  . A1LZ5 E 3 .   ? 20.263  11.940  41.582  1.00 31.68  ?  403 A1LZ5 B C12  1 
HETATM 9768  C  C13  . A1LZ5 E 3 .   ? 20.011  8.414   40.019  1.00 30.23  ?  403 A1LZ5 B C13  1 
HETATM 9769  C  C14  . A1LZ5 E 3 .   ? 19.829  7.086   40.483  1.00 29.34  ?  403 A1LZ5 B C14  1 
HETATM 9770  C  C15  . A1LZ5 E 3 .   ? 19.597  6.817   41.855  1.00 20.05  ?  403 A1LZ5 B C15  1 
HETATM 9771  C  C16  . A1LZ5 E 3 .   ? 19.348  5.402   42.399  1.00 27.82  ?  403 A1LZ5 B C16  1 
HETATM 9772  C  C18  . A1LZ5 E 3 .   ? 17.659  7.673   46.114  1.00 31.96  ?  403 A1LZ5 B C18  1 
HETATM 9773  C  C19  . A1LZ5 E 3 .   ? 17.277  6.204   46.252  1.00 29.20  ?  403 A1LZ5 B C19  1 
HETATM 9774  C  C20  . A1LZ5 E 3 .   ? 16.239  7.413   46.362  1.00 29.53  ?  403 A1LZ5 B C20  1 
HETATM 9775  C  C21  . A1LZ5 E 3 .   ? 18.436  8.220   47.200  1.00 27.32  ?  403 A1LZ5 B C21  1 
HETATM 9776  C  C22  . A1LZ5 E 3 .   ? 18.614  9.484   47.756  1.00 32.67  ?  403 A1LZ5 B C22  1 
HETATM 9777  C  C23  . A1LZ5 E 3 .   ? 17.948  10.641  47.447  1.00 38.31  ?  403 A1LZ5 B C23  1 
HETATM 9778  C  C24  . A1LZ5 E 3 .   ? 18.216  11.892  48.122  1.00 45.59  ?  403 A1LZ5 B C24  1 
HETATM 9779  C  C25  . A1LZ5 E 3 .   ? 19.142  12.192  49.149  1.00 37.15  ?  403 A1LZ5 B C25  1 
HETATM 9780  C  C26  . A1LZ5 E 3 .   ? 19.734  10.976  49.315  1.00 32.02  ?  403 A1LZ5 B C26  1 
HETATM 9781  C  C27  . A1LZ5 E 3 .   ? 20.776  11.048  50.438  1.00 31.80  ?  403 A1LZ5 B C27  1 
HETATM 9782  C  C28  . A1LZ5 E 3 .   ? 21.209  9.488   50.373  1.00 32.26  ?  403 A1LZ5 B C28  1 
HETATM 9783  C  C29  . A1LZ5 E 3 .   ? 19.512  9.815   48.723  1.00 34.62  ?  403 A1LZ5 B C29  1 
HETATM 9784  C  C30  . A1LZ5 E 3 .   ? 20.384  8.785   49.275  1.00 38.99  ?  403 A1LZ5 B C30  1 
HETATM 9785  C  C31  . A1LZ5 E 3 .   ? 20.213  7.608   48.721  1.00 28.52  ?  403 A1LZ5 B C31  1 
HETATM 9786  C  C32  . A1LZ5 E 3 .   ? 19.313  7.270   47.704  1.00 31.35  ?  403 A1LZ5 B C32  1 
HETATM 9787  N  N06  . A1LZ5 E 3 .   ? 20.209  10.863  40.491  1.00 33.92  ?  403 A1LZ5 B N06  1 
HETATM 9788  N  N09  . A1LZ5 E 3 .   ? 19.486  13.744  39.992  1.00 40.98  ?  403 A1LZ5 B N09  1 
HETATM 9789  N  N17  . A1LZ5 E 3 .   ? 18.085  8.039   44.763  1.00 35.59  ?  403 A1LZ5 B N17  1 
HETATM 9790  O  O01  . A1LZ5 E 3 .   ? 19.931  6.782   44.751  1.00 30.39  ?  403 A1LZ5 B O01  1 
HETATM 9791  C  C02  . A1LZ5 F 3 .   ? 49.538  -7.355  41.501  1.00 26.74  ?  401 A1LZ5 A C02  1 
HETATM 9792  C  C03  . A1LZ5 F 3 .   ? 49.850  -7.671  42.923  1.00 23.62  ?  401 A1LZ5 A C03  1 
HETATM 9793  C  C04  . A1LZ5 F 3 .   ? 50.022  -8.965  43.354  1.00 24.45  ?  401 A1LZ5 A C04  1 
HETATM 9794  C  C05  . A1LZ5 F 3 .   ? 50.284  -9.349  44.673  1.00 31.74  ?  401 A1LZ5 A C05  1 
HETATM 9795  C  C07  . A1LZ5 F 3 .   ? 50.253  -11.195 46.398  1.00 38.18  ?  401 A1LZ5 A C07  1 
HETATM 9796  C  C08  . A1LZ5 F 3 .   ? 50.519  -12.724 46.641  1.00 34.35  ?  401 A1LZ5 A C08  1 
HETATM 9797  C  C10  . A1LZ5 F 3 .   ? 50.234  -14.963 45.926  1.00 41.36  ?  401 A1LZ5 A C10  1 
HETATM 9798  C  C11  . A1LZ5 F 3 .   ? 50.392  -13.228 44.345  1.00 37.99  ?  401 A1LZ5 A C11  1 
HETATM 9799  C  C12  . A1LZ5 F 3 .   ? 50.164  -11.750 43.970  1.00 31.13  ?  401 A1LZ5 A C12  1 
HETATM 9800  C  C13  . A1LZ5 F 3 .   ? 50.305  -8.274  45.655  1.00 29.94  ?  401 A1LZ5 A C13  1 
HETATM 9801  C  C14  . A1LZ5 F 3 .   ? 50.088  -6.934  45.223  1.00 27.07  ?  401 A1LZ5 A C14  1 
HETATM 9802  C  C15  . A1LZ5 F 3 .   ? 49.834  -6.638  43.836  1.00 19.50  ?  401 A1LZ5 A C15  1 
HETATM 9803  C  C16  . A1LZ5 F 3 .   ? 49.540  -5.227  43.327  1.00 24.74  ?  401 A1LZ5 A C16  1 
HETATM 9804  C  C18  . A1LZ5 F 3 .   ? 47.978  -7.442  39.525  1.00 27.51  ?  401 A1LZ5 A C18  1 
HETATM 9805  C  C19  . A1LZ5 F 3 .   ? 47.700  -5.975  39.330  1.00 30.23  ?  401 A1LZ5 A C19  1 
HETATM 9806  C  C20  . A1LZ5 F 3 .   ? 46.528  -7.048  39.274  1.00 26.52  ?  401 A1LZ5 A C20  1 
HETATM 9807  C  C21  . A1LZ5 F 3 .   ? 48.715  -8.009  38.426  1.00 26.14  ?  401 A1LZ5 A C21  1 
HETATM 9808  C  C22  . A1LZ5 F 3 .   ? 48.860  -9.242  37.833  1.00 30.75  ?  401 A1LZ5 A C22  1 
HETATM 9809  C  C23  . A1LZ5 F 3 .   ? 48.145  -10.376 38.108  1.00 29.34  ?  401 A1LZ5 A C23  1 
HETATM 9810  C  C24  . A1LZ5 F 3 .   ? 48.332  -11.616 37.377  1.00 34.16  ?  401 A1LZ5 A C24  1 
HETATM 9811  C  C25  . A1LZ5 F 3 .   ? 49.264  -11.905 36.306  1.00 33.94  ?  401 A1LZ5 A C25  1 
HETATM 9812  C  C26  . A1LZ5 F 3 .   ? 49.927  -10.695 36.182  1.00 29.64  ?  401 A1LZ5 A C26  1 
HETATM 9813  C  C27  . A1LZ5 F 3 .   ? 50.982  -10.735 35.064  1.00 29.00  ?  401 A1LZ5 A C27  1 
HETATM 9814  C  C28  . A1LZ5 F 3 .   ? 51.432  -9.216  35.184  1.00 28.29  ?  401 A1LZ5 A C28  1 
HETATM 9815  C  C29  . A1LZ5 F 3 .   ? 49.748  -9.551  36.812  1.00 29.04  ?  401 A1LZ5 A C29  1 
HETATM 9816  C  C30  . A1LZ5 F 3 .   ? 50.693  -8.557  36.293  1.00 32.44  ?  401 A1LZ5 A C30  1 
HETATM 9817  C  C31  . A1LZ5 F 3 .   ? 50.553  -7.404  36.904  1.00 32.75  ?  401 A1LZ5 A C31  1 
HETATM 9818  C  C32  . A1LZ5 F 3 .   ? 49.616  -7.074  37.944  1.00 30.32  ?  401 A1LZ5 A C32  1 
HETATM 9819  N  N06  . A1LZ5 F 3 .   ? 50.532  -10.730 44.995  1.00 35.66  ?  401 A1LZ5 A N06  1 
HETATM 9820  N  N09  . A1LZ5 F 3 .   ? 49.897  -13.564 45.661  1.00 44.74  ?  401 A1LZ5 A N09  1 
HETATM 9821  N  N17  . A1LZ5 F 3 .   ? 48.394  -7.803  40.873  1.00 30.10  ?  401 A1LZ5 A N17  1 
HETATM 9822  O  O01  . A1LZ5 F 3 .   ? 50.247  -6.575  40.869  1.00 27.76  ?  401 A1LZ5 A O01  1 
HETATM 9823  ZN ZN   . ZN    G 2 .   ? 38.742  -31.161 22.430  1.00 88.46  ?  402 ZN    A ZN   1 
HETATM 9824  ZN ZN   . ZN    H 2 .   ? 20.204  -7.797  42.140  1.00 88.26  ?  403 ZN    A ZN   1 
HETATM 9825  O  O    . HOH   I 4 .   ? 12.385  -6.154  51.200  1.00 51.80  ?  501 HOH   B O    1 
HETATM 9826  O  O    . HOH   I 4 .   ? 21.891  5.329   12.459  1.00 47.75  ?  502 HOH   B O    1 
HETATM 9827  O  O    . HOH   I 4 .   ? 3.556   -10.251 30.940  1.00 43.91  ?  503 HOH   B O    1 
HETATM 9828  O  O    . HOH   I 4 .   ? -4.492  18.109  58.114  1.00 44.07  ?  504 HOH   B O    1 
HETATM 9829  O  O    . HOH   I 4 .   ? 9.497   14.761  17.635  1.00 56.55  ?  505 HOH   B O    1 
HETATM 9830  O  O    . HOH   I 4 .   ? 16.502  12.367  43.100  1.00 38.14  ?  506 HOH   B O    1 
HETATM 9831  O  O    . HOH   I 4 .   ? -1.179  12.726  13.624  1.00 41.30  ?  507 HOH   B O    1 
HETATM 9832  O  O    . HOH   I 4 .   ? 18.424  2.569   32.536  1.00 29.60  ?  508 HOH   B O    1 
HETATM 9833  O  O    . HOH   I 4 .   ? -14.304 12.813  47.715  1.00 34.07  ?  509 HOH   B O    1 
HETATM 9834  O  O    . HOH   I 4 .   ? 7.660   12.622  45.907  1.00 34.09  ?  510 HOH   B O    1 
HETATM 9835  O  O    . HOH   I 4 .   ? 13.539  -5.655  37.191  1.00 38.08  ?  511 HOH   B O    1 
HETATM 9836  O  O    . HOH   I 4 .   ? 3.478   -1.361  11.553  1.00 41.53  ?  512 HOH   B O    1 
HETATM 9837  O  O    . HOH   I 4 .   ? 5.742   4.037   20.398  1.00 38.91  ?  513 HOH   B O    1 
HETATM 9838  O  O    . HOH   I 4 .   ? -3.300  -8.940  42.019  1.00 40.88  ?  514 HOH   B O    1 
HETATM 9839  O  O    . HOH   I 4 .   ? 6.797   2.326   44.672  1.00 38.60  ?  515 HOH   B O    1 
HETATM 9840  O  O    . HOH   I 4 .   ? 15.384  10.394  55.322  1.00 37.38  ?  516 HOH   B O    1 
HETATM 9841  O  O    . HOH   I 4 .   ? -4.182  3.792   49.806  1.00 35.28  ?  517 HOH   B O    1 
HETATM 9842  O  O    . HOH   I 4 .   ? 9.060   14.412  45.513  1.00 39.85  ?  518 HOH   B O    1 
HETATM 9843  O  O    . HOH   I 4 .   ? -7.258  10.887  53.148  1.00 37.06  ?  519 HOH   B O    1 
HETATM 9844  O  O    . HOH   I 4 .   ? 13.040  -4.932  42.010  1.00 30.92  ?  520 HOH   B O    1 
HETATM 9845  O  O    . HOH   I 4 .   ? 10.606  -4.548  41.540  1.00 38.43  ?  521 HOH   B O    1 
HETATM 9846  O  O    . HOH   I 4 .   ? -5.127  -0.041  39.077  1.00 31.95  ?  522 HOH   B O    1 
HETATM 9847  O  O    . HOH   I 4 .   ? -13.013 17.083  51.433  1.00 39.23  ?  523 HOH   B O    1 
HETATM 9848  O  O    . HOH   I 4 .   ? -6.398  25.158  58.832  1.00 52.85  ?  524 HOH   B O    1 
HETATM 9849  O  O    . HOH   I 4 .   ? 25.008  0.323   46.672  1.00 34.71  ?  525 HOH   B O    1 
HETATM 9850  O  O    . HOH   I 4 .   ? 13.198  7.170   44.693  1.00 28.72  ?  526 HOH   B O    1 
HETATM 9851  O  O    . HOH   I 4 .   ? 0.950   10.990  14.936  1.00 38.81  ?  527 HOH   B O    1 
HETATM 9852  O  O    . HOH   I 4 .   ? 17.860  7.970   26.132  1.00 39.28  ?  528 HOH   B O    1 
HETATM 9853  O  O    . HOH   I 4 .   ? -2.405  -2.014  45.794  1.00 29.22  ?  529 HOH   B O    1 
HETATM 9854  O  O    . HOH   I 4 .   ? 2.081   2.947   56.774  1.00 39.79  ?  530 HOH   B O    1 
HETATM 9855  O  O    . HOH   I 4 .   ? 1.385   24.942  41.096  1.00 44.72  ?  531 HOH   B O    1 
HETATM 9856  O  O    . HOH   I 4 .   ? 2.709   14.405  48.146  1.00 31.37  ?  532 HOH   B O    1 
HETATM 9857  O  O    . HOH   I 4 .   ? 16.902  9.267   37.310  1.00 40.63  ?  533 HOH   B O    1 
HETATM 9858  O  O    . HOH   I 4 .   ? 23.499  5.818   38.550  1.00 35.90  ?  534 HOH   B O    1 
HETATM 9859  O  O    . HOH   I 4 .   ? 9.536   -9.871  26.059  1.00 44.32  ?  535 HOH   B O    1 
HETATM 9860  O  O    . HOH   I 4 .   ? 12.563  7.435   54.199  1.00 33.10  ?  536 HOH   B O    1 
HETATM 9861  O  O    . HOH   I 4 .   ? 8.402   16.877  15.534  1.00 46.20  ?  537 HOH   B O    1 
HETATM 9862  O  O    . HOH   I 4 .   ? 14.612  10.553  45.497  1.00 31.63  ?  538 HOH   B O    1 
HETATM 9863  O  O    . HOH   I 4 .   ? 14.634  -9.071  31.824  1.00 32.48  ?  539 HOH   B O    1 
HETATM 9864  O  O    . HOH   I 4 .   ? 19.268  8.175   52.952  1.00 46.32  ?  540 HOH   B O    1 
HETATM 9865  O  O    . HOH   I 4 .   ? 0.675   7.742   56.891  1.00 33.57  ?  541 HOH   B O    1 
HETATM 9866  O  O    . HOH   I 4 .   ? 14.129  -10.159 38.504  1.00 27.72  ?  542 HOH   B O    1 
HETATM 9867  O  O    . HOH   I 4 .   ? 15.220  -8.552  40.476  1.00 29.56  ?  543 HOH   B O    1 
HETATM 9868  O  O    . HOH   I 4 .   ? -4.654  3.719   23.846  1.00 54.25  ?  544 HOH   B O    1 
HETATM 9869  O  O    . HOH   I 4 .   ? 18.115  -0.055  31.879  1.00 31.02  ?  545 HOH   B O    1 
HETATM 9870  O  O    . HOH   I 4 .   ? -1.605  15.159  20.414  1.00 49.26  ?  546 HOH   B O    1 
HETATM 9871  O  O    . HOH   I 4 .   ? -0.508  0.290   13.084  1.00 52.74  ?  547 HOH   B O    1 
HETATM 9872  O  O    . HOH   I 4 .   ? -5.348  6.502   42.268  1.00 35.21  ?  548 HOH   B O    1 
HETATM 9873  O  O    . HOH   I 4 .   ? 10.616  -10.404 46.732  1.00 36.37  ?  549 HOH   B O    1 
HETATM 9874  O  O    . HOH   I 4 .   ? 9.434   9.879   56.972  1.00 38.40  ?  550 HOH   B O    1 
HETATM 9875  O  O    . HOH   I 4 .   ? -7.324  4.633   41.918  1.00 34.41  ?  551 HOH   B O    1 
HETATM 9876  O  O    . HOH   I 4 .   ? 4.636   -1.153  25.902  1.00 32.85  ?  552 HOH   B O    1 
HETATM 9877  O  O    . HOH   I 4 .   ? 18.626  -14.039 31.613  1.00 38.22  ?  553 HOH   B O    1 
HETATM 9878  O  O    . HOH   I 4 .   ? 3.263   3.698   21.586  1.00 34.12  ?  554 HOH   B O    1 
HETATM 9879  O  O    . HOH   I 4 .   ? 1.212   17.441  28.647  1.00 50.30  ?  555 HOH   B O    1 
HETATM 9880  O  O    . HOH   I 4 .   ? 19.130  2.439   51.997  1.00 41.37  ?  556 HOH   B O    1 
HETATM 9881  O  O    . HOH   I 4 .   ? 13.244  -2.313  -11.081 1.00 42.93  ?  557 HOH   B O    1 
HETATM 9882  O  O    . HOH   I 4 .   ? -7.028  -1.653  32.889  1.00 49.80  ?  558 HOH   B O    1 
HETATM 9883  O  O    . HOH   I 4 .   ? 9.302   -15.783 43.725  1.00 49.29  ?  559 HOH   B O    1 
HETATM 9884  O  O    . HOH   I 4 .   ? 2.356   16.389  27.083  1.00 41.04  ?  560 HOH   B O    1 
HETATM 9885  O  O    . HOH   I 4 .   ? 2.580   5.018   56.112  1.00 29.70  ?  561 HOH   B O    1 
HETATM 9886  O  O    . HOH   I 4 .   ? 16.764  11.892  37.098  1.00 40.24  ?  562 HOH   B O    1 
HETATM 9887  O  O    . HOH   I 4 .   ? 21.303  -1.336  16.276  1.00 49.24  ?  563 HOH   B O    1 
HETATM 9888  O  O    . HOH   I 4 .   ? 10.043  19.442  22.789  1.00 53.38  ?  564 HOH   B O    1 
HETATM 9889  O  O    . HOH   I 4 .   ? 7.568   -11.149 28.304  1.00 41.80  ?  565 HOH   B O    1 
HETATM 9890  O  O    . HOH   I 4 .   ? 10.183  -0.788  12.652  1.00 35.84  ?  566 HOH   B O    1 
HETATM 9891  O  O    . HOH   I 4 .   ? -4.563  -2.845  51.056  1.00 34.36  ?  567 HOH   B O    1 
HETATM 9892  O  O    . HOH   I 4 .   ? 6.743   -15.789 50.544  1.00 43.01  ?  568 HOH   B O    1 
HETATM 9893  O  O    . HOH   I 4 .   ? 20.868  0.290   52.383  1.00 46.77  ?  569 HOH   B O    1 
HETATM 9894  O  O    . HOH   I 4 .   ? 18.654  13.497  44.827  1.00 37.05  ?  570 HOH   B O    1 
HETATM 9895  O  O    . HOH   I 4 .   ? 16.728  -8.056  -12.607 1.00 46.83  ?  571 HOH   B O    1 
HETATM 9896  O  O    . HOH   I 4 .   ? 24.575  6.799   50.129  1.00 36.74  ?  572 HOH   B O    1 
HETATM 9897  O  O    . HOH   I 4 .   ? 14.618  -6.009  40.095  1.00 27.31  ?  573 HOH   B O    1 
HETATM 9898  O  O    . HOH   I 4 .   ? 7.815   -3.461  19.502  1.00 42.86  ?  574 HOH   B O    1 
HETATM 9899  O  O    . HOH   I 4 .   ? 13.535  -10.872 46.556  1.00 50.55  ?  575 HOH   B O    1 
HETATM 9900  O  O    . HOH   I 4 .   ? 22.017  -7.560  32.513  1.00 37.47  ?  576 HOH   B O    1 
HETATM 9901  O  O    . HOH   I 4 .   ? 12.619  12.783  16.909  1.00 54.91  ?  577 HOH   B O    1 
HETATM 9902  O  O    . HOH   I 4 .   ? -9.493  10.845  52.839  1.00 42.19  ?  578 HOH   B O    1 
HETATM 9903  O  O    . HOH   I 4 .   ? 18.539  5.274   24.880  1.00 50.70  ?  579 HOH   B O    1 
HETATM 9904  O  O    . HOH   I 4 .   ? 2.909   1.090   21.776  1.00 39.60  ?  580 HOH   B O    1 
HETATM 9905  O  O    . HOH   I 4 .   ? -8.348  19.000  31.571  1.00 58.18  ?  581 HOH   B O    1 
HETATM 9906  O  O    . HOH   I 4 .   ? 11.396  14.790  16.319  1.00 52.50  ?  582 HOH   B O    1 
HETATM 9907  O  O    . HOH   I 4 .   ? 20.570  6.173   52.446  1.00 40.74  ?  583 HOH   B O    1 
HETATM 9908  O  O    . HOH   I 4 .   ? -10.266 18.981  33.605  1.00 65.07  ?  584 HOH   B O    1 
HETATM 9909  O  O    . HOH   J 4 .   ? 42.618  6.479   34.629  1.00 64.58  ?  501 HOH   A O    1 
HETATM 9910  O  O    . HOH   J 4 .   ? 17.965  -12.017 35.852  1.00 38.86  ?  502 HOH   A O    1 
HETATM 9911  O  O    . HOH   J 4 .   ? 52.589  -5.643  72.668  1.00 52.43  ?  503 HOH   A O    1 
HETATM 9912  O  O    . HOH   J 4 .   ? 27.199  10.716  39.628  1.00 46.34  ?  504 HOH   A O    1 
HETATM 9913  O  O    . HOH   J 4 .   ? 47.016  -12.330 48.633  1.00 42.26  ?  505 HOH   A O    1 
HETATM 9914  O  O    . HOH   J 4 .   ? 25.425  -17.471 27.677  1.00 29.33  ?  506 HOH   A O    1 
HETATM 9915  O  O    . HOH   J 4 .   ? 43.438  -8.415  38.674  1.00 30.75  ?  507 HOH   A O    1 
HETATM 9916  O  O    . HOH   J 4 .   ? 18.951  -21.841 27.954  1.00 42.19  ?  508 HOH   A O    1 
HETATM 9917  O  O    . HOH   J 4 .   ? 36.196  2.791   62.148  1.00 40.32  ?  509 HOH   A O    1 
HETATM 9918  O  O    . HOH   J 4 .   ? 46.785  -11.329 69.110  1.00 40.29  ?  510 HOH   A O    1 
HETATM 9919  O  O    . HOH   J 4 .   ? 42.178  -18.754 70.010  1.00 45.72  ?  511 HOH   A O    1 
HETATM 9920  O  O    . HOH   J 4 .   ? 34.898  3.807   77.873  1.00 33.73  ?  512 HOH   A O    1 
HETATM 9921  O  O    . HOH   J 4 .   ? 46.248  3.207   38.239  1.00 46.26  ?  513 HOH   A O    1 
HETATM 9922  O  O    . HOH   J 4 .   ? 27.496  -6.424  66.739  1.00 36.34  ?  514 HOH   A O    1 
HETATM 9923  O  O    . HOH   J 4 .   ? 36.225  -4.292  67.774  1.00 37.03  ?  515 HOH   A O    1 
HETATM 9924  O  O    . HOH   J 4 .   ? 38.739  -17.415 70.450  1.00 45.58  ?  516 HOH   A O    1 
HETATM 9925  O  O    . HOH   J 4 .   ? 27.895  2.233   40.102  1.00 30.59  ?  517 HOH   A O    1 
HETATM 9926  O  O    . HOH   J 4 .   ? 31.576  -35.114 27.960  1.00 42.52  ?  518 HOH   A O    1 
HETATM 9927  O  O    . HOH   J 4 .   ? 32.900  -14.329 37.525  1.00 31.48  ?  519 HOH   A O    1 
HETATM 9928  O  O    . HOH   J 4 .   ? 32.390  -20.400 48.345  1.00 59.93  ?  520 HOH   A O    1 
HETATM 9929  O  O    . HOH   J 4 .   ? 60.657  -1.418  73.847  1.00 56.92  ?  521 HOH   A O    1 
HETATM 9930  O  O    . HOH   J 4 .   ? 45.140  -8.611  50.238  1.00 43.35  ?  522 HOH   A O    1 
HETATM 9931  O  O    . HOH   J 4 .   ? 23.021  -10.397 32.543  1.00 41.57  ?  523 HOH   A O    1 
HETATM 9932  O  O    . HOH   J 4 .   ? 40.620  4.939   44.438  1.00 42.15  ?  524 HOH   A O    1 
HETATM 9933  O  O    . HOH   J 4 .   ? 37.190  -2.141  41.138  1.00 34.10  ?  525 HOH   A O    1 
HETATM 9934  O  O    . HOH   J 4 .   ? 42.884  -7.103  31.553  1.00 30.32  ?  526 HOH   A O    1 
HETATM 9935  O  O    . HOH   J 4 .   ? 17.378  -16.978 34.562  1.00 32.45  ?  527 HOH   A O    1 
HETATM 9936  O  O    . HOH   J 4 .   ? 48.666  -2.536  53.367  1.00 32.38  ?  528 HOH   A O    1 
HETATM 9937  O  O    . HOH   J 4 .   ? 43.382  -6.880  41.242  1.00 27.96  ?  529 HOH   A O    1 
HETATM 9938  O  O    . HOH   J 4 .   ? 50.362  -3.596  34.888  1.00 43.41  ?  530 HOH   A O    1 
HETATM 9939  O  O    . HOH   J 4 .   ? 49.355  -7.962  32.495  1.00 36.57  ?  531 HOH   A O    1 
HETATM 9940  O  O    . HOH   J 4 .   ? 38.528  14.452  48.265  1.00 37.43  ?  532 HOH   A O    1 
HETATM 9941  O  O    . HOH   J 4 .   ? 28.725  -9.698  18.215  1.00 57.78  ?  533 HOH   A O    1 
HETATM 9942  O  O    . HOH   J 4 .   ? 43.951  5.430   48.532  1.00 27.96  ?  534 HOH   A O    1 
HETATM 9943  O  O    . HOH   J 4 .   ? 39.406  7.503   62.234  1.00 58.62  ?  535 HOH   A O    1 
HETATM 9944  O  O    . HOH   J 4 .   ? 26.927  9.372   43.166  1.00 38.60  ?  536 HOH   A O    1 
HETATM 9945  O  O    . HOH   J 4 .   ? 43.782  2.057   96.390  1.00 43.58  ?  537 HOH   A O    1 
HETATM 9946  O  O    . HOH   J 4 .   ? 31.261  -11.065 70.975  1.00 38.01  ?  538 HOH   A O    1 
HETATM 9947  O  O    . HOH   J 4 .   ? 29.127  -18.283 51.501  1.00 45.94  ?  539 HOH   A O    1 
HETATM 9948  O  O    . HOH   J 4 .   ? 22.791  -10.799 28.897  1.00 41.08  ?  540 HOH   A O    1 
HETATM 9949  O  O    . HOH   J 4 .   ? 28.722  -14.822 65.340  1.00 38.84  ?  541 HOH   A O    1 
HETATM 9950  O  O    . HOH   J 4 .   ? 43.185  5.164   43.908  1.00 34.27  ?  542 HOH   A O    1 
HETATM 9951  O  O    . HOH   J 4 .   ? 53.939  -5.584  47.247  1.00 37.08  ?  543 HOH   A O    1 
HETATM 9952  O  O    . HOH   J 4 .   ? 44.978  9.171   54.161  1.00 31.39  ?  544 HOH   A O    1 
HETATM 9953  O  O    . HOH   J 4 .   ? 44.929  -10.372 40.260  1.00 34.99  ?  545 HOH   A O    1 
HETATM 9954  O  O    . HOH   J 4 .   ? 25.025  -6.256  43.356  1.00 31.72  ?  546 HOH   A O    1 
HETATM 9955  O  O    . HOH   J 4 .   ? 25.619  -0.464  38.806  1.00 39.06  ?  547 HOH   A O    1 
HETATM 9956  O  O    . HOH   J 4 .   ? 40.681  0.515   73.013  1.00 32.80  ?  548 HOH   A O    1 
HETATM 9957  O  O    . HOH   J 4 .   ? 46.403  5.985   34.624  1.00 37.75  ?  549 HOH   A O    1 
HETATM 9958  O  O    . HOH   J 4 .   ? 54.326  -3.507  48.582  1.00 41.56  ?  550 HOH   A O    1 
HETATM 9959  O  O    . HOH   J 4 .   ? 19.649  -14.461 28.267  1.00 43.46  ?  551 HOH   A O    1 
HETATM 9960  O  O    . HOH   J 4 .   ? 39.960  9.752   60.047  1.00 50.02  ?  552 HOH   A O    1 
HETATM 9961  O  O    . HOH   J 4 .   ? 43.685  10.715  39.230  1.00 39.79  ?  553 HOH   A O    1 
HETATM 9962  O  O    . HOH   J 4 .   ? 24.552  -8.018  33.866  1.00 41.83  ?  554 HOH   A O    1 
HETATM 9963  O  O    . HOH   J 4 .   ? 48.499  -0.213  53.770  1.00 32.19  ?  555 HOH   A O    1 
HETATM 9964  O  O    . HOH   J 4 .   ? 43.054  11.077  62.282  1.00 66.76  ?  556 HOH   A O    1 
HETATM 9965  O  O    . HOH   J 4 .   ? 38.894  -18.396 37.365  1.00 44.33  ?  557 HOH   A O    1 
HETATM 9966  O  O    . HOH   J 4 .   ? 33.002  -4.598  29.770  1.00 39.89  ?  558 HOH   A O    1 
HETATM 9967  O  O    . HOH   J 4 .   ? 25.610  3.303   34.654  1.00 31.29  ?  559 HOH   A O    1 
HETATM 9968  O  O    . HOH   J 4 .   ? 26.409  1.180   36.077  1.00 38.18  ?  560 HOH   A O    1 
HETATM 9969  O  O    . HOH   J 4 .   ? 34.993  1.245   59.929  1.00 36.49  ?  561 HOH   A O    1 
HETATM 9970  O  O    . HOH   J 4 .   ? 29.272  -12.459 72.219  1.00 34.25  ?  562 HOH   A O    1 
HETATM 9971  O  O    . HOH   J 4 .   ? 23.745  -24.753 26.831  1.00 45.79  ?  563 HOH   A O    1 
HETATM 9972  O  O    . HOH   J 4 .   ? 15.830  -12.629 38.190  1.00 36.50  ?  564 HOH   A O    1 
HETATM 9973  O  O    . HOH   J 4 .   ? 28.215  -17.866 20.819  1.00 42.97  ?  565 HOH   A O    1 
HETATM 9974  O  O    . HOH   J 4 .   ? 26.304  -3.762  35.840  1.00 39.15  ?  566 HOH   A O    1 
HETATM 9975  O  O    . HOH   J 4 .   ? 22.707  -4.632  43.909  1.00 33.35  ?  567 HOH   A O    1 
HETATM 9976  O  O    . HOH   J 4 .   ? 44.693  10.476  47.241  1.00 25.61  ?  568 HOH   A O    1 
HETATM 9977  O  O    . HOH   J 4 .   ? 28.271  10.556  30.002  1.00 49.84  ?  569 HOH   A O    1 
HETATM 9978  O  O    . HOH   J 4 .   ? 41.314  12.251  61.203  1.00 57.14  ?  570 HOH   A O    1 
HETATM 9979  O  O    . HOH   J 4 .   ? 30.874  -7.289  28.956  1.00 29.61  ?  571 HOH   A O    1 
HETATM 9980  O  O    . HOH   J 4 .   ? 38.098  -12.261 39.493  1.00 41.05  ?  572 HOH   A O    1 
HETATM 9981  O  O    . HOH   J 4 .   ? 33.923  -3.651  64.168  1.00 28.34  ?  573 HOH   A O    1 
HETATM 9982  O  O    . HOH   J 4 .   ? 41.933  -13.812 68.627  1.00 42.64  ?  574 HOH   A O    1 
HETATM 9983  O  O    . HOH   J 4 .   ? 28.374  -32.931 31.702  1.00 44.50  ?  575 HOH   A O    1 
HETATM 9984  O  O    . HOH   J 4 .   ? 49.069  -13.388 40.526  1.00 49.19  ?  576 HOH   A O    1 
HETATM 9985  O  O    . HOH   J 4 .   ? 49.479  -1.999  33.353  1.00 41.03  ?  577 HOH   A O    1 
HETATM 9986  O  O    . HOH   J 4 .   ? 45.612  8.598   45.523  1.00 33.03  ?  578 HOH   A O    1 
HETATM 9987  O  O    . HOH   J 4 .   ? 20.625  -13.825 42.895  1.00 38.19  ?  579 HOH   A O    1 
HETATM 9988  O  O    . HOH   J 4 .   ? 51.238  0.018   33.083  1.00 34.21  ?  580 HOH   A O    1 
HETATM 9989  O  O    . HOH   J 4 .   ? 39.427  -14.526 40.224  1.00 37.54  ?  581 HOH   A O    1 
HETATM 9990  O  O    . HOH   J 4 .   ? 45.658  -10.398 29.958  1.00 31.29  ?  582 HOH   A O    1 
HETATM 9991  O  O    . HOH   J 4 .   ? 45.084  5.937   45.840  1.00 22.62  ?  583 HOH   A O    1 
HETATM 9992  O  O    . HOH   J 4 .   ? 47.484  -9.747  48.369  1.00 41.99  ?  584 HOH   A O    1 
HETATM 9993  O  O    . HOH   J 4 .   ? 29.200  8.563   29.556  1.00 58.80  ?  585 HOH   A O    1 
HETATM 9994  O  O    . HOH   J 4 .   ? 37.499  -18.112 56.370  1.00 58.17  ?  586 HOH   A O    1 
HETATM 9995  O  O    . HOH   J 4 .   ? 39.440  -17.131 29.538  1.00 37.86  ?  587 HOH   A O    1 
HETATM 9996  O  O    . HOH   J 4 .   ? 33.386  -1.278  64.160  1.00 39.04  ?  588 HOH   A O    1 
HETATM 9997  O  O    . HOH   J 4 .   ? 38.890  -32.768 25.473  1.00 67.87  ?  589 HOH   A O    1 
HETATM 9998  O  O    . HOH   J 4 .   ? 24.481  -2.931  34.404  1.00 48.90  ?  590 HOH   A O    1 
HETATM 9999  O  O    . HOH   J 4 .   ? 38.953  -17.760 40.163  1.00 36.43  ?  591 HOH   A O    1 
HETATM 10000 O  O    . HOH   J 4 .   ? 25.878  -6.993  31.645  1.00 50.15  ?  592 HOH   A O    1 
HETATM 10001 O  O    . HOH   J 4 .   ? 51.901  5.305   44.319  1.00 47.94  ?  593 HOH   A O    1 
HETATM 10002 O  O    . HOH   J 4 .   ? 30.847  -20.211 50.035  1.00 52.15  ?  594 HOH   A O    1 
HETATM 10003 O  O    . HOH   J 4 .   ? 41.938  -8.011  29.536  1.00 32.37  ?  595 HOH   A O    1 
HETATM 10004 O  O    . HOH   J 4 .   ? 51.726  -5.955  33.419  1.00 53.37  ?  596 HOH   A O    1 
HETATM 10005 O  O    . HOH   J 4 .   ? 28.598  -10.029 15.968  1.00 62.35  ?  597 HOH   A O    1 
HETATM 10006 O  O    . HOH   J 4 .   ? 50.519  -10.089 31.229  1.00 34.97  ?  598 HOH   A O    1 
HETATM 10007 O  O    . HOH   J 4 .   ? 43.382  -10.098 28.274  1.00 40.64  ?  599 HOH   A O    1 
HETATM 10008 O  O    . HOH   J 4 .   ? 39.988  -19.268 55.385  1.00 59.66  ?  600 HOH   A O    1 
HETATM 10009 O  O    . HOH   J 4 .   ? 50.034  -12.987 31.787  1.00 42.39  ?  601 HOH   A O    1 
# 
