data_8YND
# 
_entry.id   8YND 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8YND         pdb_00008ynd 10.2210/pdb8ynd/pdb 
WWPDB D_1300045964 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-19 ? 
2 'Structure model' 1 1 2025-02-26 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'              
2  2 'Structure model' '_citation.journal_abbrev'       
3  2 'Structure model' '_citation.journal_id_CSD'       
4  2 'Structure model' '_citation.journal_id_ISSN'      
5  2 'Structure model' '_citation.journal_volume'       
6  2 'Structure model' '_citation.page_first'           
7  2 'Structure model' '_citation.page_last'            
8  2 'Structure model' '_citation.pdbx_database_id_DOI' 
9  2 'Structure model' '_citation.title'                
10 2 'Structure model' '_citation.year'                 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8YND 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yanyaqian@sjtu.edu.cn 
_pdbx_contact_author.name_first         yaqian 
_pdbx_contact_author.name_last          yan 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0009-0008-0232-1517 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Xu, M.J.'  1 0000-0003-1768-208X 
'Yan, Y.Q.' 2 0009-0008-0232-1517 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acs Catalysis' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2155-5435 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                2550 
_citation.page_last                 2560 
_citation.title                     
;Structural Insights into the Substrate Recognition Mechanism of an ATP-Grasp Peptide-Ligase Producing Diverse Dipeptides Containing Unnatural Amino Acids
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acscatal.4c07750 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yan, Y.Q.'   1  ? 
primary 'Li, S.Y.'    2  ? 
primary 'Wu, X.N.'    3  ? 
primary 'Zhou, T.'    4  ? 
primary 'Li, J.X.'    5  ? 
primary 'Huang, S.X.' 6  ? 
primary 'Zheng, J.T.' 7  ? 
primary 'Xu, J.'      8  ? 
primary 'Da, L.T.'    9  ? 
primary 'Xu, M.J.'    10 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'ATP-grasp peptide ligase' 49193.633 8    ? ? ? 'SRA: SRR28004724' 
2 water   nat water                      18.015    1455 ? ? ? ?                  
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MPKIILPNFRADYSEQVRDWLGISDATASSTDTTARFLWHAEDGDVLVIPDTVDPDFPGYVADTLGIDGTSVHVERTQTP
LSEAVLQDPEFIDRLAAHTGTGAGWSLFPCVSTRAAAQLTRKLNVAALDGYEFAMQNGIDLLNMKSTFRRLAAGLGTPLT
DGVVARGPAEVRSAIQELIAETGMVIAKQDRSGGGHGNIGISTSPESSFPGTREVLAYANDQLDTLADTLWSQLTDTQNQ
FITVETYHRADQRFFFEYHLDGDRARFLHSSILKYEQLPEGSGGSAKWIGLDSPSRSEFEATLKPAEEFIEMIRTIGYRG
YVNIDGIVLDDGRVFFHEINARWSGGLIYHTVAERLLGHDYARNNFFSSILNVVPAGLADLLRSLERAGVRYDKDSGEGA
VVLGCNSDLGPGAELLVFSKDWDRLTAMKDEIATTAGTLSLEHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MPKIILPNFRADYSEQVRDWLGISDATASSTDTTARFLWHAEDGDVLVIPDTVDPDFPGYVADTLGIDGTSVHVERTQTP
LSEAVLQDPEFIDRLAAHTGTGAGWSLFPCVSTRAAAQLTRKLNVAALDGYEFAMQNGIDLLNMKSTFRRLAAGLGTPLT
DGVVARGPAEVRSAIQELIAETGMVIAKQDRSGGGHGNIGISTSPESSFPGTREVLAYANDQLDTLADTLWSQLTDTQNQ
FITVETYHRADQRFFFEYHLDGDRARFLHSSILKYEQLPEGSGGSAKWIGLDSPSRSEFEATLKPAEEFIEMIRTIGYRG
YVNIDGIVLDDGRVFFHEINARWSGGLIYHTVAERLLGHDYARNNFFSSILNVVPAGLADLLRSLERAGVRYDKDSGEGA
VVLGCNSDLGPGAELLVFSKDWDRLTAMKDEIATTAGTLSLEHHHHHH
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E,F,G,H 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PRO n 
1 3   LYS n 
1 4   ILE n 
1 5   ILE n 
1 6   LEU n 
1 7   PRO n 
1 8   ASN n 
1 9   PHE n 
1 10  ARG n 
1 11  ALA n 
1 12  ASP n 
1 13  TYR n 
1 14  SER n 
1 15  GLU n 
1 16  GLN n 
1 17  VAL n 
1 18  ARG n 
1 19  ASP n 
1 20  TRP n 
1 21  LEU n 
1 22  GLY n 
1 23  ILE n 
1 24  SER n 
1 25  ASP n 
1 26  ALA n 
1 27  THR n 
1 28  ALA n 
1 29  SER n 
1 30  SER n 
1 31  THR n 
1 32  ASP n 
1 33  THR n 
1 34  THR n 
1 35  ALA n 
1 36  ARG n 
1 37  PHE n 
1 38  LEU n 
1 39  TRP n 
1 40  HIS n 
1 41  ALA n 
1 42  GLU n 
1 43  ASP n 
1 44  GLY n 
1 45  ASP n 
1 46  VAL n 
1 47  LEU n 
1 48  VAL n 
1 49  ILE n 
1 50  PRO n 
1 51  ASP n 
1 52  THR n 
1 53  VAL n 
1 54  ASP n 
1 55  PRO n 
1 56  ASP n 
1 57  PHE n 
1 58  PRO n 
1 59  GLY n 
1 60  TYR n 
1 61  VAL n 
1 62  ALA n 
1 63  ASP n 
1 64  THR n 
1 65  LEU n 
1 66  GLY n 
1 67  ILE n 
1 68  ASP n 
1 69  GLY n 
1 70  THR n 
1 71  SER n 
1 72  VAL n 
1 73  HIS n 
1 74  VAL n 
1 75  GLU n 
1 76  ARG n 
1 77  THR n 
1 78  GLN n 
1 79  THR n 
1 80  PRO n 
1 81  LEU n 
1 82  SER n 
1 83  GLU n 
1 84  ALA n 
1 85  VAL n 
1 86  LEU n 
1 87  GLN n 
1 88  ASP n 
1 89  PRO n 
1 90  GLU n 
1 91  PHE n 
1 92  ILE n 
1 93  ASP n 
1 94  ARG n 
1 95  LEU n 
1 96  ALA n 
1 97  ALA n 
1 98  HIS n 
1 99  THR n 
1 100 GLY n 
1 101 THR n 
1 102 GLY n 
1 103 ALA n 
1 104 GLY n 
1 105 TRP n 
1 106 SER n 
1 107 LEU n 
1 108 PHE n 
1 109 PRO n 
1 110 CYS n 
1 111 VAL n 
1 112 SER n 
1 113 THR n 
1 114 ARG n 
1 115 ALA n 
1 116 ALA n 
1 117 ALA n 
1 118 GLN n 
1 119 LEU n 
1 120 THR n 
1 121 ARG n 
1 122 LYS n 
1 123 LEU n 
1 124 ASN n 
1 125 VAL n 
1 126 ALA n 
1 127 ALA n 
1 128 LEU n 
1 129 ASP n 
1 130 GLY n 
1 131 TYR n 
1 132 GLU n 
1 133 PHE n 
1 134 ALA n 
1 135 MET n 
1 136 GLN n 
1 137 ASN n 
1 138 GLY n 
1 139 ILE n 
1 140 ASP n 
1 141 LEU n 
1 142 LEU n 
1 143 ASN n 
1 144 MET n 
1 145 LYS n 
1 146 SER n 
1 147 THR n 
1 148 PHE n 
1 149 ARG n 
1 150 ARG n 
1 151 LEU n 
1 152 ALA n 
1 153 ALA n 
1 154 GLY n 
1 155 LEU n 
1 156 GLY n 
1 157 THR n 
1 158 PRO n 
1 159 LEU n 
1 160 THR n 
1 161 ASP n 
1 162 GLY n 
1 163 VAL n 
1 164 VAL n 
1 165 ALA n 
1 166 ARG n 
1 167 GLY n 
1 168 PRO n 
1 169 ALA n 
1 170 GLU n 
1 171 VAL n 
1 172 ARG n 
1 173 SER n 
1 174 ALA n 
1 175 ILE n 
1 176 GLN n 
1 177 GLU n 
1 178 LEU n 
1 179 ILE n 
1 180 ALA n 
1 181 GLU n 
1 182 THR n 
1 183 GLY n 
1 184 MET n 
1 185 VAL n 
1 186 ILE n 
1 187 ALA n 
1 188 LYS n 
1 189 GLN n 
1 190 ASP n 
1 191 ARG n 
1 192 SER n 
1 193 GLY n 
1 194 GLY n 
1 195 GLY n 
1 196 HIS n 
1 197 GLY n 
1 198 ASN n 
1 199 ILE n 
1 200 GLY n 
1 201 ILE n 
1 202 SER n 
1 203 THR n 
1 204 SER n 
1 205 PRO n 
1 206 GLU n 
1 207 SER n 
1 208 SER n 
1 209 PHE n 
1 210 PRO n 
1 211 GLY n 
1 212 THR n 
1 213 ARG n 
1 214 GLU n 
1 215 VAL n 
1 216 LEU n 
1 217 ALA n 
1 218 TYR n 
1 219 ALA n 
1 220 ASN n 
1 221 ASP n 
1 222 GLN n 
1 223 LEU n 
1 224 ASP n 
1 225 THR n 
1 226 LEU n 
1 227 ALA n 
1 228 ASP n 
1 229 THR n 
1 230 LEU n 
1 231 TRP n 
1 232 SER n 
1 233 GLN n 
1 234 LEU n 
1 235 THR n 
1 236 ASP n 
1 237 THR n 
1 238 GLN n 
1 239 ASN n 
1 240 GLN n 
1 241 PHE n 
1 242 ILE n 
1 243 THR n 
1 244 VAL n 
1 245 GLU n 
1 246 THR n 
1 247 TYR n 
1 248 HIS n 
1 249 ARG n 
1 250 ALA n 
1 251 ASP n 
1 252 GLN n 
1 253 ARG n 
1 254 PHE n 
1 255 PHE n 
1 256 PHE n 
1 257 GLU n 
1 258 TYR n 
1 259 HIS n 
1 260 LEU n 
1 261 ASP n 
1 262 GLY n 
1 263 ASP n 
1 264 ARG n 
1 265 ALA n 
1 266 ARG n 
1 267 PHE n 
1 268 LEU n 
1 269 HIS n 
1 270 SER n 
1 271 SER n 
1 272 ILE n 
1 273 LEU n 
1 274 LYS n 
1 275 TYR n 
1 276 GLU n 
1 277 GLN n 
1 278 LEU n 
1 279 PRO n 
1 280 GLU n 
1 281 GLY n 
1 282 SER n 
1 283 GLY n 
1 284 GLY n 
1 285 SER n 
1 286 ALA n 
1 287 LYS n 
1 288 TRP n 
1 289 ILE n 
1 290 GLY n 
1 291 LEU n 
1 292 ASP n 
1 293 SER n 
1 294 PRO n 
1 295 SER n 
1 296 ARG n 
1 297 SER n 
1 298 GLU n 
1 299 PHE n 
1 300 GLU n 
1 301 ALA n 
1 302 THR n 
1 303 LEU n 
1 304 LYS n 
1 305 PRO n 
1 306 ALA n 
1 307 GLU n 
1 308 GLU n 
1 309 PHE n 
1 310 ILE n 
1 311 GLU n 
1 312 MET n 
1 313 ILE n 
1 314 ARG n 
1 315 THR n 
1 316 ILE n 
1 317 GLY n 
1 318 TYR n 
1 319 ARG n 
1 320 GLY n 
1 321 TYR n 
1 322 VAL n 
1 323 ASN n 
1 324 ILE n 
1 325 ASP n 
1 326 GLY n 
1 327 ILE n 
1 328 VAL n 
1 329 LEU n 
1 330 ASP n 
1 331 ASP n 
1 332 GLY n 
1 333 ARG n 
1 334 VAL n 
1 335 PHE n 
1 336 PHE n 
1 337 HIS n 
1 338 GLU n 
1 339 ILE n 
1 340 ASN n 
1 341 ALA n 
1 342 ARG n 
1 343 TRP n 
1 344 SER n 
1 345 GLY n 
1 346 GLY n 
1 347 LEU n 
1 348 ILE n 
1 349 TYR n 
1 350 HIS n 
1 351 THR n 
1 352 VAL n 
1 353 ALA n 
1 354 GLU n 
1 355 ARG n 
1 356 LEU n 
1 357 LEU n 
1 358 GLY n 
1 359 HIS n 
1 360 ASP n 
1 361 TYR n 
1 362 ALA n 
1 363 ARG n 
1 364 ASN n 
1 365 ASN n 
1 366 PHE n 
1 367 PHE n 
1 368 SER n 
1 369 SER n 
1 370 ILE n 
1 371 LEU n 
1 372 ASN n 
1 373 VAL n 
1 374 VAL n 
1 375 PRO n 
1 376 ALA n 
1 377 GLY n 
1 378 LEU n 
1 379 ALA n 
1 380 ASP n 
1 381 LEU n 
1 382 LEU n 
1 383 ARG n 
1 384 SER n 
1 385 LEU n 
1 386 GLU n 
1 387 ARG n 
1 388 ALA n 
1 389 GLY n 
1 390 VAL n 
1 391 ARG n 
1 392 TYR n 
1 393 ASP n 
1 394 LYS n 
1 395 ASP n 
1 396 SER n 
1 397 GLY n 
1 398 GLU n 
1 399 GLY n 
1 400 ALA n 
1 401 VAL n 
1 402 VAL n 
1 403 LEU n 
1 404 GLY n 
1 405 CYS n 
1 406 ASN n 
1 407 SER n 
1 408 ASP n 
1 409 LEU n 
1 410 GLY n 
1 411 PRO n 
1 412 GLY n 
1 413 ALA n 
1 414 GLU n 
1 415 LEU n 
1 416 LEU n 
1 417 VAL n 
1 418 PHE n 
1 419 SER n 
1 420 LYS n 
1 421 ASP n 
1 422 TRP n 
1 423 ASP n 
1 424 ARG n 
1 425 LEU n 
1 426 THR n 
1 427 ALA n 
1 428 MET n 
1 429 LYS n 
1 430 ASP n 
1 431 GLU n 
1 432 ILE n 
1 433 ALA n 
1 434 THR n 
1 435 THR n 
1 436 ALA n 
1 437 GLY n 
1 438 THR n 
1 439 LEU n 
1 440 SER n 
1 441 LEU n 
1 442 GLU n 
1 443 HIS n 
1 444 HIS n 
1 445 HIS n 
1 446 HIS n 
1 447 HIS n 
1 448 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   448 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 Alb28 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Streptomyces albogriseolus 1-36' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1093098 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   PRO 2   2   2   PRO PRO A . n 
A 1 3   LYS 3   3   3   LYS LYS A . n 
A 1 4   ILE 4   4   4   ILE ILE A . n 
A 1 5   ILE 5   5   5   ILE ILE A . n 
A 1 6   LEU 6   6   6   LEU LEU A . n 
A 1 7   PRO 7   7   7   PRO PRO A . n 
A 1 8   ASN 8   8   8   ASN ASN A . n 
A 1 9   PHE 9   9   9   PHE PHE A . n 
A 1 10  ARG 10  10  ?   ?   ?   A . n 
A 1 11  ALA 11  11  ?   ?   ?   A . n 
A 1 12  ASP 12  12  ?   ?   ?   A . n 
A 1 13  TYR 13  13  ?   ?   ?   A . n 
A 1 14  SER 14  14  ?   ?   ?   A . n 
A 1 15  GLU 15  15  ?   ?   ?   A . n 
A 1 16  GLN 16  16  ?   ?   ?   A . n 
A 1 17  VAL 17  17  ?   ?   ?   A . n 
A 1 18  ARG 18  18  ?   ?   ?   A . n 
A 1 19  ASP 19  19  ?   ?   ?   A . n 
A 1 20  TRP 20  20  ?   ?   ?   A . n 
A 1 21  LEU 21  21  ?   ?   ?   A . n 
A 1 22  GLY 22  22  ?   ?   ?   A . n 
A 1 23  ILE 23  23  ?   ?   ?   A . n 
A 1 24  SER 24  24  ?   ?   ?   A . n 
A 1 25  ASP 25  25  ?   ?   ?   A . n 
A 1 26  ALA 26  26  ?   ?   ?   A . n 
A 1 27  THR 27  27  ?   ?   ?   A . n 
A 1 28  ALA 28  28  ?   ?   ?   A . n 
A 1 29  SER 29  29  ?   ?   ?   A . n 
A 1 30  SER 30  30  30  SER SER A . n 
A 1 31  THR 31  31  31  THR THR A . n 
A 1 32  ASP 32  32  32  ASP ASP A . n 
A 1 33  THR 33  33  33  THR THR A . n 
A 1 34  THR 34  34  34  THR THR A . n 
A 1 35  ALA 35  35  35  ALA ALA A . n 
A 1 36  ARG 36  36  36  ARG ARG A . n 
A 1 37  PHE 37  37  37  PHE PHE A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  TRP 39  39  39  TRP TRP A . n 
A 1 40  HIS 40  40  40  HIS HIS A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  GLU 42  42  42  GLU GLU A . n 
A 1 43  ASP 43  43  43  ASP ASP A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  ASP 45  45  45  ASP ASP A . n 
A 1 46  VAL 46  46  46  VAL VAL A . n 
A 1 47  LEU 47  47  47  LEU LEU A . n 
A 1 48  VAL 48  48  48  VAL VAL A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  PRO 50  50  50  PRO PRO A . n 
A 1 51  ASP 51  51  51  ASP ASP A . n 
A 1 52  THR 52  52  52  THR THR A . n 
A 1 53  VAL 53  53  53  VAL VAL A . n 
A 1 54  ASP 54  54  54  ASP ASP A . n 
A 1 55  PRO 55  55  55  PRO PRO A . n 
A 1 56  ASP 56  56  56  ASP ASP A . n 
A 1 57  PHE 57  57  57  PHE PHE A . n 
A 1 58  PRO 58  58  58  PRO PRO A . n 
A 1 59  GLY 59  59  59  GLY GLY A . n 
A 1 60  TYR 60  60  60  TYR TYR A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  ALA 62  62  62  ALA ALA A . n 
A 1 63  ASP 63  63  63  ASP ASP A . n 
A 1 64  THR 64  64  64  THR THR A . n 
A 1 65  LEU 65  65  65  LEU LEU A . n 
A 1 66  GLY 66  66  66  GLY GLY A . n 
A 1 67  ILE 67  67  67  ILE ILE A . n 
A 1 68  ASP 68  68  68  ASP ASP A . n 
A 1 69  GLY 69  69  69  GLY GLY A . n 
A 1 70  THR 70  70  70  THR THR A . n 
A 1 71  SER 71  71  71  SER SER A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  HIS 73  73  73  HIS HIS A . n 
A 1 74  VAL 74  74  74  VAL VAL A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  ARG 76  76  76  ARG ARG A . n 
A 1 77  THR 77  77  77  THR THR A . n 
A 1 78  GLN 78  78  78  GLN GLN A . n 
A 1 79  THR 79  79  79  THR THR A . n 
A 1 80  PRO 80  80  80  PRO PRO A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  SER 82  82  82  SER SER A . n 
A 1 83  GLU 83  83  83  GLU GLU A . n 
A 1 84  ALA 84  84  84  ALA ALA A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  GLN 87  87  87  GLN GLN A . n 
A 1 88  ASP 88  88  88  ASP ASP A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  PHE 91  91  91  PHE PHE A . n 
A 1 92  ILE 92  92  92  ILE ILE A . n 
A 1 93  ASP 93  93  93  ASP ASP A . n 
A 1 94  ARG 94  94  94  ARG ARG A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  ALA 96  96  96  ALA ALA A . n 
A 1 97  ALA 97  97  97  ALA ALA A . n 
A 1 98  HIS 98  98  98  HIS HIS A . n 
A 1 99  THR 99  99  99  THR THR A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 THR 101 101 101 THR THR A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 ALA 103 103 103 ALA ALA A . n 
A 1 104 GLY 104 104 104 GLY GLY A . n 
A 1 105 TRP 105 105 105 TRP TRP A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 PHE 108 108 108 PHE PHE A . n 
A 1 109 PRO 109 109 109 PRO PRO A . n 
A 1 110 CYS 110 110 110 CYS CYS A . n 
A 1 111 VAL 111 111 111 VAL VAL A . n 
A 1 112 SER 112 112 112 SER SER A . n 
A 1 113 THR 113 113 113 THR THR A . n 
A 1 114 ARG 114 114 114 ARG ARG A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 ALA 116 116 116 ALA ALA A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 GLN 118 118 118 GLN GLN A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 ARG 121 121 121 ARG ARG A . n 
A 1 122 LYS 122 122 122 LYS LYS A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 ASN 124 124 124 ASN ASN A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 ALA 126 126 126 ALA ALA A . n 
A 1 127 ALA 127 127 127 ALA ALA A . n 
A 1 128 LEU 128 128 128 LEU LEU A . n 
A 1 129 ASP 129 129 129 ASP ASP A . n 
A 1 130 GLY 130 130 130 GLY GLY A . n 
A 1 131 TYR 131 131 131 TYR TYR A . n 
A 1 132 GLU 132 132 132 GLU GLU A . n 
A 1 133 PHE 133 133 133 PHE PHE A . n 
A 1 134 ALA 134 134 134 ALA ALA A . n 
A 1 135 MET 135 135 135 MET MET A . n 
A 1 136 GLN 136 136 136 GLN GLN A . n 
A 1 137 ASN 137 137 137 ASN ASN A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 ILE 139 139 139 ILE ILE A . n 
A 1 140 ASP 140 140 140 ASP ASP A . n 
A 1 141 LEU 141 141 141 LEU LEU A . n 
A 1 142 LEU 142 142 142 LEU LEU A . n 
A 1 143 ASN 143 143 143 ASN ASN A . n 
A 1 144 MET 144 144 144 MET MET A . n 
A 1 145 LYS 145 145 145 LYS LYS A . n 
A 1 146 SER 146 146 146 SER SER A . n 
A 1 147 THR 147 147 147 THR THR A . n 
A 1 148 PHE 148 148 148 PHE PHE A . n 
A 1 149 ARG 149 149 149 ARG ARG A . n 
A 1 150 ARG 150 150 150 ARG ARG A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 ALA 152 152 152 ALA ALA A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 LEU 155 155 155 LEU LEU A . n 
A 1 156 GLY 156 156 156 GLY GLY A . n 
A 1 157 THR 157 157 157 THR THR A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 LEU 159 159 159 LEU LEU A . n 
A 1 160 THR 160 160 160 THR THR A . n 
A 1 161 ASP 161 161 161 ASP ASP A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 VAL 163 163 163 VAL VAL A . n 
A 1 164 VAL 164 164 164 VAL VAL A . n 
A 1 165 ALA 165 165 165 ALA ALA A . n 
A 1 166 ARG 166 166 166 ARG ARG A . n 
A 1 167 GLY 167 167 167 GLY GLY A . n 
A 1 168 PRO 168 168 168 PRO PRO A . n 
A 1 169 ALA 169 169 169 ALA ALA A . n 
A 1 170 GLU 170 170 170 GLU GLU A . n 
A 1 171 VAL 171 171 171 VAL VAL A . n 
A 1 172 ARG 172 172 172 ARG ARG A . n 
A 1 173 SER 173 173 173 SER SER A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 ILE 175 175 175 ILE ILE A . n 
A 1 176 GLN 176 176 176 GLN GLN A . n 
A 1 177 GLU 177 177 177 GLU GLU A . n 
A 1 178 LEU 178 178 178 LEU LEU A . n 
A 1 179 ILE 179 179 179 ILE ILE A . n 
A 1 180 ALA 180 180 180 ALA ALA A . n 
A 1 181 GLU 181 181 181 GLU GLU A . n 
A 1 182 THR 182 182 182 THR THR A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 MET 184 184 184 MET MET A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 ILE 186 186 186 ILE ILE A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 LYS 188 188 188 LYS LYS A . n 
A 1 189 GLN 189 189 189 GLN GLN A . n 
A 1 190 ASP 190 190 190 ASP ASP A . n 
A 1 191 ARG 191 191 191 ARG ARG A . n 
A 1 192 SER 192 192 192 SER SER A . n 
A 1 193 GLY 193 193 193 GLY GLY A . n 
A 1 194 GLY 194 194 194 GLY GLY A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 HIS 196 196 196 HIS HIS A . n 
A 1 197 GLY 197 197 197 GLY GLY A . n 
A 1 198 ASN 198 198 198 ASN ASN A . n 
A 1 199 ILE 199 199 199 ILE ILE A . n 
A 1 200 GLY 200 200 200 GLY GLY A . n 
A 1 201 ILE 201 201 201 ILE ILE A . n 
A 1 202 SER 202 202 202 SER SER A . n 
A 1 203 THR 203 203 203 THR THR A . n 
A 1 204 SER 204 204 204 SER SER A . n 
A 1 205 PRO 205 205 205 PRO PRO A . n 
A 1 206 GLU 206 206 206 GLU GLU A . n 
A 1 207 SER 207 207 207 SER SER A . n 
A 1 208 SER 208 208 208 SER SER A . n 
A 1 209 PHE 209 209 209 PHE PHE A . n 
A 1 210 PRO 210 210 210 PRO PRO A . n 
A 1 211 GLY 211 211 211 GLY GLY A . n 
A 1 212 THR 212 212 212 THR THR A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 GLU 214 214 214 GLU GLU A . n 
A 1 215 VAL 215 215 215 VAL VAL A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 ALA 217 217 217 ALA ALA A . n 
A 1 218 TYR 218 218 218 TYR TYR A . n 
A 1 219 ALA 219 219 219 ALA ALA A . n 
A 1 220 ASN 220 220 220 ASN ASN A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 GLN 222 222 222 GLN GLN A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 ASP 224 224 224 ASP ASP A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 LEU 226 226 226 LEU LEU A . n 
A 1 227 ALA 227 227 227 ALA ALA A . n 
A 1 228 ASP 228 228 228 ASP ASP A . n 
A 1 229 THR 229 229 229 THR THR A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 TRP 231 231 231 TRP TRP A . n 
A 1 232 SER 232 232 232 SER SER A . n 
A 1 233 GLN 233 233 233 GLN GLN A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 THR 235 235 235 THR THR A . n 
A 1 236 ASP 236 236 236 ASP ASP A . n 
A 1 237 THR 237 237 237 THR THR A . n 
A 1 238 GLN 238 238 238 GLN GLN A . n 
A 1 239 ASN 239 239 239 ASN ASN A . n 
A 1 240 GLN 240 240 240 GLN GLN A . n 
A 1 241 PHE 241 241 241 PHE PHE A . n 
A 1 242 ILE 242 242 242 ILE ILE A . n 
A 1 243 THR 243 243 243 THR THR A . n 
A 1 244 VAL 244 244 244 VAL VAL A . n 
A 1 245 GLU 245 245 245 GLU GLU A . n 
A 1 246 THR 246 246 246 THR THR A . n 
A 1 247 TYR 247 247 247 TYR TYR A . n 
A 1 248 HIS 248 248 248 HIS HIS A . n 
A 1 249 ARG 249 249 249 ARG ARG A . n 
A 1 250 ALA 250 250 250 ALA ALA A . n 
A 1 251 ASP 251 251 251 ASP ASP A . n 
A 1 252 GLN 252 252 252 GLN GLN A . n 
A 1 253 ARG 253 253 253 ARG ARG A . n 
A 1 254 PHE 254 254 254 PHE PHE A . n 
A 1 255 PHE 255 255 255 PHE PHE A . n 
A 1 256 PHE 256 256 256 PHE PHE A . n 
A 1 257 GLU 257 257 257 GLU GLU A . n 
A 1 258 TYR 258 258 258 TYR TYR A . n 
A 1 259 HIS 259 259 259 HIS HIS A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 ASP 261 261 261 ASP ASP A . n 
A 1 262 GLY 262 262 262 GLY GLY A . n 
A 1 263 ASP 263 263 263 ASP ASP A . n 
A 1 264 ARG 264 264 264 ARG ARG A . n 
A 1 265 ALA 265 265 265 ALA ALA A . n 
A 1 266 ARG 266 266 266 ARG ARG A . n 
A 1 267 PHE 267 267 267 PHE PHE A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 HIS 269 269 269 HIS HIS A . n 
A 1 270 SER 270 270 270 SER SER A . n 
A 1 271 SER 271 271 271 SER SER A . n 
A 1 272 ILE 272 272 272 ILE ILE A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 LYS 274 274 274 LYS LYS A . n 
A 1 275 TYR 275 275 275 TYR TYR A . n 
A 1 276 GLU 276 276 276 GLU GLU A . n 
A 1 277 GLN 277 277 277 GLN GLN A . n 
A 1 278 LEU 278 278 ?   ?   ?   A . n 
A 1 279 PRO 279 279 ?   ?   ?   A . n 
A 1 280 GLU 280 280 ?   ?   ?   A . n 
A 1 281 GLY 281 281 ?   ?   ?   A . n 
A 1 282 SER 282 282 ?   ?   ?   A . n 
A 1 283 GLY 283 283 ?   ?   ?   A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 SER 285 285 285 SER SER A . n 
A 1 286 ALA 286 286 286 ALA ALA A . n 
A 1 287 LYS 287 287 287 LYS LYS A . n 
A 1 288 TRP 288 288 288 TRP TRP A . n 
A 1 289 ILE 289 289 289 ILE ILE A . n 
A 1 290 GLY 290 290 290 GLY GLY A . n 
A 1 291 LEU 291 291 291 LEU LEU A . n 
A 1 292 ASP 292 292 292 ASP ASP A . n 
A 1 293 SER 293 293 293 SER SER A . n 
A 1 294 PRO 294 294 294 PRO PRO A . n 
A 1 295 SER 295 295 295 SER SER A . n 
A 1 296 ARG 296 296 296 ARG ARG A . n 
A 1 297 SER 297 297 297 SER SER A . n 
A 1 298 GLU 298 298 298 GLU GLU A . n 
A 1 299 PHE 299 299 299 PHE PHE A . n 
A 1 300 GLU 300 300 300 GLU GLU A . n 
A 1 301 ALA 301 301 301 ALA ALA A . n 
A 1 302 THR 302 302 302 THR THR A . n 
A 1 303 LEU 303 303 303 LEU LEU A . n 
A 1 304 LYS 304 304 304 LYS LYS A . n 
A 1 305 PRO 305 305 305 PRO PRO A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 GLU 307 307 307 GLU GLU A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 PHE 309 309 309 PHE PHE A . n 
A 1 310 ILE 310 310 310 ILE ILE A . n 
A 1 311 GLU 311 311 311 GLU GLU A . n 
A 1 312 MET 312 312 312 MET MET A . n 
A 1 313 ILE 313 313 313 ILE ILE A . n 
A 1 314 ARG 314 314 314 ARG ARG A . n 
A 1 315 THR 315 315 315 THR THR A . n 
A 1 316 ILE 316 316 316 ILE ILE A . n 
A 1 317 GLY 317 317 317 GLY GLY A . n 
A 1 318 TYR 318 318 318 TYR TYR A . n 
A 1 319 ARG 319 319 319 ARG ARG A . n 
A 1 320 GLY 320 320 320 GLY GLY A . n 
A 1 321 TYR 321 321 321 TYR TYR A . n 
A 1 322 VAL 322 322 322 VAL VAL A . n 
A 1 323 ASN 323 323 323 ASN ASN A . n 
A 1 324 ILE 324 324 324 ILE ILE A . n 
A 1 325 ASP 325 325 325 ASP ASP A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 VAL 328 328 328 VAL VAL A . n 
A 1 329 LEU 329 329 329 LEU LEU A . n 
A 1 330 ASP 330 330 330 ASP ASP A . n 
A 1 331 ASP 331 331 331 ASP ASP A . n 
A 1 332 GLY 332 332 332 GLY GLY A . n 
A 1 333 ARG 333 333 333 ARG ARG A . n 
A 1 334 VAL 334 334 334 VAL VAL A . n 
A 1 335 PHE 335 335 335 PHE PHE A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 HIS 337 337 337 HIS HIS A . n 
A 1 338 GLU 338 338 338 GLU GLU A . n 
A 1 339 ILE 339 339 339 ILE ILE A . n 
A 1 340 ASN 340 340 340 ASN ASN A . n 
A 1 341 ALA 341 341 341 ALA ALA A . n 
A 1 342 ARG 342 342 342 ARG ARG A . n 
A 1 343 TRP 343 343 343 TRP TRP A . n 
A 1 344 SER 344 344 344 SER SER A . n 
A 1 345 GLY 345 345 345 GLY GLY A . n 
A 1 346 GLY 346 346 346 GLY GLY A . n 
A 1 347 LEU 347 347 347 LEU LEU A . n 
A 1 348 ILE 348 348 348 ILE ILE A . n 
A 1 349 TYR 349 349 349 TYR TYR A . n 
A 1 350 HIS 350 350 350 HIS HIS A . n 
A 1 351 THR 351 351 351 THR THR A . n 
A 1 352 VAL 352 352 352 VAL VAL A . n 
A 1 353 ALA 353 353 353 ALA ALA A . n 
A 1 354 GLU 354 354 354 GLU GLU A . n 
A 1 355 ARG 355 355 355 ARG ARG A . n 
A 1 356 LEU 356 356 356 LEU LEU A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 GLY 358 358 358 GLY GLY A . n 
A 1 359 HIS 359 359 359 HIS HIS A . n 
A 1 360 ASP 360 360 360 ASP ASP A . n 
A 1 361 TYR 361 361 361 TYR TYR A . n 
A 1 362 ALA 362 362 362 ALA ALA A . n 
A 1 363 ARG 363 363 363 ARG ARG A . n 
A 1 364 ASN 364 364 364 ASN ASN A . n 
A 1 365 ASN 365 365 365 ASN ASN A . n 
A 1 366 PHE 366 366 366 PHE PHE A . n 
A 1 367 PHE 367 367 367 PHE PHE A . n 
A 1 368 SER 368 368 368 SER SER A . n 
A 1 369 SER 369 369 369 SER SER A . n 
A 1 370 ILE 370 370 370 ILE ILE A . n 
A 1 371 LEU 371 371 371 LEU LEU A . n 
A 1 372 ASN 372 372 372 ASN ASN A . n 
A 1 373 VAL 373 373 373 VAL VAL A . n 
A 1 374 VAL 374 374 374 VAL VAL A . n 
A 1 375 PRO 375 375 375 PRO PRO A . n 
A 1 376 ALA 376 376 376 ALA ALA A . n 
A 1 377 GLY 377 377 377 GLY GLY A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 ALA 379 379 379 ALA ALA A . n 
A 1 380 ASP 380 380 380 ASP ASP A . n 
A 1 381 LEU 381 381 381 LEU LEU A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 ARG 383 383 383 ARG ARG A . n 
A 1 384 SER 384 384 384 SER SER A . n 
A 1 385 LEU 385 385 385 LEU LEU A . n 
A 1 386 GLU 386 386 386 GLU GLU A . n 
A 1 387 ARG 387 387 387 ARG ARG A . n 
A 1 388 ALA 388 388 388 ALA ALA A . n 
A 1 389 GLY 389 389 389 GLY GLY A . n 
A 1 390 VAL 390 390 390 VAL VAL A . n 
A 1 391 ARG 391 391 391 ARG ARG A . n 
A 1 392 TYR 392 392 392 TYR TYR A . n 
A 1 393 ASP 393 393 393 ASP ASP A . n 
A 1 394 LYS 394 394 394 LYS LYS A . n 
A 1 395 ASP 395 395 395 ASP ASP A . n 
A 1 396 SER 396 396 396 SER SER A . n 
A 1 397 GLY 397 397 397 GLY GLY A . n 
A 1 398 GLU 398 398 398 GLU GLU A . n 
A 1 399 GLY 399 399 399 GLY GLY A . n 
A 1 400 ALA 400 400 400 ALA ALA A . n 
A 1 401 VAL 401 401 401 VAL VAL A . n 
A 1 402 VAL 402 402 402 VAL VAL A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 GLY 404 404 404 GLY GLY A . n 
A 1 405 CYS 405 405 405 CYS CYS A . n 
A 1 406 ASN 406 406 406 ASN ASN A . n 
A 1 407 SER 407 407 407 SER SER A . n 
A 1 408 ASP 408 408 408 ASP ASP A . n 
A 1 409 LEU 409 409 409 LEU LEU A . n 
A 1 410 GLY 410 410 410 GLY GLY A . n 
A 1 411 PRO 411 411 411 PRO PRO A . n 
A 1 412 GLY 412 412 412 GLY GLY A . n 
A 1 413 ALA 413 413 413 ALA ALA A . n 
A 1 414 GLU 414 414 414 GLU GLU A . n 
A 1 415 LEU 415 415 415 LEU LEU A . n 
A 1 416 LEU 416 416 416 LEU LEU A . n 
A 1 417 VAL 417 417 417 VAL VAL A . n 
A 1 418 PHE 418 418 418 PHE PHE A . n 
A 1 419 SER 419 419 419 SER SER A . n 
A 1 420 LYS 420 420 420 LYS LYS A . n 
A 1 421 ASP 421 421 421 ASP ASP A . n 
A 1 422 TRP 422 422 422 TRP TRP A . n 
A 1 423 ASP 423 423 423 ASP ASP A . n 
A 1 424 ARG 424 424 424 ARG ARG A . n 
A 1 425 LEU 425 425 425 LEU LEU A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 ALA 427 427 427 ALA ALA A . n 
A 1 428 MET 428 428 428 MET MET A . n 
A 1 429 LYS 429 429 429 LYS LYS A . n 
A 1 430 ASP 430 430 430 ASP ASP A . n 
A 1 431 GLU 431 431 431 GLU GLU A . n 
A 1 432 ILE 432 432 432 ILE ILE A . n 
A 1 433 ALA 433 433 433 ALA ALA A . n 
A 1 434 THR 434 434 434 THR THR A . n 
A 1 435 THR 435 435 435 THR THR A . n 
A 1 436 ALA 436 436 436 ALA ALA A . n 
A 1 437 GLY 437 437 437 GLY GLY A . n 
A 1 438 THR 438 438 438 THR THR A . n 
A 1 439 LEU 439 439 439 LEU LEU A . n 
A 1 440 SER 440 440 440 SER SER A . n 
A 1 441 LEU 441 441 ?   ?   ?   A . n 
A 1 442 GLU 442 442 ?   ?   ?   A . n 
A 1 443 HIS 443 443 ?   ?   ?   A . n 
A 1 444 HIS 444 444 ?   ?   ?   A . n 
A 1 445 HIS 445 445 ?   ?   ?   A . n 
A 1 446 HIS 446 446 ?   ?   ?   A . n 
A 1 447 HIS 447 447 ?   ?   ?   A . n 
A 1 448 HIS 448 448 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   PRO 2   2   2   PRO PRO B . n 
B 1 3   LYS 3   3   3   LYS LYS B . n 
B 1 4   ILE 4   4   4   ILE ILE B . n 
B 1 5   ILE 5   5   5   ILE ILE B . n 
B 1 6   LEU 6   6   6   LEU LEU B . n 
B 1 7   PRO 7   7   7   PRO PRO B . n 
B 1 8   ASN 8   8   8   ASN ASN B . n 
B 1 9   PHE 9   9   ?   ?   ?   B . n 
B 1 10  ARG 10  10  ?   ?   ?   B . n 
B 1 11  ALA 11  11  ?   ?   ?   B . n 
B 1 12  ASP 12  12  ?   ?   ?   B . n 
B 1 13  TYR 13  13  ?   ?   ?   B . n 
B 1 14  SER 14  14  ?   ?   ?   B . n 
B 1 15  GLU 15  15  ?   ?   ?   B . n 
B 1 16  GLN 16  16  ?   ?   ?   B . n 
B 1 17  VAL 17  17  ?   ?   ?   B . n 
B 1 18  ARG 18  18  ?   ?   ?   B . n 
B 1 19  ASP 19  19  ?   ?   ?   B . n 
B 1 20  TRP 20  20  ?   ?   ?   B . n 
B 1 21  LEU 21  21  ?   ?   ?   B . n 
B 1 22  GLY 22  22  ?   ?   ?   B . n 
B 1 23  ILE 23  23  ?   ?   ?   B . n 
B 1 24  SER 24  24  ?   ?   ?   B . n 
B 1 25  ASP 25  25  ?   ?   ?   B . n 
B 1 26  ALA 26  26  ?   ?   ?   B . n 
B 1 27  THR 27  27  27  THR THR B . n 
B 1 28  ALA 28  28  28  ALA ALA B . n 
B 1 29  SER 29  29  29  SER SER B . n 
B 1 30  SER 30  30  30  SER SER B . n 
B 1 31  THR 31  31  31  THR THR B . n 
B 1 32  ASP 32  32  32  ASP ASP B . n 
B 1 33  THR 33  33  33  THR THR B . n 
B 1 34  THR 34  34  34  THR THR B . n 
B 1 35  ALA 35  35  35  ALA ALA B . n 
B 1 36  ARG 36  36  36  ARG ARG B . n 
B 1 37  PHE 37  37  37  PHE PHE B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  TRP 39  39  39  TRP TRP B . n 
B 1 40  HIS 40  40  40  HIS HIS B . n 
B 1 41  ALA 41  41  41  ALA ALA B . n 
B 1 42  GLU 42  42  42  GLU GLU B . n 
B 1 43  ASP 43  43  43  ASP ASP B . n 
B 1 44  GLY 44  44  44  GLY GLY B . n 
B 1 45  ASP 45  45  45  ASP ASP B . n 
B 1 46  VAL 46  46  46  VAL VAL B . n 
B 1 47  LEU 47  47  47  LEU LEU B . n 
B 1 48  VAL 48  48  48  VAL VAL B . n 
B 1 49  ILE 49  49  49  ILE ILE B . n 
B 1 50  PRO 50  50  50  PRO PRO B . n 
B 1 51  ASP 51  51  51  ASP ASP B . n 
B 1 52  THR 52  52  52  THR THR B . n 
B 1 53  VAL 53  53  53  VAL VAL B . n 
B 1 54  ASP 54  54  54  ASP ASP B . n 
B 1 55  PRO 55  55  55  PRO PRO B . n 
B 1 56  ASP 56  56  56  ASP ASP B . n 
B 1 57  PHE 57  57  57  PHE PHE B . n 
B 1 58  PRO 58  58  58  PRO PRO B . n 
B 1 59  GLY 59  59  59  GLY GLY B . n 
B 1 60  TYR 60  60  60  TYR TYR B . n 
B 1 61  VAL 61  61  61  VAL VAL B . n 
B 1 62  ALA 62  62  62  ALA ALA B . n 
B 1 63  ASP 63  63  63  ASP ASP B . n 
B 1 64  THR 64  64  64  THR THR B . n 
B 1 65  LEU 65  65  65  LEU LEU B . n 
B 1 66  GLY 66  66  66  GLY GLY B . n 
B 1 67  ILE 67  67  67  ILE ILE B . n 
B 1 68  ASP 68  68  68  ASP ASP B . n 
B 1 69  GLY 69  69  69  GLY GLY B . n 
B 1 70  THR 70  70  70  THR THR B . n 
B 1 71  SER 71  71  71  SER SER B . n 
B 1 72  VAL 72  72  72  VAL VAL B . n 
B 1 73  HIS 73  73  73  HIS HIS B . n 
B 1 74  VAL 74  74  74  VAL VAL B . n 
B 1 75  GLU 75  75  75  GLU GLU B . n 
B 1 76  ARG 76  76  76  ARG ARG B . n 
B 1 77  THR 77  77  77  THR THR B . n 
B 1 78  GLN 78  78  78  GLN GLN B . n 
B 1 79  THR 79  79  79  THR THR B . n 
B 1 80  PRO 80  80  80  PRO PRO B . n 
B 1 81  LEU 81  81  81  LEU LEU B . n 
B 1 82  SER 82  82  82  SER SER B . n 
B 1 83  GLU 83  83  83  GLU GLU B . n 
B 1 84  ALA 84  84  84  ALA ALA B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  LEU 86  86  86  LEU LEU B . n 
B 1 87  GLN 87  87  87  GLN GLN B . n 
B 1 88  ASP 88  88  88  ASP ASP B . n 
B 1 89  PRO 89  89  89  PRO PRO B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  PHE 91  91  91  PHE PHE B . n 
B 1 92  ILE 92  92  92  ILE ILE B . n 
B 1 93  ASP 93  93  93  ASP ASP B . n 
B 1 94  ARG 94  94  94  ARG ARG B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  ALA 96  96  96  ALA ALA B . n 
B 1 97  ALA 97  97  97  ALA ALA B . n 
B 1 98  HIS 98  98  98  HIS HIS B . n 
B 1 99  THR 99  99  99  THR THR B . n 
B 1 100 GLY 100 100 100 GLY GLY B . n 
B 1 101 THR 101 101 101 THR THR B . n 
B 1 102 GLY 102 102 102 GLY GLY B . n 
B 1 103 ALA 103 103 103 ALA ALA B . n 
B 1 104 GLY 104 104 104 GLY GLY B . n 
B 1 105 TRP 105 105 105 TRP TRP B . n 
B 1 106 SER 106 106 106 SER SER B . n 
B 1 107 LEU 107 107 107 LEU LEU B . n 
B 1 108 PHE 108 108 108 PHE PHE B . n 
B 1 109 PRO 109 109 109 PRO PRO B . n 
B 1 110 CYS 110 110 110 CYS CYS B . n 
B 1 111 VAL 111 111 111 VAL VAL B . n 
B 1 112 SER 112 112 112 SER SER B . n 
B 1 113 THR 113 113 113 THR THR B . n 
B 1 114 ARG 114 114 114 ARG ARG B . n 
B 1 115 ALA 115 115 115 ALA ALA B . n 
B 1 116 ALA 116 116 116 ALA ALA B . n 
B 1 117 ALA 117 117 117 ALA ALA B . n 
B 1 118 GLN 118 118 118 GLN GLN B . n 
B 1 119 LEU 119 119 119 LEU LEU B . n 
B 1 120 THR 120 120 120 THR THR B . n 
B 1 121 ARG 121 121 121 ARG ARG B . n 
B 1 122 LYS 122 122 122 LYS LYS B . n 
B 1 123 LEU 123 123 123 LEU LEU B . n 
B 1 124 ASN 124 124 124 ASN ASN B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 ALA 126 126 126 ALA ALA B . n 
B 1 127 ALA 127 127 127 ALA ALA B . n 
B 1 128 LEU 128 128 128 LEU LEU B . n 
B 1 129 ASP 129 129 129 ASP ASP B . n 
B 1 130 GLY 130 130 130 GLY GLY B . n 
B 1 131 TYR 131 131 131 TYR TYR B . n 
B 1 132 GLU 132 132 132 GLU GLU B . n 
B 1 133 PHE 133 133 133 PHE PHE B . n 
B 1 134 ALA 134 134 134 ALA ALA B . n 
B 1 135 MET 135 135 135 MET MET B . n 
B 1 136 GLN 136 136 136 GLN GLN B . n 
B 1 137 ASN 137 137 137 ASN ASN B . n 
B 1 138 GLY 138 138 138 GLY GLY B . n 
B 1 139 ILE 139 139 139 ILE ILE B . n 
B 1 140 ASP 140 140 140 ASP ASP B . n 
B 1 141 LEU 141 141 141 LEU LEU B . n 
B 1 142 LEU 142 142 142 LEU LEU B . n 
B 1 143 ASN 143 143 143 ASN ASN B . n 
B 1 144 MET 144 144 144 MET MET B . n 
B 1 145 LYS 145 145 145 LYS LYS B . n 
B 1 146 SER 146 146 146 SER SER B . n 
B 1 147 THR 147 147 147 THR THR B . n 
B 1 148 PHE 148 148 148 PHE PHE B . n 
B 1 149 ARG 149 149 149 ARG ARG B . n 
B 1 150 ARG 150 150 150 ARG ARG B . n 
B 1 151 LEU 151 151 151 LEU LEU B . n 
B 1 152 ALA 152 152 152 ALA ALA B . n 
B 1 153 ALA 153 153 153 ALA ALA B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 LEU 155 155 155 LEU LEU B . n 
B 1 156 GLY 156 156 156 GLY GLY B . n 
B 1 157 THR 157 157 157 THR THR B . n 
B 1 158 PRO 158 158 158 PRO PRO B . n 
B 1 159 LEU 159 159 159 LEU LEU B . n 
B 1 160 THR 160 160 160 THR THR B . n 
B 1 161 ASP 161 161 161 ASP ASP B . n 
B 1 162 GLY 162 162 162 GLY GLY B . n 
B 1 163 VAL 163 163 163 VAL VAL B . n 
B 1 164 VAL 164 164 164 VAL VAL B . n 
B 1 165 ALA 165 165 165 ALA ALA B . n 
B 1 166 ARG 166 166 166 ARG ARG B . n 
B 1 167 GLY 167 167 167 GLY GLY B . n 
B 1 168 PRO 168 168 168 PRO PRO B . n 
B 1 169 ALA 169 169 169 ALA ALA B . n 
B 1 170 GLU 170 170 170 GLU GLU B . n 
B 1 171 VAL 171 171 171 VAL VAL B . n 
B 1 172 ARG 172 172 172 ARG ARG B . n 
B 1 173 SER 173 173 173 SER SER B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 ILE 175 175 175 ILE ILE B . n 
B 1 176 GLN 176 176 176 GLN GLN B . n 
B 1 177 GLU 177 177 177 GLU GLU B . n 
B 1 178 LEU 178 178 178 LEU LEU B . n 
B 1 179 ILE 179 179 179 ILE ILE B . n 
B 1 180 ALA 180 180 180 ALA ALA B . n 
B 1 181 GLU 181 181 181 GLU GLU B . n 
B 1 182 THR 182 182 182 THR THR B . n 
B 1 183 GLY 183 183 183 GLY GLY B . n 
B 1 184 MET 184 184 184 MET MET B . n 
B 1 185 VAL 185 185 185 VAL VAL B . n 
B 1 186 ILE 186 186 186 ILE ILE B . n 
B 1 187 ALA 187 187 187 ALA ALA B . n 
B 1 188 LYS 188 188 188 LYS LYS B . n 
B 1 189 GLN 189 189 189 GLN GLN B . n 
B 1 190 ASP 190 190 190 ASP ASP B . n 
B 1 191 ARG 191 191 191 ARG ARG B . n 
B 1 192 SER 192 192 192 SER SER B . n 
B 1 193 GLY 193 193 193 GLY GLY B . n 
B 1 194 GLY 194 194 194 GLY GLY B . n 
B 1 195 GLY 195 195 195 GLY GLY B . n 
B 1 196 HIS 196 196 196 HIS HIS B . n 
B 1 197 GLY 197 197 197 GLY GLY B . n 
B 1 198 ASN 198 198 198 ASN ASN B . n 
B 1 199 ILE 199 199 199 ILE ILE B . n 
B 1 200 GLY 200 200 200 GLY GLY B . n 
B 1 201 ILE 201 201 201 ILE ILE B . n 
B 1 202 SER 202 202 202 SER SER B . n 
B 1 203 THR 203 203 203 THR THR B . n 
B 1 204 SER 204 204 204 SER SER B . n 
B 1 205 PRO 205 205 205 PRO PRO B . n 
B 1 206 GLU 206 206 206 GLU GLU B . n 
B 1 207 SER 207 207 207 SER SER B . n 
B 1 208 SER 208 208 208 SER SER B . n 
B 1 209 PHE 209 209 209 PHE PHE B . n 
B 1 210 PRO 210 210 210 PRO PRO B . n 
B 1 211 GLY 211 211 211 GLY GLY B . n 
B 1 212 THR 212 212 212 THR THR B . n 
B 1 213 ARG 213 213 213 ARG ARG B . n 
B 1 214 GLU 214 214 214 GLU GLU B . n 
B 1 215 VAL 215 215 215 VAL VAL B . n 
B 1 216 LEU 216 216 216 LEU LEU B . n 
B 1 217 ALA 217 217 217 ALA ALA B . n 
B 1 218 TYR 218 218 218 TYR TYR B . n 
B 1 219 ALA 219 219 219 ALA ALA B . n 
B 1 220 ASN 220 220 220 ASN ASN B . n 
B 1 221 ASP 221 221 221 ASP ASP B . n 
B 1 222 GLN 222 222 222 GLN GLN B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 ASP 224 224 224 ASP ASP B . n 
B 1 225 THR 225 225 225 THR THR B . n 
B 1 226 LEU 226 226 226 LEU LEU B . n 
B 1 227 ALA 227 227 227 ALA ALA B . n 
B 1 228 ASP 228 228 228 ASP ASP B . n 
B 1 229 THR 229 229 229 THR THR B . n 
B 1 230 LEU 230 230 230 LEU LEU B . n 
B 1 231 TRP 231 231 231 TRP TRP B . n 
B 1 232 SER 232 232 232 SER SER B . n 
B 1 233 GLN 233 233 233 GLN GLN B . n 
B 1 234 LEU 234 234 234 LEU LEU B . n 
B 1 235 THR 235 235 235 THR THR B . n 
B 1 236 ASP 236 236 236 ASP ASP B . n 
B 1 237 THR 237 237 237 THR THR B . n 
B 1 238 GLN 238 238 238 GLN GLN B . n 
B 1 239 ASN 239 239 239 ASN ASN B . n 
B 1 240 GLN 240 240 240 GLN GLN B . n 
B 1 241 PHE 241 241 241 PHE PHE B . n 
B 1 242 ILE 242 242 242 ILE ILE B . n 
B 1 243 THR 243 243 243 THR THR B . n 
B 1 244 VAL 244 244 244 VAL VAL B . n 
B 1 245 GLU 245 245 245 GLU GLU B . n 
B 1 246 THR 246 246 246 THR THR B . n 
B 1 247 TYR 247 247 247 TYR TYR B . n 
B 1 248 HIS 248 248 248 HIS HIS B . n 
B 1 249 ARG 249 249 249 ARG ARG B . n 
B 1 250 ALA 250 250 250 ALA ALA B . n 
B 1 251 ASP 251 251 251 ASP ASP B . n 
B 1 252 GLN 252 252 252 GLN GLN B . n 
B 1 253 ARG 253 253 253 ARG ARG B . n 
B 1 254 PHE 254 254 254 PHE PHE B . n 
B 1 255 PHE 255 255 255 PHE PHE B . n 
B 1 256 PHE 256 256 256 PHE PHE B . n 
B 1 257 GLU 257 257 257 GLU GLU B . n 
B 1 258 TYR 258 258 258 TYR TYR B . n 
B 1 259 HIS 259 259 259 HIS HIS B . n 
B 1 260 LEU 260 260 260 LEU LEU B . n 
B 1 261 ASP 261 261 261 ASP ASP B . n 
B 1 262 GLY 262 262 262 GLY GLY B . n 
B 1 263 ASP 263 263 263 ASP ASP B . n 
B 1 264 ARG 264 264 264 ARG ARG B . n 
B 1 265 ALA 265 265 265 ALA ALA B . n 
B 1 266 ARG 266 266 266 ARG ARG B . n 
B 1 267 PHE 267 267 267 PHE PHE B . n 
B 1 268 LEU 268 268 268 LEU LEU B . n 
B 1 269 HIS 269 269 269 HIS HIS B . n 
B 1 270 SER 270 270 270 SER SER B . n 
B 1 271 SER 271 271 271 SER SER B . n 
B 1 272 ILE 272 272 272 ILE ILE B . n 
B 1 273 LEU 273 273 273 LEU LEU B . n 
B 1 274 LYS 274 274 274 LYS LYS B . n 
B 1 275 TYR 275 275 275 TYR TYR B . n 
B 1 276 GLU 276 276 276 GLU GLU B . n 
B 1 277 GLN 277 277 ?   ?   ?   B . n 
B 1 278 LEU 278 278 ?   ?   ?   B . n 
B 1 279 PRO 279 279 ?   ?   ?   B . n 
B 1 280 GLU 280 280 ?   ?   ?   B . n 
B 1 281 GLY 281 281 ?   ?   ?   B . n 
B 1 282 SER 282 282 ?   ?   ?   B . n 
B 1 283 GLY 283 283 ?   ?   ?   B . n 
B 1 284 GLY 284 284 ?   ?   ?   B . n 
B 1 285 SER 285 285 285 SER SER B . n 
B 1 286 ALA 286 286 286 ALA ALA B . n 
B 1 287 LYS 287 287 287 LYS LYS B . n 
B 1 288 TRP 288 288 288 TRP TRP B . n 
B 1 289 ILE 289 289 289 ILE ILE B . n 
B 1 290 GLY 290 290 290 GLY GLY B . n 
B 1 291 LEU 291 291 291 LEU LEU B . n 
B 1 292 ASP 292 292 292 ASP ASP B . n 
B 1 293 SER 293 293 293 SER SER B . n 
B 1 294 PRO 294 294 294 PRO PRO B . n 
B 1 295 SER 295 295 295 SER SER B . n 
B 1 296 ARG 296 296 296 ARG ARG B . n 
B 1 297 SER 297 297 297 SER SER B . n 
B 1 298 GLU 298 298 298 GLU GLU B . n 
B 1 299 PHE 299 299 299 PHE PHE B . n 
B 1 300 GLU 300 300 300 GLU GLU B . n 
B 1 301 ALA 301 301 301 ALA ALA B . n 
B 1 302 THR 302 302 302 THR THR B . n 
B 1 303 LEU 303 303 303 LEU LEU B . n 
B 1 304 LYS 304 304 304 LYS LYS B . n 
B 1 305 PRO 305 305 305 PRO PRO B . n 
B 1 306 ALA 306 306 306 ALA ALA B . n 
B 1 307 GLU 307 307 307 GLU GLU B . n 
B 1 308 GLU 308 308 308 GLU GLU B . n 
B 1 309 PHE 309 309 309 PHE PHE B . n 
B 1 310 ILE 310 310 310 ILE ILE B . n 
B 1 311 GLU 311 311 311 GLU GLU B . n 
B 1 312 MET 312 312 312 MET MET B . n 
B 1 313 ILE 313 313 313 ILE ILE B . n 
B 1 314 ARG 314 314 314 ARG ARG B . n 
B 1 315 THR 315 315 315 THR THR B . n 
B 1 316 ILE 316 316 316 ILE ILE B . n 
B 1 317 GLY 317 317 317 GLY GLY B . n 
B 1 318 TYR 318 318 318 TYR TYR B . n 
B 1 319 ARG 319 319 319 ARG ARG B . n 
B 1 320 GLY 320 320 320 GLY GLY B . n 
B 1 321 TYR 321 321 321 TYR TYR B . n 
B 1 322 VAL 322 322 322 VAL VAL B . n 
B 1 323 ASN 323 323 323 ASN ASN B . n 
B 1 324 ILE 324 324 324 ILE ILE B . n 
B 1 325 ASP 325 325 325 ASP ASP B . n 
B 1 326 GLY 326 326 326 GLY GLY B . n 
B 1 327 ILE 327 327 327 ILE ILE B . n 
B 1 328 VAL 328 328 328 VAL VAL B . n 
B 1 329 LEU 329 329 329 LEU LEU B . n 
B 1 330 ASP 330 330 330 ASP ASP B . n 
B 1 331 ASP 331 331 331 ASP ASP B . n 
B 1 332 GLY 332 332 332 GLY GLY B . n 
B 1 333 ARG 333 333 333 ARG ARG B . n 
B 1 334 VAL 334 334 334 VAL VAL B . n 
B 1 335 PHE 335 335 335 PHE PHE B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 HIS 337 337 337 HIS HIS B . n 
B 1 338 GLU 338 338 338 GLU GLU B . n 
B 1 339 ILE 339 339 339 ILE ILE B . n 
B 1 340 ASN 340 340 340 ASN ASN B . n 
B 1 341 ALA 341 341 341 ALA ALA B . n 
B 1 342 ARG 342 342 342 ARG ARG B . n 
B 1 343 TRP 343 343 343 TRP TRP B . n 
B 1 344 SER 344 344 344 SER SER B . n 
B 1 345 GLY 345 345 345 GLY GLY B . n 
B 1 346 GLY 346 346 346 GLY GLY B . n 
B 1 347 LEU 347 347 347 LEU LEU B . n 
B 1 348 ILE 348 348 348 ILE ILE B . n 
B 1 349 TYR 349 349 349 TYR TYR B . n 
B 1 350 HIS 350 350 350 HIS HIS B . n 
B 1 351 THR 351 351 351 THR THR B . n 
B 1 352 VAL 352 352 352 VAL VAL B . n 
B 1 353 ALA 353 353 353 ALA ALA B . n 
B 1 354 GLU 354 354 354 GLU GLU B . n 
B 1 355 ARG 355 355 355 ARG ARG B . n 
B 1 356 LEU 356 356 356 LEU LEU B . n 
B 1 357 LEU 357 357 357 LEU LEU B . n 
B 1 358 GLY 358 358 358 GLY GLY B . n 
B 1 359 HIS 359 359 359 HIS HIS B . n 
B 1 360 ASP 360 360 360 ASP ASP B . n 
B 1 361 TYR 361 361 361 TYR TYR B . n 
B 1 362 ALA 362 362 362 ALA ALA B . n 
B 1 363 ARG 363 363 363 ARG ARG B . n 
B 1 364 ASN 364 364 364 ASN ASN B . n 
B 1 365 ASN 365 365 365 ASN ASN B . n 
B 1 366 PHE 366 366 366 PHE PHE B . n 
B 1 367 PHE 367 367 367 PHE PHE B . n 
B 1 368 SER 368 368 368 SER SER B . n 
B 1 369 SER 369 369 369 SER SER B . n 
B 1 370 ILE 370 370 370 ILE ILE B . n 
B 1 371 LEU 371 371 371 LEU LEU B . n 
B 1 372 ASN 372 372 372 ASN ASN B . n 
B 1 373 VAL 373 373 373 VAL VAL B . n 
B 1 374 VAL 374 374 374 VAL VAL B . n 
B 1 375 PRO 375 375 375 PRO PRO B . n 
B 1 376 ALA 376 376 376 ALA ALA B . n 
B 1 377 GLY 377 377 377 GLY GLY B . n 
B 1 378 LEU 378 378 378 LEU LEU B . n 
B 1 379 ALA 379 379 379 ALA ALA B . n 
B 1 380 ASP 380 380 380 ASP ASP B . n 
B 1 381 LEU 381 381 381 LEU LEU B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 ARG 383 383 383 ARG ARG B . n 
B 1 384 SER 384 384 384 SER SER B . n 
B 1 385 LEU 385 385 385 LEU LEU B . n 
B 1 386 GLU 386 386 386 GLU GLU B . n 
B 1 387 ARG 387 387 387 ARG ARG B . n 
B 1 388 ALA 388 388 388 ALA ALA B . n 
B 1 389 GLY 389 389 389 GLY GLY B . n 
B 1 390 VAL 390 390 390 VAL VAL B . n 
B 1 391 ARG 391 391 391 ARG ARG B . n 
B 1 392 TYR 392 392 392 TYR TYR B . n 
B 1 393 ASP 393 393 393 ASP ASP B . n 
B 1 394 LYS 394 394 394 LYS LYS B . n 
B 1 395 ASP 395 395 395 ASP ASP B . n 
B 1 396 SER 396 396 396 SER SER B . n 
B 1 397 GLY 397 397 397 GLY GLY B . n 
B 1 398 GLU 398 398 398 GLU GLU B . n 
B 1 399 GLY 399 399 399 GLY GLY B . n 
B 1 400 ALA 400 400 400 ALA ALA B . n 
B 1 401 VAL 401 401 401 VAL VAL B . n 
B 1 402 VAL 402 402 402 VAL VAL B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 GLY 404 404 404 GLY GLY B . n 
B 1 405 CYS 405 405 405 CYS CYS B . n 
B 1 406 ASN 406 406 406 ASN ASN B . n 
B 1 407 SER 407 407 407 SER SER B . n 
B 1 408 ASP 408 408 408 ASP ASP B . n 
B 1 409 LEU 409 409 409 LEU LEU B . n 
B 1 410 GLY 410 410 410 GLY GLY B . n 
B 1 411 PRO 411 411 411 PRO PRO B . n 
B 1 412 GLY 412 412 412 GLY GLY B . n 
B 1 413 ALA 413 413 413 ALA ALA B . n 
B 1 414 GLU 414 414 414 GLU GLU B . n 
B 1 415 LEU 415 415 415 LEU LEU B . n 
B 1 416 LEU 416 416 416 LEU LEU B . n 
B 1 417 VAL 417 417 417 VAL VAL B . n 
B 1 418 PHE 418 418 418 PHE PHE B . n 
B 1 419 SER 419 419 419 SER SER B . n 
B 1 420 LYS 420 420 420 LYS LYS B . n 
B 1 421 ASP 421 421 421 ASP ASP B . n 
B 1 422 TRP 422 422 422 TRP TRP B . n 
B 1 423 ASP 423 423 423 ASP ASP B . n 
B 1 424 ARG 424 424 424 ARG ARG B . n 
B 1 425 LEU 425 425 425 LEU LEU B . n 
B 1 426 THR 426 426 426 THR THR B . n 
B 1 427 ALA 427 427 427 ALA ALA B . n 
B 1 428 MET 428 428 428 MET MET B . n 
B 1 429 LYS 429 429 429 LYS LYS B . n 
B 1 430 ASP 430 430 430 ASP ASP B . n 
B 1 431 GLU 431 431 431 GLU GLU B . n 
B 1 432 ILE 432 432 432 ILE ILE B . n 
B 1 433 ALA 433 433 433 ALA ALA B . n 
B 1 434 THR 434 434 434 THR THR B . n 
B 1 435 THR 435 435 435 THR THR B . n 
B 1 436 ALA 436 436 436 ALA ALA B . n 
B 1 437 GLY 437 437 437 GLY GLY B . n 
B 1 438 THR 438 438 438 THR THR B . n 
B 1 439 LEU 439 439 439 LEU LEU B . n 
B 1 440 SER 440 440 440 SER SER B . n 
B 1 441 LEU 441 441 ?   ?   ?   B . n 
B 1 442 GLU 442 442 ?   ?   ?   B . n 
B 1 443 HIS 443 443 ?   ?   ?   B . n 
B 1 444 HIS 444 444 ?   ?   ?   B . n 
B 1 445 HIS 445 445 ?   ?   ?   B . n 
B 1 446 HIS 446 446 ?   ?   ?   B . n 
B 1 447 HIS 447 447 ?   ?   ?   B . n 
B 1 448 HIS 448 448 ?   ?   ?   B . n 
C 1 1   MET 1   1   1   MET MET C . n 
C 1 2   PRO 2   2   2   PRO PRO C . n 
C 1 3   LYS 3   3   3   LYS LYS C . n 
C 1 4   ILE 4   4   4   ILE ILE C . n 
C 1 5   ILE 5   5   5   ILE ILE C . n 
C 1 6   LEU 6   6   6   LEU LEU C . n 
C 1 7   PRO 7   7   7   PRO PRO C . n 
C 1 8   ASN 8   8   8   ASN ASN C . n 
C 1 9   PHE 9   9   ?   ?   ?   C . n 
C 1 10  ARG 10  10  ?   ?   ?   C . n 
C 1 11  ALA 11  11  ?   ?   ?   C . n 
C 1 12  ASP 12  12  ?   ?   ?   C . n 
C 1 13  TYR 13  13  ?   ?   ?   C . n 
C 1 14  SER 14  14  ?   ?   ?   C . n 
C 1 15  GLU 15  15  ?   ?   ?   C . n 
C 1 16  GLN 16  16  ?   ?   ?   C . n 
C 1 17  VAL 17  17  ?   ?   ?   C . n 
C 1 18  ARG 18  18  ?   ?   ?   C . n 
C 1 19  ASP 19  19  ?   ?   ?   C . n 
C 1 20  TRP 20  20  ?   ?   ?   C . n 
C 1 21  LEU 21  21  ?   ?   ?   C . n 
C 1 22  GLY 22  22  ?   ?   ?   C . n 
C 1 23  ILE 23  23  ?   ?   ?   C . n 
C 1 24  SER 24  24  ?   ?   ?   C . n 
C 1 25  ASP 25  25  ?   ?   ?   C . n 
C 1 26  ALA 26  26  ?   ?   ?   C . n 
C 1 27  THR 27  27  ?   ?   ?   C . n 
C 1 28  ALA 28  28  ?   ?   ?   C . n 
C 1 29  SER 29  29  29  SER SER C . n 
C 1 30  SER 30  30  30  SER SER C . n 
C 1 31  THR 31  31  31  THR THR C . n 
C 1 32  ASP 32  32  32  ASP ASP C . n 
C 1 33  THR 33  33  33  THR THR C . n 
C 1 34  THR 34  34  34  THR THR C . n 
C 1 35  ALA 35  35  35  ALA ALA C . n 
C 1 36  ARG 36  36  36  ARG ARG C . n 
C 1 37  PHE 37  37  37  PHE PHE C . n 
C 1 38  LEU 38  38  38  LEU LEU C . n 
C 1 39  TRP 39  39  39  TRP TRP C . n 
C 1 40  HIS 40  40  40  HIS HIS C . n 
C 1 41  ALA 41  41  41  ALA ALA C . n 
C 1 42  GLU 42  42  42  GLU GLU C . n 
C 1 43  ASP 43  43  43  ASP ASP C . n 
C 1 44  GLY 44  44  44  GLY GLY C . n 
C 1 45  ASP 45  45  45  ASP ASP C . n 
C 1 46  VAL 46  46  46  VAL VAL C . n 
C 1 47  LEU 47  47  47  LEU LEU C . n 
C 1 48  VAL 48  48  48  VAL VAL C . n 
C 1 49  ILE 49  49  49  ILE ILE C . n 
C 1 50  PRO 50  50  50  PRO PRO C . n 
C 1 51  ASP 51  51  51  ASP ASP C . n 
C 1 52  THR 52  52  52  THR THR C . n 
C 1 53  VAL 53  53  53  VAL VAL C . n 
C 1 54  ASP 54  54  54  ASP ASP C . n 
C 1 55  PRO 55  55  55  PRO PRO C . n 
C 1 56  ASP 56  56  56  ASP ASP C . n 
C 1 57  PHE 57  57  57  PHE PHE C . n 
C 1 58  PRO 58  58  58  PRO PRO C . n 
C 1 59  GLY 59  59  59  GLY GLY C . n 
C 1 60  TYR 60  60  60  TYR TYR C . n 
C 1 61  VAL 61  61  61  VAL VAL C . n 
C 1 62  ALA 62  62  62  ALA ALA C . n 
C 1 63  ASP 63  63  63  ASP ASP C . n 
C 1 64  THR 64  64  64  THR THR C . n 
C 1 65  LEU 65  65  65  LEU LEU C . n 
C 1 66  GLY 66  66  66  GLY GLY C . n 
C 1 67  ILE 67  67  67  ILE ILE C . n 
C 1 68  ASP 68  68  68  ASP ASP C . n 
C 1 69  GLY 69  69  69  GLY GLY C . n 
C 1 70  THR 70  70  70  THR THR C . n 
C 1 71  SER 71  71  71  SER SER C . n 
C 1 72  VAL 72  72  72  VAL VAL C . n 
C 1 73  HIS 73  73  73  HIS HIS C . n 
C 1 74  VAL 74  74  74  VAL VAL C . n 
C 1 75  GLU 75  75  75  GLU GLU C . n 
C 1 76  ARG 76  76  76  ARG ARG C . n 
C 1 77  THR 77  77  77  THR THR C . n 
C 1 78  GLN 78  78  78  GLN GLN C . n 
C 1 79  THR 79  79  79  THR THR C . n 
C 1 80  PRO 80  80  80  PRO PRO C . n 
C 1 81  LEU 81  81  81  LEU LEU C . n 
C 1 82  SER 82  82  82  SER SER C . n 
C 1 83  GLU 83  83  83  GLU GLU C . n 
C 1 84  ALA 84  84  84  ALA ALA C . n 
C 1 85  VAL 85  85  85  VAL VAL C . n 
C 1 86  LEU 86  86  86  LEU LEU C . n 
C 1 87  GLN 87  87  87  GLN GLN C . n 
C 1 88  ASP 88  88  88  ASP ASP C . n 
C 1 89  PRO 89  89  89  PRO PRO C . n 
C 1 90  GLU 90  90  90  GLU GLU C . n 
C 1 91  PHE 91  91  91  PHE PHE C . n 
C 1 92  ILE 92  92  92  ILE ILE C . n 
C 1 93  ASP 93  93  93  ASP ASP C . n 
C 1 94  ARG 94  94  94  ARG ARG C . n 
C 1 95  LEU 95  95  95  LEU LEU C . n 
C 1 96  ALA 96  96  96  ALA ALA C . n 
C 1 97  ALA 97  97  97  ALA ALA C . n 
C 1 98  HIS 98  98  98  HIS HIS C . n 
C 1 99  THR 99  99  99  THR THR C . n 
C 1 100 GLY 100 100 100 GLY GLY C . n 
C 1 101 THR 101 101 101 THR THR C . n 
C 1 102 GLY 102 102 102 GLY GLY C . n 
C 1 103 ALA 103 103 103 ALA ALA C . n 
C 1 104 GLY 104 104 104 GLY GLY C . n 
C 1 105 TRP 105 105 105 TRP TRP C . n 
C 1 106 SER 106 106 106 SER SER C . n 
C 1 107 LEU 107 107 107 LEU LEU C . n 
C 1 108 PHE 108 108 108 PHE PHE C . n 
C 1 109 PRO 109 109 109 PRO PRO C . n 
C 1 110 CYS 110 110 110 CYS CYS C . n 
C 1 111 VAL 111 111 111 VAL VAL C . n 
C 1 112 SER 112 112 112 SER SER C . n 
C 1 113 THR 113 113 113 THR THR C . n 
C 1 114 ARG 114 114 114 ARG ARG C . n 
C 1 115 ALA 115 115 115 ALA ALA C . n 
C 1 116 ALA 116 116 116 ALA ALA C . n 
C 1 117 ALA 117 117 117 ALA ALA C . n 
C 1 118 GLN 118 118 118 GLN GLN C . n 
C 1 119 LEU 119 119 119 LEU LEU C . n 
C 1 120 THR 120 120 120 THR THR C . n 
C 1 121 ARG 121 121 121 ARG ARG C . n 
C 1 122 LYS 122 122 122 LYS LYS C . n 
C 1 123 LEU 123 123 123 LEU LEU C . n 
C 1 124 ASN 124 124 124 ASN ASN C . n 
C 1 125 VAL 125 125 125 VAL VAL C . n 
C 1 126 ALA 126 126 126 ALA ALA C . n 
C 1 127 ALA 127 127 127 ALA ALA C . n 
C 1 128 LEU 128 128 128 LEU LEU C . n 
C 1 129 ASP 129 129 129 ASP ASP C . n 
C 1 130 GLY 130 130 130 GLY GLY C . n 
C 1 131 TYR 131 131 131 TYR TYR C . n 
C 1 132 GLU 132 132 132 GLU GLU C . n 
C 1 133 PHE 133 133 133 PHE PHE C . n 
C 1 134 ALA 134 134 134 ALA ALA C . n 
C 1 135 MET 135 135 135 MET MET C . n 
C 1 136 GLN 136 136 136 GLN GLN C . n 
C 1 137 ASN 137 137 137 ASN ASN C . n 
C 1 138 GLY 138 138 138 GLY GLY C . n 
C 1 139 ILE 139 139 139 ILE ILE C . n 
C 1 140 ASP 140 140 140 ASP ASP C . n 
C 1 141 LEU 141 141 141 LEU LEU C . n 
C 1 142 LEU 142 142 142 LEU LEU C . n 
C 1 143 ASN 143 143 143 ASN ASN C . n 
C 1 144 MET 144 144 144 MET MET C . n 
C 1 145 LYS 145 145 145 LYS LYS C . n 
C 1 146 SER 146 146 146 SER SER C . n 
C 1 147 THR 147 147 147 THR THR C . n 
C 1 148 PHE 148 148 148 PHE PHE C . n 
C 1 149 ARG 149 149 149 ARG ARG C . n 
C 1 150 ARG 150 150 150 ARG ARG C . n 
C 1 151 LEU 151 151 151 LEU LEU C . n 
C 1 152 ALA 152 152 152 ALA ALA C . n 
C 1 153 ALA 153 153 153 ALA ALA C . n 
C 1 154 GLY 154 154 154 GLY GLY C . n 
C 1 155 LEU 155 155 155 LEU LEU C . n 
C 1 156 GLY 156 156 156 GLY GLY C . n 
C 1 157 THR 157 157 157 THR THR C . n 
C 1 158 PRO 158 158 158 PRO PRO C . n 
C 1 159 LEU 159 159 159 LEU LEU C . n 
C 1 160 THR 160 160 160 THR THR C . n 
C 1 161 ASP 161 161 161 ASP ASP C . n 
C 1 162 GLY 162 162 162 GLY GLY C . n 
C 1 163 VAL 163 163 163 VAL VAL C . n 
C 1 164 VAL 164 164 164 VAL VAL C . n 
C 1 165 ALA 165 165 165 ALA ALA C . n 
C 1 166 ARG 166 166 166 ARG ARG C . n 
C 1 167 GLY 167 167 167 GLY GLY C . n 
C 1 168 PRO 168 168 168 PRO PRO C . n 
C 1 169 ALA 169 169 169 ALA ALA C . n 
C 1 170 GLU 170 170 170 GLU GLU C . n 
C 1 171 VAL 171 171 171 VAL VAL C . n 
C 1 172 ARG 172 172 172 ARG ARG C . n 
C 1 173 SER 173 173 173 SER SER C . n 
C 1 174 ALA 174 174 174 ALA ALA C . n 
C 1 175 ILE 175 175 175 ILE ILE C . n 
C 1 176 GLN 176 176 176 GLN GLN C . n 
C 1 177 GLU 177 177 177 GLU GLU C . n 
C 1 178 LEU 178 178 178 LEU LEU C . n 
C 1 179 ILE 179 179 179 ILE ILE C . n 
C 1 180 ALA 180 180 180 ALA ALA C . n 
C 1 181 GLU 181 181 181 GLU GLU C . n 
C 1 182 THR 182 182 182 THR THR C . n 
C 1 183 GLY 183 183 183 GLY GLY C . n 
C 1 184 MET 184 184 184 MET MET C . n 
C 1 185 VAL 185 185 185 VAL VAL C . n 
C 1 186 ILE 186 186 186 ILE ILE C . n 
C 1 187 ALA 187 187 187 ALA ALA C . n 
C 1 188 LYS 188 188 188 LYS LYS C . n 
C 1 189 GLN 189 189 189 GLN GLN C . n 
C 1 190 ASP 190 190 190 ASP ASP C . n 
C 1 191 ARG 191 191 191 ARG ARG C . n 
C 1 192 SER 192 192 ?   ?   ?   C . n 
C 1 193 GLY 193 193 ?   ?   ?   C . n 
C 1 194 GLY 194 194 ?   ?   ?   C . n 
C 1 195 GLY 195 195 ?   ?   ?   C . n 
C 1 196 HIS 196 196 ?   ?   ?   C . n 
C 1 197 GLY 197 197 197 GLY GLY C . n 
C 1 198 ASN 198 198 198 ASN ASN C . n 
C 1 199 ILE 199 199 199 ILE ILE C . n 
C 1 200 GLY 200 200 200 GLY GLY C . n 
C 1 201 ILE 201 201 201 ILE ILE C . n 
C 1 202 SER 202 202 202 SER SER C . n 
C 1 203 THR 203 203 203 THR THR C . n 
C 1 204 SER 204 204 204 SER SER C . n 
C 1 205 PRO 205 205 205 PRO PRO C . n 
C 1 206 GLU 206 206 206 GLU GLU C . n 
C 1 207 SER 207 207 207 SER SER C . n 
C 1 208 SER 208 208 208 SER SER C . n 
C 1 209 PHE 209 209 209 PHE PHE C . n 
C 1 210 PRO 210 210 210 PRO PRO C . n 
C 1 211 GLY 211 211 211 GLY GLY C . n 
C 1 212 THR 212 212 212 THR THR C . n 
C 1 213 ARG 213 213 213 ARG ARG C . n 
C 1 214 GLU 214 214 214 GLU GLU C . n 
C 1 215 VAL 215 215 215 VAL VAL C . n 
C 1 216 LEU 216 216 216 LEU LEU C . n 
C 1 217 ALA 217 217 217 ALA ALA C . n 
C 1 218 TYR 218 218 218 TYR TYR C . n 
C 1 219 ALA 219 219 219 ALA ALA C . n 
C 1 220 ASN 220 220 220 ASN ASN C . n 
C 1 221 ASP 221 221 221 ASP ASP C . n 
C 1 222 GLN 222 222 222 GLN GLN C . n 
C 1 223 LEU 223 223 223 LEU LEU C . n 
C 1 224 ASP 224 224 224 ASP ASP C . n 
C 1 225 THR 225 225 225 THR THR C . n 
C 1 226 LEU 226 226 226 LEU LEU C . n 
C 1 227 ALA 227 227 227 ALA ALA C . n 
C 1 228 ASP 228 228 228 ASP ASP C . n 
C 1 229 THR 229 229 229 THR THR C . n 
C 1 230 LEU 230 230 230 LEU LEU C . n 
C 1 231 TRP 231 231 231 TRP TRP C . n 
C 1 232 SER 232 232 232 SER SER C . n 
C 1 233 GLN 233 233 233 GLN GLN C . n 
C 1 234 LEU 234 234 234 LEU LEU C . n 
C 1 235 THR 235 235 235 THR THR C . n 
C 1 236 ASP 236 236 236 ASP ASP C . n 
C 1 237 THR 237 237 237 THR THR C . n 
C 1 238 GLN 238 238 238 GLN GLN C . n 
C 1 239 ASN 239 239 239 ASN ASN C . n 
C 1 240 GLN 240 240 240 GLN GLN C . n 
C 1 241 PHE 241 241 241 PHE PHE C . n 
C 1 242 ILE 242 242 242 ILE ILE C . n 
C 1 243 THR 243 243 243 THR THR C . n 
C 1 244 VAL 244 244 244 VAL VAL C . n 
C 1 245 GLU 245 245 245 GLU GLU C . n 
C 1 246 THR 246 246 246 THR THR C . n 
C 1 247 TYR 247 247 247 TYR TYR C . n 
C 1 248 HIS 248 248 248 HIS HIS C . n 
C 1 249 ARG 249 249 249 ARG ARG C . n 
C 1 250 ALA 250 250 250 ALA ALA C . n 
C 1 251 ASP 251 251 251 ASP ASP C . n 
C 1 252 GLN 252 252 252 GLN GLN C . n 
C 1 253 ARG 253 253 253 ARG ARG C . n 
C 1 254 PHE 254 254 254 PHE PHE C . n 
C 1 255 PHE 255 255 255 PHE PHE C . n 
C 1 256 PHE 256 256 256 PHE PHE C . n 
C 1 257 GLU 257 257 257 GLU GLU C . n 
C 1 258 TYR 258 258 258 TYR TYR C . n 
C 1 259 HIS 259 259 259 HIS HIS C . n 
C 1 260 LEU 260 260 260 LEU LEU C . n 
C 1 261 ASP 261 261 261 ASP ASP C . n 
C 1 262 GLY 262 262 262 GLY GLY C . n 
C 1 263 ASP 263 263 263 ASP ASP C . n 
C 1 264 ARG 264 264 264 ARG ARG C . n 
C 1 265 ALA 265 265 265 ALA ALA C . n 
C 1 266 ARG 266 266 266 ARG ARG C . n 
C 1 267 PHE 267 267 267 PHE PHE C . n 
C 1 268 LEU 268 268 268 LEU LEU C . n 
C 1 269 HIS 269 269 269 HIS HIS C . n 
C 1 270 SER 270 270 270 SER SER C . n 
C 1 271 SER 271 271 271 SER SER C . n 
C 1 272 ILE 272 272 272 ILE ILE C . n 
C 1 273 LEU 273 273 273 LEU LEU C . n 
C 1 274 LYS 274 274 274 LYS LYS C . n 
C 1 275 TYR 275 275 275 TYR TYR C . n 
C 1 276 GLU 276 276 276 GLU GLU C . n 
C 1 277 GLN 277 277 ?   ?   ?   C . n 
C 1 278 LEU 278 278 ?   ?   ?   C . n 
C 1 279 PRO 279 279 ?   ?   ?   C . n 
C 1 280 GLU 280 280 ?   ?   ?   C . n 
C 1 281 GLY 281 281 ?   ?   ?   C . n 
C 1 282 SER 282 282 ?   ?   ?   C . n 
C 1 283 GLY 283 283 ?   ?   ?   C . n 
C 1 284 GLY 284 284 284 GLY GLY C . n 
C 1 285 SER 285 285 285 SER SER C . n 
C 1 286 ALA 286 286 286 ALA ALA C . n 
C 1 287 LYS 287 287 287 LYS LYS C . n 
C 1 288 TRP 288 288 288 TRP TRP C . n 
C 1 289 ILE 289 289 289 ILE ILE C . n 
C 1 290 GLY 290 290 290 GLY GLY C . n 
C 1 291 LEU 291 291 291 LEU LEU C . n 
C 1 292 ASP 292 292 292 ASP ASP C . n 
C 1 293 SER 293 293 293 SER SER C . n 
C 1 294 PRO 294 294 294 PRO PRO C . n 
C 1 295 SER 295 295 295 SER SER C . n 
C 1 296 ARG 296 296 296 ARG ARG C . n 
C 1 297 SER 297 297 297 SER SER C . n 
C 1 298 GLU 298 298 298 GLU GLU C . n 
C 1 299 PHE 299 299 299 PHE PHE C . n 
C 1 300 GLU 300 300 300 GLU GLU C . n 
C 1 301 ALA 301 301 301 ALA ALA C . n 
C 1 302 THR 302 302 302 THR THR C . n 
C 1 303 LEU 303 303 303 LEU LEU C . n 
C 1 304 LYS 304 304 304 LYS LYS C . n 
C 1 305 PRO 305 305 305 PRO PRO C . n 
C 1 306 ALA 306 306 306 ALA ALA C . n 
C 1 307 GLU 307 307 307 GLU GLU C . n 
C 1 308 GLU 308 308 308 GLU GLU C . n 
C 1 309 PHE 309 309 309 PHE PHE C . n 
C 1 310 ILE 310 310 310 ILE ILE C . n 
C 1 311 GLU 311 311 311 GLU GLU C . n 
C 1 312 MET 312 312 312 MET MET C . n 
C 1 313 ILE 313 313 313 ILE ILE C . n 
C 1 314 ARG 314 314 314 ARG ARG C . n 
C 1 315 THR 315 315 315 THR THR C . n 
C 1 316 ILE 316 316 316 ILE ILE C . n 
C 1 317 GLY 317 317 317 GLY GLY C . n 
C 1 318 TYR 318 318 318 TYR TYR C . n 
C 1 319 ARG 319 319 319 ARG ARG C . n 
C 1 320 GLY 320 320 320 GLY GLY C . n 
C 1 321 TYR 321 321 321 TYR TYR C . n 
C 1 322 VAL 322 322 322 VAL VAL C . n 
C 1 323 ASN 323 323 323 ASN ASN C . n 
C 1 324 ILE 324 324 324 ILE ILE C . n 
C 1 325 ASP 325 325 325 ASP ASP C . n 
C 1 326 GLY 326 326 326 GLY GLY C . n 
C 1 327 ILE 327 327 327 ILE ILE C . n 
C 1 328 VAL 328 328 328 VAL VAL C . n 
C 1 329 LEU 329 329 329 LEU LEU C . n 
C 1 330 ASP 330 330 330 ASP ASP C . n 
C 1 331 ASP 331 331 331 ASP ASP C . n 
C 1 332 GLY 332 332 332 GLY GLY C . n 
C 1 333 ARG 333 333 333 ARG ARG C . n 
C 1 334 VAL 334 334 334 VAL VAL C . n 
C 1 335 PHE 335 335 335 PHE PHE C . n 
C 1 336 PHE 336 336 336 PHE PHE C . n 
C 1 337 HIS 337 337 337 HIS HIS C . n 
C 1 338 GLU 338 338 338 GLU GLU C . n 
C 1 339 ILE 339 339 339 ILE ILE C . n 
C 1 340 ASN 340 340 340 ASN ASN C . n 
C 1 341 ALA 341 341 341 ALA ALA C . n 
C 1 342 ARG 342 342 342 ARG ARG C . n 
C 1 343 TRP 343 343 343 TRP TRP C . n 
C 1 344 SER 344 344 344 SER SER C . n 
C 1 345 GLY 345 345 345 GLY GLY C . n 
C 1 346 GLY 346 346 346 GLY GLY C . n 
C 1 347 LEU 347 347 347 LEU LEU C . n 
C 1 348 ILE 348 348 348 ILE ILE C . n 
C 1 349 TYR 349 349 349 TYR TYR C . n 
C 1 350 HIS 350 350 350 HIS HIS C . n 
C 1 351 THR 351 351 351 THR THR C . n 
C 1 352 VAL 352 352 352 VAL VAL C . n 
C 1 353 ALA 353 353 353 ALA ALA C . n 
C 1 354 GLU 354 354 354 GLU GLU C . n 
C 1 355 ARG 355 355 355 ARG ARG C . n 
C 1 356 LEU 356 356 356 LEU LEU C . n 
C 1 357 LEU 357 357 357 LEU LEU C . n 
C 1 358 GLY 358 358 358 GLY GLY C . n 
C 1 359 HIS 359 359 359 HIS HIS C . n 
C 1 360 ASP 360 360 360 ASP ASP C . n 
C 1 361 TYR 361 361 361 TYR TYR C . n 
C 1 362 ALA 362 362 362 ALA ALA C . n 
C 1 363 ARG 363 363 363 ARG ARG C . n 
C 1 364 ASN 364 364 364 ASN ASN C . n 
C 1 365 ASN 365 365 365 ASN ASN C . n 
C 1 366 PHE 366 366 366 PHE PHE C . n 
C 1 367 PHE 367 367 367 PHE PHE C . n 
C 1 368 SER 368 368 368 SER SER C . n 
C 1 369 SER 369 369 369 SER SER C . n 
C 1 370 ILE 370 370 370 ILE ILE C . n 
C 1 371 LEU 371 371 371 LEU LEU C . n 
C 1 372 ASN 372 372 372 ASN ASN C . n 
C 1 373 VAL 373 373 373 VAL VAL C . n 
C 1 374 VAL 374 374 374 VAL VAL C . n 
C 1 375 PRO 375 375 375 PRO PRO C . n 
C 1 376 ALA 376 376 376 ALA ALA C . n 
C 1 377 GLY 377 377 377 GLY GLY C . n 
C 1 378 LEU 378 378 378 LEU LEU C . n 
C 1 379 ALA 379 379 379 ALA ALA C . n 
C 1 380 ASP 380 380 380 ASP ASP C . n 
C 1 381 LEU 381 381 381 LEU LEU C . n 
C 1 382 LEU 382 382 382 LEU LEU C . n 
C 1 383 ARG 383 383 383 ARG ARG C . n 
C 1 384 SER 384 384 384 SER SER C . n 
C 1 385 LEU 385 385 385 LEU LEU C . n 
C 1 386 GLU 386 386 386 GLU GLU C . n 
C 1 387 ARG 387 387 387 ARG ARG C . n 
C 1 388 ALA 388 388 388 ALA ALA C . n 
C 1 389 GLY 389 389 389 GLY GLY C . n 
C 1 390 VAL 390 390 390 VAL VAL C . n 
C 1 391 ARG 391 391 391 ARG ARG C . n 
C 1 392 TYR 392 392 392 TYR TYR C . n 
C 1 393 ASP 393 393 393 ASP ASP C . n 
C 1 394 LYS 394 394 394 LYS LYS C . n 
C 1 395 ASP 395 395 395 ASP ASP C . n 
C 1 396 SER 396 396 396 SER SER C . n 
C 1 397 GLY 397 397 397 GLY GLY C . n 
C 1 398 GLU 398 398 398 GLU GLU C . n 
C 1 399 GLY 399 399 399 GLY GLY C . n 
C 1 400 ALA 400 400 400 ALA ALA C . n 
C 1 401 VAL 401 401 401 VAL VAL C . n 
C 1 402 VAL 402 402 402 VAL VAL C . n 
C 1 403 LEU 403 403 403 LEU LEU C . n 
C 1 404 GLY 404 404 404 GLY GLY C . n 
C 1 405 CYS 405 405 405 CYS CYS C . n 
C 1 406 ASN 406 406 406 ASN ASN C . n 
C 1 407 SER 407 407 407 SER SER C . n 
C 1 408 ASP 408 408 408 ASP ASP C . n 
C 1 409 LEU 409 409 409 LEU LEU C . n 
C 1 410 GLY 410 410 410 GLY GLY C . n 
C 1 411 PRO 411 411 411 PRO PRO C . n 
C 1 412 GLY 412 412 412 GLY GLY C . n 
C 1 413 ALA 413 413 413 ALA ALA C . n 
C 1 414 GLU 414 414 414 GLU GLU C . n 
C 1 415 LEU 415 415 415 LEU LEU C . n 
C 1 416 LEU 416 416 416 LEU LEU C . n 
C 1 417 VAL 417 417 417 VAL VAL C . n 
C 1 418 PHE 418 418 418 PHE PHE C . n 
C 1 419 SER 419 419 419 SER SER C . n 
C 1 420 LYS 420 420 420 LYS LYS C . n 
C 1 421 ASP 421 421 421 ASP ASP C . n 
C 1 422 TRP 422 422 422 TRP TRP C . n 
C 1 423 ASP 423 423 423 ASP ASP C . n 
C 1 424 ARG 424 424 424 ARG ARG C . n 
C 1 425 LEU 425 425 425 LEU LEU C . n 
C 1 426 THR 426 426 426 THR THR C . n 
C 1 427 ALA 427 427 427 ALA ALA C . n 
C 1 428 MET 428 428 428 MET MET C . n 
C 1 429 LYS 429 429 429 LYS LYS C . n 
C 1 430 ASP 430 430 430 ASP ASP C . n 
C 1 431 GLU 431 431 431 GLU GLU C . n 
C 1 432 ILE 432 432 432 ILE ILE C . n 
C 1 433 ALA 433 433 433 ALA ALA C . n 
C 1 434 THR 434 434 434 THR THR C . n 
C 1 435 THR 435 435 435 THR THR C . n 
C 1 436 ALA 436 436 436 ALA ALA C . n 
C 1 437 GLY 437 437 437 GLY GLY C . n 
C 1 438 THR 438 438 438 THR THR C . n 
C 1 439 LEU 439 439 439 LEU LEU C . n 
C 1 440 SER 440 440 440 SER SER C . n 
C 1 441 LEU 441 441 ?   ?   ?   C . n 
C 1 442 GLU 442 442 ?   ?   ?   C . n 
C 1 443 HIS 443 443 ?   ?   ?   C . n 
C 1 444 HIS 444 444 ?   ?   ?   C . n 
C 1 445 HIS 445 445 ?   ?   ?   C . n 
C 1 446 HIS 446 446 ?   ?   ?   C . n 
C 1 447 HIS 447 447 ?   ?   ?   C . n 
C 1 448 HIS 448 448 ?   ?   ?   C . n 
D 1 1   MET 1   1   1   MET MET D . n 
D 1 2   PRO 2   2   2   PRO PRO D . n 
D 1 3   LYS 3   3   3   LYS LYS D . n 
D 1 4   ILE 4   4   4   ILE ILE D . n 
D 1 5   ILE 5   5   5   ILE ILE D . n 
D 1 6   LEU 6   6   6   LEU LEU D . n 
D 1 7   PRO 7   7   7   PRO PRO D . n 
D 1 8   ASN 8   8   8   ASN ASN D . n 
D 1 9   PHE 9   9   9   PHE PHE D . n 
D 1 10  ARG 10  10  10  ARG ARG D . n 
D 1 11  ALA 11  11  11  ALA ALA D . n 
D 1 12  ASP 12  12  ?   ?   ?   D . n 
D 1 13  TYR 13  13  ?   ?   ?   D . n 
D 1 14  SER 14  14  ?   ?   ?   D . n 
D 1 15  GLU 15  15  ?   ?   ?   D . n 
D 1 16  GLN 16  16  ?   ?   ?   D . n 
D 1 17  VAL 17  17  ?   ?   ?   D . n 
D 1 18  ARG 18  18  ?   ?   ?   D . n 
D 1 19  ASP 19  19  ?   ?   ?   D . n 
D 1 20  TRP 20  20  ?   ?   ?   D . n 
D 1 21  LEU 21  21  ?   ?   ?   D . n 
D 1 22  GLY 22  22  ?   ?   ?   D . n 
D 1 23  ILE 23  23  ?   ?   ?   D . n 
D 1 24  SER 24  24  ?   ?   ?   D . n 
D 1 25  ASP 25  25  ?   ?   ?   D . n 
D 1 26  ALA 26  26  ?   ?   ?   D . n 
D 1 27  THR 27  27  ?   ?   ?   D . n 
D 1 28  ALA 28  28  ?   ?   ?   D . n 
D 1 29  SER 29  29  ?   ?   ?   D . n 
D 1 30  SER 30  30  30  SER SER D . n 
D 1 31  THR 31  31  31  THR THR D . n 
D 1 32  ASP 32  32  32  ASP ASP D . n 
D 1 33  THR 33  33  33  THR THR D . n 
D 1 34  THR 34  34  34  THR THR D . n 
D 1 35  ALA 35  35  35  ALA ALA D . n 
D 1 36  ARG 36  36  36  ARG ARG D . n 
D 1 37  PHE 37  37  37  PHE PHE D . n 
D 1 38  LEU 38  38  38  LEU LEU D . n 
D 1 39  TRP 39  39  39  TRP TRP D . n 
D 1 40  HIS 40  40  40  HIS HIS D . n 
D 1 41  ALA 41  41  41  ALA ALA D . n 
D 1 42  GLU 42  42  42  GLU GLU D . n 
D 1 43  ASP 43  43  43  ASP ASP D . n 
D 1 44  GLY 44  44  44  GLY GLY D . n 
D 1 45  ASP 45  45  45  ASP ASP D . n 
D 1 46  VAL 46  46  46  VAL VAL D . n 
D 1 47  LEU 47  47  47  LEU LEU D . n 
D 1 48  VAL 48  48  48  VAL VAL D . n 
D 1 49  ILE 49  49  49  ILE ILE D . n 
D 1 50  PRO 50  50  50  PRO PRO D . n 
D 1 51  ASP 51  51  51  ASP ASP D . n 
D 1 52  THR 52  52  52  THR THR D . n 
D 1 53  VAL 53  53  53  VAL VAL D . n 
D 1 54  ASP 54  54  54  ASP ASP D . n 
D 1 55  PRO 55  55  55  PRO PRO D . n 
D 1 56  ASP 56  56  56  ASP ASP D . n 
D 1 57  PHE 57  57  57  PHE PHE D . n 
D 1 58  PRO 58  58  58  PRO PRO D . n 
D 1 59  GLY 59  59  59  GLY GLY D . n 
D 1 60  TYR 60  60  60  TYR TYR D . n 
D 1 61  VAL 61  61  61  VAL VAL D . n 
D 1 62  ALA 62  62  62  ALA ALA D . n 
D 1 63  ASP 63  63  63  ASP ASP D . n 
D 1 64  THR 64  64  64  THR THR D . n 
D 1 65  LEU 65  65  65  LEU LEU D . n 
D 1 66  GLY 66  66  66  GLY GLY D . n 
D 1 67  ILE 67  67  67  ILE ILE D . n 
D 1 68  ASP 68  68  68  ASP ASP D . n 
D 1 69  GLY 69  69  69  GLY GLY D . n 
D 1 70  THR 70  70  70  THR THR D . n 
D 1 71  SER 71  71  71  SER SER D . n 
D 1 72  VAL 72  72  72  VAL VAL D . n 
D 1 73  HIS 73  73  73  HIS HIS D . n 
D 1 74  VAL 74  74  74  VAL VAL D . n 
D 1 75  GLU 75  75  75  GLU GLU D . n 
D 1 76  ARG 76  76  76  ARG ARG D . n 
D 1 77  THR 77  77  77  THR THR D . n 
D 1 78  GLN 78  78  78  GLN GLN D . n 
D 1 79  THR 79  79  79  THR THR D . n 
D 1 80  PRO 80  80  80  PRO PRO D . n 
D 1 81  LEU 81  81  81  LEU LEU D . n 
D 1 82  SER 82  82  82  SER SER D . n 
D 1 83  GLU 83  83  83  GLU GLU D . n 
D 1 84  ALA 84  84  84  ALA ALA D . n 
D 1 85  VAL 85  85  85  VAL VAL D . n 
D 1 86  LEU 86  86  86  LEU LEU D . n 
D 1 87  GLN 87  87  87  GLN GLN D . n 
D 1 88  ASP 88  88  88  ASP ASP D . n 
D 1 89  PRO 89  89  89  PRO PRO D . n 
D 1 90  GLU 90  90  90  GLU GLU D . n 
D 1 91  PHE 91  91  91  PHE PHE D . n 
D 1 92  ILE 92  92  92  ILE ILE D . n 
D 1 93  ASP 93  93  93  ASP ASP D . n 
D 1 94  ARG 94  94  94  ARG ARG D . n 
D 1 95  LEU 95  95  95  LEU LEU D . n 
D 1 96  ALA 96  96  96  ALA ALA D . n 
D 1 97  ALA 97  97  97  ALA ALA D . n 
D 1 98  HIS 98  98  98  HIS HIS D . n 
D 1 99  THR 99  99  99  THR THR D . n 
D 1 100 GLY 100 100 100 GLY GLY D . n 
D 1 101 THR 101 101 101 THR THR D . n 
D 1 102 GLY 102 102 102 GLY GLY D . n 
D 1 103 ALA 103 103 103 ALA ALA D . n 
D 1 104 GLY 104 104 104 GLY GLY D . n 
D 1 105 TRP 105 105 105 TRP TRP D . n 
D 1 106 SER 106 106 106 SER SER D . n 
D 1 107 LEU 107 107 107 LEU LEU D . n 
D 1 108 PHE 108 108 108 PHE PHE D . n 
D 1 109 PRO 109 109 109 PRO PRO D . n 
D 1 110 CYS 110 110 110 CYS CYS D . n 
D 1 111 VAL 111 111 111 VAL VAL D . n 
D 1 112 SER 112 112 112 SER SER D . n 
D 1 113 THR 113 113 113 THR THR D . n 
D 1 114 ARG 114 114 114 ARG ARG D . n 
D 1 115 ALA 115 115 115 ALA ALA D . n 
D 1 116 ALA 116 116 116 ALA ALA D . n 
D 1 117 ALA 117 117 117 ALA ALA D . n 
D 1 118 GLN 118 118 118 GLN GLN D . n 
D 1 119 LEU 119 119 119 LEU LEU D . n 
D 1 120 THR 120 120 120 THR THR D . n 
D 1 121 ARG 121 121 121 ARG ARG D . n 
D 1 122 LYS 122 122 122 LYS LYS D . n 
D 1 123 LEU 123 123 123 LEU LEU D . n 
D 1 124 ASN 124 124 124 ASN ASN D . n 
D 1 125 VAL 125 125 125 VAL VAL D . n 
D 1 126 ALA 126 126 126 ALA ALA D . n 
D 1 127 ALA 127 127 127 ALA ALA D . n 
D 1 128 LEU 128 128 128 LEU LEU D . n 
D 1 129 ASP 129 129 129 ASP ASP D . n 
D 1 130 GLY 130 130 130 GLY GLY D . n 
D 1 131 TYR 131 131 131 TYR TYR D . n 
D 1 132 GLU 132 132 132 GLU GLU D . n 
D 1 133 PHE 133 133 133 PHE PHE D . n 
D 1 134 ALA 134 134 134 ALA ALA D . n 
D 1 135 MET 135 135 135 MET MET D . n 
D 1 136 GLN 136 136 136 GLN GLN D . n 
D 1 137 ASN 137 137 137 ASN ASN D . n 
D 1 138 GLY 138 138 138 GLY GLY D . n 
D 1 139 ILE 139 139 139 ILE ILE D . n 
D 1 140 ASP 140 140 140 ASP ASP D . n 
D 1 141 LEU 141 141 141 LEU LEU D . n 
D 1 142 LEU 142 142 142 LEU LEU D . n 
D 1 143 ASN 143 143 143 ASN ASN D . n 
D 1 144 MET 144 144 144 MET MET D . n 
D 1 145 LYS 145 145 145 LYS LYS D . n 
D 1 146 SER 146 146 146 SER SER D . n 
D 1 147 THR 147 147 147 THR THR D . n 
D 1 148 PHE 148 148 148 PHE PHE D . n 
D 1 149 ARG 149 149 149 ARG ARG D . n 
D 1 150 ARG 150 150 150 ARG ARG D . n 
D 1 151 LEU 151 151 151 LEU LEU D . n 
D 1 152 ALA 152 152 152 ALA ALA D . n 
D 1 153 ALA 153 153 153 ALA ALA D . n 
D 1 154 GLY 154 154 154 GLY GLY D . n 
D 1 155 LEU 155 155 155 LEU LEU D . n 
D 1 156 GLY 156 156 156 GLY GLY D . n 
D 1 157 THR 157 157 157 THR THR D . n 
D 1 158 PRO 158 158 158 PRO PRO D . n 
D 1 159 LEU 159 159 159 LEU LEU D . n 
D 1 160 THR 160 160 160 THR THR D . n 
D 1 161 ASP 161 161 161 ASP ASP D . n 
D 1 162 GLY 162 162 162 GLY GLY D . n 
D 1 163 VAL 163 163 163 VAL VAL D . n 
D 1 164 VAL 164 164 164 VAL VAL D . n 
D 1 165 ALA 165 165 165 ALA ALA D . n 
D 1 166 ARG 166 166 166 ARG ARG D . n 
D 1 167 GLY 167 167 167 GLY GLY D . n 
D 1 168 PRO 168 168 168 PRO PRO D . n 
D 1 169 ALA 169 169 169 ALA ALA D . n 
D 1 170 GLU 170 170 170 GLU GLU D . n 
D 1 171 VAL 171 171 171 VAL VAL D . n 
D 1 172 ARG 172 172 172 ARG ARG D . n 
D 1 173 SER 173 173 173 SER SER D . n 
D 1 174 ALA 174 174 174 ALA ALA D . n 
D 1 175 ILE 175 175 175 ILE ILE D . n 
D 1 176 GLN 176 176 176 GLN GLN D . n 
D 1 177 GLU 177 177 177 GLU GLU D . n 
D 1 178 LEU 178 178 178 LEU LEU D . n 
D 1 179 ILE 179 179 179 ILE ILE D . n 
D 1 180 ALA 180 180 180 ALA ALA D . n 
D 1 181 GLU 181 181 181 GLU GLU D . n 
D 1 182 THR 182 182 182 THR THR D . n 
D 1 183 GLY 183 183 183 GLY GLY D . n 
D 1 184 MET 184 184 184 MET MET D . n 
D 1 185 VAL 185 185 185 VAL VAL D . n 
D 1 186 ILE 186 186 186 ILE ILE D . n 
D 1 187 ALA 187 187 187 ALA ALA D . n 
D 1 188 LYS 188 188 188 LYS LYS D . n 
D 1 189 GLN 189 189 189 GLN GLN D . n 
D 1 190 ASP 190 190 190 ASP ASP D . n 
D 1 191 ARG 191 191 191 ARG ARG D . n 
D 1 192 SER 192 192 192 SER SER D . n 
D 1 193 GLY 193 193 193 GLY GLY D . n 
D 1 194 GLY 194 194 194 GLY GLY D . n 
D 1 195 GLY 195 195 195 GLY GLY D . n 
D 1 196 HIS 196 196 196 HIS HIS D . n 
D 1 197 GLY 197 197 197 GLY GLY D . n 
D 1 198 ASN 198 198 198 ASN ASN D . n 
D 1 199 ILE 199 199 199 ILE ILE D . n 
D 1 200 GLY 200 200 200 GLY GLY D . n 
D 1 201 ILE 201 201 201 ILE ILE D . n 
D 1 202 SER 202 202 202 SER SER D . n 
D 1 203 THR 203 203 203 THR THR D . n 
D 1 204 SER 204 204 204 SER SER D . n 
D 1 205 PRO 205 205 205 PRO PRO D . n 
D 1 206 GLU 206 206 206 GLU GLU D . n 
D 1 207 SER 207 207 207 SER SER D . n 
D 1 208 SER 208 208 208 SER SER D . n 
D 1 209 PHE 209 209 209 PHE PHE D . n 
D 1 210 PRO 210 210 210 PRO PRO D . n 
D 1 211 GLY 211 211 211 GLY GLY D . n 
D 1 212 THR 212 212 212 THR THR D . n 
D 1 213 ARG 213 213 213 ARG ARG D . n 
D 1 214 GLU 214 214 214 GLU GLU D . n 
D 1 215 VAL 215 215 215 VAL VAL D . n 
D 1 216 LEU 216 216 216 LEU LEU D . n 
D 1 217 ALA 217 217 217 ALA ALA D . n 
D 1 218 TYR 218 218 218 TYR TYR D . n 
D 1 219 ALA 219 219 219 ALA ALA D . n 
D 1 220 ASN 220 220 220 ASN ASN D . n 
D 1 221 ASP 221 221 221 ASP ASP D . n 
D 1 222 GLN 222 222 222 GLN GLN D . n 
D 1 223 LEU 223 223 223 LEU LEU D . n 
D 1 224 ASP 224 224 224 ASP ASP D . n 
D 1 225 THR 225 225 225 THR THR D . n 
D 1 226 LEU 226 226 226 LEU LEU D . n 
D 1 227 ALA 227 227 227 ALA ALA D . n 
D 1 228 ASP 228 228 228 ASP ASP D . n 
D 1 229 THR 229 229 229 THR THR D . n 
D 1 230 LEU 230 230 230 LEU LEU D . n 
D 1 231 TRP 231 231 231 TRP TRP D . n 
D 1 232 SER 232 232 232 SER SER D . n 
D 1 233 GLN 233 233 233 GLN GLN D . n 
D 1 234 LEU 234 234 234 LEU LEU D . n 
D 1 235 THR 235 235 235 THR THR D . n 
D 1 236 ASP 236 236 236 ASP ASP D . n 
D 1 237 THR 237 237 237 THR THR D . n 
D 1 238 GLN 238 238 238 GLN GLN D . n 
D 1 239 ASN 239 239 239 ASN ASN D . n 
D 1 240 GLN 240 240 240 GLN GLN D . n 
D 1 241 PHE 241 241 241 PHE PHE D . n 
D 1 242 ILE 242 242 242 ILE ILE D . n 
D 1 243 THR 243 243 243 THR THR D . n 
D 1 244 VAL 244 244 244 VAL VAL D . n 
D 1 245 GLU 245 245 245 GLU GLU D . n 
D 1 246 THR 246 246 246 THR THR D . n 
D 1 247 TYR 247 247 247 TYR TYR D . n 
D 1 248 HIS 248 248 248 HIS HIS D . n 
D 1 249 ARG 249 249 249 ARG ARG D . n 
D 1 250 ALA 250 250 250 ALA ALA D . n 
D 1 251 ASP 251 251 251 ASP ASP D . n 
D 1 252 GLN 252 252 252 GLN GLN D . n 
D 1 253 ARG 253 253 253 ARG ARG D . n 
D 1 254 PHE 254 254 254 PHE PHE D . n 
D 1 255 PHE 255 255 255 PHE PHE D . n 
D 1 256 PHE 256 256 256 PHE PHE D . n 
D 1 257 GLU 257 257 257 GLU GLU D . n 
D 1 258 TYR 258 258 258 TYR TYR D . n 
D 1 259 HIS 259 259 259 HIS HIS D . n 
D 1 260 LEU 260 260 260 LEU LEU D . n 
D 1 261 ASP 261 261 261 ASP ASP D . n 
D 1 262 GLY 262 262 262 GLY GLY D . n 
D 1 263 ASP 263 263 263 ASP ASP D . n 
D 1 264 ARG 264 264 264 ARG ARG D . n 
D 1 265 ALA 265 265 265 ALA ALA D . n 
D 1 266 ARG 266 266 266 ARG ARG D . n 
D 1 267 PHE 267 267 267 PHE PHE D . n 
D 1 268 LEU 268 268 268 LEU LEU D . n 
D 1 269 HIS 269 269 269 HIS HIS D . n 
D 1 270 SER 270 270 270 SER SER D . n 
D 1 271 SER 271 271 271 SER SER D . n 
D 1 272 ILE 272 272 272 ILE ILE D . n 
D 1 273 LEU 273 273 273 LEU LEU D . n 
D 1 274 LYS 274 274 274 LYS LYS D . n 
D 1 275 TYR 275 275 275 TYR TYR D . n 
D 1 276 GLU 276 276 276 GLU GLU D . n 
D 1 277 GLN 277 277 277 GLN GLN D . n 
D 1 278 LEU 278 278 ?   ?   ?   D . n 
D 1 279 PRO 279 279 ?   ?   ?   D . n 
D 1 280 GLU 280 280 ?   ?   ?   D . n 
D 1 281 GLY 281 281 ?   ?   ?   D . n 
D 1 282 SER 282 282 ?   ?   ?   D . n 
D 1 283 GLY 283 283 283 GLY GLY D . n 
D 1 284 GLY 284 284 284 GLY GLY D . n 
D 1 285 SER 285 285 285 SER SER D . n 
D 1 286 ALA 286 286 286 ALA ALA D . n 
D 1 287 LYS 287 287 287 LYS LYS D . n 
D 1 288 TRP 288 288 288 TRP TRP D . n 
D 1 289 ILE 289 289 289 ILE ILE D . n 
D 1 290 GLY 290 290 290 GLY GLY D . n 
D 1 291 LEU 291 291 291 LEU LEU D . n 
D 1 292 ASP 292 292 292 ASP ASP D . n 
D 1 293 SER 293 293 293 SER SER D . n 
D 1 294 PRO 294 294 294 PRO PRO D . n 
D 1 295 SER 295 295 295 SER SER D . n 
D 1 296 ARG 296 296 296 ARG ARG D . n 
D 1 297 SER 297 297 297 SER SER D . n 
D 1 298 GLU 298 298 298 GLU GLU D . n 
D 1 299 PHE 299 299 299 PHE PHE D . n 
D 1 300 GLU 300 300 300 GLU GLU D . n 
D 1 301 ALA 301 301 301 ALA ALA D . n 
D 1 302 THR 302 302 302 THR THR D . n 
D 1 303 LEU 303 303 303 LEU LEU D . n 
D 1 304 LYS 304 304 304 LYS LYS D . n 
D 1 305 PRO 305 305 305 PRO PRO D . n 
D 1 306 ALA 306 306 306 ALA ALA D . n 
D 1 307 GLU 307 307 307 GLU GLU D . n 
D 1 308 GLU 308 308 308 GLU GLU D . n 
D 1 309 PHE 309 309 309 PHE PHE D . n 
D 1 310 ILE 310 310 310 ILE ILE D . n 
D 1 311 GLU 311 311 311 GLU GLU D . n 
D 1 312 MET 312 312 312 MET MET D . n 
D 1 313 ILE 313 313 313 ILE ILE D . n 
D 1 314 ARG 314 314 314 ARG ARG D . n 
D 1 315 THR 315 315 315 THR THR D . n 
D 1 316 ILE 316 316 316 ILE ILE D . n 
D 1 317 GLY 317 317 317 GLY GLY D . n 
D 1 318 TYR 318 318 318 TYR TYR D . n 
D 1 319 ARG 319 319 319 ARG ARG D . n 
D 1 320 GLY 320 320 320 GLY GLY D . n 
D 1 321 TYR 321 321 321 TYR TYR D . n 
D 1 322 VAL 322 322 322 VAL VAL D . n 
D 1 323 ASN 323 323 323 ASN ASN D . n 
D 1 324 ILE 324 324 324 ILE ILE D . n 
D 1 325 ASP 325 325 325 ASP ASP D . n 
D 1 326 GLY 326 326 326 GLY GLY D . n 
D 1 327 ILE 327 327 327 ILE ILE D . n 
D 1 328 VAL 328 328 328 VAL VAL D . n 
D 1 329 LEU 329 329 329 LEU LEU D . n 
D 1 330 ASP 330 330 330 ASP ASP D . n 
D 1 331 ASP 331 331 331 ASP ASP D . n 
D 1 332 GLY 332 332 332 GLY GLY D . n 
D 1 333 ARG 333 333 333 ARG ARG D . n 
D 1 334 VAL 334 334 334 VAL VAL D . n 
D 1 335 PHE 335 335 335 PHE PHE D . n 
D 1 336 PHE 336 336 336 PHE PHE D . n 
D 1 337 HIS 337 337 337 HIS HIS D . n 
D 1 338 GLU 338 338 338 GLU GLU D . n 
D 1 339 ILE 339 339 339 ILE ILE D . n 
D 1 340 ASN 340 340 340 ASN ASN D . n 
D 1 341 ALA 341 341 341 ALA ALA D . n 
D 1 342 ARG 342 342 342 ARG ARG D . n 
D 1 343 TRP 343 343 343 TRP TRP D . n 
D 1 344 SER 344 344 344 SER SER D . n 
D 1 345 GLY 345 345 345 GLY GLY D . n 
D 1 346 GLY 346 346 346 GLY GLY D . n 
D 1 347 LEU 347 347 347 LEU LEU D . n 
D 1 348 ILE 348 348 348 ILE ILE D . n 
D 1 349 TYR 349 349 349 TYR TYR D . n 
D 1 350 HIS 350 350 350 HIS HIS D . n 
D 1 351 THR 351 351 351 THR THR D . n 
D 1 352 VAL 352 352 352 VAL VAL D . n 
D 1 353 ALA 353 353 353 ALA ALA D . n 
D 1 354 GLU 354 354 354 GLU GLU D . n 
D 1 355 ARG 355 355 355 ARG ARG D . n 
D 1 356 LEU 356 356 356 LEU LEU D . n 
D 1 357 LEU 357 357 357 LEU LEU D . n 
D 1 358 GLY 358 358 358 GLY GLY D . n 
D 1 359 HIS 359 359 359 HIS HIS D . n 
D 1 360 ASP 360 360 360 ASP ASP D . n 
D 1 361 TYR 361 361 361 TYR TYR D . n 
D 1 362 ALA 362 362 362 ALA ALA D . n 
D 1 363 ARG 363 363 363 ARG ARG D . n 
D 1 364 ASN 364 364 364 ASN ASN D . n 
D 1 365 ASN 365 365 365 ASN ASN D . n 
D 1 366 PHE 366 366 366 PHE PHE D . n 
D 1 367 PHE 367 367 367 PHE PHE D . n 
D 1 368 SER 368 368 368 SER SER D . n 
D 1 369 SER 369 369 369 SER SER D . n 
D 1 370 ILE 370 370 370 ILE ILE D . n 
D 1 371 LEU 371 371 371 LEU LEU D . n 
D 1 372 ASN 372 372 372 ASN ASN D . n 
D 1 373 VAL 373 373 373 VAL VAL D . n 
D 1 374 VAL 374 374 374 VAL VAL D . n 
D 1 375 PRO 375 375 375 PRO PRO D . n 
D 1 376 ALA 376 376 376 ALA ALA D . n 
D 1 377 GLY 377 377 377 GLY GLY D . n 
D 1 378 LEU 378 378 378 LEU LEU D . n 
D 1 379 ALA 379 379 379 ALA ALA D . n 
D 1 380 ASP 380 380 380 ASP ASP D . n 
D 1 381 LEU 381 381 381 LEU LEU D . n 
D 1 382 LEU 382 382 382 LEU LEU D . n 
D 1 383 ARG 383 383 383 ARG ARG D . n 
D 1 384 SER 384 384 384 SER SER D . n 
D 1 385 LEU 385 385 385 LEU LEU D . n 
D 1 386 GLU 386 386 386 GLU GLU D . n 
D 1 387 ARG 387 387 387 ARG ARG D . n 
D 1 388 ALA 388 388 388 ALA ALA D . n 
D 1 389 GLY 389 389 389 GLY GLY D . n 
D 1 390 VAL 390 390 390 VAL VAL D . n 
D 1 391 ARG 391 391 391 ARG ARG D . n 
D 1 392 TYR 392 392 392 TYR TYR D . n 
D 1 393 ASP 393 393 393 ASP ASP D . n 
D 1 394 LYS 394 394 394 LYS LYS D . n 
D 1 395 ASP 395 395 395 ASP ASP D . n 
D 1 396 SER 396 396 396 SER SER D . n 
D 1 397 GLY 397 397 397 GLY GLY D . n 
D 1 398 GLU 398 398 398 GLU GLU D . n 
D 1 399 GLY 399 399 399 GLY GLY D . n 
D 1 400 ALA 400 400 400 ALA ALA D . n 
D 1 401 VAL 401 401 401 VAL VAL D . n 
D 1 402 VAL 402 402 402 VAL VAL D . n 
D 1 403 LEU 403 403 403 LEU LEU D . n 
D 1 404 GLY 404 404 404 GLY GLY D . n 
D 1 405 CYS 405 405 405 CYS CYS D . n 
D 1 406 ASN 406 406 406 ASN ASN D . n 
D 1 407 SER 407 407 407 SER SER D . n 
D 1 408 ASP 408 408 408 ASP ASP D . n 
D 1 409 LEU 409 409 409 LEU LEU D . n 
D 1 410 GLY 410 410 410 GLY GLY D . n 
D 1 411 PRO 411 411 411 PRO PRO D . n 
D 1 412 GLY 412 412 412 GLY GLY D . n 
D 1 413 ALA 413 413 413 ALA ALA D . n 
D 1 414 GLU 414 414 414 GLU GLU D . n 
D 1 415 LEU 415 415 415 LEU LEU D . n 
D 1 416 LEU 416 416 416 LEU LEU D . n 
D 1 417 VAL 417 417 417 VAL VAL D . n 
D 1 418 PHE 418 418 418 PHE PHE D . n 
D 1 419 SER 419 419 419 SER SER D . n 
D 1 420 LYS 420 420 420 LYS LYS D . n 
D 1 421 ASP 421 421 421 ASP ASP D . n 
D 1 422 TRP 422 422 422 TRP TRP D . n 
D 1 423 ASP 423 423 423 ASP ASP D . n 
D 1 424 ARG 424 424 424 ARG ARG D . n 
D 1 425 LEU 425 425 425 LEU LEU D . n 
D 1 426 THR 426 426 426 THR THR D . n 
D 1 427 ALA 427 427 427 ALA ALA D . n 
D 1 428 MET 428 428 428 MET MET D . n 
D 1 429 LYS 429 429 429 LYS LYS D . n 
D 1 430 ASP 430 430 430 ASP ASP D . n 
D 1 431 GLU 431 431 431 GLU GLU D . n 
D 1 432 ILE 432 432 432 ILE ILE D . n 
D 1 433 ALA 433 433 433 ALA ALA D . n 
D 1 434 THR 434 434 434 THR THR D . n 
D 1 435 THR 435 435 435 THR THR D . n 
D 1 436 ALA 436 436 436 ALA ALA D . n 
D 1 437 GLY 437 437 437 GLY GLY D . n 
D 1 438 THR 438 438 438 THR THR D . n 
D 1 439 LEU 439 439 439 LEU LEU D . n 
D 1 440 SER 440 440 440 SER SER D . n 
D 1 441 LEU 441 441 ?   ?   ?   D . n 
D 1 442 GLU 442 442 ?   ?   ?   D . n 
D 1 443 HIS 443 443 ?   ?   ?   D . n 
D 1 444 HIS 444 444 ?   ?   ?   D . n 
D 1 445 HIS 445 445 ?   ?   ?   D . n 
D 1 446 HIS 446 446 ?   ?   ?   D . n 
D 1 447 HIS 447 447 ?   ?   ?   D . n 
D 1 448 HIS 448 448 ?   ?   ?   D . n 
E 1 1   MET 1   1   ?   ?   ?   E . n 
E 1 2   PRO 2   2   2   PRO PRO E . n 
E 1 3   LYS 3   3   3   LYS LYS E . n 
E 1 4   ILE 4   4   4   ILE ILE E . n 
E 1 5   ILE 5   5   5   ILE ILE E . n 
E 1 6   LEU 6   6   6   LEU LEU E . n 
E 1 7   PRO 7   7   7   PRO PRO E . n 
E 1 8   ASN 8   8   8   ASN ASN E . n 
E 1 9   PHE 9   9   9   PHE PHE E . n 
E 1 10  ARG 10  10  10  ARG ARG E . n 
E 1 11  ALA 11  11  11  ALA ALA E . n 
E 1 12  ASP 12  12  12  ASP ASP E . n 
E 1 13  TYR 13  13  ?   ?   ?   E . n 
E 1 14  SER 14  14  ?   ?   ?   E . n 
E 1 15  GLU 15  15  ?   ?   ?   E . n 
E 1 16  GLN 16  16  ?   ?   ?   E . n 
E 1 17  VAL 17  17  ?   ?   ?   E . n 
E 1 18  ARG 18  18  ?   ?   ?   E . n 
E 1 19  ASP 19  19  ?   ?   ?   E . n 
E 1 20  TRP 20  20  ?   ?   ?   E . n 
E 1 21  LEU 21  21  ?   ?   ?   E . n 
E 1 22  GLY 22  22  ?   ?   ?   E . n 
E 1 23  ILE 23  23  ?   ?   ?   E . n 
E 1 24  SER 24  24  ?   ?   ?   E . n 
E 1 25  ASP 25  25  ?   ?   ?   E . n 
E 1 26  ALA 26  26  ?   ?   ?   E . n 
E 1 27  THR 27  27  ?   ?   ?   E . n 
E 1 28  ALA 28  28  ?   ?   ?   E . n 
E 1 29  SER 29  29  29  SER SER E . n 
E 1 30  SER 30  30  30  SER SER E . n 
E 1 31  THR 31  31  31  THR THR E . n 
E 1 32  ASP 32  32  32  ASP ASP E . n 
E 1 33  THR 33  33  33  THR THR E . n 
E 1 34  THR 34  34  34  THR THR E . n 
E 1 35  ALA 35  35  35  ALA ALA E . n 
E 1 36  ARG 36  36  36  ARG ARG E . n 
E 1 37  PHE 37  37  37  PHE PHE E . n 
E 1 38  LEU 38  38  38  LEU LEU E . n 
E 1 39  TRP 39  39  39  TRP TRP E . n 
E 1 40  HIS 40  40  40  HIS HIS E . n 
E 1 41  ALA 41  41  41  ALA ALA E . n 
E 1 42  GLU 42  42  42  GLU GLU E . n 
E 1 43  ASP 43  43  43  ASP ASP E . n 
E 1 44  GLY 44  44  44  GLY GLY E . n 
E 1 45  ASP 45  45  45  ASP ASP E . n 
E 1 46  VAL 46  46  46  VAL VAL E . n 
E 1 47  LEU 47  47  47  LEU LEU E . n 
E 1 48  VAL 48  48  48  VAL VAL E . n 
E 1 49  ILE 49  49  49  ILE ILE E . n 
E 1 50  PRO 50  50  50  PRO PRO E . n 
E 1 51  ASP 51  51  51  ASP ASP E . n 
E 1 52  THR 52  52  52  THR THR E . n 
E 1 53  VAL 53  53  53  VAL VAL E . n 
E 1 54  ASP 54  54  54  ASP ASP E . n 
E 1 55  PRO 55  55  55  PRO PRO E . n 
E 1 56  ASP 56  56  56  ASP ASP E . n 
E 1 57  PHE 57  57  57  PHE PHE E . n 
E 1 58  PRO 58  58  58  PRO PRO E . n 
E 1 59  GLY 59  59  59  GLY GLY E . n 
E 1 60  TYR 60  60  60  TYR TYR E . n 
E 1 61  VAL 61  61  61  VAL VAL E . n 
E 1 62  ALA 62  62  62  ALA ALA E . n 
E 1 63  ASP 63  63  63  ASP ASP E . n 
E 1 64  THR 64  64  64  THR THR E . n 
E 1 65  LEU 65  65  65  LEU LEU E . n 
E 1 66  GLY 66  66  66  GLY GLY E . n 
E 1 67  ILE 67  67  67  ILE ILE E . n 
E 1 68  ASP 68  68  68  ASP ASP E . n 
E 1 69  GLY 69  69  69  GLY GLY E . n 
E 1 70  THR 70  70  70  THR THR E . n 
E 1 71  SER 71  71  71  SER SER E . n 
E 1 72  VAL 72  72  72  VAL VAL E . n 
E 1 73  HIS 73  73  73  HIS HIS E . n 
E 1 74  VAL 74  74  74  VAL VAL E . n 
E 1 75  GLU 75  75  75  GLU GLU E . n 
E 1 76  ARG 76  76  76  ARG ARG E . n 
E 1 77  THR 77  77  77  THR THR E . n 
E 1 78  GLN 78  78  78  GLN GLN E . n 
E 1 79  THR 79  79  79  THR THR E . n 
E 1 80  PRO 80  80  80  PRO PRO E . n 
E 1 81  LEU 81  81  81  LEU LEU E . n 
E 1 82  SER 82  82  82  SER SER E . n 
E 1 83  GLU 83  83  83  GLU GLU E . n 
E 1 84  ALA 84  84  84  ALA ALA E . n 
E 1 85  VAL 85  85  85  VAL VAL E . n 
E 1 86  LEU 86  86  86  LEU LEU E . n 
E 1 87  GLN 87  87  87  GLN GLN E . n 
E 1 88  ASP 88  88  88  ASP ASP E . n 
E 1 89  PRO 89  89  89  PRO PRO E . n 
E 1 90  GLU 90  90  90  GLU GLU E . n 
E 1 91  PHE 91  91  91  PHE PHE E . n 
E 1 92  ILE 92  92  92  ILE ILE E . n 
E 1 93  ASP 93  93  93  ASP ASP E . n 
E 1 94  ARG 94  94  94  ARG ARG E . n 
E 1 95  LEU 95  95  95  LEU LEU E . n 
E 1 96  ALA 96  96  96  ALA ALA E . n 
E 1 97  ALA 97  97  97  ALA ALA E . n 
E 1 98  HIS 98  98  98  HIS HIS E . n 
E 1 99  THR 99  99  99  THR THR E . n 
E 1 100 GLY 100 100 100 GLY GLY E . n 
E 1 101 THR 101 101 101 THR THR E . n 
E 1 102 GLY 102 102 102 GLY GLY E . n 
E 1 103 ALA 103 103 103 ALA ALA E . n 
E 1 104 GLY 104 104 104 GLY GLY E . n 
E 1 105 TRP 105 105 105 TRP TRP E . n 
E 1 106 SER 106 106 106 SER SER E . n 
E 1 107 LEU 107 107 107 LEU LEU E . n 
E 1 108 PHE 108 108 108 PHE PHE E . n 
E 1 109 PRO 109 109 109 PRO PRO E . n 
E 1 110 CYS 110 110 110 CYS CYS E . n 
E 1 111 VAL 111 111 111 VAL VAL E . n 
E 1 112 SER 112 112 112 SER SER E . n 
E 1 113 THR 113 113 113 THR THR E . n 
E 1 114 ARG 114 114 114 ARG ARG E . n 
E 1 115 ALA 115 115 115 ALA ALA E . n 
E 1 116 ALA 116 116 116 ALA ALA E . n 
E 1 117 ALA 117 117 117 ALA ALA E . n 
E 1 118 GLN 118 118 118 GLN GLN E . n 
E 1 119 LEU 119 119 119 LEU LEU E . n 
E 1 120 THR 120 120 120 THR THR E . n 
E 1 121 ARG 121 121 121 ARG ARG E . n 
E 1 122 LYS 122 122 122 LYS LYS E . n 
E 1 123 LEU 123 123 123 LEU LEU E . n 
E 1 124 ASN 124 124 124 ASN ASN E . n 
E 1 125 VAL 125 125 125 VAL VAL E . n 
E 1 126 ALA 126 126 126 ALA ALA E . n 
E 1 127 ALA 127 127 127 ALA ALA E . n 
E 1 128 LEU 128 128 128 LEU LEU E . n 
E 1 129 ASP 129 129 129 ASP ASP E . n 
E 1 130 GLY 130 130 130 GLY GLY E . n 
E 1 131 TYR 131 131 131 TYR TYR E . n 
E 1 132 GLU 132 132 132 GLU GLU E . n 
E 1 133 PHE 133 133 133 PHE PHE E . n 
E 1 134 ALA 134 134 134 ALA ALA E . n 
E 1 135 MET 135 135 135 MET MET E . n 
E 1 136 GLN 136 136 136 GLN GLN E . n 
E 1 137 ASN 137 137 137 ASN ASN E . n 
E 1 138 GLY 138 138 138 GLY GLY E . n 
E 1 139 ILE 139 139 139 ILE ILE E . n 
E 1 140 ASP 140 140 140 ASP ASP E . n 
E 1 141 LEU 141 141 141 LEU LEU E . n 
E 1 142 LEU 142 142 142 LEU LEU E . n 
E 1 143 ASN 143 143 143 ASN ASN E . n 
E 1 144 MET 144 144 144 MET MET E . n 
E 1 145 LYS 145 145 145 LYS LYS E . n 
E 1 146 SER 146 146 146 SER SER E . n 
E 1 147 THR 147 147 147 THR THR E . n 
E 1 148 PHE 148 148 148 PHE PHE E . n 
E 1 149 ARG 149 149 149 ARG ARG E . n 
E 1 150 ARG 150 150 150 ARG ARG E . n 
E 1 151 LEU 151 151 151 LEU LEU E . n 
E 1 152 ALA 152 152 152 ALA ALA E . n 
E 1 153 ALA 153 153 153 ALA ALA E . n 
E 1 154 GLY 154 154 154 GLY GLY E . n 
E 1 155 LEU 155 155 155 LEU LEU E . n 
E 1 156 GLY 156 156 156 GLY GLY E . n 
E 1 157 THR 157 157 157 THR THR E . n 
E 1 158 PRO 158 158 158 PRO PRO E . n 
E 1 159 LEU 159 159 159 LEU LEU E . n 
E 1 160 THR 160 160 160 THR THR E . n 
E 1 161 ASP 161 161 161 ASP ASP E . n 
E 1 162 GLY 162 162 162 GLY GLY E . n 
E 1 163 VAL 163 163 163 VAL VAL E . n 
E 1 164 VAL 164 164 164 VAL VAL E . n 
E 1 165 ALA 165 165 165 ALA ALA E . n 
E 1 166 ARG 166 166 166 ARG ARG E . n 
E 1 167 GLY 167 167 167 GLY GLY E . n 
E 1 168 PRO 168 168 168 PRO PRO E . n 
E 1 169 ALA 169 169 169 ALA ALA E . n 
E 1 170 GLU 170 170 170 GLU GLU E . n 
E 1 171 VAL 171 171 171 VAL VAL E . n 
E 1 172 ARG 172 172 172 ARG ARG E . n 
E 1 173 SER 173 173 173 SER SER E . n 
E 1 174 ALA 174 174 174 ALA ALA E . n 
E 1 175 ILE 175 175 175 ILE ILE E . n 
E 1 176 GLN 176 176 176 GLN GLN E . n 
E 1 177 GLU 177 177 177 GLU GLU E . n 
E 1 178 LEU 178 178 178 LEU LEU E . n 
E 1 179 ILE 179 179 179 ILE ILE E . n 
E 1 180 ALA 180 180 180 ALA ALA E . n 
E 1 181 GLU 181 181 181 GLU GLU E . n 
E 1 182 THR 182 182 182 THR THR E . n 
E 1 183 GLY 183 183 183 GLY GLY E . n 
E 1 184 MET 184 184 184 MET MET E . n 
E 1 185 VAL 185 185 185 VAL VAL E . n 
E 1 186 ILE 186 186 186 ILE ILE E . n 
E 1 187 ALA 187 187 187 ALA ALA E . n 
E 1 188 LYS 188 188 188 LYS LYS E . n 
E 1 189 GLN 189 189 189 GLN GLN E . n 
E 1 190 ASP 190 190 190 ASP ASP E . n 
E 1 191 ARG 191 191 191 ARG ARG E . n 
E 1 192 SER 192 192 192 SER SER E . n 
E 1 193 GLY 193 193 193 GLY GLY E . n 
E 1 194 GLY 194 194 194 GLY GLY E . n 
E 1 195 GLY 195 195 195 GLY GLY E . n 
E 1 196 HIS 196 196 196 HIS HIS E . n 
E 1 197 GLY 197 197 197 GLY GLY E . n 
E 1 198 ASN 198 198 198 ASN ASN E . n 
E 1 199 ILE 199 199 199 ILE ILE E . n 
E 1 200 GLY 200 200 200 GLY GLY E . n 
E 1 201 ILE 201 201 201 ILE ILE E . n 
E 1 202 SER 202 202 202 SER SER E . n 
E 1 203 THR 203 203 203 THR THR E . n 
E 1 204 SER 204 204 204 SER SER E . n 
E 1 205 PRO 205 205 205 PRO PRO E . n 
E 1 206 GLU 206 206 206 GLU GLU E . n 
E 1 207 SER 207 207 207 SER SER E . n 
E 1 208 SER 208 208 208 SER SER E . n 
E 1 209 PHE 209 209 209 PHE PHE E . n 
E 1 210 PRO 210 210 210 PRO PRO E . n 
E 1 211 GLY 211 211 211 GLY GLY E . n 
E 1 212 THR 212 212 212 THR THR E . n 
E 1 213 ARG 213 213 213 ARG ARG E . n 
E 1 214 GLU 214 214 214 GLU GLU E . n 
E 1 215 VAL 215 215 215 VAL VAL E . n 
E 1 216 LEU 216 216 216 LEU LEU E . n 
E 1 217 ALA 217 217 217 ALA ALA E . n 
E 1 218 TYR 218 218 218 TYR TYR E . n 
E 1 219 ALA 219 219 219 ALA ALA E . n 
E 1 220 ASN 220 220 220 ASN ASN E . n 
E 1 221 ASP 221 221 221 ASP ASP E . n 
E 1 222 GLN 222 222 222 GLN GLN E . n 
E 1 223 LEU 223 223 223 LEU LEU E . n 
E 1 224 ASP 224 224 224 ASP ASP E . n 
E 1 225 THR 225 225 225 THR THR E . n 
E 1 226 LEU 226 226 226 LEU LEU E . n 
E 1 227 ALA 227 227 227 ALA ALA E . n 
E 1 228 ASP 228 228 228 ASP ASP E . n 
E 1 229 THR 229 229 229 THR THR E . n 
E 1 230 LEU 230 230 230 LEU LEU E . n 
E 1 231 TRP 231 231 231 TRP TRP E . n 
E 1 232 SER 232 232 232 SER SER E . n 
E 1 233 GLN 233 233 233 GLN GLN E . n 
E 1 234 LEU 234 234 234 LEU LEU E . n 
E 1 235 THR 235 235 235 THR THR E . n 
E 1 236 ASP 236 236 236 ASP ASP E . n 
E 1 237 THR 237 237 237 THR THR E . n 
E 1 238 GLN 238 238 238 GLN GLN E . n 
E 1 239 ASN 239 239 239 ASN ASN E . n 
E 1 240 GLN 240 240 240 GLN GLN E . n 
E 1 241 PHE 241 241 241 PHE PHE E . n 
E 1 242 ILE 242 242 242 ILE ILE E . n 
E 1 243 THR 243 243 243 THR THR E . n 
E 1 244 VAL 244 244 244 VAL VAL E . n 
E 1 245 GLU 245 245 245 GLU GLU E . n 
E 1 246 THR 246 246 246 THR THR E . n 
E 1 247 TYR 247 247 247 TYR TYR E . n 
E 1 248 HIS 248 248 248 HIS HIS E . n 
E 1 249 ARG 249 249 249 ARG ARG E . n 
E 1 250 ALA 250 250 250 ALA ALA E . n 
E 1 251 ASP 251 251 251 ASP ASP E . n 
E 1 252 GLN 252 252 252 GLN GLN E . n 
E 1 253 ARG 253 253 253 ARG ARG E . n 
E 1 254 PHE 254 254 254 PHE PHE E . n 
E 1 255 PHE 255 255 255 PHE PHE E . n 
E 1 256 PHE 256 256 256 PHE PHE E . n 
E 1 257 GLU 257 257 257 GLU GLU E . n 
E 1 258 TYR 258 258 258 TYR TYR E . n 
E 1 259 HIS 259 259 259 HIS HIS E . n 
E 1 260 LEU 260 260 260 LEU LEU E . n 
E 1 261 ASP 261 261 261 ASP ASP E . n 
E 1 262 GLY 262 262 262 GLY GLY E . n 
E 1 263 ASP 263 263 263 ASP ASP E . n 
E 1 264 ARG 264 264 264 ARG ARG E . n 
E 1 265 ALA 265 265 265 ALA ALA E . n 
E 1 266 ARG 266 266 266 ARG ARG E . n 
E 1 267 PHE 267 267 267 PHE PHE E . n 
E 1 268 LEU 268 268 268 LEU LEU E . n 
E 1 269 HIS 269 269 269 HIS HIS E . n 
E 1 270 SER 270 270 270 SER SER E . n 
E 1 271 SER 271 271 271 SER SER E . n 
E 1 272 ILE 272 272 272 ILE ILE E . n 
E 1 273 LEU 273 273 273 LEU LEU E . n 
E 1 274 LYS 274 274 274 LYS LYS E . n 
E 1 275 TYR 275 275 275 TYR TYR E . n 
E 1 276 GLU 276 276 276 GLU GLU E . n 
E 1 277 GLN 277 277 ?   ?   ?   E . n 
E 1 278 LEU 278 278 ?   ?   ?   E . n 
E 1 279 PRO 279 279 ?   ?   ?   E . n 
E 1 280 GLU 280 280 ?   ?   ?   E . n 
E 1 281 GLY 281 281 ?   ?   ?   E . n 
E 1 282 SER 282 282 ?   ?   ?   E . n 
E 1 283 GLY 283 283 ?   ?   ?   E . n 
E 1 284 GLY 284 284 ?   ?   ?   E . n 
E 1 285 SER 285 285 285 SER SER E . n 
E 1 286 ALA 286 286 286 ALA ALA E . n 
E 1 287 LYS 287 287 287 LYS LYS E . n 
E 1 288 TRP 288 288 288 TRP TRP E . n 
E 1 289 ILE 289 289 289 ILE ILE E . n 
E 1 290 GLY 290 290 290 GLY GLY E . n 
E 1 291 LEU 291 291 291 LEU LEU E . n 
E 1 292 ASP 292 292 292 ASP ASP E . n 
E 1 293 SER 293 293 293 SER SER E . n 
E 1 294 PRO 294 294 294 PRO PRO E . n 
E 1 295 SER 295 295 295 SER SER E . n 
E 1 296 ARG 296 296 296 ARG ARG E . n 
E 1 297 SER 297 297 297 SER SER E . n 
E 1 298 GLU 298 298 298 GLU GLU E . n 
E 1 299 PHE 299 299 299 PHE PHE E . n 
E 1 300 GLU 300 300 300 GLU GLU E . n 
E 1 301 ALA 301 301 301 ALA ALA E . n 
E 1 302 THR 302 302 302 THR THR E . n 
E 1 303 LEU 303 303 303 LEU LEU E . n 
E 1 304 LYS 304 304 304 LYS LYS E . n 
E 1 305 PRO 305 305 305 PRO PRO E . n 
E 1 306 ALA 306 306 306 ALA ALA E . n 
E 1 307 GLU 307 307 307 GLU GLU E . n 
E 1 308 GLU 308 308 308 GLU GLU E . n 
E 1 309 PHE 309 309 309 PHE PHE E . n 
E 1 310 ILE 310 310 310 ILE ILE E . n 
E 1 311 GLU 311 311 311 GLU GLU E . n 
E 1 312 MET 312 312 312 MET MET E . n 
E 1 313 ILE 313 313 313 ILE ILE E . n 
E 1 314 ARG 314 314 314 ARG ARG E . n 
E 1 315 THR 315 315 315 THR THR E . n 
E 1 316 ILE 316 316 316 ILE ILE E . n 
E 1 317 GLY 317 317 317 GLY GLY E . n 
E 1 318 TYR 318 318 318 TYR TYR E . n 
E 1 319 ARG 319 319 319 ARG ARG E . n 
E 1 320 GLY 320 320 320 GLY GLY E . n 
E 1 321 TYR 321 321 321 TYR TYR E . n 
E 1 322 VAL 322 322 322 VAL VAL E . n 
E 1 323 ASN 323 323 323 ASN ASN E . n 
E 1 324 ILE 324 324 324 ILE ILE E . n 
E 1 325 ASP 325 325 325 ASP ASP E . n 
E 1 326 GLY 326 326 326 GLY GLY E . n 
E 1 327 ILE 327 327 327 ILE ILE E . n 
E 1 328 VAL 328 328 328 VAL VAL E . n 
E 1 329 LEU 329 329 329 LEU LEU E . n 
E 1 330 ASP 330 330 330 ASP ASP E . n 
E 1 331 ASP 331 331 331 ASP ASP E . n 
E 1 332 GLY 332 332 332 GLY GLY E . n 
E 1 333 ARG 333 333 333 ARG ARG E . n 
E 1 334 VAL 334 334 334 VAL VAL E . n 
E 1 335 PHE 335 335 335 PHE PHE E . n 
E 1 336 PHE 336 336 336 PHE PHE E . n 
E 1 337 HIS 337 337 337 HIS HIS E . n 
E 1 338 GLU 338 338 338 GLU GLU E . n 
E 1 339 ILE 339 339 339 ILE ILE E . n 
E 1 340 ASN 340 340 340 ASN ASN E . n 
E 1 341 ALA 341 341 341 ALA ALA E . n 
E 1 342 ARG 342 342 342 ARG ARG E . n 
E 1 343 TRP 343 343 343 TRP TRP E . n 
E 1 344 SER 344 344 344 SER SER E . n 
E 1 345 GLY 345 345 345 GLY GLY E . n 
E 1 346 GLY 346 346 346 GLY GLY E . n 
E 1 347 LEU 347 347 347 LEU LEU E . n 
E 1 348 ILE 348 348 348 ILE ILE E . n 
E 1 349 TYR 349 349 349 TYR TYR E . n 
E 1 350 HIS 350 350 350 HIS HIS E . n 
E 1 351 THR 351 351 351 THR THR E . n 
E 1 352 VAL 352 352 352 VAL VAL E . n 
E 1 353 ALA 353 353 353 ALA ALA E . n 
E 1 354 GLU 354 354 354 GLU GLU E . n 
E 1 355 ARG 355 355 355 ARG ARG E . n 
E 1 356 LEU 356 356 356 LEU LEU E . n 
E 1 357 LEU 357 357 357 LEU LEU E . n 
E 1 358 GLY 358 358 358 GLY GLY E . n 
E 1 359 HIS 359 359 359 HIS HIS E . n 
E 1 360 ASP 360 360 360 ASP ASP E . n 
E 1 361 TYR 361 361 361 TYR TYR E . n 
E 1 362 ALA 362 362 362 ALA ALA E . n 
E 1 363 ARG 363 363 363 ARG ARG E . n 
E 1 364 ASN 364 364 364 ASN ASN E . n 
E 1 365 ASN 365 365 365 ASN ASN E . n 
E 1 366 PHE 366 366 366 PHE PHE E . n 
E 1 367 PHE 367 367 367 PHE PHE E . n 
E 1 368 SER 368 368 368 SER SER E . n 
E 1 369 SER 369 369 369 SER SER E . n 
E 1 370 ILE 370 370 370 ILE ILE E . n 
E 1 371 LEU 371 371 371 LEU LEU E . n 
E 1 372 ASN 372 372 372 ASN ASN E . n 
E 1 373 VAL 373 373 373 VAL VAL E . n 
E 1 374 VAL 374 374 374 VAL VAL E . n 
E 1 375 PRO 375 375 375 PRO PRO E . n 
E 1 376 ALA 376 376 376 ALA ALA E . n 
E 1 377 GLY 377 377 377 GLY GLY E . n 
E 1 378 LEU 378 378 378 LEU LEU E . n 
E 1 379 ALA 379 379 379 ALA ALA E . n 
E 1 380 ASP 380 380 380 ASP ASP E . n 
E 1 381 LEU 381 381 381 LEU LEU E . n 
E 1 382 LEU 382 382 382 LEU LEU E . n 
E 1 383 ARG 383 383 383 ARG ARG E . n 
E 1 384 SER 384 384 384 SER SER E . n 
E 1 385 LEU 385 385 385 LEU LEU E . n 
E 1 386 GLU 386 386 386 GLU GLU E . n 
E 1 387 ARG 387 387 387 ARG ARG E . n 
E 1 388 ALA 388 388 388 ALA ALA E . n 
E 1 389 GLY 389 389 389 GLY GLY E . n 
E 1 390 VAL 390 390 390 VAL VAL E . n 
E 1 391 ARG 391 391 391 ARG ARG E . n 
E 1 392 TYR 392 392 392 TYR TYR E . n 
E 1 393 ASP 393 393 393 ASP ASP E . n 
E 1 394 LYS 394 394 394 LYS LYS E . n 
E 1 395 ASP 395 395 395 ASP ASP E . n 
E 1 396 SER 396 396 396 SER SER E . n 
E 1 397 GLY 397 397 397 GLY GLY E . n 
E 1 398 GLU 398 398 398 GLU GLU E . n 
E 1 399 GLY 399 399 399 GLY GLY E . n 
E 1 400 ALA 400 400 400 ALA ALA E . n 
E 1 401 VAL 401 401 401 VAL VAL E . n 
E 1 402 VAL 402 402 402 VAL VAL E . n 
E 1 403 LEU 403 403 403 LEU LEU E . n 
E 1 404 GLY 404 404 404 GLY GLY E . n 
E 1 405 CYS 405 405 405 CYS CYS E . n 
E 1 406 ASN 406 406 406 ASN ASN E . n 
E 1 407 SER 407 407 407 SER SER E . n 
E 1 408 ASP 408 408 408 ASP ASP E . n 
E 1 409 LEU 409 409 409 LEU LEU E . n 
E 1 410 GLY 410 410 410 GLY GLY E . n 
E 1 411 PRO 411 411 411 PRO PRO E . n 
E 1 412 GLY 412 412 412 GLY GLY E . n 
E 1 413 ALA 413 413 413 ALA ALA E . n 
E 1 414 GLU 414 414 414 GLU GLU E . n 
E 1 415 LEU 415 415 415 LEU LEU E . n 
E 1 416 LEU 416 416 416 LEU LEU E . n 
E 1 417 VAL 417 417 417 VAL VAL E . n 
E 1 418 PHE 418 418 418 PHE PHE E . n 
E 1 419 SER 419 419 419 SER SER E . n 
E 1 420 LYS 420 420 420 LYS LYS E . n 
E 1 421 ASP 421 421 421 ASP ASP E . n 
E 1 422 TRP 422 422 422 TRP TRP E . n 
E 1 423 ASP 423 423 423 ASP ASP E . n 
E 1 424 ARG 424 424 424 ARG ARG E . n 
E 1 425 LEU 425 425 425 LEU LEU E . n 
E 1 426 THR 426 426 426 THR THR E . n 
E 1 427 ALA 427 427 427 ALA ALA E . n 
E 1 428 MET 428 428 428 MET MET E . n 
E 1 429 LYS 429 429 429 LYS LYS E . n 
E 1 430 ASP 430 430 430 ASP ASP E . n 
E 1 431 GLU 431 431 431 GLU GLU E . n 
E 1 432 ILE 432 432 432 ILE ILE E . n 
E 1 433 ALA 433 433 433 ALA ALA E . n 
E 1 434 THR 434 434 434 THR THR E . n 
E 1 435 THR 435 435 435 THR THR E . n 
E 1 436 ALA 436 436 436 ALA ALA E . n 
E 1 437 GLY 437 437 437 GLY GLY E . n 
E 1 438 THR 438 438 438 THR THR E . n 
E 1 439 LEU 439 439 439 LEU LEU E . n 
E 1 440 SER 440 440 440 SER SER E . n 
E 1 441 LEU 441 441 ?   ?   ?   E . n 
E 1 442 GLU 442 442 ?   ?   ?   E . n 
E 1 443 HIS 443 443 ?   ?   ?   E . n 
E 1 444 HIS 444 444 ?   ?   ?   E . n 
E 1 445 HIS 445 445 ?   ?   ?   E . n 
E 1 446 HIS 446 446 ?   ?   ?   E . n 
E 1 447 HIS 447 447 ?   ?   ?   E . n 
E 1 448 HIS 448 448 ?   ?   ?   E . n 
F 1 1   MET 1   1   1   MET MET F . n 
F 1 2   PRO 2   2   2   PRO PRO F . n 
F 1 3   LYS 3   3   3   LYS LYS F . n 
F 1 4   ILE 4   4   4   ILE ILE F . n 
F 1 5   ILE 5   5   5   ILE ILE F . n 
F 1 6   LEU 6   6   6   LEU LEU F . n 
F 1 7   PRO 7   7   7   PRO PRO F . n 
F 1 8   ASN 8   8   8   ASN ASN F . n 
F 1 9   PHE 9   9   9   PHE PHE F . n 
F 1 10  ARG 10  10  ?   ?   ?   F . n 
F 1 11  ALA 11  11  ?   ?   ?   F . n 
F 1 12  ASP 12  12  ?   ?   ?   F . n 
F 1 13  TYR 13  13  ?   ?   ?   F . n 
F 1 14  SER 14  14  ?   ?   ?   F . n 
F 1 15  GLU 15  15  ?   ?   ?   F . n 
F 1 16  GLN 16  16  ?   ?   ?   F . n 
F 1 17  VAL 17  17  ?   ?   ?   F . n 
F 1 18  ARG 18  18  ?   ?   ?   F . n 
F 1 19  ASP 19  19  ?   ?   ?   F . n 
F 1 20  TRP 20  20  ?   ?   ?   F . n 
F 1 21  LEU 21  21  ?   ?   ?   F . n 
F 1 22  GLY 22  22  ?   ?   ?   F . n 
F 1 23  ILE 23  23  ?   ?   ?   F . n 
F 1 24  SER 24  24  ?   ?   ?   F . n 
F 1 25  ASP 25  25  ?   ?   ?   F . n 
F 1 26  ALA 26  26  ?   ?   ?   F . n 
F 1 27  THR 27  27  ?   ?   ?   F . n 
F 1 28  ALA 28  28  ?   ?   ?   F . n 
F 1 29  SER 29  29  ?   ?   ?   F . n 
F 1 30  SER 30  30  ?   ?   ?   F . n 
F 1 31  THR 31  31  31  THR THR F . n 
F 1 32  ASP 32  32  32  ASP ASP F . n 
F 1 33  THR 33  33  33  THR THR F . n 
F 1 34  THR 34  34  34  THR THR F . n 
F 1 35  ALA 35  35  35  ALA ALA F . n 
F 1 36  ARG 36  36  36  ARG ARG F . n 
F 1 37  PHE 37  37  37  PHE PHE F . n 
F 1 38  LEU 38  38  38  LEU LEU F . n 
F 1 39  TRP 39  39  39  TRP TRP F . n 
F 1 40  HIS 40  40  40  HIS HIS F . n 
F 1 41  ALA 41  41  41  ALA ALA F . n 
F 1 42  GLU 42  42  42  GLU GLU F . n 
F 1 43  ASP 43  43  43  ASP ASP F . n 
F 1 44  GLY 44  44  44  GLY GLY F . n 
F 1 45  ASP 45  45  45  ASP ASP F . n 
F 1 46  VAL 46  46  46  VAL VAL F . n 
F 1 47  LEU 47  47  47  LEU LEU F . n 
F 1 48  VAL 48  48  48  VAL VAL F . n 
F 1 49  ILE 49  49  49  ILE ILE F . n 
F 1 50  PRO 50  50  50  PRO PRO F . n 
F 1 51  ASP 51  51  51  ASP ASP F . n 
F 1 52  THR 52  52  52  THR THR F . n 
F 1 53  VAL 53  53  53  VAL VAL F . n 
F 1 54  ASP 54  54  54  ASP ASP F . n 
F 1 55  PRO 55  55  55  PRO PRO F . n 
F 1 56  ASP 56  56  56  ASP ASP F . n 
F 1 57  PHE 57  57  57  PHE PHE F . n 
F 1 58  PRO 58  58  58  PRO PRO F . n 
F 1 59  GLY 59  59  59  GLY GLY F . n 
F 1 60  TYR 60  60  60  TYR TYR F . n 
F 1 61  VAL 61  61  61  VAL VAL F . n 
F 1 62  ALA 62  62  62  ALA ALA F . n 
F 1 63  ASP 63  63  63  ASP ASP F . n 
F 1 64  THR 64  64  64  THR THR F . n 
F 1 65  LEU 65  65  65  LEU LEU F . n 
F 1 66  GLY 66  66  66  GLY GLY F . n 
F 1 67  ILE 67  67  67  ILE ILE F . n 
F 1 68  ASP 68  68  68  ASP ASP F . n 
F 1 69  GLY 69  69  69  GLY GLY F . n 
F 1 70  THR 70  70  70  THR THR F . n 
F 1 71  SER 71  71  71  SER SER F . n 
F 1 72  VAL 72  72  72  VAL VAL F . n 
F 1 73  HIS 73  73  73  HIS HIS F . n 
F 1 74  VAL 74  74  74  VAL VAL F . n 
F 1 75  GLU 75  75  75  GLU GLU F . n 
F 1 76  ARG 76  76  76  ARG ARG F . n 
F 1 77  THR 77  77  77  THR THR F . n 
F 1 78  GLN 78  78  78  GLN GLN F . n 
F 1 79  THR 79  79  79  THR THR F . n 
F 1 80  PRO 80  80  80  PRO PRO F . n 
F 1 81  LEU 81  81  81  LEU LEU F . n 
F 1 82  SER 82  82  82  SER SER F . n 
F 1 83  GLU 83  83  83  GLU GLU F . n 
F 1 84  ALA 84  84  84  ALA ALA F . n 
F 1 85  VAL 85  85  85  VAL VAL F . n 
F 1 86  LEU 86  86  86  LEU LEU F . n 
F 1 87  GLN 87  87  87  GLN GLN F . n 
F 1 88  ASP 88  88  88  ASP ASP F . n 
F 1 89  PRO 89  89  89  PRO PRO F . n 
F 1 90  GLU 90  90  90  GLU GLU F . n 
F 1 91  PHE 91  91  91  PHE PHE F . n 
F 1 92  ILE 92  92  92  ILE ILE F . n 
F 1 93  ASP 93  93  93  ASP ASP F . n 
F 1 94  ARG 94  94  94  ARG ARG F . n 
F 1 95  LEU 95  95  95  LEU LEU F . n 
F 1 96  ALA 96  96  96  ALA ALA F . n 
F 1 97  ALA 97  97  97  ALA ALA F . n 
F 1 98  HIS 98  98  98  HIS HIS F . n 
F 1 99  THR 99  99  99  THR THR F . n 
F 1 100 GLY 100 100 100 GLY GLY F . n 
F 1 101 THR 101 101 101 THR THR F . n 
F 1 102 GLY 102 102 102 GLY GLY F . n 
F 1 103 ALA 103 103 103 ALA ALA F . n 
F 1 104 GLY 104 104 104 GLY GLY F . n 
F 1 105 TRP 105 105 105 TRP TRP F . n 
F 1 106 SER 106 106 106 SER SER F . n 
F 1 107 LEU 107 107 107 LEU LEU F . n 
F 1 108 PHE 108 108 108 PHE PHE F . n 
F 1 109 PRO 109 109 109 PRO PRO F . n 
F 1 110 CYS 110 110 110 CYS CYS F . n 
F 1 111 VAL 111 111 111 VAL VAL F . n 
F 1 112 SER 112 112 112 SER SER F . n 
F 1 113 THR 113 113 113 THR THR F . n 
F 1 114 ARG 114 114 114 ARG ARG F . n 
F 1 115 ALA 115 115 115 ALA ALA F . n 
F 1 116 ALA 116 116 116 ALA ALA F . n 
F 1 117 ALA 117 117 117 ALA ALA F . n 
F 1 118 GLN 118 118 118 GLN GLN F . n 
F 1 119 LEU 119 119 119 LEU LEU F . n 
F 1 120 THR 120 120 120 THR THR F . n 
F 1 121 ARG 121 121 121 ARG ARG F . n 
F 1 122 LYS 122 122 122 LYS LYS F . n 
F 1 123 LEU 123 123 123 LEU LEU F . n 
F 1 124 ASN 124 124 124 ASN ASN F . n 
F 1 125 VAL 125 125 125 VAL VAL F . n 
F 1 126 ALA 126 126 126 ALA ALA F . n 
F 1 127 ALA 127 127 127 ALA ALA F . n 
F 1 128 LEU 128 128 128 LEU LEU F . n 
F 1 129 ASP 129 129 129 ASP ASP F . n 
F 1 130 GLY 130 130 130 GLY GLY F . n 
F 1 131 TYR 131 131 131 TYR TYR F . n 
F 1 132 GLU 132 132 132 GLU GLU F . n 
F 1 133 PHE 133 133 133 PHE PHE F . n 
F 1 134 ALA 134 134 134 ALA ALA F . n 
F 1 135 MET 135 135 135 MET MET F . n 
F 1 136 GLN 136 136 136 GLN GLN F . n 
F 1 137 ASN 137 137 137 ASN ASN F . n 
F 1 138 GLY 138 138 138 GLY GLY F . n 
F 1 139 ILE 139 139 139 ILE ILE F . n 
F 1 140 ASP 140 140 140 ASP ASP F . n 
F 1 141 LEU 141 141 141 LEU LEU F . n 
F 1 142 LEU 142 142 142 LEU LEU F . n 
F 1 143 ASN 143 143 143 ASN ASN F . n 
F 1 144 MET 144 144 144 MET MET F . n 
F 1 145 LYS 145 145 145 LYS LYS F . n 
F 1 146 SER 146 146 146 SER SER F . n 
F 1 147 THR 147 147 147 THR THR F . n 
F 1 148 PHE 148 148 148 PHE PHE F . n 
F 1 149 ARG 149 149 149 ARG ARG F . n 
F 1 150 ARG 150 150 150 ARG ARG F . n 
F 1 151 LEU 151 151 151 LEU LEU F . n 
F 1 152 ALA 152 152 152 ALA ALA F . n 
F 1 153 ALA 153 153 153 ALA ALA F . n 
F 1 154 GLY 154 154 154 GLY GLY F . n 
F 1 155 LEU 155 155 155 LEU LEU F . n 
F 1 156 GLY 156 156 156 GLY GLY F . n 
F 1 157 THR 157 157 157 THR THR F . n 
F 1 158 PRO 158 158 158 PRO PRO F . n 
F 1 159 LEU 159 159 159 LEU LEU F . n 
F 1 160 THR 160 160 160 THR THR F . n 
F 1 161 ASP 161 161 161 ASP ASP F . n 
F 1 162 GLY 162 162 162 GLY GLY F . n 
F 1 163 VAL 163 163 163 VAL VAL F . n 
F 1 164 VAL 164 164 164 VAL VAL F . n 
F 1 165 ALA 165 165 165 ALA ALA F . n 
F 1 166 ARG 166 166 166 ARG ARG F . n 
F 1 167 GLY 167 167 167 GLY GLY F . n 
F 1 168 PRO 168 168 168 PRO PRO F . n 
F 1 169 ALA 169 169 169 ALA ALA F . n 
F 1 170 GLU 170 170 170 GLU GLU F . n 
F 1 171 VAL 171 171 171 VAL VAL F . n 
F 1 172 ARG 172 172 172 ARG ARG F . n 
F 1 173 SER 173 173 173 SER SER F . n 
F 1 174 ALA 174 174 174 ALA ALA F . n 
F 1 175 ILE 175 175 175 ILE ILE F . n 
F 1 176 GLN 176 176 176 GLN GLN F . n 
F 1 177 GLU 177 177 177 GLU GLU F . n 
F 1 178 LEU 178 178 178 LEU LEU F . n 
F 1 179 ILE 179 179 179 ILE ILE F . n 
F 1 180 ALA 180 180 180 ALA ALA F . n 
F 1 181 GLU 181 181 181 GLU GLU F . n 
F 1 182 THR 182 182 182 THR THR F . n 
F 1 183 GLY 183 183 183 GLY GLY F . n 
F 1 184 MET 184 184 184 MET MET F . n 
F 1 185 VAL 185 185 185 VAL VAL F . n 
F 1 186 ILE 186 186 186 ILE ILE F . n 
F 1 187 ALA 187 187 187 ALA ALA F . n 
F 1 188 LYS 188 188 188 LYS LYS F . n 
F 1 189 GLN 189 189 189 GLN GLN F . n 
F 1 190 ASP 190 190 190 ASP ASP F . n 
F 1 191 ARG 191 191 191 ARG ARG F . n 
F 1 192 SER 192 192 192 SER SER F . n 
F 1 193 GLY 193 193 193 GLY GLY F . n 
F 1 194 GLY 194 194 194 GLY GLY F . n 
F 1 195 GLY 195 195 195 GLY GLY F . n 
F 1 196 HIS 196 196 196 HIS HIS F . n 
F 1 197 GLY 197 197 197 GLY GLY F . n 
F 1 198 ASN 198 198 198 ASN ASN F . n 
F 1 199 ILE 199 199 199 ILE ILE F . n 
F 1 200 GLY 200 200 200 GLY GLY F . n 
F 1 201 ILE 201 201 201 ILE ILE F . n 
F 1 202 SER 202 202 202 SER SER F . n 
F 1 203 THR 203 203 203 THR THR F . n 
F 1 204 SER 204 204 204 SER SER F . n 
F 1 205 PRO 205 205 205 PRO PRO F . n 
F 1 206 GLU 206 206 206 GLU GLU F . n 
F 1 207 SER 207 207 207 SER SER F . n 
F 1 208 SER 208 208 208 SER SER F . n 
F 1 209 PHE 209 209 209 PHE PHE F . n 
F 1 210 PRO 210 210 210 PRO PRO F . n 
F 1 211 GLY 211 211 211 GLY GLY F . n 
F 1 212 THR 212 212 212 THR THR F . n 
F 1 213 ARG 213 213 213 ARG ARG F . n 
F 1 214 GLU 214 214 214 GLU GLU F . n 
F 1 215 VAL 215 215 215 VAL VAL F . n 
F 1 216 LEU 216 216 216 LEU LEU F . n 
F 1 217 ALA 217 217 217 ALA ALA F . n 
F 1 218 TYR 218 218 218 TYR TYR F . n 
F 1 219 ALA 219 219 219 ALA ALA F . n 
F 1 220 ASN 220 220 220 ASN ASN F . n 
F 1 221 ASP 221 221 221 ASP ASP F . n 
F 1 222 GLN 222 222 222 GLN GLN F . n 
F 1 223 LEU 223 223 223 LEU LEU F . n 
F 1 224 ASP 224 224 224 ASP ASP F . n 
F 1 225 THR 225 225 225 THR THR F . n 
F 1 226 LEU 226 226 226 LEU LEU F . n 
F 1 227 ALA 227 227 227 ALA ALA F . n 
F 1 228 ASP 228 228 228 ASP ASP F . n 
F 1 229 THR 229 229 229 THR THR F . n 
F 1 230 LEU 230 230 230 LEU LEU F . n 
F 1 231 TRP 231 231 231 TRP TRP F . n 
F 1 232 SER 232 232 232 SER SER F . n 
F 1 233 GLN 233 233 233 GLN GLN F . n 
F 1 234 LEU 234 234 234 LEU LEU F . n 
F 1 235 THR 235 235 235 THR THR F . n 
F 1 236 ASP 236 236 236 ASP ASP F . n 
F 1 237 THR 237 237 237 THR THR F . n 
F 1 238 GLN 238 238 238 GLN GLN F . n 
F 1 239 ASN 239 239 239 ASN ASN F . n 
F 1 240 GLN 240 240 240 GLN GLN F . n 
F 1 241 PHE 241 241 241 PHE PHE F . n 
F 1 242 ILE 242 242 242 ILE ILE F . n 
F 1 243 THR 243 243 243 THR THR F . n 
F 1 244 VAL 244 244 244 VAL VAL F . n 
F 1 245 GLU 245 245 245 GLU GLU F . n 
F 1 246 THR 246 246 246 THR THR F . n 
F 1 247 TYR 247 247 247 TYR TYR F . n 
F 1 248 HIS 248 248 248 HIS HIS F . n 
F 1 249 ARG 249 249 249 ARG ARG F . n 
F 1 250 ALA 250 250 250 ALA ALA F . n 
F 1 251 ASP 251 251 251 ASP ASP F . n 
F 1 252 GLN 252 252 252 GLN GLN F . n 
F 1 253 ARG 253 253 253 ARG ARG F . n 
F 1 254 PHE 254 254 254 PHE PHE F . n 
F 1 255 PHE 255 255 255 PHE PHE F . n 
F 1 256 PHE 256 256 256 PHE PHE F . n 
F 1 257 GLU 257 257 257 GLU GLU F . n 
F 1 258 TYR 258 258 258 TYR TYR F . n 
F 1 259 HIS 259 259 259 HIS HIS F . n 
F 1 260 LEU 260 260 260 LEU LEU F . n 
F 1 261 ASP 261 261 261 ASP ASP F . n 
F 1 262 GLY 262 262 262 GLY GLY F . n 
F 1 263 ASP 263 263 263 ASP ASP F . n 
F 1 264 ARG 264 264 264 ARG ARG F . n 
F 1 265 ALA 265 265 265 ALA ALA F . n 
F 1 266 ARG 266 266 266 ARG ARG F . n 
F 1 267 PHE 267 267 267 PHE PHE F . n 
F 1 268 LEU 268 268 268 LEU LEU F . n 
F 1 269 HIS 269 269 269 HIS HIS F . n 
F 1 270 SER 270 270 270 SER SER F . n 
F 1 271 SER 271 271 271 SER SER F . n 
F 1 272 ILE 272 272 272 ILE ILE F . n 
F 1 273 LEU 273 273 273 LEU LEU F . n 
F 1 274 LYS 274 274 274 LYS LYS F . n 
F 1 275 TYR 275 275 275 TYR TYR F . n 
F 1 276 GLU 276 276 276 GLU GLU F . n 
F 1 277 GLN 277 277 277 GLN GLN F . n 
F 1 278 LEU 278 278 ?   ?   ?   F . n 
F 1 279 PRO 279 279 ?   ?   ?   F . n 
F 1 280 GLU 280 280 ?   ?   ?   F . n 
F 1 281 GLY 281 281 ?   ?   ?   F . n 
F 1 282 SER 282 282 ?   ?   ?   F . n 
F 1 283 GLY 283 283 ?   ?   ?   F . n 
F 1 284 GLY 284 284 284 GLY GLY F . n 
F 1 285 SER 285 285 285 SER SER F . n 
F 1 286 ALA 286 286 286 ALA ALA F . n 
F 1 287 LYS 287 287 287 LYS LYS F . n 
F 1 288 TRP 288 288 288 TRP TRP F . n 
F 1 289 ILE 289 289 289 ILE ILE F . n 
F 1 290 GLY 290 290 290 GLY GLY F . n 
F 1 291 LEU 291 291 291 LEU LEU F . n 
F 1 292 ASP 292 292 292 ASP ASP F . n 
F 1 293 SER 293 293 293 SER SER F . n 
F 1 294 PRO 294 294 294 PRO PRO F . n 
F 1 295 SER 295 295 295 SER SER F . n 
F 1 296 ARG 296 296 296 ARG ARG F . n 
F 1 297 SER 297 297 297 SER SER F . n 
F 1 298 GLU 298 298 298 GLU GLU F . n 
F 1 299 PHE 299 299 299 PHE PHE F . n 
F 1 300 GLU 300 300 300 GLU GLU F . n 
F 1 301 ALA 301 301 301 ALA ALA F . n 
F 1 302 THR 302 302 302 THR THR F . n 
F 1 303 LEU 303 303 303 LEU LEU F . n 
F 1 304 LYS 304 304 304 LYS LYS F . n 
F 1 305 PRO 305 305 305 PRO PRO F . n 
F 1 306 ALA 306 306 306 ALA ALA F . n 
F 1 307 GLU 307 307 307 GLU GLU F . n 
F 1 308 GLU 308 308 308 GLU GLU F . n 
F 1 309 PHE 309 309 309 PHE PHE F . n 
F 1 310 ILE 310 310 310 ILE ILE F . n 
F 1 311 GLU 311 311 311 GLU GLU F . n 
F 1 312 MET 312 312 312 MET MET F . n 
F 1 313 ILE 313 313 313 ILE ILE F . n 
F 1 314 ARG 314 314 314 ARG ARG F . n 
F 1 315 THR 315 315 315 THR THR F . n 
F 1 316 ILE 316 316 316 ILE ILE F . n 
F 1 317 GLY 317 317 317 GLY GLY F . n 
F 1 318 TYR 318 318 318 TYR TYR F . n 
F 1 319 ARG 319 319 319 ARG ARG F . n 
F 1 320 GLY 320 320 320 GLY GLY F . n 
F 1 321 TYR 321 321 321 TYR TYR F . n 
F 1 322 VAL 322 322 322 VAL VAL F . n 
F 1 323 ASN 323 323 323 ASN ASN F . n 
F 1 324 ILE 324 324 324 ILE ILE F . n 
F 1 325 ASP 325 325 325 ASP ASP F . n 
F 1 326 GLY 326 326 326 GLY GLY F . n 
F 1 327 ILE 327 327 327 ILE ILE F . n 
F 1 328 VAL 328 328 328 VAL VAL F . n 
F 1 329 LEU 329 329 329 LEU LEU F . n 
F 1 330 ASP 330 330 330 ASP ASP F . n 
F 1 331 ASP 331 331 331 ASP ASP F . n 
F 1 332 GLY 332 332 332 GLY GLY F . n 
F 1 333 ARG 333 333 333 ARG ARG F . n 
F 1 334 VAL 334 334 334 VAL VAL F . n 
F 1 335 PHE 335 335 335 PHE PHE F . n 
F 1 336 PHE 336 336 336 PHE PHE F . n 
F 1 337 HIS 337 337 337 HIS HIS F . n 
F 1 338 GLU 338 338 338 GLU GLU F . n 
F 1 339 ILE 339 339 339 ILE ILE F . n 
F 1 340 ASN 340 340 340 ASN ASN F . n 
F 1 341 ALA 341 341 341 ALA ALA F . n 
F 1 342 ARG 342 342 342 ARG ARG F . n 
F 1 343 TRP 343 343 343 TRP TRP F . n 
F 1 344 SER 344 344 344 SER SER F . n 
F 1 345 GLY 345 345 345 GLY GLY F . n 
F 1 346 GLY 346 346 346 GLY GLY F . n 
F 1 347 LEU 347 347 347 LEU LEU F . n 
F 1 348 ILE 348 348 348 ILE ILE F . n 
F 1 349 TYR 349 349 349 TYR TYR F . n 
F 1 350 HIS 350 350 350 HIS HIS F . n 
F 1 351 THR 351 351 351 THR THR F . n 
F 1 352 VAL 352 352 352 VAL VAL F . n 
F 1 353 ALA 353 353 353 ALA ALA F . n 
F 1 354 GLU 354 354 354 GLU GLU F . n 
F 1 355 ARG 355 355 355 ARG ARG F . n 
F 1 356 LEU 356 356 356 LEU LEU F . n 
F 1 357 LEU 357 357 357 LEU LEU F . n 
F 1 358 GLY 358 358 358 GLY GLY F . n 
F 1 359 HIS 359 359 359 HIS HIS F . n 
F 1 360 ASP 360 360 360 ASP ASP F . n 
F 1 361 TYR 361 361 361 TYR TYR F . n 
F 1 362 ALA 362 362 362 ALA ALA F . n 
F 1 363 ARG 363 363 363 ARG ARG F . n 
F 1 364 ASN 364 364 364 ASN ASN F . n 
F 1 365 ASN 365 365 365 ASN ASN F . n 
F 1 366 PHE 366 366 366 PHE PHE F . n 
F 1 367 PHE 367 367 367 PHE PHE F . n 
F 1 368 SER 368 368 368 SER SER F . n 
F 1 369 SER 369 369 369 SER SER F . n 
F 1 370 ILE 370 370 370 ILE ILE F . n 
F 1 371 LEU 371 371 371 LEU LEU F . n 
F 1 372 ASN 372 372 372 ASN ASN F . n 
F 1 373 VAL 373 373 373 VAL VAL F . n 
F 1 374 VAL 374 374 374 VAL VAL F . n 
F 1 375 PRO 375 375 375 PRO PRO F . n 
F 1 376 ALA 376 376 376 ALA ALA F . n 
F 1 377 GLY 377 377 377 GLY GLY F . n 
F 1 378 LEU 378 378 378 LEU LEU F . n 
F 1 379 ALA 379 379 379 ALA ALA F . n 
F 1 380 ASP 380 380 380 ASP ASP F . n 
F 1 381 LEU 381 381 381 LEU LEU F . n 
F 1 382 LEU 382 382 382 LEU LEU F . n 
F 1 383 ARG 383 383 383 ARG ARG F . n 
F 1 384 SER 384 384 384 SER SER F . n 
F 1 385 LEU 385 385 385 LEU LEU F . n 
F 1 386 GLU 386 386 386 GLU GLU F . n 
F 1 387 ARG 387 387 387 ARG ARG F . n 
F 1 388 ALA 388 388 388 ALA ALA F . n 
F 1 389 GLY 389 389 389 GLY GLY F . n 
F 1 390 VAL 390 390 390 VAL VAL F . n 
F 1 391 ARG 391 391 391 ARG ARG F . n 
F 1 392 TYR 392 392 392 TYR TYR F . n 
F 1 393 ASP 393 393 393 ASP ASP F . n 
F 1 394 LYS 394 394 394 LYS LYS F . n 
F 1 395 ASP 395 395 395 ASP ASP F . n 
F 1 396 SER 396 396 396 SER SER F . n 
F 1 397 GLY 397 397 397 GLY GLY F . n 
F 1 398 GLU 398 398 398 GLU GLU F . n 
F 1 399 GLY 399 399 399 GLY GLY F . n 
F 1 400 ALA 400 400 400 ALA ALA F . n 
F 1 401 VAL 401 401 401 VAL VAL F . n 
F 1 402 VAL 402 402 402 VAL VAL F . n 
F 1 403 LEU 403 403 403 LEU LEU F . n 
F 1 404 GLY 404 404 404 GLY GLY F . n 
F 1 405 CYS 405 405 405 CYS CYS F . n 
F 1 406 ASN 406 406 406 ASN ASN F . n 
F 1 407 SER 407 407 407 SER SER F . n 
F 1 408 ASP 408 408 408 ASP ASP F . n 
F 1 409 LEU 409 409 409 LEU LEU F . n 
F 1 410 GLY 410 410 410 GLY GLY F . n 
F 1 411 PRO 411 411 411 PRO PRO F . n 
F 1 412 GLY 412 412 412 GLY GLY F . n 
F 1 413 ALA 413 413 413 ALA ALA F . n 
F 1 414 GLU 414 414 414 GLU GLU F . n 
F 1 415 LEU 415 415 415 LEU LEU F . n 
F 1 416 LEU 416 416 416 LEU LEU F . n 
F 1 417 VAL 417 417 417 VAL VAL F . n 
F 1 418 PHE 418 418 418 PHE PHE F . n 
F 1 419 SER 419 419 419 SER SER F . n 
F 1 420 LYS 420 420 420 LYS LYS F . n 
F 1 421 ASP 421 421 421 ASP ASP F . n 
F 1 422 TRP 422 422 422 TRP TRP F . n 
F 1 423 ASP 423 423 423 ASP ASP F . n 
F 1 424 ARG 424 424 424 ARG ARG F . n 
F 1 425 LEU 425 425 425 LEU LEU F . n 
F 1 426 THR 426 426 426 THR THR F . n 
F 1 427 ALA 427 427 427 ALA ALA F . n 
F 1 428 MET 428 428 428 MET MET F . n 
F 1 429 LYS 429 429 429 LYS LYS F . n 
F 1 430 ASP 430 430 430 ASP ASP F . n 
F 1 431 GLU 431 431 431 GLU GLU F . n 
F 1 432 ILE 432 432 432 ILE ILE F . n 
F 1 433 ALA 433 433 433 ALA ALA F . n 
F 1 434 THR 434 434 434 THR THR F . n 
F 1 435 THR 435 435 435 THR THR F . n 
F 1 436 ALA 436 436 436 ALA ALA F . n 
F 1 437 GLY 437 437 437 GLY GLY F . n 
F 1 438 THR 438 438 438 THR THR F . n 
F 1 439 LEU 439 439 439 LEU LEU F . n 
F 1 440 SER 440 440 440 SER SER F . n 
F 1 441 LEU 441 441 ?   ?   ?   F . n 
F 1 442 GLU 442 442 ?   ?   ?   F . n 
F 1 443 HIS 443 443 ?   ?   ?   F . n 
F 1 444 HIS 444 444 ?   ?   ?   F . n 
F 1 445 HIS 445 445 ?   ?   ?   F . n 
F 1 446 HIS 446 446 ?   ?   ?   F . n 
F 1 447 HIS 447 447 ?   ?   ?   F . n 
F 1 448 HIS 448 448 ?   ?   ?   F . n 
G 1 1   MET 1   1   ?   ?   ?   G . n 
G 1 2   PRO 2   2   2   PRO PRO G . n 
G 1 3   LYS 3   3   3   LYS LYS G . n 
G 1 4   ILE 4   4   4   ILE ILE G . n 
G 1 5   ILE 5   5   5   ILE ILE G . n 
G 1 6   LEU 6   6   6   LEU LEU G . n 
G 1 7   PRO 7   7   7   PRO PRO G . n 
G 1 8   ASN 8   8   8   ASN ASN G . n 
G 1 9   PHE 9   9   9   PHE PHE G . n 
G 1 10  ARG 10  10  10  ARG ARG G . n 
G 1 11  ALA 11  11  11  ALA ALA G . n 
G 1 12  ASP 12  12  ?   ?   ?   G . n 
G 1 13  TYR 13  13  ?   ?   ?   G . n 
G 1 14  SER 14  14  ?   ?   ?   G . n 
G 1 15  GLU 15  15  ?   ?   ?   G . n 
G 1 16  GLN 16  16  ?   ?   ?   G . n 
G 1 17  VAL 17  17  ?   ?   ?   G . n 
G 1 18  ARG 18  18  ?   ?   ?   G . n 
G 1 19  ASP 19  19  ?   ?   ?   G . n 
G 1 20  TRP 20  20  ?   ?   ?   G . n 
G 1 21  LEU 21  21  ?   ?   ?   G . n 
G 1 22  GLY 22  22  ?   ?   ?   G . n 
G 1 23  ILE 23  23  ?   ?   ?   G . n 
G 1 24  SER 24  24  ?   ?   ?   G . n 
G 1 25  ASP 25  25  ?   ?   ?   G . n 
G 1 26  ALA 26  26  ?   ?   ?   G . n 
G 1 27  THR 27  27  ?   ?   ?   G . n 
G 1 28  ALA 28  28  ?   ?   ?   G . n 
G 1 29  SER 29  29  29  SER SER G . n 
G 1 30  SER 30  30  30  SER SER G . n 
G 1 31  THR 31  31  31  THR THR G . n 
G 1 32  ASP 32  32  32  ASP ASP G . n 
G 1 33  THR 33  33  33  THR THR G . n 
G 1 34  THR 34  34  34  THR THR G . n 
G 1 35  ALA 35  35  35  ALA ALA G . n 
G 1 36  ARG 36  36  36  ARG ARG G . n 
G 1 37  PHE 37  37  37  PHE PHE G . n 
G 1 38  LEU 38  38  38  LEU LEU G . n 
G 1 39  TRP 39  39  39  TRP TRP G . n 
G 1 40  HIS 40  40  40  HIS HIS G . n 
G 1 41  ALA 41  41  41  ALA ALA G . n 
G 1 42  GLU 42  42  42  GLU GLU G . n 
G 1 43  ASP 43  43  43  ASP ASP G . n 
G 1 44  GLY 44  44  44  GLY GLY G . n 
G 1 45  ASP 45  45  45  ASP ASP G . n 
G 1 46  VAL 46  46  46  VAL VAL G . n 
G 1 47  LEU 47  47  47  LEU LEU G . n 
G 1 48  VAL 48  48  48  VAL VAL G . n 
G 1 49  ILE 49  49  49  ILE ILE G . n 
G 1 50  PRO 50  50  50  PRO PRO G . n 
G 1 51  ASP 51  51  51  ASP ASP G . n 
G 1 52  THR 52  52  52  THR THR G . n 
G 1 53  VAL 53  53  53  VAL VAL G . n 
G 1 54  ASP 54  54  54  ASP ASP G . n 
G 1 55  PRO 55  55  55  PRO PRO G . n 
G 1 56  ASP 56  56  56  ASP ASP G . n 
G 1 57  PHE 57  57  57  PHE PHE G . n 
G 1 58  PRO 58  58  58  PRO PRO G . n 
G 1 59  GLY 59  59  59  GLY GLY G . n 
G 1 60  TYR 60  60  60  TYR TYR G . n 
G 1 61  VAL 61  61  61  VAL VAL G . n 
G 1 62  ALA 62  62  62  ALA ALA G . n 
G 1 63  ASP 63  63  63  ASP ASP G . n 
G 1 64  THR 64  64  64  THR THR G . n 
G 1 65  LEU 65  65  65  LEU LEU G . n 
G 1 66  GLY 66  66  66  GLY GLY G . n 
G 1 67  ILE 67  67  67  ILE ILE G . n 
G 1 68  ASP 68  68  68  ASP ASP G . n 
G 1 69  GLY 69  69  69  GLY GLY G . n 
G 1 70  THR 70  70  70  THR THR G . n 
G 1 71  SER 71  71  71  SER SER G . n 
G 1 72  VAL 72  72  72  VAL VAL G . n 
G 1 73  HIS 73  73  73  HIS HIS G . n 
G 1 74  VAL 74  74  74  VAL VAL G . n 
G 1 75  GLU 75  75  75  GLU GLU G . n 
G 1 76  ARG 76  76  76  ARG ARG G . n 
G 1 77  THR 77  77  77  THR THR G . n 
G 1 78  GLN 78  78  78  GLN GLN G . n 
G 1 79  THR 79  79  79  THR THR G . n 
G 1 80  PRO 80  80  80  PRO PRO G . n 
G 1 81  LEU 81  81  81  LEU LEU G . n 
G 1 82  SER 82  82  82  SER SER G . n 
G 1 83  GLU 83  83  83  GLU GLU G . n 
G 1 84  ALA 84  84  84  ALA ALA G . n 
G 1 85  VAL 85  85  85  VAL VAL G . n 
G 1 86  LEU 86  86  86  LEU LEU G . n 
G 1 87  GLN 87  87  87  GLN GLN G . n 
G 1 88  ASP 88  88  88  ASP ASP G . n 
G 1 89  PRO 89  89  89  PRO PRO G . n 
G 1 90  GLU 90  90  90  GLU GLU G . n 
G 1 91  PHE 91  91  91  PHE PHE G . n 
G 1 92  ILE 92  92  92  ILE ILE G . n 
G 1 93  ASP 93  93  93  ASP ASP G . n 
G 1 94  ARG 94  94  94  ARG ARG G . n 
G 1 95  LEU 95  95  95  LEU LEU G . n 
G 1 96  ALA 96  96  96  ALA ALA G . n 
G 1 97  ALA 97  97  97  ALA ALA G . n 
G 1 98  HIS 98  98  98  HIS HIS G . n 
G 1 99  THR 99  99  99  THR THR G . n 
G 1 100 GLY 100 100 100 GLY GLY G . n 
G 1 101 THR 101 101 101 THR THR G . n 
G 1 102 GLY 102 102 102 GLY GLY G . n 
G 1 103 ALA 103 103 103 ALA ALA G . n 
G 1 104 GLY 104 104 104 GLY GLY G . n 
G 1 105 TRP 105 105 105 TRP TRP G . n 
G 1 106 SER 106 106 106 SER SER G . n 
G 1 107 LEU 107 107 107 LEU LEU G . n 
G 1 108 PHE 108 108 108 PHE PHE G . n 
G 1 109 PRO 109 109 109 PRO PRO G . n 
G 1 110 CYS 110 110 110 CYS CYS G . n 
G 1 111 VAL 111 111 111 VAL VAL G . n 
G 1 112 SER 112 112 112 SER SER G . n 
G 1 113 THR 113 113 113 THR THR G . n 
G 1 114 ARG 114 114 114 ARG ARG G . n 
G 1 115 ALA 115 115 115 ALA ALA G . n 
G 1 116 ALA 116 116 116 ALA ALA G . n 
G 1 117 ALA 117 117 117 ALA ALA G . n 
G 1 118 GLN 118 118 118 GLN GLN G . n 
G 1 119 LEU 119 119 119 LEU LEU G . n 
G 1 120 THR 120 120 120 THR THR G . n 
G 1 121 ARG 121 121 121 ARG ARG G . n 
G 1 122 LYS 122 122 122 LYS LYS G . n 
G 1 123 LEU 123 123 123 LEU LEU G . n 
G 1 124 ASN 124 124 124 ASN ASN G . n 
G 1 125 VAL 125 125 125 VAL VAL G . n 
G 1 126 ALA 126 126 126 ALA ALA G . n 
G 1 127 ALA 127 127 127 ALA ALA G . n 
G 1 128 LEU 128 128 128 LEU LEU G . n 
G 1 129 ASP 129 129 129 ASP ASP G . n 
G 1 130 GLY 130 130 130 GLY GLY G . n 
G 1 131 TYR 131 131 131 TYR TYR G . n 
G 1 132 GLU 132 132 132 GLU GLU G . n 
G 1 133 PHE 133 133 133 PHE PHE G . n 
G 1 134 ALA 134 134 134 ALA ALA G . n 
G 1 135 MET 135 135 135 MET MET G . n 
G 1 136 GLN 136 136 136 GLN GLN G . n 
G 1 137 ASN 137 137 137 ASN ASN G . n 
G 1 138 GLY 138 138 138 GLY GLY G . n 
G 1 139 ILE 139 139 139 ILE ILE G . n 
G 1 140 ASP 140 140 140 ASP ASP G . n 
G 1 141 LEU 141 141 141 LEU LEU G . n 
G 1 142 LEU 142 142 142 LEU LEU G . n 
G 1 143 ASN 143 143 143 ASN ASN G . n 
G 1 144 MET 144 144 144 MET MET G . n 
G 1 145 LYS 145 145 145 LYS LYS G . n 
G 1 146 SER 146 146 146 SER SER G . n 
G 1 147 THR 147 147 147 THR THR G . n 
G 1 148 PHE 148 148 148 PHE PHE G . n 
G 1 149 ARG 149 149 149 ARG ARG G . n 
G 1 150 ARG 150 150 150 ARG ARG G . n 
G 1 151 LEU 151 151 151 LEU LEU G . n 
G 1 152 ALA 152 152 152 ALA ALA G . n 
G 1 153 ALA 153 153 153 ALA ALA G . n 
G 1 154 GLY 154 154 154 GLY GLY G . n 
G 1 155 LEU 155 155 155 LEU LEU G . n 
G 1 156 GLY 156 156 156 GLY GLY G . n 
G 1 157 THR 157 157 157 THR THR G . n 
G 1 158 PRO 158 158 158 PRO PRO G . n 
G 1 159 LEU 159 159 159 LEU LEU G . n 
G 1 160 THR 160 160 160 THR THR G . n 
G 1 161 ASP 161 161 161 ASP ASP G . n 
G 1 162 GLY 162 162 162 GLY GLY G . n 
G 1 163 VAL 163 163 163 VAL VAL G . n 
G 1 164 VAL 164 164 164 VAL VAL G . n 
G 1 165 ALA 165 165 165 ALA ALA G . n 
G 1 166 ARG 166 166 166 ARG ARG G . n 
G 1 167 GLY 167 167 167 GLY GLY G . n 
G 1 168 PRO 168 168 168 PRO PRO G . n 
G 1 169 ALA 169 169 169 ALA ALA G . n 
G 1 170 GLU 170 170 170 GLU GLU G . n 
G 1 171 VAL 171 171 171 VAL VAL G . n 
G 1 172 ARG 172 172 172 ARG ARG G . n 
G 1 173 SER 173 173 173 SER SER G . n 
G 1 174 ALA 174 174 174 ALA ALA G . n 
G 1 175 ILE 175 175 175 ILE ILE G . n 
G 1 176 GLN 176 176 176 GLN GLN G . n 
G 1 177 GLU 177 177 177 GLU GLU G . n 
G 1 178 LEU 178 178 178 LEU LEU G . n 
G 1 179 ILE 179 179 179 ILE ILE G . n 
G 1 180 ALA 180 180 180 ALA ALA G . n 
G 1 181 GLU 181 181 181 GLU GLU G . n 
G 1 182 THR 182 182 182 THR THR G . n 
G 1 183 GLY 183 183 183 GLY GLY G . n 
G 1 184 MET 184 184 184 MET MET G . n 
G 1 185 VAL 185 185 185 VAL VAL G . n 
G 1 186 ILE 186 186 186 ILE ILE G . n 
G 1 187 ALA 187 187 187 ALA ALA G . n 
G 1 188 LYS 188 188 188 LYS LYS G . n 
G 1 189 GLN 189 189 189 GLN GLN G . n 
G 1 190 ASP 190 190 190 ASP ASP G . n 
G 1 191 ARG 191 191 191 ARG ARG G . n 
G 1 192 SER 192 192 192 SER SER G . n 
G 1 193 GLY 193 193 193 GLY GLY G . n 
G 1 194 GLY 194 194 194 GLY GLY G . n 
G 1 195 GLY 195 195 195 GLY GLY G . n 
G 1 196 HIS 196 196 196 HIS HIS G . n 
G 1 197 GLY 197 197 197 GLY GLY G . n 
G 1 198 ASN 198 198 198 ASN ASN G . n 
G 1 199 ILE 199 199 199 ILE ILE G . n 
G 1 200 GLY 200 200 200 GLY GLY G . n 
G 1 201 ILE 201 201 201 ILE ILE G . n 
G 1 202 SER 202 202 202 SER SER G . n 
G 1 203 THR 203 203 203 THR THR G . n 
G 1 204 SER 204 204 204 SER SER G . n 
G 1 205 PRO 205 205 205 PRO PRO G . n 
G 1 206 GLU 206 206 206 GLU GLU G . n 
G 1 207 SER 207 207 207 SER SER G . n 
G 1 208 SER 208 208 208 SER SER G . n 
G 1 209 PHE 209 209 209 PHE PHE G . n 
G 1 210 PRO 210 210 210 PRO PRO G . n 
G 1 211 GLY 211 211 211 GLY GLY G . n 
G 1 212 THR 212 212 212 THR THR G . n 
G 1 213 ARG 213 213 213 ARG ARG G . n 
G 1 214 GLU 214 214 214 GLU GLU G . n 
G 1 215 VAL 215 215 215 VAL VAL G . n 
G 1 216 LEU 216 216 216 LEU LEU G . n 
G 1 217 ALA 217 217 217 ALA ALA G . n 
G 1 218 TYR 218 218 218 TYR TYR G . n 
G 1 219 ALA 219 219 219 ALA ALA G . n 
G 1 220 ASN 220 220 220 ASN ASN G . n 
G 1 221 ASP 221 221 221 ASP ASP G . n 
G 1 222 GLN 222 222 222 GLN GLN G . n 
G 1 223 LEU 223 223 223 LEU LEU G . n 
G 1 224 ASP 224 224 224 ASP ASP G . n 
G 1 225 THR 225 225 225 THR THR G . n 
G 1 226 LEU 226 226 226 LEU LEU G . n 
G 1 227 ALA 227 227 227 ALA ALA G . n 
G 1 228 ASP 228 228 228 ASP ASP G . n 
G 1 229 THR 229 229 229 THR THR G . n 
G 1 230 LEU 230 230 230 LEU LEU G . n 
G 1 231 TRP 231 231 231 TRP TRP G . n 
G 1 232 SER 232 232 232 SER SER G . n 
G 1 233 GLN 233 233 233 GLN GLN G . n 
G 1 234 LEU 234 234 234 LEU LEU G . n 
G 1 235 THR 235 235 235 THR THR G . n 
G 1 236 ASP 236 236 236 ASP ASP G . n 
G 1 237 THR 237 237 237 THR THR G . n 
G 1 238 GLN 238 238 238 GLN GLN G . n 
G 1 239 ASN 239 239 239 ASN ASN G . n 
G 1 240 GLN 240 240 240 GLN GLN G . n 
G 1 241 PHE 241 241 241 PHE PHE G . n 
G 1 242 ILE 242 242 242 ILE ILE G . n 
G 1 243 THR 243 243 243 THR THR G . n 
G 1 244 VAL 244 244 244 VAL VAL G . n 
G 1 245 GLU 245 245 245 GLU GLU G . n 
G 1 246 THR 246 246 246 THR THR G . n 
G 1 247 TYR 247 247 247 TYR TYR G . n 
G 1 248 HIS 248 248 248 HIS HIS G . n 
G 1 249 ARG 249 249 249 ARG ARG G . n 
G 1 250 ALA 250 250 250 ALA ALA G . n 
G 1 251 ASP 251 251 251 ASP ASP G . n 
G 1 252 GLN 252 252 252 GLN GLN G . n 
G 1 253 ARG 253 253 253 ARG ARG G . n 
G 1 254 PHE 254 254 254 PHE PHE G . n 
G 1 255 PHE 255 255 255 PHE PHE G . n 
G 1 256 PHE 256 256 256 PHE PHE G . n 
G 1 257 GLU 257 257 257 GLU GLU G . n 
G 1 258 TYR 258 258 258 TYR TYR G . n 
G 1 259 HIS 259 259 259 HIS HIS G . n 
G 1 260 LEU 260 260 260 LEU LEU G . n 
G 1 261 ASP 261 261 261 ASP ASP G . n 
G 1 262 GLY 262 262 262 GLY GLY G . n 
G 1 263 ASP 263 263 263 ASP ASP G . n 
G 1 264 ARG 264 264 264 ARG ARG G . n 
G 1 265 ALA 265 265 265 ALA ALA G . n 
G 1 266 ARG 266 266 266 ARG ARG G . n 
G 1 267 PHE 267 267 267 PHE PHE G . n 
G 1 268 LEU 268 268 268 LEU LEU G . n 
G 1 269 HIS 269 269 269 HIS HIS G . n 
G 1 270 SER 270 270 270 SER SER G . n 
G 1 271 SER 271 271 271 SER SER G . n 
G 1 272 ILE 272 272 272 ILE ILE G . n 
G 1 273 LEU 273 273 273 LEU LEU G . n 
G 1 274 LYS 274 274 274 LYS LYS G . n 
G 1 275 TYR 275 275 275 TYR TYR G . n 
G 1 276 GLU 276 276 276 GLU GLU G . n 
G 1 277 GLN 277 277 277 GLN GLN G . n 
G 1 278 LEU 278 278 ?   ?   ?   G . n 
G 1 279 PRO 279 279 ?   ?   ?   G . n 
G 1 280 GLU 280 280 ?   ?   ?   G . n 
G 1 281 GLY 281 281 ?   ?   ?   G . n 
G 1 282 SER 282 282 ?   ?   ?   G . n 
G 1 283 GLY 283 283 ?   ?   ?   G . n 
G 1 284 GLY 284 284 ?   ?   ?   G . n 
G 1 285 SER 285 285 285 SER SER G . n 
G 1 286 ALA 286 286 286 ALA ALA G . n 
G 1 287 LYS 287 287 ?   ?   ?   G . n 
G 1 288 TRP 288 288 288 TRP TRP G . n 
G 1 289 ILE 289 289 289 ILE ILE G . n 
G 1 290 GLY 290 290 290 GLY GLY G . n 
G 1 291 LEU 291 291 291 LEU LEU G . n 
G 1 292 ASP 292 292 292 ASP ASP G . n 
G 1 293 SER 293 293 293 SER SER G . n 
G 1 294 PRO 294 294 294 PRO PRO G . n 
G 1 295 SER 295 295 295 SER SER G . n 
G 1 296 ARG 296 296 296 ARG ARG G . n 
G 1 297 SER 297 297 297 SER SER G . n 
G 1 298 GLU 298 298 298 GLU GLU G . n 
G 1 299 PHE 299 299 299 PHE PHE G . n 
G 1 300 GLU 300 300 300 GLU GLU G . n 
G 1 301 ALA 301 301 301 ALA ALA G . n 
G 1 302 THR 302 302 302 THR THR G . n 
G 1 303 LEU 303 303 303 LEU LEU G . n 
G 1 304 LYS 304 304 304 LYS LYS G . n 
G 1 305 PRO 305 305 305 PRO PRO G . n 
G 1 306 ALA 306 306 306 ALA ALA G . n 
G 1 307 GLU 307 307 307 GLU GLU G . n 
G 1 308 GLU 308 308 308 GLU GLU G . n 
G 1 309 PHE 309 309 309 PHE PHE G . n 
G 1 310 ILE 310 310 310 ILE ILE G . n 
G 1 311 GLU 311 311 311 GLU GLU G . n 
G 1 312 MET 312 312 312 MET MET G . n 
G 1 313 ILE 313 313 313 ILE ILE G . n 
G 1 314 ARG 314 314 314 ARG ARG G . n 
G 1 315 THR 315 315 315 THR THR G . n 
G 1 316 ILE 316 316 316 ILE ILE G . n 
G 1 317 GLY 317 317 317 GLY GLY G . n 
G 1 318 TYR 318 318 318 TYR TYR G . n 
G 1 319 ARG 319 319 319 ARG ARG G . n 
G 1 320 GLY 320 320 320 GLY GLY G . n 
G 1 321 TYR 321 321 321 TYR TYR G . n 
G 1 322 VAL 322 322 322 VAL VAL G . n 
G 1 323 ASN 323 323 323 ASN ASN G . n 
G 1 324 ILE 324 324 324 ILE ILE G . n 
G 1 325 ASP 325 325 325 ASP ASP G . n 
G 1 326 GLY 326 326 326 GLY GLY G . n 
G 1 327 ILE 327 327 327 ILE ILE G . n 
G 1 328 VAL 328 328 328 VAL VAL G . n 
G 1 329 LEU 329 329 329 LEU LEU G . n 
G 1 330 ASP 330 330 330 ASP ASP G . n 
G 1 331 ASP 331 331 331 ASP ASP G . n 
G 1 332 GLY 332 332 332 GLY GLY G . n 
G 1 333 ARG 333 333 333 ARG ARG G . n 
G 1 334 VAL 334 334 334 VAL VAL G . n 
G 1 335 PHE 335 335 335 PHE PHE G . n 
G 1 336 PHE 336 336 336 PHE PHE G . n 
G 1 337 HIS 337 337 337 HIS HIS G . n 
G 1 338 GLU 338 338 338 GLU GLU G . n 
G 1 339 ILE 339 339 339 ILE ILE G . n 
G 1 340 ASN 340 340 340 ASN ASN G . n 
G 1 341 ALA 341 341 341 ALA ALA G . n 
G 1 342 ARG 342 342 342 ARG ARG G . n 
G 1 343 TRP 343 343 343 TRP TRP G . n 
G 1 344 SER 344 344 344 SER SER G . n 
G 1 345 GLY 345 345 345 GLY GLY G . n 
G 1 346 GLY 346 346 346 GLY GLY G . n 
G 1 347 LEU 347 347 347 LEU LEU G . n 
G 1 348 ILE 348 348 348 ILE ILE G . n 
G 1 349 TYR 349 349 349 TYR TYR G . n 
G 1 350 HIS 350 350 350 HIS HIS G . n 
G 1 351 THR 351 351 351 THR THR G . n 
G 1 352 VAL 352 352 352 VAL VAL G . n 
G 1 353 ALA 353 353 353 ALA ALA G . n 
G 1 354 GLU 354 354 354 GLU GLU G . n 
G 1 355 ARG 355 355 355 ARG ARG G . n 
G 1 356 LEU 356 356 356 LEU LEU G . n 
G 1 357 LEU 357 357 357 LEU LEU G . n 
G 1 358 GLY 358 358 358 GLY GLY G . n 
G 1 359 HIS 359 359 359 HIS HIS G . n 
G 1 360 ASP 360 360 360 ASP ASP G . n 
G 1 361 TYR 361 361 361 TYR TYR G . n 
G 1 362 ALA 362 362 362 ALA ALA G . n 
G 1 363 ARG 363 363 363 ARG ARG G . n 
G 1 364 ASN 364 364 364 ASN ASN G . n 
G 1 365 ASN 365 365 365 ASN ASN G . n 
G 1 366 PHE 366 366 366 PHE PHE G . n 
G 1 367 PHE 367 367 367 PHE PHE G . n 
G 1 368 SER 368 368 368 SER SER G . n 
G 1 369 SER 369 369 369 SER SER G . n 
G 1 370 ILE 370 370 370 ILE ILE G . n 
G 1 371 LEU 371 371 371 LEU LEU G . n 
G 1 372 ASN 372 372 372 ASN ASN G . n 
G 1 373 VAL 373 373 373 VAL VAL G . n 
G 1 374 VAL 374 374 374 VAL VAL G . n 
G 1 375 PRO 375 375 375 PRO PRO G . n 
G 1 376 ALA 376 376 376 ALA ALA G . n 
G 1 377 GLY 377 377 377 GLY GLY G . n 
G 1 378 LEU 378 378 378 LEU LEU G . n 
G 1 379 ALA 379 379 379 ALA ALA G . n 
G 1 380 ASP 380 380 380 ASP ASP G . n 
G 1 381 LEU 381 381 381 LEU LEU G . n 
G 1 382 LEU 382 382 382 LEU LEU G . n 
G 1 383 ARG 383 383 383 ARG ARG G . n 
G 1 384 SER 384 384 384 SER SER G . n 
G 1 385 LEU 385 385 385 LEU LEU G . n 
G 1 386 GLU 386 386 386 GLU GLU G . n 
G 1 387 ARG 387 387 387 ARG ARG G . n 
G 1 388 ALA 388 388 388 ALA ALA G . n 
G 1 389 GLY 389 389 389 GLY GLY G . n 
G 1 390 VAL 390 390 390 VAL VAL G . n 
G 1 391 ARG 391 391 391 ARG ARG G . n 
G 1 392 TYR 392 392 392 TYR TYR G . n 
G 1 393 ASP 393 393 393 ASP ASP G . n 
G 1 394 LYS 394 394 394 LYS LYS G . n 
G 1 395 ASP 395 395 395 ASP ASP G . n 
G 1 396 SER 396 396 396 SER SER G . n 
G 1 397 GLY 397 397 397 GLY GLY G . n 
G 1 398 GLU 398 398 398 GLU GLU G . n 
G 1 399 GLY 399 399 399 GLY GLY G . n 
G 1 400 ALA 400 400 400 ALA ALA G . n 
G 1 401 VAL 401 401 401 VAL VAL G . n 
G 1 402 VAL 402 402 402 VAL VAL G . n 
G 1 403 LEU 403 403 403 LEU LEU G . n 
G 1 404 GLY 404 404 404 GLY GLY G . n 
G 1 405 CYS 405 405 405 CYS CYS G . n 
G 1 406 ASN 406 406 406 ASN ASN G . n 
G 1 407 SER 407 407 407 SER SER G . n 
G 1 408 ASP 408 408 408 ASP ASP G . n 
G 1 409 LEU 409 409 409 LEU LEU G . n 
G 1 410 GLY 410 410 410 GLY GLY G . n 
G 1 411 PRO 411 411 411 PRO PRO G . n 
G 1 412 GLY 412 412 412 GLY GLY G . n 
G 1 413 ALA 413 413 413 ALA ALA G . n 
G 1 414 GLU 414 414 414 GLU GLU G . n 
G 1 415 LEU 415 415 415 LEU LEU G . n 
G 1 416 LEU 416 416 416 LEU LEU G . n 
G 1 417 VAL 417 417 417 VAL VAL G . n 
G 1 418 PHE 418 418 418 PHE PHE G . n 
G 1 419 SER 419 419 419 SER SER G . n 
G 1 420 LYS 420 420 420 LYS LYS G . n 
G 1 421 ASP 421 421 421 ASP ASP G . n 
G 1 422 TRP 422 422 422 TRP TRP G . n 
G 1 423 ASP 423 423 423 ASP ASP G . n 
G 1 424 ARG 424 424 424 ARG ARG G . n 
G 1 425 LEU 425 425 425 LEU LEU G . n 
G 1 426 THR 426 426 426 THR THR G . n 
G 1 427 ALA 427 427 427 ALA ALA G . n 
G 1 428 MET 428 428 428 MET MET G . n 
G 1 429 LYS 429 429 429 LYS LYS G . n 
G 1 430 ASP 430 430 430 ASP ASP G . n 
G 1 431 GLU 431 431 431 GLU GLU G . n 
G 1 432 ILE 432 432 432 ILE ILE G . n 
G 1 433 ALA 433 433 433 ALA ALA G . n 
G 1 434 THR 434 434 434 THR THR G . n 
G 1 435 THR 435 435 435 THR THR G . n 
G 1 436 ALA 436 436 436 ALA ALA G . n 
G 1 437 GLY 437 437 437 GLY GLY G . n 
G 1 438 THR 438 438 438 THR THR G . n 
G 1 439 LEU 439 439 439 LEU LEU G . n 
G 1 440 SER 440 440 440 SER SER G . n 
G 1 441 LEU 441 441 ?   ?   ?   G . n 
G 1 442 GLU 442 442 ?   ?   ?   G . n 
G 1 443 HIS 443 443 ?   ?   ?   G . n 
G 1 444 HIS 444 444 ?   ?   ?   G . n 
G 1 445 HIS 445 445 ?   ?   ?   G . n 
G 1 446 HIS 446 446 ?   ?   ?   G . n 
G 1 447 HIS 447 447 ?   ?   ?   G . n 
G 1 448 HIS 448 448 ?   ?   ?   G . n 
H 1 1   MET 1   1   ?   ?   ?   H . n 
H 1 2   PRO 2   2   2   PRO PRO H . n 
H 1 3   LYS 3   3   3   LYS LYS H . n 
H 1 4   ILE 4   4   4   ILE ILE H . n 
H 1 5   ILE 5   5   5   ILE ILE H . n 
H 1 6   LEU 6   6   6   LEU LEU H . n 
H 1 7   PRO 7   7   7   PRO PRO H . n 
H 1 8   ASN 8   8   8   ASN ASN H . n 
H 1 9   PHE 9   9   9   PHE PHE H . n 
H 1 10  ARG 10  10  10  ARG ARG H . n 
H 1 11  ALA 11  11  ?   ?   ?   H . n 
H 1 12  ASP 12  12  ?   ?   ?   H . n 
H 1 13  TYR 13  13  ?   ?   ?   H . n 
H 1 14  SER 14  14  ?   ?   ?   H . n 
H 1 15  GLU 15  15  ?   ?   ?   H . n 
H 1 16  GLN 16  16  ?   ?   ?   H . n 
H 1 17  VAL 17  17  ?   ?   ?   H . n 
H 1 18  ARG 18  18  ?   ?   ?   H . n 
H 1 19  ASP 19  19  ?   ?   ?   H . n 
H 1 20  TRP 20  20  ?   ?   ?   H . n 
H 1 21  LEU 21  21  ?   ?   ?   H . n 
H 1 22  GLY 22  22  ?   ?   ?   H . n 
H 1 23  ILE 23  23  ?   ?   ?   H . n 
H 1 24  SER 24  24  ?   ?   ?   H . n 
H 1 25  ASP 25  25  ?   ?   ?   H . n 
H 1 26  ALA 26  26  ?   ?   ?   H . n 
H 1 27  THR 27  27  ?   ?   ?   H . n 
H 1 28  ALA 28  28  ?   ?   ?   H . n 
H 1 29  SER 29  29  29  SER SER H . n 
H 1 30  SER 30  30  30  SER SER H . n 
H 1 31  THR 31  31  31  THR THR H . n 
H 1 32  ASP 32  32  32  ASP ASP H . n 
H 1 33  THR 33  33  33  THR THR H . n 
H 1 34  THR 34  34  34  THR THR H . n 
H 1 35  ALA 35  35  35  ALA ALA H . n 
H 1 36  ARG 36  36  36  ARG ARG H . n 
H 1 37  PHE 37  37  37  PHE PHE H . n 
H 1 38  LEU 38  38  38  LEU LEU H . n 
H 1 39  TRP 39  39  39  TRP TRP H . n 
H 1 40  HIS 40  40  40  HIS HIS H . n 
H 1 41  ALA 41  41  41  ALA ALA H . n 
H 1 42  GLU 42  42  42  GLU GLU H . n 
H 1 43  ASP 43  43  43  ASP ASP H . n 
H 1 44  GLY 44  44  44  GLY GLY H . n 
H 1 45  ASP 45  45  45  ASP ASP H . n 
H 1 46  VAL 46  46  46  VAL VAL H . n 
H 1 47  LEU 47  47  47  LEU LEU H . n 
H 1 48  VAL 48  48  48  VAL VAL H . n 
H 1 49  ILE 49  49  49  ILE ILE H . n 
H 1 50  PRO 50  50  50  PRO PRO H . n 
H 1 51  ASP 51  51  51  ASP ASP H . n 
H 1 52  THR 52  52  52  THR THR H . n 
H 1 53  VAL 53  53  53  VAL VAL H . n 
H 1 54  ASP 54  54  54  ASP ASP H . n 
H 1 55  PRO 55  55  55  PRO PRO H . n 
H 1 56  ASP 56  56  56  ASP ASP H . n 
H 1 57  PHE 57  57  57  PHE PHE H . n 
H 1 58  PRO 58  58  58  PRO PRO H . n 
H 1 59  GLY 59  59  59  GLY GLY H . n 
H 1 60  TYR 60  60  60  TYR TYR H . n 
H 1 61  VAL 61  61  61  VAL VAL H . n 
H 1 62  ALA 62  62  62  ALA ALA H . n 
H 1 63  ASP 63  63  63  ASP ASP H . n 
H 1 64  THR 64  64  64  THR THR H . n 
H 1 65  LEU 65  65  65  LEU LEU H . n 
H 1 66  GLY 66  66  66  GLY GLY H . n 
H 1 67  ILE 67  67  67  ILE ILE H . n 
H 1 68  ASP 68  68  68  ASP ASP H . n 
H 1 69  GLY 69  69  69  GLY GLY H . n 
H 1 70  THR 70  70  70  THR THR H . n 
H 1 71  SER 71  71  71  SER SER H . n 
H 1 72  VAL 72  72  72  VAL VAL H . n 
H 1 73  HIS 73  73  73  HIS HIS H . n 
H 1 74  VAL 74  74  74  VAL VAL H . n 
H 1 75  GLU 75  75  75  GLU GLU H . n 
H 1 76  ARG 76  76  76  ARG ARG H . n 
H 1 77  THR 77  77  77  THR THR H . n 
H 1 78  GLN 78  78  78  GLN GLN H . n 
H 1 79  THR 79  79  79  THR THR H . n 
H 1 80  PRO 80  80  80  PRO PRO H . n 
H 1 81  LEU 81  81  81  LEU LEU H . n 
H 1 82  SER 82  82  82  SER SER H . n 
H 1 83  GLU 83  83  83  GLU GLU H . n 
H 1 84  ALA 84  84  84  ALA ALA H . n 
H 1 85  VAL 85  85  85  VAL VAL H . n 
H 1 86  LEU 86  86  86  LEU LEU H . n 
H 1 87  GLN 87  87  87  GLN GLN H . n 
H 1 88  ASP 88  88  88  ASP ASP H . n 
H 1 89  PRO 89  89  89  PRO PRO H . n 
H 1 90  GLU 90  90  90  GLU GLU H . n 
H 1 91  PHE 91  91  91  PHE PHE H . n 
H 1 92  ILE 92  92  92  ILE ILE H . n 
H 1 93  ASP 93  93  93  ASP ASP H . n 
H 1 94  ARG 94  94  94  ARG ARG H . n 
H 1 95  LEU 95  95  95  LEU LEU H . n 
H 1 96  ALA 96  96  96  ALA ALA H . n 
H 1 97  ALA 97  97  97  ALA ALA H . n 
H 1 98  HIS 98  98  98  HIS HIS H . n 
H 1 99  THR 99  99  99  THR THR H . n 
H 1 100 GLY 100 100 100 GLY GLY H . n 
H 1 101 THR 101 101 101 THR THR H . n 
H 1 102 GLY 102 102 102 GLY GLY H . n 
H 1 103 ALA 103 103 103 ALA ALA H . n 
H 1 104 GLY 104 104 104 GLY GLY H . n 
H 1 105 TRP 105 105 105 TRP TRP H . n 
H 1 106 SER 106 106 106 SER SER H . n 
H 1 107 LEU 107 107 107 LEU LEU H . n 
H 1 108 PHE 108 108 108 PHE PHE H . n 
H 1 109 PRO 109 109 109 PRO PRO H . n 
H 1 110 CYS 110 110 110 CYS CYS H . n 
H 1 111 VAL 111 111 111 VAL VAL H . n 
H 1 112 SER 112 112 112 SER SER H . n 
H 1 113 THR 113 113 113 THR THR H . n 
H 1 114 ARG 114 114 114 ARG ARG H . n 
H 1 115 ALA 115 115 115 ALA ALA H . n 
H 1 116 ALA 116 116 116 ALA ALA H . n 
H 1 117 ALA 117 117 117 ALA ALA H . n 
H 1 118 GLN 118 118 118 GLN GLN H . n 
H 1 119 LEU 119 119 119 LEU LEU H . n 
H 1 120 THR 120 120 120 THR THR H . n 
H 1 121 ARG 121 121 121 ARG ARG H . n 
H 1 122 LYS 122 122 122 LYS LYS H . n 
H 1 123 LEU 123 123 123 LEU LEU H . n 
H 1 124 ASN 124 124 124 ASN ASN H . n 
H 1 125 VAL 125 125 125 VAL VAL H . n 
H 1 126 ALA 126 126 126 ALA ALA H . n 
H 1 127 ALA 127 127 127 ALA ALA H . n 
H 1 128 LEU 128 128 128 LEU LEU H . n 
H 1 129 ASP 129 129 129 ASP ASP H . n 
H 1 130 GLY 130 130 130 GLY GLY H . n 
H 1 131 TYR 131 131 131 TYR TYR H . n 
H 1 132 GLU 132 132 132 GLU GLU H . n 
H 1 133 PHE 133 133 133 PHE PHE H . n 
H 1 134 ALA 134 134 134 ALA ALA H . n 
H 1 135 MET 135 135 135 MET MET H . n 
H 1 136 GLN 136 136 136 GLN GLN H . n 
H 1 137 ASN 137 137 137 ASN ASN H . n 
H 1 138 GLY 138 138 138 GLY GLY H . n 
H 1 139 ILE 139 139 139 ILE ILE H . n 
H 1 140 ASP 140 140 140 ASP ASP H . n 
H 1 141 LEU 141 141 141 LEU LEU H . n 
H 1 142 LEU 142 142 142 LEU LEU H . n 
H 1 143 ASN 143 143 143 ASN ASN H . n 
H 1 144 MET 144 144 144 MET MET H . n 
H 1 145 LYS 145 145 145 LYS LYS H . n 
H 1 146 SER 146 146 146 SER SER H . n 
H 1 147 THR 147 147 147 THR THR H . n 
H 1 148 PHE 148 148 148 PHE PHE H . n 
H 1 149 ARG 149 149 149 ARG ARG H . n 
H 1 150 ARG 150 150 150 ARG ARG H . n 
H 1 151 LEU 151 151 151 LEU LEU H . n 
H 1 152 ALA 152 152 152 ALA ALA H . n 
H 1 153 ALA 153 153 153 ALA ALA H . n 
H 1 154 GLY 154 154 154 GLY GLY H . n 
H 1 155 LEU 155 155 155 LEU LEU H . n 
H 1 156 GLY 156 156 156 GLY GLY H . n 
H 1 157 THR 157 157 157 THR THR H . n 
H 1 158 PRO 158 158 158 PRO PRO H . n 
H 1 159 LEU 159 159 159 LEU LEU H . n 
H 1 160 THR 160 160 160 THR THR H . n 
H 1 161 ASP 161 161 161 ASP ASP H . n 
H 1 162 GLY 162 162 162 GLY GLY H . n 
H 1 163 VAL 163 163 163 VAL VAL H . n 
H 1 164 VAL 164 164 164 VAL VAL H . n 
H 1 165 ALA 165 165 165 ALA ALA H . n 
H 1 166 ARG 166 166 166 ARG ARG H . n 
H 1 167 GLY 167 167 167 GLY GLY H . n 
H 1 168 PRO 168 168 168 PRO PRO H . n 
H 1 169 ALA 169 169 169 ALA ALA H . n 
H 1 170 GLU 170 170 170 GLU GLU H . n 
H 1 171 VAL 171 171 171 VAL VAL H . n 
H 1 172 ARG 172 172 172 ARG ARG H . n 
H 1 173 SER 173 173 173 SER SER H . n 
H 1 174 ALA 174 174 174 ALA ALA H . n 
H 1 175 ILE 175 175 175 ILE ILE H . n 
H 1 176 GLN 176 176 176 GLN GLN H . n 
H 1 177 GLU 177 177 177 GLU GLU H . n 
H 1 178 LEU 178 178 178 LEU LEU H . n 
H 1 179 ILE 179 179 179 ILE ILE H . n 
H 1 180 ALA 180 180 180 ALA ALA H . n 
H 1 181 GLU 181 181 181 GLU GLU H . n 
H 1 182 THR 182 182 182 THR THR H . n 
H 1 183 GLY 183 183 183 GLY GLY H . n 
H 1 184 MET 184 184 184 MET MET H . n 
H 1 185 VAL 185 185 185 VAL VAL H . n 
H 1 186 ILE 186 186 186 ILE ILE H . n 
H 1 187 ALA 187 187 187 ALA ALA H . n 
H 1 188 LYS 188 188 188 LYS LYS H . n 
H 1 189 GLN 189 189 189 GLN GLN H . n 
H 1 190 ASP 190 190 190 ASP ASP H . n 
H 1 191 ARG 191 191 191 ARG ARG H . n 
H 1 192 SER 192 192 192 SER SER H . n 
H 1 193 GLY 193 193 193 GLY GLY H . n 
H 1 194 GLY 194 194 194 GLY GLY H . n 
H 1 195 GLY 195 195 195 GLY GLY H . n 
H 1 196 HIS 196 196 196 HIS HIS H . n 
H 1 197 GLY 197 197 197 GLY GLY H . n 
H 1 198 ASN 198 198 198 ASN ASN H . n 
H 1 199 ILE 199 199 199 ILE ILE H . n 
H 1 200 GLY 200 200 200 GLY GLY H . n 
H 1 201 ILE 201 201 201 ILE ILE H . n 
H 1 202 SER 202 202 202 SER SER H . n 
H 1 203 THR 203 203 203 THR THR H . n 
H 1 204 SER 204 204 204 SER SER H . n 
H 1 205 PRO 205 205 205 PRO PRO H . n 
H 1 206 GLU 206 206 206 GLU GLU H . n 
H 1 207 SER 207 207 207 SER SER H . n 
H 1 208 SER 208 208 208 SER SER H . n 
H 1 209 PHE 209 209 209 PHE PHE H . n 
H 1 210 PRO 210 210 210 PRO PRO H . n 
H 1 211 GLY 211 211 211 GLY GLY H . n 
H 1 212 THR 212 212 212 THR THR H . n 
H 1 213 ARG 213 213 213 ARG ARG H . n 
H 1 214 GLU 214 214 214 GLU GLU H . n 
H 1 215 VAL 215 215 215 VAL VAL H . n 
H 1 216 LEU 216 216 216 LEU LEU H . n 
H 1 217 ALA 217 217 217 ALA ALA H . n 
H 1 218 TYR 218 218 218 TYR TYR H . n 
H 1 219 ALA 219 219 219 ALA ALA H . n 
H 1 220 ASN 220 220 220 ASN ASN H . n 
H 1 221 ASP 221 221 221 ASP ASP H . n 
H 1 222 GLN 222 222 222 GLN GLN H . n 
H 1 223 LEU 223 223 223 LEU LEU H . n 
H 1 224 ASP 224 224 224 ASP ASP H . n 
H 1 225 THR 225 225 225 THR THR H . n 
H 1 226 LEU 226 226 226 LEU LEU H . n 
H 1 227 ALA 227 227 227 ALA ALA H . n 
H 1 228 ASP 228 228 228 ASP ASP H . n 
H 1 229 THR 229 229 229 THR THR H . n 
H 1 230 LEU 230 230 230 LEU LEU H . n 
H 1 231 TRP 231 231 231 TRP TRP H . n 
H 1 232 SER 232 232 232 SER SER H . n 
H 1 233 GLN 233 233 233 GLN GLN H . n 
H 1 234 LEU 234 234 234 LEU LEU H . n 
H 1 235 THR 235 235 235 THR THR H . n 
H 1 236 ASP 236 236 236 ASP ASP H . n 
H 1 237 THR 237 237 237 THR THR H . n 
H 1 238 GLN 238 238 238 GLN GLN H . n 
H 1 239 ASN 239 239 239 ASN ASN H . n 
H 1 240 GLN 240 240 240 GLN GLN H . n 
H 1 241 PHE 241 241 241 PHE PHE H . n 
H 1 242 ILE 242 242 242 ILE ILE H . n 
H 1 243 THR 243 243 243 THR THR H . n 
H 1 244 VAL 244 244 244 VAL VAL H . n 
H 1 245 GLU 245 245 245 GLU GLU H . n 
H 1 246 THR 246 246 246 THR THR H . n 
H 1 247 TYR 247 247 247 TYR TYR H . n 
H 1 248 HIS 248 248 248 HIS HIS H . n 
H 1 249 ARG 249 249 249 ARG ARG H . n 
H 1 250 ALA 250 250 250 ALA ALA H . n 
H 1 251 ASP 251 251 251 ASP ASP H . n 
H 1 252 GLN 252 252 252 GLN GLN H . n 
H 1 253 ARG 253 253 253 ARG ARG H . n 
H 1 254 PHE 254 254 254 PHE PHE H . n 
H 1 255 PHE 255 255 255 PHE PHE H . n 
H 1 256 PHE 256 256 256 PHE PHE H . n 
H 1 257 GLU 257 257 257 GLU GLU H . n 
H 1 258 TYR 258 258 258 TYR TYR H . n 
H 1 259 HIS 259 259 259 HIS HIS H . n 
H 1 260 LEU 260 260 260 LEU LEU H . n 
H 1 261 ASP 261 261 261 ASP ASP H . n 
H 1 262 GLY 262 262 262 GLY GLY H . n 
H 1 263 ASP 263 263 263 ASP ASP H . n 
H 1 264 ARG 264 264 264 ARG ARG H . n 
H 1 265 ALA 265 265 265 ALA ALA H . n 
H 1 266 ARG 266 266 266 ARG ARG H . n 
H 1 267 PHE 267 267 267 PHE PHE H . n 
H 1 268 LEU 268 268 268 LEU LEU H . n 
H 1 269 HIS 269 269 269 HIS HIS H . n 
H 1 270 SER 270 270 270 SER SER H . n 
H 1 271 SER 271 271 271 SER SER H . n 
H 1 272 ILE 272 272 272 ILE ILE H . n 
H 1 273 LEU 273 273 273 LEU LEU H . n 
H 1 274 LYS 274 274 274 LYS LYS H . n 
H 1 275 TYR 275 275 275 TYR TYR H . n 
H 1 276 GLU 276 276 276 GLU GLU H . n 
H 1 277 GLN 277 277 277 GLN GLN H . n 
H 1 278 LEU 278 278 ?   ?   ?   H . n 
H 1 279 PRO 279 279 ?   ?   ?   H . n 
H 1 280 GLU 280 280 ?   ?   ?   H . n 
H 1 281 GLY 281 281 ?   ?   ?   H . n 
H 1 282 SER 282 282 ?   ?   ?   H . n 
H 1 283 GLY 283 283 ?   ?   ?   H . n 
H 1 284 GLY 284 284 ?   ?   ?   H . n 
H 1 285 SER 285 285 285 SER SER H . n 
H 1 286 ALA 286 286 286 ALA ALA H . n 
H 1 287 LYS 287 287 287 LYS LYS H . n 
H 1 288 TRP 288 288 288 TRP TRP H . n 
H 1 289 ILE 289 289 289 ILE ILE H . n 
H 1 290 GLY 290 290 290 GLY GLY H . n 
H 1 291 LEU 291 291 291 LEU LEU H . n 
H 1 292 ASP 292 292 292 ASP ASP H . n 
H 1 293 SER 293 293 293 SER SER H . n 
H 1 294 PRO 294 294 294 PRO PRO H . n 
H 1 295 SER 295 295 295 SER SER H . n 
H 1 296 ARG 296 296 296 ARG ARG H . n 
H 1 297 SER 297 297 297 SER SER H . n 
H 1 298 GLU 298 298 298 GLU GLU H . n 
H 1 299 PHE 299 299 299 PHE PHE H . n 
H 1 300 GLU 300 300 300 GLU GLU H . n 
H 1 301 ALA 301 301 301 ALA ALA H . n 
H 1 302 THR 302 302 302 THR THR H . n 
H 1 303 LEU 303 303 303 LEU LEU H . n 
H 1 304 LYS 304 304 304 LYS LYS H . n 
H 1 305 PRO 305 305 305 PRO PRO H . n 
H 1 306 ALA 306 306 306 ALA ALA H . n 
H 1 307 GLU 307 307 307 GLU GLU H . n 
H 1 308 GLU 308 308 308 GLU GLU H . n 
H 1 309 PHE 309 309 309 PHE PHE H . n 
H 1 310 ILE 310 310 310 ILE ILE H . n 
H 1 311 GLU 311 311 311 GLU GLU H . n 
H 1 312 MET 312 312 312 MET MET H . n 
H 1 313 ILE 313 313 313 ILE ILE H . n 
H 1 314 ARG 314 314 314 ARG ARG H . n 
H 1 315 THR 315 315 315 THR THR H . n 
H 1 316 ILE 316 316 316 ILE ILE H . n 
H 1 317 GLY 317 317 317 GLY GLY H . n 
H 1 318 TYR 318 318 318 TYR TYR H . n 
H 1 319 ARG 319 319 319 ARG ARG H . n 
H 1 320 GLY 320 320 320 GLY GLY H . n 
H 1 321 TYR 321 321 321 TYR TYR H . n 
H 1 322 VAL 322 322 322 VAL VAL H . n 
H 1 323 ASN 323 323 323 ASN ASN H . n 
H 1 324 ILE 324 324 324 ILE ILE H . n 
H 1 325 ASP 325 325 325 ASP ASP H . n 
H 1 326 GLY 326 326 326 GLY GLY H . n 
H 1 327 ILE 327 327 327 ILE ILE H . n 
H 1 328 VAL 328 328 328 VAL VAL H . n 
H 1 329 LEU 329 329 329 LEU LEU H . n 
H 1 330 ASP 330 330 330 ASP ASP H . n 
H 1 331 ASP 331 331 331 ASP ASP H . n 
H 1 332 GLY 332 332 332 GLY GLY H . n 
H 1 333 ARG 333 333 333 ARG ARG H . n 
H 1 334 VAL 334 334 334 VAL VAL H . n 
H 1 335 PHE 335 335 335 PHE PHE H . n 
H 1 336 PHE 336 336 336 PHE PHE H . n 
H 1 337 HIS 337 337 337 HIS HIS H . n 
H 1 338 GLU 338 338 338 GLU GLU H . n 
H 1 339 ILE 339 339 339 ILE ILE H . n 
H 1 340 ASN 340 340 340 ASN ASN H . n 
H 1 341 ALA 341 341 341 ALA ALA H . n 
H 1 342 ARG 342 342 342 ARG ARG H . n 
H 1 343 TRP 343 343 343 TRP TRP H . n 
H 1 344 SER 344 344 344 SER SER H . n 
H 1 345 GLY 345 345 345 GLY GLY H . n 
H 1 346 GLY 346 346 346 GLY GLY H . n 
H 1 347 LEU 347 347 347 LEU LEU H . n 
H 1 348 ILE 348 348 348 ILE ILE H . n 
H 1 349 TYR 349 349 349 TYR TYR H . n 
H 1 350 HIS 350 350 350 HIS HIS H . n 
H 1 351 THR 351 351 351 THR THR H . n 
H 1 352 VAL 352 352 352 VAL VAL H . n 
H 1 353 ALA 353 353 353 ALA ALA H . n 
H 1 354 GLU 354 354 354 GLU GLU H . n 
H 1 355 ARG 355 355 355 ARG ARG H . n 
H 1 356 LEU 356 356 356 LEU LEU H . n 
H 1 357 LEU 357 357 357 LEU LEU H . n 
H 1 358 GLY 358 358 358 GLY GLY H . n 
H 1 359 HIS 359 359 359 HIS HIS H . n 
H 1 360 ASP 360 360 360 ASP ASP H . n 
H 1 361 TYR 361 361 361 TYR TYR H . n 
H 1 362 ALA 362 362 362 ALA ALA H . n 
H 1 363 ARG 363 363 363 ARG ARG H . n 
H 1 364 ASN 364 364 364 ASN ASN H . n 
H 1 365 ASN 365 365 365 ASN ASN H . n 
H 1 366 PHE 366 366 366 PHE PHE H . n 
H 1 367 PHE 367 367 367 PHE PHE H . n 
H 1 368 SER 368 368 368 SER SER H . n 
H 1 369 SER 369 369 369 SER SER H . n 
H 1 370 ILE 370 370 370 ILE ILE H . n 
H 1 371 LEU 371 371 371 LEU LEU H . n 
H 1 372 ASN 372 372 372 ASN ASN H . n 
H 1 373 VAL 373 373 373 VAL VAL H . n 
H 1 374 VAL 374 374 374 VAL VAL H . n 
H 1 375 PRO 375 375 375 PRO PRO H . n 
H 1 376 ALA 376 376 376 ALA ALA H . n 
H 1 377 GLY 377 377 377 GLY GLY H . n 
H 1 378 LEU 378 378 378 LEU LEU H . n 
H 1 379 ALA 379 379 379 ALA ALA H . n 
H 1 380 ASP 380 380 380 ASP ASP H . n 
H 1 381 LEU 381 381 381 LEU LEU H . n 
H 1 382 LEU 382 382 382 LEU LEU H . n 
H 1 383 ARG 383 383 383 ARG ARG H . n 
H 1 384 SER 384 384 384 SER SER H . n 
H 1 385 LEU 385 385 385 LEU LEU H . n 
H 1 386 GLU 386 386 386 GLU GLU H . n 
H 1 387 ARG 387 387 387 ARG ARG H . n 
H 1 388 ALA 388 388 388 ALA ALA H . n 
H 1 389 GLY 389 389 389 GLY GLY H . n 
H 1 390 VAL 390 390 390 VAL VAL H . n 
H 1 391 ARG 391 391 391 ARG ARG H . n 
H 1 392 TYR 392 392 392 TYR TYR H . n 
H 1 393 ASP 393 393 393 ASP ASP H . n 
H 1 394 LYS 394 394 394 LYS LYS H . n 
H 1 395 ASP 395 395 395 ASP ASP H . n 
H 1 396 SER 396 396 396 SER SER H . n 
H 1 397 GLY 397 397 397 GLY GLY H . n 
H 1 398 GLU 398 398 398 GLU GLU H . n 
H 1 399 GLY 399 399 399 GLY GLY H . n 
H 1 400 ALA 400 400 400 ALA ALA H . n 
H 1 401 VAL 401 401 401 VAL VAL H . n 
H 1 402 VAL 402 402 402 VAL VAL H . n 
H 1 403 LEU 403 403 403 LEU LEU H . n 
H 1 404 GLY 404 404 404 GLY GLY H . n 
H 1 405 CYS 405 405 405 CYS CYS H . n 
H 1 406 ASN 406 406 406 ASN ASN H . n 
H 1 407 SER 407 407 407 SER SER H . n 
H 1 408 ASP 408 408 408 ASP ASP H . n 
H 1 409 LEU 409 409 409 LEU LEU H . n 
H 1 410 GLY 410 410 410 GLY GLY H . n 
H 1 411 PRO 411 411 411 PRO PRO H . n 
H 1 412 GLY 412 412 412 GLY GLY H . n 
H 1 413 ALA 413 413 413 ALA ALA H . n 
H 1 414 GLU 414 414 414 GLU GLU H . n 
H 1 415 LEU 415 415 415 LEU LEU H . n 
H 1 416 LEU 416 416 416 LEU LEU H . n 
H 1 417 VAL 417 417 417 VAL VAL H . n 
H 1 418 PHE 418 418 418 PHE PHE H . n 
H 1 419 SER 419 419 419 SER SER H . n 
H 1 420 LYS 420 420 420 LYS LYS H . n 
H 1 421 ASP 421 421 421 ASP ASP H . n 
H 1 422 TRP 422 422 422 TRP TRP H . n 
H 1 423 ASP 423 423 423 ASP ASP H . n 
H 1 424 ARG 424 424 424 ARG ARG H . n 
H 1 425 LEU 425 425 425 LEU LEU H . n 
H 1 426 THR 426 426 426 THR THR H . n 
H 1 427 ALA 427 427 427 ALA ALA H . n 
H 1 428 MET 428 428 428 MET MET H . n 
H 1 429 LYS 429 429 429 LYS LYS H . n 
H 1 430 ASP 430 430 430 ASP ASP H . n 
H 1 431 GLU 431 431 431 GLU GLU H . n 
H 1 432 ILE 432 432 432 ILE ILE H . n 
H 1 433 ALA 433 433 433 ALA ALA H . n 
H 1 434 THR 434 434 434 THR THR H . n 
H 1 435 THR 435 435 435 THR THR H . n 
H 1 436 ALA 436 436 436 ALA ALA H . n 
H 1 437 GLY 437 437 437 GLY GLY H . n 
H 1 438 THR 438 438 438 THR THR H . n 
H 1 439 LEU 439 439 439 LEU LEU H . n 
H 1 440 SER 440 440 440 SER SER H . n 
H 1 441 LEU 441 441 ?   ?   ?   H . n 
H 1 442 GLU 442 442 ?   ?   ?   H . n 
H 1 443 HIS 443 443 ?   ?   ?   H . n 
H 1 444 HIS 444 444 ?   ?   ?   H . n 
H 1 445 HIS 445 445 ?   ?   ?   H . n 
H 1 446 HIS 446 446 ?   ?   ?   H . n 
H 1 447 HIS 447 447 ?   ?   ?   H . n 
H 1 448 HIS 448 448 ?   ?   ?   H . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
I 2 HOH 1   501 1078 HOH HOH A . 
I 2 HOH 2   502 549  HOH HOH A . 
I 2 HOH 3   503 888  HOH HOH A . 
I 2 HOH 4   504 1107 HOH HOH A . 
I 2 HOH 5   505 764  HOH HOH A . 
I 2 HOH 6   506 808  HOH HOH A . 
I 2 HOH 7   507 751  HOH HOH A . 
I 2 HOH 8   508 1104 HOH HOH A . 
I 2 HOH 9   509 713  HOH HOH A . 
I 2 HOH 10  510 287  HOH HOH A . 
I 2 HOH 11  511 801  HOH HOH A . 
I 2 HOH 12  512 543  HOH HOH A . 
I 2 HOH 13  513 1103 HOH HOH A . 
I 2 HOH 14  514 805  HOH HOH A . 
I 2 HOH 15  515 54   HOH HOH A . 
I 2 HOH 16  516 31   HOH HOH A . 
I 2 HOH 17  517 201  HOH HOH A . 
I 2 HOH 18  518 765  HOH HOH A . 
I 2 HOH 19  519 343  HOH HOH A . 
I 2 HOH 20  520 527  HOH HOH A . 
I 2 HOH 21  521 316  HOH HOH A . 
I 2 HOH 22  522 704  HOH HOH A . 
I 2 HOH 23  523 1016 HOH HOH A . 
I 2 HOH 24  524 490  HOH HOH A . 
I 2 HOH 25  525 694  HOH HOH A . 
I 2 HOH 26  526 1366 HOH HOH A . 
I 2 HOH 27  527 861  HOH HOH A . 
I 2 HOH 28  528 414  HOH HOH A . 
I 2 HOH 29  529 139  HOH HOH A . 
I 2 HOH 30  530 749  HOH HOH A . 
I 2 HOH 31  531 1062 HOH HOH A . 
I 2 HOH 32  532 445  HOH HOH A . 
I 2 HOH 33  533 1429 HOH HOH A . 
I 2 HOH 34  534 307  HOH HOH A . 
I 2 HOH 35  535 61   HOH HOH A . 
I 2 HOH 36  536 141  HOH HOH A . 
I 2 HOH 37  537 616  HOH HOH A . 
I 2 HOH 38  538 283  HOH HOH A . 
I 2 HOH 39  539 1289 HOH HOH A . 
I 2 HOH 40  540 166  HOH HOH A . 
I 2 HOH 41  541 577  HOH HOH A . 
I 2 HOH 42  542 1134 HOH HOH A . 
I 2 HOH 43  543 608  HOH HOH A . 
I 2 HOH 44  544 12   HOH HOH A . 
I 2 HOH 45  545 813  HOH HOH A . 
I 2 HOH 46  546 650  HOH HOH A . 
I 2 HOH 47  547 63   HOH HOH A . 
I 2 HOH 48  548 668  HOH HOH A . 
I 2 HOH 49  549 14   HOH HOH A . 
I 2 HOH 50  550 94   HOH HOH A . 
I 2 HOH 51  551 16   HOH HOH A . 
I 2 HOH 52  552 1413 HOH HOH A . 
I 2 HOH 53  553 1188 HOH HOH A . 
I 2 HOH 54  554 586  HOH HOH A . 
I 2 HOH 55  555 910  HOH HOH A . 
I 2 HOH 56  556 1033 HOH HOH A . 
I 2 HOH 57  557 252  HOH HOH A . 
I 2 HOH 58  558 575  HOH HOH A . 
I 2 HOH 59  559 1417 HOH HOH A . 
I 2 HOH 60  560 97   HOH HOH A . 
I 2 HOH 61  561 701  HOH HOH A . 
I 2 HOH 62  562 274  HOH HOH A . 
I 2 HOH 63  563 619  HOH HOH A . 
I 2 HOH 64  564 454  HOH HOH A . 
I 2 HOH 65  565 631  HOH HOH A . 
I 2 HOH 66  566 247  HOH HOH A . 
I 2 HOH 67  567 315  HOH HOH A . 
I 2 HOH 68  568 481  HOH HOH A . 
I 2 HOH 69  569 52   HOH HOH A . 
I 2 HOH 70  570 172  HOH HOH A . 
I 2 HOH 71  571 540  HOH HOH A . 
I 2 HOH 72  572 973  HOH HOH A . 
I 2 HOH 73  573 1054 HOH HOH A . 
I 2 HOH 74  574 1274 HOH HOH A . 
I 2 HOH 75  575 137  HOH HOH A . 
I 2 HOH 76  576 1260 HOH HOH A . 
I 2 HOH 77  577 879  HOH HOH A . 
I 2 HOH 78  578 242  HOH HOH A . 
I 2 HOH 79  579 272  HOH HOH A . 
I 2 HOH 80  580 326  HOH HOH A . 
I 2 HOH 81  581 1007 HOH HOH A . 
I 2 HOH 82  582 1225 HOH HOH A . 
I 2 HOH 83  583 385  HOH HOH A . 
I 2 HOH 84  584 24   HOH HOH A . 
I 2 HOH 85  585 1446 HOH HOH A . 
I 2 HOH 86  586 152  HOH HOH A . 
I 2 HOH 87  587 192  HOH HOH A . 
I 2 HOH 88  588 555  HOH HOH A . 
I 2 HOH 89  589 11   HOH HOH A . 
I 2 HOH 90  590 907  HOH HOH A . 
I 2 HOH 91  591 587  HOH HOH A . 
I 2 HOH 92  592 226  HOH HOH A . 
I 2 HOH 93  593 171  HOH HOH A . 
I 2 HOH 94  594 1252 HOH HOH A . 
I 2 HOH 95  595 89   HOH HOH A . 
I 2 HOH 96  596 1010 HOH HOH A . 
I 2 HOH 97  597 593  HOH HOH A . 
I 2 HOH 98  598 1148 HOH HOH A . 
I 2 HOH 99  599 389  HOH HOH A . 
I 2 HOH 100 600 1012 HOH HOH A . 
I 2 HOH 101 601 930  HOH HOH A . 
I 2 HOH 102 602 942  HOH HOH A . 
I 2 HOH 103 603 840  HOH HOH A . 
I 2 HOH 104 604 516  HOH HOH A . 
I 2 HOH 105 605 995  HOH HOH A . 
I 2 HOH 106 606 821  HOH HOH A . 
I 2 HOH 107 607 599  HOH HOH A . 
I 2 HOH 108 608 1093 HOH HOH A . 
I 2 HOH 109 609 961  HOH HOH A . 
I 2 HOH 110 610 488  HOH HOH A . 
I 2 HOH 111 611 238  HOH HOH A . 
I 2 HOH 112 612 267  HOH HOH A . 
I 2 HOH 113 613 476  HOH HOH A . 
I 2 HOH 114 614 703  HOH HOH A . 
I 2 HOH 115 615 537  HOH HOH A . 
I 2 HOH 116 616 378  HOH HOH A . 
I 2 HOH 117 617 872  HOH HOH A . 
I 2 HOH 118 618 478  HOH HOH A . 
I 2 HOH 119 619 667  HOH HOH A . 
I 2 HOH 120 620 1381 HOH HOH A . 
I 2 HOH 121 621 822  HOH HOH A . 
I 2 HOH 122 622 829  HOH HOH A . 
I 2 HOH 123 623 248  HOH HOH A . 
I 2 HOH 124 624 871  HOH HOH A . 
I 2 HOH 125 625 979  HOH HOH A . 
I 2 HOH 126 626 583  HOH HOH A . 
I 2 HOH 127 627 625  HOH HOH A . 
I 2 HOH 128 628 551  HOH HOH A . 
I 2 HOH 129 629 362  HOH HOH A . 
I 2 HOH 130 630 514  HOH HOH A . 
I 2 HOH 131 631 254  HOH HOH A . 
I 2 HOH 132 632 791  HOH HOH A . 
I 2 HOH 133 633 927  HOH HOH A . 
I 2 HOH 134 634 1223 HOH HOH A . 
I 2 HOH 135 635 532  HOH HOH A . 
I 2 HOH 136 636 1306 HOH HOH A . 
I 2 HOH 137 637 189  HOH HOH A . 
I 2 HOH 138 638 1326 HOH HOH A . 
I 2 HOH 139 639 1268 HOH HOH A . 
I 2 HOH 140 640 1374 HOH HOH A . 
I 2 HOH 141 641 991  HOH HOH A . 
I 2 HOH 142 642 706  HOH HOH A . 
I 2 HOH 143 643 547  HOH HOH A . 
I 2 HOH 144 644 482  HOH HOH A . 
I 2 HOH 145 645 354  HOH HOH A . 
I 2 HOH 146 646 636  HOH HOH A . 
I 2 HOH 147 647 400  HOH HOH A . 
I 2 HOH 148 648 1163 HOH HOH A . 
I 2 HOH 149 649 1009 HOH HOH A . 
I 2 HOH 150 650 375  HOH HOH A . 
I 2 HOH 151 651 785  HOH HOH A . 
I 2 HOH 152 652 768  HOH HOH A . 
I 2 HOH 153 653 1087 HOH HOH A . 
I 2 HOH 154 654 1136 HOH HOH A . 
I 2 HOH 155 655 617  HOH HOH A . 
I 2 HOH 156 656 772  HOH HOH A . 
I 2 HOH 157 657 1050 HOH HOH A . 
I 2 HOH 158 658 278  HOH HOH A . 
I 2 HOH 159 659 1436 HOH HOH A . 
I 2 HOH 160 660 685  HOH HOH A . 
I 2 HOH 161 661 776  HOH HOH A . 
I 2 HOH 162 662 1021 HOH HOH A . 
I 2 HOH 163 663 1114 HOH HOH A . 
I 2 HOH 164 664 1112 HOH HOH A . 
I 2 HOH 165 665 591  HOH HOH A . 
I 2 HOH 166 666 1236 HOH HOH A . 
I 2 HOH 167 667 1317 HOH HOH A . 
I 2 HOH 168 668 1454 HOH HOH A . 
I 2 HOH 169 669 1283 HOH HOH A . 
I 2 HOH 170 670 793  HOH HOH A . 
I 2 HOH 171 671 848  HOH HOH A . 
I 2 HOH 172 672 1111 HOH HOH A . 
I 2 HOH 173 673 1382 HOH HOH A . 
I 2 HOH 174 674 1414 HOH HOH A . 
I 2 HOH 175 675 1127 HOH HOH A . 
I 2 HOH 176 676 1328 HOH HOH A . 
I 2 HOH 177 677 1261 HOH HOH A . 
I 2 HOH 178 678 896  HOH HOH A . 
I 2 HOH 179 679 1146 HOH HOH A . 
I 2 HOH 180 680 1277 HOH HOH A . 
I 2 HOH 181 681 1150 HOH HOH A . 
I 2 HOH 182 682 852  HOH HOH A . 
I 2 HOH 183 683 1421 HOH HOH A . 
I 2 HOH 184 684 615  HOH HOH A . 
I 2 HOH 185 685 994  HOH HOH A . 
I 2 HOH 186 686 1310 HOH HOH A . 
I 2 HOH 187 687 1325 HOH HOH A . 
I 2 HOH 188 688 845  HOH HOH A . 
I 2 HOH 189 689 320  HOH HOH A . 
I 2 HOH 190 690 1359 HOH HOH A . 
J 2 HOH 1   501 803  HOH HOH B . 
J 2 HOH 2   502 1097 HOH HOH B . 
J 2 HOH 3   503 122  HOH HOH B . 
J 2 HOH 4   504 1046 HOH HOH B . 
J 2 HOH 5   505 849  HOH HOH B . 
J 2 HOH 6   506 1113 HOH HOH B . 
J 2 HOH 7   507 1376 HOH HOH B . 
J 2 HOH 8   508 799  HOH HOH B . 
J 2 HOH 9   509 670  HOH HOH B . 
J 2 HOH 10  510 964  HOH HOH B . 
J 2 HOH 11  511 530  HOH HOH B . 
J 2 HOH 12  512 851  HOH HOH B . 
J 2 HOH 13  513 932  HOH HOH B . 
J 2 HOH 14  514 1430 HOH HOH B . 
J 2 HOH 15  515 653  HOH HOH B . 
J 2 HOH 16  516 796  HOH HOH B . 
J 2 HOH 17  517 446  HOH HOH B . 
J 2 HOH 18  518 219  HOH HOH B . 
J 2 HOH 19  519 878  HOH HOH B . 
J 2 HOH 20  520 1286 HOH HOH B . 
J 2 HOH 21  521 596  HOH HOH B . 
J 2 HOH 22  522 946  HOH HOH B . 
J 2 HOH 23  523 744  HOH HOH B . 
J 2 HOH 24  524 959  HOH HOH B . 
J 2 HOH 25  525 500  HOH HOH B . 
J 2 HOH 26  526 1387 HOH HOH B . 
J 2 HOH 27  527 45   HOH HOH B . 
J 2 HOH 28  528 886  HOH HOH B . 
J 2 HOH 29  529 955  HOH HOH B . 
J 2 HOH 30  530 268  HOH HOH B . 
J 2 HOH 31  531 259  HOH HOH B . 
J 2 HOH 32  532 17   HOH HOH B . 
J 2 HOH 33  533 1207 HOH HOH B . 
J 2 HOH 34  534 113  HOH HOH B . 
J 2 HOH 35  535 58   HOH HOH B . 
J 2 HOH 36  536 1444 HOH HOH B . 
J 2 HOH 37  537 938  HOH HOH B . 
J 2 HOH 38  538 240  HOH HOH B . 
J 2 HOH 39  539 720  HOH HOH B . 
J 2 HOH 40  540 148  HOH HOH B . 
J 2 HOH 41  541 39   HOH HOH B . 
J 2 HOH 42  542 286  HOH HOH B . 
J 2 HOH 43  543 32   HOH HOH B . 
J 2 HOH 44  544 469  HOH HOH B . 
J 2 HOH 45  545 27   HOH HOH B . 
J 2 HOH 46  546 398  HOH HOH B . 
J 2 HOH 47  547 787  HOH HOH B . 
J 2 HOH 48  548 604  HOH HOH B . 
J 2 HOH 49  549 135  HOH HOH B . 
J 2 HOH 50  550 483  HOH HOH B . 
J 2 HOH 51  551 949  HOH HOH B . 
J 2 HOH 52  552 1017 HOH HOH B . 
J 2 HOH 53  553 290  HOH HOH B . 
J 2 HOH 54  554 119  HOH HOH B . 
J 2 HOH 55  555 186  HOH HOH B . 
J 2 HOH 56  556 684  HOH HOH B . 
J 2 HOH 57  557 217  HOH HOH B . 
J 2 HOH 58  558 1384 HOH HOH B . 
J 2 HOH 59  559 755  HOH HOH B . 
J 2 HOH 60  560 409  HOH HOH B . 
J 2 HOH 61  561 971  HOH HOH B . 
J 2 HOH 62  562 470  HOH HOH B . 
J 2 HOH 63  563 739  HOH HOH B . 
J 2 HOH 64  564 390  HOH HOH B . 
J 2 HOH 65  565 37   HOH HOH B . 
J 2 HOH 66  566 504  HOH HOH B . 
J 2 HOH 67  567 367  HOH HOH B . 
J 2 HOH 68  568 867  HOH HOH B . 
J 2 HOH 69  569 1369 HOH HOH B . 
J 2 HOH 70  570 568  HOH HOH B . 
J 2 HOH 71  571 560  HOH HOH B . 
J 2 HOH 72  572 1391 HOH HOH B . 
J 2 HOH 73  573 576  HOH HOH B . 
J 2 HOH 74  574 1161 HOH HOH B . 
J 2 HOH 75  575 1422 HOH HOH B . 
J 2 HOH 76  576 1234 HOH HOH B . 
J 2 HOH 77  577 962  HOH HOH B . 
J 2 HOH 78  578 173  HOH HOH B . 
J 2 HOH 79  579 590  HOH HOH B . 
J 2 HOH 80  580 1239 HOH HOH B . 
J 2 HOH 81  581 396  HOH HOH B . 
J 2 HOH 82  582 484  HOH HOH B . 
J 2 HOH 83  583 199  HOH HOH B . 
J 2 HOH 84  584 972  HOH HOH B . 
J 2 HOH 85  585 854  HOH HOH B . 
J 2 HOH 86  586 905  HOH HOH B . 
J 2 HOH 87  587 406  HOH HOH B . 
J 2 HOH 88  588 1138 HOH HOH B . 
J 2 HOH 89  589 83   HOH HOH B . 
J 2 HOH 90  590 1048 HOH HOH B . 
J 2 HOH 91  591 417  HOH HOH B . 
J 2 HOH 92  592 510  HOH HOH B . 
J 2 HOH 93  593 1117 HOH HOH B . 
J 2 HOH 94  594 386  HOH HOH B . 
J 2 HOH 95  595 185  HOH HOH B . 
J 2 HOH 96  596 465  HOH HOH B . 
J 2 HOH 97  597 1235 HOH HOH B . 
J 2 HOH 98  598 939  HOH HOH B . 
J 2 HOH 99  599 674  HOH HOH B . 
J 2 HOH 100 600 1175 HOH HOH B . 
J 2 HOH 101 601 968  HOH HOH B . 
J 2 HOH 102 602 589  HOH HOH B . 
J 2 HOH 103 603 104  HOH HOH B . 
J 2 HOH 104 604 1144 HOH HOH B . 
J 2 HOH 105 605 1065 HOH HOH B . 
J 2 HOH 106 606 1159 HOH HOH B . 
J 2 HOH 107 607 815  HOH HOH B . 
J 2 HOH 108 608 1419 HOH HOH B . 
J 2 HOH 109 609 672  HOH HOH B . 
J 2 HOH 110 610 609  HOH HOH B . 
J 2 HOH 111 611 862  HOH HOH B . 
J 2 HOH 112 612 319  HOH HOH B . 
J 2 HOH 113 613 691  HOH HOH B . 
J 2 HOH 114 614 569  HOH HOH B . 
J 2 HOH 115 615 638  HOH HOH B . 
J 2 HOH 116 616 366  HOH HOH B . 
J 2 HOH 117 617 658  HOH HOH B . 
J 2 HOH 118 618 1217 HOH HOH B . 
J 2 HOH 119 619 797  HOH HOH B . 
J 2 HOH 120 620 912  HOH HOH B . 
J 2 HOH 121 621 1049 HOH HOH B . 
J 2 HOH 122 622 710  HOH HOH B . 
J 2 HOH 123 623 221  HOH HOH B . 
J 2 HOH 124 624 93   HOH HOH B . 
J 2 HOH 125 625 427  HOH HOH B . 
J 2 HOH 126 626 1292 HOH HOH B . 
J 2 HOH 127 627 132  HOH HOH B . 
J 2 HOH 128 628 838  HOH HOH B . 
J 2 HOH 129 629 1398 HOH HOH B . 
J 2 HOH 130 630 1198 HOH HOH B . 
J 2 HOH 131 631 1075 HOH HOH B . 
J 2 HOH 132 632 612  HOH HOH B . 
J 2 HOH 133 633 731  HOH HOH B . 
J 2 HOH 134 634 1187 HOH HOH B . 
J 2 HOH 135 635 918  HOH HOH B . 
J 2 HOH 136 636 802  HOH HOH B . 
J 2 HOH 137 637 151  HOH HOH B . 
J 2 HOH 138 638 156  HOH HOH B . 
J 2 HOH 139 639 1123 HOH HOH B . 
J 2 HOH 140 640 1322 HOH HOH B . 
J 2 HOH 141 641 528  HOH HOH B . 
J 2 HOH 142 642 807  HOH HOH B . 
J 2 HOH 143 643 1120 HOH HOH B . 
J 2 HOH 144 644 1301 HOH HOH B . 
J 2 HOH 145 645 95   HOH HOH B . 
J 2 HOH 146 646 743  HOH HOH B . 
J 2 HOH 147 647 1402 HOH HOH B . 
J 2 HOH 148 648 1061 HOH HOH B . 
J 2 HOH 149 649 1390 HOH HOH B . 
J 2 HOH 150 650 1397 HOH HOH B . 
J 2 HOH 151 651 1305 HOH HOH B . 
J 2 HOH 152 652 1253 HOH HOH B . 
J 2 HOH 153 653 1251 HOH HOH B . 
J 2 HOH 154 654 890  HOH HOH B . 
J 2 HOH 155 655 3    HOH HOH B . 
J 2 HOH 156 656 1155 HOH HOH B . 
J 2 HOH 157 657 110  HOH HOH B . 
J 2 HOH 158 658 449  HOH HOH B . 
J 2 HOH 159 659 1349 HOH HOH B . 
J 2 HOH 160 660 116  HOH HOH B . 
J 2 HOH 161 661 1395 HOH HOH B . 
J 2 HOH 162 662 25   HOH HOH B . 
J 2 HOH 163 663 1282 HOH HOH B . 
J 2 HOH 164 664 925  HOH HOH B . 
J 2 HOH 165 665 571  HOH HOH B . 
J 2 HOH 166 666 1298 HOH HOH B . 
J 2 HOH 167 667 207  HOH HOH B . 
K 2 HOH 1   501 565  HOH HOH C . 
K 2 HOH 2   502 1345 HOH HOH C . 
K 2 HOH 3   503 1101 HOH HOH C . 
K 2 HOH 4   504 336  HOH HOH C . 
K 2 HOH 5   505 837  HOH HOH C . 
K 2 HOH 6   506 627  HOH HOH C . 
K 2 HOH 7   507 965  HOH HOH C . 
K 2 HOH 8   508 752  HOH HOH C . 
K 2 HOH 9   509 1152 HOH HOH C . 
K 2 HOH 10  510 652  HOH HOH C . 
K 2 HOH 11  511 1280 HOH HOH C . 
K 2 HOH 12  512 561  HOH HOH C . 
K 2 HOH 13  513 1358 HOH HOH C . 
K 2 HOH 14  514 1066 HOH HOH C . 
K 2 HOH 15  515 503  HOH HOH C . 
K 2 HOH 16  516 646  HOH HOH C . 
K 2 HOH 17  517 899  HOH HOH C . 
K 2 HOH 18  518 66   HOH HOH C . 
K 2 HOH 19  519 1415 HOH HOH C . 
K 2 HOH 20  520 1038 HOH HOH C . 
K 2 HOH 21  521 600  HOH HOH C . 
K 2 HOH 22  522 735  HOH HOH C . 
K 2 HOH 23  523 64   HOH HOH C . 
K 2 HOH 24  524 1039 HOH HOH C . 
K 2 HOH 25  525 1247 HOH HOH C . 
K 2 HOH 26  526 19   HOH HOH C . 
K 2 HOH 27  527 237  HOH HOH C . 
K 2 HOH 28  528 499  HOH HOH C . 
K 2 HOH 29  529 236  HOH HOH C . 
K 2 HOH 30  530 453  HOH HOH C . 
K 2 HOH 31  531 885  HOH HOH C . 
K 2 HOH 32  532 855  HOH HOH C . 
K 2 HOH 33  533 897  HOH HOH C . 
K 2 HOH 34  534 820  HOH HOH C . 
K 2 HOH 35  535 157  HOH HOH C . 
K 2 HOH 36  536 1172 HOH HOH C . 
K 2 HOH 37  537 129  HOH HOH C . 
K 2 HOH 38  538 493  HOH HOH C . 
K 2 HOH 39  539 402  HOH HOH C . 
K 2 HOH 40  540 873  HOH HOH C . 
K 2 HOH 41  541 422  HOH HOH C . 
K 2 HOH 42  542 1393 HOH HOH C . 
K 2 HOH 43  543 1256 HOH HOH C . 
K 2 HOH 44  544 356  HOH HOH C . 
K 2 HOH 45  545 408  HOH HOH C . 
K 2 HOH 46  546 317  HOH HOH C . 
K 2 HOH 47  547 1218 HOH HOH C . 
K 2 HOH 48  548 327  HOH HOH C . 
K 2 HOH 49  549 1347 HOH HOH C . 
K 2 HOH 50  550 73   HOH HOH C . 
K 2 HOH 51  551 1219 HOH HOH C . 
K 2 HOH 52  552 328  HOH HOH C . 
K 2 HOH 53  553 1281 HOH HOH C . 
K 2 HOH 54  554 915  HOH HOH C . 
K 2 HOH 55  555 184  HOH HOH C . 
K 2 HOH 56  556 411  HOH HOH C . 
K 2 HOH 57  557 121  HOH HOH C . 
K 2 HOH 58  558 179  HOH HOH C . 
K 2 HOH 59  559 909  HOH HOH C . 
K 2 HOH 60  560 28   HOH HOH C . 
K 2 HOH 61  561 926  HOH HOH C . 
K 2 HOH 62  562 563  HOH HOH C . 
K 2 HOH 63  563 8    HOH HOH C . 
K 2 HOH 64  564 6    HOH HOH C . 
K 2 HOH 65  565 1205 HOH HOH C . 
K 2 HOH 66  566 200  HOH HOH C . 
K 2 HOH 67  567 634  HOH HOH C . 
K 2 HOH 68  568 729  HOH HOH C . 
K 2 HOH 69  569 112  HOH HOH C . 
K 2 HOH 70  570 850  HOH HOH C . 
K 2 HOH 71  571 270  HOH HOH C . 
K 2 HOH 72  572 614  HOH HOH C . 
K 2 HOH 73  573 718  HOH HOH C . 
K 2 HOH 74  574 80   HOH HOH C . 
K 2 HOH 75  575 498  HOH HOH C . 
K 2 HOH 76  576 626  HOH HOH C . 
K 2 HOH 77  577 676  HOH HOH C . 
K 2 HOH 78  578 222  HOH HOH C . 
K 2 HOH 79  579 87   HOH HOH C . 
K 2 HOH 80  580 1396 HOH HOH C . 
K 2 HOH 81  581 1177 HOH HOH C . 
K 2 HOH 82  582 814  HOH HOH C . 
K 2 HOH 83  583 318  HOH HOH C . 
K 2 HOH 84  584 202  HOH HOH C . 
K 2 HOH 85  585 62   HOH HOH C . 
K 2 HOH 86  586 788  HOH HOH C . 
K 2 HOH 87  587 342  HOH HOH C . 
K 2 HOH 88  588 1399 HOH HOH C . 
K 2 HOH 89  589 144  HOH HOH C . 
K 2 HOH 90  590 105  HOH HOH C . 
K 2 HOH 91  591 1238 HOH HOH C . 
K 2 HOH 92  592 643  HOH HOH C . 
K 2 HOH 93  593 282  HOH HOH C . 
K 2 HOH 94  594 304  HOH HOH C . 
K 2 HOH 95  595 1105 HOH HOH C . 
K 2 HOH 96  596 1202 HOH HOH C . 
K 2 HOH 97  597 856  HOH HOH C . 
K 2 HOH 98  598 1045 HOH HOH C . 
K 2 HOH 99  599 324  HOH HOH C . 
K 2 HOH 100 600 155  HOH HOH C . 
K 2 HOH 101 601 472  HOH HOH C . 
K 2 HOH 102 602 1132 HOH HOH C . 
K 2 HOH 103 603 154  HOH HOH C . 
K 2 HOH 104 604 1233 HOH HOH C . 
K 2 HOH 105 605 795  HOH HOH C . 
K 2 HOH 106 606 515  HOH HOH C . 
K 2 HOH 107 607 491  HOH HOH C . 
K 2 HOH 108 608 1014 HOH HOH C . 
K 2 HOH 109 609 448  HOH HOH C . 
K 2 HOH 110 610 457  HOH HOH C . 
K 2 HOH 111 611 261  HOH HOH C . 
K 2 HOH 112 612 117  HOH HOH C . 
K 2 HOH 113 613 1284 HOH HOH C . 
K 2 HOH 114 614 164  HOH HOH C . 
K 2 HOH 115 615 818  HOH HOH C . 
K 2 HOH 116 616 220  HOH HOH C . 
K 2 HOH 117 617 1051 HOH HOH C . 
K 2 HOH 118 618 1331 HOH HOH C . 
K 2 HOH 119 619 508  HOH HOH C . 
K 2 HOH 120 620 1196 HOH HOH C . 
K 2 HOH 121 621 127  HOH HOH C . 
K 2 HOH 122 622 1174 HOH HOH C . 
K 2 HOH 123 623 263  HOH HOH C . 
K 2 HOH 124 624 1293 HOH HOH C . 
K 2 HOH 125 625 1386 HOH HOH C . 
K 2 HOH 126 626 198  HOH HOH C . 
K 2 HOH 127 627 1407 HOH HOH C . 
K 2 HOH 128 628 919  HOH HOH C . 
K 2 HOH 129 629 1275 HOH HOH C . 
K 2 HOH 130 630 1394 HOH HOH C . 
K 2 HOH 131 631 632  HOH HOH C . 
K 2 HOH 132 632 1195 HOH HOH C . 
K 2 HOH 133 633 1389 HOH HOH C . 
K 2 HOH 134 634 1019 HOH HOH C . 
K 2 HOH 135 635 800  HOH HOH C . 
K 2 HOH 136 636 1264 HOH HOH C . 
K 2 HOH 137 637 1416 HOH HOH C . 
K 2 HOH 138 638 823  HOH HOH C . 
K 2 HOH 139 639 887  HOH HOH C . 
K 2 HOH 140 640 1206 HOH HOH C . 
K 2 HOH 141 641 1122 HOH HOH C . 
K 2 HOH 142 642 1226 HOH HOH C . 
K 2 HOH 143 643 913  HOH HOH C . 
K 2 HOH 144 644 1336 HOH HOH C . 
K 2 HOH 145 645 1294 HOH HOH C . 
K 2 HOH 146 646 770  HOH HOH C . 
K 2 HOH 147 647 1024 HOH HOH C . 
K 2 HOH 148 648 1162 HOH HOH C . 
K 2 HOH 149 649 1197 HOH HOH C . 
K 2 HOH 150 650 1143 HOH HOH C . 
K 2 HOH 151 651 1030 HOH HOH C . 
K 2 HOH 152 652 1020 HOH HOH C . 
K 2 HOH 153 653 1272 HOH HOH C . 
K 2 HOH 154 654 853  HOH HOH C . 
K 2 HOH 155 655 1262 HOH HOH C . 
K 2 HOH 156 656 597  HOH HOH C . 
K 2 HOH 157 657 550  HOH HOH C . 
K 2 HOH 158 658 1192 HOH HOH C . 
K 2 HOH 159 659 1227 HOH HOH C . 
K 2 HOH 160 660 1307 HOH HOH C . 
L 2 HOH 1   501 783  HOH HOH D . 
L 2 HOH 2   502 509  HOH HOH D . 
L 2 HOH 3   503 72   HOH HOH D . 
L 2 HOH 4   504 418  HOH HOH D . 
L 2 HOH 5   505 459  HOH HOH D . 
L 2 HOH 6   506 978  HOH HOH D . 
L 2 HOH 7   507 174  HOH HOH D . 
L 2 HOH 8   508 724  HOH HOH D . 
L 2 HOH 9   509 1029 HOH HOH D . 
L 2 HOH 10  510 193  HOH HOH D . 
L 2 HOH 11  511 1231 HOH HOH D . 
L 2 HOH 12  512 891  HOH HOH D . 
L 2 HOH 13  513 884  HOH HOH D . 
L 2 HOH 14  514 544  HOH HOH D . 
L 2 HOH 15  515 187  HOH HOH D . 
L 2 HOH 16  516 100  HOH HOH D . 
L 2 HOH 17  517 391  HOH HOH D . 
L 2 HOH 18  518 831  HOH HOH D . 
L 2 HOH 19  519 36   HOH HOH D . 
L 2 HOH 20  520 415  HOH HOH D . 
L 2 HOH 21  521 1288 HOH HOH D . 
L 2 HOH 22  522 1224 HOH HOH D . 
L 2 HOH 23  523 1076 HOH HOH D . 
L 2 HOH 24  524 76   HOH HOH D . 
L 2 HOH 25  525 288  HOH HOH D . 
L 2 HOH 26  526 1354 HOH HOH D . 
L 2 HOH 27  527 1333 HOH HOH D . 
L 2 HOH 28  528 358  HOH HOH D . 
L 2 HOH 29  529 98   HOH HOH D . 
L 2 HOH 30  530 1023 HOH HOH D . 
L 2 HOH 31  531 299  HOH HOH D . 
L 2 HOH 32  532 664  HOH HOH D . 
L 2 HOH 33  533 250  HOH HOH D . 
L 2 HOH 34  534 441  HOH HOH D . 
L 2 HOH 35  535 733  HOH HOH D . 
L 2 HOH 36  536 648  HOH HOH D . 
L 2 HOH 37  537 723  HOH HOH D . 
L 2 HOH 38  538 633  HOH HOH D . 
L 2 HOH 39  539 430  HOH HOH D . 
L 2 HOH 40  540 7    HOH HOH D . 
L 2 HOH 41  541 346  HOH HOH D . 
L 2 HOH 42  542 741  HOH HOH D . 
L 2 HOH 43  543 194  HOH HOH D . 
L 2 HOH 44  544 57   HOH HOH D . 
L 2 HOH 45  545 150  HOH HOH D . 
L 2 HOH 46  546 1348 HOH HOH D . 
L 2 HOH 47  547 158  HOH HOH D . 
L 2 HOH 48  548 584  HOH HOH D . 
L 2 HOH 49  549 542  HOH HOH D . 
L 2 HOH 50  550 229  HOH HOH D . 
L 2 HOH 51  551 233  HOH HOH D . 
L 2 HOH 52  552 392  HOH HOH D . 
L 2 HOH 53  553 276  HOH HOH D . 
L 2 HOH 54  554 792  HOH HOH D . 
L 2 HOH 55  555 1363 HOH HOH D . 
L 2 HOH 56  556 987  HOH HOH D . 
L 2 HOH 57  557 673  HOH HOH D . 
L 2 HOH 58  558 279  HOH HOH D . 
L 2 HOH 59  559 48   HOH HOH D . 
L 2 HOH 60  560 108  HOH HOH D . 
L 2 HOH 61  561 322  HOH HOH D . 
L 2 HOH 62  562 305  HOH HOH D . 
L 2 HOH 63  563 732  HOH HOH D . 
L 2 HOH 64  564 1368 HOH HOH D . 
L 2 HOH 65  565 1098 HOH HOH D . 
L 2 HOH 66  566 1028 HOH HOH D . 
L 2 HOH 67  567 688  HOH HOH D . 
L 2 HOH 68  568 1450 HOH HOH D . 
L 2 HOH 69  569 355  HOH HOH D . 
L 2 HOH 70  570 109  HOH HOH D . 
L 2 HOH 71  571 74   HOH HOH D . 
L 2 HOH 72  572 338  HOH HOH D . 
L 2 HOH 73  573 874  HOH HOH D . 
L 2 HOH 74  574 123  HOH HOH D . 
L 2 HOH 75  575 1302 HOH HOH D . 
L 2 HOH 76  576 977  HOH HOH D . 
L 2 HOH 77  577 1026 HOH HOH D . 
L 2 HOH 78  578 439  HOH HOH D . 
L 2 HOH 79  579 754  HOH HOH D . 
L 2 HOH 80  580 344  HOH HOH D . 
L 2 HOH 81  581 1339 HOH HOH D . 
L 2 HOH 82  582 256  HOH HOH D . 
L 2 HOH 83  583 381  HOH HOH D . 
L 2 HOH 84  584 432  HOH HOH D . 
L 2 HOH 85  585 134  HOH HOH D . 
L 2 HOH 86  586 911  HOH HOH D . 
L 2 HOH 87  587 1158 HOH HOH D . 
L 2 HOH 88  588 827  HOH HOH D . 
L 2 HOH 89  589 167  HOH HOH D . 
L 2 HOH 90  590 892  HOH HOH D . 
L 2 HOH 91  591 742  HOH HOH D . 
L 2 HOH 92  592 241  HOH HOH D . 
L 2 HOH 93  593 1403 HOH HOH D . 
L 2 HOH 94  594 190  HOH HOH D . 
L 2 HOH 95  595 1229 HOH HOH D . 
L 2 HOH 96  596 330  HOH HOH D . 
L 2 HOH 97  597 206  HOH HOH D . 
L 2 HOH 98  598 1013 HOH HOH D . 
L 2 HOH 99  599 1228 HOH HOH D . 
L 2 HOH 100 600 1058 HOH HOH D . 
L 2 HOH 101 601 545  HOH HOH D . 
L 2 HOH 102 602 769  HOH HOH D . 
L 2 HOH 103 603 1199 HOH HOH D . 
L 2 HOH 104 604 645  HOH HOH D . 
L 2 HOH 105 605 495  HOH HOH D . 
L 2 HOH 106 606 570  HOH HOH D . 
L 2 HOH 107 607 522  HOH HOH D . 
L 2 HOH 108 608 1022 HOH HOH D . 
L 2 HOH 109 609 1246 HOH HOH D . 
L 2 HOH 110 610 464  HOH HOH D . 
L 2 HOH 111 611 102  HOH HOH D . 
L 2 HOH 112 612 280  HOH HOH D . 
L 2 HOH 113 613 300  HOH HOH D . 
L 2 HOH 114 614 85   HOH HOH D . 
L 2 HOH 115 615 382  HOH HOH D . 
L 2 HOH 116 616 1004 HOH HOH D . 
L 2 HOH 117 617 952  HOH HOH D . 
L 2 HOH 118 618 640  HOH HOH D . 
L 2 HOH 119 619 1036 HOH HOH D . 
L 2 HOH 120 620 1165 HOH HOH D . 
L 2 HOH 121 621 683  HOH HOH D . 
L 2 HOH 122 622 746  HOH HOH D . 
L 2 HOH 123 623 486  HOH HOH D . 
L 2 HOH 124 624 523  HOH HOH D . 
L 2 HOH 125 625 786  HOH HOH D . 
L 2 HOH 126 626 1060 HOH HOH D . 
L 2 HOH 127 627 700  HOH HOH D . 
L 2 HOH 128 628 1100 HOH HOH D . 
L 2 HOH 129 629 607  HOH HOH D . 
L 2 HOH 130 630 377  HOH HOH D . 
L 2 HOH 131 631 1291 HOH HOH D . 
L 2 HOH 132 632 1448 HOH HOH D . 
L 2 HOH 133 633 1193 HOH HOH D . 
L 2 HOH 134 634 474  HOH HOH D . 
L 2 HOH 135 635 1338 HOH HOH D . 
L 2 HOH 136 636 1116 HOH HOH D . 
L 2 HOH 137 637 1034 HOH HOH D . 
L 2 HOH 138 638 1185 HOH HOH D . 
L 2 HOH 139 639 435  HOH HOH D . 
L 2 HOH 140 640 937  HOH HOH D . 
L 2 HOH 141 641 687  HOH HOH D . 
L 2 HOH 142 642 1090 HOH HOH D . 
L 2 HOH 143 643 984  HOH HOH D . 
L 2 HOH 144 644 1230 HOH HOH D . 
L 2 HOH 145 645 1080 HOH HOH D . 
L 2 HOH 146 646 1327 HOH HOH D . 
L 2 HOH 147 647 804  HOH HOH D . 
L 2 HOH 148 648 1042 HOH HOH D . 
L 2 HOH 149 649 1269 HOH HOH D . 
L 2 HOH 150 650 940  HOH HOH D . 
L 2 HOH 151 651 921  HOH HOH D . 
L 2 HOH 152 652 1169 HOH HOH D . 
L 2 HOH 153 653 1330 HOH HOH D . 
L 2 HOH 154 654 1168 HOH HOH D . 
L 2 HOH 155 655 1357 HOH HOH D . 
L 2 HOH 156 656 1027 HOH HOH D . 
L 2 HOH 157 657 1296 HOH HOH D . 
L 2 HOH 158 658 956  HOH HOH D . 
L 2 HOH 159 659 970  HOH HOH D . 
M 2 HOH 1   501 844  HOH HOH E . 
M 2 HOH 2   502 1088 HOH HOH E . 
M 2 HOH 3   503 1139 HOH HOH E . 
M 2 HOH 4   504 1151 HOH HOH E . 
M 2 HOH 5   505 1082 HOH HOH E . 
M 2 HOH 6   506 809  HOH HOH E . 
M 2 HOH 7   507 1213 HOH HOH E . 
M 2 HOH 8   508 1329 HOH HOH E . 
M 2 HOH 9   509 941  HOH HOH E . 
M 2 HOH 10  510 1340 HOH HOH E . 
M 2 HOH 11  511 816  HOH HOH E . 
M 2 HOH 12  512 1377 HOH HOH E . 
M 2 HOH 13  513 875  HOH HOH E . 
M 2 HOH 14  514 1119 HOH HOH E . 
M 2 HOH 15  515 1160 HOH HOH E . 
M 2 HOH 16  516 1266 HOH HOH E . 
M 2 HOH 17  517 525  HOH HOH E . 
M 2 HOH 18  518 944  HOH HOH E . 
M 2 HOH 19  519 697  HOH HOH E . 
M 2 HOH 20  520 50   HOH HOH E . 
M 2 HOH 21  521 111  HOH HOH E . 
M 2 HOH 22  522 1140 HOH HOH E . 
M 2 HOH 23  523 1439 HOH HOH E . 
M 2 HOH 24  524 681  HOH HOH E . 
M 2 HOH 25  525 1425 HOH HOH E . 
M 2 HOH 26  526 647  HOH HOH E . 
M 2 HOH 27  527 649  HOH HOH E . 
M 2 HOH 28  528 131  HOH HOH E . 
M 2 HOH 29  529 747  HOH HOH E . 
M 2 HOH 30  530 1210 HOH HOH E . 
M 2 HOH 31  531 1209 HOH HOH E . 
M 2 HOH 32  532 1426 HOH HOH E . 
M 2 HOH 33  533 182  HOH HOH E . 
M 2 HOH 34  534 644  HOH HOH E . 
M 2 HOH 35  535 178  HOH HOH E . 
M 2 HOH 36  536 960  HOH HOH E . 
M 2 HOH 37  537 771  HOH HOH E . 
M 2 HOH 38  538 559  HOH HOH E . 
M 2 HOH 39  539 494  HOH HOH E . 
M 2 HOH 40  540 79   HOH HOH E . 
M 2 HOH 41  541 624  HOH HOH E . 
M 2 HOH 42  542 43   HOH HOH E . 
M 2 HOH 43  543 501  HOH HOH E . 
M 2 HOH 44  544 176  HOH HOH E . 
M 2 HOH 45  545 1265 HOH HOH E . 
M 2 HOH 46  546 138  HOH HOH E . 
M 2 HOH 47  547 989  HOH HOH E . 
M 2 HOH 48  548 114  HOH HOH E . 
M 2 HOH 49  549 950  HOH HOH E . 
M 2 HOH 50  550 234  HOH HOH E . 
M 2 HOH 51  551 251  HOH HOH E . 
M 2 HOH 52  552 903  HOH HOH E . 
M 2 HOH 53  553 15   HOH HOH E . 
M 2 HOH 54  554 1441 HOH HOH E . 
M 2 HOH 55  555 323  HOH HOH E . 
M 2 HOH 56  556 260  HOH HOH E . 
M 2 HOH 57  557 898  HOH HOH E . 
M 2 HOH 58  558 957  HOH HOH E . 
M 2 HOH 59  559 660  HOH HOH E . 
M 2 HOH 60  560 410  HOH HOH E . 
M 2 HOH 61  561 438  HOH HOH E . 
M 2 HOH 62  562 298  HOH HOH E . 
M 2 HOH 63  563 341  HOH HOH E . 
M 2 HOH 64  564 487  HOH HOH E . 
M 2 HOH 65  565 405  HOH HOH E . 
M 2 HOH 66  566 953  HOH HOH E . 
M 2 HOH 67  567 1006 HOH HOH E . 
M 2 HOH 68  568 1304 HOH HOH E . 
M 2 HOH 69  569 51   HOH HOH E . 
M 2 HOH 70  570 996  HOH HOH E . 
M 2 HOH 71  571 5    HOH HOH E . 
M 2 HOH 72  572 162  HOH HOH E . 
M 2 HOH 73  573 833  HOH HOH E . 
M 2 HOH 74  574 502  HOH HOH E . 
M 2 HOH 75  575 492  HOH HOH E . 
M 2 HOH 76  576 592  HOH HOH E . 
M 2 HOH 77  577 580  HOH HOH E . 
M 2 HOH 78  578 265  HOH HOH E . 
M 2 HOH 79  579 1375 HOH HOH E . 
M 2 HOH 80  580 982  HOH HOH E . 
M 2 HOH 81  581 455  HOH HOH E . 
M 2 HOH 82  582 136  HOH HOH E . 
M 2 HOH 83  583 471  HOH HOH E . 
M 2 HOH 84  584 1318 HOH HOH E . 
M 2 HOH 85  585 598  HOH HOH E . 
M 2 HOH 86  586 1410 HOH HOH E . 
M 2 HOH 87  587 169  HOH HOH E . 
M 2 HOH 88  588 990  HOH HOH E . 
M 2 HOH 89  589 1204 HOH HOH E . 
M 2 HOH 90  590 321  HOH HOH E . 
M 2 HOH 91  591 468  HOH HOH E . 
M 2 HOH 92  592 146  HOH HOH E . 
M 2 HOH 93  593 655  HOH HOH E . 
M 2 HOH 94  594 780  HOH HOH E . 
M 2 HOH 95  595 1186 HOH HOH E . 
M 2 HOH 96  596 142  HOH HOH E . 
M 2 HOH 97  597 1216 HOH HOH E . 
M 2 HOH 98  598 273  HOH HOH E . 
M 2 HOH 99  599 67   HOH HOH E . 
M 2 HOH 100 600 975  HOH HOH E . 
M 2 HOH 101 601 232  HOH HOH E . 
M 2 HOH 102 602 372  HOH HOH E . 
M 2 HOH 103 603 223  HOH HOH E . 
M 2 HOH 104 604 293  HOH HOH E . 
M 2 HOH 105 605 384  HOH HOH E . 
M 2 HOH 106 606 168  HOH HOH E . 
M 2 HOH 107 607 13   HOH HOH E . 
M 2 HOH 108 608 264  HOH HOH E . 
M 2 HOH 109 609 4    HOH HOH E . 
M 2 HOH 110 610 302  HOH HOH E . 
M 2 HOH 111 611 183  HOH HOH E . 
M 2 HOH 112 612 266  HOH HOH E . 
M 2 HOH 113 613 923  HOH HOH E . 
M 2 HOH 114 614 1011 HOH HOH E . 
M 2 HOH 115 615 518  HOH HOH E . 
M 2 HOH 116 616 601  HOH HOH E . 
M 2 HOH 117 617 922  HOH HOH E . 
M 2 HOH 118 618 651  HOH HOH E . 
M 2 HOH 119 619 228  HOH HOH E . 
M 2 HOH 120 620 1411 HOH HOH E . 
M 2 HOH 121 621 1383 HOH HOH E . 
M 2 HOH 122 622 1418 HOH HOH E . 
M 2 HOH 123 623 209  HOH HOH E . 
M 2 HOH 124 624 1147 HOH HOH E . 
M 2 HOH 125 625 1279 HOH HOH E . 
M 2 HOH 126 626 736  HOH HOH E . 
M 2 HOH 127 627 436  HOH HOH E . 
M 2 HOH 128 628 373  HOH HOH E . 
M 2 HOH 129 629 368  HOH HOH E . 
M 2 HOH 130 630 539  HOH HOH E . 
M 2 HOH 131 631 656  HOH HOH E . 
M 2 HOH 132 632 517  HOH HOH E . 
M 2 HOH 133 633 357  HOH HOH E . 
M 2 HOH 134 634 610  HOH HOH E . 
M 2 HOH 135 635 1135 HOH HOH E . 
M 2 HOH 136 636 443  HOH HOH E . 
M 2 HOH 137 637 696  HOH HOH E . 
M 2 HOH 138 638 817  HOH HOH E . 
M 2 HOH 139 639 143  HOH HOH E . 
M 2 HOH 140 640 175  HOH HOH E . 
M 2 HOH 141 641 863  HOH HOH E . 
M 2 HOH 142 642 1086 HOH HOH E . 
M 2 HOH 143 643 1179 HOH HOH E . 
M 2 HOH 144 644 130  HOH HOH E . 
M 2 HOH 145 645 824  HOH HOH E . 
M 2 HOH 146 646 689  HOH HOH E . 
M 2 HOH 147 647 548  HOH HOH E . 
M 2 HOH 148 648 421  HOH HOH E . 
M 2 HOH 149 649 1018 HOH HOH E . 
M 2 HOH 150 650 928  HOH HOH E . 
M 2 HOH 151 651 760  HOH HOH E . 
M 2 HOH 152 652 1367 HOH HOH E . 
M 2 HOH 153 653 1189 HOH HOH E . 
M 2 HOH 154 654 1300 HOH HOH E . 
M 2 HOH 155 655 945  HOH HOH E . 
M 2 HOH 156 656 1273 HOH HOH E . 
M 2 HOH 157 657 1337 HOH HOH E . 
M 2 HOH 158 658 1344 HOH HOH E . 
M 2 HOH 159 659 352  HOH HOH E . 
M 2 HOH 160 660 128  HOH HOH E . 
M 2 HOH 161 661 1334 HOH HOH E . 
M 2 HOH 162 662 1221 HOH HOH E . 
M 2 HOH 163 663 1447 HOH HOH E . 
M 2 HOH 164 664 842  HOH HOH E . 
M 2 HOH 165 665 1089 HOH HOH E . 
M 2 HOH 166 666 1406 HOH HOH E . 
M 2 HOH 167 667 497  HOH HOH E . 
M 2 HOH 168 668 969  HOH HOH E . 
M 2 HOH 169 669 1137 HOH HOH E . 
M 2 HOH 170 670 866  HOH HOH E . 
M 2 HOH 171 671 1362 HOH HOH E . 
M 2 HOH 172 672 986  HOH HOH E . 
M 2 HOH 173 673 1041 HOH HOH E . 
M 2 HOH 174 674 1248 HOH HOH E . 
M 2 HOH 175 675 858  HOH HOH E . 
M 2 HOH 176 676 819  HOH HOH E . 
M 2 HOH 177 677 1353 HOH HOH E . 
M 2 HOH 178 678 1451 HOH HOH E . 
M 2 HOH 179 679 1408 HOH HOH E . 
M 2 HOH 180 680 567  HOH HOH E . 
M 2 HOH 181 681 581  HOH HOH E . 
M 2 HOH 182 682 212  HOH HOH E . 
M 2 HOH 183 683 766  HOH HOH E . 
M 2 HOH 184 684 1379 HOH HOH E . 
M 2 HOH 185 685 1031 HOH HOH E . 
M 2 HOH 186 686 1404 HOH HOH E . 
M 2 HOH 187 687 1092 HOH HOH E . 
M 2 HOH 188 688 1102 HOH HOH E . 
M 2 HOH 189 689 1263 HOH HOH E . 
M 2 HOH 190 690 1405 HOH HOH E . 
M 2 HOH 191 691 1106 HOH HOH E . 
M 2 HOH 192 692 1035 HOH HOH E . 
M 2 HOH 193 693 1190 HOH HOH E . 
M 2 HOH 194 694 665  HOH HOH E . 
M 2 HOH 195 695 340  HOH HOH E . 
M 2 HOH 196 696 657  HOH HOH E . 
M 2 HOH 197 697 1270 HOH HOH E . 
M 2 HOH 198 698 425  HOH HOH E . 
M 2 HOH 199 699 698  HOH HOH E . 
M 2 HOH 200 700 1361 HOH HOH E . 
N 2 HOH 1   501 442  HOH HOH F . 
N 2 HOH 2   502 1068 HOH HOH F . 
N 2 HOH 3   503 825  HOH HOH F . 
N 2 HOH 4   504 1400 HOH HOH F . 
N 2 HOH 5   505 1319 HOH HOH F . 
N 2 HOH 6   506 1125 HOH HOH F . 
N 2 HOH 7   507 553  HOH HOH F . 
N 2 HOH 8   508 434  HOH HOH F . 
N 2 HOH 9   509 257  HOH HOH F . 
N 2 HOH 10  510 1191 HOH HOH F . 
N 2 HOH 11  511 588  HOH HOH F . 
N 2 HOH 12  512 1084 HOH HOH F . 
N 2 HOH 13  513 291  HOH HOH F . 
N 2 HOH 14  514 520  HOH HOH F . 
N 2 HOH 15  515 1083 HOH HOH F . 
N 2 HOH 16  516 1303 HOH HOH F . 
N 2 HOH 17  517 1081 HOH HOH F . 
N 2 HOH 18  518 603  HOH HOH F . 
N 2 HOH 19  519 715  HOH HOH F . 
N 2 HOH 20  520 1335 HOH HOH F . 
N 2 HOH 21  521 437  HOH HOH F . 
N 2 HOH 22  522 239  HOH HOH F . 
N 2 HOH 23  523 554  HOH HOH F . 
N 2 HOH 24  524 566  HOH HOH F . 
N 2 HOH 25  525 976  HOH HOH F . 
N 2 HOH 26  526 602  HOH HOH F . 
N 2 HOH 27  527 271  HOH HOH F . 
N 2 HOH 28  528 661  HOH HOH F . 
N 2 HOH 29  529 456  HOH HOH F . 
N 2 HOH 30  530 30   HOH HOH F . 
N 2 HOH 31  531 91   HOH HOH F . 
N 2 HOH 32  532 10   HOH HOH F . 
N 2 HOH 33  533 904  HOH HOH F . 
N 2 HOH 34  534 388  HOH HOH F . 
N 2 HOH 35  535 2    HOH HOH F . 
N 2 HOH 36  536 452  HOH HOH F . 
N 2 HOH 37  537 728  HOH HOH F . 
N 2 HOH 38  538 1    HOH HOH F . 
N 2 HOH 39  539 297  HOH HOH F . 
N 2 HOH 40  540 65   HOH HOH F . 
N 2 HOH 41  541 1002 HOH HOH F . 
N 2 HOH 42  542 120  HOH HOH F . 
N 2 HOH 43  543 1250 HOH HOH F . 
N 2 HOH 44  544 538  HOH HOH F . 
N 2 HOH 45  545 536  HOH HOH F . 
N 2 HOH 46  546 216  HOH HOH F . 
N 2 HOH 47  547 312  HOH HOH F . 
N 2 HOH 48  548 1428 HOH HOH F . 
N 2 HOH 49  549 675  HOH HOH F . 
N 2 HOH 50  550 572  HOH HOH F . 
N 2 HOH 51  551 1380 HOH HOH F . 
N 2 HOH 52  552 303  HOH HOH F . 
N 2 HOH 53  553 679  HOH HOH F . 
N 2 HOH 54  554 535  HOH HOH F . 
N 2 HOH 55  555 249  HOH HOH F . 
N 2 HOH 56  556 71   HOH HOH F . 
N 2 HOH 57  557 1091 HOH HOH F . 
N 2 HOH 58  558 1342 HOH HOH F . 
N 2 HOH 59  559 379  HOH HOH F . 
N 2 HOH 60  560 9    HOH HOH F . 
N 2 HOH 61  561 620  HOH HOH F . 
N 2 HOH 62  562 865  HOH HOH F . 
N 2 HOH 63  563 1285 HOH HOH F . 
N 2 HOH 64  564 642  HOH HOH F . 
N 2 HOH 65  565 99   HOH HOH F . 
N 2 HOH 66  566 1003 HOH HOH F . 
N 2 HOH 67  567 1323 HOH HOH F . 
N 2 HOH 68  568 1208 HOH HOH F . 
N 2 HOH 69  569 38   HOH HOH F . 
N 2 HOH 70  570 360  HOH HOH F . 
N 2 HOH 71  571 420  HOH HOH F . 
N 2 HOH 72  572 255  HOH HOH F . 
N 2 HOH 73  573 993  HOH HOH F . 
N 2 HOH 74  574 163  HOH HOH F . 
N 2 HOH 75  575 371  HOH HOH F . 
N 2 HOH 76  576 349  HOH HOH F . 
N 2 HOH 77  577 895  HOH HOH F . 
N 2 HOH 78  578 335  HOH HOH F . 
N 2 HOH 79  579 191  HOH HOH F . 
N 2 HOH 80  580 541  HOH HOH F . 
N 2 HOH 81  581 920  HOH HOH F . 
N 2 HOH 82  582 734  HOH HOH F . 
N 2 HOH 83  583 533  HOH HOH F . 
N 2 HOH 84  584 1015 HOH HOH F . 
N 2 HOH 85  585 1096 HOH HOH F . 
N 2 HOH 86  586 149  HOH HOH F . 
N 2 HOH 87  587 394  HOH HOH F . 
N 2 HOH 88  588 147  HOH HOH F . 
N 2 HOH 89  589 188  HOH HOH F . 
N 2 HOH 90  590 1000 HOH HOH F . 
N 2 HOH 91  591 475  HOH HOH F . 
N 2 HOH 92  592 637  HOH HOH F . 
N 2 HOH 93  593 393  HOH HOH F . 
N 2 HOH 94  594 830  HOH HOH F . 
N 2 HOH 95  595 253  HOH HOH F . 
N 2 HOH 96  596 215  HOH HOH F . 
N 2 HOH 97  597 629  HOH HOH F . 
N 2 HOH 98  598 428  HOH HOH F . 
N 2 HOH 99  599 737  HOH HOH F . 
N 2 HOH 100 600 145  HOH HOH F . 
N 2 HOH 101 601 292  HOH HOH F . 
N 2 HOH 102 602 461  HOH HOH F . 
N 2 HOH 103 603 82   HOH HOH F . 
N 2 HOH 104 604 42   HOH HOH F . 
N 2 HOH 105 605 714  HOH HOH F . 
N 2 HOH 106 606 613  HOH HOH F . 
N 2 HOH 107 607 1085 HOH HOH F . 
N 2 HOH 108 608 22   HOH HOH F . 
N 2 HOH 109 609 395  HOH HOH F . 
N 2 HOH 110 610 103  HOH HOH F . 
N 2 HOH 111 611 573  HOH HOH F . 
N 2 HOH 112 612 333  HOH HOH F . 
N 2 HOH 113 613 519  HOH HOH F . 
N 2 HOH 114 614 556  HOH HOH F . 
N 2 HOH 115 615 246  HOH HOH F . 
N 2 HOH 116 616 369  HOH HOH F . 
N 2 HOH 117 617 712  HOH HOH F . 
N 2 HOH 118 618 70   HOH HOH F . 
N 2 HOH 119 619 195  HOH HOH F . 
N 2 HOH 120 620 967  HOH HOH F . 
N 2 HOH 121 621 936  HOH HOH F . 
N 2 HOH 122 622 1214 HOH HOH F . 
N 2 HOH 123 623 716  HOH HOH F . 
N 2 HOH 124 624 450  HOH HOH F . 
N 2 HOH 125 625 1141 HOH HOH F . 
N 2 HOH 126 626 258  HOH HOH F . 
N 2 HOH 127 627 115  HOH HOH F . 
N 2 HOH 128 628 782  HOH HOH F . 
N 2 HOH 129 629 359  HOH HOH F . 
N 2 HOH 130 630 954  HOH HOH F . 
N 2 HOH 131 631 832  HOH HOH F . 
N 2 HOH 132 632 21   HOH HOH F . 
N 2 HOH 133 633 671  HOH HOH F . 
N 2 HOH 134 634 686  HOH HOH F . 
N 2 HOH 135 635 721  HOH HOH F . 
N 2 HOH 136 636 1095 HOH HOH F . 
N 2 HOH 137 637 951  HOH HOH F . 
N 2 HOH 138 638 1241 HOH HOH F . 
N 2 HOH 139 639 197  HOH HOH F . 
N 2 HOH 140 640 1057 HOH HOH F . 
N 2 HOH 141 641 1258 HOH HOH F . 
N 2 HOH 142 642 711  HOH HOH F . 
N 2 HOH 143 643 314  HOH HOH F . 
N 2 HOH 144 644 496  HOH HOH F . 
N 2 HOH 145 645 1110 HOH HOH F . 
N 2 HOH 146 646 558  HOH HOH F . 
N 2 HOH 147 647 1370 HOH HOH F . 
N 2 HOH 148 648 1356 HOH HOH F . 
N 2 HOH 149 649 1378 HOH HOH F . 
N 2 HOH 150 650 1043 HOH HOH F . 
N 2 HOH 151 651 1312 HOH HOH F . 
N 2 HOH 152 652 826  HOH HOH F . 
N 2 HOH 153 653 1215 HOH HOH F . 
N 2 HOH 154 654 1372 HOH HOH F . 
N 2 HOH 155 655 980  HOH HOH F . 
N 2 HOH 156 656 1025 HOH HOH F . 
N 2 HOH 157 657 798  HOH HOH F . 
N 2 HOH 158 658 1180 HOH HOH F . 
N 2 HOH 159 659 1115 HOH HOH F . 
N 2 HOH 160 660 365  HOH HOH F . 
N 2 HOH 161 661 1194 HOH HOH F . 
N 2 HOH 162 662 203  HOH HOH F . 
N 2 HOH 163 663 1295 HOH HOH F . 
N 2 HOH 164 664 828  HOH HOH F . 
N 2 HOH 165 665 1166 HOH HOH F . 
N 2 HOH 166 666 1183 HOH HOH F . 
N 2 HOH 167 667 727  HOH HOH F . 
N 2 HOH 168 668 1053 HOH HOH F . 
N 2 HOH 169 669 370  HOH HOH F . 
N 2 HOH 170 670 1437 HOH HOH F . 
N 2 HOH 171 671 1001 HOH HOH F . 
N 2 HOH 172 672 893  HOH HOH F . 
N 2 HOH 173 673 1130 HOH HOH F . 
N 2 HOH 174 674 966  HOH HOH F . 
N 2 HOH 175 675 1099 HOH HOH F . 
N 2 HOH 176 676 348  HOH HOH F . 
N 2 HOH 177 677 1309 HOH HOH F . 
N 2 HOH 178 678 1184 HOH HOH F . 
N 2 HOH 179 679 546  HOH HOH F . 
N 2 HOH 180 680 1257 HOH HOH F . 
N 2 HOH 181 681 18   HOH HOH F . 
N 2 HOH 182 682 692  HOH HOH F . 
N 2 HOH 183 683 1360 HOH HOH F . 
N 2 HOH 184 684 1308 HOH HOH F . 
N 2 HOH 185 685 160  HOH HOH F . 
N 2 HOH 186 686 1427 HOH HOH F . 
N 2 HOH 187 687 1077 HOH HOH F . 
N 2 HOH 188 688 1385 HOH HOH F . 
N 2 HOH 189 689 740  HOH HOH F . 
N 2 HOH 190 690 1145 HOH HOH F . 
O 2 HOH 1   501 781  HOH HOH G . 
O 2 HOH 2   502 680  HOH HOH G . 
O 2 HOH 3   503 1453 HOH HOH G . 
O 2 HOH 4   504 981  HOH HOH G . 
O 2 HOH 5   505 296  HOH HOH G . 
O 2 HOH 6   506 726  HOH HOH G . 
O 2 HOH 7   507 431  HOH HOH G . 
O 2 HOH 8   508 1455 HOH HOH G . 
O 2 HOH 9   509 841  HOH HOH G . 
O 2 HOH 10  510 244  HOH HOH G . 
O 2 HOH 11  511 1133 HOH HOH G . 
O 2 HOH 12  512 947  HOH HOH G . 
O 2 HOH 13  513 313  HOH HOH G . 
O 2 HOH 14  514 41   HOH HOH G . 
O 2 HOH 15  515 1452 HOH HOH G . 
O 2 HOH 16  516 1094 HOH HOH G . 
O 2 HOH 17  517 759  HOH HOH G . 
O 2 HOH 18  518 33   HOH HOH G . 
O 2 HOH 19  519 1423 HOH HOH G . 
O 2 HOH 20  520 506  HOH HOH G . 
O 2 HOH 21  521 1118 HOH HOH G . 
O 2 HOH 22  522 881  HOH HOH G . 
O 2 HOH 23  523 277  HOH HOH G . 
O 2 HOH 24  524 88   HOH HOH G . 
O 2 HOH 25  525 466  HOH HOH G . 
O 2 HOH 26  526 165  HOH HOH G . 
O 2 HOH 27  527 78   HOH HOH G . 
O 2 HOH 28  528 235  HOH HOH G . 
O 2 HOH 29  529 485  HOH HOH G . 
O 2 HOH 30  530 462  HOH HOH G . 
O 2 HOH 31  531 106  HOH HOH G . 
O 2 HOH 32  532 345  HOH HOH G . 
O 2 HOH 33  533 337  HOH HOH G . 
O 2 HOH 34  534 526  HOH HOH G . 
O 2 HOH 35  535 44   HOH HOH G . 
O 2 HOH 36  536 75   HOH HOH G . 
O 2 HOH 37  537 332  HOH HOH G . 
O 2 HOH 38  538 595  HOH HOH G . 
O 2 HOH 39  539 654  HOH HOH G . 
O 2 HOH 40  540 161  HOH HOH G . 
O 2 HOH 41  541 92   HOH HOH G . 
O 2 HOH 42  542 107  HOH HOH G . 
O 2 HOH 43  543 440  HOH HOH G . 
O 2 HOH 44  544 1341 HOH HOH G . 
O 2 HOH 45  545 46   HOH HOH G . 
O 2 HOH 46  546 621  HOH HOH G . 
O 2 HOH 47  547 722  HOH HOH G . 
O 2 HOH 48  548 635  HOH HOH G . 
O 2 HOH 49  549 68   HOH HOH G . 
O 2 HOH 50  550 23   HOH HOH G . 
O 2 HOH 51  551 20   HOH HOH G . 
O 2 HOH 52  552 702  HOH HOH G . 
O 2 HOH 53  553 935  HOH HOH G . 
O 2 HOH 54  554 562  HOH HOH G . 
O 2 HOH 55  555 1203 HOH HOH G . 
O 2 HOH 56  556 227  HOH HOH G . 
O 2 HOH 57  557 364  HOH HOH G . 
O 2 HOH 58  558 1037 HOH HOH G . 
O 2 HOH 59  559 934  HOH HOH G . 
O 2 HOH 60  560 611  HOH HOH G . 
O 2 HOH 61  561 564  HOH HOH G . 
O 2 HOH 62  562 480  HOH HOH G . 
O 2 HOH 63  563 552  HOH HOH G . 
O 2 HOH 64  564 1121 HOH HOH G . 
O 2 HOH 65  565 53   HOH HOH G . 
O 2 HOH 66  566 606  HOH HOH G . 
O 2 HOH 67  567 630  HOH HOH G . 
O 2 HOH 68  568 1156 HOH HOH G . 
O 2 HOH 69  569 894  HOH HOH G . 
O 2 HOH 70  570 479  HOH HOH G . 
O 2 HOH 71  571 974  HOH HOH G . 
O 2 HOH 72  572 1128 HOH HOH G . 
O 2 HOH 73  573 1243 HOH HOH G . 
O 2 HOH 74  574 56   HOH HOH G . 
O 2 HOH 75  575 1409 HOH HOH G . 
O 2 HOH 76  576 433  HOH HOH G . 
O 2 HOH 77  577 285  HOH HOH G . 
O 2 HOH 78  578 775  HOH HOH G . 
O 2 HOH 79  579 489  HOH HOH G . 
O 2 HOH 80  580 882  HOH HOH G . 
O 2 HOH 81  581 404  HOH HOH G . 
O 2 HOH 82  582 243  HOH HOH G . 
O 2 HOH 83  583 35   HOH HOH G . 
O 2 HOH 84  584 834  HOH HOH G . 
O 2 HOH 85  585 1067 HOH HOH G . 
O 2 HOH 86  586 1167 HOH HOH G . 
O 2 HOH 87  587 311  HOH HOH G . 
O 2 HOH 88  588 1074 HOH HOH G . 
O 2 HOH 89  589 1056 HOH HOH G . 
O 2 HOH 90  590 511  HOH HOH G . 
O 2 HOH 91  591 177  HOH HOH G . 
O 2 HOH 92  592 329  HOH HOH G . 
O 2 HOH 93  593 1073 HOH HOH G . 
O 2 HOH 94  594 512  HOH HOH G . 
O 2 HOH 95  595 924  HOH HOH G . 
O 2 HOH 96  596 126  HOH HOH G . 
O 2 HOH 97  597 380  HOH HOH G . 
O 2 HOH 98  598 463  HOH HOH G . 
O 2 HOH 99  599 579  HOH HOH G . 
O 2 HOH 100 600 762  HOH HOH G . 
O 2 HOH 101 601 578  HOH HOH G . 
O 2 HOH 102 602 958  HOH HOH G . 
O 2 HOH 103 603 181  HOH HOH G . 
O 2 HOH 104 604 281  HOH HOH G . 
O 2 HOH 105 605 275  HOH HOH G . 
O 2 HOH 106 606 1276 HOH HOH G . 
O 2 HOH 107 607 218  HOH HOH G . 
O 2 HOH 108 608 231  HOH HOH G . 
O 2 HOH 109 609 1126 HOH HOH G . 
O 2 HOH 110 610 717  HOH HOH G . 
O 2 HOH 111 611 208  HOH HOH G . 
O 2 HOH 112 612 245  HOH HOH G . 
O 2 HOH 113 613 1170 HOH HOH G . 
O 2 HOH 114 614 846  HOH HOH G . 
O 2 HOH 115 615 458  HOH HOH G . 
O 2 HOH 116 616 363  HOH HOH G . 
O 2 HOH 117 617 997  HOH HOH G . 
O 2 HOH 118 618 756  HOH HOH G . 
O 2 HOH 119 619 1072 HOH HOH G . 
O 2 HOH 120 620 725  HOH HOH G . 
O 2 HOH 121 621 693  HOH HOH G . 
O 2 HOH 122 622 339  HOH HOH G . 
O 2 HOH 123 623 983  HOH HOH G . 
O 2 HOH 124 624 985  HOH HOH G . 
O 2 HOH 125 625 1059 HOH HOH G . 
O 2 HOH 126 626 605  HOH HOH G . 
O 2 HOH 127 627 1442 HOH HOH G . 
O 2 HOH 128 628 1237 HOH HOH G . 
O 2 HOH 129 629 451  HOH HOH G . 
O 2 HOH 130 630 709  HOH HOH G . 
O 2 HOH 131 631 1164 HOH HOH G . 
O 2 HOH 132 632 529  HOH HOH G . 
O 2 HOH 133 633 140  HOH HOH G . 
O 2 HOH 134 634 424  HOH HOH G . 
O 2 HOH 135 635 1343 HOH HOH G . 
O 2 HOH 136 636 347  HOH HOH G . 
O 2 HOH 137 637 374  HOH HOH G . 
O 2 HOH 138 638 1142 HOH HOH G . 
O 2 HOH 139 639 900  HOH HOH G . 
O 2 HOH 140 640 1445 HOH HOH G . 
O 2 HOH 141 641 1290 HOH HOH G . 
O 2 HOH 142 642 1321 HOH HOH G . 
O 2 HOH 143 643 843  HOH HOH G . 
O 2 HOH 144 644 1392 HOH HOH G . 
O 2 HOH 145 645 1313 HOH HOH G . 
O 2 HOH 146 646 1052 HOH HOH G . 
O 2 HOH 147 647 628  HOH HOH G . 
O 2 HOH 148 648 1438 HOH HOH G . 
O 2 HOH 149 649 1149 HOH HOH G . 
O 2 HOH 150 650 988  HOH HOH G . 
O 2 HOH 151 651 289  HOH HOH G . 
O 2 HOH 152 652 1157 HOH HOH G . 
O 2 HOH 153 653 473  HOH HOH G . 
O 2 HOH 154 654 308  HOH HOH G . 
O 2 HOH 155 655 641  HOH HOH G . 
O 2 HOH 156 656 401  HOH HOH G . 
O 2 HOH 157 657 908  HOH HOH G . 
O 2 HOH 158 658 836  HOH HOH G . 
O 2 HOH 159 659 618  HOH HOH G . 
O 2 HOH 160 660 1424 HOH HOH G . 
O 2 HOH 161 661 929  HOH HOH G . 
O 2 HOH 162 662 1176 HOH HOH G . 
O 2 HOH 163 663 1173 HOH HOH G . 
O 2 HOH 164 664 477  HOH HOH G . 
O 2 HOH 165 665 738  HOH HOH G . 
O 2 HOH 166 666 750  HOH HOH G . 
O 2 HOH 167 667 763  HOH HOH G . 
O 2 HOH 168 668 1153 HOH HOH G . 
O 2 HOH 169 669 1278 HOH HOH G . 
O 2 HOH 170 670 513  HOH HOH G . 
O 2 HOH 171 671 1432 HOH HOH G . 
O 2 HOH 172 672 1211 HOH HOH G . 
O 2 HOH 173 673 1433 HOH HOH G . 
O 2 HOH 174 674 1355 HOH HOH G . 
O 2 HOH 175 675 1388 HOH HOH G . 
O 2 HOH 176 676 1212 HOH HOH G . 
O 2 HOH 177 677 810  HOH HOH G . 
O 2 HOH 178 678 1245 HOH HOH G . 
O 2 HOH 179 679 1434 HOH HOH G . 
O 2 HOH 180 680 1267 HOH HOH G . 
O 2 HOH 181 681 695  HOH HOH G . 
O 2 HOH 182 682 1315 HOH HOH G . 
O 2 HOH 183 683 1131 HOH HOH G . 
O 2 HOH 184 684 1431 HOH HOH G . 
O 2 HOH 185 685 1220 HOH HOH G . 
O 2 HOH 186 686 1435 HOH HOH G . 
O 2 HOH 187 687 574  HOH HOH G . 
O 2 HOH 188 688 1044 HOH HOH G . 
O 2 HOH 189 689 1154 HOH HOH G . 
O 2 HOH 190 690 55   HOH HOH G . 
O 2 HOH 191 691 860  HOH HOH G . 
P 2 HOH 1   501 1255 HOH HOH H . 
P 2 HOH 2   502 403  HOH HOH H . 
P 2 HOH 3   503 81   HOH HOH H . 
P 2 HOH 4   504 666  HOH HOH H . 
P 2 HOH 5   505 690  HOH HOH H . 
P 2 HOH 6   506 101  HOH HOH H . 
P 2 HOH 7   507 1069 HOH HOH H . 
P 2 HOH 8   508 784  HOH HOH H . 
P 2 HOH 9   509 505  HOH HOH H . 
P 2 HOH 10  510 1259 HOH HOH H . 
P 2 HOH 11  511 877  HOH HOH H . 
P 2 HOH 12  512 880  HOH HOH H . 
P 2 HOH 13  513 699  HOH HOH H . 
P 2 HOH 14  514 594  HOH HOH H . 
P 2 HOH 15  515 663  HOH HOH H . 
P 2 HOH 16  516 1314 HOH HOH H . 
P 2 HOH 17  517 1109 HOH HOH H . 
P 2 HOH 18  518 521  HOH HOH H . 
P 2 HOH 19  519 1040 HOH HOH H . 
P 2 HOH 20  520 26   HOH HOH H . 
P 2 HOH 21  521 639  HOH HOH H . 
P 2 HOH 22  522 306  HOH HOH H . 
P 2 HOH 23  523 29   HOH HOH H . 
P 2 HOH 24  524 350  HOH HOH H . 
P 2 HOH 25  525 864  HOH HOH H . 
P 2 HOH 26  526 682  HOH HOH H . 
P 2 HOH 27  527 1365 HOH HOH H . 
P 2 HOH 28  528 159  HOH HOH H . 
P 2 HOH 29  529 812  HOH HOH H . 
P 2 HOH 30  530 361  HOH HOH H . 
P 2 HOH 31  531 1129 HOH HOH H . 
P 2 HOH 32  532 124  HOH HOH H . 
P 2 HOH 33  533 1350 HOH HOH H . 
P 2 HOH 34  534 213  HOH HOH H . 
P 2 HOH 35  535 196  HOH HOH H . 
P 2 HOH 36  536 1299 HOH HOH H . 
P 2 HOH 37  537 153  HOH HOH H . 
P 2 HOH 38  538 301  HOH HOH H . 
P 2 HOH 39  539 309  HOH HOH H . 
P 2 HOH 40  540 745  HOH HOH H . 
P 2 HOH 41  541 948  HOH HOH H . 
P 2 HOH 42  542 399  HOH HOH H . 
P 2 HOH 43  543 426  HOH HOH H . 
P 2 HOH 44  544 125  HOH HOH H . 
P 2 HOH 45  545 412  HOH HOH H . 
P 2 HOH 46  546 60   HOH HOH H . 
P 2 HOH 47  547 86   HOH HOH H . 
P 2 HOH 48  548 902  HOH HOH H . 
P 2 HOH 49  549 331  HOH HOH H . 
P 2 HOH 50  550 1412 HOH HOH H . 
P 2 HOH 51  551 133  HOH HOH H . 
P 2 HOH 52  552 1008 HOH HOH H . 
P 2 HOH 53  553 1005 HOH HOH H . 
P 2 HOH 54  554 69   HOH HOH H . 
P 2 HOH 55  555 34   HOH HOH H . 
P 2 HOH 56  556 677  HOH HOH H . 
P 2 HOH 57  557 1440 HOH HOH H . 
P 2 HOH 58  558 423  HOH HOH H . 
P 2 HOH 59  559 397  HOH HOH H . 
P 2 HOH 60  560 705  HOH HOH H . 
P 2 HOH 61  561 761  HOH HOH H . 
P 2 HOH 62  562 205  HOH HOH H . 
P 2 HOH 63  563 262  HOH HOH H . 
P 2 HOH 64  564 1032 HOH HOH H . 
P 2 HOH 65  565 669  HOH HOH H . 
P 2 HOH 66  566 84   HOH HOH H . 
P 2 HOH 67  567 284  HOH HOH H . 
P 2 HOH 68  568 353  HOH HOH H . 
P 2 HOH 69  569 269  HOH HOH H . 
P 2 HOH 70  570 889  HOH HOH H . 
P 2 HOH 71  571 225  HOH HOH H . 
P 2 HOH 72  572 210  HOH HOH H . 
P 2 HOH 73  573 789  HOH HOH H . 
P 2 HOH 74  574 901  HOH HOH H . 
P 2 HOH 75  575 585  HOH HOH H . 
P 2 HOH 76  576 49   HOH HOH H . 
P 2 HOH 77  577 310  HOH HOH H . 
P 2 HOH 78  578 1373 HOH HOH H . 
P 2 HOH 79  579 118  HOH HOH H . 
P 2 HOH 80  580 876  HOH HOH H . 
P 2 HOH 81  581 325  HOH HOH H . 
P 2 HOH 82  582 707  HOH HOH H . 
P 2 HOH 83  583 839  HOH HOH H . 
P 2 HOH 84  584 1232 HOH HOH H . 
P 2 HOH 85  585 96   HOH HOH H . 
P 2 HOH 86  586 460  HOH HOH H . 
P 2 HOH 87  587 790  HOH HOH H . 
P 2 HOH 88  588 1449 HOH HOH H . 
P 2 HOH 89  589 1124 HOH HOH H . 
P 2 HOH 90  590 295  HOH HOH H . 
P 2 HOH 91  591 467  HOH HOH H . 
P 2 HOH 92  592 757  HOH HOH H . 
P 2 HOH 93  593 224  HOH HOH H . 
P 2 HOH 94  594 180  HOH HOH H . 
P 2 HOH 95  595 507  HOH HOH H . 
P 2 HOH 96  596 730  HOH HOH H . 
P 2 HOH 97  597 383  HOH HOH H . 
P 2 HOH 98  598 557  HOH HOH H . 
P 2 HOH 99  599 416  HOH HOH H . 
P 2 HOH 100 600 534  HOH HOH H . 
P 2 HOH 101 601 1079 HOH HOH H . 
P 2 HOH 102 602 835  HOH HOH H . 
P 2 HOH 103 603 883  HOH HOH H . 
P 2 HOH 104 604 407  HOH HOH H . 
P 2 HOH 105 605 992  HOH HOH H . 
P 2 HOH 106 606 230  HOH HOH H . 
P 2 HOH 107 607 40   HOH HOH H . 
P 2 HOH 108 608 662  HOH HOH H . 
P 2 HOH 109 609 1201 HOH HOH H . 
P 2 HOH 110 610 708  HOH HOH H . 
P 2 HOH 111 611 719  HOH HOH H . 
P 2 HOH 112 612 214  HOH HOH H . 
P 2 HOH 113 613 916  HOH HOH H . 
P 2 HOH 114 614 1181 HOH HOH H . 
P 2 HOH 115 615 931  HOH HOH H . 
P 2 HOH 116 616 1311 HOH HOH H . 
P 2 HOH 117 617 659  HOH HOH H . 
P 2 HOH 118 618 943  HOH HOH H . 
P 2 HOH 119 619 413  HOH HOH H . 
P 2 HOH 120 620 170  HOH HOH H . 
P 2 HOH 121 621 1401 HOH HOH H . 
P 2 HOH 122 622 447  HOH HOH H . 
P 2 HOH 123 623 778  HOH HOH H . 
P 2 HOH 124 624 779  HOH HOH H . 
P 2 HOH 125 625 211  HOH HOH H . 
P 2 HOH 126 626 419  HOH HOH H . 
P 2 HOH 127 627 1254 HOH HOH H . 
P 2 HOH 128 628 998  HOH HOH H . 
P 2 HOH 129 629 869  HOH HOH H . 
P 2 HOH 130 630 47   HOH HOH H . 
P 2 HOH 131 631 582  HOH HOH H . 
P 2 HOH 132 632 1108 HOH HOH H . 
P 2 HOH 133 633 1055 HOH HOH H . 
P 2 HOH 134 634 524  HOH HOH H . 
P 2 HOH 135 635 531  HOH HOH H . 
P 2 HOH 136 636 748  HOH HOH H . 
P 2 HOH 137 637 204  HOH HOH H . 
P 2 HOH 138 638 1182 HOH HOH H . 
P 2 HOH 139 639 933  HOH HOH H . 
P 2 HOH 140 640 387  HOH HOH H . 
P 2 HOH 141 641 1443 HOH HOH H . 
P 2 HOH 142 642 1047 HOH HOH H . 
P 2 HOH 143 643 914  HOH HOH H . 
P 2 HOH 144 644 1063 HOH HOH H . 
P 2 HOH 145 645 1324 HOH HOH H . 
P 2 HOH 146 646 623  HOH HOH H . 
P 2 HOH 147 647 59   HOH HOH H . 
P 2 HOH 148 648 1222 HOH HOH H . 
P 2 HOH 149 649 1371 HOH HOH H . 
P 2 HOH 150 650 678  HOH HOH H . 
P 2 HOH 151 651 777  HOH HOH H . 
P 2 HOH 152 652 773  HOH HOH H . 
P 2 HOH 153 653 859  HOH HOH H . 
P 2 HOH 154 654 1070 HOH HOH H . 
P 2 HOH 155 655 1171 HOH HOH H . 
P 2 HOH 156 656 351  HOH HOH H . 
P 2 HOH 157 657 1249 HOH HOH H . 
P 2 HOH 158 658 294  HOH HOH H . 
P 2 HOH 159 659 1271 HOH HOH H . 
P 2 HOH 160 660 963  HOH HOH H . 
P 2 HOH 161 661 794  HOH HOH H . 
P 2 HOH 162 662 1242 HOH HOH H . 
P 2 HOH 163 663 622  HOH HOH H . 
P 2 HOH 164 664 767  HOH HOH H . 
P 2 HOH 165 665 774  HOH HOH H . 
P 2 HOH 166 666 999  HOH HOH H . 
P 2 HOH 167 667 376  HOH HOH H . 
P 2 HOH 168 668 1346 HOH HOH H . 
P 2 HOH 169 669 870  HOH HOH H . 
P 2 HOH 170 670 1178 HOH HOH H . 
P 2 HOH 171 671 857  HOH HOH H . 
P 2 HOH 172 672 1064 HOH HOH H . 
P 2 HOH 173 673 429  HOH HOH H . 
P 2 HOH 174 674 753  HOH HOH H . 
P 2 HOH 175 675 1200 HOH HOH H . 
P 2 HOH 176 676 90   HOH HOH H . 
P 2 HOH 177 677 811  HOH HOH H . 
P 2 HOH 178 678 1071 HOH HOH H . 
P 2 HOH 179 679 806  HOH HOH H . 
P 2 HOH 180 680 1244 HOH HOH H . 
P 2 HOH 181 681 917  HOH HOH H . 
P 2 HOH 182 682 77   HOH HOH H . 
P 2 HOH 183 683 868  HOH HOH H . 
P 2 HOH 184 684 847  HOH HOH H . 
P 2 HOH 185 685 758  HOH HOH H . 
P 2 HOH 186 686 1297 HOH HOH H . 
P 2 HOH 187 687 334  HOH HOH H . 
P 2 HOH 188 688 1287 HOH HOH H . 
P 2 HOH 189 689 1420 HOH HOH H . 
P 2 HOH 190 690 906  HOH HOH H . 
P 2 HOH 191 691 1332 HOH HOH H . 
P 2 HOH 192 692 1352 HOH HOH H . 
P 2 HOH 193 693 1316 HOH HOH H . 
P 2 HOH 194 694 1240 HOH HOH H . 
P 2 HOH 195 695 1320 HOH HOH H . 
P 2 HOH 196 696 444  HOH HOH H . 
P 2 HOH 197 697 1364 HOH HOH H . 
P 2 HOH 198 698 1351 HOH HOH H . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? '(1.19.2_4158: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .                    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .                    4 
# 
_cell.angle_alpha                  99.54 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   101.88 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  115.94 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8YND 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     87.928 
_cell.length_a_esd                 ? 
_cell.length_b                     100.641 
_cell.length_b_esd                 ? 
_cell.length_c                     131.555 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8YND 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8YND 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.49 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          50.62 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'MgCl2.6H2O, Trisodium citrate dihydrate, Bis-Tris-Propane PH7.5, PEG Smear High' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'STFC Large Pixel Detector' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-09-10 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97915 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL18U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97915 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL18U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8YND 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.19 
_reflns.d_resolution_low                               50 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     188982 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.3 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          5.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.869 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.123 
_reflns.pdbx_Rpim_I_all                                0.065 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.982 
_reflns.pdbx_CC_star                                   0.995 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.104 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
2.20 2.24  ? ? ? ? ? ? 9439 ? ? ? ? ? ? ? ? ? ? ? 3.4 0.935 ? ? 0.873 0.466 ? 1  1 0.603 0.867 ? 97.4 ? 0.734 ? ? ? ? ? ? ? ? ? 
2.24 2.28  ? ? ? ? ? ? 9317 ? ? ? ? ? ? ? ? ? ? ? 3.3 0.950 ? ? 0.765 0.416 ? 2  1 0.662 0.892 ? 97.4 ? 0.637 ? ? ? ? ? ? ? ? ? 
2.28 2.32  ? ? ? ? ? ? 9349 ? ? ? ? ? ? ? ? ? ? ? 3.5 0.941 ? ? 0.683 0.357 ? 3  1 0.734 0.920 ? 97.5 ? 0.579 ? ? ? ? ? ? ? ? ? 
2.32 2.37  ? ? ? ? ? ? 9436 ? ? ? ? ? ? ? ? ? ? ? 3.6 0.951 ? ? 0.596 0.310 ? 4  1 0.801 0.943 ? 97.6 ? 0.507 ? ? ? ? ? ? ? ? ? 
2.37 2.42  ? ? ? ? ? ? 9340 ? ? ? ? ? ? ? ? ? ? ? 3.6 0.929 ? ? 0.575 0.299 ? 5  1 0.793 0.940 ? 97.7 ? 0.489 ? ? ? ? ? ? ? ? ? 
2.42 2.48  ? ? ? ? ? ? 9380 ? ? ? ? ? ? ? ? ? ? ? 3.6 0.946 ? ? 0.486 0.254 ? 6  1 0.847 0.958 ? 97.8 ? 0.413 ? ? ? ? ? ? ? ? ? 
2.48 2.54  ? ? ? ? ? ? 9405 ? ? ? ? ? ? ? ? ? ? ? 3.6 0.972 ? ? 0.418 0.217 ? 7  1 0.854 0.960 ? 97.9 ? 0.355 ? ? ? ? ? ? ? ? ? 
2.54 2.61  ? ? ? ? ? ? 9402 ? ? ? ? ? ? ? ? ? ? ? 3.5 0.936 ? ? 0.371 0.196 ? 8  1 0.870 0.965 ? 98.0 ? 0.314 ? ? ? ? ? ? ? ? ? 
2.61 2.69  ? ? ? ? ? ? 9418 ? ? ? ? ? ? ? ? ? ? ? 3.3 0.935 ? ? 0.307 0.167 ? 9  1 0.883 0.969 ? 98.1 ? 0.256 ? ? ? ? ? ? ? ? ? 
2.69 2.77  ? ? ? ? ? ? 9480 ? ? ? ? ? ? ? ? ? ? ? 3.6 0.937 ? ? 0.255 0.133 ? 10 1 0.942 0.985 ? 98.3 ? 0.217 ? ? ? ? ? ? ? ? ? 
2.77 2.87  ? ? ? ? ? ? 9428 ? ? ? ? ? ? ? ? ? ? ? 3.5 0.925 ? ? 0.213 0.111 ? 11 1 0.952 0.988 ? 98.3 ? 0.181 ? ? ? ? ? ? ? ? ? 
2.87 2.99  ? ? ? ? ? ? 9448 ? ? ? ? ? ? ? ? ? ? ? 3.3 0.916 ? ? 0.181 0.097 ? 12 1 0.958 0.989 ? 98.5 ? 0.151 ? ? ? ? ? ? ? ? ? 
2.99 3.12  ? ? ? ? ? ? 9553 ? ? ? ? ? ? ? ? ? ? ? 3.6 0.912 ? ? 0.146 0.076 ? 13 1 0.973 0.993 ? 98.6 ? 0.124 ? ? ? ? ? ? ? ? ? 
3.12 3.29  ? ? ? ? ? ? 9401 ? ? ? ? ? ? ? ? ? ? ? 3.6 0.896 ? ? 0.116 0.060 ? 14 1 0.981 0.995 ? 98.7 ? 0.099 ? ? ? ? ? ? ? ? ? 
3.29 3.49  ? ? ? ? ? ? 9538 ? ? ? ? ? ? ? ? ? ? ? 3.6 0.883 ? ? 0.092 0.047 ? 15 1 0.985 0.996 ? 98.8 ? 0.078 ? ? ? ? ? ? ? ? ? 
3.49 3.76  ? ? ? ? ? ? 9485 ? ? ? ? ? ? ? ? ? ? ? 3.4 0.840 ? ? 0.074 0.040 ? 16 1 0.984 0.996 ? 99.0 ? 0.063 ? ? ? ? ? ? ? ? ? 
3.76 4.14  ? ? ? ? ? ? 9503 ? ? ? ? ? ? ? ? ? ? ? 3.5 0.790 ? ? 0.064 0.034 ? 17 1 0.987 0.997 ? 99.1 ? 0.055 ? ? ? ? ? ? ? ? ? 
4.14 4.74  ? ? ? ? ? ? 9543 ? ? ? ? ? ? ? ? ? ? ? 3.4 0.712 ? ? 0.056 0.030 ? 18 1 0.988 0.997 ? 99.2 ? 0.047 ? ? ? ? ? ? ? ? ? 
4.74 5.97  ? ? ? ? ? ? 9546 ? ? ? ? ? ? ? ? ? ? ? 3.5 0.583 ? ? 0.053 0.027 ? 19 1 0.989 0.997 ? 99.5 ? 0.045 ? ? ? ? ? ? ? ? ? 
5.97 50.00 ? ? ? ? ? ? 9571 ? ? ? ? ? ? ? ? ? ? ? 3.2 0.456 ? ? 0.041 0.022 ? 20 1 0.991 0.998 ? 99.6 ? 0.034 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8YND 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.19 
_refine.ls_d_res_low                             50 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     178967 
_refine.ls_number_reflns_R_free                  8851 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    91.96 
_refine.ls_percent_reflns_R_free                 4.95 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2139 
_refine.ls_R_factor_R_free                       0.2628 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2114 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.96 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      AlphaFold 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.87 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.32 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.19 
_refine_hist.d_res_low                        50 
_refine_hist.number_atoms_solvent             1455 
_refine_hist.number_atoms_total               27012 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        25557 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008 ? 26080 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.055 ? 35419 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 8.148 ? 3590  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.056 ? 3979  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.012 ? 4653  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.19 2.22  . . 125 2168 36.00 . . . . 0.2562 . . . . . . . . . . . 0.3352 
'X-RAY DIFFRACTION' 2.22 2.24  . . 186 3936 63.00 . . . . 0.2512 . . . . . . . . . . . 0.3166 
'X-RAY DIFFRACTION' 2.24 2.27  . . 197 4025 65.00 . . . . 0.2528 . . . . . . . . . . . 0.3318 
'X-RAY DIFFRACTION' 2.27 2.30  . . 230 4514 73.00 . . . . 0.2545 . . . . . . . . . . . 0.3009 
'X-RAY DIFFRACTION' 2.30 2.33  . . 270 5101 83.00 . . . . 0.2490 . . . . . . . . . . . 0.3242 
'X-RAY DIFFRACTION' 2.33 2.36  . . 276 5440 89.00 . . . . 0.2389 . . . . . . . . . . . 0.3585 
'X-RAY DIFFRACTION' 2.36 2.40  . . 277 5797 93.00 . . . . 0.2523 . . . . . . . . . . . 0.3209 
'X-RAY DIFFRACTION' 2.40 2.43  . . 298 5780 95.00 . . . . 0.2470 . . . . . . . . . . . 0.3019 
'X-RAY DIFFRACTION' 2.43 2.47  . . 304 5864 95.00 . . . . 0.2437 . . . . . . . . . . . 0.3328 
'X-RAY DIFFRACTION' 2.47 2.51  . . 302 6016 96.00 . . . . 0.2411 . . . . . . . . . . . 0.3143 
'X-RAY DIFFRACTION' 2.51 2.55  . . 310 5875 96.00 . . . . 0.2371 . . . . . . . . . . . 0.3106 
'X-RAY DIFFRACTION' 2.55 2.60  . . 296 6003 97.00 . . . . 0.2433 . . . . . . . . . . . 0.3079 
'X-RAY DIFFRACTION' 2.60 2.65  . . 313 6152 98.00 . . . . 0.2593 . . . . . . . . . . . 0.3064 
'X-RAY DIFFRACTION' 2.65 2.70  . . 317 6018 98.00 . . . . 0.2623 . . . . . . . . . . . 0.3182 
'X-RAY DIFFRACTION' 2.70 2.76  . . 320 6030 98.00 . . . . 0.2390 . . . . . . . . . . . 0.3331 
'X-RAY DIFFRACTION' 2.76 2.83  . . 326 6041 98.00 . . . . 0.2297 . . . . . . . . . . . 0.2954 
'X-RAY DIFFRACTION' 2.83 2.90  . . 307 6058 98.00 . . . . 0.2302 . . . . . . . . . . . 0.3073 
'X-RAY DIFFRACTION' 2.90 2.98  . . 338 6100 98.00 . . . . 0.2307 . . . . . . . . . . . 0.2893 
'X-RAY DIFFRACTION' 2.98 3.06  . . 318 6042 99.00 . . . . 0.2230 . . . . . . . . . . . 0.2891 
'X-RAY DIFFRACTION' 3.06 3.16  . . 322 6095 99.00 . . . . 0.2248 . . . . . . . . . . . 0.2779 
'X-RAY DIFFRACTION' 3.16 3.28  . . 312 6088 99.00 . . . . 0.2206 . . . . . . . . . . . 0.2679 
'X-RAY DIFFRACTION' 3.28 3.41  . . 303 6091 99.00 . . . . 0.2074 . . . . . . . . . . . 0.2507 
'X-RAY DIFFRACTION' 3.41 3.56  . . 341 6094 99.00 . . . . 0.2024 . . . . . . . . . . . 0.2512 
'X-RAY DIFFRACTION' 3.56 3.75  . . 338 6094 99.00 . . . . 0.1958 . . . . . . . . . . . 0.2533 
'X-RAY DIFFRACTION' 3.75 3.98  . . 329 6081 99.00 . . . . 0.1887 . . . . . . . . . . . 0.2232 
'X-RAY DIFFRACTION' 3.98 4.29  . . 327 6066 99.00 . . . . 0.1868 . . . . . . . . . . . 0.2238 
'X-RAY DIFFRACTION' 4.29 4.72  . . 322 6144 99.00 . . . . 0.1720 . . . . . . . . . . . 0.2105 
'X-RAY DIFFRACTION' 4.72 5.40  . . 322 6124 99.00 . . . . 0.1779 . . . . . . . . . . . 0.2357 
'X-RAY DIFFRACTION' 5.40 6.80  . . 319 6152 99.00 . . . . 0.2017 . . . . . . . . . . . 0.2355 
'X-RAY DIFFRACTION' 6.80 39.53 . . 306 6127 99.00 . . . . 0.1927 . . . . . . . . . . . 0.2085 
# 
_struct.entry_id                     8YND 
_struct.title                        'ATP-grasp peptide ligase from Streptomyces' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8YND 
_struct_keywords.text            'ATP-grasp enzymes, Peptide ligase, Amide synthase, LIGASE' 
_struct_keywords.pdbx_keywords   LIGASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 1 ? 
H N N 1 ? 
I N N 2 ? 
J N N 2 ? 
K N N 2 ? 
L N N 2 ? 
M N N 2 ? 
N N N 2 ? 
O N N 2 ? 
P N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    8YND 
_struct_ref.pdbx_db_accession          8YND 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8YND A 1 ? 448 ? 8YND 1 ? 448 ? 1 448 
2 1 8YND B 1 ? 448 ? 8YND 1 ? 448 ? 1 448 
3 1 8YND C 1 ? 448 ? 8YND 1 ? 448 ? 1 448 
4 1 8YND D 1 ? 448 ? 8YND 1 ? 448 ? 1 448 
5 1 8YND E 1 ? 448 ? 8YND 1 ? 448 ? 1 448 
6 1 8YND F 1 ? 448 ? 8YND 1 ? 448 ? 1 448 
7 1 8YND G 1 ? 448 ? 8YND 1 ? 448 ? 1 448 
8 1 8YND H 1 ? 448 ? 8YND 1 ? 448 ? 1 448 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? dimeric 2 
2 author_defined_assembly ? dimeric 2 
3 author_defined_assembly ? dimeric 2 
4 author_defined_assembly ? dimeric 2 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,I,J 
2 1 C,K     
2 2 D,L     
3 1 E,M     
3 3 F,N     
4 1 G,O     
4 4 H,P     
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z     1.0000000000 0.0000000000 0.0000000000 0.0000000000  0.0000000000 1.0000000000 
0.0000000000 0.0000000000   0.0000000000 0.0000000000 1.0000000000 0.0000000000 
2 'crystal symmetry operation' 1_545 x,y-1,z   1.0000000000 0.0000000000 0.0000000000 44.0233615997 0.0000000000 1.0000000000 
0.0000000000 -90.5016823847 0.0000000000 0.0000000000 1.0000000000 0.0000000000 
3 'crystal symmetry operation' 1_655 x+1,y,z   1.0000000000 0.0000000000 0.0000000000 87.9280000000 0.0000000000 1.0000000000 
0.0000000000 0.0000000000   0.0000000000 0.0000000000 1.0000000000 0.0000000000 
4 'crystal symmetry operation' 1_665 x+1,y+1,z 1.0000000000 0.0000000000 0.0000000000 43.9046384003 0.0000000000 1.0000000000 
0.0000000000 90.5016823847  0.0000000000 0.0000000000 1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1   AA1 THR A 34  ? ALA A 41  ? THR A 34  ALA A 41  5 ? 8  
HELX_P HELX_P2   AA2 ASP A 56  ? GLY A 66  ? ASP A 56  GLY A 66  1 ? 11 
HELX_P HELX_P3   AA3 ASP A 68  ? VAL A 72  ? ASP A 68  VAL A 72  5 ? 5  
HELX_P HELX_P4   AA4 SER A 82  ? ASP A 88  ? SER A 82  ASP A 88  1 ? 7  
HELX_P HELX_P5   AA5 ASP A 88  ? GLY A 100 ? ASP A 88  GLY A 100 1 ? 13 
HELX_P HELX_P6   AA6 THR A 113 ? LEU A 123 ? THR A 113 LEU A 123 1 ? 11 
HELX_P HELX_P7   AA7 GLY A 130 ? GLN A 136 ? GLY A 130 GLN A 136 1 ? 7  
HELX_P HELX_P8   AA8 ASN A 137 ? ASN A 143 ? ASN A 137 ASN A 143 1 ? 7  
HELX_P HELX_P9   AA9 MET A 144 ? GLY A 156 ? MET A 144 GLY A 156 1 ? 13 
HELX_P HELX_P10  AB1 GLY A 167 ? ILE A 179 ? GLY A 167 ILE A 179 1 ? 13 
HELX_P HELX_P11  AB2 GLN A 222 ? THR A 235 ? GLN A 222 THR A 235 1 ? 14 
HELX_P HELX_P12  AB3 PHE A 299 ? GLY A 317 ? PHE A 299 GLY A 317 1 ? 19 
HELX_P HELX_P13  AB4 GLY A 346 ? GLY A 358 ? GLY A 346 GLY A 358 1 ? 13 
HELX_P HELX_P14  AB5 GLY A 377 ? ALA A 388 ? GLY A 377 ALA A 388 1 ? 12 
HELX_P HELX_P15  AB6 ASP A 421 ? GLY A 437 ? ASP A 421 GLY A 437 1 ? 17 
HELX_P HELX_P16  AB7 ASP B 32  ? ALA B 41  ? ASP B 32  ALA B 41  5 ? 10 
HELX_P HELX_P17  AB8 ASP B 56  ? GLY B 66  ? ASP B 56  GLY B 66  1 ? 11 
HELX_P HELX_P18  AB9 SER B 82  ? GLN B 87  ? SER B 82  GLN B 87  1 ? 6  
HELX_P HELX_P19  AC1 ASP B 88  ? GLY B 100 ? ASP B 88  GLY B 100 1 ? 13 
HELX_P HELX_P20  AC2 THR B 113 ? LEU B 123 ? THR B 113 LEU B 123 1 ? 11 
HELX_P HELX_P21  AC3 GLY B 130 ? GLN B 136 ? GLY B 130 GLN B 136 1 ? 7  
HELX_P HELX_P22  AC4 ASN B 137 ? ASN B 143 ? ASN B 137 ASN B 143 1 ? 7  
HELX_P HELX_P23  AC5 MET B 144 ? GLY B 156 ? MET B 144 GLY B 156 1 ? 13 
HELX_P HELX_P24  AC6 GLY B 167 ? ILE B 179 ? GLY B 167 ILE B 179 1 ? 13 
HELX_P HELX_P25  AC7 ALA B 219 ? ASP B 221 ? ALA B 219 ASP B 221 5 ? 3  
HELX_P HELX_P26  AC8 GLN B 222 ? THR B 235 ? GLN B 222 THR B 235 1 ? 14 
HELX_P HELX_P27  AC9 PHE B 299 ? GLY B 317 ? PHE B 299 GLY B 317 1 ? 19 
HELX_P HELX_P28  AD1 GLY B 346 ? GLY B 358 ? GLY B 346 GLY B 358 1 ? 13 
HELX_P HELX_P29  AD2 ASP B 360 ? ASN B 364 ? ASP B 360 ASN B 364 5 ? 5  
HELX_P HELX_P30  AD3 GLY B 377 ? ALA B 388 ? GLY B 377 ALA B 388 1 ? 12 
HELX_P HELX_P31  AD4 ASP B 421 ? GLY B 437 ? ASP B 421 GLY B 437 1 ? 17 
HELX_P HELX_P32  AD5 ASP C 32  ? ALA C 41  ? ASP C 32  ALA C 41  5 ? 10 
HELX_P HELX_P33  AD6 ASP C 56  ? GLY C 66  ? ASP C 56  GLY C 66  1 ? 11 
HELX_P HELX_P34  AD7 SER C 82  ? ASP C 88  ? SER C 82  ASP C 88  1 ? 7  
HELX_P HELX_P35  AD8 ASP C 88  ? GLY C 100 ? ASP C 88  GLY C 100 1 ? 13 
HELX_P HELX_P36  AD9 THR C 113 ? ASN C 124 ? THR C 113 ASN C 124 1 ? 12 
HELX_P HELX_P37  AE1 GLY C 130 ? GLN C 136 ? GLY C 130 GLN C 136 1 ? 7  
HELX_P HELX_P38  AE2 ASN C 137 ? ASN C 143 ? ASN C 137 ASN C 143 1 ? 7  
HELX_P HELX_P39  AE3 MET C 144 ? LEU C 155 ? MET C 144 LEU C 155 1 ? 12 
HELX_P HELX_P40  AE4 GLY C 167 ? ILE C 179 ? GLY C 167 ILE C 179 1 ? 13 
HELX_P HELX_P41  AE5 GLN C 222 ? THR C 235 ? GLN C 222 THR C 235 1 ? 14 
HELX_P HELX_P42  AE6 PHE C 299 ? GLY C 317 ? PHE C 299 GLY C 317 1 ? 19 
HELX_P HELX_P43  AE7 GLY C 346 ? GLY C 358 ? GLY C 346 GLY C 358 1 ? 13 
HELX_P HELX_P44  AE8 ASP C 360 ? ASN C 364 ? ASP C 360 ASN C 364 5 ? 5  
HELX_P HELX_P45  AE9 GLY C 377 ? ALA C 388 ? GLY C 377 ALA C 388 1 ? 12 
HELX_P HELX_P46  AF1 ASP C 421 ? GLY C 437 ? ASP C 421 GLY C 437 1 ? 17 
HELX_P HELX_P47  AF2 THR D 34  ? ALA D 41  ? THR D 34  ALA D 41  5 ? 8  
HELX_P HELX_P48  AF3 ASP D 56  ? GLY D 66  ? ASP D 56  GLY D 66  1 ? 11 
HELX_P HELX_P49  AF4 ASP D 68  ? VAL D 72  ? ASP D 68  VAL D 72  5 ? 5  
HELX_P HELX_P50  AF5 SER D 82  ? GLN D 87  ? SER D 82  GLN D 87  1 ? 6  
HELX_P HELX_P51  AF6 ASP D 88  ? GLY D 100 ? ASP D 88  GLY D 100 1 ? 13 
HELX_P HELX_P52  AF7 THR D 113 ? ASN D 124 ? THR D 113 ASN D 124 1 ? 12 
HELX_P HELX_P53  AF8 GLY D 130 ? GLN D 136 ? GLY D 130 GLN D 136 1 ? 7  
HELX_P HELX_P54  AF9 ASN D 137 ? ASN D 143 ? ASN D 137 ASN D 143 1 ? 7  
HELX_P HELX_P55  AG1 MET D 144 ? GLY D 156 ? MET D 144 GLY D 156 1 ? 13 
HELX_P HELX_P56  AG2 GLY D 167 ? ILE D 179 ? GLY D 167 ILE D 179 1 ? 13 
HELX_P HELX_P57  AG3 ALA D 219 ? ASP D 221 ? ALA D 219 ASP D 221 5 ? 3  
HELX_P HELX_P58  AG4 GLN D 222 ? THR D 235 ? GLN D 222 THR D 235 1 ? 14 
HELX_P HELX_P59  AG5 PHE D 299 ? GLY D 317 ? PHE D 299 GLY D 317 1 ? 19 
HELX_P HELX_P60  AG6 GLY D 346 ? GLY D 358 ? GLY D 346 GLY D 358 1 ? 13 
HELX_P HELX_P61  AG7 ASP D 360 ? ASN D 364 ? ASP D 360 ASN D 364 5 ? 5  
HELX_P HELX_P62  AG8 GLY D 377 ? GLY D 389 ? GLY D 377 GLY D 389 1 ? 13 
HELX_P HELX_P63  AG9 ASP D 421 ? GLY D 437 ? ASP D 421 GLY D 437 1 ? 17 
HELX_P HELX_P64  AH1 ASN E 8   ? ASP E 12  ? ASN E 8   ASP E 12  5 ? 5  
HELX_P HELX_P65  AH2 THR E 34  ? ALA E 41  ? THR E 34  ALA E 41  5 ? 8  
HELX_P HELX_P66  AH3 ASP E 56  ? GLY E 66  ? ASP E 56  GLY E 66  1 ? 11 
HELX_P HELX_P67  AH4 ASP E 68  ? VAL E 72  ? ASP E 68  VAL E 72  5 ? 5  
HELX_P HELX_P68  AH5 SER E 82  ? ASP E 88  ? SER E 82  ASP E 88  1 ? 7  
HELX_P HELX_P69  AH6 ASP E 88  ? GLY E 100 ? ASP E 88  GLY E 100 1 ? 13 
HELX_P HELX_P70  AH7 THR E 113 ? LEU E 123 ? THR E 113 LEU E 123 1 ? 11 
HELX_P HELX_P71  AH8 GLY E 130 ? GLN E 136 ? GLY E 130 GLN E 136 1 ? 7  
HELX_P HELX_P72  AH9 ASN E 137 ? ASN E 143 ? ASN E 137 ASN E 143 1 ? 7  
HELX_P HELX_P73  AI1 MET E 144 ? GLY E 156 ? MET E 144 GLY E 156 1 ? 13 
HELX_P HELX_P74  AI2 GLY E 167 ? ILE E 179 ? GLY E 167 ILE E 179 1 ? 13 
HELX_P HELX_P75  AI3 GLN E 222 ? THR E 235 ? GLN E 222 THR E 235 1 ? 14 
HELX_P HELX_P76  AI4 PHE E 299 ? GLY E 317 ? PHE E 299 GLY E 317 1 ? 19 
HELX_P HELX_P77  AI5 GLY E 346 ? GLY E 358 ? GLY E 346 GLY E 358 1 ? 13 
HELX_P HELX_P78  AI6 ASP E 360 ? ASN E 364 ? ASP E 360 ASN E 364 5 ? 5  
HELX_P HELX_P79  AI7 GLY E 377 ? ALA E 388 ? GLY E 377 ALA E 388 1 ? 12 
HELX_P HELX_P80  AI8 ASP E 421 ? GLY E 437 ? ASP E 421 GLY E 437 1 ? 17 
HELX_P HELX_P81  AI9 ASP F 32  ? ALA F 41  ? ASP F 32  ALA F 41  5 ? 10 
HELX_P HELX_P82  AJ1 ASP F 56  ? GLY F 66  ? ASP F 56  GLY F 66  1 ? 11 
HELX_P HELX_P83  AJ2 ASP F 68  ? VAL F 72  ? ASP F 68  VAL F 72  5 ? 5  
HELX_P HELX_P84  AJ3 SER F 82  ? ASP F 88  ? SER F 82  ASP F 88  1 ? 7  
HELX_P HELX_P85  AJ4 ASP F 88  ? GLY F 100 ? ASP F 88  GLY F 100 1 ? 13 
HELX_P HELX_P86  AJ5 THR F 113 ? LEU F 123 ? THR F 113 LEU F 123 1 ? 11 
HELX_P HELX_P87  AJ6 GLY F 130 ? GLN F 136 ? GLY F 130 GLN F 136 1 ? 7  
HELX_P HELX_P88  AJ7 ASN F 137 ? LEU F 142 ? ASN F 137 LEU F 142 1 ? 6  
HELX_P HELX_P89  AJ8 MET F 144 ? GLY F 156 ? MET F 144 GLY F 156 1 ? 13 
HELX_P HELX_P90  AJ9 GLY F 167 ? ALA F 180 ? GLY F 167 ALA F 180 1 ? 14 
HELX_P HELX_P91  AK1 ALA F 219 ? ASP F 221 ? ALA F 219 ASP F 221 5 ? 3  
HELX_P HELX_P92  AK2 GLN F 222 ? THR F 235 ? GLN F 222 THR F 235 1 ? 14 
HELX_P HELX_P93  AK3 PHE F 299 ? GLY F 317 ? PHE F 299 GLY F 317 1 ? 19 
HELX_P HELX_P94  AK4 GLY F 346 ? GLY F 358 ? GLY F 346 GLY F 358 1 ? 13 
HELX_P HELX_P95  AK5 ASP F 360 ? ASN F 364 ? ASP F 360 ASN F 364 5 ? 5  
HELX_P HELX_P96  AK6 GLY F 377 ? ALA F 388 ? GLY F 377 ALA F 388 1 ? 12 
HELX_P HELX_P97  AK7 ASP F 421 ? GLY F 437 ? ASP F 421 GLY F 437 1 ? 17 
HELX_P HELX_P98  AK8 ASP G 32  ? ALA G 41  ? ASP G 32  ALA G 41  5 ? 10 
HELX_P HELX_P99  AK9 ASP G 56  ? GLY G 66  ? ASP G 56  GLY G 66  1 ? 11 
HELX_P HELX_P100 AL1 ASP G 68  ? VAL G 72  ? ASP G 68  VAL G 72  5 ? 5  
HELX_P HELX_P101 AL2 SER G 82  ? ASP G 88  ? SER G 82  ASP G 88  1 ? 7  
HELX_P HELX_P102 AL3 ASP G 88  ? GLY G 100 ? ASP G 88  GLY G 100 1 ? 13 
HELX_P HELX_P103 AL4 THR G 113 ? ASN G 124 ? THR G 113 ASN G 124 1 ? 12 
HELX_P HELX_P104 AL5 GLY G 130 ? GLN G 136 ? GLY G 130 GLN G 136 1 ? 7  
HELX_P HELX_P105 AL6 ASN G 137 ? ASN G 143 ? ASN G 137 ASN G 143 1 ? 7  
HELX_P HELX_P106 AL7 MET G 144 ? GLY G 156 ? MET G 144 GLY G 156 1 ? 13 
HELX_P HELX_P107 AL8 GLY G 167 ? ALA G 180 ? GLY G 167 ALA G 180 1 ? 14 
HELX_P HELX_P108 AL9 ALA G 219 ? ASP G 221 ? ALA G 219 ASP G 221 5 ? 3  
HELX_P HELX_P109 AM1 GLN G 222 ? THR G 235 ? GLN G 222 THR G 235 1 ? 14 
HELX_P HELX_P110 AM2 PHE G 299 ? GLY G 317 ? PHE G 299 GLY G 317 1 ? 19 
HELX_P HELX_P111 AM3 GLY G 346 ? GLY G 358 ? GLY G 346 GLY G 358 1 ? 13 
HELX_P HELX_P112 AM4 ASP G 360 ? ASN G 364 ? ASP G 360 ASN G 364 5 ? 5  
HELX_P HELX_P113 AM5 GLY G 377 ? GLY G 389 ? GLY G 377 GLY G 389 1 ? 13 
HELX_P HELX_P114 AM6 ASP G 421 ? GLY G 437 ? ASP G 421 GLY G 437 1 ? 17 
HELX_P HELX_P115 AM7 THR H 34  ? ALA H 41  ? THR H 34  ALA H 41  5 ? 8  
HELX_P HELX_P116 AM8 ASP H 56  ? GLY H 66  ? ASP H 56  GLY H 66  1 ? 11 
HELX_P HELX_P117 AM9 ASP H 68  ? VAL H 72  ? ASP H 68  VAL H 72  5 ? 5  
HELX_P HELX_P118 AN1 SER H 82  ? ASP H 88  ? SER H 82  ASP H 88  1 ? 7  
HELX_P HELX_P119 AN2 ASP H 88  ? GLY H 100 ? ASP H 88  GLY H 100 1 ? 13 
HELX_P HELX_P120 AN3 THR H 113 ? ASN H 124 ? THR H 113 ASN H 124 1 ? 12 
HELX_P HELX_P121 AN4 GLY H 130 ? GLN H 136 ? GLY H 130 GLN H 136 1 ? 7  
HELX_P HELX_P122 AN5 ASN H 137 ? ASN H 143 ? ASN H 137 ASN H 143 1 ? 7  
HELX_P HELX_P123 AN6 MET H 144 ? GLY H 156 ? MET H 144 GLY H 156 1 ? 13 
HELX_P HELX_P124 AN7 GLY H 167 ? ILE H 179 ? GLY H 167 ILE H 179 1 ? 13 
HELX_P HELX_P125 AN8 ALA H 219 ? ASP H 221 ? ALA H 219 ASP H 221 5 ? 3  
HELX_P HELX_P126 AN9 GLN H 222 ? THR H 235 ? GLN H 222 THR H 235 1 ? 14 
HELX_P HELX_P127 AO1 PHE H 299 ? GLY H 317 ? PHE H 299 GLY H 317 1 ? 19 
HELX_P HELX_P128 AO2 GLY H 346 ? GLY H 358 ? GLY H 346 GLY H 358 1 ? 13 
HELX_P HELX_P129 AO3 ASP H 360 ? ASN H 365 ? ASP H 360 ASN H 365 1 ? 6  
HELX_P HELX_P130 AO4 GLY H 377 ? ALA H 388 ? GLY H 377 ALA H 388 1 ? 12 
HELX_P HELX_P131 AO5 ASP H 421 ? GLY H 437 ? ASP H 421 GLY H 437 1 ? 17 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLY 
_struct_mon_prot_cis.label_seq_id           410 
_struct_mon_prot_cis.label_asym_id          B 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLY 
_struct_mon_prot_cis.auth_seq_id            410 
_struct_mon_prot_cis.auth_asym_id           B 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    411 
_struct_mon_prot_cis.pdbx_label_asym_id_2   B 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     411 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    B 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       0.89 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 4 ? 
AA4 ? 2 ? 
AA5 ? 3 ? 
AA6 ? 4 ? 
AA7 ? 5 ? 
AA8 ? 8 ? 
AA9 ? 4 ? 
AB1 ? 5 ? 
AB2 ? 8 ? 
AB3 ? 4 ? 
AB4 ? 5 ? 
AB5 ? 8 ? 
AB6 ? 4 ? 
AB7 ? 5 ? 
AB8 ? 5 ? 
AB9 ? 3 ? 
AC1 ? 4 ? 
AC2 ? 5 ? 
AC3 ? 5 ? 
AC4 ? 3 ? 
AC5 ? 4 ? 
AC6 ? 5 ? 
AC7 ? 4 ? 
AC8 ? 2 ? 
AC9 ? 3 ? 
AD1 ? 4 ? 
AD2 ? 5 ? 
AD3 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA8 6 7 ? anti-parallel 
AA8 7 8 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? parallel      
AA9 3 4 ? parallel      
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB2 5 6 ? anti-parallel 
AB2 6 7 ? anti-parallel 
AB2 7 8 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? parallel      
AB3 3 4 ? parallel      
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? parallel      
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB5 5 6 ? anti-parallel 
AB5 6 7 ? anti-parallel 
AB5 7 8 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? parallel      
AB6 3 4 ? parallel      
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB7 4 5 ? parallel      
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB8 4 5 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AC1 1 2 ? parallel      
AC1 2 3 ? parallel      
AC1 3 4 ? parallel      
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC2 4 5 ? parallel      
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC3 4 5 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC5 1 2 ? parallel      
AC5 2 3 ? parallel      
AC5 3 4 ? parallel      
AC6 1 2 ? anti-parallel 
AC6 2 3 ? anti-parallel 
AC6 3 4 ? anti-parallel 
AC6 4 5 ? parallel      
AC7 1 2 ? anti-parallel 
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC9 1 2 ? anti-parallel 
AC9 2 3 ? anti-parallel 
AD1 1 2 ? parallel      
AD1 2 3 ? parallel      
AD1 3 4 ? parallel      
AD2 1 2 ? anti-parallel 
AD2 2 3 ? anti-parallel 
AD2 3 4 ? anti-parallel 
AD2 4 5 ? parallel      
AD3 1 2 ? anti-parallel 
AD3 2 3 ? anti-parallel 
AD3 3 4 ? anti-parallel 
AD3 4 5 ? anti-parallel 
AD3 5 6 ? anti-parallel 
AD3 6 7 ? anti-parallel 
AD3 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 HIS A 73  ? ARG A 76  ? HIS A 73  ARG A 76  
AA1 2 VAL A 46  ? ILE A 49  ? VAL A 46  ILE A 49  
AA1 3 LYS A 3   ? LEU A 6   ? LYS A 3   LEU A 6   
AA1 4 SER A 106 ? PRO A 109 ? SER A 106 PRO A 109 
AA2 1 GLY A 162 ? ALA A 165 ? GLY A 162 ALA A 165 
AA2 2 ILE A 242 ? THR A 246 ? ILE A 242 THR A 246 
AA2 3 MET A 184 ? GLN A 189 ? MET A 184 GLN A 189 
AA2 4 ASN A 198 ? SER A 202 ? ASN A 198 SER A 202 
AA2 5 GLU A 214 ? ALA A 217 ? GLU A 214 ALA A 217 
AA3 1 ALA A 265 ? SER A 271 ? ALA A 265 SER A 271 
AA3 2 GLN A 252 ? LEU A 260 ? GLN A 252 LEU A 260 
AA3 3 GLY A 320 ? VAL A 328 ? GLY A 320 VAL A 328 
AA3 4 VAL A 334 ? ASN A 340 ? VAL A 334 ASN A 340 
AA4 1 LEU A 273 ? TYR A 275 ? LEU A 273 TYR A 275 
AA4 2 TRP A 288 ? LEU A 291 ? TRP A 288 LEU A 291 
AA5 1 PHE A 366 ? VAL A 373 ? PHE A 366 VAL A 373 
AA5 2 GLY A 412 ? SER A 419 ? GLY A 412 SER A 419 
AA5 3 GLY A 399 ? SER A 407 ? GLY A 399 SER A 407 
AA6 1 HIS B 73  ? ARG B 76  ? HIS B 73  ARG B 76  
AA6 2 VAL B 46  ? ILE B 49  ? VAL B 46  ILE B 49  
AA6 3 LYS B 3   ? LEU B 6   ? LYS B 3   LEU B 6   
AA6 4 SER B 106 ? PRO B 109 ? SER B 106 PRO B 109 
AA7 1 GLY B 162 ? ALA B 165 ? GLY B 162 ALA B 165 
AA7 2 ILE B 242 ? THR B 246 ? ILE B 242 THR B 246 
AA7 3 MET B 184 ? GLN B 189 ? MET B 184 GLN B 189 
AA7 4 ASN B 198 ? SER B 202 ? ASN B 198 SER B 202 
AA7 5 VAL B 215 ? ALA B 217 ? VAL B 215 ALA B 217 
AA8 1 VAL B 334 ? ASN B 340 ? VAL B 334 ASN B 340 
AA8 2 GLY B 320 ? VAL B 328 ? GLY B 320 VAL B 328 
AA8 3 GLN B 252 ? LEU B 260 ? GLN B 252 LEU B 260 
AA8 4 ALA B 265 ? TYR B 275 ? ALA B 265 TYR B 275 
AA8 5 TRP B 288 ? SER B 293 ? TRP B 288 SER B 293 
AA8 6 PHE B 366 ? VAL B 373 ? PHE B 366 VAL B 373 
AA8 7 GLY B 412 ? SER B 419 ? GLY B 412 SER B 419 
AA8 8 GLY B 399 ? SER B 407 ? GLY B 399 SER B 407 
AA9 1 HIS C 73  ? ARG C 76  ? HIS C 73  ARG C 76  
AA9 2 VAL C 46  ? ILE C 49  ? VAL C 46  ILE C 49  
AA9 3 LYS C 3   ? LEU C 6   ? LYS C 3   LEU C 6   
AA9 4 SER C 106 ? PRO C 109 ? SER C 106 PRO C 109 
AB1 1 GLY C 162 ? ALA C 165 ? GLY C 162 ALA C 165 
AB1 2 ILE C 242 ? THR C 246 ? ILE C 242 THR C 246 
AB1 3 MET C 184 ? GLN C 189 ? MET C 184 GLN C 189 
AB1 4 ASN C 198 ? SER C 202 ? ASN C 198 SER C 202 
AB1 5 VAL C 215 ? ALA C 217 ? VAL C 215 ALA C 217 
AB2 1 VAL C 334 ? ASN C 340 ? VAL C 334 ASN C 340 
AB2 2 GLY C 320 ? VAL C 328 ? GLY C 320 VAL C 328 
AB2 3 GLN C 252 ? LEU C 260 ? GLN C 252 LEU C 260 
AB2 4 ALA C 265 ? TYR C 275 ? ALA C 265 TYR C 275 
AB2 5 TRP C 288 ? SER C 293 ? TRP C 288 SER C 293 
AB2 6 PHE C 366 ? VAL C 373 ? PHE C 366 VAL C 373 
AB2 7 GLY C 412 ? SER C 419 ? GLY C 412 SER C 419 
AB2 8 GLY C 399 ? SER C 407 ? GLY C 399 SER C 407 
AB3 1 HIS D 73  ? ARG D 76  ? HIS D 73  ARG D 76  
AB3 2 VAL D 46  ? ILE D 49  ? VAL D 46  ILE D 49  
AB3 3 LYS D 3   ? LEU D 6   ? LYS D 3   LEU D 6   
AB3 4 SER D 106 ? PRO D 109 ? SER D 106 PRO D 109 
AB4 1 GLY D 162 ? ALA D 165 ? GLY D 162 ALA D 165 
AB4 2 ILE D 242 ? THR D 246 ? ILE D 242 THR D 246 
AB4 3 MET D 184 ? GLN D 189 ? MET D 184 GLN D 189 
AB4 4 ASN D 198 ? SER D 202 ? ASN D 198 SER D 202 
AB4 5 GLU D 214 ? ALA D 217 ? GLU D 214 ALA D 217 
AB5 1 VAL D 334 ? ALA D 341 ? VAL D 334 ALA D 341 
AB5 2 GLY D 320 ? VAL D 328 ? GLY D 320 VAL D 328 
AB5 3 GLN D 252 ? LEU D 260 ? GLN D 252 LEU D 260 
AB5 4 ALA D 265 ? TYR D 275 ? ALA D 265 TYR D 275 
AB5 5 TRP D 288 ? SER D 293 ? TRP D 288 SER D 293 
AB5 6 PHE D 366 ? VAL D 373 ? PHE D 366 VAL D 373 
AB5 7 ALA D 413 ? SER D 419 ? ALA D 413 SER D 419 
AB5 8 GLY D 399 ? GLY D 404 ? GLY D 399 GLY D 404 
AB6 1 HIS E 73  ? ARG E 76  ? HIS E 73  ARG E 76  
AB6 2 VAL E 46  ? ILE E 49  ? VAL E 46  ILE E 49  
AB6 3 LYS E 3   ? LEU E 6   ? LYS E 3   LEU E 6   
AB6 4 SER E 106 ? PRO E 109 ? SER E 106 PRO E 109 
AB7 1 GLY E 162 ? ALA E 165 ? GLY E 162 ALA E 165 
AB7 2 ILE E 242 ? THR E 246 ? ILE E 242 THR E 246 
AB7 3 MET E 184 ? GLN E 189 ? MET E 184 GLN E 189 
AB7 4 ASN E 198 ? SER E 202 ? ASN E 198 SER E 202 
AB7 5 GLU E 214 ? ALA E 217 ? GLU E 214 ALA E 217 
AB8 1 TRP E 288 ? ASP E 292 ? TRP E 288 ASP E 292 
AB8 2 ALA E 265 ? TYR E 275 ? ALA E 265 TYR E 275 
AB8 3 PHE E 254 ? LEU E 260 ? PHE E 254 LEU E 260 
AB8 4 GLY E 320 ? VAL E 328 ? GLY E 320 VAL E 328 
AB8 5 VAL E 334 ? ASN E 340 ? VAL E 334 ASN E 340 
AB9 1 PHE E 366 ? VAL E 373 ? PHE E 366 VAL E 373 
AB9 2 GLY E 412 ? SER E 419 ? GLY E 412 SER E 419 
AB9 3 GLY E 399 ? SER E 407 ? GLY E 399 SER E 407 
AC1 1 HIS F 73  ? ARG F 76  ? HIS F 73  ARG F 76  
AC1 2 VAL F 46  ? ILE F 49  ? VAL F 46  ILE F 49  
AC1 3 LYS F 3   ? LEU F 6   ? LYS F 3   LEU F 6   
AC1 4 SER F 106 ? PRO F 109 ? SER F 106 PRO F 109 
AC2 1 GLY F 162 ? ALA F 165 ? GLY F 162 ALA F 165 
AC2 2 ILE F 242 ? THR F 246 ? ILE F 242 THR F 246 
AC2 3 MET F 184 ? GLN F 189 ? MET F 184 GLN F 189 
AC2 4 ASN F 198 ? SER F 202 ? ASN F 198 SER F 202 
AC2 5 GLU F 214 ? ALA F 217 ? GLU F 214 ALA F 217 
AC3 1 LYS F 287 ? LEU F 291 ? LYS F 287 LEU F 291 
AC3 2 ALA F 265 ? GLU F 276 ? ALA F 265 GLU F 276 
AC3 3 GLN F 252 ? LEU F 260 ? GLN F 252 LEU F 260 
AC3 4 GLY F 320 ? VAL F 328 ? GLY F 320 VAL F 328 
AC3 5 VAL F 334 ? ASN F 340 ? VAL F 334 ASN F 340 
AC4 1 PHE F 366 ? VAL F 373 ? PHE F 366 VAL F 373 
AC4 2 GLY F 412 ? SER F 419 ? GLY F 412 SER F 419 
AC4 3 GLY F 399 ? SER F 407 ? GLY F 399 SER F 407 
AC5 1 HIS G 73  ? ARG G 76  ? HIS G 73  ARG G 76  
AC5 2 VAL G 46  ? ILE G 49  ? VAL G 46  ILE G 49  
AC5 3 LYS G 3   ? LEU G 6   ? LYS G 3   LEU G 6   
AC5 4 SER G 106 ? PRO G 109 ? SER G 106 PRO G 109 
AC6 1 GLY G 162 ? ALA G 165 ? GLY G 162 ALA G 165 
AC6 2 ILE G 242 ? THR G 246 ? ILE G 242 THR G 246 
AC6 3 MET G 184 ? GLN G 189 ? MET G 184 GLN G 189 
AC6 4 ASN G 198 ? SER G 202 ? ASN G 198 SER G 202 
AC6 5 GLU G 214 ? ALA G 217 ? GLU G 214 ALA G 217 
AC7 1 ALA G 265 ? SER G 271 ? ALA G 265 SER G 271 
AC7 2 GLN G 252 ? LEU G 260 ? GLN G 252 LEU G 260 
AC7 3 GLY G 320 ? VAL G 328 ? GLY G 320 VAL G 328 
AC7 4 VAL G 334 ? ASN G 340 ? VAL G 334 ASN G 340 
AC8 1 LEU G 273 ? LYS G 274 ? LEU G 273 LYS G 274 
AC8 2 GLY G 290 ? LEU G 291 ? GLY G 290 LEU G 291 
AC9 1 PHE G 366 ? VAL G 373 ? PHE G 366 VAL G 373 
AC9 2 GLY G 412 ? SER G 419 ? GLY G 412 SER G 419 
AC9 3 GLY G 399 ? SER G 407 ? GLY G 399 SER G 407 
AD1 1 HIS H 73  ? ARG H 76  ? HIS H 73  ARG H 76  
AD1 2 VAL H 46  ? ILE H 49  ? VAL H 46  ILE H 49  
AD1 3 LYS H 3   ? LEU H 6   ? LYS H 3   LEU H 6   
AD1 4 SER H 106 ? PRO H 109 ? SER H 106 PRO H 109 
AD2 1 GLY H 162 ? ALA H 165 ? GLY H 162 ALA H 165 
AD2 2 ILE H 242 ? THR H 246 ? ILE H 242 THR H 246 
AD2 3 MET H 184 ? GLN H 189 ? MET H 184 GLN H 189 
AD2 4 ASN H 198 ? SER H 202 ? ASN H 198 SER H 202 
AD2 5 GLU H 214 ? ALA H 217 ? GLU H 214 ALA H 217 
AD3 1 VAL H 334 ? ALA H 341 ? VAL H 334 ALA H 341 
AD3 2 GLY H 320 ? VAL H 328 ? GLY H 320 VAL H 328 
AD3 3 GLN H 252 ? LEU H 260 ? GLN H 252 LEU H 260 
AD3 4 ALA H 265 ? TYR H 275 ? ALA H 265 TYR H 275 
AD3 5 TRP H 288 ? SER H 293 ? TRP H 288 SER H 293 
AD3 6 PHE H 366 ? VAL H 373 ? PHE H 366 VAL H 373 
AD3 7 GLY H 412 ? SER H 419 ? GLY H 412 SER H 419 
AD3 8 GLY H 399 ? SER H 407 ? GLY H 399 SER H 407 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O HIS A 73  ? O HIS A 73  N LEU A 47  ? N LEU A 47  
AA1 2 3 O VAL A 46  ? O VAL A 46  N ILE A 5   ? N ILE A 5   
AA1 3 4 N ILE A 4   ? N ILE A 4   O PHE A 108 ? O PHE A 108 
AA2 1 2 N ALA A 165 ? N ALA A 165 O ILE A 242 ? O ILE A 242 
AA2 2 3 O GLU A 245 ? O GLU A 245 N ILE A 186 ? N ILE A 186 
AA2 3 4 N VAL A 185 ? N VAL A 185 O ILE A 201 ? O ILE A 201 
AA2 4 5 N GLY A 200 ? N GLY A 200 O GLU A 214 ? O GLU A 214 
AA3 1 2 O LEU A 268 ? O LEU A 268 N GLU A 257 ? N GLU A 257 
AA3 2 3 N TYR A 258 ? N TYR A 258 O VAL A 322 ? O VAL A 322 
AA3 3 4 N ILE A 327 ? N ILE A 327 O PHE A 335 ? O PHE A 335 
AA4 1 2 N LYS A 274 ? N LYS A 274 O GLY A 290 ? O GLY A 290 
AA5 1 2 N SER A 368 ? N SER A 368 O VAL A 417 ? O VAL A 417 
AA5 2 3 O GLY A 412 ? O GLY A 412 N SER A 407 ? N SER A 407 
AA6 1 2 O HIS B 73  ? O HIS B 73  N LEU B 47  ? N LEU B 47  
AA6 2 3 O VAL B 46  ? O VAL B 46  N ILE B 5   ? N ILE B 5   
AA6 3 4 N ILE B 4   ? N ILE B 4   O PHE B 108 ? O PHE B 108 
AA7 1 2 N VAL B 163 ? N VAL B 163 O VAL B 244 ? O VAL B 244 
AA7 2 3 O GLU B 245 ? O GLU B 245 N ILE B 186 ? N ILE B 186 
AA7 3 4 N VAL B 185 ? N VAL B 185 O ILE B 201 ? O ILE B 201 
AA7 4 5 N GLY B 200 ? N GLY B 200 O LEU B 216 ? O LEU B 216 
AA8 1 2 O PHE B 335 ? O PHE B 335 N ILE B 327 ? N ILE B 327 
AA8 2 3 O GLY B 320 ? O GLY B 320 N LEU B 260 ? N LEU B 260 
AA8 3 4 N HIS B 259 ? N HIS B 259 O ARG B 266 ? O ARG B 266 
AA8 4 5 N LYS B 274 ? N LYS B 274 O ILE B 289 ? O ILE B 289 
AA8 5 6 N SER B 293 ? N SER B 293 O PHE B 367 ? O PHE B 367 
AA8 6 7 N PHE B 366 ? N PHE B 366 O SER B 419 ? O SER B 419 
AA8 7 8 O GLY B 412 ? O GLY B 412 N SER B 407 ? N SER B 407 
AA9 1 2 O HIS C 73  ? O HIS C 73  N LEU C 47  ? N LEU C 47  
AA9 2 3 O VAL C 46  ? O VAL C 46  N ILE C 5   ? N ILE C 5   
AA9 3 4 N ILE C 4   ? N ILE C 4   O PHE C 108 ? O PHE C 108 
AB1 1 2 N ALA C 165 ? N ALA C 165 O ILE C 242 ? O ILE C 242 
AB1 2 3 O GLU C 245 ? O GLU C 245 N ILE C 186 ? N ILE C 186 
AB1 3 4 N ALA C 187 ? N ALA C 187 O ILE C 199 ? O ILE C 199 
AB1 4 5 N GLY C 200 ? N GLY C 200 O LEU C 216 ? O LEU C 216 
AB2 1 2 O HIS C 337 ? O HIS C 337 N ASP C 325 ? N ASP C 325 
AB2 2 3 O VAL C 322 ? O VAL C 322 N TYR C 258 ? N TYR C 258 
AB2 3 4 N GLU C 257 ? N GLU C 257 O LEU C 268 ? O LEU C 268 
AB2 4 5 N ILE C 272 ? N ILE C 272 O ASP C 292 ? O ASP C 292 
AB2 5 6 N LEU C 291 ? N LEU C 291 O SER C 369 ? O SER C 369 
AB2 6 7 N PHE C 366 ? N PHE C 366 O SER C 419 ? O SER C 419 
AB2 7 8 O GLY C 412 ? O GLY C 412 N SER C 407 ? N SER C 407 
AB3 1 2 O GLU D 75  ? O GLU D 75  N LEU D 47  ? N LEU D 47  
AB3 2 3 O VAL D 46  ? O VAL D 46  N ILE D 5   ? N ILE D 5   
AB3 3 4 N ILE D 4   ? N ILE D 4   O PHE D 108 ? O PHE D 108 
AB4 1 2 N VAL D 163 ? N VAL D 163 O VAL D 244 ? O VAL D 244 
AB4 2 3 O THR D 243 ? O THR D 243 N LYS D 188 ? N LYS D 188 
AB4 3 4 N VAL D 185 ? N VAL D 185 O ILE D 201 ? O ILE D 201 
AB4 4 5 N SER D 202 ? N SER D 202 O LEU D 216 ? O LEU D 216 
AB5 1 2 O PHE D 335 ? O PHE D 335 N ILE D 327 ? N ILE D 327 
AB5 2 3 O VAL D 322 ? O VAL D 322 N TYR D 258 ? N TYR D 258 
AB5 3 4 N HIS D 259 ? N HIS D 259 O ARG D 266 ? O ARG D 266 
AB5 4 5 N ILE D 272 ? N ILE D 272 O ASP D 292 ? O ASP D 292 
AB5 5 6 N SER D 293 ? N SER D 293 O PHE D 367 ? O PHE D 367 
AB5 6 7 N PHE D 366 ? N PHE D 366 O SER D 419 ? O SER D 419 
AB5 7 8 O PHE D 418 ? O PHE D 418 N GLY D 399 ? N GLY D 399 
AB6 1 2 O GLU E 75  ? O GLU E 75  N LEU E 47  ? N LEU E 47  
AB6 2 3 O VAL E 46  ? O VAL E 46  N ILE E 5   ? N ILE E 5   
AB6 3 4 N ILE E 4   ? N ILE E 4   O PHE E 108 ? O PHE E 108 
AB7 1 2 N ALA E 165 ? N ALA E 165 O ILE E 242 ? O ILE E 242 
AB7 2 3 O THR E 243 ? O THR E 243 N LYS E 188 ? N LYS E 188 
AB7 3 4 N ALA E 187 ? N ALA E 187 O ILE E 199 ? O ILE E 199 
AB7 4 5 N GLY E 200 ? N GLY E 200 O GLU E 214 ? O GLU E 214 
AB8 1 2 O GLY E 290 ? O GLY E 290 N LYS E 274 ? N LYS E 274 
AB8 2 3 O ARG E 266 ? O ARG E 266 N HIS E 259 ? N HIS E 259 
AB8 3 4 N PHE E 254 ? N PHE E 254 O GLY E 326 ? O GLY E 326 
AB8 4 5 N ASP E 325 ? N ASP E 325 O GLU E 338 ? O GLU E 338 
AB9 1 2 N VAL E 373 ? N VAL E 373 O ALA E 413 ? O ALA E 413 
AB9 2 3 O GLY E 412 ? O GLY E 412 N SER E 407 ? N SER E 407 
AC1 1 2 O HIS F 73  ? O HIS F 73  N LEU F 47  ? N LEU F 47  
AC1 2 3 O VAL F 46  ? O VAL F 46  N ILE F 5   ? N ILE F 5   
AC1 3 4 N ILE F 4   ? N ILE F 4   O PHE F 108 ? O PHE F 108 
AC2 1 2 N ALA F 165 ? N ALA F 165 O ILE F 242 ? O ILE F 242 
AC2 2 3 O THR F 243 ? O THR F 243 N LYS F 188 ? N LYS F 188 
AC2 3 4 N ALA F 187 ? N ALA F 187 O ILE F 199 ? O ILE F 199 
AC2 4 5 N GLY F 200 ? N GLY F 200 O LEU F 216 ? O LEU F 216 
AC3 1 2 O GLY F 290 ? O GLY F 290 N LYS F 274 ? N LYS F 274 
AC3 2 3 O ARG F 266 ? O ARG F 266 N HIS F 259 ? N HIS F 259 
AC3 3 4 N TYR F 258 ? N TYR F 258 O VAL F 322 ? O VAL F 322 
AC3 4 5 N ASP F 325 ? N ASP F 325 O HIS F 337 ? O HIS F 337 
AC4 1 2 N PHE F 366 ? N PHE F 366 O SER F 419 ? O SER F 419 
AC4 2 3 O GLY F 412 ? O GLY F 412 N SER F 407 ? N SER F 407 
AC5 1 2 O HIS G 73  ? O HIS G 73  N LEU G 47  ? N LEU G 47  
AC5 2 3 O VAL G 46  ? O VAL G 46  N ILE G 5   ? N ILE G 5   
AC5 3 4 N ILE G 4   ? N ILE G 4   O PHE G 108 ? O PHE G 108 
AC6 1 2 N ALA G 165 ? N ALA G 165 O ILE G 242 ? O ILE G 242 
AC6 2 3 O GLU G 245 ? O GLU G 245 N ILE G 186 ? N ILE G 186 
AC6 3 4 N ALA G 187 ? N ALA G 187 O ILE G 199 ? O ILE G 199 
AC6 4 5 N GLY G 200 ? N GLY G 200 O LEU G 216 ? O LEU G 216 
AC7 1 2 O LEU G 268 ? O LEU G 268 N GLU G 257 ? N GLU G 257 
AC7 2 3 N TYR G 258 ? N TYR G 258 O VAL G 322 ? O VAL G 322 
AC7 3 4 N ASP G 325 ? N ASP G 325 O HIS G 337 ? O HIS G 337 
AC8 1 2 N LYS G 274 ? N LYS G 274 O GLY G 290 ? O GLY G 290 
AC9 1 2 N SER G 368 ? N SER G 368 O VAL G 417 ? O VAL G 417 
AC9 2 3 O GLY G 412 ? O GLY G 412 N SER G 407 ? N SER G 407 
AD1 1 2 O GLU H 75  ? O GLU H 75  N LEU H 47  ? N LEU H 47  
AD1 2 3 O VAL H 46  ? O VAL H 46  N ILE H 5   ? N ILE H 5   
AD1 3 4 N ILE H 4   ? N ILE H 4   O PHE H 108 ? O PHE H 108 
AD2 1 2 N VAL H 163 ? N VAL H 163 O VAL H 244 ? O VAL H 244 
AD2 2 3 O GLU H 245 ? O GLU H 245 N ILE H 186 ? N ILE H 186 
AD2 3 4 N ALA H 187 ? N ALA H 187 O ILE H 199 ? O ILE H 199 
AD2 4 5 N SER H 202 ? N SER H 202 O LEU H 216 ? O LEU H 216 
AD3 1 2 O HIS H 337 ? O HIS H 337 N ASP H 325 ? N ASP H 325 
AD3 2 3 O VAL H 322 ? O VAL H 322 N TYR H 258 ? N TYR H 258 
AD3 3 4 N HIS H 259 ? N HIS H 259 O ARG H 266 ? O ARG H 266 
AD3 4 5 N ILE H 272 ? N ILE H 272 O ASP H 292 ? O ASP H 292 
AD3 5 6 N SER H 293 ? N SER H 293 O PHE H 367 ? O PHE H 367 
AD3 6 7 N VAL H 373 ? N VAL H 373 O ALA H 413 ? O ALA H 413 
AD3 7 8 O GLU H 414 ? O GLU H 414 N LEU H 403 ? N LEU H 403 
# 
_pdbx_entry_details.entry_id                   8YND 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1   1 O   E HOH 554 ? ? O   E HOH 677 ? ? 1.81 
2   1 O   H HOH 624 ? ? O   H HOH 661 ? ? 1.81 
3   1 OE1 G GLU 181 ? ? O   G HOH 501 ? ? 1.81 
4   1 OD1 D ASN 406 ? ? O   D HOH 501 ? ? 1.84 
5   1 O   F HOH 662 ? ? O   F HOH 669 ? ? 1.84 
6   1 O   H HOH 624 ? ? O   H HOH 630 ? ? 1.85 
7   1 NH1 E ARG 213 ? ? O   E HOH 501 ? ? 1.86 
8   1 O   C HOH 610 ? ? O   C HOH 647 ? ? 1.86 
9   1 O   H HOH 510 ? ? O   H HOH 668 ? ? 1.87 
10  1 NH2 E ARG 383 ? ? O   E HOH 502 ? ? 1.87 
11  1 O   F HIS 359 ? ? O   F HOH 501 ? ? 1.88 
12  1 O   E HOH 613 ? ? O   E HOH 669 ? ? 1.89 
13  1 N   D MET 1   ? ? O   D HOH 502 ? ? 1.90 
14  1 OD1 F ASP 360 ? ? O   F HOH 502 ? ? 1.90 
15  1 OE2 H GLU 42  ? ? O   H HOH 501 ? ? 1.90 
16  1 O   F LEU 371 ? ? O   F HOH 503 ? ? 1.90 
17  1 O   A MET 144 ? ? O   A HOH 501 ? ? 1.91 
18  1 O   F HOH 574 ? ? O   F HOH 664 ? ? 1.92 
19  1 O   A HOH 608 ? ? O   F HOH 647 ? ? 1.93 
20  1 O   B HOH 502 ? ? O   B HOH 526 ? ? 1.93 
21  1 NE2 F GLN 176 ? ? O   F HOH 504 ? ? 1.93 
22  1 O   G HOH 584 ? ? O   G HOH 651 ? ? 1.94 
23  1 O   D HOH 616 ? ? O   D HOH 643 ? ? 1.94 
24  1 O   B HOH 656 ? ? O   B HOH 660 ? ? 1.95 
25  1 O   B HOH 507 ? ? O   B HOH 558 ? ? 1.95 
26  1 O   B SER 192 ? ? O   B HOH 501 ? ? 1.95 
27  1 O   H LEU 357 ? ? O   H HOH 502 ? ? 1.95 
28  1 O   E THR 52  ? ? O   E HOH 503 ? ? 1.96 
29  1 OD1 E ASP 325 ? ? O   E HOH 504 ? ? 1.96 
30  1 O   E SER 192 ? ? O   E HOH 505 ? ? 1.96 
31  1 OE2 G GLU 245 ? ? O   G HOH 502 ? ? 1.97 
32  1 O   F HOH 669 ? ? O   F HOH 685 ? ? 1.98 
33  1 OG  C SER 29  ? ? O   C HOH 501 ? ? 1.98 
34  1 O   F SER 295 ? ? O   F HOH 505 ? ? 1.99 
35  1 O   C HOH 646 ? ? O   C HOH 659 ? ? 1.99 
36  1 O   E THR 31  ? ? O   E HOH 503 ? ? 1.99 
37  1 O   F HOH 681 ? ? O   F HOH 687 ? ? 2.00 
38  1 OE1 E GLU 354 ? ? O   E HOH 506 ? ? 2.00 
39  1 O   E HOH 684 ? ? O   E HOH 686 ? ? 2.01 
40  1 O   C ASP 360 ? ? O   C HOH 502 ? ? 2.01 
41  1 O   C SER 30  ? ? O   C HOH 503 ? ? 2.01 
42  1 O   D ASP 261 ? ? O   D HOH 503 ? ? 2.01 
43  1 OD1 A ASN 406 ? ? O   A HOH 502 ? ? 2.02 
44  1 OG1 F THR 434 ? ? O   F HOH 506 ? ? 2.02 
45  1 ND2 B ASN 137 ? ? O   B HOH 502 ? ? 2.02 
46  1 OE2 A GLU 398 ? ? O   A HOH 503 ? ? 2.02 
47  1 NH1 F ARG 94  ? ? O   F HOH 507 ? ? 2.02 
48  1 O   B HOH 645 ? ? O   B HOH 662 ? ? 2.02 
49  1 OE2 C GLU 298 ? ? O   C HOH 504 ? ? 2.02 
50  1 ND2 F ASN 137 ? ? O   F HOH 508 ? ? 2.02 
51  1 O   C HOH 633 ? ? O   C HOH 642 ? ? 2.03 
52  1 OG  A SER 106 ? ? O   A HOH 504 ? ? 2.03 
53  1 O   H PHE 336 ? ? O   H HOH 503 ? ? 2.03 
54  1 OE1 A GLU 75  ? ? O   A HOH 505 ? ? 2.03 
55  1 O   B HOH 633 ? ? O   B HOH 643 ? ? 2.04 
56  1 O   C HOH 517 ? ? O   C HOH 584 ? ? 2.04 
57  1 O   A HOH 683 ? ? O   A HOH 686 ? ? 2.05 
58  1 O   D PRO 55  ? ? O   D HOH 504 ? ? 2.05 
59  1 OG1 D THR 33  ? ? O   D HOH 505 ? ? 2.06 
60  1 OG  H SER 207 ? ? O   H HOH 504 ? ? 2.06 
61  1 O   F HOH 683 ? ? O   F HOH 690 ? ? 2.06 
62  1 O   F HOH 685 ? ? O   F HOH 689 ? ? 2.06 
63  1 O   G HOH 656 ? ? O   G HOH 668 ? ? 2.07 
64  1 O   G HOH 544 ? ? O   G HOH 679 ? ? 2.07 
65  1 O   B HOH 503 ? ? O   B HOH 643 ? ? 2.07 
66  1 O   G HOH 674 ? ? O   G HOH 680 ? ? 2.07 
67  1 O   G HOH 611 ? ? O   G HOH 675 ? ? 2.07 
68  1 O   H HOH 573 ? ? O   H HOH 676 ? ? 2.07 
69  1 O   H PRO 80  ? ? O   H HOH 505 ? ? 2.07 
70  1 O   E HOH 595 ? ? O   E HOH 678 ? ? 2.08 
71  1 OE2 F GLU 245 ? ? O   F HOH 509 ? ? 2.08 
72  1 OE1 G GLN 252 ? ? OG  G SER 297 ? ? 2.08 
73  1 O   H VAL 164 ? ? O   H HOH 506 ? ? 2.08 
74  1 O   B SER 208 ? ? O   B HOH 503 ? ? 2.08 
75  1 O   G HOH 646 ? ? O   G HOH 682 ? ? 2.08 
76  1 O   D HOH 508 ? ? O   D HOH 511 ? ? 2.08 
77  1 N   E GLY 211 ? ? O   E HOH 507 ? ? 2.09 
78  1 OE2 H GLU 354 ? ? O   H HOH 507 ? ? 2.09 
79  1 NH2 F ARG 213 ? ? OE1 F GLN 233 ? ? 2.09 
80  1 OH  G TYR 218 ? ? O   G HOH 503 ? ? 2.09 
81  1 O   F MET 1   ? ? O   F HOH 510 ? ? 2.09 
82  1 O   D GLY 193 ? ? O   D HOH 506 ? ? 2.09 
83  1 O   H HOH 665 ? ? O   H HOH 680 ? ? 2.10 
84  1 NE  F ARG 253 ? ? O   F HOH 511 ? ? 2.10 
85  1 NE2 B GLN 78  ? ? O   B HOH 504 ? ? 2.10 
86  1 OE1 D GLU 300 ? ? O   D HOH 507 ? ? 2.10 
87  1 OE1 H GLU 245 ? ? O   H HOH 508 ? ? 2.10 
88  1 NH1 F ARG 213 ? ? O   F HOH 512 ? ? 2.10 
89  1 NH1 F ARG 333 ? ? O   F HOH 513 ? ? 2.11 
90  1 O   E HOH 584 ? ? O   E HOH 666 ? ? 2.12 
91  1 NH1 A ARG 94  ? ? O   A HOH 506 ? ? 2.12 
92  1 OE2 H GLU 181 ? ? O   H HOH 509 ? ? 2.12 
93  1 O   F HIS 196 ? ? O   F HOH 512 ? ? 2.13 
94  1 O   C HOH 526 ? ? O   D HOH 512 ? ? 2.13 
95  1 OE2 D GLU 245 ? ? O   D HOH 508 ? ? 2.13 
96  1 O   B HOH 561 ? ? O   B HOH 649 ? ? 2.13 
97  1 O   H HOH 538 ? ? O   H HOH 673 ? ? 2.13 
98  1 O   B VAL 374 ? ? O   B HOH 505 ? ? 2.13 
99  1 O   H HOH 586 ? ? O   H HOH 587 ? ? 2.13 
100 1 O   C HOH 584 ? ? O   C HOH 625 ? ? 2.14 
101 1 O   C HOH 521 ? ? O   C HOH 625 ? ? 2.14 
102 1 O   F HOH 520 ? ? O   F HOH 666 ? ? 2.14 
103 1 O   F HOH 517 ? ? O   F HOH 675 ? ? 2.14 
104 1 OG  D SER 440 ? ? O   D HOH 509 ? ? 2.14 
105 1 O   B ARG 355 ? ? O   B HOH 506 ? ? 2.15 
106 1 OG1 G THR 237 ? ? O   G HOH 504 ? ? 2.15 
107 1 O   B TRP 288 ? ? O   B HOH 507 ? ? 2.15 
108 1 O   B THR 77  ? ? O   B HOH 508 ? ? 2.15 
109 1 OD1 E ASP 360 ? ? O   E HOH 508 ? ? 2.15 
110 1 O   B GLY 332 ? ? O   B HOH 509 ? ? 2.15 
111 1 O   G ARG 249 ? ? O   G HOH 505 ? ? 2.15 
112 1 N   A SER 192 ? ? O   A HOH 507 ? ? 2.15 
113 1 O   F GLY 377 ? ? N   F ALA 379 ? ? 2.15 
114 1 O   C HOH 648 ? ? O   C HOH 650 ? ? 2.15 
115 1 OE2 E GLU 354 ? ? O   E HOH 509 ? ? 2.16 
116 1 N   D ASP 54  ? ? O   D HOH 510 ? ? 2.16 
117 1 O   E PRO 55  ? ? O   E HOH 510 ? ? 2.16 
118 1 O   B HOH 529 ? ? O   B HOH 647 ? ? 2.16 
119 1 OG1 F THR 33  ? ? O   F HOH 514 ? ? 2.16 
120 1 O   G PRO 375 ? ? O   G HOH 506 ? ? 2.16 
121 1 NH1 H ARG 94  ? ? O   H HOH 510 ? ? 2.16 
122 1 OE2 C GLU 245 ? ? O   C HOH 505 ? ? 2.16 
123 1 OG  B SER 29  ? ? O   B HOH 510 ? ? 2.17 
124 1 O   A SER 207 ? ? N   A GLY 284 ? ? 2.17 
125 1 OG  H SER 384 ? ? O   H HOH 511 ? ? 2.17 
126 1 OD1 G ASP 292 ? ? OG  G SER 368 ? ? 2.17 
127 1 O   G ALA 286 ? ? O   G HOH 507 ? ? 2.17 
128 1 ND2 C ASN 137 ? ? O   C HOH 506 ? ? 2.17 
129 1 O   D HOH 576 ? ? O   D HOH 630 ? ? 2.17 
130 1 OE1 D GLU 245 ? ? O   D HOH 511 ? ? 2.17 
131 1 ND1 A HIS 359 ? ? O   A HOH 508 ? ? 2.18 
132 1 O   C HOH 628 ? ? O   C HOH 646 ? ? 2.18 
133 1 O   B HOH 548 ? ? O   C HOH 559 ? ? 2.18 
134 1 NE2 G GLN 87  ? ? O   G HOH 508 ? ? 2.18 
135 1 OD2 D ASP 63  ? ? O   D HOH 512 ? ? 2.18 
136 1 N   B TYR 275 ? ? O   B HOH 511 ? ? 2.18 
137 1 OD2 A ASP 56  ? ? O   A HOH 509 ? ? 2.18 
138 1 OE2 A GLU 338 ? ? O   A HOH 510 ? ? 2.18 
139 1 O   G HOH 632 ? ? O   G HOH 683 ? ? 2.18 
140 1 O   F HOH 687 ? ? O   G HOH 690 ? ? 2.19 
141 1 O   E HOH 632 ? ? O   E HOH 659 ? ? 2.19 
142 1 NZ  C LYS 420 ? ? O   C HOH 507 ? ? 2.19 
143 1 OE2 H GLU 300 ? ? O   H HOH 512 ? ? 2.19 
144 1 O   E ALA 286 ? ? O   E HOH 507 ? ? 2.19 
145 1 O   H HOH 660 ? ? O   H HOH 670 ? ? 2.19 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O   A HOH 648 ? ? 1_555 O   H HOH 678 ? ? 1_554 1.91 
2 1 NZ  A LYS 304 ? ? 1_555 OD2 C ASP 263 ? ? 1_455 1.97 
3 1 O   C HOH 572 ? ? 1_555 O   D HOH 579 ? ? 1_545 2.07 
4 1 O   A HOH 679 ? ? 1_555 O   C HOH 618 ? ? 1_455 2.07 
5 1 O   C HOH 660 ? ? 1_555 O   D HOH 653 ? ? 1_545 2.08 
6 1 O   G HOH 583 ? ? 1_555 O   H HOH 506 ? ? 1_665 2.18 
7 1 O   C HOH 649 ? ? 1_555 O   D HOH 642 ? ? 1_545 2.18 
8 1 OD1 A ASN 220 ? ? 1_555 OG1 H THR 203 ? ? 1_554 2.18 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CG 
_pdbx_validate_rmsd_bond.auth_asym_id_1            E 
_pdbx_validate_rmsd_bond.auth_comp_id_1            ARG 
_pdbx_validate_rmsd_bond.auth_seq_id_1             383 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_2            E 
_pdbx_validate_rmsd_bond.auth_comp_id_2            ARG 
_pdbx_validate_rmsd_bond.auth_seq_id_2             383 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.341 
_pdbx_validate_rmsd_bond.bond_target_value         1.515 
_pdbx_validate_rmsd_bond.bond_deviation            -0.174 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.025 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 CG A ARG 266 ? ? CD A ARG 266 ? ? NE  A ARG 266 ? ? 99.19  111.80 -12.61 2.10 N 
2  1 CD A ARG 266 ? ? NE A ARG 266 ? ? CZ  A ARG 266 ? ? 134.00 123.60 10.40  1.40 N 
3  1 NE A ARG 266 ? ? CZ A ARG 266 ? ? NH1 A ARG 266 ? ? 123.63 120.30 3.33   0.50 N 
4  1 C  B ALA 153 ? ? N  B GLY 154 ? ? CA  B GLY 154 ? ? 109.38 122.30 -12.92 2.10 Y 
5  1 C  B SER 293 ? ? N  B PRO 294 ? ? CD  B PRO 294 ? ? 111.16 128.40 -17.24 2.10 Y 
6  1 C  C SER 293 ? ? N  C PRO 294 ? ? CD  C PRO 294 ? ? 106.14 128.40 -22.26 2.10 Y 
7  1 C  D SER 293 ? ? N  D PRO 294 ? ? CD  D PRO 294 ? ? 98.92  128.40 -29.48 2.10 Y 
8  1 C  E SER 293 ? ? N  E PRO 294 ? ? CD  E PRO 294 ? ? 112.29 128.40 -16.11 2.10 Y 
9  1 CB E ARG 383 ? ? CG E ARG 383 ? ? CD  E ARG 383 ? ? 82.02  111.60 -29.58 2.60 N 
10 1 C  H SER 293 ? ? N  H PRO 294 ? ? CD  H PRO 294 ? ? 102.48 128.40 -25.92 2.10 Y 
11 1 C  H GLY 410 ? ? N  H PRO 411 ? ? CD  H PRO 411 ? ? 100.15 128.40 -28.25 2.10 Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 51  ? ? -123.78 -145.01 
2  1 PRO A 80  ? ? -49.50  154.16  
3  1 SER A 192 ? ? 158.84  -139.74 
4  1 PRO A 205 ? ? -63.98  3.05    
5  1 SER A 207 ? ? -166.18 109.11  
6  1 ALA A 219 ? ? -160.92 101.11  
7  1 GLN A 222 ? ? -103.87 57.65   
8  1 SER A 293 ? ? 49.15   -160.26 
9  1 PRO A 294 ? ? -10.86  96.41   
10 1 ASN A 406 ? ? -161.72 70.44   
11 1 PRO A 411 ? ? -20.97  114.53  
12 1 LEU A 439 ? ? -82.16  41.91   
13 1 SER B 29  ? ? 48.97   24.17   
14 1 PRO B 50  ? ? -71.09  -153.96 
15 1 ASP B 51  ? ? 29.70   -149.76 
16 1 SER B 112 ? ? -68.67  66.89   
17 1 HIS B 196 ? ? 71.01   87.30   
18 1 PHE B 209 ? ? 64.31   69.72   
19 1 ARG B 213 ? ? -81.48  -77.94  
20 1 PRO B 294 ? ? 26.25   110.69  
21 1 ASN B 406 ? ? -162.57 76.22   
22 1 LEU B 409 ? ? -126.98 -55.16  
23 1 ASP C 51  ? ? -97.02  -138.46 
24 1 GLU C 206 ? ? -65.89  45.06   
25 1 GLU C 214 ? ? 69.01   154.08  
26 1 GLN C 222 ? ? 86.17   -1.18   
27 1 ALA C 250 ? ? 74.19   110.43  
28 1 PRO C 294 ? ? 31.17   110.88  
29 1 ASP C 331 ? ? -69.06  1.98    
30 1 ARG C 342 ? ? 173.13  171.40  
31 1 ASN C 406 ? ? -157.44 71.97   
32 1 ARG D 10  ? ? 82.11   78.62   
33 1 ASP D 51  ? ? -111.83 -136.37 
34 1 PHE D 108 ? ? -117.28 76.52   
35 1 GLU D 206 ? ? -41.82  109.14  
36 1 SER D 208 ? ? -60.54  73.31   
37 1 ALA D 219 ? ? -173.91 143.58  
38 1 ALA D 286 ? ? 68.63   89.12   
39 1 PRO D 294 ? ? 32.12   92.62   
40 1 ARG D 342 ? ? 167.90  165.67  
41 1 VAL D 390 ? ? -140.29 19.83   
42 1 ASN D 406 ? ? -160.02 78.05   
43 1 ASP E 68  ? ? -64.62  88.79   
44 1 ASN E 124 ? ? -96.34  48.15   
45 1 SER E 192 ? ? 72.77   -87.99  
46 1 HIS E 196 ? ? 57.17   -85.78  
47 1 PRO E 294 ? ? 17.81   114.92  
48 1 ARG E 342 ? ? 172.73  177.85  
49 1 ASN E 406 ? ? -164.85 72.32   
50 1 PRO E 411 ? ? -18.67  69.04   
51 1 ASN F 8   ? ? -100.39 67.70   
52 1 ASP F 51  ? ? -128.37 -146.15 
53 1 VAL F 53  ? ? -130.34 -69.07  
54 1 ASP F 54  ? ? 119.27  117.14  
55 1 ASN F 143 ? ? 75.28   -1.33   
56 1 ASP F 261 ? ? -141.69 12.18   
57 1 GLU F 276 ? ? -178.04 145.43  
58 1 SER F 293 ? ? 68.91   -111.65 
59 1 ARG F 342 ? ? 176.68  170.57  
60 1 LEU F 378 ? ? -49.10  24.91   
61 1 ALA F 379 ? ? -117.88 -105.02 
62 1 ASP F 380 ? ? 13.82   -65.87  
63 1 ASN F 406 ? ? -154.85 65.00   
64 1 SER G 30  ? ? -132.04 -32.03  
65 1 ASP G 51  ? ? -97.74  -154.01 
66 1 ARG G 191 ? ? -105.65 -61.56  
67 1 GLU G 276 ? ? -124.21 -159.49 
68 1 ARG G 342 ? ? 177.27  179.03  
69 1 ASN G 406 ? ? -160.19 69.49   
70 1 LEU G 409 ? ? -52.09  103.13  
71 1 ASP H 51  ? ? -94.29  -146.09 
72 1 SER H 192 ? ? 68.30   -82.13  
73 1 GLU H 206 ? ? -49.59  -17.86  
74 1 PRO H 294 ? ? 23.83   112.08  
75 1 ARG H 342 ? ? 166.55  172.33  
76 1 ASP H 360 ? ? -98.80  34.24   
77 1 ASN H 406 ? ? -155.17 75.92   
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1  1 MET A 1   ? ? PRO A 2   ? ? -148.63 
2  1 SER A 293 ? ? PRO A 294 ? ? -117.67 
3  1 LEU A 371 ? ? ASN A 372 ? ? -148.54 
4  1 GLY A 410 ? ? PRO A 411 ? ? -136.93 
5  1 SER B 293 ? ? PRO B 294 ? ? -115.52 
6  1 SER C 293 ? ? PRO C 294 ? ? -113.54 
7  1 SER D 293 ? ? PRO D 294 ? ? -116.15 
8  1 SER E 293 ? ? PRO E 294 ? ? -118.30 
9  1 GLY E 410 ? ? PRO E 411 ? ? -145.94 
10 1 LEU F 378 ? ? ALA F 379 ? ? -143.22 
11 1 ALA F 379 ? ? ASP F 380 ? ? 113.53  
12 1 GLY F 410 ? ? PRO F 411 ? ? -132.96 
13 1 ASP G 292 ? ? SER G 293 ? ? -135.14 
14 1 SER G 293 ? ? PRO G 294 ? ? 114.60  
15 1 LEU G 371 ? ? ASN G 372 ? ? -149.93 
16 1 GLY G 410 ? ? PRO G 411 ? ? -135.20 
17 1 SER H 293 ? ? PRO H 294 ? ? -103.43 
18 1 GLY H 410 ? ? PRO H 411 ? ? 124.86  
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    D 
_pdbx_validate_planes.auth_seq_id     264 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.077 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1  1 O ? A HOH 690 ? 6.62 . 
2  1 O ? B HOH 664 ? 6.31 . 
3  1 O ? B HOH 665 ? 7.29 . 
4  1 O ? B HOH 666 ? 7.34 . 
5  1 O ? B HOH 667 ? 7.81 . 
6  1 O ? C HOH 660 ? 7.03 . 
7  1 O ? D HOH 656 ? 6.03 . 
8  1 O ? D HOH 657 ? 6.29 . 
9  1 O ? D HOH 658 ? 6.58 . 
10 1 O ? D HOH 659 ? 6.93 . 
11 1 O ? E HOH 699 ? 5.81 . 
12 1 O ? E HOH 700 ? 6.46 . 
13 1 O ? F HOH 690 ? 6.64 . 
14 1 O ? G HOH 687 ? 6.01 . 
15 1 O ? G HOH 688 ? 6.23 . 
16 1 O ? G HOH 689 ? 6.36 . 
17 1 O ? G HOH 690 ? 6.46 . 
18 1 O ? G HOH 691 ? 6.79 . 
19 1 O ? H HOH 697 ? 8.83 . 
20 1 O ? H HOH 698 ? 9.36 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A ARG 10  ? A ARG 10  
2   1 Y 1 A ALA 11  ? A ALA 11  
3   1 Y 1 A ASP 12  ? A ASP 12  
4   1 Y 1 A TYR 13  ? A TYR 13  
5   1 Y 1 A SER 14  ? A SER 14  
6   1 Y 1 A GLU 15  ? A GLU 15  
7   1 Y 1 A GLN 16  ? A GLN 16  
8   1 Y 1 A VAL 17  ? A VAL 17  
9   1 Y 1 A ARG 18  ? A ARG 18  
10  1 Y 1 A ASP 19  ? A ASP 19  
11  1 Y 1 A TRP 20  ? A TRP 20  
12  1 Y 1 A LEU 21  ? A LEU 21  
13  1 Y 1 A GLY 22  ? A GLY 22  
14  1 Y 1 A ILE 23  ? A ILE 23  
15  1 Y 1 A SER 24  ? A SER 24  
16  1 Y 1 A ASP 25  ? A ASP 25  
17  1 Y 1 A ALA 26  ? A ALA 26  
18  1 Y 1 A THR 27  ? A THR 27  
19  1 Y 1 A ALA 28  ? A ALA 28  
20  1 Y 1 A SER 29  ? A SER 29  
21  1 Y 1 A LEU 278 ? A LEU 278 
22  1 Y 1 A PRO 279 ? A PRO 279 
23  1 Y 1 A GLU 280 ? A GLU 280 
24  1 Y 1 A GLY 281 ? A GLY 281 
25  1 Y 1 A SER 282 ? A SER 282 
26  1 Y 1 A GLY 283 ? A GLY 283 
27  1 Y 1 A LEU 441 ? A LEU 441 
28  1 Y 1 A GLU 442 ? A GLU 442 
29  1 Y 1 A HIS 443 ? A HIS 443 
30  1 Y 1 A HIS 444 ? A HIS 444 
31  1 Y 1 A HIS 445 ? A HIS 445 
32  1 Y 1 A HIS 446 ? A HIS 446 
33  1 Y 1 A HIS 447 ? A HIS 447 
34  1 Y 1 A HIS 448 ? A HIS 448 
35  1 Y 1 B MET 1   ? B MET 1   
36  1 Y 1 B PHE 9   ? B PHE 9   
37  1 Y 1 B ARG 10  ? B ARG 10  
38  1 Y 1 B ALA 11  ? B ALA 11  
39  1 Y 1 B ASP 12  ? B ASP 12  
40  1 Y 1 B TYR 13  ? B TYR 13  
41  1 Y 1 B SER 14  ? B SER 14  
42  1 Y 1 B GLU 15  ? B GLU 15  
43  1 Y 1 B GLN 16  ? B GLN 16  
44  1 Y 1 B VAL 17  ? B VAL 17  
45  1 Y 1 B ARG 18  ? B ARG 18  
46  1 Y 1 B ASP 19  ? B ASP 19  
47  1 Y 1 B TRP 20  ? B TRP 20  
48  1 Y 1 B LEU 21  ? B LEU 21  
49  1 Y 1 B GLY 22  ? B GLY 22  
50  1 Y 1 B ILE 23  ? B ILE 23  
51  1 Y 1 B SER 24  ? B SER 24  
52  1 Y 1 B ASP 25  ? B ASP 25  
53  1 Y 1 B ALA 26  ? B ALA 26  
54  1 Y 1 B GLN 277 ? B GLN 277 
55  1 Y 1 B LEU 278 ? B LEU 278 
56  1 Y 1 B PRO 279 ? B PRO 279 
57  1 Y 1 B GLU 280 ? B GLU 280 
58  1 Y 1 B GLY 281 ? B GLY 281 
59  1 Y 1 B SER 282 ? B SER 282 
60  1 Y 1 B GLY 283 ? B GLY 283 
61  1 Y 1 B GLY 284 ? B GLY 284 
62  1 Y 1 B LEU 441 ? B LEU 441 
63  1 Y 1 B GLU 442 ? B GLU 442 
64  1 Y 1 B HIS 443 ? B HIS 443 
65  1 Y 1 B HIS 444 ? B HIS 444 
66  1 Y 1 B HIS 445 ? B HIS 445 
67  1 Y 1 B HIS 446 ? B HIS 446 
68  1 Y 1 B HIS 447 ? B HIS 447 
69  1 Y 1 B HIS 448 ? B HIS 448 
70  1 Y 1 C PHE 9   ? C PHE 9   
71  1 Y 1 C ARG 10  ? C ARG 10  
72  1 Y 1 C ALA 11  ? C ALA 11  
73  1 Y 1 C ASP 12  ? C ASP 12  
74  1 Y 1 C TYR 13  ? C TYR 13  
75  1 Y 1 C SER 14  ? C SER 14  
76  1 Y 1 C GLU 15  ? C GLU 15  
77  1 Y 1 C GLN 16  ? C GLN 16  
78  1 Y 1 C VAL 17  ? C VAL 17  
79  1 Y 1 C ARG 18  ? C ARG 18  
80  1 Y 1 C ASP 19  ? C ASP 19  
81  1 Y 1 C TRP 20  ? C TRP 20  
82  1 Y 1 C LEU 21  ? C LEU 21  
83  1 Y 1 C GLY 22  ? C GLY 22  
84  1 Y 1 C ILE 23  ? C ILE 23  
85  1 Y 1 C SER 24  ? C SER 24  
86  1 Y 1 C ASP 25  ? C ASP 25  
87  1 Y 1 C ALA 26  ? C ALA 26  
88  1 Y 1 C THR 27  ? C THR 27  
89  1 Y 1 C ALA 28  ? C ALA 28  
90  1 Y 1 C SER 192 ? C SER 192 
91  1 Y 1 C GLY 193 ? C GLY 193 
92  1 Y 1 C GLY 194 ? C GLY 194 
93  1 Y 1 C GLY 195 ? C GLY 195 
94  1 Y 1 C HIS 196 ? C HIS 196 
95  1 Y 1 C GLN 277 ? C GLN 277 
96  1 Y 1 C LEU 278 ? C LEU 278 
97  1 Y 1 C PRO 279 ? C PRO 279 
98  1 Y 1 C GLU 280 ? C GLU 280 
99  1 Y 1 C GLY 281 ? C GLY 281 
100 1 Y 1 C SER 282 ? C SER 282 
101 1 Y 1 C GLY 283 ? C GLY 283 
102 1 Y 1 C LEU 441 ? C LEU 441 
103 1 Y 1 C GLU 442 ? C GLU 442 
104 1 Y 1 C HIS 443 ? C HIS 443 
105 1 Y 1 C HIS 444 ? C HIS 444 
106 1 Y 1 C HIS 445 ? C HIS 445 
107 1 Y 1 C HIS 446 ? C HIS 446 
108 1 Y 1 C HIS 447 ? C HIS 447 
109 1 Y 1 C HIS 448 ? C HIS 448 
110 1 Y 1 D ASP 12  ? D ASP 12  
111 1 Y 1 D TYR 13  ? D TYR 13  
112 1 Y 1 D SER 14  ? D SER 14  
113 1 Y 1 D GLU 15  ? D GLU 15  
114 1 Y 1 D GLN 16  ? D GLN 16  
115 1 Y 1 D VAL 17  ? D VAL 17  
116 1 Y 1 D ARG 18  ? D ARG 18  
117 1 Y 1 D ASP 19  ? D ASP 19  
118 1 Y 1 D TRP 20  ? D TRP 20  
119 1 Y 1 D LEU 21  ? D LEU 21  
120 1 Y 1 D GLY 22  ? D GLY 22  
121 1 Y 1 D ILE 23  ? D ILE 23  
122 1 Y 1 D SER 24  ? D SER 24  
123 1 Y 1 D ASP 25  ? D ASP 25  
124 1 Y 1 D ALA 26  ? D ALA 26  
125 1 Y 1 D THR 27  ? D THR 27  
126 1 Y 1 D ALA 28  ? D ALA 28  
127 1 Y 1 D SER 29  ? D SER 29  
128 1 Y 1 D LEU 278 ? D LEU 278 
129 1 Y 1 D PRO 279 ? D PRO 279 
130 1 Y 1 D GLU 280 ? D GLU 280 
131 1 Y 1 D GLY 281 ? D GLY 281 
132 1 Y 1 D SER 282 ? D SER 282 
133 1 Y 1 D LEU 441 ? D LEU 441 
134 1 Y 1 D GLU 442 ? D GLU 442 
135 1 Y 1 D HIS 443 ? D HIS 443 
136 1 Y 1 D HIS 444 ? D HIS 444 
137 1 Y 1 D HIS 445 ? D HIS 445 
138 1 Y 1 D HIS 446 ? D HIS 446 
139 1 Y 1 D HIS 447 ? D HIS 447 
140 1 Y 1 D HIS 448 ? D HIS 448 
141 1 Y 1 E MET 1   ? E MET 1   
142 1 Y 1 E TYR 13  ? E TYR 13  
143 1 Y 1 E SER 14  ? E SER 14  
144 1 Y 1 E GLU 15  ? E GLU 15  
145 1 Y 1 E GLN 16  ? E GLN 16  
146 1 Y 1 E VAL 17  ? E VAL 17  
147 1 Y 1 E ARG 18  ? E ARG 18  
148 1 Y 1 E ASP 19  ? E ASP 19  
149 1 Y 1 E TRP 20  ? E TRP 20  
150 1 Y 1 E LEU 21  ? E LEU 21  
151 1 Y 1 E GLY 22  ? E GLY 22  
152 1 Y 1 E ILE 23  ? E ILE 23  
153 1 Y 1 E SER 24  ? E SER 24  
154 1 Y 1 E ASP 25  ? E ASP 25  
155 1 Y 1 E ALA 26  ? E ALA 26  
156 1 Y 1 E THR 27  ? E THR 27  
157 1 Y 1 E ALA 28  ? E ALA 28  
158 1 Y 1 E GLN 277 ? E GLN 277 
159 1 Y 1 E LEU 278 ? E LEU 278 
160 1 Y 1 E PRO 279 ? E PRO 279 
161 1 Y 1 E GLU 280 ? E GLU 280 
162 1 Y 1 E GLY 281 ? E GLY 281 
163 1 Y 1 E SER 282 ? E SER 282 
164 1 Y 1 E GLY 283 ? E GLY 283 
165 1 Y 1 E GLY 284 ? E GLY 284 
166 1 Y 1 E LEU 441 ? E LEU 441 
167 1 Y 1 E GLU 442 ? E GLU 442 
168 1 Y 1 E HIS 443 ? E HIS 443 
169 1 Y 1 E HIS 444 ? E HIS 444 
170 1 Y 1 E HIS 445 ? E HIS 445 
171 1 Y 1 E HIS 446 ? E HIS 446 
172 1 Y 1 E HIS 447 ? E HIS 447 
173 1 Y 1 E HIS 448 ? E HIS 448 
174 1 Y 1 F ARG 10  ? F ARG 10  
175 1 Y 1 F ALA 11  ? F ALA 11  
176 1 Y 1 F ASP 12  ? F ASP 12  
177 1 Y 1 F TYR 13  ? F TYR 13  
178 1 Y 1 F SER 14  ? F SER 14  
179 1 Y 1 F GLU 15  ? F GLU 15  
180 1 Y 1 F GLN 16  ? F GLN 16  
181 1 Y 1 F VAL 17  ? F VAL 17  
182 1 Y 1 F ARG 18  ? F ARG 18  
183 1 Y 1 F ASP 19  ? F ASP 19  
184 1 Y 1 F TRP 20  ? F TRP 20  
185 1 Y 1 F LEU 21  ? F LEU 21  
186 1 Y 1 F GLY 22  ? F GLY 22  
187 1 Y 1 F ILE 23  ? F ILE 23  
188 1 Y 1 F SER 24  ? F SER 24  
189 1 Y 1 F ASP 25  ? F ASP 25  
190 1 Y 1 F ALA 26  ? F ALA 26  
191 1 Y 1 F THR 27  ? F THR 27  
192 1 Y 1 F ALA 28  ? F ALA 28  
193 1 Y 1 F SER 29  ? F SER 29  
194 1 Y 1 F SER 30  ? F SER 30  
195 1 Y 1 F LEU 278 ? F LEU 278 
196 1 Y 1 F PRO 279 ? F PRO 279 
197 1 Y 1 F GLU 280 ? F GLU 280 
198 1 Y 1 F GLY 281 ? F GLY 281 
199 1 Y 1 F SER 282 ? F SER 282 
200 1 Y 1 F GLY 283 ? F GLY 283 
201 1 Y 1 F LEU 441 ? F LEU 441 
202 1 Y 1 F GLU 442 ? F GLU 442 
203 1 Y 1 F HIS 443 ? F HIS 443 
204 1 Y 1 F HIS 444 ? F HIS 444 
205 1 Y 1 F HIS 445 ? F HIS 445 
206 1 Y 1 F HIS 446 ? F HIS 446 
207 1 Y 1 F HIS 447 ? F HIS 447 
208 1 Y 1 F HIS 448 ? F HIS 448 
209 1 Y 1 G MET 1   ? G MET 1   
210 1 Y 1 G ASP 12  ? G ASP 12  
211 1 Y 1 G TYR 13  ? G TYR 13  
212 1 Y 1 G SER 14  ? G SER 14  
213 1 Y 1 G GLU 15  ? G GLU 15  
214 1 Y 1 G GLN 16  ? G GLN 16  
215 1 Y 1 G VAL 17  ? G VAL 17  
216 1 Y 1 G ARG 18  ? G ARG 18  
217 1 Y 1 G ASP 19  ? G ASP 19  
218 1 Y 1 G TRP 20  ? G TRP 20  
219 1 Y 1 G LEU 21  ? G LEU 21  
220 1 Y 1 G GLY 22  ? G GLY 22  
221 1 Y 1 G ILE 23  ? G ILE 23  
222 1 Y 1 G SER 24  ? G SER 24  
223 1 Y 1 G ASP 25  ? G ASP 25  
224 1 Y 1 G ALA 26  ? G ALA 26  
225 1 Y 1 G THR 27  ? G THR 27  
226 1 Y 1 G ALA 28  ? G ALA 28  
227 1 Y 1 G LEU 278 ? G LEU 278 
228 1 Y 1 G PRO 279 ? G PRO 279 
229 1 Y 1 G GLU 280 ? G GLU 280 
230 1 Y 1 G GLY 281 ? G GLY 281 
231 1 Y 1 G SER 282 ? G SER 282 
232 1 Y 1 G GLY 283 ? G GLY 283 
233 1 Y 1 G GLY 284 ? G GLY 284 
234 1 Y 1 G LYS 287 ? G LYS 287 
235 1 Y 1 G LEU 441 ? G LEU 441 
236 1 Y 1 G GLU 442 ? G GLU 442 
237 1 Y 1 G HIS 443 ? G HIS 443 
238 1 Y 1 G HIS 444 ? G HIS 444 
239 1 Y 1 G HIS 445 ? G HIS 445 
240 1 Y 1 G HIS 446 ? G HIS 446 
241 1 Y 1 G HIS 447 ? G HIS 447 
242 1 Y 1 G HIS 448 ? G HIS 448 
243 1 Y 1 H MET 1   ? H MET 1   
244 1 Y 1 H ALA 11  ? H ALA 11  
245 1 Y 1 H ASP 12  ? H ASP 12  
246 1 Y 1 H TYR 13  ? H TYR 13  
247 1 Y 1 H SER 14  ? H SER 14  
248 1 Y 1 H GLU 15  ? H GLU 15  
249 1 Y 1 H GLN 16  ? H GLN 16  
250 1 Y 1 H VAL 17  ? H VAL 17  
251 1 Y 1 H ARG 18  ? H ARG 18  
252 1 Y 1 H ASP 19  ? H ASP 19  
253 1 Y 1 H TRP 20  ? H TRP 20  
254 1 Y 1 H LEU 21  ? H LEU 21  
255 1 Y 1 H GLY 22  ? H GLY 22  
256 1 Y 1 H ILE 23  ? H ILE 23  
257 1 Y 1 H SER 24  ? H SER 24  
258 1 Y 1 H ASP 25  ? H ASP 25  
259 1 Y 1 H ALA 26  ? H ALA 26  
260 1 Y 1 H THR 27  ? H THR 27  
261 1 Y 1 H ALA 28  ? H ALA 28  
262 1 Y 1 H LEU 278 ? H LEU 278 
263 1 Y 1 H PRO 279 ? H PRO 279 
264 1 Y 1 H GLU 280 ? H GLU 280 
265 1 Y 1 H GLY 281 ? H GLY 281 
266 1 Y 1 H SER 282 ? H SER 282 
267 1 Y 1 H GLY 283 ? H GLY 283 
268 1 Y 1 H GLY 284 ? H GLY 284 
269 1 Y 1 H LEU 441 ? H LEU 441 
270 1 Y 1 H GLU 442 ? H GLU 442 
271 1 Y 1 H HIS 443 ? H HIS 443 
272 1 Y 1 H HIS 444 ? H HIS 444 
273 1 Y 1 H HIS 445 ? H HIS 445 
274 1 Y 1 H HIS 446 ? H HIS 446 
275 1 Y 1 H HIS 447 ? H HIS 447 
276 1 Y 1 H HIS 448 ? H HIS 448 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           22177072 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.type             'in silico model' 
# 
_atom_sites.entry_id                    8YND 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.011373 
_atom_sites.fract_transf_matrix[1][2]   0.005532 
_atom_sites.fract_transf_matrix[1][3]   0.004181 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011050 
_atom_sites.fract_transf_matrix[2][3]   0.003357 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008118 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . MET A 1 1   ? -16.758 -3.363  22.414  1.00 52.52  ? 1   MET A N   1 
ATOM   2     C CA  . MET A 1 1   ? -16.610 -2.249  21.481  1.00 42.57  ? 1   MET A CA  1 
ATOM   3     C C   . MET A 1 1   ? -15.192 -2.211  20.838  1.00 47.33  ? 1   MET A C   1 
ATOM   4     O O   . MET A 1 1   ? -15.008 -2.745  19.721  1.00 47.66  ? 1   MET A O   1 
ATOM   5     C CB  . MET A 1 1   ? -16.936 -0.919  22.186  1.00 38.45  ? 1   MET A CB  1 
ATOM   6     C CG  . MET A 1 1   ? -18.391 -0.440  22.089  1.00 54.06  ? 1   MET A CG  1 
ATOM   7     S SD  . MET A 1 1   ? -18.586 1.289   22.617  1.00 72.70  ? 1   MET A SD  1 
ATOM   8     C CE  . MET A 1 1   ? -20.127 1.241   23.534  1.00 59.19  ? 1   MET A CE  1 
ATOM   9     N N   . PRO A 1 2   ? -14.192 -1.641  21.529  1.00 38.38  ? 2   PRO A N   1 
ATOM   10    C CA  . PRO A 1 2   ? -13.114 -0.972  20.800  1.00 27.57  ? 2   PRO A CA  1 
ATOM   11    C C   . PRO A 1 2   ? -11.978 -1.891  20.396  1.00 24.93  ? 2   PRO A C   1 
ATOM   12    O O   . PRO A 1 2   ? -11.695 -2.921  21.011  1.00 28.85  ? 2   PRO A O   1 
ATOM   13    C CB  . PRO A 1 2   ? -12.636 0.092   21.802  1.00 30.80  ? 2   PRO A CB  1 
ATOM   14    C CG  . PRO A 1 2   ? -13.288 -0.276  23.160  1.00 30.13  ? 2   PRO A CG  1 
ATOM   15    C CD  . PRO A 1 2   ? -13.882 -1.645  22.971  1.00 29.39  ? 2   PRO A CD  1 
ATOM   16    N N   . LYS A 1 3   ? -11.322 -1.491  19.324  1.00 26.75  ? 3   LYS A N   1 
ATOM   17    C CA  . LYS A 1 3   ? -10.177 -2.211  18.805  1.00 24.09  ? 3   LYS A CA  1 
ATOM   18    C C   . LYS A 1 3   ? -9.060  -1.214  18.575  1.00 23.24  ? 3   LYS A C   1 
ATOM   19    O O   . LYS A 1 3   ? -9.294  -0.007  18.478  1.00 21.69  ? 3   LYS A O   1 
ATOM   20    C CB  . LYS A 1 3   ? -10.505 -2.940  17.493  1.00 23.85  ? 3   LYS A CB  1 
ATOM   21    C CG  . LYS A 1 3   ? -11.173 -2.051  16.449  1.00 23.33  ? 3   LYS A CG  1 
ATOM   22    C CD  . LYS A 1 3   ? -11.357 -2.786  15.111  1.00 24.54  ? 3   LYS A CD  1 
ATOM   23    C CE  . LYS A 1 3   ? -11.811 -1.823  14.008  1.00 23.75  ? 3   LYS A CE  1 
ATOM   24    N NZ  . LYS A 1 3   ? -13.149 -1.214  14.337  1.00 29.17  ? 3   LYS A NZ  1 
ATOM   25    N N   . ILE A 1 4   ? -7.842  -1.743  18.494  1.00 22.93  ? 4   ILE A N   1 
ATOM   26    C CA  . ILE A 1 4   ? -6.651  -0.986  18.145  1.00 22.10  ? 4   ILE A CA  1 
ATOM   27    C C   . ILE A 1 4   ? -6.351  -1.266  16.679  1.00 23.54  ? 4   ILE A C   1 
ATOM   28    O O   . ILE A 1 4   ? -5.986  -2.393  16.306  1.00 23.10  ? 4   ILE A O   1 
ATOM   29    C CB  . ILE A 1 4   ? -5.472  -1.364  19.047  1.00 25.27  ? 4   ILE A CB  1 
ATOM   30    C CG1 . ILE A 1 4   ? -5.761  -0.930  20.476  1.00 27.87  ? 4   ILE A CG1 1 
ATOM   31    C CG2 . ILE A 1 4   ? -4.182  -0.756  18.545  1.00 18.52  ? 4   ILE A CG2 1 
ATOM   32    C CD1 . ILE A 1 4   ? -4.915  -1.700  21.480  1.00 31.08  ? 4   ILE A CD1 1 
ATOM   33    N N   . ILE A 1 5   ? -6.538  -0.251  15.847  1.00 22.98  ? 5   ILE A N   1 
ATOM   34    C CA  . ILE A 1 5   ? -6.257  -0.355  14.421  1.00 21.87  ? 5   ILE A CA  1 
ATOM   35    C C   . ILE A 1 5   ? -4.764  -0.155  14.219  1.00 22.56  ? 5   ILE A C   1 
ATOM   36    O O   . ILE A 1 5   ? -4.203  0.857   14.651  1.00 20.71  ? 5   ILE A O   1 
ATOM   37    C CB  . ILE A 1 5   ? -7.071  0.680   13.620  1.00 20.94  ? 5   ILE A CB  1 
ATOM   38    C CG1 . ILE A 1 5   ? -8.568  0.557   13.924  1.00 21.64  ? 5   ILE A CG1 1 
ATOM   39    C CG2 . ILE A 1 5   ? -6.832  0.498   12.106  1.00 17.97  ? 5   ILE A CG2 1 
ATOM   40    C CD1 . ILE A 1 5   ? -9.400  1.779   13.471  1.00 22.87  ? 5   ILE A CD1 1 
ATOM   41    N N   . LEU A 1 6   ? -4.113  -1.106  13.548  1.00 23.99  ? 6   LEU A N   1 
ATOM   42    C CA  . LEU A 1 6   ? -2.652  -1.183  13.568  1.00 24.07  ? 6   LEU A CA  1 
ATOM   43    C C   . LEU A 1 6   ? -2.127  -1.493  12.167  1.00 26.22  ? 6   LEU A C   1 
ATOM   44    O O   . LEU A 1 6   ? -1.922  -2.659  11.807  1.00 25.25  ? 6   LEU A O   1 
ATOM   45    C CB  . LEU A 1 6   ? -2.219  -2.237  14.588  1.00 24.25  ? 6   LEU A CB  1 
ATOM   46    C CG  . LEU A 1 6   ? -0.840  -2.374  15.222  1.00 23.36  ? 6   LEU A CG  1 
ATOM   47    C CD1 . LEU A 1 6   ? 0.086   -2.929  14.230  1.00 30.60  ? 6   LEU A CD1 1 
ATOM   48    C CD2 . LEU A 1 6   ? -0.334  -1.043  15.781  1.00 19.75  ? 6   LEU A CD2 1 
ATOM   49    N N   . PRO A 1 7   ? -1.925  -0.476  11.337  1.00 28.53  ? 7   PRO A N   1 
ATOM   50    C CA  . PRO A 1 7   ? -1.358  -0.719  9.987   1.00 26.78  ? 7   PRO A CA  1 
ATOM   51    C C   . PRO A 1 7   ? 0.155   -0.926  9.989   1.00 26.18  ? 7   PRO A C   1 
ATOM   52    O O   . PRO A 1 7   ? 0.946   -0.037  9.710   1.00 29.21  ? 7   PRO A O   1 
ATOM   53    C CB  . PRO A 1 7   ? -1.747  0.554   9.227   1.00 22.43  ? 7   PRO A CB  1 
ATOM   54    C CG  . PRO A 1 7   ? -1.842  1.578   10.278  1.00 29.31  ? 7   PRO A CG  1 
ATOM   55    C CD  . PRO A 1 7   ? -2.452  0.893   11.459  1.00 29.10  ? 7   PRO A CD  1 
ATOM   56    N N   . ASN A 1 8   ? 0.569   -2.143  10.310  1.00 28.29  ? 8   ASN A N   1 
ATOM   57    C CA  . ASN A 1 8   ? 1.984   -2.506  10.408  1.00 30.56  ? 8   ASN A CA  1 
ATOM   58    C C   . ASN A 1 8   ? 2.415   -3.168  9.098   1.00 33.60  ? 8   ASN A C   1 
ATOM   59    O O   . ASN A 1 8   ? 2.256   -4.377  8.929   1.00 35.07  ? 8   ASN A O   1 
ATOM   60    C CB  . ASN A 1 8   ? 2.216   -3.436  11.599  1.00 30.32  ? 8   ASN A CB  1 
ATOM   61    C CG  . ASN A 1 8   ? 1.353   -4.704  11.556  1.00 30.10  ? 8   ASN A CG  1 
ATOM   62    O OD1 . ASN A 1 8   ? 0.162   -4.673  11.218  1.00 26.67  ? 8   ASN A OD1 1 
ATOM   63    N ND2 . ASN A 1 8   ? 1.965   -5.828  11.897  1.00 27.34  ? 8   ASN A ND2 1 
ATOM   64    N N   . PHE A 1 9   ? 2.997   -2.379  8.197   1.00 38.46  ? 9   PHE A N   1 
ATOM   65    C CA  . PHE A 1 9   ? 3.259   -2.751  6.793   1.00 38.27  ? 9   PHE A CA  1 
ATOM   66    C C   . PHE A 1 9   ? 1.943   -2.670  6.045   1.00 35.03  ? 9   PHE A C   1 
ATOM   67    O O   . PHE A 1 9   ? 1.487   -1.579  5.699   1.00 43.76  ? 9   PHE A O   1 
ATOM   68    C CB  . PHE A 1 9   ? 3.874   -4.161  6.613   1.00 39.63  ? 9   PHE A CB  1 
ATOM   69    C CG  . PHE A 1 9   ? 5.079   -4.432  7.471   1.00 40.71  ? 9   PHE A CG  1 
ATOM   70    C CD1 . PHE A 1 9   ? 6.121   -3.526  7.538   1.00 45.35  ? 9   PHE A CD1 1 
ATOM   71    C CD2 . PHE A 1 9   ? 5.164   -5.607  8.215   1.00 39.03  ? 9   PHE A CD2 1 
ATOM   72    C CE1 . PHE A 1 9   ? 7.233   -3.783  8.336   1.00 44.97  ? 9   PHE A CE1 1 
ATOM   73    C CE2 . PHE A 1 9   ? 6.275   -5.872  9.010   1.00 45.05  ? 9   PHE A CE2 1 
ATOM   74    C CZ  . PHE A 1 9   ? 7.302   -4.957  9.076   1.00 43.82  ? 9   PHE A CZ  1 
ATOM   75    N N   . SER A 1 30  ? 4.630   15.543  6.517   1.00 50.14  ? 30  SER A N   1 
ATOM   76    C CA  . SER A 1 30  ? 3.207   15.860  6.408   1.00 52.70  ? 30  SER A CA  1 
ATOM   77    C C   . SER A 1 30  ? 2.435   14.793  5.612   1.00 50.70  ? 30  SER A C   1 
ATOM   78    O O   . SER A 1 30  ? 1.241   14.964  5.311   1.00 49.17  ? 30  SER A O   1 
ATOM   79    C CB  . SER A 1 30  ? 3.018   17.245  5.770   1.00 61.58  ? 30  SER A CB  1 
ATOM   80    O OG  . SER A 1 30  ? 1.652   17.509  5.474   1.00 60.38  ? 30  SER A OG  1 
ATOM   81    N N   . THR A 1 31  ? 3.114   13.695  5.281   1.00 45.39  ? 31  THR A N   1 
ATOM   82    C CA  . THR A 1 31  ? 2.466   12.588  4.586   1.00 42.17  ? 31  THR A CA  1 
ATOM   83    C C   . THR A 1 31  ? 1.443   11.898  5.491   1.00 39.53  ? 31  THR A C   1 
ATOM   84    O O   . THR A 1 31  ? 1.655   11.755  6.699   1.00 44.54  ? 31  THR A O   1 
ATOM   85    C CB  . THR A 1 31  ? 3.532   11.604  4.094   1.00 44.36  ? 31  THR A CB  1 
ATOM   86    O OG1 . THR A 1 31  ? 3.588   11.650  2.662   1.00 46.87  ? 31  THR A OG1 1 
ATOM   87    C CG2 . THR A 1 31  ? 3.244   10.182  4.541   1.00 40.84  ? 31  THR A CG2 1 
ATOM   88    N N   . ASP A 1 32  ? 0.308   11.491  4.910   1.00 36.38  ? 32  ASP A N   1 
ATOM   89    C CA  . ASP A 1 32  ? -0.803  10.957  5.701   1.00 33.49  ? 32  ASP A CA  1 
ATOM   90    C C   . ASP A 1 32  ? -1.304  9.638   5.129   1.00 33.43  ? 32  ASP A C   1 
ATOM   91    O O   . ASP A 1 32  ? -2.507  9.367   5.087   1.00 27.51  ? 32  ASP A O   1 
ATOM   92    C CB  . ASP A 1 32  ? -1.935  11.986  5.844   1.00 32.41  ? 32  ASP A CB  1 
ATOM   93    C CG  . ASP A 1 32  ? -2.715  12.249  4.547   1.00 30.22  ? 32  ASP A CG  1 
ATOM   94    O OD1 . ASP A 1 32  ? -2.216  11.976  3.439   1.00 29.23  ? 32  ASP A OD1 1 
ATOM   95    O OD2 . ASP A 1 32  ? -3.857  12.764  4.646   1.00 31.62  ? 32  ASP A OD2 1 
ATOM   96    N N   . THR A 1 33  ? -0.372  8.763   4.754   1.00 37.15  ? 33  THR A N   1 
ATOM   97    C CA  . THR A 1 33  ? -0.729  7.532   4.058   1.00 34.44  ? 33  THR A CA  1 
ATOM   98    C C   . THR A 1 33  ? -1.525  6.571   4.923   1.00 30.63  ? 33  THR A C   1 
ATOM   99    O O   . THR A 1 33  ? -2.256  5.742   4.376   1.00 29.17  ? 33  THR A O   1 
ATOM   100   C CB  . THR A 1 33  ? 0.529   6.847   3.543   1.00 36.42  ? 33  THR A CB  1 
ATOM   101   O OG1 . THR A 1 33  ? 1.375   7.835   2.937   1.00 38.26  ? 33  THR A OG1 1 
ATOM   102   C CG2 . THR A 1 33  ? 0.178   5.774   2.505   1.00 35.62  ? 33  THR A CG2 1 
ATOM   103   N N   . THR A 1 34  ? -1.415  6.660   6.250   1.00 29.05  ? 34  THR A N   1 
ATOM   104   C CA  . THR A 1 34  ? -2.162  5.769   7.122   1.00 24.63  ? 34  THR A CA  1 
ATOM   105   C C   . THR A 1 34  ? -3.474  6.357   7.579   1.00 29.53  ? 34  THR A C   1 
ATOM   106   O O   . THR A 1 34  ? -4.247  5.663   8.253   1.00 29.53  ? 34  THR A O   1 
ATOM   107   C CB  . THR A 1 34  ? -1.358  5.399   8.367   1.00 33.38  ? 34  THR A CB  1 
ATOM   108   O OG1 . THR A 1 34  ? -0.450  6.449   8.691   1.00 34.35  ? 34  THR A OG1 1 
ATOM   109   C CG2 . THR A 1 34  ? -0.611  4.092   8.179   1.00 32.26  ? 34  THR A CG2 1 
ATOM   110   N N   . ALA A 1 35  ? -3.729  7.622   7.260   1.00 27.85  ? 35  ALA A N   1 
ATOM   111   C CA  . ALA A 1 35  ? -4.985  8.229   7.651   1.00 24.28  ? 35  ALA A CA  1 
ATOM   112   C C   . ALA A 1 35  ? -6.155  7.398   7.172   1.00 22.87  ? 35  ALA A C   1 
ATOM   113   O O   . ALA A 1 35  ? -7.191  7.344   7.843   1.00 24.23  ? 35  ALA A O   1 
ATOM   114   C CB  . ALA A 1 35  ? -5.075  9.656   7.086   1.00 26.91  ? 35  ALA A CB  1 
ATOM   115   N N   . ARG A 1 36  ? -6.003  6.740   6.015   1.00 19.82  ? 36  ARG A N   1 
ATOM   116   C CA  . ARG A 1 36  ? -7.126  6.082   5.361   1.00 17.66  ? 36  ARG A CA  1 
ATOM   117   C C   . ARG A 1 36  ? -7.768  5.061   6.263   1.00 20.77  ? 36  ARG A C   1 
ATOM   118   O O   . ARG A 1 36  ? -8.958  4.773   6.119   1.00 17.42  ? 36  ARG A O   1 
ATOM   119   C CB  . ARG A 1 36  ? -6.672  5.399   4.067   1.00 21.28  ? 36  ARG A CB  1 
ATOM   120   C CG  . ARG A 1 36  ? -5.762  4.165   4.319   1.00 19.54  ? 36  ARG A CG  1 
ATOM   121   C CD  . ARG A 1 36  ? -4.757  3.991   3.202   1.00 25.02  ? 36  ARG A CD  1 
ATOM   122   N NE  . ARG A 1 36  ? -5.403  3.868   1.898   1.00 23.10  ? 36  ARG A NE  1 
ATOM   123   C CZ  . ARG A 1 36  ? -5.738  2.709   1.349   1.00 28.26  ? 36  ARG A CZ  1 
ATOM   124   N NH1 . ARG A 1 36  ? -5.480  1.553   1.954   1.00 23.68  ? 36  ARG A NH1 1 
ATOM   125   N NH2 . ARG A 1 36  ? -6.352  2.705   0.168   1.00 26.36  ? 36  ARG A NH2 1 
ATOM   126   N N   . PHE A 1 37  ? -6.994  4.483   7.179   1.00 22.76  ? 37  PHE A N   1 
ATOM   127   C CA  . PHE A 1 37  ? -7.498  3.422   8.024   1.00 21.07  ? 37  PHE A CA  1 
ATOM   128   C C   . PHE A 1 37  ? -8.381  3.944   9.149   1.00 18.69  ? 37  PHE A C   1 
ATOM   129   O O   . PHE A 1 37  ? -9.016  3.149   9.840   1.00 21.56  ? 37  PHE A O   1 
ATOM   130   C CB  . PHE A 1 37  ? -6.307  2.598   8.537   1.00 23.11  ? 37  PHE A CB  1 
ATOM   131   C CG  . PHE A 1 37  ? -5.513  1.980   7.424   1.00 19.54  ? 37  PHE A CG  1 
ATOM   132   C CD1 . PHE A 1 37  ? -6.103  1.062   6.571   1.00 17.40  ? 37  PHE A CD1 1 
ATOM   133   C CD2 . PHE A 1 37  ? -4.206  2.360   7.188   1.00 20.58  ? 37  PHE A CD2 1 
ATOM   134   C CE1 . PHE A 1 37  ? -5.395  0.509   5.521   1.00 21.13  ? 37  PHE A CE1 1 
ATOM   135   C CE2 . PHE A 1 37  ? -3.484  1.811   6.143   1.00 21.63  ? 37  PHE A CE2 1 
ATOM   136   C CZ  . PHE A 1 37  ? -4.077  0.880   5.302   1.00 17.67  ? 37  PHE A CZ  1 
ATOM   137   N N   . LEU A 1 38  ? -8.510  5.258   9.298   1.00 23.65  ? 38  LEU A N   1 
ATOM   138   C CA  . LEU A 1 38  ? -9.531  5.786   10.196  1.00 22.67  ? 38  LEU A CA  1 
ATOM   139   C C   . LEU A 1 38  ? -10.943 5.368   9.799   1.00 21.41  ? 38  LEU A C   1 
ATOM   140   O O   . LEU A 1 38  ? -11.838 5.355   10.657  1.00 22.69  ? 38  LEU A O   1 
ATOM   141   C CB  . LEU A 1 38  ? -9.410  7.308   10.271  1.00 28.52  ? 38  LEU A CB  1 
ATOM   142   C CG  . LEU A 1 38  ? -9.680  7.945   11.644  1.00 31.99  ? 38  LEU A CG  1 
ATOM   143   C CD1 . LEU A 1 38  ? -9.349  6.991   12.805  1.00 35.14  ? 38  LEU A CD1 1 
ATOM   144   C CD2 . LEU A 1 38  ? -8.871  9.214   11.795  1.00 27.80  ? 38  LEU A CD2 1 
ATOM   145   N N   . TRP A 1 39  ? -11.175 4.995   8.534   1.00 18.22  ? 39  TRP A N   1 
ATOM   146   C CA  . TRP A 1 39  ? -12.524 4.596   8.154   1.00 22.00  ? 39  TRP A CA  1 
ATOM   147   C C   . TRP A 1 39  ? -12.923 3.225   8.724   1.00 20.42  ? 39  TRP A C   1 
ATOM   148   O O   . TRP A 1 39  ? -14.097 2.859   8.644   1.00 23.20  ? 39  TRP A O   1 
ATOM   149   C CB  . TRP A 1 39  ? -12.668 4.638   6.621   1.00 22.81  ? 39  TRP A CB  1 
ATOM   150   C CG  . TRP A 1 39  ? -12.638 6.054   6.012   1.00 24.35  ? 39  TRP A CG  1 
ATOM   151   C CD1 . TRP A 1 39  ? -11.530 6.759   5.626   1.00 24.12  ? 39  TRP A CD1 1 
ATOM   152   C CD2 . TRP A 1 39  ? -13.761 6.897   5.714   1.00 23.30  ? 39  TRP A CD2 1 
ATOM   153   N NE1 . TRP A 1 39  ? -11.896 7.984   5.130   1.00 24.90  ? 39  TRP A NE1 1 
ATOM   154   C CE2 . TRP A 1 39  ? -13.257 8.092   5.175   1.00 22.98  ? 39  TRP A CE2 1 
ATOM   155   C CE3 . TRP A 1 39  ? -15.144 6.769   5.883   1.00 27.43  ? 39  TRP A CE3 1 
ATOM   156   C CZ2 . TRP A 1 39  ? -14.085 9.148   4.787   1.00 26.57  ? 39  TRP A CZ2 1 
ATOM   157   C CZ3 . TRP A 1 39  ? -15.965 7.814   5.484   1.00 24.45  ? 39  TRP A CZ3 1 
ATOM   158   C CH2 . TRP A 1 39  ? -15.436 8.985   4.942   1.00 20.44  ? 39  TRP A CH2 1 
ATOM   159   N N   . HIS A 1 40  ? -11.990 2.470   9.309   1.00 22.55  ? 40  HIS A N   1 
ATOM   160   C CA  . HIS A 1 40  ? -12.335 1.297   10.102  1.00 20.89  ? 40  HIS A CA  1 
ATOM   161   C C   . HIS A 1 40  ? -12.905 1.638   11.465  1.00 22.20  ? 40  HIS A C   1 
ATOM   162   O O   . HIS A 1 40  ? -13.420 0.735   12.131  1.00 22.99  ? 40  HIS A O   1 
ATOM   163   C CB  . HIS A 1 40  ? -11.100 0.431   10.352  1.00 25.21  ? 40  HIS A CB  1 
ATOM   164   C CG  . HIS A 1 40  ? -10.702 -0.415  9.181   1.00 21.54  ? 40  HIS A CG  1 
ATOM   165   N ND1 . HIS A 1 40  ? -9.601  -0.134  8.402   1.00 22.31  ? 40  HIS A ND1 1 
ATOM   166   C CD2 . HIS A 1 40  ? -11.256 -1.532  8.661   1.00 23.60  ? 40  HIS A CD2 1 
ATOM   167   C CE1 . HIS A 1 40  ? -9.493  -1.043  7.449   1.00 18.94  ? 40  HIS A CE1 1 
ATOM   168   N NE2 . HIS A 1 40  ? -10.486 -1.900  7.581   1.00 23.33  ? 40  HIS A NE2 1 
ATOM   169   N N   . ALA A 1 41  ? -12.796 2.893   11.912  1.00 21.18  ? 41  ALA A N   1 
ATOM   170   C CA  . ALA A 1 41  ? -12.988 3.206   13.326  1.00 19.00  ? 41  ALA A CA  1 
ATOM   171   C C   . ALA A 1 41  ? -14.457 3.178   13.733  1.00 23.09  ? 41  ALA A C   1 
ATOM   172   O O   . ALA A 1 41  ? -15.329 3.694   13.033  1.00 24.81  ? 41  ALA A O   1 
ATOM   173   C CB  . ALA A 1 41  ? -12.397 4.577   13.649  1.00 24.62  ? 41  ALA A CB  1 
ATOM   174   N N   . GLU A 1 42  ? -14.722 2.532   14.863  1.00 27.36  ? 42  GLU A N   1 
ATOM   175   C CA  . GLU A 1 42  ? -15.970 2.622   15.606  1.00 29.24  ? 42  GLU A CA  1 
ATOM   176   C C   . GLU A 1 42  ? -15.687 3.271   16.954  1.00 32.52  ? 42  GLU A C   1 
ATOM   177   O O   . GLU A 1 42  ? -14.528 3.423   17.351  1.00 29.68  ? 42  GLU A O   1 
ATOM   178   C CB  . GLU A 1 42  ? -16.604 1.248   15.806  1.00 31.02  ? 42  GLU A CB  1 
ATOM   179   C CG  . GLU A 1 42  ? -17.305 0.723   14.581  1.00 38.44  ? 42  GLU A CG  1 
ATOM   180   C CD  . GLU A 1 42  ? -17.028 -0.720  14.394  1.00 42.79  ? 42  GLU A CD  1 
ATOM   181   O OE1 . GLU A 1 42  ? -16.398 -1.300  15.304  1.00 49.95  ? 42  GLU A OE1 1 
ATOM   182   O OE2 . GLU A 1 42  ? -17.439 -1.277  13.352  1.00 52.61  ? 42  GLU A OE2 1 
ATOM   183   N N   . ASP A 1 43  ? -16.766 3.644   17.651  1.00 31.72  ? 43  ASP A N   1 
ATOM   184   C CA  . ASP A 1 43  ? -16.683 4.305   18.955  1.00 28.73  ? 43  ASP A CA  1 
ATOM   185   C C   . ASP A 1 43  ? -15.672 3.636   19.870  1.00 30.17  ? 43  ASP A C   1 
ATOM   186   O O   . ASP A 1 43  ? -15.732 2.425   20.092  1.00 27.39  ? 43  ASP A O   1 
ATOM   187   C CB  . ASP A 1 43  ? -18.050 4.272   19.631  1.00 36.37  ? 43  ASP A CB  1 
ATOM   188   C CG  . ASP A 1 43  ? -18.857 5.507   19.367  1.00 40.47  ? 43  ASP A CG  1 
ATOM   189   O OD1 . ASP A 1 43  ? -18.489 6.261   18.436  1.00 44.45  ? 43  ASP A OD1 1 
ATOM   190   O OD2 . ASP A 1 43  ? -19.860 5.715   20.088  1.00 42.32  ? 43  ASP A OD2 1 
ATOM   191   N N   . GLY A 1 44  ? -14.745 4.439   20.413  1.00 32.54  ? 44  GLY A N   1 
ATOM   192   C CA  . GLY A 1 44  ? -13.748 3.952   21.344  1.00 29.01  ? 44  GLY A CA  1 
ATOM   193   C C   . GLY A 1 44  ? -12.456 3.471   20.717  1.00 27.94  ? 44  GLY A C   1 
ATOM   194   O O   . GLY A 1 44  ? -11.470 3.301   21.439  1.00 28.54  ? 44  GLY A O   1 
ATOM   195   N N   . ASP A 1 45  ? -12.425 3.252   19.403  1.00 25.09  ? 45  ASP A N   1 
ATOM   196   C CA  . ASP A 1 45  ? -11.247 2.698   18.747  1.00 25.35  ? 45  ASP A CA  1 
ATOM   197   C C   . ASP A 1 45  ? -10.053 3.639   18.848  1.00 26.68  ? 45  ASP A C   1 
ATOM   198   O O   . ASP A 1 45  ? -10.186 4.847   19.067  1.00 29.62  ? 45  ASP A O   1 
ATOM   199   C CB  . ASP A 1 45  ? -11.525 2.426   17.271  1.00 23.91  ? 45  ASP A CB  1 
ATOM   200   C CG  . ASP A 1 45  ? -12.416 1.251   17.072  1.00 23.20  ? 45  ASP A CG  1 
ATOM   201   O OD1 . ASP A 1 45  ? -12.764 0.640   18.085  1.00 30.07  ? 45  ASP A OD1 1 
ATOM   202   O OD2 . ASP A 1 45  ? -12.792 0.947   15.927  1.00 24.77  ? 45  ASP A OD2 1 
ATOM   203   N N   . VAL A 1 46  ? -8.876  3.064   18.622  1.00 23.22  ? 46  VAL A N   1 
ATOM   204   C CA  . VAL A 1 46  ? -7.611  3.778   18.524  1.00 23.84  ? 46  VAL A CA  1 
ATOM   205   C C   . VAL A 1 46  ? -7.002  3.480   17.163  1.00 21.84  ? 46  VAL A C   1 
ATOM   206   O O   . VAL A 1 46  ? -6.958  2.322   16.729  1.00 24.82  ? 46  VAL A O   1 
ATOM   207   C CB  . VAL A 1 46  ? -6.627  3.356   19.643  1.00 25.62  ? 46  VAL A CB  1 
ATOM   208   C CG1 . VAL A 1 46  ? -5.289  4.073   19.478  1.00 25.81  ? 46  VAL A CG1 1 
ATOM   209   C CG2 . VAL A 1 46  ? -7.221  3.599   21.018  1.00 28.91  ? 46  VAL A CG2 1 
ATOM   210   N N   . LEU A 1 47  ? -6.510  4.514   16.504  1.00 23.78  ? 47  LEU A N   1 
ATOM   211   C CA  . LEU A 1 47  ? -5.749  4.379   15.269  1.00 21.84  ? 47  LEU A CA  1 
ATOM   212   C C   . LEU A 1 47  ? -4.302  4.731   15.562  1.00 25.64  ? 47  LEU A C   1 
ATOM   213   O O   . LEU A 1 47  ? -4.015  5.833   16.051  1.00 23.49  ? 47  LEU A O   1 
ATOM   214   C CB  . LEU A 1 47  ? -6.294  5.289   14.173  1.00 22.56  ? 47  LEU A CB  1 
ATOM   215   C CG  . LEU A 1 47  ? -5.433  5.225   12.902  1.00 27.12  ? 47  LEU A CG  1 
ATOM   216   C CD1 . LEU A 1 47  ? -5.442  3.803   12.306  1.00 22.84  ? 47  LEU A CD1 1 
ATOM   217   C CD2 . LEU A 1 47  ? -5.889  6.232   11.870  1.00 23.27  ? 47  LEU A CD2 1 
ATOM   218   N N   . VAL A 1 48  ? -3.394  3.805   15.268  1.00 25.92  ? 48  VAL A N   1 
ATOM   219   C CA  . VAL A 1 48  ? -1.956  4.059   15.366  1.00 30.22  ? 48  VAL A CA  1 
ATOM   220   C C   . VAL A 1 48  ? -1.441  4.415   13.980  1.00 27.04  ? 48  VAL A C   1 
ATOM   221   O O   . VAL A 1 48  ? -1.651  3.661   13.024  1.00 32.61  ? 48  VAL A O   1 
ATOM   222   C CB  . VAL A 1 48  ? -1.204  2.839   15.926  1.00 25.09  ? 48  VAL A CB  1 
ATOM   223   C CG1 . VAL A 1 48  ? 0.290   3.159   16.103  1.00 27.32  ? 48  VAL A CG1 1 
ATOM   224   C CG2 . VAL A 1 48  ? -1.836  2.385   17.233  1.00 25.50  ? 48  VAL A CG2 1 
ATOM   225   N N   . ILE A 1 49  ? -0.780  5.564   13.860  1.00 33.37  ? 49  ILE A N   1 
ATOM   226   C CA  . ILE A 1 49  ? -0.206  5.975   12.579  1.00 31.83  ? 49  ILE A CA  1 
ATOM   227   C C   . ILE A 1 49  ? 1.282   6.296   12.703  1.00 32.67  ? 49  ILE A C   1 
ATOM   228   O O   . ILE A 1 49  ? 1.718   6.934   13.671  1.00 36.95  ? 49  ILE A O   1 
ATOM   229   C CB  . ILE A 1 49  ? -0.970  7.167   11.984  1.00 32.84  ? 49  ILE A CB  1 
ATOM   230   C CG1 . ILE A 1 49  ? -0.777  8.428   12.810  1.00 36.03  ? 49  ILE A CG1 1 
ATOM   231   C CG2 . ILE A 1 49  ? -2.428  6.874   11.894  1.00 33.96  ? 49  ILE A CG2 1 
ATOM   232   C CD1 . ILE A 1 49  ? -1.383  9.645   12.129  1.00 41.95  ? 49  ILE A CD1 1 
ATOM   233   N N   . PRO A 1 50  ? 2.100   5.870   11.742  1.00 32.69  ? 50  PRO A N   1 
ATOM   234   C CA  . PRO A 1 50  ? 3.531   6.213   11.771  1.00 37.53  ? 50  PRO A CA  1 
ATOM   235   C C   . PRO A 1 50  ? 3.837   7.573   11.180  1.00 37.57  ? 50  PRO A C   1 
ATOM   236   O O   . PRO A 1 50  ? 4.987   8.035   11.250  1.00 34.03  ? 50  PRO A O   1 
ATOM   237   C CB  . PRO A 1 50  ? 4.163   5.102   10.928  1.00 31.64  ? 50  PRO A CB  1 
ATOM   238   C CG  . PRO A 1 50  ? 3.094   4.735   9.964   1.00 33.41  ? 50  PRO A CG  1 
ATOM   239   C CD  . PRO A 1 50  ? 1.778   4.908   10.677  1.00 35.39  ? 50  PRO A CD  1 
ATOM   240   N N   . ASP A 1 51  ? 2.844   8.224   10.601  1.00 34.05  ? 51  ASP A N   1 
ATOM   241   C CA  . ASP A 1 51  ? 3.058   9.521   9.994   1.00 39.81  ? 51  ASP A CA  1 
ATOM   242   C C   . ASP A 1 51  ? 2.093   10.507  10.631  1.00 43.37  ? 51  ASP A C   1 
ATOM   243   O O   . ASP A 1 51  ? 1.788   10.394  11.823  1.00 40.20  ? 51  ASP A O   1 
ATOM   244   C CB  . ASP A 1 51  ? 2.870   9.426   8.477   1.00 38.66  ? 51  ASP A CB  1 
ATOM   245   C CG  . ASP A 1 51  ? 1.736   8.512   8.100   1.00 37.90  ? 51  ASP A CG  1 
ATOM   246   O OD1 . ASP A 1 51  ? 0.719   8.488   8.832   1.00 34.90  ? 51  ASP A OD1 1 
ATOM   247   O OD2 . ASP A 1 51  ? 1.872   7.779   7.100   1.00 43.57  ? 51  ASP A OD2 1 
ATOM   248   N N   . THR A 1 52  ? 1.597   11.462  9.854   1.00 44.09  ? 52  THR A N   1 
ATOM   249   C CA  . THR A 1 52  ? 0.720   12.490  10.380  1.00 41.58  ? 52  THR A CA  1 
ATOM   250   C C   . THR A 1 52  ? -0.666  12.349  9.779   1.00 45.27  ? 52  THR A C   1 
ATOM   251   O O   . THR A 1 52  ? -0.858  11.662  8.772   1.00 42.74  ? 52  THR A O   1 
ATOM   252   C CB  . THR A 1 52  ? 1.258   13.888  10.081  1.00 46.50  ? 52  THR A CB  1 
ATOM   253   O OG1 . THR A 1 52  ? 0.677   14.825  11.000  1.00 54.38  ? 52  THR A OG1 1 
ATOM   254   C CG2 . THR A 1 52  ? 0.895   14.289  8.661   1.00 46.21  ? 52  THR A CG2 1 
ATOM   255   N N   . VAL A 1 53  ? -1.630  13.007  10.428  1.00 39.78  ? 53  VAL A N   1 
ATOM   256   C CA  . VAL A 1 53  ? -2.998  13.128  9.944   1.00 36.51  ? 53  VAL A CA  1 
ATOM   257   C C   . VAL A 1 53  ? -3.413  14.592  10.029  1.00 37.53  ? 53  VAL A C   1 
ATOM   258   O O   . VAL A 1 53  ? -2.977  15.330  10.917  1.00 37.32  ? 53  VAL A O   1 
ATOM   259   C CB  . VAL A 1 53  ? -3.960  12.229  10.751  1.00 35.89  ? 53  VAL A CB  1 
ATOM   260   C CG1 . VAL A 1 53  ? -4.076  12.721  12.167  1.00 41.09  ? 53  VAL A CG1 1 
ATOM   261   C CG2 . VAL A 1 53  ? -5.326  12.188  10.105  1.00 34.02  ? 53  VAL A CG2 1 
ATOM   262   N N   . ASP A 1 54  ? -4.235  15.026  9.083   1.00 38.68  ? 54  ASP A N   1 
ATOM   263   C CA  . ASP A 1 54  ? -4.821  16.362  9.166   1.00 30.59  ? 54  ASP A CA  1 
ATOM   264   C C   . ASP A 1 54  ? -5.744  16.416  10.371  1.00 29.51  ? 54  ASP A C   1 
ATOM   265   O O   . ASP A 1 54  ? -6.661  15.597  10.468  1.00 35.82  ? 54  ASP A O   1 
ATOM   266   C CB  . ASP A 1 54  ? -5.583  16.679  7.885   1.00 39.86  ? 54  ASP A CB  1 
ATOM   267   C CG  . ASP A 1 54  ? -6.148  18.095  7.859   1.00 38.88  ? 54  ASP A CG  1 
ATOM   268   O OD1 . ASP A 1 54  ? -6.746  18.553  8.868   1.00 31.37  ? 54  ASP A OD1 1 
ATOM   269   O OD2 . ASP A 1 54  ? -5.992  18.747  6.797   1.00 41.71  ? 54  ASP A OD2 1 
ATOM   270   N N   . PRO A 1 55  ? -5.565  17.355  11.301  1.00 34.49  ? 55  PRO A N   1 
ATOM   271   C CA  . PRO A 1 55  ? -6.300  17.251  12.579  1.00 38.17  ? 55  PRO A CA  1 
ATOM   272   C C   . PRO A 1 55  ? -7.816  17.381  12.431  1.00 31.43  ? 55  PRO A C   1 
ATOM   273   O O   . PRO A 1 55  ? -8.542  16.933  13.325  1.00 36.16  ? 55  PRO A O   1 
ATOM   274   C CB  . PRO A 1 55  ? -5.708  18.385  13.432  1.00 40.76  ? 55  PRO A CB  1 
ATOM   275   C CG  . PRO A 1 55  ? -4.537  18.941  12.637  1.00 41.24  ? 55  PRO A CG  1 
ATOM   276   C CD  . PRO A 1 55  ? -4.786  18.598  11.203  1.00 36.89  ? 55  PRO A CD  1 
ATOM   277   N N   . ASP A 1 56  ? -8.314  17.947  11.328  1.00 31.75  ? 56  ASP A N   1 
ATOM   278   C CA  . ASP A 1 56  ? -9.743  17.894  11.017  1.00 30.72  ? 56  ASP A CA  1 
ATOM   279   C C   . ASP A 1 56  ? -10.179 16.546  10.465  1.00 33.93  ? 56  ASP A C   1 
ATOM   280   O O   . ASP A 1 56  ? -11.378 16.249  10.490  1.00 36.07  ? 56  ASP A O   1 
ATOM   281   C CB  . ASP A 1 56  ? -10.120 18.956  9.978   1.00 32.39  ? 56  ASP A CB  1 
ATOM   282   C CG  . ASP A 1 56  ? -10.031 20.366  10.509  1.00 36.63  ? 56  ASP A CG  1 
ATOM   283   O OD1 . ASP A 1 56  ? -11.011 20.829  11.107  1.00 39.95  ? 56  ASP A OD1 1 
ATOM   284   O OD2 . ASP A 1 56  ? -8.987  21.023  10.302  1.00 41.86  ? 56  ASP A OD2 1 
ATOM   285   N N   . PHE A 1 57  ? -9.244  15.737  9.940   1.00 34.09  ? 57  PHE A N   1 
ATOM   286   C CA  . PHE A 1 57  ? -9.619  14.482  9.281   1.00 29.58  ? 57  PHE A CA  1 
ATOM   287   C C   . PHE A 1 57  ? -10.433 13.559  10.166  1.00 27.84  ? 57  PHE A C   1 
ATOM   288   O O   . PHE A 1 57  ? -11.441 13.012  9.683   1.00 28.20  ? 57  PHE A O   1 
ATOM   289   C CB  . PHE A 1 57  ? -8.368  13.757  8.766   1.00 24.91  ? 57  PHE A CB  1 
ATOM   290   C CG  . PHE A 1 57  ? -8.659  12.546  7.927   1.00 27.69  ? 57  PHE A CG  1 
ATOM   291   C CD1 . PHE A 1 57  ? -9.442  12.647  6.789   1.00 24.43  ? 57  PHE A CD1 1 
ATOM   292   C CD2 . PHE A 1 57  ? -8.120  11.309  8.256   1.00 28.35  ? 57  PHE A CD2 1 
ATOM   293   C CE1 . PHE A 1 57  ? -9.708  11.551  5.999   1.00 26.15  ? 57  PHE A CE1 1 
ATOM   294   C CE2 . PHE A 1 57  ? -8.378  10.195  7.473   1.00 30.38  ? 57  PHE A CE2 1 
ATOM   295   C CZ  . PHE A 1 57  ? -9.172  10.318  6.326   1.00 31.71  ? 57  PHE A CZ  1 
ATOM   296   N N   . PRO A 1 58  ? -10.069 13.312  11.430  1.00 30.83  ? 58  PRO A N   1 
ATOM   297   C CA  . PRO A 1 58  ? -10.860 12.346  12.205  1.00 27.10  ? 58  PRO A CA  1 
ATOM   298   C C   . PRO A 1 58  ? -12.283 12.814  12.420  1.00 26.21  ? 58  PRO A C   1 
ATOM   299   O O   . PRO A 1 58  ? -13.213 11.999  12.374  1.00 26.85  ? 58  PRO A O   1 
ATOM   300   C CB  . PRO A 1 58  ? -10.086 12.227  13.527  1.00 26.59  ? 58  PRO A CB  1 
ATOM   301   C CG  . PRO A 1 58  ? -8.717  12.778  13.242  1.00 26.22  ? 58  PRO A CG  1 
ATOM   302   C CD  . PRO A 1 58  ? -8.910  13.818  12.196  1.00 29.81  ? 58  PRO A CD  1 
ATOM   303   N N   . GLY A 1 59  ? -12.478 14.117  12.632  1.00 30.43  ? 59  GLY A N   1 
ATOM   304   C CA  . GLY A 1 59  ? -13.822 14.635  12.829  1.00 24.29  ? 59  GLY A CA  1 
ATOM   305   C C   . GLY A 1 59  ? -14.672 14.525  11.581  1.00 27.08  ? 59  GLY A C   1 
ATOM   306   O O   . GLY A 1 59  ? -15.875 14.270  11.660  1.00 27.38  ? 59  GLY A O   1 
ATOM   307   N N   . TYR A 1 60  ? -14.058 14.723  10.413  1.00 24.50  ? 60  TYR A N   1 
ATOM   308   C CA  . TYR A 1 60  ? -14.781 14.596  9.155   1.00 27.92  ? 60  TYR A CA  1 
ATOM   309   C C   . TYR A 1 60  ? -15.170 13.151  8.877   1.00 29.58  ? 60  TYR A C   1 
ATOM   310   O O   . TYR A 1 60  ? -16.207 12.888  8.246   1.00 25.75  ? 60  TYR A O   1 
ATOM   311   C CB  . TYR A 1 60  ? -13.919 15.145  8.020   1.00 25.33  ? 60  TYR A CB  1 
ATOM   312   C CG  . TYR A 1 60  ? -14.190 14.533  6.665   1.00 25.56  ? 60  TYR A CG  1 
ATOM   313   C CD1 . TYR A 1 60  ? -15.217 15.014  5.860   1.00 26.01  ? 60  TYR A CD1 1 
ATOM   314   C CD2 . TYR A 1 60  ? -13.416 13.480  6.186   1.00 26.36  ? 60  TYR A CD2 1 
ATOM   315   C CE1 . TYR A 1 60  ? -15.471 14.478  4.629   1.00 23.65  ? 60  TYR A CE1 1 
ATOM   316   C CE2 . TYR A 1 60  ? -13.670 12.939  4.941   1.00 28.07  ? 60  TYR A CE2 1 
ATOM   317   C CZ  . TYR A 1 60  ? -14.706 13.444  4.163   1.00 23.33  ? 60  TYR A CZ  1 
ATOM   318   O OH  . TYR A 1 60  ? -14.978 12.918  2.907   1.00 26.17  ? 60  TYR A OH  1 
ATOM   319   N N   . VAL A 1 61  ? -14.336 12.204  9.309   1.00 28.51  ? 61  VAL A N   1 
ATOM   320   C CA  . VAL A 1 61  ? -14.640 10.796  9.084   1.00 26.43  ? 61  VAL A CA  1 
ATOM   321   C C   . VAL A 1 61  ? -15.766 10.354  10.007  1.00 26.87  ? 61  VAL A C   1 
ATOM   322   O O   . VAL A 1 61  ? -16.636 9.561   9.621   1.00 25.83  ? 61  VAL A O   1 
ATOM   323   C CB  . VAL A 1 61  ? -13.365 9.955   9.291   1.00 23.67  ? 61  VAL A CB  1 
ATOM   324   C CG1 . VAL A 1 61  ? -13.710 8.481   9.476   1.00 22.76  ? 61  VAL A CG1 1 
ATOM   325   C CG2 . VAL A 1 61  ? -12.397 10.164  8.128   1.00 21.03  ? 61  VAL A CG2 1 
ATOM   326   N N   . ALA A 1 62  ? -15.748 10.844  11.249  1.00 24.62  ? 62  ALA A N   1 
ATOM   327   C CA  . ALA A 1 62  ? -16.803 10.543  12.211  1.00 25.28  ? 62  ALA A CA  1 
ATOM   328   C C   . ALA A 1 62  ? -18.141 11.124  11.772  1.00 25.20  ? 62  ALA A C   1 
ATOM   329   O O   . ALA A 1 62  ? -19.187 10.487  11.941  1.00 29.01  ? 62  ALA A O   1 
ATOM   330   C CB  . ALA A 1 62  ? -16.412 11.097  13.581  1.00 26.68  ? 62  ALA A CB  1 
ATOM   331   N N   . ASP A 1 63  ? -18.122 12.352  11.247  1.00 24.69  ? 63  ASP A N   1 
ATOM   332   C CA  . ASP A 1 63  ? -19.322 12.967  10.679  1.00 31.31  ? 63  ASP A CA  1 
ATOM   333   C C   . ASP A 1 63  ? -19.881 12.130  9.542   1.00 28.97  ? 63  ASP A C   1 
ATOM   334   O O   . ASP A 1 63  ? -21.099 11.960  9.424   1.00 36.26  ? 63  ASP A O   1 
ATOM   335   C CB  . ASP A 1 63  ? -19.011 14.375  10.153  1.00 31.28  ? 63  ASP A CB  1 
ATOM   336   C CG  . ASP A 1 63  ? -18.777 15.370  11.244  1.00 30.78  ? 63  ASP A CG  1 
ATOM   337   O OD1 . ASP A 1 63  ? -19.170 15.086  12.389  1.00 32.83  ? 63  ASP A OD1 1 
ATOM   338   O OD2 . ASP A 1 63  ? -18.173 16.420  10.954  1.00 33.16  ? 63  ASP A OD2 1 
ATOM   339   N N   . THR A 1 64  ? -19.007 11.653  8.652   1.00 25.52  ? 64  THR A N   1 
ATOM   340   C CA  . THR A 1 64  ? -19.493 10.930  7.483   1.00 29.34  ? 64  THR A CA  1 
ATOM   341   C C   . THR A 1 64  ? -20.036 9.558   7.849   1.00 28.62  ? 64  THR A C   1 
ATOM   342   O O   . THR A 1 64  ? -20.974 9.083   7.203   1.00 30.63  ? 64  THR A O   1 
ATOM   343   C CB  . THR A 1 64  ? -18.386 10.773  6.448   1.00 23.60  ? 64  THR A CB  1 
ATOM   344   O OG1 . THR A 1 64  ? -17.730 12.029  6.262   1.00 27.49  ? 64  THR A OG1 1 
ATOM   345   C CG2 . THR A 1 64  ? -18.970 10.271  5.127   1.00 20.57  ? 64  THR A CG2 1 
ATOM   346   N N   . LEU A 1 65  ? -19.459 8.912   8.869   1.00 28.47  ? 65  LEU A N   1 
ATOM   347   C CA  . LEU A 1 65  ? -19.838 7.565   9.288   1.00 25.31  ? 65  LEU A CA  1 
ATOM   348   C C   . LEU A 1 65  ? -20.911 7.544   10.373  1.00 34.19  ? 65  LEU A C   1 
ATOM   349   O O   . LEU A 1 65  ? -21.515 6.490   10.602  1.00 33.68  ? 65  LEU A O   1 
ATOM   350   C CB  . LEU A 1 65  ? -18.607 6.820   9.810   1.00 30.76  ? 65  LEU A CB  1 
ATOM   351   C CG  . LEU A 1 65  ? -17.574 6.363   8.779   1.00 32.17  ? 65  LEU A CG  1 
ATOM   352   C CD1 . LEU A 1 65  ? -16.292 5.916   9.472   1.00 30.13  ? 65  LEU A CD1 1 
ATOM   353   C CD2 . LEU A 1 65  ? -18.163 5.238   7.908   1.00 27.67  ? 65  LEU A CD2 1 
ATOM   354   N N   . GLY A 1 66  ? -21.152 8.668   11.056  1.00 33.66  ? 66  GLY A N   1 
ATOM   355   C CA  . GLY A 1 66  ? -22.145 8.705   12.114  1.00 32.28  ? 66  GLY A CA  1 
ATOM   356   C C   . GLY A 1 66  ? -21.679 8.154   13.446  1.00 35.59  ? 66  GLY A C   1 
ATOM   357   O O   . GLY A 1 66  ? -22.489 7.606   14.193  1.00 35.12  ? 66  GLY A O   1 
ATOM   358   N N   . ILE A 1 67  ? -20.392 8.271   13.768  1.00 29.15  ? 67  ILE A N   1 
ATOM   359   C CA  . ILE A 1 67  ? -19.878 7.830   15.055  1.00 33.40  ? 67  ILE A CA  1 
ATOM   360   C C   . ILE A 1 67  ? -19.380 9.054   15.821  1.00 36.09  ? 67  ILE A C   1 
ATOM   361   O O   . ILE A 1 67  ? -19.251 10.150  15.280  1.00 38.39  ? 67  ILE A O   1 
ATOM   362   C CB  . ILE A 1 67  ? -18.759 6.765   14.928  1.00 32.77  ? 67  ILE A CB  1 
ATOM   363   C CG1 . ILE A 1 67  ? -17.560 7.326   14.161  1.00 31.74  ? 67  ILE A CG1 1 
ATOM   364   C CG2 . ILE A 1 67  ? -19.276 5.494   14.268  1.00 30.41  ? 67  ILE A CG2 1 
ATOM   365   C CD1 . ILE A 1 67  ? -16.282 6.526   14.353  1.00 30.82  ? 67  ILE A CD1 1 
ATOM   366   N N   . ASP A 1 68  ? -19.099 8.844   17.099  1.00 36.18  ? 68  ASP A N   1 
ATOM   367   C CA  . ASP A 1 68  ? -18.667 9.911   17.989  1.00 36.98  ? 68  ASP A CA  1 
ATOM   368   C C   . ASP A 1 68  ? -17.157 10.068  17.842  1.00 38.98  ? 68  ASP A C   1 
ATOM   369   O O   . ASP A 1 68  ? -16.389 9.205   18.275  1.00 40.50  ? 68  ASP A O   1 
ATOM   370   C CB  . ASP A 1 68  ? -19.094 9.566   19.415  1.00 36.85  ? 68  ASP A CB  1 
ATOM   371   C CG  . ASP A 1 68  ? -18.491 10.471  20.469  1.00 40.04  ? 68  ASP A CG  1 
ATOM   372   O OD1 . ASP A 1 68  ? -17.750 11.434  20.151  1.00 33.98  ? 68  ASP A OD1 1 
ATOM   373   O OD2 . ASP A 1 68  ? -18.780 10.196  21.654  1.00 44.96  ? 68  ASP A OD2 1 
ATOM   374   N N   . GLY A 1 69  ? -16.729 11.173  17.234  1.00 39.30  ? 69  GLY A N   1 
ATOM   375   C CA  . GLY A 1 69  ? -15.309 11.381  17.004  1.00 36.44  ? 69  GLY A CA  1 
ATOM   376   C C   . GLY A 1 69  ? -14.515 11.653  18.265  1.00 44.48  ? 69  GLY A C   1 
ATOM   377   O O   . GLY A 1 69  ? -13.310 11.386  18.307  1.00 44.49  ? 69  GLY A O   1 
ATOM   378   N N   . THR A 1 70  ? -15.165 12.188  19.306  1.00 41.02  ? 70  THR A N   1 
ATOM   379   C CA  . THR A 1 70  ? -14.460 12.446  20.560  1.00 42.14  ? 70  THR A CA  1 
ATOM   380   C C   . THR A 1 70  ? -14.068 11.165  21.274  1.00 40.25  ? 70  THR A C   1 
ATOM   381   O O   . THR A 1 70  ? -13.221 11.209  22.173  1.00 44.76  ? 70  THR A O   1 
ATOM   382   C CB  . THR A 1 70  ? -15.314 13.288  21.511  1.00 42.22  ? 70  THR A CB  1 
ATOM   383   O OG1 . THR A 1 70  ? -16.427 12.501  21.969  1.00 42.47  ? 70  THR A OG1 1 
ATOM   384   C CG2 . THR A 1 70  ? -15.821 14.546  20.818  1.00 36.00  ? 70  THR A CG2 1 
ATOM   385   N N   . SER A 1 71  ? -14.684 10.041  20.915  1.00 40.44  ? 71  SER A N   1 
ATOM   386   C CA  . SER A 1 71  ? -14.371 8.734   21.475  1.00 36.76  ? 71  SER A CA  1 
ATOM   387   C C   . SER A 1 71  ? -13.399 7.947   20.605  1.00 38.27  ? 71  SER A C   1 
ATOM   388   O O   . SER A 1 71  ? -13.161 6.767   20.871  1.00 36.38  ? 71  SER A O   1 
ATOM   389   C CB  . SER A 1 71  ? -15.654 7.923   21.673  1.00 35.19  ? 71  SER A CB  1 
ATOM   390   O OG  . SER A 1 71  ? -16.140 7.442   20.430  1.00 27.81  ? 71  SER A OG  1 
ATOM   391   N N   . VAL A 1 72  ? -12.869 8.559   19.552  1.00 36.95  ? 72  VAL A N   1 
ATOM   392   C CA  . VAL A 1 72  ? -11.884 7.941   18.679  1.00 35.81  ? 72  VAL A CA  1 
ATOM   393   C C   . VAL A 1 72  ? -10.545 8.610   18.933  1.00 36.44  ? 72  VAL A C   1 
ATOM   394   O O   . VAL A 1 72  ? -10.457 9.843   18.933  1.00 30.27  ? 72  VAL A O   1 
ATOM   395   C CB  . VAL A 1 72  ? -12.280 8.076   17.201  1.00 38.39  ? 72  VAL A CB  1 
ATOM   396   C CG1 . VAL A 1 72  ? -11.177 7.509   16.324  1.00 35.44  ? 72  VAL A CG1 1 
ATOM   397   C CG2 . VAL A 1 72  ? -13.606 7.371   16.936  1.00 35.29  ? 72  VAL A CG2 1 
ATOM   398   N N   . HIS A 1 73  ? -9.501  7.807   19.122  1.00 35.70  ? 73  HIS A N   1 
ATOM   399   C CA  . HIS A 1 73  ? -8.180  8.328   19.431  1.00 33.11  ? 73  HIS A CA  1 
ATOM   400   C C   . HIS A 1 73  ? -7.166  7.954   18.354  1.00 33.79  ? 73  HIS A C   1 
ATOM   401   O O   . HIS A 1 73  ? -7.229  6.878   17.753  1.00 27.82  ? 73  HIS A O   1 
ATOM   402   C CB  . HIS A 1 73  ? -7.703  7.813   20.783  1.00 38.52  ? 73  HIS A CB  1 
ATOM   403   C CG  . HIS A 1 73  ? -8.706  7.984   21.883  1.00 41.84  ? 73  HIS A CG  1 
ATOM   404   N ND1 . HIS A 1 73  ? -9.095  9.220   22.353  1.00 39.84  ? 73  HIS A ND1 1 
ATOM   405   C CD2 . HIS A 1 73  ? -9.408  7.071   22.600  1.00 42.74  ? 73  HIS A CD2 1 
ATOM   406   C CE1 . HIS A 1 73  ? -9.985  9.063   23.317  1.00 44.41  ? 73  HIS A CE1 1 
ATOM   407   N NE2 . HIS A 1 73  ? -10.193 7.769   23.488  1.00 45.74  ? 73  HIS A NE2 1 
ATOM   408   N N   . VAL A 1 74  ? -6.224  8.864   18.128  1.00 30.31  ? 74  VAL A N   1 
ATOM   409   C CA  . VAL A 1 74  ? -5.090  8.672   17.232  1.00 29.60  ? 74  VAL A CA  1 
ATOM   410   C C   . VAL A 1 74  ? -3.828  8.687   18.088  1.00 33.72  ? 74  VAL A C   1 
ATOM   411   O O   . VAL A 1 74  ? -3.587  9.659   18.816  1.00 32.94  ? 74  VAL A O   1 
ATOM   412   C CB  . VAL A 1 74  ? -5.020  9.775   16.160  1.00 35.27  ? 74  VAL A CB  1 
ATOM   413   C CG1 . VAL A 1 74  ? -3.736  9.658   15.351  1.00 35.19  ? 74  VAL A CG1 1 
ATOM   414   C CG2 . VAL A 1 74  ? -6.251  9.749   15.253  1.00 30.64  ? 74  VAL A CG2 1 
ATOM   415   N N   . GLU A 1 75  ? -3.035  7.619   18.013  1.00 28.00  ? 75  GLU A N   1 
ATOM   416   C CA  . GLU A 1 75  ? -1.741  7.543   18.687  1.00 29.64  ? 75  GLU A CA  1 
ATOM   417   C C   . GLU A 1 75  ? -0.637  7.621   17.639  1.00 36.61  ? 75  GLU A C   1 
ATOM   418   O O   . GLU A 1 75  ? -0.503  6.715   16.803  1.00 28.95  ? 75  GLU A O   1 
ATOM   419   C CB  . GLU A 1 75  ? -1.594  6.252   19.498  1.00 31.95  ? 75  GLU A CB  1 
ATOM   420   C CG  . GLU A 1 75  ? -2.496  6.134   20.735  1.00 37.38  ? 75  GLU A CG  1 
ATOM   421   C CD  . GLU A 1 75  ? -2.175  7.157   21.826  1.00 41.02  ? 75  GLU A CD  1 
ATOM   422   O OE1 . GLU A 1 75  ? -1.055  7.706   21.836  1.00 41.56  ? 75  GLU A OE1 1 
ATOM   423   O OE2 . GLU A 1 75  ? -3.045  7.402   22.690  1.00 41.12  ? 75  GLU A OE2 1 
ATOM   424   N N   . ARG A 1 76  ? 0.154   8.693   17.690  1.00 37.61  ? 76  ARG A N   1 
ATOM   425   C CA  . ARG A 1 76  ? 1.250   8.905   16.750  1.00 39.12  ? 76  ARG A CA  1 
ATOM   426   C C   . ARG A 1 76  ? 2.520   8.221   17.240  1.00 40.46  ? 76  ARG A C   1 
ATOM   427   O O   . ARG A 1 76  ? 2.957   8.433   18.379  1.00 42.58  ? 76  ARG A O   1 
ATOM   428   C CB  . ARG A 1 76  ? 1.532   10.397  16.548  1.00 42.84  ? 76  ARG A CB  1 
ATOM   429   C CG  . ARG A 1 76  ? 0.885   11.025  15.323  1.00 44.89  ? 76  ARG A CG  1 
ATOM   430   C CD  . ARG A 1 76  ? 0.468   12.469  15.617  1.00 50.71  ? 76  ARG A CD  1 
ATOM   431   N NE  . ARG A 1 76  ? -0.516  12.515  16.695  1.00 54.27  ? 76  ARG A NE  1 
ATOM   432   C CZ  . ARG A 1 76  ? -1.830  12.445  16.526  1.00 48.10  ? 76  ARG A CZ  1 
ATOM   433   N NH1 . ARG A 1 76  ? -2.370  12.409  15.319  1.00 51.94  ? 76  ARG A NH1 1 
ATOM   434   N NH2 . ARG A 1 76  ? -2.624  12.412  17.596  1.00 38.76  ? 76  ARG A NH2 1 
ATOM   435   N N   . THR A 1 77  ? 3.097   7.400   16.374  1.00 38.61  ? 77  THR A N   1 
ATOM   436   C CA  . THR A 1 77  ? 4.482   6.976   16.480  1.00 44.40  ? 77  THR A CA  1 
ATOM   437   C C   . THR A 1 77  ? 5.289   7.793   15.490  1.00 39.19  ? 77  THR A C   1 
ATOM   438   O O   . THR A 1 77  ? 4.805   8.114   14.404  1.00 42.84  ? 77  THR A O   1 
ATOM   439   C CB  . THR A 1 77  ? 4.653   5.486   16.168  1.00 34.66  ? 77  THR A CB  1 
ATOM   440   O OG1 . THR A 1 77  ? 4.374   5.252   14.778  1.00 35.30  ? 77  THR A OG1 1 
ATOM   441   C CG2 . THR A 1 77  ? 3.716   4.644   17.038  1.00 32.33  ? 77  THR A CG2 1 
ATOM   442   N N   . GLN A 1 78  ? 6.515   8.119   15.863  1.00 42.67  ? 78  GLN A N   1 
ATOM   443   C CA  . GLN A 1 78  ? 7.413   8.819   14.958  1.00 51.22  ? 78  GLN A CA  1 
ATOM   444   C C   . GLN A 1 78  ? 8.121   7.873   13.975  1.00 48.29  ? 78  GLN A C   1 
ATOM   445   O O   . GLN A 1 78  ? 9.142   8.261   13.402  1.00 52.99  ? 78  GLN A O   1 
ATOM   446   C CB  . GLN A 1 78  ? 8.445   9.614   15.765  1.00 51.01  ? 78  GLN A CB  1 
ATOM   447   C CG  . GLN A 1 78  ? 7.851   10.699  16.660  1.00 52.65  ? 78  GLN A CG  1 
ATOM   448   C CD  . GLN A 1 78  ? 8.922   11.483  17.411  1.00 60.34  ? 78  GLN A CD  1 
ATOM   449   O OE1 . GLN A 1 78  ? 9.870   11.985  16.812  1.00 57.91  ? 78  GLN A OE1 1 
ATOM   450   N NE2 . GLN A 1 78  ? 8.775   11.583  18.730  1.00 57.44  ? 78  GLN A NE2 1 
ATOM   451   N N   . THR A 1 79  ? 7.607   6.663   13.751  1.00 40.28  ? 79  THR A N   1 
ATOM   452   C CA  . THR A 1 79  ? 8.363   5.636   13.048  1.00 42.99  ? 79  THR A CA  1 
ATOM   453   C C   . THR A 1 79  ? 7.399   4.616   12.477  1.00 42.33  ? 79  THR A C   1 
ATOM   454   O O   . THR A 1 79  ? 6.337   4.381   13.065  1.00 41.12  ? 79  THR A O   1 
ATOM   455   C CB  . THR A 1 79  ? 9.343   4.936   14.000  1.00 45.46  ? 79  THR A CB  1 
ATOM   456   O OG1 . THR A 1 79  ? 8.725   4.822   15.287  1.00 48.84  ? 79  THR A OG1 1 
ATOM   457   C CG2 . THR A 1 79  ? 10.664  5.707   14.127  1.00 53.24  ? 79  THR A CG2 1 
ATOM   458   N N   . PRO A 1 80  ? 7.745   3.971   11.360  1.00 43.18  ? 80  PRO A N   1 
ATOM   459   C CA  . PRO A 1 80  ? 6.968   2.818   10.890  1.00 37.74  ? 80  PRO A CA  1 
ATOM   460   C C   . PRO A 1 80  ? 6.740   1.815   12.010  1.00 37.45  ? 80  PRO A C   1 
ATOM   461   O O   . PRO A 1 80  ? 7.535   1.715   12.945  1.00 39.96  ? 80  PRO A O   1 
ATOM   462   C CB  . PRO A 1 80  ? 7.855   2.223   9.793   1.00 36.90  ? 80  PRO A CB  1 
ATOM   463   C CG  . PRO A 1 80  ? 8.610   3.389   9.251   1.00 36.16  ? 80  PRO A CG  1 
ATOM   464   C CD  . PRO A 1 80  ? 8.790   4.367   10.392  1.00 42.77  ? 80  PRO A CD  1 
ATOM   465   N N   . LEU A 1 81  ? 5.660   1.043   11.890  1.00 32.20  ? 81  LEU A N   1 
ATOM   466   C CA  . LEU A 1 81  ? 5.240   0.134   12.959  1.00 31.86  ? 81  LEU A CA  1 
ATOM   467   C C   . LEU A 1 81  ? 5.913   -1.234  12.811  1.00 32.21  ? 81  LEU A C   1 
ATOM   468   O O   . LEU A 1 81  ? 5.266   -2.266  12.593  1.00 29.01  ? 81  LEU A O   1 
ATOM   469   C CB  . LEU A 1 81  ? 3.718   -0.001  12.981  1.00 26.07  ? 81  LEU A CB  1 
ATOM   470   C CG  . LEU A 1 81  ? 2.893   1.289   12.878  1.00 33.53  ? 81  LEU A CG  1 
ATOM   471   C CD1 . LEU A 1 81  ? 1.383   1.010   13.037  1.00 28.80  ? 81  LEU A CD1 1 
ATOM   472   C CD2 . LEU A 1 81  ? 3.372   2.331   13.869  1.00 31.91  ? 81  LEU A CD2 1 
ATOM   473   N N   . SER A 1 82  ? 7.239   -1.223  12.948  1.00 31.55  ? 82  SER A N   1 
ATOM   474   C CA  . SER A 1 82  ? 8.046   -2.426  12.810  1.00 24.64  ? 82  SER A CA  1 
ATOM   475   C C   . SER A 1 82  ? 7.768   -3.384  13.968  1.00 32.55  ? 82  SER A C   1 
ATOM   476   O O   . SER A 1 82  ? 7.051   -3.059  14.922  1.00 27.28  ? 82  SER A O   1 
ATOM   477   C CB  . SER A 1 82  ? 9.527   -2.069  12.810  1.00 29.11  ? 82  SER A CB  1 
ATOM   478   O OG  . SER A 1 82  ? 9.842   -1.432  14.041  1.00 28.99  ? 82  SER A OG  1 
ATOM   479   N N   . GLU A 1 83  ? 8.355   -4.587  13.885  1.00 25.11  ? 83  GLU A N   1 
ATOM   480   C CA  . GLU A 1 83  ? 8.247   -5.518  15.001  1.00 28.13  ? 83  GLU A CA  1 
ATOM   481   C C   . GLU A 1 83  ? 8.916   -4.936  16.241  1.00 28.76  ? 83  GLU A C   1 
ATOM   482   O O   . GLU A 1 83  ? 8.397   -5.065  17.362  1.00 26.01  ? 83  GLU A O   1 
ATOM   483   C CB  . GLU A 1 83  ? 8.869   -6.869  14.636  1.00 28.71  ? 83  GLU A CB  1 
ATOM   484   C CG  . GLU A 1 83  ? 8.135   -7.650  13.551  1.00 27.44  ? 83  GLU A CG  1 
ATOM   485   C CD  . GLU A 1 83  ? 6.754   -8.142  13.960  1.00 28.29  ? 83  GLU A CD  1 
ATOM   486   O OE1 . GLU A 1 83  ? 5.751   -7.392  13.794  1.00 21.12  ? 83  GLU A OE1 1 
ATOM   487   O OE2 . GLU A 1 83  ? 6.671   -9.306  14.430  1.00 29.30  ? 83  GLU A OE2 1 
ATOM   488   N N   . ALA A 1 84  ? 10.061  -4.271  16.049  1.00 24.00  ? 84  ALA A N   1 
ATOM   489   C CA  . ALA A 1 84  ? 10.741  -3.606  17.157  1.00 31.94  ? 84  ALA A CA  1 
ATOM   490   C C   . ALA A 1 84  ? 9.822   -2.612  17.861  1.00 28.46  ? 84  ALA A C   1 
ATOM   491   O O   . ALA A 1 84  ? 9.830   -2.511  19.090  1.00 33.21  ? 84  ALA A O   1 
ATOM   492   C CB  . ALA A 1 84  ? 12.008  -2.911  16.647  1.00 24.55  ? 84  ALA A CB  1 
ATOM   493   N N   . VAL A 1 85  ? 9.003   -1.885  17.107  1.00 29.33  ? 85  VAL A N   1 
ATOM   494   C CA  . VAL A 1 85  ? 8.103   -0.929  17.737  1.00 26.30  ? 85  VAL A CA  1 
ATOM   495   C C   . VAL A 1 85  ? 7.025   -1.650  18.544  1.00 28.09  ? 85  VAL A C   1 
ATOM   496   O O   . VAL A 1 85  ? 6.746   -1.290  19.692  1.00 26.81  ? 85  VAL A O   1 
ATOM   497   C CB  . VAL A 1 85  ? 7.505   0.015   16.682  1.00 26.75  ? 85  VAL A CB  1 
ATOM   498   C CG1 . VAL A 1 85  ? 6.430   0.891   17.315  1.00 28.44  ? 85  VAL A CG1 1 
ATOM   499   C CG2 . VAL A 1 85  ? 8.611   0.902   16.108  1.00 28.33  ? 85  VAL A CG2 1 
ATOM   500   N N   . LEU A 1 86  ? 6.417   -2.692  17.965  1.00 26.40  ? 86  LEU A N   1 
ATOM   501   C CA  . LEU A 1 86  ? 5.366   -3.430  18.651  1.00 22.61  ? 86  LEU A CA  1 
ATOM   502   C C   . LEU A 1 86  ? 5.875   -4.128  19.902  1.00 27.86  ? 86  LEU A C   1 
ATOM   503   O O   . LEU A 1 86  ? 5.069   -4.492  20.763  1.00 26.90  ? 86  LEU A O   1 
ATOM   504   C CB  . LEU A 1 86  ? 4.762   -4.469  17.707  1.00 22.31  ? 86  LEU A CB  1 
ATOM   505   C CG  . LEU A 1 86  ? 4.180   -4.024  16.362  1.00 27.85  ? 86  LEU A CG  1 
ATOM   506   C CD1 . LEU A 1 86  ? 3.410   -5.189  15.716  1.00 25.01  ? 86  LEU A CD1 1 
ATOM   507   C CD2 . LEU A 1 86  ? 3.288   -2.794  16.497  1.00 28.49  ? 86  LEU A CD2 1 
ATOM   508   N N   . GLN A 1 87  ? 7.186   -4.380  19.978  1.00 28.97  ? 87  GLN A N   1 
ATOM   509   C CA  . GLN A 1 87  ? 7.863   -4.926  21.146  1.00 29.60  ? 87  GLN A CA  1 
ATOM   510   C C   . GLN A 1 87  ? 8.255   -3.844  22.143  1.00 33.39  ? 87  GLN A C   1 
ATOM   511   O O   . GLN A 1 87  ? 8.475   -4.153  23.320  1.00 35.27  ? 87  GLN A O   1 
ATOM   512   C CB  . GLN A 1 87  ? 9.140   -5.669  20.703  1.00 32.48  ? 87  GLN A CB  1 
ATOM   513   C CG  . GLN A 1 87  ? 8.914   -7.033  20.035  1.00 35.19  ? 87  GLN A CG  1 
ATOM   514   C CD  . GLN A 1 87  ? 8.669   -8.157  21.035  1.00 49.42  ? 87  GLN A CD  1 
ATOM   515   O OE1 . GLN A 1 87  ? 9.514   -9.045  21.223  1.00 49.38  ? 87  GLN A OE1 1 
ATOM   516   N NE2 . GLN A 1 87  ? 7.520   -8.107  21.704  1.00 38.60  ? 87  GLN A NE2 1 
ATOM   517   N N   . ASP A 1 88  ? 8.338   -2.588  21.702  1.00 31.37  ? 88  ASP A N   1 
ATOM   518   C CA  . ASP A 1 88  ? 8.870   -1.507  22.526  1.00 32.93  ? 88  ASP A CA  1 
ATOM   519   C C   . ASP A 1 88  ? 8.032   -1.284  23.783  1.00 32.91  ? 88  ASP A C   1 
ATOM   520   O O   . ASP A 1 88  ? 6.833   -0.972  23.673  1.00 34.01  ? 88  ASP A O   1 
ATOM   521   C CB  . ASP A 1 88  ? 8.950   -0.213  21.722  1.00 32.18  ? 88  ASP A CB  1 
ATOM   522   C CG  . ASP A 1 88  ? 9.739   0.867   22.443  1.00 35.97  ? 88  ASP A CG  1 
ATOM   523   O OD1 . ASP A 1 88  ? 10.093  0.662   23.614  1.00 36.55  ? 88  ASP A OD1 1 
ATOM   524   O OD2 . ASP A 1 88  ? 10.030  1.913   21.843  1.00 41.59  ? 88  ASP A OD2 1 
ATOM   525   N N   . PRO A 1 89  ? 8.622   -1.396  24.986  1.00 37.80  ? 89  PRO A N   1 
ATOM   526   C CA  . PRO A 1 89  ? 7.826   -1.207  26.218  1.00 32.17  ? 89  PRO A CA  1 
ATOM   527   C C   . PRO A 1 89  ? 7.113   0.129   26.295  1.00 30.18  ? 89  PRO A C   1 
ATOM   528   O O   . PRO A 1 89  ? 5.999   0.201   26.834  1.00 27.88  ? 89  PRO A O   1 
ATOM   529   C CB  . PRO A 1 89  ? 8.873   -1.349  27.338  1.00 33.35  ? 89  PRO A CB  1 
ATOM   530   C CG  . PRO A 1 89  ? 9.978   -2.148  26.738  1.00 34.06  ? 89  PRO A CG  1 
ATOM   531   C CD  . PRO A 1 89  ? 10.019  -1.767  25.279  1.00 32.96  ? 89  PRO A CD  1 
ATOM   532   N N   . GLU A 1 90  ? 7.732   1.201   25.791  1.00 31.07  ? 90  GLU A N   1 
ATOM   533   C CA  . GLU A 1 90  ? 7.074   2.502   25.836  1.00 33.16  ? 90  GLU A CA  1 
ATOM   534   C C   . GLU A 1 90  ? 5.841   2.514   24.944  1.00 36.43  ? 90  GLU A C   1 
ATOM   535   O O   . GLU A 1 90  ? 4.760   2.927   25.374  1.00 32.74  ? 90  GLU A O   1 
ATOM   536   C CB  . GLU A 1 90  ? 8.049   3.602   25.430  1.00 39.49  ? 90  GLU A CB  1 
ATOM   537   C CG  . GLU A 1 90  ? 8.847   4.146   26.598  1.00 50.67  ? 90  GLU A CG  1 
ATOM   538   C CD  . GLU A 1 90  ? 9.679   5.355   26.223  1.00 65.72  ? 90  GLU A CD  1 
ATOM   539   O OE1 . GLU A 1 90  ? 9.773   6.283   27.063  1.00 67.33  ? 90  GLU A OE1 1 
ATOM   540   O OE2 . GLU A 1 90  ? 10.242  5.372   25.099  1.00 61.31  ? 90  GLU A OE2 1 
ATOM   541   N N   . PHE A 1 91  ? 5.985   2.040   23.699  1.00 34.42  ? 91  PHE A N   1 
ATOM   542   C CA  . PHE A 1 91  ? 4.841   1.912   22.799  1.00 31.16  ? 91  PHE A CA  1 
ATOM   543   C C   . PHE A 1 91  ? 3.739   1.093   23.436  1.00 24.53  ? 91  PHE A C   1 
ATOM   544   O O   . PHE A 1 91  ? 2.556   1.429   23.317  1.00 31.12  ? 91  PHE A O   1 
ATOM   545   C CB  . PHE A 1 91  ? 5.283   1.266   21.484  1.00 31.04  ? 91  PHE A CB  1 
ATOM   546   C CG  . PHE A 1 91  ? 4.160   0.952   20.527  1.00 28.21  ? 91  PHE A CG  1 
ATOM   547   C CD1 . PHE A 1 91  ? 3.666   1.929   19.661  1.00 26.83  ? 91  PHE A CD1 1 
ATOM   548   C CD2 . PHE A 1 91  ? 3.632   -0.335  20.452  1.00 26.73  ? 91  PHE A CD2 1 
ATOM   549   C CE1 . PHE A 1 91  ? 2.662   1.636   18.752  1.00 26.99  ? 91  PHE A CE1 1 
ATOM   550   C CE2 . PHE A 1 91  ? 2.610   -0.642  19.537  1.00 27.24  ? 91  PHE A CE2 1 
ATOM   551   C CZ  . PHE A 1 91  ? 2.124   0.345   18.692  1.00 29.74  ? 91  PHE A CZ  1 
ATOM   552   N N   . ILE A 1 92  ? 4.102   -0.005  24.092  1.00 27.00  ? 92  ILE A N   1 
ATOM   553   C CA  . ILE A 1 92  ? 3.083   -0.834  24.719  1.00 28.92  ? 92  ILE A CA  1 
ATOM   554   C C   . ILE A 1 92  ? 2.386   -0.047  25.819  1.00 30.17  ? 92  ILE A C   1 
ATOM   555   O O   . ILE A 1 92  ? 1.157   -0.116  25.973  1.00 31.68  ? 92  ILE A O   1 
ATOM   556   C CB  . ILE A 1 92  ? 3.702   -2.143  25.248  1.00 30.29  ? 92  ILE A CB  1 
ATOM   557   C CG1 . ILE A 1 92  ? 4.124   -3.047  24.091  1.00 32.73  ? 92  ILE A CG1 1 
ATOM   558   C CG2 . ILE A 1 92  ? 2.736   -2.887  26.168  1.00 26.01  ? 92  ILE A CG2 1 
ATOM   559   C CD1 . ILE A 1 92  ? 4.915   -4.270  24.527  1.00 30.63  ? 92  ILE A CD1 1 
ATOM   560   N N   . ASP A 1 93  ? 3.152   0.754   26.566  1.00 27.61  ? 93  ASP A N   1 
ATOM   561   C CA  . ASP A 1 93  ? 2.561   1.565   27.627  1.00 29.78  ? 93  ASP A CA  1 
ATOM   562   C C   . ASP A 1 93  ? 1.595   2.611   27.078  1.00 26.72  ? 93  ASP A C   1 
ATOM   563   O O   . ASP A 1 93  ? 0.596   2.932   27.730  1.00 26.21  ? 93  ASP A O   1 
ATOM   564   C CB  . ASP A 1 93  ? 3.665   2.233   28.461  1.00 29.30  ? 93  ASP A CB  1 
ATOM   565   C CG  . ASP A 1 93  ? 4.478   1.227   29.274  1.00 27.30  ? 93  ASP A CG  1 
ATOM   566   O OD1 . ASP A 1 93  ? 4.140   0.026   29.247  1.00 40.22  ? 93  ASP A OD1 1 
ATOM   567   O OD2 . ASP A 1 93  ? 5.463   1.623   29.935  1.00 33.44  ? 93  ASP A OD2 1 
ATOM   568   N N   . ARG A 1 94  ? 1.848   3.151   25.886  1.00 29.56  ? 94  ARG A N   1 
ATOM   569   C CA  . ARG A 1 94  ? 0.902   4.134   25.366  1.00 28.24  ? 94  ARG A CA  1 
ATOM   570   C C   . ARG A 1 94  ? -0.409  3.464   24.942  1.00 27.11  ? 94  ARG A C   1 
ATOM   571   O O   . ARG A 1 94  ? -1.485  4.031   25.137  1.00 30.95  ? 94  ARG A O   1 
ATOM   572   C CB  . ARG A 1 94  ? 1.528   4.924   24.217  1.00 31.42  ? 94  ARG A CB  1 
ATOM   573   C CG  . ARG A 1 94  ? 3.038   5.008   24.277  1.00 38.55  ? 94  ARG A CG  1 
ATOM   574   C CD  . ARG A 1 94  ? 3.620   6.342   23.820  1.00 35.93  ? 94  ARG A CD  1 
ATOM   575   N NE  . ARG A 1 94  ? 3.059   6.812   22.559  1.00 43.83  ? 94  ARG A NE  1 
ATOM   576   C CZ  . ARG A 1 94  ? 3.543   6.524   21.359  1.00 46.33  ? 94  ARG A CZ  1 
ATOM   577   N NH1 . ARG A 1 94  ? 4.598   5.737   21.207  1.00 49.78  ? 94  ARG A NH1 1 
ATOM   578   N NH2 . ARG A 1 94  ? 2.952   7.039   20.284  1.00 43.96  ? 94  ARG A NH2 1 
ATOM   579   N N   . LEU A 1 95  ? -0.350  2.246   24.393  1.00 25.34  ? 95  LEU A N   1 
ATOM   580   C CA  . LEU A 1 95  ? -1.582  1.542   24.051  1.00 23.43  ? 95  LEU A CA  1 
ATOM   581   C C   . LEU A 1 95  ? -2.318  1.058   25.303  1.00 28.28  ? 95  LEU A C   1 
ATOM   582   O O   . LEU A 1 95  ? -3.553  1.133   25.374  1.00 21.84  ? 95  LEU A O   1 
ATOM   583   C CB  . LEU A 1 95  ? -1.283  0.357   23.132  1.00 21.08  ? 95  LEU A CB  1 
ATOM   584   C CG  . LEU A 1 95  ? -0.741  0.674   21.736  1.00 29.23  ? 95  LEU A CG  1 
ATOM   585   C CD1 . LEU A 1 95  ? -0.651  -0.604  20.913  1.00 27.73  ? 95  LEU A CD1 1 
ATOM   586   C CD2 . LEU A 1 95  ? -1.607  1.705   21.045  1.00 29.15  ? 95  LEU A CD2 1 
ATOM   587   N N   . ALA A 1 96  ? -1.576  0.525   26.284  1.00 21.73  ? 96  ALA A N   1 
ATOM   588   C CA  . ALA A 1 96  ? -2.179  0.034   27.519  1.00 25.72  ? 96  ALA A CA  1 
ATOM   589   C C   . ALA A 1 96  ? -2.950  1.126   28.254  1.00 26.49  ? 96  ALA A C   1 
ATOM   590   O O   . ALA A 1 96  ? -3.946  0.832   28.924  1.00 26.95  ? 96  ALA A O   1 
ATOM   591   C CB  . ALA A 1 96  ? -1.092  -0.546  28.433  1.00 22.74  ? 96  ALA A CB  1 
ATOM   592   N N   . ALA A 1 97  ? -2.507  2.386   28.143  1.00 24.40  ? 97  ALA A N   1 
ATOM   593   C CA  . ALA A 1 97  ? -3.265  3.499   28.719  1.00 28.36  ? 97  ALA A CA  1 
ATOM   594   C C   . ALA A 1 97  ? -4.685  3.554   28.168  1.00 31.41  ? 97  ALA A C   1 
ATOM   595   O O   . ALA A 1 97  ? -5.597  4.067   28.837  1.00 30.08  ? 97  ALA A O   1 
ATOM   596   C CB  . ALA A 1 97  ? -2.546  4.818   28.452  1.00 21.46  ? 97  ALA A CB  1 
ATOM   597   N N   . HIS A 1 98  ? -4.900  3.022   26.963  1.00 24.61  ? 98  HIS A N   1 
ATOM   598   C CA  . HIS A 1 98  ? -6.260  2.885   26.462  1.00 25.46  ? 98  HIS A CA  1 
ATOM   599   C C   . HIS A 1 98  ? -6.897  1.571   26.883  1.00 29.58  ? 98  HIS A C   1 
ATOM   600   O O   . HIS A 1 98  ? -8.073  1.551   27.275  1.00 32.27  ? 98  HIS A O   1 
ATOM   601   C CB  . HIS A 1 98  ? -6.287  2.993   24.936  1.00 26.93  ? 98  HIS A CB  1 
ATOM   602   C CG  . HIS A 1 98  ? -5.936  4.347   24.418  1.00 21.77  ? 98  HIS A CG  1 
ATOM   603   N ND1 . HIS A 1 98  ? -6.879  5.329   24.213  1.00 29.90  ? 98  HIS A ND1 1 
ATOM   604   C CD2 . HIS A 1 98  ? -4.752  4.879   24.039  1.00 28.16  ? 98  HIS A CD2 1 
ATOM   605   C CE1 . HIS A 1 98  ? -6.292  6.413   23.740  1.00 24.79  ? 98  HIS A CE1 1 
ATOM   606   N NE2 . HIS A 1 98  ? -5.000  6.166   23.630  1.00 30.00  ? 98  HIS A NE2 1 
ATOM   607   N N   . THR A 1 99  ? -6.155  0.458   26.813  1.00 23.00  ? 99  THR A N   1 
ATOM   608   C CA  . THR A 1 99  ? -6.813  -0.829  26.960  1.00 26.31  ? 99  THR A CA  1 
ATOM   609   C C   . THR A 1 99  ? -7.065  -1.207  28.415  1.00 28.38  ? 99  THR A C   1 
ATOM   610   O O   . THR A 1 99  ? -7.999  -1.971  28.685  1.00 30.92  ? 99  THR A O   1 
ATOM   611   C CB  . THR A 1 99  ? -6.009  -1.908  26.230  1.00 29.50  ? 99  THR A CB  1 
ATOM   612   O OG1 . THR A 1 99  ? -4.677  -1.970  26.752  1.00 33.18  ? 99  THR A OG1 1 
ATOM   613   C CG2 . THR A 1 99  ? -5.933  -1.542  24.757  1.00 26.79  ? 99  THR A CG2 1 
ATOM   614   N N   . GLY A 1 100 ? -6.298  -0.662  29.351  1.00 30.91  ? 100 GLY A N   1 
ATOM   615   C CA  . GLY A 1 100 ? -6.614  -0.860  30.752  1.00 26.72  ? 100 GLY A CA  1 
ATOM   616   C C   . GLY A 1 100 ? -6.394  -2.304  31.146  1.00 29.23  ? 100 GLY A C   1 
ATOM   617   O O   . GLY A 1 100 ? -5.289  -2.841  31.027  1.00 31.19  ? 100 GLY A O   1 
ATOM   618   N N   . THR A 1 101 ? -7.452  -2.957  31.627  1.00 27.94  ? 101 THR A N   1 
ATOM   619   C CA  . THR A 1 101 ? -7.374  -4.380  31.922  1.00 30.43  ? 101 THR A CA  1 
ATOM   620   C C   . THR A 1 101 ? -7.329  -5.219  30.661  1.00 31.34  ? 101 THR A C   1 
ATOM   621   O O   . THR A 1 101 ? -6.915  -6.378  30.726  1.00 30.53  ? 101 THR A O   1 
ATOM   622   C CB  . THR A 1 101 ? -8.586  -4.821  32.724  1.00 30.68  ? 101 THR A CB  1 
ATOM   623   O OG1 . THR A 1 101 ? -9.735  -4.740  31.868  1.00 26.62  ? 101 THR A OG1 1 
ATOM   624   C CG2 . THR A 1 101 ? -8.790  -3.904  33.944  1.00 28.46  ? 101 THR A CG2 1 
ATOM   625   N N   . GLY A 1 102 ? -7.762  -4.658  29.524  1.00 33.68  ? 102 GLY A N   1 
ATOM   626   C CA  . GLY A 1 102 ? -7.887  -5.372  28.272  1.00 30.11  ? 102 GLY A CA  1 
ATOM   627   C C   . GLY A 1 102 ? -9.305  -5.778  27.925  1.00 28.82  ? 102 GLY A C   1 
ATOM   628   O O   . GLY A 1 102 ? -9.597  -6.006  26.745  1.00 26.95  ? 102 GLY A O   1 
ATOM   629   N N   . ALA A 1 103 ? -10.192 -5.855  28.918  1.00 28.50  ? 103 ALA A N   1 
ATOM   630   C CA  . ALA A 1 103 ? -11.535 -6.383  28.701  1.00 27.09  ? 103 ALA A CA  1 
ATOM   631   C C   . ALA A 1 103 ? -12.284 -5.541  27.685  1.00 23.64  ? 103 ALA A C   1 
ATOM   632   O O   . ALA A 1 103 ? -12.281 -4.308  27.759  1.00 27.69  ? 103 ALA A O   1 
ATOM   633   C CB  . ALA A 1 103 ? -12.307 -6.418  30.018  1.00 26.52  ? 103 ALA A CB  1 
ATOM   634   N N   . GLY A 1 104 ? -12.924 -6.211  26.735  1.00 24.49  ? 104 GLY A N   1 
ATOM   635   C CA  . GLY A 1 104 ? -13.617 -5.546  25.652  1.00 25.74  ? 104 GLY A CA  1 
ATOM   636   C C   . GLY A 1 104 ? -12.749 -5.067  24.501  1.00 25.45  ? 104 GLY A C   1 
ATOM   637   O O   . GLY A 1 104 ? -13.290 -4.509  23.538  1.00 29.73  ? 104 GLY A O   1 
ATOM   638   N N   . TRP A 1 105 ? -11.435 -5.256  24.549  1.00 22.44  ? 105 TRP A N   1 
ATOM   639   C CA  . TRP A 1 105 ? -10.551 -4.719  23.516  1.00 24.92  ? 105 TRP A CA  1 
ATOM   640   C C   . TRP A 1 105 ? -10.002 -5.819  22.612  1.00 24.12  ? 105 TRP A C   1 
ATOM   641   O O   . TRP A 1 105 ? -9.763  -6.943  23.050  1.00 28.01  ? 105 TRP A O   1 
ATOM   642   C CB  . TRP A 1 105 ? -9.380  -3.950  24.132  1.00 22.09  ? 105 TRP A CB  1 
ATOM   643   C CG  . TRP A 1 105 ? -9.745  -2.579  24.598  1.00 30.03  ? 105 TRP A CG  1 
ATOM   644   C CD1 . TRP A 1 105 ? -10.346 -2.247  25.783  1.00 26.51  ? 105 TRP A CD1 1 
ATOM   645   C CD2 . TRP A 1 105 ? -9.564  -1.354  23.881  1.00 27.78  ? 105 TRP A CD2 1 
ATOM   646   N NE1 . TRP A 1 105 ? -10.539 -0.889  25.845  1.00 28.71  ? 105 TRP A NE1 1 
ATOM   647   C CE2 . TRP A 1 105 ? -10.065 -0.317  24.694  1.00 30.42  ? 105 TRP A CE2 1 
ATOM   648   C CE3 . TRP A 1 105 ? -9.018  -1.030  22.634  1.00 31.23  ? 105 TRP A CE3 1 
ATOM   649   C CZ2 . TRP A 1 105 ? -10.036 1.025   24.302  1.00 30.40  ? 105 TRP A CZ2 1 
ATOM   650   C CZ3 . TRP A 1 105 ? -8.990  0.311   22.245  1.00 29.22  ? 105 TRP A CZ3 1 
ATOM   651   C CH2 . TRP A 1 105 ? -9.499  1.318   23.080  1.00 28.77  ? 105 TRP A CH2 1 
ATOM   652   N N   . SER A 1 106 ? -9.816  -5.491  21.337  1.00 27.04  ? 106 SER A N   1 
ATOM   653   C CA  . SER A 1 106 ? -9.116  -6.373  20.414  1.00 25.50  ? 106 SER A CA  1 
ATOM   654   C C   . SER A 1 106 ? -8.083  -5.553  19.653  1.00 26.46  ? 106 SER A C   1 
ATOM   655   O O   . SER A 1 106 ? -8.126  -4.315  19.651  1.00 21.89  ? 106 SER A O   1 
ATOM   656   C CB  . SER A 1 106 ? -10.060 -7.061  19.421  1.00 25.47  ? 106 SER A CB  1 
ATOM   657   O OG  . SER A 1 106 ? -11.068 -6.179  18.977  1.00 27.01  ? 106 SER A OG  1 
ATOM   658   N N   . LEU A 1 107 ? -7.148  -6.262  19.017  1.00 23.70  ? 107 LEU A N   1 
ATOM   659   C CA  . LEU A 1 107 ? -6.167  -5.670  18.116  1.00 21.20  ? 107 LEU A CA  1 
ATOM   660   C C   . LEU A 1 107 ? -6.576  -5.958  16.677  1.00 21.02  ? 107 LEU A C   1 
ATOM   661   O O   . LEU A 1 107 ? -6.993  -7.068  16.356  1.00 27.11  ? 107 LEU A O   1 
ATOM   662   C CB  . LEU A 1 107 ? -4.760  -6.226  18.382  1.00 20.13  ? 107 LEU A CB  1 
ATOM   663   C CG  . LEU A 1 107 ? -3.604  -5.754  17.477  1.00 20.77  ? 107 LEU A CG  1 
ATOM   664   C CD1 . LEU A 1 107 ? -3.234  -4.281  17.747  1.00 20.50  ? 107 LEU A CD1 1 
ATOM   665   C CD2 . LEU A 1 107 ? -2.348  -6.615  17.609  1.00 19.20  ? 107 LEU A CD2 1 
ATOM   666   N N   . PHE A 1 108 ? -6.453  -4.954  15.807  1.00 22.68  ? 108 PHE A N   1 
ATOM   667   C CA  . PHE A 1 108 ? -6.912  -5.038  14.422  1.00 19.13  ? 108 PHE A CA  1 
ATOM   668   C C   . PHE A 1 108 ? -5.707  -4.718  13.550  1.00 19.39  ? 108 PHE A C   1 
ATOM   669   O O   . PHE A 1 108 ? -5.545  -3.582  13.098  1.00 18.68  ? 108 PHE A O   1 
ATOM   670   C CB  . PHE A 1 108 ? -8.079  -4.083  14.163  1.00 21.17  ? 108 PHE A CB  1 
ATOM   671   C CG  . PHE A 1 108 ? -8.707  -4.241  12.823  1.00 22.28  ? 108 PHE A CG  1 
ATOM   672   C CD1 . PHE A 1 108 ? -9.482  -5.351  12.531  1.00 22.27  ? 108 PHE A CD1 1 
ATOM   673   C CD2 . PHE A 1 108 ? -8.515  -3.276  11.838  1.00 22.58  ? 108 PHE A CD2 1 
ATOM   674   C CE1 . PHE A 1 108 ? -10.044 -5.506  11.285  1.00 24.55  ? 108 PHE A CE1 1 
ATOM   675   C CE2 . PHE A 1 108 ? -9.093  -3.412  10.601  1.00 22.09  ? 108 PHE A CE2 1 
ATOM   676   C CZ  . PHE A 1 108 ? -9.846  -4.541  10.315  1.00 25.15  ? 108 PHE A CZ  1 
ATOM   677   N N   . PRO A 1 109 ? -4.833  -5.706  13.298  1.00 23.10  ? 109 PRO A N   1 
ATOM   678   C CA  . PRO A 1 109 ? -3.538  -5.424  12.671  1.00 17.89  ? 109 PRO A CA  1 
ATOM   679   C C   . PRO A 1 109 ? -3.516  -5.764  11.195  1.00 19.42  ? 109 PRO A C   1 
ATOM   680   O O   . PRO A 1 109 ? -4.206  -6.682  10.746  1.00 19.49  ? 109 PRO A O   1 
ATOM   681   C CB  . PRO A 1 109 ? -2.590  -6.339  13.452  1.00 21.27  ? 109 PRO A CB  1 
ATOM   682   C CG  . PRO A 1 109 ? -3.472  -7.584  13.725  1.00 18.61  ? 109 PRO A CG  1 
ATOM   683   C CD  . PRO A 1 109 ? -4.931  -7.112  13.741  1.00 19.52  ? 109 PRO A CD  1 
ATOM   684   N N   . CYS A 1 110 ? -2.703  -5.041  10.436  1.00 21.84  ? 110 CYS A N   1 
ATOM   685   C CA  . CYS A 1 110 ? -2.630  -5.291  9.009   1.00 21.82  ? 110 CYS A CA  1 
ATOM   686   C C   . CYS A 1 110 ? -2.002  -6.652  8.730   1.00 24.09  ? 110 CYS A C   1 
ATOM   687   O O   . CYS A 1 110 ? -2.422  -7.365  7.813   1.00 22.31  ? 110 CYS A O   1 
ATOM   688   C CB  . CYS A 1 110 ? -1.832  -4.184  8.341   1.00 23.86  ? 110 CYS A CB  1 
ATOM   689   S SG  . CYS A 1 110 ? -1.705  -4.358  6.557   1.00 29.72  ? 110 CYS A SG  1 
ATOM   690   N N   . VAL A 1 111 ? -1.016  -7.035  9.528   1.00 22.29  ? 111 VAL A N   1 
ATOM   691   C CA  . VAL A 1 111 ? -0.201  -8.215  9.285   1.00 23.68  ? 111 VAL A CA  1 
ATOM   692   C C   . VAL A 1 111 ? -0.114  -8.953  10.611  1.00 25.68  ? 111 VAL A C   1 
ATOM   693   O O   . VAL A 1 111 ? 0.278   -8.362  11.624  1.00 25.31  ? 111 VAL A O   1 
ATOM   694   C CB  . VAL A 1 111 ? 1.202   -7.842  8.762   1.00 26.54  ? 111 VAL A CB  1 
ATOM   695   C CG1 . VAL A 1 111 ? 1.977   -9.058  8.381   1.00 23.88  ? 111 VAL A CG1 1 
ATOM   696   C CG2 . VAL A 1 111 ? 1.120   -6.923  7.551   1.00 25.82  ? 111 VAL A CG2 1 
ATOM   697   N N   . SER A 1 112 ? -0.514  -10.223 10.627  1.00 21.14  ? 112 SER A N   1 
ATOM   698   C CA  . SER A 1 112 ? -0.535  -10.968 11.881  1.00 20.35  ? 112 SER A CA  1 
ATOM   699   C C   . SER A 1 112 ? 0.868   -11.513 12.168  1.00 27.95  ? 112 SER A C   1 
ATOM   700   O O   . SER A 1 112 ? 1.157   -12.707 12.054  1.00 24.24  ? 112 SER A O   1 
ATOM   701   C CB  . SER A 1 112 ? -1.576  -12.073 11.833  1.00 22.66  ? 112 SER A CB  1 
ATOM   702   O OG  . SER A 1 112 ? -2.859  -11.586 12.205  1.00 29.03  ? 112 SER A OG  1 
ATOM   703   N N   . THR A 1 113 ? 1.752   -10.607 12.566  1.00 20.35  ? 113 THR A N   1 
ATOM   704   C CA  . THR A 1 113 ? 3.110   -11.014 12.862  1.00 21.84  ? 113 THR A CA  1 
ATOM   705   C C   . THR A 1 113 ? 3.235   -11.556 14.284  1.00 21.46  ? 113 THR A C   1 
ATOM   706   O O   . THR A 1 113 ? 2.339   -11.429 15.111  1.00 24.04  ? 113 THR A O   1 
ATOM   707   C CB  . THR A 1 113 ? 4.055   -9.841  12.707  1.00 26.61  ? 113 THR A CB  1 
ATOM   708   O OG1 . THR A 1 113 ? 3.748   -8.869  13.721  1.00 22.12  ? 113 THR A OG1 1 
ATOM   709   C CG2 . THR A 1 113 ? 3.878   -9.216  11.347  1.00 25.63  ? 113 THR A CG2 1 
ATOM   710   N N   . ARG A 1 114 ? 4.405   -12.125 14.564  1.00 20.62  ? 114 ARG A N   1 
ATOM   711   C CA  . ARG A 1 114 ? 4.730   -12.605 15.900  1.00 19.13  ? 114 ARG A CA  1 
ATOM   712   C C   . ARG A 1 114 ? 4.634   -11.493 16.933  1.00 20.07  ? 114 ARG A C   1 
ATOM   713   O O   . ARG A 1 114 ? 4.119   -11.702 18.033  1.00 21.05  ? 114 ARG A O   1 
ATOM   714   C CB  . ARG A 1 114 ? 6.135   -13.200 15.899  1.00 20.99  ? 114 ARG A CB  1 
ATOM   715   C CG  . ARG A 1 114 ? 6.669   -13.532 17.266  1.00 23.59  ? 114 ARG A CG  1 
ATOM   716   C CD  . ARG A 1 114 ? 8.042   -14.152 17.143  1.00 25.05  ? 114 ARG A CD  1 
ATOM   717   N NE  . ARG A 1 114 ? 8.642   -14.357 18.448  1.00 25.37  ? 114 ARG A NE  1 
ATOM   718   C CZ  . ARG A 1 114 ? 8.451   -15.441 19.185  1.00 22.36  ? 114 ARG A CZ  1 
ATOM   719   N NH1 . ARG A 1 114 ? 7.632   -16.399 18.797  1.00 24.55  ? 114 ARG A NH1 1 
ATOM   720   N NH2 . ARG A 1 114 ? 9.115   -15.575 20.331  1.00 24.33  ? 114 ARG A NH2 1 
ATOM   721   N N   . ALA A 1 115 ? 5.147   -10.310 16.611  1.00 21.85  ? 115 ALA A N   1 
ATOM   722   C CA  . ALA A 1 115 ? 5.033   -9.211  17.559  1.00 23.03  ? 115 ALA A CA  1 
ATOM   723   C C   . ALA A 1 115 ? 3.587   -8.783  17.747  1.00 22.05  ? 115 ALA A C   1 
ATOM   724   O O   . ALA A 1 115 ? 3.201   -8.399  18.857  1.00 22.93  ? 115 ALA A O   1 
ATOM   725   C CB  . ALA A 1 115 ? 5.881   -8.027  17.109  1.00 24.34  ? 115 ALA A CB  1 
ATOM   726   N N   . ALA A 1 116 ? 2.769   -8.855  16.693  1.00 21.85  ? 116 ALA A N   1 
ATOM   727   C CA  . ALA A 1 116 ? 1.360   -8.503  16.845  1.00 20.76  ? 116 ALA A CA  1 
ATOM   728   C C   . ALA A 1 116 ? 0.662   -9.460  17.797  1.00 23.64  ? 116 ALA A C   1 
ATOM   729   O O   . ALA A 1 116 ? -0.152  -9.035  18.631  1.00 22.93  ? 116 ALA A O   1 
ATOM   730   C CB  . ALA A 1 116 ? 0.650   -8.490  15.487  1.00 23.03  ? 116 ALA A CB  1 
ATOM   731   N N   . ALA A 1 117 ? 0.972   -10.760 17.687  1.00 23.15  ? 117 ALA A N   1 
ATOM   732   C CA  . ALA A 1 117 ? 0.375   -11.737 18.589  1.00 23.48  ? 117 ALA A CA  1 
ATOM   733   C C   . ALA A 1 117 ? 0.920   -11.561 19.997  1.00 22.43  ? 117 ALA A C   1 
ATOM   734   O O   . ALA A 1 117 ? 0.168   -11.624 20.976  1.00 21.15  ? 117 ALA A O   1 
ATOM   735   C CB  . ALA A 1 117 ? 0.627   -13.159 18.081  1.00 22.04  ? 117 ALA A CB  1 
ATOM   736   N N   . GLN A 1 118 ? 2.229   -11.333 20.109  1.00 22.77  ? 118 GLN A N   1 
ATOM   737   C CA  . GLN A 1 118 ? 2.812   -10.959 21.392  1.00 25.02  ? 118 GLN A CA  1 
ATOM   738   C C   . GLN A 1 118 ? 2.096   -9.758  21.995  1.00 23.88  ? 118 GLN A C   1 
ATOM   739   O O   . GLN A 1 118 ? 1.794   -9.748  23.193  1.00 26.13  ? 118 GLN A O   1 
ATOM   740   C CB  . GLN A 1 118 ? 4.303   -10.662 21.217  1.00 22.28  ? 118 GLN A CB  1 
ATOM   741   C CG  . GLN A 1 118 ? 5.139   -11.929 21.082  1.00 25.71  ? 118 GLN A CG  1 
ATOM   742   C CD  . GLN A 1 118 ? 6.608   -11.660 20.835  1.00 23.43  ? 118 GLN A CD  1 
ATOM   743   O OE1 . GLN A 1 118 ? 6.976   -10.753 20.090  1.00 26.40  ? 118 GLN A OE1 1 
ATOM   744   N NE2 . GLN A 1 118 ? 7.462   -12.466 21.457  1.00 29.71  ? 118 GLN A NE2 1 
ATOM   745   N N   . LEU A 1 119 ? 1.817   -8.734  21.174  1.00 23.53  ? 119 LEU A N   1 
ATOM   746   C CA  . LEU A 1 119 ? 1.170   -7.516  21.673  1.00 21.47  ? 119 LEU A CA  1 
ATOM   747   C C   . LEU A 1 119 ? -0.161  -7.824  22.351  1.00 23.68  ? 119 LEU A C   1 
ATOM   748   O O   . LEU A 1 119 ? -0.457  -7.290  23.427  1.00 23.82  ? 119 LEU A O   1 
ATOM   749   C CB  . LEU A 1 119 ? 0.960   -6.535  20.531  1.00 22.22  ? 119 LEU A CB  1 
ATOM   750   C CG  . LEU A 1 119 ? 0.575   -5.101  20.876  1.00 28.66  ? 119 LEU A CG  1 
ATOM   751   C CD1 . LEU A 1 119 ? 1.516   -4.508  21.928  1.00 22.40  ? 119 LEU A CD1 1 
ATOM   752   C CD2 . LEU A 1 119 ? 0.577   -4.244  19.587  1.00 22.94  ? 119 LEU A CD2 1 
ATOM   753   N N   . THR A 1 120 ? -0.958  -8.717  21.757  1.00 22.16  ? 120 THR A N   1 
ATOM   754   C CA  . THR A 1 120 ? -2.250  -9.050  22.344  1.00 22.71  ? 120 THR A CA  1 
ATOM   755   C C   . THR A 1 120 ? -2.096  -9.746  23.691  1.00 27.37  ? 120 THR A C   1 
ATOM   756   O O   . THR A 1 120 ? -2.972  -9.618  24.545  1.00 25.43  ? 120 THR A O   1 
ATOM   757   C CB  . THR A 1 120 ? -3.055  -9.941  21.404  1.00 23.56  ? 120 THR A CB  1 
ATOM   758   O OG1 . THR A 1 120 ? -2.409  -11.218 21.311  1.00 21.08  ? 120 THR A OG1 1 
ATOM   759   C CG2 . THR A 1 120 ? -3.181  -9.295  20.020  1.00 18.82  ? 120 THR A CG2 1 
ATOM   760   N N   . ARG A 1 121 ? -1.017  -10.506 23.896  1.00 24.73  ? 121 ARG A N   1 
ATOM   761   C CA  . ARG A 1 121 ? -0.788  -11.075 25.222  1.00 31.87  ? 121 ARG A CA  1 
ATOM   762   C C   . ARG A 1 121 ? -0.355  -10.004 26.223  1.00 31.64  ? 121 ARG A C   1 
ATOM   763   O O   . ARG A 1 121 ? -0.852  -9.979  27.351  1.00 31.74  ? 121 ARG A O   1 
ATOM   764   C CB  . ARG A 1 121 ? 0.247   -12.193 25.162  1.00 34.39  ? 121 ARG A CB  1 
ATOM   765   C CG  . ARG A 1 121 ? 0.371   -12.992 26.461  1.00 40.52  ? 121 ARG A CG  1 
ATOM   766   C CD  . ARG A 1 121 ? 0.490   -14.486 26.198  1.00 42.82  ? 121 ARG A CD  1 
ATOM   767   N NE  . ARG A 1 121 ? -0.477  -15.001 25.230  1.00 46.41  ? 121 ARG A NE  1 
ATOM   768   C CZ  . ARG A 1 121 ? -0.910  -16.260 25.180  1.00 43.90  ? 121 ARG A CZ  1 
ATOM   769   N NH1 . ARG A 1 121 ? -0.430  -17.181 26.008  1.00 47.17  ? 121 ARG A NH1 1 
ATOM   770   N NH2 . ARG A 1 121 ? -1.816  -16.610 24.241  1.00 53.51  ? 121 ARG A NH2 1 
ATOM   771   N N   . LYS A 1 122 ? 0.548   -9.097  25.826  1.00 30.59  ? 122 LYS A N   1 
ATOM   772   C CA  . LYS A 1 122 ? 1.045   -8.082  26.761  1.00 29.77  ? 122 LYS A CA  1 
ATOM   773   C C   . LYS A 1 122 ? -0.023  -7.073  27.157  1.00 29.42  ? 122 LYS A C   1 
ATOM   774   O O   . LYS A 1 122 ? 0.102   -6.440  28.206  1.00 35.40  ? 122 LYS A O   1 
ATOM   775   C CB  . LYS A 1 122 ? 2.232   -7.309  26.180  1.00 34.70  ? 122 LYS A CB  1 
ATOM   776   C CG  . LYS A 1 122 ? 3.507   -8.103  25.959  1.00 38.15  ? 122 LYS A CG  1 
ATOM   777   C CD  . LYS A 1 122 ? 4.635   -7.526  26.801  1.00 48.10  ? 122 LYS A CD  1 
ATOM   778   C CE  . LYS A 1 122 ? 6.014   -7.904  26.267  1.00 46.43  ? 122 LYS A CE  1 
ATOM   779   N NZ  . LYS A 1 122 ? 6.523   -9.224  26.738  1.00 46.92  ? 122 LYS A NZ  1 
ATOM   780   N N   . LEU A 1 123 ? -1.046  -6.867  26.325  1.00 31.88  ? 123 LEU A N   1 
ATOM   781   C CA  . LEU A 1 123 ? -2.147  -5.977  26.671  1.00 25.88  ? 123 LEU A CA  1 
ATOM   782   C C   . LEU A 1 123 ? -3.323  -6.713  27.307  1.00 25.99  ? 123 LEU A C   1 
ATOM   783   O O   . LEU A 1 123 ? -4.258  -6.065  27.776  1.00 30.43  ? 123 LEU A O   1 
ATOM   784   C CB  . LEU A 1 123 ? -2.617  -5.215  25.423  1.00 25.31  ? 123 LEU A CB  1 
ATOM   785   C CG  . LEU A 1 123 ? -1.593  -4.214  24.874  1.00 29.50  ? 123 LEU A CG  1 
ATOM   786   C CD1 . LEU A 1 123 ? -2.030  -3.560  23.563  1.00 22.71  ? 123 LEU A CD1 1 
ATOM   787   C CD2 . LEU A 1 123 ? -1.302  -3.152  25.943  1.00 28.18  ? 123 LEU A CD2 1 
ATOM   788   N N   . ASN A 1 124 ? -3.307  -8.040  27.333  1.00 28.71  ? 124 ASN A N   1 
ATOM   789   C CA  . ASN A 1 124 ? -4.431  -8.845  27.823  1.00 32.17  ? 124 ASN A CA  1 
ATOM   790   C C   . ASN A 1 124 ? -5.725  -8.581  27.044  1.00 31.47  ? 124 ASN A C   1 
ATOM   791   O O   . ASN A 1 124 ? -6.834  -8.818  27.540  1.00 29.62  ? 124 ASN A O   1 
ATOM   792   C CB  . ASN A 1 124 ? -4.662  -8.626  29.315  1.00 30.66  ? 124 ASN A CB  1 
ATOM   793   C CG  . ASN A 1 124 ? -5.491  -9.711  29.920  1.00 37.00  ? 124 ASN A CG  1 
ATOM   794   O OD1 . ASN A 1 124 ? -5.236  -10.895 29.693  1.00 39.94  ? 124 ASN A OD1 1 
ATOM   795   N ND2 . ASN A 1 124 ? -6.532  -9.322  30.661  1.00 38.53  ? 124 ASN A ND2 1 
ATOM   796   N N   . VAL A 1 125 ? -5.587  -8.100  25.822  1.00 24.99  ? 125 VAL A N   1 
ATOM   797   C CA  . VAL A 1 125 ? -6.674  -7.921  24.875  1.00 23.94  ? 125 VAL A CA  1 
ATOM   798   C C   . VAL A 1 125 ? -7.093  -9.306  24.363  1.00 26.92  ? 125 VAL A C   1 
ATOM   799   O O   . VAL A 1 125 ? -6.436  -10.300 24.678  1.00 29.05  ? 125 VAL A O   1 
ATOM   800   C CB  . VAL A 1 125 ? -6.139  -6.962  23.793  1.00 32.83  ? 125 VAL A CB  1 
ATOM   801   C CG1 . VAL A 1 125 ? -6.550  -7.317  22.389  1.00 26.93  ? 125 VAL A CG1 1 
ATOM   802   C CG2 . VAL A 1 125 ? -6.401  -5.496  24.188  1.00 25.23  ? 125 VAL A CG2 1 
ATOM   803   N N   . ALA A 1 126 ? -8.208  -9.413  23.634  1.00 23.78  ? 126 ALA A N   1 
ATOM   804   C CA  . ALA A 1 126 ? -8.599  -10.690 23.042  1.00 27.02  ? 126 ALA A CA  1 
ATOM   805   C C   . ALA A 1 126 ? -7.466  -11.270 22.217  1.00 25.12  ? 126 ALA A C   1 
ATOM   806   O O   . ALA A 1 126 ? -6.886  -10.598 21.359  1.00 26.32  ? 126 ALA A O   1 
ATOM   807   C CB  . ALA A 1 126 ? -9.838  -10.522 22.159  1.00 28.35  ? 126 ALA A CB  1 
ATOM   808   N N   . ALA A 1 127 ? -7.143  -12.513 22.497  1.00 26.76  ? 127 ALA A N   1 
ATOM   809   C CA  . ALA A 1 127 ? -6.038  -13.168 21.828  1.00 26.30  ? 127 ALA A CA  1 
ATOM   810   C C   . ALA A 1 127 ? -6.196  -13.091 20.313  1.00 23.68  ? 127 ALA A C   1 
ATOM   811   O O   . ALA A 1 127 ? -7.286  -13.298 19.778  1.00 24.04  ? 127 ALA A O   1 
ATOM   812   C CB  . ALA A 1 127 ? -5.995  -14.618 22.296  1.00 25.83  ? 127 ALA A CB  1 
ATOM   813   N N   . LEU A 1 128 ? -5.106  -12.766 19.624  1.00 23.75  ? 128 LEU A N   1 
ATOM   814   C CA  . LEU A 1 128 ? -5.108  -12.801 18.171  1.00 22.19  ? 128 LEU A CA  1 
ATOM   815   C C   . LEU A 1 128 ? -5.559  -14.169 17.665  1.00 25.27  ? 128 LEU A C   1 
ATOM   816   O O   . LEU A 1 128 ? -5.074  -15.214 18.122  1.00 24.59  ? 128 LEU A O   1 
ATOM   817   C CB  . LEU A 1 128 ? -3.710  -12.476 17.652  1.00 23.91  ? 128 LEU A CB  1 
ATOM   818   C CG  . LEU A 1 128 ? -3.585  -12.272 16.143  1.00 24.67  ? 128 LEU A CG  1 
ATOM   819   C CD1 . LEU A 1 128 ? -3.652  -10.819 15.808  1.00 28.67  ? 128 LEU A CD1 1 
ATOM   820   C CD2 . LEU A 1 128 ? -2.297  -12.873 15.613  1.00 29.70  ? 128 LEU A CD2 1 
ATOM   821   N N   . ASP A 1 129 ? -6.493  -14.166 16.725  1.00 22.97  ? 129 ASP A N   1 
ATOM   822   C CA  . ASP A 1 129 ? -6.901  -15.421 16.115  1.00 23.85  ? 129 ASP A CA  1 
ATOM   823   C C   . ASP A 1 129 ? -5.733  -15.976 15.303  1.00 22.05  ? 129 ASP A C   1 
ATOM   824   O O   . ASP A 1 129 ? -5.024  -15.231 14.624  1.00 20.89  ? 129 ASP A O   1 
ATOM   825   C CB  . ASP A 1 129 ? -8.146  -15.204 15.247  1.00 22.42  ? 129 ASP A CB  1 
ATOM   826   C CG  . ASP A 1 129 ? -8.883  -16.513 14.906  1.00 25.48  ? 129 ASP A CG  1 
ATOM   827   O OD1 . ASP A 1 129 ? -8.546  -17.577 15.454  1.00 27.56  ? 129 ASP A OD1 1 
ATOM   828   O OD2 . ASP A 1 129 ? -9.837  -16.473 14.101  1.00 35.74  ? 129 ASP A OD2 1 
ATOM   829   N N   . GLY A 1 130 ? -5.518  -17.283 15.393  1.00 19.08  ? 130 GLY A N   1 
ATOM   830   C CA  . GLY A 1 130 ? -4.336  -17.885 14.791  1.00 23.67  ? 130 GLY A CA  1 
ATOM   831   C C   . GLY A 1 130 ? -3.060  -17.522 15.511  1.00 24.32  ? 130 GLY A C   1 
ATOM   832   O O   . GLY A 1 130 ? -2.005  -17.373 14.873  1.00 20.80  ? 130 GLY A O   1 
ATOM   833   N N   . TYR A 1 131 ? -3.136  -17.391 16.836  1.00 23.21  ? 131 TYR A N   1 
ATOM   834   C CA  . TYR A 1 131 ? -2.009  -16.933 17.634  1.00 21.69  ? 131 TYR A CA  1 
ATOM   835   C C   . TYR A 1 131 ? -0.783  -17.820 17.433  1.00 23.77  ? 131 TYR A C   1 
ATOM   836   O O   . TYR A 1 131 ? 0.302   -17.330 17.093  1.00 26.20  ? 131 TYR A O   1 
ATOM   837   C CB  . TYR A 1 131 ? -2.442  -16.891 19.101  1.00 23.83  ? 131 TYR A CB  1 
ATOM   838   C CG  . TYR A 1 131 ? -1.365  -16.590 20.115  1.00 28.76  ? 131 TYR A CG  1 
ATOM   839   C CD1 . TYR A 1 131 ? -1.084  -15.273 20.489  1.00 27.51  ? 131 TYR A CD1 1 
ATOM   840   C CD2 . TYR A 1 131 ? -0.642  -17.625 20.731  1.00 28.21  ? 131 TYR A CD2 1 
ATOM   841   C CE1 . TYR A 1 131 ? -0.108  -14.990 21.430  1.00 25.95  ? 131 TYR A CE1 1 
ATOM   842   C CE2 . TYR A 1 131 ? 0.338   -17.348 21.684  1.00 31.58  ? 131 TYR A CE2 1 
ATOM   843   C CZ  . TYR A 1 131 ? 0.596   -16.027 22.032  1.00 32.36  ? 131 TYR A CZ  1 
ATOM   844   O OH  . TYR A 1 131 ? 1.564   -15.738 22.971  1.00 39.43  ? 131 TYR A OH  1 
ATOM   845   N N   . GLU A 1 132 ? -0.934  -19.129 17.643  1.00 24.57  ? 132 GLU A N   1 
ATOM   846   C CA  . GLU A 1 132 ? 0.216   -20.025 17.550  1.00 25.76  ? 132 GLU A CA  1 
ATOM   847   C C   . GLU A 1 132 ? 0.849   -19.964 16.172  1.00 20.86  ? 132 GLU A C   1 
ATOM   848   O O   . GLU A 1 132 ? 2.080   -19.975 16.044  1.00 22.96  ? 132 GLU A O   1 
ATOM   849   C CB  . GLU A 1 132 ? -0.189  -21.463 17.889  1.00 16.99  ? 132 GLU A CB  1 
ATOM   850   C CG  . GLU A 1 132 ? -0.599  -21.697 19.328  1.00 25.93  ? 132 GLU A CG  1 
ATOM   851   C CD  . GLU A 1 132 ? 0.343   -21.076 20.378  1.00 30.83  ? 132 GLU A CD  1 
ATOM   852   O OE1 . GLU A 1 132 ? 1.537   -20.874 20.089  1.00 33.95  ? 132 GLU A OE1 1 
ATOM   853   O OE2 . GLU A 1 132 ? -0.105  -20.818 21.521  1.00 32.14  ? 132 GLU A OE2 1 
ATOM   854   N N   . PHE A 1 133 ? 0.025   -19.860 15.132  1.00 22.33  ? 133 PHE A N   1 
ATOM   855   C CA  . PHE A 1 133 ? 0.547   -19.731 13.777  1.00 23.54  ? 133 PHE A CA  1 
ATOM   856   C C   . PHE A 1 133 ? 1.420   -18.493 13.660  1.00 22.06  ? 133 PHE A C   1 
ATOM   857   O O   . PHE A 1 133 ? 2.560   -18.557 13.176  1.00 23.30  ? 133 PHE A O   1 
ATOM   858   C CB  . PHE A 1 133 ? -0.619  -19.678 12.778  1.00 23.75  ? 133 PHE A CB  1 
ATOM   859   C CG  . PHE A 1 133 ? -0.198  -19.791 11.308  1.00 26.12  ? 133 PHE A CG  1 
ATOM   860   C CD1 . PHE A 1 133 ? 0.390   -20.962 10.816  1.00 22.57  ? 133 PHE A CD1 1 
ATOM   861   C CD2 . PHE A 1 133 ? -0.414  -18.733 10.427  1.00 24.19  ? 133 PHE A CD2 1 
ATOM   862   C CE1 . PHE A 1 133 ? 0.753   -21.074 9.477   1.00 25.04  ? 133 PHE A CE1 1 
ATOM   863   C CE2 . PHE A 1 133 ? -0.060  -18.831 9.078   1.00 23.87  ? 133 PHE A CE2 1 
ATOM   864   C CZ  . PHE A 1 133 ? 0.528   -20.003 8.600   1.00 18.95  ? 133 PHE A CZ  1 
ATOM   865   N N   . ALA A 1 134 ? 0.899   -17.353 14.119  1.00 20.33  ? 134 ALA A N   1 
ATOM   866   C CA  . ALA A 1 134 ? 1.637   -16.096 14.053  1.00 22.46  ? 134 ALA A CA  1 
ATOM   867   C C   . ALA A 1 134 ? 2.876   -16.124 14.946  1.00 22.51  ? 134 ALA A C   1 
ATOM   868   O O   . ALA A 1 134 ? 3.902   -15.549 14.595  1.00 20.23  ? 134 ALA A O   1 
ATOM   869   C CB  . ALA A 1 134 ? 0.714   -14.941 14.445  1.00 20.25  ? 134 ALA A CB  1 
ATOM   870   N N   . MET A 1 135 ? 2.783   -16.753 16.118  1.00 21.05  ? 135 MET A N   1 
ATOM   871   C CA  . MET A 1 135 ? 3.945   -16.905 16.991  1.00 21.58  ? 135 MET A CA  1 
ATOM   872   C C   . MET A 1 135 ? 5.124   -17.562 16.265  1.00 22.82  ? 135 MET A C   1 
ATOM   873   O O   . MET A 1 135 ? 6.283   -17.228 16.539  1.00 23.25  ? 135 MET A O   1 
ATOM   874   C CB  . MET A 1 135 ? 3.526   -17.712 18.226  1.00 25.69  ? 135 MET A CB  1 
ATOM   875   C CG  . MET A 1 135 ? 2.982   -16.912 19.423  1.00 26.03  ? 135 MET A CG  1 
ATOM   876   S SD  . MET A 1 135 ? 3.658   -15.248 19.661  1.00 28.03  ? 135 MET A SD  1 
ATOM   877   C CE  . MET A 1 135 ? 4.884   -15.627 20.906  1.00 23.62  ? 135 MET A CE  1 
ATOM   878   N N   . GLN A 1 136 ? 4.860   -18.475 15.327  1.00 22.86  ? 136 GLN A N   1 
ATOM   879   C CA  . GLN A 1 136 ? 5.911   -19.070 14.507  1.00 21.77  ? 136 GLN A CA  1 
ATOM   880   C C   . GLN A 1 136 ? 6.187   -18.284 13.223  1.00 25.09  ? 136 GLN A C   1 
ATOM   881   O O   . GLN A 1 136 ? 6.880   -18.795 12.325  1.00 22.85  ? 136 GLN A O   1 
ATOM   882   C CB  . GLN A 1 136 ? 5.555   -20.515 14.160  1.00 23.62  ? 136 GLN A CB  1 
ATOM   883   C CG  . GLN A 1 136 ? 5.341   -21.427 15.354  1.00 21.78  ? 136 GLN A CG  1 
ATOM   884   C CD  . GLN A 1 136 ? 6.519   -21.430 16.287  1.00 25.25  ? 136 GLN A CD  1 
ATOM   885   O OE1 . GLN A 1 136 ? 7.620   -21.795 15.884  1.00 26.77  ? 136 GLN A OE1 1 
ATOM   886   N NE2 . GLN A 1 136 ? 6.297   -21.049 17.555  1.00 24.30  ? 136 GLN A NE2 1 
ATOM   887   N N   . ASN A 1 137 ? 5.677   -17.053 13.134  1.00 19.48  ? 137 ASN A N   1 
ATOM   888   C CA  . ASN A 1 137 ? 5.711   -16.236 11.919  1.00 25.38  ? 137 ASN A CA  1 
ATOM   889   C C   . ASN A 1 137 ? 5.224   -17.024 10.707  1.00 26.59  ? 137 ASN A C   1 
ATOM   890   O O   . ASN A 1 137 ? 5.834   -17.019 9.633   1.00 21.41  ? 137 ASN A O   1 
ATOM   891   C CB  . ASN A 1 137 ? 7.103   -15.642 11.684  1.00 26.01  ? 137 ASN A CB  1 
ATOM   892   C CG  . ASN A 1 137 ? 7.395   -14.485 12.633  1.00 30.36  ? 137 ASN A CG  1 
ATOM   893   O OD1 . ASN A 1 137 ? 6.713   -13.440 12.608  1.00 28.96  ? 137 ASN A OD1 1 
ATOM   894   N ND2 . ASN A 1 137 ? 8.380   -14.680 13.501  1.00 24.86  ? 137 ASN A ND2 1 
ATOM   895   N N   . GLY A 1 138 ? 4.083   -17.681 10.896  1.00 23.49  ? 138 GLY A N   1 
ATOM   896   C CA  . GLY A 1 138 ? 3.496   -18.448 9.822   1.00 22.49  ? 138 GLY A CA  1 
ATOM   897   C C   . GLY A 1 138 ? 3.205   -17.610 8.604   1.00 25.05  ? 138 GLY A C   1 
ATOM   898   O O   . GLY A 1 138 ? 3.344   -18.089 7.477   1.00 22.86  ? 138 GLY A O   1 
ATOM   899   N N   . ILE A 1 139 ? 2.811   -16.348 8.803   1.00 25.37  ? 139 ILE A N   1 
ATOM   900   C CA  . ILE A 1 139 ? 2.343   -15.583 7.658   1.00 25.50  ? 139 ILE A CA  1 
ATOM   901   C C   . ILE A 1 139 ? 3.513   -15.081 6.821   1.00 28.88  ? 139 ILE A C   1 
ATOM   902   O O   . ILE A 1 139 ? 3.320   -14.730 5.651   1.00 31.50  ? 139 ILE A O   1 
ATOM   903   C CB  . ILE A 1 139 ? 1.384   -14.453 8.088   1.00 29.63  ? 139 ILE A CB  1 
ATOM   904   C CG1 . ILE A 1 139 ? 2.133   -13.271 8.665   1.00 28.59  ? 139 ILE A CG1 1 
ATOM   905   C CG2 . ILE A 1 139 ? 0.326   -14.948 9.084   1.00 24.58  ? 139 ILE A CG2 1 
ATOM   906   C CD1 . ILE A 1 139 ? 2.316   -12.242 7.667   1.00 30.80  ? 139 ILE A CD1 1 
ATOM   907   N N   . ASP A 1 140 ? 4.725   -15.043 7.373   1.00 28.13  ? 140 ASP A N   1 
ATOM   908   C CA  . ASP A 1 140 ? 5.897   -14.896 6.513   1.00 31.54  ? 140 ASP A CA  1 
ATOM   909   C C   . ASP A 1 140 ? 5.967   -16.024 5.485   1.00 30.77  ? 140 ASP A C   1 
ATOM   910   O O   . ASP A 1 140 ? 6.255   -15.783 4.306   1.00 30.18  ? 140 ASP A O   1 
ATOM   911   C CB  . ASP A 1 140 ? 7.186   -14.869 7.340   1.00 34.09  ? 140 ASP A CB  1 
ATOM   912   C CG  . ASP A 1 140 ? 7.509   -13.499 7.882   1.00 39.60  ? 140 ASP A CG  1 
ATOM   913   O OD1 . ASP A 1 140 ? 7.054   -12.495 7.282   1.00 48.96  ? 140 ASP A OD1 1 
ATOM   914   O OD2 . ASP A 1 140 ? 8.244   -13.425 8.902   1.00 43.67  ? 140 ASP A OD2 1 
ATOM   915   N N   . LEU A 1 141 ? 5.726   -17.266 5.918   1.00 24.94  ? 141 LEU A N   1 
ATOM   916   C CA  . LEU A 1 141 ? 5.715   -18.378 4.976   1.00 26.74  ? 141 LEU A CA  1 
ATOM   917   C C   . LEU A 1 141 ? 4.716   -18.135 3.853   1.00 27.78  ? 141 LEU A C   1 
ATOM   918   O O   . LEU A 1 141 ? 5.055   -18.268 2.675   1.00 26.27  ? 141 LEU A O   1 
ATOM   919   C CB  . LEU A 1 141 ? 5.391   -19.688 5.692   1.00 29.80  ? 141 LEU A CB  1 
ATOM   920   C CG  . LEU A 1 141 ? 5.562   -20.982 4.885   1.00 25.06  ? 141 LEU A CG  1 
ATOM   921   C CD1 . LEU A 1 141 ? 6.920   -21.017 4.185   1.00 23.88  ? 141 LEU A CD1 1 
ATOM   922   C CD2 . LEU A 1 141 ? 5.358   -22.187 5.805   1.00 23.12  ? 141 LEU A CD2 1 
ATOM   923   N N   . LEU A 1 142 ? 3.484   -17.743 4.202   1.00 23.89  ? 142 LEU A N   1 
ATOM   924   C CA  . LEU A 1 142 ? 2.431   -17.587 3.205   1.00 23.04  ? 142 LEU A CA  1 
ATOM   925   C C   . LEU A 1 142 ? 2.681   -16.410 2.267   1.00 25.32  ? 142 LEU A C   1 
ATOM   926   O O   . LEU A 1 142 ? 2.231   -16.433 1.119   1.00 29.61  ? 142 LEU A O   1 
ATOM   927   C CB  . LEU A 1 142 ? 1.075   -17.414 3.896   1.00 21.11  ? 142 LEU A CB  1 
ATOM   928   C CG  . LEU A 1 142 ? 0.614   -18.533 4.837   1.00 23.28  ? 142 LEU A CG  1 
ATOM   929   C CD1 . LEU A 1 142 ? -0.538  -18.077 5.696   1.00 22.64  ? 142 LEU A CD1 1 
ATOM   930   C CD2 . LEU A 1 142 ? 0.221   -19.748 4.064   1.00 24.10  ? 142 LEU A CD2 1 
ATOM   931   N N   . ASN A 1 143 ? 3.372   -15.374 2.724   1.00 21.95  ? 143 ASN A N   1 
ATOM   932   C CA  . ASN A 1 143 ? 3.557   -14.180 1.926   1.00 25.33  ? 143 ASN A CA  1 
ATOM   933   C C   . ASN A 1 143 ? 4.796   -14.236 1.047   1.00 25.12  ? 143 ASN A C   1 
ATOM   934   O O   . ASN A 1 143 ? 5.305   -13.190 0.642   1.00 27.61  ? 143 ASN A O   1 
ATOM   935   C CB  . ASN A 1 143 ? 3.603   -12.959 2.840   1.00 27.07  ? 143 ASN A CB  1 
ATOM   936   C CG  . ASN A 1 143 ? 2.227   -12.500 3.218   1.00 24.99  ? 143 ASN A CG  1 
ATOM   937   O OD1 . ASN A 1 143 ? 1.259   -12.794 2.518   1.00 30.20  ? 143 ASN A OD1 1 
ATOM   938   N ND2 . ASN A 1 143 ? 2.116   -11.811 4.339   1.00 32.63  ? 143 ASN A ND2 1 
ATOM   939   N N   . MET A 1 144 ? 5.303   -15.426 0.772   1.00 30.22  ? 144 MET A N   1 
ATOM   940   C CA  . MET A 1 144 ? 6.382   -15.626 -0.174  1.00 26.17  ? 144 MET A CA  1 
ATOM   941   C C   . MET A 1 144 ? 5.795   -16.056 -1.508  1.00 25.91  ? 144 MET A C   1 
ATOM   942   O O   . MET A 1 144 ? 4.804   -16.790 -1.552  1.00 24.95  ? 144 MET A O   1 
ATOM   943   C CB  . MET A 1 144 ? 7.358   -16.679 0.347   1.00 24.66  ? 144 MET A CB  1 
ATOM   944   C CG  . MET A 1 144 ? 8.132   -16.251 1.585   1.00 30.24  ? 144 MET A CG  1 
ATOM   945   S SD  . MET A 1 144 ? 8.900   -17.682 2.317   1.00 35.63  ? 144 MET A SD  1 
ATOM   946   C CE  . MET A 1 144 ? 10.352  -17.772 1.247   1.00 26.83  ? 144 MET A CE  1 
ATOM   947   N N   . LYS A 1 145 ? 6.398   -15.600 -2.602  1.00 29.60  ? 145 LYS A N   1 
ATOM   948   C CA  . LYS A 1 145 ? 5.839   -15.994 -3.885  1.00 23.13  ? 145 LYS A CA  1 
ATOM   949   C C   . LYS A 1 145 ? 6.180   -17.443 -4.219  1.00 26.46  ? 145 LYS A C   1 
ATOM   950   O O   . LYS A 1 145 ? 5.370   -18.135 -4.856  1.00 22.04  ? 145 LYS A O   1 
ATOM   951   C CB  . LYS A 1 145 ? 6.295   -15.034 -4.968  1.00 26.96  ? 145 LYS A CB  1 
ATOM   952   C CG  . LYS A 1 145 ? 5.685   -13.648 -4.803  1.00 35.57  ? 145 LYS A CG  1 
ATOM   953   C CD  . LYS A 1 145 ? 6.149   -12.676 -5.867  1.00 36.47  ? 145 LYS A CD  1 
ATOM   954   C CE  . LYS A 1 145 ? 5.863   -11.239 -5.445  1.00 37.01  ? 145 LYS A CE  1 
ATOM   955   N NZ  . LYS A 1 145 ? 5.861   -11.097 -3.959  1.00 41.07  ? 145 LYS A NZ  1 
ATOM   956   N N   . SER A 1 146 ? 7.339   -17.936 -3.765  1.00 19.06  ? 146 SER A N   1 
ATOM   957   C CA  . SER A 1 146 ? 7.655   -19.355 -3.963  1.00 26.26  ? 146 SER A CA  1 
ATOM   958   C C   . SER A 1 146 ? 6.636   -20.264 -3.270  1.00 21.43  ? 146 SER A C   1 
ATOM   959   O O   . SER A 1 146 ? 6.249   -21.308 -3.811  1.00 21.81  ? 146 SER A O   1 
ATOM   960   C CB  . SER A 1 146 ? 9.066   -19.657 -3.455  1.00 21.42  ? 146 SER A CB  1 
ATOM   961   O OG  . SER A 1 146 ? 9.315   -19.038 -2.202  1.00 24.64  ? 146 SER A OG  1 
ATOM   962   N N   . THR A 1 147 ? 6.223   -19.895 -2.058  1.00 19.97  ? 147 THR A N   1 
ATOM   963   C CA  . THR A 1 147 ? 5.228   -20.666 -1.316  1.00 19.93  ? 147 THR A CA  1 
ATOM   964   C C   . THR A 1 147 ? 3.913   -20.747 -2.077  1.00 21.02  ? 147 THR A C   1 
ATOM   965   O O   . THR A 1 147 ? 3.273   -21.804 -2.111  1.00 23.01  ? 147 THR A O   1 
ATOM   966   C CB  . THR A 1 147 ? 4.999   -20.018 0.054   1.00 21.52  ? 147 THR A CB  1 
ATOM   967   O OG1 . THR A 1 147 ? 6.184   -20.121 0.850   1.00 22.77  ? 147 THR A OG1 1 
ATOM   968   C CG2 . THR A 1 147 ? 3.832   -20.653 0.788   1.00 23.70  ? 147 THR A CG2 1 
ATOM   969   N N   . PHE A 1 148 ? 3.482   -19.639 -2.686  1.00 22.15  ? 148 PHE A N   1 
ATOM   970   C CA  . PHE A 1 148 ? 2.231   -19.672 -3.443  1.00 21.54  ? 148 PHE A CA  1 
ATOM   971   C C   . PHE A 1 148 ? 2.328   -20.634 -4.611  1.00 21.75  ? 148 PHE A C   1 
ATOM   972   O O   . PHE A 1 148 ? 1.459   -21.490 -4.792  1.00 23.34  ? 148 PHE A O   1 
ATOM   973   C CB  . PHE A 1 148 ? 1.840   -18.285 -3.972  1.00 20.27  ? 148 PHE A CB  1 
ATOM   974   C CG  . PHE A 1 148 ? 0.627   -18.332 -4.879  1.00 22.32  ? 148 PHE A CG  1 
ATOM   975   C CD1 . PHE A 1 148 ? -0.630  -18.571 -4.354  1.00 19.10  ? 148 PHE A CD1 1 
ATOM   976   C CD2 . PHE A 1 148 ? 0.760   -18.228 -6.266  1.00 28.27  ? 148 PHE A CD2 1 
ATOM   977   C CE1 . PHE A 1 148 ? -1.763  -18.657 -5.172  1.00 24.50  ? 148 PHE A CE1 1 
ATOM   978   C CE2 . PHE A 1 148 ? -0.365  -18.314 -7.103  1.00 30.33  ? 148 PHE A CE2 1 
ATOM   979   C CZ  . PHE A 1 148 ? -1.642  -18.535 -6.544  1.00 27.92  ? 148 PHE A CZ  1 
ATOM   980   N N   . ARG A 1 149 ? 3.367   -20.479 -5.438  1.00 20.93  ? 149 ARG A N   1 
ATOM   981   C CA  . ARG A 1 149 ? 3.565   -21.375 -6.574  1.00 25.59  ? 149 ARG A CA  1 
ATOM   982   C C   . ARG A 1 149 ? 3.545   -22.844 -6.143  1.00 21.54  ? 149 ARG A C   1 
ATOM   983   O O   . ARG A 1 149 ? 2.866   -23.674 -6.757  1.00 21.79  ? 149 ARG A O   1 
ATOM   984   C CB  . ARG A 1 149 ? 4.872   -21.000 -7.303  1.00 21.78  ? 149 ARG A CB  1 
ATOM   985   C CG  . ARG A 1 149 ? 4.704   -19.708 -8.164  1.00 28.04  ? 149 ARG A CG  1 
ATOM   986   C CD  . ARG A 1 149 ? 5.673   -19.607 -9.369  1.00 28.97  ? 149 ARG A CD  1 
ATOM   987   N NE  . ARG A 1 149 ? 5.606   -20.795 -10.210 1.00 23.09  ? 149 ARG A NE  1 
ATOM   988   C CZ  . ARG A 1 149 ? 4.808   -20.941 -11.257 1.00 29.36  ? 149 ARG A CZ  1 
ATOM   989   N NH1 . ARG A 1 149 ? 4.051   -19.943 -11.701 1.00 28.16  ? 149 ARG A NH1 1 
ATOM   990   N NH2 . ARG A 1 149 ? 4.764   -22.118 -11.875 1.00 23.98  ? 149 ARG A NH2 1 
ATOM   991   N N   . ARG A 1 150 ? 4.251   -23.173 -5.059  1.00 27.19  ? 150 ARG A N   1 
ATOM   992   C CA  . ARG A 1 150 ? 4.319   -24.557 -4.591  1.00 18.45  ? 150 ARG A CA  1 
ATOM   993   C C   . ARG A 1 150 ? 2.955   -25.059 -4.134  1.00 24.07  ? 150 ARG A C   1 
ATOM   994   O O   . ARG A 1 150 ? 2.462   -26.097 -4.605  1.00 22.81  ? 150 ARG A O   1 
ATOM   995   C CB  . ARG A 1 150 ? 5.329   -24.650 -3.450  1.00 22.64  ? 150 ARG A CB  1 
ATOM   996   C CG  . ARG A 1 150 ? 6.783   -24.632 -3.899  1.00 20.52  ? 150 ARG A CG  1 
ATOM   997   C CD  . ARG A 1 150 ? 7.650   -24.227 -2.718  1.00 26.42  ? 150 ARG A CD  1 
ATOM   998   N NE  . ARG A 1 150 ? 9.068   -24.203 -3.047  1.00 29.89  ? 150 ARG A NE  1 
ATOM   999   C CZ  . ARG A 1 150 ? 10.034  -23.763 -2.246  1.00 28.49  ? 150 ARG A CZ  1 
ATOM   1000  N NH1 . ARG A 1 150 ? 9.771   -23.203 -1.075  1.00 27.04  ? 150 ARG A NH1 1 
ATOM   1001  N NH2 . ARG A 1 150 ? 11.297  -23.890 -2.630  1.00 26.98  ? 150 ARG A NH2 1 
ATOM   1002  N N   . LEU A 1 151 ? 2.325   -24.332 -3.207  1.00 22.99  ? 151 LEU A N   1 
ATOM   1003  C CA  . LEU A 1 151 ? 1.003   -24.734 -2.729  1.00 23.71  ? 151 LEU A CA  1 
ATOM   1004  C C   . LEU A 1 151 ? 0.025   -24.882 -3.889  1.00 23.20  ? 151 LEU A C   1 
ATOM   1005  O O   . LEU A 1 151 ? -0.697  -25.884 -3.992  1.00 26.80  ? 151 LEU A O   1 
ATOM   1006  C CB  . LEU A 1 151 ? 0.477   -23.720 -1.710  1.00 17.94  ? 151 LEU A CB  1 
ATOM   1007  C CG  . LEU A 1 151 ? 1.376   -23.544 -0.485  1.00 27.06  ? 151 LEU A CG  1 
ATOM   1008  C CD1 . LEU A 1 151 ? 0.786   -22.530 0.488   1.00 31.15  ? 151 LEU A CD1 1 
ATOM   1009  C CD2 . LEU A 1 151 ? 1.629   -24.884 0.215   1.00 20.93  ? 151 LEU A CD2 1 
ATOM   1010  N N   . ALA A 1 152 ? 0.015   -23.905 -4.793  1.00 19.74  ? 152 ALA A N   1 
ATOM   1011  C CA  . ALA A 1 152 ? -0.938  -23.932 -5.898  1.00 22.09  ? 152 ALA A CA  1 
ATOM   1012  C C   . ALA A 1 152 ? -0.645  -25.071 -6.863  1.00 23.48  ? 152 ALA A C   1 
ATOM   1013  O O   . ALA A 1 152 ? -1.574  -25.699 -7.392  1.00 23.43  ? 152 ALA A O   1 
ATOM   1014  C CB  . ALA A 1 152 ? -0.921  -22.595 -6.633  1.00 24.62  ? 152 ALA A CB  1 
ATOM   1015  N N   . ALA A 1 153 ? 0.638   -25.345 -7.118  1.00 21.75  ? 153 ALA A N   1 
ATOM   1016  C CA  . ALA A 1 153 ? 0.969   -26.481 -7.967  1.00 23.63  ? 153 ALA A CA  1 
ATOM   1017  C C   . ALA A 1 153 ? 0.589   -27.787 -7.285  1.00 23.91  ? 153 ALA A C   1 
ATOM   1018  O O   . ALA A 1 153 ? 0.101   -28.719 -7.934  1.00 19.97  ? 153 ALA A O   1 
ATOM   1019  C CB  . ALA A 1 153 ? 2.453   -26.454 -8.322  1.00 22.64  ? 153 ALA A CB  1 
ATOM   1020  N N   . GLY A 1 154 ? 0.774   -27.868 -5.971  1.00 23.85  ? 154 GLY A N   1 
ATOM   1021  C CA  . GLY A 1 154 ? 0.317   -29.051 -5.261  1.00 24.87  ? 154 GLY A CA  1 
ATOM   1022  C C   . GLY A 1 154 ? -1.193  -29.187 -5.265  1.00 23.94  ? 154 GLY A C   1 
ATOM   1023  O O   . GLY A 1 154 ? -1.732  -30.282 -5.430  1.00 25.41  ? 154 GLY A O   1 
ATOM   1024  N N   . LEU A 1 155 ? -1.900  -28.078 -5.110  1.00 24.83  ? 155 LEU A N   1 
ATOM   1025  C CA  . LEU A 1 155 ? -3.348  -28.186 -4.991  1.00 25.56  ? 155 LEU A CA  1 
ATOM   1026  C C   . LEU A 1 155 ? -4.021  -28.391 -6.340  1.00 24.94  ? 155 LEU A C   1 
ATOM   1027  O O   . LEU A 1 155 ? -5.110  -28.965 -6.397  1.00 26.62  ? 155 LEU A O   1 
ATOM   1028  C CB  . LEU A 1 155 ? -3.913  -26.936 -4.313  1.00 24.43  ? 155 LEU A CB  1 
ATOM   1029  C CG  . LEU A 1 155 ? -5.373  -27.041 -3.900  1.00 30.47  ? 155 LEU A CG  1 
ATOM   1030  C CD1 . LEU A 1 155 ? -5.556  -28.213 -2.947  1.00 28.39  ? 155 LEU A CD1 1 
ATOM   1031  C CD2 . LEU A 1 155 ? -5.869  -25.719 -3.294  1.00 26.58  ? 155 LEU A CD2 1 
ATOM   1032  N N   . GLY A 1 156 ? -3.389  -27.949 -7.422  1.00 29.94  ? 156 GLY A N   1 
ATOM   1033  C CA  . GLY A 1 156 ? -4.021  -27.915 -8.719  1.00 26.62  ? 156 GLY A CA  1 
ATOM   1034  C C   . GLY A 1 156 ? -4.670  -26.595 -9.065  1.00 29.56  ? 156 GLY A C   1 
ATOM   1035  O O   . GLY A 1 156 ? -5.591  -26.575 -9.889  1.00 26.27  ? 156 GLY A O   1 
ATOM   1036  N N   . THR A 1 157 ? -4.242  -25.506 -8.454  1.00 23.50  ? 157 THR A N   1 
ATOM   1037  C CA  . THR A 1 157 ? -4.816  -24.209 -8.752  1.00 23.49  ? 157 THR A CA  1 
ATOM   1038  C C   . THR A 1 157 ? -4.223  -23.681 -10.055 1.00 25.54  ? 157 THR A C   1 
ATOM   1039  O O   . THR A 1 157 ? -3.006  -23.741 -10.236 1.00 26.54  ? 157 THR A O   1 
ATOM   1040  C CB  . THR A 1 157 ? -4.539  -23.240 -7.595  1.00 26.09  ? 157 THR A CB  1 
ATOM   1041  O OG1 . THR A 1 157 ? -4.927  -23.849 -6.354  1.00 23.29  ? 157 THR A OG1 1 
ATOM   1042  C CG2 . THR A 1 157 ? -5.284  -21.955 -7.767  1.00 27.55  ? 157 THR A CG2 1 
ATOM   1043  N N   . PRO A 1 158 ? -5.051  -23.150 -10.980 1.00 29.54  ? 158 PRO A N   1 
ATOM   1044  C CA  . PRO A 1 158 ? -4.524  -22.558 -12.226 1.00 28.73  ? 158 PRO A CA  1 
ATOM   1045  C C   . PRO A 1 158 ? -3.376  -21.584 -12.013 1.00 28.88  ? 158 PRO A C   1 
ATOM   1046  O O   . PRO A 1 158 ? -3.552  -20.551 -11.354 1.00 23.99  ? 158 PRO A O   1 
ATOM   1047  C CB  . PRO A 1 158 ? -5.741  -21.826 -12.807 1.00 29.19  ? 158 PRO A CB  1 
ATOM   1048  C CG  . PRO A 1 158 ? -6.933  -22.558 -12.247 1.00 32.24  ? 158 PRO A CG  1 
ATOM   1049  C CD  . PRO A 1 158 ? -6.523  -23.063 -10.890 1.00 27.75  ? 158 PRO A CD  1 
ATOM   1050  N N   . LEU A 1 159 ? -2.223  -21.891 -12.623 1.00 23.72  ? 159 LEU A N   1 
ATOM   1051  C CA  . LEU A 1 159 ? -0.943  -21.244 -12.373 1.00 24.34  ? 159 LEU A CA  1 
ATOM   1052  C C   . LEU A 1 159 ? -0.193  -21.097 -13.691 1.00 27.08  ? 159 LEU A C   1 
ATOM   1053  O O   . LEU A 1 159 ? -0.248  -21.986 -14.545 1.00 26.02  ? 159 LEU A O   1 
ATOM   1054  C CB  . LEU A 1 159 ? -0.113  -22.077 -11.378 1.00 28.39  ? 159 LEU A CB  1 
ATOM   1055  C CG  . LEU A 1 159 ? 1.128   -21.519 -10.667 1.00 31.65  ? 159 LEU A CG  1 
ATOM   1056  C CD1 . LEU A 1 159 ? 0.756   -20.459 -9.664  1.00 29.83  ? 159 LEU A CD1 1 
ATOM   1057  C CD2 . LEU A 1 159 ? 1.893   -22.640 -9.974  1.00 29.67  ? 159 LEU A CD2 1 
ATOM   1058  N N   . THR A 1 160 ? 0.492   -19.971 -13.872 1.00 28.41  ? 160 THR A N   1 
ATOM   1059  C CA  . THR A 1 160 ? 1.314   -19.830 -15.061 1.00 28.48  ? 160 THR A CA  1 
ATOM   1060  C C   . THR A 1 160 ? 2.545   -20.718 -14.951 1.00 29.61  ? 160 THR A C   1 
ATOM   1061  O O   . THR A 1 160 ? 3.057   -20.977 -13.855 1.00 27.15  ? 160 THR A O   1 
ATOM   1062  C CB  . THR A 1 160 ? 1.772   -18.388 -15.257 1.00 34.14  ? 160 THR A CB  1 
ATOM   1063  O OG1 . THR A 1 160 ? 2.507   -17.974 -14.102 1.00 37.20  ? 160 THR A OG1 1 
ATOM   1064  C CG2 . THR A 1 160 ? 0.592   -17.458 -15.480 1.00 31.53  ? 160 THR A CG2 1 
ATOM   1065  N N   . ASP A 1 161 ? 3.027   -21.180 -16.104 1.00 32.24  ? 161 ASP A N   1 
ATOM   1066  C CA  . ASP A 1 161 ? 4.308   -21.875 -16.146 1.00 29.99  ? 161 ASP A CA  1 
ATOM   1067  C C   . ASP A 1 161 ? 5.395   -20.998 -15.536 1.00 28.39  ? 161 ASP A C   1 
ATOM   1068  O O   . ASP A 1 161 ? 5.457   -19.791 -15.796 1.00 25.54  ? 161 ASP A O   1 
ATOM   1069  C CB  . ASP A 1 161 ? 4.654   -22.257 -17.584 1.00 28.24  ? 161 ASP A CB  1 
ATOM   1070  C CG  . ASP A 1 161 ? 3.678   -23.282 -18.169 1.00 45.34  ? 161 ASP A CG  1 
ATOM   1071  O OD1 . ASP A 1 161 ? 3.542   -23.359 -19.416 1.00 56.16  ? 161 ASP A OD1 1 
ATOM   1072  O OD2 . ASP A 1 161 ? 3.042   -24.025 -17.380 1.00 43.29  ? 161 ASP A OD2 1 
ATOM   1073  N N   . GLY A 1 162 ? 6.209   -21.596 -14.671 1.00 27.27  ? 162 GLY A N   1 
ATOM   1074  C CA  . GLY A 1 162 ? 7.232   -20.835 -13.971 1.00 30.67  ? 162 GLY A CA  1 
ATOM   1075  C C   . GLY A 1 162 ? 8.097   -21.712 -13.087 1.00 26.80  ? 162 GLY A C   1 
ATOM   1076  O O   . GLY A 1 162 ? 7.895   -22.918 -12.972 1.00 23.33  ? 162 GLY A O   1 
ATOM   1077  N N   . VAL A 1 163 ? 9.065   -21.074 -12.444 1.00 28.25  ? 163 VAL A N   1 
ATOM   1078  C CA  . VAL A 1 163 ? 10.083  -21.769 -11.673 1.00 28.42  ? 163 VAL A CA  1 
ATOM   1079  C C   . VAL A 1 163 ? 10.333  -20.995 -10.386 1.00 27.86  ? 163 VAL A C   1 
ATOM   1080  O O   . VAL A 1 163 ? 10.254  -19.762 -10.359 1.00 28.28  ? 163 VAL A O   1 
ATOM   1081  C CB  . VAL A 1 163 ? 11.387  -21.892 -12.485 1.00 30.54  ? 163 VAL A CB  1 
ATOM   1082  C CG1 . VAL A 1 163 ? 11.933  -20.520 -12.696 1.00 29.35  ? 163 VAL A CG1 1 
ATOM   1083  C CG2 . VAL A 1 163 ? 12.433  -22.720 -11.739 1.00 33.27  ? 163 VAL A CG2 1 
ATOM   1084  N N   . VAL A 1 164 ? 10.624  -21.723 -9.309  1.00 24.44  ? 164 VAL A N   1 
ATOM   1085  C CA  . VAL A 1 164 ? 11.181  -21.119 -8.106  1.00 26.45  ? 164 VAL A CA  1 
ATOM   1086  C C   . VAL A 1 164 ? 12.695  -21.197 -8.266  1.00 30.38  ? 164 VAL A C   1 
ATOM   1087  O O   . VAL A 1 164 ? 13.313  -22.233 -8.009  1.00 31.26  ? 164 VAL A O   1 
ATOM   1088  C CB  . VAL A 1 164 ? 10.706  -21.806 -6.826  1.00 25.87  ? 164 VAL A CB  1 
ATOM   1089  C CG1 . VAL A 1 164 ? 11.382  -21.173 -5.638  1.00 25.27  ? 164 VAL A CG1 1 
ATOM   1090  C CG2 . VAL A 1 164 ? 9.182   -21.713 -6.678  1.00 26.75  ? 164 VAL A CG2 1 
ATOM   1091  N N   . ALA A 1 165 ? 13.292  -20.099 -8.708  1.00 26.30  ? 165 ALA A N   1 
ATOM   1092  C CA  . ALA A 1 165 ? 14.692  -20.109 -9.074  1.00 26.58  ? 165 ALA A CA  1 
ATOM   1093  C C   . ALA A 1 165 ? 15.546  -19.934 -7.828  1.00 30.35  ? 165 ALA A C   1 
ATOM   1094  O O   . ALA A 1 165 ? 15.245  -19.097 -6.963  1.00 31.44  ? 165 ALA A O   1 
ATOM   1095  C CB  . ALA A 1 165 ? 14.980  -19.016 -10.103 1.00 29.21  ? 165 ALA A CB  1 
ATOM   1096  N N   . ARG A 1 166 ? 16.588  -20.766 -7.731  1.00 26.35  ? 166 ARG A N   1 
ATOM   1097  C CA  . ARG A 1 166 ? 17.475  -20.872 -6.578  1.00 28.87  ? 166 ARG A CA  1 
ATOM   1098  C C   . ARG A 1 166 ? 18.848  -20.274 -6.840  1.00 31.69  ? 166 ARG A C   1 
ATOM   1099  O O   . ARG A 1 166 ? 19.703  -20.312 -5.952  1.00 29.34  ? 166 ARG A O   1 
ATOM   1100  C CB  . ARG A 1 166 ? 17.666  -22.343 -6.173  1.00 29.04  ? 166 ARG A CB  1 
ATOM   1101  C CG  . ARG A 1 166 ? 16.487  -23.002 -5.508  1.00 33.02  ? 166 ARG A CG  1 
ATOM   1102  C CD  . ARG A 1 166 ? 16.498  -24.509 -5.701  1.00 36.80  ? 166 ARG A CD  1 
ATOM   1103  N NE  . ARG A 1 166 ? 16.509  -24.909 -7.103  1.00 37.75  ? 166 ARG A NE  1 
ATOM   1104  C CZ  . ARG A 1 166 ? 16.507  -26.168 -7.512  1.00 37.14  ? 166 ARG A CZ  1 
ATOM   1105  N NH1 . ARG A 1 166 ? 16.419  -27.168 -6.653  1.00 41.77  ? 166 ARG A NH1 1 
ATOM   1106  N NH2 . ARG A 1 166 ? 16.600  -26.430 -8.812  1.00 36.56  ? 166 ARG A NH2 1 
ATOM   1107  N N   . GLY A 1 167 ? 19.091  -19.765 -8.045  1.00 30.32  ? 167 GLY A N   1 
ATOM   1108  C CA  . GLY A 1 167 ? 20.341  -19.142 -8.386  1.00 30.83  ? 167 GLY A CA  1 
ATOM   1109  C C   . GLY A 1 167 ? 20.265  -18.591 -9.789  1.00 34.96  ? 167 GLY A C   1 
ATOM   1110  O O   . GLY A 1 167 ? 19.305  -18.853 -10.524 1.00 34.82  ? 167 GLY A O   1 
ATOM   1111  N N   . PRO A 1 168 ? 21.265  -17.797 -10.186 1.00 35.56  ? 168 PRO A N   1 
ATOM   1112  C CA  . PRO A 1 168 ? 21.213  -17.184 -11.525 1.00 37.06  ? 168 PRO A CA  1 
ATOM   1113  C C   . PRO A 1 168 ? 21.353  -18.186 -12.654 1.00 37.02  ? 168 PRO A C   1 
ATOM   1114  O O   . PRO A 1 168 ? 20.859  -17.913 -13.754 1.00 35.19  ? 168 PRO A O   1 
ATOM   1115  C CB  . PRO A 1 168 ? 22.373  -16.176 -11.506 1.00 37.75  ? 168 PRO A CB  1 
ATOM   1116  C CG  . PRO A 1 168 ? 23.283  -16.639 -10.425 1.00 35.45  ? 168 PRO A CG  1 
ATOM   1117  C CD  . PRO A 1 168 ? 22.420  -17.335 -9.399  1.00 33.90  ? 168 PRO A CD  1 
ATOM   1118  N N   . ALA A 1 169 ? 21.991  -19.341 -12.417 1.00 37.92  ? 169 ALA A N   1 
ATOM   1119  C CA  . ALA A 1 169 ? 21.999  -20.398 -13.424 1.00 37.80  ? 169 ALA A CA  1 
ATOM   1120  C C   . ALA A 1 169 ? 20.595  -20.939 -13.659 1.00 38.09  ? 169 ALA A C   1 
ATOM   1121  O O   . ALA A 1 169 ? 20.209  -21.220 -14.801 1.00 38.28  ? 169 ALA A O   1 
ATOM   1122  C CB  . ALA A 1 169 ? 22.944  -21.523 -13.010 1.00 41.19  ? 169 ALA A CB  1 
ATOM   1123  N N   . GLU A 1 170 ? 19.803  -21.072 -12.592 1.00 39.72  ? 170 GLU A N   1 
ATOM   1124  C CA  . GLU A 1 170 ? 18.411  -21.466 -12.773 1.00 36.40  ? 170 GLU A CA  1 
ATOM   1125  C C   . GLU A 1 170 ? 17.613  -20.354 -13.442 1.00 37.12  ? 170 GLU A C   1 
ATOM   1126  O O   . GLU A 1 170 ? 16.720  -20.626 -14.251 1.00 37.21  ? 170 GLU A O   1 
ATOM   1127  C CB  . GLU A 1 170 ? 17.781  -21.842 -11.435 1.00 39.51  ? 170 GLU A CB  1 
ATOM   1128  C CG  . GLU A 1 170 ? 16.767  -22.956 -11.562 1.00 38.78  ? 170 GLU A CG  1 
ATOM   1129  C CD  . GLU A 1 170 ? 16.626  -23.774 -10.292 1.00 39.63  ? 170 GLU A CD  1 
ATOM   1130  O OE1 . GLU A 1 170 ? 17.014  -23.295 -9.202  1.00 38.29  ? 170 GLU A OE1 1 
ATOM   1131  O OE2 . GLU A 1 170 ? 16.120  -24.909 -10.388 1.00 44.70  ? 170 GLU A OE2 1 
ATOM   1132  N N   . VAL A 1 171 ? 17.917  -19.094 -13.121 1.00 36.05  ? 171 VAL A N   1 
ATOM   1133  C CA  . VAL A 1 171 ? 17.265  -17.987 -13.817 1.00 31.92  ? 171 VAL A CA  1 
ATOM   1134  C C   . VAL A 1 171 ? 17.528  -18.082 -15.314 1.00 35.87  ? 171 VAL A C   1 
ATOM   1135  O O   . VAL A 1 171 ? 16.618  -17.919 -16.134 1.00 34.89  ? 171 VAL A O   1 
ATOM   1136  C CB  . VAL A 1 171 ? 17.748  -16.646 -13.245 1.00 32.15  ? 171 VAL A CB  1 
ATOM   1137  C CG1 . VAL A 1 171 ? 17.224  -15.493 -14.073 1.00 37.27  ? 171 VAL A CG1 1 
ATOM   1138  C CG2 . VAL A 1 171 ? 17.338  -16.511 -11.781 1.00 37.04  ? 171 VAL A CG2 1 
ATOM   1139  N N   . ARG A 1 172 ? 18.775  -18.379 -15.687 1.00 42.98  ? 172 ARG A N   1 
ATOM   1140  C CA  . ARG A 1 172 ? 19.176  -18.432 -17.089 1.00 40.73  ? 172 ARG A CA  1 
ATOM   1141  C C   . ARG A 1 172 ? 18.340  -19.435 -17.874 1.00 39.84  ? 172 ARG A C   1 
ATOM   1142  O O   . ARG A 1 172 ? 17.710  -19.089 -18.879 1.00 40.55  ? 172 ARG A O   1 
ATOM   1143  C CB  . ARG A 1 172 ? 20.659  -18.788 -17.179 1.00 47.87  ? 172 ARG A CB  1 
ATOM   1144  C CG  . ARG A 1 172 ? 21.165  -19.001 -18.601 1.00 47.70  ? 172 ARG A CG  1 
ATOM   1145  C CD  . ARG A 1 172 ? 22.634  -18.672 -18.686 1.00 52.54  ? 172 ARG A CD  1 
ATOM   1146  N NE  . ARG A 1 172 ? 23.410  -19.761 -19.259 1.00 62.94  ? 172 ARG A NE  1 
ATOM   1147  C CZ  . ARG A 1 172 ? 23.536  -19.990 -20.559 1.00 63.36  ? 172 ARG A CZ  1 
ATOM   1148  N NH1 . ARG A 1 172 ? 22.946  -19.217 -21.456 1.00 64.57  ? 172 ARG A NH1 1 
ATOM   1149  N NH2 . ARG A 1 172 ? 24.276  -21.017 -20.967 1.00 59.64  ? 172 ARG A NH2 1 
ATOM   1150  N N   . SER A 1 173 ? 18.331  -20.693 -17.428 1.00 37.70  ? 173 SER A N   1 
ATOM   1151  C CA  . SER A 1 173 ? 17.526  -21.714 -18.092 1.00 36.39  ? 173 SER A CA  1 
ATOM   1152  C C   . SER A 1 173 ? 16.037  -21.388 -18.052 1.00 39.01  ? 173 SER A C   1 
ATOM   1153  O O   . SER A 1 173 ? 15.313  -21.722 -18.994 1.00 41.17  ? 173 SER A O   1 
ATOM   1154  C CB  . SER A 1 173 ? 17.773  -23.079 -17.448 1.00 39.08  ? 173 SER A CB  1 
ATOM   1155  O OG  . SER A 1 173 ? 17.698  -22.995 -16.029 1.00 47.13  ? 173 SER A OG  1 
ATOM   1156  N N   . ALA A 1 174 ? 15.556  -20.751 -16.975 1.00 36.14  ? 174 ALA A N   1 
ATOM   1157  C CA  . ALA A 1 174 ? 14.120  -20.491 -16.850 1.00 34.06  ? 174 ALA A CA  1 
ATOM   1158  C C   . ALA A 1 174 ? 13.649  -19.407 -17.812 1.00 38.94  ? 174 ALA A C   1 
ATOM   1159  O O   . ALA A 1 174 ? 12.558  -19.515 -18.386 1.00 38.23  ? 174 ALA A O   1 
ATOM   1160  C CB  . ALA A 1 174 ? 13.773  -20.092 -15.423 1.00 30.68  ? 174 ALA A CB  1 
ATOM   1161  N N   . ILE A 1 175 ? 14.424  -18.333 -17.966 1.00 36.74  ? 175 ILE A N   1 
ATOM   1162  C CA  . ILE A 1 175 ? 14.099  -17.339 -18.984 1.00 37.76  ? 175 ILE A CA  1 
ATOM   1163  C C   . ILE A 1 175 ? 14.067  -17.992 -20.360 1.00 37.78  ? 175 ILE A C   1 
ATOM   1164  O O   . ILE A 1 175 ? 13.120  -17.812 -21.132 1.00 43.32  ? 175 ILE A O   1 
ATOM   1165  C CB  . ILE A 1 175 ? 15.102  -16.170 -18.941 1.00 39.43  ? 175 ILE A CB  1 
ATOM   1166  C CG1 . ILE A 1 175 ? 15.245  -15.653 -17.518 1.00 40.12  ? 175 ILE A CG1 1 
ATOM   1167  C CG2 . ILE A 1 175 ? 14.654  -15.042 -19.853 1.00 41.10  ? 175 ILE A CG2 1 
ATOM   1168  C CD1 . ILE A 1 175 ? 14.270  -14.583 -17.170 1.00 40.02  ? 175 ILE A CD1 1 
ATOM   1169  N N   . GLN A 1 176 ? 15.100  -18.770 -20.680 1.00 39.70  ? 176 GLN A N   1 
ATOM   1170  C CA  . GLN A 1 176 ? 15.190  -19.396 -21.996 1.00 44.55  ? 176 GLN A CA  1 
ATOM   1171  C C   . GLN A 1 176 ? 13.950  -20.232 -22.286 1.00 40.60  ? 176 GLN A C   1 
ATOM   1172  O O   . GLN A 1 176 ? 13.327  -20.087 -23.341 1.00 42.56  ? 176 GLN A O   1 
ATOM   1173  C CB  . GLN A 1 176 ? 16.460  -20.244 -22.070 1.00 45.25  ? 176 GLN A CB  1 
ATOM   1174  C CG  . GLN A 1 176 ? 16.911  -20.610 -23.478 1.00 55.81  ? 176 GLN A CG  1 
ATOM   1175  C CD  . GLN A 1 176 ? 18.420  -20.812 -23.569 1.00 57.45  ? 176 GLN A CD  1 
ATOM   1176  O OE1 . GLN A 1 176 ? 19.043  -21.381 -22.668 1.00 50.43  ? 176 GLN A OE1 1 
ATOM   1177  N NE2 . GLN A 1 176 ? 19.017  -20.312 -24.648 1.00 57.41  ? 176 GLN A NE2 1 
ATOM   1178  N N   . GLU A 1 177 ? 13.555  -21.077 -21.329 1.00 40.33  ? 177 GLU A N   1 
ATOM   1179  C CA  . GLU A 1 177 ? 12.351  -21.893 -21.465 1.00 38.92  ? 177 GLU A CA  1 
ATOM   1180  C C   . GLU A 1 177 ? 11.085  -21.041 -21.532 1.00 38.69  ? 177 GLU A C   1 
ATOM   1181  O O   . GLU A 1 177 ? 10.245  -21.223 -22.424 1.00 36.23  ? 177 GLU A O   1 
ATOM   1182  C CB  . GLU A 1 177 ? 12.258  -22.870 -20.296 1.00 36.07  ? 177 GLU A CB  1 
ATOM   1183  C CG  . GLU A 1 177 ? 11.782  -24.276 -20.658 1.00 50.78  ? 177 GLU A CG  1 
ATOM   1184  C CD  . GLU A 1 177 ? 12.937  -25.211 -20.979 1.00 61.71  ? 177 GLU A CD  1 
ATOM   1185  O OE1 . GLU A 1 177 ? 13.046  -25.673 -22.143 1.00 62.98  ? 177 GLU A OE1 1 
ATOM   1186  O OE2 . GLU A 1 177 ? 13.754  -25.460 -20.063 1.00 59.12  ? 177 GLU A OE2 1 
ATOM   1187  N N   . LEU A 1 178 ? 10.914  -20.118 -20.584 1.00 34.83  ? 178 LEU A N   1 
ATOM   1188  C CA  . LEU A 1 178 ? 9.614   -19.470 -20.410 1.00 32.54  ? 178 LEU A CA  1 
ATOM   1189  C C   . LEU A 1 178 ? 9.373   -18.308 -21.371 1.00 33.07  ? 178 LEU A C   1 
ATOM   1190  O O   . LEU A 1 178 ? 8.224   -17.881 -21.524 1.00 30.47  ? 178 LEU A O   1 
ATOM   1191  C CB  . LEU A 1 178 ? 9.465   -18.990 -18.963 1.00 29.06  ? 178 LEU A CB  1 
ATOM   1192  C CG  . LEU A 1 178 ? 9.613   -20.158 -17.974 1.00 29.75  ? 178 LEU A CG  1 
ATOM   1193  C CD1 . LEU A 1 178 ? 9.851   -19.668 -16.532 1.00 27.06  ? 178 LEU A CD1 1 
ATOM   1194  C CD2 . LEU A 1 178 ? 8.406   -21.092 -18.067 1.00 26.11  ? 178 LEU A CD2 1 
ATOM   1195  N N   . ILE A 1 179 ? 10.416  -17.792 -22.027 1.00 31.74  ? 179 ILE A N   1 
ATOM   1196  C CA  . ILE A 1 179 ? 10.235  -16.669 -22.940 1.00 33.17  ? 179 ILE A CA  1 
ATOM   1197  C C   . ILE A 1 179 ? 9.464   -17.068 -24.202 1.00 31.18  ? 179 ILE A C   1 
ATOM   1198  O O   . ILE A 1 179 ? 8.917   -16.199 -24.888 1.00 31.01  ? 179 ILE A O   1 
ATOM   1199  C CB  . ILE A 1 179 ? 11.618  -16.060 -23.272 1.00 38.06  ? 179 ILE A CB  1 
ATOM   1200  C CG1 . ILE A 1 179 ? 11.481  -14.710 -23.972 1.00 36.88  ? 179 ILE A CG1 1 
ATOM   1201  C CG2 . ILE A 1 179 ? 12.460  -17.023 -24.105 1.00 36.32  ? 179 ILE A CG2 1 
ATOM   1202  C CD1 . ILE A 1 179 ? 10.794  -13.638 -23.132 1.00 38.85  ? 179 ILE A CD1 1 
ATOM   1203  N N   . ALA A 1 180 ? 9.360   -18.366 -24.505 1.00 30.77  ? 180 ALA A N   1 
ATOM   1204  C CA  . ALA A 1 180 ? 8.882   -18.768 -25.823 1.00 29.24  ? 180 ALA A CA  1 
ATOM   1205  C C   . ALA A 1 180 ? 7.383   -18.552 -25.977 1.00 32.37  ? 180 ALA A C   1 
ATOM   1206  O O   . ALA A 1 180 ? 6.935   -18.085 -27.031 1.00 34.82  ? 180 ALA A O   1 
ATOM   1207  C CB  . ALA A 1 180 ? 9.247   -20.227 -26.102 1.00 27.68  ? 180 ALA A CB  1 
ATOM   1208  N N   . GLU A 1 181 ? 6.593   -18.872 -24.944 1.00 32.15  ? 181 GLU A N   1 
ATOM   1209  C CA  . GLU A 1 181 ? 5.144   -18.956 -25.112 1.00 32.34  ? 181 GLU A CA  1 
ATOM   1210  C C   . GLU A 1 181 ? 4.555   -17.625 -25.551 1.00 29.62  ? 181 GLU A C   1 
ATOM   1211  O O   . GLU A 1 181 ? 3.878   -17.535 -26.578 1.00 31.05  ? 181 GLU A O   1 
ATOM   1212  C CB  . GLU A 1 181 ? 4.474   -19.432 -23.822 1.00 35.99  ? 181 GLU A CB  1 
ATOM   1213  C CG  . GLU A 1 181 ? 3.056   -19.991 -24.053 1.00 40.68  ? 181 GLU A CG  1 
ATOM   1214  C CD  . GLU A 1 181 ? 2.340   -20.403 -22.753 1.00 56.97  ? 181 GLU A CD  1 
ATOM   1215  O OE1 . GLU A 1 181 ? 2.943   -21.149 -21.936 1.00 50.74  ? 181 GLU A OE1 1 
ATOM   1216  O OE2 . GLU A 1 181 ? 1.167   -19.989 -22.553 1.00 54.05  ? 181 GLU A OE2 1 
ATOM   1217  N N   . THR A 1 182 ? 4.785   -16.582 -24.779 1.00 30.57  ? 182 THR A N   1 
ATOM   1218  C CA  . THR A 1 182 ? 4.184   -15.293 -25.070 1.00 33.33  ? 182 THR A CA  1 
ATOM   1219  C C   . THR A 1 182 ? 5.194   -14.266 -25.524 1.00 28.00  ? 182 THR A C   1 
ATOM   1220  O O   . THR A 1 182 ? 4.793   -13.173 -25.928 1.00 31.10  ? 182 THR A O   1 
ATOM   1221  C CB  . THR A 1 182 ? 3.459   -14.740 -23.834 1.00 31.96  ? 182 THR A CB  1 
ATOM   1222  O OG1 . THR A 1 182 ? 4.432   -14.470 -22.819 1.00 32.82  ? 182 THR A OG1 1 
ATOM   1223  C CG2 . THR A 1 182 ? 2.433   -15.741 -23.313 1.00 29.91  ? 182 THR A CG2 1 
ATOM   1224  N N   . GLY A 1 183 ? 6.483   -14.575 -25.451 1.00 32.30  ? 183 GLY A N   1 
ATOM   1225  C CA  . GLY A 1 183 ? 7.487   -13.567 -25.692 1.00 33.03  ? 183 GLY A CA  1 
ATOM   1226  C C   . GLY A 1 183 ? 7.746   -12.651 -24.525 1.00 36.85  ? 183 GLY A C   1 
ATOM   1227  O O   . GLY A 1 183 ? 8.462   -11.654 -24.701 1.00 33.99  ? 183 GLY A O   1 
ATOM   1228  N N   . MET A 1 184 ? 7.206   -12.972 -23.337 1.00 36.79  ? 184 MET A N   1 
ATOM   1229  C CA  . MET A 1 184 ? 7.266   -12.113 -22.157 1.00 36.02  ? 184 MET A CA  1 
ATOM   1230  C C   . MET A 1 184 ? 7.333   -12.956 -20.886 1.00 31.49  ? 184 MET A C   1 
ATOM   1231  O O   . MET A 1 184 ? 6.622   -13.950 -20.740 1.00 30.68  ? 184 MET A O   1 
ATOM   1232  C CB  . MET A 1 184 ? 6.054   -11.180 -22.057 1.00 30.92  ? 184 MET A CB  1 
ATOM   1233  C CG  . MET A 1 184 ? 5.794   -10.308 -23.254 1.00 36.40  ? 184 MET A CG  1 
ATOM   1234  S SD  . MET A 1 184 ? 4.274   -9.355  -23.021 1.00 38.97  ? 184 MET A SD  1 
ATOM   1235  C CE  . MET A 1 184 ? 3.049   -10.662 -23.055 1.00 37.86  ? 184 MET A CE  1 
ATOM   1236  N N   . VAL A 1 185 ? 8.185   -12.531 -19.961 1.00 34.94  ? 185 VAL A N   1 
ATOM   1237  C CA  . VAL A 1 185 ? 8.438   -13.229 -18.710 1.00 29.72  ? 185 VAL A CA  1 
ATOM   1238  C C   . VAL A 1 185 ? 8.498   -12.162 -17.631 1.00 34.85  ? 185 VAL A C   1 
ATOM   1239  O O   . VAL A 1 185 ? 8.818   -11.003 -17.906 1.00 31.45  ? 185 VAL A O   1 
ATOM   1240  C CB  . VAL A 1 185 ? 9.750   -14.053 -18.763 1.00 27.78  ? 185 VAL A CB  1 
ATOM   1241  C CG1 . VAL A 1 185 ? 10.105  -14.628 -17.407 1.00 27.10  ? 185 VAL A CG1 1 
ATOM   1242  C CG2 . VAL A 1 185 ? 9.636   -15.172 -19.759 1.00 31.28  ? 185 VAL A CG2 1 
ATOM   1243  N N   . ILE A 1 186 ? 8.163   -12.540 -16.400 1.00 34.62  ? 186 ILE A N   1 
ATOM   1244  C CA  . ILE A 1 186 ? 8.336   -11.646 -15.263 1.00 35.11  ? 186 ILE A CA  1 
ATOM   1245  C C   . ILE A 1 186 ? 9.108   -12.385 -14.181 1.00 25.07  ? 186 ILE A C   1 
ATOM   1246  O O   . ILE A 1 186 ? 8.886   -13.578 -13.957 1.00 28.66  ? 186 ILE A O   1 
ATOM   1247  C CB  . ILE A 1 186 ? 6.989   -11.106 -14.736 1.00 32.36  ? 186 ILE A CB  1 
ATOM   1248  C CG1 . ILE A 1 186 ? 7.233   -10.075 -13.633 1.00 32.87  ? 186 ILE A CG1 1 
ATOM   1249  C CG2 . ILE A 1 186 ? 6.076   -12.242 -14.262 1.00 31.41  ? 186 ILE A CG2 1 
ATOM   1250  C CD1 . ILE A 1 186 ? 5.960   -9.585  -12.984 1.00 38.07  ? 186 ILE A CD1 1 
ATOM   1251  N N   . ALA A 1 187 ? 10.079  -11.700 -13.583 1.00 27.30  ? 187 ALA A N   1 
ATOM   1252  C CA  . ALA A 1 187 ? 10.853  -12.211 -12.458 1.00 29.31  ? 187 ALA A CA  1 
ATOM   1253  C C   . ALA A 1 187 ? 10.533  -11.368 -11.232 1.00 31.52  ? 187 ALA A C   1 
ATOM   1254  O O   . ALA A 1 187 ? 10.446  -10.138 -11.320 1.00 31.48  ? 187 ALA A O   1 
ATOM   1255  C CB  . ALA A 1 187 ? 12.360  -12.180 -12.730 1.00 27.18  ? 187 ALA A CB  1 
ATOM   1256  N N   . LYS A 1 188 ? 10.321  -12.031 -10.098 1.00 27.61  ? 188 LYS A N   1 
ATOM   1257  C CA  . LYS A 1 188 ? 9.743   -11.367 -8.939  1.00 35.06  ? 188 LYS A CA  1 
ATOM   1258  C C   . LYS A 1 188 ? 10.541  -11.683 -7.690  1.00 32.11  ? 188 LYS A C   1 
ATOM   1259  O O   . LYS A 1 188 ? 10.864  -12.848 -7.431  1.00 30.25  ? 188 LYS A O   1 
ATOM   1260  C CB  . LYS A 1 188 ? 8.279   -11.772 -8.726  1.00 29.56  ? 188 LYS A CB  1 
ATOM   1261  C CG  . LYS A 1 188 ? 7.465   -11.935 -9.992  1.00 32.74  ? 188 LYS A CG  1 
ATOM   1262  C CD  . LYS A 1 188 ? 6.022   -11.576 -9.745  1.00 38.36  ? 188 LYS A CD  1 
ATOM   1263  C CE  . LYS A 1 188 ? 5.098   -12.363 -10.655 1.00 32.41  ? 188 LYS A CE  1 
ATOM   1264  N NZ  . LYS A 1 188 ? 3.694   -12.359 -10.145 1.00 43.80  ? 188 LYS A NZ  1 
ATOM   1265  N N   . GLN A 1 189 ? 10.861  -10.629 -6.939  1.00 34.15  ? 189 GLN A N   1 
ATOM   1266  C CA  . GLN A 1 189 ? 11.272  -10.745 -5.552  1.00 37.84  ? 189 GLN A CA  1 
ATOM   1267  C C   . GLN A 1 189 ? 10.388  -11.756 -4.832  1.00 33.53  ? 189 GLN A C   1 
ATOM   1268  O O   . GLN A 1 189 ? 9.188   -11.841 -5.092  1.00 33.29  ? 189 GLN A O   1 
ATOM   1269  C CB  . GLN A 1 189 ? 11.156  -9.374  -4.881  1.00 33.89  ? 189 GLN A CB  1 
ATOM   1270  C CG  . GLN A 1 189 ? 12.362  -8.959  -4.072  1.00 45.85  ? 189 GLN A CG  1 
ATOM   1271  C CD  . GLN A 1 189 ? 12.223  -7.552  -3.530  1.00 53.06  ? 189 GLN A CD  1 
ATOM   1272  O OE1 . GLN A 1 189 ? 11.201  -6.895  -3.744  1.00 57.28  ? 189 GLN A OE1 1 
ATOM   1273  N NE2 . GLN A 1 189 ? 13.253  -7.077  -2.826  1.00 51.53  ? 189 GLN A NE2 1 
ATOM   1274  N N   . ASP A 1 190 ? 10.983  -12.531 -3.928  1.00 31.20  ? 190 ASP A N   1 
ATOM   1275  C CA  . ASP A 1 190 ? 10.206  -13.554 -3.236  1.00 35.86  ? 190 ASP A CA  1 
ATOM   1276  C C   . ASP A 1 190 ? 9.333   -12.977 -2.127  1.00 36.13  ? 190 ASP A C   1 
ATOM   1277  O O   . ASP A 1 190 ? 8.278   -13.547 -1.828  1.00 38.17  ? 190 ASP A O   1 
ATOM   1278  C CB  . ASP A 1 190 ? 11.129  -14.636 -2.667  1.00 34.81  ? 190 ASP A CB  1 
ATOM   1279  C CG  . ASP A 1 190 ? 10.433  -16.002 -2.530  1.00 31.52  ? 190 ASP A CG  1 
ATOM   1280  O OD1 . ASP A 1 190 ? 9.330   -16.212 -3.084  1.00 26.46  ? 190 ASP A OD1 1 
ATOM   1281  O OD2 . ASP A 1 190 ? 10.999  -16.880 -1.858  1.00 36.86  ? 190 ASP A OD2 1 
ATOM   1282  N N   . ARG A 1 191 ? 9.740   -11.866 -1.515  1.00 34.43  ? 191 ARG A N   1 
ATOM   1283  C CA  . ARG A 1 191 ? 8.981   -11.236 -0.444  1.00 44.89  ? 191 ARG A CA  1 
ATOM   1284  C C   . ARG A 1 191 ? 8.780   -9.757  -0.747  1.00 48.15  ? 191 ARG A C   1 
ATOM   1285  O O   . ARG A 1 191 ? 9.715   -9.083  -1.188  1.00 48.08  ? 191 ARG A O   1 
ATOM   1286  C CB  . ARG A 1 191 ? 9.695   -11.376 0.918   1.00 43.74  ? 191 ARG A CB  1 
ATOM   1287  C CG  . ARG A 1 191 ? 9.347   -12.619 1.739   1.00 44.52  ? 191 ARG A CG  1 
ATOM   1288  C CD  . ARG A 1 191 ? 9.799   -12.446 3.205   1.00 52.02  ? 191 ARG A CD  1 
ATOM   1289  N NE  . ARG A 1 191 ? 9.701   -13.652 4.026   1.00 42.86  ? 191 ARG A NE  1 
ATOM   1290  C CZ  . ARG A 1 191 ? 10.693  -14.509 4.224   1.00 45.74  ? 191 ARG A CZ  1 
ATOM   1291  N NH1 . ARG A 1 191 ? 11.867  -14.368 3.621   1.00 40.05  ? 191 ARG A NH1 1 
ATOM   1292  N NH2 . ARG A 1 191 ? 10.511  -15.529 5.059   1.00 49.94  ? 191 ARG A NH2 1 
ATOM   1293  N N   . SER A 1 192 ? 7.543   -9.279  -0.536  1.00 49.92  ? 192 SER A N   1 
ATOM   1294  C CA  . SER A 1 192 ? 7.165   -7.872  -0.347  1.00 52.82  ? 192 SER A CA  1 
ATOM   1295  C C   . SER A 1 192 ? 5.685   -7.693  -0.658  1.00 59.21  ? 192 SER A C   1 
ATOM   1296  O O   . SER A 1 192 ? 4.864   -8.549  -0.302  1.00 58.23  ? 192 SER A O   1 
ATOM   1297  C CB  . SER A 1 192 ? 7.973   -6.900  -1.213  1.00 59.33  ? 192 SER A CB  1 
ATOM   1298  O OG  . SER A 1 192 ? 8.029   -5.614  -0.612  1.00 62.96  ? 192 SER A OG  1 
ATOM   1299  N N   . GLY A 1 193 ? 5.341   -6.588  -1.328  1.00 61.75  ? 193 GLY A N   1 
ATOM   1300  C CA  . GLY A 1 193 ? 3.961   -6.283  -1.664  1.00 67.53  ? 193 GLY A CA  1 
ATOM   1301  C C   . GLY A 1 193 ? 3.753   -5.167  -2.675  1.00 70.48  ? 193 GLY A C   1 
ATOM   1302  O O   . GLY A 1 193 ? 3.228   -4.097  -2.330  1.00 65.28  ? 193 GLY A O   1 
ATOM   1303  N N   . GLY A 1 194 ? 4.156   -5.407  -3.921  1.00 73.26  ? 194 GLY A N   1 
ATOM   1304  C CA  . GLY A 1 194 ? 3.924   -4.444  -4.984  1.00 75.15  ? 194 GLY A CA  1 
ATOM   1305  C C   . GLY A 1 194 ? 4.770   -4.744  -6.201  1.00 68.60  ? 194 GLY A C   1 
ATOM   1306  O O   . GLY A 1 194 ? 5.711   -5.545  -6.165  1.00 62.95  ? 194 GLY A O   1 
ATOM   1307  N N   . GLY A 1 195 ? 4.425   -4.063  -7.293  1.00 63.19  ? 195 GLY A N   1 
ATOM   1308  C CA  . GLY A 1 195 ? 5.167   -4.190  -8.530  1.00 63.11  ? 195 GLY A CA  1 
ATOM   1309  C C   . GLY A 1 195 ? 6.455   -3.388  -8.578  1.00 60.66  ? 195 GLY A C   1 
ATOM   1310  O O   . GLY A 1 195 ? 6.917   -3.024  -9.661  1.00 62.12  ? 195 GLY A O   1 
ATOM   1311  N N   . HIS A 1 196 ? 7.048   -3.092  -7.422  1.00 61.78  ? 196 HIS A N   1 
ATOM   1312  C CA  . HIS A 1 196 ? 8.353   -2.443  -7.420  1.00 65.29  ? 196 HIS A CA  1 
ATOM   1313  C C   . HIS A 1 196 ? 9.472   -3.464  -7.621  1.00 65.68  ? 196 HIS A C   1 
ATOM   1314  O O   . HIS A 1 196 ? 10.312  -3.296  -8.511  1.00 63.04  ? 196 HIS A O   1 
ATOM   1315  C CB  . HIS A 1 196 ? 8.555   -1.662  -6.116  1.00 68.00  ? 196 HIS A CB  1 
ATOM   1316  C CG  . HIS A 1 196 ? 9.884   -0.971  -6.013  1.00 73.82  ? 196 HIS A CG  1 
ATOM   1317  N ND1 . HIS A 1 196 ? 10.799  -0.938  -7.044  1.00 76.29  ? 196 HIS A ND1 1 
ATOM   1318  C CD2 . HIS A 1 196 ? 10.449  -0.284  -4.991  1.00 78.91  ? 196 HIS A CD2 1 
ATOM   1319  C CE1 . HIS A 1 196 ? 11.870  -0.264  -6.662  1.00 78.19  ? 196 HIS A CE1 1 
ATOM   1320  N NE2 . HIS A 1 196 ? 11.683  0.144   -5.420  1.00 80.96  ? 196 HIS A NE2 1 
ATOM   1321  N N   . GLY A 1 197 ? 9.486   -4.532  -6.821  1.00 62.79  ? 197 GLY A N   1 
ATOM   1322  C CA  . GLY A 1 197 ? 10.504  -5.559  -6.950  1.00 56.79  ? 197 GLY A CA  1 
ATOM   1323  C C   . GLY A 1 197 ? 10.150  -6.669  -7.926  1.00 48.27  ? 197 GLY A C   1 
ATOM   1324  O O   . GLY A 1 197 ? 10.282  -7.851  -7.592  1.00 41.65  ? 197 GLY A O   1 
ATOM   1325  N N   . ASN A 1 198 ? 9.665   -6.305  -9.116  1.00 47.10  ? 198 ASN A N   1 
ATOM   1326  C CA  . ASN A 1 198 ? 9.483   -7.228  -10.233 1.00 47.69  ? 198 ASN A CA  1 
ATOM   1327  C C   . ASN A 1 198 ? 10.070  -6.597  -11.488 1.00 44.34  ? 198 ASN A C   1 
ATOM   1328  O O   . ASN A 1 198 ? 10.025  -5.378  -11.660 1.00 47.97  ? 198 ASN A O   1 
ATOM   1329  C CB  . ASN A 1 198 ? 8.000   -7.579  -10.507 1.00 42.66  ? 198 ASN A CB  1 
ATOM   1330  C CG  . ASN A 1 198 ? 7.217   -7.915  -9.247  1.00 42.36  ? 198 ASN A CG  1 
ATOM   1331  O OD1 . ASN A 1 198 ? 7.694   -8.628  -8.369  1.00 50.13  ? 198 ASN A OD1 1 
ATOM   1332  N ND2 . ASN A 1 198 ? 6.001   -7.391  -9.160  1.00 50.64  ? 198 ASN A ND2 1 
ATOM   1333  N N   . ILE A 1 199 ? 10.615  -7.424  -12.374 1.00 39.22  ? 199 ILE A N   1 
ATOM   1334  C CA  . ILE A 1 199 ? 11.260  -6.930  -13.587 1.00 41.19  ? 199 ILE A CA  1 
ATOM   1335  C C   . ILE A 1 199 ? 10.743  -7.709  -14.788 1.00 37.42  ? 199 ILE A C   1 
ATOM   1336  O O   . ILE A 1 199 ? 10.760  -8.945  -14.791 1.00 38.25  ? 199 ILE A O   1 
ATOM   1337  C CB  . ILE A 1 199 ? 12.792  -7.046  -13.512 1.00 43.16  ? 199 ILE A CB  1 
ATOM   1338  C CG1 . ILE A 1 199 ? 13.345  -6.291  -12.310 1.00 39.76  ? 199 ILE A CG1 1 
ATOM   1339  C CG2 . ILE A 1 199 ? 13.432  -6.529  -14.797 1.00 40.46  ? 199 ILE A CG2 1 
ATOM   1340  C CD1 . ILE A 1 199 ? 14.755  -6.709  -11.967 1.00 40.57  ? 199 ILE A CD1 1 
ATOM   1341  N N   . GLY A 1 200 ? 10.306  -6.997  -15.813 1.00 39.15  ? 200 GLY A N   1 
ATOM   1342  C CA  . GLY A 1 200 ? 9.860   -7.659  -17.018 1.00 40.84  ? 200 GLY A CA  1 
ATOM   1343  C C   . GLY A 1 200 ? 11.007  -8.005  -17.952 1.00 39.40  ? 200 GLY A C   1 
ATOM   1344  O O   . GLY A 1 200 ? 12.053  -7.351  -17.982 1.00 37.07  ? 200 GLY A O   1 
ATOM   1345  N N   . ILE A 1 201 ? 10.809  -9.076  -18.711 1.00 33.50  ? 201 ILE A N   1 
ATOM   1346  C CA  . ILE A 1 201 ? 11.682  -9.418  -19.824 1.00 34.50  ? 201 ILE A CA  1 
ATOM   1347  C C   . ILE A 1 201 ? 10.811  -9.610  -21.051 1.00 38.57  ? 201 ILE A C   1 
ATOM   1348  O O   . ILE A 1 201 ? 9.823   -10.354 -21.009 1.00 33.53  ? 201 ILE A O   1 
ATOM   1349  C CB  . ILE A 1 201 ? 12.529  -10.672 -19.542 1.00 36.54  ? 201 ILE A CB  1 
ATOM   1350  C CG1 . ILE A 1 201 ? 13.397  -10.451 -18.292 1.00 41.68  ? 201 ILE A CG1 1 
ATOM   1351  C CG2 . ILE A 1 201 ? 13.413  -10.969 -20.719 1.00 37.69  ? 201 ILE A CG2 1 
ATOM   1352  C CD1 . ILE A 1 201 ? 12.957  -11.235 -17.055 1.00 34.57  ? 201 ILE A CD1 1 
ATOM   1353  N N   . SER A 1 202 ? 11.174  -8.937  -22.142 1.00 42.41  ? 202 SER A N   1 
ATOM   1354  C CA  . SER A 1 202 ? 10.344  -8.904  -23.336 1.00 39.25  ? 202 SER A CA  1 
ATOM   1355  C C   . SER A 1 202 ? 11.154  -9.237  -24.584 1.00 44.67  ? 202 SER A C   1 
ATOM   1356  O O   . SER A 1 202 ? 12.319  -8.842  -24.729 1.00 45.93  ? 202 SER A O   1 
ATOM   1357  C CB  . SER A 1 202 ? 9.687   -7.547  -23.505 1.00 35.64  ? 202 SER A CB  1 
ATOM   1358  O OG  . SER A 1 202 ? 8.582   -7.654  -24.372 1.00 50.06  ? 202 SER A OG  1 
ATOM   1359  N N   . THR A 1 203 ? 10.500  -9.965  -25.488 1.00 44.24  ? 203 THR A N   1 
ATOM   1360  C CA  . THR A 1 203 ? 11.030  -10.229 -26.818 1.00 43.74  ? 203 THR A CA  1 
ATOM   1361  C C   . THR A 1 203 ? 10.800  -9.047  -27.752 1.00 45.41  ? 203 THR A C   1 
ATOM   1362  O O   . THR A 1 203 ? 11.665  -8.713  -28.569 1.00 50.30  ? 203 THR A O   1 
ATOM   1363  C CB  . THR A 1 203 ? 10.372  -11.488 -27.399 1.00 44.51  ? 203 THR A CB  1 
ATOM   1364  O OG1 . THR A 1 203 ? 11.185  -12.639 -27.125 1.00 45.50  ? 203 THR A OG1 1 
ATOM   1365  C CG2 . THR A 1 203 ? 10.202  -11.357 -28.883 1.00 42.13  ? 203 THR A CG2 1 
ATOM   1366  N N   . SER A 1 204 ? 9.647   -8.405  -27.645 1.00 49.78  ? 204 SER A N   1 
ATOM   1367  C CA  . SER A 1 204 ? 9.337   -7.303  -28.536 1.00 55.05  ? 204 SER A CA  1 
ATOM   1368  C C   . SER A 1 204 ? 10.099  -6.046  -28.123 1.00 60.26  ? 204 SER A C   1 
ATOM   1369  O O   . SER A 1 204 ? 10.316  -5.805  -26.934 1.00 57.96  ? 204 SER A O   1 
ATOM   1370  C CB  . SER A 1 204 ? 7.841   -7.018  -28.537 1.00 51.97  ? 204 SER A CB  1 
ATOM   1371  O OG  . SER A 1 204 ? 7.610   -5.626  -28.616 1.00 60.24  ? 204 SER A OG  1 
ATOM   1372  N N   . PRO A 1 205 ? 10.507  -5.216  -29.101 1.00 64.59  ? 205 PRO A N   1 
ATOM   1373  C CA  . PRO A 1 205 ? 11.155  -3.931  -28.775 1.00 69.20  ? 205 PRO A CA  1 
ATOM   1374  C C   . PRO A 1 205 ? 10.242  -2.958  -28.031 1.00 66.16  ? 205 PRO A C   1 
ATOM   1375  O O   . PRO A 1 205 ? 10.627  -1.818  -27.749 1.00 63.95  ? 205 PRO A O   1 
ATOM   1376  C CB  . PRO A 1 205 ? 11.563  -3.376  -30.152 1.00 68.46  ? 205 PRO A CB  1 
ATOM   1377  C CG  . PRO A 1 205 ? 11.496  -4.550  -31.105 1.00 66.34  ? 205 PRO A CG  1 
ATOM   1378  C CD  . PRO A 1 205 ? 10.466  -5.486  -30.552 1.00 61.02  ? 205 PRO A CD  1 
ATOM   1379  N N   . GLU A 1 206 ? 9.028   -3.401  -27.720 1.00 68.18  ? 206 GLU A N   1 
ATOM   1380  C CA  . GLU A 1 206 ? 8.100   -2.682  -26.868 1.00 66.66  ? 206 GLU A CA  1 
ATOM   1381  C C   . GLU A 1 206 ? 8.248   -3.180  -25.431 1.00 70.22  ? 206 GLU A C   1 
ATOM   1382  O O   . GLU A 1 206 ? 9.095   -4.024  -25.120 1.00 69.58  ? 206 GLU A O   1 
ATOM   1383  C CB  . GLU A 1 206 ? 6.672   -2.877  -27.383 1.00 66.38  ? 206 GLU A CB  1 
ATOM   1384  C CG  . GLU A 1 206 ? 5.645   -1.851  -26.922 1.00 74.22  ? 206 GLU A CG  1 
ATOM   1385  C CD  . GLU A 1 206 ? 4.727   -2.387  -25.819 1.00 68.97  ? 206 GLU A CD  1 
ATOM   1386  O OE1 . GLU A 1 206 ? 4.609   -3.627  -25.681 1.00 64.57  ? 206 GLU A OE1 1 
ATOM   1387  O OE2 . GLU A 1 206 ? 4.120   -1.564  -25.096 1.00 71.15  ? 206 GLU A OE2 1 
ATOM   1388  N N   . SER A 1 207 ? 7.405   -2.653  -24.543 1.00 71.77  ? 207 SER A N   1 
ATOM   1389  C CA  . SER A 1 207 ? 7.317   -3.140  -23.168 1.00 65.91  ? 207 SER A CA  1 
ATOM   1390  C C   . SER A 1 207 ? 6.048   -2.573  -22.543 1.00 69.25  ? 207 SER A C   1 
ATOM   1391  O O   . SER A 1 207 ? 5.981   -1.368  -22.274 1.00 70.98  ? 207 SER A O   1 
ATOM   1392  C CB  . SER A 1 207 ? 8.558   -2.742  -22.375 1.00 66.94  ? 207 SER A CB  1 
ATOM   1393  O OG  . SER A 1 207 ? 9.028   -1.453  -22.741 1.00 73.89  ? 207 SER A OG  1 
ATOM   1394  N N   . SER A 1 208 ? 5.041   -3.436  -22.314 1.00 63.72  ? 208 SER A N   1 
ATOM   1395  C CA  . SER A 1 208 ? 3.770   -3.035  -21.692 1.00 64.19  ? 208 SER A CA  1 
ATOM   1396  C C   . SER A 1 208 ? 3.482   -3.970  -20.514 1.00 57.90  ? 208 SER A C   1 
ATOM   1397  O O   . SER A 1 208 ? 2.627   -4.851  -20.607 1.00 56.80  ? 208 SER A O   1 
ATOM   1398  C CB  . SER A 1 208 ? 2.632   -3.055  -22.717 1.00 68.98  ? 208 SER A CB  1 
ATOM   1399  O OG  . SER A 1 208 ? 1.401   -2.667  -22.129 1.00 60.84  ? 208 SER A OG  1 
ATOM   1400  N N   . PHE A 1 209 ? 4.180   -3.767  -19.400 1.00 52.21  ? 209 PHE A N   1 
ATOM   1401  C CA  . PHE A 1 209 ? 4.090   -4.668  -18.248 1.00 50.44  ? 209 PHE A CA  1 
ATOM   1402  C C   . PHE A 1 209 ? 3.503   -3.963  -17.032 1.00 49.99  ? 209 PHE A C   1 
ATOM   1403  O O   . PHE A 1 209 ? 4.245   -3.300  -16.287 1.00 52.05  ? 209 PHE A O   1 
ATOM   1404  C CB  . PHE A 1 209 ? 5.471   -5.223  -17.901 1.00 50.89  ? 209 PHE A CB  1 
ATOM   1405  C CG  . PHE A 1 209 ? 5.961   -6.315  -18.816 1.00 49.62  ? 209 PHE A CG  1 
ATOM   1406  C CD1 . PHE A 1 209 ? 6.305   -6.040  -20.129 1.00 53.21  ? 209 PHE A CD1 1 
ATOM   1407  C CD2 . PHE A 1 209 ? 6.143   -7.602  -18.340 1.00 45.58  ? 209 PHE A CD2 1 
ATOM   1408  C CE1 . PHE A 1 209 ? 6.781   -7.035  -20.956 1.00 48.59  ? 209 PHE A CE1 1 
ATOM   1409  C CE2 . PHE A 1 209 ? 6.621   -8.594  -19.165 1.00 43.04  ? 209 PHE A CE2 1 
ATOM   1410  C CZ  . PHE A 1 209 ? 6.938   -8.311  -20.470 1.00 38.93  ? 209 PHE A CZ  1 
ATOM   1411  N N   . PRO A 1 210 ? 2.196   -4.074  -16.780 1.00 54.08  ? 210 PRO A N   1 
ATOM   1412  C CA  . PRO A 1 210 ? 1.639   -3.580  -15.507 1.00 51.58  ? 210 PRO A CA  1 
ATOM   1413  C C   . PRO A 1 210 ? 2.231   -4.301  -14.300 1.00 52.12  ? 210 PRO A C   1 
ATOM   1414  O O   . PRO A 1 210 ? 2.259   -5.533  -14.243 1.00 52.22  ? 210 PRO A O   1 
ATOM   1415  C CB  . PRO A 1 210 ? 0.139   -3.869  -15.641 1.00 50.49  ? 210 PRO A CB  1 
ATOM   1416  C CG  . PRO A 1 210 ? -0.117  -3.907  -17.101 1.00 47.79  ? 210 PRO A CG  1 
ATOM   1417  C CD  . PRO A 1 210 ? 1.143   -4.403  -17.758 1.00 49.67  ? 210 PRO A CD  1 
ATOM   1418  N N   . GLY A 1 211 ? 2.691   -3.524  -13.321 1.00 54.21  ? 211 GLY A N   1 
ATOM   1419  C CA  . GLY A 1 211 ? 3.211   -4.105  -12.094 1.00 56.05  ? 211 GLY A CA  1 
ATOM   1420  C C   . GLY A 1 211 ? 4.631   -4.635  -12.195 1.00 56.07  ? 211 GLY A C   1 
ATOM   1421  O O   . GLY A 1 211 ? 4.924   -5.764  -11.778 1.00 49.06  ? 211 GLY A O   1 
ATOM   1422  N N   . THR A 1 212 ? 5.513   -3.814  -12.764 1.00 55.73  ? 212 THR A N   1 
ATOM   1423  C CA  . THR A 1 212 ? 6.943   -4.076  -12.839 1.00 50.79  ? 212 THR A CA  1 
ATOM   1424  C C   . THR A 1 212 ? 7.658   -2.739  -12.764 1.00 53.18  ? 212 THR A C   1 
ATOM   1425  O O   . THR A 1 212 ? 7.135   -1.732  -13.240 1.00 51.16  ? 212 THR A O   1 
ATOM   1426  C CB  . THR A 1 212 ? 7.326   -4.778  -14.139 1.00 47.34  ? 212 THR A CB  1 
ATOM   1427  O OG1 . THR A 1 212 ? 6.506   -4.270  -15.191 1.00 49.59  ? 212 THR A OG1 1 
ATOM   1428  C CG2 . THR A 1 212 ? 7.144   -6.285  -14.032 1.00 46.22  ? 212 THR A CG2 1 
ATOM   1429  N N   . ARG A 1 213 ? 8.863   -2.735  -12.169 1.00 56.59  ? 213 ARG A N   1 
ATOM   1430  C CA  . ARG A 1 213 ? 9.659   -1.507  -12.123 1.00 53.74  ? 213 ARG A CA  1 
ATOM   1431  C C   . ARG A 1 213 ? 10.323  -1.209  -13.454 1.00 49.23  ? 213 ARG A C   1 
ATOM   1432  O O   . ARG A 1 213 ? 10.521  -0.039  -13.786 1.00 52.08  ? 213 ARG A O   1 
ATOM   1433  C CB  . ARG A 1 213 ? 10.734  -1.568  -11.034 1.00 55.57  ? 213 ARG A CB  1 
ATOM   1434  C CG  . ARG A 1 213 ? 11.857  -2.581  -11.259 1.00 54.49  ? 213 ARG A CG  1 
ATOM   1435  C CD  . ARG A 1 213 ? 12.872  -2.512  -10.113 1.00 58.60  ? 213 ARG A CD  1 
ATOM   1436  N NE  . ARG A 1 213 ? 13.806  -3.632  -10.096 1.00 55.51  ? 213 ARG A NE  1 
ATOM   1437  C CZ  . ARG A 1 213 ? 14.120  -4.297  -8.992  1.00 59.55  ? 213 ARG A CZ  1 
ATOM   1438  N NH1 . ARG A 1 213 ? 13.613  -3.958  -7.815  1.00 59.82  ? 213 ARG A NH1 1 
ATOM   1439  N NH2 . ARG A 1 213 ? 14.937  -5.345  -9.072  1.00 62.59  ? 213 ARG A NH2 1 
ATOM   1440  N N   . GLU A 1 214 ? 10.650  -2.238  -14.230 1.00 49.94  ? 214 GLU A N   1 
ATOM   1441  C CA  . GLU A 1 214 ? 11.327  -2.058  -15.503 1.00 46.94  ? 214 GLU A CA  1 
ATOM   1442  C C   . GLU A 1 214 ? 11.155  -3.309  -16.342 1.00 46.34  ? 214 GLU A C   1 
ATOM   1443  O O   . GLU A 1 214 ? 10.890  -4.397  -15.823 1.00 45.15  ? 214 GLU A O   1 
ATOM   1444  C CB  . GLU A 1 214 ? 12.818  -1.761  -15.320 1.00 43.46  ? 214 GLU A CB  1 
ATOM   1445  C CG  . GLU A 1 214 ? 13.563  -2.773  -14.486 1.00 48.05  ? 214 GLU A CG  1 
ATOM   1446  C CD  . GLU A 1 214 ? 15.016  -2.389  -14.317 1.00 50.40  ? 214 GLU A CD  1 
ATOM   1447  O OE1 . GLU A 1 214 ? 15.597  -1.869  -15.290 1.00 50.33  ? 214 GLU A OE1 1 
ATOM   1448  O OE2 . GLU A 1 214 ? 15.567  -2.587  -13.212 1.00 54.40  ? 214 GLU A OE2 1 
ATOM   1449  N N   . VAL A 1 215 ? 11.327  -3.139  -17.653 1.00 47.84  ? 215 VAL A N   1 
ATOM   1450  C CA  . VAL A 1 215 ? 11.350  -4.244  -18.601 1.00 43.39  ? 215 VAL A CA  1 
ATOM   1451  C C   . VAL A 1 215 ? 12.673  -4.210  -19.352 1.00 38.43  ? 215 VAL A C   1 
ATOM   1452  O O   . VAL A 1 215 ? 13.139  -3.140  -19.751 1.00 38.97  ? 215 VAL A O   1 
ATOM   1453  C CB  . VAL A 1 215 ? 10.157  -4.187  -19.572 1.00 42.14  ? 215 VAL A CB  1 
ATOM   1454  C CG1 . VAL A 1 215 ? 10.153  -5.397  -20.480 1.00 41.33  ? 215 VAL A CG1 1 
ATOM   1455  C CG2 . VAL A 1 215 ? 8.882   -4.149  -18.802 1.00 47.96  ? 215 VAL A CG2 1 
ATOM   1456  N N   . LEU A 1 216 ? 13.291  -5.379  -19.509 1.00 41.32  ? 216 LEU A N   1 
ATOM   1457  C CA  . LEU A 1 216 ? 14.555  -5.544  -20.210 1.00 39.10  ? 216 LEU A CA  1 
ATOM   1458  C C   . LEU A 1 216 ? 14.311  -6.339  -21.485 1.00 41.58  ? 216 LEU A C   1 
ATOM   1459  O O   . LEU A 1 216 ? 13.308  -7.043  -21.617 1.00 43.23  ? 216 LEU A O   1 
ATOM   1460  C CB  . LEU A 1 216 ? 15.596  -6.266  -19.337 1.00 33.94  ? 216 LEU A CB  1 
ATOM   1461  C CG  . LEU A 1 216 ? 15.699  -5.911  -17.845 1.00 40.09  ? 216 LEU A CG  1 
ATOM   1462  C CD1 . LEU A 1 216 ? 16.829  -6.674  -17.155 1.00 40.68  ? 216 LEU A CD1 1 
ATOM   1463  C CD2 . LEU A 1 216 ? 15.851  -4.412  -17.618 1.00 35.66  ? 216 LEU A CD2 1 
ATOM   1464  N N   . ALA A 1 217 ? 15.243  -6.228  -22.431 1.00 45.15  ? 217 ALA A N   1 
ATOM   1465  C CA  . ALA A 1 217 ? 15.158  -6.979  -23.676 1.00 42.47  ? 217 ALA A CA  1 
ATOM   1466  C C   . ALA A 1 217 ? 15.809  -8.343  -23.503 1.00 41.23  ? 217 ALA A C   1 
ATOM   1467  O O   . ALA A 1 217 ? 16.924  -8.442  -22.981 1.00 34.70  ? 217 ALA A O   1 
ATOM   1468  C CB  . ALA A 1 217 ? 15.833  -6.226  -24.822 1.00 48.12  ? 217 ALA A CB  1 
ATOM   1469  N N   . TYR A 1 218 ? 15.108  -9.386  -23.941 1.00 38.62  ? 218 TYR A N   1 
ATOM   1470  C CA  . TYR A 1 218 ? 15.723  -10.701 -24.024 1.00 45.24  ? 218 TYR A CA  1 
ATOM   1471  C C   . TYR A 1 218 ? 16.861  -10.684 -25.042 1.00 44.17  ? 218 TYR A C   1 
ATOM   1472  O O   . TYR A 1 218 ? 16.885  -9.870  -25.967 1.00 44.63  ? 218 TYR A O   1 
ATOM   1473  C CB  . TYR A 1 218 ? 14.677  -11.750 -24.400 1.00 38.96  ? 218 TYR A CB  1 
ATOM   1474  C CG  . TYR A 1 218 ? 15.168  -13.177 -24.348 1.00 41.97  ? 218 TYR A CG  1 
ATOM   1475  C CD1 . TYR A 1 218 ? 15.197  -13.885 -23.153 1.00 38.66  ? 218 TYR A CD1 1 
ATOM   1476  C CD2 . TYR A 1 218 ? 15.587  -13.826 -25.499 1.00 46.27  ? 218 TYR A CD2 1 
ATOM   1477  C CE1 . TYR A 1 218 ? 15.629  -15.191 -23.111 1.00 40.83  ? 218 TYR A CE1 1 
ATOM   1478  C CE2 . TYR A 1 218 ? 16.022  -15.141 -25.460 1.00 47.42  ? 218 TYR A CE2 1 
ATOM   1479  C CZ  . TYR A 1 218 ? 16.037  -15.816 -24.264 1.00 43.69  ? 218 TYR A CZ  1 
ATOM   1480  O OH  . TYR A 1 218 ? 16.477  -17.119 -24.227 1.00 52.23  ? 218 TYR A OH  1 
ATOM   1481  N N   . ALA A 1 219 ? 17.816  -11.603 -24.856 1.00 50.77  ? 219 ALA A N   1 
ATOM   1482  C CA  . ALA A 1 219 ? 19.026  -11.646 -25.678 1.00 49.98  ? 219 ALA A CA  1 
ATOM   1483  C C   . ALA A 1 219 ? 19.635  -13.041 -25.534 1.00 51.44  ? 219 ALA A C   1 
ATOM   1484  O O   . ALA A 1 219 ? 20.288  -13.321 -24.526 1.00 53.87  ? 219 ALA A O   1 
ATOM   1485  C CB  . ALA A 1 219 ? 20.004  -10.567 -25.251 1.00 54.70  ? 219 ALA A CB  1 
ATOM   1486  N N   . ASN A 1 220 ? 19.410  -13.900 -26.535 1.00 49.75  ? 220 ASN A N   1 
ATOM   1487  C CA  . ASN A 1 220 ? 19.973  -15.252 -26.496 1.00 54.18  ? 220 ASN A CA  1 
ATOM   1488  C C   . ASN A 1 220 ? 21.480  -15.219 -26.281 1.00 59.74  ? 220 ASN A C   1 
ATOM   1489  O O   . ASN A 1 220 ? 22.033  -16.026 -25.523 1.00 58.74  ? 220 ASN A O   1 
ATOM   1490  C CB  . ASN A 1 220 ? 19.670  -16.006 -27.793 1.00 49.41  ? 220 ASN A CB  1 
ATOM   1491  C CG  . ASN A 1 220 ? 18.201  -16.294 -27.975 1.00 50.96  ? 220 ASN A CG  1 
ATOM   1492  O OD1 . ASN A 1 220 ? 17.434  -15.413 -28.366 1.00 51.26  ? 220 ASN A OD1 1 
ATOM   1493  N ND2 . ASN A 1 220 ? 17.797  -17.539 -27.712 1.00 51.51  ? 220 ASN A ND2 1 
ATOM   1494  N N   . ASP A 1 221 ? 22.159  -14.288 -26.946 1.00 59.53  ? 221 ASP A N   1 
ATOM   1495  C CA  . ASP A 1 221 ? 23.613  -14.212 -26.869 1.00 65.08  ? 221 ASP A CA  1 
ATOM   1496  C C   . ASP A 1 221 ? 24.078  -13.850 -25.462 1.00 64.99  ? 221 ASP A C   1 
ATOM   1497  O O   . ASP A 1 221 ? 25.022  -14.455 -24.936 1.00 60.97  ? 221 ASP A O   1 
ATOM   1498  C CB  . ASP A 1 221 ? 24.104  -13.185 -27.883 1.00 65.15  ? 221 ASP A CB  1 
ATOM   1499  C CG  . ASP A 1 221 ? 23.286  -11.912 -27.829 1.00 68.00  ? 221 ASP A CG  1 
ATOM   1500  O OD1 . ASP A 1 221 ? 22.041  -12.031 -27.735 1.00 62.72  ? 221 ASP A OD1 1 
ATOM   1501  O OD2 . ASP A 1 221 ? 23.875  -10.810 -27.867 1.00 72.20  ? 221 ASP A OD2 1 
ATOM   1502  N N   . GLN A 1 222 ? 23.427  -12.866 -24.839 1.00 62.92  ? 222 GLN A N   1 
ATOM   1503  C CA  . GLN A 1 222 ? 23.862  -12.327 -23.546 1.00 63.83  ? 222 GLN A CA  1 
ATOM   1504  C C   . GLN A 1 222 ? 22.975  -12.841 -22.410 1.00 63.80  ? 222 GLN A C   1 
ATOM   1505  O O   . GLN A 1 222 ? 22.375  -12.080 -21.641 1.00 55.52  ? 222 GLN A O   1 
ATOM   1506  C CB  . GLN A 1 222 ? 23.876  -10.803 -23.592 1.00 61.06  ? 222 GLN A CB  1 
ATOM   1507  C CG  . GLN A 1 222 ? 24.899  -10.221 -24.562 1.00 68.10  ? 222 GLN A CG  1 
ATOM   1508  C CD  . GLN A 1 222 ? 24.846  -8.702  -24.619 1.00 73.75  ? 222 GLN A CD  1 
ATOM   1509  O OE1 . GLN A 1 222 ? 23.790  -8.112  -24.870 1.00 73.19  ? 222 GLN A OE1 1 
ATOM   1510  N NE2 . GLN A 1 222 ? 25.988  -8.060  -24.379 1.00 67.94  ? 222 GLN A NE2 1 
ATOM   1511  N N   . LEU A 1 223 ? 22.923  -14.172 -22.296 1.00 63.14  ? 223 LEU A N   1 
ATOM   1512  C CA  . LEU A 1 223 ? 22.001  -14.804 -21.361 1.00 59.22  ? 223 LEU A CA  1 
ATOM   1513  C C   . LEU A 1 223 ? 22.503  -14.751 -19.925 1.00 60.06  ? 223 LEU A C   1 
ATOM   1514  O O   . LEU A 1 223 ? 21.700  -14.598 -18.996 1.00 55.56  ? 223 LEU A O   1 
ATOM   1515  C CB  . LEU A 1 223 ? 21.752  -16.252 -21.779 1.00 59.96  ? 223 LEU A CB  1 
ATOM   1516  C CG  . LEU A 1 223 ? 20.348  -16.816 -21.550 1.00 64.36  ? 223 LEU A CG  1 
ATOM   1517  C CD1 . LEU A 1 223 ? 19.270  -15.765 -21.814 1.00 58.49  ? 223 LEU A CD1 1 
ATOM   1518  C CD2 . LEU A 1 223 ? 20.129  -18.045 -22.434 1.00 60.57  ? 223 LEU A CD2 1 
ATOM   1519  N N   . ASP A 1 224 ? 23.812  -14.875 -19.720 1.00 58.26  ? 224 ASP A N   1 
ATOM   1520  C CA  . ASP A 1 224 ? 24.343  -14.893 -18.367 1.00 54.51  ? 224 ASP A CA  1 
ATOM   1521  C C   . ASP A 1 224 ? 24.441  -13.498 -17.772 1.00 52.39  ? 224 ASP A C   1 
ATOM   1522  O O   . ASP A 1 224 ? 24.508  -13.367 -16.545 1.00 54.18  ? 224 ASP A O   1 
ATOM   1523  C CB  . ASP A 1 224 ? 25.705  -15.586 -18.363 1.00 62.57  ? 224 ASP A CB  1 
ATOM   1524  C CG  . ASP A 1 224 ? 25.657  -16.947 -19.045 1.00 64.85  ? 224 ASP A CG  1 
ATOM   1525  O OD1 . ASP A 1 224 ? 25.135  -17.008 -20.177 1.00 68.89  ? 224 ASP A OD1 1 
ATOM   1526  O OD2 . ASP A 1 224 ? 26.127  -17.951 -18.463 1.00 64.82  ? 224 ASP A OD2 1 
ATOM   1527  N N   . THR A 1 225 ? 24.442  -12.457 -18.610 1.00 48.34  ? 225 THR A N   1 
ATOM   1528  C CA  . THR A 1 225 ? 24.377  -11.089 -18.102 1.00 48.01  ? 225 THR A CA  1 
ATOM   1529  C C   . THR A 1 225 ? 22.989  -10.757 -17.574 1.00 47.58  ? 225 THR A C   1 
ATOM   1530  O O   . THR A 1 225 ? 22.847  -10.131 -16.515 1.00 44.53  ? 225 THR A O   1 
ATOM   1531  C CB  . THR A 1 225 ? 24.759  -10.103 -19.200 1.00 48.38  ? 225 THR A CB  1 
ATOM   1532  O OG1 . THR A 1 225 ? 26.110  -10.356 -19.617 1.00 59.15  ? 225 THR A OG1 1 
ATOM   1533  C CG2 . THR A 1 225 ? 24.624  -8.673  -18.679 1.00 37.71  ? 225 THR A CG2 1 
ATOM   1534  N N   . LEU A 1 226 ? 21.955  -11.146 -18.318 1.00 42.98  ? 226 LEU A N   1 
ATOM   1535  C CA  . LEU A 1 226 ? 20.584  -10.922 -17.883 1.00 47.05  ? 226 LEU A CA  1 
ATOM   1536  C C   . LEU A 1 226 ? 20.300  -11.659 -16.574 1.00 42.20  ? 226 LEU A C   1 
ATOM   1537  O O   . LEU A 1 226 ? 19.879  -11.058 -15.581 1.00 44.06  ? 226 LEU A O   1 
ATOM   1538  C CB  . LEU A 1 226 ? 19.641  -11.377 -18.994 1.00 46.30  ? 226 LEU A CB  1 
ATOM   1539  C CG  . LEU A 1 226 ? 18.278  -10.735 -19.157 1.00 44.01  ? 226 LEU A CG  1 
ATOM   1540  C CD1 . LEU A 1 226 ? 18.399  -9.252  -18.995 1.00 43.76  ? 226 LEU A CD1 1 
ATOM   1541  C CD2 . LEU A 1 226 ? 17.783  -11.079 -20.555 1.00 47.49  ? 226 LEU A CD2 1 
ATOM   1542  N N   . ALA A 1 227 ? 20.542  -12.968 -16.555 1.00 41.62  ? 227 ALA A N   1 
ATOM   1543  C CA  . ALA A 1 227 ? 20.333  -13.749 -15.341 1.00 43.85  ? 227 ALA A CA  1 
ATOM   1544  C C   . ALA A 1 227 ? 21.048  -13.128 -14.151 1.00 41.72  ? 227 ALA A C   1 
ATOM   1545  O O   . ALA A 1 227 ? 20.488  -13.048 -13.053 1.00 43.49  ? 227 ALA A O   1 
ATOM   1546  C CB  . ALA A 1 227 ? 20.803  -15.189 -15.555 1.00 41.64  ? 227 ALA A CB  1 
ATOM   1547  N N   . ASP A 1 228 ? 22.283  -12.668 -14.347 1.00 46.01  ? 228 ASP A N   1 
ATOM   1548  C CA  . ASP A 1 228 ? 22.989  -12.014 -13.253 1.00 46.74  ? 228 ASP A CA  1 
ATOM   1549  C C   . ASP A 1 228 ? 22.258  -10.746 -12.833 1.00 42.48  ? 228 ASP A C   1 
ATOM   1550  O O   . ASP A 1 228 ? 22.010  -10.524 -11.644 1.00 43.64  ? 228 ASP A O   1 
ATOM   1551  C CB  . ASP A 1 228 ? 24.440  -11.716 -13.658 1.00 45.78  ? 228 ASP A CB  1 
ATOM   1552  C CG  . ASP A 1 228 ? 25.371  -12.910 -13.432 1.00 52.20  ? 228 ASP A CG  1 
ATOM   1553  O OD1 . ASP A 1 228 ? 25.135  -13.692 -12.479 1.00 46.12  ? 228 ASP A OD1 1 
ATOM   1554  O OD2 . ASP A 1 228 ? 26.325  -13.082 -14.227 1.00 54.89  ? 228 ASP A OD2 1 
ATOM   1555  N N   . THR A 1 229 ? 21.872  -9.915  -13.802 1.00 40.41  ? 229 THR A N   1 
ATOM   1556  C CA  . THR A 1 229 ? 21.156  -8.694  -13.459 1.00 37.31  ? 229 THR A CA  1 
ATOM   1557  C C   . THR A 1 229 ? 19.904  -9.006  -12.649 1.00 39.88  ? 229 THR A C   1 
ATOM   1558  O O   . THR A 1 229 ? 19.633  -8.365  -11.626 1.00 37.36  ? 229 THR A O   1 
ATOM   1559  C CB  . THR A 1 229 ? 20.804  -7.913  -14.723 1.00 42.76  ? 229 THR A CB  1 
ATOM   1560  O OG1 . THR A 1 229 ? 22.001  -7.633  -15.471 1.00 43.10  ? 229 THR A OG1 1 
ATOM   1561  C CG2 . THR A 1 229 ? 20.108  -6.613  -14.348 1.00 31.78  ? 229 THR A CG2 1 
ATOM   1562  N N   . LEU A 1 230 ? 19.146  -10.017 -13.069 1.00 35.71  ? 230 LEU A N   1 
ATOM   1563  C CA  . LEU A 1 230 ? 17.917  -10.318 -12.351 1.00 37.85  ? 230 LEU A CA  1 
ATOM   1564  C C   . LEU A 1 230 ? 18.201  -10.932 -10.981 1.00 40.13  ? 230 LEU A C   1 
ATOM   1565  O O   . LEU A 1 230 ? 17.461  -10.672 -10.029 1.00 36.51  ? 230 LEU A O   1 
ATOM   1566  C CB  . LEU A 1 230 ? 17.024  -11.233 -13.190 1.00 36.80  ? 230 LEU A CB  1 
ATOM   1567  C CG  . LEU A 1 230 ? 16.525  -10.606 -14.492 1.00 37.83  ? 230 LEU A CG  1 
ATOM   1568  C CD1 . LEU A 1 230 ? 16.086  -11.679 -15.435 1.00 35.27  ? 230 LEU A CD1 1 
ATOM   1569  C CD2 . LEU A 1 230 ? 15.392  -9.621  -14.246 1.00 36.92  ? 230 LEU A CD2 1 
ATOM   1570  N N   . TRP A 1 231 ? 19.272  -11.717 -10.849 1.00 40.15  ? 231 TRP A N   1 
ATOM   1571  C CA  . TRP A 1 231 ? 19.554  -12.348 -9.565  1.00 39.36  ? 231 TRP A CA  1 
ATOM   1572  C C   . TRP A 1 231 ? 19.948  -11.320 -8.507  1.00 42.31  ? 231 TRP A C   1 
ATOM   1573  O O   . TRP A 1 231 ? 19.380  -11.299 -7.408  1.00 39.41  ? 231 TRP A O   1 
ATOM   1574  C CB  . TRP A 1 231 ? 20.646  -13.409 -9.715  1.00 40.61  ? 231 TRP A CB  1 
ATOM   1575  C CG  . TRP A 1 231 ? 20.885  -14.174 -8.437  1.00 38.52  ? 231 TRP A CG  1 
ATOM   1576  C CD1 . TRP A 1 231 ? 21.997  -14.136 -7.647  1.00 36.96  ? 231 TRP A CD1 1 
ATOM   1577  C CD2 . TRP A 1 231 ? 19.972  -15.075 -7.798  1.00 37.26  ? 231 TRP A CD2 1 
ATOM   1578  N NE1 . TRP A 1 231 ? 21.839  -14.970 -6.564  1.00 33.30  ? 231 TRP A NE1 1 
ATOM   1579  C CE2 . TRP A 1 231 ? 20.600  -15.550 -6.630  1.00 37.79  ? 231 TRP A CE2 1 
ATOM   1580  C CE3 . TRP A 1 231 ? 18.689  -15.532 -8.105  1.00 36.11  ? 231 TRP A CE3 1 
ATOM   1581  C CZ2 . TRP A 1 231 ? 19.984  -16.459 -5.772  1.00 39.25  ? 231 TRP A CZ2 1 
ATOM   1582  C CZ3 . TRP A 1 231 ? 18.081  -16.429 -7.253  1.00 34.87  ? 231 TRP A CZ3 1 
ATOM   1583  C CH2 . TRP A 1 231 ? 18.725  -16.885 -6.103  1.00 32.87  ? 231 TRP A CH2 1 
ATOM   1584  N N   . SER A 1 232 ? 20.921  -10.458 -8.813  1.00 39.05  ? 232 SER A N   1 
ATOM   1585  C CA  . SER A 1 232 ? 21.410  -9.530  -7.798  1.00 38.18  ? 232 SER A CA  1 
ATOM   1586  C C   . SER A 1 232 ? 20.428  -8.403  -7.494  1.00 42.80  ? 232 SER A C   1 
ATOM   1587  O O   . SER A 1 232 ? 20.492  -7.822  -6.404  1.00 40.74  ? 232 SER A O   1 
ATOM   1588  C CB  . SER A 1 232 ? 22.757  -8.945  -8.223  1.00 45.53  ? 232 SER A CB  1 
ATOM   1589  O OG  . SER A 1 232 ? 22.606  -8.069  -9.326  1.00 46.69  ? 232 SER A OG  1 
ATOM   1590  N N   . GLN A 1 233 ? 19.522  -8.073  -8.416  1.00 42.83  ? 233 GLN A N   1 
ATOM   1591  C CA  . GLN A 1 233 ? 18.577  -7.008  -8.118  1.00 37.39  ? 233 GLN A CA  1 
ATOM   1592  C C   . GLN A 1 233 ? 17.456  -7.474  -7.199  1.00 37.87  ? 233 GLN A C   1 
ATOM   1593  O O   . GLN A 1 233 ? 16.904  -6.661  -6.453  1.00 45.98  ? 233 GLN A O   1 
ATOM   1594  C CB  . GLN A 1 233 ? 17.983  -6.445  -9.407  1.00 39.72  ? 233 GLN A CB  1 
ATOM   1595  C CG  . GLN A 1 233 ? 18.519  -5.064  -9.795  1.00 47.79  ? 233 GLN A CG  1 
ATOM   1596  C CD  . GLN A 1 233 ? 17.517  -4.247  -10.604 1.00 52.81  ? 233 GLN A CD  1 
ATOM   1597  O OE1 . GLN A 1 233 ? 17.350  -4.464  -11.801 1.00 50.67  ? 233 GLN A OE1 1 
ATOM   1598  N NE2 . GLN A 1 233 ? 16.880  -3.273  -9.959  1.00 55.11  ? 233 GLN A NE2 1 
ATOM   1599  N N   . LEU A 1 234 ? 17.117  -8.764  -7.214  1.00 38.93  ? 234 LEU A N   1 
ATOM   1600  C CA  . LEU A 1 234 ? 15.906  -9.263  -6.566  1.00 39.48  ? 234 LEU A CA  1 
ATOM   1601  C C   . LEU A 1 234 ? 16.170  -10.166 -5.358  1.00 36.53  ? 234 LEU A C   1 
ATOM   1602  O O   . LEU A 1 234 ? 15.220  -10.735 -4.812  1.00 32.06  ? 234 LEU A O   1 
ATOM   1603  C CB  . LEU A 1 234 ? 15.045  -10.014 -7.589  1.00 35.60  ? 234 LEU A CB  1 
ATOM   1604  C CG  . LEU A 1 234 ? 14.443  -9.261  -8.778  1.00 38.78  ? 234 LEU A CG  1 
ATOM   1605  C CD1 . LEU A 1 234 ? 13.762  -10.225 -9.749  1.00 37.45  ? 234 LEU A CD1 1 
ATOM   1606  C CD2 . LEU A 1 234 ? 13.459  -8.197  -8.329  1.00 38.64  ? 234 LEU A CD2 1 
ATOM   1607  N N   . THR A 1 235 ? 17.421  -10.302 -4.921  1.00 36.36  ? 235 THR A N   1 
ATOM   1608  C CA  . THR A 1 235 ? 17.787  -11.125 -3.773  1.00 38.19  ? 235 THR A CA  1 
ATOM   1609  C C   . THR A 1 235 ? 18.499  -10.286 -2.719  1.00 41.75  ? 235 THR A C   1 
ATOM   1610  O O   . THR A 1 235 ? 18.886  -9.135  -2.959  1.00 37.40  ? 235 THR A O   1 
ATOM   1611  C CB  . THR A 1 235 ? 18.691  -12.288 -4.181  1.00 34.01  ? 235 THR A CB  1 
ATOM   1612  O OG1 . THR A 1 235 ? 19.796  -11.780 -4.929  1.00 41.22  ? 235 THR A OG1 1 
ATOM   1613  C CG2 . THR A 1 235 ? 17.928  -13.306 -5.020  1.00 35.29  ? 235 THR A CG2 1 
ATOM   1614  N N   . ASP A 1 236 ? 18.666  -10.893 -1.542  1.00 37.85  ? 236 ASP A N   1 
ATOM   1615  C CA  . ASP A 1 236 ? 19.372  -10.290 -0.411  1.00 38.67  ? 236 ASP A CA  1 
ATOM   1616  C C   . ASP A 1 236 ? 19.727  -11.413 0.551   1.00 43.39  ? 236 ASP A C   1 
ATOM   1617  O O   . ASP A 1 236 ? 19.541  -12.593 0.231   1.00 44.50  ? 236 ASP A O   1 
ATOM   1618  C CB  . ASP A 1 236 ? 18.528  -9.209  0.272   1.00 38.33  ? 236 ASP A CB  1 
ATOM   1619  C CG  . ASP A 1 236 ? 17.119  -9.678  0.595   1.00 43.94  ? 236 ASP A CG  1 
ATOM   1620  O OD1 . ASP A 1 236 ? 16.939  -10.855 0.992   1.00 48.97  ? 236 ASP A OD1 1 
ATOM   1621  O OD2 . ASP A 1 236 ? 16.181  -8.868  0.464   1.00 46.26  ? 236 ASP A OD2 1 
ATOM   1622  N N   . THR A 1 237 ? 20.214  -11.054 1.746   1.00 39.32  ? 237 THR A N   1 
ATOM   1623  C CA  . THR A 1 237 ? 20.605  -12.085 2.709   1.00 35.35  ? 237 THR A CA  1 
ATOM   1624  C C   . THR A 1 237 ? 19.431  -12.993 3.038   1.00 38.31  ? 237 THR A C   1 
ATOM   1625  O O   . THR A 1 237 ? 19.580  -14.221 3.122   1.00 31.43  ? 237 THR A O   1 
ATOM   1626  C CB  . THR A 1 237 ? 21.151  -11.454 3.999   1.00 38.56  ? 237 THR A CB  1 
ATOM   1627  O OG1 . THR A 1 237 ? 22.162  -10.483 3.691   1.00 36.24  ? 237 THR A OG1 1 
ATOM   1628  C CG2 . THR A 1 237 ? 21.757  -12.527 4.903   1.00 33.05  ? 237 THR A CG2 1 
ATOM   1629  N N   . GLN A 1 238 ? 18.249  -12.406 3.203   1.00 36.83  ? 238 GLN A N   1 
ATOM   1630  C CA  . GLN A 1 238 ? 17.084  -13.145 3.660   1.00 44.08  ? 238 GLN A CA  1 
ATOM   1631  C C   . GLN A 1 238 ? 16.313  -13.797 2.525   1.00 44.33  ? 238 GLN A C   1 
ATOM   1632  O O   . GLN A 1 238 ? 15.519  -14.709 2.784   1.00 40.54  ? 238 GLN A O   1 
ATOM   1633  C CB  . GLN A 1 238 ? 16.147  -12.216 4.447   1.00 43.15  ? 238 GLN A CB  1 
ATOM   1634  C CG  . GLN A 1 238 ? 16.668  -11.826 5.826   1.00 42.65  ? 238 GLN A CG  1 
ATOM   1635  C CD  . GLN A 1 238 ? 15.550  -11.425 6.778   1.00 55.75  ? 238 GLN A CD  1 
ATOM   1636  O OE1 . GLN A 1 238 ? 15.597  -11.721 7.979   1.00 50.58  ? 238 GLN A OE1 1 
ATOM   1637  N NE2 . GLN A 1 238 ? 14.526  -10.756 6.240   1.00 55.17  ? 238 GLN A NE2 1 
ATOM   1638  N N   . ASN A 1 239 ? 16.543  -13.380 1.278   1.00 39.35  ? 239 ASN A N   1 
ATOM   1639  C CA  . ASN A 1 239 ? 15.719  -13.816 0.151   1.00 41.10  ? 239 ASN A CA  1 
ATOM   1640  C C   . ASN A 1 239 ? 16.615  -14.361 -0.951  1.00 36.23  ? 239 ASN A C   1 
ATOM   1641  O O   . ASN A 1 239 ? 17.153  -13.606 -1.766  1.00 38.71  ? 239 ASN A O   1 
ATOM   1642  C CB  . ASN A 1 239 ? 14.848  -12.674 -0.344  1.00 35.31  ? 239 ASN A CB  1 
ATOM   1643  C CG  . ASN A 1 239 ? 13.861  -12.245 0.691   1.00 38.85  ? 239 ASN A CG  1 
ATOM   1644  O OD1 . ASN A 1 239 ? 12.937  -12.983 1.013   1.00 45.04  ? 239 ASN A OD1 1 
ATOM   1645  N ND2 . ASN A 1 239 ? 14.065  -11.063 1.254   1.00 43.49  ? 239 ASN A ND2 1 
ATOM   1646  N N   . GLN A 1 240 ? 16.780  -15.674 -0.962  1.00 38.58  ? 240 GLN A N   1 
ATOM   1647  C CA  . GLN A 1 240 ? 17.626  -16.349 -1.934  1.00 39.29  ? 240 GLN A CA  1 
ATOM   1648  C C   . GLN A 1 240 ? 16.788  -17.137 -2.932  1.00 37.43  ? 240 GLN A C   1 
ATOM   1649  O O   . GLN A 1 240 ? 17.285  -18.081 -3.552  1.00 36.02  ? 240 GLN A O   1 
ATOM   1650  C CB  . GLN A 1 240 ? 18.640  -17.247 -1.213  1.00 40.62  ? 240 GLN A CB  1 
ATOM   1651  C CG  . GLN A 1 240 ? 19.952  -17.552 -1.983  1.00 47.35  ? 240 GLN A CG  1 
ATOM   1652  C CD  . GLN A 1 240 ? 20.885  -16.352 -2.155  1.00 43.68  ? 240 GLN A CD  1 
ATOM   1653  O OE1 . GLN A 1 240 ? 20.688  -15.280 -1.568  1.00 43.84  ? 240 GLN A OE1 1 
ATOM   1654  N NE2 . GLN A 1 240 ? 21.914  -16.535 -2.964  1.00 42.31  ? 240 GLN A NE2 1 
ATOM   1655  N N   . PHE A 1 241 ? 15.513  -16.777 -3.078  1.00 31.09  ? 241 PHE A N   1 
ATOM   1656  C CA  . PHE A 1 241 ? 14.650  -17.341 -4.098  1.00 30.12  ? 241 PHE A CA  1 
ATOM   1657  C C   . PHE A 1 241 ? 14.216  -16.225 -5.028  1.00 35.39  ? 241 PHE A C   1 
ATOM   1658  O O   . PHE A 1 241 ? 14.081  -15.066 -4.620  1.00 34.21  ? 241 PHE A O   1 
ATOM   1659  C CB  . PHE A 1 241 ? 13.386  -18.007 -3.529  1.00 30.87  ? 241 PHE A CB  1 
ATOM   1660  C CG  . PHE A 1 241 ? 13.605  -19.381 -2.966  1.00 33.00  ? 241 PHE A CG  1 
ATOM   1661  C CD1 . PHE A 1 241 ? 14.510  -20.248 -3.533  1.00 33.55  ? 241 PHE A CD1 1 
ATOM   1662  C CD2 . PHE A 1 241 ? 12.869  -19.812 -1.879  1.00 36.44  ? 241 PHE A CD2 1 
ATOM   1663  C CE1 . PHE A 1 241 ? 14.696  -21.517 -3.014  1.00 35.97  ? 241 PHE A CE1 1 
ATOM   1664  C CE2 . PHE A 1 241 ? 13.054  -21.080 -1.355  1.00 35.14  ? 241 PHE A CE2 1 
ATOM   1665  C CZ  . PHE A 1 241 ? 13.969  -21.930 -1.921  1.00 35.86  ? 241 PHE A CZ  1 
ATOM   1666  N N   . ILE A 1 242 ? 13.971  -16.590 -6.275  1.00 28.03  ? 242 ILE A N   1 
ATOM   1667  C CA  . ILE A 1 242 ? 13.352  -15.689 -7.225  1.00 31.56  ? 242 ILE A CA  1 
ATOM   1668  C C   . ILE A 1 242 ? 12.282  -16.474 -7.964  1.00 30.17  ? 242 ILE A C   1 
ATOM   1669  O O   . ILE A 1 242 ? 12.433  -17.675 -8.203  1.00 28.83  ? 242 ILE A O   1 
ATOM   1670  C CB  . ILE A 1 242 ? 14.419  -15.065 -8.158  1.00 38.15  ? 242 ILE A CB  1 
ATOM   1671  C CG1 . ILE A 1 242 ? 14.931  -13.767 -7.531  1.00 36.22  ? 242 ILE A CG1 1 
ATOM   1672  C CG2 . ILE A 1 242 ? 13.905  -14.796 -9.548  1.00 31.61  ? 242 ILE A CG2 1 
ATOM   1673  C CD1 . ILE A 1 242 ? 16.156  -13.220 -8.199  1.00 43.74  ? 242 ILE A CD1 1 
ATOM   1674  N N   . THR A 1 243 ? 11.164  -15.821 -8.250  1.00 28.59  ? 243 THR A N   1 
ATOM   1675  C CA  . THR A 1 243 ? 10.133  -16.406 -9.089  1.00 29.52  ? 243 THR A CA  1 
ATOM   1676  C C   . THR A 1 243 ? 10.328  -15.930 -10.528 1.00 30.68  ? 243 THR A C   1 
ATOM   1677  O O   . THR A 1 243 ? 10.691  -14.776 -10.757 1.00 30.21  ? 243 THR A O   1 
ATOM   1678  C CB  . THR A 1 243 ? 8.756   -16.040 -8.533  1.00 28.23  ? 243 THR A CB  1 
ATOM   1679  O OG1 . THR A 1 243 ? 8.123   -17.223 -8.053  1.00 37.42  ? 243 THR A OG1 1 
ATOM   1680  C CG2 . THR A 1 243 ? 7.873   -15.369 -9.532  1.00 30.91  ? 243 THR A CG2 1 
ATOM   1681  N N   . VAL A 1 244 ? 10.151  -16.843 -11.490 1.00 28.90  ? 244 VAL A N   1 
ATOM   1682  C CA  . VAL A 1 244 ? 10.348  -16.562 -12.916 1.00 28.02  ? 244 VAL A CA  1 
ATOM   1683  C C   . VAL A 1 244 ? 9.195   -17.196 -13.673 1.00 28.15  ? 244 VAL A C   1 
ATOM   1684  O O   . VAL A 1 244 ? 9.060   -18.424 -13.675 1.00 31.29  ? 244 VAL A O   1 
ATOM   1685  C CB  . VAL A 1 244 ? 11.684  -17.106 -13.465 1.00 28.27  ? 244 VAL A CB  1 
ATOM   1686  C CG1 . VAL A 1 244 ? 11.986  -16.504 -14.838 1.00 31.56  ? 244 VAL A CG1 1 
ATOM   1687  C CG2 . VAL A 1 244 ? 12.831  -16.847 -12.504 1.00 28.52  ? 244 VAL A CG2 1 
ATOM   1688  N N   . GLU A 1 245 ? 8.373   -16.378 -14.329 1.00 26.45  ? 245 GLU A N   1 
ATOM   1689  C CA  . GLU A 1 245 ? 7.131   -16.888 -14.874 1.00 25.81  ? 245 GLU A CA  1 
ATOM   1690  C C   . GLU A 1 245 ? 6.847   -16.333 -16.262 1.00 27.98  ? 245 GLU A C   1 
ATOM   1691  O O   . GLU A 1 245 ? 7.157   -15.183 -16.565 1.00 28.13  ? 245 GLU A O   1 
ATOM   1692  C CB  . GLU A 1 245 ? 5.947   -16.541 -13.982 1.00 28.76  ? 245 GLU A CB  1 
ATOM   1693  C CG  . GLU A 1 245 ? 6.219   -16.526 -12.476 1.00 35.91  ? 245 GLU A CG  1 
ATOM   1694  C CD  . GLU A 1 245 ? 4.936   -16.271 -11.688 1.00 37.08  ? 245 GLU A CD  1 
ATOM   1695  O OE1 . GLU A 1 245 ? 4.372   -15.165 -11.846 1.00 37.32  ? 245 GLU A OE1 1 
ATOM   1696  O OE2 . GLU A 1 245 ? 4.483   -17.176 -10.944 1.00 31.21  ? 245 GLU A OE2 1 
ATOM   1697  N N   . THR A 1 246 ? 6.202   -17.162 -17.082 1.00 26.93  ? 246 THR A N   1 
ATOM   1698  C CA  . THR A 1 246 ? 5.556   -16.683 -18.292 1.00 31.22  ? 246 THR A CA  1 
ATOM   1699  C C   . THR A 1 246 ? 4.530   -15.616 -17.938 1.00 32.95  ? 246 THR A C   1 
ATOM   1700  O O   . THR A 1 246 ? 3.678   -15.827 -17.066 1.00 35.26  ? 246 THR A O   1 
ATOM   1701  C CB  . THR A 1 246 ? 4.875   -17.842 -19.023 1.00 22.93  ? 246 THR A CB  1 
ATOM   1702  O OG1 . THR A 1 246 ? 5.874   -18.644 -19.665 1.00 35.82  ? 246 THR A OG1 1 
ATOM   1703  C CG2 . THR A 1 246 ? 3.892   -17.310 -20.066 1.00 25.30  ? 246 THR A CG2 1 
ATOM   1704  N N   . TYR A 1 247 ? 4.606   -14.480 -18.628 1.00 31.94  ? 247 TYR A N   1 
ATOM   1705  C CA  . TYR A 1 247 ? 3.735   -13.335 -18.405 1.00 29.65  ? 247 TYR A CA  1 
ATOM   1706  C C   . TYR A 1 247 ? 2.744   -13.182 -19.554 1.00 37.50  ? 247 TYR A C   1 
ATOM   1707  O O   . TYR A 1 247 ? 3.150   -13.130 -20.724 1.00 31.54  ? 247 TYR A O   1 
ATOM   1708  C CB  . TYR A 1 247 ? 4.570   -12.068 -18.269 1.00 31.90  ? 247 TYR A CB  1 
ATOM   1709  C CG  . TYR A 1 247 ? 3.767   -10.832 -17.974 1.00 37.01  ? 247 TYR A CG  1 
ATOM   1710  C CD1 . TYR A 1 247 ? 3.120   -10.141 -18.992 1.00 38.10  ? 247 TYR A CD1 1 
ATOM   1711  C CD2 . TYR A 1 247 ? 3.676   -10.337 -16.674 1.00 30.93  ? 247 TYR A CD2 1 
ATOM   1712  C CE1 . TYR A 1 247 ? 2.391   -8.994  -18.728 1.00 43.09  ? 247 TYR A CE1 1 
ATOM   1713  C CE2 . TYR A 1 247 ? 2.951   -9.200  -16.401 1.00 34.80  ? 247 TYR A CE2 1 
ATOM   1714  C CZ  . TYR A 1 247 ? 2.310   -8.532  -17.433 1.00 38.22  ? 247 TYR A CZ  1 
ATOM   1715  O OH  . TYR A 1 247 ? 1.590   -7.401  -17.171 1.00 43.92  ? 247 TYR A OH  1 
ATOM   1716  N N   . HIS A 1 248 ? 1.458   -13.063 -19.213 1.00 32.95  ? 248 HIS A N   1 
ATOM   1717  C CA  . HIS A 1 248 ? 0.363   -12.946 -20.170 1.00 35.04  ? 248 HIS A CA  1 
ATOM   1718  C C   . HIS A 1 248 ? -0.221  -11.535 -20.161 1.00 38.06  ? 248 HIS A C   1 
ATOM   1719  O O   . HIS A 1 248 ? -0.316  -10.901 -19.106 1.00 36.11  ? 248 HIS A O   1 
ATOM   1720  C CB  . HIS A 1 248 ? -0.760  -13.935 -19.837 1.00 35.94  ? 248 HIS A CB  1 
ATOM   1721  C CG  . HIS A 1 248 ? -0.340  -15.370 -19.847 1.00 32.73  ? 248 HIS A CG  1 
ATOM   1722  N ND1 . HIS A 1 248 ? -0.715  -16.247 -20.840 1.00 32.38  ? 248 HIS A ND1 1 
ATOM   1723  C CD2 . HIS A 1 248 ? 0.406   -16.086 -18.975 1.00 34.69  ? 248 HIS A CD2 1 
ATOM   1724  C CE1 . HIS A 1 248 ? -0.215  -17.442 -20.582 1.00 37.03  ? 248 HIS A CE1 1 
ATOM   1725  N NE2 . HIS A 1 248 ? 0.472   -17.369 -19.455 1.00 34.83  ? 248 HIS A NE2 1 
ATOM   1726  N N   . ARG A 1 249 ? -0.637  -11.051 -21.332 1.00 42.68  ? 249 ARG A N   1 
ATOM   1727  C CA  . ARG A 1 249 ? -1.437  -9.833  -21.400 1.00 39.20  ? 249 ARG A CA  1 
ATOM   1728  C C   . ARG A 1 249 ? -2.873  -10.186 -21.053 1.00 39.14  ? 249 ARG A C   1 
ATOM   1729  O O   . ARG A 1 249 ? -3.469  -11.066 -21.684 1.00 42.12  ? 249 ARG A O   1 
ATOM   1730  C CB  . ARG A 1 249 ? -1.390  -9.205  -22.793 1.00 45.05  ? 249 ARG A CB  1 
ATOM   1731  C CG  . ARG A 1 249 ? -0.021  -8.911  -23.335 1.00 48.20  ? 249 ARG A CG  1 
ATOM   1732  C CD  . ARG A 1 249 ? -0.085  -8.599  -24.835 1.00 57.61  ? 249 ARG A CD  1 
ATOM   1733  N NE  . ARG A 1 249 ? -0.418  -9.787  -25.617 1.00 63.21  ? 249 ARG A NE  1 
ATOM   1734  C CZ  . ARG A 1 249 ? 0.280   -10.233 -26.654 1.00 63.65  ? 249 ARG A CZ  1 
ATOM   1735  N NH1 . ARG A 1 249 ? 1.344   -9.585  -27.103 1.00 67.67  ? 249 ARG A NH1 1 
ATOM   1736  N NH2 . ARG A 1 249 ? -0.096  -11.362 -27.252 1.00 65.38  ? 249 ARG A NH2 1 
ATOM   1737  N N   . ALA A 1 250 ? -3.435  -9.501  -20.063 1.00 35.54  ? 250 ALA A N   1 
ATOM   1738  C CA  . ALA A 1 250 ? -4.729  -9.875  -19.510 1.00 43.69  ? 250 ALA A CA  1 
ATOM   1739  C C   . ALA A 1 250 ? -5.832  -8.973  -20.044 1.00 45.52  ? 250 ALA A C   1 
ATOM   1740  O O   . ALA A 1 250 ? -5.692  -7.747  -20.052 1.00 43.00  ? 250 ALA A O   1 
ATOM   1741  C CB  . ALA A 1 250 ? -4.712  -9.810  -17.982 1.00 40.07  ? 250 ALA A CB  1 
ATOM   1742  N N   . ASP A 1 251 ? -6.929  -9.591  -20.488 1.00 51.04  ? 251 ASP A N   1 
ATOM   1743  C CA  . ASP A 1 251 ? -8.180  -8.859  -20.644 1.00 50.42  ? 251 ASP A CA  1 
ATOM   1744  C C   . ASP A 1 251 ? -8.678  -8.364  -19.290 1.00 47.83  ? 251 ASP A C   1 
ATOM   1745  O O   . ASP A 1 251 ? -8.799  -7.156  -19.049 1.00 50.58  ? 251 ASP A O   1 
ATOM   1746  C CB  . ASP A 1 251 ? -9.225  -9.756  -21.315 1.00 50.70  ? 251 ASP A CB  1 
ATOM   1747  C CG  . ASP A 1 251 ? -10.338 -8.958  -21.992 1.00 62.36  ? 251 ASP A CG  1 
ATOM   1748  O OD1 . ASP A 1 251 ? -10.807 -9.394  -23.072 1.00 64.46  ? 251 ASP A OD1 1 
ATOM   1749  O OD2 . ASP A 1 251 ? -10.745 -7.904  -21.440 1.00 62.45  ? 251 ASP A OD2 1 
ATOM   1750  N N   . GLN A 1 252 ? -8.958  -9.291  -18.388 1.00 42.16  ? 252 GLN A N   1 
ATOM   1751  C CA  . GLN A 1 252 ? -9.413  -8.965  -17.050 1.00 42.82  ? 252 GLN A CA  1 
ATOM   1752  C C   . GLN A 1 252 ? -8.297  -9.236  -16.056 1.00 38.75  ? 252 GLN A C   1 
ATOM   1753  O O   . GLN A 1 252 ? -7.683  -10.309 -16.081 1.00 37.45  ? 252 GLN A O   1 
ATOM   1754  C CB  . GLN A 1 252 ? -10.659 -9.778  -16.695 1.00 45.47  ? 252 GLN A CB  1 
ATOM   1755  C CG  . GLN A 1 252 ? -11.841 -9.483  -17.606 1.00 49.02  ? 252 GLN A CG  1 
ATOM   1756  C CD  . GLN A 1 252 ? -12.278 -8.023  -17.545 1.00 51.77  ? 252 GLN A CD  1 
ATOM   1757  O OE1 . GLN A 1 252 ? -12.041 -7.325  -16.550 1.00 49.33  ? 252 GLN A OE1 1 
ATOM   1758  N NE2 . GLN A 1 252 ? -12.919 -7.554  -18.616 1.00 58.46  ? 252 GLN A NE2 1 
ATOM   1759  N N   . ARG A 1 253 ? -7.998  -8.241  -15.236 1.00 32.25  ? 253 ARG A N   1 
ATOM   1760  C CA  . ARG A 1 253 ? -7.314  -8.431  -13.971 1.00 31.93  ? 253 ARG A CA  1 
ATOM   1761  C C   . ARG A 1 253 ? -8.357  -8.364  -12.868 1.00 36.78  ? 253 ARG A C   1 
ATOM   1762  O O   . ARG A 1 253 ? -9.441  -7.795  -13.048 1.00 38.82  ? 253 ARG A O   1 
ATOM   1763  C CB  . ARG A 1 253 ? -6.227  -7.380  -13.754 1.00 35.81  ? 253 ARG A CB  1 
ATOM   1764  C CG  . ARG A 1 253 ? -5.524  -6.972  -15.034 1.00 41.68  ? 253 ARG A CG  1 
ATOM   1765  C CD  . ARG A 1 253 ? -4.346  -6.034  -14.802 1.00 44.10  ? 253 ARG A CD  1 
ATOM   1766  N NE  . ARG A 1 253 ? -3.215  -6.696  -14.163 1.00 52.61  ? 253 ARG A NE  1 
ATOM   1767  C CZ  . ARG A 1 253 ? -2.314  -7.438  -14.799 1.00 54.51  ? 253 ARG A CZ  1 
ATOM   1768  N NH1 . ARG A 1 253 ? -2.381  -7.639  -16.105 1.00 48.86  ? 253 ARG A NH1 1 
ATOM   1769  N NH2 . ARG A 1 253 ? -1.322  -7.995  -14.105 1.00 48.49  ? 253 ARG A NH2 1 
ATOM   1770  N N   . PHE A 1 254 ? -8.045  -8.996  -11.739 1.00 31.56  ? 254 PHE A N   1 
ATOM   1771  C CA  . PHE A 1 254 ? -8.976  -9.039  -10.619 1.00 26.13  ? 254 PHE A CA  1 
ATOM   1772  C C   . PHE A 1 254 ? -8.205  -9.467  -9.380  1.00 26.34  ? 254 PHE A C   1 
ATOM   1773  O O   . PHE A 1 254 ? -7.127  -10.063 -9.470  1.00 24.71  ? 254 PHE A O   1 
ATOM   1774  C CB  . PHE A 1 254 ? -10.157 -9.989  -10.892 1.00 24.59  ? 254 PHE A CB  1 
ATOM   1775  C CG  . PHE A 1 254 ? -9.785  -11.448 -10.869 1.00 28.78  ? 254 PHE A CG  1 
ATOM   1776  C CD1 . PHE A 1 254 ? -9.840  -12.173 -9.693  1.00 24.62  ? 254 PHE A CD1 1 
ATOM   1777  C CD2 . PHE A 1 254 ? -9.380  -12.092 -12.031 1.00 28.71  ? 254 PHE A CD2 1 
ATOM   1778  C CE1 . PHE A 1 254 ? -9.478  -13.514 -9.667  1.00 30.09  ? 254 PHE A CE1 1 
ATOM   1779  C CE2 . PHE A 1 254 ? -9.018  -13.430 -12.018 1.00 28.46  ? 254 PHE A CE2 1 
ATOM   1780  C CZ  . PHE A 1 254 ? -9.063  -14.147 -10.834 1.00 28.03  ? 254 PHE A CZ  1 
ATOM   1781  N N   . PHE A 1 255 ? -8.755  -9.134  -8.219  1.00 20.99  ? 255 PHE A N   1 
ATOM   1782  C CA  . PHE A 1 255 ? -8.362  -9.842  -7.016  1.00 23.51  ? 255 PHE A CA  1 
ATOM   1783  C C   . PHE A 1 255 ? -9.594  -10.039 -6.142  1.00 21.70  ? 255 PHE A C   1 
ATOM   1784  O O   . PHE A 1 255 ? -10.547 -9.254  -6.188  1.00 25.44  ? 255 PHE A O   1 
ATOM   1785  C CB  . PHE A 1 255 ? -7.180  -9.145  -6.295  1.00 17.37  ? 255 PHE A CB  1 
ATOM   1786  C CG  . PHE A 1 255 ? -7.539  -7.905  -5.524  1.00 24.14  ? 255 PHE A CG  1 
ATOM   1787  C CD1 . PHE A 1 255 ? -7.847  -7.976  -4.175  1.00 25.55  ? 255 PHE A CD1 1 
ATOM   1788  C CD2 . PHE A 1 255 ? -7.509  -6.662  -6.126  1.00 24.85  ? 255 PHE A CD2 1 
ATOM   1789  C CE1 . PHE A 1 255 ? -8.159  -6.822  -3.447  1.00 22.99  ? 255 PHE A CE1 1 
ATOM   1790  C CE2 . PHE A 1 255 ? -7.805  -5.512  -5.404  1.00 24.50  ? 255 PHE A CE2 1 
ATOM   1791  C CZ  . PHE A 1 255 ? -8.141  -5.600  -4.066  1.00 21.92  ? 255 PHE A CZ  1 
ATOM   1792  N N   . PHE A 1 256 ? -9.591  -11.148 -5.410  1.00 22.96  ? 256 PHE A N   1 
ATOM   1793  C CA  . PHE A 1 256 ? -10.629 -11.506 -4.452  1.00 22.18  ? 256 PHE A CA  1 
ATOM   1794  C C   . PHE A 1 256 ? -10.066 -11.376 -3.038  1.00 26.83  ? 256 PHE A C   1 
ATOM   1795  O O   . PHE A 1 256 ? -8.901  -11.712 -2.795  1.00 26.69  ? 256 PHE A O   1 
ATOM   1796  C CB  . PHE A 1 256 ? -11.111 -12.940 -4.658  1.00 22.65  ? 256 PHE A CB  1 
ATOM   1797  C CG  . PHE A 1 256 ? -11.715 -13.217 -6.006  1.00 26.12  ? 256 PHE A CG  1 
ATOM   1798  C CD1 . PHE A 1 256 ? -12.195 -12.200 -6.808  1.00 23.82  ? 256 PHE A CD1 1 
ATOM   1799  C CD2 . PHE A 1 256 ? -11.846 -14.526 -6.451  1.00 24.89  ? 256 PHE A CD2 1 
ATOM   1800  C CE1 . PHE A 1 256 ? -12.759 -12.478 -8.034  1.00 21.35  ? 256 PHE A CE1 1 
ATOM   1801  C CE2 . PHE A 1 256 ? -12.400 -14.798 -7.696  1.00 26.17  ? 256 PHE A CE2 1 
ATOM   1802  C CZ  . PHE A 1 256 ? -12.859 -13.783 -8.471  1.00 21.23  ? 256 PHE A CZ  1 
ATOM   1803  N N   . GLU A 1 257 ? -10.885 -10.897 -2.096  1.00 21.88  ? 257 GLU A N   1 
ATOM   1804  C CA  . GLU A 1 257 ? -10.421 -10.698 -0.725  1.00 21.51  ? 257 GLU A CA  1 
ATOM   1805  C C   . GLU A 1 257 ? -11.362 -11.412 0.231   1.00 22.95  ? 257 GLU A C   1 
ATOM   1806  O O   . GLU A 1 257 ? -12.591 -11.365 0.055   1.00 18.57  ? 257 GLU A O   1 
ATOM   1807  C CB  . GLU A 1 257 ? -10.320 -9.205  -0.376  1.00 18.65  ? 257 GLU A CB  1 
ATOM   1808  C CG  . GLU A 1 257 ? -9.734  -8.919  0.978   1.00 17.46  ? 257 GLU A CG  1 
ATOM   1809  C CD  . GLU A 1 257 ? -9.176  -7.503  1.126   1.00 20.30  ? 257 GLU A CD  1 
ATOM   1810  O OE1 . GLU A 1 257 ? -9.662  -6.583  0.436   1.00 24.48  ? 257 GLU A OE1 1 
ATOM   1811  O OE2 . GLU A 1 257 ? -8.248  -7.300  1.938   1.00 18.73  ? 257 GLU A OE2 1 
ATOM   1812  N N   . TYR A 1 258 ? -10.766 -12.087 1.231   1.00 19.79  ? 258 TYR A N   1 
ATOM   1813  C CA  . TYR A 1 258 ? -11.461 -12.945 2.181   1.00 18.82  ? 258 TYR A CA  1 
ATOM   1814  C C   . TYR A 1 258 ? -11.062 -12.606 3.612   1.00 20.69  ? 258 TYR A C   1 
ATOM   1815  O O   . TYR A 1 258 ? -9.969  -12.096 3.883   1.00 20.22  ? 258 TYR A O   1 
ATOM   1816  C CB  . TYR A 1 258 ? -11.168 -14.459 1.964   1.00 19.76  ? 258 TYR A CB  1 
ATOM   1817  C CG  . TYR A 1 258 ? -11.387 -14.958 0.552   1.00 22.09  ? 258 TYR A CG  1 
ATOM   1818  C CD1 . TYR A 1 258 ? -10.473 -14.662 -0.456  1.00 17.47  ? 258 TYR A CD1 1 
ATOM   1819  C CD2 . TYR A 1 258 ? -12.486 -15.735 0.232   1.00 20.69  ? 258 TYR A CD2 1 
ATOM   1820  C CE1 . TYR A 1 258 ? -10.662 -15.091 -1.746  1.00 22.84  ? 258 TYR A CE1 1 
ATOM   1821  C CE2 . TYR A 1 258 ? -12.691 -16.179 -1.067  1.00 23.76  ? 258 TYR A CE2 1 
ATOM   1822  C CZ  . TYR A 1 258 ? -11.759 -15.863 -2.045  1.00 26.36  ? 258 TYR A CZ  1 
ATOM   1823  O OH  . TYR A 1 258 ? -11.922 -16.311 -3.324  1.00 24.05  ? 258 TYR A OH  1 
ATOM   1824  N N   . HIS A 1 259 ? -11.963 -12.934 4.525   1.00 22.11  ? 259 HIS A N   1 
ATOM   1825  C CA  . HIS A 1 259 ? -11.722 -12.920 5.958   1.00 24.31  ? 259 HIS A CA  1 
ATOM   1826  C C   . HIS A 1 259 ? -11.845 -14.347 6.454   1.00 23.16  ? 259 HIS A C   1 
ATOM   1827  O O   . HIS A 1 259 ? -12.836 -15.019 6.166   1.00 21.70  ? 259 HIS A O   1 
ATOM   1828  C CB  . HIS A 1 259 ? -12.730 -12.025 6.693   1.00 23.22  ? 259 HIS A CB  1 
ATOM   1829  C CG  . HIS A 1 259 ? -12.584 -12.057 8.183   1.00 22.26  ? 259 HIS A CG  1 
ATOM   1830  N ND1 . HIS A 1 259 ? -13.250 -12.965 8.980   1.00 23.82  ? 259 HIS A ND1 1 
ATOM   1831  C CD2 . HIS A 1 259 ? -11.813 -11.323 9.016   1.00 20.73  ? 259 HIS A CD2 1 
ATOM   1832  C CE1 . HIS A 1 259 ? -12.912 -12.775 10.244  1.00 26.56  ? 259 HIS A CE1 1 
ATOM   1833  N NE2 . HIS A 1 259 ? -12.034 -11.789 10.292  1.00 24.84  ? 259 HIS A NE2 1 
ATOM   1834  N N   . LEU A 1 260 ? -10.848 -14.799 7.201   1.00 23.23  ? 260 LEU A N   1 
ATOM   1835  C CA  . LEU A 1 260 ? -10.747 -16.177 7.654   1.00 17.26  ? 260 LEU A CA  1 
ATOM   1836  C C   . LEU A 1 260 ? -10.761 -16.217 9.172   1.00 19.65  ? 260 LEU A C   1 
ATOM   1837  O O   . LEU A 1 260 ? -10.007 -15.484 9.811   1.00 16.54  ? 260 LEU A O   1 
ATOM   1838  C CB  . LEU A 1 260 ? -9.462  -16.822 7.145   1.00 16.36  ? 260 LEU A CB  1 
ATOM   1839  C CG  . LEU A 1 260 ? -9.564  -17.462 5.771   1.00 26.90  ? 260 LEU A CG  1 
ATOM   1840  C CD1 . LEU A 1 260 ? -9.972  -16.413 4.703   1.00 21.58  ? 260 LEU A CD1 1 
ATOM   1841  C CD2 . LEU A 1 260 ? -8.231  -18.092 5.444   1.00 18.32  ? 260 LEU A CD2 1 
ATOM   1842  N N   . ASP A 1 261 ? -11.603 -17.083 9.734   1.00 18.90  ? 261 ASP A N   1 
ATOM   1843  C CA  . ASP A 1 261 ? -11.632 -17.358 11.162  1.00 20.13  ? 261 ASP A CA  1 
ATOM   1844  C C   . ASP A 1 261 ? -11.808 -18.868 11.341  1.00 22.51  ? 261 ASP A C   1 
ATOM   1845  O O   . ASP A 1 261 ? -11.788 -19.642 10.376  1.00 23.49  ? 261 ASP A O   1 
ATOM   1846  C CB  . ASP A 1 261 ? -12.719 -16.520 11.869  1.00 21.65  ? 261 ASP A CB  1 
ATOM   1847  C CG  . ASP A 1 261 ? -14.139 -16.800 11.366  1.00 23.23  ? 261 ASP A CG  1 
ATOM   1848  O OD1 . ASP A 1 261 ? -14.373 -17.806 10.649  1.00 24.39  ? 261 ASP A OD1 1 
ATOM   1849  O OD2 . ASP A 1 261 ? -15.041 -15.999 11.720  1.00 22.65  ? 261 ASP A OD2 1 
ATOM   1850  N N   . GLY A 1 262 ? -11.991 -19.298 12.579  1.00 24.55  ? 262 GLY A N   1 
ATOM   1851  C CA  . GLY A 1 262 ? -12.180 -20.714 12.823  1.00 25.83  ? 262 GLY A CA  1 
ATOM   1852  C C   . GLY A 1 262 ? -13.466 -21.303 12.275  1.00 23.81  ? 262 GLY A C   1 
ATOM   1853  O O   . GLY A 1 262 ? -13.669 -22.516 12.390  1.00 31.63  ? 262 GLY A O   1 
ATOM   1854  N N   . ASP A 1 263 ? -14.325 -20.493 11.659  1.00 28.35  ? 263 ASP A N   1 
ATOM   1855  C CA  . ASP A 1 263 ? -15.635 -20.915 11.169  1.00 26.64  ? 263 ASP A CA  1 
ATOM   1856  C C   . ASP A 1 263 ? -15.683 -21.078 9.652   1.00 25.32  ? 263 ASP A C   1 
ATOM   1857  O O   . ASP A 1 263 ? -16.263 -22.039 9.135   1.00 28.06  ? 263 ASP A O   1 
ATOM   1858  C CB  . ASP A 1 263 ? -16.695 -19.881 11.562  1.00 29.99  ? 263 ASP A CB  1 
ATOM   1859  C CG  . ASP A 1 263 ? -17.171 -20.035 12.987  1.00 28.37  ? 263 ASP A CG  1 
ATOM   1860  O OD1 . ASP A 1 263 ? -17.002 -21.117 13.580  1.00 32.72  ? 263 ASP A OD1 1 
ATOM   1861  O OD2 . ASP A 1 263 ? -17.727 -19.054 13.517  1.00 36.23  ? 263 ASP A OD2 1 
ATOM   1862  N N   . ARG A 1 264 ? -15.134 -20.122 8.913   1.00 26.87  ? 264 ARG A N   1 
ATOM   1863  C CA  . ARG A 1 264 ? -15.264 -20.056 7.444   1.00 24.39  ? 264 ARG A CA  1 
ATOM   1864  C C   . ARG A 1 264 ? -14.249 -19.123 6.858   1.00 22.40  ? 264 ARG A C   1 
ATOM   1865  O O   . ARG A 1 264 ? -13.688 -18.279 7.546   1.00 22.20  ? 264 ARG A O   1 
ATOM   1866  C CB  . ARG A 1 264 ? -16.638 -19.545 6.928   1.00 23.90  ? 264 ARG A CB  1 
ATOM   1867  C CG  . ARG A 1 264 ? -16.926 -18.167 7.568   1.00 26.33  ? 264 ARG A CG  1 
ATOM   1868  C CD  . ARG A 1 264 ? -16.445 -16.918 7.001   1.00 41.01  ? 264 ARG A CD  1 
ATOM   1869  N NE  . ARG A 1 264 ? -16.821 -15.746 7.877   1.00 41.70  ? 264 ARG A NE  1 
ATOM   1870  C CZ  . ARG A 1 264 ? -15.903 -14.886 8.273   1.00 34.88  ? 264 ARG A CZ  1 
ATOM   1871  N NH1 . ARG A 1 264 ? -14.580 -15.165 8.136   1.00 29.92  ? 264 ARG A NH1 1 
ATOM   1872  N NH2 . ARG A 1 264 ? -16.312 -13.768 8.795   1.00 33.79  ? 264 ARG A NH2 1 
ATOM   1873  N N   . ALA A 1 265 ? -14.147 -19.200 5.548   1.00 27.10  ? 265 ALA A N   1 
ATOM   1874  C CA  . ALA A 1 265 ? -13.622 -18.120 4.727   1.00 28.46  ? 265 ALA A CA  1 
ATOM   1875  C C   . ALA A 1 265 ? -14.760 -17.481 3.959   1.00 24.16  ? 265 ALA A C   1 
ATOM   1876  O O   . ALA A 1 265 ? -15.425 -18.148 3.152   1.00 25.33  ? 265 ALA A O   1 
ATOM   1877  C CB  . ALA A 1 265 ? -12.593 -18.671 3.743   1.00 20.01  ? 265 ALA A CB  1 
ATOM   1878  N N   . ARG A 1 266 ? -14.909 -16.191 4.109   1.00 26.73  ? 266 ARG A N   1 
ATOM   1879  C CA  . ARG A 1 266 ? -16.070 -15.504 3.550   1.00 30.87  ? 266 ARG A CA  1 
ATOM   1880  C C   . ARG A 1 266 ? -15.456 -14.639 2.461   1.00 22.76  ? 266 ARG A C   1 
ATOM   1881  O O   . ARG A 1 266 ? -14.464 -13.911 2.691   1.00 23.81  ? 266 ARG A O   1 
ATOM   1882  C CB  . ARG A 1 266 ? -16.794 -14.615 4.562   1.00 35.98  ? 266 ARG A CB  1 
ATOM   1883  C CG  . ARG A 1 266 ? -17.894 -13.738 4.052   1.00 29.09  ? 266 ARG A CG  1 
ATOM   1884  C CD  . ARG A 1 266 ? -18.998 -14.708 3.546   1.00 42.77  ? 266 ARG A CD  1 
ATOM   1885  N NE  . ARG A 1 266 ? -19.379 -15.318 4.826   1.00 39.23  ? 266 ARG A NE  1 
ATOM   1886  C CZ  . ARG A 1 266 ? -20.143 -16.362 5.167   1.00 40.08  ? 266 ARG A CZ  1 
ATOM   1887  N NH1 . ARG A 1 266 ? -20.943 -16.987 4.326   1.00 47.02  ? 266 ARG A NH1 1 
ATOM   1888  N NH2 . ARG A 1 266 ? -20.025 -16.852 6.393   1.00 36.02  ? 266 ARG A NH2 1 
ATOM   1889  N N   . PHE A 1 267 ? -15.890 -14.869 1.241   1.00 22.27  ? 267 PHE A N   1 
ATOM   1890  C CA  . PHE A 1 267 ? -15.640 -13.916 0.165   1.00 24.16  ? 267 PHE A CA  1 
ATOM   1891  C C   . PHE A 1 267 ? -16.100 -12.528 0.643   1.00 20.62  ? 267 PHE A C   1 
ATOM   1892  O O   . PHE A 1 267 ? -17.229 -12.401 1.117   1.00 19.93  ? 267 PHE A O   1 
ATOM   1893  C CB  . PHE A 1 267 ? -16.411 -14.390 -1.079  1.00 19.61  ? 267 PHE A CB  1 
ATOM   1894  C CG  . PHE A 1 267 ? -16.246 -13.489 -2.229  1.00 21.27  ? 267 PHE A CG  1 
ATOM   1895  C CD1 . PHE A 1 267 ? -17.145 -12.477 -2.466  1.00 21.35  ? 267 PHE A CD1 1 
ATOM   1896  C CD2 . PHE A 1 267 ? -15.134 -13.641 -3.032  1.00 24.00  ? 267 PHE A CD2 1 
ATOM   1897  C CE1 . PHE A 1 267 ? -16.962 -11.678 -3.513  1.00 30.23  ? 267 PHE A CE1 1 
ATOM   1898  C CE2 . PHE A 1 267 ? -14.936 -12.827 -4.046  1.00 31.96  ? 267 PHE A CE2 1 
ATOM   1899  C CZ  . PHE A 1 267 ? -15.839 -11.843 -4.292  1.00 27.29  ? 267 PHE A CZ  1 
ATOM   1900  N N   . LEU A 1 268 ? -15.254 -11.487 0.540   1.00 16.94  ? 268 LEU A N   1 
ATOM   1901  C CA  . LEU A 1 268 ? -15.676 -10.127 0.914   1.00 19.97  ? 268 LEU A CA  1 
ATOM   1902  C C   . LEU A 1 268 ? -16.023 -9.269  -0.295  1.00 23.45  ? 268 LEU A C   1 
ATOM   1903  O O   . LEU A 1 268 ? -17.090 -8.626  -0.333  1.00 21.28  ? 268 LEU A O   1 
ATOM   1904  C CB  . LEU A 1 268 ? -14.597 -9.390  1.753   1.00 23.95  ? 268 LEU A CB  1 
ATOM   1905  C CG  . LEU A 1 268 ? -14.144 -10.025 3.079   1.00 19.76  ? 268 LEU A CG  1 
ATOM   1906  C CD1 . LEU A 1 268 ? -13.017 -9.213  3.696   1.00 14.80  ? 268 LEU A CD1 1 
ATOM   1907  C CD2 . LEU A 1 268 ? -15.318 -10.212 4.108   1.00 19.74  ? 268 LEU A CD2 1 
ATOM   1908  N N   . HIS A 1 269 ? -15.151 -9.250  -1.300  1.00 17.77  ? 269 HIS A N   1 
ATOM   1909  C CA  . HIS A 1 269 ? -15.379 -8.446  -2.488  1.00 20.67  ? 269 HIS A CA  1 
ATOM   1910  C C   . HIS A 1 269 ? -14.357 -8.835  -3.533  1.00 26.25  ? 269 HIS A C   1 
ATOM   1911  O O   . HIS A 1 269 ? -13.251 -9.272  -3.203  1.00 23.88  ? 269 HIS A O   1 
ATOM   1912  C CB  . HIS A 1 269 ? -15.244 -6.954  -2.187  1.00 17.60  ? 269 HIS A CB  1 
ATOM   1913  C CG  . HIS A 1 269 ? -13.826 -6.526  -1.966  1.00 21.81  ? 269 HIS A CG  1 
ATOM   1914  N ND1 . HIS A 1 269 ? -13.034 -6.020  -2.976  1.00 25.37  ? 269 HIS A ND1 1 
ATOM   1915  C CD2 . HIS A 1 269 ? -13.050 -6.554  -0.857  1.00 19.16  ? 269 HIS A CD2 1 
ATOM   1916  C CE1 . HIS A 1 269 ? -11.838 -5.732  -2.493  1.00 24.24  ? 269 HIS A CE1 1 
ATOM   1917  N NE2 . HIS A 1 269 ? -11.820 -6.048  -1.209  1.00 23.56  ? 269 HIS A NE2 1 
ATOM   1918  N N   . SER A 1 270 ? -14.730 -8.651  -4.790  1.00 20.13  ? 270 SER A N   1 
ATOM   1919  C CA  . SER A 1 270 ? -13.786 -8.694  -5.890  1.00 26.21  ? 270 SER A CA  1 
ATOM   1920  C C   . SER A 1 270 ? -13.492 -7.256  -6.276  1.00 24.97  ? 270 SER A C   1 
ATOM   1921  O O   . SER A 1 270 ? -14.383 -6.409  -6.198  1.00 24.80  ? 270 SER A O   1 
ATOM   1922  C CB  . SER A 1 270 ? -14.357 -9.459  -7.089  1.00 21.44  ? 270 SER A CB  1 
ATOM   1923  O OG  . SER A 1 270 ? -15.323 -8.663  -7.788  1.00 31.23  ? 270 SER A OG  1 
ATOM   1924  N N   . SER A 1 271 ? -12.250 -6.985  -6.690  1.00 22.57  ? 271 SER A N   1 
ATOM   1925  C CA  . SER A 1 271 ? -11.884 -5.669  -7.198  1.00 24.89  ? 271 SER A CA  1 
ATOM   1926  C C   . SER A 1 271 ? -10.926 -5.813  -8.372  1.00 22.70  ? 271 SER A C   1 
ATOM   1927  O O   . SER A 1 271 ? -10.451 -6.907  -8.687  1.00 29.71  ? 271 SER A O   1 
ATOM   1928  C CB  . SER A 1 271 ? -11.275 -4.785  -6.099  1.00 22.90  ? 271 SER A CB  1 
ATOM   1929  O OG  . SER A 1 271 ? -12.287 -4.402  -5.183  1.00 25.39  ? 271 SER A OG  1 
ATOM   1930  N N   . ILE A 1 272 ? -10.629 -4.677  -9.006  1.00 26.37  ? 272 ILE A N   1 
ATOM   1931  C CA  . ILE A 1 272 ? -9.787  -4.587  -10.197 1.00 27.25  ? 272 ILE A CA  1 
ATOM   1932  C C   . ILE A 1 272 ? -8.716  -3.543  -9.963  1.00 28.33  ? 272 ILE A C   1 
ATOM   1933  O O   . ILE A 1 272 ? -9.027  -2.408  -9.593  1.00 33.04  ? 272 ILE A O   1 
ATOM   1934  C CB  . ILE A 1 272 ? -10.581 -4.181  -11.448 1.00 30.83  ? 272 ILE A CB  1 
ATOM   1935  C CG1 . ILE A 1 272 ? -11.758 -5.100  -11.689 1.00 23.59  ? 272 ILE A CG1 1 
ATOM   1936  C CG2 . ILE A 1 272 ? -9.646  -4.130  -12.666 1.00 30.56  ? 272 ILE A CG2 1 
ATOM   1937  C CD1 . ILE A 1 272 ? -12.681 -4.554  -12.771 1.00 32.67  ? 272 ILE A CD1 1 
ATOM   1938  N N   . LEU A 1 273 ? -7.470  -3.896  -10.226 1.00 31.12  ? 273 LEU A N   1 
ATOM   1939  C CA  . LEU A 1 273 ? -6.379  -2.933  -10.153 1.00 36.76  ? 273 LEU A CA  1 
ATOM   1940  C C   . LEU A 1 273 ? -6.201  -2.276  -11.515 1.00 36.75  ? 273 LEU A C   1 
ATOM   1941  O O   . LEU A 1 273 ? -6.041  -2.966  -12.523 1.00 33.83  ? 273 LEU A O   1 
ATOM   1942  C CB  . LEU A 1 273 ? -5.081  -3.605  -9.705  1.00 38.76  ? 273 LEU A CB  1 
ATOM   1943  C CG  . LEU A 1 273 ? -5.199  -4.594  -8.531  1.00 42.02  ? 273 LEU A CG  1 
ATOM   1944  C CD1 . LEU A 1 273 ? -5.634  -6.003  -9.015  1.00 34.03  ? 273 LEU A CD1 1 
ATOM   1945  C CD2 . LEU A 1 273 ? -3.899  -4.672  -7.699  1.00 33.07  ? 273 LEU A CD2 1 
ATOM   1946  N N   . LYS A 1 274 ? -6.248  -0.948  -11.540 1.00 40.77  ? 274 LYS A N   1 
ATOM   1947  C CA  . LYS A 1 274 ? -6.029  -0.173  -12.753 1.00 40.37  ? 274 LYS A CA  1 
ATOM   1948  C C   . LYS A 1 274 ? -4.622  0.403   -12.760 1.00 42.77  ? 274 LYS A C   1 
ATOM   1949  O O   . LYS A 1 274 ? -4.114  0.838   -11.724 1.00 42.96  ? 274 LYS A O   1 
ATOM   1950  C CB  . LYS A 1 274 ? -7.044  0.961   -12.866 1.00 45.10  ? 274 LYS A CB  1 
ATOM   1951  C CG  . LYS A 1 274 ? -8.444  0.578   -12.427 1.00 37.01  ? 274 LYS A CG  1 
ATOM   1952  C CD  . LYS A 1 274 ? -9.111  -0.325  -13.458 1.00 39.10  ? 274 LYS A CD  1 
ATOM   1953  C CE  . LYS A 1 274 ? -9.280  0.366   -14.802 1.00 41.08  ? 274 LYS A CE  1 
ATOM   1954  N NZ  . LYS A 1 274 ? -9.642  1.809   -14.645 1.00 50.97  ? 274 LYS A NZ  1 
ATOM   1955  N N   . TYR A 1 275 ? -4.001  0.401   -13.935 1.00 48.12  ? 275 TYR A N   1 
ATOM   1956  C CA  . TYR A 1 275 ? -2.695  1.002   -14.173 1.00 52.16  ? 275 TYR A CA  1 
ATOM   1957  C C   . TYR A 1 275 ? -2.827  2.061   -15.261 1.00 50.70  ? 275 TYR A C   1 
ATOM   1958  O O   . TYR A 1 275 ? -3.822  2.109   -15.986 1.00 50.74  ? 275 TYR A O   1 
ATOM   1959  C CB  . TYR A 1 275 ? -1.661  -0.062  -14.578 1.00 52.31  ? 275 TYR A CB  1 
ATOM   1960  C CG  . TYR A 1 275 ? -1.564  -1.242  -13.635 1.00 46.57  ? 275 TYR A CG  1 
ATOM   1961  C CD1 . TYR A 1 275 ? -2.480  -2.281  -13.692 1.00 45.01  ? 275 TYR A CD1 1 
ATOM   1962  C CD2 . TYR A 1 275 ? -0.548  -1.315  -12.685 1.00 50.57  ? 275 TYR A CD2 1 
ATOM   1963  C CE1 . TYR A 1 275 ? -2.395  -3.356  -12.825 1.00 46.11  ? 275 TYR A CE1 1 
ATOM   1964  C CE2 . TYR A 1 275 ? -0.452  -2.393  -11.819 1.00 48.16  ? 275 TYR A CE2 1 
ATOM   1965  C CZ  . TYR A 1 275 ? -1.378  -3.403  -11.894 1.00 47.29  ? 275 TYR A CZ  1 
ATOM   1966  O OH  . TYR A 1 275 ? -1.288  -4.470  -11.040 1.00 55.34  ? 275 TYR A OH  1 
ATOM   1967  N N   . GLU A 1 276 ? -1.813  2.914   -15.383 1.00 55.93  ? 276 GLU A N   1 
ATOM   1968  C CA  . GLU A 1 276 ? -1.864  4.007   -16.350 1.00 60.99  ? 276 GLU A CA  1 
ATOM   1969  C C   . GLU A 1 276 ? -1.701  3.444   -17.766 1.00 60.56  ? 276 GLU A C   1 
ATOM   1970  O O   . GLU A 1 276 ? -1.659  2.229   -17.984 1.00 60.64  ? 276 GLU A O   1 
ATOM   1971  C CB  . GLU A 1 276 ? -0.811  5.066   -16.023 1.00 60.32  ? 276 GLU A CB  1 
ATOM   1972  C CG  . GLU A 1 276 ? 0.557   4.518   -15.622 1.00 63.21  ? 276 GLU A CG  1 
ATOM   1973  C CD  . GLU A 1 276 ? 1.676   5.564   -15.694 1.00 63.89  ? 276 GLU A CD  1 
ATOM   1974  O OE1 . GLU A 1 276 ? 1.394   6.731   -16.059 1.00 58.90  ? 276 GLU A OE1 1 
ATOM   1975  O OE2 . GLU A 1 276 ? 2.837   5.215   -15.373 1.00 61.04  ? 276 GLU A OE2 1 
ATOM   1976  N N   . GLN A 1 277 ? -1.612  4.335   -18.755 1.00 66.15  ? 277 GLN A N   1 
ATOM   1977  C CA  . GLN A 1 277 ? -1.424  3.913   -20.150 1.00 66.54  ? 277 GLN A CA  1 
ATOM   1978  C C   . GLN A 1 277 ? -0.142  4.481   -20.758 1.00 65.90  ? 277 GLN A C   1 
ATOM   1979  O O   . GLN A 1 277 ? 0.002   4.548   -21.983 1.00 68.09  ? 277 GLN A O   1 
ATOM   1980  C CB  . GLN A 1 277 ? -2.623  4.328   -21.012 1.00 64.27  ? 277 GLN A CB  1 
ATOM   1981  C CG  . GLN A 1 277 ? -3.938  4.470   -20.264 1.00 60.28  ? 277 GLN A CG  1 
ATOM   1982  C CD  . GLN A 1 277 ? -4.537  3.135   -19.839 1.00 67.65  ? 277 GLN A CD  1 
ATOM   1983  O OE1 . GLN A 1 277 ? -3.994  2.062   -20.131 1.00 71.88  ? 277 GLN A OE1 1 
ATOM   1984  N NE2 . GLN A 1 277 ? -5.678  3.196   -19.158 1.00 54.66  ? 277 GLN A NE2 1 
ATOM   1985  N N   . GLY A 1 284 ? 6.507   -0.471  -20.372 1.00 66.41  ? 284 GLY A N   1 
ATOM   1986  C CA  . GLY A 1 284 ? 7.445   -1.067  -19.443 1.00 65.70  ? 284 GLY A CA  1 
ATOM   1987  C C   . GLY A 1 284 ? 6.935   -1.155  -18.018 1.00 66.60  ? 284 GLY A C   1 
ATOM   1988  O O   . GLY A 1 284 ? 6.897   -2.229  -17.419 1.00 65.41  ? 284 GLY A O   1 
ATOM   1989  N N   . SER A 1 285 ? 6.539   -0.012  -17.463 1.00 72.97  ? 285 SER A N   1 
ATOM   1990  C CA  . SER A 1 285 ? 6.129   0.067   -16.060 1.00 65.16  ? 285 SER A CA  1 
ATOM   1991  C C   . SER A 1 285 ? 4.849   0.894   -15.987 1.00 65.47  ? 285 SER A C   1 
ATOM   1992  O O   . SER A 1 285 ? 4.892   2.129   -15.941 1.00 66.30  ? 285 SER A O   1 
ATOM   1993  C CB  . SER A 1 285 ? 7.238   0.661   -15.206 1.00 62.72  ? 285 SER A CB  1 
ATOM   1994  O OG  . SER A 1 285 ? 8.371   -0.180  -15.246 1.00 59.31  ? 285 SER A OG  1 
ATOM   1995  N N   . ALA A 1 286 ? 3.715   0.203   -15.975 1.00 60.25  ? 286 ALA A N   1 
ATOM   1996  C CA  . ALA A 1 286 ? 2.434   0.854   -15.741 1.00 63.45  ? 286 ALA A CA  1 
ATOM   1997  C C   . ALA A 1 286 ? 2.251   1.088   -14.242 1.00 57.57  ? 286 ALA A C   1 
ATOM   1998  O O   . ALA A 1 286 ? 2.233   0.134   -13.454 1.00 58.36  ? 286 ALA A O   1 
ATOM   1999  C CB  . ALA A 1 286 ? 1.300   0.008   -16.315 1.00 58.05  ? 286 ALA A CB  1 
ATOM   2000  N N   . LYS A 1 287 ? 2.134   2.359   -13.855 1.00 62.65  ? 287 LYS A N   1 
ATOM   2001  C CA  . LYS A 1 287 ? 1.972   2.750   -12.457 1.00 62.03  ? 287 LYS A CA  1 
ATOM   2002  C C   . LYS A 1 287 ? 0.548   2.492   -11.976 1.00 55.80  ? 287 LYS A C   1 
ATOM   2003  O O   . LYS A 1 287 ? -0.425  2.788   -12.679 1.00 53.44  ? 287 LYS A O   1 
ATOM   2004  C CB  . LYS A 1 287 ? 2.314   4.232   -12.276 1.00 59.25  ? 287 LYS A CB  1 
ATOM   2005  C CG  . LYS A 1 287 ? 2.252   4.723   -10.836 1.00 58.98  ? 287 LYS A CG  1 
ATOM   2006  C CD  . LYS A 1 287 ? 2.907   6.089   -10.695 1.00 64.23  ? 287 LYS A CD  1 
ATOM   2007  C CE  . LYS A 1 287 ? 2.716   6.675   -9.299  1.00 67.56  ? 287 LYS A CE  1 
ATOM   2008  N NZ  . LYS A 1 287 ? 1.309   7.087   -8.978  1.00 68.50  ? 287 LYS A NZ  1 
ATOM   2009  N N   . TRP A 1 288 ? 0.436   1.943   -10.764 1.00 55.41  ? 288 TRP A N   1 
ATOM   2010  C CA  . TRP A 1 288 ? -0.863  1.638   -10.166 1.00 46.69  ? 288 TRP A CA  1 
ATOM   2011  C C   . TRP A 1 288 ? -1.601  2.931   -9.849  1.00 47.80  ? 288 TRP A C   1 
ATOM   2012  O O   . TRP A 1 288 ? -1.063  3.795   -9.149  1.00 50.87  ? 288 TRP A O   1 
ATOM   2013  C CB  . TRP A 1 288 ? -0.666  0.813   -8.903  1.00 41.15  ? 288 TRP A CB  1 
ATOM   2014  C CG  . TRP A 1 288 ? -1.937  0.471   -8.193  1.00 46.96  ? 288 TRP A CG  1 
ATOM   2015  C CD1 . TRP A 1 288 ? -3.037  -0.146  -8.728  1.00 48.51  ? 288 TRP A CD1 1 
ATOM   2016  C CD2 . TRP A 1 288 ? -2.248  0.722   -6.813  1.00 34.34  ? 288 TRP A CD2 1 
ATOM   2017  N NE1 . TRP A 1 288 ? -4.014  -0.290  -7.766  1.00 47.05  ? 288 TRP A NE1 1 
ATOM   2018  C CE2 . TRP A 1 288 ? -3.553  0.232   -6.583  1.00 44.06  ? 288 TRP A CE2 1 
ATOM   2019  C CE3 . TRP A 1 288 ? -1.549  1.301   -5.750  1.00 38.75  ? 288 TRP A CE3 1 
ATOM   2020  C CZ2 . TRP A 1 288 ? -4.172  0.311   -5.336  1.00 36.97  ? 288 TRP A CZ2 1 
ATOM   2021  C CZ3 . TRP A 1 288 ? -2.174  1.384   -4.505  1.00 37.17  ? 288 TRP A CZ3 1 
ATOM   2022  C CH2 . TRP A 1 288 ? -3.465  0.890   -4.312  1.00 29.32  ? 288 TRP A CH2 1 
ATOM   2023  N N   . ILE A 1 289 ? -2.827  3.076   -10.352 1.00 40.69  ? 289 ILE A N   1 
ATOM   2024  C CA  . ILE A 1 289 ? -3.537  4.345   -10.245 1.00 41.46  ? 289 ILE A CA  1 
ATOM   2025  C C   . ILE A 1 289 ? -4.871  4.239   -9.524  1.00 39.96  ? 289 ILE A C   1 
ATOM   2026  O O   . ILE A 1 289 ? -5.493  5.284   -9.269  1.00 45.16  ? 289 ILE A O   1 
ATOM   2027  C CB  . ILE A 1 289 ? -3.741  5.012   -11.626 1.00 45.14  ? 289 ILE A CB  1 
ATOM   2028  C CG1 . ILE A 1 289 ? -4.406  4.056   -12.607 1.00 48.41  ? 289 ILE A CG1 1 
ATOM   2029  C CG2 . ILE A 1 289 ? -2.413  5.492   -12.201 1.00 48.88  ? 289 ILE A CG2 1 
ATOM   2030  C CD1 . ILE A 1 289 ? -4.800  4.739   -13.902 1.00 54.29  ? 289 ILE A CD1 1 
ATOM   2031  N N   . GLY A 1 290 ? -5.340  3.046   -9.182  1.00 39.13  ? 290 GLY A N   1 
ATOM   2032  C CA  . GLY A 1 290 ? -6.545  2.938   -8.382  1.00 36.33  ? 290 GLY A CA  1 
ATOM   2033  C C   . GLY A 1 290 ? -7.149  1.550   -8.425  1.00 34.44  ? 290 GLY A C   1 
ATOM   2034  O O   . GLY A 1 290 ? -6.627  0.634   -9.058  1.00 37.40  ? 290 GLY A O   1 
ATOM   2035  N N   . LEU A 1 291 ? -8.269  1.413   -7.717  1.00 29.13  ? 291 LEU A N   1 
ATOM   2036  C CA  . LEU A 1 291 ? -9.056  0.192   -7.721  1.00 31.76  ? 291 LEU A CA  1 
ATOM   2037  C C   . LEU A 1 291 ? -10.450 0.523   -8.231  1.00 34.77  ? 291 LEU A C   1 
ATOM   2038  O O   . LEU A 1 291 ? -10.993 1.591   -7.933  1.00 31.21  ? 291 LEU A O   1 
ATOM   2039  C CB  . LEU A 1 291 ? -9.144  -0.434  -6.327  1.00 29.05  ? 291 LEU A CB  1 
ATOM   2040  C CG  . LEU A 1 291 ? -7.816  -0.982  -5.760  1.00 37.76  ? 291 LEU A CG  1 
ATOM   2041  C CD1 . LEU A 1 291 ? -8.033  -1.998  -4.648  1.00 28.79  ? 291 LEU A CD1 1 
ATOM   2042  C CD2 . LEU A 1 291 ? -6.953  -1.603  -6.839  1.00 37.49  ? 291 LEU A CD2 1 
ATOM   2043  N N   . ASP A 1 292 ? -11.033 -0.392  -9.000  1.00 29.93  ? 292 ASP A N   1 
ATOM   2044  C CA  . ASP A 1 292 ? -12.387 -0.200  -9.486  1.00 30.55  ? 292 ASP A CA  1 
ATOM   2045  C C   . ASP A 1 292 ? -13.413 -1.081  -8.808  1.00 35.46  ? 292 ASP A C   1 
ATOM   2046  O O   . ASP A 1 292 ? -14.568 -0.685  -8.717  1.00 41.66  ? 292 ASP A O   1 
ATOM   2047  C CB  . ASP A 1 292 ? -12.455 -0.437  -10.992 1.00 33.95  ? 292 ASP A CB  1 
ATOM   2048  C CG  . ASP A 1 292 ? -12.104 0.794   -11.774 1.00 35.16  ? 292 ASP A CG  1 
ATOM   2049  O OD1 . ASP A 1 292 ? -11.828 1.827   -11.134 1.00 27.32  ? 292 ASP A OD1 1 
ATOM   2050  O OD2 . ASP A 1 292 ? -12.092 0.725   -13.017 1.00 44.06  ? 292 ASP A OD2 1 
ATOM   2051  N N   . SER A 1 293 ? -13.053 -2.250  -8.340  1.00 33.45  ? 293 SER A N   1 
ATOM   2052  C CA  . SER A 1 293 ? -14.093 -3.074  -7.710  1.00 39.16  ? 293 SER A CA  1 
ATOM   2053  C C   . SER A 1 293 ? -15.351 -3.191  -8.566  1.00 45.41  ? 293 SER A C   1 
ATOM   2054  O O   . SER A 1 293 ? -15.329 -2.824  -9.751  1.00 52.79  ? 293 SER A O   1 
ATOM   2055  C CB  . SER A 1 293 ? -14.491 -2.561  -6.327  1.00 33.74  ? 293 SER A CB  1 
ATOM   2056  O OG  . SER A 1 293 ? -15.232 -3.556  -5.633  1.00 29.17  ? 293 SER A OG  1 
ATOM   2057  N N   . PRO A 1 294 ? -16.488 -3.552  -7.978  1.00 37.99  ? 294 PRO A N   1 
ATOM   2058  C CA  . PRO A 1 294 ? -17.110 -4.799  -8.411  1.00 33.80  ? 294 PRO A CA  1 
ATOM   2059  C C   . PRO A 1 294 ? -16.378 -5.236  -9.665  1.00 34.03  ? 294 PRO A C   1 
ATOM   2060  O O   . PRO A 1 294 ? -16.637 -4.696  -10.748 1.00 34.31  ? 294 PRO A O   1 
ATOM   2061  C CB  . PRO A 1 294 ? -18.576 -4.429  -8.663  1.00 39.85  ? 294 PRO A CB  1 
ATOM   2062  C CG  . PRO A 1 294 ? -18.807 -3.200  -7.957  1.00 32.27  ? 294 PRO A CG  1 
ATOM   2063  C CD  . PRO A 1 294 ? -17.482 -2.484  -7.781  1.00 34.00  ? 294 PRO A CD  1 
ATOM   2064  N N   . SER A 1 295 ? -15.398 -6.128  -9.518  1.00 30.54  ? 295 SER A N   1 
ATOM   2065  C CA  . SER A 1 295 ? -14.720 -6.676  -10.679 1.00 29.41  ? 295 SER A CA  1 
ATOM   2066  C C   . SER A 1 295 ? -15.736 -7.306  -11.628 1.00 29.78  ? 295 SER A C   1 
ATOM   2067  O O   . SER A 1 295 ? -16.901 -7.507  -11.294 1.00 35.34  ? 295 SER A O   1 
ATOM   2068  C CB  . SER A 1 295 ? -13.685 -7.722  -10.264 1.00 30.21  ? 295 SER A CB  1 
ATOM   2069  O OG  . SER A 1 295 ? -14.214 -9.026  -10.440 1.00 23.75  ? 295 SER A OG  1 
ATOM   2070  N N   . ARG A 1 296 ? -15.287 -7.616  -12.835 1.00 32.93  ? 296 ARG A N   1 
ATOM   2071  C CA  . ARG A 1 296 ? -16.123 -8.346  -13.778 1.00 37.50  ? 296 ARG A CA  1 
ATOM   2072  C C   . ARG A 1 296 ? -15.635 -9.777  -13.975 1.00 33.41  ? 296 ARG A C   1 
ATOM   2073  O O   . ARG A 1 296 ? -15.809 -10.356 -15.046 1.00 40.77  ? 296 ARG A O   1 
ATOM   2074  C CB  . ARG A 1 296 ? -16.208 -7.609  -15.113 1.00 41.32  ? 296 ARG A CB  1 
ATOM   2075  C CG  . ARG A 1 296 ? -17.407 -6.634  -15.206 1.00 50.00  ? 296 ARG A CG  1 
ATOM   2076  C CD  . ARG A 1 296 ? -18.751 -7.239  -14.684 1.00 57.19  ? 296 ARG A CD  1 
ATOM   2077  N NE  . ARG A 1 296 ? -19.449 -8.091  -15.648 1.00 66.90  ? 296 ARG A NE  1 
ATOM   2078  C CZ  . ARG A 1 296 ? -19.940 -9.299  -15.384 1.00 63.03  ? 296 ARG A CZ  1 
ATOM   2079  N NH1 . ARG A 1 296 ? -19.827 -9.846  -14.183 1.00 61.99  ? 296 ARG A NH1 1 
ATOM   2080  N NH2 . ARG A 1 296 ? -20.557 -9.977  -16.351 1.00 58.77  ? 296 ARG A NH2 1 
ATOM   2081  N N   . SER A 1 297 ? -15.046 -10.368 -12.939 1.00 30.04  ? 297 SER A N   1 
ATOM   2082  C CA  . SER A 1 297 ? -14.475 -11.701 -13.036 1.00 27.96  ? 297 SER A CA  1 
ATOM   2083  C C   . SER A 1 297 ? -15.022 -12.630 -11.959 1.00 32.27  ? 297 SER A C   1 
ATOM   2084  O O   . SER A 1 297 ? -14.331 -13.547 -11.517 1.00 33.46  ? 297 SER A O   1 
ATOM   2085  C CB  . SER A 1 297 ? -12.949 -11.645 -12.969 1.00 30.48  ? 297 SER A CB  1 
ATOM   2086  O OG  . SER A 1 297 ? -12.433 -10.582 -13.756 1.00 32.64  ? 297 SER A OG  1 
ATOM   2087  N N   . GLU A 1 298 ? -16.264 -12.427 -11.534 1.00 33.25  ? 298 GLU A N   1 
ATOM   2088  C CA  . GLU A 1 298 ? -16.903 -13.351 -10.597 1.00 33.96  ? 298 GLU A CA  1 
ATOM   2089  C C   . GLU A 1 298 ? -17.720 -14.362 -11.388 1.00 31.56  ? 298 GLU A C   1 
ATOM   2090  O O   . GLU A 1 298 ? -18.803 -14.053 -11.888 1.00 41.15  ? 298 GLU A O   1 
ATOM   2091  C CB  . GLU A 1 298 ? -17.777 -12.610 -9.598  1.00 29.15  ? 298 GLU A CB  1 
ATOM   2092  C CG  . GLU A 1 298 ? -16.999 -11.960 -8.492  1.00 29.84  ? 298 GLU A CG  1 
ATOM   2093  C CD  . GLU A 1 298 ? -17.896 -11.245 -7.547  1.00 31.26  ? 298 GLU A CD  1 
ATOM   2094  O OE1 . GLU A 1 298 ? -18.931 -11.848 -7.201  1.00 36.36  ? 298 GLU A OE1 1 
ATOM   2095  O OE2 . GLU A 1 298 ? -17.579 -10.098 -7.149  1.00 31.75  ? 298 GLU A OE2 1 
ATOM   2096  N N   . PHE A 1 299 ? -17.190 -15.572 -11.514 1.00 31.29  ? 299 PHE A N   1 
ATOM   2097  C CA  . PHE A 1 299 ? -17.927 -16.707 -12.048 1.00 33.94  ? 299 PHE A CA  1 
ATOM   2098  C C   . PHE A 1 299 ? -17.146 -17.955 -11.671 1.00 29.35  ? 299 PHE A C   1 
ATOM   2099  O O   . PHE A 1 299 ? -16.082 -17.878 -11.054 1.00 29.90  ? 299 PHE A O   1 
ATOM   2100  C CB  . PHE A 1 299 ? -18.153 -16.607 -13.564 1.00 32.05  ? 299 PHE A CB  1 
ATOM   2101  C CG  . PHE A 1 299 ? -16.995 -16.022 -14.321 1.00 33.50  ? 299 PHE A CG  1 
ATOM   2102  C CD1 . PHE A 1 299 ? -15.915 -16.801 -14.666 1.00 34.83  ? 299 PHE A CD1 1 
ATOM   2103  C CD2 . PHE A 1 299 ? -17.003 -14.691 -14.698 1.00 34.24  ? 299 PHE A CD2 1 
ATOM   2104  C CE1 . PHE A 1 299 ? -14.856 -16.269 -15.370 1.00 36.75  ? 299 PHE A CE1 1 
ATOM   2105  C CE2 . PHE A 1 299 ? -15.956 -14.155 -15.396 1.00 37.87  ? 299 PHE A CE2 1 
ATOM   2106  C CZ  . PHE A 1 299 ? -14.871 -14.948 -15.734 1.00 37.09  ? 299 PHE A CZ  1 
ATOM   2107  N N   . GLU A 1 300 ? -17.673 -19.108 -12.070 1.00 30.17  ? 300 GLU A N   1 
ATOM   2108  C CA  . GLU A 1 300 ? -17.230 -20.360 -11.470 1.00 32.47  ? 300 GLU A CA  1 
ATOM   2109  C C   . GLU A 1 300 ? -15.752 -20.620 -11.732 1.00 29.63  ? 300 GLU A C   1 
ATOM   2110  O O   . GLU A 1 300 ? -15.035 -21.069 -10.833 1.00 31.08  ? 300 GLU A O   1 
ATOM   2111  C CB  . GLU A 1 300 ? -18.091 -21.530 -11.971 1.00 33.87  ? 300 GLU A CB  1 
ATOM   2112  C CG  . GLU A 1 300 ? -17.803 -22.846 -11.229 1.00 36.14  ? 300 GLU A CG  1 
ATOM   2113  C CD  . GLU A 1 300 ? -17.688 -24.054 -12.143 1.00 46.90  ? 300 GLU A CD  1 
ATOM   2114  O OE1 . GLU A 1 300 ? -18.731 -24.530 -12.646 1.00 51.56  ? 300 GLU A OE1 1 
ATOM   2115  O OE2 . GLU A 1 300 ? -16.548 -24.524 -12.367 1.00 53.28  ? 300 GLU A OE2 1 
ATOM   2116  N N   . ALA A 1 301 ? -15.265 -20.328 -12.942 1.00 30.06  ? 301 ALA A N   1 
ATOM   2117  C CA  . ALA A 1 301 ? -13.871 -20.641 -13.248 1.00 28.97  ? 301 ALA A CA  1 
ATOM   2118  C C   . ALA A 1 301 ? -12.874 -19.778 -12.481 1.00 29.16  ? 301 ALA A C   1 
ATOM   2119  O O   . ALA A 1 301 ? -11.675 -20.060 -12.551 1.00 27.08  ? 301 ALA A O   1 
ATOM   2120  C CB  . ALA A 1 301 ? -13.597 -20.502 -14.740 1.00 31.35  ? 301 ALA A CB  1 
ATOM   2121  N N   . THR A 1 302 ? -13.318 -18.719 -11.800 1.00 27.52  ? 302 THR A N   1 
ATOM   2122  C CA  . THR A 1 302 ? -12.449 -17.951 -10.914 1.00 26.28  ? 302 THR A CA  1 
ATOM   2123  C C   . THR A 1 302 ? -12.773 -18.172 -9.447  1.00 25.40  ? 302 THR A C   1 
ATOM   2124  O O   . THR A 1 302 ? -11.874 -18.501 -8.664  1.00 24.89  ? 302 THR A O   1 
ATOM   2125  C CB  . THR A 1 302 ? -12.532 -16.453 -11.220 1.00 29.00  ? 302 THR A CB  1 
ATOM   2126  O OG1 . THR A 1 302 ? -13.899 -16.032 -11.146 1.00 27.93  ? 302 THR A OG1 1 
ATOM   2127  C CG2 . THR A 1 302 ? -11.932 -16.134 -12.611 1.00 26.47  ? 302 THR A CG2 1 
ATOM   2128  N N   . LEU A 1 303 ? -14.055 -18.020 -9.075  1.00 25.87  ? 303 LEU A N   1 
ATOM   2129  C CA  . LEU A 1 303 ? -14.485 -18.092 -7.679  1.00 26.14  ? 303 LEU A CA  1 
ATOM   2130  C C   . LEU A 1 303 ? -14.132 -19.428 -7.044  1.00 23.65  ? 303 LEU A C   1 
ATOM   2131  O O   . LEU A 1 303 ? -13.749 -19.509 -5.869  1.00 22.99  ? 303 LEU A O   1 
ATOM   2132  C CB  . LEU A 1 303 ? -16.002 -17.876 -7.601  1.00 27.12  ? 303 LEU A CB  1 
ATOM   2133  C CG  . LEU A 1 303 ? -16.454 -16.455 -7.967  1.00 28.91  ? 303 LEU A CG  1 
ATOM   2134  C CD1 . LEU A 1 303 ? -17.955 -16.409 -8.193  1.00 27.15  ? 303 LEU A CD1 1 
ATOM   2135  C CD2 . LEU A 1 303 ? -16.043 -15.499 -6.864  1.00 26.42  ? 303 LEU A CD2 1 
ATOM   2136  N N   . LYS A 1 304 ? -14.262 -20.460 -7.790  1.00 25.55  ? 304 LYS A N   1 
ATOM   2137  C CA  . LYS A 1 304 ? -14.382 -21.782 -7.238  1.00 22.84  ? 304 LYS A CA  1 
ATOM   2138  C C   . LYS A 1 304 ? -12.996 -22.411 -7.057  1.00 26.46  ? 304 LYS A C   1 
ATOM   2139  O O   . LYS A 1 304 ? -12.722 -22.954 -5.975  1.00 26.43  ? 304 LYS A O   1 
ATOM   2140  C CB  . LYS A 1 304 ? -15.399 -22.467 -8.153  1.00 33.55  ? 304 LYS A CB  1 
ATOM   2141  C CG  . LYS A 1 304 ? -15.424 -23.878 -8.325  1.00 33.83  ? 304 LYS A CG  1 
ATOM   2142  C CD  . LYS A 1 304 ? -15.355 -24.647 -7.088  1.00 43.29  ? 304 LYS A CD  1 
ATOM   2143  C CE  . LYS A 1 304 ? -14.715 -25.908 -7.584  1.00 51.93  ? 304 LYS A CE  1 
ATOM   2144  N NZ  . LYS A 1 304 ? -14.562 -26.977 -6.633  1.00 50.65  ? 304 LYS A NZ  1 
ATOM   2145  N N   . PRO A 1 305 ? -12.057 -22.270 -8.006  1.00 26.90  ? 305 PRO A N   1 
ATOM   2146  C CA  . PRO A 1 305 ? -10.647 -22.559 -7.662  1.00 24.91  ? 305 PRO A CA  1 
ATOM   2147  C C   . PRO A 1 305 ? -10.080 -21.612 -6.615  1.00 24.12  ? 305 PRO A C   1 
ATOM   2148  O O   . PRO A 1 305 ? -9.268  -22.033 -5.782  1.00 24.12  ? 305 PRO A O   1 
ATOM   2149  C CB  . PRO A 1 305 ? -9.901  -22.410 -8.999  1.00 21.69  ? 305 PRO A CB  1 
ATOM   2150  C CG  . PRO A 1 305 ? -10.805 -21.665 -9.871  1.00 25.23  ? 305 PRO A CG  1 
ATOM   2151  C CD  . PRO A 1 305 ? -12.208 -21.961 -9.434  1.00 23.88  ? 305 PRO A CD  1 
ATOM   2152  N N   . ALA A 1 306 ? -10.469 -20.339 -6.620  1.00 23.16  ? 306 ALA A N   1 
ATOM   2153  C CA  . ALA A 1 306 ? -9.958  -19.457 -5.574  1.00 25.82  ? 306 ALA A CA  1 
ATOM   2154  C C   . ALA A 1 306 ? -10.482 -19.879 -4.201  1.00 21.14  ? 306 ALA A C   1 
ATOM   2155  O O   . ALA A 1 306 ? -9.723  -19.879 -3.223  1.00 19.82  ? 306 ALA A O   1 
ATOM   2156  C CB  . ALA A 1 306 ? -10.310 -18.004 -5.885  1.00 21.21  ? 306 ALA A CB  1 
ATOM   2157  N N   . GLU A 1 307 ? -11.766 -20.264 -4.118  1.00 17.86  ? 307 GLU A N   1 
ATOM   2158  C CA  . GLU A 1 307 ? -12.328 -20.790 -2.873  1.00 23.92  ? 307 GLU A CA  1 
ATOM   2159  C C   . GLU A 1 307 ? -11.550 -22.004 -2.379  1.00 24.92  ? 307 GLU A C   1 
ATOM   2160  O O   . GLU A 1 307 ? -11.244 -22.117 -1.184  1.00 18.25  ? 307 GLU A O   1 
ATOM   2161  C CB  . GLU A 1 307 ? -13.808 -21.176 -3.056  1.00 24.53  ? 307 GLU A CB  1 
ATOM   2162  C CG  . GLU A 1 307 ? -14.553 -21.435 -1.728  1.00 27.70  ? 307 GLU A CG  1 
ATOM   2163  C CD  . GLU A 1 307 ? -15.938 -22.096 -1.909  1.00 38.97  ? 307 GLU A CD  1 
ATOM   2164  O OE1 . GLU A 1 307 ? -16.533 -21.989 -3.004  1.00 40.84  ? 307 GLU A OE1 1 
ATOM   2165  O OE2 . GLU A 1 307 ? -16.455 -22.697 -0.940  1.00 36.67  ? 307 GLU A OE2 1 
ATOM   2166  N N   . GLU A 1 308 ? -11.255 -22.946 -3.285  1.00 20.66  ? 308 GLU A N   1 
ATOM   2167  C CA  . GLU A 1 308 ? -10.537 -24.141 -2.871  1.00 25.96  ? 308 GLU A CA  1 
ATOM   2168  C C   . GLU A 1 308 ? -9.173  -23.775 -2.306  1.00 20.78  ? 308 GLU A C   1 
ATOM   2169  O O   . GLU A 1 308 ? -8.737  -24.337 -1.294  1.00 19.42  ? 308 GLU A O   1 
ATOM   2170  C CB  . GLU A 1 308 ? -10.387 -25.123 -4.040  1.00 22.48  ? 308 GLU A CB  1 
ATOM   2171  C CG  . GLU A 1 308 ? -9.446  -26.246 -3.669  1.00 27.09  ? 308 GLU A CG  1 
ATOM   2172  C CD  . GLU A 1 308 ? -9.514  -27.467 -4.576  1.00 32.90  ? 308 GLU A CD  1 
ATOM   2173  O OE1 . GLU A 1 308 ? -8.890  -27.407 -5.651  1.00 36.76  ? 308 GLU A OE1 1 
ATOM   2174  O OE2 . GLU A 1 308 ? -10.125 -28.497 -4.201  1.00 36.06  ? 308 GLU A OE2 1 
ATOM   2175  N N   . PHE A 1 309 ? -8.493  -22.816 -2.932  1.00 20.38  ? 309 PHE A N   1 
ATOM   2176  C CA  . PHE A 1 309 ? -7.155  -22.480 -2.474  1.00 20.68  ? 309 PHE A CA  1 
ATOM   2177  C C   . PHE A 1 309 ? -7.204  -21.772 -1.122  1.00 22.56  ? 309 PHE A C   1 
ATOM   2178  O O   . PHE A 1 309 ? -6.425  -22.098 -0.219  1.00 18.81  ? 309 PHE A O   1 
ATOM   2179  C CB  . PHE A 1 309 ? -6.425  -21.637 -3.516  1.00 21.76  ? 309 PHE A CB  1 
ATOM   2180  C CG  . PHE A 1 309 ? -5.002  -21.389 -3.158  1.00 21.44  ? 309 PHE A CG  1 
ATOM   2181  C CD1 . PHE A 1 309 ? -4.654  -20.315 -2.348  1.00 21.44  ? 309 PHE A CD1 1 
ATOM   2182  C CD2 . PHE A 1 309 ? -4.022  -22.274 -3.552  1.00 21.97  ? 309 PHE A CD2 1 
ATOM   2183  C CE1 . PHE A 1 309 ? -3.338  -20.115 -1.970  1.00 26.29  ? 309 PHE A CE1 1 
ATOM   2184  C CE2 . PHE A 1 309 ? -2.695  -22.071 -3.187  1.00 23.82  ? 309 PHE A CE2 1 
ATOM   2185  C CZ  . PHE A 1 309 ? -2.353  -20.994 -2.400  1.00 22.64  ? 309 PHE A CZ  1 
ATOM   2186  N N   . ILE A 1 310 ? -8.134  -20.816 -0.960  1.00 22.43  ? 310 ILE A N   1 
ATOM   2187  C CA  . ILE A 1 310 ? -8.278  -20.100 0.313   1.00 19.75  ? 310 ILE A CA  1 
ATOM   2188  C C   . ILE A 1 310 ? -8.702  -21.050 1.433   1.00 23.38  ? 310 ILE A C   1 
ATOM   2189  O O   . ILE A 1 310 ? -8.206  -20.958 2.566   1.00 23.09  ? 310 ILE A O   1 
ATOM   2190  C CB  . ILE A 1 310 ? -9.260  -18.929 0.148   1.00 20.48  ? 310 ILE A CB  1 
ATOM   2191  C CG1 . ILE A 1 310 ? -8.712  -17.941 -0.876  1.00 26.55  ? 310 ILE A CG1 1 
ATOM   2192  C CG2 . ILE A 1 310 ? -9.557  -18.215 1.508   1.00 20.61  ? 310 ILE A CG2 1 
ATOM   2193  C CD1 . ILE A 1 310 ? -7.280  -17.483 -0.588  1.00 20.64  ? 310 ILE A CD1 1 
ATOM   2194  N N   . GLU A 1 311 ? -9.614  -21.985 1.145   1.00 22.82  ? 311 GLU A N   1 
ATOM   2195  C CA  . GLU A 1 311 ? -9.978  -22.950 2.182   1.00 26.25  ? 311 GLU A CA  1 
ATOM   2196  C C   . GLU A 1 311 ? -8.770  -23.766 2.641   1.00 25.99  ? 311 GLU A C   1 
ATOM   2197  O O   . GLU A 1 311 ? -8.727  -24.207 3.797   1.00 24.39  ? 311 GLU A O   1 
ATOM   2198  C CB  . GLU A 1 311 ? -11.095 -23.871 1.689   1.00 24.51  ? 311 GLU A CB  1 
ATOM   2199  C CG  . GLU A 1 311 ? -11.772 -24.720 2.793   1.00 30.03  ? 311 GLU A CG  1 
ATOM   2200  C CD  . GLU A 1 311 ? -12.193 -23.917 4.032   1.00 35.47  ? 311 GLU A CD  1 
ATOM   2201  O OE1 . GLU A 1 311 ? -13.055 -23.014 3.919   1.00 30.56  ? 311 GLU A OE1 1 
ATOM   2202  O OE2 . GLU A 1 311 ? -11.661 -24.206 5.128   1.00 38.64  ? 311 GLU A OE2 1 
ATOM   2203  N N   . MET A 1 312 ? -7.774  -23.966 1.764   1.00 20.45  ? 312 MET A N   1 
ATOM   2204  C CA  . MET A 1 312 ? -6.574  -24.678 2.182   1.00 20.50  ? 312 MET A CA  1 
ATOM   2205  C C   . MET A 1 312 ? -5.636  -23.797 2.993   1.00 24.73  ? 312 MET A C   1 
ATOM   2206  O O   . MET A 1 312 ? -4.989  -24.294 3.928   1.00 23.37  ? 312 MET A O   1 
ATOM   2207  C CB  . MET A 1 312 ? -5.817  -25.241 0.980   1.00 22.23  ? 312 MET A CB  1 
ATOM   2208  C CG  . MET A 1 312 ? -4.324  -25.328 1.222   1.00 32.62  ? 312 MET A CG  1 
ATOM   2209  S SD  . MET A 1 312 ? -3.475  -26.275 -0.022  1.00 44.36  ? 312 MET A SD  1 
ATOM   2210  C CE  . MET A 1 312 ? -2.825  -24.877 -0.940  1.00 30.42  ? 312 MET A CE  1 
ATOM   2211  N N   . ILE A 1 313 ? -5.532  -22.497 2.682   1.00 21.03  ? 313 ILE A N   1 
ATOM   2212  C CA  . ILE A 1 313 ? -4.725  -21.690 3.591   1.00 23.54  ? 313 ILE A CA  1 
ATOM   2213  C C   . ILE A 1 313 ? -5.445  -21.546 4.932   1.00 24.65  ? 313 ILE A C   1 
ATOM   2214  O O   . ILE A 1 313 ? -4.799  -21.522 5.988   1.00 22.78  ? 313 ILE A O   1 
ATOM   2215  C CB  . ILE A 1 313 ? -4.346  -20.323 2.990   1.00 30.70  ? 313 ILE A CB  1 
ATOM   2216  C CG1 . ILE A 1 313 ? -5.401  -19.288 3.270   1.00 29.14  ? 313 ILE A CG1 1 
ATOM   2217  C CG2 . ILE A 1 313 ? -4.065  -20.394 1.512   1.00 27.42  ? 313 ILE A CG2 1 
ATOM   2218  C CD1 . ILE A 1 313 ? -4.888  -18.276 4.230   1.00 26.97  ? 313 ILE A CD1 1 
ATOM   2219  N N   . ARG A 1 314 ? -6.785  -21.505 4.929   1.00 21.27  ? 314 ARG A N   1 
ATOM   2220  C CA  . ARG A 1 314 ? -7.501  -21.571 6.196   1.00 25.94  ? 314 ARG A CA  1 
ATOM   2221  C C   . ARG A 1 314 ? -7.190  -22.878 6.929   1.00 24.04  ? 314 ARG A C   1 
ATOM   2222  O O   . ARG A 1 314 ? -6.902  -22.868 8.126   1.00 23.47  ? 314 ARG A O   1 
ATOM   2223  C CB  . ARG A 1 314 ? -9.009  -21.414 5.976   1.00 22.65  ? 314 ARG A CB  1 
ATOM   2224  C CG  . ARG A 1 314 ? -9.789  -21.251 7.286   1.00 22.02  ? 314 ARG A CG  1 
ATOM   2225  C CD  . ARG A 1 314 ? -11.267 -20.881 7.064   1.00 20.46  ? 314 ARG A CD  1 
ATOM   2226  N NE  . ARG A 1 314 ? -12.097 -22.078 6.988   1.00 25.43  ? 314 ARG A NE  1 
ATOM   2227  C CZ  . ARG A 1 314 ? -12.552 -22.758 8.037   1.00 25.73  ? 314 ARG A CZ  1 
ATOM   2228  N NH1 . ARG A 1 314 ? -12.353 -22.338 9.277   1.00 28.70  ? 314 ARG A NH1 1 
ATOM   2229  N NH2 . ARG A 1 314 ? -13.231 -23.881 7.835   1.00 31.67  ? 314 ARG A NH2 1 
ATOM   2230  N N   . THR A 1 315 ? -7.209  -24.007 6.219   1.00 24.37  ? 315 THR A N   1 
ATOM   2231  C CA  . THR A 1 315 ? -6.877  -25.288 6.850   1.00 21.87  ? 315 THR A CA  1 
ATOM   2232  C C   . THR A 1 315 ? -5.472  -25.288 7.466   1.00 22.89  ? 315 THR A C   1 
ATOM   2233  O O   . THR A 1 315 ? -5.256  -25.864 8.531   1.00 26.00  ? 315 THR A O   1 
ATOM   2234  C CB  . THR A 1 315 ? -6.993  -26.406 5.830   1.00 19.09  ? 315 THR A CB  1 
ATOM   2235  O OG1 . THR A 1 315 ? -8.312  -26.430 5.316   1.00 22.69  ? 315 THR A OG1 1 
ATOM   2236  C CG2 . THR A 1 315 ? -6.688  -27.755 6.457   1.00 20.45  ? 315 THR A CG2 1 
ATOM   2237  N N   . ILE A 1 316 ? -4.488  -24.678 6.813   1.00 24.70  ? 316 ILE A N   1 
ATOM   2238  C CA  . ILE A 1 316 ? -3.175  -24.731 7.445   1.00 23.59  ? 316 ILE A CA  1 
ATOM   2239  C C   . ILE A 1 316 ? -3.072  -23.789 8.639   1.00 27.46  ? 316 ILE A C   1 
ATOM   2240  O O   . ILE A 1 316 ? -2.069  -23.833 9.358   1.00 20.17  ? 316 ILE A O   1 
ATOM   2241  C CB  . ILE A 1 316 ? -2.020  -24.467 6.459   1.00 27.03  ? 316 ILE A CB  1 
ATOM   2242  C CG1 . ILE A 1 316 ? -1.827  -22.999 6.163   1.00 31.51  ? 316 ILE A CG1 1 
ATOM   2243  C CG2 . ILE A 1 316 ? -2.204  -25.232 5.145   1.00 28.42  ? 316 ILE A CG2 1 
ATOM   2244  C CD1 . ILE A 1 316 ? -0.329  -22.653 6.036   1.00 27.37  ? 316 ILE A CD1 1 
ATOM   2245  N N   . GLY A 1 317 ? -4.078  -22.948 8.897   1.00 27.92  ? 317 GLY A N   1 
ATOM   2246  C CA  . GLY A 1 317 ? -4.142  -22.235 10.170  1.00 23.86  ? 317 GLY A CA  1 
ATOM   2247  C C   . GLY A 1 317 ? -4.154  -20.724 10.109  1.00 25.45  ? 317 GLY A C   1 
ATOM   2248  O O   . GLY A 1 317 ? -4.230  -20.082 11.170  1.00 23.48  ? 317 GLY A O   1 
ATOM   2249  N N   . TYR A 1 318 ? -4.080  -20.108 8.934   1.00 24.80  ? 318 TYR A N   1 
ATOM   2250  C CA  . TYR A 1 318 ? -4.055  -18.659 8.872   1.00 19.33  ? 318 TYR A CA  1 
ATOM   2251  C C   . TYR A 1 318 ? -5.402  -18.081 9.289   1.00 22.66  ? 318 TYR A C   1 
ATOM   2252  O O   . TYR A 1 318 ? -6.465  -18.624 8.966   1.00 20.87  ? 318 TYR A O   1 
ATOM   2253  C CB  . TYR A 1 318 ? -3.710  -18.184 7.462   1.00 24.35  ? 318 TYR A CB  1 
ATOM   2254  C CG  . TYR A 1 318 ? -3.801  -16.677 7.377   1.00 23.95  ? 318 TYR A CG  1 
ATOM   2255  C CD1 . TYR A 1 318 ? -2.883  -15.888 8.038   1.00 18.93  ? 318 TYR A CD1 1 
ATOM   2256  C CD2 . TYR A 1 318 ? -4.859  -16.048 6.724   1.00 21.37  ? 318 TYR A CD2 1 
ATOM   2257  C CE1 . TYR A 1 318 ? -2.976  -14.515 8.009   1.00 24.34  ? 318 TYR A CE1 1 
ATOM   2258  C CE2 . TYR A 1 318 ? -4.953  -14.661 6.682   1.00 19.13  ? 318 TYR A CE2 1 
ATOM   2259  C CZ  . TYR A 1 318 ? -4.009  -13.903 7.337   1.00 24.21  ? 318 TYR A CZ  1 
ATOM   2260  O OH  . TYR A 1 318 ? -4.070  -12.516 7.340   1.00 25.63  ? 318 TYR A OH  1 
ATOM   2261  N N   . ARG A 1 319 ? -5.356  -16.964 10.005  1.00 23.97  ? 319 ARG A N   1 
ATOM   2262  C CA  . ARG A 1 319 ? -6.559  -16.277 10.459  1.00 22.18  ? 319 ARG A CA  1 
ATOM   2263  C C   . ARG A 1 319 ? -6.389  -14.798 10.154  1.00 19.20  ? 319 ARG A C   1 
ATOM   2264  O O   . ARG A 1 319 ? -5.416  -14.186 10.593  1.00 18.99  ? 319 ARG A O   1 
ATOM   2265  C CB  . ARG A 1 319 ? -6.797  -16.503 11.966  1.00 22.78  ? 319 ARG A CB  1 
ATOM   2266  C CG  . ARG A 1 319 ? -6.906  -17.977 12.402  1.00 22.66  ? 319 ARG A CG  1 
ATOM   2267  C CD  . ARG A 1 319 ? -8.193  -18.582 11.868  1.00 24.62  ? 319 ARG A CD  1 
ATOM   2268  N NE  . ARG A 1 319 ? -8.393  -19.982 12.222  1.00 23.31  ? 319 ARG A NE  1 
ATOM   2269  C CZ  . ARG A 1 319 ? -8.059  -21.026 11.473  1.00 25.60  ? 319 ARG A CZ  1 
ATOM   2270  N NH1 . ARG A 1 319 ? -7.376  -20.888 10.342  1.00 24.42  ? 319 ARG A NH1 1 
ATOM   2271  N NH2 . ARG A 1 319 ? -8.412  -22.247 11.875  1.00 22.65  ? 319 ARG A NH2 1 
ATOM   2272  N N   . GLY A 1 320 ? -7.325  -14.215 9.417   1.00 23.27  ? 320 GLY A N   1 
ATOM   2273  C CA  . GLY A 1 320 ? -7.254  -12.801 9.127   1.00 18.93  ? 320 GLY A CA  1 
ATOM   2274  C C   . GLY A 1 320 ? -7.646  -12.555 7.694   1.00 19.28  ? 320 GLY A C   1 
ATOM   2275  O O   . GLY A 1 320 ? -8.263  -13.416 7.073   1.00 19.29  ? 320 GLY A O   1 
ATOM   2276  N N   . TYR A 1 321 ? -7.239  -11.394 7.165   1.00 17.68  ? 321 TYR A N   1 
ATOM   2277  C CA  . TYR A 1 321 ? -7.539  -10.997 5.790   1.00 20.38  ? 321 TYR A CA  1 
ATOM   2278  C C   . TYR A 1 321 ? -6.495  -11.549 4.841   1.00 14.99  ? 321 TYR A C   1 
ATOM   2279  O O   . TYR A 1 321 ? -5.322  -11.613 5.176   1.00 19.50  ? 321 TYR A O   1 
ATOM   2280  C CB  . TYR A 1 321 ? -7.615  -9.470  5.658   1.00 17.38  ? 321 TYR A CB  1 
ATOM   2281  C CG  . TYR A 1 321 ? -8.742  -8.956  6.516   1.00 18.32  ? 321 TYR A CG  1 
ATOM   2282  C CD1 . TYR A 1 321 ? -10.055 -8.995  6.061   1.00 16.71  ? 321 TYR A CD1 1 
ATOM   2283  C CD2 . TYR A 1 321 ? -8.505  -8.508  7.794   1.00 16.20  ? 321 TYR A CD2 1 
ATOM   2284  C CE1 . TYR A 1 321 ? -11.097 -8.562  6.848   1.00 21.01  ? 321 TYR A CE1 1 
ATOM   2285  C CE2 . TYR A 1 321 ? -9.540  -8.077  8.596   1.00 21.15  ? 321 TYR A CE2 1 
ATOM   2286  C CZ  . TYR A 1 321 ? -10.831 -8.105  8.115   1.00 23.12  ? 321 TYR A CZ  1 
ATOM   2287  O OH  . TYR A 1 321 ? -11.861 -7.690  8.903   1.00 27.50  ? 321 TYR A OH  1 
ATOM   2288  N N   . VAL A 1 322 ? -6.943  -12.007 3.679   1.00 18.24  ? 322 VAL A N   1 
ATOM   2289  C CA  . VAL A 1 322 ? -6.061  -12.586 2.676   1.00 19.91  ? 322 VAL A CA  1 
ATOM   2290  C C   . VAL A 1 322 ? -6.695  -12.334 1.325   1.00 19.48  ? 322 VAL A C   1 
ATOM   2291  O O   . VAL A 1 322 ? -7.912  -12.463 1.169   1.00 19.92  ? 322 VAL A O   1 
ATOM   2292  C CB  . VAL A 1 322 ? -5.810  -14.094 2.924   1.00 20.04  ? 322 VAL A CB  1 
ATOM   2293  C CG1 . VAL A 1 322 ? -7.093  -14.879 2.858   1.00 23.72  ? 322 VAL A CG1 1 
ATOM   2294  C CG2 . VAL A 1 322 ? -4.819  -14.659 1.917   1.00 21.79  ? 322 VAL A CG2 1 
ATOM   2295  N N   . ASN A 1 323 ? -5.872  -11.965 0.348   1.00 18.29  ? 323 ASN A N   1 
ATOM   2296  C CA  . ASN A 1 323 ? -6.362  -11.748 -0.999  1.00 21.53  ? 323 ASN A CA  1 
ATOM   2297  C C   . ASN A 1 323 ? -5.542  -12.571 -1.980  1.00 25.03  ? 323 ASN A C   1 
ATOM   2298  O O   . ASN A 1 323 ? -4.352  -12.816 -1.766  1.00 20.23  ? 323 ASN A O   1 
ATOM   2299  C CB  . ASN A 1 323 ? -6.341  -10.247 -1.356  1.00 20.61  ? 323 ASN A CB  1 
ATOM   2300  C CG  . ASN A 1 323 ? -4.932  -9.660  -1.385  1.00 30.34  ? 323 ASN A CG  1 
ATOM   2301  O OD1 . ASN A 1 323 ? -4.219  -9.824  -2.367  1.00 31.52  ? 323 ASN A OD1 1 
ATOM   2302  N ND2 . ASN A 1 323 ? -4.541  -8.935  -0.319  1.00 25.70  ? 323 ASN A ND2 1 
ATOM   2303  N N   . ILE A 1 324 ? -6.209  -13.030 -3.044  1.00 23.51  ? 324 ILE A N   1 
ATOM   2304  C CA  . ILE A 1 324 ? -5.588  -13.799 -4.116  1.00 20.99  ? 324 ILE A CA  1 
ATOM   2305  C C   . ILE A 1 324 ? -5.904  -13.097 -5.428  1.00 27.84  ? 324 ILE A C   1 
ATOM   2306  O O   . ILE A 1 324 ? -7.069  -12.791 -5.709  1.00 23.13  ? 324 ILE A O   1 
ATOM   2307  C CB  . ILE A 1 324 ? -6.074  -15.262 -4.133  1.00 23.98  ? 324 ILE A CB  1 
ATOM   2308  C CG1 . ILE A 1 324 ? -5.361  -16.054 -5.230  1.00 25.41  ? 324 ILE A CG1 1 
ATOM   2309  C CG2 . ILE A 1 324 ? -7.598  -15.355 -4.293  1.00 23.00  ? 324 ILE A CG2 1 
ATOM   2310  C CD1 . ILE A 1 324 ? -5.664  -17.535 -5.222  1.00 19.95  ? 324 ILE A CD1 1 
ATOM   2311  N N   . ASP A 1 325 ? -4.876  -12.776 -6.202  1.00 25.22  ? 325 ASP A N   1 
ATOM   2312  C CA  . ASP A 1 325 ? -5.141  -12.080 -7.448  1.00 28.09  ? 325 ASP A CA  1 
ATOM   2313  C C   . ASP A 1 325 ? -4.888  -12.991 -8.645  1.00 26.88  ? 325 ASP A C   1 
ATOM   2314  O O   . ASP A 1 325 ? -4.183  -14.004 -8.553  1.00 26.51  ? 325 ASP A O   1 
ATOM   2315  C CB  . ASP A 1 325 ? -4.353  -10.763 -7.535  1.00 22.88  ? 325 ASP A CB  1 
ATOM   2316  C CG  . ASP A 1 325 ? -2.851  -10.942 -7.692  1.00 36.91  ? 325 ASP A CG  1 
ATOM   2317  O OD1 . ASP A 1 325 ? -2.366  -12.043 -8.042  1.00 39.52  ? 325 ASP A OD1 1 
ATOM   2318  O OD2 . ASP A 1 325 ? -2.141  -9.932  -7.462  1.00 43.10  ? 325 ASP A OD2 1 
ATOM   2319  N N   . GLY A 1 326 ? -5.507  -12.626 -9.761  1.00 22.17  ? 326 GLY A N   1 
ATOM   2320  C CA  . GLY A 1 326 ? -5.440  -13.435 -10.951 1.00 26.76  ? 326 GLY A CA  1 
ATOM   2321  C C   . GLY A 1 326 ? -5.778  -12.644 -12.191 1.00 27.69  ? 326 GLY A C   1 
ATOM   2322  O O   . GLY A 1 326 ? -5.850  -11.414 -12.170 1.00 22.82  ? 326 GLY A O   1 
ATOM   2323  N N   . ILE A 1 327 ? -5.986  -13.383 -13.285 1.00 30.47  ? 327 ILE A N   1 
ATOM   2324  C CA  . ILE A 1 327 ? -6.326  -12.805 -14.579 1.00 29.44  ? 327 ILE A CA  1 
ATOM   2325  C C   . ILE A 1 327 ? -7.192  -13.787 -15.343 1.00 29.49  ? 327 ILE A C   1 
ATOM   2326  O O   . ILE A 1 327 ? -7.185  -14.994 -15.088 1.00 27.74  ? 327 ILE A O   1 
ATOM   2327  C CB  . ILE A 1 327 ? -5.090  -12.461 -15.449 1.00 25.94  ? 327 ILE A CB  1 
ATOM   2328  C CG1 . ILE A 1 327 ? -4.318  -13.734 -15.775 1.00 30.18  ? 327 ILE A CG1 1 
ATOM   2329  C CG2 . ILE A 1 327 ? -4.178  -11.454 -14.777 1.00 28.46  ? 327 ILE A CG2 1 
ATOM   2330  C CD1 . ILE A 1 327 ? -3.434  -13.588 -16.986 1.00 34.28  ? 327 ILE A CD1 1 
ATOM   2331  N N   . VAL A 1 328 ? -7.920  -13.245 -16.312 1.00 28.14  ? 328 VAL A N   1 
ATOM   2332  C CA  . VAL A 1 328 ? -8.657  -13.986 -17.324 1.00 30.31  ? 328 VAL A CA  1 
ATOM   2333  C C   . VAL A 1 328 ? -8.112  -13.553 -18.674 1.00 35.42  ? 328 VAL A C   1 
ATOM   2334  O O   . VAL A 1 328 ? -8.067  -12.351 -18.965 1.00 34.12  ? 328 VAL A O   1 
ATOM   2335  C CB  . VAL A 1 328 ? -10.170 -13.699 -17.248 1.00 30.13  ? 328 VAL A CB  1 
ATOM   2336  C CG1 . VAL A 1 328 ? -10.959 -14.738 -18.032 1.00 29.82  ? 328 VAL A CG1 1 
ATOM   2337  C CG2 . VAL A 1 328 ? -10.645 -13.611 -15.765 1.00 29.56  ? 328 VAL A CG2 1 
ATOM   2338  N N   . LEU A 1 329 ? -7.698  -14.517 -19.494 1.00 31.11  ? 329 LEU A N   1 
ATOM   2339  C CA  . LEU A 1 329 ? -7.339  -14.177 -20.867 1.00 38.36  ? 329 LEU A CA  1 
ATOM   2340  C C   . LEU A 1 329 ? -8.581  -14.075 -21.754 1.00 38.39  ? 329 LEU A C   1 
ATOM   2341  O O   . LEU A 1 329 ? -9.643  -14.623 -21.452 1.00 41.23  ? 329 LEU A O   1 
ATOM   2342  C CB  . LEU A 1 329 ? -6.371  -15.197 -21.457 1.00 35.00  ? 329 LEU A CB  1 
ATOM   2343  C CG  . LEU A 1 329 ? -5.069  -15.374 -20.685 1.00 36.25  ? 329 LEU A CG  1 
ATOM   2344  C CD1 . LEU A 1 329 ? -4.186  -16.410 -21.353 1.00 34.80  ? 329 LEU A CD1 1 
ATOM   2345  C CD2 . LEU A 1 329 ? -4.348  -14.045 -20.573 1.00 40.94  ? 329 LEU A CD2 1 
ATOM   2346  N N   . ASP A 1 330 ? -8.426  -13.371 -22.880 1.00 45.60  ? 330 ASP A N   1 
ATOM   2347  C CA  . ASP A 1 330 ? -9.519  -13.234 -23.840 1.00 45.56  ? 330 ASP A CA  1 
ATOM   2348  C C   . ASP A 1 330 ? -9.977  -14.566 -24.423 1.00 46.03  ? 330 ASP A C   1 
ATOM   2349  O O   . ASP A 1 330 ? -11.011 -14.594 -25.098 1.00 47.70  ? 330 ASP A O   1 
ATOM   2350  C CB  . ASP A 1 330 ? -9.124  -12.283 -24.975 1.00 49.34  ? 330 ASP A CB  1 
ATOM   2351  C CG  . ASP A 1 330 ? -7.686  -12.466 -25.426 1.00 58.89  ? 330 ASP A CG  1 
ATOM   2352  O OD1 . ASP A 1 330 ? -7.470  -12.656 -26.645 1.00 68.37  ? 330 ASP A OD1 1 
ATOM   2353  O OD2 . ASP A 1 330 ? -6.770  -12.396 -24.569 1.00 59.59  ? 330 ASP A OD2 1 
ATOM   2354  N N   . ASP A 1 331 ? -9.252  -15.662 -24.184 1.00 42.64  ? 331 ASP A N   1 
ATOM   2355  C CA  . ASP A 1 331 ? -9.720  -16.998 -24.531 1.00 42.62  ? 331 ASP A CA  1 
ATOM   2356  C C   . ASP A 1 331 ? -10.347 -17.726 -23.342 1.00 44.80  ? 331 ASP A C   1 
ATOM   2357  O O   . ASP A 1 331 ? -10.644 -18.923 -23.441 1.00 39.06  ? 331 ASP A O   1 
ATOM   2358  C CB  . ASP A 1 331 ? -8.575  -17.823 -25.144 1.00 46.96  ? 331 ASP A CB  1 
ATOM   2359  C CG  . ASP A 1 331 ? -7.509  -18.246 -24.124 1.00 47.22  ? 331 ASP A CG  1 
ATOM   2360  O OD1 . ASP A 1 331 ? -7.527  -17.754 -22.974 1.00 42.15  ? 331 ASP A OD1 1 
ATOM   2361  O OD2 . ASP A 1 331 ? -6.619  -19.052 -24.499 1.00 40.73  ? 331 ASP A OD2 1 
ATOM   2362  N N   . GLY A 1 332 ? -10.554 -17.029 -22.222 1.00 45.61  ? 332 GLY A N   1 
ATOM   2363  C CA  . GLY A 1 332 ? -11.242 -17.592 -21.076 1.00 42.86  ? 332 GLY A CA  1 
ATOM   2364  C C   . GLY A 1 332 ? -10.374 -18.328 -20.076 1.00 38.30  ? 332 GLY A C   1 
ATOM   2365  O O   . GLY A 1 332 ? -10.898 -18.827 -19.079 1.00 39.77  ? 332 GLY A O   1 
ATOM   2366  N N   . ARG A 1 333 ? -9.070  -18.419 -20.299 1.00 38.44  ? 333 ARG A N   1 
ATOM   2367  C CA  . ARG A 1 333 ? -8.217  -19.134 -19.359 1.00 39.98  ? 333 ARG A CA  1 
ATOM   2368  C C   . ARG A 1 333 ? -7.959  -18.276 -18.125 1.00 36.22  ? 333 ARG A C   1 
ATOM   2369  O O   . ARG A 1 333 ? -7.735  -17.062 -18.218 1.00 31.27  ? 333 ARG A O   1 
ATOM   2370  C CB  . ARG A 1 333 ? -6.894  -19.538 -20.013 1.00 33.04  ? 333 ARG A CB  1 
ATOM   2371  C CG  . ARG A 1 333 ? -6.881  -20.969 -20.572 1.00 35.36  ? 333 ARG A CG  1 
ATOM   2372  C CD  . ARG A 1 333 ? -5.556  -21.296 -21.244 1.00 38.16  ? 333 ARG A CD  1 
ATOM   2373  N NE  . ARG A 1 333 ? -5.200  -20.344 -22.292 1.00 30.83  ? 333 ARG A NE  1 
ATOM   2374  C CZ  . ARG A 1 333 ? -3.956  -20.040 -22.637 1.00 35.05  ? 333 ARG A CZ  1 
ATOM   2375  N NH1 . ARG A 1 333 ? -2.912  -20.580 -22.019 1.00 30.49  ? 333 ARG A NH1 1 
ATOM   2376  N NH2 . ARG A 1 333 ? -3.753  -19.166 -23.623 1.00 35.54  ? 333 ARG A NH2 1 
ATOM   2377  N N   . VAL A 1 334 ? -8.005  -18.922 -16.966 1.00 33.72  ? 334 VAL A N   1 
ATOM   2378  C CA  . VAL A 1 334 ? -7.817  -18.274 -15.677 1.00 31.37  ? 334 VAL A CA  1 
ATOM   2379  C C   . VAL A 1 334 ? -6.467  -18.689 -15.108 1.00 29.75  ? 334 VAL A C   1 
ATOM   2380  O O   . VAL A 1 334 ? -6.093  -19.863 -15.167 1.00 32.39  ? 334 VAL A O   1 
ATOM   2381  C CB  . VAL A 1 334 ? -8.959  -18.650 -14.718 1.00 34.42  ? 334 VAL A CB  1 
ATOM   2382  C CG1 . VAL A 1 334 ? -8.580  -18.328 -13.268 1.00 27.85  ? 334 VAL A CG1 1 
ATOM   2383  C CG2 . VAL A 1 334 ? -10.259 -17.957 -15.158 1.00 31.20  ? 334 VAL A CG2 1 
ATOM   2384  N N   . PHE A 1 335 ? -5.739  -17.723 -14.566 1.00 30.36  ? 335 PHE A N   1 
ATOM   2385  C CA  . PHE A 1 335 ? -4.499  -17.943 -13.835 1.00 28.29  ? 335 PHE A CA  1 
ATOM   2386  C C   . PHE A 1 335 ? -4.537  -17.118 -12.560 1.00 27.34  ? 335 PHE A C   1 
ATOM   2387  O O   . PHE A 1 335 ? -5.006  -15.979 -12.574 1.00 31.70  ? 335 PHE A O   1 
ATOM   2388  C CB  . PHE A 1 335 ? -3.271  -17.520 -14.645 1.00 26.04  ? 335 PHE A CB  1 
ATOM   2389  C CG  . PHE A 1 335 ? -3.029  -18.341 -15.875 1.00 32.02  ? 335 PHE A CG  1 
ATOM   2390  C CD1 . PHE A 1 335 ? -2.774  -19.698 -15.782 1.00 28.60  ? 335 PHE A CD1 1 
ATOM   2391  C CD2 . PHE A 1 335 ? -3.045  -17.750 -17.130 1.00 34.07  ? 335 PHE A CD2 1 
ATOM   2392  C CE1 . PHE A 1 335 ? -2.540  -20.454 -16.923 1.00 31.06  ? 335 PHE A CE1 1 
ATOM   2393  C CE2 . PHE A 1 335 ? -2.805  -18.500 -18.279 1.00 34.97  ? 335 PHE A CE2 1 
ATOM   2394  C CZ  . PHE A 1 335 ? -2.544  -19.845 -18.178 1.00 30.78  ? 335 PHE A CZ  1 
ATOM   2395  N N   . PHE A 1 336 ? -4.024  -17.670 -11.469 1.00 25.82  ? 336 PHE A N   1 
ATOM   2396  C CA  . PHE A 1 336 ? -3.824  -16.930 -10.232 1.00 28.11  ? 336 PHE A CA  1 
ATOM   2397  C C   . PHE A 1 336 ? -2.338  -16.677 -10.030 1.00 29.43  ? 336 PHE A C   1 
ATOM   2398  O O   . PHE A 1 336 ? -1.527  -17.593 -10.194 1.00 26.59  ? 336 PHE A O   1 
ATOM   2399  C CB  . PHE A 1 336 ? -4.410  -17.695 -9.047  1.00 25.00  ? 336 PHE A CB  1 
ATOM   2400  C CG  . PHE A 1 336 ? -5.883  -17.882 -9.145  1.00 25.38  ? 336 PHE A CG  1 
ATOM   2401  C CD1 . PHE A 1 336 ? -6.752  -16.860 -8.765  1.00 24.67  ? 336 PHE A CD1 1 
ATOM   2402  C CD2 . PHE A 1 336 ? -6.408  -19.062 -9.644  1.00 26.34  ? 336 PHE A CD2 1 
ATOM   2403  C CE1 . PHE A 1 336 ? -8.123  -17.022 -8.864  1.00 23.23  ? 336 PHE A CE1 1 
ATOM   2404  C CE2 . PHE A 1 336 ? -7.760  -19.237 -9.755  1.00 22.07  ? 336 PHE A CE2 1 
ATOM   2405  C CZ  . PHE A 1 336 ? -8.632  -18.216 -9.358  1.00 27.67  ? 336 PHE A CZ  1 
ATOM   2406  N N   . HIS A 1 337 ? -1.984  -15.439 -9.672  1.00 29.23  ? 337 HIS A N   1 
ATOM   2407  C CA  . HIS A 1 337 ? -0.582  -15.029 -9.604  1.00 28.69  ? 337 HIS A CA  1 
ATOM   2408  C C   . HIS A 1 337 ? -0.007  -15.063 -8.193  1.00 35.05  ? 337 HIS A C   1 
ATOM   2409  O O   . HIS A 1 337 ? 1.092   -15.589 -8.002  1.00 28.97  ? 337 HIS A O   1 
ATOM   2410  C CB  . HIS A 1 337 ? -0.392  -13.620 -10.177 1.00 29.16  ? 337 HIS A CB  1 
ATOM   2411  C CG  . HIS A 1 337 ? -0.773  -13.494 -11.618 1.00 38.67  ? 337 HIS A CG  1 
ATOM   2412  N ND1 . HIS A 1 337 ? -0.559  -14.503 -12.538 1.00 39.82  ? 337 HIS A ND1 1 
ATOM   2413  C CD2 . HIS A 1 337 ? -1.325  -12.465 -12.308 1.00 34.02  ? 337 HIS A CD2 1 
ATOM   2414  C CE1 . HIS A 1 337 ? -0.983  -14.108 -13.727 1.00 31.80  ? 337 HIS A CE1 1 
ATOM   2415  N NE2 . HIS A 1 337 ? -1.456  -12.877 -13.614 1.00 34.24  ? 337 HIS A NE2 1 
ATOM   2416  N N   . GLU A 1 338 ? -0.693  -14.477 -7.201  1.00 31.58  ? 338 GLU A N   1 
ATOM   2417  C CA  . GLU A 1 338 ? -0.140  -14.458 -5.854  1.00 26.58  ? 338 GLU A CA  1 
ATOM   2418  C C   . GLU A 1 338 ? -1.234  -14.384 -4.796  1.00 27.24  ? 338 GLU A C   1 
ATOM   2419  O O   . GLU A 1 338 ? -2.408  -14.151 -5.088  1.00 25.75  ? 338 GLU A O   1 
ATOM   2420  C CB  . GLU A 1 338 ? 0.858   -13.310 -5.676  1.00 29.79  ? 338 GLU A CB  1 
ATOM   2421  C CG  . GLU A 1 338 ? 0.693   -12.139 -6.563  1.00 33.12  ? 338 GLU A CG  1 
ATOM   2422  C CD  . GLU A 1 338 ? 1.692   -11.028 -6.216  1.00 41.13  ? 338 GLU A CD  1 
ATOM   2423  O OE1 . GLU A 1 338 ? 1.506   -10.365 -5.166  1.00 39.13  ? 338 GLU A OE1 1 
ATOM   2424  O OE2 . GLU A 1 338 ? 2.657   -10.811 -6.995  1.00 38.93  ? 338 GLU A OE2 1 
ATOM   2425  N N   . ILE A 1 339 ? -0.826  -14.635 -3.549  1.00 25.61  ? 339 ILE A N   1 
ATOM   2426  C CA  . ILE A 1 339 ? -1.630  -14.327 -2.374  1.00 26.53  ? 339 ILE A CA  1 
ATOM   2427  C C   . ILE A 1 339 ? -0.873  -13.340 -1.498  1.00 27.69  ? 339 ILE A C   1 
ATOM   2428  O O   . ILE A 1 339 ? 0.353   -13.201 -1.570  1.00 24.47  ? 339 ILE A O   1 
ATOM   2429  C CB  . ILE A 1 339 ? -1.996  -15.565 -1.542  1.00 18.79  ? 339 ILE A CB  1 
ATOM   2430  C CG1 . ILE A 1 339 ? -0.718  -16.338 -1.194  1.00 25.71  ? 339 ILE A CG1 1 
ATOM   2431  C CG2 . ILE A 1 339 ? -3.039  -16.384 -2.252  1.00 22.01  ? 339 ILE A CG2 1 
ATOM   2432  C CD1 . ILE A 1 339 ? -0.938  -17.505 -0.233  1.00 26.87  ? 339 ILE A CD1 1 
ATOM   2433  N N   . ASN A 1 340 ? -1.632  -12.652 -0.657  1.00 25.92  ? 340 ASN A N   1 
ATOM   2434  C CA  . ASN A 1 340 ? -1.082  -11.748 0.349   1.00 25.96  ? 340 ASN A CA  1 
ATOM   2435  C C   . ASN A 1 340 ? -1.904  -11.951 1.613   1.00 24.13  ? 340 ASN A C   1 
ATOM   2436  O O   . ASN A 1 340 ? -3.084  -11.591 1.643   1.00 22.85  ? 340 ASN A O   1 
ATOM   2437  C CB  . ASN A 1 340 ? -1.138  -10.289 -0.121  1.00 31.65  ? 340 ASN A CB  1 
ATOM   2438  C CG  . ASN A 1 340 ? -0.474  -10.080 -1.475  1.00 33.46  ? 340 ASN A CG  1 
ATOM   2439  O OD1 . ASN A 1 340 ? -1.124  -9.690  -2.442  1.00 34.82  ? 340 ASN A OD1 1 
ATOM   2440  N ND2 . ASN A 1 340 ? 0.821   -10.346 -1.547  1.00 33.91  ? 340 ASN A ND2 1 
ATOM   2441  N N   . ALA A 1 341 ? -1.298  -12.559 2.634   1.00 21.97  ? 341 ALA A N   1 
ATOM   2442  C CA  . ALA A 1 341 ? -1.914  -12.698 3.959   1.00 23.87  ? 341 ALA A CA  1 
ATOM   2443  C C   . ALA A 1 341 ? -1.710  -11.400 4.754   1.00 24.78  ? 341 ALA A C   1 
ATOM   2444  O O   . ALA A 1 341 ? -0.831  -11.278 5.614   1.00 21.56  ? 341 ALA A O   1 
ATOM   2445  C CB  . ALA A 1 341 ? -1.342  -13.907 4.686   1.00 19.49  ? 341 ALA A CB  1 
ATOM   2446  N N   . ARG A 1 342 ? -2.551  -10.402 4.439   1.00 26.48  ? 342 ARG A N   1 
ATOM   2447  C CA  . ARG A 1 342 ? -2.545  -9.076  5.058   1.00 24.02  ? 342 ARG A CA  1 
ATOM   2448  C C   . ARG A 1 342 ? -3.710  -8.270  4.502   1.00 20.12  ? 342 ARG A C   1 
ATOM   2449  O O   . ARG A 1 342 ? -4.427  -8.777  3.638   1.00 18.58  ? 342 ARG A O   1 
ATOM   2450  C CB  . ARG A 1 342 ? -1.231  -8.343  4.800   1.00 23.32  ? 342 ARG A CB  1 
ATOM   2451  C CG  . ARG A 1 342 ? -0.715  -8.458  3.390   1.00 28.06  ? 342 ARG A CG  1 
ATOM   2452  C CD  . ARG A 1 342 ? 0.614   -7.706  3.237   1.00 35.05  ? 342 ARG A CD  1 
ATOM   2453  N NE  . ARG A 1 342 ? 0.750   -7.204  1.880   1.00 44.39  ? 342 ARG A NE  1 
ATOM   2454  C CZ  . ARG A 1 342 ? 1.301   -7.883  0.883   1.00 49.94  ? 342 ARG A CZ  1 
ATOM   2455  N NH1 . ARG A 1 342 ? 1.926   -9.034  1.090   1.00 46.40  ? 342 ARG A NH1 1 
ATOM   2456  N NH2 . ARG A 1 342 ? 1.210   -7.403  -0.358  1.00 54.41  ? 342 ARG A NH2 1 
ATOM   2457  N N   . TRP A 1 343 ? -3.903  -7.022  4.951   1.00 20.35  ? 343 TRP A N   1 
ATOM   2458  C CA  . TRP A 1 343 ? -4.928  -6.182  4.332   1.00 23.86  ? 343 TRP A CA  1 
ATOM   2459  C C   . TRP A 1 343 ? -4.597  -5.962  2.867   1.00 22.73  ? 343 TRP A C   1 
ATOM   2460  O O   . TRP A 1 343 ? -3.467  -5.617  2.529   1.00 23.81  ? 343 TRP A O   1 
ATOM   2461  C CB  . TRP A 1 343 ? -5.037  -4.810  5.006   1.00 20.84  ? 343 TRP A CB  1 
ATOM   2462  C CG  . TRP A 1 343 ? -5.479  -4.824  6.415   1.00 19.62  ? 343 TRP A CG  1 
ATOM   2463  C CD1 . TRP A 1 343 ? -6.135  -5.812  7.056   1.00 21.37  ? 343 TRP A CD1 1 
ATOM   2464  C CD2 . TRP A 1 343 ? -5.284  -3.779  7.364   1.00 19.46  ? 343 TRP A CD2 1 
ATOM   2465  N NE1 . TRP A 1 343 ? -6.362  -5.456  8.359   1.00 25.09  ? 343 TRP A NE1 1 
ATOM   2466  C CE2 . TRP A 1 343 ? -5.847  -4.204  8.571   1.00 24.14  ? 343 TRP A CE2 1 
ATOM   2467  C CE3 . TRP A 1 343 ? -4.674  -2.524  7.306   1.00 18.90  ? 343 TRP A CE3 1 
ATOM   2468  C CZ2 . TRP A 1 343 ? -5.809  -3.427  9.727   1.00 19.63  ? 343 TRP A CZ2 1 
ATOM   2469  C CZ3 . TRP A 1 343 ? -4.651  -1.752  8.435   1.00 23.37  ? 343 TRP A CZ3 1 
ATOM   2470  C CH2 . TRP A 1 343 ? -5.202  -2.208  9.637   1.00 22.55  ? 343 TRP A CH2 1 
ATOM   2471  N N   . SER A 1 344 ? -5.581  -6.154  1.990   1.00 22.50  ? 344 SER A N   1 
ATOM   2472  C CA  . SER A 1 344 ? -5.406  -5.583  0.667   1.00 18.65  ? 344 SER A CA  1 
ATOM   2473  C C   . SER A 1 344 ? -5.461  -4.059  0.771   1.00 22.81  ? 344 SER A C   1 
ATOM   2474  O O   . SER A 1 344 ? -5.967  -3.498  1.747   1.00 25.19  ? 344 SER A O   1 
ATOM   2475  C CB  . SER A 1 344 ? -6.469  -6.100  -0.297  1.00 21.72  ? 344 SER A CB  1 
ATOM   2476  O OG  . SER A 1 344 ? -7.577  -5.224  -0.360  1.00 21.81  ? 344 SER A OG  1 
ATOM   2477  N N   . GLY A 1 345 ? -4.881  -3.380  -0.220  1.00 19.26  ? 345 GLY A N   1 
ATOM   2478  C CA  . GLY A 1 345 ? -5.093  -1.948  -0.321  1.00 20.53  ? 345 GLY A CA  1 
ATOM   2479  C C   . GLY A 1 345 ? -6.548  -1.562  -0.548  1.00 20.70  ? 345 GLY A C   1 
ATOM   2480  O O   . GLY A 1 345 ? -6.916  -0.404  -0.327  1.00 22.24  ? 345 GLY A O   1 
ATOM   2481  N N   . GLY A 1 346 ? -7.385  -2.507  -0.984  1.00 24.29  ? 346 GLY A N   1 
ATOM   2482  C CA  . GLY A 1 346 ? -8.797  -2.274  -1.220  1.00 20.12  ? 346 GLY A CA  1 
ATOM   2483  C C   . GLY A 1 346 ? -9.736  -2.695  -0.106  1.00 21.50  ? 346 GLY A C   1 
ATOM   2484  O O   . GLY A 1 346 ? -10.954 -2.528  -0.248  1.00 21.22  ? 346 GLY A O   1 
ATOM   2485  N N   . LEU A 1 347 ? -9.214  -3.229  1.005   1.00 17.03  ? 347 LEU A N   1 
ATOM   2486  C CA  . LEU A 1 347 ? -10.095 -3.645  2.092   1.00 20.98  ? 347 LEU A CA  1 
ATOM   2487  C C   . LEU A 1 347 ? -10.828 -2.456  2.703   1.00 18.48  ? 347 LEU A C   1 
ATOM   2488  O O   . LEU A 1 347 ? -11.987 -2.593  3.103   1.00 18.52  ? 347 LEU A O   1 
ATOM   2489  C CB  . LEU A 1 347 ? -9.312  -4.408  3.166   1.00 17.97  ? 347 LEU A CB  1 
ATOM   2490  C CG  . LEU A 1 347 ? -10.107 -4.783  4.417   1.00 20.24  ? 347 LEU A CG  1 
ATOM   2491  C CD1 . LEU A 1 347 ? -11.273 -5.716  4.069   1.00 19.34  ? 347 LEU A CD1 1 
ATOM   2492  C CD2 . LEU A 1 347 ? -9.213  -5.407  5.490   1.00 16.10  ? 347 LEU A CD2 1 
ATOM   2493  N N   . ILE A 1 348 ? -10.168 -1.293  2.800   1.00 21.35  ? 348 ILE A N   1 
ATOM   2494  C CA  . ILE A 1 348 ? -10.821 -0.098  3.343   1.00 18.53  ? 348 ILE A CA  1 
ATOM   2495  C C   . ILE A 1 348 ? -11.901 0.425   2.389   1.00 21.15  ? 348 ILE A C   1 
ATOM   2496  O O   . ILE A 1 348 ? -12.964 0.882   2.834   1.00 22.43  ? 348 ILE A O   1 
ATOM   2497  C CB  . ILE A 1 348 ? -9.772  0.979   3.685   1.00 17.72  ? 348 ILE A CB  1 
ATOM   2498  C CG1 . ILE A 1 348 ? -10.397 2.125   4.467   1.00 16.00  ? 348 ILE A CG1 1 
ATOM   2499  C CG2 . ILE A 1 348 ? -9.014  1.497   2.442   1.00 21.07  ? 348 ILE A CG2 1 
ATOM   2500  C CD1 . ILE A 1 348 ? -10.812 1.716   5.885   1.00 17.14  ? 348 ILE A CD1 1 
ATOM   2501  N N   . TYR A 1 349 ? -11.655 0.378   1.072   1.00 18.29  ? 349 TYR A N   1 
ATOM   2502  C CA  . TYR A 1 349 ? -12.690 0.779   0.110   1.00 18.11  ? 349 TYR A CA  1 
ATOM   2503  C C   . TYR A 1 349 ? -13.959 -0.011  0.334   1.00 20.65  ? 349 TYR A C   1 
ATOM   2504  O O   . TYR A 1 349 ? -15.057 0.545   0.347   1.00 20.50  ? 349 TYR A O   1 
ATOM   2505  C CB  . TYR A 1 349 ? -12.222 0.535   -1.333  1.00 19.74  ? 349 TYR A CB  1 
ATOM   2506  C CG  . TYR A 1 349 ? -10.969 1.260   -1.746  1.00 21.63  ? 349 TYR A CG  1 
ATOM   2507  C CD1 . TYR A 1 349 ? -10.534 2.370   -1.053  1.00 21.41  ? 349 TYR A CD1 1 
ATOM   2508  C CD2 . TYR A 1 349 ? -10.229 0.830   -2.830  1.00 24.19  ? 349 TYR A CD2 1 
ATOM   2509  C CE1 . TYR A 1 349 ? -9.395  3.026   -1.410  1.00 23.75  ? 349 TYR A CE1 1 
ATOM   2510  C CE2 . TYR A 1 349 ? -9.083  1.488   -3.208  1.00 25.68  ? 349 TYR A CE2 1 
ATOM   2511  C CZ  . TYR A 1 349 ? -8.681  2.597   -2.495  1.00 24.60  ? 349 TYR A CZ  1 
ATOM   2512  O OH  . TYR A 1 349 ? -7.548  3.269   -2.853  1.00 27.22  ? 349 TYR A OH  1 
ATOM   2513  N N   . HIS A 1 350 ? -13.816 -1.341  0.406   1.00 21.77  ? 350 HIS A N   1 
ATOM   2514  C CA  . HIS A 1 350 ? -14.927 -2.234  0.694   1.00 21.43  ? 350 HIS A CA  1 
ATOM   2515  C C   . HIS A 1 350 ? -15.540 -1.923  2.056   1.00 21.22  ? 350 HIS A C   1 
ATOM   2516  O O   . HIS A 1 350 ? -16.767 -1.918  2.203   1.00 21.75  ? 350 HIS A O   1 
ATOM   2517  C CB  . HIS A 1 350 ? -14.434 -3.688  0.615   1.00 18.25  ? 350 HIS A CB  1 
ATOM   2518  C CG  . HIS A 1 350 ? -15.370 -4.681  1.217   1.00 20.08  ? 350 HIS A CG  1 
ATOM   2519  N ND1 . HIS A 1 350 ? -16.512 -5.114  0.576   1.00 24.45  ? 350 HIS A ND1 1 
ATOM   2520  C CD2 . HIS A 1 350 ? -15.343 -5.319  2.410   1.00 17.75  ? 350 HIS A CD2 1 
ATOM   2521  C CE1 . HIS A 1 350 ? -17.146 -5.984  1.344   1.00 20.82  ? 350 HIS A CE1 1 
ATOM   2522  N NE2 . HIS A 1 350 ? -16.457 -6.127  2.462   1.00 21.77  ? 350 HIS A NE2 1 
ATOM   2523  N N   . THR A 1 351 ? -14.701 -1.603  3.045   1.00 22.35  ? 351 THR A N   1 
ATOM   2524  C CA  . THR A 1 351 ? -15.186 -1.251  4.380   1.00 20.14  ? 351 THR A CA  1 
ATOM   2525  C C   . THR A 1 351 ? -16.050 0.004   4.366   1.00 22.43  ? 351 THR A C   1 
ATOM   2526  O O   . THR A 1 351 ? -17.094 0.054   5.028   1.00 24.68  ? 351 THR A O   1 
ATOM   2527  C CB  . THR A 1 351 ? -14.004 -1.038  5.320   1.00 22.93  ? 351 THR A CB  1 
ATOM   2528  O OG1 . THR A 1 351 ? -13.174 -2.193  5.287   1.00 21.41  ? 351 THR A OG1 1 
ATOM   2529  C CG2 . THR A 1 351 ? -14.485 -0.763  6.749   1.00 17.71  ? 351 THR A CG2 1 
ATOM   2530  N N   . VAL A 1 352 ? -15.618 1.060   3.675   1.00 22.20  ? 352 VAL A N   1 
ATOM   2531  C CA  . VAL A 1 352 ? -16.507 2.218   3.732   1.00 22.03  ? 352 VAL A CA  1 
ATOM   2532  C C   . VAL A 1 352 ? -17.697 2.026   2.804   1.00 22.22  ? 352 VAL A C   1 
ATOM   2533  O O   . VAL A 1 352 ? -18.789 2.517   3.096   1.00 24.24  ? 352 VAL A O   1 
ATOM   2534  C CB  . VAL A 1 352 ? -15.805 3.563   3.467   1.00 25.98  ? 352 VAL A CB  1 
ATOM   2535  C CG1 . VAL A 1 352 ? -14.328 3.477   3.613   1.00 19.61  ? 352 VAL A CG1 1 
ATOM   2536  C CG2 . VAL A 1 352 ? -16.233 4.151   2.148   1.00 26.26  ? 352 VAL A CG2 1 
ATOM   2537  N N   . ALA A 1 353 ? -17.534 1.291   1.706   1.00 23.61  ? 353 ALA A N   1 
ATOM   2538  C CA  . ALA A 1 353 ? -18.688 0.982   0.867   1.00 18.85  ? 353 ALA A CA  1 
ATOM   2539  C C   . ALA A 1 353 ? -19.765 0.270   1.671   1.00 20.71  ? 353 ALA A C   1 
ATOM   2540  O O   . ALA A 1 353 ? -20.954 0.610   1.574   1.00 17.68  ? 353 ALA A O   1 
ATOM   2541  C CB  . ALA A 1 353 ? -18.257 0.136   -0.337  1.00 18.91  ? 353 ALA A CB  1 
ATOM   2542  N N   . GLU A 1 354 ? -19.362 -0.701  2.494   1.00 18.64  ? 354 GLU A N   1 
ATOM   2543  C CA  . GLU A 1 354 ? -20.327 -1.471  3.276   1.00 23.85  ? 354 GLU A CA  1 
ATOM   2544  C C   . GLU A 1 354 ? -20.975 -0.628  4.360   1.00 24.29  ? 354 GLU A C   1 
ATOM   2545  O O   . GLU A 1 354 ? -22.149 -0.838  4.689   1.00 23.75  ? 354 GLU A O   1 
ATOM   2546  C CB  . GLU A 1 354 ? -19.651 -2.685  3.914   1.00 25.95  ? 354 GLU A CB  1 
ATOM   2547  C CG  . GLU A 1 354 ? -20.622 -3.680  4.504   1.00 30.81  ? 354 GLU A CG  1 
ATOM   2548  C CD  . GLU A 1 354 ? -19.948 -4.993  4.911   1.00 32.83  ? 354 GLU A CD  1 
ATOM   2549  O OE1 . GLU A 1 354 ? -18.863 -4.941  5.530   1.00 34.90  ? 354 GLU A OE1 1 
ATOM   2550  O OE2 . GLU A 1 354 ? -20.498 -6.073  4.600   1.00 36.34  ? 354 GLU A OE2 1 
ATOM   2551  N N   . ARG A 1 355 ? -20.208 0.286   4.968   1.00 20.36  ? 355 ARG A N   1 
ATOM   2552  C CA  . ARG A 1 355 ? -20.735 1.114   6.047   1.00 23.57  ? 355 ARG A CA  1 
ATOM   2553  C C   . ARG A 1 355 ? -21.649 2.231   5.548   1.00 26.29  ? 355 ARG A C   1 
ATOM   2554  O O   . ARG A 1 355 ? -22.594 2.602   6.252   1.00 27.10  ? 355 ARG A O   1 
ATOM   2555  C CB  . ARG A 1 355 ? -19.592 1.718   6.848   1.00 21.24  ? 355 ARG A CB  1 
ATOM   2556  C CG  . ARG A 1 355 ? -18.815 0.669   7.591   1.00 27.52  ? 355 ARG A CG  1 
ATOM   2557  C CD  . ARG A 1 355 ? -17.703 1.278   8.360   1.00 23.76  ? 355 ARG A CD  1 
ATOM   2558  N NE  . ARG A 1 355 ? -18.196 1.895   9.578   1.00 21.46  ? 355 ARG A NE  1 
ATOM   2559  C CZ  . ARG A 1 355 ? -17.395 2.400   10.496  1.00 24.13  ? 355 ARG A CZ  1 
ATOM   2560  N NH1 . ARG A 1 355 ? -16.078 2.351   10.355  1.00 25.35  ? 355 ARG A NH1 1 
ATOM   2561  N NH2 . ARG A 1 355 ? -17.922 2.999   11.561  1.00 24.44  ? 355 ARG A NH2 1 
ATOM   2562  N N   . LEU A 1 356 ? -21.393 2.781   4.362   1.00 20.63  ? 356 LEU A N   1 
ATOM   2563  C CA  . LEU A 1 356 ? -22.231 3.865   3.863   1.00 25.53  ? 356 LEU A CA  1 
ATOM   2564  C C   . LEU A 1 356 ? -23.409 3.361   3.042   1.00 24.66  ? 356 LEU A C   1 
ATOM   2565  O O   . LEU A 1 356 ? -24.464 4.003   3.018   1.00 26.80  ? 356 LEU A O   1 
ATOM   2566  C CB  . LEU A 1 356 ? -21.385 4.835   3.028   1.00 22.45  ? 356 LEU A CB  1 
ATOM   2567  C CG  . LEU A 1 356 ? -20.295 5.528   3.850   1.00 24.22  ? 356 LEU A CG  1 
ATOM   2568  C CD1 . LEU A 1 356 ? -19.476 6.519   3.014   1.00 25.57  ? 356 LEU A CD1 1 
ATOM   2569  C CD2 . LEU A 1 356 ? -20.901 6.234   5.043   1.00 29.44  ? 356 LEU A CD2 1 
ATOM   2570  N N   . LEU A 1 357 ? -23.261 2.214   2.386   1.00 25.76  ? 357 LEU A N   1 
ATOM   2571  C CA  . LEU A 1 357 ? -24.253 1.720   1.457   1.00 20.95  ? 357 LEU A CA  1 
ATOM   2572  C C   . LEU A 1 357 ? -24.857 0.401   1.878   1.00 24.25  ? 357 LEU A C   1 
ATOM   2573  O O   . LEU A 1 357 ? -25.822 -0.046  1.242   1.00 22.78  ? 357 LEU A O   1 
ATOM   2574  C CB  . LEU A 1 357 ? -23.644 1.565   0.054   1.00 23.24  ? 357 LEU A CB  1 
ATOM   2575  C CG  . LEU A 1 357 ? -23.116 2.886   -0.514  1.00 23.67  ? 357 LEU A CG  1 
ATOM   2576  C CD1 . LEU A 1 357 ? -22.604 2.729   -1.924  1.00 22.81  ? 357 LEU A CD1 1 
ATOM   2577  C CD2 . LEU A 1 357 ? -24.195 3.972   -0.434  1.00 24.28  ? 357 LEU A CD2 1 
ATOM   2578  N N   . GLY A 1 358 ? -24.330 -0.234  2.920   1.00 20.93  ? 358 GLY A N   1 
ATOM   2579  C CA  . GLY A 1 358 ? -24.881 -1.492  3.374   1.00 22.73  ? 358 GLY A CA  1 
ATOM   2580  C C   . GLY A 1 358 ? -24.163 -2.695  2.779   1.00 24.55  ? 358 GLY A C   1 
ATOM   2581  O O   . GLY A 1 358 ? -23.494 -2.619  1.750   1.00 23.88  ? 358 GLY A O   1 
ATOM   2582  N N   . HIS A 1 359 ? -24.311 -3.827  3.474   1.00 22.42  ? 359 HIS A N   1 
ATOM   2583  C CA  . HIS A 1 359 ? -23.625 -5.057  3.103   1.00 26.87  ? 359 HIS A CA  1 
ATOM   2584  C C   . HIS A 1 359 ? -23.878 -5.460  1.654   1.00 25.63  ? 359 HIS A C   1 
ATOM   2585  O O   . HIS A 1 359 ? -23.010 -6.068  1.011   1.00 26.99  ? 359 HIS A O   1 
ATOM   2586  C CB  . HIS A 1 359 ? -24.063 -6.160  4.067   1.00 25.85  ? 359 HIS A CB  1 
ATOM   2587  C CG  . HIS A 1 359 ? -25.467 -6.638  3.858   1.00 27.32  ? 359 HIS A CG  1 
ATOM   2588  N ND1 . HIS A 1 359 ? -25.801 -7.586  2.914   1.00 21.64  ? 359 HIS A ND1 1 
ATOM   2589  C CD2 . HIS A 1 359 ? -26.616 -6.337  4.514   1.00 23.74  ? 359 HIS A CD2 1 
ATOM   2590  C CE1 . HIS A 1 359 ? -27.097 -7.821  2.974   1.00 25.61  ? 359 HIS A CE1 1 
ATOM   2591  N NE2 . HIS A 1 359 ? -27.616 -7.074  3.932   1.00 21.32  ? 359 HIS A NE2 1 
ATOM   2592  N N   . ASP A 1 360 ? -25.045 -5.120  1.124   1.00 21.63  ? 360 ASP A N   1 
ATOM   2593  C CA  . ASP A 1 360 ? -25.497 -5.499  -0.211  1.00 28.76  ? 360 ASP A CA  1 
ATOM   2594  C C   . ASP A 1 360 ? -24.901 -4.647  -1.327  1.00 29.21  ? 360 ASP A C   1 
ATOM   2595  O O   . ASP A 1 360 ? -25.273 -4.869  -2.484  1.00 32.62  ? 360 ASP A O   1 
ATOM   2596  C CB  . ASP A 1 360 ? -27.033 -5.378  -0.271  1.00 33.33  ? 360 ASP A CB  1 
ATOM   2597  C CG  . ASP A 1 360 ? -27.658 -6.216  -1.361  1.00 42.59  ? 360 ASP A CG  1 
ATOM   2598  O OD1 . ASP A 1 360 ? -26.968 -7.105  -1.909  1.00 49.81  ? 360 ASP A OD1 1 
ATOM   2599  O OD2 . ASP A 1 360 ? -28.846 -5.980  -1.676  1.00 42.53  ? 360 ASP A OD2 1 
ATOM   2600  N N   . TYR A 1 361 ? -24.001 -3.690  -1.025  1.00 21.38  ? 361 TYR A N   1 
ATOM   2601  C CA  . TYR A 1 361 ? -23.780 -2.569  -1.937  1.00 23.70  ? 361 TYR A CA  1 
ATOM   2602  C C   . TYR A 1 361 ? -23.349 -3.031  -3.328  1.00 28.20  ? 361 TYR A C   1 
ATOM   2603  O O   . TYR A 1 361 ? -23.603 -2.343  -4.320  1.00 22.86  ? 361 TYR A O   1 
ATOM   2604  C CB  . TYR A 1 361 ? -22.740 -1.612  -1.350  1.00 24.23  ? 361 TYR A CB  1 
ATOM   2605  C CG  . TYR A 1 361 ? -21.339 -2.193  -1.403  1.00 25.42  ? 361 TYR A CG  1 
ATOM   2606  C CD1 . TYR A 1 361 ? -20.568 -2.075  -2.556  1.00 15.55  ? 361 TYR A CD1 1 
ATOM   2607  C CD2 . TYR A 1 361 ? -20.808 -2.883  -0.314  1.00 19.72  ? 361 TYR A CD2 1 
ATOM   2608  C CE1 . TYR A 1 361 ? -19.333 -2.624  -2.634  1.00 22.48  ? 361 TYR A CE1 1 
ATOM   2609  C CE2 . TYR A 1 361 ? -19.562 -3.432  -0.379  1.00 23.25  ? 361 TYR A CE2 1 
ATOM   2610  C CZ  . TYR A 1 361 ? -18.820 -3.305  -1.549  1.00 21.20  ? 361 TYR A CZ  1 
ATOM   2611  O OH  . TYR A 1 361 ? -17.571 -3.842  -1.641  1.00 19.20  ? 361 TYR A OH  1 
ATOM   2612  N N   . ALA A 1 362 ? -22.670 -4.175  -3.422  1.00 26.59  ? 362 ALA A N   1 
ATOM   2613  C CA  . ALA A 1 362 ? -22.140 -4.590  -4.715  1.00 28.77  ? 362 ALA A CA  1 
ATOM   2614  C C   . ALA A 1 362 ? -23.246 -4.950  -5.697  1.00 31.54  ? 362 ALA A C   1 
ATOM   2615  O O   . ALA A 1 362 ? -23.018 -4.901  -6.909  1.00 31.46  ? 362 ALA A O   1 
ATOM   2616  C CB  . ALA A 1 362 ? -21.174 -5.766  -4.544  1.00 29.55  ? 362 ALA A CB  1 
ATOM   2617  N N   . ARG A 1 363 ? -24.446 -5.274  -5.210  1.00 34.52  ? 363 ARG A N   1 
ATOM   2618  C CA  . ARG A 1 363 ? -25.552 -5.545  -6.123  1.00 34.46  ? 363 ARG A CA  1 
ATOM   2619  C C   . ARG A 1 363 ? -25.873 -4.330  -6.991  1.00 35.49  ? 363 ARG A C   1 
ATOM   2620  O O   . ARG A 1 363 ? -25.997 -4.449  -8.215  1.00 42.27  ? 363 ARG A O   1 
ATOM   2621  C CB  . ARG A 1 363 ? -26.783 -6.002  -5.345  1.00 38.48  ? 363 ARG A CB  1 
ATOM   2622  C CG  . ARG A 1 363 ? -26.837 -7.512  -5.172  1.00 42.45  ? 363 ARG A CG  1 
ATOM   2623  C CD  . ARG A 1 363 ? -28.184 -8.015  -4.667  1.00 43.56  ? 363 ARG A CD  1 
ATOM   2624  N NE  . ARG A 1 363 ? -28.103 -9.425  -4.299  1.00 46.70  ? 363 ARG A NE  1 
ATOM   2625  C CZ  . ARG A 1 363 ? -29.039 -10.332 -4.554  1.00 44.38  ? 363 ARG A CZ  1 
ATOM   2626  N NH1 . ARG A 1 363 ? -30.137 -10.026 -5.231  1.00 41.13  ? 363 ARG A NH1 1 
ATOM   2627  N NH2 . ARG A 1 363 ? -28.870 -11.580 -4.121  1.00 38.63  ? 363 ARG A NH2 1 
ATOM   2628  N N   . ASN A 1 364 ? -25.983 -3.141  -6.390  1.00 34.62  ? 364 ASN A N   1 
ATOM   2629  C CA  . ASN A 1 364 ? -26.446 -1.980  -7.145  1.00 34.17  ? 364 ASN A CA  1 
ATOM   2630  C C   . ASN A 1 364 ? -25.475 -0.806  -7.175  1.00 34.63  ? 364 ASN A C   1 
ATOM   2631  O O   . ASN A 1 364 ? -25.851 0.264   -7.665  1.00 31.48  ? 364 ASN A O   1 
ATOM   2632  C CB  . ASN A 1 364 ? -27.801 -1.505  -6.609  1.00 34.32  ? 364 ASN A CB  1 
ATOM   2633  C CG  . ASN A 1 364 ? -28.798 -2.625  -6.500  1.00 33.81  ? 364 ASN A CG  1 
ATOM   2634  O OD1 . ASN A 1 364 ? -29.128 -3.265  -7.497  1.00 39.33  ? 364 ASN A OD1 1 
ATOM   2635  N ND2 . ASN A 1 364 ? -29.269 -2.890  -5.293  1.00 37.45  ? 364 ASN A ND2 1 
ATOM   2636  N N   . ASN A 1 365 ? -24.247 -0.960  -6.687  1.00 32.30  ? 365 ASN A N   1 
ATOM   2637  C CA  . ASN A 1 365 ? -23.336 0.172   -6.601  1.00 27.78  ? 365 ASN A CA  1 
ATOM   2638  C C   . ASN A 1 365 ? -21.981 -0.188  -7.190  1.00 28.84  ? 365 ASN A C   1 
ATOM   2639  O O   . ASN A 1 365 ? -21.617 -1.359  -7.317  1.00 31.74  ? 365 ASN A O   1 
ATOM   2640  C CB  . ASN A 1 365 ? -23.165 0.657   -5.154  1.00 29.42  ? 365 ASN A CB  1 
ATOM   2641  C CG  . ASN A 1 365 ? -24.466 1.134   -4.538  1.00 29.27  ? 365 ASN A CG  1 
ATOM   2642  O OD1 . ASN A 1 365 ? -24.801 2.314   -4.611  1.00 22.71  ? 365 ASN A OD1 1 
ATOM   2643  N ND2 . ASN A 1 365 ? -25.207 0.213   -3.926  1.00 30.23  ? 365 ASN A ND2 1 
ATOM   2644  N N   . PHE A 1 366 ? -21.240 0.854   -7.540  1.00 29.42  ? 366 PHE A N   1 
ATOM   2645  C CA  . PHE A 1 366 ? -19.878 0.758   -8.035  1.00 28.38  ? 366 PHE A CA  1 
ATOM   2646  C C   . PHE A 1 366 ? -19.024 1.735   -7.239  1.00 27.67  ? 366 PHE A C   1 
ATOM   2647  O O   . PHE A 1 366 ? -19.511 2.779   -6.796  1.00 24.12  ? 366 PHE A O   1 
ATOM   2648  C CB  . PHE A 1 366 ? -19.801 1.090   -9.544  1.00 31.54  ? 366 PHE A CB  1 
ATOM   2649  C CG  . PHE A 1 366 ? -20.696 0.228   -10.418 1.00 30.73  ? 366 PHE A CG  1 
ATOM   2650  C CD1 . PHE A 1 366 ? -20.271 -1.016  -10.870 1.00 28.33  ? 366 PHE A CD1 1 
ATOM   2651  C CD2 . PHE A 1 366 ? -21.957 0.670   -10.786 1.00 30.51  ? 366 PHE A CD2 1 
ATOM   2652  C CE1 . PHE A 1 366 ? -21.096 -1.805  -11.669 1.00 31.85  ? 366 PHE A CE1 1 
ATOM   2653  C CE2 . PHE A 1 366 ? -22.787 -0.108  -11.588 1.00 27.62  ? 366 PHE A CE2 1 
ATOM   2654  C CZ  . PHE A 1 366 ? -22.359 -1.344  -12.031 1.00 29.76  ? 366 PHE A CZ  1 
ATOM   2655  N N   . PHE A 1 367 ? -17.753 1.395   -7.023  1.00 24.99  ? 367 PHE A N   1 
ATOM   2656  C CA  . PHE A 1 367 ? -16.844 2.391   -6.482  1.00 24.52  ? 367 PHE A CA  1 
ATOM   2657  C C   . PHE A 1 367 ? -15.543 2.383   -7.257  1.00 28.72  ? 367 PHE A C   1 
ATOM   2658  O O   . PHE A 1 367 ? -15.242 1.450   -7.989  1.00 27.29  ? 367 PHE A O   1 
ATOM   2659  C CB  . PHE A 1 367 ? -16.606 2.255   -4.951  1.00 24.43  ? 367 PHE A CB  1 
ATOM   2660  C CG  . PHE A 1 367 ? -15.909 0.982   -4.465  1.00 23.82  ? 367 PHE A CG  1 
ATOM   2661  C CD1 . PHE A 1 367 ? -14.541 0.801   -4.623  1.00 24.51  ? 367 PHE A CD1 1 
ATOM   2662  C CD2 . PHE A 1 367 ? -16.611 0.059   -3.677  1.00 24.27  ? 367 PHE A CD2 1 
ATOM   2663  C CE1 . PHE A 1 367 ? -13.885 -0.332  -4.067  1.00 24.49  ? 367 PHE A CE1 1 
ATOM   2664  C CE2 . PHE A 1 367 ? -15.980 -1.075  -3.129  1.00 23.44  ? 367 PHE A CE2 1 
ATOM   2665  C CZ  . PHE A 1 367 ? -14.600 -1.269  -3.331  1.00 24.36  ? 367 PHE A CZ  1 
ATOM   2666  N N   . SER A 1 368 ? -14.811 3.484   -7.146  1.00 27.43  ? 368 SER A N   1 
ATOM   2667  C CA  . SER A 1 368 ? -13.512 3.599   -7.779  1.00 28.10  ? 368 SER A CA  1 
ATOM   2668  C C   . SER A 1 368 ? -12.680 4.591   -6.987  1.00 30.11  ? 368 SER A C   1 
ATOM   2669  O O   . SER A 1 368 ? -13.208 5.569   -6.444  1.00 29.13  ? 368 SER A O   1 
ATOM   2670  C CB  . SER A 1 368 ? -13.637 4.036   -9.240  1.00 35.33  ? 368 SER A CB  1 
ATOM   2671  O OG  . SER A 1 368 ? -12.364 4.010   -9.863  1.00 36.59  ? 368 SER A OG  1 
ATOM   2672  N N   . SER A 1 369 ? -11.383 4.336   -6.915  1.00 30.27  ? 369 SER A N   1 
ATOM   2673  C CA  . SER A 1 369 ? -10.485 5.212   -6.191  1.00 26.37  ? 369 SER A CA  1 
ATOM   2674  C C   . SER A 1 369 ? -9.622  6.004   -7.159  1.00 32.73  ? 369 SER A C   1 
ATOM   2675  O O   . SER A 1 369 ? -9.338  5.569   -8.280  1.00 31.59  ? 369 SER A O   1 
ATOM   2676  C CB  . SER A 1 369 ? -9.587  4.438   -5.226  1.00 30.03  ? 369 SER A CB  1 
ATOM   2677  O OG  . SER A 1 369 ? -8.868  3.430   -5.903  1.00 32.14  ? 369 SER A OG  1 
ATOM   2678  N N   . ILE A 1 370 ? -9.228  7.189   -6.707  1.00 29.03  ? 370 ILE A N   1 
ATOM   2679  C CA  . ILE A 1 370 ? -8.244  8.017   -7.378  1.00 31.90  ? 370 ILE A CA  1 
ATOM   2680  C C   . ILE A 1 370 ? -7.103  8.193   -6.397  1.00 33.21  ? 370 ILE A C   1 
ATOM   2681  O O   . ILE A 1 370 ? -7.315  8.672   -5.278  1.00 33.22  ? 370 ILE A O   1 
ATOM   2682  C CB  . ILE A 1 370 ? -8.808  9.383   -7.804  1.00 34.81  ? 370 ILE A CB  1 
ATOM   2683  C CG1 . ILE A 1 370 ? -10.206 9.258   -8.399  1.00 29.15  ? 370 ILE A CG1 1 
ATOM   2684  C CG2 . ILE A 1 370 ? -7.873  10.035  -8.817  1.00 36.39  ? 370 ILE A CG2 1 
ATOM   2685  C CD1 . ILE A 1 370 ? -10.881 10.608  -8.574  1.00 32.67  ? 370 ILE A CD1 1 
ATOM   2686  N N   . LEU A 1 371 ? -5.907  7.786   -6.797  1.00 30.12  ? 371 LEU A N   1 
ATOM   2687  C CA  . LEU A 1 371 ? -4.740  7.933   -5.949  1.00 33.54  ? 371 LEU A CA  1 
ATOM   2688  C C   . LEU A 1 371 ? -3.987  9.213   -6.251  1.00 34.72  ? 371 LEU A C   1 
ATOM   2689  O O   . LEU A 1 371 ? -3.068  9.569   -5.502  1.00 32.31  ? 371 LEU A O   1 
ATOM   2690  C CB  . LEU A 1 371 ? -3.826  6.717   -6.125  1.00 28.27  ? 371 LEU A CB  1 
ATOM   2691  C CG  . LEU A 1 371 ? -4.506  5.384   -5.828  1.00 28.28  ? 371 LEU A CG  1 
ATOM   2692  C CD1 . LEU A 1 371 ? -3.562  4.242   -6.101  1.00 34.99  ? 371 LEU A CD1 1 
ATOM   2693  C CD2 . LEU A 1 371 ? -4.954  5.348   -4.370  1.00 30.23  ? 371 LEU A CD2 1 
ATOM   2694  N N   . ASN A 1 372 ? -4.483  9.963   -7.236  1.00 35.73  ? 372 ASN A N   1 
ATOM   2695  C CA  . ASN A 1 372 ? -3.742  10.820  -8.150  1.00 36.66  ? 372 ASN A CA  1 
ATOM   2696  C C   . ASN A 1 372 ? -4.047  12.306  -7.993  1.00 41.64  ? 372 ASN A C   1 
ATOM   2697  O O   . ASN A 1 372 ? -3.509  13.115  -8.750  1.00 40.60  ? 372 ASN A O   1 
ATOM   2698  C CB  . ASN A 1 372 ? -4.106  10.392  -9.578  1.00 43.45  ? 372 ASN A CB  1 
ATOM   2699  C CG  . ASN A 1 372 ? -2.960  10.474  -10.522 1.00 47.11  ? 372 ASN A CG  1 
ATOM   2700  O OD1 . ASN A 1 372 ? -1.830  10.740  -10.119 1.00 53.05  ? 372 ASN A OD1 1 
ATOM   2701  N ND2 . ASN A 1 372 ? -3.226  10.194  -11.791 1.00 43.82  ? 372 ASN A ND2 1 
ATOM   2702  N N   . VAL A 1 373 ? -4.929  12.682  -7.067  1.00 37.73  ? 373 VAL A N   1 
ATOM   2703  C CA  . VAL A 1 373 ? -5.368  14.068  -6.947  1.00 36.69  ? 373 VAL A CA  1 
ATOM   2704  C C   . VAL A 1 373 ? -4.248  14.920  -6.357  1.00 36.33  ? 373 VAL A C   1 
ATOM   2705  O O   . VAL A 1 373 ? -3.408  14.438  -5.585  1.00 38.57  ? 373 VAL A O   1 
ATOM   2706  C CB  . VAL A 1 373 ? -6.657  14.116  -6.101  1.00 33.01  ? 373 VAL A CB  1 
ATOM   2707  C CG1 . VAL A 1 373 ? -7.054  15.525  -5.702  1.00 29.64  ? 373 VAL A CG1 1 
ATOM   2708  C CG2 . VAL A 1 373 ? -7.789  13.467  -6.881  1.00 32.86  ? 373 VAL A CG2 1 
ATOM   2709  N N   . VAL A 1 374 ? -4.200  16.182  -6.759  1.00 31.55  ? 374 VAL A N   1 
ATOM   2710  C CA  . VAL A 1 374 ? -3.150  17.068  -6.237  1.00 34.90  ? 374 VAL A CA  1 
ATOM   2711  C C   . VAL A 1 374 ? -3.344  17.244  -4.735  1.00 35.59  ? 374 VAL A C   1 
ATOM   2712  O O   . VAL A 1 374 ? -4.454  17.579  -4.285  1.00 38.77  ? 374 VAL A O   1 
ATOM   2713  C CB  . VAL A 1 374 ? -3.170  18.415  -6.961  1.00 38.66  ? 374 VAL A CB  1 
ATOM   2714  C CG1 . VAL A 1 374 ? -2.143  19.374  -6.344  1.00 38.55  ? 374 VAL A CG1 1 
ATOM   2715  C CG2 . VAL A 1 374 ? -2.862  18.209  -8.434  1.00 39.42  ? 374 VAL A CG2 1 
ATOM   2716  N N   . PRO A 1 375 ? -2.324  16.996  -3.922  1.00 36.70  ? 375 PRO A N   1 
ATOM   2717  C CA  . PRO A 1 375 ? -2.491  17.144  -2.476  1.00 31.27  ? 375 PRO A CA  1 
ATOM   2718  C C   . PRO A 1 375 ? -2.928  18.554  -2.119  1.00 32.30  ? 375 PRO A C   1 
ATOM   2719  O O   . PRO A 1 375 ? -2.417  19.540  -2.656  1.00 33.72  ? 375 PRO A O   1 
ATOM   2720  C CB  . PRO A 1 375 ? -1.096  16.833  -1.920  1.00 32.81  ? 375 PRO A CB  1 
ATOM   2721  C CG  . PRO A 1 375 ? -0.434  16.011  -2.992  1.00 33.75  ? 375 PRO A CG  1 
ATOM   2722  C CD  . PRO A 1 375 ? -0.972  16.540  -4.287  1.00 30.99  ? 375 PRO A CD  1 
ATOM   2723  N N   . ALA A 1 376 ? -3.900  18.631  -1.218  1.00 27.79  ? 376 ALA A N   1 
ATOM   2724  C CA  . ALA A 1 376 ? -4.277  19.885  -0.584  1.00 30.93  ? 376 ALA A CA  1 
ATOM   2725  C C   . ALA A 1 376 ? -4.777  19.549  0.811   1.00 26.56  ? 376 ALA A C   1 
ATOM   2726  O O   . ALA A 1 376 ? -5.070  18.393  1.112   1.00 24.69  ? 376 ALA A O   1 
ATOM   2727  C CB  . ALA A 1 376 ? -5.341  20.635  -1.401  1.00 28.17  ? 376 ALA A CB  1 
ATOM   2728  N N   . GLY A 1 377 ? -4.833  20.555  1.679   1.00 27.01  ? 377 GLY A N   1 
ATOM   2729  C CA  . GLY A 1 377 ? -5.469  20.360  2.967   1.00 29.02  ? 377 GLY A CA  1 
ATOM   2730  C C   . GLY A 1 377 ? -6.913  19.906  2.825   1.00 30.87  ? 377 GLY A C   1 
ATOM   2731  O O   . GLY A 1 377 ? -7.557  20.086  1.791   1.00 29.64  ? 377 GLY A O   1 
ATOM   2732  N N   . LEU A 1 378 ? -7.419  19.297  3.899   1.00 33.48  ? 378 LEU A N   1 
ATOM   2733  C CA  . LEU A 1 378 ? -8.754  18.698  3.880   1.00 29.79  ? 378 LEU A CA  1 
ATOM   2734  C C   . LEU A 1 378 ? -9.849  19.721  3.565   1.00 25.93  ? 378 LEU A C   1 
ATOM   2735  O O   . LEU A 1 378 ? -10.823 19.401  2.877   1.00 28.51  ? 378 LEU A O   1 
ATOM   2736  C CB  . LEU A 1 378 ? -9.029  18.014  5.220   1.00 29.39  ? 378 LEU A CB  1 
ATOM   2737  C CG  . LEU A 1 378 ? -10.446 17.441  5.344   1.00 25.41  ? 378 LEU A CG  1 
ATOM   2738  C CD1 . LEU A 1 378 ? -10.709 16.391  4.260   1.00 23.67  ? 378 LEU A CD1 1 
ATOM   2739  C CD2 . LEU A 1 378 ? -10.691 16.882  6.717   1.00 26.57  ? 378 LEU A CD2 1 
ATOM   2740  N N   . ALA A 1 379 ? -9.717  20.949  4.060   1.00 26.10  ? 379 ALA A N   1 
ATOM   2741  C CA  . ALA A 1 379 ? -10.711 21.971  3.748   1.00 28.16  ? 379 ALA A CA  1 
ATOM   2742  C C   . ALA A 1 379 ? -10.780 22.250  2.248   1.00 31.36  ? 379 ALA A C   1 
ATOM   2743  O O   . ALA A 1 379 ? -11.866 22.425  1.681   1.00 30.25  ? 379 ALA A O   1 
ATOM   2744  C CB  . ALA A 1 379 ? -10.394 23.250  4.514   1.00 29.53  ? 379 ALA A CB  1 
ATOM   2745  N N   . ASP A 1 380 ? -9.635  22.273  1.581   1.00 30.38  ? 380 ASP A N   1 
ATOM   2746  C CA  . ASP A 1 380 ? -9.639  22.594  0.161   1.00 32.23  ? 380 ASP A CA  1 
ATOM   2747  C C   . ASP A 1 380 ? -10.094 21.403  -0.681  1.00 31.24  ? 380 ASP A C   1 
ATOM   2748  O O   . ASP A 1 380 ? -10.825 21.576  -1.667  1.00 33.78  ? 380 ASP A O   1 
ATOM   2749  C CB  . ASP A 1 380 ? -8.248  23.078  -0.245  1.00 33.57  ? 380 ASP A CB  1 
ATOM   2750  C CG  . ASP A 1 380 ? -7.816  24.303  0.541   1.00 42.56  ? 380 ASP A CG  1 
ATOM   2751  O OD1 . ASP A 1 380 ? -8.679  25.182  0.747   1.00 39.34  ? 380 ASP A OD1 1 
ATOM   2752  O OD2 . ASP A 1 380 ? -6.624  24.412  0.929   1.00 46.79  ? 380 ASP A OD2 1 
ATOM   2753  N N   . LEU A 1 381 ? -9.688  20.187  -0.303  1.00 27.83  ? 381 LEU A N   1 
ATOM   2754  C CA  . LEU A 1 381 ? -10.181 18.993  -0.985  1.00 30.89  ? 381 LEU A CA  1 
ATOM   2755  C C   . LEU A 1 381 ? -11.703 18.950  -0.989  1.00 31.20  ? 381 LEU A C   1 
ATOM   2756  O O   . LEU A 1 381 ? -12.334 18.767  -2.041  1.00 29.11  ? 381 LEU A O   1 
ATOM   2757  C CB  . LEU A 1 381 ? -9.636  17.726  -0.311  1.00 25.80  ? 381 LEU A CB  1 
ATOM   2758  C CG  . LEU A 1 381 ? -8.219  17.229  -0.593  1.00 32.10  ? 381 LEU A CG  1 
ATOM   2759  C CD1 . LEU A 1 381 ? -8.030  15.859  0.018   1.00 28.78  ? 381 LEU A CD1 1 
ATOM   2760  C CD2 . LEU A 1 381 ? -7.940  17.174  -2.099  1.00 30.58  ? 381 LEU A CD2 1 
ATOM   2761  N N   . LEU A 1 382 ? -12.317 19.080  0.194   1.00 25.75  ? 382 LEU A N   1 
ATOM   2762  C CA  . LEU A 1 382 ? -13.774 18.998  0.242   1.00 27.32  ? 382 LEU A CA  1 
ATOM   2763  C C   . LEU A 1 382 ? -14.398 20.138  -0.539  1.00 26.30  ? 382 LEU A C   1 
ATOM   2764  O O   . LEU A 1 382 ? -15.454 19.965  -1.153  1.00 29.32  ? 382 LEU A O   1 
ATOM   2765  C CB  . LEU A 1 382 ? -14.277 19.013  1.681   1.00 23.95  ? 382 LEU A CB  1 
ATOM   2766  C CG  . LEU A 1 382 ? -13.736 17.937  2.607   1.00 23.35  ? 382 LEU A CG  1 
ATOM   2767  C CD1 . LEU A 1 382 ? -14.253 18.209  3.993   1.00 26.52  ? 382 LEU A CD1 1 
ATOM   2768  C CD2 . LEU A 1 382 ? -14.129 16.547  2.132   1.00 19.66  ? 382 LEU A CD2 1 
ATOM   2769  N N   . ARG A 1 383 ? -13.746 21.296  -0.560  1.00 23.75  ? 383 ARG A N   1 
ATOM   2770  C CA  . ARG A 1 383 ? -14.302 22.417  -1.313  1.00 30.90  ? 383 ARG A CA  1 
ATOM   2771  C C   . ARG A 1 383 ? -14.369 22.085  -2.803  1.00 30.52  ? 383 ARG A C   1 
ATOM   2772  O O   . ARG A 1 383 ? -15.374 22.382  -3.470  1.00 27.28  ? 383 ARG A O   1 
ATOM   2773  C CB  . ARG A 1 383 ? -13.478 23.688  -1.052  1.00 27.93  ? 383 ARG A CB  1 
ATOM   2774  C CG  . ARG A 1 383 ? -14.023 24.946  -1.715  1.00 29.83  ? 383 ARG A CG  1 
ATOM   2775  C CD  . ARG A 1 383 ? -15.004 25.747  -0.814  1.00 32.79  ? 383 ARG A CD  1 
ATOM   2776  N NE  . ARG A 1 383 ? -16.397 25.287  -0.883  1.00 31.52  ? 383 ARG A NE  1 
ATOM   2777  C CZ  . ARG A 1 383 ? -17.179 25.340  -1.956  1.00 32.45  ? 383 ARG A CZ  1 
ATOM   2778  N NH1 . ARG A 1 383 ? -16.748 25.827  -3.109  1.00 31.58  ? 383 ARG A NH1 1 
ATOM   2779  N NH2 . ARG A 1 383 ? -18.429 24.892  -1.868  1.00 29.49  ? 383 ARG A NH2 1 
ATOM   2780  N N   . SER A 1 384 ? -13.339 21.398  -3.321  1.00 28.19  ? 384 SER A N   1 
ATOM   2781  C CA  . SER A 1 384 ? -13.291 21.043  -4.738  1.00 27.62  ? 384 SER A CA  1 
ATOM   2782  C C   . SER A 1 384 ? -14.295 19.951  -5.088  1.00 28.62  ? 384 SER A C   1 
ATOM   2783  O O   . SER A 1 384 ? -14.822 19.929  -6.209  1.00 31.86  ? 384 SER A O   1 
ATOM   2784  C CB  . SER A 1 384 ? -11.876 20.598  -5.112  1.00 34.11  ? 384 SER A CB  1 
ATOM   2785  O OG  . SER A 1 384 ? -10.928 21.591  -4.744  1.00 35.58  ? 384 SER A OG  1 
ATOM   2786  N N   . LEU A 1 385 ? -14.558 19.024  -4.163  1.00 27.87  ? 385 LEU A N   1 
ATOM   2787  C CA  . LEU A 1 385 ? -15.615 18.042  -4.391  1.00 27.16  ? 385 LEU A CA  1 
ATOM   2788  C C   . LEU A 1 385 ? -16.979 18.724  -4.450  1.00 28.80  ? 385 LEU A C   1 
ATOM   2789  O O   . LEU A 1 385 ? -17.849 18.336  -5.246  1.00 25.95  ? 385 LEU A O   1 
ATOM   2790  C CB  . LEU A 1 385 ? -15.613 16.994  -3.280  1.00 25.88  ? 385 LEU A CB  1 
ATOM   2791  C CG  . LEU A 1 385 ? -14.377 16.163  -2.965  1.00 29.92  ? 385 LEU A CG  1 
ATOM   2792  C CD1 . LEU A 1 385 ? -14.770 14.947  -2.151  1.00 26.87  ? 385 LEU A CD1 1 
ATOM   2793  C CD2 . LEU A 1 385 ? -13.665 15.749  -4.210  1.00 27.17  ? 385 LEU A CD2 1 
ATOM   2794  N N   . GLU A 1 386 ? -17.190 19.719  -3.583  1.00 22.50  ? 386 GLU A N   1 
ATOM   2795  C CA  . GLU A 1 386 ? -18.416 20.513  -3.621  1.00 27.17  ? 386 GLU A CA  1 
ATOM   2796  C C   . GLU A 1 386 ? -18.449 21.420  -4.843  1.00 31.67  ? 386 GLU A C   1 
ATOM   2797  O O   . GLU A 1 386 ? -19.482 21.520  -5.508  1.00 31.27  ? 386 GLU A O   1 
ATOM   2798  C CB  . GLU A 1 386 ? -18.551 21.352  -2.365  1.00 25.99  ? 386 GLU A CB  1 
ATOM   2799  C CG  . GLU A 1 386 ? -18.889 20.597  -1.117  1.00 29.85  ? 386 GLU A CG  1 
ATOM   2800  C CD  . GLU A 1 386 ? -18.921 21.526  0.077   1.00 33.62  ? 386 GLU A CD  1 
ATOM   2801  O OE1 . GLU A 1 386 ? -19.473 22.639  -0.086  1.00 36.64  ? 386 GLU A OE1 1 
ATOM   2802  O OE2 . GLU A 1 386 ? -18.408 21.165  1.161   1.00 31.54  ? 386 GLU A OE2 1 
ATOM   2803  N N   . ARG A 1 387 ? -17.328 22.081  -5.162  1.00 29.11  ? 387 ARG A N   1 
ATOM   2804  C CA  . ARG A 1 387 ? -17.282 22.870  -6.391  1.00 35.06  ? 387 ARG A CA  1 
ATOM   2805  C C   . ARG A 1 387 ? -17.608 22.002  -7.604  1.00 32.34  ? 387 ARG A C   1 
ATOM   2806  O O   . ARG A 1 387 ? -18.253 22.457  -8.557  1.00 35.86  ? 387 ARG A O   1 
ATOM   2807  C CB  . ARG A 1 387 ? -15.910 23.545  -6.537  1.00 32.79  ? 387 ARG A CB  1 
ATOM   2808  C CG  . ARG A 1 387 ? -15.777 24.503  -7.730  1.00 35.92  ? 387 ARG A CG  1 
ATOM   2809  C CD  . ARG A 1 387 ? -14.323 24.977  -7.958  1.00 38.93  ? 387 ARG A CD  1 
ATOM   2810  N NE  . ARG A 1 387 ? -13.639 25.093  -6.679  1.00 43.21  ? 387 ARG A NE  1 
ATOM   2811  C CZ  . ARG A 1 387 ? -12.470 24.545  -6.387  1.00 37.48  ? 387 ARG A CZ  1 
ATOM   2812  N NH1 . ARG A 1 387 ? -11.722 23.974  -7.314  1.00 38.08  ? 387 ARG A NH1 1 
ATOM   2813  N NH2 . ARG A 1 387 ? -12.052 24.552  -5.126  1.00 39.37  ? 387 ARG A NH2 1 
ATOM   2814  N N   . ALA A 1 388 ? -17.198 20.740  -7.572  1.00 31.63  ? 388 ALA A N   1 
ATOM   2815  C CA  . ALA A 1 388 ? -17.506 19.811  -8.650  1.00 32.36  ? 388 ALA A CA  1 
ATOM   2816  C C   . ALA A 1 388 ? -18.909 19.234  -8.548  1.00 30.33  ? 388 ALA A C   1 
ATOM   2817  O O   . ALA A 1 388 ? -19.368 18.610  -9.506  1.00 37.91  ? 388 ALA A O   1 
ATOM   2818  C CB  . ALA A 1 388 ? -16.484 18.667  -8.662  1.00 31.01  ? 388 ALA A CB  1 
ATOM   2819  N N   . GLY A 1 389 ? -19.596 19.414  -7.421  1.00 24.18  ? 389 GLY A N   1 
ATOM   2820  C CA  . GLY A 1 389 ? -20.905 18.812  -7.251  1.00 29.58  ? 389 GLY A CA  1 
ATOM   2821  C C   . GLY A 1 389 ? -20.892 17.332  -6.940  1.00 31.75  ? 389 GLY A C   1 
ATOM   2822  O O   . GLY A 1 389 ? -21.908 16.661  -7.123  1.00 27.01  ? 389 GLY A O   1 
ATOM   2823  N N   . VAL A 1 390 ? -19.772 16.783  -6.471  1.00 32.01  ? 390 VAL A N   1 
ATOM   2824  C CA  . VAL A 1 390 ? -19.721 15.339  -6.292  1.00 28.94  ? 390 VAL A CA  1 
ATOM   2825  C C   . VAL A 1 390 ? -19.253 14.961  -4.894  1.00 29.75  ? 390 VAL A C   1 
ATOM   2826  O O   . VAL A 1 390 ? -18.809 13.830  -4.680  1.00 30.19  ? 390 VAL A O   1 
ATOM   2827  C CB  . VAL A 1 390 ? -18.830 14.704  -7.367  1.00 25.04  ? 390 VAL A CB  1 
ATOM   2828  C CG1 . VAL A 1 390 ? -19.352 15.088  -8.746  1.00 32.54  ? 390 VAL A CG1 1 
ATOM   2829  C CG2 . VAL A 1 390 ? -17.391 15.164  -7.209  1.00 25.07  ? 390 VAL A CG2 1 
ATOM   2830  N N   . ARG A 1 391 ? -19.353 15.882  -3.932  1.00 24.70  ? 391 ARG A N   1 
ATOM   2831  C CA  . ARG A 1 391 ? -19.047 15.514  -2.554  1.00 28.52  ? 391 ARG A CA  1 
ATOM   2832  C C   . ARG A 1 391 ? -20.082 14.515  -2.041  1.00 28.12  ? 391 ARG A C   1 
ATOM   2833  O O   . ARG A 1 391 ? -21.283 14.686  -2.259  1.00 29.39  ? 391 ARG A O   1 
ATOM   2834  C CB  . ARG A 1 391 ? -19.015 16.748  -1.649  1.00 28.29  ? 391 ARG A CB  1 
ATOM   2835  C CG  . ARG A 1 391 ? -18.934 16.376  -0.164  1.00 30.47  ? 391 ARG A CG  1 
ATOM   2836  C CD  . ARG A 1 391 ? -18.560 17.542  0.719   1.00 26.65  ? 391 ARG A CD  1 
ATOM   2837  N NE  . ARG A 1 391 ? -18.579 17.141  2.118   1.00 24.56  ? 391 ARG A NE  1 
ATOM   2838  C CZ  . ARG A 1 391 ? -18.237 17.924  3.132   1.00 26.57  ? 391 ARG A CZ  1 
ATOM   2839  N NH1 . ARG A 1 391 ? -17.874 19.179  2.942   1.00 26.57  ? 391 ARG A NH1 1 
ATOM   2840  N NH2 . ARG A 1 391 ? -18.258 17.432  4.370   1.00 25.58  ? 391 ARG A NH2 1 
ATOM   2841  N N   . TYR A 1 392 ? -19.616 13.471  -1.349  1.00 29.82  ? 392 TYR A N   1 
ATOM   2842  C CA  . TYR A 1 392 ? -20.505 12.379  -0.950  1.00 24.99  ? 392 TYR A CA  1 
ATOM   2843  C C   . TYR A 1 392 ? -21.734 12.888  -0.205  1.00 25.13  ? 392 TYR A C   1 
ATOM   2844  O O   . TYR A 1 392 ? -21.621 13.597  0.799   1.00 22.36  ? 392 TYR A O   1 
ATOM   2845  C CB  . TYR A 1 392 ? -19.793 11.363  -0.066  1.00 18.92  ? 392 TYR A CB  1 
ATOM   2846  C CG  . TYR A 1 392 ? -20.732 10.228  0.262   1.00 22.81  ? 392 TYR A CG  1 
ATOM   2847  C CD1 . TYR A 1 392 ? -21.014 9.259   -0.687  1.00 25.25  ? 392 TYR A CD1 1 
ATOM   2848  C CD2 . TYR A 1 392 ? -21.413 10.167  1.478   1.00 24.94  ? 392 TYR A CD2 1 
ATOM   2849  C CE1 . TYR A 1 392 ? -21.903 8.250   -0.429  1.00 26.85  ? 392 TYR A CE1 1 
ATOM   2850  C CE2 . TYR A 1 392 ? -22.312 9.150   1.745   1.00 20.05  ? 392 TYR A CE2 1 
ATOM   2851  C CZ  . TYR A 1 392 ? -22.544 8.192   0.778   1.00 25.70  ? 392 TYR A CZ  1 
ATOM   2852  O OH  . TYR A 1 392 ? -23.404 7.151   0.996   1.00 24.98  ? 392 TYR A OH  1 
ATOM   2853  N N   . ASP A 1 393 ? -22.898 12.426  -0.658  1.00 27.34  ? 393 ASP A N   1 
ATOM   2854  C CA  . ASP A 1 393 ? -24.216 12.879  -0.217  1.00 28.48  ? 393 ASP A CA  1 
ATOM   2855  C C   . ASP A 1 393 ? -24.952 11.674  0.345   1.00 26.59  ? 393 ASP A C   1 
ATOM   2856  O O   . ASP A 1 393 ? -25.311 10.762  -0.407  1.00 25.94  ? 393 ASP A O   1 
ATOM   2857  C CB  . ASP A 1 393 ? -24.991 13.494  -1.388  1.00 28.01  ? 393 ASP A CB  1 
ATOM   2858  C CG  . ASP A 1 393 ? -26.387 13.993  -0.996  1.00 34.94  ? 393 ASP A CG  1 
ATOM   2859  O OD1 . ASP A 1 393 ? -27.086 13.321  -0.220  1.00 38.02  ? 393 ASP A OD1 1 
ATOM   2860  O OD2 . ASP A 1 393 ? -26.802 15.068  -1.476  1.00 38.95  ? 393 ASP A OD2 1 
ATOM   2861  N N   . LYS A 1 394 ? -25.220 11.688  1.652   1.00 27.62  ? 394 LYS A N   1 
ATOM   2862  C CA  . LYS A 1 394 ? -25.853 10.526  2.274   1.00 33.43  ? 394 LYS A CA  1 
ATOM   2863  C C   . LYS A 1 394 ? -27.219 10.215  1.660   1.00 32.14  ? 394 LYS A C   1 
ATOM   2864  O O   . LYS A 1 394 ? -27.596 9.044   1.556   1.00 34.11  ? 394 LYS A O   1 
ATOM   2865  C CB  . LYS A 1 394 ? -25.975 10.734  3.788   1.00 35.50  ? 394 LYS A CB  1 
ATOM   2866  C CG  . LYS A 1 394 ? -26.402 12.133  4.198   1.00 41.32  ? 394 LYS A CG  1 
ATOM   2867  C CD  . LYS A 1 394 ? -26.301 12.369  5.703   1.00 37.64  ? 394 LYS A CD  1 
ATOM   2868  C CE  . LYS A 1 394 ? -27.421 13.288  6.180   1.00 40.55  ? 394 LYS A CE  1 
ATOM   2869  N NZ  . LYS A 1 394 ? -27.167 14.712  5.794   1.00 44.23  ? 394 LYS A NZ  1 
ATOM   2870  N N   . ASP A 1 395 ? -27.955 11.234  1.204   1.00 31.00  ? 395 ASP A N   1 
ATOM   2871  C CA  . ASP A 1 395 ? -29.321 11.001  0.726   1.00 39.85  ? 395 ASP A CA  1 
ATOM   2872  C C   . ASP A 1 395 ? -29.354 10.265  -0.615  1.00 34.91  ? 395 ASP A C   1 
ATOM   2873  O O   . ASP A 1 395 ? -30.310 9.530   -0.892  1.00 32.19  ? 395 ASP A O   1 
ATOM   2874  C CB  . ASP A 1 395 ? -30.078 12.329  0.613   1.00 35.92  ? 395 ASP A CB  1 
ATOM   2875  C CG  . ASP A 1 395 ? -30.097 13.103  1.914   1.00 41.46  ? 395 ASP A CG  1 
ATOM   2876  O OD1 . ASP A 1 395 ? -30.506 12.531  2.952   1.00 41.68  ? 395 ASP A OD1 1 
ATOM   2877  O OD2 . ASP A 1 395 ? -29.726 14.296  1.891   1.00 41.77  ? 395 ASP A OD2 1 
ATOM   2878  N N   . SER A 1 396 ? -28.351 10.464  -1.468  1.00 28.24  ? 396 SER A N   1 
ATOM   2879  C CA  . SER A 1 396 ? -28.272 9.705   -2.709  1.00 32.68  ? 396 SER A CA  1 
ATOM   2880  C C   . SER A 1 396 ? -27.367 8.482   -2.609  1.00 30.16  ? 396 SER A C   1 
ATOM   2881  O O   . SER A 1 396 ? -27.500 7.562   -3.422  1.00 36.85  ? 396 SER A O   1 
ATOM   2882  C CB  . SER A 1 396 ? -27.767 10.598  -3.851  1.00 31.64  ? 396 SER A CB  1 
ATOM   2883  O OG  . SER A 1 396 ? -26.507 11.146  -3.519  1.00 32.20  ? 396 SER A OG  1 
ATOM   2884  N N   . GLY A 1 397 ? -26.456 8.454   -1.646  1.00 28.15  ? 397 GLY A N   1 
ATOM   2885  C CA  . GLY A 1 397 ? -25.446 7.421   -1.608  1.00 31.68  ? 397 GLY A CA  1 
ATOM   2886  C C   . GLY A 1 397 ? -24.386 7.560   -2.675  1.00 31.34  ? 397 GLY A C   1 
ATOM   2887  O O   . GLY A 1 397 ? -23.680 6.595   -2.951  1.00 34.70  ? 397 GLY A O   1 
ATOM   2888  N N   . GLU A 1 398 ? -24.255 8.740   -3.281  1.00 29.42  ? 398 GLU A N   1 
ATOM   2889  C CA  . GLU A 1 398 ? -23.359 8.978   -4.399  1.00 31.00  ? 398 GLU A CA  1 
ATOM   2890  C C   . GLU A 1 398 ? -22.407 10.130  -4.098  1.00 30.47  ? 398 GLU A C   1 
ATOM   2891  O O   . GLU A 1 398 ? -22.711 11.023  -3.299  1.00 30.23  ? 398 GLU A O   1 
ATOM   2892  C CB  . GLU A 1 398 ? -24.150 9.287   -5.678  1.00 32.85  ? 398 GLU A CB  1 
ATOM   2893  C CG  . GLU A 1 398 ? -25.169 8.214   -6.042  1.00 33.71  ? 398 GLU A CG  1 
ATOM   2894  C CD  . GLU A 1 398 ? -25.181 7.905   -7.529  1.00 34.45  ? 398 GLU A CD  1 
ATOM   2895  O OE1 . GLU A 1 398 ? -24.490 8.607   -8.293  1.00 37.33  ? 398 GLU A OE1 1 
ATOM   2896  O OE2 . GLU A 1 398 ? -25.885 6.961   -7.937  1.00 35.98  ? 398 GLU A OE2 1 
ATOM   2897  N N   . GLY A 1 399 ? -21.259 10.100  -4.768  1.00 24.20  ? 399 GLY A N   1 
ATOM   2898  C CA  . GLY A 1 399 ? -20.195 11.058  -4.599  1.00 21.50  ? 399 GLY A CA  1 
ATOM   2899  C C   . GLY A 1 399 ? -18.950 10.452  -3.971  1.00 27.63  ? 399 GLY A C   1 
ATOM   2900  O O   . GLY A 1 399 ? -18.769 9.226   -3.900  1.00 26.06  ? 399 GLY A O   1 
ATOM   2901  N N   . ALA A 1 400 ? -18.091 11.339  -3.469  1.00 26.79  ? 400 ALA A N   1 
ATOM   2902  C CA  . ALA A 1 400 ? -16.720 10.991  -3.130  1.00 26.12  ? 400 ALA A CA  1 
ATOM   2903  C C   . ALA A 1 400 ? -16.395 11.346  -1.684  1.00 25.41  ? 400 ALA A C   1 
ATOM   2904  O O   . ALA A 1 400 ? -16.891 12.341  -1.148  1.00 27.32  ? 400 ALA A O   1 
ATOM   2905  C CB  . ALA A 1 400 ? -15.754 11.713  -4.050  1.00 25.74  ? 400 ALA A CB  1 
ATOM   2906  N N   . VAL A 1 401 ? -15.520 10.539  -1.075  1.00 23.23  ? 401 VAL A N   1 
ATOM   2907  C CA  . VAL A 1 401 ? -14.983 10.795  0.258   1.00 22.46  ? 401 VAL A CA  1 
ATOM   2908  C C   . VAL A 1 401 ? -13.452 10.806  0.201   1.00 24.47  ? 401 VAL A C   1 
ATOM   2909  O O   . VAL A 1 401 ? -12.840 10.242  -0.705  1.00 23.17  ? 401 VAL A O   1 
ATOM   2910  C CB  . VAL A 1 401 ? -15.479 9.753   1.263   1.00 22.33  ? 401 VAL A CB  1 
ATOM   2911  C CG1 . VAL A 1 401 ? -16.996 9.802   1.400   1.00 18.16  ? 401 VAL A CG1 1 
ATOM   2912  C CG2 . VAL A 1 401 ? -15.073 8.398   0.788   1.00 26.10  ? 401 VAL A CG2 1 
ATOM   2913  N N   . VAL A 1 402 ? -12.832 11.458  1.201   1.00 22.13  ? 402 VAL A N   1 
ATOM   2914  C CA  . VAL A 1 402 ? -11.378 11.596  1.272   1.00 23.95  ? 402 VAL A CA  1 
ATOM   2915  C C   . VAL A 1 402 ? -10.789 10.483  2.136   1.00 28.24  ? 402 VAL A C   1 
ATOM   2916  O O   . VAL A 1 402 ? -11.192 10.290  3.295   1.00 25.35  ? 402 VAL A O   1 
ATOM   2917  C CB  . VAL A 1 402 ? -10.977 12.978  1.824   1.00 21.92  ? 402 VAL A CB  1 
ATOM   2918  C CG1 . VAL A 1 402 ? -9.481  13.080  1.957   1.00 24.65  ? 402 VAL A CG1 1 
ATOM   2919  C CG2 . VAL A 1 402 ? -11.486 14.075  0.932   1.00 26.81  ? 402 VAL A CG2 1 
ATOM   2920  N N   . LEU A 1 403 ? -9.807  9.764   1.583   1.00 25.25  ? 403 LEU A N   1 
ATOM   2921  C CA  . LEU A 1 403 ? -9.030  8.805   2.363   1.00 23.69  ? 403 LEU A CA  1 
ATOM   2922  C C   . LEU A 1 403 ? -7.645  9.315   2.743   1.00 24.28  ? 403 LEU A C   1 
ATOM   2923  O O   . LEU A 1 403 ? -7.068  8.823   3.717   1.00 22.81  ? 403 LEU A O   1 
ATOM   2924  C CB  . LEU A 1 403 ? -8.897  7.486   1.600   1.00 21.05  ? 403 LEU A CB  1 
ATOM   2925  C CG  . LEU A 1 403 ? -10.214 7.010   0.969   1.00 29.97  ? 403 LEU A CG  1 
ATOM   2926  C CD1 . LEU A 1 403 ? -9.959  5.954   -0.063  1.00 34.36  ? 403 LEU A CD1 1 
ATOM   2927  C CD2 . LEU A 1 403 ? -11.239 6.522   1.962   1.00 25.92  ? 403 LEU A CD2 1 
ATOM   2928  N N   . GLY A 1 404 ? -7.119  10.304  2.027   1.00 28.97  ? 404 GLY A N   1 
ATOM   2929  C CA  . GLY A 1 404 ? -5.843  10.921  2.345   1.00 30.71  ? 404 GLY A CA  1 
ATOM   2930  C C   . GLY A 1 404 ? -5.672  12.248  1.629   1.00 30.25  ? 404 GLY A C   1 
ATOM   2931  O O   . GLY A 1 404 ? -6.006  12.368  0.447   1.00 29.95  ? 404 GLY A O   1 
ATOM   2932  N N   . CYS A 1 405 ? -5.196  13.265  2.347   1.00 27.72  ? 405 CYS A N   1 
ATOM   2933  C CA  . CYS A 1 405 ? -4.948  14.568  1.750   1.00 30.13  ? 405 CYS A CA  1 
ATOM   2934  C C   . CYS A 1 405 ? -3.595  14.639  1.076   1.00 34.41  ? 405 CYS A C   1 
ATOM   2935  O O   . CYS A 1 405 ? -3.385  15.505  0.219   1.00 29.24  ? 405 CYS A O   1 
ATOM   2936  C CB  . CYS A 1 405 ? -5.002  15.663  2.816   1.00 34.19  ? 405 CYS A CB  1 
ATOM   2937  S SG  . CYS A 1 405 ? -6.629  15.877  3.554   1.00 38.81  ? 405 CYS A SG  1 
ATOM   2938  N N   . ASN A 1 406 ? -2.670  13.765  1.462   1.00 30.07  ? 406 ASN A N   1 
ATOM   2939  C CA  . ASN A 1 406 ? -1.306  13.858  0.970   1.00 34.79  ? 406 ASN A CA  1 
ATOM   2940  C C   . ASN A 1 406 ? -0.577  12.535  1.179   1.00 33.70  ? 406 ASN A C   1 
ATOM   2941  O O   . ASN A 1 406 ? 0.301   12.442  2.041   1.00 33.22  ? 406 ASN A O   1 
ATOM   2942  C CB  . ASN A 1 406 ? -0.574  14.989  1.679   1.00 30.81  ? 406 ASN A CB  1 
ATOM   2943  C CG  . ASN A 1 406 ? 0.818   15.195  1.132   1.00 38.63  ? 406 ASN A CG  1 
ATOM   2944  O OD1 . ASN A 1 406 ? 1.039   15.045  -0.068  1.00 33.41  ? 406 ASN A OD1 1 
ATOM   2945  N ND2 . ASN A 1 406 ? 1.767   15.514  2.006   1.00 36.51  ? 406 ASN A ND2 1 
ATOM   2946  N N   . SER A 1 407 ? -0.957  11.509  0.416   1.00 31.34  ? 407 SER A N   1 
ATOM   2947  C CA  . SER A 1 407 ? -0.498  10.142  0.619   1.00 35.74  ? 407 SER A CA  1 
ATOM   2948  C C   . SER A 1 407 ? 0.540   9.733   -0.421  1.00 35.02  ? 407 SER A C   1 
ATOM   2949  O O   . SER A 1 407 ? 0.606   10.284  -1.524  1.00 34.82  ? 407 SER A O   1 
ATOM   2950  C CB  . SER A 1 407 ? -1.679  9.161   0.569   1.00 33.00  ? 407 SER A CB  1 
ATOM   2951  O OG  . SER A 1 407 ? -1.257  7.852   0.168   1.00 36.80  ? 407 SER A OG  1 
ATOM   2952  N N   . ASP A 1 408 ? 1.330   8.721   -0.064  1.00 33.39  ? 408 ASP A N   1 
ATOM   2953  C CA  . ASP A 1 408 ? 2.313   8.157   -0.976  1.00 37.19  ? 408 ASP A CA  1 
ATOM   2954  C C   . ASP A 1 408 ? 1.750   7.078   -1.884  1.00 35.17  ? 408 ASP A C   1 
ATOM   2955  O O   . ASP A 1 408 ? 2.457   6.632   -2.793  1.00 33.97  ? 408 ASP A O   1 
ATOM   2956  C CB  . ASP A 1 408 ? 3.482   7.588   -0.194  1.00 32.75  ? 408 ASP A CB  1 
ATOM   2957  C CG  . ASP A 1 408 ? 4.409   8.654   0.288   1.00 41.27  ? 408 ASP A CG  1 
ATOM   2958  O OD1 . ASP A 1 408 ? 5.029   9.326   -0.568  1.00 53.80  ? 408 ASP A OD1 1 
ATOM   2959  O OD2 . ASP A 1 408 ? 4.519   8.832   1.516   1.00 44.86  ? 408 ASP A OD2 1 
ATOM   2960  N N   . LEU A 1 409 ? 0.497   6.672   -1.668  1.00 36.42  ? 409 LEU A N   1 
ATOM   2961  C CA  . LEU A 1 409 ? -0.084  5.558   -2.404  1.00 30.64  ? 409 LEU A CA  1 
ATOM   2962  C C   . LEU A 1 409 ? 0.104   5.715   -3.903  1.00 36.57  ? 409 LEU A C   1 
ATOM   2963  O O   . LEU A 1 409 ? 0.570   4.796   -4.587  1.00 33.96  ? 409 LEU A O   1 
ATOM   2964  C CB  . LEU A 1 409 ? -1.563  5.439   -2.068  1.00 32.16  ? 409 LEU A CB  1 
ATOM   2965  C CG  . LEU A 1 409 ? -1.826  4.546   -0.863  1.00 33.54  ? 409 LEU A CG  1 
ATOM   2966  C CD1 . LEU A 1 409 ? -3.262  4.099   -0.875  1.00 27.19  ? 409 LEU A CD1 1 
ATOM   2967  C CD2 . LEU A 1 409 ? -0.876  3.356   -0.899  1.00 35.08  ? 409 LEU A CD2 1 
ATOM   2968  N N   . GLY A 1 410 ? -0.282  6.861   -4.438  1.00 37.04  ? 410 GLY A N   1 
ATOM   2969  C CA  . GLY A 1 410 ? -0.055  7.142   -5.831  1.00 42.66  ? 410 GLY A CA  1 
ATOM   2970  C C   . GLY A 1 410 ? 0.343   8.587   -5.930  1.00 49.85  ? 410 GLY A C   1 
ATOM   2971  O O   . GLY A 1 410 ? -0.355  9.404   -6.543  1.00 50.45  ? 410 GLY A O   1 
ATOM   2972  N N   . PRO A 1 411 ? 1.538   8.899   -5.405  1.00 44.70  ? 411 PRO A N   1 
ATOM   2973  C CA  . PRO A 1 411 ? 1.708   10.113  -4.590  1.00 37.35  ? 411 PRO A CA  1 
ATOM   2974  C C   . PRO A 1 411 ? 0.623   11.149  -4.841  1.00 42.78  ? 411 PRO A C   1 
ATOM   2975  O O   . PRO A 1 411 ? 0.506   11.674  -5.952  1.00 53.71  ? 411 PRO A O   1 
ATOM   2976  C CB  . PRO A 1 411 ? 3.103   10.621  -4.989  1.00 38.87  ? 411 PRO A CB  1 
ATOM   2977  C CG  . PRO A 1 411 ? 3.489   9.830   -6.205  1.00 40.08  ? 411 PRO A CG  1 
ATOM   2978  C CD  . PRO A 1 411 ? 2.791   8.513   -6.066  1.00 47.13  ? 411 PRO A CD  1 
ATOM   2979  N N   . GLY A 1 412 ? -0.197  11.422  -3.839  1.00 38.04  ? 412 GLY A N   1 
ATOM   2980  C CA  . GLY A 1 412 ? -1.236  12.422  -3.977  1.00 37.24  ? 412 GLY A CA  1 
ATOM   2981  C C   . GLY A 1 412 ? -2.333  12.215  -2.950  1.00 36.69  ? 412 GLY A C   1 
ATOM   2982  O O   . GLY A 1 412 ? -2.240  11.368  -2.050  1.00 28.55  ? 412 GLY A O   1 
ATOM   2983  N N   . ALA A 1 413 ? -3.377  13.027  -3.093  1.00 29.30  ? 413 ALA A N   1 
ATOM   2984  C CA  . ALA A 1 413 ? -4.563  12.838  -2.275  1.00 28.50  ? 413 ALA A CA  1 
ATOM   2985  C C   . ALA A 1 413 ? -5.337  11.653  -2.821  1.00 26.32  ? 413 ALA A C   1 
ATOM   2986  O O   . ALA A 1 413 ? -5.331  11.397  -4.027  1.00 33.89  ? 413 ALA A O   1 
ATOM   2987  C CB  . ALA A 1 413 ? -5.433  14.092  -2.267  1.00 28.84  ? 413 ALA A CB  1 
ATOM   2988  N N   . GLU A 1 414 ? -5.967  10.904  -1.930  1.00 27.97  ? 414 GLU A N   1 
ATOM   2989  C CA  . GLU A 1 414 ? -6.678  9.682   -2.289  1.00 31.29  ? 414 GLU A CA  1 
ATOM   2990  C C   . GLU A 1 414 ? -8.169  9.906   -2.099  1.00 25.17  ? 414 GLU A C   1 
ATOM   2991  O O   . GLU A 1 414 ? -8.609  10.318  -1.022  1.00 22.26  ? 414 GLU A O   1 
ATOM   2992  C CB  . GLU A 1 414 ? -6.196  8.491   -1.443  1.00 25.35  ? 414 GLU A CB  1 
ATOM   2993  C CG  . GLU A 1 414 ? -6.855  7.153   -1.763  1.00 32.39  ? 414 GLU A CG  1 
ATOM   2994  C CD  . GLU A 1 414 ? -6.486  6.006   -0.780  1.00 30.58  ? 414 GLU A CD  1 
ATOM   2995  O OE1 . GLU A 1 414 ? -5.986  6.276   0.332   1.00 30.30  ? 414 GLU A OE1 1 
ATOM   2996  O OE2 . GLU A 1 414 ? -6.697  4.830   -1.144  1.00 28.87  ? 414 GLU A OE2 1 
ATOM   2997  N N   . LEU A 1 415 ? -8.941  9.628   -3.137  1.00 23.98  ? 415 LEU A N   1 
ATOM   2998  C CA  . LEU A 1 415 ? -10.384 9.776   -3.072  1.00 28.53  ? 415 LEU A CA  1 
ATOM   2999  C C   . LEU A 1 415 ? -11.063 8.460   -3.424  1.00 29.35  ? 415 LEU A C   1 
ATOM   3000  O O   . LEU A 1 415 ? -10.563 7.683   -4.246  1.00 25.84  ? 415 LEU A O   1 
ATOM   3001  C CB  . LEU A 1 415 ? -10.864 10.883  -4.009  1.00 29.62  ? 415 LEU A CB  1 
ATOM   3002  C CG  . LEU A 1 415 ? -10.399 12.285  -3.605  1.00 30.46  ? 415 LEU A CG  1 
ATOM   3003  C CD1 . LEU A 1 415 ? -10.833 13.329  -4.617  1.00 35.63  ? 415 LEU A CD1 1 
ATOM   3004  C CD2 . LEU A 1 415 ? -10.964 12.621  -2.249  1.00 27.57  ? 415 LEU A CD2 1 
ATOM   3005  N N   . LEU A 1 416 ? -12.205 8.219   -2.776  1.00 28.09  ? 416 LEU A N   1 
ATOM   3006  C CA  . LEU A 1 416 ? -13.079 7.085   -3.051  1.00 24.52  ? 416 LEU A CA  1 
ATOM   3007  C C   . LEU A 1 416 ? -14.427 7.614   -3.534  1.00 25.31  ? 416 LEU A C   1 
ATOM   3008  O O   . LEU A 1 416 ? -15.075 8.395   -2.828  1.00 22.88  ? 416 LEU A O   1 
ATOM   3009  C CB  . LEU A 1 416 ? -13.247 6.235   -1.793  1.00 20.20  ? 416 LEU A CB  1 
ATOM   3010  C CG  . LEU A 1 416 ? -14.003 4.928   -1.969  1.00 26.79  ? 416 LEU A CG  1 
ATOM   3011  C CD1 . LEU A 1 416 ? -13.375 4.097   -3.064  1.00 24.79  ? 416 LEU A CD1 1 
ATOM   3012  C CD2 . LEU A 1 416 ? -14.053 4.162   -0.640  1.00 19.91  ? 416 LEU A CD2 1 
ATOM   3013  N N   . VAL A 1 417 ? -14.848 7.192   -4.730  1.00 24.90  ? 417 VAL A N   1 
ATOM   3014  C CA  . VAL A 1 417 ? -16.046 7.708   -5.385  1.00 25.24  ? 417 VAL A CA  1 
ATOM   3015  C C   . VAL A 1 417 ? -17.065 6.587   -5.531  1.00 29.00  ? 417 VAL A C   1 
ATOM   3016  O O   . VAL A 1 417 ? -16.705 5.462   -5.903  1.00 23.38  ? 417 VAL A O   1 
ATOM   3017  C CB  . VAL A 1 417 ? -15.734 8.313   -6.769  1.00 27.80  ? 417 VAL A CB  1 
ATOM   3018  C CG1 . VAL A 1 417 ? -16.955 9.083   -7.288  1.00 28.25  ? 417 VAL A CG1 1 
ATOM   3019  C CG2 . VAL A 1 417 ? -14.508 9.201   -6.706  1.00 26.64  ? 417 VAL A CG2 1 
ATOM   3020  N N   . PHE A 1 418 ? -18.346 6.920   -5.299  1.00 25.30  ? 418 PHE A N   1 
ATOM   3021  C CA  . PHE A 1 418 ? -19.470 5.987   -5.311  1.00 25.41  ? 418 PHE A CA  1 
ATOM   3022  C C   . PHE A 1 418 ? -20.516 6.416   -6.331  1.00 27.01  ? 418 PHE A C   1 
ATOM   3023  O O   . PHE A 1 418 ? -20.769 7.612   -6.504  1.00 28.26  ? 418 PHE A O   1 
ATOM   3024  C CB  . PHE A 1 418 ? -20.139 5.907   -3.931  1.00 24.79  ? 418 PHE A CB  1 
ATOM   3025  C CG  . PHE A 1 418 ? -19.289 5.250   -2.882  1.00 24.07  ? 418 PHE A CG  1 
ATOM   3026  C CD1 . PHE A 1 418 ? -19.253 3.876   -2.771  1.00 17.59  ? 418 PHE A CD1 1 
ATOM   3027  C CD2 . PHE A 1 418 ? -18.510 6.010   -2.017  1.00 24.93  ? 418 PHE A CD2 1 
ATOM   3028  C CE1 . PHE A 1 418 ? -18.463 3.272   -1.829  1.00 18.73  ? 418 PHE A CE1 1 
ATOM   3029  C CE2 . PHE A 1 418 ? -17.702 5.394   -1.046  1.00 19.85  ? 418 PHE A CE2 1 
ATOM   3030  C CZ  . PHE A 1 418 ? -17.684 4.032   -0.961  1.00 20.66  ? 418 PHE A CZ  1 
ATOM   3031  N N   . SER A 1 419 ? -21.144 5.440   -6.987  1.00 26.94  ? 419 SER A N   1 
ATOM   3032  C CA  . SER A 1 419 ? -22.281 5.709   -7.866  1.00 29.31  ? 419 SER A CA  1 
ATOM   3033  C C   . SER A 1 419 ? -23.069 4.432   -8.098  1.00 27.11  ? 419 SER A C   1 
ATOM   3034  O O   . SER A 1 419 ? -22.509 3.332   -8.100  1.00 29.23  ? 419 SER A O   1 
ATOM   3035  C CB  . SER A 1 419 ? -21.857 6.282   -9.221  1.00 33.49  ? 419 SER A CB  1 
ATOM   3036  O OG  . SER A 1 419 ? -23.005 6.632   -9.985  1.00 33.43  ? 419 SER A OG  1 
ATOM   3037  N N   . LYS A 1 420 ? -24.370 4.590   -8.312  1.00 29.23  ? 420 LYS A N   1 
ATOM   3038  C CA  . LYS A 1 420 ? -25.192 3.459   -8.728  1.00 32.32  ? 420 LYS A CA  1 
ATOM   3039  C C   . LYS A 1 420 ? -25.116 3.209   -10.229 1.00 31.20  ? 420 LYS A C   1 
ATOM   3040  O O   . LYS A 1 420 ? -25.776 2.294   -10.736 1.00 31.02  ? 420 LYS A O   1 
ATOM   3041  C CB  . LYS A 1 420 ? -26.657 3.668   -8.322  1.00 35.50  ? 420 LYS A CB  1 
ATOM   3042  C CG  . LYS A 1 420 ? -26.889 3.893   -6.836  1.00 39.52  ? 420 LYS A CG  1 
ATOM   3043  C CD  . LYS A 1 420 ? -28.358 4.200   -6.525  1.00 38.50  ? 420 LYS A CD  1 
ATOM   3044  C CE  . LYS A 1 420 ? -28.713 3.853   -5.090  1.00 44.75  ? 420 LYS A CE  1 
ATOM   3045  N NZ  . LYS A 1 420 ? -29.255 5.047   -4.354  1.00 51.33  ? 420 LYS A NZ  1 
ATOM   3046  N N   . ASP A 1 421 ? -24.323 3.980   -10.955 1.00 31.17  ? 421 ASP A N   1 
ATOM   3047  C CA  . ASP A 1 421 ? -24.231 3.818   -12.395 1.00 35.86  ? 421 ASP A CA  1 
ATOM   3048  C C   . ASP A 1 421 ? -22.786 4.023   -12.826 1.00 32.16  ? 421 ASP A C   1 
ATOM   3049  O O   . ASP A 1 421 ? -22.168 5.034   -12.485 1.00 29.51  ? 421 ASP A O   1 
ATOM   3050  C CB  . ASP A 1 421 ? -25.167 4.798   -13.116 1.00 33.78  ? 421 ASP A CB  1 
ATOM   3051  C CG  . ASP A 1 421 ? -25.039 4.705   -14.614 1.00 39.12  ? 421 ASP A CG  1 
ATOM   3052  O OD1 . ASP A 1 421 ? -25.711 3.843   -15.227 1.00 42.08  ? 421 ASP A OD1 1 
ATOM   3053  O OD2 . ASP A 1 421 ? -24.238 5.482   -15.175 1.00 37.41  ? 421 ASP A OD2 1 
ATOM   3054  N N   . TRP A 1 422 ? -22.247 3.052   -13.564 1.00 34.03  ? 422 TRP A N   1 
ATOM   3055  C CA  . TRP A 1 422 ? -20.819 3.058   -13.860 1.00 36.08  ? 422 TRP A CA  1 
ATOM   3056  C C   . TRP A 1 422 ? -20.405 4.248   -14.725 1.00 39.89  ? 422 TRP A C   1 
ATOM   3057  O O   . TRP A 1 422 ? -19.301 4.781   -14.555 1.00 36.89  ? 422 TRP A O   1 
ATOM   3058  C CB  . TRP A 1 422 ? -20.417 1.752   -14.543 1.00 39.27  ? 422 TRP A CB  1 
ATOM   3059  C CG  . TRP A 1 422 ? -19.012 1.785   -15.024 1.00 40.36  ? 422 TRP A CG  1 
ATOM   3060  C CD1 . TRP A 1 422 ? -18.584 1.753   -16.320 1.00 39.76  ? 422 TRP A CD1 1 
ATOM   3061  C CD2 . TRP A 1 422 ? -17.843 1.876   -14.213 1.00 42.10  ? 422 TRP A CD2 1 
ATOM   3062  N NE1 . TRP A 1 422 ? -17.216 1.808   -16.362 1.00 46.34  ? 422 TRP A NE1 1 
ATOM   3063  C CE2 . TRP A 1 422 ? -16.736 1.888   -15.081 1.00 41.15  ? 422 TRP A CE2 1 
ATOM   3064  C CE3 . TRP A 1 422 ? -17.624 1.946   -12.834 1.00 46.20  ? 422 TRP A CE3 1 
ATOM   3065  C CZ2 . TRP A 1 422 ? -15.423 1.973   -14.617 1.00 51.09  ? 422 TRP A CZ2 1 
ATOM   3066  C CZ3 . TRP A 1 422 ? -16.312 2.028   -12.371 1.00 49.62  ? 422 TRP A CZ3 1 
ATOM   3067  C CH2 . TRP A 1 422 ? -15.229 2.045   -13.263 1.00 46.89  ? 422 TRP A CH2 1 
ATOM   3068  N N   . ASP A 1 423 ? -21.254 4.670   -15.663 1.00 36.79  ? 423 ASP A N   1 
ATOM   3069  C CA  . ASP A 1 423 ? -20.875 5.786   -16.518 1.00 38.31  ? 423 ASP A CA  1 
ATOM   3070  C C   . ASP A 1 423 ? -20.961 7.113   -15.769 1.00 39.32  ? 423 ASP A C   1 
ATOM   3071  O O   . ASP A 1 423 ? -20.185 8.034   -16.043 1.00 35.10  ? 423 ASP A O   1 
ATOM   3072  C CB  . ASP A 1 423 ? -21.751 5.797   -17.778 1.00 39.46  ? 423 ASP A CB  1 
ATOM   3073  C CG  . ASP A 1 423 ? -21.365 4.692   -18.767 1.00 43.87  ? 423 ASP A CG  1 
ATOM   3074  O OD1 . ASP A 1 423 ? -20.154 4.439   -18.951 1.00 50.36  ? 423 ASP A OD1 1 
ATOM   3075  O OD2 . ASP A 1 423 ? -22.266 4.050   -19.343 1.00 43.79  ? 423 ASP A OD2 1 
ATOM   3076  N N   . ARG A 1 424 ? -21.860 7.226   -14.794 1.00 33.93  ? 424 ARG A N   1 
ATOM   3077  C CA  . ARG A 1 424 ? -21.872 8.441   -14.002 1.00 33.21  ? 424 ARG A CA  1 
ATOM   3078  C C   . ARG A 1 424 ? -20.669 8.498   -13.069 1.00 35.88  ? 424 ARG A C   1 
ATOM   3079  O O   . ARG A 1 424 ? -20.192 9.589   -12.739 1.00 34.08  ? 424 ARG A O   1 
ATOM   3080  C CB  . ARG A 1 424 ? -23.208 8.551   -13.268 1.00 38.14  ? 424 ARG A CB  1 
ATOM   3081  C CG  . ARG A 1 424 ? -24.371 8.618   -14.284 1.00 39.68  ? 424 ARG A CG  1 
ATOM   3082  C CD  . ARG A 1 424 ? -25.730 8.935   -13.685 1.00 44.86  ? 424 ARG A CD  1 
ATOM   3083  N NE  . ARG A 1 424 ? -26.132 7.962   -12.678 1.00 42.17  ? 424 ARG A NE  1 
ATOM   3084  C CZ  . ARG A 1 424 ? -26.161 8.228   -11.383 1.00 40.21  ? 424 ARG A CZ  1 
ATOM   3085  N NH1 . ARG A 1 424 ? -25.867 9.435   -10.926 1.00 42.47  ? 424 ARG A NH1 1 
ATOM   3086  N NH2 . ARG A 1 424 ? -26.504 7.267   -10.526 1.00 32.81  ? 424 ARG A NH2 1 
ATOM   3087  N N   . LEU A 1 425 ? -20.130 7.338   -12.693 1.00 35.13  ? 425 LEU A N   1 
ATOM   3088  C CA  . LEU A 1 425 ? -18.913 7.309   -11.893 1.00 32.88  ? 425 LEU A CA  1 
ATOM   3089  C C   . LEU A 1 425 ? -17.744 7.864   -12.682 1.00 35.46  ? 425 LEU A C   1 
ATOM   3090  O O   . LEU A 1 425 ? -16.936 8.636   -12.156 1.00 36.34  ? 425 LEU A O   1 
ATOM   3091  C CB  . LEU A 1 425 ? -18.602 5.877   -11.464 1.00 33.70  ? 425 LEU A CB  1 
ATOM   3092  C CG  . LEU A 1 425 ? -17.986 5.618   -10.091 1.00 35.27  ? 425 LEU A CG  1 
ATOM   3093  C CD1 . LEU A 1 425 ? -17.772 4.108   -9.912  1.00 32.12  ? 425 LEU A CD1 1 
ATOM   3094  C CD2 . LEU A 1 425 ? -16.690 6.387   -9.852  1.00 30.57  ? 425 LEU A CD2 1 
ATOM   3095  N N   . THR A 1 426 ? -17.622 7.446   -13.942 1.00 34.17  ? 426 THR A N   1 
ATOM   3096  C CA  . THR A 1 426 ? -16.552 7.954   -14.788 1.00 37.39  ? 426 THR A CA  1 
ATOM   3097  C C   . THR A 1 426 ? -16.643 9.467   -14.928 1.00 37.08  ? 426 THR A C   1 
ATOM   3098  O O   . THR A 1 426 ? -15.622 10.164  -14.873 1.00 38.05  ? 426 THR A O   1 
ATOM   3099  C CB  . THR A 1 426 ? -16.614 7.267   -16.151 1.00 35.79  ? 426 THR A CB  1 
ATOM   3100  O OG1 . THR A 1 426 ? -16.087 5.944   -16.016 1.00 42.51  ? 426 THR A OG1 1 
ATOM   3101  C CG2 . THR A 1 426 ? -15.801 8.027   -17.178 1.00 36.87  ? 426 THR A CG2 1 
ATOM   3102  N N   . ALA A 1 427 ? -17.867 9.992   -15.064 1.00 39.34  ? 427 ALA A N   1 
ATOM   3103  C CA  . ALA A 1 427 ? -18.058 11.433  -15.193 1.00 35.37  ? 427 ALA A CA  1 
ATOM   3104  C C   . ALA A 1 427 ? -17.605 12.156  -13.936 1.00 33.70  ? 427 ALA A C   1 
ATOM   3105  O O   . ALA A 1 427 ? -16.900 13.163  -14.010 1.00 31.60  ? 427 ALA A O   1 
ATOM   3106  C CB  . ALA A 1 427 ? -19.528 11.747  -15.489 1.00 35.65  ? 427 ALA A CB  1 
ATOM   3107  N N   . MET A 1 428 ? -18.015 11.655  -12.765 1.00 36.06  ? 428 MET A N   1 
ATOM   3108  C CA  . MET A 1 428 ? -17.581 12.266  -11.516 1.00 32.64  ? 428 MET A CA  1 
ATOM   3109  C C   . MET A 1 428 ? -16.069 12.323  -11.450 1.00 34.27  ? 428 MET A C   1 
ATOM   3110  O O   . MET A 1 428 ? -15.499 13.353  -11.082 1.00 33.95  ? 428 MET A O   1 
ATOM   3111  C CB  . MET A 1 428 ? -18.122 11.485  -10.319 1.00 34.50  ? 428 MET A CB  1 
ATOM   3112  C CG  . MET A 1 428 ? -19.482 11.914  -9.852  1.00 38.91  ? 428 MET A CG  1 
ATOM   3113  S SD  . MET A 1 428 ? -20.210 10.720  -8.721  1.00 43.68  ? 428 MET A SD  1 
ATOM   3114  C CE  . MET A 1 428 ? -21.194 9.777   -9.865  1.00 38.78  ? 428 MET A CE  1 
ATOM   3115  N N   . LYS A 1 429 ? -15.404 11.228  -11.834 1.00 31.58  ? 429 LYS A N   1 
ATOM   3116  C CA  . LYS A 1 429 ? -13.950 11.191  -11.801 1.00 33.70  ? 429 LYS A CA  1 
ATOM   3117  C C   . LYS A 1 429 ? -13.335 12.223  -12.727 1.00 29.97  ? 429 LYS A C   1 
ATOM   3118  O O   . LYS A 1 429 ? -12.292 12.790  -12.397 1.00 34.69  ? 429 LYS A O   1 
ATOM   3119  C CB  . LYS A 1 429 ? -13.446 9.791   -12.148 1.00 34.52  ? 429 LYS A CB  1 
ATOM   3120  C CG  . LYS A 1 429 ? -13.389 8.872   -10.938 1.00 37.10  ? 429 LYS A CG  1 
ATOM   3121  C CD  . LYS A 1 429 ? -13.612 7.427   -11.323 1.00 36.82  ? 429 LYS A CD  1 
ATOM   3122  C CE  . LYS A 1 429 ? -12.322 6.763   -11.692 1.00 36.66  ? 429 LYS A CE  1 
ATOM   3123  N NZ  . LYS A 1 429 ? -11.287 7.083   -10.686 1.00 40.31  ? 429 LYS A NZ  1 
ATOM   3124  N N   . ASP A 1 430 ? -13.956 12.488  -13.879 1.00 34.52  ? 430 ASP A N   1 
ATOM   3125  C CA  . ASP A 1 430 ? -13.475 13.568  -14.745 1.00 39.70  ? 430 ASP A CA  1 
ATOM   3126  C C   . ASP A 1 430 ? -13.581 14.922  -14.056 1.00 36.06  ? 430 ASP A C   1 
ATOM   3127  O O   . ASP A 1 430 ? -12.636 15.719  -14.075 1.00 39.34  ? 430 ASP A O   1 
ATOM   3128  C CB  . ASP A 1 430 ? -14.262 13.598  -16.051 1.00 40.09  ? 430 ASP A CB  1 
ATOM   3129  C CG  . ASP A 1 430 ? -14.079 12.357  -16.846 1.00 43.33  ? 430 ASP A CG  1 
ATOM   3130  O OD1 . ASP A 1 430 ? -12.950 11.818  -16.813 1.00 51.03  ? 430 ASP A OD1 1 
ATOM   3131  O OD2 . ASP A 1 430 ? -15.054 11.919  -17.494 1.00 47.08  ? 430 ASP A OD2 1 
ATOM   3132  N N   . GLU A 1 431 ? -14.739 15.209  -13.461 1.00 37.90  ? 431 GLU A N   1 
ATOM   3133  C CA  . GLU A 1 431 ? -14.937 16.515  -12.845 1.00 37.14  ? 431 GLU A CA  1 
ATOM   3134  C C   . GLU A 1 431 ? -14.052 16.700  -11.623 1.00 36.23  ? 431 GLU A C   1 
ATOM   3135  O O   . GLU A 1 431 ? -13.605 17.819  -11.360 1.00 41.97  ? 431 GLU A O   1 
ATOM   3136  C CB  . GLU A 1 431 ? -16.411 16.709  -12.485 1.00 40.08  ? 431 GLU A CB  1 
ATOM   3137  C CG  . GLU A 1 431 ? -17.298 16.887  -13.712 1.00 45.51  ? 431 GLU A CG  1 
ATOM   3138  C CD  . GLU A 1 431 ? -18.508 17.760  -13.442 1.00 54.92  ? 431 GLU A CD  1 
ATOM   3139  O OE1 . GLU A 1 431 ? -18.346 18.799  -12.763 1.00 49.97  ? 431 GLU A OE1 1 
ATOM   3140  O OE2 . GLU A 1 431 ? -19.622 17.404  -13.905 1.00 64.13  ? 431 GLU A OE2 1 
ATOM   3141  N N   . ILE A 1 432 ? -13.780 15.631  -10.868 1.00 34.15  ? 432 ILE A N   1 
ATOM   3142  C CA  . ILE A 1 432 ? -12.817 15.732  -9.773  1.00 33.28  ? 432 ILE A CA  1 
ATOM   3143  C C   . ILE A 1 432 ? -11.445 16.097  -10.325 1.00 34.40  ? 432 ILE A C   1 
ATOM   3144  O O   . ILE A 1 432 ? -10.771 17.012  -9.830  1.00 33.19  ? 432 ILE A O   1 
ATOM   3145  C CB  . ILE A 1 432 ? -12.737 14.410  -8.994  1.00 33.08  ? 432 ILE A CB  1 
ATOM   3146  C CG1 . ILE A 1 432 ? -14.096 13.934  -8.498  1.00 30.79  ? 432 ILE A CG1 1 
ATOM   3147  C CG2 . ILE A 1 432 ? -11.744 14.569  -7.861  1.00 27.71  ? 432 ILE A CG2 1 
ATOM   3148  C CD1 . ILE A 1 432 ? -14.241 13.881  -6.992  1.00 34.84  ? 432 ILE A CD1 1 
ATOM   3149  N N   . ALA A 1 433 ? -11.003 15.352  -11.349 1.00 31.38  ? 433 ALA A N   1 
ATOM   3150  C CA  . ALA A 1 433 ? -9.718  15.618  -11.994 1.00 40.93  ? 433 ALA A CA  1 
ATOM   3151  C C   . ALA A 1 433 ? -9.662  17.035  -12.537 1.00 40.60  ? 433 ALA A C   1 
ATOM   3152  O O   . ALA A 1 433 ? -8.635  17.717  -12.430 1.00 41.15  ? 433 ALA A O   1 
ATOM   3153  C CB  . ALA A 1 433 ? -9.479  14.614  -13.123 1.00 38.25  ? 433 ALA A CB  1 
ATOM   3154  N N   . THR A 1 434 ? -10.770 17.498  -13.107 1.00 40.13  ? 434 THR A N   1 
ATOM   3155  C CA  . THR A 1 434 ? -10.844 18.855  -13.630 1.00 40.34  ? 434 THR A CA  1 
ATOM   3156  C C   . THR A 1 434 ? -10.707 19.888  -12.515 1.00 38.83  ? 434 THR A C   1 
ATOM   3157  O O   . THR A 1 434 ? -9.882  20.805  -12.603 1.00 40.65  ? 434 THR A O   1 
ATOM   3158  C CB  . THR A 1 434 ? -12.160 19.016  -14.394 1.00 35.74  ? 434 THR A CB  1 
ATOM   3159  O OG1 . THR A 1 434 ? -12.044 18.358  -15.667 1.00 40.98  ? 434 THR A OG1 1 
ATOM   3160  C CG2 . THR A 1 434 ? -12.506 20.476  -14.606 1.00 42.94  ? 434 THR A CG2 1 
ATOM   3161  N N   . THR A 1 435 ? -11.483 19.731  -11.442 1.00 34.66  ? 435 THR A N   1 
ATOM   3162  C CA  . THR A 1 435 ? -11.617 20.736  -10.388 1.00 35.38  ? 435 THR A CA  1 
ATOM   3163  C C   . THR A 1 435 ? -10.595 20.574  -9.253  1.00 38.54  ? 435 THR A C   1 
ATOM   3164  O O   . THR A 1 435 ? -10.131 21.572  -8.685  1.00 33.35  ? 435 THR A O   1 
ATOM   3165  C CB  . THR A 1 435 ? -13.051 20.686  -9.831  1.00 39.93  ? 435 THR A CB  1 
ATOM   3166  O OG1 . THR A 1 435 ? -13.957 21.319  -10.755 1.00 45.93  ? 435 THR A OG1 1 
ATOM   3167  C CG2 . THR A 1 435 ? -13.160 21.367  -8.485  1.00 30.16  ? 435 THR A CG2 1 
ATOM   3168  N N   . ALA A 1 436 ? -10.238 19.347  -8.880  1.00 32.46  ? 436 ALA A N   1 
ATOM   3169  C CA  . ALA A 1 436 ? -9.209  19.199  -7.861  1.00 33.49  ? 436 ALA A CA  1 
ATOM   3170  C C   . ALA A 1 436 ? -7.818  19.083  -8.456  1.00 36.23  ? 436 ALA A C   1 
ATOM   3171  O O   . ALA A 1 436 ? -6.850  19.483  -7.806  1.00 42.85  ? 436 ALA A O   1 
ATOM   3172  C CB  . ALA A 1 436 ? -9.492  17.985  -6.970  1.00 35.01  ? 436 ALA A CB  1 
ATOM   3173  N N   . GLY A 1 437 ? -7.696  18.573  -9.677  1.00 40.23  ? 437 GLY A N   1 
ATOM   3174  C CA  . GLY A 1 437 ? -6.406  18.392  -10.314 1.00 41.03  ? 437 GLY A CA  1 
ATOM   3175  C C   . GLY A 1 437 ? -5.836  16.999  -10.098 1.00 45.63  ? 437 GLY A C   1 
ATOM   3176  O O   . GLY A 1 437 ? -6.184  16.285  -9.158  1.00 46.27  ? 437 GLY A O   1 
ATOM   3177  N N   . THR A 1 438 ? -4.943  16.606  -11.007 1.00 46.82  ? 438 THR A N   1 
ATOM   3178  C CA  . THR A 1 438 ? -4.228  15.339  -10.912 1.00 50.24  ? 438 THR A CA  1 
ATOM   3179  C C   . THR A 1 438 ? -2.741  15.575  -11.141 1.00 53.66  ? 438 THR A C   1 
ATOM   3180  O O   . THR A 1 438 ? -2.347  16.526  -11.823 1.00 56.17  ? 438 THR A O   1 
ATOM   3181  C CB  . THR A 1 438 ? -4.746  14.294  -11.929 1.00 47.34  ? 438 THR A CB  1 
ATOM   3182  O OG1 . THR A 1 438 ? -4.681  14.830  -13.259 1.00 52.82  ? 438 THR A OG1 1 
ATOM   3183  C CG2 . THR A 1 438 ? -6.171  13.895  -11.616 1.00 43.29  ? 438 THR A CG2 1 
ATOM   3184  N N   . LEU A 1 439 ? -1.915  14.696  -10.571 1.00 53.47  ? 439 LEU A N   1 
ATOM   3185  C CA  . LEU A 1 439 ? -0.463  14.784  -10.735 1.00 57.15  ? 439 LEU A CA  1 
ATOM   3186  C C   . LEU A 1 439 ? 0.022   14.167  -12.043 1.00 60.50  ? 439 LEU A C   1 
ATOM   3187  O O   . LEU A 1 439 ? 1.042   13.471  -12.074 1.00 63.99  ? 439 LEU A O   1 
ATOM   3188  C CB  . LEU A 1 439 ? 0.228   14.145  -9.530  1.00 49.37  ? 439 LEU A CB  1 
ATOM   3189  C CG  . LEU A 1 439 ? 0.241   15.075  -8.309  1.00 52.27  ? 439 LEU A CG  1 
ATOM   3190  C CD1 . LEU A 1 439 ? 1.174   14.601  -7.205  1.00 47.90  ? 439 LEU A CD1 1 
ATOM   3191  C CD2 . LEU A 1 439 ? 0.625   16.479  -8.741  1.00 52.67  ? 439 LEU A CD2 1 
ATOM   3192  N N   . SER A 1 440 ? -0.710  14.423  -13.126 1.00 63.50  ? 440 SER A N   1 
ATOM   3193  C CA  . SER A 1 440 ? -0.367  14.005  -14.487 1.00 73.32  ? 440 SER A CA  1 
ATOM   3194  C C   . SER A 1 440 ? -0.500  12.490  -14.649 1.00 75.23  ? 440 SER A C   1 
ATOM   3195  O O   . SER A 1 440 ? 0.485   11.747  -14.622 1.00 74.75  ? 440 SER A O   1 
ATOM   3196  C CB  . SER A 1 440 ? 1.049   14.474  -14.864 1.00 72.79  ? 440 SER A CB  1 
ATOM   3197  O OG  . SER A 1 440 ? 1.138   14.760  -16.249 1.00 76.56  ? 440 SER A OG  1 
ATOM   3198  N N   . PRO B 1 2   ? 8.603   -52.759 -14.554 1.00 41.98  ? 2   PRO B N   1 
ATOM   3199  C CA  . PRO B 1 2   ? 9.797   -52.580 -13.726 1.00 35.75  ? 2   PRO B CA  1 
ATOM   3200  C C   . PRO B 1 2   ? 9.898   -51.158 -13.158 1.00 40.41  ? 2   PRO B C   1 
ATOM   3201  O O   . PRO B 1 2   ? 9.075   -50.309 -13.496 1.00 39.45  ? 2   PRO B O   1 
ATOM   3202  C CB  . PRO B 1 2   ? 10.940  -52.865 -14.704 1.00 44.10  ? 2   PRO B CB  1 
ATOM   3203  C CG  . PRO B 1 2   ? 10.353  -53.802 -15.714 1.00 40.85  ? 2   PRO B CG  1 
ATOM   3204  C CD  . PRO B 1 2   ? 8.901   -53.441 -15.830 1.00 40.20  ? 2   PRO B CD  1 
ATOM   3205  N N   . LYS B 1 3   ? 10.908  -50.893 -12.332 1.00 33.87  ? 3   LYS B N   1 
ATOM   3206  C CA  . LYS B 1 3   ? 11.076  -49.560 -11.783 1.00 35.95  ? 3   LYS B CA  1 
ATOM   3207  C C   . LYS B 1 3   ? 12.557  -49.249 -11.645 1.00 31.70  ? 3   LYS B C   1 
ATOM   3208  O O   . LYS B 1 3   ? 13.382  -50.139 -11.448 1.00 31.48  ? 3   LYS B O   1 
ATOM   3209  C CB  . LYS B 1 3   ? 10.360  -49.419 -10.420 1.00 35.68  ? 3   LYS B CB  1 
ATOM   3210  C CG  . LYS B 1 3   ? 10.997  -50.219 -9.266  1.00 32.85  ? 3   LYS B CG  1 
ATOM   3211  C CD  . LYS B 1 3   ? 10.386  -49.900 -7.880  1.00 34.96  ? 3   LYS B CD  1 
ATOM   3212  C CE  . LYS B 1 3   ? 10.902  -50.846 -6.783  1.00 26.05  ? 3   LYS B CE  1 
ATOM   3213  N NZ  . LYS B 1 3   ? 10.554  -52.248 -7.127  1.00 26.42  ? 3   LYS B NZ  1 
ATOM   3214  N N   . ILE B 1 4   ? 12.882  -47.971 -11.740 1.00 30.69  ? 4   ILE B N   1 
ATOM   3215  C CA  . ILE B 1 4   ? 14.217  -47.490 -11.421 1.00 33.91  ? 4   ILE B CA  1 
ATOM   3216  C C   . ILE B 1 4   ? 14.218  -47.070 -9.956  1.00 28.61  ? 4   ILE B C   1 
ATOM   3217  O O   . ILE B 1 4   ? 13.450  -46.190 -9.564  1.00 31.84  ? 4   ILE B O   1 
ATOM   3218  C CB  . ILE B 1 4   ? 14.610  -46.318 -12.332 1.00 34.66  ? 4   ILE B CB  1 
ATOM   3219  C CG1 . ILE B 1 4   ? 14.461  -46.708 -13.803 1.00 37.80  ? 4   ILE B CG1 1 
ATOM   3220  C CG2 . ILE B 1 4   ? 16.015  -45.851 -12.027 1.00 34.44  ? 4   ILE B CG2 1 
ATOM   3221  C CD1 . ILE B 1 4   ? 14.582  -45.521 -14.745 1.00 39.05  ? 4   ILE B CD1 1 
ATOM   3222  N N   . ILE B 1 5   ? 15.071  -47.687 -9.145  1.00 25.87  ? 5   ILE B N   1 
ATOM   3223  C CA  . ILE B 1 5   ? 15.218  -47.303 -7.743  1.00 28.42  ? 5   ILE B CA  1 
ATOM   3224  C C   . ILE B 1 5   ? 16.312  -46.251 -7.661  1.00 33.36  ? 5   ILE B C   1 
ATOM   3225  O O   . ILE B 1 5   ? 17.457  -46.502 -8.064  1.00 31.69  ? 5   ILE B O   1 
ATOM   3226  C CB  . ILE B 1 5   ? 15.554  -48.509 -6.854  1.00 31.47  ? 5   ILE B CB  1 
ATOM   3227  C CG1 . ILE B 1 5   ? 14.519  -49.610 -7.020  1.00 25.87  ? 5   ILE B CG1 1 
ATOM   3228  C CG2 . ILE B 1 5   ? 15.678  -48.096 -5.369  1.00 28.28  ? 5   ILE B CG2 1 
ATOM   3229  C CD1 . ILE B 1 5   ? 15.134  -50.945 -6.971  1.00 31.26  ? 5   ILE B CD1 1 
ATOM   3230  N N   . LEU B 1 6   ? 15.971  -45.082 -7.111  1.00 33.98  ? 6   LEU B N   1 
ATOM   3231  C CA  . LEU B 1 6   ? 16.820  -43.895 -7.191  1.00 31.80  ? 6   LEU B CA  1 
ATOM   3232  C C   . LEU B 1 6   ? 17.036  -43.293 -5.809  1.00 33.86  ? 6   LEU B C   1 
ATOM   3233  O O   . LEU B 1 6   ? 16.250  -42.453 -5.344  1.00 35.10  ? 6   LEU B O   1 
ATOM   3234  C CB  . LEU B 1 6   ? 16.218  -42.871 -8.151  1.00 33.83  ? 6   LEU B CB  1 
ATOM   3235  C CG  . LEU B 1 6   ? 17.148  -41.842 -8.798  1.00 30.48  ? 6   LEU B CG  1 
ATOM   3236  C CD1 . LEU B 1 6   ? 17.750  -42.446 -10.040 1.00 32.58  ? 6   LEU B CD1 1 
ATOM   3237  C CD2 . LEU B 1 6   ? 16.365  -40.596 -9.155  1.00 30.88  ? 6   LEU B CD2 1 
ATOM   3238  N N   . PRO B 1 7   ? 18.096  -43.679 -5.136  1.00 36.88  ? 7   PRO B N   1 
ATOM   3239  C CA  . PRO B 1 7   ? 18.466  -43.038 -3.858  1.00 34.67  ? 7   PRO B CA  1 
ATOM   3240  C C   . PRO B 1 7   ? 19.186  -41.701 -4.027  1.00 35.37  ? 7   PRO B C   1 
ATOM   3241  O O   . PRO B 1 7   ? 20.400  -41.592 -3.903  1.00 37.24  ? 7   PRO B O   1 
ATOM   3242  C CB  . PRO B 1 7   ? 19.379  -44.086 -3.218  1.00 33.69  ? 7   PRO B CB  1 
ATOM   3243  C CG  . PRO B 1 7   ? 20.018  -44.771 -4.376  1.00 34.92  ? 7   PRO B CG  1 
ATOM   3244  C CD  . PRO B 1 7   ? 19.022  -44.765 -5.502  1.00 35.52  ? 7   PRO B CD  1 
ATOM   3245  N N   . ASN B 1 8   ? 18.409  -40.648 -4.297  1.00 37.11  ? 8   ASN B N   1 
ATOM   3246  C CA  . ASN B 1 8   ? 18.939  -39.287 -4.477  1.00 32.76  ? 8   ASN B CA  1 
ATOM   3247  C C   . ASN B 1 8   ? 18.748  -38.422 -3.232  1.00 31.84  ? 8   ASN B C   1 
ATOM   3248  O O   . ASN B 1 8   ? 19.270  -38.729 -2.161  1.00 37.11  ? 8   ASN B O   1 
ATOM   3249  C CB  . ASN B 1 8   ? 18.254  -38.602 -5.660  1.00 32.85  ? 8   ASN B CB  1 
ATOM   3250  C CG  . ASN B 1 8   ? 16.751  -38.492 -5.462  1.00 34.57  ? 8   ASN B CG  1 
ATOM   3251  O OD1 . ASN B 1 8   ? 16.132  -39.405 -4.926  1.00 34.43  ? 8   ASN B OD1 1 
ATOM   3252  N ND2 . ASN B 1 8   ? 16.165  -37.369 -5.868  1.00 31.70  ? 8   ASN B ND2 1 
ATOM   3253  N N   . THR B 1 27  ? 33.799  -39.446 -3.588  1.00 77.66  ? 27  THR B N   1 
ATOM   3254  C CA  . THR B 1 27  ? 33.220  -40.560 -4.330  1.00 79.21  ? 27  THR B CA  1 
ATOM   3255  C C   . THR B 1 27  ? 33.025  -41.760 -3.402  1.00 78.78  ? 27  THR B C   1 
ATOM   3256  O O   . THR B 1 27  ? 32.935  -41.592 -2.180  1.00 79.55  ? 27  THR B O   1 
ATOM   3257  C CB  . THR B 1 27  ? 34.099  -40.965 -5.543  1.00 79.03  ? 27  THR B CB  1 
ATOM   3258  O OG1 . THR B 1 27  ? 35.261  -41.675 -5.093  1.00 79.63  ? 27  THR B OG1 1 
ATOM   3259  C CG2 . THR B 1 27  ? 34.532  -39.732 -6.332  1.00 74.77  ? 27  THR B CG2 1 
ATOM   3260  N N   . ALA B 1 28  ? 32.973  -42.957 -3.997  1.00 73.61  ? 28  ALA B N   1 
ATOM   3261  C CA  . ALA B 1 28  ? 32.641  -44.204 -3.307  1.00 74.04  ? 28  ALA B CA  1 
ATOM   3262  C C   . ALA B 1 28  ? 33.338  -44.361 -1.960  1.00 72.12  ? 28  ALA B C   1 
ATOM   3263  O O   . ALA B 1 28  ? 32.713  -44.761 -0.970  1.00 61.58  ? 28  ALA B O   1 
ATOM   3264  C CB  . ALA B 1 28  ? 32.998  -45.403 -4.191  1.00 64.70  ? 28  ALA B CB  1 
ATOM   3265  N N   . SER B 1 29  ? 34.636  -44.048 -1.925  1.00 77.40  ? 29  SER B N   1 
ATOM   3266  C CA  . SER B 1 29  ? 35.518  -44.405 -0.818  1.00 74.04  ? 29  SER B CA  1 
ATOM   3267  C C   . SER B 1 29  ? 35.345  -45.884 -0.479  1.00 71.27  ? 29  SER B C   1 
ATOM   3268  O O   . SER B 1 29  ? 35.643  -46.312 0.641   1.00 64.88  ? 29  SER B O   1 
ATOM   3269  C CB  . SER B 1 29  ? 35.264  -43.518 0.403   1.00 71.51  ? 29  SER B CB  1 
ATOM   3270  O OG  . SER B 1 29  ? 36.422  -43.450 1.218   1.00 76.47  ? 29  SER B OG  1 
ATOM   3271  N N   . SER B 1 30  ? 34.885  -46.671 -1.463  1.00 69.73  ? 30  SER B N   1 
ATOM   3272  C CA  . SER B 1 30  ? 34.623  -48.108 -1.314  1.00 66.47  ? 30  SER B CA  1 
ATOM   3273  C C   . SER B 1 30  ? 33.558  -48.397 -0.248  1.00 63.08  ? 30  SER B C   1 
ATOM   3274  O O   . SER B 1 30  ? 33.632  -49.392 0.479   1.00 62.59  ? 30  SER B O   1 
ATOM   3275  C CB  . SER B 1 30  ? 35.916  -48.887 -1.035  1.00 66.03  ? 30  SER B CB  1 
ATOM   3276  O OG  . SER B 1 30  ? 36.727  -48.267 -0.043  1.00 73.56  ? 30  SER B OG  1 
ATOM   3277  N N   . THR B 1 31  ? 32.542  -47.546 -0.166  1.00 50.62  ? 31  THR B N   1 
ATOM   3278  C CA  . THR B 1 31  ? 31.406  -47.803 0.706   1.00 47.43  ? 31  THR B CA  1 
ATOM   3279  C C   . THR B 1 31  ? 30.249  -48.395 -0.094  1.00 46.07  ? 31  THR B C   1 
ATOM   3280  O O   . THR B 1 31  ? 30.196  -48.288 -1.319  1.00 47.08  ? 31  THR B O   1 
ATOM   3281  C CB  . THR B 1 31  ? 30.974  -46.521 1.420   1.00 50.10  ? 31  THR B CB  1 
ATOM   3282  O OG1 . THR B 1 31  ? 30.727  -45.488 0.454   1.00 63.36  ? 31  THR B OG1 1 
ATOM   3283  C CG2 . THR B 1 31  ? 32.061  -46.060 2.370   1.00 53.32  ? 31  THR B CG2 1 
ATOM   3284  N N   . ASP B 1 32  ? 29.328  -49.051 0.611   1.00 42.43  ? 32  ASP B N   1 
ATOM   3285  C CA  . ASP B 1 32  ? 28.182  -49.688 -0.035  1.00 42.63  ? 32  ASP B CA  1 
ATOM   3286  C C   . ASP B 1 32  ? 26.883  -49.243 0.622   1.00 39.81  ? 32  ASP B C   1 
ATOM   3287  O O   . ASP B 1 32  ? 25.925  -50.015 0.768   1.00 31.57  ? 32  ASP B O   1 
ATOM   3288  C CB  . ASP B 1 32  ? 28.326  -51.216 -0.055  1.00 35.28  ? 32  ASP B CB  1 
ATOM   3289  C CG  . ASP B 1 32  ? 28.184  -51.847 1.307   1.00 37.69  ? 32  ASP B CG  1 
ATOM   3290  O OD1 . ASP B 1 32  ? 28.291  -51.130 2.321   1.00 41.51  ? 32  ASP B OD1 1 
ATOM   3291  O OD2 . ASP B 1 32  ? 27.977  -53.079 1.369   1.00 38.54  ? 32  ASP B OD2 1 
ATOM   3292  N N   . THR B 1 33  ? 26.834  -47.962 0.985   1.00 38.89  ? 33  THR B N   1 
ATOM   3293  C CA  . THR B 1 33  ? 25.710  -47.428 1.747   1.00 38.83  ? 33  THR B CA  1 
ATOM   3294  C C   . THR B 1 33  ? 24.389  -47.588 1.008   1.00 35.71  ? 33  THR B C   1 
ATOM   3295  O O   . THR B 1 33  ? 23.382  -47.987 1.602   1.00 38.38  ? 33  THR B O   1 
ATOM   3296  C CB  . THR B 1 33  ? 25.945  -45.957 2.077   1.00 43.95  ? 33  THR B CB  1 
ATOM   3297  O OG1 . THR B 1 33  ? 27.279  -45.774 2.570   1.00 48.43  ? 33  THR B OG1 1 
ATOM   3298  C CG2 . THR B 1 33  ? 24.935  -45.491 3.097   1.00 43.28  ? 33  THR B CG2 1 
ATOM   3299  N N   . THR B 1 34  ? 24.354  -47.255 -0.271  1.00 36.30  ? 34  THR B N   1 
ATOM   3300  C CA  . THR B 1 34  ? 23.084  -47.280 -0.983  1.00 42.93  ? 34  THR B CA  1 
ATOM   3301  C C   . THR B 1 34  ? 22.794  -48.637 -1.595  1.00 40.79  ? 34  THR B C   1 
ATOM   3302  O O   . THR B 1 34  ? 21.801  -48.780 -2.320  1.00 38.92  ? 34  THR B O   1 
ATOM   3303  C CB  . THR B 1 34  ? 23.029  -46.173 -2.048  1.00 36.35  ? 34  THR B CB  1 
ATOM   3304  O OG1 . THR B 1 34  ? 23.940  -46.466 -3.112  1.00 43.70  ? 34  THR B OG1 1 
ATOM   3305  C CG2 . THR B 1 34  ? 23.387  -44.851 -1.409  1.00 35.06  ? 34  THR B CG2 1 
ATOM   3306  N N   . ALA B 1 35  ? 23.622  -49.642 -1.301  1.00 35.33  ? 35  ALA B N   1 
ATOM   3307  C CA  . ALA B 1 35  ? 23.277  -50.985 -1.735  1.00 36.60  ? 35  ALA B CA  1 
ATOM   3308  C C   . ALA B 1 35  ? 22.074  -51.506 -0.973  1.00 35.53  ? 35  ALA B C   1 
ATOM   3309  O O   . ALA B 1 35  ? 21.367  -52.390 -1.473  1.00 29.40  ? 35  ALA B O   1 
ATOM   3310  C CB  . ALA B 1 35  ? 24.462  -51.932 -1.563  1.00 37.74  ? 35  ALA B CB  1 
ATOM   3311  N N   . ARG B 1 36  ? 21.821  -50.960 0.220   1.00 32.92  ? 36  ARG B N   1 
ATOM   3312  C CA  . ARG B 1 36  ? 20.671  -51.386 0.999   1.00 29.68  ? 36  ARG B CA  1 
ATOM   3313  C C   . ARG B 1 36  ? 19.389  -51.323 0.195   1.00 31.57  ? 36  ARG B C   1 
ATOM   3314  O O   . ARG B 1 36  ? 18.441  -52.050 0.499   1.00 35.01  ? 36  ARG B O   1 
ATOM   3315  C CB  . ARG B 1 36  ? 20.532  -50.525 2.247   1.00 33.16  ? 36  ARG B CB  1 
ATOM   3316  C CG  . ARG B 1 36  ? 20.232  -49.063 1.968   1.00 29.41  ? 36  ARG B CG  1 
ATOM   3317  C CD  . ARG B 1 36  ? 20.636  -48.214 3.152   1.00 30.01  ? 36  ARG B CD  1 
ATOM   3318  N NE  . ARG B 1 36  ? 19.993  -48.600 4.411   1.00 29.74  ? 36  ARG B NE  1 
ATOM   3319  C CZ  . ARG B 1 36  ? 18.798  -48.181 4.821   1.00 32.72  ? 36  ARG B CZ  1 
ATOM   3320  N NH1 . ARG B 1 36  ? 18.000  -47.460 4.037   1.00 21.65  ? 36  ARG B NH1 1 
ATOM   3321  N NH2 . ARG B 1 36  ? 18.400  -48.474 6.058   1.00 28.15  ? 36  ARG B NH2 1 
ATOM   3322  N N   . PHE B 1 37  ? 19.341  -50.497 -0.843  1.00 28.63  ? 37  PHE B N   1 
ATOM   3323  C CA  . PHE B 1 37  ? 18.075  -50.307 -1.533  1.00 37.87  ? 37  PHE B CA  1 
ATOM   3324  C C   . PHE B 1 37  ? 17.770  -51.422 -2.528  1.00 31.84  ? 37  PHE B C   1 
ATOM   3325  O O   . PHE B 1 37  ? 16.662  -51.459 -3.074  1.00 28.76  ? 37  PHE B O   1 
ATOM   3326  C CB  . PHE B 1 37  ? 18.074  -48.923 -2.190  1.00 29.21  ? 37  PHE B CB  1 
ATOM   3327  C CG  . PHE B 1 37  ? 18.200  -47.812 -1.196  1.00 30.91  ? 37  PHE B CG  1 
ATOM   3328  C CD1 . PHE B 1 37  ? 17.271  -47.687 -0.175  1.00 30.10  ? 37  PHE B CD1 1 
ATOM   3329  C CD2 . PHE B 1 37  ? 19.241  -46.905 -1.261  1.00 33.61  ? 37  PHE B CD2 1 
ATOM   3330  C CE1 . PHE B 1 37  ? 17.373  -46.673 0.767   1.00 30.71  ? 37  PHE B CE1 1 
ATOM   3331  C CE2 . PHE B 1 37  ? 19.352  -45.882 -0.323  1.00 34.75  ? 37  PHE B CE2 1 
ATOM   3332  C CZ  . PHE B 1 37  ? 18.414  -45.771 0.698   1.00 31.01  ? 37  PHE B CZ  1 
ATOM   3333  N N   . LEU B 1 38  ? 18.709  -52.344 -2.736  1.00 32.45  ? 38  LEU B N   1 
ATOM   3334  C CA  . LEU B 1 38  ? 18.457  -53.528 -3.553  1.00 34.40  ? 38  LEU B CA  1 
ATOM   3335  C C   . LEU B 1 38  ? 17.276  -54.345 -3.042  1.00 32.61  ? 38  LEU B C   1 
ATOM   3336  O O   . LEU B 1 38  ? 16.582  -54.986 -3.839  1.00 33.75  ? 38  LEU B O   1 
ATOM   3337  C CB  . LEU B 1 38  ? 19.711  -54.403 -3.598  1.00 34.94  ? 38  LEU B CB  1 
ATOM   3338  C CG  . LEU B 1 38  ? 20.521  -54.312 -4.892  1.00 38.00  ? 38  LEU B CG  1 
ATOM   3339  C CD1 . LEU B 1 38  ? 21.660  -55.298 -4.882  1.00 40.08  ? 38  LEU B CD1 1 
ATOM   3340  C CD2 . LEU B 1 38  ? 19.618  -54.554 -6.090  1.00 36.34  ? 38  LEU B CD2 1 
ATOM   3341  N N   . TRP B 1 39  ? 17.034  -54.347 -1.724  1.00 28.41  ? 39  TRP B N   1 
ATOM   3342  C CA  . TRP B 1 39  ? 15.904  -55.074 -1.157  1.00 29.26  ? 39  TRP B CA  1 
ATOM   3343  C C   . TRP B 1 39  ? 14.556  -54.518 -1.605  1.00 31.46  ? 39  TRP B C   1 
ATOM   3344  O O   . TRP B 1 39  ? 13.519  -55.101 -1.267  1.00 28.89  ? 39  TRP B O   1 
ATOM   3345  C CB  . TRP B 1 39  ? 15.985  -55.058 0.360   1.00 31.64  ? 39  TRP B CB  1 
ATOM   3346  C CG  . TRP B 1 39  ? 17.119  -55.847 0.883   1.00 28.42  ? 39  TRP B CG  1 
ATOM   3347  C CD1 . TRP B 1 39  ? 18.357  -55.387 1.185   1.00 31.36  ? 39  TRP B CD1 1 
ATOM   3348  C CD2 . TRP B 1 39  ? 17.126  -57.242 1.155   1.00 29.50  ? 39  TRP B CD2 1 
ATOM   3349  N NE1 . TRP B 1 39  ? 19.145  -56.414 1.640   1.00 31.38  ? 39  TRP B NE1 1 
ATOM   3350  C CE2 . TRP B 1 39  ? 18.411  -57.567 1.628   1.00 33.11  ? 39  TRP B CE2 1 
ATOM   3351  C CE3 . TRP B 1 39  ? 16.167  -58.255 1.047   1.00 31.78  ? 39  TRP B CE3 1 
ATOM   3352  C CZ2 . TRP B 1 39  ? 18.771  -58.868 1.986   1.00 30.04  ? 39  TRP B CZ2 1 
ATOM   3353  C CZ3 . TRP B 1 39  ? 16.522  -59.542 1.407   1.00 28.27  ? 39  TRP B CZ3 1 
ATOM   3354  C CH2 . TRP B 1 39  ? 17.811  -59.837 1.873   1.00 28.81  ? 39  TRP B CH2 1 
ATOM   3355  N N   . HIS B 1 40  ? 14.549  -53.409 -2.344  1.00 26.99  ? 40  HIS B N   1 
ATOM   3356  C CA  . HIS B 1 40  ? 13.345  -52.894 -2.974  1.00 30.43  ? 40  HIS B CA  1 
ATOM   3357  C C   . HIS B 1 40  ? 13.057  -53.547 -4.317  1.00 32.19  ? 40  HIS B C   1 
ATOM   3358  O O   . HIS B 1 40  ? 12.005  -53.272 -4.894  1.00 24.76  ? 40  HIS B O   1 
ATOM   3359  C CB  . HIS B 1 40  ? 13.474  -51.391 -3.208  1.00 26.39  ? 40  HIS B CB  1 
ATOM   3360  C CG  . HIS B 1 40  ? 12.979  -50.547 -2.082  1.00 23.33  ? 40  HIS B CG  1 
ATOM   3361  N ND1 . HIS B 1 40  ? 11.708  -50.660 -1.578  1.00 25.30  ? 40  HIS B ND1 1 
ATOM   3362  C CD2 . HIS B 1 40  ? 13.567  -49.537 -1.396  1.00 31.75  ? 40  HIS B CD2 1 
ATOM   3363  C CE1 . HIS B 1 40  ? 11.534  -49.770 -0.616  1.00 29.32  ? 40  HIS B CE1 1 
ATOM   3364  N NE2 . HIS B 1 40  ? 12.646  -49.072 -0.490  1.00 30.10  ? 40  HIS B NE2 1 
ATOM   3365  N N   . ALA B 1 41  ? 13.970  -54.371 -4.839  1.00 31.47  ? 41  ALA B N   1 
ATOM   3366  C CA  . ALA B 1 41  ? 13.917  -54.770 -6.239  1.00 32.74  ? 41  ALA B CA  1 
ATOM   3367  C C   . ALA B 1 41  ? 12.904  -55.878 -6.471  1.00 30.55  ? 41  ALA B C   1 
ATOM   3368  O O   . ALA B 1 41  ? 12.645  -56.714 -5.598  1.00 31.90  ? 41  ALA B O   1 
ATOM   3369  C CB  . ALA B 1 41  ? 15.292  -55.228 -6.739  1.00 31.57  ? 41  ALA B CB  1 
ATOM   3370  N N   . GLU B 1 42  ? 12.313  -55.854 -7.663  1.00 29.40  ? 42  GLU B N   1 
ATOM   3371  C CA  . GLU B 1 42  ? 11.510  -56.937 -8.206  1.00 33.30  ? 42  GLU B CA  1 
ATOM   3372  C C   . GLU B 1 42  ? 12.025  -57.222 -9.606  1.00 38.21  ? 42  GLU B C   1 
ATOM   3373  O O   . GLU B 1 42  ? 12.866  -56.490 -10.135 1.00 39.73  ? 42  GLU B O   1 
ATOM   3374  C CB  . GLU B 1 42  ? 10.007  -56.601 -8.252  1.00 34.96  ? 42  GLU B CB  1 
ATOM   3375  C CG  . GLU B 1 42  ? 9.351   -56.374 -6.896  1.00 33.77  ? 42  GLU B CG  1 
ATOM   3376  C CD  . GLU B 1 42  ? 8.772   -57.648 -6.282  1.00 46.45  ? 42  GLU B CD  1 
ATOM   3377  O OE1 . GLU B 1 42  ? 9.038   -58.756 -6.813  1.00 42.46  ? 42  GLU B OE1 1 
ATOM   3378  O OE2 . GLU B 1 42  ? 8.059   -57.528 -5.255  1.00 43.92  ? 42  GLU B OE2 1 
ATOM   3379  N N   . ASP B 1 43  ? 11.506  -58.299 -10.200 1.00 37.34  ? 43  ASP B N   1 
ATOM   3380  C CA  . ASP B 1 43  ? 11.927  -58.748 -11.519 1.00 41.68  ? 43  ASP B CA  1 
ATOM   3381  C C   . ASP B 1 43  ? 11.972  -57.594 -12.506 1.00 35.57  ? 43  ASP B C   1 
ATOM   3382  O O   . ASP B 1 43  ? 10.974  -56.900 -12.716 1.00 39.02  ? 43  ASP B O   1 
ATOM   3383  C CB  . ASP B 1 43  ? 10.975  -59.849 -12.020 1.00 40.34  ? 43  ASP B CB  1 
ATOM   3384  C CG  . ASP B 1 43  ? 11.289  -61.221 -11.414 1.00 44.04  ? 43  ASP B CG  1 
ATOM   3385  O OD1 . ASP B 1 43  ? 12.051  -61.273 -10.425 1.00 41.17  ? 43  ASP B OD1 1 
ATOM   3386  O OD2 . ASP B 1 43  ? 10.771  -62.244 -11.917 1.00 47.36  ? 43  ASP B OD2 1 
ATOM   3387  N N   . GLY B 1 44  ? 13.135  -57.389 -13.110 1.00 36.94  ? 44  GLY B N   1 
ATOM   3388  C CA  . GLY B 1 44  ? 13.278  -56.414 -14.170 1.00 41.31  ? 44  GLY B CA  1 
ATOM   3389  C C   . GLY B 1 44  ? 13.680  -55.027 -13.727 1.00 36.99  ? 44  GLY B C   1 
ATOM   3390  O O   . GLY B 1 44  ? 13.851  -54.150 -14.581 1.00 44.31  ? 44  GLY B O   1 
ATOM   3391  N N   . ASP B 1 45  ? 13.855  -54.801 -12.431 1.00 35.18  ? 45  ASP B N   1 
ATOM   3392  C CA  . ASP B 1 45  ? 14.118  -53.459 -11.943 1.00 36.09  ? 45  ASP B CA  1 
ATOM   3393  C C   . ASP B 1 45  ? 15.557  -53.032 -12.188 1.00 43.54  ? 45  ASP B C   1 
ATOM   3394  O O   . ASP B 1 45  ? 16.480  -53.845 -12.268 1.00 40.99  ? 45  ASP B O   1 
ATOM   3395  C CB  . ASP B 1 45  ? 13.842  -53.359 -10.454 1.00 33.38  ? 45  ASP B CB  1 
ATOM   3396  C CG  . ASP B 1 45  ? 12.388  -53.206 -10.157 1.00 34.30  ? 45  ASP B CG  1 
ATOM   3397  O OD1 . ASP B 1 45  ? 11.591  -53.182 -11.121 1.00 36.19  ? 45  ASP B OD1 1 
ATOM   3398  O OD2 . ASP B 1 45  ? 12.047  -53.110 -8.960  1.00 33.81  ? 45  ASP B OD2 1 
ATOM   3399  N N   . VAL B 1 46  ? 15.736  -51.718 -12.243 1.00 41.03  ? 46  VAL B N   1 
ATOM   3400  C CA  . VAL B 1 46  ? 17.037  -51.082 -12.331 1.00 33.21  ? 46  VAL B CA  1 
ATOM   3401  C C   . VAL B 1 46  ? 17.313  -50.391 -11.008 1.00 38.69  ? 46  VAL B C   1 
ATOM   3402  O O   . VAL B 1 46  ? 16.404  -49.802 -10.412 1.00 39.95  ? 46  VAL B O   1 
ATOM   3403  C CB  . VAL B 1 46  ? 17.049  -50.084 -13.499 1.00 35.01  ? 46  VAL B CB  1 
ATOM   3404  C CG1 . VAL B 1 46  ? 18.239  -49.151 -13.399 1.00 41.03  ? 46  VAL B CG1 1 
ATOM   3405  C CG2 . VAL B 1 46  ? 17.030  -50.843 -14.812 1.00 41.67  ? 46  VAL B CG2 1 
ATOM   3406  N N   . LEU B 1 47  ? 18.558  -50.464 -10.540 1.00 38.76  ? 47  LEU B N   1 
ATOM   3407  C CA  . LEU B 1 47  ? 18.975  -49.770 -9.327  1.00 37.62  ? 47  LEU B CA  1 
ATOM   3408  C C   . LEU B 1 47  ? 20.173  -48.896 -9.644  1.00 41.53  ? 47  LEU B C   1 
ATOM   3409  O O   . LEU B 1 47  ? 21.226  -49.407 -10.038 1.00 48.11  ? 47  LEU B O   1 
ATOM   3410  C CB  . LEU B 1 47  ? 19.341  -50.749 -8.214  1.00 40.20  ? 47  LEU B CB  1 
ATOM   3411  C CG  . LEU B 1 47  ? 20.110  -50.048 -7.090  1.00 38.99  ? 47  LEU B CG  1 
ATOM   3412  C CD1 . LEU B 1 47  ? 19.211  -49.078 -6.329  1.00 38.74  ? 47  LEU B CD1 1 
ATOM   3413  C CD2 . LEU B 1 47  ? 20.693  -51.056 -6.155  1.00 41.40  ? 47  LEU B CD2 1 
ATOM   3414  N N   . VAL B 1 48  ? 20.018  -47.589 -9.456  1.00 40.11  ? 48  VAL B N   1 
ATOM   3415  C CA  . VAL B 1 48  ? 21.096  -46.630 -9.669  1.00 40.02  ? 48  VAL B CA  1 
ATOM   3416  C C   . VAL B 1 48  ? 21.843  -46.426 -8.361  1.00 44.55  ? 48  VAL B C   1 
ATOM   3417  O O   . VAL B 1 48  ? 21.229  -46.216 -7.312  1.00 48.01  ? 48  VAL B O   1 
ATOM   3418  C CB  . VAL B 1 48  ? 20.549  -45.293 -10.194 1.00 43.59  ? 48  VAL B CB  1 
ATOM   3419  C CG1 . VAL B 1 48  ? 21.694  -44.386 -10.622 1.00 36.75  ? 48  VAL B CG1 1 
ATOM   3420  C CG2 . VAL B 1 48  ? 19.576  -45.532 -11.354 1.00 44.40  ? 48  VAL B CG2 1 
ATOM   3421  N N   . ILE B 1 49  ? 23.168  -46.490 -8.413  1.00 47.48  ? 49  ILE B N   1 
ATOM   3422  C CA  . ILE B 1 49  ? 23.973  -46.282 -7.213  1.00 48.93  ? 49  ILE B CA  1 
ATOM   3423  C C   . ILE B 1 49  ? 25.139  -45.328 -7.478  1.00 49.36  ? 49  ILE B C   1 
ATOM   3424  O O   . ILE B 1 49  ? 25.849  -45.459 -8.488  1.00 49.66  ? 49  ILE B O   1 
ATOM   3425  C CB  . ILE B 1 49  ? 24.466  -47.628 -6.643  1.00 49.68  ? 49  ILE B CB  1 
ATOM   3426  C CG1 . ILE B 1 49  ? 25.600  -48.216 -7.478  1.00 47.11  ? 49  ILE B CG1 1 
ATOM   3427  C CG2 . ILE B 1 49  ? 23.364  -48.654 -6.580  1.00 50.94  ? 49  ILE B CG2 1 
ATOM   3428  C CD1 . ILE B 1 49  ? 26.388  -49.250 -6.736  1.00 53.10  ? 49  ILE B CD1 1 
ATOM   3429  N N   . PRO B 1 50  ? 25.386  -44.352 -6.593  1.00 52.31  ? 50  PRO B N   1 
ATOM   3430  C CA  . PRO B 1 50  ? 26.749  -43.817 -6.484  1.00 53.20  ? 50  PRO B CA  1 
ATOM   3431  C C   . PRO B 1 50  ? 27.577  -44.904 -5.831  1.00 59.43  ? 50  PRO B C   1 
ATOM   3432  O O   . PRO B 1 50  ? 27.186  -46.068 -5.929  1.00 60.15  ? 50  PRO B O   1 
ATOM   3433  C CB  . PRO B 1 50  ? 26.582  -42.577 -5.604  1.00 48.47  ? 50  PRO B CB  1 
ATOM   3434  C CG  . PRO B 1 50  ? 25.420  -42.914 -4.737  1.00 49.65  ? 50  PRO B CG  1 
ATOM   3435  C CD  . PRO B 1 50  ? 24.486  -43.758 -5.588  1.00 53.55  ? 50  PRO B CD  1 
ATOM   3436  N N   . ASP B 1 51  ? 28.665  -44.569 -5.140  1.00 59.00  ? 51  ASP B N   1 
ATOM   3437  C CA  . ASP B 1 51  ? 29.501  -45.540 -4.427  1.00 55.60  ? 51  ASP B CA  1 
ATOM   3438  C C   . ASP B 1 51  ? 29.538  -46.951 -5.028  1.00 55.42  ? 51  ASP B C   1 
ATOM   3439  O O   . ASP B 1 51  ? 29.446  -47.118 -6.251  1.00 53.84  ? 51  ASP B O   1 
ATOM   3440  C CB  . ASP B 1 51  ? 29.119  -45.567 -2.931  1.00 55.85  ? 51  ASP B CB  1 
ATOM   3441  C CG  . ASP B 1 51  ? 27.692  -46.048 -2.647  1.00 53.13  ? 51  ASP B CG  1 
ATOM   3442  O OD1 . ASP B 1 51  ? 26.970  -46.560 -3.521  1.00 52.13  ? 51  ASP B OD1 1 
ATOM   3443  O OD2 . ASP B 1 51  ? 27.275  -45.884 -1.481  1.00 55.99  ? 51  ASP B OD2 1 
ATOM   3444  N N   . THR B 1 52  ? 29.719  -47.975 -4.202  1.00 51.09  ? 52  THR B N   1 
ATOM   3445  C CA  . THR B 1 52  ? 30.116  -49.270 -4.736  1.00 52.74  ? 52  THR B CA  1 
ATOM   3446  C C   . THR B 1 52  ? 29.416  -50.386 -3.983  1.00 51.39  ? 52  THR B C   1 
ATOM   3447  O O   . THR B 1 52  ? 29.003  -50.223 -2.836  1.00 53.46  ? 52  THR B O   1 
ATOM   3448  C CB  . THR B 1 52  ? 31.636  -49.460 -4.652  1.00 52.85  ? 52  THR B CB  1 
ATOM   3449  O OG1 . THR B 1 52  ? 32.054  -50.428 -5.622  1.00 50.36  ? 52  THR B OG1 1 
ATOM   3450  C CG2 . THR B 1 52  ? 32.044  -49.926 -3.256  1.00 49.15  ? 52  THR B CG2 1 
ATOM   3451  N N   . VAL B 1 53  ? 29.289  -51.527 -4.641  1.00 46.69  ? 53  VAL B N   1 
ATOM   3452  C CA  . VAL B 1 53  ? 28.622  -52.683 -4.060  1.00 45.58  ? 53  VAL B CA  1 
ATOM   3453  C C   . VAL B 1 53  ? 29.358  -53.940 -4.497  1.00 40.98  ? 53  VAL B C   1 
ATOM   3454  O O   . VAL B 1 53  ? 29.728  -54.081 -5.668  1.00 38.36  ? 53  VAL B O   1 
ATOM   3455  C CB  . VAL B 1 53  ? 27.131  -52.737 -4.465  1.00 47.63  ? 53  VAL B CB  1 
ATOM   3456  C CG1 . VAL B 1 53  ? 26.981  -52.721 -5.988  1.00 46.01  ? 53  VAL B CG1 1 
ATOM   3457  C CG2 . VAL B 1 53  ? 26.461  -53.973 -3.870  1.00 36.69  ? 53  VAL B CG2 1 
ATOM   3458  N N   . ASP B 1 54  ? 29.597  -54.833 -3.538  1.00 33.58  ? 54  ASP B N   1 
ATOM   3459  C CA  . ASP B 1 54  ? 30.000  -56.212 -3.778  1.00 37.96  ? 54  ASP B CA  1 
ATOM   3460  C C   . ASP B 1 54  ? 29.230  -56.800 -4.960  1.00 41.53  ? 54  ASP B C   1 
ATOM   3461  O O   . ASP B 1 54  ? 27.999  -56.685 -5.025  1.00 45.37  ? 54  ASP B O   1 
ATOM   3462  C CB  . ASP B 1 54  ? 29.763  -57.017 -2.500  1.00 39.77  ? 54  ASP B CB  1 
ATOM   3463  C CG  . ASP B 1 54  ? 30.216  -58.465 -2.601  1.00 41.76  ? 54  ASP B CG  1 
ATOM   3464  O OD1 . ASP B 1 54  ? 30.069  -59.082 -3.674  1.00 41.52  ? 54  ASP B OD1 1 
ATOM   3465  O OD2 . ASP B 1 54  ? 30.702  -58.995 -1.572  1.00 41.42  ? 54  ASP B OD2 1 
ATOM   3466  N N   . PRO B 1 55  ? 29.906  -57.431 -5.920  1.00 44.21  ? 55  PRO B N   1 
ATOM   3467  C CA  . PRO B 1 55  ? 29.167  -58.036 -7.043  1.00 46.13  ? 55  PRO B CA  1 
ATOM   3468  C C   . PRO B 1 55  ? 28.315  -59.229 -6.640  1.00 43.86  ? 55  PRO B C   1 
ATOM   3469  O O   . PRO B 1 55  ? 27.433  -59.626 -7.415  1.00 48.94  ? 55  PRO B O   1 
ATOM   3470  C CB  . PRO B 1 55  ? 30.270  -58.438 -8.034  1.00 47.60  ? 55  PRO B CB  1 
ATOM   3471  C CG  . PRO B 1 55  ? 31.556  -58.406 -7.258  1.00 46.14  ? 55  PRO B CG  1 
ATOM   3472  C CD  . PRO B 1 55  ? 31.370  -57.537 -6.056  1.00 43.02  ? 55  PRO B CD  1 
ATOM   3473  N N   . ASP B 1 56  ? 28.531  -59.805 -5.454  1.00 38.62  ? 56  ASP B N   1 
ATOM   3474  C CA  . ASP B 1 56  ? 27.681  -60.900 -4.997  1.00 43.59  ? 56  ASP B CA  1 
ATOM   3475  C C   . ASP B 1 56  ? 26.372  -60.413 -4.401  1.00 37.51  ? 56  ASP B C   1 
ATOM   3476  O O   . ASP B 1 56  ? 25.410  -61.185 -4.330  1.00 36.70  ? 56  ASP B O   1 
ATOM   3477  C CB  . ASP B 1 56  ? 28.413  -61.746 -3.956  1.00 40.83  ? 56  ASP B CB  1 
ATOM   3478  C CG  . ASP B 1 56  ? 29.346  -62.744 -4.587  1.00 40.90  ? 56  ASP B CG  1 
ATOM   3479  O OD1 . ASP B 1 56  ? 29.419  -62.772 -5.830  1.00 43.97  ? 56  ASP B OD1 1 
ATOM   3480  O OD2 . ASP B 1 56  ? 29.999  -63.500 -3.855  1.00 42.83  ? 56  ASP B OD2 1 
ATOM   3481  N N   . PHE B 1 57  ? 26.324  -59.149 -3.993  1.00 39.28  ? 57  PHE B N   1 
ATOM   3482  C CA  . PHE B 1 57  ? 25.199  -58.650 -3.209  1.00 39.67  ? 57  PHE B CA  1 
ATOM   3483  C C   . PHE B 1 57  ? 23.874  -58.737 -3.951  1.00 35.11  ? 57  PHE B C   1 
ATOM   3484  O O   . PHE B 1 57  ? 22.890  -59.191 -3.338  1.00 37.32  ? 57  PHE B O   1 
ATOM   3485  C CB  . PHE B 1 57  ? 25.512  -57.212 -2.750  1.00 39.34  ? 57  PHE B CB  1 
ATOM   3486  C CG  . PHE B 1 57  ? 24.552  -56.660 -1.745  1.00 32.30  ? 57  PHE B CG  1 
ATOM   3487  C CD1 . PHE B 1 57  ? 24.637  -57.014 -0.417  1.00 31.66  ? 57  PHE B CD1 1 
ATOM   3488  C CD2 . PHE B 1 57  ? 23.577  -55.751 -2.132  1.00 40.30  ? 57  PHE B CD2 1 
ATOM   3489  C CE1 . PHE B 1 57  ? 23.757  -56.497 0.515   1.00 31.15  ? 57  PHE B CE1 1 
ATOM   3490  C CE2 . PHE B 1 57  ? 22.692  -55.227 -1.210  1.00 34.86  ? 57  PHE B CE2 1 
ATOM   3491  C CZ  . PHE B 1 57  ? 22.785  -55.607 0.121   1.00 39.78  ? 57  PHE B CZ  1 
ATOM   3492  N N   . PRO B 1 58  ? 23.766  -58.359 -5.229  1.00 32.22  ? 58  PRO B N   1 
ATOM   3493  C CA  . PRO B 1 58  ? 22.485  -58.580 -5.930  1.00 34.99  ? 58  PRO B CA  1 
ATOM   3494  C C   . PRO B 1 58  ? 22.007  -60.027 -5.887  1.00 35.77  ? 58  PRO B C   1 
ATOM   3495  O O   . PRO B 1 58  ? 20.844  -60.280 -5.539  1.00 33.78  ? 58  PRO B O   1 
ATOM   3496  C CB  . PRO B 1 58  ? 22.784  -58.111 -7.362  1.00 35.89  ? 58  PRO B CB  1 
ATOM   3497  C CG  . PRO B 1 58  ? 23.932  -57.180 -7.240  1.00 37.94  ? 58  PRO B CG  1 
ATOM   3498  C CD  . PRO B 1 58  ? 24.747  -57.659 -6.079  1.00 35.75  ? 58  PRO B CD  1 
ATOM   3499  N N   . GLY B 1 59  ? 22.877  -60.989 -6.215  1.00 31.11  ? 59  GLY B N   1 
ATOM   3500  C CA  . GLY B 1 59  ? 22.428  -62.370 -6.285  1.00 26.20  ? 59  GLY B CA  1 
ATOM   3501  C C   . GLY B 1 59  ? 21.931  -62.871 -4.943  1.00 31.47  ? 59  GLY B C   1 
ATOM   3502  O O   . GLY B 1 59  ? 20.891  -63.527 -4.854  1.00 31.20  ? 59  GLY B O   1 
ATOM   3503  N N   . TYR B 1 60  ? 22.650  -62.528 -3.878  1.00 32.44  ? 60  TYR B N   1 
ATOM   3504  C CA  . TYR B 1 60  ? 22.246  -62.920 -2.543  1.00 24.44  ? 60  TYR B CA  1 
ATOM   3505  C C   . TYR B 1 60  ? 20.863  -62.373 -2.205  1.00 29.75  ? 60  TYR B C   1 
ATOM   3506  O O   . TYR B 1 60  ? 20.009  -63.108 -1.687  1.00 24.70  ? 60  TYR B O   1 
ATOM   3507  C CB  . TYR B 1 60  ? 23.309  -62.457 -1.551  1.00 23.71  ? 60  TYR B CB  1 
ATOM   3508  C CG  . TYR B 1 60  ? 22.804  -62.174 -0.170  1.00 22.25  ? 60  TYR B CG  1 
ATOM   3509  C CD1 . TYR B 1 60  ? 22.582  -63.198 0.735   1.00 24.07  ? 60  TYR B CD1 1 
ATOM   3510  C CD2 . TYR B 1 60  ? 22.575  -60.869 0.248   1.00 29.92  ? 60  TYR B CD2 1 
ATOM   3511  C CE1 . TYR B 1 60  ? 22.115  -62.926 2.020   1.00 23.91  ? 60  TYR B CE1 1 
ATOM   3512  C CE2 . TYR B 1 60  ? 22.130  -60.593 1.527   1.00 22.42  ? 60  TYR B CE2 1 
ATOM   3513  C CZ  . TYR B 1 60  ? 21.898  -61.616 2.400   1.00 21.95  ? 60  TYR B CZ  1 
ATOM   3514  O OH  . TYR B 1 60  ? 21.437  -61.315 3.659   1.00 26.54  ? 60  TYR B OH  1 
ATOM   3515  N N   . VAL B 1 61  ? 20.606  -61.100 -2.540  1.00 29.15  ? 61  VAL B N   1 
ATOM   3516  C CA  . VAL B 1 61  ? 19.312  -60.492 -2.236  1.00 29.05  ? 61  VAL B CA  1 
ATOM   3517  C C   . VAL B 1 61  ? 18.220  -61.117 -3.093  1.00 28.34  ? 61  VAL B C   1 
ATOM   3518  O O   . VAL B 1 61  ? 17.105  -61.355 -2.619  1.00 29.44  ? 61  VAL B O   1 
ATOM   3519  C CB  . VAL B 1 61  ? 19.379  -58.960 -2.412  1.00 34.15  ? 61  VAL B CB  1 
ATOM   3520  C CG1 . VAL B 1 61  ? 17.974  -58.341 -2.589  1.00 28.01  ? 61  VAL B CG1 1 
ATOM   3521  C CG2 . VAL B 1 61  ? 20.090  -58.335 -1.228  1.00 33.18  ? 61  VAL B CG2 1 
ATOM   3522  N N   . ALA B 1 62  ? 18.525  -61.409 -4.360  1.00 31.54  ? 62  ALA B N   1 
ATOM   3523  C CA  . ALA B 1 62  ? 17.608  -62.194 -5.183  1.00 32.90  ? 62  ALA B CA  1 
ATOM   3524  C C   . ALA B 1 62  ? 17.366  -63.575 -4.578  1.00 36.56  ? 62  ALA B C   1 
ATOM   3525  O O   . ALA B 1 62  ? 16.222  -64.044 -4.516  1.00 34.83  ? 62  ALA B O   1 
ATOM   3526  C CB  . ALA B 1 62  ? 18.160  -62.319 -6.603  1.00 36.18  ? 62  ALA B CB  1 
ATOM   3527  N N   . ASP B 1 63  ? 18.440  -64.250 -4.135  1.00 37.55  ? 63  ASP B N   1 
ATOM   3528  C CA  . ASP B 1 63  ? 18.299  -65.549 -3.475  1.00 33.74  ? 63  ASP B CA  1 
ATOM   3529  C C   . ASP B 1 63  ? 17.330  -65.454 -2.312  1.00 29.98  ? 63  ASP B C   1 
ATOM   3530  O O   . ASP B 1 63  ? 16.389  -66.242 -2.190  1.00 28.94  ? 63  ASP B O   1 
ATOM   3531  C CB  . ASP B 1 63  ? 19.650  -66.046 -2.941  1.00 34.89  ? 63  ASP B CB  1 
ATOM   3532  C CG  . ASP B 1 63  ? 20.510  -66.733 -3.994  1.00 43.12  ? 63  ASP B CG  1 
ATOM   3533  O OD1 . ASP B 1 63  ? 20.031  -66.978 -5.130  1.00 42.41  ? 63  ASP B OD1 1 
ATOM   3534  O OD2 . ASP B 1 63  ? 21.677  -67.060 -3.654  1.00 41.16  ? 63  ASP B OD2 1 
ATOM   3535  N N   . THR B 1 64  ? 17.575  -64.498 -1.426  1.00 32.03  ? 64  THR B N   1 
ATOM   3536  C CA  . THR B 1 64  ? 16.795  -64.404 -0.205  1.00 33.44  ? 64  THR B CA  1 
ATOM   3537  C C   . THR B 1 64  ? 15.375  -63.939 -0.493  1.00 29.19  ? 64  THR B C   1 
ATOM   3538  O O   . THR B 1 64  ? 14.430  -64.361 0.180   1.00 33.59  ? 64  THR B O   1 
ATOM   3539  C CB  . THR B 1 64  ? 17.494  -63.458 0.758   1.00 31.82  ? 64  THR B CB  1 
ATOM   3540  O OG1 . THR B 1 64  ? 18.885  -63.787 0.778   1.00 31.30  ? 64  THR B OG1 1 
ATOM   3541  C CG2 . THR B 1 64  ? 16.906  -63.592 2.163   1.00 28.67  ? 64  THR B CG2 1 
ATOM   3542  N N   . LEU B 1 65  ? 15.208  -63.065 -1.484  1.00 34.13  ? 65  LEU B N   1 
ATOM   3543  C CA  . LEU B 1 65  ? 13.892  -62.545 -1.820  1.00 32.85  ? 65  LEU B CA  1 
ATOM   3544  C C   . LEU B 1 65  ? 13.107  -63.480 -2.731  1.00 39.03  ? 65  LEU B C   1 
ATOM   3545  O O   . LEU B 1 65  ? 11.876  -63.392 -2.775  1.00 32.51  ? 65  LEU B O   1 
ATOM   3546  C CB  . LEU B 1 65  ? 14.040  -61.172 -2.467  1.00 31.36  ? 65  LEU B CB  1 
ATOM   3547  C CG  . LEU B 1 65  ? 14.178  -60.076 -1.417  1.00 29.71  ? 65  LEU B CG  1 
ATOM   3548  C CD1 . LEU B 1 65  ? 14.286  -58.684 -2.043  1.00 31.91  ? 65  LEU B CD1 1 
ATOM   3549  C CD2 . LEU B 1 65  ? 12.983  -60.158 -0.468  1.00 31.18  ? 65  LEU B CD2 1 
ATOM   3550  N N   . GLY B 1 66  ? 13.781  -64.382 -3.439  1.00 38.53  ? 66  GLY B N   1 
ATOM   3551  C CA  . GLY B 1 66  ? 13.083  -65.292 -4.326  1.00 36.17  ? 66  GLY B CA  1 
ATOM   3552  C C   . GLY B 1 66  ? 12.656  -64.660 -5.627  1.00 31.55  ? 66  GLY B C   1 
ATOM   3553  O O   . GLY B 1 66  ? 11.562  -64.938 -6.121  1.00 40.37  ? 66  GLY B O   1 
ATOM   3554  N N   . ILE B 1 67  ? 13.487  -63.802 -6.196  1.00 38.25  ? 67  ILE B N   1 
ATOM   3555  C CA  . ILE B 1 67  ? 13.196  -63.204 -7.486  1.00 33.93  ? 67  ILE B CA  1 
ATOM   3556  C C   . ILE B 1 67  ? 14.325  -63.574 -8.428  1.00 36.87  ? 67  ILE B C   1 
ATOM   3557  O O   . ILE B 1 67  ? 15.402  -63.991 -8.006  1.00 42.30  ? 67  ILE B O   1 
ATOM   3558  C CB  . ILE B 1 67  ? 13.032  -61.667 -7.419  1.00 38.10  ? 67  ILE B CB  1 
ATOM   3559  C CG1 . ILE B 1 67  ? 14.335  -61.007 -6.975  1.00 32.71  ? 67  ILE B CG1 1 
ATOM   3560  C CG2 . ILE B 1 67  ? 11.870  -61.268 -6.523  1.00 36.79  ? 67  ILE B CG2 1 
ATOM   3561  C CD1 . ILE B 1 67  ? 14.301  -59.515 -7.082  1.00 32.41  ? 67  ILE B CD1 1 
ATOM   3562  N N   . ASP B 1 68  ? 14.068  -63.389 -9.720  1.00 42.75  ? 68  ASP B N   1 
ATOM   3563  C CA  . ASP B 1 68  ? 15.025  -63.700 -10.779 1.00 46.34  ? 68  ASP B CA  1 
ATOM   3564  C C   . ASP B 1 68  ? 16.127  -62.642 -10.781 1.00 43.69  ? 68  ASP B C   1 
ATOM   3565  O O   . ASP B 1 68  ? 15.953  -61.542 -11.315 1.00 45.27  ? 68  ASP B O   1 
ATOM   3566  C CB  . ASP B 1 68  ? 14.283  -63.783 -12.110 1.00 44.31  ? 68  ASP B CB  1 
ATOM   3567  C CG  . ASP B 1 68  ? 15.201  -63.808 -13.303 1.00 46.33  ? 68  ASP B CG  1 
ATOM   3568  O OD1 . ASP B 1 68  ? 16.373  -64.218 -13.169 1.00 47.33  ? 68  ASP B OD1 1 
ATOM   3569  O OD2 . ASP B 1 68  ? 14.726  -63.447 -14.399 1.00 50.12  ? 68  ASP B OD2 1 
ATOM   3570  N N   . GLY B 1 69  ? 17.281  -62.988 -10.193 1.00 43.88  ? 69  GLY B N   1 
ATOM   3571  C CA  . GLY B 1 69  ? 18.368  -62.030 -10.053 1.00 43.13  ? 69  GLY B CA  1 
ATOM   3572  C C   . GLY B 1 69  ? 19.021  -61.613 -11.361 1.00 48.46  ? 69  GLY B C   1 
ATOM   3573  O O   . GLY B 1 69  ? 19.645  -60.548 -11.434 1.00 48.93  ? 69  GLY B O   1 
ATOM   3574  N N   . THR B 1 70  ? 18.908  -62.440 -12.403 1.00 38.64  ? 70  THR B N   1 
ATOM   3575  C CA  . THR B 1 70  ? 19.481  -62.047 -13.685 1.00 46.90  ? 70  THR B CA  1 
ATOM   3576  C C   . THR B 1 70  ? 18.700  -60.903 -14.320 1.00 48.49  ? 70  THR B C   1 
ATOM   3577  O O   . THR B 1 70  ? 19.235  -60.208 -15.192 1.00 48.31  ? 70  THR B O   1 
ATOM   3578  C CB  . THR B 1 70  ? 19.546  -63.257 -14.628 1.00 43.64  ? 70  THR B CB  1 
ATOM   3579  O OG1 . THR B 1 70  ? 18.232  -63.600 -15.079 1.00 38.93  ? 70  THR B OG1 1 
ATOM   3580  C CG2 . THR B 1 70  ? 20.135  -64.455 -13.894 1.00 44.30  ? 70  THR B CG2 1 
ATOM   3581  N N   . SER B 1 71  ? 17.459  -60.686 -13.870 1.00 50.28  ? 71  SER B N   1 
ATOM   3582  C CA  . SER B 1 71  ? 16.606  -59.599 -14.335 1.00 48.59  ? 71  SER B CA  1 
ATOM   3583  C C   . SER B 1 71  ? 17.027  -58.245 -13.760 1.00 49.76  ? 71  SER B C   1 
ATOM   3584  O O   . SER B 1 71  ? 16.981  -57.228 -14.464 1.00 50.46  ? 71  SER B O   1 
ATOM   3585  C CB  . SER B 1 71  ? 15.159  -59.907 -13.956 1.00 46.93  ? 71  SER B CB  1 
ATOM   3586  O OG  . SER B 1 71  ? 14.255  -59.384 -14.903 1.00 53.89  ? 71  SER B OG  1 
ATOM   3587  N N   . VAL B 1 72  ? 17.440  -58.211 -12.489 1.00 51.86  ? 72  VAL B N   1 
ATOM   3588  C CA  . VAL B 1 72  ? 17.767  -56.948 -11.830 1.00 46.54  ? 72  VAL B CA  1 
ATOM   3589  C C   . VAL B 1 72  ? 19.073  -56.394 -12.390 1.00 43.06  ? 72  VAL B C   1 
ATOM   3590  O O   . VAL B 1 72  ? 20.097  -57.087 -12.430 1.00 43.54  ? 72  VAL B O   1 
ATOM   3591  C CB  . VAL B 1 72  ? 17.837  -57.140 -10.305 1.00 40.76  ? 72  VAL B CB  1 
ATOM   3592  C CG1 . VAL B 1 72  ? 18.809  -56.143 -9.664  1.00 42.71  ? 72  VAL B CG1 1 
ATOM   3593  C CG2 . VAL B 1 72  ? 16.457  -56.978 -9.705  1.00 40.12  ? 72  VAL B CG2 1 
ATOM   3594  N N   . HIS B 1 73  ? 19.037  -55.142 -12.831 1.00 40.04  ? 73  HIS B N   1 
ATOM   3595  C CA  . HIS B 1 73  ? 20.188  -54.456 -13.402 1.00 45.54  ? 73  HIS B CA  1 
ATOM   3596  C C   . HIS B 1 73  ? 20.624  -53.327 -12.477 1.00 47.05  ? 73  HIS B C   1 
ATOM   3597  O O   . HIS B 1 73  ? 19.787  -52.631 -11.890 1.00 38.10  ? 73  HIS B O   1 
ATOM   3598  C CB  . HIS B 1 73  ? 19.869  -53.887 -14.793 1.00 42.71  ? 73  HIS B CB  1 
ATOM   3599  C CG  . HIS B 1 73  ? 19.792  -54.922 -15.874 1.00 51.81  ? 73  HIS B CG  1 
ATOM   3600  N ND1 . HIS B 1 73  ? 20.641  -56.009 -15.933 1.00 54.95  ? 73  HIS B ND1 1 
ATOM   3601  C CD2 . HIS B 1 73  ? 18.955  -55.043 -16.932 1.00 54.40  ? 73  HIS B CD2 1 
ATOM   3602  C CE1 . HIS B 1 73  ? 20.331  -56.751 -16.982 1.00 61.86  ? 73  HIS B CE1 1 
ATOM   3603  N NE2 . HIS B 1 73  ? 19.311  -56.186 -17.605 1.00 59.36  ? 73  HIS B NE2 1 
ATOM   3604  N N   . VAL B 1 74  ? 21.937  -53.133 -12.381 1.00 48.56  ? 74  VAL B N   1 
ATOM   3605  C CA  . VAL B 1 74  ? 22.558  -52.175 -11.469 1.00 43.79  ? 74  VAL B CA  1 
ATOM   3606  C C   . VAL B 1 74  ? 23.384  -51.207 -12.306 1.00 45.70  ? 74  VAL B C   1 
ATOM   3607  O O   . VAL B 1 74  ? 24.366  -51.610 -12.941 1.00 48.31  ? 74  VAL B O   1 
ATOM   3608  C CB  . VAL B 1 74  ? 23.431  -52.878 -10.419 1.00 37.14  ? 74  VAL B CB  1 
ATOM   3609  C CG1 . VAL B 1 74  ? 23.930  -51.894 -9.388  1.00 44.11  ? 74  VAL B CG1 1 
ATOM   3610  C CG2 . VAL B 1 74  ? 22.653  -54.000 -9.763  1.00 32.52  ? 74  VAL B CG2 1 
ATOM   3611  N N   . GLU B 1 75  ? 22.995  -49.932 -12.308 1.00 47.65  ? 75  GLU B N   1 
ATOM   3612  C CA  . GLU B 1 75  ? 23.654  -48.901 -13.104 1.00 49.15  ? 75  GLU B CA  1 
ATOM   3613  C C   . GLU B 1 75  ? 24.451  -47.986 -12.184 1.00 50.96  ? 75  GLU B C   1 
ATOM   3614  O O   . GLU B 1 75  ? 23.871  -47.270 -11.359 1.00 51.04  ? 75  GLU B O   1 
ATOM   3615  C CB  . GLU B 1 75  ? 22.637  -48.097 -13.910 1.00 47.16  ? 75  GLU B CB  1 
ATOM   3616  C CG  . GLU B 1 75  ? 23.237  -47.378 -15.113 1.00 53.90  ? 75  GLU B CG  1 
ATOM   3617  C CD  . GLU B 1 75  ? 23.661  -48.328 -16.214 1.00 57.86  ? 75  GLU B CD  1 
ATOM   3618  O OE1 . GLU B 1 75  ? 22.780  -49.016 -16.781 1.00 57.91  ? 75  GLU B OE1 1 
ATOM   3619  O OE2 . GLU B 1 75  ? 24.874  -48.384 -16.515 1.00 62.11  ? 75  GLU B OE2 1 
ATOM   3620  N N   . ARG B 1 76  ? 25.773  -48.000 -12.336 1.00 49.38  ? 76  ARG B N   1 
ATOM   3621  C CA  . ARG B 1 76  ? 26.658  -47.265 -11.445 1.00 48.41  ? 76  ARG B CA  1 
ATOM   3622  C C   . ARG B 1 76  ? 26.978  -45.874 -11.983 1.00 56.36  ? 76  ARG B C   1 
ATOM   3623  O O   . ARG B 1 76  ? 27.061  -45.649 -13.195 1.00 54.26  ? 76  ARG B O   1 
ATOM   3624  C CB  . ARG B 1 76  ? 27.959  -48.034 -11.214 1.00 56.16  ? 76  ARG B CB  1 
ATOM   3625  C CG  . ARG B 1 76  ? 27.784  -49.370 -10.503 1.00 55.78  ? 76  ARG B CG  1 
ATOM   3626  C CD  . ARG B 1 76  ? 29.137  -49.910 -10.017 1.00 64.89  ? 76  ARG B CD  1 
ATOM   3627  N NE  . ARG B 1 76  ? 29.119  -51.293 -9.538  1.00 63.51  ? 76  ARG B NE  1 
ATOM   3628  C CZ  . ARG B 1 76  ? 28.632  -52.340 -10.199 1.00 66.20  ? 76  ARG B CZ  1 
ATOM   3629  N NH1 . ARG B 1 76  ? 28.087  -52.220 -11.400 1.00 64.89  ? 76  ARG B NH1 1 
ATOM   3630  N NH2 . ARG B 1 76  ? 28.703  -53.545 -9.642  1.00 69.19  ? 76  ARG B NH2 1 
ATOM   3631  N N   . THR B 1 77  ? 27.121  -44.934 -11.049 1.00 54.97  ? 77  THR B N   1 
ATOM   3632  C CA  . THR B 1 77  ? 27.665  -43.607 -11.293 1.00 51.57  ? 77  THR B CA  1 
ATOM   3633  C C   . THR B 1 77  ? 28.706  -43.354 -10.218 1.00 53.48  ? 77  THR B C   1 
ATOM   3634  O O   . THR B 1 77  ? 28.562  -43.818 -9.086  1.00 61.70  ? 77  THR B O   1 
ATOM   3635  C CB  . THR B 1 77  ? 26.591  -42.509 -11.230 1.00 52.90  ? 77  THR B CB  1 
ATOM   3636  O OG1 . THR B 1 77  ? 26.155  -42.349 -9.873  1.00 53.81  ? 77  THR B OG1 1 
ATOM   3637  C CG2 . THR B 1 77  ? 25.389  -42.851 -12.107 1.00 41.92  ? 77  THR B CG2 1 
ATOM   3638  N N   . GLN B 1 78  ? 29.758  -42.628 -10.560 1.00 52.69  ? 78  GLN B N   1 
ATOM   3639  C CA  . GLN B 1 78  ? 30.832  -42.458 -9.592  1.00 55.14  ? 78  GLN B CA  1 
ATOM   3640  C C   . GLN B 1 78  ? 30.644  -41.237 -8.705  1.00 58.90  ? 78  GLN B C   1 
ATOM   3641  O O   . GLN B 1 78  ? 31.507  -40.961 -7.865  1.00 63.11  ? 78  GLN B O   1 
ATOM   3642  C CB  . GLN B 1 78  ? 32.189  -42.396 -10.302 1.00 62.73  ? 78  GLN B CB  1 
ATOM   3643  C CG  . GLN B 1 78  ? 32.836  -43.765 -10.511 1.00 63.09  ? 78  GLN B CG  1 
ATOM   3644  C CD  . GLN B 1 78  ? 31.924  -44.758 -11.223 1.00 62.84  ? 78  GLN B CD  1 
ATOM   3645  O OE1 . GLN B 1 78  ? 31.767  -45.902 -10.785 1.00 63.09  ? 78  GLN B OE1 1 
ATOM   3646  N NE2 . GLN B 1 78  ? 31.329  -44.327 -12.337 1.00 62.63  ? 78  GLN B NE2 1 
ATOM   3647  N N   . THR B 1 79  ? 29.539  -40.521 -8.852  1.00 60.60  ? 79  THR B N   1 
ATOM   3648  C CA  . THR B 1 79  ? 29.227  -39.333 -8.075  1.00 58.96  ? 79  THR B CA  1 
ATOM   3649  C C   . THR B 1 79  ? 27.846  -39.478 -7.458  1.00 53.03  ? 79  THR B C   1 
ATOM   3650  O O   . THR B 1 79  ? 27.027  -40.275 -7.930  1.00 49.06  ? 79  THR B O   1 
ATOM   3651  C CB  . THR B 1 79  ? 29.280  -38.073 -8.952  1.00 52.75  ? 79  THR B CB  1 
ATOM   3652  O OG1 . THR B 1 79  ? 28.509  -38.293 -10.140 1.00 53.13  ? 79  THR B OG1 1 
ATOM   3653  C CG2 . THR B 1 79  ? 30.729  -37.730 -9.320  1.00 57.56  ? 79  THR B CG2 1 
ATOM   3654  N N   . PRO B 1 80  ? 27.560  -38.732 -6.388  1.00 50.05  ? 80  PRO B N   1 
ATOM   3655  C CA  . PRO B 1 80  ? 26.205  -38.741 -5.827  1.00 52.30  ? 80  PRO B CA  1 
ATOM   3656  C C   . PRO B 1 80  ? 25.177  -38.336 -6.870  1.00 49.66  ? 80  PRO B C   1 
ATOM   3657  O O   . PRO B 1 80  ? 25.482  -37.653 -7.849  1.00 50.40  ? 80  PRO B O   1 
ATOM   3658  C CB  . PRO B 1 80  ? 26.283  -37.719 -4.685  1.00 53.46  ? 80  PRO B CB  1 
ATOM   3659  C CG  . PRO B 1 80  ? 27.739  -37.702 -4.293  1.00 52.84  ? 80  PRO B CG  1 
ATOM   3660  C CD  . PRO B 1 80  ? 28.486  -37.914 -5.580  1.00 52.11  ? 80  PRO B CD  1 
ATOM   3661  N N   . LEU B 1 81  ? 23.935  -38.772 -6.647  1.00 45.84  ? 81  LEU B N   1 
ATOM   3662  C CA  . LEU B 1 81  ? 22.850  -38.548 -7.603  1.00 39.75  ? 81  LEU B CA  1 
ATOM   3663  C C   . LEU B 1 81  ? 22.220  -37.161 -7.421  1.00 48.37  ? 81  LEU B C   1 
ATOM   3664  O O   . LEU B 1 81  ? 21.027  -37.007 -7.135  1.00 40.20  ? 81  LEU B O   1 
ATOM   3665  C CB  . LEU B 1 81  ? 21.812  -39.655 -7.474  1.00 42.00  ? 81  LEU B CB  1 
ATOM   3666  C CG  . LEU B 1 81  ? 22.341  -41.072 -7.707  1.00 43.75  ? 81  LEU B CG  1 
ATOM   3667  C CD1 . LEU B 1 81  ? 21.188  -42.056 -7.877  1.00 42.16  ? 81  LEU B CD1 1 
ATOM   3668  C CD2 . LEU B 1 81  ? 23.272  -41.106 -8.897  1.00 41.32  ? 81  LEU B CD2 1 
ATOM   3669  N N   . SER B 1 82  ? 23.058  -36.140 -7.623  1.00 43.89  ? 82  SER B N   1 
ATOM   3670  C CA  . SER B 1 82  ? 22.655  -34.743 -7.549  1.00 41.77  ? 82  SER B CA  1 
ATOM   3671  C C   . SER B 1 82  ? 21.584  -34.414 -8.589  1.00 37.99  ? 82  SER B C   1 
ATOM   3672  O O   . SER B 1 82  ? 21.206  -35.235 -9.428  1.00 41.75  ? 82  SER B O   1 
ATOM   3673  C CB  . SER B 1 82  ? 23.853  -33.826 -7.798  1.00 40.80  ? 82  SER B CB  1 
ATOM   3674  O OG  . SER B 1 82  ? 24.164  -33.795 -9.189  1.00 36.79  ? 82  SER B OG  1 
ATOM   3675  N N   . GLU B 1 83  ? 21.114  -33.161 -8.534  1.00 40.17  ? 83  GLU B N   1 
ATOM   3676  C CA  . GLU B 1 83  ? 20.235  -32.642 -9.579  1.00 34.26  ? 83  GLU B CA  1 
ATOM   3677  C C   . GLU B 1 83  ? 20.960  -32.571 -10.916 1.00 35.05  ? 83  GLU B C   1 
ATOM   3678  O O   . GLU B 1 83  ? 20.364  -32.823 -11.972 1.00 34.55  ? 83  GLU B O   1 
ATOM   3679  C CB  . GLU B 1 83  ? 19.712  -31.257 -9.191  1.00 38.92  ? 83  GLU B CB  1 
ATOM   3680  C CG  . GLU B 1 83  ? 18.857  -31.233 -7.922  1.00 41.31  ? 83  GLU B CG  1 
ATOM   3681  C CD  . GLU B 1 83  ? 17.402  -31.608 -8.181  1.00 49.51  ? 83  GLU B CD  1 
ATOM   3682  O OE1 . GLU B 1 83  ? 16.633  -30.764 -8.714  1.00 49.12  ? 83  GLU B OE1 1 
ATOM   3683  O OE2 . GLU B 1 83  ? 17.045  -32.773 -7.891  1.00 40.44  ? 83  GLU B OE2 1 
ATOM   3684  N N   . ALA B 1 84  ? 22.248  -32.215 -10.894 1.00 32.92  ? 84  ALA B N   1 
ATOM   3685  C CA  . ALA B 1 84  ? 23.006  -32.143 -12.140 1.00 35.36  ? 84  ALA B CA  1 
ATOM   3686  C C   . ALA B 1 84  ? 23.089  -33.516 -12.798 1.00 36.26  ? 84  ALA B C   1 
ATOM   3687  O O   . ALA B 1 84  ? 22.833  -33.653 -14.001 1.00 40.74  ? 84  ALA B O   1 
ATOM   3688  C CB  . ALA B 1 84  ? 24.397  -31.561 -11.879 1.00 26.93  ? 84  ALA B CB  1 
ATOM   3689  N N   . VAL B 1 85  ? 23.365  -34.559 -12.016 1.00 35.98  ? 85  VAL B N   1 
ATOM   3690  C CA  . VAL B 1 85  ? 23.414  -35.900 -12.595 1.00 39.69  ? 85  VAL B CA  1 
ATOM   3691  C C   . VAL B 1 85  ? 22.060  -36.292 -13.178 1.00 39.72  ? 85  VAL B C   1 
ATOM   3692  O O   . VAL B 1 85  ? 21.985  -36.842 -14.283 1.00 37.92  ? 85  VAL B O   1 
ATOM   3693  C CB  . VAL B 1 85  ? 23.897  -36.924 -11.558 1.00 35.96  ? 85  VAL B CB  1 
ATOM   3694  C CG1 . VAL B 1 85  ? 23.673  -38.315 -12.080 1.00 38.60  ? 85  VAL B CG1 1 
ATOM   3695  C CG2 . VAL B 1 85  ? 25.342  -36.697 -11.255 1.00 37.86  ? 85  VAL B CG2 1 
ATOM   3696  N N   . LEU B 1 86  ? 20.965  -35.994 -12.465 1.00 38.44  ? 86  LEU B N   1 
ATOM   3697  C CA  . LEU B 1 86  ? 19.649  -36.394 -12.958 1.00 37.40  ? 86  LEU B CA  1 
ATOM   3698  C C   . LEU B 1 86  ? 19.261  -35.681 -14.243 1.00 36.23  ? 86  LEU B C   1 
ATOM   3699  O O   . LEU B 1 86  ? 18.399  -36.180 -14.979 1.00 36.18  ? 86  LEU B O   1 
ATOM   3700  C CB  . LEU B 1 86  ? 18.578  -36.148 -11.900 1.00 36.11  ? 86  LEU B CB  1 
ATOM   3701  C CG  . LEU B 1 86  ? 18.541  -37.143 -10.750 1.00 42.29  ? 86  LEU B CG  1 
ATOM   3702  C CD1 . LEU B 1 86  ? 17.176  -37.073 -10.064 1.00 39.07  ? 86  LEU B CD1 1 
ATOM   3703  C CD2 . LEU B 1 86  ? 18.861  -38.559 -11.215 1.00 35.25  ? 86  LEU B CD2 1 
ATOM   3704  N N   . GLN B 1 87  ? 19.861  -34.531 -14.526 1.00 35.95  ? 87  GLN B N   1 
ATOM   3705  C CA  . GLN B 1 87  ? 19.630  -33.819 -15.779 1.00 44.93  ? 87  GLN B CA  1 
ATOM   3706  C C   . GLN B 1 87  ? 20.847  -33.890 -16.696 1.00 49.38  ? 87  GLN B C   1 
ATOM   3707  O O   . GLN B 1 87  ? 21.079  -32.987 -17.506 1.00 52.88  ? 87  GLN B O   1 
ATOM   3708  C CB  . GLN B 1 87  ? 19.242  -32.362 -15.520 1.00 40.17  ? 87  GLN B CB  1 
ATOM   3709  C CG  . GLN B 1 87  ? 17.731  -32.175 -15.382 1.00 45.81  ? 87  GLN B CG  1 
ATOM   3710  C CD  . GLN B 1 87  ? 16.927  -33.288 -16.072 1.00 51.69  ? 87  GLN B CD  1 
ATOM   3711  O OE1 . GLN B 1 87  ? 16.886  -33.378 -17.311 1.00 54.03  ? 87  GLN B OE1 1 
ATOM   3712  N NE2 . GLN B 1 87  ? 16.323  -34.172 -15.264 1.00 41.59  ? 87  GLN B NE2 1 
ATOM   3713  N N   . ASP B 1 88  ? 21.648  -34.946 -16.546 1.00 47.79  ? 88  ASP B N   1 
ATOM   3714  C CA  . ASP B 1 88  ? 22.745  -35.227 -17.464 1.00 46.15  ? 88  ASP B CA  1 
ATOM   3715  C C   . ASP B 1 88  ? 22.223  -36.104 -18.592 1.00 45.20  ? 88  ASP B C   1 
ATOM   3716  O O   . ASP B 1 88  ? 21.765  -37.220 -18.323 1.00 46.19  ? 88  ASP B O   1 
ATOM   3717  C CB  . ASP B 1 88  ? 23.884  -35.928 -16.737 1.00 46.05  ? 88  ASP B CB  1 
ATOM   3718  C CG  . ASP B 1 88  ? 25.149  -36.007 -17.566 1.00 47.12  ? 88  ASP B CG  1 
ATOM   3719  O OD1 . ASP B 1 88  ? 25.065  -36.436 -18.735 1.00 49.70  ? 88  ASP B OD1 1 
ATOM   3720  O OD2 . ASP B 1 88  ? 26.227  -35.646 -17.046 1.00 40.32  ? 88  ASP B OD2 1 
ATOM   3721  N N   . PRO B 1 89  ? 22.265  -35.657 -19.850 1.00 43.93  ? 89  PRO B N   1 
ATOM   3722  C CA  . PRO B 1 89  ? 21.680  -36.469 -20.924 1.00 46.06  ? 89  PRO B CA  1 
ATOM   3723  C C   . PRO B 1 89  ? 22.392  -37.794 -21.120 1.00 43.82  ? 89  PRO B C   1 
ATOM   3724  O O   . PRO B 1 89  ? 21.785  -38.728 -21.652 1.00 45.28  ? 89  PRO B O   1 
ATOM   3725  C CB  . PRO B 1 89  ? 21.803  -35.569 -22.163 1.00 44.12  ? 89  PRO B CB  1 
ATOM   3726  C CG  . PRO B 1 89  ? 22.957  -34.685 -21.872 1.00 45.43  ? 89  PRO B CG  1 
ATOM   3727  C CD  . PRO B 1 89  ? 23.019  -34.503 -20.372 1.00 49.97  ? 89  PRO B CD  1 
ATOM   3728  N N   . GLU B 1 90  ? 23.646  -37.915 -20.686 1.00 45.36  ? 90  GLU B N   1 
ATOM   3729  C CA  . GLU B 1 90  ? 24.315  -39.207 -20.753 1.00 49.69  ? 90  GLU B CA  1 
ATOM   3730  C C   . GLU B 1 90  ? 23.859  -40.118 -19.623 1.00 50.06  ? 90  GLU B C   1 
ATOM   3731  O O   . GLU B 1 90  ? 23.782  -41.338 -19.808 1.00 52.16  ? 90  GLU B O   1 
ATOM   3732  C CB  . GLU B 1 90  ? 25.837  -39.020 -20.734 1.00 53.28  ? 90  GLU B CB  1 
ATOM   3733  C CG  . GLU B 1 90  ? 26.581  -39.835 -21.809 1.00 62.50  ? 90  GLU B CG  1 
ATOM   3734  C CD  . GLU B 1 90  ? 26.742  -41.311 -21.446 1.00 68.58  ? 90  GLU B CD  1 
ATOM   3735  O OE1 . GLU B 1 90  ? 27.417  -41.602 -20.432 1.00 64.72  ? 90  GLU B OE1 1 
ATOM   3736  O OE2 . GLU B 1 90  ? 26.186  -42.176 -22.167 1.00 70.16  ? 90  GLU B OE2 1 
ATOM   3737  N N   . PHE B 1 91  ? 23.530  -39.548 -18.460 1.00 47.39  ? 91  PHE B N   1 
ATOM   3738  C CA  . PHE B 1 91  ? 22.881  -40.343 -17.423 1.00 41.61  ? 91  PHE B CA  1 
ATOM   3739  C C   . PHE B 1 91  ? 21.476  -40.750 -17.847 1.00 35.86  ? 91  PHE B C   1 
ATOM   3740  O O   . PHE B 1 91  ? 21.072  -41.898 -17.646 1.00 43.18  ? 91  PHE B O   1 
ATOM   3741  C CB  . PHE B 1 91  ? 22.846  -39.579 -16.101 1.00 41.31  ? 91  PHE B CB  1 
ATOM   3742  C CG  . PHE B 1 91  ? 22.096  -40.300 -15.010 1.00 42.44  ? 91  PHE B CG  1 
ATOM   3743  C CD1 . PHE B 1 91  ? 22.709  -41.316 -14.281 1.00 38.61  ? 91  PHE B CD1 1 
ATOM   3744  C CD2 . PHE B 1 91  ? 20.779  -39.968 -14.715 1.00 39.66  ? 91  PHE B CD2 1 
ATOM   3745  C CE1 . PHE B 1 91  ? 22.026  -41.977 -13.282 1.00 35.78  ? 91  PHE B CE1 1 
ATOM   3746  C CE2 . PHE B 1 91  ? 20.091  -40.635 -13.714 1.00 34.23  ? 91  PHE B CE2 1 
ATOM   3747  C CZ  . PHE B 1 91  ? 20.719  -41.640 -13.001 1.00 36.10  ? 91  PHE B CZ  1 
ATOM   3748  N N   . ILE B 1 92  ? 20.714  -39.825 -18.432 1.00 41.72  ? 92  ILE B N   1 
ATOM   3749  C CA  . ILE B 1 92  ? 19.415  -40.182 -18.997 1.00 38.56  ? 92  ILE B CA  1 
ATOM   3750  C C   . ILE B 1 92  ? 19.574  -41.316 -20.001 1.00 42.85  ? 92  ILE B C   1 
ATOM   3751  O O   . ILE B 1 92  ? 18.795  -42.278 -20.003 1.00 45.31  ? 92  ILE B O   1 
ATOM   3752  C CB  . ILE B 1 92  ? 18.749  -38.943 -19.635 1.00 41.27  ? 92  ILE B CB  1 
ATOM   3753  C CG1 . ILE B 1 92  ? 18.718  -37.769 -18.643 1.00 44.99  ? 92  ILE B CG1 1 
ATOM   3754  C CG2 . ILE B 1 92  ? 17.342  -39.270 -20.143 1.00 37.25  ? 92  ILE B CG2 1 
ATOM   3755  C CD1 . ILE B 1 92  ? 17.686  -36.699 -18.977 1.00 45.21  ? 92  ILE B CD1 1 
ATOM   3756  N N   . ASP B 1 93  ? 20.610  -41.240 -20.847 1.00 46.29  ? 93  ASP B N   1 
ATOM   3757  C CA  . ASP B 1 93  ? 20.733  -42.178 -21.963 1.00 50.41  ? 93  ASP B CA  1 
ATOM   3758  C C   . ASP B 1 93  ? 20.979  -43.596 -21.473 1.00 46.30  ? 93  ASP B C   1 
ATOM   3759  O O   . ASP B 1 93  ? 20.381  -44.549 -21.989 1.00 49.14  ? 93  ASP B O   1 
ATOM   3760  C CB  . ASP B 1 93  ? 21.851  -41.743 -22.915 1.00 49.46  ? 93  ASP B CB  1 
ATOM   3761  C CG  . ASP B 1 93  ? 21.399  -40.675 -23.902 1.00 48.58  ? 93  ASP B CG  1 
ATOM   3762  O OD1 . ASP B 1 93  ? 20.173  -40.529 -24.122 1.00 53.16  ? 93  ASP B OD1 1 
ATOM   3763  O OD2 . ASP B 1 93  ? 22.278  -39.992 -24.468 1.00 46.73  ? 93  ASP B OD2 1 
ATOM   3764  N N   . ARG B 1 94  ? 21.856  -43.755 -20.481 1.00 42.50  ? 94  ARG B N   1 
ATOM   3765  C CA  . ARG B 1 94  ? 22.048  -45.071 -19.889 1.00 43.68  ? 94  ARG B CA  1 
ATOM   3766  C C   . ARG B 1 94  ? 20.728  -45.629 -19.369 1.00 48.16  ? 94  ARG B C   1 
ATOM   3767  O O   . ARG B 1 94  ? 20.445  -46.821 -19.525 1.00 49.69  ? 94  ARG B O   1 
ATOM   3768  C CB  . ARG B 1 94  ? 23.089  -44.990 -18.772 1.00 48.60  ? 94  ARG B CB  1 
ATOM   3769  C CG  . ARG B 1 94  ? 24.485  -44.591 -19.255 1.00 51.41  ? 94  ARG B CG  1 
ATOM   3770  C CD  . ARG B 1 94  ? 25.465  -44.470 -18.097 1.00 52.19  ? 94  ARG B CD  1 
ATOM   3771  N NE  . ARG B 1 94  ? 26.727  -43.857 -18.497 1.00 63.44  ? 94  ARG B NE  1 
ATOM   3772  C CZ  . ARG B 1 94  ? 27.756  -43.646 -17.684 1.00 62.28  ? 94  ARG B CZ  1 
ATOM   3773  N NH1 . ARG B 1 94  ? 27.721  -44.013 -16.413 1.00 58.33  ? 94  ARG B NH1 1 
ATOM   3774  N NH2 . ARG B 1 94  ? 28.847  -43.050 -18.158 1.00 67.49  ? 94  ARG B NH2 1 
ATOM   3775  N N   . LEU B 1 95  ? 19.891  -44.775 -18.778 1.00 45.32  ? 95  LEU B N   1 
ATOM   3776  C CA  . LEU B 1 95  ? 18.614  -45.247 -18.260 1.00 42.01  ? 95  LEU B CA  1 
ATOM   3777  C C   . LEU B 1 95  ? 17.660  -45.597 -19.392 1.00 42.22  ? 95  LEU B C   1 
ATOM   3778  O O   . LEU B 1 95  ? 16.860  -46.534 -19.271 1.00 43.90  ? 95  LEU B O   1 
ATOM   3779  C CB  . LEU B 1 95  ? 17.998  -44.186 -17.352 1.00 41.18  ? 95  LEU B CB  1 
ATOM   3780  C CG  . LEU B 1 95  ? 18.138  -44.300 -15.841 1.00 36.54  ? 95  LEU B CG  1 
ATOM   3781  C CD1 . LEU B 1 95  ? 19.522  -44.749 -15.424 1.00 43.67  ? 95  LEU B CD1 1 
ATOM   3782  C CD2 . LEU B 1 95  ? 17.857  -42.929 -15.301 1.00 37.48  ? 95  LEU B CD2 1 
ATOM   3783  N N   . ALA B 1 96  ? 17.724  -44.852 -20.498 1.00 42.03  ? 96  ALA B N   1 
ATOM   3784  C CA  . ALA B 1 96  ? 16.831  -45.111 -21.621 1.00 43.74  ? 96  ALA B CA  1 
ATOM   3785  C C   . ALA B 1 96  ? 17.122  -46.447 -22.292 1.00 44.87  ? 96  ALA B C   1 
ATOM   3786  O O   . ALA B 1 96  ? 16.257  -46.969 -23.006 1.00 46.41  ? 96  ALA B O   1 
ATOM   3787  C CB  . ALA B 1 96  ? 16.928  -43.975 -22.641 1.00 44.38  ? 96  ALA B CB  1 
ATOM   3788  N N   . ALA B 1 97  ? 18.315  -47.010 -22.065 1.00 44.88  ? 97  ALA B N   1 
ATOM   3789  C CA  . ALA B 1 97  ? 18.649  -48.326 -22.598 1.00 45.42  ? 97  ALA B CA  1 
ATOM   3790  C C   . ALA B 1 97  ? 17.760  -49.419 -22.019 1.00 46.17  ? 97  ALA B C   1 
ATOM   3791  O O   . ALA B 1 97  ? 17.535  -50.442 -22.673 1.00 47.24  ? 97  ALA B O   1 
ATOM   3792  C CB  . ALA B 1 97  ? 20.117  -48.646 -22.319 1.00 40.30  ? 97  ALA B CB  1 
ATOM   3793  N N   . HIS B 1 98  ? 17.254  -49.235 -20.800 1.00 42.86  ? 98  HIS B N   1 
ATOM   3794  C CA  . HIS B 1 98  ? 16.395  -50.235 -20.185 1.00 41.61  ? 98  HIS B CA  1 
ATOM   3795  C C   . HIS B 1 98  ? 14.915  -49.952 -20.380 1.00 45.77  ? 98  HIS B C   1 
ATOM   3796  O O   . HIS B 1 98  ? 14.096  -50.864 -20.224 1.00 51.73  ? 98  HIS B O   1 
ATOM   3797  C CB  . HIS B 1 98  ? 16.680  -50.324 -18.684 1.00 46.03  ? 98  HIS B CB  1 
ATOM   3798  C CG  . HIS B 1 98  ? 18.100  -50.660 -18.352 1.00 45.81  ? 98  HIS B CG  1 
ATOM   3799  N ND1 . HIS B 1 98  ? 18.578  -51.953 -18.346 1.00 48.02  ? 98  HIS B ND1 1 
ATOM   3800  C CD2 . HIS B 1 98  ? 19.143  -49.872 -18.001 1.00 50.80  ? 98  HIS B CD2 1 
ATOM   3801  C CE1 . HIS B 1 98  ? 19.855  -51.947 -18.004 1.00 49.30  ? 98  HIS B CE1 1 
ATOM   3802  N NE2 . HIS B 1 98  ? 20.223  -50.696 -17.790 1.00 54.56  ? 98  HIS B NE2 1 
ATOM   3803  N N   . THR B 1 99  ? 14.565  -48.724 -20.745 1.00 43.68  ? 99  THR B N   1 
ATOM   3804  C CA  . THR B 1 99  ? 13.205  -48.214 -20.681 1.00 45.48  ? 99  THR B CA  1 
ATOM   3805  C C   . THR B 1 99  ? 12.497  -48.209 -22.031 1.00 44.78  ? 99  THR B C   1 
ATOM   3806  O O   . THR B 1 99  ? 11.278  -48.420 -22.089 1.00 45.11  ? 99  THR B O   1 
ATOM   3807  C CB  . THR B 1 99  ? 13.255  -46.795 -20.097 1.00 49.65  ? 99  THR B CB  1 
ATOM   3808  O OG1 . THR B 1 99  ? 13.438  -46.876 -18.676 1.00 48.14  ? 99  THR B OG1 1 
ATOM   3809  C CG2 . THR B 1 99  ? 11.994  -46.000 -20.421 1.00 47.61  ? 99  THR B CG2 1 
ATOM   3810  N N   . GLY B 1 100 ? 13.235  -47.978 -23.120 1.00 47.23  ? 100 GLY B N   1 
ATOM   3811  C CA  . GLY B 1 100 ? 12.668  -47.967 -24.459 1.00 47.05  ? 100 GLY B CA  1 
ATOM   3812  C C   . GLY B 1 100 ? 11.695  -46.829 -24.701 1.00 43.12  ? 100 GLY B C   1 
ATOM   3813  O O   . GLY B 1 100 ? 12.060  -45.658 -24.572 1.00 50.11  ? 100 GLY B O   1 
ATOM   3814  N N   . THR B 1 101 ? 10.457  -47.164 -25.070 1.00 38.45  ? 101 THR B N   1 
ATOM   3815  C CA  . THR B 1 101 ? 9.391   -46.175 -25.209 1.00 47.08  ? 101 THR B CA  1 
ATOM   3816  C C   . THR B 1 101 ? 8.858   -45.666 -23.872 1.00 49.12  ? 101 THR B C   1 
ATOM   3817  O O   . THR B 1 101 ? 8.028   -44.748 -23.870 1.00 46.73  ? 101 THR B O   1 
ATOM   3818  C CB  . THR B 1 101 ? 8.208   -46.764 -25.961 1.00 48.34  ? 101 THR B CB  1 
ATOM   3819  O OG1 . THR B 1 101 ? 7.559   -47.719 -25.109 1.00 39.70  ? 101 THR B OG1 1 
ATOM   3820  C CG2 . THR B 1 101 ? 8.661   -47.441 -27.243 1.00 47.34  ? 101 THR B CG2 1 
ATOM   3821  N N   . GLY B 1 102 ? 9.266   -46.265 -22.751 1.00 49.29  ? 102 GLY B N   1 
ATOM   3822  C CA  . GLY B 1 102 ? 8.736   -45.917 -21.451 1.00 47.02  ? 102 GLY B CA  1 
ATOM   3823  C C   . GLY B 1 102 ? 7.688   -46.862 -20.894 1.00 48.12  ? 102 GLY B C   1 
ATOM   3824  O O   . GLY B 1 102 ? 7.383   -46.772 -19.693 1.00 46.81  ? 102 GLY B O   1 
ATOM   3825  N N   . ALA B 1 103 ? 7.156   -47.779 -21.707 1.00 45.10  ? 103 ALA B N   1 
ATOM   3826  C CA  . ALA B 1 103 ? 5.956   -48.523 -21.335 1.00 40.90  ? 103 ALA B CA  1 
ATOM   3827  C C   . ALA B 1 103 ? 6.222   -49.499 -20.192 1.00 43.33  ? 103 ALA B C   1 
ATOM   3828  O O   . ALA B 1 103 ? 7.193   -50.259 -20.220 1.00 45.09  ? 103 ALA B O   1 
ATOM   3829  C CB  . ALA B 1 103 ? 5.404   -49.272 -22.548 1.00 35.33  ? 103 ALA B CB  1 
ATOM   3830  N N   . GLY B 1 104 ? 5.344   -49.480 -19.186 1.00 44.48  ? 104 GLY B N   1 
ATOM   3831  C CA  . GLY B 1 104 ? 5.456   -50.353 -18.029 1.00 36.83  ? 104 GLY B CA  1 
ATOM   3832  C C   . GLY B 1 104 ? 6.567   -50.029 -17.052 1.00 39.42  ? 104 GLY B C   1 
ATOM   3833  O O   . GLY B 1 104 ? 6.891   -50.872 -16.202 1.00 36.44  ? 104 GLY B O   1 
ATOM   3834  N N   . TRP B 1 105 ? 7.164   -48.840 -17.143 1.00 34.84  ? 105 TRP B N   1 
ATOM   3835  C CA  . TRP B 1 105 ? 8.253   -48.424 -16.267 1.00 41.50  ? 105 TRP B CA  1 
ATOM   3836  C C   . TRP B 1 105 ? 7.818   -47.238 -15.411 1.00 38.13  ? 105 TRP B C   1 
ATOM   3837  O O   . TRP B 1 105 ? 7.005   -46.411 -15.831 1.00 32.40  ? 105 TRP B O   1 
ATOM   3838  C CB  . TRP B 1 105 ? 9.505   -48.041 -17.072 1.00 33.56  ? 105 TRP B CB  1 
ATOM   3839  C CG  . TRP B 1 105 ? 10.327  -49.217 -17.497 1.00 42.38  ? 105 TRP B CG  1 
ATOM   3840  C CD1 . TRP B 1 105 ? 10.102  -50.022 -18.575 1.00 41.32  ? 105 TRP B CD1 1 
ATOM   3841  C CD2 . TRP B 1 105 ? 11.516  -49.722 -16.858 1.00 40.69  ? 105 TRP B CD2 1 
ATOM   3842  N NE1 . TRP B 1 105 ? 11.071  -51.001 -18.643 1.00 41.65  ? 105 TRP B NE1 1 
ATOM   3843  C CE2 . TRP B 1 105 ? 11.948  -50.839 -17.604 1.00 39.13  ? 105 TRP B CE2 1 
ATOM   3844  C CE3 . TRP B 1 105 ? 12.248  -49.342 -15.727 1.00 39.72  ? 105 TRP B CE3 1 
ATOM   3845  C CZ2 . TRP B 1 105 ? 13.084  -51.575 -17.261 1.00 40.34  ? 105 TRP B CZ2 1 
ATOM   3846  C CZ3 . TRP B 1 105 ? 13.381  -50.082 -15.384 1.00 39.14  ? 105 TRP B CZ3 1 
ATOM   3847  C CH2 . TRP B 1 105 ? 13.784  -51.184 -16.152 1.00 40.38  ? 105 TRP B CH2 1 
ATOM   3848  N N   . SER B 1 106 ? 8.357   -47.166 -14.197 1.00 36.45  ? 106 SER B N   1 
ATOM   3849  C CA  . SER B 1 106 ? 8.136   -46.021 -13.324 1.00 33.80  ? 106 SER B CA  1 
ATOM   3850  C C   . SER B 1 106 ? 9.451   -45.661 -12.653 1.00 35.57  ? 106 SER B C   1 
ATOM   3851  O O   . SER B 1 106 ? 10.427  -46.418 -12.708 1.00 34.27  ? 106 SER B O   1 
ATOM   3852  C CB  . SER B 1 106 ? 7.065   -46.310 -12.271 1.00 30.33  ? 106 SER B CB  1 
ATOM   3853  O OG  . SER B 1 106 ? 7.609   -47.149 -11.276 1.00 36.36  ? 106 SER B OG  1 
ATOM   3854  N N   . LEU B 1 107 ? 9.471   -44.492 -12.015 1.00 30.87  ? 107 LEU B N   1 
ATOM   3855  C CA  . LEU B 1 107 ? 10.610  -44.035 -11.239 1.00 30.71  ? 107 LEU B CA  1 
ATOM   3856  C C   . LEU B 1 107 ? 10.255  -44.157 -9.760  1.00 34.25  ? 107 LEU B C   1 
ATOM   3857  O O   . LEU B 1 107 ? 9.119   -43.867 -9.358  1.00 31.62  ? 107 LEU B O   1 
ATOM   3858  C CB  . LEU B 1 107 ? 10.973  -42.589 -11.605 1.00 30.30  ? 107 LEU B CB  1 
ATOM   3859  C CG  . LEU B 1 107 ? 12.390  -42.030 -11.372 1.00 35.00  ? 107 LEU B CG  1 
ATOM   3860  C CD1 . LEU B 1 107 ? 12.443  -40.507 -11.664 1.00 32.91  ? 107 LEU B CD1 1 
ATOM   3861  C CD2 . LEU B 1 107 ? 12.949  -42.316 -9.995  1.00 38.08  ? 107 LEU B CD2 1 
ATOM   3862  N N   . PHE B 1 108 ? 11.225  -44.614 -8.958  1.00 29.01  ? 108 PHE B N   1 
ATOM   3863  C CA  . PHE B 1 108 ? 11.058  -44.870 -7.528  1.00 27.39  ? 108 PHE B CA  1 
ATOM   3864  C C   . PHE B 1 108 ? 12.070  -44.020 -6.771  1.00 30.90  ? 108 PHE B C   1 
ATOM   3865  O O   . PHE B 1 108 ? 13.062  -44.539 -6.240  1.00 26.77  ? 108 PHE B O   1 
ATOM   3866  C CB  . PHE B 1 108 ? 11.246  -46.350 -7.200  1.00 27.66  ? 108 PHE B CB  1 
ATOM   3867  C CG  . PHE B 1 108 ? 10.760  -46.741 -5.831  1.00 26.16  ? 108 PHE B CG  1 
ATOM   3868  C CD1 . PHE B 1 108 ? 9.412   -46.776 -5.546  1.00 29.70  ? 108 PHE B CD1 1 
ATOM   3869  C CD2 . PHE B 1 108 ? 11.657  -47.086 -4.836  1.00 29.09  ? 108 PHE B CD2 1 
ATOM   3870  C CE1 . PHE B 1 108 ? 8.962   -47.149 -4.289  1.00 34.89  ? 108 PHE B CE1 1 
ATOM   3871  C CE2 . PHE B 1 108 ? 11.221  -47.454 -3.572  1.00 28.07  ? 108 PHE B CE2 1 
ATOM   3872  C CZ  . PHE B 1 108 ? 9.874   -47.484 -3.295  1.00 27.17  ? 108 PHE B CZ  1 
ATOM   3873  N N   . PRO B 1 109 ? 11.855  -42.709 -6.705  1.00 29.37  ? 109 PRO B N   1 
ATOM   3874  C CA  . PRO B 1 109 ? 12.871  -41.827 -6.132  1.00 26.85  ? 109 PRO B CA  1 
ATOM   3875  C C   . PRO B 1 109 ? 12.796  -41.734 -4.617  1.00 30.50  ? 109 PRO B C   1 
ATOM   3876  O O   . PRO B 1 109 ? 11.728  -41.827 -4.014  1.00 28.92  ? 109 PRO B O   1 
ATOM   3877  C CB  . PRO B 1 109 ? 12.554  -40.467 -6.768  1.00 34.71  ? 109 PRO B CB  1 
ATOM   3878  C CG  . PRO B 1 109 ? 11.135  -40.511 -7.113  1.00 25.51  ? 109 PRO B CG  1 
ATOM   3879  C CD  . PRO B 1 109 ? 10.713  -41.964 -7.257  1.00 25.80  ? 109 PRO B CD  1 
ATOM   3880  N N   . CYS B 1 110 ? 13.967  -41.517 -4.012  1.00 29.03  ? 110 CYS B N   1 
ATOM   3881  C CA  . CYS B 1 110 ? 14.044  -41.212 -2.588  1.00 32.11  ? 110 CYS B CA  1 
ATOM   3882  C C   . CYS B 1 110 ? 13.483  -39.826 -2.285  1.00 32.29  ? 110 CYS B C   1 
ATOM   3883  O O   . CYS B 1 110 ? 12.763  -39.649 -1.297  1.00 29.43  ? 110 CYS B O   1 
ATOM   3884  C CB  . CYS B 1 110 ? 15.495  -41.309 -2.102  1.00 28.49  ? 110 CYS B CB  1 
ATOM   3885  S SG  . CYS B 1 110 ? 15.737  -40.796 -0.396  1.00 32.49  ? 110 CYS B SG  1 
ATOM   3886  N N   . VAL B 1 111 ? 13.814  -38.835 -3.114  1.00 30.14  ? 111 VAL B N   1 
ATOM   3887  C CA  . VAL B 1 111 ? 13.352  -37.458 -2.953  1.00 29.62  ? 111 VAL B CA  1 
ATOM   3888  C C   . VAL B 1 111 ? 12.724  -37.033 -4.271  1.00 32.92  ? 111 VAL B C   1 
ATOM   3889  O O   . VAL B 1 111 ? 13.424  -36.919 -5.286  1.00 28.73  ? 111 VAL B O   1 
ATOM   3890  C CB  . VAL B 1 111 ? 14.481  -36.495 -2.565  1.00 27.77  ? 111 VAL B CB  1 
ATOM   3891  C CG1 . VAL B 1 111 ? 13.906  -35.145 -2.199  1.00 27.34  ? 111 VAL B CG1 1 
ATOM   3892  C CG2 . VAL B 1 111 ? 15.289  -37.048 -1.403  1.00 31.83  ? 111 VAL B CG2 1 
ATOM   3893  N N   . SER B 1 112 ? 11.409  -36.792 -4.259  1.00 31.00  ? 112 SER B N   1 
ATOM   3894  C CA  . SER B 1 112 ? 10.708  -36.283 -5.433  1.00 31.17  ? 112 SER B CA  1 
ATOM   3895  C C   . SER B 1 112 ? 11.115  -34.841 -5.749  1.00 31.74  ? 112 SER B C   1 
ATOM   3896  O O   . SER B 1 112 ? 10.302  -33.917 -5.633  1.00 27.83  ? 112 SER B O   1 
ATOM   3897  C CB  . SER B 1 112 ? 9.192   -36.360 -5.228  1.00 28.16  ? 112 SER B CB  1 
ATOM   3898  O OG  . SER B 1 112 ? 8.704   -37.657 -5.503  1.00 39.44  ? 112 SER B OG  1 
ATOM   3899  N N   . THR B 1 113 ? 12.369  -34.642 -6.148  1.00 30.18  ? 113 THR B N   1 
ATOM   3900  C CA  . THR B 1 113 ? 12.864  -33.339 -6.555  1.00 26.38  ? 113 THR B CA  1 
ATOM   3901  C C   . THR B 1 113 ? 12.320  -32.973 -7.934  1.00 34.74  ? 113 THR B C   1 
ATOM   3902  O O   . THR B 1 113 ? 11.628  -33.760 -8.600  1.00 32.67  ? 113 THR B O   1 
ATOM   3903  C CB  . THR B 1 113 ? 14.383  -33.341 -6.601  1.00 36.57  ? 113 THR B CB  1 
ATOM   3904  O OG1 . THR B 1 113 ? 14.806  -34.221 -7.656  1.00 31.24  ? 113 THR B OG1 1 
ATOM   3905  C CG2 . THR B 1 113 ? 15.015  -33.760 -5.243  1.00 28.21  ? 113 THR B CG2 1 
ATOM   3906  N N   . ARG B 1 114 ? 12.665  -31.756 -8.373  1.00 32.64  ? 114 ARG B N   1 
ATOM   3907  C CA  . ARG B 1 114 ? 12.222  -31.270 -9.676  1.00 31.23  ? 114 ARG B CA  1 
ATOM   3908  C C   . ARG B 1 114 ? 12.873  -32.054 -10.815 1.00 36.33  ? 114 ARG B C   1 
ATOM   3909  O O   . ARG B 1 114 ? 12.215  -32.380 -11.813 1.00 34.11  ? 114 ARG B O   1 
ATOM   3910  C CB  . ARG B 1 114 ? 12.536  -29.778 -9.789  1.00 38.07  ? 114 ARG B CB  1 
ATOM   3911  C CG  . ARG B 1 114 ? 12.545  -29.188 -11.185 1.00 31.90  ? 114 ARG B CG  1 
ATOM   3912  C CD  . ARG B 1 114 ? 12.914  -27.720 -11.091 1.00 34.66  ? 114 ARG B CD  1 
ATOM   3913  N NE  . ARG B 1 114 ? 13.059  -27.084 -12.394 1.00 33.26  ? 114 ARG B NE  1 
ATOM   3914  C CZ  . ARG B 1 114 ? 12.050  -26.678 -13.152 1.00 35.40  ? 114 ARG B CZ  1 
ATOM   3915  N NH1 . ARG B 1 114 ? 10.793  -26.825 -12.767 1.00 31.10  ? 114 ARG B NH1 1 
ATOM   3916  N NH2 . ARG B 1 114 ? 12.310  -26.126 -14.337 1.00 32.52  ? 114 ARG B NH2 1 
ATOM   3917  N N   . ALA B 1 115 ? 14.166  -32.357 -10.684 1.00 34.58  ? 115 ALA B N   1 
ATOM   3918  C CA  . ALA B 1 115 ? 14.853  -33.102 -11.731 1.00 39.24  ? 115 ALA B CA  1 
ATOM   3919  C C   . ALA B 1 115 ? 14.328  -34.530 -11.815 1.00 37.79  ? 115 ALA B C   1 
ATOM   3920  O O   . ALA B 1 115 ? 14.072  -35.034 -12.913 1.00 42.11  ? 115 ALA B O   1 
ATOM   3921  C CB  . ALA B 1 115 ? 16.359  -33.066 -11.482 1.00 39.49  ? 115 ALA B CB  1 
ATOM   3922  N N   . ALA B 1 116 ? 14.125  -35.179 -10.664 1.00 33.61  ? 116 ALA B N   1 
ATOM   3923  C CA  . ALA B 1 116 ? 13.402  -36.454 -10.632 1.00 35.28  ? 116 ALA B CA  1 
ATOM   3924  C C   . ALA B 1 116 ? 12.112  -36.395 -11.441 1.00 35.87  ? 116 ALA B C   1 
ATOM   3925  O O   . ALA B 1 116 ? 11.805  -37.306 -12.216 1.00 30.88  ? 116 ALA B O   1 
ATOM   3926  C CB  . ALA B 1 116 ? 13.083  -36.845 -9.188  1.00 32.72  ? 116 ALA B CB  1 
ATOM   3927  N N   . ALA B 1 117 ? 11.320  -35.342 -11.242 1.00 35.28  ? 117 ALA B N   1 
ATOM   3928  C CA  . ALA B 1 117 ? 10.102  -35.192 -12.029 1.00 37.03  ? 117 ALA B CA  1 
ATOM   3929  C C   . ALA B 1 117 ? 10.430  -34.945 -13.496 1.00 34.87  ? 117 ALA B C   1 
ATOM   3930  O O   . ALA B 1 117 ? 9.757   -35.474 -14.386 1.00 33.83  ? 117 ALA B O   1 
ATOM   3931  C CB  . ALA B 1 117 ? 9.242   -34.053 -11.471 1.00 33.40  ? 117 ALA B CB  1 
ATOM   3932  N N   . GLN B 1 118 ? 11.465  -34.150 -13.769 1.00 34.51  ? 118 GLN B N   1 
ATOM   3933  C CA  . GLN B 1 118 ? 11.872  -33.942 -15.152 1.00 36.56  ? 118 GLN B CA  1 
ATOM   3934  C C   . GLN B 1 118 ? 12.294  -35.257 -15.798 1.00 40.93  ? 118 GLN B C   1 
ATOM   3935  O O   . GLN B 1 118 ? 11.945  -35.532 -16.952 1.00 41.44  ? 118 GLN B O   1 
ATOM   3936  C CB  . GLN B 1 118 ? 13.001  -32.922 -15.208 1.00 39.57  ? 118 GLN B CB  1 
ATOM   3937  C CG  . GLN B 1 118 ? 12.575  -31.497 -14.904 1.00 38.45  ? 118 GLN B CG  1 
ATOM   3938  C CD  . GLN B 1 118 ? 13.769  -30.563 -14.840 1.00 42.18  ? 118 GLN B CD  1 
ATOM   3939  O OE1 . GLN B 1 118 ? 14.685  -30.766 -14.041 1.00 48.82  ? 118 GLN B OE1 1 
ATOM   3940  N NE2 . GLN B 1 118 ? 13.765  -29.534 -15.672 1.00 41.12  ? 118 GLN B NE2 1 
ATOM   3941  N N   . LEU B 1 119 ? 13.012  -36.097 -15.047 1.00 39.46  ? 119 LEU B N   1 
ATOM   3942  C CA  . LEU B 1 119 ? 13.495  -37.365 -15.583 1.00 39.63  ? 119 LEU B CA  1 
ATOM   3943  C C   . LEU B 1 119 ? 12.352  -38.256 -16.044 1.00 41.74  ? 119 LEU B C   1 
ATOM   3944  O O   . LEU B 1 119 ? 12.454  -38.897 -17.096 1.00 43.34  ? 119 LEU B O   1 
ATOM   3945  C CB  . LEU B 1 119 ? 14.344  -38.082 -14.539 1.00 42.78  ? 119 LEU B CB  1 
ATOM   3946  C CG  . LEU B 1 119 ? 14.969  -39.420 -14.938 1.00 36.92  ? 119 LEU B CG  1 
ATOM   3947  C CD1 . LEU B 1 119 ? 15.837  -39.264 -16.153 1.00 38.16  ? 119 LEU B CD1 1 
ATOM   3948  C CD2 . LEU B 1 119 ? 15.797  -39.922 -13.783 1.00 37.78  ? 119 LEU B CD2 1 
ATOM   3949  N N   . THR B 1 120 ? 11.253  -38.318 -15.275 1.00 39.57  ? 120 THR B N   1 
ATOM   3950  C CA  . THR B 1 120 ? 10.110  -39.119 -15.711 1.00 33.66  ? 120 THR B CA  1 
ATOM   3951  C C   . THR B 1 120 ? 9.607   -38.664 -17.073 1.00 39.69  ? 120 THR B C   1 
ATOM   3952  O O   . THR B 1 120 ? 9.185   -39.486 -17.891 1.00 41.08  ? 120 THR B O   1 
ATOM   3953  C CB  . THR B 1 120 ? 8.955   -39.059 -14.702 1.00 38.11  ? 120 THR B CB  1 
ATOM   3954  O OG1 . THR B 1 120 ? 8.358   -37.749 -14.709 1.00 39.41  ? 120 THR B OG1 1 
ATOM   3955  C CG2 . THR B 1 120 ? 9.417   -39.408 -13.298 1.00 35.43  ? 120 THR B CG2 1 
ATOM   3956  N N   . ARG B 1 121 ? 9.619   -37.355 -17.327 1.00 37.50  ? 121 ARG B N   1 
ATOM   3957  C CA  . ARG B 1 121 ? 9.195   -36.876 -18.635 1.00 42.80  ? 121 ARG B CA  1 
ATOM   3958  C C   . ARG B 1 121 ? 10.194  -37.273 -19.713 1.00 37.89  ? 121 ARG B C   1 
ATOM   3959  O O   . ARG B 1 121 ? 9.812   -37.785 -20.769 1.00 37.73  ? 121 ARG B O   1 
ATOM   3960  C CB  . ARG B 1 121 ? 8.997   -35.358 -18.617 1.00 44.56  ? 121 ARG B CB  1 
ATOM   3961  C CG  . ARG B 1 121 ? 8.002   -34.912 -19.675 1.00 40.44  ? 121 ARG B CG  1 
ATOM   3962  C CD  . ARG B 1 121 ? 6.570   -35.123 -19.186 1.00 47.26  ? 121 ARG B CD  1 
ATOM   3963  N NE  . ARG B 1 121 ? 5.993   -33.931 -18.568 1.00 55.39  ? 121 ARG B NE  1 
ATOM   3964  C CZ  . ARG B 1 121 ? 4.783   -33.881 -18.027 1.00 51.36  ? 121 ARG B CZ  1 
ATOM   3965  N NH1 . ARG B 1 121 ? 4.040   -34.969 -17.893 1.00 55.62  ? 121 ARG B NH1 1 
ATOM   3966  N NH2 . ARG B 1 121 ? 4.305   -32.713 -17.613 1.00 47.61  ? 121 ARG B NH2 1 
ATOM   3967  N N   . LYS B 1 122 ? 11.482  -37.069 -19.453 1.00 43.42  ? 122 LYS B N   1 
ATOM   3968  C CA  . LYS B 1 122 ? 12.489  -37.309 -20.477 1.00 47.11  ? 122 LYS B CA  1 
ATOM   3969  C C   . LYS B 1 122 ? 12.754  -38.793 -20.724 1.00 51.82  ? 122 LYS B C   1 
ATOM   3970  O O   . LYS B 1 122 ? 13.470  -39.124 -21.678 1.00 53.97  ? 122 LYS B O   1 
ATOM   3971  C CB  . LYS B 1 122 ? 13.772  -36.572 -20.102 1.00 42.60  ? 122 LYS B CB  1 
ATOM   3972  C CG  . LYS B 1 122 ? 13.718  -35.101 -20.513 1.00 47.07  ? 122 LYS B CG  1 
ATOM   3973  C CD  . LYS B 1 122 ? 14.654  -34.211 -19.676 1.00 48.83  ? 122 LYS B CD  1 
ATOM   3974  C CE  . LYS B 1 122 ? 13.966  -33.531 -18.475 1.00 50.39  ? 122 LYS B CE  1 
ATOM   3975  N NZ  . LYS B 1 122 ? 12.608  -32.884 -18.710 1.00 42.43  ? 122 LYS B NZ  1 
ATOM   3976  N N   . LEU B 1 123 ? 12.193  -39.690 -19.909 1.00 45.51  ? 123 LEU B N   1 
ATOM   3977  C CA  . LEU B 1 123 ? 12.163  -41.113 -20.220 1.00 40.91  ? 123 LEU B CA  1 
ATOM   3978  C C   . LEU B 1 123 ? 10.794  -41.581 -20.671 1.00 38.80  ? 123 LEU B C   1 
ATOM   3979  O O   . LEU B 1 123 ? 10.628  -42.768 -20.962 1.00 50.19  ? 123 LEU B O   1 
ATOM   3980  C CB  . LEU B 1 123 ? 12.592  -41.945 -19.009 1.00 44.24  ? 123 LEU B CB  1 
ATOM   3981  C CG  . LEU B 1 123 ? 14.064  -41.933 -18.601 1.00 42.30  ? 123 LEU B CG  1 
ATOM   3982  C CD1 . LEU B 1 123 ? 14.285  -42.824 -17.372 1.00 34.58  ? 123 LEU B CD1 1 
ATOM   3983  C CD2 . LEU B 1 123 ? 14.948  -42.354 -19.765 1.00 40.04  ? 123 LEU B CD2 1 
ATOM   3984  N N   . ASN B 1 124 ? 9.808   -40.687 -20.719 1.00 37.49  ? 124 ASN B N   1 
ATOM   3985  C CA  . ASN B 1 124 ? 8.428   -41.059 -21.030 1.00 41.70  ? 124 ASN B CA  1 
ATOM   3986  C C   . ASN B 1 124 ? 7.913   -42.202 -20.143 1.00 46.61  ? 124 ASN B C   1 
ATOM   3987  O O   . ASN B 1 124 ? 7.005   -42.948 -20.533 1.00 48.46  ? 124 ASN B O   1 
ATOM   3988  C CB  . ASN B 1 124 ? 8.275   -41.424 -22.504 1.00 45.22  ? 124 ASN B CB  1 
ATOM   3989  C CG  . ASN B 1 124 ? 6.880   -41.157 -23.013 1.00 50.58  ? 124 ASN B CG  1 
ATOM   3990  O OD1 . ASN B 1 124 ? 6.263   -40.155 -22.656 1.00 51.90  ? 124 ASN B OD1 1 
ATOM   3991  N ND2 . ASN B 1 124 ? 6.366   -42.061 -23.840 1.00 54.66  ? 124 ASN B ND2 1 
ATOM   3992  N N   . VAL B 1 125 ? 8.469   -42.356 -18.938 1.00 42.22  ? 125 VAL B N   1 
ATOM   3993  C CA  . VAL B 1 125 ? 7.934   -43.345 -18.004 1.00 38.02  ? 125 VAL B CA  1 
ATOM   3994  C C   . VAL B 1 125 ? 6.708   -42.727 -17.354 1.00 36.81  ? 125 VAL B C   1 
ATOM   3995  O O   . VAL B 1 125 ? 6.395   -41.559 -17.606 1.00 44.63  ? 125 VAL B O   1 
ATOM   3996  C CB  . VAL B 1 125 ? 8.967   -43.779 -16.952 1.00 38.42  ? 125 VAL B CB  1 
ATOM   3997  C CG1 . VAL B 1 125 ? 10.259  -44.205 -17.621 1.00 35.61  ? 125 VAL B CG1 1 
ATOM   3998  C CG2 . VAL B 1 125 ? 9.211   -42.666 -15.951 1.00 31.98  ? 125 VAL B CG2 1 
ATOM   3999  N N   . ALA B 1 126 ? 5.999   -43.495 -16.528 1.00 41.63  ? 126 ALA B N   1 
ATOM   4000  C CA  . ALA B 1 126 ? 4.791   -42.983 -15.889 1.00 38.49  ? 126 ALA B CA  1 
ATOM   4001  C C   . ALA B 1 126 ? 5.116   -41.738 -15.083 1.00 37.30  ? 126 ALA B C   1 
ATOM   4002  O O   . ALA B 1 126 ? 6.115   -41.697 -14.362 1.00 33.53  ? 126 ALA B O   1 
ATOM   4003  C CB  . ALA B 1 126 ? 4.169   -44.046 -14.984 1.00 42.45  ? 126 ALA B CB  1 
ATOM   4004  N N   . ALA B 1 127 ? 4.274   -40.717 -15.219 1.00 44.52  ? 127 ALA B N   1 
ATOM   4005  C CA  . ALA B 1 127 ? 4.548   -39.437 -14.578 1.00 36.73  ? 127 ALA B CA  1 
ATOM   4006  C C   . ALA B 1 127 ? 4.724   -39.615 -13.075 1.00 33.85  ? 127 ALA B C   1 
ATOM   4007  O O   . ALA B 1 127 ? 3.974   -40.362 -12.427 1.00 31.91  ? 127 ALA B O   1 
ATOM   4008  C CB  . ALA B 1 127 ? 3.420   -38.441 -14.868 1.00 34.40  ? 127 ALA B CB  1 
ATOM   4009  N N   . LEU B 1 128 ? 5.749   -38.961 -12.535 1.00 30.87  ? 128 LEU B N   1 
ATOM   4010  C CA  . LEU B 1 128 ? 5.895   -38.862 -11.089 1.00 32.92  ? 128 LEU B CA  1 
ATOM   4011  C C   . LEU B 1 128 ? 4.608   -38.319 -10.488 1.00 32.12  ? 128 LEU B C   1 
ATOM   4012  O O   . LEU B 1 128 ? 4.038   -37.348 -10.985 1.00 30.48  ? 128 LEU B O   1 
ATOM   4013  C CB  . LEU B 1 128 ? 7.071   -37.959 -10.731 1.00 29.47  ? 128 LEU B CB  1 
ATOM   4014  C CG  . LEU B 1 128 ? 7.608   -37.973 -9.295  1.00 31.45  ? 128 LEU B CG  1 
ATOM   4015  C CD1 . LEU B 1 128 ? 8.542   -39.139 -9.025  1.00 31.95  ? 128 LEU B CD1 1 
ATOM   4016  C CD2 . LEU B 1 128 ? 8.318   -36.671 -9.003  1.00 32.22  ? 128 LEU B CD2 1 
ATOM   4017  N N   . ASP B 1 129 ? 4.121   -38.992 -9.454  1.00 27.97  ? 129 ASP B N   1 
ATOM   4018  C CA  . ASP B 1 129 ? 2.947   -38.510 -8.754  1.00 30.98  ? 129 ASP B CA  1 
ATOM   4019  C C   . ASP B 1 129 ? 3.284   -37.219 -8.014  1.00 26.87  ? 129 ASP B C   1 
ATOM   4020  O O   . ASP B 1 129 ? 4.345   -37.090 -7.411  1.00 30.24  ? 129 ASP B O   1 
ATOM   4021  C CB  . ASP B 1 129 ? 2.439   -39.581 -7.790  1.00 28.94  ? 129 ASP B CB  1 
ATOM   4022  C CG  . ASP B 1 129 ? 0.973   -39.437 -7.502  1.00 31.58  ? 129 ASP B CG  1 
ATOM   4023  O OD1 . ASP B 1 129 ? 0.323   -38.665 -8.243  1.00 30.43  ? 129 ASP B OD1 1 
ATOM   4024  O OD2 . ASP B 1 129 ? 0.480   -40.085 -6.541  1.00 32.27  ? 129 ASP B OD2 1 
ATOM   4025  N N   . GLY B 1 130 ? 2.386   -36.247 -8.071  1.00 31.63  ? 130 GLY B N   1 
ATOM   4026  C CA  . GLY B 1 130 ? 2.734   -34.945 -7.544  1.00 26.56  ? 130 GLY B CA  1 
ATOM   4027  C C   . GLY B 1 130 ? 3.711   -34.213 -8.429  1.00 27.94  ? 130 GLY B C   1 
ATOM   4028  O O   . GLY B 1 130 ? 4.554   -33.468 -7.929  1.00 24.12  ? 130 GLY B O   1 
ATOM   4029  N N   . TYR B 1 131 ? 3.596   -34.394 -9.749  1.00 30.58  ? 131 TYR B N   1 
ATOM   4030  C CA  . TYR B 1 131 ? 4.551   -33.823 -10.700 1.00 33.18  ? 131 TYR B CA  1 
ATOM   4031  C C   . TYR B 1 131 ? 4.702   -32.316 -10.531 1.00 29.80  ? 131 TYR B C   1 
ATOM   4032  O O   . TYR B 1 131 ? 5.815   -31.809 -10.355 1.00 30.59  ? 131 TYR B O   1 
ATOM   4033  C CB  . TYR B 1 131 ? 4.113   -34.148 -12.137 1.00 34.36  ? 131 TYR B CB  1 
ATOM   4034  C CG  . TYR B 1 131 ? 5.010   -33.562 -13.210 1.00 34.38  ? 131 TYR B CG  1 
ATOM   4035  C CD1 . TYR B 1 131 ? 6.153   -34.232 -13.633 1.00 39.12  ? 131 TYR B CD1 1 
ATOM   4036  C CD2 . TYR B 1 131 ? 4.719   -32.335 -13.790 1.00 38.12  ? 131 TYR B CD2 1 
ATOM   4037  C CE1 . TYR B 1 131 ? 6.978   -33.693 -14.613 1.00 39.75  ? 131 TYR B CE1 1 
ATOM   4038  C CE2 . TYR B 1 131 ? 5.535   -31.788 -14.761 1.00 36.15  ? 131 TYR B CE2 1 
ATOM   4039  C CZ  . TYR B 1 131 ? 6.660   -32.472 -15.171 1.00 40.56  ? 131 TYR B CZ  1 
ATOM   4040  O OH  . TYR B 1 131 ? 7.466   -31.931 -16.143 1.00 43.69  ? 131 TYR B OH  1 
ATOM   4041  N N   . GLU B 1 132 ? 3.590   -31.579 -10.622 1.00 29.51  ? 132 GLU B N   1 
ATOM   4042  C CA  . GLU B 1 132 ? 3.672   -30.122 -10.639 1.00 27.99  ? 132 GLU B CA  1 
ATOM   4043  C C   . GLU B 1 132 ? 4.238   -29.584 -9.336  1.00 27.98  ? 132 GLU B C   1 
ATOM   4044  O O   . GLU B 1 132 ? 4.978   -28.590 -9.339  1.00 23.87  ? 132 GLU B O   1 
ATOM   4045  C CB  . GLU B 1 132 ? 2.296   -29.523 -10.898 1.00 25.55  ? 132 GLU B CB  1 
ATOM   4046  C CG  . GLU B 1 132 ? 1.680   -29.850 -12.254 1.00 29.95  ? 132 GLU B CG  1 
ATOM   4047  C CD  . GLU B 1 132 ? 2.452   -29.262 -13.437 1.00 41.78  ? 132 GLU B CD  1 
ATOM   4048  O OE1 . GLU B 1 132 ? 3.454   -28.535 -13.220 1.00 32.11  ? 132 GLU B OE1 1 
ATOM   4049  O OE2 . GLU B 1 132 ? 2.038   -29.535 -14.595 1.00 40.94  ? 132 GLU B OE2 1 
ATOM   4050  N N   . PHE B 1 133 ? 3.901   -30.233 -8.221  1.00 24.79  ? 133 PHE B N   1 
ATOM   4051  C CA  . PHE B 1 133 ? 4.470   -29.856 -6.928  1.00 23.78  ? 133 PHE B CA  1 
ATOM   4052  C C   . PHE B 1 133 ? 5.978   -30.084 -6.909  1.00 24.46  ? 133 PHE B C   1 
ATOM   4053  O O   . PHE B 1 133 ? 6.738   -29.229 -6.434  1.00 24.54  ? 133 PHE B O   1 
ATOM   4054  C CB  . PHE B 1 133 ? 3.760   -30.648 -5.820  1.00 23.78  ? 133 PHE B CB  1 
ATOM   4055  C CG  . PHE B 1 133 ? 4.143   -30.256 -4.414  1.00 26.45  ? 133 PHE B CG  1 
ATOM   4056  C CD1 . PHE B 1 133 ? 3.736   -29.036 -3.877  1.00 22.49  ? 133 PHE B CD1 1 
ATOM   4057  C CD2 . PHE B 1 133 ? 4.849   -31.139 -3.608  1.00 20.30  ? 133 PHE B CD2 1 
ATOM   4058  C CE1 . PHE B 1 133 ? 4.058   -28.690 -2.584  1.00 21.56  ? 133 PHE B CE1 1 
ATOM   4059  C CE2 . PHE B 1 133 ? 5.185   -30.804 -2.317  1.00 18.52  ? 133 PHE B CE2 1 
ATOM   4060  C CZ  . PHE B 1 133 ? 4.793   -29.578 -1.796  1.00 20.65  ? 133 PHE B CZ  1 
ATOM   4061  N N   . ALA B 1 134 ? 6.439   -31.217 -7.447  1.00 26.97  ? 134 ALA B N   1 
ATOM   4062  C CA  . ALA B 1 134 ? 7.878   -31.477 -7.468  1.00 24.78  ? 134 ALA B CA  1 
ATOM   4063  C C   . ALA B 1 134 ? 8.603   -30.458 -8.345  1.00 28.34  ? 134 ALA B C   1 
ATOM   4064  O O   . ALA B 1 134 ? 9.691   -29.981 -7.999  1.00 26.69  ? 134 ALA B O   1 
ATOM   4065  C CB  . ALA B 1 134 ? 8.142   -32.901 -7.964  1.00 28.65  ? 134 ALA B CB  1 
ATOM   4066  N N   . MET B 1 135 ? 7.993   -30.095 -9.474  1.00 26.45  ? 135 MET B N   1 
ATOM   4067  C CA  . MET B 1 135 ? 8.610   -29.160 -10.407 1.00 34.07  ? 135 MET B CA  1 
ATOM   4068  C C   . MET B 1 135 ? 8.809   -27.781 -9.787  1.00 34.49  ? 135 MET B C   1 
ATOM   4069  O O   . MET B 1 135 ? 9.689   -27.027 -10.222 1.00 33.14  ? 135 MET B O   1 
ATOM   4070  C CB  . MET B 1 135 ? 7.749   -29.051 -11.663 1.00 27.65  ? 135 MET B CB  1 
ATOM   4071  C CG  . MET B 1 135 ? 7.783   -30.318 -12.539 1.00 32.90  ? 135 MET B CG  1 
ATOM   4072  S SD  . MET B 1 135 ? 9.387   -30.498 -13.348 1.00 38.11  ? 135 MET B SD  1 
ATOM   4073  C CE  . MET B 1 135 ? 9.126   -29.373 -14.723 1.00 23.53  ? 135 MET B CE  1 
ATOM   4074  N N   . GLN B 1 136 ? 7.988   -27.416 -8.803  1.00 27.47  ? 136 GLN B N   1 
ATOM   4075  C CA  . GLN B 1 136 ? 8.195   -26.185 -8.051  1.00 29.71  ? 136 GLN B CA  1 
ATOM   4076  C C   . GLN B 1 136 ? 9.093   -26.412 -6.850  1.00 29.58  ? 136 GLN B C   1 
ATOM   4077  O O   . GLN B 1 136 ? 9.287   -25.498 -6.049  1.00 29.80  ? 136 GLN B O   1 
ATOM   4078  C CB  . GLN B 1 136 ? 6.851   -25.595 -7.606  1.00 23.64  ? 136 GLN B CB  1 
ATOM   4079  C CG  . GLN B 1 136 ? 5.951   -25.210 -8.786  1.00 24.85  ? 136 GLN B CG  1 
ATOM   4080  C CD  . GLN B 1 136 ? 6.610   -24.200 -9.725  1.00 24.50  ? 136 GLN B CD  1 
ATOM   4081  O OE1 . GLN B 1 136 ? 7.090   -23.149 -9.288  1.00 25.46  ? 136 GLN B OE1 1 
ATOM   4082  N NE2 . GLN B 1 136 ? 6.665   -24.529 -11.012 1.00 22.81  ? 136 GLN B NE2 1 
ATOM   4083  N N   . ASN B 1 137 ? 9.648   -27.613 -6.725  1.00 28.87  ? 137 ASN B N   1 
ATOM   4084  C CA  . ASN B 1 137 ? 10.499  -27.992 -5.600  1.00 33.79  ? 137 ASN B CA  1 
ATOM   4085  C C   . ASN B 1 137 ? 9.759   -27.829 -4.273  1.00 30.57  ? 137 ASN B C   1 
ATOM   4086  O O   . ASN B 1 137 ? 10.322  -27.379 -3.268  1.00 28.96  ? 137 ASN B O   1 
ATOM   4087  C CB  . ASN B 1 137 ? 11.825  -27.226 -5.620  1.00 37.31  ? 137 ASN B CB  1 
ATOM   4088  C CG  . ASN B 1 137 ? 12.781  -27.764 -6.680  1.00 37.58  ? 137 ASN B CG  1 
ATOM   4089  O OD1 . ASN B 1 137 ? 13.048  -28.973 -6.751  1.00 38.71  ? 137 ASN B OD1 1 
ATOM   4090  N ND2 . ASN B 1 137 ? 13.315  -26.872 -7.489  1.00 37.68  ? 137 ASN B ND2 1 
ATOM   4091  N N   . GLY B 1 138 ? 8.487   -28.244 -4.281  1.00 27.74  ? 138 GLY B N   1 
ATOM   4092  C CA  . GLY B 1 138 ? 7.684   -28.231 -3.076  1.00 25.53  ? 138 GLY B CA  1 
ATOM   4093  C C   . GLY B 1 138 ? 8.248   -29.086 -1.960  1.00 25.02  ? 138 GLY B C   1 
ATOM   4094  O O   . GLY B 1 138 ? 8.102   -28.744 -0.790  1.00 23.60  ? 138 GLY B O   1 
ATOM   4095  N N   . ILE B 1 139 ? 8.915   -30.193 -2.304  1.00 28.85  ? 139 ILE B N   1 
ATOM   4096  C CA  . ILE B 1 139 ? 9.529   -31.036 -1.285  1.00 26.35  ? 139 ILE B CA  1 
ATOM   4097  C C   . ILE B 1 139 ? 10.557  -30.254 -0.478  1.00 30.47  ? 139 ILE B C   1 
ATOM   4098  O O   . ILE B 1 139 ? 10.665  -30.416 0.746   1.00 26.29  ? 139 ILE B O   1 
ATOM   4099  C CB  . ILE B 1 139 ? 10.144  -32.289 -1.927  1.00 33.25  ? 139 ILE B CB  1 
ATOM   4100  C CG1 . ILE B 1 139 ? 9.050   -33.327 -2.203  1.00 24.81  ? 139 ILE B CG1 1 
ATOM   4101  C CG2 . ILE B 1 139 ? 11.204  -32.882 -0.992  1.00 29.93  ? 139 ILE B CG2 1 
ATOM   4102  C CD1 . ILE B 1 139 ? 8.274   -33.143 -3.488  1.00 27.72  ? 139 ILE B CD1 1 
ATOM   4103  N N   . ASP B 1 140 ? 11.316  -29.382 -1.138  1.00 32.04  ? 140 ASP B N   1 
ATOM   4104  C CA  . ASP B 1 140 ? 12.223  -28.508 -0.406  1.00 31.91  ? 140 ASP B CA  1 
ATOM   4105  C C   . ASP B 1 140 ? 11.486  -27.694 0.657   1.00 33.60  ? 140 ASP B C   1 
ATOM   4106  O O   . ASP B 1 140 ? 12.042  -27.427 1.726   1.00 32.13  ? 140 ASP B O   1 
ATOM   4107  C CB  . ASP B 1 140 ? 12.945  -27.577 -1.376  1.00 32.70  ? 140 ASP B CB  1 
ATOM   4108  C CG  . ASP B 1 140 ? 14.259  -28.153 -1.890  1.00 37.97  ? 140 ASP B CG  1 
ATOM   4109  O OD1 . ASP B 1 140 ? 14.753  -29.170 -1.346  1.00 44.90  ? 140 ASP B OD1 1 
ATOM   4110  O OD2 . ASP B 1 140 ? 14.820  -27.555 -2.839  1.00 46.46  ? 140 ASP B OD2 1 
ATOM   4111  N N   . LEU B 1 141 ? 10.233  -27.302 0.390   1.00 35.22  ? 141 LEU B N   1 
ATOM   4112  C CA  . LEU B 1 141 ? 9.483   -26.499 1.357   1.00 29.70  ? 141 LEU B CA  1 
ATOM   4113  C C   . LEU B 1 141 ? 9.076   -27.326 2.573   1.00 28.51  ? 141 LEU B C   1 
ATOM   4114  O O   . LEU B 1 141 ? 9.189   -26.858 3.712   1.00 24.24  ? 141 LEU B O   1 
ATOM   4115  C CB  . LEU B 1 141 ? 8.252   -25.878 0.691   1.00 29.31  ? 141 LEU B CB  1 
ATOM   4116  C CG  . LEU B 1 141 ? 7.069   -25.440 1.569   1.00 25.64  ? 141 LEU B CG  1 
ATOM   4117  C CD1 . LEU B 1 141 ? 7.430   -24.265 2.435   1.00 29.20  ? 141 LEU B CD1 1 
ATOM   4118  C CD2 . LEU B 1 141 ? 5.893   -25.098 0.711   1.00 27.25  ? 141 LEU B CD2 1 
ATOM   4119  N N   . LEU B 1 142 ? 8.620   -28.563 2.360   1.00 29.31  ? 142 LEU B N   1 
ATOM   4120  C CA  . LEU B 1 142 ? 8.195   -29.383 3.494   1.00 27.04  ? 142 LEU B CA  1 
ATOM   4121  C C   . LEU B 1 142 ? 9.363   -29.894 4.321   1.00 26.75  ? 142 LEU B C   1 
ATOM   4122  O O   . LEU B 1 142 ? 9.182   -30.229 5.492   1.00 30.69  ? 142 LEU B O   1 
ATOM   4123  C CB  . LEU B 1 142 ? 7.380   -30.571 3.004   1.00 23.34  ? 142 LEU B CB  1 
ATOM   4124  C CG  . LEU B 1 142 ? 6.211   -30.211 2.086   1.00 23.24  ? 142 LEU B CG  1 
ATOM   4125  C CD1 . LEU B 1 142 ? 5.531   -31.483 1.605   1.00 21.27  ? 142 LEU B CD1 1 
ATOM   4126  C CD2 . LEU B 1 142 ? 5.239   -29.283 2.812   1.00 20.47  ? 142 LEU B CD2 1 
ATOM   4127  N N   . ASN B 1 143 ? 10.554  -29.980 3.751   1.00 22.84  ? 143 ASN B N   1 
ATOM   4128  C CA  . ASN B 1 143 ? 11.680  -30.562 4.459   1.00 23.56  ? 143 ASN B CA  1 
ATOM   4129  C C   . ASN B 1 143 ? 12.477  -29.533 5.265   1.00 29.10  ? 143 ASN B C   1 
ATOM   4130  O O   . ASN B 1 143 ? 13.661  -29.753 5.516   1.00 29.36  ? 143 ASN B O   1 
ATOM   4131  C CB  . ASN B 1 143 ? 12.576  -31.300 3.463   1.00 29.95  ? 143 ASN B CB  1 
ATOM   4132  C CG  . ASN B 1 143 ? 12.099  -32.714 3.208   1.00 26.10  ? 143 ASN B CG  1 
ATOM   4133  O OD1 . ASN B 1 143 ? 11.394  -33.284 4.032   1.00 33.51  ? 143 ASN B OD1 1 
ATOM   4134  N ND2 . ASN B 1 143 ? 12.478  -33.290 2.069   1.00 30.16  ? 143 ASN B ND2 1 
ATOM   4135  N N   . MET B 1 144 ? 11.856  -28.410 5.642   1.00 30.92  ? 144 MET B N   1 
ATOM   4136  C CA  . MET B 1 144 ? 12.426  -27.419 6.551   1.00 28.59  ? 144 MET B CA  1 
ATOM   4137  C C   . MET B 1 144 ? 11.725  -27.479 7.901   1.00 26.29  ? 144 MET B C   1 
ATOM   4138  O O   . MET B 1 144 ? 10.490  -27.525 7.973   1.00 22.82  ? 144 MET B O   1 
ATOM   4139  C CB  . MET B 1 144 ? 12.322  -26.002 5.986   1.00 27.14  ? 144 MET B CB  1 
ATOM   4140  C CG  . MET B 1 144 ? 12.732  -25.869 4.531   1.00 29.74  ? 144 MET B CG  1 
ATOM   4141  S SD  . MET B 1 144 ? 12.066  -24.338 3.871   1.00 38.33  ? 144 MET B SD  1 
ATOM   4142  C CE  . MET B 1 144 ? 13.118  -23.139 4.670   1.00 23.53  ? 144 MET B CE  1 
ATOM   4143  N N   . LYS B 1 145 ? 12.518  -27.479 8.969   1.00 24.66  ? 145 LYS B N   1 
ATOM   4144  C CA  . LYS B 1 145 ? 11.938  -27.520 10.301  1.00 29.80  ? 145 LYS B CA  1 
ATOM   4145  C C   . LYS B 1 145 ? 11.086  -26.285 10.581  1.00 25.28  ? 145 LYS B C   1 
ATOM   4146  O O   . LYS B 1 145 ? 10.079  -26.382 11.298  1.00 23.57  ? 145 LYS B O   1 
ATOM   4147  C CB  . LYS B 1 145 ? 13.042  -27.684 11.346  1.00 31.89  ? 145 LYS B CB  1 
ATOM   4148  C CG  . LYS B 1 145 ? 13.968  -28.859 11.032  1.00 29.79  ? 145 LYS B CG  1 
ATOM   4149  C CD  . LYS B 1 145 ? 14.833  -29.202 12.226  1.00 34.55  ? 145 LYS B CD  1 
ATOM   4150  C CE  . LYS B 1 145 ? 15.800  -30.321 11.888  1.00 32.68  ? 145 LYS B CE  1 
ATOM   4151  N NZ  . LYS B 1 145 ? 16.897  -29.769 11.085  1.00 37.36  ? 145 LYS B NZ  1 
ATOM   4152  N N   . SER B 1 146 ? 11.452  -25.128 10.020  1.00 18.93  ? 146 SER B N   1 
ATOM   4153  C CA  . SER B 1 146 ? 10.606  -23.951 10.208  1.00 26.21  ? 146 SER B CA  1 
ATOM   4154  C C   . SER B 1 146 ? 9.198   -24.217 9.673   1.00 27.24  ? 146 SER B C   1 
ATOM   4155  O O   . SER B 1 146 ? 8.195   -23.931 10.347  1.00 24.26  ? 146 SER B O   1 
ATOM   4156  C CB  . SER B 1 146 ? 11.229  -22.730 9.524   1.00 25.44  ? 146 SER B CB  1 
ATOM   4157  O OG  . SER B 1 146 ? 11.402  -22.958 8.122   1.00 27.69  ? 146 SER B OG  1 
ATOM   4158  N N   . THR B 1 147 ? 9.112   -24.805 8.477   1.00 21.82  ? 147 THR B N   1 
ATOM   4159  C CA  . THR B 1 147 ? 7.823   -25.135 7.888   1.00 20.65  ? 147 THR B CA  1 
ATOM   4160  C C   . THR B 1 147 ? 7.031   -26.052 8.801   1.00 22.10  ? 147 THR B C   1 
ATOM   4161  O O   . THR B 1 147 ? 5.812   -25.897 8.946   1.00 20.72  ? 147 THR B O   1 
ATOM   4162  C CB  . THR B 1 147 ? 8.015   -25.790 6.515   1.00 21.22  ? 147 THR B CB  1 
ATOM   4163  O OG1 . THR B 1 147 ? 8.676   -24.871 5.634   1.00 24.38  ? 147 THR B OG1 1 
ATOM   4164  C CG2 . THR B 1 147 ? 6.664   -26.191 5.911   1.00 21.03  ? 147 THR B CG2 1 
ATOM   4165  N N   . PHE B 1 148 ? 7.697   -27.014 9.430   1.00 21.23  ? 148 PHE B N   1 
ATOM   4166  C CA  . PHE B 1 148 ? 6.950   -27.932 10.277  1.00 22.92  ? 148 PHE B CA  1 
ATOM   4167  C C   . PHE B 1 148 ? 6.353   -27.216 11.487  1.00 25.54  ? 148 PHE B C   1 
ATOM   4168  O O   . PHE B 1 148 ? 5.190   -27.444 11.827  1.00 21.65  ? 148 PHE B O   1 
ATOM   4169  C CB  . PHE B 1 148 ? 7.825   -29.079 10.742  1.00 20.08  ? 148 PHE B CB  1 
ATOM   4170  C CG  . PHE B 1 148 ? 7.135   -29.955 11.715  1.00 23.78  ? 148 PHE B CG  1 
ATOM   4171  C CD1 . PHE B 1 148 ? 6.198   -30.887 11.281  1.00 24.31  ? 148 PHE B CD1 1 
ATOM   4172  C CD2 . PHE B 1 148 ? 7.376   -29.823 13.076  1.00 22.44  ? 148 PHE B CD2 1 
ATOM   4173  C CE1 . PHE B 1 148 ? 5.525   -31.689 12.194  1.00 22.84  ? 148 PHE B CE1 1 
ATOM   4174  C CE2 . PHE B 1 148 ? 6.720   -30.623 13.987  1.00 22.95  ? 148 PHE B CE2 1 
ATOM   4175  C CZ  . PHE B 1 148 ? 5.789   -31.557 13.550  1.00 21.63  ? 148 PHE B CZ  1 
ATOM   4176  N N   . ARG B 1 149 ? 7.141   -26.359 12.150  1.00 22.38  ? 149 ARG B N   1 
ATOM   4177  C CA  . ARG B 1 149 ? 6.638   -25.579 13.281  1.00 19.97  ? 149 ARG B CA  1 
ATOM   4178  C C   . ARG B 1 149 ? 5.427   -24.740 12.880  1.00 22.44  ? 149 ARG B C   1 
ATOM   4179  O O   . ARG B 1 149 ? 4.425   -24.681 13.611  1.00 23.22  ? 149 ARG B O   1 
ATOM   4180  C CB  . ARG B 1 149 ? 7.761   -24.686 13.826  1.00 18.87  ? 149 ARG B CB  1 
ATOM   4181  C CG  . ARG B 1 149 ? 8.873   -25.497 14.587  1.00 24.69  ? 149 ARG B CG  1 
ATOM   4182  C CD  . ARG B 1 149 ? 9.552   -24.692 15.717  1.00 26.55  ? 149 ARG B CD  1 
ATOM   4183  N NE  . ARG B 1 149 ? 8.592   -24.233 16.721  1.00 29.88  ? 149 ARG B NE  1 
ATOM   4184  C CZ  . ARG B 1 149 ? 8.211   -24.920 17.795  1.00 29.04  ? 149 ARG B CZ  1 
ATOM   4185  N NH1 . ARG B 1 149 ? 8.748   -26.096 18.101  1.00 25.42  ? 149 ARG B NH1 1 
ATOM   4186  N NH2 . ARG B 1 149 ? 7.281   -24.404 18.594  1.00 24.78  ? 149 ARG B NH2 1 
ATOM   4187  N N   . ARG B 1 150 ? 5.495   -24.101 11.710  1.00 22.76  ? 150 ARG B N   1 
ATOM   4188  C CA  . ARG B 1 150 ? 4.419   -23.232 11.257  1.00 22.40  ? 150 ARG B CA  1 
ATOM   4189  C C   . ARG B 1 150 ? 3.160   -24.029 10.936  1.00 21.61  ? 150 ARG B C   1 
ATOM   4190  O O   . ARG B 1 150 ? 2.069   -23.677 11.390  1.00 24.09  ? 150 ARG B O   1 
ATOM   4191  C CB  . ARG B 1 150 ? 4.879   -22.432 10.040  1.00 20.78  ? 150 ARG B CB  1 
ATOM   4192  C CG  . ARG B 1 150 ? 6.024   -21.496 10.352  1.00 18.66  ? 150 ARG B CG  1 
ATOM   4193  C CD  . ARG B 1 150 ? 6.797   -21.074 9.103   1.00 19.16  ? 150 ARG B CD  1 
ATOM   4194  N NE  . ARG B 1 150 ? 7.555   -19.864 9.390   1.00 23.30  ? 150 ARG B NE  1 
ATOM   4195  C CZ  . ARG B 1 150 ? 8.356   -19.229 8.542   1.00 22.47  ? 150 ARG B CZ  1 
ATOM   4196  N NH1 . ARG B 1 150 ? 8.646   -19.725 7.352   1.00 25.20  ? 150 ARG B NH1 1 
ATOM   4197  N NH2 . ARG B 1 150 ? 8.877   -18.064 8.902   1.00 24.59  ? 150 ARG B NH2 1 
ATOM   4198  N N   . LEU B 1 151 ? 3.277   -25.090 10.137  1.00 20.08  ? 151 LEU B N   1 
ATOM   4199  C CA  . LEU B 1 151 ? 2.097   -25.898 9.828   1.00 24.60  ? 151 LEU B CA  1 
ATOM   4200  C C   . LEU B 1 151 ? 1.556   -26.568 11.080  1.00 26.38  ? 151 LEU B C   1 
ATOM   4201  O O   . LEU B 1 151 ? 0.330   -26.696 11.258  1.00 19.14  ? 151 LEU B O   1 
ATOM   4202  C CB  . LEU B 1 151 ? 2.422   -26.961 8.770   1.00 21.87  ? 151 LEU B CB  1 
ATOM   4203  C CG  . LEU B 1 151 ? 2.825   -26.453 7.377   1.00 25.53  ? 151 LEU B CG  1 
ATOM   4204  C CD1 . LEU B 1 151 ? 3.297   -27.591 6.498   1.00 23.76  ? 151 LEU B CD1 1 
ATOM   4205  C CD2 . LEU B 1 151 ? 1.644   -25.793 6.728   1.00 25.39  ? 151 LEU B CD2 1 
ATOM   4206  N N   . ALA B 1 152 ? 2.461   -27.012 11.957  1.00 22.22  ? 152 ALA B N   1 
ATOM   4207  C CA  . ALA B 1 152 ? 2.031   -27.703 13.160  1.00 22.85  ? 152 ALA B CA  1 
ATOM   4208  C C   . ALA B 1 152 ? 1.247   -26.750 14.051  1.00 22.77  ? 152 ALA B C   1 
ATOM   4209  O O   . ALA B 1 152 ? 0.099   -27.022 14.413  1.00 21.83  ? 152 ALA B O   1 
ATOM   4210  C CB  . ALA B 1 152 ? 3.236   -28.297 13.886  1.00 15.63  ? 152 ALA B CB  1 
ATOM   4211  N N   . ALA B 1 153 ? 1.850   -25.617 14.399  1.00 21.54  ? 153 ALA B N   1 
ATOM   4212  C CA  . ALA B 1 153 ? 1.071   -24.544 14.987  1.00 23.15  ? 153 ALA B CA  1 
ATOM   4213  C C   . ALA B 1 153 ? -0.010  -24.164 13.991  1.00 24.64  ? 153 ALA B C   1 
ATOM   4214  O O   . ALA B 1 153 ? 0.133   -24.365 12.788  1.00 32.19  ? 153 ALA B O   1 
ATOM   4215  C CB  . ALA B 1 153 ? 1.962   -23.353 15.320  1.00 17.97  ? 153 ALA B CB  1 
ATOM   4216  N N   . GLY B 1 154 ? -1.115  -23.679 14.457  1.00 24.22  ? 154 GLY B N   1 
ATOM   4217  C CA  . GLY B 1 154 ? -2.034  -23.387 13.336  1.00 31.97  ? 154 GLY B CA  1 
ATOM   4218  C C   . GLY B 1 154 ? -2.885  -24.536 12.829  1.00 21.21  ? 154 GLY B C   1 
ATOM   4219  O O   . GLY B 1 154 ? -4.085  -24.382 12.665  1.00 26.32  ? 154 GLY B O   1 
ATOM   4220  N N   . LEU B 1 155 ? -2.303  -25.712 12.612  1.00 22.31  ? 155 LEU B N   1 
ATOM   4221  C CA  . LEU B 1 155 ? -3.202  -26.854 12.509  1.00 20.96  ? 155 LEU B CA  1 
ATOM   4222  C C   . LEU B 1 155 ? -3.626  -27.329 13.889  1.00 23.42  ? 155 LEU B C   1 
ATOM   4223  O O   . LEU B 1 155 ? -4.720  -27.883 14.031  1.00 25.08  ? 155 LEU B O   1 
ATOM   4224  C CB  . LEU B 1 155 ? -2.568  -28.006 11.704  1.00 21.99  ? 155 LEU B CB  1 
ATOM   4225  C CG  . LEU B 1 155 ? -3.419  -29.275 11.516  1.00 28.62  ? 155 LEU B CG  1 
ATOM   4226  C CD1 . LEU B 1 155 ? -4.783  -28.974 10.860  1.00 26.47  ? 155 LEU B CD1 1 
ATOM   4227  C CD2 . LEU B 1 155 ? -2.679  -30.350 10.741  1.00 22.42  ? 155 LEU B CD2 1 
ATOM   4228  N N   . GLY B 1 156 ? -2.796  -27.096 14.910  1.00 22.68  ? 156 GLY B N   1 
ATOM   4229  C CA  . GLY B 1 156 ? -3.081  -27.535 16.261  1.00 26.24  ? 156 GLY B CA  1 
ATOM   4230  C C   . GLY B 1 156 ? -2.328  -28.773 16.705  1.00 28.26  ? 156 GLY B C   1 
ATOM   4231  O O   . GLY B 1 156 ? -2.601  -29.292 17.804  1.00 28.38  ? 156 GLY B O   1 
ATOM   4232  N N   . THR B 1 157 ? -1.394  -29.249 15.901  1.00 24.36  ? 157 THR B N   1 
ATOM   4233  C CA  . THR B 1 157 ? -0.622  -30.448 16.227  1.00 25.43  ? 157 THR B CA  1 
ATOM   4234  C C   . THR B 1 157 ? 0.266   -30.183 17.438  1.00 23.91  ? 157 THR B C   1 
ATOM   4235  O O   . THR B 1 157 ? 0.923   -29.139 17.497  1.00 26.90  ? 157 THR B O   1 
ATOM   4236  C CB  . THR B 1 157 ? 0.223   -30.845 15.019  1.00 22.60  ? 157 THR B CB  1 
ATOM   4237  O OG1 . THR B 1 157 ? -0.632  -30.969 13.879  1.00 24.49  ? 157 THR B OG1 1 
ATOM   4238  C CG2 . THR B 1 157 ? 0.924   -32.166 15.234  1.00 25.31  ? 157 THR B CG2 1 
ATOM   4239  N N   . PRO B 1 158 ? 0.298   -31.078 18.422  1.00 27.04  ? 158 PRO B N   1 
ATOM   4240  C CA  . PRO B 1 158 ? 1.205   -30.895 19.572  1.00 29.92  ? 158 PRO B CA  1 
ATOM   4241  C C   . PRO B 1 158 ? 2.650   -30.672 19.128  1.00 30.34  ? 158 PRO B C   1 
ATOM   4242  O O   . PRO B 1 158 ? 3.194   -31.400 18.292  1.00 26.96  ? 158 PRO B O   1 
ATOM   4243  C CB  . PRO B 1 158 ? 1.058   -32.198 20.364  1.00 29.45  ? 158 PRO B CB  1 
ATOM   4244  C CG  . PRO B 1 158 ? -0.101  -32.922 19.797  1.00 26.89  ? 158 PRO B CG  1 
ATOM   4245  C CD  . PRO B 1 158 ? -0.490  -32.319 18.491  1.00 25.84  ? 158 PRO B CD  1 
ATOM   4246  N N   . LEU B 1 159 ? 3.266   -29.662 19.721  1.00 28.82  ? 159 LEU B N   1 
ATOM   4247  C CA  . LEU B 1 159 ? 4.499   -29.059 19.262  1.00 29.78  ? 159 LEU B CA  1 
ATOM   4248  C C   . LEU B 1 159 ? 5.189   -28.527 20.506  1.00 31.03  ? 159 LEU B C   1 
ATOM   4249  O O   . LEU B 1 159 ? 4.542   -27.861 21.318  1.00 35.52  ? 159 LEU B O   1 
ATOM   4250  C CB  . LEU B 1 159 ? 4.193   -27.922 18.278  1.00 27.86  ? 159 LEU B CB  1 
ATOM   4251  C CG  . LEU B 1 159 ? 5.373   -27.222 17.610  1.00 30.78  ? 159 LEU B CG  1 
ATOM   4252  C CD1 . LEU B 1 159 ? 6.089   -28.173 16.674  1.00 32.62  ? 159 LEU B CD1 1 
ATOM   4253  C CD2 . LEU B 1 159 ? 4.932   -25.952 16.873  1.00 29.86  ? 159 LEU B CD2 1 
ATOM   4254  N N   . THR B 1 160 ? 6.467   -28.840 20.696  1.00 27.33  ? 160 THR B N   1 
ATOM   4255  C CA  . THR B 1 160 ? 7.106   -28.267 21.869  1.00 27.04  ? 160 THR B CA  1 
ATOM   4256  C C   . THR B 1 160 ? 7.196   -26.752 21.694  1.00 26.63  ? 160 THR B C   1 
ATOM   4257  O O   . THR B 1 160 ? 7.093   -26.217 20.581  1.00 26.29  ? 160 THR B O   1 
ATOM   4258  C CB  . THR B 1 160 ? 8.493   -28.893 22.144  1.00 29.70  ? 160 THR B CB  1 
ATOM   4259  O OG1 . THR B 1 160 ? 9.518   -28.215 21.399  1.00 34.86  ? 160 THR B OG1 1 
ATOM   4260  C CG2 . THR B 1 160 ? 8.519   -30.371 21.811  1.00 27.40  ? 160 THR B CG2 1 
ATOM   4261  N N   . ASP B 1 161 ? 7.327   -26.061 22.820  1.00 17.81  ? 161 ASP B N   1 
ATOM   4262  C CA  . ASP B 1 161 ? 7.585   -24.635 22.794  1.00 27.64  ? 161 ASP B CA  1 
ATOM   4263  C C   . ASP B 1 161 ? 8.848   -24.349 22.002  1.00 26.77  ? 161 ASP B C   1 
ATOM   4264  O O   . ASP B 1 161 ? 9.879   -24.990 22.208  1.00 28.24  ? 161 ASP B O   1 
ATOM   4265  C CB  . ASP B 1 161 ? 7.736   -24.096 24.212  1.00 30.83  ? 161 ASP B CB  1 
ATOM   4266  C CG  . ASP B 1 161 ? 6.444   -23.544 24.761  1.00 41.81  ? 161 ASP B CG  1 
ATOM   4267  O OD1 . ASP B 1 161 ? 5.372   -24.132 24.478  1.00 34.57  ? 161 ASP B OD1 1 
ATOM   4268  O OD2 . ASP B 1 161 ? 6.509   -22.498 25.448  1.00 46.97  ? 161 ASP B OD2 1 
ATOM   4269  N N   . GLY B 1 162 ? 8.779   -23.378 21.106  1.00 25.87  ? 162 GLY B N   1 
ATOM   4270  C CA  . GLY B 1 162 ? 9.957   -23.115 20.310  1.00 28.09  ? 162 GLY B CA  1 
ATOM   4271  C C   . GLY B 1 162 ? 9.804   -21.833 19.534  1.00 30.78  ? 162 GLY B C   1 
ATOM   4272  O O   . GLY B 1 162 ? 8.722   -21.240 19.473  1.00 29.13  ? 162 GLY B O   1 
ATOM   4273  N N   . VAL B 1 163 ? 10.917  -21.425 18.931  1.00 26.03  ? 163 VAL B N   1 
ATOM   4274  C CA  . VAL B 1 163 ? 11.004  -20.211 18.135  1.00 26.95  ? 163 VAL B CA  1 
ATOM   4275  C C   . VAL B 1 163 ? 11.643  -20.552 16.791  1.00 25.82  ? 163 VAL B C   1 
ATOM   4276  O O   . VAL B 1 163 ? 12.616  -21.317 16.731  1.00 28.87  ? 163 VAL B O   1 
ATOM   4277  C CB  . VAL B 1 163 ? 11.819  -19.127 18.889  1.00 24.81  ? 163 VAL B CB  1 
ATOM   4278  C CG1 . VAL B 1 163 ? 12.085  -17.916 18.020  1.00 23.01  ? 163 VAL B CG1 1 
ATOM   4279  C CG2 . VAL B 1 163 ? 11.094  -18.704 20.178  1.00 25.33  ? 163 VAL B CG2 1 
ATOM   4280  N N   . VAL B 1 164 ? 11.094  -19.986 15.713  1.00 24.69  ? 164 VAL B N   1 
ATOM   4281  C CA  . VAL B 1 164 ? 11.793  -19.893 14.432  1.00 22.20  ? 164 VAL B CA  1 
ATOM   4282  C C   . VAL B 1 164 ? 12.660  -18.644 14.477  1.00 26.31  ? 164 VAL B C   1 
ATOM   4283  O O   . VAL B 1 164 ? 12.208  -17.545 14.142  1.00 23.54  ? 164 VAL B O   1 
ATOM   4284  C CB  . VAL B 1 164 ? 10.813  -19.861 13.240  1.00 25.74  ? 164 VAL B CB  1 
ATOM   4285  C CG1 . VAL B 1 164 ? 11.540  -19.578 11.915  1.00 25.67  ? 164 VAL B CG1 1 
ATOM   4286  C CG2 . VAL B 1 164 ? 10.046  -21.185 13.140  1.00 23.70  ? 164 VAL B CG2 1 
ATOM   4287  N N   . ALA B 1 165 ? 13.909  -18.815 14.912  1.00 23.89  ? 165 ALA B N   1 
ATOM   4288  C CA  . ALA B 1 165 ? 14.839  -17.718 15.121  1.00 21.04  ? 165 ALA B CA  1 
ATOM   4289  C C   . ALA B 1 165 ? 15.358  -17.129 13.805  1.00 29.53  ? 165 ALA B C   1 
ATOM   4290  O O   . ALA B 1 165 ? 15.717  -17.853 12.871  1.00 26.45  ? 165 ALA B O   1 
ATOM   4291  C CB  . ALA B 1 165 ? 16.024  -18.200 15.962  1.00 24.46  ? 165 ALA B CB  1 
ATOM   4292  N N   . ARG B 1 166 ? 15.451  -15.796 13.755  1.00 24.93  ? 166 ARG B N   1 
ATOM   4293  C CA  . ARG B 1 166 ? 15.876  -15.091 12.555  1.00 23.64  ? 166 ARG B CA  1 
ATOM   4294  C C   . ARG B 1 166 ? 17.221  -14.386 12.694  1.00 28.68  ? 166 ARG B C   1 
ATOM   4295  O O   . ARG B 1 166 ? 17.752  -13.896 11.685  1.00 23.22  ? 166 ARG B O   1 
ATOM   4296  C CB  . ARG B 1 166 ? 14.805  -14.071 12.139  1.00 24.37  ? 166 ARG B CB  1 
ATOM   4297  C CG  . ARG B 1 166 ? 13.497  -14.738 11.703  1.00 26.21  ? 166 ARG B CG  1 
ATOM   4298  C CD  . ARG B 1 166 ? 12.298  -13.784 11.667  1.00 30.07  ? 166 ARG B CD  1 
ATOM   4299  N NE  . ARG B 1 166 ? 11.899  -13.335 12.997  1.00 30.06  ? 166 ARG B NE  1 
ATOM   4300  C CZ  . ARG B 1 166 ? 10.893  -12.503 13.227  1.00 31.16  ? 166 ARG B CZ  1 
ATOM   4301  N NH1 . ARG B 1 166 ? 10.168  -12.016 12.231  1.00 31.13  ? 166 ARG B NH1 1 
ATOM   4302  N NH2 . ARG B 1 166 ? 10.599  -12.163 14.490  1.00 24.42  ? 166 ARG B NH2 1 
ATOM   4303  N N   . GLY B 1 167 ? 17.800  -14.332 13.892  1.00 28.17  ? 167 GLY B N   1 
ATOM   4304  C CA  . GLY B 1 167 ? 19.105  -13.730 14.052  1.00 26.89  ? 167 GLY B CA  1 
ATOM   4305  C C   . GLY B 1 167 ? 19.751  -14.112 15.361  1.00 26.23  ? 167 GLY B C   1 
ATOM   4306  O O   . GLY B 1 167 ? 19.129  -14.763 16.208  1.00 31.05  ? 167 GLY B O   1 
ATOM   4307  N N   . PRO B 1 168 ? 21.018  -13.723 15.556  1.00 24.74  ? 168 PRO B N   1 
ATOM   4308  C CA  . PRO B 1 168 ? 21.683  -14.058 16.824  1.00 29.33  ? 168 PRO B CA  1 
ATOM   4309  C C   . PRO B 1 168 ? 20.921  -13.552 18.030  1.00 29.62  ? 168 PRO B C   1 
ATOM   4310  O O   . PRO B 1 168 ? 20.826  -14.270 19.035  1.00 28.20  ? 168 PRO B O   1 
ATOM   4311  C CB  . PRO B 1 168 ? 23.062  -13.389 16.696  1.00 31.71  ? 168 PRO B CB  1 
ATOM   4312  C CG  . PRO B 1 168 ? 23.269  -13.171 15.266  1.00 27.68  ? 168 PRO B CG  1 
ATOM   4313  C CD  . PRO B 1 168 ? 21.904  -12.989 14.645  1.00 28.31  ? 168 PRO B CD  1 
ATOM   4314  N N   . ALA B 1 169 ? 20.334  -12.348 17.937  1.00 29.74  ? 169 ALA B N   1 
ATOM   4315  C CA  . ALA B 1 169 ? 19.601  -11.786 19.066  1.00 27.50  ? 169 ALA B CA  1 
ATOM   4316  C C   . ALA B 1 169 ? 18.355  -12.600 19.359  1.00 29.05  ? 169 ALA B C   1 
ATOM   4317  O O   . ALA B 1 169 ? 18.030  -12.849 20.522  1.00 31.93  ? 169 ALA B O   1 
ATOM   4318  C CB  . ALA B 1 169 ? 19.236  -10.313 18.807  1.00 27.99  ? 169 ALA B CB  1 
ATOM   4319  N N   . GLU B 1 170 ? 17.664  -13.063 18.320  1.00 31.45  ? 170 GLU B N   1 
ATOM   4320  C CA  . GLU B 1 170 ? 16.512  -13.918 18.562  1.00 27.63  ? 170 GLU B CA  1 
ATOM   4321  C C   . GLU B 1 170 ? 16.929  -15.303 19.063  1.00 23.79  ? 170 GLU B C   1 
ATOM   4322  O O   . GLU B 1 170 ? 16.236  -15.884 19.905  1.00 24.13  ? 170 GLU B O   1 
ATOM   4323  C CB  . GLU B 1 170 ? 15.658  -14.004 17.297  1.00 29.95  ? 170 GLU B CB  1 
ATOM   4324  C CG  . GLU B 1 170 ? 14.213  -14.361 17.589  1.00 30.18  ? 170 GLU B CG  1 
ATOM   4325  C CD  . GLU B 1 170 ? 13.238  -14.080 16.430  1.00 31.15  ? 170 GLU B CD  1 
ATOM   4326  O OE1 . GLU B 1 170 ? 13.634  -14.110 15.240  1.00 22.87  ? 170 GLU B OE1 1 
ATOM   4327  O OE2 . GLU B 1 170 ? 12.044  -13.853 16.740  1.00 29.24  ? 170 GLU B OE2 1 
ATOM   4328  N N   . VAL B 1 171 ? 18.054  -15.845 18.588  1.00 26.06  ? 171 VAL B N   1 
ATOM   4329  C CA  . VAL B 1 171 ? 18.573  -17.070 19.200  1.00 23.31  ? 171 VAL B CA  1 
ATOM   4330  C C   . VAL B 1 171 ? 18.803  -16.846 20.695  1.00 28.75  ? 171 VAL B C   1 
ATOM   4331  O O   . VAL B 1 171 ? 18.473  -17.700 21.533  1.00 30.63  ? 171 VAL B O   1 
ATOM   4332  C CB  . VAL B 1 171 ? 19.852  -17.544 18.478  1.00 26.82  ? 171 VAL B CB  1 
ATOM   4333  C CG1 . VAL B 1 171 ? 20.545  -18.631 19.296  1.00 26.45  ? 171 VAL B CG1 1 
ATOM   4334  C CG2 . VAL B 1 171 ? 19.516  -18.099 17.101  1.00 22.71  ? 171 VAL B CG2 1 
ATOM   4335  N N   . ARG B 1 172 ? 19.291  -15.656 21.054  1.00 31.76  ? 172 ARG B N   1 
ATOM   4336  C CA  . ARG B 1 172 ? 19.627  -15.357 22.443  1.00 28.04  ? 172 ARG B CA  1 
ATOM   4337  C C   . ARG B 1 172 ? 18.389  -15.337 23.330  1.00 27.19  ? 172 ARG B C   1 
ATOM   4338  O O   . ARG B 1 172 ? 18.346  -16.011 24.365  1.00 30.42  ? 172 ARG B O   1 
ATOM   4339  C CB  . ARG B 1 172 ? 20.359  -14.010 22.528  1.00 26.54  ? 172 ARG B CB  1 
ATOM   4340  C CG  . ARG B 1 172 ? 21.031  -13.772 23.859  1.00 37.34  ? 172 ARG B CG  1 
ATOM   4341  C CD  . ARG B 1 172 ? 21.421  -12.309 24.049  1.00 46.39  ? 172 ARG B CD  1 
ATOM   4342  N NE  . ARG B 1 172 ? 22.277  -12.091 25.211  1.00 46.92  ? 172 ARG B NE  1 
ATOM   4343  C CZ  . ARG B 1 172 ? 21.953  -12.379 26.467  1.00 55.38  ? 172 ARG B CZ  1 
ATOM   4344  N NH1 . ARG B 1 172 ? 20.789  -12.927 26.779  1.00 48.87  ? 172 ARG B NH1 1 
ATOM   4345  N NH2 . ARG B 1 172 ? 22.822  -12.110 27.440  1.00 60.52  ? 172 ARG B NH2 1 
ATOM   4346  N N   . SER B 1 173 ? 17.384  -14.532 22.980  1.00 22.44  ? 173 SER B N   1 
ATOM   4347  C CA  . SER B 1 173 ? 16.203  -14.468 23.842  1.00 27.50  ? 173 SER B CA  1 
ATOM   4348  C C   . SER B 1 173 ? 15.437  -15.793 23.843  1.00 29.05  ? 173 SER B C   1 
ATOM   4349  O O   . SER B 1 173 ? 14.906  -16.209 24.880  1.00 33.90  ? 173 SER B O   1 
ATOM   4350  C CB  . SER B 1 173 ? 15.291  -13.312 23.425  1.00 31.01  ? 173 SER B CB  1 
ATOM   4351  O OG  . SER B 1 173 ? 15.053  -13.302 22.028  1.00 35.47  ? 173 SER B OG  1 
ATOM   4352  N N   . ALA B 1 174 ? 15.366  -16.466 22.694  1.00 30.92  ? 174 ALA B N   1 
ATOM   4353  C CA  . ALA B 1 174 ? 14.751  -17.788 22.643  1.00 26.81  ? 174 ALA B CA  1 
ATOM   4354  C C   . ALA B 1 174 ? 15.350  -18.704 23.699  1.00 28.76  ? 174 ALA B C   1 
ATOM   4355  O O   . ALA B 1 174 ? 14.625  -19.340 24.473  1.00 31.02  ? 174 ALA B O   1 
ATOM   4356  C CB  . ALA B 1 174 ? 14.922  -18.393 21.248  1.00 25.89  ? 174 ALA B CB  1 
ATOM   4357  N N   . ILE B 1 175 ? 16.680  -18.757 23.772  1.00 30.96  ? 175 ILE B N   1 
ATOM   4358  C CA  . ILE B 1 175 ? 17.317  -19.659 24.729  1.00 31.80  ? 175 ILE B CA  1 
ATOM   4359  C C   . ILE B 1 175 ? 16.977  -19.251 26.157  1.00 36.81  ? 175 ILE B C   1 
ATOM   4360  O O   . ILE B 1 175 ? 16.751  -20.109 27.023  1.00 37.89  ? 175 ILE B O   1 
ATOM   4361  C CB  . ILE B 1 175 ? 18.838  -19.713 24.507  1.00 32.31  ? 175 ILE B CB  1 
ATOM   4362  C CG1 . ILE B 1 175 ? 19.171  -20.550 23.284  1.00 32.49  ? 175 ILE B CG1 1 
ATOM   4363  C CG2 . ILE B 1 175 ? 19.514  -20.343 25.695  1.00 37.76  ? 175 ILE B CG2 1 
ATOM   4364  C CD1 . ILE B 1 175 ? 20.494  -20.158 22.641  1.00 37.43  ? 175 ILE B CD1 1 
ATOM   4365  N N   . GLN B 1 176 ? 16.912  -17.938 26.423  1.00 36.05  ? 176 GLN B N   1 
ATOM   4366  C CA  . GLN B 1 176 ? 16.592  -17.451 27.764  1.00 40.00  ? 176 GLN B CA  1 
ATOM   4367  C C   . GLN B 1 176 ? 15.207  -17.898 28.200  1.00 41.97  ? 176 GLN B C   1 
ATOM   4368  O O   . GLN B 1 176 ? 15.036  -18.481 29.276  1.00 44.32  ? 176 GLN B O   1 
ATOM   4369  C CB  . GLN B 1 176 ? 16.673  -15.927 27.810  1.00 42.86  ? 176 GLN B CB  1 
ATOM   4370  C CG  . GLN B 1 176 ? 18.066  -15.392 27.701  1.00 45.69  ? 176 GLN B CG  1 
ATOM   4371  C CD  . GLN B 1 176 ? 18.351  -14.350 28.747  1.00 55.68  ? 176 GLN B CD  1 
ATOM   4372  O OE1 . GLN B 1 176 ? 19.429  -14.331 29.345  1.00 58.98  ? 176 GLN B OE1 1 
ATOM   4373  N NE2 . GLN B 1 176 ? 17.382  -13.470 28.981  1.00 57.25  ? 176 GLN B NE2 1 
ATOM   4374  N N   . GLU B 1 177 ? 14.195  -17.585 27.390  1.00 38.77  ? 177 GLU B N   1 
ATOM   4375  C CA  . GLU B 1 177 ? 12.830  -17.969 27.726  1.00 43.55  ? 177 GLU B CA  1 
ATOM   4376  C C   . GLU B 1 177 ? 12.689  -19.486 27.791  1.00 42.77  ? 177 GLU B C   1 
ATOM   4377  O O   . GLU B 1 177 ? 12.116  -20.033 28.745  1.00 43.90  ? 177 GLU B O   1 
ATOM   4378  C CB  . GLU B 1 177 ? 11.860  -17.377 26.702  1.00 37.51  ? 177 GLU B CB  1 
ATOM   4379  C CG  . GLU B 1 177 ? 10.573  -16.813 27.301  1.00 52.02  ? 177 GLU B CG  1 
ATOM   4380  C CD  . GLU B 1 177 ? 9.462   -16.657 26.264  1.00 61.60  ? 177 GLU B CD  1 
ATOM   4381  O OE1 . GLU B 1 177 ? 8.270   -16.589 26.656  1.00 63.52  ? 177 GLU B OE1 1 
ATOM   4382  O OE2 . GLU B 1 177 ? 9.780   -16.610 25.053  1.00 55.52  ? 177 GLU B OE2 1 
ATOM   4383  N N   . LEU B 1 178 ? 13.218  -20.187 26.789  1.00 33.06  ? 178 LEU B N   1 
ATOM   4384  C CA  . LEU B 1 178 ? 12.883  -21.592 26.629  1.00 29.85  ? 178 LEU B CA  1 
ATOM   4385  C C   . LEU B 1 178 ? 13.633  -22.495 27.600  1.00 30.97  ? 178 LEU B C   1 
ATOM   4386  O O   . LEU B 1 178 ? 13.229  -23.648 27.787  1.00 32.34  ? 178 LEU B O   1 
ATOM   4387  C CB  . LEU B 1 178 ? 13.154  -22.020 25.182  1.00 31.58  ? 178 LEU B CB  1 
ATOM   4388  C CG  . LEU B 1 178 ? 12.291  -21.249 24.178  1.00 33.63  ? 178 LEU B CG  1 
ATOM   4389  C CD1 . LEU B 1 178 ? 12.622  -21.673 22.768  1.00 31.17  ? 178 LEU B CD1 1 
ATOM   4390  C CD2 . LEU B 1 178 ? 10.791  -21.405 24.467  1.00 29.41  ? 178 LEU B CD2 1 
ATOM   4391  N N   . ILE B 1 179 ? 14.695  -21.996 28.236  1.00 31.06  ? 179 ILE B N   1 
ATOM   4392  C CA  . ILE B 1 179 ? 15.506  -22.837 29.106  1.00 32.49  ? 179 ILE B CA  1 
ATOM   4393  C C   . ILE B 1 179 ? 14.806  -23.153 30.417  1.00 34.54  ? 179 ILE B C   1 
ATOM   4394  O O   . ILE B 1 179 ? 15.197  -24.102 31.104  1.00 40.01  ? 179 ILE B O   1 
ATOM   4395  C CB  . ILE B 1 179 ? 16.867  -22.167 29.374  1.00 32.74  ? 179 ILE B CB  1 
ATOM   4396  C CG1 . ILE B 1 179 ? 17.882  -23.193 29.849  1.00 32.48  ? 179 ILE B CG1 1 
ATOM   4397  C CG2 . ILE B 1 179 ? 16.723  -21.022 30.380  1.00 31.99  ? 179 ILE B CG2 1 
ATOM   4398  C CD1 . ILE B 1 179 ? 18.520  -23.965 28.739  1.00 33.15  ? 179 ILE B CD1 1 
ATOM   4399  N N   . ALA B 1 180 ? 13.777  -22.391 30.792  1.00 33.77  ? 180 ALA B N   1 
ATOM   4400  C CA  . ALA B 1 180 ? 13.223  -22.520 32.139  1.00 37.45  ? 180 ALA B CA  1 
ATOM   4401  C C   . ALA B 1 180 ? 12.547  -23.872 32.341  1.00 43.11  ? 180 ALA B C   1 
ATOM   4402  O O   . ALA B 1 180 ? 12.786  -24.549 33.350  1.00 45.83  ? 180 ALA B O   1 
ATOM   4403  C CB  . ALA B 1 180 ? 12.237  -21.386 32.421  1.00 33.11  ? 180 ALA B CB  1 
ATOM   4404  N N   . GLU B 1 181 ? 11.721  -24.294 31.372  1.00 42.41  ? 181 GLU B N   1 
ATOM   4405  C CA  . GLU B 1 181 ? 10.800  -25.407 31.600  1.00 34.22  ? 181 GLU B CA  1 
ATOM   4406  C C   . GLU B 1 181 ? 11.527  -26.682 31.986  1.00 32.84  ? 181 GLU B C   1 
ATOM   4407  O O   . GLU B 1 181 ? 11.077  -27.406 32.878  1.00 38.92  ? 181 GLU B O   1 
ATOM   4408  C CB  . GLU B 1 181 ? 9.939   -25.653 30.360  1.00 38.36  ? 181 GLU B CB  1 
ATOM   4409  C CG  . GLU B 1 181 ? 8.733   -26.534 30.624  1.00 37.75  ? 181 GLU B CG  1 
ATOM   4410  C CD  . GLU B 1 181 ? 8.032   -26.996 29.355  1.00 41.77  ? 181 GLU B CD  1 
ATOM   4411  O OE1 . GLU B 1 181 ? 8.032   -26.221 28.372  1.00 44.63  ? 181 GLU B OE1 1 
ATOM   4412  O OE2 . GLU B 1 181 ? 7.457   -28.117 29.348  1.00 44.17  ? 181 GLU B OE2 1 
ATOM   4413  N N   . THR B 1 182 ? 12.632  -26.989 31.311  1.00 36.78  ? 182 THR B N   1 
ATOM   4414  C CA  . THR B 1 182 ? 13.353  -28.238 31.519  1.00 31.73  ? 182 THR B CA  1 
ATOM   4415  C C   . THR B 1 182 ? 14.832  -28.057 31.833  1.00 29.59  ? 182 THR B C   1 
ATOM   4416  O O   . THR B 1 182 ? 15.500  -29.051 32.125  1.00 39.43  ? 182 THR B O   1 
ATOM   4417  C CB  . THR B 1 182 ? 13.246  -29.143 30.273  1.00 31.64  ? 182 THR B CB  1 
ATOM   4418  O OG1 . THR B 1 182 ? 14.065  -28.615 29.219  1.00 26.30  ? 182 THR B OG1 1 
ATOM   4419  C CG2 . THR B 1 182 ? 11.819  -29.224 29.779  1.00 32.32  ? 182 THR B CG2 1 
ATOM   4420  N N   . GLY B 1 183 ? 15.373  -26.849 31.765  1.00 30.52  ? 183 GLY B N   1 
ATOM   4421  C CA  . GLY B 1 183 ? 16.816  -26.731 31.814  1.00 30.17  ? 183 GLY B CA  1 
ATOM   4422  C C   . GLY B 1 183 ? 17.529  -27.261 30.586  1.00 37.48  ? 183 GLY B C   1 
ATOM   4423  O O   . GLY B 1 183 ? 18.764  -27.366 30.595  1.00 33.16  ? 183 GLY B O   1 
ATOM   4424  N N   . MET B 1 184 ? 16.787  -27.610 29.529  1.00 36.26  ? 184 MET B N   1 
ATOM   4425  C CA  . MET B 1 184 ? 17.362  -28.099 28.281  1.00 29.21  ? 184 MET B CA  1 
ATOM   4426  C C   . MET B 1 184 ? 16.709  -27.402 27.099  1.00 28.90  ? 184 MET B C   1 
ATOM   4427  O O   . MET B 1 184 ? 15.486  -27.242 27.060  1.00 24.40  ? 184 MET B O   1 
ATOM   4428  C CB  . MET B 1 184 ? 17.193  -29.603 28.152  1.00 28.73  ? 184 MET B CB  1 
ATOM   4429  C CG  . MET B 1 184 ? 17.591  -30.386 29.398  1.00 34.37  ? 184 MET B CG  1 
ATOM   4430  S SD  . MET B 1 184 ? 17.429  -32.168 29.216  1.00 36.83  ? 184 MET B SD  1 
ATOM   4431  C CE  . MET B 1 184 ? 18.404  -32.540 27.777  1.00 45.20  ? 184 MET B CE  1 
ATOM   4432  N N   . VAL B 1 185 ? 17.528  -27.003 26.132  1.00 27.53  ? 185 VAL B N   1 
ATOM   4433  C CA  . VAL B 1 185 ? 17.059  -26.463 24.873  1.00 21.62  ? 185 VAL B CA  1 
ATOM   4434  C C   . VAL B 1 185 ? 17.847  -27.139 23.761  1.00 32.11  ? 185 VAL B C   1 
ATOM   4435  O O   . VAL B 1 185 ? 18.976  -27.596 23.974  1.00 31.32  ? 185 VAL B O   1 
ATOM   4436  C CB  . VAL B 1 185 ? 17.211  -24.930 24.851  1.00 27.81  ? 185 VAL B CB  1 
ATOM   4437  C CG1 . VAL B 1 185 ? 17.166  -24.380 23.444  1.00 28.26  ? 185 VAL B CG1 1 
ATOM   4438  C CG2 . VAL B 1 185 ? 16.126  -24.289 25.706  1.00 28.07  ? 185 VAL B CG2 1 
ATOM   4439  N N   . ILE B 1 186 ? 17.234  -27.242 22.577  1.00 26.01  ? 186 ILE B N   1 
ATOM   4440  C CA  . ILE B 1 186 ? 17.903  -27.779 21.397  1.00 24.89  ? 186 ILE B CA  1 
ATOM   4441  C C   . ILE B 1 186 ? 17.805  -26.764 20.262  1.00 30.11  ? 186 ILE B C   1 
ATOM   4442  O O   . ILE B 1 186 ? 16.715  -26.258 19.965  1.00 27.71  ? 186 ILE B O   1 
ATOM   4443  C CB  . ILE B 1 186 ? 17.318  -29.139 20.990  1.00 26.59  ? 186 ILE B CB  1 
ATOM   4444  C CG1 . ILE B 1 186 ? 18.234  -29.824 19.980  1.00 33.71  ? 186 ILE B CG1 1 
ATOM   4445  C CG2 . ILE B 1 186 ? 15.861  -29.026 20.501  1.00 29.53  ? 186 ILE B CG2 1 
ATOM   4446  C CD1 . ILE B 1 186 ? 17.809  -31.247 19.664  1.00 34.63  ? 186 ILE B CD1 1 
ATOM   4447  N N   . ALA B 1 187 ? 18.950  -26.419 19.676  1.00 24.19  ? 187 ALA B N   1 
ATOM   4448  C CA  . ALA B 1 187 ? 19.025  -25.547 18.512  1.00 25.27  ? 187 ALA B CA  1 
ATOM   4449  C C   . ALA B 1 187 ? 19.283  -26.384 17.272  1.00 24.92  ? 187 ALA B C   1 
ATOM   4450  O O   . ALA B 1 187 ? 20.261  -27.142 17.231  1.00 28.82  ? 187 ALA B O   1 
ATOM   4451  C CB  . ALA B 1 187 ? 20.133  -24.511 18.656  1.00 22.27  ? 187 ALA B CB  1 
ATOM   4452  N N   . LYS B 1 188 ? 18.451  -26.208 16.247  1.00 20.24  ? 188 LYS B N   1 
ATOM   4453  C CA  . LYS B 1 188 ? 18.446  -27.092 15.090  1.00 25.60  ? 188 LYS B CA  1 
ATOM   4454  C C   . LYS B 1 188 ? 18.670  -26.317 13.804  1.00 27.62  ? 188 LYS B C   1 
ATOM   4455  O O   . LYS B 1 188 ? 18.059  -25.259 13.591  1.00 26.82  ? 188 LYS B O   1 
ATOM   4456  C CB  . LYS B 1 188 ? 17.127  -27.860 14.991  1.00 28.80  ? 188 LYS B CB  1 
ATOM   4457  C CG  . LYS B 1 188 ? 16.900  -28.878 16.110  1.00 23.12  ? 188 LYS B CG  1 
ATOM   4458  C CD  . LYS B 1 188 ? 15.471  -29.405 16.062  1.00 35.74  ? 188 LYS B CD  1 
ATOM   4459  C CE  . LYS B 1 188 ? 15.255  -30.570 17.028  1.00 44.14  ? 188 LYS B CE  1 
ATOM   4460  N NZ  . LYS B 1 188 ? 13.846  -31.093 16.959  1.00 48.80  ? 188 LYS B NZ  1 
ATOM   4461  N N   . GLN B 1 189 ? 19.548  -26.854 12.955  1.00 29.22  ? 189 GLN B N   1 
ATOM   4462  C CA  . GLN B 1 189 ? 19.649  -26.403 11.573  1.00 31.07  ? 189 GLN B CA  1 
ATOM   4463  C C   . GLN B 1 189 ? 18.318  -26.624 10.862  1.00 30.33  ? 189 GLN B C   1 
ATOM   4464  O O   . GLN B 1 189 ? 17.626  -27.616 11.092  1.00 30.94  ? 189 GLN B O   1 
ATOM   4465  C CB  . GLN B 1 189 ? 20.766  -27.165 10.859  1.00 36.89  ? 189 GLN B CB  1 
ATOM   4466  C CG  . GLN B 1 189 ? 21.437  -26.440 9.684   1.00 43.49  ? 189 GLN B CG  1 
ATOM   4467  C CD  . GLN B 1 189 ? 22.398  -27.350 8.882   1.00 54.99  ? 189 GLN B CD  1 
ATOM   4468  O OE1 . GLN B 1 189 ? 22.501  -28.558 9.146   1.00 48.88  ? 189 GLN B OE1 1 
ATOM   4469  N NE2 . GLN B 1 189 ? 23.087  -26.765 7.886   1.00 55.85  ? 189 GLN B NE2 1 
ATOM   4470  N N   . ASP B 1 190 ? 17.959  -25.689 9.990   1.00 33.07  ? 190 ASP B N   1 
ATOM   4471  C CA  . ASP B 1 190 ? 16.619  -25.700 9.405   1.00 35.36  ? 190 ASP B CA  1 
ATOM   4472  C C   . ASP B 1 190 ? 16.405  -26.879 8.447   1.00 34.34  ? 190 ASP B C   1 
ATOM   4473  O O   . ASP B 1 190 ? 15.299  -27.425 8.391   1.00 32.29  ? 190 ASP B O   1 
ATOM   4474  C CB  . ASP B 1 190 ? 16.368  -24.365 8.707   1.00 34.70  ? 190 ASP B CB  1 
ATOM   4475  C CG  . ASP B 1 190 ? 14.892  -24.051 8.548   1.00 30.79  ? 190 ASP B CG  1 
ATOM   4476  O OD1 . ASP B 1 190 ? 14.069  -24.606 9.299   1.00 28.39  ? 190 ASP B OD1 1 
ATOM   4477  O OD2 . ASP B 1 190 ? 14.560  -23.253 7.649   1.00 33.56  ? 190 ASP B OD2 1 
ATOM   4478  N N   . ARG B 1 191 ? 17.442  -27.314 7.722   1.00 36.35  ? 191 ARG B N   1 
ATOM   4479  C CA  . ARG B 1 191 ? 17.318  -28.397 6.748   1.00 40.38  ? 191 ARG B CA  1 
ATOM   4480  C C   . ARG B 1 191 ? 18.119  -29.648 7.110   1.00 52.45  ? 191 ARG B C   1 
ATOM   4481  O O   . ARG B 1 191 ? 18.422  -30.457 6.223   1.00 57.70  ? 191 ARG B O   1 
ATOM   4482  C CB  . ARG B 1 191 ? 17.745  -27.897 5.374   1.00 41.26  ? 191 ARG B CB  1 
ATOM   4483  C CG  . ARG B 1 191 ? 17.301  -26.490 5.103   1.00 46.83  ? 191 ARG B CG  1 
ATOM   4484  C CD  . ARG B 1 191 ? 17.279  -26.180 3.615   1.00 50.15  ? 191 ARG B CD  1 
ATOM   4485  N NE  . ARG B 1 191 ? 16.089  -26.679 2.938   1.00 46.45  ? 191 ARG B NE  1 
ATOM   4486  C CZ  . ARG B 1 191 ? 15.349  -25.957 2.104   1.00 52.17  ? 191 ARG B CZ  1 
ATOM   4487  N NH1 . ARG B 1 191 ? 15.608  -24.670 1.880   1.00 37.48  ? 191 ARG B NH1 1 
ATOM   4488  N NH2 . ARG B 1 191 ? 14.324  -26.536 1.483   1.00 44.90  ? 191 ARG B NH2 1 
ATOM   4489  N N   . SER B 1 192 ? 18.431  -29.854 8.393   1.00 57.20  ? 192 SER B N   1 
ATOM   4490  C CA  . SER B 1 192 ? 19.492  -30.785 8.782   1.00 60.32  ? 192 SER B CA  1 
ATOM   4491  C C   . SER B 1 192 ? 19.152  -32.236 8.417   1.00 63.12  ? 192 SER B C   1 
ATOM   4492  O O   . SER B 1 192 ? 18.019  -32.586 8.056   1.00 56.18  ? 192 SER B O   1 
ATOM   4493  C CB  . SER B 1 192 ? 19.788  -30.684 10.285  1.00 56.33  ? 192 SER B CB  1 
ATOM   4494  O OG  . SER B 1 192 ? 18.827  -31.391 11.066  1.00 56.52  ? 192 SER B OG  1 
ATOM   4495  N N   . GLY B 1 193 ? 20.179  -33.082 8.504   1.00 63.21  ? 193 GLY B N   1 
ATOM   4496  C CA  . GLY B 1 193 ? 20.023  -34.510 8.324   1.00 67.04  ? 193 GLY B CA  1 
ATOM   4497  C C   . GLY B 1 193 ? 20.202  -35.238 9.637   1.00 63.53  ? 193 GLY B C   1 
ATOM   4498  O O   . GLY B 1 193 ? 21.330  -35.557 10.032  1.00 66.59  ? 193 GLY B O   1 
ATOM   4499  N N   . GLY B 1 194 ? 19.089  -35.502 10.320  1.00 66.87  ? 194 GLY B N   1 
ATOM   4500  C CA  . GLY B 1 194 ? 19.106  -36.014 11.677  1.00 67.53  ? 194 GLY B CA  1 
ATOM   4501  C C   . GLY B 1 194 ? 19.852  -35.058 12.589  1.00 61.47  ? 194 GLY B C   1 
ATOM   4502  O O   . GLY B 1 194 ? 19.988  -33.861 12.308  1.00 55.62  ? 194 GLY B O   1 
ATOM   4503  N N   . GLY B 1 195 ? 20.349  -35.590 13.699  1.00 58.62  ? 195 GLY B N   1 
ATOM   4504  C CA  . GLY B 1 195 ? 21.336  -34.871 14.475  1.00 57.61  ? 195 GLY B CA  1 
ATOM   4505  C C   . GLY B 1 195 ? 22.592  -34.653 13.656  1.00 59.02  ? 195 GLY B C   1 
ATOM   4506  O O   . GLY B 1 195 ? 22.724  -35.132 12.528  1.00 62.88  ? 195 GLY B O   1 
ATOM   4507  N N   . HIS B 1 196 ? 23.544  -33.932 14.260  1.00 56.59  ? 196 HIS B N   1 
ATOM   4508  C CA  . HIS B 1 196 ? 24.728  -33.399 13.578  1.00 62.34  ? 196 HIS B CA  1 
ATOM   4509  C C   . HIS B 1 196 ? 24.273  -32.266 12.660  1.00 58.52  ? 196 HIS B C   1 
ATOM   4510  O O   . HIS B 1 196 ? 24.000  -32.470 11.472  1.00 65.93  ? 196 HIS B O   1 
ATOM   4511  C CB  . HIS B 1 196 ? 25.499  -34.487 12.810  1.00 61.33  ? 196 HIS B CB  1 
ATOM   4512  C CG  . HIS B 1 196 ? 26.362  -35.355 13.679  1.00 66.37  ? 196 HIS B CG  1 
ATOM   4513  N ND1 . HIS B 1 196 ? 25.844  -36.316 14.523  1.00 68.79  ? 196 HIS B ND1 1 
ATOM   4514  C CD2 . HIS B 1 196 ? 27.708  -35.414 13.825  1.00 69.99  ? 196 HIS B CD2 1 
ATOM   4515  C CE1 . HIS B 1 196 ? 26.832  -36.928 15.152  1.00 71.99  ? 196 HIS B CE1 1 
ATOM   4516  N NE2 . HIS B 1 196 ? 27.974  -36.398 14.749  1.00 74.38  ? 196 HIS B NE2 1 
ATOM   4517  N N   . GLY B 1 197 ? 24.206  -31.064 13.214  1.00 50.40  ? 197 GLY B N   1 
ATOM   4518  C CA  . GLY B 1 197 ? 23.275  -30.046 12.767  1.00 47.48  ? 197 GLY B CA  1 
ATOM   4519  C C   . GLY B 1 197 ? 22.263  -29.675 13.830  1.00 39.50  ? 197 GLY B C   1 
ATOM   4520  O O   . GLY B 1 197 ? 21.551  -28.676 13.677  1.00 33.78  ? 197 GLY B O   1 
ATOM   4521  N N   . ASN B 1 198 ? 22.167  -30.441 14.909  1.00 39.53  ? 198 ASN B N   1 
ATOM   4522  C CA  . ASN B 1 198 ? 21.365  -30.062 16.060  1.00 34.95  ? 198 ASN B CA  1 
ATOM   4523  C C   . ASN B 1 198 ? 22.249  -30.019 17.301  1.00 34.47  ? 198 ASN B C   1 
ATOM   4524  O O   . ASN B 1 198 ? 23.035  -30.939 17.549  1.00 37.48  ? 198 ASN B O   1 
ATOM   4525  C CB  . ASN B 1 198 ? 20.193  -31.020 16.245  1.00 38.21  ? 198 ASN B CB  1 
ATOM   4526  C CG  . ASN B 1 198 ? 19.349  -31.139 14.996  1.00 37.18  ? 198 ASN B CG  1 
ATOM   4527  O OD1 . ASN B 1 198 ? 19.138  -30.165 14.269  1.00 38.81  ? 198 ASN B OD1 1 
ATOM   4528  N ND2 . ASN B 1 198 ? 18.850  -32.330 14.746  1.00 44.22  ? 198 ASN B ND2 1 
ATOM   4529  N N   . ILE B 1 199 ? 22.128  -28.945 18.069  1.00 29.94  ? 199 ILE B N   1 
ATOM   4530  C CA  . ILE B 1 199 ? 22.998  -28.699 19.208  1.00 33.35  ? 199 ILE B CA  1 
ATOM   4531  C C   . ILE B 1 199 ? 22.136  -28.528 20.454  1.00 33.53  ? 199 ILE B C   1 
ATOM   4532  O O   . ILE B 1 199 ? 21.272  -27.643 20.506  1.00 33.42  ? 199 ILE B O   1 
ATOM   4533  C CB  . ILE B 1 199 ? 23.893  -27.475 18.960  1.00 30.84  ? 199 ILE B CB  1 
ATOM   4534  C CG1 . ILE B 1 199 ? 24.821  -27.762 17.776  1.00 31.08  ? 199 ILE B CG1 1 
ATOM   4535  C CG2 . ILE B 1 199 ? 24.685  -27.102 20.222  1.00 32.87  ? 199 ILE B CG2 1 
ATOM   4536  C CD1 . ILE B 1 199 ? 25.643  -26.590 17.346  1.00 28.12  ? 199 ILE B CD1 1 
ATOM   4537  N N   . GLY B 1 200 ? 22.363  -29.383 21.453  1.00 33.26  ? 200 GLY B N   1 
ATOM   4538  C CA  . GLY B 1 200 ? 21.689  -29.225 22.731  1.00 31.94  ? 200 GLY B CA  1 
ATOM   4539  C C   . GLY B 1 200 ? 22.381  -28.205 23.625  1.00 32.02  ? 200 GLY B C   1 
ATOM   4540  O O   . GLY B 1 200 ? 23.584  -27.988 23.553  1.00 35.63  ? 200 GLY B O   1 
ATOM   4541  N N   . ILE B 1 201 ? 21.593  -27.554 24.470  1.00 27.84  ? 201 ILE B N   1 
ATOM   4542  C CA  . ILE B 1 201 ? 22.087  -26.568 25.417  1.00 28.53  ? 201 ILE B CA  1 
ATOM   4543  C C   . ILE B 1 201 ? 21.445  -26.863 26.762  1.00 34.91  ? 201 ILE B C   1 
ATOM   4544  O O   . ILE B 1 201 ? 20.220  -27.003 26.851  1.00 29.26  ? 201 ILE B O   1 
ATOM   4545  C CB  . ILE B 1 201 ? 21.763  -25.132 24.981  1.00 27.48  ? 201 ILE B CB  1 
ATOM   4546  C CG1 . ILE B 1 201 ? 22.357  -24.852 23.605  1.00 32.41  ? 201 ILE B CG1 1 
ATOM   4547  C CG2 . ILE B 1 201 ? 22.295  -24.128 26.001  1.00 35.19  ? 201 ILE B CG2 1 
ATOM   4548  C CD1 . ILE B 1 201 ? 21.552  -23.845 22.864  1.00 36.39  ? 201 ILE B CD1 1 
ATOM   4549  N N   . SER B 1 202 ? 22.268  -26.915 27.809  1.00 35.52  ? 202 SER B N   1 
ATOM   4550  C CA  . SER B 1 202 ? 21.892  -27.548 29.061  1.00 36.55  ? 202 SER B CA  1 
ATOM   4551  C C   . SER B 1 202 ? 22.424  -26.766 30.250  1.00 34.82  ? 202 SER B C   1 
ATOM   4552  O O   . SER B 1 202 ? 23.594  -26.364 30.273  1.00 32.65  ? 202 SER B O   1 
ATOM   4553  C CB  . SER B 1 202 ? 22.441  -28.971 29.122  1.00 34.26  ? 202 SER B CB  1 
ATOM   4554  O OG  . SER B 1 202 ? 21.545  -29.795 29.819  1.00 43.56  ? 202 SER B OG  1 
ATOM   4555  N N   . THR B 1 203 ? 21.564  -26.571 31.249  1.00 37.01  ? 203 THR B N   1 
ATOM   4556  C CA  . THR B 1 203 ? 22.059  -26.048 32.515  1.00 38.91  ? 203 THR B CA  1 
ATOM   4557  C C   . THR B 1 203 ? 22.809  -27.123 33.299  1.00 38.78  ? 203 THR B C   1 
ATOM   4558  O O   . THR B 1 203 ? 23.825  -26.827 33.931  1.00 43.97  ? 203 THR B O   1 
ATOM   4559  C CB  . THR B 1 203 ? 20.912  -25.462 33.333  1.00 37.17  ? 203 THR B CB  1 
ATOM   4560  O OG1 . THR B 1 203 ? 19.789  -26.355 33.338  1.00 37.35  ? 203 THR B OG1 1 
ATOM   4561  C CG2 . THR B 1 203 ? 20.491  -24.173 32.711  1.00 40.02  ? 203 THR B CG2 1 
ATOM   4562  N N   . SER B 1 204 ? 22.356  -28.380 33.241  1.00 38.71  ? 204 SER B N   1 
ATOM   4563  C CA  . SER B 1 204 ? 23.094  -29.392 33.993  1.00 39.41  ? 204 SER B CA  1 
ATOM   4564  C C   . SER B 1 204 ? 23.980  -30.235 33.079  1.00 44.28  ? 204 SER B C   1 
ATOM   4565  O O   . SER B 1 204 ? 23.595  -30.542 31.946  1.00 43.06  ? 204 SER B O   1 
ATOM   4566  C CB  . SER B 1 204 ? 22.145  -30.323 34.751  1.00 41.49  ? 204 SER B CB  1 
ATOM   4567  O OG  . SER B 1 204 ? 22.721  -31.615 34.911  1.00 39.86  ? 204 SER B OG  1 
ATOM   4568  N N   . PRO B 1 205 ? 25.159  -30.636 33.565  1.00 46.04  ? 205 PRO B N   1 
ATOM   4569  C CA  . PRO B 1 205 ? 26.066  -31.448 32.739  1.00 42.68  ? 205 PRO B CA  1 
ATOM   4570  C C   . PRO B 1 205 ? 25.607  -32.888 32.495  1.00 46.82  ? 205 PRO B C   1 
ATOM   4571  O O   . PRO B 1 205 ? 26.196  -33.550 31.634  1.00 45.61  ? 205 PRO B O   1 
ATOM   4572  C CB  . PRO B 1 205 ? 27.376  -31.427 33.540  1.00 42.66  ? 205 PRO B CB  1 
ATOM   4573  C CG  . PRO B 1 205 ? 27.255  -30.247 34.464  1.00 42.94  ? 205 PRO B CG  1 
ATOM   4574  C CD  . PRO B 1 205 ? 25.807  -30.165 34.803  1.00 41.35  ? 205 PRO B CD  1 
ATOM   4575  N N   . GLU B 1 206 ? 24.598  -33.407 33.197  1.00 42.58  ? 206 GLU B N   1 
ATOM   4576  C CA  . GLU B 1 206 ? 24.282  -34.831 33.092  1.00 55.14  ? 206 GLU B CA  1 
ATOM   4577  C C   . GLU B 1 206 ? 23.012  -35.092 32.277  1.00 56.68  ? 206 GLU B C   1 
ATOM   4578  O O   . GLU B 1 206 ? 22.481  -36.208 32.297  1.00 57.32  ? 206 GLU B O   1 
ATOM   4579  C CB  . GLU B 1 206 ? 24.196  -35.469 34.491  1.00 54.35  ? 206 GLU B CB  1 
ATOM   4580  C CG  . GLU B 1 206 ? 24.169  -37.052 34.576  1.00 66.56  ? 206 GLU B CG  1 
ATOM   4581  C CD  . GLU B 1 206 ? 25.478  -37.783 34.178  1.00 68.41  ? 206 GLU B CD  1 
ATOM   4582  O OE1 . GLU B 1 206 ? 26.465  -37.109 33.804  1.00 66.54  ? 206 GLU B OE1 1 
ATOM   4583  O OE2 . GLU B 1 206 ? 25.508  -39.046 34.235  1.00 51.94  ? 206 GLU B OE2 1 
ATOM   4584  N N   . SER B 1 207 ? 22.527  -34.101 31.534  1.00 53.21  ? 207 SER B N   1 
ATOM   4585  C CA  . SER B 1 207 ? 21.437  -34.332 30.593  1.00 55.68  ? 207 SER B CA  1 
ATOM   4586  C C   . SER B 1 207 ? 21.991  -34.725 29.222  1.00 53.34  ? 207 SER B C   1 
ATOM   4587  O O   . SER B 1 207 ? 23.064  -34.271 28.816  1.00 54.84  ? 207 SER B O   1 
ATOM   4588  C CB  . SER B 1 207 ? 20.571  -33.089 30.480  1.00 55.06  ? 207 SER B CB  1 
ATOM   4589  O OG  . SER B 1 207 ? 21.398  -31.952 30.352  1.00 52.28  ? 207 SER B OG  1 
ATOM   4590  N N   . SER B 1 208 ? 21.233  -35.556 28.497  1.00 48.16  ? 208 SER B N   1 
ATOM   4591  C CA  . SER B 1 208 ? 21.813  -36.436 27.481  1.00 48.67  ? 208 SER B CA  1 
ATOM   4592  C C   . SER B 1 208 ? 21.695  -35.934 26.042  1.00 53.16  ? 208 SER B C   1 
ATOM   4593  O O   . SER B 1 208 ? 22.714  -35.834 25.349  1.00 56.83  ? 208 SER B O   1 
ATOM   4594  C CB  . SER B 1 208 ? 21.187  -37.827 27.611  1.00 54.38  ? 208 SER B CB  1 
ATOM   4595  O OG  . SER B 1 208 ? 21.745  -38.503 28.725  1.00 61.97  ? 208 SER B OG  1 
ATOM   4596  N N   . PHE B 1 209 ? 20.479  -35.670 25.556  1.00 44.68  ? 209 PHE B N   1 
ATOM   4597  C CA  . PHE B 1 209 ? 20.228  -35.258 24.167  1.00 47.77  ? 209 PHE B CA  1 
ATOM   4598  C C   . PHE B 1 209 ? 20.585  -36.316 23.128  1.00 48.92  ? 209 PHE B C   1 
ATOM   4599  O O   . PHE B 1 209 ? 21.534  -36.109 22.357  1.00 45.74  ? 209 PHE B O   1 
ATOM   4600  C CB  . PHE B 1 209 ? 21.014  -34.013 23.769  1.00 43.35  ? 209 PHE B CB  1 
ATOM   4601  C CG  . PHE B 1 209 ? 20.650  -32.785 24.509  1.00 39.18  ? 209 PHE B CG  1 
ATOM   4602  C CD1 . PHE B 1 209 ? 19.611  -31.992 24.075  1.00 38.54  ? 209 PHE B CD1 1 
ATOM   4603  C CD2 . PHE B 1 209 ? 21.395  -32.377 25.593  1.00 39.60  ? 209 PHE B CD2 1 
ATOM   4604  C CE1 . PHE B 1 209 ? 19.291  -30.830 24.736  1.00 34.57  ? 209 PHE B CE1 1 
ATOM   4605  C CE2 . PHE B 1 209 ? 21.084  -31.205 26.259  1.00 43.75  ? 209 PHE B CE2 1 
ATOM   4606  C CZ  . PHE B 1 209 ? 20.031  -30.433 25.828  1.00 34.26  ? 209 PHE B CZ  1 
ATOM   4607  N N   . PRO B 1 210 ? 19.846  -37.421 23.039  1.00 48.64  ? 210 PRO B N   1 
ATOM   4608  C CA  . PRO B 1 210 ? 20.144  -38.429 22.012  1.00 49.26  ? 210 PRO B CA  1 
ATOM   4609  C C   . PRO B 1 210 ? 20.254  -37.826 20.616  1.00 48.83  ? 210 PRO B C   1 
ATOM   4610  O O   . PRO B 1 210 ? 19.367  -37.108 20.154  1.00 45.20  ? 210 PRO B O   1 
ATOM   4611  C CB  . PRO B 1 210 ? 18.959  -39.391 22.110  1.00 47.35  ? 210 PRO B CB  1 
ATOM   4612  C CG  . PRO B 1 210 ? 18.473  -39.265 23.501  1.00 53.47  ? 210 PRO B CG  1 
ATOM   4613  C CD  . PRO B 1 210 ? 18.854  -37.898 24.016  1.00 49.63  ? 210 PRO B CD  1 
ATOM   4614  N N   . GLY B 1 211 ? 21.375  -38.107 19.952  1.00 50.82  ? 211 GLY B N   1 
ATOM   4615  C CA  . GLY B 1 211 ? 21.521  -37.809 18.543  1.00 49.35  ? 211 GLY B CA  1 
ATOM   4616  C C   . GLY B 1 211 ? 21.982  -36.413 18.180  1.00 51.31  ? 211 GLY B C   1 
ATOM   4617  O O   . GLY B 1 211 ? 22.074  -36.117 16.988  1.00 54.63  ? 211 GLY B O   1 
ATOM   4618  N N   . THR B 1 212 ? 22.291  -35.550 19.147  1.00 53.40  ? 212 THR B N   1 
ATOM   4619  C CA  . THR B 1 212 ? 22.774  -34.218 18.806  1.00 47.25  ? 212 THR B CA  1 
ATOM   4620  C C   . THR B 1 212 ? 24.245  -34.254 18.380  1.00 49.01  ? 212 THR B C   1 
ATOM   4621  O O   . THR B 1 212 ? 24.926  -35.279 18.460  1.00 46.24  ? 212 THR B O   1 
ATOM   4622  C CB  . THR B 1 212 ? 22.613  -33.257 19.981  1.00 45.05  ? 212 THR B CB  1 
ATOM   4623  O OG1 . THR B 1 212 ? 23.249  -33.808 21.139  1.00 49.67  ? 212 THR B OG1 1 
ATOM   4624  C CG2 . THR B 1 212 ? 21.144  -33.027 20.294  1.00 46.38  ? 212 THR B CG2 1 
ATOM   4625  N N   . ARG B 1 213 ? 24.725  -33.098 17.918  1.00 47.28  ? 213 ARG B N   1 
ATOM   4626  C CA  . ARG B 1 213 ? 26.114  -32.881 17.527  1.00 44.52  ? 213 ARG B CA  1 
ATOM   4627  C C   . ARG B 1 213 ? 26.974  -32.604 18.750  1.00 44.02  ? 213 ARG B C   1 
ATOM   4628  O O   . ARG B 1 213 ? 27.713  -33.474 19.225  1.00 48.89  ? 213 ARG B O   1 
ATOM   4629  C CB  . ARG B 1 213 ? 26.192  -31.705 16.552  1.00 44.14  ? 213 ARG B CB  1 
ATOM   4630  C CG  . ARG B 1 213 ? 27.502  -31.543 15.819  1.00 47.87  ? 213 ARG B CG  1 
ATOM   4631  C CD  . ARG B 1 213 ? 27.803  -30.080 15.524  1.00 43.34  ? 213 ARG B CD  1 
ATOM   4632  N NE  . ARG B 1 213 ? 27.267  -29.693 14.225  1.00 54.01  ? 213 ARG B NE  1 
ATOM   4633  C CZ  . ARG B 1 213 ? 27.093  -28.443 13.821  1.00 46.90  ? 213 ARG B CZ  1 
ATOM   4634  N NH1 . ARG B 1 213 ? 27.490  -27.421 14.555  1.00 42.01  ? 213 ARG B NH1 1 
ATOM   4635  N NH2 . ARG B 1 213 ? 26.517  -28.216 12.642  1.00 58.40  ? 213 ARG B NH2 1 
ATOM   4636  N N   . GLU B 1 214 ? 26.891  -31.380 19.250  1.00 44.63  ? 214 GLU B N   1 
ATOM   4637  C CA  . GLU B 1 214 ? 27.482  -30.973 20.516  1.00 42.90  ? 214 GLU B CA  1 
ATOM   4638  C C   . GLU B 1 214 ? 26.380  -30.822 21.556  1.00 40.05  ? 214 GLU B C   1 
ATOM   4639  O O   . GLU B 1 214 ? 25.187  -30.812 21.233  1.00 36.17  ? 214 GLU B O   1 
ATOM   4640  C CB  . GLU B 1 214 ? 28.241  -29.646 20.373  1.00 36.86  ? 214 GLU B CB  1 
ATOM   4641  C CG  . GLU B 1 214 ? 29.773  -29.750 20.333  1.00 48.71  ? 214 GLU B CG  1 
ATOM   4642  C CD  . GLU B 1 214 ? 30.315  -29.959 18.933  1.00 49.54  ? 214 GLU B CD  1 
ATOM   4643  O OE1 . GLU B 1 214 ? 31.370  -30.615 18.777  1.00 50.72  ? 214 GLU B OE1 1 
ATOM   4644  O OE2 . GLU B 1 214 ? 29.681  -29.455 17.986  1.00 50.96  ? 214 GLU B OE2 1 
ATOM   4645  N N   . VAL B 1 215 ? 26.801  -30.694 22.815  1.00 38.93  ? 215 VAL B N   1 
ATOM   4646  C CA  . VAL B 1 215 ? 25.946  -30.262 23.918  1.00 40.01  ? 215 VAL B CA  1 
ATOM   4647  C C   . VAL B 1 215 ? 26.699  -29.163 24.650  1.00 36.58  ? 215 VAL B C   1 
ATOM   4648  O O   . VAL B 1 215 ? 27.755  -29.417 25.234  1.00 40.45  ? 215 VAL B O   1 
ATOM   4649  C CB  . VAL B 1 215 ? 25.593  -31.407 24.876  1.00 37.16  ? 215 VAL B CB  1 
ATOM   4650  C CG1 . VAL B 1 215 ? 24.649  -30.909 25.974  1.00 33.18  ? 215 VAL B CG1 1 
ATOM   4651  C CG2 . VAL B 1 215 ? 24.973  -32.553 24.108  1.00 39.05  ? 215 VAL B CG2 1 
ATOM   4652  N N   . LEU B 1 216 ? 26.166  -27.953 24.628  1.00 34.22  ? 216 LEU B N   1 
ATOM   4653  C CA  . LEU B 1 216 ? 26.854  -26.809 25.199  1.00 33.70  ? 216 LEU B CA  1 
ATOM   4654  C C   . LEU B 1 216 ? 26.250  -26.440 26.547  1.00 32.60  ? 216 LEU B C   1 
ATOM   4655  O O   . LEU B 1 216 ? 25.099  -26.759 26.854  1.00 32.54  ? 216 LEU B O   1 
ATOM   4656  C CB  . LEU B 1 216 ? 26.799  -25.609 24.245  1.00 36.98  ? 216 LEU B CB  1 
ATOM   4657  C CG  . LEU B 1 216 ? 27.186  -25.913 22.790  1.00 33.76  ? 216 LEU B CG  1 
ATOM   4658  C CD1 . LEU B 1 216 ? 27.188  -24.666 21.907  1.00 27.01  ? 216 LEU B CD1 1 
ATOM   4659  C CD2 . LEU B 1 216 ? 28.529  -26.589 22.735  1.00 35.18  ? 216 LEU B CD2 1 
ATOM   4660  N N   . ALA B 1 217 ? 27.052  -25.753 27.347  1.00 36.06  ? 217 ALA B N   1 
ATOM   4661  C CA  . ALA B 1 217 ? 26.630  -25.319 28.669  1.00 36.69  ? 217 ALA B CA  1 
ATOM   4662  C C   . ALA B 1 217 ? 25.860  -24.007 28.586  1.00 36.85  ? 217 ALA B C   1 
ATOM   4663  O O   . ALA B 1 217 ? 26.238  -23.086 27.854  1.00 39.77  ? 217 ALA B O   1 
ATOM   4664  C CB  . ALA B 1 217 ? 27.848  -25.159 29.589  1.00 32.58  ? 217 ALA B CB  1 
ATOM   4665  N N   . TYR B 1 218 ? 24.774  -23.923 29.347  1.00 40.24  ? 218 TYR B N   1 
ATOM   4666  C CA  . TYR B 1 218 ? 24.044  -22.671 29.519  1.00 45.09  ? 218 TYR B CA  1 
ATOM   4667  C C   . TYR B 1 218 ? 24.607  -21.937 30.734  1.00 48.75  ? 218 TYR B C   1 
ATOM   4668  O O   . TYR B 1 218 ? 24.432  -22.376 31.878  1.00 44.73  ? 218 TYR B O   1 
ATOM   4669  C CB  . TYR B 1 218 ? 22.547  -22.915 29.693  1.00 40.04  ? 218 TYR B CB  1 
ATOM   4670  C CG  . TYR B 1 218 ? 21.786  -21.628 29.962  1.00 47.14  ? 218 TYR B CG  1 
ATOM   4671  C CD1 . TYR B 1 218 ? 21.293  -20.865 28.913  1.00 39.48  ? 218 TYR B CD1 1 
ATOM   4672  C CD2 . TYR B 1 218 ? 21.580  -21.167 31.264  1.00 43.98  ? 218 TYR B CD2 1 
ATOM   4673  C CE1 . TYR B 1 218 ? 20.614  -19.685 29.147  1.00 46.66  ? 218 TYR B CE1 1 
ATOM   4674  C CE2 . TYR B 1 218 ? 20.904  -19.982 31.503  1.00 47.18  ? 218 TYR B CE2 1 
ATOM   4675  C CZ  . TYR B 1 218 ? 20.424  -19.249 30.441  1.00 46.17  ? 218 TYR B CZ  1 
ATOM   4676  O OH  . TYR B 1 218 ? 19.747  -18.079 30.663  1.00 52.27  ? 218 TYR B OH  1 
ATOM   4677  N N   . ALA B 1 219 ? 25.274  -20.816 30.486  1.00 50.87  ? 219 ALA B N   1 
ATOM   4678  C CA  . ALA B 1 219 ? 25.720  -19.922 31.544  1.00 56.00  ? 219 ALA B CA  1 
ATOM   4679  C C   . ALA B 1 219 ? 25.408  -18.509 31.083  1.00 58.68  ? 219 ALA B C   1 
ATOM   4680  O O   . ALA B 1 219 ? 25.888  -18.086 30.027  1.00 55.58  ? 219 ALA B O   1 
ATOM   4681  C CB  . ALA B 1 219 ? 27.212  -20.101 31.835  1.00 57.53  ? 219 ALA B CB  1 
ATOM   4682  N N   . ASN B 1 220 ? 24.593  -17.794 31.866  1.00 59.78  ? 220 ASN B N   1 
ATOM   4683  C CA  . ASN B 1 220 ? 24.012  -16.538 31.393  1.00 60.64  ? 220 ASN B CA  1 
ATOM   4684  C C   . ASN B 1 220 ? 25.080  -15.524 31.014  1.00 60.25  ? 220 ASN B C   1 
ATOM   4685  O O   . ASN B 1 220 ? 24.925  -14.785 30.037  1.00 60.98  ? 220 ASN B O   1 
ATOM   4686  C CB  . ASN B 1 220 ? 23.085  -15.960 32.458  1.00 62.92  ? 220 ASN B CB  1 
ATOM   4687  C CG  . ASN B 1 220 ? 21.723  -15.621 31.911  1.00 64.34  ? 220 ASN B CG  1 
ATOM   4688  O OD1 . ASN B 1 220 ? 21.606  -14.986 30.859  1.00 62.30  ? 220 ASN B OD1 1 
ATOM   4689  N ND2 . ASN B 1 220 ? 20.676  -16.058 32.611  1.00 66.45  ? 220 ASN B ND2 1 
ATOM   4690  N N   . ASP B 1 221 ? 26.173  -15.484 31.766  1.00 64.36  ? 221 ASP B N   1 
ATOM   4691  C CA  . ASP B 1 221 ? 27.254  -14.537 31.532  1.00 64.14  ? 221 ASP B CA  1 
ATOM   4692  C C   . ASP B 1 221 ? 27.973  -14.757 30.202  1.00 62.28  ? 221 ASP B C   1 
ATOM   4693  O O   . ASP B 1 221 ? 28.847  -13.956 29.851  1.00 60.35  ? 221 ASP B O   1 
ATOM   4694  C CB  . ASP B 1 221 ? 28.248  -14.625 32.694  1.00 70.99  ? 221 ASP B CB  1 
ATOM   4695  C CG  . ASP B 1 221 ? 27.588  -15.078 34.001  1.00 75.21  ? 221 ASP B CG  1 
ATOM   4696  O OD1 . ASP B 1 221 ? 26.817  -16.069 33.982  1.00 69.20  ? 221 ASP B OD1 1 
ATOM   4697  O OD2 . ASP B 1 221 ? 27.843  -14.442 35.050  1.00 75.63  ? 221 ASP B OD2 1 
ATOM   4698  N N   . GLN B 1 222 ? 27.631  -15.815 29.461  1.00 63.45  ? 222 GLN B N   1 
ATOM   4699  C CA  . GLN B 1 222 ? 28.291  -16.157 28.206  1.00 59.29  ? 222 GLN B CA  1 
ATOM   4700  C C   . GLN B 1 222 ? 27.296  -16.337 27.066  1.00 58.72  ? 222 GLN B C   1 
ATOM   4701  O O   . GLN B 1 222 ? 27.678  -16.830 25.994  1.00 55.91  ? 222 GLN B O   1 
ATOM   4702  C CB  . GLN B 1 222 ? 29.126  -17.436 28.365  1.00 57.62  ? 222 GLN B CB  1 
ATOM   4703  C CG  . GLN B 1 222 ? 30.629  -17.216 28.299  1.00 61.42  ? 222 GLN B CG  1 
ATOM   4704  C CD  . GLN B 1 222 ? 31.355  -18.393 27.679  1.00 72.56  ? 222 GLN B CD  1 
ATOM   4705  O OE1 . GLN B 1 222 ? 31.207  -19.536 28.120  1.00 74.96  ? 222 GLN B OE1 1 
ATOM   4706  N NE2 . GLN B 1 222 ? 32.137  -18.122 26.637  1.00 73.16  ? 222 GLN B NE2 1 
ATOM   4707  N N   . LEU B 1 223 ? 26.038  -15.937 27.268  1.00 55.41  ? 223 LEU B N   1 
ATOM   4708  C CA  . LEU B 1 223 ? 24.990  -16.210 26.291  1.00 53.42  ? 223 LEU B CA  1 
ATOM   4709  C C   . LEU B 1 223 ? 25.214  -15.459 24.984  1.00 52.74  ? 223 LEU B C   1 
ATOM   4710  O O   . LEU B 1 223 ? 25.005  -16.020 23.901  1.00 52.83  ? 223 LEU B O   1 
ATOM   4711  C CB  . LEU B 1 223 ? 23.634  -15.845 26.876  1.00 53.01  ? 223 LEU B CB  1 
ATOM   4712  C CG  . LEU B 1 223 ? 22.581  -16.918 26.682  1.00 48.90  ? 223 LEU B CG  1 
ATOM   4713  C CD1 . LEU B 1 223 ? 23.139  -18.222 27.182  1.00 49.94  ? 223 LEU B CD1 1 
ATOM   4714  C CD2 . LEU B 1 223 ? 21.329  -16.541 27.431  1.00 50.31  ? 223 LEU B CD2 1 
ATOM   4715  N N   . ASP B 1 224 ? 25.603  -14.182 25.068  1.00 54.25  ? 224 ASP B N   1 
ATOM   4716  C CA  . ASP B 1 224 ? 25.848  -13.384 23.869  1.00 53.34  ? 224 ASP B CA  1 
ATOM   4717  C C   . ASP B 1 224 ? 26.715  -14.148 22.889  1.00 50.12  ? 224 ASP B C   1 
ATOM   4718  O O   . ASP B 1 224 ? 26.431  -14.193 21.686  1.00 46.77  ? 224 ASP B O   1 
ATOM   4719  C CB  . ASP B 1 224 ? 26.540  -12.058 24.223  1.00 58.75  ? 224 ASP B CB  1 
ATOM   4720  C CG  . ASP B 1 224 ? 25.806  -11.259 25.278  1.00 61.38  ? 224 ASP B CG  1 
ATOM   4721  O OD1 . ASP B 1 224 ? 24.798  -11.756 25.826  1.00 64.64  ? 224 ASP B OD1 1 
ATOM   4722  O OD2 . ASP B 1 224 ? 26.256  -10.127 25.567  1.00 67.76  ? 224 ASP B OD2 1 
ATOM   4723  N N   . THR B 1 225 ? 27.790  -14.751 23.404  1.00 47.82  ? 225 THR B N   1 
ATOM   4724  C CA  . THR B 1 225 ? 28.715  -15.496 22.562  1.00 49.02  ? 225 THR B CA  1 
ATOM   4725  C C   . THR B 1 225 ? 28.089  -16.797 22.083  1.00 45.86  ? 225 THR B C   1 
ATOM   4726  O O   . THR B 1 225 ? 28.282  -17.198 20.926  1.00 41.99  ? 225 THR B O   1 
ATOM   4727  C CB  . THR B 1 225 ? 30.013  -15.760 23.332  1.00 51.75  ? 225 THR B CB  1 
ATOM   4728  O OG1 . THR B 1 225 ? 30.800  -14.563 23.343  1.00 58.31  ? 225 THR B OG1 1 
ATOM   4729  C CG2 . THR B 1 225 ? 30.818  -16.885 22.697  1.00 47.11  ? 225 THR B CG2 1 
ATOM   4730  N N   . LEU B 1 226 ? 27.337  -17.466 22.959  1.00 48.93  ? 226 LEU B N   1 
ATOM   4731  C CA  . LEU B 1 226 ? 26.638  -18.681 22.558  1.00 48.29  ? 226 LEU B CA  1 
ATOM   4732  C C   . LEU B 1 226 ? 25.765  -18.430 21.330  1.00 44.54  ? 226 LEU B C   1 
ATOM   4733  O O   . LEU B 1 226 ? 25.927  -19.090 20.293  1.00 34.91  ? 226 LEU B O   1 
ATOM   4734  C CB  . LEU B 1 226 ? 25.801  -19.205 23.723  1.00 42.29  ? 226 LEU B CB  1 
ATOM   4735  C CG  . LEU B 1 226 ? 25.354  -20.653 23.537  1.00 46.75  ? 226 LEU B CG  1 
ATOM   4736  C CD1 . LEU B 1 226 ? 26.409  -21.413 22.787  1.00 44.47  ? 226 LEU B CD1 1 
ATOM   4737  C CD2 . LEU B 1 226 ? 25.094  -21.319 24.869  1.00 47.15  ? 226 LEU B CD2 1 
ATOM   4738  N N   . ALA B 1 227 ? 24.861  -17.443 21.419  1.00 40.48  ? 227 ALA B N   1 
ATOM   4739  C CA  . ALA B 1 227 ? 23.923  -17.185 20.330  1.00 36.96  ? 227 ALA B CA  1 
ATOM   4740  C C   . ALA B 1 227 ? 24.650  -16.800 19.050  1.00 39.45  ? 227 ALA B C   1 
ATOM   4741  O O   . ALA B 1 227 ? 24.305  -17.291 17.969  1.00 36.06  ? 227 ALA B O   1 
ATOM   4742  C CB  . ALA B 1 227 ? 22.932  -16.093 20.732  1.00 35.02  ? 227 ALA B CB  1 
ATOM   4743  N N   . ASP B 1 228 ? 25.676  -15.943 19.161  1.00 36.36  ? 228 ASP B N   1 
ATOM   4744  C CA  . ASP B 1 228 ? 26.432  -15.480 17.995  1.00 39.55  ? 228 ASP B CA  1 
ATOM   4745  C C   . ASP B 1 228 ? 27.057  -16.648 17.242  1.00 41.70  ? 228 ASP B C   1 
ATOM   4746  O O   . ASP B 1 228 ? 26.987  -16.727 16.007  1.00 36.72  ? 228 ASP B O   1 
ATOM   4747  C CB  . ASP B 1 228 ? 27.528  -14.504 18.442  1.00 39.66  ? 228 ASP B CB  1 
ATOM   4748  C CG  . ASP B 1 228 ? 27.075  -13.049 18.450  1.00 53.22  ? 228 ASP B CG  1 
ATOM   4749  O OD1 . ASP B 1 228 ? 25.852  -12.779 18.379  1.00 52.53  ? 228 ASP B OD1 1 
ATOM   4750  O OD2 . ASP B 1 228 ? 27.958  -12.164 18.544  1.00 61.32  ? 228 ASP B OD2 1 
ATOM   4751  N N   . THR B 1 229 ? 27.701  -17.555 17.980  1.00 35.40  ? 229 THR B N   1 
ATOM   4752  C CA  . THR B 1 229 ? 28.377  -18.684 17.366  1.00 37.85  ? 229 THR B CA  1 
ATOM   4753  C C   . THR B 1 229 ? 27.385  -19.777 16.979  1.00 35.02  ? 229 THR B C   1 
ATOM   4754  O O   . THR B 1 229 ? 27.544  -20.412 15.933  1.00 33.97  ? 229 THR B O   1 
ATOM   4755  C CB  . THR B 1 229 ? 29.460  -19.226 18.310  1.00 43.05  ? 229 THR B CB  1 
ATOM   4756  O OG1 . THR B 1 229 ? 30.146  -18.134 18.932  1.00 42.74  ? 229 THR B OG1 1 
ATOM   4757  C CG2 . THR B 1 229 ? 30.485  -20.026 17.542  1.00 42.74  ? 229 THR B CG2 1 
ATOM   4758  N N   . LEU B 1 230 ? 26.343  -19.999 17.786  1.00 36.30  ? 230 LEU B N   1 
ATOM   4759  C CA  . LEU B 1 230 ? 25.311  -20.950 17.377  1.00 37.59  ? 230 LEU B CA  1 
ATOM   4760  C C   . LEU B 1 230 ? 24.702  -20.553 16.040  1.00 32.53  ? 230 LEU B C   1 
ATOM   4761  O O   . LEU B 1 230 ? 24.488  -21.402 15.169  1.00 28.91  ? 230 LEU B O   1 
ATOM   4762  C CB  . LEU B 1 230 ? 24.224  -21.052 18.441  1.00 33.72  ? 230 LEU B CB  1 
ATOM   4763  C CG  . LEU B 1 230 ? 24.471  -22.115 19.504  1.00 40.33  ? 230 LEU B CG  1 
ATOM   4764  C CD1 . LEU B 1 230 ? 23.292  -22.167 20.434  1.00 32.86  ? 230 LEU B CD1 1 
ATOM   4765  C CD2 . LEU B 1 230 ? 24.735  -23.481 18.861  1.00 31.13  ? 230 LEU B CD2 1 
ATOM   4766  N N   . TRP B 1 231 ? 24.428  -19.263 15.859  1.00 28.15  ? 231 TRP B N   1 
ATOM   4767  C CA  . TRP B 1 231 ? 23.899  -18.799 14.586  1.00 32.12  ? 231 TRP B CA  1 
ATOM   4768  C C   . TRP B 1 231 ? 24.875  -19.097 13.456  1.00 36.83  ? 231 TRP B C   1 
ATOM   4769  O O   . TRP B 1 231 ? 24.478  -19.586 12.395  1.00 31.95  ? 231 TRP B O   1 
ATOM   4770  C CB  . TRP B 1 231 ? 23.599  -17.309 14.675  1.00 32.33  ? 231 TRP B CB  1 
ATOM   4771  C CG  . TRP B 1 231 ? 23.093  -16.705 13.415  1.00 35.90  ? 231 TRP B CG  1 
ATOM   4772  C CD1 . TRP B 1 231 ? 23.802  -15.947 12.535  1.00 37.18  ? 231 TRP B CD1 1 
ATOM   4773  C CD2 . TRP B 1 231 ? 21.750  -16.766 12.905  1.00 31.91  ? 231 TRP B CD2 1 
ATOM   4774  N NE1 . TRP B 1 231 ? 22.994  -15.547 11.492  1.00 36.63  ? 231 TRP B NE1 1 
ATOM   4775  C CE2 . TRP B 1 231 ? 21.729  -16.038 11.697  1.00 35.64  ? 231 TRP B CE2 1 
ATOM   4776  C CE3 . TRP B 1 231 ? 20.565  -17.359 13.352  1.00 29.80  ? 231 TRP B CE3 1 
ATOM   4777  C CZ2 . TRP B 1 231 ? 20.566  -15.889 10.929  1.00 33.73  ? 231 TRP B CZ2 1 
ATOM   4778  C CZ3 . TRP B 1 231 ? 19.410  -17.225 12.572  1.00 24.51  ? 231 TRP B CZ3 1 
ATOM   4779  C CH2 . TRP B 1 231 ? 19.423  -16.495 11.385  1.00 29.39  ? 231 TRP B CH2 1 
ATOM   4780  N N   . SER B 1 232 ? 26.168  -18.858 13.693  1.00 35.34  ? 232 SER B N   1 
ATOM   4781  C CA  . SER B 1 232 ? 27.173  -19.022 12.646  1.00 39.12  ? 232 SER B CA  1 
ATOM   4782  C C   . SER B 1 232 ? 27.370  -20.489 12.275  1.00 36.40  ? 232 SER B C   1 
ATOM   4783  O O   . SER B 1 232 ? 27.557  -20.817 11.096  1.00 33.58  ? 232 SER B O   1 
ATOM   4784  C CB  . SER B 1 232 ? 28.490  -18.392 13.102  1.00 40.55  ? 232 SER B CB  1 
ATOM   4785  O OG  . SER B 1 232 ? 28.904  -18.946 14.346  1.00 39.69  ? 232 SER B OG  1 
ATOM   4786  N N   . GLN B 1 233 ? 27.310  -21.387 13.261  1.00 36.41  ? 233 GLN B N   1 
ATOM   4787  C CA  . GLN B 1 233 ? 27.340  -22.821 12.976  1.00 37.24  ? 233 GLN B CA  1 
ATOM   4788  C C   . GLN B 1 233 ? 26.164  -23.256 12.107  1.00 38.45  ? 233 GLN B C   1 
ATOM   4789  O O   . GLN B 1 233 ? 26.350  -23.922 11.081  1.00 44.58  ? 233 GLN B O   1 
ATOM   4790  C CB  . GLN B 1 233 ? 27.314  -23.617 14.277  1.00 40.27  ? 233 GLN B CB  1 
ATOM   4791  C CG  . GLN B 1 233 ? 28.419  -23.316 15.232  1.00 44.65  ? 233 GLN B CG  1 
ATOM   4792  C CD  . GLN B 1 233 ? 29.356  -24.475 15.335  1.00 44.18  ? 233 GLN B CD  1 
ATOM   4793  O OE1 . GLN B 1 233 ? 28.918  -25.629 15.353  1.00 43.71  ? 233 GLN B OE1 1 
ATOM   4794  N NE2 . GLN B 1 233 ? 30.650  -24.190 15.439  1.00 42.64  ? 233 GLN B NE2 1 
ATOM   4795  N N   . LEU B 1 234 ? 24.941  -22.917 12.515  1.00 29.16  ? 234 LEU B N   1 
ATOM   4796  C CA  . LEU B 1 234 ? 23.774  -23.616 11.995  1.00 29.70  ? 234 LEU B CA  1 
ATOM   4797  C C   . LEU B 1 234 ? 23.113  -22.929 10.799  1.00 30.14  ? 234 LEU B C   1 
ATOM   4798  O O   . LEU B 1 234 ? 22.117  -23.440 10.292  1.00 31.76  ? 234 LEU B O   1 
ATOM   4799  C CB  . LEU B 1 234 ? 22.757  -23.820 13.117  1.00 28.78  ? 234 LEU B CB  1 
ATOM   4800  C CG  . LEU B 1 234 ? 23.187  -24.603 14.354  1.00 30.34  ? 234 LEU B CG  1 
ATOM   4801  C CD1 . LEU B 1 234 ? 22.120  -24.541 15.437  1.00 32.51  ? 234 LEU B CD1 1 
ATOM   4802  C CD2 . LEU B 1 234 ? 23.475  -26.050 14.007  1.00 35.05  ? 234 LEU B CD2 1 
ATOM   4803  N N   . THR B 1 235 ? 23.631  -21.808 10.319  1.00 32.37  ? 235 THR B N   1 
ATOM   4804  C CA  . THR B 1 235 ? 23.065  -21.174 9.136   1.00 34.62  ? 235 THR B CA  1 
ATOM   4805  C C   . THR B 1 235 ? 24.016  -21.341 7.962   1.00 35.17  ? 235 THR B C   1 
ATOM   4806  O O   . THR B 1 235 ? 25.183  -21.710 8.122   1.00 34.24  ? 235 THR B O   1 
ATOM   4807  C CB  . THR B 1 235 ? 22.782  -19.678 9.367   1.00 29.93  ? 235 THR B CB  1 
ATOM   4808  O OG1 . THR B 1 235 ? 23.958  -19.016 9.835   1.00 36.38  ? 235 THR B OG1 1 
ATOM   4809  C CG2 . THR B 1 235 ? 21.652  -19.465 10.362  1.00 31.04  ? 235 THR B CG2 1 
ATOM   4810  N N   . ASP B 1 236 ? 23.501  -21.062 6.770   1.00 39.09  ? 236 ASP B N   1 
ATOM   4811  C CA  . ASP B 1 236 ? 24.334  -20.880 5.580   1.00 37.12  ? 236 ASP B CA  1 
ATOM   4812  C C   . ASP B 1 236 ? 23.622  -19.883 4.674   1.00 39.31  ? 236 ASP B C   1 
ATOM   4813  O O   . ASP B 1 236 ? 22.632  -19.259 5.076   1.00 37.35  ? 236 ASP B O   1 
ATOM   4814  C CB  . ASP B 1 236 ? 24.621  -22.224 4.896   1.00 37.28  ? 236 ASP B CB  1 
ATOM   4815  C CG  . ASP B 1 236 ? 23.353  -22.937 4.444   1.00 44.35  ? 236 ASP B CG  1 
ATOM   4816  O OD1 . ASP B 1 236 ? 22.383  -22.263 4.024   1.00 45.10  ? 236 ASP B OD1 1 
ATOM   4817  O OD2 . ASP B 1 236 ? 23.306  -24.176 4.529   1.00 41.59  ? 236 ASP B OD2 1 
ATOM   4818  N N   . THR B 1 237 ? 24.113  -19.756 3.436   1.00 41.62  ? 237 THR B N   1 
ATOM   4819  C CA  . THR B 1 237 ? 23.581  -18.755 2.516   1.00 38.28  ? 237 THR B CA  1 
ATOM   4820  C C   . THR B 1 237 ? 22.084  -18.954 2.273   1.00 36.21  ? 237 THR B C   1 
ATOM   4821  O O   . THR B 1 237 ? 21.321  -17.982 2.244   1.00 30.28  ? 237 THR B O   1 
ATOM   4822  C CB  . THR B 1 237 ? 24.382  -18.780 1.201   1.00 38.41  ? 237 THR B CB  1 
ATOM   4823  O OG1 . THR B 1 237 ? 25.588  -18.012 1.356   1.00 46.45  ? 237 THR B OG1 1 
ATOM   4824  C CG2 . THR B 1 237 ? 23.609  -18.185 0.059   1.00 31.73  ? 237 THR B CG2 1 
ATOM   4825  N N   . GLN B 1 238 ? 21.637  -20.202 2.125   1.00 37.44  ? 238 GLN B N   1 
ATOM   4826  C CA  . GLN B 1 238 ? 20.234  -20.483 1.835   1.00 37.75  ? 238 GLN B CA  1 
ATOM   4827  C C   . GLN B 1 238 ? 19.404  -20.782 3.083   1.00 36.16  ? 238 GLN B C   1 
ATOM   4828  O O   . GLN B 1 238 ? 18.185  -20.927 2.967   1.00 33.67  ? 238 GLN B O   1 
ATOM   4829  C CB  . GLN B 1 238 ? 20.119  -21.662 0.854   1.00 41.95  ? 238 GLN B CB  1 
ATOM   4830  C CG  . GLN B 1 238 ? 21.150  -21.677 -0.292  1.00 46.41  ? 238 GLN B CG  1 
ATOM   4831  C CD  . GLN B 1 238 ? 22.472  -22.351 0.091   1.00 47.18  ? 238 GLN B CD  1 
ATOM   4832  O OE1 . GLN B 1 238 ? 22.492  -23.330 0.840   1.00 46.35  ? 238 GLN B OE1 1 
ATOM   4833  N NE2 . GLN B 1 238 ? 23.578  -21.818 -0.421  1.00 42.79  ? 238 GLN B NE2 1 
ATOM   4834  N N   . ASN B 1 239 ? 20.033  -20.881 4.255   1.00 35.93  ? 239 ASN B N   1 
ATOM   4835  C CA  . ASN B 1 239 ? 19.401  -21.196 5.543   1.00 37.92  ? 239 ASN B CA  1 
ATOM   4836  C C   . ASN B 1 239 ? 19.572  -20.017 6.490   1.00 36.61  ? 239 ASN B C   1 
ATOM   4837  O O   . ASN B 1 239 ? 20.500  -20.022 7.305   1.00 35.76  ? 239 ASN B O   1 
ATOM   4838  C CB  . ASN B 1 239 ? 20.039  -22.417 6.198   1.00 42.28  ? 239 ASN B CB  1 
ATOM   4839  C CG  . ASN B 1 239 ? 19.486  -23.711 5.710   1.00 44.18  ? 239 ASN B CG  1 
ATOM   4840  O OD1 . ASN B 1 239 ? 19.504  -24.712 6.444   1.00 47.82  ? 239 ASN B OD1 1 
ATOM   4841  N ND2 . ASN B 1 239 ? 19.017  -23.729 4.470   1.00 39.71  ? 239 ASN B ND2 1 
ATOM   4842  N N   . GLN B 1 240 ? 18.677  -19.031 6.421   1.00 31.70  ? 240 GLN B N   1 
ATOM   4843  C CA  . GLN B 1 240 ? 18.718  -17.901 7.338   1.00 22.61  ? 240 GLN B CA  1 
ATOM   4844  C C   . GLN B 1 240 ? 17.721  -18.056 8.472   1.00 31.26  ? 240 GLN B C   1 
ATOM   4845  O O   . GLN B 1 240 ? 17.286  -17.050 9.045   1.00 31.96  ? 240 GLN B O   1 
ATOM   4846  C CB  . GLN B 1 240 ? 18.457  -16.588 6.595   1.00 34.27  ? 240 GLN B CB  1 
ATOM   4847  C CG  . GLN B 1 240 ? 19.659  -15.962 5.856   1.00 39.29  ? 240 GLN B CG  1 
ATOM   4848  C CD  . GLN B 1 240 ? 20.943  -15.919 6.675   1.00 36.30  ? 240 GLN B CD  1 
ATOM   4849  O OE1 . GLN B 1 240 ? 21.712  -16.878 6.701   1.00 41.05  ? 240 GLN B OE1 1 
ATOM   4850  N NE2 . GLN B 1 240 ? 21.176  -14.806 7.345   1.00 30.60  ? 240 GLN B NE2 1 
ATOM   4851  N N   . PHE B 1 241 ? 17.318  -19.292 8.778   1.00 32.13  ? 241 PHE B N   1 
ATOM   4852  C CA  . PHE B 1 241 ? 16.518  -19.604 9.956   1.00 28.70  ? 241 PHE B CA  1 
ATOM   4853  C C   . PHE B 1 241 ? 17.260  -20.626 10.802  1.00 30.94  ? 241 PHE B C   1 
ATOM   4854  O O   . PHE B 1 241 ? 17.933  -21.521 10.273  1.00 27.41  ? 241 PHE B O   1 
ATOM   4855  C CB  . PHE B 1 241 ? 15.141  -20.231 9.630   1.00 27.24  ? 241 PHE B CB  1 
ATOM   4856  C CG  . PHE B 1 241 ? 14.177  -19.327 8.900   1.00 30.42  ? 241 PHE B CG  1 
ATOM   4857  C CD1 . PHE B 1 241 ? 14.169  -17.958 9.103   1.00 29.17  ? 241 PHE B CD1 1 
ATOM   4858  C CD2 . PHE B 1 241 ? 13.261  -19.878 8.008   1.00 31.60  ? 241 PHE B CD2 1 
ATOM   4859  C CE1 . PHE B 1 241 ? 13.272  -17.153 8.432   1.00 32.16  ? 241 PHE B CE1 1 
ATOM   4860  C CE2 . PHE B 1 241 ? 12.354  -19.082 7.330   1.00 30.70  ? 241 PHE B CE2 1 
ATOM   4861  C CZ  . PHE B 1 241 ? 12.357  -17.717 7.543   1.00 34.68  ? 241 PHE B CZ  1 
ATOM   4862  N N   . ILE B 1 242 ? 17.088  -20.489 12.113  1.00 26.10  ? 242 ILE B N   1 
ATOM   4863  C CA  . ILE B 1 242 ? 17.392  -21.502 13.109  1.00 25.10  ? 242 ILE B CA  1 
ATOM   4864  C C   . ILE B 1 242 ? 16.106  -21.820 13.844  1.00 26.18  ? 242 ILE B C   1 
ATOM   4865  O O   . ILE B 1 242 ? 15.281  -20.929 14.068  1.00 29.34  ? 242 ILE B O   1 
ATOM   4866  C CB  . ILE B 1 242 ? 18.470  -21.013 14.104  1.00 31.66  ? 242 ILE B CB  1 
ATOM   4867  C CG1 . ILE B 1 242 ? 19.749  -20.694 13.355  1.00 35.50  ? 242 ILE B CG1 1 
ATOM   4868  C CG2 . ILE B 1 242 ? 18.757  -22.047 15.186  1.00 29.38  ? 242 ILE B CG2 1 
ATOM   4869  C CD1 . ILE B 1 242 ? 20.137  -21.813 12.443  1.00 33.23  ? 242 ILE B CD1 1 
ATOM   4870  N N   . THR B 1 243 ? 15.943  -23.076 14.231  1.00 22.51  ? 243 THR B N   1 
ATOM   4871  C CA  . THR B 1 243 ? 14.902  -23.463 15.160  1.00 26.10  ? 243 THR B CA  1 
ATOM   4872  C C   . THR B 1 243 ? 15.538  -23.592 16.544  1.00 31.01  ? 243 THR B C   1 
ATOM   4873  O O   . THR B 1 243 ? 16.683  -24.034 16.669  1.00 29.16  ? 243 THR B O   1 
ATOM   4874  C CB  . THR B 1 243 ? 14.231  -24.771 14.699  1.00 31.03  ? 243 THR B CB  1 
ATOM   4875  O OG1 . THR B 1 243 ? 13.218  -24.475 13.722  1.00 27.66  ? 243 THR B OG1 1 
ATOM   4876  C CG2 . THR B 1 243 ? 13.584  -25.488 15.822  1.00 29.31  ? 243 THR B CG2 1 
ATOM   4877  N N   . VAL B 1 244 ? 14.822  -23.137 17.572  1.00 22.34  ? 244 VAL B N   1 
ATOM   4878  C CA  . VAL B 1 244 ? 15.266  -23.241 18.960  1.00 24.40  ? 244 VAL B CA  1 
ATOM   4879  C C   . VAL B 1 244 ? 14.065  -23.710 19.758  1.00 24.95  ? 244 VAL B C   1 
ATOM   4880  O O   . VAL B 1 244 ? 13.030  -23.033 19.769  1.00 22.11  ? 244 VAL B O   1 
ATOM   4881  C CB  . VAL B 1 244 ? 15.798  -21.916 19.541  1.00 25.81  ? 244 VAL B CB  1 
ATOM   4882  C CG1 . VAL B 1 244 ? 16.318  -22.130 20.959  1.00 26.02  ? 244 VAL B CG1 1 
ATOM   4883  C CG2 . VAL B 1 244 ? 16.902  -21.333 18.673  1.00 24.87  ? 244 VAL B CG2 1 
ATOM   4884  N N   . GLU B 1 245 ? 14.194  -24.867 20.416  1.00 24.04  ? 245 GLU B N   1 
ATOM   4885  C CA  . GLU B 1 245 ? 13.066  -25.552 21.028  1.00 23.41  ? 245 GLU B CA  1 
ATOM   4886  C C   . GLU B 1 245 ? 13.394  -25.909 22.469  1.00 28.18  ? 245 GLU B C   1 
ATOM   4887  O O   . GLU B 1 245 ? 14.513  -26.338 22.773  1.00 25.91  ? 245 GLU B O   1 
ATOM   4888  C CB  . GLU B 1 245 ? 12.699  -26.858 20.265  1.00 29.03  ? 245 GLU B CB  1 
ATOM   4889  C CG  . GLU B 1 245 ? 12.147  -26.704 18.825  1.00 29.43  ? 245 GLU B CG  1 
ATOM   4890  C CD  . GLU B 1 245 ? 11.688  -28.040 18.229  1.00 36.29  ? 245 GLU B CD  1 
ATOM   4891  O OE1 . GLU B 1 245 ? 12.290  -29.089 18.570  1.00 35.97  ? 245 GLU B OE1 1 
ATOM   4892  O OE2 . GLU B 1 245 ? 10.724  -28.048 17.421  1.00 38.50  ? 245 GLU B OE2 1 
ATOM   4893  N N   . THR B 1 246 ? 12.417  -25.725 23.357  1.00 24.26  ? 246 THR B N   1 
ATOM   4894  C CA  . THR B 1 246 ? 12.421  -26.451 24.613  1.00 24.57  ? 246 THR B CA  1 
ATOM   4895  C C   . THR B 1 246 ? 12.640  -27.921 24.301  1.00 25.66  ? 246 THR B C   1 
ATOM   4896  O O   . THR B 1 246 ? 12.009  -28.458 23.396  1.00 26.35  ? 246 THR B O   1 
ATOM   4897  C CB  . THR B 1 246 ? 11.076  -26.272 25.340  1.00 31.33  ? 246 THR B CB  1 
ATOM   4898  O OG1 . THR B 1 246 ? 10.790  -24.880 25.545  1.00 34.79  ? 246 THR B OG1 1 
ATOM   4899  C CG2 . THR B 1 246 ? 11.075  -26.991 26.670  1.00 26.79  ? 246 THR B CG2 1 
ATOM   4900  N N   . TYR B 1 247 ? 13.537  -28.569 25.044  1.00 29.89  ? 247 TYR B N   1 
ATOM   4901  C CA  . TYR B 1 247 ? 13.872  -29.976 24.852  1.00 25.71  ? 247 TYR B CA  1 
ATOM   4902  C C   . TYR B 1 247 ? 13.370  -30.785 26.044  1.00 32.59  ? 247 TYR B C   1 
ATOM   4903  O O   . TYR B 1 247 ? 13.682  -30.466 27.198  1.00 28.85  ? 247 TYR B O   1 
ATOM   4904  C CB  . TYR B 1 247 ? 15.383  -30.171 24.676  1.00 29.25  ? 247 TYR B CB  1 
ATOM   4905  C CG  . TYR B 1 247 ? 15.759  -31.608 24.384  1.00 33.91  ? 247 TYR B CG  1 
ATOM   4906  C CD1 . TYR B 1 247 ? 15.795  -32.088 23.087  1.00 31.82  ? 247 TYR B CD1 1 
ATOM   4907  C CD2 . TYR B 1 247 ? 16.052  -32.488 25.414  1.00 32.83  ? 247 TYR B CD2 1 
ATOM   4908  C CE1 . TYR B 1 247 ? 16.126  -33.411 22.828  1.00 37.24  ? 247 TYR B CE1 1 
ATOM   4909  C CE2 . TYR B 1 247 ? 16.380  -33.801 25.171  1.00 36.09  ? 247 TYR B CE2 1 
ATOM   4910  C CZ  . TYR B 1 247 ? 16.416  -34.265 23.879  1.00 39.02  ? 247 TYR B CZ  1 
ATOM   4911  O OH  . TYR B 1 247 ? 16.744  -35.583 23.650  1.00 38.81  ? 247 TYR B OH  1 
ATOM   4912  N N   . HIS B 1 248 ? 12.593  -31.825 25.772  1.00 31.08  ? 248 HIS B N   1 
ATOM   4913  C CA  . HIS B 1 248 ? 11.994  -32.622 26.832  1.00 36.94  ? 248 HIS B CA  1 
ATOM   4914  C C   . HIS B 1 248 ? 12.657  -33.989 26.910  1.00 37.99  ? 248 HIS B C   1 
ATOM   4915  O O   . HIS B 1 248 ? 13.003  -34.581 25.884  1.00 40.21  ? 248 HIS B O   1 
ATOM   4916  C CB  . HIS B 1 248 ? 10.489  -32.794 26.620  1.00 36.82  ? 248 HIS B CB  1 
ATOM   4917  C CG  . HIS B 1 248 ? 9.698   -31.526 26.745  1.00 35.52  ? 248 HIS B CG  1 
ATOM   4918  N ND1 . HIS B 1 248 ? 9.659   -30.570 25.756  1.00 36.63  ? 248 HIS B ND1 1 
ATOM   4919  C CD2 . HIS B 1 248 ? 8.889   -31.075 27.734  1.00 36.48  ? 248 HIS B CD2 1 
ATOM   4920  C CE1 . HIS B 1 248 ? 8.870   -29.579 26.130  1.00 32.22  ? 248 HIS B CE1 1 
ATOM   4921  N NE2 . HIS B 1 248 ? 8.394   -29.859 27.330  1.00 40.06  ? 248 HIS B NE2 1 
ATOM   4922  N N   . ARG B 1 249 ? 12.843  -34.482 28.132  1.00 38.53  ? 249 ARG B N   1 
ATOM   4923  C CA  . ARG B 1 249 ? 13.258  -35.862 28.314  1.00 33.99  ? 249 ARG B CA  1 
ATOM   4924  C C   . ARG B 1 249 ? 12.075  -36.776 28.005  1.00 42.52  ? 249 ARG B C   1 
ATOM   4925  O O   . ARG B 1 249 ? 10.972  -36.576 28.523  1.00 44.24  ? 249 ARG B O   1 
ATOM   4926  C CB  . ARG B 1 249 ? 13.758  -36.085 29.736  1.00 43.14  ? 249 ARG B CB  1 
ATOM   4927  C CG  . ARG B 1 249 ? 13.811  -37.553 30.130  1.00 52.38  ? 249 ARG B CG  1 
ATOM   4928  C CD  . ARG B 1 249 ? 14.112  -37.713 31.616  1.00 61.30  ? 249 ARG B CD  1 
ATOM   4929  N NE  . ARG B 1 249 ? 14.205  -39.101 32.068  1.00 74.86  ? 249 ARG B NE  1 
ATOM   4930  C CZ  . ARG B 1 249 ? 13.294  -40.051 31.879  1.00 73.02  ? 249 ARG B CZ  1 
ATOM   4931  N NH1 . ARG B 1 249 ? 12.139  -39.806 31.274  1.00 59.83  ? 249 ARG B NH1 1 
ATOM   4932  N NH2 . ARG B 1 249 ? 13.546  -41.282 32.320  1.00 77.28  ? 249 ARG B NH2 1 
ATOM   4933  N N   . ALA B 1 250 ? 12.297  -37.770 27.152  1.00 39.22  ? 250 ALA B N   1 
ATOM   4934  C CA  . ALA B 1 250 ? 11.221  -38.596 26.631  1.00 42.93  ? 250 ALA B CA  1 
ATOM   4935  C C   . ALA B 1 250 ? 11.275  -40.009 27.195  1.00 50.16  ? 250 ALA B C   1 
ATOM   4936  O O   . ALA B 1 250 ? 12.357  -40.587 27.357  1.00 47.05  ? 250 ALA B O   1 
ATOM   4937  C CB  . ALA B 1 250 ? 11.275  -38.657 25.102  1.00 44.08  ? 250 ALA B CB  1 
ATOM   4938  N N   . ASP B 1 251 ? 10.088  -40.552 27.489  1.00 48.02  ? 251 ASP B N   1 
ATOM   4939  C CA  . ASP B 1 251 ? 9.904   -41.982 27.722  1.00 49.55  ? 251 ASP B CA  1 
ATOM   4940  C C   . ASP B 1 251 ? 9.951   -42.763 26.405  1.00 43.49  ? 251 ASP B C   1 
ATOM   4941  O O   . ASP B 1 251 ? 10.853  -43.573 26.173  1.00 43.61  ? 251 ASP B O   1 
ATOM   4942  C CB  . ASP B 1 251 ? 8.568   -42.196 28.452  1.00 50.01  ? 251 ASP B CB  1 
ATOM   4943  C CG  . ASP B 1 251 ? 8.305   -43.656 28.812  1.00 60.40  ? 251 ASP B CG  1 
ATOM   4944  O OD1 . ASP B 1 251 ? 9.042   -44.208 29.665  1.00 60.63  ? 251 ASP B OD1 1 
ATOM   4945  O OD2 . ASP B 1 251 ? 7.346   -44.245 28.251  1.00 60.14  ? 251 ASP B OD2 1 
ATOM   4946  N N   . GLN B 1 252 ? 8.989   -42.521 25.528  1.00 45.83  ? 252 GLN B N   1 
ATOM   4947  C CA  . GLN B 1 252 ? 8.907   -43.194 24.240  1.00 43.31  ? 252 GLN B CA  1 
ATOM   4948  C C   . GLN B 1 252 ? 9.381   -42.242 23.151  1.00 37.95  ? 252 GLN B C   1 
ATOM   4949  O O   . GLN B 1 252 ? 9.018   -41.062 23.155  1.00 39.42  ? 252 GLN B O   1 
ATOM   4950  C CB  . GLN B 1 252 ? 7.470   -43.636 23.949  1.00 40.65  ? 252 GLN B CB  1 
ATOM   4951  C CG  . GLN B 1 252 ? 6.767   -44.390 25.063  1.00 41.31  ? 252 GLN B CG  1 
ATOM   4952  C CD  . GLN B 1 252 ? 5.245   -44.340 24.930  1.00 45.50  ? 252 GLN B CD  1 
ATOM   4953  O OE1 . GLN B 1 252 ? 4.692   -44.563 23.850  1.00 40.16  ? 252 GLN B OE1 1 
ATOM   4954  N NE2 . GLN B 1 252 ? 4.563   -44.042 26.035  1.00 46.35  ? 252 GLN B NE2 1 
ATOM   4955  N N   . ARG B 1 253 ? 10.197  -42.742 22.236  1.00 31.71  ? 253 ARG B N   1 
ATOM   4956  C CA  . ARG B 1 253 ? 10.454  -42.066 20.974  1.00 35.79  ? 253 ARG B CA  1 
ATOM   4957  C C   . ARG B 1 253 ? 9.815   -42.893 19.865  1.00 36.87  ? 253 ARG B C   1 
ATOM   4958  O O   . ARG B 1 253 ? 9.635   -44.108 20.007  1.00 35.11  ? 253 ARG B O   1 
ATOM   4959  C CB  . ARG B 1 253 ? 11.951  -41.895 20.703  1.00 34.38  ? 253 ARG B CB  1 
ATOM   4960  C CG  . ARG B 1 253 ? 12.687  -40.925 21.638  1.00 41.90  ? 253 ARG B CG  1 
ATOM   4961  C CD  . ARG B 1 253 ? 13.514  -39.907 20.850  1.00 42.23  ? 253 ARG B CD  1 
ATOM   4962  N NE  . ARG B 1 253 ? 13.573  -38.603 21.506  1.00 58.12  ? 253 ARG B NE  1 
ATOM   4963  C CZ  . ARG B 1 253 ? 14.689  -38.018 21.925  1.00 56.68  ? 253 ARG B CZ  1 
ATOM   4964  N NH1 . ARG B 1 253 ? 15.877  -38.564 21.714  1.00 58.51  ? 253 ARG B NH1 1 
ATOM   4965  N NH2 . ARG B 1 253 ? 14.610  -36.855 22.573  1.00 46.38  ? 253 ARG B NH2 1 
ATOM   4966  N N   . PHE B 1 254 ? 9.451   -42.238 18.767  1.00 24.88  ? 254 PHE B N   1 
ATOM   4967  C CA  . PHE B 1 254 ? 8.852   -42.978 17.670  1.00 25.31  ? 254 PHE B CA  1 
ATOM   4968  C C   . PHE B 1 254 ? 8.898   -42.124 16.422  1.00 25.07  ? 254 PHE B C   1 
ATOM   4969  O O   . PHE B 1 254 ? 9.110   -40.912 16.483  1.00 23.83  ? 254 PHE B O   1 
ATOM   4970  C CB  . PHE B 1 254 ? 7.404   -43.374 17.982  1.00 29.00  ? 254 PHE B CB  1 
ATOM   4971  C CG  . PHE B 1 254 ? 6.505   -42.193 18.193  1.00 25.10  ? 254 PHE B CG  1 
ATOM   4972  C CD1 . PHE B 1 254 ? 5.873   -41.589 17.127  1.00 24.18  ? 254 PHE B CD1 1 
ATOM   4973  C CD2 . PHE B 1 254 ? 6.340   -41.658 19.459  1.00 29.83  ? 254 PHE B CD2 1 
ATOM   4974  C CE1 . PHE B 1 254 ? 5.080   -40.477 17.325  1.00 29.34  ? 254 PHE B CE1 1 
ATOM   4975  C CE2 . PHE B 1 254 ? 5.548   -40.547 19.665  1.00 30.10  ? 254 PHE B CE2 1 
ATOM   4976  C CZ  . PHE B 1 254 ? 4.934   -39.947 18.594  1.00 28.07  ? 254 PHE B CZ  1 
ATOM   4977  N N   . PHE B 1 255 ? 8.675   -42.777 15.288  1.00 25.51  ? 255 PHE B N   1 
ATOM   4978  C CA  . PHE B 1 255 ? 8.261   -42.073 14.091  1.00 25.22  ? 255 PHE B CA  1 
ATOM   4979  C C   . PHE B 1 255 ? 7.306   -42.967 13.321  1.00 24.17  ? 255 PHE B C   1 
ATOM   4980  O O   . PHE B 1 255 ? 7.363   -44.192 13.431  1.00 22.48  ? 255 PHE B O   1 
ATOM   4981  C CB  . PHE B 1 255 ? 9.462   -41.620 13.237  1.00 24.24  ? 255 PHE B CB  1 
ATOM   4982  C CG  . PHE B 1 255 ? 10.178  -42.725 12.484  1.00 24.02  ? 255 PHE B CG  1 
ATOM   4983  C CD1 . PHE B 1 255 ? 9.753   -43.116 11.219  1.00 24.01  ? 255 PHE B CD1 1 
ATOM   4984  C CD2 . PHE B 1 255 ? 11.329  -43.308 13.006  1.00 23.86  ? 255 PHE B CD2 1 
ATOM   4985  C CE1 . PHE B 1 255 ? 10.441  -44.116 10.509  1.00 24.04  ? 255 PHE B CE1 1 
ATOM   4986  C CE2 . PHE B 1 255 ? 12.027  -44.268 12.298  1.00 21.48  ? 255 PHE B CE2 1 
ATOM   4987  C CZ  . PHE B 1 255 ? 11.577  -44.676 11.053  1.00 23.12  ? 255 PHE B CZ  1 
ATOM   4988  N N   . PHE B 1 256 ? 6.394   -42.333 12.590  1.00 21.52  ? 256 PHE B N   1 
ATOM   4989  C CA  . PHE B 1 256 ? 5.451   -43.012 11.716  1.00 23.51  ? 256 PHE B CA  1 
ATOM   4990  C C   . PHE B 1 256 ? 5.819   -42.697 10.275  1.00 24.26  ? 256 PHE B C   1 
ATOM   4991  O O   . PHE B 1 256 ? 6.087   -41.537 9.954   1.00 23.63  ? 256 PHE B O   1 
ATOM   4992  C CB  . PHE B 1 256 ? 4.015   -42.551 11.980  1.00 26.35  ? 256 PHE B CB  1 
ATOM   4993  C CG  . PHE B 1 256 ? 3.579   -42.707 13.401  1.00 24.99  ? 256 PHE B CG  1 
ATOM   4994  C CD1 . PHE B 1 256 ? 4.114   -43.712 14.197  1.00 22.04  ? 256 PHE B CD1 1 
ATOM   4995  C CD2 . PHE B 1 256 ? 2.619   -41.868 13.935  1.00 21.42  ? 256 PHE B CD2 1 
ATOM   4996  C CE1 . PHE B 1 256 ? 3.701   -43.879 15.505  1.00 27.74  ? 256 PHE B CE1 1 
ATOM   4997  C CE2 . PHE B 1 256 ? 2.210   -42.009 15.241  1.00 26.59  ? 256 PHE B CE2 1 
ATOM   4998  C CZ  . PHE B 1 256 ? 2.747   -43.026 16.036  1.00 29.94  ? 256 PHE B CZ  1 
ATOM   4999  N N   . GLU B 1 257 ? 5.824   -43.717 9.417   1.00 23.80  ? 257 GLU B N   1 
ATOM   5000  C CA  . GLU B 1 257 ? 5.971   -43.554 7.971   1.00 26.22  ? 257 GLU B CA  1 
ATOM   5001  C C   . GLU B 1 257 ? 4.648   -43.811 7.257   1.00 23.90  ? 257 GLU B C   1 
ATOM   5002  O O   . GLU B 1 257 ? 3.900   -44.717 7.633   1.00 24.47  ? 257 GLU B O   1 
ATOM   5003  C CB  . GLU B 1 257 ? 7.016   -44.517 7.387   1.00 23.77  ? 257 GLU B CB  1 
ATOM   5004  C CG  . GLU B 1 257 ? 7.597   -44.033 6.055   1.00 21.26  ? 257 GLU B CG  1 
ATOM   5005  C CD  . GLU B 1 257 ? 9.006   -44.531 5.808   1.00 25.46  ? 257 GLU B CD  1 
ATOM   5006  O OE1 . GLU B 1 257 ? 9.400   -45.489 6.521   1.00 25.85  ? 257 GLU B OE1 1 
ATOM   5007  O OE2 . GLU B 1 257 ? 9.705   -43.971 4.912   1.00 19.83  ? 257 GLU B OE2 1 
ATOM   5008  N N   . TYR B 1 258 ? 4.407   -43.059 6.180   1.00 21.78  ? 258 TYR B N   1 
ATOM   5009  C CA  . TYR B 1 258 ? 3.184   -43.153 5.393   1.00 20.10  ? 258 TYR B CA  1 
ATOM   5010  C C   . TYR B 1 258 ? 3.502   -43.126 3.905   1.00 19.38  ? 258 TYR B C   1 
ATOM   5011  O O   . TYR B 1 258 ? 4.513   -42.566 3.473   1.00 19.25  ? 258 TYR B O   1 
ATOM   5012  C CB  . TYR B 1 258 ? 2.220   -41.986 5.670   1.00 21.55  ? 258 TYR B CB  1 
ATOM   5013  C CG  . TYR B 1 258 ? 1.815   -41.814 7.099   1.00 23.03  ? 258 TYR B CG  1 
ATOM   5014  C CD1 . TYR B 1 258 ? 2.628   -41.118 7.990   1.00 22.13  ? 258 TYR B CD1 1 
ATOM   5015  C CD2 . TYR B 1 258 ? 0.602   -42.308 7.561   1.00 25.09  ? 258 TYR B CD2 1 
ATOM   5016  C CE1 . TYR B 1 258 ? 2.248   -40.948 9.304   1.00 23.63  ? 258 TYR B CE1 1 
ATOM   5017  C CE2 . TYR B 1 258 ? 0.223   -42.151 8.894   1.00 23.60  ? 258 TYR B CE2 1 
ATOM   5018  C CZ  . TYR B 1 258 ? 1.049   -41.461 9.749   1.00 20.31  ? 258 TYR B CZ  1 
ATOM   5019  O OH  . TYR B 1 258 ? 0.687   -41.281 11.059  1.00 28.69  ? 258 TYR B OH  1 
ATOM   5020  N N   . HIS B 1 259 ? 2.577   -43.668 3.115   1.00 20.78  ? 259 HIS B N   1 
ATOM   5021  C CA  . HIS B 1 259 ? 2.591   -43.499 1.671   1.00 24.37  ? 259 HIS B CA  1 
ATOM   5022  C C   . HIS B 1 259 ? 1.385   -42.676 1.240   1.00 24.05  ? 259 HIS B C   1 
ATOM   5023  O O   . HIS B 1 259 ? 0.248   -43.014 1.589   1.00 20.47  ? 259 HIS B O   1 
ATOM   5024  C CB  . HIS B 1 259 ? 2.576   -44.838 0.936   1.00 23.90  ? 259 HIS B CB  1 
ATOM   5025  C CG  . HIS B 1 259 ? 2.541   -44.681 -0.552  1.00 24.90  ? 259 HIS B CG  1 
ATOM   5026  N ND1 . HIS B 1 259 ? 1.366   -44.681 -1.272  1.00 25.46  ? 259 HIS B ND1 1 
ATOM   5027  C CD2 . HIS B 1 259 ? 3.534   -44.462 -1.450  1.00 26.51  ? 259 HIS B CD2 1 
ATOM   5028  C CE1 . HIS B 1 259 ? 1.639   -44.496 -2.554  1.00 28.05  ? 259 HIS B CE1 1 
ATOM   5029  N NE2 . HIS B 1 259 ? 2.947   -44.368 -2.690  1.00 26.97  ? 259 HIS B NE2 1 
ATOM   5030  N N   . LEU B 1 260 ? 1.641   -41.631 0.448   1.00 21.48  ? 260 LEU B N   1 
ATOM   5031  C CA  . LEU B 1 260 ? 0.654   -40.615 0.084   1.00 26.70  ? 260 LEU B CA  1 
ATOM   5032  C C   . LEU B 1 260 ? 0.434   -40.616 -1.424  1.00 24.83  ? 260 LEU B C   1 
ATOM   5033  O O   . LEU B 1 260 ? 1.377   -40.379 -2.194  1.00 20.47  ? 260 LEU B O   1 
ATOM   5034  C CB  . LEU B 1 260 ? 1.112   -39.217 0.524   1.00 20.87  ? 260 LEU B CB  1 
ATOM   5035  C CG  . LEU B 1 260 ? 0.662   -38.713 1.901   1.00 27.32  ? 260 LEU B CG  1 
ATOM   5036  C CD1 . LEU B 1 260 ? 1.079   -39.680 3.014   1.00 19.61  ? 260 LEU B CD1 1 
ATOM   5037  C CD2 . LEU B 1 260 ? 1.215   -37.332 2.147   1.00 18.01  ? 260 LEU B CD2 1 
ATOM   5038  N N   . ASP B 1 261 ? -0.805  -40.845 -1.840  1.00 23.06  ? 261 ASP B N   1 
ATOM   5039  C CA  . ASP B 1 261 ? -1.162  -40.710 -3.248  1.00 26.21  ? 261 ASP B CA  1 
ATOM   5040  C C   . ASP B 1 261 ? -2.443  -39.885 -3.351  1.00 28.17  ? 261 ASP B C   1 
ATOM   5041  O O   . ASP B 1 261 ? -2.891  -39.236 -2.390  1.00 29.58  ? 261 ASP B O   1 
ATOM   5042  C CB  . ASP B 1 261 ? -1.258  -42.086 -3.936  1.00 25.62  ? 261 ASP B CB  1 
ATOM   5043  C CG  . ASP B 1 261 ? -2.413  -42.940 -3.439  1.00 29.18  ? 261 ASP B CG  1 
ATOM   5044  O OD1 . ASP B 1 261 ? -3.388  -42.436 -2.833  1.00 30.45  ? 261 ASP B OD1 1 
ATOM   5045  O OD2 . ASP B 1 261 ? -2.348  -44.160 -3.672  1.00 33.98  ? 261 ASP B OD2 1 
ATOM   5046  N N   . GLY B 1 262 ? -3.062  -39.917 -4.535  1.00 26.62  ? 262 GLY B N   1 
ATOM   5047  C CA  . GLY B 1 262 ? -4.198  -39.060 -4.795  1.00 22.64  ? 262 GLY B CA  1 
ATOM   5048  C C   . GLY B 1 262 ? -5.438  -39.438 -4.022  1.00 34.04  ? 262 GLY B C   1 
ATOM   5049  O O   . GLY B 1 262 ? -6.338  -38.604 -3.876  1.00 32.63  ? 262 GLY B O   1 
ATOM   5050  N N   . ASP B 1 263 ? -5.495  -40.671 -3.513  1.00 29.35  ? 263 ASP B N   1 
ATOM   5051  C CA  . ASP B 1 263 ? -6.659  -41.200 -2.832  1.00 23.76  ? 263 ASP B CA  1 
ATOM   5052  C C   . ASP B 1 263 ? -6.507  -41.273 -1.319  1.00 29.69  ? 263 ASP B C   1 
ATOM   5053  O O   . ASP B 1 263 ? -7.521  -41.206 -0.624  1.00 27.26  ? 263 ASP B O   1 
ATOM   5054  C CB  . ASP B 1 263 ? -7.001  -42.612 -3.348  1.00 30.80  ? 263 ASP B CB  1 
ATOM   5055  C CG  . ASP B 1 263 ? -7.512  -42.629 -4.812  1.00 36.89  ? 263 ASP B CG  1 
ATOM   5056  O OD1 . ASP B 1 263 ? -8.079  -41.616 -5.293  1.00 34.63  ? 263 ASP B OD1 1 
ATOM   5057  O OD2 . ASP B 1 263 ? -7.404  -43.696 -5.469  1.00 37.05  ? 263 ASP B OD2 1 
ATOM   5058  N N   . ARG B 1 264 ? -5.291  -41.403 -0.781  1.00 24.70  ? 264 ARG B N   1 
ATOM   5059  C CA  . ARG B 1 264 ? -5.191  -41.708 0.642   1.00 26.81  ? 264 ARG B CA  1 
ATOM   5060  C C   . ARG B 1 264 ? -3.766  -41.531 1.170   1.00 28.10  ? 264 ARG B C   1 
ATOM   5061  O O   . ARG B 1 264 ? -2.792  -41.480 0.419   1.00 26.32  ? 264 ARG B O   1 
ATOM   5062  C CB  . ARG B 1 264 ? -5.666  -43.141 0.925   1.00 29.00  ? 264 ARG B CB  1 
ATOM   5063  C CG  . ARG B 1 264 ? -4.558  -44.211 0.822   1.00 28.88  ? 264 ARG B CG  1 
ATOM   5064  C CD  . ARG B 1 264 ? -4.417  -44.754 -0.604  1.00 28.41  ? 264 ARG B CD  1 
ATOM   5065  N NE  . ARG B 1 264 ? -3.394  -45.789 -0.751  1.00 31.00  ? 264 ARG B NE  1 
ATOM   5066  C CZ  . ARG B 1 264 ? -2.083  -45.574 -0.725  1.00 31.16  ? 264 ARG B CZ  1 
ATOM   5067  N NH1 . ARG B 1 264 ? -1.579  -44.361 -0.535  1.00 25.24  ? 264 ARG B NH1 1 
ATOM   5068  N NH2 . ARG B 1 264 ? -1.254  -46.600 -0.896  1.00 28.08  ? 264 ARG B NH2 1 
ATOM   5069  N N   . ALA B 1 265 ? -3.667  -41.463 2.487   1.00 27.03  ? 265 ALA B N   1 
ATOM   5070  C CA  . ALA B 1 265 ? -2.407  -41.601 3.198   1.00 29.27  ? 265 ALA B CA  1 
ATOM   5071  C C   . ALA B 1 265 ? -2.446  -42.941 3.929   1.00 26.59  ? 265 ALA B C   1 
ATOM   5072  O O   . ALA B 1 265 ? -3.239  -43.124 4.856   1.00 26.26  ? 265 ALA B O   1 
ATOM   5073  C CB  . ALA B 1 265 ? -2.199  -40.441 4.167   1.00 25.17  ? 265 ALA B CB  1 
ATOM   5074  N N   . ARG B 1 266 ? -1.606  -43.882 3.520   1.00 24.56  ? 266 ARG B N   1 
ATOM   5075  C CA  . ARG B 1 266 ? -1.610  -45.210 4.130   1.00 23.91  ? 266 ARG B CA  1 
ATOM   5076  C C   . ARG B 1 266 ? -0.486  -45.291 5.166   1.00 25.02  ? 266 ARG B C   1 
ATOM   5077  O O   . ARG B 1 266 ? 0.690   -45.074 4.847   1.00 21.00  ? 266 ARG B O   1 
ATOM   5078  C CB  . ARG B 1 266 ? -1.499  -46.293 3.054   1.00 26.49  ? 266 ARG B CB  1 
ATOM   5079  C CG  . ARG B 1 266 ? -1.180  -47.728 3.543   1.00 35.87  ? 266 ARG B CG  1 
ATOM   5080  C CD  . ARG B 1 266 ? -2.424  -48.553 3.862   1.00 39.91  ? 266 ARG B CD  1 
ATOM   5081  N NE  . ARG B 1 266 ? -2.162  -49.639 4.809   1.00 50.00  ? 266 ARG B NE  1 
ATOM   5082  C CZ  . ARG B 1 266 ? -2.093  -49.500 6.130   1.00 40.32  ? 266 ARG B CZ  1 
ATOM   5083  N NH1 . ARG B 1 266 ? -2.199  -48.319 6.709   1.00 33.02  ? 266 ARG B NH1 1 
ATOM   5084  N NH2 . ARG B 1 266 ? -1.900  -50.577 6.889   1.00 47.97  ? 266 ARG B NH2 1 
ATOM   5085  N N   . PHE B 1 267 ? -0.864  -45.525 6.418   1.00 22.80  ? 267 PHE B N   1 
ATOM   5086  C CA  . PHE B 1 267 ? 0.098   -45.795 7.474   1.00 26.06  ? 267 PHE B CA  1 
ATOM   5087  C C   . PHE B 1 267 ? 0.899   -47.051 7.140   1.00 25.83  ? 267 PHE B C   1 
ATOM   5088  O O   . PHE B 1 267 ? 0.325   -48.086 6.816   1.00 23.55  ? 267 PHE B O   1 
ATOM   5089  C CB  . PHE B 1 267 ? -0.650  -45.969 8.799   1.00 26.10  ? 267 PHE B CB  1 
ATOM   5090  C CG  . PHE B 1 267 ? 0.238   -46.293 9.958   1.00 29.61  ? 267 PHE B CG  1 
ATOM   5091  C CD1 . PHE B 1 267 ? 0.638   -47.598 10.215  1.00 30.36  ? 267 PHE B CD1 1 
ATOM   5092  C CD2 . PHE B 1 267 ? 0.686   -45.289 10.790  1.00 27.15  ? 267 PHE B CD2 1 
ATOM   5093  C CE1 . PHE B 1 267 ? 1.470   -47.886 11.286  1.00 27.17  ? 267 PHE B CE1 1 
ATOM   5094  C CE2 . PHE B 1 267 ? 1.521   -45.576 11.852  1.00 26.58  ? 267 PHE B CE2 1 
ATOM   5095  C CZ  . PHE B 1 267 ? 1.917   -46.866 12.097  1.00 23.48  ? 267 PHE B CZ  1 
ATOM   5096  N N   . LEU B 1 268 ? 2.227   -46.961 7.216   1.00 21.00  ? 268 LEU B N   1 
ATOM   5097  C CA  . LEU B 1 268 ? 3.093   -48.077 6.840   1.00 25.68  ? 268 LEU B CA  1 
ATOM   5098  C C   . LEU B 1 268 ? 3.617   -48.840 8.048   1.00 24.25  ? 268 LEU B C   1 
ATOM   5099  O O   . LEU B 1 268 ? 3.464   -50.062 8.127   1.00 26.53  ? 268 LEU B O   1 
ATOM   5100  C CB  . LEU B 1 268 ? 4.268   -47.571 5.994   1.00 23.59  ? 268 LEU B CB  1 
ATOM   5101  C CG  . LEU B 1 268 ? 3.812   -46.954 4.672   1.00 22.67  ? 268 LEU B CG  1 
ATOM   5102  C CD1 . LEU B 1 268 ? 5.032   -46.439 3.933   1.00 22.28  ? 268 LEU B CD1 1 
ATOM   5103  C CD2 . LEU B 1 268 ? 3.066   -48.015 3.859   1.00 21.31  ? 268 LEU B CD2 1 
ATOM   5104  N N   . HIS B 1 269 ? 4.223   -48.134 8.995   1.00 22.94  ? 269 HIS B N   1 
ATOM   5105  C CA  . HIS B 1 269 ? 4.771   -48.727 10.199  1.00 25.90  ? 269 HIS B CA  1 
ATOM   5106  C C   . HIS B 1 269 ? 5.091   -47.609 11.171  1.00 29.69  ? 269 HIS B C   1 
ATOM   5107  O O   . HIS B 1 269 ? 5.192   -46.439 10.789  1.00 26.38  ? 269 HIS B O   1 
ATOM   5108  C CB  . HIS B 1 269 ? 6.043   -49.527 9.903   1.00 26.13  ? 269 HIS B CB  1 
ATOM   5109  C CG  . HIS B 1 269 ? 7.153   -48.684 9.368   1.00 23.61  ? 269 HIS B CG  1 
ATOM   5110  N ND1 . HIS B 1 269 ? 8.181   -48.221 10.158  1.00 23.36  ? 269 HIS B ND1 1 
ATOM   5111  C CD2 . HIS B 1 269 ? 7.384   -48.201 8.122   1.00 25.40  ? 269 HIS B CD2 1 
ATOM   5112  C CE1 . HIS B 1 269 ? 9.005   -47.497 9.417   1.00 27.56  ? 269 HIS B CE1 1 
ATOM   5113  N NE2 . HIS B 1 269 ? 8.535   -47.455 8.181   1.00 26.77  ? 269 HIS B NE2 1 
ATOM   5114  N N   . SER B 1 270 ? 5.274   -47.995 12.428  1.00 26.35  ? 270 SER B N   1 
ATOM   5115  C CA  . SER B 1 270 ? 5.968   -47.188 13.417  1.00 27.18  ? 270 SER B CA  1 
ATOM   5116  C C   . SER B 1 270 ? 7.329   -47.819 13.713  1.00 29.30  ? 270 SER B C   1 
ATOM   5117  O O   . SER B 1 270 ? 7.520   -49.035 13.561  1.00 29.05  ? 270 SER B O   1 
ATOM   5118  C CB  . SER B 1 270 ? 5.140   -47.089 14.706  1.00 29.67  ? 270 SER B CB  1 
ATOM   5119  O OG  . SER B 1 270 ? 5.083   -48.363 15.349  1.00 29.65  ? 270 SER B OG  1 
ATOM   5120  N N   . SER B 1 271 ? 8.275   -46.993 14.161  1.00 25.52  ? 271 SER B N   1 
ATOM   5121  C CA  . SER B 1 271 ? 9.591   -47.506 14.531  1.00 29.78  ? 271 SER B CA  1 
ATOM   5122  C C   . SER B 1 271 ? 10.218  -46.631 15.605  1.00 29.62  ? 271 SER B C   1 
ATOM   5123  O O   . SER B 1 271 ? 9.776   -45.508 15.859  1.00 28.53  ? 271 SER B O   1 
ATOM   5124  C CB  . SER B 1 271 ? 10.509  -47.600 13.309  1.00 31.60  ? 271 SER B CB  1 
ATOM   5125  O OG  . SER B 1 271 ? 10.065  -48.641 12.449  1.00 31.39  ? 271 SER B OG  1 
ATOM   5126  N N   . ILE B 1 272 ? 11.257  -47.163 16.244  1.00 35.31  ? 272 ILE B N   1 
ATOM   5127  C CA  . ILE B 1 272 ? 11.941  -46.496 17.348  1.00 32.44  ? 272 ILE B CA  1 
ATOM   5128  C C   . ILE B 1 272 ? 13.395  -46.296 16.956  1.00 32.57  ? 272 ILE B C   1 
ATOM   5129  O O   . ILE B 1 272 ? 14.093  -47.266 16.657  1.00 31.99  ? 272 ILE B O   1 
ATOM   5130  C CB  . ILE B 1 272 ? 11.861  -47.312 18.651  1.00 34.10  ? 272 ILE B CB  1 
ATOM   5131  C CG1 . ILE B 1 272 ? 10.422  -47.543 19.102  1.00 32.23  ? 272 ILE B CG1 1 
ATOM   5132  C CG2 . ILE B 1 272 ? 12.650  -46.630 19.777  1.00 35.71  ? 272 ILE B CG2 1 
ATOM   5133  C CD1 . ILE B 1 272 ? 10.353  -48.476 20.350  1.00 34.86  ? 272 ILE B CD1 1 
ATOM   5134  N N   . LEU B 1 273 ? 13.866  -45.056 16.993  1.00 33.33  ? 273 LEU B N   1 
ATOM   5135  C CA  . LEU B 1 273 ? 15.294  -44.819 16.815  1.00 39.20  ? 273 LEU B CA  1 
ATOM   5136  C C   . LEU B 1 273 ? 16.017  -45.107 18.123  1.00 40.12  ? 273 LEU B C   1 
ATOM   5137  O O   . LEU B 1 273 ? 15.549  -44.731 19.203  1.00 35.39  ? 273 LEU B O   1 
ATOM   5138  C CB  . LEU B 1 273 ? 15.570  -43.391 16.362  1.00 42.83  ? 273 LEU B CB  1 
ATOM   5139  C CG  . LEU B 1 273 ? 14.627  -42.879 15.286  1.00 35.07  ? 273 LEU B CG  1 
ATOM   5140  C CD1 . LEU B 1 273 ? 13.565  -41.998 15.926  1.00 41.51  ? 273 LEU B CD1 1 
ATOM   5141  C CD2 . LEU B 1 273 ? 15.419  -42.138 14.249  1.00 37.93  ? 273 LEU B CD2 1 
ATOM   5142  N N   . LYS B 1 274 ? 17.148  -45.805 18.012  1.00 42.63  ? 274 LYS B N   1 
ATOM   5143  C CA  . LYS B 1 274 ? 17.858  -46.379 19.144  1.00 43.92  ? 274 LYS B CA  1 
ATOM   5144  C C   . LYS B 1 274 ? 19.232  -45.737 19.295  1.00 50.29  ? 274 LYS B C   1 
ATOM   5145  O O   . LYS B 1 274 ? 19.934  -45.488 18.302  1.00 50.87  ? 274 LYS B O   1 
ATOM   5146  C CB  . LYS B 1 274 ? 18.000  -47.899 18.987  1.00 39.78  ? 274 LYS B CB  1 
ATOM   5147  C CG  . LYS B 1 274 ? 16.666  -48.642 18.854  1.00 40.21  ? 274 LYS B CG  1 
ATOM   5148  C CD  . LYS B 1 274 ? 15.807  -48.545 20.109  1.00 35.25  ? 274 LYS B CD  1 
ATOM   5149  C CE  . LYS B 1 274 ? 16.527  -49.001 21.388  1.00 43.32  ? 274 LYS B CE  1 
ATOM   5150  N NZ  . LYS B 1 274 ? 17.582  -50.046 21.174  1.00 47.18  ? 274 LYS B NZ  1 
ATOM   5151  N N   . TYR B 1 275 ? 19.601  -45.472 20.549  1.00 50.16  ? 275 TYR B N   1 
ATOM   5152  C CA  . TYR B 1 275 ? 20.863  -44.839 20.905  1.00 52.81  ? 275 TYR B CA  1 
ATOM   5153  C C   . TYR B 1 275 ? 21.416  -45.539 22.139  1.00 55.95  ? 275 TYR B C   1 
ATOM   5154  O O   . TYR B 1 275 ? 20.799  -46.465 22.673  1.00 51.11  ? 275 TYR B O   1 
ATOM   5155  C CB  . TYR B 1 275 ? 20.682  -43.346 21.195  1.00 52.12  ? 275 TYR B CB  1 
ATOM   5156  C CG  . TYR B 1 275 ? 19.724  -42.592 20.296  1.00 47.30  ? 275 TYR B CG  1 
ATOM   5157  C CD1 . TYR B 1 275 ? 18.353  -42.590 20.542  1.00 47.67  ? 275 TYR B CD1 1 
ATOM   5158  C CD2 . TYR B 1 275 ? 20.197  -41.841 19.230  1.00 45.40  ? 275 TYR B CD2 1 
ATOM   5159  C CE1 . TYR B 1 275 ? 17.488  -41.873 19.731  1.00 44.37  ? 275 TYR B CE1 1 
ATOM   5160  C CE2 . TYR B 1 275 ? 19.349  -41.136 18.423  1.00 39.04  ? 275 TYR B CE2 1 
ATOM   5161  C CZ  . TYR B 1 275 ? 18.002  -41.150 18.670  1.00 41.26  ? 275 TYR B CZ  1 
ATOM   5162  O OH  . TYR B 1 275 ? 17.175  -40.432 17.842  1.00 42.76  ? 275 TYR B OH  1 
ATOM   5163  N N   . GLU B 1 276 ? 22.583  -45.086 22.610  1.00 62.59  ? 276 GLU B N   1 
ATOM   5164  C CA  . GLU B 1 276 ? 23.080  -45.485 23.937  1.00 62.58  ? 276 GLU B CA  1 
ATOM   5165  C C   . GLU B 1 276 ? 23.633  -44.294 24.712  1.00 65.70  ? 276 GLU B C   1 
ATOM   5166  O O   . GLU B 1 276 ? 22.893  -43.384 25.092  1.00 66.40  ? 276 GLU B O   1 
ATOM   5167  C CB  . GLU B 1 276 ? 24.156  -46.568 23.832  1.00 62.84  ? 276 GLU B CB  1 
ATOM   5168  C CG  . GLU B 1 276 ? 24.683  -47.035 25.189  1.00 68.26  ? 276 GLU B CG  1 
ATOM   5169  C CD  . GLU B 1 276 ? 25.338  -48.411 25.122  1.00 77.70  ? 276 GLU B CD  1 
ATOM   5170  O OE1 . GLU B 1 276 ? 25.702  -48.840 24.005  1.00 68.90  ? 276 GLU B OE1 1 
ATOM   5171  O OE2 . GLU B 1 276 ? 25.501  -49.059 26.183  1.00 77.19  ? 276 GLU B OE2 1 
ATOM   5172  N N   . SER B 1 285 ? 27.275  -36.708 21.765  1.00 59.28  ? 285 SER B N   1 
ATOM   5173  C CA  . SER B 1 285 ? 26.088  -37.123 22.501  1.00 49.96  ? 285 SER B CA  1 
ATOM   5174  C C   . SER B 1 285 ? 25.725  -38.527 22.083  1.00 55.90  ? 285 SER B C   1 
ATOM   5175  O O   . SER B 1 285 ? 26.453  -39.133 21.300  1.00 62.64  ? 285 SER B O   1 
ATOM   5176  C CB  . SER B 1 285 ? 24.948  -36.164 22.235  1.00 48.87  ? 285 SER B CB  1 
ATOM   5177  O OG  . SER B 1 285 ? 25.467  -34.949 21.719  1.00 47.67  ? 285 SER B OG  1 
ATOM   5178  N N   . ALA B 1 286 ? 24.605  -39.043 22.584  1.00 54.42  ? 286 ALA B N   1 
ATOM   5179  C CA  . ALA B 1 286 ? 24.223  -40.423 22.297  1.00 58.68  ? 286 ALA B CA  1 
ATOM   5180  C C   . ALA B 1 286 ? 24.113  -40.656 20.795  1.00 50.58  ? 286 ALA B C   1 
ATOM   5181  O O   . ALA B 1 286 ? 23.355  -39.970 20.103  1.00 55.06  ? 286 ALA B O   1 
ATOM   5182  C CB  . ALA B 1 286 ? 22.902  -40.756 22.985  1.00 60.35  ? 286 ALA B CB  1 
ATOM   5183  N N   . LYS B 1 287 ? 24.880  -41.618 20.294  1.00 47.38  ? 287 LYS B N   1 
ATOM   5184  C CA  . LYS B 1 287 ? 24.904  -41.916 18.871  1.00 50.45  ? 287 LYS B CA  1 
ATOM   5185  C C   . LYS B 1 287 ? 23.717  -42.802 18.483  1.00 55.30  ? 287 LYS B C   1 
ATOM   5186  O O   . LYS B 1 287 ? 23.281  -43.661 19.257  1.00 51.08  ? 287 LYS B O   1 
ATOM   5187  C CB  . LYS B 1 287 ? 26.233  -42.588 18.513  1.00 54.79  ? 287 LYS B CB  1 
ATOM   5188  C CG  . LYS B 1 287 ? 26.318  -43.183 17.117  1.00 55.48  ? 287 LYS B CG  1 
ATOM   5189  C CD  . LYS B 1 287 ? 27.665  -43.853 16.875  1.00 58.48  ? 287 LYS B CD  1 
ATOM   5190  C CE  . LYS B 1 287 ? 27.712  -45.259 17.450  1.00 56.88  ? 287 LYS B CE  1 
ATOM   5191  N NZ  . LYS B 1 287 ? 28.050  -46.297 16.433  1.00 51.09  ? 287 LYS B NZ  1 
ATOM   5192  N N   . TRP B 1 288 ? 23.178  -42.566 17.284  1.00 54.02  ? 288 TRP B N   1 
ATOM   5193  C CA  . TRP B 1 288 ? 22.127  -43.407 16.708  1.00 48.23  ? 288 TRP B CA  1 
ATOM   5194  C C   . TRP B 1 288 ? 22.705  -44.779 16.387  1.00 46.64  ? 288 TRP B C   1 
ATOM   5195  O O   . TRP B 1 288 ? 23.556  -44.907 15.502  1.00 44.85  ? 288 TRP B O   1 
ATOM   5196  C CB  . TRP B 1 288 ? 21.571  -42.742 15.453  1.00 41.64  ? 288 TRP B CB  1 
ATOM   5197  C CG  . TRP B 1 288 ? 20.598  -43.574 14.640  1.00 42.65  ? 288 TRP B CG  1 
ATOM   5198  C CD1 . TRP B 1 288 ? 19.466  -44.183 15.090  1.00 40.95  ? 288 TRP B CD1 1 
ATOM   5199  C CD2 . TRP B 1 288 ? 20.666  -43.847 13.230  1.00 37.41  ? 288 TRP B CD2 1 
ATOM   5200  N NE1 . TRP B 1 288 ? 18.828  -44.822 14.052  1.00 41.17  ? 288 TRP B NE1 1 
ATOM   5201  C CE2 . TRP B 1 288 ? 19.544  -44.631 12.901  1.00 34.91  ? 288 TRP B CE2 1 
ATOM   5202  C CE3 . TRP B 1 288 ? 21.566  -43.500 12.215  1.00 39.55  ? 288 TRP B CE3 1 
ATOM   5203  C CZ2 . TRP B 1 288 ? 19.302  -45.086 11.606  1.00 36.33  ? 288 TRP B CZ2 1 
ATOM   5204  C CZ3 . TRP B 1 288 ? 21.325  -43.953 10.928  1.00 39.68  ? 288 TRP B CZ3 1 
ATOM   5205  C CH2 . TRP B 1 288 ? 20.204  -44.741 10.637  1.00 34.74  ? 288 TRP B CH2 1 
ATOM   5206  N N   . ILE B 1 289 ? 22.258  -45.816 17.093  1.00 47.66  ? 289 ILE B N   1 
ATOM   5207  C CA  . ILE B 1 289 ? 22.821  -47.142 16.854  1.00 50.70  ? 289 ILE B CA  1 
ATOM   5208  C C   . ILE B 1 289 ? 21.936  -48.014 15.964  1.00 50.76  ? 289 ILE B C   1 
ATOM   5209  O O   . ILE B 1 289 ? 22.442  -48.975 15.362  1.00 49.04  ? 289 ILE B O   1 
ATOM   5210  C CB  . ILE B 1 289 ? 23.141  -47.877 18.172  1.00 49.69  ? 289 ILE B CB  1 
ATOM   5211  C CG1 . ILE B 1 289 ? 22.003  -47.755 19.183  1.00 53.27  ? 289 ILE B CG1 1 
ATOM   5212  C CG2 . ILE B 1 289 ? 24.430  -47.330 18.776  1.00 57.67  ? 289 ILE B CG2 1 
ATOM   5213  C CD1 . ILE B 1 289 ? 22.377  -48.277 20.567  1.00 52.25  ? 289 ILE B CD1 1 
ATOM   5214  N N   . GLY B 1 290 ? 20.652  -47.694 15.832  1.00 42.75  ? 290 GLY B N   1 
ATOM   5215  C CA  . GLY B 1 290 ? 19.814  -48.442 14.910  1.00 44.16  ? 290 GLY B CA  1 
ATOM   5216  C C   . GLY B 1 290 ? 18.364  -48.089 15.103  1.00 39.78  ? 290 GLY B C   1 
ATOM   5217  O O   . GLY B 1 290 ? 18.029  -46.957 15.463  1.00 43.23  ? 290 GLY B O   1 
ATOM   5218  N N   . LEU B 1 291 ? 17.501  -49.071 14.856  1.00 38.68  ? 291 LEU B N   1 
ATOM   5219  C CA  . LEU B 1 291 ? 16.101  -48.857 15.164  1.00 36.06  ? 291 LEU B CA  1 
ATOM   5220  C C   . LEU B 1 291 ? 15.378  -50.189 15.283  1.00 36.84  ? 291 LEU B C   1 
ATOM   5221  O O   . LEU B 1 291 ? 15.731  -51.170 14.624  1.00 36.57  ? 291 LEU B O   1 
ATOM   5222  C CB  . LEU B 1 291 ? 15.433  -47.939 14.128  1.00 39.34  ? 291 LEU B CB  1 
ATOM   5223  C CG  . LEU B 1 291 ? 15.201  -48.302 12.683  1.00 34.33  ? 291 LEU B CG  1 
ATOM   5224  C CD1 . LEU B 1 291 ? 13.869  -48.989 12.589  1.00 34.83  ? 291 LEU B CD1 1 
ATOM   5225  C CD2 . LEU B 1 291 ? 15.225  -47.030 11.851  1.00 32.59  ? 291 LEU B CD2 1 
ATOM   5226  N N   . ASP B 1 292 ? 14.374  -50.200 16.158  1.00 33.16  ? 292 ASP B N   1 
ATOM   5227  C CA  . ASP B 1 292 ? 13.548  -51.353 16.467  1.00 31.71  ? 292 ASP B CA  1 
ATOM   5228  C C   . ASP B 1 292 ? 12.135  -51.113 15.960  1.00 34.02  ? 292 ASP B C   1 
ATOM   5229  O O   . ASP B 1 292 ? 11.690  -49.966 15.842  1.00 31.35  ? 292 ASP B O   1 
ATOM   5230  C CB  . ASP B 1 292 ? 13.513  -51.607 17.976  1.00 32.98  ? 292 ASP B CB  1 
ATOM   5231  C CG  . ASP B 1 292 ? 14.900  -51.712 18.591  1.00 34.97  ? 292 ASP B CG  1 
ATOM   5232  O OD1 . ASP B 1 292 ? 15.897  -51.898 17.844  1.00 30.98  ? 292 ASP B OD1 1 
ATOM   5233  O OD2 . ASP B 1 292 ? 14.985  -51.595 19.831  1.00 35.72  ? 292 ASP B OD2 1 
ATOM   5234  N N   . SER B 1 293 ? 11.419  -52.195 15.679  1.00 30.31  ? 293 SER B N   1 
ATOM   5235  C CA  . SER B 1 293 ? 10.107  -51.983 15.086  1.00 35.20  ? 293 SER B CA  1 
ATOM   5236  C C   . SER B 1 293 ? 9.044   -52.792 15.812  1.00 40.64  ? 293 SER B C   1 
ATOM   5237  O O   . SER B 1 293 ? 9.380   -53.642 16.642  1.00 44.15  ? 293 SER B O   1 
ATOM   5238  C CB  . SER B 1 293 ? 10.109  -52.310 13.599  1.00 35.80  ? 293 SER B CB  1 
ATOM   5239  O OG  . SER B 1 293 ? 9.195   -51.480 12.881  1.00 33.31  ? 293 SER B OG  1 
ATOM   5240  N N   . PRO B 1 294 ? 7.788   -52.700 15.388  1.00 36.64  ? 294 PRO B N   1 
ATOM   5241  C CA  . PRO B 1 294 ? 6.764   -52.127 16.253  1.00 36.48  ? 294 PRO B CA  1 
ATOM   5242  C C   . PRO B 1 294 ? 7.352   -51.147 17.263  1.00 38.55  ? 294 PRO B C   1 
ATOM   5243  O O   . PRO B 1 294 ? 8.079   -51.543 18.178  1.00 30.33  ? 294 PRO B O   1 
ATOM   5244  C CB  . PRO B 1 294 ? 6.158   -53.365 16.915  1.00 40.43  ? 294 PRO B CB  1 
ATOM   5245  C CG  . PRO B 1 294 ? 6.180   -54.371 15.802  1.00 41.29  ? 294 PRO B CG  1 
ATOM   5246  C CD  . PRO B 1 294 ? 7.312   -53.988 14.850  1.00 40.66  ? 294 PRO B CD  1 
ATOM   5247  N N   . SER B 1 295 ? 7.060   -49.855 17.102  1.00 36.07  ? 295 SER B N   1 
ATOM   5248  C CA  . SER B 1 295 ? 7.267   -48.938 18.211  1.00 34.74  ? 295 SER B CA  1 
ATOM   5249  C C   . SER B 1 295 ? 6.315   -49.298 19.350  1.00 32.79  ? 295 SER B C   1 
ATOM   5250  O O   . SER B 1 295 ? 5.447   -50.164 19.225  1.00 35.34  ? 295 SER B O   1 
ATOM   5251  C CB  . SER B 1 295 ? 7.028   -47.492 17.784  1.00 32.05  ? 295 SER B CB  1 
ATOM   5252  O OG  . SER B 1 295 ? 5.645   -47.181 17.851  1.00 26.57  ? 295 SER B OG  1 
ATOM   5253  N N   . ARG B 1 296 ? 6.471   -48.606 20.471  1.00 35.77  ? 296 ARG B N   1 
ATOM   5254  C CA  . ARG B 1 296 ? 5.591   -48.802 21.611  1.00 37.84  ? 296 ARG B CA  1 
ATOM   5255  C C   . ARG B 1 296 ? 4.599   -47.664 21.765  1.00 39.62  ? 296 ARG B C   1 
ATOM   5256  O O   . ARG B 1 296 ? 4.045   -47.473 22.853  1.00 44.26  ? 296 ARG B O   1 
ATOM   5257  C CB  . ARG B 1 296 ? 6.413   -48.965 22.890  1.00 36.54  ? 296 ARG B CB  1 
ATOM   5258  C CG  . ARG B 1 296 ? 6.604   -50.397 23.315  1.00 39.59  ? 296 ARG B CG  1 
ATOM   5259  C CD  . ARG B 1 296 ? 7.968   -50.897 22.889  1.00 53.66  ? 296 ARG B CD  1 
ATOM   5260  N NE  . ARG B 1 296 ? 9.039   -50.115 23.498  1.00 60.83  ? 296 ARG B NE  1 
ATOM   5261  C CZ  . ARG B 1 296 ? 10.322  -50.455 23.489  1.00 60.46  ? 296 ARG B CZ  1 
ATOM   5262  N NH1 . ARG B 1 296 ? 10.739  -51.568 22.900  1.00 59.18  ? 296 ARG B NH1 1 
ATOM   5263  N NH2 . ARG B 1 296 ? 11.206  -49.663 24.092  1.00 54.49  ? 296 ARG B NH2 1 
ATOM   5264  N N   . SER B 1 297 ? 4.363   -46.908 20.700  1.00 35.34  ? 297 SER B N   1 
ATOM   5265  C CA  . SER B 1 297 ? 3.680   -45.629 20.795  1.00 35.68  ? 297 SER B CA  1 
ATOM   5266  C C   . SER B 1 297 ? 2.513   -45.545 19.817  1.00 35.29  ? 297 SER B C   1 
ATOM   5267  O O   . SER B 1 297 ? 2.176   -44.460 19.345  1.00 36.23  ? 297 SER B O   1 
ATOM   5268  C CB  . SER B 1 297 ? 4.660   -44.486 20.545  1.00 39.04  ? 297 SER B CB  1 
ATOM   5269  O OG  . SER B 1 297 ? 5.828   -44.624 21.341  1.00 41.17  ? 297 SER B OG  1 
ATOM   5270  N N   . GLU B 1 298 ? 1.883   -46.675 19.507  1.00 32.81  ? 298 GLU B N   1 
ATOM   5271  C CA  . GLU B 1 298 ? 0.769   -46.720 18.560  1.00 35.71  ? 298 GLU B CA  1 
ATOM   5272  C C   . GLU B 1 298 ? -0.548  -46.771 19.331  1.00 38.21  ? 298 GLU B C   1 
ATOM   5273  O O   . GLU B 1 298 ? -1.142  -47.827 19.539  1.00 37.72  ? 298 GLU B O   1 
ATOM   5274  C CB  . GLU B 1 298 ? 0.914   -47.914 17.630  1.00 31.86  ? 298 GLU B CB  1 
ATOM   5275  C CG  . GLU B 1 298 ? 1.930   -47.720 16.524  1.00 34.06  ? 298 GLU B CG  1 
ATOM   5276  C CD  . GLU B 1 298 ? 1.888   -48.853 15.516  1.00 37.23  ? 298 GLU B CD  1 
ATOM   5277  O OE1 . GLU B 1 298 ? 0.774   -49.355 15.241  1.00 40.88  ? 298 GLU B OE1 1 
ATOM   5278  O OE2 . GLU B 1 298 ? 2.959   -49.242 15.000  1.00 33.69  ? 298 GLU B OE2 1 
ATOM   5279  N N   . PHE B 1 299 ? -1.014  -45.600 19.749  1.00 32.86  ? 299 PHE B N   1 
ATOM   5280  C CA  . PHE B 1 299 ? -2.316  -45.483 20.382  1.00 37.35  ? 299 PHE B CA  1 
ATOM   5281  C C   . PHE B 1 299 ? -2.974  -44.202 19.891  1.00 36.74  ? 299 PHE B C   1 
ATOM   5282  O O   . PHE B 1 299 ? -2.349  -43.391 19.206  1.00 32.58  ? 299 PHE B O   1 
ATOM   5283  C CB  . PHE B 1 299 ? -2.200  -45.493 21.908  1.00 37.57  ? 299 PHE B CB  1 
ATOM   5284  C CG  . PHE B 1 299 ? -1.098  -44.618 22.430  1.00 41.23  ? 299 PHE B CG  1 
ATOM   5285  C CD1 . PHE B 1 299 ? 0.179   -45.119 22.607  1.00 42.58  ? 299 PHE B CD1 1 
ATOM   5286  C CD2 . PHE B 1 299 ? -1.336  -43.292 22.741  1.00 44.75  ? 299 PHE B CD2 1 
ATOM   5287  C CE1 . PHE B 1 299 ? 1.200   -44.314 23.088  1.00 40.34  ? 299 PHE B CE1 1 
ATOM   5288  C CE2 . PHE B 1 299 ? -0.316  -42.482 23.232  1.00 41.80  ? 299 PHE B CE2 1 
ATOM   5289  C CZ  . PHE B 1 299 ? 0.952   -42.998 23.396  1.00 40.33  ? 299 PHE B CZ  1 
ATOM   5290  N N   . GLU B 1 300 ? -4.238  -44.009 20.298  1.00 39.54  ? 300 GLU B N   1 
ATOM   5291  C CA  . GLU B 1 300 ? -5.066  -42.928 19.760  1.00 37.53  ? 300 GLU B CA  1 
ATOM   5292  C C   . GLU B 1 300 ? -4.411  -41.555 19.925  1.00 36.35  ? 300 GLU B C   1 
ATOM   5293  O O   . GLU B 1 300 ? -4.498  -40.713 19.022  1.00 34.13  ? 300 GLU B O   1 
ATOM   5294  C CB  . GLU B 1 300 ? -6.455  -42.955 20.417  1.00 41.10  ? 300 GLU B CB  1 
ATOM   5295  C CG  . GLU B 1 300 ? -6.526  -42.342 21.824  1.00 47.57  ? 300 GLU B CG  1 
ATOM   5296  C CD  . GLU B 1 300 ? -7.956  -42.187 22.360  1.00 61.37  ? 300 GLU B CD  1 
ATOM   5297  O OE1 . GLU B 1 300 ? -8.920  -42.566 21.648  1.00 61.83  ? 300 GLU B OE1 1 
ATOM   5298  O OE2 . GLU B 1 300 ? -8.109  -41.675 23.495  1.00 53.93  ? 300 GLU B OE2 1 
ATOM   5299  N N   . ALA B 1 301 ? -3.727  -41.313 21.050  1.00 32.06  ? 301 ALA B N   1 
ATOM   5300  C CA  . ALA B 1 301 ? -3.197  -39.973 21.299  1.00 35.48  ? 301 ALA B CA  1 
ATOM   5301  C C   . ALA B 1 301 ? -2.014  -39.634 20.411  1.00 35.77  ? 301 ALA B C   1 
ATOM   5302  O O   . ALA B 1 301 ? -1.586  -38.473 20.389  1.00 31.78  ? 301 ALA B O   1 
ATOM   5303  C CB  . ALA B 1 301 ? -2.784  -39.812 22.760  1.00 35.53  ? 301 ALA B CB  1 
ATOM   5304  N N   . THR B 1 302 ? -1.478  -40.618 19.697  1.00 31.17  ? 302 THR B N   1 
ATOM   5305  C CA  . THR B 1 302 ? -0.381  -40.440 18.760  1.00 34.15  ? 302 THR B CA  1 
ATOM   5306  C C   . THR B 1 302 ? -0.824  -40.500 17.309  1.00 30.20  ? 302 THR B C   1 
ATOM   5307  O O   . THR B 1 302 ? -0.552  -39.581 16.541  1.00 28.11  ? 302 THR B O   1 
ATOM   5308  C CB  . THR B 1 302 ? 0.671   -41.523 18.993  1.00 32.86  ? 302 THR B CB  1 
ATOM   5309  O OG1 . THR B 1 302 ? 0.782   -41.778 20.394  1.00 39.30  ? 302 THR B OG1 1 
ATOM   5310  C CG2 . THR B 1 302 ? 1.947   -41.004 18.542  1.00 35.79  ? 302 THR B CG2 1 
ATOM   5311  N N   . LEU B 1 303 ? -1.525  -41.576 16.946  1.00 30.84  ? 303 LEU B N   1 
ATOM   5312  C CA  . LEU B 1 303 ? -1.952  -41.824 15.572  1.00 29.27  ? 303 LEU B CA  1 
ATOM   5313  C C   . LEU B 1 303 ? -2.852  -40.723 15.038  1.00 28.16  ? 303 LEU B C   1 
ATOM   5314  O O   . LEU B 1 303 ? -2.733  -40.326 13.875  1.00 30.76  ? 303 LEU B O   1 
ATOM   5315  C CB  . LEU B 1 303 ? -2.708  -43.145 15.517  1.00 28.73  ? 303 LEU B CB  1 
ATOM   5316  C CG  . LEU B 1 303 ? -2.006  -44.475 15.279  1.00 33.48  ? 303 LEU B CG  1 
ATOM   5317  C CD1 . LEU B 1 303 ? -0.537  -44.292 14.904  1.00 31.01  ? 303 LEU B CD1 1 
ATOM   5318  C CD2 . LEU B 1 303 ? -2.185  -45.330 16.523  1.00 30.38  ? 303 LEU B CD2 1 
ATOM   5319  N N   . LYS B 1 304 ? -3.801  -40.254 15.860  1.00 33.01  ? 304 LYS B N   1 
ATOM   5320  C CA  . LYS B 1 304 ? -4.808  -39.313 15.366  1.00 34.29  ? 304 LYS B CA  1 
ATOM   5321  C C   . LYS B 1 304 ? -4.209  -37.957 15.018  1.00 27.72  ? 304 LYS B C   1 
ATOM   5322  O O   . LYS B 1 304 ? -4.422  -37.490 13.888  1.00 30.81  ? 304 LYS B O   1 
ATOM   5323  C CB  . LYS B 1 304 ? -5.955  -39.202 16.379  1.00 31.81  ? 304 LYS B CB  1 
ATOM   5324  C CG  . LYS B 1 304 ? -7.199  -38.418 15.945  1.00 36.57  ? 304 LYS B CG  1 
ATOM   5325  C CD  . LYS B 1 304 ? -7.697  -37.547 17.122  1.00 44.53  ? 304 LYS B CD  1 
ATOM   5326  C CE  . LYS B 1 304 ? -9.211  -37.319 17.131  1.00 47.13  ? 304 LYS B CE  1 
ATOM   5327  N NZ  . LYS B 1 304 ? -9.831  -37.385 15.789  1.00 51.35  ? 304 LYS B NZ  1 
ATOM   5328  N N   . PRO B 1 305 ? -3.453  -37.285 15.890  1.00 27.16  ? 305 PRO B N   1 
ATOM   5329  C CA  . PRO B 1 305 ? -2.853  -36.012 15.452  1.00 27.28  ? 305 PRO B CA  1 
ATOM   5330  C C   . PRO B 1 305 ? -1.848  -36.190 14.320  1.00 29.18  ? 305 PRO B C   1 
ATOM   5331  O O   . PRO B 1 305 ? -1.793  -35.337 13.425  1.00 24.25  ? 305 PRO B O   1 
ATOM   5332  C CB  . PRO B 1 305 ? -2.195  -35.457 16.728  1.00 24.86  ? 305 PRO B CB  1 
ATOM   5333  C CG  . PRO B 1 305 ? -2.712  -36.288 17.856  1.00 32.28  ? 305 PRO B CG  1 
ATOM   5334  C CD  . PRO B 1 305 ? -3.053  -37.632 17.266  1.00 33.04  ? 305 PRO B CD  1 
ATOM   5335  N N   . ALA B 1 306 ? -1.068  -37.283 14.315  1.00 30.73  ? 306 ALA B N   1 
ATOM   5336  C CA  . ALA B 1 306 ? -0.172  -37.550 13.186  1.00 29.88  ? 306 ALA B CA  1 
ATOM   5337  C C   . ALA B 1 306 ? -0.962  -37.703 11.892  1.00 27.83  ? 306 ALA B C   1 
ATOM   5338  O O   . ALA B 1 306 ? -0.624  -37.095 10.866  1.00 26.34  ? 306 ALA B O   1 
ATOM   5339  C CB  . ALA B 1 306 ? 0.669   -38.805 13.447  1.00 26.36  ? 306 ALA B CB  1 
ATOM   5340  N N   . GLU B 1 307 ? -2.030  -38.509 11.931  1.00 27.95  ? 307 GLU B N   1 
ATOM   5341  C CA  . GLU B 1 307 ? -2.864  -38.705 10.745  1.00 29.05  ? 307 GLU B CA  1 
ATOM   5342  C C   . GLU B 1 307 ? -3.446  -37.380 10.259  1.00 26.08  ? 307 GLU B C   1 
ATOM   5343  O O   . GLU B 1 307 ? -3.575  -37.157 9.050   1.00 26.04  ? 307 GLU B O   1 
ATOM   5344  C CB  . GLU B 1 307 ? -3.987  -39.716 11.034  1.00 26.63  ? 307 GLU B CB  1 
ATOM   5345  C CG  . GLU B 1 307 ? -5.146  -39.682 10.006  1.00 31.41  ? 307 GLU B CG  1 
ATOM   5346  C CD  . GLU B 1 307 ? -6.359  -40.543 10.377  1.00 36.41  ? 307 GLU B CD  1 
ATOM   5347  O OE1 . GLU B 1 307 ? -6.913  -40.436 11.498  1.00 39.67  ? 307 GLU B OE1 1 
ATOM   5348  O OE2 . GLU B 1 307 ? -6.762  -41.349 9.522   1.00 47.41  ? 307 GLU B OE2 1 
ATOM   5349  N N   . GLU B 1 308 ? -3.785  -36.482 11.188  1.00 22.86  ? 308 GLU B N   1 
ATOM   5350  C CA  . GLU B 1 308 ? -4.363  -35.197 10.806  1.00 27.73  ? 308 GLU B CA  1 
ATOM   5351  C C   . GLU B 1 308 ? -3.342  -34.338 10.073  1.00 25.49  ? 308 GLU B C   1 
ATOM   5352  O O   . GLU B 1 308 ? -3.614  -33.821 8.982   1.00 21.17  ? 308 GLU B O   1 
ATOM   5353  C CB  . GLU B 1 308 ? -4.881  -34.471 12.045  1.00 30.46  ? 308 GLU B CB  1 
ATOM   5354  C CG  . GLU B 1 308 ? -6.297  -34.850 12.461  1.00 37.63  ? 308 GLU B CG  1 
ATOM   5355  C CD  . GLU B 1 308 ? -7.273  -33.694 12.273  1.00 48.37  ? 308 GLU B CD  1 
ATOM   5356  O OE1 . GLU B 1 308 ? -8.503  -33.932 12.332  1.00 55.03  ? 308 GLU B OE1 1 
ATOM   5357  O OE2 . GLU B 1 308 ? -6.803  -32.541 12.095  1.00 51.19  ? 308 GLU B OE2 1 
ATOM   5358  N N   . PHE B 1 309 ? -2.150  -34.190 10.662  1.00 21.63  ? 309 PHE B N   1 
ATOM   5359  C CA  . PHE B 1 309 ? -1.084  -33.418 10.031  1.00 19.72  ? 309 PHE B CA  1 
ATOM   5360  C C   . PHE B 1 309 ? -0.727  -33.982 8.662   1.00 25.72  ? 309 PHE B C   1 
ATOM   5361  O O   . PHE B 1 309 ? -0.533  -33.227 7.701   1.00 24.71  ? 309 PHE B O   1 
ATOM   5362  C CB  . PHE B 1 309 ? 0.151   -33.401 10.934  1.00 22.81  ? 309 PHE B CB  1 
ATOM   5363  C CG  . PHE B 1 309 ? 1.199   -32.437 10.480  1.00 21.70  ? 309 PHE B CG  1 
ATOM   5364  C CD1 . PHE B 1 309 ? 2.106   -32.787 9.485   1.00 21.54  ? 309 PHE B CD1 1 
ATOM   5365  C CD2 . PHE B 1 309 ? 1.262   -31.178 11.024  1.00 19.30  ? 309 PHE B CD2 1 
ATOM   5366  C CE1 . PHE B 1 309 ? 3.032   -31.893 9.049   1.00 19.59  ? 309 PHE B CE1 1 
ATOM   5367  C CE2 . PHE B 1 309 ? 2.205   -30.275 10.588  1.00 24.95  ? 309 PHE B CE2 1 
ATOM   5368  C CZ  . PHE B 1 309 ? 3.082   -30.633 9.591   1.00 21.88  ? 309 PHE B CZ  1 
ATOM   5369  N N   . ILE B 1 310 ? -0.630  -35.312 8.559   1.00 24.80  ? 310 ILE B N   1 
ATOM   5370  C CA  . ILE B 1 310 ? -0.183  -35.933 7.319   1.00 23.71  ? 310 ILE B CA  1 
ATOM   5371  C C   . ILE B 1 310 ? -1.236  -35.752 6.236   1.00 25.95  ? 310 ILE B C   1 
ATOM   5372  O O   . ILE B 1 310 ? -0.914  -35.523 5.061   1.00 27.14  ? 310 ILE B O   1 
ATOM   5373  C CB  . ILE B 1 310 ? 0.146   -37.416 7.570   1.00 23.59  ? 310 ILE B CB  1 
ATOM   5374  C CG1 . ILE B 1 310 ? 1.374   -37.546 8.483   1.00 25.58  ? 310 ILE B CG1 1 
ATOM   5375  C CG2 . ILE B 1 310 ? 0.384   -38.153 6.264   1.00 29.94  ? 310 ILE B CG2 1 
ATOM   5376  C CD1 . ILE B 1 310 ? 2.697   -37.154 7.835   1.00 19.96  ? 310 ILE B CD1 1 
ATOM   5377  N N   . GLU B 1 311 ? -2.508  -35.835 6.618   1.00 25.30  ? 311 GLU B N   1 
ATOM   5378  C CA  . GLU B 1 311 ? -3.594  -35.588 5.682   1.00 24.52  ? 311 GLU B CA  1 
ATOM   5379  C C   . GLU B 1 311 ? -3.522  -34.179 5.134   1.00 24.55  ? 311 GLU B C   1 
ATOM   5380  O O   . GLU B 1 311 ? -3.841  -33.939 3.964   1.00 29.91  ? 311 GLU B O   1 
ATOM   5381  C CB  . GLU B 1 311 ? -4.943  -35.823 6.372   1.00 24.91  ? 311 GLU B CB  1 
ATOM   5382  C CG  . GLU B 1 311 ? -6.087  -36.129 5.433   1.00 30.30  ? 311 GLU B CG  1 
ATOM   5383  C CD  . GLU B 1 311 ? -5.759  -37.247 4.446   1.00 35.69  ? 311 GLU B CD  1 
ATOM   5384  O OE1 . GLU B 1 311 ? -5.199  -38.286 4.888   1.00 34.51  ? 311 GLU B OE1 1 
ATOM   5385  O OE2 . GLU B 1 311 ? -6.081  -37.084 3.243   1.00 28.73  ? 311 GLU B OE2 1 
ATOM   5386  N N   . MET B 1 312 ? -3.098  -33.232 5.958   1.00 23.45  ? 312 MET B N   1 
ATOM   5387  C CA  . MET B 1 312 ? -2.934  -31.881 5.456   1.00 23.31  ? 312 MET B CA  1 
ATOM   5388  C C   . MET B 1 312 ? -1.719  -31.780 4.537   1.00 23.41  ? 312 MET B C   1 
ATOM   5389  O O   . MET B 1 312 ? -1.734  -30.996 3.581   1.00 20.88  ? 312 MET B O   1 
ATOM   5390  C CB  . MET B 1 312 ? -2.831  -30.923 6.635   1.00 23.69  ? 312 MET B CB  1 
ATOM   5391  C CG  . MET B 1 312 ? -3.002  -29.469 6.274   1.00 29.17  ? 312 MET B CG  1 
ATOM   5392  S SD  . MET B 1 312 ? -1.815  -28.565 7.255   1.00 44.87  ? 312 MET B SD  1 
ATOM   5393  C CE  . MET B 1 312 ? -0.332  -29.332 6.593   1.00 23.09  ? 312 MET B CE  1 
ATOM   5394  N N   . ILE B 1 313 ? -0.671  -32.573 4.801   1.00 21.16  ? 313 ILE B N   1 
ATOM   5395  C CA  . ILE B 1 313 ? 0.455   -32.660 3.872   1.00 23.51  ? 313 ILE B CA  1 
ATOM   5396  C C   . ILE B 1 313 ? -0.034  -33.152 2.518   1.00 19.03  ? 313 ILE B C   1 
ATOM   5397  O O   . ILE B 1 313 ? 0.302   -32.594 1.473   1.00 20.61  ? 313 ILE B O   1 
ATOM   5398  C CB  . ILE B 1 313 ? 1.559   -33.585 4.432   1.00 21.57  ? 313 ILE B CB  1 
ATOM   5399  C CG1 . ILE B 1 313 ? 2.286   -32.956 5.616   1.00 19.07  ? 313 ILE B CG1 1 
ATOM   5400  C CG2 . ILE B 1 313 ? 2.556   -33.890 3.378   1.00 23.36  ? 313 ILE B CG2 1 
ATOM   5401  C CD1 . ILE B 1 313 ? 2.943   -31.657 5.278   1.00 24.07  ? 313 ILE B CD1 1 
ATOM   5402  N N   . ARG B 1 314 ? -0.839  -34.210 2.528   1.00 21.05  ? 314 ARG B N   1 
ATOM   5403  C CA  . ARG B 1 314 ? -1.415  -34.737 1.297   1.00 24.99  ? 314 ARG B CA  1 
ATOM   5404  C C   . ARG B 1 314 ? -2.271  -33.687 0.586   1.00 26.42  ? 314 ARG B C   1 
ATOM   5405  O O   . ARG B 1 314 ? -2.172  -33.515 -0.638  1.00 22.43  ? 314 ARG B O   1 
ATOM   5406  C CB  . ARG B 1 314 ? -2.252  -35.979 1.614   1.00 19.57  ? 314 ARG B CB  1 
ATOM   5407  C CG  . ARG B 1 314 ? -2.512  -36.899 0.422   1.00 25.29  ? 314 ARG B CG  1 
ATOM   5408  C CD  . ARG B 1 314 ? -3.241  -38.180 0.863   1.00 25.16  ? 314 ARG B CD  1 
ATOM   5409  N NE  . ARG B 1 314 ? -4.628  -37.886 1.188   1.00 25.26  ? 314 ARG B NE  1 
ATOM   5410  C CZ  . ARG B 1 314 ? -5.587  -37.700 0.289   1.00 28.40  ? 314 ARG B CZ  1 
ATOM   5411  N NH1 . ARG B 1 314 ? -5.363  -37.849 -1.005  1.00 31.57  ? 314 ARG B NH1 1 
ATOM   5412  N NH2 . ARG B 1 314 ? -6.797  -37.352 0.697   1.00 25.77  ? 314 ARG B NH2 1 
ATOM   5413  N N   . THR B 1 315 ? -3.127  -32.988 1.337   1.00 22.59  ? 315 THR B N   1 
ATOM   5414  C CA  . THR B 1 315 ? -3.958  -31.936 0.745   1.00 23.12  ? 315 THR B CA  1 
ATOM   5415  C C   . THR B 1 315 ? -3.097  -30.888 0.033   1.00 26.18  ? 315 THR B C   1 
ATOM   5416  O O   . THR B 1 315 ? -3.457  -30.398 -1.046  1.00 25.78  ? 315 THR B O   1 
ATOM   5417  C CB  . THR B 1 315 ? -4.816  -31.288 1.841   1.00 26.63  ? 315 THR B CB  1 
ATOM   5418  O OG1 . THR B 1 315 ? -5.718  -32.264 2.376   1.00 30.97  ? 315 THR B OG1 1 
ATOM   5419  C CG2 . THR B 1 315 ? -5.628  -30.081 1.301   1.00 26.46  ? 315 THR B CG2 1 
ATOM   5420  N N   . ILE B 1 316 ? -1.945  -30.547 0.617   1.00 21.71  ? 316 ILE B N   1 
ATOM   5421  C CA  . ILE B 1 316 ? -1.046  -29.568 0.019   1.00 18.35  ? 316 ILE B CA  1 
ATOM   5422  C C   . ILE B 1 316 ? -0.520  -30.059 -1.328  1.00 29.12  ? 316 ILE B C   1 
ATOM   5423  O O   . ILE B 1 316 ? -0.240  -29.256 -2.224  1.00 27.58  ? 316 ILE B O   1 
ATOM   5424  C CB  . ILE B 1 316 ? 0.102   -29.261 1.003   1.00 22.46  ? 316 ILE B CB  1 
ATOM   5425  C CG1 . ILE B 1 316 ? -0.378  -28.359 2.154   1.00 29.50  ? 316 ILE B CG1 1 
ATOM   5426  C CG2 . ILE B 1 316 ? 1.270   -28.587 0.298   1.00 23.16  ? 316 ILE B CG2 1 
ATOM   5427  C CD1 . ILE B 1 316 ? 0.671   -28.174 3.262   1.00 22.75  ? 316 ILE B CD1 1 
ATOM   5428  N N   . GLY B 1 317 ? -0.385  -31.375 -1.502  1.00 25.65  ? 317 GLY B N   1 
ATOM   5429  C CA  . GLY B 1 317 ? 0.044   -31.897 -2.782  1.00 22.70  ? 317 GLY B CA  1 
ATOM   5430  C C   . GLY B 1 317 ? 1.184   -32.904 -2.744  1.00 25.09  ? 317 GLY B C   1 
ATOM   5431  O O   . GLY B 1 317 ? 1.513   -33.480 -3.776  1.00 25.95  ? 317 GLY B O   1 
ATOM   5432  N N   . TYR B 1 318 ? 1.800   -33.153 -1.595  1.00 22.38  ? 318 TYR B N   1 
ATOM   5433  C CA  . TYR B 1 318 ? 2.878   -34.121 -1.583  1.00 23.12  ? 318 TYR B CA  1 
ATOM   5434  C C   . TYR B 1 318 ? 2.350   -35.516 -1.879  1.00 23.61  ? 318 TYR B C   1 
ATOM   5435  O O   . TYR B 1 318 ? 1.351   -35.964 -1.300  1.00 21.11  ? 318 TYR B O   1 
ATOM   5436  C CB  . TYR B 1 318 ? 3.601   -34.128 -0.251  1.00 24.57  ? 318 TYR B CB  1 
ATOM   5437  C CG  . TYR B 1 318 ? 4.755   -35.083 -0.272  1.00 22.02  ? 318 TYR B CG  1 
ATOM   5438  C CD1 . TYR B 1 318 ? 5.899   -34.799 -0.999  1.00 25.58  ? 318 TYR B CD1 1 
ATOM   5439  C CD2 . TYR B 1 318 ? 4.692   -36.288 0.401   1.00 25.04  ? 318 TYR B CD2 1 
ATOM   5440  C CE1 . TYR B 1 318 ? 6.974   -35.689 -1.025  1.00 23.85  ? 318 TYR B CE1 1 
ATOM   5441  C CE2 . TYR B 1 318 ? 5.762   -37.180 0.383   1.00 23.40  ? 318 TYR B CE2 1 
ATOM   5442  C CZ  . TYR B 1 318 ? 6.895   -36.870 -0.329  1.00 23.52  ? 318 TYR B CZ  1 
ATOM   5443  O OH  . TYR B 1 318 ? 7.946   -37.758 -0.362  1.00 24.70  ? 318 TYR B OH  1 
ATOM   5444  N N   . ARG B 1 319 ? 3.018   -36.186 -2.801  1.00 23.80  ? 319 ARG B N   1 
ATOM   5445  C CA  . ARG B 1 319 ? 2.768   -37.576 -3.141  1.00 27.72  ? 319 ARG B CA  1 
ATOM   5446  C C   . ARG B 1 319 ? 4.068   -38.343 -2.954  1.00 25.29  ? 319 ARG B C   1 
ATOM   5447  O O   . ARG B 1 319 ? 5.121   -37.903 -3.419  1.00 25.30  ? 319 ARG B O   1 
ATOM   5448  C CB  . ARG B 1 319 ? 2.282   -37.714 -4.583  1.00 25.85  ? 319 ARG B CB  1 
ATOM   5449  C CG  . ARG B 1 319 ? 1.119   -36.825 -4.931  1.00 25.11  ? 319 ARG B CG  1 
ATOM   5450  C CD  . ARG B 1 319 ? -0.134  -37.337 -4.284  1.00 24.62  ? 319 ARG B CD  1 
ATOM   5451  N NE  . ARG B 1 319 ? -1.296  -36.469 -4.483  1.00 26.43  ? 319 ARG B NE  1 
ATOM   5452  C CZ  . ARG B 1 319 ? -1.748  -35.612 -3.576  1.00 24.73  ? 319 ARG B CZ  1 
ATOM   5453  N NH1 . ARG B 1 319 ? -1.089  -35.381 -2.455  1.00 24.88  ? 319 ARG B NH1 1 
ATOM   5454  N NH2 . ARG B 1 319 ? -2.897  -34.982 -3.791  1.00 23.47  ? 319 ARG B NH2 1 
ATOM   5455  N N   . GLY B 1 320 ? 3.990   -39.488 -2.278  1.00 29.24  ? 320 GLY B N   1 
ATOM   5456  C CA  . GLY B 1 320 ? 5.167   -40.274 -1.952  1.00 24.56  ? 320 GLY B CA  1 
ATOM   5457  C C   . GLY B 1 320 ? 5.244   -40.666 -0.485  1.00 25.78  ? 320 GLY B C   1 
ATOM   5458  O O   . GLY B 1 320 ? 4.224   -40.707 0.210   1.00 22.88  ? 320 GLY B O   1 
ATOM   5459  N N   . TYR B 1 321 ? 6.456   -40.947 -0.006  1.00 24.63  ? 321 TYR B N   1 
ATOM   5460  C CA  . TYR B 1 321 ? 6.691   -41.373 1.366   1.00 19.42  ? 321 TYR B CA  1 
ATOM   5461  C C   . TYR B 1 321 ? 7.006   -40.182 2.259   1.00 21.58  ? 321 TYR B C   1 
ATOM   5462  O O   . TYR B 1 321 ? 7.787   -39.302 1.884   1.00 24.79  ? 321 TYR B O   1 
ATOM   5463  C CB  . TYR B 1 321 ? 7.852   -42.364 1.412   1.00 22.72  ? 321 TYR B CB  1 
ATOM   5464  C CG  . TYR B 1 321 ? 7.553   -43.616 0.646   1.00 23.21  ? 321 TYR B CG  1 
ATOM   5465  C CD1 . TYR B 1 321 ? 6.786   -44.614 1.232   1.00 23.57  ? 321 TYR B CD1 1 
ATOM   5466  C CD2 . TYR B 1 321 ? 7.981   -43.792 -0.666  1.00 21.43  ? 321 TYR B CD2 1 
ATOM   5467  C CE1 . TYR B 1 321 ? 6.476   -45.760 0.564   1.00 22.50  ? 321 TYR B CE1 1 
ATOM   5468  C CE2 . TYR B 1 321 ? 7.664   -44.964 -1.359  1.00 21.79  ? 321 TYR B CE2 1 
ATOM   5469  C CZ  . TYR B 1 321 ? 6.914   -45.949 -0.711  1.00 26.82  ? 321 TYR B CZ  1 
ATOM   5470  O OH  . TYR B 1 321 ? 6.548   -47.138 -1.308  1.00 28.76  ? 321 TYR B OH  1 
ATOM   5471  N N   . VAL B 1 322 ? 6.414   -40.173 3.453   1.00 21.62  ? 322 VAL B N   1 
ATOM   5472  C CA  . VAL B 1 322 ? 6.645   -39.104 4.422   1.00 23.79  ? 322 VAL B CA  1 
ATOM   5473  C C   . VAL B 1 322 ? 6.609   -39.710 5.819   1.00 20.84  ? 322 VAL B C   1 
ATOM   5474  O O   . VAL B 1 322 ? 5.886   -40.672 6.073   1.00 22.27  ? 322 VAL B O   1 
ATOM   5475  C CB  . VAL B 1 322 ? 5.616   -37.960 4.260   1.00 20.76  ? 322 VAL B CB  1 
ATOM   5476  C CG1 . VAL B 1 322 ? 4.198   -38.477 4.474   1.00 16.35  ? 322 VAL B CG1 1 
ATOM   5477  C CG2 . VAL B 1 322 ? 5.922   -36.838 5.227   1.00 21.18  ? 322 VAL B CG2 1 
ATOM   5478  N N   . ASN B 1 323 ? 7.436   -39.193 6.716   1.00 22.50  ? 323 ASN B N   1 
ATOM   5479  C CA  . ASN B 1 323 ? 7.438   -39.708 8.073   1.00 23.38  ? 323 ASN B CA  1 
ATOM   5480  C C   . ASN B 1 323 ? 7.379   -38.545 9.051   1.00 23.67  ? 323 ASN B C   1 
ATOM   5481  O O   . ASN B 1 323 ? 7.707   -37.418 8.705   1.00 19.28  ? 323 ASN B O   1 
ATOM   5482  C CB  . ASN B 1 323 ? 8.657   -40.605 8.349   1.00 21.39  ? 323 ASN B CB  1 
ATOM   5483  C CG  . ASN B 1 323 ? 9.964   -39.924 8.060   1.00 24.50  ? 323 ASN B CG  1 
ATOM   5484  O OD1 . ASN B 1 323 ? 10.573  -39.342 8.948   1.00 28.32  ? 323 ASN B OD1 1 
ATOM   5485  N ND2 . ASN B 1 323 ? 10.411  -40.001 6.818   1.00 27.83  ? 323 ASN B ND2 1 
ATOM   5486  N N   . ILE B 1 324 ? 6.947   -38.826 10.282  1.00 22.64  ? 324 ILE B N   1 
ATOM   5487  C CA  . ILE B 1 324 ? 6.803   -37.790 11.298  1.00 24.08  ? 324 ILE B CA  1 
ATOM   5488  C C   . ILE B 1 324 ? 7.337   -38.324 12.627  1.00 22.31  ? 324 ILE B C   1 
ATOM   5489  O O   . ILE B 1 324 ? 6.997   -39.436 13.039  1.00 19.79  ? 324 ILE B O   1 
ATOM   5490  C CB  . ILE B 1 324 ? 5.335   -37.319 11.402  1.00 20.83  ? 324 ILE B CB  1 
ATOM   5491  C CG1 . ILE B 1 324 ? 5.167   -36.212 12.441  1.00 25.64  ? 324 ILE B CG1 1 
ATOM   5492  C CG2 . ILE B 1 324 ? 4.411   -38.486 11.679  1.00 24.79  ? 324 ILE B CG2 1 
ATOM   5493  C CD1 . ILE B 1 324 ? 3.790   -35.563 12.451  1.00 24.96  ? 324 ILE B CD1 1 
ATOM   5494  N N   . ASP B 1 325 ? 8.204   -37.542 13.268  1.00 20.93  ? 325 ASP B N   1 
ATOM   5495  C CA  . ASP B 1 325 ? 8.882   -37.883 14.511  1.00 27.41  ? 325 ASP B CA  1 
ATOM   5496  C C   . ASP B 1 325 ? 8.091   -37.386 15.714  1.00 25.06  ? 325 ASP B C   1 
ATOM   5497  O O   . ASP B 1 325 ? 7.450   -36.334 15.665  1.00 26.81  ? 325 ASP B O   1 
ATOM   5498  C CB  . ASP B 1 325 ? 10.264  -37.224 14.563  1.00 32.04  ? 325 ASP B CB  1 
ATOM   5499  C CG  . ASP B 1 325 ? 11.322  -38.028 13.885  1.00 45.76  ? 325 ASP B CG  1 
ATOM   5500  O OD1 . ASP B 1 325 ? 11.619  -39.145 14.372  1.00 48.66  ? 325 ASP B OD1 1 
ATOM   5501  O OD2 . ASP B 1 325 ? 11.869  -37.532 12.866  1.00 52.19  ? 325 ASP B OD2 1 
ATOM   5502  N N   . GLY B 1 326 ? 8.210   -38.098 16.827  1.00 23.05  ? 326 GLY B N   1 
ATOM   5503  C CA  . GLY B 1 326 ? 7.531   -37.634 18.014  1.00 26.81  ? 326 GLY B CA  1 
ATOM   5504  C C   . GLY B 1 326 ? 8.051   -38.282 19.274  1.00 31.25  ? 326 GLY B C   1 
ATOM   5505  O O   . GLY B 1 326 ? 8.876   -39.195 19.241  1.00 28.33  ? 326 GLY B O   1 
ATOM   5506  N N   . ILE B 1 327 ? 7.541   -37.789 20.400  1.00 28.37  ? 327 ILE B N   1 
ATOM   5507  C CA  . ILE B 1 327 ? 7.955   -38.243 21.713  1.00 30.55  ? 327 ILE B CA  1 
ATOM   5508  C C   . ILE B 1 327 ? 6.734   -38.298 22.616  1.00 32.55  ? 327 ILE B C   1 
ATOM   5509  O O   . ILE B 1 327 ? 5.794   -37.506 22.482  1.00 26.02  ? 327 ILE B O   1 
ATOM   5510  C CB  . ILE B 1 327 ? 9.026   -37.324 22.347  1.00 31.96  ? 327 ILE B CB  1 
ATOM   5511  C CG1 . ILE B 1 327 ? 8.571   -35.860 22.304  1.00 32.80  ? 327 ILE B CG1 1 
ATOM   5512  C CG2 . ILE B 1 327 ? 10.372  -37.506 21.682  1.00 29.61  ? 327 ILE B CG2 1 
ATOM   5513  C CD1 . ILE B 1 327 ? 9.390   -34.943 23.199  1.00 28.62  ? 327 ILE B CD1 1 
ATOM   5514  N N   . VAL B 1 328 ? 6.766   -39.226 23.560  1.00 31.21  ? 328 VAL B N   1 
ATOM   5515  C CA  . VAL B 1 328 ? 5.769   -39.304 24.617  1.00 36.15  ? 328 VAL B CA  1 
ATOM   5516  C C   . VAL B 1 328 ? 6.493   -39.157 25.950  1.00 37.72  ? 328 VAL B C   1 
ATOM   5517  O O   . VAL B 1 328 ? 7.424   -39.920 26.244  1.00 38.26  ? 328 VAL B O   1 
ATOM   5518  C CB  . VAL B 1 328 ? 4.987   -40.621 24.557  1.00 40.22  ? 328 VAL B CB  1 
ATOM   5519  C CG1 . VAL B 1 328 ? 4.234   -40.836 25.864  1.00 46.58  ? 328 VAL B CG1 1 
ATOM   5520  C CG2 . VAL B 1 328 ? 4.045   -40.622 23.346  1.00 38.22  ? 328 VAL B CG2 1 
ATOM   5521  N N   . LEU B 1 329 ? 6.071   -38.181 26.752  1.00 38.22  ? 329 LEU B N   1 
ATOM   5522  C CA  . LEU B 1 329 ? 6.661   -38.001 28.070  1.00 40.22  ? 329 LEU B CA  1 
ATOM   5523  C C   . LEU B 1 329 ? 6.035   -38.955 29.084  1.00 40.20  ? 329 LEU B C   1 
ATOM   5524  O O   . LEU B 1 329 ? 4.987   -39.568 28.849  1.00 36.96  ? 329 LEU B O   1 
ATOM   5525  C CB  . LEU B 1 329 ? 6.502   -36.561 28.551  1.00 38.17  ? 329 LEU B CB  1 
ATOM   5526  C CG  . LEU B 1 329 ? 6.866   -35.424 27.602  1.00 39.23  ? 329 LEU B CG  1 
ATOM   5527  C CD1 . LEU B 1 329 ? 6.604   -34.093 28.279  1.00 35.24  ? 329 LEU B CD1 1 
ATOM   5528  C CD2 . LEU B 1 329 ? 8.321   -35.521 27.172  1.00 39.10  ? 329 LEU B CD2 1 
ATOM   5529  N N   . ASP B 1 330 ? 6.700   -39.058 30.237  1.00 42.66  ? 330 ASP B N   1 
ATOM   5530  C CA  . ASP B 1 330 ? 6.203   -39.881 31.335  1.00 44.88  ? 330 ASP B CA  1 
ATOM   5531  C C   . ASP B 1 330 ? 4.778   -39.518 31.733  1.00 46.04  ? 330 ASP B C   1 
ATOM   5532  O O   . ASP B 1 330 ? 4.007   -40.397 32.137  1.00 40.89  ? 330 ASP B O   1 
ATOM   5533  C CB  . ASP B 1 330 ? 7.131   -39.746 32.543  1.00 49.60  ? 330 ASP B CB  1 
ATOM   5534  C CG  . ASP B 1 330 ? 8.388   -40.577 32.406  1.00 53.28  ? 330 ASP B CG  1 
ATOM   5535  O OD1 . ASP B 1 330 ? 8.444   -41.416 31.480  1.00 55.46  ? 330 ASP B OD1 1 
ATOM   5536  O OD2 . ASP B 1 330 ? 9.318   -40.392 33.225  1.00 60.16  ? 330 ASP B OD2 1 
ATOM   5537  N N   . ASP B 1 331 ? 4.410   -38.234 31.621  1.00 43.97  ? 331 ASP B N   1 
ATOM   5538  C CA  . ASP B 1 331 ? 3.092   -37.753 32.031  1.00 38.71  ? 331 ASP B CA  1 
ATOM   5539  C C   . ASP B 1 331 ? 2.002   -38.010 31.002  1.00 42.39  ? 331 ASP B C   1 
ATOM   5540  O O   . ASP B 1 331 ? 0.836   -37.711 31.277  1.00 45.31  ? 331 ASP B O   1 
ATOM   5541  C CB  . ASP B 1 331 ? 3.132   -36.245 32.335  1.00 42.36  ? 331 ASP B CB  1 
ATOM   5542  C CG  . ASP B 1 331 ? 3.684   -35.408 31.168  1.00 43.37  ? 331 ASP B CG  1 
ATOM   5543  O OD1 . ASP B 1 331 ? 3.452   -35.752 29.990  1.00 42.53  ? 331 ASP B OD1 1 
ATOM   5544  O OD2 . ASP B 1 331 ? 4.342   -34.378 31.431  1.00 50.68  ? 331 ASP B OD2 1 
ATOM   5545  N N   . GLY B 1 332 ? 2.344   -38.505 29.815  1.00 45.99  ? 332 GLY B N   1 
ATOM   5546  C CA  . GLY B 1 332 ? 1.354   -38.782 28.795  1.00 41.46  ? 332 GLY B CA  1 
ATOM   5547  C C   . GLY B 1 332 ? 1.233   -37.748 27.696  1.00 38.79  ? 332 GLY B C   1 
ATOM   5548  O O   . GLY B 1 332 ? 0.447   -37.960 26.762  1.00 39.89  ? 332 GLY B O   1 
ATOM   5549  N N   . ARG B 1 333 ? 1.975   -36.646 27.776  1.00 33.88  ? 333 ARG B N   1 
ATOM   5550  C CA  . ARG B 1 333 ? 1.936   -35.612 26.748  1.00 35.18  ? 333 ARG B CA  1 
ATOM   5551  C C   . ARG B 1 333 ? 2.701   -36.049 25.498  1.00 39.39  ? 333 ARG B C   1 
ATOM   5552  O O   . ARG B 1 333 ? 3.803   -36.601 25.580  1.00 36.64  ? 333 ARG B O   1 
ATOM   5553  C CB  . ARG B 1 333 ? 2.529   -34.311 27.286  1.00 35.60  ? 333 ARG B CB  1 
ATOM   5554  C CG  . ARG B 1 333 ? 1.717   -33.634 28.386  1.00 30.29  ? 333 ARG B CG  1 
ATOM   5555  C CD  . ARG B 1 333 ? 2.400   -32.354 28.815  1.00 36.47  ? 333 ARG B CD  1 
ATOM   5556  N NE  . ARG B 1 333 ? 3.589   -32.628 29.612  1.00 40.69  ? 333 ARG B NE  1 
ATOM   5557  C CZ  . ARG B 1 333 ? 4.583   -31.771 29.780  1.00 37.80  ? 333 ARG B CZ  1 
ATOM   5558  N NH1 . ARG B 1 333 ? 4.581   -30.595 29.181  1.00 36.98  ? 333 ARG B NH1 1 
ATOM   5559  N NH2 . ARG B 1 333 ? 5.602   -32.103 30.575  1.00 36.84  ? 333 ARG B NH2 1 
ATOM   5560  N N   . VAL B 1 334 ? 2.111   -35.785 24.342  1.00 32.76  ? 334 VAL B N   1 
ATOM   5561  C CA  . VAL B 1 334 ? 2.695   -36.089 23.043  1.00 30.02  ? 334 VAL B CA  1 
ATOM   5562  C C   . VAL B 1 334 ? 3.256   -34.812 22.449  1.00 30.68  ? 334 VAL B C   1 
ATOM   5563  O O   . VAL B 1 334 ? 2.653   -33.741 22.581  1.00 29.33  ? 334 VAL B O   1 
ATOM   5564  C CB  . VAL B 1 334 ? 1.638   -36.699 22.101  1.00 32.50  ? 334 VAL B CB  1 
ATOM   5565  C CG1 . VAL B 1 334 ? 2.223   -36.961 20.707  1.00 28.31  ? 334 VAL B CG1 1 
ATOM   5566  C CG2 . VAL B 1 334 ? 1.056   -37.975 22.700  1.00 34.68  ? 334 VAL B CG2 1 
ATOM   5567  N N   . PHE B 1 335 ? 4.404   -34.914 21.780  1.00 27.18  ? 335 PHE B N   1 
ATOM   5568  C CA  . PHE B 1 335 ? 4.858   -33.847 20.901  1.00 29.88  ? 335 PHE B CA  1 
ATOM   5569  C C   . PHE B 1 335 ? 5.390   -34.468 19.621  1.00 29.57  ? 335 PHE B C   1 
ATOM   5570  O O   . PHE B 1 335 ? 5.942   -35.568 19.632  1.00 32.27  ? 335 PHE B O   1 
ATOM   5571  C CB  . PHE B 1 335 ? 5.951   -32.970 21.529  1.00 33.76  ? 335 PHE B CB  1 
ATOM   5572  C CG  . PHE B 1 335 ? 5.530   -32.276 22.786  1.00 34.69  ? 335 PHE B CG  1 
ATOM   5573  C CD1 . PHE B 1 335 ? 4.640   -31.210 22.746  1.00 37.12  ? 335 PHE B CD1 1 
ATOM   5574  C CD2 . PHE B 1 335 ? 6.030   -32.682 24.013  1.00 36.83  ? 335 PHE B CD2 1 
ATOM   5575  C CE1 . PHE B 1 335 ? 4.250   -30.569 23.920  1.00 38.44  ? 335 PHE B CE1 1 
ATOM   5576  C CE2 . PHE B 1 335 ? 5.649   -32.052 25.180  1.00 33.38  ? 335 PHE B CE2 1 
ATOM   5577  C CZ  . PHE B 1 335 ? 4.759   -30.992 25.133  1.00 36.84  ? 335 PHE B CZ  1 
ATOM   5578  N N   . PHE B 1 336 ? 5.210   -33.751 18.521  1.00 27.00  ? 336 PHE B N   1 
ATOM   5579  C CA  . PHE B 1 336 ? 5.801   -34.082 17.238  1.00 24.21  ? 336 PHE B CA  1 
ATOM   5580  C C   . PHE B 1 336 ? 6.879   -33.054 16.903  1.00 26.42  ? 336 PHE B C   1 
ATOM   5581  O O   . PHE B 1 336 ? 6.714   -31.865 17.177  1.00 29.04  ? 336 PHE B O   1 
ATOM   5582  C CB  . PHE B 1 336 ? 4.715   -34.142 16.158  1.00 27.29  ? 336 PHE B CB  1 
ATOM   5583  C CG  . PHE B 1 336 ? 3.690   -35.220 16.415  1.00 29.91  ? 336 PHE B CG  1 
ATOM   5584  C CD1 . PHE B 1 336 ? 3.941   -36.540 16.051  1.00 30.98  ? 336 PHE B CD1 1 
ATOM   5585  C CD2 . PHE B 1 336 ? 2.502   -34.929 17.059  1.00 27.74  ? 336 PHE B CD2 1 
ATOM   5586  C CE1 . PHE B 1 336 ? 3.011   -37.539 16.314  1.00 28.40  ? 336 PHE B CE1 1 
ATOM   5587  C CE2 . PHE B 1 336 ? 1.573   -35.922 17.320  1.00 26.36  ? 336 PHE B CE2 1 
ATOM   5588  C CZ  . PHE B 1 336 ? 1.821   -37.219 16.948  1.00 29.21  ? 336 PHE B CZ  1 
ATOM   5589  N N   . HIS B 1 337 ? 7.989   -33.521 16.325  1.00 27.11  ? 337 HIS B N   1 
ATOM   5590  C CA  . HIS B 1 337 ? 9.212   -32.733 16.142  1.00 33.17  ? 337 HIS B CA  1 
ATOM   5591  C C   . HIS B 1 337 ? 9.455   -32.283 14.711  1.00 27.88  ? 337 HIS B C   1 
ATOM   5592  O O   . HIS B 1 337 ? 9.881   -31.145 14.493  1.00 25.98  ? 337 HIS B O   1 
ATOM   5593  C CB  . HIS B 1 337 ? 10.441  -33.527 16.577  1.00 30.40  ? 337 HIS B CB  1 
ATOM   5594  C CG  . HIS B 1 337 ? 10.454  -33.880 18.023  1.00 32.95  ? 337 HIS B CG  1 
ATOM   5595  N ND1 . HIS B 1 337 ? 10.201  -32.954 19.014  1.00 43.16  ? 337 HIS B ND1 1 
ATOM   5596  C CD2 . HIS B 1 337 ? 10.731  -35.043 18.653  1.00 35.89  ? 337 HIS B CD2 1 
ATOM   5597  C CE1 . HIS B 1 337 ? 10.310  -33.536 20.194  1.00 39.60  ? 337 HIS B CE1 1 
ATOM   5598  N NE2 . HIS B 1 337 ? 10.623  -34.806 20.003  1.00 41.95  ? 337 HIS B NE2 1 
ATOM   5599  N N   . GLU B 1 338 ? 9.261   -33.165 13.732  1.00 25.90  ? 338 GLU B N   1 
ATOM   5600  C CA  . GLU B 1 338 ? 9.544   -32.792 12.353  1.00 28.98  ? 338 GLU B CA  1 
ATOM   5601  C C   . GLU B 1 338 ? 8.869   -33.786 11.425  1.00 27.00  ? 338 GLU B C   1 
ATOM   5602  O O   . GLU B 1 338 ? 8.316   -34.807 11.857  1.00 29.22  ? 338 GLU B O   1 
ATOM   5603  C CB  . GLU B 1 338 ? 11.069  -32.691 12.094  1.00 32.34  ? 338 GLU B CB  1 
ATOM   5604  C CG  . GLU B 1 338 ? 11.875  -33.995 12.065  1.00 31.47  ? 338 GLU B CG  1 
ATOM   5605  C CD  . GLU B 1 338 ? 13.389  -33.764 11.758  1.00 40.18  ? 338 GLU B CD  1 
ATOM   5606  O OE1 . GLU B 1 338 ? 14.040  -32.981 12.479  1.00 34.52  ? 338 GLU B OE1 1 
ATOM   5607  O OE2 . GLU B 1 338 ? 13.936  -34.362 10.796  1.00 37.46  ? 338 GLU B OE2 1 
ATOM   5608  N N   . ILE B 1 339 ? 8.878   -33.442 10.144  1.00 20.51  ? 339 ILE B N   1 
ATOM   5609  C CA  . ILE B 1 339 ? 8.533   -34.368 9.076   1.00 21.96  ? 339 ILE B CA  1 
ATOM   5610  C C   . ILE B 1 339 ? 9.688   -34.409 8.096   1.00 27.55  ? 339 ILE B C   1 
ATOM   5611  O O   . ILE B 1 339 ? 10.472  -33.462 7.961   1.00 27.93  ? 339 ILE B O   1 
ATOM   5612  C CB  . ILE B 1 339 ? 7.229   -34.016 8.325   1.00 22.74  ? 339 ILE B CB  1 
ATOM   5613  C CG1 . ILE B 1 339 ? 7.336   -32.635 7.653   1.00 23.55  ? 339 ILE B CG1 1 
ATOM   5614  C CG2 . ILE B 1 339 ? 6.032   -34.079 9.253   1.00 26.41  ? 339 ILE B CG2 1 
ATOM   5615  C CD1 . ILE B 1 339 ? 6.337   -32.454 6.508   1.00 19.70  ? 339 ILE B CD1 1 
ATOM   5616  N N   . ASN B 1 340 ? 9.785   -35.542 7.413   1.00 24.12  ? 340 ASN B N   1 
ATOM   5617  C CA  . ASN B 1 340 ? 10.729  -35.731 6.328   1.00 29.12  ? 340 ASN B CA  1 
ATOM   5618  C C   . ASN B 1 340 ? 9.957   -36.318 5.155   1.00 28.38  ? 340 ASN B C   1 
ATOM   5619  O O   . ASN B 1 340 ? 9.517   -37.474 5.212   1.00 21.94  ? 340 ASN B O   1 
ATOM   5620  C CB  . ASN B 1 340 ? 11.881  -36.637 6.759   1.00 30.57  ? 340 ASN B CB  1 
ATOM   5621  C CG  . ASN B 1 340 ? 12.848  -35.930 7.669   1.00 33.84  ? 340 ASN B CG  1 
ATOM   5622  O OD1 . ASN B 1 340 ? 13.679  -35.142 7.215   1.00 39.71  ? 340 ASN B OD1 1 
ATOM   5623  N ND2 . ASN B 1 340 ? 12.750  -36.201 8.960   1.00 35.43  ? 340 ASN B ND2 1 
ATOM   5624  N N   . ALA B 1 341 ? 9.777   -35.512 4.108   1.00 21.43  ? 341 ALA B N   1 
ATOM   5625  C CA  . ALA B 1 341 ? 9.111   -35.969 2.891   1.00 29.54  ? 341 ALA B CA  1 
ATOM   5626  C C   . ALA B 1 341 ? 10.178  -36.598 1.993   1.00 29.06  ? 341 ALA B C   1 
ATOM   5627  O O   . ALA B 1 341 ? 10.707  -35.982 1.063   1.00 21.64  ? 341 ALA B O   1 
ATOM   5628  C CB  . ALA B 1 341 ? 8.375   -34.820 2.213   1.00 24.56  ? 341 ALA B CB  1 
ATOM   5629  N N   . ARG B 1 342 ? 10.504  -37.850 2.312   1.00 27.37  ? 342 ARG B N   1 
ATOM   5630  C CA  . ARG B 1 342 ? 11.458  -38.698 1.603   1.00 29.30  ? 342 ARG B CA  1 
ATOM   5631  C C   . ARG B 1 342 ? 11.443  -40.032 2.331   1.00 24.68  ? 342 ARG B C   1 
ATOM   5632  O O   . ARG B 1 342 ? 10.842  -40.149 3.405   1.00 23.51  ? 342 ARG B O   1 
ATOM   5633  C CB  . ARG B 1 342 ? 12.874  -38.121 1.576   1.00 29.21  ? 342 ARG B CB  1 
ATOM   5634  C CG  . ARG B 1 342 ? 13.426  -37.789 2.953   1.00 28.87  ? 342 ARG B CG  1 
ATOM   5635  C CD  . ARG B 1 342 ? 14.872  -37.321 2.803   1.00 39.83  ? 342 ARG B CD  1 
ATOM   5636  N NE  . ARG B 1 342 ? 15.285  -36.381 3.837   1.00 39.96  ? 342 ARG B NE  1 
ATOM   5637  C CZ  . ARG B 1 342 ? 15.953  -36.731 4.926   1.00 42.68  ? 342 ARG B CZ  1 
ATOM   5638  N NH1 . ARG B 1 342 ? 16.268  -37.995 5.162   1.00 44.21  ? 342 ARG B NH1 1 
ATOM   5639  N NH2 . ARG B 1 342 ? 16.311  -35.791 5.799   1.00 48.54  ? 342 ARG B NH2 1 
ATOM   5640  N N   . TRP B 1 343 ? 12.108  -41.036 1.741   1.00 25.33  ? 343 TRP B N   1 
ATOM   5641  C CA  . TRP B 1 343 ? 12.234  -42.327 2.413   1.00 20.50  ? 343 TRP B CA  1 
ATOM   5642  C C   . TRP B 1 343 ? 12.818  -42.110 3.790   1.00 24.33  ? 343 TRP B C   1 
ATOM   5643  O O   . TRP B 1 343 ? 13.775  -41.352 3.952   1.00 27.28  ? 343 TRP B O   1 
ATOM   5644  C CB  . TRP B 1 343 ? 13.151  -43.288 1.660   1.00 23.14  ? 343 TRP B CB  1 
ATOM   5645  C CG  . TRP B 1 343 ? 12.818  -43.603 0.257   1.00 24.99  ? 343 TRP B CG  1 
ATOM   5646  C CD1 . TRP B 1 343 ? 11.602  -43.494 -0.354  1.00 25.72  ? 343 TRP B CD1 1 
ATOM   5647  C CD2 . TRP B 1 343 ? 13.716  -44.116 -0.720  1.00 28.78  ? 343 TRP B CD2 1 
ATOM   5648  N NE1 . TRP B 1 343 ? 11.691  -43.891 -1.651  1.00 28.76  ? 343 TRP B NE1 1 
ATOM   5649  C CE2 . TRP B 1 343 ? 12.981  -44.284 -1.909  1.00 31.04  ? 343 TRP B CE2 1 
ATOM   5650  C CE3 . TRP B 1 343 ? 15.081  -44.450 -0.709  1.00 28.93  ? 343 TRP B CE3 1 
ATOM   5651  C CZ2 . TRP B 1 343 ? 13.560  -44.767 -3.084  1.00 25.60  ? 343 TRP B CZ2 1 
ATOM   5652  C CZ3 . TRP B 1 343 ? 15.656  -44.922 -1.876  1.00 29.70  ? 343 TRP B CZ3 1 
ATOM   5653  C CH2 . TRP B 1 343 ? 14.894  -45.079 -3.048  1.00 26.87  ? 343 TRP B CH2 1 
ATOM   5654  N N   . SER B 1 344 ? 12.234  -42.755 4.782   1.00 22.92  ? 344 SER B N   1 
ATOM   5655  C CA  . SER B 1 344 ? 12.900  -42.795 6.066   1.00 24.58  ? 344 SER B CA  1 
ATOM   5656  C C   . SER B 1 344 ? 14.022  -43.820 5.993   1.00 27.33  ? 344 SER B C   1 
ATOM   5657  O O   . SER B 1 344 ? 14.081  -44.650 5.079   1.00 29.05  ? 344 SER B O   1 
ATOM   5658  C CB  . SER B 1 344 ? 11.912  -43.161 7.173   1.00 26.67  ? 344 SER B CB  1 
ATOM   5659  O OG  . SER B 1 344 ? 11.640  -44.565 7.146   1.00 22.63  ? 344 SER B OG  1 
ATOM   5660  N N   . GLY B 1 345 ? 14.923  -43.765 6.971   1.00 33.62  ? 345 GLY B N   1 
ATOM   5661  C CA  . GLY B 1 345 ? 16.017  -44.724 6.999   1.00 25.28  ? 345 GLY B CA  1 
ATOM   5662  C C   . GLY B 1 345 ? 15.533  -46.149 7.138   1.00 25.16  ? 345 GLY B C   1 
ATOM   5663  O O   . GLY B 1 345 ? 16.151  -47.067 6.599   1.00 26.69  ? 345 GLY B O   1 
ATOM   5664  N N   . GLY B 1 346 ? 14.396  -46.345 7.808   1.00 26.20  ? 346 GLY B N   1 
ATOM   5665  C CA  . GLY B 1 346 ? 13.815  -47.643 8.074   1.00 23.60  ? 346 GLY B CA  1 
ATOM   5666  C C   . GLY B 1 346 ? 12.724  -48.108 7.129   1.00 28.79  ? 346 GLY B C   1 
ATOM   5667  O O   . GLY B 1 346 ? 12.090  -49.138 7.406   1.00 24.20  ? 346 GLY B O   1 
ATOM   5668  N N   . LEU B 1 347 ? 12.476  -47.388 6.024   1.00 27.49  ? 347 LEU B N   1 
ATOM   5669  C CA  . LEU B 1 347 ? 11.517  -47.878 5.032   1.00 25.15  ? 347 LEU B CA  1 
ATOM   5670  C C   . LEU B 1 347 ? 12.011  -49.163 4.378   1.00 26.41  ? 347 LEU B C   1 
ATOM   5671  O O   . LEU B 1 347 ? 11.202  -50.027 4.012   1.00 27.68  ? 347 LEU B O   1 
ATOM   5672  C CB  . LEU B 1 347 ? 11.248  -46.820 3.952   1.00 22.12  ? 347 LEU B CB  1 
ATOM   5673  C CG  . LEU B 1 347 ? 10.364  -47.316 2.781   1.00 23.40  ? 347 LEU B CG  1 
ATOM   5674  C CD1 . LEU B 1 347 ? 8.966   -47.763 3.235   1.00 14.76  ? 347 LEU B CD1 1 
ATOM   5675  C CD2 . LEU B 1 347 ? 10.263  -46.316 1.619   1.00 21.99  ? 347 LEU B CD2 1 
ATOM   5676  N N   . ILE B 1 348 ? 13.329  -49.306 4.213   1.00 22.89  ? 348 ILE B N   1 
ATOM   5677  C CA  . ILE B 1 348 ? 13.835  -50.545 3.642   1.00 26.68  ? 348 ILE B CA  1 
ATOM   5678  C C   . ILE B 1 348 ? 13.594  -51.695 4.614   1.00 22.25  ? 348 ILE B C   1 
ATOM   5679  O O   . ILE B 1 348 ? 13.291  -52.821 4.196   1.00 22.31  ? 348 ILE B O   1 
ATOM   5680  C CB  . ILE B 1 348 ? 15.322  -50.376 3.248   1.00 24.45  ? 348 ILE B CB  1 
ATOM   5681  C CG1 . ILE B 1 348 ? 15.828  -51.593 2.461   1.00 27.35  ? 348 ILE B CG1 1 
ATOM   5682  C CG2 . ILE B 1 348 ? 16.181  -50.164 4.456   1.00 24.84  ? 348 ILE B CG2 1 
ATOM   5683  C CD1 . ILE B 1 348 ? 15.344  -51.613 1.017   1.00 32.65  ? 348 ILE B CD1 1 
ATOM   5684  N N   . TYR B 1 349 ? 13.667  -51.423 5.917   1.00 20.00  ? 349 TYR B N   1 
ATOM   5685  C CA  . TYR B 1 349 ? 13.400  -52.456 6.910   1.00 23.54  ? 349 TYR B CA  1 
ATOM   5686  C C   . TYR B 1 349 ? 11.964  -52.944 6.830   1.00 24.92  ? 349 TYR B C   1 
ATOM   5687  O O   . TYR B 1 349 ? 11.704  -54.153 6.852   1.00 23.97  ? 349 TYR B O   1 
ATOM   5688  C CB  . TYR B 1 349 ? 13.670  -51.933 8.315   1.00 24.71  ? 349 TYR B CB  1 
ATOM   5689  C CG  . TYR B 1 349 ? 15.049  -51.402 8.585   1.00 27.24  ? 349 TYR B CG  1 
ATOM   5690  C CD1 . TYR B 1 349 ? 16.167  -51.895 7.925   1.00 24.80  ? 349 TYR B CD1 1 
ATOM   5691  C CD2 . TYR B 1 349 ? 15.227  -50.400 9.528   1.00 30.20  ? 349 TYR B CD2 1 
ATOM   5692  C CE1 . TYR B 1 349 ? 17.433  -51.372 8.208   1.00 29.75  ? 349 TYR B CE1 1 
ATOM   5693  C CE2 . TYR B 1 349 ? 16.459  -49.884 9.806   1.00 30.93  ? 349 TYR B CE2 1 
ATOM   5694  C CZ  . TYR B 1 349 ? 17.561  -50.366 9.153   1.00 29.85  ? 349 TYR B CZ  1 
ATOM   5695  O OH  . TYR B 1 349 ? 18.785  -49.826 9.489   1.00 32.53  ? 349 TYR B OH  1 
ATOM   5696  N N   . HIS B 1 350 ? 11.010  -52.011 6.789   1.00 25.60  ? 350 HIS B N   1 
ATOM   5697  C CA  . HIS B 1 350 ? 9.601   -52.375 6.663   1.00 21.15  ? 350 HIS B CA  1 
ATOM   5698  C C   . HIS B 1 350 ? 9.353   -53.127 5.368   1.00 25.02  ? 350 HIS B C   1 
ATOM   5699  O O   . HIS B 1 350 ? 8.567   -54.080 5.334   1.00 28.08  ? 350 HIS B O   1 
ATOM   5700  C CB  . HIS B 1 350 ? 8.730   -51.115 6.727   1.00 24.11  ? 350 HIS B CB  1 
ATOM   5701  C CG  . HIS B 1 350 ? 7.317   -51.325 6.280   1.00 26.20  ? 350 HIS B CG  1 
ATOM   5702  N ND1 . HIS B 1 350 ? 6.353   -51.885 7.096   1.00 21.05  ? 350 HIS B ND1 1 
ATOM   5703  C CD2 . HIS B 1 350 ? 6.702   -51.049 5.103   1.00 25.78  ? 350 HIS B CD2 1 
ATOM   5704  C CE1 . HIS B 1 350 ? 5.208   -51.947 6.437   1.00 23.26  ? 350 HIS B CE1 1 
ATOM   5705  N NE2 . HIS B 1 350 ? 5.394   -51.450 5.227   1.00 24.17  ? 350 HIS B NE2 1 
ATOM   5706  N N   . THR B 1 351 ? 10.009  -52.704 4.285   1.00 25.60  ? 351 THR B N   1 
ATOM   5707  C CA  . THR B 1 351 ? 9.836   -53.381 3.010   1.00 26.12  ? 351 THR B CA  1 
ATOM   5708  C C   . THR B 1 351 ? 10.295  -54.833 3.105   1.00 25.13  ? 351 THR B C   1 
ATOM   5709  O O   . THR B 1 351 ? 9.570   -55.747 2.711   1.00 29.49  ? 351 THR B O   1 
ATOM   5710  C CB  . THR B 1 351 ? 10.612  -52.649 1.918   1.00 25.50  ? 351 THR B CB  1 
ATOM   5711  O OG1 . THR B 1 351 ? 10.097  -51.319 1.753   1.00 28.12  ? 351 THR B OG1 1 
ATOM   5712  C CG2 . THR B 1 351 ? 10.513  -53.426 0.589   1.00 24.85  ? 351 THR B CG2 1 
ATOM   5713  N N   . VAL B 1 352 ? 11.504  -55.058 3.627   1.00 23.99  ? 352 VAL B N   1 
ATOM   5714  C CA  . VAL B 1 352 ? 12.011  -56.418 3.815   1.00 17.73  ? 352 VAL B CA  1 
ATOM   5715  C C   . VAL B 1 352 ? 11.087  -57.211 4.728   1.00 21.68  ? 352 VAL B C   1 
ATOM   5716  O O   . VAL B 1 352 ? 10.806  -58.387 4.478   1.00 28.91  ? 352 VAL B O   1 
ATOM   5717  C CB  . VAL B 1 352 ? 13.452  -56.398 4.371   1.00 18.05  ? 352 VAL B CB  1 
ATOM   5718  C CG1 . VAL B 1 352 ? 13.976  -57.830 4.562   1.00 21.66  ? 352 VAL B CG1 1 
ATOM   5719  C CG2 . VAL B 1 352 ? 14.381  -55.628 3.442   1.00 21.33  ? 352 VAL B CG2 1 
ATOM   5720  N N   . ALA B 1 353 ? 10.622  -56.594 5.811   1.00 24.99  ? 353 ALA B N   1 
ATOM   5721  C CA  . ALA B 1 353 ? 9.749   -57.289 6.749   1.00 26.40  ? 353 ALA B CA  1 
ATOM   5722  C C   . ALA B 1 353 ? 8.532   -57.848 6.031   1.00 24.07  ? 353 ALA B C   1 
ATOM   5723  O O   . ALA B 1 353 ? 8.181   -59.019 6.200   1.00 26.37  ? 353 ALA B O   1 
ATOM   5724  C CB  . ALA B 1 353 ? 9.329   -56.347 7.879   1.00 21.56  ? 353 ALA B CB  1 
ATOM   5725  N N   . GLU B 1 354 ? 7.907   -57.033 5.182   1.00 25.54  ? 354 GLU B N   1 
ATOM   5726  C CA  . GLU B 1 354 ? 6.701   -57.477 4.485   1.00 24.36  ? 354 GLU B CA  1 
ATOM   5727  C C   . GLU B 1 354 ? 7.000   -58.632 3.543   1.00 24.39  ? 354 GLU B C   1 
ATOM   5728  O O   . GLU B 1 354 ? 6.245   -59.610 3.488   1.00 21.67  ? 354 GLU B O   1 
ATOM   5729  C CB  . GLU B 1 354 ? 6.073   -56.310 3.719   1.00 25.28  ? 354 GLU B CB  1 
ATOM   5730  C CG  . GLU B 1 354 ? 5.454   -55.249 4.624   1.00 26.52  ? 354 GLU B CG  1 
ATOM   5731  C CD  . GLU B 1 354 ? 4.319   -54.491 3.941   1.00 32.40  ? 354 GLU B CD  1 
ATOM   5732  O OE1 . GLU B 1 354 ? 4.510   -54.016 2.800   1.00 29.33  ? 354 GLU B OE1 1 
ATOM   5733  O OE2 . GLU B 1 354 ? 3.235   -54.367 4.561   1.00 37.47  ? 354 GLU B OE2 1 
ATOM   5734  N N   . ARG B 1 355 ? 8.099   -58.534 2.783   1.00 24.70  ? 355 ARG B N   1 
ATOM   5735  C CA  . ARG B 1 355 ? 8.367   -59.548 1.770   1.00 29.73  ? 355 ARG B CA  1 
ATOM   5736  C C   . ARG B 1 355 ? 8.795   -60.865 2.397   1.00 25.18  ? 355 ARG B C   1 
ATOM   5737  O O   . ARG B 1 355 ? 8.442   -61.939 1.900   1.00 31.04  ? 355 ARG B O   1 
ATOM   5738  C CB  . ARG B 1 355 ? 9.419   -59.046 0.793   1.00 29.41  ? 355 ARG B CB  1 
ATOM   5739  C CG  . ARG B 1 355 ? 8.940   -57.849 0.014   1.00 26.63  ? 355 ARG B CG  1 
ATOM   5740  C CD  . ARG B 1 355 ? 10.062  -57.318 -0.804  1.00 30.71  ? 355 ARG B CD  1 
ATOM   5741  N NE  . ARG B 1 355 ? 10.294  -58.176 -1.953  1.00 30.36  ? 355 ARG B NE  1 
ATOM   5742  C CZ  . ARG B 1 355 ? 11.054  -57.844 -2.985  1.00 35.75  ? 355 ARG B CZ  1 
ATOM   5743  N NH1 . ARG B 1 355 ? 11.727  -56.700 -3.008  1.00 32.24  ? 355 ARG B NH1 1 
ATOM   5744  N NH2 . ARG B 1 355 ? 11.142  -58.680 -4.020  1.00 35.58  ? 355 ARG B NH2 1 
ATOM   5745  N N   . LEU B 1 356 ? 9.541   -60.804 3.489   1.00 25.14  ? 356 LEU B N   1 
ATOM   5746  C CA  . LEU B 1 356 ? 9.988   -62.022 4.146   1.00 25.48  ? 356 LEU B CA  1 
ATOM   5747  C C   . LEU B 1 356 ? 8.907   -62.595 5.048   1.00 30.58  ? 356 LEU B C   1 
ATOM   5748  O O   . LEU B 1 356 ? 8.701   -63.815 5.083   1.00 29.26  ? 356 LEU B O   1 
ATOM   5749  C CB  . LEU B 1 356 ? 11.248  -61.732 4.966   1.00 31.38  ? 356 LEU B CB  1 
ATOM   5750  C CG  . LEU B 1 356 ? 12.505  -61.411 4.159   1.00 29.06  ? 356 LEU B CG  1 
ATOM   5751  C CD1 . LEU B 1 356 ? 13.748  -61.552 5.031   1.00 26.91  ? 356 LEU B CD1 1 
ATOM   5752  C CD2 . LEU B 1 356 ? 12.576  -62.319 2.945   1.00 27.36  ? 356 LEU B CD2 1 
ATOM   5753  N N   . LEU B 1 357 ? 8.214   -61.730 5.792   1.00 29.48  ? 357 LEU B N   1 
ATOM   5754  C CA  . LEU B 1 357 ? 7.353   -62.191 6.868   1.00 26.42  ? 357 LEU B CA  1 
ATOM   5755  C C   . LEU B 1 357 ? 5.865   -62.042 6.587   1.00 25.48  ? 357 LEU B C   1 
ATOM   5756  O O   . LEU B 1 357 ? 5.073   -62.673 7.284   1.00 30.47  ? 357 LEU B O   1 
ATOM   5757  C CB  . LEU B 1 357 ? 7.693   -61.457 8.173   1.00 28.20  ? 357 LEU B CB  1 
ATOM   5758  C CG  . LEU B 1 357 ? 9.128   -61.640 8.670   1.00 31.84  ? 357 LEU B CG  1 
ATOM   5759  C CD1 . LEU B 1 357 ? 9.317   -61.019 10.050  1.00 27.67  ? 357 LEU B CD1 1 
ATOM   5760  C CD2 . LEU B 1 357 ? 9.500   -63.116 8.683   1.00 35.40  ? 357 LEU B CD2 1 
ATOM   5761  N N   . GLY B 1 358 ? 5.466   -61.256 5.588   1.00 23.51  ? 358 GLY B N   1 
ATOM   5762  C CA  . GLY B 1 358 ? 4.064   -61.057 5.276   1.00 31.13  ? 358 GLY B CA  1 
ATOM   5763  C C   . GLY B 1 358 ? 3.542   -59.726 5.797   1.00 27.40  ? 358 GLY B C   1 
ATOM   5764  O O   . GLY B 1 358 ? 4.191   -59.027 6.574   1.00 24.12  ? 358 GLY B O   1 
ATOM   5765  N N   . HIS B 1 359 ? 2.293   -59.422 5.423   1.00 26.73  ? 359 HIS B N   1 
ATOM   5766  C CA  . HIS B 1 359 ? 1.817   -58.038 5.406   1.00 34.62  ? 359 HIS B CA  1 
ATOM   5767  C C   . HIS B 1 359 ? 1.476   -57.447 6.786   1.00 36.69  ? 359 HIS B C   1 
ATOM   5768  O O   . HIS B 1 359 ? 1.656   -56.235 6.986   1.00 44.70  ? 359 HIS B O   1 
ATOM   5769  C CB  . HIS B 1 359 ? 0.627   -57.941 4.466   1.00 33.76  ? 359 HIS B CB  1 
ATOM   5770  C CG  . HIS B 1 359 ? 0.989   -57.406 3.121   1.00 38.22  ? 359 HIS B CG  1 
ATOM   5771  N ND1 . HIS B 1 359 ? 1.210   -56.067 2.888   1.00 47.45  ? 359 HIS B ND1 1 
ATOM   5772  C CD2 . HIS B 1 359 ? 1.231   -58.037 1.947   1.00 41.62  ? 359 HIS B CD2 1 
ATOM   5773  C CE1 . HIS B 1 359 ? 1.536   -55.891 1.620   1.00 46.82  ? 359 HIS B CE1 1 
ATOM   5774  N NE2 . HIS B 1 359 ? 1.562   -57.072 1.029   1.00 49.13  ? 359 HIS B NE2 1 
ATOM   5775  N N   . ASP B 1 360 ? 0.993   -58.224 7.750   1.00 30.99  ? 360 ASP B N   1 
ATOM   5776  C CA  . ASP B 1 360 ? 0.759   -57.683 9.094   1.00 30.13  ? 360 ASP B CA  1 
ATOM   5777  C C   . ASP B 1 360 ? 1.813   -58.186 10.091  1.00 33.20  ? 360 ASP B C   1 
ATOM   5778  O O   . ASP B 1 360 ? 1.505   -58.502 11.248  1.00 31.86  ? 360 ASP B O   1 
ATOM   5779  C CB  . ASP B 1 360 ? -0.655  -58.021 9.574   1.00 29.64  ? 360 ASP B CB  1 
ATOM   5780  C CG  . ASP B 1 360 ? -1.741  -57.298 8.777   1.00 34.14  ? 360 ASP B CG  1 
ATOM   5781  O OD1 . ASP B 1 360 ? -1.736  -56.043 8.726   1.00 34.55  ? 360 ASP B OD1 1 
ATOM   5782  O OD2 . ASP B 1 360 ? -2.582  -57.990 8.160   1.00 36.41  ? 360 ASP B OD2 1 
ATOM   5783  N N   . TYR B 1 361 ? 3.073   -58.258 9.638   1.00 24.62  ? 361 TYR B N   1 
ATOM   5784  C CA  . TYR B 1 361 ? 4.142   -58.860 10.431  1.00 25.54  ? 361 TYR B CA  1 
ATOM   5785  C C   . TYR B 1 361 ? 4.227   -58.243 11.818  1.00 26.36  ? 361 TYR B C   1 
ATOM   5786  O O   . TYR B 1 361 ? 4.467   -58.951 12.803  1.00 27.43  ? 361 TYR B O   1 
ATOM   5787  C CB  . TYR B 1 361 ? 5.491   -58.711 9.707   1.00 19.97  ? 361 TYR B CB  1 
ATOM   5788  C CG  . TYR B 1 361 ? 5.936   -57.264 9.574   1.00 24.36  ? 361 TYR B CG  1 
ATOM   5789  C CD1 . TYR B 1 361 ? 6.627   -56.623 10.605  1.00 25.14  ? 361 TYR B CD1 1 
ATOM   5790  C CD2 . TYR B 1 361 ? 5.662   -56.534 8.426   1.00 23.28  ? 361 TYR B CD2 1 
ATOM   5791  C CE1 . TYR B 1 361 ? 7.000   -55.301 10.506  1.00 27.18  ? 361 TYR B CE1 1 
ATOM   5792  C CE2 . TYR B 1 361 ? 6.061   -55.195 8.313   1.00 25.33  ? 361 TYR B CE2 1 
ATOM   5793  C CZ  . TYR B 1 361 ? 6.714   -54.591 9.352   1.00 22.79  ? 361 TYR B CZ  1 
ATOM   5794  O OH  . TYR B 1 361 ? 7.102   -53.286 9.253   1.00 26.14  ? 361 TYR B OH  1 
ATOM   5795  N N   . ALA B 1 362 ? 4.001   -56.926 11.917  1.00 27.01  ? 362 ALA B N   1 
ATOM   5796  C CA  . ALA B 1 362 ? 4.232   -56.189 13.161  1.00 27.92  ? 362 ALA B CA  1 
ATOM   5797  C C   . ALA B 1 362 ? 3.380   -56.698 14.313  1.00 27.77  ? 362 ALA B C   1 
ATOM   5798  O O   . ALA B 1 362 ? 3.696   -56.423 15.474  1.00 34.26  ? 362 ALA B O   1 
ATOM   5799  C CB  . ALA B 1 362 ? 3.979   -54.686 12.962  1.00 29.90  ? 362 ALA B CB  1 
ATOM   5800  N N   . ARG B 1 363 ? 2.331   -57.454 14.033  1.00 29.94  ? 363 ARG B N   1 
ATOM   5801  C CA  . ARG B 1 363 ? 1.501   -57.960 15.115  1.00 32.30  ? 363 ARG B CA  1 
ATOM   5802  C C   . ARG B 1 363 ? 2.092   -59.186 15.791  1.00 35.49  ? 363 ARG B C   1 
ATOM   5803  O O   . ARG B 1 363 ? 1.801   -59.420 16.968  1.00 36.50  ? 363 ARG B O   1 
ATOM   5804  C CB  . ARG B 1 363 ? 0.104   -58.242 14.576  1.00 30.81  ? 363 ARG B CB  1 
ATOM   5805  C CG  . ARG B 1 363 ? -0.456  -56.990 13.908  1.00 33.16  ? 363 ARG B CG  1 
ATOM   5806  C CD  . ARG B 1 363 ? -1.808  -57.206 13.295  1.00 36.63  ? 363 ARG B CD  1 
ATOM   5807  N NE  . ARG B 1 363 ? -2.452  -55.926 13.026  1.00 30.72  ? 363 ARG B NE  1 
ATOM   5808  C CZ  . ARG B 1 363 ? -3.569  -55.788 12.318  1.00 37.81  ? 363 ARG B CZ  1 
ATOM   5809  N NH1 . ARG B 1 363 ? -4.189  -56.841 11.787  1.00 30.41  ? 363 ARG B NH1 1 
ATOM   5810  N NH2 . ARG B 1 363 ? -4.081  -54.566 12.143  1.00 25.29  ? 363 ARG B NH2 1 
ATOM   5811  N N   . ASN B 1 364 ? 2.953   -59.940 15.103  1.00 31.26  ? 364 ASN B N   1 
ATOM   5812  C CA  . ASN B 1 364 ? 3.495   -61.172 15.659  1.00 33.95  ? 364 ASN B CA  1 
ATOM   5813  C C   . ASN B 1 364 ? 5.006   -61.283 15.489  1.00 36.74  ? 364 ASN B C   1 
ATOM   5814  O O   . ASN B 1 364 ? 5.559   -62.376 15.676  1.00 36.67  ? 364 ASN B O   1 
ATOM   5815  C CB  . ASN B 1 364 ? 2.801   -62.383 15.012  1.00 36.99  ? 364 ASN B CB  1 
ATOM   5816  C CG  . ASN B 1 364 ? 1.277   -62.302 15.111  1.00 44.47  ? 364 ASN B CG  1 
ATOM   5817  O OD1 . ASN B 1 364 ? 0.709   -62.378 16.204  1.00 43.81  ? 364 ASN B OD1 1 
ATOM   5818  N ND2 . ASN B 1 364 ? 0.612   -62.138 13.966  1.00 42.62  ? 364 ASN B ND2 1 
ATOM   5819  N N   . ASN B 1 365 ? 5.682   -60.195 15.119  1.00 33.85  ? 365 ASN B N   1 
ATOM   5820  C CA  . ASN B 1 365 ? 7.112   -60.218 14.850  1.00 32.41  ? 365 ASN B CA  1 
ATOM   5821  C C   . ASN B 1 365 ? 7.734   -58.899 15.281  1.00 33.60  ? 365 ASN B C   1 
ATOM   5822  O O   . ASN B 1 365 ? 7.076   -57.854 15.290  1.00 32.38  ? 365 ASN B O   1 
ATOM   5823  C CB  . ASN B 1 365 ? 7.407   -60.444 13.369  1.00 31.63  ? 365 ASN B CB  1 
ATOM   5824  C CG  . ASN B 1 365 ? 6.778   -61.707 12.832  1.00 35.90  ? 365 ASN B CG  1 
ATOM   5825  O OD1 . ASN B 1 365 ? 7.354   -62.794 12.930  1.00 35.08  ? 365 ASN B OD1 1 
ATOM   5826  N ND2 . ASN B 1 365 ? 5.592   -61.574 12.257  1.00 29.01  ? 365 ASN B ND2 1 
ATOM   5827  N N   . PHE B 1 366 ? 9.012   -58.954 15.601  1.00 25.60  ? 366 PHE B N   1 
ATOM   5828  C CA  . PHE B 1 366 ? 9.806   -57.760 15.821  1.00 30.58  ? 366 PHE B CA  1 
ATOM   5829  C C   . PHE B 1 366 ? 10.971  -57.742 14.844  1.00 30.57  ? 366 PHE B C   1 
ATOM   5830  O O   . PHE B 1 366 ? 11.367  -58.778 14.295  1.00 23.29  ? 366 PHE B O   1 
ATOM   5831  C CB  . PHE B 1 366 ? 10.321  -57.705 17.261  1.00 31.15  ? 366 PHE B CB  1 
ATOM   5832  C CG  . PHE B 1 366 ? 9.248   -57.923 18.293  1.00 33.17  ? 366 PHE B CG  1 
ATOM   5833  C CD1 . PHE B 1 366 ? 8.911   -59.215 18.707  1.00 33.85  ? 366 PHE B CD1 1 
ATOM   5834  C CD2 . PHE B 1 366 ? 8.584   -56.847 18.856  1.00 30.09  ? 366 PHE B CD2 1 
ATOM   5835  C CE1 . PHE B 1 366 ? 7.929   -59.427 19.649  1.00 29.93  ? 366 PHE B CE1 1 
ATOM   5836  C CE2 . PHE B 1 366 ? 7.590   -57.047 19.811  1.00 34.76  ? 366 PHE B CE2 1 
ATOM   5837  C CZ  . PHE B 1 366 ? 7.259   -58.347 20.207  1.00 29.99  ? 366 PHE B CZ  1 
ATOM   5838  N N   . PHE B 1 367 ? 11.508  -56.551 14.606  1.00 24.45  ? 367 PHE B N   1 
ATOM   5839  C CA  . PHE B 1 367 ? 12.756  -56.458 13.883  1.00 27.08  ? 367 PHE B CA  1 
ATOM   5840  C C   . PHE B 1 367 ? 13.593  -55.344 14.478  1.00 32.71  ? 367 PHE B C   1 
ATOM   5841  O O   . PHE B 1 367 ? 13.103  -54.464 15.191  1.00 34.55  ? 367 PHE B O   1 
ATOM   5842  C CB  . PHE B 1 367 ? 12.570  -56.314 12.349  1.00 27.18  ? 367 PHE B CB  1 
ATOM   5843  C CG  . PHE B 1 367 ? 12.193  -54.931 11.841  1.00 29.15  ? 367 PHE B CG  1 
ATOM   5844  C CD1 . PHE B 1 367 ? 13.047  -53.841 11.950  1.00 28.54  ? 367 PHE B CD1 1 
ATOM   5845  C CD2 . PHE B 1 367 ? 11.009  -54.764 11.134  1.00 31.98  ? 367 PHE B CD2 1 
ATOM   5846  C CE1 . PHE B 1 367 ? 12.698  -52.602 11.421  1.00 32.68  ? 367 PHE B CE1 1 
ATOM   5847  C CE2 . PHE B 1 367 ? 10.648  -53.531 10.599  1.00 30.06  ? 367 PHE B CE2 1 
ATOM   5848  C CZ  . PHE B 1 367 ? 11.481  -52.449 10.740  1.00 25.56  ? 367 PHE B CZ  1 
ATOM   5849  N N   . SER B 1 368 ? 14.880  -55.411 14.185  1.00 29.61  ? 368 SER B N   1 
ATOM   5850  C CA  . SER B 1 368 ? 15.827  -54.487 14.769  1.00 29.56  ? 368 SER B CA  1 
ATOM   5851  C C   . SER B 1 368 ? 17.043  -54.514 13.870  1.00 32.37  ? 368 SER B C   1 
ATOM   5852  O O   . SER B 1 368 ? 17.397  -55.572 13.340  1.00 28.37  ? 368 SER B O   1 
ATOM   5853  C CB  . SER B 1 368 ? 16.155  -54.895 16.207  1.00 28.95  ? 368 SER B CB  1 
ATOM   5854  O OG  . SER B 1 368 ? 17.123  -54.060 16.791  1.00 30.42  ? 368 SER B OG  1 
ATOM   5855  N N   . SER B 1 369 ? 17.634  -53.349 13.649  1.00 32.79  ? 369 SER B N   1 
ATOM   5856  C CA  . SER B 1 369 ? 18.774  -53.233 12.757  1.00 32.37  ? 369 SER B CA  1 
ATOM   5857  C C   . SER B 1 369 ? 20.015  -52.926 13.572  1.00 35.04  ? 369 SER B C   1 
ATOM   5858  O O   . SER B 1 369 ? 19.932  -52.455 14.706  1.00 35.00  ? 369 SER B O   1 
ATOM   5859  C CB  . SER B 1 369 ? 18.578  -52.132 11.725  1.00 30.84  ? 369 SER B CB  1 
ATOM   5860  O OG  . SER B 1 369 ? 18.614  -50.867 12.360  1.00 31.33  ? 369 SER B OG  1 
ATOM   5861  N N   . ILE B 1 370 ? 21.169  -53.210 12.978  1.00 35.98  ? 370 ILE B N   1 
ATOM   5862  C CA  . ILE B 1 370 ? 22.465  -52.926 13.584  1.00 36.01  ? 370 ILE B CA  1 
ATOM   5863  C C   . ILE B 1 370 ? 23.312  -52.231 12.535  1.00 34.43  ? 370 ILE B C   1 
ATOM   5864  O O   . ILE B 1 370 ? 23.531  -52.780 11.445  1.00 34.56  ? 370 ILE B O   1 
ATOM   5865  C CB  . ILE B 1 370 ? 23.167  -54.193 14.093  1.00 33.80  ? 370 ILE B CB  1 
ATOM   5866  C CG1 . ILE B 1 370 ? 22.191  -55.052 14.910  1.00 33.08  ? 370 ILE B CG1 1 
ATOM   5867  C CG2 . ILE B 1 370 ? 24.395  -53.811 14.917  1.00 29.42  ? 370 ILE B CG2 1 
ATOM   5868  C CD1 . ILE B 1 370 ? 22.788  -56.343 15.412  1.00 28.78  ? 370 ILE B CD1 1 
ATOM   5869  N N   . LEU B 1 371 ? 23.790  -51.031 12.858  1.00 32.39  ? 371 LEU B N   1 
ATOM   5870  C CA  . LEU B 1 371 ? 24.490  -50.212 11.878  1.00 36.90  ? 371 LEU B CA  1 
ATOM   5871  C C   . LEU B 1 371 ? 26.006  -50.273 11.982  1.00 34.09  ? 371 LEU B C   1 
ATOM   5872  O O   . LEU B 1 371 ? 26.681  -49.858 11.038  1.00 27.19  ? 371 LEU B O   1 
ATOM   5873  C CB  . LEU B 1 371 ? 24.043  -48.752 11.997  1.00 33.03  ? 371 LEU B CB  1 
ATOM   5874  C CG  . LEU B 1 371 ? 22.551  -48.558 12.222  1.00 41.82  ? 371 LEU B CG  1 
ATOM   5875  C CD1 . LEU B 1 371 ? 22.294  -47.191 12.810  1.00 44.83  ? 371 LEU B CD1 1 
ATOM   5876  C CD2 . LEU B 1 371 ? 21.845  -48.765 10.860  1.00 40.60  ? 371 LEU B CD2 1 
ATOM   5877  N N   . ASN B 1 372 ? 26.551  -50.803 13.083  1.00 36.69  ? 372 ASN B N   1 
ATOM   5878  C CA  . ASN B 1 372 ? 27.963  -50.645 13.417  1.00 41.14  ? 372 ASN B CA  1 
ATOM   5879  C C   . ASN B 1 372 ? 28.689  -51.979 13.570  1.00 40.62  ? 372 ASN B C   1 
ATOM   5880  O O   . ASN B 1 372 ? 29.633  -52.079 14.360  1.00 42.42  ? 372 ASN B O   1 
ATOM   5881  C CB  . ASN B 1 372 ? 28.107  -49.834 14.703  1.00 42.24  ? 372 ASN B CB  1 
ATOM   5882  C CG  . ASN B 1 372 ? 27.235  -50.371 15.811  1.00 41.19  ? 372 ASN B CG  1 
ATOM   5883  O OD1 . ASN B 1 372 ? 27.034  -51.582 15.920  1.00 44.87  ? 372 ASN B OD1 1 
ATOM   5884  N ND2 . ASN B 1 372 ? 26.702  -49.480 16.638  1.00 50.74  ? 372 ASN B ND2 1 
ATOM   5885  N N   . VAL B 1 373 ? 28.247  -53.018 12.850  1.00 38.85  ? 373 VAL B N   1 
ATOM   5886  C CA  . VAL B 1 373 ? 28.975  -54.285 12.840  1.00 34.16  ? 373 VAL B CA  1 
ATOM   5887  C C   . VAL B 1 373 ? 30.295  -54.100 12.099  1.00 32.77  ? 373 VAL B C   1 
ATOM   5888  O O   . VAL B 1 373 ? 30.400  -53.292 11.165  1.00 30.90  ? 373 VAL B O   1 
ATOM   5889  C CB  . VAL B 1 373 ? 28.109  -55.389 12.202  1.00 38.02  ? 373 VAL B CB  1 
ATOM   5890  C CG1 . VAL B 1 373 ? 28.964  -56.438 11.445  1.00 31.74  ? 373 VAL B CG1 1 
ATOM   5891  C CG2 . VAL B 1 373 ? 27.247  -56.053 13.263  1.00 37.07  ? 373 VAL B CG2 1 
ATOM   5892  N N   . VAL B 1 374 ? 31.320  -54.838 12.524  1.00 35.12  ? 374 VAL B N   1 
ATOM   5893  C CA  . VAL B 1 374 ? 32.656  -54.661 11.951  1.00 34.53  ? 374 VAL B CA  1 
ATOM   5894  C C   . VAL B 1 374 ? 32.612  -54.971 10.458  1.00 33.49  ? 374 VAL B C   1 
ATOM   5895  O O   . VAL B 1 374 ? 32.192  -56.067 10.058  1.00 31.57  ? 374 VAL B O   1 
ATOM   5896  C CB  . VAL B 1 374 ? 33.714  -55.516 12.669  1.00 31.04  ? 374 VAL B CB  1 
ATOM   5897  C CG1 . VAL B 1 374 ? 35.052  -55.354 11.972  1.00 31.30  ? 374 VAL B CG1 1 
ATOM   5898  C CG2 . VAL B 1 374 ? 33.835  -55.100 14.127  1.00 33.40  ? 374 VAL B CG2 1 
ATOM   5899  N N   . PRO B 1 375 ? 32.991  -54.020 9.608   1.00 33.02  ? 375 PRO B N   1 
ATOM   5900  C CA  . PRO B 1 375 ? 32.861  -54.224 8.163   1.00 27.66  ? 375 PRO B CA  1 
ATOM   5901  C C   . PRO B 1 375 ? 33.636  -55.447 7.707   1.00 30.98  ? 375 PRO B C   1 
ATOM   5902  O O   . PRO B 1 375 ? 34.743  -55.719 8.179   1.00 32.64  ? 375 PRO B O   1 
ATOM   5903  C CB  . PRO B 1 375 ? 33.439  -52.932 7.571   1.00 25.46  ? 375 PRO B CB  1 
ATOM   5904  C CG  . PRO B 1 375 ? 33.177  -51.906 8.628   1.00 34.37  ? 375 PRO B CG  1 
ATOM   5905  C CD  . PRO B 1 375 ? 33.368  -52.635 9.944   1.00 31.20  ? 375 PRO B CD  1 
ATOM   5906  N N   . ALA B 1 376 ? 33.027  -56.199 6.797   1.00 32.52  ? 376 ALA B N   1 
ATOM   5907  C CA  . ALA B 1 376 ? 33.642  -57.395 6.235   1.00 29.92  ? 376 ALA B CA  1 
ATOM   5908  C C   . ALA B 1 376 ? 32.938  -57.711 4.929   1.00 30.57  ? 376 ALA B C   1 
ATOM   5909  O O   . ALA B 1 376 ? 31.842  -57.210 4.663   1.00 33.98  ? 376 ALA B O   1 
ATOM   5910  C CB  . ALA B 1 376 ? 33.565  -58.581 7.202   1.00 31.45  ? 376 ALA B CB  1 
ATOM   5911  N N   . GLY B 1 377 ? 33.598  -58.513 4.097   1.00 30.90  ? 377 GLY B N   1 
ATOM   5912  C CA  . GLY B 1 377 ? 32.983  -58.946 2.859   1.00 28.11  ? 377 GLY B CA  1 
ATOM   5913  C C   . GLY B 1 377 ? 31.712  -59.736 3.105   1.00 26.59  ? 377 GLY B C   1 
ATOM   5914  O O   . GLY B 1 377 ? 31.496  -60.309 4.182   1.00 31.14  ? 377 GLY B O   1 
ATOM   5915  N N   . LEU B 1 378 ? 30.850  -59.747 2.084   1.00 29.16  ? 378 LEU B N   1 
ATOM   5916  C CA  . LEU B 1 378 ? 29.549  -60.410 2.197   1.00 30.12  ? 378 LEU B CA  1 
ATOM   5917  C C   . LEU B 1 378 ? 29.711  -61.870 2.609   1.00 28.19  ? 378 LEU B C   1 
ATOM   5918  O O   . LEU B 1 378 ? 29.065  -62.338 3.558   1.00 25.83  ? 378 LEU B O   1 
ATOM   5919  C CB  . LEU B 1 378 ? 28.793  -60.308 0.870   1.00 29.33  ? 378 LEU B CB  1 
ATOM   5920  C CG  . LEU B 1 378 ? 27.368  -60.883 0.817   1.00 30.12  ? 378 LEU B CG  1 
ATOM   5921  C CD1 . LEU B 1 378 ? 26.562  -60.460 2.016   1.00 21.07  ? 378 LEU B CD1 1 
ATOM   5922  C CD2 . LEU B 1 378 ? 26.656  -60.460 -0.447  1.00 29.61  ? 378 LEU B CD2 1 
ATOM   5923  N N   . ALA B 1 379 ? 30.609  -62.586 1.923   1.00 29.83  ? 379 ALA B N   1 
ATOM   5924  C CA  . ALA B 1 379 ? 30.902  -63.974 2.270   1.00 32.37  ? 379 ALA B CA  1 
ATOM   5925  C C   . ALA B 1 379 ? 31.254  -64.119 3.743   1.00 32.15  ? 379 ALA B C   1 
ATOM   5926  O O   . ALA B 1 379 ? 30.806  -65.065 4.403   1.00 34.32  ? 379 ALA B O   1 
ATOM   5927  C CB  . ALA B 1 379 ? 32.038  -64.507 1.402   1.00 30.65  ? 379 ALA B CB  1 
ATOM   5928  N N   . ASP B 1 380 ? 32.046  -63.188 4.281   1.00 33.30  ? 380 ASP B N   1 
ATOM   5929  C CA  . ASP B 1 380 ? 32.485  -63.314 5.668   1.00 34.31  ? 380 ASP B CA  1 
ATOM   5930  C C   . ASP B 1 380 ? 31.383  -62.929 6.653   1.00 33.54  ? 380 ASP B C   1 
ATOM   5931  O O   . ASP B 1 380 ? 31.318  -63.481 7.765   1.00 28.15  ? 380 ASP B O   1 
ATOM   5932  C CB  . ASP B 1 380 ? 33.724  -62.454 5.893   1.00 33.15  ? 380 ASP B CB  1 
ATOM   5933  C CG  . ASP B 1 380 ? 34.931  -62.953 5.108   1.00 33.98  ? 380 ASP B CG  1 
ATOM   5934  O OD1 . ASP B 1 380 ? 35.103  -64.178 4.972   1.00 31.55  ? 380 ASP B OD1 1 
ATOM   5935  O OD2 . ASP B 1 380 ? 35.700  -62.110 4.604   1.00 41.83  ? 380 ASP B OD2 1 
ATOM   5936  N N   . LEU B 1 381 ? 30.523  -61.985 6.255   1.00 29.73  ? 381 LEU B N   1 
ATOM   5937  C CA  . LEU B 1 381 ? 29.381  -61.609 7.078   1.00 30.89  ? 381 LEU B CA  1 
ATOM   5938  C C   . LEU B 1 381 ? 28.371  -62.747 7.156   1.00 26.39  ? 381 LEU B C   1 
ATOM   5939  O O   . LEU B 1 381 ? 27.865  -63.069 8.237   1.00 28.12  ? 381 LEU B O   1 
ATOM   5940  C CB  . LEU B 1 381 ? 28.725  -60.350 6.511   1.00 25.15  ? 381 LEU B CB  1 
ATOM   5941  C CG  . LEU B 1 381 ? 29.479  -59.046 6.686   1.00 31.00  ? 381 LEU B CG  1 
ATOM   5942  C CD1 . LEU B 1 381 ? 28.544  -57.907 6.335   1.00 36.76  ? 381 LEU B CD1 1 
ATOM   5943  C CD2 . LEU B 1 381 ? 30.004  -58.904 8.104   1.00 26.68  ? 381 LEU B CD2 1 
ATOM   5944  N N   . LEU B 1 382 ? 28.046  -63.352 6.013   1.00 26.71  ? 382 LEU B N   1 
ATOM   5945  C CA  . LEU B 1 382 ? 27.136  -64.490 6.035   1.00 26.69  ? 382 LEU B CA  1 
ATOM   5946  C C   . LEU B 1 382 ? 27.706  -65.602 6.901   1.00 29.37  ? 382 LEU B C   1 
ATOM   5947  O O   . LEU B 1 382 ? 27.000  -66.176 7.741   1.00 25.03  ? 382 LEU B O   1 
ATOM   5948  C CB  . LEU B 1 382 ? 26.874  -64.972 4.613   1.00 22.43  ? 382 LEU B CB  1 
ATOM   5949  C CG  . LEU B 1 382 ? 26.115  -63.950 3.773   1.00 25.68  ? 382 LEU B CG  1 
ATOM   5950  C CD1 . LEU B 1 382 ? 26.036  -64.376 2.305   1.00 26.80  ? 382 LEU B CD1 1 
ATOM   5951  C CD2 . LEU B 1 382 ? 24.720  -63.695 4.343   1.00 26.36  ? 382 LEU B CD2 1 
ATOM   5952  N N   . ARG B 1 383 ? 29.012  -65.856 6.767   1.00 29.75  ? 383 ARG B N   1 
ATOM   5953  C CA  . ARG B 1 383 ? 29.640  -66.927 7.531   1.00 26.54  ? 383 ARG B CA  1 
ATOM   5954  C C   . ARG B 1 383 ? 29.510  -66.685 9.034   1.00 31.59  ? 383 ARG B C   1 
ATOM   5955  O O   . ARG B 1 383 ? 29.189  -67.617 9.788   1.00 23.90  ? 383 ARG B O   1 
ATOM   5956  C CB  . ARG B 1 383 ? 31.103  -67.063 7.104   1.00 27.55  ? 383 ARG B CB  1 
ATOM   5957  C CG  . ARG B 1 383 ? 31.832  -68.227 7.734   1.00 31.85  ? 383 ARG B CG  1 
ATOM   5958  C CD  . ARG B 1 383 ? 31.612  -69.534 6.971   1.00 29.58  ? 383 ARG B CD  1 
ATOM   5959  N NE  . ARG B 1 383 ? 30.299  -70.133 7.223   1.00 27.07  ? 383 ARG B NE  1 
ATOM   5960  C CZ  . ARG B 1 383 ? 30.015  -70.952 8.228   1.00 25.48  ? 383 ARG B CZ  1 
ATOM   5961  N NH1 . ARG B 1 383 ? 30.879  -71.186 9.195   1.00 29.20  ? 383 ARG B NH1 1 
ATOM   5962  N NH2 . ARG B 1 383 ? 28.834  -71.560 8.258   1.00 29.62  ? 383 ARG B NH2 1 
ATOM   5963  N N   . SER B 1 384 ? 29.734  -65.433 9.491   1.00 24.59  ? 384 SER B N   1 
ATOM   5964  C CA  . SER B 1 384 ? 29.556  -65.127 10.910  1.00 24.02  ? 384 SER B CA  1 
ATOM   5965  C C   . SER B 1 384 ? 28.101  -65.264 11.328  1.00 27.09  ? 384 SER B C   1 
ATOM   5966  O O   . SER B 1 384 ? 27.825  -65.653 12.468  1.00 26.17  ? 384 SER B O   1 
ATOM   5967  C CB  . SER B 1 384 ? 30.045  -63.716 11.253  1.00 29.53  ? 384 SER B CB  1 
ATOM   5968  O OG  . SER B 1 384 ? 31.210  -63.347 10.537  1.00 29.23  ? 384 SER B OG  1 
ATOM   5969  N N   . LEU B 1 385 ? 27.156  -64.980 10.422  1.00 27.57  ? 385 LEU B N   1 
ATOM   5970  C CA  . LEU B 1 385 ? 25.751  -65.208 10.746  1.00 28.47  ? 385 LEU B CA  1 
ATOM   5971  C C   . LEU B 1 385 ? 25.475  -66.700 10.920  1.00 25.70  ? 385 LEU B C   1 
ATOM   5972  O O   . LEU B 1 385 ? 24.822  -67.113 11.885  1.00 27.74  ? 385 LEU B O   1 
ATOM   5973  C CB  . LEU B 1 385 ? 24.844  -64.591 9.673   1.00 23.84  ? 385 LEU B CB  1 
ATOM   5974  C CG  . LEU B 1 385 ? 24.810  -63.052 9.657   1.00 27.14  ? 385 LEU B CG  1 
ATOM   5975  C CD1 . LEU B 1 385 ? 23.841  -62.546 8.596   1.00 25.30  ? 385 LEU B CD1 1 
ATOM   5976  C CD2 . LEU B 1 385 ? 24.462  -62.479 11.040  1.00 21.56  ? 385 LEU B CD2 1 
ATOM   5977  N N   . GLU B 1 386 ? 26.000  -67.533 10.018  1.00 29.56  ? 386 GLU B N   1 
ATOM   5978  C CA  . GLU B 1 386 ? 25.858  -68.978 10.201  1.00 28.90  ? 386 GLU B CA  1 
ATOM   5979  C C   . GLU B 1 386 ? 26.552  -69.440 11.476  1.00 25.92  ? 386 GLU B C   1 
ATOM   5980  O O   . GLU B 1 386 ? 25.997  -70.250 12.228  1.00 31.83  ? 386 GLU B O   1 
ATOM   5981  C CB  . GLU B 1 386 ? 26.406  -69.726 8.991   1.00 25.73  ? 386 GLU B CB  1 
ATOM   5982  C CG  . GLU B 1 386 ? 25.717  -69.374 7.698   1.00 25.93  ? 386 GLU B CG  1 
ATOM   5983  C CD  . GLU B 1 386 ? 26.123  -70.254 6.527   1.00 29.93  ? 386 GLU B CD  1 
ATOM   5984  O OE1 . GLU B 1 386 ? 26.522  -71.433 6.730   1.00 30.44  ? 386 GLU B OE1 1 
ATOM   5985  O OE2 . GLU B 1 386 ? 26.047  -69.745 5.393   1.00 26.82  ? 386 GLU B OE2 1 
ATOM   5986  N N   . ARG B 1 387 ? 27.751  -68.909 11.758  1.00 27.13  ? 387 ARG B N   1 
ATOM   5987  C CA  . ARG B 1 387 ? 28.462  -69.282 12.983  1.00 29.35  ? 387 ARG B CA  1 
ATOM   5988  C C   . ARG B 1 387 ? 27.668  -68.888 14.228  1.00 32.86  ? 387 ARG B C   1 
ATOM   5989  O O   . ARG B 1 387 ? 27.618  -69.642 15.207  1.00 35.93  ? 387 ARG B O   1 
ATOM   5990  C CB  . ARG B 1 387 ? 29.854  -68.648 13.004  1.00 30.76  ? 387 ARG B CB  1 
ATOM   5991  C CG  . ARG B 1 387 ? 30.805  -69.155 14.122  1.00 27.95  ? 387 ARG B CG  1 
ATOM   5992  C CD  . ARG B 1 387 ? 32.075  -68.295 14.168  1.00 33.58  ? 387 ARG B CD  1 
ATOM   5993  N NE  . ARG B 1 387 ? 32.575  -68.063 12.818  1.00 36.09  ? 387 ARG B NE  1 
ATOM   5994  C CZ  . ARG B 1 387 ? 32.744  -66.868 12.264  1.00 40.56  ? 387 ARG B CZ  1 
ATOM   5995  N NH1 . ARG B 1 387 ? 32.560  -65.750 12.953  1.00 34.15  ? 387 ARG B NH1 1 
ATOM   5996  N NH2 . ARG B 1 387 ? 33.107  -66.791 10.985  1.00 34.91  ? 387 ARG B NH2 1 
ATOM   5997  N N   . ALA B 1 388 ? 27.026  -67.721 14.207  1.00 29.58  ? 388 ALA B N   1 
ATOM   5998  C CA  . ALA B 1 388 ? 26.118  -67.333 15.287  1.00 35.33  ? 388 ALA B CA  1 
ATOM   5999  C C   . ALA B 1 388 ? 24.888  -68.227 15.370  1.00 33.04  ? 388 ALA B C   1 
ATOM   6000  O O   . ALA B 1 388 ? 24.171  -68.184 16.379  1.00 37.37  ? 388 ALA B O   1 
ATOM   6001  C CB  . ALA B 1 388 ? 25.678  -65.871 15.106  1.00 25.93  ? 388 ALA B CB  1 
ATOM   6002  N N   . GLY B 1 389 ? 24.617  -69.017 14.335  1.00 32.80  ? 389 GLY B N   1 
ATOM   6003  C CA  . GLY B 1 389 ? 23.375  -69.760 14.274  1.00 30.64  ? 389 GLY B CA  1 
ATOM   6004  C C   . GLY B 1 389 ? 22.145  -68.928 13.986  1.00 31.73  ? 389 GLY B C   1 
ATOM   6005  O O   . GLY B 1 389 ? 21.038  -69.377 14.280  1.00 30.52  ? 389 GLY B O   1 
ATOM   6006  N N   . VAL B 1 390 ? 22.294  -67.727 13.410  1.00 32.63  ? 390 VAL B N   1 
ATOM   6007  C CA  . VAL B 1 390 ? 21.139  -66.847 13.207  1.00 29.77  ? 390 VAL B CA  1 
ATOM   6008  C C   . VAL B 1 390 ? 21.107  -66.231 11.804  1.00 32.73  ? 390 VAL B C   1 
ATOM   6009  O O   . VAL B 1 390 ? 20.525  -65.160 11.599  1.00 24.15  ? 390 VAL B O   1 
ATOM   6010  C CB  . VAL B 1 390 ? 21.098  -65.737 14.278  1.00 33.68  ? 390 VAL B CB  1 
ATOM   6011  C CG1 . VAL B 1 390 ? 21.085  -66.337 15.707  1.00 30.59  ? 390 VAL B CG1 1 
ATOM   6012  C CG2 . VAL B 1 390 ? 22.257  -64.768 14.102  1.00 25.10  ? 390 VAL B CG2 1 
ATOM   6013  N N   . ARG B 1 391 ? 21.697  -66.898 10.816  1.00 28.19  ? 391 ARG B N   1 
ATOM   6014  C CA  . ARG B 1 391 ? 21.473  -66.460 9.448   1.00 25.18  ? 391 ARG B CA  1 
ATOM   6015  C C   . ARG B 1 391 ? 20.003  -66.646 9.107   1.00 30.70  ? 391 ARG B C   1 
ATOM   6016  O O   . ARG B 1 391 ? 19.401  -67.661 9.467   1.00 26.61  ? 391 ARG B O   1 
ATOM   6017  C CB  . ARG B 1 391 ? 22.345  -67.236 8.471   1.00 25.15  ? 391 ARG B CB  1 
ATOM   6018  C CG  . ARG B 1 391 ? 21.899  -67.067 7.048   1.00 24.61  ? 391 ARG B CG  1 
ATOM   6019  C CD  . ARG B 1 391 ? 23.009  -67.165 6.049   1.00 25.11  ? 391 ARG B CD  1 
ATOM   6020  N NE  . ARG B 1 391 ? 22.489  -67.106 4.687   1.00 21.27  ? 391 ARG B NE  1 
ATOM   6021  C CZ  . ARG B 1 391 ? 23.221  -67.355 3.613   1.00 23.86  ? 391 ARG B CZ  1 
ATOM   6022  N NH1 . ARG B 1 391 ? 24.471  -67.763 3.711   1.00 23.42  ? 391 ARG B NH1 1 
ATOM   6023  N NH2 . ARG B 1 391 ? 22.685  -67.202 2.411   1.00 23.23  ? 391 ARG B NH2 1 
ATOM   6024  N N   . TYR B 1 392 ? 19.422  -65.657 8.412   1.00 28.48  ? 392 TYR B N   1 
ATOM   6025  C CA  . TYR B 1 392 ? 17.983  -65.648 8.201   1.00 29.16  ? 392 TYR B CA  1 
ATOM   6026  C C   . TYR B 1 392 ? 17.496  -66.954 7.599   1.00 27.08  ? 392 TYR B C   1 
ATOM   6027  O O   . TYR B 1 392 ? 17.945  -67.363 6.523   1.00 25.73  ? 392 TYR B O   1 
ATOM   6028  C CB  . TYR B 1 392 ? 17.546  -64.512 7.287   1.00 28.62  ? 392 TYR B CB  1 
ATOM   6029  C CG  . TYR B 1 392 ? 16.049  -64.596 7.075   1.00 30.20  ? 392 TYR B CG  1 
ATOM   6030  C CD1 . TYR B 1 392 ? 15.171  -64.179 8.074   1.00 31.31  ? 392 TYR B CD1 1 
ATOM   6031  C CD2 . TYR B 1 392 ? 15.516  -65.140 5.917   1.00 28.07  ? 392 TYR B CD2 1 
ATOM   6032  C CE1 . TYR B 1 392 ? 13.807  -64.264 7.903   1.00 36.30  ? 392 TYR B CE1 1 
ATOM   6033  C CE2 . TYR B 1 392 ? 14.152  -65.233 5.739   1.00 28.60  ? 392 TYR B CE2 1 
ATOM   6034  C CZ  . TYR B 1 392 ? 13.304  -64.796 6.737   1.00 31.01  ? 392 TYR B CZ  1 
ATOM   6035  O OH  . TYR B 1 392 ? 11.944  -64.872 6.579   1.00 41.62  ? 392 TYR B OH  1 
ATOM   6036  N N   . ASP B 1 393 ? 16.510  -67.550 8.271   1.00 31.80  ? 393 ASP B N   1 
ATOM   6037  C CA  . ASP B 1 393 ? 15.994  -68.891 7.995   1.00 33.86  ? 393 ASP B CA  1 
ATOM   6038  C C   . ASP B 1 393 ? 14.524  -68.748 7.601   1.00 28.60  ? 393 ASP B C   1 
ATOM   6039  O O   . ASP B 1 393 ? 13.667  -68.525 8.462   1.00 29.28  ? 393 ASP B O   1 
ATOM   6040  C CB  . ASP B 1 393 ? 16.185  -69.790 9.227   1.00 28.38  ? 393 ASP B CB  1 
ATOM   6041  C CG  . ASP B 1 393 ? 15.637  -71.213 9.032   1.00 37.68  ? 393 ASP B CG  1 
ATOM   6042  O OD1 . ASP B 1 393 ? 15.288  -71.594 7.890   1.00 31.63  ? 393 ASP B OD1 1 
ATOM   6043  O OD2 . ASP B 1 393 ? 15.593  -71.965 10.031  1.00 37.26  ? 393 ASP B OD2 1 
ATOM   6044  N N   . LYS B 1 394 ? 14.237  -68.909 6.304   1.00 25.71  ? 394 LYS B N   1 
ATOM   6045  C CA  . LYS B 1 394 ? 12.880  -68.711 5.786   1.00 33.74  ? 394 LYS B CA  1 
ATOM   6046  C C   . LYS B 1 394 ? 11.876  -69.763 6.275   1.00 35.76  ? 394 LYS B C   1 
ATOM   6047  O O   . LYS B 1 394 ? 10.664  -69.530 6.176   1.00 32.78  ? 394 LYS B O   1 
ATOM   6048  C CB  . LYS B 1 394 ? 12.899  -68.680 4.254   1.00 30.43  ? 394 LYS B CB  1 
ATOM   6049  C CG  . LYS B 1 394 ? 13.835  -69.683 3.599   1.00 31.92  ? 394 LYS B CG  1 
ATOM   6050  C CD  . LYS B 1 394 ? 14.592  -69.023 2.437   1.00 43.29  ? 394 LYS B CD  1 
ATOM   6051  C CE  . LYS B 1 394 ? 15.817  -68.227 2.934   1.00 43.89  ? 394 LYS B CE  1 
ATOM   6052  N NZ  . LYS B 1 394 ? 16.348  -67.287 1.893   1.00 38.42  ? 394 LYS B NZ  1 
ATOM   6053  N N   . ASP B 1 395 ? 12.344  -70.900 6.807   1.00 28.85  ? 395 ASP B N   1 
ATOM   6054  C CA  . ASP B 1 395 ? 11.437  -71.866 7.429   1.00 32.33  ? 395 ASP B CA  1 
ATOM   6055  C C   . ASP B 1 395 ? 10.898  -71.366 8.768   1.00 37.65  ? 395 ASP B C   1 
ATOM   6056  O O   . ASP B 1 395 ? 9.772   -71.708 9.145   1.00 37.65  ? 395 ASP B O   1 
ATOM   6057  C CB  . ASP B 1 395 ? 12.138  -73.213 7.645   1.00 37.93  ? 395 ASP B CB  1 
ATOM   6058  C CG  . ASP B 1 395 ? 12.429  -73.953 6.337   1.00 45.53  ? 395 ASP B CG  1 
ATOM   6059  O OD1 . ASP B 1 395 ? 11.792  -73.632 5.308   1.00 46.94  ? 395 ASP B OD1 1 
ATOM   6060  O OD2 . ASP B 1 395 ? 13.290  -74.862 6.344   1.00 37.11  ? 395 ASP B OD2 1 
ATOM   6061  N N   . SER B 1 396 ? 11.686  -70.588 9.510   1.00 34.49  ? 396 SER B N   1 
ATOM   6062  C CA  . SER B 1 396 ? 11.276  -70.071 10.806  1.00 29.67  ? 396 SER B CA  1 
ATOM   6063  C C   . SER B 1 396 ? 10.830  -68.617 10.770  1.00 35.22  ? 396 SER B C   1 
ATOM   6064  O O   . SER B 1 396 ? 10.218  -68.156 11.739  1.00 34.52  ? 396 SER B O   1 
ATOM   6065  C CB  . SER B 1 396 ? 12.430  -70.164 11.805  1.00 31.75  ? 396 SER B CB  1 
ATOM   6066  O OG  . SER B 1 396 ? 13.616  -69.649 11.217  1.00 35.98  ? 396 SER B OG  1 
ATOM   6067  N N   . GLY B 1 397 ? 11.161  -67.884 9.708   1.00 31.84  ? 397 GLY B N   1 
ATOM   6068  C CA  . GLY B 1 397 ? 11.023  -66.440 9.679   1.00 36.83  ? 397 GLY B CA  1 
ATOM   6069  C C   . GLY B 1 397 ? 11.978  -65.681 10.576  1.00 41.53  ? 397 GLY B C   1 
ATOM   6070  O O   . GLY B 1 397 ? 11.753  -64.495 10.840  1.00 40.91  ? 397 GLY B O   1 
ATOM   6071  N N   . GLU B 1 398 ? 13.043  -66.312 11.068  1.00 38.13  ? 398 GLU B N   1 
ATOM   6072  C CA  . GLU B 1 398 ? 13.860  -65.695 12.100  1.00 33.35  ? 398 GLU B CA  1 
ATOM   6073  C C   . GLU B 1 398 ? 15.303  -65.633 11.638  1.00 34.70  ? 398 GLU B C   1 
ATOM   6074  O O   . GLU B 1 398 ? 15.771  -66.510 10.909  1.00 37.15  ? 398 GLU B O   1 
ATOM   6075  C CB  . GLU B 1 398 ? 13.740  -66.458 13.415  1.00 33.34  ? 398 GLU B CB  1 
ATOM   6076  C CG  . GLU B 1 398 ? 12.297  -66.558 13.889  1.00 38.26  ? 398 GLU B CG  1 
ATOM   6077  C CD  . GLU B 1 398 ? 12.171  -66.369 15.384  1.00 39.14  ? 398 GLU B CD  1 
ATOM   6078  O OE1 . GLU B 1 398 ? 13.184  -65.967 15.991  1.00 42.36  ? 398 GLU B OE1 1 
ATOM   6079  O OE2 . GLU B 1 398 ? 11.062  -66.554 15.933  1.00 38.47  ? 398 GLU B OE2 1 
ATOM   6080  N N   . GLY B 1 399 ? 16.000  -64.585 12.052  1.00 27.81  ? 399 GLY B N   1 
ATOM   6081  C CA  . GLY B 1 399 ? 17.383  -64.448 11.661  1.00 32.10  ? 399 GLY B CA  1 
ATOM   6082  C C   . GLY B 1 399 ? 17.663  -63.118 11.014  1.00 26.03  ? 399 GLY B C   1 
ATOM   6083  O O   . GLY B 1 399 ? 16.846  -62.193 11.047  1.00 28.43  ? 399 GLY B O   1 
ATOM   6084  N N   . ALA B 1 400 ? 18.826  -63.031 10.384  1.00 24.80  ? 400 ALA B N   1 
ATOM   6085  C CA  . ALA B 1 400 ? 19.413  -61.760 10.004  1.00 24.56  ? 400 ALA B CA  1 
ATOM   6086  C C   . ALA B 1 400 ? 19.783  -61.764 8.535   1.00 28.27  ? 400 ALA B C   1 
ATOM   6087  O O   . ALA B 1 400 ? 20.277  -62.771 8.012   1.00 26.09  ? 400 ALA B O   1 
ATOM   6088  C CB  . ALA B 1 400 ? 20.651  -61.475 10.843  1.00 29.51  ? 400 ALA B CB  1 
ATOM   6089  N N   . VAL B 1 401 ? 19.544  -60.630 7.874   1.00 27.13  ? 401 VAL B N   1 
ATOM   6090  C CA  . VAL B 1 401 ? 19.964  -60.424 6.497   1.00 21.29  ? 401 VAL B CA  1 
ATOM   6091  C C   . VAL B 1 401 ? 20.894  -59.235 6.502   1.00 27.59  ? 401 VAL B C   1 
ATOM   6092  O O   . VAL B 1 401 ? 20.872  -58.405 7.415   1.00 26.41  ? 401 VAL B O   1 
ATOM   6093  C CB  . VAL B 1 401 ? 18.803  -60.149 5.526   1.00 28.34  ? 401 VAL B CB  1 
ATOM   6094  C CG1 . VAL B 1 401 ? 18.036  -61.422 5.216   1.00 30.73  ? 401 VAL B CG1 1 
ATOM   6095  C CG2 . VAL B 1 401 ? 17.913  -59.022 6.060   1.00 28.79  ? 401 VAL B CG2 1 
ATOM   6096  N N   . VAL B 1 402 ? 21.674  -59.127 5.434   1.00 29.80  ? 402 VAL B N   1 
ATOM   6097  C CA  . VAL B 1 402 ? 22.691  -58.101 5.297   1.00 25.03  ? 402 VAL B CA  1 
ATOM   6098  C C   . VAL B 1 402 ? 22.136  -56.998 4.413   1.00 27.66  ? 402 VAL B C   1 
ATOM   6099  O O   . VAL B 1 402 ? 21.638  -57.260 3.312   1.00 29.52  ? 402 VAL B O   1 
ATOM   6100  C CB  . VAL B 1 402 ? 23.992  -58.695 4.733   1.00 23.06  ? 402 VAL B CB  1 
ATOM   6101  C CG1 . VAL B 1 402 ? 24.998  -57.620 4.479   1.00 26.53  ? 402 VAL B CG1 1 
ATOM   6102  C CG2 . VAL B 1 402 ? 24.543  -59.690 5.733   1.00 23.85  ? 402 VAL B CG2 1 
ATOM   6103  N N   . LEU B 1 403 ? 22.193  -55.763 4.905   1.00 25.06  ? 403 LEU B N   1 
ATOM   6104  C CA  . LEU B 1 403 ? 21.775  -54.627 4.105   1.00 31.74  ? 403 LEU B CA  1 
ATOM   6105  C C   . LEU B 1 403 ? 22.952  -53.900 3.490   1.00 34.19  ? 403 LEU B C   1 
ATOM   6106  O O   . LEU B 1 403 ? 22.814  -53.328 2.403   1.00 32.48  ? 403 LEU B O   1 
ATOM   6107  C CB  . LEU B 1 403 ? 20.954  -53.647 4.943   1.00 28.38  ? 403 LEU B CB  1 
ATOM   6108  C CG  . LEU B 1 403 ? 19.561  -54.097 5.405   1.00 35.15  ? 403 LEU B CG  1 
ATOM   6109  C CD1 . LEU B 1 403 ? 18.621  -52.902 5.416   1.00 26.80  ? 403 LEU B CD1 1 
ATOM   6110  C CD2 . LEU B 1 403 ? 18.996  -55.228 4.573   1.00 28.96  ? 403 LEU B CD2 1 
ATOM   6111  N N   . GLY B 1 404 ? 24.103  -53.932 4.156   1.00 29.40  ? 404 GLY B N   1 
ATOM   6112  C CA  . GLY B 1 404 ? 25.317  -53.349 3.625   1.00 28.39  ? 404 GLY B CA  1 
ATOM   6113  C C   . GLY B 1 404 ? 26.516  -53.966 4.306   1.00 30.23  ? 404 GLY B C   1 
ATOM   6114  O O   . GLY B 1 404 ? 26.480  -54.218 5.512   1.00 29.99  ? 404 GLY B O   1 
ATOM   6115  N N   . CYS B 1 405 ? 27.574  -54.227 3.545   1.00 27.45  ? 405 CYS B N   1 
ATOM   6116  C CA  . CYS B 1 405 ? 28.782  -54.824 4.097   1.00 33.91  ? 405 CYS B CA  1 
ATOM   6117  C C   . CYS B 1 405 ? 29.704  -53.795 4.699   1.00 36.27  ? 405 CYS B C   1 
ATOM   6118  O O   . CYS B 1 405 ? 30.498  -54.126 5.590   1.00 33.56  ? 405 CYS B O   1 
ATOM   6119  C CB  . CYS B 1 405 ? 29.550  -55.591 3.016   1.00 31.41  ? 405 CYS B CB  1 
ATOM   6120  S SG  . CYS B 1 405 ? 28.529  -56.776 2.125   1.00 35.94  ? 405 CYS B SG  1 
ATOM   6121  N N   . ASN B 1 406 ? 29.620  -52.552 4.229   1.00 42.06  ? 406 ASN B N   1 
ATOM   6122  C CA  . ASN B 1 406 ? 30.578  -51.535 4.636   1.00 40.62  ? 406 ASN B CA  1 
ATOM   6123  C C   . ASN B 1 406 ? 30.014  -50.164 4.314   1.00 39.72  ? 406 ASN B C   1 
ATOM   6124  O O   . ASN B 1 406 ? 30.413  -49.541 3.325   1.00 39.06  ? 406 ASN B O   1 
ATOM   6125  C CB  . ASN B 1 406 ? 31.918  -51.767 3.934   1.00 34.26  ? 406 ASN B CB  1 
ATOM   6126  C CG  . ASN B 1 406 ? 32.863  -50.612 4.095   1.00 33.39  ? 406 ASN B CG  1 
ATOM   6127  O OD1 . ASN B 1 406 ? 33.063  -50.108 5.196   1.00 35.56  ? 406 ASN B OD1 1 
ATOM   6128  N ND2 . ASN B 1 406 ? 33.453  -50.183 2.996   1.00 38.59  ? 406 ASN B ND2 1 
ATOM   6129  N N   . SER B 1 407 ? 29.067  -49.698 5.126   1.00 40.87  ? 407 SER B N   1 
ATOM   6130  C CA  . SER B 1 407 ? 28.265  -48.536 4.775   1.00 43.10  ? 407 SER B CA  1 
ATOM   6131  C C   . SER B 1 407 ? 28.524  -47.360 5.711   1.00 44.35  ? 407 SER B C   1 
ATOM   6132  O O   . SER B 1 407 ? 28.906  -47.526 6.878   1.00 33.42  ? 407 SER B O   1 
ATOM   6133  C CB  . SER B 1 407 ? 26.768  -48.863 4.809   1.00 41.07  ? 407 SER B CB  1 
ATOM   6134  O OG  . SER B 1 407 ? 26.244  -48.638 6.105   1.00 38.35  ? 407 SER B OG  1 
ATOM   6135  N N   . ASP B 1 408 ? 28.268  -46.167 5.171   1.00 42.67  ? 408 ASP B N   1 
ATOM   6136  C CA  . ASP B 1 408 ? 28.283  -44.919 5.924   1.00 43.88  ? 408 ASP B CA  1 
ATOM   6137  C C   . ASP B 1 408 ? 26.890  -44.626 6.489   1.00 48.11  ? 408 ASP B C   1 
ATOM   6138  O O   . ASP B 1 408 ? 26.190  -43.715 6.043   1.00 51.85  ? 408 ASP B O   1 
ATOM   6139  C CB  . ASP B 1 408 ? 28.766  -43.791 5.024   1.00 45.37  ? 408 ASP B CB  1 
ATOM   6140  C CG  . ASP B 1 408 ? 30.263  -43.803 4.846   1.00 57.83  ? 408 ASP B CG  1 
ATOM   6141  O OD1 . ASP B 1 408 ? 30.939  -44.488 5.648   1.00 60.92  ? 408 ASP B OD1 1 
ATOM   6142  O OD2 . ASP B 1 408 ? 30.766  -43.136 3.912   1.00 66.90  ? 408 ASP B OD2 1 
ATOM   6143  N N   . LEU B 1 409 ? 26.487  -45.444 7.478   1.00 38.94  ? 409 LEU B N   1 
ATOM   6144  C CA  . LEU B 1 409 ? 25.288  -45.219 8.298   1.00 38.95  ? 409 LEU B CA  1 
ATOM   6145  C C   . LEU B 1 409 ? 25.626  -45.259 9.784   1.00 41.15  ? 409 LEU B C   1 
ATOM   6146  O O   . LEU B 1 409 ? 25.310  -44.327 10.535  1.00 30.93  ? 409 LEU B O   1 
ATOM   6147  C CB  . LEU B 1 409 ? 24.199  -46.261 8.027   1.00 42.10  ? 409 LEU B CB  1 
ATOM   6148  C CG  . LEU B 1 409 ? 22.873  -45.926 7.334   1.00 42.25  ? 409 LEU B CG  1 
ATOM   6149  C CD1 . LEU B 1 409 ? 23.104  -45.414 5.931   1.00 45.70  ? 409 LEU B CD1 1 
ATOM   6150  C CD2 . LEU B 1 409 ? 21.939  -47.169 7.316   1.00 38.41  ? 409 LEU B CD2 1 
ATOM   6151  N N   . GLY B 1 410 ? 26.239  -46.359 10.218  1.00 34.30  ? 410 GLY B N   1 
ATOM   6152  C CA  . GLY B 1 410 ? 26.708  -46.493 11.576  1.00 38.30  ? 410 GLY B CA  1 
ATOM   6153  C C   . GLY B 1 410 ? 27.781  -45.491 11.972  1.00 40.69  ? 410 GLY B C   1 
ATOM   6154  O O   . GLY B 1 410 ? 27.661  -44.799 12.988  1.00 40.22  ? 410 GLY B O   1 
ATOM   6155  N N   . PRO B 1 411 ? 28.876  -45.414 11.198  1.00 36.66  ? 411 PRO B N   1 
ATOM   6156  C CA  . PRO B 1 411 ? 29.188  -46.168 9.979   1.00 37.72  ? 411 PRO B CA  1 
ATOM   6157  C C   . PRO B 1 411 ? 29.433  -47.644 10.292  1.00 38.13  ? 411 PRO B C   1 
ATOM   6158  O O   . PRO B 1 411 ? 29.656  -47.998 11.460  1.00 32.67  ? 411 PRO B O   1 
ATOM   6159  C CB  . PRO B 1 411 ? 30.461  -45.499 9.483   1.00 44.69  ? 411 PRO B CB  1 
ATOM   6160  C CG  . PRO B 1 411 ? 31.167  -45.131 10.764  1.00 42.20  ? 411 PRO B CG  1 
ATOM   6161  C CD  . PRO B 1 411 ? 30.076  -44.748 11.740  1.00 39.69  ? 411 PRO B CD  1 
ATOM   6162  N N   . GLY B 1 412 ? 29.370  -48.493 9.280   1.00 36.14  ? 412 GLY B N   1 
ATOM   6163  C CA  . GLY B 1 412 ? 29.664  -49.896 9.481   1.00 29.57  ? 412 GLY B CA  1 
ATOM   6164  C C   . GLY B 1 412 ? 28.904  -50.765 8.501   1.00 32.97  ? 412 GLY B C   1 
ATOM   6165  O O   . GLY B 1 412 ? 28.449  -50.318 7.448   1.00 33.51  ? 412 GLY B O   1 
ATOM   6166  N N   . ALA B 1 413 ? 28.832  -52.039 8.839   1.00 31.06  ? 413 ALA B N   1 
ATOM   6167  C CA  . ALA B 1 413 ? 28.016  -52.956 8.075   1.00 35.70  ? 413 ALA B CA  1 
ATOM   6168  C C   . ALA B 1 413 ? 26.653  -52.989 8.744   1.00 28.23  ? 413 ALA B C   1 
ATOM   6169  O O   . ALA B 1 413 ? 26.560  -53.061 9.973   1.00 26.73  ? 413 ALA B O   1 
ATOM   6170  C CB  . ALA B 1 413 ? 28.648  -54.349 8.012   1.00 36.95  ? 413 ALA B CB  1 
ATOM   6171  N N   . GLU B 1 414 ? 25.609  -52.893 7.939   1.00 32.67  ? 414 GLU B N   1 
ATOM   6172  C CA  . GLU B 1 414 ? 24.247  -52.803 8.440   1.00 32.31  ? 414 GLU B CA  1 
ATOM   6173  C C   . GLU B 1 414 ? 23.576  -54.158 8.254   1.00 31.23  ? 414 GLU B C   1 
ATOM   6174  O O   . GLU B 1 414 ? 23.487  -54.667 7.130   1.00 30.95  ? 414 GLU B O   1 
ATOM   6175  C CB  . GLU B 1 414 ? 23.483  -51.686 7.726   1.00 30.65  ? 414 GLU B CB  1 
ATOM   6176  C CG  . GLU B 1 414 ? 22.036  -51.543 8.165   1.00 31.37  ? 414 GLU B CG  1 
ATOM   6177  C CD  . GLU B 1 414 ? 21.246  -50.573 7.288   1.00 28.29  ? 414 GLU B CD  1 
ATOM   6178  O OE1 . GLU B 1 414 ? 21.650  -50.313 6.141   1.00 30.63  ? 414 GLU B OE1 1 
ATOM   6179  O OE2 . GLU B 1 414 ? 20.207  -50.079 7.740   1.00 29.08  ? 414 GLU B OE2 1 
ATOM   6180  N N   . LEU B 1 415 ? 23.165  -54.763 9.357   1.00 26.15  ? 415 LEU B N   1 
ATOM   6181  C CA  . LEU B 1 415 ? 22.343  -55.955 9.330   1.00 27.43  ? 415 LEU B CA  1 
ATOM   6182  C C   . LEU B 1 415 ? 20.946  -55.594 9.804   1.00 27.74  ? 415 LEU B C   1 
ATOM   6183  O O   . LEU B 1 415 ? 20.735  -54.558 10.436  1.00 32.33  ? 415 LEU B O   1 
ATOM   6184  C CB  . LEU B 1 415 ? 22.916  -57.069 10.222  1.00 24.73  ? 415 LEU B CB  1 
ATOM   6185  C CG  . LEU B 1 415 ? 24.414  -57.370 10.187  1.00 27.33  ? 415 LEU B CG  1 
ATOM   6186  C CD1 . LEU B 1 415 ? 24.736  -58.357 11.266  1.00 26.72  ? 415 LEU B CD1 1 
ATOM   6187  C CD2 . LEU B 1 415 ? 24.809  -57.920 8.851   1.00 29.27  ? 415 LEU B CD2 1 
ATOM   6188  N N   . LEU B 1 416 ? 19.999  -56.482 9.507   1.00 32.38  ? 416 LEU B N   1 
ATOM   6189  C CA  . LEU B 1 416 ? 18.620  -56.375 9.960   1.00 24.03  ? 416 LEU B CA  1 
ATOM   6190  C C   . LEU B 1 416 ? 18.150  -57.742 10.436  1.00 30.21  ? 416 LEU B C   1 
ATOM   6191  O O   . LEU B 1 416 ? 18.232  -58.732 9.695   1.00 28.01  ? 416 LEU B O   1 
ATOM   6192  C CB  . LEU B 1 416 ? 17.734  -55.860 8.833   1.00 28.85  ? 416 LEU B CB  1 
ATOM   6193  C CG  . LEU B 1 416 ? 16.237  -55.983 9.091   1.00 33.39  ? 416 LEU B CG  1 
ATOM   6194  C CD1 . LEU B 1 416 ? 15.802  -54.948 10.139  1.00 28.62  ? 416 LEU B CD1 1 
ATOM   6195  C CD2 . LEU B 1 416 ? 15.481  -55.831 7.769   1.00 24.42  ? 416 LEU B CD2 1 
ATOM   6196  N N   . VAL B 1 417 ? 17.622  -57.785 11.657  1.00 30.71  ? 417 VAL B N   1 
ATOM   6197  C CA  . VAL B 1 417 ? 17.420  -59.019 12.401  1.00 27.15  ? 417 VAL B CA  1 
ATOM   6198  C C   . VAL B 1 417 ? 15.938  -59.172 12.755  1.00 31.57  ? 417 VAL B C   1 
ATOM   6199  O O   . VAL B 1 417 ? 15.312  -58.225 13.245  1.00 30.55  ? 417 VAL B O   1 
ATOM   6200  C CB  . VAL B 1 417 ? 18.304  -59.024 13.664  1.00 26.78  ? 417 VAL B CB  1 
ATOM   6201  C CG1 . VAL B 1 417 ? 18.305  -60.393 14.324  1.00 23.97  ? 417 VAL B CG1 1 
ATOM   6202  C CG2 . VAL B 1 417 ? 19.736  -58.643 13.283  1.00 30.35  ? 417 VAL B CG2 1 
ATOM   6203  N N   . PHE B 1 418 ? 15.386  -60.378 12.545  1.00 29.93  ? 418 PHE B N   1 
ATOM   6204  C CA  . PHE B 1 418 ? 13.973  -60.644 12.805  1.00 29.63  ? 418 PHE B CA  1 
ATOM   6205  C C   . PHE B 1 418 ? 13.780  -61.706 13.875  1.00 30.03  ? 418 PHE B C   1 
ATOM   6206  O O   . PHE B 1 418 ? 14.532  -62.682 13.948  1.00 32.94  ? 418 PHE B O   1 
ATOM   6207  C CB  . PHE B 1 418 ? 13.233  -61.139 11.567  1.00 26.30  ? 418 PHE B CB  1 
ATOM   6208  C CG  . PHE B 1 418 ? 13.246  -60.192 10.439  1.00 29.00  ? 418 PHE B CG  1 
ATOM   6209  C CD1 . PHE B 1 418 ? 12.345  -59.144 10.393  1.00 24.73  ? 418 PHE B CD1 1 
ATOM   6210  C CD2 . PHE B 1 418 ? 14.155  -60.351 9.408   1.00 26.02  ? 418 PHE B CD2 1 
ATOM   6211  C CE1 . PHE B 1 418 ? 12.364  -58.264 9.326   1.00 27.42  ? 418 PHE B CE1 1 
ATOM   6212  C CE2 . PHE B 1 418 ? 14.172  -59.497 8.348   1.00 21.65  ? 418 PHE B CE2 1 
ATOM   6213  C CZ  . PHE B 1 418 ? 13.270  -58.457 8.295   1.00 27.38  ? 418 PHE B CZ  1 
ATOM   6214  N N   . SER B 1 419 ? 12.706  -61.552 14.646  1.00 28.05  ? 419 SER B N   1 
ATOM   6215  C CA  . SER B 1 419 ? 12.302  -62.602 15.566  1.00 29.40  ? 419 SER B CA  1 
ATOM   6216  C C   . SER B 1 419 ? 10.837  -62.422 15.928  1.00 30.77  ? 419 SER B C   1 
ATOM   6217  O O   . SER B 1 419 ? 10.332  -61.300 15.976  1.00 35.48  ? 419 SER B O   1 
ATOM   6218  C CB  . SER B 1 419 ? 13.168  -62.596 16.830  1.00 31.84  ? 419 SER B CB  1 
ATOM   6219  O OG  . SER B 1 419 ? 12.888  -63.718 17.656  1.00 33.02  ? 419 SER B OG  1 
ATOM   6220  N N   . LYS B 1 420 ? 10.171  -63.544 16.207  1.00 31.22  ? 420 LYS B N   1 
ATOM   6221  C CA  . LYS B 1 420 ? 8.824   -63.529 16.759  1.00 34.90  ? 420 LYS B CA  1 
ATOM   6222  C C   . LYS B 1 420 ? 8.803   -63.258 18.257  1.00 30.18  ? 420 LYS B C   1 
ATOM   6223  O O   . LYS B 1 420 ? 7.726   -63.081 18.826  1.00 32.42  ? 420 LYS B O   1 
ATOM   6224  C CB  . LYS B 1 420 ? 8.111   -64.864 16.481  1.00 38.19  ? 420 LYS B CB  1 
ATOM   6225  C CG  . LYS B 1 420 ? 7.884   -65.187 15.002  1.00 40.43  ? 420 LYS B CG  1 
ATOM   6226  C CD  . LYS B 1 420 ? 7.073   -66.471 14.805  1.00 37.92  ? 420 LYS B CD  1 
ATOM   6227  C CE  . LYS B 1 420 ? 7.834   -67.696 15.329  1.00 43.17  ? 420 LYS B CE  1 
ATOM   6228  N NZ  . LYS B 1 420 ? 8.797   -68.311 14.346  1.00 46.72  ? 420 LYS B NZ  1 
ATOM   6229  N N   . ASP B 1 421 ? 9.951   -63.215 18.913  1.00 31.82  ? 421 ASP B N   1 
ATOM   6230  C CA  . ASP B 1 421 ? 10.010  -63.013 20.351  1.00 33.28  ? 421 ASP B CA  1 
ATOM   6231  C C   . ASP B 1 421 ? 11.010  -61.911 20.624  1.00 36.72  ? 421 ASP B C   1 
ATOM   6232  O O   . ASP B 1 421 ? 12.148  -61.985 20.150  1.00 36.50  ? 421 ASP B O   1 
ATOM   6233  C CB  . ASP B 1 421 ? 10.426  -64.300 21.072  1.00 39.40  ? 421 ASP B CB  1 
ATOM   6234  C CG  . ASP B 1 421 ? 10.157  -64.248 22.555  1.00 38.30  ? 421 ASP B CG  1 
ATOM   6235  O OD1 . ASP B 1 421 ? 9.023   -64.572 22.966  1.00 40.74  ? 421 ASP B OD1 1 
ATOM   6236  O OD2 . ASP B 1 421 ? 11.079  -63.875 23.312  1.00 41.44  ? 421 ASP B OD2 1 
ATOM   6237  N N   . TRP B 1 422 ? 10.598  -60.884 21.367  1.00 37.43  ? 422 TRP B N   1 
ATOM   6238  C CA  . TRP B 1 422 ? 11.493  -59.744 21.533  1.00 42.18  ? 422 TRP B CA  1 
ATOM   6239  C C   . TRP B 1 422 ? 12.771  -60.158 22.259  1.00 44.59  ? 422 TRP B C   1 
ATOM   6240  O O   . TRP B 1 422 ? 13.885  -59.857 21.805  1.00 40.73  ? 422 TRP B O   1 
ATOM   6241  C CB  . TRP B 1 422 ? 10.806  -58.588 22.270  1.00 39.67  ? 422 TRP B CB  1 
ATOM   6242  C CG  . TRP B 1 422 ? 11.803  -57.486 22.538  1.00 43.94  ? 422 TRP B CG  1 
ATOM   6243  C CD1 . TRP B 1 422 ? 12.351  -57.159 23.746  1.00 48.49  ? 422 TRP B CD1 1 
ATOM   6244  C CD2 . TRP B 1 422 ? 12.418  -56.613 21.572  1.00 46.14  ? 422 TRP B CD2 1 
ATOM   6245  N NE1 . TRP B 1 422 ? 13.256  -56.136 23.596  1.00 51.57  ? 422 TRP B NE1 1 
ATOM   6246  C CE2 . TRP B 1 422 ? 13.319  -55.784 22.273  1.00 49.86  ? 422 TRP B CE2 1 
ATOM   6247  C CE3 . TRP B 1 422 ? 12.299  -56.457 20.182  1.00 48.00  ? 422 TRP B CE3 1 
ATOM   6248  C CZ2 . TRP B 1 422 ? 14.089  -54.801 21.635  1.00 50.76  ? 422 TRP B CZ2 1 
ATOM   6249  C CZ3 . TRP B 1 422 ? 13.066  -55.468 19.547  1.00 46.27  ? 422 TRP B CZ3 1 
ATOM   6250  C CH2 . TRP B 1 422 ? 13.948  -54.658 20.276  1.00 48.92  ? 422 TRP B CH2 1 
ATOM   6251  N N   . ASP B 1 423 ? 12.632  -60.860 23.386  1.00 40.40  ? 423 ASP B N   1 
ATOM   6252  C CA  . ASP B 1 423 ? 13.814  -61.251 24.147  1.00 43.33  ? 423 ASP B CA  1 
ATOM   6253  C C   . ASP B 1 423 ? 14.722  -62.161 23.333  1.00 41.94  ? 423 ASP B C   1 
ATOM   6254  O O   . ASP B 1 423 ? 15.947  -62.158 23.523  1.00 32.39  ? 423 ASP B O   1 
ATOM   6255  C CB  . ASP B 1 423 ? 13.394  -61.936 25.444  1.00 45.82  ? 423 ASP B CB  1 
ATOM   6256  C CG  . ASP B 1 423 ? 13.201  -60.954 26.580  1.00 52.37  ? 423 ASP B CG  1 
ATOM   6257  O OD1 . ASP B 1 423 ? 14.052  -60.052 26.745  1.00 54.11  ? 423 ASP B OD1 1 
ATOM   6258  O OD2 . ASP B 1 423 ? 12.197  -61.082 27.306  1.00 58.37  ? 423 ASP B OD2 1 
ATOM   6259  N N   . ARG B 1 424 ? 14.134  -62.936 22.423  1.00 38.49  ? 424 ARG B N   1 
ATOM   6260  C CA  . ARG B 1 424 ? 14.916  -63.797 21.548  1.00 37.71  ? 424 ARG B CA  1 
ATOM   6261  C C   . ARG B 1 424 ? 15.743  -62.957 20.584  1.00 39.75  ? 424 ARG B C   1 
ATOM   6262  O O   . ARG B 1 424 ? 16.945  -63.188 20.410  1.00 37.88  ? 424 ARG B O   1 
ATOM   6263  C CB  . ARG B 1 424 ? 13.960  -64.733 20.810  1.00 38.67  ? 424 ARG B CB  1 
ATOM   6264  C CG  . ARG B 1 424 ? 14.550  -65.906 20.089  1.00 40.76  ? 424 ARG B CG  1 
ATOM   6265  C CD  . ARG B 1 424 ? 13.570  -67.070 20.171  1.00 48.04  ? 424 ARG B CD  1 
ATOM   6266  N NE  . ARG B 1 424 ? 12.609  -67.088 19.074  1.00 42.69  ? 424 ARG B NE  1 
ATOM   6267  C CZ  . ARG B 1 424 ? 11.311  -67.314 19.229  1.00 45.83  ? 424 ARG B CZ  1 
ATOM   6268  N NH1 . ARG B 1 424 ? 10.792  -67.571 20.420  1.00 48.22  ? 424 ARG B NH1 1 
ATOM   6269  N NH2 . ARG B 1 424 ? 10.513  -67.279 18.164  1.00 43.92  ? 424 ARG B NH2 1 
ATOM   6270  N N   . LEU B 1 425 ? 15.117  -61.939 19.988  1.00 41.91  ? 425 LEU B N   1 
ATOM   6271  C CA  . LEU B 1 425 ? 15.817  -61.071 19.052  1.00 35.90  ? 425 LEU B CA  1 
ATOM   6272  C C   . LEU B 1 425 ? 16.964  -60.341 19.739  1.00 38.31  ? 425 LEU B C   1 
ATOM   6273  O O   . LEU B 1 425 ? 18.046  -60.185 19.165  1.00 40.30  ? 425 LEU B O   1 
ATOM   6274  C CB  . LEU B 1 425 ? 14.827  -60.088 18.423  1.00 34.41  ? 425 LEU B CB  1 
ATOM   6275  C CG  . LEU B 1 425 ? 15.377  -58.855 17.714  1.00 38.16  ? 425 LEU B CG  1 
ATOM   6276  C CD1 . LEU B 1 425 ? 15.906  -59.287 16.423  1.00 32.15  ? 425 LEU B CD1 1 
ATOM   6277  C CD2 . LEU B 1 425 ? 14.269  -57.839 17.468  1.00 39.16  ? 425 LEU B CD2 1 
ATOM   6278  N N   . THR B 1 426 ? 16.750  -59.891 20.974  1.00 41.18  ? 426 THR B N   1 
ATOM   6279  C CA  . THR B 1 426 ? 17.845  -59.312 21.742  1.00 36.96  ? 426 THR B CA  1 
ATOM   6280  C C   . THR B 1 426 ? 18.974  -60.329 21.933  1.00 40.08  ? 426 THR B C   1 
ATOM   6281  O O   . THR B 1 426 ? 20.156  -60.000 21.772  1.00 35.23  ? 426 THR B O   1 
ATOM   6282  C CB  . THR B 1 426 ? 17.310  -58.794 23.082  1.00 43.39  ? 426 THR B CB  1 
ATOM   6283  O OG1 . THR B 1 426 ? 16.653  -57.529 22.884  1.00 44.47  ? 426 THR B OG1 1 
ATOM   6284  C CG2 . THR B 1 426 ? 18.431  -58.618 24.100  1.00 46.23  ? 426 THR B CG2 1 
ATOM   6285  N N   . ALA B 1 427 ? 18.630  -61.585 22.228  1.00 37.72  ? 427 ALA B N   1 
ATOM   6286  C CA  . ALA B 1 427 ? 19.664  -62.614 22.314  1.00 40.83  ? 427 ALA B CA  1 
ATOM   6287  C C   . ALA B 1 427 ? 20.415  -62.763 20.991  1.00 40.80  ? 427 ALA B C   1 
ATOM   6288  O O   . ALA B 1 427 ? 21.644  -62.899 20.981  1.00 39.05  ? 427 ALA B O   1 
ATOM   6289  C CB  . ALA B 1 427 ? 19.057  -63.955 22.746  1.00 29.20  ? 427 ALA B CB  1 
ATOM   6290  N N   . MET B 1 428 ? 19.695  -62.737 19.863  1.00 40.69  ? 428 MET B N   1 
ATOM   6291  C CA  . MET B 1 428 ? 20.346  -62.922 18.570  1.00 37.91  ? 428 MET B CA  1 
ATOM   6292  C C   . MET B 1 428 ? 21.305  -61.773 18.270  1.00 39.33  ? 428 MET B C   1 
ATOM   6293  O O   . MET B 1 428 ? 22.419  -61.992 17.767  1.00 36.93  ? 428 MET B O   1 
ATOM   6294  C CB  . MET B 1 428 ? 19.283  -63.056 17.474  1.00 37.00  ? 428 MET B CB  1 
ATOM   6295  C CG  . MET B 1 428 ? 18.354  -64.246 17.693  1.00 44.08  ? 428 MET B CG  1 
ATOM   6296  S SD  . MET B 1 428 ? 17.005  -64.456 16.510  1.00 53.22  ? 428 MET B SD  1 
ATOM   6297  C CE  . MET B 1 428 ? 17.637  -63.588 15.110  1.00 34.15  ? 428 MET B CE  1 
ATOM   6298  N N   . LYS B 1 429 ? 20.886  -60.539 18.567  1.00 36.61  ? 429 LYS B N   1 
ATOM   6299  C CA  . LYS B 1 429 ? 21.744  -59.390 18.315  1.00 34.14  ? 429 LYS B CA  1 
ATOM   6300  C C   . LYS B 1 429 ? 23.042  -59.509 19.097  1.00 38.80  ? 429 LYS B C   1 
ATOM   6301  O O   . LYS B 1 429 ? 24.112  -59.136 18.603  1.00 35.68  ? 429 LYS B O   1 
ATOM   6302  C CB  . LYS B 1 429 ? 21.010  -58.097 18.677  1.00 40.43  ? 429 LYS B CB  1 
ATOM   6303  C CG  . LYS B 1 429 ? 19.701  -57.910 17.932  1.00 38.43  ? 429 LYS B CG  1 
ATOM   6304  C CD  . LYS B 1 429 ? 19.479  -56.468 17.567  1.00 34.41  ? 429 LYS B CD  1 
ATOM   6305  C CE  . LYS B 1 429 ? 18.972  -55.684 18.767  1.00 37.30  ? 429 LYS B CE  1 
ATOM   6306  N NZ  . LYS B 1 429 ? 19.470  -54.285 18.666  1.00 42.03  ? 429 LYS B NZ  1 
ATOM   6307  N N   . ASP B 1 430 ? 22.969  -60.050 20.315  1.00 38.63  ? 430 ASP B N   1 
ATOM   6308  C CA  . ASP B 1 430 ? 24.180  -60.243 21.099  1.00 41.94  ? 430 ASP B CA  1 
ATOM   6309  C C   . ASP B 1 430 ? 25.072  -61.317 20.494  1.00 37.73  ? 430 ASP B C   1 
ATOM   6310  O O   . ASP B 1 430 ? 26.303  -61.193 20.544  1.00 35.08  ? 430 ASP B O   1 
ATOM   6311  C CB  . ASP B 1 430 ? 23.819  -60.578 22.545  1.00 43.29  ? 430 ASP B CB  1 
ATOM   6312  C CG  . ASP B 1 430 ? 23.442  -59.345 23.343  1.00 50.01  ? 430 ASP B CG  1 
ATOM   6313  O OD1 . ASP B 1 430 ? 23.888  -58.231 22.975  1.00 54.94  ? 430 ASP B OD1 1 
ATOM   6314  O OD2 . ASP B 1 430 ? 22.716  -59.488 24.346  1.00 52.27  ? 430 ASP B OD2 1 
ATOM   6315  N N   . GLU B 1 431 ? 24.479  -62.358 19.898  1.00 37.59  ? 431 GLU B N   1 
ATOM   6316  C CA  . GLU B 1 431 ? 25.289  -63.364 19.208  1.00 40.01  ? 431 GLU B CA  1 
ATOM   6317  C C   . GLU B 1 431 ? 26.000  -62.762 18.002  1.00 37.17  ? 431 GLU B C   1 
ATOM   6318  O O   . GLU B 1 431 ? 27.172  -63.066 17.745  1.00 41.04  ? 431 GLU B O   1 
ATOM   6319  C CB  . GLU B 1 431 ? 24.424  -64.556 18.783  1.00 38.65  ? 431 GLU B CB  1 
ATOM   6320  C CG  . GLU B 1 431 ? 23.681  -65.222 19.927  1.00 42.27  ? 431 GLU B CG  1 
ATOM   6321  C CD  . GLU B 1 431 ? 24.539  -66.228 20.644  1.00 53.33  ? 431 GLU B CD  1 
ATOM   6322  O OE1 . GLU B 1 431 ? 24.846  -67.287 20.046  1.00 53.65  ? 431 GLU B OE1 1 
ATOM   6323  O OE2 . GLU B 1 431 ? 24.936  -65.947 21.795  1.00 49.48  ? 431 GLU B OE2 1 
ATOM   6324  N N   . ILE B 1 432 ? 25.311  -61.904 17.249  1.00 33.57  ? 432 ILE B N   1 
ATOM   6325  C CA  . ILE B 1 432 ? 25.975  -61.200 16.161  1.00 29.50  ? 432 ILE B CA  1 
ATOM   6326  C C   . ILE B 1 432 ? 27.133  -60.372 16.692  1.00 32.40  ? 432 ILE B C   1 
ATOM   6327  O O   . ILE B 1 432 ? 28.213  -60.337 16.091  1.00 40.42  ? 432 ILE B O   1 
ATOM   6328  C CB  . ILE B 1 432 ? 24.964  -60.335 15.389  1.00 29.60  ? 432 ILE B CB  1 
ATOM   6329  C CG1 . ILE B 1 432 ? 23.890  -61.223 14.744  1.00 36.41  ? 432 ILE B CG1 1 
ATOM   6330  C CG2 . ILE B 1 432 ? 25.680  -59.493 14.361  1.00 25.59  ? 432 ILE B CG2 1 
ATOM   6331  C CD1 . ILE B 1 432 ? 22.601  -60.474 14.353  1.00 27.92  ? 432 ILE B CD1 1 
ATOM   6332  N N   . ALA B 1 433 ? 26.929  -59.693 17.825  1.00 37.40  ? 433 ALA B N   1 
ATOM   6333  C CA  . ALA B 1 433 ? 27.972  -58.846 18.399  1.00 37.30  ? 433 ALA B CA  1 
ATOM   6334  C C   . ALA B 1 433 ? 29.199  -59.661 18.750  1.00 40.68  ? 433 ALA B C   1 
ATOM   6335  O O   . ALA B 1 433 ? 30.328  -59.296 18.404  1.00 40.77  ? 433 ALA B O   1 
ATOM   6336  C CB  . ALA B 1 433 ? 27.450  -58.138 19.642  1.00 38.21  ? 433 ALA B CB  1 
ATOM   6337  N N   . THR B 1 434 ? 28.995  -60.765 19.456  1.00 37.73  ? 434 THR B N   1 
ATOM   6338  C CA  . THR B 1 434 ? 30.106  -61.651 19.752  1.00 38.55  ? 434 THR B CA  1 
ATOM   6339  C C   . THR B 1 434 ? 30.775  -62.128 18.469  1.00 41.23  ? 434 THR B C   1 
ATOM   6340  O O   . THR B 1 434 ? 31.977  -61.920 18.268  1.00 42.20  ? 434 THR B O   1 
ATOM   6341  C CB  . THR B 1 434 ? 29.599  -62.833 20.570  1.00 41.00  ? 434 THR B CB  1 
ATOM   6342  O OG1 . THR B 1 434 ? 29.011  -62.347 21.791  1.00 33.41  ? 434 THR B OG1 1 
ATOM   6343  C CG2 . THR B 1 434 ? 30.752  -63.793 20.872  1.00 43.02  ? 434 THR B CG2 1 
ATOM   6344  N N   . THR B 1 435 ? 29.989  -62.706 17.556  1.00 38.08  ? 435 THR B N   1 
ATOM   6345  C CA  . THR B 1 435 ? 30.549  -63.489 16.461  1.00 37.64  ? 435 THR B CA  1 
ATOM   6346  C C   . THR B 1 435 ? 31.086  -62.618 15.329  1.00 38.99  ? 435 THR B C   1 
ATOM   6347  O O   . THR B 1 435 ? 32.122  -62.940 14.739  1.00 43.07  ? 435 THR B O   1 
ATOM   6348  C CB  . THR B 1 435 ? 29.494  -64.464 15.940  1.00 40.26  ? 435 THR B CB  1 
ATOM   6349  O OG1 . THR B 1 435 ? 28.992  -65.242 17.035  1.00 45.46  ? 435 THR B OG1 1 
ATOM   6350  C CG2 . THR B 1 435 ? 30.078  -65.394 14.911  1.00 33.25  ? 435 THR B CG2 1 
ATOM   6351  N N   . ALA B 1 436 ? 30.410  -61.527 15.001  1.00 36.93  ? 436 ALA B N   1 
ATOM   6352  C CA  . ALA B 1 436 ? 30.868  -60.664 13.922  1.00 36.50  ? 436 ALA B CA  1 
ATOM   6353  C C   . ALA B 1 436 ? 31.585  -59.416 14.419  1.00 37.33  ? 436 ALA B C   1 
ATOM   6354  O O   . ALA B 1 436 ? 32.317  -58.787 13.647  1.00 37.94  ? 436 ALA B O   1 
ATOM   6355  C CB  . ALA B 1 436 ? 29.686  -60.243 13.035  1.00 33.88  ? 436 ALA B CB  1 
ATOM   6356  N N   . GLY B 1 437 ? 31.396  -59.047 15.679  1.00 37.34  ? 437 GLY B N   1 
ATOM   6357  C CA  . GLY B 1 437 ? 32.015  -57.849 16.205  1.00 40.96  ? 437 GLY B CA  1 
ATOM   6358  C C   . GLY B 1 437 ? 31.281  -56.571 15.849  1.00 39.64  ? 437 GLY B C   1 
ATOM   6359  O O   . GLY B 1 437 ? 30.701  -56.457 14.763  1.00 41.87  ? 437 GLY B O   1 
ATOM   6360  N N   . THR B 1 438 ? 31.300  -55.599 16.759  1.00 42.94  ? 438 THR B N   1 
ATOM   6361  C CA  . THR B 1 438 ? 30.816  -54.255 16.483  1.00 43.48  ? 438 THR B CA  1 
ATOM   6362  C C   . THR B 1 438 ? 31.868  -53.239 16.908  1.00 43.90  ? 438 THR B C   1 
ATOM   6363  O O   . THR B 1 438 ? 32.857  -53.573 17.566  1.00 41.54  ? 438 THR B O   1 
ATOM   6364  C CB  . THR B 1 438 ? 29.484  -53.972 17.187  1.00 42.93  ? 438 THR B CB  1 
ATOM   6365  O OG1 . THR B 1 438 ? 29.623  -54.194 18.596  1.00 44.34  ? 438 THR B OG1 1 
ATOM   6366  C CG2 . THR B 1 438 ? 28.369  -54.858 16.614  1.00 44.13  ? 438 THR B CG2 1 
ATOM   6367  N N   . LEU B 1 439 ? 31.653  -51.990 16.494  1.00 46.60  ? 439 LEU B N   1 
ATOM   6368  C CA  . LEU B 1 439 ? 32.481  -50.862 16.898  1.00 45.13  ? 439 LEU B CA  1 
ATOM   6369  C C   . LEU B 1 439 ? 31.895  -50.186 18.142  1.00 48.69  ? 439 LEU B C   1 
ATOM   6370  O O   . LEU B 1 439 ? 30.691  -50.254 18.405  1.00 52.86  ? 439 LEU B O   1 
ATOM   6371  C CB  . LEU B 1 439 ? 32.611  -49.862 15.745  1.00 40.45  ? 439 LEU B CB  1 
ATOM   6372  C CG  . LEU B 1 439 ? 32.939  -50.468 14.374  1.00 41.85  ? 439 LEU B CG  1 
ATOM   6373  C CD1 . LEU B 1 439 ? 32.421  -49.595 13.232  1.00 37.88  ? 439 LEU B CD1 1 
ATOM   6374  C CD2 . LEU B 1 439 ? 34.453  -50.727 14.205  1.00 40.93  ? 439 LEU B CD2 1 
ATOM   6375  N N   . SER B 1 440 ? 32.760  -49.528 18.910  1.00 56.65  ? 440 SER B N   1 
ATOM   6376  C CA  . SER B 1 440 ? 32.371  -49.035 20.235  1.00 57.25  ? 440 SER B CA  1 
ATOM   6377  C C   . SER B 1 440 ? 32.905  -47.641 20.575  1.00 62.28  ? 440 SER B C   1 
ATOM   6378  O O   . SER B 1 440 ? 33.967  -47.230 20.097  1.00 63.86  ? 440 SER B O   1 
ATOM   6379  C CB  . SER B 1 440 ? 32.847  -50.021 21.294  1.00 59.54  ? 440 SER B CB  1 
ATOM   6380  O OG  . SER B 1 440 ? 34.253  -50.197 21.187  1.00 65.05  ? 440 SER B OG  1 
ATOM   6381  N N   . MET C 1 1   ? 61.013  -16.171 -14.446 1.00 63.54  ? 1   MET C N   1 
ATOM   6382  C CA  . MET C 1 1   ? 60.843  -17.612 -14.633 1.00 66.03  ? 1   MET C CA  1 
ATOM   6383  C C   . MET C 1 1   ? 59.574  -18.086 -13.904 1.00 60.81  ? 1   MET C C   1 
ATOM   6384  O O   . MET C 1 1   ? 59.642  -18.515 -12.738 1.00 52.30  ? 1   MET C O   1 
ATOM   6385  C CB  . MET C 1 1   ? 62.086  -18.365 -14.129 1.00 60.94  ? 1   MET C CB  1 
ATOM   6386  C CG  . MET C 1 1   ? 62.263  -19.774 -14.683 1.00 59.70  ? 1   MET C CG  1 
ATOM   6387  S SD  . MET C 1 1   ? 62.444  -21.050 -13.406 1.00 72.96  ? 1   MET C SD  1 
ATOM   6388  C CE  . MET C 1 1   ? 60.724  -21.390 -13.000 1.00 42.75  ? 1   MET C CE  1 
ATOM   6389  N N   . PRO C 1 2   ? 58.421  -17.996 -14.577 1.00 50.69  ? 2   PRO C N   1 
ATOM   6390  C CA  . PRO C 1 2   ? 57.157  -18.310 -13.904 1.00 42.09  ? 2   PRO C CA  1 
ATOM   6391  C C   . PRO C 1 2   ? 57.023  -19.791 -13.607 1.00 44.77  ? 2   PRO C C   1 
ATOM   6392  O O   . PRO C 1 2   ? 57.611  -20.653 -14.272 1.00 45.46  ? 2   PRO C O   1 
ATOM   6393  C CB  . PRO C 1 2   ? 56.084  -17.840 -14.894 1.00 44.89  ? 2   PRO C CB  1 
ATOM   6394  C CG  . PRO C 1 2   ? 56.762  -17.773 -16.200 1.00 46.80  ? 2   PRO C CG  1 
ATOM   6395  C CD  . PRO C 1 2   ? 58.216  -17.511 -15.952 1.00 46.48  ? 2   PRO C CD  1 
ATOM   6396  N N   . LYS C 1 3   ? 56.239  -20.077 -12.577 1.00 39.47  ? 3   LYS C N   1 
ATOM   6397  C CA  . LYS C 1 3   ? 55.978  -21.437 -12.154 1.00 35.01  ? 3   LYS C CA  1 
ATOM   6398  C C   . LYS C 1 3   ? 54.485  -21.710 -12.228 1.00 30.32  ? 3   LYS C C   1 
ATOM   6399  O O   . LYS C 1 3   ? 53.658  -20.798 -12.238 1.00 34.93  ? 3   LYS C O   1 
ATOM   6400  C CB  . LYS C 1 3   ? 56.492  -21.692 -10.727 1.00 33.78  ? 3   LYS C CB  1 
ATOM   6401  C CG  . LYS C 1 3   ? 55.746  -20.927 -9.635  1.00 30.44  ? 3   LYS C CG  1 
ATOM   6402  C CD  . LYS C 1 3   ? 56.508  -20.971 -8.314  1.00 30.52  ? 3   LYS C CD  1 
ATOM   6403  C CE  . LYS C 1 3   ? 55.973  -19.954 -7.302  1.00 27.20  ? 3   LYS C CE  1 
ATOM   6404  N NZ  . LYS C 1 3   ? 56.508  -18.577 -7.544  1.00 29.32  ? 3   LYS C NZ  1 
ATOM   6405  N N   . ILE C 1 4   ? 54.153  -22.984 -12.321 1.00 30.42  ? 4   ILE C N   1 
ATOM   6406  C CA  . ILE C 1 4   ? 52.790  -23.453 -12.162 1.00 29.90  ? 4   ILE C CA  1 
ATOM   6407  C C   . ILE C 1 4   ? 52.644  -23.926 -10.723 1.00 30.85  ? 4   ILE C C   1 
ATOM   6408  O O   . ILE C 1 4   ? 53.318  -24.876 -10.308 1.00 31.70  ? 4   ILE C O   1 
ATOM   6409  C CB  . ILE C 1 4   ? 52.471  -24.577 -13.151 1.00 25.94  ? 4   ILE C CB  1 
ATOM   6410  C CG1 . ILE C 1 4   ? 52.675  -24.104 -14.597 1.00 34.83  ? 4   ILE C CG1 1 
ATOM   6411  C CG2 . ILE C 1 4   ? 51.075  -25.061 -12.947 1.00 28.26  ? 4   ILE C CG2 1 
ATOM   6412  C CD1 . ILE C 1 4   ? 52.430  -25.231 -15.622 1.00 28.87  ? 4   ILE C CD1 1 
ATOM   6413  N N   . ILE C 1 5   ? 51.797  -23.246 -9.958  1.00 26.03  ? 5   ILE C N   1 
ATOM   6414  C CA  . ILE C 1 5   ? 51.554  -23.570 -8.557  1.00 30.00  ? 5   ILE C CA  1 
ATOM   6415  C C   . ILE C 1 5   ? 50.436  -24.594 -8.500  1.00 31.24  ? 5   ILE C C   1 
ATOM   6416  O O   . ILE C 1 5   ? 49.307  -24.297 -8.901  1.00 28.71  ? 5   ILE C O   1 
ATOM   6417  C CB  . ILE C 1 5   ? 51.187  -22.315 -7.758  1.00 28.84  ? 5   ILE C CB  1 
ATOM   6418  C CG1 . ILE C 1 5   ? 52.115  -21.165 -8.135  1.00 33.05  ? 5   ILE C CG1 1 
ATOM   6419  C CG2 . ILE C 1 5   ? 51.245  -22.599 -6.285  1.00 28.96  ? 5   ILE C CG2 1 
ATOM   6420  C CD1 . ILE C 1 5   ? 51.681  -19.847 -7.551  1.00 34.92  ? 5   ILE C CD1 1 
ATOM   6421  N N   . LEU C 1 6   ? 50.743  -25.798 -8.003  1.00 28.44  ? 6   LEU C N   1 
ATOM   6422  C CA  . LEU C 1 6   ? 49.896  -26.969 -8.225  1.00 27.68  ? 6   LEU C CA  1 
ATOM   6423  C C   . LEU C 1 6   ? 49.588  -27.685 -6.917  1.00 29.51  ? 6   LEU C C   1 
ATOM   6424  O O   . LEU C 1 6   ? 50.318  -28.597 -6.506  1.00 29.15  ? 6   LEU C O   1 
ATOM   6425  C CB  . LEU C 1 6   ? 50.554  -27.925 -9.221  1.00 30.67  ? 6   LEU C CB  1 
ATOM   6426  C CG  . LEU C 1 6   ? 49.736  -29.158 -9.621  1.00 30.18  ? 6   LEU C CG  1 
ATOM   6427  C CD1 . LEU C 1 6   ? 48.758  -28.800 -10.746 1.00 35.07  ? 6   LEU C CD1 1 
ATOM   6428  C CD2 . LEU C 1 6   ? 50.615  -30.345 -10.008 1.00 24.13  ? 6   LEU C CD2 1 
ATOM   6429  N N   . PRO C 1 7   ? 48.495  -27.334 -6.262  1.00 27.30  ? 7   PRO C N   1 
ATOM   6430  C CA  . PRO C 1 7   ? 48.170  -27.903 -4.947  1.00 29.79  ? 7   PRO C CA  1 
ATOM   6431  C C   . PRO C 1 7   ? 47.484  -29.263 -5.051  1.00 33.29  ? 7   PRO C C   1 
ATOM   6432  O O   . PRO C 1 7   ? 46.331  -29.442 -4.645  1.00 33.05  ? 7   PRO C O   1 
ATOM   6433  C CB  . PRO C 1 7   ? 47.245  -26.828 -4.358  1.00 30.22  ? 7   PRO C CB  1 
ATOM   6434  C CG  . PRO C 1 7   ? 46.457  -26.381 -5.551  1.00 30.03  ? 7   PRO C CG  1 
ATOM   6435  C CD  . PRO C 1 7   ? 47.479  -26.356 -6.695  1.00 32.81  ? 7   PRO C CD  1 
ATOM   6436  N N   . ASN C 1 8   ? 48.192  -30.246 -5.594  1.00 28.47  ? 8   ASN C N   1 
ATOM   6437  C CA  . ASN C 1 8   ? 47.572  -31.554 -5.749  1.00 33.74  ? 8   ASN C CA  1 
ATOM   6438  C C   . ASN C 1 8   ? 47.357  -32.225 -4.388  1.00 32.21  ? 8   ASN C C   1 
ATOM   6439  O O   . ASN C 1 8   ? 48.203  -32.955 -3.914  1.00 29.98  ? 8   ASN C O   1 
ATOM   6440  C CB  . ASN C 1 8   ? 48.370  -32.464 -6.723  1.00 32.85  ? 8   ASN C CB  1 
ATOM   6441  C CG  . ASN C 1 8   ? 49.898  -32.396 -6.538  1.00 37.70  ? 8   ASN C CG  1 
ATOM   6442  O OD1 . ASN C 1 8   ? 50.461  -31.368 -6.168  1.00 34.54  ? 8   ASN C OD1 1 
ATOM   6443  N ND2 . ASN C 1 8   ? 50.567  -33.517 -6.791  1.00 24.55  ? 8   ASN C ND2 1 
ATOM   6444  N N   . SER C 1 29  ? 33.524  -27.889 -2.872  1.00 66.83  ? 29  SER C N   1 
ATOM   6445  C CA  . SER C 1 29  ? 34.150  -27.006 -3.849  1.00 62.38  ? 29  SER C CA  1 
ATOM   6446  C C   . SER C 1 29  ? 33.586  -25.588 -3.788  1.00 56.91  ? 29  SER C C   1 
ATOM   6447  O O   . SER C 1 29  ? 34.053  -24.707 -4.510  1.00 56.24  ? 29  SER C O   1 
ATOM   6448  C CB  . SER C 1 29  ? 33.978  -27.569 -5.258  1.00 64.05  ? 29  SER C CB  1 
ATOM   6449  O OG  . SER C 1 29  ? 32.607  -27.728 -5.579  1.00 69.45  ? 29  SER C OG  1 
ATOM   6450  N N   . SER C 1 30  ? 32.574  -25.373 -2.938  1.00 57.94  ? 30  SER C N   1 
ATOM   6451  C CA  . SER C 1 30  ? 32.099  -24.021 -2.647  1.00 55.02  ? 30  SER C CA  1 
ATOM   6452  C C   . SER C 1 30  ? 33.035  -23.279 -1.697  1.00 48.74  ? 30  SER C C   1 
ATOM   6453  O O   . SER C 1 30  ? 32.882  -22.065 -1.498  1.00 45.04  ? 30  SER C O   1 
ATOM   6454  C CB  . SER C 1 30  ? 30.679  -24.067 -2.067  1.00 49.70  ? 30  SER C CB  1 
ATOM   6455  O OG  . SER C 1 30  ? 30.590  -24.911 -0.927  1.00 48.03  ? 30  SER C OG  1 
ATOM   6456  N N   . THR C 1 31  ? 34.006  -23.982 -1.131  1.00 41.21  ? 31  THR C N   1 
ATOM   6457  C CA  . THR C 1 31  ? 35.021  -23.410 -0.272  1.00 38.54  ? 31  THR C CA  1 
ATOM   6458  C C   . THR C 1 31  ? 36.140  -22.783 -1.109  1.00 39.13  ? 31  THR C C   1 
ATOM   6459  O O   . THR C 1 31  ? 36.153  -22.867 -2.341  1.00 43.94  ? 31  THR C O   1 
ATOM   6460  C CB  . THR C 1 31  ? 35.543  -24.499 0.647   1.00 40.80  ? 31  THR C CB  1 
ATOM   6461  O OG1 . THR C 1 31  ? 35.650  -25.707 -0.113  1.00 46.50  ? 31  THR C OG1 1 
ATOM   6462  C CG2 . THR C 1 31  ? 34.579  -24.725 1.801   1.00 38.24  ? 31  THR C CG2 1 
ATOM   6463  N N   . ASP C 1 32  ? 37.102  -22.134 -0.446  1.00 33.32  ? 32  ASP C N   1 
ATOM   6464  C CA  . ASP C 1 32  ? 38.255  -21.584 -1.160  1.00 36.97  ? 32  ASP C CA  1 
ATOM   6465  C C   . ASP C 1 32  ? 39.566  -21.994 -0.490  1.00 31.47  ? 32  ASP C C   1 
ATOM   6466  O O   . ASP C 1 32  ? 40.532  -21.226 -0.449  1.00 30.83  ? 32  ASP C O   1 
ATOM   6467  C CB  . ASP C 1 32  ? 38.152  -20.057 -1.316  1.00 33.47  ? 32  ASP C CB  1 
ATOM   6468  C CG  . ASP C 1 32  ? 38.138  -19.304 0.020   1.00 32.35  ? 32  ASP C CG  1 
ATOM   6469  O OD1 . ASP C 1 32  ? 38.031  -19.951 1.079   1.00 31.09  ? 32  ASP C OD1 1 
ATOM   6470  O OD2 . ASP C 1 32  ? 38.229  -18.047 0.004   1.00 34.11  ? 32  ASP C OD2 1 
ATOM   6471  N N   . THR C 1 33  ? 39.632  -23.245 -0.023  1.00 31.49  ? 33  THR C N   1 
ATOM   6472  C CA  . THR C 1 33  ? 40.768  -23.716 0.770   1.00 30.05  ? 33  THR C CA  1 
ATOM   6473  C C   . THR C 1 33  ? 42.093  -23.566 0.028   1.00 33.78  ? 33  THR C C   1 
ATOM   6474  O O   . THR C 1 33  ? 43.125  -23.278 0.646   1.00 30.49  ? 33  THR C O   1 
ATOM   6475  C CB  . THR C 1 33  ? 40.564  -25.181 1.166   1.00 37.26  ? 33  THR C CB  1 
ATOM   6476  O OG1 . THR C 1 33  ? 39.303  -25.337 1.835   1.00 42.80  ? 33  THR C OG1 1 
ATOM   6477  C CG2 . THR C 1 33  ? 41.676  -25.648 2.091   1.00 31.47  ? 33  THR C CG2 1 
ATOM   6478  N N   . THR C 1 34  ? 42.101  -23.768 -1.286  1.00 29.21  ? 34  THR C N   1 
ATOM   6479  C CA  . THR C 1 34  ? 43.361  -23.736 -2.018  1.00 31.77  ? 34  THR C CA  1 
ATOM   6480  C C   . THR C 1 34  ? 43.732  -22.338 -2.512  1.00 31.42  ? 34  THR C C   1 
ATOM   6481  O O   . THR C 1 34  ? 44.709  -22.195 -3.255  1.00 33.61  ? 34  THR C O   1 
ATOM   6482  C CB  . THR C 1 34  ? 43.314  -24.717 -3.192  1.00 38.81  ? 34  THR C CB  1 
ATOM   6483  O OG1 . THR C 1 34  ? 42.710  -24.073 -4.316  1.00 40.43  ? 34  THR C OG1 1 
ATOM   6484  C CG2 . THR C 1 34  ? 42.485  -25.910 -2.826  1.00 34.78  ? 34  THR C CG2 1 
ATOM   6485  N N   . ALA C 1 35  ? 42.988  -21.307 -2.105  1.00 26.78  ? 35  ALA C N   1 
ATOM   6486  C CA  . ALA C 1 35  ? 43.293  -19.936 -2.509  1.00 27.46  ? 35  ALA C CA  1 
ATOM   6487  C C   . ALA C 1 35  ? 44.479  -19.379 -1.751  1.00 27.07  ? 35  ALA C C   1 
ATOM   6488  O O   . ALA C 1 35  ? 45.172  -18.483 -2.254  1.00 27.27  ? 35  ALA C O   1 
ATOM   6489  C CB  . ALA C 1 35  ? 42.092  -19.025 -2.254  1.00 33.11  ? 35  ALA C CB  1 
ATOM   6490  N N   . ARG C 1 36  ? 44.695  -19.876 -0.531  1.00 23.62  ? 36  ARG C N   1 
ATOM   6491  C CA  . ARG C 1 36  ? 45.880  -19.513 0.232   1.00 25.69  ? 36  ARG C CA  1 
ATOM   6492  C C   . ARG C 1 36  ? 47.132  -19.596 -0.615  1.00 22.92  ? 36  ARG C C   1 
ATOM   6493  O O   . ARG C 1 36  ? 48.047  -18.798 -0.429  1.00 24.38  ? 36  ARG C O   1 
ATOM   6494  C CB  . ARG C 1 36  ? 46.021  -20.401 1.482   1.00 27.04  ? 36  ARG C CB  1 
ATOM   6495  C CG  . ARG C 1 36  ? 46.401  -21.885 1.272   1.00 23.56  ? 36  ARG C CG  1 
ATOM   6496  C CD  . ARG C 1 36  ? 45.752  -22.752 2.345   1.00 24.14  ? 36  ARG C CD  1 
ATOM   6497  N NE  . ARG C 1 36  ? 46.241  -22.446 3.692   1.00 24.79  ? 36  ARG C NE  1 
ATOM   6498  C CZ  . ARG C 1 36  ? 47.340  -22.969 4.233   1.00 25.30  ? 36  ARG C CZ  1 
ATOM   6499  N NH1 . ARG C 1 36  ? 48.106  -23.816 3.569   1.00 19.47  ? 36  ARG C NH1 1 
ATOM   6500  N NH2 . ARG C 1 36  ? 47.660  -22.659 5.482   1.00 26.36  ? 36  ARG C NH2 1 
ATOM   6501  N N   . PHE C 1 37  ? 47.166  -20.500 -1.588  1.00 24.64  ? 37  PHE C N   1 
ATOM   6502  C CA  . PHE C 1 37  ? 48.416  -20.773 -2.287  1.00 27.73  ? 37  PHE C CA  1 
ATOM   6503  C C   . PHE C 1 37  ? 48.790  -19.685 -3.275  1.00 27.12  ? 37  PHE C C   1 
ATOM   6504  O O   . PHE C 1 37  ? 49.908  -19.707 -3.798  1.00 29.99  ? 37  PHE C O   1 
ATOM   6505  C CB  . PHE C 1 37  ? 48.327  -22.150 -2.944  1.00 21.45  ? 37  PHE C CB  1 
ATOM   6506  C CG  . PHE C 1 37  ? 48.249  -23.249 -1.925  1.00 24.11  ? 37  PHE C CG  1 
ATOM   6507  C CD1 . PHE C 1 37  ? 49.226  -23.349 -0.950  1.00 23.38  ? 37  PHE C CD1 1 
ATOM   6508  C CD2 . PHE C 1 37  ? 47.187  -24.134 -1.890  1.00 27.11  ? 37  PHE C CD2 1 
ATOM   6509  C CE1 . PHE C 1 37  ? 49.166  -24.323 0.020   1.00 23.95  ? 37  PHE C CE1 1 
ATOM   6510  C CE2 . PHE C 1 37  ? 47.123  -25.114 -0.909  1.00 31.00  ? 37  PHE C CE2 1 
ATOM   6511  C CZ  . PHE C 1 37  ? 48.122  -25.197 0.052   1.00 21.29  ? 37  PHE C CZ  1 
ATOM   6512  N N   . LEU C 1 38  ? 47.911  -18.704 -3.483  1.00 25.92  ? 38  LEU C N   1 
ATOM   6513  C CA  . LEU C 1 38  ? 48.242  -17.536 -4.296  1.00 23.19  ? 38  LEU C CA  1 
ATOM   6514  C C   . LEU C 1 38  ? 49.307  -16.666 -3.655  1.00 27.00  ? 38  LEU C C   1 
ATOM   6515  O O   . LEU C 1 38  ? 49.901  -15.840 -4.344  1.00 28.71  ? 38  LEU C O   1 
ATOM   6516  C CB  . LEU C 1 38  ? 46.986  -16.694 -4.537  1.00 32.05  ? 38  LEU C CB  1 
ATOM   6517  C CG  . LEU C 1 38  ? 46.531  -16.530 -5.984  1.00 34.07  ? 38  LEU C CG  1 
ATOM   6518  C CD1 . LEU C 1 38  ? 45.304  -15.684 -6.012  1.00 34.56  ? 38  LEU C CD1 1 
ATOM   6519  C CD2 . LEU C 1 38  ? 47.617  -15.888 -6.819  1.00 31.60  ? 38  LEU C CD2 1 
ATOM   6520  N N   . TRP C 1 39  ? 49.567  -16.824 -2.354  1.00 25.28  ? 39  TRP C N   1 
ATOM   6521  C CA  . TRP C 1 39  ? 50.649  -16.068 -1.738  1.00 25.40  ? 39  TRP C CA  1 
ATOM   6522  C C   . TRP C 1 39  ? 52.028  -16.548 -2.183  1.00 24.42  ? 39  TRP C C   1 
ATOM   6523  O O   . TRP C 1 39  ? 53.028  -15.906 -1.839  1.00 23.49  ? 39  TRP C O   1 
ATOM   6524  C CB  . TRP C 1 39  ? 50.521  -16.130 -0.216  1.00 25.61  ? 39  TRP C CB  1 
ATOM   6525  C CG  . TRP C 1 39  ? 49.365  -15.352 0.304   1.00 23.45  ? 39  TRP C CG  1 
ATOM   6526  C CD1 . TRP C 1 39  ? 48.108  -15.820 0.561   1.00 27.62  ? 39  TRP C CD1 1 
ATOM   6527  C CD2 . TRP C 1 39  ? 49.349  -13.955 0.617   1.00 24.71  ? 39  TRP C CD2 1 
ATOM   6528  N NE1 . TRP C 1 39  ? 47.308  -14.796 1.021   1.00 25.34  ? 39  TRP C NE1 1 
ATOM   6529  C CE2 . TRP C 1 39  ? 48.048  -13.640 1.064   1.00 28.08  ? 39  TRP C CE2 1 
ATOM   6530  C CE3 . TRP C 1 39  ? 50.307  -12.934 0.551   1.00 28.86  ? 39  TRP C CE3 1 
ATOM   6531  C CZ2 . TRP C 1 39  ? 47.678  -12.339 1.446   1.00 26.48  ? 39  TRP C CZ2 1 
ATOM   6532  C CZ3 . TRP C 1 39  ? 49.943  -11.639 0.940   1.00 23.60  ? 39  TRP C CZ3 1 
ATOM   6533  C CH2 . TRP C 1 39  ? 48.643  -11.363 1.392   1.00 24.76  ? 39  TRP C CH2 1 
ATOM   6534  N N   . HIS C 1 40  ? 52.095  -17.650 -2.937  1.00 21.83  ? 40  HIS C N   1 
ATOM   6535  C CA  . HIS C 1 40  ? 53.316  -18.112 -3.592  1.00 26.52  ? 40  HIS C CA  1 
ATOM   6536  C C   . HIS C 1 40  ? 53.587  -17.379 -4.909  1.00 32.45  ? 40  HIS C C   1 
ATOM   6537  O O   . HIS C 1 40  ? 54.728  -17.371 -5.375  1.00 32.30  ? 40  HIS C O   1 
ATOM   6538  C CB  . HIS C 1 40  ? 53.218  -19.617 -3.892  1.00 27.10  ? 40  HIS C CB  1 
ATOM   6539  C CG  . HIS C 1 40  ? 53.445  -20.513 -2.707  1.00 27.28  ? 40  HIS C CG  1 
ATOM   6540  N ND1 . HIS C 1 40  ? 54.651  -20.585 -2.039  1.00 28.23  ? 40  HIS C ND1 1 
ATOM   6541  C CD2 . HIS C 1 40  ? 52.630  -21.415 -2.105  1.00 24.72  ? 40  HIS C CD2 1 
ATOM   6542  C CE1 . HIS C 1 40  ? 54.566  -21.481 -1.073  1.00 21.48  ? 40  HIS C CE1 1 
ATOM   6543  N NE2 . HIS C 1 40  ? 53.350  -22.000 -1.090  1.00 22.47  ? 40  HIS C NE2 1 
ATOM   6544  N N   . ALA C 1 41  ? 52.570  -16.748 -5.502  1.00 31.83  ? 41  ALA C N   1 
ATOM   6545  C CA  . ALA C 1 41  ? 52.652  -16.308 -6.888  1.00 31.76  ? 41  ALA C CA  1 
ATOM   6546  C C   . ALA C 1 41  ? 53.654  -15.174 -7.074  1.00 30.06  ? 41  ALA C C   1 
ATOM   6547  O O   . ALA C 1 41  ? 53.810  -14.302 -6.216  1.00 36.34  ? 41  ALA C O   1 
ATOM   6548  C CB  . ALA C 1 41  ? 51.267  -15.873 -7.389  1.00 32.73  ? 41  ALA C CB  1 
ATOM   6549  N N   . GLU C 1 42  ? 54.370  -15.220 -8.193  1.00 30.38  ? 42  GLU C N   1 
ATOM   6550  C CA  . GLU C 1 42  ? 55.147  -14.097 -8.689  1.00 33.97  ? 42  GLU C CA  1 
ATOM   6551  C C   . GLU C 1 42  ? 54.673  -13.802 -10.105 1.00 35.71  ? 42  GLU C C   1 
ATOM   6552  O O   . GLU C 1 42  ? 53.872  -14.548 -10.675 1.00 34.41  ? 42  GLU C O   1 
ATOM   6553  C CB  . GLU C 1 42  ? 56.658  -14.379 -8.637  1.00 33.86  ? 42  GLU C CB  1 
ATOM   6554  C CG  . GLU C 1 42  ? 57.178  -14.779 -7.241  1.00 33.73  ? 42  GLU C CG  1 
ATOM   6555  C CD  . GLU C 1 42  ? 57.700  -13.582 -6.428  1.00 45.41  ? 42  GLU C CD  1 
ATOM   6556  O OE1 . GLU C 1 42  ? 57.480  -12.420 -6.856  1.00 45.55  ? 42  GLU C OE1 1 
ATOM   6557  O OE2 . GLU C 1 42  ? 58.318  -13.799 -5.358  1.00 45.87  ? 42  GLU C OE2 1 
ATOM   6558  N N   . ASP C 1 43  ? 55.172  -12.707 -10.671 1.00 34.88  ? 43  ASP C N   1 
ATOM   6559  C CA  . ASP C 1 43  ? 54.706  -12.237 -11.973 1.00 34.33  ? 43  ASP C CA  1 
ATOM   6560  C C   . ASP C 1 43  ? 54.627  -13.375 -12.983 1.00 37.70  ? 43  ASP C C   1 
ATOM   6561  O O   . ASP C 1 43  ? 55.561  -14.167 -13.122 1.00 38.41  ? 43  ASP C O   1 
ATOM   6562  C CB  . ASP C 1 43  ? 55.640  -11.145 -12.494 1.00 38.19  ? 43  ASP C CB  1 
ATOM   6563  C CG  . ASP C 1 43  ? 55.266  -9.752  -11.996 1.00 43.13  ? 43  ASP C CG  1 
ATOM   6564  O OD1 . ASP C 1 43  ? 54.617  -9.622  -10.932 1.00 38.99  ? 43  ASP C OD1 1 
ATOM   6565  O OD2 . ASP C 1 43  ? 55.640  -8.772  -12.675 1.00 53.50  ? 43  ASP C OD2 1 
ATOM   6566  N N   . GLY C 1 44  ? 53.494  -13.473 -13.662 1.00 33.11  ? 44  GLY C N   1 
ATOM   6567  C CA  . GLY C 1 44  ? 53.346  -14.449 -14.712 1.00 37.99  ? 44  GLY C CA  1 
ATOM   6568  C C   . GLY C 1 44  ? 52.980  -15.846 -14.270 1.00 38.19  ? 44  GLY C C   1 
ATOM   6569  O O   . GLY C 1 44  ? 52.772  -16.709 -15.130 1.00 45.76  ? 44  GLY C O   1 
ATOM   6570  N N   . ASP C 1 45  ? 52.865  -16.099 -12.970 1.00 39.76  ? 45  ASP C N   1 
ATOM   6571  C CA  . ASP C 1 45  ? 52.603  -17.454 -12.500 1.00 35.64  ? 45  ASP C CA  1 
ATOM   6572  C C   . ASP C 1 45  ? 51.174  -17.891 -12.813 1.00 34.82  ? 45  ASP C C   1 
ATOM   6573  O O   . ASP C 1 45  ? 50.268  -17.084 -13.028 1.00 34.70  ? 45  ASP C O   1 
ATOM   6574  C CB  . ASP C 1 45  ? 52.832  -17.573 -10.993 1.00 31.43  ? 45  ASP C CB  1 
ATOM   6575  C CG  . ASP C 1 45  ? 54.303  -17.634 -10.620 1.00 37.26  ? 45  ASP C CG  1 
ATOM   6576  O OD1 . ASP C 1 45  ? 55.154  -17.423 -11.515 1.00 36.98  ? 45  ASP C OD1 1 
ATOM   6577  O OD2 . ASP C 1 45  ? 54.601  -17.894 -9.424  1.00 36.76  ? 45  ASP C OD2 1 
ATOM   6578  N N   . VAL C 1 46  ? 50.981  -19.203 -12.800 1.00 37.91  ? 46  VAL C N   1 
ATOM   6579  C CA  . VAL C 1 46  ? 49.676  -19.822 -12.964 1.00 28.09  ? 46  VAL C CA  1 
ATOM   6580  C C   . VAL C 1 46  ? 49.394  -20.620 -11.702 1.00 32.41  ? 46  VAL C C   1 
ATOM   6581  O O   . VAL C 1 46  ? 50.197  -21.476 -11.314 1.00 32.16  ? 46  VAL C O   1 
ATOM   6582  C CB  . VAL C 1 46  ? 49.635  -20.733 -14.203 1.00 33.22  ? 46  VAL C CB  1 
ATOM   6583  C CG1 . VAL C 1 46  ? 48.454  -21.668 -14.131 1.00 33.06  ? 46  VAL C CG1 1 
ATOM   6584  C CG2 . VAL C 1 46  ? 49.584  -19.914 -15.467 1.00 37.62  ? 46  VAL C CG2 1 
ATOM   6585  N N   . LEU C 1 47  ? 48.260  -20.349 -11.064 1.00 36.79  ? 47  LEU C N   1 
ATOM   6586  C CA  . LEU C 1 47  ? 47.759  -21.170 -9.967  1.00 35.49  ? 47  LEU C CA  1 
ATOM   6587  C C   . LEU C 1 47  ? 46.644  -22.067 -10.481 1.00 36.42  ? 47  LEU C C   1 
ATOM   6588  O O   . LEU C 1 47  ? 45.712  -21.586 -11.129 1.00 37.16  ? 47  LEU C O   1 
ATOM   6589  C CB  . LEU C 1 47  ? 47.230  -20.294 -8.831  1.00 30.92  ? 47  LEU C CB  1 
ATOM   6590  C CG  . LEU C 1 47  ? 46.366  -20.998 -7.795  1.00 27.94  ? 47  LEU C CG  1 
ATOM   6591  C CD1 . LEU C 1 47  ? 47.169  -22.041 -7.042  1.00 33.14  ? 47  LEU C CD1 1 
ATOM   6592  C CD2 . LEU C 1 47  ? 45.818  -19.970 -6.831  1.00 35.44  ? 47  LEU C CD2 1 
ATOM   6593  N N   . VAL C 1 48  ? 46.723  -23.360 -10.188 1.00 31.08  ? 48  VAL C N   1 
ATOM   6594  C CA  . VAL C 1 48  ? 45.612  -24.266 -10.463 1.00 37.71  ? 48  VAL C CA  1 
ATOM   6595  C C   . VAL C 1 48  ? 44.836  -24.429 -9.167  1.00 34.76  ? 48  VAL C C   1 
ATOM   6596  O O   . VAL C 1 48  ? 45.431  -24.662 -8.113  1.00 39.36  ? 48  VAL C O   1 
ATOM   6597  C CB  . VAL C 1 48  ? 46.093  -25.626 -11.006 1.00 39.07  ? 48  VAL C CB  1 
ATOM   6598  C CG1 . VAL C 1 48  ? 44.905  -26.512 -11.335 1.00 36.08  ? 48  VAL C CG1 1 
ATOM   6599  C CG2 . VAL C 1 48  ? 46.947  -25.450 -12.238 1.00 34.59  ? 48  VAL C CG2 1 
ATOM   6600  N N   . ILE C 1 49  ? 43.523  -24.246 -9.217  1.00 33.00  ? 49  ILE C N   1 
ATOM   6601  C CA  . ILE C 1 49  ? 42.724  -24.449 -8.007  1.00 42.01  ? 49  ILE C CA  1 
ATOM   6602  C C   . ILE C 1 49  ? 41.547  -25.361 -8.332  1.00 42.24  ? 49  ILE C C   1 
ATOM   6603  O O   . ILE C 1 49  ? 40.942  -25.235 -9.407  1.00 43.64  ? 49  ILE C O   1 
ATOM   6604  C CB  . ILE C 1 49  ? 42.258  -23.114 -7.396  1.00 40.58  ? 49  ILE C CB  1 
ATOM   6605  C CG1 . ILE C 1 49  ? 41.695  -22.163 -8.444  1.00 42.86  ? 49  ILE C CG1 1 
ATOM   6606  C CG2 . ILE C 1 49  ? 43.380  -22.415 -6.700  1.00 44.14  ? 49  ILE C CG2 1 
ATOM   6607  C CD1 . ILE C 1 49  ? 40.203  -22.271 -8.573  1.00 44.50  ? 49  ILE C CD1 1 
ATOM   6608  N N   . PRO C 1 50  ? 41.212  -26.306 -7.458  1.00 45.33  ? 50  PRO C N   1 
ATOM   6609  C CA  . PRO C 1 50  ? 40.076  -27.194 -7.723  1.00 45.94  ? 50  PRO C CA  1 
ATOM   6610  C C   . PRO C 1 50  ? 38.756  -26.613 -7.254  1.00 48.00  ? 50  PRO C C   1 
ATOM   6611  O O   . PRO C 1 50  ? 37.688  -27.022 -7.721  1.00 52.62  ? 50  PRO C O   1 
ATOM   6612  C CB  . PRO C 1 50  ? 40.440  -28.447 -6.922  1.00 44.56  ? 50  PRO C CB  1 
ATOM   6613  C CG  . PRO C 1 50  ? 41.131  -27.889 -5.734  1.00 41.66  ? 50  PRO C CG  1 
ATOM   6614  C CD  . PRO C 1 50  ? 41.947  -26.718 -6.252  1.00 40.81  ? 50  PRO C CD  1 
ATOM   6615  N N   . ASP C 1 51  ? 38.814  -25.680 -6.308  1.00 47.90  ? 51  ASP C N   1 
ATOM   6616  C CA  . ASP C 1 51  ? 37.601  -25.138 -5.710  1.00 49.69  ? 51  ASP C CA  1 
ATOM   6617  C C   . ASP C 1 51  ? 37.225  -23.829 -6.389  1.00 48.12  ? 51  ASP C C   1 
ATOM   6618  O O   . ASP C 1 51  ? 37.297  -23.721 -7.617  1.00 52.44  ? 51  ASP C O   1 
ATOM   6619  C CB  . ASP C 1 51  ? 37.791  -24.951 -4.206  1.00 46.34  ? 51  ASP C CB  1 
ATOM   6620  C CG  . ASP C 1 51  ? 39.221  -24.628 -3.840  1.00 43.69  ? 51  ASP C CG  1 
ATOM   6621  O OD1 . ASP C 1 51  ? 39.996  -24.254 -4.748  1.00 45.53  ? 51  ASP C OD1 1 
ATOM   6622  O OD2 . ASP C 1 51  ? 39.578  -24.752 -2.650  1.00 40.54  ? 51  ASP C OD2 1 
ATOM   6623  N N   . THR C 1 52  ? 36.803  -22.835 -5.617  1.00 48.46  ? 52  THR C N   1 
ATOM   6624  C CA  . THR C 1 52  ? 36.512  -21.526 -6.184  1.00 51.13  ? 52  THR C CA  1 
ATOM   6625  C C   . THR C 1 52  ? 36.946  -20.455 -5.204  1.00 49.43  ? 52  THR C C   1 
ATOM   6626  O O   . THR C 1 52  ? 36.592  -20.502 -4.021  1.00 43.41  ? 52  THR C O   1 
ATOM   6627  C CB  . THR C 1 52  ? 35.029  -21.354 -6.520  1.00 49.60  ? 52  THR C CB  1 
ATOM   6628  O OG1 . THR C 1 52  ? 34.559  -22.524 -7.193  1.00 60.34  ? 52  THR C OG1 1 
ATOM   6629  C CG2 . THR C 1 52  ? 34.836  -20.146 -7.441  1.00 48.91  ? 52  THR C CG2 1 
ATOM   6630  N N   . VAL C 1 53  ? 37.694  -19.500 -5.710  1.00 43.41  ? 53  VAL C N   1 
ATOM   6631  C CA  . VAL C 1 53  ? 38.252  -18.420 -4.918  1.00 43.74  ? 53  VAL C CA  1 
ATOM   6632  C C   . VAL C 1 53  ? 37.404  -17.178 -5.127  1.00 45.82  ? 53  VAL C C   1 
ATOM   6633  O O   . VAL C 1 53  ? 36.801  -16.985 -6.189  1.00 46.26  ? 53  VAL C O   1 
ATOM   6634  C CB  . VAL C 1 53  ? 39.726  -18.183 -5.313  1.00 47.25  ? 53  VAL C CB  1 
ATOM   6635  C CG1 . VAL C 1 53  ? 39.829  -17.763 -6.778  1.00 53.15  ? 53  VAL C CG1 1 
ATOM   6636  C CG2 . VAL C 1 53  ? 40.339  -17.139 -4.442  1.00 45.77  ? 53  VAL C CG2 1 
ATOM   6637  N N   . ASP C 1 54  ? 37.324  -16.346 -4.093  1.00 45.97  ? 54  ASP C N   1 
ATOM   6638  C CA  . ASP C 1 54  ? 36.763  -15.016 -4.259  1.00 42.95  ? 54  ASP C CA  1 
ATOM   6639  C C   . ASP C 1 54  ? 37.363  -14.358 -5.499  1.00 42.99  ? 54  ASP C C   1 
ATOM   6640  O O   . ASP C 1 54  ? 38.594  -14.330 -5.650  1.00 37.81  ? 54  ASP C O   1 
ATOM   6641  C CB  . ASP C 1 54  ? 37.046  -14.152 -3.032  1.00 45.27  ? 54  ASP C CB  1 
ATOM   6642  C CG  . ASP C 1 54  ? 36.230  -12.867 -3.018  1.00 41.93  ? 54  ASP C CG  1 
ATOM   6643  O OD1 . ASP C 1 54  ? 36.350  -12.075 -3.983  1.00 40.50  ? 54  ASP C OD1 1 
ATOM   6644  O OD2 . ASP C 1 54  ? 35.482  -12.657 -2.034  1.00 39.07  ? 54  ASP C OD2 1 
ATOM   6645  N N   . PRO C 1 55  ? 36.541  -13.838 -6.406  1.00 43.60  ? 55  PRO C N   1 
ATOM   6646  C CA  . PRO C 1 55  ? 37.095  -13.236 -7.627  1.00 39.82  ? 55  PRO C CA  1 
ATOM   6647  C C   . PRO C 1 55  ? 38.046  -12.078 -7.351  1.00 38.73  ? 55  PRO C C   1 
ATOM   6648  O O   . PRO C 1 55  ? 38.903  -11.786 -8.195  1.00 36.10  ? 55  PRO C O   1 
ATOM   6649  C CB  . PRO C 1 55  ? 35.843  -12.778 -8.385  1.00 35.75  ? 55  PRO C CB  1 
ATOM   6650  C CG  . PRO C 1 55  ? 34.733  -13.632 -7.835  1.00 43.43  ? 55  PRO C CG  1 
ATOM   6651  C CD  . PRO C 1 55  ? 35.070  -13.880 -6.408  1.00 43.17  ? 55  PRO C CD  1 
ATOM   6652  N N   . ASP C 1 56  ? 37.932  -11.425 -6.191  1.00 37.62  ? 56  ASP C N   1 
ATOM   6653  C CA  . ASP C 1 56  ? 38.785  -10.304 -5.832  1.00 34.56  ? 56  ASP C CA  1 
ATOM   6654  C C   . ASP C 1 56  ? 40.084  -10.734 -5.186  1.00 36.78  ? 56  ASP C C   1 
ATOM   6655  O O   . ASP C 1 56  ? 40.897  -9.873  -4.821  1.00 33.66  ? 56  ASP C O   1 
ATOM   6656  C CB  . ASP C 1 56  ? 38.042  -9.372  -4.883  1.00 39.65  ? 56  ASP C CB  1 
ATOM   6657  C CG  . ASP C 1 56  ? 37.331  -8.272  -5.623  1.00 40.03  ? 56  ASP C CG  1 
ATOM   6658  O OD1 . ASP C 1 56  ? 37.430  -8.276  -6.868  1.00 45.94  ? 56  ASP C OD1 1 
ATOM   6659  O OD2 . ASP C 1 56  ? 36.690  -7.427  -4.986  1.00 32.51  ? 56  ASP C OD2 1 
ATOM   6660  N N   . PHE C 1 57  ? 40.293  -12.039 -5.029  1.00 30.77  ? 57  PHE C N   1 
ATOM   6661  C CA  . PHE C 1 57  ? 41.401  -12.487 -4.186  1.00 38.02  ? 57  PHE C CA  1 
ATOM   6662  C C   . PHE C 1 57  ? 42.750  -12.288 -4.848  1.00 33.56  ? 57  PHE C C   1 
ATOM   6663  O O   . PHE C 1 57  ? 43.636  -11.686 -4.209  1.00 29.55  ? 57  PHE C O   1 
ATOM   6664  C CB  . PHE C 1 57  ? 41.176  -13.935 -3.764  1.00 37.81  ? 57  PHE C CB  1 
ATOM   6665  C CG  . PHE C 1 57  ? 41.891  -14.296 -2.519  1.00 42.63  ? 57  PHE C CG  1 
ATOM   6666  C CD1 . PHE C 1 57  ? 41.422  -13.858 -1.297  1.00 39.08  ? 57  PHE C CD1 1 
ATOM   6667  C CD2 . PHE C 1 57  ? 43.033  -15.079 -2.562  1.00 39.63  ? 57  PHE C CD2 1 
ATOM   6668  C CE1 . PHE C 1 57  ? 42.079  -14.181 -0.132  1.00 32.29  ? 57  PHE C CE1 1 
ATOM   6669  C CE2 . PHE C 1 57  ? 43.683  -15.411 -1.403  1.00 38.80  ? 57  PHE C CE2 1 
ATOM   6670  C CZ  . PHE C 1 57  ? 43.202  -14.950 -0.179  1.00 35.60  ? 57  PHE C CZ  1 
ATOM   6671  N N   . PRO C 1 58  ? 43.007  -12.761 -6.101  1.00 33.54  ? 58  PRO C N   1 
ATOM   6672  C CA  . PRO C 1 58  ? 44.301  -12.479 -6.732  1.00 25.81  ? 58  PRO C CA  1 
ATOM   6673  C C   . PRO C 1 58  ? 44.718  -11.041 -6.524  1.00 27.49  ? 58  PRO C C   1 
ATOM   6674  O O   . PRO C 1 58  ? 45.810  -10.772 -6.012  1.00 27.27  ? 58  PRO C O   1 
ATOM   6675  C CB  . PRO C 1 58  ? 44.052  -12.768 -8.212  1.00 29.35  ? 58  PRO C CB  1 
ATOM   6676  C CG  . PRO C 1 58  ? 42.958  -13.764 -8.237  1.00 33.99  ? 58  PRO C CG  1 
ATOM   6677  C CD  . PRO C 1 58  ? 42.156  -13.621 -6.955  1.00 33.45  ? 58  PRO C CD  1 
ATOM   6678  N N   . GLY C 1 59  ? 43.792  -10.131 -6.853  1.00 29.45  ? 59  GLY C N   1 
ATOM   6679  C CA  . GLY C 1 59  ? 44.070  -8.709  -6.759  1.00 30.70  ? 59  GLY C CA  1 
ATOM   6680  C C   . GLY C 1 59  ? 44.422  -8.259  -5.354  1.00 24.66  ? 59  GLY C C   1 
ATOM   6681  O O   . GLY C 1 59  ? 45.325  -7.441  -5.163  1.00 30.56  ? 59  GLY C O   1 
ATOM   6682  N N   . TYR C 1 60  ? 43.726  -8.786  -4.355  1.00 21.40  ? 60  TYR C N   1 
ATOM   6683  C CA  . TYR C 1 60  ? 44.033  -8.396  -2.988  1.00 22.86  ? 60  TYR C CA  1 
ATOM   6684  C C   . TYR C 1 60  ? 45.414  -8.882  -2.576  1.00 25.77  ? 60  TYR C C   1 
ATOM   6685  O O   . TYR C 1 60  ? 46.116  -8.196  -1.827  1.00 25.21  ? 60  TYR C O   1 
ATOM   6686  C CB  . TYR C 1 60  ? 42.977  -8.937  -2.049  1.00 19.74  ? 60  TYR C CB  1 
ATOM   6687  C CG  . TYR C 1 60  ? 43.474  -9.132  -0.639  1.00 24.45  ? 60  TYR C CG  1 
ATOM   6688  C CD1 . TYR C 1 60  ? 43.758  -8.048  0.164   1.00 23.49  ? 60  TYR C CD1 1 
ATOM   6689  C CD2 . TYR C 1 60  ? 43.668  -10.401 -0.118  1.00 22.67  ? 60  TYR C CD2 1 
ATOM   6690  C CE1 . TYR C 1 60  ? 44.199  -8.209  1.443   1.00 26.24  ? 60  TYR C CE1 1 
ATOM   6691  C CE2 . TYR C 1 60  ? 44.118  -10.568 1.158   1.00 23.35  ? 60  TYR C CE2 1 
ATOM   6692  C CZ  . TYR C 1 60  ? 44.384  -9.462  1.938   1.00 23.80  ? 60  TYR C CZ  1 
ATOM   6693  O OH  . TYR C 1 60  ? 44.839  -9.590  3.223   1.00 23.95  ? 60  TYR C OH  1 
ATOM   6694  N N   . VAL C 1 61  ? 45.806  -10.069 -3.046  1.00 25.94  ? 61  VAL C N   1 
ATOM   6695  C CA  . VAL C 1 61  ? 47.108  -10.648 -2.710  1.00 28.48  ? 61  VAL C CA  1 
ATOM   6696  C C   . VAL C 1 61  ? 48.209  -9.898  -3.434  1.00 27.10  ? 61  VAL C C   1 
ATOM   6697  O O   . VAL C 1 61  ? 49.266  -9.601  -2.856  1.00 24.75  ? 61  VAL C O   1 
ATOM   6698  C CB  . VAL C 1 61  ? 47.135  -12.157 -3.064  1.00 28.46  ? 61  VAL C CB  1 
ATOM   6699  C CG1 . VAL C 1 61  ? 48.491  -12.770 -2.791  1.00 20.76  ? 61  VAL C CG1 1 
ATOM   6700  C CG2 . VAL C 1 61  ? 46.049  -12.920 -2.329  1.00 24.72  ? 61  VAL C CG2 1 
ATOM   6701  N N   . ALA C 1 62  ? 47.968  -9.553  -4.705  1.00 24.13  ? 62  ALA C N   1 
ATOM   6702  C CA  . ALA C 1 62  ? 48.990  -8.846  -5.474  1.00 27.32  ? 62  ALA C CA  1 
ATOM   6703  C C   . ALA C 1 62  ? 49.230  -7.422  -4.954  1.00 30.28  ? 62  ALA C C   1 
ATOM   6704  O O   . ALA C 1 62  ? 50.374  -6.951  -4.944  1.00 33.46  ? 62  ALA C O   1 
ATOM   6705  C CB  . ALA C 1 62  ? 48.623  -8.843  -6.953  1.00 29.80  ? 62  ALA C CB  1 
ATOM   6706  N N   . ASP C 1 63  ? 48.183  -6.716  -4.511  1.00 31.99  ? 63  ASP C N   1 
ATOM   6707  C CA  . ASP C 1 63  ? 48.402  -5.410  -3.884  1.00 31.41  ? 63  ASP C CA  1 
ATOM   6708  C C   . ASP C 1 63  ? 49.261  -5.542  -2.642  1.00 33.80  ? 63  ASP C C   1 
ATOM   6709  O O   . ASP C 1 63  ? 50.134  -4.708  -2.382  1.00 32.90  ? 63  ASP C O   1 
ATOM   6710  C CB  . ASP C 1 63  ? 47.081  -4.762  -3.460  1.00 34.42  ? 63  ASP C CB  1 
ATOM   6711  C CG  . ASP C 1 63  ? 46.127  -4.580  -4.596  1.00 36.56  ? 63  ASP C CG  1 
ATOM   6712  O OD1 . ASP C 1 63  ? 46.549  -4.799  -5.752  1.00 41.72  ? 63  ASP C OD1 1 
ATOM   6713  O OD2 . ASP C 1 63  ? 44.956  -4.228  -4.320  1.00 32.60  ? 63  ASP C OD2 1 
ATOM   6714  N N   . THR C 1 64  ? 48.958  -6.542  -1.817  1.00 33.49  ? 64  THR C N   1 
ATOM   6715  C CA  . THR C 1 64  ? 49.645  -6.702  -0.546  1.00 30.65  ? 64  THR C CA  1 
ATOM   6716  C C   . THR C 1 64  ? 51.109  -7.085  -0.756  1.00 31.46  ? 64  THR C C   1 
ATOM   6717  O O   . THR C 1 64  ? 51.998  -6.507  -0.119  1.00 32.13  ? 64  THR C O   1 
ATOM   6718  C CB  . THR C 1 64  ? 48.894  -7.739  0.279   1.00 28.67  ? 64  THR C CB  1 
ATOM   6719  O OG1 . THR C 1 64  ? 47.504  -7.377  0.284   1.00 27.84  ? 64  THR C OG1 1 
ATOM   6720  C CG2 . THR C 1 64  ? 49.426  -7.818  1.707   1.00 24.94  ? 64  THR C CG2 1 
ATOM   6721  N N   . LEU C 1 65  ? 51.375  -8.025  -1.678  1.00 28.90  ? 65  LEU C N   1 
ATOM   6722  C CA  . LEU C 1 65  ? 52.726  -8.448  -2.047  1.00 26.72  ? 65  LEU C CA  1 
ATOM   6723  C C   . LEU C 1 65  ? 53.449  -7.461  -2.960  1.00 35.17  ? 65  LEU C C   1 
ATOM   6724  O O   . LEU C 1 65  ? 54.679  -7.503  -3.037  1.00 35.14  ? 65  LEU C O   1 
ATOM   6725  C CB  . LEU C 1 65  ? 52.668  -9.792  -2.764  1.00 29.00  ? 65  LEU C CB  1 
ATOM   6726  C CG  . LEU C 1 65  ? 52.168  -11.000 -1.972  1.00 31.74  ? 65  LEU C CG  1 
ATOM   6727  C CD1 . LEU C 1 65  ? 52.029  -12.198 -2.877  1.00 29.85  ? 65  LEU C CD1 1 
ATOM   6728  C CD2 . LEU C 1 65  ? 53.129  -11.322 -0.809  1.00 31.65  ? 65  LEU C CD2 1 
ATOM   6729  N N   . GLY C 1 66  ? 52.730  -6.598  -3.680  1.00 35.97  ? 66  GLY C N   1 
ATOM   6730  C CA  . GLY C 1 66  ? 53.396  -5.634  -4.537  1.00 28.42  ? 66  GLY C CA  1 
ATOM   6731  C C   . GLY C 1 66  ? 53.813  -6.167  -5.889  1.00 36.48  ? 66  GLY C C   1 
ATOM   6732  O O   . GLY C 1 66  ? 54.802  -5.690  -6.457  1.00 39.39  ? 66  GLY C O   1 
ATOM   6733  N N   . ILE C 1 67  ? 53.093  -7.147  -6.424  1.00 29.70  ? 67  ILE C N   1 
ATOM   6734  C CA  . ILE C 1 67  ? 53.392  -7.714  -7.731  1.00 38.84  ? 67  ILE C CA  1 
ATOM   6735  C C   . ILE C 1 67  ? 52.265  -7.361  -8.695  1.00 38.91  ? 67  ILE C C   1 
ATOM   6736  O O   . ILE C 1 67  ? 51.185  -6.929  -8.294  1.00 34.86  ? 67  ILE C O   1 
ATOM   6737  C CB  . ILE C 1 67  ? 53.591  -9.244  -7.660  1.00 37.28  ? 67  ILE C CB  1 
ATOM   6738  C CG1 . ILE C 1 67  ? 52.263  -9.941  -7.371  1.00 34.79  ? 67  ILE C CG1 1 
ATOM   6739  C CG2 . ILE C 1 67  ? 54.605  -9.592  -6.599  1.00 32.54  ? 67  ILE C CG2 1 
ATOM   6740  C CD1 . ILE C 1 67  ? 52.399  -11.447 -7.212  1.00 35.03  ? 67  ILE C CD1 1 
ATOM   6741  N N   . ASP C 1 68  ? 52.521  -7.577  -9.985  1.00 40.18  ? 68  ASP C N   1 
ATOM   6742  C CA  . ASP C 1 68  ? 51.572  -7.249  -11.049 1.00 43.99  ? 68  ASP C CA  1 
ATOM   6743  C C   . ASP C 1 68  ? 50.504  -8.333  -11.150 1.00 44.17  ? 68  ASP C C   1 
ATOM   6744  O O   . ASP C 1 68  ? 50.648  -9.318  -11.874 1.00 43.36  ? 68  ASP C O   1 
ATOM   6745  C CB  . ASP C 1 68  ? 52.291  -7.077  -12.381 1.00 42.72  ? 68  ASP C CB  1 
ATOM   6746  C CG  . ASP C 1 68  ? 51.324  -6.827  -13.524 1.00 52.57  ? 68  ASP C CG  1 
ATOM   6747  O OD1 . ASP C 1 68  ? 50.257  -6.225  -13.261 1.00 50.15  ? 68  ASP C OD1 1 
ATOM   6748  O OD2 . ASP C 1 68  ? 51.613  -7.251  -14.670 1.00 49.01  ? 68  ASP C OD2 1 
ATOM   6749  N N   . GLY C 1 69  ? 49.387  -8.116  -10.460 1.00 43.95  ? 69  GLY C N   1 
ATOM   6750  C CA  . GLY C 1 69  ? 48.315  -9.096  -10.433 1.00 42.90  ? 69  GLY C CA  1 
ATOM   6751  C C   . GLY C 1 69  ? 47.661  -9.376  -11.773 1.00 49.34  ? 69  GLY C C   1 
ATOM   6752  O O   . GLY C 1 69  ? 46.992  -10.407 -11.909 1.00 49.16  ? 69  GLY C O   1 
ATOM   6753  N N   . THR C 1 70  ? 47.821  -8.500  -12.763 1.00 50.56  ? 70  THR C N   1 
ATOM   6754  C CA  . THR C 1 70  ? 47.220  -8.816  -14.052 1.00 48.13  ? 70  THR C CA  1 
ATOM   6755  C C   . THR C 1 70  ? 47.977  -9.912  -14.790 1.00 45.82  ? 70  THR C C   1 
ATOM   6756  O O   . THR C 1 70  ? 47.470  -10.424 -15.797 1.00 43.72  ? 70  THR C O   1 
ATOM   6757  C CB  . THR C 1 70  ? 47.126  -7.567  -14.933 1.00 40.90  ? 70  THR C CB  1 
ATOM   6758  O OG1 . THR C 1 70  ? 48.387  -7.328  -15.569 1.00 47.92  ? 70  THR C OG1 1 
ATOM   6759  C CG2 . THR C 1 70  ? 46.724  -6.349  -14.100 1.00 48.46  ? 70  THR C CG2 1 
ATOM   6760  N N   . SER C 1 71  ? 49.160  -10.296 -14.304 1.00 44.43  ? 71  SER C N   1 
ATOM   6761  C CA  . SER C 1 71  ? 49.940  -11.353 -14.933 1.00 46.61  ? 71  SER C CA  1 
ATOM   6762  C C   . SER C 1 71  ? 49.807  -12.702 -14.236 1.00 47.67  ? 71  SER C C   1 
ATOM   6763  O O   . SER C 1 71  ? 50.126  -13.731 -14.846 1.00 47.61  ? 71  SER C O   1 
ATOM   6764  C CB  . SER C 1 71  ? 51.420  -10.949 -15.000 1.00 45.31  ? 71  SER C CB  1 
ATOM   6765  O OG  . SER C 1 71  ? 52.002  -10.904 -13.706 1.00 45.19  ? 71  SER C OG  1 
ATOM   6766  N N   . VAL C 1 72  ? 49.350  -12.731 -12.985 1.00 48.38  ? 72  VAL C N   1 
ATOM   6767  C CA  . VAL C 1 72  ? 49.101  -13.998 -12.309 1.00 44.85  ? 72  VAL C CA  1 
ATOM   6768  C C   . VAL C 1 72  ? 47.790  -14.569 -12.826 1.00 43.77  ? 72  VAL C C   1 
ATOM   6769  O O   . VAL C 1 72  ? 46.762  -13.883 -12.853 1.00 42.65  ? 72  VAL C O   1 
ATOM   6770  C CB  . VAL C 1 72  ? 49.086  -13.824 -10.779 1.00 41.50  ? 72  VAL C CB  1 
ATOM   6771  C CG1 . VAL C 1 72  ? 48.257  -12.649 -10.376 1.00 49.57  ? 72  VAL C CG1 1 
ATOM   6772  C CG2 . VAL C 1 72  ? 48.548  -15.067 -10.109 1.00 36.82  ? 72  VAL C CG2 1 
ATOM   6773  N N   . HIS C 1 73  ? 47.825  -15.827 -13.250 1.00 40.08  ? 73  HIS C N   1 
ATOM   6774  C CA  . HIS C 1 73  ? 46.687  -16.459 -13.890 1.00 35.09  ? 73  HIS C CA  1 
ATOM   6775  C C   . HIS C 1 73  ? 46.152  -17.562 -12.997 1.00 39.20  ? 73  HIS C C   1 
ATOM   6776  O O   . HIS C 1 73  ? 46.912  -18.239 -12.297 1.00 38.20  ? 73  HIS C O   1 
ATOM   6777  C CB  . HIS C 1 73  ? 47.074  -17.006 -15.263 1.00 38.83  ? 73  HIS C CB  1 
ATOM   6778  C CG  . HIS C 1 73  ? 47.552  -15.949 -16.216 1.00 44.04  ? 73  HIS C CG  1 
ATOM   6779  N ND1 . HIS C 1 73  ? 48.886  -15.627 -16.367 1.00 44.26  ? 73  HIS C ND1 1 
ATOM   6780  C CD2 . HIS C 1 73  ? 46.872  -15.134 -17.058 1.00 44.98  ? 73  HIS C CD2 1 
ATOM   6781  C CE1 . HIS C 1 73  ? 49.005  -14.667 -17.268 1.00 46.17  ? 73  HIS C CE1 1 
ATOM   6782  N NE2 . HIS C 1 73  ? 47.799  -14.352 -17.704 1.00 49.85  ? 73  HIS C NE2 1 
ATOM   6783  N N   . VAL C 1 74  ? 44.836  -17.709 -12.995 1.00 35.47  ? 74  VAL C N   1 
ATOM   6784  C CA  . VAL C 1 74  ? 44.160  -18.730 -12.220 1.00 34.80  ? 74  VAL C CA  1 
ATOM   6785  C C   . VAL C 1 74  ? 43.436  -19.615 -13.211 1.00 42.07  ? 74  VAL C C   1 
ATOM   6786  O O   . VAL C 1 74  ? 42.620  -19.128 -14.004 1.00 39.60  ? 74  VAL C O   1 
ATOM   6787  C CB  . VAL C 1 74  ? 43.177  -18.128 -11.210 1.00 36.53  ? 74  VAL C CB  1 
ATOM   6788  C CG1 . VAL C 1 74  ? 42.513  -19.221 -10.428 1.00 41.72  ? 74  VAL C CG1 1 
ATOM   6789  C CG2 . VAL C 1 74  ? 43.886  -17.149 -10.288 1.00 34.29  ? 74  VAL C CG2 1 
ATOM   6790  N N   . GLU C 1 75  ? 43.743  -20.905 -13.180 1.00 39.73  ? 75  GLU C N   1 
ATOM   6791  C CA  . GLU C 1 75  ? 43.044  -21.899 -13.977 1.00 37.91  ? 75  GLU C CA  1 
ATOM   6792  C C   . GLU C 1 75  ? 42.221  -22.776 -13.049 1.00 37.66  ? 75  GLU C C   1 
ATOM   6793  O O   . GLU C 1 75  ? 42.768  -23.412 -12.145 1.00 37.43  ? 75  GLU C O   1 
ATOM   6794  C CB  . GLU C 1 75  ? 44.027  -22.725 -14.804 1.00 38.17  ? 75  GLU C CB  1 
ATOM   6795  C CG  . GLU C 1 75  ? 44.946  -21.854 -15.652 1.00 42.89  ? 75  GLU C CG  1 
ATOM   6796  C CD  . GLU C 1 75  ? 44.295  -21.494 -16.976 1.00 41.78  ? 75  GLU C CD  1 
ATOM   6797  O OE1 . GLU C 1 75  ? 43.174  -21.988 -17.220 1.00 40.38  ? 75  GLU C OE1 1 
ATOM   6798  O OE2 . GLU C 1 75  ? 44.888  -20.716 -17.755 1.00 43.58  ? 75  GLU C OE2 1 
ATOM   6799  N N   . ARG C 1 76  ? 40.914  -22.804 -13.276 1.00 39.72  ? 76  ARG C N   1 
ATOM   6800  C CA  . ARG C 1 76  ? 39.993  -23.564 -12.445 1.00 44.76  ? 76  ARG C CA  1 
ATOM   6801  C C   . ARG C 1 76  ? 39.857  -24.990 -12.963 1.00 50.65  ? 76  ARG C C   1 
ATOM   6802  O O   . ARG C 1 76  ? 39.889  -25.237 -14.172 1.00 47.76  ? 76  ARG C O   1 
ATOM   6803  C CB  . ARG C 1 76  ? 38.622  -22.877 -12.396 1.00 43.96  ? 76  ARG C CB  1 
ATOM   6804  C CG  . ARG C 1 76  ? 38.577  -21.704 -11.445 1.00 48.45  ? 76  ARG C CG  1 
ATOM   6805  C CD  . ARG C 1 76  ? 37.726  -20.541 -11.906 1.00 51.20  ? 76  ARG C CD  1 
ATOM   6806  N NE  . ARG C 1 76  ? 37.794  -19.454 -10.934 1.00 54.46  ? 76  ARG C NE  1 
ATOM   6807  C CZ  . ARG C 1 76  ? 38.269  -18.242 -11.193 1.00 52.89  ? 76  ARG C CZ  1 
ATOM   6808  N NH1 . ARG C 1 76  ? 38.740  -17.924 -12.388 1.00 58.36  ? 76  ARG C NH1 1 
ATOM   6809  N NH2 . ARG C 1 76  ? 38.291  -17.331 -10.222 1.00 50.95  ? 76  ARG C NH2 1 
ATOM   6810  N N   . THR C 1 77  ? 39.748  -25.934 -12.039 1.00 48.27  ? 77  THR C N   1 
ATOM   6811  C CA  . THR C 1 77  ? 39.314  -27.277 -12.374 1.00 49.72  ? 77  THR C CA  1 
ATOM   6812  C C   . THR C 1 77  ? 38.014  -27.553 -11.632 1.00 48.61  ? 77  THR C C   1 
ATOM   6813  O O   . THR C 1 77  ? 37.646  -26.841 -10.694 1.00 52.15  ? 77  THR C O   1 
ATOM   6814  C CB  . THR C 1 77  ? 40.388  -28.328 -12.034 1.00 48.12  ? 77  THR C CB  1 
ATOM   6815  O OG1 . THR C 1 77  ? 40.583  -28.398 -10.616 1.00 44.14  ? 77  THR C OG1 1 
ATOM   6816  C CG2 . THR C 1 77  ? 41.707  -27.981 -12.707 1.00 43.77  ? 77  THR C CG2 1 
ATOM   6817  N N   . GLN C 1 78  ? 37.298  -28.577 -12.075 1.00 48.37  ? 78  GLN C N   1 
ATOM   6818  C CA  . GLN C 1 78  ? 36.086  -28.947 -11.353 1.00 53.22  ? 78  GLN C CA  1 
ATOM   6819  C C   . GLN C 1 78  ? 36.399  -29.836 -10.153 1.00 57.12  ? 78  GLN C C   1 
ATOM   6820  O O   . GLN C 1 78  ? 35.795  -29.674 -9.085  1.00 59.25  ? 78  GLN C O   1 
ATOM   6821  C CB  . GLN C 1 78  ? 35.095  -29.643 -12.287 1.00 55.84  ? 78  GLN C CB  1 
ATOM   6822  C CG  . GLN C 1 78  ? 35.662  -30.777 -13.157 1.00 61.99  ? 78  GLN C CG  1 
ATOM   6823  C CD  . GLN C 1 78  ? 36.538  -30.288 -14.304 1.00 59.40  ? 78  GLN C CD  1 
ATOM   6824  O OE1 . GLN C 1 78  ? 36.126  -29.435 -15.097 1.00 62.94  ? 78  GLN C OE1 1 
ATOM   6825  N NE2 . GLN C 1 78  ? 37.747  -30.840 -14.405 1.00 57.44  ? 78  GLN C NE2 1 
ATOM   6826  N N   . THR C 1 79  ? 37.354  -30.750 -10.304 1.00 57.54  ? 79  THR C N   1 
ATOM   6827  C CA  . THR C 1 79  ? 37.652  -31.830 -9.373  1.00 54.51  ? 79  THR C CA  1 
ATOM   6828  C C   . THR C 1 79  ? 38.932  -31.590 -8.595  1.00 50.80  ? 79  THR C C   1 
ATOM   6829  O O   . THR C 1 79  ? 39.747  -30.729 -8.947  1.00 51.53  ? 79  THR C O   1 
ATOM   6830  C CB  . THR C 1 79  ? 37.789  -33.163 -10.125 1.00 56.54  ? 79  THR C CB  1 
ATOM   6831  O OG1 . THR C 1 79  ? 38.349  -32.940 -11.434 1.00 50.89  ? 79  THR C OG1 1 
ATOM   6832  C CG2 . THR C 1 79  ? 36.438  -33.896 -10.196 1.00 55.22  ? 79  THR C CG2 1 
ATOM   6833  N N   . PRO C 1 80  ? 39.153  -32.354 -7.535  1.00 46.00  ? 80  PRO C N   1 
ATOM   6834  C CA  . PRO C 1 80  ? 40.478  -32.393 -6.918  1.00 44.38  ? 80  PRO C CA  1 
ATOM   6835  C C   . PRO C 1 80  ? 41.584  -32.665 -7.918  1.00 45.87  ? 80  PRO C C   1 
ATOM   6836  O O   . PRO C 1 80  ? 41.352  -33.204 -9.006  1.00 45.77  ? 80  PRO C O   1 
ATOM   6837  C CB  . PRO C 1 80  ? 40.336  -33.534 -5.915  1.00 46.01  ? 80  PRO C CB  1 
ATOM   6838  C CG  . PRO C 1 80  ? 38.937  -33.367 -5.451  1.00 48.71  ? 80  PRO C CG  1 
ATOM   6839  C CD  . PRO C 1 80  ? 38.171  -33.089 -6.719  1.00 49.27  ? 80  PRO C CD  1 
ATOM   6840  N N   . LEU C 1 81  ? 42.805  -32.297 -7.548  1.00 40.52  ? 81  LEU C N   1 
ATOM   6841  C CA  . LEU C 1 81  ? 43.942  -32.418 -8.452  1.00 37.68  ? 81  LEU C CA  1 
ATOM   6842  C C   . LEU C 1 81  ? 44.558  -33.810 -8.303  1.00 44.06  ? 81  LEU C C   1 
ATOM   6843  O O   . LEU C 1 81  ? 45.693  -33.995 -7.853  1.00 44.81  ? 81  LEU C O   1 
ATOM   6844  C CB  . LEU C 1 81  ? 44.945  -31.305 -8.187  1.00 33.78  ? 81  LEU C CB  1 
ATOM   6845  C CG  . LEU C 1 81  ? 44.411  -29.882 -8.366  1.00 39.13  ? 81  LEU C CG  1 
ATOM   6846  C CD1 . LEU C 1 81  ? 45.525  -28.986 -8.852  1.00 35.37  ? 81  LEU C CD1 1 
ATOM   6847  C CD2 . LEU C 1 81  ? 43.252  -29.825 -9.338  1.00 37.61  ? 81  LEU C CD2 1 
ATOM   6848  N N   . SER C 1 82  ? 43.766  -34.801 -8.710  1.00 44.77  ? 82  SER C N   1 
ATOM   6849  C CA  . SER C 1 82  ? 44.118  -36.211 -8.648  1.00 40.41  ? 82  SER C CA  1 
ATOM   6850  C C   . SER C 1 82  ? 45.120  -36.566 -9.734  1.00 34.89  ? 82  SER C C   1 
ATOM   6851  O O   . SER C 1 82  ? 45.340  -35.809 -10.683 1.00 37.18  ? 82  SER C O   1 
ATOM   6852  C CB  . SER C 1 82  ? 42.883  -37.072 -8.841  1.00 35.15  ? 82  SER C CB  1 
ATOM   6853  O OG  . SER C 1 82  ? 42.592  -37.073 -10.225 1.00 43.82  ? 82  SER C OG  1 
ATOM   6854  N N   . GLU C 1 83  ? 45.718  -37.755 -9.596  1.00 36.31  ? 83  GLU C N   1 
ATOM   6855  C CA  . GLU C 1 83  ? 46.650  -38.238 -10.615 1.00 36.81  ? 83  GLU C CA  1 
ATOM   6856  C C   . GLU C 1 83  ? 45.991  -38.227 -11.990 1.00 38.27  ? 83  GLU C C   1 
ATOM   6857  O O   . GLU C 1 83  ? 46.544  -37.680 -12.947 1.00 36.49  ? 83  GLU C O   1 
ATOM   6858  C CB  . GLU C 1 83  ? 47.150  -39.645 -10.259 1.00 36.71  ? 83  GLU C CB  1 
ATOM   6859  C CG  . GLU C 1 83  ? 48.175  -39.725 -9.093  1.00 31.54  ? 83  GLU C CG  1 
ATOM   6860  C CD  . GLU C 1 83  ? 49.388  -38.802 -9.259  1.00 39.41  ? 83  GLU C CD  1 
ATOM   6861  O OE1 . GLU C 1 83  ? 49.300  -37.606 -8.878  1.00 39.00  ? 83  GLU C OE1 1 
ATOM   6862  O OE2 . GLU C 1 83  ? 50.461  -39.296 -9.703  1.00 41.27  ? 83  GLU C OE2 1 
ATOM   6863  N N   . ALA C 1 84  ? 44.773  -38.776 -12.083 1.00 41.65  ? 84  ALA C N   1 
ATOM   6864  C CA  . ALA C 1 84  ? 44.061  -38.841 -13.361 1.00 45.55  ? 84  ALA C CA  1 
ATOM   6865  C C   . ALA C 1 84  ? 43.898  -37.459 -13.992 1.00 38.45  ? 84  ALA C C   1 
ATOM   6866  O O   . ALA C 1 84  ? 44.147  -37.286 -15.192 1.00 39.87  ? 84  ALA C O   1 
ATOM   6867  C CB  . ALA C 1 84  ? 42.698  -39.511 -13.169 1.00 40.22  ? 84  ALA C CB  1 
ATOM   6868  N N   . VAL C 1 85  ? 43.505  -36.460 -13.202 1.00 36.11  ? 85  VAL C N   1 
ATOM   6869  C CA  . VAL C 1 85  ? 43.444  -35.101 -13.738 1.00 40.45  ? 85  VAL C CA  1 
ATOM   6870  C C   . VAL C 1 85  ? 44.806  -34.683 -14.267 1.00 39.80  ? 85  VAL C C   1 
ATOM   6871  O O   . VAL C 1 85  ? 44.916  -34.051 -15.327 1.00 42.29  ? 85  VAL C O   1 
ATOM   6872  C CB  . VAL C 1 85  ? 42.927  -34.117 -12.672 1.00 41.58  ? 85  VAL C CB  1 
ATOM   6873  C CG1 . VAL C 1 85  ? 43.008  -32.675 -13.177 1.00 42.79  ? 85  VAL C CG1 1 
ATOM   6874  C CG2 . VAL C 1 85  ? 41.507  -34.469 -12.278 1.00 46.11  ? 85  VAL C CG2 1 
ATOM   6875  N N   . LEU C 1 86  ? 45.870  -35.048 -13.557 1.00 39.50  ? 86  LEU C N   1 
ATOM   6876  C CA  . LEU C 1 86  ? 47.196  -34.662 -14.011 1.00 37.04  ? 86  LEU C CA  1 
ATOM   6877  C C   . LEU C 1 86  ? 47.597  -35.398 -15.289 1.00 39.86  ? 86  LEU C C   1 
ATOM   6878  O O   . LEU C 1 86  ? 48.518  -34.940 -15.977 1.00 26.70  ? 86  LEU C O   1 
ATOM   6879  C CB  . LEU C 1 86  ? 48.217  -34.890 -12.886 1.00 36.22  ? 86  LEU C CB  1 
ATOM   6880  C CG  . LEU C 1 86  ? 48.128  -34.156 -11.534 1.00 36.02  ? 86  LEU C CG  1 
ATOM   6881  C CD1 . LEU C 1 86  ? 49.411  -34.351 -10.702 1.00 32.82  ? 86  LEU C CD1 1 
ATOM   6882  C CD2 . LEU C 1 86  ? 47.876  -32.671 -11.713 1.00 34.14  ? 86  LEU C CD2 1 
ATOM   6883  N N   . GLN C 1 87  ? 46.902  -36.502 -15.627 1.00 35.55  ? 87  GLN C N   1 
ATOM   6884  C CA  . GLN C 1 87  ? 47.085  -37.284 -16.855 1.00 42.49  ? 87  GLN C CA  1 
ATOM   6885  C C   . GLN C 1 87  ? 46.288  -36.728 -18.038 1.00 41.76  ? 87  GLN C C   1 
ATOM   6886  O O   . GLN C 1 87  ? 46.805  -36.649 -19.154 1.00 39.19  ? 87  GLN C O   1 
ATOM   6887  C CB  . GLN C 1 87  ? 46.661  -38.747 -16.646 1.00 41.68  ? 87  GLN C CB  1 
ATOM   6888  C CG  . GLN C 1 87  ? 47.026  -39.371 -15.307 1.00 45.11  ? 87  GLN C CG  1 
ATOM   6889  C CD  . GLN C 1 87  ? 48.242  -40.282 -15.344 1.00 44.92  ? 87  GLN C CD  1 
ATOM   6890  O OE1 . GLN C 1 87  ? 49.246  -39.995 -15.993 1.00 46.56  ? 87  GLN C OE1 1 
ATOM   6891  N NE2 . GLN C 1 87  ? 48.153  -41.388 -14.626 1.00 44.29  ? 87  GLN C NE2 1 
ATOM   6892  N N   . ASP C 1 88  ? 45.014  -36.382 -17.810 1.00 47.15  ? 88  ASP C N   1 
ATOM   6893  C CA  . ASP C 1 88  ? 44.043  -35.887 -18.789 1.00 44.88  ? 88  ASP C CA  1 
ATOM   6894  C C   . ASP C 1 88  ? 44.655  -34.877 -19.757 1.00 45.36  ? 88  ASP C C   1 
ATOM   6895  O O   . ASP C 1 88  ? 45.062  -33.781 -19.346 1.00 46.48  ? 88  ASP C O   1 
ATOM   6896  C CB  . ASP C 1 88  ? 42.857  -35.272 -18.042 1.00 43.80  ? 88  ASP C CB  1 
ATOM   6897  C CG  . ASP C 1 88  ? 41.718  -34.830 -18.960 1.00 54.11  ? 88  ASP C CG  1 
ATOM   6898  O OD1 . ASP C 1 88  ? 41.932  -34.553 -20.166 1.00 51.65  ? 88  ASP C OD1 1 
ATOM   6899  O OD2 . ASP C 1 88  ? 40.579  -34.765 -18.451 1.00 57.01  ? 88  ASP C OD2 1 
ATOM   6900  N N   . PRO C 1 89  ? 44.708  -35.192 -21.055 1.00 44.96  ? 89  PRO C N   1 
ATOM   6901  C CA  . PRO C 1 89  ? 45.357  -34.272 -22.003 1.00 47.36  ? 89  PRO C CA  1 
ATOM   6902  C C   . PRO C 1 89  ? 44.672  -32.922 -22.092 1.00 45.95  ? 89  PRO C C   1 
ATOM   6903  O O   . PRO C 1 89  ? 45.316  -31.943 -22.494 1.00 43.22  ? 89  PRO C O   1 
ATOM   6904  C CB  . PRO C 1 89  ? 45.285  -35.029 -23.339 1.00 43.96  ? 89  PRO C CB  1 
ATOM   6905  C CG  . PRO C 1 89  ? 44.937  -36.441 -22.986 1.00 42.34  ? 89  PRO C CG  1 
ATOM   6906  C CD  . PRO C 1 89  ? 44.120  -36.353 -21.739 1.00 47.68  ? 89  PRO C CD  1 
ATOM   6907  N N   . GLU C 1 90  ? 43.386  -32.848 -21.739 1.00 48.71  ? 90  GLU C N   1 
ATOM   6908  C CA  . GLU C 1 90  ? 42.682  -31.571 -21.703 1.00 51.82  ? 90  GLU C CA  1 
ATOM   6909  C C   . GLU C 1 90  ? 43.224  -30.679 -20.597 1.00 50.98  ? 90  GLU C C   1 
ATOM   6910  O O   . GLU C 1 90  ? 43.387  -29.469 -20.798 1.00 52.11  ? 90  GLU C O   1 
ATOM   6911  C CB  . GLU C 1 90  ? 41.184  -31.800 -21.514 1.00 52.56  ? 90  GLU C CB  1 
ATOM   6912  C CG  . GLU C 1 90  ? 40.306  -30.768 -22.207 1.00 63.01  ? 90  GLU C CG  1 
ATOM   6913  C CD  . GLU C 1 90  ? 38.953  -30.592 -21.519 1.00 68.72  ? 90  GLU C CD  1 
ATOM   6914  O OE1 . GLU C 1 90  ? 38.884  -29.841 -20.518 1.00 64.46  ? 90  GLU C OE1 1 
ATOM   6915  O OE2 . GLU C 1 90  ? 37.961  -31.205 -21.976 1.00 66.57  ? 90  GLU C OE2 1 
ATOM   6916  N N   . PHE C 1 91  ? 43.498  -31.254 -19.421 1.00 48.93  ? 91  PHE C N   1 
ATOM   6917  C CA  . PHE C 1 91  ? 44.179  -30.494 -18.377 1.00 44.99  ? 91  PHE C CA  1 
ATOM   6918  C C   . PHE C 1 91  ? 45.557  -30.041 -18.842 1.00 43.80  ? 91  PHE C C   1 
ATOM   6919  O O   . PHE C 1 91  ? 45.945  -28.886 -18.634 1.00 42.13  ? 91  PHE C O   1 
ATOM   6920  C CB  . PHE C 1 91  ? 44.302  -31.329 -17.105 1.00 47.03  ? 91  PHE C CB  1 
ATOM   6921  C CG  . PHE C 1 91  ? 45.035  -30.625 -15.995 1.00 49.81  ? 91  PHE C CG  1 
ATOM   6922  C CD1 . PHE C 1 91  ? 44.665  -29.348 -15.605 1.00 45.89  ? 91  PHE C CD1 1 
ATOM   6923  C CD2 . PHE C 1 91  ? 46.128  -31.221 -15.377 1.00 45.98  ? 91  PHE C CD2 1 
ATOM   6924  C CE1 . PHE C 1 91  ? 45.339  -28.689 -14.586 1.00 48.73  ? 91  PHE C CE1 1 
ATOM   6925  C CE2 . PHE C 1 91  ? 46.814  -30.570 -14.367 1.00 47.59  ? 91  PHE C CE2 1 
ATOM   6926  C CZ  . PHE C 1 91  ? 46.417  -29.296 -13.968 1.00 51.81  ? 91  PHE C CZ  1 
ATOM   6927  N N   . ILE C 1 92  ? 46.313  -30.939 -19.479 1.00 41.90  ? 92  ILE C N   1 
ATOM   6928  C CA  . ILE C 1 92  ? 47.643  -30.578 -19.961 1.00 41.88  ? 92  ILE C CA  1 
ATOM   6929  C C   . ILE C 1 92  ? 47.556  -29.438 -20.972 1.00 44.03  ? 92  ILE C C   1 
ATOM   6930  O O   . ILE C 1 92  ? 48.223  -28.406 -20.824 1.00 41.45  ? 92  ILE C O   1 
ATOM   6931  C CB  . ILE C 1 92  ? 48.349  -31.810 -20.552 1.00 44.64  ? 92  ILE C CB  1 
ATOM   6932  C CG1 . ILE C 1 92  ? 48.255  -32.986 -19.588 1.00 40.60  ? 92  ILE C CG1 1 
ATOM   6933  C CG2 . ILE C 1 92  ? 49.815  -31.492 -20.887 1.00 47.35  ? 92  ILE C CG2 1 
ATOM   6934  C CD1 . ILE C 1 92  ? 49.096  -34.158 -20.002 1.00 39.60  ? 92  ILE C CD1 1 
ATOM   6935  N N   . ASP C 1 93  ? 46.737  -29.615 -22.018 1.00 43.38  ? 93  ASP C N   1 
ATOM   6936  C CA  . ASP C 1 93  ? 46.522  -28.566 -23.015 1.00 43.62  ? 93  ASP C CA  1 
ATOM   6937  C C   . ASP C 1 93  ? 46.259  -27.213 -22.362 1.00 38.05  ? 93  ASP C C   1 
ATOM   6938  O O   . ASP C 1 93  ? 46.885  -26.211 -22.721 1.00 36.86  ? 93  ASP C O   1 
ATOM   6939  C CB  . ASP C 1 93  ? 45.359  -28.954 -23.926 1.00 48.18  ? 93  ASP C CB  1 
ATOM   6940  C CG  . ASP C 1 93  ? 45.774  -29.931 -25.021 1.00 58.59  ? 93  ASP C CG  1 
ATOM   6941  O OD1 . ASP C 1 93  ? 46.602  -30.835 -24.752 1.00 58.87  ? 93  ASP C OD1 1 
ATOM   6942  O OD2 . ASP C 1 93  ? 45.267  -29.797 -26.156 1.00 60.15  ? 93  ASP C OD2 1 
ATOM   6943  N N   . ARG C 1 94  ? 45.347  -27.174 -21.381 1.00 40.95  ? 94  ARG C N   1 
ATOM   6944  C CA  . ARG C 1 94  ? 45.065  -25.935 -20.656 1.00 41.43  ? 94  ARG C CA  1 
ATOM   6945  C C   . ARG C 1 94  ? 46.344  -25.290 -20.149 1.00 40.26  ? 94  ARG C C   1 
ATOM   6946  O O   . ARG C 1 94  ? 46.548  -24.080 -20.303 1.00 38.53  ? 94  ARG C O   1 
ATOM   6947  C CB  . ARG C 1 94  ? 44.112  -26.204 -19.488 1.00 44.10  ? 94  ARG C CB  1 
ATOM   6948  C CG  . ARG C 1 94  ? 42.646  -25.898 -19.772 1.00 44.06  ? 94  ARG C CG  1 
ATOM   6949  C CD  . ARG C 1 94  ? 41.788  -26.077 -18.528 1.00 48.72  ? 94  ARG C CD  1 
ATOM   6950  N NE  . ARG C 1 94  ? 41.853  -27.446 -18.031 1.00 54.29  ? 94  ARG C NE  1 
ATOM   6951  C CZ  . ARG C 1 94  ? 40.850  -28.317 -18.063 1.00 60.09  ? 94  ARG C CZ  1 
ATOM   6952  N NH1 . ARG C 1 94  ? 39.660  -27.992 -18.548 1.00 59.99  ? 94  ARG C NH1 1 
ATOM   6953  N NH2 . ARG C 1 94  ? 41.044  -29.547 -17.594 1.00 50.74  ? 94  ARG C NH2 1 
ATOM   6954  N N   . LEU C 1 95  ? 47.233  -26.095 -19.555 1.00 42.60  ? 95  LEU C N   1 
ATOM   6955  C CA  . LEU C 1 95  ? 48.502  -25.570 -19.061 1.00 39.97  ? 95  LEU C CA  1 
ATOM   6956  C C   . LEU C 1 95  ? 49.445  -25.206 -20.202 1.00 40.10  ? 95  LEU C C   1 
ATOM   6957  O O   . LEU C 1 95  ? 50.246  -24.272 -20.066 1.00 40.52  ? 95  LEU C O   1 
ATOM   6958  C CB  . LEU C 1 95  ? 49.168  -26.587 -18.117 1.00 40.56  ? 95  LEU C CB  1 
ATOM   6959  C CG  . LEU C 1 95  ? 48.418  -26.879 -16.816 1.00 37.53  ? 95  LEU C CG  1 
ATOM   6960  C CD1 . LEU C 1 95  ? 49.265  -27.663 -15.857 1.00 35.79  ? 95  LEU C CD1 1 
ATOM   6961  C CD2 . LEU C 1 95  ? 47.973  -25.589 -16.176 1.00 35.90  ? 95  LEU C CD2 1 
ATOM   6962  N N   . ALA C 1 96  ? 49.367  -25.915 -21.330 1.00 37.28  ? 96  ALA C N   1 
ATOM   6963  C CA  . ALA C 1 96  ? 50.318  -25.664 -22.413 1.00 40.30  ? 96  ALA C CA  1 
ATOM   6964  C C   . ALA C 1 96  ? 50.127  -24.288 -23.042 1.00 39.94  ? 96  ALA C C   1 
ATOM   6965  O O   . ALA C 1 96  ? 51.093  -23.716 -23.563 1.00 41.61  ? 96  ALA C O   1 
ATOM   6966  C CB  . ALA C 1 96  ? 50.219  -26.754 -23.481 1.00 42.80  ? 96  ALA C CB  1 
ATOM   6967  N N   . ALA C 1 97  ? 48.910  -23.737 -22.994 1.00 37.81  ? 97  ALA C N   1 
ATOM   6968  C CA  . ALA C 1 97  ? 48.696  -22.374 -23.486 1.00 46.35  ? 97  ALA C CA  1 
ATOM   6969  C C   . ALA C 1 97  ? 49.664  -21.395 -22.840 1.00 41.92  ? 97  ALA C C   1 
ATOM   6970  O O   . ALA C 1 97  ? 50.220  -20.517 -23.511 1.00 39.61  ? 97  ALA C O   1 
ATOM   6971  C CB  . ALA C 1 97  ? 47.257  -21.924 -23.221 1.00 39.06  ? 97  ALA C CB  1 
ATOM   6972  N N   . HIS C 1 98  ? 49.871  -21.527 -21.531 1.00 40.53  ? 98  HIS C N   1 
ATOM   6973  C CA  . HIS C 1 98  ? 50.823  -20.664 -20.848 1.00 37.84  ? 98  HIS C CA  1 
ATOM   6974  C C   . HIS C 1 98  ? 52.249  -21.119 -21.083 1.00 41.51  ? 98  HIS C C   1 
ATOM   6975  O O   . HIS C 1 98  ? 53.142  -20.299 -21.319 1.00 46.94  ? 98  HIS C O   1 
ATOM   6976  C CB  . HIS C 1 98  ? 50.552  -20.664 -19.349 1.00 41.31  ? 98  HIS C CB  1 
ATOM   6977  C CG  . HIS C 1 98  ? 49.261  -20.030 -18.961 1.00 34.41  ? 98  HIS C CG  1 
ATOM   6978  N ND1 . HIS C 1 98  ? 49.087  -18.663 -18.929 1.00 35.22  ? 98  HIS C ND1 1 
ATOM   6979  C CD2 . HIS C 1 98  ? 48.099  -20.571 -18.530 1.00 38.18  ? 98  HIS C CD2 1 
ATOM   6980  C CE1 . HIS C 1 98  ? 47.862  -18.391 -18.516 1.00 38.03  ? 98  HIS C CE1 1 
ATOM   6981  N NE2 . HIS C 1 98  ? 47.245  -19.531 -18.262 1.00 36.77  ? 98  HIS C NE2 1 
ATOM   6982  N N   . THR C 1 99  ? 52.477  -22.421 -20.998 1.00 38.83  ? 99  THR C N   1 
ATOM   6983  C CA  . THR C 1 99  ? 53.838  -22.915 -20.925 1.00 42.36  ? 99  THR C CA  1 
ATOM   6984  C C   . THR C 1 99  ? 54.521  -22.920 -22.293 1.00 43.64  ? 99  THR C C   1 
ATOM   6985  O O   . THR C 1 99  ? 55.751  -22.830 -22.362 1.00 42.75  ? 99  THR C O   1 
ATOM   6986  C CB  . THR C 1 99  ? 53.822  -24.298 -20.268 1.00 39.14  ? 99  THR C CB  1 
ATOM   6987  O OG1 . THR C 1 99  ? 55.043  -24.493 -19.549 1.00 51.65  ? 99  THR C OG1 1 
ATOM   6988  C CG2 . THR C 1 99  ? 53.645  -25.401 -21.286 1.00 34.13  ? 99  THR C CG2 1 
ATOM   6989  N N   . GLY C 1 100 ? 53.758  -22.998 -23.383 1.00 39.88  ? 100 GLY C N   1 
ATOM   6990  C CA  . GLY C 1 100 ? 54.342  -22.779 -24.702 1.00 44.58  ? 100 GLY C CA  1 
ATOM   6991  C C   . GLY C 1 100 ? 55.458  -23.758 -25.047 1.00 47.49  ? 100 GLY C C   1 
ATOM   6992  O O   . GLY C 1 100 ? 55.237  -24.968 -25.183 1.00 45.71  ? 100 GLY C O   1 
ATOM   6993  N N   . THR C 1 101 ? 56.677  -23.238 -25.218 1.00 48.99  ? 101 THR C N   1 
ATOM   6994  C CA  . THR C 1 101 ? 57.829  -24.078 -25.539 1.00 50.25  ? 101 THR C CA  1 
ATOM   6995  C C   . THR C 1 101 ? 58.471  -24.699 -24.307 1.00 50.54  ? 101 THR C C   1 
ATOM   6996  O O   . THR C 1 101 ? 59.438  -25.456 -24.444 1.00 46.04  ? 101 THR C O   1 
ATOM   6997  C CB  . THR C 1 101 ? 58.893  -23.276 -26.293 1.00 50.97  ? 101 THR C CB  1 
ATOM   6998  O OG1 . THR C 1 101 ? 59.805  -22.689 -25.356 1.00 51.54  ? 101 THR C OG1 1 
ATOM   6999  C CG2 . THR C 1 101 ? 58.249  -22.169 -27.117 1.00 52.20  ? 101 THR C CG2 1 
ATOM   7000  N N   . GLY C 1 102 ? 57.966  -24.389 -23.112 1.00 51.68  ? 102 GLY C N   1 
ATOM   7001  C CA  . GLY C 1 102 ? 58.568  -24.838 -21.878 1.00 42.49  ? 102 GLY C CA  1 
ATOM   7002  C C   . GLY C 1 102 ? 59.698  -23.975 -21.367 1.00 50.53  ? 102 GLY C C   1 
ATOM   7003  O O   . GLY C 1 102 ? 60.015  -24.041 -20.169 1.00 51.21  ? 102 GLY C O   1 
ATOM   7004  N N   . ALA C 1 103 ? 60.316  -23.165 -22.226 1.00 49.86  ? 103 ALA C N   1 
ATOM   7005  C CA  . ALA C 1 103 ? 61.384  -22.280 -21.782 1.00 48.47  ? 103 ALA C CA  1 
ATOM   7006  C C   . ALA C 1 103 ? 60.887  -21.352 -20.674 1.00 47.04  ? 103 ALA C C   1 
ATOM   7007  O O   . ALA C 1 103 ? 59.820  -20.740 -20.787 1.00 47.73  ? 103 ALA C O   1 
ATOM   7008  C CB  . ALA C 1 103 ? 61.916  -21.474 -22.967 1.00 41.70  ? 103 ALA C CB  1 
ATOM   7009  N N   . GLY C 1 104 ? 61.641  -21.296 -19.576 1.00 50.41  ? 104 GLY C N   1 
ATOM   7010  C CA  . GLY C 1 104 ? 61.373  -20.379 -18.483 1.00 47.65  ? 104 GLY C CA  1 
ATOM   7011  C C   . GLY C 1 104 ? 60.280  -20.775 -17.512 1.00 47.22  ? 104 GLY C C   1 
ATOM   7012  O O   . GLY C 1 104 ? 59.887  -19.944 -16.684 1.00 46.79  ? 104 GLY C O   1 
ATOM   7013  N N   . TRP C 1 105 ? 59.775  -22.004 -17.568 1.00 41.82  ? 105 TRP C N   1 
ATOM   7014  C CA  . TRP C 1 105 ? 58.641  -22.406 -16.744 1.00 39.04  ? 105 TRP C CA  1 
ATOM   7015  C C   . TRP C 1 105 ? 59.024  -23.600 -15.884 1.00 36.10  ? 105 TRP C C   1 
ATOM   7016  O O   . TRP C 1 105 ? 59.969  -24.331 -16.191 1.00 41.55  ? 105 TRP C O   1 
ATOM   7017  C CB  . TRP C 1 105 ? 57.427  -22.769 -17.607 1.00 41.91  ? 105 TRP C CB  1 
ATOM   7018  C CG  . TRP C 1 105 ? 56.641  -21.593 -18.078 1.00 42.87  ? 105 TRP C CG  1 
ATOM   7019  C CD1 . TRP C 1 105 ? 56.885  -20.834 -19.187 1.00 43.24  ? 105 TRP C CD1 1 
ATOM   7020  C CD2 . TRP C 1 105 ? 55.475  -21.048 -17.468 1.00 41.82  ? 105 TRP C CD2 1 
ATOM   7021  N NE1 . TRP C 1 105 ? 55.944  -19.845 -19.302 1.00 37.27  ? 105 TRP C NE1 1 
ATOM   7022  C CE2 . TRP C 1 105 ? 55.063  -19.953 -18.260 1.00 42.16  ? 105 TRP C CE2 1 
ATOM   7023  C CE3 . TRP C 1 105 ? 54.737  -21.375 -16.327 1.00 40.48  ? 105 TRP C CE3 1 
ATOM   7024  C CZ2 . TRP C 1 105 ? 53.948  -19.181 -17.945 1.00 39.00  ? 105 TRP C CZ2 1 
ATOM   7025  C CZ3 . TRP C 1 105 ? 53.633  -20.606 -16.009 1.00 40.38  ? 105 TRP C CZ3 1 
ATOM   7026  C CH2 . TRP C 1 105 ? 53.248  -19.518 -16.818 1.00 45.70  ? 105 TRP C CH2 1 
ATOM   7027  N N   . SER C 1 106 ? 58.275  -23.805 -14.804 1.00 33.94  ? 106 SER C N   1 
ATOM   7028  C CA  . SER C 1 106 ? 58.519  -24.957 -13.943 1.00 34.27  ? 106 SER C CA  1 
ATOM   7029  C C   . SER C 1 106 ? 57.270  -25.270 -13.139 1.00 32.37  ? 106 SER C C   1 
ATOM   7030  O O   . SER C 1 106 ? 56.408  -24.417 -12.950 1.00 34.06  ? 106 SER C O   1 
ATOM   7031  C CB  . SER C 1 106 ? 59.687  -24.716 -12.990 1.00 34.09  ? 106 SER C CB  1 
ATOM   7032  O OG  . SER C 1 106 ? 59.234  -23.972 -11.883 1.00 37.59  ? 106 SER C OG  1 
ATOM   7033  N N   . LEU C 1 107 ? 57.197  -26.504 -12.648 1.00 31.06  ? 107 LEU C N   1 
ATOM   7034  C CA  . LEU C 1 107 ? 56.076  -26.965 -11.844 1.00 29.19  ? 107 LEU C CA  1 
ATOM   7035  C C   . LEU C 1 107 ? 56.421  -26.868 -10.363 1.00 32.89  ? 107 LEU C C   1 
ATOM   7036  O O   . LEU C 1 107 ? 57.520  -27.241 -9.942  1.00 28.11  ? 107 LEU C O   1 
ATOM   7037  C CB  . LEU C 1 107 ? 55.708  -28.400 -12.202 1.00 27.02  ? 107 LEU C CB  1 
ATOM   7038  C CG  . LEU C 1 107 ? 54.365  -28.899 -11.694 1.00 30.81  ? 107 LEU C CG  1 
ATOM   7039  C CD1 . LEU C 1 107 ? 53.228  -28.146 -12.389 1.00 24.79  ? 107 LEU C CD1 1 
ATOM   7040  C CD2 . LEU C 1 107 ? 54.250  -30.432 -11.878 1.00 26.87  ? 107 LEU C CD2 1 
ATOM   7041  N N   . PHE C 1 108 ? 55.474  -26.347 -9.575  1.00 31.12  ? 108 PHE C N   1 
ATOM   7042  C CA  . PHE C 1 108 ? 55.641  -26.130 -8.139  1.00 31.13  ? 108 PHE C CA  1 
ATOM   7043  C C   . PHE C 1 108 ? 54.565  -26.944 -7.454  1.00 29.85  ? 108 PHE C C   1 
ATOM   7044  O O   . PHE C 1 108 ? 53.536  -26.389 -7.050  1.00 34.42  ? 108 PHE C O   1 
ATOM   7045  C CB  . PHE C 1 108 ? 55.502  -24.662 -7.754  1.00 30.19  ? 108 PHE C CB  1 
ATOM   7046  C CG  . PHE C 1 108 ? 55.925  -24.346 -6.334  1.00 33.59  ? 108 PHE C CG  1 
ATOM   7047  C CD1 . PHE C 1 108 ? 57.268  -24.395 -5.954  1.00 30.51  ? 108 PHE C CD1 1 
ATOM   7048  C CD2 . PHE C 1 108 ? 54.974  -23.977 -5.382  1.00 31.70  ? 108 PHE C CD2 1 
ATOM   7049  C CE1 . PHE C 1 108 ? 57.650  -24.086 -4.640  1.00 34.94  ? 108 PHE C CE1 1 
ATOM   7050  C CE2 . PHE C 1 108 ? 55.346  -23.669 -4.073  1.00 32.24  ? 108 PHE C CE2 1 
ATOM   7051  C CZ  . PHE C 1 108 ? 56.685  -23.725 -3.698  1.00 31.56  ? 108 PHE C CZ  1 
ATOM   7052  N N   . PRO C 1 109 ? 54.765  -28.250 -7.306  1.00 30.12  ? 109 PRO C N   1 
ATOM   7053  C CA  . PRO C 1 109 ? 53.713  -29.120 -6.780  1.00 29.81  ? 109 PRO C CA  1 
ATOM   7054  C C   . PRO C 1 109 ? 53.786  -29.259 -5.270  1.00 32.72  ? 109 PRO C C   1 
ATOM   7055  O O   . PRO C 1 109 ? 54.850  -29.209 -4.653  1.00 28.55  ? 109 PRO C O   1 
ATOM   7056  C CB  . PRO C 1 109 ? 54.017  -30.464 -7.461  1.00 30.84  ? 109 PRO C CB  1 
ATOM   7057  C CG  . PRO C 1 109 ? 55.532  -30.470 -7.535  1.00 29.29  ? 109 PRO C CG  1 
ATOM   7058  C CD  . PRO C 1 109 ? 55.972  -29.008 -7.673  1.00 23.38  ? 109 PRO C CD  1 
ATOM   7059  N N   . CYS C 1 110 ? 52.610  -29.440 -4.681  1.00 35.23  ? 110 CYS C N   1 
ATOM   7060  C CA  . CYS C 1 110 ? 52.525  -29.814 -3.277  1.00 31.46  ? 110 CYS C CA  1 
ATOM   7061  C C   . CYS C 1 110 ? 53.040  -31.228 -3.028  1.00 32.28  ? 110 CYS C C   1 
ATOM   7062  O O   . CYS C 1 110 ? 53.683  -31.484 -2.002  1.00 28.54  ? 110 CYS C O   1 
ATOM   7063  C CB  . CYS C 1 110 ? 51.087  -29.669 -2.816  1.00 29.00  ? 110 CYS C CB  1 
ATOM   7064  S SG  . CYS C 1 110 ? 50.782  -30.312 -1.184  1.00 32.69  ? 110 CYS C SG  1 
ATOM   7065  N N   . VAL C 1 111 ? 52.760  -32.163 -3.934  1.00 29.15  ? 111 VAL C N   1 
ATOM   7066  C CA  . VAL C 1 111 ? 53.311  -33.514 -3.848  1.00 28.98  ? 111 VAL C CA  1 
ATOM   7067  C C   . VAL C 1 111 ? 53.993  -33.838 -5.174  1.00 32.53  ? 111 VAL C C   1 
ATOM   7068  O O   . VAL C 1 111 ? 53.419  -33.613 -6.246  1.00 32.61  ? 111 VAL C O   1 
ATOM   7069  C CB  . VAL C 1 111 ? 52.247  -34.584 -3.499  1.00 31.68  ? 111 VAL C CB  1 
ATOM   7070  C CG1 . VAL C 1 111 ? 52.912  -35.880 -3.209  1.00 32.08  ? 111 VAL C CG1 1 
ATOM   7071  C CG2 . VAL C 1 111 ? 51.460  -34.237 -2.240  1.00 30.24  ? 111 VAL C CG2 1 
ATOM   7072  N N   . SER C 1 112 ? 55.226  -34.344 -5.098  1.00 29.48  ? 112 SER C N   1 
ATOM   7073  C CA  . SER C 1 112 ? 55.988  -34.749 -6.281  1.00 30.91  ? 112 SER C CA  1 
ATOM   7074  C C   . SER C 1 112 ? 55.641  -36.195 -6.641  1.00 35.17  ? 112 SER C C   1 
ATOM   7075  O O   . SER C 1 112 ? 56.450  -37.114 -6.501  1.00 34.25  ? 112 SER C O   1 
ATOM   7076  C CB  . SER C 1 112 ? 57.486  -34.600 -6.037  1.00 27.56  ? 112 SER C CB  1 
ATOM   7077  O OG  . SER C 1 112 ? 57.882  -33.235 -6.006  1.00 40.20  ? 112 SER C OG  1 
ATOM   7078  N N   . THR C 1 113 ? 54.413  -36.378 -7.123  1.00 29.74  ? 113 THR C N   1 
ATOM   7079  C CA  . THR C 1 113 ? 53.928  -37.695 -7.500  1.00 28.93  ? 113 THR C CA  1 
ATOM   7080  C C   . THR C 1 113 ? 54.456  -38.083 -8.873  1.00 28.15  ? 113 THR C C   1 
ATOM   7081  O O   . THR C 1 113 ? 55.181  -37.333 -9.519  1.00 29.13  ? 113 THR C O   1 
ATOM   7082  C CB  . THR C 1 113 ? 52.402  -37.745 -7.512  1.00 33.17  ? 113 THR C CB  1 
ATOM   7083  O OG1 . THR C 1 113 ? 51.902  -36.898 -8.557  1.00 36.14  ? 113 THR C OG1 1 
ATOM   7084  C CG2 . THR C 1 113 ? 51.836  -37.299 -6.180  1.00 31.76  ? 113 THR C CG2 1 
ATOM   7085  N N   . ARG C 1 114 ? 54.074  -39.289 -9.312  1.00 35.50  ? 114 ARG C N   1 
ATOM   7086  C CA  . ARG C 1 114 ? 54.438  -39.786 -10.640 1.00 31.81  ? 114 ARG C CA  1 
ATOM   7087  C C   . ARG C 1 114 ? 53.814  -38.930 -11.739 1.00 30.97  ? 114 ARG C C   1 
ATOM   7088  O O   . ARG C 1 114 ? 54.492  -38.517 -12.687 1.00 30.32  ? 114 ARG C O   1 
ATOM   7089  C CB  . ARG C 1 114 ? 53.992  -41.247 -10.785 1.00 29.43  ? 114 ARG C CB  1 
ATOM   7090  C CG  . ARG C 1 114 ? 54.457  -41.966 -12.060 1.00 30.08  ? 114 ARG C CG  1 
ATOM   7091  C CD  . ARG C 1 114 ? 54.131  -43.452 -11.980 1.00 31.29  ? 114 ARG C CD  1 
ATOM   7092  N NE  . ARG C 1 114 ? 53.919  -44.077 -13.281 1.00 28.53  ? 114 ARG C NE  1 
ATOM   7093  C CZ  . ARG C 1 114 ? 54.894  -44.465 -14.093 1.00 31.68  ? 114 ARG C CZ  1 
ATOM   7094  N NH1 . ARG C 1 114 ? 56.168  -44.259 -13.793 1.00 25.13  ? 114 ARG C NH1 1 
ATOM   7095  N NH2 . ARG C 1 114 ? 54.585  -45.092 -15.228 1.00 33.98  ? 114 ARG C NH2 1 
ATOM   7096  N N   . ALA C 1 115 ? 52.513  -38.671 -11.639 1.00 28.37  ? 115 ALA C N   1 
ATOM   7097  C CA  . ALA C 1 115 ? 51.863  -37.857 -12.657 1.00 29.48  ? 115 ALA C CA  1 
ATOM   7098  C C   . ALA C 1 115 ? 52.469  -36.461 -12.706 1.00 30.64  ? 115 ALA C C   1 
ATOM   7099  O O   . ALA C 1 115 ? 52.693  -35.913 -13.793 1.00 28.30  ? 115 ALA C O   1 
ATOM   7100  C CB  . ALA C 1 115 ? 50.359  -37.804 -12.401 1.00 31.37  ? 115 ALA C CB  1 
ATOM   7101  N N   . ALA C 1 116 ? 52.785  -35.885 -11.537 1.00 34.33  ? 116 ALA C N   1 
ATOM   7102  C CA  . ALA C 1 116 ? 53.436  -34.575 -11.517 1.00 32.79  ? 116 ALA C CA  1 
ATOM   7103  C C   . ALA C 1 116 ? 54.758  -34.614 -12.263 1.00 31.36  ? 116 ALA C C   1 
ATOM   7104  O O   . ALA C 1 116 ? 55.078  -33.703 -13.037 1.00 28.38  ? 116 ALA C O   1 
ATOM   7105  C CB  . ALA C 1 116 ? 53.668  -34.106 -10.080 1.00 29.97  ? 116 ALA C CB  1 
ATOM   7106  N N   . ALA C 1 117 ? 55.555  -35.649 -12.022 1.00 30.13  ? 117 ALA C N   1 
ATOM   7107  C CA  . ALA C 1 117 ? 56.800  -35.772 -12.761 1.00 30.81  ? 117 ALA C CA  1 
ATOM   7108  C C   . ALA C 1 117 ? 56.525  -35.933 -14.251 1.00 31.13  ? 117 ALA C C   1 
ATOM   7109  O O   . ALA C 1 117 ? 57.190  -35.300 -15.083 1.00 32.20  ? 117 ALA C O   1 
ATOM   7110  C CB  . ALA C 1 117 ? 57.612  -36.950 -12.220 1.00 33.51  ? 117 ALA C CB  1 
ATOM   7111  N N   . GLN C 1 118 ? 55.544  -36.783 -14.601 1.00 28.84  ? 118 GLN C N   1 
ATOM   7112  C CA  . GLN C 1 118 ? 55.150  -36.961 -15.999 1.00 33.24  ? 118 GLN C CA  1 
ATOM   7113  C C   . GLN C 1 118 ? 54.731  -35.629 -16.613 1.00 35.34  ? 118 GLN C C   1 
ATOM   7114  O O   . GLN C 1 118 ? 55.091  -35.312 -17.757 1.00 32.53  ? 118 GLN C O   1 
ATOM   7115  C CB  . GLN C 1 118 ? 53.999  -37.978 -16.095 1.00 28.37  ? 118 GLN C CB  1 
ATOM   7116  C CG  . GLN C 1 118 ? 54.407  -39.435 -15.939 1.00 26.66  ? 118 GLN C CG  1 
ATOM   7117  C CD  . GLN C 1 118 ? 53.226  -40.381 -15.709 1.00 30.79  ? 118 GLN C CD  1 
ATOM   7118  O OE1 . GLN C 1 118 ? 52.278  -40.070 -14.987 1.00 33.40  ? 118 GLN C OE1 1 
ATOM   7119  N NE2 . GLN C 1 118 ? 53.289  -41.552 -16.329 1.00 38.51  ? 118 GLN C NE2 1 
ATOM   7120  N N   . LEU C 1 119 ? 53.983  -34.830 -15.847 1.00 29.25  ? 119 LEU C N   1 
ATOM   7121  C CA  . LEU C 1 119 ? 53.552  -33.520 -16.313 1.00 33.33  ? 119 LEU C CA  1 
ATOM   7122  C C   . LEU C 1 119 ? 54.732  -32.659 -16.728 1.00 38.17  ? 119 LEU C C   1 
ATOM   7123  O O   . LEU C 1 119 ? 54.617  -31.885 -17.683 1.00 39.42  ? 119 LEU C O   1 
ATOM   7124  C CB  . LEU C 1 119 ? 52.719  -32.826 -15.231 1.00 32.99  ? 119 LEU C CB  1 
ATOM   7125  C CG  . LEU C 1 119 ? 52.001  -31.526 -15.607 1.00 35.36  ? 119 LEU C CG  1 
ATOM   7126  C CD1 . LEU C 1 119 ? 50.905  -31.762 -16.644 1.00 32.78  ? 119 LEU C CD1 1 
ATOM   7127  C CD2 . LEU C 1 119 ? 51.413  -30.937 -14.359 1.00 32.99  ? 119 LEU C CD2 1 
ATOM   7128  N N   . THR C 1 120 ? 55.880  -32.785 -16.052 1.00 36.35  ? 120 THR C N   1 
ATOM   7129  C CA  . THR C 1 120 ? 57.002  -31.933 -16.431 1.00 37.72  ? 120 THR C CA  1 
ATOM   7130  C C   . THR C 1 120 ? 57.591  -32.349 -17.774 1.00 39.67  ? 120 THR C C   1 
ATOM   7131  O O   . THR C 1 120 ? 58.036  -31.487 -18.546 1.00 41.75  ? 120 THR C O   1 
ATOM   7132  C CB  . THR C 1 120 ? 58.084  -31.911 -15.338 1.00 39.13  ? 120 THR C CB  1 
ATOM   7133  O OG1 . THR C 1 120 ? 58.638  -33.221 -15.134 1.00 34.54  ? 120 THR C OG1 1 
ATOM   7134  C CG2 . THR C 1 120 ? 57.498  -31.394 -14.041 1.00 36.69  ? 120 THR C CG2 1 
ATOM   7135  N N   . ARG C 1 121 ? 57.589  -33.647 -18.089 1.00 38.98  ? 121 ARG C N   1 
ATOM   7136  C CA  . ARG C 1 121 ? 58.104  -34.046 -19.394 1.00 39.00  ? 121 ARG C CA  1 
ATOM   7137  C C   . ARG C 1 121 ? 57.133  -33.698 -20.511 1.00 36.21  ? 121 ARG C C   1 
ATOM   7138  O O   . ARG C 1 121 ? 57.555  -33.235 -21.572 1.00 37.50  ? 121 ARG C O   1 
ATOM   7139  C CB  . ARG C 1 121 ? 58.427  -35.539 -19.414 1.00 41.38  ? 121 ARG C CB  1 
ATOM   7140  C CG  . ARG C 1 121 ? 59.716  -35.828 -18.683 1.00 45.66  ? 121 ARG C CG  1 
ATOM   7141  C CD  . ARG C 1 121 ? 60.881  -35.826 -19.644 1.00 44.49  ? 121 ARG C CD  1 
ATOM   7142  N NE  . ARG C 1 121 ? 61.395  -37.171 -19.852 1.00 53.54  ? 121 ARG C NE  1 
ATOM   7143  C CZ  . ARG C 1 121 ? 62.211  -37.785 -19.009 1.00 53.70  ? 121 ARG C CZ  1 
ATOM   7144  N NH1 . ARG C 1 121 ? 62.648  -37.185 -17.909 1.00 49.93  ? 121 ARG C NH1 1 
ATOM   7145  N NH2 . ARG C 1 121 ? 62.609  -39.026 -19.279 1.00 59.64  ? 121 ARG C NH2 1 
ATOM   7146  N N   . LYS C 1 122 ? 55.835  -33.907 -20.287 1.00 36.47  ? 122 LYS C N   1 
ATOM   7147  C CA  . LYS C 1 122 ? 54.852  -33.626 -21.329 1.00 38.19  ? 122 LYS C CA  1 
ATOM   7148  C C   . LYS C 1 122 ? 54.788  -32.135 -21.648 1.00 42.20  ? 122 LYS C C   1 
ATOM   7149  O O   . LYS C 1 122 ? 54.679  -31.748 -22.818 1.00 42.51  ? 122 LYS C O   1 
ATOM   7150  C CB  . LYS C 1 122 ? 53.479  -34.155 -20.909 1.00 36.49  ? 122 LYS C CB  1 
ATOM   7151  C CG  . LYS C 1 122 ? 53.091  -35.461 -21.597 1.00 41.50  ? 122 LYS C CG  1 
ATOM   7152  C CD  . LYS C 1 122 ? 51.887  -36.124 -20.934 1.00 44.90  ? 122 LYS C CD  1 
ATOM   7153  C CE  . LYS C 1 122 ? 52.202  -36.591 -19.511 1.00 46.54  ? 122 LYS C CE  1 
ATOM   7154  N NZ  . LYS C 1 122 ? 51.033  -37.208 -18.773 1.00 38.66  ? 122 LYS C NZ  1 
ATOM   7155  N N   . LEU C 1 123 ? 54.860  -31.276 -20.628 1.00 42.40  ? 123 LEU C N   1 
ATOM   7156  C CA  . LEU C 1 123 ? 54.897  -29.843 -20.896 1.00 39.81  ? 123 LEU C CA  1 
ATOM   7157  C C   . LEU C 1 123 ? 56.285  -29.361 -21.280 1.00 43.16  ? 123 LEU C C   1 
ATOM   7158  O O   . LEU C 1 123 ? 56.422  -28.209 -21.713 1.00 46.76  ? 123 LEU C O   1 
ATOM   7159  C CB  . LEU C 1 123 ? 54.420  -29.037 -19.687 1.00 36.77  ? 123 LEU C CB  1 
ATOM   7160  C CG  . LEU C 1 123 ? 52.942  -29.089 -19.296 1.00 41.96  ? 123 LEU C CG  1 
ATOM   7161  C CD1 . LEU C 1 123 ? 52.740  -28.487 -17.912 1.00 32.82  ? 123 LEU C CD1 1 
ATOM   7162  C CD2 . LEU C 1 123 ? 52.033  -28.421 -20.337 1.00 42.95  ? 123 LEU C CD2 1 
ATOM   7163  N N   . ASN C 1 124 ? 57.307  -30.202 -21.124 1.00 43.04  ? 124 ASN C N   1 
ATOM   7164  C CA  . ASN C 1 124 ? 58.697  -29.823 -21.384 1.00 40.80  ? 124 ASN C CA  1 
ATOM   7165  C C   . ASN C 1 124 ? 59.093  -28.586 -20.579 1.00 48.74  ? 124 ASN C C   1 
ATOM   7166  O O   . ASN C 1 124 ? 59.679  -27.631 -21.098 1.00 46.27  ? 124 ASN C O   1 
ATOM   7167  C CB  . ASN C 1 124 ? 58.951  -29.594 -22.873 1.00 36.47  ? 124 ASN C CB  1 
ATOM   7168  C CG  . ASN C 1 124 ? 60.428  -29.594 -23.205 1.00 42.90  ? 124 ASN C CG  1 
ATOM   7169  O OD1 . ASN C 1 124 ? 61.186  -30.414 -22.684 1.00 40.65  ? 124 ASN C OD1 1 
ATOM   7170  N ND2 . ASN C 1 124 ? 60.851  -28.668 -24.064 1.00 43.14  ? 124 ASN C ND2 1 
ATOM   7171  N N   . VAL C 1 125 ? 58.758  -28.604 -19.289 1.00 45.78  ? 125 VAL C N   1 
ATOM   7172  C CA  . VAL C 1 125 ? 59.278  -27.592 -18.382 1.00 42.75  ? 125 VAL C CA  1 
ATOM   7173  C C   . VAL C 1 125 ? 60.546  -28.155 -17.764 1.00 41.87  ? 125 VAL C C   1 
ATOM   7174  O O   . VAL C 1 125 ? 60.939  -29.286 -18.066 1.00 45.67  ? 125 VAL C O   1 
ATOM   7175  C CB  . VAL C 1 125 ? 58.250  -27.200 -17.305 1.00 43.71  ? 125 VAL C CB  1 
ATOM   7176  C CG1 . VAL C 1 125 ? 56.989  -26.622 -17.962 1.00 42.27  ? 125 VAL C CG1 1 
ATOM   7177  C CG2 . VAL C 1 125 ? 57.918  -28.385 -16.418 1.00 39.18  ? 125 VAL C CG2 1 
ATOM   7178  N N   . ALA C 1 126 ? 61.208  -27.362 -16.925 1.00 45.65  ? 126 ALA C N   1 
ATOM   7179  C CA  . ALA C 1 126 ? 62.305  -27.871 -16.115 1.00 41.82  ? 126 ALA C CA  1 
ATOM   7180  C C   . ALA C 1 126 ? 61.892  -29.181 -15.461 1.00 39.45  ? 126 ALA C C   1 
ATOM   7181  O O   . ALA C 1 126 ? 60.791  -29.300 -14.918 1.00 40.00  ? 126 ALA C O   1 
ATOM   7182  C CB  . ALA C 1 126 ? 62.691  -26.838 -15.054 1.00 39.26  ? 126 ALA C CB  1 
ATOM   7183  N N   . ALA C 1 127 ? 62.756  -30.184 -15.562 1.00 46.89  ? 127 ALA C N   1 
ATOM   7184  C CA  . ALA C 1 127 ? 62.412  -31.492 -15.018 1.00 42.72  ? 127 ALA C CA  1 
ATOM   7185  C C   . ALA C 1 127 ? 62.113  -31.373 -13.529 1.00 37.48  ? 127 ALA C C   1 
ATOM   7186  O O   . ALA C 1 127 ? 62.764  -30.607 -12.811 1.00 32.89  ? 127 ALA C O   1 
ATOM   7187  C CB  . ALA C 1 127 ? 63.549  -32.486 -15.261 1.00 31.05  ? 127 ALA C CB  1 
ATOM   7188  N N   . LEU C 1 128 ? 61.103  -32.107 -13.072 1.00 34.77  ? 128 LEU C N   1 
ATOM   7189  C CA  . LEU C 1 128 ? 60.860  -32.184 -11.637 1.00 38.73  ? 128 LEU C CA  1 
ATOM   7190  C C   . LEU C 1 128 ? 62.119  -32.703 -10.952 1.00 33.16  ? 128 LEU C C   1 
ATOM   7191  O O   . LEU C 1 128 ? 62.638  -33.764 -11.311 1.00 29.43  ? 128 LEU C O   1 
ATOM   7192  C CB  . LEU C 1 128 ? 59.661  -33.089 -11.340 1.00 37.59  ? 128 LEU C CB  1 
ATOM   7193  C CG  . LEU C 1 128 ? 59.063  -33.012 -9.929  1.00 34.39  ? 128 LEU C CG  1 
ATOM   7194  C CD1 . LEU C 1 128 ? 58.361  -31.679 -9.713  1.00 35.39  ? 128 LEU C CD1 1 
ATOM   7195  C CD2 . LEU C 1 128 ? 58.113  -34.164 -9.662  1.00 33.65  ? 128 LEU C CD2 1 
ATOM   7196  N N   . ASP C 1 129 ? 62.648  -31.925 -10.013 1.00 33.66  ? 129 ASP C N   1 
ATOM   7197  C CA  . ASP C 1 129 ? 63.824  -32.364 -9.270  1.00 33.01  ? 129 ASP C CA  1 
ATOM   7198  C C   . ASP C 1 129 ? 63.537  -33.705 -8.599  1.00 32.62  ? 129 ASP C C   1 
ATOM   7199  O O   . ASP C 1 129 ? 62.438  -33.941 -8.095  1.00 27.84  ? 129 ASP C O   1 
ATOM   7200  C CB  . ASP C 1 129 ? 64.218  -31.313 -8.227  1.00 31.00  ? 129 ASP C CB  1 
ATOM   7201  C CG  . ASP C 1 129 ? 65.634  -31.517 -7.697  1.00 33.35  ? 129 ASP C CG  1 
ATOM   7202  O OD1 . ASP C 1 129 ? 66.391  -32.304 -8.306  1.00 34.77  ? 129 ASP C OD1 1 
ATOM   7203  O OD2 . ASP C 1 129 ? 65.981  -30.898 -6.669  1.00 33.40  ? 129 ASP C OD2 1 
ATOM   7204  N N   . GLY C 1 130 ? 64.526  -34.591 -8.589  1.00 33.26  ? 130 GLY C N   1 
ATOM   7205  C CA  . GLY C 1 130 ? 64.240  -35.954 -8.161  1.00 27.55  ? 130 GLY C CA  1 
ATOM   7206  C C   . GLY C 1 130 ? 63.256  -36.678 -9.058  1.00 28.71  ? 130 GLY C C   1 
ATOM   7207  O O   . GLY C 1 130 ? 62.421  -37.450 -8.564  1.00 26.03  ? 130 GLY C O   1 
ATOM   7208  N N   . TYR C 1 131 ? 63.339  -36.444 -10.377 1.00 31.79  ? 131 TYR C N   1 
ATOM   7209  C CA  . TYR C 1 131 ? 62.393  -37.006 -11.346 1.00 31.64  ? 131 TYR C CA  1 
ATOM   7210  C C   . TYR C 1 131 ? 62.179  -38.517 -11.161 1.00 30.07  ? 131 TYR C C   1 
ATOM   7211  O O   . TYR C 1 131 ? 61.046  -38.979 -10.941 1.00 25.37  ? 131 TYR C O   1 
ATOM   7212  C CB  . TYR C 1 131 ? 62.887  -36.694 -12.764 1.00 27.64  ? 131 TYR C CB  1 
ATOM   7213  C CG  . TYR C 1 131 ? 62.037  -37.288 -13.876 1.00 30.35  ? 131 TYR C CG  1 
ATOM   7214  C CD1 . TYR C 1 131 ? 60.905  -36.629 -14.346 1.00 31.38  ? 131 TYR C CD1 1 
ATOM   7215  C CD2 . TYR C 1 131 ? 62.377  -38.501 -14.463 1.00 33.08  ? 131 TYR C CD2 1 
ATOM   7216  C CE1 . TYR C 1 131 ? 60.135  -37.167 -15.359 1.00 34.48  ? 131 TYR C CE1 1 
ATOM   7217  C CE2 . TYR C 1 131 ? 61.615  -39.048 -15.471 1.00 35.46  ? 131 TYR C CE2 1 
ATOM   7218  C CZ  . TYR C 1 131 ? 60.495  -38.375 -15.921 1.00 39.42  ? 131 TYR C CZ  1 
ATOM   7219  O OH  . TYR C 1 131 ? 59.737  -38.925 -16.930 1.00 38.40  ? 131 TYR C OH  1 
ATOM   7220  N N   . GLU C 1 132 ? 63.267  -39.298 -11.238 1.00 24.88  ? 132 GLU C N   1 
ATOM   7221  C CA  . GLU C 1 132 ? 63.164  -40.765 -11.195 1.00 28.16  ? 132 GLU C CA  1 
ATOM   7222  C C   . GLU C 1 132 ? 62.562  -41.265 -9.890  1.00 25.45  ? 132 GLU C C   1 
ATOM   7223  O O   . GLU C 1 132 ? 61.818  -42.253 -9.889  1.00 24.81  ? 132 GLU C O   1 
ATOM   7224  C CB  . GLU C 1 132 ? 64.538  -41.420 -11.395 1.00 25.52  ? 132 GLU C CB  1 
ATOM   7225  C CG  . GLU C 1 132 ? 65.255  -41.062 -12.697 1.00 29.91  ? 132 GLU C CG  1 
ATOM   7226  C CD  . GLU C 1 132 ? 64.552  -41.579 -13.958 1.00 33.98  ? 132 GLU C CD  1 
ATOM   7227  O OE1 . GLU C 1 132 ? 63.477  -42.220 -13.855 1.00 32.71  ? 132 GLU C OE1 1 
ATOM   7228  O OE2 . GLU C 1 132 ? 65.087  -41.341 -15.066 1.00 40.08  ? 132 GLU C OE2 1 
ATOM   7229  N N   . PHE C 1 133 ? 62.901  -40.629 -8.767  1.00 20.81  ? 133 PHE C N   1 
ATOM   7230  C CA  . PHE C 1 133 ? 62.345  -41.054 -7.482  1.00 22.10  ? 133 PHE C CA  1 
ATOM   7231  C C   . PHE C 1 133 ? 60.831  -40.865 -7.439  1.00 22.36  ? 133 PHE C C   1 
ATOM   7232  O O   . PHE C 1 133 ? 60.097  -41.713 -6.921  1.00 22.78  ? 133 PHE C O   1 
ATOM   7233  C CB  . PHE C 1 133 ? 63.019  -40.272 -6.351  1.00 24.43  ? 133 PHE C CB  1 
ATOM   7234  C CG  . PHE C 1 133 ? 62.613  -40.714 -4.961  1.00 24.09  ? 133 PHE C CG  1 
ATOM   7235  C CD1 . PHE C 1 133 ? 63.139  -41.872 -4.399  1.00 25.48  ? 133 PHE C CD1 1 
ATOM   7236  C CD2 . PHE C 1 133 ? 61.743  -39.948 -4.207  1.00 18.54  ? 133 PHE C CD2 1 
ATOM   7237  C CE1 . PHE C 1 133 ? 62.786  -42.275 -3.096  1.00 21.71  ? 133 PHE C CE1 1 
ATOM   7238  C CE2 . PHE C 1 133 ? 61.387  -40.332 -2.915  1.00 23.16  ? 133 PHE C CE2 1 
ATOM   7239  C CZ  . PHE C 1 133 ? 61.915  -41.503 -2.363  1.00 25.85  ? 133 PHE C CZ  1 
ATOM   7240  N N   . ALA C 1 134 ? 60.350  -39.743 -7.958  1.00 27.88  ? 134 ALA C N   1 
ATOM   7241  C CA  . ALA C 1 134 ? 58.915  -39.545 -8.113  1.00 26.81  ? 134 ALA C CA  1 
ATOM   7242  C C   . ALA C 1 134 ? 58.297  -40.605 -9.023  1.00 23.23  ? 134 ALA C C   1 
ATOM   7243  O O   . ALA C 1 134 ? 57.208  -41.116 -8.740  1.00 26.63  ? 134 ALA C O   1 
ATOM   7244  C CB  . ALA C 1 134 ? 58.660  -38.151 -8.676  1.00 26.26  ? 134 ALA C CB  1 
ATOM   7245  N N   . MET C 1 135 ? 58.982  -40.953 -10.118 1.00 26.09  ? 135 MET C N   1 
ATOM   7246  C CA  . MET C 1 135 ? 58.432  -41.891 -11.097 1.00 23.38  ? 135 MET C CA  1 
ATOM   7247  C C   . MET C 1 135 ? 58.159  -43.266 -10.509 1.00 28.15  ? 135 MET C C   1 
ATOM   7248  O O   . MET C 1 135 ? 57.297  -43.989 -11.026 1.00 32.24  ? 135 MET C O   1 
ATOM   7249  C CB  . MET C 1 135 ? 59.374  -42.013 -12.289 1.00 26.86  ? 135 MET C CB  1 
ATOM   7250  C CG  . MET C 1 135 ? 59.371  -40.804 -13.278 1.00 29.87  ? 135 MET C CG  1 
ATOM   7251  S SD  . MET C 1 135 ? 57.759  -40.273 -13.936 1.00 32.09  ? 135 MET C SD  1 
ATOM   7252  C CE  . MET C 1 135 ? 57.719  -41.194 -15.479 1.00 35.14  ? 135 MET C CE  1 
ATOM   7253  N N   . GLN C 1 136 ? 58.871  -43.654 -9.454  1.00 25.39  ? 136 GLN C N   1 
ATOM   7254  C CA  . GLN C 1 136 ? 58.573  -44.878 -8.729  1.00 24.47  ? 136 GLN C CA  1 
ATOM   7255  C C   . GLN C 1 136 ? 57.697  -44.612 -7.524  1.00 21.28  ? 136 GLN C C   1 
ATOM   7256  O O   . GLN C 1 136 ? 57.580  -45.482 -6.656  1.00 25.03  ? 136 GLN C O   1 
ATOM   7257  C CB  . GLN C 1 136 ? 59.869  -45.579 -8.293  1.00 25.52  ? 136 GLN C CB  1 
ATOM   7258  C CG  . GLN C 1 136 ? 60.878  -45.778 -9.411  1.00 24.35  ? 136 GLN C CG  1 
ATOM   7259  C CD  . GLN C 1 136 ? 60.363  -46.693 -10.516 1.00 25.33  ? 136 GLN C CD  1 
ATOM   7260  O OE1 . GLN C 1 136 ? 59.907  -47.790 -10.245 1.00 29.70  ? 136 GLN C OE1 1 
ATOM   7261  N NE2 . GLN C 1 136 ? 60.429  -46.238 -11.761 1.00 25.22  ? 136 GLN C NE2 1 
ATOM   7262  N N   . ASN C 1 137 ? 57.107  -43.418 -7.443  1.00 22.03  ? 137 ASN C N   1 
ATOM   7263  C CA  . ASN C 1 137 ? 56.289  -43.012 -6.300  1.00 32.12  ? 137 ASN C CA  1 
ATOM   7264  C C   . ASN C 1 137 ? 57.045  -43.192 -4.985  1.00 26.12  ? 137 ASN C C   1 
ATOM   7265  O O   . ASN C 1 137 ? 56.536  -43.766 -4.021  1.00 26.82  ? 137 ASN C O   1 
ATOM   7266  C CB  . ASN C 1 137 ? 54.963  -43.782 -6.271  1.00 31.12  ? 137 ASN C CB  1 
ATOM   7267  C CG  . ASN C 1 137 ? 54.026  -43.347 -7.366  1.00 28.17  ? 137 ASN C CG  1 
ATOM   7268  O OD1 . ASN C 1 137 ? 53.658  -42.166 -7.461  1.00 32.81  ? 137 ASN C OD1 1 
ATOM   7269  N ND2 . ASN C 1 137 ? 53.635  -44.289 -8.206  1.00 29.31  ? 137 ASN C ND2 1 
ATOM   7270  N N   . GLY C 1 138 ? 58.282  -42.700 -4.962  1.00 20.45  ? 138 GLY C N   1 
ATOM   7271  C CA  . GLY C 1 138 ? 59.085  -42.820 -3.762  1.00 24.71  ? 138 GLY C CA  1 
ATOM   7272  C C   . GLY C 1 138 ? 58.516  -42.061 -2.583  1.00 24.94  ? 138 GLY C C   1 
ATOM   7273  O O   . GLY C 1 138 ? 58.731  -42.447 -1.431  1.00 25.10  ? 138 GLY C O   1 
ATOM   7274  N N   . ILE C 1 139 ? 57.786  -40.972 -2.844  1.00 29.84  ? 139 ILE C N   1 
ATOM   7275  C CA  . ILE C 1 139 ? 57.220  -40.209 -1.744  1.00 27.61  ? 139 ILE C CA  1 
ATOM   7276  C C   . ILE C 1 139 ? 56.108  -41.001 -1.055  1.00 32.76  ? 139 ILE C C   1 
ATOM   7277  O O   . ILE C 1 139 ? 55.820  -40.767 0.126   1.00 30.24  ? 139 ILE C O   1 
ATOM   7278  C CB  . ILE C 1 139 ? 56.762  -38.821 -2.248  1.00 34.24  ? 139 ILE C CB  1 
ATOM   7279  C CG1 . ILE C 1 139 ? 55.473  -38.911 -3.055  1.00 33.07  ? 139 ILE C CG1 1 
ATOM   7280  C CG2 . ILE C 1 139 ? 57.875  -38.138 -3.079  1.00 27.90  ? 139 ILE C CG2 1 
ATOM   7281  C CD1 . ILE C 1 139 ? 54.179  -38.887 -2.208  1.00 40.40  ? 139 ILE C CD1 1 
ATOM   7282  N N   . ASP C 1 140 ? 55.469  -41.937 -1.768  1.00 35.27  ? 140 ASP C N   1 
ATOM   7283  C CA  . ASP C 1 140 ? 54.513  -42.825 -1.116  1.00 34.91  ? 140 ASP C CA  1 
ATOM   7284  C C   . ASP C 1 140 ? 55.187  -43.637 -0.023  1.00 32.74  ? 140 ASP C C   1 
ATOM   7285  O O   . ASP C 1 140 ? 54.625  -43.817 1.064   1.00 32.85  ? 140 ASP C O   1 
ATOM   7286  C CB  . ASP C 1 140 ? 53.873  -43.755 -2.142  1.00 35.92  ? 140 ASP C CB  1 
ATOM   7287  C CG  . ASP C 1 140 ? 52.473  -43.337 -2.513  1.00 47.38  ? 140 ASP C CG  1 
ATOM   7288  O OD1 . ASP C 1 140 ? 51.673  -43.064 -1.589  1.00 58.17  ? 140 ASP C OD1 1 
ATOM   7289  O OD2 . ASP C 1 140 ? 52.170  -43.280 -3.730  1.00 50.21  ? 140 ASP C OD2 1 
ATOM   7290  N N   . LEU C 1 141 ? 56.386  -44.149 -0.311  1.00 29.18  ? 141 LEU C N   1 
ATOM   7291  C CA  . LEU C 1 141 ? 57.223  -44.791 0.698   1.00 30.74  ? 141 LEU C CA  1 
ATOM   7292  C C   . LEU C 1 141 ? 57.425  -43.892 1.909   1.00 26.13  ? 141 LEU C C   1 
ATOM   7293  O O   . LEU C 1 141 ? 57.137  -44.280 3.044   1.00 29.49  ? 141 LEU C O   1 
ATOM   7294  C CB  . LEU C 1 141 ? 58.573  -45.144 0.074   1.00 32.55  ? 141 LEU C CB  1 
ATOM   7295  C CG  . LEU C 1 141 ? 59.577  -45.948 0.898   1.00 31.40  ? 141 LEU C CG  1 
ATOM   7296  C CD1 . LEU C 1 141 ? 58.950  -47.223 1.416   1.00 23.70  ? 141 LEU C CD1 1 
ATOM   7297  C CD2 . LEU C 1 141 ? 60.783  -46.217 0.035   1.00 31.76  ? 141 LEU C CD2 1 
ATOM   7298  N N   . LEU C 1 142 ? 57.907  -42.674 1.674   1.00 27.96  ? 142 LEU C N   1 
ATOM   7299  C CA  . LEU C 1 142 ? 58.309  -41.776 2.750   1.00 27.68  ? 142 LEU C CA  1 
ATOM   7300  C C   . LEU C 1 142 ? 57.133  -41.323 3.599   1.00 27.96  ? 142 LEU C C   1 
ATOM   7301  O O   . LEU C 1 142 ? 57.286  -41.112 4.802   1.00 29.91  ? 142 LEU C O   1 
ATOM   7302  C CB  . LEU C 1 142 ? 59.014  -40.564 2.155   1.00 30.58  ? 142 LEU C CB  1 
ATOM   7303  C CG  . LEU C 1 142 ? 60.225  -40.912 1.295   1.00 26.29  ? 142 LEU C CG  1 
ATOM   7304  C CD1 . LEU C 1 142 ? 60.990  -39.668 0.964   1.00 22.21  ? 142 LEU C CD1 1 
ATOM   7305  C CD2 . LEU C 1 142 ? 61.076  -41.840 2.142   1.00 28.77  ? 142 LEU C CD2 1 
ATOM   7306  N N   . ASN C 1 143 ? 55.964  -41.152 3.003   1.00 28.23  ? 143 ASN C N   1 
ATOM   7307  C CA  . ASN C 1 143 ? 54.823  -40.657 3.746   1.00 29.75  ? 143 ASN C CA  1 
ATOM   7308  C C   . ASN C 1 143 ? 54.090  -41.747 4.522   1.00 33.34  ? 143 ASN C C   1 
ATOM   7309  O O   . ASN C 1 143 ? 52.931  -41.544 4.889   1.00 37.25  ? 143 ASN C O   1 
ATOM   7310  C CB  . ASN C 1 143 ? 53.863  -39.936 2.801   1.00 24.30  ? 143 ASN C CB  1 
ATOM   7311  C CG  . ASN C 1 143 ? 54.353  -38.563 2.443   1.00 28.81  ? 143 ASN C CG  1 
ATOM   7312  O OD1 . ASN C 1 143 ? 55.260  -38.048 3.089   1.00 26.45  ? 143 ASN C OD1 1 
ATOM   7313  N ND2 . ASN C 1 143 ? 53.795  -37.973 1.389   1.00 29.10  ? 143 ASN C ND2 1 
ATOM   7314  N N   . MET C 1 144 ? 54.709  -42.895 4.789   1.00 33.68  ? 144 MET C N   1 
ATOM   7315  C CA  . MET C 1 144 ? 54.093  -43.910 5.645   1.00 35.43  ? 144 MET C CA  1 
ATOM   7316  C C   . MET C 1 144 ? 54.660  -43.797 7.054   1.00 31.76  ? 144 MET C C   1 
ATOM   7317  O O   . MET C 1 144 ? 55.883  -43.761 7.236   1.00 31.77  ? 144 MET C O   1 
ATOM   7318  C CB  . MET C 1 144 ? 54.306  -45.323 5.086   1.00 30.93  ? 144 MET C CB  1 
ATOM   7319  C CG  . MET C 1 144 ? 53.849  -45.471 3.656   1.00 31.41  ? 144 MET C CG  1 
ATOM   7320  S SD  . MET C 1 144 ? 54.249  -47.080 2.959   1.00 39.08  ? 144 MET C SD  1 
ATOM   7321  C CE  . MET C 1 144 ? 53.449  -48.167 4.143   1.00 37.79  ? 144 MET C CE  1 
ATOM   7322  N N   . LYS C 1 145 ? 53.770  -43.714 8.044   1.00 30.01  ? 145 LYS C N   1 
ATOM   7323  C CA  . LYS C 1 145 ? 54.221  -43.669 9.431   1.00 29.85  ? 145 LYS C CA  1 
ATOM   7324  C C   . LYS C 1 145 ? 55.093  -44.869 9.762   1.00 29.46  ? 145 LYS C C   1 
ATOM   7325  O O   . LYS C 1 145 ? 56.077  -44.743 10.509  1.00 22.80  ? 145 LYS C O   1 
ATOM   7326  C CB  . LYS C 1 145 ? 53.024  -43.597 10.380  1.00 32.36  ? 145 LYS C CB  1 
ATOM   7327  C CG  . LYS C 1 145 ? 52.309  -42.250 10.324  1.00 35.48  ? 145 LYS C CG  1 
ATOM   7328  C CD  . LYS C 1 145 ? 51.114  -42.186 11.264  1.00 38.75  ? 145 LYS C CD  1 
ATOM   7329  C CE  . LYS C 1 145 ? 50.104  -41.146 10.780  1.00 38.44  ? 145 LYS C CE  1 
ATOM   7330  N NZ  . LYS C 1 145 ? 49.709  -41.375 9.363   1.00 32.60  ? 145 LYS C NZ  1 
ATOM   7331  N N   . SER C 1 146 ? 54.763  -46.043 9.197   1.00 23.89  ? 146 SER C N   1 
ATOM   7332  C CA  . SER C 1 146 ? 55.598  -47.215 9.434   1.00 25.42  ? 146 SER C CA  1 
ATOM   7333  C C   . SER C 1 146 ? 56.997  -47.033 8.855   1.00 23.70  ? 146 SER C C   1 
ATOM   7334  O O   . SER C 1 146 ? 57.968  -47.532 9.428   1.00 25.91  ? 146 SER C O   1 
ATOM   7335  C CB  . SER C 1 146 ? 54.946  -48.476 8.860   1.00 26.13  ? 146 SER C CB  1 
ATOM   7336  O OG  . SER C 1 146 ? 54.834  -48.401 7.458   1.00 27.39  ? 146 SER C OG  1 
ATOM   7337  N N   . THR C 1 147 ? 57.130  -46.322 7.735   1.00 22.15  ? 147 THR C N   1 
ATOM   7338  C CA  . THR C 1 147 ? 58.460  -46.084 7.194   1.00 22.20  ? 147 THR C CA  1 
ATOM   7339  C C   . THR C 1 147 ? 59.259  -45.173 8.113   1.00 25.66  ? 147 THR C C   1 
ATOM   7340  O O   . THR C 1 147 ? 60.471  -45.376 8.302   1.00 17.27  ? 147 THR C O   1 
ATOM   7341  C CB  . THR C 1 147 ? 58.381  -45.491 5.787   1.00 23.94  ? 147 THR C CB  1 
ATOM   7342  O OG1 . THR C 1 147 ? 57.654  -46.376 4.925   1.00 26.38  ? 147 THR C OG1 1 
ATOM   7343  C CG2 . THR C 1 147 ? 59.782  -45.288 5.209   1.00 23.04  ? 147 THR C CG2 1 
ATOM   7344  N N   . PHE C 1 148 ? 58.602  -44.168 8.713   1.00 21.61  ? 148 PHE C N   1 
ATOM   7345  C CA  . PHE C 1 148 ? 59.369  -43.263 9.559   1.00 25.16  ? 148 PHE C CA  1 
ATOM   7346  C C   . PHE C 1 148 ? 59.904  -43.998 10.776  1.00 22.82  ? 148 PHE C C   1 
ATOM   7347  O O   . PHE C 1 148 ? 61.075  -43.839 11.139  1.00 22.77  ? 148 PHE C O   1 
ATOM   7348  C CB  . PHE C 1 148 ? 58.543  -42.055 10.000  1.00 27.29  ? 148 PHE C CB  1 
ATOM   7349  C CG  . PHE C 1 148 ? 59.216  -41.246 11.077  1.00 27.07  ? 148 PHE C CG  1 
ATOM   7350  C CD1 . PHE C 1 148 ? 60.183  -40.310 10.761  1.00 25.86  ? 148 PHE C CD1 1 
ATOM   7351  C CD2 . PHE C 1 148 ? 58.922  -41.467 12.418  1.00 28.63  ? 148 PHE C CD2 1 
ATOM   7352  C CE1 . PHE C 1 148 ? 60.820  -39.582 11.767  1.00 24.70  ? 148 PHE C CE1 1 
ATOM   7353  C CE2 . PHE C 1 148 ? 59.548  -40.736 13.410  1.00 25.73  ? 148 PHE C CE2 1 
ATOM   7354  C CZ  . PHE C 1 148 ? 60.502  -39.796 13.073  1.00 21.37  ? 148 PHE C CZ  1 
ATOM   7355  N N   . ARG C 1 149 ? 59.074  -44.824 11.399  1.00 18.84  ? 149 ARG C N   1 
ATOM   7356  C CA  . ARG C 1 149 ? 59.544  -45.595 12.537  1.00 20.18  ? 149 ARG C CA  1 
ATOM   7357  C C   . ARG C 1 149 ? 60.709  -46.482 12.136  1.00 19.66  ? 149 ARG C C   1 
ATOM   7358  O O   . ARG C 1 149 ? 61.664  -46.644 12.898  1.00 19.06  ? 149 ARG C O   1 
ATOM   7359  C CB  . ARG C 1 149 ? 58.405  -46.444 13.108  1.00 21.85  ? 149 ARG C CB  1 
ATOM   7360  C CG  . ARG C 1 149 ? 57.401  -45.664 13.931  1.00 24.35  ? 149 ARG C CG  1 
ATOM   7361  C CD  . ARG C 1 149 ? 56.587  -46.608 14.787  1.00 24.99  ? 149 ARG C CD  1 
ATOM   7362  N NE  . ARG C 1 149 ? 57.428  -47.203 15.809  1.00 31.36  ? 149 ARG C NE  1 
ATOM   7363  C CZ  . ARG C 1 149 ? 57.753  -46.613 16.952  1.00 27.85  ? 149 ARG C CZ  1 
ATOM   7364  N NH1 . ARG C 1 149 ? 57.258  -45.433 17.288  1.00 26.63  ? 149 ARG C NH1 1 
ATOM   7365  N NH2 . ARG C 1 149 ? 58.608  -47.216 17.770  1.00 23.98  ? 149 ARG C NH2 1 
ATOM   7366  N N   . ARG C 1 150 ? 60.636  -47.075 10.947  1.00 17.32  ? 150 ARG C N   1 
ATOM   7367  C CA  . ARG C 1 150 ? 61.696  -47.967 10.501  1.00 22.74  ? 150 ARG C CA  1 
ATOM   7368  C C   . ARG C 1 150 ? 62.977  -47.197 10.259  1.00 18.81  ? 150 ARG C C   1 
ATOM   7369  O O   . ARG C 1 150 ? 64.017  -47.518 10.834  1.00 24.29  ? 150 ARG C O   1 
ATOM   7370  C CB  . ARG C 1 150 ? 61.258  -48.718 9.247   1.00 18.12  ? 150 ARG C CB  1 
ATOM   7371  C CG  . ARG C 1 150 ? 60.350  -49.888 9.569   1.00 26.73  ? 150 ARG C CG  1 
ATOM   7372  C CD  . ARG C 1 150 ? 59.359  -50.190 8.435   1.00 24.77  ? 150 ARG C CD  1 
ATOM   7373  N NE  . ARG C 1 150 ? 58.729  -51.481 8.673   1.00 27.25  ? 150 ARG C NE  1 
ATOM   7374  C CZ  . ARG C 1 150 ? 57.924  -52.096 7.818   1.00 28.78  ? 150 ARG C CZ  1 
ATOM   7375  N NH1 . ARG C 1 150 ? 57.588  -51.544 6.662   1.00 25.98  ? 150 ARG C NH1 1 
ATOM   7376  N NH2 . ARG C 1 150 ? 57.450  -53.296 8.128   1.00 23.26  ? 150 ARG C NH2 1 
ATOM   7377  N N   . LEU C 1 151 ? 62.901  -46.132 9.463   1.00 21.12  ? 151 LEU C N   1 
ATOM   7378  C CA  . LEU C 1 151 ? 64.077  -45.309 9.198   1.00 24.17  ? 151 LEU C CA  1 
ATOM   7379  C C   . LEU C 1 151 ? 64.627  -44.680 10.482  1.00 26.93  ? 151 LEU C C   1 
ATOM   7380  O O   . LEU C 1 151 ? 65.848  -44.656 10.692  1.00 26.82  ? 151 LEU C O   1 
ATOM   7381  C CB  . LEU C 1 151 ? 63.734  -44.231 8.159   1.00 23.47  ? 151 LEU C CB  1 
ATOM   7382  C CG  . LEU C 1 151 ? 63.375  -44.737 6.746   1.00 25.93  ? 151 LEU C CG  1 
ATOM   7383  C CD1 . LEU C 1 151 ? 62.998  -43.570 5.821   1.00 24.74  ? 151 LEU C CD1 1 
ATOM   7384  C CD2 . LEU C 1 151 ? 64.510  -45.561 6.118   1.00 24.01  ? 151 LEU C CD2 1 
ATOM   7385  N N   . ALA C 1 152 ? 63.752  -44.184 11.362  1.00 20.45  ? 152 ALA C N   1 
ATOM   7386  C CA  . ALA C 1 152 ? 64.249  -43.550 12.580  1.00 23.30  ? 152 ALA C CA  1 
ATOM   7387  C C   . ALA C 1 152 ? 64.935  -44.572 13.470  1.00 27.75  ? 152 ALA C C   1 
ATOM   7388  O O   . ALA C 1 152 ? 66.031  -44.319 13.986  1.00 19.52  ? 152 ALA C O   1 
ATOM   7389  C CB  . ALA C 1 152 ? 63.119  -42.851 13.340  1.00 21.77  ? 152 ALA C CB  1 
ATOM   7390  N N   . ALA C 1 153 ? 64.312  -45.744 13.642  1.00 25.60  ? 153 ALA C N   1 
ATOM   7391  C CA  . ALA C 1 153 ? 64.939  -46.790 14.441  1.00 25.07  ? 153 ALA C CA  1 
ATOM   7392  C C   . ALA C 1 153 ? 66.309  -47.157 13.874  1.00 23.38  ? 153 ALA C C   1 
ATOM   7393  O O   . ALA C 1 153 ? 67.230  -47.474 14.626  1.00 26.79  ? 153 ALA C O   1 
ATOM   7394  C CB  . ALA C 1 153 ? 64.027  -48.016 14.506  1.00 20.18  ? 153 ALA C CB  1 
ATOM   7395  N N   . GLY C 1 154 ? 66.450  -47.103 12.544  1.00 28.08  ? 154 GLY C N   1 
ATOM   7396  C CA  . GLY C 1 154 ? 67.704  -47.460 11.897  1.00 28.26  ? 154 GLY C CA  1 
ATOM   7397  C C   . GLY C 1 154 ? 68.820  -46.491 12.221  1.00 22.98  ? 154 GLY C C   1 
ATOM   7398  O O   . GLY C 1 154 ? 69.926  -46.893 12.574  1.00 26.56  ? 154 GLY C O   1 
ATOM   7399  N N   . LEU C 1 155 ? 68.545  -45.203 12.110  1.00 28.30  ? 155 LEU C N   1 
ATOM   7400  C CA  . LEU C 1 155 ? 69.414  -44.212 12.710  1.00 30.32  ? 155 LEU C CA  1 
ATOM   7401  C C   . LEU C 1 155 ? 69.196  -44.209 14.221  1.00 28.23  ? 155 LEU C C   1 
ATOM   7402  O O   . LEU C 1 155 ? 68.406  -44.971 14.766  1.00 33.71  ? 155 LEU C O   1 
ATOM   7403  C CB  . LEU C 1 155 ? 69.136  -42.845 12.110  1.00 33.03  ? 155 LEU C CB  1 
ATOM   7404  C CG  . LEU C 1 155 ? 69.522  -42.494 10.683  1.00 33.38  ? 155 LEU C CG  1 
ATOM   7405  C CD1 . LEU C 1 155 ? 69.056  -41.079 10.461  1.00 24.81  ? 155 LEU C CD1 1 
ATOM   7406  C CD2 . LEU C 1 155 ? 71.035  -42.575 10.496  1.00 30.56  ? 155 LEU C CD2 1 
ATOM   7407  N N   . GLY C 1 156 ? 69.876  -43.347 14.933  1.00 38.31  ? 156 GLY C N   1 
ATOM   7408  C CA  . GLY C 1 156 ? 69.561  -43.333 16.347  1.00 29.68  ? 156 GLY C CA  1 
ATOM   7409  C C   . GLY C 1 156 ? 68.441  -42.379 16.676  1.00 31.31  ? 156 GLY C C   1 
ATOM   7410  O O   . GLY C 1 156 ? 68.271  -42.012 17.847  1.00 36.36  ? 156 GLY C O   1 
ATOM   7411  N N   . THR C 1 157 ? 67.651  -42.000 15.664  1.00 28.29  ? 157 THR C N   1 
ATOM   7412  C CA  . THR C 1 157 ? 66.715  -40.888 15.807  1.00 29.78  ? 157 THR C CA  1 
ATOM   7413  C C   . THR C 1 157 ? 65.756  -41.135 16.973  1.00 30.16  ? 157 THR C C   1 
ATOM   7414  O O   . THR C 1 157 ? 65.104  -42.182 17.021  1.00 25.12  ? 157 THR C O   1 
ATOM   7415  C CB  . THR C 1 157 ? 65.936  -40.666 14.510  1.00 26.54  ? 157 THR C CB  1 
ATOM   7416  O OG1 . THR C 1 157 ? 66.831  -40.201 13.485  1.00 30.53  ? 157 THR C OG1 1 
ATOM   7417  C CG2 . THR C 1 157 ? 64.850  -39.615 14.717  1.00 23.42  ? 157 THR C CG2 1 
ATOM   7418  N N   . PRO C 1 158 ? 65.648  -40.206 17.920  1.00 31.69  ? 158 PRO C N   1 
ATOM   7419  C CA  . PRO C 1 158 ? 64.868  -40.472 19.135  1.00 31.48  ? 158 PRO C CA  1 
ATOM   7420  C C   . PRO C 1 158 ? 63.420  -40.750 18.785  1.00 30.85  ? 158 PRO C C   1 
ATOM   7421  O O   . PRO C 1 158 ? 62.790  -39.998 18.044  1.00 28.73  ? 158 PRO C O   1 
ATOM   7422  C CB  . PRO C 1 158 ? 65.012  -39.181 19.946  1.00 30.40  ? 158 PRO C CB  1 
ATOM   7423  C CG  . PRO C 1 158 ? 66.174  -38.448 19.338  1.00 27.87  ? 158 PRO C CG  1 
ATOM   7424  C CD  . PRO C 1 158 ? 66.202  -38.844 17.891  1.00 29.85  ? 158 PRO C CD  1 
ATOM   7425  N N   . LEU C 1 159 ? 62.898  -41.837 19.331  1.00 28.28  ? 159 LEU C N   1 
ATOM   7426  C CA  . LEU C 1 159 ? 61.629  -42.398 18.909  1.00 30.36  ? 159 LEU C CA  1 
ATOM   7427  C C   . LEU C 1 159 ? 60.859  -42.861 20.132  1.00 26.59  ? 159 LEU C C   1 
ATOM   7428  O O   . LEU C 1 159 ? 61.449  -43.428 21.049  1.00 30.33  ? 159 LEU C O   1 
ATOM   7429  C CB  . LEU C 1 159 ? 61.871  -43.583 17.969  1.00 26.58  ? 159 LEU C CB  1 
ATOM   7430  C CG  . LEU C 1 159 ? 60.740  -44.032 17.067  1.00 26.87  ? 159 LEU C CG  1 
ATOM   7431  C CD1 . LEU C 1 159 ? 60.437  -42.957 16.060  1.00 32.25  ? 159 LEU C CD1 1 
ATOM   7432  C CD2 . LEU C 1 159 ? 61.133  -45.316 16.382  1.00 28.97  ? 159 LEU C CD2 1 
ATOM   7433  N N   . THR C 1 160 ? 59.551  -42.636 20.155  1.00 26.57  ? 160 THR C N   1 
ATOM   7434  C CA  . THR C 1 160 ? 58.763  -43.268 21.199  1.00 30.56  ? 160 THR C CA  1 
ATOM   7435  C C   . THR C 1 160 ? 58.710  -44.770 20.973  1.00 28.47  ? 160 THR C C   1 
ATOM   7436  O O   . THR C 1 160 ? 58.837  -45.260 19.843  1.00 26.76  ? 160 THR C O   1 
ATOM   7437  C CB  . THR C 1 160 ? 57.330  -42.728 21.252  1.00 38.00  ? 160 THR C CB  1 
ATOM   7438  O OG1 . THR C 1 160 ? 56.652  -43.007 20.008  1.00 31.64  ? 160 THR C OG1 1 
ATOM   7439  C CG2 . THR C 1 160 ? 57.327  -41.225 21.583  1.00 32.41  ? 160 THR C CG2 1 
ATOM   7440  N N   . ASP C 1 161 ? 58.515  -45.499 22.069  1.00 28.65  ? 161 ASP C N   1 
ATOM   7441  C CA  . ASP C 1 161 ? 58.291  -46.929 21.977  1.00 30.19  ? 161 ASP C CA  1 
ATOM   7442  C C   . ASP C 1 161 ? 57.008  -47.177 21.221  1.00 26.70  ? 161 ASP C C   1 
ATOM   7443  O O   . ASP C 1 161 ? 56.006  -46.487 21.418  1.00 27.49  ? 161 ASP C O   1 
ATOM   7444  C CB  . ASP C 1 161 ? 58.206  -47.548 23.360  1.00 29.90  ? 161 ASP C CB  1 
ATOM   7445  C CG  . ASP C 1 161 ? 59.556  -47.943 23.880  1.00 36.82  ? 161 ASP C CG  1 
ATOM   7446  O OD1 . ASP C 1 161 ? 60.538  -47.216 23.581  1.00 31.80  ? 161 ASP C OD1 1 
ATOM   7447  O OD2 . ASP C 1 161 ? 59.635  -48.971 24.585  1.00 47.58  ? 161 ASP C OD2 1 
ATOM   7448  N N   . GLY C 1 162 ? 57.049  -48.151 20.341  1.00 24.79  ? 162 GLY C N   1 
ATOM   7449  C CA  . GLY C 1 162 ? 55.894  -48.428 19.523  1.00 25.99  ? 162 GLY C CA  1 
ATOM   7450  C C   . GLY C 1 162 ? 56.210  -49.614 18.659  1.00 27.95  ? 162 GLY C C   1 
ATOM   7451  O O   . GLY C 1 162 ? 57.335  -50.129 18.656  1.00 30.75  ? 162 GLY C O   1 
ATOM   7452  N N   . VAL C 1 163 ? 55.185  -50.077 17.955  1.00 26.24  ? 163 VAL C N   1 
ATOM   7453  C CA  . VAL C 1 163 ? 55.322  -51.225 17.073  1.00 29.55  ? 163 VAL C CA  1 
ATOM   7454  C C   . VAL C 1 163 ? 54.520  -50.962 15.808  1.00 28.91  ? 163 VAL C C   1 
ATOM   7455  O O   . VAL C 1 163 ? 53.528  -50.227 15.813  1.00 31.15  ? 163 VAL C O   1 
ATOM   7456  C CB  . VAL C 1 163 ? 54.881  -52.557 17.753  1.00 34.76  ? 163 VAL C CB  1 
ATOM   7457  C CG1 . VAL C 1 163 ? 54.862  -52.442 19.281  1.00 28.39  ? 163 VAL C CG1 1 
ATOM   7458  C CG2 . VAL C 1 163 ? 53.530  -53.019 17.228  1.00 28.55  ? 163 VAL C CG2 1 
ATOM   7459  N N   . VAL C 1 164 ? 54.983  -51.546 14.708  1.00 25.87  ? 164 VAL C N   1 
ATOM   7460  C CA  . VAL C 1 164 ? 54.253  -51.530 13.449  1.00 27.75  ? 164 VAL C CA  1 
ATOM   7461  C C   . VAL C 1 164 ? 53.380  -52.783 13.463  1.00 26.68  ? 164 VAL C C   1 
ATOM   7462  O O   . VAL C 1 164 ? 53.833  -53.875 13.141  1.00 23.71  ? 164 VAL C O   1 
ATOM   7463  C CB  . VAL C 1 164 ? 55.205  -51.480 12.247  1.00 28.15  ? 164 VAL C CB  1 
ATOM   7464  C CG1 . VAL C 1 164 ? 54.462  -51.706 10.918  1.00 23.88  ? 164 VAL C CG1 1 
ATOM   7465  C CG2 . VAL C 1 164 ? 55.973  -50.145 12.239  1.00 22.00  ? 164 VAL C CG2 1 
ATOM   7466  N N   . ALA C 1 165 ? 52.124  -52.622 13.862  1.00 23.74  ? 165 ALA C N   1 
ATOM   7467  C CA  . ALA C 1 165 ? 51.221  -53.749 14.016  1.00 30.54  ? 165 ALA C CA  1 
ATOM   7468  C C   . ALA C 1 165 ? 50.716  -54.237 12.666  1.00 24.02  ? 165 ALA C C   1 
ATOM   7469  O O   . ALA C 1 165 ? 50.372  -53.435 11.795  1.00 27.30  ? 165 ALA C O   1 
ATOM   7470  C CB  . ALA C 1 165 ? 50.040  -53.354 14.905  1.00 29.44  ? 165 ALA C CB  1 
ATOM   7471  N N   . ARG C 1 166 ? 50.627  -55.564 12.513  1.00 26.92  ? 166 ARG C N   1 
ATOM   7472  C CA  . ARG C 1 166 ? 50.286  -56.193 11.235  1.00 28.49  ? 166 ARG C CA  1 
ATOM   7473  C C   . ARG C 1 166 ? 48.939  -56.908 11.234  1.00 36.37  ? 166 ARG C C   1 
ATOM   7474  O O   . ARG C 1 166 ? 48.535  -57.447 10.198  1.00 35.35  ? 166 ARG C O   1 
ATOM   7475  C CB  . ARG C 1 166 ? 51.374  -57.188 10.831  1.00 28.41  ? 166 ARG C CB  1 
ATOM   7476  C CG  . ARG C 1 166 ? 52.720  -56.544 10.648  1.00 27.20  ? 166 ARG C CG  1 
ATOM   7477  C CD  . ARG C 1 166 ? 53.834  -57.580 10.755  1.00 27.95  ? 166 ARG C CD  1 
ATOM   7478  N NE  . ARG C 1 166 ? 54.267  -57.805 12.130  1.00 31.72  ? 166 ARG C NE  1 
ATOM   7479  C CZ  . ARG C 1 166 ? 55.108  -58.766 12.486  1.00 34.56  ? 166 ARG C CZ  1 
ATOM   7480  N NH1 . ARG C 1 166 ? 55.599  -59.613 11.595  1.00 36.13  ? 166 ARG C NH1 1 
ATOM   7481  N NH2 . ARG C 1 166 ? 55.480  -58.869 13.756  1.00 28.95  ? 166 ARG C NH2 1 
ATOM   7482  N N   . GLY C 1 167 ? 48.230  -56.921 12.354  1.00 38.29  ? 167 GLY C N   1 
ATOM   7483  C CA  . GLY C 1 167 ? 46.886  -57.432 12.401  1.00 31.77  ? 167 GLY C CA  1 
ATOM   7484  C C   . GLY C 1 167 ? 46.307  -57.137 13.763  1.00 32.67  ? 167 GLY C C   1 
ATOM   7485  O O   . GLY C 1 167 ? 47.000  -56.634 14.656  1.00 31.45  ? 167 GLY C O   1 
ATOM   7486  N N   . PRO C 1 168 ? 45.031  -57.479 13.960  1.00 34.54  ? 168 PRO C N   1 
ATOM   7487  C CA  . PRO C 1 168 ? 44.382  -57.200 15.254  1.00 33.92  ? 168 PRO C CA  1 
ATOM   7488  C C   . PRO C 1 168 ? 45.078  -57.825 16.450  1.00 34.79  ? 168 PRO C C   1 
ATOM   7489  O O   . PRO C 1 168 ? 45.079  -57.222 17.534  1.00 35.77  ? 168 PRO C O   1 
ATOM   7490  C CB  . PRO C 1 168 ? 42.966  -57.765 15.074  1.00 35.19  ? 168 PRO C CB  1 
ATOM   7491  C CG  . PRO C 1 168 ? 42.990  -58.564 13.794  1.00 37.43  ? 168 PRO C CG  1 
ATOM   7492  C CD  . PRO C 1 168 ? 44.120  -58.085 12.969  1.00 34.73  ? 168 PRO C CD  1 
ATOM   7493  N N   . ALA C 1 169 ? 45.668  -59.014 16.302  1.00 35.40  ? 169 ALA C N   1 
ATOM   7494  C CA  . ALA C 1 169 ? 46.306  -59.651 17.454  1.00 37.51  ? 169 ALA C CA  1 
ATOM   7495  C C   . ALA C 1 169 ? 47.524  -58.862 17.906  1.00 34.18  ? 169 ALA C C   1 
ATOM   7496  O O   . ALA C 1 169 ? 47.773  -58.730 19.111  1.00 37.34  ? 169 ALA C O   1 
ATOM   7497  C CB  . ALA C 1 169 ? 46.691  -61.097 17.127  1.00 36.76  ? 169 ALA C CB  1 
ATOM   7498  N N   . GLU C 1 170 ? 48.282  -58.310 16.953  1.00 33.28  ? 170 GLU C N   1 
ATOM   7499  C CA  . GLU C 1 170 ? 49.448  -57.506 17.307  1.00 31.20  ? 170 GLU C CA  1 
ATOM   7500  C C   . GLU C 1 170 ? 49.035  -56.137 17.854  1.00 30.80  ? 170 GLU C C   1 
ATOM   7501  O O   . GLU C 1 170 ? 49.662  -55.620 18.785  1.00 31.30  ? 170 GLU C O   1 
ATOM   7502  C CB  . GLU C 1 170 ? 50.378  -57.377 16.097  1.00 26.09  ? 170 GLU C CB  1 
ATOM   7503  C CG  . GLU C 1 170 ? 51.825  -57.128 16.486  1.00 33.18  ? 170 GLU C CG  1 
ATOM   7504  C CD  . GLU C 1 170 ? 52.798  -57.181 15.322  1.00 32.79  ? 170 GLU C CD  1 
ATOM   7505  O OE1 . GLU C 1 170 ? 52.374  -57.178 14.143  1.00 30.67  ? 170 GLU C OE1 1 
ATOM   7506  O OE2 . GLU C 1 170 ? 54.009  -57.239 15.605  1.00 35.67  ? 170 GLU C OE2 1 
ATOM   7507  N N   . VAL C 1 171 ? 47.971  -55.542 17.313  1.00 30.43  ? 171 VAL C N   1 
ATOM   7508  C CA  . VAL C 1 171 ? 47.428  -54.333 17.929  1.00 32.10  ? 171 VAL C CA  1 
ATOM   7509  C C   . VAL C 1 171 ? 47.054  -54.600 19.382  1.00 33.09  ? 171 VAL C C   1 
ATOM   7510  O O   . VAL C 1 171 ? 47.419  -53.835 20.284  1.00 31.45  ? 171 VAL C O   1 
ATOM   7511  C CB  . VAL C 1 171 ? 46.226  -53.806 17.134  1.00 32.03  ? 171 VAL C CB  1 
ATOM   7512  C CG1 . VAL C 1 171 ? 45.724  -52.513 17.774  1.00 36.06  ? 171 VAL C CG1 1 
ATOM   7513  C CG2 . VAL C 1 171 ? 46.616  -53.575 15.697  1.00 29.93  ? 171 VAL C CG2 1 
ATOM   7514  N N   . ARG C 1 172 ? 46.329  -55.694 19.635  1.00 33.04  ? 172 ARG C N   1 
ATOM   7515  C CA  . ARG C 1 172 ? 45.975  -56.023 21.015  1.00 37.44  ? 172 ARG C CA  1 
ATOM   7516  C C   . ARG C 1 172 ? 47.223  -56.142 21.878  1.00 35.38  ? 172 ARG C C   1 
ATOM   7517  O O   . ARG C 1 172 ? 47.319  -55.527 22.947  1.00 41.53  ? 172 ARG C O   1 
ATOM   7518  C CB  . ARG C 1 172 ? 45.148  -57.313 21.068  1.00 38.49  ? 172 ARG C CB  1 
ATOM   7519  C CG  . ARG C 1 172 ? 44.510  -57.581 22.423  1.00 43.53  ? 172 ARG C CG  1 
ATOM   7520  C CD  . ARG C 1 172 ? 45.000  -58.893 23.003  1.00 49.86  ? 172 ARG C CD  1 
ATOM   7521  N NE  . ARG C 1 172 ? 46.389  -58.795 23.442  1.00 51.28  ? 172 ARG C NE  1 
ATOM   7522  C CZ  . ARG C 1 172 ? 47.253  -59.804 23.439  1.00 49.04  ? 172 ARG C CZ  1 
ATOM   7523  N NH1 . ARG C 1 172 ? 46.904  -61.013 23.033  1.00 53.21  ? 172 ARG C NH1 1 
ATOM   7524  N NH2 . ARG C 1 172 ? 48.498  -59.596 23.864  1.00 48.40  ? 172 ARG C NH2 1 
ATOM   7525  N N   . SER C 1 173 ? 48.204  -56.903 21.406  1.00 35.03  ? 173 SER C N   1 
ATOM   7526  C CA  . SER C 1 173 ? 49.452  -57.078 22.143  1.00 38.43  ? 173 SER C CA  1 
ATOM   7527  C C   . SER C 1 173 ? 50.184  -55.754 22.324  1.00 35.41  ? 173 SER C C   1 
ATOM   7528  O O   . SER C 1 173 ? 50.620  -55.422 23.432  1.00 42.12  ? 173 SER C O   1 
ATOM   7529  C CB  . SER C 1 173 ? 50.335  -58.085 21.408  1.00 36.90  ? 173 SER C CB  1 
ATOM   7530  O OG  . SER C 1 173 ? 51.495  -58.365 22.159  1.00 45.27  ? 173 SER C OG  1 
ATOM   7531  N N   . ALA C 1 174 ? 50.326  -54.982 21.243  1.00 34.28  ? 174 ALA C N   1 
ATOM   7532  C CA  . ALA C 1 174 ? 51.016  -53.693 21.314  1.00 36.95  ? 174 ALA C CA  1 
ATOM   7533  C C   . ALA C 1 174 ? 50.459  -52.821 22.431  1.00 35.78  ? 174 ALA C C   1 
ATOM   7534  O O   . ALA C 1 174 ? 51.217  -52.261 23.231  1.00 34.07  ? 174 ALA C O   1 
ATOM   7535  C CB  . ALA C 1 174 ? 50.905  -52.964 19.973  1.00 34.22  ? 174 ALA C CB  1 
ATOM   7536  N N   . ILE C 1 175 ? 49.125  -52.710 22.511  1.00 35.46  ? 175 ILE C N   1 
ATOM   7537  C CA  . ILE C 1 175 ? 48.505  -51.861 23.534  1.00 40.47  ? 175 ILE C CA  1 
ATOM   7538  C C   . ILE C 1 175 ? 48.847  -52.342 24.941  1.00 38.93  ? 175 ILE C C   1 
ATOM   7539  O O   . ILE C 1 175 ? 49.161  -51.532 25.821  1.00 43.94  ? 175 ILE C O   1 
ATOM   7540  C CB  . ILE C 1 175 ? 46.978  -51.775 23.341  1.00 38.39  ? 175 ILE C CB  1 
ATOM   7541  C CG1 . ILE C 1 175 ? 46.640  -51.122 22.002  1.00 35.27  ? 175 ILE C CG1 1 
ATOM   7542  C CG2 . ILE C 1 175 ? 46.353  -50.993 24.486  1.00 36.37  ? 175 ILE C CG2 1 
ATOM   7543  C CD1 . ILE C 1 175 ? 45.252  -51.431 21.518  1.00 37.13  ? 175 ILE C CD1 1 
ATOM   7544  N N   . GLN C 1 176 ? 48.769  -53.649 25.196  1.00 36.93  ? 176 GLN C N   1 
ATOM   7545  C CA  . GLN C 1 176 ? 49.027  -54.100 26.561  1.00 43.31  ? 176 GLN C CA  1 
ATOM   7546  C C   . GLN C 1 176 ? 50.453  -53.789 26.992  1.00 39.83  ? 176 GLN C C   1 
ATOM   7547  O O   . GLN C 1 176 ? 50.699  -53.437 28.151  1.00 50.59  ? 176 GLN C O   1 
ATOM   7548  C CB  . GLN C 1 176 ? 48.745  -55.589 26.708  1.00 50.21  ? 176 GLN C CB  1 
ATOM   7549  C CG  . GLN C 1 176 ? 47.945  -55.895 27.975  1.00 49.63  ? 176 GLN C CG  1 
ATOM   7550  C CD  . GLN C 1 176 ? 47.331  -57.274 27.925  1.00 55.48  ? 176 GLN C CD  1 
ATOM   7551  O OE1 . GLN C 1 176 ? 46.208  -57.456 27.458  1.00 63.22  ? 176 GLN C OE1 1 
ATOM   7552  N NE2 . GLN C 1 176 ? 48.078  -58.267 28.393  1.00 56.94  ? 176 GLN C NE2 1 
ATOM   7553  N N   . GLU C 1 177 ? 51.407  -53.903 26.081  1.00 44.70  ? 177 GLU C N   1 
ATOM   7554  C CA  . GLU C 1 177 ? 52.783  -53.606 26.459  1.00 43.39  ? 177 GLU C CA  1 
ATOM   7555  C C   . GLU C 1 177 ? 53.030  -52.106 26.566  1.00 44.32  ? 177 GLU C C   1 
ATOM   7556  O O   . GLU C 1 177 ? 53.727  -51.652 27.479  1.00 47.39  ? 177 GLU C O   1 
ATOM   7557  C CB  . GLU C 1 177 ? 53.748  -54.222 25.452  1.00 44.96  ? 177 GLU C CB  1 
ATOM   7558  C CG  . GLU C 1 177 ? 55.204  -53.892 25.719  1.00 50.75  ? 177 GLU C CG  1 
ATOM   7559  C CD  . GLU C 1 177 ? 56.102  -54.449 24.640  1.00 63.67  ? 177 GLU C CD  1 
ATOM   7560  O OE1 . GLU C 1 177 ? 55.778  -54.240 23.446  1.00 57.20  ? 177 GLU C OE1 1 
ATOM   7561  O OE2 . GLU C 1 177 ? 57.120  -55.094 24.981  1.00 67.91  ? 177 GLU C OE2 1 
ATOM   7562  N N   . LEU C 1 178 ? 52.480  -51.321 25.647  1.00 41.33  ? 178 LEU C N   1 
ATOM   7563  C CA  . LEU C 1 178 ? 52.840  -49.914 25.571  1.00 39.87  ? 178 LEU C CA  1 
ATOM   7564  C C   . LEU C 1 178 ? 52.135  -49.065 26.615  1.00 43.67  ? 178 LEU C C   1 
ATOM   7565  O O   . LEU C 1 178 ? 52.626  -47.976 26.932  1.00 44.75  ? 178 LEU C O   1 
ATOM   7566  C CB  . LEU C 1 178 ? 52.536  -49.373 24.176  1.00 33.09  ? 178 LEU C CB  1 
ATOM   7567  C CG  . LEU C 1 178 ? 53.440  -49.944 23.097  1.00 33.84  ? 178 LEU C CG  1 
ATOM   7568  C CD1 . LEU C 1 178 ? 52.808  -49.714 21.749  1.00 31.91  ? 178 LEU C CD1 1 
ATOM   7569  C CD2 . LEU C 1 178 ? 54.802  -49.299 23.179  1.00 31.89  ? 178 LEU C CD2 1 
ATOM   7570  N N   . ILE C 1 179 ? 51.018  -49.547 27.170  1.00 43.26  ? 179 ILE C N   1 
ATOM   7571  C CA  . ILE C 1 179 ? 50.202  -48.752 28.083  1.00 41.41  ? 179 ILE C CA  1 
ATOM   7572  C C   . ILE C 1 179 ? 50.885  -48.484 29.422  1.00 44.85  ? 179 ILE C C   1 
ATOM   7573  O O   . ILE C 1 179 ? 50.524  -47.522 30.107  1.00 44.17  ? 179 ILE C O   1 
ATOM   7574  C CB  . ILE C 1 179 ? 48.845  -49.446 28.312  1.00 47.72  ? 179 ILE C CB  1 
ATOM   7575  C CG1 . ILE C 1 179 ? 47.831  -48.480 28.921  1.00 45.67  ? 179 ILE C CG1 1 
ATOM   7576  C CG2 . ILE C 1 179 ? 49.007  -50.667 29.216  1.00 46.96  ? 179 ILE C CG2 1 
ATOM   7577  C CD1 . ILE C 1 179 ? 47.761  -47.180 28.221  1.00 42.18  ? 179 ILE C CD1 1 
ATOM   7578  N N   . ALA C 1 180 ? 51.868  -49.294 29.826  1.00 42.33  ? 180 ALA C N   1 
ATOM   7579  C CA  . ALA C 1 180 ? 52.357  -49.205 31.201  1.00 45.74  ? 180 ALA C CA  1 
ATOM   7580  C C   . ALA C 1 180 ? 53.253  -47.992 31.458  1.00 46.92  ? 180 ALA C C   1 
ATOM   7581  O O   . ALA C 1 180 ? 53.411  -47.600 32.620  1.00 48.43  ? 180 ALA C O   1 
ATOM   7582  C CB  . ALA C 1 180 ? 53.098  -50.495 31.594  1.00 31.44  ? 180 ALA C CB  1 
ATOM   7583  N N   . GLU C 1 181 ? 53.835  -47.381 30.420  1.00 43.39  ? 181 GLU C N   1 
ATOM   7584  C CA  . GLU C 1 181 ? 54.869  -46.371 30.647  1.00 40.79  ? 181 GLU C CA  1 
ATOM   7585  C C   . GLU C 1 181 ? 54.270  -45.018 31.029  1.00 41.63  ? 181 GLU C C   1 
ATOM   7586  O O   . GLU C 1 181 ? 54.834  -44.303 31.864  1.00 46.76  ? 181 GLU C O   1 
ATOM   7587  C CB  . GLU C 1 181 ? 55.766  -46.243 29.402  1.00 41.92  ? 181 GLU C CB  1 
ATOM   7588  C CG  . GLU C 1 181 ? 56.937  -45.240 29.520  1.00 38.45  ? 181 GLU C CG  1 
ATOM   7589  C CD  . GLU C 1 181 ? 57.813  -45.112 28.238  1.00 44.27  ? 181 GLU C CD  1 
ATOM   7590  O OE1 . GLU C 1 181 ? 57.623  -45.878 27.255  1.00 38.13  ? 181 GLU C OE1 1 
ATOM   7591  O OE2 . GLU C 1 181 ? 58.713  -44.234 28.228  1.00 44.64  ? 181 GLU C OE2 1 
ATOM   7592  N N   . THR C 1 182 ? 53.138  -44.639 30.434  1.00 37.23  ? 182 THR C N   1 
ATOM   7593  C CA  . THR C 1 182 ? 52.526  -43.344 30.712  1.00 39.38  ? 182 THR C CA  1 
ATOM   7594  C C   . THR C 1 182 ? 51.040  -43.415 31.003  1.00 41.94  ? 182 THR C C   1 
ATOM   7595  O O   . THR C 1 182 ? 50.465  -42.403 31.422  1.00 43.88  ? 182 THR C O   1 
ATOM   7596  C CB  . THR C 1 182 ? 52.720  -42.379 29.536  1.00 36.18  ? 182 THR C CB  1 
ATOM   7597  O OG1 . THR C 1 182 ? 51.907  -42.821 28.440  1.00 39.53  ? 182 THR C OG1 1 
ATOM   7598  C CG2 . THR C 1 182 ? 54.191  -42.308 29.104  1.00 39.23  ? 182 THR C CG2 1 
ATOM   7599  N N   . GLY C 1 183 ? 50.406  -44.564 30.810  1.00 38.94  ? 183 GLY C N   1 
ATOM   7600  C CA  . GLY C 1 183 ? 48.967  -44.643 30.837  1.00 41.72  ? 183 GLY C CA  1 
ATOM   7601  C C   . GLY C 1 183 ? 48.315  -44.251 29.540  1.00 41.71  ? 183 GLY C C   1 
ATOM   7602  O O   . GLY C 1 183 ? 47.082  -44.235 29.463  1.00 40.18  ? 183 GLY C O   1 
ATOM   7603  N N   . MET C 1 184 ? 49.103  -43.981 28.500  1.00 44.12  ? 184 MET C N   1 
ATOM   7604  C CA  . MET C 1 184 ? 48.574  -43.431 27.263  1.00 44.72  ? 184 MET C CA  1 
ATOM   7605  C C   . MET C 1 184 ? 49.233  -44.097 26.063  1.00 39.52  ? 184 MET C C   1 
ATOM   7606  O O   . MET C 1 184 ? 50.444  -44.335 26.061  1.00 38.21  ? 184 MET C O   1 
ATOM   7607  C CB  . MET C 1 184 ? 48.791  -41.916 27.222  1.00 42.15  ? 184 MET C CB  1 
ATOM   7608  C CG  . MET C 1 184 ? 47.640  -41.135 27.823  1.00 50.06  ? 184 MET C CG  1 
ATOM   7609  S SD  . MET C 1 184 ? 47.978  -39.368 27.983  1.00 69.98  ? 184 MET C SD  1 
ATOM   7610  C CE  . MET C 1 184 ? 49.608  -39.373 28.731  1.00 62.39  ? 184 MET C CE  1 
ATOM   7611  N N   . VAL C 1 185 ? 48.422  -44.389 25.045  1.00 34.85  ? 185 VAL C N   1 
ATOM   7612  C CA  . VAL C 1 185 ? 48.864  -45.016 23.807  1.00 37.67  ? 185 VAL C CA  1 
ATOM   7613  C C   . VAL C 1 185 ? 48.085  -44.392 22.655  1.00 36.74  ? 185 VAL C C   1 
ATOM   7614  O O   . VAL C 1 185 ? 46.932  -43.989 22.818  1.00 37.69  ? 185 VAL C O   1 
ATOM   7615  C CB  . VAL C 1 185 ? 48.659  -46.549 23.845  1.00 34.98  ? 185 VAL C CB  1 
ATOM   7616  C CG1 . VAL C 1 185 ? 48.897  -47.150 22.495  1.00 35.45  ? 185 VAL C CG1 1 
ATOM   7617  C CG2 . VAL C 1 185 ? 49.577  -47.184 24.868  1.00 34.73  ? 185 VAL C CG2 1 
ATOM   7618  N N   . ILE C 1 186 ? 48.719  -44.281 21.485  1.00 31.97  ? 186 ILE C N   1 
ATOM   7619  C CA  . ILE C 1 186 ? 48.043  -43.747 20.310  1.00 30.34  ? 186 ILE C CA  1 
ATOM   7620  C C   . ILE C 1 186 ? 48.173  -44.736 19.159  1.00 29.19  ? 186 ILE C C   1 
ATOM   7621  O O   . ILE C 1 186 ? 49.243  -45.309 18.936  1.00 33.77  ? 186 ILE C O   1 
ATOM   7622  C CB  . ILE C 1 186 ? 48.596  -42.362 19.928  1.00 33.37  ? 186 ILE C CB  1 
ATOM   7623  C CG1 . ILE C 1 186 ? 47.887  -41.829 18.679  1.00 36.49  ? 186 ILE C CG1 1 
ATOM   7624  C CG2 . ILE C 1 186 ? 50.139  -42.398 19.777  1.00 36.74  ? 186 ILE C CG2 1 
ATOM   7625  C CD1 . ILE C 1 186 ? 47.988  -40.322 18.507  1.00 33.65  ? 186 ILE C CD1 1 
ATOM   7626  N N   . ALA C 1 187 ? 47.077  -44.967 18.453  1.00 32.74  ? 187 ALA C N   1 
ATOM   7627  C CA  . ALA C 1 187 ? 47.067  -45.803 17.264  1.00 30.17  ? 187 ALA C CA  1 
ATOM   7628  C C   . ALA C 1 187 ? 46.808  -44.917 16.059  1.00 33.97  ? 187 ALA C C   1 
ATOM   7629  O O   . ALA C 1 187 ? 45.930  -44.043 16.108  1.00 32.61  ? 187 ALA C O   1 
ATOM   7630  C CB  . ALA C 1 187 ? 45.998  -46.889 17.360  1.00 32.90  ? 187 ALA C CB  1 
ATOM   7631  N N   . LYS C 1 188 ? 47.579  -45.128 14.988  1.00 26.29  ? 188 LYS C N   1 
ATOM   7632  C CA  . LYS C 1 188 ? 47.511  -44.251 13.825  1.00 33.97  ? 188 LYS C CA  1 
ATOM   7633  C C   . LYS C 1 188 ? 47.489  -45.055 12.533  1.00 34.32  ? 188 LYS C C   1 
ATOM   7634  O O   . LYS C 1 188 ? 48.261  -46.004 12.361  1.00 33.22  ? 188 LYS C O   1 
ATOM   7635  C CB  . LYS C 1 188 ? 48.695  -43.278 13.740  1.00 36.80  ? 188 LYS C CB  1 
ATOM   7636  C CG  . LYS C 1 188 ? 48.914  -42.357 14.919  1.00 38.41  ? 188 LYS C CG  1 
ATOM   7637  C CD  . LYS C 1 188 ? 50.324  -41.771 14.850  1.00 44.26  ? 188 LYS C CD  1 
ATOM   7638  C CE  . LYS C 1 188 ? 50.788  -41.211 16.194  1.00 47.61  ? 188 LYS C CE  1 
ATOM   7639  N NZ  . LYS C 1 188 ? 51.451  -39.865 16.039  1.00 49.99  ? 188 LYS C NZ  1 
ATOM   7640  N N   . GLN C 1 189 ? 46.616  -44.642 11.626  1.00 30.69  ? 189 GLN C N   1 
ATOM   7641  C CA  . GLN C 1 189 ? 46.613  -45.169 10.271  1.00 41.41  ? 189 GLN C CA  1 
ATOM   7642  C C   . GLN C 1 189 ? 47.960  -44.938 9.596   1.00 39.51  ? 189 GLN C C   1 
ATOM   7643  O O   . GLN C 1 189 ? 48.599  -43.895 9.790   1.00 36.29  ? 189 GLN C O   1 
ATOM   7644  C CB  . GLN C 1 189 ? 45.503  -44.503 9.470   1.00 33.01  ? 189 GLN C CB  1 
ATOM   7645  C CG  . GLN C 1 189 ? 45.662  -43.004 9.335   1.00 42.57  ? 189 GLN C CG  1 
ATOM   7646  C CD  . GLN C 1 189 ? 44.704  -42.434 8.315   1.00 52.82  ? 189 GLN C CD  1 
ATOM   7647  O OE1 . GLN C 1 189 ? 43.664  -43.037 8.024   1.00 53.44  ? 189 GLN C OE1 1 
ATOM   7648  N NE2 . GLN C 1 189 ? 45.049  -41.270 7.753   1.00 53.33  ? 189 GLN C NE2 1 
ATOM   7649  N N   . ASP C 1 190 ? 48.386  -45.910 8.780   1.00 35.71  ? 190 ASP C N   1 
ATOM   7650  C CA  . ASP C 1 190 ? 49.737  -45.833 8.225   1.00 37.94  ? 190 ASP C CA  1 
ATOM   7651  C C   . ASP C 1 190 ? 49.887  -44.674 7.248   1.00 44.47  ? 190 ASP C C   1 
ATOM   7652  O O   . ASP C 1 190 ? 50.915  -43.985 7.256   1.00 42.02  ? 190 ASP C O   1 
ATOM   7653  C CB  . ASP C 1 190 ? 50.135  -47.133 7.545   1.00 36.29  ? 190 ASP C CB  1 
ATOM   7654  C CG  . ASP C 1 190 ? 51.628  -47.372 7.621   1.00 34.04  ? 190 ASP C CG  1 
ATOM   7655  O OD1 . ASP C 1 190 ? 52.293  -46.598 8.339   1.00 32.77  ? 190 ASP C OD1 1 
ATOM   7656  O OD2 . ASP C 1 190 ? 52.136  -48.329 7.000   1.00 36.70  ? 190 ASP C OD2 1 
ATOM   7657  N N   . ARG C 1 191 ? 48.892  -44.442 6.394   1.00 40.79  ? 191 ARG C N   1 
ATOM   7658  C CA  . ARG C 1 191 ? 49.008  -43.346 5.442   1.00 43.03  ? 191 ARG C CA  1 
ATOM   7659  C C   . ARG C 1 191 ? 48.067  -42.206 5.840   1.00 48.18  ? 191 ARG C C   1 
ATOM   7660  O O   . ARG C 1 191 ? 48.482  -41.248 6.509   1.00 42.53  ? 191 ARG C O   1 
ATOM   7661  C CB  . ARG C 1 191 ? 48.734  -43.830 4.002   1.00 46.43  ? 191 ARG C CB  1 
ATOM   7662  C CG  . ARG C 1 191 ? 49.970  -44.412 3.257   1.00 44.16  ? 191 ARG C CG  1 
ATOM   7663  C CD  . ARG C 1 191 ? 49.707  -44.598 1.756   1.00 46.83  ? 191 ARG C CD  1 
ATOM   7664  N NE  . ARG C 1 191 ? 50.693  -45.426 1.056   1.00 50.72  ? 191 ARG C NE  1 
ATOM   7665  C CZ  . ARG C 1 191 ? 50.668  -46.754 0.981   1.00 47.56  ? 191 ARG C CZ  1 
ATOM   7666  N NH1 . ARG C 1 191 ? 49.743  -47.471 1.603   1.00 49.21  ? 191 ARG C NH1 1 
ATOM   7667  N NH2 . ARG C 1 191 ? 51.588  -47.380 0.253   1.00 47.43  ? 191 ARG C NH2 1 
ATOM   7668  N N   . GLY C 1 197 ? 41.901  -39.705 12.142  1.00 48.84  ? 197 GLY C N   1 
ATOM   7669  C CA  . GLY C 1 197 ? 43.176  -40.166 11.606  1.00 48.39  ? 197 GLY C CA  1 
ATOM   7670  C C   . GLY C 1 197 ? 43.871  -40.978 12.668  1.00 46.32  ? 197 GLY C C   1 
ATOM   7671  O O   . GLY C 1 197 ? 44.386  -42.087 12.438  1.00 41.30  ? 197 GLY C O   1 
ATOM   7672  N N   . ASN C 1 198 ? 43.825  -40.457 13.886  1.00 38.69  ? 198 ASN C N   1 
ATOM   7673  C CA  . ASN C 1 198 ? 44.528  -41.026 15.023  1.00 42.77  ? 198 ASN C CA  1 
ATOM   7674  C C   . ASN C 1 198 ? 43.536  -41.243 16.155  1.00 42.43  ? 198 ASN C C   1 
ATOM   7675  O O   . ASN C 1 198 ? 42.566  -40.496 16.302  1.00 35.77  ? 198 ASN C O   1 
ATOM   7676  C CB  . ASN C 1 198 ? 45.662  -40.109 15.477  1.00 36.29  ? 198 ASN C CB  1 
ATOM   7677  C CG  . ASN C 1 198 ? 46.720  -39.954 14.433  1.00 40.95  ? 198 ASN C CG  1 
ATOM   7678  O OD1 . ASN C 1 198 ? 46.720  -40.643 13.411  1.00 42.72  ? 198 ASN C OD1 1 
ATOM   7679  N ND2 . ASN C 1 198 ? 47.645  -39.033 14.677  1.00 47.13  ? 198 ASN C ND2 1 
ATOM   7680  N N   . ILE C 1 199 ? 43.782  -42.287 16.931  1.00 38.84  ? 199 ILE C N   1 
ATOM   7681  C CA  . ILE C 1 199 ? 42.897  -42.711 18.001  1.00 40.59  ? 199 ILE C CA  1 
ATOM   7682  C C   . ILE C 1 199 ? 43.739  -42.924 19.244  1.00 39.34  ? 199 ILE C C   1 
ATOM   7683  O O   . ILE C 1 199 ? 44.675  -43.735 19.232  1.00 34.15  ? 199 ILE C O   1 
ATOM   7684  C CB  . ILE C 1 199 ? 42.141  -43.996 17.639  1.00 38.23  ? 199 ILE C CB  1 
ATOM   7685  C CG1 . ILE C 1 199 ? 41.297  -43.770 16.397  1.00 41.32  ? 199 ILE C CG1 1 
ATOM   7686  C CG2 . ILE C 1 199 ? 41.297  -44.439 18.788  1.00 39.24  ? 199 ILE C CG2 1 
ATOM   7687  C CD1 . ILE C 1 199 ? 40.759  -45.037 15.804  1.00 44.17  ? 199 ILE C CD1 1 
ATOM   7688  N N   . GLY C 1 200 ? 43.399  -42.215 20.314  1.00 38.42  ? 200 GLY C N   1 
ATOM   7689  C CA  . GLY C 1 200 ? 44.085  -42.364 21.576  1.00 41.34  ? 200 GLY C CA  1 
ATOM   7690  C C   . GLY C 1 200 ? 43.408  -43.380 22.480  1.00 46.75  ? 200 GLY C C   1 
ATOM   7691  O O   . GLY C 1 200 ? 42.214  -43.638 22.375  1.00 48.43  ? 200 GLY C O   1 
ATOM   7692  N N   . ILE C 1 201 ? 44.206  -43.972 23.366  1.00 47.28  ? 201 ILE C N   1 
ATOM   7693  C CA  . ILE C 1 201 ? 43.745  -44.944 24.347  1.00 45.45  ? 201 ILE C CA  1 
ATOM   7694  C C   . ILE C 1 201 ? 44.289  -44.503 25.692  1.00 46.35  ? 201 ILE C C   1 
ATOM   7695  O O   . ILE C 1 201 ? 45.459  -44.118 25.794  1.00 44.52  ? 201 ILE C O   1 
ATOM   7696  C CB  . ILE C 1 201 ? 44.210  -46.382 24.022  1.00 44.03  ? 201 ILE C CB  1 
ATOM   7697  C CG1 . ILE C 1 201 ? 43.713  -46.820 22.647  1.00 38.67  ? 201 ILE C CG1 1 
ATOM   7698  C CG2 . ILE C 1 201 ? 43.700  -47.359 25.079  1.00 49.49  ? 201 ILE C CG2 1 
ATOM   7699  C CD1 . ILE C 1 201 ? 44.799  -46.817 21.593  1.00 40.94  ? 201 ILE C CD1 1 
ATOM   7700  N N   . SER C 1 202 ? 43.446  -44.560 26.723  1.00 49.91  ? 202 SER C N   1 
ATOM   7701  C CA  . SER C 1 202 ? 43.757  -43.907 27.987  1.00 49.07  ? 202 SER C CA  1 
ATOM   7702  C C   . SER C 1 202 ? 43.227  -44.717 29.163  1.00 50.86  ? 202 SER C C   1 
ATOM   7703  O O   . SER C 1 202 ? 42.059  -45.117 29.178  1.00 48.41  ? 202 SER C O   1 
ATOM   7704  C CB  . SER C 1 202 ? 43.169  -42.489 28.007  1.00 51.28  ? 202 SER C CB  1 
ATOM   7705  O OG  . SER C 1 202 ? 43.658  -41.753 29.111  1.00 58.97  ? 202 SER C OG  1 
ATOM   7706  N N   . THR C 1 203 ? 44.094  -44.959 30.141  1.00 47.91  ? 203 THR C N   1 
ATOM   7707  C CA  . THR C 1 203 ? 43.660  -45.543 31.396  1.00 52.39  ? 203 THR C CA  1 
ATOM   7708  C C   . THR C 1 203 ? 42.998  -44.524 32.307  1.00 59.00  ? 203 THR C C   1 
ATOM   7709  O O   . THR C 1 203 ? 42.299  -44.916 33.243  1.00 64.37  ? 203 THR C O   1 
ATOM   7710  C CB  . THR C 1 203 ? 44.843  -46.149 32.129  1.00 48.94  ? 203 THR C CB  1 
ATOM   7711  O OG1 . THR C 1 203 ? 45.808  -45.122 32.363  1.00 47.04  ? 203 THR C OG1 1 
ATOM   7712  C CG2 . THR C 1 203 ? 45.460  -47.237 31.306  1.00 48.44  ? 203 THR C CG2 1 
ATOM   7713  N N   . SER C 1 204 ? 43.219  -43.239 32.071  1.00 57.96  ? 204 SER C N   1 
ATOM   7714  C CA  . SER C 1 204 ? 42.646  -42.169 32.864  1.00 60.05  ? 204 SER C CA  1 
ATOM   7715  C C   . SER C 1 204 ? 41.572  -41.432 32.072  1.00 67.33  ? 204 SER C C   1 
ATOM   7716  O O   . SER C 1 204 ? 41.532  -41.503 30.838  1.00 66.46  ? 204 SER C O   1 
ATOM   7717  C CB  . SER C 1 204 ? 43.735  -41.180 33.305  1.00 64.78  ? 204 SER C CB  1 
ATOM   7718  O OG  . SER C 1 204 ? 44.279  -41.540 34.565  1.00 60.46  ? 204 SER C OG  1 
ATOM   7719  N N   . PRO C 1 205 ? 40.660  -40.729 32.752  1.00 68.98  ? 205 PRO C N   1 
ATOM   7720  C CA  . PRO C 1 205 ? 39.689  -39.912 32.020  1.00 69.49  ? 205 PRO C CA  1 
ATOM   7721  C C   . PRO C 1 205 ? 40.240  -38.528 31.732  1.00 69.83  ? 205 PRO C C   1 
ATOM   7722  O O   . PRO C 1 205 ? 39.966  -37.963 30.668  1.00 70.46  ? 205 PRO C O   1 
ATOM   7723  C CB  . PRO C 1 205 ? 38.477  -39.872 32.962  1.00 66.40  ? 205 PRO C CB  1 
ATOM   7724  C CG  . PRO C 1 205 ? 39.026  -40.171 34.334  1.00 71.41  ? 205 PRO C CG  1 
ATOM   7725  C CD  . PRO C 1 205 ? 40.450  -40.653 34.210  1.00 71.88  ? 205 PRO C CD  1 
ATOM   7726  N N   . GLU C 1 206 ? 41.051  -37.988 32.650  1.00 70.46  ? 206 GLU C N   1 
ATOM   7727  C CA  . GLU C 1 206 ? 41.685  -36.682 32.471  1.00 72.82  ? 206 GLU C CA  1 
ATOM   7728  C C   . GLU C 1 206 ? 42.684  -36.721 31.319  1.00 75.54  ? 206 GLU C C   1 
ATOM   7729  O O   . GLU C 1 206 ? 43.803  -36.203 31.428  1.00 72.05  ? 206 GLU C O   1 
ATOM   7730  C CB  . GLU C 1 206 ? 42.385  -36.230 33.759  1.00 72.68  ? 206 GLU C CB  1 
ATOM   7731  C CG  . GLU C 1 206 ? 41.547  -36.330 35.028  1.00 76.81  ? 206 GLU C CG  1 
ATOM   7732  C CD  . GLU C 1 206 ? 41.900  -37.547 35.873  1.00 81.08  ? 206 GLU C CD  1 
ATOM   7733  O OE1 . GLU C 1 206 ? 42.824  -38.304 35.489  1.00 78.82  ? 206 GLU C OE1 1 
ATOM   7734  O OE2 . GLU C 1 206 ? 41.261  -37.737 36.929  1.00 79.73  ? 206 GLU C OE2 1 
ATOM   7735  N N   . SER C 1 207 ? 42.272  -37.326 30.209  1.00 75.52  ? 207 SER C N   1 
ATOM   7736  C CA  . SER C 1 207 ? 43.120  -37.567 29.054  1.00 71.54  ? 207 SER C CA  1 
ATOM   7737  C C   . SER C 1 207 ? 42.925  -36.468 28.018  1.00 69.86  ? 207 SER C C   1 
ATOM   7738  O O   . SER C 1 207 ? 41.817  -35.948 27.844  1.00 73.02  ? 207 SER C O   1 
ATOM   7739  C CB  . SER C 1 207 ? 42.794  -38.931 28.443  1.00 71.64  ? 207 SER C CB  1 
ATOM   7740  O OG  . SER C 1 207 ? 41.853  -39.650 29.238  1.00 64.08  ? 207 SER C OG  1 
ATOM   7741  N N   . SER C 1 208 ? 44.008  -36.112 27.333  1.00 65.03  ? 208 SER C N   1 
ATOM   7742  C CA  . SER C 1 208 ? 43.943  -35.055 26.330  1.00 63.55  ? 208 SER C CA  1 
ATOM   7743  C C   . SER C 1 208 ? 44.968  -35.377 25.250  1.00 59.01  ? 208 SER C C   1 
ATOM   7744  O O   . SER C 1 208 ? 46.174  -35.286 25.496  1.00 60.38  ? 208 SER C O   1 
ATOM   7745  C CB  . SER C 1 208 ? 44.197  -33.685 26.963  1.00 67.88  ? 208 SER C CB  1 
ATOM   7746  O OG  . SER C 1 208 ? 43.968  -32.623 26.046  1.00 66.74  ? 208 SER C OG  1 
ATOM   7747  N N   . PHE C 1 209 ? 44.486  -35.766 24.066  1.00 54.03  ? 209 PHE C N   1 
ATOM   7748  C CA  . PHE C 1 209 ? 45.323  -36.087 22.911  1.00 51.28  ? 209 PHE C CA  1 
ATOM   7749  C C   . PHE C 1 209 ? 45.045  -35.070 21.812  1.00 47.15  ? 209 PHE C C   1 
ATOM   7750  O O   . PHE C 1 209 ? 44.158  -35.290 20.975  1.00 50.81  ? 209 PHE C O   1 
ATOM   7751  C CB  . PHE C 1 209 ? 45.048  -37.496 22.377  1.00 48.67  ? 209 PHE C CB  1 
ATOM   7752  C CG  . PHE C 1 209 ? 45.307  -38.612 23.350  1.00 53.75  ? 209 PHE C CG  1 
ATOM   7753  C CD1 . PHE C 1 209 ? 44.409  -38.885 24.373  1.00 57.08  ? 209 PHE C CD1 1 
ATOM   7754  C CD2 . PHE C 1 209 ? 46.414  -39.434 23.201  1.00 48.85  ? 209 PHE C CD2 1 
ATOM   7755  C CE1 . PHE C 1 209 ? 44.628  -39.926 25.253  1.00 54.24  ? 209 PHE C CE1 1 
ATOM   7756  C CE2 . PHE C 1 209 ? 46.634  -40.478 24.083  1.00 50.58  ? 209 PHE C CE2 1 
ATOM   7757  C CZ  . PHE C 1 209 ? 45.731  -40.724 25.106  1.00 51.46  ? 209 PHE C CZ  1 
ATOM   7758  N N   . PRO C 1 210 ? 45.776  -33.957 21.761  1.00 51.81  ? 210 PRO C N   1 
ATOM   7759  C CA  . PRO C 1 210 ? 45.530  -32.956 20.708  1.00 52.72  ? 210 PRO C CA  1 
ATOM   7760  C C   . PRO C 1 210 ? 45.615  -33.547 19.306  1.00 51.99  ? 210 PRO C C   1 
ATOM   7761  O O   . PRO C 1 210 ? 46.584  -34.222 18.955  1.00 51.77  ? 210 PRO C O   1 
ATOM   7762  C CB  . PRO C 1 210 ? 46.634  -31.924 20.948  1.00 49.82  ? 210 PRO C CB  1 
ATOM   7763  C CG  . PRO C 1 210 ? 46.889  -32.008 22.413  1.00 50.63  ? 210 PRO C CG  1 
ATOM   7764  C CD  . PRO C 1 210 ? 46.723  -33.460 22.776  1.00 50.32  ? 210 PRO C CD  1 
ATOM   7765  N N   . GLY C 1 211 ? 44.581  -33.286 18.498  1.00 53.98  ? 211 GLY C N   1 
ATOM   7766  C CA  . GLY C 1 211 ? 44.557  -33.697 17.104  1.00 51.72  ? 211 GLY C CA  1 
ATOM   7767  C C   . GLY C 1 211 ? 44.094  -35.111 16.842  1.00 55.71  ? 211 GLY C C   1 
ATOM   7768  O O   . GLY C 1 211 ? 44.001  -35.510 15.671  1.00 59.62  ? 211 GLY C O   1 
ATOM   7769  N N   . THR C 1 212 ? 43.810  -35.879 17.887  1.00 54.54  ? 212 THR C N   1 
ATOM   7770  C CA  . THR C 1 212 ? 43.349  -37.245 17.737  1.00 52.15  ? 212 THR C CA  1 
ATOM   7771  C C   . THR C 1 212 ? 41.848  -37.242 17.472  1.00 55.44  ? 212 THR C C   1 
ATOM   7772  O O   . THR C 1 212 ? 41.115  -36.401 17.994  1.00 60.38  ? 212 THR C O   1 
ATOM   7773  C CB  . THR C 1 212 ? 43.687  -38.040 19.001  1.00 50.78  ? 212 THR C CB  1 
ATOM   7774  O OG1 . THR C 1 212 ? 43.768  -39.436 18.700  1.00 50.30  ? 212 THR C OG1 1 
ATOM   7775  C CG2 . THR C 1 212 ? 42.642  -37.832 20.057  1.00 48.96  ? 212 THR C CG2 1 
ATOM   7776  N N   . ARG C 1 213 ? 41.403  -38.139 16.600  1.00 54.59  ? 213 ARG C N   1 
ATOM   7777  C CA  . ARG C 1 213 ? 39.978  -38.418 16.451  1.00 56.12  ? 213 ARG C CA  1 
ATOM   7778  C C   . ARG C 1 213 ? 39.587  -39.408 17.547  1.00 55.36  ? 213 ARG C C   1 
ATOM   7779  O O   . ARG C 1 213 ? 40.061  -40.548 17.548  1.00 59.15  ? 213 ARG C O   1 
ATOM   7780  C CB  . ARG C 1 213 ? 39.691  -38.970 15.054  1.00 56.23  ? 213 ARG C CB  1 
ATOM   7781  C CG  . ARG C 1 213 ? 38.547  -39.991 14.977  1.00 60.56  ? 213 ARG C CG  1 
ATOM   7782  C CD  . ARG C 1 213 ? 38.107  -40.284 13.542  1.00 67.70  ? 213 ARG C CD  1 
ATOM   7783  N NE  . ARG C 1 213 ? 38.737  -41.457 12.940  1.00 64.11  ? 213 ARG C NE  1 
ATOM   7784  C CZ  . ARG C 1 213 ? 38.405  -42.716 13.207  1.00 60.17  ? 213 ARG C CZ  1 
ATOM   7785  N NH1 . ARG C 1 213 ? 37.546  -43.019 14.170  1.00 64.85  ? 213 ARG C NH1 1 
ATOM   7786  N NH2 . ARG C 1 213 ? 38.981  -43.696 12.519  1.00 53.71  ? 213 ARG C NH2 1 
ATOM   7787  N N   . GLU C 1 214 ? 38.774  -38.965 18.511  1.00 56.35  ? 214 GLU C N   1 
ATOM   7788  C CA  . GLU C 1 214 ? 38.277  -39.839 19.580  1.00 57.18  ? 214 GLU C CA  1 
ATOM   7789  C C   . GLU C 1 214 ? 39.371  -40.275 20.557  1.00 54.44  ? 214 GLU C C   1 
ATOM   7790  O O   . GLU C 1 214 ? 40.554  -40.337 20.199  1.00 51.74  ? 214 GLU C O   1 
ATOM   7791  C CB  . GLU C 1 214 ? 37.603  -41.081 18.978  1.00 55.16  ? 214 GLU C CB  1 
ATOM   7792  C CG  . GLU C 1 214 ? 36.086  -41.052 18.991  1.00 68.55  ? 214 GLU C CG  1 
ATOM   7793  C CD  . GLU C 1 214 ? 35.471  -41.889 17.871  1.00 72.26  ? 214 GLU C CD  1 
ATOM   7794  O OE1 . GLU C 1 214 ? 34.236  -42.102 17.899  1.00 76.71  ? 214 GLU C OE1 1 
ATOM   7795  O OE2 . GLU C 1 214 ? 36.218  -42.323 16.960  1.00 65.34  ? 214 GLU C OE2 1 
ATOM   7796  N N   . VAL C 1 215 ? 38.988  -40.594 21.795  1.00 52.35  ? 215 VAL C N   1 
ATOM   7797  C CA  . VAL C 1 215 ? 39.928  -41.114 22.785  1.00 52.71  ? 215 VAL C CA  1 
ATOM   7798  C C   . VAL C 1 215 ? 39.249  -42.252 23.540  1.00 57.05  ? 215 VAL C C   1 
ATOM   7799  O O   . VAL C 1 215 ? 38.622  -42.032 24.583  1.00 56.15  ? 215 VAL C O   1 
ATOM   7800  C CB  . VAL C 1 215 ? 40.399  -40.013 23.756  1.00 52.99  ? 215 VAL C CB  1 
ATOM   7801  C CG1 . VAL C 1 215 ? 41.171  -40.609 24.944  1.00 57.83  ? 215 VAL C CG1 1 
ATOM   7802  C CG2 . VAL C 1 215 ? 41.227  -38.975 23.029  1.00 56.71  ? 215 VAL C CG2 1 
ATOM   7803  N N   . LEU C 1 216 ? 39.345  -43.471 23.006  1.00 52.69  ? 216 LEU C N   1 
ATOM   7804  C CA  . LEU C 1 216 ? 38.734  -44.620 23.653  1.00 46.33  ? 216 LEU C CA  1 
ATOM   7805  C C   . LEU C 1 216 ? 39.384  -44.867 25.010  1.00 52.86  ? 216 LEU C C   1 
ATOM   7806  O O   . LEU C 1 216 ? 40.510  -44.436 25.282  1.00 54.87  ? 216 LEU C O   1 
ATOM   7807  C CB  . LEU C 1 216 ? 38.841  -45.855 22.762  1.00 40.68  ? 216 LEU C CB  1 
ATOM   7808  C CG  . LEU C 1 216 ? 38.560  -45.569 21.287  1.00 46.92  ? 216 LEU C CG  1 
ATOM   7809  C CD1 . LEU C 1 216 ? 38.915  -46.751 20.406  1.00 48.69  ? 216 LEU C CD1 1 
ATOM   7810  C CD2 . LEU C 1 216 ? 37.103  -45.173 21.075  1.00 50.21  ? 216 LEU C CD2 1 
ATOM   7811  N N   . ALA C 1 217 ? 38.638  -45.548 25.877  1.00 55.73  ? 217 ALA C N   1 
ATOM   7812  C CA  . ALA C 1 217 ? 39.058  -45.851 27.238  1.00 53.40  ? 217 ALA C CA  1 
ATOM   7813  C C   . ALA C 1 217 ? 39.656  -47.250 27.321  1.00 47.43  ? 217 ALA C C   1 
ATOM   7814  O O   . ALA C 1 217 ? 39.284  -48.149 26.565  1.00 47.05  ? 217 ALA C O   1 
ATOM   7815  C CB  . ALA C 1 217 ? 37.876  -45.735 28.203  1.00 51.51  ? 217 ALA C CB  1 
ATOM   7816  N N   . TYR C 1 218 ? 40.574  -47.432 28.266  1.00 48.24  ? 218 TYR C N   1 
ATOM   7817  C CA  . TYR C 1 218 ? 41.306  -48.685 28.406  1.00 51.77  ? 218 TYR C CA  1 
ATOM   7818  C C   . TYR C 1 218 ? 40.766  -49.517 29.566  1.00 51.78  ? 218 TYR C C   1 
ATOM   7819  O O   . TYR C 1 218 ? 40.666  -49.032 30.698  1.00 53.60  ? 218 TYR C O   1 
ATOM   7820  C CB  . TYR C 1 218 ? 42.800  -48.422 28.606  1.00 50.25  ? 218 TYR C CB  1 
ATOM   7821  C CG  . TYR C 1 218 ? 43.616  -49.689 28.743  1.00 53.76  ? 218 TYR C CG  1 
ATOM   7822  C CD1 . TYR C 1 218 ? 43.843  -50.258 29.993  1.00 51.31  ? 218 TYR C CD1 1 
ATOM   7823  C CD2 . TYR C 1 218 ? 44.147  -50.323 27.626  1.00 53.84  ? 218 TYR C CD2 1 
ATOM   7824  C CE1 . TYR C 1 218 ? 44.573  -51.414 30.127  1.00 55.38  ? 218 TYR C CE1 1 
ATOM   7825  C CE2 . TYR C 1 218 ? 44.890  -51.491 27.751  1.00 54.92  ? 218 TYR C CE2 1 
ATOM   7826  C CZ  . TYR C 1 218 ? 45.097  -52.030 29.008  1.00 55.92  ? 218 TYR C CZ  1 
ATOM   7827  O OH  . TYR C 1 218 ? 45.831  -53.186 29.160  1.00 55.69  ? 218 TYR C OH  1 
ATOM   7828  N N   . ALA C 1 219 ? 40.435  -50.770 29.272  1.00 50.60  ? 219 ALA C N   1 
ATOM   7829  C CA  . ALA C 1 219 ? 40.122  -51.781 30.267  1.00 56.32  ? 219 ALA C CA  1 
ATOM   7830  C C   . ALA C 1 219 ? 40.610  -53.116 29.732  1.00 53.65  ? 219 ALA C C   1 
ATOM   7831  O O   . ALA C 1 219 ? 40.602  -53.339 28.520  1.00 54.97  ? 219 ALA C O   1 
ATOM   7832  C CB  . ALA C 1 219 ? 38.622  -51.837 30.571  1.00 56.42  ? 219 ALA C CB  1 
ATOM   7833  N N   . ASN C 1 220 ? 41.036  -54.003 30.638  1.00 57.10  ? 220 ASN C N   1 
ATOM   7834  C CA  . ASN C 1 220 ? 41.604  -55.281 30.212  1.00 58.84  ? 220 ASN C CA  1 
ATOM   7835  C C   . ASN C 1 220 ? 40.603  -56.067 29.375  1.00 57.68  ? 220 ASN C C   1 
ATOM   7836  O O   . ASN C 1 220 ? 40.893  -56.450 28.237  1.00 56.21  ? 220 ASN C O   1 
ATOM   7837  C CB  . ASN C 1 220 ? 42.071  -56.091 31.423  1.00 56.12  ? 220 ASN C CB  1 
ATOM   7838  C CG  . ASN C 1 220 ? 43.552  -56.423 31.356  1.00 61.22  ? 220 ASN C CG  1 
ATOM   7839  O OD1 . ASN C 1 220 ? 44.083  -56.733 30.290  1.00 60.35  ? 220 ASN C OD1 1 
ATOM   7840  N ND2 . ASN C 1 220 ? 44.235  -56.320 32.489  1.00 61.66  ? 220 ASN C ND2 1 
ATOM   7841  N N   . ASP C 1 221 ? 39.417  -56.318 29.921  1.00 58.46  ? 221 ASP C N   1 
ATOM   7842  C CA  . ASP C 1 221 ? 38.294  -56.665 29.066  1.00 62.51  ? 221 ASP C CA  1 
ATOM   7843  C C   . ASP C 1 221 ? 37.998  -55.481 28.154  1.00 60.60  ? 221 ASP C C   1 
ATOM   7844  O O   . ASP C 1 221 ? 38.177  -54.323 28.539  1.00 62.34  ? 221 ASP C O   1 
ATOM   7845  C CB  . ASP C 1 221 ? 37.060  -57.013 29.901  1.00 64.51  ? 221 ASP C CB  1 
ATOM   7846  C CG  . ASP C 1 221 ? 36.644  -55.878 30.817  1.00 66.69  ? 221 ASP C CG  1 
ATOM   7847  O OD1 . ASP C 1 221 ? 35.918  -54.971 30.348  1.00 60.72  ? 221 ASP C OD1 1 
ATOM   7848  O OD2 . ASP C 1 221 ? 37.058  -55.883 31.998  1.00 70.23  ? 221 ASP C OD2 1 
ATOM   7849  N N   . GLN C 1 222 ? 37.546  -55.778 26.939  1.00 61.77  ? 222 GLN C N   1 
ATOM   7850  C CA  . GLN C 1 222 ? 37.348  -54.858 25.806  1.00 61.14  ? 222 GLN C CA  1 
ATOM   7851  C C   . GLN C 1 222 ? 38.639  -54.693 25.004  1.00 52.83  ? 222 GLN C C   1 
ATOM   7852  O O   . GLN C 1 222 ? 38.624  -53.978 24.002  1.00 51.13  ? 222 GLN C O   1 
ATOM   7853  C CB  . GLN C 1 222 ? 36.826  -53.463 26.211  1.00 63.52  ? 222 GLN C CB  1 
ATOM   7854  C CG  . GLN C 1 222 ? 35.566  -53.472 27.084  1.00 63.17  ? 222 GLN C CG  1 
ATOM   7855  C CD  . GLN C 1 222 ? 34.349  -52.859 26.400  1.00 74.62  ? 222 GLN C CD  1 
ATOM   7856  O OE1 . GLN C 1 222 ? 33.922  -53.304 25.328  1.00 73.13  ? 222 GLN C OE1 1 
ATOM   7857  N NE2 . GLN C 1 222 ? 33.788  -51.822 27.020  1.00 80.09  ? 222 GLN C NE2 1 
ATOM   7858  N N   . LEU C 1 223 ? 39.747  -55.334 25.397  1.00 55.08  ? 223 LEU C N   1 
ATOM   7859  C CA  . LEU C 1 223 ? 40.953  -55.289 24.570  1.00 52.33  ? 223 LEU C CA  1 
ATOM   7860  C C   . LEU C 1 223 ? 40.781  -56.070 23.269  1.00 52.56  ? 223 LEU C C   1 
ATOM   7861  O O   . LEU C 1 223 ? 41.407  -55.724 22.256  1.00 49.96  ? 223 LEU C O   1 
ATOM   7862  C CB  . LEU C 1 223 ? 42.159  -55.821 25.348  1.00 54.43  ? 223 LEU C CB  1 
ATOM   7863  C CG  . LEU C 1 223 ? 42.916  -54.801 26.213  1.00 55.02  ? 223 LEU C CG  1 
ATOM   7864  C CD1 . LEU C 1 223 ? 43.804  -55.500 27.224  1.00 58.56  ? 223 LEU C CD1 1 
ATOM   7865  C CD2 . LEU C 1 223 ? 43.733  -53.845 25.366  1.00 47.07  ? 223 LEU C CD2 1 
ATOM   7866  N N   . ASP C 1 224 ? 39.947  -57.118 23.272  1.00 46.29  ? 224 ASP C N   1 
ATOM   7867  C CA  . ASP C 1 224 ? 39.601  -57.793 22.021  1.00 47.64  ? 224 ASP C CA  1 
ATOM   7868  C C   . ASP C 1 224 ? 38.843  -56.853 21.094  1.00 44.91  ? 224 ASP C C   1 
ATOM   7869  O O   . ASP C 1 224 ? 39.156  -56.737 19.901  1.00 37.20  ? 224 ASP C O   1 
ATOM   7870  C CB  . ASP C 1 224 ? 38.758  -59.043 22.293  1.00 54.66  ? 224 ASP C CB  1 
ATOM   7871  C CG  . ASP C 1 224 ? 39.528  -60.143 23.010  1.00 59.24  ? 224 ASP C CG  1 
ATOM   7872  O OD1 . ASP C 1 224 ? 40.624  -60.530 22.544  1.00 59.88  ? 224 ASP C OD1 1 
ATOM   7873  O OD2 . ASP C 1 224 ? 39.022  -60.625 24.048  1.00 67.07  ? 224 ASP C OD2 1 
ATOM   7874  N N   . THR C 1 225 ? 37.836  -56.169 21.636  1.00 42.91  ? 225 THR C N   1 
ATOM   7875  C CA  . THR C 1 225 ? 37.038  -55.255 20.830  1.00 40.60  ? 225 THR C CA  1 
ATOM   7876  C C   . THR C 1 225 ? 37.852  -54.045 20.403  1.00 39.02  ? 225 THR C C   1 
ATOM   7877  O O   . THR C 1 225 ? 37.751  -53.599 19.252  1.00 37.42  ? 225 THR C O   1 
ATOM   7878  C CB  . THR C 1 225 ? 35.804  -54.831 21.622  1.00 42.70  ? 225 THR C CB  1 
ATOM   7879  O OG1 . THR C 1 225 ? 35.365  -55.939 22.417  1.00 52.55  ? 225 THR C OG1 1 
ATOM   7880  C CG2 . THR C 1 225 ? 34.696  -54.410 20.699  1.00 45.91  ? 225 THR C CG2 1 
ATOM   7881  N N   . LEU C 1 226 ? 38.660  -53.504 21.321  1.00 41.60  ? 226 LEU C N   1 
ATOM   7882  C CA  . LEU C 1 226 ? 39.536  -52.376 21.022  1.00 43.74  ? 226 LEU C CA  1 
ATOM   7883  C C   . LEU C 1 226 ? 40.393  -52.656 19.794  1.00 42.77  ? 226 LEU C C   1 
ATOM   7884  O O   . LEU C 1 226 ? 40.359  -51.906 18.804  1.00 33.97  ? 226 LEU C O   1 
ATOM   7885  C CB  . LEU C 1 226 ? 40.420  -52.084 22.240  1.00 44.19  ? 226 LEU C CB  1 
ATOM   7886  C CG  . LEU C 1 226 ? 40.847  -50.656 22.565  1.00 48.91  ? 226 LEU C CG  1 
ATOM   7887  C CD1 . LEU C 1 226 ? 39.780  -49.656 22.135  1.00 42.35  ? 226 LEU C CD1 1 
ATOM   7888  C CD2 . LEU C 1 226 ? 41.131  -50.538 24.057  1.00 47.79  ? 226 LEU C CD2 1 
ATOM   7889  N N   . ALA C 1 227 ? 41.159  -53.756 19.848  1.00 37.27  ? 227 ALA C N   1 
ATOM   7890  C CA  . ALA C 1 227 ? 42.060  -54.110 18.755  1.00 34.16  ? 227 ALA C CA  1 
ATOM   7891  C C   . ALA C 1 227 ? 41.299  -54.302 17.454  1.00 39.35  ? 227 ALA C C   1 
ATOM   7892  O O   . ALA C 1 227 ? 41.650  -53.708 16.421  1.00 32.81  ? 227 ALA C O   1 
ATOM   7893  C CB  . ALA C 1 227 ? 42.836  -55.376 19.110  1.00 36.98  ? 227 ALA C CB  1 
ATOM   7894  N N   . ASP C 1 228 ? 40.255  -55.143 17.488  1.00 40.22  ? 228 ASP C N   1 
ATOM   7895  C CA  . ASP C 1 228 ? 39.426  -55.360 16.307  1.00 37.53  ? 228 ASP C CA  1 
ATOM   7896  C C   . ASP C 1 228 ? 38.983  -54.039 15.700  1.00 38.27  ? 228 ASP C C   1 
ATOM   7897  O O   . ASP C 1 228 ? 39.166  -53.804 14.502  1.00 36.32  ? 228 ASP C O   1 
ATOM   7898  C CB  . ASP C 1 228 ? 38.205  -56.211 16.658  1.00 38.01  ? 228 ASP C CB  1 
ATOM   7899  C CG  . ASP C 1 228 ? 38.533  -57.693 16.775  1.00 46.80  ? 228 ASP C CG  1 
ATOM   7900  O OD1 . ASP C 1 228 ? 39.699  -58.072 16.507  1.00 46.29  ? 228 ASP C OD1 1 
ATOM   7901  O OD2 . ASP C 1 228 ? 37.615  -58.481 17.119  1.00 50.29  ? 228 ASP C OD2 1 
ATOM   7902  N N   . THR C 1 229 ? 38.439  -53.144 16.529  1.00 40.28  ? 229 THR C N   1 
ATOM   7903  C CA  . THR C 1 229 ? 37.848  -51.917 16.003  1.00 35.98  ? 229 THR C CA  1 
ATOM   7904  C C   . THR C 1 229 ? 38.921  -50.930 15.554  1.00 38.62  ? 229 THR C C   1 
ATOM   7905  O O   . THR C 1 229 ? 38.767  -50.263 14.520  1.00 39.87  ? 229 THR C O   1 
ATOM   7906  C CB  . THR C 1 229 ? 36.924  -51.297 17.057  1.00 41.55  ? 229 THR C CB  1 
ATOM   7907  O OG1 . THR C 1 229 ? 37.626  -51.162 18.295  1.00 44.38  ? 229 THR C OG1 1 
ATOM   7908  C CG2 . THR C 1 229 ? 35.722  -52.180 17.283  1.00 33.13  ? 229 THR C CG2 1 
ATOM   7909  N N   . LEU C 1 230 ? 40.016  -50.827 16.314  1.00 41.61  ? 230 LEU C N   1 
ATOM   7910  C CA  . LEU C 1 230 ? 41.160  -50.037 15.868  1.00 36.02  ? 230 LEU C CA  1 
ATOM   7911  C C   . LEU C 1 230 ? 41.645  -50.517 14.510  1.00 35.80  ? 230 LEU C C   1 
ATOM   7912  O O   . LEU C 1 230 ? 41.881  -49.712 13.602  1.00 33.41  ? 230 LEU C O   1 
ATOM   7913  C CB  . LEU C 1 230 ? 42.286  -50.126 16.903  1.00 39.88  ? 230 LEU C CB  1 
ATOM   7914  C CG  . LEU C 1 230 ? 42.097  -49.327 18.196  1.00 38.92  ? 230 LEU C CG  1 
ATOM   7915  C CD1 . LEU C 1 230 ? 43.298  -49.440 19.106  1.00 36.17  ? 230 LEU C CD1 1 
ATOM   7916  C CD2 . LEU C 1 230 ? 41.820  -47.870 17.869  1.00 36.88  ? 230 LEU C CD2 1 
ATOM   7917  N N   . TRP C 1 231 ? 41.746  -51.839 14.338  1.00 40.27  ? 231 TRP C N   1 
ATOM   7918  C CA  . TRP C 1 231 ? 42.197  -52.403 13.070  1.00 37.13  ? 231 TRP C CA  1 
ATOM   7919  C C   . TRP C 1 231 ? 41.196  -52.145 11.947  1.00 34.31  ? 231 TRP C C   1 
ATOM   7920  O O   . TRP C 1 231 ? 41.590  -51.909 10.798  1.00 35.89  ? 231 TRP C O   1 
ATOM   7921  C CB  . TRP C 1 231 ? 42.459  -53.901 13.236  1.00 34.26  ? 231 TRP C CB  1 
ATOM   7922  C CG  . TRP C 1 231 ? 43.075  -54.511 12.034  1.00 40.22  ? 231 TRP C CG  1 
ATOM   7923  C CD1 . TRP C 1 231 ? 42.444  -55.249 11.079  1.00 38.64  ? 231 TRP C CD1 1 
ATOM   7924  C CD2 . TRP C 1 231 ? 44.445  -54.419 11.633  1.00 35.53  ? 231 TRP C CD2 1 
ATOM   7925  N NE1 . TRP C 1 231 ? 43.340  -55.632 10.113  1.00 36.52  ? 231 TRP C NE1 1 
ATOM   7926  C CE2 . TRP C 1 231 ? 44.576  -55.133 10.429  1.00 38.47  ? 231 TRP C CE2 1 
ATOM   7927  C CE3 . TRP C 1 231 ? 45.575  -53.805 12.179  1.00 36.68  ? 231 TRP C CE3 1 
ATOM   7928  C CZ2 . TRP C 1 231 ? 45.797  -55.250 9.756   1.00 37.36  ? 231 TRP C CZ2 1 
ATOM   7929  C CZ3 . TRP C 1 231 ? 46.778  -53.920 11.517  1.00 33.40  ? 231 TRP C CZ3 1 
ATOM   7930  C CH2 . TRP C 1 231 ? 46.881  -54.629 10.315  1.00 35.08  ? 231 TRP C CH2 1 
ATOM   7931  N N   . SER C 1 232 ? 39.898  -52.184 12.252  1.00 38.84  ? 232 SER C N   1 
ATOM   7932  C CA  . SER C 1 232 ? 38.887  -51.971 11.214  1.00 42.72  ? 232 SER C CA  1 
ATOM   7933  C C   . SER C 1 232 ? 38.871  -50.525 10.735  1.00 41.53  ? 232 SER C C   1 
ATOM   7934  O O   . SER C 1 232 ? 38.870  -50.257 9.526   1.00 40.94  ? 232 SER C O   1 
ATOM   7935  C CB  . SER C 1 232 ? 37.497  -52.355 11.729  1.00 41.35  ? 232 SER C CB  1 
ATOM   7936  O OG  . SER C 1 232 ? 36.497  -51.872 10.837  1.00 37.77  ? 232 SER C OG  1 
ATOM   7937  N N   . GLN C 1 233 ? 38.837  -49.579 11.672  1.00 40.99  ? 233 GLN C N   1 
ATOM   7938  C CA  . GLN C 1 233 ? 38.710  -48.177 11.301  1.00 41.36  ? 233 GLN C CA  1 
ATOM   7939  C C   . GLN C 1 233 ? 39.997  -47.602 10.717  1.00 44.87  ? 233 GLN C C   1 
ATOM   7940  O O   . GLN C 1 233 ? 39.927  -46.652 9.933   1.00 48.19  ? 233 GLN C O   1 
ATOM   7941  C CB  . GLN C 1 233 ? 38.280  -47.359 12.522  1.00 47.11  ? 233 GLN C CB  1 
ATOM   7942  C CG  . GLN C 1 233 ? 36.801  -47.481 12.916  1.00 47.50  ? 233 GLN C CG  1 
ATOM   7943  C CD  . GLN C 1 233 ? 35.906  -46.462 12.220  1.00 49.67  ? 233 GLN C CD  1 
ATOM   7944  O OE1 . GLN C 1 233 ? 35.343  -46.729 11.157  1.00 44.72  ? 233 GLN C OE1 1 
ATOM   7945  N NE2 . GLN C 1 233 ? 35.782  -45.277 12.817  1.00 55.85  ? 233 GLN C NE2 1 
ATOM   7946  N N   . LEU C 1 234 ? 41.164  -48.156 11.060  1.00 41.81  ? 234 LEU C N   1 
ATOM   7947  C CA  . LEU C 1 234 ? 42.446  -47.548 10.710  1.00 39.36  ? 234 LEU C CA  1 
ATOM   7948  C C   . LEU C 1 234 ? 43.174  -48.244 9.563   1.00 38.58  ? 234 LEU C C   1 
ATOM   7949  O O   . LEU C 1 234 ? 44.267  -47.805 9.185   1.00 40.31  ? 234 LEU C O   1 
ATOM   7950  C CB  . LEU C 1 234 ? 43.349  -47.499 11.948  1.00 37.44  ? 234 LEU C CB  1 
ATOM   7951  C CG  . LEU C 1 234 ? 42.810  -46.653 13.108  1.00 43.19  ? 234 LEU C CG  1 
ATOM   7952  C CD1 . LEU C 1 234 ? 43.779  -46.615 14.297  1.00 32.30  ? 234 LEU C CD1 1 
ATOM   7953  C CD2 . LEU C 1 234 ? 42.459  -45.234 12.637  1.00 40.04  ? 234 LEU C CD2 1 
ATOM   7954  N N   . THR C 1 235 ? 42.600  -49.298 8.989   1.00 38.10  ? 235 THR C N   1 
ATOM   7955  C CA  . THR C 1 235 ? 43.182  -50.024 7.871   1.00 36.64  ? 235 THR C CA  1 
ATOM   7956  C C   . THR C 1 235 ? 42.236  -50.019 6.680   1.00 41.49  ? 235 THR C C   1 
ATOM   7957  O O   . THR C 1 235 ? 41.043  -49.742 6.808   1.00 38.66  ? 235 THR C O   1 
ATOM   7958  C CB  . THR C 1 235 ? 43.498  -51.488 8.232   1.00 37.94  ? 235 THR C CB  1 
ATOM   7959  O OG1 . THR C 1 235 ? 42.287  -52.163 8.614   1.00 37.07  ? 235 THR C OG1 1 
ATOM   7960  C CG2 . THR C 1 235 ? 44.507  -51.563 9.364   1.00 36.41  ? 235 THR C CG2 1 
ATOM   7961  N N   . ASP C 1 236 ? 42.787  -50.352 5.517   1.00 45.68  ? 236 ASP C N   1 
ATOM   7962  C CA  . ASP C 1 236 ? 41.999  -50.477 4.296   1.00 46.02  ? 236 ASP C CA  1 
ATOM   7963  C C   . ASP C 1 236 ? 42.748  -51.419 3.349   1.00 45.94  ? 236 ASP C C   1 
ATOM   7964  O O   . ASP C 1 236 ? 43.656  -52.141 3.773   1.00 49.37  ? 236 ASP C O   1 
ATOM   7965  C CB  . ASP C 1 236 ? 41.692  -49.085 3.701   1.00 44.68  ? 236 ASP C CB  1 
ATOM   7966  C CG  . ASP C 1 236 ? 42.949  -48.310 3.237   1.00 47.89  ? 236 ASP C CG  1 
ATOM   7967  O OD1 . ASP C 1 236 ? 43.947  -48.921 2.775   1.00 42.41  ? 236 ASP C OD1 1 
ATOM   7968  O OD2 . ASP C 1 236 ? 42.914  -47.059 3.314   1.00 45.76  ? 236 ASP C OD2 1 
ATOM   7969  N N   . THR C 1 237 ? 42.372  -51.399 2.065   1.00 43.79  ? 237 THR C N   1 
ATOM   7970  C CA  . THR C 1 237 ? 42.871  -52.393 1.110   1.00 46.78  ? 237 THR C CA  1 
ATOM   7971  C C   . THR C 1 237 ? 44.382  -52.282 0.919   1.00 51.01  ? 237 THR C C   1 
ATOM   7972  O O   . THR C 1 237 ? 45.097  -53.293 0.908   1.00 45.16  ? 237 THR C O   1 
ATOM   7973  C CB  . THR C 1 237 ? 42.156  -52.233 -0.239  1.00 45.31  ? 237 THR C CB  1 
ATOM   7974  O OG1 . THR C 1 237 ? 40.747  -52.401 -0.063  1.00 50.99  ? 237 THR C OG1 1 
ATOM   7975  C CG2 . THR C 1 237 ? 42.651  -53.252 -1.258  1.00 43.55  ? 237 THR C CG2 1 
ATOM   7976  N N   . GLN C 1 238 ? 44.885  -51.059 0.742   1.00 49.27  ? 238 GLN C N   1 
ATOM   7977  C CA  . GLN C 1 238 ? 46.297  -50.827 0.481   1.00 46.70  ? 238 GLN C CA  1 
ATOM   7978  C C   . GLN C 1 238 ? 47.068  -50.412 1.724   1.00 45.73  ? 238 GLN C C   1 
ATOM   7979  O O   . GLN C 1 238 ? 48.248  -50.075 1.620   1.00 44.73  ? 238 GLN C O   1 
ATOM   7980  C CB  . GLN C 1 238 ? 46.463  -49.779 -0.619  1.00 48.25  ? 238 GLN C CB  1 
ATOM   7981  C CG  . GLN C 1 238 ? 45.647  -50.088 -1.854  1.00 55.73  ? 238 GLN C CG  1 
ATOM   7982  C CD  . GLN C 1 238 ? 44.419  -49.208 -1.973  1.00 48.79  ? 238 GLN C CD  1 
ATOM   7983  O OE1 . GLN C 1 238 ? 44.429  -48.054 -1.555  1.00 53.26  ? 238 GLN C OE1 1 
ATOM   7984  N NE2 . GLN C 1 238 ? 43.338  -49.772 -2.503  1.00 45.08  ? 238 GLN C NE2 1 
ATOM   7985  N N   . ASN C 1 239 ? 46.435  -50.446 2.894   1.00 43.62  ? 239 ASN C N   1 
ATOM   7986  C CA  . ASN C 1 239 ? 47.056  -50.049 4.157   1.00 40.34  ? 239 ASN C CA  1 
ATOM   7987  C C   . ASN C 1 239 ? 46.815  -51.150 5.180   1.00 41.52  ? 239 ASN C C   1 
ATOM   7988  O O   . ASN C 1 239 ? 45.798  -51.165 5.880   1.00 40.64  ? 239 ASN C O   1 
ATOM   7989  C CB  . ASN C 1 239 ? 46.509  -48.729 4.641   1.00 43.19  ? 239 ASN C CB  1 
ATOM   7990  C CG  . ASN C 1 239 ? 47.510  -47.619 4.534   1.00 51.62  ? 239 ASN C CG  1 
ATOM   7991  O OD1 . ASN C 1 239 ? 48.509  -47.722 3.807   1.00 47.61  ? 239 ASN C OD1 1 
ATOM   7992  N ND2 . ASN C 1 239 ? 47.262  -46.537 5.274   1.00 54.93  ? 239 ASN C ND2 1 
ATOM   7993  N N   . GLN C 1 240 ? 47.748  -52.082 5.271   1.00 40.00  ? 240 GLN C N   1 
ATOM   7994  C CA  . GLN C 1 240 ? 47.599  -53.196 6.191   1.00 40.15  ? 240 GLN C CA  1 
ATOM   7995  C C   . GLN C 1 240 ? 48.578  -53.090 7.353   1.00 38.46  ? 240 GLN C C   1 
ATOM   7996  O O   . GLN C 1 240 ? 48.948  -54.103 7.951   1.00 32.67  ? 240 GLN C O   1 
ATOM   7997  C CB  . GLN C 1 240 ? 47.759  -54.526 5.457   1.00 36.39  ? 240 GLN C CB  1 
ATOM   7998  C CG  . GLN C 1 240 ? 46.712  -55.581 5.821   1.00 46.91  ? 240 GLN C CG  1 
ATOM   7999  C CD  . GLN C 1 240 ? 45.393  -55.369 5.110   1.00 45.87  ? 240 GLN C CD  1 
ATOM   8000  O OE1 . GLN C 1 240 ? 45.367  -55.075 3.919   1.00 50.84  ? 240 GLN C OE1 1 
ATOM   8001  N NE2 . GLN C 1 240 ? 44.294  -55.530 5.831   1.00 44.01  ? 240 GLN C NE2 1 
ATOM   8002  N N   . PHE C 1 241 ? 49.011  -51.868 7.674   1.00 32.74  ? 241 PHE C N   1 
ATOM   8003  C CA  . PHE C 1 241 ? 49.826  -51.610 8.852   1.00 32.99  ? 241 PHE C CA  1 
ATOM   8004  C C   . PHE C 1 241 ? 49.122  -50.603 9.745   1.00 33.51  ? 241 PHE C C   1 
ATOM   8005  O O   . PHE C 1 241 ? 48.503  -49.653 9.256   1.00 33.53  ? 241 PHE C O   1 
ATOM   8006  C CB  . PHE C 1 241 ? 51.221  -51.054 8.501   1.00 37.60  ? 241 PHE C CB  1 
ATOM   8007  C CG  . PHE C 1 241 ? 52.158  -52.065 7.880   1.00 36.15  ? 241 PHE C CG  1 
ATOM   8008  C CD1 . PHE C 1 241 ? 52.105  -53.401 8.245   1.00 32.22  ? 241 PHE C CD1 1 
ATOM   8009  C CD2 . PHE C 1 241 ? 53.091  -51.668 6.936   1.00 36.14  ? 241 PHE C CD2 1 
ATOM   8010  C CE1 . PHE C 1 241 ? 52.960  -54.326 7.683   1.00 33.56  ? 241 PHE C CE1 1 
ATOM   8011  C CE2 . PHE C 1 241 ? 53.952  -52.589 6.362   1.00 39.14  ? 241 PHE C CE2 1 
ATOM   8012  C CZ  . PHE C 1 241 ? 53.887  -53.924 6.735   1.00 35.67  ? 241 PHE C CZ  1 
ATOM   8013  N N   . ILE C 1 242 ? 49.255  -50.791 11.049  1.00 24.66  ? 242 ILE C N   1 
ATOM   8014  C CA  . ILE C 1 242 ? 48.883  -49.783 12.030  1.00 36.25  ? 242 ILE C CA  1 
ATOM   8015  C C   . ILE C 1 242 ? 50.107  -49.489 12.872  1.00 36.64  ? 242 ILE C C   1 
ATOM   8016  O O   . ILE C 1 242 ? 50.862  -50.404 13.224  1.00 34.64  ? 242 ILE C O   1 
ATOM   8017  C CB  . ILE C 1 242 ? 47.700  -50.234 12.913  1.00 31.67  ? 242 ILE C CB  1 
ATOM   8018  C CG1 . ILE C 1 242 ? 46.457  -50.298 12.049  1.00 36.60  ? 242 ILE C CG1 1 
ATOM   8019  C CG2 . ILE C 1 242 ? 47.460  -49.268 14.031  1.00 35.33  ? 242 ILE C CG2 1 
ATOM   8020  C CD1 . ILE C 1 242 ? 46.311  -49.104 11.181  1.00 34.88  ? 242 ILE C CD1 1 
ATOM   8021  N N   . THR C 1 243 ? 50.334  -48.215 13.156  1.00 29.77  ? 243 THR C N   1 
ATOM   8022  C CA  . THR C 1 243 ? 51.328  -47.869 14.151  1.00 32.63  ? 243 THR C CA  1 
ATOM   8023  C C   . THR C 1 243 ? 50.615  -47.778 15.490  1.00 29.21  ? 243 THR C C   1 
ATOM   8024  O O   . THR C 1 243 ? 49.461  -47.344 15.553  1.00 31.92  ? 243 THR C O   1 
ATOM   8025  C CB  . THR C 1 243 ? 52.057  -46.568 13.779  1.00 33.69  ? 243 THR C CB  1 
ATOM   8026  O OG1 . THR C 1 243 ? 53.239  -46.434 14.569  1.00 38.26  ? 243 THR C OG1 1 
ATOM   8027  C CG2 . THR C 1 243 ? 51.207  -45.384 14.019  1.00 28.44  ? 243 THR C CG2 1 
ATOM   8028  N N   . VAL C 1 244 ? 51.259  -48.294 16.541  1.00 22.69  ? 244 VAL C N   1 
ATOM   8029  C CA  . VAL C 1 244 ? 50.738  -48.218 17.903  1.00 24.12  ? 244 VAL C CA  1 
ATOM   8030  C C   . VAL C 1 244 ? 51.886  -47.793 18.790  1.00 24.72  ? 244 VAL C C   1 
ATOM   8031  O O   . VAL C 1 244 ? 52.942  -48.426 18.762  1.00 22.93  ? 244 VAL C O   1 
ATOM   8032  C CB  . VAL C 1 244 ? 50.158  -49.561 18.398  1.00 30.80  ? 244 VAL C CB  1 
ATOM   8033  C CG1 . VAL C 1 244 ? 49.656  -49.424 19.821  1.00 17.87  ? 244 VAL C CG1 1 
ATOM   8034  C CG2 . VAL C 1 244 ? 49.045  -50.089 17.468  1.00 30.29  ? 244 VAL C CG2 1 
ATOM   8035  N N   . GLU C 1 245 ? 51.705  -46.716 19.557  1.00 30.66  ? 245 GLU C N   1 
ATOM   8036  C CA  . GLU C 1 245 ? 52.846  -46.116 20.242  1.00 31.98  ? 245 GLU C CA  1 
ATOM   8037  C C   . GLU C 1 245 ? 52.473  -45.610 21.624  1.00 32.14  ? 245 GLU C C   1 
ATOM   8038  O O   . GLU C 1 245 ? 51.349  -45.168 21.856  1.00 33.32  ? 245 GLU C O   1 
ATOM   8039  C CB  . GLU C 1 245 ? 53.438  -44.944 19.442  1.00 29.93  ? 245 GLU C CB  1 
ATOM   8040  C CG  . GLU C 1 245 ? 53.533  -45.198 17.952  1.00 29.18  ? 245 GLU C CG  1 
ATOM   8041  C CD  . GLU C 1 245 ? 54.074  -44.012 17.195  1.00 33.83  ? 245 GLU C CD  1 
ATOM   8042  O OE1 . GLU C 1 245 ? 53.462  -42.926 17.276  1.00 35.10  ? 245 GLU C OE1 1 
ATOM   8043  O OE2 . GLU C 1 245 ? 55.100  -44.163 16.505  1.00 32.49  ? 245 GLU C OE2 1 
ATOM   8044  N N   . THR C 1 246 ? 53.456  -45.649 22.526  1.00 30.04  ? 246 THR C N   1 
ATOM   8045  C CA  . THR C 1 246 ? 53.356  -44.914 23.773  1.00 31.71  ? 246 THR C CA  1 
ATOM   8046  C C   . THR C 1 246 ? 53.196  -43.431 23.462  1.00 34.73  ? 246 THR C C   1 
ATOM   8047  O O   . THR C 1 246 ? 53.882  -42.889 22.592  1.00 29.33  ? 246 THR C O   1 
ATOM   8048  C CB  . THR C 1 246 ? 54.603  -45.147 24.645  1.00 33.34  ? 246 THR C CB  1 
ATOM   8049  O OG1 . THR C 1 246 ? 54.675  -46.522 25.055  1.00 36.96  ? 246 THR C OG1 1 
ATOM   8050  C CG2 . THR C 1 246 ? 54.571  -44.260 25.890  1.00 34.72  ? 246 THR C CG2 1 
ATOM   8051  N N   . TYR C 1 247 ? 52.275  -42.782 24.177  1.00 33.90  ? 247 TYR C N   1 
ATOM   8052  C CA  . TYR C 1 247 ? 51.948  -41.369 24.005  1.00 35.01  ? 247 TYR C CA  1 
ATOM   8053  C C   . TYR C 1 247 ? 52.375  -40.595 25.254  1.00 38.67  ? 247 TYR C C   1 
ATOM   8054  O O   . TYR C 1 247 ? 51.916  -40.892 26.361  1.00 36.72  ? 247 TYR C O   1 
ATOM   8055  C CB  . TYR C 1 247 ? 50.450  -41.203 23.744  1.00 36.52  ? 247 TYR C CB  1 
ATOM   8056  C CG  . TYR C 1 247 ? 50.052  -39.794 23.405  1.00 42.38  ? 247 TYR C CG  1 
ATOM   8057  C CD1 . TYR C 1 247 ? 49.781  -38.870 24.403  1.00 41.32  ? 247 TYR C CD1 1 
ATOM   8058  C CD2 . TYR C 1 247 ? 49.964  -39.383 22.084  1.00 40.97  ? 247 TYR C CD2 1 
ATOM   8059  C CE1 . TYR C 1 247 ? 49.428  -37.577 24.091  1.00 47.47  ? 247 TYR C CE1 1 
ATOM   8060  C CE2 . TYR C 1 247 ? 49.614  -38.091 21.762  1.00 43.74  ? 247 TYR C CE2 1 
ATOM   8061  C CZ  . TYR C 1 247 ? 49.351  -37.190 22.770  1.00 46.69  ? 247 TYR C CZ  1 
ATOM   8062  O OH  . TYR C 1 247 ? 48.992  -35.897 22.455  1.00 50.14  ? 247 TYR C OH  1 
ATOM   8063  N N   . HIS C 1 248 ? 53.246  -39.610 25.078  1.00 35.00  ? 248 HIS C N   1 
ATOM   8064  C CA  . HIS C 1 248 ? 53.748  -38.809 26.188  1.00 40.86  ? 248 HIS C CA  1 
ATOM   8065  C C   . HIS C 1 248 ? 53.024  -37.468 26.246  1.00 39.57  ? 248 HIS C C   1 
ATOM   8066  O O   . HIS C 1 248 ? 52.334  -37.077 25.309  1.00 44.21  ? 248 HIS C O   1 
ATOM   8067  C CB  . HIS C 1 248 ? 55.255  -38.612 26.052  1.00 37.19  ? 248 HIS C CB  1 
ATOM   8068  C CG  . HIS C 1 248 ? 56.019  -39.897 25.992  1.00 42.56  ? 248 HIS C CG  1 
ATOM   8069  N ND1 . HIS C 1 248 ? 56.898  -40.290 26.978  1.00 40.56  ? 248 HIS C ND1 1 
ATOM   8070  C CD2 . HIS C 1 248 ? 56.021  -40.888 25.070  1.00 36.40  ? 248 HIS C CD2 1 
ATOM   8071  C CE1 . HIS C 1 248 ? 57.413  -41.462 26.660  1.00 39.80  ? 248 HIS C CE1 1 
ATOM   8072  N NE2 . HIS C 1 248 ? 56.895  -41.848 25.510  1.00 35.37  ? 248 HIS C NE2 1 
ATOM   8073  N N   . ARG C 1 249 ? 53.198  -36.751 27.364  1.00 48.78  ? 249 ARG C N   1 
ATOM   8074  C CA  . ARG C 1 249 ? 52.396  -35.548 27.603  1.00 46.11  ? 249 ARG C CA  1 
ATOM   8075  C C   . ARG C 1 249 ? 52.799  -34.397 26.685  1.00 44.91  ? 249 ARG C C   1 
ATOM   8076  O O   . ARG C 1 249 ? 51.934  -33.756 26.076  1.00 55.59  ? 249 ARG C O   1 
ATOM   8077  C CB  . ARG C 1 249 ? 52.485  -35.104 29.069  1.00 51.06  ? 249 ARG C CB  1 
ATOM   8078  C CG  . ARG C 1 249 ? 51.234  -34.327 29.515  1.00 51.85  ? 249 ARG C CG  1 
ATOM   8079  C CD  . ARG C 1 249 ? 51.429  -33.428 30.744  1.00 55.29  ? 249 ARG C CD  1 
ATOM   8080  N NE  . ARG C 1 249 ? 52.674  -32.662 30.762  1.00 62.53  ? 249 ARG C NE  1 
ATOM   8081  C CZ  . ARG C 1 249 ? 52.782  -31.365 30.482  1.00 64.25  ? 249 ARG C CZ  1 
ATOM   8082  N NH1 . ARG C 1 249 ? 51.741  -30.649 30.076  1.00 60.15  ? 249 ARG C NH1 1 
ATOM   8083  N NH2 . ARG C 1 249 ? 53.966  -30.770 30.617  1.00 62.78  ? 249 ARG C NH2 1 
ATOM   8084  N N   . ALA C 1 250 ? 54.100  -34.100 26.601  1.00 42.55  ? 250 ALA C N   1 
ATOM   8085  C CA  . ALA C 1 250 ? 54.678  -33.024 25.784  1.00 44.19  ? 250 ALA C CA  1 
ATOM   8086  C C   . ALA C 1 250 ? 54.449  -31.619 26.345  1.00 47.62  ? 250 ALA C C   1 
ATOM   8087  O O   . ALA C 1 250 ? 53.330  -31.089 26.324  1.00 44.91  ? 250 ALA C O   1 
ATOM   8088  C CB  . ALA C 1 250 ? 54.166  -33.066 24.337  1.00 41.52  ? 250 ALA C CB  1 
ATOM   8089  N N   . ASP C 1 251 ? 55.533  -30.998 26.814  1.00 44.84  ? 251 ASP C N   1 
ATOM   8090  C CA  . ASP C 1 251 ? 55.508  -29.592 27.202  1.00 48.85  ? 251 ASP C CA  1 
ATOM   8091  C C   . ASP C 1 251 ? 55.651  -28.675 25.983  1.00 46.11  ? 251 ASP C C   1 
ATOM   8092  O O   . ASP C 1 251 ? 54.991  -27.632 25.907  1.00 48.31  ? 251 ASP C O   1 
ATOM   8093  C CB  . ASP C 1 251 ? 56.604  -29.352 28.249  1.00 51.31  ? 251 ASP C CB  1 
ATOM   8094  C CG  . ASP C 1 251 ? 56.986  -27.894 28.398  1.00 53.30  ? 251 ASP C CG  1 
ATOM   8095  O OD1 . ASP C 1 251 ? 56.086  -27.025 28.415  1.00 60.80  ? 251 ASP C OD1 1 
ATOM   8096  O OD2 . ASP C 1 251 ? 58.204  -27.626 28.526  1.00 58.86  ? 251 ASP C OD2 1 
ATOM   8097  N N   . GLN C 1 252 ? 56.476  -29.059 25.009  1.00 40.50  ? 252 GLN C N   1 
ATOM   8098  C CA  . GLN C 1 252 ? 56.589  -28.357 23.734  1.00 37.02  ? 252 GLN C CA  1 
ATOM   8099  C C   . GLN C 1 252 ? 56.234  -29.307 22.597  1.00 34.93  ? 252 GLN C C   1 
ATOM   8100  O O   . GLN C 1 252 ? 56.670  -30.463 22.586  1.00 36.27  ? 252 GLN C O   1 
ATOM   8101  C CB  . GLN C 1 252 ? 58.008  -27.805 23.521  1.00 36.98  ? 252 GLN C CB  1 
ATOM   8102  C CG  . GLN C 1 252 ? 58.704  -27.354 24.799  1.00 41.08  ? 252 GLN C CG  1 
ATOM   8103  C CD  . GLN C 1 252 ? 60.221  -27.311 24.673  1.00 45.23  ? 252 GLN C CD  1 
ATOM   8104  O OE1 . GLN C 1 252 ? 60.773  -26.992 23.613  1.00 41.93  ? 252 GLN C OE1 1 
ATOM   8105  N NE2 . GLN C 1 252 ? 60.908  -27.632 25.770  1.00 50.09  ? 252 GLN C NE2 1 
ATOM   8106  N N   . ARG C 1 253 ? 55.438  -28.824 21.653  1.00 33.82  ? 253 ARG C N   1 
ATOM   8107  C CA  . ARG C 1 253 ? 55.230  -29.478 20.374  1.00 34.15  ? 253 ARG C CA  1 
ATOM   8108  C C   . ARG C 1 253 ? 55.779  -28.557 19.299  1.00 32.66  ? 253 ARG C C   1 
ATOM   8109  O O   . ARG C 1 253 ? 55.817  -27.340 19.481  1.00 31.61  ? 253 ARG C O   1 
ATOM   8110  C CB  . ARG C 1 253 ? 53.747  -29.771 20.106  1.00 36.00  ? 253 ARG C CB  1 
ATOM   8111  C CG  . ARG C 1 253 ? 53.028  -30.401 21.288  1.00 42.91  ? 253 ARG C CG  1 
ATOM   8112  C CD  . ARG C 1 253 ? 51.501  -30.427 21.125  1.00 46.90  ? 253 ARG C CD  1 
ATOM   8113  N NE  . ARG C 1 253 ? 50.977  -31.723 21.546  1.00 53.64  ? 253 ARG C NE  1 
ATOM   8114  C CZ  . ARG C 1 253 ? 50.780  -32.082 22.811  1.00 59.19  ? 253 ARG C CZ  1 
ATOM   8115  N NH1 . ARG C 1 253 ? 50.977  -31.235 23.813  1.00 53.91  ? 253 ARG C NH1 1 
ATOM   8116  N NH2 . ARG C 1 253 ? 50.386  -33.326 23.080  1.00 52.65  ? 253 ARG C NH2 1 
ATOM   8117  N N   . PHE C 1 254 ? 56.185  -29.141 18.172  1.00 29.64  ? 254 PHE C N   1 
ATOM   8118  C CA  . PHE C 1 254 ? 56.892  -28.387 17.148  1.00 24.66  ? 254 PHE C CA  1 
ATOM   8119  C C   . PHE C 1 254 ? 56.983  -29.233 15.893  1.00 21.94  ? 254 PHE C C   1 
ATOM   8120  O O   . PHE C 1 254 ? 56.882  -30.456 15.944  1.00 26.69  ? 254 PHE C O   1 
ATOM   8121  C CB  . PHE C 1 254 ? 58.301  -28.000 17.603  1.00 29.39  ? 254 PHE C CB  1 
ATOM   8122  C CG  . PHE C 1 254 ? 59.246  -29.171 17.693  1.00 24.14  ? 254 PHE C CG  1 
ATOM   8123  C CD1 . PHE C 1 254 ? 59.906  -29.637 16.565  1.00 26.24  ? 254 PHE C CD1 1 
ATOM   8124  C CD2 . PHE C 1 254 ? 59.487  -29.783 18.898  1.00 25.16  ? 254 PHE C CD2 1 
ATOM   8125  C CE1 . PHE C 1 254 ? 60.778  -30.719 16.642  1.00 29.07  ? 254 PHE C CE1 1 
ATOM   8126  C CE2 . PHE C 1 254 ? 60.362  -30.853 18.989  1.00 29.04  ? 254 PHE C CE2 1 
ATOM   8127  C CZ  . PHE C 1 254 ? 61.001  -31.331 17.862  1.00 27.65  ? 254 PHE C CZ  1 
ATOM   8128  N N   . PHE C 1 255 ? 57.196  -28.563 14.768  1.00 25.08  ? 255 PHE C N   1 
ATOM   8129  C CA  . PHE C 1 255 ? 57.700  -29.235 13.584  1.00 27.77  ? 255 PHE C CA  1 
ATOM   8130  C C   . PHE C 1 255 ? 58.684  -28.316 12.882  1.00 22.55  ? 255 PHE C C   1 
ATOM   8131  O O   . PHE C 1 255 ? 58.646  -27.096 13.042  1.00 23.58  ? 255 PHE C O   1 
ATOM   8132  C CB  . PHE C 1 255 ? 56.568  -29.715 12.643  1.00 29.42  ? 255 PHE C CB  1 
ATOM   8133  C CG  . PHE C 1 255 ? 55.865  -28.627 11.870  1.00 23.03  ? 255 PHE C CG  1 
ATOM   8134  C CD1 . PHE C 1 255 ? 56.323  -28.222 10.628  1.00 22.43  ? 255 PHE C CD1 1 
ATOM   8135  C CD2 . PHE C 1 255 ? 54.703  -28.056 12.364  1.00 24.67  ? 255 PHE C CD2 1 
ATOM   8136  C CE1 . PHE C 1 255 ? 55.643  -27.225 9.901   1.00 21.80  ? 255 PHE C CE1 1 
ATOM   8137  C CE2 . PHE C 1 255 ? 54.035  -27.077 11.661  1.00 20.79  ? 255 PHE C CE2 1 
ATOM   8138  C CZ  . PHE C 1 255 ? 54.500  -26.669 10.417  1.00 19.28  ? 255 PHE C CZ  1 
ATOM   8139  N N   . PHE C 1 256 ? 59.597  -28.934 12.153  1.00 20.84  ? 256 PHE C N   1 
ATOM   8140  C CA  . PHE C 1 256 ? 60.611  -28.268 11.349  1.00 24.16  ? 256 PHE C CA  1 
ATOM   8141  C C   . PHE C 1 256 ? 60.333  -28.539 9.875   1.00 19.31  ? 256 PHE C C   1 
ATOM   8142  O O   . PHE C 1 256 ? 60.027  -29.673 9.510   1.00 19.59  ? 256 PHE C O   1 
ATOM   8143  C CB  . PHE C 1 256 ? 62.015  -28.798 11.684  1.00 19.94  ? 256 PHE C CB  1 
ATOM   8144  C CG  . PHE C 1 256 ? 62.425  -28.646 13.128  1.00 22.31  ? 256 PHE C CG  1 
ATOM   8145  C CD1 . PHE C 1 256 ? 61.751  -27.789 13.993  1.00 23.39  ? 256 PHE C CD1 1 
ATOM   8146  C CD2 . PHE C 1 256 ? 63.537  -29.331 13.602  1.00 18.36  ? 256 PHE C CD2 1 
ATOM   8147  C CE1 . PHE C 1 256 ? 62.160  -27.660 15.315  1.00 28.60  ? 256 PHE C CE1 1 
ATOM   8148  C CE2 . PHE C 1 256 ? 63.961  -29.192 14.907  1.00 25.00  ? 256 PHE C CE2 1 
ATOM   8149  C CZ  . PHE C 1 256 ? 63.281  -28.367 15.772  1.00 25.07  ? 256 PHE C CZ  1 
ATOM   8150  N N   . GLU C 1 257 ? 60.467  -27.517 9.026   1.00 19.05  ? 257 GLU C N   1 
ATOM   8151  C CA  . GLU C 1 257 ? 60.257  -27.650 7.585   1.00 22.21  ? 257 GLU C CA  1 
ATOM   8152  C C   . GLU C 1 257 ? 61.543  -27.354 6.821   1.00 21.96  ? 257 GLU C C   1 
ATOM   8153  O O   . GLU C 1 257 ? 62.235  -26.373 7.109   1.00 24.83  ? 257 GLU C O   1 
ATOM   8154  C CB  . GLU C 1 257 ? 59.151  -26.704 7.084   1.00 22.23  ? 257 GLU C CB  1 
ATOM   8155  C CG  . GLU C 1 257 ? 58.806  -26.911 5.615   1.00 22.00  ? 257 GLU C CG  1 
ATOM   8156  C CD  . GLU C 1 257 ? 57.352  -26.618 5.309   1.00 25.26  ? 257 GLU C CD  1 
ATOM   8157  O OE1 . GLU C 1 257 ? 56.765  -25.790 6.048   1.00 24.74  ? 257 GLU C OE1 1 
ATOM   8158  O OE2 . GLU C 1 257 ? 56.799  -27.210 4.339   1.00 19.58  ? 257 GLU C OE2 1 
ATOM   8159  N N   . TYR C 1 258 ? 61.839  -28.179 5.823   1.00 21.00  ? 258 TYR C N   1 
ATOM   8160  C CA  . TYR C 1 258 ? 63.085  -28.087 5.075   1.00 20.37  ? 258 TYR C CA  1 
ATOM   8161  C C   . TYR C 1 258 ? 62.811  -28.006 3.577   1.00 20.95  ? 258 TYR C C   1 
ATOM   8162  O O   . TYR C 1 258 ? 61.780  -28.467 3.087   1.00 23.81  ? 258 TYR C O   1 
ATOM   8163  C CB  . TYR C 1 258 ? 63.996  -29.312 5.362   1.00 23.15  ? 258 TYR C CB  1 
ATOM   8164  C CG  . TYR C 1 258 ? 64.350  -29.484 6.814   1.00 20.77  ? 258 TYR C CG  1 
ATOM   8165  C CD1 . TYR C 1 258 ? 63.453  -30.060 7.707   1.00 23.72  ? 258 TYR C CD1 1 
ATOM   8166  C CD2 . TYR C 1 258 ? 65.573  -29.053 7.301   1.00 24.20  ? 258 TYR C CD2 1 
ATOM   8167  C CE1 . TYR C 1 258 ? 63.780  -30.200 9.053   1.00 22.28  ? 258 TYR C CE1 1 
ATOM   8168  C CE2 . TYR C 1 258 ? 65.905  -29.185 8.645   1.00 20.64  ? 258 TYR C CE2 1 
ATOM   8169  C CZ  . TYR C 1 258 ? 65.005  -29.760 9.506   1.00 22.31  ? 258 TYR C CZ  1 
ATOM   8170  O OH  . TYR C 1 258 ? 65.340  -29.879 10.829  1.00 25.82  ? 258 TYR C OH  1 
ATOM   8171  N N   . HIS C 1 259 ? 63.763  -27.455 2.828   1.00 23.85  ? 259 HIS C N   1 
ATOM   8172  C CA  . HIS C 1 259 ? 63.775  -27.642 1.379   1.00 25.16  ? 259 HIS C CA  1 
ATOM   8173  C C   . HIS C 1 259 ? 65.025  -28.419 0.984   1.00 24.09  ? 259 HIS C C   1 
ATOM   8174  O O   . HIS C 1 259 ? 66.145  -28.049 1.362   1.00 21.46  ? 259 HIS C O   1 
ATOM   8175  C CB  . HIS C 1 259 ? 63.708  -26.315 0.627   1.00 25.41  ? 259 HIS C CB  1 
ATOM   8176  C CG  . HIS C 1 259 ? 63.882  -26.462 -0.850  1.00 26.37  ? 259 HIS C CG  1 
ATOM   8177  N ND1 . HIS C 1 259 ? 65.114  -26.393 -1.468  1.00 28.82  ? 259 HIS C ND1 1 
ATOM   8178  C CD2 . HIS C 1 259 ? 62.980  -26.684 -1.835  1.00 28.10  ? 259 HIS C CD2 1 
ATOM   8179  C CE1 . HIS C 1 259 ? 64.963  -26.566 -2.770  1.00 26.97  ? 259 HIS C CE1 1 
ATOM   8180  N NE2 . HIS C 1 259 ? 63.678  -26.746 -3.019  1.00 26.61  ? 259 HIS C NE2 1 
ATOM   8181  N N   . LEU C 1 260 ? 64.823  -29.504 0.244   1.00 22.56  ? 260 LEU C N   1 
ATOM   8182  C CA  . LEU C 1 260 ? 65.878  -30.452 -0.098  1.00 27.46  ? 260 LEU C CA  1 
ATOM   8183  C C   . LEU C 1 260 ? 66.139  -30.393 -1.601  1.00 26.49  ? 260 LEU C C   1 
ATOM   8184  O O   . LEU C 1 260 ? 65.193  -30.451 -2.396  1.00 28.28  ? 260 LEU C O   1 
ATOM   8185  C CB  . LEU C 1 260 ? 65.482  -31.885 0.326   1.00 27.86  ? 260 LEU C CB  1 
ATOM   8186  C CG  . LEU C 1 260 ? 65.739  -32.315 1.782   1.00 27.88  ? 260 LEU C CG  1 
ATOM   8187  C CD1 . LEU C 1 260 ? 65.019  -31.373 2.745   1.00 21.65  ? 260 LEU C CD1 1 
ATOM   8188  C CD2 . LEU C 1 260 ? 65.339  -33.766 2.065   1.00 23.86  ? 260 LEU C CD2 1 
ATOM   8189  N N   . ASP C 1 261 ? 67.408  -30.261 -1.985  1.00 24.48  ? 261 ASP C N   1 
ATOM   8190  C CA  . ASP C 1 261 ? 67.818  -30.394 -3.384  1.00 24.47  ? 261 ASP C CA  1 
ATOM   8191  C C   . ASP C 1 261 ? 69.114  -31.208 -3.438  1.00 27.11  ? 261 ASP C C   1 
ATOM   8192  O O   . ASP C 1 261 ? 69.538  -31.818 -2.450  1.00 28.23  ? 261 ASP C O   1 
ATOM   8193  C CB  . ASP C 1 261 ? 67.944  -29.016 -4.062  1.00 25.13  ? 261 ASP C CB  1 
ATOM   8194  C CG  . ASP C 1 261 ? 69.073  -28.147 -3.485  1.00 30.67  ? 261 ASP C CG  1 
ATOM   8195  O OD1 . ASP C 1 261 ? 70.056  -28.664 -2.901  1.00 30.20  ? 261 ASP C OD1 1 
ATOM   8196  O OD2 . ASP C 1 261 ? 68.976  -26.906 -3.632  1.00 38.44  ? 261 ASP C OD2 1 
ATOM   8197  N N   . GLY C 1 262 ? 69.774  -31.191 -4.594  1.00 27.20  ? 262 GLY C N   1 
ATOM   8198  C CA  . GLY C 1 262 ? 70.959  -32.016 -4.798  1.00 26.51  ? 262 GLY C CA  1 
ATOM   8199  C C   . GLY C 1 262 ? 72.183  -31.629 -3.974  1.00 27.65  ? 262 GLY C C   1 
ATOM   8200  O O   . GLY C 1 262 ? 73.136  -32.410 -3.941  1.00 29.34  ? 262 GLY C O   1 
ATOM   8201  N N   . ASP C 1 263 ? 72.205  -30.460 -3.333  1.00 25.70  ? 263 ASP C N   1 
ATOM   8202  C CA  . ASP C 1 263 ? 73.352  -30.087 -2.508  1.00 29.92  ? 263 ASP C CA  1 
ATOM   8203  C C   . ASP C 1 263 ? 73.095  -30.066 -1.016  1.00 29.95  ? 263 ASP C C   1 
ATOM   8204  O O   . ASP C 1 263 ? 74.054  -30.137 -0.250  1.00 31.61  ? 263 ASP C O   1 
ATOM   8205  C CB  . ASP C 1 263 ? 73.847  -28.687 -2.851  1.00 38.12  ? 263 ASP C CB  1 
ATOM   8206  C CG  . ASP C 1 263 ? 73.912  -28.443 -4.320  1.00 44.50  ? 263 ASP C CG  1 
ATOM   8207  O OD1 . ASP C 1 263 ? 74.258  -29.353 -5.107  1.00 40.74  ? 263 ASP C OD1 1 
ATOM   8208  O OD2 . ASP C 1 263 ? 73.575  -27.310 -4.701  1.00 47.40  ? 263 ASP C OD2 1 
ATOM   8209  N N   . ARG C 1 264 ? 71.855  -29.878 -0.575  1.00 28.80  ? 264 ARG C N   1 
ATOM   8210  C CA  . ARG C 1 264 ? 71.696  -29.526 0.831   1.00 30.14  ? 264 ARG C CA  1 
ATOM   8211  C C   . ARG C 1 264 ? 70.231  -29.609 1.216   1.00 28.47  ? 264 ARG C C   1 
ATOM   8212  O O   . ARG C 1 264 ? 69.344  -29.454 0.374   1.00 28.15  ? 264 ARG C O   1 
ATOM   8213  C CB  . ARG C 1 264 ? 72.241  -28.115 1.124   1.00 27.10  ? 264 ARG C CB  1 
ATOM   8214  C CG  . ARG C 1 264 ? 71.235  -26.964 0.910   1.00 30.57  ? 264 ARG C CG  1 
ATOM   8215  C CD  . ARG C 1 264 ? 71.032  -26.652 -0.587  1.00 30.83  ? 264 ARG C CD  1 
ATOM   8216  N NE  . ARG C 1 264 ? 70.102  -25.554 -0.850  1.00 32.57  ? 264 ARG C NE  1 
ATOM   8217  C CZ  . ARG C 1 264 ? 68.777  -25.657 -0.839  1.00 32.12  ? 264 ARG C CZ  1 
ATOM   8218  N NH1 . ARG C 1 264 ? 68.172  -26.801 -0.566  1.00 25.96  ? 264 ARG C NH1 1 
ATOM   8219  N NH2 . ARG C 1 264 ? 68.041  -24.579 -1.102  1.00 29.22  ? 264 ARG C NH2 1 
ATOM   8220  N N   . ALA C 1 265 ? 69.995  -29.878 2.493   1.00 33.59  ? 265 ALA C N   1 
ATOM   8221  C CA  . ALA C 1 265 ? 68.698  -29.644 3.110   1.00 31.00  ? 265 ALA C CA  1 
ATOM   8222  C C   . ALA C 1 265 ? 68.770  -28.288 3.796   1.00 26.51  ? 265 ALA C C   1 
ATOM   8223  O O   . ALA C 1 265 ? 69.650  -28.058 4.633   1.00 28.57  ? 265 ALA C O   1 
ATOM   8224  C CB  . ALA C 1 265 ? 68.348  -30.745 4.105   1.00 22.53  ? 265 ALA C CB  1 
ATOM   8225  N N   . ARG C 1 266 ? 67.880  -27.383 3.431   1.00 23.91  ? 266 ARG C N   1 
ATOM   8226  C CA  . ARG C 1 266 ? 67.897  -26.045 4.011   1.00 21.71  ? 266 ARG C CA  1 
ATOM   8227  C C   . ARG C 1 266 ? 66.723  -25.917 4.974   1.00 21.45  ? 266 ARG C C   1 
ATOM   8228  O O   . ARG C 1 266 ? 65.570  -26.003 4.558   1.00 21.68  ? 266 ARG C O   1 
ATOM   8229  C CB  . ARG C 1 266 ? 67.849  -24.961 2.928   1.00 25.46  ? 266 ARG C CB  1 
ATOM   8230  C CG  . ARG C 1 266 ? 67.671  -23.536 3.510   1.00 33.04  ? 266 ARG C CG  1 
ATOM   8231  C CD  . ARG C 1 266 ? 68.044  -22.414 2.550   1.00 27.87  ? 266 ARG C CD  1 
ATOM   8232  N NE  . ARG C 1 266 ? 66.861  -21.717 2.042   1.00 46.00  ? 266 ARG C NE  1 
ATOM   8233  C CZ  . ARG C 1 266 ? 65.947  -21.066 2.768   1.00 47.75  ? 266 ARG C CZ  1 
ATOM   8234  N NH1 . ARG C 1 266 ? 66.017  -20.997 4.094   1.00 40.68  ? 266 ARG C NH1 1 
ATOM   8235  N NH2 . ARG C 1 266 ? 64.931  -20.466 2.146   1.00 35.43  ? 266 ARG C NH2 1 
ATOM   8236  N N   . PHE C 1 267 ? 67.025  -25.730 6.261   1.00 22.69  ? 267 PHE C N   1 
ATOM   8237  C CA  . PHE C 1 267 ? 66.001  -25.485 7.268   1.00 22.93  ? 267 PHE C CA  1 
ATOM   8238  C C   . PHE C 1 267 ? 65.231  -24.195 6.965   1.00 21.45  ? 267 PHE C C   1 
ATOM   8239  O O   . PHE C 1 267 ? 65.825  -23.133 6.751   1.00 22.86  ? 267 PHE C O   1 
ATOM   8240  C CB  . PHE C 1 267 ? 66.674  -25.402 8.633   1.00 18.97  ? 267 PHE C CB  1 
ATOM   8241  C CG  . PHE C 1 267 ? 65.765  -24.984 9.734   1.00 25.43  ? 267 PHE C CG  1 
ATOM   8242  C CD1 . PHE C 1 267 ? 65.539  -23.641 9.990   1.00 24.63  ? 267 PHE C CD1 1 
ATOM   8243  C CD2 . PHE C 1 267 ? 65.156  -25.936 10.546  1.00 23.70  ? 267 PHE C CD2 1 
ATOM   8244  C CE1 . PHE C 1 267 ? 64.701  -23.252 11.019  1.00 24.73  ? 267 PHE C CE1 1 
ATOM   8245  C CE2 . PHE C 1 267 ? 64.321  -25.553 11.563  1.00 24.89  ? 267 PHE C CE2 1 
ATOM   8246  C CZ  . PHE C 1 267 ? 64.102  -24.203 11.812  1.00 25.02  ? 267 PHE C CZ  1 
ATOM   8247  N N   . LEU C 1 268 ? 63.905  -24.277 6.954   1.00 20.30  ? 268 LEU C N   1 
ATOM   8248  C CA  . LEU C 1 268 ? 63.092  -23.110 6.611   1.00 21.38  ? 268 LEU C CA  1 
ATOM   8249  C C   . LEU C 1 268 ? 62.514  -22.417 7.837   1.00 21.38  ? 268 LEU C C   1 
ATOM   8250  O O   . LEU C 1 268 ? 62.665  -21.199 7.991   1.00 18.86  ? 268 LEU C O   1 
ATOM   8251  C CB  . LEU C 1 268 ? 61.968  -23.515 5.653   1.00 19.93  ? 268 LEU C CB  1 
ATOM   8252  C CG  . LEU C 1 268 ? 62.372  -24.211 4.348   1.00 22.01  ? 268 LEU C CG  1 
ATOM   8253  C CD1 . LEU C 1 268 ? 61.126  -24.621 3.567   1.00 22.95  ? 268 LEU C CD1 1 
ATOM   8254  C CD2 . LEU C 1 268 ? 63.267  -23.323 3.491   1.00 17.04  ? 268 LEU C CD2 1 
ATOM   8255  N N   . HIS C 1 269 ? 61.880  -23.173 8.730   1.00 19.99  ? 269 HIS C N   1 
ATOM   8256  C CA  . HIS C 1 269 ? 61.311  -22.604 9.943   1.00 21.30  ? 269 HIS C CA  1 
ATOM   8257  C C   . HIS C 1 269 ? 60.907  -23.732 10.873  1.00 21.16  ? 269 HIS C C   1 
ATOM   8258  O O   . HIS C 1 269 ? 60.789  -24.892 10.474  1.00 18.91  ? 269 HIS C O   1 
ATOM   8259  C CB  . HIS C 1 269 ? 60.075  -21.747 9.653   1.00 21.00  ? 269 HIS C CB  1 
ATOM   8260  C CG  . HIS C 1 269 ? 58.960  -22.540 9.066   1.00 18.29  ? 269 HIS C CG  1 
ATOM   8261  N ND1 . HIS C 1 269 ? 57.916  -23.025 9.815   1.00 21.39  ? 269 HIS C ND1 1 
ATOM   8262  C CD2 . HIS C 1 269 ? 58.774  -23.007 7.809   1.00 17.95  ? 269 HIS C CD2 1 
ATOM   8263  C CE1 . HIS C 1 269 ? 57.115  -23.738 9.041   1.00 21.76  ? 269 HIS C CE1 1 
ATOM   8264  N NE2 . HIS C 1 269 ? 57.618  -23.743 7.818   1.00 18.36  ? 269 HIS C NE2 1 
ATOM   8265  N N   . SER C 1 270 ? 60.648  -23.348 12.120  1.00 24.55  ? 270 SER C N   1 
ATOM   8266  C CA  . SER C 1 270 ? 59.914  -24.142 13.092  1.00 25.83  ? 270 SER C CA  1 
ATOM   8267  C C   . SER C 1 270 ? 58.600  -23.440 13.427  1.00 21.31  ? 270 SER C C   1 
ATOM   8268  O O   . SER C 1 270 ? 58.555  -22.215 13.550  1.00 27.01  ? 270 SER C O   1 
ATOM   8269  C CB  . SER C 1 270 ? 60.764  -24.358 14.368  1.00 27.42  ? 270 SER C CB  1 
ATOM   8270  O OG  . SER C 1 270 ? 60.879  -23.154 15.133  1.00 29.65  ? 270 SER C OG  1 
ATOM   8271  N N   . SER C 1 271 ? 57.530  -24.206 13.585  1.00 23.98  ? 271 SER C N   1 
ATOM   8272  C CA  . SER C 1 271 ? 56.242  -23.660 14.002  1.00 24.04  ? 271 SER C CA  1 
ATOM   8273  C C   . SER C 1 271 ? 55.646  -24.574 15.052  1.00 24.01  ? 271 SER C C   1 
ATOM   8274  O O   . SER C 1 271 ? 56.155  -25.665 15.309  1.00 28.28  ? 271 SER C O   1 
ATOM   8275  C CB  . SER C 1 271 ? 55.269  -23.527 12.826  1.00 23.87  ? 271 SER C CB  1 
ATOM   8276  O OG  . SER C 1 271 ? 55.851  -22.767 11.790  1.00 26.39  ? 271 SER C OG  1 
ATOM   8277  N N   . ILE C 1 272 ? 54.525  -24.156 15.633  1.00 25.67  ? 272 ILE C N   1 
ATOM   8278  C CA  . ILE C 1 272 ? 53.821  -24.967 16.616  1.00 24.45  ? 272 ILE C CA  1 
ATOM   8279  C C   . ILE C 1 272 ? 52.374  -25.139 16.186  1.00 31.53  ? 272 ILE C C   1 
ATOM   8280  O O   . ILE C 1 272 ? 51.682  -24.156 15.880  1.00 31.24  ? 272 ILE C O   1 
ATOM   8281  C CB  . ILE C 1 272 ? 53.882  -24.358 18.027  1.00 28.91  ? 272 ILE C CB  1 
ATOM   8282  C CG1 . ILE C 1 272 ? 55.327  -24.116 18.448  1.00 23.13  ? 272 ILE C CG1 1 
ATOM   8283  C CG2 . ILE C 1 272 ? 53.208  -25.293 19.015  1.00 32.27  ? 272 ILE C CG2 1 
ATOM   8284  C CD1 . ILE C 1 272 ? 55.480  -23.019 19.475  1.00 28.86  ? 272 ILE C CD1 1 
ATOM   8285  N N   . LEU C 1 273 ? 51.915  -26.385 16.185  1.00 32.62  ? 273 LEU C N   1 
ATOM   8286  C CA  . LEU C 1 273 ? 50.504  -26.671 15.988  1.00 36.74  ? 273 LEU C CA  1 
ATOM   8287  C C   . LEU C 1 273 ? 49.741  -26.285 17.248  1.00 38.00  ? 273 LEU C C   1 
ATOM   8288  O O   . LEU C 1 273 ? 50.196  -26.550 18.364  1.00 37.00  ? 273 LEU C O   1 
ATOM   8289  C CB  . LEU C 1 273 ? 50.306  -28.155 15.679  1.00 36.32  ? 273 LEU C CB  1 
ATOM   8290  C CG  . LEU C 1 273 ? 50.288  -28.617 14.221  1.00 42.21  ? 273 LEU C CG  1 
ATOM   8291  C CD1 . LEU C 1 273 ? 51.598  -28.330 13.560  1.00 37.94  ? 273 LEU C CD1 1 
ATOM   8292  C CD2 . LEU C 1 273 ? 50.000  -30.113 14.124  1.00 45.33  ? 273 LEU C CD2 1 
ATOM   8293  N N   . LYS C 1 274 ? 48.589  -25.639 17.067  1.00 37.04  ? 274 LYS C N   1 
ATOM   8294  C CA  . LYS C 1 274 ? 47.753  -25.184 18.174  1.00 42.82  ? 274 LYS C CA  1 
ATOM   8295  C C   . LYS C 1 274 ? 46.409  -25.893 18.139  1.00 45.69  ? 274 LYS C C   1 
ATOM   8296  O O   . LYS C 1 274 ? 45.766  -25.978 17.082  1.00 38.44  ? 274 LYS C O   1 
ATOM   8297  C CB  . LYS C 1 274 ? 47.531  -23.669 18.141  1.00 38.03  ? 274 LYS C CB  1 
ATOM   8298  C CG  . LYS C 1 274 ? 48.742  -22.897 17.681  1.00 39.09  ? 274 LYS C CG  1 
ATOM   8299  C CD  . LYS C 1 274 ? 49.800  -22.854 18.766  1.00 41.15  ? 274 LYS C CD  1 
ATOM   8300  C CE  . LYS C 1 274 ? 49.212  -22.627 20.151  1.00 40.37  ? 274 LYS C CE  1 
ATOM   8301  N NZ  . LYS C 1 274 ? 50.314  -22.288 21.103  1.00 49.18  ? 274 LYS C NZ  1 
ATOM   8302  N N   . TYR C 1 275 ? 45.983  -26.366 19.308  1.00 46.68  ? 275 TYR C N   1 
ATOM   8303  C CA  . TYR C 1 275 ? 44.767  -27.143 19.465  1.00 47.34  ? 275 TYR C CA  1 
ATOM   8304  C C   . TYR C 1 275 ? 43.838  -26.450 20.454  1.00 48.85  ? 275 TYR C C   1 
ATOM   8305  O O   . TYR C 1 275 ? 44.293  -25.745 21.360  1.00 49.22  ? 275 TYR C O   1 
ATOM   8306  C CB  . TYR C 1 275 ? 45.111  -28.561 19.919  1.00 48.79  ? 275 TYR C CB  1 
ATOM   8307  C CG  . TYR C 1 275 ? 45.872  -29.328 18.866  1.00 44.42  ? 275 TYR C CG  1 
ATOM   8308  C CD1 . TYR C 1 275 ? 45.196  -29.982 17.848  1.00 51.96  ? 275 TYR C CD1 1 
ATOM   8309  C CD2 . TYR C 1 275 ? 47.260  -29.376 18.866  1.00 44.17  ? 275 TYR C CD2 1 
ATOM   8310  C CE1 . TYR C 1 275 ? 45.872  -30.681 16.861  1.00 47.37  ? 275 TYR C CE1 1 
ATOM   8311  C CE2 . TYR C 1 275 ? 47.954  -30.087 17.875  1.00 50.42  ? 275 TYR C CE2 1 
ATOM   8312  C CZ  . TYR C 1 275 ? 47.241  -30.734 16.877  1.00 47.58  ? 275 TYR C CZ  1 
ATOM   8313  O OH  . TYR C 1 275 ? 47.866  -31.430 15.877  1.00 48.99  ? 275 TYR C OH  1 
ATOM   8314  N N   . GLU C 1 276 ? 42.532  -26.658 20.258  1.00 52.15  ? 276 GLU C N   1 
ATOM   8315  C CA  . GLU C 1 276 ? 41.453  -25.945 20.969  1.00 56.57  ? 276 GLU C CA  1 
ATOM   8316  C C   . GLU C 1 276 ? 41.725  -25.652 22.438  1.00 53.48  ? 276 GLU C C   1 
ATOM   8317  O O   . GLU C 1 276 ? 42.075  -26.549 23.200  1.00 61.03  ? 276 GLU C O   1 
ATOM   8318  C CB  . GLU C 1 276 ? 40.146  -26.740 20.869  1.00 58.65  ? 276 GLU C CB  1 
ATOM   8319  C CG  . GLU C 1 276 ? 39.438  -26.633 19.527  1.00 56.47  ? 276 GLU C CG  1 
ATOM   8320  C CD  . GLU C 1 276 ? 38.221  -25.728 19.583  1.00 70.83  ? 276 GLU C CD  1 
ATOM   8321  O OE1 . GLU C 1 276 ? 37.646  -25.425 18.512  1.00 67.48  ? 276 GLU C OE1 1 
ATOM   8322  O OE2 . GLU C 1 276 ? 37.840  -25.315 20.702  1.00 74.45  ? 276 GLU C OE2 1 
ATOM   8323  N N   . GLY C 1 284 ? 40.231  -35.072 26.574  1.00 57.35  ? 284 GLY C N   1 
ATOM   8324  C CA  . GLY C 1 284 ? 39.910  -35.765 25.336  1.00 62.31  ? 284 GLY C CA  1 
ATOM   8325  C C   . GLY C 1 284 ? 40.669  -35.317 24.093  1.00 58.62  ? 284 GLY C C   1 
ATOM   8326  O O   . GLY C 1 284 ? 41.899  -35.292 24.068  1.00 59.41  ? 284 GLY C O   1 
ATOM   8327  N N   . SER C 1 285 ? 39.928  -34.960 23.050  1.00 60.93  ? 285 SER C N   1 
ATOM   8328  C CA  . SER C 1 285 ? 40.494  -34.632 21.747  1.00 58.44  ? 285 SER C CA  1 
ATOM   8329  C C   . SER C 1 285 ? 40.261  -33.160 21.420  1.00 61.12  ? 285 SER C C   1 
ATOM   8330  O O   . SER C 1 285 ? 39.120  -32.683 21.452  1.00 64.55  ? 285 SER C O   1 
ATOM   8331  C CB  . SER C 1 285 ? 39.884  -35.528 20.667  1.00 56.87  ? 285 SER C CB  1 
ATOM   8332  O OG  . SER C 1 285 ? 39.360  -34.766 19.591  1.00 60.86  ? 285 SER C OG  1 
ATOM   8333  N N   . ALA C 1 286 ? 41.339  -32.448 21.096  1.00 62.63  ? 286 ALA C N   1 
ATOM   8334  C CA  . ALA C 1 286 ? 41.294  -31.024 20.789  1.00 59.04  ? 286 ALA C CA  1 
ATOM   8335  C C   . ALA C 1 286 ? 41.460  -30.805 19.292  1.00 56.21  ? 286 ALA C C   1 
ATOM   8336  O O   . ALA C 1 286 ? 42.314  -31.431 18.657  1.00 58.15  ? 286 ALA C O   1 
ATOM   8337  C CB  . ALA C 1 286 ? 42.384  -30.260 21.549  1.00 55.07  ? 286 ALA C CB  1 
ATOM   8338  N N   . LYS C 1 287 ? 40.642  -29.914 18.735  1.00 56.51  ? 287 LYS C N   1 
ATOM   8339  C CA  . LYS C 1 287 ? 40.635  -29.636 17.305  1.00 50.27  ? 287 LYS C CA  1 
ATOM   8340  C C   . LYS C 1 287 ? 41.697  -28.591 16.954  1.00 51.52  ? 287 LYS C C   1 
ATOM   8341  O O   . LYS C 1 287 ? 42.023  -27.713 17.758  1.00 50.19  ? 287 LYS C O   1 
ATOM   8342  C CB  . LYS C 1 287 ? 39.244  -29.170 16.873  1.00 49.44  ? 287 LYS C CB  1 
ATOM   8343  C CG  . LYS C 1 287 ? 39.091  -28.932 15.377  1.00 58.77  ? 287 LYS C CG  1 
ATOM   8344  C CD  . LYS C 1 287 ? 37.935  -29.743 14.800  1.00 55.74  ? 287 LYS C CD  1 
ATOM   8345  C CE  . LYS C 1 287 ? 37.512  -29.217 13.441  1.00 47.48  ? 287 LYS C CE  1 
ATOM   8346  N NZ  . LYS C 1 287 ? 36.693  -27.987 13.602  1.00 52.06  ? 287 LYS C NZ  1 
ATOM   8347  N N   . TRP C 1 288 ? 42.256  -28.710 15.749  1.00 50.67  ? 288 TRP C N   1 
ATOM   8348  C CA  . TRP C 1 288 ? 43.384  -27.875 15.331  1.00 42.87  ? 288 TRP C CA  1 
ATOM   8349  C C   . TRP C 1 288 ? 42.906  -26.460 15.015  1.00 43.44  ? 288 TRP C C   1 
ATOM   8350  O O   . TRP C 1 288 ? 42.159  -26.244 14.052  1.00 36.11  ? 288 TRP C O   1 
ATOM   8351  C CB  . TRP C 1 288 ? 44.073  -28.514 14.129  1.00 41.59  ? 288 TRP C CB  1 
ATOM   8352  C CG  . TRP C 1 288 ? 45.177  -27.681 13.502  1.00 41.83  ? 288 TRP C CG  1 
ATOM   8353  C CD1 . TRP C 1 288 ? 46.177  -26.994 14.156  1.00 37.51  ? 288 TRP C CD1 1 
ATOM   8354  C CD2 . TRP C 1 288 ? 45.409  -27.485 12.098  1.00 34.42  ? 288 TRP C CD2 1 
ATOM   8355  N NE1 . TRP C 1 288 ? 46.989  -26.366 13.239  1.00 39.41  ? 288 TRP C NE1 1 
ATOM   8356  C CE2 . TRP C 1 288 ? 46.547  -26.660 11.972  1.00 35.49  ? 288 TRP C CE2 1 
ATOM   8357  C CE3 . TRP C 1 288 ? 44.765  -27.931 10.936  1.00 33.20  ? 288 TRP C CE3 1 
ATOM   8358  C CZ2 . TRP C 1 288 ? 47.054  -26.274 10.735  1.00 34.15  ? 288 TRP C CZ2 1 
ATOM   8359  C CZ3 . TRP C 1 288 ? 45.269  -27.541 9.708   1.00 38.17  ? 288 TRP C CZ3 1 
ATOM   8360  C CH2 . TRP C 1 288 ? 46.403  -26.718 9.617   1.00 35.45  ? 288 TRP C CH2 1 
ATOM   8361  N N   . ILE C 1 289 ? 43.348  -25.486 15.810  1.00 45.03  ? 289 ILE C N   1 
ATOM   8362  C CA  . ILE C 1 289 ? 42.857  -24.128 15.622  1.00 40.70  ? 289 ILE C CA  1 
ATOM   8363  C C   . ILE C 1 289 ? 43.797  -23.278 14.768  1.00 38.34  ? 289 ILE C C   1 
ATOM   8364  O O   . ILE C 1 289 ? 43.335  -22.368 14.071  1.00 37.77  ? 289 ILE C O   1 
ATOM   8365  C CB  . ILE C 1 289 ? 42.586  -23.463 16.977  1.00 44.37  ? 289 ILE C CB  1 
ATOM   8366  C CG1 . ILE C 1 289 ? 43.675  -23.798 17.990  1.00 44.86  ? 289 ILE C CG1 1 
ATOM   8367  C CG2 . ILE C 1 289 ? 41.264  -23.963 17.515  1.00 47.76  ? 289 ILE C CG2 1 
ATOM   8368  C CD1 . ILE C 1 289 ? 43.402  -23.217 19.371  1.00 46.57  ? 289 ILE C CD1 1 
ATOM   8369  N N   . GLY C 1 290 ? 45.100  -23.556 14.791  1.00 37.69  ? 290 GLY C N   1 
ATOM   8370  C CA  . GLY C 1 290 ? 46.016  -22.848 13.903  1.00 36.20  ? 290 GLY C CA  1 
ATOM   8371  C C   . GLY C 1 290 ? 47.476  -23.154 14.195  1.00 33.85  ? 290 GLY C C   1 
ATOM   8372  O O   . GLY C 1 290 ? 47.809  -24.195 14.759  1.00 35.09  ? 290 GLY C O   1 
ATOM   8373  N N   . LEU C 1 291 ? 48.339  -22.219 13.802  1.00 38.69  ? 291 LEU C N   1 
ATOM   8374  C CA  . LEU C 1 291 ? 49.785  -22.367 13.916  1.00 33.82  ? 291 LEU C CA  1 
ATOM   8375  C C   . LEU C 1 291 ? 50.389  -21.100 14.510  1.00 36.49  ? 291 LEU C C   1 
ATOM   8376  O O   . LEU C 1 291 ? 49.998  -19.989 14.137  1.00 30.73  ? 291 LEU C O   1 
ATOM   8377  C CB  . LEU C 1 291 ? 50.407  -22.628 12.547  1.00 25.14  ? 291 LEU C CB  1 
ATOM   8378  C CG  . LEU C 1 291 ? 51.371  -23.781 12.339  1.00 35.31  ? 291 LEU C CG  1 
ATOM   8379  C CD1 . LEU C 1 291 ? 50.755  -25.058 12.822  1.00 30.05  ? 291 LEU C CD1 1 
ATOM   8380  C CD2 . LEU C 1 291 ? 51.698  -23.920 10.852  1.00 32.06  ? 291 LEU C CD2 1 
ATOM   8381  N N   . ASP C 1 292 ? 51.335  -21.279 15.436  1.00 29.22  ? 292 ASP C N   1 
ATOM   8382  C CA  . ASP C 1 292 ? 52.158  -20.211 15.980  1.00 31.01  ? 292 ASP C CA  1 
ATOM   8383  C C   . ASP C 1 292 ? 53.577  -20.413 15.489  1.00 32.20  ? 292 ASP C C   1 
ATOM   8384  O O   . ASP C 1 292 ? 54.027  -21.553 15.358  1.00 29.22  ? 292 ASP C O   1 
ATOM   8385  C CB  . ASP C 1 292 ? 52.176  -20.219 17.509  1.00 34.38  ? 292 ASP C CB  1 
ATOM   8386  C CG  . ASP C 1 292 ? 50.894  -19.716 18.111  1.00 37.98  ? 292 ASP C CG  1 
ATOM   8387  O OD1 . ASP C 1 292 ? 50.035  -19.242 17.345  1.00 35.36  ? 292 ASP C OD1 1 
ATOM   8388  O OD2 . ASP C 1 292 ? 50.749  -19.799 19.354  1.00 39.92  ? 292 ASP C OD2 1 
ATOM   8389  N N   . SER C 1 293 ? 54.291  -19.318 15.231  1.00 25.99  ? 293 SER C N   1 
ATOM   8390  C CA  . SER C 1 293 ? 55.650  -19.546 14.757  1.00 31.53  ? 293 SER C CA  1 
ATOM   8391  C C   . SER C 1 293 ? 56.667  -18.656 15.455  1.00 36.20  ? 293 SER C C   1 
ATOM   8392  O O   . SER C 1 293 ? 56.285  -17.761 16.217  1.00 39.68  ? 293 SER C O   1 
ATOM   8393  C CB  . SER C 1 293 ? 55.757  -19.361 13.252  1.00 28.88  ? 293 SER C CB  1 
ATOM   8394  O OG  . SER C 1 293 ? 56.965  -19.944 12.803  1.00 27.88  ? 293 SER C OG  1 
ATOM   8395  N N   . PRO C 1 294 ? 57.917  -18.718 15.047  1.00 30.64  ? 294 PRO C N   1 
ATOM   8396  C CA  . PRO C 1 294 ? 58.954  -19.246 15.926  1.00 32.24  ? 294 PRO C CA  1 
ATOM   8397  C C   . PRO C 1 294 ? 58.398  -20.311 16.859  1.00 31.58  ? 294 PRO C C   1 
ATOM   8398  O O   . PRO C 1 294 ? 57.611  -20.003 17.754  1.00 25.67  ? 294 PRO C O   1 
ATOM   8399  C CB  . PRO C 1 294 ? 59.421  -17.997 16.684  1.00 36.36  ? 294 PRO C CB  1 
ATOM   8400  C CG  . PRO C 1 294 ? 59.326  -16.930 15.669  1.00 32.41  ? 294 PRO C CG  1 
ATOM   8401  C CD  . PRO C 1 294 ? 58.277  -17.357 14.625  1.00 33.83  ? 294 PRO C CD  1 
ATOM   8402  N N   . SER C 1 295 ? 58.776  -21.571 16.681  1.00 33.51  ? 295 SER C N   1 
ATOM   8403  C CA  . SER C 1 295 ? 58.582  -22.482 17.795  1.00 29.32  ? 295 SER C CA  1 
ATOM   8404  C C   . SER C 1 295 ? 59.473  -22.047 18.950  1.00 26.72  ? 295 SER C C   1 
ATOM   8405  O O   . SER C 1 295 ? 60.256  -21.108 18.842  1.00 28.65  ? 295 SER C O   1 
ATOM   8406  C CB  . SER C 1 295 ? 58.898  -23.917 17.394  1.00 27.66  ? 295 SER C CB  1 
ATOM   8407  O OG  . SER C 1 295 ? 60.266  -24.206 17.633  1.00 27.89  ? 295 SER C OG  1 
ATOM   8408  N N   . ARG C 1 296 ? 59.367  -22.752 20.075  1.00 33.69  ? 296 ARG C N   1 
ATOM   8409  C CA  . ARG C 1 296 ? 60.277  -22.561 21.197  1.00 32.25  ? 296 ARG C CA  1 
ATOM   8410  C C   . ARG C 1 296 ? 61.260  -23.720 21.324  1.00 30.68  ? 296 ARG C C   1 
ATOM   8411  O O   . ARG C 1 296 ? 61.912  -23.873 22.363  1.00 36.29  ? 296 ARG C O   1 
ATOM   8412  C CB  . ARG C 1 296 ? 59.494  -22.382 22.502  1.00 36.69  ? 296 ARG C CB  1 
ATOM   8413  C CG  . ARG C 1 296 ? 58.874  -20.979 22.750  1.00 41.29  ? 296 ARG C CG  1 
ATOM   8414  C CD  . ARG C 1 296 ? 57.973  -20.515 21.596  1.00 44.44  ? 296 ARG C CD  1 
ATOM   8415  N NE  . ARG C 1 296 ? 57.229  -19.290 21.881  1.00 47.86  ? 296 ARG C NE  1 
ATOM   8416  C CZ  . ARG C 1 296 ? 57.439  -18.129 21.272  1.00 50.70  ? 296 ARG C CZ  1 
ATOM   8417  N NH1 . ARG C 1 296 ? 58.396  -17.985 20.365  1.00 47.90  ? 296 ARG C NH1 1 
ATOM   8418  N NH2 . ARG C 1 296 ? 56.670  -17.087 21.580  1.00 47.96  ? 296 ARG C NH2 1 
ATOM   8419  N N   . SER C 1 297 ? 61.372  -24.548 20.290  1.00 31.63  ? 297 SER C N   1 
ATOM   8420  C CA  . SER C 1 297 ? 62.114  -25.801 20.361  1.00 33.50  ? 297 SER C CA  1 
ATOM   8421  C C   . SER C 1 297 ? 63.304  -25.831 19.409  1.00 30.55  ? 297 SER C C   1 
ATOM   8422  O O   . SER C 1 297 ? 63.633  -26.878 18.853  1.00 32.59  ? 297 SER C O   1 
ATOM   8423  C CB  . SER C 1 297 ? 61.190  -26.974 20.071  1.00 31.15  ? 297 SER C CB  1 
ATOM   8424  O OG  . SER C 1 297 ? 60.003  -26.828 20.810  1.00 36.17  ? 297 SER C OG  1 
ATOM   8425  N N   . GLU C 1 298 ? 63.971  -24.706 19.221  1.00 29.59  ? 298 GLU C N   1 
ATOM   8426  C CA  . GLU C 1 298 ? 65.164  -24.653 18.380  1.00 31.11  ? 298 GLU C CA  1 
ATOM   8427  C C   . GLU C 1 298 ? 66.390  -24.648 19.284  1.00 36.64  ? 298 GLU C C   1 
ATOM   8428  O O   . GLU C 1 298 ? 66.859  -23.600 19.725  1.00 39.60  ? 298 GLU C O   1 
ATOM   8429  C CB  . GLU C 1 298 ? 65.146  -23.437 17.479  1.00 29.65  ? 298 GLU C CB  1 
ATOM   8430  C CG  . GLU C 1 298 ? 64.172  -23.514 16.340  1.00 29.83  ? 298 GLU C CG  1 
ATOM   8431  C CD  . GLU C 1 298 ? 64.281  -22.289 15.476  1.00 31.99  ? 298 GLU C CD  1 
ATOM   8432  O OE1 . GLU C 1 298 ? 65.334  -21.608 15.564  1.00 33.13  ? 298 GLU C OE1 1 
ATOM   8433  O OE2 . GLU C 1 298 ? 63.325  -21.985 14.728  1.00 32.38  ? 298 GLU C OE2 1 
ATOM   8434  N N   . PHE C 1 299 ? 66.908  -25.836 19.562  1.00 34.27  ? 299 PHE C N   1 
ATOM   8435  C CA  . PHE C 1 299 ? 68.200  -25.958 20.205  1.00 35.14  ? 299 PHE C CA  1 
ATOM   8436  C C   . PHE C 1 299 ? 68.892  -27.191 19.641  1.00 37.65  ? 299 PHE C C   1 
ATOM   8437  O O   . PHE C 1 299 ? 68.348  -27.891 18.780  1.00 37.04  ? 299 PHE C O   1 
ATOM   8438  C CB  . PHE C 1 299 ? 68.057  -26.000 21.729  1.00 41.23  ? 299 PHE C CB  1 
ATOM   8439  C CG  . PHE C 1 299 ? 66.829  -26.737 22.233  1.00 41.74  ? 299 PHE C CG  1 
ATOM   8440  C CD1 . PHE C 1 299 ? 65.594  -26.105 22.305  1.00 42.39  ? 299 PHE C CD1 1 
ATOM   8441  C CD2 . PHE C 1 299 ? 66.929  -28.042 22.703  1.00 37.49  ? 299 PHE C CD2 1 
ATOM   8442  C CE1 . PHE C 1 299 ? 64.471  -26.783 22.804  1.00 39.74  ? 299 PHE C CE1 1 
ATOM   8443  C CE2 . PHE C 1 299 ? 65.816  -28.711 23.202  1.00 39.13  ? 299 PHE C CE2 1 
ATOM   8444  C CZ  . PHE C 1 299 ? 64.587  -28.082 23.245  1.00 35.11  ? 299 PHE C CZ  1 
ATOM   8445  N N   . GLU C 1 300 ? 70.108  -27.455 20.124  1.00 40.20  ? 300 GLU C N   1 
ATOM   8446  C CA  . GLU C 1 300 ? 70.883  -28.548 19.549  1.00 33.31  ? 300 GLU C CA  1 
ATOM   8447  C C   . GLU C 1 300 ? 70.150  -29.872 19.699  1.00 36.90  ? 300 GLU C C   1 
ATOM   8448  O O   . GLU C 1 300 ? 70.179  -30.710 18.783  1.00 33.06  ? 300 GLU C O   1 
ATOM   8449  C CB  . GLU C 1 300 ? 72.272  -28.630 20.187  1.00 33.71  ? 300 GLU C CB  1 
ATOM   8450  C CG  . GLU C 1 300 ? 73.141  -29.703 19.540  1.00 42.64  ? 300 GLU C CG  1 
ATOM   8451  C CD  . GLU C 1 300 ? 74.606  -29.661 19.959  1.00 58.25  ? 300 GLU C CD  1 
ATOM   8452  O OE1 . GLU C 1 300 ? 75.391  -28.931 19.309  1.00 61.80  ? 300 GLU C OE1 1 
ATOM   8453  O OE2 . GLU C 1 300 ? 74.980  -30.377 20.920  1.00 60.18  ? 300 GLU C OE2 1 
ATOM   8454  N N   . ALA C 1 301 ? 69.461  -30.074 20.832  1.00 27.45  ? 301 ALA C N   1 
ATOM   8455  C CA  . ALA C 1 301 ? 68.922  -31.403 21.114  1.00 34.56  ? 301 ALA C CA  1 
ATOM   8456  C C   . ALA C 1 301 ? 67.737  -31.762 20.219  1.00 31.84  ? 301 ALA C C   1 
ATOM   8457  O O   . ALA C 1 301 ? 67.415  -32.944 20.083  1.00 26.87  ? 301 ALA C O   1 
ATOM   8458  C CB  . ALA C 1 301 ? 68.529  -31.520 22.585  1.00 32.86  ? 301 ALA C CB  1 
ATOM   8459  N N   . THR C 1 302 ? 67.066  -30.778 19.624  1.00 30.07  ? 302 THR C N   1 
ATOM   8460  C CA  . THR C 1 302 ? 66.102  -31.086 18.579  1.00 30.44  ? 302 THR C CA  1 
ATOM   8461  C C   . THR C 1 302 ? 66.683  -30.910 17.186  1.00 26.12  ? 302 THR C C   1 
ATOM   8462  O O   . THR C 1 302 ? 66.499  -31.785 16.341  1.00 24.32  ? 302 THR C O   1 
ATOM   8463  C CB  . THR C 1 302 ? 64.844  -30.214 18.706  1.00 25.70  ? 302 THR C CB  1 
ATOM   8464  O OG1 . THR C 1 302 ? 65.227  -28.840 18.812  1.00 28.06  ? 302 THR C OG1 1 
ATOM   8465  C CG2 . THR C 1 302 ? 64.022  -30.638 19.915  1.00 26.72  ? 302 THR C CG2 1 
ATOM   8466  N N   . LEU C 1 303 ? 67.395  -29.807 16.937  1.00 27.10  ? 303 LEU C N   1 
ATOM   8467  C CA  . LEU C 1 303 ? 67.819  -29.497 15.574  1.00 28.93  ? 303 LEU C CA  1 
ATOM   8468  C C   . LEU C 1 303 ? 68.832  -30.512 15.057  1.00 25.87  ? 303 LEU C C   1 
ATOM   8469  O O   . LEU C 1 303 ? 68.822  -30.846 13.869  1.00 22.06  ? 303 LEU C O   1 
ATOM   8470  C CB  . LEU C 1 303 ? 68.398  -28.082 15.493  1.00 27.10  ? 303 LEU C CB  1 
ATOM   8471  C CG  . LEU C 1 303 ? 67.494  -26.885 15.778  1.00 31.85  ? 303 LEU C CG  1 
ATOM   8472  C CD1 . LEU C 1 303 ? 68.342  -25.633 16.047  1.00 31.90  ? 303 LEU C CD1 1 
ATOM   8473  C CD2 . LEU C 1 303 ? 66.514  -26.652 14.627  1.00 29.05  ? 303 LEU C CD2 1 
ATOM   8474  N N   . LYS C 1 304 ? 69.707  -31.026 15.932  1.00 25.29  ? 304 LYS C N   1 
ATOM   8475  C CA  . LYS C 1 304 ? 70.754  -31.927 15.449  1.00 28.47  ? 304 LYS C CA  1 
ATOM   8476  C C   . LYS C 1 304 ? 70.201  -33.273 14.991  1.00 27.54  ? 304 LYS C C   1 
ATOM   8477  O O   . LYS C 1 304 ? 70.534  -33.697 13.870  1.00 25.04  ? 304 LYS C O   1 
ATOM   8478  C CB  . LYS C 1 304 ? 71.838  -32.097 16.517  1.00 31.31  ? 304 LYS C CB  1 
ATOM   8479  C CG  . LYS C 1 304 ? 72.950  -33.091 16.159  1.00 40.09  ? 304 LYS C CG  1 
ATOM   8480  C CD  . LYS C 1 304 ? 73.896  -33.253 17.359  1.00 45.28  ? 304 LYS C CD  1 
ATOM   8481  C CE  . LYS C 1 304 ? 74.098  -34.716 17.788  1.00 46.46  ? 304 LYS C CE  1 
ATOM   8482  N NZ  . LYS C 1 304 ? 75.428  -35.272 17.402  1.00 54.34  ? 304 LYS C NZ  1 
ATOM   8483  N N   . PRO C 1 305 ? 69.395  -34.003 15.778  1.00 25.70  ? 305 PRO C N   1 
ATOM   8484  C CA  . PRO C 1 305 ? 68.849  -35.261 15.246  1.00 24.04  ? 305 PRO C CA  1 
ATOM   8485  C C   . PRO C 1 305 ? 67.922  -35.047 14.058  1.00 24.67  ? 305 PRO C C   1 
ATOM   8486  O O   . PRO C 1 305 ? 67.870  -35.899 13.160  1.00 19.09  ? 305 PRO C O   1 
ATOM   8487  C CB  . PRO C 1 305 ? 68.108  -35.870 16.444  1.00 21.15  ? 305 PRO C CB  1 
ATOM   8488  C CG  . PRO C 1 305 ? 68.618  -35.125 17.646  1.00 27.37  ? 305 PRO C CG  1 
ATOM   8489  C CD  . PRO C 1 305 ? 68.893  -33.746 17.143  1.00 24.69  ? 305 PRO C CD  1 
ATOM   8490  N N   . ALA C 1 306 ? 67.208  -33.923 13.999  1.00 20.47  ? 306 ALA C N   1 
ATOM   8491  C CA  . ALA C 1 306 ? 66.316  -33.720 12.862  1.00 24.13  ? 306 ALA C CA  1 
ATOM   8492  C C   . ALA C 1 306 ? 67.122  -33.539 11.587  1.00 24.86  ? 306 ALA C C   1 
ATOM   8493  O O   . ALA C 1 306 ? 66.851  -34.192 10.573  1.00 23.71  ? 306 ALA C O   1 
ATOM   8494  C CB  . ALA C 1 306 ? 65.403  -32.518 13.096  1.00 21.11  ? 306 ALA C CB  1 
ATOM   8495  N N   . GLU C 1 307 ? 68.136  -32.669 11.631  1.00 24.89  ? 307 GLU C N   1 
ATOM   8496  C CA  . GLU C 1 307 ? 69.003  -32.479 10.471  1.00 24.93  ? 307 GLU C CA  1 
ATOM   8497  C C   . GLU C 1 307 ? 69.569  -33.809 9.996   1.00 25.79  ? 307 GLU C C   1 
ATOM   8498  O O   . GLU C 1 307 ? 69.553  -34.103 8.795   1.00 26.59  ? 307 GLU C O   1 
ATOM   8499  C CB  . GLU C 1 307 ? 70.148  -31.513 10.787  1.00 28.43  ? 307 GLU C CB  1 
ATOM   8500  C CG  . GLU C 1 307 ? 71.271  -31.569 9.736   1.00 35.08  ? 307 GLU C CG  1 
ATOM   8501  C CD  . GLU C 1 307 ? 72.540  -30.810 10.125  1.00 42.18  ? 307 GLU C CD  1 
ATOM   8502  O OE1 . GLU C 1 307 ? 72.569  -30.146 11.185  1.00 42.99  ? 307 GLU C OE1 1 
ATOM   8503  O OE2 . GLU C 1 307 ? 73.520  -30.874 9.350   1.00 49.91  ? 307 GLU C OE2 1 
ATOM   8504  N N   . GLU C 1 308 ? 70.063  -34.638 10.928  1.00 24.43  ? 308 GLU C N   1 
ATOM   8505  C CA  . GLU C 1 308 ? 70.640  -35.922 10.526  1.00 28.94  ? 308 GLU C CA  1 
ATOM   8506  C C   . GLU C 1 308 ? 69.584  -36.827 9.893   1.00 23.03  ? 308 GLU C C   1 
ATOM   8507  O O   . GLU C 1 308 ? 69.828  -37.460 8.860   1.00 25.72  ? 308 GLU C O   1 
ATOM   8508  C CB  . GLU C 1 308 ? 71.301  -36.622 11.716  1.00 29.77  ? 308 GLU C CB  1 
ATOM   8509  C CG  . GLU C 1 308 ? 71.867  -37.999 11.324  1.00 37.24  ? 308 GLU C CG  1 
ATOM   8510  C CD  . GLU C 1 308 ? 72.568  -38.722 12.475  1.00 54.17  ? 308 GLU C CD  1 
ATOM   8511  O OE1 . GLU C 1 308 ? 73.591  -38.183 12.962  1.00 62.69  ? 308 GLU C OE1 1 
ATOM   8512  O OE2 . GLU C 1 308 ? 72.120  -39.835 12.863  1.00 42.00  ? 308 GLU C OE2 1 
ATOM   8513  N N   . PHE C 1 309 ? 68.388  -36.867 10.463  1.00 23.19  ? 309 PHE C N   1 
ATOM   8514  C CA  . PHE C 1 309 ? 67.346  -37.641 9.809   1.00 23.67  ? 309 PHE C CA  1 
ATOM   8515  C C   . PHE C 1 309 ? 66.962  -37.007 8.475   1.00 23.75  ? 309 PHE C C   1 
ATOM   8516  O O   . PHE C 1 309 ? 66.692  -37.716 7.501   1.00 23.86  ? 309 PHE C O   1 
ATOM   8517  C CB  . PHE C 1 309 ? 66.124  -37.796 10.717  1.00 19.44  ? 309 PHE C CB  1 
ATOM   8518  C CG  . PHE C 1 309 ? 65.082  -38.697 10.133  1.00 23.82  ? 309 PHE C CG  1 
ATOM   8519  C CD1 . PHE C 1 309 ? 64.112  -38.197 9.277   1.00 20.91  ? 309 PHE C CD1 1 
ATOM   8520  C CD2 . PHE C 1 309 ? 65.117  -40.057 10.375  1.00 21.35  ? 309 PHE C CD2 1 
ATOM   8521  C CE1 . PHE C 1 309 ? 63.180  -39.034 8.696   1.00 22.93  ? 309 PHE C CE1 1 
ATOM   8522  C CE2 . PHE C 1 309 ? 64.175  -40.908 9.802   1.00 23.35  ? 309 PHE C CE2 1 
ATOM   8523  C CZ  . PHE C 1 309 ? 63.213  -40.396 8.955   1.00 24.01  ? 309 PHE C CZ  1 
ATOM   8524  N N   . ILE C 1 310 ? 66.971  -35.678 8.387   1.00 23.50  ? 310 ILE C N   1 
ATOM   8525  C CA  . ILE C 1 310 ? 66.573  -35.065 7.121   1.00 27.80  ? 310 ILE C CA  1 
ATOM   8526  C C   . ILE C 1 310 ? 67.643  -35.282 6.049   1.00 26.16  ? 310 ILE C C   1 
ATOM   8527  O O   . ILE C 1 310 ? 67.321  -35.553 4.890   1.00 21.95  ? 310 ILE C O   1 
ATOM   8528  C CB  . ILE C 1 310 ? 66.252  -33.571 7.286   1.00 23.53  ? 310 ILE C CB  1 
ATOM   8529  C CG1 . ILE C 1 310 ? 64.992  -33.347 8.152   1.00 26.04  ? 310 ILE C CG1 1 
ATOM   8530  C CG2 . ILE C 1 310 ? 66.110  -32.917 5.910   1.00 25.04  ? 310 ILE C CG2 1 
ATOM   8531  C CD1 . ILE C 1 310 ? 63.719  -33.973 7.635   1.00 21.86  ? 310 ILE C CD1 1 
ATOM   8532  N N   . GLU C 1 311 ? 68.928  -35.141 6.397   1.00 26.32  ? 311 GLU C N   1 
ATOM   8533  C CA  . GLU C 1 311 ? 69.964  -35.360 5.380   1.00 28.34  ? 311 GLU C CA  1 
ATOM   8534  C C   . GLU C 1 311 ? 69.855  -36.762 4.776   1.00 30.08  ? 311 GLU C C   1 
ATOM   8535  O O   . GLU C 1 311 ? 70.114  -36.947 3.579   1.00 36.07  ? 311 GLU C O   1 
ATOM   8536  C CB  . GLU C 1 311 ? 71.357  -35.142 5.975   1.00 27.69  ? 311 GLU C CB  1 
ATOM   8537  C CG  . GLU C 1 311 ? 72.554  -35.372 4.996   1.00 34.39  ? 311 GLU C CG  1 
ATOM   8538  C CD  . GLU C 1 311 ? 72.292  -34.847 3.583   1.00 38.03  ? 311 GLU C CD  1 
ATOM   8539  O OE1 . GLU C 1 311 ? 71.924  -33.654 3.463   1.00 30.65  ? 311 GLU C OE1 1 
ATOM   8540  O OE2 . GLU C 1 311 ? 72.462  -35.630 2.604   1.00 36.51  ? 311 GLU C OE2 1 
ATOM   8541  N N   . MET C 1 312 ? 69.461  -37.740 5.611   1.00 28.96  ? 312 MET C N   1 
ATOM   8542  C CA  . MET C 1 312 ? 69.231  -39.130 5.221   1.00 26.71  ? 312 MET C CA  1 
ATOM   8543  C C   . MET C 1 312 ? 68.104  -39.249 4.194   1.00 29.17  ? 312 MET C C   1 
ATOM   8544  O O   . MET C 1 312 ? 68.280  -39.878 3.144   1.00 28.56  ? 312 MET C O   1 
ATOM   8545  C CB  . MET C 1 312 ? 68.899  -39.963 6.469   1.00 28.10  ? 312 MET C CB  1 
ATOM   8546  C CG  . MET C 1 312 ? 69.229  -41.465 6.324   1.00 37.86  ? 312 MET C CG  1 
ATOM   8547  S SD  . MET C 1 312 ? 67.699  -42.314 6.062   1.00 51.74  ? 312 MET C SD  1 
ATOM   8548  C CE  . MET C 1 312 ? 67.058  -42.250 7.741   1.00 30.12  ? 312 MET C CE  1 
ATOM   8549  N N   . ILE C 1 313 ? 66.951  -38.614 4.446   1.00 25.49  ? 313 ILE C N   1 
ATOM   8550  C CA  . ILE C 1 313 ? 65.892  -38.691 3.441   1.00 29.58  ? 313 ILE C CA  1 
ATOM   8551  C C   . ILE C 1 313 ? 66.367  -38.046 2.139   1.00 26.39  ? 313 ILE C C   1 
ATOM   8552  O O   . ILE C 1 313 ? 66.063  -38.535 1.042   1.00 22.63  ? 313 ILE C O   1 
ATOM   8553  C CB  . ILE C 1 313 ? 64.556  -38.095 3.953   1.00 30.57  ? 313 ILE C CB  1 
ATOM   8554  C CG1 . ILE C 1 313 ? 64.785  -36.931 4.892   1.00 32.09  ? 313 ILE C CG1 1 
ATOM   8555  C CG2 . ILE C 1 313 ? 63.748  -39.147 4.752   1.00 29.13  ? 313 ILE C CG2 1 
ATOM   8556  C CD1 . ILE C 1 313 ? 63.920  -35.690 4.636   1.00 29.81  ? 313 ILE C CD1 1 
ATOM   8557  N N   . ARG C 1 314 ? 67.189  -36.997 2.236   1.00 24.60  ? 314 ARG C N   1 
ATOM   8558  C CA  . ARG C 1 314 ? 67.751  -36.391 1.026   1.00 30.15  ? 314 ARG C CA  1 
ATOM   8559  C C   . ARG C 1 314 ? 68.681  -37.357 0.301   1.00 26.91  ? 314 ARG C C   1 
ATOM   8560  O O   . ARG C 1 314 ? 68.647  -37.460 -0.931  1.00 29.82  ? 314 ARG C O   1 
ATOM   8561  C CB  . ARG C 1 314 ? 68.504  -35.097 1.358   1.00 25.92  ? 314 ARG C CB  1 
ATOM   8562  C CG  . ARG C 1 314 ? 68.666  -34.138 0.163   1.00 23.69  ? 314 ARG C CG  1 
ATOM   8563  C CD  . ARG C 1 314 ? 69.326  -32.808 0.549   1.00 26.28  ? 314 ARG C CD  1 
ATOM   8564  N NE  . ARG C 1 314 ? 70.706  -33.012 0.965   1.00 28.94  ? 314 ARG C NE  1 
ATOM   8565  C CZ  . ARG C 1 314 ? 71.716  -33.212 0.124   1.00 32.30  ? 314 ARG C CZ  1 
ATOM   8566  N NH1 . ARG C 1 314 ? 71.558  -33.113 -1.189  1.00 31.54  ? 314 ARG C NH1 1 
ATOM   8567  N NH2 . ARG C 1 314 ? 72.914  -33.521 0.609   1.00 27.91  ? 314 ARG C NH2 1 
ATOM   8568  N N   . THR C 1 315 ? 69.543  -38.041 1.049   1.00 28.93  ? 315 THR C N   1 
ATOM   8569  C CA  . THR C 1 315 ? 70.429  -39.044 0.464   1.00 30.81  ? 315 THR C CA  1 
ATOM   8570  C C   . THR C 1 315 ? 69.654  -40.124 -0.299  1.00 28.90  ? 315 THR C C   1 
ATOM   8571  O O   . THR C 1 315 ? 70.094  -40.590 -1.358  1.00 30.73  ? 315 THR C O   1 
ATOM   8572  C CB  . THR C 1 315 ? 71.275  -39.649 1.577   1.00 26.56  ? 315 THR C CB  1 
ATOM   8573  O OG1 . THR C 1 315 ? 72.152  -38.632 2.062   1.00 36.71  ? 315 THR C OG1 1 
ATOM   8574  C CG2 . THR C 1 315 ? 72.092  -40.848 1.072   1.00 28.18  ? 315 THR C CG2 1 
ATOM   8575  N N   . ILE C 1 316 ? 68.494  -40.536 0.206   1.00 29.04  ? 316 ILE C N   1 
ATOM   8576  C CA  . ILE C 1 316 ? 67.768  -41.562 -0.534  1.00 30.13  ? 316 ILE C CA  1 
ATOM   8577  C C   . ILE C 1 316 ? 67.054  -40.977 -1.734  1.00 28.94  ? 316 ILE C C   1 
ATOM   8578  O O   . ILE C 1 316 ? 66.608  -41.730 -2.604  1.00 33.61  ? 316 ILE C O   1 
ATOM   8579  C CB  . ILE C 1 316 ? 66.792  -42.360 0.351   1.00 30.54  ? 316 ILE C CB  1 
ATOM   8580  C CG1 . ILE C 1 316 ? 65.840  -41.498 1.122   1.00 36.64  ? 316 ILE C CG1 1 
ATOM   8581  C CG2 . ILE C 1 316 ? 67.541  -43.112 1.440   1.00 35.13  ? 316 ILE C CG2 1 
ATOM   8582  C CD1 . ILE C 1 316 ? 64.866  -42.367 1.963   1.00 32.41  ? 316 ILE C CD1 1 
ATOM   8583  N N   . GLY C 1 317 ? 66.978  -39.661 -1.843  1.00 24.73  ? 317 GLY C N   1 
ATOM   8584  C CA  . GLY C 1 317 ? 66.610  -39.056 -3.109  1.00 28.72  ? 317 GLY C CA  1 
ATOM   8585  C C   . GLY C 1 317 ? 65.386  -38.160 -3.087  1.00 29.09  ? 317 GLY C C   1 
ATOM   8586  O O   . GLY C 1 317 ? 65.016  -37.632 -4.145  1.00 21.88  ? 317 GLY C O   1 
ATOM   8587  N N   . TYR C 1 318 ? 64.724  -37.950 -1.959  1.00 23.94  ? 318 TYR C N   1 
ATOM   8588  C CA  . TYR C 1 318 ? 63.616  -37.010 -1.949  1.00 27.20  ? 318 TYR C CA  1 
ATOM   8589  C C   . TYR C 1 318 ? 64.097  -35.592 -2.226  1.00 24.28  ? 318 TYR C C   1 
ATOM   8590  O O   . TYR C 1 318 ? 65.069  -35.123 -1.628  1.00 28.96  ? 318 TYR C O   1 
ATOM   8591  C CB  . TYR C 1 318 ? 62.889  -37.040 -0.615  1.00 24.85  ? 318 TYR C CB  1 
ATOM   8592  C CG  . TYR C 1 318 ? 61.745  -36.082 -0.645  1.00 25.98  ? 318 TYR C CG  1 
ATOM   8593  C CD1 . TYR C 1 318 ? 60.700  -36.252 -1.548  1.00 24.69  ? 318 TYR C CD1 1 
ATOM   8594  C CD2 . TYR C 1 318 ? 61.727  -34.970 0.177   1.00 25.29  ? 318 TYR C CD2 1 
ATOM   8595  C CE1 . TYR C 1 318 ? 59.626  -35.355 -1.594  1.00 24.81  ? 318 TYR C CE1 1 
ATOM   8596  C CE2 . TYR C 1 318 ? 60.667  -34.070 0.139   1.00 28.54  ? 318 TYR C CE2 1 
ATOM   8597  C CZ  . TYR C 1 318 ? 59.619  -34.271 -0.750  1.00 29.56  ? 318 TYR C CZ  1 
ATOM   8598  O OH  . TYR C 1 318 ? 58.579  -33.367 -0.787  1.00 29.07  ? 318 TYR C OH  1 
ATOM   8599  N N   . ARG C 1 319 ? 63.411  -34.907 -3.127  1.00 25.42  ? 319 ARG C N   1 
ATOM   8600  C CA  . ARG C 1 319 ? 63.669  -33.503 -3.396  1.00 25.89  ? 319 ARG C CA  1 
ATOM   8601  C C   . ARG C 1 319 ? 62.348  -32.744 -3.297  1.00 23.93  ? 319 ARG C C   1 
ATOM   8602  O O   . ARG C 1 319 ? 61.312  -33.250 -3.720  1.00 25.64  ? 319 ARG C O   1 
ATOM   8603  C CB  . ARG C 1 319 ? 64.329  -33.324 -4.777  1.00 29.26  ? 319 ARG C CB  1 
ATOM   8604  C CG  . ARG C 1 319 ? 65.514  -34.275 -5.037  1.00 26.72  ? 319 ARG C CG  1 
ATOM   8605  C CD  . ARG C 1 319 ? 66.794  -33.713 -4.415  1.00 31.10  ? 319 ARG C CD  1 
ATOM   8606  N NE  . ARG C 1 319 ? 67.993  -34.488 -4.735  1.00 25.09  ? 319 ARG C NE  1 
ATOM   8607  C CZ  . ARG C 1 319 ? 68.523  -35.411 -3.944  1.00 27.74  ? 319 ARG C CZ  1 
ATOM   8608  N NH1 . ARG C 1 319 ? 67.957  -35.743 -2.788  1.00 25.01  ? 319 ARG C NH1 1 
ATOM   8609  N NH2 . ARG C 1 319 ? 69.639  -36.032 -4.329  1.00 24.69  ? 319 ARG C NH2 1 
ATOM   8610  N N   . GLY C 1 320 ? 62.383  -31.536 -2.732  1.00 21.89  ? 320 GLY C N   1 
ATOM   8611  C CA  . GLY C 1 320 ? 61.175  -30.784 -2.459  1.00 19.21  ? 320 GLY C CA  1 
ATOM   8612  C C   . GLY C 1 320 ? 61.037  -30.477 -0.979  1.00 21.58  ? 320 GLY C C   1 
ATOM   8613  O O   . GLY C 1 320 ? 62.004  -30.597 -0.230  1.00 19.80  ? 320 GLY C O   1 
ATOM   8614  N N   . TYR C 1 321 ? 59.835  -30.131 -0.535  1.00 22.28  ? 321 TYR C N   1 
ATOM   8615  C CA  . TYR C 1 321 ? 59.592  -29.764 0.854   1.00 21.92  ? 321 TYR C CA  1 
ATOM   8616  C C   . TYR C 1 321 ? 59.275  -30.996 1.697   1.00 20.24  ? 321 TYR C C   1 
ATOM   8617  O O   . TYR C 1 321 ? 58.656  -31.945 1.222   1.00 21.72  ? 321 TYR C O   1 
ATOM   8618  C CB  . TYR C 1 321 ? 58.453  -28.741 0.923   1.00 19.67  ? 321 TYR C CB  1 
ATOM   8619  C CG  . TYR C 1 321 ? 58.847  -27.495 0.183   1.00 22.88  ? 321 TYR C CG  1 
ATOM   8620  C CD1 . TYR C 1 321 ? 59.570  -26.490 0.816   1.00 18.44  ? 321 TYR C CD1 1 
ATOM   8621  C CD2 . TYR C 1 321 ? 58.565  -27.349 -1.173  1.00 21.34  ? 321 TYR C CD2 1 
ATOM   8622  C CE1 . TYR C 1 321 ? 59.972  -25.366 0.135   1.00 21.96  ? 321 TYR C CE1 1 
ATOM   8623  C CE2 . TYR C 1 321 ? 58.966  -26.211 -1.863  1.00 20.05  ? 321 TYR C CE2 1 
ATOM   8624  C CZ  . TYR C 1 321 ? 59.666  -25.232 -1.203  1.00 21.58  ? 321 TYR C CZ  1 
ATOM   8625  O OH  . TYR C 1 321 ? 60.069  -24.100 -1.877  1.00 25.45  ? 321 TYR C OH  1 
ATOM   8626  N N   . VAL C 1 322 ? 59.713  -30.967 2.951   1.00 17.80  ? 322 VAL C N   1 
ATOM   8627  C CA  . VAL C 1 322 ? 59.527  -32.058 3.902   1.00 20.56  ? 322 VAL C CA  1 
ATOM   8628  C C   . VAL C 1 322 ? 59.562  -31.459 5.301   1.00 21.16  ? 322 VAL C C   1 
ATOM   8629  O O   . VAL C 1 322 ? 60.257  -30.468 5.549   1.00 20.01  ? 322 VAL C O   1 
ATOM   8630  C CB  . VAL C 1 322 ? 60.610  -33.149 3.724   1.00 25.92  ? 322 VAL C CB  1 
ATOM   8631  C CG1 . VAL C 1 322 ? 61.994  -32.553 3.960   1.00 22.98  ? 322 VAL C CG1 1 
ATOM   8632  C CG2 . VAL C 1 322 ? 60.381  -34.342 4.654   1.00 22.05  ? 322 VAL C CG2 1 
ATOM   8633  N N   . ASN C 1 323 ? 58.768  -32.020 6.204   1.00 23.15  ? 323 ASN C N   1 
ATOM   8634  C CA  . ASN C 1 323 ? 58.739  -31.535 7.576   1.00 22.11  ? 323 ASN C CA  1 
ATOM   8635  C C   . ASN C 1 323 ? 58.715  -32.727 8.522   1.00 23.79  ? 323 ASN C C   1 
ATOM   8636  O O   . ASN C 1 323 ? 58.282  -33.816 8.151   1.00 24.34  ? 323 ASN C O   1 
ATOM   8637  C CB  . ASN C 1 323 ? 57.544  -30.598 7.831   1.00 22.77  ? 323 ASN C CB  1 
ATOM   8638  C CG  . ASN C 1 323 ? 56.209  -31.252 7.549   1.00 27.92  ? 323 ASN C CG  1 
ATOM   8639  O OD1 . ASN C 1 323 ? 55.691  -31.213 6.419   1.00 30.64  ? 323 ASN C OD1 1 
ATOM   8640  N ND2 . ASN C 1 323 ? 55.644  -31.855 8.565   1.00 26.87  ? 323 ASN C ND2 1 
ATOM   8641  N N   . ILE C 1 324 ? 59.224  -32.518 9.735   1.00 24.54  ? 324 ILE C N   1 
ATOM   8642  C CA  . ILE C 1 324 ? 59.338  -33.561 10.748  1.00 24.45  ? 324 ILE C CA  1 
ATOM   8643  C C   . ILE C 1 324 ? 58.796  -33.016 12.066  1.00 23.32  ? 324 ILE C C   1 
ATOM   8644  O O   . ILE C 1 324 ? 59.227  -31.953 12.519  1.00 23.10  ? 324 ILE C O   1 
ATOM   8645  C CB  . ILE C 1 324 ? 60.798  -34.047 10.906  1.00 24.17  ? 324 ILE C CB  1 
ATOM   8646  C CG1 . ILE C 1 324 ? 60.907  -35.192 11.903  1.00 22.06  ? 324 ILE C CG1 1 
ATOM   8647  C CG2 . ILE C 1 324 ? 61.750  -32.918 11.312  1.00 24.18  ? 324 ILE C CG2 1 
ATOM   8648  C CD1 . ILE C 1 324 ? 62.245  -35.960 11.784  1.00 23.06  ? 324 ILE C CD1 1 
ATOM   8649  N N   . ASP C 1 325 ? 57.850  -33.741 12.663  1.00 21.02  ? 325 ASP C N   1 
ATOM   8650  C CA  . ASP C 1 325 ? 57.165  -33.374 13.897  1.00 27.59  ? 325 ASP C CA  1 
ATOM   8651  C C   . ASP C 1 325 ? 57.890  -33.948 15.100  1.00 30.17  ? 325 ASP C C   1 
ATOM   8652  O O   . ASP C 1 325 ? 58.384  -35.082 15.062  1.00 28.16  ? 325 ASP C O   1 
ATOM   8653  C CB  . ASP C 1 325 ? 55.743  -33.946 13.935  1.00 28.65  ? 325 ASP C CB  1 
ATOM   8654  C CG  . ASP C 1 325 ? 54.854  -33.364 12.896  1.00 44.52  ? 325 ASP C CG  1 
ATOM   8655  O OD1 . ASP C 1 325 ? 54.005  -32.503 13.246  1.00 51.74  ? 325 ASP C OD1 1 
ATOM   8656  O OD2 . ASP C 1 325 ? 54.989  -33.785 11.726  1.00 46.47  ? 325 ASP C OD2 1 
ATOM   8657  N N   . GLY C 1 326 ? 57.850  -33.212 16.209  1.00 26.40  ? 326 GLY C N   1 
ATOM   8658  C CA  . GLY C 1 326 ? 58.408  -33.762 17.429  1.00 29.79  ? 326 GLY C CA  1 
ATOM   8659  C C   . GLY C 1 326 ? 57.756  -33.173 18.660  1.00 31.19  ? 326 GLY C C   1 
ATOM   8660  O O   . GLY C 1 326 ? 56.866  -32.326 18.571  1.00 31.11  ? 326 GLY C O   1 
ATOM   8661  N N   . ILE C 1 327 ? 58.227  -33.621 19.824  1.00 27.59  ? 327 ILE C N   1 
ATOM   8662  C CA  . ILE C 1 327 ? 57.850  -33.037 21.104  1.00 31.26  ? 327 ILE C CA  1 
ATOM   8663  C C   . ILE C 1 327 ? 59.090  -32.955 21.984  1.00 32.01  ? 327 ILE C C   1 
ATOM   8664  O O   . ILE C 1 327 ? 60.111  -33.584 21.711  1.00 33.48  ? 327 ILE C O   1 
ATOM   8665  C CB  . ILE C 1 327 ? 56.754  -33.855 21.815  1.00 34.81  ? 327 ILE C CB  1 
ATOM   8666  C CG1 . ILE C 1 327 ? 57.306  -35.251 22.163  1.00 32.42  ? 327 ILE C CG1 1 
ATOM   8667  C CG2 . ILE C 1 327 ? 55.483  -33.907 20.954  1.00 29.26  ? 327 ILE C CG2 1 
ATOM   8668  C CD1 . ILE C 1 327 ? 56.257  -36.284 22.559  1.00 33.87  ? 327 ILE C CD1 1 
ATOM   8669  N N   . VAL C 1 328 ? 58.976  -32.176 23.061  1.00 30.08  ? 328 VAL C N   1 
ATOM   8670  C CA  . VAL C 1 328 ? 59.948  -32.129 24.150  1.00 33.93  ? 328 VAL C CA  1 
ATOM   8671  C C   . VAL C 1 328 ? 59.199  -32.362 25.453  1.00 36.23  ? 328 VAL C C   1 
ATOM   8672  O O   . VAL C 1 328 ? 58.173  -31.723 25.695  1.00 34.43  ? 328 VAL C O   1 
ATOM   8673  C CB  . VAL C 1 328 ? 60.683  -30.778 24.216  1.00 38.33  ? 328 VAL C CB  1 
ATOM   8674  C CG1 . VAL C 1 328 ? 61.701  -30.793 25.357  1.00 35.02  ? 328 VAL C CG1 1 
ATOM   8675  C CG2 . VAL C 1 328 ? 61.342  -30.454 22.870  1.00 35.20  ? 328 VAL C CG2 1 
ATOM   8676  N N   . LEU C 1 329 ? 59.703  -33.263 26.295  1.00 40.63  ? 329 LEU C N   1 
ATOM   8677  C CA  . LEU C 1 329 ? 59.027  -33.509 27.564  1.00 42.01  ? 329 LEU C CA  1 
ATOM   8678  C C   . LEU C 1 329 ? 59.544  -32.572 28.668  1.00 43.07  ? 329 LEU C C   1 
ATOM   8679  O O   . LEU C 1 329 ? 60.485  -31.794 28.477  1.00 37.51  ? 329 LEU C O   1 
ATOM   8680  C CB  . LEU C 1 329 ? 59.185  -34.972 27.979  1.00 40.15  ? 329 LEU C CB  1 
ATOM   8681  C CG  . LEU C 1 329 ? 58.818  -36.072 26.970  1.00 42.08  ? 329 LEU C CG  1 
ATOM   8682  C CD1 . LEU C 1 329 ? 58.842  -37.436 27.662  1.00 40.48  ? 329 LEU C CD1 1 
ATOM   8683  C CD2 . LEU C 1 329 ? 57.473  -35.837 26.319  1.00 34.19  ? 329 LEU C CD2 1 
ATOM   8684  N N   . ASP C 1 330 ? 58.901  -32.655 29.844  1.00 47.20  ? 330 ASP C N   1 
ATOM   8685  C CA  . ASP C 1 330 ? 59.358  -31.891 31.006  1.00 43.20  ? 330 ASP C CA  1 
ATOM   8686  C C   . ASP C 1 330 ? 60.779  -32.264 31.380  1.00 39.28  ? 330 ASP C C   1 
ATOM   8687  O O   . ASP C 1 330 ? 61.608  -31.392 31.665  1.00 42.45  ? 330 ASP C O   1 
ATOM   8688  C CB  . ASP C 1 330 ? 58.440  -32.128 32.204  1.00 48.44  ? 330 ASP C CB  1 
ATOM   8689  C CG  . ASP C 1 330 ? 56.979  -31.957 31.863  1.00 55.29  ? 330 ASP C CG  1 
ATOM   8690  O OD1 . ASP C 1 330 ? 56.597  -30.905 31.301  1.00 58.84  ? 330 ASP C OD1 1 
ATOM   8691  O OD2 . ASP C 1 330 ? 56.212  -32.900 32.147  1.00 60.68  ? 330 ASP C OD2 1 
ATOM   8692  N N   . ASP C 1 331 ? 61.083  -33.556 31.377  1.00 39.66  ? 331 ASP C N   1 
ATOM   8693  C CA  . ASP C 1 331 ? 62.426  -34.008 31.720  1.00 44.08  ? 331 ASP C CA  1 
ATOM   8694  C C   . ASP C 1 331 ? 63.458  -33.635 30.681  1.00 36.33  ? 331 ASP C C   1 
ATOM   8695  O O   . ASP C 1 331 ? 64.613  -34.017 30.849  1.00 42.72  ? 331 ASP C O   1 
ATOM   8696  C CB  . ASP C 1 331 ? 62.439  -35.524 31.938  1.00 44.94  ? 331 ASP C CB  1 
ATOM   8697  C CG  . ASP C 1 331 ? 61.921  -36.288 30.738  1.00 44.79  ? 331 ASP C CG  1 
ATOM   8698  O OD1 . ASP C 1 331 ? 62.406  -36.011 29.630  1.00 45.75  ? 331 ASP C OD1 1 
ATOM   8699  O OD2 . ASP C 1 331 ? 61.031  -37.156 30.897  1.00 47.67  ? 331 ASP C OD2 1 
ATOM   8700  N N   . GLY C 1 332 ? 63.069  -32.926 29.621  1.00 40.90  ? 332 GLY C N   1 
ATOM   8701  C CA  . GLY C 1 332 ? 63.970  -32.526 28.556  1.00 42.80  ? 332 GLY C CA  1 
ATOM   8702  C C   . GLY C 1 332 ? 64.125  -33.528 27.430  1.00 41.79  ? 332 GLY C C   1 
ATOM   8703  O O   . GLY C 1 332 ? 64.889  -33.264 26.493  1.00 42.52  ? 332 GLY C O   1 
ATOM   8704  N N   . ARG C 1 333 ? 63.425  -34.663 27.487  1.00 42.27  ? 333 ARG C N   1 
ATOM   8705  C CA  . ARG C 1 333 ? 63.579  -35.711 26.482  1.00 41.04  ? 333 ARG C CA  1 
ATOM   8706  C C   . ARG C 1 333 ? 62.886  -35.332 25.179  1.00 34.60  ? 333 ARG C C   1 
ATOM   8707  O O   . ARG C 1 333 ? 61.801  -34.748 25.183  1.00 37.27  ? 333 ARG C O   1 
ATOM   8708  C CB  . ARG C 1 333 ? 62.999  -37.027 26.991  1.00 39.60  ? 333 ARG C CB  1 
ATOM   8709  C CG  . ARG C 1 333 ? 64.008  -37.955 27.612  1.00 34.41  ? 333 ARG C CG  1 
ATOM   8710  C CD  . ARG C 1 333 ? 63.377  -39.299 27.781  1.00 38.96  ? 333 ARG C CD  1 
ATOM   8711  N NE  . ARG C 1 333 ? 62.229  -39.214 28.673  1.00 44.85  ? 333 ARG C NE  1 
ATOM   8712  C CZ  . ARG C 1 333 ? 61.462  -40.244 29.002  1.00 46.21  ? 333 ARG C CZ  1 
ATOM   8713  N NH1 . ARG C 1 333 ? 61.684  -41.457 28.521  1.00 47.44  ? 333 ARG C NH1 1 
ATOM   8714  N NH2 . ARG C 1 333 ? 60.442  -40.051 29.830  1.00 52.45  ? 333 ARG C NH2 1 
ATOM   8715  N N   . VAL C 1 334 ? 63.505  -35.713 24.067  1.00 31.18  ? 334 VAL C N   1 
ATOM   8716  C CA  . VAL C 1 334 ? 63.062  -35.363 22.723  1.00 32.09  ? 334 VAL C CA  1 
ATOM   8717  C C   . VAL C 1 334 ? 62.566  -36.619 22.020  1.00 35.84  ? 334 VAL C C   1 
ATOM   8718  O O   . VAL C 1 334 ? 63.184  -37.686 22.134  1.00 33.19  ? 334 VAL C O   1 
ATOM   8719  C CB  . VAL C 1 334 ? 64.219  -34.725 21.930  1.00 36.19  ? 334 VAL C CB  1 
ATOM   8720  C CG1 . VAL C 1 334 ? 63.862  -34.585 20.447  1.00 29.96  ? 334 VAL C CG1 1 
ATOM   8721  C CG2 . VAL C 1 334 ? 64.623  -33.390 22.548  1.00 28.14  ? 334 VAL C CG2 1 
ATOM   8722  N N   . PHE C 1 335 ? 61.461  -36.494 21.288  1.00 25.23  ? 335 PHE C N   1 
ATOM   8723  C CA  . PHE C 1 335 ? 60.988  -37.571 20.430  1.00 31.51  ? 335 PHE C CA  1 
ATOM   8724  C C   . PHE C 1 335 ? 60.510  -36.972 19.114  1.00 29.20  ? 335 PHE C C   1 
ATOM   8725  O O   . PHE C 1 335 ? 59.843  -35.938 19.105  1.00 30.88  ? 335 PHE C O   1 
ATOM   8726  C CB  . PHE C 1 335 ? 59.841  -38.371 21.078  1.00 32.12  ? 335 PHE C CB  1 
ATOM   8727  C CG  . PHE C 1 335 ? 60.232  -39.128 22.320  1.00 34.87  ? 335 PHE C CG  1 
ATOM   8728  C CD1 . PHE C 1 335 ? 61.076  -40.229 22.253  1.00 37.19  ? 335 PHE C CD1 1 
ATOM   8729  C CD2 . PHE C 1 335 ? 59.738  -38.749 23.559  1.00 36.67  ? 335 PHE C CD2 1 
ATOM   8730  C CE1 . PHE C 1 335 ? 61.431  -40.933 23.408  1.00 32.50  ? 335 PHE C CE1 1 
ATOM   8731  C CE2 . PHE C 1 335 ? 60.088  -39.444 24.706  1.00 35.18  ? 335 PHE C CE2 1 
ATOM   8732  C CZ  . PHE C 1 335 ? 60.936  -40.538 24.627  1.00 35.39  ? 335 PHE C CZ  1 
ATOM   8733  N N   . PHE C 1 336 ? 60.846  -37.612 18.005  1.00 32.04  ? 336 PHE C N   1 
ATOM   8734  C CA  . PHE C 1 336 ? 60.290  -37.244 16.713  1.00 26.63  ? 336 PHE C CA  1 
ATOM   8735  C C   . PHE C 1 336 ? 59.267  -38.294 16.309  1.00 29.52  ? 336 PHE C C   1 
ATOM   8736  O O   . PHE C 1 336 ? 59.459  -39.486 16.574  1.00 27.61  ? 336 PHE C O   1 
ATOM   8737  C CB  . PHE C 1 336 ? 61.395  -37.106 15.677  1.00 32.40  ? 336 PHE C CB  1 
ATOM   8738  C CG  . PHE C 1 336 ? 62.392  -36.046 16.025  1.00 29.75  ? 336 PHE C CG  1 
ATOM   8739  C CD1 . PHE C 1 336 ? 62.142  -34.711 15.727  1.00 24.96  ? 336 PHE C CD1 1 
ATOM   8740  C CD2 . PHE C 1 336 ? 63.561  -36.370 16.677  1.00 30.20  ? 336 PHE C CD2 1 
ATOM   8741  C CE1 . PHE C 1 336 ? 63.043  -33.733 16.065  1.00 24.35  ? 336 PHE C CE1 1 
ATOM   8742  C CE2 . PHE C 1 336 ? 64.475  -35.380 17.011  1.00 30.85  ? 336 PHE C CE2 1 
ATOM   8743  C CZ  . PHE C 1 336 ? 64.212  -34.066 16.703  1.00 24.55  ? 336 PHE C CZ  1 
ATOM   8744  N N   . HIS C 1 337 ? 58.164  -37.839 15.703  1.00 31.55  ? 337 HIS C N   1 
ATOM   8745  C CA  . HIS C 1 337 ? 56.941  -38.621 15.506  1.00 28.69  ? 337 HIS C CA  1 
ATOM   8746  C C   . HIS C 1 337 ? 56.726  -39.101 14.072  1.00 29.56  ? 337 HIS C C   1 
ATOM   8747  O O   . HIS C 1 337 ? 56.378  -40.268 13.842  1.00 22.84  ? 337 HIS C O   1 
ATOM   8748  C CB  . HIS C 1 337 ? 55.723  -37.781 15.916  1.00 31.66  ? 337 HIS C CB  1 
ATOM   8749  C CG  . HIS C 1 337 ? 55.593  -37.572 17.391  1.00 35.68  ? 337 HIS C CG  1 
ATOM   8750  N ND1 . HIS C 1 337 ? 55.992  -38.515 18.319  1.00 38.02  ? 337 HIS C ND1 1 
ATOM   8751  C CD2 . HIS C 1 337 ? 55.086  -36.537 18.100  1.00 33.74  ? 337 HIS C CD2 1 
ATOM   8752  C CE1 . HIS C 1 337 ? 55.739  -38.066 19.537  1.00 39.29  ? 337 HIS C CE1 1 
ATOM   8753  N NE2 . HIS C 1 337 ? 55.189  -36.867 19.432  1.00 41.95  ? 337 HIS C NE2 1 
ATOM   8754  N N   . GLU C 1 338 ? 56.850  -38.203 13.100  1.00 30.08  ? 338 GLU C N   1 
ATOM   8755  C CA  . GLU C 1 338 ? 56.513  -38.530 11.722  1.00 31.12  ? 338 GLU C CA  1 
ATOM   8756  C C   . GLU C 1 338 ? 57.160  -37.511 10.805  1.00 26.95  ? 338 GLU C C   1 
ATOM   8757  O O   . GLU C 1 338 ? 57.557  -36.430 11.241  1.00 26.14  ? 338 GLU C O   1 
ATOM   8758  C CB  . GLU C 1 338 ? 54.998  -38.545 11.506  1.00 34.44  ? 338 GLU C CB  1 
ATOM   8759  C CG  . GLU C 1 338 ? 54.316  -37.260 11.926  1.00 32.74  ? 338 GLU C CG  1 
ATOM   8760  C CD  . GLU C 1 338 ? 52.822  -37.248 11.577  1.00 45.69  ? 338 GLU C CD  1 
ATOM   8761  O OE1 . GLU C 1 338 ? 52.175  -38.327 11.598  1.00 37.43  ? 338 GLU C OE1 1 
ATOM   8762  O OE2 . GLU C 1 338 ? 52.303  -36.145 11.276  1.00 49.08  ? 338 GLU C OE2 1 
ATOM   8763  N N   . ILE C 1 339 ? 57.272  -37.879 9.525   1.00 30.95  ? 339 ILE C N   1 
ATOM   8764  C CA  . ILE C 1 339 ? 57.682  -36.947 8.484   1.00 28.84  ? 339 ILE C CA  1 
ATOM   8765  C C   . ILE C 1 339 ? 56.574  -36.857 7.443   1.00 32.22  ? 339 ILE C C   1 
ATOM   8766  O O   . ILE C 1 339 ? 55.687  -37.718 7.346   1.00 29.92  ? 339 ILE C O   1 
ATOM   8767  C CB  . ILE C 1 339 ? 59.016  -37.329 7.811   1.00 27.45  ? 339 ILE C CB  1 
ATOM   8768  C CG1 . ILE C 1 339 ? 59.026  -38.800 7.433   1.00 25.78  ? 339 ILE C CG1 1 
ATOM   8769  C CG2 . ILE C 1 339 ? 60.213  -36.979 8.697   1.00 25.70  ? 339 ILE C CG2 1 
ATOM   8770  C CD1 . ILE C 1 339 ? 59.754  -39.040 6.143   1.00 21.63  ? 339 ILE C CD1 1 
ATOM   8771  N N   . ASN C 1 340 ? 56.646  -35.787 6.656   1.00 25.53  ? 340 ASN C N   1 
ATOM   8772  C CA  . ASN C 1 340 ? 55.701  -35.533 5.578   1.00 30.31  ? 340 ASN C CA  1 
ATOM   8773  C C   . ASN C 1 340 ? 56.475  -34.951 4.410   1.00 29.51  ? 340 ASN C C   1 
ATOM   8774  O O   . ASN C 1 340 ? 56.968  -33.821 4.493   1.00 26.29  ? 340 ASN C O   1 
ATOM   8775  C CB  . ASN C 1 340 ? 54.597  -34.572 6.019   1.00 32.61  ? 340 ASN C CB  1 
ATOM   8776  C CG  . ASN C 1 340 ? 53.594  -35.224 6.940   1.00 31.29  ? 340 ASN C CG  1 
ATOM   8777  O OD1 . ASN C 1 340 ? 52.845  -36.109 6.529   1.00 35.48  ? 340 ASN C OD1 1 
ATOM   8778  N ND2 . ASN C 1 340 ? 53.541  -34.758 8.182   1.00 35.65  ? 340 ASN C ND2 1 
ATOM   8779  N N   . ALA C 1 341 ? 56.562  -35.709 3.320   1.00 32.99  ? 341 ALA C N   1 
ATOM   8780  C CA  . ALA C 1 341 ? 57.217  -35.247 2.093   1.00 29.20  ? 341 ALA C CA  1 
ATOM   8781  C C   . ALA C 1 341 ? 56.168  -34.590 1.191   1.00 28.81  ? 341 ALA C C   1 
ATOM   8782  O O   . ALA C 1 341 ? 55.640  -35.182 0.245   1.00 29.25  ? 341 ALA C O   1 
ATOM   8783  C CB  . ALA C 1 341 ? 57.929  -36.404 1.405   1.00 29.14  ? 341 ALA C CB  1 
ATOM   8784  N N   . ARG C 1 342 ? 55.887  -33.325 1.497   1.00 31.32  ? 342 ARG C N   1 
ATOM   8785  C CA  . ARG C 1 342 ? 54.908  -32.467 0.827   1.00 27.45  ? 342 ARG C CA  1 
ATOM   8786  C C   . ARG C 1 342 ? 54.835  -31.186 1.648   1.00 26.59  ? 342 ARG C C   1 
ATOM   8787  O O   . ARG C 1 342 ? 55.414  -31.101 2.736   1.00 24.67  ? 342 ARG C O   1 
ATOM   8788  C CB  . ARG C 1 342 ? 53.529  -33.120 0.709   1.00 28.93  ? 342 ARG C CB  1 
ATOM   8789  C CG  . ARG C 1 342 ? 52.946  -33.528 2.037   1.00 29.48  ? 342 ARG C CG  1 
ATOM   8790  C CD  . ARG C 1 342 ? 51.438  -33.586 1.979   1.00 39.70  ? 342 ARG C CD  1 
ATOM   8791  N NE  . ARG C 1 342 ? 50.860  -33.971 3.261   1.00 38.46  ? 342 ARG C NE  1 
ATOM   8792  C CZ  . ARG C 1 342 ? 50.949  -35.187 3.787   1.00 48.52  ? 342 ARG C CZ  1 
ATOM   8793  N NH1 . ARG C 1 342 ? 51.571  -36.171 3.151   1.00 43.87  ? 342 ARG C NH1 1 
ATOM   8794  N NH2 . ARG C 1 342 ? 50.397  -35.424 4.980   1.00 50.87  ? 342 ARG C NH2 1 
ATOM   8795  N N   . TRP C 1 343 ? 54.128  -30.184 1.115   1.00 25.23  ? 343 TRP C N   1 
ATOM   8796  C CA  . TRP C 1 343 ? 53.950  -28.936 1.849   1.00 23.42  ? 343 TRP C CA  1 
ATOM   8797  C C   . TRP C 1 343 ? 53.371  -29.192 3.238   1.00 22.53  ? 343 TRP C C   1 
ATOM   8798  O O   . TRP C 1 343 ? 52.431  -29.973 3.408   1.00 23.50  ? 343 TRP C O   1 
ATOM   8799  C CB  . TRP C 1 343 ? 53.018  -27.994 1.088   1.00 25.57  ? 343 TRP C CB  1 
ATOM   8800  C CG  . TRP C 1 343 ? 53.498  -27.609 -0.276  1.00 29.12  ? 343 TRP C CG  1 
ATOM   8801  C CD1 . TRP C 1 343 ? 54.768  -27.718 -0.769  1.00 27.49  ? 343 TRP C CD1 1 
ATOM   8802  C CD2 . TRP C 1 343 ? 52.701  -27.053 -1.330  1.00 27.71  ? 343 TRP C CD2 1 
ATOM   8803  N NE1 . TRP C 1 343 ? 54.809  -27.252 -2.058  1.00 30.46  ? 343 TRP C NE1 1 
ATOM   8804  C CE2 . TRP C 1 343 ? 53.557  -26.832 -2.427  1.00 27.01  ? 343 TRP C CE2 1 
ATOM   8805  C CE3 . TRP C 1 343 ? 51.342  -26.715 -1.447  1.00 28.55  ? 343 TRP C CE3 1 
ATOM   8806  C CZ2 . TRP C 1 343 ? 53.102  -26.310 -3.644  1.00 27.78  ? 343 TRP C CZ2 1 
ATOM   8807  C CZ3 . TRP C 1 343 ? 50.888  -26.181 -2.656  1.00 29.38  ? 343 TRP C CZ3 1 
ATOM   8808  C CH2 . TRP C 1 343 ? 51.769  -25.984 -3.736  1.00 30.71  ? 343 TRP C CH2 1 
ATOM   8809  N N   . SER C 1 344 ? 53.950  -28.549 4.243   1.00 18.86  ? 344 SER C N   1 
ATOM   8810  C CA  . SER C 1 344 ? 53.238  -28.451 5.501   1.00 20.95  ? 344 SER C CA  1 
ATOM   8811  C C   . SER C 1 344 ? 52.129  -27.409 5.356   1.00 23.98  ? 344 SER C C   1 
ATOM   8812  O O   . SER C 1 344 ? 52.104  -26.638 4.405   1.00 21.30  ? 344 SER C O   1 
ATOM   8813  C CB  . SER C 1 344 ? 54.190  -28.051 6.624   1.00 24.36  ? 344 SER C CB  1 
ATOM   8814  O OG  . SER C 1 344 ? 54.488  -26.661 6.529   1.00 23.56  ? 344 SER C OG  1 
ATOM   8815  N N   . GLY C 1 345 ? 51.224  -27.364 6.328   1.00 27.41  ? 345 GLY C N   1 
ATOM   8816  C CA  . GLY C 1 345 ? 50.239  -26.298 6.342   1.00 22.48  ? 345 GLY C CA  1 
ATOM   8817  C C   . GLY C 1 345 ? 50.858  -24.924 6.517   1.00 22.71  ? 345 GLY C C   1 
ATOM   8818  O O   . GLY C 1 345 ? 50.300  -23.929 6.054   1.00 26.61  ? 345 GLY C O   1 
ATOM   8819  N N   . GLY C 1 346 ? 52.026  -24.848 7.151   1.00 22.93  ? 346 GLY C N   1 
ATOM   8820  C CA  . GLY C 1 346 ? 52.650  -23.585 7.488   1.00 22.29  ? 346 GLY C CA  1 
ATOM   8821  C C   . GLY C 1 346 ? 53.669  -23.046 6.517   1.00 25.10  ? 346 GLY C C   1 
ATOM   8822  O O   . GLY C 1 346 ? 54.220  -21.957 6.745   1.00 26.11  ? 346 GLY C O   1 
ATOM   8823  N N   . LEU C 1 347 ? 53.939  -23.774 5.436   1.00 24.16  ? 347 LEU C N   1 
ATOM   8824  C CA  . LEU C 1 347 ? 54.877  -23.308 4.427   1.00 18.93  ? 347 LEU C CA  1 
ATOM   8825  C C   . LEU C 1 347 ? 54.422  -21.987 3.826   1.00 19.96  ? 347 LEU C C   1 
ATOM   8826  O O   . LEU C 1 347 ? 55.242  -21.117 3.512   1.00 24.84  ? 347 LEU C O   1 
ATOM   8827  C CB  . LEU C 1 347 ? 55.027  -24.376 3.336   1.00 16.14  ? 347 LEU C CB  1 
ATOM   8828  C CG  . LEU C 1 347 ? 55.938  -23.994 2.160   1.00 23.77  ? 347 LEU C CG  1 
ATOM   8829  C CD1 . LEU C 1 347 ? 57.350  -23.564 2.630   1.00 16.49  ? 347 LEU C CD1 1 
ATOM   8830  C CD2 . LEU C 1 347 ? 56.029  -25.112 1.127   1.00 20.63  ? 347 LEU C CD2 1 
ATOM   8831  N N   . ILE C 1 348 ? 53.122  -21.824 3.639   1.00 17.74  ? 348 ILE C N   1 
ATOM   8832  C CA  . ILE C 1 348 ? 52.658  -20.579 3.063   1.00 20.94  ? 348 ILE C CA  1 
ATOM   8833  C C   . ILE C 1 348 ? 52.745  -19.482 4.107   1.00 17.94  ? 348 ILE C C   1 
ATOM   8834  O O   . ILE C 1 348 ? 53.020  -18.331 3.772   1.00 19.90  ? 348 ILE C O   1 
ATOM   8835  C CB  . ILE C 1 348 ? 51.243  -20.766 2.473   1.00 20.51  ? 348 ILE C CB  1 
ATOM   8836  C CG1 . ILE C 1 348 ? 50.838  -19.561 1.633   1.00 20.70  ? 348 ILE C CG1 1 
ATOM   8837  C CG2 . ILE C 1 348 ? 50.216  -21.114 3.545   1.00 18.48  ? 348 ILE C CG2 1 
ATOM   8838  C CD1 . ILE C 1 348 ? 51.701  -19.379 0.409   1.00 22.54  ? 348 ILE C CD1 1 
ATOM   8839  N N   . TYR C 1 349 ? 52.597  -19.820 5.392   1.00 17.70  ? 349 TYR C N   1 
ATOM   8840  C CA  . TYR C 1 349 ? 52.818  -18.815 6.427   1.00 20.28  ? 349 TYR C CA  1 
ATOM   8841  C C   . TYR C 1 349 ? 54.258  -18.347 6.417   1.00 23.53  ? 349 TYR C C   1 
ATOM   8842  O O   . TYR C 1 349 ? 54.539  -17.147 6.552   1.00 23.07  ? 349 TYR C O   1 
ATOM   8843  C CB  . TYR C 1 349 ? 52.500  -19.352 7.818   1.00 19.15  ? 349 TYR C CB  1 
ATOM   8844  C CG  . TYR C 1 349 ? 51.148  -19.958 8.022   1.00 21.47  ? 349 TYR C CG  1 
ATOM   8845  C CD1 . TYR C 1 349 ? 50.088  -19.663 7.165   1.00 21.38  ? 349 TYR C CD1 1 
ATOM   8846  C CD2 . TYR C 1 349 ? 50.911  -20.817 9.104   1.00 22.94  ? 349 TYR C CD2 1 
ATOM   8847  C CE1 . TYR C 1 349 ? 48.844  -20.211 7.363   1.00 17.49  ? 349 TYR C CE1 1 
ATOM   8848  C CE2 . TYR C 1 349 ? 49.663  -21.373 9.310   1.00 25.38  ? 349 TYR C CE2 1 
ATOM   8849  C CZ  . TYR C 1 349 ? 48.629  -21.054 8.429   1.00 25.88  ? 349 TYR C CZ  1 
ATOM   8850  O OH  . TYR C 1 349 ? 47.369  -21.568 8.612   1.00 25.75  ? 349 TYR C OH  1 
ATOM   8851  N N   . HIS C 1 350 ? 55.194  -19.291 6.311   1.00 23.53  ? 350 HIS C N   1 
ATOM   8852  C CA  . HIS C 1 350 ? 56.595  -18.906 6.262   1.00 20.63  ? 350 HIS C CA  1 
ATOM   8853  C C   . HIS C 1 350 ? 56.868  -18.091 4.999   1.00 21.52  ? 350 HIS C C   1 
ATOM   8854  O O   . HIS C 1 350 ? 57.620  -17.111 5.034   1.00 19.30  ? 350 HIS C O   1 
ATOM   8855  C CB  . HIS C 1 350 ? 57.477  -20.158 6.362   1.00 17.80  ? 350 HIS C CB  1 
ATOM   8856  C CG  . HIS C 1 350 ? 58.900  -19.942 5.953   1.00 18.13  ? 350 HIS C CG  1 
ATOM   8857  N ND1 . HIS C 1 350 ? 59.812  -19.280 6.748   1.00 21.11  ? 350 HIS C ND1 1 
ATOM   8858  C CD2 . HIS C 1 350 ? 59.566  -20.294 4.829   1.00 17.59  ? 350 HIS C CD2 1 
ATOM   8859  C CE1 . HIS C 1 350 ? 60.982  -19.242 6.134   1.00 20.21  ? 350 HIS C CE1 1 
ATOM   8860  N NE2 . HIS C 1 350 ? 60.861  -19.860 4.974   1.00 20.81  ? 350 HIS C NE2 1 
ATOM   8861  N N   . THR C 1 351 ? 56.195  -18.426 3.894   1.00 21.81  ? 351 THR C N   1 
ATOM   8862  C CA  . THR C 1 351 ? 56.419  -17.691 2.654   1.00 19.32  ? 351 THR C CA  1 
ATOM   8863  C C   . THR C 1 351 ? 55.942  -16.240 2.760   1.00 21.18  ? 351 THR C C   1 
ATOM   8864  O O   . THR C 1 351 ? 56.633  -15.316 2.318   1.00 20.42  ? 351 THR C O   1 
ATOM   8865  C CB  . THR C 1 351 ? 55.720  -18.392 1.490   1.00 19.20  ? 351 THR C CB  1 
ATOM   8866  O OG1 . THR C 1 351 ? 56.150  -19.754 1.390   1.00 22.93  ? 351 THR C OG1 1 
ATOM   8867  C CG2 . THR C 1 351 ? 55.992  -17.652 0.185   1.00 22.07  ? 351 THR C CG2 1 
ATOM   8868  N N   . VAL C 1 352 ? 54.735  -16.021 3.287   1.00 21.75  ? 352 VAL C N   1 
ATOM   8869  C CA  . VAL C 1 352 ? 54.245  -14.656 3.475   1.00 17.61  ? 352 VAL C CA  1 
ATOM   8870  C C   . VAL C 1 352 ? 55.151  -13.900 4.441   1.00 24.63  ? 352 VAL C C   1 
ATOM   8871  O O   . VAL C 1 352 ? 55.498  -12.727 4.220   1.00 22.59  ? 352 VAL C O   1 
ATOM   8872  C CB  . VAL C 1 352 ? 52.781  -14.672 3.969   1.00 20.99  ? 352 VAL C CB  1 
ATOM   8873  C CG1 . VAL C 1 352 ? 52.262  -13.269 4.141   1.00 22.81  ? 352 VAL C CG1 1 
ATOM   8874  C CG2 . VAL C 1 352 ? 51.900  -15.414 3.012   1.00 19.35  ? 352 VAL C CG2 1 
ATOM   8875  N N   . ALA C 1 353 ? 55.540  -14.557 5.535   1.00 23.80  ? 353 ALA C N   1 
ATOM   8876  C CA  . ALA C 1 353 ? 56.431  -13.927 6.499   1.00 23.94  ? 353 ALA C CA  1 
ATOM   8877  C C   . ALA C 1 353 ? 57.662  -13.369 5.805   1.00 22.12  ? 353 ALA C C   1 
ATOM   8878  O O   . ALA C 1 353 ? 58.019  -12.201 5.999   1.00 23.60  ? 353 ALA C O   1 
ATOM   8879  C CB  . ALA C 1 353 ? 56.822  -14.928 7.589   1.00 19.29  ? 353 ALA C CB  1 
ATOM   8880  N N   . GLU C 1 354 ? 58.288  -14.167 4.940   1.00 17.61  ? 354 GLU C N   1 
ATOM   8881  C CA  . GLU C 1 354 ? 59.521  -13.709 4.286   1.00 22.92  ? 354 GLU C CA  1 
ATOM   8882  C C   . GLU C 1 354 ? 59.264  -12.569 3.314   1.00 21.24  ? 354 GLU C C   1 
ATOM   8883  O O   . GLU C 1 354 ? 60.071  -11.639 3.219   1.00 25.25  ? 354 GLU C O   1 
ATOM   8884  C CB  . GLU C 1 354 ? 60.220  -14.865 3.557   1.00 20.14  ? 354 GLU C CB  1 
ATOM   8885  C CG  . GLU C 1 354 ? 60.975  -15.787 4.512   1.00 29.73  ? 354 GLU C CG  1 
ATOM   8886  C CD  . GLU C 1 354 ? 62.012  -16.676 3.836   1.00 31.60  ? 354 GLU C CD  1 
ATOM   8887  O OE1 . GLU C 1 354 ? 61.757  -17.164 2.709   1.00 27.03  ? 354 GLU C OE1 1 
ATOM   8888  O OE2 . GLU C 1 354 ? 63.081  -16.897 4.460   1.00 33.59  ? 354 GLU C OE2 1 
ATOM   8889  N N   . ARG C 1 355 ? 58.176  -12.641 2.551   1.00 21.65  ? 355 ARG C N   1 
ATOM   8890  C CA  . ARG C 1 355 ? 57.904  -11.608 1.557   1.00 21.89  ? 355 ARG C CA  1 
ATOM   8891  C C   . ARG C 1 355 ? 57.499  -10.295 2.203   1.00 28.98  ? 355 ARG C C   1 
ATOM   8892  O O   . ARG C 1 355 ? 57.789  -9.218  1.659   1.00 32.01  ? 355 ARG C O   1 
ATOM   8893  C CB  . ARG C 1 355 ? 56.811  -12.083 0.605   1.00 20.72  ? 355 ARG C CB  1 
ATOM   8894  C CG  . ARG C 1 355 ? 57.222  -13.343 -0.126  1.00 26.48  ? 355 ARG C CG  1 
ATOM   8895  C CD  . ARG C 1 355 ? 56.164  -13.784 -1.098  1.00 29.30  ? 355 ARG C CD  1 
ATOM   8896  N NE  . ARG C 1 355 ? 56.124  -12.958 -2.299  1.00 33.59  ? 355 ARG C NE  1 
ATOM   8897  C CZ  . ARG C 1 355 ? 55.428  -13.275 -3.381  1.00 33.52  ? 355 ARG C CZ  1 
ATOM   8898  N NH1 . ARG C 1 355 ? 54.716  -14.396 -3.440  1.00 27.86  ? 355 ARG C NH1 1 
ATOM   8899  N NH2 . ARG C 1 355 ? 55.428  -12.442 -4.419  1.00 34.29  ? 355 ARG C NH2 1 
ATOM   8900  N N   . LEU C 1 356 ? 56.814  -10.358 3.343   1.00 21.85  ? 356 LEU C N   1 
ATOM   8901  C CA  . LEU C 1 356 ? 56.307  -9.146  3.958   1.00 22.89  ? 356 LEU C CA  1 
ATOM   8902  C C   . LEU C 1 356 ? 57.313  -8.563  4.927   1.00 25.91  ? 356 LEU C C   1 
ATOM   8903  O O   . LEU C 1 356 ? 57.499  -7.345  4.969   1.00 27.89  ? 356 LEU C O   1 
ATOM   8904  C CB  . LEU C 1 356 ? 54.991  -9.435  4.687   1.00 28.24  ? 356 LEU C CB  1 
ATOM   8905  C CG  . LEU C 1 356 ? 53.776  -9.769  3.823   1.00 25.58  ? 356 LEU C CG  1 
ATOM   8906  C CD1 . LEU C 1 356 ? 52.494  -9.670  4.654   1.00 24.36  ? 356 LEU C CD1 1 
ATOM   8907  C CD2 . LEU C 1 356 ? 53.737  -8.839  2.628   1.00 27.08  ? 356 LEU C CD2 1 
ATOM   8908  N N   . LEU C 1 357 ? 57.982  -9.423  5.690   1.00 23.95  ? 357 LEU C N   1 
ATOM   8909  C CA  . LEU C 1 357 ? 58.892  -8.994  6.737   1.00 24.58  ? 357 LEU C CA  1 
ATOM   8910  C C   . LEU C 1 357 ? 60.355  -9.266  6.439   1.00 25.69  ? 357 LEU C C   1 
ATOM   8911  O O   . LEU C 1 357 ? 61.203  -8.760  7.173   1.00 28.61  ? 357 LEU C O   1 
ATOM   8912  C CB  . LEU C 1 357 ? 58.549  -9.699  8.059   1.00 23.81  ? 357 LEU C CB  1 
ATOM   8913  C CG  . LEU C 1 357 ? 57.079  -9.633  8.451   1.00 26.62  ? 357 LEU C CG  1 
ATOM   8914  C CD1 . LEU C 1 357 ? 56.868  -10.477 9.659   1.00 24.92  ? 357 LEU C CD1 1 
ATOM   8915  C CD2 . LEU C 1 357 ? 56.670  -8.179  8.718   1.00 25.64  ? 357 LEU C CD2 1 
ATOM   8916  N N   . GLY C 1 358 ? 60.677  -10.111 5.451   1.00 23.05  ? 358 GLY C N   1 
ATOM   8917  C CA  . GLY C 1 358 ? 62.069  -10.339 5.088   1.00 28.87  ? 358 GLY C CA  1 
ATOM   8918  C C   . GLY C 1 358 ? 62.640  -11.635 5.638   1.00 25.22  ? 358 GLY C C   1 
ATOM   8919  O O   . GLY C 1 358 ? 62.019  -12.357 6.424   1.00 27.59  ? 358 GLY C O   1 
ATOM   8920  N N   . HIS C 1 359 ? 63.893  -11.888 5.243   1.00 30.90  ? 359 HIS C N   1 
ATOM   8921  C CA  . HIS C 1 359 ? 64.484  -13.228 5.280   1.00 29.37  ? 359 HIS C CA  1 
ATOM   8922  C C   . HIS C 1 359 ? 64.871  -13.718 6.674   1.00 33.54  ? 359 HIS C C   1 
ATOM   8923  O O   . HIS C 1 359 ? 65.016  -14.930 6.871   1.00 36.76  ? 359 HIS C O   1 
ATOM   8924  C CB  . HIS C 1 359 ? 65.729  -13.266 4.404   1.00 34.77  ? 359 HIS C CB  1 
ATOM   8925  C CG  . HIS C 1 359 ? 65.468  -13.651 2.981   1.00 37.21  ? 359 HIS C CG  1 
ATOM   8926  N ND1 . HIS C 1 359 ? 66.264  -13.216 1.943   1.00 44.17  ? 359 HIS C ND1 1 
ATOM   8927  C CD2 . HIS C 1 359 ? 64.537  -14.461 2.428   1.00 37.77  ? 359 HIS C CD2 1 
ATOM   8928  C CE1 . HIS C 1 359 ? 65.822  -13.726 0.807   1.00 46.72  ? 359 HIS C CE1 1 
ATOM   8929  N NE2 . HIS C 1 359 ? 64.775  -14.487 1.075   1.00 43.80  ? 359 HIS C NE2 1 
ATOM   8930  N N   . ASP C 1 360 ? 65.100  -12.858 7.640   1.00 27.61  ? 360 ASP C N   1 
ATOM   8931  C CA  . ASP C 1 360 ? 65.375  -13.422 8.962   1.00 33.25  ? 360 ASP C CA  1 
ATOM   8932  C C   . ASP C 1 360 ? 64.273  -13.040 9.947   1.00 29.62  ? 360 ASP C C   1 
ATOM   8933  O O   . ASP C 1 360 ? 64.522  -12.808 11.136  1.00 26.76  ? 360 ASP C O   1 
ATOM   8934  C CB  . ASP C 1 360 ? 66.765  -13.012 9.458   1.00 35.09  ? 360 ASP C CB  1 
ATOM   8935  C CG  . ASP C 1 360 ? 67.878  -13.858 8.827   1.00 36.50  ? 360 ASP C CG  1 
ATOM   8936  O OD1 . ASP C 1 360 ? 67.967  -15.063 9.152   1.00 32.49  ? 360 ASP C OD1 1 
ATOM   8937  O OD2 . ASP C 1 360 ? 68.638  -13.330 7.981   1.00 32.11  ? 360 ASP C OD2 1 
ATOM   8938  N N   . TYR C 1 361 ? 63.029  -13.014 9.441   1.00 21.89  ? 361 TYR C N   1 
ATOM   8939  C CA  . TYR C 1 361 ? 61.901  -12.501 10.200  1.00 21.98  ? 361 TYR C CA  1 
ATOM   8940  C C   . TYR C 1 361 ? 61.781  -13.165 11.566  1.00 26.05  ? 361 TYR C C   1 
ATOM   8941  O O   . TYR C 1 361 ? 61.403  -12.514 12.544  1.00 22.62  ? 361 TYR C O   1 
ATOM   8942  C CB  . TYR C 1 361 ? 60.611  -12.682 9.395   1.00 23.62  ? 361 TYR C CB  1 
ATOM   8943  C CG  . TYR C 1 361 ? 60.137  -14.124 9.307   1.00 26.49  ? 361 TYR C CG  1 
ATOM   8944  C CD1 . TYR C 1 361 ? 59.384  -14.700 10.330  1.00 20.20  ? 361 TYR C CD1 1 
ATOM   8945  C CD2 . TYR C 1 361 ? 60.443  -14.911 8.194   1.00 22.83  ? 361 TYR C CD2 1 
ATOM   8946  C CE1 . TYR C 1 361 ? 58.975  -16.013 10.253  1.00 23.18  ? 361 TYR C CE1 1 
ATOM   8947  C CE2 . TYR C 1 361 ? 60.025  -16.210 8.109   1.00 19.94  ? 361 TYR C CE2 1 
ATOM   8948  C CZ  . TYR C 1 361 ? 59.296  -16.761 9.139   1.00 20.66  ? 361 TYR C CZ  1 
ATOM   8949  O OH  . TYR C 1 361 ? 58.880  -18.066 9.058   1.00 27.44  ? 361 TYR C OH  1 
ATOM   8950  N N   . ALA C 1 362 ? 62.107  -14.460 11.661  1.00 22.16  ? 362 ALA C N   1 
ATOM   8951  C CA  . ALA C 1 362 ? 61.844  -15.168 12.909  1.00 26.85  ? 362 ALA C CA  1 
ATOM   8952  C C   . ALA C 1 362 ? 62.685  -14.652 14.057  1.00 27.26  ? 362 ALA C C   1 
ATOM   8953  O O   . ALA C 1 362 ? 62.373  -14.952 15.209  1.00 28.87  ? 362 ALA C O   1 
ATOM   8954  C CB  . ALA C 1 362 ? 62.083  -16.675 12.772  1.00 30.07  ? 362 ALA C CB  1 
ATOM   8955  N N   . ARG C 1 363 ? 63.732  -13.885 13.782  1.00 26.69  ? 363 ARG C N   1 
ATOM   8956  C CA  . ARG C 1 363 ? 64.535  -13.390 14.883  1.00 34.17  ? 363 ARG C CA  1 
ATOM   8957  C C   . ARG C 1 363 ? 63.937  -12.145 15.532  1.00 36.94  ? 363 ARG C C   1 
ATOM   8958  O O   . ARG C 1 363 ? 64.281  -11.829 16.675  1.00 28.61  ? 363 ARG C O   1 
ATOM   8959  C CB  . ARG C 1 363 ? 65.955  -13.126 14.397  1.00 34.86  ? 363 ARG C CB  1 
ATOM   8960  C CG  . ARG C 1 363 ? 66.640  -14.390 13.891  1.00 35.93  ? 363 ARG C CG  1 
ATOM   8961  C CD  . ARG C 1 363 ? 67.961  -14.089 13.185  1.00 36.57  ? 363 ARG C CD  1 
ATOM   8962  N NE  . ARG C 1 363 ? 68.726  -15.302 12.899  1.00 37.53  ? 363 ARG C NE  1 
ATOM   8963  C CZ  . ARG C 1 363 ? 69.851  -15.323 12.193  1.00 35.73  ? 363 ARG C CZ  1 
ATOM   8964  N NH1 . ARG C 1 363 ? 70.348  -14.218 11.654  1.00 37.84  ? 363 ARG C NH1 1 
ATOM   8965  N NH2 . ARG C 1 363 ? 70.506  -16.476 12.049  1.00 31.36  ? 363 ARG C NH2 1 
ATOM   8966  N N   . ASN C 1 364 ? 63.025  -11.451 14.851  1.00 28.50  ? 364 ASN C N   1 
ATOM   8967  C CA  . ASN C 1 364 ? 62.479  -10.241 15.450  1.00 34.45  ? 364 ASN C CA  1 
ATOM   8968  C C   . ASN C 1 364 ? 60.968  -10.143 15.282  1.00 33.18  ? 364 ASN C C   1 
ATOM   8969  O O   . ASN C 1 364 ? 60.415  -9.042  15.430  1.00 27.41  ? 364 ASN C O   1 
ATOM   8970  C CB  . ASN C 1 364 ? 63.173  -9.003  14.850  1.00 36.50  ? 364 ASN C CB  1 
ATOM   8971  C CG  . ASN C 1 364 ? 64.613  -8.872  15.320  1.00 41.79  ? 364 ASN C CG  1 
ATOM   8972  O OD1 . ASN C 1 364 ? 64.877  -8.733  16.516  1.00 46.93  ? 364 ASN C OD1 1 
ATOM   8973  N ND2 . ASN C 1 364 ? 65.550  -8.957  14.390  1.00 41.32  ? 364 ASN C ND2 1 
ATOM   8974  N N   . ASN C 1 365 ? 60.293  -11.260 14.976  1.00 28.85  ? 365 ASN C N   1 
ATOM   8975  C CA  . ASN C 1 365 ? 58.868  -11.235 14.682  1.00 25.24  ? 365 ASN C CA  1 
ATOM   8976  C C   . ASN C 1 365 ? 58.185  -12.510 15.140  1.00 30.33  ? 365 ASN C C   1 
ATOM   8977  O O   . ASN C 1 365 ? 58.820  -13.545 15.375  1.00 29.56  ? 365 ASN C O   1 
ATOM   8978  C CB  . ASN C 1 365 ? 58.609  -11.044 13.195  1.00 29.63  ? 365 ASN C CB  1 
ATOM   8979  C CG  . ASN C 1 365 ? 59.164  -9.753  12.694  1.00 29.82  ? 365 ASN C CG  1 
ATOM   8980  O OD1 . ASN C 1 365 ? 58.582  -8.692  12.917  1.00 31.41  ? 365 ASN C OD1 1 
ATOM   8981  N ND2 . ASN C 1 365 ? 60.328  -9.820  12.066  1.00 25.89  ? 365 ASN C ND2 1 
ATOM   8982  N N   . PHE C 1 366 ? 56.866  -12.415 15.250  1.00 23.54  ? 366 PHE C N   1 
ATOM   8983  C CA  . PHE C 1 366 ? 56.014  -13.553 15.523  1.00 25.21  ? 366 PHE C CA  1 
ATOM   8984  C C   . PHE C 1 366 ? 54.876  -13.567 14.516  1.00 26.75  ? 366 PHE C C   1 
ATOM   8985  O O   . PHE C 1 366 ? 54.454  -12.526 13.996  1.00 23.35  ? 366 PHE C O   1 
ATOM   8986  C CB  . PHE C 1 366 ? 55.436  -13.504 16.944  1.00 25.16  ? 366 PHE C CB  1 
ATOM   8987  C CG  . PHE C 1 366 ? 56.473  -13.458 18.010  1.00 26.97  ? 366 PHE C CG  1 
ATOM   8988  C CD1 . PHE C 1 366 ? 57.020  -14.626 18.513  1.00 31.89  ? 366 PHE C CD1 1 
ATOM   8989  C CD2 . PHE C 1 366 ? 56.917  -12.245 18.507  1.00 30.37  ? 366 PHE C CD2 1 
ATOM   8990  C CE1 . PHE C 1 366 ? 57.984  -14.588 19.501  1.00 31.02  ? 366 PHE C CE1 1 
ATOM   8991  C CE2 . PHE C 1 366 ? 57.879  -12.199 19.501  1.00 34.57  ? 366 PHE C CE2 1 
ATOM   8992  C CZ  . PHE C 1 366 ? 58.417  -13.374 19.998  1.00 33.64  ? 366 PHE C CZ  1 
ATOM   8993  N N   . PHE C 1 367 ? 54.373  -14.758 14.240  1.00 19.40  ? 367 PHE C N   1 
ATOM   8994  C CA  . PHE C 1 367 ? 53.161  -14.844 13.470  1.00 27.73  ? 367 PHE C CA  1 
ATOM   8995  C C   . PHE C 1 367 ? 52.338  -16.001 13.997  1.00 28.34  ? 367 PHE C C   1 
ATOM   8996  O O   . PHE C 1 367 ? 52.847  -16.911 14.658  1.00 27.07  ? 367 PHE C O   1 
ATOM   8997  C CB  . PHE C 1 367 ? 53.426  -14.920 11.941  1.00 26.65  ? 367 PHE C CB  1 
ATOM   8998  C CG  . PHE C 1 367 ? 53.901  -16.259 11.415  1.00 22.36  ? 367 PHE C CG  1 
ATOM   8999  C CD1 . PHE C 1 367 ? 53.054  -17.339 11.336  1.00 20.70  ? 367 PHE C CD1 1 
ATOM   9000  C CD2 . PHE C 1 367 ? 55.175  -16.378 10.874  1.00 25.36  ? 367 PHE C CD2 1 
ATOM   9001  C CE1 . PHE C 1 367 ? 53.488  -18.528 10.804  1.00 25.90  ? 367 PHE C CE1 1 
ATOM   9002  C CE2 . PHE C 1 367 ? 55.625  -17.571 10.335  1.00 20.08  ? 367 PHE C CE2 1 
ATOM   9003  C CZ  . PHE C 1 367 ? 54.785  -18.646 10.292  1.00 26.40  ? 367 PHE C CZ  1 
ATOM   9004  N N   . SER C 1 368 ? 51.045  -15.925 13.706  1.00 25.56  ? 368 SER C N   1 
ATOM   9005  C CA  . SER C 1 368 ? 50.072  -16.880 14.193  1.00 28.90  ? 368 SER C CA  1 
ATOM   9006  C C   . SER C 1 368 ? 48.910  -16.902 13.220  1.00 27.32  ? 368 SER C C   1 
ATOM   9007  O O   . SER C 1 368 ? 48.476  -15.850 12.735  1.00 29.38  ? 368 SER C O   1 
ATOM   9008  C CB  . SER C 1 368 ? 49.596  -16.512 15.602  1.00 33.51  ? 368 SER C CB  1 
ATOM   9009  O OG  . SER C 1 368 ? 48.758  -17.518 16.132  1.00 36.67  ? 368 SER C OG  1 
ATOM   9010  N N   . SER C 1 369 ? 48.417  -18.099 12.939  1.00 28.29  ? 369 SER C N   1 
ATOM   9011  C CA  . SER C 1 369 ? 47.253  -18.288 12.092  1.00 28.47  ? 369 SER C CA  1 
ATOM   9012  C C   . SER C 1 369 ? 46.031  -18.523 12.966  1.00 28.88  ? 369 SER C C   1 
ATOM   9013  O O   . SER C 1 369 ? 46.155  -18.916 14.128  1.00 30.81  ? 369 SER C O   1 
ATOM   9014  C CB  . SER C 1 369 ? 47.450  -19.454 11.118  1.00 27.14  ? 369 SER C CB  1 
ATOM   9015  O OG  . SER C 1 369 ? 47.502  -20.705 11.791  1.00 27.59  ? 369 SER C OG  1 
ATOM   9016  N N   . ILE C 1 370 ? 44.860  -18.212 12.400  1.00 27.60  ? 370 ILE C N   1 
ATOM   9017  C CA  . ILE C 1 370 ? 43.536  -18.471 12.973  1.00 26.82  ? 370 ILE C CA  1 
ATOM   9018  C C   . ILE C 1 370 ? 42.732  -19.158 11.872  1.00 29.77  ? 370 ILE C C   1 
ATOM   9019  O O   . ILE C 1 370 ? 42.442  -18.548 10.831  1.00 26.10  ? 370 ILE C O   1 
ATOM   9020  C CB  . ILE C 1 370 ? 42.819  -17.190 13.441  1.00 29.73  ? 370 ILE C CB  1 
ATOM   9021  C CG1 . ILE C 1 370 ? 43.699  -16.352 14.351  1.00 26.58  ? 370 ILE C CG1 1 
ATOM   9022  C CG2 . ILE C 1 370 ? 41.532  -17.517 14.183  1.00 27.97  ? 370 ILE C CG2 1 
ATOM   9023  C CD1 . ILE C 1 370 ? 43.205  -14.928 14.455  1.00 24.64  ? 370 ILE C CD1 1 
ATOM   9024  N N   . LEU C 1 371 ? 42.414  -20.430 12.068  1.00 30.40  ? 371 LEU C N   1 
ATOM   9025  C CA  . LEU C 1 371 ? 41.645  -21.148 11.072  1.00 33.76  ? 371 LEU C CA  1 
ATOM   9026  C C   . LEU C 1 371 ? 40.154  -20.983 11.296  1.00 32.15  ? 371 LEU C C   1 
ATOM   9027  O O   . LEU C 1 371 ? 39.370  -21.377 10.429  1.00 29.29  ? 371 LEU C O   1 
ATOM   9028  C CB  . LEU C 1 371 ? 42.021  -22.639 11.085  1.00 37.27  ? 371 LEU C CB  1 
ATOM   9029  C CG  . LEU C 1 371 ? 43.491  -22.969 10.827  1.00 37.43  ? 371 LEU C CG  1 
ATOM   9030  C CD1 . LEU C 1 371 ? 43.780  -24.451 11.059  1.00 35.99  ? 371 LEU C CD1 1 
ATOM   9031  C CD2 . LEU C 1 371 ? 43.868  -22.559 9.416   1.00 30.27  ? 371 LEU C CD2 1 
ATOM   9032  N N   . ASN C 1 372 ? 39.791  -20.306 12.391  1.00 40.44  ? 372 ASN C N   1 
ATOM   9033  C CA  . ASN C 1 372 ? 38.530  -20.344 13.125  1.00 40.23  ? 372 ASN C CA  1 
ATOM   9034  C C   . ASN C 1 372 ? 37.526  -19.277 12.721  1.00 31.78  ? 372 ASN C C   1 
ATOM   9035  O O   . ASN C 1 372 ? 36.378  -19.343 13.169  1.00 34.91  ? 372 ASN C O   1 
ATOM   9036  C CB  . ASN C 1 372 ? 38.811  -20.129 14.615  1.00 33.19  ? 372 ASN C CB  1 
ATOM   9037  C CG  . ASN C 1 372 ? 39.015  -21.397 15.343  1.00 41.79  ? 372 ASN C CG  1 
ATOM   9038  O OD1 . ASN C 1 372 ? 38.077  -21.986 15.877  1.00 39.98  ? 372 ASN C OD1 1 
ATOM   9039  N ND2 . ASN C 1 372 ? 40.261  -21.846 15.377  1.00 47.46  ? 372 ASN C ND2 1 
ATOM   9040  N N   . VAL C 1 373 ? 37.941  -18.272 11.953  1.00 30.68  ? 373 VAL C N   1 
ATOM   9041  C CA  . VAL C 1 373 ? 37.125  -17.076 11.790  1.00 32.77  ? 373 VAL C CA  1 
ATOM   9042  C C   . VAL C 1 373 ? 35.809  -17.419 11.103  1.00 33.43  ? 373 VAL C C   1 
ATOM   9043  O O   . VAL C 1 373 ? 35.741  -18.308 10.244  1.00 28.32  ? 373 VAL C O   1 
ATOM   9044  C CB  . VAL C 1 373 ? 37.915  -16.012 11.008  1.00 32.97  ? 373 VAL C CB  1 
ATOM   9045  C CG1 . VAL C 1 373 ? 37.183  -14.689 11.004  1.00 32.21  ? 373 VAL C CG1 1 
ATOM   9046  C CG2 . VAL C 1 373 ? 39.323  -15.854 11.598  1.00 26.27  ? 373 VAL C CG2 1 
ATOM   9047  N N   . VAL C 1 374 ? 34.747  -16.720 11.495  1.00 37.40  ? 374 VAL C N   1 
ATOM   9048  C CA  . VAL C 1 374 ? 33.441  -16.892 10.865  1.00 29.43  ? 374 VAL C CA  1 
ATOM   9049  C C   . VAL C 1 374 ? 33.560  -16.548 9.384   1.00 28.51  ? 374 VAL C C   1 
ATOM   9050  O O   . VAL C 1 374 ? 33.888  -15.405 9.051   1.00 31.55  ? 374 VAL C O   1 
ATOM   9051  C CB  . VAL C 1 374 ? 32.373  -16.014 11.536  1.00 36.02  ? 374 VAL C CB  1 
ATOM   9052  C CG1 . VAL C 1 374 ? 31.105  -15.981 10.670  1.00 31.25  ? 374 VAL C CG1 1 
ATOM   9053  C CG2 . VAL C 1 374 ? 32.075  -16.490 12.957  1.00 29.23  ? 374 VAL C CG2 1 
ATOM   9054  N N   . PRO C 1 375 ? 33.285  -17.481 8.473   1.00 29.69  ? 375 PRO C N   1 
ATOM   9055  C CA  . PRO C 1 375 ? 33.441  -17.199 7.036   1.00 32.32  ? 375 PRO C CA  1 
ATOM   9056  C C   . PRO C 1 375 ? 32.688  -15.952 6.581   1.00 30.82  ? 375 PRO C C   1 
ATOM   9057  O O   . PRO C 1 375 ? 31.555  -15.702 6.988   1.00 32.28  ? 375 PRO C O   1 
ATOM   9058  C CB  . PRO C 1 375 ? 32.876  -18.460 6.371   1.00 31.55  ? 375 PRO C CB  1 
ATOM   9059  C CG  . PRO C 1 375 ? 33.108  -19.549 7.377   1.00 35.63  ? 375 PRO C CG  1 
ATOM   9060  C CD  . PRO C 1 375 ? 32.951  -18.893 8.734   1.00 31.20  ? 375 PRO C CD  1 
ATOM   9061  N N   . ALA C 1 376 ? 33.322  -15.174 5.705   1.00 33.01  ? 376 ALA C N   1 
ATOM   9062  C CA  . ALA C 1 376 ? 32.689  -13.979 5.158   1.00 34.81  ? 376 ALA C CA  1 
ATOM   9063  C C   . ALA C 1 376 ? 33.306  -13.692 3.808   1.00 31.20  ? 376 ALA C C   1 
ATOM   9064  O O   . ALA C 1 376 ? 34.307  -14.302 3.428   1.00 36.89  ? 376 ALA C O   1 
ATOM   9065  C CB  . ALA C 1 376 ? 32.846  -12.768 6.091   1.00 29.55  ? 376 ALA C CB  1 
ATOM   9066  N N   . GLY C 1 377 ? 32.710  -12.742 3.087   1.00 33.83  ? 377 GLY C N   1 
ATOM   9067  C CA  . GLY C 1 377 ? 33.309  -12.274 1.848   1.00 29.61  ? 377 GLY C CA  1 
ATOM   9068  C C   . GLY C 1 377 ? 34.573  -11.474 2.103   1.00 31.74  ? 377 GLY C C   1 
ATOM   9069  O O   . GLY C 1 377 ? 34.749  -10.878 3.166   1.00 31.78  ? 377 GLY C O   1 
ATOM   9070  N N   . LEU C 1 378 ? 35.475  -11.475 1.108   1.00 30.69  ? 378 LEU C N   1 
ATOM   9071  C CA  . LEU C 1 378 ? 36.729  -10.728 1.222   1.00 28.46  ? 378 LEU C CA  1 
ATOM   9072  C C   . LEU C 1 378 ? 36.489  -9.276  1.615   1.00 28.82  ? 378 LEU C C   1 
ATOM   9073  O O   . LEU C 1 378 ? 37.187  -8.733  2.485   1.00 31.75  ? 378 LEU C O   1 
ATOM   9074  C CB  . LEU C 1 378 ? 37.504  -10.768 -0.092  1.00 30.59  ? 378 LEU C CB  1 
ATOM   9075  C CG  . LEU C 1 378 ? 38.815  -10.030 0.116   1.00 23.48  ? 378 LEU C CG  1 
ATOM   9076  C CD1 . LEU C 1 378 ? 39.571  -10.761 1.198   1.00 24.61  ? 378 LEU C CD1 1 
ATOM   9077  C CD2 . LEU C 1 378 ? 39.656  -9.929  -1.120  1.00 31.34  ? 378 LEU C CD2 1 
ATOM   9078  N N   . ALA C 1 379 ? 35.517  -8.627  0.971   1.00 27.22  ? 379 ALA C N   1 
ATOM   9079  C CA  . ALA C 1 379 ? 35.116  -7.281  1.374   1.00 31.18  ? 379 ALA C CA  1 
ATOM   9080  C C   . ALA C 1 379 ? 34.907  -7.181  2.882   1.00 32.80  ? 379 ALA C C   1 
ATOM   9081  O O   . ALA C 1 379 ? 35.481  -6.303  3.542   1.00 28.11  ? 379 ALA C O   1 
ATOM   9082  C CB  . ALA C 1 379 ? 33.844  -6.873  0.629   1.00 33.40  ? 379 ALA C CB  1 
ATOM   9083  N N   . ASP C 1 380 ? 34.118  -8.103  3.457   1.00 31.35  ? 380 ASP C N   1 
ATOM   9084  C CA  . ASP C 1 380 ? 33.730  -7.965  4.861   1.00 29.86  ? 380 ASP C CA  1 
ATOM   9085  C C   . ASP C 1 380 ? 34.863  -8.324  5.819   1.00 28.89  ? 380 ASP C C   1 
ATOM   9086  O O   . ASP C 1 380 ? 35.021  -7.679  6.862   1.00 34.79  ? 380 ASP C O   1 
ATOM   9087  C CB  . ASP C 1 380 ? 32.513  -8.832  5.157   1.00 33.19  ? 380 ASP C CB  1 
ATOM   9088  C CG  . ASP C 1 380 ? 31.241  -8.294  4.528   1.00 39.66  ? 380 ASP C CG  1 
ATOM   9089  O OD1 . ASP C 1 380 ? 30.870  -7.123  4.797   1.00 41.55  ? 380 ASP C OD1 1 
ATOM   9090  O OD2 . ASP C 1 380 ? 30.600  -9.061  3.776   1.00 38.07  ? 380 ASP C OD2 1 
ATOM   9091  N N   . LEU C 1 381 ? 35.642  -9.361  5.513   1.00 27.68  ? 381 LEU C N   1 
ATOM   9092  C CA  . LEU C 1 381 ? 36.790  -9.691  6.351   1.00 28.07  ? 381 LEU C CA  1 
ATOM   9093  C C   . LEU C 1 381 ? 37.746  -8.503  6.464   1.00 22.79  ? 381 LEU C C   1 
ATOM   9094  O O   . LEU C 1 381 ? 38.027  -8.019  7.564   1.00 21.50  ? 381 LEU C O   1 
ATOM   9095  C CB  . LEU C 1 381 ? 37.511  -10.916 5.792   1.00 26.61  ? 381 LEU C CB  1 
ATOM   9096  C CG  . LEU C 1 381 ? 36.764  -12.243 5.925   1.00 35.34  ? 381 LEU C CG  1 
ATOM   9097  C CD1 . LEU C 1 381 ? 37.462  -13.305 5.104   1.00 31.40  ? 381 LEU C CD1 1 
ATOM   9098  C CD2 . LEU C 1 381 ? 36.671  -12.667 7.373   1.00 30.18  ? 381 LEU C CD2 1 
ATOM   9099  N N   . LEU C 1 382 ? 38.248  -8.016  5.326   1.00 20.72  ? 382 LEU C N   1 
ATOM   9100  C CA  . LEU C 1 382 ? 39.084  -6.814  5.325   1.00 23.35  ? 382 LEU C CA  1 
ATOM   9101  C C   . LEU C 1 382 ? 38.446  -5.680  6.126   1.00 23.63  ? 382 LEU C C   1 
ATOM   9102  O O   . LEU C 1 382 ? 39.122  -5.009  6.918   1.00 24.13  ? 382 LEU C O   1 
ATOM   9103  C CB  . LEU C 1 382 ? 39.354  -6.369  3.884   1.00 22.36  ? 382 LEU C CB  1 
ATOM   9104  C CG  . LEU C 1 382 ? 40.238  -7.330  3.089   1.00 22.88  ? 382 LEU C CG  1 
ATOM   9105  C CD1 . LEU C 1 382 ? 40.416  -6.892  1.659   1.00 23.45  ? 382 LEU C CD1 1 
ATOM   9106  C CD2 . LEU C 1 382 ? 41.596  -7.473  3.766   1.00 27.96  ? 382 LEU C CD2 1 
ATOM   9107  N N   . ARG C 1 383 ? 37.134  -5.476  5.956   1.00 23.72  ? 383 ARG C N   1 
ATOM   9108  C CA  . ARG C 1 383 ? 36.416  -4.501  6.779   1.00 25.62  ? 383 ARG C CA  1 
ATOM   9109  C C   . ARG C 1 383 ? 36.554  -4.811  8.264   1.00 25.89  ? 383 ARG C C   1 
ATOM   9110  O O   . ARG C 1 383 ? 36.774  -3.900  9.070   1.00 25.29  ? 383 ARG C O   1 
ATOM   9111  C CB  . ARG C 1 383 ? 34.933  -4.454  6.386   1.00 29.82  ? 383 ARG C CB  1 
ATOM   9112  C CG  . ARG C 1 383 ? 34.140  -3.253  6.950   1.00 30.77  ? 383 ARG C CG  1 
ATOM   9113  C CD  . ARG C 1 383 ? 34.802  -1.895  6.629   1.00 30.96  ? 383 ARG C CD  1 
ATOM   9114  N NE  . ARG C 1 383 ? 34.916  -1.104  7.849   1.00 39.98  ? 383 ARG C NE  1 
ATOM   9115  C CZ  . ARG C 1 383 ? 35.886  -0.248  8.126   1.00 33.36  ? 383 ARG C CZ  1 
ATOM   9116  N NH1 . ARG C 1 383 ? 36.879  -0.026  7.285   1.00 31.99  ? 383 ARG C NH1 1 
ATOM   9117  N NH2 . ARG C 1 383 ? 35.854  0.408   9.279   1.00 39.06  ? 383 ARG C NH2 1 
ATOM   9118  N N   . SER C 1 384 ? 36.432  -6.091  8.649   1.00 27.79  ? 384 SER C N   1 
ATOM   9119  C CA  . SER C 1 384 ? 36.517  -6.454  10.069  1.00 28.70  ? 384 SER C CA  1 
ATOM   9120  C C   . SER C 1 384 ? 37.913  -6.222  10.618  1.00 26.69  ? 384 SER C C   1 
ATOM   9121  O O   . SER C 1 384 ? 38.081  -5.848  11.788  1.00 25.00  ? 384 SER C O   1 
ATOM   9122  C CB  . SER C 1 384 ? 36.128  -7.919  10.282  1.00 24.88  ? 384 SER C CB  1 
ATOM   9123  O OG  . SER C 1 384 ? 34.783  -8.042  10.680  1.00 34.13  ? 384 SER C OG  1 
ATOM   9124  N N   . LEU C 1 385 ? 38.931  -6.484  9.801   1.00 26.14  ? 385 LEU C N   1 
ATOM   9125  C CA  . LEU C 1 385 ? 40.298  -6.205  10.220  1.00 28.41  ? 385 LEU C CA  1 
ATOM   9126  C C   . LEU C 1 385 ? 40.538  -4.705  10.415  1.00 27.11  ? 385 LEU C C   1 
ATOM   9127  O O   . LEU C 1 385 ? 41.282  -4.314  11.319  1.00 26.37  ? 385 LEU C O   1 
ATOM   9128  C CB  . LEU C 1 385 ? 41.275  -6.783  9.203   1.00 21.64  ? 385 LEU C CB  1 
ATOM   9129  C CG  . LEU C 1 385 ? 41.282  -8.297  8.980   1.00 25.93  ? 385 LEU C CG  1 
ATOM   9130  C CD1 . LEU C 1 385 ? 42.318  -8.646  7.918   1.00 23.96  ? 385 LEU C CD1 1 
ATOM   9131  C CD2 . LEU C 1 385 ? 41.626  -8.943  10.275  1.00 21.27  ? 385 LEU C CD2 1 
ATOM   9132  N N   . GLU C 1 386 ? 39.960  -3.848  9.560   1.00 23.47  ? 386 GLU C N   1 
ATOM   9133  C CA  . GLU C 1 386 ? 40.124  -2.404  9.772   1.00 24.70  ? 386 GLU C CA  1 
ATOM   9134  C C   . GLU C 1 386 ? 39.404  -1.937  11.029  1.00 23.68  ? 386 GLU C C   1 
ATOM   9135  O O   . GLU C 1 386 ? 39.910  -1.081  11.758  1.00 22.60  ? 386 GLU C O   1 
ATOM   9136  C CB  . GLU C 1 386 ? 39.628  -1.621  8.562   1.00 28.12  ? 386 GLU C CB  1 
ATOM   9137  C CG  . GLU C 1 386 ? 40.431  -1.950  7.338   1.00 29.09  ? 386 GLU C CG  1 
ATOM   9138  C CD  . GLU C 1 386 ? 40.076  -1.137  6.122   1.00 35.73  ? 386 GLU C CD  1 
ATOM   9139  O OE1 . GLU C 1 386 ? 39.709  0.063   6.266   1.00 32.00  ? 386 GLU C OE1 1 
ATOM   9140  O OE2 . GLU C 1 386 ? 40.161  -1.738  5.016   1.00 31.45  ? 386 GLU C OE2 1 
ATOM   9141  N N   . ARG C 1 387 ? 38.236  -2.509  11.311  1.00 27.94  ? 387 ARG C N   1 
ATOM   9142  C CA  . ARG C 1 387 ? 37.475  -2.113  12.490  1.00 30.20  ? 387 ARG C CA  1 
ATOM   9143  C C   . ARG C 1 387 ? 38.235  -2.435  13.777  1.00 30.59  ? 387 ARG C C   1 
ATOM   9144  O O   . ARG C 1 387 ? 38.159  -1.688  14.760  1.00 32.16  ? 387 ARG C O   1 
ATOM   9145  C CB  . ARG C 1 387 ? 36.107  -2.792  12.464  1.00 24.70  ? 387 ARG C CB  1 
ATOM   9146  C CG  . ARG C 1 387 ? 35.234  -2.467  13.671  1.00 39.49  ? 387 ARG C CG  1 
ATOM   9147  C CD  . ARG C 1 387 ? 33.974  -3.332  13.705  1.00 34.51  ? 387 ARG C CD  1 
ATOM   9148  N NE  . ARG C 1 387 ? 33.321  -3.364  12.406  1.00 32.82  ? 387 ARG C NE  1 
ATOM   9149  C CZ  . ARG C 1 387 ? 33.140  -4.450  11.664  1.00 37.94  ? 387 ARG C CZ  1 
ATOM   9150  N NH1 . ARG C 1 387 ? 33.540  -5.644  12.068  1.00 36.40  ? 387 ARG C NH1 1 
ATOM   9151  N NH2 . ARG C 1 387 ? 32.530  -4.333  10.485  1.00 39.39  ? 387 ARG C NH2 1 
ATOM   9152  N N   . ALA C 1 388 ? 38.984  -3.531  13.787  1.00 31.60  ? 388 ALA C N   1 
ATOM   9153  C CA  . ALA C 1 388 ? 39.793  -3.861  14.953  1.00 35.45  ? 388 ALA C CA  1 
ATOM   9154  C C   . ALA C 1 388 ? 41.106  -3.097  14.989  1.00 32.38  ? 388 ALA C C   1 
ATOM   9155  O O   . ALA C 1 388 ? 41.768  -3.098  16.035  1.00 35.39  ? 388 ALA C O   1 
ATOM   9156  C CB  . ALA C 1 388 ? 40.080  -5.370  15.000  1.00 36.73  ? 388 ALA C CB  1 
ATOM   9157  N N   . GLY C 1 389 ? 41.477  -2.440  13.886  1.00 27.84  ? 389 GLY C N   1 
ATOM   9158  C CA  . GLY C 1 389 ? 42.748  -1.747  13.787  1.00 27.09  ? 389 GLY C CA  1 
ATOM   9159  C C   . GLY C 1 389 ? 43.932  -2.663  13.565  1.00 32.76  ? 389 GLY C C   1 
ATOM   9160  O O   . GLY C 1 389 ? 45.042  -2.360  14.015  1.00 29.29  ? 389 GLY C O   1 
ATOM   9161  N N   . VAL C 1 390 ? 43.733  -3.788  12.875  1.00 32.41  ? 390 VAL C N   1 
ATOM   9162  C CA  . VAL C 1 390 ? 44.796  -4.776  12.751  1.00 30.93  ? 390 VAL C CA  1 
ATOM   9163  C C   . VAL C 1 390 ? 44.945  -5.266  11.321  1.00 32.16  ? 390 VAL C C   1 
ATOM   9164  O O   . VAL C 1 390 ? 45.631  -6.265  11.093  1.00 30.31  ? 390 VAL C O   1 
ATOM   9165  C CB  . VAL C 1 390 ? 44.559  -5.973  13.689  1.00 32.09  ? 390 VAL C CB  1 
ATOM   9166  C CG1 . VAL C 1 390 ? 44.529  -5.523  15.154  1.00 33.61  ? 390 VAL C CG1 1 
ATOM   9167  C CG2 . VAL C 1 390 ? 43.268  -6.707  13.298  1.00 24.65  ? 390 VAL C CG2 1 
ATOM   9168  N N   . ARG C 1 391 ? 44.307  -4.600  10.353  1.00 26.36  ? 391 ARG C N   1 
ATOM   9169  C CA  . ARG C 1 391 ? 44.600  -4.931  8.965   1.00 29.52  ? 391 ARG C CA  1 
ATOM   9170  C C   . ARG C 1 391 ? 46.096  -4.762  8.742   1.00 31.90  ? 391 ARG C C   1 
ATOM   9171  O O   . ARG C 1 391 ? 46.691  -3.800  9.232   1.00 28.49  ? 391 ARG C O   1 
ATOM   9172  C CB  . ARG C 1 391 ? 43.819  -4.040  7.998   1.00 26.93  ? 391 ARG C CB  1 
ATOM   9173  C CG  . ARG C 1 391 ? 44.228  -4.249  6.543   1.00 25.18  ? 391 ARG C CG  1 
ATOM   9174  C CD  . ARG C 1 391 ? 43.125  -3.913  5.527   1.00 27.79  ? 391 ARG C CD  1 
ATOM   9175  N NE  . ARG C 1 391 ? 43.579  -4.144  4.158   1.00 25.63  ? 391 ARG C NE  1 
ATOM   9176  C CZ  . ARG C 1 391 ? 42.904  -3.811  3.064   1.00 28.42  ? 391 ARG C CZ  1 
ATOM   9177  N NH1 . ARG C 1 391 ? 41.722  -3.218  3.129   1.00 24.17  ? 391 ARG C NH1 1 
ATOM   9178  N NH2 . ARG C 1 391 ? 43.431  -4.071  1.872   1.00 25.00  ? 391 ARG C NH2 1 
ATOM   9179  N N   . TYR C 1 392 ? 46.715  -5.725  8.050   1.00 26.59  ? 392 TYR C N   1 
ATOM   9180  C CA  . TYR C 1 392 ? 48.166  -5.696  7.901   1.00 25.05  ? 392 TYR C CA  1 
ATOM   9181  C C   . TYR C 1 392 ? 48.618  -4.339  7.387   1.00 27.43  ? 392 TYR C C   1 
ATOM   9182  O O   . TYR C 1 392 ? 48.129  -3.851  6.360   1.00 29.24  ? 392 TYR C O   1 
ATOM   9183  C CB  . TYR C 1 392 ? 48.671  -6.784  6.956   1.00 21.99  ? 392 TYR C CB  1 
ATOM   9184  C CG  . TYR C 1 392 ? 50.169  -6.689  6.780   1.00 29.28  ? 392 TYR C CG  1 
ATOM   9185  C CD1 . TYR C 1 392 ? 51.040  -7.086  7.807   1.00 24.31  ? 392 TYR C CD1 1 
ATOM   9186  C CD2 . TYR C 1 392 ? 50.718  -6.135  5.630   1.00 20.70  ? 392 TYR C CD2 1 
ATOM   9187  C CE1 . TYR C 1 392 ? 52.407  -6.971  7.662   1.00 26.68  ? 392 TYR C CE1 1 
ATOM   9188  C CE2 . TYR C 1 392 ? 52.081  -6.010  5.482   1.00 25.84  ? 392 TYR C CE2 1 
ATOM   9189  C CZ  . TYR C 1 392 ? 52.924  -6.438  6.494   1.00 29.46  ? 392 TYR C CZ  1 
ATOM   9190  O OH  . TYR C 1 392 ? 54.285  -6.321  6.344   1.00 28.92  ? 392 TYR C OH  1 
ATOM   9191  N N   . ASP C 1 393 ? 49.576  -3.759  8.106   1.00 25.68  ? 393 ASP C N   1 
ATOM   9192  C CA  . ASP C 1 393 ? 50.139  -2.434  7.864   1.00 27.39  ? 393 ASP C CA  1 
ATOM   9193  C C   . ASP C 1 393 ? 51.579  -2.604  7.382   1.00 28.76  ? 393 ASP C C   1 
ATOM   9194  O O   . ASP C 1 393 ? 52.457  -3.010  8.154   1.00 26.71  ? 393 ASP C O   1 
ATOM   9195  C CB  . ASP C 1 393 ? 50.078  -1.607  9.149   1.00 26.16  ? 393 ASP C CB  1 
ATOM   9196  C CG  . ASP C 1 393 ? 50.446  -0.140  8.937   1.00 36.94  ? 393 ASP C CG  1 
ATOM   9197  O OD1 . ASP C 1 393 ? 51.363  0.152   8.140   1.00 38.20  ? 393 ASP C OD1 1 
ATOM   9198  O OD2 . ASP C 1 393 ? 49.807  0.728   9.575   1.00 47.06  ? 393 ASP C OD2 1 
ATOM   9199  N N   . LYS C 1 394 ? 51.823  -2.273  6.113   1.00 25.83  ? 394 LYS C N   1 
ATOM   9200  C CA  . LYS C 1 394 ? 53.154  -2.423  5.535   1.00 31.29  ? 394 LYS C CA  1 
ATOM   9201  C C   . LYS C 1 394 ? 54.162  -1.405  6.070   1.00 36.15  ? 394 LYS C C   1 
ATOM   9202  O O   . LYS C 1 394 ? 55.366  -1.581  5.856   1.00 38.96  ? 394 LYS C O   1 
ATOM   9203  C CB  . LYS C 1 394 ? 53.070  -2.317  4.011   1.00 31.56  ? 394 LYS C CB  1 
ATOM   9204  C CG  . LYS C 1 394 ? 52.775  -0.899  3.524   1.00 40.06  ? 394 LYS C CG  1 
ATOM   9205  C CD  . LYS C 1 394 ? 53.000  -0.759  2.023   1.00 51.83  ? 394 LYS C CD  1 
ATOM   9206  C CE  . LYS C 1 394 ? 54.469  -0.509  1.684   1.00 50.63  ? 394 LYS C CE  1 
ATOM   9207  N NZ  . LYS C 1 394 ? 54.608  0.359   0.470   1.00 51.60  ? 394 LYS C NZ  1 
ATOM   9208  N N   . ASP C 1 395 ? 53.725  -0.341  6.747   1.00 34.12  ? 395 ASP C N   1 
ATOM   9209  C CA  . ASP C 1 395 ? 54.712  0.565   7.334   1.00 38.05  ? 395 ASP C CA  1 
ATOM   9210  C C   . ASP C 1 395 ? 55.228  0.056   8.673   1.00 34.73  ? 395 ASP C C   1 
ATOM   9211  O O   . ASP C 1 395 ? 56.361  0.362   9.048   1.00 34.66  ? 395 ASP C O   1 
ATOM   9212  C CB  . ASP C 1 395 ? 54.126  1.962   7.515   1.00 37.27  ? 395 ASP C CB  1 
ATOM   9213  C CG  . ASP C 1 395 ? 53.659  2.561   6.207   1.00 47.02  ? 395 ASP C CG  1 
ATOM   9214  O OD1 . ASP C 1 395 ? 54.282  2.260   5.154   1.00 43.74  ? 395 ASP C OD1 1 
ATOM   9215  O OD2 . ASP C 1 395 ? 52.660  3.314   6.239   1.00 45.50  ? 395 ASP C OD2 1 
ATOM   9216  N N   . SER C 1 396 ? 54.417  -0.702  9.406   1.00 34.00  ? 396 SER C N   1 
ATOM   9217  C CA  . SER C 1 396 ? 54.819  -1.238  10.695  1.00 34.17  ? 396 SER C CA  1 
ATOM   9218  C C   . SER C 1 396 ? 55.156  -2.726  10.664  1.00 35.87  ? 396 SER C C   1 
ATOM   9219  O O   . SER C 1 396 ? 55.836  -3.207  11.577  1.00 29.54  ? 396 SER C O   1 
ATOM   9220  C CB  . SER C 1 396 ? 53.714  -0.999  11.729  1.00 33.55  ? 396 SER C CB  1 
ATOM   9221  O OG  . SER C 1 396 ? 52.597  -1.836  11.470  1.00 35.35  ? 396 SER C OG  1 
ATOM   9222  N N   . GLY C 1 397 ? 54.708  -3.461  9.647   1.00 32.46  ? 397 GLY C N   1 
ATOM   9223  C CA  . GLY C 1 397 ? 54.909  -4.896  9.652   1.00 28.92  ? 397 GLY C CA  1 
ATOM   9224  C C   . GLY C 1 397 ? 54.017  -5.648  10.612  1.00 35.10  ? 397 GLY C C   1 
ATOM   9225  O O   . GLY C 1 397 ? 54.342  -6.782  10.990  1.00 33.52  ? 397 GLY C O   1 
ATOM   9226  N N   . GLU C 1 398 ? 52.892  -5.058  11.017  1.00 25.01  ? 398 GLU C N   1 
ATOM   9227  C CA  . GLU C 1 398 ? 52.020  -5.645  12.024  1.00 28.95  ? 398 GLU C CA  1 
ATOM   9228  C C   . GLU C 1 398 ? 50.637  -5.859  11.435  1.00 30.06  ? 398 GLU C C   1 
ATOM   9229  O O   . GLU C 1 398 ? 50.189  -5.106  10.561  1.00 25.29  ? 398 GLU C O   1 
ATOM   9230  C CB  . GLU C 1 398 ? 51.902  -4.755  13.292  1.00 30.78  ? 398 GLU C CB  1 
ATOM   9231  C CG  . GLU C 1 398 ? 53.246  -4.351  13.965  1.00 36.19  ? 398 GLU C CG  1 
ATOM   9232  C CD  . GLU C 1 398 ? 53.529  -5.048  15.307  1.00 38.97  ? 398 GLU C CD  1 
ATOM   9233  O OE1 . GLU C 1 398 ? 52.569  -5.353  16.052  1.00 43.17  ? 398 GLU C OE1 1 
ATOM   9234  O OE2 . GLU C 1 398 ? 54.722  -5.249  15.653  1.00 38.25  ? 398 GLU C OE2 1 
ATOM   9235  N N   . GLY C 1 399 ? 49.962  -6.880  11.925  1.00 28.34  ? 399 GLY C N   1 
ATOM   9236  C CA  . GLY C 1 399 ? 48.584  -7.103  11.560  1.00 30.87  ? 399 GLY C CA  1 
ATOM   9237  C C   . GLY C 1 399 ? 48.400  -8.358  10.731  1.00 28.80  ? 399 GLY C C   1 
ATOM   9238  O O   . GLY C 1 399 ? 49.289  -9.207  10.612  1.00 26.49  ? 399 GLY C O   1 
ATOM   9239  N N   . ALA C 1 400 ? 47.223  -8.441  10.128  1.00 23.90  ? 400 ALA C N   1 
ATOM   9240  C CA  . ALA C 1 400 ? 46.681  -9.677  9.598   1.00 26.10  ? 400 ALA C CA  1 
ATOM   9241  C C   . ALA C 1 400 ? 46.451  -9.567  8.103   1.00 25.66  ? 400 ALA C C   1 
ATOM   9242  O O   . ALA C 1 400 ? 46.150  -8.485  7.585   1.00 24.11  ? 400 ALA C O   1 
ATOM   9243  C CB  . ALA C 1 400 ? 45.356  -10.034 10.285  1.00 24.65  ? 400 ALA C CB  1 
ATOM   9244  N N   . VAL C 1 401 ? 46.587  -10.711 7.425   1.00 20.82  ? 401 VAL C N   1 
ATOM   9245  C CA  . VAL C 1 401 ? 46.240  -10.871 6.021   1.00 22.93  ? 401 VAL C CA  1 
ATOM   9246  C C   . VAL C 1 401 ? 45.294  -12.059 5.899   1.00 23.07  ? 401 VAL C C   1 
ATOM   9247  O O   . VAL C 1 401 ? 45.253  -12.939 6.759   1.00 23.00  ? 401 VAL C O   1 
ATOM   9248  C CB  . VAL C 1 401 ? 47.471  -11.102 5.133   1.00 25.05  ? 401 VAL C CB  1 
ATOM   9249  C CG1 . VAL C 1 401 ? 48.310  -9.855  5.069   1.00 25.11  ? 401 VAL C CG1 1 
ATOM   9250  C CG2 . VAL C 1 401 ? 48.262  -12.268 5.676   1.00 26.15  ? 401 VAL C CG2 1 
ATOM   9251  N N   . VAL C 1 402 ? 44.552  -12.085 4.795   1.00 24.07  ? 402 VAL C N   1 
ATOM   9252  C CA  . VAL C 1 402 ? 43.538  -13.103 4.523   1.00 21.18  ? 402 VAL C CA  1 
ATOM   9253  C C   . VAL C 1 402 ? 44.134  -14.181 3.626   1.00 25.03  ? 402 VAL C C   1 
ATOM   9254  O O   . VAL C 1 402 ? 44.550  -13.899 2.497   1.00 22.33  ? 402 VAL C O   1 
ATOM   9255  C CB  . VAL C 1 402 ? 42.300  -12.484 3.854   1.00 26.95  ? 402 VAL C CB  1 
ATOM   9256  C CG1 . VAL C 1 402 ? 41.278  -13.558 3.493   1.00 25.71  ? 402 VAL C CG1 1 
ATOM   9257  C CG2 . VAL C 1 402 ? 41.705  -11.389 4.728   1.00 22.19  ? 402 VAL C CG2 1 
ATOM   9258  N N   . LEU C 1 403 ? 44.119  -15.427 4.099   1.00 27.34  ? 403 LEU C N   1 
ATOM   9259  C CA  . LEU C 1 403 ? 44.500  -16.564 3.269   1.00 28.22  ? 403 LEU C CA  1 
ATOM   9260  C C   . LEU C 1 403 ? 43.305  -17.278 2.666   1.00 27.43  ? 403 LEU C C   1 
ATOM   9261  O O   . LEU C 1 403 ? 43.473  -18.028 1.705   1.00 27.18  ? 403 LEU C O   1 
ATOM   9262  C CB  . LEU C 1 403 ? 45.313  -17.592 4.075   1.00 25.25  ? 403 LEU C CB  1 
ATOM   9263  C CG  . LEU C 1 403 ? 46.641  -17.155 4.715   1.00 30.65  ? 403 LEU C CG  1 
ATOM   9264  C CD1 . LEU C 1 403 ? 47.632  -18.302 4.740   1.00 29.84  ? 403 LEU C CD1 1 
ATOM   9265  C CD2 . LEU C 1 403 ? 47.250  -15.952 4.026   1.00 27.60  ? 403 LEU C CD2 1 
ATOM   9266  N N   . GLY C 1 404 ? 42.120  -17.095 3.226   1.00 28.93  ? 404 GLY C N   1 
ATOM   9267  C CA  . GLY C 1 404 ? 40.940  -17.785 2.750   1.00 24.06  ? 404 GLY C CA  1 
ATOM   9268  C C   . GLY C 1 404 ? 39.681  -17.214 3.381   1.00 30.91  ? 404 GLY C C   1 
ATOM   9269  O O   . GLY C 1 404 ? 39.647  -16.953 4.592   1.00 27.52  ? 404 GLY C O   1 
ATOM   9270  N N   . CYS C 1 405 ? 38.649  -17.003 2.565   1.00 24.87  ? 405 CYS C N   1 
ATOM   9271  C CA  . CYS C 1 405 ? 37.390  -16.461 3.056   1.00 30.54  ? 405 CYS C CA  1 
ATOM   9272  C C   . CYS C 1 405 ? 36.465  -17.546 3.588   1.00 30.38  ? 405 CYS C C   1 
ATOM   9273  O O   . CYS C 1 405 ? 35.664  -17.281 4.493   1.00 28.14  ? 405 CYS C O   1 
ATOM   9274  C CB  . CYS C 1 405 ? 36.695  -15.679 1.938   1.00 30.10  ? 405 CYS C CB  1 
ATOM   9275  S SG  . CYS C 1 405 ? 37.643  -14.238 1.330   1.00 38.11  ? 405 CYS C SG  1 
ATOM   9276  N N   . ASN C 1 406 ? 36.610  -18.777 3.089   1.00 31.14  ? 406 ASN C N   1 
ATOM   9277  C CA  . ASN C 1 406 ? 35.675  -19.856 3.376   1.00 28.12  ? 406 ASN C CA  1 
ATOM   9278  C C   . ASN C 1 406 ? 36.362  -21.204 3.161   1.00 30.49  ? 406 ASN C C   1 
ATOM   9279  O O   . ASN C 1 406 ? 36.093  -21.910 2.186   1.00 31.74  ? 406 ASN C O   1 
ATOM   9280  C CB  . ASN C 1 406 ? 34.440  -19.698 2.484   1.00 30.69  ? 406 ASN C CB  1 
ATOM   9281  C CG  . ASN C 1 406 ? 33.312  -20.627 2.871   1.00 28.42  ? 406 ASN C CG  1 
ATOM   9282  O OD1 . ASN C 1 406 ? 33.042  -20.839 4.047   1.00 29.83  ? 406 ASN C OD1 1 
ATOM   9283  N ND2 . ASN C 1 406 ? 32.634  -21.169 1.874   1.00 25.73  ? 406 ASN C ND2 1 
ATOM   9284  N N   . SER C 1 407 ? 37.268  -21.551 4.060   1.00 31.17  ? 407 SER C N   1 
ATOM   9285  C CA  . SER C 1 407 ? 38.150  -22.698 3.924   1.00 33.61  ? 407 SER C CA  1 
ATOM   9286  C C   . SER C 1 407 ? 37.696  -23.819 4.850   1.00 33.66  ? 407 SER C C   1 
ATOM   9287  O O   . SER C 1 407 ? 37.139  -23.565 5.921   1.00 34.86  ? 407 SER C O   1 
ATOM   9288  C CB  . SER C 1 407 ? 39.588  -22.277 4.258   1.00 27.81  ? 407 SER C CB  1 
ATOM   9289  O OG  . SER C 1 407 ? 40.452  -23.384 4.407   1.00 31.95  ? 407 SER C OG  1 
ATOM   9290  N N   . ASP C 1 408 ? 37.930  -25.069 4.441   1.00 36.61  ? 408 ASP C N   1 
ATOM   9291  C CA  . ASP C 1 408 ? 37.715  -26.191 5.352   1.00 34.97  ? 408 ASP C CA  1 
ATOM   9292  C C   . ASP C 1 408 ? 38.964  -26.578 6.125   1.00 41.64  ? 408 ASP C C   1 
ATOM   9293  O O   . ASP C 1 408 ? 38.954  -27.613 6.800   1.00 40.34  ? 408 ASP C O   1 
ATOM   9294  C CB  . ASP C 1 408 ? 37.175  -27.437 4.631   1.00 43.87  ? 408 ASP C CB  1 
ATOM   9295  C CG  . ASP C 1 408 ? 37.557  -27.505 3.176   1.00 45.05  ? 408 ASP C CG  1 
ATOM   9296  O OD1 . ASP C 1 408 ? 38.749  -27.739 2.863   1.00 46.02  ? 408 ASP C OD1 1 
ATOM   9297  O OD2 . ASP C 1 408 ? 36.639  -27.358 2.345   1.00 36.62  ? 408 ASP C OD2 1 
ATOM   9298  N N   . LEU C 1 409 ? 40.031  -25.770 6.067   1.00 36.69  ? 409 LEU C N   1 
ATOM   9299  C CA  . LEU C 1 409 ? 41.195  -26.069 6.895   1.00 36.09  ? 409 LEU C CA  1 
ATOM   9300  C C   . LEU C 1 409 ? 40.822  -26.125 8.367   1.00 38.11  ? 409 LEU C C   1 
ATOM   9301  O O   . LEU C 1 409 ? 41.373  -26.926 9.129   1.00 46.26  ? 409 LEU C O   1 
ATOM   9302  C CB  . LEU C 1 409 ? 42.294  -25.042 6.673   1.00 28.69  ? 409 LEU C CB  1 
ATOM   9303  C CG  . LEU C 1 409 ? 43.419  -25.564 5.810   1.00 33.41  ? 409 LEU C CG  1 
ATOM   9304  C CD1 . LEU C 1 409 ? 44.541  -24.517 5.732   1.00 29.04  ? 409 LEU C CD1 1 
ATOM   9305  C CD2 . LEU C 1 409 ? 43.906  -26.885 6.400   1.00 31.54  ? 409 LEU C CD2 1 
ATOM   9306  N N   . GLY C 1 410 ? 39.910  -25.272 8.795   1.00 35.47  ? 410 GLY C N   1 
ATOM   9307  C CA  . GLY C 1 410 ? 39.334  -25.435 10.099  1.00 40.39  ? 410 GLY C CA  1 
ATOM   9308  C C   . GLY C 1 410 ? 37.835  -25.385 9.973   1.00 45.53  ? 410 GLY C C   1 
ATOM   9309  O O   . GLY C 1 410 ? 37.241  -25.744 8.952   1.00 45.29  ? 410 GLY C O   1 
ATOM   9310  N N   . PRO C 1 411 ? 37.209  -24.931 10.978  1.00 54.02  ? 411 PRO C N   1 
ATOM   9311  C CA  . PRO C 1 411 ? 35.933  -24.275 10.741  1.00 44.92  ? 411 PRO C CA  1 
ATOM   9312  C C   . PRO C 1 411 ? 36.200  -22.906 10.130  1.00 39.03  ? 411 PRO C C   1 
ATOM   9313  O O   . PRO C 1 411 ? 36.278  -21.934 10.886  1.00 49.18  ? 411 PRO C O   1 
ATOM   9314  C CB  . PRO C 1 411 ? 35.306  -24.183 12.144  1.00 40.70  ? 411 PRO C CB  1 
ATOM   9315  C CG  . PRO C 1 411 ? 36.182  -24.956 13.059  1.00 42.63  ? 411 PRO C CG  1 
ATOM   9316  C CD  . PRO C 1 411 ? 37.530  -25.050 12.409  1.00 50.59  ? 411 PRO C CD  1 
ATOM   9317  N N   . GLY C 1 412 ? 36.405  -22.789 8.810   1.00 34.64  ? 412 GLY C N   1 
ATOM   9318  C CA  . GLY C 1 412 ? 36.122  -21.493 8.188   1.00 36.35  ? 412 GLY C CA  1 
ATOM   9319  C C   . GLY C 1 412 ? 37.146  -20.579 7.508   1.00 31.55  ? 412 GLY C C   1 
ATOM   9320  O O   . GLY C 1 412 ? 37.711  -20.911 6.459   1.00 27.14  ? 412 GLY C O   1 
ATOM   9321  N N   . ALA C 1 413 ? 37.313  -19.368 8.030   1.00 26.99  ? 413 ALA C N   1 
ATOM   9322  C CA  . ALA C 1 413 ? 38.099  -18.349 7.350   1.00 27.26  ? 413 ALA C CA  1 
ATOM   9323  C C   . ALA C 1 413 ? 39.490  -18.300 7.956   1.00 27.56  ? 413 ALA C C   1 
ATOM   9324  O O   . ALA C 1 413 ? 39.642  -18.338 9.181   1.00 24.86  ? 413 ALA C O   1 
ATOM   9325  C CB  . ALA C 1 413 ? 37.449  -16.972 7.449   1.00 29.09  ? 413 ALA C CB  1 
ATOM   9326  N N   . GLU C 1 414 ? 40.499  -18.176 7.095   1.00 26.19  ? 414 GLU C N   1 
ATOM   9327  C CA  . GLU C 1 414 ? 41.889  -18.364 7.502   1.00 26.91  ? 414 GLU C CA  1 
ATOM   9328  C C   . GLU C 1 414 ? 42.612  -17.025 7.450   1.00 21.51  ? 414 GLU C C   1 
ATOM   9329  O O   . GLU C 1 414 ? 42.701  -16.399 6.389   1.00 28.13  ? 414 GLU C O   1 
ATOM   9330  C CB  . GLU C 1 414 ? 42.589  -19.417 6.640   1.00 21.01  ? 414 GLU C CB  1 
ATOM   9331  C CG  . GLU C 1 414 ? 43.957  -19.824 7.232   1.00 24.14  ? 414 GLU C CG  1 
ATOM   9332  C CD  . GLU C 1 414 ? 44.814  -20.686 6.294   1.00 30.65  ? 414 GLU C CD  1 
ATOM   9333  O OE1 . GLU C 1 414 ? 44.527  -20.714 5.069   1.00 25.42  ? 414 GLU C OE1 1 
ATOM   9334  O OE2 . GLU C 1 414 ? 45.789  -21.319 6.789   1.00 27.81  ? 414 GLU C OE2 1 
ATOM   9335  N N   . LEU C 1 415 ? 43.080  -16.574 8.610   1.00 24.66  ? 415 LEU C N   1 
ATOM   9336  C CA  . LEU C 1 415 ? 43.803  -15.325 8.784   1.00 23.62  ? 415 LEU C CA  1 
ATOM   9337  C C   . LEU C 1 415 ? 45.212  -15.631 9.290   1.00 25.73  ? 415 LEU C C   1 
ATOM   9338  O O   . LEU C 1 415 ? 45.427  -16.602 10.022  1.00 26.83  ? 415 LEU C O   1 
ATOM   9339  C CB  . LEU C 1 415 ? 43.082  -14.394 9.788   1.00 20.66  ? 415 LEU C CB  1 
ATOM   9340  C CG  . LEU C 1 415 ? 41.737  -13.753 9.416   1.00 23.88  ? 415 LEU C CG  1 
ATOM   9341  C CD1 . LEU C 1 415 ? 41.496  -12.537 10.255  1.00 24.22  ? 415 LEU C CD1 1 
ATOM   9342  C CD2 . LEU C 1 415 ? 41.706  -13.374 7.948   1.00 25.21  ? 415 LEU C CD2 1 
ATOM   9343  N N   . LEU C 1 416 ? 46.169  -14.801 8.880   1.00 23.67  ? 416 LEU C N   1 
ATOM   9344  C CA  . LEU C 1 416 ? 47.550  -14.865 9.341   1.00 22.67  ? 416 LEU C CA  1 
ATOM   9345  C C   . LEU C 1 416 ? 47.926  -13.504 9.912   1.00 22.57  ? 416 LEU C C   1 
ATOM   9346  O O   . LEU C 1 416 ? 47.739  -12.485 9.246   1.00 26.27  ? 416 LEU C O   1 
ATOM   9347  C CB  . LEU C 1 416 ? 48.489  -15.249 8.191   1.00 24.38  ? 416 LEU C CB  1 
ATOM   9348  C CG  . LEU C 1 416 ? 49.980  -15.331 8.540   1.00 29.20  ? 416 LEU C CG  1 
ATOM   9349  C CD1 . LEU C 1 416 ? 50.190  -16.228 9.766   1.00 22.46  ? 416 LEU C CD1 1 
ATOM   9350  C CD2 . LEU C 1 416 ? 50.803  -15.838 7.352   1.00 22.68  ? 416 LEU C CD2 1 
ATOM   9351  N N   . VAL C 1 417 ? 48.489  -13.487 11.117  1.00 26.20  ? 417 VAL C N   1 
ATOM   9352  C CA  . VAL C 1 417 ? 48.677  -12.269 11.904  1.00 22.08  ? 417 VAL C CA  1 
ATOM   9353  C C   . VAL C 1 417 ? 50.150  -12.115 12.271  1.00 25.15  ? 417 VAL C C   1 
ATOM   9354  O O   . VAL C 1 417 ? 50.779  -13.074 12.737  1.00 23.59  ? 417 VAL C O   1 
ATOM   9355  C CB  . VAL C 1 417 ? 47.811  -12.321 13.182  1.00 19.45  ? 417 VAL C CB  1 
ATOM   9356  C CG1 . VAL C 1 417 ? 47.709  -10.948 13.825  1.00 27.10  ? 417 VAL C CG1 1 
ATOM   9357  C CG2 . VAL C 1 417 ? 46.437  -12.844 12.840  1.00 25.51  ? 417 VAL C CG2 1 
ATOM   9358  N N   . PHE C 1 418 ? 50.675  -10.892 12.125  1.00 21.38  ? 418 PHE C N   1 
ATOM   9359  C CA  . PHE C 1 418 ? 52.086  -10.575 12.350  1.00 27.93  ? 418 PHE C CA  1 
ATOM   9360  C C   . PHE C 1 418 ? 52.275  -9.543  13.457  1.00 26.94  ? 418 PHE C C   1 
ATOM   9361  O O   . PHE C 1 418 ? 51.571  -8.526  13.510  1.00 27.36  ? 418 PHE C O   1 
ATOM   9362  C CB  . PHE C 1 418 ? 52.748  -10.021 11.070  1.00 28.44  ? 418 PHE C CB  1 
ATOM   9363  C CG  . PHE C 1 418 ? 52.887  -11.030 9.981   1.00 30.48  ? 418 PHE C CG  1 
ATOM   9364  C CD1 . PHE C 1 418 ? 53.879  -11.998 10.048  1.00 23.43  ? 418 PHE C CD1 1 
ATOM   9365  C CD2 . PHE C 1 418 ? 52.015  -11.031 8.903   1.00 23.39  ? 418 PHE C CD2 1 
ATOM   9366  C CE1 . PHE C 1 418 ? 54.011  -12.942 9.043   1.00 24.22  ? 418 PHE C CE1 1 
ATOM   9367  C CE2 . PHE C 1 418 ? 52.137  -11.972 7.909   1.00 24.49  ? 418 PHE C CE2 1 
ATOM   9368  C CZ  . PHE C 1 418 ? 53.149  -12.939 7.981   1.00 23.19  ? 418 PHE C CZ  1 
ATOM   9369  N N   . SER C 1 419 ? 53.268  -9.774  14.308  1.00 28.07  ? 419 SER C N   1 
ATOM   9370  C CA  . SER C 1 419 ? 53.670  -8.751  15.258  1.00 29.50  ? 419 SER C CA  1 
ATOM   9371  C C   . SER C 1 419 ? 55.142  -8.922  15.601  1.00 36.02  ? 419 SER C C   1 
ATOM   9372  O O   . SER C 1 419 ? 55.691  -10.034 15.541  1.00 30.86  ? 419 SER C O   1 
ATOM   9373  C CB  . SER C 1 419 ? 52.834  -8.784  16.547  1.00 32.91  ? 419 SER C CB  1 
ATOM   9374  O OG  . SER C 1 419 ? 53.172  -7.674  17.379  1.00 31.67  ? 419 SER C OG  1 
ATOM   9375  N N   . LYS C 1 420 ? 55.775  -7.793  15.953  1.00 30.41  ? 420 LYS C N   1 
ATOM   9376  C CA  . LYS C 1 420 ? 57.093  -7.808  16.568  1.00 30.64  ? 420 LYS C CA  1 
ATOM   9377  C C   . LYS C 1 420 ? 57.022  -8.219  18.025  1.00 32.81  ? 420 LYS C C   1 
ATOM   9378  O O   . LYS C 1 420 ? 58.056  -8.542  18.615  1.00 35.83  ? 420 LYS C O   1 
ATOM   9379  C CB  . LYS C 1 420 ? 57.759  -6.427  16.446  1.00 28.77  ? 420 LYS C CB  1 
ATOM   9380  C CG  . LYS C 1 420 ? 58.270  -6.115  15.036  1.00 35.66  ? 420 LYS C CG  1 
ATOM   9381  C CD  . LYS C 1 420 ? 59.249  -4.927  14.973  1.00 38.37  ? 420 LYS C CD  1 
ATOM   9382  C CE  . LYS C 1 420 ? 60.285  -5.073  13.829  1.00 42.94  ? 420 LYS C CE  1 
ATOM   9383  N NZ  . LYS C 1 420 ? 59.865  -5.956  12.676  1.00 36.63  ? 420 LYS C NZ  1 
ATOM   9384  N N   . ASP C 1 421 ? 55.825  -8.241  18.602  1.00 31.68  ? 421 ASP C N   1 
ATOM   9385  C CA  . ASP C 1 421 ? 55.636  -8.506  20.016  1.00 36.45  ? 421 ASP C CA  1 
ATOM   9386  C C   . ASP C 1 421 ? 54.595  -9.604  20.190  1.00 34.64  ? 421 ASP C C   1 
ATOM   9387  O O   . ASP C 1 421 ? 53.511  -9.537  19.603  1.00 34.05  ? 421 ASP C O   1 
ATOM   9388  C CB  . ASP C 1 421 ? 55.214  -7.219  20.728  1.00 38.42  ? 421 ASP C CB  1 
ATOM   9389  C CG  . ASP C 1 421 ? 55.093  -7.397  22.200  1.00 40.09  ? 421 ASP C CG  1 
ATOM   9390  O OD1 . ASP C 1 421 ? 54.059  -7.943  22.626  1.00 43.99  ? 421 ASP C OD1 1 
ATOM   9391  O OD2 . ASP C 1 421 ? 56.032  -7.008  22.924  1.00 45.98  ? 421 ASP C OD2 1 
ATOM   9392  N N   . TRP C 1 422 ? 54.925  -10.627 20.980  1.00 40.88  ? 422 TRP C N   1 
ATOM   9393  C CA  . TRP C 1 422 ? 53.998  -11.747 21.148  1.00 38.88  ? 422 TRP C CA  1 
ATOM   9394  C C   . TRP C 1 422 ? 52.695  -11.280 21.798  1.00 41.33  ? 422 TRP C C   1 
ATOM   9395  O O   . TRP C 1 422 ? 51.606  -11.440 21.232  1.00 40.82  ? 422 TRP C O   1 
ATOM   9396  C CB  . TRP C 1 422 ? 54.655  -12.870 21.958  1.00 36.57  ? 422 TRP C CB  1 
ATOM   9397  C CG  . TRP C 1 422 ? 53.736  -14.055 22.256  1.00 46.61  ? 422 TRP C CG  1 
ATOM   9398  C CD1 . TRP C 1 422 ? 53.344  -14.506 23.489  1.00 48.79  ? 422 TRP C CD1 1 
ATOM   9399  C CD2 . TRP C 1 422 ? 53.111  -14.919 21.301  1.00 41.18  ? 422 TRP C CD2 1 
ATOM   9400  N NE1 . TRP C 1 422 ? 52.504  -15.587 23.352  1.00 46.66  ? 422 TRP C NE1 1 
ATOM   9401  C CE2 . TRP C 1 422 ? 52.351  -15.859 22.017  1.00 48.17  ? 422 TRP C CE2 1 
ATOM   9402  C CE3 . TRP C 1 422 ? 53.111  -14.979 19.902  1.00 48.88  ? 422 TRP C CE3 1 
ATOM   9403  C CZ2 . TRP C 1 422 ? 51.605  -16.857 21.380  1.00 57.39  ? 422 TRP C CZ2 1 
ATOM   9404  C CZ3 . TRP C 1 422 ? 52.370  -15.971 19.270  1.00 47.53  ? 422 TRP C CZ3 1 
ATOM   9405  C CH2 . TRP C 1 422 ? 51.627  -16.892 20.008  1.00 48.77  ? 422 TRP C CH2 1 
ATOM   9406  N N   . ASP C 1 423 ? 52.791  -10.660 22.974  1.00 37.27  ? 423 ASP C N   1 
ATOM   9407  C CA  . ASP C 1 423 ? 51.579  -10.263 23.683  1.00 40.24  ? 423 ASP C CA  1 
ATOM   9408  C C   . ASP C 1 423 ? 50.751  -9.282  22.869  1.00 38.33  ? 423 ASP C C   1 
ATOM   9409  O O   . ASP C 1 423 ? 49.518  -9.249  22.993  1.00 36.59  ? 423 ASP C O   1 
ATOM   9410  C CB  . ASP C 1 423 ? 51.942  -9.667  25.040  1.00 41.68  ? 423 ASP C CB  1 
ATOM   9411  C CG  . ASP C 1 423 ? 52.154  -10.729 26.099  1.00 41.78  ? 423 ASP C CG  1 
ATOM   9412  O OD1 . ASP C 1 423 ? 51.266  -11.596 26.264  1.00 47.01  ? 423 ASP C OD1 1 
ATOM   9413  O OD2 . ASP C 1 423 ? 53.200  -10.683 26.771  1.00 44.20  ? 423 ASP C OD2 1 
ATOM   9414  N N   . ARG C 1 424 ? 51.410  -8.479  22.039  1.00 31.61  ? 424 ARG C N   1 
ATOM   9415  C CA  . ARG C 1 424 ? 50.698  -7.671  21.059  1.00 36.92  ? 424 ARG C CA  1 
ATOM   9416  C C   . ARG C 1 424 ? 50.007  -8.556  20.028  1.00 39.81  ? 424 ARG C C   1 
ATOM   9417  O O   . ARG C 1 424 ? 48.865  -8.286  19.631  1.00 38.10  ? 424 ARG C O   1 
ATOM   9418  C CB  . ARG C 1 424 ? 51.682  -6.714  20.383  1.00 36.33  ? 424 ARG C CB  1 
ATOM   9419  C CG  . ARG C 1 424 ? 51.110  -5.386  19.966  1.00 39.86  ? 424 ARG C CG  1 
ATOM   9420  C CD  . ARG C 1 424 ? 51.995  -4.247  20.463  1.00 48.74  ? 424 ARG C CD  1 
ATOM   9421  N NE  . ARG C 1 424 ? 53.390  -4.404  20.061  1.00 46.39  ? 424 ARG C NE  1 
ATOM   9422  C CZ  . ARG C 1 424 ? 53.864  -4.082  18.864  1.00 47.00  ? 424 ARG C CZ  1 
ATOM   9423  N NH1 . ARG C 1 424 ? 53.076  -3.600  17.920  1.00 48.94  ? 424 ARG C NH1 1 
ATOM   9424  N NH2 . ARG C 1 424 ? 55.163  -4.236  18.613  1.00 40.15  ? 424 ARG C NH2 1 
ATOM   9425  N N   . LEU C 1 425 ? 50.694  -9.615  19.575  1.00 37.50  ? 425 LEU C N   1 
ATOM   9426  C CA  . LEU C 1 425 ? 50.086  -10.551 18.638  1.00 34.32  ? 425 LEU C CA  1 
ATOM   9427  C C   . LEU C 1 425 ? 48.883  -11.233 19.262  1.00 34.94  ? 425 LEU C C   1 
ATOM   9428  O O   . LEU C 1 425 ? 47.842  -11.401 18.613  1.00 36.69  ? 425 LEU C O   1 
ATOM   9429  C CB  . LEU C 1 425 ? 51.124  -11.585 18.192  1.00 38.64  ? 425 LEU C CB  1 
ATOM   9430  C CG  . LEU C 1 425 ? 50.693  -12.703 17.240  1.00 35.40  ? 425 LEU C CG  1 
ATOM   9431  C CD1 . LEU C 1 425 ? 49.881  -12.165 16.127  1.00 27.51  ? 425 LEU C CD1 1 
ATOM   9432  C CD2 . LEU C 1 425 ? 51.917  -13.421 16.678  1.00 38.31  ? 425 LEU C CD2 1 
ATOM   9433  N N   . THR C 1 426 ? 49.001  -11.625 20.527  1.00 33.29  ? 426 THR C N   1 
ATOM   9434  C CA  . THR C 1 426 ? 47.868  -12.236 21.208  1.00 38.65  ? 426 THR C CA  1 
ATOM   9435  C C   . THR C 1 426 ? 46.714  -11.247 21.340  1.00 38.45  ? 426 THR C C   1 
ATOM   9436  O O   . THR C 1 426 ? 45.547  -11.625 21.186  1.00 34.54  ? 426 THR C O   1 
ATOM   9437  C CB  . THR C 1 426 ? 48.313  -12.772 22.573  1.00 36.98  ? 426 THR C CB  1 
ATOM   9438  O OG1 . THR C 1 426 ? 49.234  -13.848 22.368  1.00 46.30  ? 426 THR C OG1 1 
ATOM   9439  C CG2 . THR C 1 426 ? 47.129  -13.285 23.388  1.00 36.57  ? 426 THR C CG2 1 
ATOM   9440  N N   . ALA C 1 427 ? 47.021  -9.967  21.594  1.00 33.68  ? 427 ALA C N   1 
ATOM   9441  C CA  . ALA C 1 427 ? 45.951  -8.984  21.726  1.00 36.56  ? 427 ALA C CA  1 
ATOM   9442  C C   . ALA C 1 427 ? 45.260  -8.761  20.390  1.00 35.46  ? 427 ALA C C   1 
ATOM   9443  O O   . ALA C 1 427 ? 44.026  -8.728  20.318  1.00 32.00  ? 427 ALA C O   1 
ATOM   9444  C CB  . ALA C 1 427 ? 46.502  -7.668  22.282  1.00 31.73  ? 427 ALA C CB  1 
ATOM   9445  N N   . MET C 1 428 ? 46.048  -8.606  19.324  1.00 34.02  ? 428 MET C N   1 
ATOM   9446  C CA  . MET C 1 428 ? 45.489  -8.512  17.986  1.00 33.18  ? 428 MET C CA  1 
ATOM   9447  C C   . MET C 1 428 ? 44.560  -9.682  17.693  1.00 35.45  ? 428 MET C C   1 
ATOM   9448  O O   . MET C 1 428 ? 43.475  -9.500  17.125  1.00 31.46  ? 428 MET C O   1 
ATOM   9449  C CB  . MET C 1 428 ? 46.616  -8.478  16.961  1.00 34.79  ? 428 MET C CB  1 
ATOM   9450  C CG  . MET C 1 428 ? 47.255  -7.137  16.752  1.00 35.22  ? 428 MET C CG  1 
ATOM   9451  S SD  . MET C 1 428 ? 48.448  -7.312  15.407  1.00 37.72  ? 428 MET C SD  1 
ATOM   9452  C CE  . MET C 1 428 ? 49.925  -6.840  16.280  1.00 39.50  ? 428 MET C CE  1 
ATOM   9453  N N   . LYS C 1 429 ? 44.971  -10.893 18.081  1.00 34.64  ? 429 LYS C N   1 
ATOM   9454  C CA  . LYS C 1 429 ? 44.182  -12.077 17.760  1.00 35.24  ? 429 LYS C CA  1 
ATOM   9455  C C   . LYS C 1 429 ? 42.818  -12.013 18.427  1.00 36.79  ? 429 LYS C C   1 
ATOM   9456  O O   . LYS C 1 429 ? 41.814  -12.453 17.850  1.00 36.18  ? 429 LYS C O   1 
ATOM   9457  C CB  . LYS C 1 429 ? 44.935  -13.342 18.184  1.00 37.49  ? 429 LYS C CB  1 
ATOM   9458  C CG  . LYS C 1 429 ? 46.042  -13.779 17.225  1.00 34.73  ? 429 LYS C CG  1 
ATOM   9459  C CD  . LYS C 1 429 ? 46.155  -15.302 17.196  1.00 40.85  ? 429 LYS C CD  1 
ATOM   9460  C CE  . LYS C 1 429 ? 46.793  -15.830 18.483  1.00 40.77  ? 429 LYS C CE  1 
ATOM   9461  N NZ  . LYS C 1 429 ? 46.880  -17.318 18.508  1.00 43.94  ? 429 LYS C NZ  1 
ATOM   9462  N N   . ASP C 1 430 ? 42.759  -11.454 19.639  1.00 38.14  ? 430 ASP C N   1 
ATOM   9463  C CA  . ASP C 1 430 ? 41.483  -11.355 20.342  1.00 41.46  ? 430 ASP C CA  1 
ATOM   9464  C C   . ASP C 1 430 ? 40.594  -10.258 19.769  1.00 33.87  ? 430 ASP C C   1 
ATOM   9465  O O   . ASP C 1 430 ? 39.367  -10.396 19.798  1.00 36.84  ? 430 ASP C O   1 
ATOM   9466  C CB  . ASP C 1 430 ? 41.717  -11.134 21.838  1.00 43.41  ? 430 ASP C CB  1 
ATOM   9467  C CG  . ASP C 1 430 ? 42.411  -12.316 22.494  1.00 49.67  ? 430 ASP C CG  1 
ATOM   9468  O OD1 . ASP C 1 430 ? 42.332  -13.432 21.938  1.00 51.04  ? 430 ASP C OD1 1 
ATOM   9469  O OD2 . ASP C 1 430 ? 43.038  -12.131 23.561  1.00 56.95  ? 430 ASP C OD2 1 
ATOM   9470  N N   . GLU C 1 431 ? 41.173  -9.178  19.229  1.00 36.77  ? 431 GLU C N   1 
ATOM   9471  C CA  . GLU C 1 431 ? 40.333  -8.192  18.550  1.00 34.69  ? 431 GLU C CA  1 
ATOM   9472  C C   . GLU C 1 431 ? 39.705  -8.780  17.291  1.00 34.33  ? 431 GLU C C   1 
ATOM   9473  O O   . GLU C 1 431 ? 38.581  -8.401  16.938  1.00 36.21  ? 431 GLU C O   1 
ATOM   9474  C CB  . GLU C 1 431 ? 41.116  -6.917  18.222  1.00 34.21  ? 431 GLU C CB  1 
ATOM   9475  C CG  . GLU C 1 431 ? 41.407  -5.997  19.425  1.00 34.52  ? 431 GLU C CG  1 
ATOM   9476  C CD  . GLU C 1 431 ? 40.262  -5.022  19.747  1.00 46.26  ? 431 GLU C CD  1 
ATOM   9477  O OE1 . GLU C 1 431 ? 39.285  -5.428  20.431  1.00 44.22  ? 431 GLU C OE1 1 
ATOM   9478  O OE2 . GLU C 1 431 ? 40.344  -3.838  19.332  1.00 49.17  ? 431 GLU C OE2 1 
ATOM   9479  N N   . ILE C 1 432 ? 40.374  -9.741  16.640  1.00 28.50  ? 432 ILE C N   1 
ATOM   9480  C CA  . ILE C 1 432 ? 39.794  -10.381 15.455  1.00 33.10  ? 432 ILE C CA  1 
ATOM   9481  C C   . ILE C 1 432 ? 38.588  -11.234 15.838  1.00 36.13  ? 432 ILE C C   1 
ATOM   9482  O O   . ILE C 1 432 ? 37.558  -11.225 15.151  1.00 41.22  ? 432 ILE C O   1 
ATOM   9483  C CB  . ILE C 1 432 ? 40.841  -11.221 14.695  1.00 26.77  ? 432 ILE C CB  1 
ATOM   9484  C CG1 . ILE C 1 432 ? 41.974  -10.352 14.146  1.00 33.85  ? 432 ILE C CG1 1 
ATOM   9485  C CG2 . ILE C 1 432 ? 40.186  -11.960 13.537  1.00 30.78  ? 432 ILE C CG2 1 
ATOM   9486  C CD1 . ILE C 1 432 ? 43.085  -11.161 13.455  1.00 26.17  ? 432 ILE C CD1 1 
ATOM   9487  N N   . ALA C 1 433 ? 38.702  -12.000 16.922  1.00 34.46  ? 433 ALA C N   1 
ATOM   9488  C CA  . ALA C 1 433 ? 37.562  -12.749 17.435  1.00 33.35  ? 433 ALA C CA  1 
ATOM   9489  C C   . ALA C 1 433 ? 36.394  -11.822 17.745  1.00 37.77  ? 433 ALA C C   1 
ATOM   9490  O O   . ALA C 1 433 ? 35.272  -12.030 17.274  1.00 37.30  ? 433 ALA C O   1 
ATOM   9491  C CB  . ALA C 1 433 ? 37.979  -13.520 18.687  1.00 35.36  ? 433 ALA C CB  1 
ATOM   9492  N N   . THR C 1 434 ? 36.645  -10.789 18.543  1.00 35.57  ? 434 THR C N   1 
ATOM   9493  C CA  . THR C 1 434 ? 35.594  -9.837  18.872  1.00 40.12  ? 434 THR C CA  1 
ATOM   9494  C C   . THR C 1 434 ? 34.973  -9.233  17.618  1.00 39.59  ? 434 THR C C   1 
ATOM   9495  O O   . THR C 1 434 ? 33.754  -9.034  17.549  1.00 44.12  ? 434 THR C O   1 
ATOM   9496  C CB  . THR C 1 434 ? 36.176  -8.747  19.766  1.00 36.82  ? 434 THR C CB  1 
ATOM   9497  O OG1 . THR C 1 434 ? 36.657  -9.348  20.973  1.00 37.79  ? 434 THR C OG1 1 
ATOM   9498  C CG2 . THR C 1 434 ? 35.129  -7.708  20.097  1.00 43.93  ? 434 THR C CG2 1 
ATOM   9499  N N   . THR C 1 435 ? 35.789  -8.954  16.607  1.00 41.26  ? 435 THR C N   1 
ATOM   9500  C CA  . THR C 1 435 ? 35.333  -8.160  15.477  1.00 38.54  ? 435 THR C CA  1 
ATOM   9501  C C   . THR C 1 435 ? 34.843  -9.001  14.307  1.00 41.52  ? 435 THR C C   1 
ATOM   9502  O O   . THR C 1 435 ? 33.900  -8.601  13.611  1.00 43.35  ? 435 THR C O   1 
ATOM   9503  C CB  . THR C 1 435 ? 36.463  -7.251  15.020  1.00 41.25  ? 435 THR C CB  1 
ATOM   9504  O OG1 . THR C 1 435 ? 37.212  -6.848  16.171  1.00 49.54  ? 435 THR C OG1 1 
ATOM   9505  C CG2 . THR C 1 435 ? 35.913  -6.025  14.347  1.00 40.29  ? 435 THR C CG2 1 
ATOM   9506  N N   . ALA C 1 436 ? 35.475  -10.144 14.047  1.00 37.94  ? 436 ALA C N   1 
ATOM   9507  C CA  . ALA C 1 436 ? 35.030  -11.009 12.963  1.00 37.34  ? 436 ALA C CA  1 
ATOM   9508  C C   . ALA C 1 436 ? 34.285  -12.240 13.445  1.00 40.34  ? 436 ALA C C   1 
ATOM   9509  O O   . ALA C 1 436 ? 33.570  -12.857 12.649  1.00 43.74  ? 436 ALA C O   1 
ATOM   9510  C CB  . ALA C 1 436 ? 36.222  -11.450 12.102  1.00 33.20  ? 436 ALA C CB  1 
ATOM   9511  N N   . GLY C 1 437 ? 34.413  -12.593 14.723  1.00 37.51  ? 437 GLY C N   1 
ATOM   9512  C CA  . GLY C 1 437 ? 33.808  -13.796 15.257  1.00 40.98  ? 437 GLY C CA  1 
ATOM   9513  C C   . GLY C 1 437 ? 34.631  -15.035 14.974  1.00 40.20  ? 437 GLY C C   1 
ATOM   9514  O O   . GLY C 1 437 ? 35.388  -15.057 13.998  1.00 35.19  ? 437 GLY C O   1 
ATOM   9515  N N   . THR C 1 438 ? 34.490  -16.063 15.821  1.00 42.05  ? 438 THR C N   1 
ATOM   9516  C CA  . THR C 1 438 ? 35.030  -17.398 15.586  1.00 41.46  ? 438 THR C CA  1 
ATOM   9517  C C   . THR C 1 438 ? 33.927  -18.439 15.766  1.00 44.56  ? 438 THR C C   1 
ATOM   9518  O O   . THR C 1 438 ? 32.800  -18.125 16.169  1.00 42.20  ? 438 THR C O   1 
ATOM   9519  C CB  . THR C 1 438 ? 36.194  -17.725 16.534  1.00 42.15  ? 438 THR C CB  1 
ATOM   9520  O OG1 . THR C 1 438 ? 35.712  -17.771 17.884  1.00 46.70  ? 438 THR C OG1 1 
ATOM   9521  C CG2 . THR C 1 438 ? 37.321  -16.687 16.414  1.00 38.82  ? 438 THR C CG2 1 
ATOM   9522  N N   . LEU C 1 439 ? 34.272  -19.694 15.457  1.00 42.88  ? 439 LEU C N   1 
ATOM   9523  C CA  . LEU C 1 439 ? 33.444  -20.869 15.711  1.00 42.93  ? 439 LEU C CA  1 
ATOM   9524  C C   . LEU C 1 439 ? 34.084  -21.748 16.785  1.00 46.70  ? 439 LEU C C   1 
ATOM   9525  O O   . LEU C 1 439 ? 35.311  -21.836 16.879  1.00 51.08  ? 439 LEU C O   1 
ATOM   9526  C CB  . LEU C 1 439 ? 33.224  -21.670 14.421  1.00 43.54  ? 439 LEU C CB  1 
ATOM   9527  C CG  . LEU C 1 439 ? 32.873  -20.834 13.184  1.00 41.85  ? 439 LEU C CG  1 
ATOM   9528  C CD1 . LEU C 1 439 ? 33.355  -21.449 11.884  1.00 41.06  ? 439 LEU C CD1 1 
ATOM   9529  C CD2 . LEU C 1 439 ? 31.376  -20.644 13.119  1.00 39.07  ? 439 LEU C CD2 1 
ATOM   9530  N N   . SER C 1 440 ? 33.245  -22.406 17.595  1.00 55.68  ? 440 SER C N   1 
ATOM   9531  C CA  . SER C 1 440 ? 33.719  -23.153 18.777  1.00 46.89  ? 440 SER C CA  1 
ATOM   9532  C C   . SER C 1 440 ? 32.659  -23.962 19.550  1.00 51.69  ? 440 SER C C   1 
ATOM   9533  O O   . SER C 1 440 ? 31.557  -24.288 19.087  1.00 50.50  ? 440 SER C O   1 
ATOM   9534  C CB  . SER C 1 440 ? 34.369  -22.183 19.737  1.00 43.64  ? 440 SER C CB  1 
ATOM   9535  O OG  . SER C 1 440 ? 33.573  -21.026 19.791  1.00 45.83  ? 440 SER C OG  1 
ATOM   9536  N N   . MET D 1 1   ? 38.988  22.999  21.287  1.00 62.95  ? 1   MET D N   1 
ATOM   9537  C CA  . MET D 1 1   ? 37.834  23.693  20.717  1.00 64.68  ? 1   MET D CA  1 
ATOM   9538  C C   . MET D 1 1   ? 36.879  22.726  19.992  1.00 57.35  ? 1   MET D C   1 
ATOM   9539  O O   . MET D 1 1   ? 36.628  22.913  18.786  1.00 44.51  ? 1   MET D O   1 
ATOM   9540  C CB  . MET D 1 1   ? 38.304  24.793  19.747  1.00 62.99  ? 1   MET D CB  1 
ATOM   9541  C CG  . MET D 1 1   ? 38.338  26.201  20.348  1.00 69.35  ? 1   MET D CG  1 
ATOM   9542  S SD  . MET D 1 1   ? 38.846  27.506  19.200  1.00 94.96  ? 1   MET D SD  1 
ATOM   9543  C CE  . MET D 1 1   ? 37.821  27.150  17.768  1.00 75.65  ? 1   MET D CE  1 
ATOM   9544  N N   . PRO D 1 2   ? 36.341  21.717  20.700  1.00 53.19  ? 2   PRO D N   1 
ATOM   9545  C CA  . PRO D 1 2   ? 35.442  20.766  20.036  1.00 41.84  ? 2   PRO D CA  1 
ATOM   9546  C C   . PRO D 1 2   ? 34.120  21.440  19.694  1.00 40.88  ? 2   PRO D C   1 
ATOM   9547  O O   . PRO D 1 2   ? 33.727  22.451  20.287  1.00 35.15  ? 2   PRO D O   1 
ATOM   9548  C CB  . PRO D 1 2   ? 35.257  19.655  21.072  1.00 34.07  ? 2   PRO D CB  1 
ATOM   9549  C CG  . PRO D 1 2   ? 35.399  20.365  22.382  1.00 41.03  ? 2   PRO D CG  1 
ATOM   9550  C CD  . PRO D 1 2   ? 36.348  21.515  22.166  1.00 42.84  ? 2   PRO D CD  1 
ATOM   9551  N N   . LYS D 1 3   ? 33.430  20.872  18.711  1.00 33.50  ? 3   LYS D N   1 
ATOM   9552  C CA  . LYS D 1 3   ? 32.270  21.549  18.157  1.00 36.47  ? 3   LYS D CA  1 
ATOM   9553  C C   . LYS D 1 3   ? 31.162  20.529  17.906  1.00 35.39  ? 3   LYS D C   1 
ATOM   9554  O O   . LYS D 1 3   ? 31.421  19.331  17.764  1.00 36.44  ? 3   LYS D O   1 
ATOM   9555  C CB  . LYS D 1 3   ? 32.672  22.306  16.883  1.00 28.12  ? 3   LYS D CB  1 
ATOM   9556  C CG  . LYS D 1 3   ? 33.246  21.394  15.816  1.00 31.28  ? 3   LYS D CG  1 
ATOM   9557  C CD  . LYS D 1 3   ? 33.849  22.131  14.632  1.00 30.92  ? 3   LYS D CD  1 
ATOM   9558  C CE  . LYS D 1 3   ? 34.140  21.138  13.494  1.00 31.68  ? 3   LYS D CE  1 
ATOM   9559  N NZ  . LYS D 1 3   ? 35.329  20.280  13.795  1.00 28.56  ? 3   LYS D NZ  1 
ATOM   9560  N N   . ILE D 1 4   ? 29.917  21.013  17.897  1.00 31.15  ? 4   ILE D N   1 
ATOM   9561  C CA  . ILE D 1 4   ? 28.744  20.226  17.515  1.00 28.41  ? 4   ILE D CA  1 
ATOM   9562  C C   . ILE D 1 4   ? 28.441  20.521  16.047  1.00 27.37  ? 4   ILE D C   1 
ATOM   9563  O O   . ILE D 1 4   ? 27.996  21.626  15.706  1.00 29.68  ? 4   ILE D O   1 
ATOM   9564  C CB  . ILE D 1 4   ? 27.536  20.551  18.404  1.00 33.78  ? 4   ILE D CB  1 
ATOM   9565  C CG1 . ILE D 1 4   ? 27.896  20.441  19.877  1.00 34.80  ? 4   ILE D CG1 1 
ATOM   9566  C CG2 . ILE D 1 4   ? 26.345  19.668  18.080  1.00 31.47  ? 4   ILE D CG2 1 
ATOM   9567  C CD1 . ILE D 1 4   ? 27.014  21.293  20.733  1.00 37.79  ? 4   ILE D CD1 1 
ATOM   9568  N N   . ILE D 1 5   ? 28.688  19.548  15.169  1.00 30.10  ? 5   ILE D N   1 
ATOM   9569  C CA  . ILE D 1 5   ? 28.462  19.718  13.735  1.00 22.85  ? 5   ILE D CA  1 
ATOM   9570  C C   . ILE D 1 5   ? 26.981  19.504  13.450  1.00 28.62  ? 5   ILE D C   1 
ATOM   9571  O O   . ILE D 1 5   ? 26.451  18.407  13.653  1.00 28.45  ? 5   ILE D O   1 
ATOM   9572  C CB  . ILE D 1 5   ? 29.318  18.748  12.920  1.00 25.51  ? 5   ILE D CB  1 
ATOM   9573  C CG1 . ILE D 1 5   ? 30.781  18.829  13.342  1.00 27.35  ? 5   ILE D CG1 1 
ATOM   9574  C CG2 . ILE D 1 5   ? 29.127  18.998  11.425  1.00 24.99  ? 5   ILE D CG2 1 
ATOM   9575  C CD1 . ILE D 1 5   ? 31.510  17.542  13.110  1.00 27.39  ? 5   ILE D CD1 1 
ATOM   9576  N N   . LEU D 1 6   ? 26.313  20.544  12.955  1.00 28.94  ? 6   LEU D N   1 
ATOM   9577  C CA  . LEU D 1 6   ? 24.850  20.630  12.998  1.00 28.12  ? 6   LEU D CA  1 
ATOM   9578  C C   . LEU D 1 6   ? 24.291  20.871  11.598  1.00 29.82  ? 6   LEU D C   1 
ATOM   9579  O O   . LEU D 1 6   ? 24.051  22.021  11.201  1.00 31.12  ? 6   LEU D O   1 
ATOM   9580  C CB  . LEU D 1 6   ? 24.436  21.735  13.969  1.00 29.01  ? 6   LEU D CB  1 
ATOM   9581  C CG  . LEU D 1 6   ? 23.113  21.767  14.730  1.00 31.70  ? 6   LEU D CG  1 
ATOM   9582  C CD1 . LEU D 1 6   ? 22.110  22.677  14.000  1.00 31.60  ? 6   LEU D CD1 1 
ATOM   9583  C CD2 . LEU D 1 6   ? 22.572  20.375  14.935  1.00 28.46  ? 6   LEU D CD2 1 
ATOM   9584  N N   . PRO D 1 7   ? 24.055  19.815  10.823  1.00 26.88  ? 7   PRO D N   1 
ATOM   9585  C CA  . PRO D 1 7   ? 23.620  19.992  9.418   1.00 31.13  ? 7   PRO D CA  1 
ATOM   9586  C C   . PRO D 1 7   ? 22.121  20.250  9.295   1.00 35.32  ? 7   PRO D C   1 
ATOM   9587  O O   . PRO D 1 7   ? 21.370  19.460  8.725   1.00 33.81  ? 7   PRO D O   1 
ATOM   9588  C CB  . PRO D 1 7   ? 24.033  18.657  8.771   1.00 30.83  ? 7   PRO D CB  1 
ATOM   9589  C CG  . PRO D 1 7   ? 24.608  17.781  9.903   1.00 32.44  ? 7   PRO D CG  1 
ATOM   9590  C CD  . PRO D 1 7   ? 24.173  18.394  11.184  1.00 28.34  ? 7   PRO D CD  1 
ATOM   9591  N N   . ASN D 1 8   ? 21.674  21.384  9.831   1.00 33.14  ? 8   ASN D N   1 
ATOM   9592  C CA  . ASN D 1 8   ? 20.256  21.749  9.797   1.00 37.51  ? 8   ASN D CA  1 
ATOM   9593  C C   . ASN D 1 8   ? 19.898  22.375  8.444   1.00 39.30  ? 8   ASN D C   1 
ATOM   9594  O O   . ASN D 1 8   ? 19.557  23.550  8.335   1.00 40.94  ? 8   ASN D O   1 
ATOM   9595  C CB  . ASN D 1 8   ? 19.934  22.686  10.954  1.00 33.38  ? 8   ASN D CB  1 
ATOM   9596  C CG  . ASN D 1 8   ? 20.720  23.998  10.890  1.00 28.34  ? 8   ASN D CG  1 
ATOM   9597  O OD1 . ASN D 1 8   ? 21.861  24.034  10.441  1.00 25.16  ? 8   ASN D OD1 1 
ATOM   9598  N ND2 . ASN D 1 8   ? 20.099  25.081  11.340  1.00 31.81  ? 8   ASN D ND2 1 
ATOM   9599  N N   . PHE D 1 9   ? 19.945  21.549  7.397   1.00 42.85  ? 9   PHE D N   1 
ATOM   9600  C CA  . PHE D 1 9   ? 19.639  21.988  6.039   1.00 51.62  ? 9   PHE D CA  1 
ATOM   9601  C C   . PHE D 1 9   ? 18.845  20.912  5.304   1.00 58.81  ? 9   PHE D C   1 
ATOM   9602  O O   . PHE D 1 9   ? 18.695  19.788  5.787   1.00 61.80  ? 9   PHE D O   1 
ATOM   9603  C CB  . PHE D 1 9   ? 20.919  22.289  5.247   1.00 55.23  ? 9   PHE D CB  1 
ATOM   9604  C CG  . PHE D 1 9   ? 21.612  21.046  4.742   1.00 58.37  ? 9   PHE D CG  1 
ATOM   9605  C CD1 . PHE D 1 9   ? 22.136  20.120  5.633   1.00 52.87  ? 9   PHE D CD1 1 
ATOM   9606  C CD2 . PHE D 1 9   ? 21.716  20.792  3.383   1.00 62.84  ? 9   PHE D CD2 1 
ATOM   9607  C CE1 . PHE D 1 9   ? 22.742  18.964  5.176   1.00 50.87  ? 9   PHE D CE1 1 
ATOM   9608  C CE2 . PHE D 1 9   ? 22.331  19.639  2.922   1.00 58.23  ? 9   PHE D CE2 1 
ATOM   9609  C CZ  . PHE D 1 9   ? 22.845  18.725  3.820   1.00 54.86  ? 9   PHE D CZ  1 
ATOM   9610  N N   . ARG D 1 10  ? 18.325  21.286  4.121   1.00 67.53  ? 10  ARG D N   1 
ATOM   9611  C CA  . ARG D 1 10  ? 17.778  20.399  3.082   1.00 67.30  ? 10  ARG D CA  1 
ATOM   9612  C C   . ARG D 1 10  ? 16.332  19.960  3.326   1.00 65.76  ? 10  ARG D C   1 
ATOM   9613  O O   . ARG D 1 10  ? 16.083  18.829  3.762   1.00 61.63  ? 10  ARG D O   1 
ATOM   9614  C CB  . ARG D 1 10  ? 18.672  19.158  2.892   1.00 64.25  ? 10  ARG D CB  1 
ATOM   9615  C CG  . ARG D 1 10  ? 18.460  18.433  1.562   1.00 68.55  ? 10  ARG D CG  1 
ATOM   9616  C CD  . ARG D 1 10  ? 19.041  17.014  1.541   1.00 64.78  ? 10  ARG D CD  1 
ATOM   9617  N NE  . ARG D 1 10  ? 18.439  16.205  0.481   1.00 62.08  ? 10  ARG D NE  1 
ATOM   9618  C CZ  . ARG D 1 10  ? 18.765  16.274  -0.806  1.00 63.34  ? 10  ARG D CZ  1 
ATOM   9619  N NH1 . ARG D 1 10  ? 19.739  17.064  -1.233  1.00 69.19  ? 10  ARG D NH1 1 
ATOM   9620  N NH2 . ARG D 1 10  ? 18.093  15.534  -1.690  1.00 50.42  ? 10  ARG D NH2 1 
ATOM   9621  N N   . ALA D 1 11  ? 15.378  20.845  3.027   1.00 74.61  ? 11  ALA D N   1 
ATOM   9622  C CA  . ALA D 1 11  ? 13.937  20.519  2.964   1.00 78.41  ? 11  ALA D CA  1 
ATOM   9623  C C   . ALA D 1 11  ? 13.319  20.084  4.299   1.00 80.02  ? 11  ALA D C   1 
ATOM   9624  O O   . ALA D 1 11  ? 12.094  19.939  4.415   1.00 69.82  ? 11  ALA D O   1 
ATOM   9625  C CB  . ALA D 1 11  ? 13.687  19.434  1.899   1.00 72.26  ? 11  ALA D CB  1 
ATOM   9626  N N   . SER D 1 30  ? 16.939  5.054   5.989   1.00 53.03  ? 30  SER D N   1 
ATOM   9627  C CA  . SER D 1 30  ? 18.058  4.154   5.665   1.00 56.17  ? 30  SER D CA  1 
ATOM   9628  C C   . SER D 1 30  ? 19.206  4.833   4.852   1.00 55.11  ? 30  SER D C   1 
ATOM   9629  O O   . SER D 1 30  ? 20.346  4.343   4.814   1.00 58.86  ? 30  SER D O   1 
ATOM   9630  C CB  . SER D 1 30  ? 17.536  2.920   4.922   1.00 58.61  ? 30  SER D CB  1 
ATOM   9631  O OG  . SER D 1 30  ? 17.289  3.221   3.565   1.00 58.62  ? 30  SER D OG  1 
ATOM   9632  N N   . THR D 1 31  ? 18.909  5.955   4.196   1.00 52.99  ? 31  THR D N   1 
ATOM   9633  C CA  . THR D 1 31  ? 19.955  6.681   3.485   1.00 46.53  ? 31  THR D CA  1 
ATOM   9634  C C   . THR D 1 31  ? 20.851  7.431   4.467   1.00 45.32  ? 31  THR D C   1 
ATOM   9635  O O   . THR D 1 31  ? 20.451  7.749   5.591   1.00 48.01  ? 31  THR D O   1 
ATOM   9636  C CB  . THR D 1 31  ? 19.360  7.670   2.481   1.00 46.51  ? 31  THR D CB  1 
ATOM   9637  O OG1 . THR D 1 31  ? 18.514  8.598   3.170   1.00 50.36  ? 31  THR D OG1 1 
ATOM   9638  C CG2 . THR D 1 31  ? 18.557  6.936   1.401   1.00 46.43  ? 31  THR D CG2 1 
ATOM   9639  N N   . ASP D 1 32  ? 22.074  7.727   4.026   1.00 39.78  ? 32  ASP D N   1 
ATOM   9640  C CA  . ASP D 1 32  ? 23.068  8.387   4.870   1.00 40.69  ? 32  ASP D CA  1 
ATOM   9641  C C   . ASP D 1 32  ? 23.537  9.707   4.259   1.00 38.68  ? 32  ASP D C   1 
ATOM   9642  O O   . ASP D 1 32  ? 24.726  10.025  4.256   1.00 37.24  ? 32  ASP D O   1 
ATOM   9643  C CB  . ASP D 1 32  ? 24.252  7.455   5.167   1.00 41.38  ? 32  ASP D CB  1 
ATOM   9644  C CG  . ASP D 1 32  ? 25.044  7.046   3.917   1.00 36.99  ? 32  ASP D CG  1 
ATOM   9645  O OD1 . ASP D 1 32  ? 24.708  7.487   2.805   1.00 36.50  ? 32  ASP D OD1 1 
ATOM   9646  O OD2 . ASP D 1 32  ? 26.032  6.282   4.050   1.00 42.73  ? 32  ASP D OD2 1 
ATOM   9647  N N   . THR D 1 33  ? 22.589  10.506  3.758   1.00 41.20  ? 33  THR D N   1 
ATOM   9648  C CA  . THR D 1 33  ? 22.906  11.775  3.105   1.00 40.22  ? 33  THR D CA  1 
ATOM   9649  C C   . THR D 1 33  ? 23.726  12.689  3.997   1.00 35.00  ? 33  THR D C   1 
ATOM   9650  O O   . THR D 1 33  ? 24.449  13.553  3.494   1.00 35.59  ? 33  THR D O   1 
ATOM   9651  C CB  . THR D 1 33  ? 21.608  12.493  2.680   1.00 41.46  ? 33  THR D CB  1 
ATOM   9652  O OG1 . THR D 1 33  ? 20.597  11.528  2.357   1.00 45.07  ? 33  THR D OG1 1 
ATOM   9653  C CG2 . THR D 1 33  ? 21.834  13.358  1.470   1.00 39.25  ? 33  THR D CG2 1 
ATOM   9654  N N   . THR D 1 34  ? 23.659  12.490  5.302   1.00 36.58  ? 34  THR D N   1 
ATOM   9655  C CA  . THR D 1 34  ? 24.231  13.398  6.276   1.00 32.84  ? 34  THR D CA  1 
ATOM   9656  C C   . THR D 1 34  ? 25.560  12.903  6.833   1.00 34.71  ? 34  THR D C   1 
ATOM   9657  O O   . THR D 1 34  ? 26.300  13.686  7.444   1.00 29.18  ? 34  THR D O   1 
ATOM   9658  C CB  . THR D 1 34  ? 23.184  13.628  7.374   1.00 38.84  ? 34  THR D CB  1 
ATOM   9659  O OG1 . THR D 1 34  ? 22.246  14.610  6.908   1.00 46.74  ? 34  THR D OG1 1 
ATOM   9660  C CG2 . THR D 1 34  ? 23.780  14.120  8.657   1.00 45.51  ? 34  THR D CG2 1 
ATOM   9661  N N   . ALA D 1 35  ? 25.923  11.647  6.561   1.00 34.24  ? 35  ALA D N   1 
ATOM   9662  C CA  . ALA D 1 35  ? 27.192  11.129  7.060   1.00 35.28  ? 35  ALA D CA  1 
ATOM   9663  C C   . ALA D 1 35  ? 28.383  11.905  6.516   1.00 27.74  ? 35  ALA D C   1 
ATOM   9664  O O   . ALA D 1 35  ? 29.417  11.987  7.186   1.00 27.45  ? 35  ALA D O   1 
ATOM   9665  C CB  . ALA D 1 35  ? 27.331  9.648   6.711   1.00 31.41  ? 35  ALA D CB  1 
ATOM   9666  N N   . ARG D 1 36  ? 28.263  12.483  5.314   1.00 25.16  ? 36  ARG D N   1 
ATOM   9667  C CA  . ARG D 1 36  ? 29.391  13.204  4.718   1.00 25.37  ? 36  ARG D CA  1 
ATOM   9668  C C   . ARG D 1 36  ? 29.986  14.262  5.645   1.00 26.65  ? 36  ARG D C   1 
ATOM   9669  O O   . ARG D 1 36  ? 31.145  14.653  5.450   1.00 22.38  ? 36  ARG D O   1 
ATOM   9670  C CB  . ARG D 1 36  ? 28.970  13.869  3.407   1.00 26.12  ? 36  ARG D CB  1 
ATOM   9671  C CG  . ARG D 1 36  ? 28.152  15.168  3.620   1.00 26.74  ? 36  ARG D CG  1 
ATOM   9672  C CD  . ARG D 1 36  ? 27.140  15.351  2.518   1.00 27.19  ? 36  ARG D CD  1 
ATOM   9673  N NE  . ARG D 1 36  ? 27.791  15.477  1.225   1.00 26.47  ? 36  ARG D NE  1 
ATOM   9674  C CZ  . ARG D 1 36  ? 28.274  16.618  0.752   1.00 25.73  ? 36  ARG D CZ  1 
ATOM   9675  N NH1 . ARG D 1 36  ? 28.219  17.736  1.458   1.00 23.86  ? 36  ARG D NH1 1 
ATOM   9676  N NH2 . ARG D 1 36  ? 28.864  16.629  -0.440  1.00 22.11  ? 36  ARG D NH2 1 
ATOM   9677  N N   . PHE D 1 37  ? 29.229  14.748  6.635   1.00 22.81  ? 37  PHE D N   1 
ATOM   9678  C CA  . PHE D 1 37  ? 29.712  15.804  7.521   1.00 25.75  ? 37  PHE D CA  1 
ATOM   9679  C C   . PHE D 1 37  ? 30.596  15.288  8.655   1.00 27.76  ? 37  PHE D C   1 
ATOM   9680  O O   . PHE D 1 37  ? 31.100  16.094  9.444   1.00 26.14  ? 37  PHE D O   1 
ATOM   9681  C CB  . PHE D 1 37  ? 28.530  16.593  8.097   1.00 28.13  ? 37  PHE D CB  1 
ATOM   9682  C CG  . PHE D 1 37  ? 27.630  17.162  7.043   1.00 29.12  ? 37  PHE D CG  1 
ATOM   9683  C CD1 . PHE D 1 37  ? 28.107  18.121  6.169   1.00 28.69  ? 37  PHE D CD1 1 
ATOM   9684  C CD2 . PHE D 1 37  ? 26.327  16.724  6.897   1.00 32.14  ? 37  PHE D CD2 1 
ATOM   9685  C CE1 . PHE D 1 37  ? 27.310  18.634  5.168   1.00 29.96  ? 37  PHE D CE1 1 
ATOM   9686  C CE2 . PHE D 1 37  ? 25.512  17.245  5.896   1.00 29.88  ? 37  PHE D CE2 1 
ATOM   9687  C CZ  . PHE D 1 37  ? 26.011  18.198  5.038   1.00 32.48  ? 37  PHE D CZ  1 
ATOM   9688  N N   . LEU D 1 38  ? 30.805  13.976  8.752   1.00 28.91  ? 38  LEU D N   1 
ATOM   9689  C CA  . LEU D 1 38  ? 31.796  13.444  9.678   1.00 24.08  ? 38  LEU D CA  1 
ATOM   9690  C C   . LEU D 1 38  ? 33.194  13.931  9.342   1.00 23.89  ? 38  LEU D C   1 
ATOM   9691  O O   . LEU D 1 38  ? 34.038  14.054  10.231  1.00 24.90  ? 38  LEU D O   1 
ATOM   9692  C CB  . LEU D 1 38  ? 31.745  11.920  9.652   1.00 27.89  ? 38  LEU D CB  1 
ATOM   9693  C CG  . LEU D 1 38  ? 31.022  11.288  10.843  1.00 32.65  ? 38  LEU D CG  1 
ATOM   9694  C CD1 . LEU D 1 38  ? 31.060  9.763   10.788  1.00 35.49  ? 38  LEU D CD1 1 
ATOM   9695  C CD2 . LEU D 1 38  ? 31.608  11.786  12.147  1.00 30.12  ? 38  LEU D CD2 1 
ATOM   9696  N N   . TRP D 1 39  ? 33.462  14.214  8.064   1.00 24.32  ? 39  TRP D N   1 
ATOM   9697  C CA  . TRP D 1 39  ? 34.773  14.673  7.633   1.00 22.24  ? 39  TRP D CA  1 
ATOM   9698  C C   . TRP D 1 39  ? 35.121  16.050  8.202   1.00 23.89  ? 39  TRP D C   1 
ATOM   9699  O O   . TRP D 1 39  ? 36.241  16.533  8.029   1.00 25.60  ? 39  TRP D O   1 
ATOM   9700  C CB  . TRP D 1 39  ? 34.835  14.659  6.107   1.00 24.83  ? 39  TRP D CB  1 
ATOM   9701  C CG  . TRP D 1 39  ? 34.855  13.240  5.558   1.00 27.87  ? 39  TRP D CG  1 
ATOM   9702  C CD1 . TRP D 1 39  ? 33.781  12.470  5.240   1.00 27.91  ? 39  TRP D CD1 1 
ATOM   9703  C CD2 . TRP D 1 39  ? 36.013  12.427  5.327   1.00 27.75  ? 39  TRP D CD2 1 
ATOM   9704  N NE1 . TRP D 1 39  ? 34.196  11.229  4.805   1.00 30.70  ? 39  TRP D NE1 1 
ATOM   9705  C CE2 . TRP D 1 39  ? 35.562  11.178  4.853   1.00 28.06  ? 39  TRP D CE2 1 
ATOM   9706  C CE3 . TRP D 1 39  ? 37.389  12.637  5.469   1.00 28.79  ? 39  TRP D CE3 1 
ATOM   9707  C CZ2 . TRP D 1 39  ? 36.434  10.144  4.514   1.00 28.29  ? 39  TRP D CZ2 1 
ATOM   9708  C CZ3 . TRP D 1 39  ? 38.259  11.607  5.137   1.00 30.02  ? 39  TRP D CZ3 1 
ATOM   9709  C CH2 . TRP D 1 39  ? 37.776  10.375  4.660   1.00 27.61  ? 39  TRP D CH2 1 
ATOM   9710  N N   . HIS D 1 40  ? 34.175  16.682  8.889   1.00 21.78  ? 40  HIS D N   1 
ATOM   9711  C CA  . HIS D 1 40  ? 34.454  17.850  9.725   1.00 24.06  ? 40  HIS D CA  1 
ATOM   9712  C C   . HIS D 1 40  ? 34.988  17.487  11.113  1.00 22.87  ? 40  HIS D C   1 
ATOM   9713  O O   . HIS D 1 40  ? 35.535  18.361  11.801  1.00 22.47  ? 40  HIS D O   1 
ATOM   9714  C CB  . HIS D 1 40  ? 33.169  18.670  9.904   1.00 23.44  ? 40  HIS D CB  1 
ATOM   9715  C CG  . HIS D 1 40  ? 32.850  19.554  8.740   1.00 29.03  ? 40  HIS D CG  1 
ATOM   9716  N ND1 . HIS D 1 40  ? 33.764  20.433  8.208   1.00 28.91  ? 40  HIS D ND1 1 
ATOM   9717  C CD2 . HIS D 1 40  ? 31.731  19.672  7.988   1.00 27.29  ? 40  HIS D CD2 1 
ATOM   9718  C CE1 . HIS D 1 40  ? 33.211  21.083  7.200   1.00 26.42  ? 40  HIS D CE1 1 
ATOM   9719  N NE2 . HIS D 1 40  ? 31.979  20.635  7.043   1.00 24.29  ? 40  HIS D NE2 1 
ATOM   9720  N N   . ALA D 1 41  ? 34.839  16.233  11.550  1.00 21.89  ? 41  ALA D N   1 
ATOM   9721  C CA  . ALA D 1 41  ? 35.078  15.914  12.955  1.00 27.70  ? 41  ALA D CA  1 
ATOM   9722  C C   . ALA D 1 41  ? 36.544  16.089  13.326  1.00 27.90  ? 41  ALA D C   1 
ATOM   9723  O O   . ALA D 1 41  ? 37.441  15.723  12.562  1.00 28.67  ? 41  ALA D O   1 
ATOM   9724  C CB  . ALA D 1 41  ? 34.631  14.487  13.266  1.00 26.13  ? 41  ALA D CB  1 
ATOM   9725  N N   . GLU D 1 42  ? 36.774  16.705  14.479  1.00 27.87  ? 42  GLU D N   1 
ATOM   9726  C CA  . GLU D 1 42  ? 38.024  16.644  15.215  1.00 29.65  ? 42  GLU D CA  1 
ATOM   9727  C C   . GLU D 1 42  ? 37.777  15.887  16.508  1.00 37.19  ? 42  GLU D C   1 
ATOM   9728  O O   . GLU D 1 42  ? 36.631  15.606  16.870  1.00 36.09  ? 42  GLU D O   1 
ATOM   9729  C CB  . GLU D 1 42  ? 38.573  18.041  15.530  1.00 33.74  ? 42  GLU D CB  1 
ATOM   9730  C CG  . GLU D 1 42  ? 39.281  18.738  14.384  1.00 35.20  ? 42  GLU D CG  1 
ATOM   9731  C CD  . GLU D 1 42  ? 39.416  20.235  14.623  1.00 47.77  ? 42  GLU D CD  1 
ATOM   9732  O OE1 . GLU D 1 42  ? 40.104  20.645  15.590  1.00 54.26  ? 42  GLU D OE1 1 
ATOM   9733  O OE2 . GLU D 1 42  ? 38.820  21.011  13.849  1.00 48.88  ? 42  GLU D OE2 1 
ATOM   9734  N N   . ASP D 1 43  ? 38.873  15.585  17.208  1.00 40.58  ? 43  ASP D N   1 
ATOM   9735  C CA  . ASP D 1 43  ? 38.819  14.858  18.471  1.00 34.83  ? 43  ASP D CA  1 
ATOM   9736  C C   . ASP D 1 43  ? 37.790  15.467  19.414  1.00 34.44  ? 43  ASP D C   1 
ATOM   9737  O O   . ASP D 1 43  ? 37.793  16.676  19.661  1.00 37.98  ? 43  ASP D O   1 
ATOM   9738  C CB  . ASP D 1 43  ? 40.203  14.874  19.126  1.00 40.82  ? 43  ASP D CB  1 
ATOM   9739  C CG  . ASP D 1 43  ? 41.046  13.651  18.763  1.00 42.06  ? 43  ASP D CG  1 
ATOM   9740  O OD1 . ASP D 1 43  ? 40.608  12.842  17.912  1.00 39.45  ? 43  ASP D OD1 1 
ATOM   9741  O OD2 . ASP D 1 43  ? 42.153  13.504  19.335  1.00 43.29  ? 43  ASP D OD2 1 
ATOM   9742  N N   . GLY D 1 44  ? 36.895  14.626  19.924  1.00 35.73  ? 44  GLY D N   1 
ATOM   9743  C CA  . GLY D 1 44  ? 35.884  15.063  20.856  1.00 38.05  ? 44  GLY D CA  1 
ATOM   9744  C C   . GLY D 1 44  ? 34.642  15.682  20.248  1.00 40.67  ? 44  GLY D C   1 
ATOM   9745  O O   . GLY D 1 44  ? 33.695  15.968  20.989  1.00 41.61  ? 44  GLY D O   1 
ATOM   9746  N N   . ASP D 1 45  ? 34.607  15.909  18.936  1.00 40.43  ? 45  ASP D N   1 
ATOM   9747  C CA  . ASP D 1 45  ? 33.450  16.538  18.308  1.00 35.57  ? 45  ASP D CA  1 
ATOM   9748  C C   . ASP D 1 45  ? 32.213  15.652  18.419  1.00 40.72  ? 45  ASP D C   1 
ATOM   9749  O O   . ASP D 1 45  ? 32.293  14.433  18.634  1.00 39.77  ? 45  ASP D O   1 
ATOM   9750  C CB  . ASP D 1 45  ? 33.707  16.817  16.831  1.00 31.54  ? 45  ASP D CB  1 
ATOM   9751  C CG  . ASP D 1 45  ? 34.583  18.027  16.608  1.00 37.15  ? 45  ASP D CG  1 
ATOM   9752  O OD1 . ASP D 1 45  ? 34.893  18.728  17.606  1.00 33.00  ? 45  ASP D OD1 1 
ATOM   9753  O OD2 . ASP D 1 45  ? 34.954  18.271  15.431  1.00 31.36  ? 45  ASP D OD2 1 
ATOM   9754  N N   . VAL D 1 46  ? 31.057  16.296  18.254  1.00 35.87  ? 46  VAL D N   1 
ATOM   9755  C CA  . VAL D 1 46  ? 29.755  15.647  18.176  1.00 33.69  ? 46  VAL D CA  1 
ATOM   9756  C C   . VAL D 1 46  ? 29.152  15.955  16.813  1.00 35.61  ? 46  VAL D C   1 
ATOM   9757  O O   . VAL D 1 46  ? 29.080  17.125  16.410  1.00 33.75  ? 46  VAL D O   1 
ATOM   9758  C CB  . VAL D 1 46  ? 28.813  16.127  19.296  1.00 35.67  ? 46  VAL D CB  1 
ATOM   9759  C CG1 . VAL D 1 46  ? 27.392  15.689  19.003  1.00 36.65  ? 46  VAL D CG1 1 
ATOM   9760  C CG2 . VAL D 1 46  ? 29.281  15.605  20.647  1.00 39.56  ? 46  VAL D CG2 1 
ATOM   9761  N N   . LEU D 1 47  ? 28.711  14.919  16.108  1.00 34.32  ? 47  LEU D N   1 
ATOM   9762  C CA  . LEU D 1 47  ? 27.959  15.095  14.875  1.00 31.57  ? 47  LEU D CA  1 
ATOM   9763  C C   . LEU D 1 47  ? 26.507  14.728  15.126  1.00 35.08  ? 47  LEU D C   1 
ATOM   9764  O O   . LEU D 1 47  ? 26.222  13.683  15.717  1.00 37.22  ? 47  LEU D O   1 
ATOM   9765  C CB  . LEU D 1 47  ? 28.534  14.250  13.737  1.00 35.54  ? 47  LEU D CB  1 
ATOM   9766  C CG  . LEU D 1 47  ? 27.636  14.172  12.494  1.00 36.82  ? 47  LEU D CG  1 
ATOM   9767  C CD1 . LEU D 1 47  ? 27.478  15.531  11.792  1.00 33.50  ? 47  LEU D CD1 1 
ATOM   9768  C CD2 . LEU D 1 47  ? 28.195  13.168  11.538  1.00 30.59  ? 47  LEU D CD2 1 
ATOM   9769  N N   . VAL D 1 48  ? 25.595  15.595  14.705  1.00 31.25  ? 48  VAL D N   1 
ATOM   9770  C CA  . VAL D 1 48  ? 24.164  15.348  14.835  1.00 31.87  ? 48  VAL D CA  1 
ATOM   9771  C C   . VAL D 1 48  ? 23.636  14.943  13.473  1.00 38.02  ? 48  VAL D C   1 
ATOM   9772  O O   . VAL D 1 48  ? 23.819  15.675  12.497  1.00 45.47  ? 48  VAL D O   1 
ATOM   9773  C CB  . VAL D 1 48  ? 23.417  16.590  15.342  1.00 35.59  ? 48  VAL D CB  1 
ATOM   9774  C CG1 . VAL D 1 48  ? 21.934  16.318  15.342  1.00 37.51  ? 48  VAL D CG1 1 
ATOM   9775  C CG2 . VAL D 1 48  ? 23.890  16.989  16.715  1.00 32.36  ? 48  VAL D CG2 1 
ATOM   9776  N N   . ILE D 1 49  ? 22.961  13.802  13.397  1.00 38.39  ? 49  ILE D N   1 
ATOM   9777  C CA  . ILE D 1 49  ? 22.524  13.301  12.096  1.00 41.73  ? 49  ILE D CA  1 
ATOM   9778  C C   . ILE D 1 49  ? 21.027  13.004  12.126  1.00 44.93  ? 49  ILE D C   1 
ATOM   9779  O O   . ILE D 1 49  ? 20.538  12.329  13.046  1.00 47.68  ? 49  ILE D O   1 
ATOM   9780  C CB  . ILE D 1 49  ? 23.331  12.058  11.686  1.00 46.01  ? 49  ILE D CB  1 
ATOM   9781  C CG1 . ILE D 1 49  ? 23.304  11.002  12.781  1.00 44.27  ? 49  ILE D CG1 1 
ATOM   9782  C CG2 . ILE D 1 49  ? 24.776  12.392  11.415  1.00 46.35  ? 49  ILE D CG2 1 
ATOM   9783  C CD1 . ILE D 1 49  ? 22.410  9.865   12.442  1.00 51.55  ? 49  ILE D CD1 1 
ATOM   9784  N N   . PRO D 1 50  ? 20.258  13.479  11.147  1.00 40.74  ? 50  PRO D N   1 
ATOM   9785  C CA  . PRO D 1 50  ? 18.822  13.176  11.139  1.00 47.54  ? 50  PRO D CA  1 
ATOM   9786  C C   . PRO D 1 50  ? 18.480  11.792  10.615  1.00 45.99  ? 50  PRO D C   1 
ATOM   9787  O O   . PRO D 1 50  ? 17.383  11.300  10.916  1.00 45.57  ? 50  PRO D O   1 
ATOM   9788  C CB  . PRO D 1 50  ? 18.250  14.260  10.221  1.00 44.31  ? 50  PRO D CB  1 
ATOM   9789  C CG  . PRO D 1 50  ? 19.372  14.501  9.246   1.00 46.98  ? 50  PRO D CG  1 
ATOM   9790  C CD  . PRO D 1 50  ? 20.626  14.421  10.077  1.00 40.13  ? 50  PRO D CD  1 
ATOM   9791  N N   . ASP D 1 51  ? 19.351  11.157  9.839   1.00 45.36  ? 51  ASP D N   1 
ATOM   9792  C CA  . ASP D 1 51  ? 19.042  9.887   9.188   1.00 44.09  ? 51  ASP D CA  1 
ATOM   9793  C C   . ASP D 1 51  ? 19.906  8.785   9.825   1.00 47.21  ? 51  ASP D C   1 
ATOM   9794  O O   . ASP D 1 51  ? 20.000  8.755   11.054  1.00 50.21  ? 51  ASP D O   1 
ATOM   9795  C CB  . ASP D 1 51  ? 19.216  10.005  7.679   1.00 47.42  ? 51  ASP D CB  1 
ATOM   9796  C CG  . ASP D 1 51  ? 20.422  10.852  7.293   1.00 46.12  ? 51  ASP D CG  1 
ATOM   9797  O OD1 . ASP D 1 51  ? 21.425  10.792  8.033   1.00 51.03  ? 51  ASP D OD1 1 
ATOM   9798  O OD2 . ASP D 1 51  ? 20.381  11.574  6.260   1.00 46.65  ? 51  ASP D OD2 1 
ATOM   9799  N N   . THR D 1 52  ? 20.501  7.887   9.052   1.00 41.12  ? 52  THR D N   1 
ATOM   9800  C CA  . THR D 1 52  ? 21.308  6.807   9.595   1.00 47.82  ? 52  THR D CA  1 
ATOM   9801  C C   . THR D 1 52  ? 22.738  6.905   9.087   1.00 46.02  ? 52  THR D C   1 
ATOM   9802  O O   . THR D 1 52  ? 23.084  7.759   8.269   1.00 48.38  ? 52  THR D O   1 
ATOM   9803  C CB  . THR D 1 52  ? 20.747  5.432   9.216   1.00 47.60  ? 52  THR D CB  1 
ATOM   9804  O OG1 . THR D 1 52  ? 21.248  5.069   7.926   1.00 52.63  ? 52  THR D OG1 1 
ATOM   9805  C CG2 . THR D 1 52  ? 19.226  5.443   9.183   1.00 50.15  ? 52  THR D CG2 1 
ATOM   9806  N N   . VAL D 1 53  ? 23.572  5.994   9.570   1.00 47.18  ? 53  VAL D N   1 
ATOM   9807  C CA  . VAL D 1 53  ? 24.981  5.965   9.198   1.00 42.98  ? 53  VAL D CA  1 
ATOM   9808  C C   . VAL D 1 53  ? 25.474  4.535   9.356   1.00 42.38  ? 53  VAL D C   1 
ATOM   9809  O O   . VAL D 1 53  ? 25.117  3.846   10.319  1.00 40.93  ? 53  VAL D O   1 
ATOM   9810  C CB  . VAL D 1 53  ? 25.810  6.966   10.044  1.00 39.97  ? 53  VAL D CB  1 
ATOM   9811  C CG1 . VAL D 1 53  ? 25.919  6.504   11.478  1.00 40.60  ? 53  VAL D CG1 1 
ATOM   9812  C CG2 . VAL D 1 53  ? 27.204  7.174   9.439   1.00 38.18  ? 53  VAL D CG2 1 
ATOM   9813  N N   . ASP D 1 54  ? 26.267  4.077   8.386   1.00 40.61  ? 54  ASP D N   1 
ATOM   9814  C CA  . ASP D 1 54  ? 26.873  2.754   8.480   1.00 38.63  ? 54  ASP D CA  1 
ATOM   9815  C C   . ASP D 1 54  ? 27.680  2.664   9.774   1.00 36.02  ? 54  ASP D C   1 
ATOM   9816  O O   . ASP D 1 54  ? 28.504  3.548   10.040  1.00 37.43  ? 54  ASP D O   1 
ATOM   9817  C CB  . ASP D 1 54  ? 27.756  2.498   7.248   1.00 37.71  ? 54  ASP D CB  1 
ATOM   9818  C CG  . ASP D 1 54  ? 28.301  1.058   7.171   1.00 38.41  ? 54  ASP D CG  1 
ATOM   9819  O OD1 . ASP D 1 54  ? 28.882  0.580   8.172   1.00 32.74  ? 54  ASP D OD1 1 
ATOM   9820  O OD2 . ASP D 1 54  ? 28.172  0.423   6.088   1.00 33.48  ? 54  ASP D OD2 1 
ATOM   9821  N N   . PRO D 1 55  ? 27.425  1.663   10.631  1.00 36.40  ? 55  PRO D N   1 
ATOM   9822  C CA  . PRO D 1 55  ? 28.252  1.487   11.840  1.00 43.02  ? 55  PRO D CA  1 
ATOM   9823  C C   . PRO D 1 55  ? 29.757  1.625   11.613  1.00 38.41  ? 55  PRO D C   1 
ATOM   9824  O O   . PRO D 1 55  ? 30.455  2.162   12.481  1.00 35.43  ? 55  PRO D O   1 
ATOM   9825  C CB  . PRO D 1 55  ? 27.889  0.063   12.302  1.00 33.05  ? 55  PRO D CB  1 
ATOM   9826  C CG  . PRO D 1 55  ? 26.525  -0.204  11.730  1.00 40.80  ? 55  PRO D CG  1 
ATOM   9827  C CD  . PRO D 1 55  ? 26.225  0.812   10.654  1.00 37.33  ? 55  PRO D CD  1 
ATOM   9828  N N   . ASP D 1 56  ? 30.280  1.157   10.474  1.00 37.03  ? 56  ASP D N   1 
ATOM   9829  C CA  . ASP D 1 56  ? 31.719  1.266   10.235  1.00 35.89  ? 56  ASP D CA  1 
ATOM   9830  C C   . ASP D 1 56  ? 32.154  2.685   9.889   1.00 36.33  ? 56  ASP D C   1 
ATOM   9831  O O   . ASP D 1 56  ? 33.354  2.971   9.932   1.00 37.67  ? 56  ASP D O   1 
ATOM   9832  C CB  . ASP D 1 56  ? 32.160  0.340   9.100   1.00 38.23  ? 56  ASP D CB  1 
ATOM   9833  C CG  . ASP D 1 56  ? 32.099  -1.130  9.475   1.00 38.41  ? 56  ASP D CG  1 
ATOM   9834  O OD1 . ASP D 1 56  ? 32.906  -1.575  10.308  1.00 36.79  ? 56  ASP D OD1 1 
ATOM   9835  O OD2 . ASP D 1 56  ? 31.243  -1.852  8.921   1.00 51.04  ? 56  ASP D OD2 1 
ATOM   9836  N N   . PHE D 1 57  ? 31.219  3.582   9.559   1.00 31.53  ? 57  PHE D N   1 
ATOM   9837  C CA  . PHE D 1 57  ? 31.611  4.847   8.937   1.00 35.45  ? 57  PHE D CA  1 
ATOM   9838  C C   . PHE D 1 57  ? 32.465  5.750   9.826   1.00 33.72  ? 57  PHE D C   1 
ATOM   9839  O O   . PHE D 1 57  ? 33.542  6.178   9.367   1.00 33.35  ? 57  PHE D O   1 
ATOM   9840  C CB  . PHE D 1 57  ? 30.374  5.586   8.417   1.00 31.62  ? 57  PHE D CB  1 
ATOM   9841  C CG  . PHE D 1 57  ? 30.710  6.667   7.454   1.00 32.89  ? 57  PHE D CG  1 
ATOM   9842  C CD1 . PHE D 1 57  ? 31.357  6.360   6.283   1.00 27.42  ? 57  PHE D CD1 1 
ATOM   9843  C CD2 . PHE D 1 57  ? 30.407  7.996   7.729   1.00 33.28  ? 57  PHE D CD2 1 
ATOM   9844  C CE1 . PHE D 1 57  ? 31.696  7.352   5.373   1.00 33.82  ? 57  PHE D CE1 1 
ATOM   9845  C CE2 . PHE D 1 57  ? 30.741  8.997   6.829   1.00 34.06  ? 57  PHE D CE2 1 
ATOM   9846  C CZ  . PHE D 1 57  ? 31.395  8.666   5.635   1.00 31.81  ? 57  PHE D CZ  1 
ATOM   9847  N N   . PRO D 1 58  ? 32.072  6.097   11.061  1.00 31.59  ? 58  PRO D N   1 
ATOM   9848  C CA  . PRO D 1 58  ? 32.950  6.975   11.855  1.00 28.11  ? 58  PRO D CA  1 
ATOM   9849  C C   . PRO D 1 58  ? 34.343  6.417   12.015  1.00 27.49  ? 58  PRO D C   1 
ATOM   9850  O O   . PRO D 1 58  ? 35.320  7.172   11.948  1.00 30.60  ? 58  PRO D O   1 
ATOM   9851  C CB  . PRO D 1 58  ? 32.230  7.087   13.207  1.00 28.93  ? 58  PRO D CB  1 
ATOM   9852  C CG  . PRO D 1 58  ? 30.815  6.747   12.934  1.00 30.13  ? 58  PRO D CG  1 
ATOM   9853  C CD  . PRO D 1 58  ? 30.830  5.766   11.788  1.00 35.67  ? 58  PRO D CD  1 
ATOM   9854  N N   . GLY D 1 59  ? 34.470  5.107   12.214  1.00 29.68  ? 59  GLY D N   1 
ATOM   9855  C CA  . GLY D 1 59  ? 35.799  4.534   12.362  1.00 34.33  ? 59  GLY D CA  1 
ATOM   9856  C C   . GLY D 1 59  ? 36.649  4.736   11.125  1.00 29.53  ? 59  GLY D C   1 
ATOM   9857  O O   . GLY D 1 59  ? 37.842  5.038   11.215  1.00 29.79  ? 59  GLY D O   1 
ATOM   9858  N N   . TYR D 1 60  ? 36.040  4.598   9.951   1.00 28.31  ? 60  TYR D N   1 
ATOM   9859  C CA  . TYR D 1 60  ? 36.804  4.715   8.718   1.00 29.10  ? 60  TYR D CA  1 
ATOM   9860  C C   . TYR D 1 60  ? 37.228  6.155   8.479   1.00 29.06  ? 60  TYR D C   1 
ATOM   9861  O O   . TYR D 1 60  ? 38.367  6.421   8.088   1.00 26.72  ? 60  TYR D O   1 
ATOM   9862  C CB  . TYR D 1 60  ? 35.974  4.178   7.556   1.00 27.77  ? 60  TYR D CB  1 
ATOM   9863  C CG  . TYR D 1 60  ? 36.261  4.828   6.230   1.00 27.63  ? 60  TYR D CG  1 
ATOM   9864  C CD1 . TYR D 1 60  ? 37.386  4.481   5.505   1.00 25.61  ? 60  TYR D CD1 1 
ATOM   9865  C CD2 . TYR D 1 60  ? 35.404  5.790   5.704   1.00 26.89  ? 60  TYR D CD2 1 
ATOM   9866  C CE1 . TYR D 1 60  ? 37.648  5.057   4.295   1.00 29.12  ? 60  TYR D CE1 1 
ATOM   9867  C CE2 . TYR D 1 60  ? 35.660  6.371   4.487   1.00 27.99  ? 60  TYR D CE2 1 
ATOM   9868  C CZ  . TYR D 1 60  ? 36.790  6.004   3.787   1.00 28.01  ? 60  TYR D CZ  1 
ATOM   9869  O OH  . TYR D 1 60  ? 37.058  6.577   2.560   1.00 27.75  ? 60  TYR D OH  1 
ATOM   9870  N N   . VAL D 1 61  ? 36.320  7.100   8.708   1.00 32.90  ? 61  VAL D N   1 
ATOM   9871  C CA  . VAL D 1 61  ? 36.684  8.506   8.605   1.00 31.14  ? 61  VAL D CA  1 
ATOM   9872  C C   . VAL D 1 61  ? 37.810  8.834   9.579   1.00 31.93  ? 61  VAL D C   1 
ATOM   9873  O O   . VAL D 1 61  ? 38.766  9.542   9.232   1.00 31.17  ? 61  VAL D O   1 
ATOM   9874  C CB  . VAL D 1 61  ? 35.442  9.383   8.830   1.00 30.79  ? 61  VAL D CB  1 
ATOM   9875  C CG1 . VAL D 1 61  ? 35.854  10.782  9.166   1.00 31.44  ? 61  VAL D CG1 1 
ATOM   9876  C CG2 . VAL D 1 61  ? 34.569  9.356   7.586   1.00 29.12  ? 61  VAL D CG2 1 
ATOM   9877  N N   . ALA D 1 62  ? 37.744  8.290   10.796  1.00 33.02  ? 62  ALA D N   1 
ATOM   9878  C CA  . ALA D 1 62  ? 38.810  8.539   11.768  1.00 31.88  ? 62  ALA D CA  1 
ATOM   9879  C C   . ALA D 1 62  ? 40.154  7.978   11.302  1.00 35.15  ? 62  ALA D C   1 
ATOM   9880  O O   . ALA D 1 62  ? 41.179  8.666   11.380  1.00 37.32  ? 62  ALA D O   1 
ATOM   9881  C CB  . ALA D 1 62  ? 38.427  7.960   13.124  1.00 37.22  ? 62  ALA D CB  1 
ATOM   9882  N N   . ASP D 1 63  ? 40.178  6.725   10.824  1.00 32.69  ? 63  ASP D N   1 
ATOM   9883  C CA  . ASP D 1 63  ? 41.426  6.162   10.304  1.00 32.31  ? 63  ASP D CA  1 
ATOM   9884  C C   . ASP D 1 63  ? 42.032  7.069   9.241   1.00 35.20  ? 63  ASP D C   1 
ATOM   9885  O O   . ASP D 1 63  ? 43.255  7.238   9.172   1.00 32.47  ? 63  ASP D O   1 
ATOM   9886  C CB  . ASP D 1 63  ? 41.205  4.770   9.681   1.00 32.18  ? 63  ASP D CB  1 
ATOM   9887  C CG  . ASP D 1 63  ? 40.787  3.696   10.692  1.00 34.11  ? 63  ASP D CG  1 
ATOM   9888  O OD1 . ASP D 1 63  ? 40.869  3.914   11.919  1.00 35.71  ? 63  ASP D OD1 1 
ATOM   9889  O OD2 . ASP D 1 63  ? 40.350  2.610   10.233  1.00 32.57  ? 63  ASP D OD2 1 
ATOM   9890  N N   . THR D 1 64  ? 41.190  7.620   8.367   1.00 29.71  ? 64  THR D N   1 
ATOM   9891  C CA  . THR D 1 64  ? 41.699  8.391   7.249   1.00 29.24  ? 64  THR D CA  1 
ATOM   9892  C C   . THR D 1 64  ? 42.086  9.801   7.642   1.00 28.65  ? 64  THR D C   1 
ATOM   9893  O O   . THR D 1 64  ? 42.880  10.431  6.936   1.00 32.15  ? 64  THR D O   1 
ATOM   9894  C CB  . THR D 1 64  ? 40.666  8.439   6.130   1.00 28.50  ? 64  THR D CB  1 
ATOM   9895  O OG1 . THR D 1 64  ? 40.079  7.146   5.989   1.00 27.99  ? 64  THR D OG1 1 
ATOM   9896  C CG2 . THR D 1 64  ? 41.328  8.844   4.810   1.00 24.46  ? 64  THR D CG2 1 
ATOM   9897  N N   . LEU D 1 65  ? 41.542  10.311  8.735   1.00 30.47  ? 65  LEU D N   1 
ATOM   9898  C CA  . LEU D 1 65  ? 41.865  11.638  9.222   1.00 25.95  ? 65  LEU D CA  1 
ATOM   9899  C C   . LEU D 1 65  ? 42.907  11.615  10.327  1.00 35.15  ? 65  LEU D C   1 
ATOM   9900  O O   . LEU D 1 65  ? 43.281  12.678  10.825  1.00 38.91  ? 65  LEU D O   1 
ATOM   9901  C CB  . LEU D 1 65  ? 40.602  12.316  9.729   1.00 31.49  ? 65  LEU D CB  1 
ATOM   9902  C CG  . LEU D 1 65  ? 39.552  12.656  8.674   1.00 31.81  ? 65  LEU D CG  1 
ATOM   9903  C CD1 . LEU D 1 65  ? 38.382  13.340  9.358   1.00 31.05  ? 65  LEU D CD1 1 
ATOM   9904  C CD2 . LEU D 1 65  ? 40.165  13.555  7.603   1.00 27.85  ? 65  LEU D CD2 1 
ATOM   9905  N N   . GLY D 1 66  ? 43.367  10.433  10.729  1.00 35.69  ? 66  GLY D N   1 
ATOM   9906  C CA  . GLY D 1 66  ? 44.288  10.318  11.849  1.00 39.32  ? 66  GLY D CA  1 
ATOM   9907  C C   . GLY D 1 66  ? 43.763  10.899  13.144  1.00 39.13  ? 66  GLY D C   1 
ATOM   9908  O O   . GLY D 1 66  ? 44.533  11.493  13.907  1.00 40.47  ? 66  GLY D O   1 
ATOM   9909  N N   . ILE D 1 67  ? 42.468  10.744  13.415  1.00 38.15  ? 67  ILE D N   1 
ATOM   9910  C CA  . ILE D 1 67  ? 41.873  11.249  14.643  1.00 37.10  ? 67  ILE D CA  1 
ATOM   9911  C C   . ILE D 1 67  ? 41.412  10.062  15.481  1.00 42.81  ? 67  ILE D C   1 
ATOM   9912  O O   . ILE D 1 67  ? 41.392  8.921   15.023  1.00 42.92  ? 67  ILE D O   1 
ATOM   9913  C CB  . ILE D 1 67  ? 40.719  12.244  14.379  1.00 38.55  ? 67  ILE D CB  1 
ATOM   9914  C CG1 . ILE D 1 67  ? 39.555  11.565  13.642  1.00 36.45  ? 67  ILE D CG1 1 
ATOM   9915  C CG2 . ILE D 1 67  ? 41.222  13.430  13.570  1.00 35.11  ? 67  ILE D CG2 1 
ATOM   9916  C CD1 . ILE D 1 67  ? 38.209  12.175  13.925  1.00 35.12  ? 67  ILE D CD1 1 
ATOM   9917  N N   . ASP D 1 68  ? 41.067  10.349  16.738  1.00 46.08  ? 68  ASP D N   1 
ATOM   9918  C CA  . ASP D 1 68  ? 40.587  9.342   17.686  1.00 41.87  ? 68  ASP D CA  1 
ATOM   9919  C C   . ASP D 1 68  ? 39.072  9.236   17.550  1.00 44.01  ? 68  ASP D C   1 
ATOM   9920  O O   . ASP D 1 68  ? 38.313  9.978   18.183  1.00 45.48  ? 68  ASP D O   1 
ATOM   9921  C CB  . ASP D 1 68  ? 41.002  9.719   19.105  1.00 46.65  ? 68  ASP D CB  1 
ATOM   9922  C CG  . ASP D 1 68  ? 40.634  8.655   20.136  1.00 45.06  ? 68  ASP D CG  1 
ATOM   9923  O OD1 . ASP D 1 68  ? 40.537  7.457   19.776  1.00 46.57  ? 68  ASP D OD1 1 
ATOM   9924  O OD2 . ASP D 1 68  ? 40.458  9.030   21.315  1.00 46.65  ? 68  ASP D OD2 1 
ATOM   9925  N N   . GLY D 1 69  ? 38.624  8.281   16.734  1.00 36.56  ? 69  GLY D N   1 
ATOM   9926  C CA  . GLY D 1 69  ? 37.207  8.183   16.438  1.00 40.07  ? 69  GLY D CA  1 
ATOM   9927  C C   . GLY D 1 69  ? 36.361  7.841   17.648  1.00 46.69  ? 69  GLY D C   1 
ATOM   9928  O O   . GLY D 1 69  ? 35.167  8.162   17.685  1.00 42.94  ? 69  GLY D O   1 
ATOM   9929  N N   . THR D 1 70  ? 36.958  7.177   18.644  1.00 46.76  ? 70  THR D N   1 
ATOM   9930  C CA  . THR D 1 70  ? 36.271  6.942   19.908  1.00 45.28  ? 70  THR D CA  1 
ATOM   9931  C C   . THR D 1 70  ? 35.947  8.242   20.629  1.00 44.90  ? 70  THR D C   1 
ATOM   9932  O O   . THR D 1 70  ? 35.091  8.248   21.520  1.00 43.00  ? 70  THR D O   1 
ATOM   9933  C CB  . THR D 1 70  ? 37.119  6.055   20.826  1.00 47.10  ? 70  THR D CB  1 
ATOM   9934  O OG1 . THR D 1 70  ? 38.264  6.787   21.276  1.00 49.91  ? 70  THR D OG1 1 
ATOM   9935  C CG2 . THR D 1 70  ? 37.576  4.808   20.105  1.00 40.95  ? 70  THR D CG2 1 
ATOM   9936  N N   . SER D 1 71  ? 36.621  9.337   20.277  1.00 43.28  ? 71  SER D N   1 
ATOM   9937  C CA  . SER D 1 71  ? 36.293  10.643  20.829  1.00 47.26  ? 71  SER D CA  1 
ATOM   9938  C C   . SER D 1 71  ? 35.228  11.381  20.026  1.00 46.92  ? 71  SER D C   1 
ATOM   9939  O O   . SER D 1 71  ? 34.720  12.404  20.499  1.00 49.73  ? 71  SER D O   1 
ATOM   9940  C CB  . SER D 1 71  ? 37.556  11.512  20.941  1.00 42.55  ? 71  SER D CB  1 
ATOM   9941  O OG  . SER D 1 71  ? 38.006  11.940  19.674  1.00 41.28  ? 71  SER D OG  1 
ATOM   9942  N N   . VAL D 1 72  ? 34.857  10.891  18.846  1.00 45.65  ? 72  VAL D N   1 
ATOM   9943  C CA  . VAL D 1 72  ? 33.790  11.506  18.060  1.00 47.44  ? 72  VAL D CA  1 
ATOM   9944  C C   . VAL D 1 72  ? 32.461  10.835  18.390  1.00 45.53  ? 72  VAL D C   1 
ATOM   9945  O O   . VAL D 1 72  ? 32.372  9.603   18.462  1.00 42.63  ? 72  VAL D O   1 
ATOM   9946  C CB  . VAL D 1 72  ? 34.094  11.423  16.558  1.00 46.84  ? 72  VAL D CB  1 
ATOM   9947  C CG1 . VAL D 1 72  ? 33.047  12.226  15.773  1.00 41.32  ? 72  VAL D CG1 1 
ATOM   9948  C CG2 . VAL D 1 72  ? 35.496  11.942  16.301  1.00 40.81  ? 72  VAL D CG2 1 
ATOM   9949  N N   . HIS D 1 73  ? 31.427  11.649  18.583  1.00 46.07  ? 73  HIS D N   1 
ATOM   9950  C CA  . HIS D 1 73  ? 30.120  11.189  19.042  1.00 43.47  ? 73  HIS D CA  1 
ATOM   9951  C C   . HIS D 1 73  ? 29.070  11.552  18.001  1.00 43.68  ? 73  HIS D C   1 
ATOM   9952  O O   . HIS D 1 73  ? 28.899  12.732  17.674  1.00 41.53  ? 73  HIS D O   1 
ATOM   9953  C CB  . HIS D 1 73  ? 29.779  11.817  20.393  1.00 44.70  ? 73  HIS D CB  1 
ATOM   9954  C CG  . HIS D 1 73  ? 30.640  11.324  21.513  1.00 52.63  ? 73  HIS D CG  1 
ATOM   9955  N ND1 . HIS D 1 73  ? 31.986  11.608  21.597  1.00 50.48  ? 73  HIS D ND1 1 
ATOM   9956  C CD2 . HIS D 1 73  ? 30.351  10.550  22.588  1.00 59.86  ? 73  HIS D CD2 1 
ATOM   9957  C CE1 . HIS D 1 73  ? 32.488  11.038  22.679  1.00 54.90  ? 73  HIS D CE1 1 
ATOM   9958  N NE2 . HIS D 1 73  ? 31.518  10.387  23.295  1.00 57.37  ? 73  HIS D NE2 1 
ATOM   9959  N N   . VAL D 1 74  ? 28.377  10.544  17.480  1.00 36.76  ? 74  VAL D N   1 
ATOM   9960  C CA  . VAL D 1 74  ? 27.279  10.740  16.536  1.00 36.93  ? 74  VAL D CA  1 
ATOM   9961  C C   . VAL D 1 74  ? 25.971  10.735  17.320  1.00 43.13  ? 74  VAL D C   1 
ATOM   9962  O O   . VAL D 1 74  ? 25.577  9.710   17.890  1.00 47.32  ? 74  VAL D O   1 
ATOM   9963  C CB  . VAL D 1 74  ? 27.279  9.661   15.448  1.00 38.57  ? 74  VAL D CB  1 
ATOM   9964  C CG1 . VAL D 1 74  ? 25.970  9.678   14.670  1.00 37.43  ? 74  VAL D CG1 1 
ATOM   9965  C CG2 . VAL D 1 74  ? 28.466  9.867   14.524  1.00 35.27  ? 74  VAL D CG2 1 
ATOM   9966  N N   . GLU D 1 75  ? 25.287  11.873  17.356  1.00 41.98  ? 75  GLU D N   1 
ATOM   9967  C CA  . GLU D 1 75  ? 24.013  11.995  18.058  1.00 44.50  ? 75  GLU D CA  1 
ATOM   9968  C C   . GLU D 1 75  ? 22.886  11.844  17.046  1.00 42.67  ? 75  GLU D C   1 
ATOM   9969  O O   . GLU D 1 75  ? 22.691  12.704  16.180  1.00 43.51  ? 75  GLU D O   1 
ATOM   9970  C CB  . GLU D 1 75  ? 23.914  13.324  18.800  1.00 38.96  ? 75  GLU D CB  1 
ATOM   9971  C CG  . GLU D 1 75  ? 24.285  13.228  20.275  1.00 49.75  ? 75  GLU D CG  1 
ATOM   9972  C CD  . GLU D 1 75  ? 23.606  12.063  20.990  1.00 48.95  ? 75  GLU D CD  1 
ATOM   9973  O OE1 . GLU D 1 75  ? 22.369  11.918  20.868  1.00 48.76  ? 75  GLU D OE1 1 
ATOM   9974  O OE2 . GLU D 1 75  ? 24.315  11.297  21.681  1.00 48.81  ? 75  GLU D OE2 1 
ATOM   9975  N N   . ARG D 1 76  ? 22.139  10.762  17.169  1.00 46.64  ? 76  ARG D N   1 
ATOM   9976  C CA  . ARG D 1 76  ? 21.141  10.380  16.181  1.00 46.95  ? 76  ARG D CA  1 
ATOM   9977  C C   . ARG D 1 76  ? 19.785  10.926  16.617  1.00 52.98  ? 76  ARG D C   1 
ATOM   9978  O O   . ARG D 1 76  ? 19.218  10.487  17.622  1.00 51.24  ? 76  ARG D O   1 
ATOM   9979  C CB  . ARG D 1 76  ? 21.110  8.860   16.020  1.00 47.56  ? 76  ARG D CB  1 
ATOM   9980  C CG  . ARG D 1 76  ? 22.370  8.295   15.388  1.00 48.46  ? 76  ARG D CG  1 
ATOM   9981  C CD  . ARG D 1 76  ? 22.532  6.809   15.608  1.00 56.12  ? 76  ARG D CD  1 
ATOM   9982  N NE  . ARG D 1 76  ? 22.757  6.123   14.340  1.00 55.15  ? 76  ARG D NE  1 
ATOM   9983  C CZ  . ARG D 1 76  ? 21.814  5.479   13.664  1.00 59.42  ? 76  ARG D CZ  1 
ATOM   9984  N NH1 . ARG D 1 76  ? 20.576  5.382   14.128  1.00 60.21  ? 76  ARG D NH1 1 
ATOM   9985  N NH2 . ARG D 1 76  ? 22.119  4.925   12.488  1.00 53.64  ? 76  ARG D NH2 1 
ATOM   9986  N N   . THR D 1 77  ? 19.290  11.914  15.891  1.00 53.46  ? 77  THR D N   1 
ATOM   9987  C CA  . THR D 1 77  ? 17.881  12.260  15.947  1.00 56.33  ? 77  THR D CA  1 
ATOM   9988  C C   . THR D 1 77  ? 17.200  11.541  14.802  1.00 54.92  ? 77  THR D C   1 
ATOM   9989  O O   . THR D 1 77  ? 17.766  11.423  13.712  1.00 60.27  ? 77  THR D O   1 
ATOM   9990  C CB  . THR D 1 77  ? 17.676  13.764  15.805  1.00 50.65  ? 77  THR D CB  1 
ATOM   9991  O OG1 . THR D 1 77  ? 17.634  14.089  14.410  1.00 46.10  ? 77  THR D OG1 1 
ATOM   9992  C CG2 . THR D 1 77  ? 18.820  14.510  16.460  1.00 50.19  ? 77  THR D CG2 1 
ATOM   9993  N N   . GLN D 1 78  ? 15.999  11.047  15.033  1.00 49.83  ? 78  GLN D N   1 
ATOM   9994  C CA  . GLN D 1 78  ? 15.367  10.298  13.961  1.00 55.77  ? 78  GLN D CA  1 
ATOM   9995  C C   . GLN D 1 78  ? 14.513  11.187  13.072  1.00 53.71  ? 78  GLN D C   1 
ATOM   9996  O O   . GLN D 1 78  ? 13.832  10.676  12.180  1.00 51.45  ? 78  GLN D O   1 
ATOM   9997  C CB  . GLN D 1 78  ? 14.554  9.132   14.538  1.00 59.21  ? 78  GLN D CB  1 
ATOM   9998  C CG  . GLN D 1 78  ? 15.318  8.316   15.592  1.00 55.63  ? 78  GLN D CG  1 
ATOM   9999  C CD  . GLN D 1 78  ? 15.660  6.894   15.140  1.00 64.44  ? 78  GLN D CD  1 
ATOM   10000 O OE1 . GLN D 1 78  ? 15.131  6.396   14.144  1.00 67.48  ? 78  GLN D OE1 1 
ATOM   10001 N NE2 . GLN D 1 78  ? 16.534  6.231   15.889  1.00 53.48  ? 78  GLN D NE2 1 
ATOM   10002 N N   . THR D 1 79  ? 14.553  12.501  13.287  1.00 52.82  ? 79  THR D N   1 
ATOM   10003 C CA  . THR D 1 79  ? 13.819  13.504  12.529  1.00 51.74  ? 79  THR D CA  1 
ATOM   10004 C C   . THR D 1 79  ? 14.803  14.480  11.904  1.00 51.39  ? 79  THR D C   1 
ATOM   10005 O O   . THR D 1 79  ? 15.943  14.605  12.371  1.00 49.22  ? 79  THR D O   1 
ATOM   10006 C CB  . THR D 1 79  ? 12.846  14.298  13.420  1.00 50.79  ? 79  THR D CB  1 
ATOM   10007 O OG1 . THR D 1 79  ? 13.452  14.542  14.697  1.00 50.78  ? 79  THR D OG1 1 
ATOM   10008 C CG2 . THR D 1 79  ? 11.532  13.552  13.608  1.00 48.41  ? 79  THR D CG2 1 
ATOM   10009 N N   . PRO D 1 80  ? 14.396  15.202  10.857  1.00 44.39  ? 80  PRO D N   1 
ATOM   10010 C CA  . PRO D 1 80  ? 15.232  16.300  10.357  1.00 41.01  ? 80  PRO D CA  1 
ATOM   10011 C C   . PRO D 1 80  ? 15.401  17.383  11.417  1.00 40.17  ? 80  PRO D C   1 
ATOM   10012 O O   . PRO D 1 80  ? 14.592  17.529  12.340  1.00 41.97  ? 80  PRO D O   1 
ATOM   10013 C CB  . PRO D 1 80  ? 14.455  16.819  9.138   1.00 37.57  ? 80  PRO D CB  1 
ATOM   10014 C CG  . PRO D 1 80  ? 13.550  15.698  8.744   1.00 42.88  ? 80  PRO D CG  1 
ATOM   10015 C CD  . PRO D 1 80  ? 13.183  15.022  10.042  1.00 43.30  ? 80  PRO D CD  1 
ATOM   10016 N N   . LEU D 1 81  ? 16.475  18.155  11.267  1.00 37.56  ? 81  LEU D N   1 
ATOM   10017 C CA  . LEU D 1 81  ? 16.911  19.113  12.282  1.00 32.01  ? 81  LEU D CA  1 
ATOM   10018 C C   . LEU D 1 81  ? 16.201  20.448  12.071  1.00 38.04  ? 81  LEU D C   1 
ATOM   10019 O O   . LEU D 1 81  ? 16.802  21.479  11.758  1.00 35.42  ? 81  LEU D O   1 
ATOM   10020 C CB  . LEU D 1 81  ? 18.426  19.268  12.240  1.00 31.04  ? 81  LEU D CB  1 
ATOM   10021 C CG  . LEU D 1 81  ? 19.160  17.941  12.500  1.00 40.86  ? 81  LEU D CG  1 
ATOM   10022 C CD1 . LEU D 1 81  ? 20.702  18.111  12.500  1.00 31.89  ? 81  LEU D CD1 1 
ATOM   10023 C CD2 . LEU D 1 81  ? 18.671  17.283  13.795  1.00 31.61  ? 81  LEU D CD2 1 
ATOM   10024 N N   . SER D 1 82  ? 14.884  20.410  12.249  1.00 38.72  ? 82  SER D N   1 
ATOM   10025 C CA  . SER D 1 82  ? 14.097  21.611  12.055  1.00 33.47  ? 82  SER D CA  1 
ATOM   10026 C C   . SER D 1 82  ? 14.265  22.536  13.253  1.00 34.82  ? 82  SER D C   1 
ATOM   10027 O O   . SER D 1 82  ? 14.908  22.197  14.252  1.00 39.31  ? 82  SER D O   1 
ATOM   10028 C CB  . SER D 1 82  ? 12.628  21.262  11.843  1.00 34.29  ? 82  SER D CB  1 
ATOM   10029 O OG  . SER D 1 82  ? 12.148  20.546  12.957  1.00 34.07  ? 82  SER D OG  1 
ATOM   10030 N N   . GLU D 1 83  ? 13.686  23.729  13.140  1.00 30.30  ? 83  GLU D N   1 
ATOM   10031 C CA  . GLU D 1 83  ? 13.756  24.683  14.241  1.00 35.81  ? 83  GLU D CA  1 
ATOM   10032 C C   . GLU D 1 83  ? 13.048  24.150  15.482  1.00 33.85  ? 83  GLU D C   1 
ATOM   10033 O O   . GLU D 1 83  ? 13.463  24.425  16.619  1.00 29.67  ? 83  GLU D O   1 
ATOM   10034 C CB  . GLU D 1 83  ? 13.153  26.002  13.792  1.00 30.64  ? 83  GLU D CB  1 
ATOM   10035 C CG  . GLU D 1 83  ? 13.916  26.629  12.658  1.00 33.35  ? 83  GLU D CG  1 
ATOM   10036 C CD  . GLU D 1 83  ? 15.240  27.206  13.106  1.00 32.66  ? 83  GLU D CD  1 
ATOM   10037 O OE1 . GLU D 1 83  ? 16.260  26.490  13.019  1.00 38.13  ? 83  GLU D OE1 1 
ATOM   10038 O OE2 . GLU D 1 83  ? 15.273  28.390  13.534  1.00 36.58  ? 83  GLU D OE2 1 
ATOM   10039 N N   . ALA D 1 84  ? 11.979  23.382  15.278  1.00 35.76  ? 84  ALA D N   1 
ATOM   10040 C CA  . ALA D 1 84  ? 11.286  22.753  16.395  1.00 37.97  ? 84  ALA D CA  1 
ATOM   10041 C C   . ALA D 1 84  ? 12.222  21.820  17.148  1.00 38.76  ? 84  ALA D C   1 
ATOM   10042 O O   . ALA D 1 84  ? 12.302  21.859  18.382  1.00 37.99  ? 84  ALA D O   1 
ATOM   10043 C CB  . ALA D 1 84  ? 10.063  21.996  15.878  1.00 33.58  ? 84  ALA D CB  1 
ATOM   10044 N N   . VAL D 1 85  ? 12.972  20.998  16.411  1.00 34.14  ? 85  VAL D N   1 
ATOM   10045 C CA  . VAL D 1 85  ? 13.899  20.068  17.048  1.00 37.33  ? 85  VAL D CA  1 
ATOM   10046 C C   . VAL D 1 85  ? 14.991  20.821  17.807  1.00 36.54  ? 85  VAL D C   1 
ATOM   10047 O O   . VAL D 1 85  ? 15.255  20.534  18.980  1.00 29.85  ? 85  VAL D O   1 
ATOM   10048 C CB  . VAL D 1 85  ? 14.483  19.102  16.004  1.00 39.52  ? 85  VAL D CB  1 
ATOM   10049 C CG1 . VAL D 1 85  ? 15.086  17.905  16.696  1.00 42.50  ? 85  VAL D CG1 1 
ATOM   10050 C CG2 . VAL D 1 85  ? 13.384  18.660  15.060  1.00 38.20  ? 85  VAL D CG2 1 
ATOM   10051 N N   . LEU D 1 86  ? 15.633  21.810  17.159  1.00 33.56  ? 86  LEU D N   1 
ATOM   10052 C CA  . LEU D 1 86  ? 16.689  22.573  17.832  1.00 30.38  ? 86  LEU D CA  1 
ATOM   10053 C C   . LEU D 1 86  ? 16.184  23.340  19.059  1.00 33.07  ? 86  LEU D C   1 
ATOM   10054 O O   . LEU D 1 86  ? 17.001  23.762  19.890  1.00 31.58  ? 86  LEU D O   1 
ATOM   10055 C CB  . LEU D 1 86  ? 17.365  23.547  16.854  1.00 29.47  ? 86  LEU D CB  1 
ATOM   10056 C CG  . LEU D 1 86  ? 17.902  22.980  15.532  1.00 34.75  ? 86  LEU D CG  1 
ATOM   10057 C CD1 . LEU D 1 86  ? 18.515  24.101  14.665  1.00 35.03  ? 86  LEU D CD1 1 
ATOM   10058 C CD2 . LEU D 1 86  ? 18.916  21.883  15.789  1.00 32.90  ? 86  LEU D CD2 1 
ATOM   10059 N N   . GLN D 1 87  ? 14.867  23.514  19.208  1.00 35.06  ? 87  GLN D N   1 
ATOM   10060 C CA  . GLN D 1 87  ? 14.283  24.116  20.407  1.00 38.55  ? 87  GLN D CA  1 
ATOM   10061 C C   . GLN D 1 87  ? 13.701  23.097  21.384  1.00 39.81  ? 87  GLN D C   1 
ATOM   10062 O O   . GLN D 1 87  ? 13.207  23.494  22.449  1.00 41.02  ? 87  GLN D O   1 
ATOM   10063 C CB  . GLN D 1 87  ? 13.189  25.117  20.022  1.00 32.67  ? 87  GLN D CB  1 
ATOM   10064 C CG  . GLN D 1 87  ? 13.736  26.381  19.405  1.00 30.47  ? 87  GLN D CG  1 
ATOM   10065 C CD  . GLN D 1 87  ? 12.774  27.540  19.542  1.00 41.44  ? 87  GLN D CD  1 
ATOM   10066 O OE1 . GLN D 1 87  ? 11.842  27.692  18.741  1.00 43.14  ? 87  GLN D OE1 1 
ATOM   10067 N NE2 . GLN D 1 87  ? 12.990  28.367  20.564  1.00 36.05  ? 87  GLN D NE2 1 
ATOM   10068 N N   . ASP D 1 88  ? 13.744  21.803  21.059  1.00 38.32  ? 88  ASP D N   1 
ATOM   10069 C CA  . ASP D 1 88  ? 13.122  20.811  21.923  1.00 39.62  ? 88  ASP D CA  1 
ATOM   10070 C C   . ASP D 1 88  ? 14.008  20.559  23.136  1.00 42.94  ? 88  ASP D C   1 
ATOM   10071 O O   . ASP D 1 88  ? 15.207  20.313  22.980  1.00 43.30  ? 88  ASP D O   1 
ATOM   10072 C CB  . ASP D 1 88  ? 12.869  19.501  21.183  1.00 40.43  ? 88  ASP D CB  1 
ATOM   10073 C CG  . ASP D 1 88  ? 12.175  18.459  22.067  1.00 48.68  ? 88  ASP D CG  1 
ATOM   10074 O OD1 . ASP D 1 88  ? 12.751  18.078  23.105  1.00 47.08  ? 88  ASP D OD1 1 
ATOM   10075 O OD2 . ASP D 1 88  ? 11.047  18.034  21.741  1.00 50.72  ? 88  ASP D OD2 1 
ATOM   10076 N N   . PRO D 1 89  ? 13.457  20.600  24.351  1.00 44.14  ? 89  PRO D N   1 
ATOM   10077 C CA  . PRO D 1 89  ? 14.306  20.404  25.535  1.00 42.90  ? 89  PRO D CA  1 
ATOM   10078 C C   . PRO D 1 89  ? 14.896  19.009  25.626  1.00 44.53  ? 89  PRO D C   1 
ATOM   10079 O O   . PRO D 1 89  ? 16.002  18.864  26.159  1.00 41.02  ? 89  PRO D O   1 
ATOM   10080 C CB  . PRO D 1 89  ? 13.356  20.704  26.703  1.00 44.27  ? 89  PRO D CB  1 
ATOM   10081 C CG  . PRO D 1 89  ? 12.003  20.457  26.160  1.00 48.14  ? 89  PRO D CG  1 
ATOM   10082 C CD  . PRO D 1 89  ? 12.059  20.877  24.709  1.00 40.09  ? 89  PRO D CD  1 
ATOM   10083 N N   . GLU D 1 90  ? 14.201  17.983  25.118  1.00 46.91  ? 90  GLU D N   1 
ATOM   10084 C CA  . GLU D 1 90  ? 14.777  16.640  25.106  1.00 47.02  ? 90  GLU D CA  1 
ATOM   10085 C C   . GLU D 1 90  ? 16.021  16.598  24.233  1.00 48.93  ? 90  GLU D C   1 
ATOM   10086 O O   . GLU D 1 90  ? 17.003  15.925  24.566  1.00 48.76  ? 90  GLU D O   1 
ATOM   10087 C CB  . GLU D 1 90  ? 13.749  15.617  24.606  1.00 53.40  ? 90  GLU D CB  1 
ATOM   10088 C CG  . GLU D 1 90  ? 12.322  15.861  25.080  1.00 56.89  ? 90  GLU D CG  1 
ATOM   10089 C CD  . GLU D 1 90  ? 11.452  14.615  25.027  1.00 67.87  ? 90  GLU D CD  1 
ATOM   10090 O OE1 . GLU D 1 90  ? 11.116  14.077  26.106  1.00 67.43  ? 90  GLU D OE1 1 
ATOM   10091 O OE2 . GLU D 1 90  ? 11.092  14.189  23.904  1.00 68.76  ? 90  GLU D OE2 1 
ATOM   10092 N N   . PHE D 1 91  ? 15.984  17.302  23.098  1.00 44.43  ? 91  PHE D N   1 
ATOM   10093 C CA  . PHE D 1 91  ? 17.140  17.370  22.215  1.00 41.82  ? 91  PHE D CA  1 
ATOM   10094 C C   . PHE D 1 91  ? 18.258  18.174  22.856  1.00 41.58  ? 91  PHE D C   1 
ATOM   10095 O O   . PHE D 1 91  ? 19.436  17.807  22.758  1.00 40.50  ? 91  PHE D O   1 
ATOM   10096 C CB  . PHE D 1 91  ? 16.736  17.987  20.871  1.00 39.66  ? 91  PHE D CB  1 
ATOM   10097 C CG  . PHE D 1 91  ? 17.889  18.200  19.926  1.00 36.13  ? 91  PHE D CG  1 
ATOM   10098 C CD1 . PHE D 1 91  ? 18.440  17.139  19.228  1.00 37.22  ? 91  PHE D CD1 1 
ATOM   10099 C CD2 . PHE D 1 91  ? 18.430  19.462  19.749  1.00 34.75  ? 91  PHE D CD2 1 
ATOM   10100 C CE1 . PHE D 1 91  ? 19.500  17.338  18.354  1.00 38.81  ? 91  PHE D CE1 1 
ATOM   10101 C CE2 . PHE D 1 91  ? 19.492  19.665  18.884  1.00 32.62  ? 91  PHE D CE2 1 
ATOM   10102 C CZ  . PHE D 1 91  ? 20.026  18.599  18.184  1.00 33.53  ? 91  PHE D CZ  1 
ATOM   10103 N N   . ILE D 1 92  ? 17.908  19.265  23.530  1.00 42.34  ? 92  ILE D N   1 
ATOM   10104 C CA  . ILE D 1 92  ? 18.933  20.120  24.108  1.00 37.73  ? 92  ILE D CA  1 
ATOM   10105 C C   . ILE D 1 92  ? 19.667  19.394  25.229  1.00 43.55  ? 92  ILE D C   1 
ATOM   10106 O O   . ILE D 1 92  ? 20.892  19.503  25.356  1.00 43.60  ? 92  ILE D O   1 
ATOM   10107 C CB  . ILE D 1 92  ? 18.304  21.439  24.572  1.00 41.47  ? 92  ILE D CB  1 
ATOM   10108 C CG1 . ILE D 1 92  ? 17.757  22.191  23.357  1.00 36.44  ? 92  ILE D CG1 1 
ATOM   10109 C CG2 . ILE D 1 92  ? 19.317  22.279  25.334  1.00 42.35  ? 92  ILE D CG2 1 
ATOM   10110 C CD1 . ILE D 1 92  ? 17.160  23.539  23.691  1.00 36.98  ? 92  ILE D CD1 1 
ATOM   10111 N N   . ASP D 1 93  ? 18.941  18.604  26.029  1.00 45.31  ? 93  ASP D N   1 
ATOM   10112 C CA  . ASP D 1 93  ? 19.602  17.829  27.072  1.00 44.93  ? 93  ASP D CA  1 
ATOM   10113 C C   . ASP D 1 93  ? 20.525  16.765  26.489  1.00 44.67  ? 93  ASP D C   1 
ATOM   10114 O O   . ASP D 1 93  ? 21.525  16.409  27.123  1.00 42.69  ? 93  ASP D O   1 
ATOM   10115 C CB  . ASP D 1 93  ? 18.576  17.172  27.992  1.00 47.89  ? 93  ASP D CB  1 
ATOM   10116 C CG  . ASP D 1 93  ? 19.211  16.623  29.267  1.00 62.08  ? 93  ASP D CG  1 
ATOM   10117 O OD1 . ASP D 1 93  ? 19.810  17.428  30.025  1.00 55.04  ? 93  ASP D OD1 1 
ATOM   10118 O OD2 . ASP D 1 93  ? 19.137  15.388  29.493  1.00 61.39  ? 93  ASP D OD2 1 
ATOM   10119 N N   . ARG D 1 94  ? 20.207  16.239  25.300  1.00 40.08  ? 94  ARG D N   1 
ATOM   10120 C CA  . ARG D 1 94  ? 21.089  15.258  24.674  1.00 40.06  ? 94  ARG D CA  1 
ATOM   10121 C C   . ARG D 1 94  ? 22.461  15.861  24.389  1.00 37.07  ? 94  ARG D C   1 
ATOM   10122 O O   . ARG D 1 94  ? 23.486  15.319  24.817  1.00 42.78  ? 94  ARG D O   1 
ATOM   10123 C CB  . ARG D 1 94  ? 20.447  14.709  23.398  1.00 42.28  ? 94  ARG D CB  1 
ATOM   10124 C CG  . ARG D 1 94  ? 19.154  13.959  23.669  1.00 47.65  ? 94  ARG D CG  1 
ATOM   10125 C CD  . ARG D 1 94  ? 18.514  13.440  22.400  1.00 48.78  ? 94  ARG D CD  1 
ATOM   10126 N NE  . ARG D 1 94  ? 19.199  12.250  21.919  1.00 59.23  ? 94  ARG D NE  1 
ATOM   10127 C CZ  . ARG D 1 94  ? 18.585  11.166  21.464  1.00 64.39  ? 94  ARG D CZ  1 
ATOM   10128 N NH1 . ARG D 1 94  ? 17.264  11.097  21.389  1.00 64.26  ? 94  ARG D NH1 1 
ATOM   10129 N NH2 . ARG D 1 94  ? 19.314  10.121  21.083  1.00 61.52  ? 94  ARG D NH2 1 
ATOM   10130 N N   . LEU D 1 95  ? 22.503  17.006  23.695  1.00 38.07  ? 95  LEU D N   1 
ATOM   10131 C CA  . LEU D 1 95  ? 23.785  17.664  23.439  1.00 36.87  ? 95  LEU D CA  1 
ATOM   10132 C C   . LEU D 1 95  ? 24.413  18.204  24.716  1.00 35.69  ? 95  LEU D C   1 
ATOM   10133 O O   . LEU D 1 95  ? 25.646  18.318  24.791  1.00 37.52  ? 95  LEU D O   1 
ATOM   10134 C CB  . LEU D 1 95  ? 23.624  18.818  22.444  1.00 36.90  ? 95  LEU D CB  1 
ATOM   10135 C CG  . LEU D 1 95  ? 22.941  18.573  21.099  1.00 32.25  ? 95  LEU D CG  1 
ATOM   10136 C CD1 . LEU D 1 95  ? 22.818  19.887  20.371  1.00 28.69  ? 95  LEU D CD1 1 
ATOM   10137 C CD2 . LEU D 1 95  ? 23.725  17.575  20.286  1.00 34.18  ? 95  LEU D CD2 1 
ATOM   10138 N N   . ALA D 1 96  ? 23.590  18.574  25.710  1.00 31.10  ? 96  ALA D N   1 
ATOM   10139 C CA  . ALA D 1 96  ? 24.122  19.189  26.924  1.00 36.60  ? 96  ALA D CA  1 
ATOM   10140 C C   . ALA D 1 96  ? 24.978  18.223  27.724  1.00 34.33  ? 96  ALA D C   1 
ATOM   10141 O O   . ALA D 1 96  ? 25.865  18.663  28.465  1.00 34.92  ? 96  ALA D O   1 
ATOM   10142 C CB  . ALA D 1 96  ? 22.998  19.721  27.806  1.00 34.76  ? 96  ALA D CB  1 
ATOM   10143 N N   . ALA D 1 97  ? 24.721  16.917  27.597  1.00 36.82  ? 97  ALA D N   1 
ATOM   10144 C CA  . ALA D 1 97  ? 25.507  15.884  28.268  1.00 40.39  ? 97  ALA D CA  1 
ATOM   10145 C C   . ALA D 1 97  ? 26.851  15.635  27.607  1.00 42.89  ? 97  ALA D C   1 
ATOM   10146 O O   . ALA D 1 97  ? 27.656  14.873  28.154  1.00 44.12  ? 97  ALA D O   1 
ATOM   10147 C CB  . ALA D 1 97  ? 24.730  14.567  28.314  1.00 38.96  ? 97  ALA D CB  1 
ATOM   10148 N N   . HIS D 1 98  ? 27.096  16.212  26.429  1.00 40.47  ? 98  HIS D N   1 
ATOM   10149 C CA  . HIS D 1 98  ? 28.434  16.255  25.857  1.00 37.72  ? 98  HIS D CA  1 
ATOM   10150 C C   . HIS D 1 98  ? 29.138  17.559  26.184  1.00 39.41  ? 98  HIS D C   1 
ATOM   10151 O O   . HIS D 1 98  ? 30.342  17.570  26.459  1.00 38.42  ? 98  HIS D O   1 
ATOM   10152 C CB  . HIS D 1 98  ? 28.377  16.089  24.334  1.00 42.76  ? 98  HIS D CB  1 
ATOM   10153 C CG  . HIS D 1 98  ? 27.749  14.809  23.875  1.00 40.81  ? 98  HIS D CG  1 
ATOM   10154 N ND1 . HIS D 1 98  ? 28.359  13.582  24.026  1.00 45.27  ? 98  HIS D ND1 1 
ATOM   10155 C CD2 . HIS D 1 98  ? 26.573  14.570  23.245  1.00 39.06  ? 98  HIS D CD2 1 
ATOM   10156 C CE1 . HIS D 1 98  ? 27.579  12.641  23.523  1.00 47.79  ? 98  HIS D CE1 1 
ATOM   10157 N NE2 . HIS D 1 98  ? 26.488  13.214  23.045  1.00 42.51  ? 98  HIS D NE2 1 
ATOM   10158 N N   . THR D 1 99  ? 28.388  18.654  26.193  1.00 37.11  ? 99  THR D N   1 
ATOM   10159 C CA  . THR D 1 99  ? 28.957  19.981  26.339  1.00 38.89  ? 99  THR D CA  1 
ATOM   10160 C C   . THR D 1 99  ? 29.130  20.412  27.782  1.00 38.45  ? 99  THR D C   1 
ATOM   10161 O O   . THR D 1 99  ? 29.940  21.304  28.045  1.00 43.80  ? 99  THR D O   1 
ATOM   10162 C CB  . THR D 1 99  ? 28.086  20.990  25.593  1.00 40.46  ? 99  THR D CB  1 
ATOM   10163 O OG1 . THR D 1 99  ? 26.736  20.882  26.058  1.00 39.01  ? 99  THR D OG1 1 
ATOM   10164 C CG2 . THR D 1 99  ? 28.132  20.707  24.089  1.00 37.37  ? 99  THR D CG2 1 
ATOM   10165 N N   . GLY D 1 100 ? 28.413  19.797  28.719  1.00 45.78  ? 100 GLY D N   1 
ATOM   10166 C CA  . GLY D 1 100 ? 28.589  20.090  30.132  1.00 44.76  ? 100 GLY D CA  1 
ATOM   10167 C C   . GLY D 1 100 ? 28.510  21.566  30.454  1.00 41.69  ? 100 GLY D C   1 
ATOM   10168 O O   . GLY D 1 100 ? 27.470  22.189  30.239  1.00 44.70  ? 100 GLY D O   1 
ATOM   10169 N N   . THR D 1 101 ? 29.608  22.135  30.963  1.00 43.21  ? 101 THR D N   1 
ATOM   10170 C CA  . THR D 1 101 ? 29.677  23.578  31.170  1.00 45.62  ? 101 THR D CA  1 
ATOM   10171 C C   . THR D 1 101 ? 29.577  24.350  29.867  1.00 47.47  ? 101 THR D C   1 
ATOM   10172 O O   . THR D 1 101 ? 29.222  25.533  29.890  1.00 41.34  ? 101 THR D O   1 
ATOM   10173 C CB  . THR D 1 101 ? 30.991  23.981  31.849  1.00 46.88  ? 101 THR D CB  1 
ATOM   10174 O OG1 . THR D 1 101 ? 32.090  23.611  31.007  1.00 47.22  ? 101 THR D OG1 1 
ATOM   10175 C CG2 . THR D 1 101 ? 31.144  23.324  33.223  1.00 43.75  ? 101 THR D CG2 1 
ATOM   10176 N N   . GLY D 1 102 ? 29.910  23.718  28.740  1.00 44.76  ? 102 GLY D N   1 
ATOM   10177 C CA  . GLY D 1 102 ? 30.003  24.415  27.475  1.00 44.01  ? 102 GLY D CA  1 
ATOM   10178 C C   . GLY D 1 102 ? 31.323  25.117  27.215  1.00 42.18  ? 102 GLY D C   1 
ATOM   10179 O O   . GLY D 1 102 ? 31.490  25.697  26.135  1.00 37.42  ? 102 GLY D O   1 
ATOM   10180 N N   . ALA D 1 103 ? 32.260  25.094  28.160  1.00 41.70  ? 103 ALA D N   1 
ATOM   10181 C CA  . ALA D 1 103 ? 33.532  25.766  27.947  1.00 43.93  ? 103 ALA D CA  1 
ATOM   10182 C C   . ALA D 1 103 ? 34.325  25.046  26.863  1.00 40.74  ? 103 ALA D C   1 
ATOM   10183 O O   . ALA D 1 103 ? 34.328  23.818  26.786  1.00 39.11  ? 103 ALA D O   1 
ATOM   10184 C CB  . ALA D 1 103 ? 34.332  25.829  29.246  1.00 40.84  ? 103 ALA D CB  1 
ATOM   10185 N N   . GLY D 1 104 ? 34.984  25.822  26.010  1.00 39.47  ? 104 GLY D N   1 
ATOM   10186 C CA  . GLY D 1 104 ? 35.661  25.269  24.859  1.00 37.37  ? 104 GLY D CA  1 
ATOM   10187 C C   . GLY D 1 104 ? 34.759  24.715  23.775  1.00 39.86  ? 104 GLY D C   1 
ATOM   10188 O O   . GLY D 1 104 ? 35.266  24.188  22.785  1.00 40.09  ? 104 GLY D O   1 
ATOM   10189 N N   . TRP D 1 105 ? 33.449  24.807  23.918  1.00 34.32  ? 105 TRP D N   1 
ATOM   10190 C CA  . TRP D 1 105 ? 32.547  24.250  22.925  1.00 38.31  ? 105 TRP D CA  1 
ATOM   10191 C C   . TRP D 1 105 ? 31.998  25.345  22.016  1.00 34.73  ? 105 TRP D C   1 
ATOM   10192 O O   . TRP D 1 105 ? 32.032  26.535  22.331  1.00 37.24  ? 105 TRP D O   1 
ATOM   10193 C CB  . TRP D 1 105 ? 31.394  23.498  23.598  1.00 35.65  ? 105 TRP D CB  1 
ATOM   10194 C CG  . TRP D 1 105 ? 31.791  22.138  24.092  1.00 38.10  ? 105 TRP D CG  1 
ATOM   10195 C CD1 . TRP D 1 105 ? 32.306  21.831  25.314  1.00 36.31  ? 105 TRP D CD1 1 
ATOM   10196 C CD2 . TRP D 1 105 ? 31.720  20.900  23.364  1.00 40.20  ? 105 TRP D CD2 1 
ATOM   10197 N NE1 . TRP D 1 105 ? 32.543  20.481  25.400  1.00 39.22  ? 105 TRP D NE1 1 
ATOM   10198 C CE2 . TRP D 1 105 ? 32.198  19.888  24.217  1.00 35.82  ? 105 TRP D CE2 1 
ATOM   10199 C CE3 . TRP D 1 105 ? 31.295  20.552  22.074  1.00 36.87  ? 105 TRP D CE3 1 
ATOM   10200 C CZ2 . TRP D 1 105 ? 32.262  18.555  23.828  1.00 35.27  ? 105 TRP D CZ2 1 
ATOM   10201 C CZ3 . TRP D 1 105 ? 31.359  19.231  21.691  1.00 35.13  ? 105 TRP D CZ3 1 
ATOM   10202 C CH2 . TRP D 1 105 ? 31.842  18.247  22.564  1.00 39.02  ? 105 TRP D CH2 1 
ATOM   10203 N N   . SER D 1 106 ? 31.477  24.917  20.875  1.00 34.70  ? 106 SER D N   1 
ATOM   10204 C CA  . SER D 1 106 ? 30.879  25.849  19.940  1.00 31.70  ? 106 SER D CA  1 
ATOM   10205 C C   . SER D 1 106 ? 29.893  25.093  19.068  1.00 29.26  ? 106 SER D C   1 
ATOM   10206 O O   . SER D 1 106 ? 30.014  23.878  18.881  1.00 29.53  ? 106 SER D O   1 
ATOM   10207 C CB  . SER D 1 106 ? 31.948  26.509  19.081  1.00 31.06  ? 106 SER D CB  1 
ATOM   10208 O OG  . SER D 1 106 ? 32.638  25.505  18.378  1.00 27.87  ? 106 SER D OG  1 
ATOM   10209 N N   . LEU D 1 107 ? 28.925  25.830  18.517  1.00 26.86  ? 107 LEU D N   1 
ATOM   10210 C CA  . LEU D 1 107 ? 27.998  25.262  17.543  1.00 26.76  ? 107 LEU D CA  1 
ATOM   10211 C C   . LEU D 1 107 ? 28.544  25.483  16.140  1.00 27.00  ? 107 LEU D C   1 
ATOM   10212 O O   . LEU D 1 107 ? 28.979  26.589  15.809  1.00 28.19  ? 107 LEU D O   1 
ATOM   10213 C CB  . LEU D 1 107 ? 26.613  25.900  17.668  1.00 26.36  ? 107 LEU D CB  1 
ATOM   10214 C CG  . LEU D 1 107 ? 25.451  25.239  16.930  1.00 21.51  ? 107 LEU D CG  1 
ATOM   10215 C CD1 . LEU D 1 107 ? 25.398  23.757  17.186  1.00 28.15  ? 107 LEU D CD1 1 
ATOM   10216 C CD2 . LEU D 1 107 ? 24.173  25.864  17.396  1.00 25.96  ? 107 LEU D CD2 1 
ATOM   10217 N N   . PHE D 1 108 ? 28.505  24.439  15.306  1.00 29.93  ? 108 PHE D N   1 
ATOM   10218 C CA  . PHE D 1 108 ? 28.971  24.512  13.922  1.00 24.56  ? 108 PHE D CA  1 
ATOM   10219 C C   . PHE D 1 108 ? 27.761  24.240  13.028  1.00 30.66  ? 108 PHE D C   1 
ATOM   10220 O O   . PHE D 1 108 ? 27.619  23.134  12.471  1.00 23.63  ? 108 PHE D O   1 
ATOM   10221 C CB  . PHE D 1 108 ? 30.117  23.533  13.681  1.00 24.13  ? 108 PHE D CB  1 
ATOM   10222 C CG  . PHE D 1 108 ? 30.801  23.687  12.339  1.00 26.89  ? 108 PHE D CG  1 
ATOM   10223 C CD1 . PHE D 1 108 ? 31.624  24.764  12.083  1.00 27.99  ? 108 PHE D CD1 1 
ATOM   10224 C CD2 . PHE D 1 108 ? 30.653  22.721  11.350  1.00 27.00  ? 108 PHE D CD2 1 
ATOM   10225 C CE1 . PHE D 1 108 ? 32.264  24.894  10.866  1.00 28.19  ? 108 PHE D CE1 1 
ATOM   10226 C CE2 . PHE D 1 108 ? 31.283  22.857  10.124  1.00 23.44  ? 108 PHE D CE2 1 
ATOM   10227 C CZ  . PHE D 1 108 ? 32.088  23.943  9.882   1.00 23.94  ? 108 PHE D CZ  1 
ATOM   10228 N N   . PRO D 1 109 ? 26.869  25.225  12.865  1.00 28.70  ? 109 PRO D N   1 
ATOM   10229 C CA  . PRO D 1 109 ? 25.617  24.998  12.135  1.00 24.54  ? 109 PRO D CA  1 
ATOM   10230 C C   . PRO D 1 109 ? 25.798  25.221  10.647  1.00 25.50  ? 109 PRO D C   1 
ATOM   10231 O O   . PRO D 1 109 ? 26.605  26.036  10.209  1.00 26.19  ? 109 PRO D O   1 
ATOM   10232 C CB  . PRO D 1 109 ? 24.677  26.059  12.722  1.00 23.19  ? 109 PRO D CB  1 
ATOM   10233 C CG  . PRO D 1 109 ? 25.582  27.197  13.024  1.00 22.09  ? 109 PRO D CG  1 
ATOM   10234 C CD  . PRO D 1 109 ? 26.942  26.597  13.399  1.00 21.26  ? 109 PRO D CD  1 
ATOM   10235 N N   . CYS D 1 110 ? 25.034  24.455  9.873   1.00 24.74  ? 110 CYS D N   1 
ATOM   10236 C CA  . CYS D 1 110 ? 24.971  24.669  8.436   1.00 23.09  ? 110 CYS D CA  1 
ATOM   10237 C C   . CYS D 1 110 ? 24.299  26.000  8.119   1.00 26.77  ? 110 CYS D C   1 
ATOM   10238 O O   . CYS D 1 110 ? 24.837  26.827  7.371   1.00 24.73  ? 110 CYS D O   1 
ATOM   10239 C CB  . CYS D 1 110 ? 24.223  23.509  7.787   1.00 25.17  ? 110 CYS D CB  1 
ATOM   10240 S SG  . CYS D 1 110 ? 24.161  23.558  5.987   1.00 34.37  ? 110 CYS D SG  1 
ATOM   10241 N N   . VAL D 1 111 ? 23.131  26.219  8.705   1.00 25.24  ? 111 VAL D N   1 
ATOM   10242 C CA  . VAL D 1 111 ? 22.310  27.403  8.527   1.00 24.10  ? 111 VAL D CA  1 
ATOM   10243 C C   . VAL D 1 111 ? 22.234  28.089  9.888   1.00 28.70  ? 111 VAL D C   1 
ATOM   10244 O O   . VAL D 1 111 ? 21.792  27.473  10.864  1.00 31.80  ? 111 VAL D O   1 
ATOM   10245 C CB  . VAL D 1 111 ? 20.910  27.022  8.012   1.00 25.32  ? 111 VAL D CB  1 
ATOM   10246 C CG1 . VAL D 1 111 ? 20.114  28.238  7.619   1.00 23.32  ? 111 VAL D CG1 1 
ATOM   10247 C CG2 . VAL D 1 111 ? 21.020  26.072  6.832   1.00 24.15  ? 111 VAL D CG2 1 
ATOM   10248 N N   . SER D 1 112 ? 22.680  29.350  9.967   1.00 25.09  ? 112 SER D N   1 
ATOM   10249 C CA  . SER D 1 112 ? 22.666  30.099  11.230  1.00 25.47  ? 112 SER D CA  1 
ATOM   10250 C C   . SER D 1 112 ? 21.263  30.656  11.481  1.00 32.77  ? 112 SER D C   1 
ATOM   10251 O O   . SER D 1 112 ? 20.979  31.846  11.299  1.00 29.41  ? 112 SER D O   1 
ATOM   10252 C CB  . SER D 1 112 ? 23.705  31.219  11.220  1.00 24.27  ? 112 SER D CB  1 
ATOM   10253 O OG  . SER D 1 112 ? 25.035  30.743  11.035  1.00 27.76  ? 112 SER D OG  1 
ATOM   10254 N N   . THR D 1 113 ? 20.368  29.782  11.931  1.00 24.70  ? 113 THR D N   1 
ATOM   10255 C CA  . THR D 1 113 ? 18.993  30.195  12.163  1.00 25.23  ? 113 THR D CA  1 
ATOM   10256 C C   . THR D 1 113 ? 18.827  30.787  13.551  1.00 28.46  ? 113 THR D C   1 
ATOM   10257 O O   . THR D 1 113 ? 19.716  30.703  14.408  1.00 26.52  ? 113 THR D O   1 
ATOM   10258 C CB  . THR D 1 113 ? 18.026  29.021  12.022  1.00 30.22  ? 113 THR D CB  1 
ATOM   10259 O OG1 . THR D 1 113 ? 18.303  28.056  13.046  1.00 28.89  ? 113 THR D OG1 1 
ATOM   10260 C CG2 . THR D 1 113 ? 18.172  28.359  10.674  1.00 31.22  ? 113 THR D CG2 1 
ATOM   10261 N N   . ARG D 1 114 ? 17.640  31.371  13.771  1.00 27.01  ? 114 ARG D N   1 
ATOM   10262 C CA  . ARG D 1 114 ? 17.252  31.857  15.095  1.00 25.66  ? 114 ARG D CA  1 
ATOM   10263 C C   . ARG D 1 114 ? 17.341  30.757  16.153  1.00 23.09  ? 114 ARG D C   1 
ATOM   10264 O O   . ARG D 1 114 ? 17.830  30.985  17.262  1.00 25.34  ? 114 ARG D O   1 
ATOM   10265 C CB  . ARG D 1 114 ? 15.831  32.420  15.040  1.00 26.31  ? 114 ARG D CB  1 
ATOM   10266 C CG  . ARG D 1 114 ? 15.224  32.706  16.394  1.00 28.89  ? 114 ARG D CG  1 
ATOM   10267 C CD  . ARG D 1 114 ? 13.890  33.458  16.268  1.00 27.26  ? 114 ARG D CD  1 
ATOM   10268 N NE  . ARG D 1 114 ? 13.270  33.643  17.571  1.00 23.58  ? 114 ARG D NE  1 
ATOM   10269 C CZ  . ARG D 1 114 ? 13.475  34.698  18.346  1.00 29.23  ? 114 ARG D CZ  1 
ATOM   10270 N NH1 . ARG D 1 114 ? 14.290  35.675  17.980  1.00 27.58  ? 114 ARG D NH1 1 
ATOM   10271 N NH2 . ARG D 1 114 ? 12.842  34.781  19.515  1.00 29.48  ? 114 ARG D NH2 1 
ATOM   10272 N N   . ALA D 1 115 ? 16.839  29.565  15.846  1.00 25.09  ? 115 ALA D N   1 
ATOM   10273 C CA  . ALA D 1 115 ? 16.948  28.477  16.814  1.00 28.84  ? 115 ALA D CA  1 
ATOM   10274 C C   . ALA D 1 115 ? 18.395  28.036  17.018  1.00 27.66  ? 115 ALA D C   1 
ATOM   10275 O O   . ALA D 1 115 ? 18.770  27.652  18.129  1.00 26.23  ? 115 ALA D O   1 
ATOM   10276 C CB  . ALA D 1 115 ? 16.094  27.291  16.383  1.00 27.66  ? 115 ALA D CB  1 
ATOM   10277 N N   . ALA D 1 116 ? 19.219  28.071  15.971  1.00 26.58  ? 116 ALA D N   1 
ATOM   10278 C CA  . ALA D 1 116 ? 20.622  27.708  16.158  1.00 27.81  ? 116 ALA D CA  1 
ATOM   10279 C C   . ALA D 1 116 ? 21.307  28.681  17.099  1.00 26.40  ? 116 ALA D C   1 
ATOM   10280 O O   . ALA D 1 116 ? 22.186  28.291  17.878  1.00 24.47  ? 116 ALA D O   1 
ATOM   10281 C CB  . ALA D 1 116 ? 21.355  27.664  14.820  1.00 19.98  ? 116 ALA D CB  1 
ATOM   10282 N N   . ALA D 1 117 ? 20.916  29.956  17.039  1.00 29.43  ? 117 ALA D N   1 
ATOM   10283 C CA  . ALA D 1 117 ? 21.470  30.944  17.959  1.00 26.83  ? 117 ALA D CA  1 
ATOM   10284 C C   . ALA D 1 117 ? 20.946  30.720  19.369  1.00 26.94  ? 117 ALA D C   1 
ATOM   10285 O O   . ALA D 1 117 ? 21.709  30.772  20.339  1.00 30.30  ? 117 ALA D O   1 
ATOM   10286 C CB  . ALA D 1 117 ? 21.146  32.358  17.478  1.00 23.56  ? 117 ALA D CB  1 
ATOM   10287 N N   . GLN D 1 118 ? 19.641  30.478  19.506  1.00 28.42  ? 118 GLN D N   1 
ATOM   10288 C CA  . GLN D 1 118 ? 19.101  30.171  20.825  1.00 28.18  ? 118 GLN D CA  1 
ATOM   10289 C C   . GLN D 1 118 ? 19.777  28.937  21.402  1.00 31.18  ? 118 GLN D C   1 
ATOM   10290 O O   . GLN D 1 118 ? 20.154  28.922  22.580  1.00 32.87  ? 118 GLN D O   1 
ATOM   10291 C CB  . GLN D 1 118 ? 17.589  29.991  20.746  1.00 29.66  ? 118 GLN D CB  1 
ATOM   10292 C CG  . GLN D 1 118 ? 16.853  31.307  20.494  1.00 23.88  ? 118 GLN D CG  1 
ATOM   10293 C CD  . GLN D 1 118 ? 15.402  31.098  20.109  1.00 26.99  ? 118 GLN D CD  1 
ATOM   10294 O OE1 . GLN D 1 118 ? 15.086  30.254  19.281  1.00 29.44  ? 118 GLN D OE1 1 
ATOM   10295 N NE2 . GLN D 1 118 ? 14.515  31.901  20.683  1.00 31.75  ? 118 GLN D NE2 1 
ATOM   10296 N N   . LEU D 1 119 ? 20.000  27.920  20.564  1.00 27.50  ? 119 LEU D N   1 
ATOM   10297 C CA  . LEU D 1 119 ? 20.672  26.705  21.019  1.00 28.10  ? 119 LEU D CA  1 
ATOM   10298 C C   . LEU D 1 119 ? 22.028  27.006  21.665  1.00 30.55  ? 119 LEU D C   1 
ATOM   10299 O O   . LEU D 1 119 ? 22.372  26.404  22.685  1.00 33.48  ? 119 LEU D O   1 
ATOM   10300 C CB  . LEU D 1 119 ? 20.836  25.725  19.853  1.00 29.09  ? 119 LEU D CB  1 
ATOM   10301 C CG  . LEU D 1 119 ? 21.431  24.329  20.130  1.00 25.69  ? 119 LEU D CG  1 
ATOM   10302 C CD1 . LEU D 1 119 ? 20.668  23.652  21.239  1.00 26.49  ? 119 LEU D CD1 1 
ATOM   10303 C CD2 . LEU D 1 119 ? 21.408  23.464  18.878  1.00 25.45  ? 119 LEU D CD2 1 
ATOM   10304 N N   . THR D 1 120 ? 22.813  27.934  21.103  1.00 27.56  ? 120 THR D N   1 
ATOM   10305 C CA  . THR D 1 120 ? 24.107  28.217  21.721  1.00 32.35  ? 120 THR D CA  1 
ATOM   10306 C C   . THR D 1 120 ? 23.948  28.848  23.101  1.00 31.30  ? 120 THR D C   1 
ATOM   10307 O O   . THR D 1 120 ? 24.799  28.636  23.968  1.00 32.55  ? 120 THR D O   1 
ATOM   10308 C CB  . THR D 1 120 ? 24.976  29.138  20.851  1.00 32.43  ? 120 THR D CB  1 
ATOM   10309 O OG1 . THR D 1 120 ? 24.414  30.452  20.810  1.00 25.95  ? 120 THR D OG1 1 
ATOM   10310 C CG2 . THR D 1 120 ? 25.146  28.597  19.434  1.00 24.89  ? 120 THR D CG2 1 
ATOM   10311 N N   . ARG D 1 121 ? 22.891  29.635  23.324  1.00 28.93  ? 121 ARG D N   1 
ATOM   10312 C CA  . ARG D 1 121 ? 22.702  30.198  24.659  1.00 33.30  ? 121 ARG D CA  1 
ATOM   10313 C C   . ARG D 1 121 ? 22.177  29.149  25.636  1.00 34.41  ? 121 ARG D C   1 
ATOM   10314 O O   . ARG D 1 121 ? 22.586  29.132  26.802  1.00 40.21  ? 121 ARG D O   1 
ATOM   10315 C CB  . ARG D 1 121 ? 21.767  31.411  24.610  1.00 35.24  ? 121 ARG D CB  1 
ATOM   10316 C CG  . ARG D 1 121 ? 22.523  32.756  24.566  1.00 42.82  ? 121 ARG D CG  1 
ATOM   10317 C CD  . ARG D 1 121 ? 21.927  33.790  25.503  1.00 39.78  ? 121 ARG D CD  1 
ATOM   10318 N NE  . ARG D 1 121 ? 22.257  35.155  25.106  1.00 45.04  ? 121 ARG D NE  1 
ATOM   10319 C CZ  . ARG D 1 121 ? 21.387  36.160  25.113  1.00 52.93  ? 121 ARG D CZ  1 
ATOM   10320 N NH1 . ARG D 1 121 ? 20.121  35.976  25.458  1.00 48.84  ? 121 ARG D NH1 1 
ATOM   10321 N NH2 . ARG D 1 121 ? 21.794  37.378  24.762  1.00 52.55  ? 121 ARG D NH2 1 
ATOM   10322 N N   . LYS D 1 122 ? 21.291  28.256  25.178  1.00 30.32  ? 122 LYS D N   1 
ATOM   10323 C CA  . LYS D 1 122 ? 20.803  27.176  26.038  1.00 38.19  ? 122 LYS D CA  1 
ATOM   10324 C C   . LYS D 1 122 ? 21.942  26.279  26.511  1.00 38.60  ? 122 LYS D C   1 
ATOM   10325 O O   . LYS D 1 122 ? 21.939  25.807  27.652  1.00 34.82  ? 122 LYS D O   1 
ATOM   10326 C CB  . LYS D 1 122 ? 19.758  26.341  25.297  1.00 31.85  ? 122 LYS D CB  1 
ATOM   10327 C CG  . LYS D 1 122 ? 18.342  26.685  25.652  1.00 40.79  ? 122 LYS D CG  1 
ATOM   10328 C CD  . LYS D 1 122 ? 17.776  27.686  24.672  1.00 39.72  ? 122 LYS D CD  1 
ATOM   10329 C CE  . LYS D 1 122 ? 16.299  27.884  24.914  1.00 48.78  ? 122 LYS D CE  1 
ATOM   10330 N NZ  . LYS D 1 122 ? 16.036  27.981  26.379  1.00 53.01  ? 122 LYS D NZ  1 
ATOM   10331 N N   . LEU D 1 123 ? 22.921  26.025  25.650  1.00 36.60  ? 123 LEU D N   1 
ATOM   10332 C CA  . LEU D 1 123 ? 24.010  25.134  26.004  1.00 35.68  ? 123 LEU D CA  1 
ATOM   10333 C C   . LEU D 1 123 ? 25.160  25.842  26.715  1.00 36.84  ? 123 LEU D C   1 
ATOM   10334 O O   . LEU D 1 123 ? 26.039  25.161  27.248  1.00 40.53  ? 123 LEU D O   1 
ATOM   10335 C CB  . LEU D 1 123 ? 24.513  24.415  24.747  1.00 31.79  ? 123 LEU D CB  1 
ATOM   10336 C CG  . LEU D 1 123 ? 23.523  23.423  24.112  1.00 33.60  ? 123 LEU D CG  1 
ATOM   10337 C CD1 . LEU D 1 123 ? 24.097  22.761  22.846  1.00 27.72  ? 123 LEU D CD1 1 
ATOM   10338 C CD2 . LEU D 1 123 ? 23.099  22.353  25.112  1.00 34.91  ? 123 LEU D CD2 1 
ATOM   10339 N N   . ASN D 1 124 ? 25.164  27.179  26.764  1.00 37.39  ? 124 ASN D N   1 
ATOM   10340 C CA  . ASN D 1 124 ? 26.291  27.963  27.301  1.00 42.26  ? 124 ASN D CA  1 
ATOM   10341 C C   . ASN D 1 124 ? 27.599  27.682  26.561  1.00 42.50  ? 124 ASN D C   1 
ATOM   10342 O O   . ASN D 1 124 ? 28.693  27.771  27.138  1.00 41.30  ? 124 ASN D O   1 
ATOM   10343 C CB  . ASN D 1 124 ? 26.496  27.736  28.807  1.00 43.11  ? 124 ASN D CB  1 
ATOM   10344 C CG  . ASN D 1 124 ? 25.341  28.250  29.635  1.00 44.02  ? 124 ASN D CG  1 
ATOM   10345 O OD1 . ASN D 1 124 ? 24.735  27.501  30.411  1.00 46.37  ? 124 ASN D OD1 1 
ATOM   10346 N ND2 . ASN D 1 124 ? 25.001  29.523  29.452  1.00 47.29  ? 124 ASN D ND2 1 
ATOM   10347 N N   . VAL D 1 125 ? 27.516  27.340  25.280  1.00 39.26  ? 125 VAL D N   1 
ATOM   10348 C CA  . VAL D 1 125 ? 28.732  27.192  24.495  1.00 34.26  ? 125 VAL D CA  1 
ATOM   10349 C C   . VAL D 1 125 ? 29.004  28.562  23.904  1.00 36.34  ? 125 VAL D C   1 
ATOM   10350 O O   . VAL D 1 125 ? 28.208  29.485  24.113  1.00 33.98  ? 125 VAL D O   1 
ATOM   10351 C CB  . VAL D 1 125 ? 28.585  26.109  23.418  1.00 38.51  ? 125 VAL D CB  1 
ATOM   10352 C CG1 . VAL D 1 125 ? 28.023  24.838  24.046  1.00 33.02  ? 125 VAL D CG1 1 
ATOM   10353 C CG2 . VAL D 1 125 ? 27.682  26.602  22.291  1.00 35.58  ? 125 VAL D CG2 1 
ATOM   10354 N N   . ALA D 1 126 ? 30.134  28.717  23.204  1.00 35.34  ? 126 ALA D N   1 
ATOM   10355 C CA  . ALA D 1 126 ? 30.437  29.972  22.528  1.00 28.48  ? 126 ALA D CA  1 
ATOM   10356 C C   . ALA D 1 126 ? 29.209  30.494  21.803  1.00 26.24  ? 126 ALA D C   1 
ATOM   10357 O O   . ALA D 1 126 ? 28.509  29.744  21.118  1.00 31.44  ? 126 ALA D O   1 
ATOM   10358 C CB  . ALA D 1 126 ? 31.581  29.780  21.533  1.00 33.89  ? 126 ALA D CB  1 
ATOM   10359 N N   . ALA D 1 127 ? 28.921  31.774  21.999  1.00 33.04  ? 127 ALA D N   1 
ATOM   10360 C CA  . ALA D 1 127 ? 27.774  32.373  21.340  1.00 28.57  ? 127 ALA D CA  1 
ATOM   10361 C C   . ALA D 1 127 ? 27.973  32.317  19.832  1.00 24.95  ? 127 ALA D C   1 
ATOM   10362 O O   . ALA D 1 127 ? 29.063  32.595  19.330  1.00 28.58  ? 127 ALA D O   1 
ATOM   10363 C CB  . ALA D 1 127 ? 27.601  33.811  21.807  1.00 27.57  ? 127 ALA D CB  1 
ATOM   10364 N N   . LEU D 1 128 ? 26.928  31.914  19.114  1.00 28.96  ? 128 LEU D N   1 
ATOM   10365 C CA  . LEU D 1 128 ? 26.975  31.904  17.657  1.00 26.51  ? 128 LEU D CA  1 
ATOM   10366 C C   . LEU D 1 128 ? 27.458  33.251  17.141  1.00 28.63  ? 128 LEU D C   1 
ATOM   10367 O O   . LEU D 1 128 ? 26.986  34.306  17.583  1.00 28.02  ? 128 LEU D O   1 
ATOM   10368 C CB  . LEU D 1 128 ? 25.595  31.581  17.087  1.00 24.92  ? 128 LEU D CB  1 
ATOM   10369 C CG  . LEU D 1 128 ? 25.641  30.910  15.714  1.00 24.92  ? 128 LEU D CG  1 
ATOM   10370 C CD1 . LEU D 1 128 ? 26.166  29.506  15.826  1.00 25.93  ? 128 LEU D CD1 1 
ATOM   10371 C CD2 . LEU D 1 128 ? 24.296  30.906  15.070  1.00 27.66  ? 128 LEU D CD2 1 
ATOM   10372 N N   . ASP D 1 129 ? 28.447  33.224  16.254  1.00 22.83  ? 129 ASP D N   1 
ATOM   10373 C CA  . ASP D 1 129 ? 28.898  34.485  15.686  1.00 26.71  ? 129 ASP D CA  1 
ATOM   10374 C C   . ASP D 1 129 ? 27.744  35.102  14.904  1.00 24.84  ? 129 ASP D C   1 
ATOM   10375 O O   . ASP D 1 129 ? 27.015  34.398  14.200  1.00 21.27  ? 129 ASP D O   1 
ATOM   10376 C CB  . ASP D 1 129 ? 30.125  34.280  14.798  1.00 25.39  ? 129 ASP D CB  1 
ATOM   10377 C CG  . ASP D 1 129 ? 30.913  35.569  14.586  1.00 25.62  ? 129 ASP D CG  1 
ATOM   10378 O OD1 . ASP D 1 129 ? 30.623  36.577  15.256  1.00 35.35  ? 129 ASP D OD1 1 
ATOM   10379 O OD2 . ASP D 1 129 ? 31.843  35.587  13.769  1.00 23.82  ? 129 ASP D OD2 1 
ATOM   10380 N N   . GLY D 1 130 ? 27.544  36.408  15.080  1.00 22.62  ? 130 GLY D N   1 
ATOM   10381 C CA  . GLY D 1 130 ? 26.392  37.078  14.490  1.00 24.79  ? 130 GLY D CA  1 
ATOM   10382 C C   . GLY D 1 130 ? 25.080  36.697  15.140  1.00 24.59  ? 130 GLY D C   1 
ATOM   10383 O O   . GLY D 1 130 ? 24.052  36.589  14.458  1.00 18.60  ? 130 GLY D O   1 
ATOM   10384 N N   . TYR D 1 131 ? 25.106  36.477  16.453  1.00 26.21  ? 131 TYR D N   1 
ATOM   10385 C CA  . TYR D 1 131 ? 23.946  35.999  17.194  1.00 25.85  ? 131 TYR D CA  1 
ATOM   10386 C C   . TYR D 1 131 ? 22.717  36.872  16.942  1.00 22.98  ? 131 TYR D C   1 
ATOM   10387 O O   . TYR D 1 131 ? 21.644  36.367  16.604  1.00 23.42  ? 131 TYR D O   1 
ATOM   10388 C CB  . TYR D 1 131 ? 24.313  35.949  18.687  1.00 20.16  ? 131 TYR D CB  1 
ATOM   10389 C CG  . TYR D 1 131 ? 23.177  35.695  19.623  1.00 27.84  ? 131 TYR D CG  1 
ATOM   10390 C CD1 . TYR D 1 131 ? 22.825  34.392  19.995  1.00 25.91  ? 131 TYR D CD1 1 
ATOM   10391 C CD2 . TYR D 1 131 ? 22.459  36.761  20.170  1.00 25.27  ? 131 TYR D CD2 1 
ATOM   10392 C CE1 . TYR D 1 131 ? 21.783  34.171  20.865  1.00 26.55  ? 131 TYR D CE1 1 
ATOM   10393 C CE2 . TYR D 1 131 ? 21.424  36.545  21.031  1.00 26.00  ? 131 TYR D CE2 1 
ATOM   10394 C CZ  . TYR D 1 131 ? 21.090  35.254  21.378  1.00 27.29  ? 131 TYR D CZ  1 
ATOM   10395 O OH  . TYR D 1 131 ? 20.051  35.066  22.248  1.00 37.01  ? 131 TYR D OH  1 
ATOM   10396 N N   . GLU D 1 132 ? 22.866  38.189  17.086  1.00 24.44  ? 132 GLU D N   1 
ATOM   10397 C CA  . GLU D 1 132 ? 21.730  39.094  16.934  1.00 24.14  ? 132 GLU D CA  1 
ATOM   10398 C C   . GLU D 1 132 ? 21.151  39.044  15.526  1.00 22.45  ? 132 GLU D C   1 
ATOM   10399 O O   . GLU D 1 132 ? 19.926  39.024  15.349  1.00 21.40  ? 132 GLU D O   1 
ATOM   10400 C CB  . GLU D 1 132 ? 22.149  40.526  17.293  1.00 22.47  ? 132 GLU D CB  1 
ATOM   10401 C CG  . GLU D 1 132 ? 22.516  40.748  18.787  1.00 25.89  ? 132 GLU D CG  1 
ATOM   10402 C CD  . GLU D 1 132 ? 21.445  40.255  19.779  1.00 26.38  ? 132 GLU D CD  1 
ATOM   10403 O OE1 . GLU D 1 132 ? 20.301  39.956  19.363  1.00 30.27  ? 132 GLU D OE1 1 
ATOM   10404 O OE2 . GLU D 1 132 ? 21.752  40.147  20.988  1.00 31.74  ? 132 GLU D OE2 1 
ATOM   10405 N N   . PHE D 1 133 ? 22.012  39.058  14.507  1.00 21.70  ? 133 PHE D N   1 
ATOM   10406 C CA  . PHE D 1 133 ? 21.517  38.930  13.139  1.00 23.46  ? 133 PHE D CA  1 
ATOM   10407 C C   . PHE D 1 133 ? 20.719  37.634  12.968  1.00 26.52  ? 133 PHE D C   1 
ATOM   10408 O O   . PHE D 1 133 ? 19.635  37.634  12.356  1.00 19.74  ? 133 PHE D O   1 
ATOM   10409 C CB  . PHE D 1 133 ? 22.695  39.006  12.163  1.00 24.87  ? 133 PHE D CB  1 
ATOM   10410 C CG  . PHE D 1 133 ? 22.306  39.045  10.709  1.00 26.30  ? 133 PHE D CG  1 
ATOM   10411 C CD1 . PHE D 1 133 ? 21.544  40.082  10.196  1.00 25.35  ? 133 PHE D CD1 1 
ATOM   10412 C CD2 . PHE D 1 133 ? 22.729  38.046  9.846   1.00 24.03  ? 133 PHE D CD2 1 
ATOM   10413 C CE1 . PHE D 1 133 ? 21.232  40.118  8.833   1.00 26.83  ? 133 PHE D CE1 1 
ATOM   10414 C CE2 . PHE D 1 133 ? 22.399  38.065  8.496   1.00 25.34  ? 133 PHE D CE2 1 
ATOM   10415 C CZ  . PHE D 1 133 ? 21.663  39.098  7.986   1.00 22.80  ? 133 PHE D CZ  1 
ATOM   10416 N N   . ALA D 1 134 ? 21.221  36.528  13.531  1.00 20.37  ? 134 ALA D N   1 
ATOM   10417 C CA  . ALA D 1 134 ? 20.484  35.272  13.435  1.00 20.56  ? 134 ALA D CA  1 
ATOM   10418 C C   . ALA D 1 134 ? 19.183  35.330  14.232  1.00 25.40  ? 134 ALA D C   1 
ATOM   10419 O O   . ALA D 1 134 ? 18.162  34.788  13.795  1.00 25.00  ? 134 ALA D O   1 
ATOM   10420 C CB  . ALA D 1 134 ? 21.354  34.104  13.899  1.00 22.10  ? 134 ALA D CB  1 
ATOM   10421 N N   . MET D 1 135 ? 19.188  35.990  15.397  1.00 21.06  ? 135 MET D N   1 
ATOM   10422 C CA  . MET D 1 135 ? 17.955  36.067  16.175  1.00 23.79  ? 135 MET D CA  1 
ATOM   10423 C C   . MET D 1 135 ? 16.846  36.794  15.414  1.00 22.67  ? 135 MET D C   1 
ATOM   10424 O O   . MET D 1 135 ? 15.667  36.521  15.636  1.00 22.05  ? 135 MET D O   1 
ATOM   10425 C CB  . MET D 1 135 ? 18.217  36.737  17.527  1.00 25.97  ? 135 MET D CB  1 
ATOM   10426 C CG  . MET D 1 135 ? 18.992  35.853  18.530  1.00 27.70  ? 135 MET D CG  1 
ATOM   10427 S SD  . MET D 1 135 ? 18.165  34.285  18.965  1.00 30.28  ? 135 MET D SD  1 
ATOM   10428 C CE  . MET D 1 135 ? 17.104  34.867  20.303  1.00 22.96  ? 135 MET D CE  1 
ATOM   10429 N N   . GLN D 1 136 ? 17.183  37.710  14.519  1.00 21.80  ? 136 GLN D N   1 
ATOM   10430 C CA  . GLN D 1 136 ? 16.175  38.330  13.673  1.00 18.92  ? 136 GLN D CA  1 
ATOM   10431 C C   . GLN D 1 136 ? 15.922  37.530  12.402  1.00 26.42  ? 136 GLN D C   1 
ATOM   10432 O O   . GLN D 1 136 ? 15.207  38.005  11.503  1.00 26.53  ? 136 GLN D O   1 
ATOM   10433 C CB  . GLN D 1 136 ? 16.579  39.761  13.344  1.00 18.21  ? 136 GLN D CB  1 
ATOM   10434 C CG  . GLN D 1 136 ? 16.790  40.614  14.606  1.00 22.22  ? 136 GLN D CG  1 
ATOM   10435 C CD  . GLN D 1 136 ? 15.614  40.590  15.562  1.00 21.96  ? 136 GLN D CD  1 
ATOM   10436 O OE1 . GLN D 1 136 ? 14.448  40.749  15.163  1.00 21.27  ? 136 GLN D OE1 1 
ATOM   10437 N NE2 . GLN D 1 136 ? 15.909  40.363  16.832  1.00 22.78  ? 136 GLN D NE2 1 
ATOM   10438 N N   . ASN D 1 137 ? 16.445  36.304  12.343  1.00 24.57  ? 137 ASN D N   1 
ATOM   10439 C CA  . ASN D 1 137 ? 16.402  35.460  11.154  1.00 27.75  ? 137 ASN D CA  1 
ATOM   10440 C C   . ASN D 1 137 ? 16.960  36.220  9.958   1.00 26.34  ? 137 ASN D C   1 
ATOM   10441 O O   . ASN D 1 137 ? 16.344  36.312  8.898   1.00 25.44  ? 137 ASN D O   1 
ATOM   10442 C CB  . ASN D 1 137 ? 14.991  34.926  10.899  1.00 31.29  ? 137 ASN D CB  1 
ATOM   10443 C CG  . ASN D 1 137 ? 14.628  33.760  11.846  1.00 34.31  ? 137 ASN D CG  1 
ATOM   10444 O OD1 . ASN D 1 137 ? 15.391  32.789  11.997  1.00 36.37  ? 137 ASN D OD1 1 
ATOM   10445 N ND2 . ASN D 1 137 ? 13.467  33.855  12.477  1.00 26.15  ? 137 ASN D ND2 1 
ATOM   10446 N N   . GLY D 1 138 ? 18.158  36.777  10.156  1.00 26.12  ? 138 GLY D N   1 
ATOM   10447 C CA  . GLY D 1 138 ? 18.814  37.511  9.089   1.00 21.83  ? 138 GLY D CA  1 
ATOM   10448 C C   . GLY D 1 138 ? 19.090  36.661  7.868   1.00 25.09  ? 138 GLY D C   1 
ATOM   10449 O O   . GLY D 1 138 ? 18.959  37.132  6.737   1.00 23.62  ? 138 GLY D O   1 
ATOM   10450 N N   . ILE D 1 139 ? 19.460  35.391  8.078   1.00 27.79  ? 139 ILE D N   1 
ATOM   10451 C CA  . ILE D 1 139 ? 19.890  34.569  6.955   1.00 29.88  ? 139 ILE D CA  1 
ATOM   10452 C C   . ILE D 1 139 ? 18.729  34.336  5.990   1.00 33.02  ? 139 ILE D C   1 
ATOM   10453 O O   . ILE D 1 139 ? 18.912  34.373  4.764   1.00 30.04  ? 139 ILE D O   1 
ATOM   10454 C CB  . ILE D 1 139 ? 20.523  33.254  7.457   1.00 34.82  ? 139 ILE D CB  1 
ATOM   10455 C CG1 . ILE D 1 139 ? 19.481  32.319  8.058   1.00 39.12  ? 139 ILE D CG1 1 
ATOM   10456 C CG2 . ILE D 1 139 ? 21.593  33.554  8.525   1.00 32.23  ? 139 ILE D CG2 1 
ATOM   10457 C CD1 . ILE D 1 139 ? 18.885  31.334  7.072   1.00 37.75  ? 139 ILE D CD1 1 
ATOM   10458 N N   . ASP D 1 140 ? 17.519  34.130  6.527   1.00 32.64  ? 140 ASP D N   1 
ATOM   10459 C CA  . ASP D 1 140 ? 16.317  34.017  5.704   1.00 28.33  ? 140 ASP D CA  1 
ATOM   10460 C C   . ASP D 1 140 ? 16.275  35.120  4.655   1.00 32.49  ? 140 ASP D C   1 
ATOM   10461 O O   . ASP D 1 140 ? 16.058  34.859  3.464   1.00 34.82  ? 140 ASP D O   1 
ATOM   10462 C CB  . ASP D 1 140 ? 15.070  34.090  6.595   1.00 33.29  ? 140 ASP D CB  1 
ATOM   10463 C CG  . ASP D 1 140 ? 14.520  32.723  6.972   1.00 44.92  ? 140 ASP D CG  1 
ATOM   10464 O OD1 . ASP D 1 140 ? 14.008  32.006  6.071   1.00 49.32  ? 140 ASP D OD1 1 
ATOM   10465 O OD2 . ASP D 1 140 ? 14.553  32.391  8.185   1.00 45.47  ? 140 ASP D OD2 1 
ATOM   10466 N N   . LEU D 1 141 ? 16.510  36.366  5.088   1.00 26.36  ? 141 LEU D N   1 
ATOM   10467 C CA  . LEU D 1 141 ? 16.544  37.504  4.173   1.00 27.42  ? 141 LEU D CA  1 
ATOM   10468 C C   . LEU D 1 141 ? 17.588  37.304  3.079   1.00 27.35  ? 141 LEU D C   1 
ATOM   10469 O O   . LEU D 1 141 ? 17.297  37.454  1.885   1.00 27.61  ? 141 LEU D O   1 
ATOM   10470 C CB  . LEU D 1 141 ? 16.822  38.785  4.959   1.00 25.84  ? 141 LEU D CB  1 
ATOM   10471 C CG  . LEU D 1 141 ? 17.038  40.014  4.083   1.00 31.06  ? 141 LEU D CG  1 
ATOM   10472 C CD1 . LEU D 1 141 ? 15.731  40.368  3.422   1.00 30.73  ? 141 LEU D CD1 1 
ATOM   10473 C CD2 . LEU D 1 141 ? 17.606  41.196  4.854   1.00 20.28  ? 141 LEU D CD2 1 
ATOM   10474 N N   . LEU D 1 142 ? 18.810  36.938  3.468   1.00 27.22  ? 142 LEU D N   1 
ATOM   10475 C CA  . LEU D 1 142 ? 19.916  36.892  2.519   1.00 27.04  ? 142 LEU D CA  1 
ATOM   10476 C C   . LEU D 1 142 ? 19.769  35.761  1.511   1.00 32.08  ? 142 LEU D C   1 
ATOM   10477 O O   . LEU D 1 142 ? 20.333  35.856  0.411   1.00 32.29  ? 142 LEU D O   1 
ATOM   10478 C CB  . LEU D 1 142 ? 21.243  36.777  3.280   1.00 30.01  ? 142 LEU D CB  1 
ATOM   10479 C CG  . LEU D 1 142 ? 21.810  38.090  3.869   1.00 25.30  ? 142 LEU D CG  1 
ATOM   10480 C CD1 . LEU D 1 142 ? 23.189  37.855  4.416   1.00 31.33  ? 142 LEU D CD1 1 
ATOM   10481 C CD2 . LEU D 1 142 ? 21.852  39.221  2.834   1.00 28.93  ? 142 LEU D CD2 1 
ATOM   10482 N N   . ASN D 1 143 ? 19.004  34.716  1.849   1.00 29.40  ? 143 ASN D N   1 
ATOM   10483 C CA  . ASN D 1 143 ? 18.802  33.552  0.997   1.00 32.68  ? 143 ASN D CA  1 
ATOM   10484 C C   . ASN D 1 143 ? 17.618  33.702  0.043   1.00 37.49  ? 143 ASN D C   1 
ATOM   10485 O O   . ASN D 1 143 ? 17.239  32.720  -0.608  1.00 31.33  ? 143 ASN D O   1 
ATOM   10486 C CB  . ASN D 1 143 ? 18.610  32.294  1.857   1.00 28.35  ? 143 ASN D CB  1 
ATOM   10487 C CG  . ASN D 1 143 ? 19.927  31.726  2.361   1.00 34.74  ? 143 ASN D CG  1 
ATOM   10488 O OD1 . ASN D 1 143 ? 20.979  31.929  1.744   1.00 32.28  ? 143 ASN D OD1 1 
ATOM   10489 N ND2 . ASN D 1 143 ? 19.880  31.005  3.481   1.00 34.55  ? 143 ASN D ND2 1 
ATOM   10490 N N   . MET D 1 144 ? 17.012  34.887  -0.048  1.00 28.38  ? 144 MET D N   1 
ATOM   10491 C CA  . MET D 1 144 ? 15.983  35.117  -1.051  1.00 32.22  ? 144 MET D CA  1 
ATOM   10492 C C   . MET D 1 144 ? 16.650  35.629  -2.319  1.00 33.45  ? 144 MET D C   1 
ATOM   10493 O O   . MET D 1 144 ? 17.487  36.545  -2.271  1.00 29.07  ? 144 MET D O   1 
ATOM   10494 C CB  . MET D 1 144 ? 14.909  36.103  -0.571  1.00 35.49  ? 144 MET D CB  1 
ATOM   10495 C CG  . MET D 1 144 ? 14.300  35.798  0.800   1.00 40.01  ? 144 MET D CG  1 
ATOM   10496 S SD  . MET D 1 144 ? 13.387  37.213  1.446   1.00 38.33  ? 144 MET D SD  1 
ATOM   10497 C CE  . MET D 1 144 ? 13.092  36.727  3.157   1.00 41.65  ? 144 MET D CE  1 
ATOM   10498 N N   . LYS D 1 145 ? 16.293  35.014  -3.449  1.00 30.44  ? 145 LYS D N   1 
ATOM   10499 C CA  . LYS D 1 145 ? 16.839  35.433  -4.734  1.00 28.55  ? 145 LYS D CA  1 
ATOM   10500 C C   . LYS D 1 145 ? 16.652  36.935  -4.950  1.00 24.16  ? 145 LYS D C   1 
ATOM   10501 O O   . LYS D 1 145 ? 17.566  37.625  -5.418  1.00 27.22  ? 145 LYS D O   1 
ATOM   10502 C CB  . LYS D 1 145 ? 16.170  34.634  -5.858  1.00 27.10  ? 145 LYS D CB  1 
ATOM   10503 C CG  . LYS D 1 145 ? 16.981  33.506  -6.406  1.00 33.51  ? 145 LYS D CG  1 
ATOM   10504 C CD  . LYS D 1 145 ? 17.194  32.458  -5.377  1.00 36.47  ? 145 LYS D CD  1 
ATOM   10505 C CE  . LYS D 1 145 ? 16.896  31.105  -5.961  1.00 40.52  ? 145 LYS D CE  1 
ATOM   10506 N NZ  . LYS D 1 145 ? 16.237  30.295  -4.927  1.00 39.79  ? 145 LYS D NZ  1 
ATOM   10507 N N   . SER D 1 146 ? 15.480  37.459  -4.589  1.00 24.32  ? 146 SER D N   1 
ATOM   10508 C CA  . SER D 1 146 ? 15.194  38.877  -4.778  1.00 25.61  ? 146 SER D CA  1 
ATOM   10509 C C   . SER D 1 146 ? 16.144  39.776  -3.992  1.00 26.54  ? 146 SER D C   1 
ATOM   10510 O O   . SER D 1 146 ? 16.451  40.890  -4.445  1.00 26.57  ? 146 SER D O   1 
ATOM   10511 C CB  . SER D 1 146 ? 13.747  39.182  -4.386  1.00 28.04  ? 146 SER D CB  1 
ATOM   10512 O OG  . SER D 1 146 ? 13.416  38.683  -3.094  1.00 28.30  ? 146 SER D OG  1 
ATOM   10513 N N   . THR D 1 147 ? 16.584  39.351  -2.801  1.00 23.02  ? 147 THR D N   1 
ATOM   10514 C CA  . THR D 1 147 ? 17.536  40.170  -2.057  1.00 22.45  ? 147 THR D CA  1 
ATOM   10515 C C   . THR D 1 147 ? 18.854  40.261  -2.808  1.00 22.11  ? 147 THR D C   1 
ATOM   10516 O O   . THR D 1 147 ? 19.463  41.331  -2.888  1.00 20.32  ? 147 THR D O   1 
ATOM   10517 C CB  . THR D 1 147 ? 17.787  39.611  -0.653  1.00 26.78  ? 147 THR D CB  1 
ATOM   10518 O OG1 . THR D 1 147 ? 16.555  39.493  0.069   1.00 27.24  ? 147 THR D OG1 1 
ATOM   10519 C CG2 . THR D 1 147 ? 18.722  40.529  0.131   1.00 24.39  ? 147 THR D CG2 1 
ATOM   10520 N N   . PHE D 1 148 ? 19.305  39.142  -3.374  1.00 25.78  ? 148 PHE D N   1 
ATOM   10521 C CA  . PHE D 1 148 ? 20.540  39.151  -4.143  1.00 25.39  ? 148 PHE D CA  1 
ATOM   10522 C C   . PHE D 1 148 ? 20.471  40.166  -5.275  1.00 23.29  ? 148 PHE D C   1 
ATOM   10523 O O   . PHE D 1 148 ? 21.341  41.035  -5.409  1.00 25.98  ? 148 PHE D O   1 
ATOM   10524 C CB  . PHE D 1 148 ? 20.837  37.762  -4.709  1.00 24.04  ? 148 PHE D CB  1 
ATOM   10525 C CG  . PHE D 1 148 ? 22.003  37.767  -5.609  1.00 22.92  ? 148 PHE D CG  1 
ATOM   10526 C CD1 . PHE D 1 148 ? 23.279  37.896  -5.087  1.00 25.25  ? 148 PHE D CD1 1 
ATOM   10527 C CD2 . PHE D 1 148 ? 21.833  37.769  -6.983  1.00 31.96  ? 148 PHE D CD2 1 
ATOM   10528 C CE1 . PHE D 1 148 ? 24.362  37.964  -5.916  1.00 27.41  ? 148 PHE D CE1 1 
ATOM   10529 C CE2 . PHE D 1 148 ? 22.919  37.825  -7.832  1.00 30.30  ? 148 PHE D CE2 1 
ATOM   10530 C CZ  . PHE D 1 148 ? 24.184  37.924  -7.302  1.00 31.41  ? 148 PHE D CZ  1 
ATOM   10531 N N   . ARG D 1 149 ? 19.441  40.056  -6.117  1.00 22.30  ? 149 ARG D N   1 
ATOM   10532 C CA  . ARG D 1 149 ? 19.293  40.991  -7.219  1.00 22.07  ? 149 ARG D CA  1 
ATOM   10533 C C   . ARG D 1 149 ? 19.249  42.427  -6.714  1.00 23.51  ? 149 ARG D C   1 
ATOM   10534 O O   . ARG D 1 149 ? 19.824  43.328  -7.333  1.00 22.48  ? 149 ARG D O   1 
ATOM   10535 C CB  . ARG D 1 149 ? 18.035  40.663  -8.013  1.00 22.23  ? 149 ARG D CB  1 
ATOM   10536 C CG  . ARG D 1 149 ? 18.132  39.391  -8.841  1.00 25.59  ? 149 ARG D CG  1 
ATOM   10537 C CD  . ARG D 1 149 ? 17.081  39.364  -9.949  1.00 30.99  ? 149 ARG D CD  1 
ATOM   10538 N NE  . ARG D 1 149 ? 17.249  40.513  -10.838 1.00 28.59  ? 149 ARG D NE  1 
ATOM   10539 C CZ  . ARG D 1 149 ? 18.070  40.526  -11.877 1.00 29.42  ? 149 ARG D CZ  1 
ATOM   10540 N NH1 . ARG D 1 149 ? 18.727  39.435  -12.254 1.00 26.77  ? 149 ARG D NH1 1 
ATOM   10541 N NH2 . ARG D 1 149 ? 18.231  41.655  -12.556 1.00 27.72  ? 149 ARG D NH2 1 
ATOM   10542 N N   . ARG D 1 150 ? 18.589  42.660  -5.582  1.00 22.48  ? 150 ARG D N   1 
ATOM   10543 C CA  . ARG D 1 150 ? 18.482  44.025  -5.065  1.00 26.70  ? 150 ARG D CA  1 
ATOM   10544 C C   . ARG D 1 150 ? 19.834  44.538  -4.609  1.00 25.15  ? 150 ARG D C   1 
ATOM   10545 O O   . ARG D 1 150 ? 20.279  45.611  -5.036  1.00 23.47  ? 150 ARG D O   1 
ATOM   10546 C CB  . ARG D 1 150 ? 17.487  44.088  -3.912  1.00 21.74  ? 150 ARG D CB  1 
ATOM   10547 C CG  . ARG D 1 150 ? 16.083  44.296  -4.368  1.00 26.54  ? 150 ARG D CG  1 
ATOM   10548 C CD  . ARG D 1 150 ? 15.115  43.575  -3.472  1.00 24.75  ? 150 ARG D CD  1 
ATOM   10549 N NE  . ARG D 1 150 ? 13.751  43.740  -3.953  1.00 23.21  ? 150 ARG D NE  1 
ATOM   10550 C CZ  . ARG D 1 150 ? 12.688  43.347  -3.270  1.00 29.53  ? 150 ARG D CZ  1 
ATOM   10551 N NH1 . ARG D 1 150 ? 12.811  42.760  -2.093  1.00 24.21  ? 150 ARG D NH1 1 
ATOM   10552 N NH2 . ARG D 1 150 ? 11.473  43.547  -3.779  1.00 30.14  ? 150 ARG D NH2 1 
ATOM   10553 N N   . LEU D 1 151 ? 20.498  43.779  -3.732  1.00 24.99  ? 151 LEU D N   1 
ATOM   10554 C CA  . LEU D 1 151 ? 21.830  44.156  -3.271  1.00 25.88  ? 151 LEU D CA  1 
ATOM   10555 C C   . LEU D 1 151 ? 22.778  44.295  -4.449  1.00 26.05  ? 151 LEU D C   1 
ATOM   10556 O O   . LEU D 1 151 ? 23.541  45.265  -4.544  1.00 24.91  ? 151 LEU D O   1 
ATOM   10557 C CB  . LEU D 1 151 ? 22.357  43.113  -2.288  1.00 22.01  ? 151 LEU D CB  1 
ATOM   10558 C CG  . LEU D 1 151 ? 21.691  43.021  -0.915  1.00 34.60  ? 151 LEU D CG  1 
ATOM   10559 C CD1 . LEU D 1 151 ? 22.379  41.953  -0.066  1.00 28.11  ? 151 LEU D CD1 1 
ATOM   10560 C CD2 . LEU D 1 151 ? 21.732  44.369  -0.211  1.00 36.05  ? 151 LEU D CD2 1 
ATOM   10561 N N   . ALA D 1 152 ? 22.740  43.326  -5.366  1.00 27.93  ? 152 ALA D N   1 
ATOM   10562 C CA  . ALA D 1 152 ? 23.684  43.337  -6.475  1.00 25.02  ? 152 ALA D CA  1 
ATOM   10563 C C   . ALA D 1 152 ? 23.487  44.571  -7.329  1.00 26.19  ? 152 ALA D C   1 
ATOM   10564 O O   . ALA D 1 152 ? 24.460  45.182  -7.795  1.00 26.14  ? 152 ALA D O   1 
ATOM   10565 C CB  . ALA D 1 152 ? 23.521  42.074  -7.316  1.00 28.54  ? 152 ALA D CB  1 
ATOM   10566 N N   . ALA D 1 153 ? 22.231  44.970  -7.527  1.00 27.53  ? 153 ALA D N   1 
ATOM   10567 C CA  . ALA D 1 153 ? 21.971  46.094  -8.416  1.00 26.00  ? 153 ALA D CA  1 
ATOM   10568 C C   . ALA D 1 153 ? 22.362  47.407  -7.759  1.00 25.26  ? 153 ALA D C   1 
ATOM   10569 O O   . ALA D 1 153 ? 22.923  48.293  -8.408  1.00 25.89  ? 153 ALA D O   1 
ATOM   10570 C CB  . ALA D 1 153 ? 20.502  46.098  -8.818  1.00 24.88  ? 153 ALA D CB  1 
ATOM   10571 N N   . GLY D 1 154 ? 22.078  47.557  -6.471  1.00 25.99  ? 154 GLY D N   1 
ATOM   10572 C CA  . GLY D 1 154 ? 22.473  48.778  -5.798  1.00 29.38  ? 154 GLY D CA  1 
ATOM   10573 C C   . GLY D 1 154 ? 23.973  48.895  -5.692  1.00 28.53  ? 154 GLY D C   1 
ATOM   10574 O O   . GLY D 1 154 ? 24.521  50.001  -5.707  1.00 33.03  ? 154 GLY D O   1 
ATOM   10575 N N   . LEU D 1 155 ? 24.659  47.765  -5.632  1.00 27.03  ? 155 LEU D N   1 
ATOM   10576 C CA  . LEU D 1 155 ? 26.101  47.765  -5.472  1.00 24.80  ? 155 LEU D CA  1 
ATOM   10577 C C   . LEU D 1 155 ? 26.841  47.919  -6.788  1.00 30.59  ? 155 LEU D C   1 
ATOM   10578 O O   . LEU D 1 155 ? 27.996  48.361  -6.786  1.00 28.97  ? 155 LEU D O   1 
ATOM   10579 C CB  . LEU D 1 155 ? 26.524  46.468  -4.778  1.00 32.36  ? 155 LEU D CB  1 
ATOM   10580 C CG  . LEU D 1 155 ? 27.943  46.327  -4.246  1.00 32.50  ? 155 LEU D CG  1 
ATOM   10581 C CD1 . LEU D 1 155 ? 28.230  47.422  -3.226  1.00 30.82  ? 155 LEU D CD1 1 
ATOM   10582 C CD2 . LEU D 1 155 ? 28.089  44.935  -3.620  1.00 30.08  ? 155 LEU D CD2 1 
ATOM   10583 N N   . GLY D 1 156 ? 26.208  47.596  -7.911  1.00 29.31  ? 156 GLY D N   1 
ATOM   10584 C CA  . GLY D 1 156 ? 26.920  47.573  -9.171  1.00 28.64  ? 156 GLY D CA  1 
ATOM   10585 C C   . GLY D 1 156 ? 27.551  46.237  -9.501  1.00 30.94  ? 156 GLY D C   1 
ATOM   10586 O O   . GLY D 1 156 ? 28.352  46.163  -10.434 1.00 27.59  ? 156 GLY D O   1 
ATOM   10587 N N   . THR D 1 157 ? 27.224  45.191  -8.752  1.00 27.51  ? 157 THR D N   1 
ATOM   10588 C CA  . THR D 1 157 ? 27.705  43.853  -9.046  1.00 26.76  ? 157 THR D CA  1 
ATOM   10589 C C   . THR D 1 157 ? 27.129  43.338  -10.368 1.00 30.18  ? 157 THR D C   1 
ATOM   10590 O O   . THR D 1 157 ? 25.950  43.560  -10.666 1.00 28.10  ? 157 THR D O   1 
ATOM   10591 C CB  . THR D 1 157 ? 27.299  42.944  -7.896  1.00 27.19  ? 157 THR D CB  1 
ATOM   10592 O OG1 . THR D 1 157 ? 27.616  43.608  -6.662  1.00 32.35  ? 157 THR D OG1 1 
ATOM   10593 C CG2 . THR D 1 157 ? 27.990  41.597  -7.974  1.00 24.72  ? 157 THR D CG2 1 
ATOM   10594 N N   . PRO D 1 158 ? 27.919  42.640  -11.182 1.00 25.31  ? 158 PRO D N   1 
ATOM   10595 C CA  . PRO D 1 158 ? 27.409  42.193  -12.490 1.00 27.90  ? 158 PRO D CA  1 
ATOM   10596 C C   . PRO D 1 158 ? 26.344  41.120  -12.333 1.00 29.24  ? 158 PRO D C   1 
ATOM   10597 O O   . PRO D 1 158 ? 26.590  40.060  -11.757 1.00 32.38  ? 158 PRO D O   1 
ATOM   10598 C CB  . PRO D 1 158 ? 28.655  41.660  -13.213 1.00 32.69  ? 158 PRO D CB  1 
ATOM   10599 C CG  . PRO D 1 158 ? 29.812  41.807  -12.277 1.00 30.12  ? 158 PRO D CG  1 
ATOM   10600 C CD  . PRO D 1 158 ? 29.379  42.511  -11.042 1.00 28.64  ? 158 PRO D CD  1 
ATOM   10601 N N   . LEU D 1 159 ? 25.154  41.401  -12.859 1.00 29.63  ? 159 LEU D N   1 
ATOM   10602 C CA  . LEU D 1 159 ? 24.028  40.481  -12.798 1.00 34.00  ? 159 LEU D CA  1 
ATOM   10603 C C   . LEU D 1 159 ? 23.238  40.572  -14.099 1.00 32.34  ? 159 LEU D C   1 
ATOM   10604 O O   . LEU D 1 159 ? 23.200  41.624  -14.746 1.00 32.80  ? 159 LEU D O   1 
ATOM   10605 C CB  . LEU D 1 159 ? 23.117  40.779  -11.591 1.00 28.18  ? 159 LEU D CB  1 
ATOM   10606 C CG  . LEU D 1 159 ? 22.144  41.943  -11.756 1.00 33.04  ? 159 LEU D CG  1 
ATOM   10607 C CD1 . LEU D 1 159 ? 21.055  41.922  -10.693 1.00 29.37  ? 159 LEU D CD1 1 
ATOM   10608 C CD2 . LEU D 1 159 ? 22.894  43.238  -11.725 1.00 34.32  ? 159 LEU D CD2 1 
ATOM   10609 N N   . THR D 1 160 ? 22.625  39.452  -14.491 1.00 29.47  ? 160 THR D N   1 
ATOM   10610 C CA  . THR D 1 160 ? 21.849  39.430  -15.727 1.00 33.92  ? 160 THR D CA  1 
ATOM   10611 C C   . THR D 1 160 ? 20.625  40.328  -15.601 1.00 29.36  ? 160 THR D C   1 
ATOM   10612 O O   . THR D 1 160 ? 20.102  40.565  -14.507 1.00 31.14  ? 160 THR D O   1 
ATOM   10613 C CB  . THR D 1 160 ? 21.390  38.006  -16.074 1.00 32.36  ? 160 THR D CB  1 
ATOM   10614 O OG1 . THR D 1 160 ? 20.394  37.574  -15.125 1.00 35.01  ? 160 THR D OG1 1 
ATOM   10615 C CG2 . THR D 1 160 ? 22.552  37.052  -16.047 1.00 36.43  ? 160 THR D CG2 1 
ATOM   10616 N N   . ASP D 1 161 ? 20.157  40.822  -16.742 1.00 31.92  ? 161 ASP D N   1 
ATOM   10617 C CA  . ASP D 1 161 ? 18.887  41.540  -16.756 1.00 32.89  ? 161 ASP D CA  1 
ATOM   10618 C C   . ASP D 1 161 ? 17.790  40.639  -16.202 1.00 27.40  ? 161 ASP D C   1 
ATOM   10619 O O   . ASP D 1 161 ? 17.728  39.450  -16.518 1.00 31.98  ? 161 ASP D O   1 
ATOM   10620 C CB  . ASP D 1 161 ? 18.533  41.982  -18.179 1.00 33.88  ? 161 ASP D CB  1 
ATOM   10621 C CG  . ASP D 1 161 ? 19.395  43.128  -18.674 1.00 43.75  ? 161 ASP D CG  1 
ATOM   10622 O OD1 . ASP D 1 161 ? 20.429  43.437  -18.037 1.00 44.11  ? 161 ASP D OD1 1 
ATOM   10623 O OD2 . ASP D 1 161 ? 19.035  43.722  -19.716 1.00 55.43  ? 161 ASP D OD2 1 
ATOM   10624 N N   . GLY D 1 162 ? 16.936  41.194  -15.357 1.00 27.97  ? 162 GLY D N   1 
ATOM   10625 C CA  . GLY D 1 162 ? 15.895  40.384  -14.748 1.00 25.89  ? 162 GLY D CA  1 
ATOM   10626 C C   . GLY D 1 162 ? 14.943  41.249  -13.958 1.00 24.67  ? 162 GLY D C   1 
ATOM   10627 O O   . GLY D 1 162 ? 15.187  42.435  -13.742 1.00 25.38  ? 162 GLY D O   1 
ATOM   10628 N N   . VAL D 1 163 ? 13.846  40.637  -13.522 1.00 25.29  ? 163 VAL D N   1 
ATOM   10629 C CA  . VAL D 1 163 ? 12.863  41.330  -12.709 1.00 27.34  ? 163 VAL D CA  1 
ATOM   10630 C C   . VAL D 1 163 ? 12.483  40.478  -11.507 1.00 28.68  ? 163 VAL D C   1 
ATOM   10631 O O   . VAL D 1 163 ? 12.472  39.243  -11.565 1.00 26.65  ? 163 VAL D O   1 
ATOM   10632 C CB  . VAL D 1 163 ? 11.588  41.700  -13.508 1.00 28.91  ? 163 VAL D CB  1 
ATOM   10633 C CG1 . VAL D 1 163 ? 11.940  42.299  -14.864 1.00 27.42  ? 163 VAL D CG1 1 
ATOM   10634 C CG2 . VAL D 1 163 ? 10.714  40.498  -13.662 1.00 30.82  ? 163 VAL D CG2 1 
ATOM   10635 N N   . VAL D 1 164 ? 12.156  41.163  -10.410 1.00 29.04  ? 164 VAL D N   1 
ATOM   10636 C CA  . VAL D 1 164 ? 11.472  40.559  -9.271  1.00 23.96  ? 164 VAL D CA  1 
ATOM   10637 C C   . VAL D 1 164 ? 9.977   40.742  -9.532  1.00 28.54  ? 164 VAL D C   1 
ATOM   10638 O O   . VAL D 1 164 ? 9.375   41.784  -9.213  1.00 25.54  ? 164 VAL D O   1 
ATOM   10639 C CB  . VAL D 1 164 ? 11.916  41.183  -7.950  1.00 29.42  ? 164 VAL D CB  1 
ATOM   10640 C CG1 . VAL D 1 164 ? 11.274  40.480  -6.786  1.00 26.19  ? 164 VAL D CG1 1 
ATOM   10641 C CG2 . VAL D 1 164 ? 13.432  41.162  -7.828  1.00 27.58  ? 164 VAL D CG2 1 
ATOM   10642 N N   . ALA D 1 165 ? 9.367   39.717  -10.127 1.00 30.74  ? 165 ALA D N   1 
ATOM   10643 C CA  . ALA D 1 165 ? 7.960   39.757  -10.517 1.00 31.95  ? 165 ALA D CA  1 
ATOM   10644 C C   . ALA D 1 165 ? 7.055   39.509  -9.315  1.00 32.06  ? 165 ALA D C   1 
ATOM   10645 O O   . ALA D 1 165 ? 7.314   38.627  -8.493  1.00 26.20  ? 165 ALA D O   1 
ATOM   10646 C CB  . ALA D 1 165 ? 7.670   38.714  -11.601 1.00 27.72  ? 165 ALA D CB  1 
ATOM   10647 N N   . ARG D 1 166 ? 5.975   40.289  -9.243  1.00 32.35  ? 166 ARG D N   1 
ATOM   10648 C CA  . ARG D 1 166 ? 5.059   40.317  -8.113  1.00 39.54  ? 166 ARG D CA  1 
ATOM   10649 C C   . ARG D 1 166 ? 3.706   39.677  -8.412  1.00 35.38  ? 166 ARG D C   1 
ATOM   10650 O O   . ARG D 1 166 ? 2.908   39.483  -7.486  1.00 39.01  ? 166 ARG D O   1 
ATOM   10651 C CB  . ARG D 1 166 ? 4.868   41.778  -7.651  1.00 36.08  ? 166 ARG D CB  1 
ATOM   10652 C CG  . ARG D 1 166 ? 6.167   42.412  -7.082  1.00 39.74  ? 166 ARG D CG  1 
ATOM   10653 C CD  . ARG D 1 166 ? 6.151   43.948  -7.065  1.00 35.70  ? 166 ARG D CD  1 
ATOM   10654 N NE  . ARG D 1 166 ? 6.318   44.528  -8.390  1.00 32.74  ? 166 ARG D NE  1 
ATOM   10655 C CZ  . ARG D 1 166 ? 6.286   45.828  -8.647  1.00 37.23  ? 166 ARG D CZ  1 
ATOM   10656 N NH1 . ARG D 1 166 ? 6.158   46.721  -7.680  1.00 35.27  ? 166 ARG D NH1 1 
ATOM   10657 N NH2 . ARG D 1 166 ? 6.369   46.243  -9.908  1.00 36.57  ? 166 ARG D NH2 1 
ATOM   10658 N N   . GLY D 1 167 ? 3.438   39.330  -9.665  1.00 34.77  ? 167 GLY D N   1 
ATOM   10659 C CA  . GLY D 1 167 ? 2.228   38.636  -10.046 1.00 35.63  ? 167 GLY D CA  1 
ATOM   10660 C C   . GLY D 1 167 ? 2.392   37.990  -11.408 1.00 33.01  ? 167 GLY D C   1 
ATOM   10661 O O   . GLY D 1 167 ? 3.415   38.158  -12.069 1.00 30.39  ? 167 GLY D O   1 
ATOM   10662 N N   . PRO D 1 168 ? 1.398   37.227  -11.856 1.00 36.05  ? 168 PRO D N   1 
ATOM   10663 C CA  . PRO D 1 168 ? 1.525   36.601  -13.183 1.00 34.79  ? 168 PRO D CA  1 
ATOM   10664 C C   . PRO D 1 168 ? 1.634   37.604  -14.318 1.00 34.93  ? 168 PRO D C   1 
ATOM   10665 O O   . PRO D 1 168 ? 2.394   37.367  -15.270 1.00 37.16  ? 168 PRO D O   1 
ATOM   10666 C CB  . PRO D 1 168 ? 0.261   35.737  -13.300 1.00 38.12  ? 168 PRO D CB  1 
ATOM   10667 C CG  . PRO D 1 168 ? -0.658  36.194  -12.227 1.00 35.12  ? 168 PRO D CG  1 
ATOM   10668 C CD  . PRO D 1 168 ? 0.165   36.839  -11.152 1.00 37.60  ? 168 PRO D CD  1 
ATOM   10669 N N   . ALA D 1 169 ? 0.926   38.730  -14.240 1.00 33.30  ? 169 ALA D N   1 
ATOM   10670 C CA  . ALA D 1 169 ? 1.012   39.722  -15.309 1.00 34.59  ? 169 ALA D CA  1 
ATOM   10671 C C   . ALA D 1 169 ? 2.436   40.240  -15.476 1.00 35.57  ? 169 ALA D C   1 
ATOM   10672 O O   . ALA D 1 169 ? 2.911   40.415  -16.606 1.00 42.25  ? 169 ALA D O   1 
ATOM   10673 C CB  . ALA D 1 169 ? 0.052   40.881  -15.040 1.00 30.73  ? 169 ALA D CB  1 
ATOM   10674 N N   . GLU D 1 170 ? 3.136   40.488  -14.366 1.00 31.94  ? 170 GLU D N   1 
ATOM   10675 C CA  . GLU D 1 170 ? 4.522   40.923  -14.451 1.00 31.16  ? 170 GLU D CA  1 
ATOM   10676 C C   . GLU D 1 170 ? 5.477   39.784  -14.819 1.00 33.62  ? 170 GLU D C   1 
ATOM   10677 O O   . GLU D 1 170 ? 6.560   40.046  -15.344 1.00 32.99  ? 170 GLU D O   1 
ATOM   10678 C CB  . GLU D 1 170 ? 4.951   41.587  -13.134 1.00 32.34  ? 170 GLU D CB  1 
ATOM   10679 C CG  . GLU D 1 170 ? 6.245   42.377  -13.242 1.00 31.75  ? 170 GLU D CG  1 
ATOM   10680 C CD  . GLU D 1 170 ? 6.515   43.273  -12.033 1.00 33.50  ? 170 GLU D CD  1 
ATOM   10681 O OE1 . GLU D 1 170 ? 6.184   42.868  -10.899 1.00 35.79  ? 170 GLU D OE1 1 
ATOM   10682 O OE2 . GLU D 1 170 ? 7.068   44.382  -12.220 1.00 31.15  ? 170 GLU D OE2 1 
ATOM   10683 N N   . VAL D 1 171 ? 5.110   38.524  -14.596 1.00 30.25  ? 171 VAL D N   1 
ATOM   10684 C CA  . VAL D 1 171 ? 5.894   37.457  -15.211 1.00 28.82  ? 171 VAL D CA  1 
ATOM   10685 C C   . VAL D 1 171 ? 5.748   37.493  -16.731 1.00 30.77  ? 171 VAL D C   1 
ATOM   10686 O O   . VAL D 1 171 ? 6.724   37.298  -17.461 1.00 29.87  ? 171 VAL D O   1 
ATOM   10687 C CB  . VAL D 1 171 ? 5.498   36.083  -14.645 1.00 30.27  ? 171 VAL D CB  1 
ATOM   10688 C CG1 . VAL D 1 171 ? 6.281   34.971  -15.355 1.00 22.28  ? 171 VAL D CG1 1 
ATOM   10689 C CG2 . VAL D 1 171 ? 5.738   36.035  -13.138 1.00 27.24  ? 171 VAL D CG2 1 
ATOM   10690 N N   . ARG D 1 172 ? 4.534   37.753  -17.233 1.00 30.07  ? 172 ARG D N   1 
ATOM   10691 C CA  . ARG D 1 172 ? 4.300   37.759  -18.676 1.00 29.99  ? 172 ARG D CA  1 
ATOM   10692 C C   . ARG D 1 172 ? 5.173   38.797  -19.366 1.00 34.75  ? 172 ARG D C   1 
ATOM   10693 O O   . ARG D 1 172 ? 5.933   38.473  -20.289 1.00 31.23  ? 172 ARG D O   1 
ATOM   10694 C CB  . ARG D 1 172 ? 2.815   38.020  -18.972 1.00 38.47  ? 172 ARG D CB  1 
ATOM   10695 C CG  . ARG D 1 172 ? 2.332   37.558  -20.358 1.00 38.76  ? 172 ARG D CG  1 
ATOM   10696 C CD  . ARG D 1 172 ? 1.030   38.259  -20.792 1.00 38.34  ? 172 ARG D CD  1 
ATOM   10697 N NE  . ARG D 1 172 ? 0.592   37.877  -22.135 1.00 41.05  ? 172 ARG D NE  1 
ATOM   10698 C CZ  . ARG D 1 172 ? 0.947   38.502  -23.256 1.00 43.13  ? 172 ARG D CZ  1 
ATOM   10699 N NH1 . ARG D 1 172 ? 1.771   39.540  -23.241 1.00 32.64  ? 172 ARG D NH1 1 
ATOM   10700 N NH2 . ARG D 1 172 ? 0.481   38.061  -24.424 1.00 41.74  ? 172 ARG D NH2 1 
ATOM   10701 N N   . SER D 1 173 ? 5.093   40.056  -18.915 1.00 33.50  ? 173 SER D N   1 
ATOM   10702 C CA  . SER D 1 173 ? 5.959   41.093  -19.472 1.00 32.28  ? 173 SER D CA  1 
ATOM   10703 C C   . SER D 1 173 ? 7.433   40.748  -19.283 1.00 33.53  ? 173 SER D C   1 
ATOM   10704 O O   . SER D 1 173 ? 8.260   41.021  -20.167 1.00 35.17  ? 173 SER D O   1 
ATOM   10705 C CB  . SER D 1 173 ? 5.630   42.443  -18.835 1.00 32.68  ? 173 SER D CB  1 
ATOM   10706 O OG  . SER D 1 173 ? 5.299   42.286  -17.465 1.00 38.88  ? 173 SER D OG  1 
ATOM   10707 N N   . ALA D 1 174 ? 7.774   40.122  -18.155 1.00 33.10  ? 174 ALA D N   1 
ATOM   10708 C CA  . ALA D 1 174 ? 9.160   39.735  -17.897 1.00 30.62  ? 174 ALA D CA  1 
ATOM   10709 C C   . ALA D 1 174 ? 9.690   38.807  -18.980 1.00 32.60  ? 174 ALA D C   1 
ATOM   10710 O O   . ALA D 1 174 ? 10.754  39.053  -19.562 1.00 31.23  ? 174 ALA D O   1 
ATOM   10711 C CB  . ALA D 1 174 ? 9.269   39.053  -16.536 1.00 31.41  ? 174 ALA D CB  1 
ATOM   10712 N N   . ILE D 1 175 ? 8.977   37.710  -19.235 1.00 29.90  ? 175 ILE D N   1 
ATOM   10713 C CA  . ILE D 1 175 ? 9.408   36.784  -20.272 1.00 30.26  ? 175 ILE D CA  1 
ATOM   10714 C C   . ILE D 1 175 ? 9.533   37.505  -21.606 1.00 35.65  ? 175 ILE D C   1 
ATOM   10715 O O   . ILE D 1 175 ? 10.530  37.359  -22.322 1.00 35.57  ? 175 ILE D O   1 
ATOM   10716 C CB  . ILE D 1 175 ? 8.439   35.601  -20.370 1.00 25.65  ? 175 ILE D CB  1 
ATOM   10717 C CG1 . ILE D 1 175 ? 8.209   34.984  -18.993 1.00 32.45  ? 175 ILE D CG1 1 
ATOM   10718 C CG2 . ILE D 1 175 ? 9.010   34.581  -21.317 1.00 29.54  ? 175 ILE D CG2 1 
ATOM   10719 C CD1 . ILE D 1 175 ? 7.034   34.021  -18.923 1.00 29.64  ? 175 ILE D CD1 1 
ATOM   10720 N N   . GLN D 1 176 ? 8.519   38.303  -21.952 1.00 36.43  ? 176 GLN D N   1 
ATOM   10721 C CA  . GLN D 1 176 ? 8.482   38.924  -23.271 1.00 38.60  ? 176 GLN D CA  1 
ATOM   10722 C C   . GLN D 1 176 ? 9.711   39.789  -23.509 1.00 42.41  ? 176 GLN D C   1 
ATOM   10723 O O   . GLN D 1 176 ? 10.316  39.741  -24.587 1.00 43.89  ? 176 GLN D O   1 
ATOM   10724 C CB  . GLN D 1 176 ? 7.207   39.754  -23.425 1.00 37.47  ? 176 GLN D CB  1 
ATOM   10725 C CG  . GLN D 1 176 ? 7.176   40.557  -24.716 1.00 47.29  ? 176 GLN D CG  1 
ATOM   10726 C CD  . GLN D 1 176 ? 5.944   40.278  -25.553 1.00 47.25  ? 176 GLN D CD  1 
ATOM   10727 O OE1 . GLN D 1 176 ? 4.821   40.273  -25.042 1.00 52.59  ? 176 GLN D OE1 1 
ATOM   10728 N NE2 . GLN D 1 176 ? 6.149   40.022  -26.848 1.00 43.92  ? 176 GLN D NE2 1 
ATOM   10729 N N   . GLU D 1 177 ? 10.114  40.569  -22.507 1.00 36.13  ? 177 GLU D N   1 
ATOM   10730 C CA  . GLU D 1 177 ? 11.246  41.456  -22.711 1.00 36.57  ? 177 GLU D CA  1 
ATOM   10731 C C   . GLU D 1 177 ? 12.587  40.740  -22.543 1.00 37.62  ? 177 GLU D C   1 
ATOM   10732 O O   . GLU D 1 177 ? 13.548  41.060  -23.254 1.00 36.99  ? 177 GLU D O   1 
ATOM   10733 C CB  . GLU D 1 177 ? 11.124  42.644  -21.761 1.00 39.69  ? 177 GLU D CB  1 
ATOM   10734 C CG  . GLU D 1 177 ? 12.387  43.469  -21.589 1.00 44.70  ? 177 GLU D CG  1 
ATOM   10735 C CD  . GLU D 1 177 ? 12.588  43.863  -20.145 1.00 56.84  ? 177 GLU D CD  1 
ATOM   10736 O OE1 . GLU D 1 177 ? 11.578  43.843  -19.397 1.00 52.39  ? 177 GLU D OE1 1 
ATOM   10737 O OE2 . GLU D 1 177 ? 13.733  44.216  -19.764 1.00 53.20  ? 177 GLU D OE2 1 
ATOM   10738 N N   . LEU D 1 178 ? 12.675  39.759  -21.646 1.00 28.97  ? 178 LEU D N   1 
ATOM   10739 C CA  . LEU D 1 178 ? 13.957  39.125  -21.352 1.00 33.78  ? 178 LEU D CA  1 
ATOM   10740 C C   . LEU D 1 178 ? 14.311  37.969  -22.294 1.00 35.39  ? 178 LEU D C   1 
ATOM   10741 O O   . LEU D 1 178 ? 15.467  37.530  -22.287 1.00 33.74  ? 178 LEU D O   1 
ATOM   10742 C CB  . LEU D 1 178 ? 13.970  38.637  -19.901 1.00 29.89  ? 178 LEU D CB  1 
ATOM   10743 C CG  . LEU D 1 178 ? 13.811  39.768  -18.877 1.00 35.18  ? 178 LEU D CG  1 
ATOM   10744 C CD1 . LEU D 1 178 ? 13.317  39.243  -17.524 1.00 29.39  ? 178 LEU D CD1 1 
ATOM   10745 C CD2 . LEU D 1 178 ? 15.119  40.571  -18.715 1.00 32.10  ? 178 LEU D CD2 1 
ATOM   10746 N N   . ILE D 1 179 ? 13.367  37.482  -23.111 1.00 31.21  ? 179 ILE D N   1 
ATOM   10747 C CA  . ILE D 1 179 ? 13.644  36.392  -24.052 1.00 30.43  ? 179 ILE D CA  1 
ATOM   10748 C C   . ILE D 1 179 ? 14.440  36.862  -25.272 1.00 35.37  ? 179 ILE D C   1 
ATOM   10749 O O   . ILE D 1 179 ? 15.064  36.041  -25.960 1.00 31.13  ? 179 ILE D O   1 
ATOM   10750 C CB  . ILE D 1 179 ? 12.320  35.717  -24.494 1.00 35.55  ? 179 ILE D CB  1 
ATOM   10751 C CG1 . ILE D 1 179 ? 12.563  34.322  -25.089 1.00 32.20  ? 179 ILE D CG1 1 
ATOM   10752 C CG2 . ILE D 1 179 ? 11.549  36.603  -25.477 1.00 33.80  ? 179 ILE D CG2 1 
ATOM   10753 C CD1 . ILE D 1 179 ? 12.764  33.224  -24.063 1.00 24.90  ? 179 ILE D CD1 1 
ATOM   10754 N N   . ALA D 1 180 ? 14.456  38.165  -25.550 1.00 33.44  ? 180 ALA D N   1 
ATOM   10755 C CA  . ALA D 1 180 ? 15.057  38.646  -26.791 1.00 34.73  ? 180 ALA D CA  1 
ATOM   10756 C C   . ALA D 1 180 ? 16.550  38.325  -26.864 1.00 38.19  ? 180 ALA D C   1 
ATOM   10757 O O   . ALA D 1 180 ? 17.030  37.800  -27.874 1.00 38.88  ? 180 ALA D O   1 
ATOM   10758 C CB  . ALA D 1 180 ? 14.814  40.150  -26.933 1.00 26.49  ? 180 ALA D CB  1 
ATOM   10759 N N   . GLU D 1 181 ? 17.299  38.604  -25.789 1.00 34.44  ? 181 GLU D N   1 
ATOM   10760 C CA  . GLU D 1 181 ? 18.761  38.647  -25.891 1.00 37.72  ? 181 GLU D CA  1 
ATOM   10761 C C   . GLU D 1 181 ? 19.362  37.301  -26.293 1.00 36.74  ? 181 GLU D C   1 
ATOM   10762 O O   . GLU D 1 181 ? 20.290  37.250  -27.107 1.00 37.34  ? 181 GLU D O   1 
ATOM   10763 C CB  . GLU D 1 181 ? 19.373  39.121  -24.566 1.00 33.12  ? 181 GLU D CB  1 
ATOM   10764 C CG  . GLU D 1 181 ? 20.873  39.477  -24.657 1.00 40.60  ? 181 GLU D CG  1 
ATOM   10765 C CD  . GLU D 1 181 ? 21.451  40.010  -23.338 1.00 48.19  ? 181 GLU D CD  1 
ATOM   10766 O OE1 . GLU D 1 181 ? 20.701  40.077  -22.324 1.00 41.79  ? 181 GLU D OE1 1 
ATOM   10767 O OE2 . GLU D 1 181 ? 22.654  40.375  -23.324 1.00 45.69  ? 181 GLU D OE2 1 
ATOM   10768 N N   . THR D 1 182 ? 18.886  36.206  -25.700 1.00 34.86  ? 182 THR D N   1 
ATOM   10769 C CA  . THR D 1 182 ? 19.467  34.891  -25.931 1.00 35.30  ? 182 THR D CA  1 
ATOM   10770 C C   . THR D 1 182 ? 18.455  33.834  -26.326 1.00 34.14  ? 182 THR D C   1 
ATOM   10771 O O   . THR D 1 182 ? 18.867  32.739  -26.713 1.00 34.42  ? 182 THR D O   1 
ATOM   10772 C CB  . THR D 1 182 ? 20.197  34.378  -24.678 1.00 30.79  ? 182 THR D CB  1 
ATOM   10773 O OG1 . THR D 1 182 ? 19.226  34.062  -23.669 1.00 33.53  ? 182 THR D OG1 1 
ATOM   10774 C CG2 . THR D 1 182 ? 21.157  35.417  -24.139 1.00 36.29  ? 182 THR D CG2 1 
ATOM   10775 N N   . GLY D 1 183 ? 17.160  34.104  -26.221 1.00 36.47  ? 183 GLY D N   1 
ATOM   10776 C CA  . GLY D 1 183 ? 16.174  33.061  -26.416 1.00 32.31  ? 183 GLY D CA  1 
ATOM   10777 C C   . GLY D 1 183 ? 15.972  32.151  -25.224 1.00 34.79  ? 183 GLY D C   1 
ATOM   10778 O O   . GLY D 1 183 ? 15.256  31.154  -25.343 1.00 32.21  ? 183 GLY D O   1 
ATOM   10779 N N   . MET D 1 184 ? 16.584  32.448  -24.078 1.00 32.32  ? 184 MET D N   1 
ATOM   10780 C CA  . MET D 1 184 ? 16.424  31.629  -22.887 1.00 32.88  ? 184 MET D CA  1 
ATOM   10781 C C   . MET D 1 184 ? 16.188  32.529  -21.688 1.00 30.24  ? 184 MET D C   1 
ATOM   10782 O O   . MET D 1 184 ? 16.863  33.547  -21.511 1.00 28.04  ? 184 MET D O   1 
ATOM   10783 C CB  . MET D 1 184 ? 17.642  30.745  -22.621 1.00 29.16  ? 184 MET D CB  1 
ATOM   10784 C CG  . MET D 1 184 ? 18.257  30.166  -23.881 1.00 36.52  ? 184 MET D CG  1 
ATOM   10785 S SD  . MET D 1 184 ? 19.659  29.046  -23.645 1.00 41.81  ? 184 MET D SD  1 
ATOM   10786 C CE  . MET D 1 184 ? 18.974  27.655  -22.745 1.00 35.84  ? 184 MET D CE  1 
ATOM   10787 N N   . VAL D 1 185 ? 15.238  32.124  -20.863 1.00 27.44  ? 185 VAL D N   1 
ATOM   10788 C CA  . VAL D 1 185 ? 14.827  32.851  -19.674 1.00 29.32  ? 185 VAL D CA  1 
ATOM   10789 C C   . VAL D 1 185 ? 14.635  31.810  -18.588 1.00 33.46  ? 185 VAL D C   1 
ATOM   10790 O O   . VAL D 1 185 ? 14.112  30.719  -18.852 1.00 27.34  ? 185 VAL D O   1 
ATOM   10791 C CB  . VAL D 1 185 ? 13.534  33.656  -19.927 1.00 29.22  ? 185 VAL D CB  1 
ATOM   10792 C CG1 . VAL D 1 185 ? 12.787  33.907  -18.649 1.00 28.99  ? 185 VAL D CG1 1 
ATOM   10793 C CG2 . VAL D 1 185 ? 13.859  34.959  -20.620 1.00 30.77  ? 185 VAL D CG2 1 
ATOM   10794 N N   . ILE D 1 186 ? 15.107  32.117  -17.383 1.00 27.61  ? 186 ILE D N   1 
ATOM   10795 C CA  . ILE D 1 186 ? 14.999  31.205  -16.257 1.00 28.98  ? 186 ILE D CA  1 
ATOM   10796 C C   . ILE D 1 186 ? 14.170  31.893  -15.186 1.00 25.29  ? 186 ILE D C   1 
ATOM   10797 O O   . ILE D 1 186 ? 14.363  33.083  -14.910 1.00 27.43  ? 186 ILE D O   1 
ATOM   10798 C CB  . ILE D 1 186 ? 16.384  30.778  -15.724 1.00 29.00  ? 186 ILE D CB  1 
ATOM   10799 C CG1 . ILE D 1 186 ? 16.219  29.820  -14.531 1.00 28.10  ? 186 ILE D CG1 1 
ATOM   10800 C CG2 . ILE D 1 186 ? 17.236  32.004  -15.363 1.00 27.45  ? 186 ILE D CG2 1 
ATOM   10801 C CD1 . ILE D 1 186 ? 17.397  28.909  -14.287 1.00 28.66  ? 186 ILE D CD1 1 
ATOM   10802 N N   . ALA D 1 187 ? 13.221  31.156  -14.618 1.00 27.72  ? 187 ALA D N   1 
ATOM   10803 C CA  . ALA D 1 187 ? 12.337  31.665  -13.581 1.00 31.66  ? 187 ALA D CA  1 
ATOM   10804 C C   . ALA D 1 187 ? 12.614  30.919  -12.284 1.00 30.67  ? 187 ALA D C   1 
ATOM   10805 O O   . ALA D 1 187 ? 12.718  29.686  -12.284 1.00 30.78  ? 187 ALA D O   1 
ATOM   10806 C CB  . ALA D 1 187 ? 10.874  31.521  -13.977 1.00 33.03  ? 187 ALA D CB  1 
ATOM   10807 N N   . LYS D 1 188 ? 12.752  31.663  -11.186 1.00 34.31  ? 188 LYS D N   1 
ATOM   10808 C CA  . LYS D 1 188 ? 13.238  31.079  -9.947  1.00 34.14  ? 188 LYS D CA  1 
ATOM   10809 C C   . LYS D 1 188 ? 12.263  31.301  -8.799  1.00 33.65  ? 188 LYS D C   1 
ATOM   10810 O O   . LYS D 1 188 ? 11.780  32.419  -8.586  1.00 33.13  ? 188 LYS D O   1 
ATOM   10811 C CB  . LYS D 1 188 ? 14.634  31.596  -9.581  1.00 35.97  ? 188 LYS D CB  1 
ATOM   10812 C CG  . LYS D 1 188 ? 15.708  31.099  -10.556 1.00 35.66  ? 188 LYS D CG  1 
ATOM   10813 C CD  . LYS D 1 188 ? 16.990  31.955  -10.544 1.00 34.62  ? 188 LYS D CD  1 
ATOM   10814 C CE  . LYS D 1 188 ? 18.231  31.086  -10.753 1.00 33.64  ? 188 LYS D CE  1 
ATOM   10815 N NZ  . LYS D 1 188 ? 19.468  31.921  -10.681 1.00 46.63  ? 188 LYS D NZ  1 
ATOM   10816 N N   . GLN D 1 189 ? 11.955  30.217  -8.091  1.00 34.14  ? 189 GLN D N   1 
ATOM   10817 C CA  . GLN D 1 189 ? 11.351  30.319  -6.774  1.00 36.54  ? 189 GLN D CA  1 
ATOM   10818 C C   . GLN D 1 189 ? 12.248  31.166  -5.887  1.00 34.54  ? 189 GLN D C   1 
ATOM   10819 O O   . GLN D 1 189 ? 13.459  30.951  -5.821  1.00 33.94  ? 189 GLN D O   1 
ATOM   10820 C CB  . GLN D 1 189 ? 11.159  28.934  -6.168  1.00 37.64  ? 189 GLN D CB  1 
ATOM   10821 C CG  . GLN D 1 189 ? 10.303  28.908  -4.935  1.00 44.78  ? 189 GLN D CG  1 
ATOM   10822 C CD  . GLN D 1 189 ? 9.717   27.541  -4.701  1.00 54.78  ? 189 GLN D CD  1 
ATOM   10823 O OE1 . GLN D 1 189 ? 10.364  26.524  -4.996  1.00 58.24  ? 189 GLN D OE1 1 
ATOM   10824 N NE2 . GLN D 1 189 ? 8.486   27.495  -4.178  1.00 50.71  ? 189 GLN D NE2 1 
ATOM   10825 N N   . ASP D 1 190 ? 11.655  32.149  -5.227  1.00 34.22  ? 190 ASP D N   1 
ATOM   10826 C CA  . ASP D 1 190 ? 12.462  33.130  -4.517  1.00 37.82  ? 190 ASP D CA  1 
ATOM   10827 C C   . ASP D 1 190 ? 13.345  32.518  -3.435  1.00 40.76  ? 190 ASP D C   1 
ATOM   10828 O O   . ASP D 1 190 ? 14.365  33.125  -3.083  1.00 37.19  ? 190 ASP D O   1 
ATOM   10829 C CB  . ASP D 1 190 ? 11.567  34.199  -3.910  1.00 29.48  ? 190 ASP D CB  1 
ATOM   10830 C CG  . ASP D 1 190 ? 12.314  35.498  -3.668  1.00 32.64  ? 190 ASP D CG  1 
ATOM   10831 O OD1 . ASP D 1 190 ? 13.497  35.595  -4.071  1.00 33.77  ? 190 ASP D OD1 1 
ATOM   10832 O OD2 . ASP D 1 190 ? 11.731  36.422  -3.073  1.00 29.57  ? 190 ASP D OD2 1 
ATOM   10833 N N   . ARG D 1 191 ? 12.998  31.326  -2.917  1.00 39.61  ? 191 ARG D N   1 
ATOM   10834 C CA  . ARG D 1 191 ? 13.707  30.746  -1.778  1.00 45.76  ? 191 ARG D CA  1 
ATOM   10835 C C   . ARG D 1 191 ? 14.196  29.316  -2.017  1.00 52.30  ? 191 ARG D C   1 
ATOM   10836 O O   . ARG D 1 191 ? 14.434  28.589  -1.045  1.00 57.78  ? 191 ARG D O   1 
ATOM   10837 C CB  . ARG D 1 191 ? 12.821  30.766  -0.528  1.00 50.24  ? 191 ARG D CB  1 
ATOM   10838 C CG  . ARG D 1 191 ? 12.339  32.132  -0.085  1.00 47.93  ? 191 ARG D CG  1 
ATOM   10839 C CD  . ARG D 1 191 ? 12.760  32.407  1.357   1.00 49.67  ? 191 ARG D CD  1 
ATOM   10840 N NE  . ARG D 1 191 ? 12.017  33.519  1.940   1.00 51.25  ? 191 ARG D NE  1 
ATOM   10841 C CZ  . ARG D 1 191 ? 11.393  33.473  3.108   1.00 54.91  ? 191 ARG D CZ  1 
ATOM   10842 N NH1 . ARG D 1 191 ? 11.454  32.399  3.884   1.00 62.95  ? 191 ARG D NH1 1 
ATOM   10843 N NH2 . ARG D 1 191 ? 10.693  34.529  3.512   1.00 49.08  ? 191 ARG D NH2 1 
ATOM   10844 N N   . SER D 1 192 ? 14.369  28.885  -3.281  1.00 54.25  ? 192 SER D N   1 
ATOM   10845 C CA  . SER D 1 192 ? 14.720  27.487  -3.618  1.00 58.52  ? 192 SER D CA  1 
ATOM   10846 C C   . SER D 1 192 ? 15.951  27.456  -4.540  1.00 61.88  ? 192 SER D C   1 
ATOM   10847 O O   . SER D 1 192 ? 15.828  27.236  -5.753  1.00 53.64  ? 192 SER D O   1 
ATOM   10848 C CB  . SER D 1 192 ? 13.513  26.758  -4.271  1.00 58.68  ? 192 SER D CB  1 
ATOM   10849 O OG  . SER D 1 192 ? 12.317  26.914  -3.522  1.00 57.15  ? 192 SER D OG  1 
ATOM   10850 N N   . GLY D 1 193 ? 17.139  27.654  -3.959  1.00 58.22  ? 193 GLY D N   1 
ATOM   10851 C CA  . GLY D 1 193 ? 18.339  27.875  -4.755  1.00 62.65  ? 193 GLY D CA  1 
ATOM   10852 C C   . GLY D 1 193 ? 19.206  26.660  -5.028  1.00 70.33  ? 193 GLY D C   1 
ATOM   10853 O O   . GLY D 1 193 ? 20.350  26.592  -4.562  1.00 70.10  ? 193 GLY D O   1 
ATOM   10854 N N   . GLY D 1 194 ? 18.683  25.702  -5.797  1.00 72.11  ? 194 GLY D N   1 
ATOM   10855 C CA  . GLY D 1 194 ? 19.428  24.500  -6.121  1.00 72.63  ? 194 GLY D CA  1 
ATOM   10856 C C   . GLY D 1 194 ? 18.870  23.707  -7.287  1.00 71.25  ? 194 GLY D C   1 
ATOM   10857 O O   . GLY D 1 194 ? 19.052  22.486  -7.354  1.00 77.55  ? 194 GLY D O   1 
ATOM   10858 N N   . GLY D 1 195 ? 18.187  24.381  -8.206  1.00 60.03  ? 195 GLY D N   1 
ATOM   10859 C CA  . GLY D 1 195 ? 17.733  23.769  -9.445  1.00 60.69  ? 195 GLY D CA  1 
ATOM   10860 C C   . GLY D 1 195 ? 16.316  23.230  -9.471  1.00 62.20  ? 195 GLY D C   1 
ATOM   10861 O O   . GLY D 1 195 ? 15.603  23.428  -10.456 1.00 55.32  ? 195 GLY D O   1 
ATOM   10862 N N   . HIS D 1 196 ? 15.892  22.552  -8.398  1.00 68.31  ? 196 HIS D N   1 
ATOM   10863 C CA  . HIS D 1 196 ? 14.578  21.908  -8.380  1.00 67.24  ? 196 HIS D CA  1 
ATOM   10864 C C   . HIS D 1 196 ? 13.459  22.920  -8.557  1.00 65.14  ? 196 HIS D C   1 
ATOM   10865 O O   . HIS D 1 196 ? 12.536  22.717  -9.352  1.00 59.37  ? 196 HIS D O   1 
ATOM   10866 C CB  . HIS D 1 196 ? 14.369  21.152  -7.068  1.00 76.96  ? 196 HIS D CB  1 
ATOM   10867 C CG  . HIS D 1 196 ? 15.527  20.301  -6.667  1.00 82.32  ? 196 HIS D CG  1 
ATOM   10868 N ND1 . HIS D 1 196 ? 15.612  18.965  -6.991  1.00 89.59  ? 196 HIS D ND1 1 
ATOM   10869 C CD2 . HIS D 1 196 ? 16.643  20.591  -5.958  1.00 84.73  ? 196 HIS D CD2 1 
ATOM   10870 C CE1 . HIS D 1 196 ? 16.734  18.468  -6.503  1.00 93.77  ? 196 HIS D CE1 1 
ATOM   10871 N NE2 . HIS D 1 196 ? 17.378  19.434  -5.871  1.00 94.01  ? 196 HIS D NE2 1 
ATOM   10872 N N   . GLY D 1 197 ? 13.495  23.999  -7.793  1.00 64.99  ? 197 GLY D N   1 
ATOM   10873 C CA  . GLY D 1 197 ? 12.426  24.951  -7.930  1.00 57.05  ? 197 GLY D CA  1 
ATOM   10874 C C   . GLY D 1 197 ? 12.757  25.930  -9.028  1.00 56.79  ? 197 GLY D C   1 
ATOM   10875 O O   . GLY D 1 197 ? 12.580  27.133  -8.805  1.00 51.66  ? 197 GLY D O   1 
ATOM   10876 N N   . ASN D 1 198 ? 13.252  25.454  -10.186 1.00 44.46  ? 198 ASN D N   1 
ATOM   10877 C CA  . ASN D 1 198 ? 13.677  26.305  -11.297 1.00 39.85  ? 198 ASN D CA  1 
ATOM   10878 C C   . ASN D 1 198 ? 13.085  25.838  -12.625 1.00 39.99  ? 198 ASN D C   1 
ATOM   10879 O O   . ASN D 1 198 ? 13.199  24.664  -12.978 1.00 39.38  ? 198 ASN D O   1 
ATOM   10880 C CB  . ASN D 1 198 ? 15.204  26.371  -11.413 1.00 47.24  ? 198 ASN D CB  1 
ATOM   10881 C CG  . ASN D 1 198 ? 15.872  27.085  -10.228 1.00 48.04  ? 198 ASN D CG  1 
ATOM   10882 O OD1 . ASN D 1 198 ? 15.209  27.750  -9.429  1.00 35.90  ? 198 ASN D OD1 1 
ATOM   10883 N ND2 . ASN D 1 198 ? 17.201  27.003  -10.161 1.00 40.23  ? 198 ASN D ND2 1 
ATOM   10884 N N   . ILE D 1 199 ? 12.497  26.765  -13.382 1.00 35.46  ? 199 ILE D N   1 
ATOM   10885 C CA  . ILE D 1 199 ? 11.848  26.459  -14.654 1.00 32.32  ? 199 ILE D CA  1 
ATOM   10886 C C   . ILE D 1 199 ? 12.453  27.340  -15.730 1.00 28.90  ? 199 ILE D C   1 
ATOM   10887 O O   . ILE D 1 199 ? 12.508  28.563  -15.574 1.00 28.56  ? 199 ILE D O   1 
ATOM   10888 C CB  . ILE D 1 199 ? 10.323  26.676  -14.588 1.00 33.36  ? 199 ILE D CB  1 
ATOM   10889 C CG1 . ILE D 1 199 ? 9.675   25.716  -13.586 1.00 34.34  ? 199 ILE D CG1 1 
ATOM   10890 C CG2 . ILE D 1 199 ? 9.718   26.506  -15.970 1.00 34.58  ? 199 ILE D CG2 1 
ATOM   10891 C CD1 . ILE D 1 199 ? 8.266   26.120  -13.152 1.00 36.94  ? 199 ILE D CD1 1 
ATOM   10892 N N   . GLY D 1 200 ? 12.881  26.727  -16.832 1.00 35.93  ? 200 GLY D N   1 
ATOM   10893 C CA  . GLY D 1 200 ? 13.475  27.452  -17.943 1.00 30.08  ? 200 GLY D CA  1 
ATOM   10894 C C   . GLY D 1 200 ? 12.507  27.645  -19.095 1.00 26.98  ? 200 GLY D C   1 
ATOM   10895 O O   . GLY D 1 200 ? 11.640  26.815  -19.342 1.00 28.67  ? 200 GLY D O   1 
ATOM   10896 N N   . ILE D 1 201 ? 12.650  28.773  -19.787 1.00 28.32  ? 201 ILE D N   1 
ATOM   10897 C CA  . ILE D 1 201 ? 11.859  29.081  -20.973 1.00 24.64  ? 201 ILE D CA  1 
ATOM   10898 C C   . ILE D 1 201 ? 12.829  29.248  -22.130 1.00 26.81  ? 201 ILE D C   1 
ATOM   10899 O O   . ILE D 1 201 ? 13.765  30.052  -22.052 1.00 27.68  ? 201 ILE D O   1 
ATOM   10900 C CB  . ILE D 1 201 ? 11.006  30.344  -20.788 1.00 24.72  ? 201 ILE D CB  1 
ATOM   10901 C CG1 . ILE D 1 201 ? 10.058  30.187  -19.621 1.00 26.47  ? 201 ILE D CG1 1 
ATOM   10902 C CG2 . ILE D 1 201 ? 10.178  30.618  -22.004 1.00 20.96  ? 201 ILE D CG2 1 
ATOM   10903 C CD1 . ILE D 1 201 ? 9.487   31.487  -19.207 1.00 28.58  ? 201 ILE D CD1 1 
ATOM   10904 N N   . SER D 1 202 ? 12.618  28.489  -23.197 1.00 27.05  ? 202 SER D N   1 
ATOM   10905 C CA  . SER D 1 202 ? 13.589  28.458  -24.273 1.00 30.22  ? 202 SER D CA  1 
ATOM   10906 C C   . SER D 1 202 ? 12.903  28.468  -25.628 1.00 35.17  ? 202 SER D C   1 
ATOM   10907 O O   . SER D 1 202 ? 11.874  27.813  -25.828 1.00 31.01  ? 202 SER D O   1 
ATOM   10908 C CB  . SER D 1 202 ? 14.485  27.227  -24.170 1.00 31.26  ? 202 SER D CB  1 
ATOM   10909 O OG  . SER D 1 202 ? 15.457  27.239  -25.196 1.00 33.87  ? 202 SER D OG  1 
ATOM   10910 N N   . THR D 1 203 ? 13.492  29.227  -26.551 1.00 28.83  ? 203 THR D N   1 
ATOM   10911 C CA  . THR D 1 203 ? 13.195  29.055  -27.966 1.00 37.66  ? 203 THR D CA  1 
ATOM   10912 C C   . THR D 1 203 ? 13.971  27.894  -28.576 1.00 43.12  ? 203 THR D C   1 
ATOM   10913 O O   . THR D 1 203 ? 13.538  27.321  -29.585 1.00 47.55  ? 203 THR D O   1 
ATOM   10914 C CB  . THR D 1 203 ? 13.536  30.323  -28.744 1.00 35.83  ? 203 THR D CB  1 
ATOM   10915 O OG1 . THR D 1 203 ? 14.962  30.465  -28.823 1.00 31.49  ? 203 THR D OG1 1 
ATOM   10916 C CG2 . THR D 1 203 ? 12.954  31.541  -28.065 1.00 35.79  ? 203 THR D CG2 1 
ATOM   10917 N N   . SER D 1 204 ? 15.108  27.533  -27.992 1.00 41.16  ? 204 SER D N   1 
ATOM   10918 C CA  . SER D 1 204 ? 16.001  26.572  -28.640 1.00 46.44  ? 204 SER D CA  1 
ATOM   10919 C C   . SER D 1 204 ? 15.951  25.225  -27.910 1.00 45.28  ? 204 SER D C   1 
ATOM   10920 O O   . SER D 1 204 ? 16.532  25.096  -26.831 1.00 48.88  ? 204 SER D O   1 
ATOM   10921 C CB  . SER D 1 204 ? 17.441  27.127  -28.663 1.00 47.26  ? 204 SER D CB  1 
ATOM   10922 O OG  . SER D 1 204 ? 17.455  28.454  -29.150 1.00 43.68  ? 204 SER D OG  1 
ATOM   10923 N N   . PRO D 1 205 ? 15.274  24.200  -28.451 1.00 53.08  ? 205 PRO D N   1 
ATOM   10924 C CA  . PRO D 1 205 ? 15.008  23.001  -27.666 1.00 49.81  ? 205 PRO D CA  1 
ATOM   10925 C C   . PRO D 1 205 ? 16.241  22.224  -27.220 1.00 54.22  ? 205 PRO D C   1 
ATOM   10926 O O   . PRO D 1 205 ? 16.068  21.275  -26.433 1.00 53.30  ? 205 PRO D O   1 
ATOM   10927 C CB  . PRO D 1 205 ? 14.109  22.175  -28.565 1.00 50.61  ? 205 PRO D CB  1 
ATOM   10928 C CG  . PRO D 1 205 ? 14.346  22.680  -29.917 1.00 43.79  ? 205 PRO D CG  1 
ATOM   10929 C CD  . PRO D 1 205 ? 14.657  24.131  -29.746 1.00 52.67  ? 205 PRO D CD  1 
ATOM   10930 N N   . GLU D 1 206 ? 17.447  22.565  -27.682 1.00 54.95  ? 206 GLU D N   1 
ATOM   10931 C CA  . GLU D 1 206 ? 18.667  22.007  -27.109 1.00 58.71  ? 206 GLU D CA  1 
ATOM   10932 C C   . GLU D 1 206 ? 18.551  21.961  -25.587 1.00 65.14  ? 206 GLU D C   1 
ATOM   10933 O O   . GLU D 1 206 ? 18.538  22.998  -24.911 1.00 64.26  ? 206 GLU D O   1 
ATOM   10934 C CB  . GLU D 1 206 ? 19.900  22.802  -27.544 1.00 60.29  ? 206 GLU D CB  1 
ATOM   10935 C CG  . GLU D 1 206 ? 19.738  24.309  -27.436 1.00 62.25  ? 206 GLU D CG  1 
ATOM   10936 C CD  . GLU D 1 206 ? 20.369  24.926  -26.191 1.00 57.84  ? 206 GLU D CD  1 
ATOM   10937 O OE1 . GLU D 1 206 ? 20.791  24.185  -25.275 1.00 63.47  ? 206 GLU D OE1 1 
ATOM   10938 O OE2 . GLU D 1 206 ? 20.450  26.175  -26.149 1.00 50.12  ? 206 GLU D OE2 1 
ATOM   10939 N N   . SER D 1 207 ? 18.421  20.751  -25.030 1.00 65.27  ? 207 SER D N   1 
ATOM   10940 C CA  . SER D 1 207 ? 17.988  20.633  -23.642 1.00 60.04  ? 207 SER D CA  1 
ATOM   10941 C C   . SER D 1 207 ? 18.988  21.223  -22.655 1.00 64.82  ? 207 SER D C   1 
ATOM   10942 O O   . SER D 1 207 ? 18.679  21.294  -21.455 1.00 65.14  ? 207 SER D O   1 
ATOM   10943 C CB  . SER D 1 207 ? 17.721  19.163  -23.316 1.00 68.58  ? 207 SER D CB  1 
ATOM   10944 O OG  . SER D 1 207 ? 16.556  19.024  -22.517 1.00 73.30  ? 207 SER D OG  1 
ATOM   10945 N N   . SER D 1 208 ? 20.161  21.660  -23.133 1.00 67.04  ? 208 SER D N   1 
ATOM   10946 C CA  . SER D 1 208 ? 21.242  22.149  -22.283 1.00 63.30  ? 208 SER D CA  1 
ATOM   10947 C C   . SER D 1 208 ? 20.819  23.357  -21.468 1.00 52.59  ? 208 SER D C   1 
ATOM   10948 O O   . SER D 1 208 ? 21.256  24.483  -21.733 1.00 43.07  ? 208 SER D O   1 
ATOM   10949 C CB  . SER D 1 208 ? 22.478  22.502  -23.110 1.00 60.42  ? 208 SER D CB  1 
ATOM   10950 O OG  . SER D 1 208 ? 23.371  21.408  -23.137 1.00 65.62  ? 208 SER D OG  1 
ATOM   10951 N N   . PHE D 1 209 ? 19.993  23.112  -20.453 1.00 47.17  ? 209 PHE D N   1 
ATOM   10952 C CA  . PHE D 1 209 ? 19.513  24.137  -19.533 1.00 45.15  ? 209 PHE D CA  1 
ATOM   10953 C C   . PHE D 1 209 ? 19.853  23.707  -18.112 1.00 45.08  ? 209 PHE D C   1 
ATOM   10954 O O   . PHE D 1 209 ? 18.959  23.349  -17.329 1.00 39.62  ? 209 PHE D O   1 
ATOM   10955 C CB  . PHE D 1 209 ? 18.009  24.337  -19.694 1.00 45.09  ? 209 PHE D CB  1 
ATOM   10956 C CG  . PHE D 1 209 ? 17.578  25.761  -19.664 1.00 38.28  ? 209 PHE D CG  1 
ATOM   10957 C CD1 . PHE D 1 209 ? 18.037  26.617  -18.673 1.00 41.02  ? 209 PHE D CD1 1 
ATOM   10958 C CD2 . PHE D 1 209 ? 16.686  26.237  -20.595 1.00 33.23  ? 209 PHE D CD2 1 
ATOM   10959 C CE1 . PHE D 1 209 ? 17.626  27.936  -18.618 1.00 35.03  ? 209 PHE D CE1 1 
ATOM   10960 C CE2 . PHE D 1 209 ? 16.267  27.554  -20.549 1.00 39.96  ? 209 PHE D CE2 1 
ATOM   10961 C CZ  . PHE D 1 209 ? 16.742  28.407  -19.554 1.00 35.77  ? 209 PHE D CZ  1 
ATOM   10962 N N   . PRO D 1 210 ? 21.138  23.701  -17.755 1.00 38.61  ? 210 PRO D N   1 
ATOM   10963 C CA  . PRO D 1 210 ? 21.509  23.275  -16.403 1.00 44.26  ? 210 PRO D CA  1 
ATOM   10964 C C   . PRO D 1 210 ? 20.918  24.222  -15.375 1.00 49.24  ? 210 PRO D C   1 
ATOM   10965 O O   . PRO D 1 210 ? 20.811  25.435  -15.603 1.00 46.46  ? 210 PRO D O   1 
ATOM   10966 C CB  . PRO D 1 210 ? 23.041  23.325  -16.407 1.00 43.16  ? 210 PRO D CB  1 
ATOM   10967 C CG  . PRO D 1 210 ? 23.448  23.606  -17.819 1.00 44.89  ? 210 PRO D CG  1 
ATOM   10968 C CD  . PRO D 1 210 ? 22.287  24.199  -18.523 1.00 40.61  ? 210 PRO D CD  1 
ATOM   10969 N N   . GLY D 1 211 ? 20.510  23.648  -14.247 1.00 44.92  ? 211 GLY D N   1 
ATOM   10970 C CA  . GLY D 1 211 ? 19.920  24.408  -13.169 1.00 44.61  ? 211 GLY D CA  1 
ATOM   10971 C C   . GLY D 1 211 ? 18.417  24.539  -13.212 1.00 48.61  ? 211 GLY D C   1 
ATOM   10972 O O   . GLY D 1 211 ? 17.860  25.311  -12.420 1.00 48.60  ? 211 GLY D O   1 
ATOM   10973 N N   . THR D 1 212 ? 17.737  23.831  -14.110 1.00 41.36  ? 212 THR D N   1 
ATOM   10974 C CA  . THR D 1 212 ? 16.285  23.868  -14.179 1.00 44.08  ? 212 THR D CA  1 
ATOM   10975 C C   . THR D 1 212 ? 15.729  22.471  -13.974 1.00 42.71  ? 212 THR D C   1 
ATOM   10976 O O   . THR D 1 212 ? 16.383  21.477  -14.296 1.00 45.06  ? 212 THR D O   1 
ATOM   10977 C CB  . THR D 1 212 ? 15.768  24.396  -15.530 1.00 42.57  ? 212 THR D CB  1 
ATOM   10978 O OG1 . THR D 1 212 ? 16.175  23.503  -16.572 1.00 40.56  ? 212 THR D OG1 1 
ATOM   10979 C CG2 . THR D 1 212 ? 16.270  25.810  -15.822 1.00 32.53  ? 212 THR D CG2 1 
ATOM   10980 N N   . ARG D 1 213 ? 14.507  22.405  -13.443 1.00 41.94  ? 213 ARG D N   1 
ATOM   10981 C CA  . ARG D 1 213 ? 13.828  21.122  -13.330 1.00 44.02  ? 213 ARG D CA  1 
ATOM   10982 C C   . ARG D 1 213 ? 13.080  20.782  -14.610 1.00 47.16  ? 213 ARG D C   1 
ATOM   10983 O O   . ARG D 1 213 ? 12.890  19.602  -14.918 1.00 51.13  ? 213 ARG D O   1 
ATOM   10984 C CB  . ARG D 1 213 ? 12.864  21.123  -12.138 1.00 49.07  ? 213 ARG D CB  1 
ATOM   10985 C CG  . ARG D 1 213 ? 11.653  22.055  -12.268 1.00 50.02  ? 213 ARG D CG  1 
ATOM   10986 C CD  . ARG D 1 213 ? 10.505  21.617  -11.357 1.00 50.22  ? 213 ARG D CD  1 
ATOM   10987 N NE  . ARG D 1 213 ? 9.490   22.654  -11.184 1.00 58.76  ? 213 ARG D NE  1 
ATOM   10988 C CZ  . ARG D 1 213 ? 9.243   23.279  -10.037 1.00 55.04  ? 213 ARG D CZ  1 
ATOM   10989 N NH1 . ARG D 1 213 ? 9.964   23.047  -8.950  1.00 57.49  ? 213 ARG D NH1 1 
ATOM   10990 N NH2 . ARG D 1 213 ? 8.244   24.156  -9.975  1.00 53.35  ? 213 ARG D NH2 1 
ATOM   10991 N N   . GLU D 1 214 ? 12.657  21.792  -15.366 1.00 40.93  ? 214 GLU D N   1 
ATOM   10992 C CA  . GLU D 1 214 ? 11.975  21.554  -16.626 1.00 38.65  ? 214 GLU D CA  1 
ATOM   10993 C C   . GLU D 1 214 ? 12.109  22.793  -17.502 1.00 40.45  ? 214 GLU D C   1 
ATOM   10994 O O   . GLU D 1 214 ? 12.302  23.906  -17.004 1.00 40.74  ? 214 GLU D O   1 
ATOM   10995 C CB  . GLU D 1 214 ? 10.504  21.187  -16.403 1.00 37.64  ? 214 GLU D CB  1 
ATOM   10996 C CG  . GLU D 1 214 ? 9.643   22.311  -15.895 1.00 41.11  ? 214 GLU D CG  1 
ATOM   10997 C CD  . GLU D 1 214 ? 8.229   21.869  -15.628 1.00 43.45  ? 214 GLU D CD  1 
ATOM   10998 O OE1 . GLU D 1 214 ? 7.541   21.440  -16.586 1.00 42.51  ? 214 GLU D OE1 1 
ATOM   10999 O OE2 . GLU D 1 214 ? 7.812   21.942  -14.453 1.00 51.01  ? 214 GLU D OE2 1 
ATOM   11000 N N   . VAL D 1 215 ? 12.016  22.579  -18.812 1.00 38.35  ? 215 VAL D N   1 
ATOM   11001 C CA  . VAL D 1 215 ? 12.187  23.628  -19.809 1.00 36.66  ? 215 VAL D CA  1 
ATOM   11002 C C   . VAL D 1 215 ? 10.915  23.703  -20.642 1.00 37.58  ? 215 VAL D C   1 
ATOM   11003 O O   . VAL D 1 215 ? 10.383  22.671  -21.066 1.00 35.19  ? 215 VAL D O   1 
ATOM   11004 C CB  . VAL D 1 215 ? 13.413  23.369  -20.704 1.00 37.93  ? 215 VAL D CB  1 
ATOM   11005 C CG1 . VAL D 1 215 ? 13.563  24.476  -21.758 1.00 31.27  ? 215 VAL D CG1 1 
ATOM   11006 C CG2 . VAL D 1 215 ? 14.675  23.270  -19.852 1.00 35.27  ? 215 VAL D CG2 1 
ATOM   11007 N N   . LEU D 1 216 ? 10.436  24.917  -20.878 1.00 29.61  ? 216 LEU D N   1 
ATOM   11008 C CA  . LEU D 1 216 ? 9.214   25.152  -21.626 1.00 34.38  ? 216 LEU D CA  1 
ATOM   11009 C C   . LEU D 1 216 ? 9.554   25.844  -22.940 1.00 36.03  ? 216 LEU D C   1 
ATOM   11010 O O   . LEU D 1 216 ? 10.481  26.661  -23.001 1.00 32.08  ? 216 LEU D O   1 
ATOM   11011 C CB  . LEU D 1 216 ? 8.236   25.999  -20.811 1.00 35.12  ? 216 LEU D CB  1 
ATOM   11012 C CG  . LEU D 1 216 ? 7.903   25.443  -19.414 1.00 37.61  ? 216 LEU D CG  1 
ATOM   11013 C CD1 . LEU D 1 216 ? 6.854   26.303  -18.697 1.00 28.62  ? 216 LEU D CD1 1 
ATOM   11014 C CD2 . LEU D 1 216 ? 7.437   24.014  -19.525 1.00 32.47  ? 216 LEU D CD2 1 
ATOM   11015 N N   . ALA D 1 217 ? 8.817   25.496  -23.995 1.00 33.96  ? 217 ALA D N   1 
ATOM   11016 C CA  . ALA D 1 217 ? 9.028   26.106  -25.303 1.00 34.03  ? 217 ALA D CA  1 
ATOM   11017 C C   . ALA D 1 217 ? 8.382   27.482  -25.349 1.00 25.59  ? 217 ALA D C   1 
ATOM   11018 O O   . ALA D 1 217 ? 7.292   27.688  -24.813 1.00 24.32  ? 217 ALA D O   1 
ATOM   11019 C CB  . ALA D 1 217 ? 8.454   25.221  -26.411 1.00 37.27  ? 217 ALA D CB  1 
ATOM   11020 N N   . TYR D 1 218 ? 9.065   28.425  -25.980 1.00 29.59  ? 218 TYR D N   1 
ATOM   11021 C CA  . TYR D 1 218 ? 8.589   29.796  -26.042 1.00 34.18  ? 218 TYR D CA  1 
ATOM   11022 C C   . TYR D 1 218 ? 7.820   30.063  -27.329 1.00 28.46  ? 218 TYR D C   1 
ATOM   11023 O O   . TYR D 1 218 ? 8.097   29.475  -28.375 1.00 36.37  ? 218 TYR D O   1 
ATOM   11024 C CB  . TYR D 1 218 ? 9.734   30.808  -25.945 1.00 32.90  ? 218 TYR D CB  1 
ATOM   11025 C CG  . TYR D 1 218 ? 9.202   32.214  -25.999 1.00 32.48  ? 218 TYR D CG  1 
ATOM   11026 C CD1 . TYR D 1 218 ? 8.492   32.735  -24.929 1.00 31.91  ? 218 TYR D CD1 1 
ATOM   11027 C CD2 . TYR D 1 218 ? 9.336   32.992  -27.141 1.00 33.20  ? 218 TYR D CD2 1 
ATOM   11028 C CE1 . TYR D 1 218 ? 7.972   34.003  -24.966 1.00 32.68  ? 218 TYR D CE1 1 
ATOM   11029 C CE2 . TYR D 1 218 ? 8.815   34.282  -27.190 1.00 34.33  ? 218 TYR D CE2 1 
ATOM   11030 C CZ  . TYR D 1 218 ? 8.130   34.781  -26.094 1.00 36.25  ? 218 TYR D CZ  1 
ATOM   11031 O OH  . TYR D 1 218 ? 7.591   36.052  -26.114 1.00 33.47  ? 218 TYR D OH  1 
ATOM   11032 N N   . ALA D 1 219 ? 6.860   30.981  -27.230 1.00 32.71  ? 219 ALA D N   1 
ATOM   11033 C CA  . ALA D 1 219 ? 6.125   31.600  -28.324 1.00 33.42  ? 219 ALA D CA  1 
ATOM   11034 C C   . ALA D 1 219 ? 5.251   32.684  -27.725 1.00 35.63  ? 219 ALA D C   1 
ATOM   11035 O O   . ALA D 1 219 ? 4.720   32.508  -26.625 1.00 34.89  ? 219 ALA D O   1 
ATOM   11036 C CB  . ALA D 1 219 ? 5.257   30.582  -29.074 1.00 36.72  ? 219 ALA D CB  1 
ATOM   11037 N N   . ASN D 1 220 ? 5.095   33.796  -28.451 1.00 39.60  ? 220 ASN D N   1 
ATOM   11038 C CA  . ASN D 1 220 ? 4.228   34.869  -27.969 1.00 35.18  ? 220 ASN D CA  1 
ATOM   11039 C C   . ASN D 1 220 ? 2.842   34.341  -27.631 1.00 36.77  ? 220 ASN D C   1 
ATOM   11040 O O   . ASN D 1 220 ? 2.246   34.728  -26.620 1.00 33.98  ? 220 ASN D O   1 
ATOM   11041 C CB  . ASN D 1 220 ? 4.109   35.984  -29.008 1.00 33.02  ? 220 ASN D CB  1 
ATOM   11042 C CG  . ASN D 1 220 ? 5.394   36.758  -29.201 1.00 38.75  ? 220 ASN D CG  1 
ATOM   11043 O OD1 . ASN D 1 220 ? 6.338   36.633  -28.423 1.00 37.87  ? 220 ASN D OD1 1 
ATOM   11044 N ND2 . ASN D 1 220 ? 5.436   37.576  -30.255 1.00 41.17  ? 220 ASN D ND2 1 
ATOM   11045 N N   . ASP D 1 221 ? 2.308   33.454  -28.460 1.00 33.76  ? 221 ASP D N   1 
ATOM   11046 C CA  . ASP D 1 221 ? 0.939   33.030  -28.216 1.00 33.57  ? 221 ASP D CA  1 
ATOM   11047 C C   . ASP D 1 221 ? 0.844   32.022  -27.077 1.00 35.32  ? 221 ASP D C   1 
ATOM   11048 O O   . ASP D 1 221 ? -0.258  31.553  -26.773 1.00 35.04  ? 221 ASP D O   1 
ATOM   11049 C CB  . ASP D 1 221 ? 0.302   32.501  -29.522 1.00 36.80  ? 221 ASP D CB  1 
ATOM   11050 C CG  . ASP D 1 221 ? 0.884   31.171  -30.002 1.00 39.76  ? 221 ASP D CG  1 
ATOM   11051 O OD1 . ASP D 1 221 ? 1.781   30.601  -29.335 1.00 43.05  ? 221 ASP D OD1 1 
ATOM   11052 O OD2 . ASP D 1 221 ? 0.434   30.691  -31.077 1.00 39.83  ? 221 ASP D OD2 1 
ATOM   11053 N N   . GLN D 1 222 ? 1.971   31.687  -26.446 1.00 32.52  ? 222 GLN D N   1 
ATOM   11054 C CA  . GLN D 1 222 ? 1.992   30.917  -25.212 1.00 35.55  ? 222 GLN D CA  1 
ATOM   11055 C C   . GLN D 1 222 ? 2.239   31.785  -23.977 1.00 38.45  ? 222 GLN D C   1 
ATOM   11056 O O   . GLN D 1 222 ? 2.190   31.265  -22.857 1.00 35.61  ? 222 GLN D O   1 
ATOM   11057 C CB  . GLN D 1 222 ? 3.055   29.813  -25.291 1.00 35.86  ? 222 GLN D CB  1 
ATOM   11058 C CG  . GLN D 1 222 ? 2.698   28.684  -26.247 1.00 41.14  ? 222 GLN D CG  1 
ATOM   11059 C CD  . GLN D 1 222 ? 1.219   28.372  -26.218 1.00 40.92  ? 222 GLN D CD  1 
ATOM   11060 O OE1 . GLN D 1 222 ? 0.681   27.955  -25.192 1.00 52.56  ? 222 GLN D OE1 1 
ATOM   11061 N NE2 . GLN D 1 222 ? 0.541   28.609  -27.337 1.00 40.81  ? 222 GLN D NE2 1 
ATOM   11062 N N   . LEU D 1 223 ? 2.468   33.092  -24.159 1.00 37.40  ? 223 LEU D N   1 
ATOM   11063 C CA  . LEU D 1 223 ? 2.895   33.961  -23.061 1.00 36.22  ? 223 LEU D CA  1 
ATOM   11064 C C   . LEU D 1 223 ? 1.920   33.913  -21.886 1.00 38.70  ? 223 LEU D C   1 
ATOM   11065 O O   . LEU D 1 223 ? 2.344   33.867  -20.727 1.00 38.54  ? 223 LEU D O   1 
ATOM   11066 C CB  . LEU D 1 223 ? 3.052   35.388  -23.577 1.00 29.82  ? 223 LEU D CB  1 
ATOM   11067 C CG  . LEU D 1 223 ? 4.321   36.211  -23.358 1.00 41.47  ? 223 LEU D CG  1 
ATOM   11068 C CD1 . LEU D 1 223 ? 5.531   35.371  -22.998 1.00 33.26  ? 223 LEU D CD1 1 
ATOM   11069 C CD2 . LEU D 1 223 ? 4.622   37.062  -24.600 1.00 41.63  ? 223 LEU D CD2 1 
ATOM   11070 N N   . ASP D 1 224 ? 0.612   33.886  -22.162 1.00 33.64  ? 224 ASP D N   1 
ATOM   11071 C CA  . ASP D 1 224 ? -0.364  33.824  -21.076 1.00 34.19  ? 224 ASP D CA  1 
ATOM   11072 C C   . ASP D 1 224 ? -0.199  32.544  -20.268 1.00 37.49  ? 224 ASP D C   1 
ATOM   11073 O O   . ASP D 1 224 ? -0.148  32.574  -19.032 1.00 40.47  ? 224 ASP D O   1 
ATOM   11074 C CB  . ASP D 1 224 ? -1.786  33.914  -21.629 1.00 33.07  ? 224 ASP D CB  1 
ATOM   11075 C CG  . ASP D 1 224 ? -2.139  35.296  -22.129 1.00 41.50  ? 224 ASP D CG  1 
ATOM   11076 O OD1 . ASP D 1 224 ? -1.228  36.140  -22.255 1.00 43.85  ? 224 ASP D OD1 1 
ATOM   11077 O OD2 . ASP D 1 224 ? -3.333  35.534  -22.421 1.00 48.47  ? 224 ASP D OD2 1 
ATOM   11078 N N   . THR D 1 225 ? -0.125  31.400  -20.954 1.00 38.52  ? 225 THR D N   1 
ATOM   11079 C CA  . THR D 1 225 ? -0.053  30.117  -20.259 1.00 38.09  ? 225 THR D CA  1 
ATOM   11080 C C   . THR D 1 225 ? 1.285   29.935  -19.539 1.00 35.96  ? 225 THR D C   1 
ATOM   11081 O O   . THR D 1 225 ? 1.332   29.324  -18.466 1.00 35.35  ? 225 THR D O   1 
ATOM   11082 C CB  . THR D 1 225 ? -0.302  28.972  -21.245 1.00 39.06  ? 225 THR D CB  1 
ATOM   11083 O OG1 . THR D 1 225 ? 0.771   28.916  -22.198 1.00 43.53  ? 225 THR D OG1 1 
ATOM   11084 C CG2 . THR D 1 225 ? -1.612  29.186  -21.982 1.00 38.08  ? 225 THR D CG2 1 
ATOM   11085 N N   . LEU D 1 226 ? 2.378   30.445  -20.116 1.00 38.28  ? 226 LEU D N   1 
ATOM   11086 C CA  . LEU D 1 226 ? 3.679   30.402  -19.451 1.00 35.69  ? 226 LEU D CA  1 
ATOM   11087 C C   . LEU D 1 226 ? 3.653   31.160  -18.133 1.00 34.59  ? 226 LEU D C   1 
ATOM   11088 O O   . LEU D 1 226 ? 4.014   30.616  -17.084 1.00 36.86  ? 226 LEU D O   1 
ATOM   11089 C CB  . LEU D 1 226 ? 4.764   30.975  -20.357 1.00 33.23  ? 226 LEU D CB  1 
ATOM   11090 C CG  . LEU D 1 226 ? 4.982   30.268  -21.682 1.00 34.87  ? 226 LEU D CG  1 
ATOM   11091 C CD1 . LEU D 1 226 ? 5.731   31.185  -22.633 1.00 32.30  ? 226 LEU D CD1 1 
ATOM   11092 C CD2 . LEU D 1 226 ? 5.732   28.965  -21.448 1.00 32.89  ? 226 LEU D CD2 1 
ATOM   11093 N N   . ALA D 1 227 ? 3.241   32.431  -18.182 1.00 30.81  ? 227 ALA D N   1 
ATOM   11094 C CA  . ALA D 1 227 ? 3.153   33.266  -16.987 1.00 36.62  ? 227 ALA D CA  1 
ATOM   11095 C C   . ALA D 1 227 ? 2.328   32.603  -15.889 1.00 37.73  ? 227 ALA D C   1 
ATOM   11096 O O   . ALA D 1 227 ? 2.724   32.592  -14.719 1.00 33.43  ? 227 ALA D O   1 
ATOM   11097 C CB  . ALA D 1 227 ? 2.556   34.624  -17.352 1.00 29.87  ? 227 ALA D CB  1 
ATOM   11098 N N   . ASP D 1 228 ? 1.172   32.043  -16.254 1.00 38.12  ? 228 ASP D N   1 
ATOM   11099 C CA  . ASP D 1 228 ? 0.325   31.385  -15.268 1.00 37.75  ? 228 ASP D CA  1 
ATOM   11100 C C   . ASP D 1 228 ? 1.021   30.173  -14.671 1.00 38.78  ? 228 ASP D C   1 
ATOM   11101 O O   . ASP D 1 228 ? 0.943   29.933  -13.459 1.00 37.79  ? 228 ASP D O   1 
ATOM   11102 C CB  . ASP D 1 228 ? -0.995  30.961  -15.910 1.00 41.37  ? 228 ASP D CB  1 
ATOM   11103 C CG  . ASP D 1 228 ? -1.912  32.130  -16.185 1.00 43.88  ? 228 ASP D CG  1 
ATOM   11104 O OD1 . ASP D 1 228 ? -1.854  33.132  -15.436 1.00 45.36  ? 228 ASP D OD1 1 
ATOM   11105 O OD2 . ASP D 1 228 ? -2.680  32.055  -17.165 1.00 48.63  ? 228 ASP D OD2 1 
ATOM   11106 N N   . THR D 1 229 ? 1.704   29.396  -15.513 1.00 31.27  ? 229 THR D N   1 
ATOM   11107 C CA  . THR D 1 229 ? 2.316   28.163  -15.041 1.00 38.45  ? 229 THR D CA  1 
ATOM   11108 C C   . THR D 1 229 ? 3.485   28.449  -14.106 1.00 39.85  ? 229 THR D C   1 
ATOM   11109 O O   . THR D 1 229 ? 3.619   27.796  -13.064 1.00 38.24  ? 229 THR D O   1 
ATOM   11110 C CB  . THR D 1 229 ? 2.755   27.306  -16.230 1.00 38.41  ? 229 THR D CB  1 
ATOM   11111 O OG1 . THR D 1 229 ? 1.602   26.953  -17.000 1.00 42.31  ? 229 THR D OG1 1 
ATOM   11112 C CG2 . THR D 1 229 ? 3.436   26.031  -15.762 1.00 41.38  ? 229 THR D CG2 1 
ATOM   11113 N N   . LEU D 1 230 ? 4.329   29.431  -14.442 1.00 35.43  ? 230 LEU D N   1 
ATOM   11114 C CA  . LEU D 1 230 ? 5.430   29.759  -13.540 1.00 39.85  ? 230 LEU D CA  1 
ATOM   11115 C C   . LEU D 1 230 ? 4.908   30.317  -12.220 1.00 34.71  ? 230 LEU D C   1 
ATOM   11116 O O   . LEU D 1 230 ? 5.442   29.995  -11.154 1.00 35.93  ? 230 LEU D O   1 
ATOM   11117 C CB  . LEU D 1 230 ? 6.390   30.750  -14.197 1.00 30.84  ? 230 LEU D CB  1 
ATOM   11118 C CG  . LEU D 1 230 ? 6.939   30.397  -15.572 1.00 34.65  ? 230 LEU D CG  1 
ATOM   11119 C CD1 . LEU D 1 230 ? 8.045   31.378  -15.986 1.00 33.44  ? 230 LEU D CD1 1 
ATOM   11120 C CD2 . LEU D 1 230 ? 7.446   28.994  -15.574 1.00 32.22  ? 230 LEU D CD2 1 
ATOM   11121 N N   . TRP D 1 231 ? 3.839   31.117  -12.267 1.00 31.75  ? 231 TRP D N   1 
ATOM   11122 C CA  . TRP D 1 231 ? 3.363   31.780  -11.053 1.00 36.73  ? 231 TRP D CA  1 
ATOM   11123 C C   . TRP D 1 231 ? 2.774   30.787  -10.055 1.00 37.25  ? 231 TRP D C   1 
ATOM   11124 O O   . TRP D 1 231 ? 3.058   30.864  -8.855  1.00 41.25  ? 231 TRP D O   1 
ATOM   11125 C CB  . TRP D 1 231 ? 2.335   32.866  -11.383 1.00 34.58  ? 231 TRP D CB  1 
ATOM   11126 C CG  . TRP D 1 231 ? 1.941   33.607  -10.127 1.00 36.65  ? 231 TRP D CG  1 
ATOM   11127 C CD1 . TRP D 1 231 ? 0.803   33.433  -9.383  1.00 27.90  ? 231 TRP D CD1 1 
ATOM   11128 C CD2 . TRP D 1 231 ? 2.725   34.582  -9.438  1.00 33.84  ? 231 TRP D CD2 1 
ATOM   11129 N NE1 . TRP D 1 231 ? 0.828   34.252  -8.287  1.00 36.27  ? 231 TRP D NE1 1 
ATOM   11130 C CE2 . TRP D 1 231 ? 1.999   34.966  -8.291  1.00 35.09  ? 231 TRP D CE2 1 
ATOM   11131 C CE3 . TRP D 1 231 ? 3.974   35.173  -9.681  1.00 35.91  ? 231 TRP D CE3 1 
ATOM   11132 C CZ2 . TRP D 1 231 ? 2.472   35.925  -7.396  1.00 37.86  ? 231 TRP D CZ2 1 
ATOM   11133 C CZ3 . TRP D 1 231 ? 4.447   36.125  -8.789  1.00 35.40  ? 231 TRP D CZ3 1 
ATOM   11134 C CH2 . TRP D 1 231 ? 3.691   36.496  -7.661  1.00 34.87  ? 231 TRP D CH2 1 
ATOM   11135 N N   . SER D 1 232 ? 1.946   29.860  -10.515 1.00 40.22  ? 232 SER D N   1 
ATOM   11136 C CA  . SER D 1 232 ? 1.329   28.920  -9.587  1.00 36.83  ? 232 SER D CA  1 
ATOM   11137 C C   . SER D 1 232 ? 2.282   27.823  -9.140  1.00 40.37  ? 232 SER D C   1 
ATOM   11138 O O   . SER D 1 232 ? 2.056   27.216  -8.084  1.00 45.37  ? 232 SER D O   1 
ATOM   11139 C CB  . SER D 1 232 ? 0.090   28.304  -10.228 1.00 35.49  ? 232 SER D CB  1 
ATOM   11140 O OG  . SER D 1 232 ? 0.415   27.860  -11.525 1.00 40.80  ? 232 SER D OG  1 
ATOM   11141 N N   . GLN D 1 233 ? 3.344   27.557  -9.901  1.00 38.48  ? 233 GLN D N   1 
ATOM   11142 C CA  . GLN D 1 233 ? 4.269   26.496  -9.532  1.00 40.32  ? 233 GLN D CA  1 
ATOM   11143 C C   . GLN D 1 233 ? 5.384   26.955  -8.599  1.00 35.98  ? 233 GLN D C   1 
ATOM   11144 O O   . GLN D 1 233 ? 5.963   26.124  -7.895  1.00 35.47  ? 233 GLN D O   1 
ATOM   11145 C CB  . GLN D 1 233 ? 4.891   25.870  -10.787 1.00 43.96  ? 233 GLN D CB  1 
ATOM   11146 C CG  . GLN D 1 233 ? 4.279   24.517  -11.158 1.00 49.23  ? 233 GLN D CG  1 
ATOM   11147 C CD  . GLN D 1 233 ? 4.826   23.946  -12.457 1.00 55.69  ? 233 GLN D CD  1 
ATOM   11148 O OE1 . GLN D 1 233 ? 6.038   23.881  -12.656 1.00 61.94  ? 233 GLN D OE1 1 
ATOM   11149 N NE2 . GLN D 1 233 ? 3.930   23.533  -13.349 1.00 53.34  ? 233 GLN D NE2 1 
ATOM   11150 N N   . LEU D 1 234 ? 5.699   28.244  -8.563  1.00 36.44  ? 234 LEU D N   1 
ATOM   11151 C CA  . LEU D 1 234 ? 6.873   28.699  -7.837  1.00 38.95  ? 234 LEU D CA  1 
ATOM   11152 C C   . LEU D 1 234 ? 6.563   29.655  -6.688  1.00 38.39  ? 234 LEU D C   1 
ATOM   11153 O O   . LEU D 1 234 ? 7.492   30.081  -5.996  1.00 36.83  ? 234 LEU D O   1 
ATOM   11154 C CB  . LEU D 1 234 ? 7.856   29.357  -8.809  1.00 37.41  ? 234 LEU D CB  1 
ATOM   11155 C CG  . LEU D 1 234 ? 8.411   28.516  -9.963  1.00 35.40  ? 234 LEU D CG  1 
ATOM   11156 C CD1 . LEU D 1 234 ? 9.102   29.413  -10.976 1.00 30.89  ? 234 LEU D CD1 1 
ATOM   11157 C CD2 . LEU D 1 234 ? 9.379   27.468  -9.442  1.00 38.05  ? 234 LEU D CD2 1 
ATOM   11158 N N   . THR D 1 235 ? 5.297   29.996  -6.458  1.00 40.14  ? 235 THR D N   1 
ATOM   11159 C CA  . THR D 1 235 ? 4.885   30.783  -5.303  1.00 45.26  ? 235 THR D CA  1 
ATOM   11160 C C   . THR D 1 235 ? 4.013   29.937  -4.388  1.00 43.02  ? 235 THR D C   1 
ATOM   11161 O O   . THR D 1 235 ? 3.374   28.980  -4.832  1.00 46.27  ? 235 THR D O   1 
ATOM   11162 C CB  . THR D 1 235 ? 4.106   32.043  -5.714  1.00 36.55  ? 235 THR D CB  1 
ATOM   11163 O OG1 . THR D 1 235 ? 2.843   31.670  -6.277  1.00 32.76  ? 235 THR D OG1 1 
ATOM   11164 C CG2 . THR D 1 235 ? 4.881   32.845  -6.713  1.00 38.88  ? 235 THR D CG2 1 
ATOM   11165 N N   . ASP D 1 236 ? 4.004   30.296  -3.105  1.00 45.81  ? 236 ASP D N   1 
ATOM   11166 C CA  . ASP D 1 236 ? 3.065   29.751  -2.119  1.00 52.19  ? 236 ASP D CA  1 
ATOM   11167 C C   . ASP D 1 236 ? 2.686   30.879  -1.162  1.00 50.41  ? 236 ASP D C   1 
ATOM   11168 O O   . ASP D 1 236 ? 2.933   32.055  -1.440  1.00 50.31  ? 236 ASP D O   1 
ATOM   11169 C CB  . ASP D 1 236 ? 3.643   28.526  -1.386  1.00 49.98  ? 236 ASP D CB  1 
ATOM   11170 C CG  . ASP D 1 236 ? 5.125   28.676  -1.026  1.00 54.31  ? 236 ASP D CG  1 
ATOM   11171 O OD1 . ASP D 1 236 ? 5.557   29.770  -0.593  1.00 53.51  ? 236 ASP D OD1 1 
ATOM   11172 O OD2 . ASP D 1 236 ? 5.865   27.679  -1.177  1.00 54.09  ? 236 ASP D OD2 1 
ATOM   11173 N N   . THR D 1 237 ? 2.077   30.518  -0.029  1.00 55.36  ? 237 THR D N   1 
ATOM   11174 C CA  . THR D 1 237 ? 1.628   31.513  0.948   1.00 54.36  ? 237 THR D CA  1 
ATOM   11175 C C   . THR D 1 237 ? 2.751   32.469  1.348   1.00 54.24  ? 237 THR D C   1 
ATOM   11176 O O   . THR D 1 237 ? 2.564   33.691  1.382   1.00 47.03  ? 237 THR D O   1 
ATOM   11177 C CB  . THR D 1 237 ? 1.076   30.810  2.194   1.00 53.97  ? 237 THR D CB  1 
ATOM   11178 O OG1 . THR D 1 237 ? 2.166   30.428  3.048   1.00 55.61  ? 237 THR D OG1 1 
ATOM   11179 C CG2 . THR D 1 237 ? 0.294   29.570  1.813   1.00 48.62  ? 237 THR D CG2 1 
ATOM   11180 N N   . GLN D 1 238 ? 3.931   31.921  1.663   1.00 57.08  ? 238 GLN D N   1 
ATOM   11181 C CA  . GLN D 1 238 ? 5.044   32.702  2.192   1.00 55.45  ? 238 GLN D CA  1 
ATOM   11182 C C   . GLN D 1 238 ? 5.895   33.349  1.110   1.00 53.73  ? 238 GLN D C   1 
ATOM   11183 O O   . GLN D 1 238 ? 6.593   34.330  1.394   1.00 53.02  ? 238 GLN D O   1 
ATOM   11184 C CB  . GLN D 1 238 ? 5.954   31.818  3.058   1.00 58.61  ? 238 GLN D CB  1 
ATOM   11185 C CG  . GLN D 1 238 ? 7.202   31.308  2.315   1.00 62.53  ? 238 GLN D CG  1 
ATOM   11186 C CD  . GLN D 1 238 ? 7.792   30.037  2.905   1.00 67.34  ? 238 GLN D CD  1 
ATOM   11187 O OE1 . GLN D 1 238 ? 7.276   29.489  3.879   1.00 70.24  ? 238 GLN D OE1 1 
ATOM   11188 N NE2 . GLN D 1 238 ? 8.882   29.558  2.306   1.00 69.41  ? 238 GLN D NE2 1 
ATOM   11189 N N   . ASN D 1 239 ? 5.866   32.816  -0.106  1.00 53.16  ? 239 ASN D N   1 
ATOM   11190 C CA  . ASN D 1 239 ? 6.733   33.248  -1.199  1.00 52.50  ? 239 ASN D CA  1 
ATOM   11191 C C   . ASN D 1 239 ? 5.857   33.922  -2.248  1.00 44.48  ? 239 ASN D C   1 
ATOM   11192 O O   . ASN D 1 239 ? 5.185   33.252  -3.036  1.00 44.19  ? 239 ASN D O   1 
ATOM   11193 C CB  . ASN D 1 239 ? 7.505   32.062  -1.770  1.00 50.33  ? 239 ASN D CB  1 
ATOM   11194 C CG  . ASN D 1 239 ? 8.920   31.978  -1.229  1.00 54.76  ? 239 ASN D CG  1 
ATOM   11195 O OD1 . ASN D 1 239 ? 9.139   32.068  -0.017  1.00 55.45  ? 239 ASN D OD1 1 
ATOM   11196 N ND2 . ASN D 1 239 ? 9.891   31.793  -2.128  1.00 52.45  ? 239 ASN D ND2 1 
ATOM   11197 N N   . GLN D 1 240 ? 5.852   35.250  -2.243  1.00 42.83  ? 240 GLN D N   1 
ATOM   11198 C CA  . GLN D 1 240 ? 5.009   36.024  -3.140  1.00 36.84  ? 240 GLN D CA  1 
ATOM   11199 C C   . GLN D 1 240 ? 5.827   36.795  -4.165  1.00 42.83  ? 240 GLN D C   1 
ATOM   11200 O O   . GLN D 1 240 ? 5.311   37.727  -4.788  1.00 47.29  ? 240 GLN D O   1 
ATOM   11201 C CB  . GLN D 1 240 ? 4.122   36.968  -2.334  1.00 46.67  ? 240 GLN D CB  1 
ATOM   11202 C CG  . GLN D 1 240 ? 2.843   36.321  -1.834  1.00 46.39  ? 240 GLN D CG  1 
ATOM   11203 C CD  . GLN D 1 240 ? 1.984   35.818  -2.977  1.00 50.13  ? 240 GLN D CD  1 
ATOM   11204 O OE1 . GLN D 1 240 ? 1.702   34.619  -3.081  1.00 36.47  ? 240 GLN D OE1 1 
ATOM   11205 N NE2 . GLN D 1 240 ? 1.597   36.736  -3.874  1.00 41.94  ? 240 GLN D NE2 1 
ATOM   11206 N N   . PHE D 1 241 ? 7.100   36.437  -4.340  1.00 38.21  ? 241 PHE D N   1 
ATOM   11207 C CA  . PHE D 1 241 ? 7.931   36.956  -5.413  1.00 32.30  ? 241 PHE D CA  1 
ATOM   11208 C C   . PHE D 1 241 ? 8.416   35.799  -6.271  1.00 34.82  ? 241 PHE D C   1 
ATOM   11209 O O   . PHE D 1 241 ? 8.611   34.679  -5.783  1.00 35.34  ? 241 PHE D O   1 
ATOM   11210 C CB  . PHE D 1 241 ? 9.171   37.698  -4.899  1.00 32.77  ? 241 PHE D CB  1 
ATOM   11211 C CG  . PHE D 1 241 ? 8.898   39.019  -4.235  1.00 37.64  ? 241 PHE D CG  1 
ATOM   11212 C CD1 . PHE D 1 241 ? 7.968   39.903  -4.743  1.00 38.96  ? 241 PHE D CD1 1 
ATOM   11213 C CD2 . PHE D 1 241 ? 9.639   39.401  -3.121  1.00 35.43  ? 241 PHE D CD2 1 
ATOM   11214 C CE1 . PHE D 1 241 ? 7.756   41.137  -4.129  1.00 36.22  ? 241 PHE D CE1 1 
ATOM   11215 C CE2 . PHE D 1 241 ? 9.427   40.616  -2.505  1.00 35.12  ? 241 PHE D CE2 1 
ATOM   11216 C CZ  . PHE D 1 241 ? 8.482   41.490  -3.015  1.00 33.52  ? 241 PHE D CZ  1 
ATOM   11217 N N   . ILE D 1 242 ? 8.652   36.089  -7.544  1.00 29.84  ? 242 ILE D N   1 
ATOM   11218 C CA  . ILE D 1 242 ? 9.372   35.194  -8.435  1.00 32.66  ? 242 ILE D CA  1 
ATOM   11219 C C   . ILE D 1 242 ? 10.416  36.028  -9.146  1.00 34.66  ? 242 ILE D C   1 
ATOM   11220 O O   . ILE D 1 242 ? 10.191  37.213  -9.416  1.00 35.23  ? 242 ILE D O   1 
ATOM   11221 C CB  . ILE D 1 242 ? 8.422   34.494  -9.430  1.00 36.05  ? 242 ILE D CB  1 
ATOM   11222 C CG1 . ILE D 1 242 ? 7.800   33.258  -8.785  1.00 32.50  ? 242 ILE D CG1 1 
ATOM   11223 C CG2 . ILE D 1 242 ? 9.116   34.106  -10.741 1.00 34.41  ? 242 ILE D CG2 1 
ATOM   11224 C CD1 . ILE D 1 242 ? 7.019   32.466  -9.781  1.00 41.41  ? 242 ILE D CD1 1 
ATOM   11225 N N   . THR D 1 243 ? 11.574  35.430  -9.400  1.00 28.00  ? 243 THR D N   1 
ATOM   11226 C CA  . THR D 1 243 ? 12.619  36.067  -10.184 1.00 32.71  ? 243 THR D CA  1 
ATOM   11227 C C   . THR D 1 243 ? 12.565  35.534  -11.612 1.00 28.14  ? 243 THR D C   1 
ATOM   11228 O O   . THR D 1 243 ? 12.340  34.343  -11.827 1.00 31.06  ? 243 THR D O   1 
ATOM   11229 C CB  . THR D 1 243 ? 13.993  35.838  -9.541  1.00 36.05  ? 243 THR D CB  1 
ATOM   11230 O OG1 . THR D 1 243 ? 14.171  36.767  -8.457  1.00 36.78  ? 243 THR D OG1 1 
ATOM   11231 C CG2 . THR D 1 243 ? 15.083  36.046  -10.513 1.00 35.57  ? 243 THR D CG2 1 
ATOM   11232 N N   . VAL D 1 244 ? 12.706  36.439  -12.579 1.00 27.28  ? 244 VAL D N   1 
ATOM   11233 C CA  . VAL D 1 244 ? 12.634  36.133  -14.003 1.00 29.54  ? 244 VAL D CA  1 
ATOM   11234 C C   . VAL D 1 244 ? 13.785  36.846  -14.678 1.00 29.86  ? 244 VAL D C   1 
ATOM   11235 O O   . VAL D 1 244 ? 13.827  38.085  -14.676 1.00 23.02  ? 244 VAL D O   1 
ATOM   11236 C CB  . VAL D 1 244 ? 11.308  36.573  -14.648 1.00 29.00  ? 244 VAL D CB  1 
ATOM   11237 C CG1 . VAL D 1 244 ? 11.264  36.077  -16.086 1.00 26.78  ? 244 VAL D CG1 1 
ATOM   11238 C CG2 . VAL D 1 244 ? 10.095  36.035  -13.854 1.00 28.89  ? 244 VAL D CG2 1 
ATOM   11239 N N   . GLU D 1 245 ? 14.686  36.071  -15.295 1.00 23.39  ? 245 GLU D N   1 
ATOM   11240 C CA  . GLU D 1 245 ? 15.991  36.566  -15.695 1.00 28.87  ? 245 GLU D CA  1 
ATOM   11241 C C   . GLU D 1 245 ? 16.376  36.059  -17.077 1.00 29.22  ? 245 GLU D C   1 
ATOM   11242 O O   . GLU D 1 245 ? 16.001  34.957  -17.476 1.00 29.63  ? 245 GLU D O   1 
ATOM   11243 C CB  . GLU D 1 245 ? 17.062  36.123  -14.693 1.00 27.09  ? 245 GLU D CB  1 
ATOM   11244 C CG  . GLU D 1 245 ? 16.923  36.752  -13.328 1.00 36.90  ? 245 GLU D CG  1 
ATOM   11245 C CD  . GLU D 1 245 ? 17.834  36.105  -12.286 1.00 39.09  ? 245 GLU D CD  1 
ATOM   11246 O OE1 . GLU D 1 245 ? 17.987  34.867  -12.331 1.00 39.42  ? 245 GLU D OE1 1 
ATOM   11247 O OE2 . GLU D 1 245 ? 18.388  36.837  -11.427 1.00 36.09  ? 245 GLU D OE2 1 
ATOM   11248 N N   . THR D 1 246 ? 17.173  36.855  -17.780 1.00 27.30  ? 246 THR D N   1 
ATOM   11249 C CA  . THR D 1 246 ? 17.817  36.375  -18.995 1.00 31.55  ? 246 THR D CA  1 
ATOM   11250 C C   . THR D 1 246 ? 18.856  35.317  -18.646 1.00 36.10  ? 246 THR D C   1 
ATOM   11251 O O   . THR D 1 246 ? 19.676  35.504  -17.742 1.00 36.57  ? 246 THR D O   1 
ATOM   11252 C CB  . THR D 1 246 ? 18.471  37.533  -19.736 1.00 30.86  ? 246 THR D CB  1 
ATOM   11253 O OG1 . THR D 1 246 ? 17.450  38.408  -20.243 1.00 33.35  ? 246 THR D OG1 1 
ATOM   11254 C CG2 . THR D 1 246 ? 19.357  37.031  -20.865 1.00 28.13  ? 246 THR D CG2 1 
ATOM   11255 N N   . TYR D 1 247 ? 18.814  34.198  -19.353 1.00 32.34  ? 247 TYR D N   1 
ATOM   11256 C CA  . TYR D 1 247 ? 19.732  33.094  -19.128 1.00 28.20  ? 247 TYR D CA  1 
ATOM   11257 C C   . TYR D 1 247 ? 20.777  33.066  -20.232 1.00 35.50  ? 247 TYR D C   1 
ATOM   11258 O O   . TYR D 1 247 ? 20.428  33.095  -21.416 1.00 37.71  ? 247 TYR D O   1 
ATOM   11259 C CB  . TYR D 1 247 ? 18.960  31.780  -19.092 1.00 34.72  ? 247 TYR D CB  1 
ATOM   11260 C CG  . TYR D 1 247 ? 19.799  30.583  -18.775 1.00 32.67  ? 247 TYR D CG  1 
ATOM   11261 C CD1 . TYR D 1 247 ? 20.028  30.209  -17.460 1.00 31.41  ? 247 TYR D CD1 1 
ATOM   11262 C CD2 . TYR D 1 247 ? 20.353  29.813  -19.794 1.00 33.75  ? 247 TYR D CD2 1 
ATOM   11263 C CE1 . TYR D 1 247 ? 20.795  29.102  -17.161 1.00 37.04  ? 247 TYR D CE1 1 
ATOM   11264 C CE2 . TYR D 1 247 ? 21.113  28.696  -19.507 1.00 34.75  ? 247 TYR D CE2 1 
ATOM   11265 C CZ  . TYR D 1 247 ? 21.333  28.347  -18.194 1.00 39.61  ? 247 TYR D CZ  1 
ATOM   11266 O OH  . TYR D 1 247 ? 22.097  27.241  -17.907 1.00 47.33  ? 247 TYR D OH  1 
ATOM   11267 N N   . HIS D 1 248 ? 22.052  33.003  -19.848 1.00 37.77  ? 248 HIS D N   1 
ATOM   11268 C CA  . HIS D 1 248 ? 23.157  32.975  -20.795 1.00 36.06  ? 248 HIS D CA  1 
ATOM   11269 C C   . HIS D 1 248 ? 23.752  31.578  -20.870 1.00 39.88  ? 248 HIS D C   1 
ATOM   11270 O O   . HIS D 1 248 ? 23.957  30.920  -19.844 1.00 40.47  ? 248 HIS D O   1 
ATOM   11271 C CB  . HIS D 1 248 ? 24.245  33.987  -20.420 1.00 31.30  ? 248 HIS D CB  1 
ATOM   11272 C CG  . HIS D 1 248 ? 23.786  35.407  -20.485 1.00 34.93  ? 248 HIS D CG  1 
ATOM   11273 N ND1 . HIS D 1 248 ? 23.804  36.141  -21.651 1.00 37.94  ? 248 HIS D ND1 1 
ATOM   11274 C CD2 . HIS D 1 248 ? 23.271  36.223  -19.536 1.00 36.63  ? 248 HIS D CD2 1 
ATOM   11275 C CE1 . HIS D 1 248 ? 23.334  37.354  -21.415 1.00 35.73  ? 248 HIS D CE1 1 
ATOM   11276 N NE2 . HIS D 1 248 ? 23.001  37.430  -20.139 1.00 36.78  ? 248 HIS D NE2 1 
ATOM   11277 N N   . ARG D 1 249 ? 23.992  31.121  -22.098 1.00 43.46  ? 249 ARG D N   1 
ATOM   11278 C CA  . ARG D 1 249 ? 24.859  29.976  -22.307 1.00 38.87  ? 249 ARG D CA  1 
ATOM   11279 C C   . ARG D 1 249 ? 26.252  30.369  -21.855 1.00 39.65  ? 249 ARG D C   1 
ATOM   11280 O O   . ARG D 1 249 ? 26.740  31.453  -22.188 1.00 48.41  ? 249 ARG D O   1 
ATOM   11281 C CB  . ARG D 1 249 ? 24.853  29.551  -23.776 1.00 39.21  ? 249 ARG D CB  1 
ATOM   11282 C CG  . ARG D 1 249 ? 23.460  29.455  -24.379 1.00 46.70  ? 249 ARG D CG  1 
ATOM   11283 C CD  . ARG D 1 249 ? 23.490  29.615  -25.890 1.00 51.16  ? 249 ARG D CD  1 
ATOM   11284 N NE  . ARG D 1 249 ? 22.288  29.086  -26.528 1.00 54.17  ? 249 ARG D NE  1 
ATOM   11285 C CZ  . ARG D 1 249 ? 21.143  29.749  -26.630 1.00 53.69  ? 249 ARG D CZ  1 
ATOM   11286 N NH1 . ARG D 1 249 ? 21.008  30.974  -26.147 1.00 46.63  ? 249 ARG D NH1 1 
ATOM   11287 N NH2 . ARG D 1 249 ? 20.106  29.169  -27.238 1.00 55.01  ? 249 ARG D NH2 1 
ATOM   11288 N N   . ALA D 1 250 ? 26.882  29.518  -21.067 1.00 34.19  ? 250 ALA D N   1 
ATOM   11289 C CA  . ALA D 1 250 ? 28.081  29.925  -20.358 1.00 43.22  ? 250 ALA D CA  1 
ATOM   11290 C C   . ALA D 1 250 ? 29.211  28.958  -20.642 1.00 45.47  ? 250 ALA D C   1 
ATOM   11291 O O   . ALA D 1 250 ? 29.018  27.738  -20.616 1.00 40.83  ? 250 ALA D O   1 
ATOM   11292 C CB  . ALA D 1 250 ? 27.831  30.006  -18.851 1.00 41.63  ? 250 ALA D CB  1 
ATOM   11293 N N   . ASP D 1 251 ? 30.386  29.517  -20.912 1.00 48.14  ? 251 ASP D N   1 
ATOM   11294 C CA  . ASP D 1 251 ? 31.616  28.746  -20.945 1.00 49.55  ? 251 ASP D CA  1 
ATOM   11295 C C   . ASP D 1 251 ? 31.883  28.122  -19.578 1.00 49.23  ? 251 ASP D C   1 
ATOM   11296 O O   . ASP D 1 251 ? 31.799  26.901  -19.420 1.00 49.66  ? 251 ASP D O   1 
ATOM   11297 C CB  . ASP D 1 251 ? 32.769  29.647  -21.384 1.00 47.95  ? 251 ASP D CB  1 
ATOM   11298 C CG  . ASP D 1 251 ? 33.934  28.871  -21.925 1.00 55.51  ? 251 ASP D CG  1 
ATOM   11299 O OD1 . ASP D 1 251 ? 33.846  27.621  -21.933 1.00 58.50  ? 251 ASP D OD1 1 
ATOM   11300 O OD2 . ASP D 1 251 ? 34.927  29.508  -22.343 1.00 57.22  ? 251 ASP D OD2 1 
ATOM   11301 N N   . GLN D 1 252 ? 32.157  28.953  -18.577 1.00 49.84  ? 252 GLN D N   1 
ATOM   11302 C CA  . GLN D 1 252 ? 32.602  28.504  -17.262 1.00 45.93  ? 252 GLN D CA  1 
ATOM   11303 C C   . GLN D 1 252 ? 31.509  28.769  -16.237 1.00 40.56  ? 252 GLN D C   1 
ATOM   11304 O O   . GLN D 1 252 ? 31.047  29.906  -16.106 1.00 41.31  ? 252 GLN D O   1 
ATOM   11305 C CB  . GLN D 1 252 ? 33.895  29.221  -16.874 1.00 45.68  ? 252 GLN D CB  1 
ATOM   11306 C CG  . GLN D 1 252 ? 34.681  29.758  -18.093 1.00 47.74  ? 252 GLN D CG  1 
ATOM   11307 C CD  . GLN D 1 252 ? 35.778  30.748  -17.726 1.00 42.60  ? 252 GLN D CD  1 
ATOM   11308 O OE1 . GLN D 1 252 ? 36.185  30.848  -16.567 1.00 40.84  ? 252 GLN D OE1 1 
ATOM   11309 N NE2 . GLN D 1 252 ? 36.258  31.493  -18.719 1.00 46.61  ? 252 GLN D NE2 1 
ATOM   11310 N N   . ARG D 1 253 ? 31.081  27.721  -15.537 1.00 42.41  ? 253 ARG D N   1 
ATOM   11311 C CA  . ARG D 1 253 ? 30.193  27.838  -14.384 1.00 37.38  ? 253 ARG D CA  1 
ATOM   11312 C C   . ARG D 1 253 ? 31.001  27.606  -13.112 1.00 38.98  ? 253 ARG D C   1 
ATOM   11313 O O   . ARG D 1 253 ? 31.720  26.611  -13.004 1.00 41.55  ? 253 ARG D O   1 
ATOM   11314 C CB  . ARG D 1 253 ? 29.043  26.835  -14.468 1.00 42.65  ? 253 ARG D CB  1 
ATOM   11315 C CG  . ARG D 1 253 ? 27.921  27.300  -15.374 1.00 45.07  ? 253 ARG D CG  1 
ATOM   11316 C CD  . ARG D 1 253 ? 26.921  26.199  -15.665 1.00 46.80  ? 253 ARG D CD  1 
ATOM   11317 N NE  . ARG D 1 253 ? 26.199  26.444  -16.911 1.00 48.03  ? 253 ARG D NE  1 
ATOM   11318 C CZ  . ARG D 1 253 ? 25.346  27.442  -17.112 1.00 52.06  ? 253 ARG D CZ  1 
ATOM   11319 N NH1 . ARG D 1 253 ? 25.018  28.282  -16.142 1.00 50.15  ? 253 ARG D NH1 1 
ATOM   11320 N NH2 . ARG D 1 253 ? 24.812  27.604  -18.319 1.00 48.99  ? 253 ARG D NH2 1 
ATOM   11321 N N   . PHE D 1 254 ? 30.893  28.529  -12.157 1.00 34.44  ? 254 PHE D N   1 
ATOM   11322 C CA  . PHE D 1 254 ? 31.746  28.507  -10.979 1.00 27.94  ? 254 PHE D CA  1 
ATOM   11323 C C   . PHE D 1 254 ? 30.951  28.966  -9.768  1.00 28.61  ? 254 PHE D C   1 
ATOM   11324 O O   . PHE D 1 254 ? 29.901  29.591  -9.898  1.00 27.61  ? 254 PHE D O   1 
ATOM   11325 C CB  . PHE D 1 254 ? 32.980  29.405  -11.172 1.00 27.54  ? 254 PHE D CB  1 
ATOM   11326 C CG  . PHE D 1 254 ? 32.667  30.889  -11.172 1.00 29.53  ? 254 PHE D CG  1 
ATOM   11327 C CD1 . PHE D 1 254 ? 32.566  31.599  -9.974  1.00 22.54  ? 254 PHE D CD1 1 
ATOM   11328 C CD2 . PHE D 1 254 ? 32.488  31.568  -12.366 1.00 27.08  ? 254 PHE D CD2 1 
ATOM   11329 C CE1 . PHE D 1 254 ? 32.281  32.960  -9.960  1.00 28.50  ? 254 PHE D CE1 1 
ATOM   11330 C CE2 . PHE D 1 254 ? 32.207  32.935  -12.368 1.00 29.81  ? 254 PHE D CE2 1 
ATOM   11331 C CZ  . PHE D 1 254 ? 32.100  33.633  -11.158 1.00 30.40  ? 254 PHE D CZ  1 
ATOM   11332 N N   . PHE D 1 255 ? 31.480  28.670  -8.584  1.00 27.90  ? 255 PHE D N   1 
ATOM   11333 C CA  . PHE D 1 255 ? 31.069  29.384  -7.385  1.00 27.01  ? 255 PHE D CA  1 
ATOM   11334 C C   . PHE D 1 255 ? 32.273  29.517  -6.467  1.00 29.53  ? 255 PHE D C   1 
ATOM   11335 O O   . PHE D 1 255 ? 33.173  28.674  -6.478  1.00 29.38  ? 255 PHE D O   1 
ATOM   11336 C CB  . PHE D 1 255 ? 29.879  28.721  -6.666  1.00 28.30  ? 255 PHE D CB  1 
ATOM   11337 C CG  . PHE D 1 255 ? 30.209  27.454  -5.915  1.00 30.41  ? 255 PHE D CG  1 
ATOM   11338 C CD1 . PHE D 1 255 ? 30.091  26.215  -6.528  1.00 30.34  ? 255 PHE D CD1 1 
ATOM   11339 C CD2 . PHE D 1 255 ? 30.566  27.495  -4.577  1.00 26.69  ? 255 PHE D CD2 1 
ATOM   11340 C CE1 . PHE D 1 255 ? 30.360  25.039  -5.829  1.00 31.76  ? 255 PHE D CE1 1 
ATOM   11341 C CE2 . PHE D 1 255 ? 30.838  26.329  -3.871  1.00 28.25  ? 255 PHE D CE2 1 
ATOM   11342 C CZ  . PHE D 1 255 ? 30.739  25.098  -4.489  1.00 28.60  ? 255 PHE D CZ  1 
ATOM   11343 N N   . PHE D 1 256 ? 32.306  30.627  -5.731  1.00 26.73  ? 256 PHE D N   1 
ATOM   11344 C CA  . PHE D 1 256 ? 33.321  30.930  -4.737  1.00 21.70  ? 256 PHE D CA  1 
ATOM   11345 C C   . PHE D 1 256 ? 32.709  30.753  -3.363  1.00 24.39  ? 256 PHE D C   1 
ATOM   11346 O O   . PHE D 1 256 ? 31.539  31.080  -3.159  1.00 26.88  ? 256 PHE D O   1 
ATOM   11347 C CB  . PHE D 1 256 ? 33.817  32.371  -4.870  1.00 24.01  ? 256 PHE D CB  1 
ATOM   11348 C CG  . PHE D 1 256 ? 34.427  32.698  -6.202  1.00 23.67  ? 256 PHE D CG  1 
ATOM   11349 C CD1 . PHE D 1 256 ? 35.089  31.726  -6.941  1.00 29.12  ? 256 PHE D CD1 1 
ATOM   11350 C CD2 . PHE D 1 256 ? 34.370  33.984  -6.703  1.00 24.88  ? 256 PHE D CD2 1 
ATOM   11351 C CE1 . PHE D 1 256 ? 35.654  32.031  -8.162  1.00 25.48  ? 256 PHE D CE1 1 
ATOM   11352 C CE2 . PHE D 1 256 ? 34.941  34.301  -7.929  1.00 25.24  ? 256 PHE D CE2 1 
ATOM   11353 C CZ  . PHE D 1 256 ? 35.589  33.330  -8.650  1.00 25.85  ? 256 PHE D CZ  1 
ATOM   11354 N N   . GLU D 1 257 ? 33.485  30.250  -2.416  1.00 26.49  ? 257 GLU D N   1 
ATOM   11355 C CA  . GLU D 1 257 ? 32.985  30.006  -1.072  1.00 19.41  ? 257 GLU D CA  1 
ATOM   11356 C C   . GLU D 1 257 ? 33.860  30.758  -0.072  1.00 20.53  ? 257 GLU D C   1 
ATOM   11357 O O   . GLU D 1 257 ? 35.085  30.817  -0.229  1.00 21.56  ? 257 GLU D O   1 
ATOM   11358 C CB  . GLU D 1 257 ? 32.943  28.488  -0.782  1.00 21.64  ? 257 GLU D CB  1 
ATOM   11359 C CG  . GLU D 1 257 ? 32.430  28.083  0.610   1.00 19.77  ? 257 GLU D CG  1 
ATOM   11360 C CD  . GLU D 1 257 ? 31.689  26.761  0.630   1.00 23.41  ? 257 GLU D CD  1 
ATOM   11361 O OE1 . GLU D 1 257 ? 32.017  25.871  -0.180  1.00 20.91  ? 257 GLU D OE1 1 
ATOM   11362 O OE2 . GLU D 1 257 ? 30.758  26.611  1.455   1.00 22.74  ? 257 GLU D OE2 1 
ATOM   11363 N N   . TYR D 1 258 ? 33.226  31.344  0.949   1.00 19.98  ? 258 TYR D N   1 
ATOM   11364 C CA  . TYR D 1 258 ? 33.898  32.213  1.909   1.00 21.03  ? 258 TYR D CA  1 
ATOM   11365 C C   . TYR D 1 258 ? 33.503  31.877  3.335   1.00 19.20  ? 258 TYR D C   1 
ATOM   11366 O O   . TYR D 1 258 ? 32.392  31.420  3.595   1.00 17.96  ? 258 TYR D O   1 
ATOM   11367 C CB  . TYR D 1 258 ? 33.564  33.709  1.694   1.00 23.09  ? 258 TYR D CB  1 
ATOM   11368 C CG  . TYR D 1 258 ? 33.810  34.201  0.298   1.00 22.79  ? 258 TYR D CG  1 
ATOM   11369 C CD1 . TYR D 1 258 ? 32.888  33.955  -0.713  1.00 21.76  ? 258 TYR D CD1 1 
ATOM   11370 C CD2 . TYR D 1 258 ? 34.969  34.901  -0.015  1.00 19.89  ? 258 TYR D CD2 1 
ATOM   11371 C CE1 . TYR D 1 258 ? 33.110  34.392  -1.997  1.00 21.11  ? 258 TYR D CE1 1 
ATOM   11372 C CE2 . TYR D 1 258 ? 35.196  35.343  -1.297  1.00 22.80  ? 258 TYR D CE2 1 
ATOM   11373 C CZ  . TYR D 1 258 ? 34.260  35.081  -2.279  1.00 20.58  ? 258 TYR D CZ  1 
ATOM   11374 O OH  . TYR D 1 258 ? 34.477  35.505  -3.556  1.00 24.68  ? 258 TYR D OH  1 
ATOM   11375 N N   . HIS D 1 259 ? 34.409  32.170  4.266   1.00 24.80  ? 259 HIS D N   1 
ATOM   11376 C CA  . HIS D 1 259 ? 34.098  32.205  5.691   1.00 21.47  ? 259 HIS D CA  1 
ATOM   11377 C C   . HIS D 1 259 ? 34.154  33.659  6.161   1.00 24.10  ? 259 HIS D C   1 
ATOM   11378 O O   . HIS D 1 259 ? 35.135  34.366  5.900   1.00 23.91  ? 259 HIS D O   1 
ATOM   11379 C CB  . HIS D 1 259 ? 35.075  31.331  6.480   1.00 22.57  ? 259 HIS D CB  1 
ATOM   11380 C CG  . HIS D 1 259 ? 34.864  31.389  7.955   1.00 23.95  ? 259 HIS D CG  1 
ATOM   11381 N ND1 . HIS D 1 259 ? 35.615  32.198  8.781   1.00 23.30  ? 259 HIS D ND1 1 
ATOM   11382 C CD2 . HIS D 1 259 ? 33.965  30.764  8.751   1.00 21.45  ? 259 HIS D CD2 1 
ATOM   11383 C CE1 . HIS D 1 259 ? 35.187  32.069  10.024  1.00 26.36  ? 259 HIS D CE1 1 
ATOM   11384 N NE2 . HIS D 1 259 ? 34.186  31.205  10.033  1.00 24.98  ? 259 HIS D NE2 1 
ATOM   11385 N N   . LEU D 1 260 ? 33.087  34.118  6.806   1.00 23.95  ? 260 LEU D N   1 
ATOM   11386 C CA  . LEU D 1 260 ? 32.962  35.498  7.268   1.00 26.03  ? 260 LEU D CA  1 
ATOM   11387 C C   . LEU D 1 260 ? 32.934  35.474  8.791   1.00 20.63  ? 260 LEU D C   1 
ATOM   11388 O O   . LEU D 1 260 ? 32.175  34.689  9.365   1.00 23.06  ? 260 LEU D O   1 
ATOM   11389 C CB  . LEU D 1 260 ? 31.675  36.141  6.719   1.00 18.94  ? 260 LEU D CB  1 
ATOM   11390 C CG  . LEU D 1 260 ? 31.639  36.784  5.334   1.00 23.04  ? 260 LEU D CG  1 
ATOM   11391 C CD1 . LEU D 1 260 ? 32.176  35.883  4.253   1.00 22.64  ? 260 LEU D CD1 1 
ATOM   11392 C CD2 . LEU D 1 260 ? 30.232  37.203  4.978   1.00 21.14  ? 260 LEU D CD2 1 
ATOM   11393 N N   . ASP D 1 261 ? 33.740  36.330  9.456   1.00 22.33  ? 261 ASP D N   1 
ATOM   11394 C CA  . ASP D 1 261 ? 33.785  36.251  10.913  1.00 22.74  ? 261 ASP D CA  1 
ATOM   11395 C C   . ASP D 1 261 ? 33.900  37.541  11.710  1.00 34.47  ? 261 ASP D C   1 
ATOM   11396 O O   . ASP D 1 261 ? 33.988  37.452  12.939  1.00 45.19  ? 261 ASP D O   1 
ATOM   11397 C CB  . ASP D 1 261 ? 34.930  35.339  11.367  1.00 25.76  ? 261 ASP D CB  1 
ATOM   11398 C CG  . ASP D 1 261 ? 36.323  35.974  11.243  1.00 25.73  ? 261 ASP D CG  1 
ATOM   11399 O OD1 . ASP D 1 261 ? 36.505  37.154  10.898  1.00 27.74  ? 261 ASP D OD1 1 
ATOM   11400 O OD2 . ASP D 1 261 ? 37.286  35.243  11.513  1.00 28.95  ? 261 ASP D OD2 1 
ATOM   11401 N N   . GLY D 1 262 ? 33.947  38.715  11.116  1.00 29.45  ? 262 GLY D N   1 
ATOM   11402 C CA  . GLY D 1 262 ? 34.127  39.894  11.952  1.00 34.54  ? 262 GLY D CA  1 
ATOM   11403 C C   . GLY D 1 262 ? 35.536  40.464  11.968  1.00 31.01  ? 262 GLY D C   1 
ATOM   11404 O O   . GLY D 1 262 ? 35.707  41.624  12.352  1.00 31.08  ? 262 GLY D O   1 
ATOM   11405 N N   . ASP D 1 263 ? 36.541  39.673  11.573  1.00 25.38  ? 263 ASP D N   1 
ATOM   11406 C CA  . ASP D 1 263 ? 37.844  40.157  11.117  1.00 31.24  ? 263 ASP D CA  1 
ATOM   11407 C C   . ASP D 1 263 ? 37.900  40.320  9.606   1.00 29.35  ? 263 ASP D C   1 
ATOM   11408 O O   . ASP D 1 263 ? 38.533  41.252  9.103   1.00 26.00  ? 263 ASP D O   1 
ATOM   11409 C CB  . ASP D 1 263 ? 38.971  39.191  11.503  1.00 30.13  ? 263 ASP D CB  1 
ATOM   11410 C CG  . ASP D 1 263 ? 39.185  39.105  12.983  1.00 35.25  ? 263 ASP D CG  1 
ATOM   11411 O OD1 . ASP D 1 263 ? 39.166  40.168  13.637  1.00 31.31  ? 263 ASP D OD1 1 
ATOM   11412 O OD2 . ASP D 1 263 ? 39.403  37.973  13.484  1.00 38.25  ? 263 ASP D OD2 1 
ATOM   11413 N N   . ARG D 1 264 ? 37.259  39.417  8.872   1.00 28.58  ? 264 ARG D N   1 
ATOM   11414 C CA  . ARG D 1 264 ? 37.505  39.338  7.444   1.00 30.90  ? 264 ARG D CA  1 
ATOM   11415 C C   . ARG D 1 264 ? 36.472  38.424  6.818   1.00 27.21  ? 264 ARG D C   1 
ATOM   11416 O O   . ARG D 1 264 ? 35.798  37.642  7.498   1.00 23.04  ? 264 ARG D O   1 
ATOM   11417 C CB  . ARG D 1 264 ? 38.919  38.807  7.148   1.00 23.55  ? 264 ARG D CB  1 
ATOM   11418 C CG  . ARG D 1 264 ? 39.294  37.644  8.050   1.00 30.21  ? 264 ARG D CG  1 
ATOM   11419 C CD  . ARG D 1 264 ? 39.366  36.385  7.261   1.00 31.50  ? 264 ARG D CD  1 
ATOM   11420 N NE  . ARG D 1 264 ? 39.445  35.184  8.083   1.00 30.01  ? 264 ARG D NE  1 
ATOM   11421 C CZ  . ARG D 1 264 ? 38.397  34.431  8.387   1.00 30.06  ? 264 ARG D CZ  1 
ATOM   11422 N NH1 . ARG D 1 264 ? 37.153  34.868  8.209   1.00 28.03  ? 264 ARG D NH1 1 
ATOM   11423 N NH2 . ARG D 1 264 ? 38.595  33.209  8.863   1.00 26.31  ? 264 ARG D NH2 1 
ATOM   11424 N N   . ALA D 1 265 ? 36.366  38.535  5.508   1.00 25.30  ? 265 ALA D N   1 
ATOM   11425 C CA  . ALA D 1 265 ? 35.802  37.487  4.681   1.00 26.69  ? 265 ALA D CA  1 
ATOM   11426 C C   . ALA D 1 265 ? 36.978  36.736  4.082   1.00 23.03  ? 265 ALA D C   1 
ATOM   11427 O O   . ALA D 1 265 ? 37.789  37.329  3.378   1.00 24.23  ? 265 ALA D O   1 
ATOM   11428 C CB  . ALA D 1 265 ? 34.916  38.067  3.585   1.00 24.41  ? 265 ALA D CB  1 
ATOM   11429 N N   . ARG D 1 266 ? 37.083  35.455  4.377   1.00 25.44  ? 266 ARG D N   1 
ATOM   11430 C CA  . ARG D 1 266 ? 38.186  34.638  3.898   1.00 26.30  ? 266 ARG D CA  1 
ATOM   11431 C C   . ARG D 1 266 ? 37.718  33.853  2.688   1.00 23.54  ? 266 ARG D C   1 
ATOM   11432 O O   . ARG D 1 266 ? 36.784  33.060  2.803   1.00 20.35  ? 266 ARG D O   1 
ATOM   11433 C CB  . ARG D 1 266 ? 38.675  33.672  4.976   1.00 26.24  ? 266 ARG D CB  1 
ATOM   11434 C CG  . ARG D 1 266 ? 39.908  32.882  4.533   1.00 27.81  ? 266 ARG D CG  1 
ATOM   11435 C CD  . ARG D 1 266 ? 41.146  33.501  5.139   1.00 36.52  ? 266 ARG D CD  1 
ATOM   11436 N NE  . ARG D 1 266 ? 41.641  34.565  4.281   1.00 38.10  ? 266 ARG D NE  1 
ATOM   11437 C CZ  . ARG D 1 266 ? 42.285  35.641  4.715   1.00 39.18  ? 266 ARG D CZ  1 
ATOM   11438 N NH1 . ARG D 1 266 ? 42.608  35.789  5.995   1.00 35.41  ? 266 ARG D NH1 1 
ATOM   11439 N NH2 . ARG D 1 266 ? 42.595  36.599  3.847   1.00 37.42  ? 266 ARG D NH2 1 
ATOM   11440 N N   . PHE D 1 267 ? 38.359  34.081  1.534   1.00 23.86  ? 267 PHE D N   1 
ATOM   11441 C CA  . PHE D 1 267 ? 38.179  33.195  0.387   1.00 22.18  ? 267 PHE D CA  1 
ATOM   11442 C C   . PHE D 1 267 ? 38.712  31.798  0.711   1.00 24.46  ? 267 PHE D C   1 
ATOM   11443 O O   . PHE D 1 267 ? 39.863  31.643  1.131   1.00 26.26  ? 267 PHE D O   1 
ATOM   11444 C CB  . PHE D 1 267 ? 38.894  33.759  -0.839  1.00 26.19  ? 267 PHE D CB  1 
ATOM   11445 C CG  . PHE D 1 267 ? 38.707  32.929  -2.090  1.00 24.49  ? 267 PHE D CG  1 
ATOM   11446 C CD1 . PHE D 1 267 ? 37.629  33.158  -2.932  1.00 23.02  ? 267 PHE D CD1 1 
ATOM   11447 C CD2 . PHE D 1 267 ? 39.625  31.935  -2.431  1.00 26.31  ? 267 PHE D CD2 1 
ATOM   11448 C CE1 . PHE D 1 267 ? 37.456  32.404  -4.081  1.00 25.55  ? 267 PHE D CE1 1 
ATOM   11449 C CE2 . PHE D 1 267 ? 39.465  31.177  -3.582  1.00 26.96  ? 267 PHE D CE2 1 
ATOM   11450 C CZ  . PHE D 1 267 ? 38.382  31.409  -4.406  1.00 28.76  ? 267 PHE D CZ  1 
ATOM   11451 N N   . LEU D 1 268 ? 37.876  30.778  0.507   1.00 25.97  ? 268 LEU D N   1 
ATOM   11452 C CA  . LEU D 1 268 ? 38.218  29.389  0.808   1.00 21.46  ? 268 LEU D CA  1 
ATOM   11453 C C   . LEU D 1 268 ? 38.552  28.576  -0.438  1.00 25.59  ? 268 LEU D C   1 
ATOM   11454 O O   . LEU D 1 268 ? 39.600  27.931  -0.482  1.00 28.20  ? 268 LEU D O   1 
ATOM   11455 C CB  . LEU D 1 268 ? 37.065  28.719  1.561   1.00 21.85  ? 268 LEU D CB  1 
ATOM   11456 C CG  . LEU D 1 268 ? 36.701  29.282  2.942   1.00 23.88  ? 268 LEU D CG  1 
ATOM   11457 C CD1 . LEU D 1 268 ? 35.514  28.538  3.520   1.00 20.65  ? 268 LEU D CD1 1 
ATOM   11458 C CD2 . LEU D 1 268 ? 37.884  29.186  3.888   1.00 22.67  ? 268 LEU D CD2 1 
ATOM   11459 N N   . HIS D 1 269 ? 37.689  28.597  -1.457  1.00 21.14  ? 269 HIS D N   1 
ATOM   11460 C CA  . HIS D 1 269 ? 37.917  27.822  -2.672  1.00 26.61  ? 269 HIS D CA  1 
ATOM   11461 C C   . HIS D 1 269 ? 36.940  28.262  -3.755  1.00 27.81  ? 269 HIS D C   1 
ATOM   11462 O O   . HIS D 1 269 ? 35.840  28.753  -3.473  1.00 24.58  ? 269 HIS D O   1 
ATOM   11463 C CB  . HIS D 1 269 ? 37.757  26.310  -2.424  1.00 20.93  ? 269 HIS D CB  1 
ATOM   11464 C CG  . HIS D 1 269 ? 36.346  25.899  -2.155  1.00 21.78  ? 269 HIS D CG  1 
ATOM   11465 N ND1 . HIS D 1 269 ? 35.550  25.301  -3.109  1.00 22.38  ? 269 HIS D ND1 1 
ATOM   11466 C CD2 . HIS D 1 269 ? 35.575  26.029  -1.048  1.00 21.86  ? 269 HIS D CD2 1 
ATOM   11467 C CE1 . HIS D 1 269 ? 34.354  25.070  -2.599  1.00 21.47  ? 269 HIS D CE1 1 
ATOM   11468 N NE2 . HIS D 1 269 ? 34.340  25.508  -1.351  1.00 23.58  ? 269 HIS D NE2 1 
ATOM   11469 N N   . SER D 1 270 ? 37.353  28.045  -5.001  1.00 25.78  ? 270 SER D N   1 
ATOM   11470 C CA  . SER D 1 270 ? 36.474  28.056  -6.156  1.00 24.95  ? 270 SER D CA  1 
ATOM   11471 C C   . SER D 1 270 ? 36.238  26.612  -6.575  1.00 30.38  ? 270 SER D C   1 
ATOM   11472 O O   . SER D 1 270 ? 37.143  25.778  -6.451  1.00 26.82  ? 270 SER D O   1 
ATOM   11473 C CB  . SER D 1 270 ? 37.093  28.836  -7.310  1.00 25.95  ? 270 SER D CB  1 
ATOM   11474 O OG  . SER D 1 270 ? 38.163  28.110  -7.920  1.00 26.71  ? 270 SER D OG  1 
ATOM   11475 N N   . SER D 1 271 ? 35.024  26.321  -7.059  1.00 23.87  ? 271 SER D N   1 
ATOM   11476 C CA  . SER D 1 271 ? 34.642  24.989  -7.497  1.00 29.17  ? 271 SER D CA  1 
ATOM   11477 C C   . SER D 1 271 ? 33.685  25.094  -8.673  1.00 29.46  ? 271 SER D C   1 
ATOM   11478 O O   . SER D 1 271 ? 33.048  26.130  -8.885  1.00 36.75  ? 271 SER D O   1 
ATOM   11479 C CB  . SER D 1 271 ? 34.002  24.191  -6.360  1.00 31.04  ? 271 SER D CB  1 
ATOM   11480 O OG  . SER D 1 271 ? 35.004  23.785  -5.452  1.00 30.08  ? 271 SER D OG  1 
ATOM   11481 N N   . ILE D 1 272 ? 33.584  24.007  -9.440  1.00 32.20  ? 272 ILE D N   1 
ATOM   11482 C CA  . ILE D 1 272 ? 32.800  23.960  -10.674 1.00 35.09  ? 272 ILE D CA  1 
ATOM   11483 C C   . ILE D 1 272 ? 31.645  22.991  -10.494 1.00 35.45  ? 272 ILE D C   1 
ATOM   11484 O O   . ILE D 1 272 ? 31.862  21.832  -10.127 1.00 38.48  ? 272 ILE D O   1 
ATOM   11485 C CB  . ILE D 1 272 ? 33.653  23.523  -11.878 1.00 37.70  ? 272 ILE D CB  1 
ATOM   11486 C CG1 . ILE D 1 272 ? 34.781  24.501  -12.154 1.00 33.55  ? 272 ILE D CG1 1 
ATOM   11487 C CG2 . ILE D 1 272 ? 32.803  23.400  -13.138 1.00 35.35  ? 272 ILE D CG2 1 
ATOM   11488 C CD1 . ILE D 1 272 ? 35.471  24.223  -13.471 1.00 36.65  ? 272 ILE D CD1 1 
ATOM   11489 N N   . LEU D 1 273 ? 30.433  23.442  -10.807 1.00 38.04  ? 273 LEU D N   1 
ATOM   11490 C CA  . LEU D 1 273 ? 29.270  22.559  -10.825 1.00 40.45  ? 273 LEU D CA  1 
ATOM   11491 C C   . LEU D 1 273 ? 29.222  21.805  -12.146 1.00 39.60  ? 273 LEU D C   1 
ATOM   11492 O O   . LEU D 1 273 ? 29.300  22.407  -13.222 1.00 38.46  ? 273 LEU D O   1 
ATOM   11493 C CB  . LEU D 1 273 ? 27.974  23.343  -10.645 1.00 41.94  ? 273 LEU D CB  1 
ATOM   11494 C CG  . LEU D 1 273 ? 27.947  24.434  -9.580  1.00 47.47  ? 273 LEU D CG  1 
ATOM   11495 C CD1 . LEU D 1 273 ? 28.039  25.802  -10.267 1.00 48.41  ? 273 LEU D CD1 1 
ATOM   11496 C CD2 . LEU D 1 273 ? 26.709  24.318  -8.694  1.00 42.47  ? 273 LEU D CD2 1 
ATOM   11497 N N   . LYS D 1 274 ? 29.092  20.492  -12.063 1.00 41.44  ? 274 LYS D N   1 
ATOM   11498 C CA  . LYS D 1 274 ? 29.040  19.637  -13.235 1.00 40.27  ? 274 LYS D CA  1 
ATOM   11499 C C   . LYS D 1 274 ? 27.612  19.161  -13.431 1.00 45.07  ? 274 LYS D C   1 
ATOM   11500 O O   . LYS D 1 274 ? 26.962  18.723  -12.473 1.00 47.52  ? 274 LYS D O   1 
ATOM   11501 C CB  . LYS D 1 274 ? 29.977  18.437  -13.090 1.00 45.15  ? 274 LYS D CB  1 
ATOM   11502 C CG  . LYS D 1 274 ? 31.470  18.780  -13.021 1.00 46.41  ? 274 LYS D CG  1 
ATOM   11503 C CD  . LYS D 1 274 ? 31.822  20.086  -13.724 1.00 44.20  ? 274 LYS D CD  1 
ATOM   11504 C CE  . LYS D 1 274 ? 32.396  19.872  -15.121 1.00 47.95  ? 274 LYS D CE  1 
ATOM   11505 N NZ  . LYS D 1 274 ? 32.579  21.197  -15.823 1.00 51.02  ? 274 LYS D NZ  1 
ATOM   11506 N N   . TYR D 1 275 ? 27.130  19.244  -14.668 1.00 45.18  ? 275 TYR D N   1 
ATOM   11507 C CA  . TYR D 1 275 ? 25.820  18.738  -15.036 1.00 50.98  ? 275 TYR D CA  1 
ATOM   11508 C C   . TYR D 1 275 ? 25.964  17.630  -16.076 1.00 53.44  ? 275 TYR D C   1 
ATOM   11509 O O   . TYR D 1 275 ? 27.002  17.487  -16.727 1.00 52.73  ? 275 TYR D O   1 
ATOM   11510 C CB  . TYR D 1 275 ? 24.926  19.875  -15.545 1.00 48.70  ? 275 TYR D CB  1 
ATOM   11511 C CG  . TYR D 1 275 ? 24.751  20.985  -14.527 1.00 49.38  ? 275 TYR D CG  1 
ATOM   11512 C CD1 . TYR D 1 275 ? 25.705  21.984  -14.379 1.00 50.57  ? 275 TYR D CD1 1 
ATOM   11513 C CD2 . TYR D 1 275 ? 23.640  21.019  -13.693 1.00 52.19  ? 275 TYR D CD2 1 
ATOM   11514 C CE1 . TYR D 1 275 ? 25.551  22.995  -13.440 1.00 48.65  ? 275 TYR D CE1 1 
ATOM   11515 C CE2 . TYR D 1 275 ? 23.479  22.028  -12.751 1.00 48.25  ? 275 TYR D CE2 1 
ATOM   11516 C CZ  . TYR D 1 275 ? 24.435  23.011  -12.632 1.00 48.46  ? 275 TYR D CZ  1 
ATOM   11517 O OH  . TYR D 1 275 ? 24.279  24.015  -11.697 1.00 52.78  ? 275 TYR D OH  1 
ATOM   11518 N N   . GLU D 1 276 ? 24.915  16.825  -16.205 1.00 56.44  ? 276 GLU D N   1 
ATOM   11519 C CA  . GLU D 1 276 ? 24.950  15.689  -17.116 1.00 62.01  ? 276 GLU D CA  1 
ATOM   11520 C C   . GLU D 1 276 ? 25.000  16.156  -18.570 1.00 61.43  ? 276 GLU D C   1 
ATOM   11521 O O   . GLU D 1 276 ? 24.536  17.250  -18.911 1.00 60.52  ? 276 GLU D O   1 
ATOM   11522 C CB  . GLU D 1 276 ? 23.729  14.789  -16.887 1.00 59.37  ? 276 GLU D CB  1 
ATOM   11523 C CG  . GLU D 1 276 ? 23.690  13.531  -17.762 1.00 65.91  ? 276 GLU D CG  1 
ATOM   11524 C CD  . GLU D 1 276 ? 22.328  13.292  -18.408 1.00 67.04  ? 276 GLU D CD  1 
ATOM   11525 O OE1 . GLU D 1 276 ? 21.344  13.932  -17.968 1.00 62.68  ? 276 GLU D OE1 1 
ATOM   11526 O OE2 . GLU D 1 276 ? 22.249  12.482  -19.365 1.00 59.75  ? 276 GLU D OE2 1 
ATOM   11527 N N   . GLN D 1 277 ? 25.592  15.323  -19.426 1.00 60.65  ? 277 GLN D N   1 
ATOM   11528 C CA  . GLN D 1 277 ? 25.542  15.539  -20.875 1.00 66.42  ? 277 GLN D CA  1 
ATOM   11529 C C   . GLN D 1 277 ? 24.525  14.599  -21.521 1.00 59.47  ? 277 GLN D C   1 
ATOM   11530 O O   . GLN D 1 277 ? 23.946  14.916  -22.560 1.00 65.14  ? 277 GLN D O   1 
ATOM   11531 C CB  . GLN D 1 277 ? 26.929  15.332  -21.507 1.00 71.02  ? 277 GLN D CB  1 
ATOM   11532 C CG  . GLN D 1 277 ? 28.090  15.903  -20.690 1.00 65.81  ? 277 GLN D CG  1 
ATOM   11533 C CD  . GLN D 1 277 ? 28.086  17.428  -20.610 1.00 68.55  ? 277 GLN D CD  1 
ATOM   11534 O OE1 . GLN D 1 277 ? 27.217  18.094  -21.170 1.00 71.84  ? 277 GLN D OE1 1 
ATOM   11535 N NE2 . GLN D 1 277 ? 29.072  17.984  -19.915 1.00 71.54  ? 277 GLN D NE2 1 
ATOM   11536 N N   . GLY D 1 283 ? 12.258  13.993  -14.675 1.00 74.58  ? 283 GLY D N   1 
ATOM   11537 C CA  . GLY D 1 283 ? 12.558  15.408  -14.558 1.00 72.11  ? 283 GLY D CA  1 
ATOM   11538 C C   . GLY D 1 283 ? 13.959  15.662  -14.043 1.00 75.47  ? 283 GLY D C   1 
ATOM   11539 O O   . GLY D 1 283 ? 14.301  15.244  -12.935 1.00 81.09  ? 283 GLY D O   1 
ATOM   11540 N N   . GLY D 1 284 ? 14.770  16.344  -14.852 1.00 72.17  ? 284 GLY D N   1 
ATOM   11541 C CA  . GLY D 1 284 ? 16.149  16.647  -14.505 1.00 74.30  ? 284 GLY D CA  1 
ATOM   11542 C C   . GLY D 1 284 ? 16.722  17.788  -15.324 1.00 68.94  ? 284 GLY D C   1 
ATOM   11543 O O   . GLY D 1 284 ? 17.294  18.734  -14.767 1.00 65.67  ? 284 GLY D O   1 
ATOM   11544 N N   . SER D 1 285 ? 16.586  17.689  -16.654 1.00 70.27  ? 285 SER D N   1 
ATOM   11545 C CA  . SER D 1 285 ? 16.862  18.789  -17.585 1.00 63.65  ? 285 SER D CA  1 
ATOM   11546 C C   . SER D 1 285 ? 18.312  19.259  -17.503 1.00 62.09  ? 285 SER D C   1 
ATOM   11547 O O   . SER D 1 285 ? 18.589  20.458  -17.438 1.00 62.50  ? 285 SER D O   1 
ATOM   11548 C CB  . SER D 1 285 ? 15.909  19.959  -17.343 1.00 52.77  ? 285 SER D CB  1 
ATOM   11549 O OG  . SER D 1 285 ? 16.121  20.946  -18.328 1.00 55.98  ? 285 SER D OG  1 
ATOM   11550 N N   . ALA D 1 286 ? 19.235  18.294  -17.560 1.00 62.79  ? 286 ALA D N   1 
ATOM   11551 C CA  . ALA D 1 286 ? 20.626  18.438  -17.136 1.00 56.54  ? 286 ALA D CA  1 
ATOM   11552 C C   . ALA D 1 286 ? 20.682  18.592  -15.621 1.00 57.70  ? 286 ALA D C   1 
ATOM   11553 O O   . ALA D 1 286 ? 20.645  19.708  -15.087 1.00 55.54  ? 286 ALA D O   1 
ATOM   11554 C CB  . ALA D 1 286 ? 21.326  19.606  -17.834 1.00 57.32  ? 286 ALA D CB  1 
ATOM   11555 N N   . LYS D 1 287 ? 20.772  17.465  -14.925 1.00 57.77  ? 287 LYS D N   1 
ATOM   11556 C CA  . LYS D 1 287 ? 20.802  17.451  -13.473 1.00 59.84  ? 287 LYS D CA  1 
ATOM   11557 C C   . LYS D 1 287 ? 22.233  17.589  -12.939 1.00 55.35  ? 287 LYS D C   1 
ATOM   11558 O O   . LYS D 1 287 ? 23.220  17.559  -13.678 1.00 46.64  ? 287 LYS D O   1 
ATOM   11559 C CB  . LYS D 1 287 ? 20.143  16.172  -12.951 1.00 58.54  ? 287 LYS D CB  1 
ATOM   11560 C CG  . LYS D 1 287 ? 20.950  14.907  -13.191 1.00 56.25  ? 287 LYS D CG  1 
ATOM   11561 C CD  . LYS D 1 287 ? 20.643  13.860  -12.132 1.00 55.45  ? 287 LYS D CD  1 
ATOM   11562 C CE  . LYS D 1 287 ? 19.235  13.302  -12.284 1.00 59.42  ? 287 LYS D CE  1 
ATOM   11563 N NZ  . LYS D 1 287 ? 19.158  12.212  -13.305 1.00 62.03  ? 287 LYS D NZ  1 
ATOM   11564 N N   . TRP D 1 288 ? 22.324  17.754  -11.622 1.00 51.37  ? 288 TRP D N   1 
ATOM   11565 C CA  . TRP D 1 288 ? 23.599  17.902  -10.939 1.00 48.17  ? 288 TRP D CA  1 
ATOM   11566 C C   . TRP D 1 288 ? 24.218  16.533  -10.679 1.00 49.78  ? 288 TRP D C   1 
ATOM   11567 O O   . TRP D 1 288 ? 23.553  15.632  -10.160 1.00 48.48  ? 288 TRP D O   1 
ATOM   11568 C CB  . TRP D 1 288 ? 23.390  18.653  -9.630  1.00 50.58  ? 288 TRP D CB  1 
ATOM   11569 C CG  . TRP D 1 288 ? 24.619  18.842  -8.807  1.00 49.55  ? 288 TRP D CG  1 
ATOM   11570 C CD1 . TRP D 1 288 ? 25.809  19.371  -9.214  1.00 45.51  ? 288 TRP D CD1 1 
ATOM   11571 C CD2 . TRP D 1 288 ? 24.768  18.535  -7.416  1.00 44.74  ? 288 TRP D CD2 1 
ATOM   11572 N NE1 . TRP D 1 288 ? 26.696  19.400  -8.161  1.00 48.62  ? 288 TRP D NE1 1 
ATOM   11573 C CE2 . TRP D 1 288 ? 26.079  18.890  -7.048  1.00 46.16  ? 288 TRP D CE2 1 
ATOM   11574 C CE3 . TRP D 1 288 ? 23.917  17.997  -6.449  1.00 42.94  ? 288 TRP D CE3 1 
ATOM   11575 C CZ2 . TRP D 1 288 ? 26.559  18.723  -5.756  1.00 42.43  ? 288 TRP D CZ2 1 
ATOM   11576 C CZ3 . TRP D 1 288 ? 24.397  17.831  -5.169  1.00 45.03  ? 288 TRP D CZ3 1 
ATOM   11577 C CH2 . TRP D 1 288 ? 25.703  18.196  -4.834  1.00 39.92  ? 288 TRP D CH2 1 
ATOM   11578 N N   . ILE D 1 289 ? 25.487  16.376  -11.050 1.00 45.93  ? 289 ILE D N   1 
ATOM   11579 C CA  . ILE D 1 289 ? 26.160  15.087  -10.947 1.00 47.26  ? 289 ILE D CA  1 
ATOM   11580 C C   . ILE D 1 289 ? 27.377  15.120  -10.030 1.00 47.50  ? 289 ILE D C   1 
ATOM   11581 O O   . ILE D 1 289 ? 27.876  14.047  -9.649  1.00 48.42  ? 289 ILE D O   1 
ATOM   11582 C CB  . ILE D 1 289 ? 26.559  14.567  -12.343 1.00 47.14  ? 289 ILE D CB  1 
ATOM   11583 C CG1 . ILE D 1 289 ? 27.608  15.497  -12.959 1.00 50.06  ? 289 ILE D CG1 1 
ATOM   11584 C CG2 . ILE D 1 289 ? 25.330  14.481  -13.244 1.00 51.34  ? 289 ILE D CG2 1 
ATOM   11585 C CD1 . ILE D 1 289 ? 27.769  15.361  -14.456 1.00 50.41  ? 289 ILE D CD1 1 
ATOM   11586 N N   . GLY D 1 290 ? 27.867  16.293  -9.650  1.00 45.97  ? 290 GLY D N   1 
ATOM   11587 C CA  . GLY D 1 290 ? 28.996  16.404  -8.750  1.00 41.50  ? 290 GLY D CA  1 
ATOM   11588 C C   . GLY D 1 290 ? 29.638  17.767  -8.918  1.00 41.94  ? 290 GLY D C   1 
ATOM   11589 O O   . GLY D 1 290 ? 29.049  18.672  -9.504  1.00 41.07  ? 290 GLY D O   1 
ATOM   11590 N N   . LEU D 1 291 ? 30.860  17.894  -8.407  1.00 37.94  ? 291 LEU D N   1 
ATOM   11591 C CA  . LEU D 1 291 ? 31.574  19.131  -8.671  1.00 38.10  ? 291 LEU D CA  1 
ATOM   11592 C C   . LEU D 1 291 ? 33.075  18.889  -8.786  1.00 38.16  ? 291 LEU D C   1 
ATOM   11593 O O   . LEU D 1 291 ? 33.615  17.912  -8.249  1.00 35.31  ? 291 LEU D O   1 
ATOM   11594 C CB  . LEU D 1 291 ? 31.232  20.200  -7.617  1.00 37.96  ? 291 LEU D CB  1 
ATOM   11595 C CG  . LEU D 1 291 ? 31.524  20.130  -6.137  1.00 35.49  ? 291 LEU D CG  1 
ATOM   11596 C CD1 . LEU D 1 291 ? 32.998  20.335  -5.901  1.00 40.07  ? 291 LEU D CD1 1 
ATOM   11597 C CD2 . LEU D 1 291 ? 30.713  21.209  -5.403  1.00 32.15  ? 291 LEU D CD2 1 
ATOM   11598 N N   . ASP D 1 292 ? 33.726  19.786  -9.531  1.00 35.13  ? 292 ASP D N   1 
ATOM   11599 C CA  . ASP D 1 292 ? 35.166  19.821  -9.714  1.00 35.31  ? 292 ASP D CA  1 
ATOM   11600 C C   . ASP D 1 292 ? 35.739  21.020  -8.971  1.00 38.16  ? 292 ASP D C   1 
ATOM   11601 O O   . ASP D 1 292 ? 35.079  22.055  -8.823  1.00 32.10  ? 292 ASP D O   1 
ATOM   11602 C CB  . ASP D 1 292 ? 35.557  19.923  -11.201 1.00 38.12  ? 292 ASP D CB  1 
ATOM   11603 C CG  . ASP D 1 292 ? 35.140  18.704  -12.014 1.00 39.75  ? 292 ASP D CG  1 
ATOM   11604 O OD1 . ASP D 1 292 ? 34.643  17.714  -11.427 1.00 38.39  ? 292 ASP D OD1 1 
ATOM   11605 O OD2 . ASP D 1 292 ? 35.318  18.739  -13.249 1.00 38.29  ? 292 ASP D OD2 1 
ATOM   11606 N N   . SER D 1 293 ? 36.982  20.879  -8.516  1.00 30.78  ? 293 SER D N   1 
ATOM   11607 C CA  . SER D 1 293 ? 37.572  22.011  -7.823  1.00 36.94  ? 293 SER D CA  1 
ATOM   11608 C C   . SER D 1 293 ? 39.014  22.189  -8.246  1.00 34.83  ? 293 SER D C   1 
ATOM   11609 O O   . SER D 1 293 ? 39.576  21.301  -8.898  1.00 38.61  ? 293 SER D O   1 
ATOM   11610 C CB  . SER D 1 293 ? 37.472  21.883  -6.308  1.00 34.51  ? 293 SER D CB  1 
ATOM   11611 O OG  . SER D 1 293 ? 37.670  23.167  -5.743  1.00 34.94  ? 293 SER D OG  1 
ATOM   11612 N N   . PRO D 1 294 ? 39.684  23.181  -7.724  1.00 40.36  ? 294 PRO D N   1 
ATOM   11613 C CA  . PRO D 1 294 ? 40.170  24.253  -8.588  1.00 34.39  ? 294 PRO D CA  1 
ATOM   11614 C C   . PRO D 1 294 ? 39.259  24.530  -9.785  1.00 37.00  ? 294 PRO D C   1 
ATOM   11615 O O   . PRO D 1 294 ? 39.402  23.903  -10.834 1.00 37.25  ? 294 PRO D O   1 
ATOM   11616 C CB  . PRO D 1 294 ? 41.559  23.753  -9.003  1.00 37.48  ? 294 PRO D CB  1 
ATOM   11617 C CG  . PRO D 1 294 ? 42.002  23.037  -7.837  1.00 39.51  ? 294 PRO D CG  1 
ATOM   11618 C CD  . PRO D 1 294 ? 40.809  22.425  -7.162  1.00 40.72  ? 294 PRO D CD  1 
ATOM   11619 N N   . SER D 1 295 ? 38.322  25.470  -9.646  1.00 38.07  ? 295 SER D N   1 
ATOM   11620 C CA  . SER D 1 295 ? 37.653  26.029  -10.817 1.00 32.41  ? 295 SER D CA  1 
ATOM   11621 C C   . SER D 1 295 ? 38.683  26.707  -11.713 1.00 31.14  ? 295 SER D C   1 
ATOM   11622 O O   . SER D 1 295 ? 39.823  26.934  -11.319 1.00 34.16  ? 295 SER D O   1 
ATOM   11623 C CB  . SER D 1 295 ? 36.586  27.042  -10.410 1.00 32.30  ? 295 SER D CB  1 
ATOM   11624 O OG  . SER D 1 295 ? 37.104  28.365  -10.411 1.00 31.17  ? 295 SER D OG  1 
ATOM   11625 N N   . ARG D 1 296 ? 38.272  27.051  -12.930 1.00 25.57  ? 296 ARG D N   1 
ATOM   11626 C CA  . ARG D 1 296 ? 39.173  27.741  -13.849 1.00 36.04  ? 296 ARG D CA  1 
ATOM   11627 C C   . ARG D 1 296 ? 38.850  29.225  -13.975 1.00 31.90  ? 296 ARG D C   1 
ATOM   11628 O O   . ARG D 1 296 ? 39.327  29.876  -14.906 1.00 30.80  ? 296 ARG D O   1 
ATOM   11629 C CB  . ARG D 1 296 ? 39.157  27.071  -15.230 1.00 35.76  ? 296 ARG D CB  1 
ATOM   11630 C CG  . ARG D 1 296 ? 40.260  26.017  -15.411 1.00 45.75  ? 296 ARG D CG  1 
ATOM   11631 C CD  . ARG D 1 296 ? 41.484  26.581  -16.180 1.00 52.67  ? 296 ARG D CD  1 
ATOM   11632 N NE  . ARG D 1 296 ? 42.311  27.516  -15.410 1.00 50.63  ? 296 ARG D NE  1 
ATOM   11633 C CZ  . ARG D 1 296 ? 43.190  27.172  -14.473 1.00 51.22  ? 296 ARG D CZ  1 
ATOM   11634 N NH1 . ARG D 1 296 ? 43.377  25.908  -14.125 1.00 59.54  ? 296 ARG D NH1 1 
ATOM   11635 N NH2 . ARG D 1 296 ? 43.904  28.121  -13.873 1.00 53.49  ? 296 ARG D NH2 1 
ATOM   11636 N N   . SER D 1 297 ? 38.101  29.784  -13.023 1.00 31.28  ? 297 SER D N   1 
ATOM   11637 C CA  . SER D 1 297 ? 37.528  31.117  -13.158 1.00 34.19  ? 297 SER D CA  1 
ATOM   11638 C C   . SER D 1 297 ? 38.049  32.104  -12.113 1.00 30.12  ? 297 SER D C   1 
ATOM   11639 O O   . SER D 1 297 ? 37.382  33.090  -11.807 1.00 31.83  ? 297 SER D O   1 
ATOM   11640 C CB  . SER D 1 297 ? 36.003  31.036  -13.088 1.00 31.05  ? 297 SER D CB  1 
ATOM   11641 O OG  . SER D 1 297 ? 35.446  30.591  -14.310 1.00 32.29  ? 297 SER D OG  1 
ATOM   11642 N N   . GLU D 1 298 ? 39.236  31.867  -11.561 1.00 32.04  ? 298 GLU D N   1 
ATOM   11643 C CA  . GLU D 1 298 ? 39.775  32.716  -10.495 1.00 33.37  ? 298 GLU D CA  1 
ATOM   11644 C C   . GLU D 1 298 ? 40.698  33.765  -11.112 1.00 35.89  ? 298 GLU D C   1 
ATOM   11645 O O   . GLU D 1 298 ? 41.922  33.638  -11.100 1.00 39.67  ? 298 GLU D O   1 
ATOM   11646 C CB  . GLU D 1 298 ? 40.515  31.877  -9.455  1.00 31.89  ? 298 GLU D CB  1 
ATOM   11647 C CG  . GLU D 1 298 ? 39.652  30.955  -8.581  1.00 34.33  ? 298 GLU D CG  1 
ATOM   11648 C CD  . GLU D 1 298 ? 40.485  30.272  -7.486  1.00 30.91  ? 298 GLU D CD  1 
ATOM   11649 O OE1 . GLU D 1 298 ? 41.599  30.775  -7.220  1.00 38.52  ? 298 GLU D OE1 1 
ATOM   11650 O OE2 . GLU D 1 298 ? 40.041  29.247  -6.902  1.00 26.10  ? 298 GLU D OE2 1 
ATOM   11651 N N   . PHE D 1 299 ? 40.096  34.827  -11.650 1.00 36.78  ? 299 PHE D N   1 
ATOM   11652 C CA  . PHE D 1 299 ? 40.851  35.969  -12.153 1.00 36.86  ? 299 PHE D CA  1 
ATOM   11653 C C   . PHE D 1 299 ? 40.172  37.256  -11.691 1.00 39.09  ? 299 PHE D C   1 
ATOM   11654 O O   . PHE D 1 299 ? 39.112  37.224  -11.053 1.00 36.50  ? 299 PHE D O   1 
ATOM   11655 C CB  . PHE D 1 299 ? 40.997  35.912  -13.677 1.00 38.89  ? 299 PHE D CB  1 
ATOM   11656 C CG  . PHE D 1 299 ? 39.757  35.504  -14.398 1.00 37.06  ? 299 PHE D CG  1 
ATOM   11657 C CD1 . PHE D 1 299 ? 38.779  36.433  -14.706 1.00 38.91  ? 299 PHE D CD1 1 
ATOM   11658 C CD2 . PHE D 1 299 ? 39.583  34.193  -14.798 1.00 38.56  ? 299 PHE D CD2 1 
ATOM   11659 C CE1 . PHE D 1 299 ? 37.634  36.059  -15.391 1.00 38.17  ? 299 PHE D CE1 1 
ATOM   11660 C CE2 . PHE D 1 299 ? 38.450  33.809  -15.491 1.00 41.26  ? 299 PHE D CE2 1 
ATOM   11661 C CZ  . PHE D 1 299 ? 37.469  34.751  -15.786 1.00 43.97  ? 299 PHE D CZ  1 
ATOM   11662 N N   . GLU D 1 300 ? 40.789  38.402  -12.022 1.00 38.35  ? 300 GLU D N   1 
ATOM   11663 C CA  . GLU D 1 300 ? 40.395  39.664  -11.393 1.00 40.25  ? 300 GLU D CA  1 
ATOM   11664 C C   . GLU D 1 300 ? 38.929  39.988  -11.636 1.00 39.54  ? 300 GLU D C   1 
ATOM   11665 O O   . GLU D 1 300 ? 38.214  40.379  -10.703 1.00 35.68  ? 300 GLU D O   1 
ATOM   11666 C CB  . GLU D 1 300 ? 41.269  40.818  -11.881 1.00 40.18  ? 300 GLU D CB  1 
ATOM   11667 C CG  . GLU D 1 300 ? 42.352  41.194  -10.899 1.00 49.53  ? 300 GLU D CG  1 
ATOM   11668 C CD  . GLU D 1 300 ? 43.193  39.999  -10.485 1.00 55.23  ? 300 GLU D CD  1 
ATOM   11669 O OE1 . GLU D 1 300 ? 43.739  39.319  -11.383 1.00 55.54  ? 300 GLU D OE1 1 
ATOM   11670 O OE2 . GLU D 1 300 ? 43.301  39.734  -9.267  1.00 59.82  ? 300 GLU D OE2 1 
ATOM   11671 N N   . ALA D 1 301 ? 38.455  39.819  -12.872 1.00 28.91  ? 301 ALA D N   1 
ATOM   11672 C CA  . ALA D 1 301 ? 37.101  40.255  -13.188 1.00 34.93  ? 301 ALA D CA  1 
ATOM   11673 C C   . ALA D 1 301 ? 36.030  39.393  -12.530 1.00 37.36  ? 301 ALA D C   1 
ATOM   11674 O O   . ALA D 1 301 ? 34.843  39.697  -12.677 1.00 36.81  ? 301 ALA D O   1 
ATOM   11675 C CB  . ALA D 1 301 ? 36.891  40.276  -14.708 1.00 33.79  ? 301 ALA D CB  1 
ATOM   11676 N N   . THR D 1 302 ? 36.399  38.306  -11.855 1.00 34.93  ? 302 THR D N   1 
ATOM   11677 C CA  . THR D 1 302 ? 35.438  37.555  -11.055 1.00 32.66  ? 302 THR D CA  1 
ATOM   11678 C C   . THR D 1 302 ? 35.662  37.713  -9.558  1.00 29.30  ? 302 THR D C   1 
ATOM   11679 O O   . THR D 1 302 ? 34.700  37.907  -8.816  1.00 29.14  ? 302 THR D O   1 
ATOM   11680 C CB  . THR D 1 302 ? 35.481  36.063  -11.423 1.00 31.65  ? 302 THR D CB  1 
ATOM   11681 O OG1 . THR D 1 302 ? 36.842  35.637  -11.557 1.00 34.09  ? 302 THR D OG1 1 
ATOM   11682 C CG2 . THR D 1 302 ? 34.747  35.812  -12.741 1.00 32.42  ? 302 THR D CG2 1 
ATOM   11683 N N   . LEU D 1 303 ? 36.922  37.674  -9.121  1.00 30.67  ? 303 LEU D N   1 
ATOM   11684 C CA  . LEU D 1 303 ? 37.266  37.705  -7.703  1.00 28.56  ? 303 LEU D CA  1 
ATOM   11685 C C   . LEU D 1 303 ? 36.929  39.046  -7.071  1.00 26.43  ? 303 LEU D C   1 
ATOM   11686 O O   . LEU D 1 303 ? 36.505  39.108  -5.908  1.00 22.79  ? 303 LEU D O   1 
ATOM   11687 C CB  . LEU D 1 303 ? 38.764  37.433  -7.538  1.00 30.19  ? 303 LEU D CB  1 
ATOM   11688 C CG  . LEU D 1 303 ? 39.302  36.093  -7.042  1.00 37.33  ? 303 LEU D CG  1 
ATOM   11689 C CD1 . LEU D 1 303 ? 38.243  35.037  -7.073  1.00 30.93  ? 303 LEU D CD1 1 
ATOM   11690 C CD2 . LEU D 1 303 ? 40.511  35.677  -7.889  1.00 30.73  ? 303 LEU D CD2 1 
ATOM   11691 N N   . LYS D 1 304 ? 37.166  40.126  -7.796  1.00 29.55  ? 304 LYS D N   1 
ATOM   11692 C CA  . LYS D 1 304 ? 37.089  41.447  -7.202  1.00 28.68  ? 304 LYS D CA  1 
ATOM   11693 C C   . LYS D 1 304 ? 35.627  41.877  -7.027  1.00 26.28  ? 304 LYS D C   1 
ATOM   11694 O O   . LYS D 1 304 ? 35.253  42.311  -5.931  1.00 24.47  ? 304 LYS D O   1 
ATOM   11695 C CB  . LYS D 1 304 ? 37.900  42.454  -8.024  1.00 26.26  ? 304 LYS D CB  1 
ATOM   11696 C CG  . LYS D 1 304 ? 38.522  43.507  -7.129  1.00 35.54  ? 304 LYS D CG  1 
ATOM   11697 C CD  . LYS D 1 304 ? 39.511  42.857  -6.155  1.00 37.69  ? 304 LYS D CD  1 
ATOM   11698 C CE  . LYS D 1 304 ? 40.835  42.510  -6.829  1.00 42.37  ? 304 LYS D CE  1 
ATOM   11699 N NZ  . LYS D 1 304 ? 41.422  41.241  -6.275  1.00 47.26  ? 304 LYS D NZ  1 
ATOM   11700 N N   . PRO D 1 305 ? 34.761  41.764  -8.039  1.00 26.91  ? 305 PRO D N   1 
ATOM   11701 C CA  . PRO D 1 305 ? 33.330  41.983  -7.755  1.00 20.81  ? 305 PRO D CA  1 
ATOM   11702 C C   . PRO D 1 305 ? 32.785  41.040  -6.690  1.00 24.76  ? 305 PRO D C   1 
ATOM   11703 O O   . PRO D 1 305 ? 32.090  41.506  -5.777  1.00 21.60  ? 305 PRO D O   1 
ATOM   11704 C CB  . PRO D 1 305 ? 32.654  41.777  -9.120  1.00 25.27  ? 305 PRO D CB  1 
ATOM   11705 C CG  . PRO D 1 305 ? 33.722  41.999  -10.130 1.00 28.81  ? 305 PRO D CG  1 
ATOM   11706 C CD  . PRO D 1 305 ? 35.029  41.622  -9.486  1.00 29.59  ? 305 PRO D CD  1 
ATOM   11707 N N   . ALA D 1 306 ? 33.112  39.740  -6.745  1.00 21.29  ? 306 ALA D N   1 
ATOM   11708 C CA  . ALA D 1 306 ? 32.691  38.830  -5.679  1.00 23.83  ? 306 ALA D CA  1 
ATOM   11709 C C   . ALA D 1 306 ? 33.151  39.326  -4.308  1.00 24.08  ? 306 ALA D C   1 
ATOM   11710 O O   . ALA D 1 306 ? 32.340  39.449  -3.382  1.00 20.76  ? 306 ALA D O   1 
ATOM   11711 C CB  . ALA D 1 306 ? 33.221  37.415  -5.931  1.00 21.96  ? 306 ALA D CB  1 
ATOM   11712 N N   . GLU D 1 307 ? 34.456  39.591  -4.161  1.00 20.54  ? 307 GLU D N   1 
ATOM   11713 C CA  . GLU D 1 307 ? 34.999  40.096  -2.902  1.00 26.38  ? 307 GLU D CA  1 
ATOM   11714 C C   . GLU D 1 307 ? 34.220  41.306  -2.401  1.00 26.06  ? 307 GLU D C   1 
ATOM   11715 O O   . GLU D 1 307 ? 33.937  41.422  -1.205  1.00 24.89  ? 307 GLU D O   1 
ATOM   11716 C CB  . GLU D 1 307 ? 36.481  40.472  -3.064  1.00 20.81  ? 307 GLU D CB  1 
ATOM   11717 C CG  . GLU D 1 307 ? 37.132  40.878  -1.752  1.00 27.44  ? 307 GLU D CG  1 
ATOM   11718 C CD  . GLU D 1 307 ? 38.388  41.758  -1.895  1.00 34.15  ? 307 GLU D CD  1 
ATOM   11719 O OE1 . GLU D 1 307 ? 38.974  41.830  -2.995  1.00 33.19  ? 307 GLU D OE1 1 
ATOM   11720 O OE2 . GLU D 1 307 ? 38.786  42.387  -0.887  1.00 31.36  ? 307 GLU D OE2 1 
ATOM   11721 N N   . GLU D 1 308 ? 33.876  42.225  -3.308  1.00 26.36  ? 308 GLU D N   1 
ATOM   11722 C CA  . GLU D 1 308 ? 33.182  43.443  -2.906  1.00 23.71  ? 308 GLU D CA  1 
ATOM   11723 C C   . GLU D 1 308 ? 31.752  43.145  -2.466  1.00 25.76  ? 308 GLU D C   1 
ATOM   11724 O O   . GLU D 1 308 ? 31.263  43.721  -1.486  1.00 24.33  ? 308 GLU D O   1 
ATOM   11725 C CB  . GLU D 1 308 ? 33.199  44.449  -4.058  1.00 28.32  ? 308 GLU D CB  1 
ATOM   11726 C CG  . GLU D 1 308 ? 32.554  45.777  -3.698  1.00 32.37  ? 308 GLU D CG  1 
ATOM   11727 C CD  . GLU D 1 308 ? 32.069  46.546  -4.911  1.00 32.64  ? 308 GLU D CD  1 
ATOM   11728 O OE1 . GLU D 1 308 ? 31.987  45.962  -6.019  1.00 33.24  ? 308 GLU D OE1 1 
ATOM   11729 O OE2 . GLU D 1 308 ? 31.765  47.739  -4.742  1.00 31.18  ? 308 GLU D OE2 1 
ATOM   11730 N N   . PHE D 1 309 ? 31.064  42.251  -3.177  1.00 22.03  ? 309 PHE D N   1 
ATOM   11731 C CA  . PHE D 1 309 ? 29.722  41.862  -2.763  1.00 20.62  ? 309 PHE D CA  1 
ATOM   11732 C C   . PHE D 1 309 ? 29.756  41.133  -1.431  1.00 24.11  ? 309 PHE D C   1 
ATOM   11733 O O   . PHE D 1 309 ? 28.983  41.448  -0.516  1.00 21.39  ? 309 PHE D O   1 
ATOM   11734 C CB  . PHE D 1 309 ? 29.074  40.979  -3.829  1.00 21.96  ? 309 PHE D CB  1 
ATOM   11735 C CG  . PHE D 1 309 ? 27.611  40.730  -3.587  1.00 22.49  ? 309 PHE D CG  1 
ATOM   11736 C CD1 . PHE D 1 309 ? 27.193  39.755  -2.693  1.00 23.99  ? 309 PHE D CD1 1 
ATOM   11737 C CD2 . PHE D 1 309 ? 26.665  41.499  -4.223  1.00 21.96  ? 309 PHE D CD2 1 
ATOM   11738 C CE1 . PHE D 1 309 ? 25.867  39.545  -2.441  1.00 24.19  ? 309 PHE D CE1 1 
ATOM   11739 C CE2 . PHE D 1 309 ? 25.326  41.289  -3.991  1.00 23.58  ? 309 PHE D CE2 1 
ATOM   11740 C CZ  . PHE D 1 309 ? 24.925  40.311  -3.102  1.00 26.01  ? 309 PHE D CZ  1 
ATOM   11741 N N   . ILE D 1 310 ? 30.625  40.116  -1.327  1.00 25.24  ? 310 ILE D N   1 
ATOM   11742 C CA  . ILE D 1 310 ? 30.781  39.363  -0.085  1.00 24.33  ? 310 ILE D CA  1 
ATOM   11743 C C   . ILE D 1 310 ? 31.099  40.300  1.079   1.00 22.70  ? 310 ILE D C   1 
ATOM   11744 O O   . ILE D 1 310 ? 30.552  40.152  2.176   1.00 25.78  ? 310 ILE D O   1 
ATOM   11745 C CB  . ILE D 1 310 ? 31.856  38.273  -0.260  1.00 23.40  ? 310 ILE D CB  1 
ATOM   11746 C CG1 . ILE D 1 310 ? 31.385  37.234  -1.293  1.00 26.17  ? 310 ILE D CG1 1 
ATOM   11747 C CG2 . ILE D 1 310 ? 32.219  37.597  1.093   1.00 18.46  ? 310 ILE D CG2 1 
ATOM   11748 C CD1 . ILE D 1 310 ? 30.038  36.575  -0.963  1.00 19.93  ? 310 ILE D CD1 1 
ATOM   11749 N N   . GLU D 1 311 ? 31.969  41.285  0.864   1.00 23.12  ? 311 GLU D N   1 
ATOM   11750 C CA  . GLU D 1 311 ? 32.320  42.178  1.969   1.00 27.65  ? 311 GLU D CA  1 
ATOM   11751 C C   . GLU D 1 311 ? 31.110  42.981  2.419   1.00 27.33  ? 311 GLU D C   1 
ATOM   11752 O O   . GLU D 1 311 ? 30.968  43.281  3.608   1.00 28.25  ? 311 GLU D O   1 
ATOM   11753 C CB  . GLU D 1 311 ? 33.486  43.092  1.565   1.00 28.51  ? 311 GLU D CB  1 
ATOM   11754 C CG  . GLU D 1 311 ? 34.071  44.035  2.662   1.00 31.25  ? 311 GLU D CG  1 
ATOM   11755 C CD  . GLU D 1 311 ? 34.196  43.414  4.056   1.00 37.17  ? 311 GLU D CD  1 
ATOM   11756 O OE1 . GLU D 1 311 ? 34.857  42.352  4.182   1.00 27.67  ? 311 GLU D OE1 1 
ATOM   11757 O OE2 . GLU D 1 311 ? 33.634  44.009  5.024   1.00 33.61  ? 311 GLU D OE2 1 
ATOM   11758 N N   . MET D 1 312 ? 30.197  43.279  1.502   1.00 22.11  ? 312 MET D N   1 
ATOM   11759 C CA  . MET D 1 312 ? 29.002  43.991  1.900   1.00 23.90  ? 312 MET D CA  1 
ATOM   11760 C C   . MET D 1 312 ? 28.085  43.126  2.753   1.00 29.38  ? 312 MET D C   1 
ATOM   11761 O O   . MET D 1 312 ? 27.450  43.635  3.682   1.00 25.54  ? 312 MET D O   1 
ATOM   11762 C CB  . MET D 1 312 ? 28.265  44.495  0.667   1.00 25.40  ? 312 MET D CB  1 
ATOM   11763 C CG  . MET D 1 312 ? 27.264  45.581  0.991   1.00 35.75  ? 312 MET D CG  1 
ATOM   11764 S SD  . MET D 1 312 ? 25.840  45.320  -0.035  1.00 52.26  ? 312 MET D SD  1 
ATOM   11765 C CE  . MET D 1 312 ? 25.468  43.656  0.529   1.00 35.21  ? 312 MET D CE  1 
ATOM   11766 N N   . ILE D 1 313 ? 27.984  41.823  2.474   1.00 27.26  ? 313 ILE D N   1 
ATOM   11767 C CA  . ILE D 1 313 ? 27.085  41.040  3.312   1.00 29.84  ? 313 ILE D CA  1 
ATOM   11768 C C   . ILE D 1 313 ? 27.695  40.861  4.699   1.00 25.69  ? 313 ILE D C   1 
ATOM   11769 O O   . ILE D 1 313 ? 26.975  40.824  5.697   1.00 28.86  ? 313 ILE D O   1 
ATOM   11770 C CB  . ILE D 1 313 ? 26.715  39.695  2.656   1.00 31.50  ? 313 ILE D CB  1 
ATOM   11771 C CG1 . ILE D 1 313 ? 27.733  38.639  2.984   1.00 25.62  ? 313 ILE D CG1 1 
ATOM   11772 C CG2 . ILE D 1 313 ? 26.628  39.808  1.137   1.00 27.48  ? 313 ILE D CG2 1 
ATOM   11773 C CD1 . ILE D 1 313 ? 27.211  37.247  2.814   1.00 35.84  ? 313 ILE D CD1 1 
ATOM   11774 N N   . ARG D 1 314 ? 29.032  40.764  4.787   1.00 26.90  ? 314 ARG D N   1 
ATOM   11775 C CA  . ARG D 1 314 ? 29.717  40.820  6.084   1.00 25.10  ? 314 ARG D CA  1 
ATOM   11776 C C   . ARG D 1 314 ? 29.417  42.128  6.801   1.00 26.15  ? 314 ARG D C   1 
ATOM   11777 O O   . ARG D 1 314 ? 29.204  42.144  8.018   1.00 26.54  ? 314 ARG D O   1 
ATOM   11778 C CB  . ARG D 1 314 ? 31.230  40.692  5.896   1.00 23.54  ? 314 ARG D CB  1 
ATOM   11779 C CG  . ARG D 1 314 ? 31.985  40.260  7.147   1.00 23.89  ? 314 ARG D CG  1 
ATOM   11780 C CD  . ARG D 1 314 ? 33.475  39.917  6.848   1.00 21.71  ? 314 ARG D CD  1 
ATOM   11781 N NE  . ARG D 1 314 ? 34.327  41.104  6.818   1.00 26.32  ? 314 ARG D NE  1 
ATOM   11782 C CZ  . ARG D 1 314 ? 34.749  41.769  7.888   1.00 25.76  ? 314 ARG D CZ  1 
ATOM   11783 N NH1 . ARG D 1 314 ? 34.439  41.381  9.114   1.00 33.87  ? 314 ARG D NH1 1 
ATOM   11784 N NH2 . ARG D 1 314 ? 35.487  42.862  7.726   1.00 28.26  ? 314 ARG D NH2 1 
ATOM   11785 N N   . THR D 1 315 ? 29.421  43.240  6.060   1.00 21.71  ? 315 THR D N   1 
ATOM   11786 C CA  . THR D 1 315 ? 29.079  44.516  6.664   1.00 26.51  ? 315 THR D CA  1 
ATOM   11787 C C   . THR D 1 315 ? 27.676  44.495  7.265   1.00 30.00  ? 315 THR D C   1 
ATOM   11788 O O   . THR D 1 315 ? 27.463  45.045  8.352   1.00 29.54  ? 315 THR D O   1 
ATOM   11789 C CB  . THR D 1 315 ? 29.191  45.632  5.643   1.00 28.63  ? 315 THR D CB  1 
ATOM   11790 O OG1 . THR D 1 315 ? 30.553  45.756  5.222   1.00 32.82  ? 315 THR D OG1 1 
ATOM   11791 C CG2 . THR D 1 315 ? 28.751  46.932  6.247   1.00 29.79  ? 315 THR D CG2 1 
ATOM   11792 N N   . ILE D 1 316 ? 26.695  43.885  6.581   1.00 28.88  ? 316 ILE D N   1 
ATOM   11793 C CA  . ILE D 1 316 ? 25.335  43.904  7.122   1.00 27.81  ? 316 ILE D CA  1 
ATOM   11794 C C   . ILE D 1 316 ? 25.123  42.875  8.219   1.00 29.58  ? 316 ILE D C   1 
ATOM   11795 O O   . ILE D 1 316 ? 24.036  42.836  8.809   1.00 23.79  ? 316 ILE D O   1 
ATOM   11796 C CB  . ILE D 1 316 ? 24.241  43.762  6.045   1.00 33.85  ? 316 ILE D CB  1 
ATOM   11797 C CG1 . ILE D 1 316 ? 24.075  42.344  5.543   1.00 36.22  ? 316 ILE D CG1 1 
ATOM   11798 C CG2 . ILE D 1 316 ? 24.510  44.715  4.874   1.00 36.91  ? 316 ILE D CG2 1 
ATOM   11799 C CD1 . ILE D 1 316 ? 23.322  42.315  4.229   1.00 37.20  ? 316 ILE D CD1 1 
ATOM   11800 N N   . GLY D 1 317 ? 26.131  42.061  8.535   1.00 29.79  ? 317 GLY D N   1 
ATOM   11801 C CA  . GLY D 1 317 ? 26.102  41.269  9.756   1.00 27.79  ? 317 GLY D CA  1 
ATOM   11802 C C   . GLY D 1 317 ? 26.154  39.767  9.597   1.00 27.11  ? 317 GLY D C   1 
ATOM   11803 O O   . GLY D 1 317 ? 26.053  39.058  10.606  1.00 27.93  ? 317 GLY D O   1 
ATOM   11804 N N   . TYR D 1 318 ? 26.308  39.206  8.410   1.00 25.59  ? 318 TYR D N   1 
ATOM   11805 C CA  . TYR D 1 318 ? 26.303  37.756  8.298   1.00 25.24  ? 318 TYR D CA  1 
ATOM   11806 C C   . TYR D 1 318 ? 27.634  37.185  8.792   1.00 25.98  ? 318 TYR D C   1 
ATOM   11807 O O   . TYR D 1 318 ? 28.703  37.716  8.479   1.00 20.85  ? 318 TYR D O   1 
ATOM   11808 C CB  . TYR D 1 318 ? 26.023  37.322  6.855   1.00 23.14  ? 318 TYR D CB  1 
ATOM   11809 C CG  . TYR D 1 318 ? 26.028  35.825  6.735   1.00 23.03  ? 318 TYR D CG  1 
ATOM   11810 C CD1 . TYR D 1 318 ? 25.070  35.061  7.376   1.00 19.50  ? 318 TYR D CD1 1 
ATOM   11811 C CD2 . TYR D 1 318 ? 27.039  35.173  6.044   1.00 24.39  ? 318 TYR D CD2 1 
ATOM   11812 C CE1 . TYR D 1 318 ? 25.101  33.679  7.301   1.00 28.17  ? 318 TYR D CE1 1 
ATOM   11813 C CE2 . TYR D 1 318 ? 27.087  33.786  5.960   1.00 22.75  ? 318 TYR D CE2 1 
ATOM   11814 C CZ  . TYR D 1 318 ? 26.121  33.044  6.585   1.00 27.91  ? 318 TYR D CZ  1 
ATOM   11815 O OH  . TYR D 1 318 ? 26.166  31.667  6.506   1.00 23.62  ? 318 TYR D OH  1 
ATOM   11816 N N   . ARG D 1 319 ? 27.559  36.133  9.610   1.00 23.45  ? 319 ARG D N   1 
ATOM   11817 C CA  . ARG D 1 319 ? 28.732  35.427  10.104  1.00 25.72  ? 319 ARG D CA  1 
ATOM   11818 C C   . ARG D 1 319 ? 28.578  33.944  9.787   1.00 25.31  ? 319 ARG D C   1 
ATOM   11819 O O   . ARG D 1 319 ? 27.510  33.364  9.996   1.00 21.10  ? 319 ARG D O   1 
ATOM   11820 C CB  . ARG D 1 319 ? 28.931  35.630  11.620  1.00 23.10  ? 319 ARG D CB  1 
ATOM   11821 C CG  . ARG D 1 319 ? 29.033  37.108  12.087  1.00 26.39  ? 319 ARG D CG  1 
ATOM   11822 C CD  . ARG D 1 319 ? 30.242  37.835  11.486  1.00 26.65  ? 319 ARG D CD  1 
ATOM   11823 N NE  . ARG D 1 319 ? 30.260  39.258  11.805  1.00 27.48  ? 319 ARG D NE  1 
ATOM   11824 C CZ  . ARG D 1 319 ? 29.886  40.231  10.979  1.00 29.27  ? 319 ARG D CZ  1 
ATOM   11825 N NH1 . ARG D 1 319 ? 29.455  39.978  9.752   1.00 23.09  ? 319 ARG D NH1 1 
ATOM   11826 N NH2 . ARG D 1 319 ? 29.942  41.494  11.396  1.00 33.70  ? 319 ARG D NH2 1 
ATOM   11827 N N   . GLY D 1 320 ? 29.648  33.331  9.288   1.00 22.02  ? 320 GLY D N   1 
ATOM   11828 C CA  . GLY D 1 320 ? 29.562  31.951  8.855   1.00 21.46  ? 320 GLY D CA  1 
ATOM   11829 C C   . GLY D 1 320 ? 29.904  31.770  7.390   1.00 25.53  ? 320 GLY D C   1 
ATOM   11830 O O   . GLY D 1 320 ? 30.576  32.628  6.806   1.00 24.34  ? 320 GLY D O   1 
ATOM   11831 N N   . TYR D 1 321 ? 29.443  30.675  6.778   1.00 20.33  ? 321 TYR D N   1 
ATOM   11832 C CA  . TYR D 1 321 ? 29.794  30.351  5.407   1.00 21.05  ? 321 TYR D CA  1 
ATOM   11833 C C   . TYR D 1 321 ? 28.799  30.947  4.417   1.00 23.03  ? 321 TYR D C   1 
ATOM   11834 O O   . TYR D 1 321 ? 27.588  30.929  4.650   1.00 18.00  ? 321 TYR D O   1 
ATOM   11835 C CB  . TYR D 1 321 ? 29.874  28.831  5.228   1.00 21.37  ? 321 TYR D CB  1 
ATOM   11836 C CG  . TYR D 1 321 ? 31.027  28.286  6.014   1.00 21.16  ? 321 TYR D CG  1 
ATOM   11837 C CD1 . TYR D 1 321 ? 32.312  28.291  5.481   1.00 19.57  ? 321 TYR D CD1 1 
ATOM   11838 C CD2 . TYR D 1 321 ? 30.855  27.835  7.309   1.00 20.75  ? 321 TYR D CD2 1 
ATOM   11839 C CE1 . TYR D 1 321 ? 33.402  27.833  6.211   1.00 19.13  ? 321 TYR D CE1 1 
ATOM   11840 C CE2 . TYR D 1 321 ? 31.950  27.382  8.059   1.00 20.98  ? 321 TYR D CE2 1 
ATOM   11841 C CZ  . TYR D 1 321 ? 33.208  27.382  7.493   1.00 21.16  ? 321 TYR D CZ  1 
ATOM   11842 O OH  . TYR D 1 321 ? 34.283  26.935  8.219   1.00 33.05  ? 321 TYR D OH  1 
ATOM   11843 N N   . VAL D 1 322 ? 29.331  31.451  3.297   1.00 21.44  ? 322 VAL D N   1 
ATOM   11844 C CA  . VAL D 1 322 ? 28.530  31.970  2.198   1.00 21.30  ? 322 VAL D CA  1 
ATOM   11845 C C   . VAL D 1 322 ? 29.250  31.686  0.880   1.00 24.58  ? 322 VAL D C   1 
ATOM   11846 O O   . VAL D 1 322 ? 30.480  31.644  0.820   1.00 22.59  ? 322 VAL D O   1 
ATOM   11847 C CB  . VAL D 1 322 ? 28.236  33.485  2.389   1.00 24.58  ? 322 VAL D CB  1 
ATOM   11848 C CG1 . VAL D 1 322 ? 29.474  34.291  2.254   1.00 20.20  ? 322 VAL D CG1 1 
ATOM   11849 C CG2 . VAL D 1 322 ? 27.177  33.962  1.391   1.00 21.11  ? 322 VAL D CG2 1 
ATOM   11850 N N   . ASN D 1 323 ? 28.472  31.456  -0.184  1.00 25.52  ? 323 ASN D N   1 
ATOM   11851 C CA  . ASN D 1 323 ? 29.039  31.229  -1.503  1.00 23.88  ? 323 ASN D CA  1 
ATOM   11852 C C   . ASN D 1 323 ? 28.250  32.013  -2.539  1.00 27.01  ? 323 ASN D C   1 
ATOM   11853 O O   . ASN D 1 323 ? 27.066  32.307  -2.343  1.00 25.97  ? 323 ASN D O   1 
ATOM   11854 C CB  . ASN D 1 323 ? 29.078  29.723  -1.853  1.00 25.03  ? 323 ASN D CB  1 
ATOM   11855 C CG  . ASN D 1 323 ? 27.704  29.096  -1.893  1.00 28.68  ? 323 ASN D CG  1 
ATOM   11856 O OD1 . ASN D 1 323 ? 27.257  28.459  -0.922  1.00 31.02  ? 323 ASN D OD1 1 
ATOM   11857 N ND2 . ASN D 1 323 ? 27.031  29.251  -3.011  1.00 22.42  ? 323 ASN D ND2 1 
ATOM   11858 N N   . ILE D 1 324 ? 28.918  32.348  -3.648  1.00 22.30  ? 324 ILE D N   1 
ATOM   11859 C CA  . ILE D 1 324 ? 28.315  33.099  -4.748  1.00 27.55  ? 324 ILE D CA  1 
ATOM   11860 C C   . ILE D 1 324 ? 28.540  32.344  -6.063  1.00 24.50  ? 324 ILE D C   1 
ATOM   11861 O O   . ILE D 1 324 ? 29.684  32.048  -6.419  1.00 29.73  ? 324 ILE D O   1 
ATOM   11862 C CB  . ILE D 1 324 ? 28.861  34.542  -4.808  1.00 26.10  ? 324 ILE D CB  1 
ATOM   11863 C CG1 . ILE D 1 324 ? 28.284  35.319  -5.992  1.00 27.63  ? 324 ILE D CG1 1 
ATOM   11864 C CG2 . ILE D 1 324 ? 30.399  34.589  -4.811  1.00 27.16  ? 324 ILE D CG2 1 
ATOM   11865 C CD1 . ILE D 1 324 ? 28.010  36.790  -5.663  1.00 28.53  ? 324 ILE D CD1 1 
ATOM   11866 N N   . ASP D 1 325 ? 27.447  31.996  -6.752  1.00 30.88  ? 325 ASP D N   1 
ATOM   11867 C CA  . ASP D 1 325 ? 27.473  31.383  -8.085  1.00 33.55  ? 325 ASP D CA  1 
ATOM   11868 C C   . ASP D 1 325 ? 27.727  32.438  -9.152  1.00 30.35  ? 325 ASP D C   1 
ATOM   11869 O O   . ASP D 1 325 ? 27.272  33.580  -9.033  1.00 29.91  ? 325 ASP D O   1 
ATOM   11870 C CB  . ASP D 1 325 ? 26.127  30.742  -8.464  1.00 35.42  ? 325 ASP D CB  1 
ATOM   11871 C CG  . ASP D 1 325 ? 25.788  29.516  -7.668  1.00 50.66  ? 325 ASP D CG  1 
ATOM   11872 O OD1 . ASP D 1 325 ? 26.539  28.514  -7.731  1.00 55.47  ? 325 ASP D OD1 1 
ATOM   11873 O OD2 . ASP D 1 325 ? 24.717  29.534  -7.019  1.00 56.07  ? 325 ASP D OD2 1 
ATOM   11874 N N   . GLY D 1 326 ? 28.347  32.019  -10.249 1.00 26.52  ? 326 GLY D N   1 
ATOM   11875 C CA  . GLY D 1 326 ? 28.514  32.917  -11.380 1.00 27.94  ? 326 GLY D CA  1 
ATOM   11876 C C   . GLY D 1 326 ? 28.934  32.187  -12.639 1.00 27.64  ? 326 GLY D C   1 
ATOM   11877 O O   . GLY D 1 326 ? 29.086  30.964  -12.665 1.00 29.36  ? 326 GLY D O   1 
ATOM   11878 N N   . ILE D 1 327 ? 29.138  32.969  -13.696 1.00 29.15  ? 327 ILE D N   1 
ATOM   11879 C CA  . ILE D 1 327 ? 29.495  32.436  -15.002 1.00 32.20  ? 327 ILE D CA  1 
ATOM   11880 C C   . ILE D 1 327 ? 30.384  33.439  -15.729 1.00 33.28  ? 327 ILE D C   1 
ATOM   11881 O O   . ILE D 1 327 ? 30.379  34.641  -15.436 1.00 31.52  ? 327 ILE D O   1 
ATOM   11882 C CB  . ILE D 1 327 ? 28.253  32.115  -15.874 1.00 32.82  ? 327 ILE D CB  1 
ATOM   11883 C CG1 . ILE D 1 327 ? 27.455  33.392  -16.158 1.00 32.78  ? 327 ILE D CG1 1 
ATOM   11884 C CG2 . ILE D 1 327 ? 27.357  31.073  -15.218 1.00 30.41  ? 327 ILE D CG2 1 
ATOM   11885 C CD1 . ILE D 1 327 ? 26.356  33.181  -17.169 1.00 29.87  ? 327 ILE D CD1 1 
ATOM   11886 N N   . VAL D 1 328 ? 31.144  32.930  -16.699 1.00 32.09  ? 328 VAL D N   1 
ATOM   11887 C CA  . VAL D 1 328 ? 31.885  33.753  -17.647 1.00 37.31  ? 328 VAL D CA  1 
ATOM   11888 C C   . VAL D 1 328 ? 31.439  33.373  -19.051 1.00 43.43  ? 328 VAL D C   1 
ATOM   11889 O O   . VAL D 1 328 ? 31.331  32.183  -19.371 1.00 42.03  ? 328 VAL D O   1 
ATOM   11890 C CB  . VAL D 1 328 ? 33.407  33.581  -17.499 1.00 42.33  ? 328 VAL D CB  1 
ATOM   11891 C CG1 . VAL D 1 328 ? 34.148  34.482  -18.503 1.00 38.32  ? 328 VAL D CG1 1 
ATOM   11892 C CG2 . VAL D 1 328 ? 33.846  33.873  -16.051 1.00 39.15  ? 328 VAL D CG2 1 
ATOM   11893 N N   . LEU D 1 329 ? 31.179  34.381  -19.881 1.00 42.58  ? 329 LEU D N   1 
ATOM   11894 C CA  . LEU D 1 329 ? 30.834  34.152  -21.276 1.00 48.00  ? 329 LEU D CA  1 
ATOM   11895 C C   . LEU D 1 329 ? 32.099  34.129  -22.143 1.00 47.74  ? 329 LEU D C   1 
ATOM   11896 O O   . LEU D 1 329 ? 33.163  34.624  -21.756 1.00 48.70  ? 329 LEU D O   1 
ATOM   11897 C CB  . LEU D 1 329 ? 29.861  35.228  -21.777 1.00 41.29  ? 329 LEU D CB  1 
ATOM   11898 C CG  . LEU D 1 329 ? 28.529  35.435  -21.039 1.00 40.64  ? 329 LEU D CG  1 
ATOM   11899 C CD1 . LEU D 1 329 ? 27.555  36.198  -21.906 1.00 44.20  ? 329 LEU D CD1 1 
ATOM   11900 C CD2 . LEU D 1 329 ? 27.902  34.130  -20.573 1.00 39.55  ? 329 LEU D CD2 1 
ATOM   11901 N N   . ASP D 1 330 ? 31.964  33.537  -23.333 1.00 48.61  ? 330 ASP D N   1 
ATOM   11902 C CA  . ASP D 1 330 ? 33.062  33.515  -24.299 1.00 51.28  ? 330 ASP D CA  1 
ATOM   11903 C C   . ASP D 1 330 ? 33.586  34.919  -24.581 1.00 47.81  ? 330 ASP D C   1 
ATOM   11904 O O   . ASP D 1 330 ? 34.798  35.120  -24.720 1.00 48.14  ? 330 ASP D O   1 
ATOM   11905 C CB  . ASP D 1 330 ? 32.599  32.848  -25.598 1.00 49.28  ? 330 ASP D CB  1 
ATOM   11906 C CG  . ASP D 1 330 ? 31.891  31.520  -25.359 1.00 56.62  ? 330 ASP D CG  1 
ATOM   11907 O OD1 . ASP D 1 330 ? 31.058  31.447  -24.431 1.00 60.86  ? 330 ASP D OD1 1 
ATOM   11908 O OD2 . ASP D 1 330 ? 32.147  30.553  -26.111 1.00 65.12  ? 330 ASP D OD2 1 
ATOM   11909 N N   . ASP D 1 331 ? 32.688  35.909  -24.654 1.00 43.70  ? 331 ASP D N   1 
ATOM   11910 C CA  . ASP D 1 331 ? 33.091  37.296  -24.875 1.00 43.01  ? 331 ASP D CA  1 
ATOM   11911 C C   . ASP D 1 331 ? 33.783  37.914  -23.664 1.00 46.82  ? 331 ASP D C   1 
ATOM   11912 O O   . ASP D 1 331 ? 34.104  39.109  -23.695 1.00 47.16  ? 331 ASP D O   1 
ATOM   11913 C CB  . ASP D 1 331 ? 31.875  38.147  -25.292 1.00 45.41  ? 331 ASP D CB  1 
ATOM   11914 C CG  . ASP D 1 331 ? 30.839  38.327  -24.168 1.00 48.47  ? 331 ASP D CG  1 
ATOM   11915 O OD1 . ASP D 1 331 ? 31.102  37.913  -23.022 1.00 48.52  ? 331 ASP D OD1 1 
ATOM   11916 O OD2 . ASP D 1 331 ? 29.742  38.879  -24.434 1.00 46.43  ? 331 ASP D OD2 1 
ATOM   11917 N N   . GLY D 1 332 ? 33.999  37.145  -22.594 1.00 47.76  ? 332 GLY D N   1 
ATOM   11918 C CA  . GLY D 1 332 ? 34.671  37.647  -21.416 1.00 49.55  ? 332 GLY D CA  1 
ATOM   11919 C C   . GLY D 1 332 ? 33.784  38.341  -20.400 1.00 45.60  ? 332 GLY D C   1 
ATOM   11920 O O   . GLY D 1 332 ? 34.282  38.719  -19.334 1.00 45.99  ? 332 GLY D O   1 
ATOM   11921 N N   . ARG D 1 333 ? 32.498  38.526  -20.692 1.00 42.77  ? 333 ARG D N   1 
ATOM   11922 C CA  . ARG D 1 333 ? 31.596  39.112  -19.712 1.00 42.64  ? 333 ARG D CA  1 
ATOM   11923 C C   . ARG D 1 333 ? 31.375  38.147  -18.547 1.00 38.76  ? 333 ARG D C   1 
ATOM   11924 O O   . ARG D 1 333 ? 31.373  36.927  -18.709 1.00 35.65  ? 333 ARG D O   1 
ATOM   11925 C CB  . ARG D 1 333 ? 30.258  39.479  -20.361 1.00 40.32  ? 333 ARG D CB  1 
ATOM   11926 C CG  . ARG D 1 333 ? 30.331  40.649  -21.337 1.00 40.28  ? 333 ARG D CG  1 
ATOM   11927 C CD  . ARG D 1 333 ? 28.949  41.118  -21.768 1.00 40.08  ? 333 ARG D CD  1 
ATOM   11928 N NE  . ARG D 1 333 ? 28.282  40.135  -22.614 1.00 45.54  ? 333 ARG D NE  1 
ATOM   11929 C CZ  . ARG D 1 333 ? 26.972  40.082  -22.817 1.00 47.19  ? 333 ARG D CZ  1 
ATOM   11930 N NH1 . ARG D 1 333 ? 26.148  40.950  -22.246 1.00 45.05  ? 333 ARG D NH1 1 
ATOM   11931 N NH2 . ARG D 1 333 ? 26.477  39.138  -23.617 1.00 45.93  ? 333 ARG D NH2 1 
ATOM   11932 N N   . VAL D 1 334 ? 31.198  38.717  -17.362 1.00 39.99  ? 334 VAL D N   1 
ATOM   11933 C CA  . VAL D 1 334 ? 31.031  37.966  -16.127 1.00 37.57  ? 334 VAL D CA  1 
ATOM   11934 C C   . VAL D 1 334 ? 29.666  38.298  -15.530 1.00 37.38  ? 334 VAL D C   1 
ATOM   11935 O O   . VAL D 1 334 ? 29.252  39.466  -15.516 1.00 34.96  ? 334 VAL D O   1 
ATOM   11936 C CB  . VAL D 1 334 ? 32.167  38.290  -15.134 1.00 36.28  ? 334 VAL D CB  1 
ATOM   11937 C CG1 . VAL D 1 334 ? 31.806  37.810  -13.725 1.00 30.65  ? 334 VAL D CG1 1 
ATOM   11938 C CG2 . VAL D 1 334 ? 33.481  37.675  -15.609 1.00 34.14  ? 334 VAL D CG2 1 
ATOM   11939 N N   . PHE D 1 335 ? 28.958  37.265  -15.060 1.00 29.22  ? 335 PHE D N   1 
ATOM   11940 C CA  . PHE D 1 335 ? 27.698  37.435  -14.356 1.00 26.73  ? 335 PHE D CA  1 
ATOM   11941 C C   . PHE D 1 335 ? 27.720  36.635  -13.065 1.00 28.81  ? 335 PHE D C   1 
ATOM   11942 O O   . PHE D 1 335 ? 28.175  35.492  -13.046 1.00 30.94  ? 335 PHE D O   1 
ATOM   11943 C CB  . PHE D 1 335 ? 26.516  36.972  -15.202 1.00 30.54  ? 335 PHE D CB  1 
ATOM   11944 C CG  . PHE D 1 335 ? 26.186  37.886  -16.341 1.00 36.98  ? 335 PHE D CG  1 
ATOM   11945 C CD1 . PHE D 1 335 ? 25.532  39.086  -16.117 1.00 31.19  ? 335 PHE D CD1 1 
ATOM   11946 C CD2 . PHE D 1 335 ? 26.515  37.538  -17.645 1.00 34.46  ? 335 PHE D CD2 1 
ATOM   11947 C CE1 . PHE D 1 335 ? 25.223  39.915  -17.161 1.00 31.94  ? 335 PHE D CE1 1 
ATOM   11948 C CE2 . PHE D 1 335 ? 26.197  38.375  -18.691 1.00 36.49  ? 335 PHE D CE2 1 
ATOM   11949 C CZ  . PHE D 1 335 ? 25.559  39.559  -18.450 1.00 32.12  ? 335 PHE D CZ  1 
ATOM   11950 N N   . PHE D 1 336 ? 27.215  37.229  -11.991 1.00 29.94  ? 336 PHE D N   1 
ATOM   11951 C CA  . PHE D 1 336 ? 26.933  36.506  -10.760 1.00 24.94  ? 336 PHE D CA  1 
ATOM   11952 C C   . PHE D 1 336 ? 25.428  36.306  -10.622 1.00 32.62  ? 336 PHE D C   1 
ATOM   11953 O O   . PHE D 1 336 ? 24.638  37.214  -10.922 1.00 34.76  ? 336 PHE D O   1 
ATOM   11954 C CB  . PHE D 1 336 ? 27.482  37.249  -9.553  1.00 25.76  ? 336 PHE D CB  1 
ATOM   11955 C CG  . PHE D 1 336 ? 28.965  37.476  -9.600  1.00 25.33  ? 336 PHE D CG  1 
ATOM   11956 C CD1 . PHE D 1 336 ? 29.849  36.457  -9.290  1.00 29.37  ? 336 PHE D CD1 1 
ATOM   11957 C CD2 . PHE D 1 336 ? 29.482  38.724  -9.944  1.00 25.54  ? 336 PHE D CD2 1 
ATOM   11958 C CE1 . PHE D 1 336 ? 31.231  36.679  -9.321  1.00 27.02  ? 336 PHE D CE1 1 
ATOM   11959 C CE2 . PHE D 1 336 ? 30.862  38.947  -9.977  1.00 25.54  ? 336 PHE D CE2 1 
ATOM   11960 C CZ  . PHE D 1 336 ? 31.734  37.936  -9.665  1.00 22.82  ? 336 PHE D CZ  1 
ATOM   11961 N N   . HIS D 1 337 ? 25.034  35.115  -10.163 1.00 31.30  ? 337 HIS D N   1 
ATOM   11962 C CA  . HIS D 1 337 ? 23.643  34.671  -10.229 1.00 33.95  ? 337 HIS D CA  1 
ATOM   11963 C C   . HIS D 1 337 ? 22.933  34.611  -8.888  1.00 33.53  ? 337 HIS D C   1 
ATOM   11964 O O   . HIS D 1 337 ? 21.715  34.817  -8.846  1.00 29.28  ? 337 HIS D O   1 
ATOM   11965 C CB  . HIS D 1 337 ? 23.555  33.276  -10.868 1.00 33.56  ? 337 HIS D CB  1 
ATOM   11966 C CG  . HIS D 1 337 ? 23.803  33.258  -12.347 1.00 38.02  ? 337 HIS D CG  1 
ATOM   11967 N ND1 . HIS D 1 337 ? 23.465  34.306  -13.177 1.00 36.78  ? 337 HIS D ND1 1 
ATOM   11968 C CD2 . HIS D 1 337 ? 24.348  32.308  -13.145 1.00 34.53  ? 337 HIS D CD2 1 
ATOM   11969 C CE1 . HIS D 1 337 ? 23.796  34.006  -14.421 1.00 31.62  ? 337 HIS D CE1 1 
ATOM   11970 N NE2 . HIS D 1 337 ? 24.330  32.798  -14.428 1.00 35.75  ? 337 HIS D NE2 1 
ATOM   11971 N N   . GLU D 1 338 ? 23.642  34.301  -7.801  1.00 32.39  ? 338 GLU D N   1 
ATOM   11972 C CA  . GLU D 1 338 ? 22.966  34.122  -6.517  1.00 36.63  ? 338 GLU D CA  1 
ATOM   11973 C C   . GLU D 1 338 ? 23.974  33.827  -5.413  1.00 32.94  ? 338 GLU D C   1 
ATOM   11974 O O   . GLU D 1 338 ? 25.126  33.439  -5.658  1.00 29.01  ? 338 GLU D O   1 
ATOM   11975 C CB  . GLU D 1 338 ? 21.919  32.997  -6.562  1.00 34.73  ? 338 GLU D CB  1 
ATOM   11976 C CG  . GLU D 1 338 ? 22.464  31.671  -6.968  1.00 38.46  ? 338 GLU D CG  1 
ATOM   11977 C CD  . GLU D 1 338 ? 21.548  30.510  -6.599  1.00 47.32  ? 338 GLU D CD  1 
ATOM   11978 O OE1 . GLU D 1 338 ? 20.311  30.698  -6.582  1.00 43.02  ? 338 GLU D OE1 1 
ATOM   11979 O OE2 . GLU D 1 338 ? 22.076  29.401  -6.336  1.00 53.75  ? 338 GLU D OE2 1 
ATOM   11980 N N   . ILE D 1 339 ? 23.506  34.015  -4.185  1.00 28.27  ? 339 ILE D N   1 
ATOM   11981 C CA  . ILE D 1 339 ? 24.279  33.715  -2.990  1.00 31.48  ? 339 ILE D CA  1 
ATOM   11982 C C   . ILE D 1 339 ? 23.500  32.727  -2.139  1.00 29.91  ? 339 ILE D C   1 
ATOM   11983 O O   . ILE D 1 339 ? 22.268  32.662  -2.191  1.00 29.55  ? 339 ILE D O   1 
ATOM   11984 C CB  . ILE D 1 339 ? 24.615  34.981  -2.173  1.00 27.09  ? 339 ILE D CB  1 
ATOM   11985 C CG1 . ILE D 1 339 ? 23.335  35.724  -1.816  1.00 27.23  ? 339 ILE D CG1 1 
ATOM   11986 C CG2 . ILE D 1 339 ? 25.640  35.877  -2.913  1.00 22.19  ? 339 ILE D CG2 1 
ATOM   11987 C CD1 . ILE D 1 339 ? 23.459  36.492  -0.530  1.00 29.54  ? 339 ILE D CD1 1 
ATOM   11988 N N   . ASN D 1 340 ? 24.239  31.945  -1.359  1.00 28.07  ? 340 ASN D N   1 
ATOM   11989 C CA  . ASN D 1 340 ? 23.670  31.059  -0.358  1.00 24.01  ? 340 ASN D CA  1 
ATOM   11990 C C   . ASN D 1 340 ? 24.438  31.289  0.926   1.00 28.18  ? 340 ASN D C   1 
ATOM   11991 O O   . ASN D 1 340 ? 25.657  31.076  0.966   1.00 25.05  ? 340 ASN D O   1 
ATOM   11992 C CB  . ASN D 1 340 ? 23.743  29.591  -0.788  1.00 25.96  ? 340 ASN D CB  1 
ATOM   11993 C CG  . ASN D 1 340 ? 23.236  29.385  -2.190  1.00 35.71  ? 340 ASN D CG  1 
ATOM   11994 O OD1 . ASN D 1 340 ? 22.050  29.542  -2.456  1.00 30.27  ? 340 ASN D OD1 1 
ATOM   11995 N ND2 . ASN D 1 340 ? 24.138  29.061  -3.104  1.00 42.28  ? 340 ASN D ND2 1 
ATOM   11996 N N   . ALA D 1 341 ? 23.723  31.756  1.957   1.00 29.48  ? 341 ALA D N   1 
ATOM   11997 C CA  . ALA D 1 341 ? 24.266  31.949  3.297   1.00 26.26  ? 341 ALA D CA  1 
ATOM   11998 C C   . ALA D 1 341 ? 24.011  30.662  4.061   1.00 23.73  ? 341 ALA D C   1 
ATOM   11999 O O   . ALA D 1 341 ? 23.001  30.519  4.746   1.00 20.16  ? 341 ALA D O   1 
ATOM   12000 C CB  . ALA D 1 341 ? 23.623  33.145  3.985   1.00 27.32  ? 341 ALA D CB  1 
ATOM   12001 N N   . ARG D 1 342 ? 24.950  29.722  3.919   1.00 24.02  ? 342 ARG D N   1 
ATOM   12002 C CA  . ARG D 1 342 ? 24.922  28.365  4.455   1.00 27.53  ? 342 ARG D CA  1 
ATOM   12003 C C   . ARG D 1 342 ? 26.047  27.562  3.796   1.00 29.99  ? 342 ARG D C   1 
ATOM   12004 O O   . ARG D 1 342 ? 26.593  27.991  2.767   1.00 25.00  ? 342 ARG D O   1 
ATOM   12005 C CB  . ARG D 1 342 ? 23.569  27.692  4.205   1.00 23.92  ? 342 ARG D CB  1 
ATOM   12006 C CG  . ARG D 1 342 ? 23.201  27.537  2.726   1.00 28.69  ? 342 ARG D CG  1 
ATOM   12007 C CD  . ARG D 1 342 ? 21.743  27.056  2.587   1.00 35.92  ? 342 ARG D CD  1 
ATOM   12008 N NE  . ARG D 1 342 ? 21.543  26.194  1.430   1.00 43.34  ? 342 ARG D NE  1 
ATOM   12009 C CZ  . ARG D 1 342 ? 21.825  24.895  1.395   1.00 53.52  ? 342 ARG D CZ  1 
ATOM   12010 N NH1 . ARG D 1 342 ? 22.334  24.264  2.447   1.00 47.10  ? 342 ARG D NH1 1 
ATOM   12011 N NH2 . ARG D 1 342 ? 21.592  24.212  0.275   1.00 51.41  ? 342 ARG D NH2 1 
ATOM   12012 N N   . TRP D 1 343 ? 26.388  26.393  4.345   1.00 26.08  ? 343 TRP D N   1 
ATOM   12013 C CA  . TRP D 1 343 ? 27.381  25.555  3.684   1.00 28.85  ? 343 TRP D CA  1 
ATOM   12014 C C   . TRP D 1 343 ? 27.001  25.346  2.222   1.00 31.83  ? 343 TRP D C   1 
ATOM   12015 O O   . TRP D 1 343 ? 25.838  25.096  1.898   1.00 31.40  ? 343 TRP D O   1 
ATOM   12016 C CB  . TRP D 1 343 ? 27.502  24.180  4.350   1.00 24.51  ? 343 TRP D CB  1 
ATOM   12017 C CG  . TRP D 1 343 ? 27.808  24.166  5.802   1.00 25.86  ? 343 TRP D CG  1 
ATOM   12018 C CD1 . TRP D 1 343 ? 28.401  25.154  6.541   1.00 23.77  ? 343 TRP D CD1 1 
ATOM   12019 C CD2 . TRP D 1 343 ? 27.550  23.092  6.701   1.00 23.17  ? 343 TRP D CD2 1 
ATOM   12020 N NE1 . TRP D 1 343 ? 28.534  24.751  7.848   1.00 24.83  ? 343 TRP D NE1 1 
ATOM   12021 C CE2 . TRP D 1 343 ? 28.024  23.486  7.973   1.00 25.30  ? 343 TRP D CE2 1 
ATOM   12022 C CE3 . TRP D 1 343 ? 26.978  21.824  6.555   1.00 23.25  ? 343 TRP D CE3 1 
ATOM   12023 C CZ2 . TRP D 1 343 ? 27.907  22.674  9.098   1.00 25.66  ? 343 TRP D CZ2 1 
ATOM   12024 C CZ3 . TRP D 1 343 ? 26.884  21.013  7.678   1.00 27.62  ? 343 TRP D CZ3 1 
ATOM   12025 C CH2 . TRP D 1 343 ? 27.341  21.447  8.933   1.00 21.68  ? 343 TRP D CH2 1 
ATOM   12026 N N   . SER D 1 344 ? 27.987  25.444  1.340   1.00 24.93  ? 344 SER D N   1 
ATOM   12027 C CA  . SER D 1 344 ? 27.771  24.950  -0.004  1.00 26.84  ? 344 SER D CA  1 
ATOM   12028 C C   . SER D 1 344 ? 27.802  23.427  0.011   1.00 29.82  ? 344 SER D C   1 
ATOM   12029 O O   . SER D 1 344 ? 28.104  22.796  1.024   1.00 30.85  ? 344 SER D O   1 
ATOM   12030 C CB  . SER D 1 344 ? 28.814  25.516  -0.958  1.00 23.01  ? 344 SER D CB  1 
ATOM   12031 O OG  . SER D 1 344 ? 30.041  24.816  -0.822  1.00 29.45  ? 344 SER D OG  1 
ATOM   12032 N N   . GLY D 1 345 ? 27.454  22.830  -1.126  1.00 35.70  ? 345 GLY D N   1 
ATOM   12033 C CA  . GLY D 1 345 ? 27.596  21.390  -1.261  1.00 28.62  ? 345 GLY D CA  1 
ATOM   12034 C C   . GLY D 1 345 ? 29.045  20.934  -1.222  1.00 27.89  ? 345 GLY D C   1 
ATOM   12035 O O   . GLY D 1 345 ? 29.334  19.821  -0.775  1.00 26.37  ? 345 GLY D O   1 
ATOM   12036 N N   . GLY D 1 346 ? 29.970  21.786  -1.663  1.00 24.23  ? 346 GLY D N   1 
ATOM   12037 C CA  . GLY D 1 346 ? 31.376  21.445  -1.752  1.00 27.78  ? 346 GLY D CA  1 
ATOM   12038 C C   . GLY D 1 346 ? 32.255  21.833  -0.575  1.00 27.93  ? 346 GLY D C   1 
ATOM   12039 O O   . GLY D 1 346 ? 33.484  21.728  -0.682  1.00 29.20  ? 346 GLY D O   1 
ATOM   12040 N N   . LEU D 1 347 ? 31.678  22.272  0.545   1.00 26.51  ? 347 LEU D N   1 
ATOM   12041 C CA  . LEU D 1 347 ? 32.501  22.704  1.666   1.00 24.66  ? 347 LEU D CA  1 
ATOM   12042 C C   . LEU D 1 347 ? 33.203  21.521  2.311   1.00 24.23  ? 347 LEU D C   1 
ATOM   12043 O O   . LEU D 1 347 ? 34.361  21.639  2.715   1.00 24.79  ? 347 LEU D O   1 
ATOM   12044 C CB  . LEU D 1 347 ? 31.660  23.462  2.707   1.00 24.17  ? 347 LEU D CB  1 
ATOM   12045 C CG  . LEU D 1 347 ? 32.392  23.940  3.973   1.00 20.76  ? 347 LEU D CG  1 
ATOM   12046 C CD1 . LEU D 1 347 ? 33.460  24.989  3.655   1.00 18.77  ? 347 LEU D CD1 1 
ATOM   12047 C CD2 . LEU D 1 347 ? 31.419  24.481  5.007   1.00 24.32  ? 347 LEU D CD2 1 
ATOM   12048 N N   . ILE D 1 348 ? 32.515  20.377  2.433   1.00 24.11  ? 348 ILE D N   1 
ATOM   12049 C CA  . ILE D 1 348 ? 33.188  19.180  2.935   1.00 29.65  ? 348 ILE D CA  1 
ATOM   12050 C C   . ILE D 1 348 ? 34.324  18.775  2.008   1.00 21.39  ? 348 ILE D C   1 
ATOM   12051 O O   . ILE D 1 348 ? 35.359  18.296  2.464   1.00 25.70  ? 348 ILE D O   1 
ATOM   12052 C CB  . ILE D 1 348 ? 32.221  17.994  3.119   1.00 30.05  ? 348 ILE D CB  1 
ATOM   12053 C CG1 . ILE D 1 348 ? 30.810  18.445  3.435   1.00 35.67  ? 348 ILE D CG1 1 
ATOM   12054 C CG2 . ILE D 1 348 ? 32.748  17.085  4.242   1.00 25.63  ? 348 ILE D CG2 1 
ATOM   12055 C CD1 . ILE D 1 348 ? 30.720  19.317  4.645   1.00 42.03  ? 348 ILE D CD1 1 
ATOM   12056 N N   . TYR D 1 349 ? 34.127  18.886  0.695   1.00 23.59  ? 349 TYR D N   1 
ATOM   12057 C CA  . TYR D 1 349 ? 35.195  18.490  -0.215  1.00 21.70  ? 349 TYR D CA  1 
ATOM   12058 C C   . TYR D 1 349 ? 36.422  19.350  0.017   1.00 23.88  ? 349 TYR D C   1 
ATOM   12059 O O   . TYR D 1 349 ? 37.540  18.840  0.177   1.00 24.96  ? 349 TYR D O   1 
ATOM   12060 C CB  . TYR D 1 349 ? 34.760  18.608  -1.675  1.00 23.48  ? 349 TYR D CB  1 
ATOM   12061 C CG  . TYR D 1 349 ? 33.480  17.927  -2.099  1.00 29.21  ? 349 TYR D CG  1 
ATOM   12062 C CD1 . TYR D 1 349 ? 33.026  16.770  -1.492  1.00 27.93  ? 349 TYR D CD1 1 
ATOM   12063 C CD2 . TYR D 1 349 ? 32.731  18.451  -3.146  1.00 34.21  ? 349 TYR D CD2 1 
ATOM   12064 C CE1 . TYR D 1 349 ? 31.844  16.163  -1.915  1.00 30.78  ? 349 TYR D CE1 1 
ATOM   12065 C CE2 . TYR D 1 349 ? 31.562  17.851  -3.571  1.00 35.52  ? 349 TYR D CE2 1 
ATOM   12066 C CZ  . TYR D 1 349 ? 31.124  16.715  -2.953  1.00 34.22  ? 349 TYR D CZ  1 
ATOM   12067 O OH  . TYR D 1 349 ? 29.965  16.130  -3.403  1.00 37.49  ? 349 TYR D OH  1 
ATOM   12068 N N   . HIS D 1 350 ? 36.233  20.673  0.037   1.00 24.30  ? 350 HIS D N   1 
ATOM   12069 C CA  . HIS D 1 350 ? 37.345  21.548  0.377   1.00 25.55  ? 350 HIS D CA  1 
ATOM   12070 C C   . HIS D 1 350 ? 37.953  21.148  1.714   1.00 25.27  ? 350 HIS D C   1 
ATOM   12071 O O   . HIS D 1 350 ? 39.177  21.152  1.862   1.00 24.84  ? 350 HIS D O   1 
ATOM   12072 C CB  . HIS D 1 350 ? 36.902  23.012  0.417   1.00 21.74  ? 350 HIS D CB  1 
ATOM   12073 C CG  . HIS D 1 350 ? 37.934  23.921  0.998   1.00 18.59  ? 350 HIS D CG  1 
ATOM   12074 N ND1 . HIS D 1 350 ? 39.068  24.294  0.306   1.00 18.49  ? 350 HIS D ND1 1 
ATOM   12075 C CD2 . HIS D 1 350 ? 38.026  24.511  2.213   1.00 22.33  ? 350 HIS D CD2 1 
ATOM   12076 C CE1 . HIS D 1 350 ? 39.805  25.087  1.063   1.00 16.77  ? 350 HIS D CE1 1 
ATOM   12077 N NE2 . HIS D 1 350 ? 39.197  25.237  2.225   1.00 19.09  ? 350 HIS D NE2 1 
ATOM   12078 N N   . THR D 1 351 ? 37.109  20.774  2.688   1.00 21.55  ? 351 THR D N   1 
ATOM   12079 C CA  . THR D 1 351 ? 37.593  20.456  4.033   1.00 22.67  ? 351 THR D CA  1 
ATOM   12080 C C   . THR D 1 351 ? 38.467  19.211  4.028   1.00 22.46  ? 351 THR D C   1 
ATOM   12081 O O   . THR D 1 351 ? 39.579  19.224  4.566   1.00 27.55  ? 351 THR D O   1 
ATOM   12082 C CB  . THR D 1 351 ? 36.416  20.257  4.986   1.00 21.45  ? 351 THR D CB  1 
ATOM   12083 O OG1 . THR D 1 351 ? 35.609  21.422  4.972   1.00 25.42  ? 351 THR D OG1 1 
ATOM   12084 C CG2 . THR D 1 351 ? 36.887  19.991  6.423   1.00 24.25  ? 351 THR D CG2 1 
ATOM   12085 N N   . VAL D 1 352 ? 37.957  18.114  3.464   1.00 26.91  ? 352 VAL D N   1 
ATOM   12086 C CA  . VAL D 1 352 ? 38.764  16.904  3.294   1.00 24.07  ? 352 VAL D CA  1 
ATOM   12087 C C   . VAL D 1 352 ? 40.051  17.238  2.560   1.00 24.89  ? 352 VAL D C   1 
ATOM   12088 O O   . VAL D 1 352 ? 41.138  16.799  2.952   1.00 27.15  ? 352 VAL D O   1 
ATOM   12089 C CB  . VAL D 1 352 ? 37.967  15.818  2.541   1.00 24.93  ? 352 VAL D CB  1 
ATOM   12090 C CG1 . VAL D 1 352 ? 38.806  14.543  2.346   1.00 19.00  ? 352 VAL D CG1 1 
ATOM   12091 C CG2 . VAL D 1 352 ? 36.651  15.492  3.258   1.00 25.46  ? 352 VAL D CG2 1 
ATOM   12092 N N   . ALA D 1 353 ? 39.947  18.034  1.494   1.00 23.38  ? 353 ALA D N   1 
ATOM   12093 C CA  . ALA D 1 353 ? 41.121  18.367  0.702   1.00 25.70  ? 353 ALA D CA  1 
ATOM   12094 C C   . ALA D 1 353 ? 42.208  18.986  1.564   1.00 27.31  ? 353 ALA D C   1 
ATOM   12095 O O   . ALA D 1 353 ? 43.370  18.584  1.481   1.00 25.18  ? 353 ALA D O   1 
ATOM   12096 C CB  . ALA D 1 353 ? 40.749  19.303  -0.460  1.00 24.53  ? 353 ALA D CB  1 
ATOM   12097 N N   . GLU D 1 354 ? 41.863  19.982  2.393   1.00 25.97  ? 354 GLU D N   1 
ATOM   12098 C CA  . GLU D 1 354 ? 42.929  20.660  3.133   1.00 26.59  ? 354 GLU D CA  1 
ATOM   12099 C C   . GLU D 1 354 ? 43.427  19.817  4.302   1.00 29.36  ? 354 GLU D C   1 
ATOM   12100 O O   . GLU D 1 354 ? 44.587  19.949  4.703   1.00 25.39  ? 354 GLU D O   1 
ATOM   12101 C CB  . GLU D 1 354 ? 42.473  22.035  3.629   1.00 25.26  ? 354 GLU D CB  1 
ATOM   12102 C CG  . GLU D 1 354 ? 41.792  22.034  4.970   1.00 35.79  ? 354 GLU D CG  1 
ATOM   12103 C CD  . GLU D 1 354 ? 41.451  23.445  5.464   1.00 43.82  ? 354 GLU D CD  1 
ATOM   12104 O OE1 . GLU D 1 354 ? 42.151  24.411  5.048   1.00 37.49  ? 354 GLU D OE1 1 
ATOM   12105 O OE2 . GLU D 1 354 ? 40.466  23.567  6.246   1.00 39.10  ? 354 GLU D OE2 1 
ATOM   12106 N N   . ARG D 1 355 ? 42.566  18.971  4.874   1.00 27.74  ? 355 ARG D N   1 
ATOM   12107 C CA  . ARG D 1 355 ? 43.009  18.123  5.973   1.00 29.65  ? 355 ARG D CA  1 
ATOM   12108 C C   . ARG D 1 355 ? 43.896  16.995  5.461   1.00 26.41  ? 355 ARG D C   1 
ATOM   12109 O O   . ARG D 1 355 ? 44.874  16.635  6.119   1.00 27.37  ? 355 ARG D O   1 
ATOM   12110 C CB  . ARG D 1 355 ? 41.809  17.553  6.731   1.00 19.64  ? 355 ARG D CB  1 
ATOM   12111 C CG  . ARG D 1 355 ? 40.955  18.587  7.426   1.00 24.81  ? 355 ARG D CG  1 
ATOM   12112 C CD  . ARG D 1 355 ? 39.808  17.928  8.177   1.00 23.95  ? 355 ARG D CD  1 
ATOM   12113 N NE  . ARG D 1 355 ? 40.308  17.307  9.387   1.00 29.76  ? 355 ARG D NE  1 
ATOM   12114 C CZ  . ARG D 1 355 ? 39.564  16.695  10.291  1.00 28.32  ? 355 ARG D CZ  1 
ATOM   12115 N NH1 . ARG D 1 355 ? 38.251  16.567  10.139  1.00 27.82  ? 355 ARG D NH1 1 
ATOM   12116 N NH2 . ARG D 1 355 ? 40.150  16.207  11.379  1.00 28.39  ? 355 ARG D NH2 1 
ATOM   12117 N N   . LEU D 1 356 ? 43.574  16.436  4.287   1.00 24.71  ? 356 LEU D N   1 
ATOM   12118 C CA  . LEU D 1 356 ? 44.365  15.351  3.716   1.00 29.86  ? 356 LEU D CA  1 
ATOM   12119 C C   . LEU D 1 356 ? 45.599  15.861  2.991   1.00 31.22  ? 356 LEU D C   1 
ATOM   12120 O O   . LEU D 1 356 ? 46.652  15.211  3.014   1.00 29.33  ? 356 LEU D O   1 
ATOM   12121 C CB  . LEU D 1 356 ? 43.524  14.535  2.741   1.00 28.09  ? 356 LEU D CB  1 
ATOM   12122 C CG  . LEU D 1 356 ? 42.442  13.702  3.394   1.00 27.32  ? 356 LEU D CG  1 
ATOM   12123 C CD1 . LEU D 1 356 ? 41.881  12.813  2.332   1.00 26.31  ? 356 LEU D CD1 1 
ATOM   12124 C CD2 . LEU D 1 356 ? 43.045  12.876  4.539   1.00 29.44  ? 356 LEU D CD2 1 
ATOM   12125 N N   . LEU D 1 357 ? 45.478  17.003  2.320   1.00 26.37  ? 357 LEU D N   1 
ATOM   12126 C CA  . LEU D 1 357 ? 46.525  17.476  1.440   1.00 28.57  ? 357 LEU D CA  1 
ATOM   12127 C C   . LEU D 1 357 ? 47.203  18.749  1.906   1.00 32.55  ? 357 LEU D C   1 
ATOM   12128 O O   . LEU D 1 357 ? 48.299  19.045  1.417   1.00 31.43  ? 357 LEU D O   1 
ATOM   12129 C CB  . LEU D 1 357 ? 45.964  17.703  0.033   1.00 26.51  ? 357 LEU D CB  1 
ATOM   12130 C CG  . LEU D 1 357 ? 45.403  16.430  -0.569  1.00 30.04  ? 357 LEU D CG  1 
ATOM   12131 C CD1 . LEU D 1 357 ? 44.907  16.700  -1.966  1.00 33.87  ? 357 LEU D CD1 1 
ATOM   12132 C CD2 . LEU D 1 357 ? 46.482  15.335  -0.551  1.00 25.57  ? 357 LEU D CD2 1 
ATOM   12133 N N   . GLY D 1 358 ? 46.594  19.497  2.829   1.00 27.27  ? 358 GLY D N   1 
ATOM   12134 C CA  . GLY D 1 358 ? 47.183  20.732  3.298   1.00 29.14  ? 358 GLY D CA  1 
ATOM   12135 C C   . GLY D 1 358 ? 46.492  21.963  2.727   1.00 29.78  ? 358 GLY D C   1 
ATOM   12136 O O   . GLY D 1 358 ? 45.870  21.934  1.659   1.00 26.52  ? 358 GLY D O   1 
ATOM   12137 N N   . HIS D 1 359 ? 46.630  23.078  3.456   1.00 29.02  ? 359 HIS D N   1 
ATOM   12138 C CA  . HIS D 1 359 ? 45.952  24.315  3.073   1.00 28.15  ? 359 HIS D CA  1 
ATOM   12139 C C   . HIS D 1 359 ? 46.323  24.745  1.661   1.00 31.56  ? 359 HIS D C   1 
ATOM   12140 O O   . HIS D 1 359 ? 45.548  25.438  0.994   1.00 33.01  ? 359 HIS D O   1 
ATOM   12141 C CB  . HIS D 1 359 ? 46.308  25.430  4.052   1.00 30.55  ? 359 HIS D CB  1 
ATOM   12142 C CG  . HIS D 1 359 ? 47.737  25.858  3.957   1.00 32.89  ? 359 HIS D CG  1 
ATOM   12143 N ND1 . HIS D 1 359 ? 48.188  26.734  2.992   1.00 26.32  ? 359 HIS D ND1 1 
ATOM   12144 C CD2 . HIS D 1 359 ? 48.821  25.516  4.693   1.00 30.34  ? 359 HIS D CD2 1 
ATOM   12145 C CE1 . HIS D 1 359 ? 49.486  26.921  3.143   1.00 30.19  ? 359 HIS D CE1 1 
ATOM   12146 N NE2 . HIS D 1 359 ? 49.894  26.197  4.170   1.00 28.56  ? 359 HIS D NE2 1 
ATOM   12147 N N   . ASP D 1 360 ? 47.491  24.339  1.192   1.00 27.38  ? 360 ASP D N   1 
ATOM   12148 C CA  . ASP D 1 360 ? 48.005  24.737  -0.104  1.00 35.65  ? 360 ASP D CA  1 
ATOM   12149 C C   . ASP D 1 360 ? 47.519  23.864  -1.252  1.00 33.28  ? 360 ASP D C   1 
ATOM   12150 O O   . ASP D 1 360 ? 47.971  24.071  -2.384  1.00 31.24  ? 360 ASP D O   1 
ATOM   12151 C CB  . ASP D 1 360 ? 49.540  24.707  -0.069  1.00 35.41  ? 360 ASP D CB  1 
ATOM   12152 C CG  . ASP D 1 360 ? 50.148  25.795  -0.901  1.00 44.95  ? 360 ASP D CG  1 
ATOM   12153 O OD1 . ASP D 1 360 ? 49.373  26.603  -1.469  1.00 47.96  ? 360 ASP D OD1 1 
ATOM   12154 O OD2 . ASP D 1 360 ? 51.397  25.840  -0.998  1.00 52.19  ? 360 ASP D OD2 1 
ATOM   12155 N N   . TYR D 1 361 ? 46.613  22.905  -0.995  1.00 29.71  ? 361 TYR D N   1 
ATOM   12156 C CA  . TYR D 1 361 ? 46.381  21.809  -1.942  1.00 29.43  ? 361 TYR D CA  1 
ATOM   12157 C C   . TYR D 1 361 ? 46.030  22.293  -3.350  1.00 28.31  ? 361 TYR D C   1 
ATOM   12158 O O   . TYR D 1 361 ? 46.393  21.635  -4.327  1.00 30.53  ? 361 TYR D O   1 
ATOM   12159 C CB  . TYR D 1 361 ? 45.279  20.866  -1.416  1.00 26.12  ? 361 TYR D CB  1 
ATOM   12160 C CG  . TYR D 1 361 ? 43.890  21.467  -1.507  1.00 29.95  ? 361 TYR D CG  1 
ATOM   12161 C CD1 . TYR D 1 361 ? 43.116  21.324  -2.659  1.00 27.94  ? 361 TYR D CD1 1 
ATOM   12162 C CD2 . TYR D 1 361 ? 43.366  22.202  -0.453  1.00 24.36  ? 361 TYR D CD2 1 
ATOM   12163 C CE1 . TYR D 1 361 ? 41.867  21.889  -2.751  1.00 26.34  ? 361 TYR D CE1 1 
ATOM   12164 C CE2 . TYR D 1 361 ? 42.114  22.791  -0.539  1.00 24.89  ? 361 TYR D CE2 1 
ATOM   12165 C CZ  . TYR D 1 361 ? 41.366  22.626  -1.687  1.00 28.04  ? 361 TYR D CZ  1 
ATOM   12166 O OH  . TYR D 1 361 ? 40.116  23.216  -1.782  1.00 26.81  ? 361 TYR D OH  1 
ATOM   12167 N N   . ALA D 1 362 ? 45.336  23.434  -3.485  1.00 31.08  ? 362 ALA D N   1 
ATOM   12168 C CA  . ALA D 1 362 ? 44.845  23.854  -4.802  1.00 31.10  ? 362 ALA D CA  1 
ATOM   12169 C C   . ALA D 1 362 ? 45.966  24.225  -5.765  1.00 35.41  ? 362 ALA D C   1 
ATOM   12170 O O   . ALA D 1 362 ? 45.735  24.281  -6.981  1.00 33.33  ? 362 ALA D O   1 
ATOM   12171 C CB  . ALA D 1 362 ? 43.879  25.031  -4.671  1.00 28.89  ? 362 ALA D CB  1 
ATOM   12172 N N   . ARG D 1 363 ? 47.170  24.479  -5.253  1.00 39.15  ? 363 ARG D N   1 
ATOM   12173 C CA  . ARG D 1 363 ? 48.283  24.839  -6.120  1.00 36.96  ? 363 ARG D CA  1 
ATOM   12174 C C   . ARG D 1 363 ? 48.690  23.674  -7.016  1.00 38.98  ? 363 ARG D C   1 
ATOM   12175 O O   . ARG D 1 363 ? 49.073  23.882  -8.171  1.00 41.88  ? 363 ARG D O   1 
ATOM   12176 C CB  . ARG D 1 363 ? 49.467  25.304  -5.271  1.00 42.67  ? 363 ARG D CB  1 
ATOM   12177 C CG  . ARG D 1 363 ? 50.494  26.134  -6.040  1.00 50.06  ? 363 ARG D CG  1 
ATOM   12178 C CD  . ARG D 1 363 ? 51.532  26.767  -5.117  1.00 48.46  ? 363 ARG D CD  1 
ATOM   12179 N NE  . ARG D 1 363 ? 50.975  27.847  -4.312  1.00 48.92  ? 363 ARG D NE  1 
ATOM   12180 C CZ  . ARG D 1 363 ? 51.109  29.135  -4.602  1.00 55.47  ? 363 ARG D CZ  1 
ATOM   12181 N NH1 . ARG D 1 363 ? 51.764  29.537  -5.682  1.00 46.40  ? 363 ARG D NH1 1 
ATOM   12182 N NH2 . ARG D 1 363 ? 50.577  30.043  -3.786  1.00 58.16  ? 363 ARG D NH2 1 
ATOM   12183 N N   . ASN D 1 364 ? 48.609  22.437  -6.503  1.00 40.12  ? 364 ASN D N   1 
ATOM   12184 C CA  . ASN D 1 364 ? 49.127  21.262  -7.197  1.00 37.49  ? 364 ASN D CA  1 
ATOM   12185 C C   . ASN D 1 364 ? 48.140  20.108  -7.265  1.00 40.50  ? 364 ASN D C   1 
ATOM   12186 O O   . ASN D 1 364 ? 48.528  19.015  -7.700  1.00 37.82  ? 364 ASN D O   1 
ATOM   12187 C CB  . ASN D 1 364 ? 50.400  20.719  -6.525  1.00 39.34  ? 364 ASN D CB  1 
ATOM   12188 C CG  . ASN D 1 364 ? 51.526  21.719  -6.484  1.00 43.85  ? 364 ASN D CG  1 
ATOM   12189 O OD1 . ASN D 1 364 ? 51.892  22.314  -7.496  1.00 50.99  ? 364 ASN D OD1 1 
ATOM   12190 N ND2 . ASN D 1 364 ? 52.105  21.889  -5.308  1.00 44.76  ? 364 ASN D ND2 1 
ATOM   12191 N N   . ASN D 1 365 ? 46.902  20.284  -6.807  1.00 35.25  ? 365 ASN D N   1 
ATOM   12192 C CA  . ASN D 1 365 ? 45.989  19.158  -6.683  1.00 31.70  ? 365 ASN D CA  1 
ATOM   12193 C C   . ASN D 1 365 ? 44.631  19.517  -7.250  1.00 31.37  ? 365 ASN D C   1 
ATOM   12194 O O   . ASN D 1 365 ? 44.241  20.685  -7.286  1.00 37.01  ? 365 ASN D O   1 
ATOM   12195 C CB  . ASN D 1 365 ? 45.823  18.714  -5.234  1.00 32.19  ? 365 ASN D CB  1 
ATOM   12196 C CG  . ASN D 1 365 ? 47.116  18.182  -4.629  1.00 36.11  ? 365 ASN D CG  1 
ATOM   12197 O OD1 . ASN D 1 365 ? 47.407  16.977  -4.687  1.00 27.93  ? 365 ASN D OD1 1 
ATOM   12198 N ND2 . ASN D 1 365 ? 47.892  19.081  -4.029  1.00 38.47  ? 365 ASN D ND2 1 
ATOM   12199 N N   . PHE D 1 366 ? 43.923  18.492  -7.698  1.00 28.43  ? 366 PHE D N   1 
ATOM   12200 C CA  . PHE D 1 366 ? 42.559  18.592  -8.168  1.00 28.21  ? 366 PHE D CA  1 
ATOM   12201 C C   . PHE D 1 366 ? 41.689  17.621  -7.387  1.00 26.53  ? 366 PHE D C   1 
ATOM   12202 O O   . PHE D 1 366 ? 42.180  16.641  -6.816  1.00 27.22  ? 366 PHE D O   1 
ATOM   12203 C CB  . PHE D 1 366 ? 42.467  18.278  -9.665  1.00 28.27  ? 366 PHE D CB  1 
ATOM   12204 C CG  . PHE D 1 366 ? 43.354  19.130  -10.506 1.00 34.41  ? 366 PHE D CG  1 
ATOM   12205 C CD1 . PHE D 1 366 ? 44.669  18.747  -10.767 1.00 35.32  ? 366 PHE D CD1 1 
ATOM   12206 C CD2 . PHE D 1 366 ? 42.884  20.318  -11.040 1.00 33.52  ? 366 PHE D CD2 1 
ATOM   12207 C CE1 . PHE D 1 366 ? 45.495  19.538  -11.552 1.00 35.59  ? 366 PHE D CE1 1 
ATOM   12208 C CE2 . PHE D 1 366 ? 43.712  21.125  -11.819 1.00 36.63  ? 366 PHE D CE2 1 
ATOM   12209 C CZ  . PHE D 1 366 ? 45.012  20.732  -12.074 1.00 38.21  ? 366 PHE D CZ  1 
ATOM   12210 N N   . PHE D 1 367 ? 40.386  17.897  -7.355  1.00 24.53  ? 367 PHE D N   1 
ATOM   12211 C CA  . PHE D 1 367 ? 39.455  16.871  -6.916  1.00 28.75  ? 367 PHE D CA  1 
ATOM   12212 C C   . PHE D 1 367 ? 38.134  16.998  -7.660  1.00 32.32  ? 367 PHE D C   1 
ATOM   12213 O O   . PHE D 1 367 ? 37.863  17.970  -8.368  1.00 32.23  ? 367 PHE D O   1 
ATOM   12214 C CB  . PHE D 1 367 ? 39.259  16.860  -5.389  1.00 28.38  ? 367 PHE D CB  1 
ATOM   12215 C CG  . PHE D 1 367 ? 38.584  18.077  -4.799  1.00 28.69  ? 367 PHE D CG  1 
ATOM   12216 C CD1 . PHE D 1 367 ? 37.207  18.224  -4.844  1.00 31.12  ? 367 PHE D CD1 1 
ATOM   12217 C CD2 . PHE D 1 367 ? 39.322  19.013  -4.092  1.00 28.48  ? 367 PHE D CD2 1 
ATOM   12218 C CE1 . PHE D 1 367 ? 36.582  19.313  -4.243  1.00 31.74  ? 367 PHE D CE1 1 
ATOM   12219 C CE2 . PHE D 1 367 ? 38.701  20.105  -3.494  1.00 30.38  ? 367 PHE D CE2 1 
ATOM   12220 C CZ  . PHE D 1 367 ? 37.327  20.245  -3.555  1.00 28.42  ? 367 PHE D CZ  1 
ATOM   12221 N N   . SER D 1 368 ? 37.319  15.973  -7.490  1.00 31.99  ? 368 SER D N   1 
ATOM   12222 C CA  . SER D 1 368 ? 36.106  15.825  -8.267  1.00 34.07  ? 368 SER D CA  1 
ATOM   12223 C C   . SER D 1 368 ? 35.267  14.793  -7.547  1.00 25.07  ? 368 SER D C   1 
ATOM   12224 O O   . SER D 1 368 ? 35.799  13.790  -7.069  1.00 29.34  ? 368 SER D O   1 
ATOM   12225 C CB  . SER D 1 368 ? 36.417  15.379  -9.703  1.00 30.75  ? 368 SER D CB  1 
ATOM   12226 O OG  . SER D 1 368 ? 35.276  15.471  -10.526 1.00 30.50  ? 368 SER D OG  1 
ATOM   12227 N N   . SER D 1 369 ? 33.972  15.045  -7.457  1.00 27.42  ? 369 SER D N   1 
ATOM   12228 C CA  . SER D 1 369 ? 33.071  14.137  -6.775  1.00 28.85  ? 369 SER D CA  1 
ATOM   12229 C C   . SER D 1 369 ? 32.213  13.386  -7.785  1.00 31.44  ? 369 SER D C   1 
ATOM   12230 O O   . SER D 1 369 ? 31.942  13.867  -8.890  1.00 36.06  ? 369 SER D O   1 
ATOM   12231 C CB  . SER D 1 369 ? 32.182  14.888  -5.776  1.00 31.12  ? 369 SER D CB  1 
ATOM   12232 O OG  . SER D 1 369 ? 31.330  15.795  -6.443  1.00 32.51  ? 369 SER D OG  1 
ATOM   12233 N N   . ILE D 1 370 ? 31.814  12.187  -7.397  1.00 31.23  ? 370 ILE D N   1 
ATOM   12234 C CA  . ILE D 1 370 ? 30.795  11.415  -8.086  1.00 33.17  ? 370 ILE D CA  1 
ATOM   12235 C C   . ILE D 1 370 ? 29.635  11.269  -7.121  1.00 31.92  ? 370 ILE D C   1 
ATOM   12236 O O   . ILE D 1 370 ? 29.808  10.745  -6.014  1.00 29.46  ? 370 ILE D O   1 
ATOM   12237 C CB  . ILE D 1 370 ? 31.299  10.026  -8.511  1.00 34.89  ? 370 ILE D CB  1 
ATOM   12238 C CG1 . ILE D 1 370 ? 32.721  10.086  -9.045  1.00 33.10  ? 370 ILE D CG1 1 
ATOM   12239 C CG2 . ILE D 1 370 ? 30.314  9.343   -9.471  1.00 35.11  ? 370 ILE D CG2 1 
ATOM   12240 C CD1 . ILE D 1 370 ? 33.414  8.724   -8.981  1.00 35.32  ? 370 ILE D CD1 1 
ATOM   12241 N N   . LEU D 1 371 ? 28.459  11.710  -7.539  1.00 37.11  ? 371 LEU D N   1 
ATOM   12242 C CA  . LEU D 1 371 ? 27.250  11.395  -6.797  1.00 43.75  ? 371 LEU D CA  1 
ATOM   12243 C C   . LEU D 1 371 ? 26.543  10.143  -7.319  1.00 43.70  ? 371 LEU D C   1 
ATOM   12244 O O   . LEU D 1 371 ? 25.647  9.636   -6.637  1.00 43.14  ? 371 LEU D O   1 
ATOM   12245 C CB  . LEU D 1 371 ? 26.306  12.607  -6.806  1.00 43.16  ? 371 LEU D CB  1 
ATOM   12246 C CG  . LEU D 1 371 ? 26.980  13.985  -6.675  1.00 46.40  ? 371 LEU D CG  1 
ATOM   12247 C CD1 . LEU D 1 371 ? 26.029  15.126  -7.069  1.00 45.62  ? 371 LEU D CD1 1 
ATOM   12248 C CD2 . LEU D 1 371 ? 27.544  14.203  -5.257  1.00 42.15  ? 371 LEU D CD2 1 
ATOM   12249 N N   . ASN D 1 372 ? 26.991  9.593   -8.458  1.00 47.31  ? 372 ASN D N   1 
ATOM   12250 C CA  . ASN D 1 372 ? 26.291  8.601   -9.274  1.00 47.53  ? 372 ASN D CA  1 
ATOM   12251 C C   . ASN D 1 372 ? 26.529  7.146   -8.876  1.00 46.73  ? 372 ASN D C   1 
ATOM   12252 O O   . ASN D 1 372 ? 25.826  6.271   -9.393  1.00 42.20  ? 372 ASN D O   1 
ATOM   12253 C CB  . ASN D 1 372 ? 26.720  8.721   -10.748 1.00 48.07  ? 372 ASN D CB  1 
ATOM   12254 C CG  . ASN D 1 372 ? 26.412  10.062  -11.346 1.00 51.97  ? 372 ASN D CG  1 
ATOM   12255 O OD1 . ASN D 1 372 ? 26.846  11.102  -10.839 1.00 55.90  ? 372 ASN D OD1 1 
ATOM   12256 N ND2 . ASN D 1 372 ? 25.644  10.056  -12.431 1.00 56.73  ? 372 ASN D ND2 1 
ATOM   12257 N N   . VAL D 1 373 ? 27.523  6.856   -8.030  1.00 45.59  ? 373 VAL D N   1 
ATOM   12258 C CA  . VAL D 1 373 ? 27.941  5.474   -7.800  1.00 41.88  ? 373 VAL D CA  1 
ATOM   12259 C C   . VAL D 1 373 ? 26.767  4.627   -7.332  1.00 38.10  ? 373 VAL D C   1 
ATOM   12260 O O   . VAL D 1 373 ? 25.931  5.082   -6.541  1.00 40.36  ? 373 VAL D O   1 
ATOM   12261 C CB  . VAL D 1 373 ? 29.084  5.443   -6.772  1.00 41.60  ? 373 VAL D CB  1 
ATOM   12262 C CG1 . VAL D 1 373 ? 29.394  4.010   -6.358  1.00 39.07  ? 373 VAL D CG1 1 
ATOM   12263 C CG2 . VAL D 1 373 ? 30.328  6.137   -7.327  1.00 37.20  ? 373 VAL D CG2 1 
ATOM   12264 N N   . VAL D 1 374 ? 26.692  3.390   -7.820  1.00 33.12  ? 374 VAL D N   1 
ATOM   12265 C CA  . VAL D 1 374 ? 25.660  2.479   -7.297  1.00 39.10  ? 374 VAL D CA  1 
ATOM   12266 C C   . VAL D 1 374 ? 25.819  2.358   -5.786  1.00 33.06  ? 374 VAL D C   1 
ATOM   12267 O O   . VAL D 1 374 ? 26.950  2.211   -5.295  1.00 36.91  ? 374 VAL D O   1 
ATOM   12268 C CB  . VAL D 1 374 ? 25.749  1.087   -7.964  1.00 37.43  ? 374 VAL D CB  1 
ATOM   12269 C CG1 . VAL D 1 374 ? 25.063  0.053   -7.093  1.00 33.81  ? 374 VAL D CG1 1 
ATOM   12270 C CG2 . VAL D 1 374 ? 25.095  1.090   -9.326  1.00 35.34  ? 374 VAL D CG2 1 
ATOM   12271 N N   . PRO D 1 375 ? 24.749  2.450   -5.006  1.00 33.63  ? 375 PRO D N   1 
ATOM   12272 C CA  . PRO D 1 375 ? 24.882  2.303   -3.551  1.00 38.18  ? 375 PRO D CA  1 
ATOM   12273 C C   . PRO D 1 375 ? 25.373  0.918   -3.153  1.00 36.67  ? 375 PRO D C   1 
ATOM   12274 O O   . PRO D 1 375 ? 25.011  -0.093  -3.762  1.00 32.71  ? 375 PRO D O   1 
ATOM   12275 C CB  . PRO D 1 375 ? 23.461  2.560   -3.037  1.00 39.15  ? 375 PRO D CB  1 
ATOM   12276 C CG  . PRO D 1 375 ? 22.814  3.414   -4.113  1.00 41.86  ? 375 PRO D CG  1 
ATOM   12277 C CD  . PRO D 1 375 ? 23.429  2.972   -5.408  1.00 38.82  ? 375 PRO D CD  1 
ATOM   12278 N N   . ALA D 1 376 ? 26.216  0.890   -2.122  1.00 36.64  ? 376 ALA D N   1 
ATOM   12279 C CA  . ALA D 1 376 ? 26.677  -0.351  -1.512  1.00 34.57  ? 376 ALA D CA  1 
ATOM   12280 C C   . ALA D 1 376 ? 27.148  -0.037  -0.100  1.00 35.59  ? 376 ALA D C   1 
ATOM   12281 O O   . ALA D 1 376 ? 27.430  1.117   0.234   1.00 34.30  ? 376 ALA D O   1 
ATOM   12282 C CB  . ALA D 1 376 ? 27.794  -1.004  -2.324  1.00 29.15  ? 376 ALA D CB  1 
ATOM   12283 N N   . GLY D 1 377 ? 27.204  -1.066  0.735   1.00 28.23  ? 377 GLY D N   1 
ATOM   12284 C CA  . GLY D 1 377 ? 27.737  -0.884  2.068   1.00 33.31  ? 377 GLY D CA  1 
ATOM   12285 C C   . GLY D 1 377 ? 29.171  -0.381  2.015   1.00 34.22  ? 377 GLY D C   1 
ATOM   12286 O O   . GLY D 1 377 ? 29.842  -0.405  0.985   1.00 32.80  ? 377 GLY D O   1 
ATOM   12287 N N   . LEU D 1 378 ? 29.644  0.103   3.162   1.00 41.24  ? 378 LEU D N   1 
ATOM   12288 C CA  . LEU D 1 378 ? 30.989  0.666   3.226   1.00 34.82  ? 378 LEU D CA  1 
ATOM   12289 C C   . LEU D 1 378 ? 32.039  -0.344  2.762   1.00 34.11  ? 378 LEU D C   1 
ATOM   12290 O O   . LEU D 1 378 ? 32.899  -0.025  1.928   1.00 30.23  ? 378 LEU D O   1 
ATOM   12291 C CB  . LEU D 1 378 ? 31.290  1.131   4.648   1.00 32.15  ? 378 LEU D CB  1 
ATOM   12292 C CG  . LEU D 1 378 ? 32.682  1.758   4.725   1.00 32.96  ? 378 LEU D CG  1 
ATOM   12293 C CD1 . LEU D 1 378 ? 32.832  2.825   3.643   1.00 22.16  ? 378 LEU D CD1 1 
ATOM   12294 C CD2 . LEU D 1 378 ? 32.975  2.301   6.125   1.00 32.75  ? 378 LEU D CD2 1 
ATOM   12295 N N   . ALA D 1 379 ? 31.974  -1.569  3.296   1.00 29.65  ? 379 ALA D N   1 
ATOM   12296 C CA  . ALA D 1 379 ? 32.963  -2.599  2.986   1.00 32.27  ? 379 ALA D CA  1 
ATOM   12297 C C   . ALA D 1 379 ? 33.034  -2.861  1.492   1.00 29.06  ? 379 ALA D C   1 
ATOM   12298 O O   . ALA D 1 379 ? 34.121  -2.914  0.911   1.00 28.53  ? 379 ALA D O   1 
ATOM   12299 C CB  . ALA D 1 379 ? 32.625  -3.891  3.732   1.00 28.75  ? 379 ALA D CB  1 
ATOM   12300 N N   . ASP D 1 380 ? 31.874  -3.019  0.851   1.00 31.46  ? 380 ASP D N   1 
ATOM   12301 C CA  . ASP D 1 380 ? 31.852  -3.281  -0.582  1.00 30.60  ? 380 ASP D CA  1 
ATOM   12302 C C   . ASP D 1 380 ? 32.357  -2.078  -1.369  1.00 32.25  ? 380 ASP D C   1 
ATOM   12303 O O   . ASP D 1 380 ? 33.098  -2.238  -2.351  1.00 30.94  ? 380 ASP D O   1 
ATOM   12304 C CB  . ASP D 1 380 ? 30.439  -3.670  -1.014  1.00 34.96  ? 380 ASP D CB  1 
ATOM   12305 C CG  . ASP D 1 380 ? 29.980  -4.977  -0.396  1.00 34.60  ? 380 ASP D CG  1 
ATOM   12306 O OD1 . ASP D 1 380 ? 30.840  -5.814  -0.051  1.00 36.91  ? 380 ASP D OD1 1 
ATOM   12307 O OD2 . ASP D 1 380 ? 28.757  -5.177  -0.256  1.00 43.16  ? 380 ASP D OD2 1 
ATOM   12308 N N   . LEU D 1 381 ? 31.969  -0.865  -0.952  1.00 28.73  ? 381 LEU D N   1 
ATOM   12309 C CA  . LEU D 1 381 ? 32.469  0.343   -1.604  1.00 31.32  ? 381 LEU D CA  1 
ATOM   12310 C C   . LEU D 1 381 ? 33.988  0.418   -1.515  1.00 27.68  ? 381 LEU D C   1 
ATOM   12311 O O   . LEU D 1 381 ? 34.669  0.577   -2.536  1.00 28.11  ? 381 LEU D O   1 
ATOM   12312 C CB  . LEU D 1 381 ? 31.833  1.600   -0.986  1.00 33.93  ? 381 LEU D CB  1 
ATOM   12313 C CG  . LEU D 1 381 ? 30.506  2.150   -1.541  1.00 35.14  ? 381 LEU D CG  1 
ATOM   12314 C CD1 . LEU D 1 381 ? 30.163  3.510   -0.914  1.00 32.58  ? 381 LEU D CD1 1 
ATOM   12315 C CD2 . LEU D 1 381 ? 30.515  2.258   -3.051  1.00 35.87  ? 381 LEU D CD2 1 
ATOM   12316 N N   . LEU D 1 382 ? 34.542  0.299   -0.299  1.00 24.34  ? 382 LEU D N   1 
ATOM   12317 C CA  . LEU D 1 382 ? 35.999  0.305   -0.161  1.00 25.81  ? 382 LEU D CA  1 
ATOM   12318 C C   . LEU D 1 382 ? 36.645  -0.824  -0.966  1.00 31.16  ? 382 LEU D C   1 
ATOM   12319 O O   . LEU D 1 382 ? 37.701  -0.630  -1.583  1.00 29.32  ? 382 LEU D O   1 
ATOM   12320 C CB  . LEU D 1 382 ? 36.402  0.199   1.307   1.00 24.42  ? 382 LEU D CB  1 
ATOM   12321 C CG  . LEU D 1 382 ? 36.099  1.466   2.116   1.00 30.90  ? 382 LEU D CG  1 
ATOM   12322 C CD1 . LEU D 1 382 ? 36.776  1.426   3.484   1.00 27.67  ? 382 LEU D CD1 1 
ATOM   12323 C CD2 . LEU D 1 382 ? 36.490  2.725   1.335   1.00 20.79  ? 382 LEU D CD2 1 
ATOM   12324 N N   . ARG D 1 383 ? 36.020  -2.008  -0.982  1.00 28.19  ? 383 ARG D N   1 
ATOM   12325 C CA  . ARG D 1 383 ? 36.583  -3.119  -1.749  1.00 29.17  ? 383 ARG D CA  1 
ATOM   12326 C C   . ARG D 1 383 ? 36.580  -2.822  -3.244  1.00 27.78  ? 383 ARG D C   1 
ATOM   12327 O O   . ARG D 1 383 ? 37.497  -3.236  -3.953  1.00 30.98  ? 383 ARG D O   1 
ATOM   12328 C CB  . ARG D 1 383 ? 35.821  -4.415  -1.450  1.00 26.18  ? 383 ARG D CB  1 
ATOM   12329 C CG  . ARG D 1 383 ? 36.294  -5.610  -2.287  1.00 28.88  ? 383 ARG D CG  1 
ATOM   12330 C CD  . ARG D 1 383 ? 37.254  -6.503  -1.517  1.00 41.01  ? 383 ARG D CD  1 
ATOM   12331 N NE  . ARG D 1 383 ? 38.617  -5.980  -1.472  1.00 37.14  ? 383 ARG D NE  1 
ATOM   12332 C CZ  . ARG D 1 383 ? 39.508  -6.038  -2.456  1.00 34.06  ? 383 ARG D CZ  1 
ATOM   12333 N NH1 . ARG D 1 383 ? 39.226  -6.603  -3.619  1.00 33.10  ? 383 ARG D NH1 1 
ATOM   12334 N NH2 . ARG D 1 383 ? 40.723  -5.531  -2.261  1.00 32.38  ? 383 ARG D NH2 1 
ATOM   12335 N N   . SER D 1 384 ? 35.572  -2.094  -3.738  1.00 29.18  ? 384 SER D N   1 
ATOM   12336 C CA  . SER D 1 384 ? 35.548  -1.699  -5.146  1.00 27.62  ? 384 SER D CA  1 
ATOM   12337 C C   . SER D 1 384 ? 36.647  -0.691  -5.460  1.00 30.31  ? 384 SER D C   1 
ATOM   12338 O O   . SER D 1 384 ? 37.293  -0.776  -6.511  1.00 33.68  ? 384 SER D O   1 
ATOM   12339 C CB  . SER D 1 384 ? 34.179  -1.104  -5.506  1.00 33.52  ? 384 SER D CB  1 
ATOM   12340 O OG  . SER D 1 384 ? 33.142  -2.069  -5.429  1.00 34.50  ? 384 SER D OG  1 
ATOM   12341 N N   . LEU D 1 385 ? 36.865  0.276   -4.563  1.00 24.40  ? 385 LEU D N   1 
ATOM   12342 C CA  . LEU D 1 385 ? 37.966  1.222   -4.731  1.00 26.05  ? 385 LEU D CA  1 
ATOM   12343 C C   . LEU D 1 385 ? 39.307  0.506   -4.832  1.00 27.50  ? 385 LEU D C   1 
ATOM   12344 O O   . LEU D 1 385 ? 40.150  0.855   -5.668  1.00 30.99  ? 385 LEU D O   1 
ATOM   12345 C CB  . LEU D 1 385 ? 37.991  2.205   -3.569  1.00 23.36  ? 385 LEU D CB  1 
ATOM   12346 C CG  . LEU D 1 385 ? 36.757  3.112   -3.442  1.00 31.20  ? 385 LEU D CG  1 
ATOM   12347 C CD1 . LEU D 1 385 ? 36.923  4.099   -2.258  1.00 24.45  ? 385 LEU D CD1 1 
ATOM   12348 C CD2 . LEU D 1 385 ? 36.535  3.835   -4.772  1.00 22.62  ? 385 LEU D CD2 1 
ATOM   12349 N N   . GLU D 1 386 ? 39.536  -0.475  -3.959  1.00 24.85  ? 386 GLU D N   1 
ATOM   12350 C CA  . GLU D 1 386 ? 40.771  -1.253  -4.030  1.00 29.59  ? 386 GLU D CA  1 
ATOM   12351 C C   . GLU D 1 386 ? 40.831  -2.071  -5.325  1.00 29.97  ? 386 GLU D C   1 
ATOM   12352 O O   . GLU D 1 386 ? 41.868  -2.110  -5.994  1.00 28.52  ? 386 GLU D O   1 
ATOM   12353 C CB  . GLU D 1 386 ? 40.885  -2.152  -2.799  1.00 27.69  ? 386 GLU D CB  1 
ATOM   12354 C CG  . GLU D 1 386 ? 41.021  -1.391  -1.453  1.00 31.37  ? 386 GLU D CG  1 
ATOM   12355 C CD  . GLU D 1 386 ? 41.211  -2.331  -0.250  1.00 32.98  ? 386 GLU D CD  1 
ATOM   12356 O OE1 . GLU D 1 386 ? 41.868  -3.386  -0.419  1.00 30.82  ? 386 GLU D OE1 1 
ATOM   12357 O OE2 . GLU D 1 386 ? 40.704  -2.019  0.864   1.00 31.19  ? 386 GLU D OE2 1 
ATOM   12358 N N   . ARG D 1 387 ? 39.715  -2.698  -5.712  1.00 31.87  ? 387 ARG D N   1 
ATOM   12359 C CA  . ARG D 1 387 ? 39.661  -3.414  -6.987  1.00 33.03  ? 387 ARG D CA  1 
ATOM   12360 C C   . ARG D 1 387 ? 40.079  -2.534  -8.158  1.00 31.25  ? 387 ARG D C   1 
ATOM   12361 O O   . ARG D 1 387 ? 40.830  -2.976  -9.030  1.00 30.64  ? 387 ARG D O   1 
ATOM   12362 C CB  . ARG D 1 387 ? 38.259  -3.960  -7.220  1.00 30.83  ? 387 ARG D CB  1 
ATOM   12363 C CG  . ARG D 1 387 ? 38.165  -4.927  -8.393  1.00 41.76  ? 387 ARG D CG  1 
ATOM   12364 C CD  . ARG D 1 387 ? 36.912  -5.796  -8.299  1.00 29.42  ? 387 ARG D CD  1 
ATOM   12365 N NE  . ARG D 1 387 ? 35.685  -5.027  -8.394  1.00 38.25  ? 387 ARG D NE  1 
ATOM   12366 C CZ  . ARG D 1 387 ? 34.853  -4.824  -7.383  1.00 38.40  ? 387 ARG D CZ  1 
ATOM   12367 N NH1 . ARG D 1 387 ? 35.093  -5.324  -6.177  1.00 34.04  ? 387 ARG D NH1 1 
ATOM   12368 N NH2 . ARG D 1 387 ? 33.752  -4.105  -7.587  1.00 33.85  ? 387 ARG D NH2 1 
ATOM   12369 N N   . ALA D 1 388 ? 39.606  -1.282  -8.199  1.00 32.04  ? 388 ALA D N   1 
ATOM   12370 C CA  . ALA D 1 388 ? 40.023  -0.381  -9.268  1.00 34.65  ? 388 ALA D CA  1 
ATOM   12371 C C   . ALA D 1 388 ? 41.408  0.196   -9.048  1.00 32.98  ? 388 ALA D C   1 
ATOM   12372 O O   . ALA D 1 388 ? 41.949  0.821   -9.964  1.00 38.74  ? 388 ALA D O   1 
ATOM   12373 C CB  . ALA D 1 388 ? 39.028  0.769   -9.435  1.00 36.02  ? 388 ALA D CB  1 
ATOM   12374 N N   . GLY D 1 389 ? 41.980  0.023   -7.863  1.00 33.24  ? 389 GLY D N   1 
ATOM   12375 C CA  . GLY D 1 389 ? 43.299  0.546   -7.573  1.00 29.60  ? 389 GLY D CA  1 
ATOM   12376 C C   . GLY D 1 389 ? 43.346  2.037   -7.328  1.00 33.77  ? 389 GLY D C   1 
ATOM   12377 O O   . GLY D 1 389 ? 44.314  2.694   -7.728  1.00 35.49  ? 389 GLY D O   1 
ATOM   12378 N N   . VAL D 1 390 ? 42.325  2.602   -6.676  1.00 35.30  ? 390 VAL D N   1 
ATOM   12379 C CA  . VAL D 1 390 ? 42.284  4.045   -6.431  1.00 33.85  ? 390 VAL D CA  1 
ATOM   12380 C C   . VAL D 1 390 ? 41.747  4.378   -5.040  1.00 32.41  ? 390 VAL D C   1 
ATOM   12381 O O   . VAL D 1 390 ? 41.309  5.506   -4.799  1.00 36.14  ? 390 VAL D O   1 
ATOM   12382 C CB  . VAL D 1 390 ? 41.433  4.769   -7.498  1.00 32.79  ? 390 VAL D CB  1 
ATOM   12383 C CG1 . VAL D 1 390 ? 41.920  4.469   -8.903  1.00 29.91  ? 390 VAL D CG1 1 
ATOM   12384 C CG2 . VAL D 1 390 ? 39.979  4.395   -7.353  1.00 28.28  ? 390 VAL D CG2 1 
ATOM   12385 N N   . ARG D 1 391 ? 41.767  3.432   -4.106  1.00 27.65  ? 391 ARG D N   1 
ATOM   12386 C CA  . ARG D 1 391 ? 41.447  3.809   -2.733  1.00 33.55  ? 391 ARG D CA  1 
ATOM   12387 C C   . ARG D 1 391 ? 42.458  4.835   -2.237  1.00 31.30  ? 391 ARG D C   1 
ATOM   12388 O O   . ARG D 1 391 ? 43.661  4.703   -2.484  1.00 29.53  ? 391 ARG D O   1 
ATOM   12389 C CB  . ARG D 1 391 ? 41.433  2.595   -1.800  1.00 27.66  ? 391 ARG D CB  1 
ATOM   12390 C CG  . ARG D 1 391 ? 41.055  2.986   -0.382  1.00 31.54  ? 391 ARG D CG  1 
ATOM   12391 C CD  . ARG D 1 391 ? 41.045  1.804   0.611   1.00 30.51  ? 391 ARG D CD  1 
ATOM   12392 N NE  . ARG D 1 391 ? 40.784  2.259   1.976   1.00 21.60  ? 391 ARG D NE  1 
ATOM   12393 C CZ  . ARG D 1 391 ? 40.390  1.467   2.961   1.00 29.42  ? 391 ARG D CZ  1 
ATOM   12394 N NH1 . ARG D 1 391 ? 40.245  0.162   2.787   1.00 31.84  ? 391 ARG D NH1 1 
ATOM   12395 N NH2 . ARG D 1 391 ? 40.143  1.993   4.153   1.00 28.86  ? 391 ARG D NH2 1 
ATOM   12396 N N   . TYR D 1 392 ? 41.963  5.877   -1.555  1.00 29.85  ? 392 TYR D N   1 
ATOM   12397 C CA  . TYR D 1 392 ? 42.838  6.969   -1.151  1.00 28.41  ? 392 TYR D CA  1 
ATOM   12398 C C   . TYR D 1 392 ? 44.068  6.434   -0.432  1.00 28.40  ? 392 TYR D C   1 
ATOM   12399 O O   . TYR D 1 392 ? 43.971  5.536   0.408   1.00 25.55  ? 392 TYR D O   1 
ATOM   12400 C CB  . TYR D 1 392 ? 42.135  7.967   -0.232  1.00 29.56  ? 392 TYR D CB  1 
ATOM   12401 C CG  . TYR D 1 392 ? 43.065  9.122   0.066   1.00 27.16  ? 392 TYR D CG  1 
ATOM   12402 C CD1 . TYR D 1 392 ? 43.351  10.072  -0.916  1.00 29.43  ? 392 TYR D CD1 1 
ATOM   12403 C CD2 . TYR D 1 392 ? 43.714  9.224   1.281   1.00 28.57  ? 392 TYR D CD2 1 
ATOM   12404 C CE1 . TYR D 1 392 ? 44.218  11.119  -0.674  1.00 29.11  ? 392 TYR D CE1 1 
ATOM   12405 C CE2 . TYR D 1 392 ? 44.585  10.267  1.538   1.00 29.22  ? 392 TYR D CE2 1 
ATOM   12406 C CZ  . TYR D 1 392 ? 44.838  11.203  0.554   1.00 28.48  ? 392 TYR D CZ  1 
ATOM   12407 O OH  . TYR D 1 392 ? 45.699  12.231  0.801   1.00 24.90  ? 392 TYR D OH  1 
ATOM   12408 N N   . ASP D 1 393 ? 45.214  7.047   -0.727  1.00 27.34  ? 393 ASP D N   1 
ATOM   12409 C CA  . ASP D 1 393 ? 46.530  6.512   -0.384  1.00 33.50  ? 393 ASP D CA  1 
ATOM   12410 C C   . ASP D 1 393 ? 47.323  7.650   0.246   1.00 27.53  ? 393 ASP D C   1 
ATOM   12411 O O   . ASP D 1 393 ? 47.798  8.535   -0.466  1.00 32.12  ? 393 ASP D O   1 
ATOM   12412 C CB  . ASP D 1 393 ? 47.221  5.965   -1.640  1.00 30.89  ? 393 ASP D CB  1 
ATOM   12413 C CG  . ASP D 1 393 ? 48.609  5.424   -1.371  1.00 38.68  ? 393 ASP D CG  1 
ATOM   12414 O OD1 . ASP D 1 393 ? 49.462  6.179   -0.876  1.00 38.15  ? 393 ASP D OD1 1 
ATOM   12415 O OD2 . ASP D 1 393 ? 48.858  4.239   -1.689  1.00 45.08  ? 393 ASP D OD2 1 
ATOM   12416 N N   . LYS D 1 394 ? 47.475  7.635   1.573   1.00 33.80  ? 394 LYS D N   1 
ATOM   12417 C CA  . LYS D 1 394 ? 48.210  8.718   2.225   1.00 36.55  ? 394 LYS D CA  1 
ATOM   12418 C C   . LYS D 1 394 ? 49.666  8.829   1.757   1.00 36.70  ? 394 LYS D C   1 
ATOM   12419 O O   . LYS D 1 394 ? 50.291  9.859   2.013   1.00 42.31  ? 394 LYS D O   1 
ATOM   12420 C CB  . LYS D 1 394 ? 48.176  8.555   3.750   1.00 38.55  ? 394 LYS D CB  1 
ATOM   12421 C CG  . LYS D 1 394 ? 48.695  7.219   4.247   1.00 41.33  ? 394 LYS D CG  1 
ATOM   12422 C CD  . LYS D 1 394 ? 49.513  7.357   5.510   1.00 41.62  ? 394 LYS D CD  1 
ATOM   12423 C CE  . LYS D 1 394 ? 50.038  6.002   5.954   1.00 50.99  ? 394 LYS D CE  1 
ATOM   12424 N NZ  . LYS D 1 394 ? 51.478  5.805   5.611   1.00 53.68  ? 394 LYS D NZ  1 
ATOM   12425 N N   . ASP D 1 395 ? 50.218  7.826   1.066   1.00 32.99  ? 395 ASP D N   1 
ATOM   12426 C CA  . ASP D 1 395 ? 51.606  7.939   0.608   1.00 40.37  ? 395 ASP D CA  1 
ATOM   12427 C C   . ASP D 1 395 ? 51.728  8.812   -0.631  1.00 37.54  ? 395 ASP D C   1 
ATOM   12428 O O   . ASP D 1 395 ? 52.722  9.528   -0.793  1.00 38.52  ? 395 ASP D O   1 
ATOM   12429 C CB  . ASP D 1 395 ? 52.203  6.558   0.318   1.00 37.55  ? 395 ASP D CB  1 
ATOM   12430 C CG  . ASP D 1 395 ? 52.430  5.748   1.573   1.00 40.57  ? 395 ASP D CG  1 
ATOM   12431 O OD1 . ASP D 1 395 ? 52.832  6.349   2.595   1.00 42.25  ? 395 ASP D OD1 1 
ATOM   12432 O OD2 . ASP D 1 395 ? 52.209  4.512   1.530   1.00 47.58  ? 395 ASP D OD2 1 
ATOM   12433 N N   . SER D 1 396 ? 50.750  8.742   -1.528  1.00 33.67  ? 396 SER D N   1 
ATOM   12434 C CA  . SER D 1 396 ? 50.731  9.586   -2.711  1.00 32.26  ? 396 SER D CA  1 
ATOM   12435 C C   . SER D 1 396 ? 49.779  10.761  -2.580  1.00 34.30  ? 396 SER D C   1 
ATOM   12436 O O   . SER D 1 396 ? 49.917  11.735  -3.323  1.00 35.85  ? 396 SER D O   1 
ATOM   12437 C CB  . SER D 1 396 ? 50.324  8.769   -3.949  1.00 33.58  ? 396 SER D CB  1 
ATOM   12438 O OG  . SER D 1 396 ? 48.976  8.329   -3.833  1.00 30.31  ? 396 SER D OG  1 
ATOM   12439 N N   . GLY D 1 397 ? 48.817  10.688  -1.665  1.00 35.77  ? 397 GLY D N   1 
ATOM   12440 C CA  . GLY D 1 397 ? 47.794  11.713  -1.596  1.00 33.10  ? 397 GLY D CA  1 
ATOM   12441 C C   . GLY D 1 397 ? 46.878  11.688  -2.790  1.00 33.39  ? 397 GLY D C   1 
ATOM   12442 O O   . GLY D 1 397 ? 46.365  12.737  -3.192  1.00 37.06  ? 397 GLY D O   1 
ATOM   12443 N N   . GLU D 1 398 ? 46.667  10.507  -3.376  1.00 31.20  ? 398 GLU D N   1 
ATOM   12444 C CA  . GLU D 1 398 ? 45.813  10.322  -4.534  1.00 31.20  ? 398 GLU D CA  1 
ATOM   12445 C C   . GLU D 1 398 ? 44.813  9.207   -4.258  1.00 32.02  ? 398 GLU D C   1 
ATOM   12446 O O   . GLU D 1 398 ? 45.090  8.262   -3.507  1.00 30.22  ? 398 GLU D O   1 
ATOM   12447 C CB  . GLU D 1 398 ? 46.627  9.988   -5.806  1.00 31.37  ? 398 GLU D CB  1 
ATOM   12448 C CG  . GLU D 1 398 ? 47.622  11.055  -6.229  1.00 36.55  ? 398 GLU D CG  1 
ATOM   12449 C CD  . GLU D 1 398 ? 47.790  11.158  -7.751  1.00 39.94  ? 398 GLU D CD  1 
ATOM   12450 O OE1 . GLU D 1 398 ? 47.251  10.290  -8.474  1.00 43.23  ? 398 GLU D OE1 1 
ATOM   12451 O OE2 . GLU D 1 398 ? 48.468  12.106  -8.222  1.00 33.10  ? 398 GLU D OE2 1 
ATOM   12452 N N   . GLY D 1 399 ? 43.651  9.312   -4.885  1.00 27.10  ? 399 GLY D N   1 
ATOM   12453 C CA  . GLY D 1 399 ? 42.634  8.305   -4.723  1.00 26.63  ? 399 GLY D CA  1 
ATOM   12454 C C   . GLY D 1 399 ? 41.327  8.894   -4.247  1.00 28.37  ? 399 GLY D C   1 
ATOM   12455 O O   . GLY D 1 399 ? 41.126  10.109  -4.229  1.00 31.02  ? 399 GLY D O   1 
ATOM   12456 N N   . ALA D 1 400 ? 40.430  8.002   -3.844  1.00 28.93  ? 400 ALA D N   1 
ATOM   12457 C CA  . ALA D 1 400 ? 39.061  8.342   -3.506  1.00 27.55  ? 400 ALA D CA  1 
ATOM   12458 C C   . ALA D 1 400 ? 38.803  8.046   -2.039  1.00 23.08  ? 400 ALA D C   1 
ATOM   12459 O O   . ALA D 1 400 ? 39.386  7.125   -1.467  1.00 27.25  ? 400 ALA D O   1 
ATOM   12460 C CB  . ALA D 1 400 ? 38.071  7.554   -4.377  1.00 28.31  ? 400 ALA D CB  1 
ATOM   12461 N N   . VAL D 1 401 ? 37.936  8.850   -1.428  1.00 26.94  ? 401 VAL D N   1 
ATOM   12462 C CA  . VAL D 1 401 ? 37.376  8.553   -0.119  1.00 24.14  ? 401 VAL D CA  1 
ATOM   12463 C C   . VAL D 1 401 ? 35.863  8.568   -0.257  1.00 27.82  ? 401 VAL D C   1 
ATOM   12464 O O   . VAL D 1 401 ? 35.297  9.216   -1.146  1.00 24.03  ? 401 VAL D O   1 
ATOM   12465 C CB  . VAL D 1 401 ? 37.819  9.545   0.968   1.00 23.63  ? 401 VAL D CB  1 
ATOM   12466 C CG1 . VAL D 1 401 ? 39.306  9.453   1.173   1.00 23.82  ? 401 VAL D CG1 1 
ATOM   12467 C CG2 . VAL D 1 401 ? 37.398  10.957  0.580   1.00 24.86  ? 401 VAL D CG2 1 
ATOM   12468 N N   . VAL D 1 402 ? 35.211  7.855   0.648   1.00 22.08  ? 402 VAL D N   1 
ATOM   12469 C CA  . VAL D 1 402 ? 33.766  7.694   0.614   1.00 26.90  ? 402 VAL D CA  1 
ATOM   12470 C C   . VAL D 1 402 ? 33.140  8.744   1.526   1.00 29.88  ? 402 VAL D C   1 
ATOM   12471 O O   . VAL D 1 402 ? 33.475  8.830   2.712   1.00 30.88  ? 402 VAL D O   1 
ATOM   12472 C CB  . VAL D 1 402 ? 33.366  6.274   1.037   1.00 27.85  ? 402 VAL D CB  1 
ATOM   12473 C CG1 . VAL D 1 402 ? 31.847  6.142   1.212   1.00 26.11  ? 402 VAL D CG1 1 
ATOM   12474 C CG2 . VAL D 1 402 ? 33.871  5.293   0.022   1.00 27.08  ? 402 VAL D CG2 1 
ATOM   12475 N N   . LEU D 1 403 ? 32.237  9.551   0.974   1.00 27.49  ? 403 LEU D N   1 
ATOM   12476 C CA  . LEU D 1 403 ? 31.455  10.475  1.786   1.00 25.82  ? 403 LEU D CA  1 
ATOM   12477 C C   . LEU D 1 403 ? 30.063  9.947   2.106   1.00 30.50  ? 403 LEU D C   1 
ATOM   12478 O O   . LEU D 1 403 ? 29.478  10.351  3.113   1.00 27.64  ? 403 LEU D O   1 
ATOM   12479 C CB  . LEU D 1 403 ? 31.330  11.827  1.078   1.00 28.18  ? 403 LEU D CB  1 
ATOM   12480 C CG  . LEU D 1 403 ? 32.598  12.503  0.544   1.00 34.56  ? 403 LEU D CG  1 
ATOM   12481 C CD1 . LEU D 1 403 ? 32.331  13.962  0.399   1.00 33.10  ? 403 LEU D CD1 1 
ATOM   12482 C CD2 . LEU D 1 403 ? 33.815  12.294  1.445   1.00 25.63  ? 403 LEU D CD2 1 
ATOM   12483 N N   . GLY D 1 404 ? 29.519  9.060   1.268   1.00 32.39  ? 404 GLY D N   1 
ATOM   12484 C CA  . GLY D 1 404 ? 28.212  8.479   1.492   1.00 29.88  ? 404 GLY D CA  1 
ATOM   12485 C C   . GLY D 1 404 ? 28.059  7.139   0.804   1.00 31.99  ? 404 GLY D C   1 
ATOM   12486 O O   . GLY D 1 404 ? 28.459  6.979   -0.352  1.00 34.67  ? 404 GLY D O   1 
ATOM   12487 N N   . CYS D 1 405 ? 27.476  6.168   1.505   1.00 29.97  ? 405 CYS D N   1 
ATOM   12488 C CA  . CYS D 1 405 ? 27.228  4.850   0.939   1.00 37.27  ? 405 CYS D CA  1 
ATOM   12489 C C   . CYS D 1 405 ? 25.898  4.767   0.208   1.00 42.42  ? 405 CYS D C   1 
ATOM   12490 O O   . CYS D 1 405 ? 25.759  3.970   -0.729  1.00 35.77  ? 405 CYS D O   1 
ATOM   12491 C CB  . CYS D 1 405 ? 27.275  3.805   2.049   1.00 36.72  ? 405 CYS D CB  1 
ATOM   12492 S SG  . CYS D 1 405 ? 28.925  3.739   2.746   1.00 36.59  ? 405 CYS D SG  1 
ATOM   12493 N N   . ASN D 1 406 ? 24.927  5.583   0.615   1.00 39.27  ? 406 ASN D N   1 
ATOM   12494 C CA  . ASN D 1 406 ? 23.591  5.557   0.038   1.00 40.75  ? 406 ASN D CA  1 
ATOM   12495 C C   . ASN D 1 406 ? 22.894  6.874   0.335   1.00 37.22  ? 406 ASN D C   1 
ATOM   12496 O O   . ASN D 1 406 ? 22.075  6.956   1.251   1.00 40.20  ? 406 ASN D O   1 
ATOM   12497 C CB  . ASN D 1 406 ? 22.784  4.388   0.603   1.00 38.57  ? 406 ASN D CB  1 
ATOM   12498 C CG  . ASN D 1 406 ? 21.375  4.339   0.053   1.00 39.85  ? 406 ASN D CG  1 
ATOM   12499 O OD1 . ASN D 1 406 ? 21.106  4.817   -1.050  1.00 40.60  ? 406 ASN D OD1 1 
ATOM   12500 N ND2 . ASN D 1 406 ? 20.457  3.808   0.843   1.00 42.77  ? 406 ASN D ND2 1 
ATOM   12501 N N   . SER D 1 407 ? 23.228  7.915   -0.406  1.00 34.33  ? 407 SER D N   1 
ATOM   12502 C CA  . SER D 1 407 ? 22.760  9.250   -0.091  1.00 38.51  ? 407 SER D CA  1 
ATOM   12503 C C   . SER D 1 407 ? 21.751  9.705   -1.135  1.00 39.22  ? 407 SER D C   1 
ATOM   12504 O O   . SER D 1 407 ? 21.582  9.081   -2.186  1.00 36.30  ? 407 SER D O   1 
ATOM   12505 C CB  . SER D 1 407 ? 23.942  10.225  -0.005  1.00 34.50  ? 407 SER D CB  1 
ATOM   12506 O OG  . SER D 1 407 ? 23.545  11.564  -0.270  1.00 38.23  ? 407 SER D OG  1 
ATOM   12507 N N   . ASP D 1 408 ? 21.085  10.819  -0.835  1.00 43.34  ? 408 ASP D N   1 
ATOM   12508 C CA  . ASP D 1 408 ? 20.117  11.401  -1.753  1.00 39.41  ? 408 ASP D CA  1 
ATOM   12509 C C   . ASP D 1 408 ? 20.722  12.450  -2.671  1.00 42.11  ? 408 ASP D C   1 
ATOM   12510 O O   . ASP D 1 408 ? 20.022  12.941  -3.562  1.00 45.82  ? 408 ASP D O   1 
ATOM   12511 C CB  . ASP D 1 408 ? 18.950  12.000  -0.969  1.00 41.12  ? 408 ASP D CB  1 
ATOM   12512 C CG  . ASP D 1 408 ? 18.076  10.939  -0.336  1.00 46.90  ? 408 ASP D CG  1 
ATOM   12513 O OD1 . ASP D 1 408 ? 17.267  10.302  -1.055  1.00 51.91  ? 408 ASP D OD1 1 
ATOM   12514 O OD2 . ASP D 1 408 ? 18.219  10.719  0.882   1.00 49.14  ? 408 ASP D OD2 1 
ATOM   12515 N N   . LEU D 1 409 ? 22.007  12.770  -2.506  1.00 39.85  ? 409 LEU D N   1 
ATOM   12516 C CA  . LEU D 1 409 ? 22.609  13.858  -3.267  1.00 43.92  ? 409 LEU D CA  1 
ATOM   12517 C C   . LEU D 1 409 ? 22.449  13.642  -4.766  1.00 46.52  ? 409 LEU D C   1 
ATOM   12518 O O   . LEU D 1 409 ? 21.940  14.513  -5.480  1.00 49.59  ? 409 LEU D O   1 
ATOM   12519 C CB  . LEU D 1 409 ? 24.084  14.011  -2.887  1.00 40.69  ? 409 LEU D CB  1 
ATOM   12520 C CG  . LEU D 1 409 ? 24.321  14.762  -1.576  1.00 43.82  ? 409 LEU D CG  1 
ATOM   12521 C CD1 . LEU D 1 409 ? 25.685  15.450  -1.564  1.00 29.69  ? 409 LEU D CD1 1 
ATOM   12522 C CD2 . LEU D 1 409 ? 23.201  15.782  -1.327  1.00 43.38  ? 409 LEU D CD2 1 
ATOM   12523 N N   . GLY D 1 410 ? 22.877  12.491  -5.265  1.00 45.67  ? 410 GLY D N   1 
ATOM   12524 C CA  . GLY D 1 410 ? 22.628  12.150  -6.642  1.00 49.82  ? 410 GLY D CA  1 
ATOM   12525 C C   . GLY D 1 410 ? 21.596  11.048  -6.713  1.00 53.89  ? 410 GLY D C   1 
ATOM   12526 O O   . GLY D 1 410 ? 20.452  11.192  -6.272  1.00 50.05  ? 410 GLY D O   1 
ATOM   12527 N N   . PRO D 1 411 ? 21.991  9.904   -7.267  1.00 59.02  ? 411 PRO D N   1 
ATOM   12528 C CA  . PRO D 1 411 ? 21.185  8.684   -7.099  1.00 63.77  ? 411 PRO D CA  1 
ATOM   12529 C C   . PRO D 1 411 ? 21.736  7.714   -6.057  1.00 61.18  ? 411 PRO D C   1 
ATOM   12530 O O   . PRO D 1 411 ? 21.153  6.633   -5.899  1.00 65.20  ? 411 PRO D O   1 
ATOM   12531 C CB  . PRO D 1 411 ? 21.233  8.076   -8.507  1.00 62.88  ? 411 PRO D CB  1 
ATOM   12532 C CG  . PRO D 1 411 ? 22.535  8.546   -9.094  1.00 60.28  ? 411 PRO D CG  1 
ATOM   12533 C CD  . PRO D 1 411 ? 23.054  9.703   -8.259  1.00 55.50  ? 411 PRO D CD  1 
ATOM   12534 N N   . GLY D 1 412 ? 22.794  8.067   -5.318  1.00 47.72  ? 412 GLY D N   1 
ATOM   12535 C CA  . GLY D 1 412 ? 23.332  7.066   -4.412  1.00 45.28  ? 412 GLY D CA  1 
ATOM   12536 C C   . GLY D 1 412 ? 24.576  7.353   -3.595  1.00 43.04  ? 412 GLY D C   1 
ATOM   12537 O O   . GLY D 1 412 ? 24.551  8.191   -2.682  1.00 37.09  ? 412 GLY D O   1 
ATOM   12538 N N   . ALA D 1 413 ? 25.656  6.617   -3.879  1.00 38.02  ? 413 ALA D N   1 
ATOM   12539 C CA  . ALA D 1 413 ? 26.868  6.682   -3.074  1.00 37.46  ? 413 ALA D CA  1 
ATOM   12540 C C   . ALA D 1 413 ? 27.739  7.813   -3.572  1.00 31.98  ? 413 ALA D C   1 
ATOM   12541 O O   . ALA D 1 413 ? 27.807  8.070   -4.776  1.00 33.00  ? 413 ALA D O   1 
ATOM   12542 C CB  . ALA D 1 413 ? 27.644  5.364   -3.124  1.00 39.70  ? 413 ALA D CB  1 
ATOM   12543 N N   . GLU D 1 414 ? 28.401  8.494   -2.640  1.00 27.20  ? 414 GLU D N   1 
ATOM   12544 C CA  . GLU D 1 414 ? 29.140  9.712   -2.942  1.00 27.45  ? 414 GLU D CA  1 
ATOM   12545 C C   . GLU D 1 414 ? 30.614  9.472   -2.647  1.00 24.11  ? 414 GLU D C   1 
ATOM   12546 O O   . GLU D 1 414 ? 30.975  9.092   -1.534  1.00 24.34  ? 414 GLU D O   1 
ATOM   12547 C CB  . GLU D 1 414 ? 28.598  10.917  -2.143  1.00 28.33  ? 414 GLU D CB  1 
ATOM   12548 C CG  . GLU D 1 414 ? 29.385  12.231  -2.359  1.00 23.88  ? 414 GLU D CG  1 
ATOM   12549 C CD  . GLU D 1 414 ? 28.979  13.367  -1.409  1.00 29.69  ? 414 GLU D CD  1 
ATOM   12550 O OE1 . GLU D 1 414 ? 28.473  13.104  -0.289  1.00 28.61  ? 414 GLU D OE1 1 
ATOM   12551 O OE2 . GLU D 1 414 ? 29.180  14.543  -1.788  1.00 29.05  ? 414 GLU D OE2 1 
ATOM   12552 N N   . LEU D 1 415 ? 31.452  9.732   -3.634  1.00 26.47  ? 415 LEU D N   1 
ATOM   12553 C CA  . LEU D 1 415 ? 32.889  9.527   -3.575  1.00 24.67  ? 415 LEU D CA  1 
ATOM   12554 C C   . LEU D 1 415 ? 33.600  10.824  -3.926  1.00 26.35  ? 415 LEU D C   1 
ATOM   12555 O O   . LEU D 1 415 ? 33.153  11.566  -4.814  1.00 26.22  ? 415 LEU D O   1 
ATOM   12556 C CB  . LEU D 1 415 ? 33.329  8.458   -4.579  1.00 23.28  ? 415 LEU D CB  1 
ATOM   12557 C CG  . LEU D 1 415 ? 32.934  7.001   -4.443  1.00 26.81  ? 415 LEU D CG  1 
ATOM   12558 C CD1 . LEU D 1 415 ? 33.693  6.224   -5.487  1.00 35.20  ? 415 LEU D CD1 1 
ATOM   12559 C CD2 . LEU D 1 415 ? 33.270  6.475   -3.082  1.00 28.63  ? 415 LEU D CD2 1 
ATOM   12560 N N   . LEU D 1 416 ? 34.735  11.063  -3.274  1.00 25.65  ? 416 LEU D N   1 
ATOM   12561 C CA  . LEU D 1 416 ? 35.585  12.220  -3.542  1.00 25.18  ? 416 LEU D CA  1 
ATOM   12562 C C   . LEU D 1 416 ? 36.979  11.750  -3.944  1.00 27.96  ? 416 LEU D C   1 
ATOM   12563 O O   . LEU D 1 416 ? 37.648  11.059  -3.165  1.00 26.99  ? 416 LEU D O   1 
ATOM   12564 C CB  . LEU D 1 416 ? 35.662  13.120  -2.316  1.00 23.99  ? 416 LEU D CB  1 
ATOM   12565 C CG  . LEU D 1 416 ? 36.499  14.379  -2.484  1.00 29.05  ? 416 LEU D CG  1 
ATOM   12566 C CD1 . LEU D 1 416 ? 35.913  15.233  -3.583  1.00 30.13  ? 416 LEU D CD1 1 
ATOM   12567 C CD2 . LEU D 1 416 ? 36.559  15.131  -1.162  1.00 26.97  ? 416 LEU D CD2 1 
ATOM   12568 N N   . VAL D 1 417 ? 37.433  12.172  -5.128  1.00 25.78  ? 417 VAL D N   1 
ATOM   12569 C CA  . VAL D 1 417 ? 38.622  11.634  -5.779  1.00 26.95  ? 417 VAL D CA  1 
ATOM   12570 C C   . VAL D 1 417 ? 39.631  12.754  -5.984  1.00 32.76  ? 417 VAL D C   1 
ATOM   12571 O O   . VAL D 1 417 ? 39.300  13.789  -6.582  1.00 27.18  ? 417 VAL D O   1 
ATOM   12572 C CB  . VAL D 1 417 ? 38.286  10.990  -7.139  1.00 30.79  ? 417 VAL D CB  1 
ATOM   12573 C CG1 . VAL D 1 417 ? 39.465  10.160  -7.623  1.00 28.29  ? 417 VAL D CG1 1 
ATOM   12574 C CG2 . VAL D 1 417 ? 37.008  10.161  -7.051  1.00 28.36  ? 417 VAL D CG2 1 
ATOM   12575 N N   . PHE D 1 418 ? 40.869  12.514  -5.535  1.00 26.92  ? 418 PHE D N   1 
ATOM   12576 C CA  . PHE D 1 418 ? 41.986  13.447  -5.596  1.00 25.95  ? 418 PHE D CA  1 
ATOM   12577 C C   . PHE D 1 418 ? 43.048  12.947  -6.566  1.00 28.05  ? 418 PHE D C   1 
ATOM   12578 O O   . PHE D 1 418 ? 43.245  11.739  -6.739  1.00 33.70  ? 418 PHE D O   1 
ATOM   12579 C CB  . PHE D 1 418 ? 42.644  13.642  -4.216  1.00 22.01  ? 418 PHE D CB  1 
ATOM   12580 C CG  . PHE D 1 418 ? 41.711  14.159  -3.166  1.00 29.29  ? 418 PHE D CG  1 
ATOM   12581 C CD1 . PHE D 1 418 ? 40.997  13.289  -2.365  1.00 28.99  ? 418 PHE D CD1 1 
ATOM   12582 C CD2 . PHE D 1 418 ? 41.538  15.522  -2.977  1.00 30.24  ? 418 PHE D CD2 1 
ATOM   12583 C CE1 . PHE D 1 418 ? 40.124  13.770  -1.391  1.00 29.58  ? 418 PHE D CE1 1 
ATOM   12584 C CE2 . PHE D 1 418 ? 40.678  15.994  -2.007  1.00 23.85  ? 418 PHE D CE2 1 
ATOM   12585 C CZ  . PHE D 1 418 ? 39.974  15.112  -1.219  1.00 27.94  ? 418 PHE D CZ  1 
ATOM   12586 N N   . SER D 1 419 ? 43.758  13.890  -7.170  1.00 28.45  ? 419 SER D N   1 
ATOM   12587 C CA  . SER D 1 419 ? 44.870  13.569  -8.050  1.00 27.89  ? 419 SER D CA  1 
ATOM   12588 C C   . SER D 1 419 ? 45.641  14.842  -8.333  1.00 32.58  ? 419 SER D C   1 
ATOM   12589 O O   . SER D 1 419 ? 45.068  15.934  -8.371  1.00 29.23  ? 419 SER D O   1 
ATOM   12590 C CB  . SER D 1 419 ? 44.404  12.945  -9.373  1.00 33.82  ? 419 SER D CB  1 
ATOM   12591 O OG  . SER D 1 419 ? 45.514  12.672  -10.218 1.00 37.13  ? 419 SER D OG  1 
ATOM   12592 N N   . LYS D 1 420 ? 46.942  14.688  -8.547  1.00 34.70  ? 420 LYS D N   1 
ATOM   12593 C CA  . LYS D 1 420 ? 47.759  15.827  -8.916  1.00 34.58  ? 420 LYS D CA  1 
ATOM   12594 C C   . LYS D 1 420 ? 47.712  16.100  -10.410 1.00 34.16  ? 420 LYS D C   1 
ATOM   12595 O O   . LYS D 1 420 ? 48.158  17.161  -10.851 1.00 33.19  ? 420 LYS D O   1 
ATOM   12596 C CB  . LYS D 1 420 ? 49.189  15.583  -8.443  1.00 38.01  ? 420 LYS D CB  1 
ATOM   12597 C CG  . LYS D 1 420 ? 49.233  14.911  -7.064  1.00 38.52  ? 420 LYS D CG  1 
ATOM   12598 C CD  . LYS D 1 420 ? 50.339  15.475  -6.193  1.00 35.61  ? 420 LYS D CD  1 
ATOM   12599 C CE  . LYS D 1 420 ? 51.542  14.574  -6.212  1.00 32.60  ? 420 LYS D CE  1 
ATOM   12600 N NZ  . LYS D 1 420 ? 51.381  13.441  -5.269  1.00 45.36  ? 420 LYS D NZ  1 
ATOM   12601 N N   . ASP D 1 421 ? 47.168  15.179  -11.191 1.00 40.00  ? 421 ASP D N   1 
ATOM   12602 C CA  . ASP D 1 421 ? 47.009  15.355  -12.624 1.00 41.49  ? 421 ASP D CA  1 
ATOM   12603 C C   . ASP D 1 421 ? 45.531  15.252  -12.947 1.00 38.92  ? 421 ASP D C   1 
ATOM   12604 O O   . ASP D 1 421 ? 44.847  14.351  -12.454 1.00 38.13  ? 421 ASP D O   1 
ATOM   12605 C CB  . ASP D 1 421 ? 47.812  14.311  -13.398 1.00 44.88  ? 421 ASP D CB  1 
ATOM   12606 C CG  . ASP D 1 421 ? 48.012  14.685  -14.845 1.00 43.88  ? 421 ASP D CG  1 
ATOM   12607 O OD1 . ASP D 1 421 ? 47.039  14.624  -15.616 1.00 50.16  ? 421 ASP D OD1 1 
ATOM   12608 O OD2 . ASP D 1 421 ? 49.146  15.036  -15.216 1.00 50.89  ? 421 ASP D OD2 1 
ATOM   12609 N N   . TRP D 1 422 ? 45.033  16.194  -13.743 1.00 45.00  ? 422 TRP D N   1 
ATOM   12610 C CA  . TRP D 1 422 ? 43.609  16.190  -14.046 1.00 47.54  ? 422 TRP D CA  1 
ATOM   12611 C C   . TRP D 1 422 ? 43.240  15.018  -14.948 1.00 45.08  ? 422 TRP D C   1 
ATOM   12612 O O   . TRP D 1 422 ? 42.168  14.423  -14.789 1.00 45.84  ? 422 TRP D O   1 
ATOM   12613 C CB  . TRP D 1 422 ? 43.208  17.512  -14.682 1.00 50.68  ? 422 TRP D CB  1 
ATOM   12614 C CG  . TRP D 1 422 ? 41.795  17.535  -15.127 1.00 59.42  ? 422 TRP D CG  1 
ATOM   12615 C CD1 . TRP D 1 422 ? 40.684  17.449  -14.339 1.00 63.81  ? 422 TRP D CD1 1 
ATOM   12616 C CD2 . TRP D 1 422 ? 41.330  17.656  -16.473 1.00 62.53  ? 422 TRP D CD2 1 
ATOM   12617 N NE1 . TRP D 1 422 ? 39.554  17.511  -15.115 1.00 65.35  ? 422 TRP D NE1 1 
ATOM   12618 C CE2 . TRP D 1 422 ? 39.924  17.639  -16.430 1.00 70.11  ? 422 TRP D CE2 1 
ATOM   12619 C CE3 . TRP D 1 422 ? 41.966  17.781  -17.711 1.00 64.95  ? 422 TRP D CE3 1 
ATOM   12620 C CZ2 . TRP D 1 422 ? 39.141  17.739  -17.582 1.00 77.36  ? 422 TRP D CZ2 1 
ATOM   12621 C CZ3 . TRP D 1 422 ? 41.193  17.883  -18.848 1.00 71.17  ? 422 TRP D CZ3 1 
ATOM   12622 C CH2 . TRP D 1 422 ? 39.795  17.862  -18.778 1.00 74.72  ? 422 TRP D CH2 1 
ATOM   12623 N N   . ASP D 1 423 ? 44.120  14.664  -15.892 1.00 41.66  ? 423 ASP D N   1 
ATOM   12624 C CA  . ASP D 1 423 ? 43.849  13.530  -16.773 1.00 45.37  ? 423 ASP D CA  1 
ATOM   12625 C C   . ASP D 1 423 ? 43.822  12.216  -15.994 1.00 44.40  ? 423 ASP D C   1 
ATOM   12626 O O   . ASP D 1 423 ? 43.003  11.332  -16.284 1.00 40.61  ? 423 ASP D O   1 
ATOM   12627 C CB  . ASP D 1 423 ? 44.895  13.471  -17.894 1.00 48.07  ? 423 ASP D CB  1 
ATOM   12628 C CG  . ASP D 1 423 ? 45.050  14.797  -18.621 1.00 52.08  ? 423 ASP D CG  1 
ATOM   12629 O OD1 . ASP D 1 423 ? 44.220  15.085  -19.509 1.00 54.04  ? 423 ASP D OD1 1 
ATOM   12630 O OD2 . ASP D 1 423 ? 45.993  15.559  -18.295 1.00 55.16  ? 423 ASP D OD2 1 
ATOM   12631 N N   . ARG D 1 424 ? 44.704  12.076  -14.997 1.00 39.48  ? 424 ARG D N   1 
ATOM   12632 C CA  . ARG D 1 424 ? 44.678  10.897  -14.135 1.00 38.59  ? 424 ARG D CA  1 
ATOM   12633 C C   . ARG D 1 424 ? 43.417  10.853  -13.278 1.00 38.33  ? 424 ARG D C   1 
ATOM   12634 O O   . ARG D 1 424 ? 42.802  9.787   -13.138 1.00 38.10  ? 424 ARG D O   1 
ATOM   12635 C CB  . ARG D 1 424 ? 45.924  10.863  -13.253 1.00 38.67  ? 424 ARG D CB  1 
ATOM   12636 C CG  . ARG D 1 424 ? 47.106  10.133  -13.871 1.00 42.69  ? 424 ARG D CG  1 
ATOM   12637 C CD  . ARG D 1 424 ? 47.892  9.349   -12.813 1.00 48.21  ? 424 ARG D CD  1 
ATOM   12638 N NE  . ARG D 1 424 ? 48.257  10.186  -11.673 1.00 50.28  ? 424 ARG D NE  1 
ATOM   12639 C CZ  . ARG D 1 424 ? 49.003  11.281  -11.750 1.00 47.33  ? 424 ARG D CZ  1 
ATOM   12640 N NH1 . ARG D 1 424 ? 49.584  11.647  -12.884 1.00 51.74  ? 424 ARG D NH1 1 
ATOM   12641 N NH2 . ARG D 1 424 ? 49.190  12.018  -10.657 1.00 39.09  ? 424 ARG D NH2 1 
ATOM   12642 N N   . LEU D 1 425 ? 43.018  11.990  -12.689 1.00 37.08  ? 425 LEU D N   1 
ATOM   12643 C CA  . LEU D 1 425 ? 41.751  12.037  -11.956 1.00 33.84  ? 425 LEU D CA  1 
ATOM   12644 C C   . LEU D 1 425 ? 40.628  11.458  -12.798 1.00 32.75  ? 425 LEU D C   1 
ATOM   12645 O O   . LEU D 1 425 ? 39.864  10.597  -12.344 1.00 32.36  ? 425 LEU D O   1 
ATOM   12646 C CB  . LEU D 1 425 ? 41.399  13.476  -11.554 1.00 32.39  ? 425 LEU D CB  1 
ATOM   12647 C CG  . LEU D 1 425 ? 40.541  13.762  -10.298 1.00 33.13  ? 425 LEU D CG  1 
ATOM   12648 C CD1 . LEU D 1 425 ? 40.215  15.265  -10.161 1.00 34.54  ? 425 LEU D CD1 1 
ATOM   12649 C CD2 . LEU D 1 425 ? 39.255  12.948  -10.212 1.00 30.14  ? 425 LEU D CD2 1 
ATOM   12650 N N   . THR D 1 426 ? 40.511  11.934  -14.032 1.00 32.19  ? 426 THR D N   1 
ATOM   12651 C CA  . THR D 1 426 ? 39.484  11.419  -14.930 1.00 38.16  ? 426 THR D CA  1 
ATOM   12652 C C   . THR D 1 426 ? 39.564  9.897   -15.049 1.00 34.67  ? 426 THR D C   1 
ATOM   12653 O O   . THR D 1 426 ? 38.560  9.197   -14.888 1.00 37.33  ? 426 THR D O   1 
ATOM   12654 C CB  . THR D 1 426 ? 39.634  12.070  -16.301 1.00 38.05  ? 426 THR D CB  1 
ATOM   12655 O OG1 . THR D 1 426 ? 39.311  13.459  -16.196 1.00 45.01  ? 426 THR D OG1 1 
ATOM   12656 C CG2 . THR D 1 426 ? 38.698  11.416  -17.298 1.00 44.15  ? 426 THR D CG2 1 
ATOM   12657 N N   . ALA D 1 427 ? 40.759  9.369   -15.323 1.00 33.67  ? 427 ALA D N   1 
ATOM   12658 C CA  . ALA D 1 427 ? 40.906  7.922   -15.489 1.00 37.65  ? 427 ALA D CA  1 
ATOM   12659 C C   . ALA D 1 427 ? 40.442  7.180   -14.242 1.00 39.70  ? 427 ALA D C   1 
ATOM   12660 O O   . ALA D 1 427 ? 39.760  6.151   -14.337 1.00 36.47  ? 427 ALA D O   1 
ATOM   12661 C CB  . ALA D 1 427 ? 42.359  7.571   -15.820 1.00 35.05  ? 427 ALA D CB  1 
ATOM   12662 N N   . MET D 1 428 ? 40.766  7.718   -13.060 1.00 34.31  ? 428 MET D N   1 
ATOM   12663 C CA  . MET D 1 428 ? 40.266  7.144   -11.816 1.00 31.63  ? 428 MET D CA  1 
ATOM   12664 C C   . MET D 1 428 ? 38.738  7.154   -11.771 1.00 34.65  ? 428 MET D C   1 
ATOM   12665 O O   . MET D 1 428 ? 38.120  6.210   -11.264 1.00 37.38  ? 428 MET D O   1 
ATOM   12666 C CB  . MET D 1 428 ? 40.843  7.919   -10.636 1.00 29.11  ? 428 MET D CB  1 
ATOM   12667 C CG  . MET D 1 428 ? 42.351  8.007   -10.664 1.00 34.64  ? 428 MET D CG  1 
ATOM   12668 S SD  . MET D 1 428 ? 42.976  9.065   -9.354  1.00 45.19  ? 428 MET D SD  1 
ATOM   12669 C CE  . MET D 1 428 ? 42.499  8.049   -7.997  1.00 33.91  ? 428 MET D CE  1 
ATOM   12670 N N   . LYS D 1 429 ? 38.105  8.220   -12.281 1.00 32.43  ? 429 LYS D N   1 
ATOM   12671 C CA  . LYS D 1 429 ? 36.645  8.267   -12.255 1.00 38.76  ? 429 LYS D CA  1 
ATOM   12672 C C   . LYS D 1 429 ? 36.047  7.210   -13.177 1.00 33.53  ? 429 LYS D C   1 
ATOM   12673 O O   . LYS D 1 429 ? 35.104  6.509   -12.797 1.00 33.84  ? 429 LYS D O   1 
ATOM   12674 C CB  . LYS D 1 429 ? 36.131  9.671   -12.615 1.00 36.58  ? 429 LYS D CB  1 
ATOM   12675 C CG  . LYS D 1 429 ? 36.762  10.814  -11.809 1.00 35.72  ? 429 LYS D CG  1 
ATOM   12676 C CD  . LYS D 1 429 ? 35.721  11.718  -11.158 1.00 30.99  ? 429 LYS D CD  1 
ATOM   12677 C CE  . LYS D 1 429 ? 34.842  12.378  -12.186 1.00 38.16  ? 429 LYS D CE  1 
ATOM   12678 N NZ  . LYS D 1 429 ? 35.394  13.683  -12.671 1.00 45.19  ? 429 LYS D NZ  1 
ATOM   12679 N N   . ASP D 1 430 ? 36.603  7.049   -14.375 1.00 37.15  ? 430 ASP D N   1 
ATOM   12680 C CA  . ASP D 1 430 ? 36.144  5.965   -15.242 1.00 43.34  ? 430 ASP D CA  1 
ATOM   12681 C C   . ASP D 1 430 ? 36.290  4.623   -14.552 1.00 39.77  ? 430 ASP D C   1 
ATOM   12682 O O   . ASP D 1 430 ? 35.344  3.826   -14.514 1.00 34.96  ? 430 ASP D O   1 
ATOM   12683 C CB  . ASP D 1 430 ? 36.915  5.968   -16.556 1.00 41.07  ? 430 ASP D CB  1 
ATOM   12684 C CG  . ASP D 1 430 ? 36.567  7.153   -17.398 1.00 51.26  ? 430 ASP D CG  1 
ATOM   12685 O OD1 . ASP D 1 430 ? 35.359  7.467   -17.447 1.00 53.42  ? 430 ASP D OD1 1 
ATOM   12686 O OD2 . ASP D 1 430 ? 37.476  7.764   -18.003 1.00 55.27  ? 430 ASP D OD2 1 
ATOM   12687 N N   . GLU D 1 431 ? 37.477  4.361   -13.991 1.00 41.33  ? 431 GLU D N   1 
ATOM   12688 C CA  . GLU D 1 431 ? 37.721  3.079   -13.347 1.00 38.48  ? 431 GLU D CA  1 
ATOM   12689 C C   . GLU D 1 431 ? 36.735  2.857   -12.216 1.00 38.15  ? 431 GLU D C   1 
ATOM   12690 O O   . GLU D 1 431 ? 36.238  1.740   -12.021 1.00 36.32  ? 431 GLU D O   1 
ATOM   12691 C CB  . GLU D 1 431 ? 39.161  3.018   -12.848 1.00 37.29  ? 431 GLU D CB  1 
ATOM   12692 C CG  . GLU D 1 431 ? 40.141  2.492   -13.891 1.00 46.74  ? 431 GLU D CG  1 
ATOM   12693 C CD  . GLU D 1 431 ? 40.337  0.985   -13.807 1.00 51.55  ? 431 GLU D CD  1 
ATOM   12694 O OE1 . GLU D 1 431 ? 39.483  0.235   -14.330 1.00 52.22  ? 431 GLU D OE1 1 
ATOM   12695 O OE2 . GLU D 1 431 ? 41.347  0.551   -13.208 1.00 53.96  ? 431 GLU D OE2 1 
ATOM   12696 N N   . ILE D 1 432 ? 36.390  3.927   -11.498 1.00 33.16  ? 432 ILE D N   1 
ATOM   12697 C CA  . ILE D 1 432 ? 35.447  3.783   -10.398 1.00 35.90  ? 432 ILE D CA  1 
ATOM   12698 C C   . ILE D 1 432 ? 34.076  3.389   -10.932 1.00 36.64  ? 432 ILE D C   1 
ATOM   12699 O O   . ILE D 1 432 ? 33.372  2.556   -10.341 1.00 34.30  ? 432 ILE D O   1 
ATOM   12700 C CB  . ILE D 1 432 ? 35.396  5.080   -9.566  1.00 38.25  ? 432 ILE D CB  1 
ATOM   12701 C CG1 . ILE D 1 432 ? 36.612  5.165   -8.635  1.00 38.61  ? 432 ILE D CG1 1 
ATOM   12702 C CG2 . ILE D 1 432 ? 34.119  5.133   -8.751  1.00 36.17  ? 432 ILE D CG2 1 
ATOM   12703 C CD1 . ILE D 1 432 ? 36.796  6.501   -7.920  1.00 27.69  ? 432 ILE D CD1 1 
ATOM   12704 N N   . ALA D 1 433 ? 33.666  3.990   -12.049 1.00 34.34  ? 433 ALA D N   1 
ATOM   12705 C CA  . ALA D 1 433 ? 32.371  3.639   -12.624 1.00 39.02  ? 433 ALA D CA  1 
ATOM   12706 C C   . ALA D 1 433 ? 32.407  2.239   -13.221 1.00 41.68  ? 433 ALA D C   1 
ATOM   12707 O O   . ALA D 1 433 ? 31.456  1.465   -13.067 1.00 39.26  ? 433 ALA D O   1 
ATOM   12708 C CB  . ALA D 1 433 ? 31.959  4.660   -13.676 1.00 39.33  ? 433 ALA D CB  1 
ATOM   12709 N N   . THR D 1 434 ? 33.502  1.898   -13.908 1.00 42.29  ? 434 THR D N   1 
ATOM   12710 C CA  . THR D 1 434 ? 33.695  0.526   -14.378 1.00 40.99  ? 434 THR D CA  1 
ATOM   12711 C C   . THR D 1 434 ? 33.499  -0.486  -13.256 1.00 44.91  ? 434 THR D C   1 
ATOM   12712 O O   . THR D 1 434 ? 32.869  -1.533  -13.454 1.00 43.52  ? 434 THR D O   1 
ATOM   12713 C CB  . THR D 1 434 ? 35.096  0.355   -14.975 1.00 43.26  ? 434 THR D CB  1 
ATOM   12714 O OG1 . THR D 1 434 ? 35.175  1.031   -16.239 1.00 47.63  ? 434 THR D OG1 1 
ATOM   12715 C CG2 . THR D 1 434 ? 35.451  -1.131  -15.146 1.00 40.03  ? 434 THR D CG2 1 
ATOM   12716 N N   . THR D 1 435 ? 34.022  -0.189  -12.066 1.00 42.26  ? 435 THR D N   1 
ATOM   12717 C CA  . THR D 1 435 ? 34.156  -1.174  -11.000 1.00 34.99  ? 435 THR D CA  1 
ATOM   12718 C C   . THR D 1 435 ? 33.068  -1.091  -9.945  1.00 40.96  ? 435 THR D C   1 
ATOM   12719 O O   . THR D 1 435 ? 32.560  -2.131  -9.507  1.00 46.88  ? 435 THR D O   1 
ATOM   12720 C CB  . THR D 1 435 ? 35.521  -1.017  -10.331 1.00 42.14  ? 435 THR D CB  1 
ATOM   12721 O OG1 . THR D 1 435 ? 36.555  -1.310  -11.283 1.00 49.00  ? 435 THR D OG1 1 
ATOM   12722 C CG2 . THR D 1 435 ? 35.637  -1.925  -9.130  1.00 40.10  ? 435 THR D CG2 1 
ATOM   12723 N N   . ALA D 1 436 ? 32.706  0.113   -9.497  1.00 41.23  ? 436 ALA D N   1 
ATOM   12724 C CA  . ALA D 1 436 ? 31.602  0.229   -8.555  1.00 42.34  ? 436 ALA D CA  1 
ATOM   12725 C C   . ALA D 1 436 ? 30.262  0.394   -9.254  1.00 40.77  ? 436 ALA D C   1 
ATOM   12726 O O   . ALA D 1 436 ? 29.224  0.095   -8.654  1.00 41.02  ? 436 ALA D O   1 
ATOM   12727 C CB  . ALA D 1 436 ? 31.827  1.396   -7.594  1.00 37.43  ? 436 ALA D CB  1 
ATOM   12728 N N   . GLY D 1 437 ? 30.261  0.840   -10.508 1.00 39.43  ? 437 GLY D N   1 
ATOM   12729 C CA  . GLY D 1 437 ? 29.021  0.967   -11.250 1.00 43.05  ? 437 GLY D CA  1 
ATOM   12730 C C   . GLY D 1 437 ? 28.276  2.242   -10.914 1.00 44.94  ? 437 GLY D C   1 
ATOM   12731 O O   . GLY D 1 437 ? 28.331  2.721   -9.775  1.00 44.01  ? 437 GLY D O   1 
ATOM   12732 N N   . THR D 1 438 ? 27.573  2.809   -11.886 1.00 43.73  ? 438 THR D N   1 
ATOM   12733 C CA  . THR D 1 438 ? 26.871  4.061   -11.659 1.00 49.47  ? 438 THR D CA  1 
ATOM   12734 C C   . THR D 1 438 ? 25.414  3.924   -12.065 1.00 49.54  ? 438 THR D C   1 
ATOM   12735 O O   . THR D 1 438 ? 25.058  3.102   -12.916 1.00 52.97  ? 438 THR D O   1 
ATOM   12736 C CB  . THR D 1 438 ? 27.526  5.249   -12.420 1.00 50.50  ? 438 THR D CB  1 
ATOM   12737 O OG1 . THR D 1 438 ? 27.634  4.949   -13.818 1.00 55.12  ? 438 THR D OG1 1 
ATOM   12738 C CG2 . THR D 1 438 ? 28.906  5.546   -11.861 1.00 44.03  ? 438 THR D CG2 1 
ATOM   12739 N N   . LEU D 1 439 ? 24.575  4.739   -11.430 1.00 53.19  ? 439 LEU D N   1 
ATOM   12740 C CA  . LEU D 1 439 ? 23.158  4.829   -11.767 1.00 53.28  ? 439 LEU D CA  1 
ATOM   12741 C C   . LEU D 1 439 ? 23.028  5.860   -12.880 1.00 57.12  ? 439 LEU D C   1 
ATOM   12742 O O   . LEU D 1 439 ? 22.907  7.059   -12.632 1.00 59.94  ? 439 LEU D O   1 
ATOM   12743 C CB  . LEU D 1 439 ? 22.334  5.197   -10.541 1.00 50.62  ? 439 LEU D CB  1 
ATOM   12744 C CG  . LEU D 1 439 ? 22.391  4.178   -9.400  1.00 49.85  ? 439 LEU D CG  1 
ATOM   12745 C CD1 . LEU D 1 439 ? 21.649  4.679   -8.187  1.00 46.43  ? 439 LEU D CD1 1 
ATOM   12746 C CD2 . LEU D 1 439 ? 21.825  2.842   -9.828  1.00 46.90  ? 439 LEU D CD2 1 
ATOM   12747 N N   . SER D 1 440 ? 23.091  5.377   -14.123 1.00 62.72  ? 440 SER D N   1 
ATOM   12748 C CA  . SER D 1 440 ? 22.930  6.182   -15.343 1.00 62.09  ? 440 SER D CA  1 
ATOM   12749 C C   . SER D 1 440 ? 24.003  7.261   -15.499 1.00 61.41  ? 440 SER D C   1 
ATOM   12750 O O   . SER D 1 440 ? 24.023  8.002   -16.485 1.00 49.73  ? 440 SER D O   1 
ATOM   12751 C CB  . SER D 1 440 ? 21.529  6.815   -15.391 1.00 66.28  ? 440 SER D CB  1 
ATOM   12752 O OG  . SER D 1 440 ? 20.521  5.879   -15.026 1.00 60.07  ? 440 SER D OG  1 
ATOM   12753 N N   . PRO E 1 2   ? 46.500  -19.847 43.794  1.00 52.03  ? 2   PRO E N   1 
ATOM   12754 C CA  . PRO E 1 2   ? 47.757  -20.587 43.940  1.00 40.78  ? 2   PRO E CA  1 
ATOM   12755 C C   . PRO E 1 2   ? 48.902  -19.703 44.442  1.00 39.89  ? 2   PRO E C   1 
ATOM   12756 O O   . PRO E 1 2   ? 49.161  -18.624 43.886  1.00 36.08  ? 2   PRO E O   1 
ATOM   12757 C CB  . PRO E 1 2   ? 48.028  -21.085 42.521  1.00 43.26  ? 2   PRO E CB  1 
ATOM   12758 C CG  . PRO E 1 2   ? 47.406  -20.046 41.649  1.00 41.04  ? 2   PRO E CG  1 
ATOM   12759 C CD  . PRO E 1 2   ? 46.175  -19.580 42.380  1.00 52.35  ? 2   PRO E CD  1 
ATOM   12760 N N   . LYS E 1 3   ? 49.569  -20.156 45.502  1.00 32.87  ? 3   LYS E N   1 
ATOM   12761 C CA  . LYS E 1 3   ? 50.711  -19.443 46.047  1.00 36.62  ? 3   LYS E CA  1 
ATOM   12762 C C   . LYS E 1 3   ? 51.831  -20.432 46.323  1.00 32.97  ? 3   LYS E C   1 
ATOM   12763 O O   . LYS E 1 3   ? 51.597  -21.628 46.531  1.00 29.90  ? 3   LYS E O   1 
ATOM   12764 C CB  . LYS E 1 3   ? 50.346  -18.666 47.330  1.00 32.50  ? 3   LYS E CB  1 
ATOM   12765 C CG  . LYS E 1 3   ? 50.195  -19.512 48.600  1.00 28.29  ? 3   LYS E CG  1 
ATOM   12766 C CD  . LYS E 1 3   ? 49.442  -18.727 49.696  1.00 29.43  ? 3   LYS E CD  1 
ATOM   12767 C CE  . LYS E 1 3   ? 49.053  -19.589 50.918  1.00 28.29  ? 3   LYS E CE  1 
ATOM   12768 N NZ  . LYS E 1 3   ? 47.778  -20.381 50.699  1.00 31.76  ? 3   LYS E NZ  1 
ATOM   12769 N N   . ILE E 1 4   ? 53.056  -19.907 46.321  1.00 31.81  ? 4   ILE E N   1 
ATOM   12770 C CA  . ILE E 1 4   ? 54.245  -20.647 46.727  1.00 30.31  ? 4   ILE E CA  1 
ATOM   12771 C C   . ILE E 1 4   ? 54.516  -20.320 48.192  1.00 29.43  ? 4   ILE E C   1 
ATOM   12772 O O   . ILE E 1 4   ? 54.774  -19.160 48.542  1.00 28.45  ? 4   ILE E O   1 
ATOM   12773 C CB  . ILE E 1 4   ? 55.447  -20.296 45.841  1.00 30.32  ? 4   ILE E CB  1 
ATOM   12774 C CG1 . ILE E 1 4   ? 55.110  -20.562 44.376  1.00 35.42  ? 4   ILE E CG1 1 
ATOM   12775 C CG2 . ILE E 1 4   ? 56.694  -21.067 46.268  1.00 28.26  ? 4   ILE E CG2 1 
ATOM   12776 C CD1 . ILE E 1 4   ? 55.696  -19.563 43.421  1.00 27.83  ? 4   ILE E CD1 1 
ATOM   12777 N N   . ILE E 1 5   ? 54.421  -21.337 49.042  1.00 26.10  ? 5   ILE E N   1 
ATOM   12778 C CA  . ILE E 1 5   ? 54.627  -21.213 50.484  1.00 29.59  ? 5   ILE E CA  1 
ATOM   12779 C C   . ILE E 1 5   ? 56.111  -21.436 50.742  1.00 33.87  ? 5   ILE E C   1 
ATOM   12780 O O   . ILE E 1 5   ? 56.615  -22.537 50.517  1.00 30.72  ? 5   ILE E O   1 
ATOM   12781 C CB  . ILE E 1 5   ? 53.784  -22.231 51.267  1.00 28.09  ? 5   ILE E CB  1 
ATOM   12782 C CG1 . ILE E 1 5   ? 52.284  -21.990 51.069  1.00 27.08  ? 5   ILE E CG1 1 
ATOM   12783 C CG2 . ILE E 1 5   ? 54.171  -22.258 52.742  1.00 23.17  ? 5   ILE E CG2 1 
ATOM   12784 C CD1 . ILE E 1 5   ? 51.460  -23.229 51.372  1.00 26.17  ? 5   ILE E CD1 1 
ATOM   12785 N N   . LEU E 1 6   ? 56.802  -20.405 51.239  1.00 26.55  ? 6   LEU E N   1 
ATOM   12786 C CA  . LEU E 1 6   ? 58.263  -20.347 51.241  1.00 28.24  ? 6   LEU E CA  1 
ATOM   12787 C C   . LEU E 1 6   ? 58.803  -20.141 52.654  1.00 30.95  ? 6   LEU E C   1 
ATOM   12788 O O   . LEU E 1 6   ? 58.992  -18.994 53.082  1.00 25.70  ? 6   LEU E O   1 
ATOM   12789 C CB  . LEU E 1 6   ? 58.714  -19.216 50.319  1.00 29.85  ? 6   LEU E CB  1 
ATOM   12790 C CG  . LEU E 1 6   ? 60.137  -19.146 49.745  1.00 32.90  ? 6   LEU E CG  1 
ATOM   12791 C CD1 . LEU E 1 6   ? 60.724  -17.721 49.852  1.00 23.83  ? 6   LEU E CD1 1 
ATOM   12792 C CD2 . LEU E 1 6   ? 61.026  -20.125 50.416  1.00 35.39  ? 6   LEU E CD2 1 
ATOM   12793 N N   . PRO E 1 7   ? 59.141  -21.245 53.418  1.00 30.87  ? 7   PRO E N   1 
ATOM   12794 C CA  . PRO E 1 7   ? 59.598  -21.107 54.802  1.00 28.06  ? 7   PRO E CA  1 
ATOM   12795 C C   . PRO E 1 7   ? 61.070  -20.724 54.944  1.00 31.82  ? 7   PRO E C   1 
ATOM   12796 O O   . PRO E 1 7   ? 61.848  -21.374 55.637  1.00 32.19  ? 7   PRO E O   1 
ATOM   12797 C CB  . PRO E 1 7   ? 59.332  -22.512 55.392  1.00 29.95  ? 7   PRO E CB  1 
ATOM   12798 C CG  . PRO E 1 7   ? 58.784  -23.366 54.247  1.00 30.45  ? 7   PRO E CG  1 
ATOM   12799 C CD  . PRO E 1 7   ? 59.154  -22.646 52.978  1.00 31.27  ? 7   PRO E CD  1 
ATOM   12800 N N   . ASN E 1 8   ? 61.457  -19.642 54.267  1.00 33.29  ? 8   ASN E N   1 
ATOM   12801 C CA  . ASN E 1 8   ? 62.853  -19.234 54.256  1.00 33.04  ? 8   ASN E CA  1 
ATOM   12802 C C   . ASN E 1 8   ? 63.226  -18.657 55.618  1.00 40.59  ? 8   ASN E C   1 
ATOM   12803 O O   . ASN E 1 8   ? 63.495  -17.459 55.741  1.00 35.52  ? 8   ASN E O   1 
ATOM   12804 C CB  . ASN E 1 8   ? 63.116  -18.244 53.116  1.00 30.12  ? 8   ASN E CB  1 
ATOM   12805 C CG  . ASN E 1 8   ? 62.233  -16.987 53.179  1.00 30.31  ? 8   ASN E CG  1 
ATOM   12806 O OD1 . ASN E 1 8   ? 61.047  -17.043 53.546  1.00 27.35  ? 8   ASN E OD1 1 
ATOM   12807 N ND2 . ASN E 1 8   ? 62.805  -15.849 52.772  1.00 23.03  ? 8   ASN E ND2 1 
ATOM   12808 N N   . PHE E 1 9   ? 63.232  -19.524 56.639  1.00 38.06  ? 9   PHE E N   1 
ATOM   12809 C CA  . PHE E 1 9   ? 63.518  -19.120 58.016  1.00 44.45  ? 9   PHE E CA  1 
ATOM   12810 C C   . PHE E 1 9   ? 64.820  -18.343 58.103  1.00 44.48  ? 9   PHE E C   1 
ATOM   12811 O O   . PHE E 1 9   ? 64.837  -17.155 58.450  1.00 44.28  ? 9   PHE E O   1 
ATOM   12812 C CB  . PHE E 1 9   ? 63.597  -20.361 58.917  1.00 44.94  ? 9   PHE E CB  1 
ATOM   12813 C CG  . PHE E 1 9   ? 62.301  -20.738 59.561  1.00 44.14  ? 9   PHE E CG  1 
ATOM   12814 C CD1 . PHE E 1 9   ? 61.096  -20.533 58.914  1.00 42.05  ? 9   PHE E CD1 1 
ATOM   12815 C CD2 . PHE E 1 9   ? 62.294  -21.331 60.818  1.00 51.83  ? 9   PHE E CD2 1 
ATOM   12816 C CE1 . PHE E 1 9   ? 59.901  -20.893 59.518  1.00 45.95  ? 9   PHE E CE1 1 
ATOM   12817 C CE2 . PHE E 1 9   ? 61.112  -21.697 61.429  1.00 51.54  ? 9   PHE E CE2 1 
ATOM   12818 C CZ  . PHE E 1 9   ? 59.909  -21.477 60.779  1.00 53.91  ? 9   PHE E CZ  1 
ATOM   12819 N N   . ARG E 1 10  ? 65.927  -19.018 57.791  1.00 53.96  ? 10  ARG E N   1 
ATOM   12820 C CA  . ARG E 1 10  ? 67.271  -18.454 57.909  1.00 57.57  ? 10  ARG E CA  1 
ATOM   12821 C C   . ARG E 1 10  ? 67.658  -17.733 56.620  1.00 60.25  ? 10  ARG E C   1 
ATOM   12822 O O   . ARG E 1 10  ? 68.702  -17.973 56.010  1.00 62.70  ? 10  ARG E O   1 
ATOM   12823 C CB  . ARG E 1 10  ? 68.278  -19.547 58.251  1.00 67.26  ? 10  ARG E CB  1 
ATOM   12824 C CG  . ARG E 1 10  ? 67.811  -20.555 59.292  1.00 69.00  ? 10  ARG E CG  1 
ATOM   12825 C CD  . ARG E 1 10  ? 68.007  -20.017 60.697  1.00 71.75  ? 10  ARG E CD  1 
ATOM   12826 N NE  . ARG E 1 10  ? 67.424  -20.893 61.709  1.00 81.71  ? 10  ARG E NE  1 
ATOM   12827 C CZ  . ARG E 1 10  ? 67.447  -20.646 63.012  1.00 80.21  ? 10  ARG E CZ  1 
ATOM   12828 N NH1 . ARG E 1 10  ? 68.024  -19.559 63.499  1.00 83.50  ? 10  ARG E NH1 1 
ATOM   12829 N NH2 . ARG E 1 10  ? 66.872  -21.507 63.849  1.00 70.86  ? 10  ARG E NH2 1 
ATOM   12830 N N   . ALA E 1 11  ? 66.774  -16.842 56.195  1.00 56.55  ? 11  ALA E N   1 
ATOM   12831 C CA  . ALA E 1 11  ? 67.114  -15.935 55.114  1.00 59.26  ? 11  ALA E CA  1 
ATOM   12832 C C   . ALA E 1 11  ? 67.628  -14.599 55.639  1.00 60.27  ? 11  ALA E C   1 
ATOM   12833 O O   . ALA E 1 11  ? 68.676  -14.124 55.185  1.00 52.10  ? 11  ALA E O   1 
ATOM   12834 C CB  . ALA E 1 11  ? 65.902  -15.739 54.194  1.00 47.95  ? 11  ALA E CB  1 
ATOM   12835 N N   . ASP E 1 12  ? 66.939  -14.010 56.623  1.00 63.19  ? 12  ASP E N   1 
ATOM   12836 C CA  . ASP E 1 12  ? 67.395  -12.775 57.267  1.00 55.23  ? 12  ASP E CA  1 
ATOM   12837 C C   . ASP E 1 12  ? 68.364  -13.047 58.424  1.00 60.02  ? 12  ASP E C   1 
ATOM   12838 O O   . ASP E 1 12  ? 69.120  -12.164 58.847  1.00 57.99  ? 12  ASP E O   1 
ATOM   12839 C CB  . ASP E 1 12  ? 66.195  -11.950 57.758  1.00 57.15  ? 12  ASP E CB  1 
ATOM   12840 C CG  . ASP E 1 12  ? 65.710  -12.344 59.164  1.00 58.60  ? 12  ASP E CG  1 
ATOM   12841 O OD1 . ASP E 1 12  ? 65.528  -13.557 59.439  1.00 54.77  ? 12  ASP E OD1 1 
ATOM   12842 O OD2 . ASP E 1 12  ? 65.494  -11.421 59.990  1.00 45.22  ? 12  ASP E OD2 1 
ATOM   12843 N N   . SER E 1 29  ? 68.091  -34.120 58.596  1.00 59.25  ? 29  SER E N   1 
ATOM   12844 C CA  . SER E 1 29  ? 67.729  -35.125 57.601  1.00 62.86  ? 29  SER E CA  1 
ATOM   12845 C C   . SER E 1 29  ? 66.245  -35.477 57.665  1.00 63.37  ? 29  SER E C   1 
ATOM   12846 O O   . SER E 1 29  ? 65.402  -34.735 57.142  1.00 62.69  ? 29  SER E O   1 
ATOM   12847 C CB  . SER E 1 29  ? 68.569  -36.392 57.785  1.00 63.55  ? 29  SER E CB  1 
ATOM   12848 O OG  . SER E 1 29  ? 67.904  -37.532 57.257  1.00 60.14  ? 29  SER E OG  1 
ATOM   12849 N N   . SER E 1 30  ? 65.942  -36.609 58.321  1.00 61.45  ? 30  SER E N   1 
ATOM   12850 C CA  . SER E 1 30  ? 64.585  -37.148 58.414  1.00 59.81  ? 30  SER E CA  1 
ATOM   12851 C C   . SER E 1 30  ? 63.608  -36.195 59.099  1.00 56.41  ? 30  SER E C   1 
ATOM   12852 O O   . SER E 1 30  ? 62.391  -36.428 59.031  1.00 52.91  ? 30  SER E O   1 
ATOM   12853 C CB  . SER E 1 30  ? 64.624  -38.492 59.154  1.00 60.75  ? 30  SER E CB  1 
ATOM   12854 O OG  . SER E 1 30  ? 63.316  -38.980 59.436  1.00 56.24  ? 30  SER E OG  1 
ATOM   12855 N N   . THR E 1 31  ? 64.121  -35.141 59.738  1.00 52.20  ? 31  THR E N   1 
ATOM   12856 C CA  . THR E 1 31  ? 63.316  -34.160 60.457  1.00 48.79  ? 31  THR E CA  1 
ATOM   12857 C C   . THR E 1 31  ? 62.310  -33.475 59.536  1.00 45.53  ? 31  THR E C   1 
ATOM   12858 O O   . THR E 1 31  ? 62.623  -33.172 58.383  1.00 50.31  ? 31  THR E O   1 
ATOM   12859 C CB  . THR E 1 31  ? 64.263  -33.135 61.087  1.00 48.13  ? 31  THR E CB  1 
ATOM   12860 O OG1 . THR E 1 31  ? 64.710  -33.611 62.364  1.00 51.40  ? 31  THR E OG1 1 
ATOM   12861 C CG2 . THR E 1 31  ? 63.619  -31.797 61.237  1.00 47.20  ? 31  THR E CG2 1 
ATOM   12862 N N   . ASP E 1 32  ? 61.084  -33.239 60.038  1.00 40.88  ? 32  ASP E N   1 
ATOM   12863 C CA  . ASP E 1 32  ? 60.034  -32.631 59.217  1.00 40.61  ? 32  ASP E CA  1 
ATOM   12864 C C   . ASP E 1 32  ? 59.574  -31.279 59.752  1.00 38.35  ? 32  ASP E C   1 
ATOM   12865 O O   . ASP E 1 32  ? 58.390  -30.944 59.688  1.00 37.85  ? 32  ASP E O   1 
ATOM   12866 C CB  . ASP E 1 32  ? 58.845  -33.576 59.009  1.00 38.00  ? 32  ASP E CB  1 
ATOM   12867 C CG  . ASP E 1 32  ? 58.148  -34.024 60.312  1.00 39.62  ? 32  ASP E CG  1 
ATOM   12868 O OD1 . ASP E 1 32  ? 58.577  -33.689 61.437  1.00 30.86  ? 32  ASP E OD1 1 
ATOM   12869 O OD2 . ASP E 1 32  ? 57.141  -34.763 60.180  1.00 36.41  ? 32  ASP E OD2 1 
ATOM   12870 N N   . THR E 1 33  ? 60.532  -30.448 60.186  1.00 38.15  ? 33  THR E N   1 
ATOM   12871 C CA  . THR E 1 33  ? 60.199  -29.193 60.861  1.00 37.49  ? 33  THR E CA  1 
ATOM   12872 C C   . THR E 1 33  ? 59.365  -28.266 59.987  1.00 39.15  ? 33  THR E C   1 
ATOM   12873 O O   . THR E 1 33  ? 58.533  -27.509 60.508  1.00 40.68  ? 33  THR E O   1 
ATOM   12874 C CB  . THR E 1 33  ? 61.470  -28.469 61.329  1.00 39.78  ? 33  THR E CB  1 
ATOM   12875 O OG1 . THR E 1 33  ? 62.260  -29.352 62.131  1.00 42.60  ? 33  THR E OG1 1 
ATOM   12876 C CG2 . THR E 1 33  ? 61.126  -27.263 62.188  1.00 35.69  ? 33  THR E CG2 1 
ATOM   12877 N N   . THR E 1 34  ? 59.547  -28.307 58.672  1.00 36.58  ? 34  THR E N   1 
ATOM   12878 C CA  . THR E 1 34  ? 58.833  -27.387 57.804  1.00 32.48  ? 34  THR E CA  1 
ATOM   12879 C C   . THR E 1 34  ? 57.543  -27.969 57.240  1.00 33.88  ? 34  THR E C   1 
ATOM   12880 O O   . THR E 1 34  ? 56.833  -27.272 56.505  1.00 24.44  ? 34  THR E O   1 
ATOM   12881 C CB  . THR E 1 34  ? 59.750  -26.929 56.670  1.00 38.20  ? 34  THR E CB  1 
ATOM   12882 O OG1 . THR E 1 34  ? 60.124  -28.054 55.880  1.00 41.42  ? 34  THR E OG1 1 
ATOM   12883 C CG2 . THR E 1 34  ? 61.008  -26.272 57.245  1.00 35.73  ? 34  THR E CG2 1 
ATOM   12884 N N   . ALA E 1 35  ? 57.203  -29.212 57.591  1.00 34.18  ? 35  ALA E N   1 
ATOM   12885 C CA  . ALA E 1 35  ? 55.979  -29.810 57.072  1.00 31.56  ? 35  ALA E CA  1 
ATOM   12886 C C   . ALA E 1 35  ? 54.745  -29.094 57.592  1.00 27.16  ? 35  ALA E C   1 
ATOM   12887 O O   . ALA E 1 35  ? 53.727  -29.024 56.892  1.00 25.06  ? 35  ALA E O   1 
ATOM   12888 C CB  . ALA E 1 35  ? 55.923  -31.291 57.438  1.00 40.08  ? 35  ALA E CB  1 
ATOM   12889 N N   . ARG E 1 36  ? 54.830  -28.538 58.800  1.00 24.95  ? 36  ARG E N   1 
ATOM   12890 C CA  . ARG E 1 36  ? 53.706  -27.852 59.420  1.00 27.09  ? 36  ARG E CA  1 
ATOM   12891 C C   . ARG E 1 36  ? 53.097  -26.787 58.524  1.00 28.22  ? 36  ARG E C   1 
ATOM   12892 O O   . ARG E 1 36  ? 51.922  -26.448 58.686  1.00 25.71  ? 36  ARG E O   1 
ATOM   12893 C CB  . ARG E 1 36  ? 54.162  -27.195 60.729  1.00 26.92  ? 36  ARG E CB  1 
ATOM   12894 C CG  . ARG E 1 36  ? 54.897  -25.864 60.515  1.00 28.71  ? 36  ARG E CG  1 
ATOM   12895 C CD  . ARG E 1 36  ? 56.024  -25.630 61.525  1.00 25.81  ? 36  ARG E CD  1 
ATOM   12896 N NE  . ARG E 1 36  ? 55.499  -25.381 62.859  1.00 23.78  ? 36  ARG E NE  1 
ATOM   12897 C CZ  . ARG E 1 36  ? 55.063  -24.197 63.271  1.00 32.42  ? 36  ARG E CZ  1 
ATOM   12898 N NH1 . ARG E 1 36  ? 55.128  -23.125 62.484  1.00 25.62  ? 36  ARG E NH1 1 
ATOM   12899 N NH2 . ARG E 1 36  ? 54.554  -24.083 64.500  1.00 22.99  ? 36  ARG E NH2 1 
ATOM   12900 N N   . PHE E 1 37  ? 53.867  -26.239 57.590  1.00 28.02  ? 37  PHE E N   1 
ATOM   12901 C CA  . PHE E 1 37  ? 53.358  -25.140 56.795  1.00 23.89  ? 37  PHE E CA  1 
ATOM   12902 C C   . PHE E 1 37  ? 52.446  -25.607 55.674  1.00 24.72  ? 37  PHE E C   1 
ATOM   12903 O O   . PHE E 1 37  ? 51.776  -24.772 55.056  1.00 24.39  ? 37  PHE E O   1 
ATOM   12904 C CB  . PHE E 1 37  ? 54.540  -24.321 56.271  1.00 27.89  ? 37  PHE E CB  1 
ATOM   12905 C CG  . PHE E 1 37  ? 55.369  -23.711 57.375  1.00 24.83  ? 37  PHE E CG  1 
ATOM   12906 C CD1 . PHE E 1 37  ? 54.860  -22.693 58.159  1.00 24.42  ? 37  PHE E CD1 1 
ATOM   12907 C CD2 . PHE E 1 37  ? 56.635  -24.191 57.658  1.00 27.00  ? 37  PHE E CD2 1 
ATOM   12908 C CE1 . PHE E 1 37  ? 55.611  -22.151 59.194  1.00 23.66  ? 37  PHE E CE1 1 
ATOM   12909 C CE2 . PHE E 1 37  ? 57.400  -23.644 58.685  1.00 28.10  ? 37  PHE E CE2 1 
ATOM   12910 C CZ  . PHE E 1 37  ? 56.882  -22.625 59.452  1.00 25.12  ? 37  PHE E CZ  1 
ATOM   12911 N N   . LEU E 1 38  ? 52.373  -26.921 55.421  1.00 29.73  ? 38  LEU E N   1 
ATOM   12912 C CA  . LEU E 1 38  ? 51.316  -27.451 54.560  1.00 26.67  ? 38  LEU E CA  1 
ATOM   12913 C C   . LEU E 1 38  ? 49.936  -26.958 54.992  1.00 25.91  ? 38  LEU E C   1 
ATOM   12914 O O   . LEU E 1 38  ? 49.054  -26.754 54.151  1.00 23.79  ? 38  LEU E O   1 
ATOM   12915 C CB  . LEU E 1 38  ? 51.341  -28.989 54.569  1.00 33.50  ? 38  LEU E CB  1 
ATOM   12916 C CG  . LEU E 1 38  ? 52.015  -29.746 53.417  1.00 34.26  ? 38  LEU E CG  1 
ATOM   12917 C CD1 . LEU E 1 38  ? 51.921  -31.248 53.650  1.00 34.41  ? 38  LEU E CD1 1 
ATOM   12918 C CD2 . LEU E 1 38  ? 51.448  -29.383 52.035  1.00 33.25  ? 38  LEU E CD2 1 
ATOM   12919 N N   . TRP E 1 39  ? 49.731  -26.736 56.294  1.00 22.29  ? 39  TRP E N   1 
ATOM   12920 C CA  . TRP E 1 39  ? 48.419  -26.297 56.743  1.00 24.64  ? 39  TRP E CA  1 
ATOM   12921 C C   . TRP E 1 39  ? 48.014  -24.929 56.172  1.00 23.94  ? 39  TRP E C   1 
ATOM   12922 O O   . TRP E 1 39  ? 46.837  -24.565 56.259  1.00 24.09  ? 39  TRP E O   1 
ATOM   12923 C CB  . TRP E 1 39  ? 48.392  -26.323 58.267  1.00 22.03  ? 39  TRP E CB  1 
ATOM   12924 C CG  . TRP E 1 39  ? 48.305  -27.733 58.823  1.00 29.03  ? 39  TRP E CG  1 
ATOM   12925 C CD1 . TRP E 1 39  ? 49.350  -28.534 59.212  1.00 28.56  ? 39  TRP E CD1 1 
ATOM   12926 C CD2 . TRP E 1 39  ? 47.113  -28.507 59.037  1.00 21.97  ? 39  TRP E CD2 1 
ATOM   12927 N NE1 . TRP E 1 39  ? 48.876  -29.742 59.669  1.00 28.65  ? 39  TRP E NE1 1 
ATOM   12928 C CE2 . TRP E 1 39  ? 47.509  -29.751 59.564  1.00 25.97  ? 39  TRP E CE2 1 
ATOM   12929 C CE3 . TRP E 1 39  ? 45.751  -28.266 58.830  1.00 30.05  ? 39  TRP E CE3 1 
ATOM   12930 C CZ2 . TRP E 1 39  ? 46.591  -30.756 59.890  1.00 26.94  ? 39  TRP E CZ2 1 
ATOM   12931 C CZ3 . TRP E 1 39  ? 44.837  -29.263 59.160  1.00 29.41  ? 39  TRP E CZ3 1 
ATOM   12932 C CH2 . TRP E 1 39  ? 45.267  -30.496 59.685  1.00 25.49  ? 39  TRP E CH2 1 
ATOM   12933 N N   . HIS E 1 40  ? 48.943  -24.198 55.545  1.00 21.97  ? 40  HIS E N   1 
ATOM   12934 C CA  . HIS E 1 40  ? 48.637  -23.010 54.757  1.00 21.08  ? 40  HIS E CA  1 
ATOM   12935 C C   . HIS E 1 40  ? 48.085  -23.329 53.363  1.00 28.03  ? 40  HIS E C   1 
ATOM   12936 O O   . HIS E 1 40  ? 47.604  -22.409 52.689  1.00 25.88  ? 40  HIS E O   1 
ATOM   12937 C CB  . HIS E 1 40  ? 49.893  -22.153 54.554  1.00 24.89  ? 40  HIS E CB  1 
ATOM   12938 C CG  . HIS E 1 40  ? 50.365  -21.417 55.774  1.00 28.28  ? 40  HIS E CG  1 
ATOM   12939 N ND1 . HIS E 1 40  ? 49.726  -20.297 56.262  1.00 20.67  ? 40  HIS E ND1 1 
ATOM   12940 C CD2 . HIS E 1 40  ? 51.452  -21.607 56.569  1.00 23.67  ? 40  HIS E CD2 1 
ATOM   12941 C CE1 . HIS E 1 40  ? 50.381  -19.840 57.318  1.00 18.82  ? 40  HIS E CE1 1 
ATOM   12942 N NE2 . HIS E 1 40  ? 51.435  -20.612 57.522  1.00 21.23  ? 40  HIS E NE2 1 
ATOM   12943 N N   . ALA E 1 41  ? 48.155  -24.583 52.901  1.00 22.03  ? 41  ALA E N   1 
ATOM   12944 C CA  . ALA E 1 41  ? 47.853  -24.885 51.500  1.00 29.57  ? 41  ALA E CA  1 
ATOM   12945 C C   . ALA E 1 41  ? 46.366  -24.775 51.166  1.00 27.44  ? 41  ALA E C   1 
ATOM   12946 O O   . ALA E 1 41  ? 45.506  -25.266 51.901  1.00 27.61  ? 41  ALA E O   1 
ATOM   12947 C CB  . ALA E 1 41  ? 48.335  -26.290 51.133  1.00 24.28  ? 41  ALA E CB  1 
ATOM   12948 N N   . GLU E 1 42  ? 46.082  -24.127 50.040  1.00 31.35  ? 42  GLU E N   1 
ATOM   12949 C CA  . GLU E 1 42  ? 44.831  -24.190 49.298  1.00 34.95  ? 42  GLU E CA  1 
ATOM   12950 C C   . GLU E 1 42  ? 45.090  -24.912 47.979  1.00 41.06  ? 42  GLU E C   1 
ATOM   12951 O O   . GLU E 1 42  ? 46.240  -25.201 47.630  1.00 37.37  ? 42  GLU E O   1 
ATOM   12952 C CB  . GLU E 1 42  ? 44.280  -22.784 49.022  1.00 37.56  ? 42  GLU E CB  1 
ATOM   12953 C CG  . GLU E 1 42  ? 43.378  -22.194 50.107  1.00 40.75  ? 42  GLU E CG  1 
ATOM   12954 C CD  . GLU E 1 42  ? 43.613  -20.699 50.289  1.00 52.00  ? 42  GLU E CD  1 
ATOM   12955 O OE1 . GLU E 1 42  ? 42.689  -19.998 50.757  1.00 58.69  ? 42  GLU E OE1 1 
ATOM   12956 O OE2 . GLU E 1 42  ? 44.729  -20.225 49.967  1.00 52.34  ? 42  GLU E OE2 1 
ATOM   12957 N N   . ASP E 1 43  ? 44.013  -25.183 47.231  1.00 38.70  ? 43  ASP E N   1 
ATOM   12958 C CA  . ASP E 1 43  ? 44.141  -25.830 45.923  1.00 36.96  ? 43  ASP E CA  1 
ATOM   12959 C C   . ASP E 1 43  ? 45.157  -25.101 45.038  1.00 41.66  ? 43  ASP E C   1 
ATOM   12960 O O   . ASP E 1 43  ? 45.109  -23.875 44.888  1.00 43.84  ? 43  ASP E O   1 
ATOM   12961 C CB  . ASP E 1 43  ? 42.783  -25.863 45.217  1.00 39.70  ? 43  ASP E CB  1 
ATOM   12962 C CG  . ASP E 1 43  ? 41.906  -27.022 45.649  1.00 44.20  ? 43  ASP E CG  1 
ATOM   12963 O OD1 . ASP E 1 43  ? 42.199  -27.653 46.689  1.00 45.96  ? 43  ASP E OD1 1 
ATOM   12964 O OD2 . ASP E 1 43  ? 40.906  -27.295 44.941  1.00 41.90  ? 43  ASP E OD2 1 
ATOM   12965 N N   . GLY E 1 44  ? 46.077  -25.860 44.442  1.00 34.41  ? 44  GLY E N   1 
ATOM   12966 C CA  . GLY E 1 44  ? 47.035  -25.318 43.502  1.00 35.23  ? 44  GLY E CA  1 
ATOM   12967 C C   . GLY E 1 44  ? 48.381  -24.963 44.098  1.00 39.70  ? 44  GLY E C   1 
ATOM   12968 O O   . GLY E 1 44  ? 49.348  -24.775 43.346  1.00 41.65  ? 44  GLY E O   1 
ATOM   12969 N N   . ASP E 1 45  ? 48.472  -24.884 45.422  1.00 34.80  ? 45  ASP E N   1 
ATOM   12970 C CA  . ASP E 1 45  ? 49.645  -24.319 46.061  1.00 37.92  ? 45  ASP E CA  1 
ATOM   12971 C C   . ASP E 1 45  ? 50.858  -25.230 45.911  1.00 36.10  ? 45  ASP E C   1 
ATOM   12972 O O   . ASP E 1 45  ? 50.759  -26.424 45.612  1.00 35.24  ? 45  ASP E O   1 
ATOM   12973 C CB  . ASP E 1 45  ? 49.370  -24.053 47.541  1.00 33.73  ? 45  ASP E CB  1 
ATOM   12974 C CG  . ASP E 1 45  ? 48.552  -22.793 47.762  1.00 33.48  ? 45  ASP E CG  1 
ATOM   12975 O OD1 . ASP E 1 45  ? 48.275  -22.076 46.777  1.00 35.85  ? 45  ASP E OD1 1 
ATOM   12976 O OD2 . ASP E 1 45  ? 48.173  -22.526 48.921  1.00 33.99  ? 45  ASP E OD2 1 
ATOM   12977 N N   . VAL E 1 46  ? 52.020  -24.629 46.123  1.00 36.07  ? 46  VAL E N   1 
ATOM   12978 C CA  . VAL E 1 46  ? 53.299  -25.321 46.183  1.00 34.50  ? 46  VAL E CA  1 
ATOM   12979 C C   . VAL E 1 46  ? 53.924  -25.052 47.540  1.00 31.06  ? 46  VAL E C   1 
ATOM   12980 O O   . VAL E 1 46  ? 53.936  -23.910 48.011  1.00 33.41  ? 46  VAL E O   1 
ATOM   12981 C CB  . VAL E 1 46  ? 54.237  -24.842 45.060  1.00 39.96  ? 46  VAL E CB  1 
ATOM   12982 C CG1 . VAL E 1 46  ? 55.566  -25.595 45.107  1.00 36.12  ? 46  VAL E CG1 1 
ATOM   12983 C CG2 . VAL E 1 46  ? 53.534  -24.946 43.702  1.00 38.18  ? 46  VAL E CG2 1 
ATOM   12984 N N   . LEU E 1 47  ? 54.457  -26.088 48.165  1.00 35.62  ? 47  LEU E N   1 
ATOM   12985 C CA  . LEU E 1 47  ? 55.224  -25.929 49.392  1.00 32.28  ? 47  LEU E CA  1 
ATOM   12986 C C   . LEU E 1 47  ? 56.661  -26.344 49.134  1.00 39.30  ? 47  LEU E C   1 
ATOM   12987 O O   . LEU E 1 47  ? 56.915  -27.472 48.695  1.00 34.52  ? 47  LEU E O   1 
ATOM   12988 C CB  . LEU E 1 47  ? 54.639  -26.755 50.530  1.00 31.95  ? 47  LEU E CB  1 
ATOM   12989 C CG  . LEU E 1 47  ? 55.583  -26.829 51.722  1.00 32.67  ? 47  LEU E CG  1 
ATOM   12990 C CD1 . LEU E 1 47  ? 55.765  -25.448 52.358  1.00 31.52  ? 47  LEU E CD1 1 
ATOM   12991 C CD2 . LEU E 1 47  ? 55.067  -27.827 52.725  1.00 33.40  ? 47  LEU E CD2 1 
ATOM   12992 N N   . VAL E 1 48  ? 57.594  -25.438 49.424  1.00 37.03  ? 48  VAL E N   1 
ATOM   12993 C CA  . VAL E 1 48  ? 59.019  -25.694 49.281  1.00 39.04  ? 48  VAL E CA  1 
ATOM   12994 C C   . VAL E 1 48  ? 59.559  -25.993 50.669  1.00 40.93  ? 48  VAL E C   1 
ATOM   12995 O O   . VAL E 1 48  ? 59.224  -25.293 51.625  1.00 46.06  ? 48  VAL E O   1 
ATOM   12996 C CB  . VAL E 1 48  ? 59.739  -24.495 48.638  1.00 33.32  ? 48  VAL E CB  1 
ATOM   12997 C CG1 . VAL E 1 48  ? 61.146  -24.887 48.216  1.00 30.42  ? 48  VAL E CG1 1 
ATOM   12998 C CG2 . VAL E 1 48  ? 58.946  -23.979 47.439  1.00 33.30  ? 48  VAL E CG2 1 
ATOM   12999 N N   . ILE E 1 49  ? 60.359  -27.045 50.798  1.00 43.15  ? 49  ILE E N   1 
ATOM   13000 C CA  . ILE E 1 49  ? 60.822  -27.478 52.119  1.00 45.74  ? 49  ILE E CA  1 
ATOM   13001 C C   . ILE E 1 49  ? 62.285  -27.906 52.114  1.00 46.93  ? 49  ILE E C   1 
ATOM   13002 O O   . ILE E 1 49  ? 62.730  -28.610 51.199  1.00 46.09  ? 49  ILE E O   1 
ATOM   13003 C CB  . ILE E 1 49  ? 59.934  -28.610 52.658  1.00 44.87  ? 49  ILE E CB  1 
ATOM   13004 C CG1 . ILE E 1 49  ? 59.950  -29.770 51.674  1.00 47.02  ? 49  ILE E CG1 1 
ATOM   13005 C CG2 . ILE E 1 49  ? 58.531  -28.135 52.985  1.00 45.62  ? 49  ILE E CG2 1 
ATOM   13006 C CD1 . ILE E 1 49  ? 59.792  -31.094 52.296  1.00 50.43  ? 49  ILE E CD1 1 
ATOM   13007 N N   . PRO E 1 50  ? 63.063  -27.520 53.126  1.00 46.81  ? 50  PRO E N   1 
ATOM   13008 C CA  . PRO E 1 50  ? 64.455  -27.980 53.200  1.00 49.00  ? 50  PRO E CA  1 
ATOM   13009 C C   . PRO E 1 50  ? 64.593  -29.429 53.625  1.00 49.24  ? 50  PRO E C   1 
ATOM   13010 O O   . PRO E 1 50  ? 65.705  -29.969 53.544  1.00 50.81  ? 50  PRO E O   1 
ATOM   13011 C CB  . PRO E 1 50  ? 65.075  -27.051 54.254  1.00 48.06  ? 50  PRO E CB  1 
ATOM   13012 C CG  . PRO E 1 50  ? 63.935  -26.692 55.145  1.00 45.49  ? 50  PRO E CG  1 
ATOM   13013 C CD  . PRO E 1 50  ? 62.720  -26.610 54.232  1.00 45.67  ? 50  PRO E CD  1 
ATOM   13014 N N   . ASP E 1 51  ? 63.518  -30.071 54.078  1.00 49.28  ? 51  ASP E N   1 
ATOM   13015 C CA  . ASP E 1 51  ? 63.625  -31.370 54.728  1.00 51.94  ? 51  ASP E CA  1 
ATOM   13016 C C   . ASP E 1 51  ? 62.370  -32.198 54.478  1.00 50.17  ? 51  ASP E C   1 
ATOM   13017 O O   . ASP E 1 51  ? 61.258  -31.735 54.728  1.00 60.32  ? 51  ASP E O   1 
ATOM   13018 C CB  . ASP E 1 51  ? 63.870  -31.184 56.234  1.00 52.10  ? 51  ASP E CB  1 
ATOM   13019 C CG  . ASP E 1 51  ? 63.064  -30.035 56.827  1.00 52.47  ? 51  ASP E CG  1 
ATOM   13020 O OD1 . ASP E 1 51  ? 63.677  -29.112 57.407  1.00 60.33  ? 51  ASP E OD1 1 
ATOM   13021 O OD2 . ASP E 1 51  ? 61.820  -30.045 56.727  1.00 54.88  ? 51  ASP E OD2 1 
ATOM   13022 N N   . THR E 1 52  ? 62.561  -33.452 54.088  1.00 51.89  ? 52  THR E N   1 
ATOM   13023 C CA  . THR E 1 52  ? 61.485  -34.298 53.579  1.00 57.11  ? 52  THR E CA  1 
ATOM   13024 C C   . THR E 1 52  ? 60.361  -34.540 54.593  1.00 55.93  ? 52  THR E C   1 
ATOM   13025 O O   . THR E 1 52  ? 60.601  -34.721 55.789  1.00 57.68  ? 52  THR E O   1 
ATOM   13026 C CB  . THR E 1 52  ? 62.077  -35.639 53.148  1.00 60.78  ? 52  THR E CB  1 
ATOM   13027 O OG1 . THR E 1 52  ? 62.091  -36.535 54.270  1.00 65.57  ? 52  THR E OG1 1 
ATOM   13028 C CG2 . THR E 1 52  ? 63.503  -35.444 52.642  1.00 62.58  ? 52  THR E CG2 1 
ATOM   13029 N N   . VAL E 1 53  ? 59.125  -34.602 54.091  1.00 52.86  ? 53  VAL E N   1 
ATOM   13030 C CA  . VAL E 1 53  ? 57.929  -34.840 54.897  1.00 50.58  ? 53  VAL E CA  1 
ATOM   13031 C C   . VAL E 1 53  ? 57.415  -36.257 54.675  1.00 43.50  ? 53  VAL E C   1 
ATOM   13032 O O   . VAL E 1 53  ? 57.630  -36.857 53.618  1.00 43.83  ? 53  VAL E O   1 
ATOM   13033 C CB  . VAL E 1 53  ? 56.827  -33.820 54.555  1.00 46.44  ? 53  VAL E CB  1 
ATOM   13034 C CG1 . VAL E 1 53  ? 57.418  -32.421 54.525  1.00 48.16  ? 53  VAL E CG1 1 
ATOM   13035 C CG2 . VAL E 1 53  ? 56.191  -34.166 53.219  1.00 45.01  ? 53  VAL E CG2 1 
ATOM   13036 N N   . ASP E 1 54  ? 56.723  -36.787 55.687  1.00 44.45  ? 54  ASP E N   1 
ATOM   13037 C CA  . ASP E 1 54  ? 56.044  -38.076 55.615  1.00 38.83  ? 54  ASP E CA  1 
ATOM   13038 C C   . ASP E 1 54  ? 55.200  -38.151 54.347  1.00 35.30  ? 54  ASP E C   1 
ATOM   13039 O O   . ASP E 1 54  ? 54.344  -37.282 54.134  1.00 42.91  ? 54  ASP E O   1 
ATOM   13040 C CB  . ASP E 1 54  ? 55.142  -38.256 56.835  1.00 42.88  ? 54  ASP E CB  1 
ATOM   13041 C CG  . ASP E 1 54  ? 54.571  -39.680 56.962  1.00 44.71  ? 54  ASP E CG  1 
ATOM   13042 O OD1 . ASP E 1 54  ? 53.945  -40.180 55.991  1.00 43.13  ? 54  ASP E OD1 1 
ATOM   13043 O OD2 . ASP E 1 54  ? 54.696  -40.271 58.070  1.00 39.09  ? 54  ASP E OD2 1 
ATOM   13044 N N   . PRO E 1 55  ? 55.402  -39.152 53.491  1.00 42.10  ? 55  PRO E N   1 
ATOM   13045 C CA  . PRO E 1 55  ? 54.622  -39.216 52.240  1.00 40.69  ? 55  PRO E CA  1 
ATOM   13046 C C   . PRO E 1 55  ? 53.115  -39.212 52.448  1.00 39.82  ? 55  PRO E C   1 
ATOM   13047 O O   . PRO E 1 55  ? 52.381  -38.816 51.529  1.00 39.64  ? 55  PRO E O   1 
ATOM   13048 C CB  . PRO E 1 55  ? 55.099  -40.527 51.599  1.00 38.52  ? 55  PRO E CB  1 
ATOM   13049 C CG  . PRO E 1 55  ? 56.474  -40.723 52.148  1.00 36.75  ? 55  PRO E CG  1 
ATOM   13050 C CD  . PRO E 1 55  ? 56.415  -40.218 53.567  1.00 39.21  ? 55  PRO E CD  1 
ATOM   13051 N N   . ASP E 1 56  ? 52.634  -39.621 53.630  1.00 37.16  ? 56  ASP E N   1 
ATOM   13052 C CA  . ASP E 1 56  ? 51.203  -39.565 53.933  1.00 35.56  ? 56  ASP E CA  1 
ATOM   13053 C C   . ASP E 1 56  ? 50.735  -38.142 54.246  1.00 39.27  ? 56  ASP E C   1 
ATOM   13054 O O   . ASP E 1 56  ? 49.556  -37.818 54.043  1.00 36.94  ? 56  ASP E O   1 
ATOM   13055 C CB  . ASP E 1 56  ? 50.894  -40.502 55.110  1.00 36.89  ? 56  ASP E CB  1 
ATOM   13056 C CG  . ASP E 1 56  ? 51.027  -41.981 54.738  1.00 41.52  ? 56  ASP E CG  1 
ATOM   13057 O OD1 . ASP E 1 56  ? 50.048  -42.562 54.225  1.00 33.31  ? 56  ASP E OD1 1 
ATOM   13058 O OD2 . ASP E 1 56  ? 52.124  -42.559 54.930  1.00 44.83  ? 56  ASP E OD2 1 
ATOM   13059 N N   . PHE E 1 57  ? 51.642  -37.271 54.708  1.00 40.87  ? 57  PHE E N   1 
ATOM   13060 C CA  . PHE E 1 57  ? 51.220  -35.988 55.273  1.00 37.09  ? 57  PHE E CA  1 
ATOM   13061 C C   . PHE E 1 57  ? 50.381  -35.155 54.320  1.00 32.08  ? 57  PHE E C   1 
ATOM   13062 O O   . PHE E 1 57  ? 49.276  -34.747 54.717  1.00 33.77  ? 57  PHE E O   1 
ATOM   13063 C CB  . PHE E 1 57  ? 52.441  -35.207 55.773  1.00 35.71  ? 57  PHE E CB  1 
ATOM   13064 C CG  . PHE E 1 57  ? 52.136  -34.293 56.916  1.00 40.50  ? 57  PHE E CG  1 
ATOM   13065 C CD1 . PHE E 1 57  ? 51.785  -34.809 58.154  1.00 40.98  ? 57  PHE E CD1 1 
ATOM   13066 C CD2 . PHE E 1 57  ? 52.186  -32.917 56.759  1.00 42.38  ? 57  PHE E CD2 1 
ATOM   13067 C CE1 . PHE E 1 57  ? 51.486  -33.974 59.221  1.00 33.15  ? 57  PHE E CE1 1 
ATOM   13068 C CE2 . PHE E 1 57  ? 51.897  -32.076 57.824  1.00 40.84  ? 57  PHE E CE2 1 
ATOM   13069 C CZ  . PHE E 1 57  ? 51.542  -32.615 59.062  1.00 35.99  ? 57  PHE E CZ  1 
ATOM   13070 N N   . PRO E 1 58  ? 50.817  -34.847 53.089  1.00 35.94  ? 58  PRO E N   1 
ATOM   13071 C CA  . PRO E 1 58  ? 49.975  -34.001 52.221  1.00 36.63  ? 58  PRO E CA  1 
ATOM   13072 C C   . PRO E 1 58  ? 48.508  -34.420 52.176  1.00 36.15  ? 58  PRO E C   1 
ATOM   13073 O O   . PRO E 1 58  ? 47.612  -33.578 52.346  1.00 31.81  ? 58  PRO E O   1 
ATOM   13074 C CB  . PRO E 1 58  ? 50.663  -34.136 50.859  1.00 36.87  ? 58  PRO E CB  1 
ATOM   13075 C CG  . PRO E 1 58  ? 52.103  -34.334 51.210  1.00 37.42  ? 58  PRO E CG  1 
ATOM   13076 C CD  . PRO E 1 58  ? 52.137  -35.113 52.473  1.00 34.22  ? 58  PRO E CD  1 
ATOM   13077 N N   . GLY E 1 59  ? 48.241  -35.715 51.993  1.00 35.51  ? 59  GLY E N   1 
ATOM   13078 C CA  . GLY E 1 59  ? 46.866  -36.172 51.930  1.00 32.36  ? 59  GLY E CA  1 
ATOM   13079 C C   . GLY E 1 59  ? 46.143  -36.090 53.254  1.00 29.91  ? 59  GLY E C   1 
ATOM   13080 O O   . GLY E 1 59  ? 44.944  -35.803 53.287  1.00 31.29  ? 59  GLY E O   1 
ATOM   13081 N N   . TYR E 1 60  ? 46.848  -36.335 54.361  1.00 28.10  ? 60  TYR E N   1 
ATOM   13082 C CA  . TYR E 1 60  ? 46.215  -36.198 55.668  1.00 32.31  ? 60  TYR E CA  1 
ATOM   13083 C C   . TYR E 1 60  ? 45.783  -34.754 55.926  1.00 32.32  ? 60  TYR E C   1 
ATOM   13084 O O   . TYR E 1 60  ? 44.706  -34.505 56.484  1.00 29.67  ? 60  TYR E O   1 
ATOM   13085 C CB  . TYR E 1 60  ? 47.157  -36.703 56.765  1.00 32.24  ? 60  TYR E CB  1 
ATOM   13086 C CG  . TYR E 1 60  ? 46.865  -36.147 58.148  1.00 26.64  ? 60  TYR E CG  1 
ATOM   13087 C CD1 . TYR E 1 60  ? 45.805  -36.640 58.909  1.00 27.87  ? 60  TYR E CD1 1 
ATOM   13088 C CD2 . TYR E 1 60  ? 47.657  -35.133 58.697  1.00 28.26  ? 60  TYR E CD2 1 
ATOM   13089 C CE1 . TYR E 1 60  ? 45.531  -36.140 60.186  1.00 26.85  ? 60  TYR E CE1 1 
ATOM   13090 C CE2 . TYR E 1 60  ? 47.399  -34.628 59.971  1.00 27.91  ? 60  TYR E CE2 1 
ATOM   13091 C CZ  . TYR E 1 60  ? 46.335  -35.139 60.711  1.00 27.28  ? 60  TYR E CZ  1 
ATOM   13092 O OH  . TYR E 1 60  ? 46.072  -34.646 61.960  1.00 23.27  ? 60  TYR E OH  1 
ATOM   13093 N N   . VAL E 1 61  ? 46.587  -33.784 55.497  1.00 33.76  ? 61  VAL E N   1 
ATOM   13094 C CA  . VAL E 1 61  ? 46.221  -32.394 55.741  1.00 31.04  ? 61  VAL E CA  1 
ATOM   13095 C C   . VAL E 1 61  ? 45.048  -31.991 54.861  1.00 31.95  ? 61  VAL E C   1 
ATOM   13096 O O   . VAL E 1 61  ? 44.109  -31.337 55.325  1.00 31.51  ? 61  VAL E O   1 
ATOM   13097 C CB  . VAL E 1 61  ? 47.439  -31.479 55.540  1.00 31.51  ? 61  VAL E CB  1 
ATOM   13098 C CG1 . VAL E 1 61  ? 46.988  -30.048 55.281  1.00 33.24  ? 61  VAL E CG1 1 
ATOM   13099 C CG2 . VAL E 1 61  ? 48.345  -31.550 56.771  1.00 28.46  ? 61  VAL E CG2 1 
ATOM   13100 N N   . ALA E 1 62  ? 45.055  -32.407 53.590  1.00 35.38  ? 62  ALA E N   1 
ATOM   13101 C CA  . ALA E 1 62  ? 43.950  -32.056 52.692  1.00 31.64  ? 62  ALA E CA  1 
ATOM   13102 C C   . ALA E 1 62  ? 42.626  -32.671 53.144  1.00 31.78  ? 62  ALA E C   1 
ATOM   13103 O O   . ALA E 1 62  ? 41.575  -32.025 53.057  1.00 36.63  ? 62  ALA E O   1 
ATOM   13104 C CB  . ALA E 1 62  ? 44.280  -32.499 51.274  1.00 37.26  ? 62  ALA E CB  1 
ATOM   13105 N N   . ASP E 1 63  ? 42.658  -33.928 53.610  1.00 32.63  ? 63  ASP E N   1 
ATOM   13106 C CA  . ASP E 1 63  ? 41.463  -34.577 54.164  1.00 36.90  ? 63  ASP E CA  1 
ATOM   13107 C C   . ASP E 1 63  ? 40.893  -33.803 55.351  1.00 38.15  ? 63  ASP E C   1 
ATOM   13108 O O   . ASP E 1 63  ? 39.671  -33.765 55.554  1.00 38.64  ? 63  ASP E O   1 
ATOM   13109 C CB  . ASP E 1 63  ? 41.783  -36.010 54.612  1.00 35.95  ? 63  ASP E CB  1 
ATOM   13110 C CG  . ASP E 1 63  ? 41.934  -36.985 53.448  1.00 34.70  ? 63  ASP E CG  1 
ATOM   13111 O OD1 . ASP E 1 63  ? 41.359  -36.728 52.376  1.00 37.10  ? 63  ASP E OD1 1 
ATOM   13112 O OD2 . ASP E 1 63  ? 42.624  -38.016 53.615  1.00 34.85  ? 63  ASP E OD2 1 
ATOM   13113 N N   . THR E 1 64  ? 41.764  -33.216 56.168  1.00 35.18  ? 64  THR E N   1 
ATOM   13114 C CA  . THR E 1 64  ? 41.297  -32.512 57.352  1.00 32.75  ? 64  THR E CA  1 
ATOM   13115 C C   . THR E 1 64  ? 40.760  -31.128 57.013  1.00 33.93  ? 64  THR E C   1 
ATOM   13116 O O   . THR E 1 64  ? 39.780  -30.675 57.618  1.00 35.98  ? 64  THR E O   1 
ATOM   13117 C CB  . THR E 1 64  ? 42.430  -32.427 58.361  1.00 32.14  ? 64  THR E CB  1 
ATOM   13118 O OG1 . THR E 1 64  ? 42.921  -33.753 58.607  1.00 31.30  ? 64  THR E OG1 1 
ATOM   13119 C CG2 . THR E 1 64  ? 41.942  -31.792 59.647  1.00 29.62  ? 64  THR E CG2 1 
ATOM   13120 N N   . LEU E 1 65  ? 41.385  -30.451 56.053  1.00 28.48  ? 65  LEU E N   1 
ATOM   13121 C CA  . LEU E 1 65  ? 40.946  -29.146 55.602  1.00 28.67  ? 65  LEU E CA  1 
ATOM   13122 C C   . LEU E 1 65  ? 39.899  -29.202 54.501  1.00 38.66  ? 65  LEU E C   1 
ATOM   13123 O O   . LEU E 1 65  ? 39.304  -28.165 54.187  1.00 37.90  ? 65  LEU E O   1 
ATOM   13124 C CB  . LEU E 1 65  ? 42.138  -28.364 55.083  1.00 33.18  ? 65  LEU E CB  1 
ATOM   13125 C CG  . LEU E 1 65  ? 43.090  -27.982 56.203  1.00 38.48  ? 65  LEU E CG  1 
ATOM   13126 C CD1 . LEU E 1 65  ? 44.348  -27.422 55.570  1.00 31.63  ? 65  LEU E CD1 1 
ATOM   13127 C CD2 . LEU E 1 65  ? 42.400  -26.974 57.162  1.00 24.57  ? 65  LEU E CD2 1 
ATOM   13128 N N   . GLY E 1 66  ? 39.688  -30.366 53.884  1.00 38.29  ? 66  GLY E N   1 
ATOM   13129 C CA  . GLY E 1 66  ? 38.717  -30.495 52.816  1.00 32.81  ? 66  GLY E CA  1 
ATOM   13130 C C   . GLY E 1 66  ? 39.159  -29.829 51.529  1.00 39.05  ? 66  GLY E C   1 
ATOM   13131 O O   . GLY E 1 66  ? 38.456  -28.960 51.010  1.00 45.49  ? 66  GLY E O   1 
ATOM   13132 N N   . ILE E 1 67  ? 40.319  -30.215 50.999  1.00 39.94  ? 67  ILE E N   1 
ATOM   13133 C CA  . ILE E 1 67  ? 40.837  -29.626 49.772  1.00 42.10  ? 67  ILE E CA  1 
ATOM   13134 C C   . ILE E 1 67  ? 41.440  -30.723 48.899  1.00 42.06  ? 67  ILE E C   1 
ATOM   13135 O O   . ILE E 1 67  ? 41.881  -31.765 49.389  1.00 42.68  ? 67  ILE E O   1 
ATOM   13136 C CB  . ILE E 1 67  ? 41.879  -28.502 50.046  1.00 44.41  ? 67  ILE E CB  1 
ATOM   13137 C CG1 . ILE E 1 67  ? 43.043  -29.024 50.888  1.00 42.45  ? 67  ILE E CG1 1 
ATOM   13138 C CG2 . ILE E 1 67  ? 41.223  -27.258 50.683  1.00 39.21  ? 67  ILE E CG2 1 
ATOM   13139 C CD1 . ILE E 1 67  ? 44.350  -28.300 50.621  1.00 39.12  ? 67  ILE E CD1 1 
ATOM   13140 N N   . ASP E 1 68  ? 41.438  -30.481 47.588  1.00 43.80  ? 68  ASP E N   1 
ATOM   13141 C CA  . ASP E 1 68  ? 41.992  -31.403 46.608  1.00 47.15  ? 68  ASP E CA  1 
ATOM   13142 C C   . ASP E 1 68  ? 43.489  -31.543 46.808  1.00 46.67  ? 68  ASP E C   1 
ATOM   13143 O O   . ASP E 1 68  ? 44.266  -30.807 46.192  1.00 50.11  ? 68  ASP E O   1 
ATOM   13144 C CB  . ASP E 1 68  ? 41.696  -30.912 45.185  1.00 47.80  ? 68  ASP E CB  1 
ATOM   13145 C CG  . ASP E 1 68  ? 42.359  -31.772 44.100  1.00 51.12  ? 68  ASP E CG  1 
ATOM   13146 O OD1 . ASP E 1 68  ? 42.826  -32.900 44.392  1.00 47.45  ? 68  ASP E OD1 1 
ATOM   13147 O OD2 . ASP E 1 68  ? 42.435  -31.287 42.946  1.00 54.64  ? 68  ASP E OD2 1 
ATOM   13148 N N   . GLY E 1 69  ? 43.901  -32.484 47.651  1.00 45.99  ? 69  GLY E N   1 
ATOM   13149 C CA  . GLY E 1 69  ? 45.320  -32.663 47.898  1.00 43.45  ? 69  GLY E CA  1 
ATOM   13150 C C   . GLY E 1 69  ? 46.121  -32.770 46.620  1.00 47.69  ? 69  GLY E C   1 
ATOM   13151 O O   . GLY E 1 69  ? 47.176  -32.148 46.488  1.00 42.01  ? 69  GLY E O   1 
ATOM   13152 N N   . THR E 1 70  ? 45.598  -33.514 45.638  1.00 49.73  ? 70  THR E N   1 
ATOM   13153 C CA  . THR E 1 70  ? 46.306  -33.735 44.379  1.00 49.28  ? 70  THR E CA  1 
ATOM   13154 C C   . THR E 1 70  ? 46.575  -32.453 43.609  1.00 45.15  ? 70  THR E C   1 
ATOM   13155 O O   . THR E 1 70  ? 47.365  -32.480 42.657  1.00 47.95  ? 70  THR E O   1 
ATOM   13156 C CB  . THR E 1 70  ? 45.526  -34.694 43.476  1.00 48.91  ? 70  THR E CB  1 
ATOM   13157 O OG1 . THR E 1 70  ? 44.273  -34.097 43.107  1.00 49.91  ? 70  THR E OG1 1 
ATOM   13158 C CG2 . THR E 1 70  ? 45.289  -36.023 44.186  1.00 47.25  ? 70  THR E CG2 1 
ATOM   13159 N N   . SER E 1 71  ? 45.933  -31.348 43.971  1.00 50.24  ? 71  SER E N   1 
ATOM   13160 C CA  . SER E 1 71  ? 46.246  -30.051 43.387  1.00 47.72  ? 71  SER E CA  1 
ATOM   13161 C C   . SER E 1 71  ? 47.348  -29.331 44.143  1.00 43.99  ? 71  SER E C   1 
ATOM   13162 O O   . SER E 1 71  ? 47.663  -28.190 43.801  1.00 42.55  ? 71  SER E O   1 
ATOM   13163 C CB  . SER E 1 71  ? 45.003  -29.163 43.355  1.00 42.18  ? 71  SER E CB  1 
ATOM   13164 O OG  . SER E 1 71  ? 44.782  -28.626 44.635  1.00 39.80  ? 71  SER E OG  1 
ATOM   13165 N N   . VAL E 1 72  ? 47.911  -29.962 45.173  1.00 43.96  ? 72  VAL E N   1 
ATOM   13166 C CA  . VAL E 1 72  ? 48.982  -29.406 45.990  1.00 38.60  ? 72  VAL E CA  1 
ATOM   13167 C C   . VAL E 1 72  ? 50.271  -30.106 45.607  1.00 38.18  ? 72  VAL E C   1 
ATOM   13168 O O   . VAL E 1 72  ? 50.307  -31.337 45.517  1.00 36.56  ? 72  VAL E O   1 
ATOM   13169 C CB  . VAL E 1 72  ? 48.707  -29.587 47.492  1.00 37.33  ? 72  VAL E CB  1 
ATOM   13170 C CG1 . VAL E 1 72  ? 49.766  -28.879 48.320  1.00 35.71  ? 72  VAL E CG1 1 
ATOM   13171 C CG2 . VAL E 1 72  ? 47.323  -29.074 47.849  1.00 46.22  ? 72  VAL E CG2 1 
ATOM   13172 N N   . HIS E 1 73  ? 51.327  -29.330 45.401  1.00 38.49  ? 73  HIS E N   1 
ATOM   13173 C CA  . HIS E 1 73  ? 52.635  -29.865 45.058  1.00 43.26  ? 73  HIS E CA  1 
ATOM   13174 C C   . HIS E 1 73  ? 53.651  -29.505 46.140  1.00 43.28  ? 73  HIS E C   1 
ATOM   13175 O O   . HIS E 1 73  ? 53.612  -28.408 46.715  1.00 38.95  ? 73  HIS E O   1 
ATOM   13176 C CB  . HIS E 1 73  ? 53.093  -29.331 43.694  1.00 42.22  ? 73  HIS E CB  1 
ATOM   13177 C CG  . HIS E 1 73  ? 51.970  -29.083 42.734  1.00 44.08  ? 73  HIS E CG  1 
ATOM   13178 N ND1 . HIS E 1 73  ? 51.600  -29.995 41.766  1.00 44.97  ? 73  HIS E ND1 1 
ATOM   13179 C CD2 . HIS E 1 73  ? 51.130  -28.027 42.599  1.00 42.99  ? 73  HIS E CD2 1 
ATOM   13180 C CE1 . HIS E 1 73  ? 50.585  -29.508 41.073  1.00 49.27  ? 73  HIS E CE1 1 
ATOM   13181 N NE2 . HIS E 1 73  ? 50.281  -28.315 41.557  1.00 47.95  ? 73  HIS E NE2 1 
ATOM   13182 N N   . VAL E 1 74  ? 54.554  -30.437 46.426  1.00 39.43  ? 74  VAL E N   1 
ATOM   13183 C CA  . VAL E 1 74  ? 55.651  -30.218 47.358  1.00 40.28  ? 74  VAL E CA  1 
ATOM   13184 C C   . VAL E 1 74  ? 56.947  -30.259 46.564  1.00 43.76  ? 74  VAL E C   1 
ATOM   13185 O O   . VAL E 1 74  ? 57.167  -31.192 45.782  1.00 43.07  ? 74  VAL E O   1 
ATOM   13186 C CB  . VAL E 1 74  ? 55.652  -31.262 48.487  1.00 39.21  ? 74  VAL E CB  1 
ATOM   13187 C CG1 . VAL E 1 74  ? 56.940  -31.194 49.283  1.00 40.12  ? 74  VAL E CG1 1 
ATOM   13188 C CG2 . VAL E 1 74  ? 54.457  -31.041 49.396  1.00 41.36  ? 74  VAL E CG2 1 
ATOM   13189 N N   . GLU E 1 75  ? 57.799  -29.249 46.759  1.00 42.51  ? 75  GLU E N   1 
ATOM   13190 C CA  . GLU E 1 75  ? 59.044  -29.079 46.004  1.00 44.27  ? 75  GLU E CA  1 
ATOM   13191 C C   . GLU E 1 75  ? 60.199  -29.154 46.997  1.00 43.60  ? 75  GLU E C   1 
ATOM   13192 O O   . GLU E 1 75  ? 60.368  -28.253 47.826  1.00 49.28  ? 75  GLU E O   1 
ATOM   13193 C CB  . GLU E 1 75  ? 59.047  -27.742 45.262  1.00 43.71  ? 75  GLU E CB  1 
ATOM   13194 C CG  . GLU E 1 75  ? 58.252  -27.670 43.949  1.00 48.45  ? 75  GLU E CG  1 
ATOM   13195 C CD  . GLU E 1 75  ? 58.678  -28.660 42.870  1.00 46.11  ? 75  GLU E CD  1 
ATOM   13196 O OE1 . GLU E 1 75  ? 59.759  -29.287 42.986  1.00 46.09  ? 75  GLU E OE1 1 
ATOM   13197 O OE2 . GLU E 1 75  ? 57.902  -28.812 41.899  1.00 46.39  ? 75  GLU E OE2 1 
ATOM   13198 N N   . ARG E 1 76  ? 61.004  -30.206 46.911  1.00 46.39  ? 76  ARG E N   1 
ATOM   13199 C CA  . ARG E 1 76  ? 62.053  -30.429 47.896  1.00 47.62  ? 76  ARG E CA  1 
ATOM   13200 C C   . ARG E 1 76  ? 63.316  -29.642 47.553  1.00 49.93  ? 76  ARG E C   1 
ATOM   13201 O O   . ARG E 1 76  ? 63.545  -29.243 46.411  1.00 51.23  ? 76  ARG E O   1 
ATOM   13202 C CB  . ARG E 1 76  ? 62.399  -31.917 48.003  1.00 55.48  ? 76  ARG E CB  1 
ATOM   13203 C CG  . ARG E 1 76  ? 61.474  -32.719 48.910  1.00 58.96  ? 76  ARG E CG  1 
ATOM   13204 C CD  . ARG E 1 76  ? 61.438  -34.204 48.533  1.00 62.21  ? 76  ARG E CD  1 
ATOM   13205 N NE  . ARG E 1 76  ? 60.074  -34.718 48.513  1.00 64.49  ? 76  ARG E NE  1 
ATOM   13206 C CZ  . ARG E 1 76  ? 59.338  -34.934 49.595  1.00 56.45  ? 76  ARG E CZ  1 
ATOM   13207 N NH1 . ARG E 1 76  ? 59.817  -34.724 50.810  1.00 58.18  ? 76  ARG E NH1 1 
ATOM   13208 N NH2 . ARG E 1 76  ? 58.087  -35.360 49.456  1.00 50.42  ? 76  ARG E NH2 1 
ATOM   13209 N N   . THR E 1 77  ? 64.137  -29.411 48.574  1.00 47.36  ? 77  THR E N   1 
ATOM   13210 C CA  . THR E 1 77  ? 65.490  -28.909 48.395  1.00 49.17  ? 77  THR E CA  1 
ATOM   13211 C C   . THR E 1 77  ? 66.384  -29.633 49.382  1.00 46.40  ? 77  THR E C   1 
ATOM   13212 O O   . THR E 1 77  ? 65.922  -30.102 50.425  1.00 50.71  ? 77  THR E O   1 
ATOM   13213 C CB  . THR E 1 77  ? 65.616  -27.401 48.634  1.00 46.37  ? 77  THR E CB  1 
ATOM   13214 O OG1 . THR E 1 77  ? 65.169  -27.103 49.959  1.00 40.86  ? 77  THR E OG1 1 
ATOM   13215 C CG2 . THR E 1 77  ? 64.829  -26.580 47.591  1.00 40.99  ? 77  THR E CG2 1 
ATOM   13216 N N   . GLN E 1 78  ? 67.665  -29.713 49.052  1.00 51.32  ? 78  GLN E N   1 
ATOM   13217 C CA  . GLN E 1 78  ? 68.622  -30.417 49.897  1.00 56.73  ? 78  GLN E CA  1 
ATOM   13218 C C   . GLN E 1 78  ? 69.258  -29.521 50.958  1.00 55.10  ? 78  GLN E C   1 
ATOM   13219 O O   . GLN E 1 78  ? 70.105  -30.000 51.719  1.00 59.50  ? 78  GLN E O   1 
ATOM   13220 C CB  . GLN E 1 78  ? 69.721  -31.068 49.033  1.00 56.67  ? 78  GLN E CB  1 
ATOM   13221 C CG  . GLN E 1 78  ? 69.340  -32.424 48.397  1.00 59.19  ? 78  GLN E CG  1 
ATOM   13222 C CD  . GLN E 1 78  ? 70.434  -32.996 47.479  1.00 62.76  ? 78  GLN E CD  1 
ATOM   13223 O OE1 . GLN E 1 78  ? 70.145  -33.664 46.484  1.00 61.03  ? 78  GLN E OE1 1 
ATOM   13224 N NE2 . GLN E 1 78  ? 71.691  -32.727 47.814  1.00 63.94  ? 78  GLN E NE2 1 
ATOM   13225 N N   . THR E 1 79  ? 68.871  -28.252 51.045  1.00 53.82  ? 79  THR E N   1 
ATOM   13226 C CA  . THR E 1 79  ? 69.509  -27.317 51.960  1.00 51.88  ? 79  THR E CA  1 
ATOM   13227 C C   . THR E 1 79  ? 68.495  -26.282 52.393  1.00 46.90  ? 79  THR E C   1 
ATOM   13228 O O   . THR E 1 79  ? 67.502  -26.043 51.689  1.00 44.90  ? 79  THR E O   1 
ATOM   13229 C CB  . THR E 1 79  ? 70.708  -26.612 51.310  1.00 47.86  ? 79  THR E CB  1 
ATOM   13230 O OG1 . THR E 1 79  ? 70.420  -26.376 49.929  1.00 56.68  ? 79  THR E OG1 1 
ATOM   13231 C CG2 . THR E 1 79  ? 71.976  -27.453 51.451  1.00 57.55  ? 79  THR E CG2 1 
ATOM   13232 N N   . PRO E 1 80  ? 68.721  -25.621 53.528  1.00 44.82  ? 80  PRO E N   1 
ATOM   13233 C CA  . PRO E 1 80  ? 67.840  -24.532 53.947  1.00 39.02  ? 80  PRO E CA  1 
ATOM   13234 C C   . PRO E 1 80  ? 67.652  -23.502 52.843  1.00 43.19  ? 80  PRO E C   1 
ATOM   13235 O O   . PRO E 1 80  ? 68.501  -23.330 51.963  1.00 44.08  ? 80  PRO E O   1 
ATOM   13236 C CB  . PRO E 1 80  ? 68.568  -23.931 55.152  1.00 43.16  ? 80  PRO E CB  1 
ATOM   13237 C CG  . PRO E 1 80  ? 69.368  -25.071 55.708  1.00 45.54  ? 80  PRO E CG  1 
ATOM   13238 C CD  . PRO E 1 80  ? 69.778  -25.898 54.525  1.00 47.23  ? 80  PRO E CD  1 
ATOM   13239 N N   . LEU E 1 81  ? 66.519  -22.809 52.904  1.00 37.83  ? 81  LEU E N   1 
ATOM   13240 C CA  . LEU E 1 81  ? 66.150  -21.846 51.870  1.00 39.93  ? 81  LEU E CA  1 
ATOM   13241 C C   . LEU E 1 81  ? 66.865  -20.527 52.148  1.00 42.00  ? 81  LEU E C   1 
ATOM   13242 O O   . LEU E 1 81  ? 66.289  -19.534 52.599  1.00 37.62  ? 81  LEU E O   1 
ATOM   13243 C CB  . LEU E 1 81  ? 64.639  -21.687 51.804  1.00 33.75  ? 81  LEU E CB  1 
ATOM   13244 C CG  . LEU E 1 81  ? 64.026  -23.024 51.372  1.00 41.54  ? 81  LEU E CG  1 
ATOM   13245 C CD1 . LEU E 1 81  ? 62.504  -22.974 51.393  1.00 37.96  ? 81  LEU E CD1 1 
ATOM   13246 C CD2 . LEU E 1 81  ? 64.566  -23.469 50.002  1.00 38.48  ? 81  LEU E CD2 1 
ATOM   13247 N N   . SER E 1 82  ? 68.162  -20.548 51.864  1.00 42.87  ? 82  SER E N   1 
ATOM   13248 C CA  . SER E 1 82  ? 69.012  -19.389 52.012  1.00 37.02  ? 82  SER E CA  1 
ATOM   13249 C C   . SER E 1 82  ? 68.722  -18.374 50.909  1.00 40.05  ? 82  SER E C   1 
ATOM   13250 O O   . SER E 1 82  ? 68.056  -18.667 49.911  1.00 34.43  ? 82  SER E O   1 
ATOM   13251 C CB  . SER E 1 82  ? 70.471  -19.815 51.955  1.00 36.76  ? 82  SER E CB  1 
ATOM   13252 O OG  . SER E 1 82  ? 70.767  -20.251 50.645  1.00 37.63  ? 82  SER E OG  1 
ATOM   13253 N N   . GLU E 1 83  ? 69.233  -17.154 51.103  1.00 36.15  ? 83  GLU E N   1 
ATOM   13254 C CA  . GLU E 1 83  ? 69.291  -16.205 49.996  1.00 37.73  ? 83  GLU E CA  1 
ATOM   13255 C C   . GLU E 1 83  ? 69.862  -16.861 48.737  1.00 33.39  ? 83  GLU E C   1 
ATOM   13256 O O   . GLU E 1 83  ? 69.298  -16.726 47.648  1.00 32.23  ? 83  GLU E O   1 
ATOM   13257 C CB  . GLU E 1 83  ? 70.128  -14.979 50.380  1.00 42.23  ? 83  GLU E CB  1 
ATOM   13258 C CG  . GLU E 1 83  ? 69.436  -13.982 51.308  1.00 37.39  ? 83  GLU E CG  1 
ATOM   13259 C CD  . GLU E 1 83  ? 68.836  -12.800 50.556  1.00 43.62  ? 83  GLU E CD  1 
ATOM   13260 O OE1 . GLU E 1 83  ? 69.576  -11.978 49.916  1.00 45.26  ? 83  GLU E OE1 1 
ATOM   13261 O OE2 . GLU E 1 83  ? 67.597  -12.701 50.621  1.00 34.67  ? 83  GLU E OE2 1 
ATOM   13262 N N   . ALA E 1 84  ? 70.969  -17.600 48.870  1.00 32.13  ? 84  ALA E N   1 
ATOM   13263 C CA  . ALA E 1 84  ? 71.654  -18.087 47.670  1.00 35.43  ? 84  ALA E CA  1 
ATOM   13264 C C   . ALA E 1 84  ? 70.784  -19.075 46.908  1.00 37.69  ? 84  ALA E C   1 
ATOM   13265 O O   . ALA E 1 84  ? 70.760  -19.067 45.670  1.00 39.75  ? 84  ALA E O   1 
ATOM   13266 C CB  . ALA E 1 84  ? 73.006  -18.710 48.028  1.00 30.46  ? 84  ALA E CB  1 
ATOM   13267 N N   . VAL E 1 85  ? 70.020  -19.899 47.628  1.00 35.04  ? 85  VAL E N   1 
ATOM   13268 C CA  . VAL E 1 85  ? 69.132  -20.854 46.971  1.00 32.64  ? 85  VAL E CA  1 
ATOM   13269 C C   . VAL E 1 85  ? 67.985  -20.135 46.267  1.00 34.18  ? 85  VAL E C   1 
ATOM   13270 O O   . VAL E 1 85  ? 67.625  -20.476 45.135  1.00 32.19  ? 85  VAL E O   1 
ATOM   13271 C CB  . VAL E 1 85  ? 68.627  -21.881 48.000  1.00 35.47  ? 85  VAL E CB  1 
ATOM   13272 C CG1 . VAL E 1 85  ? 67.585  -22.780 47.394  1.00 31.98  ? 85  VAL E CG1 1 
ATOM   13273 C CG2 . VAL E 1 85  ? 69.798  -22.703 48.534  1.00 33.09  ? 85  VAL E CG2 1 
ATOM   13274 N N   . LEU E 1 86  ? 67.385  -19.133 46.921  1.00 31.42  ? 86  LEU E N   1 
ATOM   13275 C CA  . LEU E 1 86  ? 66.324  -18.362 46.283  1.00 33.38  ? 86  LEU E CA  1 
ATOM   13276 C C   . LEU E 1 86  ? 66.827  -17.626 45.050  1.00 32.95  ? 86  LEU E C   1 
ATOM   13277 O O   . LEU E 1 86  ? 66.019  -17.212 44.214  1.00 27.74  ? 86  LEU E O   1 
ATOM   13278 C CB  . LEU E 1 86  ? 65.710  -17.356 47.269  1.00 30.65  ? 86  LEU E CB  1 
ATOM   13279 C CG  . LEU E 1 86  ? 65.234  -17.837 48.655  1.00 33.39  ? 86  LEU E CG  1 
ATOM   13280 C CD1 . LEU E 1 86  ? 64.754  -16.657 49.499  1.00 28.31  ? 86  LEU E CD1 1 
ATOM   13281 C CD2 . LEU E 1 86  ? 64.137  -18.866 48.548  1.00 30.16  ? 86  LEU E CD2 1 
ATOM   13282 N N   . GLN E 1 87  ? 68.141  -17.444 44.926  1.00 37.40  ? 87  GLN E N   1 
ATOM   13283 C CA  . GLN E 1 87  ? 68.732  -16.868 43.728  1.00 39.31  ? 87  GLN E CA  1 
ATOM   13284 C C   . GLN E 1 87  ? 69.146  -17.920 42.709  1.00 42.69  ? 87  GLN E C   1 
ATOM   13285 O O   . GLN E 1 87  ? 69.418  -17.561 41.558  1.00 35.57  ? 87  GLN E O   1 
ATOM   13286 C CB  . GLN E 1 87  ? 69.943  -15.993 44.099  1.00 34.51  ? 87  GLN E CB  1 
ATOM   13287 C CG  . GLN E 1 87  ? 69.599  -14.973 45.178  1.00 42.98  ? 87  GLN E CG  1 
ATOM   13288 C CD  . GLN E 1 87  ? 70.477  -13.757 45.163  1.00 44.77  ? 87  GLN E CD  1 
ATOM   13289 O OE1 . GLN E 1 87  ? 71.364  -13.604 46.008  1.00 44.33  ? 87  GLN E OE1 1 
ATOM   13290 N NE2 . GLN E 1 87  ? 70.232  -12.867 44.203  1.00 45.43  ? 87  GLN E NE2 1 
ATOM   13291 N N   . ASP E 1 88  ? 69.166  -19.202 43.090  1.00 38.97  ? 88  ASP E N   1 
ATOM   13292 C CA  . ASP E 1 88  ? 69.719  -20.248 42.222  1.00 39.85  ? 88  ASP E CA  1 
ATOM   13293 C C   . ASP E 1 88  ? 68.834  -20.480 41.003  1.00 42.33  ? 88  ASP E C   1 
ATOM   13294 O O   . ASP E 1 88  ? 67.657  -20.840 41.156  1.00 42.94  ? 88  ASP E O   1 
ATOM   13295 C CB  . ASP E 1 88  ? 69.889  -21.549 42.996  1.00 44.24  ? 88  ASP E CB  1 
ATOM   13296 C CG  . ASP E 1 88  ? 70.721  -22.572 42.239  1.00 49.52  ? 88  ASP E CG  1 
ATOM   13297 O OD1 . ASP E 1 88  ? 70.393  -22.852 41.066  1.00 49.83  ? 88  ASP E OD1 1 
ATOM   13298 O OD2 . ASP E 1 88  ? 71.696  -23.106 42.819  1.00 56.49  ? 88  ASP E OD2 1 
ATOM   13299 N N   . PRO E 1 89  ? 69.358  -20.327 39.786  1.00 47.18  ? 89  PRO E N   1 
ATOM   13300 C CA  . PRO E 1 89  ? 68.488  -20.406 38.597  1.00 42.23  ? 89  PRO E CA  1 
ATOM   13301 C C   . PRO E 1 89  ? 67.875  -21.780 38.386  1.00 42.22  ? 89  PRO E C   1 
ATOM   13302 O O   . PRO E 1 89  ? 66.828  -21.890 37.729  1.00 38.17  ? 89  PRO E O   1 
ATOM   13303 C CB  . PRO E 1 89  ? 69.434  -20.020 37.448  1.00 44.99  ? 89  PRO E CB  1 
ATOM   13304 C CG  . PRO E 1 89  ? 70.593  -19.297 38.122  1.00 48.41  ? 89  PRO E CG  1 
ATOM   13305 C CD  . PRO E 1 89  ? 70.752  -19.995 39.442  1.00 39.64  ? 89  PRO E CD  1 
ATOM   13306 N N   . GLU E 1 90  ? 68.501  -22.833 38.914  1.00 43.32  ? 90  GLU E N   1 
ATOM   13307 C CA  . GLU E 1 90  ? 67.868  -24.150 38.945  1.00 45.06  ? 90  GLU E CA  1 
ATOM   13308 C C   . GLU E 1 90  ? 66.600  -24.113 39.798  1.00 44.84  ? 90  GLU E C   1 
ATOM   13309 O O   . GLU E 1 90  ? 65.495  -24.402 39.317  1.00 40.75  ? 90  GLU E O   1 
ATOM   13310 C CB  . GLU E 1 90  ? 68.869  -25.188 39.479  1.00 47.98  ? 90  GLU E CB  1 
ATOM   13311 C CG  . GLU E 1 90  ? 68.576  -26.642 39.110  1.00 54.02  ? 90  GLU E CG  1 
ATOM   13312 C CD  . GLU E 1 90  ? 67.936  -27.434 40.252  1.00 66.37  ? 90  GLU E CD  1 
ATOM   13313 O OE1 . GLU E 1 90  ? 67.775  -26.863 41.358  1.00 67.28  ? 90  GLU E OE1 1 
ATOM   13314 O OE2 . GLU E 1 90  ? 67.591  -28.625 40.042  1.00 64.55  ? 90  GLU E OE2 1 
ATOM   13315 N N   . PHE E 1 91  ? 66.754  -23.744 41.077  1.00 46.12  ? 91  PHE E N   1 
ATOM   13316 C CA  . PHE E 1 91  ? 65.621  -23.564 41.985  1.00 36.78  ? 91  PHE E CA  1 
ATOM   13317 C C   . PHE E 1 91  ? 64.541  -22.690 41.370  1.00 39.24  ? 91  PHE E C   1 
ATOM   13318 O O   . PHE E 1 91  ? 63.342  -22.949 41.547  1.00 35.33  ? 91  PHE E O   1 
ATOM   13319 C CB  . PHE E 1 91  ? 66.122  -22.950 43.285  1.00 37.22  ? 91  PHE E CB  1 
ATOM   13320 C CG  . PHE E 1 91  ? 65.050  -22.717 44.312  1.00 39.54  ? 91  PHE E CG  1 
ATOM   13321 C CD1 . PHE E 1 91  ? 64.693  -23.726 45.194  1.00 38.16  ? 91  PHE E CD1 1 
ATOM   13322 C CD2 . PHE E 1 91  ? 64.436  -21.476 44.432  1.00 35.77  ? 91  PHE E CD2 1 
ATOM   13323 C CE1 . PHE E 1 91  ? 63.710  -23.516 46.168  1.00 46.11  ? 91  PHE E CE1 1 
ATOM   13324 C CE2 . PHE E 1 91  ? 63.455  -21.258 45.396  1.00 37.47  ? 91  PHE E CE2 1 
ATOM   13325 C CZ  . PHE E 1 91  ? 63.092  -22.280 46.267  1.00 42.88  ? 91  PHE E CZ  1 
ATOM   13326 N N   . ILE E 1 92  ? 64.947  -21.650 40.637  1.00 38.63  ? 92  ILE E N   1 
ATOM   13327 C CA  . ILE E 1 92  ? 63.970  -20.782 39.996  1.00 36.15  ? 92  ILE E CA  1 
ATOM   13328 C C   . ILE E 1 92  ? 63.263  -21.515 38.860  1.00 41.34  ? 92  ILE E C   1 
ATOM   13329 O O   . ILE E 1 92  ? 62.082  -21.257 38.579  1.00 43.74  ? 92  ILE E O   1 
ATOM   13330 C CB  . ILE E 1 92  ? 64.647  -19.483 39.522  1.00 38.98  ? 92  ILE E CB  1 
ATOM   13331 C CG1 . ILE E 1 92  ? 65.124  -18.675 40.734  1.00 44.83  ? 92  ILE E CG1 1 
ATOM   13332 C CG2 . ILE E 1 92  ? 63.687  -18.614 38.696  1.00 36.66  ? 92  ILE E CG2 1 
ATOM   13333 C CD1 . ILE E 1 92  ? 65.411  -17.225 40.426  1.00 43.64  ? 92  ILE E CD1 1 
ATOM   13334 N N   . ASP E 1 93  ? 63.937  -22.462 38.212  1.00 39.80  ? 93  ASP E N   1 
ATOM   13335 C CA  . ASP E 1 93  ? 63.254  -23.194 37.152  1.00 40.17  ? 93  ASP E CA  1 
ATOM   13336 C C   . ASP E 1 93  ? 62.272  -24.218 37.703  1.00 38.19  ? 93  ASP E C   1 
ATOM   13337 O O   . ASP E 1 93  ? 61.213  -24.440 37.111  1.00 37.55  ? 93  ASP E O   1 
ATOM   13338 C CB  . ASP E 1 93  ? 64.275  -23.854 36.234  1.00 42.35  ? 93  ASP E CB  1 
ATOM   13339 C CG  . ASP E 1 93  ? 64.600  -22.987 35.055  1.00 45.63  ? 93  ASP E CG  1 
ATOM   13340 O OD1 . ASP E 1 93  ? 63.713  -22.857 34.181  1.00 46.52  ? 93  ASP E OD1 1 
ATOM   13341 O OD2 . ASP E 1 93  ? 65.717  -22.424 35.012  1.00 44.13  ? 93  ASP E OD2 1 
ATOM   13342 N N   . ARG E 1 94  ? 62.596  -24.854 38.827  1.00 38.76  ? 94  ARG E N   1 
ATOM   13343 C CA  . ARG E 1 94  ? 61.637  -25.765 39.441  1.00 36.74  ? 94  ARG E CA  1 
ATOM   13344 C C   . ARG E 1 94  ? 60.356  -25.035 39.838  1.00 40.93  ? 94  ARG E C   1 
ATOM   13345 O O   . ARG E 1 94  ? 59.254  -25.583 39.704  1.00 39.01  ? 94  ARG E O   1 
ATOM   13346 C CB  . ARG E 1 94  ? 62.276  -26.441 40.643  1.00 39.69  ? 94  ARG E CB  1 
ATOM   13347 C CG  . ARG E 1 94  ? 63.613  -27.070 40.321  1.00 44.03  ? 94  ARG E CG  1 
ATOM   13348 C CD  . ARG E 1 94  ? 64.223  -27.633 41.564  1.00 45.50  ? 94  ARG E CD  1 
ATOM   13349 N NE  . ARG E 1 94  ? 63.221  -28.321 42.367  1.00 49.63  ? 94  ARG E NE  1 
ATOM   13350 C CZ  . ARG E 1 94  ? 63.455  -28.836 43.565  1.00 48.53  ? 94  ARG E CZ  1 
ATOM   13351 N NH1 . ARG E 1 94  ? 64.653  -28.760 44.126  1.00 43.04  ? 94  ARG E NH1 1 
ATOM   13352 N NH2 . ARG E 1 94  ? 62.466  -29.447 44.213  1.00 50.24  ? 94  ARG E NH2 1 
ATOM   13353 N N   . LEU E 1 95  ? 60.479  -23.788 40.310  1.00 36.60  ? 95  LEU E N   1 
ATOM   13354 C CA  . LEU E 1 95  ? 59.292  -23.005 40.650  1.00 38.08  ? 95  LEU E CA  1 
ATOM   13355 C C   . LEU E 1 95  ? 58.537  -22.554 39.397  1.00 40.19  ? 95  LEU E C   1 
ATOM   13356 O O   . LEU E 1 95  ? 57.303  -22.624 39.351  1.00 41.50  ? 95  LEU E O   1 
ATOM   13357 C CB  . LEU E 1 95  ? 59.685  -21.799 41.511  1.00 33.56  ? 95  LEU E CB  1 
ATOM   13358 C CG  . LEU E 1 95  ? 60.165  -22.105 42.946  1.00 35.58  ? 95  LEU E CG  1 
ATOM   13359 C CD1 . LEU E 1 95  ? 60.165  -20.853 43.821  1.00 31.53  ? 95  LEU E CD1 1 
ATOM   13360 C CD2 . LEU E 1 95  ? 59.343  -23.219 43.611  1.00 29.57  ? 95  LEU E CD2 1 
ATOM   13361 N N   . ALA E 1 96  ? 59.252  -22.096 38.366  1.00 35.70  ? 96  ALA E N   1 
ATOM   13362 C CA  . ALA E 1 96  ? 58.564  -21.557 37.194  1.00 41.87  ? 96  ALA E CA  1 
ATOM   13363 C C   . ALA E 1 96  ? 57.750  -22.625 36.477  1.00 45.69  ? 96  ALA E C   1 
ATOM   13364 O O   . ALA E 1 96  ? 56.740  -22.307 35.834  1.00 42.92  ? 96  ALA E O   1 
ATOM   13365 C CB  . ALA E 1 96  ? 59.561  -20.927 36.223  1.00 42.05  ? 96  ALA E CB  1 
ATOM   13366 N N   . ALA E 1 97  ? 58.168  -23.893 36.577  1.00 42.26  ? 97  ALA E N   1 
ATOM   13367 C CA  . ALA E 1 97  ? 57.374  -24.973 36.009  1.00 46.85  ? 97  ALA E CA  1 
ATOM   13368 C C   . ALA E 1 97  ? 55.956  -24.983 36.573  1.00 47.95  ? 97  ALA E C   1 
ATOM   13369 O O   . ALA E 1 97  ? 55.039  -25.474 35.907  1.00 44.96  ? 97  ALA E O   1 
ATOM   13370 C CB  . ALA E 1 97  ? 58.069  -26.316 36.250  1.00 37.98  ? 97  ALA E CB  1 
ATOM   13371 N N   . HIS E 1 98  ? 55.750  -24.429 37.772  1.00 44.45  ? 98  HIS E N   1 
ATOM   13372 C CA  . HIS E 1 98  ? 54.404  -24.309 38.323  1.00 44.06  ? 98  HIS E CA  1 
ATOM   13373 C C   . HIS E 1 98  ? 53.746  -22.983 37.968  1.00 48.60  ? 98  HIS E C   1 
ATOM   13374 O O   . HIS E 1 98  ? 52.538  -22.952 37.715  1.00 48.62  ? 98  HIS E O   1 
ATOM   13375 C CB  . HIS E 1 98  ? 54.425  -24.461 39.845  1.00 42.82  ? 98  HIS E CB  1 
ATOM   13376 C CG  . HIS E 1 98  ? 54.813  -25.825 40.321  1.00 39.03  ? 98  HIS E CG  1 
ATOM   13377 N ND1 . HIS E 1 98  ? 53.895  -26.828 40.539  1.00 44.09  ? 98  HIS E ND1 1 
ATOM   13378 C CD2 . HIS E 1 98  ? 56.020  -26.342 40.650  1.00 42.69  ? 98  HIS E CD2 1 
ATOM   13379 C CE1 . HIS E 1 98  ? 54.520  -27.911 40.964  1.00 39.26  ? 98  HIS E CE1 1 
ATOM   13380 N NE2 . HIS E 1 98  ? 55.810  -27.641 41.045  1.00 45.96  ? 98  HIS E NE2 1 
ATOM   13381 N N   . THR E 1 99  ? 54.507  -21.879 37.951  1.00 46.06  ? 99  THR E N   1 
ATOM   13382 C CA  . THR E 1 99  ? 53.914  -20.557 37.790  1.00 38.20  ? 99  THR E CA  1 
ATOM   13383 C C   . THR E 1 99  ? 53.710  -20.161 36.335  1.00 47.44  ? 99  THR E C   1 
ATOM   13384 O O   . THR E 1 99  ? 52.880  -19.281 36.056  1.00 46.10  ? 99  THR E O   1 
ATOM   13385 C CB  . THR E 1 99  ? 54.778  -19.499 38.480  1.00 41.77  ? 99  THR E CB  1 
ATOM   13386 O OG1 . THR E 1 99  ? 56.057  -19.430 37.843  1.00 42.94  ? 99  THR E OG1 1 
ATOM   13387 C CG2 . THR E 1 99  ? 54.998  -19.876 39.925  1.00 41.85  ? 99  THR E CG2 1 
ATOM   13388 N N   . GLY E 1 100 ? 54.444  -20.775 35.411  1.00 45.90  ? 100 GLY E N   1 
ATOM   13389 C CA  . GLY E 1 100 ? 54.200  -20.535 33.997  1.00 41.84  ? 100 GLY E CA  1 
ATOM   13390 C C   . GLY E 1 100 ? 54.455  -19.086 33.636  1.00 42.38  ? 100 GLY E C   1 
ATOM   13391 O O   . GLY E 1 100 ? 55.575  -18.580 33.751  1.00 42.94  ? 100 GLY E O   1 
ATOM   13392 N N   . THR E 1 101 ? 53.415  -18.400 33.177  1.00 42.19  ? 101 THR E N   1 
ATOM   13393 C CA  . THR E 1 101 ? 53.502  -16.962 32.975  1.00 39.86  ? 101 THR E CA  1 
ATOM   13394 C C   . THR E 1 101 ? 53.395  -16.183 34.276  1.00 44.86  ? 101 THR E C   1 
ATOM   13395 O O   . THR E 1 101 ? 53.324  -14.949 34.228  1.00 41.05  ? 101 THR E O   1 
ATOM   13396 C CB  . THR E 1 101 ? 52.396  -16.477 32.033  1.00 41.43  ? 101 THR E CB  1 
ATOM   13397 O OG1 . THR E 1 101 ? 51.167  -16.409 32.761  1.00 37.82  ? 101 THR E OG1 1 
ATOM   13398 C CG2 . THR E 1 101 ? 52.229  -17.410 30.835  1.00 40.19  ? 101 THR E CG2 1 
ATOM   13399 N N   . GLY E 1 102 ? 53.336  -16.867 35.426  1.00 46.55  ? 102 GLY E N   1 
ATOM   13400 C CA  . GLY E 1 102 ? 53.155  -16.225 36.715  1.00 41.19  ? 102 GLY E CA  1 
ATOM   13401 C C   . GLY E 1 102 ? 51.782  -15.640 36.974  1.00 44.17  ? 102 GLY E C   1 
ATOM   13402 O O   . GLY E 1 102 ? 51.514  -15.219 38.107  1.00 37.92  ? 102 GLY E O   1 
ATOM   13403 N N   . ALA E 1 103 ? 50.894  -15.605 35.978  1.00 43.48  ? 103 ALA E N   1 
ATOM   13404 C CA  . ALA E 1 103 ? 49.571  -15.027 36.185  1.00 44.56  ? 103 ALA E CA  1 
ATOM   13405 C C   . ALA E 1 103 ? 48.781  -15.850 37.195  1.00 43.40  ? 103 ALA E C   1 
ATOM   13406 O O   . ALA E 1 103 ? 48.738  -17.083 37.122  1.00 43.73  ? 103 ALA E O   1 
ATOM   13407 C CB  . ALA E 1 103 ? 48.811  -14.940 34.860  1.00 43.90  ? 103 ALA E CB  1 
ATOM   13408 N N   . GLY E 1 104 ? 48.169  -15.160 38.151  1.00 38.77  ? 104 GLY E N   1 
ATOM   13409 C CA  . GLY E 1 104 ? 47.447  -15.804 39.221  1.00 40.26  ? 104 GLY E CA  1 
ATOM   13410 C C   . GLY E 1 104 ? 48.281  -16.281 40.397  1.00 37.94  ? 104 GLY E C   1 
ATOM   13411 O O   . GLY E 1 104 ? 47.711  -16.783 41.374  1.00 38.18  ? 104 GLY E O   1 
ATOM   13412 N N   . TRP E 1 105 ? 49.598  -16.168 40.349  1.00 33.86  ? 105 TRP E N   1 
ATOM   13413 C CA  . TRP E 1 105 ? 50.403  -16.686 41.446  1.00 36.97  ? 105 TRP E CA  1 
ATOM   13414 C C   . TRP E 1 105 ? 50.913  -15.557 42.331  1.00 38.54  ? 105 TRP E C   1 
ATOM   13415 O O   . TRP E 1 105 ? 50.940  -14.385 41.940  1.00 38.13  ? 105 TRP E O   1 
ATOM   13416 C CB  . TRP E 1 105 ? 51.583  -17.501 40.928  1.00 40.16  ? 105 TRP E CB  1 
ATOM   13417 C CG  . TRP E 1 105 ? 51.205  -18.831 40.386  1.00 42.57  ? 105 TRP E CG  1 
ATOM   13418 C CD1 . TRP E 1 105 ? 50.646  -19.089 39.165  1.00 39.72  ? 105 TRP E CD1 1 
ATOM   13419 C CD2 . TRP E 1 105 ? 51.388  -20.097 41.023  1.00 40.59  ? 105 TRP E CD2 1 
ATOM   13420 N NE1 . TRP E 1 105 ? 50.462  -20.434 39.013  1.00 40.98  ? 105 TRP E NE1 1 
ATOM   13421 C CE2 . TRP E 1 105 ? 50.910  -21.080 40.136  1.00 42.50  ? 105 TRP E CE2 1 
ATOM   13422 C CE3 . TRP E 1 105 ? 51.911  -20.498 42.258  1.00 41.44  ? 105 TRP E CE3 1 
ATOM   13423 C CZ2 . TRP E 1 105 ? 50.929  -22.440 40.444  1.00 39.28  ? 105 TRP E CZ2 1 
ATOM   13424 C CZ3 . TRP E 1 105 ? 51.927  -21.849 42.566  1.00 35.24  ? 105 TRP E CZ3 1 
ATOM   13425 C CH2 . TRP E 1 105 ? 51.439  -22.804 41.660  1.00 40.60  ? 105 TRP E CH2 1 
ATOM   13426 N N   . SER E 1 106 ? 51.306  -15.938 43.546  1.00 33.21  ? 106 SER E N   1 
ATOM   13427 C CA  . SER E 1 106 ? 51.924  -15.049 44.514  1.00 28.28  ? 106 SER E CA  1 
ATOM   13428 C C   . SER E 1 106 ? 52.973  -15.831 45.290  1.00 31.24  ? 106 SER E C   1 
ATOM   13429 O O   . SER E 1 106 ? 52.856  -17.051 45.469  1.00 30.92  ? 106 SER E O   1 
ATOM   13430 C CB  . SER E 1 106 ? 50.883  -14.460 45.482  1.00 30.84  ? 106 SER E CB  1 
ATOM   13431 O OG  . SER E 1 106 ? 50.290  -15.493 46.260  1.00 33.52  ? 106 SER E OG  1 
ATOM   13432 N N   . LEU E 1 107 ? 54.006  -15.129 45.744  1.00 28.09  ? 107 LEU E N   1 
ATOM   13433 C CA  . LEU E 1 107 ? 54.952  -15.706 46.694  1.00 31.51  ? 107 LEU E CA  1 
ATOM   13434 C C   . LEU E 1 107 ? 54.436  -15.451 48.101  1.00 26.02  ? 107 LEU E C   1 
ATOM   13435 O O   . LEU E 1 107 ? 53.982  -14.346 48.407  1.00 30.75  ? 107 LEU E O   1 
ATOM   13436 C CB  . LEU E 1 107 ? 56.353  -15.107 46.529  1.00 28.06  ? 107 LEU E CB  1 
ATOM   13437 C CG  . LEU E 1 107 ? 57.504  -15.652 47.386  1.00 28.34  ? 107 LEU E CG  1 
ATOM   13438 C CD1 . LEU E 1 107 ? 57.634  -17.163 47.310  1.00 30.92  ? 107 LEU E CD1 1 
ATOM   13439 C CD2 . LEU E 1 107 ? 58.828  -15.014 46.993  1.00 31.83  ? 107 LEU E CD2 1 
ATOM   13440 N N   . PHE E 1 108 ? 54.495  -16.482 48.947  1.00 24.48  ? 108 PHE E N   1 
ATOM   13441 C CA  . PHE E 1 108 ? 54.046  -16.421 50.338  1.00 26.71  ? 108 PHE E CA  1 
ATOM   13442 C C   . PHE E 1 108 ? 55.231  -16.769 51.230  1.00 26.57  ? 108 PHE E C   1 
ATOM   13443 O O   . PHE E 1 108 ? 55.342  -17.909 51.702  1.00 22.05  ? 108 PHE E O   1 
ATOM   13444 C CB  . PHE E 1 108 ? 52.888  -17.385 50.588  1.00 28.90  ? 108 PHE E CB  1 
ATOM   13445 C CG  . PHE E 1 108 ? 52.214  -17.205 51.918  1.00 26.21  ? 108 PHE E CG  1 
ATOM   13446 C CD1 . PHE E 1 108 ? 51.396  -16.112 52.151  1.00 23.62  ? 108 PHE E CD1 1 
ATOM   13447 C CD2 . PHE E 1 108 ? 52.373  -18.153 52.924  1.00 21.39  ? 108 PHE E CD2 1 
ATOM   13448 C CE1 . PHE E 1 108 ? 50.753  -15.954 53.374  1.00 25.17  ? 108 PHE E CE1 1 
ATOM   13449 C CE2 . PHE E 1 108 ? 51.728  -18.005 54.146  1.00 25.15  ? 108 PHE E CE2 1 
ATOM   13450 C CZ  . PHE E 1 108 ? 50.918  -16.895 54.367  1.00 22.11  ? 108 PHE E CZ  1 
ATOM   13451 N N   . PRO E 1 109 ? 56.135  -15.801 51.499  1.00 28.53  ? 109 PRO E N   1 
ATOM   13452 C CA  . PRO E 1 109 ? 57.400  -16.124 52.186  1.00 26.78  ? 109 PRO E CA  1 
ATOM   13453 C C   . PRO E 1 109 ? 57.391  -15.881 53.685  1.00 23.33  ? 109 PRO E C   1 
ATOM   13454 O O   . PRO E 1 109 ? 56.718  -14.974 54.164  1.00 20.89  ? 109 PRO E O   1 
ATOM   13455 C CB  . PRO E 1 109 ? 58.397  -15.187 51.501  1.00 23.90  ? 109 PRO E CB  1 
ATOM   13456 C CG  . PRO E 1 109 ? 57.545  -13.952 51.220  1.00 27.95  ? 109 PRO E CG  1 
ATOM   13457 C CD  . PRO E 1 109 ? 56.141  -14.438 50.936  1.00 22.04  ? 109 PRO E CD  1 
ATOM   13458 N N   . CYS E 1 110 ? 58.156  -16.675 54.435  1.00 24.70  ? 110 CYS E N   1 
ATOM   13459 C CA  . CYS E 1 110 ? 58.272  -16.440 55.864  1.00 25.51  ? 110 CYS E CA  1 
ATOM   13460 C C   . CYS E 1 110 ? 58.853  -15.068 56.140  1.00 26.56  ? 110 CYS E C   1 
ATOM   13461 O O   . CYS E 1 110 ? 58.414  -14.365 57.058  1.00 25.20  ? 110 CYS E O   1 
ATOM   13462 C CB  . CYS E 1 110 ? 59.152  -17.496 56.518  1.00 27.68  ? 110 CYS E CB  1 
ATOM   13463 S SG  . CYS E 1 110 ? 59.323  -17.262 58.297  1.00 49.89  ? 110 CYS E SG  1 
ATOM   13464 N N   . VAL E 1 111 ? 59.861  -14.693 55.374  1.00 22.66  ? 111 VAL E N   1 
ATOM   13465 C CA  . VAL E 1 111 ? 60.600  -13.464 55.563  1.00 25.56  ? 111 VAL E CA  1 
ATOM   13466 C C   . VAL E 1 111 ? 60.658  -12.785 54.207  1.00 27.61  ? 111 VAL E C   1 
ATOM   13467 O O   . VAL E 1 111 ? 61.010  -13.420 53.210  1.00 27.65  ? 111 VAL E O   1 
ATOM   13468 C CB  . VAL E 1 111 ? 62.018  -13.724 56.106  1.00 29.12  ? 111 VAL E CB  1 
ATOM   13469 C CG1 . VAL E 1 111 ? 62.690  -12.433 56.355  1.00 28.92  ? 111 VAL E CG1 1 
ATOM   13470 C CG2 . VAL E 1 111 ? 61.986  -14.564 57.392  1.00 23.98  ? 111 VAL E CG2 1 
ATOM   13471 N N   . SER E 1 112 ? 60.267  -11.515 54.155  1.00 24.80  ? 112 SER E N   1 
ATOM   13472 C CA  . SER E 1 112 ? 60.324  -10.774 52.909  1.00 23.43  ? 112 SER E CA  1 
ATOM   13473 C C   . SER E 1 112 ? 61.745  -10.234 52.724  1.00 23.49  ? 112 SER E C   1 
ATOM   13474 O O   . SER E 1 112 ? 62.030  -9.050  52.893  1.00 18.82  ? 112 SER E O   1 
ATOM   13475 C CB  . SER E 1 112 ? 59.276  -9.676  52.917  1.00 21.75  ? 112 SER E CB  1 
ATOM   13476 O OG  . SER E 1 112 ? 57.990  -10.242 52.744  1.00 24.20  ? 112 SER E OG  1 
ATOM   13477 N N   . THR E 1 113 ? 62.659  -11.142 52.386  1.00 23.74  ? 113 THR E N   1 
ATOM   13478 C CA  . THR E 1 113 ? 64.034  -10.727 52.137  1.00 19.16  ? 113 THR E CA  1 
ATOM   13479 C C   . THR E 1 113 ? 64.186  -10.143 50.736  1.00 22.68  ? 113 THR E C   1 
ATOM   13480 O O   . THR E 1 113 ? 63.300  -10.247 49.887  1.00 20.13  ? 113 THR E O   1 
ATOM   13481 C CB  . THR E 1 113 ? 64.998  -11.898 52.264  1.00 24.52  ? 113 THR E CB  1 
ATOM   13482 O OG1 . THR E 1 113 ? 64.661  -12.900 51.278  1.00 23.73  ? 113 THR E OG1 1 
ATOM   13483 C CG2 . THR E 1 113 ? 64.926  -12.490 53.654  1.00 25.77  ? 113 THR E CG2 1 
ATOM   13484 N N   . ARG E 1 114 ? 65.359  -9.543  50.501  1.00 24.89  ? 114 ARG E N   1 
ATOM   13485 C CA  . ARG E 1 114 ? 65.725  -9.081  49.171  1.00 22.49  ? 114 ARG E CA  1 
ATOM   13486 C C   . ARG E 1 114 ? 65.618  -10.196 48.135  1.00 26.16  ? 114 ARG E C   1 
ATOM   13487 O O   . ARG E 1 114 ? 65.065  -9.995  47.049  1.00 24.76  ? 114 ARG E O   1 
ATOM   13488 C CB  . ARG E 1 114 ? 67.147  -8.518  49.190  1.00 21.73  ? 114 ARG E CB  1 
ATOM   13489 C CG  . ARG E 1 114 ? 67.785  -8.379  47.811  1.00 27.13  ? 114 ARG E CG  1 
ATOM   13490 C CD  . ARG E 1 114 ? 69.016  -7.467  47.879  1.00 30.29  ? 114 ARG E CD  1 
ATOM   13491 N NE  . ARG E 1 114 ? 69.660  -7.245  46.590  1.00 28.41  ? 114 ARG E NE  1 
ATOM   13492 C CZ  . ARG E 1 114 ? 69.479  -6.173  45.826  1.00 29.08  ? 114 ARG E CZ  1 
ATOM   13493 N NH1 . ARG E 1 114 ? 68.611  -5.226  46.152  1.00 24.62  ? 114 ARG E NH1 1 
ATOM   13494 N NH2 . ARG E 1 114 ? 70.199  -6.041  44.715  1.00 23.87  ? 114 ARG E NH2 1 
ATOM   13495 N N   . ALA E 1 115 ? 66.172  -11.374 48.437  1.00 28.01  ? 115 ALA E N   1 
ATOM   13496 C CA  . ALA E 1 115 ? 66.124  -12.441 47.438  1.00 33.61  ? 115 ALA E CA  1 
ATOM   13497 C C   . ALA E 1 115 ? 64.700  -12.929 47.219  1.00 29.58  ? 115 ALA E C   1 
ATOM   13498 O O   . ALA E 1 115 ? 64.356  -13.332 46.101  1.00 32.34  ? 115 ALA E O   1 
ATOM   13499 C CB  . ALA E 1 115 ? 67.035  -13.605 47.822  1.00 29.20  ? 115 ALA E CB  1 
ATOM   13500 N N   . ALA E 1 116 ? 63.861  -12.877 48.259  1.00 23.30  ? 116 ALA E N   1 
ATOM   13501 C CA  . ALA E 1 116 ? 62.443  -13.181 48.092  1.00 25.98  ? 116 ALA E CA  1 
ATOM   13502 C C   . ALA E 1 116 ? 61.774  -12.195 47.152  1.00 30.04  ? 116 ALA E C   1 
ATOM   13503 O O   . ALA E 1 116 ? 60.947  -12.587 46.316  1.00 26.15  ? 116 ALA E O   1 
ATOM   13504 C CB  . ALA E 1 116 ? 61.728  -13.173 49.439  1.00 28.02  ? 116 ALA E CB  1 
ATOM   13505 N N   . ALA E 1 117 ? 62.114  -10.906 47.263  1.00 24.61  ? 117 ALA E N   1 
ATOM   13506 C CA  . ALA E 1 117 ? 61.472  -9.943  46.378  1.00 27.43  ? 117 ALA E CA  1 
ATOM   13507 C C   . ALA E 1 117 ? 61.949  -10.143 44.950  1.00 27.78  ? 117 ALA E C   1 
ATOM   13508 O O   . ALA E 1 117 ? 61.159  -10.055 44.002  1.00 22.59  ? 117 ALA E O   1 
ATOM   13509 C CB  . ALA E 1 117 ? 61.733  -8.510  46.855  1.00 27.19  ? 117 ALA E CB  1 
ATOM   13510 N N   . GLN E 1 118 ? 63.237  -10.440 44.783  1.00 24.92  ? 118 GLN E N   1 
ATOM   13511 C CA  . GLN E 1 118 ? 63.751  -10.709 43.451  1.00 31.20  ? 118 GLN E CA  1 
ATOM   13512 C C   . GLN E 1 118 ? 63.065  -11.927 42.836  1.00 34.61  ? 118 GLN E C   1 
ATOM   13513 O O   . GLN E 1 118 ? 62.776  -11.937 41.634  1.00 33.61  ? 118 GLN E O   1 
ATOM   13514 C CB  . GLN E 1 118 ? 65.272  -10.888 43.511  1.00 32.25  ? 118 GLN E CB  1 
ATOM   13515 C CG  . GLN E 1 118 ? 66.064  -9.586  43.798  1.00 28.56  ? 118 GLN E CG  1 
ATOM   13516 C CD  . GLN E 1 118 ? 67.551  -9.851  44.051  1.00 30.14  ? 118 GLN E CD  1 
ATOM   13517 O OE1 . GLN E 1 118 ? 67.911  -10.707 44.866  1.00 32.02  ? 118 GLN E OE1 1 
ATOM   13518 N NE2 . GLN E 1 118 ? 68.417  -9.124  43.339  1.00 32.43  ? 118 GLN E NE2 1 
ATOM   13519 N N   . LEU E 1 119 ? 62.758  -12.946 43.658  1.00 32.09  ? 119 LEU E N   1 
ATOM   13520 C CA  . LEU E 1 119 ? 62.089  -14.149 43.163  1.00 28.42  ? 119 LEU E CA  1 
ATOM   13521 C C   . LEU E 1 119 ? 60.738  -13.826 42.544  1.00 30.74  ? 119 LEU E C   1 
ATOM   13522 O O   . LEU E 1 119 ? 60.372  -14.402 41.512  1.00 32.05  ? 119 LEU E O   1 
ATOM   13523 C CB  . LEU E 1 119 ? 61.931  -15.173 44.292  1.00 32.84  ? 119 LEU E CB  1 
ATOM   13524 C CG  . LEU E 1 119 ? 61.471  -16.601 43.952  1.00 34.17  ? 119 LEU E CG  1 
ATOM   13525 C CD1 . LEU E 1 119 ? 62.408  -17.275 42.950  1.00 26.03  ? 119 LEU E CD1 1 
ATOM   13526 C CD2 . LEU E 1 119 ? 61.356  -17.459 45.238  1.00 29.88  ? 119 LEU E CD2 1 
ATOM   13527 N N   . THR E 1 120 ? 59.983  -12.895 43.139  1.00 30.78  ? 120 THR E N   1 
ATOM   13528 C CA  . THR E 1 120 ? 58.722  -12.492 42.519  1.00 28.17  ? 120 THR E CA  1 
ATOM   13529 C C   . THR E 1 120 ? 58.939  -11.765 41.197  1.00 37.90  ? 120 THR E C   1 
ATOM   13530 O O   . THR E 1 120 ? 58.002  -11.689 40.391  1.00 34.27  ? 120 THR E O   1 
ATOM   13531 C CB  . THR E 1 120 ? 57.869  -11.591 43.432  1.00 23.87  ? 120 THR E CB  1 
ATOM   13532 O OG1 . THR E 1 120 ? 58.464  -10.295 43.539  1.00 23.47  ? 120 THR E OG1 1 
ATOM   13533 C CG2 . THR E 1 120 ? 57.678  -12.185 44.818  1.00 24.95  ? 120 THR E CG2 1 
ATOM   13534 N N   . ARG E 1 121 ? 60.129  -11.199 40.960  1.00 36.37  ? 121 ARG E N   1 
ATOM   13535 C CA  . ARG E 1 121 ? 60.349  -10.593 39.649  1.00 37.70  ? 121 ARG E CA  1 
ATOM   13536 C C   . ARG E 1 121 ? 60.865  -11.601 38.629  1.00 36.07  ? 121 ARG E C   1 
ATOM   13537 O O   . ARG E 1 121 ? 60.473  -11.539 37.464  1.00 40.57  ? 121 ARG E O   1 
ATOM   13538 C CB  . ARG E 1 121 ? 61.307  -9.403  39.739  1.00 36.13  ? 121 ARG E CB  1 
ATOM   13539 C CG  . ARG E 1 121 ? 61.073  -8.382  38.627  1.00 37.44  ? 121 ARG E CG  1 
ATOM   13540 C CD  . ARG E 1 121 ? 61.682  -7.042  38.969  1.00 50.74  ? 121 ARG E CD  1 
ATOM   13541 N NE  . ARG E 1 121 ? 61.688  -6.107  37.847  1.00 62.14  ? 121 ARG E NE  1 
ATOM   13542 C CZ  . ARG E 1 121 ? 62.331  -6.290  36.699  1.00 63.72  ? 121 ARG E CZ  1 
ATOM   13543 N NH1 . ARG E 1 121 ? 63.056  -7.377  36.471  1.00 56.93  ? 121 ARG E NH1 1 
ATOM   13544 N NH2 . ARG E 1 121 ? 62.249  -5.355  35.755  1.00 62.96  ? 121 ARG E NH2 1 
ATOM   13545 N N   . LYS E 1 122 ? 61.717  -12.540 39.037  1.00 37.67  ? 122 LYS E N   1 
ATOM   13546 C CA  . LYS E 1 122 ? 62.155  -13.598 38.129  1.00 42.40  ? 122 LYS E CA  1 
ATOM   13547 C C   . LYS E 1 122 ? 60.950  -14.346 37.566  1.00 39.39  ? 122 LYS E C   1 
ATOM   13548 O O   . LYS E 1 122 ? 60.654  -14.218 36.375  1.00 48.09  ? 122 LYS E O   1 
ATOM   13549 C CB  . LYS E 1 122 ? 63.121  -14.558 38.826  1.00 41.23  ? 122 LYS E CB  1 
ATOM   13550 C CG  . LYS E 1 122 ? 64.514  -13.951 39.070  1.00 47.24  ? 122 LYS E CG  1 
ATOM   13551 C CD  . LYS E 1 122 ? 65.143  -13.455 37.780  1.00 44.51  ? 122 LYS E CD  1 
ATOM   13552 C CE  . LYS E 1 122 ? 66.576  -12.980 38.009  1.00 57.46  ? 122 LYS E CE  1 
ATOM   13553 N NZ  . LYS E 1 122 ? 67.313  -12.764 36.728  1.00 60.19  ? 122 LYS E NZ  1 
ATOM   13554 N N   . LEU E 1 123 ? 60.252  -15.124 38.390  1.00 37.88  ? 123 LEU E N   1 
ATOM   13555 C CA  . LEU E 1 123 ? 58.885  -15.503 38.054  1.00 37.71  ? 123 LEU E CA  1 
ATOM   13556 C C   . LEU E 1 123 ? 58.072  -14.232 37.828  1.00 40.87  ? 123 LEU E C   1 
ATOM   13557 O O   . LEU E 1 123 ? 58.394  -13.174 38.364  1.00 49.36  ? 123 LEU E O   1 
ATOM   13558 C CB  . LEU E 1 123 ? 58.297  -16.342 39.179  1.00 32.70  ? 123 LEU E CB  1 
ATOM   13559 C CG  . LEU E 1 123 ? 59.324  -17.249 39.869  1.00 37.59  ? 123 LEU E CG  1 
ATOM   13560 C CD1 . LEU E 1 123 ? 58.722  -17.897 41.115  1.00 32.16  ? 123 LEU E CD1 1 
ATOM   13561 C CD2 . LEU E 1 123 ? 59.852  -18.341 38.916  1.00 33.63  ? 123 LEU E CD2 1 
ATOM   13562 N N   . ASN E 1 124 ? 57.039  -14.297 36.999  1.00 43.56  ? 124 ASN E N   1 
ATOM   13563 C CA  . ASN E 1 124 ? 56.271  -13.060 36.783  1.00 38.86  ? 124 ASN E CA  1 
ATOM   13564 C C   . ASN E 1 124 ? 55.044  -13.024 37.692  1.00 39.44  ? 124 ASN E C   1 
ATOM   13565 O O   . ASN E 1 124 ? 53.907  -12.729 37.303  1.00 40.41  ? 124 ASN E O   1 
ATOM   13566 C CB  . ASN E 1 124 ? 55.900  -12.898 35.313  1.00 42.45  ? 124 ASN E CB  1 
ATOM   13567 C CG  . ASN E 1 124 ? 55.324  -11.524 34.999  1.00 45.69  ? 124 ASN E CG  1 
ATOM   13568 O OD1 . ASN E 1 124 ? 55.806  -10.505 35.492  1.00 50.92  ? 124 ASN E OD1 1 
ATOM   13569 N ND2 . ASN E 1 124 ? 54.285  -11.493 34.159  1.00 46.77  ? 124 ASN E ND2 1 
ATOM   13570 N N   . VAL E 1 125 ? 55.326  -13.320 38.955  1.00 32.13  ? 125 VAL E N   1 
ATOM   13571 C CA  . VAL E 1 125 ? 54.357  -13.463 40.028  1.00 34.01  ? 125 VAL E CA  1 
ATOM   13572 C C   . VAL E 1 125 ? 53.899  -12.082 40.507  1.00 35.51  ? 125 VAL E C   1 
ATOM   13573 O O   . VAL E 1 125 ? 54.494  -11.060 40.138  1.00 36.81  ? 125 VAL E O   1 
ATOM   13574 C CB  . VAL E 1 125 ? 55.023  -14.321 41.126  1.00 38.14  ? 125 VAL E CB  1 
ATOM   13575 C CG1 . VAL E 1 125 ? 54.773  -13.826 42.542  1.00 32.21  ? 125 VAL E CG1 1 
ATOM   13576 C CG2 . VAL E 1 125 ? 54.634  -15.780 40.958  1.00 35.89  ? 125 VAL E CG2 1 
ATOM   13577 N N   . ALA E 1 126 ? 52.796  -12.022 41.258  1.00 30.12  ? 126 ALA E N   1 
ATOM   13578 C CA  . ALA E 1 126 ? 52.393  -10.766 41.869  1.00 26.58  ? 126 ALA E CA  1 
ATOM   13579 C C   . ALA E 1 126 ? 53.538  -10.218 42.708  1.00 31.92  ? 126 ALA E C   1 
ATOM   13580 O O   . ALA E 1 126 ? 54.097  -10.924 43.551  1.00 34.83  ? 126 ALA E O   1 
ATOM   13581 C CB  . ALA E 1 126 ? 51.149  -10.962 42.734  1.00 32.80  ? 126 ALA E CB  1 
ATOM   13582 N N   . ALA E 1 127 ? 53.914  -8.968  42.445  1.00 33.80  ? 127 ALA E N   1 
ATOM   13583 C CA  . ALA E 1 127 ? 55.044  -8.366  43.133  1.00 34.72  ? 127 ALA E CA  1 
ATOM   13584 C C   . ALA E 1 127 ? 54.878  -8.499  44.643  1.00 27.09  ? 127 ALA E C   1 
ATOM   13585 O O   . ALA E 1 127 ? 53.814  -8.210  45.198  1.00 25.37  ? 127 ALA E O   1 
ATOM   13586 C CB  . ALA E 1 127 ? 55.186  -6.896  42.725  1.00 22.25  ? 127 ALA E CB  1 
ATOM   13587 N N   . LEU E 1 128 ? 55.928  -8.977  45.297  1.00 28.63  ? 128 LEU E N   1 
ATOM   13588 C CA  . LEU E 1 128 ? 55.949  -8.975  46.752  1.00 30.37  ? 128 LEU E CA  1 
ATOM   13589 C C   . LEU E 1 128 ? 55.518  -7.618  47.303  1.00 28.68  ? 128 LEU E C   1 
ATOM   13590 O O   . LEU E 1 128 ? 56.062  -6.573  46.923  1.00 24.63  ? 128 LEU E O   1 
ATOM   13591 C CB  . LEU E 1 128 ? 57.340  -9.330  47.251  1.00 27.35  ? 128 LEU E CB  1 
ATOM   13592 C CG  . LEU E 1 128 ? 57.233  -9.755  48.712  1.00 25.06  ? 128 LEU E CG  1 
ATOM   13593 C CD1 . LEU E 1 128 ? 56.980  -11.238 48.744  1.00 29.39  ? 128 LEU E CD1 1 
ATOM   13594 C CD2 . LEU E 1 128 ? 58.488  -9.398  49.463  1.00 27.52  ? 128 LEU E CD2 1 
ATOM   13595 N N   . ASP E 1 129 ? 54.503  -7.633  48.166  1.00 20.72  ? 129 ASP E N   1 
ATOM   13596 C CA  . ASP E 1 129 ? 54.093  -6.406  48.813  1.00 23.05  ? 129 ASP E CA  1 
ATOM   13597 C C   . ASP E 1 129 ? 55.277  -5.852  49.596  1.00 24.26  ? 129 ASP E C   1 
ATOM   13598 O O   . ASP E 1 129 ? 56.038  -6.601  50.220  1.00 23.04  ? 129 ASP E O   1 
ATOM   13599 C CB  . ASP E 1 129 ? 52.887  -6.652  49.728  1.00 27.83  ? 129 ASP E CB  1 
ATOM   13600 C CG  . ASP E 1 129 ? 52.141  -5.360  50.071  1.00 27.10  ? 129 ASP E CG  1 
ATOM   13601 O OD1 . ASP E 1 129 ? 52.381  -4.338  49.405  1.00 31.18  ? 129 ASP E OD1 1 
ATOM   13602 O OD2 . ASP E 1 129 ? 51.297  -5.361  50.987  1.00 30.59  ? 129 ASP E OD2 1 
ATOM   13603 N N   . GLY E 1 130 ? 55.456  -4.544  49.522  1.00 19.23  ? 130 GLY E N   1 
ATOM   13604 C CA  . GLY E 1 130 ? 56.612  -3.919  50.137  1.00 27.43  ? 130 GLY E CA  1 
ATOM   13605 C C   . GLY E 1 130 ? 57.908  -4.188  49.414  1.00 24.55  ? 130 GLY E C   1 
ATOM   13606 O O   . GLY E 1 130 ? 58.976  -4.114  50.029  1.00 25.51  ? 130 GLY E O   1 
ATOM   13607 N N   . TYR E 1 131 ? 57.829  -4.508  48.121  1.00 22.59  ? 131 TYR E N   1 
ATOM   13608 C CA  . TYR E 1 131 ? 58.978  -4.902  47.309  1.00 22.42  ? 131 TYR E CA  1 
ATOM   13609 C C   . TYR E 1 131 ? 60.225  -4.041  47.542  1.00 24.55  ? 131 TYR E C   1 
ATOM   13610 O O   . TYR E 1 131 ? 61.313  -4.572  47.797  1.00 27.41  ? 131 TYR E O   1 
ATOM   13611 C CB  . TYR E 1 131 ? 58.550  -4.857  45.837  1.00 23.50  ? 131 TYR E CB  1 
ATOM   13612 C CG  . TYR E 1 131 ? 59.659  -5.131  44.840  1.00 29.71  ? 131 TYR E CG  1 
ATOM   13613 C CD1 . TYR E 1 131 ? 59.998  -6.442  44.486  1.00 28.81  ? 131 TYR E CD1 1 
ATOM   13614 C CD2 . TYR E 1 131 ? 60.344  -4.080  44.224  1.00 21.57  ? 131 TYR E CD2 1 
ATOM   13615 C CE1 . TYR E 1 131 ? 61.017  -6.699  43.559  1.00 25.31  ? 131 TYR E CE1 1 
ATOM   13616 C CE2 . TYR E 1 131 ? 61.351  -4.327  43.303  1.00 31.32  ? 131 TYR E CE2 1 
ATOM   13617 C CZ  . TYR E 1 131 ? 61.683  -5.633  42.972  1.00 28.46  ? 131 TYR E CZ  1 
ATOM   13618 O OH  . TYR E 1 131 ? 62.685  -5.863  42.061  1.00 33.99  ? 131 TYR E OH  1 
ATOM   13619 N N   . GLU E 1 132 ? 60.082  -2.708  47.484  1.00 23.38  ? 132 GLU E N   1 
ATOM   13620 C CA  . GLU E 1 132 ? 61.257  -1.832  47.560  1.00 24.41  ? 132 GLU E CA  1 
ATOM   13621 C C   . GLU E 1 132 ? 61.893  -1.853  48.944  1.00 21.78  ? 132 GLU E C   1 
ATOM   13622 O O   . GLU E 1 132 ? 63.124  -1.810  49.064  1.00 24.23  ? 132 GLU E O   1 
ATOM   13623 C CB  . GLU E 1 132 ? 60.893  -0.389  47.182  1.00 25.11  ? 132 GLU E CB  1 
ATOM   13624 C CG  . GLU E 1 132 ? 60.426  -0.159  45.729  1.00 28.31  ? 132 GLU E CG  1 
ATOM   13625 C CD  . GLU E 1 132 ? 61.479  -0.518  44.682  1.00 31.09  ? 132 GLU E CD  1 
ATOM   13626 O OE1 . GLU E 1 132 ? 62.669  -0.700  45.036  1.00 38.33  ? 132 GLU E OE1 1 
ATOM   13627 O OE2 . GLU E 1 132 ? 61.118  -0.623  43.494  1.00 35.17  ? 132 GLU E OE2 1 
ATOM   13628 N N   . PHE E 1 133 ? 61.078  -1.867  50.001  1.00 21.21  ? 133 PHE E N   1 
ATOM   13629 C CA  . PHE E 1 133 ? 61.607  -2.041  51.352  1.00 22.66  ? 133 PHE E CA  1 
ATOM   13630 C C   . PHE E 1 133 ? 62.396  -3.338  51.461  1.00 24.07  ? 133 PHE E C   1 
ATOM   13631 O O   . PHE E 1 133 ? 63.494  -3.366  52.036  1.00 17.76  ? 133 PHE E O   1 
ATOM   13632 C CB  . PHE E 1 133 ? 60.455  -2.025  52.357  1.00 23.29  ? 133 PHE E CB  1 
ATOM   13633 C CG  . PHE E 1 133 ? 60.876  -2.019  53.810  1.00 18.60  ? 133 PHE E CG  1 
ATOM   13634 C CD1 . PHE E 1 133 ? 61.408  -0.862  54.394  1.00 21.12  ? 133 PHE E CD1 1 
ATOM   13635 C CD2 . PHE E 1 133 ? 60.641  -3.130  54.618  1.00 19.76  ? 133 PHE E CD2 1 
ATOM   13636 C CE1 . PHE E 1 133 ? 61.751  -0.833  55.757  1.00 24.50  ? 133 PHE E CE1 1 
ATOM   13637 C CE2 . PHE E 1 133 ? 60.980  -3.120  55.983  1.00 22.67  ? 133 PHE E CE2 1 
ATOM   13638 C CZ  . PHE E 1 133 ? 61.533  -1.967  56.560  1.00 19.68  ? 133 PHE E CZ  1 
ATOM   13639 N N   . ALA E 1 134 ? 61.864  -4.421  50.880  1.00 24.52  ? 134 ALA E N   1 
ATOM   13640 C CA  . ALA E 1 134 ? 62.562  -5.705  50.922  1.00 21.57  ? 134 ALA E CA  1 
ATOM   13641 C C   . ALA E 1 134 ? 63.857  -5.668  50.110  1.00 21.15  ? 134 ALA E C   1 
ATOM   13642 O O   . ALA E 1 134 ? 64.858  -6.264  50.510  1.00 20.21  ? 134 ALA E O   1 
ATOM   13643 C CB  . ALA E 1 134 ? 61.640  -6.813  50.417  1.00 19.42  ? 134 ALA E CB  1 
ATOM   13644 N N   . MET E 1 135 ? 63.858  -4.964  48.977  1.00 20.08  ? 135 MET E N   1 
ATOM   13645 C CA  . MET E 1 135 ? 65.054  -4.892  48.146  1.00 22.78  ? 135 MET E CA  1 
ATOM   13646 C C   . MET E 1 135 ? 66.223  -4.258  48.892  1.00 23.53  ? 135 MET E C   1 
ATOM   13647 O O   . MET E 1 135 ? 67.382  -4.587  48.624  1.00 21.77  ? 135 MET E O   1 
ATOM   13648 C CB  . MET E 1 135 ? 64.743  -4.113  46.870  1.00 19.72  ? 135 MET E CB  1 
ATOM   13649 C CG  . MET E 1 135 ? 63.873  -4.889  45.887  1.00 27.14  ? 135 MET E CG  1 
ATOM   13650 S SD  . MET E 1 135 ? 64.608  -6.462  45.375  1.00 54.07  ? 135 MET E SD  1 
ATOM   13651 C CE  . MET E 1 135 ? 65.790  -5.905  44.175  1.00 26.68  ? 135 MET E CE  1 
ATOM   13652 N N   . GLN E 1 136 ? 65.940  -3.346  49.818  1.00 21.85  ? 136 GLN E N   1 
ATOM   13653 C CA  . GLN E 1 136 ? 66.944  -2.744  50.671  1.00 20.09  ? 136 GLN E CA  1 
ATOM   13654 C C   . GLN E 1 136 ? 67.144  -3.524  51.969  1.00 19.28  ? 136 GLN E C   1 
ATOM   13655 O O   . GLN E 1 136 ? 67.778  -3.012  52.888  1.00 20.39  ? 136 GLN E O   1 
ATOM   13656 C CB  . GLN E 1 136 ? 66.558  -1.297  50.995  1.00 17.35  ? 136 GLN E CB  1 
ATOM   13657 C CG  . GLN E 1 136 ? 66.440  -0.363  49.818  1.00 18.12  ? 136 GLN E CG  1 
ATOM   13658 C CD  . GLN E 1 136 ? 67.635  -0.419  48.880  1.00 18.91  ? 136 GLN E CD  1 
ATOM   13659 O OE1 . GLN E 1 136 ? 68.779  -0.251  49.294  1.00 19.30  ? 136 GLN E OE1 1 
ATOM   13660 N NE2 . GLN E 1 136 ? 67.370  -0.668  47.613  1.00 15.09  ? 136 GLN E NE2 1 
ATOM   13661 N N   . ASN E 1 137 ? 66.603  -4.735  52.066  1.00 19.50  ? 137 ASN E N   1 
ATOM   13662 C CA  . ASN E 1 137 ? 66.652  -5.552  53.281  1.00 22.80  ? 137 ASN E CA  1 
ATOM   13663 C C   . ASN E 1 137 ? 66.164  -4.779  54.508  1.00 21.44  ? 137 ASN E C   1 
ATOM   13664 O O   . ASN E 1 137 ? 66.780  -4.784  55.578  1.00 22.65  ? 137 ASN E O   1 
ATOM   13665 C CB  . ASN E 1 137 ? 68.052  -6.132  53.488  1.00 24.79  ? 137 ASN E CB  1 
ATOM   13666 C CG  . ASN E 1 137 ? 68.335  -7.337  52.556  1.00 30.80  ? 137 ASN E CG  1 
ATOM   13667 O OD1 . ASN E 1 137 ? 67.582  -8.337  52.524  1.00 26.82  ? 137 ASN E OD1 1 
ATOM   13668 N ND2 . ASN E 1 137 ? 69.425  -7.240  51.793  1.00 27.30  ? 137 ASN E ND2 1 
ATOM   13669 N N   . GLY E 1 138 ? 65.016  -4.120  54.344  1.00 21.18  ? 138 GLY E N   1 
ATOM   13670 C CA  . GLY E 1 138 ? 64.425  -3.376  55.443  1.00 20.68  ? 138 GLY E CA  1 
ATOM   13671 C C   . GLY E 1 138 ? 64.090  -4.223  56.657  1.00 25.60  ? 138 GLY E C   1 
ATOM   13672 O O   . GLY E 1 138 ? 64.128  -3.730  57.785  1.00 25.05  ? 138 GLY E O   1 
ATOM   13673 N N   . ILE E 1 139 ? 63.755  -5.503  56.460  1.00 20.88  ? 139 ILE E N   1 
ATOM   13674 C CA  . ILE E 1 139 ? 63.348  -6.281  57.623  1.00 25.00  ? 139 ILE E CA  1 
ATOM   13675 C C   . ILE E 1 139 ? 64.560  -6.702  58.460  1.00 29.93  ? 139 ILE E C   1 
ATOM   13676 O O   . ILE E 1 139 ? 64.402  -7.009  59.647  1.00 29.11  ? 139 ILE E O   1 
ATOM   13677 C CB  . ILE E 1 139 ? 62.471  -7.486  57.221  1.00 31.02  ? 139 ILE E CB  1 
ATOM   13678 C CG1 . ILE E 1 139 ? 63.312  -8.596  56.634  1.00 30.31  ? 139 ILE E CG1 1 
ATOM   13679 C CG2 . ILE E 1 139 ? 61.398  -7.100  56.188  1.00 24.42  ? 139 ILE E CG2 1 
ATOM   13680 C CD1 . ILE E 1 139 ? 63.695  -9.579  57.642  1.00 39.67  ? 139 ILE E CD1 1 
ATOM   13681 N N   . ASP E 1 140 ? 65.765  -6.735  57.873  1.00 30.00  ? 140 ASP E N   1 
ATOM   13682 C CA  . ASP E 1 140 ? 66.997  -6.768  58.665  1.00 29.03  ? 140 ASP E CA  1 
ATOM   13683 C C   . ASP E 1 140 ? 67.034  -5.631  59.676  1.00 33.07  ? 140 ASP E C   1 
ATOM   13684 O O   . ASP E 1 140 ? 67.526  -5.797  60.798  1.00 29.60  ? 140 ASP E O   1 
ATOM   13685 C CB  . ASP E 1 140 ? 68.222  -6.670  57.747  1.00 27.96  ? 140 ASP E CB  1 
ATOM   13686 C CG  . ASP E 1 140 ? 68.572  -8.000  57.105  1.00 40.95  ? 140 ASP E CG  1 
ATOM   13687 O OD1 . ASP E 1 140 ? 68.430  -9.038  57.797  1.00 44.98  ? 140 ASP E OD1 1 
ATOM   13688 O OD2 . ASP E 1 140 ? 68.960  -8.012  55.906  1.00 43.05  ? 140 ASP E OD2 1 
ATOM   13689 N N   . LEU E 1 141 ? 66.543  -4.454  59.274  1.00 25.67  ? 141 LEU E N   1 
ATOM   13690 C CA  . LEU E 1 141 ? 66.495  -3.317  60.175  1.00 24.48  ? 141 LEU E CA  1 
ATOM   13691 C C   . LEU E 1 141 ? 65.501  -3.558  61.302  1.00 29.46  ? 141 LEU E C   1 
ATOM   13692 O O   . LEU E 1 141 ? 65.837  -3.398  62.478  1.00 25.69  ? 141 LEU E O   1 
ATOM   13693 C CB  . LEU E 1 141 ? 66.134  -2.060  59.388  1.00 24.01  ? 141 LEU E CB  1 
ATOM   13694 C CG  . LEU E 1 141 ? 66.106  -0.764  60.172  1.00 30.32  ? 141 LEU E CG  1 
ATOM   13695 C CD1 . LEU E 1 141 ? 67.466  -0.503  60.775  1.00 30.07  ? 141 LEU E CD1 1 
ATOM   13696 C CD2 . LEU E 1 141 ? 65.624  0.390   59.290  1.00 25.36  ? 141 LEU E CD2 1 
ATOM   13697 N N   . LEU E 1 142 ? 64.277  -3.974  60.957  1.00 27.79  ? 142 LEU E N   1 
ATOM   13698 C CA  . LEU E 1 142 ? 63.234  -4.156  61.958  1.00 24.24  ? 142 LEU E CA  1 
ATOM   13699 C C   . LEU E 1 142 ? 63.543  -5.309  62.917  1.00 30.35  ? 142 LEU E C   1 
ATOM   13700 O O   . LEU E 1 142 ? 63.144  -5.263  64.089  1.00 30.83  ? 142 LEU E O   1 
ATOM   13701 C CB  . LEU E 1 142 ? 61.894  -4.387  61.265  1.00 23.24  ? 142 LEU E CB  1 
ATOM   13702 C CG  . LEU E 1 142 ? 61.486  -3.268  60.296  1.00 24.78  ? 142 LEU E CG  1 
ATOM   13703 C CD1 . LEU E 1 142 ? 60.203  -3.592  59.571  1.00 23.50  ? 142 LEU E CD1 1 
ATOM   13704 C CD2 . LEU E 1 142 ? 61.358  -1.983  61.048  1.00 21.58  ? 142 LEU E CD2 1 
ATOM   13705 N N   . ASN E 1 143 ? 64.271  -6.329  62.468  1.00 24.19  ? 143 ASN E N   1 
ATOM   13706 C CA  . ASN E 1 143 ? 64.481  -7.504  63.296  1.00 25.33  ? 143 ASN E CA  1 
ATOM   13707 C C   . ASN E 1 143 ? 65.701  -7.397  64.190  1.00 25.09  ? 143 ASN E C   1 
ATOM   13708 O O   . ASN E 1 143 ? 66.249  -8.424  64.586  1.00 32.49  ? 143 ASN E O   1 
ATOM   13709 C CB  . ASN E 1 143 ? 64.572  -8.756  62.420  1.00 24.32  ? 143 ASN E CB  1 
ATOM   13710 C CG  . ASN E 1 143 ? 63.213  -9.159  61.869  1.00 29.74  ? 143 ASN E CG  1 
ATOM   13711 O OD1 . ASN E 1 143 ? 62.173  -8.901  62.493  1.00 31.76  ? 143 ASN E OD1 1 
ATOM   13712 N ND2 . ASN E 1 143 ? 63.206  -9.780  60.706  1.00 28.68  ? 143 ASN E ND2 1 
ATOM   13713 N N   . MET E 1 144 ? 66.161  -6.192  64.489  1.00 25.72  ? 144 MET E N   1 
ATOM   13714 C CA  . MET E 1 144 ? 67.215  -5.992  65.471  1.00 28.12  ? 144 MET E CA  1 
ATOM   13715 C C   . MET E 1 144 ? 66.612  -5.541  66.795  1.00 23.62  ? 144 MET E C   1 
ATOM   13716 O O   . MET E 1 144 ? 65.648  -4.769  66.824  1.00 21.10  ? 144 MET E O   1 
ATOM   13717 C CB  . MET E 1 144 ? 68.232  -4.966  64.981  1.00 27.82  ? 144 MET E CB  1 
ATOM   13718 C CG  . MET E 1 144 ? 69.068  -5.444  63.815  1.00 31.77  ? 144 MET E CG  1 
ATOM   13719 S SD  . MET E 1 144 ? 69.563  -4.048  62.824  1.00 33.02  ? 144 MET E SD  1 
ATOM   13720 C CE  . MET E 1 144 ? 71.049  -3.582  63.741  1.00 30.01  ? 144 MET E CE  1 
ATOM   13721 N N   . LYS E 1 145 ? 67.174  -6.033  67.895  1.00 26.12  ? 145 LYS E N   1 
ATOM   13722 C CA  . LYS E 1 145 ? 66.631  -5.618  69.186  1.00 25.46  ? 145 LYS E CA  1 
ATOM   13723 C C   . LYS E 1 145 ? 66.943  -4.151  69.452  1.00 23.92  ? 145 LYS E C   1 
ATOM   13724 O O   . LYS E 1 145 ? 66.126  -3.441  70.052  1.00 23.47  ? 145 LYS E O   1 
ATOM   13725 C CB  . LYS E 1 145 ? 67.173  -6.507  70.305  1.00 29.23  ? 145 LYS E CB  1 
ATOM   13726 C CG  . LYS E 1 145 ? 67.063  -8.016  70.028  1.00 31.35  ? 145 LYS E CG  1 
ATOM   13727 C CD  . LYS E 1 145 ? 66.145  -8.680  71.014  1.00 30.19  ? 145 LYS E CD  1 
ATOM   13728 C CE  . LYS E 1 145 ? 66.076  -10.176 70.789  1.00 41.81  ? 145 LYS E CE  1 
ATOM   13729 N NZ  . LYS E 1 145 ? 67.384  -10.791 70.385  1.00 36.59  ? 145 LYS E NZ  1 
ATOM   13730 N N   . SER E 1 146 ? 68.097  -3.678  68.975  1.00 21.66  ? 146 SER E N   1 
ATOM   13731 C CA  . SER E 1 146 ? 68.440  -2.261  69.101  1.00 27.35  ? 146 SER E CA  1 
ATOM   13732 C C   . SER E 1 146 ? 67.396  -1.368  68.432  1.00 25.93  ? 146 SER E C   1 
ATOM   13733 O O   . SER E 1 146 ? 66.952  -0.364  69.016  1.00 25.88  ? 146 SER E O   1 
ATOM   13734 C CB  . SER E 1 146 ? 69.828  -2.006  68.503  1.00 27.05  ? 146 SER E CB  1 
ATOM   13735 O OG  . SER E 1 146 ? 70.000  -2.723  67.293  1.00 27.73  ? 146 SER E OG  1 
ATOM   13736 N N   . THR E 1 147 ? 66.979  -1.725  67.220  1.00 20.12  ? 147 THR E N   1 
ATOM   13737 C CA  . THR E 1 147 ? 65.956  -0.949  66.526  1.00 20.07  ? 147 THR E CA  1 
ATOM   13738 C C   . THR E 1 147 ? 64.656  -0.914  67.313  1.00 20.74  ? 147 THR E C   1 
ATOM   13739 O O   . THR E 1 147 ? 64.039  0.148   67.468  1.00 20.75  ? 147 THR E O   1 
ATOM   13740 C CB  . THR E 1 147 ? 65.702  -1.532  65.147  1.00 17.70  ? 147 THR E CB  1 
ATOM   13741 O OG1 . THR E 1 147 ? 66.925  -1.543  64.414  1.00 18.80  ? 147 THR E OG1 1 
ATOM   13742 C CG2 . THR E 1 147 ? 64.665  -0.707  64.425  1.00 17.00  ? 147 THR E CG2 1 
ATOM   13743 N N   . PHE E 1 148 ? 64.202  -2.070  67.806  1.00 21.53  ? 148 PHE E N   1 
ATOM   13744 C CA  . PHE E 1 148 ? 62.980  -2.039  68.597  1.00 19.90  ? 148 PHE E CA  1 
ATOM   13745 C C   . PHE E 1 148 ? 63.111  -1.053  69.747  1.00 18.15  ? 148 PHE E C   1 
ATOM   13746 O O   . PHE E 1 148 ? 62.265  -0.176  69.927  1.00 21.85  ? 148 PHE E O   1 
ATOM   13747 C CB  . PHE E 1 148 ? 62.616  -3.425  69.126  1.00 19.01  ? 148 PHE E CB  1 
ATOM   13748 C CG  . PHE E 1 148 ? 61.413  -3.392  70.017  1.00 23.51  ? 148 PHE E CG  1 
ATOM   13749 C CD1 . PHE E 1 148 ? 60.161  -3.147  69.481  1.00 21.46  ? 148 PHE E CD1 1 
ATOM   13750 C CD2 . PHE E 1 148 ? 61.541  -3.511  71.390  1.00 22.42  ? 148 PHE E CD2 1 
ATOM   13751 C CE1 . PHE E 1 148 ? 59.058  -3.061  70.278  1.00 22.92  ? 148 PHE E CE1 1 
ATOM   13752 C CE2 . PHE E 1 148 ? 60.430  -3.431  72.205  1.00 26.13  ? 148 PHE E CE2 1 
ATOM   13753 C CZ  . PHE E 1 148 ? 59.185  -3.211  71.651  1.00 25.35  ? 148 PHE E CZ  1 
ATOM   13754 N N   . ARG E 1 149 ? 64.178  -1.174  70.537  1.00 19.91  ? 149 ARG E N   1 
ATOM   13755 C CA  . ARG E 1 149 ? 64.321  -0.294  71.690  1.00 24.31  ? 149 ARG E CA  1 
ATOM   13756 C C   . ARG E 1 149 ? 64.286  1.173   71.266  1.00 23.45  ? 149 ARG E C   1 
ATOM   13757 O O   . ARG E 1 149 ? 63.697  2.010   71.958  1.00 21.78  ? 149 ARG E O   1 
ATOM   13758 C CB  . ARG E 1 149 ? 65.619  -0.626  72.455  1.00 25.75  ? 149 ARG E CB  1 
ATOM   13759 C CG  . ARG E 1 149 ? 65.479  -1.856  73.414  1.00 25.91  ? 149 ARG E CG  1 
ATOM   13760 C CD  . ARG E 1 149 ? 66.509  -1.890  74.547  1.00 26.66  ? 149 ARG E CD  1 
ATOM   13761 N NE  . ARG E 1 149 ? 66.284  -0.794  75.481  1.00 22.94  ? 149 ARG E NE  1 
ATOM   13762 C CZ  . ARG E 1 149 ? 65.406  -0.823  76.477  1.00 28.61  ? 149 ARG E CZ  1 
ATOM   13763 N NH1 . ARG E 1 149 ? 64.728  -1.924  76.771  1.00 25.11  ? 149 ARG E NH1 1 
ATOM   13764 N NH2 . ARG E 1 149 ? 65.213  0.274   77.207  1.00 21.69  ? 149 ARG E NH2 1 
ATOM   13765 N N   . ARG E 1 150 ? 64.879  1.492   70.111  1.00 20.33  ? 150 ARG E N   1 
ATOM   13766 C CA  . ARG E 1 150 ? 64.984  2.879   69.672  1.00 18.67  ? 150 ARG E CA  1 
ATOM   13767 C C   . ARG E 1 150 ? 63.641  3.407   69.192  1.00 22.36  ? 150 ARG E C   1 
ATOM   13768 O O   . ARG E 1 150 ? 63.192  4.471   69.626  1.00 22.71  ? 150 ARG E O   1 
ATOM   13769 C CB  . ARG E 1 150 ? 66.014  3.000   68.552  1.00 21.03  ? 150 ARG E CB  1 
ATOM   13770 C CG  . ARG E 1 150 ? 67.403  2.918   69.031  1.00 22.09  ? 150 ARG E CG  1 
ATOM   13771 C CD  . ARG E 1 150 ? 68.343  2.536   67.921  1.00 24.03  ? 150 ARG E CD  1 
ATOM   13772 N NE  . ARG E 1 150 ? 69.710  2.504   68.416  1.00 22.08  ? 150 ARG E NE  1 
ATOM   13773 C CZ  . ARG E 1 150 ? 70.753  2.120   67.701  1.00 27.80  ? 150 ARG E CZ  1 
ATOM   13774 N NH1 . ARG E 1 150 ? 70.613  1.657   66.467  1.00 27.16  ? 150 ARG E NH1 1 
ATOM   13775 N NH2 . ARG E 1 150 ? 71.968  2.218   68.230  1.00 29.49  ? 150 ARG E NH2 1 
ATOM   13776 N N   . LEU E 1 151 ? 62.989  2.676   68.283  1.00 21.27  ? 151 LEU E N   1 
ATOM   13777 C CA  . LEU E 1 151 ? 61.651  3.064   67.865  1.00 21.74  ? 151 LEU E CA  1 
ATOM   13778 C C   . LEU E 1 151 ? 60.698  3.105   69.048  1.00 21.96  ? 151 LEU E C   1 
ATOM   13779 O O   . LEU E 1 151 ? 59.890  4.034   69.162  1.00 27.35  ? 151 LEU E O   1 
ATOM   13780 C CB  . LEU E 1 151 ? 61.123  2.107   66.793  1.00 22.26  ? 151 LEU E CB  1 
ATOM   13781 C CG  . LEU E 1 151 ? 61.975  2.024   65.520  1.00 26.64  ? 151 LEU E CG  1 
ATOM   13782 C CD1 . LEU E 1 151 ? 61.313  1.133   64.480  1.00 25.17  ? 151 LEU E CD1 1 
ATOM   13783 C CD2 . LEU E 1 151 ? 62.238  3.393   64.963  1.00 23.98  ? 151 LEU E CD2 1 
ATOM   13784 N N   . ALA E 1 152 ? 60.758  2.102   69.934  1.00 19.13  ? 152 ALA E N   1 
ATOM   13785 C CA  . ALA E 1 152 ? 59.846  2.113   71.081  1.00 21.58  ? 152 ALA E CA  1 
ATOM   13786 C C   . ALA E 1 152 ? 60.128  3.310   71.978  1.00 22.51  ? 152 ALA E C   1 
ATOM   13787 O O   . ALA E 1 152 ? 59.205  4.022   72.384  1.00 19.40  ? 152 ALA E O   1 
ATOM   13788 C CB  . ALA E 1 152 ? 59.939  0.807   71.873  1.00 23.11  ? 152 ALA E CB  1 
ATOM   13789 N N   . ALA E 1 153 ? 61.410  3.568   72.262  1.00 20.19  ? 153 ALA E N   1 
ATOM   13790 C CA  . ALA E 1 153 ? 61.761  4.751   73.031  1.00 20.18  ? 153 ALA E CA  1 
ATOM   13791 C C   . ALA E 1 153 ? 61.375  6.011   72.281  1.00 23.76  ? 153 ALA E C   1 
ATOM   13792 O O   . ALA E 1 153 ? 60.888  6.971   72.881  1.00 17.85  ? 153 ALA E O   1 
ATOM   13793 C CB  . ALA E 1 153 ? 63.255  4.754   73.347  1.00 19.76  ? 153 ALA E CB  1 
ATOM   13794 N N   . GLY E 1 154 ? 61.568  6.020   70.961  1.00 26.62  ? 154 GLY E N   1 
ATOM   13795 C CA  . GLY E 1 154 ? 61.161  7.177   70.186  1.00 22.74  ? 154 GLY E CA  1 
ATOM   13796 C C   . GLY E 1 154 ? 59.666  7.420   70.240  1.00 27.52  ? 154 GLY E C   1 
ATOM   13797 O O   . GLY E 1 154 ? 59.217  8.569   70.303  1.00 29.56  ? 154 GLY E O   1 
ATOM   13798 N N   . LEU E 1 155 ? 58.871  6.343   70.231  1.00 26.70  ? 155 LEU E N   1 
ATOM   13799 C CA  . LEU E 1 155 ? 57.421  6.487   70.118  1.00 25.41  ? 155 LEU E CA  1 
ATOM   13800 C C   . LEU E 1 155 ? 56.734  6.714   71.452  1.00 28.91  ? 155 LEU E C   1 
ATOM   13801 O O   . LEU E 1 155 ? 55.652  7.310   71.482  1.00 27.96  ? 155 LEU E O   1 
ATOM   13802 C CB  . LEU E 1 155 ? 56.780  5.241   69.499  1.00 25.13  ? 155 LEU E CB  1 
ATOM   13803 C CG  . LEU E 1 155 ? 55.953  5.287   68.215  1.00 34.05  ? 155 LEU E CG  1 
ATOM   13804 C CD1 . LEU E 1 155 ? 55.249  3.939   68.028  1.00 27.11  ? 155 LEU E CD1 1 
ATOM   13805 C CD2 . LEU E 1 155 ? 54.949  6.417   68.216  1.00 35.90  ? 155 LEU E CD2 1 
ATOM   13806 N N   . GLY E 1 156 ? 57.311  6.223   72.543  1.00 25.47  ? 156 GLY E N   1 
ATOM   13807 C CA  . GLY E 1 156 ? 56.609  6.144   73.806  1.00 26.95  ? 156 GLY E CA  1 
ATOM   13808 C C   . GLY E 1 156 ? 55.995  4.795   74.113  1.00 29.40  ? 156 GLY E C   1 
ATOM   13809 O O   . GLY E 1 156 ? 55.212  4.691   75.067  1.00 31.87  ? 156 GLY E O   1 
ATOM   13810 N N   . THR E 1 157 ? 56.311  3.764   73.341  1.00 24.98  ? 157 THR E N   1 
ATOM   13811 C CA  . THR E 1 157 ? 55.828  2.437   73.676  1.00 27.76  ? 157 THR E CA  1 
ATOM   13812 C C   . THR E 1 157 ? 56.416  1.995   75.018  1.00 28.81  ? 157 THR E C   1 
ATOM   13813 O O   . THR E 1 157 ? 57.594  2.233   75.279  1.00 27.39  ? 157 THR E O   1 
ATOM   13814 C CB  . THR E 1 157 ? 56.198  1.455   72.565  1.00 25.57  ? 157 THR E CB  1 
ATOM   13815 O OG1 . THR E 1 157 ? 55.765  1.987   71.301  1.00 30.57  ? 157 THR E OG1 1 
ATOM   13816 C CG2 . THR E 1 157 ? 55.523  0.132   72.780  1.00 26.13  ? 157 THR E CG2 1 
ATOM   13817 N N   . PRO E 1 158 ? 55.626  1.369   75.895  1.00 28.19  ? 158 PRO E N   1 
ATOM   13818 C CA  . PRO E 1 158 ? 56.159  0.937   77.201  1.00 27.25  ? 158 PRO E CA  1 
ATOM   13819 C C   . PRO E 1 158 ? 57.312  -0.044  77.049  1.00 26.16  ? 158 PRO E C   1 
ATOM   13820 O O   . PRO E 1 158 ? 57.177  -1.091  76.418  1.00 27.12  ? 158 PRO E O   1 
ATOM   13821 C CB  . PRO E 1 158 ? 54.954  0.280   77.886  1.00 29.42  ? 158 PRO E CB  1 
ATOM   13822 C CG  . PRO E 1 158 ? 53.753  0.789   77.157  1.00 29.06  ? 158 PRO E CG  1 
ATOM   13823 C CD  . PRO E 1 158 ? 54.186  1.084   75.754  1.00 27.07  ? 158 PRO E CD  1 
ATOM   13824 N N   . LEU E 1 159 ? 58.443  0.286   77.683  1.00 29.34  ? 159 LEU E N   1 
ATOM   13825 C CA  . LEU E 1 159 ? 59.726  -0.350  77.423  1.00 26.10  ? 159 LEU E CA  1 
ATOM   13826 C C   . LEU E 1 159 ? 60.500  -0.496  78.726  1.00 26.70  ? 159 LEU E C   1 
ATOM   13827 O O   . LEU E 1 159 ? 60.553  0.438   79.520  1.00 27.89  ? 159 LEU E O   1 
ATOM   13828 C CB  . LEU E 1 159 ? 60.516  0.501   76.422  1.00 25.88  ? 159 LEU E CB  1 
ATOM   13829 C CG  . LEU E 1 159 ? 61.728  -0.060  75.700  1.00 29.36  ? 159 LEU E CG  1 
ATOM   13830 C CD1 . LEU E 1 159 ? 61.368  -1.302  74.884  1.00 29.05  ? 159 LEU E CD1 1 
ATOM   13831 C CD2 . LEU E 1 159 ? 62.286  1.021   74.816  1.00 27.19  ? 159 LEU E CD2 1 
ATOM   13832 N N   . THR E 1 160 ? 61.101  -1.661  78.957  1.00 27.92  ? 160 THR E N   1 
ATOM   13833 C CA  . THR E 1 160 ? 61.866  -1.828  80.187  1.00 30.10  ? 160 THR E CA  1 
ATOM   13834 C C   . THR E 1 160 ? 63.100  -0.923  80.177  1.00 27.40  ? 160 THR E C   1 
ATOM   13835 O O   . THR E 1 160 ? 63.586  -0.511  79.122  1.00 27.67  ? 160 THR E O   1 
ATOM   13836 C CB  . THR E 1 160 ? 62.301  -3.288  80.372  1.00 32.51  ? 160 THR E CB  1 
ATOM   13837 O OG1 . THR E 1 160 ? 63.348  -3.610  79.440  1.00 31.51  ? 160 THR E OG1 1 
ATOM   13838 C CG2 . THR E 1 160 ? 61.127  -4.229  80.139  1.00 30.45  ? 160 THR E CG2 1 
ATOM   13839 N N   . ASP E 1 161 ? 63.592  -0.598  81.373  1.00 26.03  ? 161 ASP E N   1 
ATOM   13840 C CA  . ASP E 1 161 ? 64.893  0.063   81.514  1.00 29.74  ? 161 ASP E CA  1 
ATOM   13841 C C   . ASP E 1 161 ? 65.964  -0.728  80.775  1.00 28.37  ? 161 ASP E C   1 
ATOM   13842 O O   . ASP E 1 161 ? 66.165  -1.916  81.058  1.00 28.48  ? 161 ASP E O   1 
ATOM   13843 C CB  . ASP E 1 161 ? 65.280  0.153   82.995  1.00 40.08  ? 161 ASP E CB  1 
ATOM   13844 C CG  . ASP E 1 161 ? 64.636  1.313   83.724  1.00 48.64  ? 161 ASP E CG  1 
ATOM   13845 O OD1 . ASP E 1 161 ? 63.411  1.524   83.573  1.00 47.83  ? 161 ASP E OD1 1 
ATOM   13846 O OD2 . ASP E 1 161 ? 65.370  1.995   84.481  1.00 49.28  ? 161 ASP E OD2 1 
ATOM   13847 N N   . GLY E 1 162 ? 66.686  -0.079  79.863  1.00 27.16  ? 162 GLY E N   1 
ATOM   13848 C CA  . GLY E 1 162 ? 67.711  -0.818  79.137  1.00 25.69  ? 162 GLY E CA  1 
ATOM   13849 C C   . GLY E 1 162 ? 68.682  0.074   78.390  1.00 25.78  ? 162 GLY E C   1 
ATOM   13850 O O   . GLY E 1 162 ? 68.504  1.291   78.279  1.00 24.40  ? 162 GLY E O   1 
ATOM   13851 N N   . VAL E 1 163 ? 69.721  -0.563  77.862  1.00 25.57  ? 163 VAL E N   1 
ATOM   13852 C CA  . VAL E 1 163 ? 70.733  0.120   77.067  1.00 25.72  ? 163 VAL E CA  1 
ATOM   13853 C C   . VAL E 1 163 ? 70.942  -0.656  75.773  1.00 27.04  ? 163 VAL E C   1 
ATOM   13854 O O   . VAL E 1 163 ? 70.804  -1.884  75.731  1.00 25.28  ? 163 VAL E O   1 
ATOM   13855 C CB  . VAL E 1 163 ? 72.059  0.259   77.857  1.00 25.63  ? 163 VAL E CB  1 
ATOM   13856 C CG1 . VAL E 1 163 ? 73.204  0.755   76.975  1.00 31.19  ? 163 VAL E CG1 1 
ATOM   13857 C CG2 . VAL E 1 163 ? 71.867  1.169   79.063  1.00 23.87  ? 163 VAL E CG2 1 
ATOM   13858 N N   . VAL E 1 164 ? 71.248  0.074   74.701  1.00 28.50  ? 164 VAL E N   1 
ATOM   13859 C CA  . VAL E 1 164 ? 71.804  -0.515  73.491  1.00 22.18  ? 164 VAL E CA  1 
ATOM   13860 C C   . VAL E 1 164 ? 73.321  -0.393  73.622  1.00 26.98  ? 164 VAL E C   1 
ATOM   13861 O O   . VAL E 1 164 ? 73.892  0.655   73.331  1.00 25.31  ? 164 VAL E O   1 
ATOM   13862 C CB  . VAL E 1 164 ? 71.284  0.174   72.231  1.00 23.39  ? 164 VAL E CB  1 
ATOM   13863 C CG1 . VAL E 1 164 ? 71.968  -0.401  71.007  1.00 22.08  ? 164 VAL E CG1 1 
ATOM   13864 C CG2 . VAL E 1 164 ? 69.750  0.038   72.126  1.00 22.57  ? 164 VAL E CG2 1 
ATOM   13865 N N   . ALA E 1 165 ? 73.979  -1.482  74.048  1.00 27.30  ? 165 ALA E N   1 
ATOM   13866 C CA  . ALA E 1 165 ? 75.381  -1.449  74.453  1.00 27.93  ? 165 ALA E CA  1 
ATOM   13867 C C   . ALA E 1 165 ? 76.309  -1.720  73.277  1.00 27.67  ? 165 ALA E C   1 
ATOM   13868 O O   . ALA E 1 165 ? 76.101  -2.663  72.513  1.00 31.43  ? 165 ALA E O   1 
ATOM   13869 C CB  . ALA E 1 165 ? 75.650  -2.468  75.566  1.00 29.14  ? 165 ALA E CB  1 
ATOM   13870 N N   . ARG E 1 166 ? 77.361  -0.913  73.168  1.00 23.07  ? 166 ARG E N   1 
ATOM   13871 C CA  . ARG E 1 166 ? 78.223  -0.892  71.993  1.00 33.87  ? 166 ARG E CA  1 
ATOM   13872 C C   . ARG E 1 166 ? 79.605  -1.468  72.249  1.00 34.74  ? 166 ARG E C   1 
ATOM   13873 O O   . ARG E 1 166 ? 80.423  -1.529  71.321  1.00 33.58  ? 166 ARG E O   1 
ATOM   13874 C CB  . ARG E 1 166 ? 78.366  0.544   71.459  1.00 31.48  ? 166 ARG E CB  1 
ATOM   13875 C CG  . ARG E 1 166 ? 77.109  1.063   70.776  1.00 36.99  ? 166 ARG E CG  1 
ATOM   13876 C CD  . ARG E 1 166 ? 77.058  2.573   70.727  1.00 36.98  ? 166 ARG E CD  1 
ATOM   13877 N NE  . ARG E 1 166 ? 77.006  3.154   72.060  1.00 36.27  ? 166 ARG E NE  1 
ATOM   13878 C CZ  . ARG E 1 166 ? 77.075  4.455   72.299  1.00 36.86  ? 166 ARG E CZ  1 
ATOM   13879 N NH1 . ARG E 1 166 ? 77.127  5.336   71.312  1.00 42.75  ? 166 ARG E NH1 1 
ATOM   13880 N NH2 . ARG E 1 166 ? 77.081  4.884   73.556  1.00 33.90  ? 166 ARG E NH2 1 
ATOM   13881 N N   . GLY E 1 167 ? 79.887  -1.881  73.475  1.00 31.06  ? 167 GLY E N   1 
ATOM   13882 C CA  . GLY E 1 167 ? 81.140  -2.498  73.809  1.00 27.39  ? 167 GLY E CA  1 
ATOM   13883 C C   . GLY E 1 167 ? 81.037  -3.066  75.203  1.00 31.69  ? 167 GLY E C   1 
ATOM   13884 O O   . GLY E 1 167 ? 80.048  -2.845  75.914  1.00 30.06  ? 167 GLY E O   1 
ATOM   13885 N N   . PRO E 1 168 ? 82.056  -3.822  75.622  1.00 35.96  ? 168 PRO E N   1 
ATOM   13886 C CA  . PRO E 1 168 ? 82.007  -4.430  76.968  1.00 31.87  ? 168 PRO E CA  1 
ATOM   13887 C C   . PRO E 1 168 ? 82.053  -3.420  78.098  1.00 31.84  ? 168 PRO E C   1 
ATOM   13888 O O   . PRO E 1 168 ? 81.548  -3.716  79.187  1.00 32.60  ? 168 PRO E O   1 
ATOM   13889 C CB  . PRO E 1 168 ? 83.231  -5.355  77.000  1.00 30.20  ? 168 PRO E CB  1 
ATOM   13890 C CG  . PRO E 1 168 ? 84.056  -5.011  75.773  1.00 28.99  ? 168 PRO E CG  1 
ATOM   13891 C CD  . PRO E 1 168 ? 83.148  -4.350  74.786  1.00 28.33  ? 168 PRO E CD  1 
ATOM   13892 N N   . ALA E 1 169 ? 82.648  -2.242  77.899  1.00 35.34  ? 169 ALA E N   1 
ATOM   13893 C CA  . ALA E 1 169 ? 82.616  -1.257  78.978  1.00 36.29  ? 169 ALA E CA  1 
ATOM   13894 C C   . ALA E 1 169 ? 81.197  -0.737  79.200  1.00 37.01  ? 169 ALA E C   1 
ATOM   13895 O O   . ALA E 1 169 ? 80.800  -0.465  80.343  1.00 33.19  ? 169 ALA E O   1 
ATOM   13896 C CB  . ALA E 1 169 ? 83.583  -0.113  78.687  1.00 25.09  ? 169 ALA E CB  1 
ATOM   13897 N N   . GLU E 1 170 ? 80.411  -0.606  78.123  1.00 36.60  ? 170 GLU E N   1 
ATOM   13898 C CA  . GLU E 1 170 ? 79.013  -0.211  78.294  1.00 38.11  ? 170 GLU E CA  1 
ATOM   13899 C C   . GLU E 1 170 ? 78.197  -1.322  78.920  1.00 35.46  ? 170 GLU E C   1 
ATOM   13900 O O   . GLU E 1 170 ? 77.253  -1.039  79.666  1.00 31.97  ? 170 GLU E O   1 
ATOM   13901 C CB  . GLU E 1 170 ? 78.371  0.195   76.971  1.00 34.47  ? 170 GLU E CB  1 
ATOM   13902 C CG  . GLU E 1 170 ? 78.477  1.683   76.679  1.00 38.27  ? 170 GLU E CG  1 
ATOM   13903 C CD  . GLU E 1 170 ? 77.405  2.178   75.733  1.00 41.84  ? 170 GLU E CD  1 
ATOM   13904 O OE1 . GLU E 1 170 ? 77.564  2.014   74.497  1.00 41.99  ? 170 GLU E OE1 1 
ATOM   13905 O OE2 . GLU E 1 170 ? 76.419  2.765   76.233  1.00 38.75  ? 170 GLU E OE2 1 
ATOM   13906 N N   . VAL E 1 171 ? 78.539  -2.584  78.639  1.00 31.60  ? 171 VAL E N   1 
ATOM   13907 C CA  . VAL E 1 171 ? 77.855  -3.675  79.318  1.00 31.17  ? 171 VAL E CA  1 
ATOM   13908 C C   . VAL E 1 171 ? 78.129  -3.609  80.816  1.00 30.94  ? 171 VAL E C   1 
ATOM   13909 O O   . VAL E 1 171 ? 77.221  -3.789  81.637  1.00 30.45  ? 171 VAL E O   1 
ATOM   13910 C CB  . VAL E 1 171 ? 78.265  -5.026  78.715  1.00 27.77  ? 171 VAL E CB  1 
ATOM   13911 C CG1 . VAL E 1 171 ? 77.653  -6.165  79.505  1.00 27.37  ? 171 VAL E CG1 1 
ATOM   13912 C CG2 . VAL E 1 171 ? 77.819  -5.104  77.277  1.00 32.24  ? 171 VAL E CG2 1 
ATOM   13913 N N   . ARG E 1 172 ? 79.376  -3.310  81.188  1.00 32.42  ? 172 ARG E N   1 
ATOM   13914 C CA  . ARG E 1 172 ? 79.739  -3.136  82.593  1.00 39.26  ? 172 ARG E CA  1 
ATOM   13915 C C   . ARG E 1 172 ? 78.927  -2.020  83.252  1.00 34.07  ? 172 ARG E C   1 
ATOM   13916 O O   . ARG E 1 172 ? 78.321  -2.228  84.311  1.00 35.02  ? 172 ARG E O   1 
ATOM   13917 C CB  . ARG E 1 172 ? 81.240  -2.858  82.703  1.00 34.43  ? 172 ARG E CB  1 
ATOM   13918 C CG  . ARG E 1 172 ? 81.721  -2.605  84.112  1.00 43.06  ? 172 ARG E CG  1 
ATOM   13919 C CD  . ARG E 1 172 ? 83.238  -2.621  84.194  1.00 44.55  ? 172 ARG E CD  1 
ATOM   13920 N NE  . ARG E 1 172 ? 83.699  -2.409  85.561  1.00 56.71  ? 172 ARG E NE  1 
ATOM   13921 C CZ  . ARG E 1 172 ? 83.961  -1.221  86.088  1.00 60.02  ? 172 ARG E CZ  1 
ATOM   13922 N NH1 . ARG E 1 172 ? 83.829  -0.107  85.383  1.00 59.69  ? 172 ARG E NH1 1 
ATOM   13923 N NH2 . ARG E 1 172 ? 84.375  -1.148  87.351  1.00 57.85  ? 172 ARG E NH2 1 
ATOM   13924 N N   . SER E 1 173 ? 78.923  -0.820  82.649  1.00 33.52  ? 173 SER E N   1 
ATOM   13925 C CA  . SER E 1 173 ? 78.060  0.270   83.118  1.00 37.72  ? 173 SER E CA  1 
ATOM   13926 C C   . SER E 1 173 ? 76.616  -0.191  83.254  1.00 40.49  ? 173 SER E C   1 
ATOM   13927 O O   . SER E 1 173 ? 75.972  0.005   84.296  1.00 39.35  ? 173 SER E O   1 
ATOM   13928 C CB  . SER E 1 173 ? 78.089  1.453   82.144  1.00 36.00  ? 173 SER E CB  1 
ATOM   13929 O OG  . SER E 1 173 ? 79.387  1.955   81.912  1.00 49.55  ? 173 SER E OG  1 
ATOM   13930 N N   . ALA E 1 174 ? 76.087  -0.787  82.179  1.00 33.89  ? 174 ALA E N   1 
ATOM   13931 C CA  . ALA E 1 174 ? 74.657  -1.053  82.083  1.00 35.81  ? 174 ALA E CA  1 
ATOM   13932 C C   . ALA E 1 174 ? 74.206  -2.056  83.131  1.00 33.96  ? 174 ALA E C   1 
ATOM   13933 O O   . ALA E 1 174 ? 73.151  -1.885  83.750  1.00 35.71  ? 174 ALA E O   1 
ATOM   13934 C CB  . ALA E 1 174 ? 74.323  -1.561  80.684  1.00 28.18  ? 174 ALA E CB  1 
ATOM   13935 N N   . ILE E 1 175 ? 74.995  -3.106  83.343  1.00 33.37  ? 175 ILE E N   1 
ATOM   13936 C CA  . ILE E 1 175 ? 74.579  -4.174  84.241  1.00 37.26  ? 175 ILE E CA  1 
ATOM   13937 C C   . ILE E 1 175 ? 74.571  -3.688  85.685  1.00 37.76  ? 175 ILE E C   1 
ATOM   13938 O O   . ILE E 1 175 ? 73.642  -3.983  86.446  1.00 34.86  ? 175 ILE E O   1 
ATOM   13939 C CB  . ILE E 1 175 ? 75.485  -5.398  84.033  1.00 34.24  ? 175 ILE E CB  1 
ATOM   13940 C CG1 . ILE E 1 175 ? 75.116  -6.069  82.719  1.00 33.75  ? 175 ILE E CG1 1 
ATOM   13941 C CG2 . ILE E 1 175 ? 75.337  -6.391  85.162  1.00 42.41  ? 175 ILE E CG2 1 
ATOM   13942 C CD1 . ILE E 1 175 ? 75.839  -7.333  82.483  1.00 33.96  ? 175 ILE E CD1 1 
ATOM   13943 N N   . GLN E 1 176 ? 75.586  -2.912  86.074  1.00 37.38  ? 176 GLN E N   1 
ATOM   13944 C CA  . GLN E 1 176 ? 75.580  -2.276  87.388  1.00 43.52  ? 176 GLN E CA  1 
ATOM   13945 C C   . GLN E 1 176 ? 74.319  -1.455  87.593  1.00 41.62  ? 176 GLN E C   1 
ATOM   13946 O O   . GLN E 1 176 ? 73.639  -1.587  88.616  1.00 45.55  ? 176 GLN E O   1 
ATOM   13947 C CB  . GLN E 1 176 ? 76.810  -1.384  87.559  1.00 45.50  ? 176 GLN E CB  1 
ATOM   13948 C CG  . GLN E 1 176 ? 77.167  -1.127  89.011  1.00 49.30  ? 176 GLN E CG  1 
ATOM   13949 C CD  . GLN E 1 176 ? 78.604  -0.672  89.191  1.00 59.29  ? 176 GLN E CD  1 
ATOM   13950 O OE1 . GLN E 1 176 ? 79.303  -0.364  88.215  1.00 56.25  ? 176 GLN E OE1 1 
ATOM   13951 N NE2 . GLN E 1 176 ? 79.058  -0.631  90.444  1.00 57.28  ? 176 GLN E NE2 1 
ATOM   13952 N N   . GLU E 1 177 ? 73.983  -0.610  86.615  1.00 39.87  ? 177 GLU E N   1 
ATOM   13953 C CA  . GLU E 1 177 ? 72.842  0.289   86.750  1.00 39.03  ? 177 GLU E CA  1 
ATOM   13954 C C   . GLU E 1 177 ? 71.508  -0.469  86.747  1.00 39.09  ? 177 GLU E C   1 
ATOM   13955 O O   . GLU E 1 177 ? 70.578  -0.102  87.471  1.00 36.20  ? 177 GLU E O   1 
ATOM   13956 C CB  . GLU E 1 177 ? 72.905  1.333   85.631  1.00 41.92  ? 177 GLU E CB  1 
ATOM   13957 C CG  . GLU E 1 177 ? 71.667  2.218   85.461  1.00 48.93  ? 177 GLU E CG  1 
ATOM   13958 C CD  . GLU E 1 177 ? 71.498  2.723   84.019  1.00 57.43  ? 177 GLU E CD  1 
ATOM   13959 O OE1 . GLU E 1 177 ? 72.425  2.513   83.188  1.00 53.63  ? 177 GLU E OE1 1 
ATOM   13960 O OE2 . GLU E 1 177 ? 70.421  3.297   83.712  1.00 52.07  ? 177 GLU E OE2 1 
ATOM   13961 N N   . LEU E 1 178 ? 71.399  -1.543  85.970  1.00 36.43  ? 178 LEU E N   1 
ATOM   13962 C CA  . LEU E 1 178 ? 70.094  -2.131  85.689  1.00 34.18  ? 178 LEU E CA  1 
ATOM   13963 C C   . LEU E 1 178 ? 69.699  -3.268  86.629  1.00 36.14  ? 178 LEU E C   1 
ATOM   13964 O O   . LEU E 1 178 ? 68.521  -3.647  86.646  1.00 30.40  ? 178 LEU E O   1 
ATOM   13965 C CB  . LEU E 1 178 ? 70.058  -2.641  84.244  1.00 31.48  ? 178 LEU E CB  1 
ATOM   13966 C CG  . LEU E 1 178 ? 70.132  -1.568  83.153  1.00 30.34  ? 178 LEU E CG  1 
ATOM   13967 C CD1 . LEU E 1 178 ? 70.536  -2.211  81.820  1.00 28.86  ? 178 LEU E CD1 1 
ATOM   13968 C CD2 . LEU E 1 178 ? 68.812  -0.836  83.023  1.00 31.03  ? 178 LEU E CD2 1 
ATOM   13969 N N   . ILE E 1 179 ? 70.633  -3.827  87.410  1.00 35.08  ? 179 ILE E N   1 
ATOM   13970 C CA  . ILE E 1 179 ? 70.314  -5.003  88.216  1.00 32.18  ? 179 ILE E CA  1 
ATOM   13971 C C   . ILE E 1 179 ? 69.811  -4.653  89.609  1.00 31.96  ? 179 ILE E C   1 
ATOM   13972 O O   . ILE E 1 179 ? 69.380  -5.551  90.347  1.00 29.57  ? 179 ILE E O   1 
ATOM   13973 C CB  . ILE E 1 179 ? 71.534  -5.942  88.307  1.00 40.38  ? 179 ILE E CB  1 
ATOM   13974 C CG1 . ILE E 1 179 ? 71.063  -7.384  88.493  1.00 35.43  ? 179 ILE E CG1 1 
ATOM   13975 C CG2 . ILE E 1 179 ? 72.469  -5.514  89.419  1.00 35.16  ? 179 ILE E CG2 1 
ATOM   13976 C CD1 . ILE E 1 179 ? 72.154  -8.403  88.389  1.00 39.85  ? 179 ILE E CD1 1 
ATOM   13977 N N   . ALA E 1 180 ? 69.811  -3.375  89.982  1.00 33.34  ? 180 ALA E N   1 
ATOM   13978 C CA  . ALA E 1 180 ? 69.354  -3.017  91.317  1.00 30.78  ? 180 ALA E CA  1 
ATOM   13979 C C   . ALA E 1 180 ? 67.858  -3.255  91.476  1.00 35.58  ? 180 ALA E C   1 
ATOM   13980 O O   . ALA E 1 180 ? 67.409  -3.711  92.533  1.00 36.17  ? 180 ALA E O   1 
ATOM   13981 C CB  . ALA E 1 180 ? 69.699  -1.559  91.613  1.00 28.28  ? 180 ALA E CB  1 
ATOM   13982 N N   . GLU E 1 181 ? 67.077  -2.972  90.429  1.00 34.71  ? 181 GLU E N   1 
ATOM   13983 C CA  . GLU E 1 181 ? 65.625  -2.848  90.570  1.00 35.72  ? 181 GLU E CA  1 
ATOM   13984 C C   . GLU E 1 181 ? 64.969  -4.174  90.957  1.00 35.94  ? 181 GLU E C   1 
ATOM   13985 O O   . GLU E 1 181 ? 64.269  -4.265  91.975  1.00 36.36  ? 181 GLU E O   1 
ATOM   13986 C CB  . GLU E 1 181 ? 65.036  -2.298  89.268  1.00 32.92  ? 181 GLU E CB  1 
ATOM   13987 C CG  . GLU E 1 181 ? 63.524  -2.435  89.091  1.00 34.42  ? 181 GLU E CG  1 
ATOM   13988 C CD  . GLU E 1 181 ? 62.686  -1.842  90.215  1.00 42.60  ? 181 GLU E CD  1 
ATOM   13989 O OE1 . GLU E 1 181 ? 63.201  -1.004  90.990  1.00 43.80  ? 181 GLU E OE1 1 
ATOM   13990 O OE2 . GLU E 1 181 ? 61.480  -2.193  90.292  1.00 50.65  ? 181 GLU E OE2 1 
ATOM   13991 N N   . THR E 1 182 ? 65.161  -5.209  90.146  1.00 30.81  ? 182 THR E N   1 
ATOM   13992 C CA  . THR E 1 182 ? 64.541  -6.498  90.408  1.00 32.31  ? 182 THR E CA  1 
ATOM   13993 C C   . THR E 1 182 ? 65.527  -7.549  90.881  1.00 29.98  ? 182 THR E C   1 
ATOM   13994 O O   . THR E 1 182 ? 65.102  -8.596  91.376  1.00 33.76  ? 182 THR E O   1 
ATOM   13995 C CB  . THR E 1 182 ? 63.838  -7.021  89.148  1.00 31.81  ? 182 THR E CB  1 
ATOM   13996 O OG1 . THR E 1 182 ? 64.831  -7.333  88.170  1.00 29.83  ? 182 THR E OG1 1 
ATOM   13997 C CG2 . THR E 1 182 ? 62.891  -5.975  88.577  1.00 32.19  ? 182 THR E CG2 1 
ATOM   13998 N N   . GLY E 1 183 ? 66.819  -7.299  90.754  1.00 31.34  ? 183 GLY E N   1 
ATOM   13999 C CA  . GLY E 1 183 ? 67.812  -8.323  90.994  1.00 36.30  ? 183 GLY E CA  1 
ATOM   14000 C C   . GLY E 1 183 ? 68.163  -9.148  89.780  1.00 35.39  ? 183 GLY E C   1 
ATOM   14001 O O   . GLY E 1 183 ? 68.919  -10.120 89.911  1.00 33.94  ? 183 GLY E O   1 
ATOM   14002 N N   . MET E 1 184 ? 67.660  -8.778  88.596  1.00 34.99  ? 184 MET E N   1 
ATOM   14003 C CA  . MET E 1 184 ? 67.799  -9.595  87.395  1.00 34.22  ? 184 MET E CA  1 
ATOM   14004 C C   . MET E 1 184 ? 67.949  -8.709  86.171  1.00 28.83  ? 184 MET E C   1 
ATOM   14005 O O   . MET E 1 184 ? 67.253  -7.703  86.020  1.00 28.58  ? 184 MET E O   1 
ATOM   14006 C CB  . MET E 1 184 ? 66.595  -10.516 87.200  1.00 34.11  ? 184 MET E CB  1 
ATOM   14007 C CG  . MET E 1 184 ? 66.318  -11.454 88.356  1.00 35.40  ? 184 MET E CG  1 
ATOM   14008 S SD  . MET E 1 184 ? 64.664  -12.162 88.252  1.00 41.21  ? 184 MET E SD  1 
ATOM   14009 C CE  . MET E 1 184 ? 63.634  -10.696 88.347  1.00 38.30  ? 184 MET E CE  1 
ATOM   14010 N N   . VAL E 1 185 ? 68.830  -9.127  85.280  1.00 31.79  ? 185 VAL E N   1 
ATOM   14011 C CA  . VAL E 1 185 ? 69.142  -8.408  84.060  1.00 26.02  ? 185 VAL E CA  1 
ATOM   14012 C C   . VAL E 1 185 ? 69.274  -9.440  82.949  1.00 36.49  ? 185 VAL E C   1 
ATOM   14013 O O   . VAL E 1 185 ? 69.747  -10.559 83.182  1.00 32.23  ? 185 VAL E O   1 
ATOM   14014 C CB  . VAL E 1 185 ? 70.421  -7.565  84.237  1.00 29.15  ? 185 VAL E CB  1 
ATOM   14015 C CG1 . VAL E 1 185 ? 71.116  -7.313  82.915  1.00 32.81  ? 185 VAL E CG1 1 
ATOM   14016 C CG2 . VAL E 1 185 ? 70.069  -6.251  84.875  1.00 30.42  ? 185 VAL E CG2 1 
ATOM   14017 N N   . ILE E 1 186 ? 68.816  -9.093  81.749  1.00 27.79  ? 186 ILE E N   1 
ATOM   14018 C CA  . ILE E 1 186 ? 68.897  -10.001 80.620  1.00 28.58  ? 186 ILE E CA  1 
ATOM   14019 C C   . ILE E 1 186 ? 69.682  -9.299  79.518  1.00 28.85  ? 186 ILE E C   1 
ATOM   14020 O O   . ILE E 1 186 ? 69.467  -8.111  79.254  1.00 31.25  ? 186 ILE E O   1 
ATOM   14021 C CB  . ILE E 1 186 ? 67.499  -10.474 80.165  1.00 29.60  ? 186 ILE E CB  1 
ATOM   14022 C CG1 . ILE E 1 186 ? 67.621  -11.527 79.060  1.00 28.53  ? 186 ILE E CG1 1 
ATOM   14023 C CG2 . ILE E 1 186 ? 66.599  -9.303  79.732  1.00 29.22  ? 186 ILE E CG2 1 
ATOM   14024 C CD1 . ILE E 1 186 ? 66.277  -12.103 78.628  1.00 32.85  ? 186 ILE E CD1 1 
ATOM   14025 N N   . ALA E 1 187 ? 70.661  -10.002 78.956  1.00 25.27  ? 187 ALA E N   1 
ATOM   14026 C CA  . ALA E 1 187 ? 71.489  -9.491  77.874  1.00 22.85  ? 187 ALA E CA  1 
ATOM   14027 C C   . ALA E 1 187 ? 71.151  -10.281 76.617  1.00 28.17  ? 187 ALA E C   1 
ATOM   14028 O O   . ALA E 1 187 ? 71.120  -11.515 76.640  1.00 27.01  ? 187 ALA E O   1 
ATOM   14029 C CB  . ALA E 1 187 ? 72.979  -9.603  78.216  1.00 19.95  ? 187 ALA E CB  1 
ATOM   14030 N N   . LYS E 1 188 ? 70.848  -9.583  75.535  1.00 27.23  ? 188 LYS E N   1 
ATOM   14031 C CA  . LYS E 1 188 ? 70.349  -10.262 74.356  1.00 27.80  ? 188 LYS E CA  1 
ATOM   14032 C C   . LYS E 1 188 ? 71.200  -9.932  73.150  1.00 27.87  ? 188 LYS E C   1 
ATOM   14033 O O   . LYS E 1 188 ? 71.554  -8.773  72.916  1.00 29.49  ? 188 LYS E O   1 
ATOM   14034 C CB  . LYS E 1 188 ? 68.899  -9.904  74.058  1.00 22.33  ? 188 LYS E CB  1 
ATOM   14035 C CG  . LYS E 1 188 ? 68.002  -9.833  75.258  1.00 28.36  ? 188 LYS E CG  1 
ATOM   14036 C CD  . LYS E 1 188 ? 66.694  -9.113  74.896  1.00 29.03  ? 188 LYS E CD  1 
ATOM   14037 C CE  . LYS E 1 188 ? 65.552  -9.457  75.851  1.00 35.85  ? 188 LYS E CE  1 
ATOM   14038 N NZ  . LYS E 1 188 ? 64.203  -9.322  75.176  1.00 39.01  ? 188 LYS E NZ  1 
ATOM   14039 N N   . GLN E 1 189 ? 71.491  -10.971 72.387  1.00 24.92  ? 189 GLN E N   1 
ATOM   14040 C CA  . GLN E 1 189 ? 72.036  -10.823 71.050  1.00 29.47  ? 189 GLN E CA  1 
ATOM   14041 C C   . GLN E 1 189 ? 71.108  -9.965  70.199  1.00 26.50  ? 189 GLN E C   1 
ATOM   14042 O O   . GLN E 1 189 ? 69.883  -10.029 70.327  1.00 29.33  ? 189 GLN E O   1 
ATOM   14043 C CB  . GLN E 1 189 ? 72.211  -12.213 70.456  1.00 31.05  ? 189 GLN E CB  1 
ATOM   14044 C CG  . GLN E 1 189 ? 72.947  -12.283 69.167  1.00 40.83  ? 189 GLN E CG  1 
ATOM   14045 C CD  . GLN E 1 189 ? 73.008  -13.701 68.692  1.00 43.01  ? 189 GLN E CD  1 
ATOM   14046 O OE1 . GLN E 1 189 ? 71.980  -14.377 68.606  1.00 48.04  ? 189 GLN E OE1 1 
ATOM   14047 N NE2 . GLN E 1 189 ? 74.214  -14.180 68.407  1.00 45.58  ? 189 GLN E NE2 1 
ATOM   14048 N N   . ASP E 1 190 ? 71.688  -9.129  69.345  1.00 28.25  ? 190 ASP E N   1 
ATOM   14049 C CA  . ASP E 1 190 ? 70.865  -8.123  68.678  1.00 31.05  ? 190 ASP E CA  1 
ATOM   14050 C C   . ASP E 1 190 ? 69.956  -8.729  67.619  1.00 31.37  ? 190 ASP E C   1 
ATOM   14051 O O   . ASP E 1 190 ? 68.843  -8.231  67.412  1.00 32.95  ? 190 ASP E O   1 
ATOM   14052 C CB  . ASP E 1 190 ? 71.744  -7.044  68.056  1.00 30.03  ? 190 ASP E CB  1 
ATOM   14053 C CG  . ASP E 1 190 ? 70.994  -5.751  67.832  1.00 27.08  ? 190 ASP E CG  1 
ATOM   14054 O OD1 . ASP E 1 190 ? 69.984  -5.497  68.525  1.00 29.87  ? 190 ASP E OD1 1 
ATOM   14055 O OD2 . ASP E 1 190 ? 71.409  -4.987  66.951  1.00 30.81  ? 190 ASP E OD2 1 
ATOM   14056 N N   . ARG E 1 191 ? 70.398  -9.785  66.938  1.00 30.99  ? 191 ARG E N   1 
ATOM   14057 C CA  . ARG E 1 191 ? 69.610  -10.414 65.891  1.00 39.73  ? 191 ARG E CA  1 
ATOM   14058 C C   . ARG E 1 191 ? 69.152  -11.810 66.305  1.00 46.59  ? 191 ARG E C   1 
ATOM   14059 O O   . ARG E 1 191 ? 69.479  -12.310 67.386  1.00 52.23  ? 191 ARG E O   1 
ATOM   14060 C CB  . ARG E 1 191 ? 70.397  -10.463 64.582  1.00 37.54  ? 191 ARG E CB  1 
ATOM   14061 C CG  . ARG E 1 191 ? 70.476  -9.112  63.925  1.00 41.43  ? 191 ARG E CG  1 
ATOM   14062 C CD  . ARG E 1 191 ? 71.008  -9.168  62.506  1.00 48.63  ? 191 ARG E CD  1 
ATOM   14063 N NE  . ARG E 1 191 ? 71.642  -7.904  62.150  1.00 46.49  ? 191 ARG E NE  1 
ATOM   14064 C CZ  . ARG E 1 191 ? 71.983  -7.552  60.920  1.00 49.63  ? 191 ARG E CZ  1 
ATOM   14065 N NH1 . ARG E 1 191 ? 71.754  -8.350  59.881  1.00 53.26  ? 191 ARG E NH1 1 
ATOM   14066 N NH2 . ARG E 1 191 ? 72.561  -6.369  60.725  1.00 45.49  ? 191 ARG E NH2 1 
ATOM   14067 N N   . SER E 1 192 ? 68.381  -12.426 65.403  1.00 56.14  ? 192 SER E N   1 
ATOM   14068 C CA  . SER E 1 192 ? 67.756  -13.740 65.548  1.00 56.89  ? 192 SER E CA  1 
ATOM   14069 C C   . SER E 1 192 ? 66.589  -13.694 66.528  1.00 59.78  ? 192 SER E C   1 
ATOM   14070 O O   . SER E 1 192 ? 65.446  -13.454 66.123  1.00 59.81  ? 192 SER E O   1 
ATOM   14071 C CB  . SER E 1 192 ? 68.774  -14.809 65.985  1.00 55.18  ? 192 SER E CB  1 
ATOM   14072 O OG  . SER E 1 192 ? 69.292  -15.525 64.876  1.00 63.70  ? 192 SER E OG  1 
ATOM   14073 N N   . GLY E 1 193 ? 66.873  -13.889 67.819  1.00 58.27  ? 193 GLY E N   1 
ATOM   14074 C CA  . GLY E 1 193 ? 65.862  -14.226 68.796  1.00 55.52  ? 193 GLY E CA  1 
ATOM   14075 C C   . GLY E 1 193 ? 65.712  -15.714 69.036  1.00 64.78  ? 193 GLY E C   1 
ATOM   14076 O O   . GLY E 1 193 ? 65.038  -16.109 70.000  1.00 61.97  ? 193 GLY E O   1 
ATOM   14077 N N   . GLY E 1 194 ? 66.324  -16.547 68.186  1.00 65.14  ? 194 GLY E N   1 
ATOM   14078 C CA  . GLY E 1 194 ? 66.278  -17.985 68.331  1.00 67.46  ? 194 GLY E CA  1 
ATOM   14079 C C   . GLY E 1 194 ? 67.563  -18.546 68.932  1.00 68.66  ? 194 GLY E C   1 
ATOM   14080 O O   . GLY E 1 194 ? 68.498  -17.820 69.266  1.00 69.92  ? 194 GLY E O   1 
ATOM   14081 N N   . GLY E 1 195 ? 67.588  -19.873 69.053  1.00 72.88  ? 195 GLY E N   1 
ATOM   14082 C CA  . GLY E 1 195 ? 68.693  -20.547 69.736  1.00 72.84  ? 195 GLY E CA  1 
ATOM   14083 C C   . GLY E 1 195 ? 68.971  -19.984 71.113  1.00 74.08  ? 195 GLY E C   1 
ATOM   14084 O O   . GLY E 1 195 ? 70.137  -19.855 71.520  1.00 71.58  ? 195 GLY E O   1 
ATOM   14085 N N   . HIS E 1 196 ? 67.907  -19.654 71.851  1.00 74.03  ? 196 HIS E N   1 
ATOM   14086 C CA  . HIS E 1 196 ? 67.974  -18.795 73.026  1.00 65.30  ? 196 HIS E CA  1 
ATOM   14087 C C   . HIS E 1 196 ? 68.587  -17.455 72.618  1.00 65.87  ? 196 HIS E C   1 
ATOM   14088 O O   . HIS E 1 196 ? 67.849  -16.521 72.277  1.00 60.08  ? 196 HIS E O   1 
ATOM   14089 C CB  . HIS E 1 196 ? 68.748  -19.476 74.159  1.00 66.69  ? 196 HIS E CB  1 
ATOM   14090 C CG  . HIS E 1 196 ? 68.166  -20.798 74.580  1.00 74.19  ? 196 HIS E CG  1 
ATOM   14091 N ND1 . HIS E 1 196 ? 68.945  -21.887 74.914  1.00 70.83  ? 196 HIS E ND1 1 
ATOM   14092 C CD2 . HIS E 1 196 ? 66.880  -21.206 74.708  1.00 71.03  ? 196 HIS E CD2 1 
ATOM   14093 C CE1 . HIS E 1 196 ? 68.165  -22.904 75.239  1.00 70.50  ? 196 HIS E CE1 1 
ATOM   14094 N NE2 . HIS E 1 196 ? 66.908  -22.517 75.122  1.00 71.08  ? 196 HIS E NE2 1 
ATOM   14095 N N   . GLY E 1 197 ? 69.921  -17.352 72.613  1.00 63.39  ? 197 GLY E N   1 
ATOM   14096 C CA  . GLY E 1 197 ? 70.568  -16.113 72.219  1.00 53.54  ? 197 GLY E CA  1 
ATOM   14097 C C   . GLY E 1 197 ? 70.548  -15.016 73.259  1.00 45.38  ? 197 GLY E C   1 
ATOM   14098 O O   . GLY E 1 197 ? 70.908  -13.876 72.940  1.00 35.27  ? 197 GLY E O   1 
ATOM   14099 N N   . ASN E 1 198 ? 70.112  -15.317 74.484  1.00 42.53  ? 198 ASN E N   1 
ATOM   14100 C CA  . ASN E 1 198 ? 70.090  -14.365 75.584  1.00 39.06  ? 198 ASN E CA  1 
ATOM   14101 C C   . ASN E 1 198 ? 70.713  -15.012 76.814  1.00 42.93  ? 198 ASN E C   1 
ATOM   14102 O O   . ASN E 1 198 ? 70.645  -16.233 76.992  1.00 46.34  ? 198 ASN E O   1 
ATOM   14103 C CB  . ASN E 1 198 ? 68.664  -13.905 75.929  1.00 37.65  ? 198 ASN E CB  1 
ATOM   14104 C CG  . ASN E 1 198 ? 67.795  -13.642 74.695  1.00 41.22  ? 198 ASN E CG  1 
ATOM   14105 O OD1 . ASN E 1 198 ? 68.280  -13.240 73.637  1.00 33.66  ? 198 ASN E OD1 1 
ATOM   14106 N ND2 . ASN E 1 198 ? 66.486  -13.846 74.851  1.00 38.04  ? 198 ASN E ND2 1 
ATOM   14107 N N   . ILE E 1 199 ? 71.316  -14.190 77.670  1.00 34.62  ? 199 ILE E N   1 
ATOM   14108 C CA  . ILE E 1 199 ? 71.896  -14.666 78.923  1.00 37.94  ? 199 ILE E CA  1 
ATOM   14109 C C   . ILE E 1 199 ? 71.322  -13.857 80.076  1.00 38.02  ? 199 ILE E C   1 
ATOM   14110 O O   . ILE E 1 199 ? 71.281  -12.622 80.014  1.00 38.78  ? 199 ILE E O   1 
ATOM   14111 C CB  . ILE E 1 199 ? 73.432  -14.576 78.919  1.00 43.03  ? 199 ILE E CB  1 
ATOM   14112 C CG1 . ILE E 1 199 ? 74.020  -15.604 77.952  1.00 42.02  ? 199 ILE E CG1 1 
ATOM   14113 C CG2 . ILE E 1 199 ? 73.980  -14.761 80.337  1.00 38.23  ? 199 ILE E CG2 1 
ATOM   14114 C CD1 . ILE E 1 199 ? 75.376  -15.230 77.433  1.00 43.03  ? 199 ILE E CD1 1 
ATOM   14115 N N   . GLY E 1 200 ? 70.872  -14.558 81.137  1.00 38.20  ? 200 GLY E N   1 
ATOM   14116 C CA  . GLY E 1 200 ? 70.435  -13.885 82.342  1.00 36.51  ? 200 GLY E CA  1 
ATOM   14117 C C   . GLY E 1 200 ? 71.580  -13.570 83.303  1.00 37.50  ? 200 GLY E C   1 
ATOM   14118 O O   . GLY E 1 200 ? 72.639  -14.195 83.288  1.00 37.79  ? 200 GLY E O   1 
ATOM   14119 N N   . ILE E 1 201 ? 71.351  -12.563 84.140  1.00 36.47  ? 201 ILE E N   1 
ATOM   14120 C CA  . ILE E 1 201 ? 72.274  -12.164 85.196  1.00 34.58  ? 201 ILE E CA  1 
ATOM   14121 C C   . ILE E 1 201 ? 71.440  -11.920 86.444  1.00 37.18  ? 201 ILE E C   1 
ATOM   14122 O O   . ILE E 1 201 ? 70.439  -11.197 86.391  1.00 35.44  ? 201 ILE E O   1 
ATOM   14123 C CB  . ILE E 1 201 ? 73.078  -10.904 84.819  1.00 35.48  ? 201 ILE E CB  1 
ATOM   14124 C CG1 . ILE E 1 201 ? 73.993  -11.183 83.623  1.00 41.29  ? 201 ILE E CG1 1 
ATOM   14125 C CG2 . ILE E 1 201 ? 73.915  -10.427 85.990  1.00 39.84  ? 201 ILE E CG2 1 
ATOM   14126 C CD1 . ILE E 1 201 ? 73.580  -10.482 82.347  1.00 31.13  ? 201 ILE E CD1 1 
ATOM   14127 N N   . SER E 1 202 ? 71.833  -12.531 87.560  1.00 38.22  ? 202 SER E N   1 
ATOM   14128 C CA  . SER E 1 202 ? 70.988  -12.552 88.744  1.00 38.39  ? 202 SER E CA  1 
ATOM   14129 C C   . SER E 1 202 ? 71.800  -12.297 90.009  1.00 39.19  ? 202 SER E C   1 
ATOM   14130 O O   . SER E 1 202 ? 72.977  -12.657 90.108  1.00 38.88  ? 202 SER E O   1 
ATOM   14131 C CB  . SER E 1 202 ? 70.253  -13.891 88.864  1.00 44.14  ? 202 SER E CB  1 
ATOM   14132 O OG  . SER E 1 202 ? 69.298  -13.847 89.907  1.00 46.49  ? 202 SER E OG  1 
ATOM   14133 N N   . THR E 1 203 ? 71.147  -11.675 90.987  1.00 43.46  ? 203 THR E N   1 
ATOM   14134 C CA  . THR E 1 203 ? 71.750  -11.486 92.297  1.00 47.13  ? 203 THR E CA  1 
ATOM   14135 C C   . THR E 1 203 ? 71.398  -12.596 93.278  1.00 44.49  ? 203 THR E C   1 
ATOM   14136 O O   . THR E 1 203 ? 71.991  -12.650 94.359  1.00 45.59  ? 203 THR E O   1 
ATOM   14137 C CB  . THR E 1 203 ? 71.335  -10.133 92.898  1.00 38.68  ? 203 THR E CB  1 
ATOM   14138 O OG1 . THR E 1 203 ? 69.924  -10.115 93.095  1.00 41.11  ? 203 THR E OG1 1 
ATOM   14139 C CG2 . THR E 1 203 ? 71.714  -8.993  91.986  1.00 32.48  ? 203 THR E CG2 1 
ATOM   14140 N N   . SER E 1 204 ? 70.431  -13.478 92.937  1.00 48.17  ? 204 SER E N   1 
ATOM   14141 C CA  . SER E 1 204 ? 70.046  -14.609 93.785  1.00 50.93  ? 204 SER E CA  1 
ATOM   14142 C C   . SER E 1 204 ? 70.717  -15.879 93.295  1.00 55.59  ? 204 SER E C   1 
ATOM   14143 O O   . SER E 1 204 ? 70.704  -16.141 92.085  1.00 57.21  ? 204 SER E O   1 
ATOM   14144 C CB  . SER E 1 204 ? 68.532  -14.806 93.786  1.00 47.34  ? 204 SER E CB  1 
ATOM   14145 O OG  . SER E 1 204 ? 67.857  -13.609 94.121  1.00 45.17  ? 204 SER E OG  1 
ATOM   14146 N N   . PRO E 1 205 ? 71.298  -16.697 94.183  1.00 60.92  ? 205 PRO E N   1 
ATOM   14147 C CA  . PRO E 1 205 ? 71.944  -17.936 93.711  1.00 59.96  ? 205 PRO E CA  1 
ATOM   14148 C C   . PRO E 1 205 ? 70.973  -18.874 93.014  1.00 66.55  ? 205 PRO E C   1 
ATOM   14149 O O   . PRO E 1 205 ? 71.338  -19.512 92.017  1.00 73.84  ? 205 PRO E O   1 
ATOM   14150 C CB  . PRO E 1 205 ? 72.526  -18.548 94.997  1.00 58.67  ? 205 PRO E CB  1 
ATOM   14151 C CG  . PRO E 1 205 ? 72.572  -17.424 95.991  1.00 53.78  ? 205 PRO E CG  1 
ATOM   14152 C CD  . PRO E 1 205 ? 71.411  -16.531 95.642  1.00 54.57  ? 205 PRO E CD  1 
ATOM   14153 N N   . GLU E 1 206 ? 69.746  -18.981 93.518  1.00 66.57  ? 206 GLU E N   1 
ATOM   14154 C CA  . GLU E 1 206 ? 68.656  -19.535 92.725  1.00 72.93  ? 206 GLU E CA  1 
ATOM   14155 C C   . GLU E 1 206 ? 68.461  -18.665 91.490  1.00 74.92  ? 206 GLU E C   1 
ATOM   14156 O O   . GLU E 1 206 ? 68.199  -17.462 91.606  1.00 72.30  ? 206 GLU E O   1 
ATOM   14157 C CB  . GLU E 1 206 ? 67.375  -19.588 93.562  1.00 71.66  ? 206 GLU E CB  1 
ATOM   14158 C CG  . GLU E 1 206 ? 66.163  -20.223 92.879  1.00 77.36  ? 206 GLU E CG  1 
ATOM   14159 C CD  . GLU E 1 206 ? 65.342  -19.241 92.048  1.00 78.90  ? 206 GLU E CD  1 
ATOM   14160 O OE1 . GLU E 1 206 ? 65.212  -18.070 92.466  1.00 75.26  ? 206 GLU E OE1 1 
ATOM   14161 O OE2 . GLU E 1 206 ? 64.807  -19.647 90.989  1.00 80.25  ? 206 GLU E OE2 1 
ATOM   14162 N N   . SER E 1 207 ? 68.611  -19.256 90.303  1.00 73.80  ? 207 SER E N   1 
ATOM   14163 C CA  . SER E 1 207 ? 68.647  -18.442 89.086  1.00 72.89  ? 207 SER E CA  1 
ATOM   14164 C C   . SER E 1 207 ? 68.081  -19.248 87.917  1.00 71.89  ? 207 SER E C   1 
ATOM   14165 O O   . SER E 1 207 ? 68.779  -20.099 87.356  1.00 76.78  ? 207 SER E O   1 
ATOM   14166 C CB  . SER E 1 207 ? 70.071  -17.973 88.792  1.00 73.92  ? 207 SER E CB  1 
ATOM   14167 O OG  . SER E 1 207 ? 70.895  -17.891 89.949  1.00 66.10  ? 207 SER E OG  1 
ATOM   14168 N N   . SER E 1 208 ? 66.839  -18.958 87.531  1.00 68.83  ? 208 SER E N   1 
ATOM   14169 C CA  . SER E 1 208 ? 66.317  -19.497 86.275  1.00 73.83  ? 208 SER E CA  1 
ATOM   14170 C C   . SER E 1 208 ? 65.156  -18.638 85.799  1.00 71.33  ? 208 SER E C   1 
ATOM   14171 O O   . SER E 1 208 ? 64.154  -18.495 86.510  1.00 71.14  ? 208 SER E O   1 
ATOM   14172 C CB  . SER E 1 208 ? 65.884  -20.953 86.423  1.00 70.54  ? 208 SER E CB  1 
ATOM   14173 O OG  . SER E 1 208 ? 65.878  -21.580 85.151  1.00 72.46  ? 208 SER E OG  1 
ATOM   14174 N N   . PHE E 1 209 ? 65.294  -18.078 84.597  1.00 64.96  ? 209 PHE E N   1 
ATOM   14175 C CA  . PHE E 1 209 ? 64.310  -17.176 84.008  1.00 60.77  ? 209 PHE E CA  1 
ATOM   14176 C C   . PHE E 1 209 ? 64.019  -17.623 82.580  1.00 60.75  ? 209 PHE E C   1 
ATOM   14177 O O   . PHE E 1 209 ? 64.959  -17.737 81.768  1.00 56.53  ? 209 PHE E O   1 
ATOM   14178 C CB  . PHE E 1 209 ? 64.822  -15.734 84.027  1.00 66.14  ? 209 PHE E CB  1 
ATOM   14179 C CG  . PHE E 1 209 ? 65.694  -15.410 85.208  1.00 73.72  ? 209 PHE E CG  1 
ATOM   14180 C CD1 . PHE E 1 209 ? 65.236  -15.620 86.505  1.00 80.25  ? 209 PHE E CD1 1 
ATOM   14181 C CD2 . PHE E 1 209 ? 66.947  -14.854 85.030  1.00 74.79  ? 209 PHE E CD2 1 
ATOM   14182 C CE1 . PHE E 1 209 ? 66.025  -15.329 87.603  1.00 80.25  ? 209 PHE E CE1 1 
ATOM   14183 C CE2 . PHE E 1 209 ? 67.734  -14.543 86.123  1.00 78.78  ? 209 PHE E CE2 1 
ATOM   14184 C CZ  . PHE E 1 209 ? 67.274  -14.786 87.412  1.00 82.21  ? 209 PHE E CZ  1 
ATOM   14185 N N   . PRO E 1 210 ? 62.759  -17.858 82.214  1.00 57.94  ? 210 PRO E N   1 
ATOM   14186 C CA  . PRO E 1 210 ? 62.472  -18.412 80.886  1.00 55.42  ? 210 PRO E CA  1 
ATOM   14187 C C   . PRO E 1 210 ? 62.851  -17.446 79.775  1.00 55.40  ? 210 PRO E C   1 
ATOM   14188 O O   . PRO E 1 210 ? 62.811  -16.224 79.940  1.00 54.21  ? 210 PRO E O   1 
ATOM   14189 C CB  . PRO E 1 210 ? 60.958  -18.642 80.925  1.00 58.59  ? 210 PRO E CB  1 
ATOM   14190 C CG  . PRO E 1 210 ? 60.466  -17.584 81.852  1.00 53.51  ? 210 PRO E CG  1 
ATOM   14191 C CD  . PRO E 1 210 ? 61.522  -17.501 82.933  1.00 52.70  ? 210 PRO E CD  1 
ATOM   14192 N N   . GLY E 1 211 ? 63.228  -18.014 78.631  1.00 53.06  ? 211 GLY E N   1 
ATOM   14193 C CA  . GLY E 1 211 ? 63.680  -17.223 77.499  1.00 58.75  ? 211 GLY E CA  1 
ATOM   14194 C C   . GLY E 1 211 ? 65.166  -16.934 77.459  1.00 52.49  ? 211 GLY E C   1 
ATOM   14195 O O   . GLY E 1 211 ? 65.585  -15.988 76.775  1.00 42.92  ? 211 GLY E O   1 
ATOM   14196 N N   . THR E 1 212 ? 65.976  -17.698 78.190  1.00 53.77  ? 212 THR E N   1 
ATOM   14197 C CA  . THR E 1 212 ? 67.415  -17.492 78.266  1.00 46.36  ? 212 THR E CA  1 
ATOM   14198 C C   . THR E 1 212 ? 68.103  -18.846 78.339  1.00 50.51  ? 212 THR E C   1 
ATOM   14199 O O   . THR E 1 212 ? 67.547  -19.809 78.870  1.00 54.10  ? 212 THR E O   1 
ATOM   14200 C CB  . THR E 1 212 ? 67.826  -16.658 79.489  1.00 45.92  ? 212 THR E CB  1 
ATOM   14201 O OG1 . THR E 1 212 ? 67.824  -17.486 80.653  1.00 47.96  ? 212 THR E OG1 1 
ATOM   14202 C CG2 . THR E 1 212 ? 66.888  -15.488 79.718  1.00 47.81  ? 212 THR E CG2 1 
ATOM   14203 N N   . ARG E 1 213 ? 69.328  -18.912 77.811  1.00 52.86  ? 213 ARG E N   1 
ATOM   14204 C CA  . ARG E 1 213 ? 70.049  -20.180 77.815  1.00 51.98  ? 213 ARG E CA  1 
ATOM   14205 C C   . ARG E 1 213 ? 70.738  -20.438 79.145  1.00 51.14  ? 213 ARG E C   1 
ATOM   14206 O O   . ARG E 1 213 ? 70.839  -21.596 79.567  1.00 56.81  ? 213 ARG E O   1 
ATOM   14207 C CB  . ARG E 1 213 ? 71.057  -20.227 76.666  1.00 52.55  ? 213 ARG E CB  1 
ATOM   14208 C CG  . ARG E 1 213 ? 72.301  -19.389 76.824  1.00 50.03  ? 213 ARG E CG  1 
ATOM   14209 C CD  . ARG E 1 213 ? 72.881  -19.078 75.453  1.00 55.08  ? 213 ARG E CD  1 
ATOM   14210 N NE  . ARG E 1 213 ? 74.340  -19.097 75.447  1.00 54.30  ? 213 ARG E NE  1 
ATOM   14211 C CZ  . ARG E 1 213 ? 75.092  -18.385 74.619  1.00 51.53  ? 213 ARG E CZ  1 
ATOM   14212 N NH1 . ARG E 1 213 ? 74.557  -17.562 73.731  1.00 51.48  ? 213 ARG E NH1 1 
ATOM   14213 N NH2 . ARG E 1 213 ? 76.415  -18.501 74.685  1.00 54.11  ? 213 ARG E NH2 1 
ATOM   14214 N N   . GLU E 1 214 ? 71.186  -19.391 79.828  1.00 49.48  ? 214 GLU E N   1 
ATOM   14215 C CA  . GLU E 1 214 ? 71.841  -19.554 81.118  1.00 52.29  ? 214 GLU E CA  1 
ATOM   14216 C C   . GLU E 1 214 ? 71.755  -18.246 81.891  1.00 49.52  ? 214 GLU E C   1 
ATOM   14217 O O   . GLU E 1 214 ? 71.400  -17.195 81.347  1.00 43.47  ? 214 GLU E O   1 
ATOM   14218 C CB  . GLU E 1 214 ? 73.297  -19.983 80.957  1.00 46.49  ? 214 GLU E CB  1 
ATOM   14219 C CG  . GLU E 1 214 ? 74.123  -18.947 80.270  1.00 49.74  ? 214 GLU E CG  1 
ATOM   14220 C CD  . GLU E 1 214 ? 75.581  -19.250 80.357  1.00 52.56  ? 214 GLU E CD  1 
ATOM   14221 O OE1 . GLU E 1 214 ? 76.013  -19.752 81.419  1.00 57.10  ? 214 GLU E OE1 1 
ATOM   14222 O OE2 . GLU E 1 214 ? 76.290  -18.992 79.365  1.00 49.37  ? 214 GLU E OE2 1 
ATOM   14223 N N   . VAL E 1 215 ? 72.089  -18.331 83.179  1.00 49.66  ? 215 VAL E N   1 
ATOM   14224 C CA  . VAL E 1 215 ? 71.989  -17.198 84.092  1.00 45.79  ? 215 VAL E CA  1 
ATOM   14225 C C   . VAL E 1 215 ? 73.260  -17.064 84.926  1.00 48.35  ? 215 VAL E C   1 
ATOM   14226 O O   . VAL E 1 215 ? 73.414  -17.717 85.965  1.00 53.01  ? 215 VAL E O   1 
ATOM   14227 C CB  . VAL E 1 215 ? 70.763  -17.335 85.009  1.00 47.77  ? 215 VAL E CB  1 
ATOM   14228 C CG1 . VAL E 1 215 ? 70.678  -16.131 85.919  1.00 47.29  ? 215 VAL E CG1 1 
ATOM   14229 C CG2 . VAL E 1 215 ? 69.479  -17.520 84.192  1.00 51.69  ? 215 VAL E CG2 1 
ATOM   14230 N N   . LEU E 1 216 ? 74.172  -16.203 84.492  1.00 47.12  ? 216 LEU E N   1 
ATOM   14231 C CA  . LEU E 1 216 ? 75.370  -15.940 85.266  1.00 41.41  ? 216 LEU E CA  1 
ATOM   14232 C C   . LEU E 1 216 ? 75.013  -15.265 86.586  1.00 43.82  ? 216 LEU E C   1 
ATOM   14233 O O   . LEU E 1 216 ? 73.924  -14.715 86.760  1.00 42.52  ? 216 LEU E O   1 
ATOM   14234 C CB  . LEU E 1 216 ? 76.322  -15.056 84.467  1.00 39.23  ? 216 LEU E CB  1 
ATOM   14235 C CG  . LEU E 1 216 ? 76.808  -15.715 83.182  1.00 45.06  ? 216 LEU E CG  1 
ATOM   14236 C CD1 . LEU E 1 216 ? 77.184  -14.651 82.166  1.00 43.68  ? 216 LEU E CD1 1 
ATOM   14237 C CD2 . LEU E 1 216 ? 77.976  -16.649 83.474  1.00 39.73  ? 216 LEU E CD2 1 
ATOM   14238 N N   . ALA E 1 217 ? 75.956  -15.296 87.522  1.00 42.67  ? 217 ALA E N   1 
ATOM   14239 C CA  . ALA E 1 217 ? 75.794  -14.641 88.812  1.00 42.76  ? 217 ALA E CA  1 
ATOM   14240 C C   . ALA E 1 217 ? 76.381  -13.238 88.741  1.00 42.87  ? 217 ALA E C   1 
ATOM   14241 O O   . ALA E 1 217 ? 77.471  -13.043 88.198  1.00 38.86  ? 217 ALA E O   1 
ATOM   14242 C CB  . ALA E 1 217 ? 76.469  -15.442 89.924  1.00 43.84  ? 217 ALA E CB  1 
ATOM   14243 N N   . TYR E 1 218 ? 75.655  -12.262 89.273  1.00 43.60  ? 218 TYR E N   1 
ATOM   14244 C CA  . TYR E 1 218 ? 76.210  -10.923 89.340  1.00 38.44  ? 218 TYR E CA  1 
ATOM   14245 C C   . TYR E 1 218 ? 77.300  -10.865 90.408  1.00 45.49  ? 218 TYR E C   1 
ATOM   14246 O O   . TYR E 1 218 ? 77.239  -11.556 91.426  1.00 43.42  ? 218 TYR E O   1 
ATOM   14247 C CB  . TYR E 1 218 ? 75.116  -9.910  89.629  1.00 35.07  ? 218 TYR E CB  1 
ATOM   14248 C CG  . TYR E 1 218 ? 75.627  -8.493  89.664  1.00 41.85  ? 218 TYR E CG  1 
ATOM   14249 C CD1 . TYR E 1 218 ? 75.778  -7.752  88.490  1.00 37.53  ? 218 TYR E CD1 1 
ATOM   14250 C CD2 . TYR E 1 218 ? 75.971  -7.895  90.870  1.00 40.36  ? 218 TYR E CD2 1 
ATOM   14251 C CE1 . TYR E 1 218 ? 76.253  -6.453  88.528  1.00 38.29  ? 218 TYR E CE1 1 
ATOM   14252 C CE2 . TYR E 1 218 ? 76.443  -6.602  90.915  1.00 42.71  ? 218 TYR E CE2 1 
ATOM   14253 C CZ  . TYR E 1 218 ? 76.584  -5.886  89.749  1.00 42.99  ? 218 TYR E CZ  1 
ATOM   14254 O OH  . TYR E 1 218 ? 77.060  -4.599  89.822  1.00 48.34  ? 218 TYR E OH  1 
ATOM   14255 N N   . ALA E 1 219 ? 78.314  -10.035 90.160  1.00 48.45  ? 219 ALA E N   1 
ATOM   14256 C CA  . ALA E 1 219 ? 79.486  -9.976  91.030  1.00 44.63  ? 219 ALA E CA  1 
ATOM   14257 C C   . ALA E 1 219 ? 80.084  -8.578  90.947  1.00 50.34  ? 219 ALA E C   1 
ATOM   14258 O O   . ALA E 1 219 ? 80.697  -8.219  89.933  1.00 46.91  ? 219 ALA E O   1 
ATOM   14259 C CB  . ALA E 1 219 ? 80.504  -11.038 90.633  1.00 46.14  ? 219 ALA E CB  1 
ATOM   14260 N N   . ASN E 1 220 ? 79.912  -7.795  92.018  1.00 45.99  ? 220 ASN E N   1 
ATOM   14261 C CA  . ASN E 1 220 ? 80.392  -6.416  92.033  1.00 50.77  ? 220 ASN E CA  1 
ATOM   14262 C C   . ASN E 1 220 ? 81.902  -6.311  91.851  1.00 58.04  ? 220 ASN E C   1 
ATOM   14263 O O   . ASN E 1 220 ? 82.396  -5.238  91.481  1.00 56.91  ? 220 ASN E O   1 
ATOM   14264 C CB  . ASN E 1 220 ? 79.994  -5.740  93.347  1.00 50.44  ? 220 ASN E CB  1 
ATOM   14265 C CG  . ASN E 1 220 ? 79.789  -4.246  93.197  1.00 52.93  ? 220 ASN E CG  1 
ATOM   14266 O OD1 . ASN E 1 220 ? 78.688  -3.781  92.873  1.00 53.39  ? 220 ASN E OD1 1 
ATOM   14267 N ND2 . ASN E 1 220 ? 80.850  -3.478  93.443  1.00 52.14  ? 220 ASN E ND2 1 
ATOM   14268 N N   . ASP E 1 221 ? 82.642  -7.393  92.100  1.00 56.03  ? 221 ASP E N   1 
ATOM   14269 C CA  . ASP E 1 221 ? 84.097  -7.362  92.086  1.00 60.48  ? 221 ASP E CA  1 
ATOM   14270 C C   . ASP E 1 221 ? 84.693  -7.910  90.801  1.00 58.12  ? 221 ASP E C   1 
ATOM   14271 O O   . ASP E 1 221 ? 85.880  -7.684  90.545  1.00 60.56  ? 221 ASP E O   1 
ATOM   14272 C CB  . ASP E 1 221 ? 84.648  -8.151  93.282  1.00 58.79  ? 221 ASP E CB  1 
ATOM   14273 C CG  . ASP E 1 221 ? 83.895  -9.445  93.510  1.00 58.95  ? 221 ASP E CG  1 
ATOM   14274 O OD1 . ASP E 1 221 ? 82.693  -9.487  93.159  1.00 53.96  ? 221 ASP E OD1 1 
ATOM   14275 O OD2 . ASP E 1 221 ? 84.490  -10.408 94.045  1.00 61.38  ? 221 ASP E OD2 1 
ATOM   14276 N N   . GLN E 1 222 ? 83.909  -8.616  89.993  1.00 57.26  ? 222 GLN E N   1 
ATOM   14277 C CA  . GLN E 1 222 ? 84.368  -9.145  88.716  1.00 59.96  ? 222 GLN E CA  1 
ATOM   14278 C C   . GLN E 1 222 ? 83.485  -8.633  87.579  1.00 58.18  ? 222 GLN E C   1 
ATOM   14279 O O   . GLN E 1 222 ? 83.095  -9.374  86.667  1.00 52.45  ? 222 GLN E O   1 
ATOM   14280 C CB  . GLN E 1 222 ? 84.426  -10.673 88.746  1.00 60.59  ? 222 GLN E CB  1 
ATOM   14281 C CG  . GLN E 1 222 ? 85.802  -11.260 89.149  1.00 68.12  ? 222 GLN E CG  1 
ATOM   14282 C CD  . GLN E 1 222 ? 86.927  -11.021 88.122  1.00 70.63  ? 222 GLN E CD  1 
ATOM   14283 O OE1 . GLN E 1 222 ? 86.802  -10.200 87.208  1.00 70.30  ? 222 GLN E OE1 1 
ATOM   14284 N NE2 . GLN E 1 222 ? 88.034  -11.744 88.285  1.00 69.18  ? 222 GLN E NE2 1 
ATOM   14285 N N   . LEU E 1 223 ? 83.173  -7.336  87.624  1.00 53.51  ? 223 LEU E N   1 
ATOM   14286 C CA  . LEU E 1 223 ? 82.376  -6.726  86.568  1.00 53.33  ? 223 LEU E CA  1 
ATOM   14287 C C   . LEU E 1 223 ? 83.070  -6.844  85.222  1.00 49.42  ? 223 LEU E C   1 
ATOM   14288 O O   . LEU E 1 223 ? 82.420  -7.096  84.201  1.00 44.11  ? 223 LEU E O   1 
ATOM   14289 C CB  . LEU E 1 223 ? 82.114  -5.258  86.897  1.00 54.96  ? 223 LEU E CB  1 
ATOM   14290 C CG  . LEU E 1 223 ? 80.895  -5.011  87.780  1.00 51.47  ? 223 LEU E CG  1 
ATOM   14291 C CD1 . LEU E 1 223 ? 80.874  -3.561  88.282  1.00 50.49  ? 223 LEU E CD1 1 
ATOM   14292 C CD2 . LEU E 1 223 ? 79.626  -5.368  87.022  1.00 47.02  ? 223 LEU E CD2 1 
ATOM   14293 N N   . ASP E 1 224 ? 84.397  -6.675  85.213  1.00 51.74  ? 224 ASP E N   1 
ATOM   14294 C CA  . ASP E 1 224 ? 85.179  -6.695  83.982  1.00 45.61  ? 224 ASP E CA  1 
ATOM   14295 C C   . ASP E 1 224 ? 85.045  -8.024  83.253  1.00 47.69  ? 224 ASP E C   1 
ATOM   14296 O O   . ASP E 1 224 ? 84.749  -8.058  82.052  1.00 44.95  ? 224 ASP E O   1 
ATOM   14297 C CB  . ASP E 1 224 ? 86.641  -6.420  84.311  1.00 49.74  ? 224 ASP E CB  1 
ATOM   14298 C CG  . ASP E 1 224 ? 86.938  -4.948  84.388  1.00 58.88  ? 224 ASP E CG  1 
ATOM   14299 O OD1 . ASP E 1 224 ? 85.988  -4.164  84.189  1.00 53.66  ? 224 ASP E OD1 1 
ATOM   14300 O OD2 . ASP E 1 224 ? 88.107  -4.576  84.644  1.00 63.49  ? 224 ASP E OD2 1 
ATOM   14301 N N   . THR E 1 225 ? 85.273  -9.130  83.968  1.00 48.37  ? 225 THR E N   1 
ATOM   14302 C CA  . THR E 1 225 ? 85.198  -10.459 83.365  1.00 45.81  ? 225 THR E CA  1 
ATOM   14303 C C   . THR E 1 225 ? 83.783  -10.803 82.916  1.00 45.63  ? 225 THR E C   1 
ATOM   14304 O O   . THR E 1 225 ? 83.606  -11.515 81.920  1.00 49.15  ? 225 THR E O   1 
ATOM   14305 C CB  . THR E 1 225 ? 85.729  -11.514 84.354  1.00 52.11  ? 225 THR E CB  1 
ATOM   14306 O OG1 . THR E 1 225 ? 86.136  -12.692 83.646  1.00 53.22  ? 225 THR E OG1 1 
ATOM   14307 C CG2 . THR E 1 225 ? 84.683  -11.899 85.388  1.00 45.95  ? 225 THR E CG2 1 
ATOM   14308 N N   . LEU E 1 226 ? 82.771  -10.296 83.617  1.00 44.76  ? 226 LEU E N   1 
ATOM   14309 C CA  . LEU E 1 226 ? 81.383  -10.637 83.329  1.00 45.00  ? 226 LEU E CA  1 
ATOM   14310 C C   . LEU E 1 226 ? 80.883  -9.903  82.093  1.00 39.38  ? 226 LEU E C   1 
ATOM   14311 O O   . LEU E 1 226 ? 80.270  -10.506 81.203  1.00 37.02  ? 226 LEU E O   1 
ATOM   14312 C CB  . LEU E 1 226 ? 80.519  -10.301 84.544  1.00 43.40  ? 226 LEU E CB  1 
ATOM   14313 C CG  . LEU E 1 226 ? 79.073  -10.738 84.504  1.00 41.32  ? 226 LEU E CG  1 
ATOM   14314 C CD1 . LEU E 1 226 ? 79.006  -12.181 84.082  1.00 41.82  ? 226 LEU E CD1 1 
ATOM   14315 C CD2 . LEU E 1 226 ? 78.478  -10.544 85.884  1.00 47.63  ? 226 LEU E CD2 1 
ATOM   14316 N N   . ALA E 1 227 ? 81.116  -8.593  82.042  1.00 41.45  ? 227 ALA E N   1 
ATOM   14317 C CA  . ALA E 1 227 ? 80.866  -7.846  80.818  1.00 38.29  ? 227 ALA E CA  1 
ATOM   14318 C C   . ALA E 1 227 ? 81.582  -8.492  79.641  1.00 39.50  ? 227 ALA E C   1 
ATOM   14319 O O   . ALA E 1 227 ? 81.005  -8.637  78.557  1.00 36.26  ? 227 ALA E O   1 
ATOM   14320 C CB  . ALA E 1 227 ? 81.311  -6.396  80.995  1.00 39.06  ? 227 ALA E CB  1 
ATOM   14321 N N   . ASP E 1 228 ? 82.826  -8.935  79.856  1.00 40.75  ? 228 ASP E N   1 
ATOM   14322 C CA  . ASP E 1 228 ? 83.590  -9.574  78.793  1.00 40.78  ? 228 ASP E CA  1 
ATOM   14323 C C   . ASP E 1 228 ? 82.894  -10.837 78.305  1.00 40.60  ? 228 ASP E C   1 
ATOM   14324 O O   . ASP E 1 228 ? 82.692  -11.019 77.102  1.00 40.10  ? 228 ASP E O   1 
ATOM   14325 C CB  . ASP E 1 228 ? 85.006  -9.893  79.282  1.00 45.49  ? 228 ASP E CB  1 
ATOM   14326 C CG  . ASP E 1 228 ? 85.989  -8.784  78.971  1.00 44.41  ? 228 ASP E CG  1 
ATOM   14327 O OD1 . ASP E 1 228 ? 85.653  -7.924  78.126  1.00 43.17  ? 228 ASP E OD1 1 
ATOM   14328 O OD2 . ASP E 1 228 ? 87.090  -8.766  79.568  1.00 49.90  ? 228 ASP E OD2 1 
ATOM   14329 N N   . THR E 1 229 ? 82.498  -11.714 79.233  1.00 40.60  ? 229 THR E N   1 
ATOM   14330 C CA  . THR E 1 229 ? 81.824  -12.950 78.840  1.00 37.73  ? 229 THR E CA  1 
ATOM   14331 C C   . THR E 1 229 ? 80.573  -12.664 78.017  1.00 37.42  ? 229 THR E C   1 
ATOM   14332 O O   . THR E 1 229 ? 80.253  -13.401 77.077  1.00 36.89  ? 229 THR E O   1 
ATOM   14333 C CB  . THR E 1 229 ? 81.455  -13.776 80.078  1.00 38.55  ? 229 THR E CB  1 
ATOM   14334 O OG1 . THR E 1 229 ? 82.623  -14.007 80.870  1.00 43.54  ? 229 THR E OG1 1 
ATOM   14335 C CG2 . THR E 1 229 ? 80.860  -15.136 79.675  1.00 28.55  ? 229 THR E CG2 1 
ATOM   14336 N N   . LEU E 1 230 ? 79.842  -11.608 78.367  1.00 36.98  ? 230 LEU E N   1 
ATOM   14337 C CA  . LEU E 1 230 ? 78.590  -11.333 77.678  1.00 38.43  ? 230 LEU E CA  1 
ATOM   14338 C C   . LEU E 1 230 ? 78.841  -10.766 76.288  1.00 35.68  ? 230 LEU E C   1 
ATOM   14339 O O   . LEU E 1 230 ? 78.168  -11.152 75.329  1.00 34.58  ? 230 LEU E O   1 
ATOM   14340 C CB  . LEU E 1 230 ? 77.728  -10.394 78.520  1.00 34.64  ? 230 LEU E CB  1 
ATOM   14341 C CG  . LEU E 1 230 ? 77.268  -11.053 79.821  1.00 35.14  ? 230 LEU E CG  1 
ATOM   14342 C CD1 . LEU E 1 230 ? 76.796  -10.022 80.781  1.00 31.13  ? 230 LEU E CD1 1 
ATOM   14343 C CD2 . LEU E 1 230 ? 76.171  -12.085 79.602  1.00 34.67  ? 230 LEU E CD2 1 
ATOM   14344 N N   . TRP E 1 231 ? 79.838  -9.892  76.150  1.00 37.72  ? 231 TRP E N   1 
ATOM   14345 C CA  . TRP E 1 231 ? 80.156  -9.324  74.842  1.00 37.71  ? 231 TRP E CA  1 
ATOM   14346 C C   . TRP E 1 231 ? 80.678  -10.388 73.872  1.00 40.33  ? 231 TRP E C   1 
ATOM   14347 O O   . TRP E 1 231 ? 80.213  -10.479 72.727  1.00 36.79  ? 231 TRP E O   1 
ATOM   14348 C CB  . TRP E 1 231 ? 81.164  -8.186  75.006  1.00 34.21  ? 231 TRP E CB  1 
ATOM   14349 C CG  . TRP E 1 231 ? 81.417  -7.402  73.765  1.00 30.54  ? 231 TRP E CG  1 
ATOM   14350 C CD1 . TRP E 1 231 ? 82.539  -7.431  72.996  1.00 28.60  ? 231 TRP E CD1 1 
ATOM   14351 C CD2 . TRP E 1 231 ? 80.528  -6.471  73.143  1.00 27.78  ? 231 TRP E CD2 1 
ATOM   14352 N NE1 . TRP E 1 231 ? 82.410  -6.565  71.939  1.00 28.92  ? 231 TRP E NE1 1 
ATOM   14353 C CE2 . TRP E 1 231 ? 81.179  -5.966  72.008  1.00 31.21  ? 231 TRP E CE2 1 
ATOM   14354 C CE3 . TRP E 1 231 ? 79.247  -6.007  73.444  1.00 32.25  ? 231 TRP E CE3 1 
ATOM   14355 C CZ2 . TRP E 1 231 ? 80.597  -5.014  71.178  1.00 29.08  ? 231 TRP E CZ2 1 
ATOM   14356 C CZ3 . TRP E 1 231 ? 78.667  -5.072  72.610  1.00 31.24  ? 231 TRP E CZ3 1 
ATOM   14357 C CH2 . TRP E 1 231 ? 79.338  -4.591  71.491  1.00 27.90  ? 231 TRP E CH2 1 
ATOM   14358 N N   . SER E 1 232 ? 81.645  -11.204 74.305  1.00 38.99  ? 232 SER E N   1 
ATOM   14359 C CA  . SER E 1 232 ? 82.209  -12.223 73.423  1.00 36.57  ? 232 SER E CA  1 
ATOM   14360 C C   . SER E 1 232 ? 81.205  -13.306 73.033  1.00 41.65  ? 232 SER E C   1 
ATOM   14361 O O   . SER E 1 232 ? 81.389  -13.979 72.012  1.00 38.47  ? 232 SER E O   1 
ATOM   14362 C CB  . SER E 1 232 ? 83.417  -12.866 74.094  1.00 34.60  ? 232 SER E CB  1 
ATOM   14363 O OG  . SER E 1 232 ? 84.368  -11.867 74.428  1.00 47.17  ? 232 SER E OG  1 
ATOM   14364 N N   . GLN E 1 233 ? 80.163  -13.510 73.824  1.00 41.39  ? 233 GLN E N   1 
ATOM   14365 C CA  . GLN E 1 233 ? 79.233  -14.584 73.529  1.00 36.41  ? 233 GLN E CA  1 
ATOM   14366 C C   . GLN E 1 233 ? 78.045  -14.141 72.682  1.00 37.81  ? 233 GLN E C   1 
ATOM   14367 O O   . GLN E 1 233 ? 77.428  -14.985 72.024  1.00 48.51  ? 233 GLN E O   1 
ATOM   14368 C CB  . GLN E 1 233 ? 78.730  -15.206 74.828  1.00 37.87  ? 233 GLN E CB  1 
ATOM   14369 C CG  . GLN E 1 233 ? 79.702  -16.174 75.449  1.00 46.85  ? 233 GLN E CG  1 
ATOM   14370 C CD  . GLN E 1 233 ? 79.101  -17.553 75.595  1.00 57.88  ? 233 GLN E CD  1 
ATOM   14371 O OE1 . GLN E 1 233 ? 77.981  -17.706 76.104  1.00 54.41  ? 233 GLN E OE1 1 
ATOM   14372 N NE2 . GLN E 1 233 ? 79.821  -18.571 75.110  1.00 58.22  ? 233 GLN E NE2 1 
ATOM   14373 N N   . LEU E 1 234 ? 77.715  -12.853 72.663  1.00 35.64  ? 234 LEU E N   1 
ATOM   14374 C CA  . LEU E 1 234 ? 76.519  -12.374 71.983  1.00 34.47  ? 234 LEU E CA  1 
ATOM   14375 C C   . LEU E 1 234 ? 76.795  -11.455 70.790  1.00 33.78  ? 234 LEU E C   1 
ATOM   14376 O O   . LEU E 1 234 ? 75.840  -10.960 70.182  1.00 37.12  ? 234 LEU E O   1 
ATOM   14377 C CB  . LEU E 1 234 ? 75.607  -11.664 72.993  1.00 39.38  ? 234 LEU E CB  1 
ATOM   14378 C CG  . LEU E 1 234 ? 75.295  -12.399 74.302  1.00 36.88  ? 234 LEU E CG  1 
ATOM   14379 C CD1 . LEU E 1 234 ? 74.589  -11.487 75.287  1.00 34.14  ? 234 LEU E CD1 1 
ATOM   14380 C CD2 . LEU E 1 234 ? 74.461  -13.628 74.025  1.00 37.83  ? 234 LEU E CD2 1 
ATOM   14381 N N   . THR E 1 235 ? 78.060  -11.233 70.424  1.00 33.58  ? 235 THR E N   1 
ATOM   14382 C CA  . THR E 1 235 ? 78.447  -10.419 69.277  1.00 34.89  ? 235 THR E CA  1 
ATOM   14383 C C   . THR E 1 235 ? 79.217  -11.265 68.272  1.00 35.84  ? 235 THR E C   1 
ATOM   14384 O O   . THR E 1 235 ? 79.846  -12.262 68.632  1.00 31.35  ? 235 THR E O   1 
ATOM   14385 C CB  . THR E 1 235 ? 79.338  -9.234  69.670  1.00 30.51  ? 235 THR E CB  1 
ATOM   14386 O OG1 . THR E 1 235 ? 80.470  -9.715  70.398  1.00 33.79  ? 235 THR E OG1 1 
ATOM   14387 C CG2 . THR E 1 235 ? 78.585  -8.233  70.514  1.00 33.37  ? 235 THR E CG2 1 
ATOM   14388 N N   . ASP E 1 236 ? 79.167  -10.856 67.006  1.00 34.21  ? 236 ASP E N   1 
ATOM   14389 C CA  . ASP E 1 236 ? 79.953  -11.487 65.945  1.00 38.44  ? 236 ASP E CA  1 
ATOM   14390 C C   . ASP E 1 236 ? 80.406  -10.379 65.003  1.00 37.52  ? 236 ASP E C   1 
ATOM   14391 O O   . ASP E 1 236 ? 80.332  -9.193  65.342  1.00 42.90  ? 236 ASP E O   1 
ATOM   14392 C CB  . ASP E 1 236 ? 79.164  -12.611 65.245  1.00 36.68  ? 236 ASP E CB  1 
ATOM   14393 C CG  . ASP E 1 236 ? 77.754  -12.194 64.828  1.00 37.15  ? 236 ASP E CG  1 
ATOM   14394 O OD1 . ASP E 1 236 ? 77.518  -11.000 64.534  1.00 40.84  ? 236 ASP E OD1 1 
ATOM   14395 O OD2 . ASP E 1 236 ? 76.873  -13.071 64.764  1.00 34.81  ? 236 ASP E OD2 1 
ATOM   14396 N N   . THR E 1 237 ? 80.894  -10.751 63.817  1.00 39.76  ? 237 THR E N   1 
ATOM   14397 C CA  . THR E 1 237 ? 81.366  -9.733  62.878  1.00 36.98  ? 237 THR E CA  1 
ATOM   14398 C C   . THR E 1 237 ? 80.239  -8.802  62.431  1.00 38.79  ? 237 THR E C   1 
ATOM   14399 O O   . THR E 1 237 ? 80.455  -7.594  62.250  1.00 36.13  ? 237 THR E O   1 
ATOM   14400 C CB  . THR E 1 237 ? 82.023  -10.400 61.669  1.00 44.04  ? 237 THR E CB  1 
ATOM   14401 O OG1 . THR E 1 237 ? 83.053  -11.286 62.125  1.00 52.10  ? 237 THR E OG1 1 
ATOM   14402 C CG2 . THR E 1 237 ? 82.653  -9.349  60.751  1.00 37.49  ? 237 THR E CG2 1 
ATOM   14403 N N   . GLN E 1 238 ? 79.030  -9.321  62.289  1.00 35.73  ? 238 GLN E N   1 
ATOM   14404 C CA  . GLN E 1 238 ? 77.923  -8.510  61.808  1.00 40.09  ? 238 GLN E CA  1 
ATOM   14405 C C   . GLN E 1 238 ? 77.133  -7.842  62.934  1.00 41.91  ? 238 GLN E C   1 
ATOM   14406 O O   . GLN E 1 238 ? 76.354  -6.918  62.666  1.00 36.95  ? 238 GLN E O   1 
ATOM   14407 C CB  . GLN E 1 238 ? 76.970  -9.359  60.953  1.00 36.55  ? 238 GLN E CB  1 
ATOM   14408 C CG  . GLN E 1 238 ? 77.611  -10.078 59.764  1.00 38.93  ? 238 GLN E CG  1 
ATOM   14409 C CD  . GLN E 1 238 ? 78.498  -11.253 60.187  1.00 40.97  ? 238 GLN E CD  1 
ATOM   14410 O OE1 . GLN E 1 238 ? 79.661  -11.334 59.797  1.00 50.12  ? 238 GLN E OE1 1 
ATOM   14411 N NE2 . GLN E 1 238 ? 77.962  -12.139 61.024  1.00 41.80  ? 238 GLN E NE2 1 
ATOM   14412 N N   . ASN E 1 239 ? 77.325  -8.254  64.183  1.00 34.88  ? 239 ASN E N   1 
ATOM   14413 C CA  . ASN E 1 239 ? 76.488  -7.773  65.277  1.00 34.73  ? 239 ASN E CA  1 
ATOM   14414 C C   . ASN E 1 239 ? 77.375  -7.182  66.356  1.00 32.30  ? 239 ASN E C   1 
ATOM   14415 O O   . ASN E 1 239 ? 77.942  -7.903  67.181  1.00 30.15  ? 239 ASN E O   1 
ATOM   14416 C CB  . ASN E 1 239 ? 75.610  -8.891  65.803  1.00 31.06  ? 239 ASN E CB  1 
ATOM   14417 C CG  . ASN E 1 239 ? 74.657  -9.368  64.759  1.00 36.82  ? 239 ASN E CG  1 
ATOM   14418 O OD1 . ASN E 1 239 ? 73.657  -8.706  64.470  1.00 37.78  ? 239 ASN E OD1 1 
ATOM   14419 N ND2 . ASN E 1 239 ? 74.980  -10.489 64.135  1.00 40.32  ? 239 ASN E ND2 1 
ATOM   14420 N N   . GLN E 1 240 ? 77.484  -5.858  66.337  1.00 30.98  ? 240 GLN E N   1 
ATOM   14421 C CA  . GLN E 1 240 ? 78.337  -5.138  67.260  1.00 32.45  ? 240 GLN E CA  1 
ATOM   14422 C C   . GLN E 1 240 ? 77.517  -4.366  68.281  1.00 32.46  ? 240 GLN E C   1 
ATOM   14423 O O   . GLN E 1 240 ? 77.997  -3.369  68.825  1.00 27.32  ? 240 GLN E O   1 
ATOM   14424 C CB  . GLN E 1 240 ? 79.266  -4.215  66.478  1.00 37.53  ? 240 GLN E CB  1 
ATOM   14425 C CG  . GLN E 1 240 ? 80.525  -4.906  65.974  1.00 34.13  ? 240 GLN E CG  1 
ATOM   14426 C CD  . GLN E 1 240 ? 81.297  -5.585  67.083  1.00 39.29  ? 240 GLN E CD  1 
ATOM   14427 O OE1 . GLN E 1 240 ? 81.894  -4.921  67.941  1.00 40.86  ? 240 GLN E OE1 1 
ATOM   14428 N NE2 . GLN E 1 240 ? 81.299  -6.914  67.071  1.00 37.02  ? 240 GLN E NE2 1 
ATOM   14429 N N   . PHE E 1 241 ? 76.274  -4.804  68.523  1.00 33.47  ? 241 PHE E N   1 
ATOM   14430 C CA  . PHE E 1 241 ? 75.402  -4.287  69.571  1.00 28.21  ? 241 PHE E CA  1 
ATOM   14431 C C   . PHE E 1 241 ? 74.973  -5.450  70.444  1.00 30.01  ? 241 PHE E C   1 
ATOM   14432 O O   . PHE E 1 241 ? 74.821  -6.582  69.967  1.00 30.47  ? 241 PHE E O   1 
ATOM   14433 C CB  . PHE E 1 241 ? 74.102  -3.645  69.030  1.00 29.18  ? 241 PHE E CB  1 
ATOM   14434 C CG  . PHE E 1 241 ? 74.283  -2.353  68.274  1.00 29.66  ? 241 PHE E CG  1 
ATOM   14435 C CD1 . PHE E 1 241 ? 75.006  -1.303  68.809  1.00 27.67  ? 241 PHE E CD1 1 
ATOM   14436 C CD2 . PHE E 1 241 ? 73.646  -2.170  67.055  1.00 30.51  ? 241 PHE E CD2 1 
ATOM   14437 C CE1 . PHE E 1 241 ? 75.151  -0.107  68.118  1.00 29.11  ? 241 PHE E CE1 1 
ATOM   14438 C CE2 . PHE E 1 241 ? 73.768  -0.980  66.364  1.00 29.15  ? 241 PHE E CE2 1 
ATOM   14439 C CZ  . PHE E 1 241 ? 74.527  0.058   66.898  1.00 31.22  ? 241 PHE E CZ  1 
ATOM   14440 N N   . ILE E 1 242 ? 74.710  -5.152  71.708  1.00 26.99  ? 242 ILE E N   1 
ATOM   14441 C CA  . ILE E 1 242 ? 74.097  -6.095  72.639  1.00 26.40  ? 242 ILE E CA  1 
ATOM   14442 C C   . ILE E 1 242 ? 73.065  -5.324  73.439  1.00 28.03  ? 242 ILE E C   1 
ATOM   14443 O O   . ILE E 1 242 ? 73.320  -4.202  73.881  1.00 33.86  ? 242 ILE E O   1 
ATOM   14444 C CB  . ILE E 1 242 ? 75.147  -6.746  73.567  1.00 31.55  ? 242 ILE E CB  1 
ATOM   14445 C CG1 . ILE E 1 242 ? 75.700  -8.020  72.962  1.00 31.29  ? 242 ILE E CG1 1 
ATOM   14446 C CG2 . ILE E 1 242 ? 74.607  -7.041  74.946  1.00 32.35  ? 242 ILE E CG2 1 
ATOM   14447 C CD1 . ILE E 1 242 ? 76.790  -8.598  73.835  1.00 40.69  ? 242 ILE E CD1 1 
ATOM   14448 N N   . THR E 1 243 ? 71.893  -5.903  73.606  1.00 24.74  ? 243 THR E N   1 
ATOM   14449 C CA  . THR E 1 243 ? 70.865  -5.265  74.399  1.00 26.82  ? 243 THR E CA  1 
ATOM   14450 C C   . THR E 1 243 ? 70.969  -5.768  75.835  1.00 22.85  ? 243 THR E C   1 
ATOM   14451 O O   . THR E 1 243 ? 71.219  -6.952  76.069  1.00 26.60  ? 243 THR E O   1 
ATOM   14452 C CB  . THR E 1 243 ? 69.493  -5.539  73.775  1.00 28.11  ? 243 THR E CB  1 
ATOM   14453 O OG1 . THR E 1 243 ? 68.986  -4.323  73.210  1.00 31.51  ? 243 THR E OG1 1 
ATOM   14454 C CG2 . THR E 1 243 ? 68.525  -6.078  74.774  1.00 30.92  ? 243 THR E CG2 1 
ATOM   14455 N N   . VAL E 1 244 ? 70.843  -4.845  76.788  1.00 23.19  ? 244 VAL E N   1 
ATOM   14456 C CA  . VAL E 1 244 ? 71.012  -5.105  78.217  1.00 24.86  ? 244 VAL E CA  1 
ATOM   14457 C C   . VAL E 1 244 ? 69.822  -4.484  78.927  1.00 27.74  ? 244 VAL E C   1 
ATOM   14458 O O   . VAL E 1 244 ? 69.634  -3.264  78.841  1.00 27.58  ? 244 VAL E O   1 
ATOM   14459 C CB  . VAL E 1 244 ? 72.320  -4.496  78.757  1.00 24.66  ? 244 VAL E CB  1 
ATOM   14460 C CG1 . VAL E 1 244 ? 72.527  -4.886  80.205  1.00 29.79  ? 244 VAL E CG1 1 
ATOM   14461 C CG2 . VAL E 1 244 ? 73.515  -4.907  77.908  1.00 25.09  ? 244 VAL E CG2 1 
ATOM   14462 N N   . GLU E 1 245 ? 69.024  -5.302  79.638  1.00 25.32  ? 245 GLU E N   1 
ATOM   14463 C CA  . GLU E 1 245 ? 67.757  -4.816  80.191  1.00 29.41  ? 245 GLU E CA  1 
ATOM   14464 C C   . GLU E 1 245 ? 67.477  -5.341  81.593  1.00 28.46  ? 245 GLU E C   1 
ATOM   14465 O O   . GLU E 1 245 ? 67.881  -6.444  81.959  1.00 30.95  ? 245 GLU E O   1 
ATOM   14466 C CB  . GLU E 1 245 ? 66.541  -5.181  79.306  1.00 28.55  ? 245 GLU E CB  1 
ATOM   14467 C CG  . GLU E 1 245 ? 66.797  -5.229  77.813  1.00 35.07  ? 245 GLU E CG  1 
ATOM   14468 C CD  . GLU E 1 245 ? 65.521  -5.386  76.986  1.00 36.15  ? 245 GLU E CD  1 
ATOM   14469 O OE1 . GLU E 1 245 ? 64.718  -6.295  77.328  1.00 36.93  ? 245 GLU E OE1 1 
ATOM   14470 O OE2 . GLU E 1 245 ? 65.331  -4.606  76.013  1.00 31.04  ? 245 GLU E OE2 1 
ATOM   14471 N N   . THR E 1 246 ? 66.735  -4.539  82.358  1.00 29.12  ? 246 THR E N   1 
ATOM   14472 C CA  . THR E 1 246 ? 66.121  -4.998  83.603  1.00 28.08  ? 246 THR E CA  1 
ATOM   14473 C C   . THR E 1 246 ? 65.109  -6.102  83.307  1.00 31.55  ? 246 THR E C   1 
ATOM   14474 O O   . THR E 1 246 ? 64.214  -5.921  82.476  1.00 28.26  ? 246 THR E O   1 
ATOM   14475 C CB  . THR E 1 246 ? 65.419  -3.828  84.300  1.00 26.53  ? 246 THR E CB  1 
ATOM   14476 O OG1 . THR E 1 246 ? 66.393  -2.897  84.790  1.00 30.80  ? 246 THR E OG1 1 
ATOM   14477 C CG2 . THR E 1 246 ? 64.525  -4.306  85.430  1.00 26.63  ? 246 THR E CG2 1 
ATOM   14478 N N   . TYR E 1 247 ? 65.244  -7.244  83.988  1.00 30.27  ? 247 TYR E N   1 
ATOM   14479 C CA  . TYR E 1 247 ? 64.379  -8.396  83.764  1.00 25.83  ? 247 TYR E CA  1 
ATOM   14480 C C   . TYR E 1 247 ? 63.285  -8.446  84.828  1.00 34.30  ? 247 TYR E C   1 
ATOM   14481 O O   . TYR E 1 247 ? 63.556  -8.256  86.018  1.00 36.40  ? 247 TYR E O   1 
ATOM   14482 C CB  . TYR E 1 247 ? 65.195  -9.692  83.764  1.00 28.42  ? 247 TYR E CB  1 
ATOM   14483 C CG  . TYR E 1 247 ? 64.425  -10.926 83.346  1.00 37.06  ? 247 TYR E CG  1 
ATOM   14484 C CD1 . TYR E 1 247 ? 63.681  -11.651 84.267  1.00 39.73  ? 247 TYR E CD1 1 
ATOM   14485 C CD2 . TYR E 1 247 ? 64.444  -11.372 82.030  1.00 36.09  ? 247 TYR E CD2 1 
ATOM   14486 C CE1 . TYR E 1 247 ? 62.977  -12.794 83.891  1.00 44.59  ? 247 TYR E CE1 1 
ATOM   14487 C CE2 . TYR E 1 247 ? 63.742  -12.511 81.644  1.00 34.79  ? 247 TYR E CE2 1 
ATOM   14488 C CZ  . TYR E 1 247 ? 63.005  -13.220 82.579  1.00 45.90  ? 247 TYR E CZ  1 
ATOM   14489 O OH  . TYR E 1 247 ? 62.303  -14.359 82.202  1.00 47.19  ? 247 TYR E OH  1 
ATOM   14490 N N   . HIS E 1 248 ? 62.050  -8.692  84.403  1.00 34.33  ? 248 HIS E N   1 
ATOM   14491 C CA  . HIS E 1 248 ? 60.927  -8.851  85.320  1.00 33.91  ? 248 HIS E CA  1 
ATOM   14492 C C   . HIS E 1 248 ? 60.374  -10.258 85.166  1.00 34.18  ? 248 HIS E C   1 
ATOM   14493 O O   . HIS E 1 248 ? 60.191  -10.733 84.043  1.00 35.73  ? 248 HIS E O   1 
ATOM   14494 C CB  . HIS E 1 248 ? 59.818  -7.821  85.047  1.00 28.64  ? 248 HIS E CB  1 
ATOM   14495 C CG  . HIS E 1 248 ? 60.287  -6.398  85.068  1.00 29.28  ? 248 HIS E CG  1 
ATOM   14496 N ND1 . HIS E 1 248 ? 60.251  -5.615  86.200  1.00 33.78  ? 248 HIS E ND1 1 
ATOM   14497 C CD2 . HIS E 1 248 ? 60.823  -5.624  84.097  1.00 32.52  ? 248 HIS E CD2 1 
ATOM   14498 C CE1 . HIS E 1 248 ? 60.741  -4.421  85.925  1.00 31.75  ? 248 HIS E CE1 1 
ATOM   14499 N NE2 . HIS E 1 248 ? 61.090  -4.399  84.652  1.00 31.07  ? 248 HIS E NE2 1 
ATOM   14500 N N   . ARG E 1 249 ? 60.128  -10.930 86.282  1.00 40.42  ? 249 ARG E N   1 
ATOM   14501 C CA  . ARG E 1 249 ? 59.280  -12.113 86.240  1.00 43.83  ? 249 ARG E CA  1 
ATOM   14502 C C   . ARG E 1 249 ? 57.855  -11.659 85.963  1.00 42.39  ? 249 ARG E C   1 
ATOM   14503 O O   . ARG E 1 249 ? 57.407  -10.643 86.498  1.00 44.72  ? 249 ARG E O   1 
ATOM   14504 C CB  . ARG E 1 249 ? 59.358  -12.890 87.555  1.00 48.44  ? 249 ARG E CB  1 
ATOM   14505 C CG  . ARG E 1 249 ? 60.653  -13.690 87.740  1.00 60.51  ? 249 ARG E CG  1 
ATOM   14506 C CD  . ARG E 1 249 ? 60.386  -15.010 88.467  1.00 66.96  ? 249 ARG E CD  1 
ATOM   14507 N NE  . ARG E 1 249 ? 61.602  -15.720 88.849  1.00 68.73  ? 249 ARG E NE  1 
ATOM   14508 C CZ  . ARG E 1 249 ? 62.340  -16.452 88.023  1.00 75.53  ? 249 ARG E CZ  1 
ATOM   14509 N NH1 . ARG E 1 249 ? 62.048  -16.551 86.736  1.00 72.92  ? 249 ARG E NH1 1 
ATOM   14510 N NH2 . ARG E 1 249 ? 63.393  -17.109 88.502  1.00 76.36  ? 249 ARG E NH2 1 
ATOM   14511 N N   . ALA E 1 250 ? 57.148  -12.386 85.103  1.00 41.60  ? 250 ALA E N   1 
ATOM   14512 C CA  . ALA E 1 250 ? 55.909  -11.868 84.536  1.00 43.89  ? 250 ALA E CA  1 
ATOM   14513 C C   . ALA E 1 250 ? 54.694  -12.649 85.017  1.00 45.33  ? 250 ALA E C   1 
ATOM   14514 O O   . ALA E 1 250 ? 54.760  -13.860 85.246  1.00 37.43  ? 250 ALA E O   1 
ATOM   14515 C CB  . ALA E 1 250 ? 55.945  -11.890 83.003  1.00 41.61  ? 250 ALA E CB  1 
ATOM   14516 N N   . ASP E 1 251 ? 53.577  -11.927 85.160  1.00 43.93  ? 251 ASP E N   1 
ATOM   14517 C CA  . ASP E 1 251 ? 52.293  -12.582 85.383  1.00 44.31  ? 251 ASP E CA  1 
ATOM   14518 C C   . ASP E 1 251 ? 51.788  -13.234 84.105  1.00 40.06  ? 251 ASP E C   1 
ATOM   14519 O O   . ASP E 1 251 ? 51.212  -14.327 84.140  1.00 44.98  ? 251 ASP E O   1 
ATOM   14520 C CB  . ASP E 1 251 ? 51.274  -11.566 85.909  1.00 49.53  ? 251 ASP E CB  1 
ATOM   14521 C CG  . ASP E 1 251 ? 50.080  -12.225 86.578  1.00 52.01  ? 251 ASP E CG  1 
ATOM   14522 O OD1 . ASP E 1 251 ? 49.188  -12.731 85.860  1.00 55.53  ? 251 ASP E OD1 1 
ATOM   14523 O OD2 . ASP E 1 251 ? 50.037  -12.241 87.826  1.00 60.06  ? 251 ASP E OD2 1 
ATOM   14524 N N   . GLN E 1 252 ? 51.995  -12.580 82.969  1.00 41.05  ? 252 GLN E N   1 
ATOM   14525 C CA  . GLN E 1 252 ? 51.527  -13.084 81.690  1.00 41.29  ? 252 GLN E CA  1 
ATOM   14526 C C   . GLN E 1 252 ? 52.464  -12.551 80.619  1.00 39.94  ? 252 GLN E C   1 
ATOM   14527 O O   . GLN E 1 252 ? 52.899  -11.396 80.689  1.00 36.98  ? 252 GLN E O   1 
ATOM   14528 C CB  . GLN E 1 252 ? 50.066  -12.678 81.430  1.00 41.93  ? 252 GLN E CB  1 
ATOM   14529 C CG  . GLN E 1 252 ? 49.821  -11.181 81.520  1.00 38.16  ? 252 GLN E CG  1 
ATOM   14530 C CD  . GLN E 1 252 ? 48.586  -10.789 82.340  1.00 45.23  ? 252 GLN E CD  1 
ATOM   14531 O OE1 . GLN E 1 252 ? 48.582  -10.902 83.575  1.00 44.95  ? 252 GLN E OE1 1 
ATOM   14532 N NE2 . GLN E 1 252 ? 47.554  -10.281 81.658  1.00 30.57  ? 252 GLN E NE2 1 
ATOM   14533 N N   . ARG E 1 253 ? 52.778  -13.408 79.643  1.00 39.62  ? 253 ARG E N   1 
ATOM   14534 C CA  . ARG E 1 253 ? 53.864  -13.192 78.692  1.00 40.06  ? 253 ARG E CA  1 
ATOM   14535 C C   . ARG E 1 253 ? 53.354  -13.377 77.251  1.00 42.38  ? 253 ARG E C   1 
ATOM   14536 O O   . ARG E 1 253 ? 53.792  -14.262 76.516  1.00 53.16  ? 253 ARG E O   1 
ATOM   14537 C CB  . ARG E 1 253 ? 55.017  -14.149 79.010  1.00 47.84  ? 253 ARG E CB  1 
ATOM   14538 C CG  . ARG E 1 253 ? 56.417  -13.671 78.574  1.00 57.00  ? 253 ARG E CG  1 
ATOM   14539 C CD  . ARG E 1 253 ? 57.559  -14.660 78.890  1.00 61.00  ? 253 ARG E CD  1 
ATOM   14540 N NE  . ARG E 1 253 ? 57.531  -15.179 80.256  1.00 53.53  ? 253 ARG E NE  1 
ATOM   14541 C CZ  . ARG E 1 253 ? 56.889  -16.281 80.624  1.00 65.02  ? 253 ARG E CZ  1 
ATOM   14542 N NH1 . ARG E 1 253 ? 56.185  -16.993 79.756  1.00 66.36  ? 253 ARG E NH1 1 
ATOM   14543 N NH2 . ARG E 1 253 ? 56.958  -16.682 81.893  1.00 64.27  ? 253 ARG E NH2 1 
ATOM   14544 N N   . PHE E 1 254 ? 52.433  -12.506 76.843  1.00 31.29  ? 254 PHE E N   1 
ATOM   14545 C CA  . PHE E 1 254 ? 51.752  -12.598 75.556  1.00 30.97  ? 254 PHE E CA  1 
ATOM   14546 C C   . PHE E 1 254 ? 52.641  -12.243 74.371  1.00 31.29  ? 254 PHE E C   1 
ATOM   14547 O O   . PHE E 1 254 ? 53.689  -11.610 74.502  1.00 30.08  ? 254 PHE E O   1 
ATOM   14548 C CB  . PHE E 1 254 ? 50.573  -11.641 75.509  1.00 25.42  ? 254 PHE E CB  1 
ATOM   14549 C CG  . PHE E 1 254 ? 50.960  -10.202 75.690  1.00 28.94  ? 254 PHE E CG  1 
ATOM   14550 C CD1 . PHE E 1 254 ? 51.220  -9.699  76.945  1.00 28.03  ? 254 PHE E CD1 1 
ATOM   14551 C CD2 . PHE E 1 254 ? 51.044  -9.346  74.606  1.00 26.78  ? 254 PHE E CD2 1 
ATOM   14552 C CE1 . PHE E 1 254 ? 51.565  -8.365  77.119  1.00 29.23  ? 254 PHE E CE1 1 
ATOM   14553 C CE2 . PHE E 1 254 ? 51.390  -8.008  74.777  1.00 31.03  ? 254 PHE E CE2 1 
ATOM   14554 C CZ  . PHE E 1 254 ? 51.652  -7.518  76.034  1.00 23.44  ? 254 PHE E CZ  1 
ATOM   14555 N N   . PHE E 1 255 ? 52.173  -12.635 73.184  1.00 28.04  ? 255 PHE E N   1 
ATOM   14556 C CA  . PHE E 1 255 ? 52.522  -11.933 71.964  1.00 26.31  ? 255 PHE E CA  1 
ATOM   14557 C C   . PHE E 1 255 ? 51.261  -11.755 71.122  1.00 27.57  ? 255 PHE E C   1 
ATOM   14558 O O   . PHE E 1 255 ? 50.328  -12.559 71.200  1.00 25.32  ? 255 PHE E O   1 
ATOM   14559 C CB  . PHE E 1 255 ? 53.666  -12.627 71.196  1.00 25.98  ? 255 PHE E CB  1 
ATOM   14560 C CG  . PHE E 1 255 ? 53.285  -13.911 70.470  1.00 27.25  ? 255 PHE E CG  1 
ATOM   14561 C CD1 . PHE E 1 255 ? 53.339  -15.135 71.121  1.00 25.04  ? 255 PHE E CD1 1 
ATOM   14562 C CD2 . PHE E 1 255 ? 52.991  -13.901 69.112  1.00 27.60  ? 255 PHE E CD2 1 
ATOM   14563 C CE1 . PHE E 1 255 ? 53.044  -16.323 70.447  1.00 30.87  ? 255 PHE E CE1 1 
ATOM   14564 C CE2 . PHE E 1 255 ? 52.690  -15.098 68.425  1.00 24.32  ? 255 PHE E CE2 1 
ATOM   14565 C CZ  . PHE E 1 255 ? 52.710  -16.296 69.095  1.00 22.27  ? 255 PHE E CZ  1 
ATOM   14566 N N   . PHE E 1 256 ? 51.232  -10.647 70.367  1.00 25.94  ? 256 PHE E N   1 
ATOM   14567 C CA  . PHE E 1 256 ? 50.216  -10.335 69.369  1.00 23.81  ? 256 PHE E CA  1 
ATOM   14568 C C   . PHE E 1 256 ? 50.830  -10.448 67.980  1.00 26.55  ? 256 PHE E C   1 
ATOM   14569 O O   . PHE E 1 256 ? 51.975  -10.035 67.764  1.00 23.65  ? 256 PHE E O   1 
ATOM   14570 C CB  . PHE E 1 256 ? 49.653  -8.918  69.539  1.00 21.32  ? 256 PHE E CB  1 
ATOM   14571 C CG  . PHE E 1 256 ? 49.119  -8.624  70.911  1.00 25.38  ? 256 PHE E CG  1 
ATOM   14572 C CD1 . PHE E 1 256 ? 48.673  -9.635  71.742  1.00 25.36  ? 256 PHE E CD1 1 
ATOM   14573 C CD2 . PHE E 1 256 ? 49.063  -7.323  71.372  1.00 25.69  ? 256 PHE E CD2 1 
ATOM   14574 C CE1 . PHE E 1 256 ? 48.189  -9.343  73.016  1.00 23.83  ? 256 PHE E CE1 1 
ATOM   14575 C CE2 . PHE E 1 256 ? 48.581  -7.038  72.641  1.00 30.60  ? 256 PHE E CE2 1 
ATOM   14576 C CZ  . PHE E 1 256 ? 48.152  -8.042  73.458  1.00 22.27  ? 256 PHE E CZ  1 
ATOM   14577 N N   . GLU E 1 257 ? 50.072  -11.017 67.043  1.00 20.30  ? 257 GLU E N   1 
ATOM   14578 C CA  . GLU E 1 257 ? 50.488  -11.145 65.659  1.00 18.79  ? 257 GLU E CA  1 
ATOM   14579 C C   . GLU E 1 257 ? 49.527  -10.344 64.802  1.00 20.75  ? 257 GLU E C   1 
ATOM   14580 O O   . GLU E 1 257 ? 48.331  -10.289 65.100  1.00 22.16  ? 257 GLU E O   1 
ATOM   14581 C CB  . GLU E 1 257 ? 50.488  -12.610 65.210  1.00 22.30  ? 257 GLU E CB  1 
ATOM   14582 C CG  . GLU E 1 257 ? 51.287  -12.891 63.962  1.00 15.20  ? 257 GLU E CG  1 
ATOM   14583 C CD  . GLU E 1 257 ? 51.681  -14.361 63.824  1.00 17.07  ? 257 GLU E CD  1 
ATOM   14584 O OE1 . GLU E 1 257 ? 51.034  -15.241 64.445  1.00 21.58  ? 257 GLU E OE1 1 
ATOM   14585 O OE2 . GLU E 1 257 ? 52.642  -14.643 63.081  1.00 18.99  ? 257 GLU E OE2 1 
ATOM   14586 N N   . TYR E 1 258 ? 50.066  -9.734  63.742  1.00 19.92  ? 258 TYR E N   1 
ATOM   14587 C CA  . TYR E 1 258 ? 49.361  -8.828  62.843  1.00 19.44  ? 258 TYR E CA  1 
ATOM   14588 C C   . TYR E 1 258 ? 49.719  -9.148  61.398  1.00 18.98  ? 258 TYR E C   1 
ATOM   14589 O O   . TYR E 1 258 ? 50.774  -9.716  61.099  1.00 20.09  ? 258 TYR E O   1 
ATOM   14590 C CB  . TYR E 1 258 ? 49.720  -7.344  63.085  1.00 20.83  ? 258 TYR E CB  1 
ATOM   14591 C CG  . TYR E 1 258 ? 49.449  -6.843  64.487  1.00 22.91  ? 258 TYR E CG  1 
ATOM   14592 C CD1 . TYR E 1 258 ? 50.285  -7.188  65.539  1.00 19.92  ? 258 TYR E CD1 1 
ATOM   14593 C CD2 . TYR E 1 258 ? 48.357  -6.025  64.751  1.00 18.90  ? 258 TYR E CD2 1 
ATOM   14594 C CE1 . TYR E 1 258 ? 50.043  -6.744  66.810  1.00 25.27  ? 258 TYR E CE1 1 
ATOM   14595 C CE2 . TYR E 1 258 ? 48.094  -5.582  66.027  1.00 18.00  ? 258 TYR E CE2 1 
ATOM   14596 C CZ  . TYR E 1 258 ? 48.945  -5.937  67.050  1.00 22.94  ? 258 TYR E CZ  1 
ATOM   14597 O OH  . TYR E 1 258 ? 48.708  -5.513  68.328  1.00 20.80  ? 258 TYR E OH  1 
ATOM   14598 N N   . HIS E 1 259 ? 48.841  -8.728  60.502  1.00 19.67  ? 259 HIS E N   1 
ATOM   14599 C CA  . HIS E 1 259 ? 49.107  -8.710  59.073  1.00 23.14  ? 259 HIS E CA  1 
ATOM   14600 C C   . HIS E 1 259 ? 48.992  -7.277  58.564  1.00 24.25  ? 259 HIS E C   1 
ATOM   14601 O O   . HIS E 1 259 ? 47.979  -6.606  58.803  1.00 21.98  ? 259 HIS E O   1 
ATOM   14602 C CB  . HIS E 1 259 ? 48.131  -9.622  58.335  1.00 22.33  ? 259 HIS E CB  1 
ATOM   14603 C CG  . HIS E 1 259 ? 48.277  -9.573  56.858  1.00 20.80  ? 259 HIS E CG  1 
ATOM   14604 N ND1 . HIS E 1 259 ? 47.530  -8.729  56.069  1.00 25.94  ? 259 HIS E ND1 1 
ATOM   14605 C CD2 . HIS E 1 259 ? 49.091  -10.255 56.022  1.00 21.93  ? 259 HIS E CD2 1 
ATOM   14606 C CE1 . HIS E 1 259 ? 47.877  -8.894  54.806  1.00 26.27  ? 259 HIS E CE1 1 
ATOM   14607 N NE2 . HIS E 1 259 ? 48.821  -9.818  54.751  1.00 24.52  ? 259 HIS E NE2 1 
ATOM   14608 N N   . LEU E 1 260 ? 50.026  -6.822  57.856  1.00 21.43  ? 260 LEU E N   1 
ATOM   14609 C CA  . LEU E 1 260 ? 50.131  -5.459  57.360  1.00 21.45  ? 260 LEU E CA  1 
ATOM   14610 C C   . LEU E 1 260 ? 50.098  -5.467  55.840  1.00 22.86  ? 260 LEU E C   1 
ATOM   14611 O O   . LEU E 1 260 ? 50.897  -6.161  55.204  1.00 23.29  ? 260 LEU E O   1 
ATOM   14612 C CB  . LEU E 1 260 ? 51.435  -4.794  57.835  1.00 19.02  ? 260 LEU E CB  1 
ATOM   14613 C CG  . LEU E 1 260 ? 51.561  -4.284  59.270  1.00 23.95  ? 260 LEU E CG  1 
ATOM   14614 C CD1 . LEU E 1 260 ? 51.116  -5.323  60.277  1.00 20.89  ? 260 LEU E CD1 1 
ATOM   14615 C CD2 . LEU E 1 260 ? 53.001  -3.865  59.579  1.00 24.89  ? 260 LEU E CD2 1 
ATOM   14616 N N   . ASP E 1 261 ? 49.188  -4.693  55.260  1.00 24.82  ? 261 ASP E N   1 
ATOM   14617 C CA  . ASP E 1 261 ? 49.198  -4.434  53.827  1.00 24.64  ? 261 ASP E CA  1 
ATOM   14618 C C   . ASP E 1 261 ? 49.047  -2.923  53.638  1.00 23.88  ? 261 ASP E C   1 
ATOM   14619 O O   . ASP E 1 261 ? 49.243  -2.127  54.569  1.00 22.54  ? 261 ASP E O   1 
ATOM   14620 C CB  . ASP E 1 261 ? 48.144  -5.277  53.088  1.00 23.29  ? 261 ASP E CB  1 
ATOM   14621 C CG  . ASP E 1 261 ? 46.697  -4.997  53.546  1.00 25.86  ? 261 ASP E CG  1 
ATOM   14622 O OD1 . ASP E 1 261 ? 46.404  -3.895  54.037  1.00 26.92  ? 261 ASP E OD1 1 
ATOM   14623 O OD2 . ASP E 1 261 ? 45.838  -5.899  53.396  1.00 28.45  ? 261 ASP E OD2 1 
ATOM   14624 N N   . GLY E 1 262 ? 48.697  -2.512  52.414  1.00 29.03  ? 262 GLY E N   1 
ATOM   14625 C CA  . GLY E 1 262 ? 48.524  -1.101  52.069  1.00 28.75  ? 262 GLY E CA  1 
ATOM   14626 C C   . GLY E 1 262 ? 47.325  -0.410  52.709  1.00 30.44  ? 262 GLY E C   1 
ATOM   14627 O O   . GLY E 1 262 ? 47.236  0.823   52.643  1.00 30.25  ? 262 GLY E O   1 
ATOM   14628 N N   . ASP E 1 263 ? 46.414  -1.163  53.330  1.00 32.13  ? 263 ASP E N   1 
ATOM   14629 C CA  . ASP E 1 263 ? 45.179  -0.614  53.882  1.00 27.97  ? 263 ASP E CA  1 
ATOM   14630 C C   . ASP E 1 263 ? 45.163  -0.540  55.397  1.00 26.88  ? 263 ASP E C   1 
ATOM   14631 O O   . ASP E 1 263 ? 44.539  0.354   55.962  1.00 28.05  ? 263 ASP E O   1 
ATOM   14632 C CB  . ASP E 1 263 ? 43.981  -1.468  53.450  1.00 26.61  ? 263 ASP E CB  1 
ATOM   14633 C CG  . ASP E 1 263 ? 43.729  -1.426  51.957  1.00 35.10  ? 263 ASP E CG  1 
ATOM   14634 O OD1 . ASP E 1 263 ? 43.868  -0.337  51.347  1.00 37.16  ? 263 ASP E OD1 1 
ATOM   14635 O OD2 . ASP E 1 263 ? 43.359  -2.486  51.395  1.00 37.00  ? 263 ASP E OD2 1 
ATOM   14636 N N   . ARG E 1 264 ? 45.817  -1.472  56.061  1.00 24.62  ? 264 ARG E N   1 
ATOM   14637 C CA  . ARG E 1 264 ? 45.524  -1.707  57.456  1.00 28.16  ? 264 ARG E CA  1 
ATOM   14638 C C   . ARG E 1 264 ? 46.567  -2.664  57.989  1.00 26.86  ? 264 ARG E C   1 
ATOM   14639 O O   . ARG E 1 264 ? 47.143  -3.459  57.237  1.00 23.67  ? 264 ARG E O   1 
ATOM   14640 C CB  . ARG E 1 264 ? 44.129  -2.313  57.633  1.00 27.08  ? 264 ARG E CB  1 
ATOM   14641 C CG  . ARG E 1 264 ? 43.905  -3.509  56.690  1.00 28.28  ? 264 ARG E CG  1 
ATOM   14642 C CD  . ARG E 1 264 ? 43.553  -4.730  57.481  1.00 34.67  ? 264 ARG E CD  1 
ATOM   14643 N NE  . ARG E 1 264 ? 43.584  -5.992  56.741  1.00 36.22  ? 264 ARG E NE  1 
ATOM   14644 C CZ  . ARG E 1 264 ? 44.672  -6.704  56.475  1.00 31.33  ? 264 ARG E CZ  1 
ATOM   14645 N NH1 . ARG E 1 264 ? 45.886  -6.203  56.632  1.00 30.25  ? 264 ARG E NH1 1 
ATOM   14646 N NH2 . ARG E 1 264 ? 44.537  -7.966  56.069  1.00 29.06  ? 264 ARG E NH2 1 
ATOM   14647 N N   . ALA E 1 265 ? 46.807  -2.552  59.282  1.00 22.63  ? 265 ALA E N   1 
ATOM   14648 C CA  . ALA E 1 265 ? 47.529  -3.542  60.064  1.00 23.29  ? 265 ALA E CA  1 
ATOM   14649 C C   . ALA E 1 265 ? 46.461  -4.298  60.836  1.00 27.33  ? 265 ALA E C   1 
ATOM   14650 O O   . ALA E 1 265 ? 45.754  -3.715  61.671  1.00 18.31  ? 265 ALA E O   1 
ATOM   14651 C CB  . ALA E 1 265 ? 48.530  -2.878  61.005  1.00 19.38  ? 265 ALA E CB  1 
ATOM   14652 N N   . ARG E 1 266 ? 46.310  -5.574  60.535  1.00 23.47  ? 266 ARG E N   1 
ATOM   14653 C CA  . ARG E 1 266 ? 45.178  -6.335  61.039  1.00 26.33  ? 266 ARG E CA  1 
ATOM   14654 C C   . ARG E 1 266 ? 45.625  -7.207  62.203  1.00 24.07  ? 266 ARG E C   1 
ATOM   14655 O O   . ARG E 1 266 ? 46.485  -8.079  62.026  1.00 20.10  ? 266 ARG E O   1 
ATOM   14656 C CB  . ARG E 1 266 ? 44.559  -7.185  59.933  1.00 28.83  ? 266 ARG E CB  1 
ATOM   14657 C CG  . ARG E 1 266 ? 43.135  -7.587  60.285  1.00 37.44  ? 266 ARG E CG  1 
ATOM   14658 C CD  . ARG E 1 266 ? 43.006  -9.087  60.364  1.00 36.53  ? 266 ARG E CD  1 
ATOM   14659 N NE  . ARG E 1 266 ? 42.683  -9.644  59.052  1.00 47.84  ? 266 ARG E NE  1 
ATOM   14660 C CZ  . ARG E 1 266 ? 42.310  -10.896 58.819  1.00 42.23  ? 266 ARG E CZ  1 
ATOM   14661 N NH1 . ARG E 1 266 ? 42.214  -11.788 59.799  1.00 34.25  ? 266 ARG E NH1 1 
ATOM   14662 N NH2 . ARG E 1 266 ? 41.991  -11.251 57.575  1.00 39.12  ? 266 ARG E NH2 1 
ATOM   14663 N N   . PHE E 1 267 ? 45.064  -6.946  63.390  1.00 19.79  ? 267 PHE E N   1 
ATOM   14664 C CA  . PHE E 1 267 ? 45.233  -7.846  64.525  1.00 20.72  ? 267 PHE E CA  1 
ATOM   14665 C C   . PHE E 1 267 ? 44.780  -9.262  64.154  1.00 23.97  ? 267 PHE E C   1 
ATOM   14666 O O   . PHE E 1 267 ? 43.682  -9.456  63.627  1.00 22.51  ? 267 PHE E O   1 
ATOM   14667 C CB  . PHE E 1 267 ? 44.435  -7.316  65.726  1.00 22.18  ? 267 PHE E CB  1 
ATOM   14668 C CG  . PHE E 1 267 ? 44.591  -8.152  66.969  1.00 23.60  ? 267 PHE E CG  1 
ATOM   14669 C CD1 . PHE E 1 267 ? 43.794  -9.265  67.176  1.00 19.62  ? 267 PHE E CD1 1 
ATOM   14670 C CD2 . PHE E 1 267 ? 45.558  -7.833  67.922  1.00 26.00  ? 267 PHE E CD2 1 
ATOM   14671 C CE1 . PHE E 1 267 ? 43.935  -10.036 68.322  1.00 28.24  ? 267 PHE E CE1 1 
ATOM   14672 C CE2 . PHE E 1 267 ? 45.725  -8.611  69.063  1.00 26.96  ? 267 PHE E CE2 1 
ATOM   14673 C CZ  . PHE E 1 267 ? 44.914  -9.721  69.265  1.00 26.06  ? 267 PHE E CZ  1 
ATOM   14674 N N   . LEU E 1 268 ? 45.629  -10.262 64.414  1.00 23.95  ? 268 LEU E N   1 
ATOM   14675 C CA  . LEU E 1 268 ? 45.301  -11.636 64.043  1.00 21.25  ? 268 LEU E CA  1 
ATOM   14676 C C   . LEU E 1 268 ? 44.938  -12.501 65.236  1.00 23.22  ? 268 LEU E C   1 
ATOM   14677 O O   . LEU E 1 268 ? 43.866  -13.113 65.263  1.00 24.44  ? 268 LEU E O   1 
ATOM   14678 C CB  . LEU E 1 268 ? 46.459  -12.286 63.266  1.00 20.69  ? 268 LEU E CB  1 
ATOM   14679 C CG  . LEU E 1 268 ? 46.755  -11.798 61.831  1.00 22.46  ? 268 LEU E CG  1 
ATOM   14680 C CD1 . LEU E 1 268 ? 47.758  -12.721 61.160  1.00 16.15  ? 268 LEU E CD1 1 
ATOM   14681 C CD2 . LEU E 1 268 ? 45.479  -11.648 60.961  1.00 21.83  ? 268 LEU E CD2 1 
ATOM   14682 N N   . HIS E 1 269 ? 45.795  -12.545 66.242  1.00 23.23  ? 269 HIS E N   1 
ATOM   14683 C CA  . HIS E 1 269 ? 45.557  -13.359 67.420  1.00 25.67  ? 269 HIS E CA  1 
ATOM   14684 C C   . HIS E 1 269 ? 46.533  -12.898 68.483  1.00 25.45  ? 269 HIS E C   1 
ATOM   14685 O O   . HIS E 1 269 ? 47.572  -12.307 68.174  1.00 25.18  ? 269 HIS E O   1 
ATOM   14686 C CB  . HIS E 1 269 ? 45.753  -14.864 67.136  1.00 23.00  ? 269 HIS E CB  1 
ATOM   14687 C CG  . HIS E 1 269 ? 47.174  -15.243 66.832  1.00 21.60  ? 269 HIS E CG  1 
ATOM   14688 N ND1 . HIS E 1 269 ? 48.095  -15.554 67.817  1.00 22.34  ? 269 HIS E ND1 1 
ATOM   14689 C CD2 . HIS E 1 269 ? 47.835  -15.348 65.654  1.00 19.90  ? 269 HIS E CD2 1 
ATOM   14690 C CE1 . HIS E 1 269 ? 49.261  -15.827 67.259  1.00 24.61  ? 269 HIS E CE1 1 
ATOM   14691 N NE2 . HIS E 1 269 ? 49.133  -15.704 65.945  1.00 23.29  ? 269 HIS E NE2 1 
ATOM   14692 N N   . SER E 1 270 ? 46.201  -13.195 69.730  1.00 21.22  ? 270 SER E N   1 
ATOM   14693 C CA  . SER E 1 270 ? 47.157  -13.163 70.825  1.00 27.47  ? 270 SER E CA  1 
ATOM   14694 C C   . SER E 1 270 ? 47.402  -14.591 71.296  1.00 28.00  ? 270 SER E C   1 
ATOM   14695 O O   . SER E 1 270 ? 46.466  -15.395 71.366  1.00 30.19  ? 270 SER E O   1 
ATOM   14696 C CB  . SER E 1 270 ? 46.633  -12.319 71.988  1.00 23.28  ? 270 SER E CB  1 
ATOM   14697 O OG  . SER E 1 270 ? 45.546  -12.965 72.636  1.00 27.42  ? 270 SER E OG  1 
ATOM   14698 N N   . SER E 1 271 ? 48.652  -14.900 71.636  1.00 29.50  ? 271 SER E N   1 
ATOM   14699 C CA  . SER E 1 271 ? 49.006  -16.216 72.147  1.00 32.54  ? 271 SER E CA  1 
ATOM   14700 C C   . SER E 1 271 ? 49.929  -16.084 73.363  1.00 32.92  ? 271 SER E C   1 
ATOM   14701 O O   . SER E 1 271 ? 50.333  -14.987 73.769  1.00 31.95  ? 271 SER E O   1 
ATOM   14702 C CB  . SER E 1 271 ? 49.626  -17.074 71.034  1.00 33.42  ? 271 SER E CB  1 
ATOM   14703 O OG  . SER E 1 271 ? 48.654  -17.355 70.030  1.00 28.63  ? 271 SER E OG  1 
ATOM   14704 N N   . ILE E 1 272 ? 50.240  -17.222 73.973  1.00 32.46  ? 272 ILE E N   1 
ATOM   14705 C CA  . ILE E 1 272 ? 51.073  -17.266 75.168  1.00 34.44  ? 272 ILE E CA  1 
ATOM   14706 C C   . ILE E 1 272 ? 52.187  -18.258 74.914  1.00 35.66  ? 272 ILE E C   1 
ATOM   14707 O O   . ILE E 1 272 ? 51.916  -19.434 74.664  1.00 37.97  ? 272 ILE E O   1 
ATOM   14708 C CB  . ILE E 1 272 ? 50.289  -17.684 76.424  1.00 32.64  ? 272 ILE E CB  1 
ATOM   14709 C CG1 . ILE E 1 272 ? 49.021  -16.870 76.606  1.00 34.18  ? 272 ILE E CG1 1 
ATOM   14710 C CG2 . ILE E 1 272 ? 51.162  -17.549 77.645  1.00 37.52  ? 272 ILE E CG2 1 
ATOM   14711 C CD1 . ILE E 1 272 ? 48.163  -17.386 77.769  1.00 35.36  ? 272 ILE E CD1 1 
ATOM   14712 N N   . LEU E 1 273 ? 53.430  -17.800 75.010  1.00 36.70  ? 273 LEU E N   1 
ATOM   14713 C CA  . LEU E 1 273 ? 54.562  -18.716 74.985  1.00 44.05  ? 273 LEU E CA  1 
ATOM   14714 C C   . LEU E 1 273 ? 54.642  -19.463 76.312  1.00 39.79  ? 273 LEU E C   1 
ATOM   14715 O O   . LEU E 1 273 ? 54.591  -18.853 77.383  1.00 41.61  ? 273 LEU E O   1 
ATOM   14716 C CB  . LEU E 1 273 ? 55.849  -17.941 74.711  1.00 48.24  ? 273 LEU E CB  1 
ATOM   14717 C CG  . LEU E 1 273 ? 56.114  -17.608 73.234  1.00 54.22  ? 273 LEU E CG  1 
ATOM   14718 C CD1 . LEU E 1 273 ? 56.951  -16.344 73.071  1.00 56.49  ? 273 LEU E CD1 1 
ATOM   14719 C CD2 . LEU E 1 273 ? 56.801  -18.762 72.553  1.00 56.58  ? 273 LEU E CD2 1 
ATOM   14720 N N   . LYS E 1 274 ? 54.740  -20.787 76.248  1.00 45.90  ? 274 LYS E N   1 
ATOM   14721 C CA  . LYS E 1 274 ? 54.683  -21.630 77.435  1.00 43.23  ? 274 LYS E CA  1 
ATOM   14722 C C   . LYS E 1 274 ? 56.006  -22.353 77.609  1.00 48.17  ? 274 LYS E C   1 
ATOM   14723 O O   . LYS E 1 274 ? 56.593  -22.826 76.632  1.00 52.35  ? 274 LYS E O   1 
ATOM   14724 C CB  . LYS E 1 274 ? 53.537  -22.632 77.337  1.00 45.79  ? 274 LYS E CB  1 
ATOM   14725 C CG  . LYS E 1 274 ? 52.208  -21.994 76.940  1.00 41.02  ? 274 LYS E CG  1 
ATOM   14726 C CD  . LYS E 1 274 ? 51.643  -21.128 78.064  1.00 39.00  ? 274 LYS E CD  1 
ATOM   14727 C CE  . LYS E 1 274 ? 51.651  -21.835 79.408  1.00 40.49  ? 274 LYS E CE  1 
ATOM   14728 N NZ  . LYS E 1 274 ? 50.408  -21.524 80.183  1.00 44.64  ? 274 LYS E NZ  1 
ATOM   14729 N N   . TYR E 1 275 ? 56.462  -22.451 78.859  1.00 52.08  ? 275 TYR E N   1 
ATOM   14730 C CA  . TYR E 1 275 ? 57.821  -22.877 79.181  1.00 56.74  ? 275 TYR E CA  1 
ATOM   14731 C C   . TYR E 1 275 ? 57.821  -24.042 80.169  1.00 55.43  ? 275 TYR E C   1 
ATOM   14732 O O   . TYR E 1 275 ? 56.776  -24.481 80.663  1.00 54.35  ? 275 TYR E O   1 
ATOM   14733 C CB  . TYR E 1 275 ? 58.628  -21.714 79.765  1.00 57.50  ? 275 TYR E CB  1 
ATOM   14734 C CG  . TYR E 1 275 ? 58.976  -20.655 78.758  1.00 54.44  ? 275 TYR E CG  1 
ATOM   14735 C CD1 . TYR E 1 275 ? 60.075  -20.799 77.923  1.00 55.41  ? 275 TYR E CD1 1 
ATOM   14736 C CD2 . TYR E 1 275 ? 58.203  -19.512 78.637  1.00 55.38  ? 275 TYR E CD2 1 
ATOM   14737 C CE1 . TYR E 1 275 ? 60.400  -19.832 77.000  1.00 55.66  ? 275 TYR E CE1 1 
ATOM   14738 C CE2 . TYR E 1 275 ? 58.515  -18.541 77.715  1.00 56.90  ? 275 TYR E CE2 1 
ATOM   14739 C CZ  . TYR E 1 275 ? 59.617  -18.704 76.902  1.00 55.11  ? 275 TYR E CZ  1 
ATOM   14740 O OH  . TYR E 1 275 ? 59.924  -17.731 75.988  1.00 50.83  ? 275 TYR E OH  1 
ATOM   14741 N N   . GLU E 1 276 ? 59.030  -24.522 80.459  1.00 59.92  ? 276 GLU E N   1 
ATOM   14742 C CA  . GLU E 1 276 ? 59.281  -25.533 81.491  1.00 63.47  ? 276 GLU E CA  1 
ATOM   14743 C C   . GLU E 1 276 ? 58.567  -26.840 81.174  1.00 61.94  ? 276 GLU E C   1 
ATOM   14744 O O   . GLU E 1 276 ? 57.833  -27.371 82.009  1.00 63.86  ? 276 GLU E O   1 
ATOM   14745 C CB  . GLU E 1 276 ? 58.855  -25.020 82.879  1.00 53.72  ? 276 GLU E CB  1 
ATOM   14746 C CG  . GLU E 1 276 ? 59.629  -25.631 84.052  1.00 65.33  ? 276 GLU E CG  1 
ATOM   14747 C CD  . GLU E 1 276 ? 58.765  -25.853 85.295  1.00 66.31  ? 276 GLU E CD  1 
ATOM   14748 O OE1 . GLU E 1 276 ? 57.914  -24.985 85.591  1.00 68.64  ? 276 GLU E OE1 1 
ATOM   14749 O OE2 . GLU E 1 276 ? 58.950  -26.885 85.984  1.00 55.76  ? 276 GLU E OE2 1 
ATOM   14750 N N   . SER E 1 285 ? 67.881  -23.721 82.112  1.00 62.63  ? 285 SER E N   1 
ATOM   14751 C CA  . SER E 1 285 ? 66.764  -22.782 82.180  1.00 71.07  ? 285 SER E CA  1 
ATOM   14752 C C   . SER E 1 285 ? 65.591  -23.300 81.341  1.00 72.20  ? 285 SER E C   1 
ATOM   14753 O O   . SER E 1 285 ? 65.674  -24.383 80.751  1.00 73.86  ? 285 SER E O   1 
ATOM   14754 C CB  . SER E 1 285 ? 67.196  -21.382 81.719  1.00 68.10  ? 285 SER E CB  1 
ATOM   14755 O OG  . SER E 1 285 ? 67.856  -20.669 82.760  1.00 63.10  ? 285 SER E OG  1 
ATOM   14756 N N   . ALA E 1 286 ? 64.511  -22.519 81.282  1.00 71.49  ? 286 ALA E N   1 
ATOM   14757 C CA  . ALA E 1 286 ? 63.217  -23.019 80.824  1.00 66.56  ? 286 ALA E CA  1 
ATOM   14758 C C   . ALA E 1 286 ? 63.211  -23.230 79.314  1.00 65.84  ? 286 ALA E C   1 
ATOM   14759 O O   . ALA E 1 286 ? 63.396  -22.281 78.547  1.00 65.64  ? 286 ALA E O   1 
ATOM   14760 C CB  . ALA E 1 286 ? 62.110  -22.050 81.229  1.00 63.08  ? 286 ALA E CB  1 
ATOM   14761 N N   . LYS E 1 287 ? 62.973  -24.465 78.884  1.00 70.78  ? 287 LYS E N   1 
ATOM   14762 C CA  . LYS E 1 287 ? 62.868  -24.755 77.462  1.00 63.75  ? 287 LYS E CA  1 
ATOM   14763 C C   . LYS E 1 287 ? 61.437  -24.527 76.979  1.00 61.70  ? 287 LYS E C   1 
ATOM   14764 O O   . LYS E 1 287 ? 60.469  -24.672 77.736  1.00 57.29  ? 287 LYS E O   1 
ATOM   14765 C CB  . LYS E 1 287 ? 63.323  -26.186 77.161  1.00 60.66  ? 287 LYS E CB  1 
ATOM   14766 C CG  . LYS E 1 287 ? 62.366  -27.275 77.608  1.00 67.60  ? 287 LYS E CG  1 
ATOM   14767 C CD  . LYS E 1 287 ? 62.593  -28.564 76.815  1.00 70.31  ? 287 LYS E CD  1 
ATOM   14768 C CE  . LYS E 1 287 ? 61.316  -29.401 76.737  1.00 68.56  ? 287 LYS E CE  1 
ATOM   14769 N NZ  . LYS E 1 287 ? 61.557  -30.858 76.530  1.00 69.14  ? 287 LYS E NZ  1 
ATOM   14770 N N   . TRP E 1 288 ? 61.321  -24.140 75.707  1.00 56.72  ? 288 TRP E N   1 
ATOM   14771 C CA  . TRP E 1 288 ? 60.041  -23.803 75.096  1.00 55.00  ? 288 TRP E CA  1 
ATOM   14772 C C   . TRP E 1 288 ? 59.298  -25.065 74.675  1.00 55.45  ? 288 TRP E C   1 
ATOM   14773 O O   . TRP E 1 288 ? 59.835  -25.890 73.928  1.00 58.87  ? 288 TRP E O   1 
ATOM   14774 C CB  . TRP E 1 288 ? 60.266  -22.902 73.883  1.00 54.66  ? 288 TRP E CB  1 
ATOM   14775 C CG  . TRP E 1 288 ? 59.007  -22.575 73.158  1.00 52.45  ? 288 TRP E CG  1 
ATOM   14776 C CD1 . TRP E 1 288 ? 57.861  -22.067 73.698  1.00 54.68  ? 288 TRP E CD1 1 
ATOM   14777 C CD2 . TRP E 1 288 ? 58.755  -22.729 71.755  1.00 48.10  ? 288 TRP E CD2 1 
ATOM   14778 N NE1 . TRP E 1 288 ? 56.907  -21.901 72.719  1.00 50.80  ? 288 TRP E NE1 1 
ATOM   14779 C CE2 . TRP E 1 288 ? 57.434  -22.297 71.517  1.00 51.83  ? 288 TRP E CE2 1 
ATOM   14780 C CE3 . TRP E 1 288 ? 59.518  -23.181 70.676  1.00 48.13  ? 288 TRP E CE3 1 
ATOM   14781 C CZ2 . TRP E 1 288 ? 56.861  -22.314 70.248  1.00 45.03  ? 288 TRP E CZ2 1 
ATOM   14782 C CZ3 . TRP E 1 288 ? 58.943  -23.197 69.418  1.00 44.86  ? 288 TRP E CZ3 1 
ATOM   14783 C CH2 . TRP E 1 288 ? 57.632  -22.765 69.215  1.00 41.24  ? 288 TRP E CH2 1 
ATOM   14784 N N   . ILE E 1 289 ? 58.055  -25.208 75.131  1.00 51.94  ? 289 ILE E N   1 
ATOM   14785 C CA  . ILE E 1 289 ? 57.311  -26.449 74.949  1.00 48.52  ? 289 ILE E CA  1 
ATOM   14786 C C   . ILE E 1 289 ? 56.021  -26.271 74.162  1.00 50.29  ? 289 ILE E C   1 
ATOM   14787 O O   . ILE E 1 289 ? 55.410  -27.282 73.766  1.00 49.77  ? 289 ILE E O   1 
ATOM   14788 C CB  . ILE E 1 289 ? 57.011  -27.127 76.302  1.00 52.26  ? 289 ILE E CB  1 
ATOM   14789 C CG1 . ILE E 1 289 ? 56.491  -26.110 77.319  1.00 50.02  ? 289 ILE E CG1 1 
ATOM   14790 C CG2 . ILE E 1 289 ? 58.250  -27.804 76.826  1.00 57.04  ? 289 ILE E CG2 1 
ATOM   14791 C CD1 . ILE E 1 289 ? 55.403  -26.676 78.229  1.00 51.58  ? 289 ILE E CD1 1 
ATOM   14792 N N   . GLY E 1 290 ? 55.584  -25.046 73.909  1.00 49.72  ? 290 GLY E N   1 
ATOM   14793 C CA  . GLY E 1 290 ? 54.424  -24.833 73.068  1.00 43.92  ? 290 GLY E CA  1 
ATOM   14794 C C   . GLY E 1 290 ? 53.786  -23.487 73.351  1.00 39.74  ? 290 GLY E C   1 
ATOM   14795 O O   . GLY E 1 290 ? 54.368  -22.621 74.003  1.00 34.72  ? 290 GLY E O   1 
ATOM   14796 N N   . LEU E 1 291 ? 52.569  -23.328 72.840  1.00 38.61  ? 291 LEU E N   1 
ATOM   14797 C CA  . LEU E 1 291 ? 51.844  -22.115 73.166  1.00 34.94  ? 291 LEU E CA  1 
ATOM   14798 C C   . LEU E 1 291 ? 50.361  -22.388 73.346  1.00 36.50  ? 291 LEU E C   1 
ATOM   14799 O O   . LEU E 1 291 ? 49.799  -23.319 72.767  1.00 34.79  ? 291 LEU E O   1 
ATOM   14800 C CB  . LEU E 1 291 ? 52.088  -21.032 72.127  1.00 33.16  ? 291 LEU E CB  1 
ATOM   14801 C CG  . LEU E 1 291 ? 51.827  -21.213 70.661  1.00 34.81  ? 291 LEU E CG  1 
ATOM   14802 C CD1 . LEU E 1 291 ? 50.351  -20.980 70.442  1.00 34.66  ? 291 LEU E CD1 1 
ATOM   14803 C CD2 . LEU E 1 291 ? 52.716  -20.207 69.868  1.00 27.31  ? 291 LEU E CD2 1 
ATOM   14804 N N   . ASP E 1 292 ? 49.745  -21.563 74.180  1.00 35.31  ? 292 ASP E N   1 
ATOM   14805 C CA  . ASP E 1 292 ? 48.316  -21.579 74.411  1.00 36.15  ? 292 ASP E CA  1 
ATOM   14806 C C   . ASP E 1 292 ? 47.707  -20.381 73.697  1.00 38.02  ? 292 ASP E C   1 
ATOM   14807 O O   . ASP E 1 292 ? 48.365  -19.349 73.519  1.00 36.30  ? 292 ASP E O   1 
ATOM   14808 C CB  . ASP E 1 292 ? 48.004  -21.530 75.913  1.00 38.62  ? 292 ASP E CB  1 
ATOM   14809 C CG  . ASP E 1 292 ? 48.699  -22.645 76.713  1.00 40.84  ? 292 ASP E CG  1 
ATOM   14810 O OD1 . ASP E 1 292 ? 49.269  -23.578 76.103  1.00 35.54  ? 292 ASP E OD1 1 
ATOM   14811 O OD2 . ASP E 1 292 ? 48.655  -22.589 77.967  1.00 43.87  ? 292 ASP E OD2 1 
ATOM   14812 N N   . SER E 1 293 ? 46.449  -20.518 73.261  1.00 35.59  ? 293 SER E N   1 
ATOM   14813 C CA  . SER E 1 293 ? 45.884  -19.344 72.606  1.00 39.24  ? 293 SER E CA  1 
ATOM   14814 C C   . SER E 1 293 ? 44.567  -18.885 73.218  1.00 41.10  ? 293 SER E C   1 
ATOM   14815 O O   . SER E 1 293 ? 44.074  -19.514 74.158  1.00 49.67  ? 293 SER E O   1 
ATOM   14816 C CB  . SER E 1 293 ? 45.698  -19.571 71.122  1.00 33.90  ? 293 SER E CB  1 
ATOM   14817 O OG  . SER E 1 293 ? 45.705  -18.316 70.467  1.00 36.39  ? 293 SER E OG  1 
ATOM   14818 N N   . PRO E 1 294 ? 43.888  -17.917 72.604  1.00 40.33  ? 294 PRO E N   1 
ATOM   14819 C CA  . PRO E 1 294 ? 43.636  -16.650 73.292  1.00 37.71  ? 294 PRO E CA  1 
ATOM   14820 C C   . PRO E 1 294 ? 44.560  -16.446 74.483  1.00 36.31  ? 294 PRO E C   1 
ATOM   14821 O O   . PRO E 1 294 ? 44.509  -17.187 75.470  1.00 35.47  ? 294 PRO E O   1 
ATOM   14822 C CB  . PRO E 1 294 ? 42.169  -16.769 73.711  1.00 40.91  ? 294 PRO E CB  1 
ATOM   14823 C CG  . PRO E 1 294 ? 41.563  -17.504 72.604  1.00 41.04  ? 294 PRO E CG  1 
ATOM   14824 C CD  . PRO E 1 294 ? 42.639  -18.410 71.994  1.00 44.38  ? 294 PRO E CD  1 
ATOM   14825 N N   . SER E 1 295 ? 45.416  -15.436 74.398  1.00 35.17  ? 295 SER E N   1 
ATOM   14826 C CA  . SER E 1 295 ? 46.152  -15.024 75.580  1.00 36.40  ? 295 SER E CA  1 
ATOM   14827 C C   . SER E 1 295 ? 45.198  -14.399 76.591  1.00 31.67  ? 295 SER E C   1 
ATOM   14828 O O   . SER E 1 295 ? 44.042  -14.110 76.291  1.00 35.22  ? 295 SER E O   1 
ATOM   14829 C CB  . SER E 1 295 ? 47.220  -14.001 75.229  1.00 27.06  ? 295 SER E CB  1 
ATOM   14830 O OG  . SER E 1 295 ? 46.685  -12.709 75.419  1.00 23.17  ? 295 SER E OG  1 
ATOM   14831 N N   . ARG E 1 296 ? 45.709  -14.143 77.794  1.00 37.65  ? 296 ARG E N   1 
ATOM   14832 C CA  . ARG E 1 296 ? 44.931  -13.487 78.836  1.00 37.84  ? 296 ARG E CA  1 
ATOM   14833 C C   . ARG E 1 296 ? 45.196  -11.989 78.890  1.00 35.55  ? 296 ARG E C   1 
ATOM   14834 O O   . ARG E 1 296 ? 45.004  -11.366 79.940  1.00 40.06  ? 296 ARG E O   1 
ATOM   14835 C CB  . ARG E 1 296 ? 45.218  -14.124 80.197  1.00 38.49  ? 296 ARG E CB  1 
ATOM   14836 C CG  . ARG E 1 296 ? 44.144  -15.086 80.670  1.00 52.55  ? 296 ARG E CG  1 
ATOM   14837 C CD  . ARG E 1 296 ? 44.725  -16.250 81.467  1.00 58.31  ? 296 ARG E CD  1 
ATOM   14838 N NE  . ARG E 1 296 ? 43.732  -17.300 81.674  1.00 73.65  ? 296 ARG E NE  1 
ATOM   14839 C CZ  . ARG E 1 296 ? 44.014  -18.538 82.059  1.00 76.75  ? 296 ARG E CZ  1 
ATOM   14840 N NH1 . ARG E 1 296 ? 45.254  -18.912 82.335  1.00 73.00  ? 296 ARG E NH1 1 
ATOM   14841 N NH2 . ARG E 1 296 ? 43.027  -19.426 82.166  1.00 73.30  ? 296 ARG E NH2 1 
ATOM   14842 N N   . SER E 1 297 ? 45.609  -11.387 77.774  1.00 31.47  ? 297 SER E N   1 
ATOM   14843 C CA  . SER E 1 297 ? 46.127  -10.026 77.835  1.00 29.77  ? 297 SER E CA  1 
ATOM   14844 C C   . SER E 1 297 ? 45.587  -9.089  76.753  1.00 36.66  ? 297 SER E C   1 
ATOM   14845 O O   . SER E 1 297 ? 46.251  -8.093  76.428  1.00 32.91  ? 297 SER E O   1 
ATOM   14846 C CB  . SER E 1 297 ? 47.648  -10.059 77.754  1.00 28.85  ? 297 SER E CB  1 
ATOM   14847 O OG  . SER E 1 297 ? 48.159  -11.013 78.647  1.00 29.48  ? 297 SER E OG  1 
ATOM   14848 N N   . GLU E 1 298 ? 44.404  -9.357  76.195  1.00 33.30  ? 298 GLU E N   1 
ATOM   14849 C CA  . GLU E 1 298 ? 43.802  -8.452  75.216  1.00 33.27  ? 298 GLU E CA  1 
ATOM   14850 C C   . GLU E 1 298 ? 42.929  -7.430  75.950  1.00 36.09  ? 298 GLU E C   1 
ATOM   14851 O O   . GLU E 1 298 ? 41.703  -7.537  76.006  1.00 40.68  ? 298 GLU E O   1 
ATOM   14852 C CB  . GLU E 1 298 ? 42.998  -9.234  74.181  1.00 30.06  ? 298 GLU E CB  1 
ATOM   14853 C CG  . GLU E 1 298 ? 43.827  -9.946  73.109  1.00 31.08  ? 298 GLU E CG  1 
ATOM   14854 C CD  . GLU E 1 298 ? 42.973  -10.883 72.243  1.00 35.34  ? 298 GLU E CD  1 
ATOM   14855 O OE1 . GLU E 1 298 ? 41.863  -10.469 71.848  1.00 36.48  ? 298 GLU E OE1 1 
ATOM   14856 O OE2 . GLU E 1 298 ? 43.401  -12.027 71.956  1.00 31.19  ? 298 GLU E OE2 1 
ATOM   14857 N N   . PHE E 1 299 ? 43.578  -6.415  76.526  1.00 34.92  ? 299 PHE E N   1 
ATOM   14858 C CA  . PHE E 1 299 ? 42.864  -5.266  77.079  1.00 33.75  ? 299 PHE E CA  1 
ATOM   14859 C C   . PHE E 1 299 ? 43.567  -3.990  76.655  1.00 34.21  ? 299 PHE E C   1 
ATOM   14860 O O   . PHE E 1 299 ? 44.703  -4.013  76.175  1.00 33.94  ? 299 PHE E O   1 
ATOM   14861 C CB  . PHE E 1 299 ? 42.739  -5.301  78.611  1.00 35.64  ? 299 PHE E CB  1 
ATOM   14862 C CG  . PHE E 1 299 ? 43.896  -5.957  79.322  1.00 35.50  ? 299 PHE E CG  1 
ATOM   14863 C CD1 . PHE E 1 299 ? 43.797  -7.264  79.754  1.00 38.60  ? 299 PHE E CD1 1 
ATOM   14864 C CD2 . PHE E 1 299 ? 45.042  -5.244  79.622  1.00 39.21  ? 299 PHE E CD2 1 
ATOM   14865 C CE1 . PHE E 1 299 ? 44.840  -7.874  80.431  1.00 40.94  ? 299 PHE E CE1 1 
ATOM   14866 C CE2 . PHE E 1 299 ? 46.097  -5.846  80.306  1.00 40.49  ? 299 PHE E CE2 1 
ATOM   14867 C CZ  . PHE E 1 299 ? 45.996  -7.161  80.708  1.00 40.87  ? 299 PHE E CZ  1 
ATOM   14868 N N   . GLU E 1 300 ? 42.885  -2.861  76.869  1.00 34.34  ? 300 GLU E N   1 
ATOM   14869 C CA  . GLU E 1 300 ? 43.336  -1.611  76.268  1.00 37.99  ? 300 GLU E CA  1 
ATOM   14870 C C   . GLU E 1 300 ? 44.797  -1.314  76.607  1.00 32.34  ? 300 GLU E C   1 
ATOM   14871 O O   . GLU E 1 300 ? 45.552  -0.853  75.750  1.00 28.96  ? 300 GLU E O   1 
ATOM   14872 C CB  . GLU E 1 300 ? 42.422  -0.448  76.690  1.00 36.22  ? 300 GLU E CB  1 
ATOM   14873 C CG  . GLU E 1 300 ? 42.805  0.876   76.022  1.00 41.81  ? 300 GLU E CG  1 
ATOM   14874 C CD  . GLU E 1 300 ? 42.268  2.111   76.734  1.00 58.01  ? 300 GLU E CD  1 
ATOM   14875 O OE1 . GLU E 1 300 ? 42.012  2.057   77.961  1.00 59.62  ? 300 GLU E OE1 1 
ATOM   14876 O OE2 . GLU E 1 300 ? 42.103  3.151   76.056  1.00 61.58  ? 300 GLU E OE2 1 
ATOM   14877 N N   . ALA E 1 301 ? 45.226  -1.612  77.836  1.00 35.28  ? 301 ALA E N   1 
ATOM   14878 C CA  . ALA E 1 301 ? 46.576  -1.252  78.257  1.00 31.75  ? 301 ALA E CA  1 
ATOM   14879 C C   . ALA E 1 301 ? 47.656  -1.998  77.483  1.00 29.64  ? 301 ALA E C   1 
ATOM   14880 O O   . ALA E 1 301 ? 48.818  -1.590  77.517  1.00 36.29  ? 301 ALA E O   1 
ATOM   14881 C CB  . ALA E 1 301 ? 46.751  -1.505  79.758  1.00 38.91  ? 301 ALA E CB  1 
ATOM   14882 N N   . THR E 1 302 ? 47.315  -3.079  76.798  1.00 31.03  ? 302 THR E N   1 
ATOM   14883 C CA  . THR E 1 302 ? 48.257  -3.774  75.921  1.00 32.04  ? 302 THR E CA  1 
ATOM   14884 C C   . THR E 1 302 ? 47.944  -3.603  74.444  1.00 30.85  ? 302 THR E C   1 
ATOM   14885 O O   . THR E 1 302 ? 48.867  -3.454  73.640  1.00 32.17  ? 302 THR E O   1 
ATOM   14886 C CB  . THR E 1 302 ? 48.286  -5.274  76.236  1.00 29.60  ? 302 THR E CB  1 
ATOM   14887 O OG1 . THR E 1 302 ? 46.979  -5.828  76.032  1.00 30.05  ? 302 THR E OG1 1 
ATOM   14888 C CG2 . THR E 1 302 ? 48.739  -5.514  77.679  1.00 29.84  ? 302 THR E CG2 1 
ATOM   14889 N N   . LEU E 1 303 ? 46.662  -3.630  74.063  1.00 30.51  ? 303 LEU E N   1 
ATOM   14890 C CA  . LEU E 1 303 ? 46.313  -3.583  72.648  1.00 31.34  ? 303 LEU E CA  1 
ATOM   14891 C C   . LEU E 1 303 ? 46.606  -2.210  72.068  1.00 27.14  ? 303 LEU E C   1 
ATOM   14892 O O   . LEU E 1 303 ? 47.183  -2.098  70.982  1.00 23.64  ? 303 LEU E O   1 
ATOM   14893 C CB  . LEU E 1 303 ? 44.836  -3.945  72.442  1.00 31.00  ? 303 LEU E CB  1 
ATOM   14894 C CG  . LEU E 1 303 ? 44.407  -5.407  72.645  1.00 32.18  ? 303 LEU E CG  1 
ATOM   14895 C CD1 . LEU E 1 303 ? 42.897  -5.517  72.842  1.00 25.10  ? 303 LEU E CD1 1 
ATOM   14896 C CD2 . LEU E 1 303 ? 44.858  -6.282  71.487  1.00 31.40  ? 303 LEU E CD2 1 
ATOM   14897 N N   . LYS E 1 304 ? 46.206  -1.153  72.784  1.00 29.16  ? 304 LYS E N   1 
ATOM   14898 C CA  . LYS E 1 304 ? 46.295  0.202   72.244  1.00 28.18  ? 304 LYS E CA  1 
ATOM   14899 C C   . LYS E 1 304 ? 47.742  0.635   72.032  1.00 27.76  ? 304 LYS E C   1 
ATOM   14900 O O   . LYS E 1 304 ? 48.056  1.120   70.931  1.00 26.42  ? 304 LYS E O   1 
ATOM   14901 C CB  . LYS E 1 304 ? 45.480  1.157   73.142  1.00 27.29  ? 304 LYS E CB  1 
ATOM   14902 C CG  . LYS E 1 304 ? 45.588  2.630   72.828  1.00 34.58  ? 304 LYS E CG  1 
ATOM   14903 C CD  . LYS E 1 304 ? 46.518  3.367   73.833  1.00 41.97  ? 304 LYS E CD  1 
ATOM   14904 C CE  . LYS E 1 304 ? 45.780  3.861   75.086  1.00 46.65  ? 304 LYS E CE  1 
ATOM   14905 N NZ  . LYS E 1 304 ? 46.574  3.666   76.344  1.00 43.98  ? 304 LYS E NZ  1 
ATOM   14906 N N   . PRO E 1 305 ? 48.675  0.463   72.986  1.00 28.45  ? 305 PRO E N   1 
ATOM   14907 C CA  . PRO E 1 305 ? 50.085  0.757   72.650  1.00 25.09  ? 305 PRO E CA  1 
ATOM   14908 C C   . PRO E 1 305 ? 50.655  -0.148  71.563  1.00 26.71  ? 305 PRO E C   1 
ATOM   14909 O O   . PRO E 1 305 ? 51.368  0.338   70.679  1.00 26.00  ? 305 PRO E O   1 
ATOM   14910 C CB  . PRO E 1 305 ? 50.833  0.582   73.987  1.00 27.05  ? 305 PRO E CB  1 
ATOM   14911 C CG  . PRO E 1 305 ? 49.800  0.545   75.048  1.00 30.71  ? 305 PRO E CG  1 
ATOM   14912 C CD  . PRO E 1 305 ? 48.461  0.264   74.432  1.00 28.15  ? 305 PRO E CD  1 
ATOM   14913 N N   . ALA E 1 306 ? 50.369  -1.451  71.594  1.00 24.72  ? 306 ALA E N   1 
ATOM   14914 C CA  . ALA E 1 306 ? 50.881  -2.322  70.538  1.00 27.70  ? 306 ALA E CA  1 
ATOM   14915 C C   . ALA E 1 306 ? 50.366  -1.880  69.175  1.00 21.12  ? 306 ALA E C   1 
ATOM   14916 O O   . ALA E 1 306 ? 51.117  -1.882  68.199  1.00 19.98  ? 306 ALA E O   1 
ATOM   14917 C CB  . ALA E 1 306 ? 50.507  -3.789  70.810  1.00 21.70  ? 306 ALA E CB  1 
ATOM   14918 N N   . GLU E 1 307 ? 49.095  -1.470  69.099  1.00 17.17  ? 307 GLU E N   1 
ATOM   14919 C CA  . GLU E 1 307 ? 48.535  -1.020  67.824  1.00 26.76  ? 307 GLU E CA  1 
ATOM   14920 C C   . GLU E 1 307 ? 49.277  0.197   67.290  1.00 24.51  ? 307 GLU E C   1 
ATOM   14921 O O   . GLU E 1 307 ? 49.582  0.270   66.092  1.00 22.77  ? 307 GLU E O   1 
ATOM   14922 C CB  . GLU E 1 307 ? 47.036  -0.701  67.967  1.00 26.22  ? 307 GLU E CB  1 
ATOM   14923 C CG  . GLU E 1 307 ? 46.369  -0.209  66.656  1.00 21.77  ? 307 GLU E CG  1 
ATOM   14924 C CD  . GLU E 1 307 ? 44.945  0.375   66.865  1.00 36.36  ? 307 GLU E CD  1 
ATOM   14925 O OE1 . GLU E 1 307 ? 44.273  0.032   67.869  1.00 31.45  ? 307 GLU E OE1 1 
ATOM   14926 O OE2 . GLU E 1 307 ? 44.490  1.182   66.017  1.00 31.24  ? 307 GLU E OE2 1 
ATOM   14927 N N   . GLU E 1 308 ? 49.572  1.161   68.173  1.00 23.39  ? 308 GLU E N   1 
ATOM   14928 C CA  . GLU E 1 308 ? 50.288  2.368   67.780  1.00 24.43  ? 308 GLU E CA  1 
ATOM   14929 C C   . GLU E 1 308 ? 51.679  2.039   67.241  1.00 25.13  ? 308 GLU E C   1 
ATOM   14930 O O   . GLU E 1 308 ? 52.107  2.603   66.226  1.00 22.20  ? 308 GLU E O   1 
ATOM   14931 C CB  . GLU E 1 308 ? 50.371  3.319   68.974  1.00 26.33  ? 308 GLU E CB  1 
ATOM   14932 C CG  . GLU E 1 308 ? 50.806  4.718   68.611  1.00 35.11  ? 308 GLU E CG  1 
ATOM   14933 C CD  . GLU E 1 308 ? 51.340  5.522   69.797  1.00 35.75  ? 308 GLU E CD  1 
ATOM   14934 O OE1 . GLU E 1 308 ? 51.466  4.975   70.911  1.00 38.01  ? 308 GLU E OE1 1 
ATOM   14935 O OE2 . GLU E 1 308 ? 51.633  6.724   69.609  1.00 42.31  ? 308 GLU E OE2 1 
ATOM   14936 N N   . PHE E 1 309 ? 52.390  1.110   67.893  1.00 21.55  ? 309 PHE E N   1 
ATOM   14937 C CA  . PHE E 1 309 ? 53.713  0.716   67.416  1.00 23.15  ? 309 PHE E CA  1 
ATOM   14938 C C   . PHE E 1 309 ? 53.625  -0.065  66.098  1.00 26.77  ? 309 PHE E C   1 
ATOM   14939 O O   . PHE E 1 309 ? 54.372  0.214   65.148  1.00 21.91  ? 309 PHE E O   1 
ATOM   14940 C CB  . PHE E 1 309 ? 54.435  -0.104  68.491  1.00 26.35  ? 309 PHE E CB  1 
ATOM   14941 C CG  . PHE E 1 309 ? 55.871  -0.401  68.158  1.00 23.16  ? 309 PHE E CG  1 
ATOM   14942 C CD1 . PHE E 1 309 ? 56.201  -1.384  67.240  1.00 20.26  ? 309 PHE E CD1 1 
ATOM   14943 C CD2 . PHE E 1 309 ? 56.882  0.311   68.750  1.00 19.78  ? 309 PHE E CD2 1 
ATOM   14944 C CE1 . PHE E 1 309 ? 57.490  -1.635  66.924  1.00 19.81  ? 309 PHE E CE1 1 
ATOM   14945 C CE2 . PHE E 1 309 ? 58.182  0.044   68.440  1.00 24.02  ? 309 PHE E CE2 1 
ATOM   14946 C CZ  . PHE E 1 309 ? 58.484  -0.935  67.517  1.00 23.95  ? 309 PHE E CZ  1 
ATOM   14947 N N   . ILE E 1 310 ? 52.742  -1.068  66.023  1.00 21.91  ? 310 ILE E N   1 
ATOM   14948 C CA  . ILE E 1 310 ? 52.564  -1.763  64.749  1.00 22.30  ? 310 ILE E CA  1 
ATOM   14949 C C   . ILE E 1 310 ? 52.181  -0.775  63.634  1.00 22.04  ? 310 ILE E C   1 
ATOM   14950 O O   . ILE E 1 310 ? 52.667  -0.881  62.498  1.00 20.63  ? 310 ILE E O   1 
ATOM   14951 C CB  . ILE E 1 310 ? 51.538  -2.902  64.894  1.00 15.91  ? 310 ILE E CB  1 
ATOM   14952 C CG1 . ILE E 1 310 ? 51.985  -3.913  65.955  1.00 22.58  ? 310 ILE E CG1 1 
ATOM   14953 C CG2 . ILE E 1 310 ? 51.375  -3.645  63.585  1.00 17.48  ? 310 ILE E CG2 1 
ATOM   14954 C CD1 . ILE E 1 310 ? 53.318  -4.545  65.696  1.00 20.95  ? 310 ILE E CD1 1 
ATOM   14955 N N   . GLU E 1 311 ? 51.333  0.219   63.934  1.00 22.65  ? 311 GLU E N   1 
ATOM   14956 C CA  . GLU E 1 311 ? 50.949  1.161   62.874  1.00 22.01  ? 311 GLU E CA  1 
ATOM   14957 C C   . GLU E 1 311 ? 52.145  1.957   62.386  1.00 23.76  ? 311 GLU E C   1 
ATOM   14958 O O   . GLU E 1 311 ? 52.214  2.333   61.212  1.00 25.93  ? 311 GLU E O   1 
ATOM   14959 C CB  . GLU E 1 311 ? 49.856  2.112   63.356  1.00 24.76  ? 311 GLU E CB  1 
ATOM   14960 C CG  . GLU E 1 311 ? 49.166  2.908   62.232  1.00 24.73  ? 311 GLU E CG  1 
ATOM   14961 C CD  . GLU E 1 311 ? 48.536  2.021   61.154  1.00 28.33  ? 311 GLU E CD  1 
ATOM   14962 O OE1 . GLU E 1 311 ? 47.779  1.088   61.484  1.00 28.51  ? 311 GLU E OE1 1 
ATOM   14963 O OE2 . GLU E 1 311 ? 48.785  2.269   59.962  1.00 31.46  ? 311 GLU E OE2 1 
ATOM   14964 N N   . MET E 1 312 ? 53.097  2.208   63.273  1.00 18.94  ? 312 MET E N   1 
ATOM   14965 C CA  . MET E 1 312 ? 54.308  2.912   62.899  1.00 24.94  ? 312 MET E CA  1 
ATOM   14966 C C   . MET E 1 312 ? 55.194  2.031   62.034  1.00 28.54  ? 312 MET E C   1 
ATOM   14967 O O   . MET E 1 312 ? 55.850  2.519   61.102  1.00 21.95  ? 312 MET E O   1 
ATOM   14968 C CB  . MET E 1 312 ? 55.053  3.350   64.157  1.00 22.44  ? 312 MET E CB  1 
ATOM   14969 C CG  . MET E 1 312 ? 56.222  4.221   63.898  1.00 29.37  ? 312 MET E CG  1 
ATOM   14970 S SD  . MET E 1 312 ? 57.703  3.239   64.081  1.00 50.58  ? 312 MET E SD  1 
ATOM   14971 C CE  . MET E 1 312 ? 58.314  4.067   65.544  1.00 39.64  ? 312 MET E CE  1 
ATOM   14972 N N   . ILE E 1 313 ? 55.222  0.727   62.335  1.00 26.37  ? 313 ILE E N   1 
ATOM   14973 C CA  . ILE E 1 313 ? 55.947  -0.215  61.489  1.00 25.59  ? 313 ILE E CA  1 
ATOM   14974 C C   . ILE E 1 313 ? 55.342  -0.237  60.089  1.00 22.30  ? 313 ILE E C   1 
ATOM   14975 O O   . ILE E 1 313 ? 56.060  -0.239  59.081  1.00 23.80  ? 313 ILE E O   1 
ATOM   14976 C CB  . ILE E 1 313 ? 55.950  -1.608  62.147  1.00 22.01  ? 313 ILE E CB  1 
ATOM   14977 C CG1 . ILE E 1 313 ? 56.850  -1.597  63.383  1.00 22.12  ? 313 ILE E CG1 1 
ATOM   14978 C CG2 . ILE E 1 313 ? 56.351  -2.690  61.163  1.00 23.83  ? 313 ILE E CG2 1 
ATOM   14979 C CD1 . ILE E 1 313 ? 58.265  -1.169  63.110  1.00 26.55  ? 313 ILE E CD1 1 
ATOM   14980 N N   . ARG E 1 314 ? 54.013  -0.232  60.004  1.00 20.21  ? 314 ARG E N   1 
ATOM   14981 C CA  . ARG E 1 314 ? 53.358  -0.167  58.702  1.00 23.98  ? 314 ARG E CA  1 
ATOM   14982 C C   . ARG E 1 314 ? 53.681  1.139   57.985  1.00 23.81  ? 314 ARG E C   1 
ATOM   14983 O O   . ARG E 1 314 ? 53.893  1.147   56.773  1.00 22.84  ? 314 ARG E O   1 
ATOM   14984 C CB  . ARG E 1 314 ? 51.849  -0.319  58.858  1.00 22.15  ? 314 ARG E CB  1 
ATOM   14985 C CG  . ARG E 1 314 ? 51.167  -0.712  57.555  1.00 26.57  ? 314 ARG E CG  1 
ATOM   14986 C CD  . ARG E 1 314 ? 49.727  -1.117  57.771  1.00 23.16  ? 314 ARG E CD  1 
ATOM   14987 N NE  . ARG E 1 314 ? 48.922  0.063   58.038  1.00 23.74  ? 314 ARG E NE  1 
ATOM   14988 C CZ  . ARG E 1 314 ? 48.373  0.838   57.110  1.00 29.03  ? 314 ARG E CZ  1 
ATOM   14989 N NH1 . ARG E 1 314 ? 48.495  0.572   55.815  1.00 27.70  ? 314 ARG E NH1 1 
ATOM   14990 N NH2 . ARG E 1 314 ? 47.685  1.911   57.492  1.00 31.65  ? 314 ARG E NH2 1 
ATOM   14991 N N   . THR E 1 315 ? 53.725  2.252   58.721  1.00 24.20  ? 315 THR E N   1 
ATOM   14992 C CA  . THR E 1 315 ? 54.042  3.534   58.095  1.00 26.33  ? 315 THR E CA  1 
ATOM   14993 C C   . THR E 1 315 ? 55.465  3.544   57.539  1.00 27.08  ? 315 THR E C   1 
ATOM   14994 O O   . THR E 1 315 ? 55.694  4.041   56.432  1.00 28.57  ? 315 THR E O   1 
ATOM   14995 C CB  . THR E 1 315 ? 53.832  4.677   59.099  1.00 25.18  ? 315 THR E CB  1 
ATOM   14996 O OG1 . THR E 1 315 ? 52.440  4.803   59.395  1.00 25.69  ? 315 THR E OG1 1 
ATOM   14997 C CG2 . THR E 1 315 ? 54.292  5.975   58.525  1.00 27.25  ? 315 THR E CG2 1 
ATOM   14998 N N   . ILE E 1 316 ? 56.442  2.992   58.267  1.00 20.11  ? 316 ILE E N   1 
ATOM   14999 C CA  . ILE E 1 316 ? 57.766  2.960   57.668  1.00 26.77  ? 316 ILE E CA  1 
ATOM   15000 C C   . ILE E 1 316 ? 57.846  1.985   56.499  1.00 28.31  ? 316 ILE E C   1 
ATOM   15001 O O   . ILE E 1 316 ? 58.852  1.988   55.780  1.00 26.04  ? 316 ILE E O   1 
ATOM   15002 C CB  . ILE E 1 316 ? 58.903  2.655   58.669  1.00 26.52  ? 316 ILE E CB  1 
ATOM   15003 C CG1 . ILE E 1 316 ? 59.094  1.177   58.889  1.00 32.24  ? 316 ILE E CG1 1 
ATOM   15004 C CG2 . ILE E 1 316 ? 58.771  3.413   60.008  1.00 23.70  ? 316 ILE E CG2 1 
ATOM   15005 C CD1 . ILE E 1 316 ? 60.362  0.918   59.689  1.00 30.40  ? 316 ILE E CD1 1 
ATOM   15006 N N   . GLY E 1 317 ? 56.817  1.158   56.272  1.00 25.20  ? 317 GLY E N   1 
ATOM   15007 C CA  . GLY E 1 317 ? 56.720  0.476   54.991  1.00 24.90  ? 317 GLY E CA  1 
ATOM   15008 C C   . GLY E 1 317 ? 56.830  -1.038  54.934  1.00 26.93  ? 317 GLY E C   1 
ATOM   15009 O O   . GLY E 1 317 ? 56.886  -1.617  53.841  1.00 27.57  ? 317 GLY E O   1 
ATOM   15010 N N   . TYR E 1 318 ? 56.843  -1.704  56.079  1.00 24.31  ? 318 TYR E N   1 
ATOM   15011 C CA  . TYR E 1 318 ? 56.855  -3.149  56.075  1.00 20.94  ? 318 TYR E CA  1 
ATOM   15012 C C   . TYR E 1 318 ? 55.472  -3.708  55.733  1.00 28.72  ? 318 TYR E C   1 
ATOM   15013 O O   . TYR E 1 318 ? 54.428  -3.142  56.101  1.00 21.29  ? 318 TYR E O   1 
ATOM   15014 C CB  . TYR E 1 318 ? 57.302  -3.681  57.430  1.00 27.81  ? 318 TYR E CB  1 
ATOM   15015 C CG  . TYR E 1 318 ? 57.156  -5.169  57.517  1.00 24.23  ? 318 TYR E CG  1 
ATOM   15016 C CD1 . TYR E 1 318 ? 57.983  -6.017  56.771  1.00 24.81  ? 318 TYR E CD1 1 
ATOM   15017 C CD2 . TYR E 1 318 ? 56.169  -5.739  58.314  1.00 24.52  ? 318 TYR E CD2 1 
ATOM   15018 C CE1 . TYR E 1 318 ? 57.831  -7.405  56.836  1.00 22.62  ? 318 TYR E CE1 1 
ATOM   15019 C CE2 . TYR E 1 318 ? 56.017  -7.119  58.386  1.00 22.00  ? 318 TYR E CE2 1 
ATOM   15020 C CZ  . TYR E 1 318 ? 56.833  -7.941  57.639  1.00 20.15  ? 318 TYR E CZ  1 
ATOM   15021 O OH  . TYR E 1 318 ? 56.660  -9.308  57.728  1.00 23.31  ? 318 TYR E OH  1 
ATOM   15022 N N   . ARG E 1 319 ? 55.478  -4.831  55.015  1.00 21.61  ? 319 ARG E N   1 
ATOM   15023 C CA  . ARG E 1 319 ? 54.263  -5.500  54.561  1.00 27.31  ? 319 ARG E CA  1 
ATOM   15024 C C   . ARG E 1 319 ? 54.414  -6.984  54.826  1.00 23.98  ? 319 ARG E C   1 
ATOM   15025 O O   . ARG E 1 319 ? 55.437  -7.572  54.477  1.00 20.77  ? 319 ARG E O   1 
ATOM   15026 C CB  . ARG E 1 319 ? 54.015  -5.269  53.067  1.00 26.06  ? 319 ARG E CB  1 
ATOM   15027 C CG  . ARG E 1 319 ? 53.837  -3.808  52.699  1.00 22.50  ? 319 ARG E CG  1 
ATOM   15028 C CD  . ARG E 1 319 ? 52.582  -3.277  53.330  1.00 21.81  ? 319 ARG E CD  1 
ATOM   15029 N NE  . ARG E 1 319 ? 52.327  -1.895  52.939  1.00 22.73  ? 319 ARG E NE  1 
ATOM   15030 C CZ  . ARG E 1 319 ? 52.726  -0.830  53.620  1.00 20.13  ? 319 ARG E CZ  1 
ATOM   15031 N NH1 . ARG E 1 319 ? 53.418  -0.942  54.742  1.00 19.74  ? 319 ARG E NH1 1 
ATOM   15032 N NH2 . ARG E 1 319 ? 52.419  0.380   53.165  1.00 24.25  ? 319 ARG E NH2 1 
ATOM   15033 N N   . GLY E 1 320 ? 53.405  -7.587  55.442  1.00 25.13  ? 320 GLY E N   1 
ATOM   15034 C CA  . GLY E 1 320 ? 53.498  -8.988  55.792  1.00 21.92  ? 320 GLY E CA  1 
ATOM   15035 C C   . GLY E 1 320 ? 53.146  -9.196  57.248  1.00 20.84  ? 320 GLY E C   1 
ATOM   15036 O O   . GLY E 1 320 ? 52.485  -8.357  57.868  1.00 22.11  ? 320 GLY E O   1 
ATOM   15037 N N   . TYR E 1 321 ? 53.601  -10.320 57.800  1.00 21.62  ? 321 TYR E N   1 
ATOM   15038 C CA  . TYR E 1 321 ? 53.331  -10.668 59.188  1.00 18.85  ? 321 TYR E CA  1 
ATOM   15039 C C   . TYR E 1 321 ? 54.389  -10.097 60.124  1.00 17.85  ? 321 TYR E C   1 
ATOM   15040 O O   . TYR E 1 321 ? 55.581  -10.128 59.824  1.00 19.80  ? 321 TYR E O   1 
ATOM   15041 C CB  . TYR E 1 321 ? 53.245  -12.187 59.323  1.00 17.40  ? 321 TYR E CB  1 
ATOM   15042 C CG  . TYR E 1 321 ? 52.164  -12.729 58.437  1.00 18.13  ? 321 TYR E CG  1 
ATOM   15043 C CD1 . TYR E 1 321 ? 50.840  -12.679 58.839  1.00 19.34  ? 321 TYR E CD1 1 
ATOM   15044 C CD2 . TYR E 1 321 ? 52.451  -13.245 57.178  1.00 24.33  ? 321 TYR E CD2 1 
ATOM   15045 C CE1 . TYR E 1 321 ? 49.841  -13.139 58.045  1.00 19.65  ? 321 TYR E CE1 1 
ATOM   15046 C CE2 . TYR E 1 321 ? 51.431  -13.718 56.357  1.00 24.73  ? 321 TYR E CE2 1 
ATOM   15047 C CZ  . TYR E 1 321 ? 50.132  -13.654 56.807  1.00 19.93  ? 321 TYR E CZ  1 
ATOM   15048 O OH  . TYR E 1 321 ? 49.100  -14.104 56.036  1.00 23.62  ? 321 TYR E OH  1 
ATOM   15049 N N   . VAL E 1 322 ? 53.938  -9.544  61.249  1.00 20.08  ? 322 VAL E N   1 
ATOM   15050 C CA  . VAL E 1 322 ? 54.820  -9.082  62.320  1.00 20.10  ? 322 VAL E CA  1 
ATOM   15051 C C   . VAL E 1 322 ? 54.144  -9.363  63.655  1.00 21.10  ? 322 VAL E C   1 
ATOM   15052 O O   . VAL E 1 322 ? 52.919  -9.258  63.782  1.00 23.71  ? 322 VAL E O   1 
ATOM   15053 C CB  . VAL E 1 322 ? 55.160  -7.580  62.185  1.00 18.58  ? 322 VAL E CB  1 
ATOM   15054 C CG1 . VAL E 1 322 ? 53.904  -6.771  62.221  1.00 18.24  ? 322 VAL E CG1 1 
ATOM   15055 C CG2 . VAL E 1 322 ? 56.102  -7.138  63.316  1.00 17.26  ? 322 VAL E CG2 1 
ATOM   15056 N N   . ASN E 1 323 ? 54.939  -9.726  64.656  1.00 21.44  ? 323 ASN E N   1 
ATOM   15057 C CA  . ASN E 1 323 ? 54.407  -9.944  65.990  1.00 22.19  ? 323 ASN E CA  1 
ATOM   15058 C C   . ASN E 1 323 ? 55.213  -9.145  66.999  1.00 21.55  ? 323 ASN E C   1 
ATOM   15059 O O   . ASN E 1 323 ? 56.415  -8.925  66.825  1.00 25.15  ? 323 ASN E O   1 
ATOM   15060 C CB  . ASN E 1 323 ? 54.388  -11.464 66.338  1.00 18.96  ? 323 ASN E CB  1 
ATOM   15061 C CG  . ASN E 1 323 ? 55.757  -12.033 66.491  1.00 29.55  ? 323 ASN E CG  1 
ATOM   15062 O OD1 . ASN E 1 323 ? 56.354  -11.914 67.558  1.00 31.23  ? 323 ASN E OD1 1 
ATOM   15063 N ND2 . ASN E 1 323 ? 56.282  -12.659 65.423  1.00 27.03  ? 323 ASN E ND2 1 
ATOM   15064 N N   . ILE E 1 324 ? 54.545  -8.680  68.053  1.00 24.51  ? 324 ILE E N   1 
ATOM   15065 C CA  . ILE E 1 324 ? 55.217  -7.930  69.108  1.00 24.61  ? 324 ILE E CA  1 
ATOM   15066 C C   . ILE E 1 324 ? 55.041  -8.664  70.431  1.00 24.72  ? 324 ILE E C   1 
ATOM   15067 O O   . ILE E 1 324 ? 53.955  -9.166  70.738  1.00 28.45  ? 324 ILE E O   1 
ATOM   15068 C CB  . ILE E 1 324 ? 54.726  -6.467  69.192  1.00 24.92  ? 324 ILE E CB  1 
ATOM   15069 C CG1 . ILE E 1 324 ? 55.504  -5.723  70.295  1.00 22.36  ? 324 ILE E CG1 1 
ATOM   15070 C CG2 . ILE E 1 324 ? 53.211  -6.417  69.356  1.00 20.32  ? 324 ILE E CG2 1 
ATOM   15071 C CD1 . ILE E 1 324 ? 55.206  -4.235  70.414  1.00 24.50  ? 324 ILE E CD1 1 
ATOM   15072 N N   . ASP E 1 325 ? 56.129  -8.745  71.193  1.00 30.88  ? 325 ASP E N   1 
ATOM   15073 C CA  . ASP E 1 325 ? 56.263  -9.565  72.395  1.00 32.93  ? 325 ASP E CA  1 
ATOM   15074 C C   . ASP E 1 325 ? 56.050  -8.688  73.632  1.00 29.46  ? 325 ASP E C   1 
ATOM   15075 O O   . ASP E 1 325 ? 56.445  -7.522  73.639  1.00 28.49  ? 325 ASP E O   1 
ATOM   15076 C CB  . ASP E 1 325 ? 57.668  -10.196 72.381  1.00 30.91  ? 325 ASP E CB  1 
ATOM   15077 C CG  . ASP E 1 325 ? 57.841  -11.334 73.355  1.00 43.48  ? 325 ASP E CG  1 
ATOM   15078 O OD1 . ASP E 1 325 ? 57.850  -11.060 74.569  1.00 52.14  ? 325 ASP E OD1 1 
ATOM   15079 O OD2 . ASP E 1 325 ? 58.012  -12.502 72.919  1.00 53.82  ? 325 ASP E OD2 1 
ATOM   15080 N N   . GLY E 1 326 ? 55.437  -9.238  74.681  1.00 28.49  ? 326 GLY E N   1 
ATOM   15081 C CA  . GLY E 1 326 ? 55.193  -8.386  75.839  1.00 31.89  ? 326 GLY E CA  1 
ATOM   15082 C C   . GLY E 1 326 ? 54.835  -9.116  77.116  1.00 32.75  ? 326 GLY E C   1 
ATOM   15083 O O   . GLY E 1 326 ? 54.609  -10.330 77.136  1.00 29.60  ? 326 GLY E O   1 
ATOM   15084 N N   . ILE E 1 327 ? 54.776  -8.343  78.209  1.00 32.29  ? 327 ILE E N   1 
ATOM   15085 C CA  . ILE E 1 327 ? 54.448  -8.890  79.522  1.00 31.54  ? 327 ILE E CA  1 
ATOM   15086 C C   . ILE E 1 327 ? 53.587  -7.913  80.302  1.00 34.47  ? 327 ILE E C   1 
ATOM   15087 O O   . ILE E 1 327 ? 53.541  -6.711  80.019  1.00 35.79  ? 327 ILE E O   1 
ATOM   15088 C CB  . ILE E 1 327 ? 55.687  -9.236  80.380  1.00 28.50  ? 327 ILE E CB  1 
ATOM   15089 C CG1 . ILE E 1 327 ? 56.348  -7.960  80.896  1.00 30.50  ? 327 ILE E CG1 1 
ATOM   15090 C CG2 . ILE E 1 327 ? 56.692  -10.050 79.605  1.00 36.49  ? 327 ILE E CG2 1 
ATOM   15091 C CD1 . ILE E 1 327 ? 57.478  -8.251  81.878  1.00 35.54  ? 327 ILE E CD1 1 
ATOM   15092 N N   . VAL E 1 328 ? 52.919  -8.459  81.317  1.00 32.80  ? 328 VAL E N   1 
ATOM   15093 C CA  . VAL E 1 328 ? 52.198  -7.694  82.321  1.00 32.83  ? 328 VAL E CA  1 
ATOM   15094 C C   . VAL E 1 328 ? 52.720  -8.094  83.692  1.00 38.89  ? 328 VAL E C   1 
ATOM   15095 O O   . VAL E 1 328 ? 52.921  -9.282  83.969  1.00 39.66  ? 328 VAL E O   1 
ATOM   15096 C CB  . VAL E 1 328 ? 50.682  -7.932  82.243  1.00 35.48  ? 328 VAL E CB  1 
ATOM   15097 C CG1 . VAL E 1 328 ? 49.956  -7.028  83.255  1.00 33.47  ? 328 VAL E CG1 1 
ATOM   15098 C CG2 . VAL E 1 328 ? 50.196  -7.724  80.809  1.00 36.32  ? 328 VAL E CG2 1 
ATOM   15099 N N   . LEU E 1 329 ? 52.943  -7.105  84.545  1.00 36.75  ? 329 LEU E N   1 
ATOM   15100 C CA  . LEU E 1 329 ? 53.387  -7.365  85.904  1.00 42.15  ? 329 LEU E CA  1 
ATOM   15101 C C   . LEU E 1 329 ? 52.187  -7.476  86.839  1.00 44.29  ? 329 LEU E C   1 
ATOM   15102 O O   . LEU E 1 329 ? 51.083  -7.018  86.526  1.00 40.81  ? 329 LEU E O   1 
ATOM   15103 C CB  . LEU E 1 329 ? 54.325  -6.258  86.388  1.00 42.04  ? 329 LEU E CB  1 
ATOM   15104 C CG  . LEU E 1 329 ? 55.539  -5.938  85.513  1.00 40.49  ? 329 LEU E CG  1 
ATOM   15105 C CD1 . LEU E 1 329 ? 56.511  -5.069  86.286  1.00 37.70  ? 329 LEU E CD1 1 
ATOM   15106 C CD2 . LEU E 1 329 ? 56.217  -7.202  85.038  1.00 39.17  ? 329 LEU E CD2 1 
ATOM   15107 N N   . ASP E 1 330 ? 52.423  -8.104  87.999  1.00 43.18  ? 330 ASP E N   1 
ATOM   15108 C CA  . ASP E 1 330 ? 51.389  -8.212  89.026  1.00 47.28  ? 330 ASP E CA  1 
ATOM   15109 C C   . ASP E 1 330 ? 50.731  -6.865  89.303  1.00 40.19  ? 330 ASP E C   1 
ATOM   15110 O O   . ASP E 1 330 ? 49.513  -6.786  89.477  1.00 44.04  ? 330 ASP E O   1 
ATOM   15111 C CB  . ASP E 1 330 ? 51.987  -8.772  90.317  1.00 52.52  ? 330 ASP E CB  1 
ATOM   15112 C CG  . ASP E 1 330 ? 52.256  -10.263 90.242  1.00 59.61  ? 330 ASP E CG  1 
ATOM   15113 O OD1 . ASP E 1 330 ? 51.285  -11.056 90.181  1.00 62.92  ? 330 ASP E OD1 1 
ATOM   15114 O OD2 . ASP E 1 330 ? 53.447  -10.642 90.257  1.00 58.61  ? 330 ASP E OD2 1 
ATOM   15115 N N   . ASP E 1 331 ? 51.518  -5.792  89.342  1.00 43.43  ? 331 ASP E N   1 
ATOM   15116 C CA  . ASP E 1 331 ? 50.968  -4.465  89.577  1.00 44.08  ? 331 ASP E CA  1 
ATOM   15117 C C   . ASP E 1 331 ? 50.335  -3.852  88.324  1.00 47.45  ? 331 ASP E C   1 
ATOM   15118 O O   . ASP E 1 331 ? 50.014  -2.655  88.328  1.00 44.65  ? 331 ASP E O   1 
ATOM   15119 C CB  . ASP E 1 331 ? 52.049  -3.533  90.154  1.00 46.61  ? 331 ASP E CB  1 
ATOM   15120 C CG  . ASP E 1 331 ? 53.168  -3.189  89.155  1.00 47.94  ? 331 ASP E CG  1 
ATOM   15121 O OD1 . ASP E 1 331 ? 53.093  -3.566  87.962  1.00 49.27  ? 331 ASP E OD1 1 
ATOM   15122 O OD2 . ASP E 1 331 ? 54.133  -2.514  89.581  1.00 44.84  ? 331 ASP E OD2 1 
ATOM   15123 N N   . GLY E 1 332 ? 50.162  -4.633  87.258  1.00 44.93  ? 332 GLY E N   1 
ATOM   15124 C CA  . GLY E 1 332 ? 49.484  -4.149  86.074  1.00 42.69  ? 332 GLY E CA  1 
ATOM   15125 C C   . GLY E 1 332 ? 50.316  -3.329  85.112  1.00 43.22  ? 332 GLY E C   1 
ATOM   15126 O O   . GLY E 1 332 ? 49.745  -2.732  84.194  1.00 37.44  ? 332 GLY E O   1 
ATOM   15127 N N   . ARG E 1 333 ? 51.641  -3.289  85.274  1.00 45.89  ? 333 ARG E N   1 
ATOM   15128 C CA  . ARG E 1 333 ? 52.497  -2.583  84.323  1.00 43.43  ? 333 ARG E CA  1 
ATOM   15129 C C   . ARG E 1 333 ? 52.741  -3.436  83.082  1.00 37.19  ? 333 ARG E C   1 
ATOM   15130 O O   . ARG E 1 333 ? 53.000  -4.638  83.170  1.00 35.49  ? 333 ARG E O   1 
ATOM   15131 C CB  . ARG E 1 333 ? 53.838  -2.205  84.959  1.00 40.89  ? 333 ARG E CB  1 
ATOM   15132 C CG  . ARG E 1 333 ? 53.907  -0.782  85.526  1.00 40.33  ? 333 ARG E CG  1 
ATOM   15133 C CD  . ARG E 1 333 ? 55.254  -0.528  86.211  1.00 44.35  ? 333 ARG E CD  1 
ATOM   15134 N NE  . ARG E 1 333 ? 55.590  -1.532  87.222  1.00 36.89  ? 333 ARG E NE  1 
ATOM   15135 C CZ  . ARG E 1 333 ? 56.821  -1.756  87.670  1.00 42.94  ? 333 ARG E CZ  1 
ATOM   15136 N NH1 . ARG E 1 333 ? 57.865  -1.092  87.192  1.00 38.66  ? 333 ARG E NH1 1 
ATOM   15137 N NH2 . ARG E 1 333 ? 57.011  -2.667  88.625  1.00 43.01  ? 333 ARG E NH2 1 
ATOM   15138 N N   . VAL E 1 334 ? 52.651  -2.799  81.920  1.00 35.56  ? 334 VAL E N   1 
ATOM   15139 C CA  . VAL E 1 334 ? 52.857  -3.448  80.635  1.00 32.96  ? 334 VAL E CA  1 
ATOM   15140 C C   . VAL E 1 334 ? 54.214  -3.028  80.098  1.00 33.62  ? 334 VAL E C   1 
ATOM   15141 O O   . VAL E 1 334 ? 54.584  -1.854  80.193  1.00 35.26  ? 334 VAL E O   1 
ATOM   15142 C CB  . VAL E 1 334 ? 51.727  -3.083  79.654  1.00 33.79  ? 334 VAL E CB  1 
ATOM   15143 C CG1 . VAL E 1 334 ? 51.990  -3.675  78.291  1.00 28.12  ? 334 VAL E CG1 1 
ATOM   15144 C CG2 . VAL E 1 334 ? 50.384  -3.575  80.205  1.00 32.57  ? 334 VAL E CG2 1 
ATOM   15145 N N   . PHE E 1 335 ? 54.961  -3.991  79.560  1.00 27.73  ? 335 PHE E N   1 
ATOM   15146 C CA  . PHE E 1 335 ? 56.193  -3.739  78.827  1.00 28.74  ? 335 PHE E CA  1 
ATOM   15147 C C   . PHE E 1 335 ? 56.189  -4.582  77.558  1.00 32.72  ? 335 PHE E C   1 
ATOM   15148 O O   . PHE E 1 335 ? 55.819  -5.758  77.601  1.00 30.83  ? 335 PHE E O   1 
ATOM   15149 C CB  . PHE E 1 335 ? 57.444  -4.114  79.635  1.00 27.89  ? 335 PHE E CB  1 
ATOM   15150 C CG  . PHE E 1 335 ? 57.629  -3.330  80.903  1.00 35.22  ? 335 PHE E CG  1 
ATOM   15151 C CD1 . PHE E 1 335 ? 57.958  -1.982  80.867  1.00 32.20  ? 335 PHE E CD1 1 
ATOM   15152 C CD2 . PHE E 1 335 ? 57.492  -3.950  82.137  1.00 30.47  ? 335 PHE E CD2 1 
ATOM   15153 C CE1 . PHE E 1 335 ? 58.132  -1.258  82.050  1.00 33.05  ? 335 PHE E CE1 1 
ATOM   15154 C CE2 . PHE E 1 335 ? 57.658  -3.240  83.308  1.00 31.79  ? 335 PHE E CE2 1 
ATOM   15155 C CZ  . PHE E 1 335 ? 57.984  -1.893  83.271  1.00 33.36  ? 335 PHE E CZ  1 
ATOM   15156 N N   . PHE E 1 336 ? 56.633  -3.995  76.442  1.00 25.06  ? 336 PHE E N   1 
ATOM   15157 C CA  . PHE E 1 336 ? 56.890  -4.730  75.210  1.00 27.81  ? 336 PHE E CA  1 
ATOM   15158 C C   . PHE E 1 336 ? 58.388  -4.938  75.021  1.00 26.86  ? 336 PHE E C   1 
ATOM   15159 O O   . PHE E 1 336 ? 59.190  -4.035  75.283  1.00 26.71  ? 336 PHE E O   1 
ATOM   15160 C CB  . PHE E 1 336 ? 56.294  -3.994  74.010  1.00 27.06  ? 336 PHE E CB  1 
ATOM   15161 C CG  . PHE E 1 336 ? 54.805  -3.802  74.115  1.00 29.07  ? 336 PHE E CG  1 
ATOM   15162 C CD1 . PHE E 1 336 ? 53.932  -4.800  73.690  1.00 25.77  ? 336 PHE E CD1 1 
ATOM   15163 C CD2 . PHE E 1 336 ? 54.276  -2.644  74.664  1.00 24.72  ? 336 PHE E CD2 1 
ATOM   15164 C CE1 . PHE E 1 336 ? 52.571  -4.634  73.790  1.00 24.89  ? 336 PHE E CE1 1 
ATOM   15165 C CE2 . PHE E 1 336 ? 52.901  -2.478  74.772  1.00 29.24  ? 336 PHE E CE2 1 
ATOM   15166 C CZ  . PHE E 1 336 ? 52.052  -3.473  74.340  1.00 27.32  ? 336 PHE E CZ  1 
ATOM   15167 N N   . HIS E 1 337 ? 58.763  -6.131  74.556  1.00 28.14  ? 337 HIS E N   1 
ATOM   15168 C CA  . HIS E 1 337 ? 60.164  -6.556  74.544  1.00 33.91  ? 337 HIS E CA  1 
ATOM   15169 C C   . HIS E 1 337 ? 60.801  -6.512  73.160  1.00 29.04  ? 337 HIS E C   1 
ATOM   15170 O O   . HIS E 1 337 ? 61.916  -6.017  73.021  1.00 31.03  ? 337 HIS E O   1 
ATOM   15171 C CB  . HIS E 1 337 ? 60.309  -7.979  75.107  1.00 29.31  ? 337 HIS E CB  1 
ATOM   15172 C CG  . HIS E 1 337 ? 60.046  -8.088  76.574  1.00 36.26  ? 337 HIS E CG  1 
ATOM   15173 N ND1 . HIS E 1 337 ? 60.699  -7.312  77.512  1.00 42.97  ? 337 HIS E ND1 1 
ATOM   15174 C CD2 . HIS E 1 337 ? 59.219  -8.902  77.271  1.00 33.44  ? 337 HIS E CD2 1 
ATOM   15175 C CE1 . HIS E 1 337 ? 60.278  -7.638  78.722  1.00 30.72  ? 337 HIS E CE1 1 
ATOM   15176 N NE2 . HIS E 1 337 ? 59.387  -8.605  78.604  1.00 32.74  ? 337 HIS E NE2 1 
ATOM   15177 N N   . GLU E 1 338 ? 60.144  -7.061  72.140  1.00 26.61  ? 338 GLU E N   1 
ATOM   15178 C CA  . GLU E 1 338 ? 60.728  -7.089  70.804  1.00 27.21  ? 338 GLU E CA  1 
ATOM   15179 C C   . GLU E 1 338 ? 59.628  -7.242  69.768  1.00 28.71  ? 338 GLU E C   1 
ATOM   15180 O O   . GLU E 1 338 ? 58.460  -7.479  70.090  1.00 27.90  ? 338 GLU E O   1 
ATOM   15181 C CB  . GLU E 1 338 ? 61.757  -8.222  70.643  1.00 32.31  ? 338 GLU E CB  1 
ATOM   15182 C CG  . GLU E 1 338 ? 61.458  -9.487  71.404  1.00 35.46  ? 338 GLU E CG  1 
ATOM   15183 C CD  . GLU E 1 338 ? 62.581  -10.513 71.258  1.00 43.76  ? 338 GLU E CD  1 
ATOM   15184 O OE1 . GLU E 1 338 ? 62.917  -10.848 70.100  1.00 38.49  ? 338 GLU E OE1 1 
ATOM   15185 O OE2 . GLU E 1 338 ? 63.141  -10.964 72.291  1.00 43.89  ? 338 GLU E OE2 1 
ATOM   15186 N N   . ILE E 1 339 ? 60.029  -7.112  68.510  1.00 25.90  ? 339 ILE E N   1 
ATOM   15187 C CA  . ILE E 1 339 ? 59.179  -7.425  67.377  1.00 26.69  ? 339 ILE E CA  1 
ATOM   15188 C C   . ILE E 1 339 ? 59.942  -8.344  66.445  1.00 30.55  ? 339 ILE E C   1 
ATOM   15189 O O   . ILE E 1 339 ? 61.175  -8.295  66.364  1.00 25.18  ? 339 ILE E O   1 
ATOM   15190 C CB  . ILE E 1 339 ? 58.713  -6.170  66.616  1.00 21.18  ? 339 ILE E CB  1 
ATOM   15191 C CG1 . ILE E 1 339 ? 59.915  -5.388  66.104  1.00 25.51  ? 339 ILE E CG1 1 
ATOM   15192 C CG2 . ILE E 1 339 ? 57.786  -5.341  67.456  1.00 20.24  ? 339 ILE E CG2 1 
ATOM   15193 C CD1 . ILE E 1 339 ? 59.514  -4.354  65.054  1.00 29.36  ? 339 ILE E CD1 1 
ATOM   15194 N N   . ASN E 1 340 ? 59.191  -9.190  65.742  1.00 23.28  ? 340 ASN E N   1 
ATOM   15195 C CA  . ASN E 1 340 ? 59.728  -10.017 64.672  1.00 23.71  ? 340 ASN E CA  1 
ATOM   15196 C C   . ASN E 1 340 ? 58.899  -9.781  63.423  1.00 21.98  ? 340 ASN E C   1 
ATOM   15197 O O   . ASN E 1 340 ? 57.696  -10.050 63.418  1.00 23.75  ? 340 ASN E O   1 
ATOM   15198 C CB  . ASN E 1 340 ? 59.724  -11.489 65.071  1.00 27.93  ? 340 ASN E CB  1 
ATOM   15199 C CG  . ASN E 1 340 ? 60.650  -11.746 66.237  1.00 33.77  ? 340 ASN E CG  1 
ATOM   15200 O OD1 . ASN E 1 340 ? 61.871  -11.758 66.081  1.00 30.85  ? 340 ASN E OD1 1 
ATOM   15201 N ND2 . ASN E 1 340 ? 60.077  -11.884 67.427  1.00 25.93  ? 340 ASN E ND2 1 
ATOM   15202 N N   . ALA E 1 341 ? 59.534  -9.251  62.381  1.00 22.70  ? 341 ALA E N   1 
ATOM   15203 C CA  . ALA E 1 341 ? 58.877  -9.043  61.094  1.00 22.89  ? 341 ALA E CA  1 
ATOM   15204 C C   . ALA E 1 341 ? 59.082  -10.310 60.267  1.00 22.96  ? 341 ALA E C   1 
ATOM   15205 O O   . ALA E 1 341 ? 60.017  -10.426 59.479  1.00 23.02  ? 341 ALA E O   1 
ATOM   15206 C CB  . ALA E 1 341 ? 59.415  -7.792  60.416  1.00 23.85  ? 341 ALA E CB  1 
ATOM   15207 N N   . ARG E 1 342 ? 58.195  -11.282 60.486  1.00 23.37  ? 342 ARG E N   1 
ATOM   15208 C CA  . ARG E 1 342 ? 58.208  -12.596 59.849  1.00 25.31  ? 342 ARG E CA  1 
ATOM   15209 C C   . ARG E 1 342 ? 57.141  -13.465 60.502  1.00 23.02  ? 342 ARG E C   1 
ATOM   15210 O O   . ARG E 1 342 ? 56.470  -13.008 61.437  1.00 23.09  ? 342 ARG E O   1 
ATOM   15211 C CB  . ARG E 1 342 ? 59.589  -13.264 59.957  1.00 27.82  ? 342 ARG E CB  1 
ATOM   15212 C CG  . ARG E 1 342 ? 59.992  -13.725 61.351  1.00 28.61  ? 342 ARG E CG  1 
ATOM   15213 C CD  . ARG E 1 342 ? 61.486  -13.476 61.523  1.00 39.23  ? 342 ARG E CD  1 
ATOM   15214 N NE  . ARG E 1 342 ? 62.234  -14.595 62.077  1.00 43.37  ? 342 ARG E NE  1 
ATOM   15215 C CZ  . ARG E 1 342 ? 62.625  -14.679 63.344  1.00 58.96  ? 342 ARG E CZ  1 
ATOM   15216 N NH1 . ARG E 1 342 ? 62.352  -13.720 64.220  1.00 53.22  ? 342 ARG E NH1 1 
ATOM   15217 N NH2 . ARG E 1 342 ? 63.321  -15.746 63.741  1.00 58.29  ? 342 ARG E NH2 1 
ATOM   15218 N N   . TRP E 1 343 ? 56.960  -14.703 60.029  1.00 21.45  ? 343 TRP E N   1 
ATOM   15219 C CA  . TRP E 1 343 ? 55.943  -15.548 60.635  1.00 23.91  ? 343 TRP E CA  1 
ATOM   15220 C C   . TRP E 1 343 ? 56.311  -15.801 62.078  1.00 24.55  ? 343 TRP E C   1 
ATOM   15221 O O   . TRP E 1 343 ? 57.456  -16.152 62.374  1.00 21.35  ? 343 TRP E O   1 
ATOM   15222 C CB  . TRP E 1 343 ? 55.810  -16.894 59.923  1.00 23.41  ? 343 TRP E CB  1 
ATOM   15223 C CG  . TRP E 1 343 ? 55.383  -16.866 58.499  1.00 25.19  ? 343 TRP E CG  1 
ATOM   15224 C CD1 . TRP E 1 343 ? 54.659  -15.901 57.856  1.00 24.37  ? 343 TRP E CD1 1 
ATOM   15225 C CD2 . TRP E 1 343 ? 55.636  -17.887 57.539  1.00 22.92  ? 343 TRP E CD2 1 
ATOM   15226 N NE1 . TRP E 1 343 ? 54.450  -16.260 56.540  1.00 23.09  ? 343 TRP E NE1 1 
ATOM   15227 C CE2 . TRP E 1 343 ? 55.051  -17.477 56.323  1.00 28.87  ? 343 TRP E CE2 1 
ATOM   15228 C CE3 . TRP E 1 343 ? 56.300  -19.115 57.593  1.00 21.64  ? 343 TRP E CE3 1 
ATOM   15229 C CZ2 . TRP E 1 343 ? 55.118  -18.252 55.164  1.00 24.85  ? 343 TRP E CZ2 1 
ATOM   15230 C CZ3 . TRP E 1 343 ? 56.370  -19.882 56.444  1.00 27.38  ? 343 TRP E CZ3 1 
ATOM   15231 C CH2 . TRP E 1 343 ? 55.782  -19.448 55.244  1.00 28.43  ? 343 TRP E CH2 1 
ATOM   15232 N N   . SER E 1 344 ? 55.349  -15.619 62.982  1.00 23.36  ? 344 SER E N   1 
ATOM   15233 C CA  . SER E 1 344 ? 55.563  -16.180 64.303  1.00 19.87  ? 344 SER E CA  1 
ATOM   15234 C C   . SER E 1 344 ? 55.414  -17.685 64.193  1.00 22.59  ? 344 SER E C   1 
ATOM   15235 O O   . SER E 1 344 ? 54.774  -18.190 63.272  1.00 26.71  ? 344 SER E O   1 
ATOM   15236 C CB  . SER E 1 344 ? 54.565  -15.620 65.316  1.00 21.47  ? 344 SER E CB  1 
ATOM   15237 O OG  . SER E 1 344 ? 53.324  -16.318 65.247  1.00 22.40  ? 344 SER E OG  1 
ATOM   15238 N N   . GLY E 1 345 ? 56.020  -18.407 65.137  1.00 23.74  ? 345 GLY E N   1 
ATOM   15239 C CA  . GLY E 1 345 ? 55.813  -19.845 65.217  1.00 23.87  ? 345 GLY E CA  1 
ATOM   15240 C C   . GLY E 1 345 ? 54.368  -20.247 65.435  1.00 26.40  ? 345 GLY E C   1 
ATOM   15241 O O   . GLY E 1 345 ? 54.022  -21.416 65.215  1.00 26.40  ? 345 GLY E O   1 
ATOM   15242 N N   . GLY E 1 346 ? 53.516  -19.313 65.849  1.00 23.43  ? 346 GLY E N   1 
ATOM   15243 C CA  . GLY E 1 346 ? 52.121  -19.603 66.072  1.00 21.86  ? 346 GLY E CA  1 
ATOM   15244 C C   . GLY E 1 346 ? 51.196  -19.193 64.955  1.00 24.20  ? 346 GLY E C   1 
ATOM   15245 O O   . GLY E 1 346 ? 49.993  -19.458 65.051  1.00 25.60  ? 346 GLY E O   1 
ATOM   15246 N N   . LEU E 1 347 ? 51.702  -18.522 63.913  1.00 22.89  ? 347 LEU E N   1 
ATOM   15247 C CA  . LEU E 1 347 ? 50.833  -18.119 62.814  1.00 20.26  ? 347 LEU E CA  1 
ATOM   15248 C C   . LEU E 1 347 ? 50.082  -19.315 62.247  1.00 19.35  ? 347 LEU E C   1 
ATOM   15249 O O   . LEU E 1 347 ? 48.878  -19.233 61.999  1.00 21.56  ? 347 LEU E O   1 
ATOM   15250 C CB  . LEU E 1 347 ? 51.641  -17.432 61.711  1.00 24.07  ? 347 LEU E CB  1 
ATOM   15251 C CG  . LEU E 1 347 ? 50.788  -17.098 60.486  1.00 21.61  ? 347 LEU E CG  1 
ATOM   15252 C CD1 . LEU E 1 347 ? 49.642  -16.162 60.883  1.00 18.77  ? 347 LEU E CD1 1 
ATOM   15253 C CD2 . LEU E 1 347 ? 51.606  -16.513 59.384  1.00 18.42  ? 347 LEU E CD2 1 
ATOM   15254 N N   . ILE E 1 348 ? 50.775  -20.440 62.049  1.00 20.89  ? 348 ILE E N   1 
ATOM   15255 C CA  . ILE E 1 348 ? 50.122  -21.627 61.504  1.00 22.52  ? 348 ILE E CA  1 
ATOM   15256 C C   . ILE E 1 348 ? 49.031  -22.127 62.446  1.00 22.50  ? 348 ILE E C   1 
ATOM   15257 O O   . ILE E 1 348 ? 47.995  -22.628 61.999  1.00 21.08  ? 348 ILE E O   1 
ATOM   15258 C CB  . ILE E 1 348 ? 51.173  -22.717 61.209  1.00 23.53  ? 348 ILE E CB  1 
ATOM   15259 C CG1 . ILE E 1 348 ? 50.550  -23.861 60.424  1.00 23.79  ? 348 ILE E CG1 1 
ATOM   15260 C CG2 . ILE E 1 348 ? 51.838  -23.226 62.477  1.00 24.02  ? 348 ILE E CG2 1 
ATOM   15261 C CD1 . ILE E 1 348 ? 50.060  -23.403 59.064  1.00 28.84  ? 348 ILE E CD1 1 
ATOM   15262 N N   . TYR E 1 349 ? 49.234  -21.990 63.760  1.00 22.58  ? 349 TYR E N   1 
ATOM   15263 C CA  . TYR E 1 349 ? 48.227  -22.440 64.716  1.00 22.16  ? 349 TYR E CA  1 
ATOM   15264 C C   . TYR E 1 349 ? 46.931  -21.666 64.537  1.00 25.76  ? 349 TYR E C   1 
ATOM   15265 O O   . TYR E 1 349 ? 45.839  -22.244 64.458  1.00 21.95  ? 349 TYR E O   1 
ATOM   15266 C CB  . TYR E 1 349 ? 48.748  -22.260 66.133  1.00 25.98  ? 349 TYR E CB  1 
ATOM   15267 C CG  . TYR E 1 349 ? 50.005  -23.040 66.496  1.00 29.00  ? 349 TYR E CG  1 
ATOM   15268 C CD1 . TYR E 1 349 ? 50.374  -24.203 65.823  1.00 29.31  ? 349 TYR E CD1 1 
ATOM   15269 C CD2 . TYR E 1 349 ? 50.801  -22.613 67.541  1.00 25.54  ? 349 TYR E CD2 1 
ATOM   15270 C CE1 . TYR E 1 349 ? 51.535  -24.910 66.198  1.00 29.20  ? 349 TYR E CE1 1 
ATOM   15271 C CE2 . TYR E 1 349 ? 51.923  -23.292 67.921  1.00 27.51  ? 349 TYR E CE2 1 
ATOM   15272 C CZ  . TYR E 1 349 ? 52.295  -24.435 67.262  1.00 31.21  ? 349 TYR E CZ  1 
ATOM   15273 O OH  . TYR E 1 349 ? 53.435  -25.074 67.695  1.00 36.11  ? 349 TYR E OH  1 
ATOM   15274 N N   . HIS E 1 350 ? 47.042  -20.338 64.504  1.00 23.71  ? 350 HIS E N   1 
ATOM   15275 C CA  . HIS E 1 350 ? 45.917  -19.479 64.172  1.00 24.61  ? 350 HIS E CA  1 
ATOM   15276 C C   . HIS E 1 350 ? 45.335  -19.832 62.805  1.00 22.96  ? 350 HIS E C   1 
ATOM   15277 O O   . HIS E 1 350 ? 44.114  -19.885 62.647  1.00 23.56  ? 350 HIS E O   1 
ATOM   15278 C CB  . HIS E 1 350 ? 46.384  -18.019 64.229  1.00 24.80  ? 350 HIS E CB  1 
ATOM   15279 C CG  . HIS E 1 350 ? 45.454  -17.052 63.579  1.00 23.46  ? 350 HIS E CG  1 
ATOM   15280 N ND1 . HIS E 1 350 ? 44.308  -16.600 64.194  1.00 23.28  ? 350 HIS E ND1 1 
ATOM   15281 C CD2 . HIS E 1 350 ? 45.517  -16.421 62.384  1.00 21.14  ? 350 HIS E CD2 1 
ATOM   15282 C CE1 . HIS E 1 350 ? 43.690  -15.747 63.394  1.00 25.05  ? 350 HIS E CE1 1 
ATOM   15283 N NE2 . HIS E 1 350 ? 44.406  -15.621 62.290  1.00 25.49  ? 350 HIS E NE2 1 
ATOM   15284 N N   . THR E 1 351 ? 46.193  -20.105 61.818  1.00 24.53  ? 351 THR E N   1 
ATOM   15285 C CA  . THR E 1 351 ? 45.725  -20.531 60.496  1.00 24.28  ? 351 THR E CA  1 
ATOM   15286 C C   . THR E 1 351 ? 44.848  -21.776 60.583  1.00 26.24  ? 351 THR E C   1 
ATOM   15287 O O   . THR E 1 351 ? 43.799  -21.865 59.933  1.00 25.30  ? 351 THR E O   1 
ATOM   15288 C CB  . THR E 1 351 ? 46.917  -20.826 59.586  1.00 21.70  ? 351 THR E CB  1 
ATOM   15289 O OG1 . THR E 1 351 ? 47.792  -19.714 59.565  1.00 19.83  ? 351 THR E OG1 1 
ATOM   15290 C CG2 . THR E 1 351 ? 46.461  -21.189 58.153  1.00 20.63  ? 351 THR E CG2 1 
ATOM   15291 N N   . VAL E 1 352 ? 45.282  -22.778 61.342  1.00 25.70  ? 352 VAL E N   1 
ATOM   15292 C CA  . VAL E 1 352 ? 44.473  -23.988 61.414  1.00 23.64  ? 352 VAL E CA  1 
ATOM   15293 C C   . VAL E 1 352 ? 43.184  -23.719 62.171  1.00 23.72  ? 352 VAL E C   1 
ATOM   15294 O O   . VAL E 1 352 ? 42.104  -24.139 61.744  1.00 24.57  ? 352 VAL E O   1 
ATOM   15295 C CB  . VAL E 1 352 ? 45.269  -25.141 62.034  1.00 28.72  ? 352 VAL E CB  1 
ATOM   15296 C CG1 . VAL E 1 352 ? 44.405  -26.419 62.071  1.00 22.83  ? 352 VAL E CG1 1 
ATOM   15297 C CG2 . VAL E 1 352 ? 46.554  -25.348 61.240  1.00 19.78  ? 352 VAL E CG2 1 
ATOM   15298 N N   . ALA E 1 353 ? 43.269  -23.011 63.298  1.00 24.73  ? 353 ALA E N   1 
ATOM   15299 C CA  . ALA E 1 353 ? 42.065  -22.707 64.060  1.00 24.15  ? 353 ALA E CA  1 
ATOM   15300 C C   . ALA E 1 353 ? 41.042  -21.983 63.196  1.00 24.55  ? 353 ALA E C   1 
ATOM   15301 O O   . ALA E 1 353 ? 39.840  -22.246 63.289  1.00 23.98  ? 353 ALA E O   1 
ATOM   15302 C CB  . ALA E 1 353 ? 42.410  -21.861 65.285  1.00 25.61  ? 353 ALA E CB  1 
ATOM   15303 N N   . GLU E 1 354 ? 41.507  -21.076 62.337  1.00 24.37  ? 354 GLU E N   1 
ATOM   15304 C CA  . GLU E 1 354 ? 40.585  -20.278 61.544  1.00 27.41  ? 354 GLU E CA  1 
ATOM   15305 C C   . GLU E 1 354 ? 39.951  -21.112 60.441  1.00 31.02  ? 354 GLU E C   1 
ATOM   15306 O O   . GLU E 1 354 ? 38.770  -20.928 60.118  1.00 27.03  ? 354 GLU E O   1 
ATOM   15307 C CB  . GLU E 1 354 ? 41.319  -19.065 60.969  1.00 28.15  ? 354 GLU E CB  1 
ATOM   15308 C CG  . GLU E 1 354 ? 40.605  -18.352 59.843  1.00 32.46  ? 354 GLU E CG  1 
ATOM   15309 C CD  . GLU E 1 354 ? 41.214  -16.974 59.562  1.00 40.42  ? 354 GLU E CD  1 
ATOM   15310 O OE1 . GLU E 1 354 ? 42.255  -16.892 58.864  1.00 43.00  ? 354 GLU E OE1 1 
ATOM   15311 O OE2 . GLU E 1 354 ? 40.657  -15.974 60.054  1.00 35.39  ? 354 GLU E OE2 1 
ATOM   15312 N N   . ARG E 1 355 ? 40.713  -22.059 59.880  1.00 24.07  ? 355 ARG E N   1 
ATOM   15313 C CA  . ARG E 1 355 ? 40.199  -22.876 58.792  1.00 24.80  ? 355 ARG E CA  1 
ATOM   15314 C C   . ARG E 1 355 ? 39.216  -23.926 59.292  1.00 23.91  ? 355 ARG E C   1 
ATOM   15315 O O   . ARG E 1 355 ? 38.226  -24.222 58.620  1.00 30.09  ? 355 ARG E O   1 
ATOM   15316 C CB  . ARG E 1 355 ? 41.360  -23.525 58.044  1.00 22.54  ? 355 ARG E CB  1 
ATOM   15317 C CG  . ARG E 1 355 ? 42.222  -22.514 57.280  1.00 24.41  ? 355 ARG E CG  1 
ATOM   15318 C CD  . ARG E 1 355 ? 43.328  -23.213 56.520  1.00 23.81  ? 355 ARG E CD  1 
ATOM   15319 N NE  . ARG E 1 355 ? 42.829  -23.711 55.248  1.00 26.71  ? 355 ARG E NE  1 
ATOM   15320 C CZ  . ARG E 1 355 ? 43.607  -24.115 54.253  1.00 32.19  ? 355 ARG E CZ  1 
ATOM   15321 N NH1 . ARG E 1 355 ? 44.930  -24.106 54.359  1.00 24.90  ? 355 ARG E NH1 1 
ATOM   15322 N NH2 . ARG E 1 355 ? 43.046  -24.543 53.126  1.00 31.87  ? 355 ARG E NH2 1 
ATOM   15323 N N   . LEU E 1 356 ? 39.445  -24.478 60.472  1.00 28.02  ? 356 LEU E N   1 
ATOM   15324 C CA  . LEU E 1 356 ? 38.583  -25.542 60.972  1.00 22.12  ? 356 LEU E CA  1 
ATOM   15325 C C   . LEU E 1 356 ? 37.437  -25.018 61.828  1.00 25.31  ? 356 LEU E C   1 
ATOM   15326 O O   . LEU E 1 356 ? 36.362  -25.621 61.849  1.00 21.11  ? 356 LEU E O   1 
ATOM   15327 C CB  . LEU E 1 356 ? 39.415  -26.531 61.783  1.00 23.43  ? 356 LEU E CB  1 
ATOM   15328 C CG  . LEU E 1 356 ? 40.490  -27.312 61.022  1.00 27.21  ? 356 LEU E CG  1 
ATOM   15329 C CD1 . LEU E 1 356 ? 41.274  -28.168 62.016  1.00 25.75  ? 356 LEU E CD1 1 
ATOM   15330 C CD2 . LEU E 1 356 ? 39.845  -28.186 59.944  1.00 21.87  ? 356 LEU E CD2 1 
ATOM   15331 N N   . LEU E 1 357 ? 37.641  -23.912 62.537  1.00 24.50  ? 357 LEU E N   1 
ATOM   15332 C CA  . LEU E 1 357 ? 36.646  -23.410 63.465  1.00 26.16  ? 357 LEU E CA  1 
ATOM   15333 C C   . LEU E 1 357 ? 36.074  -22.061 63.081  1.00 26.27  ? 357 LEU E C   1 
ATOM   15334 O O   . LEU E 1 357 ? 35.210  -21.560 63.805  1.00 32.99  ? 357 LEU E O   1 
ATOM   15335 C CB  . LEU E 1 357 ? 37.222  -23.315 64.888  1.00 24.64  ? 357 LEU E CB  1 
ATOM   15336 C CG  . LEU E 1 357 ? 37.793  -24.629 65.421  1.00 28.92  ? 357 LEU E CG  1 
ATOM   15337 C CD1 . LEU E 1 357 ? 38.423  -24.450 66.789  1.00 27.67  ? 357 LEU E CD1 1 
ATOM   15338 C CD2 . LEU E 1 357 ? 36.717  -25.707 65.429  1.00 23.16  ? 357 LEU E CD2 1 
ATOM   15339 N N   . GLY E 1 358 ? 36.518  -21.453 61.985  1.00 25.58  ? 358 GLY E N   1 
ATOM   15340 C CA  . GLY E 1 358 ? 35.963  -20.181 61.574  1.00 23.82  ? 358 GLY E CA  1 
ATOM   15341 C C   . GLY E 1 358 ? 36.706  -18.994 62.168  1.00 29.27  ? 358 GLY E C   1 
ATOM   15342 O O   . GLY E 1 358 ? 37.423  -19.101 63.164  1.00 26.16  ? 358 GLY E O   1 
ATOM   15343 N N   . HIS E 1 359 ? 36.509  -17.826 61.530  1.00 29.79  ? 359 HIS E N   1 
ATOM   15344 C CA  . HIS E 1 359 ? 37.241  -16.618 61.912  1.00 29.19  ? 359 HIS E CA  1 
ATOM   15345 C C   . HIS E 1 359 ? 37.018  -16.237 63.368  1.00 27.88  ? 359 HIS E C   1 
ATOM   15346 O O   . HIS E 1 359 ? 37.916  -15.681 64.009  1.00 29.42  ? 359 HIS E O   1 
ATOM   15347 C CB  . HIS E 1 359 ? 36.827  -15.453 61.025  1.00 26.80  ? 359 HIS E CB  1 
ATOM   15348 C CG  . HIS E 1 359 ? 35.379  -15.094 61.145  1.00 28.50  ? 359 HIS E CG  1 
ATOM   15349 N ND1 . HIS E 1 359 ? 34.913  -14.198 62.081  1.00 27.01  ? 359 HIS E ND1 1 
ATOM   15350 C CD2 . HIS E 1 359 ? 34.296  -15.491 60.431  1.00 30.56  ? 359 HIS E CD2 1 
ATOM   15351 C CE1 . HIS E 1 359 ? 33.603  -14.074 61.956  1.00 33.25  ? 359 HIS E CE1 1 
ATOM   15352 N NE2 . HIS E 1 359 ? 33.204  -14.844 60.958  1.00 28.85  ? 359 HIS E NE2 1 
ATOM   15353 N N   . ASP E 1 360 ? 35.833  -16.492 63.896  1.00 29.07  ? 360 ASP E N   1 
ATOM   15354 C CA  . ASP E 1 360 ? 35.462  -16.106 65.253  1.00 31.69  ? 360 ASP E CA  1 
ATOM   15355 C C   . ASP E 1 360 ? 35.897  -17.123 66.312  1.00 28.75  ? 360 ASP E C   1 
ATOM   15356 O O   . ASP E 1 360 ? 35.351  -17.070 67.415  1.00 33.30  ? 360 ASP E O   1 
ATOM   15357 C CB  . ASP E 1 360 ? 33.940  -15.908 65.345  1.00 34.38  ? 360 ASP E CB  1 
ATOM   15358 C CG  . ASP E 1 360 ? 33.155  -17.126 64.830  1.00 41.65  ? 360 ASP E CG  1 
ATOM   15359 O OD1 . ASP E 1 360 ? 33.730  -18.238 64.773  1.00 36.80  ? 360 ASP E OD1 1 
ATOM   15360 O OD2 . ASP E 1 360 ? 31.944  -16.993 64.521  1.00 53.42  ? 360 ASP E OD2 1 
ATOM   15361 N N   . TYR E 1 361 ? 36.840  -18.028 66.010  1.00 27.06  ? 361 TYR E N   1 
ATOM   15362 C CA  . TYR E 1 361 ? 37.096  -19.173 66.886  1.00 29.25  ? 361 TYR E CA  1 
ATOM   15363 C C   . TYR E 1 361 ? 37.468  -18.746 68.301  1.00 27.83  ? 361 TYR E C   1 
ATOM   15364 O O   . TYR E 1 361 ? 37.091  -19.409 69.269  1.00 29.17  ? 361 TYR E O   1 
ATOM   15365 C CB  . TYR E 1 361 ? 38.197  -20.064 66.296  1.00 30.41  ? 361 TYR E CB  1 
ATOM   15366 C CG  . TYR E 1 361 ? 39.602  -19.475 66.352  1.00 26.90  ? 361 TYR E CG  1 
ATOM   15367 C CD1 . TYR E 1 361 ? 40.365  -19.551 67.519  1.00 23.01  ? 361 TYR E CD1 1 
ATOM   15368 C CD2 . TYR E 1 361 ? 40.171  -18.869 65.234  1.00 23.25  ? 361 TYR E CD2 1 
ATOM   15369 C CE1 . TYR E 1 361 ? 41.629  -19.027 67.581  1.00 22.27  ? 361 TYR E CE1 1 
ATOM   15370 C CE2 . TYR E 1 361 ? 41.440  -18.338 65.284  1.00 20.79  ? 361 TYR E CE2 1 
ATOM   15371 C CZ  . TYR E 1 361 ? 42.171  -18.424 66.467  1.00 26.62  ? 361 TYR E CZ  1 
ATOM   15372 O OH  . TYR E 1 361 ? 43.443  -17.903 66.563  1.00 20.15  ? 361 TYR E OH  1 
ATOM   15373 N N   . ALA E 1 362 ? 38.218  -17.652 68.444  1.00 29.52  ? 362 ALA E N   1 
ATOM   15374 C CA  . ALA E 1 362 ? 38.732  -17.288 69.762  1.00 32.53  ? 362 ALA E CA  1 
ATOM   15375 C C   . ALA E 1 362 ? 37.633  -16.895 70.731  1.00 31.79  ? 362 ALA E C   1 
ATOM   15376 O O   . ALA E 1 362 ? 37.895  -16.832 71.934  1.00 39.44  ? 362 ALA E O   1 
ATOM   15377 C CB  . ALA E 1 362 ? 39.754  -16.144 69.659  1.00 29.55  ? 362 ALA E CB  1 
ATOM   15378 N N   . ARG E 1 363 ? 36.412  -16.654 70.250  1.00 31.58  ? 363 ARG E N   1 
ATOM   15379 C CA  . ARG E 1 363 ? 35.325  -16.277 71.147  1.00 35.23  ? 363 ARG E CA  1 
ATOM   15380 C C   . ARG E 1 363 ? 34.908  -17.445 72.040  1.00 39.57  ? 363 ARG E C   1 
ATOM   15381 O O   . ARG E 1 363 ? 34.621  -17.255 73.230  1.00 33.62  ? 363 ARG E O   1 
ATOM   15382 C CB  . ARG E 1 363 ? 34.140  -15.751 70.330  1.00 41.12  ? 363 ARG E CB  1 
ATOM   15383 C CG  . ARG E 1 363 ? 34.364  -14.339 69.718  1.00 41.51  ? 363 ARG E CG  1 
ATOM   15384 C CD  . ARG E 1 363 ? 33.107  -13.749 69.052  1.00 39.72  ? 363 ARG E CD  1 
ATOM   15385 N NE  . ARG E 1 363 ? 32.163  -13.264 70.054  1.00 55.13  ? 363 ARG E NE  1 
ATOM   15386 C CZ  . ARG E 1 363 ? 31.770  -12.003 70.193  1.00 55.86  ? 363 ARG E CZ  1 
ATOM   15387 N NH1 . ARG E 1 363 ? 32.170  -11.053 69.363  1.00 54.87  ? 363 ARG E NH1 1 
ATOM   15388 N NH2 . ARG E 1 363 ? 30.966  -11.684 71.202  1.00 51.36  ? 363 ARG E NH2 1 
ATOM   15389 N N   . ASN E 1 364 ? 34.889  -18.672 71.499  1.00 38.27  ? 364 ASN E N   1 
ATOM   15390 C CA  . ASN E 1 364 ? 34.507  -19.829 72.297  1.00 34.49  ? 364 ASN E CA  1 
ATOM   15391 C C   . ASN E 1 364 ? 35.495  -20.984 72.271  1.00 39.00  ? 364 ASN E C   1 
ATOM   15392 O O   . ASN E 1 364 ? 35.174  -22.048 72.815  1.00 34.84  ? 364 ASN E O   1 
ATOM   15393 C CB  . ASN E 1 364 ? 33.151  -20.378 71.842  1.00 40.51  ? 364 ASN E CB  1 
ATOM   15394 C CG  . ASN E 1 364 ? 32.105  -19.314 71.738  1.00 44.20  ? 364 ASN E CG  1 
ATOM   15395 O OD1 . ASN E 1 364 ? 31.476  -19.162 70.687  1.00 48.20  ? 364 ASN E OD1 1 
ATOM   15396 N ND2 . ASN E 1 364 ? 31.903  -18.557 72.827  1.00 38.06  ? 364 ASN E ND2 1 
ATOM   15397 N N   . ASN E 1 365 ? 36.663  -20.837 71.647  1.00 35.56  ? 365 ASN E N   1 
ATOM   15398 C CA  . ASN E 1 365 ? 37.572  -21.966 71.514  1.00 31.58  ? 365 ASN E CA  1 
ATOM   15399 C C   . ASN E 1 365 ? 38.951  -21.607 72.037  1.00 34.08  ? 365 ASN E C   1 
ATOM   15400 O O   . ASN E 1 365 ? 39.349  -20.437 72.058  1.00 35.25  ? 365 ASN E O   1 
ATOM   15401 C CB  . ASN E 1 365 ? 37.691  -22.435 70.069  1.00 30.11  ? 365 ASN E CB  1 
ATOM   15402 C CG  . ASN E 1 365 ? 36.394  -22.994 69.533  1.00 30.44  ? 365 ASN E CG  1 
ATOM   15403 O OD1 . ASN E 1 365 ? 36.109  -24.179 69.678  1.00 26.25  ? 365 ASN E OD1 1 
ATOM   15404 N ND2 . ASN E 1 365 ? 35.597  -22.137 68.915  1.00 31.81  ? 365 ASN E ND2 1 
ATOM   15405 N N   . PHE E 1 366 ? 39.669  -22.638 72.466  1.00 31.20  ? 366 PHE E N   1 
ATOM   15406 C CA  . PHE E 1 366 ? 41.063  -22.532 72.850  1.00 28.71  ? 366 PHE E CA  1 
ATOM   15407 C C   . PHE E 1 366 ? 41.858  -23.543 72.043  1.00 35.95  ? 366 PHE E C   1 
ATOM   15408 O O   . PHE E 1 366 ? 41.326  -24.566 71.585  1.00 30.65  ? 366 PHE E O   1 
ATOM   15409 C CB  . PHE E 1 366 ? 41.277  -22.790 74.352  1.00 29.68  ? 366 PHE E CB  1 
ATOM   15410 C CG  . PHE E 1 366 ? 40.336  -22.026 75.238  1.00 37.79  ? 366 PHE E CG  1 
ATOM   15411 C CD1 . PHE E 1 366 ? 39.085  -22.545 75.556  1.00 32.48  ? 366 PHE E CD1 1 
ATOM   15412 C CD2 . PHE E 1 366 ? 40.692  -20.782 75.752  1.00 35.43  ? 366 PHE E CD2 1 
ATOM   15413 C CE1 . PHE E 1 366 ? 38.203  -21.835 76.362  1.00 37.57  ? 366 PHE E CE1 1 
ATOM   15414 C CE2 . PHE E 1 366 ? 39.815  -20.072 76.566  1.00 38.37  ? 366 PHE E CE2 1 
ATOM   15415 C CZ  . PHE E 1 366 ? 38.570  -20.596 76.877  1.00 36.68  ? 366 PHE E CZ  1 
ATOM   15416 N N   . PHE E 1 367 ? 43.136  -23.246 71.846  1.00 33.45  ? 367 PHE E N   1 
ATOM   15417 C CA  . PHE E 1 367 ? 44.020  -24.258 71.315  1.00 29.10  ? 367 PHE E CA  1 
ATOM   15418 C C   . PHE E 1 367 ? 45.325  -24.212 72.083  1.00 32.74  ? 367 PHE E C   1 
ATOM   15419 O O   . PHE E 1 367 ? 45.675  -23.209 72.714  1.00 33.86  ? 367 PHE E O   1 
ATOM   15420 C CB  . PHE E 1 367 ? 44.204  -24.151 69.782  1.00 26.33  ? 367 PHE E CB  1 
ATOM   15421 C CG  . PHE E 1 367 ? 44.916  -22.911 69.278  1.00 33.56  ? 367 PHE E CG  1 
ATOM   15422 C CD1 . PHE E 1 367 ? 46.287  -22.750 69.434  1.00 33.02  ? 367 PHE E CD1 1 
ATOM   15423 C CD2 . PHE E 1 367 ? 44.213  -21.954 68.539  1.00 32.61  ? 367 PHE E CD2 1 
ATOM   15424 C CE1 . PHE E 1 367 ? 46.935  -21.633 68.918  1.00 34.61  ? 367 PHE E CE1 1 
ATOM   15425 C CE2 . PHE E 1 367 ? 44.844  -20.838 68.012  1.00 29.58  ? 367 PHE E CE2 1 
ATOM   15426 C CZ  . PHE E 1 367 ? 46.213  -20.673 68.194  1.00 34.65  ? 367 PHE E CZ  1 
ATOM   15427 N N   . SER E 1 368 ? 46.004  -25.355 72.061  1.00 33.62  ? 368 SER E N   1 
ATOM   15428 C CA  . SER E 1 368 ? 47.268  -25.554 72.739  1.00 25.93  ? 368 SER E CA  1 
ATOM   15429 C C   . SER E 1 368 ? 48.112  -26.486 71.890  1.00 27.51  ? 368 SER E C   1 
ATOM   15430 O O   . SER E 1 368 ? 47.610  -27.474 71.340  1.00 25.14  ? 368 SER E O   1 
ATOM   15431 C CB  . SER E 1 368 ? 47.076  -26.138 74.134  1.00 29.67  ? 368 SER E CB  1 
ATOM   15432 O OG  . SER E 1 368 ? 48.247  -25.939 74.899  1.00 34.12  ? 368 SER E OG  1 
ATOM   15433 N N   . SER E 1 369 ? 49.384  -26.147 71.758  1.00 26.02  ? 369 SER E N   1 
ATOM   15434 C CA  . SER E 1 369 ? 50.305  -26.961 70.997  1.00 26.50  ? 369 SER E CA  1 
ATOM   15435 C C   . SER E 1 369 ? 51.192  -27.712 71.973  1.00 29.34  ? 369 SER E C   1 
ATOM   15436 O O   . SER E 1 369 ? 51.412  -27.266 73.105  1.00 29.73  ? 369 SER E O   1 
ATOM   15437 C CB  . SER E 1 369 ? 51.138  -26.127 70.018  1.00 26.69  ? 369 SER E CB  1 
ATOM   15438 O OG  . SER E 1 369 ? 52.134  -25.345 70.659  1.00 31.77  ? 369 SER E OG  1 
ATOM   15439 N N   . ILE E 1 370 ? 51.623  -28.893 71.539  1.00 29.11  ? 370 ILE E N   1 
ATOM   15440 C CA  . ILE E 1 370 ? 52.624  -29.710 72.210  1.00 28.18  ? 370 ILE E CA  1 
ATOM   15441 C C   . ILE E 1 370 ? 53.760  -29.904 71.218  1.00 29.43  ? 370 ILE E C   1 
ATOM   15442 O O   . ILE E 1 370 ? 53.553  -30.457 70.132  1.00 30.45  ? 370 ILE E O   1 
ATOM   15443 C CB  . ILE E 1 370 ? 52.065  -31.072 72.664  1.00 28.30  ? 370 ILE E CB  1 
ATOM   15444 C CG1 . ILE E 1 370 ? 50.713  -30.904 73.366  1.00 29.52  ? 370 ILE E CG1 1 
ATOM   15445 C CG2 . ILE E 1 370 ? 53.077  -31.794 73.562  1.00 28.69  ? 370 ILE E CG2 1 
ATOM   15446 C CD1 . ILE E 1 370 ? 50.032  -32.225 73.731  1.00 26.40  ? 370 ILE E CD1 1 
ATOM   15447 N N   . LEU E 1 371 ? 54.940  -29.437 71.578  1.00 31.65  ? 371 LEU E N   1 
ATOM   15448 C CA  . LEU E 1 371 ? 56.113  -29.611 70.744  1.00 36.56  ? 371 LEU E CA  1 
ATOM   15449 C C   . LEU E 1 371 ? 56.867  -30.877 71.079  1.00 37.77  ? 371 LEU E C   1 
ATOM   15450 O O   . LEU E 1 371 ? 57.782  -31.257 70.337  1.00 38.04  ? 371 LEU E O   1 
ATOM   15451 C CB  . LEU E 1 371 ? 57.040  -28.406 70.908  1.00 42.16  ? 371 LEU E CB  1 
ATOM   15452 C CG  . LEU E 1 371 ? 56.329  -27.066 70.732  1.00 38.68  ? 371 LEU E CG  1 
ATOM   15453 C CD1 . LEU E 1 371 ? 57.279  -25.957 71.080  1.00 43.92  ? 371 LEU E CD1 1 
ATOM   15454 C CD2 . LEU E 1 371 ? 55.804  -26.899 69.311  1.00 39.70  ? 371 LEU E CD2 1 
ATOM   15455 N N   . ASN E 1 372 ? 56.435  -31.563 72.131  1.00 41.00  ? 372 ASN E N   1 
ATOM   15456 C CA  . ASN E 1 372 ? 57.239  -32.486 72.913  1.00 40.05  ? 372 ASN E CA  1 
ATOM   15457 C C   . ASN E 1 372 ? 57.008  -33.960 72.601  1.00 40.95  ? 372 ASN E C   1 
ATOM   15458 O O   . ASN E 1 372 ? 57.895  -34.767 72.891  1.00 45.13  ? 372 ASN E O   1 
ATOM   15459 C CB  . ASN E 1 372 ? 56.945  -32.262 74.402  1.00 40.82  ? 372 ASN E CB  1 
ATOM   15460 C CG  . ASN E 1 372 ? 58.140  -31.760 75.157  1.00 56.32  ? 372 ASN E CG  1 
ATOM   15461 O OD1 . ASN E 1 372 ? 58.995  -31.069 74.605  1.00 64.89  ? 372 ASN E OD1 1 
ATOM   15462 N ND2 . ASN E 1 372 ? 58.227  -32.125 76.429  1.00 62.97  ? 372 ASN E ND2 1 
ATOM   15463 N N   . VAL E 1 373 ? 55.851  -34.342 72.043  1.00 31.32  ? 373 VAL E N   1 
ATOM   15464 C CA  . VAL E 1 373 ? 55.508  -35.764 71.961  1.00 38.15  ? 373 VAL E CA  1 
ATOM   15465 C C   . VAL E 1 373 ? 56.576  -36.564 71.187  1.00 34.99  ? 373 VAL E C   1 
ATOM   15466 O O   . VAL E 1 373 ? 57.183  -36.077 70.222  1.00 32.11  ? 373 VAL E O   1 
ATOM   15467 C CB  . VAL E 1 373 ? 54.102  -35.978 71.358  1.00 33.00  ? 373 VAL E CB  1 
ATOM   15468 C CG1 . VAL E 1 373 ? 53.471  -34.677 70.921  1.00 34.36  ? 373 VAL E CG1 1 
ATOM   15469 C CG2 . VAL E 1 373 ? 54.109  -36.998 70.197  1.00 31.74  ? 373 VAL E CG2 1 
ATOM   15470 N N   . VAL E 1 374 ? 56.785  -37.813 71.615  1.00 30.86  ? 374 VAL E N   1 
ATOM   15471 C CA  . VAL E 1 374 ? 57.769  -38.729 71.028  1.00 34.92  ? 374 VAL E CA  1 
ATOM   15472 C C   . VAL E 1 374 ? 57.552  -38.873 69.527  1.00 37.22  ? 374 VAL E C   1 
ATOM   15473 O O   . VAL E 1 374 ? 56.429  -39.151 69.077  1.00 36.38  ? 374 VAL E O   1 
ATOM   15474 C CB  . VAL E 1 374 ? 57.720  -40.117 71.690  1.00 38.77  ? 374 VAL E CB  1 
ATOM   15475 C CG1 . VAL E 1 374 ? 58.681  -41.072 70.988  1.00 31.69  ? 374 VAL E CG1 1 
ATOM   15476 C CG2 . VAL E 1 374 ? 58.011  -40.031 73.191  1.00 32.14  ? 374 VAL E CG2 1 
ATOM   15477 N N   . PRO E 1 375 ? 58.591  -38.691 68.720  1.00 32.82  ? 375 PRO E N   1 
ATOM   15478 C CA  . PRO E 1 375 ? 58.417  -38.763 67.267  1.00 33.50  ? 375 PRO E CA  1 
ATOM   15479 C C   . PRO E 1 375 ? 58.002  -40.154 66.812  1.00 36.89  ? 375 PRO E C   1 
ATOM   15480 O O   . PRO E 1 375 ? 58.594  -41.168 67.203  1.00 29.22  ? 375 PRO E O   1 
ATOM   15481 C CB  . PRO E 1 375 ? 59.800  -38.386 66.727  1.00 32.09  ? 375 PRO E CB  1 
ATOM   15482 C CG  . PRO E 1 375 ? 60.405  -37.551 67.817  1.00 36.42  ? 375 PRO E CG  1 
ATOM   15483 C CD  . PRO E 1 375 ? 59.923  -38.185 69.093  1.00 35.00  ? 375 PRO E CD  1 
ATOM   15484 N N   . ALA E 1 376 ? 56.980  -40.190 65.960  1.00 32.57  ? 376 ALA E N   1 
ATOM   15485 C CA  . ALA E 1 376 ? 56.577  -41.414 65.296  1.00 34.72  ? 376 ALA E CA  1 
ATOM   15486 C C   . ALA E 1 376 ? 56.150  -41.075 63.879  1.00 35.64  ? 376 ALA E C   1 
ATOM   15487 O O   . ALA E 1 376 ? 55.907  -39.910 63.547  1.00 35.08  ? 376 ALA E O   1 
ATOM   15488 C CB  . ALA E 1 376 ? 55.449  -42.115 66.061  1.00 33.51  ? 376 ALA E CB  1 
ATOM   15489 N N   . GLY E 1 377 ? 56.090  -42.101 63.031  1.00 30.99  ? 377 GLY E N   1 
ATOM   15490 C CA  . GLY E 1 377 ? 55.438  -41.938 61.746  1.00 37.39  ? 377 GLY E CA  1 
ATOM   15491 C C   . GLY E 1 377 ? 53.998  -41.471 61.896  1.00 36.01  ? 377 GLY E C   1 
ATOM   15492 O O   . GLY E 1 377 ? 53.360  -41.620 62.946  1.00 32.91  ? 377 GLY E O   1 
ATOM   15493 N N   . LEU E 1 378 ? 53.479  -40.892 60.814  1.00 31.81  ? 378 LEU E N   1 
ATOM   15494 C CA  . LEU E 1 378 ? 52.140  -40.311 60.853  1.00 31.20  ? 378 LEU E CA  1 
ATOM   15495 C C   . LEU E 1 378 ? 51.078  -41.344 61.249  1.00 32.38  ? 378 LEU E C   1 
ATOM   15496 O O   . LEU E 1 378 ? 50.204  -41.059 62.077  1.00 32.47  ? 378 LEU E O   1 
ATOM   15497 C CB  . LEU E 1 378 ? 51.817  -39.684 59.499  1.00 30.41  ? 378 LEU E CB  1 
ATOM   15498 C CG  . LEU E 1 378 ? 50.459  -39.004 59.423  1.00 26.35  ? 378 LEU E CG  1 
ATOM   15499 C CD1 . LEU E 1 378 ? 50.335  -37.935 60.505  1.00 25.64  ? 378 LEU E CD1 1 
ATOM   15500 C CD2 . LEU E 1 378 ? 50.247  -38.439 58.053  1.00 28.93  ? 378 LEU E CD2 1 
ATOM   15501 N N   . ALA E 1 379 ? 51.156  -42.558 60.694  1.00 27.88  ? 379 ALA E N   1 
ATOM   15502 C CA  . ALA E 1 379 ? 50.194  -43.602 61.049  1.00 34.77  ? 379 ALA E CA  1 
ATOM   15503 C C   . ALA E 1 379 ? 50.198  -43.908 62.552  1.00 34.45  ? 379 ALA E C   1 
ATOM   15504 O O   . ALA E 1 379 ? 49.133  -44.058 63.165  1.00 32.56  ? 379 ALA E O   1 
ATOM   15505 C CB  . ALA E 1 379 ? 50.486  -44.873 60.251  1.00 30.79  ? 379 ALA E CB  1 
ATOM   15506 N N   . ASP E 1 380 ? 51.383  -44.023 63.157  1.00 30.16  ? 380 ASP E N   1 
ATOM   15507 C CA  . ASP E 1 380 ? 51.463  -44.297 64.593  1.00 32.06  ? 380 ASP E CA  1 
ATOM   15508 C C   . ASP E 1 380 ? 50.950  -43.131 65.420  1.00 29.02  ? 380 ASP E C   1 
ATOM   15509 O O   . ASP E 1 380 ? 50.290  -43.343 66.442  1.00 36.67  ? 380 ASP E O   1 
ATOM   15510 C CB  . ASP E 1 380 ? 52.900  -44.634 64.989  1.00 30.10  ? 380 ASP E CB  1 
ATOM   15511 C CG  . ASP E 1 380 ? 53.455  -45.780 64.189  1.00 37.72  ? 380 ASP E CG  1 
ATOM   15512 O OD1 . ASP E 1 380 ? 52.789  -46.842 64.164  1.00 38.07  ? 380 ASP E OD1 1 
ATOM   15513 O OD2 . ASP E 1 380 ? 54.524  -45.611 63.564  1.00 39.69  ? 380 ASP E OD2 1 
ATOM   15514 N N   . LEU E 1 381 ? 51.238  -41.895 64.998  1.00 26.80  ? 381 LEU E N   1 
ATOM   15515 C CA  . LEU E 1 381 ? 50.770  -40.724 65.738  1.00 28.54  ? 381 LEU E CA  1 
ATOM   15516 C C   . LEU E 1 381 ? 49.244  -40.624 65.737  1.00 31.19  ? 381 LEU E C   1 
ATOM   15517 O O   . LEU E 1 381 ? 48.627  -40.446 66.796  1.00 29.26  ? 381 LEU E O   1 
ATOM   15518 C CB  . LEU E 1 381 ? 51.392  -39.445 65.160  1.00 26.76  ? 381 LEU E CB  1 
ATOM   15519 C CG  . LEU E 1 381 ? 52.897  -39.188 65.328  1.00 32.62  ? 381 LEU E CG  1 
ATOM   15520 C CD1 . LEU E 1 381 ? 53.303  -37.906 64.613  1.00 36.72  ? 381 LEU E CD1 1 
ATOM   15521 C CD2 . LEU E 1 381 ? 53.279  -39.094 66.806  1.00 31.98  ? 381 LEU E CD2 1 
ATOM   15522 N N   . LEU E 1 382 ? 48.617  -40.703 64.553  1.00 27.21  ? 382 LEU E N   1 
ATOM   15523 C CA  . LEU E 1 382 ? 47.161  -40.552 64.475  1.00 35.47  ? 382 LEU E CA  1 
ATOM   15524 C C   . LEU E 1 382 ? 46.456  -41.617 65.306  1.00 32.26  ? 382 LEU E C   1 
ATOM   15525 O O   . LEU E 1 382 ? 45.416  -41.361 65.914  1.00 34.50  ? 382 LEU E O   1 
ATOM   15526 C CB  . LEU E 1 382 ? 46.703  -40.621 63.016  1.00 25.81  ? 382 LEU E CB  1 
ATOM   15527 C CG  . LEU E 1 382 ? 47.142  -39.397 62.219  1.00 33.22  ? 382 LEU E CG  1 
ATOM   15528 C CD1 . LEU E 1 382 ? 46.817  -39.530 60.718  1.00 26.70  ? 382 LEU E CD1 1 
ATOM   15529 C CD2 . LEU E 1 382 ? 46.557  -38.108 62.827  1.00 25.17  ? 382 LEU E CD2 1 
ATOM   15530 N N   . ARG E 1 383 ? 47.026  -42.809 65.360  1.00 33.76  ? 383 ARG E N   1 
ATOM   15531 C CA  . ARG E 1 383 ? 46.553  -43.836 66.283  1.00 36.28  ? 383 ARG E CA  1 
ATOM   15532 C C   . ARG E 1 383 ? 46.467  -43.405 67.718  1.00 37.85  ? 383 ARG E C   1 
ATOM   15533 O O   . ARG E 1 383 ? 45.441  -43.626 68.372  1.00 35.41  ? 383 ARG E O   1 
ATOM   15534 C CB  . ARG E 1 383 ? 47.497  -44.960 66.342  1.00 43.41  ? 383 ARG E CB  1 
ATOM   15535 C CG  . ARG E 1 383 ? 46.827  -46.135 66.761  1.00 48.82  ? 383 ARG E CG  1 
ATOM   15536 C CD  . ARG E 1 383 ? 47.398  -46.631 65.654  1.00 46.75  ? 383 ARG E CD  1 
ATOM   15537 N NE  . ARG E 1 383 ? 47.323  -47.995 65.265  1.00 55.72  ? 383 ARG E NE  1 
ATOM   15538 C CZ  . ARG E 1 383 ? 47.688  -48.281 64.041  1.00 55.65  ? 383 ARG E CZ  1 
ATOM   15539 N NH1 . ARG E 1 383 ? 47.858  -47.320 63.147  1.00 54.04  ? 383 ARG E NH1 1 
ATOM   15540 N NH2 . ARG E 1 383 ? 47.934  -49.527 63.731  1.00 45.71  ? 383 ARG E NH2 1 
ATOM   15541 N N   . SER E 1 384 ? 47.634  -43.083 68.288  1.00 34.86  ? 384 SER E N   1 
ATOM   15542 C CA  . SER E 1 384 ? 47.703  -42.735 69.696  1.00 32.11  ? 384 SER E CA  1 
ATOM   15543 C C   . SER E 1 384 ? 46.675  -41.672 70.020  1.00 31.47  ? 384 SER E C   1 
ATOM   15544 O O   . SER E 1 384 ? 46.103  -41.668 71.115  1.00 33.88  ? 384 SER E O   1 
ATOM   15545 C CB  . SER E 1 384 ? 49.113  -42.255 70.027  1.00 32.76  ? 384 SER E CB  1 
ATOM   15546 O OG  . SER E 1 384 ? 50.072  -43.061 69.355  1.00 35.17  ? 384 SER E OG  1 
ATOM   15547 N N   . LEU E 1 385 ? 46.420  -40.775 69.065  1.00 29.99  ? 385 LEU E N   1 
ATOM   15548 C CA  . LEU E 1 385 ? 45.312  -39.836 69.180  1.00 31.54  ? 385 LEU E CA  1 
ATOM   15549 C C   . LEU E 1 385 ? 43.982  -40.569 69.296  1.00 29.77  ? 385 LEU E C   1 
ATOM   15550 O O   . LEU E 1 385 ? 43.096  -40.147 70.046  1.00 32.94  ? 385 LEU E O   1 
ATOM   15551 C CB  . LEU E 1 385 ? 45.307  -38.907 67.962  1.00 28.74  ? 385 LEU E CB  1 
ATOM   15552 C CG  . LEU E 1 385 ? 46.542  -38.011 67.828  1.00 34.59  ? 385 LEU E CG  1 
ATOM   15553 C CD1 . LEU E 1 385 ? 46.395  -36.979 66.688  1.00 29.62  ? 385 LEU E CD1 1 
ATOM   15554 C CD2 . LEU E 1 385 ? 46.808  -37.333 69.152  1.00 30.89  ? 385 LEU E CD2 1 
ATOM   15555 N N   . GLU E 1 386 ? 43.810  -41.642 68.520  1.00 27.70  ? 386 GLU E N   1 
ATOM   15556 C CA  . GLU E 1 386 ? 42.577  -42.426 68.558  1.00 30.84  ? 386 GLU E CA  1 
ATOM   15557 C C   . GLU E 1 386 ? 42.504  -43.266 69.832  1.00 32.77  ? 386 GLU E C   1 
ATOM   15558 O O   . GLU E 1 386 ? 41.479  -43.277 70.529  1.00 30.74  ? 386 GLU E O   1 
ATOM   15559 C CB  . GLU E 1 386 ? 42.492  -43.307 67.304  1.00 25.78  ? 386 GLU E CB  1 
ATOM   15560 C CG  . GLU E 1 386 ? 41.944  -42.594 66.069  1.00 26.76  ? 386 GLU E CG  1 
ATOM   15561 C CD  . GLU E 1 386 ? 41.726  -43.527 64.881  1.00 35.78  ? 386 GLU E CD  1 
ATOM   15562 O OE1 . GLU E 1 386 ? 40.867  -44.443 64.973  1.00 34.54  ? 386 GLU E OE1 1 
ATOM   15563 O OE2 . GLU E 1 386 ? 42.390  -43.309 63.835  1.00 30.35  ? 386 GLU E OE2 1 
ATOM   15564 N N   . ARG E 1 387 ? 43.592  -43.973 70.159  1.00 26.43  ? 387 ARG E N   1 
ATOM   15565 C CA  . ARG E 1 387 ? 43.653  -44.683 71.430  1.00 33.63  ? 387 ARG E CA  1 
ATOM   15566 C C   . ARG E 1 387 ? 43.349  -43.750 72.610  1.00 34.29  ? 387 ARG E C   1 
ATOM   15567 O O   . ARG E 1 387 ? 42.760  -44.181 73.606  1.00 33.48  ? 387 ARG E O   1 
ATOM   15568 C CB  . ARG E 1 387 ? 45.029  -45.352 71.572  1.00 34.04  ? 387 ARG E CB  1 
ATOM   15569 C CG  . ARG E 1 387 ? 45.315  -46.034 72.927  1.00 39.61  ? 387 ARG E CG  1 
ATOM   15570 C CD  . ARG E 1 387 ? 46.750  -46.628 72.986  1.00 35.25  ? 387 ARG E CD  1 
ATOM   15571 N NE  . ARG E 1 387 ? 47.259  -46.948 71.660  1.00 37.36  ? 387 ARG E NE  1 
ATOM   15572 C CZ  . ARG E 1 387 ? 48.294  -46.354 71.079  1.00 39.40  ? 387 ARG E CZ  1 
ATOM   15573 N NH1 . ARG E 1 387 ? 49.032  -45.463 71.721  1.00 36.83  ? 387 ARG E NH1 1 
ATOM   15574 N NH2 . ARG E 1 387 ? 48.583  -46.645 69.813  1.00 37.99  ? 387 ARG E NH2 1 
ATOM   15575 N N   . ALA E 1 388 ? 43.699  -42.463 72.507  1.00 31.22  ? 388 ALA E N   1 
ATOM   15576 C CA  . ALA E 1 388 ? 43.377  -41.540 73.594  1.00 33.25  ? 388 ALA E CA  1 
ATOM   15577 C C   . ALA E 1 388 ? 41.972  -40.974 73.494  1.00 30.55  ? 388 ALA E C   1 
ATOM   15578 O O   . ALA E 1 388 ? 41.482  -40.404 74.471  1.00 33.00  ? 388 ALA E O   1 
ATOM   15579 C CB  . ALA E 1 388 ? 44.379  -40.382 73.640  1.00 38.25  ? 388 ALA E CB  1 
ATOM   15580 N N   . GLY E 1 389 ? 41.319  -41.117 72.346  1.00 33.70  ? 389 GLY E N   1 
ATOM   15581 C CA  . GLY E 1 389 ? 40.010  -40.530 72.140  1.00 33.55  ? 389 GLY E CA  1 
ATOM   15582 C C   . GLY E 1 389 ? 39.983  -39.048 71.816  1.00 36.43  ? 389 GLY E C   1 
ATOM   15583 O O   . GLY E 1 389 ? 38.946  -38.409 72.030  1.00 35.00  ? 389 GLY E O   1 
ATOM   15584 N N   . VAL E 1 390 ? 41.079  -38.465 71.304  1.00 32.23  ? 390 VAL E N   1 
ATOM   15585 C CA  . VAL E 1 390 ? 41.090  -37.019 71.061  1.00 29.37  ? 390 VAL E CA  1 
ATOM   15586 C C   . VAL E 1 390 ? 41.553  -36.647 69.655  1.00 31.59  ? 390 VAL E C   1 
ATOM   15587 O O   . VAL E 1 390 ? 41.759  -35.462 69.379  1.00 33.50  ? 390 VAL E O   1 
ATOM   15588 C CB  . VAL E 1 390 ? 41.951  -36.258 72.099  1.00 27.61  ? 390 VAL E CB  1 
ATOM   15589 C CG1 . VAL E 1 390 ? 41.710  -36.761 73.508  1.00 31.88  ? 390 VAL E CG1 1 
ATOM   15590 C CG2 . VAL E 1 390 ? 43.408  -36.352 71.774  1.00 27.76  ? 390 VAL E CG2 1 
ATOM   15591 N N   . ARG E 1 391 ? 41.725  -37.619 68.754  1.00 29.24  ? 391 ARG E N   1 
ATOM   15592 C CA  . ARG E 1 391 ? 41.987  -37.272 67.360  1.00 29.01  ? 391 ARG E CA  1 
ATOM   15593 C C   . ARG E 1 391 ? 40.929  -36.284 66.876  1.00 29.39  ? 391 ARG E C   1 
ATOM   15594 O O   . ARG E 1 391 ? 39.759  -36.378 67.260  1.00 29.34  ? 391 ARG E O   1 
ATOM   15595 C CB  . ARG E 1 391 ? 41.990  -38.528 66.478  1.00 25.43  ? 391 ARG E CB  1 
ATOM   15596 C CG  . ARG E 1 391 ? 41.886  -38.218 64.988  1.00 28.52  ? 391 ARG E CG  1 
ATOM   15597 C CD  . ARG E 1 391 ? 42.413  -39.348 64.064  1.00 23.65  ? 391 ARG E CD  1 
ATOM   15598 N NE  . ARG E 1 391 ? 42.505  -38.880 62.684  1.00 25.51  ? 391 ARG E NE  1 
ATOM   15599 C CZ  . ARG E 1 391 ? 42.747  -39.652 61.633  1.00 28.66  ? 391 ARG E CZ  1 
ATOM   15600 N NH1 . ARG E 1 391 ? 42.919  -40.955 61.754  1.00 24.46  ? 391 ARG E NH1 1 
ATOM   15601 N NH2 . ARG E 1 391 ? 42.824  -39.099 60.426  1.00 31.01  ? 391 ARG E NH2 1 
ATOM   15602 N N   . TYR E 1 392 ? 41.339  -35.300 66.067  1.00 29.54  ? 392 TYR E N   1 
ATOM   15603 C CA  . TYR E 1 392 ? 40.427  -34.192 65.756  1.00 28.58  ? 392 TYR E CA  1 
ATOM   15604 C C   . TYR E 1 392 ? 39.220  -34.679 64.966  1.00 26.87  ? 392 TYR E C   1 
ATOM   15605 O O   . TYR E 1 392 ? 39.361  -35.317 63.918  1.00 25.02  ? 392 TYR E O   1 
ATOM   15606 C CB  . TYR E 1 392 ? 41.123  -33.080 64.970  1.00 25.11  ? 392 TYR E CB  1 
ATOM   15607 C CG  . TYR E 1 392 ? 40.174  -31.952 64.581  1.00 27.02  ? 392 TYR E CG  1 
ATOM   15608 C CD1 . TYR E 1 392 ? 39.835  -30.955 65.488  1.00 27.51  ? 392 TYR E CD1 1 
ATOM   15609 C CD2 . TYR E 1 392 ? 39.600  -31.901 63.330  1.00 27.20  ? 392 TYR E CD2 1 
ATOM   15610 C CE1 . TYR E 1 392 ? 38.969  -29.940 65.146  1.00 28.44  ? 392 TYR E CE1 1 
ATOM   15611 C CE2 . TYR E 1 392 ? 38.724  -30.878 62.978  1.00 27.21  ? 392 TYR E CE2 1 
ATOM   15612 C CZ  . TYR E 1 392 ? 38.418  -29.902 63.891  1.00 29.21  ? 392 TYR E CZ  1 
ATOM   15613 O OH  . TYR E 1 392 ? 37.556  -28.883 63.555  1.00 32.09  ? 392 TYR E OH  1 
ATOM   15614 N N   . ASP E 1 393 ? 38.032  -34.305 65.448  1.00 36.48  ? 393 ASP E N   1 
ATOM   15615 C CA  . ASP E 1 393 ? 36.744  -34.778 64.948  1.00 30.46  ? 393 ASP E CA  1 
ATOM   15616 C C   . ASP E 1 393 ? 35.989  -33.591 64.362  1.00 30.75  ? 393 ASP E C   1 
ATOM   15617 O O   . ASP E 1 393 ? 35.694  -32.626 65.080  1.00 30.69  ? 393 ASP E O   1 
ATOM   15618 C CB  . ASP E 1 393 ? 35.962  -35.447 66.086  1.00 27.31  ? 393 ASP E CB  1 
ATOM   15619 C CG  . ASP E 1 393 ? 34.476  -35.643 65.779  1.00 32.67  ? 393 ASP E CG  1 
ATOM   15620 O OD1 . ASP E 1 393 ? 34.096  -35.973 64.639  1.00 34.87  ? 393 ASP E OD1 1 
ATOM   15621 O OD2 . ASP E 1 393 ? 33.676  -35.475 66.715  1.00 41.42  ? 393 ASP E OD2 1 
ATOM   15622 N N   . LYS E 1 394 ? 35.703  -33.661 63.056  1.00 26.46  ? 394 LYS E N   1 
ATOM   15623 C CA  . LYS E 1 394 ? 34.908  -32.645 62.362  1.00 35.11  ? 394 LYS E CA  1 
ATOM   15624 C C   . LYS E 1 394 ? 33.706  -32.178 63.180  1.00 37.23  ? 394 LYS E C   1 
ATOM   15625 O O   . LYS E 1 394 ? 33.473  -30.979 63.342  1.00 41.52  ? 394 LYS E O   1 
ATOM   15626 C CB  . LYS E 1 394 ? 34.398  -33.203 61.024  1.00 39.14  ? 394 LYS E CB  1 
ATOM   15627 C CG  . LYS E 1 394 ? 35.441  -33.693 60.045  1.00 44.92  ? 394 LYS E CG  1 
ATOM   15628 C CD  . LYS E 1 394 ? 34.786  -34.001 58.689  1.00 51.93  ? 394 LYS E CD  1 
ATOM   15629 C CE  . LYS E 1 394 ? 35.803  -34.512 57.654  1.00 52.99  ? 394 LYS E CE  1 
ATOM   15630 N NZ  . LYS E 1 394 ? 36.943  -33.563 57.397  1.00 51.59  ? 394 LYS E NZ  1 
ATOM   15631 N N   . ASP E 1 395 ? 32.928  -33.124 63.702  1.00 38.10  ? 395 ASP E N   1 
ATOM   15632 C CA  . ASP E 1 395 ? 31.582  -32.808 64.160  1.00 39.95  ? 395 ASP E CA  1 
ATOM   15633 C C   . ASP E 1 395 ? 31.553  -32.186 65.550  1.00 39.57  ? 395 ASP E C   1 
ATOM   15634 O O   . ASP E 1 395 ? 30.535  -31.597 65.930  1.00 35.50  ? 395 ASP E O   1 
ATOM   15635 C CB  . ASP E 1 395 ? 30.708  -34.064 64.104  1.00 36.59  ? 395 ASP E CB  1 
ATOM   15636 C CG  . ASP E 1 395 ? 30.226  -34.373 62.681  1.00 43.23  ? 395 ASP E CG  1 
ATOM   15637 O OD1 . ASP E 1 395 ? 30.966  -35.026 61.909  1.00 41.68  ? 395 ASP E OD1 1 
ATOM   15638 O OD2 . ASP E 1 395 ? 29.115  -33.922 62.320  1.00 51.53  ? 395 ASP E OD2 1 
ATOM   15639 N N   . SER E 1 396 ? 32.643  -32.274 66.304  1.00 36.45  ? 396 SER E N   1 
ATOM   15640 C CA  . SER E 1 396 ? 32.739  -31.567 67.572  1.00 31.21  ? 396 SER E CA  1 
ATOM   15641 C C   . SER E 1 396 ? 33.602  -30.317 67.489  1.00 35.54  ? 396 SER E C   1 
ATOM   15642 O O   . SER E 1 396 ? 33.406  -29.387 68.277  1.00 34.50  ? 396 SER E O   1 
ATOM   15643 C CB  . SER E 1 396 ? 33.323  -32.485 68.643  1.00 26.71  ? 396 SER E CB  1 
ATOM   15644 O OG  . SER E 1 396 ? 34.714  -32.636 68.405  1.00 34.14  ? 396 SER E OG  1 
ATOM   15645 N N   . GLY E 1 397 ? 34.551  -30.269 66.558  1.00 35.66  ? 397 GLY E N   1 
ATOM   15646 C CA  . GLY E 1 397 ? 35.543  -29.216 66.583  1.00 29.99  ? 397 GLY E CA  1 
ATOM   15647 C C   . GLY E 1 397 ? 36.578  -29.364 67.675  1.00 34.00  ? 397 GLY E C   1 
ATOM   15648 O O   . GLY E 1 397 ? 37.257  -28.386 67.993  1.00 38.43  ? 397 GLY E O   1 
ATOM   15649 N N   . GLU E 1 398 ? 36.718  -30.561 68.260  1.00 30.88  ? 398 GLU E N   1 
ATOM   15650 C CA  . GLU E 1 398 ? 37.568  -30.813 69.419  1.00 28.66  ? 398 GLU E CA  1 
ATOM   15651 C C   . GLU E 1 398 ? 38.597  -31.892 69.091  1.00 25.71  ? 398 GLU E C   1 
ATOM   15652 O O   . GLU E 1 398 ? 38.316  -32.833 68.348  1.00 25.94  ? 398 GLU E O   1 
ATOM   15653 C CB  . GLU E 1 398 ? 36.759  -31.273 70.654  1.00 32.24  ? 398 GLU E CB  1 
ATOM   15654 C CG  . GLU E 1 398 ? 35.532  -30.433 71.001  1.00 35.39  ? 398 GLU E CG  1 
ATOM   15655 C CD  . GLU E 1 398 ? 35.626  -29.812 72.393  1.00 36.44  ? 398 GLU E CD  1 
ATOM   15656 O OE1 . GLU E 1 398 ? 36.277  -30.410 73.268  1.00 43.17  ? 398 GLU E OE1 1 
ATOM   15657 O OE2 . GLU E 1 398 ? 35.044  -28.729 72.621  1.00 41.29  ? 398 GLU E OE2 1 
ATOM   15658 N N   . GLY E 1 399 ? 39.787  -31.747 69.651  1.00 23.59  ? 399 GLY E N   1 
ATOM   15659 C CA  . GLY E 1 399 ? 40.828  -32.722 69.466  1.00 25.40  ? 399 GLY E CA  1 
ATOM   15660 C C   . GLY E 1 399 ? 42.072  -32.190 68.787  1.00 25.82  ? 399 GLY E C   1 
ATOM   15661 O O   . GLY E 1 399 ? 42.259  -30.981 68.637  1.00 23.35  ? 399 GLY E O   1 
ATOM   15662 N N   . ALA E 1 400 ? 42.926  -33.110 68.358  1.00 26.60  ? 400 ALA E N   1 
ATOM   15663 C CA  . ALA E 1 400 ? 44.301  -32.809 68.027  1.00 24.81  ? 400 ALA E CA  1 
ATOM   15664 C C   . ALA E 1 400 ? 44.568  -33.101 66.561  1.00 27.72  ? 400 ALA E C   1 
ATOM   15665 O O   . ALA E 1 400 ? 44.003  -34.037 65.977  1.00 27.91  ? 400 ALA E O   1 
ATOM   15666 C CB  . ALA E 1 400 ? 45.266  -33.615 68.910  1.00 26.24  ? 400 ALA E CB  1 
ATOM   15667 N N   . VAL E 1 401 ? 45.445  -32.283 65.983  1.00 25.52  ? 401 VAL E N   1 
ATOM   15668 C CA  . VAL E 1 401 ? 45.921  -32.451 64.622  1.00 23.05  ? 401 VAL E CA  1 
ATOM   15669 C C   . VAL E 1 401 ? 47.439  -32.413 64.648  1.00 25.79  ? 401 VAL E C   1 
ATOM   15670 O O   . VAL E 1 401 ? 48.046  -31.769 65.511  1.00 22.93  ? 401 VAL E O   1 
ATOM   15671 C CB  . VAL E 1 401 ? 45.364  -31.367 63.696  1.00 26.59  ? 401 VAL E CB  1 
ATOM   15672 C CG1 . VAL E 1 401 ? 43.867  -31.469 63.627  1.00 19.66  ? 401 VAL E CG1 1 
ATOM   15673 C CG2 . VAL E 1 401 ? 45.785  -29.990 64.199  1.00 26.39  ? 401 VAL E CG2 1 
ATOM   15674 N N   . VAL E 1 402 ? 48.049  -33.140 63.711  1.00 20.93  ? 402 VAL E N   1 
ATOM   15675 C CA  . VAL E 1 402 ? 49.494  -33.301 63.653  1.00 25.60  ? 402 VAL E CA  1 
ATOM   15676 C C   . VAL E 1 402 ? 50.080  -32.267 62.702  1.00 30.78  ? 402 VAL E C   1 
ATOM   15677 O O   . VAL E 1 402 ? 49.686  -32.180 61.532  1.00 28.21  ? 402 VAL E O   1 
ATOM   15678 C CB  . VAL E 1 402 ? 49.872  -34.719 63.196  1.00 30.92  ? 402 VAL E CB  1 
ATOM   15679 C CG1 . VAL E 1 402 ? 51.361  -34.968 63.420  1.00 27.76  ? 402 VAL E CG1 1 
ATOM   15680 C CG2 . VAL E 1 402 ? 49.037  -35.749 63.915  1.00 29.06  ? 402 VAL E CG2 1 
ATOM   15681 N N   . LEU E 1 403 ? 51.038  -31.494 63.194  1.00 28.37  ? 403 LEU E N   1 
ATOM   15682 C CA  . LEU E 1 403 ? 51.782  -30.593 62.338  1.00 22.61  ? 403 LEU E CA  1 
ATOM   15683 C C   . LEU E 1 403 ? 53.167  -31.124 62.008  1.00 29.95  ? 403 LEU E C   1 
ATOM   15684 O O   . LEU E 1 403 ? 53.797  -30.626 61.068  1.00 34.07  ? 403 LEU E O   1 
ATOM   15685 C CB  . LEU E 1 403 ? 51.889  -29.223 63.003  1.00 23.61  ? 403 LEU E CB  1 
ATOM   15686 C CG  . LEU E 1 403 ? 50.726  -28.263 62.717  1.00 27.43  ? 403 LEU E CG  1 
ATOM   15687 C CD1 . LEU E 1 403 ? 49.336  -28.834 63.098  1.00 22.98  ? 403 LEU E CD1 1 
ATOM   15688 C CD2 . LEU E 1 403 ? 50.963  -26.972 63.452  1.00 28.30  ? 403 LEU E CD2 1 
ATOM   15689 N N   . GLY E 1 404 ? 53.645  -32.127 62.742  1.00 28.77  ? 404 GLY E N   1 
ATOM   15690 C CA  . GLY E 1 404 ? 54.970  -32.671 62.516  1.00 31.93  ? 404 GLY E CA  1 
ATOM   15691 C C   . GLY E 1 404 ? 55.191  -34.024 63.162  1.00 37.34  ? 404 GLY E C   1 
ATOM   15692 O O   . GLY E 1 404 ? 54.856  -34.256 64.334  1.00 33.58  ? 404 GLY E O   1 
ATOM   15693 N N   . CYS E 1 405 ? 55.764  -34.940 62.398  1.00 29.61  ? 405 CYS E N   1 
ATOM   15694 C CA  . CYS E 1 405 ? 56.028  -36.249 62.963  1.00 37.30  ? 405 CYS E CA  1 
ATOM   15695 C C   . CYS E 1 405 ? 57.329  -36.285 63.749  1.00 36.91  ? 405 CYS E C   1 
ATOM   15696 O O   . CYS E 1 405 ? 57.457  -37.089 64.678  1.00 32.77  ? 405 CYS E O   1 
ATOM   15697 C CB  . CYS E 1 405 ? 56.036  -37.278 61.841  1.00 40.83  ? 405 CYS E CB  1 
ATOM   15698 S SG  . CYS E 1 405 ? 54.437  -37.316 60.995  1.00 34.88  ? 405 CYS E SG  1 
ATOM   15699 N N   . ASN E 1 406 ? 58.279  -35.407 63.413  1.00 35.60  ? 406 ASN E N   1 
ATOM   15700 C CA  . ASN E 1 406 ? 59.641  -35.471 63.932  1.00 38.03  ? 406 ASN E CA  1 
ATOM   15701 C C   . ASN E 1 406 ? 60.344  -34.144 63.661  1.00 40.18  ? 406 ASN E C   1 
ATOM   15702 O O   . ASN E 1 406 ? 61.184  -34.038 62.764  1.00 38.12  ? 406 ASN E O   1 
ATOM   15703 C CB  . ASN E 1 406 ? 60.393  -36.631 63.284  1.00 34.47  ? 406 ASN E CB  1 
ATOM   15704 C CG  . ASN E 1 406 ? 61.791  -36.792 63.821  1.00 42.34  ? 406 ASN E CG  1 
ATOM   15705 O OD1 . ASN E 1 406 ? 62.058  -36.524 64.990  1.00 40.81  ? 406 ASN E OD1 1 
ATOM   15706 N ND2 . ASN E 1 406 ? 62.694  -37.249 62.970  1.00 45.19  ? 406 ASN E ND2 1 
ATOM   15707 N N   . SER E 1 407 ? 59.958  -33.112 64.392  1.00 36.78  ? 407 SER E N   1 
ATOM   15708 C CA  . SER E 1 407 ? 60.423  -31.763 64.137  1.00 40.65  ? 407 SER E CA  1 
ATOM   15709 C C   . SER E 1 407 ? 61.459  -31.389 65.184  1.00 37.69  ? 407 SER E C   1 
ATOM   15710 O O   . SER E 1 407 ? 61.449  -31.908 66.302  1.00 37.50  ? 407 SER E O   1 
ATOM   15711 C CB  . SER E 1 407 ? 59.247  -30.776 64.150  1.00 34.29  ? 407 SER E CB  1 
ATOM   15712 O OG  . SER E 1 407 ? 59.667  -29.432 64.299  1.00 35.24  ? 407 SER E OG  1 
ATOM   15713 N N   . ASP E 1 408 ? 62.369  -30.501 64.825  1.00 40.58  ? 408 ASP E N   1 
ATOM   15714 C CA  . ASP E 1 408 ? 63.301  -30.033 65.837  1.00 41.64  ? 408 ASP E CA  1 
ATOM   15715 C C   . ASP E 1 408 ? 62.753  -28.859 66.647  1.00 42.43  ? 408 ASP E C   1 
ATOM   15716 O O   . ASP E 1 408 ? 63.435  -28.400 67.573  1.00 33.96  ? 408 ASP E O   1 
ATOM   15717 C CB  . ASP E 1 408 ? 64.655  -29.718 65.192  1.00 40.74  ? 408 ASP E CB  1 
ATOM   15718 C CG  . ASP E 1 408 ? 64.577  -28.615 64.153  1.00 53.61  ? 408 ASP E CG  1 
ATOM   15719 O OD1 . ASP E 1 408 ? 64.421  -27.431 64.531  1.00 56.32  ? 408 ASP E OD1 1 
ATOM   15720 O OD2 . ASP E 1 408 ? 64.687  -28.942 62.943  1.00 53.21  ? 408 ASP E OD2 1 
ATOM   15721 N N   . LEU E 1 409 ? 61.515  -28.420 66.362  1.00 34.29  ? 409 LEU E N   1 
ATOM   15722 C CA  . LEU E 1 409 ? 60.905  -27.304 67.087  1.00 39.33  ? 409 LEU E CA  1 
ATOM   15723 C C   . LEU E 1 409 ? 60.983  -27.496 68.593  1.00 38.10  ? 409 LEU E C   1 
ATOM   15724 O O   . LEU E 1 409 ? 61.424  -26.607 69.328  1.00 45.09  ? 409 LEU E O   1 
ATOM   15725 C CB  . LEU E 1 409 ? 59.442  -27.143 66.680  1.00 41.08  ? 409 LEU E CB  1 
ATOM   15726 C CG  . LEU E 1 409 ? 59.119  -26.179 65.541  1.00 43.70  ? 409 LEU E CG  1 
ATOM   15727 C CD1 . LEU E 1 409 ? 57.691  -25.649 65.680  1.00 37.11  ? 409 LEU E CD1 1 
ATOM   15728 C CD2 . LEU E 1 409 ? 60.122  -25.049 65.515  1.00 43.63  ? 409 LEU E CD2 1 
ATOM   15729 N N   . GLY E 1 410 ? 60.506  -28.627 69.075  1.00 37.34  ? 410 GLY E N   1 
ATOM   15730 C CA  . GLY E 1 410 ? 60.668  -28.986 70.461  1.00 43.65  ? 410 GLY E CA  1 
ATOM   15731 C C   . GLY E 1 410 ? 61.153  -30.414 70.528  1.00 49.27  ? 410 GLY E C   1 
ATOM   15732 O O   . GLY E 1 410 ? 60.423  -31.324 70.935  1.00 52.90  ? 410 GLY E O   1 
ATOM   15733 N N   . PRO E 1 411 ? 62.431  -30.614 70.208  1.00 47.97  ? 411 PRO E N   1 
ATOM   15734 C CA  . PRO E 1 411 ? 62.864  -31.843 69.525  1.00 43.48  ? 411 PRO E CA  1 
ATOM   15735 C C   . PRO E 1 411 ? 61.884  -33.000 69.621  1.00 51.03  ? 411 PRO E C   1 
ATOM   15736 O O   . PRO E 1 411 ? 62.154  -33.988 70.311  1.00 61.76  ? 411 PRO E O   1 
ATOM   15737 C CB  . PRO E 1 411 ? 64.185  -32.172 70.221  1.00 41.56  ? 411 PRO E CB  1 
ATOM   15738 C CG  . PRO E 1 411 ? 64.719  -30.849 70.629  1.00 39.21  ? 411 PRO E CG  1 
ATOM   15739 C CD  . PRO E 1 411 ? 63.546  -29.939 70.890  1.00 46.53  ? 411 PRO E CD  1 
ATOM   15740 N N   . GLY E 1 412 ? 60.738  -32.885 68.964  1.00 41.34  ? 412 GLY E N   1 
ATOM   15741 C CA  . GLY E 1 412 ? 59.782  -33.968 68.956  1.00 41.17  ? 412 GLY E CA  1 
ATOM   15742 C C   . GLY E 1 412 ? 58.747  -33.847 67.848  1.00 37.25  ? 412 GLY E C   1 
ATOM   15743 O O   . GLY E 1 412 ? 58.949  -33.149 66.853  1.00 29.40  ? 412 GLY E O   1 
ATOM   15744 N N   . ALA E 1 413 ? 57.643  -34.570 68.027  1.00 35.10  ? 413 ALA E N   1 
ATOM   15745 C CA  . ALA E 1 413 ? 56.480  -34.446 67.164  1.00 35.41  ? 413 ALA E CA  1 
ATOM   15746 C C   . ALA E 1 413 ? 55.594  -33.334 67.695  1.00 29.99  ? 413 ALA E C   1 
ATOM   15747 O O   . ALA E 1 413 ? 55.498  -33.127 68.904  1.00 31.79  ? 413 ALA E O   1 
ATOM   15748 C CB  . ALA E 1 413 ? 55.690  -35.753 67.103  1.00 33.72  ? 413 ALA E CB  1 
ATOM   15749 N N   . GLU E 1 414 ? 54.964  -32.608 66.777  1.00 27.45  ? 414 GLU E N   1 
ATOM   15750 C CA  . GLU E 1 414 ? 54.228  -31.389 67.082  1.00 31.38  ? 414 GLU E CA  1 
ATOM   15751 C C   . GLU E 1 414 ? 52.741  -31.643 66.893  1.00 24.44  ? 414 GLU E C   1 
ATOM   15752 O O   . GLU E 1 414 ? 52.308  -32.017 65.805  1.00 26.07  ? 414 GLU E O   1 
ATOM   15753 C CB  . GLU E 1 414 ? 54.689  -30.227 66.187  1.00 32.37  ? 414 GLU E CB  1 
ATOM   15754 C CG  . GLU E 1 414 ? 53.895  -28.919 66.390  1.00 32.48  ? 414 GLU E CG  1 
ATOM   15755 C CD  . GLU E 1 414 ? 54.319  -27.750 65.461  1.00 34.31  ? 414 GLU E CD  1 
ATOM   15756 O OE1 . GLU E 1 414 ? 54.831  -28.003 64.345  1.00 29.86  ? 414 GLU E OE1 1 
ATOM   15757 O OE2 . GLU E 1 414 ? 54.095  -26.570 65.849  1.00 26.43  ? 414 GLU E OE2 1 
ATOM   15758 N N   . LEU E 1 415 ? 51.955  -31.394 67.927  1.00 27.37  ? 415 LEU E N   1 
ATOM   15759 C CA  . LEU E 1 415 ? 50.513  -31.521 67.829  1.00 26.74  ? 415 LEU E CA  1 
ATOM   15760 C C   . LEU E 1 415 ? 49.850  -30.196 68.200  1.00 28.11  ? 415 LEU E C   1 
ATOM   15761 O O   . LEU E 1 415 ? 50.353  -29.450 69.044  1.00 27.54  ? 415 LEU E O   1 
ATOM   15762 C CB  . LEU E 1 415 ? 49.991  -32.646 68.750  1.00 28.57  ? 415 LEU E CB  1 
ATOM   15763 C CG  . LEU E 1 415 ? 50.516  -34.085 68.615  1.00 32.76  ? 415 LEU E CG  1 
ATOM   15764 C CD1 . LEU E 1 415 ? 49.781  -34.983 69.598  1.00 30.15  ? 415 LEU E CD1 1 
ATOM   15765 C CD2 . LEU E 1 415 ? 50.347  -34.602 67.211  1.00 27.37  ? 415 LEU E CD2 1 
ATOM   15766 N N   . LEU E 1 416 ? 48.710  -29.911 67.570  1.00 26.00  ? 416 LEU E N   1 
ATOM   15767 C CA  . LEU E 1 416 ? 47.854  -28.786 67.938  1.00 23.36  ? 416 LEU E CA  1 
ATOM   15768 C C   . LEU E 1 416 ? 46.504  -29.334 68.387  1.00 23.95  ? 416 LEU E C   1 
ATOM   15769 O O   . LEU E 1 416 ? 45.916  -30.184 67.701  1.00 27.10  ? 416 LEU E O   1 
ATOM   15770 C CB  . LEU E 1 416 ? 47.696  -27.828 66.757  1.00 23.00  ? 416 LEU E CB  1 
ATOM   15771 C CG  . LEU E 1 416 ? 46.866  -26.548 66.910  1.00 26.14  ? 416 LEU E CG  1 
ATOM   15772 C CD1 . LEU E 1 416 ? 47.478  -25.644 67.969  1.00 28.43  ? 416 LEU E CD1 1 
ATOM   15773 C CD2 . LEU E 1 416 ? 46.731  -25.819 65.571  1.00 20.97  ? 416 LEU E CD2 1 
ATOM   15774 N N   . VAL E 1 417 ? 46.013  -28.853 69.529  1.00 23.56  ? 417 VAL E N   1 
ATOM   15775 C CA  . VAL E 1 417 ? 44.898  -29.472 70.243  1.00 25.62  ? 417 VAL E CA  1 
ATOM   15776 C C   . VAL E 1 417 ? 43.826  -28.425 70.525  1.00 27.04  ? 417 VAL E C   1 
ATOM   15777 O O   . VAL E 1 417 ? 44.128  -27.347 71.051  1.00 26.67  ? 417 VAL E O   1 
ATOM   15778 C CB  . VAL E 1 417 ? 45.366  -30.110 71.565  1.00 28.43  ? 417 VAL E CB  1 
ATOM   15779 C CG1 . VAL E 1 417 ? 44.218  -30.883 72.210  1.00 30.91  ? 417 VAL E CG1 1 
ATOM   15780 C CG2 . VAL E 1 417 ? 46.588  -31.005 71.336  1.00 27.07  ? 417 VAL E CG2 1 
ATOM   15781 N N   . PHE E 1 418 ? 42.573  -28.761 70.220  1.00 26.72  ? 418 PHE E N   1 
ATOM   15782 C CA  . PHE E 1 418 ? 41.464  -27.810 70.215  1.00 26.95  ? 418 PHE E CA  1 
ATOM   15783 C C   . PHE E 1 418 ? 40.399  -28.222 71.226  1.00 28.14  ? 418 PHE E C   1 
ATOM   15784 O O   . PHE E 1 418 ? 40.050  -29.405 71.301  1.00 29.63  ? 418 PHE E O   1 
ATOM   15785 C CB  . PHE E 1 418 ? 40.826  -27.745 68.828  1.00 26.33  ? 418 PHE E CB  1 
ATOM   15786 C CG  . PHE E 1 418 ? 41.673  -27.086 67.788  1.00 28.34  ? 418 PHE E CG  1 
ATOM   15787 C CD1 . PHE E 1 418 ? 41.721  -25.705 67.683  1.00 26.83  ? 418 PHE E CD1 1 
ATOM   15788 C CD2 . PHE E 1 418 ? 42.394  -27.845 66.879  1.00 27.75  ? 418 PHE E CD2 1 
ATOM   15789 C CE1 . PHE E 1 418 ? 42.498  -25.101 66.705  1.00 29.66  ? 418 PHE E CE1 1 
ATOM   15790 C CE2 . PHE E 1 418 ? 43.180  -27.230 65.884  1.00 23.29  ? 418 PHE E CE2 1 
ATOM   15791 C CZ  . PHE E 1 418 ? 43.231  -25.865 65.807  1.00 21.65  ? 418 PHE E CZ  1 
ATOM   15792 N N   . SER E 1 419 ? 39.856  -27.252 71.977  1.00 33.07  ? 419 SER E N   1 
ATOM   15793 C CA  . SER E 1 419 ? 38.700  -27.514 72.846  1.00 29.40  ? 419 SER E CA  1 
ATOM   15794 C C   . SER E 1 419 ? 37.908  -26.242 73.136  1.00 33.75  ? 419 SER E C   1 
ATOM   15795 O O   . SER E 1 419 ? 38.468  -25.144 73.208  1.00 34.80  ? 419 SER E O   1 
ATOM   15796 C CB  . SER E 1 419 ? 39.113  -28.132 74.176  1.00 31.66  ? 419 SER E CB  1 
ATOM   15797 O OG  . SER E 1 419 ? 37.962  -28.529 74.886  1.00 31.59  ? 419 SER E OG  1 
ATOM   15798 N N   . LYS E 1 420 ? 36.593  -26.406 73.330  1.00 36.63  ? 420 LYS E N   1 
ATOM   15799 C CA  . LYS E 1 420 ? 35.749  -25.288 73.748  1.00 34.27  ? 420 LYS E CA  1 
ATOM   15800 C C   . LYS E 1 420 ? 35.814  -25.012 75.246  1.00 34.95  ? 420 LYS E C   1 
ATOM   15801 O O   . LYS E 1 420 ? 35.240  -24.018 75.705  1.00 30.90  ? 420 LYS E O   1 
ATOM   15802 C CB  . LYS E 1 420 ? 34.290  -25.530 73.362  1.00 35.74  ? 420 LYS E CB  1 
ATOM   15803 C CG  . LYS E 1 420 ? 34.012  -25.581 71.864  1.00 37.32  ? 420 LYS E CG  1 
ATOM   15804 C CD  . LYS E 1 420 ? 32.785  -26.448 71.596  1.00 35.47  ? 420 LYS E CD  1 
ATOM   15805 C CE  . LYS E 1 420 ? 32.413  -26.460 70.141  1.00 42.26  ? 420 LYS E CE  1 
ATOM   15806 N NZ  . LYS E 1 420 ? 31.739  -27.746 69.785  1.00 51.65  ? 420 LYS E NZ  1 
ATOM   15807 N N   . ASP E 1 421 ? 36.486  -25.857 76.016  1.00 33.59  ? 421 ASP E N   1 
ATOM   15808 C CA  . ASP E 1 421 ? 36.621  -25.655 77.448  1.00 38.79  ? 421 ASP E CA  1 
ATOM   15809 C C   . ASP E 1 421 ? 38.085  -25.832 77.820  1.00 35.07  ? 421 ASP E C   1 
ATOM   15810 O O   . ASP E 1 421 ? 38.690  -26.845 77.472  1.00 33.51  ? 421 ASP E O   1 
ATOM   15811 C CB  . ASP E 1 421 ? 35.736  -26.638 78.224  1.00 37.83  ? 421 ASP E CB  1 
ATOM   15812 C CG  . ASP E 1 421 ? 36.057  -26.657 79.705  1.00 41.22  ? 421 ASP E CG  1 
ATOM   15813 O OD1 . ASP E 1 421 ? 35.688  -25.694 80.416  1.00 44.13  ? 421 ASP E OD1 1 
ATOM   15814 O OD2 . ASP E 1 421 ? 36.708  -27.626 80.153  1.00 43.23  ? 421 ASP E OD2 1 
ATOM   15815 N N   . TRP E 1 422 ? 38.649  -24.851 78.532  1.00 38.27  ? 422 TRP E N   1 
ATOM   15816 C CA  . TRP E 1 422 ? 40.088  -24.849 78.781  1.00 37.83  ? 422 TRP E CA  1 
ATOM   15817 C C   . TRP E 1 422 ? 40.521  -26.036 79.632  1.00 41.89  ? 422 TRP E C   1 
ATOM   15818 O O   . TRP E 1 422 ? 41.618  -26.574 79.444  1.00 41.22  ? 422 TRP E O   1 
ATOM   15819 C CB  . TRP E 1 422 ? 40.500  -23.542 79.450  1.00 44.55  ? 422 TRP E CB  1 
ATOM   15820 C CG  . TRP E 1 422 ? 41.953  -23.476 79.879  1.00 45.88  ? 422 TRP E CG  1 
ATOM   15821 C CD1 . TRP E 1 422 ? 42.419  -23.274 81.148  1.00 48.66  ? 422 TRP E CD1 1 
ATOM   15822 C CD2 . TRP E 1 422 ? 43.110  -23.568 79.037  1.00 44.05  ? 422 TRP E CD2 1 
ATOM   15823 N NE1 . TRP E 1 422 ? 43.795  -23.250 81.151  1.00 53.89  ? 422 TRP E NE1 1 
ATOM   15824 C CE2 . TRP E 1 422 ? 44.244  -23.426 79.868  1.00 51.93  ? 422 TRP E CE2 1 
ATOM   15825 C CE3 . TRP E 1 422 ? 43.300  -23.760 77.664  1.00 47.10  ? 422 TRP E CE3 1 
ATOM   15826 C CZ2 . TRP E 1 422 ? 45.552  -23.479 79.370  1.00 53.08  ? 422 TRP E CZ2 1 
ATOM   15827 C CZ3 . TRP E 1 422 ? 44.610  -23.811 77.168  1.00 47.32  ? 422 TRP E CZ3 1 
ATOM   15828 C CH2 . TRP E 1 422 ? 45.714  -23.675 78.023  1.00 48.63  ? 422 TRP E CH2 1 
ATOM   15829 N N   . ASP E 1 423 ? 39.686  -26.450 80.589  1.00 42.75  ? 423 ASP E N   1 
ATOM   15830 C CA  . ASP E 1 423 ? 40.042  -27.612 81.403  1.00 43.12  ? 423 ASP E CA  1 
ATOM   15831 C C   . ASP E 1 423 ? 39.932  -28.905 80.603  1.00 39.53  ? 423 ASP E C   1 
ATOM   15832 O O   . ASP E 1 423 ? 40.744  -29.821 80.779  1.00 38.77  ? 423 ASP E O   1 
ATOM   15833 C CB  . ASP E 1 423 ? 39.171  -27.679 82.658  1.00 46.16  ? 423 ASP E CB  1 
ATOM   15834 C CG  . ASP E 1 423 ? 39.491  -26.577 83.645  1.00 47.73  ? 423 ASP E CG  1 
ATOM   15835 O OD1 . ASP E 1 423 ? 40.572  -25.964 83.516  1.00 47.82  ? 423 ASP E OD1 1 
ATOM   15836 O OD2 . ASP E 1 423 ? 38.666  -26.329 84.553  1.00 53.07  ? 423 ASP E OD2 1 
ATOM   15837 N N   . ARG E 1 424 ? 38.938  -29.002 79.719  1.00 36.54  ? 424 ARG E N   1 
ATOM   15838 C CA  . ARG E 1 424 ? 38.864  -30.169 78.849  1.00 40.91  ? 424 ARG E CA  1 
ATOM   15839 C C   . ARG E 1 424 ? 40.077  -30.243 77.925  1.00 40.45  ? 424 ARG E C   1 
ATOM   15840 O O   . ARG E 1 424 ? 40.535  -31.338 77.587  1.00 43.64  ? 424 ARG E O   1 
ATOM   15841 C CB  . ARG E 1 424 ? 37.560  -30.144 78.061  1.00 38.62  ? 424 ARG E CB  1 
ATOM   15842 C CG  . ARG E 1 424 ? 37.344  -31.366 77.196  1.00 50.12  ? 424 ARG E CG  1 
ATOM   15843 C CD  . ARG E 1 424 ? 35.848  -31.629 76.920  1.00 48.86  ? 424 ARG E CD  1 
ATOM   15844 N NE  . ARG E 1 424 ? 35.225  -30.617 76.074  1.00 45.79  ? 424 ARG E NE  1 
ATOM   15845 C CZ  . ARG E 1 424 ? 34.437  -29.645 76.519  1.00 50.35  ? 424 ARG E CZ  1 
ATOM   15846 N NH1 . ARG E 1 424 ? 34.139  -29.531 77.805  1.00 48.40  ? 424 ARG E NH1 1 
ATOM   15847 N NH2 . ARG E 1 424 ? 33.932  -28.770 75.651  1.00 45.81  ? 424 ARG E NH2 1 
ATOM   15848 N N   . LEU E 1 425 ? 40.645  -29.096 77.554  1.00 38.36  ? 425 LEU E N   1 
ATOM   15849 C CA  . LEU E 1 425 ? 41.860  -29.112 76.745  1.00 38.34  ? 425 LEU E CA  1 
ATOM   15850 C C   . LEU E 1 425 ? 43.032  -29.675 77.533  1.00 38.10  ? 425 LEU E C   1 
ATOM   15851 O O   . LEU E 1 425 ? 43.811  -30.483 77.010  1.00 39.43  ? 425 LEU E O   1 
ATOM   15852 C CB  . LEU E 1 425 ? 42.184  -27.697 76.261  1.00 39.82  ? 425 LEU E CB  1 
ATOM   15853 C CG  . LEU E 1 425 ? 42.960  -27.477 74.953  1.00 35.32  ? 425 LEU E CG  1 
ATOM   15854 C CD1 . LEU E 1 425 ? 43.206  -25.997 74.767  1.00 34.94  ? 425 LEU E CD1 1 
ATOM   15855 C CD2 . LEU E 1 425 ? 44.273  -28.247 74.874  1.00 36.59  ? 425 LEU E CD2 1 
ATOM   15856 N N   . THR E 1 426 ? 43.181  -29.245 78.785  1.00 33.00  ? 426 THR E N   1 
ATOM   15857 C CA  . THR E 1 426 ? 44.274  -29.730 79.619  1.00 40.31  ? 426 THR E CA  1 
ATOM   15858 C C   . THR E 1 426 ? 44.255  -31.251 79.738  1.00 36.77  ? 426 THR E C   1 
ATOM   15859 O O   . THR E 1 426 ? 45.298  -31.903 79.620  1.00 36.00  ? 426 THR E O   1 
ATOM   15860 C CB  . THR E 1 426 ? 44.185  -29.068 80.993  1.00 40.09  ? 426 THR E CB  1 
ATOM   15861 O OG1 . THR E 1 426 ? 44.564  -27.689 80.875  1.00 43.52  ? 426 THR E OG1 1 
ATOM   15862 C CG2 . THR E 1 426 ? 45.077  -29.773 82.001  1.00 39.13  ? 426 THR E CG2 1 
ATOM   15863 N N   . ALA E 1 427 ? 43.074  -31.832 79.960  1.00 37.34  ? 427 ALA E N   1 
ATOM   15864 C CA  . ALA E 1 427 ? 42.975  -33.282 80.053  1.00 38.15  ? 427 ALA E CA  1 
ATOM   15865 C C   . ALA E 1 427 ? 43.356  -33.939 78.740  1.00 35.77  ? 427 ALA E C   1 
ATOM   15866 O O   . ALA E 1 427 ? 44.006  -34.988 78.732  1.00 40.27  ? 427 ALA E O   1 
ATOM   15867 C CB  . ALA E 1 427 ? 41.561  -33.697 80.466  1.00 39.88  ? 427 ALA E CB  1 
ATOM   15868 N N   . MET E 1 428 ? 42.951  -33.347 77.615  1.00 34.60  ? 428 MET E N   1 
ATOM   15869 C CA  . MET E 1 428 ? 43.323  -33.924 76.332  1.00 36.56  ? 428 MET E CA  1 
ATOM   15870 C C   . MET E 1 428 ? 44.837  -34.010 76.206  1.00 35.79  ? 428 MET E C   1 
ATOM   15871 O O   . MET E 1 428 ? 45.367  -35.019 75.734  1.00 32.34  ? 428 MET E O   1 
ATOM   15872 C CB  . MET E 1 428 ? 42.737  -33.112 75.176  1.00 34.60  ? 428 MET E CB  1 
ATOM   15873 C CG  . MET E 1 428 ? 41.218  -33.191 75.034  1.00 40.48  ? 428 MET E CG  1 
ATOM   15874 S SD  . MET E 1 428 ? 40.663  -32.315 73.544  1.00 39.72  ? 428 MET E SD  1 
ATOM   15875 C CE  . MET E 1 428 ? 38.930  -32.782 73.501  1.00 47.78  ? 428 MET E CE  1 
ATOM   15876 N N   . LYS E 1 429 ? 45.547  -32.965 76.648  1.00 36.06  ? 429 LYS E N   1 
ATOM   15877 C CA  . LYS E 1 429 ? 47.004  -32.959 76.581  1.00 38.13  ? 429 LYS E CA  1 
ATOM   15878 C C   . LYS E 1 429 ? 47.600  -34.068 77.439  1.00 36.22  ? 429 LYS E C   1 
ATOM   15879 O O   . LYS E 1 429 ? 48.488  -34.795 76.981  1.00 34.76  ? 429 LYS E O   1 
ATOM   15880 C CB  . LYS E 1 429 ? 47.543  -31.587 76.996  1.00 37.08  ? 429 LYS E CB  1 
ATOM   15881 C CG  . LYS E 1 429 ? 47.293  -30.501 75.936  1.00 39.07  ? 429 LYS E CG  1 
ATOM   15882 C CD  . LYS E 1 429 ? 47.506  -29.097 76.472  1.00 41.12  ? 429 LYS E CD  1 
ATOM   15883 C CE  . LYS E 1 429 ? 48.960  -28.694 76.364  1.00 38.44  ? 429 LYS E CE  1 
ATOM   15884 N NZ  . LYS E 1 429 ? 49.388  -27.849 77.517  1.00 39.50  ? 429 LYS E NZ  1 
ATOM   15885 N N   . ASP E 1 430 ? 47.091  -34.239 78.665  1.00 37.42  ? 430 ASP E N   1 
ATOM   15886 C CA  . ASP E 1 430 ? 47.544  -35.332 79.533  1.00 43.46  ? 430 ASP E CA  1 
ATOM   15887 C C   . ASP E 1 430 ? 47.289  -36.692 78.896  1.00 42.30  ? 430 ASP E C   1 
ATOM   15888 O O   . ASP E 1 430 ? 48.165  -37.566 78.905  1.00 39.78  ? 430 ASP E O   1 
ATOM   15889 C CB  . ASP E 1 430 ? 46.853  -35.261 80.899  1.00 39.29  ? 430 ASP E CB  1 
ATOM   15890 C CG  . ASP E 1 430 ? 47.523  -34.281 81.837  1.00 53.14  ? 430 ASP E CG  1 
ATOM   15891 O OD1 . ASP E 1 430 ? 47.897  -33.176 81.374  1.00 49.36  ? 430 ASP E OD1 1 
ATOM   15892 O OD2 . ASP E 1 430 ? 47.702  -34.623 83.030  1.00 63.65  ? 430 ASP E OD2 1 
ATOM   15893 N N   . GLU E 1 431 ? 46.086  -36.893 78.352  1.00 38.55  ? 431 GLU E N   1 
ATOM   15894 C CA  . GLU E 1 431 ? 45.794  -38.147 77.672  1.00 38.95  ? 431 GLU E CA  1 
ATOM   15895 C C   . GLU E 1 431 ? 46.764  -38.376 76.526  1.00 39.43  ? 431 GLU E C   1 
ATOM   15896 O O   . GLU E 1 431 ? 47.256  -39.493 76.335  1.00 38.63  ? 431 GLU E O   1 
ATOM   15897 C CB  . GLU E 1 431 ? 44.351  -38.150 77.165  1.00 42.53  ? 431 GLU E CB  1 
ATOM   15898 C CG  . GLU E 1 431 ? 43.282  -38.256 78.267  1.00 52.27  ? 431 GLU E CG  1 
ATOM   15899 C CD  . GLU E 1 431 ? 43.349  -39.585 79.036  1.00 60.67  ? 431 GLU E CD  1 
ATOM   15900 O OE1 . GLU E 1 431 ? 43.674  -39.570 80.252  1.00 59.09  ? 431 GLU E OE1 1 
ATOM   15901 O OE2 . GLU E 1 431 ? 43.096  -40.647 78.418  1.00 59.21  ? 431 GLU E OE2 1 
ATOM   15902 N N   . ILE E 1 432 ? 47.074  -37.318 75.769  1.00 37.22  ? 432 ILE E N   1 
ATOM   15903 C CA  . ILE E 1 432 ? 48.015  -37.441 74.662  1.00 34.91  ? 432 ILE E CA  1 
ATOM   15904 C C   . ILE E 1 432 ? 49.391  -37.833 75.179  1.00 33.46  ? 432 ILE E C   1 
ATOM   15905 O O   . ILE E 1 432 ? 50.040  -38.729 74.636  1.00 37.06  ? 432 ILE E O   1 
ATOM   15906 C CB  . ILE E 1 432 ? 48.076  -36.134 73.854  1.00 32.32  ? 432 ILE E CB  1 
ATOM   15907 C CG1 . ILE E 1 432 ? 46.796  -35.951 73.058  1.00 33.52  ? 432 ILE E CG1 1 
ATOM   15908 C CG2 . ILE E 1 432 ? 49.269  -36.156 72.913  1.00 28.80  ? 432 ILE E CG2 1 
ATOM   15909 C CD1 . ILE E 1 432 ? 46.775  -34.712 72.200  1.00 33.01  ? 432 ILE E CD1 1 
ATOM   15910 N N   . ALA E 1 433 ? 49.855  -37.165 76.237  1.00 35.86  ? 433 ALA E N   1 
ATOM   15911 C CA  . ALA E 1 433 ? 51.173  -37.475 76.791  1.00 40.43  ? 433 ALA E CA  1 
ATOM   15912 C C   . ALA E 1 433 ? 51.243  -38.914 77.279  1.00 39.72  ? 433 ALA E C   1 
ATOM   15913 O O   . ALA E 1 433 ? 52.215  -39.624 77.007  1.00 39.21  ? 433 ALA E O   1 
ATOM   15914 C CB  . ALA E 1 433 ? 51.505  -36.517 77.932  1.00 39.35  ? 433 ALA E CB  1 
ATOM   15915 N N   . THR E 1 434 ? 50.217  -39.363 77.997  1.00 38.23  ? 434 THR E N   1 
ATOM   15916 C CA  . THR E 1 434 ? 50.165  -40.755 78.424  1.00 43.38  ? 434 THR E CA  1 
ATOM   15917 C C   . THR E 1 434 ? 50.240  -41.703 77.232  1.00 45.20  ? 434 THR E C   1 
ATOM   15918 O O   . THR E 1 434 ? 51.041  -42.646 77.219  1.00 46.82  ? 434 THR E O   1 
ATOM   15919 C CB  . THR E 1 434 ? 48.888  -40.983 79.227  1.00 43.32  ? 434 THR E CB  1 
ATOM   15920 O OG1 . THR E 1 434 ? 49.107  -40.557 80.579  1.00 49.98  ? 434 THR E OG1 1 
ATOM   15921 C CG2 . THR E 1 434 ? 48.481  -42.450 79.197  1.00 46.08  ? 434 THR E CG2 1 
ATOM   15922 N N   . THR E 1 435 ? 49.426  -41.450 76.209  1.00 45.30  ? 435 THR E N   1 
ATOM   15923 C CA  . THR E 1 435 ? 49.317  -42.364 75.078  1.00 41.10  ? 435 THR E CA  1 
ATOM   15924 C C   . THR E 1 435 ? 50.533  -42.265 74.163  1.00 38.38  ? 435 THR E C   1 
ATOM   15925 O O   . THR E 1 435 ? 51.185  -43.271 73.869  1.00 41.88  ? 435 THR E O   1 
ATOM   15926 C CB  . THR E 1 435 ? 48.031  -42.065 74.296  1.00 39.57  ? 435 THR E CB  1 
ATOM   15927 O OG1 . THR E 1 435 ? 46.989  -41.713 75.211  1.00 48.20  ? 435 THR E OG1 1 
ATOM   15928 C CG2 . THR E 1 435 ? 47.591  -43.274 73.545  1.00 34.22  ? 435 THR E CG2 1 
ATOM   15929 N N   . ALA E 1 436 ? 50.840  -41.061 73.674  1.00 37.61  ? 436 ALA E N   1 
ATOM   15930 C CA  . ALA E 1 436 ? 51.905  -40.933 72.690  1.00 32.36  ? 436 ALA E CA  1 
ATOM   15931 C C   . ALA E 1 436 ? 53.267  -40.811 73.342  1.00 36.89  ? 436 ALA E C   1 
ATOM   15932 O O   . ALA E 1 436 ? 54.273  -41.179 72.723  1.00 35.46  ? 436 ALA E O   1 
ATOM   15933 C CB  . ALA E 1 436 ? 51.658  -39.736 71.770  1.00 33.81  ? 436 ALA E CB  1 
ATOM   15934 N N   . GLY E 1 437 ? 53.325  -40.344 74.585  1.00 38.82  ? 437 GLY E N   1 
ATOM   15935 C CA  . GLY E 1 437 ? 54.609  -40.206 75.245  1.00 39.99  ? 437 GLY E CA  1 
ATOM   15936 C C   . GLY E 1 437 ? 55.259  -38.867 74.985  1.00 41.77  ? 437 GLY E C   1 
ATOM   15937 O O   . GLY E 1 437 ? 55.163  -38.329 73.879  1.00 43.83  ? 437 GLY E O   1 
ATOM   15938 N N   . THR E 1 438 ? 55.916  -38.317 76.000  1.00 43.23  ? 438 THR E N   1 
ATOM   15939 C CA  . THR E 1 438 ? 56.591  -37.035 75.901  1.00 47.18  ? 438 THR E CA  1 
ATOM   15940 C C   . THR E 1 438 ? 58.083  -37.225 76.110  1.00 50.10  ? 438 THR E C   1 
ATOM   15941 O O   . THR E 1 438 ? 58.501  -37.957 77.014  1.00 54.17  ? 438 THR E O   1 
ATOM   15942 C CB  . THR E 1 438 ? 56.053  -36.040 76.936  1.00 46.54  ? 438 THR E CB  1 
ATOM   15943 O OG1 . THR E 1 438 ? 55.803  -36.722 78.173  1.00 57.03  ? 438 THR E OG1 1 
ATOM   15944 C CG2 . THR E 1 438 ? 54.759  -35.431 76.436  1.00 46.32  ? 438 THR E CG2 1 
ATOM   15945 N N   . LEU E 1 439 ? 58.877  -36.574 75.260  1.00 47.34  ? 439 LEU E N   1 
ATOM   15946 C CA  . LEU E 1 439 ? 60.317  -36.455 75.470  1.00 54.05  ? 439 LEU E CA  1 
ATOM   15947 C C   . LEU E 1 439 ? 60.577  -35.469 76.605  1.00 60.17  ? 439 LEU E C   1 
ATOM   15948 O O   . LEU E 1 439 ? 60.302  -34.272 76.472  1.00 64.04  ? 439 LEU E O   1 
ATOM   15949 C CB  . LEU E 1 439 ? 61.007  -36.000 74.188  1.00 48.82  ? 439 LEU E CB  1 
ATOM   15950 C CG  . LEU E 1 439 ? 61.101  -37.055 73.081  1.00 49.48  ? 439 LEU E CG  1 
ATOM   15951 C CD1 . LEU E 1 439 ? 62.061  -36.634 71.985  1.00 37.24  ? 439 LEU E CD1 1 
ATOM   15952 C CD2 . LEU E 1 439 ? 61.510  -38.391 73.679  1.00 47.21  ? 439 LEU E CD2 1 
ATOM   15953 N N   . SER E 1 440 ? 61.101  -35.964 77.721  1.00 60.55  ? 440 SER E N   1 
ATOM   15954 C CA  . SER E 1 440 ? 61.320  -35.117 78.891  1.00 66.89  ? 440 SER E CA  1 
ATOM   15955 C C   . SER E 1 440 ? 62.690  -34.441 78.837  1.00 72.94  ? 440 SER E C   1 
ATOM   15956 O O   . SER E 1 440 ? 63.207  -34.135 77.758  1.00 73.88  ? 440 SER E O   1 
ATOM   15957 C CB  . SER E 1 440 ? 61.186  -35.930 80.183  1.00 66.79  ? 440 SER E CB  1 
ATOM   15958 O OG  . SER E 1 440 ? 62.215  -36.902 80.285  1.00 59.48  ? 440 SER E OG  1 
ATOM   15959 N N   . MET F 1 1   ? -21.245 32.984  78.944  1.00 57.36  ? 1   MET F N   1 
ATOM   15960 C CA  . MET F 1 1   ? -20.969 31.556  78.876  1.00 58.04  ? 1   MET F CA  1 
ATOM   15961 C C   . MET F 1 1   ? -19.590 31.275  78.282  1.00 59.65  ? 1   MET F C   1 
ATOM   15962 O O   . MET F 1 1   ? -19.470 31.045  77.070  1.00 61.92  ? 1   MET F O   1 
ATOM   15963 C CB  . MET F 1 1   ? -22.034 30.826  78.044  1.00 55.95  ? 1   MET F CB  1 
ATOM   15964 C CG  . MET F 1 1   ? -23.262 30.363  78.804  1.00 60.91  ? 1   MET F CG  1 
ATOM   15965 S SD  . MET F 1 1   ? -23.772 28.694  78.309  1.00 78.58  ? 1   MET F SD  1 
ATOM   15966 C CE  . MET F 1 1   ? -22.543 27.648  79.099  1.00 47.33  ? 1   MET F CE  1 
ATOM   15967 N N   . PRO F 1 2   ? -18.548 31.276  79.114  1.00 49.59  ? 2   PRO F N   1 
ATOM   15968 C CA  . PRO F 1 2   ? -17.227 30.914  78.601  1.00 45.12  ? 2   PRO F CA  1 
ATOM   15969 C C   . PRO F 1 2   ? -17.221 29.461  78.156  1.00 39.35  ? 2   PRO F C   1 
ATOM   15970 O O   . PRO F 1 2   ? -17.973 28.623  78.658  1.00 35.85  ? 2   PRO F O   1 
ATOM   15971 C CB  . PRO F 1 2   ? -16.289 31.152  79.795  1.00 42.67  ? 2   PRO F CB  1 
ATOM   15972 C CG  . PRO F 1 2   ? -17.068 31.970  80.763  1.00 45.45  ? 2   PRO F CG  1 
ATOM   15973 C CD  . PRO F 1 2   ? -18.508 31.629  80.541  1.00 45.11  ? 2   PRO F CD  1 
ATOM   15974 N N   . LYS F 1 3   ? -16.387 29.176  77.175  1.00 35.18  ? 3   LYS F N   1 
ATOM   15975 C CA  . LYS F 1 3   ? -16.227 27.821  76.677  1.00 34.57  ? 3   LYS F CA  1 
ATOM   15976 C C   . LYS F 1 3   ? -14.740 27.533  76.573  1.00 30.58  ? 3   LYS F C   1 
ATOM   15977 O O   . LYS F 1 3   ? -13.944 28.438  76.325  1.00 27.74  ? 3   LYS F O   1 
ATOM   15978 C CB  . LYS F 1 3   ? -16.920 27.628  75.302  1.00 27.85  ? 3   LYS F CB  1 
ATOM   15979 C CG  . LYS F 1 3   ? -16.395 28.560  74.184  1.00 32.75  ? 3   LYS F CG  1 
ATOM   15980 C CD  . LYS F 1 3   ? -17.082 28.352  72.808  1.00 28.64  ? 3   LYS F CD  1 
ATOM   15981 C CE  . LYS F 1 3   ? -16.622 29.393  71.762  1.00 27.51  ? 3   LYS F CE  1 
ATOM   15982 N NZ  . LYS F 1 3   ? -16.904 30.807  72.162  1.00 23.18  ? 3   LYS F NZ  1 
ATOM   15983 N N   . ILE F 1 4   ? -14.369 26.271  76.763  1.00 30.50  ? 4   ILE F N   1 
ATOM   15984 C CA  . ILE F 1 4   ? -13.002 25.819  76.530  1.00 26.21  ? 4   ILE F CA  1 
ATOM   15985 C C   . ILE F 1 4   ? -12.908 25.350  75.081  1.00 28.24  ? 4   ILE F C   1 
ATOM   15986 O O   . ILE F 1 4   ? -13.507 24.339  74.717  1.00 29.69  ? 4   ILE F O   1 
ATOM   15987 C CB  . ILE F 1 4   ? -12.622 24.688  77.496  1.00 32.90  ? 4   ILE F CB  1 
ATOM   15988 C CG1 . ILE F 1 4   ? -12.583 25.183  78.942  1.00 31.22  ? 4   ILE F CG1 1 
ATOM   15989 C CG2 . ILE F 1 4   ? -11.295 24.065  77.103  1.00 28.38  ? 4   ILE F CG2 1 
ATOM   15990 C CD1 . ILE F 1 4   ? -12.394 24.070  79.933  1.00 31.33  ? 4   ILE F CD1 1 
ATOM   15991 N N   . ILE F 1 5   ? -12.139 26.056  74.254  1.00 28.01  ? 5   ILE F N   1 
ATOM   15992 C CA  . ILE F 1 5   ? -11.996 25.694  72.842  1.00 27.62  ? 5   ILE F CA  1 
ATOM   15993 C C   . ILE F 1 5   ? -10.923 24.618  72.710  1.00 33.22  ? 5   ILE F C   1 
ATOM   15994 O O   . ILE F 1 5   ? -9.739  24.894  72.927  1.00 34.49  ? 5   ILE F O   1 
ATOM   15995 C CB  . ILE F 1 5   ? -11.645 26.907  71.977  1.00 29.51  ? 5   ILE F CB  1 
ATOM   15996 C CG1 . ILE F 1 5   ? -12.737 27.966  72.048  1.00 25.99  ? 5   ILE F CG1 1 
ATOM   15997 C CG2 . ILE F 1 5   ? -11.397 26.463  70.536  1.00 26.20  ? 5   ILE F CG2 1 
ATOM   15998 C CD1 . ILE F 1 5   ? -12.188 29.337  72.051  1.00 26.28  ? 5   ILE F CD1 1 
ATOM   15999 N N   . LEU F 1 6   ? -11.318 23.406  72.305  1.00 30.96  ? 6   LEU F N   1 
ATOM   16000 C CA  . LEU F 1 6   ? -10.450 22.229  72.430  1.00 26.97  ? 6   LEU F CA  1 
ATOM   16001 C C   . LEU F 1 6   ? -10.200 21.604  71.060  1.00 33.42  ? 6   LEU F C   1 
ATOM   16002 O O   . LEU F 1 6   ? -11.047 20.843  70.556  1.00 28.92  ? 6   LEU F O   1 
ATOM   16003 C CB  . LEU F 1 6   ? -11.083 21.221  73.388  1.00 30.63  ? 6   LEU F CB  1 
ATOM   16004 C CG  . LEU F 1 6   ? -10.356 19.997  73.979  1.00 36.41  ? 6   LEU F CG  1 
ATOM   16005 C CD1 . LEU F 1 6   ? -11.325 19.188  74.836  1.00 39.89  ? 6   LEU F CD1 1 
ATOM   16006 C CD2 . LEU F 1 6   ? -9.718  19.075  72.981  1.00 35.93  ? 6   LEU F CD2 1 
ATOM   16007 N N   . PRO F 1 7   ? -9.074  21.920  70.401  1.00 34.40  ? 7   PRO F N   1 
ATOM   16008 C CA  . PRO F 1 7   ? -8.791  21.338  69.077  1.00 31.94  ? 7   PRO F CA  1 
ATOM   16009 C C   . PRO F 1 7   ? -8.067  20.004  69.121  1.00 34.12  ? 7   PRO F C   1 
ATOM   16010 O O   . PRO F 1 7   ? -6.841  19.966  69.015  1.00 32.90  ? 7   PRO F O   1 
ATOM   16011 C CB  . PRO F 1 7   ? -7.903  22.396  68.409  1.00 33.42  ? 7   PRO F CB  1 
ATOM   16012 C CG  . PRO F 1 7   ? -7.280  23.133  69.539  1.00 38.31  ? 7   PRO F CG  1 
ATOM   16013 C CD  . PRO F 1 7   ? -8.288  23.139  70.651  1.00 33.00  ? 7   PRO F CD  1 
ATOM   16014 N N   . ASN F 1 8   ? -8.804  18.904  69.223  1.00 34.58  ? 8   ASN F N   1 
ATOM   16015 C CA  . ASN F 1 8   ? -8.185  17.588  69.338  1.00 35.27  ? 8   ASN F CA  1 
ATOM   16016 C C   . ASN F 1 8   ? -8.198  16.869  67.987  1.00 37.65  ? 8   ASN F C   1 
ATOM   16017 O O   . ASN F 1 8   ? -8.871  15.863  67.788  1.00 39.48  ? 8   ASN F O   1 
ATOM   16018 C CB  . ASN F 1 8   ? -8.879  16.772  70.428  1.00 35.96  ? 8   ASN F CB  1 
ATOM   16019 C CG  . ASN F 1 8   ? -10.387 16.949  70.429  1.00 32.26  ? 8   ASN F CG  1 
ATOM   16020 O OD1 . ASN F 1 8   ? -10.923 17.864  69.807  1.00 33.50  ? 8   ASN F OD1 1 
ATOM   16021 N ND2 . ASN F 1 8   ? -11.079 16.071  71.135  1.00 31.85  ? 8   ASN F ND2 1 
ATOM   16022 N N   . PHE F 1 9   ? -7.419  17.407  67.048  1.00 43.40  ? 9   PHE F N   1 
ATOM   16023 C CA  . PHE F 1 9   ? -7.127  16.706  65.795  1.00 50.13  ? 9   PHE F CA  1 
ATOM   16024 C C   . PHE F 1 9   ? -6.696  15.255  66.038  1.00 44.61  ? 9   PHE F C   1 
ATOM   16025 O O   . PHE F 1 9   ? -6.054  14.630  65.191  1.00 48.84  ? 9   PHE F O   1 
ATOM   16026 C CB  . PHE F 1 9   ? -6.031  17.433  65.013  1.00 54.18  ? 9   PHE F CB  1 
ATOM   16027 C CG  . PHE F 1 9   ? -6.552  18.419  64.013  1.00 58.65  ? 9   PHE F CG  1 
ATOM   16028 C CD1 . PHE F 1 9   ? -5.959  18.528  62.757  1.00 62.14  ? 9   PHE F CD1 1 
ATOM   16029 C CD2 . PHE F 1 9   ? -7.626  19.242  64.324  1.00 52.85  ? 9   PHE F CD2 1 
ATOM   16030 C CE1 . PHE F 1 9   ? -6.433  19.436  61.825  1.00 64.56  ? 9   PHE F CE1 1 
ATOM   16031 C CE2 . PHE F 1 9   ? -8.109  20.156  63.400  1.00 60.30  ? 9   PHE F CE2 1 
ATOM   16032 C CZ  . PHE F 1 9   ? -7.515  20.256  62.148  1.00 65.71  ? 9   PHE F CZ  1 
ATOM   16033 N N   . THR F 1 31  ? 5.551   25.929  64.923  1.00 31.37  ? 31  THR F N   1 
ATOM   16034 C CA  . THR F 1 31  ? 4.392   26.208  64.087  1.00 41.17  ? 31  THR F CA  1 
ATOM   16035 C C   . THR F 1 31  ? 3.191   26.678  64.923  1.00 41.89  ? 31  THR F C   1 
ATOM   16036 O O   . THR F 1 31  ? 3.147   26.471  66.134  1.00 41.32  ? 31  THR F O   1 
ATOM   16037 C CB  . THR F 1 31  ? 3.984   24.961  63.259  1.00 44.97  ? 31  THR F CB  1 
ATOM   16038 O OG1 . THR F 1 31  ? 4.160   23.785  64.052  1.00 49.65  ? 31  THR F OG1 1 
ATOM   16039 C CG2 . THR F 1 31  ? 4.833   24.842  61.988  1.00 39.20  ? 31  THR F CG2 1 
ATOM   16040 N N   . ASP F 1 32  ? 2.215   27.310  64.279  1.00 37.26  ? 32  ASP F N   1 
ATOM   16041 C CA  . ASP F 1 32  ? 1.064   27.873  64.978  1.00 38.66  ? 32  ASP F CA  1 
ATOM   16042 C C   . ASP F 1 32  ? -0.223  27.467  64.281  1.00 38.61  ? 32  ASP F C   1 
ATOM   16043 O O   . ASP F 1 32  ? -1.096  28.286  63.987  1.00 30.38  ? 32  ASP F O   1 
ATOM   16044 C CB  . ASP F 1 32  ? 1.176   29.395  65.101  1.00 37.14  ? 32  ASP F CB  1 
ATOM   16045 C CG  . ASP F 1 32  ? 1.080   30.115  63.758  1.00 38.71  ? 32  ASP F CG  1 
ATOM   16046 O OD1 . ASP F 1 32  ? 1.184   29.439  62.708  1.00 39.44  ? 32  ASP F OD1 1 
ATOM   16047 O OD2 . ASP F 1 32  ? 0.881   31.359  63.752  1.00 29.33  ? 32  ASP F OD2 1 
ATOM   16048 N N   . THR F 1 33  ? -0.340  26.165  64.006  1.00 39.09  ? 33  THR F N   1 
ATOM   16049 C CA  . THR F 1 33  ? -1.492  25.645  63.278  1.00 37.30  ? 33  THR F CA  1 
ATOM   16050 C C   . THR F 1 33  ? -2.797  25.910  64.019  1.00 33.32  ? 33  THR F C   1 
ATOM   16051 O O   . THR F 1 33  ? -3.818  26.223  63.396  1.00 32.15  ? 33  THR F O   1 
ATOM   16052 C CB  . THR F 1 33  ? -1.333  24.141  63.056  1.00 45.39  ? 33  THR F CB  1 
ATOM   16053 O OG1 . THR F 1 33  ? 0.050   23.834  62.852  1.00 46.33  ? 33  THR F OG1 1 
ATOM   16054 C CG2 . THR F 1 33  ? -2.128  23.703  61.848  1.00 43.96  ? 33  THR F CG2 1 
ATOM   16055 N N   . THR F 1 34  ? -2.800  25.756  65.341  1.00 28.52  ? 34  THR F N   1 
ATOM   16056 C CA  . THR F 1 34  ? -4.066  25.816  66.059  1.00 30.94  ? 34  THR F CA  1 
ATOM   16057 C C   . THR F 1 34  ? -4.458  27.237  66.421  1.00 29.36  ? 34  THR F C   1 
ATOM   16058 O O   . THR F 1 34  ? -5.572  27.452  66.912  1.00 30.34  ? 34  THR F O   1 
ATOM   16059 C CB  . THR F 1 34  ? -4.020  24.939  67.329  1.00 33.28  ? 34  THR F CB  1 
ATOM   16060 O OG1 . THR F 1 34  ? -3.510  25.699  68.429  1.00 40.58  ? 34  THR F OG1 1 
ATOM   16061 C CG2 . THR F 1 34  ? -3.134  23.761  67.128  1.00 33.65  ? 34  THR F CG2 1 
ATOM   16062 N N   . ALA F 1 35  ? -3.577  28.210  66.182  1.00 29.42  ? 35  ALA F N   1 
ATOM   16063 C CA  . ALA F 1 35  ? -3.895  29.588  66.542  1.00 30.15  ? 35  ALA F CA  1 
ATOM   16064 C C   . ALA F 1 35  ? -5.139  30.068  65.815  1.00 29.72  ? 35  ALA F C   1 
ATOM   16065 O O   . ALA F 1 35  ? -5.837  30.963  66.304  1.00 28.30  ? 35  ALA F O   1 
ATOM   16066 C CB  . ALA F 1 35  ? -2.716  30.509  66.222  1.00 26.09  ? 35  ALA F CB  1 
ATOM   16067 N N   . ARG F 1 36  ? -5.425  29.481  64.649  1.00 25.56  ? 36  ARG F N   1 
ATOM   16068 C CA  . ARG F 1 36  ? -6.614  29.848  63.900  1.00 27.39  ? 36  ARG F CA  1 
ATOM   16069 C C   . ARG F 1 36  ? -7.871  29.684  64.743  1.00 24.30  ? 36  ARG F C   1 
ATOM   16070 O O   . ARG F 1 36  ? -8.840  30.420  64.561  1.00 27.28  ? 36  ARG F O   1 
ATOM   16071 C CB  . ARG F 1 36  ? -6.698  29.006  62.624  1.00 26.42  ? 36  ARG F CB  1 
ATOM   16072 C CG  . ARG F 1 36  ? -7.145  27.561  62.889  1.00 29.09  ? 36  ARG F CG  1 
ATOM   16073 C CD  . ARG F 1 36  ? -6.652  26.588  61.829  1.00 28.24  ? 36  ARG F CD  1 
ATOM   16074 N NE  . ARG F 1 36  ? -7.091  26.933  60.478  1.00 27.47  ? 36  ARG F NE  1 
ATOM   16075 C CZ  . ARG F 1 36  ? -8.189  26.456  59.909  1.00 29.26  ? 36  ARG F CZ  1 
ATOM   16076 N NH1 . ARG F 1 36  ? -9.036  25.688  60.579  1.00 24.54  ? 36  ARG F NH1 1 
ATOM   16077 N NH2 . ARG F 1 36  ? -8.445  26.754  58.636  1.00 27.77  ? 36  ARG F NH2 1 
ATOM   16078 N N   . PHE F 1 37  ? -7.866  28.759  65.697  1.00 28.43  ? 37  PHE F N   1 
ATOM   16079 C CA  . PHE F 1 37  ? -9.079  28.556  66.467  1.00 28.28  ? 37  PHE F CA  1 
ATOM   16080 C C   . PHE F 1 37  ? -9.347  29.692  67.448  1.00 28.94  ? 37  PHE F C   1 
ATOM   16081 O O   . PHE F 1 37  ? -10.475 29.801  67.945  1.00 24.22  ? 37  PHE F O   1 
ATOM   16082 C CB  . PHE F 1 37  ? -9.013  27.182  67.138  1.00 29.22  ? 37  PHE F CB  1 
ATOM   16083 C CG  . PHE F 1 37  ? -8.950  26.051  66.131  1.00 30.38  ? 37  PHE F CG  1 
ATOM   16084 C CD1 . PHE F 1 37  ? -9.965  25.881  65.203  1.00 34.44  ? 37  PHE F CD1 1 
ATOM   16085 C CD2 . PHE F 1 37  ? -7.860  25.207  66.068  1.00 34.32  ? 37  PHE F CD2 1 
ATOM   16086 C CE1 . PHE F 1 37  ? -9.907  24.864  64.254  1.00 35.79  ? 37  PHE F CE1 1 
ATOM   16087 C CE2 . PHE F 1 37  ? -7.798  24.195  65.125  1.00 35.65  ? 37  PHE F CE2 1 
ATOM   16088 C CZ  . PHE F 1 37  ? -8.830  24.025  64.214  1.00 30.81  ? 37  PHE F CZ  1 
ATOM   16089 N N   . LEU F 1 38  ? -8.377  30.591  67.658  1.00 28.18  ? 38  LEU F N   1 
ATOM   16090 C CA  . LEU F 1 38  ? -8.613  31.791  68.468  1.00 28.67  ? 38  LEU F CA  1 
ATOM   16091 C C   . LEU F 1 38  ? -9.818  32.591  67.981  1.00 26.46  ? 38  LEU F C   1 
ATOM   16092 O O   . LEU F 1 38  ? -10.512 33.227  68.784  1.00 26.36  ? 38  LEU F O   1 
ATOM   16093 C CB  . LEU F 1 38  ? -7.368  32.678  68.453  1.00 32.57  ? 38  LEU F CB  1 
ATOM   16094 C CG  . LEU F 1 38  ? -6.485  32.726  69.701  1.00 35.64  ? 38  LEU F CG  1 
ATOM   16095 C CD1 . LEU F 1 38  ? -5.316  33.659  69.431  1.00 37.92  ? 38  LEU F CD1 1 
ATOM   16096 C CD2 . LEU F 1 38  ? -7.283  33.155  70.943  1.00 28.24  ? 38  LEU F CD2 1 
ATOM   16097 N N   . TRP F 1 39  ? -10.089 32.572  66.677  1.00 25.48  ? 39  TRP F N   1 
ATOM   16098 C CA  . TRP F 1 39  ? -11.221 33.318  66.148  1.00 24.17  ? 39  TRP F CA  1 
ATOM   16099 C C   . TRP F 1 39  ? -12.572 32.765  66.598  1.00 29.26  ? 39  TRP F C   1 
ATOM   16100 O O   . TRP F 1 39  ? -13.608 33.350  66.222  1.00 24.04  ? 39  TRP F O   1 
ATOM   16101 C CB  . TRP F 1 39  ? -11.146 33.358  64.622  1.00 28.44  ? 39  TRP F CB  1 
ATOM   16102 C CG  . TRP F 1 39  ? -9.974  34.145  64.106  1.00 25.32  ? 39  TRP F CG  1 
ATOM   16103 C CD1 . TRP F 1 39  ? -8.701  33.679  63.904  1.00 26.68  ? 39  TRP F CD1 1 
ATOM   16104 C CD2 . TRP F 1 39  ? -9.956  35.530  63.738  1.00 26.02  ? 39  TRP F CD2 1 
ATOM   16105 N NE1 . TRP F 1 39  ? -7.905  34.681  63.429  1.00 24.78  ? 39  TRP F NE1 1 
ATOM   16106 C CE2 . TRP F 1 39  ? -8.643  35.832  63.323  1.00 29.94  ? 39  TRP F CE2 1 
ATOM   16107 C CE3 . TRP F 1 39  ? -10.915 36.548  63.736  1.00 27.72  ? 39  TRP F CE3 1 
ATOM   16108 C CZ2 . TRP F 1 39  ? -8.262  37.117  62.901  1.00 25.72  ? 39  TRP F CZ2 1 
ATOM   16109 C CZ3 . TRP F 1 39  ? -10.540 37.818  63.307  1.00 25.29  ? 39  TRP F CZ3 1 
ATOM   16110 C CH2 . TRP F 1 39  ? -9.219  38.086  62.892  1.00 24.96  ? 39  TRP F CH2 1 
ATOM   16111 N N   . HIS F 1 40  ? -12.588 31.679  67.390  1.00 22.64  ? 40  HIS F N   1 
ATOM   16112 C CA  . HIS F 1 40  ? -13.822 31.251  68.037  1.00 26.22  ? 40  HIS F CA  1 
ATOM   16113 C C   . HIS F 1 40  ? -14.091 32.009  69.323  1.00 26.61  ? 40  HIS F C   1 
ATOM   16114 O O   . HIS F 1 40  ? -15.234 32.021  69.782  1.00 27.31  ? 40  HIS F O   1 
ATOM   16115 C CB  . HIS F 1 40  ? -13.795 29.744  68.350  1.00 23.35  ? 40  HIS F CB  1 
ATOM   16116 C CG  . HIS F 1 40  ? -13.984 28.882  67.145  1.00 23.08  ? 40  HIS F CG  1 
ATOM   16117 N ND1 . HIS F 1 40  ? -15.184 28.799  66.473  1.00 25.57  ? 40  HIS F ND1 1 
ATOM   16118 C CD2 . HIS F 1 40  ? -13.114 28.105  66.458  1.00 25.87  ? 40  HIS F CD2 1 
ATOM   16119 C CE1 . HIS F 1 40  ? -15.053 27.989  65.438  1.00 25.28  ? 40  HIS F CE1 1 
ATOM   16120 N NE2 . HIS F 1 40  ? -13.806 27.554  65.406  1.00 29.35  ? 40  HIS F NE2 1 
ATOM   16121 N N   . ALA F 1 41  ? -13.076 32.660  69.887  1.00 27.27  ? 41  ALA F N   1 
ATOM   16122 C CA  . ALA F 1 41  ? -13.149 33.116  71.268  1.00 28.61  ? 41  ALA F CA  1 
ATOM   16123 C C   . ALA F 1 41  ? -14.176 34.230  71.459  1.00 26.55  ? 41  ALA F C   1 
ATOM   16124 O O   . ALA F 1 41  ? -14.356 35.108  70.609  1.00 28.56  ? 41  ALA F O   1 
ATOM   16125 C CB  . ALA F 1 41  ? -11.771 33.587  71.740  1.00 25.38  ? 41  ALA F CB  1 
ATOM   16126 N N   . GLU F 1 42  ? -14.875 34.168  72.578  1.00 28.98  ? 42  GLU F N   1 
ATOM   16127 C CA  . GLU F 1 42  ? -15.562 35.321  73.145  1.00 33.01  ? 42  GLU F CA  1 
ATOM   16128 C C   . GLU F 1 42  ? -15.001 35.534  74.543  1.00 33.63  ? 42  GLU F C   1 
ATOM   16129 O O   . GLU F 1 42  ? -14.190 34.737  75.025  1.00 26.37  ? 42  GLU F O   1 
ATOM   16130 C CB  . GLU F 1 42  ? -17.087 35.134  73.172  1.00 31.79  ? 42  GLU F CB  1 
ATOM   16131 C CG  . GLU F 1 42  ? -17.671 34.772  71.813  1.00 35.44  ? 42  GLU F CG  1 
ATOM   16132 C CD  . GLU F 1 42  ? -18.211 35.979  71.064  1.00 40.97  ? 42  GLU F CD  1 
ATOM   16133 O OE1 . GLU F 1 42  ? -19.043 35.782  70.147  1.00 46.05  ? 42  GLU F OE1 1 
ATOM   16134 O OE2 . GLU F 1 42  ? -17.818 37.121  71.401  1.00 37.93  ? 42  GLU F OE2 1 
ATOM   16135 N N   . ASP F 1 43  ? -15.442 36.632  75.173  1.00 36.83  ? 43  ASP F N   1 
ATOM   16136 C CA  . ASP F 1 43  ? -14.973 37.033  76.497  1.00 35.94  ? 43  ASP F CA  1 
ATOM   16137 C C   . ASP F 1 43  ? -14.930 35.856  77.459  1.00 26.97  ? 43  ASP F C   1 
ATOM   16138 O O   . ASP F 1 43  ? -15.897 35.114  77.587  1.00 32.83  ? 43  ASP F O   1 
ATOM   16139 C CB  . ASP F 1 43  ? -15.888 38.129  77.055  1.00 34.18  ? 43  ASP F CB  1 
ATOM   16140 C CG  . ASP F 1 43  ? -15.546 39.504  76.514  1.00 41.71  ? 43  ASP F CG  1 
ATOM   16141 O OD1 . ASP F 1 43  ? -14.688 39.607  75.606  1.00 39.44  ? 43  ASP F OD1 1 
ATOM   16142 O OD2 . ASP F 1 43  ? -16.147 40.488  76.990  1.00 47.17  ? 43  ASP F OD2 1 
ATOM   16143 N N   . GLY F 1 44  ? -13.799 35.692  78.135  1.00 32.39  ? 44  GLY F N   1 
ATOM   16144 C CA  . GLY F 1 44  ? -13.644 34.667  79.149  1.00 35.74  ? 44  GLY F CA  1 
ATOM   16145 C C   . GLY F 1 44  ? -13.197 33.315  78.636  1.00 35.12  ? 44  GLY F C   1 
ATOM   16146 O O   . GLY F 1 44  ? -12.789 32.471  79.445  1.00 37.74  ? 44  GLY F O   1 
ATOM   16147 N N   . ASP F 1 45  ? -13.229 33.095  77.325  1.00 30.51  ? 45  ASP F N   1 
ATOM   16148 C CA  . ASP F 1 45  ? -12.971 31.773  76.773  1.00 33.50  ? 45  ASP F CA  1 
ATOM   16149 C C   . ASP F 1 45  ? -11.534 31.334  77.017  1.00 37.27  ? 45  ASP F C   1 
ATOM   16150 O O   . ASP F 1 45  ? -10.621 32.141  77.234  1.00 34.08  ? 45  ASP F O   1 
ATOM   16151 C CB  . ASP F 1 45  ? -13.249 31.743  75.272  1.00 30.53  ? 45  ASP F CB  1 
ATOM   16152 C CG  . ASP F 1 45  ? -14.714 31.600  74.967  1.00 30.51  ? 45  ASP F CG  1 
ATOM   16153 O OD1 . ASP F 1 45  ? -15.505 31.404  75.924  1.00 35.58  ? 45  ASP F OD1 1 
ATOM   16154 O OD2 . ASP F 1 45  ? -15.075 31.706  73.780  1.00 29.12  ? 45  ASP F OD2 1 
ATOM   16155 N N   . VAL F 1 46  ? -11.347 30.022  76.953  1.00 33.68  ? 46  VAL F N   1 
ATOM   16156 C CA  . VAL F 1 46  ? -10.051 29.385  77.112  1.00 33.82  ? 46  VAL F CA  1 
ATOM   16157 C C   . VAL F 1 46  ? -9.738  28.649  75.820  1.00 30.88  ? 46  VAL F C   1 
ATOM   16158 O O   . VAL F 1 46  ? -10.583 27.902  75.316  1.00 34.87  ? 46  VAL F O   1 
ATOM   16159 C CB  . VAL F 1 46  ? -10.067 28.419  78.307  1.00 33.45  ? 46  VAL F CB  1 
ATOM   16160 C CG1 . VAL F 1 46  ? -8.847  27.507  78.270  1.00 34.83  ? 46  VAL F CG1 1 
ATOM   16161 C CG2 . VAL F 1 46  ? -10.167 29.208  79.618  1.00 27.40  ? 46  VAL F CG2 1 
ATOM   16162 N N   . LEU F 1 47  ? -8.544  28.866  75.276  1.00 32.42  ? 47  LEU F N   1 
ATOM   16163 C CA  . LEU F 1 47  ? -8.081  28.135  74.102  1.00 32.77  ? 47  LEU F CA  1 
ATOM   16164 C C   . LEU F 1 47  ? -6.899  27.268  74.489  1.00 38.84  ? 47  LEU F C   1 
ATOM   16165 O O   . LEU F 1 47  ? -5.850  27.792  74.886  1.00 37.69  ? 47  LEU F O   1 
ATOM   16166 C CB  . LEU F 1 47  ? -7.674  29.071  72.966  1.00 30.19  ? 47  LEU F CB  1 
ATOM   16167 C CG  . LEU F 1 47  ? -7.046  28.314  71.783  1.00 34.77  ? 47  LEU F CG  1 
ATOM   16168 C CD1 . LEU F 1 47  ? -8.015  27.290  71.170  1.00 32.24  ? 47  LEU F CD1 1 
ATOM   16169 C CD2 . LEU F 1 47  ? -6.487  29.226  70.696  1.00 33.32  ? 47  LEU F CD2 1 
ATOM   16170 N N   . VAL F 1 48  ? -7.059  25.950  74.339  1.00 36.97  ? 48  VAL F N   1 
ATOM   16171 C CA  . VAL F 1 48  ? -5.977  24.989  74.548  1.00 38.33  ? 48  VAL F CA  1 
ATOM   16172 C C   . VAL F 1 48  ? -5.240  24.770  73.230  1.00 37.60  ? 48  VAL F C   1 
ATOM   16173 O O   . VAL F 1 48  ? -5.859  24.440  72.215  1.00 39.84  ? 48  VAL F O   1 
ATOM   16174 C CB  . VAL F 1 48  ? -6.520  23.654  75.090  1.00 35.63  ? 48  VAL F CB  1 
ATOM   16175 C CG1 . VAL F 1 48  ? -5.383  22.726  75.366  1.00 36.93  ? 48  VAL F CG1 1 
ATOM   16176 C CG2 . VAL F 1 48  ? -7.390  23.853  76.347  1.00 27.49  ? 48  VAL F CG2 1 
ATOM   16177 N N   . ILE F 1 49  ? -3.922  24.949  73.233  1.00 38.48  ? 49  ILE F N   1 
ATOM   16178 C CA  . ILE F 1 49  ? -3.134  24.741  72.014  1.00 42.21  ? 49  ILE F CA  1 
ATOM   16179 C C   . ILE F 1 49  ? -1.974  23.791  72.293  1.00 39.91  ? 49  ILE F C   1 
ATOM   16180 O O   . ILE F 1 49  ? -1.350  23.861  73.361  1.00 37.26  ? 49  ILE F O   1 
ATOM   16181 C CB  . ILE F 1 49  ? -2.625  26.073  71.423  1.00 40.21  ? 49  ILE F CB  1 
ATOM   16182 C CG1 . ILE F 1 49  ? -1.348  26.572  72.100  1.00 41.83  ? 49  ILE F CG1 1 
ATOM   16183 C CG2 . ILE F 1 49  ? -3.665  27.151  71.505  1.00 44.70  ? 49  ILE F CG2 1 
ATOM   16184 C CD1 . ILE F 1 49  ? -0.505  27.439  71.170  1.00 44.34  ? 49  ILE F CD1 1 
ATOM   16185 N N   . PRO F 1 50  ? -1.677  22.864  71.386  1.00 40.77  ? 50  PRO F N   1 
ATOM   16186 C CA  . PRO F 1 50  ? -0.538  21.955  71.577  1.00 45.03  ? 50  PRO F CA  1 
ATOM   16187 C C   . PRO F 1 50  ? 0.798   22.475  71.068  1.00 45.48  ? 50  PRO F C   1 
ATOM   16188 O O   . PRO F 1 50  ? 1.815   21.806  71.292  1.00 42.84  ? 50  PRO F O   1 
ATOM   16189 C CB  . PRO F 1 50  ? -0.971  20.714  70.775  1.00 42.75  ? 50  PRO F CB  1 
ATOM   16190 C CG  . PRO F 1 50  ? -1.848  21.256  69.700  1.00 41.67  ? 50  PRO F CG  1 
ATOM   16191 C CD  . PRO F 1 50  ? -2.576  22.420  70.307  1.00 39.25  ? 50  PRO F CD  1 
ATOM   16192 N N   . ASP F 1 51  ? 0.819   23.642  70.411  1.00 44.64  ? 51  ASP F N   1 
ATOM   16193 C CA  . ASP F 1 51  ? 2.001   24.135  69.707  1.00 45.58  ? 51  ASP F CA  1 
ATOM   16194 C C   . ASP F 1 51  ? 2.373   25.562  70.103  1.00 46.50  ? 51  ASP F C   1 
ATOM   16195 O O   . ASP F 1 51  ? 2.219   25.956  71.266  1.00 44.66  ? 51  ASP F O   1 
ATOM   16196 C CB  . ASP F 1 51  ? 1.772   24.033  68.193  1.00 45.44  ? 51  ASP F CB  1 
ATOM   16197 C CG  . ASP F 1 51  ? 0.368   24.457  67.781  1.00 44.55  ? 51  ASP F CG  1 
ATOM   16198 O OD1 . ASP F 1 51  ? -0.469  24.725  68.681  1.00 42.47  ? 51  ASP F OD1 1 
ATOM   16199 O OD2 . ASP F 1 51  ? 0.085   24.456  66.560  1.00 35.47  ? 51  ASP F OD2 1 
ATOM   16200 N N   . THR F 1 52  ? 2.897   26.333  69.157  1.00 46.74  ? 52  THR F N   1 
ATOM   16201 C CA  . THR F 1 52  ? 3.278   27.713  69.425  1.00 51.28  ? 52  THR F CA  1 
ATOM   16202 C C   . THR F 1 52  ? 2.197   28.633  68.888  1.00 47.67  ? 52  THR F C   1 
ATOM   16203 O O   . THR F 1 52  ? 1.320   28.222  68.131  1.00 50.43  ? 52  THR F O   1 
ATOM   16204 C CB  . THR F 1 52  ? 4.624   28.077  68.783  1.00 51.68  ? 52  THR F CB  1 
ATOM   16205 O OG1 . THR F 1 52  ? 4.393   28.548  67.450  1.00 57.80  ? 52  THR F OG1 1 
ATOM   16206 C CG2 . THR F 1 52  ? 5.575   26.872  68.733  1.00 46.82  ? 52  THR F CG2 1 
ATOM   16207 N N   . VAL F 1 53  ? 2.263   29.895  69.277  1.00 44.75  ? 53  VAL F N   1 
ATOM   16208 C CA  . VAL F 1 53  ? 1.254   30.812  68.772  1.00 44.97  ? 53  VAL F CA  1 
ATOM   16209 C C   . VAL F 1 53  ? 1.931   32.054  68.218  1.00 48.44  ? 53  VAL F C   1 
ATOM   16210 O O   . VAL F 1 53  ? 1.989   32.229  66.992  1.00 50.81  ? 53  VAL F O   1 
ATOM   16211 C CB  . VAL F 1 53  ? 0.201   31.159  69.846  1.00 49.12  ? 53  VAL F CB  1 
ATOM   16212 C CG1 . VAL F 1 53  ? 0.846   31.515  71.206  1.00 49.29  ? 53  VAL F CG1 1 
ATOM   16213 C CG2 . VAL F 1 53  ? -0.729  32.261  69.337  1.00 44.16  ? 53  VAL F CG2 1 
ATOM   16214 N N   . ASP F 1 54  ? 2.515   32.862  69.115  1.00 38.38  ? 54  ASP F N   1 
ATOM   16215 C CA  . ASP F 1 54  ? 2.908   34.266  68.982  1.00 44.11  ? 54  ASP F CA  1 
ATOM   16216 C C   . ASP F 1 54  ? 2.120   35.030  70.036  1.00 42.14  ? 54  ASP F C   1 
ATOM   16217 O O   . ASP F 1 54  ? 0.883   35.070  69.975  1.00 41.34  ? 54  ASP F O   1 
ATOM   16218 C CB  . ASP F 1 54  ? 2.637   34.854  67.592  1.00 41.64  ? 54  ASP F CB  1 
ATOM   16219 C CG  . ASP F 1 54  ? 3.152   36.277  67.435  1.00 44.76  ? 54  ASP F CG  1 
ATOM   16220 O OD1 . ASP F 1 54  ? 3.205   37.021  68.442  1.00 39.40  ? 54  ASP F OD1 1 
ATOM   16221 O OD2 . ASP F 1 54  ? 3.505   36.650  66.288  1.00 39.22  ? 54  ASP F OD2 1 
ATOM   16222 N N   . PRO F 1 55  ? 2.787   35.656  71.006  1.00 46.51  ? 55  PRO F N   1 
ATOM   16223 C CA  . PRO F 1 55  ? 2.035   36.288  72.099  1.00 43.81  ? 55  PRO F CA  1 
ATOM   16224 C C   . PRO F 1 55  ? 1.168   37.427  71.623  1.00 38.05  ? 55  PRO F C   1 
ATOM   16225 O O   . PRO F 1 55  ? 0.202   37.767  72.314  1.00 42.80  ? 55  PRO F O   1 
ATOM   16226 C CB  . PRO F 1 55  ? 3.123   36.777  73.069  1.00 44.99  ? 55  PRO F CB  1 
ATOM   16227 C CG  . PRO F 1 55  ? 4.451   36.432  72.443  1.00 47.15  ? 55  PRO F CG  1 
ATOM   16228 C CD  . PRO F 1 55  ? 4.233   35.941  71.054  1.00 45.94  ? 55  PRO F CD  1 
ATOM   16229 N N   . ASP F 1 56  ? 1.468   38.015  70.458  1.00 36.85  ? 56  ASP F N   1 
ATOM   16230 C CA  . ASP F 1 56  ? 0.649   39.096  69.914  1.00 42.17  ? 56  ASP F CA  1 
ATOM   16231 C C   . ASP F 1 56  ? -0.618  38.614  69.214  1.00 37.36  ? 56  ASP F C   1 
ATOM   16232 O O   . ASP F 1 56  ? -1.562  39.394  69.074  1.00 34.18  ? 56  ASP F O   1 
ATOM   16233 C CB  . ASP F 1 56  ? 1.473   39.932  68.934  1.00 41.24  ? 56  ASP F CB  1 
ATOM   16234 C CG  . ASP F 1 56  ? 2.312   40.981  69.635  1.00 43.91  ? 56  ASP F CG  1 
ATOM   16235 O OD1 . ASP F 1 56  ? 2.657   40.754  70.824  1.00 48.56  ? 56  ASP F OD1 1 
ATOM   16236 O OD2 . ASP F 1 56  ? 2.653   42.006  68.996  1.00 37.39  ? 56  ASP F OD2 1 
ATOM   16237 N N   . PHE F 1 57  ? -0.664  37.366  68.755  1.00 35.07  ? 57  PHE F N   1 
ATOM   16238 C CA  . PHE F 1 57  ? -1.846  36.866  68.054  1.00 32.53  ? 57  PHE F CA  1 
ATOM   16239 C C   . PHE F 1 57  ? -3.144  37.041  68.833  1.00 33.23  ? 57  PHE F C   1 
ATOM   16240 O O   . PHE F 1 57  ? -4.129  37.496  68.231  1.00 33.36  ? 57  PHE F O   1 
ATOM   16241 C CB  . PHE F 1 57  ? -1.633  35.394  67.672  1.00 33.42  ? 57  PHE F CB  1 
ATOM   16242 C CG  . PHE F 1 57  ? -2.160  35.039  66.327  1.00 34.46  ? 57  PHE F CG  1 
ATOM   16243 C CD1 . PHE F 1 57  ? -3.449  35.380  65.963  1.00 36.75  ? 57  PHE F CD1 1 
ATOM   16244 C CD2 . PHE F 1 57  ? -1.379  34.344  65.429  1.00 39.86  ? 57  PHE F CD2 1 
ATOM   16245 C CE1 . PHE F 1 57  ? -3.951  35.053  64.726  1.00 32.15  ? 57  PHE F CE1 1 
ATOM   16246 C CE2 . PHE F 1 57  ? -1.881  34.004  64.179  1.00 41.41  ? 57  PHE F CE2 1 
ATOM   16247 C CZ  . PHE F 1 57  ? -3.176  34.367  63.830  1.00 34.99  ? 57  PHE F CZ  1 
ATOM   16248 N N   . PRO F 1 58  ? -3.236  36.701  70.127  1.00 29.80  ? 58  PRO F N   1 
ATOM   16249 C CA  . PRO F 1 58  ? -4.525  36.901  70.832  1.00 33.14  ? 58  PRO F CA  1 
ATOM   16250 C C   . PRO F 1 58  ? -5.067  38.322  70.771  1.00 30.58  ? 58  PRO F C   1 
ATOM   16251 O O   . PRO F 1 58  ? -6.243  38.524  70.421  1.00 29.60  ? 58  PRO F O   1 
ATOM   16252 C CB  . PRO F 1 58  ? -4.199  36.479  72.272  1.00 31.62  ? 58  PRO F CB  1 
ATOM   16253 C CG  . PRO F 1 58  ? -3.092  35.467  72.109  1.00 34.63  ? 58  PRO F CG  1 
ATOM   16254 C CD  . PRO F 1 58  ? -2.265  35.975  70.966  1.00 31.01  ? 58  PRO F CD  1 
ATOM   16255 N N   . GLY F 1 59  ? -4.248  39.315  71.127  1.00 31.45  ? 59  GLY F N   1 
ATOM   16256 C CA  . GLY F 1 59  ? -4.731  40.683  71.142  1.00 25.41  ? 59  GLY F CA  1 
ATOM   16257 C C   . GLY F 1 59  ? -5.170  41.152  69.767  1.00 28.04  ? 59  GLY F C   1 
ATOM   16258 O O   . GLY F 1 59  ? -6.172  41.865  69.630  1.00 27.19  ? 59  GLY F O   1 
ATOM   16259 N N   . TYR F 1 60  ? -4.424  40.764  68.732  1.00 25.72  ? 60  TYR F N   1 
ATOM   16260 C CA  . TYR F 1 60  ? -4.810  41.105  67.370  1.00 23.88  ? 60  TYR F CA  1 
ATOM   16261 C C   . TYR F 1 60  ? -6.196  40.562  67.044  1.00 26.07  ? 60  TYR F C   1 
ATOM   16262 O O   . TYR F 1 60  ? -7.071  41.309  66.584  1.00 26.91  ? 60  TYR F O   1 
ATOM   16263 C CB  . TYR F 1 60  ? -3.775  40.589  66.384  1.00 19.17  ? 60  TYR F CB  1 
ATOM   16264 C CG  . TYR F 1 60  ? -4.302  40.401  64.979  1.00 21.31  ? 60  TYR F CG  1 
ATOM   16265 C CD1 . TYR F 1 60  ? -4.591  41.480  64.170  1.00 20.63  ? 60  TYR F CD1 1 
ATOM   16266 C CD2 . TYR F 1 60  ? -4.504  39.130  64.460  1.00 23.13  ? 60  TYR F CD2 1 
ATOM   16267 C CE1 . TYR F 1 60  ? -5.070  41.299  62.881  1.00 20.76  ? 60  TYR F CE1 1 
ATOM   16268 C CE2 . TYR F 1 60  ? -4.976  38.944  63.189  1.00 21.41  ? 60  TYR F CE2 1 
ATOM   16269 C CZ  . TYR F 1 60  ? -5.256  40.020  62.395  1.00 24.27  ? 60  TYR F CZ  1 
ATOM   16270 O OH  . TYR F 1 60  ? -5.739  39.798  61.111  1.00 23.57  ? 60  TYR F OH  1 
ATOM   16271 N N   . VAL F 1 61  ? -6.422  39.267  67.299  1.00 28.42  ? 61  VAL F N   1 
ATOM   16272 C CA  . VAL F 1 61  ? -7.748  38.670  67.101  1.00 27.67  ? 61  VAL F CA  1 
ATOM   16273 C C   . VAL F 1 61  ? -8.797  39.422  67.912  1.00 26.99  ? 61  VAL F C   1 
ATOM   16274 O O   . VAL F 1 61  ? -9.876  39.765  67.408  1.00 28.81  ? 61  VAL F O   1 
ATOM   16275 C CB  . VAL F 1 61  ? -7.737  37.180  67.489  1.00 29.82  ? 61  VAL F CB  1 
ATOM   16276 C CG1 . VAL F 1 61  ? -9.178  36.627  67.492  1.00 24.62  ? 61  VAL F CG1 1 
ATOM   16277 C CG2 . VAL F 1 61  ? -6.809  36.370  66.587  1.00 31.78  ? 61  VAL F CG2 1 
ATOM   16278 N N   . ALA F 1 62  ? -8.495  39.672  69.191  1.00 28.58  ? 62  ALA F N   1 
ATOM   16279 C CA  . ALA F 1 62  ? -9.417  40.394  70.069  1.00 27.46  ? 62  ALA F CA  1 
ATOM   16280 C C   . ALA F 1 62  ? -9.736  41.790  69.530  1.00 33.50  ? 62  ALA F C   1 
ATOM   16281 O O   . ALA F 1 62  ? -10.900 42.209  69.525  1.00 33.77  ? 62  ALA F O   1 
ATOM   16282 C CB  . ALA F 1 62  ? -8.821  40.490  71.473  1.00 27.54  ? 62  ALA F CB  1 
ATOM   16283 N N   . ASP F 1 63  ? -8.705  42.541  69.109  1.00 29.21  ? 63  ASP F N   1 
ATOM   16284 C CA  . ASP F 1 63  ? -8.921  43.833  68.458  1.00 27.96  ? 63  ASP F CA  1 
ATOM   16285 C C   . ASP F 1 63  ? -9.855  43.683  67.277  1.00 28.67  ? 63  ASP F C   1 
ATOM   16286 O O   . ASP F 1 63  ? -10.795 44.462  67.103  1.00 26.36  ? 63  ASP F O   1 
ATOM   16287 C CB  . ASP F 1 63  ? -7.602  44.410  67.939  1.00 30.39  ? 63  ASP F CB  1 
ATOM   16288 C CG  . ASP F 1 63  ? -6.669  44.840  69.036  1.00 30.90  ? 63  ASP F CG  1 
ATOM   16289 O OD1 . ASP F 1 63  ? -7.084  44.866  70.210  1.00 35.80  ? 63  ASP F OD1 1 
ATOM   16290 O OD2 . ASP F 1 63  ? -5.499  45.124  68.707  1.00 32.36  ? 63  ASP F OD2 1 
ATOM   16291 N N   . THR F 1 64  ? -9.578  42.694  66.428  1.00 26.11  ? 64  THR F N   1 
ATOM   16292 C CA  . THR F 1 64  ? -10.316 42.567  65.182  1.00 28.75  ? 64  THR F CA  1 
ATOM   16293 C C   . THR F 1 64  ? -11.760 42.144  65.410  1.00 29.72  ? 64  THR F C   1 
ATOM   16294 O O   . THR F 1 64  ? -12.648 42.555  64.656  1.00 31.21  ? 64  THR F O   1 
ATOM   16295 C CB  . THR F 1 64  ? -9.619  41.561  64.286  1.00 30.34  ? 64  THR F CB  1 
ATOM   16296 O OG1 . THR F 1 64  ? -8.256  41.976  64.104  1.00 34.87  ? 64  THR F OG1 1 
ATOM   16297 C CG2 . THR F 1 64  ? -10.321 41.491  62.954  1.00 26.99  ? 64  THR F CG2 1 
ATOM   16298 N N   . LEU F 1 65  ? -12.009 41.314  66.420  1.00 30.46  ? 65  LEU F N   1 
ATOM   16299 C CA  . LEU F 1 65  ? -13.352 40.819  66.706  1.00 35.98  ? 65  LEU F CA  1 
ATOM   16300 C C   . LEU F 1 65  ? -14.152 41.740  67.614  1.00 36.06  ? 65  LEU F C   1 
ATOM   16301 O O   . LEU F 1 65  ? -15.385 41.682  67.591  1.00 40.88  ? 65  LEU F O   1 
ATOM   16302 C CB  . LEU F 1 65  ? -13.287 39.431  67.353  1.00 30.48  ? 65  LEU F CB  1 
ATOM   16303 C CG  . LEU F 1 65  ? -13.077 38.259  66.395  1.00 33.57  ? 65  LEU F CG  1 
ATOM   16304 C CD1 . LEU F 1 65  ? -12.816 36.983  67.183  1.00 28.58  ? 65  LEU F CD1 1 
ATOM   16305 C CD2 . LEU F 1 65  ? -14.279 38.080  65.469  1.00 27.74  ? 65  LEU F CD2 1 
ATOM   16306 N N   . GLY F 1 66  ? -13.485 42.573  68.414  1.00 39.48  ? 66  GLY F N   1 
ATOM   16307 C CA  . GLY F 1 66  ? -14.159 43.530  69.273  1.00 38.85  ? 66  GLY F CA  1 
ATOM   16308 C C   . GLY F 1 66  ? -14.517 42.981  70.638  1.00 36.62  ? 66  GLY F C   1 
ATOM   16309 O O   . GLY F 1 66  ? -15.564 43.317  71.199  1.00 46.07  ? 66  GLY F O   1 
ATOM   16310 N N   . ILE F 1 67  ? -13.653 42.137  71.188  1.00 39.06  ? 67  ILE F N   1 
ATOM   16311 C CA  . ILE F 1 67  ? -13.895 41.534  72.491  1.00 37.75  ? 67  ILE F CA  1 
ATOM   16312 C C   . ILE F 1 67  ? -12.772 41.951  73.428  1.00 38.92  ? 67  ILE F C   1 
ATOM   16313 O O   . ILE F 1 67  ? -11.825 42.631  73.016  1.00 40.63  ? 67  ILE F O   1 
ATOM   16314 C CB  . ILE F 1 67  ? -14.003 39.998  72.391  1.00 41.79  ? 67  ILE F CB  1 
ATOM   16315 C CG1 . ILE F 1 67  ? -12.703 39.402  71.842  1.00 36.63  ? 67  ILE F CG1 1 
ATOM   16316 C CG2 . ILE F 1 67  ? -15.178 39.590  71.501  1.00 41.23  ? 67  ILE F CG2 1 
ATOM   16317 C CD1 . ILE F 1 67  ? -12.665 37.884  71.855  1.00 35.94  ? 67  ILE F CD1 1 
ATOM   16318 N N   . ASP F 1 68  ? -12.869 41.549  74.694  1.00 41.27  ? 68  ASP F N   1 
ATOM   16319 C CA  . ASP F 1 68  ? -11.840 41.849  75.687  1.00 44.00  ? 68  ASP F CA  1 
ATOM   16320 C C   . ASP F 1 68  ? -10.755 40.782  75.592  1.00 40.41  ? 68  ASP F C   1 
ATOM   16321 O O   . ASP F 1 68  ? -10.906 39.674  76.114  1.00 44.49  ? 68  ASP F O   1 
ATOM   16322 C CB  . ASP F 1 68  ? -12.441 41.923  77.090  1.00 42.03  ? 68  ASP F CB  1 
ATOM   16323 C CG  . ASP F 1 68  ? -11.425 42.321  78.131  1.00 40.26  ? 68  ASP F CG  1 
ATOM   16324 O OD1 . ASP F 1 68  ? -10.244 42.470  77.769  1.00 42.63  ? 68  ASP F OD1 1 
ATOM   16325 O OD2 . ASP F 1 68  ? -11.799 42.503  79.307  1.00 49.72  ? 68  ASP F OD2 1 
ATOM   16326 N N   . GLY F 1 69  ? -9.638  41.132  74.952  1.00 44.18  ? 69  GLY F N   1 
ATOM   16327 C CA  . GLY F 1 69  ? -8.514  40.217  74.900  1.00 41.85  ? 69  GLY F CA  1 
ATOM   16328 C C   . GLY F 1 69  ? -7.967  39.857  76.265  1.00 46.14  ? 69  GLY F C   1 
ATOM   16329 O O   . GLY F 1 69  ? -7.505  38.729  76.475  1.00 41.36  ? 69  GLY F O   1 
ATOM   16330 N N   . THR F 1 70  ? -8.018  40.794  77.218  1.00 42.05  ? 70  THR F N   1 
ATOM   16331 C CA  . THR F 1 70  ? -7.470  40.497  78.535  1.00 41.09  ? 70  THR F CA  1 
ATOM   16332 C C   . THR F 1 70  ? -8.198  39.329  79.183  1.00 41.72  ? 70  THR F C   1 
ATOM   16333 O O   . THR F 1 70  ? -7.628  38.664  80.055  1.00 47.41  ? 70  THR F O   1 
ATOM   16334 C CB  . THR F 1 70  ? -7.514  41.753  79.429  1.00 41.86  ? 70  THR F CB  1 
ATOM   16335 O OG1 . THR F 1 70  ? -8.866  42.061  79.800  1.00 37.77  ? 70  THR F OG1 1 
ATOM   16336 C CG2 . THR F 1 70  ? -6.935  42.953  78.688  1.00 34.19  ? 70  THR F CG2 1 
ATOM   16337 N N   . SER F 1 71  ? -9.427  39.043  78.742  1.00 45.75  ? 71  SER F N   1 
ATOM   16338 C CA  . SER F 1 71  ? -10.255 37.971  79.283  1.00 44.39  ? 71  SER F CA  1 
ATOM   16339 C C   . SER F 1 71  ? -10.101 36.655  78.539  1.00 42.44  ? 71  SER F C   1 
ATOM   16340 O O   . SER F 1 71  ? -10.659 35.651  78.990  1.00 47.68  ? 71  SER F O   1 
ATOM   16341 C CB  . SER F 1 71  ? -11.740 38.374  79.264  1.00 36.88  ? 71  SER F CB  1 
ATOM   16342 O OG  . SER F 1 71  ? -12.228 38.415  77.930  1.00 37.07  ? 71  SER F OG  1 
ATOM   16343 N N   . VAL F 1 72  ? -9.367  36.624  77.430  1.00 43.14  ? 72  VAL F N   1 
ATOM   16344 C CA  . VAL F 1 72  ? -9.182  35.403  76.651  1.00 39.41  ? 72  VAL F CA  1 
ATOM   16345 C C   . VAL F 1 72  ? -7.892  34.730  77.106  1.00 39.89  ? 72  VAL F C   1 
ATOM   16346 O O   . VAL F 1 72  ? -6.819  35.335  77.072  1.00 38.61  ? 72  VAL F O   1 
ATOM   16347 C CB  . VAL F 1 72  ? -9.158  35.705  75.144  1.00 34.54  ? 72  VAL F CB  1 
ATOM   16348 C CG1 . VAL F 1 72  ? -8.333  34.674  74.379  1.00 36.87  ? 72  VAL F CG1 1 
ATOM   16349 C CG2 . VAL F 1 72  ? -10.566 35.728  74.615  1.00 40.22  ? 72  VAL F CG2 1 
ATOM   16350 N N   . HIS F 1 73  ? -7.994  33.475  77.531  1.00 39.53  ? 73  HIS F N   1 
ATOM   16351 C CA  . HIS F 1 73  ? -6.882  32.754  78.133  1.00 38.08  ? 73  HIS F CA  1 
ATOM   16352 C C   . HIS F 1 73  ? -6.387  31.668  77.184  1.00 41.63  ? 73  HIS F C   1 
ATOM   16353 O O   . HIS F 1 73  ? -7.184  30.974  76.543  1.00 40.68  ? 73  HIS F O   1 
ATOM   16354 C CB  . HIS F 1 73  ? -7.302  32.146  79.477  1.00 38.72  ? 73  HIS F CB  1 
ATOM   16355 C CG  . HIS F 1 73  ? -7.736  33.168  80.489  1.00 46.80  ? 73  HIS F CG  1 
ATOM   16356 N ND1 . HIS F 1 73  ? -9.057  33.374  80.825  1.00 47.23  ? 73  HIS F ND1 1 
ATOM   16357 C CD2 . HIS F 1 73  ? -7.022  34.049  81.230  1.00 48.64  ? 73  HIS F CD2 1 
ATOM   16358 C CE1 . HIS F 1 73  ? -9.139  34.336  81.728  1.00 44.62  ? 73  HIS F CE1 1 
ATOM   16359 N NE2 . HIS F 1 73  ? -7.917  34.760  81.993  1.00 47.44  ? 73  HIS F NE2 1 
ATOM   16360 N N   . VAL F 1 74  ? -5.070  31.533  77.085  1.00 38.25  ? 74  VAL F N   1 
ATOM   16361 C CA  . VAL F 1 74  ? -4.438  30.558  76.205  1.00 38.42  ? 74  VAL F CA  1 
ATOM   16362 C C   . VAL F 1 74  ? -3.647  29.587  77.072  1.00 42.71  ? 74  VAL F C   1 
ATOM   16363 O O   . VAL F 1 74  ? -2.607  29.955  77.629  1.00 46.90  ? 74  VAL F O   1 
ATOM   16364 C CB  . VAL F 1 74  ? -3.530  31.235  75.175  1.00 45.19  ? 74  VAL F CB  1 
ATOM   16365 C CG1 . VAL F 1 74  ? -2.688  30.205  74.439  1.00 40.64  ? 74  VAL F CG1 1 
ATOM   16366 C CG2 . VAL F 1 74  ? -4.363  32.081  74.236  1.00 33.66  ? 74  VAL F CG2 1 
ATOM   16367 N N   . GLU F 1 75  ? -4.130  28.345  77.174  1.00 46.08  ? 75  GLU F N   1 
ATOM   16368 C CA  . GLU F 1 75  ? -3.484  27.280  77.939  1.00 40.59  ? 75  GLU F CA  1 
ATOM   16369 C C   . GLU F 1 75  ? -2.659  26.416  76.986  1.00 42.77  ? 75  GLU F C   1 
ATOM   16370 O O   . GLU F 1 75  ? -3.211  25.721  76.127  1.00 45.85  ? 75  GLU F O   1 
ATOM   16371 C CB  . GLU F 1 75  ? -4.539  26.451  78.669  1.00 45.20  ? 75  GLU F CB  1 
ATOM   16372 C CG  . GLU F 1 75  ? -4.057  25.719  79.913  1.00 49.32  ? 75  GLU F CG  1 
ATOM   16373 C CD  . GLU F 1 75  ? -3.415  26.633  80.934  1.00 53.83  ? 75  GLU F CD  1 
ATOM   16374 O OE1 . GLU F 1 75  ? -3.896  27.780  81.101  1.00 50.95  ? 75  GLU F OE1 1 
ATOM   16375 O OE2 . GLU F 1 75  ? -2.425  26.199  81.566  1.00 54.53  ? 75  GLU F OE2 1 
ATOM   16376 N N   . ARG F 1 76  ? -1.340  26.445  77.138  1.00 41.66  ? 76  ARG F N   1 
ATOM   16377 C CA  . ARG F 1 76  ? -0.435  25.768  76.218  1.00 37.67  ? 76  ARG F CA  1 
ATOM   16378 C C   . ARG F 1 76  ? -0.074  24.396  76.763  1.00 41.50  ? 76  ARG F C   1 
ATOM   16379 O O   . ARG F 1 76  ? 0.492   24.288  77.858  1.00 44.30  ? 76  ARG F O   1 
ATOM   16380 C CB  . ARG F 1 76  ? 0.833   26.597  76.001  1.00 41.62  ? 76  ARG F CB  1 
ATOM   16381 C CG  . ARG F 1 76  ? 0.620   27.867  75.214  1.00 42.04  ? 76  ARG F CG  1 
ATOM   16382 C CD  . ARG F 1 76  ? 1.954   28.464  74.796  1.00 49.13  ? 76  ARG F CD  1 
ATOM   16383 N NE  . ARG F 1 76  ? 1.915   29.878  74.422  1.00 59.74  ? 76  ARG F NE  1 
ATOM   16384 C CZ  . ARG F 1 76  ? 1.265   30.852  75.054  1.00 62.99  ? 76  ARG F CZ  1 
ATOM   16385 N NH1 . ARG F 1 76  ? 0.634   30.649  76.206  1.00 56.01  ? 76  ARG F NH1 1 
ATOM   16386 N NH2 . ARG F 1 76  ? 1.260   32.073  74.521  1.00 62.79  ? 76  ARG F NH2 1 
ATOM   16387 N N   . THR F 1 77  ? -0.401  23.354  76.011  1.00 41.58  ? 77  THR F N   1 
ATOM   16388 C CA  . THR F 1 77  ? 0.056   22.011  76.336  1.00 44.34  ? 77  THR F CA  1 
ATOM   16389 C C   . THR F 1 77  ? 1.305   21.711  75.528  1.00 44.90  ? 77  THR F C   1 
ATOM   16390 O O   . THR F 1 77  ? 1.505   22.238  74.428  1.00 50.92  ? 77  THR F O   1 
ATOM   16391 C CB  . THR F 1 77  ? -0.998  20.934  76.052  1.00 36.80  ? 77  THR F CB  1 
ATOM   16392 O OG1 . THR F 1 77  ? -1.086  20.722  74.643  1.00 31.78  ? 77  THR F OG1 1 
ATOM   16393 C CG2 . THR F 1 77  ? -2.362  21.320  76.604  1.00 36.51  ? 77  THR F CG2 1 
ATOM   16394 N N   . GLN F 1 78  ? 2.151   20.859  76.082  1.00 41.39  ? 78  GLN F N   1 
ATOM   16395 C CA  . GLN F 1 78  ? 3.413   20.594  75.415  1.00 49.06  ? 78  GLN F CA  1 
ATOM   16396 C C   . GLN F 1 78  ? 3.259   19.584  74.286  1.00 50.02  ? 78  GLN F C   1 
ATOM   16397 O O   . GLN F 1 78  ? 4.133   19.504  73.418  1.00 48.57  ? 78  GLN F O   1 
ATOM   16398 C CB  . GLN F 1 78  ? 4.444   20.124  76.449  1.00 54.85  ? 78  GLN F CB  1 
ATOM   16399 C CG  . GLN F 1 78  ? 4.561   21.051  77.682  1.00 50.25  ? 78  GLN F CG  1 
ATOM   16400 C CD  . GLN F 1 78  ? 3.510   20.763  78.766  1.00 63.77  ? 78  GLN F CD  1 
ATOM   16401 O OE1 . GLN F 1 78  ? 2.324   21.068  78.593  1.00 56.14  ? 78  GLN F OE1 1 
ATOM   16402 N NE2 . GLN F 1 78  ? 3.949   20.195  79.895  1.00 67.22  ? 78  GLN F NE2 1 
ATOM   16403 N N   . THR F 1 79  ? 2.152   18.854  74.253  1.00 48.90  ? 79  THR F N   1 
ATOM   16404 C CA  . THR F 1 79  ? 1.952   17.716  73.373  1.00 46.60  ? 79  THR F CA  1 
ATOM   16405 C C   . THR F 1 79  ? 0.629   17.842  72.637  1.00 42.89  ? 79  THR F C   1 
ATOM   16406 O O   . THR F 1 79  ? -0.227  18.640  73.014  1.00 39.03  ? 79  THR F O   1 
ATOM   16407 C CB  . THR F 1 79  ? 1.957   16.418  74.191  1.00 43.09  ? 79  THR F CB  1 
ATOM   16408 O OG1 . THR F 1 79  ? 1.322   16.666  75.456  1.00 37.89  ? 79  THR F OG1 1 
ATOM   16409 C CG2 . THR F 1 79  ? 3.389   15.912  74.382  1.00 50.67  ? 79  THR F CG2 1 
ATOM   16410 N N   . PRO F 1 80  ? 0.430   17.039  71.590  1.00 43.97  ? 80  PRO F N   1 
ATOM   16411 C CA  . PRO F 1 80  ? -0.881  17.016  70.932  1.00 38.98  ? 80  PRO F CA  1 
ATOM   16412 C C   . PRO F 1 80  ? -1.981  16.603  71.894  1.00 35.67  ? 80  PRO F C   1 
ATOM   16413 O O   . PRO F 1 80  ? -1.748  15.970  72.926  1.00 39.23  ? 80  PRO F O   1 
ATOM   16414 C CB  . PRO F 1 80  ? -0.698  15.989  69.808  1.00 39.82  ? 80  PRO F CB  1 
ATOM   16415 C CG  . PRO F 1 80  ? 0.766   16.025  69.509  1.00 33.93  ? 80  PRO F CG  1 
ATOM   16416 C CD  . PRO F 1 80  ? 1.431   16.255  70.843  1.00 40.84  ? 80  PRO F CD  1 
ATOM   16417 N N   . LEU F 1 81  ? -3.204  16.986  71.546  1.00 38.66  ? 81  LEU F N   1 
ATOM   16418 C CA  . LEU F 1 81  ? -4.336  16.882  72.464  1.00 34.24  ? 81  LEU F CA  1 
ATOM   16419 C C   . LEU F 1 81  ? -4.987  15.502  72.379  1.00 36.25  ? 81  LEU F C   1 
ATOM   16420 O O   . LEU F 1 81  ? -6.189  15.360  72.154  1.00 32.52  ? 81  LEU F O   1 
ATOM   16421 C CB  . LEU F 1 81  ? -5.346  17.982  72.172  1.00 33.52  ? 81  LEU F CB  1 
ATOM   16422 C CG  . LEU F 1 81  ? -4.907  19.378  72.593  1.00 41.34  ? 81  LEU F CG  1 
ATOM   16423 C CD1 . LEU F 1 81  ? -6.103  20.315  72.579  1.00 34.20  ? 81  LEU F CD1 1 
ATOM   16424 C CD2 . LEU F 1 81  ? -4.208  19.337  73.965  1.00 35.29  ? 81  LEU F CD2 1 
ATOM   16425 N N   . SER F 1 82  ? -4.165  14.477  72.590  1.00 31.89  ? 82  SER F N   1 
ATOM   16426 C CA  . SER F 1 82  ? -4.624  13.098  72.503  1.00 32.51  ? 82  SER F CA  1 
ATOM   16427 C C   . SER F 1 82  ? -5.615  12.783  73.626  1.00 35.09  ? 82  SER F C   1 
ATOM   16428 O O   . SER F 1 82  ? -5.906  13.607  74.506  1.00 37.17  ? 82  SER F O   1 
ATOM   16429 C CB  . SER F 1 82  ? -3.426  12.150  72.548  1.00 34.29  ? 82  SER F CB  1 
ATOM   16430 O OG  . SER F 1 82  ? -2.846  12.158  73.839  1.00 33.05  ? 82  SER F OG  1 
ATOM   16431 N N   . GLU F 1 83  ? -6.151  11.562  73.592  1.00 35.98  ? 83  GLU F N   1 
ATOM   16432 C CA  . GLU F 1 83  ? -7.048  11.140  74.658  1.00 31.25  ? 83  GLU F CA  1 
ATOM   16433 C C   . GLU F 1 83  ? -6.310  11.096  75.990  1.00 36.95  ? 83  GLU F C   1 
ATOM   16434 O O   . GLU F 1 83  ? -6.869  11.463  77.030  1.00 31.10  ? 83  GLU F O   1 
ATOM   16435 C CB  . GLU F 1 83  ? -7.672  9.778   74.329  1.00 38.31  ? 83  GLU F CB  1 
ATOM   16436 C CG  . GLU F 1 83  ? -8.646  9.755   73.103  1.00 31.69  ? 83  GLU F CG  1 
ATOM   16437 C CD  . GLU F 1 83  ? -9.979  10.464  73.365  1.00 37.04  ? 83  GLU F CD  1 
ATOM   16438 O OE1 . GLU F 1 83  ? -9.997  11.706  73.252  1.00 32.73  ? 83  GLU F OE1 1 
ATOM   16439 O OE2 . GLU F 1 83  ? -11.008 9.797   73.671  1.00 36.87  ? 83  GLU F OE2 1 
ATOM   16440 N N   . ALA F 1 84  ? -5.036  10.694  75.981  1.00 34.16  ? 84  ALA F N   1 
ATOM   16441 C CA  . ALA F 1 84  ? -4.321  10.592  77.249  1.00 32.06  ? 84  ALA F CA  1 
ATOM   16442 C C   . ALA F 1 84  ? -4.135  11.971  77.873  1.00 32.73  ? 84  ALA F C   1 
ATOM   16443 O O   . ALA F 1 84  ? -4.372  12.157  79.073  1.00 36.20  ? 84  ALA F O   1 
ATOM   16444 C CB  . ALA F 1 84  ? -2.984  9.877   77.054  1.00 22.76  ? 84  ALA F CB  1 
ATOM   16445 N N   . VAL F 1 85  ? -3.757  12.960  77.065  1.00 31.51  ? 85  VAL F N   1 
ATOM   16446 C CA  . VAL F 1 85  ? -3.701  14.333  77.561  1.00 34.41  ? 85  VAL F CA  1 
ATOM   16447 C C   . VAL F 1 85  ? -5.049  14.742  78.151  1.00 36.86  ? 85  VAL F C   1 
ATOM   16448 O O   . VAL F 1 85  ? -5.125  15.263  79.271  1.00 37.89  ? 85  VAL F O   1 
ATOM   16449 C CB  . VAL F 1 85  ? -3.256  15.289  76.441  1.00 36.40  ? 85  VAL F CB  1 
ATOM   16450 C CG1 . VAL F 1 85  ? -3.371  16.729  76.905  1.00 35.56  ? 85  VAL F CG1 1 
ATOM   16451 C CG2 . VAL F 1 85  ? -1.835  14.978  76.042  1.00 29.46  ? 85  VAL F CG2 1 
ATOM   16452 N N   . LEU F 1 86  ? -6.137  14.467  77.428  1.00 32.39  ? 86  LEU F N   1 
ATOM   16453 C CA  . LEU F 1 86  ? -7.457  14.828  77.930  1.00 34.23  ? 86  LEU F CA  1 
ATOM   16454 C C   . LEU F 1 86  ? -7.812  14.102  79.222  1.00 32.21  ? 86  LEU F C   1 
ATOM   16455 O O   . LEU F 1 86  ? -8.658  14.593  79.978  1.00 24.49  ? 86  LEU F O   1 
ATOM   16456 C CB  . LEU F 1 86  ? -8.521  14.548  76.869  1.00 31.22  ? 86  LEU F CB  1 
ATOM   16457 C CG  . LEU F 1 86  ? -8.608  15.562  75.737  1.00 34.51  ? 86  LEU F CG  1 
ATOM   16458 C CD1 . LEU F 1 86  ? -9.900  15.324  74.931  1.00 27.82  ? 86  LEU F CD1 1 
ATOM   16459 C CD2 . LEU F 1 86  ? -8.549  16.975  76.298  1.00 30.31  ? 86  LEU F CD2 1 
ATOM   16460 N N   . GLN F 1 87  ? -7.205  12.944  79.481  1.00 32.20  ? 87  GLN F N   1 
ATOM   16461 C CA  . GLN F 1 87  ? -7.421  12.227  80.733  1.00 39.31  ? 87  GLN F CA  1 
ATOM   16462 C C   . GLN F 1 87  ? -6.387  12.559  81.806  1.00 40.86  ? 87  GLN F C   1 
ATOM   16463 O O   . GLN F 1 87  ? -6.652  12.316  82.988  1.00 41.14  ? 87  GLN F O   1 
ATOM   16464 C CB  . GLN F 1 87  ? -7.408  10.716  80.484  1.00 39.31  ? 87  GLN F CB  1 
ATOM   16465 C CG  . GLN F 1 87  ? -8.225  10.307  79.266  1.00 44.45  ? 87  GLN F CG  1 
ATOM   16466 C CD  . GLN F 1 87  ? -8.830  8.931   79.358  1.00 43.69  ? 87  GLN F CD  1 
ATOM   16467 O OE1 . GLN F 1 87  ? -9.680  8.667   80.207  1.00 51.62  ? 87  GLN F OE1 1 
ATOM   16468 N NE2 . GLN F 1 87  ? -8.391  8.037   78.474  1.00 38.74  ? 87  GLN F NE2 1 
ATOM   16469 N N   . ASP F 1 88  ? -5.227  13.096  81.425  1.00 40.85  ? 88  ASP F N   1 
ATOM   16470 C CA  . ASP F 1 88  ? -4.166  13.435  82.372  1.00 41.91  ? 88  ASP F CA  1 
ATOM   16471 C C   . ASP F 1 88  ? -4.688  14.361  83.469  1.00 41.84  ? 88  ASP F C   1 
ATOM   16472 O O   . ASP F 1 88  ? -5.126  15.481  83.165  1.00 43.49  ? 88  ASP F O   1 
ATOM   16473 C CB  . ASP F 1 88  ? -3.004  14.098  81.634  1.00 43.66  ? 88  ASP F CB  1 
ATOM   16474 C CG  . ASP F 1 88  ? -1.718  14.128  82.460  1.00 45.60  ? 88  ASP F CG  1 
ATOM   16475 O OD1 . ASP F 1 88  ? -1.811  14.213  83.698  1.00 46.50  ? 88  ASP F OD1 1 
ATOM   16476 O OD2 . ASP F 1 88  ? -0.616  14.084  81.867  1.00 44.39  ? 88  ASP F OD2 1 
ATOM   16477 N N   . PRO F 1 89  ? -4.652  13.949  84.743  1.00 45.42  ? 89  PRO F N   1 
ATOM   16478 C CA  . PRO F 1 89  ? -5.199  14.808  85.810  1.00 44.85  ? 89  PRO F CA  1 
ATOM   16479 C C   . PRO F 1 89  ? -4.461  16.131  85.974  1.00 39.12  ? 89  PRO F C   1 
ATOM   16480 O O   . PRO F 1 89  ? -5.062  17.098  86.449  1.00 37.53  ? 89  PRO F O   1 
ATOM   16481 C CB  . PRO F 1 89  ? -5.072  13.935  87.070  1.00 44.56  ? 89  PRO F CB  1 
ATOM   16482 C CG  . PRO F 1 89  ? -4.876  12.507  86.542  1.00 46.27  ? 89  PRO F CG  1 
ATOM   16483 C CD  . PRO F 1 89  ? -4.117  12.678  85.270  1.00 44.76  ? 89  PRO F CD  1 
ATOM   16484 N N   . GLU F 1 90  ? -3.191  16.218  85.588  1.00 43.63  ? 90  GLU F N   1 
ATOM   16485 C CA  . GLU F 1 90  ? -2.517  17.511  85.624  1.00 47.14  ? 90  GLU F CA  1 
ATOM   16486 C C   . GLU F 1 90  ? -3.110  18.468  84.589  1.00 46.12  ? 90  GLU F C   1 
ATOM   16487 O O   . GLU F 1 90  ? -3.260  19.667  84.856  1.00 38.72  ? 90  GLU F O   1 
ATOM   16488 C CB  . GLU F 1 90  ? -1.016  17.317  85.407  1.00 48.76  ? 90  GLU F CB  1 
ATOM   16489 C CG  . GLU F 1 90  ? -0.186  17.571  86.666  1.00 56.64  ? 90  GLU F CG  1 
ATOM   16490 C CD  . GLU F 1 90  ? 1.223   17.009  86.578  1.00 68.01  ? 90  GLU F CD  1 
ATOM   16491 O OE1 . GLU F 1 90  ? 1.348   15.792  86.331  1.00 67.23  ? 90  GLU F OE1 1 
ATOM   16492 O OE2 . GLU F 1 90  ? 2.202   17.778  86.751  1.00 64.12  ? 90  GLU F OE2 1 
ATOM   16493 N N   . PHE F 1 91  ? -3.468  17.949  83.405  1.00 46.99  ? 91  PHE F N   1 
ATOM   16494 C CA  . PHE F 1 91  ? -4.162  18.759  82.401  1.00 40.15  ? 91  PHE F CA  1 
ATOM   16495 C C   . PHE F 1 91  ? -5.540  19.181  82.890  1.00 34.33  ? 91  PHE F C   1 
ATOM   16496 O O   . PHE F 1 91  ? -5.958  20.325  82.680  1.00 40.09  ? 91  PHE F O   1 
ATOM   16497 C CB  . PHE F 1 91  ? -4.282  17.979  81.085  1.00 38.75  ? 91  PHE F CB  1 
ATOM   16498 C CG  . PHE F 1 91  ? -5.072  18.700  80.025  1.00 40.14  ? 91  PHE F CG  1 
ATOM   16499 C CD1 . PHE F 1 91  ? -4.541  19.803  79.371  1.00 35.51  ? 91  PHE F CD1 1 
ATOM   16500 C CD2 . PHE F 1 91  ? -6.360  18.294  79.702  1.00 38.37  ? 91  PHE F CD2 1 
ATOM   16501 C CE1 . PHE F 1 91  ? -5.270  20.476  78.411  1.00 38.79  ? 91  PHE F CE1 1 
ATOM   16502 C CE2 . PHE F 1 91  ? -7.094  18.965  78.739  1.00 37.10  ? 91  PHE F CE2 1 
ATOM   16503 C CZ  . PHE F 1 91  ? -6.550  20.058  78.095  1.00 36.42  ? 91  PHE F CZ  1 
ATOM   16504 N N   . ILE F 1 92  ? -6.264  18.266  83.538  1.00 33.01  ? 92  ILE F N   1 
ATOM   16505 C CA  . ILE F 1 92  ? -7.584  18.588  84.066  1.00 32.97  ? 92  ILE F CA  1 
ATOM   16506 C C   . ILE F 1 92  ? -7.492  19.707  85.086  1.00 33.87  ? 92  ILE F C   1 
ATOM   16507 O O   . ILE F 1 92  ? -8.336  20.611  85.113  1.00 32.74  ? 92  ILE F O   1 
ATOM   16508 C CB  . ILE F 1 92  ? -8.241  17.342  84.684  1.00 38.84  ? 92  ILE F CB  1 
ATOM   16509 C CG1 . ILE F 1 92  ? -8.512  16.284  83.620  1.00 42.56  ? 92  ILE F CG1 1 
ATOM   16510 C CG2 . ILE F 1 92  ? -9.526  17.727  85.414  1.00 36.58  ? 92  ILE F CG2 1 
ATOM   16511 C CD1 . ILE F 1 92  ? -9.199  15.077  84.175  1.00 32.60  ? 92  ILE F CD1 1 
ATOM   16512 N N   . ASP F 1 93  ? -6.469  19.674  85.940  1.00 34.41  ? 93  ASP F N   1 
ATOM   16513 C CA  . ASP F 1 93  ? -6.419  20.653  87.019  1.00 39.73  ? 93  ASP F CA  1 
ATOM   16514 C C   . ASP F 1 93  ? -6.181  22.047  86.471  1.00 35.61  ? 93  ASP F C   1 
ATOM   16515 O O   . ASP F 1 93  ? -6.770  23.012  86.966  1.00 36.23  ? 93  ASP F O   1 
ATOM   16516 C CB  . ASP F 1 93  ? -5.358  20.275  88.050  1.00 39.35  ? 93  ASP F CB  1 
ATOM   16517 C CG  . ASP F 1 93  ? -5.957  19.569  89.269  1.00 46.22  ? 93  ASP F CG  1 
ATOM   16518 O OD1 . ASP F 1 93  ? -6.946  18.814  89.112  1.00 40.42  ? 93  ASP F OD1 1 
ATOM   16519 O OD2 . ASP F 1 93  ? -5.454  19.783  90.393  1.00 57.51  ? 93  ASP F OD2 1 
ATOM   16520 N N   . ARG F 1 94  ? -5.376  22.162  85.406  1.00 37.32  ? 94  ARG F N   1 
ATOM   16521 C CA  . ARG F 1 94  ? -5.126  23.469  84.800  1.00 32.45  ? 94  ARG F CA  1 
ATOM   16522 C C   . ARG F 1 94  ? -6.386  24.061  84.184  1.00 37.26  ? 94  ARG F C   1 
ATOM   16523 O O   . ARG F 1 94  ? -6.543  25.288  84.163  1.00 37.89  ? 94  ARG F O   1 
ATOM   16524 C CB  . ARG F 1 94  ? -4.035  23.362  83.743  1.00 38.40  ? 94  ARG F CB  1 
ATOM   16525 C CG  . ARG F 1 94  ? -2.782  22.637  84.210  1.00 40.66  ? 94  ARG F CG  1 
ATOM   16526 C CD  . ARG F 1 94  ? -1.566  23.240  83.564  1.00 38.28  ? 94  ARG F CD  1 
ATOM   16527 N NE  . ARG F 1 94  ? -0.677  22.239  82.986  1.00 47.11  ? 94  ARG F NE  1 
ATOM   16528 C CZ  . ARG F 1 94  ? 0.461   21.825  83.532  1.00 56.40  ? 94  ARG F CZ  1 
ATOM   16529 N NH1 . ARG F 1 94  ? 0.872   22.275  84.712  1.00 52.59  ? 94  ARG F NH1 1 
ATOM   16530 N NH2 . ARG F 1 94  ? 1.220   20.952  82.869  1.00 48.35  ? 94  ARG F NH2 1 
ATOM   16531 N N   . LEU F 1 95  ? -7.284  23.217  83.658  1.00 33.58  ? 95  LEU F N   1 
ATOM   16532 C CA  . LEU F 1 95  ? -8.589  23.714  83.237  1.00 35.95  ? 95  LEU F CA  1 
ATOM   16533 C C   . LEU F 1 95  ? -9.493  23.980  84.432  1.00 35.71  ? 95  LEU F C   1 
ATOM   16534 O O   . LEU F 1 95  ? -10.352 24.865  84.370  1.00 35.51  ? 95  LEU F O   1 
ATOM   16535 C CB  . LEU F 1 95  ? -9.286  22.730  82.281  1.00 30.34  ? 95  LEU F CB  1 
ATOM   16536 C CG  . LEU F 1 95  ? -8.566  22.361  80.986  1.00 30.78  ? 95  LEU F CG  1 
ATOM   16537 C CD1 . LEU F 1 95  ? -9.366  21.337  80.255  1.00 32.05  ? 95  LEU F CD1 1 
ATOM   16538 C CD2 . LEU F 1 95  ? -8.353  23.573  80.136  1.00 30.62  ? 95  LEU F CD2 1 
ATOM   16539 N N   . ALA F 1 96  ? -9.335  23.220  85.514  1.00 36.07  ? 96  ALA F N   1 
ATOM   16540 C CA  . ALA F 1 96  ? -10.157 23.465  86.692  1.00 40.58  ? 96  ALA F CA  1 
ATOM   16541 C C   . ALA F 1 96  ? -9.854  24.830  87.287  1.00 38.32  ? 96  ALA F C   1 
ATOM   16542 O O   . ALA F 1 96  ? -10.727 25.447  87.908  1.00 39.03  ? 96  ALA F O   1 
ATOM   16543 C CB  . ALA F 1 96  ? -9.943  22.362  87.731  1.00 39.45  ? 96  ALA F CB  1 
ATOM   16544 N N   . ALA F 1 97  ? -8.630  25.321  87.085  1.00 37.72  ? 97  ALA F N   1 
ATOM   16545 C CA  . ALA F 1 97  ? -8.284  26.670  87.510  1.00 44.04  ? 97  ALA F CA  1 
ATOM   16546 C C   . ALA F 1 97  ? -9.263  27.687  86.934  1.00 46.72  ? 97  ALA F C   1 
ATOM   16547 O O   . ALA F 1 97  ? -9.756  28.569  87.649  1.00 40.35  ? 97  ALA F O   1 
ATOM   16548 C CB  . ALA F 1 97  ? -6.850  27.000  87.089  1.00 39.34  ? 97  ALA F CB  1 
ATOM   16549 N N   . HIS F 1 98  ? -9.575  27.563  85.641  1.00 38.52  ? 98  HIS F N   1 
ATOM   16550 C CA  . HIS F 1 98  ? -10.457 28.532  85.005  1.00 41.12  ? 98  HIS F CA  1 
ATOM   16551 C C   . HIS F 1 98  ? -11.917 28.227  85.306  1.00 41.86  ? 98  HIS F C   1 
ATOM   16552 O O   . HIS F 1 98  ? -12.676 29.103  85.734  1.00 43.47  ? 98  HIS F O   1 
ATOM   16553 C CB  . HIS F 1 98  ? -10.220 28.543  83.495  1.00 41.75  ? 98  HIS F CB  1 
ATOM   16554 C CG  . HIS F 1 98  ? -8.848  28.983  83.107  1.00 42.97  ? 98  HIS F CG  1 
ATOM   16555 N ND1 . HIS F 1 98  ? -8.517  30.307  82.918  1.00 45.27  ? 98  HIS F ND1 1 
ATOM   16556 C CD2 . HIS F 1 98  ? -7.718  28.273  82.880  1.00 39.60  ? 98  HIS F CD2 1 
ATOM   16557 C CE1 . HIS F 1 98  ? -7.240  30.394  82.594  1.00 46.43  ? 98  HIS F CE1 1 
ATOM   16558 N NE2 . HIS F 1 98  ? -6.734  29.174  82.560  1.00 41.99  ? 98  HIS F NE2 1 
ATOM   16559 N N   . THR F 1 99  ? -12.336 26.987  85.075  1.00 40.80  ? 99  THR F N   1 
ATOM   16560 C CA  . THR F 1 99  ? -13.759 26.692  85.152  1.00 39.16  ? 99  THR F CA  1 
ATOM   16561 C C   . THR F 1 99  ? -14.252 26.694  86.589  1.00 40.38  ? 99  THR F C   1 
ATOM   16562 O O   . THR F 1 99  ? -15.441 26.934  86.833  1.00 36.97  ? 99  THR F O   1 
ATOM   16563 C CB  . THR F 1 99  ? -14.037 25.353  84.483  1.00 41.58  ? 99  THR F CB  1 
ATOM   16564 O OG1 . THR F 1 99  ? -13.297 24.325  85.159  1.00 38.45  ? 99  THR F OG1 1 
ATOM   16565 C CG2 . THR F 1 99  ? -13.608 25.416  83.022  1.00 40.44  ? 99  THR F CG2 1 
ATOM   16566 N N   . GLY F 1 100 ? -13.355 26.441  87.541  1.00 40.64  ? 100 GLY F N   1 
ATOM   16567 C CA  . GLY F 1 100 ? -13.692 26.415  88.949  1.00 44.82  ? 100 GLY F CA  1 
ATOM   16568 C C   . GLY F 1 100 ? -14.793 25.429  89.277  1.00 45.79  ? 100 GLY F C   1 
ATOM   16569 O O   . GLY F 1 100 ? -14.573 24.216  89.277  1.00 48.33  ? 100 GLY F O   1 
ATOM   16570 N N   . THR F 1 101 ? -15.989 25.947  89.555  1.00 42.46  ? 101 THR F N   1 
ATOM   16571 C CA  . THR F 1 101 ? -17.135 25.109  89.871  1.00 43.36  ? 101 THR F CA  1 
ATOM   16572 C C   . THR F 1 101 ? -17.694 24.383  88.644  1.00 46.51  ? 101 THR F C   1 
ATOM   16573 O O   . THR F 1 101 ? -18.456 23.423  88.795  1.00 41.81  ? 101 THR F O   1 
ATOM   16574 C CB  . THR F 1 101 ? -18.221 25.982  90.498  1.00 43.81  ? 101 THR F CB  1 
ATOM   16575 O OG1 . THR F 1 101 ? -19.426 25.867  89.734  1.00 43.08  ? 101 THR F OG1 1 
ATOM   16576 C CG2 . THR F 1 101 ? -17.776 27.459  90.489  1.00 43.80  ? 101 THR F CG2 1 
ATOM   16577 N N   . GLY F 1 102 ? -17.335 24.815  87.434  1.00 45.91  ? 102 GLY F N   1 
ATOM   16578 C CA  . GLY F 1 102 ? -17.985 24.353  86.229  1.00 44.39  ? 102 GLY F CA  1 
ATOM   16579 C C   . GLY F 1 102 ? -19.179 25.184  85.788  1.00 45.16  ? 102 GLY F C   1 
ATOM   16580 O O   . GLY F 1 102 ? -19.495 25.198  84.592  1.00 43.87  ? 102 GLY F O   1 
ATOM   16581 N N   . ALA F 1 103 ? -19.831 25.898  86.711  1.00 40.38  ? 103 ALA F N   1 
ATOM   16582 C CA  . ALA F 1 103 ? -21.033 26.655  86.374  1.00 45.46  ? 103 ALA F CA  1 
ATOM   16583 C C   . ALA F 1 103 ? -20.736 27.705  85.309  1.00 41.00  ? 103 ALA F C   1 
ATOM   16584 O O   . ALA F 1 103 ? -19.726 28.409  85.374  1.00 37.48  ? 103 ALA F O   1 
ATOM   16585 C CB  . ALA F 1 103 ? -21.617 27.319  87.628  1.00 41.23  ? 103 ALA F CB  1 
ATOM   16586 N N   . GLY F 1 104 ? -21.617 27.789  84.315  1.00 42.67  ? 104 GLY F N   1 
ATOM   16587 C CA  . GLY F 1 104 ? -21.471 28.738  83.236  1.00 41.69  ? 104 GLY F CA  1 
ATOM   16588 C C   . GLY F 1 104 ? -20.451 28.374  82.178  1.00 40.45  ? 104 GLY F C   1 
ATOM   16589 O O   . GLY F 1 104 ? -20.281 29.141  81.227  1.00 42.71  ? 104 GLY F O   1 
ATOM   16590 N N   . TRP F 1 105 ? -19.771 27.241  82.301  1.00 38.03  ? 105 TRP F N   1 
ATOM   16591 C CA  . TRP F 1 105 ? -18.752 26.834  81.343  1.00 39.11  ? 105 TRP F CA  1 
ATOM   16592 C C   . TRP F 1 105 ? -19.232 25.678  80.470  1.00 35.48  ? 105 TRP F C   1 
ATOM   16593 O O   . TRP F 1 105 ? -20.095 24.894  80.867  1.00 34.38  ? 105 TRP F O   1 
ATOM   16594 C CB  . TRP F 1 105 ? -17.473 26.416  82.057  1.00 35.28  ? 105 TRP F CB  1 
ATOM   16595 C CG  . TRP F 1 105 ? -16.672 27.555  82.538  1.00 40.00  ? 105 TRP F CG  1 
ATOM   16596 C CD1 . TRP F 1 105 ? -16.847 28.248  83.701  1.00 39.36  ? 105 TRP F CD1 1 
ATOM   16597 C CD2 . TRP F 1 105 ? -15.556 28.159  81.873  1.00 39.63  ? 105 TRP F CD2 1 
ATOM   16598 N NE1 . TRP F 1 105 ? -15.903 29.242  83.803  1.00 39.50  ? 105 TRP F NE1 1 
ATOM   16599 C CE2 . TRP F 1 105 ? -15.100 29.210  82.694  1.00 38.74  ? 105 TRP F CE2 1 
ATOM   16600 C CE3 . TRP F 1 105 ? -14.906 27.919  80.663  1.00 37.26  ? 105 TRP F CE3 1 
ATOM   16601 C CZ2 . TRP F 1 105 ? -14.024 30.013  82.344  1.00 38.77  ? 105 TRP F CZ2 1 
ATOM   16602 C CZ3 . TRP F 1 105 ? -13.829 28.709  80.321  1.00 35.50  ? 105 TRP F CZ3 1 
ATOM   16603 C CH2 . TRP F 1 105 ? -13.399 29.746  81.157  1.00 38.31  ? 105 TRP F CH2 1 
ATOM   16604 N N   . SER F 1 106 ? -18.648 25.565  79.278  1.00 32.81  ? 106 SER F N   1 
ATOM   16605 C CA  . SER F 1 106 ? -18.918 24.430  78.408  1.00 33.55  ? 106 SER F CA  1 
ATOM   16606 C C   . SER F 1 106 ? -17.654 24.051  77.647  1.00 35.72  ? 106 SER F C   1 
ATOM   16607 O O   . SER F 1 106 ? -16.741 24.860  77.476  1.00 33.06  ? 106 SER F O   1 
ATOM   16608 C CB  . SER F 1 106 ? -20.046 24.729  77.414  1.00 32.28  ? 106 SER F CB  1 
ATOM   16609 O OG  . SER F 1 106 ? -19.583 25.628  76.428  1.00 32.00  ? 106 SER F OG  1 
ATOM   16610 N N   . LEU F 1 107 ? -17.609 22.794  77.204  1.00 29.95  ? 107 LEU F N   1 
ATOM   16611 C CA  . LEU F 1 107 ? -16.539 22.302  76.358  1.00 29.79  ? 107 LEU F CA  1 
ATOM   16612 C C   . LEU F 1 107 ? -16.917 22.518  74.896  1.00 30.53  ? 107 LEU F C   1 
ATOM   16613 O O   . LEU F 1 107 ? -18.064 22.290  74.506  1.00 32.36  ? 107 LEU F O   1 
ATOM   16614 C CB  . LEU F 1 107 ? -16.275 20.822  76.638  1.00 29.05  ? 107 LEU F CB  1 
ATOM   16615 C CG  . LEU F 1 107 ? -15.000 20.251  76.035  1.00 26.38  ? 107 LEU F CG  1 
ATOM   16616 C CD1 . LEU F 1 107 ? -13.843 21.170  76.249  1.00 32.17  ? 107 LEU F CD1 1 
ATOM   16617 C CD2 . LEU F 1 107 ? -14.692 18.910  76.621  1.00 30.67  ? 107 LEU F CD2 1 
ATOM   16618 N N   . PHE F 1 108 ? -15.950 22.997  74.095  1.00 28.61  ? 108 PHE F N   1 
ATOM   16619 C CA  . PHE F 1 108 ? -16.124 23.244  72.664  1.00 23.83  ? 108 PHE F CA  1 
ATOM   16620 C C   . PHE F 1 108 ? -15.081 22.408  71.939  1.00 27.35  ? 108 PHE F C   1 
ATOM   16621 O O   . PHE F 1 108 ? -14.046 22.935  71.503  1.00 26.58  ? 108 PHE F O   1 
ATOM   16622 C CB  . PHE F 1 108 ? -15.974 24.723  72.309  1.00 26.30  ? 108 PHE F CB  1 
ATOM   16623 C CG  . PHE F 1 108 ? -16.491 25.080  70.935  1.00 23.64  ? 108 PHE F CG  1 
ATOM   16624 C CD1 . PHE F 1 108 ? -17.828 24.901  70.611  1.00 23.80  ? 108 PHE F CD1 1 
ATOM   16625 C CD2 . PHE F 1 108 ? -15.628 25.591  69.963  1.00 24.33  ? 108 PHE F CD2 1 
ATOM   16626 C CE1 . PHE F 1 108 ? -18.310 25.238  69.341  1.00 26.97  ? 108 PHE F CE1 1 
ATOM   16627 C CE2 . PHE F 1 108 ? -16.089 25.917  68.691  1.00 25.84  ? 108 PHE F CE2 1 
ATOM   16628 C CZ  . PHE F 1 108 ? -17.437 25.746  68.377  1.00 26.84  ? 108 PHE F CZ  1 
ATOM   16629 N N   . PRO F 1 109 ? -15.303 21.100  71.813  1.00 30.85  ? 109 PRO F N   1 
ATOM   16630 C CA  . PRO F 1 109 ? -14.271 20.227  71.256  1.00 26.45  ? 109 PRO F CA  1 
ATOM   16631 C C   . PRO F 1 109 ? -14.429 20.074  69.761  1.00 25.01  ? 109 PRO F C   1 
ATOM   16632 O O   . PRO F 1 109 ? -15.529 20.134  69.215  1.00 27.49  ? 109 PRO F O   1 
ATOM   16633 C CB  . PRO F 1 109 ? -14.530 18.892  71.970  1.00 33.21  ? 109 PRO F CB  1 
ATOM   16634 C CG  . PRO F 1 109 ? -16.007 18.895  72.209  1.00 26.66  ? 109 PRO F CG  1 
ATOM   16635 C CD  . PRO F 1 109 ? -16.446 20.332  72.345  1.00 24.13  ? 109 PRO F CD  1 
ATOM   16636 N N   . CYS F 1 110 ? -13.290 19.870  69.103  1.00 26.43  ? 110 CYS F N   1 
ATOM   16637 C CA  . CYS F 1 110 ? -13.297 19.556  67.681  1.00 26.29  ? 110 CYS F CA  1 
ATOM   16638 C C   . CYS F 1 110 ? -13.860 18.163  67.427  1.00 28.39  ? 110 CYS F C   1 
ATOM   16639 O O   . CYS F 1 110 ? -14.748 17.984  66.583  1.00 29.60  ? 110 CYS F O   1 
ATOM   16640 C CB  . CYS F 1 110 ? -11.885 19.661  67.120  1.00 30.99  ? 110 CYS F CB  1 
ATOM   16641 S SG  . CYS F 1 110 ? -11.730 19.061  65.423  1.00 27.64  ? 110 CYS F SG  1 
ATOM   16642 N N   . VAL F 1 111 ? -13.347 17.162  68.131  1.00 24.46  ? 111 VAL F N   1 
ATOM   16643 C CA  . VAL F 1 111 ? -13.837 15.794  68.009  1.00 28.98  ? 111 VAL F CA  1 
ATOM   16644 C C   . VAL F 1 111 ? -14.453 15.421  69.341  1.00 27.30  ? 111 VAL F C   1 
ATOM   16645 O O   . VAL F 1 111 ? -13.778 15.486  70.374  1.00 29.40  ? 111 VAL F O   1 
ATOM   16646 C CB  . VAL F 1 111 ? -12.725 14.803  67.629  1.00 26.08  ? 111 VAL F CB  1 
ATOM   16647 C CG1 . VAL F 1 111 ? -13.327 13.535  67.057  1.00 21.30  ? 111 VAL F CG1 1 
ATOM   16648 C CG2 . VAL F 1 111 ? -11.738 15.437  66.615  1.00 29.99  ? 111 VAL F CG2 1 
ATOM   16649 N N   . SER F 1 112 ? -15.724 15.017  69.321  1.00 22.94  ? 112 SER F N   1 
ATOM   16650 C CA  . SER F 1 112 ? -16.432 14.627  70.543  1.00 29.66  ? 112 SER F CA  1 
ATOM   16651 C C   . SER F 1 112 ? -16.066 13.180  70.906  1.00 31.01  ? 112 SER F C   1 
ATOM   16652 O O   . SER F 1 112 ? -16.853 12.239  70.771  1.00 29.01  ? 112 SER F O   1 
ATOM   16653 C CB  . SER F 1 112 ? -17.937 14.799  70.369  1.00 30.46  ? 112 SER F CB  1 
ATOM   16654 O OG  . SER F 1 112 ? -18.309 16.155  70.508  1.00 34.55  ? 112 SER F OG  1 
ATOM   16655 N N   . THR F 1 113 ? -14.853 13.010  71.411  1.00 27.32  ? 113 THR F N   1 
ATOM   16656 C CA  . THR F 1 113 ? -14.326 11.695  71.729  1.00 29.58  ? 113 THR F CA  1 
ATOM   16657 C C   . THR F 1 113 ? -14.788 11.266  73.113  1.00 27.34  ? 113 THR F C   1 
ATOM   16658 O O   . THR F 1 113 ? -15.412 12.029  73.840  1.00 28.10  ? 113 THR F O   1 
ATOM   16659 C CB  . THR F 1 113 ? -12.810 11.707  71.703  1.00 29.88  ? 113 THR F CB  1 
ATOM   16660 O OG1 . THR F 1 113 ? -12.356 12.582  72.748  1.00 31.65  ? 113 THR F OG1 1 
ATOM   16661 C CG2 . THR F 1 113 ? -12.291 12.171  70.352  1.00 27.71  ? 113 THR F CG2 1 
ATOM   16662 N N   . ARG F 1 114 ? -14.463 10.020  73.471  1.00 27.10  ? 114 ARG F N   1 
ATOM   16663 C CA  . ARG F 1 114 ? -14.766 9.512   74.806  1.00 30.25  ? 114 ARG F CA  1 
ATOM   16664 C C   . ARG F 1 114 ? -14.179 10.409  75.887  1.00 33.72  ? 114 ARG F C   1 
ATOM   16665 O O   . ARG F 1 114 ? -14.888 10.854  76.801  1.00 31.18  ? 114 ARG F O   1 
ATOM   16666 C CB  . ARG F 1 114 ? -14.213 8.097   74.960  1.00 32.81  ? 114 ARG F CB  1 
ATOM   16667 C CG  . ARG F 1 114 ? -14.495 7.451   76.313  1.00 31.88  ? 114 ARG F CG  1 
ATOM   16668 C CD  . ARG F 1 114 ? -14.019 6.011   76.305  1.00 28.52  ? 114 ARG F CD  1 
ATOM   16669 N NE  . ARG F 1 114 ? -13.981 5.418   77.636  1.00 29.66  ? 114 ARG F NE  1 
ATOM   16670 C CZ  . ARG F 1 114 ? -15.053 5.068   78.323  1.00 30.13  ? 114 ARG F CZ  1 
ATOM   16671 N NH1 . ARG F 1 114 ? -16.273 5.290   77.856  1.00 30.25  ? 114 ARG F NH1 1 
ATOM   16672 N NH2 . ARG F 1 114 ? -14.900 4.476   79.501  1.00 28.98  ? 114 ARG F NH2 1 
ATOM   16673 N N   . ALA F 1 115 ? -12.867 10.661  75.805  1.00 32.95  ? 115 ALA F N   1 
ATOM   16674 C CA  . ALA F 1 115 ? -12.184 11.439  76.836  1.00 34.07  ? 115 ALA F CA  1 
ATOM   16675 C C   . ALA F 1 115 ? -12.800 12.821  76.971  1.00 31.57  ? 115 ALA F C   1 
ATOM   16676 O O   . ALA F 1 115 ? -13.140 13.257  78.080  1.00 32.00  ? 115 ALA F O   1 
ATOM   16677 C CB  . ALA F 1 115 ? -10.695 11.535  76.513  1.00 35.59  ? 115 ALA F CB  1 
ATOM   16678 N N   . ALA F 1 116 ? -12.984 13.508  75.838  1.00 32.88  ? 116 ALA F N   1 
ATOM   16679 C CA  . ALA F 1 116 ? -13.721 14.769  75.809  1.00 31.07  ? 116 ALA F CA  1 
ATOM   16680 C C   . ALA F 1 116 ? -14.982 14.684  76.641  1.00 28.92  ? 116 ALA F C   1 
ATOM   16681 O O   . ALA F 1 116 ? -15.185 15.475  77.563  1.00 30.58  ? 116 ALA F O   1 
ATOM   16682 C CB  . ALA F 1 116 ? -14.074 15.143  74.369  1.00 27.87  ? 116 ALA F CB  1 
ATOM   16683 N N   . ALA F 1 117 ? -15.837 13.711  76.334  1.00 28.55  ? 117 ALA F N   1 
ATOM   16684 C CA  . ALA F 1 117 ? -17.071 13.551  77.091  1.00 30.89  ? 117 ALA F CA  1 
ATOM   16685 C C   . ALA F 1 117 ? -16.779 13.403  78.578  1.00 30.03  ? 117 ALA F C   1 
ATOM   16686 O O   . ALA F 1 117 ? -17.399 14.072  79.414  1.00 30.58  ? 117 ALA F O   1 
ATOM   16687 C CB  . ALA F 1 117 ? -17.841 12.340  76.566  1.00 31.97  ? 117 ALA F CB  1 
ATOM   16688 N N   . GLN F 1 118 ? -15.840 12.516  78.921  1.00 28.46  ? 118 GLN F N   1 
ATOM   16689 C CA  . GLN F 1 118 ? -15.399 12.359  80.303  1.00 29.31  ? 118 GLN F CA  1 
ATOM   16690 C C   . GLN F 1 118 ? -14.889 13.674  80.881  1.00 31.52  ? 118 GLN F C   1 
ATOM   16691 O O   . GLN F 1 118 ? -15.116 13.973  82.060  1.00 32.87  ? 118 GLN F O   1 
ATOM   16692 C CB  . GLN F 1 118 ? -14.293 11.305  80.384  1.00 29.51  ? 118 GLN F CB  1 
ATOM   16693 C CG  . GLN F 1 118 ? -14.756 9.859   80.399  1.00 30.31  ? 118 GLN F CG  1 
ATOM   16694 C CD  . GLN F 1 118 ? -13.617 8.899   80.084  1.00 29.88  ? 118 GLN F CD  1 
ATOM   16695 O OE1 . GLN F 1 118 ? -12.622 9.278   79.462  1.00 34.97  ? 118 GLN F OE1 1 
ATOM   16696 N NE2 . GLN F 1 118 ? -13.747 7.656   80.524  1.00 32.14  ? 118 GLN F NE2 1 
ATOM   16697 N N   . LEU F 1 119 ? -14.168 14.458  80.079  1.00 32.00  ? 119 LEU F N   1 
ATOM   16698 C CA  . LEU F 1 119 ? -13.677 15.736  80.577  1.00 34.61  ? 119 LEU F CA  1 
ATOM   16699 C C   . LEU F 1 119 ? -14.819 16.613  81.072  1.00 33.50  ? 119 LEU F C   1 
ATOM   16700 O O   . LEU F 1 119 ? -14.685 17.285  82.098  1.00 32.41  ? 119 LEU F O   1 
ATOM   16701 C CB  . LEU F 1 119 ? -12.881 16.465  79.503  1.00 32.88  ? 119 LEU F CB  1 
ATOM   16702 C CG  . LEU F 1 119 ? -12.206 17.755  79.978  1.00 31.97  ? 119 LEU F CG  1 
ATOM   16703 C CD1 . LEU F 1 119 ? -11.259 17.487  81.141  1.00 33.48  ? 119 LEU F CD1 1 
ATOM   16704 C CD2 . LEU F 1 119 ? -11.452 18.381  78.833  1.00 35.53  ? 119 LEU F CD2 1 
ATOM   16705 N N   . THR F 1 120 ? -15.948 16.622  80.357  1.00 28.23  ? 120 THR F N   1 
ATOM   16706 C CA  . THR F 1 120 ? -17.083 17.432  80.784  1.00 27.49  ? 120 THR F CA  1 
ATOM   16707 C C   . THR F 1 120 ? -17.591 16.988  82.142  1.00 36.32  ? 120 THR F C   1 
ATOM   16708 O O   . THR F 1 120 ? -18.112 17.804  82.910  1.00 30.24  ? 120 THR F O   1 
ATOM   16709 C CB  . THR F 1 120 ? -18.233 17.347  79.774  1.00 34.44  ? 120 THR F CB  1 
ATOM   16710 O OG1 . THR F 1 120 ? -18.766 16.009  79.754  1.00 30.61  ? 120 THR F OG1 1 
ATOM   16711 C CG2 . THR F 1 120 ? -17.769 17.755  78.365  1.00 32.71  ? 120 THR F CG2 1 
ATOM   16712 N N   . ARG F 1 121 ? -17.474 15.695  82.441  1.00 31.88  ? 121 ARG F N   1 
ATOM   16713 C CA  . ARG F 1 121 ? -17.962 15.200  83.718  1.00 36.30  ? 121 ARG F CA  1 
ATOM   16714 C C   . ARG F 1 121 ? -16.957 15.459  84.831  1.00 34.80  ? 121 ARG F C   1 
ATOM   16715 O O   . ARG F 1 121 ? -17.348 15.796  85.952  1.00 30.26  ? 121 ARG F O   1 
ATOM   16716 C CB  . ARG F 1 121 ? -18.286 13.713  83.605  1.00 33.33  ? 121 ARG F CB  1 
ATOM   16717 C CG  . ARG F 1 121 ? -19.084 13.167  84.775  1.00 46.47  ? 121 ARG F CG  1 
ATOM   16718 C CD  . ARG F 1 121 ? -20.547 13.643  84.775  1.00 46.17  ? 121 ARG F CD  1 
ATOM   16719 N NE  . ARG F 1 121 ? -21.477 12.754  84.077  1.00 60.58  ? 121 ARG F NE  1 
ATOM   16720 C CZ  . ARG F 1 121 ? -21.599 11.444  84.278  1.00 59.40  ? 121 ARG F CZ  1 
ATOM   16721 N NH1 . ARG F 1 121 ? -20.863 10.802  85.175  1.00 53.96  ? 121 ARG F NH1 1 
ATOM   16722 N NH2 . ARG F 1 121 ? -22.487 10.760  83.562  1.00 54.95  ? 121 ARG F NH2 1 
ATOM   16723 N N   . LYS F 1 122 ? -15.659 15.343  84.535  1.00 37.63  ? 122 LYS F N   1 
ATOM   16724 C CA  . LYS F 1 122 ? -14.649 15.521  85.576  1.00 35.55  ? 122 LYS F CA  1 
ATOM   16725 C C   . LYS F 1 122 ? -14.625 16.967  86.080  1.00 42.16  ? 122 LYS F C   1 
ATOM   16726 O O   . LYS F 1 122 ? -14.788 17.212  87.283  1.00 40.46  ? 122 LYS F O   1 
ATOM   16727 C CB  . LYS F 1 122 ? -13.294 15.052  85.055  1.00 29.22  ? 122 LYS F CB  1 
ATOM   16728 C CG  . LYS F 1 122 ? -13.076 13.576  85.320  1.00 36.87  ? 122 LYS F CG  1 
ATOM   16729 C CD  . LYS F 1 122 ? -11.753 13.047  84.781  1.00 36.30  ? 122 LYS F CD  1 
ATOM   16730 C CE  . LYS F 1 122 ? -11.890 11.629  84.187  1.00 35.73  ? 122 LYS F CE  1 
ATOM   16731 N NZ  . LYS F 1 122 ? -11.012 11.399  82.969  1.00 34.33  ? 122 LYS F NZ  1 
ATOM   16732 N N   . LEU F 1 123 ? -14.461 17.940  85.176  1.00 38.34  ? 123 LEU F N   1 
ATOM   16733 C CA  . LEU F 1 123 ? -14.960 19.288  85.436  1.00 36.58  ? 123 LEU F CA  1 
ATOM   16734 C C   . LEU F 1 123 ? -16.466 19.197  85.666  1.00 35.20  ? 123 LEU F C   1 
ATOM   16735 O O   . LEU F 1 123 ? -17.076 18.174  85.431  1.00 44.52  ? 123 LEU F O   1 
ATOM   16736 C CB  . LEU F 1 123 ? -14.640 20.212  84.254  1.00 35.06  ? 123 LEU F CB  1 
ATOM   16737 C CG  . LEU F 1 123 ? -13.162 20.257  83.845  1.00 37.63  ? 123 LEU F CG  1 
ATOM   16738 C CD1 . LEU F 1 123 ? -12.912 21.050  82.570  1.00 33.61  ? 123 LEU F CD1 1 
ATOM   16739 C CD2 . LEU F 1 123 ? -12.293 20.786  84.987  1.00 37.70  ? 123 LEU F CD2 1 
ATOM   16740 N N   . ASN F 1 124 ? -17.097 20.258  86.127  1.00 44.24  ? 124 ASN F N   1 
ATOM   16741 C CA  . ASN F 1 124 ? -18.553 20.188  86.257  1.00 44.44  ? 124 ASN F CA  1 
ATOM   16742 C C   . ASN F 1 124 ? -19.217 21.124  85.252  1.00 42.68  ? 124 ASN F C   1 
ATOM   16743 O O   . ASN F 1 124 ? -20.181 21.826  85.562  1.00 44.67  ? 124 ASN F O   1 
ATOM   16744 C CB  . ASN F 1 124 ? -19.002 20.487  87.688  1.00 47.79  ? 124 ASN F CB  1 
ATOM   16745 C CG  . ASN F 1 124 ? -20.354 19.847  88.039  1.00 44.11  ? 124 ASN F CG  1 
ATOM   16746 O OD1 . ASN F 1 124 ? -20.713 18.785  87.532  1.00 39.80  ? 124 ASN F OD1 1 
ATOM   16747 N ND2 . ASN F 1 124 ? -21.103 20.503  88.924  1.00 54.53  ? 124 ASN F ND2 1 
ATOM   16748 N N   . VAL F 1 125 ? -18.689 21.142  84.029  1.00 41.56  ? 125 VAL F N   1 
ATOM   16749 C CA  . VAL F 1 125 ? -19.189 22.012  82.972  1.00 34.14  ? 125 VAL F CA  1 
ATOM   16750 C C   . VAL F 1 125 ? -20.389 21.345  82.318  1.00 37.09  ? 125 VAL F C   1 
ATOM   16751 O O   . VAL F 1 125 ? -20.731 20.203  82.649  1.00 33.90  ? 125 VAL F O   1 
ATOM   16752 C CB  . VAL F 1 125 ? -18.089 22.309  81.936  1.00 38.36  ? 125 VAL F CB  1 
ATOM   16753 C CG1 . VAL F 1 125 ? -16.770 22.578  82.633  1.00 38.30  ? 125 VAL F CG1 1 
ATOM   16754 C CG2 . VAL F 1 125 ? -17.947 21.153  80.930  1.00 32.16  ? 125 VAL F CG2 1 
ATOM   16755 N N   . ALA F 1 126 ? -21.031 22.048  81.382  1.00 35.35  ? 126 ALA F N   1 
ATOM   16756 C CA  . ALA F 1 126 ? -22.176 21.494  80.667  1.00 34.75  ? 126 ALA F CA  1 
ATOM   16757 C C   . ALA F 1 126 ? -21.823 20.144  80.063  1.00 32.48  ? 126 ALA F C   1 
ATOM   16758 O O   . ALA F 1 126 ? -20.764 19.979  79.450  1.00 32.36  ? 126 ALA F O   1 
ATOM   16759 C CB  . ALA F 1 126 ? -22.635 22.461  79.569  1.00 37.03  ? 126 ALA F CB  1 
ATOM   16760 N N   . ALA F 1 127 ? -22.695 19.166  80.274  1.00 36.41  ? 127 ALA F N   1 
ATOM   16761 C CA  . ALA F 1 127 ? -22.465 17.842  79.716  1.00 32.84  ? 127 ALA F CA  1 
ATOM   16762 C C   . ALA F 1 127 ? -22.336 17.934  78.198  1.00 34.24  ? 127 ALA F C   1 
ATOM   16763 O O   . ALA F 1 127 ? -23.103 18.644  77.538  1.00 32.91  ? 127 ALA F O   1 
ATOM   16764 C CB  . ALA F 1 127 ? -23.608 16.903  80.106  1.00 37.11  ? 127 ALA F CB  1 
ATOM   16765 N N   . LEU F 1 128 ? -21.330 17.254  77.651  1.00 33.20  ? 128 LEU F N   1 
ATOM   16766 C CA  . LEU F 1 128 ? -21.194 17.161  76.207  1.00 30.66  ? 128 LEU F CA  1 
ATOM   16767 C C   . LEU F 1 128 ? -22.501 16.663  75.603  1.00 33.33  ? 128 LEU F C   1 
ATOM   16768 O O   . LEU F 1 128 ? -23.069 15.662  76.060  1.00 34.92  ? 128 LEU F O   1 
ATOM   16769 C CB  . LEU F 1 128 ? -20.049 16.216  75.843  1.00 31.35  ? 128 LEU F CB  1 
ATOM   16770 C CG  . LEU F 1 128 ? -19.186 16.506  74.606  1.00 30.11  ? 128 LEU F CG  1 
ATOM   16771 C CD1 . LEU F 1 128 ? -18.359 15.302  74.252  1.00 31.24  ? 128 LEU F CD1 1 
ATOM   16772 C CD2 . LEU F 1 128 ? -20.015 16.895  73.415  1.00 37.45  ? 128 LEU F CD2 1 
ATOM   16773 N N   . ASP F 1 129 ? -22.997 17.384  74.595  1.00 28.33  ? 129 ASP F N   1 
ATOM   16774 C CA  . ASP F 1 129 ? -24.175 16.926  73.873  1.00 28.32  ? 129 ASP F CA  1 
ATOM   16775 C C   . ASP F 1 129 ? -23.846 15.644  73.115  1.00 23.04  ? 129 ASP F C   1 
ATOM   16776 O O   . ASP F 1 129 ? -22.796 15.532  72.479  1.00 27.87  ? 129 ASP F O   1 
ATOM   16777 C CB  . ASP F 1 129 ? -24.670 18.017  72.917  1.00 29.86  ? 129 ASP F CB  1 
ATOM   16778 C CG  . ASP F 1 129 ? -26.125 17.833  72.522  1.00 31.60  ? 129 ASP F CG  1 
ATOM   16779 O OD1 . ASP F 1 129 ? -26.819 17.011  73.182  1.00 32.24  ? 129 ASP F OD1 1 
ATOM   16780 O OD2 . ASP F 1 129 ? -26.574 18.525  71.567  1.00 27.76  ? 129 ASP F OD2 1 
ATOM   16781 N N   . GLY F 1 130 ? -24.743 14.667  73.190  1.00 28.61  ? 130 GLY F N   1 
ATOM   16782 C CA  . GLY F 1 130 ? -24.440 13.349  72.660  1.00 20.21  ? 130 GLY F CA  1 
ATOM   16783 C C   . GLY F 1 130 ? -23.458 12.603  73.523  1.00 26.19  ? 130 GLY F C   1 
ATOM   16784 O O   . GLY F 1 130 ? -22.615 11.860  72.999  1.00 19.35  ? 130 GLY F O   1 
ATOM   16785 N N   . TYR F 1 131 ? -23.549 12.786  74.845  1.00 21.80  ? 131 TYR F N   1 
ATOM   16786 C CA  . TYR F 1 131 ? -22.566 12.223  75.775  1.00 26.26  ? 131 TYR F CA  1 
ATOM   16787 C C   . TYR F 1 131 ? -22.469 10.700  75.654  1.00 25.00  ? 131 TYR F C   1 
ATOM   16788 O O   . TYR F 1 131 ? -21.379 10.146  75.460  1.00 25.29  ? 131 TYR F O   1 
ATOM   16789 C CB  . TYR F 1 131 ? -22.933 12.640  77.208  1.00 26.32  ? 131 TYR F CB  1 
ATOM   16790 C CG  . TYR F 1 131 ? -22.125 11.974  78.293  1.00 32.88  ? 131 TYR F CG  1 
ATOM   16791 C CD1 . TYR F 1 131 ? -20.885 12.472  78.664  1.00 31.55  ? 131 TYR F CD1 1 
ATOM   16792 C CD2 . TYR F 1 131 ? -22.617 10.866  78.972  1.00 31.98  ? 131 TYR F CD2 1 
ATOM   16793 C CE1 . TYR F 1 131 ? -20.151 11.874  79.656  1.00 36.35  ? 131 TYR F CE1 1 
ATOM   16794 C CE2 . TYR F 1 131 ? -21.885 10.262  79.972  1.00 34.14  ? 131 TYR F CE2 1 
ATOM   16795 C CZ  . TYR F 1 131 ? -20.653 10.774  80.308  1.00 34.23  ? 131 TYR F CZ  1 
ATOM   16796 O OH  . TYR F 1 131 ? -19.914 10.181  81.295  1.00 41.38  ? 131 TYR F OH  1 
ATOM   16797 N N   . GLU F 1 132 ? -23.597 10.002  75.783  1.00 26.08  ? 132 GLU F N   1 
ATOM   16798 C CA  . GLU F 1 132 ? -23.553 8.547   75.768  1.00 27.67  ? 132 GLU F CA  1 
ATOM   16799 C C   . GLU F 1 132 ? -22.960 8.024   74.462  1.00 21.96  ? 132 GLU F C   1 
ATOM   16800 O O   . GLU F 1 132 ? -22.104 7.130   74.469  1.00 22.13  ? 132 GLU F O   1 
ATOM   16801 C CB  . GLU F 1 132 ? -24.954 7.984   76.010  1.00 24.37  ? 132 GLU F CB  1 
ATOM   16802 C CG  . GLU F 1 132 ? -25.526 8.345   77.369  1.00 25.84  ? 132 GLU F CG  1 
ATOM   16803 C CD  . GLU F 1 132 ? -24.692 7.797   78.528  1.00 35.42  ? 132 GLU F CD  1 
ATOM   16804 O OE1 . GLU F 1 132 ? -23.788 6.948   78.291  1.00 28.05  ? 132 GLU F OE1 1 
ATOM   16805 O OE2 . GLU F 1 132 ? -24.937 8.236   79.682  1.00 36.53  ? 132 GLU F OE2 1 
ATOM   16806 N N   . PHE F 1 133 ? -23.373 8.598   73.338  1.00 21.58  ? 133 PHE F N   1 
ATOM   16807 C CA  . PHE F 1 133 ? -22.777 8.234   72.054  1.00 23.14  ? 133 PHE F CA  1 
ATOM   16808 C C   . PHE F 1 133 ? -21.258 8.427   72.075  1.00 22.83  ? 133 PHE F C   1 
ATOM   16809 O O   . PHE F 1 133 ? -20.508 7.579   71.573  1.00 20.57  ? 133 PHE F O   1 
ATOM   16810 C CB  . PHE F 1 133 ? -23.453 9.061   70.951  1.00 20.43  ? 133 PHE F CB  1 
ATOM   16811 C CG  . PHE F 1 133 ? -23.055 8.695   69.541  1.00 25.64  ? 133 PHE F CG  1 
ATOM   16812 C CD1 . PHE F 1 133 ? -23.472 7.498   68.962  1.00 24.15  ? 133 PHE F CD1 1 
ATOM   16813 C CD2 . PHE F 1 133 ? -22.310 9.580   68.773  1.00 19.64  ? 133 PHE F CD2 1 
ATOM   16814 C CE1 . PHE F 1 133 ? -23.130 7.169   67.642  1.00 23.38  ? 133 PHE F CE1 1 
ATOM   16815 C CE2 . PHE F 1 133 ? -21.956 9.264   67.460  1.00 25.52  ? 133 PHE F CE2 1 
ATOM   16816 C CZ  . PHE F 1 133 ? -22.369 8.061   66.883  1.00 23.71  ? 133 PHE F CZ  1 
ATOM   16817 N N   . ALA F 1 134 ? -20.785 9.527   72.669  1.00 23.79  ? 134 ALA F N   1 
ATOM   16818 C CA  . ALA F 1 134 ? -19.351 9.800   72.695  1.00 23.13  ? 134 ALA F CA  1 
ATOM   16819 C C   . ALA F 1 134 ? -18.617 8.811   73.593  1.00 25.88  ? 134 ALA F C   1 
ATOM   16820 O O   . ALA F 1 134 ? -17.512 8.368   73.258  1.00 29.38  ? 134 ALA F O   1 
ATOM   16821 C CB  . ALA F 1 134 ? -19.091 11.237  73.157  1.00 26.92  ? 134 ALA F CB  1 
ATOM   16822 N N   . MET F 1 135 ? -19.232 8.434   74.723  1.00 27.20  ? 135 MET F N   1 
ATOM   16823 C CA  . MET F 1 135 ? -18.630 7.480   75.657  1.00 26.96  ? 135 MET F CA  1 
ATOM   16824 C C   . MET F 1 135 ? -18.402 6.102   75.038  1.00 27.47  ? 135 MET F C   1 
ATOM   16825 O O   . MET F 1 135 ? -17.536 5.346   75.504  1.00 29.94  ? 135 MET F O   1 
ATOM   16826 C CB  . MET F 1 135 ? -19.522 7.343   76.887  1.00 26.59  ? 135 MET F CB  1 
ATOM   16827 C CG  . MET F 1 135 ? -19.642 8.616   77.709  1.00 28.85  ? 135 MET F CG  1 
ATOM   16828 S SD  . MET F 1 135 ? -18.075 9.070   78.469  1.00 34.23  ? 135 MET F SD  1 
ATOM   16829 C CE  . MET F 1 135 ? -17.722 7.619   79.458  1.00 27.55  ? 135 MET F CE  1 
ATOM   16830 N N   . GLN F 1 136 ? -19.178 5.742   74.020  1.00 25.62  ? 136 GLN F N   1 
ATOM   16831 C CA  . GLN F 1 136 ? -18.983 4.489   73.298  1.00 27.07  ? 136 GLN F CA  1 
ATOM   16832 C C   . GLN F 1 136 ? -18.061 4.640   72.082  1.00 29.21  ? 136 GLN F C   1 
ATOM   16833 O O   . GLN F 1 136 ? -17.979 3.718   71.265  1.00 28.16  ? 136 GLN F O   1 
ATOM   16834 C CB  . GLN F 1 136 ? -20.340 3.931   72.857  1.00 21.68  ? 136 GLN F CB  1 
ATOM   16835 C CG  . GLN F 1 136 ? -21.277 3.555   74.029  1.00 20.27  ? 136 GLN F CG  1 
ATOM   16836 C CD  . GLN F 1 136 ? -20.636 2.592   75.006  1.00 22.89  ? 136 GLN F CD  1 
ATOM   16837 O OE1 . GLN F 1 136 ? -20.260 1.481   74.648  1.00 24.77  ? 136 GLN F OE1 1 
ATOM   16838 N NE2 . GLN F 1 136 ? -20.488 3.023   76.237  1.00 25.06  ? 136 GLN F NE2 1 
ATOM   16839 N N   . ASN F 1 137 ? -17.389 5.781   71.934  1.00 23.33  ? 137 ASN F N   1 
ATOM   16840 C CA  . ASN F 1 137 ? -16.570 6.067   70.749  1.00 33.64  ? 137 ASN F CA  1 
ATOM   16841 C C   . ASN F 1 137 ? -17.418 6.061   69.464  1.00 31.08  ? 137 ASN F C   1 
ATOM   16842 O O   . ASN F 1 137 ? -16.969 5.630   68.397  1.00 25.83  ? 137 ASN F O   1 
ATOM   16843 C CB  . ASN F 1 137 ? -15.374 5.094   70.619  1.00 31.74  ? 137 ASN F CB  1 
ATOM   16844 C CG  . ASN F 1 137 ? -14.656 4.808   71.963  1.00 38.29  ? 137 ASN F CG  1 
ATOM   16845 O OD1 . ASN F 1 137 ? -14.498 3.642   72.369  1.00 37.01  ? 137 ASN F OD1 1 
ATOM   16846 N ND2 . ASN F 1 137 ? -14.205 5.863   72.635  1.00 28.12  ? 137 ASN F ND2 1 
ATOM   16847 N N   . GLY F 1 138 ? -18.652 6.565   69.554  1.00 27.10  ? 138 GLY F N   1 
ATOM   16848 C CA  . GLY F 1 138 ? -19.540 6.499   68.402  1.00 25.29  ? 138 GLY F CA  1 
ATOM   16849 C C   . GLY F 1 138 ? -19.032 7.312   67.233  1.00 28.62  ? 138 GLY F C   1 
ATOM   16850 O O   . GLY F 1 138 ? -19.308 6.986   66.069  1.00 20.80  ? 138 GLY F O   1 
ATOM   16851 N N   . ILE F 1 139 ? -18.272 8.372   67.530  1.00 27.41  ? 139 ILE F N   1 
ATOM   16852 C CA  . ILE F 1 139 ? -17.710 9.228   66.503  1.00 28.17  ? 139 ILE F CA  1 
ATOM   16853 C C   . ILE F 1 139 ? -16.739 8.464   65.625  1.00 32.98  ? 139 ILE F C   1 
ATOM   16854 O O   . ILE F 1 139 ? -16.629 8.749   64.425  1.00 29.44  ? 139 ILE F O   1 
ATOM   16855 C CB  . ILE F 1 139 ? -17.052 10.452  67.153  1.00 29.79  ? 139 ILE F CB  1 
ATOM   16856 C CG1 . ILE F 1 139 ? -18.138 11.482  67.469  1.00 29.38  ? 139 ILE F CG1 1 
ATOM   16857 C CG2 . ILE F 1 139 ? -15.968 11.050  66.230  1.00 28.13  ? 139 ILE F CG2 1 
ATOM   16858 C CD1 . ILE F 1 139 ? -19.000 11.154  68.679  1.00 26.59  ? 139 ILE F CD1 1 
ATOM   16859 N N   . ASP F 1 140 ? -16.030 7.484   66.197  1.00 33.37  ? 140 ASP F N   1 
ATOM   16860 C CA  . ASP F 1 140 ? -15.097 6.681   65.421  1.00 31.23  ? 140 ASP F CA  1 
ATOM   16861 C C   . ASP F 1 140 ? -15.818 5.813   64.400  1.00 32.63  ? 140 ASP F C   1 
ATOM   16862 O O   . ASP F 1 140 ? -15.244 5.508   63.349  1.00 36.53  ? 140 ASP F O   1 
ATOM   16863 C CB  . ASP F 1 140 ? -14.255 5.801   66.349  1.00 34.81  ? 140 ASP F CB  1 
ATOM   16864 C CG  . ASP F 1 140 ? -13.096 6.560   67.000  1.00 43.24  ? 140 ASP F CG  1 
ATOM   16865 O OD1 . ASP F 1 140 ? -12.511 7.457   66.353  1.00 43.86  ? 140 ASP F OD1 1 
ATOM   16866 O OD2 . ASP F 1 140 ? -12.772 6.263   68.171  1.00 41.12  ? 140 ASP F OD2 1 
ATOM   16867 N N   . LEU F 1 141 ? -17.063 5.406   64.694  1.00 31.90  ? 141 LEU F N   1 
ATOM   16868 C CA  . LEU F 1 141 ? -17.873 4.633   63.748  1.00 27.70  ? 141 LEU F CA  1 
ATOM   16869 C C   . LEU F 1 141 ? -18.143 5.442   62.481  1.00 27.70  ? 141 LEU F C   1 
ATOM   16870 O O   . LEU F 1 141 ? -17.782 5.037   61.367  1.00 23.96  ? 141 LEU F O   1 
ATOM   16871 C CB  . LEU F 1 141 ? -19.193 4.212   64.400  1.00 24.19  ? 141 LEU F CB  1 
ATOM   16872 C CG  . LEU F 1 141 ? -20.143 3.353   63.552  1.00 25.30  ? 141 LEU F CG  1 
ATOM   16873 C CD1 . LEU F 1 141 ? -19.403 2.180   62.963  1.00 29.74  ? 141 LEU F CD1 1 
ATOM   16874 C CD2 . LEU F 1 141 ? -21.288 2.863   64.385  1.00 27.88  ? 141 LEU F CD2 1 
ATOM   16875 N N   . LEU F 1 142 ? -18.793 6.587   62.634  1.00 25.69  ? 142 LEU F N   1 
ATOM   16876 C CA  . LEU F 1 142 ? -18.740 7.593   61.597  1.00 26.28  ? 142 LEU F CA  1 
ATOM   16877 C C   . LEU F 1 142 ? -17.273 7.973   61.445  1.00 30.50  ? 142 LEU F C   1 
ATOM   16878 O O   . LEU F 1 142 ? -16.439 7.563   62.232  1.00 41.41  ? 142 LEU F O   1 
ATOM   16879 C CB  . LEU F 1 142 ? -19.633 8.771   61.983  1.00 27.22  ? 142 LEU F CB  1 
ATOM   16880 C CG  . LEU F 1 142 ? -20.811 8.360   62.884  1.00 21.26  ? 142 LEU F CG  1 
ATOM   16881 C CD1 . LEU F 1 142 ? -21.540 9.587   63.395  1.00 26.48  ? 142 LEU F CD1 1 
ATOM   16882 C CD2 . LEU F 1 142 ? -21.780 7.454   62.162  1.00 23.40  ? 142 LEU F CD2 1 
ATOM   16883 N N   . ASN F 1 143 ? -16.930 8.704   60.410  1.00 29.76  ? 143 ASN F N   1 
ATOM   16884 C CA  . ASN F 1 143 ? -15.532 9.052   60.147  1.00 29.86  ? 143 ASN F CA  1 
ATOM   16885 C C   . ASN F 1 143 ? -14.751 7.866   59.583  1.00 29.96  ? 143 ASN F C   1 
ATOM   16886 O O   . ASN F 1 143 ? -13.538 8.009   59.349  1.00 32.53  ? 143 ASN F O   1 
ATOM   16887 C CB  . ASN F 1 143 ? -14.758 9.564   61.378  1.00 32.42  ? 143 ASN F CB  1 
ATOM   16888 C CG  . ASN F 1 143 ? -15.166 10.947  61.806  1.00 27.49  ? 143 ASN F CG  1 
ATOM   16889 O OD1 . ASN F 1 143 ? -15.898 11.643  61.107  1.00 32.48  ? 143 ASN F OD1 1 
ATOM   16890 N ND2 . ASN F 1 143 ? -14.678 11.363  62.960  1.00 26.11  ? 143 ASN F ND2 1 
ATOM   16891 N N   . MET F 1 144 ? -15.360 6.697   59.419  1.00 27.20  ? 144 MET F N   1 
ATOM   16892 C CA  . MET F 1 144 ? -14.765 5.626   58.634  1.00 26.24  ? 144 MET F CA  1 
ATOM   16893 C C   . MET F 1 144 ? -15.352 5.703   57.235  1.00 23.49  ? 144 MET F C   1 
ATOM   16894 O O   . MET F 1 144 ? -16.571 5.807   57.070  1.00 20.90  ? 144 MET F O   1 
ATOM   16895 C CB  . MET F 1 144 ? -15.043 4.244   59.223  1.00 24.34  ? 144 MET F CB  1 
ATOM   16896 C CG  . MET F 1 144 ? -14.335 3.909   60.522  1.00 28.38  ? 144 MET F CG  1 
ATOM   16897 S SD  . MET F 1 144 ? -15.147 2.499   61.318  1.00 35.80  ? 144 MET F SD  1 
ATOM   16898 C CE  . MET F 1 144 ? -14.264 1.158   60.520  1.00 33.02  ? 144 MET F CE  1 
ATOM   16899 N N   . LYS F 1 145 ? -14.493 5.640   56.227  1.00 22.51  ? 145 LYS F N   1 
ATOM   16900 C CA  . LYS F 1 145 ? -15.006 5.685   54.869  1.00 25.19  ? 145 LYS F CA  1 
ATOM   16901 C C   . LYS F 1 145 ? -15.923 4.505   54.588  1.00 22.49  ? 145 LYS F C   1 
ATOM   16902 O O   . LYS F 1 145 ? -16.909 4.645   53.848  1.00 20.19  ? 145 LYS F O   1 
ATOM   16903 C CB  . LYS F 1 145 ? -13.846 5.745   53.879  1.00 25.15  ? 145 LYS F CB  1 
ATOM   16904 C CG  . LYS F 1 145 ? -13.055 7.020   54.107  1.00 26.47  ? 145 LYS F CG  1 
ATOM   16905 C CD  . LYS F 1 145 ? -12.010 7.233   53.079  1.00 26.22  ? 145 LYS F CD  1 
ATOM   16906 C CE  . LYS F 1 145 ? -11.334 8.571   53.329  1.00 30.88  ? 145 LYS F CE  1 
ATOM   16907 N NZ  . LYS F 1 145 ? -10.507 8.539   54.555  1.00 33.65  ? 145 LYS F NZ  1 
ATOM   16908 N N   . SER F 1 146 ? -15.634 3.349   55.182  1.00 19.43  ? 146 SER F N   1 
ATOM   16909 C CA  . SER F 1 146 ? -16.470 2.183   54.938  1.00 20.80  ? 146 SER F CA  1 
ATOM   16910 C C   . SER F 1 146 ? -17.880 2.417   55.468  1.00 21.89  ? 146 SER F C   1 
ATOM   16911 O O   . SER F 1 146 ? -18.869 1.988   54.857  1.00 20.64  ? 146 SER F O   1 
ATOM   16912 C CB  . SER F 1 146 ? -15.846 0.957   55.600  1.00 19.66  ? 146 SER F CB  1 
ATOM   16913 O OG  . SER F 1 146 ? -15.593 1.218   56.972  1.00 23.65  ? 146 SER F OG  1 
ATOM   16914 N N   . THR F 1 147 ? -17.978 3.089   56.616  1.00 18.55  ? 147 THR F N   1 
ATOM   16915 C CA  . THR F 1 147 ? -19.265 3.374   57.233  1.00 18.05  ? 147 THR F CA  1 
ATOM   16916 C C   . THR F 1 147 ? -20.075 4.318   56.373  1.00 16.81  ? 147 THR F C   1 
ATOM   16917 O O   . THR F 1 147 ? -21.292 4.161   56.262  1.00 20.82  ? 147 THR F O   1 
ATOM   16918 C CB  . THR F 1 147 ? -19.059 3.985   58.619  1.00 24.74  ? 147 THR F CB  1 
ATOM   16919 O OG1 . THR F 1 147 ? -18.419 3.037   59.484  1.00 23.27  ? 147 THR F OG1 1 
ATOM   16920 C CG2 . THR F 1 147 ? -20.402 4.420   59.217  1.00 24.26  ? 147 THR F CG2 1 
ATOM   16921 N N   . PHE F 1 148 ? -19.419 5.313   55.761  1.00 20.07  ? 148 PHE F N   1 
ATOM   16922 C CA  . PHE F 1 148 ? -20.127 6.207   54.848  1.00 19.91  ? 148 PHE F CA  1 
ATOM   16923 C C   . PHE F 1 148 ? -20.698 5.450   53.651  1.00 19.16  ? 148 PHE F C   1 
ATOM   16924 O O   . PHE F 1 148 ? -21.844 5.681   53.247  1.00 19.34  ? 148 PHE F O   1 
ATOM   16925 C CB  . PHE F 1 148 ? -19.214 7.320   54.352  1.00 16.03  ? 148 PHE F CB  1 
ATOM   16926 C CG  . PHE F 1 148 ? -19.871 8.197   53.335  1.00 20.15  ? 148 PHE F CG  1 
ATOM   16927 C CD1 . PHE F 1 148 ? -20.833 9.128   53.721  1.00 24.52  ? 148 PHE F CD1 1 
ATOM   16928 C CD2 . PHE F 1 148 ? -19.580 8.060   51.984  1.00 22.47  ? 148 PHE F CD2 1 
ATOM   16929 C CE1 . PHE F 1 148 ? -21.489 9.937   52.764  1.00 21.37  ? 148 PHE F CE1 1 
ATOM   16930 C CE2 . PHE F 1 148 ? -20.221 8.858   51.027  1.00 24.80  ? 148 PHE F CE2 1 
ATOM   16931 C CZ  . PHE F 1 148 ? -21.172 9.806   51.421  1.00 20.62  ? 148 PHE F CZ  1 
ATOM   16932 N N   . ARG F 1 149 ? -19.891 4.593   53.024  1.00 20.55  ? 149 ARG F N   1 
ATOM   16933 C CA  . ARG F 1 149 ? -20.396 3.813   51.895  1.00 19.46  ? 149 ARG F CA  1 
ATOM   16934 C C   . ARG F 1 149 ? -21.595 2.969   52.310  1.00 19.15  ? 149 ARG F C   1 
ATOM   16935 O O   . ARG F 1 149 ? -22.578 2.853   51.566  1.00 17.67  ? 149 ARG F O   1 
ATOM   16936 C CB  . ARG F 1 149 ? -19.288 2.924   51.335  1.00 18.96  ? 149 ARG F CB  1 
ATOM   16937 C CG  . ARG F 1 149 ? -18.139 3.700   50.678  1.00 22.86  ? 149 ARG F CG  1 
ATOM   16938 C CD  . ARG F 1 149 ? -17.369 2.846   49.655  1.00 23.63  ? 149 ARG F CD  1 
ATOM   16939 N NE  . ARG F 1 149 ? -18.212 2.359   48.574  1.00 22.99  ? 149 ARG F NE  1 
ATOM   16940 C CZ  . ARG F 1 149 ? -18.544 3.057   47.489  1.00 23.74  ? 149 ARG F CZ  1 
ATOM   16941 N NH1 . ARG F 1 149 ? -18.147 4.311   47.315  1.00 19.63  ? 149 ARG F NH1 1 
ATOM   16942 N NH2 . ARG F 1 149 ? -19.300 2.484   46.558  1.00 18.82  ? 149 ARG F NH2 1 
ATOM   16943 N N   . ARG F 1 150 ? -21.530 2.385   53.508  1.00 18.41  ? 150 ARG F N   1 
ATOM   16944 C CA  . ARG F 1 150 ? -22.584 1.499   53.972  1.00 16.17  ? 150 ARG F CA  1 
ATOM   16945 C C   . ARG F 1 150 ? -23.862 2.282   54.236  1.00 18.30  ? 150 ARG F C   1 
ATOM   16946 O O   . ARG F 1 150 ? -24.911 1.989   53.642  1.00 18.85  ? 150 ARG F O   1 
ATOM   16947 C CB  . ARG F 1 150 ? -22.103 0.753   55.221  1.00 16.59  ? 150 ARG F CB  1 
ATOM   16948 C CG  . ARG F 1 150 ? -21.171 -0.405  54.890  1.00 15.96  ? 150 ARG F CG  1 
ATOM   16949 C CD  . ARG F 1 150 ? -20.182 -0.715  55.999  1.00 19.75  ? 150 ARG F CD  1 
ATOM   16950 N NE  . ARG F 1 150 ? -19.521 -1.983  55.720  1.00 22.18  ? 150 ARG F NE  1 
ATOM   16951 C CZ  . ARG F 1 150 ? -18.655 -2.585  56.522  1.00 25.90  ? 150 ARG F CZ  1 
ATOM   16952 N NH1 . ARG F 1 150 ? -18.278 -2.039  57.671  1.00 21.44  ? 150 ARG F NH1 1 
ATOM   16953 N NH2 . ARG F 1 150 ? -18.170 -3.774  56.172  1.00 23.05  ? 150 ARG F NH2 1 
ATOM   16954 N N   . LEU F 1 151 ? -23.769 3.341   55.057  1.00 19.05  ? 151 LEU F N   1 
ATOM   16955 C CA  . LEU F 1 151 ? -24.927 4.189   55.323  1.00 18.08  ? 151 LEU F CA  1 
ATOM   16956 C C   . LEU F 1 151 ? -25.491 4.776   54.042  1.00 20.28  ? 151 LEU F C   1 
ATOM   16957 O O   . LEU F 1 151 ? -26.714 4.843   53.877  1.00 21.34  ? 151 LEU F O   1 
ATOM   16958 C CB  . LEU F 1 151 ? -24.562 5.322   56.293  1.00 20.30  ? 151 LEU F CB  1 
ATOM   16959 C CG  . LEU F 1 151 ? -24.141 4.889   57.709  1.00 25.59  ? 151 LEU F CG  1 
ATOM   16960 C CD1 . LEU F 1 151 ? -24.160 6.077   58.676  1.00 23.82  ? 151 LEU F CD1 1 
ATOM   16961 C CD2 . LEU F 1 151 ? -24.986 3.729   58.235  1.00 22.85  ? 151 LEU F CD2 1 
ATOM   16962 N N   . ALA F 1 152 ? -24.624 5.220   53.123  1.00 15.09  ? 152 ALA F N   1 
ATOM   16963 C CA  . ALA F 1 152 ? -25.165 5.912   51.961  1.00 21.39  ? 152 ALA F CA  1 
ATOM   16964 C C   . ALA F 1 152 ? -25.781 4.923   50.981  1.00 19.19  ? 152 ALA F C   1 
ATOM   16965 O O   . ALA F 1 152 ? -26.805 5.218   50.378  1.00 16.51  ? 152 ALA F O   1 
ATOM   16966 C CB  . ALA F 1 152 ? -24.096 6.762   51.266  1.00 17.76  ? 152 ALA F CB  1 
ATOM   16967 N N   . ALA F 1 153 ? -25.174 3.746   50.817  1.00 20.81  ? 153 ALA F N   1 
ATOM   16968 C CA  . ALA F 1 153 ? -25.786 2.719   49.977  1.00 18.62  ? 153 ALA F CA  1 
ATOM   16969 C C   . ALA F 1 153 ? -27.131 2.301   50.544  1.00 22.67  ? 153 ALA F C   1 
ATOM   16970 O O   . ALA F 1 153 ? -28.104 2.137   49.798  1.00 23.61  ? 153 ALA F O   1 
ATOM   16971 C CB  . ALA F 1 153 ? -24.864 1.507   49.849  1.00 18.93  ? 153 ALA F CB  1 
ATOM   16972 N N   . GLY F 1 154 ? -27.216 2.174   51.871  1.00 19.00  ? 154 GLY F N   1 
ATOM   16973 C CA  . GLY F 1 154 ? -28.471 1.781   52.479  1.00 22.14  ? 154 GLY F CA  1 
ATOM   16974 C C   . GLY F 1 154 ? -29.543 2.840   52.326  1.00 23.43  ? 154 GLY F C   1 
ATOM   16975 O O   . GLY F 1 154 ? -30.711 2.524   52.099  1.00 23.98  ? 154 GLY F O   1 
ATOM   16976 N N   . LEU F 1 155 ? -29.154 4.108   52.409  1.00 20.19  ? 155 LEU F N   1 
ATOM   16977 C CA  . LEU F 1 155 ? -30.136 5.182   52.416  1.00 22.40  ? 155 LEU F CA  1 
ATOM   16978 C C   . LEU F 1 155 ? -30.580 5.541   51.016  1.00 23.94  ? 155 LEU F C   1 
ATOM   16979 O O   . LEU F 1 155 ? -31.707 5.999   50.836  1.00 27.69  ? 155 LEU F O   1 
ATOM   16980 C CB  . LEU F 1 155 ? -29.545 6.404   53.101  1.00 23.44  ? 155 LEU F CB  1 
ATOM   16981 C CG  . LEU F 1 155 ? -30.332 7.214   54.117  1.00 26.90  ? 155 LEU F CG  1 
ATOM   16982 C CD1 . LEU F 1 155 ? -29.745 8.601   54.109  1.00 22.86  ? 155 LEU F CD1 1 
ATOM   16983 C CD2 . LEU F 1 155 ? -31.829 7.266   53.827  1.00 29.53  ? 155 LEU F CD2 1 
ATOM   16984 N N   . GLY F 1 156 ? -29.717 5.326   50.023  1.00 25.26  ? 156 GLY F N   1 
ATOM   16985 C CA  . GLY F 1 156 ? -29.952 5.743   48.654  1.00 22.33  ? 156 GLY F CA  1 
ATOM   16986 C C   . GLY F 1 156 ? -29.179 6.969   48.228  1.00 25.81  ? 156 GLY F C   1 
ATOM   16987 O O   . GLY F 1 156 ? -29.418 7.481   47.127  1.00 24.82  ? 156 GLY F O   1 
ATOM   16988 N N   . THR F 1 157 ? -28.274 7.461   49.070  1.00 26.18  ? 157 THR F N   1 
ATOM   16989 C CA  . THR F 1 157 ? -27.493 8.645   48.749  1.00 22.72  ? 157 THR F CA  1 
ATOM   16990 C C   . THR F 1 157 ? -26.601 8.362   47.538  1.00 28.68  ? 157 THR F C   1 
ATOM   16991 O O   . THR F 1 157 ? -26.029 7.280   47.438  1.00 22.16  ? 157 THR F O   1 
ATOM   16992 C CB  . THR F 1 157 ? -26.654 9.034   49.970  1.00 19.99  ? 157 THR F CB  1 
ATOM   16993 O OG1 . THR F 1 157 ? -27.486 8.972   51.139  1.00 24.99  ? 157 THR F OG1 1 
ATOM   16994 C CG2 . THR F 1 157 ? -26.086 10.419  49.849  1.00 23.17  ? 157 THR F CG2 1 
ATOM   16995 N N   . PRO F 1 158 ? -26.485 9.304   46.596  1.00 29.43  ? 158 PRO F N   1 
ATOM   16996 C CA  . PRO F 1 158 ? -25.683 9.060   45.381  1.00 25.54  ? 158 PRO F CA  1 
ATOM   16997 C C   . PRO F 1 158 ? -24.223 8.782   45.704  1.00 27.35  ? 158 PRO F C   1 
ATOM   16998 O O   . PRO F 1 158 ? -23.531 9.627   46.273  1.00 26.22  ? 158 PRO F O   1 
ATOM   16999 C CB  . PRO F 1 158 ? -25.833 10.367  44.594  1.00 27.57  ? 158 PRO F CB  1 
ATOM   17000 C CG  . PRO F 1 158 ? -27.074 11.028  45.139  1.00 27.88  ? 158 PRO F CG  1 
ATOM   17001 C CD  . PRO F 1 158 ? -27.130 10.631  46.583  1.00 26.62  ? 158 PRO F CD  1 
ATOM   17002 N N   . LEU F 1 159 ? -23.754 7.601   45.296  1.00 29.54  ? 159 LEU F N   1 
ATOM   17003 C CA  . LEU F 1 159 ? -22.425 7.065   45.588  1.00 27.85  ? 159 LEU F CA  1 
ATOM   17004 C C   . LEU F 1 159 ? -21.697 6.682   44.309  1.00 27.62  ? 159 LEU F C   1 
ATOM   17005 O O   . LEU F 1 159 ? -22.292 6.068   43.422  1.00 30.26  ? 159 LEU F O   1 
ATOM   17006 C CB  . LEU F 1 159 ? -22.529 5.784   46.401  1.00 29.02  ? 159 LEU F CB  1 
ATOM   17007 C CG  . LEU F 1 159 ? -22.452 5.784   47.904  1.00 29.89  ? 159 LEU F CG  1 
ATOM   17008 C CD1 . LEU F 1 159 ? -22.450 4.319   48.344  1.00 27.21  ? 159 LEU F CD1 1 
ATOM   17009 C CD2 . LEU F 1 159 ? -21.200 6.482   48.337  1.00 27.37  ? 159 LEU F CD2 1 
ATOM   17010 N N   . THR F 1 160 ? -20.393 6.947   44.236  1.00 28.49  ? 160 THR F N   1 
ATOM   17011 C CA  . THR F 1 160 ? -19.628 6.331   43.161  1.00 26.39  ? 160 THR F CA  1 
ATOM   17012 C C   . THR F 1 160 ? -19.522 4.827   43.412  1.00 27.21  ? 160 THR F C   1 
ATOM   17013 O O   . THR F 1 160 ? -19.544 4.351   44.558  1.00 23.79  ? 160 THR F O   1 
ATOM   17014 C CB  . THR F 1 160 ? -18.228 6.973   43.005  1.00 27.67  ? 160 THR F CB  1 
ATOM   17015 O OG1 . THR F 1 160 ? -17.356 6.592   44.085  1.00 28.14  ? 160 THR F OG1 1 
ATOM   17016 C CG2 . THR F 1 160 ? -18.335 8.471   42.981  1.00 24.91  ? 160 THR F CG2 1 
ATOM   17017 N N   . ASP F 1 161 ? -19.445 4.065   42.326  1.00 25.46  ? 161 ASP F N   1 
ATOM   17018 C CA  . ASP F 1 161 ? -19.227 2.633   42.481  1.00 25.88  ? 161 ASP F CA  1 
ATOM   17019 C C   . ASP F 1 161 ? -17.940 2.397   43.265  1.00 19.97  ? 161 ASP F C   1 
ATOM   17020 O O   . ASP F 1 161 ? -16.949 3.106   43.083  1.00 24.67  ? 161 ASP F O   1 
ATOM   17021 C CB  . ASP F 1 161 ? -19.135 1.958   41.110  1.00 28.60  ? 161 ASP F CB  1 
ATOM   17022 C CG  . ASP F 1 161 ? -20.501 1.669   40.494  1.00 35.32  ? 161 ASP F CG  1 
ATOM   17023 O OD1 . ASP F 1 161 ? -21.527 2.185   40.997  1.00 28.12  ? 161 ASP F OD1 1 
ATOM   17024 O OD2 . ASP F 1 161 ? -20.535 0.924   39.488  1.00 44.01  ? 161 ASP F OD2 1 
ATOM   17025 N N   . GLY F 1 162 ? -17.949 1.400   44.131  1.00 18.23  ? 162 GLY F N   1 
ATOM   17026 C CA  . GLY F 1 162 ? -16.769 1.099   44.918  1.00 20.68  ? 162 GLY F CA  1 
ATOM   17027 C C   . GLY F 1 162 ? -17.041 -0.083  45.821  1.00 25.81  ? 162 GLY F C   1 
ATOM   17028 O O   . GLY F 1 162 ? -18.164 -0.606  45.877  1.00 22.35  ? 162 GLY F O   1 
ATOM   17029 N N   . VAL F 1 163 ? -15.980 -0.522  46.511  1.00 21.81  ? 163 VAL F N   1 
ATOM   17030 C CA  . VAL F 1 163 ? -16.055 -1.689  47.384  1.00 24.05  ? 163 VAL F CA  1 
ATOM   17031 C C   . VAL F 1 163 ? -15.289 -1.451  48.691  1.00 24.16  ? 163 VAL F C   1 
ATOM   17032 O O   . VAL F 1 163 ? -14.268 -0.753  48.739  1.00 20.59  ? 163 VAL F O   1 
ATOM   17033 C CB  . VAL F 1 163 ? -15.568 -3.001  46.677  1.00 27.05  ? 163 VAL F CB  1 
ATOM   17034 C CG1 . VAL F 1 163 ? -15.591 -2.891  45.147  1.00 23.14  ? 163 VAL F CG1 1 
ATOM   17035 C CG2 . VAL F 1 163 ? -14.224 -3.469  47.200  1.00 24.66  ? 163 VAL F CG2 1 
ATOM   17036 N N   . VAL F 1 164 ? -15.813 -2.028  49.771  1.00 20.51  ? 164 VAL F N   1 
ATOM   17037 C CA  . VAL F 1 164 ? -15.120 -2.043  51.049  1.00 16.61  ? 164 VAL F CA  1 
ATOM   17038 C C   . VAL F 1 164 ? -14.236 -3.288  51.028  1.00 21.61  ? 164 VAL F C   1 
ATOM   17039 O O   . VAL F 1 164 ? -14.667 -4.397  51.347  1.00 20.20  ? 164 VAL F O   1 
ATOM   17040 C CB  . VAL F 1 164 ? -16.095 -2.010  52.218  1.00 19.22  ? 164 VAL F CB  1 
ATOM   17041 C CG1 . VAL F 1 164 ? -15.353 -2.023  53.566  1.00 15.76  ? 164 VAL F CG1 1 
ATOM   17042 C CG2 . VAL F 1 164 ? -16.949 -0.737  52.095  1.00 19.75  ? 164 VAL F CG2 1 
ATOM   17043 N N   . ALA F 1 165 ? -12.982 -3.096  50.609  1.00 19.44  ? 165 ALA F N   1 
ATOM   17044 C CA  . ALA F 1 165 ? -12.047 -4.194  50.400  1.00 25.90  ? 165 ALA F CA  1 
ATOM   17045 C C   . ALA F 1 165 ? -11.522 -4.746  51.716  1.00 19.27  ? 165 ALA F C   1 
ATOM   17046 O O   . ALA F 1 165 ? -11.181 -3.990  52.623  1.00 19.54  ? 165 ALA F O   1 
ATOM   17047 C CB  . ALA F 1 165 ? -10.861 -3.737  49.537  1.00 22.76  ? 165 ALA F CB  1 
ATOM   17048 N N   . ARG F 1 166 ? -11.401 -6.075  51.784  1.00 19.21  ? 166 ARG F N   1 
ATOM   17049 C CA  . ARG F 1 166 ? -11.020 -6.791  52.994  1.00 23.22  ? 166 ARG F CA  1 
ATOM   17050 C C   . ARG F 1 166 ? -9.658  -7.471  52.908  1.00 22.93  ? 166 ARG F C   1 
ATOM   17051 O O   . ARG F 1 166 ? -9.206  -8.055  53.899  1.00 25.99  ? 166 ARG F O   1 
ATOM   17052 C CB  . ARG F 1 166 ? -12.088 -7.846  53.335  1.00 21.44  ? 166 ARG F CB  1 
ATOM   17053 C CG  . ARG F 1 166 ? -13.421 -7.234  53.734  1.00 22.42  ? 166 ARG F CG  1 
ATOM   17054 C CD  . ARG F 1 166 ? -14.542 -8.260  53.636  1.00 29.54  ? 166 ARG F CD  1 
ATOM   17055 N NE  . ARG F 1 166 ? -14.919 -8.543  52.252  1.00 27.63  ? 166 ARG F NE  1 
ATOM   17056 C CZ  . ARG F 1 166 ? -15.903 -9.362  51.902  1.00 30.71  ? 166 ARG F CZ  1 
ATOM   17057 N NH1 . ARG F 1 166 ? -16.631 -9.991  52.810  1.00 32.37  ? 166 ARG F NH1 1 
ATOM   17058 N NH2 . ARG F 1 166 ? -16.163 -9.557  50.608  1.00 30.43  ? 166 ARG F NH2 1 
ATOM   17059 N N   . GLY F 1 167 ? -9.004  -7.445  51.765  1.00 23.85  ? 167 GLY F N   1 
ATOM   17060 C CA  . GLY F 1 167 ? -7.660  -7.959  51.679  1.00 22.08  ? 167 GLY F CA  1 
ATOM   17061 C C   . GLY F 1 167 ? -7.070  -7.571  50.353  1.00 20.99  ? 167 GLY F C   1 
ATOM   17062 O O   . GLY F 1 167 ? -7.757  -7.002  49.501  1.00 26.71  ? 167 GLY F O   1 
ATOM   17063 N N   . PRO F 1 168 ? -5.799  -7.882  50.130  1.00 22.78  ? 168 PRO F N   1 
ATOM   17064 C CA  . PRO F 1 168 ? -5.201  -7.505  48.840  1.00 26.67  ? 168 PRO F CA  1 
ATOM   17065 C C   . PRO F 1 168 ? -5.909  -8.151  47.659  1.00 23.42  ? 168 PRO F C   1 
ATOM   17066 O O   . PRO F 1 168 ? -6.039  -7.511  46.610  1.00 22.11  ? 168 PRO F O   1 
ATOM   17067 C CB  . PRO F 1 168 ? -3.736  -7.956  48.968  1.00 30.90  ? 168 PRO F CB  1 
ATOM   17068 C CG  . PRO F 1 168 ? -3.675  -8.852  50.176  1.00 22.48  ? 168 PRO F CG  1 
ATOM   17069 C CD  . PRO F 1 168 ? -4.840  -8.519  51.050  1.00 29.10  ? 168 PRO F CD  1 
ATOM   17070 N N   . ALA F 1 169 ? -6.434  -9.374  47.811  1.00 24.27  ? 169 ALA F N   1 
ATOM   17071 C CA  . ALA F 1 169 ? -7.125  -10.008 46.691  1.00 18.63  ? 169 ALA F CA  1 
ATOM   17072 C C   . ALA F 1 169 ? -8.412  -9.273  46.339  1.00 24.37  ? 169 ALA F C   1 
ATOM   17073 O O   . ALA F 1 169 ? -8.759  -9.172  45.156  1.00 24.93  ? 169 ALA F O   1 
ATOM   17074 C CB  . ALA F 1 169 ? -7.411  -11.480 46.990  1.00 23.09  ? 169 ALA F CB  1 
ATOM   17075 N N   . GLU F 1 170 ? -9.112  -8.715  47.333  1.00 24.70  ? 170 GLU F N   1 
ATOM   17076 C CA  . GLU F 1 170 ? -10.292 -7.914  47.015  1.00 24.63  ? 170 GLU F CA  1 
ATOM   17077 C C   . GLU F 1 170 ? -9.907  -6.520  46.528  1.00 22.74  ? 170 GLU F C   1 
ATOM   17078 O O   . GLU F 1 170 ? -10.612 -5.939  45.700  1.00 21.79  ? 170 GLU F O   1 
ATOM   17079 C CB  . GLU F 1 170 ? -11.240 -7.822  48.218  1.00 24.27  ? 170 GLU F CB  1 
ATOM   17080 C CG  . GLU F 1 170 ? -12.693 -7.560  47.797  1.00 28.58  ? 170 GLU F CG  1 
ATOM   17081 C CD  . GLU F 1 170 ? -13.704 -7.661  48.940  1.00 26.02  ? 170 GLU F CD  1 
ATOM   17082 O OE1 . GLU F 1 170 ? -13.310 -7.612  50.124  1.00 26.27  ? 170 GLU F OE1 1 
ATOM   17083 O OE2 . GLU F 1 170 ? -14.910 -7.774  48.646  1.00 29.50  ? 170 GLU F OE2 1 
ATOM   17084 N N   . VAL F 1 171 ? -8.795  -5.972  47.000  1.00 21.48  ? 171 VAL F N   1 
ATOM   17085 C CA  . VAL F 1 171 ? -8.271  -4.776  46.357  1.00 21.67  ? 171 VAL F CA  1 
ATOM   17086 C C   . VAL F 1 171 ? -8.024  -5.033  44.870  1.00 26.28  ? 171 VAL F C   1 
ATOM   17087 O O   . VAL F 1 171 ? -8.374  -4.210  44.015  1.00 24.30  ? 171 VAL F O   1 
ATOM   17088 C CB  . VAL F 1 171 ? -6.996  -4.304  47.064  1.00 21.59  ? 171 VAL F CB  1 
ATOM   17089 C CG1 . VAL F 1 171 ? -6.352  -3.173  46.245  1.00 17.36  ? 171 VAL F CG1 1 
ATOM   17090 C CG2 . VAL F 1 171 ? -7.336  -3.843  48.506  1.00 19.51  ? 171 VAL F CG2 1 
ATOM   17091 N N   . ARG F 1 172 ? -7.458  -6.194  44.540  1.00 26.83  ? 172 ARG F N   1 
ATOM   17092 C CA  . ARG F 1 172 ? -7.068  -6.475  43.159  1.00 30.45  ? 172 ARG F CA  1 
ATOM   17093 C C   . ARG F 1 172 ? -8.284  -6.551  42.236  1.00 26.57  ? 172 ARG F C   1 
ATOM   17094 O O   . ARG F 1 172 ? -8.287  -5.971  41.143  1.00 25.31  ? 172 ARG F O   1 
ATOM   17095 C CB  . ARG F 1 172 ? -6.261  -7.779  43.107  1.00 27.90  ? 172 ARG F CB  1 
ATOM   17096 C CG  . ARG F 1 172 ? -5.982  -8.245  41.704  1.00 36.97  ? 172 ARG F CG  1 
ATOM   17097 C CD  . ARG F 1 172 ? -5.653  -9.735  41.628  1.00 43.21  ? 172 ARG F CD  1 
ATOM   17098 N NE  . ARG F 1 172 ? -6.507  -10.385 40.640  1.00 50.80  ? 172 ARG F NE  1 
ATOM   17099 C CZ  . ARG F 1 172 ? -7.697  -10.913 40.909  1.00 52.52  ? 172 ARG F CZ  1 
ATOM   17100 N NH1 . ARG F 1 172 ? -8.175  -10.957 42.152  1.00 42.16  ? 172 ARG F NH1 1 
ATOM   17101 N NH2 . ARG F 1 172 ? -8.429  -11.407 39.909  1.00 46.58  ? 172 ARG F NH2 1 
ATOM   17102 N N   . SER F 1 173 ? -9.329  -7.264  42.657  1.00 21.60  ? 173 SER F N   1 
ATOM   17103 C CA  . SER F 1 173 ? -10.490 -7.408  41.786  1.00 26.94  ? 173 SER F CA  1 
ATOM   17104 C C   . SER F 1 173 ? -11.285 -6.106  41.708  1.00 25.02  ? 173 SER F C   1 
ATOM   17105 O O   . SER F 1 173 ? -11.842 -5.782  40.654  1.00 28.05  ? 173 SER F O   1 
ATOM   17106 C CB  . SER F 1 173 ? -11.378 -8.570  42.252  1.00 28.56  ? 173 SER F CB  1 
ATOM   17107 O OG  . SER F 1 173 ? -11.761 -8.457  43.622  1.00 30.16  ? 173 SER F OG  1 
ATOM   17108 N N   . ALA F 1 174 ? -11.338 -5.345  42.810  1.00 21.76  ? 174 ALA F N   1 
ATOM   17109 C CA  . ALA F 1 174 ? -11.994 -4.041  42.791  1.00 23.77  ? 174 ALA F CA  1 
ATOM   17110 C C   . ALA F 1 174 ? -11.343 -3.128  41.775  1.00 22.73  ? 174 ALA F C   1 
ATOM   17111 O O   . ALA F 1 174 ? -12.031 -2.478  40.981  1.00 24.19  ? 174 ALA F O   1 
ATOM   17112 C CB  . ALA F 1 174 ? -11.947 -3.388  44.172  1.00 21.27  ? 174 ALA F CB  1 
ATOM   17113 N N   . ILE F 1 175 ? -10.014 -3.043  41.802  1.00 21.40  ? 175 ILE F N   1 
ATOM   17114 C CA  . ILE F 1 175 ? -9.318  -2.188  40.846  1.00 26.75  ? 175 ILE F CA  1 
ATOM   17115 C C   . ILE F 1 175 ? -9.700  -2.584  39.421  1.00 23.85  ? 175 ILE F C   1 
ATOM   17116 O O   . ILE F 1 175 ? -10.091 -1.738  38.610  1.00 24.20  ? 175 ILE F O   1 
ATOM   17117 C CB  . ILE F 1 175 ? -7.796  -2.249  41.075  1.00 23.47  ? 175 ILE F CB  1 
ATOM   17118 C CG1 . ILE F 1 175 ? -7.441  -1.675  42.438  1.00 28.10  ? 175 ILE F CG1 1 
ATOM   17119 C CG2 . ILE F 1 175 ? -7.056  -1.456  40.020  1.00 22.10  ? 175 ILE F CG2 1 
ATOM   17120 C CD1 . ILE F 1 175 ? -5.948  -1.748  42.748  1.00 21.05  ? 175 ILE F CD1 1 
ATOM   17121 N N   . GLN F 1 176 ? -9.672  -3.890  39.128  1.00 26.04  ? 176 GLN F N   1 
ATOM   17122 C CA  . GLN F 1 176 ? -10.000 -4.363  37.780  1.00 31.04  ? 176 GLN F CA  1 
ATOM   17123 C C   . GLN F 1 176 ? -11.430 -4.009  37.405  1.00 31.09  ? 176 GLN F C   1 
ATOM   17124 O O   . GLN F 1 176 ? -11.683 -3.490  36.310  1.00 29.28  ? 176 GLN F O   1 
ATOM   17125 C CB  . GLN F 1 176 ? -9.806  -5.876  37.665  1.00 34.52  ? 176 GLN F CB  1 
ATOM   17126 C CG  . GLN F 1 176 ? -8.380  -6.339  37.467  1.00 34.24  ? 176 GLN F CG  1 
ATOM   17127 C CD  . GLN F 1 176 ? -8.306  -7.834  37.160  1.00 43.57  ? 176 GLN F CD  1 
ATOM   17128 O OE1 . GLN F 1 176 ? -9.205  -8.601  37.515  1.00 45.36  ? 176 GLN F OE1 1 
ATOM   17129 N NE2 . GLN F 1 176 ? -7.230  -8.250  36.507  1.00 44.70  ? 176 GLN F NE2 1 
ATOM   17130 N N   . GLU F 1 177 ? -12.377 -4.268  38.318  1.00 29.27  ? 177 GLU F N   1 
ATOM   17131 C CA  . GLU F 1 177 ? -13.787 -3.998  38.047  1.00 31.04  ? 177 GLU F CA  1 
ATOM   17132 C C   . GLU F 1 177 ? -14.094 -2.500  37.934  1.00 32.32  ? 177 GLU F C   1 
ATOM   17133 O O   . GLU F 1 177 ? -14.958 -2.102  37.139  1.00 36.31  ? 177 GLU F O   1 
ATOM   17134 C CB  . GLU F 1 177 ? -14.654 -4.631  39.138  1.00 35.26  ? 177 GLU F CB  1 
ATOM   17135 C CG  . GLU F 1 177 ? -15.880 -3.780  39.470  1.00 40.37  ? 177 GLU F CG  1 
ATOM   17136 C CD  . GLU F 1 177 ? -16.916 -4.485  40.323  1.00 53.44  ? 177 GLU F CD  1 
ATOM   17137 O OE1 . GLU F 1 177 ? -17.824 -5.161  39.759  1.00 61.31  ? 177 GLU F OE1 1 
ATOM   17138 O OE2 . GLU F 1 177 ? -16.827 -4.330  41.569  1.00 45.75  ? 177 GLU F OE2 1 
ATOM   17139 N N   . LEU F 1 178 ? -13.416 -1.652  38.709  1.00 27.90  ? 178 LEU F N   1 
ATOM   17140 C CA  . LEU F 1 178 ? -13.805 -0.247  38.784  1.00 23.44  ? 178 LEU F CA  1 
ATOM   17141 C C   . LEU F 1 178 ? -13.019 0.676   37.846  1.00 26.02  ? 178 LEU F C   1 
ATOM   17142 O O   . LEU F 1 178 ? -13.441 1.824   37.640  1.00 25.90  ? 178 LEU F O   1 
ATOM   17143 C CB  . LEU F 1 178 ? -13.665 0.253   40.224  1.00 22.69  ? 178 LEU F CB  1 
ATOM   17144 C CG  . LEU F 1 178 ? -14.581 -0.468  41.217  1.00 30.14  ? 178 LEU F CG  1 
ATOM   17145 C CD1 . LEU F 1 178 ? -14.120 -0.197  42.647  1.00 21.49  ? 178 LEU F CD1 1 
ATOM   17146 C CD2 . LEU F 1 178 ? -16.045 -0.060  41.041  1.00 27.17  ? 178 LEU F CD2 1 
ATOM   17147 N N   . ILE F 1 179 ? -11.910 0.211   37.257  1.00 22.49  ? 179 ILE F N   1 
ATOM   17148 C CA  . ILE F 1 179 ? -11.080 1.106   36.446  1.00 24.79  ? 179 ILE F CA  1 
ATOM   17149 C C   . ILE F 1 179 ? -11.625 1.315   35.045  1.00 25.28  ? 179 ILE F C   1 
ATOM   17150 O O   . ILE F 1 179 ? -11.252 2.291   34.390  1.00 24.87  ? 179 ILE F O   1 
ATOM   17151 C CB  . ILE F 1 179 ? -9.626  0.606   36.356  1.00 25.91  ? 179 ILE F CB  1 
ATOM   17152 C CG1 . ILE F 1 179 ? -8.705  1.733   35.925  1.00 21.85  ? 179 ILE F CG1 1 
ATOM   17153 C CG2 . ILE F 1 179 ? -9.497  -0.558  35.379  1.00 21.31  ? 179 ILE F CG2 1 
ATOM   17154 C CD1 . ILE F 1 179 ? -8.050  2.427   37.045  1.00 28.71  ? 179 ILE F CD1 1 
ATOM   17155 N N   . ALA F 1 180 ? -12.540 0.466   34.576  1.00 28.40  ? 180 ALA F N   1 
ATOM   17156 C CA  . ALA F 1 180 ? -12.932 0.528   33.166  1.00 33.00  ? 180 ALA F CA  1 
ATOM   17157 C C   . ALA F 1 180 ? -13.740 1.786   32.840  1.00 32.27  ? 180 ALA F C   1 
ATOM   17158 O O   . ALA F 1 180 ? -13.572 2.373   31.766  1.00 31.35  ? 180 ALA F O   1 
ATOM   17159 C CB  . ALA F 1 180 ? -13.726 -0.725  32.793  1.00 31.35  ? 180 ALA F CB  1 
ATOM   17160 N N   . GLU F 1 181 ? -14.608 2.225   33.754  1.00 33.48  ? 181 GLU F N   1 
ATOM   17161 C CA  . GLU F 1 181 ? -15.590 3.259   33.415  1.00 32.11  ? 181 GLU F CA  1 
ATOM   17162 C C   . GLU F 1 181 ? -14.935 4.595   33.055  1.00 29.63  ? 181 GLU F C   1 
ATOM   17163 O O   . GLU F 1 181 ? -15.354 5.251   32.095  1.00 33.07  ? 181 GLU F O   1 
ATOM   17164 C CB  . GLU F 1 181 ? -16.578 3.433   34.568  1.00 30.79  ? 181 GLU F CB  1 
ATOM   17165 C CG  . GLU F 1 181 ? -17.739 4.378   34.270  1.00 31.47  ? 181 GLU F CG  1 
ATOM   17166 C CD  . GLU F 1 181 ? -18.481 4.808   35.539  1.00 35.90  ? 181 GLU F CD  1 
ATOM   17167 O OE1 . GLU F 1 181 ? -18.254 4.195   36.608  1.00 41.20  ? 181 GLU F OE1 1 
ATOM   17168 O OE2 . GLU F 1 181 ? -19.291 5.758   35.476  1.00 41.79  ? 181 GLU F OE2 1 
ATOM   17169 N N   . THR F 1 182 ? -13.923 5.031   33.826  1.00 29.82  ? 182 THR F N   1 
ATOM   17170 C CA  . THR F 1 182 ? -13.228 6.296   33.588  1.00 20.79  ? 182 THR F CA  1 
ATOM   17171 C C   . THR F 1 182 ? -11.727 6.155   33.362  1.00 22.64  ? 182 THR F C   1 
ATOM   17172 O O   . THR F 1 182 ? -11.078 7.143   33.010  1.00 24.36  ? 182 THR F O   1 
ATOM   17173 C CB  . THR F 1 182 ? -13.437 7.261   34.767  1.00 26.01  ? 182 THR F CB  1 
ATOM   17174 O OG1 . THR F 1 182 ? -12.717 6.788   35.925  1.00 22.06  ? 182 THR F OG1 1 
ATOM   17175 C CG2 . THR F 1 182 ? -14.928 7.394   35.112  1.00 25.50  ? 182 THR F CG2 1 
ATOM   17176 N N   . GLY F 1 183 ? -11.155 4.978   33.555  1.00 22.12  ? 183 GLY F N   1 
ATOM   17177 C CA  . GLY F 1 183 ? -9.720  4.855   33.580  1.00 22.35  ? 183 GLY F CA  1 
ATOM   17178 C C   . GLY F 1 183 ? -9.070  5.325   34.860  1.00 27.80  ? 183 GLY F C   1 
ATOM   17179 O O   . GLY F 1 183 ? -7.843  5.472   34.890  1.00 23.92  ? 183 GLY F O   1 
ATOM   17180 N N   . MET F 1 184 ? -9.851  5.569   35.920  1.00 27.64  ? 184 MET F N   1 
ATOM   17181 C CA  . MET F 1 184 ? -9.325  6.101   37.175  1.00 26.80  ? 184 MET F CA  1 
ATOM   17182 C C   . MET F 1 184 ? -10.019 5.456   38.367  1.00 22.49  ? 184 MET F C   1 
ATOM   17183 O O   . MET F 1 184 ? -11.244 5.324   38.398  1.00 22.08  ? 184 MET F O   1 
ATOM   17184 C CB  . MET F 1 184 ? -9.491  7.619   37.252  1.00 23.09  ? 184 MET F CB  1 
ATOM   17185 C CG  . MET F 1 184 ? -9.092  8.357   35.988  1.00 28.16  ? 184 MET F CG  1 
ATOM   17186 S SD  . MET F 1 184 ? -9.048  10.138  36.250  1.00 25.82  ? 184 MET F SD  1 
ATOM   17187 C CE  . MET F 1 184 ? -10.759 10.528  35.862  1.00 29.34  ? 184 MET F CE  1 
ATOM   17188 N N   . VAL F 1 185 ? -9.226  5.088   39.353  1.00 20.82  ? 185 VAL F N   1 
ATOM   17189 C CA  . VAL F 1 185 ? -9.708  4.531   40.600  1.00 21.57  ? 185 VAL F CA  1 
ATOM   17190 C C   . VAL F 1 185 ? -8.924  5.211   41.710  1.00 23.33  ? 185 VAL F C   1 
ATOM   17191 O O   . VAL F 1 185 ? -7.768  5.605   41.522  1.00 25.60  ? 185 VAL F O   1 
ATOM   17192 C CB  . VAL F 1 185 ? -9.541  2.997   40.632  1.00 23.01  ? 185 VAL F CB  1 
ATOM   17193 C CG1 . VAL F 1 185 ? -9.715  2.461   42.037  1.00 27.86  ? 185 VAL F CG1 1 
ATOM   17194 C CG2 . VAL F 1 185 ? -10.554 2.338   39.714  1.00 24.32  ? 185 VAL F CG2 1 
ATOM   17195 N N   . ILE F 1 186 ? -9.563  5.378   42.863  1.00 21.08  ? 186 ILE F N   1 
ATOM   17196 C CA  . ILE F 1 186 ? -8.925  5.946   44.042  1.00 19.00  ? 186 ILE F CA  1 
ATOM   17197 C C   . ILE F 1 186 ? -9.036  4.937   45.174  1.00 22.24  ? 186 ILE F C   1 
ATOM   17198 O O   . ILE F 1 186 ? -10.107 4.367   45.395  1.00 25.26  ? 186 ILE F O   1 
ATOM   17199 C CB  . ILE F 1 186 ? -9.563  7.286   44.429  1.00 21.53  ? 186 ILE F CB  1 
ATOM   17200 C CG1 . ILE F 1 186 ? -8.828  7.897   45.623  1.00 24.71  ? 186 ILE F CG1 1 
ATOM   17201 C CG2 . ILE F 1 186 ? -11.065 7.131   44.686  1.00 20.50  ? 186 ILE F CG2 1 
ATOM   17202 C CD1 . ILE F 1 186 ? -8.935  9.449   45.643  1.00 24.70  ? 186 ILE F CD1 1 
ATOM   17203 N N   . ALA F 1 187 ? -7.926  4.687   45.861  1.00 17.53  ? 187 ALA F N   1 
ATOM   17204 C CA  . ALA F 1 187 ? -7.895  3.816   47.016  1.00 19.36  ? 187 ALA F CA  1 
ATOM   17205 C C   . ALA F 1 187 ? -7.657  4.671   48.255  1.00 23.87  ? 187 ALA F C   1 
ATOM   17206 O O   . ALA F 1 187 ? -6.824  5.578   48.230  1.00 23.37  ? 187 ALA F O   1 
ATOM   17207 C CB  . ALA F 1 187 ? -6.809  2.750   46.869  1.00 22.56  ? 187 ALA F CB  1 
ATOM   17208 N N   . LYS F 1 188 ? -8.399  4.396   49.337  1.00 21.46  ? 188 LYS F N   1 
ATOM   17209 C CA  . LYS F 1 188 ? -8.448  5.301   50.480  1.00 22.59  ? 188 LYS F CA  1 
ATOM   17210 C C   . LYS F 1 188 ? -8.282  4.553   51.797  1.00 22.36  ? 188 LYS F C   1 
ATOM   17211 O O   . LYS F 1 188 ? -8.918  3.516   52.010  1.00 18.12  ? 188 LYS F O   1 
ATOM   17212 C CB  . LYS F 1 188 ? -9.766  6.068   50.507  1.00 22.05  ? 188 LYS F CB  1 
ATOM   17213 C CG  . LYS F 1 188 ? -9.999  6.984   49.305  1.00 21.87  ? 188 LYS F CG  1 
ATOM   17214 C CD  . LYS F 1 188 ? -11.507 7.143   49.043  1.00 28.40  ? 188 LYS F CD  1 
ATOM   17215 C CE  . LYS F 1 188 ? -11.889 8.580   48.694  1.00 34.59  ? 188 LYS F CE  1 
ATOM   17216 N NZ  . LYS F 1 188 ? -13.355 8.874   48.970  1.00 31.84  ? 188 LYS F NZ  1 
ATOM   17217 N N   . GLN F 1 189 ? -7.419  5.080   52.673  1.00 26.22  ? 189 GLN F N   1 
ATOM   17218 C CA  . GLN F 1 189 ? -7.399  4.671   54.075  1.00 30.00  ? 189 GLN F CA  1 
ATOM   17219 C C   . GLN F 1 189 ? -8.807  4.730   54.655  1.00 28.40  ? 189 GLN F C   1 
ATOM   17220 O O   . GLN F 1 189 ? -9.583  5.633   54.331  1.00 30.37  ? 189 GLN F O   1 
ATOM   17221 C CB  . GLN F 1 189 ? -6.488  5.606   54.864  1.00 32.80  ? 189 GLN F CB  1 
ATOM   17222 C CG  . GLN F 1 189 ? -5.225  4.983   55.417  1.00 42.55  ? 189 GLN F CG  1 
ATOM   17223 C CD  . GLN F 1 189 ? -4.226  6.044   55.886  1.00 43.33  ? 189 GLN F CD  1 
ATOM   17224 O OE1 . GLN F 1 189 ? -4.619  7.120   56.355  1.00 40.39  ? 189 GLN F OE1 1 
ATOM   17225 N NE2 . GLN F 1 189 ? -2.927  5.748   55.739  1.00 46.77  ? 189 GLN F NE2 1 
ATOM   17226 N N   . ASP F 1 190 ? -9.141  3.779   55.531  1.00 24.70  ? 190 ASP F N   1 
ATOM   17227 C CA  . ASP F 1 190 ? -10.501 3.780   56.073  1.00 28.21  ? 190 ASP F CA  1 
ATOM   17228 C C   . ASP F 1 190 ? -10.747 4.936   57.049  1.00 31.70  ? 190 ASP F C   1 
ATOM   17229 O O   . ASP F 1 190 ? -11.828 5.538   57.037  1.00 30.95  ? 190 ASP F O   1 
ATOM   17230 C CB  . ASP F 1 190 ? -10.824 2.456   56.748  1.00 27.89  ? 190 ASP F CB  1 
ATOM   17231 C CG  . ASP F 1 190 ? -12.317 2.203   56.799  1.00 28.04  ? 190 ASP F CG  1 
ATOM   17232 O OD1 . ASP F 1 190 ? -13.048 2.850   56.018  1.00 28.30  ? 190 ASP F OD1 1 
ATOM   17233 O OD2 . ASP F 1 190 ? -12.769 1.378   57.612  1.00 31.05  ? 190 ASP F OD2 1 
ATOM   17234 N N   . ARG F 1 191 ? -9.792  5.257   57.920  1.00 32.24  ? 191 ARG F N   1 
ATOM   17235 C CA  . ARG F 1 191 ? -10.103 6.250   58.941  1.00 38.37  ? 191 ARG F CA  1 
ATOM   17236 C C   . ARG F 1 191 ? -9.696  7.645   58.502  1.00 45.28  ? 191 ARG F C   1 
ATOM   17237 O O   . ARG F 1 191 ? -8.722  7.825   57.765  1.00 51.68  ? 191 ARG F O   1 
ATOM   17238 C CB  . ARG F 1 191 ? -9.465  5.886   60.280  1.00 37.28  ? 191 ARG F CB  1 
ATOM   17239 C CG  . ARG F 1 191 ? -10.191 4.680   60.827  1.00 42.23  ? 191 ARG F CG  1 
ATOM   17240 C CD  . ARG F 1 191 ? -10.546 4.621   62.315  1.00 42.36  ? 191 ARG F CD  1 
ATOM   17241 N NE  . ARG F 1 191 ? -10.988 3.252   62.575  1.00 42.56  ? 191 ARG F NE  1 
ATOM   17242 C CZ  . ARG F 1 191 ? -11.397 2.759   63.735  1.00 42.38  ? 191 ARG F CZ  1 
ATOM   17243 N NH1 . ARG F 1 191 ? -11.440 3.499   64.832  1.00 47.48  ? 191 ARG F NH1 1 
ATOM   17244 N NH2 . ARG F 1 191 ? -11.767 1.483   63.796  1.00 42.39  ? 191 ARG F NH2 1 
ATOM   17245 N N   . SER F 1 192 ? -10.471 8.632   58.970  1.00 48.55  ? 192 SER F N   1 
ATOM   17246 C CA  . SER F 1 192 ? -10.438 9.983   58.417  1.00 52.02  ? 192 SER F CA  1 
ATOM   17247 C C   . SER F 1 192 ? -9.026  10.546  58.406  1.00 54.39  ? 192 SER F C   1 
ATOM   17248 O O   . SER F 1 192 ? -8.281  10.431  59.385  1.00 54.19  ? 192 SER F O   1 
ATOM   17249 C CB  . SER F 1 192 ? -11.367 10.918  59.203  1.00 49.11  ? 192 SER F CB  1 
ATOM   17250 O OG  . SER F 1 192 ? -11.617 10.455  60.522  1.00 50.85  ? 192 SER F OG  1 
ATOM   17251 N N   . GLY F 1 193 ? -8.664  11.141  57.275  1.00 57.94  ? 193 GLY F N   1 
ATOM   17252 C CA  . GLY F 1 193 ? -7.353  11.732  57.090  1.00 62.40  ? 193 GLY F CA  1 
ATOM   17253 C C   . GLY F 1 193 ? -7.451  12.758  55.988  1.00 64.37  ? 193 GLY F C   1 
ATOM   17254 O O   . GLY F 1 193 ? -8.420  12.790  55.224  1.00 64.23  ? 193 GLY F O   1 
ATOM   17255 N N   . GLY F 1 194 ? -6.427  13.602  55.911  1.00 58.19  ? 194 GLY F N   1 
ATOM   17256 C CA  . GLY F 1 194 ? -6.492  14.731  55.007  1.00 66.52  ? 194 GLY F CA  1 
ATOM   17257 C C   . GLY F 1 194 ? -5.872  14.503  53.645  1.00 64.41  ? 194 GLY F C   1 
ATOM   17258 O O   . GLY F 1 194 ? -4.747  14.956  53.397  1.00 63.35  ? 194 GLY F O   1 
ATOM   17259 N N   . GLY F 1 195 ? -6.583  13.795  52.758  1.00 60.75  ? 195 GLY F N   1 
ATOM   17260 C CA  . GLY F 1 195 ? -6.152  13.607  51.380  1.00 49.97  ? 195 GLY F CA  1 
ATOM   17261 C C   . GLY F 1 195 ? -4.893  12.774  51.235  1.00 51.40  ? 195 GLY F C   1 
ATOM   17262 O O   . GLY F 1 195 ? -4.625  12.211  50.166  1.00 45.15  ? 195 GLY F O   1 
ATOM   17263 N N   . HIS F 1 196 ? -4.121  12.683  52.323  1.00 55.82  ? 196 HIS F N   1 
ATOM   17264 C CA  . HIS F 1 196 ? -2.825  12.022  52.360  1.00 49.02  ? 196 HIS F CA  1 
ATOM   17265 C C   . HIS F 1 196 ? -2.930  10.515  52.536  1.00 44.99  ? 196 HIS F C   1 
ATOM   17266 O O   . HIS F 1 196 ? -1.930  9.812   52.356  1.00 46.92  ? 196 HIS F O   1 
ATOM   17267 C CB  . HIS F 1 196 ? -1.979  12.613  53.493  1.00 57.17  ? 196 HIS F CB  1 
ATOM   17268 C CG  . HIS F 1 196 ? -0.526  12.742  53.155  1.00 64.66  ? 196 HIS F CG  1 
ATOM   17269 N ND1 . HIS F 1 196 ? 0.003   13.872  52.569  1.00 63.86  ? 196 HIS F ND1 1 
ATOM   17270 C CD2 . HIS F 1 196 ? 0.507   11.879  53.308  1.00 66.29  ? 196 HIS F CD2 1 
ATOM   17271 C CE1 . HIS F 1 196 ? 1.300   13.702  52.382  1.00 69.46  ? 196 HIS F CE1 1 
ATOM   17272 N NE2 . HIS F 1 196 ? 1.632   12.502  52.822  1.00 66.32  ? 196 HIS F NE2 1 
ATOM   17273 N N   . GLY F 1 197 ? -4.097  10.005  52.894  1.00 45.30  ? 197 GLY F N   1 
ATOM   17274 C CA  . GLY F 1 197 ? -4.275  8.573   52.958  1.00 39.71  ? 197 GLY F CA  1 
ATOM   17275 C C   . GLY F 1 197 ? -4.973  8.027   51.731  1.00 32.21  ? 197 GLY F C   1 
ATOM   17276 O O   . GLY F 1 197 ? -5.573  6.953   51.793  1.00 32.00  ? 197 GLY F O   1 
ATOM   17277 N N   . ASN F 1 198 ? -4.912  8.754   50.619  1.00 32.92  ? 198 ASN F N   1 
ATOM   17278 C CA  . ASN F 1 198 ? -5.628  8.400   49.399  1.00 29.96  ? 198 ASN F CA  1 
ATOM   17279 C C   . ASN F 1 198 ? -4.641  8.255   48.244  1.00 28.18  ? 198 ASN F C   1 
ATOM   17280 O O   . ASN F 1 198 ? -3.719  9.059   48.094  1.00 22.94  ? 198 ASN F O   1 
ATOM   17281 C CB  . ASN F 1 198 ? -6.689  9.457   49.045  1.00 27.28  ? 198 ASN F CB  1 
ATOM   17282 C CG  . ASN F 1 198 ? -7.756  9.626   50.129  1.00 34.90  ? 198 ASN F CG  1 
ATOM   17283 O OD1 . ASN F 1 198 ? -7.886  8.803   51.041  1.00 32.08  ? 198 ASN F OD1 1 
ATOM   17284 N ND2 . ASN F 1 198 ? -8.526  10.704  50.026  1.00 32.80  ? 198 ASN F ND2 1 
ATOM   17285 N N   . ILE F 1 199 ? -4.839  7.237   47.410  1.00 25.48  ? 199 ILE F N   1 
ATOM   17286 C CA  . ILE F 1 199 ? -3.929  6.983   46.310  1.00 23.35  ? 199 ILE F CA  1 
ATOM   17287 C C   . ILE F 1 199 ? -4.757  6.802   45.052  1.00 19.63  ? 199 ILE F C   1 
ATOM   17288 O O   . ILE F 1 199 ? -5.698  6.006   45.035  1.00 16.27  ? 199 ILE F O   1 
ATOM   17289 C CB  . ILE F 1 199 ? -3.031  5.770   46.594  1.00 22.10  ? 199 ILE F CB  1 
ATOM   17290 C CG1 . ILE F 1 199 ? -2.276  5.989   47.910  1.00 22.04  ? 199 ILE F CG1 1 
ATOM   17291 C CG2 . ILE F 1 199 ? -2.066  5.538   45.445  1.00 24.90  ? 199 ILE F CG2 1 
ATOM   17292 C CD1 . ILE F 1 199 ? -1.167  4.973   48.181  1.00 23.01  ? 199 ILE F CD1 1 
ATOM   17293 N N   . GLY F 1 200 ? -4.442  7.579   44.014  1.00 23.89  ? 200 GLY F N   1 
ATOM   17294 C CA  . GLY F 1 200 ? -5.103  7.431   42.733  1.00 23.47  ? 200 GLY F CA  1 
ATOM   17295 C C   . GLY F 1 200 ? -4.398  6.388   41.878  1.00 25.47  ? 200 GLY F C   1 
ATOM   17296 O O   . GLY F 1 200 ? -3.191  6.181   41.988  1.00 22.61  ? 200 GLY F O   1 
ATOM   17297 N N   . ILE F 1 201 ? -5.180  5.700   41.048  1.00 25.27  ? 201 ILE F N   1 
ATOM   17298 C CA  . ILE F 1 201 ? -4.672  4.689   40.124  1.00 23.17  ? 201 ILE F CA  1 
ATOM   17299 C C   . ILE F 1 201 ? -5.286  4.971   38.761  1.00 27.94  ? 201 ILE F C   1 
ATOM   17300 O O   . ILE F 1 201 ? -6.513  5.093   38.637  1.00 24.85  ? 201 ILE F O   1 
ATOM   17301 C CB  . ILE F 1 201 ? -4.999  3.255   40.588  1.00 22.78  ? 201 ILE F CB  1 
ATOM   17302 C CG1 . ILE F 1 201 ? -4.273  2.941   41.898  1.00 25.38  ? 201 ILE F CG1 1 
ATOM   17303 C CG2 . ILE F 1 201 ? -4.568  2.241   39.550  1.00 26.28  ? 201 ILE F CG2 1 
ATOM   17304 C CD1 . ILE F 1 201 ? -5.188  2.339   42.934  1.00 24.04  ? 201 ILE F CD1 1 
ATOM   17305 N N   . SER F 1 202 ? -4.433  5.093   37.744  1.00 24.68  ? 202 SER F N   1 
ATOM   17306 C CA  . SER F 1 202 ? -4.851  5.543   36.426  1.00 28.11  ? 202 SER F CA  1 
ATOM   17307 C C   . SER F 1 202 ? -4.240  4.704   35.319  1.00 29.50  ? 202 SER F C   1 
ATOM   17308 O O   . SER F 1 202 ? -3.051  4.365   35.364  1.00 20.90  ? 202 SER F O   1 
ATOM   17309 C CB  . SER F 1 202 ? -4.458  6.997   36.180  1.00 26.47  ? 202 SER F CB  1 
ATOM   17310 O OG  . SER F 1 202 ? -5.587  7.796   36.421  1.00 35.51  ? 202 SER F OG  1 
ATOM   17311 N N   . THR F 1 203 ? -5.052  4.423   34.298  1.00 25.47  ? 203 THR F N   1 
ATOM   17312 C CA  . THR F 1 203 ? -4.482  3.879   33.069  1.00 28.40  ? 203 THR F CA  1 
ATOM   17313 C C   . THR F 1 203 ? -3.629  4.927   32.363  1.00 31.08  ? 203 THR F C   1 
ATOM   17314 O O   . THR F 1 203 ? -2.544  4.615   31.857  1.00 26.58  ? 203 THR F O   1 
ATOM   17315 C CB  . THR F 1 203 ? -5.592  3.376   32.140  1.00 26.15  ? 203 THR F CB  1 
ATOM   17316 O OG1 . THR F 1 203 ? -6.515  4.441   31.875  1.00 28.41  ? 203 THR F OG1 1 
ATOM   17317 C CG2 . THR F 1 203 ? -6.347  2.246   32.789  1.00 26.64  ? 203 THR F CG2 1 
ATOM   17318 N N   . SER F 1 204 ? -4.094  6.192   32.343  1.00 30.20  ? 204 SER F N   1 
ATOM   17319 C CA  . SER F 1 204 ? -3.432  7.230   31.559  1.00 29.59  ? 204 SER F CA  1 
ATOM   17320 C C   . SER F 1 204 ? -2.587  8.127   32.448  1.00 31.08  ? 204 SER F C   1 
ATOM   17321 O O   . SER F 1 204 ? -3.060  8.562   33.504  1.00 28.86  ? 204 SER F O   1 
ATOM   17322 C CB  . SER F 1 204 ? -4.464  8.077   30.827  1.00 28.94  ? 204 SER F CB  1 
ATOM   17323 O OG  . SER F 1 204 ? -3.873  9.271   30.354  1.00 33.94  ? 204 SER F OG  1 
ATOM   17324 N N   . PRO F 1 205 ? -1.352  8.462   32.063  1.00 35.17  ? 205 PRO F N   1 
ATOM   17325 C CA  . PRO F 1 205 ? -0.564  9.401   32.883  1.00 34.66  ? 205 PRO F CA  1 
ATOM   17326 C C   . PRO F 1 205 ? -1.111  10.818  32.881  1.00 32.46  ? 205 PRO F C   1 
ATOM   17327 O O   . PRO F 1 205 ? -0.683  11.628  33.712  1.00 35.43  ? 205 PRO F O   1 
ATOM   17328 C CB  . PRO F 1 205 ? 0.834   9.343   32.250  1.00 36.53  ? 205 PRO F CB  1 
ATOM   17329 C CG  . PRO F 1 205 ? 0.616   8.865   30.845  1.00 36.60  ? 205 PRO F CG  1 
ATOM   17330 C CD  . PRO F 1 205 ? -0.625  8.001   30.861  1.00 28.81  ? 205 PRO F CD  1 
ATOM   17331 N N   . GLU F 1 206 ? -2.034  11.148  31.981  1.00 33.17  ? 206 GLU F N   1 
ATOM   17332 C CA  . GLU F 1 206 ? -2.623  12.479  31.938  1.00 38.96  ? 206 GLU F CA  1 
ATOM   17333 C C   . GLU F 1 206 ? -3.738  12.656  32.965  1.00 35.73  ? 206 GLU F C   1 
ATOM   17334 O O   . GLU F 1 206 ? -4.287  13.757  33.099  1.00 31.71  ? 206 GLU F O   1 
ATOM   17335 C CB  . GLU F 1 206 ? -3.151  12.759  30.526  1.00 40.26  ? 206 GLU F CB  1 
ATOM   17336 C CG  . GLU F 1 206 ? -2.063  12.707  29.450  1.00 44.97  ? 206 GLU F CG  1 
ATOM   17337 C CD  . GLU F 1 206 ? -2.322  13.661  28.292  1.00 56.71  ? 206 GLU F CD  1 
ATOM   17338 O OE1 . GLU F 1 206 ? -2.958  14.713  28.511  1.00 61.86  ? 206 GLU F OE1 1 
ATOM   17339 O OE2 . GLU F 1 206 ? -1.902  13.347  27.153  1.00 55.61  ? 206 GLU F OE2 1 
ATOM   17340 N N   . SER F 1 207 ? -4.083  11.604  33.689  1.00 27.65  ? 207 SER F N   1 
ATOM   17341 C CA  . SER F 1 207 ? -5.155  11.693  34.662  1.00 34.06  ? 207 SER F CA  1 
ATOM   17342 C C   . SER F 1 207 ? -4.621  12.305  35.949  1.00 35.82  ? 207 SER F C   1 
ATOM   17343 O O   . SER F 1 207 ? -3.547  11.922  36.430  1.00 30.84  ? 207 SER F O   1 
ATOM   17344 C CB  . SER F 1 207 ? -5.727  10.311  34.921  1.00 29.67  ? 207 SER F CB  1 
ATOM   17345 O OG  . SER F 1 207 ? -6.744  10.020  33.979  1.00 30.02  ? 207 SER F OG  1 
ATOM   17346 N N   . SER F 1 208 ? -5.350  13.273  36.493  1.00 33.40  ? 208 SER F N   1 
ATOM   17347 C CA  . SER F 1 208 ? -4.919  13.966  37.702  1.00 35.12  ? 208 SER F CA  1 
ATOM   17348 C C   . SER F 1 208 ? -5.948  13.767  38.808  1.00 35.69  ? 208 SER F C   1 
ATOM   17349 O O   . SER F 1 208 ? -7.145  13.625  38.538  1.00 32.68  ? 208 SER F O   1 
ATOM   17350 C CB  . SER F 1 208 ? -4.671  15.457  37.421  1.00 38.52  ? 208 SER F CB  1 
ATOM   17351 O OG  . SER F 1 208 ? -5.884  16.168  37.268  1.00 42.69  ? 208 SER F OG  1 
ATOM   17352 N N   . PHE F 1 209 ? -5.461  13.699  40.054  1.00 28.91  ? 209 PHE F N   1 
ATOM   17353 C CA  . PHE F 1 209 ? -6.293  13.418  41.229  1.00 32.88  ? 209 PHE F CA  1 
ATOM   17354 C C   . PHE F 1 209 ? -6.045  14.454  42.320  1.00 37.20  ? 209 PHE F C   1 
ATOM   17355 O O   . PHE F 1 209 ? -5.150  14.280  43.160  1.00 36.53  ? 209 PHE F O   1 
ATOM   17356 C CB  . PHE F 1 209 ? -6.014  12.036  41.798  1.00 30.62  ? 209 PHE F CB  1 
ATOM   17357 C CG  . PHE F 1 209 ? -6.305  10.908  40.870  1.00 31.72  ? 209 PHE F CG  1 
ATOM   17358 C CD1 . PHE F 1 209 ? -5.401  10.552  39.880  1.00 27.60  ? 209 PHE F CD1 1 
ATOM   17359 C CD2 . PHE F 1 209 ? -7.457  10.167  41.019  1.00 26.93  ? 209 PHE F CD2 1 
ATOM   17360 C CE1 . PHE F 1 209 ? -5.659  9.479   39.045  1.00 31.89  ? 209 PHE F CE1 1 
ATOM   17361 C CE2 . PHE F 1 209 ? -7.718  9.103   40.182  1.00 27.90  ? 209 PHE F CE2 1 
ATOM   17362 C CZ  . PHE F 1 209 ? -6.814  8.760   39.198  1.00 27.63  ? 209 PHE F CZ  1 
ATOM   17363 N N   . PRO F 1 210 ? -6.823  15.533  42.349  1.00 33.99  ? 210 PRO F N   1 
ATOM   17364 C CA  . PRO F 1 210 ? -6.606  16.588  43.349  1.00 38.31  ? 210 PRO F CA  1 
ATOM   17365 C C   . PRO F 1 210 ? -6.490  16.068  44.782  1.00 39.18  ? 210 PRO F C   1 
ATOM   17366 O O   . PRO F 1 210 ? -7.354  15.340  45.272  1.00 31.79  ? 210 PRO F O   1 
ATOM   17367 C CB  . PRO F 1 210 ? -7.840  17.478  43.175  1.00 38.77  ? 210 PRO F CB  1 
ATOM   17368 C CG  . PRO F 1 210 ? -8.274  17.276  41.741  1.00 39.31  ? 210 PRO F CG  1 
ATOM   17369 C CD  . PRO F 1 210 ? -7.629  16.012  41.213  1.00 36.37  ? 210 PRO F CD  1 
ATOM   17370 N N   . GLY F 1 211 ? -5.399  16.456  45.457  1.00 40.80  ? 211 GLY F N   1 
ATOM   17371 C CA  . GLY F 1 211 ? -5.234  16.254  46.889  1.00 36.40  ? 211 GLY F CA  1 
ATOM   17372 C C   . GLY F 1 211 ? -4.854  14.855  47.343  1.00 41.72  ? 211 GLY F C   1 
ATOM   17373 O O   . GLY F 1 211 ? -4.681  14.644  48.549  1.00 46.74  ? 211 GLY F O   1 
ATOM   17374 N N   . THR F 1 212 ? -4.720  13.892  46.437  1.00 37.59  ? 212 THR F N   1 
ATOM   17375 C CA  . THR F 1 212 ? -4.286  12.565  46.840  1.00 37.44  ? 212 THR F CA  1 
ATOM   17376 C C   . THR F 1 212 ? -2.804  12.560  47.234  1.00 33.81  ? 212 THR F C   1 
ATOM   17377 O O   . THR F 1 212 ? -2.047  13.493  46.946  1.00 32.66  ? 212 THR F O   1 
ATOM   17378 C CB  . THR F 1 212 ? -4.566  11.567  45.716  1.00 33.00  ? 212 THR F CB  1 
ATOM   17379 O OG1 . THR F 1 212 ? -3.772  11.899  44.572  1.00 31.43  ? 212 THR F OG1 1 
ATOM   17380 C CG2 . THR F 1 212 ? -6.033  11.622  45.328  1.00 38.19  ? 212 THR F CG2 1 
ATOM   17381 N N   . ARG F 1 213 ? -2.409  11.491  47.932  1.00 34.56  ? 213 ARG F N   1 
ATOM   17382 C CA  . ARG F 1 213 ? -1.006  11.290  48.291  1.00 34.84  ? 213 ARG F CA  1 
ATOM   17383 C C   . ARG F 1 213 ? -0.151  11.127  47.050  1.00 36.80  ? 213 ARG F C   1 
ATOM   17384 O O   . ARG F 1 213 ? 0.901   11.757  46.916  1.00 34.30  ? 213 ARG F O   1 
ATOM   17385 C CB  . ARG F 1 213 ? -0.856  10.056  49.180  1.00 40.70  ? 213 ARG F CB  1 
ATOM   17386 C CG  . ARG F 1 213 ? 0.592   9.671   49.448  1.00 43.55  ? 213 ARG F CG  1 
ATOM   17387 C CD  . ARG F 1 213 ? 0.746   8.834   50.723  1.00 44.44  ? 213 ARG F CD  1 
ATOM   17388 N NE  . ARG F 1 213 ? 1.185   7.476   50.420  1.00 47.78  ? 213 ARG F NE  1 
ATOM   17389 C CZ  . ARG F 1 213 ? 0.763   6.390   51.048  1.00 36.94  ? 213 ARG F CZ  1 
ATOM   17390 N NH1 . ARG F 1 213 ? -0.067  6.463   52.067  1.00 42.26  ? 213 ARG F NH1 1 
ATOM   17391 N NH2 . ARG F 1 213 ? 1.169   5.200   50.625  1.00 45.46  ? 213 ARG F NH2 1 
ATOM   17392 N N   . GLU F 1 214 ? -0.571  10.258  46.144  1.00 35.25  ? 214 GLU F N   1 
ATOM   17393 C CA  . GLU F 1 214 ? 0.114   10.146  44.869  1.00 37.76  ? 214 GLU F CA  1 
ATOM   17394 C C   . GLU F 1 214 ? -0.808  9.451   43.883  1.00 33.01  ? 214 GLU F C   1 
ATOM   17395 O O   . GLU F 1 214 ? -1.966  9.147   44.185  1.00 31.25  ? 214 GLU F O   1 
ATOM   17396 C CB  . GLU F 1 214 ? 1.456   9.418   45.000  1.00 42.62  ? 214 GLU F CB  1 
ATOM   17397 C CG  . GLU F 1 214 ? 1.539   8.257   45.980  1.00 39.28  ? 214 GLU F CG  1 
ATOM   17398 C CD  . GLU F 1 214 ? 2.965   8.101   46.501  1.00 48.78  ? 214 GLU F CD  1 
ATOM   17399 O OE1 . GLU F 1 214 ? 3.811   8.959   46.141  1.00 40.94  ? 214 GLU F OE1 1 
ATOM   17400 O OE2 . GLU F 1 214 ? 3.244   7.130   47.246  1.00 47.21  ? 214 GLU F OE2 1 
ATOM   17401 N N   . VAL F 1 215 ? -0.266  9.216   42.691  1.00 28.82  ? 215 VAL F N   1 
ATOM   17402 C CA  . VAL F 1 215 ? -0.974  8.673   41.543  1.00 29.62  ? 215 VAL F CA  1 
ATOM   17403 C C   . VAL F 1 215 ? -0.118  7.563   40.952  1.00 29.78  ? 215 VAL F C   1 
ATOM   17404 O O   . VAL F 1 215 ? 1.016   7.817   40.526  1.00 31.50  ? 215 VAL F O   1 
ATOM   17405 C CB  . VAL F 1 215 ? -1.238  9.756   40.491  1.00 26.93  ? 215 VAL F CB  1 
ATOM   17406 C CG1 . VAL F 1 215 ? -1.727  9.113   39.192  1.00 24.99  ? 215 VAL F CG1 1 
ATOM   17407 C CG2 . VAL F 1 215 ? -2.216  10.767  41.044  1.00 31.36  ? 215 VAL F CG2 1 
ATOM   17408 N N   . LEU F 1 216 ? -0.648  6.342   40.928  1.00 26.24  ? 216 LEU F N   1 
ATOM   17409 C CA  . LEU F 1 216 ? 0.069   5.198   40.378  1.00 28.36  ? 216 LEU F CA  1 
ATOM   17410 C C   . LEU F 1 216 ? -0.537  4.775   39.041  1.00 29.85  ? 216 LEU F C   1 
ATOM   17411 O O   . LEU F 1 216 ? -1.682  5.098   38.711  1.00 30.47  ? 216 LEU F O   1 
ATOM   17412 C CB  . LEU F 1 216 ? 0.073   4.018   41.358  1.00 23.83  ? 216 LEU F CB  1 
ATOM   17413 C CG  . LEU F 1 216 ? 0.319   4.338   42.842  1.00 26.55  ? 216 LEU F CG  1 
ATOM   17414 C CD1 . LEU F 1 216 ? 0.543   3.081   43.693  1.00 21.55  ? 216 LEU F CD1 1 
ATOM   17415 C CD2 . LEU F 1 216 ? 1.498   5.257   42.994  1.00 30.03  ? 216 LEU F CD2 1 
ATOM   17416 N N   . ALA F 1 217 ? 0.248   4.042   38.270  1.00 26.34  ? 217 ALA F N   1 
ATOM   17417 C CA  . ALA F 1 217 ? -0.192  3.559   36.974  1.00 23.17  ? 217 ALA F CA  1 
ATOM   17418 C C   . ALA F 1 217 ? -0.767  2.167   37.119  1.00 28.25  ? 217 ALA F C   1 
ATOM   17419 O O   . ALA F 1 217 ? -0.221  1.328   37.842  1.00 26.97  ? 217 ALA F O   1 
ATOM   17420 C CB  . ALA F 1 217 ? 0.966   3.523   35.975  1.00 27.36  ? 217 ALA F CB  1 
ATOM   17421 N N   . TYR F 1 218 ? -1.877  1.925   36.428  1.00 24.24  ? 218 TYR F N   1 
ATOM   17422 C CA  . TYR F 1 218 ? -2.406  0.578   36.342  1.00 27.55  ? 218 TYR F CA  1 
ATOM   17423 C C   . TYR F 1 218 ? -1.665  -0.219  35.271  1.00 27.58  ? 218 TYR F C   1 
ATOM   17424 O O   . TYR F 1 218 ? -1.413  0.268   34.163  1.00 27.95  ? 218 TYR F O   1 
ATOM   17425 C CB  . TYR F 1 218 ? -3.898  0.597   36.033  1.00 25.55  ? 218 TYR F CB  1 
ATOM   17426 C CG  . TYR F 1 218 ? -4.434  -0.800  35.883  1.00 27.26  ? 218 TYR F CG  1 
ATOM   17427 C CD1 . TYR F 1 218 ? -4.873  -1.502  36.986  1.00 25.05  ? 218 TYR F CD1 1 
ATOM   17428 C CD2 . TYR F 1 218 ? -4.437  -1.443  34.633  1.00 25.26  ? 218 TYR F CD2 1 
ATOM   17429 C CE1 . TYR F 1 218 ? -5.330  -2.797  36.871  1.00 31.29  ? 218 TYR F CE1 1 
ATOM   17430 C CE2 . TYR F 1 218 ? -4.893  -2.735  34.508  1.00 29.07  ? 218 TYR F CE2 1 
ATOM   17431 C CZ  . TYR F 1 218 ? -5.340  -3.406  35.630  1.00 32.13  ? 218 TYR F CZ  1 
ATOM   17432 O OH  . TYR F 1 218 ? -5.800  -4.687  35.524  1.00 38.34  ? 218 TYR F OH  1 
ATOM   17433 N N   . ALA F 1 219 ? -1.329  -1.457  35.604  1.00 28.49  ? 219 ALA F N   1 
ATOM   17434 C CA  . ALA F 1 219 ? -0.679  -2.349  34.656  1.00 29.88  ? 219 ALA F CA  1 
ATOM   17435 C C   . ALA F 1 219 ? -0.977  -3.781  35.073  1.00 31.49  ? 219 ALA F C   1 
ATOM   17436 O O   . ALA F 1 219 ? -0.804  -4.135  36.244  1.00 33.43  ? 219 ALA F O   1 
ATOM   17437 C CB  . ALA F 1 219 ? 0.836   -2.090  34.612  1.00 29.16  ? 219 ALA F CB  1 
ATOM   17438 N N   . ASN F 1 220 ? -1.397  -4.606  34.110  1.00 34.16  ? 220 ASN F N   1 
ATOM   17439 C CA  . ASN F 1 220 ? -1.841  -5.965  34.423  1.00 35.63  ? 220 ASN F CA  1 
ATOM   17440 C C   . ASN F 1 220 ? -0.773  -6.764  35.163  1.00 32.76  ? 220 ASN F C   1 
ATOM   17441 O O   . ASN F 1 220 ? -1.051  -7.385  36.194  1.00 36.50  ? 220 ASN F O   1 
ATOM   17442 C CB  . ASN F 1 220 ? -2.243  -6.683  33.144  1.00 35.60  ? 220 ASN F CB  1 
ATOM   17443 C CG  . ASN F 1 220 ? -3.580  -6.240  32.649  1.00 36.28  ? 220 ASN F CG  1 
ATOM   17444 O OD1 . ASN F 1 220 ? -4.534  -6.126  33.425  1.00 33.90  ? 220 ASN F OD1 1 
ATOM   17445 N ND2 . ASN F 1 220 ? -3.666  -5.958  31.351  1.00 37.78  ? 220 ASN F ND2 1 
ATOM   17446 N N   . ASP F 1 221 ? 0.450   -6.775  34.643  1.00 30.36  ? 221 ASP F N   1 
ATOM   17447 C CA  . ASP F 1 221 ? 1.520   -7.585  35.214  1.00 37.99  ? 221 ASP F CA  1 
ATOM   17448 C C   . ASP F 1 221 ? 2.137   -6.964  36.455  1.00 40.93  ? 221 ASP F C   1 
ATOM   17449 O O   . ASP F 1 221 ? 3.053   -7.553  37.037  1.00 42.76  ? 221 ASP F O   1 
ATOM   17450 C CB  . ASP F 1 221 ? 2.619   -7.813  34.177  1.00 39.24  ? 221 ASP F CB  1 
ATOM   17451 C CG  . ASP F 1 221 ? 3.009   -6.549  33.479  1.00 46.82  ? 221 ASP F CG  1 
ATOM   17452 O OD1 . ASP F 1 221 ? 4.227   -6.283  33.355  1.00 55.96  ? 221 ASP F OD1 1 
ATOM   17453 O OD2 . ASP F 1 221 ? 2.088   -5.813  33.053  1.00 51.16  ? 221 ASP F OD2 1 
ATOM   17454 N N   . GLN F 1 222 ? 1.692   -5.780  36.846  1.00 40.67  ? 222 GLN F N   1 
ATOM   17455 C CA  . GLN F 1 222 ? 2.065   -5.194  38.116  1.00 38.79  ? 222 GLN F CA  1 
ATOM   17456 C C   . GLN F 1 222 ? 0.933   -5.254  39.127  1.00 39.19  ? 222 GLN F C   1 
ATOM   17457 O O   . GLN F 1 222 ? 1.136   -4.881  40.287  1.00 41.45  ? 222 GLN F O   1 
ATOM   17458 C CB  . GLN F 1 222 ? 2.491   -3.745  37.902  1.00 43.52  ? 222 GLN F CB  1 
ATOM   17459 C CG  . GLN F 1 222 ? 3.562   -3.590  36.857  1.00 41.44  ? 222 GLN F CG  1 
ATOM   17460 C CD  . GLN F 1 222 ? 4.896   -3.318  37.486  1.00 46.12  ? 222 GLN F CD  1 
ATOM   17461 O OE1 . GLN F 1 222 ? 5.291   -3.989  38.446  1.00 55.10  ? 222 GLN F OE1 1 
ATOM   17462 N NE2 . GLN F 1 222 ? 5.598   -2.318  36.971  1.00 45.51  ? 222 GLN F NE2 1 
ATOM   17463 N N   . LEU F 1 223 ? -0.248  -5.727  38.715  1.00 33.53  ? 223 LEU F N   1 
ATOM   17464 C CA  . LEU F 1 223 ? -1.422  -5.647  39.579  1.00 38.00  ? 223 LEU F CA  1 
ATOM   17465 C C   . LEU F 1 223 ? -1.227  -6.406  40.887  1.00 39.64  ? 223 LEU F C   1 
ATOM   17466 O O   . LEU F 1 223 ? -1.676  -5.948  41.947  1.00 38.47  ? 223 LEU F O   1 
ATOM   17467 C CB  . LEU F 1 223 ? -2.652  -6.177  38.848  1.00 36.06  ? 223 LEU F CB  1 
ATOM   17468 C CG  . LEU F 1 223 ? -3.952  -5.812  39.573  1.00 38.63  ? 223 LEU F CG  1 
ATOM   17469 C CD1 . LEU F 1 223 ? -3.957  -4.332  40.033  1.00 31.78  ? 223 LEU F CD1 1 
ATOM   17470 C CD2 . LEU F 1 223 ? -5.140  -6.126  38.705  1.00 36.50  ? 223 LEU F CD2 1 
ATOM   17471 N N   . ASP F 1 224 ? -0.572  -7.573  40.833  1.00 35.74  ? 224 ASP F N   1 
ATOM   17472 C CA  . ASP F 1 224 ? -0.452  -8.418  42.021  1.00 35.36  ? 224 ASP F CA  1 
ATOM   17473 C C   . ASP F 1 224 ? 0.300   -7.697  43.131  1.00 38.60  ? 224 ASP F C   1 
ATOM   17474 O O   . ASP F 1 224 ? -0.180  -7.610  44.265  1.00 31.61  ? 224 ASP F O   1 
ATOM   17475 C CB  . ASP F 1 224 ? 0.255   -9.725  41.670  1.00 41.57  ? 224 ASP F CB  1 
ATOM   17476 C CG  . ASP F 1 224 ? -0.709  -10.824 41.232  1.00 52.96  ? 224 ASP F CG  1 
ATOM   17477 O OD1 . ASP F 1 224 ? -1.900  -10.788 41.622  1.00 48.13  ? 224 ASP F OD1 1 
ATOM   17478 O OD2 . ASP F 1 224 ? -0.256  -11.740 40.507  1.00 59.41  ? 224 ASP F OD2 1 
ATOM   17479 N N   . THR F 1 225 ? 1.485   -7.164  42.821  1.00 38.47  ? 225 THR F N   1 
ATOM   17480 C CA  . THR F 1 225 ? 2.247   -6.462  43.850  1.00 39.12  ? 225 THR F CA  1 
ATOM   17481 C C   . THR F 1 225 ? 1.652   -5.095  44.167  1.00 32.82  ? 225 THR F C   1 
ATOM   17482 O O   . THR F 1 225 ? 1.803   -4.614  45.294  1.00 32.70  ? 225 THR F O   1 
ATOM   17483 C CB  . THR F 1 225 ? 3.723   -6.348  43.443  1.00 37.07  ? 225 THR F CB  1 
ATOM   17484 O OG1 . THR F 1 225 ? 3.875   -5.434  42.344  1.00 35.07  ? 225 THR F OG1 1 
ATOM   17485 C CG2 . THR F 1 225 ? 4.278   -7.723  43.071  1.00 38.37  ? 225 THR F CG2 1 
ATOM   17486 N N   . LEU F 1 226 ? 0.969   -4.464  43.210  1.00 31.43  ? 226 LEU F N   1 
ATOM   17487 C CA  . LEU F 1 226 ? 0.227   -3.242  43.515  1.00 34.83  ? 226 LEU F CA  1 
ATOM   17488 C C   . LEU F 1 226 ? -0.719  -3.457  44.692  1.00 31.10  ? 226 LEU F C   1 
ATOM   17489 O O   . LEU F 1 226 ? -0.609  -2.794  45.731  1.00 29.81  ? 226 LEU F O   1 
ATOM   17490 C CB  . LEU F 1 226 ? -0.551  -2.774  42.286  1.00 37.37  ? 226 LEU F CB  1 
ATOM   17491 C CG  . LEU F 1 226 ? -1.021  -1.325  42.383  1.00 41.00  ? 226 LEU F CG  1 
ATOM   17492 C CD1 . LEU F 1 226 ? 0.159   -0.356  42.490  1.00 37.79  ? 226 LEU F CD1 1 
ATOM   17493 C CD2 . LEU F 1 226 ? -1.917  -0.964  41.216  1.00 39.89  ? 226 LEU F CD2 1 
ATOM   17494 N N   . ALA F 1 227 ? -1.639  -4.415  44.557  1.00 31.92  ? 227 ALA F N   1 
ATOM   17495 C CA  . ALA F 1 227 ? -2.660  -4.608  45.585  1.00 27.05  ? 227 ALA F CA  1 
ATOM   17496 C C   . ALA F 1 227 ? -2.046  -5.006  46.920  1.00 28.52  ? 227 ALA F C   1 
ATOM   17497 O O   . ALA F 1 227 ? -2.517  -4.563  47.966  1.00 28.05  ? 227 ALA F O   1 
ATOM   17498 C CB  . ALA F 1 227 ? -3.676  -5.657  45.137  1.00 28.77  ? 227 ALA F CB  1 
ATOM   17499 N N   . ASP F 1 228 ? -0.999  -5.848  46.915  1.00 26.85  ? 228 ASP F N   1 
ATOM   17500 C CA  . ASP F 1 228 ? -0.343  -6.179  48.182  1.00 28.11  ? 228 ASP F CA  1 
ATOM   17501 C C   . ASP F 1 228 ? 0.264   -4.933  48.825  1.00 27.42  ? 228 ASP F C   1 
ATOM   17502 O O   . ASP F 1 228 ? 0.084   -4.689  50.024  1.00 28.82  ? 228 ASP F O   1 
ATOM   17503 C CB  . ASP F 1 228 ? 0.739   -7.253  47.992  1.00 30.10  ? 228 ASP F CB  1 
ATOM   17504 C CG  . ASP F 1 228 ? 0.169   -8.616  47.550  1.00 42.58  ? 228 ASP F CG  1 
ATOM   17505 O OD1 . ASP F 1 228 ? -0.475  -9.313  48.371  1.00 39.97  ? 228 ASP F OD1 1 
ATOM   17506 O OD2 . ASP F 1 228 ? 0.419   -9.031  46.398  1.00 43.44  ? 228 ASP F OD2 1 
ATOM   17507 N N   . THR F 1 229 ? 0.994   -4.138  48.036  1.00 25.73  ? 229 THR F N   1 
ATOM   17508 C CA  . THR F 1 229 ? 1.621   -2.927  48.556  1.00 31.34  ? 229 THR F CA  1 
ATOM   17509 C C   . THR F 1 229 ? 0.577   -1.886  48.950  1.00 27.31  ? 229 THR F C   1 
ATOM   17510 O O   . THR F 1 229 ? 0.710   -1.240  49.993  1.00 25.37  ? 229 THR F O   1 
ATOM   17511 C CB  . THR F 1 229 ? 2.590   -2.344  47.523  1.00 31.05  ? 229 THR F CB  1 
ATOM   17512 O OG1 . THR F 1 229 ? 3.621   -3.290  47.236  1.00 29.25  ? 229 THR F OG1 1 
ATOM   17513 C CG2 . THR F 1 229 ? 3.240   -1.075  48.053  1.00 34.70  ? 229 THR F CG2 1 
ATOM   17514 N N   . LEU F 1 230 ? -0.462  -1.707  48.126  1.00 27.52  ? 230 LEU F N   1 
ATOM   17515 C CA  . LEU F 1 230 ? -1.541  -0.787  48.481  1.00 29.64  ? 230 LEU F CA  1 
ATOM   17516 C C   . LEU F 1 230 ? -2.189  -1.194  49.800  1.00 27.30  ? 230 LEU F C   1 
ATOM   17517 O O   . LEU F 1 230 ? -2.382  -0.367  50.706  1.00 22.33  ? 230 LEU F O   1 
ATOM   17518 C CB  . LEU F 1 230 ? -2.581  -0.746  47.361  1.00 28.80  ? 230 LEU F CB  1 
ATOM   17519 C CG  . LEU F 1 230 ? -2.329  0.291   46.268  1.00 26.10  ? 230 LEU F CG  1 
ATOM   17520 C CD1 . LEU F 1 230 ? -3.516  0.355   45.352  1.00 28.88  ? 230 LEU F CD1 1 
ATOM   17521 C CD2 . LEU F 1 230 ? -2.091  1.635   46.884  1.00 24.08  ? 230 LEU F CD2 1 
ATOM   17522 N N   . TRP F 1 231 ? -2.482  -2.485  49.937  1.00 24.36  ? 231 TRP F N   1 
ATOM   17523 C CA  . TRP F 1 231 ? -3.075  -3.000  51.166  1.00 28.20  ? 231 TRP F CA  1 
ATOM   17524 C C   . TRP F 1 231 ? -2.230  -2.667  52.399  1.00 29.80  ? 231 TRP F C   1 
ATOM   17525 O O   . TRP F 1 231 ? -2.740  -2.125  53.384  1.00 33.46  ? 231 TRP F O   1 
ATOM   17526 C CB  . TRP F 1 231 ? -3.273  -4.513  51.052  1.00 21.45  ? 231 TRP F CB  1 
ATOM   17527 C CG  . TRP F 1 231 ? -3.868  -5.078  52.290  1.00 28.54  ? 231 TRP F CG  1 
ATOM   17528 C CD1 . TRP F 1 231 ? -3.232  -5.799  53.250  1.00 20.97  ? 231 TRP F CD1 1 
ATOM   17529 C CD2 . TRP F 1 231 ? -5.232  -4.944  52.719  1.00 23.04  ? 231 TRP F CD2 1 
ATOM   17530 N NE1 . TRP F 1 231 ? -4.118  -6.129  54.255  1.00 24.01  ? 231 TRP F NE1 1 
ATOM   17531 C CE2 . TRP F 1 231 ? -5.354  -5.627  53.947  1.00 26.33  ? 231 TRP F CE2 1 
ATOM   17532 C CE3 . TRP F 1 231 ? -6.358  -4.328  52.181  1.00 22.34  ? 231 TRP F CE3 1 
ATOM   17533 C CZ2 . TRP F 1 231 ? -6.572  -5.714  54.643  1.00 22.29  ? 231 TRP F CZ2 1 
ATOM   17534 C CZ3 . TRP F 1 231 ? -7.572  -4.412  52.885  1.00 20.34  ? 231 TRP F CZ3 1 
ATOM   17535 C CH2 . TRP F 1 231 ? -7.657  -5.079  54.098  1.00 20.52  ? 231 TRP F CH2 1 
ATOM   17536 N N   . SER F 1 232 ? -0.937  -3.002  52.378  1.00 25.82  ? 232 SER F N   1 
ATOM   17537 C CA  . SER F 1 232 ? -0.118  -2.797  53.577  1.00 32.73  ? 232 SER F CA  1 
ATOM   17538 C C   . SER F 1 232 ? 0.086   -1.310  53.879  1.00 27.84  ? 232 SER F C   1 
ATOM   17539 O O   . SER F 1 232 ? 0.112   -0.908  55.046  1.00 35.18  ? 232 SER F O   1 
ATOM   17540 C CB  . SER F 1 232 ? 1.231   -3.511  53.424  1.00 29.77  ? 232 SER F CB  1 
ATOM   17541 O OG  . SER F 1 232 ? 1.037   -4.874  53.095  1.00 37.09  ? 232 SER F OG  1 
ATOM   17542 N N   . GLN F 1 233 ? 0.195   -0.478  52.844  1.00 25.20  ? 233 GLN F N   1 
ATOM   17543 C CA  . GLN F 1 233 ? 0.378   0.962   53.043  1.00 28.82  ? 233 GLN F CA  1 
ATOM   17544 C C   . GLN F 1 233 ? -0.849  1.636   53.664  1.00 33.70  ? 233 GLN F C   1 
ATOM   17545 O O   . GLN F 1 233 ? -0.718  2.545   54.503  1.00 29.23  ? 233 GLN F O   1 
ATOM   17546 C CB  . GLN F 1 233 ? 0.709   1.623   51.710  1.00 27.62  ? 233 GLN F CB  1 
ATOM   17547 C CG  . GLN F 1 233 ? 2.103   1.278   51.160  1.00 35.60  ? 233 GLN F CG  1 
ATOM   17548 C CD  . GLN F 1 233 ? 2.872   2.536   50.852  1.00 40.34  ? 233 GLN F CD  1 
ATOM   17549 O OE1 . GLN F 1 233 ? 2.410   3.618   51.187  1.00 47.16  ? 233 GLN F OE1 1 
ATOM   17550 N NE2 . GLN F 1 233 ? 4.026   2.414   50.207  1.00 37.22  ? 233 GLN F NE2 1 
ATOM   17551 N N   . LEU F 1 234 ? -2.049  1.238   53.249  1.00 28.69  ? 234 LEU F N   1 
ATOM   17552 C CA  . LEU F 1 234 ? -3.254  1.940   53.669  1.00 29.26  ? 234 LEU F CA  1 
ATOM   17553 C C   . LEU F 1 234 ? -4.000  1.230   54.798  1.00 27.55  ? 234 LEU F C   1 
ATOM   17554 O O   . LEU F 1 234 ? -5.101  1.656   55.171  1.00 28.61  ? 234 LEU F O   1 
ATOM   17555 C CB  . LEU F 1 234 ? -4.179  2.157   52.469  1.00 27.15  ? 234 LEU F CB  1 
ATOM   17556 C CG  . LEU F 1 234 ? -3.618  2.932   51.282  1.00 27.19  ? 234 LEU F CG  1 
ATOM   17557 C CD1 . LEU F 1 234 ? -4.637  2.985   50.161  1.00 29.88  ? 234 LEU F CD1 1 
ATOM   17558 C CD2 . LEU F 1 234 ? -3.206  4.331   51.688  1.00 33.09  ? 234 LEU F CD2 1 
ATOM   17559 N N   . THR F 1 235 ? -3.430  0.173   55.360  1.00 29.02  ? 235 THR F N   1 
ATOM   17560 C CA  . THR F 1 235 ? -4.031  -0.500  56.500  1.00 27.52  ? 235 THR F CA  1 
ATOM   17561 C C   . THR F 1 235 ? -3.091  -0.410  57.688  1.00 33.50  ? 235 THR F C   1 
ATOM   17562 O O   . THR F 1 235 ? -1.892  -0.139  57.536  1.00 33.27  ? 235 THR F O   1 
ATOM   17563 C CB  . THR F 1 235 ? -4.338  -1.960  56.192  1.00 24.22  ? 235 THR F CB  1 
ATOM   17564 O OG1 . THR F 1 235 ? -3.139  -2.622  55.785  1.00 27.91  ? 235 THR F OG1 1 
ATOM   17565 C CG2 . THR F 1 235 ? -5.377  -2.062  55.064  1.00 21.73  ? 235 THR F CG2 1 
ATOM   17566 N N   . ASP F 1 236 ? -3.657  -0.617  58.877  1.00 30.15  ? 236 ASP F N   1 
ATOM   17567 C CA  . ASP F 1 236 ? -2.879  -0.782  60.099  1.00 28.73  ? 236 ASP F CA  1 
ATOM   17568 C C   . ASP F 1 236 ? -3.614  -1.773  61.007  1.00 37.30  ? 236 ASP F C   1 
ATOM   17569 O O   . ASP F 1 236 ? -4.623  -2.375  60.616  1.00 32.05  ? 236 ASP F O   1 
ATOM   17570 C CB  . ASP F 1 236 ? -2.599  0.582   60.768  1.00 34.59  ? 236 ASP F CB  1 
ATOM   17571 C CG  . ASP F 1 236 ? -3.862  1.324   61.201  1.00 32.24  ? 236 ASP F CG  1 
ATOM   17572 O OD1 . ASP F 1 236 ? -4.936  0.697   61.311  1.00 32.58  ? 236 ASP F OD1 1 
ATOM   17573 O OD2 . ASP F 1 236 ? -3.780  2.557   61.426  1.00 33.17  ? 236 ASP F OD2 1 
ATOM   17574 N N   . THR F 1 237 ? -3.100  -1.946  62.229  1.00 34.18  ? 237 THR F N   1 
ATOM   17575 C CA  . THR F 1 237 ? -3.649  -2.964  63.117  1.00 33.01  ? 237 THR F CA  1 
ATOM   17576 C C   . THR F 1 237 ? -5.132  -2.725  63.388  1.00 34.05  ? 237 THR F C   1 
ATOM   17577 O O   . THR F 1 237 ? -5.911  -3.680  63.478  1.00 30.49  ? 237 THR F O   1 
ATOM   17578 C CB  . THR F 1 237 ? -2.841  -3.018  64.423  1.00 35.04  ? 237 THR F CB  1 
ATOM   17579 O OG1 . THR F 1 237 ? -1.608  -3.715  64.192  1.00 42.57  ? 237 THR F OG1 1 
ATOM   17580 C CG2 . THR F 1 237 ? -3.588  -3.774  65.495  1.00 35.19  ? 237 THR F CG2 1 
ATOM   17581 N N   . GLN F 1 238 ? -5.555  -1.463  63.480  1.00 28.06  ? 238 GLN F N   1 
ATOM   17582 C CA  . GLN F 1 238 ? -6.948  -1.186  63.803  1.00 33.23  ? 238 GLN F CA  1 
ATOM   17583 C C   . GLN F 1 238 ? -7.839  -1.068  62.580  1.00 34.81  ? 238 GLN F C   1 
ATOM   17584 O O   . GLN F 1 238 ? -9.058  -1.225  62.704  1.00 37.34  ? 238 GLN F O   1 
ATOM   17585 C CB  . GLN F 1 238 ? -7.075  0.101   64.614  1.00 34.31  ? 238 GLN F CB  1 
ATOM   17586 C CG  . GLN F 1 238 ? -6.334  0.083   65.927  1.00 38.29  ? 238 GLN F CG  1 
ATOM   17587 C CD  . GLN F 1 238 ? -4.992  0.768   65.818  1.00 38.94  ? 238 GLN F CD  1 
ATOM   17588 O OE1 . GLN F 1 238 ? -4.196  0.483   64.909  1.00 35.32  ? 238 GLN F OE1 1 
ATOM   17589 N NE2 . GLN F 1 238 ? -4.742  1.707   66.725  1.00 46.77  ? 238 GLN F NE2 1 
ATOM   17590 N N   . ASN F 1 239 ? -7.269  -0.796  61.411  1.00 32.09  ? 239 ASN F N   1 
ATOM   17591 C CA  . ASN F 1 239 ? -8.035  -0.529  60.196  1.00 34.79  ? 239 ASN F CA  1 
ATOM   17592 C C   . ASN F 1 239 ? -7.689  -1.593  59.161  1.00 31.12  ? 239 ASN F C   1 
ATOM   17593 O O   . ASN F 1 239 ? -6.709  -1.468  58.419  1.00 28.71  ? 239 ASN F O   1 
ATOM   17594 C CB  . ASN F 1 239 ? -7.759  0.886   59.698  1.00 32.46  ? 239 ASN F CB  1 
ATOM   17595 C CG  . ASN F 1 239 ? -8.317  1.917   60.640  1.00 35.25  ? 239 ASN F CG  1 
ATOM   17596 O OD1 . ASN F 1 239 ? -9.500  1.874   60.946  1.00 37.63  ? 239 ASN F OD1 1 
ATOM   17597 N ND2 . ASN F 1 239 ? -7.477  2.818   61.137  1.00 32.03  ? 239 ASN F ND2 1 
ATOM   17598 N N   . GLN F 1 240 ? -8.500  -2.652  59.140  1.00 28.13  ? 240 GLN F N   1 
ATOM   17599 C CA  . GLN F 1 240 ? -8.350  -3.752  58.200  1.00 30.43  ? 240 GLN F CA  1 
ATOM   17600 C C   . GLN F 1 240 ? -9.304  -3.623  57.023  1.00 25.60  ? 240 GLN F C   1 
ATOM   17601 O O   . GLN F 1 240 ? -9.656  -4.629  56.406  1.00 29.74  ? 240 GLN F O   1 
ATOM   17602 C CB  . GLN F 1 240 ? -8.560  -5.095  58.911  1.00 28.33  ? 240 GLN F CB  1 
ATOM   17603 C CG  . GLN F 1 240 ? -7.394  -5.566  59.759  1.00 26.68  ? 240 GLN F CG  1 
ATOM   17604 C CD  . GLN F 1 240 ? -6.111  -5.659  58.971  1.00 26.77  ? 240 GLN F CD  1 
ATOM   17605 O OE1 . GLN F 1 240 ? -5.240  -4.797  59.077  1.00 32.64  ? 240 GLN F OE1 1 
ATOM   17606 N NE2 . GLN F 1 240 ? -5.992  -6.701  58.159  1.00 32.75  ? 240 GLN F NE2 1 
ATOM   17607 N N   . PHE F 1 241 ? -9.752  -2.410  56.726  1.00 25.40  ? 241 PHE F N   1 
ATOM   17608 C CA  . PHE F 1 241 ? -10.577 -2.122  55.566  1.00 21.88  ? 241 PHE F CA  1 
ATOM   17609 C C   . PHE F 1 241 ? -9.874  -1.091  54.705  1.00 25.49  ? 241 PHE F C   1 
ATOM   17610 O O   . PHE F 1 241 ? -9.267  -0.146  55.218  1.00 26.74  ? 241 PHE F O   1 
ATOM   17611 C CB  . PHE F 1 241 ? -11.969 -1.558  55.941  1.00 27.52  ? 241 PHE F CB  1 
ATOM   17612 C CG  . PHE F 1 241 ? -12.929 -2.568  56.526  1.00 26.49  ? 241 PHE F CG  1 
ATOM   17613 C CD1 . PHE F 1 241 ? -12.907 -3.898  56.138  1.00 27.75  ? 241 PHE F CD1 1 
ATOM   17614 C CD2 . PHE F 1 241 ? -13.880 -2.158  57.447  1.00 29.48  ? 241 PHE F CD2 1 
ATOM   17615 C CE1 . PHE F 1 241 ? -13.809 -4.816  56.683  1.00 28.56  ? 241 PHE F CE1 1 
ATOM   17616 C CE2 . PHE F 1 241 ? -14.783 -3.061  58.006  1.00 29.92  ? 241 PHE F CE2 1 
ATOM   17617 C CZ  . PHE F 1 241 ? -14.746 -4.389  57.626  1.00 33.42  ? 241 PHE F CZ  1 
ATOM   17618 N N   . ILE F 1 242 ? -9.994  -1.267  53.402  1.00 21.31  ? 242 ILE F N   1 
ATOM   17619 C CA  . ILE F 1 242 ? -9.664  -0.260  52.416  1.00 21.22  ? 242 ILE F CA  1 
ATOM   17620 C C   . ILE F 1 242 ? -10.886 -0.018  51.553  1.00 22.18  ? 242 ILE F C   1 
ATOM   17621 O O   . ILE F 1 242 ? -11.669 -0.932  51.281  1.00 24.22  ? 242 ILE F O   1 
ATOM   17622 C CB  . ILE F 1 242 ? -8.457  -0.712  51.573  1.00 30.65  ? 242 ILE F CB  1 
ATOM   17623 C CG1 . ILE F 1 242 ? -7.170  -0.256  52.242  1.00 26.63  ? 242 ILE F CG1 1 
ATOM   17624 C CG2 . ILE F 1 242 ? -8.550  -0.264  50.123  1.00 20.26  ? 242 ILE F CG2 1 
ATOM   17625 C CD1 . ILE F 1 242 ? -5.973  -0.676  51.441  1.00 38.03  ? 242 ILE F CD1 1 
ATOM   17626 N N   . THR F 1 243 ? -11.043 1.237   51.143  1.00 21.53  ? 243 THR F N   1 
ATOM   17627 C CA  . THR F 1 243 ? -12.064 1.682   50.213  1.00 24.36  ? 243 THR F CA  1 
ATOM   17628 C C   . THR F 1 243 ? -11.414 1.843   48.833  1.00 25.45  ? 243 THR F C   1 
ATOM   17629 O O   . THR F 1 243 ? -10.332 2.424   48.729  1.00 25.01  ? 243 THR F O   1 
ATOM   17630 C CB  . THR F 1 243 ? -12.659 2.993   50.743  1.00 21.88  ? 243 THR F CB  1 
ATOM   17631 O OG1 . THR F 1 243 ? -13.794 2.687   51.565  1.00 25.45  ? 243 THR F OG1 1 
ATOM   17632 C CG2 . THR F 1 243 ? -13.060 3.900   49.659  1.00 29.94  ? 243 THR F CG2 1 
ATOM   17633 N N   . VAL F 1 244 ? -12.040 1.266   47.800  1.00 22.33  ? 244 VAL F N   1 
ATOM   17634 C CA  . VAL F 1 244 ? -11.607 1.347   46.405  1.00 25.55  ? 244 VAL F CA  1 
ATOM   17635 C C   . VAL F 1 244 ? -12.806 1.803   45.586  1.00 21.35  ? 244 VAL F C   1 
ATOM   17636 O O   . VAL F 1 244 ? -13.850 1.149   45.615  1.00 25.74  ? 244 VAL F O   1 
ATOM   17637 C CB  . VAL F 1 244 ? -11.089 -0.001  45.865  1.00 25.16  ? 244 VAL F CB  1 
ATOM   17638 C CG1 . VAL F 1 244 ? -10.390 0.216   44.568  1.00 20.74  ? 244 VAL F CG1 1 
ATOM   17639 C CG2 . VAL F 1 244 ? -10.125 -0.675  46.852  1.00 20.95  ? 244 VAL F CG2 1 
ATOM   17640 N N   . GLU F 1 245 ? -12.667 2.919   44.870  1.00 18.27  ? 245 GLU F N   1 
ATOM   17641 C CA  . GLU F 1 245 ? -13.791 3.517   44.169  1.00 22.07  ? 245 GLU F CA  1 
ATOM   17642 C C   . GLU F 1 245 ? -13.397 3.977   42.779  1.00 19.73  ? 245 GLU F C   1 
ATOM   17643 O O   . GLU F 1 245 ? -12.260 4.359   42.520  1.00 22.99  ? 245 GLU F O   1 
ATOM   17644 C CB  . GLU F 1 245 ? -14.368 4.743   44.929  1.00 19.76  ? 245 GLU F CB  1 
ATOM   17645 C CG  . GLU F 1 245 ? -14.810 4.403   46.335  1.00 26.87  ? 245 GLU F CG  1 
ATOM   17646 C CD  . GLU F 1 245 ? -14.991 5.618   47.210  1.00 26.36  ? 245 GLU F CD  1 
ATOM   17647 O OE1 . GLU F 1 245 ? -14.397 6.681   46.909  1.00 28.32  ? 245 GLU F OE1 1 
ATOM   17648 O OE2 . GLU F 1 245 ? -15.733 5.499   48.207  1.00 31.99  ? 245 GLU F OE2 1 
ATOM   17649 N N   . THR F 1 246 ? -14.380 3.998   41.905  1.00 23.17  ? 246 THR F N   1 
ATOM   17650 C CA  . THR F 1 246 ? -14.211 4.662   40.629  1.00 25.27  ? 246 THR F CA  1 
ATOM   17651 C C   . THR F 1 246 ? -14.040 6.154   40.860  1.00 21.75  ? 246 THR F C   1 
ATOM   17652 O O   . THR F 1 246 ? -14.803 6.763   41.613  1.00 22.07  ? 246 THR F O   1 
ATOM   17653 C CB  . THR F 1 246 ? -15.423 4.394   39.747  1.00 27.62  ? 246 THR F CB  1 
ATOM   17654 O OG1 . THR F 1 246 ? -15.571 2.977   39.576  1.00 24.37  ? 246 THR F OG1 1 
ATOM   17655 C CG2 . THR F 1 246 ? -15.251 5.088   38.401  1.00 26.39  ? 246 THR F CG2 1 
ATOM   17656 N N   . TYR F 1 247 ? -13.032 6.739   40.230  1.00 20.76  ? 247 TYR F N   1 
ATOM   17657 C CA  . TYR F 1 247 ? -12.754 8.158   40.363  1.00 23.22  ? 247 TYR F CA  1 
ATOM   17658 C C   . TYR F 1 247 ? -13.315 8.908   39.155  1.00 24.87  ? 247 TYR F C   1 
ATOM   17659 O O   . TYR F 1 247 ? -13.095 8.503   38.009  1.00 24.93  ? 247 TYR F O   1 
ATOM   17660 C CB  . TYR F 1 247 ? -11.250 8.386   40.507  1.00 23.66  ? 247 TYR F CB  1 
ATOM   17661 C CG  . TYR F 1 247 ? -10.900 9.812   40.867  1.00 27.15  ? 247 TYR F CG  1 
ATOM   17662 C CD1 . TYR F 1 247 ? -10.908 10.242  42.192  1.00 26.50  ? 247 TYR F CD1 1 
ATOM   17663 C CD2 . TYR F 1 247 ? -10.570 10.730  39.878  1.00 29.57  ? 247 TYR F CD2 1 
ATOM   17664 C CE1 . TYR F 1 247 ? -10.592 11.562  42.519  1.00 27.48  ? 247 TYR F CE1 1 
ATOM   17665 C CE2 . TYR F 1 247 ? -10.252 12.035  40.192  1.00 32.80  ? 247 TYR F CE2 1 
ATOM   17666 C CZ  . TYR F 1 247 ? -10.266 12.443  41.509  1.00 33.03  ? 247 TYR F CZ  1 
ATOM   17667 O OH  . TYR F 1 247 ? -9.948  13.739  41.791  1.00 38.78  ? 247 TYR F OH  1 
ATOM   17668 N N   . HIS F 1 248 ? -14.062 9.976   39.412  1.00 19.07  ? 248 HIS F N   1 
ATOM   17669 C CA  . HIS F 1 248 ? -14.637 10.794  38.353  1.00 30.15  ? 248 HIS F CA  1 
ATOM   17670 C C   . HIS F 1 248 ? -13.945 12.148  38.298  1.00 31.24  ? 248 HIS F C   1 
ATOM   17671 O O   . HIS F 1 248 ? -13.597 12.724  39.334  1.00 29.75  ? 248 HIS F O   1 
ATOM   17672 C CB  . HIS F 1 248 ? -16.146 10.993  38.552  1.00 25.03  ? 248 HIS F CB  1 
ATOM   17673 C CG  . HIS F 1 248 ? -16.924 9.717   38.540  1.00 27.99  ? 248 HIS F CG  1 
ATOM   17674 N ND1 . HIS F 1 248 ? -17.543 9.232   37.407  1.00 30.73  ? 248 HIS F ND1 1 
ATOM   17675 C CD2 . HIS F 1 248 ? -17.164 8.811   39.517  1.00 28.05  ? 248 HIS F CD2 1 
ATOM   17676 C CE1 . HIS F 1 248 ? -18.131 8.084   37.687  1.00 26.38  ? 248 HIS F CE1 1 
ATOM   17677 N NE2 . HIS F 1 248 ? -17.921 7.807   38.962  1.00 27.90  ? 248 HIS F NE2 1 
ATOM   17678 N N   . ARG F 1 249 ? -13.740 12.649  37.087  1.00 34.51  ? 249 ARG F N   1 
ATOM   17679 C CA  . ARG F 1 249 ? -13.295 14.026  36.923  1.00 34.26  ? 249 ARG F CA  1 
ATOM   17680 C C   . ARG F 1 249 ? -14.448 14.967  37.260  1.00 38.12  ? 249 ARG F C   1 
ATOM   17681 O O   . ARG F 1 249 ? -15.571 14.785  36.782  1.00 39.53  ? 249 ARG F O   1 
ATOM   17682 C CB  . ARG F 1 249 ? -12.800 14.267  35.499  1.00 37.34  ? 249 ARG F CB  1 
ATOM   17683 C CG  . ARG F 1 249 ? -12.335 15.708  35.245  1.00 49.07  ? 249 ARG F CG  1 
ATOM   17684 C CD  . ARG F 1 249 ? -11.810 15.897  33.831  1.00 51.96  ? 249 ARG F CD  1 
ATOM   17685 N NE  . ARG F 1 249 ? -12.108 17.224  33.297  1.00 61.14  ? 249 ARG F NE  1 
ATOM   17686 C CZ  . ARG F 1 249 ? -13.217 17.542  32.639  1.00 61.19  ? 249 ARG F CZ  1 
ATOM   17687 N NH1 . ARG F 1 249 ? -14.202 16.670  32.479  1.00 60.76  ? 249 ARG F NH1 1 
ATOM   17688 N NH2 . ARG F 1 249 ? -13.339 18.763  32.123  1.00 60.50  ? 249 ARG F NH2 1 
ATOM   17689 N N   . ALA F 1 250 ? -14.174 15.970  38.087  1.00 34.72  ? 250 ALA F N   1 
ATOM   17690 C CA  . ALA F 1 250 ? -15.218 16.771  38.707  1.00 36.24  ? 250 ALA F CA  1 
ATOM   17691 C C   . ALA F 1 250 ? -15.311 18.138  38.045  1.00 42.41  ? 250 ALA F C   1 
ATOM   17692 O O   . ALA F 1 250 ? -14.294 18.819  37.863  1.00 41.91  ? 250 ALA F O   1 
ATOM   17693 C CB  . ALA F 1 250 ? -14.951 16.930  40.203  1.00 37.75  ? 250 ALA F CB  1 
ATOM   17694 N N   . ASP F 1 251 ? -16.532 18.530  37.675  1.00 41.62  ? 251 ASP F N   1 
ATOM   17695 C CA  . ASP F 1 251 ? -16.766 19.909  37.266  1.00 42.70  ? 251 ASP F CA  1 
ATOM   17696 C C   . ASP F 1 251 ? -16.659 20.850  38.457  1.00 43.68  ? 251 ASP F C   1 
ATOM   17697 O O   . ASP F 1 251 ? -16.061 21.929  38.361  1.00 48.82  ? 251 ASP F O   1 
ATOM   17698 C CB  . ASP F 1 251 ? -18.133 20.044  36.599  1.00 44.91  ? 251 ASP F CB  1 
ATOM   17699 C CG  . ASP F 1 251 ? -18.204 21.246  35.679  1.00 53.83  ? 251 ASP F CG  1 
ATOM   17700 O OD1 . ASP F 1 251 ? -17.629 21.172  34.570  1.00 58.42  ? 251 ASP F OD1 1 
ATOM   17701 O OD2 . ASP F 1 251 ? -18.808 22.271  36.076  1.00 53.35  ? 251 ASP F OD2 1 
ATOM   17702 N N   . GLN F 1 252 ? -17.226 20.454  39.591  1.00 39.04  ? 252 GLN F N   1 
ATOM   17703 C CA  . GLN F 1 252 ? -17.152 21.253  40.797  1.00 39.09  ? 252 GLN F CA  1 
ATOM   17704 C C   . GLN F 1 252 ? -17.071 20.341  42.008  1.00 35.98  ? 252 GLN F C   1 
ATOM   17705 O O   . GLN F 1 252 ? -17.714 19.291  42.047  1.00 32.77  ? 252 GLN F O   1 
ATOM   17706 C CB  . GLN F 1 252 ? -18.362 22.164  40.923  1.00 43.29  ? 252 GLN F CB  1 
ATOM   17707 C CG  . GLN F 1 252 ? -18.068 23.416  41.720  1.00 48.17  ? 252 GLN F CG  1 
ATOM   17708 C CD  . GLN F 1 252 ? -17.809 24.648  40.876  1.00 48.54  ? 252 GLN F CD  1 
ATOM   17709 O OE1 . GLN F 1 252 ? -17.989 24.645  39.654  1.00 48.37  ? 252 GLN F OE1 1 
ATOM   17710 N NE2 . GLN F 1 252 ? -17.373 25.718  41.534  1.00 47.42  ? 252 GLN F NE2 1 
ATOM   17711 N N   . ARG F 1 253 ? -16.298 20.769  43.001  1.00 35.20  ? 253 ARG F N   1 
ATOM   17712 C CA  . ARG F 1 253 ? -15.978 19.986  44.192  1.00 35.26  ? 253 ARG F CA  1 
ATOM   17713 C C   . ARG F 1 253 ? -16.364 20.799  45.421  1.00 36.11  ? 253 ARG F C   1 
ATOM   17714 O O   . ARG F 1 253 ? -15.727 21.816  45.709  1.00 41.86  ? 253 ARG F O   1 
ATOM   17715 C CB  . ARG F 1 253 ? -14.490 19.656  44.247  1.00 38.10  ? 253 ARG F CB  1 
ATOM   17716 C CG  . ARG F 1 253 ? -14.021 18.572  43.318  1.00 40.86  ? 253 ARG F CG  1 
ATOM   17717 C CD  . ARG F 1 253 ? -12.503 18.390  43.403  1.00 43.63  ? 253 ARG F CD  1 
ATOM   17718 N NE  . ARG F 1 253 ? -12.057 17.341  42.489  1.00 47.26  ? 253 ARG F NE  1 
ATOM   17719 C CZ  . ARG F 1 253 ? -11.653 17.545  41.240  1.00 49.65  ? 253 ARG F CZ  1 
ATOM   17720 N NH1 . ARG F 1 253 ? -11.456 18.768  40.766  1.00 42.00  ? 253 ARG F NH1 1 
ATOM   17721 N NH2 . ARG F 1 253 ? -11.449 16.493  40.445  1.00 48.55  ? 253 ARG F NH2 1 
ATOM   17722 N N   . PHE F 1 254 ? -17.359 20.329  46.167  1.00 28.79  ? 254 PHE F N   1 
ATOM   17723 C CA  . PHE F 1 254 ? -17.973 21.071  47.255  1.00 25.80  ? 254 PHE F CA  1 
ATOM   17724 C C   . PHE F 1 254 ? -18.013 20.252  48.542  1.00 23.20  ? 254 PHE F C   1 
ATOM   17725 O O   . PHE F 1 254 ? -17.828 19.029  48.561  1.00 20.30  ? 254 PHE F O   1 
ATOM   17726 C CB  . PHE F 1 254 ? -19.407 21.475  46.896  1.00 25.44  ? 254 PHE F CB  1 
ATOM   17727 C CG  . PHE F 1 254 ? -20.338 20.304  46.791  1.00 22.07  ? 254 PHE F CG  1 
ATOM   17728 C CD1 . PHE F 1 254 ? -20.467 19.615  45.602  1.00 23.86  ? 254 PHE F CD1 1 
ATOM   17729 C CD2 . PHE F 1 254 ? -21.082 19.891  47.884  1.00 24.17  ? 254 PHE F CD2 1 
ATOM   17730 C CE1 . PHE F 1 254 ? -21.306 18.518  45.503  1.00 21.59  ? 254 PHE F CE1 1 
ATOM   17731 C CE2 . PHE F 1 254 ? -21.928 18.786  47.792  1.00 22.28  ? 254 PHE F CE2 1 
ATOM   17732 C CZ  . PHE F 1 254 ? -22.030 18.099  46.607  1.00 22.73  ? 254 PHE F CZ  1 
ATOM   17733 N N   . PHE F 1 255 ? -18.288 20.954  49.631  1.00 21.19  ? 255 PHE F N   1 
ATOM   17734 C CA  . PHE F 1 255 ? -18.790 20.290  50.819  1.00 25.50  ? 255 PHE F CA  1 
ATOM   17735 C C   . PHE F 1 255 ? -19.766 21.208  51.530  1.00 22.56  ? 255 PHE F C   1 
ATOM   17736 O O   . PHE F 1 255 ? -19.754 22.425  51.343  1.00 23.81  ? 255 PHE F O   1 
ATOM   17737 C CB  . PHE F 1 255 ? -17.657 19.824  51.745  1.00 21.44  ? 255 PHE F CB  1 
ATOM   17738 C CG  . PHE F 1 255 ? -16.892 20.924  52.451  1.00 25.48  ? 255 PHE F CG  1 
ATOM   17739 C CD1 . PHE F 1 255 ? -15.760 21.501  51.856  1.00 24.63  ? 255 PHE F CD1 1 
ATOM   17740 C CD2 . PHE F 1 255 ? -17.229 21.300  53.746  1.00 24.18  ? 255 PHE F CD2 1 
ATOM   17741 C CE1 . PHE F 1 255 ? -14.998 22.465  52.519  1.00 23.31  ? 255 PHE F CE1 1 
ATOM   17742 C CE2 . PHE F 1 255 ? -16.471 22.278  54.425  1.00 31.88  ? 255 PHE F CE2 1 
ATOM   17743 C CZ  . PHE F 1 255 ? -15.342 22.854  53.802  1.00 27.94  ? 255 PHE F CZ  1 
ATOM   17744 N N   . PHE F 1 256 ? -20.635 20.592  52.321  1.00 21.96  ? 256 PHE F N   1 
ATOM   17745 C CA  . PHE F 1 256 ? -21.587 21.273  53.184  1.00 20.78  ? 256 PHE F CA  1 
ATOM   17746 C C   . PHE F 1 256 ? -21.223 20.949  54.622  1.00 18.82  ? 256 PHE F C   1 
ATOM   17747 O O   . PHE F 1 256 ? -20.898 19.807  54.934  1.00 23.69  ? 256 PHE F O   1 
ATOM   17748 C CB  . PHE F 1 256 ? -23.038 20.821  52.926  1.00 19.35  ? 256 PHE F CB  1 
ATOM   17749 C CG  . PHE F 1 256 ? -23.473 20.883  51.488  1.00 21.85  ? 256 PHE F CG  1 
ATOM   17750 C CD1 . PHE F 1 256 ? -23.047 21.912  50.645  1.00 19.66  ? 256 PHE F CD1 1 
ATOM   17751 C CD2 . PHE F 1 256 ? -24.347 19.923  50.981  1.00 19.34  ? 256 PHE F CD2 1 
ATOM   17752 C CE1 . PHE F 1 256 ? -23.473 21.978  49.322  1.00 21.86  ? 256 PHE F CE1 1 
ATOM   17753 C CE2 . PHE F 1 256 ? -24.779 19.977  49.653  1.00 22.17  ? 256 PHE F CE2 1 
ATOM   17754 C CZ  . PHE F 1 256 ? -24.339 21.003  48.815  1.00 21.98  ? 256 PHE F CZ  1 
ATOM   17755 N N   . GLU F 1 257 ? -21.272 21.941  55.495  1.00 20.50  ? 257 GLU F N   1 
ATOM   17756 C CA  . GLU F 1 257 ? -21.063 21.741  56.923  1.00 23.03  ? 257 GLU F CA  1 
ATOM   17757 C C   . GLU F 1 257 ? -22.349 22.059  57.681  1.00 18.13  ? 257 GLU F C   1 
ATOM   17758 O O   . GLU F 1 257 ? -23.052 23.013  57.348  1.00 20.50  ? 257 GLU F O   1 
ATOM   17759 C CB  . GLU F 1 257 ? -19.926 22.624  57.438  1.00 21.77  ? 257 GLU F CB  1 
ATOM   17760 C CG  . GLU F 1 257 ? -19.482 22.296  58.859  1.00 19.10  ? 257 GLU F CG  1 
ATOM   17761 C CD  . GLU F 1 257 ? -18.072 22.794  59.163  1.00 24.51  ? 257 GLU F CD  1 
ATOM   17762 O OE1 . GLU F 1 257 ? -17.577 23.704  58.439  1.00 23.49  ? 257 GLU F OE1 1 
ATOM   17763 O OE2 . GLU F 1 257 ? -17.459 22.269  60.113  1.00 16.94  ? 257 GLU F OE2 1 
ATOM   17764 N N   . TYR F 1 258 ? -22.645 21.266  58.710  1.00 21.85  ? 258 TYR F N   1 
ATOM   17765 C CA  . TYR F 1 258 ? -23.857 21.409  59.509  1.00 15.69  ? 258 TYR F CA  1 
ATOM   17766 C C   . TYR F 1 258 ? -23.516 21.380  60.995  1.00 18.69  ? 258 TYR F C   1 
ATOM   17767 O O   . TYR F 1 258 ? -22.481 20.847  61.403  1.00 19.23  ? 258 TYR F O   1 
ATOM   17768 C CB  . TYR F 1 258 ? -24.868 20.287  59.231  1.00 22.45  ? 258 TYR F CB  1 
ATOM   17769 C CG  . TYR F 1 258 ? -25.243 20.076  57.780  1.00 21.89  ? 258 TYR F CG  1 
ATOM   17770 C CD1 . TYR F 1 258 ? -24.381 19.429  56.912  1.00 21.00  ? 258 TYR F CD1 1 
ATOM   17771 C CD2 . TYR F 1 258 ? -26.465 20.505  57.291  1.00 21.16  ? 258 TYR F CD2 1 
ATOM   17772 C CE1 . TYR F 1 258 ? -24.716 19.232  55.605  1.00 23.76  ? 258 TYR F CE1 1 
ATOM   17773 C CE2 . TYR F 1 258 ? -26.808 20.320  55.960  1.00 26.12  ? 258 TYR F CE2 1 
ATOM   17774 C CZ  . TYR F 1 258 ? -25.925 19.672  55.134  1.00 21.78  ? 258 TYR F CZ  1 
ATOM   17775 O OH  . TYR F 1 258 ? -26.232 19.464  53.828  1.00 25.82  ? 258 TYR F OH  1 
ATOM   17776 N N   . HIS F 1 259 ? -24.417 21.936  61.806  1.00 19.44  ? 259 HIS F N   1 
ATOM   17777 C CA  . HIS F 1 259 ? -24.393 21.759  63.251  1.00 21.67  ? 259 HIS F CA  1 
ATOM   17778 C C   . HIS F 1 259 ? -25.615 20.972  63.701  1.00 20.20  ? 259 HIS F C   1 
ATOM   17779 O O   . HIS F 1 259 ? -26.742 21.321  63.340  1.00 19.38  ? 259 HIS F O   1 
ATOM   17780 C CB  . HIS F 1 259 ? -24.379 23.095  63.998  1.00 22.15  ? 259 HIS F CB  1 
ATOM   17781 C CG  . HIS F 1 259 ? -24.474 22.911  65.475  1.00 23.95  ? 259 HIS F CG  1 
ATOM   17782 N ND1 . HIS F 1 259 ? -25.674 22.963  66.157  1.00 20.81  ? 259 HIS F ND1 1 
ATOM   17783 C CD2 . HIS F 1 259 ? -23.529 22.588  66.391  1.00 22.76  ? 259 HIS F CD2 1 
ATOM   17784 C CE1 . HIS F 1 259 ? -25.456 22.716  67.436  1.00 26.62  ? 259 HIS F CE1 1 
ATOM   17785 N NE2 . HIS F 1 259 ? -24.163 22.487  67.605  1.00 25.22  ? 259 HIS F NE2 1 
ATOM   17786 N N   . LEU F 1 260 ? -25.402 19.950  64.533  1.00 18.72  ? 260 LEU F N   1 
ATOM   17787 C CA  . LEU F 1 260 ? -26.446 19.001  64.896  1.00 21.28  ? 260 LEU F CA  1 
ATOM   17788 C C   . LEU F 1 260 ? -26.664 18.992  66.403  1.00 24.04  ? 260 LEU F C   1 
ATOM   17789 O O   . LEU F 1 260 ? -25.706 18.814  67.157  1.00 24.89  ? 260 LEU F O   1 
ATOM   17790 C CB  . LEU F 1 260 ? -26.056 17.589  64.438  1.00 22.77  ? 260 LEU F CB  1 
ATOM   17791 C CG  . LEU F 1 260 ? -26.525 17.221  63.034  1.00 26.80  ? 260 LEU F CG  1 
ATOM   17792 C CD1 . LEU F 1 260 ? -25.971 18.204  61.951  1.00 22.69  ? 260 LEU F CD1 1 
ATOM   17793 C CD2 . LEU F 1 260 ? -26.137 15.797  62.761  1.00 21.01  ? 260 LEU F CD2 1 
ATOM   17794 N N   . ASP F 1 261 ? -27.930 19.123  66.852  1.00 26.81  ? 261 ASP F N   1 
ATOM   17795 C CA  . ASP F 1 261 ? -28.169 19.040  68.290  1.00 26.15  ? 261 ASP F CA  1 
ATOM   17796 C C   . ASP F 1 261 ? -29.439 18.315  68.716  1.00 27.38  ? 261 ASP F C   1 
ATOM   17797 O O   . ASP F 1 261 ? -29.821 18.408  69.890  1.00 36.72  ? 261 ASP F O   1 
ATOM   17798 C CB  . ASP F 1 261 ? -28.171 20.443  68.943  1.00 20.41  ? 261 ASP F CB  1 
ATOM   17799 C CG  . ASP F 1 261 ? -29.343 21.299  68.519  1.00 23.20  ? 261 ASP F CG  1 
ATOM   17800 O OD1 . ASP F 1 261 ? -30.293 20.807  67.863  1.00 26.09  ? 261 ASP F OD1 1 
ATOM   17801 O OD2 . ASP F 1 261 ? -29.294 22.509  68.820  1.00 23.00  ? 261 ASP F OD2 1 
ATOM   17802 N N   . GLY F 1 262 ? -30.134 17.602  67.865  1.00 26.76  ? 262 GLY F N   1 
ATOM   17803 C CA  . GLY F 1 262 ? -31.269 16.884  68.421  1.00 41.25  ? 262 GLY F CA  1 
ATOM   17804 C C   . GLY F 1 262 ? -32.574 17.661  68.486  1.00 35.03  ? 262 GLY F C   1 
ATOM   17805 O O   . GLY F 1 262 ? -33.640 17.052  68.666  1.00 25.60  ? 262 GLY F O   1 
ATOM   17806 N N   . ASP F 1 263 ? -32.526 18.979  68.350  1.00 30.17  ? 263 ASP F N   1 
ATOM   17807 C CA  . ASP F 1 263 ? -33.676 19.668  67.792  1.00 26.20  ? 263 ASP F CA  1 
ATOM   17808 C C   . ASP F 1 263 ? -33.620 19.683  66.258  1.00 30.42  ? 263 ASP F C   1 
ATOM   17809 O O   . ASP F 1 263 ? -34.652 19.515  65.603  1.00 29.38  ? 263 ASP F O   1 
ATOM   17810 C CB  . ASP F 1 263 ? -33.751 21.099  68.333  1.00 31.02  ? 263 ASP F CB  1 
ATOM   17811 C CG  . ASP F 1 263 ? -34.342 21.170  69.735  1.00 36.86  ? 263 ASP F CG  1 
ATOM   17812 O OD1 . ASP F 1 263 ? -35.008 20.209  70.178  1.00 35.74  ? 263 ASP F OD1 1 
ATOM   17813 O OD2 . ASP F 1 263 ? -34.125 22.193  70.410  1.00 44.45  ? 263 ASP F OD2 1 
ATOM   17814 N N   . ARG F 1 264 ? -32.429 19.837  65.672  1.00 23.96  ? 264 ARG F N   1 
ATOM   17815 C CA  . ARG F 1 264 ? -32.306 20.187  64.260  1.00 22.72  ? 264 ARG F CA  1 
ATOM   17816 C C   . ARG F 1 264 ? -30.913 19.856  63.718  1.00 26.40  ? 264 ARG F C   1 
ATOM   17817 O O   . ARG F 1 264 ? -29.925 19.775  64.456  1.00 22.81  ? 264 ARG F O   1 
ATOM   17818 C CB  . ARG F 1 264 ? -32.591 21.672  64.077  1.00 24.80  ? 264 ARG F CB  1 
ATOM   17819 C CG  . ARG F 1 264 ? -31.948 22.459  65.235  1.00 30.75  ? 264 ARG F CG  1 
ATOM   17820 C CD  . ARG F 1 264 ? -31.307 23.702  64.765  1.00 32.47  ? 264 ARG F CD  1 
ATOM   17821 N NE  . ARG F 1 264 ? -30.276 24.236  65.647  1.00 29.01  ? 264 ARG F NE  1 
ATOM   17822 C CZ  . ARG F 1 264 ? -29.049 23.749  65.780  1.00 29.74  ? 264 ARG F CZ  1 
ATOM   17823 N NH1 . ARG F 1 264 ? -28.711 22.562  65.297  1.00 24.69  ? 264 ARG F NH1 1 
ATOM   17824 N NH2 . ARG F 1 264 ? -28.128 24.490  66.377  1.00 28.41  ? 264 ARG F NH2 1 
ATOM   17825 N N   . ALA F 1 265 ? -30.851 19.675  62.409  1.00 25.99  ? 265 ALA F N   1 
ATOM   17826 C CA  . ALA F 1 265 ? -29.597 19.725  61.666  1.00 30.03  ? 265 ALA F CA  1 
ATOM   17827 C C   . ALA F 1 265 ? -29.597 21.041  60.895  1.00 26.02  ? 265 ALA F C   1 
ATOM   17828 O O   . ALA F 1 265 ? -30.381 21.215  59.957  1.00 29.19  ? 265 ALA F O   1 
ATOM   17829 C CB  . ALA F 1 265 ? -29.449 18.530  60.722  1.00 29.40  ? 265 ALA F CB  1 
ATOM   17830 N N   . ARG F 1 266 ? -28.726 21.964  61.276  1.00 20.61  ? 266 ARG F N   1 
ATOM   17831 C CA  . ARG F 1 266 ? -28.749 23.299  60.693  1.00 25.42  ? 266 ARG F CA  1 
ATOM   17832 C C   . ARG F 1 266 ? -27.614 23.432  59.683  1.00 23.68  ? 266 ARG F C   1 
ATOM   17833 O O   . ARG F 1 266 ? -26.446 23.195  60.021  1.00 16.90  ? 266 ARG F O   1 
ATOM   17834 C CB  . ARG F 1 266 ? -28.653 24.376  61.773  1.00 26.93  ? 266 ARG F CB  1 
ATOM   17835 C CG  . ARG F 1 266 ? -28.407 25.796  61.219  1.00 22.96  ? 266 ARG F CG  1 
ATOM   17836 C CD  . ARG F 1 266 ? -29.178 26.818  62.012  1.00 35.50  ? 266 ARG F CD  1 
ATOM   17837 N NE  . ARG F 1 266 ? -28.421 27.349  63.138  1.00 40.17  ? 266 ARG F NE  1 
ATOM   17838 C CZ  . ARG F 1 266 ? -28.947 28.141  64.065  1.00 50.73  ? 266 ARG F CZ  1 
ATOM   17839 N NH1 . ARG F 1 266 ? -30.236 28.460  64.050  1.00 41.01  ? 266 ARG F NH1 1 
ATOM   17840 N NH2 . ARG F 1 266 ? -28.162 28.627  65.029  1.00 48.75  ? 266 ARG F NH2 1 
ATOM   17841 N N   . PHE F 1 267 ? -27.971 23.795  58.450  1.00 19.51  ? 267 PHE F N   1 
ATOM   17842 C CA  . PHE F 1 267 ? -26.989 24.075  57.409  1.00 22.67  ? 267 PHE F CA  1 
ATOM   17843 C C   . PHE F 1 267 ? -26.221 25.340  57.758  1.00 22.78  ? 267 PHE F C   1 
ATOM   17844 O O   . PHE F 1 267 ? -26.820 26.378  58.048  1.00 23.96  ? 267 PHE F O   1 
ATOM   17845 C CB  . PHE F 1 267 ? -27.688 24.243  56.056  1.00 20.36  ? 267 PHE F CB  1 
ATOM   17846 C CG  . PHE F 1 267 ? -26.752 24.518  54.901  1.00 28.77  ? 267 PHE F CG  1 
ATOM   17847 C CD1 . PHE F 1 267 ? -26.303 25.802  54.636  1.00 29.81  ? 267 PHE F CD1 1 
ATOM   17848 C CD2 . PHE F 1 267 ? -26.370 23.499  54.038  1.00 29.23  ? 267 PHE F CD2 1 
ATOM   17849 C CE1 . PHE F 1 267 ? -25.456 26.053  53.554  1.00 28.91  ? 267 PHE F CE1 1 
ATOM   17850 C CE2 . PHE F 1 267 ? -25.526 23.757  52.949  1.00 30.68  ? 267 PHE F CE2 1 
ATOM   17851 C CZ  . PHE F 1 267 ? -25.069 25.028  52.721  1.00 27.78  ? 267 PHE F CZ  1 
ATOM   17852 N N   . LEU F 1 268 ? -24.892 25.254  57.736  1.00 22.94  ? 268 LEU F N   1 
ATOM   17853 C CA  . LEU F 1 268 ? -24.045 26.407  58.022  1.00 22.68  ? 268 LEU F CA  1 
ATOM   17854 C C   . LEU F 1 268 ? -23.545 27.080  56.745  1.00 23.77  ? 268 LEU F C   1 
ATOM   17855 O O   . LEU F 1 268 ? -23.818 28.262  56.514  1.00 22.26  ? 268 LEU F O   1 
ATOM   17856 C CB  . LEU F 1 268 ? -22.872 25.972  58.907  1.00 18.94  ? 268 LEU F CB  1 
ATOM   17857 C CG  . LEU F 1 268 ? -23.302 25.286  60.204  1.00 20.58  ? 268 LEU F CG  1 
ATOM   17858 C CD1 . LEU F 1 268 ? -22.069 24.830  60.973  1.00 19.30  ? 268 LEU F CD1 1 
ATOM   17859 C CD2 . LEU F 1 268 ? -24.210 26.208  61.080  1.00 21.45  ? 268 LEU F CD2 1 
ATOM   17860 N N   . HIS F 1 269 ? -22.828 26.344  55.899  1.00 18.56  ? 269 HIS F N   1 
ATOM   17861 C CA  . HIS F 1 269 ? -22.244 26.932  54.708  1.00 19.37  ? 269 HIS F CA  1 
ATOM   17862 C C   . HIS F 1 269 ? -21.885 25.825  53.739  1.00 24.39  ? 269 HIS F C   1 
ATOM   17863 O O   . HIS F 1 269 ? -21.812 24.652  54.112  1.00 20.56  ? 269 HIS F O   1 
ATOM   17864 C CB  . HIS F 1 269 ? -20.991 27.743  55.042  1.00 21.43  ? 269 HIS F CB  1 
ATOM   17865 C CG  . HIS F 1 269 ? -19.847 26.894  55.511  1.00 20.74  ? 269 HIS F CG  1 
ATOM   17866 N ND1 . HIS F 1 269 ? -18.910 26.359  54.651  1.00 24.04  ? 269 HIS F ND1 1 
ATOM   17867 C CD2 . HIS F 1 269 ? -19.510 26.466  56.749  1.00 19.81  ? 269 HIS F CD2 1 
ATOM   17868 C CE1 . HIS F 1 269 ? -18.035 25.654  55.347  1.00 24.34  ? 269 HIS F CE1 1 
ATOM   17869 N NE2 . HIS F 1 269 ? -18.386 25.690  56.620  1.00 21.03  ? 269 HIS F NE2 1 
ATOM   17870 N N   . SER F 1 270 ? -21.664 26.221  52.482  1.00 23.90  ? 270 SER F N   1 
ATOM   17871 C CA  . SER F 1 270 ? -21.047 25.374  51.475  1.00 24.04  ? 270 SER F CA  1 
ATOM   17872 C C   . SER F 1 270 ? -19.731 26.015  51.080  1.00 29.90  ? 270 SER F C   1 
ATOM   17873 O O   . SER F 1 270 ? -19.614 27.244  51.050  1.00 31.48  ? 270 SER F O   1 
ATOM   17874 C CB  . SER F 1 270 ? -21.940 25.192  50.232  1.00 25.87  ? 270 SER F CB  1 
ATOM   17875 O OG  . SER F 1 270 ? -21.972 26.368  49.430  1.00 28.22  ? 270 SER F OG  1 
ATOM   17876 N N   . SER F 1 271 ? -18.739 25.183  50.790  1.00 27.68  ? 271 SER F N   1 
ATOM   17877 C CA  . SER F 1 271 ? -17.418 25.678  50.457  1.00 29.11  ? 271 SER F CA  1 
ATOM   17878 C C   . SER F 1 271 ? -16.820 24.833  49.349  1.00 28.68  ? 271 SER F C   1 
ATOM   17879 O O   . SER F 1 271 ? -17.192 23.677  49.160  1.00 26.94  ? 271 SER F O   1 
ATOM   17880 C CB  . SER F 1 271 ? -16.520 25.713  51.696  1.00 28.75  ? 271 SER F CB  1 
ATOM   17881 O OG  . SER F 1 271 ? -16.895 26.834  52.492  1.00 29.35  ? 271 SER F OG  1 
ATOM   17882 N N   . ILE F 1 272 ? -15.901 25.440  48.597  1.00 32.06  ? 272 ILE F N   1 
ATOM   17883 C CA  . ILE F 1 272 ? -15.201 24.782  47.496  1.00 31.38  ? 272 ILE F CA  1 
ATOM   17884 C C   . ILE F 1 272 ? -13.752 24.554  47.904  1.00 38.35  ? 272 ILE F C   1 
ATOM   17885 O O   . ILE F 1 272 ? -13.013 25.518  48.130  1.00 35.33  ? 272 ILE F O   1 
ATOM   17886 C CB  . ILE F 1 272 ? -15.248 25.614  46.209  1.00 33.51  ? 272 ILE F CB  1 
ATOM   17887 C CG1 . ILE F 1 272 ? -16.677 25.867  45.761  1.00 36.02  ? 272 ILE F CG1 1 
ATOM   17888 C CG2 . ILE F 1 272 ? -14.507 24.900  45.106  1.00 35.96  ? 272 ILE F CG2 1 
ATOM   17889 C CD1 . ILE F 1 272 ? -16.775 26.976  44.728  1.00 39.93  ? 272 ILE F CD1 1 
ATOM   17890 N N   . LEU F 1 273 ? -13.324 23.295  47.950  1.00 30.15  ? 273 LEU F N   1 
ATOM   17891 C CA  . LEU F 1 273 ? -11.902 23.023  48.118  1.00 36.79  ? 273 LEU F CA  1 
ATOM   17892 C C   . LEU F 1 273 ? -11.165 23.379  46.831  1.00 35.09  ? 273 LEU F C   1 
ATOM   17893 O O   . LEU F 1 273 ? -11.575 22.987  45.735  1.00 36.10  ? 273 LEU F O   1 
ATOM   17894 C CB  . LEU F 1 273 ? -11.667 21.556  48.488  1.00 38.96  ? 273 LEU F CB  1 
ATOM   17895 C CG  . LEU F 1 273 ? -12.197 21.127  49.862  1.00 30.44  ? 273 LEU F CG  1 
ATOM   17896 C CD1 . LEU F 1 273 ? -13.412 20.263  49.635  1.00 36.07  ? 273 LEU F CD1 1 
ATOM   17897 C CD2 . LEU F 1 273 ? -11.151 20.369  50.634  1.00 39.46  ? 273 LEU F CD2 1 
ATOM   17898 N N   . LYS F 1 274 ? -10.088 24.135  46.959  1.00 33.34  ? 274 LYS F N   1 
ATOM   17899 C CA  . LYS F 1 274 ? -9.343  24.622  45.809  1.00 35.86  ? 274 LYS F CA  1 
ATOM   17900 C C   . LYS F 1 274 ? -8.024  23.876  45.679  1.00 40.19  ? 274 LYS F C   1 
ATOM   17901 O O   . LYS F 1 274 ? -7.330  23.627  46.672  1.00 41.46  ? 274 LYS F O   1 
ATOM   17902 C CB  . LYS F 1 274 ? -9.087  26.124  45.916  1.00 32.95  ? 274 LYS F CB  1 
ATOM   17903 C CG  . LYS F 1 274 ? -10.334 26.954  45.653  1.00 35.52  ? 274 LYS F CG  1 
ATOM   17904 C CD  . LYS F 1 274 ? -11.067 26.463  44.397  1.00 44.17  ? 274 LYS F CD  1 
ATOM   17905 C CE  . LYS F 1 274 ? -10.543 27.152  43.128  1.00 35.82  ? 274 LYS F CE  1 
ATOM   17906 N NZ  . LYS F 1 274 ? -10.221 28.594  43.432  1.00 41.49  ? 274 LYS F NZ  1 
ATOM   17907 N N   . TYR F 1 275 ? -7.676  23.534  44.446  1.00 44.31  ? 275 TYR F N   1 
ATOM   17908 C CA  . TYR F 1 275 ? -6.499  22.730  44.169  1.00 47.10  ? 275 TYR F CA  1 
ATOM   17909 C C   . TYR F 1 275 ? -5.670  23.359  43.060  1.00 49.72  ? 275 TYR F C   1 
ATOM   17910 O O   . TYR F 1 275 ? -6.155  24.200  42.297  1.00 49.72  ? 275 TYR F O   1 
ATOM   17911 C CB  . TYR F 1 275 ? -6.899  21.326  43.742  1.00 43.91  ? 275 TYR F CB  1 
ATOM   17912 C CG  . TYR F 1 275 ? -7.557  20.501  44.810  1.00 37.55  ? 275 TYR F CG  1 
ATOM   17913 C CD1 . TYR F 1 275 ? -6.803  19.765  45.698  1.00 35.23  ? 275 TYR F CD1 1 
ATOM   17914 C CD2 . TYR F 1 275 ? -8.935  20.441  44.911  1.00 38.73  ? 275 TYR F CD2 1 
ATOM   17915 C CE1 . TYR F 1 275 ? -7.397  18.988  46.659  1.00 38.02  ? 275 TYR F CE1 1 
ATOM   17916 C CE2 . TYR F 1 275 ? -9.540  19.672  45.875  1.00 39.29  ? 275 TYR F CE2 1 
ATOM   17917 C CZ  . TYR F 1 275 ? -8.764  18.946  46.746  1.00 37.03  ? 275 TYR F CZ  1 
ATOM   17918 O OH  . TYR F 1 275 ? -9.357  18.174  47.714  1.00 41.11  ? 275 TYR F OH  1 
ATOM   17919 N N   . GLU F 1 276 ? -4.393  22.960  43.019  1.00 53.63  ? 276 GLU F N   1 
ATOM   17920 C CA  . GLU F 1 276 ? -3.582  22.952  41.801  1.00 57.27  ? 276 GLU F CA  1 
ATOM   17921 C C   . GLU F 1 276 ? -2.192  22.398  42.084  1.00 63.96  ? 276 GLU F C   1 
ATOM   17922 O O   . GLU F 1 276 ? -1.633  22.636  43.161  1.00 61.48  ? 276 GLU F O   1 
ATOM   17923 C CB  . GLU F 1 276 ? -3.465  24.332  41.164  1.00 55.01  ? 276 GLU F CB  1 
ATOM   17924 C CG  . GLU F 1 276 ? -4.167  24.386  39.820  1.00 52.69  ? 276 GLU F CG  1 
ATOM   17925 C CD  . GLU F 1 276 ? -3.208  24.589  38.681  1.00 62.44  ? 276 GLU F CD  1 
ATOM   17926 O OE1 . GLU F 1 276 ? -2.864  25.759  38.411  1.00 63.07  ? 276 GLU F OE1 1 
ATOM   17927 O OE2 . GLU F 1 276 ? -2.796  23.586  38.060  1.00 60.16  ? 276 GLU F OE2 1 
ATOM   17928 N N   . GLN F 1 277 ? -1.639  21.686  41.093  1.00 68.14  ? 277 GLN F N   1 
ATOM   17929 C CA  . GLN F 1 277 ? -0.406  20.878  41.176  1.00 66.16  ? 277 GLN F CA  1 
ATOM   17930 C C   . GLN F 1 277 ? 0.642   21.407  42.156  1.00 60.15  ? 277 GLN F C   1 
ATOM   17931 O O   . GLN F 1 277 ? 0.614   21.068  43.342  1.00 58.44  ? 277 GLN F O   1 
ATOM   17932 C CB  . GLN F 1 277 ? 0.225   20.747  39.775  1.00 59.46  ? 277 GLN F CB  1 
ATOM   17933 C CG  . GLN F 1 277 ? -0.665  20.077  38.719  1.00 54.38  ? 277 GLN F CG  1 
ATOM   17934 C CD  . GLN F 1 277 ? -1.359  21.091  37.807  1.00 67.45  ? 277 GLN F CD  1 
ATOM   17935 O OE1 . GLN F 1 277 ? -0.715  21.956  37.205  1.00 62.54  ? 277 GLN F OE1 1 
ATOM   17936 N NE2 . GLN F 1 277 ? -2.684  20.990  37.711  1.00 67.21  ? 277 GLN F NE2 1 
ATOM   17937 N N   . GLY F 1 284 ? -0.604  12.947  38.372  1.00 35.56  ? 284 GLY F N   1 
ATOM   17938 C CA  . GLY F 1 284 ? -0.896  14.316  38.741  1.00 41.16  ? 284 GLY F CA  1 
ATOM   17939 C C   . GLY F 1 284 ? -1.694  14.437  40.031  1.00 37.41  ? 284 GLY F C   1 
ATOM   17940 O O   . GLY F 1 284 ? -2.895  14.218  40.030  1.00 39.78  ? 284 GLY F O   1 
ATOM   17941 N N   . SER F 1 285 ? -1.024  14.797  41.129  1.00 40.06  ? 285 SER F N   1 
ATOM   17942 C CA  . SER F 1 285 ? -1.654  15.043  42.428  1.00 37.72  ? 285 SER F CA  1 
ATOM   17943 C C   . SER F 1 285 ? -1.566  16.530  42.745  1.00 38.86  ? 285 SER F C   1 
ATOM   17944 O O   . SER F 1 285 ? -0.516  17.014  43.173  1.00 43.50  ? 285 SER F O   1 
ATOM   17945 C CB  . SER F 1 285 ? -0.970  14.236  43.525  1.00 35.10  ? 285 SER F CB  1 
ATOM   17946 O OG  . SER F 1 285 ? -1.568  12.966  43.681  1.00 39.17  ? 285 SER F OG  1 
ATOM   17947 N N   . ALA F 1 286 ? -2.674  17.247  42.588  1.00 44.95  ? 286 ALA F N   1 
ATOM   17948 C CA  . ALA F 1 286 ? -2.681  18.679  42.861  1.00 44.40  ? 286 ALA F CA  1 
ATOM   17949 C C   . ALA F 1 286 ? -2.739  18.949  44.364  1.00 42.95  ? 286 ALA F C   1 
ATOM   17950 O O   . ALA F 1 286 ? -3.556  18.368  45.083  1.00 37.18  ? 286 ALA F O   1 
ATOM   17951 C CB  . ALA F 1 286 ? -3.858  19.348  42.152  1.00 48.85  ? 286 ALA F CB  1 
ATOM   17952 N N   . LYS F 1 287 ? -1.866  19.836  44.830  1.00 45.05  ? 287 LYS F N   1 
ATOM   17953 C CA  . LYS F 1 287 ? -1.842  20.249  46.228  1.00 44.66  ? 287 LYS F CA  1 
ATOM   17954 C C   . LYS F 1 287 ? -3.112  21.022  46.590  1.00 41.36  ? 287 LYS F C   1 
ATOM   17955 O O   . LYS F 1 287 ? -3.707  21.701  45.749  1.00 40.84  ? 287 LYS F O   1 
ATOM   17956 C CB  . LYS F 1 287 ? -0.601  21.118  46.460  1.00 51.06  ? 287 LYS F CB  1 
ATOM   17957 C CG  . LYS F 1 287 ? -0.299  21.517  47.891  1.00 51.12  ? 287 LYS F CG  1 
ATOM   17958 C CD  . LYS F 1 287 ? 0.446   22.850  47.906  1.00 54.03  ? 287 LYS F CD  1 
ATOM   17959 C CE  . LYS F 1 287 ? 1.879   22.700  48.380  1.00 49.60  ? 287 LYS F CE  1 
ATOM   17960 N NZ  . LYS F 1 287 ? 1.969   22.969  49.834  1.00 49.10  ? 287 LYS F NZ  1 
ATOM   17961 N N   . TRP F 1 288 ? -3.522  20.924  47.865  1.00 45.21  ? 288 TRP F N   1 
ATOM   17962 C CA  . TRP F 1 288 ? -4.658  21.689  48.393  1.00 43.84  ? 288 TRP F CA  1 
ATOM   17963 C C   . TRP F 1 288 ? -4.209  23.095  48.786  1.00 38.09  ? 288 TRP F C   1 
ATOM   17964 O O   . TRP F 1 288 ? -3.340  23.250  49.648  1.00 43.03  ? 288 TRP F O   1 
ATOM   17965 C CB  . TRP F 1 288 ? -5.271  20.981  49.600  1.00 36.64  ? 288 TRP F CB  1 
ATOM   17966 C CG  . TRP F 1 288 ? -6.358  21.787  50.288  1.00 38.96  ? 288 TRP F CG  1 
ATOM   17967 C CD1 . TRP F 1 288 ? -7.476  22.309  49.709  1.00 39.11  ? 288 TRP F CD1 1 
ATOM   17968 C CD2 . TRP F 1 288 ? -6.428  22.139  51.682  1.00 31.50  ? 288 TRP F CD2 1 
ATOM   17969 N NE1 . TRP F 1 288 ? -8.228  22.973  50.648  1.00 36.44  ? 288 TRP F NE1 1 
ATOM   17970 C CE2 . TRP F 1 288 ? -7.607  22.882  51.866  1.00 34.43  ? 288 TRP F CE2 1 
ATOM   17971 C CE3 . TRP F 1 288 ? -5.595  21.909  52.788  1.00 36.56  ? 288 TRP F CE3 1 
ATOM   17972 C CZ2 . TRP F 1 288 ? -7.988  23.393  53.114  1.00 33.11  ? 288 TRP F CZ2 1 
ATOM   17973 C CZ3 . TRP F 1 288 ? -5.969  22.423  54.027  1.00 39.18  ? 288 TRP F CZ3 1 
ATOM   17974 C CH2 . TRP F 1 288 ? -7.160  23.156  54.179  1.00 32.61  ? 288 TRP F CH2 1 
ATOM   17975 N N   . ILE F 1 289 ? -4.819  24.124  48.192  1.00 38.44  ? 289 ILE F N   1 
ATOM   17976 C CA  . ILE F 1 289 ? -4.308  25.477  48.363  1.00 37.10  ? 289 ILE F CA  1 
ATOM   17977 C C   . ILE F 1 289 ? -5.351  26.456  48.917  1.00 42.67  ? 289 ILE F C   1 
ATOM   17978 O O   . ILE F 1 289 ? -5.136  27.673  48.865  1.00 46.29  ? 289 ILE F O   1 
ATOM   17979 C CB  . ILE F 1 289 ? -3.694  26.000  47.048  1.00 44.56  ? 289 ILE F CB  1 
ATOM   17980 C CG1 . ILE F 1 289 ? -4.770  26.258  45.992  1.00 38.07  ? 289 ILE F CG1 1 
ATOM   17981 C CG2 . ILE F 1 289 ? -2.625  25.001  46.536  1.00 41.41  ? 289 ILE F CG2 1 
ATOM   17982 C CD1 . ILE F 1 289 ? -4.300  25.983  44.580  1.00 45.69  ? 289 ILE F CD1 1 
ATOM   17983 N N   . GLY F 1 290 ? -6.462  25.962  49.486  1.00 37.18  ? 290 GLY F N   1 
ATOM   17984 C CA  . GLY F 1 290 ? -7.399  26.807  50.208  1.00 34.68  ? 290 GLY F CA  1 
ATOM   17985 C C   . GLY F 1 290 ? -8.830  26.407  49.914  1.00 33.05  ? 290 GLY F C   1 
ATOM   17986 O O   . GLY F 1 290 ? -9.086  25.304  49.440  1.00 34.03  ? 290 GLY F O   1 
ATOM   17987 N N   . LEU F 1 291 ? -9.771  27.314  50.207  1.00 33.52  ? 291 LEU F N   1 
ATOM   17988 C CA  . LEU F 1 291 ? -11.157 27.118  49.794  1.00 39.27  ? 291 LEU F CA  1 
ATOM   17989 C C   . LEU F 1 291 ? -11.869 28.463  49.610  1.00 33.76  ? 291 LEU F C   1 
ATOM   17990 O O   . LEU F 1 291 ? -11.474 29.472  50.197  1.00 33.24  ? 291 LEU F O   1 
ATOM   17991 C CB  . LEU F 1 291 ? -11.882 26.196  50.783  1.00 37.90  ? 291 LEU F CB  1 
ATOM   17992 C CG  . LEU F 1 291 ? -11.947 26.533  52.254  1.00 34.90  ? 291 LEU F CG  1 
ATOM   17993 C CD1 . LEU F 1 291 ? -13.148 27.420  52.448  1.00 34.51  ? 291 LEU F CD1 1 
ATOM   17994 C CD2 . LEU F 1 291 ? -12.065 25.260  53.077  1.00 27.30  ? 291 LEU F CD2 1 
ATOM   17995 N N   . ASP F 1 292 ? -12.914 28.473  48.771  1.00 34.93  ? 292 ASP F N   1 
ATOM   17996 C CA  . ASP F 1 292 ? -13.580 29.709  48.350  1.00 35.34  ? 292 ASP F CA  1 
ATOM   17997 C C   . ASP F 1 292 ? -15.002 29.873  48.886  1.00 41.14  ? 292 ASP F C   1 
ATOM   17998 O O   . ASP F 1 292 ? -15.641 30.892  48.609  1.00 45.23  ? 292 ASP F O   1 
ATOM   17999 C CB  . ASP F 1 292 ? -13.625 29.808  46.816  1.00 36.46  ? 292 ASP F CB  1 
ATOM   18000 C CG  . ASP F 1 292 ? -12.242 29.943  46.180  1.00 38.28  ? 292 ASP F CG  1 
ATOM   18001 O OD1 . ASP F 1 292 ? -11.247 30.180  46.906  1.00 29.18  ? 292 ASP F OD1 1 
ATOM   18002 O OD2 . ASP F 1 292 ? -12.165 29.818  44.936  1.00 38.31  ? 292 ASP F OD2 1 
ATOM   18003 N N   . SER F 1 293 ? -15.526 28.902  49.603  1.00 37.71  ? 293 SER F N   1 
ATOM   18004 C CA  . SER F 1 293 ? -16.809 28.982  50.311  1.00 41.74  ? 293 SER F CA  1 
ATOM   18005 C C   . SER F 1 293 ? -18.032 29.036  49.399  1.00 47.73  ? 293 SER F C   1 
ATOM   18006 O O   . SER F 1 293 ? -18.315 27.981  48.822  1.00 47.29  ? 293 SER F O   1 
ATOM   18007 C CB  . SER F 1 293 ? -16.877 30.117  51.307  1.00 34.89  ? 293 SER F CB  1 
ATOM   18008 O OG  . SER F 1 293 ? -18.107 29.964  52.007  1.00 35.77  ? 293 SER F OG  1 
ATOM   18009 N N   . PRO F 1 294 ? -18.868 30.196  49.266  1.00 40.85  ? 294 PRO F N   1 
ATOM   18010 C CA  . PRO F 1 294 ? -20.188 29.988  48.662  1.00 35.38  ? 294 PRO F CA  1 
ATOM   18011 C C   . PRO F 1 294 ? -19.904 29.185  47.416  1.00 40.08  ? 294 PRO F C   1 
ATOM   18012 O O   . PRO F 1 294 ? -19.117 29.613  46.567  1.00 37.77  ? 294 PRO F O   1 
ATOM   18013 C CB  . PRO F 1 294 ? -20.725 31.394  48.365  1.00 36.32  ? 294 PRO F CB  1 
ATOM   18014 C CG  . PRO F 1 294 ? -19.730 32.323  48.813  1.00 33.77  ? 294 PRO F CG  1 
ATOM   18015 C CD  . PRO F 1 294 ? -18.456 31.606  49.094  1.00 31.91  ? 294 PRO F CD  1 
ATOM   18016 N N   . SER F 1 295 ? -20.395 27.950  47.411  1.00 36.88  ? 295 SER F N   1 
ATOM   18017 C CA  . SER F 1 295 ? -19.822 26.877  46.614  1.00 36.58  ? 295 SER F CA  1 
ATOM   18018 C C   . SER F 1 295 ? -20.312 26.816  45.186  1.00 37.60  ? 295 SER F C   1 
ATOM   18019 O O   . SER F 1 295 ? -19.818 25.970  44.438  1.00 48.03  ? 295 SER F O   1 
ATOM   18020 C CB  . SER F 1 295 ? -20.110 25.517  47.249  1.00 29.14  ? 295 SER F CB  1 
ATOM   18021 O OG  . SER F 1 295 ? -21.478 25.174  47.004  1.00 34.39  ? 295 SER F OG  1 
ATOM   18022 N N   . ARG F 1 296 ? -21.273 27.624  44.777  1.00 32.56  ? 296 ARG F N   1 
ATOM   18023 C CA  . ARG F 1 296 ? -21.794 27.487  43.413  1.00 38.73  ? 296 ARG F CA  1 
ATOM   18024 C C   . ARG F 1 296 ? -22.391 26.107  43.164  1.00 30.30  ? 296 ARG F C   1 
ATOM   18025 O O   . ARG F 1 296 ? -22.570 25.707  42.011  1.00 33.06  ? 296 ARG F O   1 
ATOM   18026 C CB  . ARG F 1 296 ? -20.721 27.767  42.343  1.00 34.88  ? 296 ARG F CB  1 
ATOM   18027 C CG  . ARG F 1 296 ? -19.916 29.039  42.550  1.00 46.16  ? 296 ARG F CG  1 
ATOM   18028 C CD  . ARG F 1 296 ? -18.632 29.073  41.712  1.00 45.73  ? 296 ARG F CD  1 
ATOM   18029 N NE  . ARG F 1 296 ? -17.462 29.475  42.491  1.00 56.12  ? 296 ARG F NE  1 
ATOM   18030 C CZ  . ARG F 1 296 ? -17.250 30.690  42.991  1.00 57.35  ? 296 ARG F CZ  1 
ATOM   18031 N NH1 . ARG F 1 296 ? -18.118 31.679  42.812  1.00 46.19  ? 296 ARG F NH1 1 
ATOM   18032 N NH2 . ARG F 1 296 ? -16.139 30.917  43.696  1.00 48.33  ? 296 ARG F NH2 1 
ATOM   18033 N N   . SER F 1 297 ? -22.687 25.363  44.233  1.00 32.92  ? 297 SER F N   1 
ATOM   18034 C CA  . SER F 1 297 ? -23.174 23.991  44.142  1.00 32.26  ? 297 SER F CA  1 
ATOM   18035 C C   . SER F 1 297 ? -24.383 23.764  45.045  1.00 33.59  ? 297 SER F C   1 
ATOM   18036 O O   . SER F 1 297 ? -24.688 22.622  45.395  1.00 32.83  ? 297 SER F O   1 
ATOM   18037 C CB  . SER F 1 297 ? -22.063 22.998  44.496  1.00 29.70  ? 297 SER F CB  1 
ATOM   18038 O OG  . SER F 1 297 ? -21.137 22.818  43.429  1.00 31.50  ? 297 SER F OG  1 
ATOM   18039 N N   . GLU F 1 298 ? -25.071 24.827  45.442  1.00 31.01  ? 298 GLU F N   1 
ATOM   18040 C CA  . GLU F 1 298 ? -26.221 24.721  46.331  1.00 34.22  ? 298 GLU F CA  1 
ATOM   18041 C C   . GLU F 1 298 ? -27.481 24.670  45.474  1.00 34.39  ? 298 GLU F C   1 
ATOM   18042 O O   . GLU F 1 298 ? -27.978 25.700  45.017  1.00 39.13  ? 298 GLU F O   1 
ATOM   18043 C CB  . GLU F 1 298 ? -26.256 25.894  47.298  1.00 33.79  ? 298 GLU F CB  1 
ATOM   18044 C CG  . GLU F 1 298 ? -25.110 25.920  48.289  1.00 31.64  ? 298 GLU F CG  1 
ATOM   18045 C CD  . GLU F 1 298 ? -25.146 27.198  49.123  1.00 38.66  ? 298 GLU F CD  1 
ATOM   18046 O OE1 . GLU F 1 298 ? -26.241 27.792  49.235  1.00 43.95  ? 298 GLU F OE1 1 
ATOM   18047 O OE2 . GLU F 1 298 ? -24.093 27.620  49.655  1.00 38.47  ? 298 GLU F OE2 1 
ATOM   18048 N N   . PHE F 1 299 ? -27.989 23.466  45.239  1.00 32.42  ? 299 PHE F N   1 
ATOM   18049 C CA  . PHE F 1 299 ? -29.241 23.294  44.514  1.00 37.57  ? 299 PHE F CA  1 
ATOM   18050 C C   . PHE F 1 299 ? -29.844 21.968  44.952  1.00 35.56  ? 299 PHE F C   1 
ATOM   18051 O O   . PHE F 1 299 ? -29.193 21.161  45.625  1.00 33.11  ? 299 PHE F O   1 
ATOM   18052 C CB  . PHE F 1 299 ? -29.047 23.364  42.986  1.00 34.12  ? 299 PHE F CB  1 
ATOM   18053 C CG  . PHE F 1 299 ? -27.908 22.518  42.467  1.00 36.28  ? 299 PHE F CG  1 
ATOM   18054 C CD1 . PHE F 1 299 ? -28.120 21.204  42.067  1.00 34.28  ? 299 PHE F CD1 1 
ATOM   18055 C CD2 . PHE F 1 299 ? -26.627 23.040  42.374  1.00 34.26  ? 299 PHE F CD2 1 
ATOM   18056 C CE1 . PHE F 1 299 ? -27.069 20.423  41.579  1.00 34.69  ? 299 PHE F CE1 1 
ATOM   18057 C CE2 . PHE F 1 299 ? -25.568 22.264  41.891  1.00 39.68  ? 299 PHE F CE2 1 
ATOM   18058 C CZ  . PHE F 1 299 ? -25.793 20.952  41.498  1.00 34.88  ? 299 PHE F CZ  1 
ATOM   18059 N N   . GLU F 1 300 ? -31.105 21.752  44.562  1.00 35.35  ? 300 GLU F N   1 
ATOM   18060 C CA  . GLU F 1 300 ? -31.882 20.658  45.136  1.00 36.33  ? 300 GLU F CA  1 
ATOM   18061 C C   . GLU F 1 300 ? -31.164 19.324  44.987  1.00 32.97  ? 300 GLU F C   1 
ATOM   18062 O O   . GLU F 1 300 ? -31.157 18.507  45.918  1.00 27.92  ? 300 GLU F O   1 
ATOM   18063 C CB  . GLU F 1 300 ? -33.269 20.603  44.492  1.00 42.04  ? 300 GLU F CB  1 
ATOM   18064 C CG  . GLU F 1 300 ? -34.389 20.092  45.433  1.00 49.26  ? 300 GLU F CG  1 
ATOM   18065 C CD  . GLU F 1 300 ? -34.887 21.147  46.441  1.00 57.51  ? 300 GLU F CD  1 
ATOM   18066 O OE1 . GLU F 1 300 ? -34.079 21.988  46.922  1.00 52.90  ? 300 GLU F OE1 1 
ATOM   18067 O OE2 . GLU F 1 300 ? -36.107 21.136  46.733  1.00 55.02  ? 300 GLU F OE2 1 
ATOM   18068 N N   . ALA F 1 301 ? -30.515 19.110  43.839  1.00 31.74  ? 301 ALA F N   1 
ATOM   18069 C CA  . ALA F 1 301 ? -29.886 17.829  43.533  1.00 30.08  ? 301 ALA F CA  1 
ATOM   18070 C C   . ALA F 1 301 ? -28.709 17.518  44.444  1.00 29.44  ? 301 ALA F C   1 
ATOM   18071 O O   . ALA F 1 301 ? -28.311 16.354  44.540  1.00 27.35  ? 301 ALA F O   1 
ATOM   18072 C CB  . ALA F 1 301 ? -29.416 17.803  42.077  1.00 31.45  ? 301 ALA F CB  1 
ATOM   18073 N N   . THR F 1 302 ? -28.116 18.527  45.078  1.00 27.36  ? 302 THR F N   1 
ATOM   18074 C CA  . THR F 1 302 ? -27.085 18.299  46.077  1.00 24.60  ? 302 THR F CA  1 
ATOM   18075 C C   . THR F 1 302 ? -27.627 18.438  47.499  1.00 26.07  ? 302 THR F C   1 
ATOM   18076 O O   . THR F 1 302 ? -27.422 17.552  48.330  1.00 23.75  ? 302 THR F O   1 
ATOM   18077 C CB  . THR F 1 302 ? -25.918 19.267  45.848  1.00 29.93  ? 302 THR F CB  1 
ATOM   18078 O OG1 . THR F 1 302 ? -26.397 20.617  45.893  1.00 27.86  ? 302 THR F OG1 1 
ATOM   18079 C CG2 . THR F 1 302 ? -25.238 19.009  44.490  1.00 28.01  ? 302 THR F CG2 1 
ATOM   18080 N N   . LEU F 1 303 ? -28.366 19.514  47.776  1.00 25.35  ? 303 LEU F N   1 
ATOM   18081 C CA  . LEU F 1 303 ? -28.772 19.832  49.148  1.00 27.24  ? 303 LEU F CA  1 
ATOM   18082 C C   . LEU F 1 303 ? -29.764 18.823  49.704  1.00 26.98  ? 303 LEU F C   1 
ATOM   18083 O O   . LEU F 1 303 ? -29.735 18.509  50.901  1.00 25.12  ? 303 LEU F O   1 
ATOM   18084 C CB  . LEU F 1 303 ? -29.405 21.215  49.193  1.00 29.05  ? 303 LEU F CB  1 
ATOM   18085 C CG  . LEU F 1 303 ? -28.490 22.414  49.013  1.00 25.92  ? 303 LEU F CG  1 
ATOM   18086 C CD1 . LEU F 1 303 ? -29.360 23.594  48.616  1.00 24.01  ? 303 LEU F CD1 1 
ATOM   18087 C CD2 . LEU F 1 303 ? -27.702 22.703  50.274  1.00 22.12  ? 303 LEU F CD2 1 
ATOM   18088 N N   . LYS F 1 304 ? -30.690 18.355  48.865  1.00 26.72  ? 304 LYS F N   1 
ATOM   18089 C CA  . LYS F 1 304 ? -31.718 17.441  49.355  1.00 26.79  ? 304 LYS F CA  1 
ATOM   18090 C C   . LYS F 1 304 ? -31.126 16.105  49.779  1.00 24.89  ? 304 LYS F C   1 
ATOM   18091 O O   . LYS F 1 304 ? -31.365 15.686  50.924  1.00 27.91  ? 304 LYS F O   1 
ATOM   18092 C CB  . LYS F 1 304 ? -32.829 17.286  48.306  1.00 29.06  ? 304 LYS F CB  1 
ATOM   18093 C CG  . LYS F 1 304 ? -33.868 16.244  48.659  1.00 36.37  ? 304 LYS F CG  1 
ATOM   18094 C CD  . LYS F 1 304 ? -35.278 16.828  48.767  1.00 51.84  ? 304 LYS F CD  1 
ATOM   18095 C CE  . LYS F 1 304 ? -36.309 15.742  49.136  1.00 50.42  ? 304 LYS F CE  1 
ATOM   18096 N NZ  . LYS F 1 304 ? -36.865 15.036  47.936  1.00 56.59  ? 304 LYS F NZ  1 
ATOM   18097 N N   . PRO F 1 305 ? -30.358 15.396  48.956  1.00 25.98  ? 305 PRO F N   1 
ATOM   18098 C CA  . PRO F 1 305 ? -29.762 14.142  49.470  1.00 22.39  ? 305 PRO F CA  1 
ATOM   18099 C C   . PRO F 1 305 ? -28.834 14.365  50.657  1.00 27.57  ? 305 PRO F C   1 
ATOM   18100 O O   . PRO F 1 305 ? -28.902 13.618  51.648  1.00 21.87  ? 305 PRO F O   1 
ATOM   18101 C CB  . PRO F 1 305 ? -29.014 13.573  48.263  1.00 20.70  ? 305 PRO F CB  1 
ATOM   18102 C CG  . PRO F 1 305 ? -29.441 14.403  47.066  1.00 26.89  ? 305 PRO F CG  1 
ATOM   18103 C CD  . PRO F 1 305 ? -29.979 15.686  47.556  1.00 26.68  ? 305 PRO F CD  1 
ATOM   18104 N N   . ALA F 1 306 ? -27.973 15.389  50.592  1.00 26.32  ? 306 ALA F N   1 
ATOM   18105 C CA  . ALA F 1 306 ? -27.095 15.672  51.720  1.00 24.33  ? 306 ALA F CA  1 
ATOM   18106 C C   . ALA F 1 306 ? -27.891 15.869  53.006  1.00 26.37  ? 306 ALA F C   1 
ATOM   18107 O O   . ALA F 1 306 ? -27.521 15.325  54.053  1.00 25.35  ? 306 ALA F O   1 
ATOM   18108 C CB  . ALA F 1 306 ? -26.233 16.899  51.425  1.00 24.60  ? 306 ALA F CB  1 
ATOM   18109 N N   . GLU F 1 307 ? -29.003 16.626  52.946  1.00 25.49  ? 307 GLU F N   1 
ATOM   18110 C CA  . GLU F 1 307 ? -29.794 16.877  54.158  1.00 26.68  ? 307 GLU F CA  1 
ATOM   18111 C C   . GLU F 1 307 ? -30.392 15.582  54.700  1.00 21.96  ? 307 GLU F C   1 
ATOM   18112 O O   . GLU F 1 307 ? -30.445 15.366  55.922  1.00 18.80  ? 307 GLU F O   1 
ATOM   18113 C CB  . GLU F 1 307 ? -30.919 17.907  53.887  1.00 27.20  ? 307 GLU F CB  1 
ATOM   18114 C CG  . GLU F 1 307 ? -32.143 17.804  54.871  1.00 29.51  ? 307 GLU F CG  1 
ATOM   18115 C CD  . GLU F 1 307 ? -33.426 18.534  54.398  1.00 42.62  ? 307 GLU F CD  1 
ATOM   18116 O OE1 . GLU F 1 307 ? -33.343 19.568  53.703  1.00 45.01  ? 307 GLU F OE1 1 
ATOM   18117 O OE2 . GLU F 1 307 ? -34.538 18.037  54.692  1.00 52.02  ? 307 GLU F OE2 1 
ATOM   18118 N N   . GLU F 1 308 ? -30.859 14.717  53.805  1.00 19.14  ? 308 GLU F N   1 
ATOM   18119 C CA  . GLU F 1 308 ? -31.453 13.460  54.224  1.00 21.60  ? 308 GLU F CA  1 
ATOM   18120 C C   . GLU F 1 308 ? -30.404 12.540  54.848  1.00 25.12  ? 308 GLU F C   1 
ATOM   18121 O O   . GLU F 1 308 ? -30.661 11.916  55.883  1.00 25.83  ? 308 GLU F O   1 
ATOM   18122 C CB  . GLU F 1 308 ? -32.142 12.804  53.029  1.00 28.33  ? 308 GLU F CB  1 
ATOM   18123 C CG  . GLU F 1 308 ? -32.654 11.382  53.254  1.00 38.24  ? 308 GLU F CG  1 
ATOM   18124 C CD  . GLU F 1 308 ? -33.256 10.783  51.981  1.00 44.30  ? 308 GLU F CD  1 
ATOM   18125 O OE1 . GLU F 1 308 ? -34.023 11.489  51.297  1.00 50.32  ? 308 GLU F OE1 1 
ATOM   18126 O OE2 . GLU F 1 308 ? -32.944 9.620   51.648  1.00 42.24  ? 308 GLU F OE2 1 
ATOM   18127 N N   . PHE F 1 309 ? -29.199 12.477  54.269  1.00 23.13  ? 309 PHE F N   1 
ATOM   18128 C CA  . PHE F 1 309 ? -28.137 11.715  54.913  1.00 19.04  ? 309 PHE F CA  1 
ATOM   18129 C C   . PHE F 1 309 ? -27.804 12.293  56.278  1.00 20.63  ? 309 PHE F C   1 
ATOM   18130 O O   . PHE F 1 309 ? -27.666 11.559  57.257  1.00 20.07  ? 309 PHE F O   1 
ATOM   18131 C CB  . PHE F 1 309 ? -26.871 11.667  54.052  1.00 21.01  ? 309 PHE F CB  1 
ATOM   18132 C CG  . PHE F 1 309 ? -25.839 10.708  54.584  1.00 19.56  ? 309 PHE F CG  1 
ATOM   18133 C CD1 . PHE F 1 309 ? -24.969 11.089  55.594  1.00 17.96  ? 309 PHE F CD1 1 
ATOM   18134 C CD2 . PHE F 1 309 ? -25.773 9.413   54.105  1.00 19.85  ? 309 PHE F CD2 1 
ATOM   18135 C CE1 . PHE F 1 309 ? -24.054 10.199  56.117  1.00 18.76  ? 309 PHE F CE1 1 
ATOM   18136 C CE2 . PHE F 1 309 ? -24.824 8.504   54.611  1.00 23.33  ? 309 PHE F CE2 1 
ATOM   18137 C CZ  . PHE F 1 309 ? -23.977 8.903   55.626  1.00 23.81  ? 309 PHE F CZ  1 
ATOM   18138 N N   . ILE F 1 310 ? -27.606 13.611  56.347  1.00 26.37  ? 310 ILE F N   1 
ATOM   18139 C CA  . ILE F 1 310 ? -27.189 14.236  57.603  1.00 24.17  ? 310 ILE F CA  1 
ATOM   18140 C C   . ILE F 1 310 ? -28.255 14.023  58.660  1.00 22.01  ? 310 ILE F C   1 
ATOM   18141 O O   . ILE F 1 310 ? -27.952 13.748  59.831  1.00 23.62  ? 310 ILE F O   1 
ATOM   18142 C CB  . ILE F 1 310 ? -26.889 15.735  57.382  1.00 19.21  ? 310 ILE F CB  1 
ATOM   18143 C CG1 . ILE F 1 310 ? -25.552 15.904  56.676  1.00 19.32  ? 310 ILE F CG1 1 
ATOM   18144 C CG2 . ILE F 1 310 ? -26.856 16.473  58.702  1.00 23.64  ? 310 ILE F CG2 1 
ATOM   18145 C CD1 . ILE F 1 310 ? -24.392 15.475  57.520  1.00 20.45  ? 310 ILE F CD1 1 
ATOM   18146 N N   . GLU F 1 311 ? -29.523 14.138  58.258  1.00 22.27  ? 311 GLU F N   1 
ATOM   18147 C CA  . GLU F 1 311 ? -30.620 13.868  59.177  1.00 26.84  ? 311 GLU F CA  1 
ATOM   18148 C C   . GLU F 1 311 ? -30.549 12.447  59.700  1.00 23.21  ? 311 GLU F C   1 
ATOM   18149 O O   . GLU F 1 311 ? -30.824 12.189  60.874  1.00 25.68  ? 311 GLU F O   1 
ATOM   18150 C CB  . GLU F 1 311 ? -31.963 14.126  58.490  1.00 31.64  ? 311 GLU F CB  1 
ATOM   18151 C CG  . GLU F 1 311 ? -33.124 14.123  59.458  1.00 29.89  ? 311 GLU F CG  1 
ATOM   18152 C CD  . GLU F 1 311 ? -32.924 15.141  60.576  1.00 35.41  ? 311 GLU F CD  1 
ATOM   18153 O OE1 . GLU F 1 311 ? -32.291 16.188  60.320  1.00 37.15  ? 311 GLU F OE1 1 
ATOM   18154 O OE2 . GLU F 1 311 ? -33.377 14.883  61.707  1.00 37.41  ? 311 GLU F OE2 1 
ATOM   18155 N N   . MET F 1 312 ? -30.145 11.511  58.856  1.00 21.45  ? 312 MET F N   1 
ATOM   18156 C CA  . MET F 1 312 ? -29.972 10.158  59.347  1.00 21.84  ? 312 MET F CA  1 
ATOM   18157 C C   . MET F 1 312 ? -28.895 10.089  60.432  1.00 24.68  ? 312 MET F C   1 
ATOM   18158 O O   . MET F 1 312 ? -29.049 9.348   61.412  1.00 22.92  ? 312 MET F O   1 
ATOM   18159 C CB  . MET F 1 312 ? -29.644 9.224   58.190  1.00 20.73  ? 312 MET F CB  1 
ATOM   18160 C CG  . MET F 1 312 ? -29.833 7.764   58.532  1.00 24.31  ? 312 MET F CG  1 
ATOM   18161 S SD  . MET F 1 312 ? -28.227 7.008   58.541  1.00 52.07  ? 312 MET F SD  1 
ATOM   18162 C CE  . MET F 1 312 ? -28.093 6.667   56.799  1.00 25.79  ? 312 MET F CE  1 
ATOM   18163 N N   . ILE F 1 313 ? -27.801 10.850  60.291  1.00 20.90  ? 313 ILE F N   1 
ATOM   18164 C CA  . ILE F 1 313 ? -26.756 10.673  61.297  1.00 27.95  ? 313 ILE F CA  1 
ATOM   18165 C C   . ILE F 1 313 ? -27.153 11.384  62.607  1.00 21.19  ? 313 ILE F C   1 
ATOM   18166 O O   . ILE F 1 313 ? -26.742 10.961  63.681  1.00 19.89  ? 313 ILE F O   1 
ATOM   18167 C CB  . ILE F 1 313 ? -25.346 11.082  60.778  1.00 28.33  ? 313 ILE F CB  1 
ATOM   18168 C CG1 . ILE F 1 313 ? -25.072 12.565  60.745  1.00 27.65  ? 313 ILE F CG1 1 
ATOM   18169 C CG2 . ILE F 1 313 ? -24.976 10.455  59.429  1.00 31.42  ? 313 ILE F CG2 1 
ATOM   18170 C CD1 . ILE F 1 313 ? -24.429 13.021  62.046  1.00 30.20  ? 313 ILE F CD1 1 
ATOM   18171 N N   . ARG F 1 314 ? -28.014 12.400  62.557  1.00 22.16  ? 314 ARG F N   1 
ATOM   18172 C CA  . ARG F 1 314 ? -28.540 12.994  63.797  1.00 25.70  ? 314 ARG F CA  1 
ATOM   18173 C C   . ARG F 1 314 ? -29.479 12.032  64.531  1.00 24.26  ? 314 ARG F C   1 
ATOM   18174 O O   . ARG F 1 314 ? -29.502 11.988  65.773  1.00 23.52  ? 314 ARG F O   1 
ATOM   18175 C CB  . ARG F 1 314 ? -29.285 14.294  63.493  1.00 20.24  ? 314 ARG F CB  1 
ATOM   18176 C CG  . ARG F 1 314 ? -29.591 15.161  64.719  1.00 24.35  ? 314 ARG F CG  1 
ATOM   18177 C CD  . ARG F 1 314 ? -30.245 16.486  64.321  1.00 24.51  ? 314 ARG F CD  1 
ATOM   18178 N NE  . ARG F 1 314 ? -31.596 16.284  63.813  1.00 26.59  ? 314 ARG F NE  1 
ATOM   18179 C CZ  . ARG F 1 314 ? -32.659 16.067  64.576  1.00 28.68  ? 314 ARG F CZ  1 
ATOM   18180 N NH1 . ARG F 1 314 ? -32.577 16.082  65.891  1.00 29.78  ? 314 ARG F NH1 1 
ATOM   18181 N NH2 . ARG F 1 314 ? -33.838 15.842  64.004  1.00 27.52  ? 314 ARG F NH2 1 
ATOM   18182 N N   . THR F 1 315 ? -30.278 11.288  63.772  1.00 21.97  ? 315 THR F N   1 
ATOM   18183 C CA  . THR F 1 315 ? -31.104 10.224  64.327  1.00 24.89  ? 315 THR F CA  1 
ATOM   18184 C C   . THR F 1 315 ? -30.241 9.175   65.016  1.00 27.99  ? 315 THR F C   1 
ATOM   18185 O O   . THR F 1 315 ? -30.533 8.733   66.136  1.00 25.11  ? 315 THR F O   1 
ATOM   18186 C CB  . THR F 1 315 ? -31.916 9.600   63.193  1.00 20.77  ? 315 THR F CB  1 
ATOM   18187 O OG1 . THR F 1 315 ? -32.806 10.586  62.661  1.00 27.01  ? 315 THR F OG1 1 
ATOM   18188 C CG2 . THR F 1 315 ? -32.683 8.379   63.675  1.00 25.34  ? 315 THR F CG2 1 
ATOM   18189 N N   . ILE F 1 316 ? -29.175 8.756   64.344  1.00 27.22  ? 316 ILE F N   1 
ATOM   18190 C CA  . ILE F 1 316 ? -28.206 7.852   64.947  1.00 25.05  ? 316 ILE F CA  1 
ATOM   18191 C C   . ILE F 1 316 ? -27.708 8.409   66.275  1.00 28.17  ? 316 ILE F C   1 
ATOM   18192 O O   . ILE F 1 316 ? -27.561 7.679   67.259  1.00 28.93  ? 316 ILE F O   1 
ATOM   18193 C CB  . ILE F 1 316 ? -27.059 7.602   63.954  1.00 22.86  ? 316 ILE F CB  1 
ATOM   18194 C CG1 . ILE F 1 316 ? -27.557 6.701   62.812  1.00 27.75  ? 316 ILE F CG1 1 
ATOM   18195 C CG2 . ILE F 1 316 ? -25.861 6.966   64.670  1.00 30.08  ? 316 ILE F CG2 1 
ATOM   18196 C CD1 . ILE F 1 316 ? -26.505 6.442   61.734  1.00 27.87  ? 316 ILE F CD1 1 
ATOM   18197 N N   . GLY F 1 317 ? -27.456 9.713   66.334  1.00 27.98  ? 317 GLY F N   1 
ATOM   18198 C CA  . GLY F 1 317 ? -27.270 10.332  67.625  1.00 24.96  ? 317 GLY F CA  1 
ATOM   18199 C C   . GLY F 1 317 ? -26.050 11.216  67.692  1.00 27.05  ? 317 GLY F C   1 
ATOM   18200 O O   . GLY F 1 317 ? -25.641 11.634  68.775  1.00 26.43  ? 317 GLY F O   1 
ATOM   18201 N N   . TYR F 1 318 ? -25.438 11.503  66.553  1.00 22.75  ? 318 TYR F N   1 
ATOM   18202 C CA  . TYR F 1 318 ? -24.295 12.385  66.600  1.00 21.76  ? 318 TYR F CA  1 
ATOM   18203 C C   . TYR F 1 318 ? -24.752 13.797  66.921  1.00 21.58  ? 318 TYR F C   1 
ATOM   18204 O O   . TYR F 1 318 ? -25.789 14.260  66.439  1.00 23.58  ? 318 TYR F O   1 
ATOM   18205 C CB  . TYR F 1 318 ? -23.528 12.364  65.286  1.00 23.07  ? 318 TYR F CB  1 
ATOM   18206 C CG  . TYR F 1 318 ? -22.403 13.373  65.266  1.00 20.98  ? 318 TYR F CG  1 
ATOM   18207 C CD1 . TYR F 1 318 ? -21.244 13.148  65.985  1.00 22.70  ? 318 TYR F CD1 1 
ATOM   18208 C CD2 . TYR F 1 318 ? -22.516 14.564  64.548  1.00 24.07  ? 318 TYR F CD2 1 
ATOM   18209 C CE1 . TYR F 1 318 ? -20.200 14.069  65.983  1.00 22.39  ? 318 TYR F CE1 1 
ATOM   18210 C CE2 . TYR F 1 318 ? -21.482 15.507  64.540  1.00 23.72  ? 318 TYR F CE2 1 
ATOM   18211 C CZ  . TYR F 1 318 ? -20.327 15.251  65.261  1.00 27.20  ? 318 TYR F CZ  1 
ATOM   18212 O OH  . TYR F 1 318 ? -19.291 16.165  65.244  1.00 26.04  ? 318 TYR F OH  1 
ATOM   18213 N N   . ARG F 1 319 ? -23.979 14.466  67.760  1.00 20.62  ? 319 ARG F N   1 
ATOM   18214 C CA  . ARG F 1 319 ? -24.223 15.844  68.171  1.00 24.36  ? 319 ARG F CA  1 
ATOM   18215 C C   . ARG F 1 319 ? -22.940 16.629  67.952  1.00 21.62  ? 319 ARG F C   1 
ATOM   18216 O O   . ARG F 1 319 ? -21.855 16.143  68.280  1.00 19.70  ? 319 ARG F O   1 
ATOM   18217 C CB  . ARG F 1 319 ? -24.650 15.917  69.646  1.00 26.30  ? 319 ARG F CB  1 
ATOM   18218 C CG  . ARG F 1 319 ? -25.919 15.111  69.982  1.00 23.94  ? 319 ARG F CG  1 
ATOM   18219 C CD  . ARG F 1 319 ? -27.141 15.706  69.287  1.00 24.51  ? 319 ARG F CD  1 
ATOM   18220 N NE  . ARG F 1 319 ? -28.359 14.979  69.640  1.00 27.99  ? 319 ARG F NE  1 
ATOM   18221 C CZ  . ARG F 1 319 ? -28.932 14.065  68.874  1.00 26.59  ? 319 ARG F CZ  1 
ATOM   18222 N NH1 . ARG F 1 319 ? -28.427 13.734  67.694  1.00 21.22  ? 319 ARG F NH1 1 
ATOM   18223 N NH2 . ARG F 1 319 ? -30.037 13.459  69.306  1.00 28.37  ? 319 ARG F NH2 1 
ATOM   18224 N N   . GLY F 1 320 ? -23.062 17.821  67.380  1.00 22.78  ? 320 GLY F N   1 
ATOM   18225 C CA  . GLY F 1 320 ? -21.895 18.613  67.023  1.00 24.64  ? 320 GLY F CA  1 
ATOM   18226 C C   . GLY F 1 320 ? -21.805 18.935  65.540  1.00 23.17  ? 320 GLY F C   1 
ATOM   18227 O O   . GLY F 1 320 ? -22.807 18.893  64.817  1.00 20.01  ? 320 GLY F O   1 
ATOM   18228 N N   . TYR F 1 321 ? -20.597 19.229  65.068  1.00 23.47  ? 321 TYR F N   1 
ATOM   18229 C CA  . TYR F 1 321 ? -20.392 19.680  63.701  1.00 22.22  ? 321 TYR F CA  1 
ATOM   18230 C C   . TYR F 1 321 ? -20.080 18.507  62.777  1.00 21.48  ? 321 TYR F C   1 
ATOM   18231 O O   . TYR F 1 321 ? -19.407 17.556  63.171  1.00 22.98  ? 321 TYR F O   1 
ATOM   18232 C CB  . TYR F 1 321 ? -19.256 20.702  63.668  1.00 26.22  ? 321 TYR F CB  1 
ATOM   18233 C CG  . TYR F 1 321 ? -19.596 21.983  64.396  1.00 23.99  ? 321 TYR F CG  1 
ATOM   18234 C CD1 . TYR F 1 321 ? -20.344 22.967  63.760  1.00 24.41  ? 321 TYR F CD1 1 
ATOM   18235 C CD2 . TYR F 1 321 ? -19.195 22.204  65.716  1.00 23.82  ? 321 TYR F CD2 1 
ATOM   18236 C CE1 . TYR F 1 321 ? -20.672 24.141  64.400  1.00 25.12  ? 321 TYR F CE1 1 
ATOM   18237 C CE2 . TYR F 1 321 ? -19.524 23.394  66.371  1.00 20.37  ? 321 TYR F CE2 1 
ATOM   18238 C CZ  . TYR F 1 321 ? -20.259 24.351  65.699  1.00 24.44  ? 321 TYR F CZ  1 
ATOM   18239 O OH  . TYR F 1 321 ? -20.601 25.554  66.290  1.00 22.91  ? 321 TYR F OH  1 
ATOM   18240 N N   . VAL F 1 322 ? -20.555 18.581  61.535  1.00 22.49  ? 322 VAL F N   1 
ATOM   18241 C CA  . VAL F 1 322 ? -20.331 17.497  60.586  1.00 21.51  ? 322 VAL F CA  1 
ATOM   18242 C C   . VAL F 1 322 ? -20.402 18.042  59.165  1.00 20.62  ? 322 VAL F C   1 
ATOM   18243 O O   . VAL F 1 322 ? -21.168 18.967  58.869  1.00 23.29  ? 322 VAL F O   1 
ATOM   18244 C CB  . VAL F 1 322 ? -21.339 16.344  60.828  1.00 19.08  ? 322 VAL F CB  1 
ATOM   18245 C CG1 . VAL F 1 322 ? -22.777 16.797  60.541  1.00 16.90  ? 322 VAL F CG1 1 
ATOM   18246 C CG2 . VAL F 1 322 ? -20.950 15.128  60.020  1.00 18.03  ? 322 VAL F CG2 1 
ATOM   18247 N N   . ASN F 1 323 ? -19.579 17.482  58.274  1.00 21.25  ? 323 ASN F N   1 
ATOM   18248 C CA  . ASN F 1 323 ? -19.606 17.905  56.877  1.00 20.03  ? 323 ASN F CA  1 
ATOM   18249 C C   . ASN F 1 323 ? -19.645 16.704  55.944  1.00 21.31  ? 323 ASN F C   1 
ATOM   18250 O O   . ASN F 1 323 ? -19.199 15.612  56.288  1.00 21.42  ? 323 ASN F O   1 
ATOM   18251 C CB  . ASN F 1 323 ? -18.406 18.820  56.496  1.00 21.71  ? 323 ASN F CB  1 
ATOM   18252 C CG  . ASN F 1 323 ? -17.057 18.194  56.798  1.00 24.80  ? 323 ASN F CG  1 
ATOM   18253 O OD1 . ASN F 1 323 ? -16.597 18.187  57.945  1.00 26.47  ? 323 ASN F OD1 1 
ATOM   18254 N ND2 . ASN F 1 323 ? -16.411 17.679  55.767  1.00 25.32  ? 323 ASN F ND2 1 
ATOM   18255 N N   . ILE F 1 324 ? -20.230 16.922  54.771  1.00 18.27  ? 324 ILE F N   1 
ATOM   18256 C CA  . ILE F 1 324 ? -20.295 15.947  53.699  1.00 18.82  ? 324 ILE F CA  1 
ATOM   18257 C C   . ILE F 1 324 ? -19.734 16.619  52.459  1.00 22.03  ? 324 ILE F C   1 
ATOM   18258 O O   . ILE F 1 324 ? -20.056 17.778  52.178  1.00 22.03  ? 324 ILE F O   1 
ATOM   18259 C CB  . ILE F 1 324 ? -21.737 15.456  53.464  1.00 20.89  ? 324 ILE F CB  1 
ATOM   18260 C CG1 . ILE F 1 324 ? -21.801 14.357  52.418  1.00 18.22  ? 324 ILE F CG1 1 
ATOM   18261 C CG2 . ILE F 1 324 ? -22.703 16.614  53.109  1.00 21.65  ? 324 ILE F CG2 1 
ATOM   18262 C CD1 . ILE F 1 324 ? -23.088 13.517  52.537  1.00 23.10  ? 324 ILE F CD1 1 
ATOM   18263 N N   . ASP F 1 325 ? -18.869 15.921  51.742  1.00 17.65  ? 325 ASP F N   1 
ATOM   18264 C CA  . ASP F 1 325 ? -18.294 16.482  50.538  1.00 20.32  ? 325 ASP F CA  1 
ATOM   18265 C C   . ASP F 1 325 ? -18.778 15.679  49.341  1.00 22.95  ? 325 ASP F C   1 
ATOM   18266 O O   . ASP F 1 325 ? -19.109 14.497  49.461  1.00 20.43  ? 325 ASP F O   1 
ATOM   18267 C CB  . ASP F 1 325 ? -16.777 16.478  50.596  1.00 22.80  ? 325 ASP F CB  1 
ATOM   18268 C CG  . ASP F 1 325 ? -16.202 15.160  50.173  1.00 30.09  ? 325 ASP F CG  1 
ATOM   18269 O OD1 . ASP F 1 325 ? -16.400 14.182  50.917  1.00 31.39  ? 325 ASP F OD1 1 
ATOM   18270 O OD2 . ASP F 1 325 ? -15.610 15.088  49.071  1.00 35.27  ? 325 ASP F OD2 1 
ATOM   18271 N N   . GLY F 1 326 ? -18.858 16.346  48.197  1.00 18.45  ? 326 GLY F N   1 
ATOM   18272 C CA  . GLY F 1 326 ? -19.316 15.689  46.995  1.00 23.41  ? 326 GLY F CA  1 
ATOM   18273 C C   . GLY F 1 326 ? -18.821 16.406  45.761  1.00 26.36  ? 326 GLY F C   1 
ATOM   18274 O O   . GLY F 1 326 ? -18.094 17.396  45.838  1.00 23.32  ? 326 GLY F O   1 
ATOM   18275 N N   . ILE F 1 327 ? -19.236 15.899  44.604  1.00 21.77  ? 327 ILE F N   1 
ATOM   18276 C CA  . ILE F 1 327 ? -18.848 16.490  43.336  1.00 25.60  ? 327 ILE F CA  1 
ATOM   18277 C C   . ILE F 1 327 ? -20.066 16.524  42.426  1.00 24.68  ? 327 ILE F C   1 
ATOM   18278 O O   . ILE F 1 327 ? -21.004 15.744  42.584  1.00 24.51  ? 327 ILE F O   1 
ATOM   18279 C CB  . ILE F 1 327 ? -17.693 15.704  42.676  1.00 23.35  ? 327 ILE F CB  1 
ATOM   18280 C CG1 . ILE F 1 327 ? -18.139 14.264  42.370  1.00 25.70  ? 327 ILE F CG1 1 
ATOM   18281 C CG2 . ILE F 1 327 ? -16.469 15.696  43.561  1.00 23.89  ? 327 ILE F CG2 1 
ATOM   18282 C CD1 . ILE F 1 327 ? -16.999 13.381  41.897  1.00 27.31  ? 327 ILE F CD1 1 
ATOM   18283 N N   . VAL F 1 328 ? -20.057 17.458  41.484  1.00 25.38  ? 328 VAL F N   1 
ATOM   18284 C CA  . VAL F 1 328 ? -20.981 17.473  40.359  1.00 29.47  ? 328 VAL F CA  1 
ATOM   18285 C C   . VAL F 1 328 ? -20.163 17.241  39.099  1.00 30.11  ? 328 VAL F C   1 
ATOM   18286 O O   . VAL F 1 328 ? -19.131 17.887  38.910  1.00 34.67  ? 328 VAL F O   1 
ATOM   18287 C CB  . VAL F 1 328 ? -21.740 18.810  40.276  1.00 36.34  ? 328 VAL F CB  1 
ATOM   18288 C CG1 . VAL F 1 328 ? -22.824 18.732  39.200  1.00 34.40  ? 328 VAL F CG1 1 
ATOM   18289 C CG2 . VAL F 1 328 ? -22.316 19.193  41.656  1.00 29.02  ? 328 VAL F CG2 1 
ATOM   18290 N N   . LEU F 1 329 ? -20.610 16.316  38.250  1.00 33.91  ? 329 LEU F N   1 
ATOM   18291 C CA  . LEU F 1 329 ? -19.943 16.032  36.986  1.00 39.60  ? 329 LEU F CA  1 
ATOM   18292 C C   . LEU F 1 329 ? -20.432 16.994  35.898  1.00 40.78  ? 329 LEU F C   1 
ATOM   18293 O O   . LEU F 1 329 ? -21.443 17.685  36.057  1.00 40.62  ? 329 LEU F O   1 
ATOM   18294 C CB  . LEU F 1 329 ? -20.188 14.579  36.553  1.00 35.93  ? 329 LEU F CB  1 
ATOM   18295 C CG  . LEU F 1 329 ? -19.855 13.365  37.432  1.00 37.97  ? 329 LEU F CG  1 
ATOM   18296 C CD1 . LEU F 1 329 ? -19.572 12.123  36.553  1.00 31.35  ? 329 LEU F CD1 1 
ATOM   18297 C CD2 . LEU F 1 329 ? -18.700 13.623  38.394  1.00 27.63  ? 329 LEU F CD2 1 
ATOM   18298 N N   . ASP F 1 330 ? -19.706 17.024  34.769  1.00 42.00  ? 330 ASP F N   1 
ATOM   18299 C CA  . ASP F 1 330 ? -20.090 17.913  33.668  1.00 46.01  ? 330 ASP F CA  1 
ATOM   18300 C C   . ASP F 1 330 ? -21.520 17.653  33.211  1.00 42.46  ? 330 ASP F C   1 
ATOM   18301 O O   . ASP F 1 330 ? -22.246 18.591  32.864  1.00 45.02  ? 330 ASP F O   1 
ATOM   18302 C CB  . ASP F 1 330 ? -19.128 17.774  32.482  1.00 42.70  ? 330 ASP F CB  1 
ATOM   18303 C CG  . ASP F 1 330 ? -18.696 16.328  32.215  1.00 54.01  ? 330 ASP F CG  1 
ATOM   18304 O OD1 . ASP F 1 330 ? -19.442 15.379  32.568  1.00 48.85  ? 330 ASP F OD1 1 
ATOM   18305 O OD2 . ASP F 1 330 ? -17.600 16.149  31.620  1.00 56.53  ? 330 ASP F OD2 1 
ATOM   18306 N N   . ASP F 1 331 ? -21.944 16.391  33.220  1.00 38.06  ? 331 ASP F N   1 
ATOM   18307 C CA  . ASP F 1 331 ? -23.286 15.987  32.829  1.00 41.29  ? 331 ASP F CA  1 
ATOM   18308 C C   . ASP F 1 331 ? -24.310 16.140  33.942  1.00 39.96  ? 331 ASP F C   1 
ATOM   18309 O O   . ASP F 1 331 ? -25.432 15.656  33.780  1.00 39.00  ? 331 ASP F O   1 
ATOM   18310 C CB  . ASP F 1 331 ? -23.275 14.532  32.350  1.00 43.79  ? 331 ASP F CB  1 
ATOM   18311 C CG  . ASP F 1 331 ? -22.581 13.601  33.336  1.00 48.26  ? 331 ASP F CG  1 
ATOM   18312 O OD1 . ASP F 1 331 ? -23.257 13.023  34.218  1.00 41.57  ? 331 ASP F OD1 1 
ATOM   18313 O OD2 . ASP F 1 331 ? -21.340 13.478  33.242  1.00 51.29  ? 331 ASP F OD2 1 
ATOM   18314 N N   . GLY F 1 332 ? -23.950 16.758  35.067  1.00 39.71  ? 332 GLY F N   1 
ATOM   18315 C CA  . GLY F 1 332 ? -24.909 17.017  36.123  1.00 37.43  ? 332 GLY F CA  1 
ATOM   18316 C C   . GLY F 1 332 ? -25.164 15.881  37.085  1.00 36.84  ? 332 GLY F C   1 
ATOM   18317 O O   . GLY F 1 332 ? -26.098 15.969  37.890  1.00 38.28  ? 332 GLY F O   1 
ATOM   18318 N N   . ARG F 1 333 ? -24.380 14.812  37.028  1.00 38.90  ? 333 ARG F N   1 
ATOM   18319 C CA  . ARG F 1 333 ? -24.487 13.746  38.014  1.00 35.95  ? 333 ARG F CA  1 
ATOM   18320 C C   . ARG F 1 333 ? -23.793 14.149  39.303  1.00 35.44  ? 333 ARG F C   1 
ATOM   18321 O O   . ARG F 1 333 ? -22.670 14.664  39.284  1.00 36.45  ? 333 ARG F O   1 
ATOM   18322 C CB  . ARG F 1 333 ? -23.865 12.460  37.488  1.00 35.08  ? 333 ARG F CB  1 
ATOM   18323 C CG  . ARG F 1 333 ? -24.777 11.702  36.564  1.00 37.65  ? 333 ARG F CG  1 
ATOM   18324 C CD  . ARG F 1 333 ? -24.182 10.364  36.253  1.00 34.91  ? 333 ARG F CD  1 
ATOM   18325 N NE  . ARG F 1 333 ? -22.940 10.478  35.504  1.00 31.96  ? 333 ARG F NE  1 
ATOM   18326 C CZ  . ARG F 1 333 ? -22.103 9.468   35.324  1.00 39.14  ? 333 ARG F CZ  1 
ATOM   18327 N NH1 . ARG F 1 333 ? -22.333 8.283   35.863  1.00 33.86  ? 333 ARG F NH1 1 
ATOM   18328 N NH2 . ARG F 1 333 ? -21.011 9.649   34.581  1.00 40.79  ? 333 ARG F NH2 1 
ATOM   18329 N N   . VAL F 1 334 ? -24.464 13.896  40.428  1.00 30.86  ? 334 VAL F N   1 
ATOM   18330 C CA  . VAL F 1 334 ? -23.977 14.260  41.749  1.00 25.21  ? 334 VAL F CA  1 
ATOM   18331 C C   . VAL F 1 334 ? -23.500 13.005  42.467  1.00 30.92  ? 334 VAL F C   1 
ATOM   18332 O O   . VAL F 1 334 ? -24.142 11.953  42.380  1.00 27.31  ? 334 VAL F O   1 
ATOM   18333 C CB  . VAL F 1 334 ? -25.097 14.971  42.531  1.00 28.79  ? 334 VAL F CB  1 
ATOM   18334 C CG1 . VAL F 1 334 ? -24.686 15.275  43.967  1.00 24.66  ? 334 VAL F CG1 1 
ATOM   18335 C CG2 . VAL F 1 334 ? -25.520 16.237  41.789  1.00 30.70  ? 334 VAL F CG2 1 
ATOM   18336 N N   . PHE F 1 335 ? -22.375 13.113  43.180  1.00 24.90  ? 335 PHE F N   1 
ATOM   18337 C CA  . PHE F 1 335 ? -21.904 12.038  44.045  1.00 25.96  ? 335 PHE F CA  1 
ATOM   18338 C C   . PHE F 1 335 ? -21.442 12.623  45.372  1.00 25.39  ? 335 PHE F C   1 
ATOM   18339 O O   . PHE F 1 335 ? -20.839 13.697  45.398  1.00 25.37  ? 335 PHE F O   1 
ATOM   18340 C CB  . PHE F 1 335 ? -20.741 11.262  43.422  1.00 30.04  ? 335 PHE F CB  1 
ATOM   18341 C CG  . PHE F 1 335 ? -21.119 10.421  42.236  1.00 28.93  ? 335 PHE F CG  1 
ATOM   18342 C CD1 . PHE F 1 335 ? -21.991 9.352   42.372  1.00 31.25  ? 335 PHE F CD1 1 
ATOM   18343 C CD2 . PHE F 1 335 ? -20.576 10.686  40.988  1.00 30.33  ? 335 PHE F CD2 1 
ATOM   18344 C CE1 . PHE F 1 335 ? -22.329 8.574   41.272  1.00 34.13  ? 335 PHE F CE1 1 
ATOM   18345 C CE2 . PHE F 1 335 ? -20.895 9.905   39.885  1.00 29.63  ? 335 PHE F CE2 1 
ATOM   18346 C CZ  . PHE F 1 335 ? -21.777 8.858   40.022  1.00 29.92  ? 335 PHE F CZ  1 
ATOM   18347 N N   . PHE F 1 336 ? -21.723 11.921  46.471  1.00 22.25  ? 336 PHE F N   1 
ATOM   18348 C CA  . PHE F 1 336 ? -21.199 12.281  47.780  1.00 22.93  ? 336 PHE F CA  1 
ATOM   18349 C C   . PHE F 1 336 ? -20.116 11.284  48.161  1.00 24.19  ? 336 PHE F C   1 
ATOM   18350 O O   . PHE F 1 336 ? -20.255 10.087  47.913  1.00 23.07  ? 336 PHE F O   1 
ATOM   18351 C CB  . PHE F 1 336 ? -22.318 12.326  48.832  1.00 24.27  ? 336 PHE F CB  1 
ATOM   18352 C CG  . PHE F 1 336 ? -23.308 13.416  48.577  1.00 23.54  ? 336 PHE F CG  1 
ATOM   18353 C CD1 . PHE F 1 336 ? -23.049 14.718  48.992  1.00 22.72  ? 336 PHE F CD1 1 
ATOM   18354 C CD2 . PHE F 1 336 ? -24.458 13.164  47.845  1.00 20.88  ? 336 PHE F CD2 1 
ATOM   18355 C CE1 . PHE F 1 336 ? -23.940 15.746  48.713  1.00 21.98  ? 336 PHE F CE1 1 
ATOM   18356 C CE2 . PHE F 1 336 ? -25.363 14.186  47.569  1.00 22.35  ? 336 PHE F CE2 1 
ATOM   18357 C CZ  . PHE F 1 336 ? -25.106 15.472  48.010  1.00 25.01  ? 336 PHE F CZ  1 
ATOM   18358 N N   . HIS F 1 337 ? -19.042 11.782  48.772  1.00 25.42  ? 337 HIS F N   1 
ATOM   18359 C CA  . HIS F 1 337 ? -17.810 11.025  48.947  1.00 25.31  ? 337 HIS F CA  1 
ATOM   18360 C C   . HIS F 1 337 ? -17.546 10.578  50.377  1.00 28.19  ? 337 HIS F C   1 
ATOM   18361 O O   . HIS F 1 337 ? -17.163 9.426   50.591  1.00 27.35  ? 337 HIS F O   1 
ATOM   18362 C CB  . HIS F 1 337 ? -16.624 11.863  48.451  1.00 28.89  ? 337 HIS F CB  1 
ATOM   18363 C CG  . HIS F 1 337 ? -16.397 11.760  46.982  1.00 27.31  ? 337 HIS F CG  1 
ATOM   18364 N ND1 . HIS F 1 337 ? -16.763 10.649  46.249  1.00 34.69  ? 337 HIS F ND1 1 
ATOM   18365 C CD2 . HIS F 1 337 ? -15.867 12.637  46.098  1.00 39.49  ? 337 HIS F CD2 1 
ATOM   18366 C CE1 . HIS F 1 337 ? -16.447 10.835  44.980  1.00 34.40  ? 337 HIS F CE1 1 
ATOM   18367 N NE2 . HIS F 1 337 ? -15.907 12.036  44.860  1.00 43.43  ? 337 HIS F NE2 1 
ATOM   18368 N N   . GLU F 1 338 ? -17.688 11.459  51.367  1.00 25.58  ? 338 GLU F N   1 
ATOM   18369 C CA  . GLU F 1 338 ? -17.440 11.068  52.752  1.00 24.14  ? 338 GLU F CA  1 
ATOM   18370 C C   . GLU F 1 338 ? -18.087 12.080  53.680  1.00 22.24  ? 338 GLU F C   1 
ATOM   18371 O O   . GLU F 1 338 ? -18.516 13.167  53.272  1.00 21.07  ? 338 GLU F O   1 
ATOM   18372 C CB  . GLU F 1 338 ? -15.936 10.964  53.064  1.00 30.13  ? 338 GLU F CB  1 
ATOM   18373 C CG  . GLU F 1 338 ? -15.160 12.137  52.520  1.00 28.65  ? 338 GLU F CG  1 
ATOM   18374 C CD  . GLU F 1 338 ? -13.713 12.236  52.982  1.00 36.04  ? 338 GLU F CD  1 
ATOM   18375 O OE1 . GLU F 1 338 ? -12.959 11.254  52.809  1.00 33.41  ? 338 GLU F OE1 1 
ATOM   18376 O OE2 . GLU F 1 338 ? -13.321 13.334  53.462  1.00 40.07  ? 338 GLU F OE2 1 
ATOM   18377 N N   . ILE F 1 339 ? -18.159 11.702  54.940  1.00 23.92  ? 339 ILE F N   1 
ATOM   18378 C CA  . ILE F 1 339 ? -18.553 12.633  55.977  1.00 21.83  ? 339 ILE F CA  1 
ATOM   18379 C C   . ILE F 1 339 ? -17.421 12.708  56.985  1.00 27.24  ? 339 ILE F C   1 
ATOM   18380 O O   . ILE F 1 339 ? -16.599 11.794  57.118  1.00 23.94  ? 339 ILE F O   1 
ATOM   18381 C CB  . ILE F 1 339 ? -19.875 12.263  56.672  1.00 22.40  ? 339 ILE F CB  1 
ATOM   18382 C CG1 . ILE F 1 339 ? -19.803 10.868  57.282  1.00 22.64  ? 339 ILE F CG1 1 
ATOM   18383 C CG2 . ILE F 1 339 ? -21.054 12.435  55.724  1.00 24.33  ? 339 ILE F CG2 1 
ATOM   18384 C CD1 . ILE F 1 339 ? -20.659 10.765  58.512  1.00 21.33  ? 339 ILE F CD1 1 
ATOM   18385 N N   . ASN F 1 340 ? -17.380 13.827  57.690  1.00 22.60  ? 340 ASN F N   1 
ATOM   18386 C CA  . ASN F 1 340 ? -16.416 14.015  58.761  1.00 25.52  ? 340 ASN F CA  1 
ATOM   18387 C C   . ASN F 1 340 ? -17.179 14.614  59.919  1.00 26.66  ? 340 ASN F C   1 
ATOM   18388 O O   . ASN F 1 340 ? -17.642 15.760  59.822  1.00 26.56  ? 340 ASN F O   1 
ATOM   18389 C CB  . ASN F 1 340 ? -15.278 14.929  58.349  1.00 28.67  ? 340 ASN F CB  1 
ATOM   18390 C CG  . ASN F 1 340 ? -14.405 14.319  57.295  1.00 32.42  ? 340 ASN F CG  1 
ATOM   18391 O OD1 . ASN F 1 340 ? -13.917 13.198  57.440  1.00 34.22  ? 340 ASN F OD1 1 
ATOM   18392 N ND2 . ASN F 1 340 ? -14.201 15.060  56.210  1.00 33.67  ? 340 ASN F ND2 1 
ATOM   18393 N N   . ALA F 1 341 ? -17.311 13.830  60.991  1.00 21.96  ? 341 ALA F N   1 
ATOM   18394 C CA  . ALA F 1 341 ? -17.956 14.274  62.217  1.00 27.33  ? 341 ALA F CA  1 
ATOM   18395 C C   . ALA F 1 341 ? -16.879 14.902  63.099  1.00 27.58  ? 341 ALA F C   1 
ATOM   18396 O O   . ALA F 1 341 ? -16.295 14.266  63.981  1.00 23.86  ? 341 ALA F O   1 
ATOM   18397 C CB  . ALA F 1 341 ? -18.664 13.112  62.897  1.00 18.99  ? 341 ALA F CB  1 
ATOM   18398 N N   . ARG F 1 342 ? -16.608 16.178  62.825  1.00 26.06  ? 342 ARG F N   1 
ATOM   18399 C CA  . ARG F 1 342 ? -15.625 17.018  63.504  1.00 23.59  ? 342 ARG F CA  1 
ATOM   18400 C C   . ARG F 1 342 ? -15.647 18.347  62.764  1.00 23.12  ? 342 ARG F C   1 
ATOM   18401 O O   . ARG F 1 342 ? -16.279 18.471  61.703  1.00 17.82  ? 342 ARG F O   1 
ATOM   18402 C CB  . ARG F 1 342 ? -14.214 16.401  63.509  1.00 26.40  ? 342 ARG F CB  1 
ATOM   18403 C CG  . ARG F 1 342 ? -13.627 16.236  62.108  1.00 27.66  ? 342 ARG F CG  1 
ATOM   18404 C CD  . ARG F 1 342 ? -12.409 15.296  62.107  1.00 35.34  ? 342 ARG F CD  1 
ATOM   18405 N NE  . ARG F 1 342 ? -11.537 15.493  60.952  1.00 35.85  ? 342 ARG F NE  1 
ATOM   18406 C CZ  . ARG F 1 342 ? -11.607 14.796  59.828  1.00 37.04  ? 342 ARG F CZ  1 
ATOM   18407 N NH1 . ARG F 1 342 ? -12.520 13.858  59.654  1.00 42.51  ? 342 ARG F NH1 1 
ATOM   18408 N NH2 . ARG F 1 342 ? -10.741 15.047  58.852  1.00 44.66  ? 342 ARG F NH2 1 
ATOM   18409 N N   . TRP F 1 343 ? -14.962 19.345  63.334  1.00 23.38  ? 343 TRP F N   1 
ATOM   18410 C CA  . TRP F 1 343 ? -14.817 20.625  62.643  1.00 20.41  ? 343 TRP F CA  1 
ATOM   18411 C C   . TRP F 1 343 ? -14.232 20.399  61.260  1.00 25.16  ? 343 TRP F C   1 
ATOM   18412 O O   . TRP F 1 343 ? -13.197 19.743  61.107  1.00 24.89  ? 343 TRP F O   1 
ATOM   18413 C CB  . TRP F 1 343 ? -13.887 21.578  63.393  1.00 22.21  ? 343 TRP F CB  1 
ATOM   18414 C CG  . TRP F 1 343 ? -14.258 21.922  64.770  1.00 26.32  ? 343 TRP F CG  1 
ATOM   18415 C CD1 . TRP F 1 343 ? -15.496 21.816  65.353  1.00 25.82  ? 343 TRP F CD1 1 
ATOM   18416 C CD2 . TRP F 1 343 ? -13.380 22.431  65.768  1.00 25.19  ? 343 TRP F CD2 1 
ATOM   18417 N NE1 . TRP F 1 343 ? -15.430 22.226  66.665  1.00 26.95  ? 343 TRP F NE1 1 
ATOM   18418 C CE2 . TRP F 1 343 ? -14.144 22.616  66.943  1.00 26.02  ? 343 TRP F CE2 1 
ATOM   18419 C CE3 . TRP F 1 343 ? -12.018 22.761  65.783  1.00 24.08  ? 343 TRP F CE3 1 
ATOM   18420 C CZ2 . TRP F 1 343 ? -13.587 23.105  68.124  1.00 24.41  ? 343 TRP F CZ2 1 
ATOM   18421 C CZ3 . TRP F 1 343 ? -11.467 23.252  66.948  1.00 24.24  ? 343 TRP F CZ3 1 
ATOM   18422 C CH2 . TRP F 1 343 ? -12.247 23.418  68.104  1.00 28.81  ? 343 TRP F CH2 1 
ATOM   18423 N N   . SER F 1 344 ? -14.879 20.953  60.254  1.00 22.19  ? 344 SER F N   1 
ATOM   18424 C CA  . SER F 1 344 ? -14.189 21.031  58.986  1.00 25.07  ? 344 SER F CA  1 
ATOM   18425 C C   . SER F 1 344 ? -13.041 22.032  59.091  1.00 24.21  ? 344 SER F C   1 
ATOM   18426 O O   . SER F 1 344 ? -12.991 22.877  59.992  1.00 23.90  ? 344 SER F O   1 
ATOM   18427 C CB  . SER F 1 344 ? -15.156 21.452  57.882  1.00 26.38  ? 344 SER F CB  1 
ATOM   18428 O OG  . SER F 1 344 ? -15.410 22.850  57.941  1.00 26.70  ? 344 SER F OG  1 
ATOM   18429 N N   . GLY F 1 345 ? -12.126 21.965  58.129  1.00 30.56  ? 345 GLY F N   1 
ATOM   18430 C CA  . GLY F 1 345 ? -11.117 23.008  58.031  1.00 23.39  ? 345 GLY F CA  1 
ATOM   18431 C C   . GLY F 1 345 ? -11.690 24.372  57.684  1.00 24.66  ? 345 GLY F C   1 
ATOM   18432 O O   . GLY F 1 345 ? -11.045 25.390  57.931  1.00 27.35  ? 345 GLY F O   1 
ATOM   18433 N N   . GLY F 1 346 ? -12.897 24.419  57.103  1.00 20.94  ? 346 GLY F N   1 
ATOM   18434 C CA  . GLY F 1 346 ? -13.540 25.672  56.739  1.00 22.43  ? 346 GLY F CA  1 
ATOM   18435 C C   . GLY F 1 346 ? -14.508 26.244  57.761  1.00 26.08  ? 346 GLY F C   1 
ATOM   18436 O O   . GLY F 1 346 ? -15.088 27.315  57.527  1.00 21.87  ? 346 GLY F O   1 
ATOM   18437 N N   . LEU F 1 347 ? -14.700 25.554  58.894  1.00 25.94  ? 347 LEU F N   1 
ATOM   18438 C CA  . LEU F 1 347 ? -15.597 26.050  59.937  1.00 26.31  ? 347 LEU F CA  1 
ATOM   18439 C C   . LEU F 1 347 ? -15.131 27.399  60.452  1.00 25.22  ? 347 LEU F C   1 
ATOM   18440 O O   . LEU F 1 347 ? -15.936 28.321  60.623  1.00 24.75  ? 347 LEU F O   1 
ATOM   18441 C CB  . LEU F 1 347 ? -15.689 25.065  61.107  1.00 22.45  ? 347 LEU F CB  1 
ATOM   18442 C CG  . LEU F 1 347 ? -16.552 25.500  62.300  1.00 21.53  ? 347 LEU F CG  1 
ATOM   18443 C CD1 . LEU F 1 347 ? -17.982 25.852  61.868  1.00 22.66  ? 347 LEU F CD1 1 
ATOM   18444 C CD2 . LEU F 1 347 ? -16.588 24.445  63.425  1.00 19.86  ? 347 LEU F CD2 1 
ATOM   18445 N N   . ILE F 1 348 ? -13.834 27.524  60.719  1.00 22.13  ? 348 ILE F N   1 
ATOM   18446 C CA  . ILE F 1 348 ? -13.321 28.770  61.274  1.00 22.75  ? 348 ILE F CA  1 
ATOM   18447 C C   . ILE F 1 348 ? -13.522 29.914  60.295  1.00 21.19  ? 348 ILE F C   1 
ATOM   18448 O O   . ILE F 1 348 ? -13.808 31.045  60.707  1.00 23.65  ? 348 ILE F O   1 
ATOM   18449 C CB  . ILE F 1 348 ? -11.847 28.598  61.691  1.00 27.06  ? 348 ILE F CB  1 
ATOM   18450 C CG1 . ILE F 1 348 ? -11.397 29.808  62.501  1.00 25.08  ? 348 ILE F CG1 1 
ATOM   18451 C CG2 . ILE F 1 348 ? -10.966 28.366  60.474  1.00 27.45  ? 348 ILE F CG2 1 
ATOM   18452 C CD1 . ILE F 1 348 ? -12.280 30.046  63.693  1.00 25.65  ? 348 ILE F CD1 1 
ATOM   18453 N N   . TYR F 1 349 ? -13.447 29.639  58.992  1.00 20.64  ? 349 TYR F N   1 
ATOM   18454 C CA  . TYR F 1 349 ? -13.669 30.693  58.005  1.00 20.36  ? 349 TYR F CA  1 
ATOM   18455 C C   . TYR F 1 349 ? -15.116 31.167  58.036  1.00 24.02  ? 349 TYR F C   1 
ATOM   18456 O O   . TYR F 1 349 ? -15.388 32.375  57.995  1.00 19.97  ? 349 TYR F O   1 
ATOM   18457 C CB  . TYR F 1 349 ? -13.333 30.216  56.585  1.00 22.69  ? 349 TYR F CB  1 
ATOM   18458 C CG  . TYR F 1 349 ? -11.956 29.630  56.334  1.00 24.46  ? 349 TYR F CG  1 
ATOM   18459 C CD1 . TYR F 1 349 ? -10.852 29.971  57.114  1.00 22.88  ? 349 TYR F CD1 1 
ATOM   18460 C CD2 . TYR F 1 349 ? -11.770 28.734  55.286  1.00 26.48  ? 349 TYR F CD2 1 
ATOM   18461 C CE1 . TYR F 1 349 ? -9.585  29.395  56.844  1.00 26.88  ? 349 TYR F CE1 1 
ATOM   18462 C CE2 . TYR F 1 349 ? -10.545 28.161  55.014  1.00 25.12  ? 349 TYR F CE2 1 
ATOM   18463 C CZ  . TYR F 1 349 ? -9.452  28.492  55.789  1.00 27.68  ? 349 TYR F CZ  1 
ATOM   18464 O OH  . TYR F 1 349 ? -8.241  27.909  55.471  1.00 34.50  ? 349 TYR F OH  1 
ATOM   18465 N N   . HIS F 1 350 ? -16.058 30.219  58.043  1.00 23.48  ? 350 HIS F N   1 
ATOM   18466 C CA  . HIS F 1 350 ? -17.469 30.571  58.150  1.00 22.75  ? 350 HIS F CA  1 
ATOM   18467 C C   . HIS F 1 350 ? -17.728 31.380  59.409  1.00 20.88  ? 350 HIS F C   1 
ATOM   18468 O O   . HIS F 1 350 ? -18.494 32.345  59.381  1.00 20.62  ? 350 HIS F O   1 
ATOM   18469 C CB  . HIS F 1 350 ? -18.331 29.314  58.131  1.00 19.13  ? 350 HIS F CB  1 
ATOM   18470 C CG  . HIS F 1 350 ? -19.736 29.551  58.561  1.00 21.65  ? 350 HIS F CG  1 
ATOM   18471 N ND1 . HIS F 1 350 ? -20.657 30.192  57.758  1.00 19.83  ? 350 HIS F ND1 1 
ATOM   18472 C CD2 . HIS F 1 350 ? -20.379 29.257  59.718  1.00 20.60  ? 350 HIS F CD2 1 
ATOM   18473 C CE1 . HIS F 1 350 ? -21.811 30.267  58.399  1.00 21.73  ? 350 HIS F CE1 1 
ATOM   18474 N NE2 . HIS F 1 350 ? -21.667 29.716  59.591  1.00 18.78  ? 350 HIS F NE2 1 
ATOM   18475 N N   . THR F 1 351 ? -17.065 31.025  60.513  1.00 19.86  ? 351 THR F N   1 
ATOM   18476 C CA  . THR F 1 351 ? -17.212 31.769  61.766  1.00 23.26  ? 351 THR F CA  1 
ATOM   18477 C C   . THR F 1 351 ? -16.759 33.226  61.629  1.00 21.72  ? 351 THR F C   1 
ATOM   18478 O O   . THR F 1 351 ? -17.495 34.156  61.975  1.00 25.74  ? 351 THR F O   1 
ATOM   18479 C CB  . THR F 1 351 ? -16.409 31.074  62.869  1.00 23.44  ? 351 THR F CB  1 
ATOM   18480 O OG1 . THR F 1 351 ? -16.924 29.756  63.080  1.00 24.01  ? 351 THR F OG1 1 
ATOM   18481 C CG2 . THR F 1 351 ? -16.478 31.875  64.188  1.00 20.37  ? 351 THR F CG2 1 
ATOM   18482 N N   . VAL F 1 352 ? -15.531 33.444  61.164  1.00 21.01  ? 352 VAL F N   1 
ATOM   18483 C CA  . VAL F 1 352 ? -15.020 34.806  61.037  1.00 17.55  ? 352 VAL F CA  1 
ATOM   18484 C C   . VAL F 1 352 ? -15.924 35.619  60.113  1.00 23.46  ? 352 VAL F C   1 
ATOM   18485 O O   . VAL F 1 352 ? -16.201 36.795  60.367  1.00 21.64  ? 352 VAL F O   1 
ATOM   18486 C CB  . VAL F 1 352 ? -13.562 34.770  60.539  1.00 21.21  ? 352 VAL F CB  1 
ATOM   18487 C CG1 . VAL F 1 352 ? -13.060 36.167  60.146  1.00 21.74  ? 352 VAL F CG1 1 
ATOM   18488 C CG2 . VAL F 1 352 ? -12.660 34.172  61.608  1.00 24.36  ? 352 VAL F CG2 1 
ATOM   18489 N N   . ALA F 1 353 ? -16.430 34.989  59.046  1.00 25.65  ? 353 ALA F N   1 
ATOM   18490 C CA  . ALA F 1 353 ? -17.314 35.684  58.115  1.00 21.12  ? 353 ALA F CA  1 
ATOM   18491 C C   . ALA F 1 353 ? -18.574 36.163  58.819  1.00 24.45  ? 353 ALA F C   1 
ATOM   18492 O O   . ALA F 1 353 ? -19.021 37.301  58.621  1.00 23.55  ? 353 ALA F O   1 
ATOM   18493 C CB  . ALA F 1 353 ? -17.665 34.759  56.949  1.00 22.14  ? 353 ALA F CB  1 
ATOM   18494 N N   . GLU F 1 354 ? -19.164 35.301  59.648  1.00 19.95  ? 354 GLU F N   1 
ATOM   18495 C CA  . GLU F 1 354 ? -20.365 35.688  60.379  1.00 26.73  ? 354 GLU F CA  1 
ATOM   18496 C C   . GLU F 1 354 ? -20.094 36.878  61.294  1.00 26.43  ? 354 GLU F C   1 
ATOM   18497 O O   . GLU F 1 354 ? -20.850 37.857  61.303  1.00 21.80  ? 354 GLU F O   1 
ATOM   18498 C CB  . GLU F 1 354 ? -20.884 34.494  61.171  1.00 20.78  ? 354 GLU F CB  1 
ATOM   18499 C CG  . GLU F 1 354 ? -21.612 33.501  60.263  1.00 29.23  ? 354 GLU F CG  1 
ATOM   18500 C CD  . GLU F 1 354 ? -22.715 32.712  60.969  1.00 33.42  ? 354 GLU F CD  1 
ATOM   18501 O OE1 . GLU F 1 354 ? -22.507 32.304  62.130  1.00 30.00  ? 354 GLU F OE1 1 
ATOM   18502 O OE2 . GLU F 1 354 ? -23.775 32.478  60.342  1.00 31.66  ? 354 GLU F OE2 1 
ATOM   18503 N N   . ARG F 1 355 ? -18.988 36.818  62.035  1.00 24.85  ? 355 ARG F N   1 
ATOM   18504 C CA  . ARG F 1 355 ? -18.698 37.796  63.072  1.00 23.34  ? 355 ARG F CA  1 
ATOM   18505 C C   . ARG F 1 355 ? -18.239 39.118  62.483  1.00 28.11  ? 355 ARG F C   1 
ATOM   18506 O O   . ARG F 1 355 ? -18.530 40.176  63.042  1.00 25.37  ? 355 ARG F O   1 
ATOM   18507 C CB  . ARG F 1 355 ? -17.637 37.235  64.008  1.00 23.03  ? 355 ARG F CB  1 
ATOM   18508 C CG  . ARG F 1 355 ? -18.074 35.959  64.680  1.00 22.67  ? 355 ARG F CG  1 
ATOM   18509 C CD  . ARG F 1 355 ? -16.969 35.460  65.584  1.00 32.03  ? 355 ARG F CD  1 
ATOM   18510 N NE  . ARG F 1 355 ? -16.893 36.225  66.820  1.00 26.03  ? 355 ARG F NE  1 
ATOM   18511 C CZ  . ARG F 1 355 ? -16.166 35.870  67.870  1.00 32.65  ? 355 ARG F CZ  1 
ATOM   18512 N NH1 . ARG F 1 355 ? -15.437 34.761  67.864  1.00 28.83  ? 355 ARG F NH1 1 
ATOM   18513 N NH2 . ARG F 1 355 ? -16.151 36.657  68.947  1.00 37.50  ? 355 ARG F NH2 1 
ATOM   18514 N N   . LEU F 1 356 ? -17.514 39.083  61.363  1.00 23.81  ? 356 LEU F N   1 
ATOM   18515 C CA  . LEU F 1 356 ? -17.088 40.317  60.726  1.00 24.61  ? 356 LEU F CA  1 
ATOM   18516 C C   . LEU F 1 356 ? -18.113 40.852  59.741  1.00 27.85  ? 356 LEU F C   1 
ATOM   18517 O O   . LEU F 1 356 ? -18.229 42.074  59.579  1.00 28.10  ? 356 LEU F O   1 
ATOM   18518 C CB  . LEU F 1 356 ? -15.756 40.107  60.001  1.00 25.30  ? 356 LEU F CB  1 
ATOM   18519 C CG  . LEU F 1 356 ? -14.533 39.782  60.855  1.00 30.17  ? 356 LEU F CG  1 
ATOM   18520 C CD1 . LEU F 1 356 ? -13.282 39.673  59.979  1.00 22.83  ? 356 LEU F CD1 1 
ATOM   18521 C CD2 . LEU F 1 356 ? -14.354 40.825  61.999  1.00 30.00  ? 356 LEU F CD2 1 
ATOM   18522 N N   . LEU F 1 357 ? -18.868 39.983  59.067  1.00 27.99  ? 357 LEU F N   1 
ATOM   18523 C CA  . LEU F 1 357 ? -19.725 40.462  57.988  1.00 25.78  ? 357 LEU F CA  1 
ATOM   18524 C C   . LEU F 1 357 ? -21.213 40.388  58.300  1.00 28.36  ? 357 LEU F C   1 
ATOM   18525 O O   . LEU F 1 357 ? -21.991 41.105  57.662  1.00 28.85  ? 357 LEU F O   1 
ATOM   18526 C CB  . LEU F 1 357 ? -19.450 39.678  56.699  1.00 25.65  ? 357 LEU F CB  1 
ATOM   18527 C CG  . LEU F 1 357 ? -18.004 39.622  56.170  1.00 28.81  ? 357 LEU F CG  1 
ATOM   18528 C CD1 . LEU F 1 357 ? -17.978 38.962  54.812  1.00 23.97  ? 357 LEU F CD1 1 
ATOM   18529 C CD2 . LEU F 1 357 ? -17.348 40.989  56.096  1.00 28.56  ? 357 LEU F CD2 1 
ATOM   18530 N N   . GLY F 1 358 ? -21.623 39.575  59.263  1.00 26.46  ? 358 GLY F N   1 
ATOM   18531 C CA  . GLY F 1 358 ? -23.025 39.382  59.575  1.00 27.96  ? 358 GLY F CA  1 
ATOM   18532 C C   . GLY F 1 358 ? -23.506 37.991  59.188  1.00 32.66  ? 358 GLY F C   1 
ATOM   18533 O O   . GLY F 1 358 ? -22.843 37.236  58.473  1.00 25.60  ? 358 GLY F O   1 
ATOM   18534 N N   . HIS F 1 359 ? -24.710 37.675  59.660  1.00 29.29  ? 359 HIS F N   1 
ATOM   18535 C CA  . HIS F 1 359 ? -25.156 36.290  59.648  1.00 35.96  ? 359 HIS F CA  1 
ATOM   18536 C C   . HIS F 1 359 ? -25.642 35.794  58.293  1.00 35.81  ? 359 HIS F C   1 
ATOM   18537 O O   . HIS F 1 359 ? -25.820 34.582  58.135  1.00 43.46  ? 359 HIS F O   1 
ATOM   18538 C CB  . HIS F 1 359 ? -26.251 36.070  60.696  1.00 33.72  ? 359 HIS F CB  1 
ATOM   18539 C CG  . HIS F 1 359 ? -25.710 35.754  62.052  1.00 42.61  ? 359 HIS F CG  1 
ATOM   18540 N ND1 . HIS F 1 359 ? -25.356 34.477  62.428  1.00 45.11  ? 359 HIS F ND1 1 
ATOM   18541 C CD2 . HIS F 1 359 ? -25.446 36.548  63.116  1.00 48.74  ? 359 HIS F CD2 1 
ATOM   18542 C CE1 . HIS F 1 359 ? -24.896 34.498  63.667  1.00 51.11  ? 359 HIS F CE1 1 
ATOM   18543 N NE2 . HIS F 1 359 ? -24.939 35.743  64.107  1.00 49.77  ? 359 HIS F NE2 1 
ATOM   18544 N N   . ASP F 1 360 ? -25.857 36.653  57.306  1.00 33.90  ? 360 ASP F N   1 
ATOM   18545 C CA  . ASP F 1 360 ? -26.223 36.135  55.991  1.00 30.06  ? 360 ASP F CA  1 
ATOM   18546 C C   . ASP F 1 360 ? -25.179 36.509  54.941  1.00 28.76  ? 360 ASP F C   1 
ATOM   18547 O O   . ASP F 1 360 ? -25.504 36.699  53.766  1.00 29.33  ? 360 ASP F O   1 
ATOM   18548 C CB  . ASP F 1 360 ? -27.618 36.625  55.597  1.00 37.45  ? 360 ASP F CB  1 
ATOM   18549 C CG  . ASP F 1 360 ? -28.728 35.790  56.237  1.00 38.47  ? 360 ASP F CG  1 
ATOM   18550 O OD1 . ASP F 1 360 ? -28.831 34.564  55.964  1.00 32.91  ? 360 ASP F OD1 1 
ATOM   18551 O OD2 . ASP F 1 360 ? -29.464 36.365  57.067  1.00 36.56  ? 360 ASP F OD2 1 
ATOM   18552 N N   . TYR F 1 361 ? -23.907 36.561  55.362  1.00 25.24  ? 361 TYR F N   1 
ATOM   18553 C CA  . TYR F 1 361 ? -22.836 37.093  54.526  1.00 23.54  ? 361 TYR F CA  1 
ATOM   18554 C C   . TYR F 1 361 ? -22.771 36.416  53.158  1.00 26.09  ? 361 TYR F C   1 
ATOM   18555 O O   . TYR F 1 361 ? -22.385 37.053  52.168  1.00 25.34  ? 361 TYR F O   1 
ATOM   18556 C CB  . TYR F 1 361 ? -21.494 36.931  55.250  1.00 25.00  ? 361 TYR F CB  1 
ATOM   18557 C CG  . TYR F 1 361 ? -21.064 35.480  55.362  1.00 24.70  ? 361 TYR F CG  1 
ATOM   18558 C CD1 . TYR F 1 361 ? -20.315 34.864  54.352  1.00 22.30  ? 361 TYR F CD1 1 
ATOM   18559 C CD2 . TYR F 1 361 ? -21.430 34.716  56.460  1.00 22.02  ? 361 TYR F CD2 1 
ATOM   18560 C CE1 . TYR F 1 361 ? -19.942 33.536  54.453  1.00 19.84  ? 361 TYR F CE1 1 
ATOM   18561 C CE2 . TYR F 1 361 ? -21.057 33.385  56.565  1.00 21.03  ? 361 TYR F CE2 1 
ATOM   18562 C CZ  . TYR F 1 361 ? -20.323 32.804  55.562  1.00 20.95  ? 361 TYR F CZ  1 
ATOM   18563 O OH  . TYR F 1 361 ? -19.968 31.483  55.682  1.00 24.60  ? 361 TYR F OH  1 
ATOM   18564 N N   . ALA F 1 362 ? -23.132 35.126  53.072  1.00 24.87  ? 362 ALA F N   1 
ATOM   18565 C CA  . ALA F 1 362 ? -22.878 34.403  51.824  1.00 23.00  ? 362 ALA F CA  1 
ATOM   18566 C C   . ALA F 1 362 ? -23.803 34.851  50.706  1.00 25.17  ? 362 ALA F C   1 
ATOM   18567 O O   . ALA F 1 362 ? -23.501 34.620  49.534  1.00 28.39  ? 362 ALA F O   1 
ATOM   18568 C CB  . ALA F 1 362 ? -22.988 32.893  52.027  1.00 25.55  ? 362 ALA F CB  1 
ATOM   18569 N N   . ARG F 1 363 ? -24.885 35.547  51.023  1.00 25.92  ? 363 ARG F N   1 
ATOM   18570 C CA  . ARG F 1 363 ? -25.687 36.080  49.937  1.00 28.38  ? 363 ARG F CA  1 
ATOM   18571 C C   . ARG F 1 363 ? -25.043 37.286  49.273  1.00 29.56  ? 363 ARG F C   1 
ATOM   18572 O O   . ARG F 1 363 ? -25.369 37.583  48.122  1.00 30.20  ? 363 ARG F O   1 
ATOM   18573 C CB  . ARG F 1 363 ? -27.073 36.428  50.447  1.00 29.70  ? 363 ARG F CB  1 
ATOM   18574 C CG  . ARG F 1 363 ? -27.878 35.185  50.684  1.00 33.36  ? 363 ARG F CG  1 
ATOM   18575 C CD  . ARG F 1 363 ? -28.917 35.394  51.728  1.00 33.75  ? 363 ARG F CD  1 
ATOM   18576 N NE  . ARG F 1 363 ? -29.668 34.165  51.933  1.00 30.84  ? 363 ARG F NE  1 
ATOM   18577 C CZ  . ARG F 1 363 ? -30.824 34.111  52.576  1.00 37.29  ? 363 ARG F CZ  1 
ATOM   18578 N NH1 . ARG F 1 363 ? -31.377 35.204  53.092  1.00 34.22  ? 363 ARG F NH1 1 
ATOM   18579 N NH2 . ARG F 1 363 ? -31.440 32.936  52.707  1.00 28.28  ? 363 ARG F NH2 1 
ATOM   18580 N N   . ASN F 1 364 ? -24.128 37.977  49.954  1.00 26.86  ? 364 ASN F N   1 
ATOM   18581 C CA  . ASN F 1 364 ? -23.592 39.222  49.434  1.00 26.72  ? 364 ASN F CA  1 
ATOM   18582 C C   . ASN F 1 364 ? -22.078 39.288  49.406  1.00 32.10  ? 364 ASN F C   1 
ATOM   18583 O O   . ASN F 1 364 ? -21.533 40.288  48.924  1.00 31.95  ? 364 ASN F O   1 
ATOM   18584 C CB  . ASN F 1 364 ? -24.128 40.400  50.252  1.00 33.25  ? 364 ASN F CB  1 
ATOM   18585 C CG  . ASN F 1 364 ? -25.591 40.240  50.567  1.00 40.42  ? 364 ASN F CG  1 
ATOM   18586 O OD1 . ASN F 1 364 ? -26.423 40.305  49.666  1.00 34.67  ? 364 ASN F OD1 1 
ATOM   18587 N ND2 . ASN F 1 364 ? -25.914 39.974  51.839  1.00 38.82  ? 364 ASN F ND2 1 
ATOM   18588 N N   . ASN F 1 365 ? -21.387 38.273  49.917  1.00 28.33  ? 365 ASN F N   1 
ATOM   18589 C CA  . ASN F 1 365 ? -19.947 38.326  50.044  1.00 29.90  ? 365 ASN F CA  1 
ATOM   18590 C C   . ASN F 1 365 ? -19.350 37.011  49.588  1.00 28.46  ? 365 ASN F C   1 
ATOM   18591 O O   . ASN F 1 365 ? -20.041 35.996  49.490  1.00 25.66  ? 365 ASN F O   1 
ATOM   18592 C CB  . ASN F 1 365 ? -19.528 38.604  51.480  1.00 26.12  ? 365 ASN F CB  1 
ATOM   18593 C CG  . ASN F 1 365 ? -20.090 39.901  51.997  1.00 30.39  ? 365 ASN F CG  1 
ATOM   18594 O OD1 . ASN F 1 365 ? -19.441 40.946  51.915  1.00 24.47  ? 365 ASN F OD1 1 
ATOM   18595 N ND2 . ASN F 1 365 ? -21.315 39.849  52.514  1.00 24.65  ? 365 ASN F ND2 1 
ATOM   18596 N N   . PHE F 1 366 ? -18.042 37.048  49.332  1.00 23.52  ? 366 PHE F N   1 
ATOM   18597 C CA  . PHE F 1 366 ? -17.242 35.880  49.028  1.00 24.43  ? 366 PHE F CA  1 
ATOM   18598 C C   . PHE F 1 366 ? -16.033 35.865  49.948  1.00 22.39  ? 366 PHE F C   1 
ATOM   18599 O O   . PHE F 1 366 ? -15.538 36.912  50.362  1.00 22.53  ? 366 PHE F O   1 
ATOM   18600 C CB  . PHE F 1 366 ? -16.762 35.877  47.567  1.00 27.82  ? 366 PHE F CB  1 
ATOM   18601 C CG  . PHE F 1 366 ? -17.855 36.108  46.566  1.00 28.65  ? 366 PHE F CG  1 
ATOM   18602 C CD1 . PHE F 1 366 ? -18.265 37.401  46.253  1.00 32.22  ? 366 PHE F CD1 1 
ATOM   18603 C CD2 . PHE F 1 366 ? -18.460 35.038  45.921  1.00 29.47  ? 366 PHE F CD2 1 
ATOM   18604 C CE1 . PHE F 1 366 ? -19.273 37.625  45.323  1.00 33.07  ? 366 PHE F CE1 1 
ATOM   18605 C CE2 . PHE F 1 366 ? -19.470 35.248  44.981  1.00 31.85  ? 366 PHE F CE2 1 
ATOM   18606 C CZ  . PHE F 1 366 ? -19.884 36.545  44.687  1.00 29.16  ? 366 PHE F CZ  1 
ATOM   18607 N N   . PHE F 1 367 ? -15.557 34.673  50.272  1.00 22.71  ? 367 PHE F N   1 
ATOM   18608 C CA  . PHE F 1 367 ? -14.277 34.578  50.931  1.00 24.06  ? 367 PHE F CA  1 
ATOM   18609 C C   . PHE F 1 367 ? -13.489 33.438  50.318  1.00 31.02  ? 367 PHE F C   1 
ATOM   18610 O O   . PHE F 1 367 ? -14.018 32.589  49.597  1.00 27.09  ? 367 PHE F O   1 
ATOM   18611 C CB  . PHE F 1 367 ? -14.393 34.472  52.474  1.00 21.06  ? 367 PHE F CB  1 
ATOM   18612 C CG  . PHE F 1 367 ? -14.848 33.125  53.023  1.00 25.19  ? 367 PHE F CG  1 
ATOM   18613 C CD1 . PHE F 1 367 ? -14.062 31.989  52.923  1.00 22.15  ? 367 PHE F CD1 1 
ATOM   18614 C CD2 . PHE F 1 367 ? -16.030 33.049  53.772  1.00 26.65  ? 367 PHE F CD2 1 
ATOM   18615 C CE1 . PHE F 1 367 ? -14.474 30.787  53.486  1.00 28.39  ? 367 PHE F CE1 1 
ATOM   18616 C CE2 . PHE F 1 367 ? -16.468 31.856  54.331  1.00 24.42  ? 367 PHE F CE2 1 
ATOM   18617 C CZ  . PHE F 1 367 ? -15.690 30.718  54.202  1.00 27.69  ? 367 PHE F CZ  1 
ATOM   18618 N N   . SER F 1 368 ? -12.195 33.466  50.602  1.00 24.44  ? 368 SER F N   1 
ATOM   18619 C CA  . SER F 1 368 ? -11.233 32.577  49.985  1.00 28.71  ? 368 SER F CA  1 
ATOM   18620 C C   . SER F 1 368 ? -10.004 32.648  50.867  1.00 27.85  ? 368 SER F C   1 
ATOM   18621 O O   . SER F 1 368 ? -9.601  33.745  51.277  1.00 28.69  ? 368 SER F O   1 
ATOM   18622 C CB  . SER F 1 368 ? -10.927 33.005  48.543  1.00 32.32  ? 368 SER F CB  1 
ATOM   18623 O OG  . SER F 1 368 ? -10.132 32.048  47.864  1.00 32.33  ? 368 SER F OG  1 
ATOM   18624 N N   . SER F 1 369 ? -9.466  31.490  51.217  1.00 26.49  ? 369 SER F N   1 
ATOM   18625 C CA  . SER F 1 369 ? -8.292  31.399  52.067  1.00 29.49  ? 369 SER F CA  1 
ATOM   18626 C C   . SER F 1 369 ? -7.057  31.129  51.215  1.00 27.92  ? 369 SER F C   1 
ATOM   18627 O O   . SER F 1 369 ? -7.148  30.589  50.112  1.00 28.57  ? 369 SER F O   1 
ATOM   18628 C CB  . SER F 1 369 ? -8.454  30.299  53.124  1.00 28.12  ? 369 SER F CB  1 
ATOM   18629 O OG  . SER F 1 369 ? -8.374  29.007  52.550  1.00 28.46  ? 369 SER F OG  1 
ATOM   18630 N N   . ILE F 1 370 ? -5.909  31.557  51.731  1.00 35.14  ? 370 ILE F N   1 
ATOM   18631 C CA  . ILE F 1 370 ? -4.593  31.296  51.157  1.00 30.59  ? 370 ILE F CA  1 
ATOM   18632 C C   . ILE F 1 370 ? -3.774  30.600  52.237  1.00 33.79  ? 370 ILE F C   1 
ATOM   18633 O O   . ILE F 1 370 ? -3.541  31.170  53.317  1.00 26.63  ? 370 ILE F O   1 
ATOM   18634 C CB  . ILE F 1 370 ? -3.894  32.585  50.692  1.00 29.33  ? 370 ILE F CB  1 
ATOM   18635 C CG1 . ILE F 1 370 ? -4.861  33.472  49.913  1.00 31.47  ? 370 ILE F CG1 1 
ATOM   18636 C CG2 . ILE F 1 370 ? -2.670  32.256  49.808  1.00 28.81  ? 370 ILE F CG2 1 
ATOM   18637 C CD1 . ILE F 1 370 ? -4.233  34.764  49.421  1.00 31.38  ? 370 ILE F CD1 1 
ATOM   18638 N N   . LEU F 1 371 ? -3.356  29.364  51.966  1.00 32.21  ? 371 LEU F N   1 
ATOM   18639 C CA  . LEU F 1 371 ? -2.573  28.620  52.940  1.00 34.53  ? 371 LEU F CA  1 
ATOM   18640 C C   . LEU F 1 371 ? -1.085  28.754  52.695  1.00 31.80  ? 371 LEU F C   1 
ATOM   18641 O O   . LEU F 1 371 ? -0.289  28.301  53.519  1.00 28.77  ? 371 LEU F O   1 
ATOM   18642 C CB  . LEU F 1 371 ? -2.979  27.153  52.913  1.00 32.88  ? 371 LEU F CB  1 
ATOM   18643 C CG  . LEU F 1 371 ? -4.461  27.007  52.592  1.00 37.82  ? 371 LEU F CG  1 
ATOM   18644 C CD1 . LEU F 1 371 ? -4.735  25.592  52.136  1.00 41.24  ? 371 LEU F CD1 1 
ATOM   18645 C CD2 . LEU F 1 371 ? -5.291  27.375  53.833  1.00 34.53  ? 371 LEU F CD2 1 
ATOM   18646 N N   . ASN F 1 372 ? -0.720  29.464  51.629  1.00 36.19  ? 372 ASN F N   1 
ATOM   18647 C CA  . ASN F 1 372 ? 0.515   29.331  50.874  1.00 36.40  ? 372 ASN F CA  1 
ATOM   18648 C C   . ASN F 1 372 ? 1.554   30.384  51.202  1.00 38.42  ? 372 ASN F C   1 
ATOM   18649 O O   . ASN F 1 372 ? 2.666   30.317  50.662  1.00 38.22  ? 372 ASN F O   1 
ATOM   18650 C CB  . ASN F 1 372 ? 0.189   29.454  49.384  1.00 27.90  ? 372 ASN F CB  1 
ATOM   18651 C CG  . ASN F 1 372 ? 0.687   28.305  48.592  1.00 41.66  ? 372 ASN F CG  1 
ATOM   18652 O OD1 . ASN F 1 372 ? 1.718   27.727  48.913  1.00 44.83  ? 372 ASN F OD1 1 
ATOM   18653 N ND2 . ASN F 1 372 ? -0.057  27.934  47.552  1.00 48.74  ? 372 ASN F ND2 1 
ATOM   18654 N N   . VAL F 1 373 ? 1.206   31.372  52.012  1.00 31.65  ? 373 VAL F N   1 
ATOM   18655 C CA  . VAL F 1 373 ? 1.962   32.616  52.077  1.00 33.87  ? 373 VAL F CA  1 
ATOM   18656 C C   . VAL F 1 373 ? 3.246   32.381  52.857  1.00 33.54  ? 373 VAL F C   1 
ATOM   18657 O O   . VAL F 1 373 ? 3.272   31.614  53.827  1.00 31.03  ? 373 VAL F O   1 
ATOM   18658 C CB  . VAL F 1 373 ? 1.097   33.730  52.701  1.00 33.61  ? 373 VAL F CB  1 
ATOM   18659 C CG1 . VAL F 1 373 ? 1.960   34.828  53.324  1.00 33.95  ? 373 VAL F CG1 1 
ATOM   18660 C CG2 . VAL F 1 373 ? 0.151   34.316  51.658  1.00 27.23  ? 373 VAL F CG2 1 
ATOM   18661 N N   . VAL F 1 374 ? 4.320   33.039  52.429  1.00 32.23  ? 374 VAL F N   1 
ATOM   18662 C CA  . VAL F 1 374 ? 5.634   32.859  53.046  1.00 32.47  ? 374 VAL F CA  1 
ATOM   18663 C C   . VAL F 1 374 ? 5.560   33.124  54.545  1.00 32.98  ? 374 VAL F C   1 
ATOM   18664 O O   . VAL F 1 374 ? 5.179   34.230  54.961  1.00 29.57  ? 374 VAL F O   1 
ATOM   18665 C CB  . VAL F 1 374 ? 6.689   33.757  52.384  1.00 27.15  ? 374 VAL F CB  1 
ATOM   18666 C CG1 . VAL F 1 374 ? 7.977   33.680  53.168  1.00 25.69  ? 374 VAL F CG1 1 
ATOM   18667 C CG2 . VAL F 1 374 ? 6.895   33.314  50.969  1.00 26.25  ? 374 VAL F CG2 1 
ATOM   18668 N N   . PRO F 1 375 ? 5.911   32.140  55.376  1.00 25.96  ? 375 PRO F N   1 
ATOM   18669 C CA  . PRO F 1 375 ? 5.825   32.306  56.837  1.00 25.47  ? 375 PRO F CA  1 
ATOM   18670 C C   . PRO F 1 375 ? 6.560   33.542  57.326  1.00 27.60  ? 375 PRO F C   1 
ATOM   18671 O O   . PRO F 1 375 ? 7.735   33.745  57.033  1.00 36.59  ? 375 PRO F O   1 
ATOM   18672 C CB  . PRO F 1 375 ? 6.487   31.030  57.365  1.00 30.93  ? 375 PRO F CB  1 
ATOM   18673 C CG  . PRO F 1 375 ? 6.256   30.004  56.270  1.00 29.47  ? 375 PRO F CG  1 
ATOM   18674 C CD  . PRO F 1 375 ? 6.329   30.781  54.983  1.00 30.18  ? 375 PRO F CD  1 
ATOM   18675 N N   . ALA F 1 376 ? 5.873   34.369  58.094  1.00 29.83  ? 376 ALA F N   1 
ATOM   18676 C CA  . ALA F 1 376 ? 6.544   35.550  58.612  1.00 37.11  ? 376 ALA F CA  1 
ATOM   18677 C C   . ALA F 1 376 ? 5.894   35.923  59.926  1.00 27.36  ? 376 ALA F C   1 
ATOM   18678 O O   . ALA F 1 376 ? 4.795   35.464  60.240  1.00 32.30  ? 376 ALA F O   1 
ATOM   18679 C CB  . ALA F 1 376 ? 6.504   36.719  57.611  1.00 34.84  ? 376 ALA F CB  1 
ATOM   18680 N N   . GLY F 1 377 ? 6.599   36.735  60.708  1.00 30.15  ? 377 GLY F N   1 
ATOM   18681 C CA  . GLY F 1 377 ? 6.042   37.215  61.952  1.00 28.77  ? 377 GLY F CA  1 
ATOM   18682 C C   . GLY F 1 377 ? 4.785   37.970  61.588  1.00 33.88  ? 377 GLY F C   1 
ATOM   18683 O O   . GLY F 1 377 ? 4.669   38.485  60.472  1.00 32.03  ? 377 GLY F O   1 
ATOM   18684 N N   . LEU F 1 378 ? 3.822   38.031  62.490  1.00 31.13  ? 378 LEU F N   1 
ATOM   18685 C CA  . LEU F 1 378 ? 2.562   38.695  62.184  1.00 39.30  ? 378 LEU F CA  1 
ATOM   18686 C C   . LEU F 1 378 ? 2.713   40.106  61.565  1.00 37.45  ? 378 LEU F C   1 
ATOM   18687 O O   . LEU F 1 378 ? 1.771   40.886  61.657  1.00 27.53  ? 378 LEU F O   1 
ATOM   18688 C CB  . LEU F 1 378 ? 1.739   38.699  63.484  1.00 29.10  ? 378 LEU F CB  1 
ATOM   18689 C CG  . LEU F 1 378 ? 0.386   39.407  63.737  1.00 25.84  ? 378 LEU F CG  1 
ATOM   18690 C CD1 . LEU F 1 378 ? -0.732  38.663  63.037  1.00 23.91  ? 378 LEU F CD1 1 
ATOM   18691 C CD2 . LEU F 1 378 ? 0.063   39.526  65.196  1.00 29.68  ? 378 LEU F CD2 1 
ATOM   18692 N N   . ALA F 1 379 ? 3.848   40.431  60.892  1.00 46.31  ? 379 ALA F N   1 
ATOM   18693 C CA  . ALA F 1 379 ? 4.443   41.768  60.959  1.00 40.10  ? 379 ALA F CA  1 
ATOM   18694 C C   . ALA F 1 379 ? 4.457   42.413  59.588  1.00 46.51  ? 379 ALA F C   1 
ATOM   18695 O O   . ALA F 1 379 ? 3.419   42.969  59.168  1.00 49.52  ? 379 ALA F O   1 
ATOM   18696 C CB  . ALA F 1 379 ? 5.880   41.723  61.474  1.00 46.58  ? 379 ALA F CB  1 
ATOM   18697 N N   . ASP F 1 380 ? 5.600   42.487  58.937  1.00 50.63  ? 380 ASP F N   1 
ATOM   18698 C CA  . ASP F 1 380 ? 5.740   41.718  57.725  1.00 49.32  ? 380 ASP F CA  1 
ATOM   18699 C C   . ASP F 1 380 ? 4.354   41.238  57.293  1.00 39.17  ? 380 ASP F C   1 
ATOM   18700 O O   . ASP F 1 380 ? 3.849   41.705  56.278  1.00 41.20  ? 380 ASP F O   1 
ATOM   18701 C CB  . ASP F 1 380 ? 6.732   40.569  58.015  1.00 47.57  ? 380 ASP F CB  1 
ATOM   18702 C CG  . ASP F 1 380 ? 7.816   40.986  59.073  1.00 53.13  ? 380 ASP F CG  1 
ATOM   18703 O OD1 . ASP F 1 380 ? 8.219   42.167  59.092  1.00 51.99  ? 380 ASP F OD1 1 
ATOM   18704 O OD2 . ASP F 1 380 ? 8.242   40.163  59.924  1.00 50.59  ? 380 ASP F OD2 1 
ATOM   18705 N N   . LEU F 1 381 ? 3.699   40.361  58.072  1.00 40.04  ? 381 LEU F N   1 
ATOM   18706 C CA  . LEU F 1 381 ? 2.381   39.858  57.687  1.00 38.43  ? 381 LEU F CA  1 
ATOM   18707 C C   . LEU F 1 381 ? 1.342   40.977  57.667  1.00 28.91  ? 381 LEU F C   1 
ATOM   18708 O O   . LEU F 1 381 ? 0.805   41.313  56.608  1.00 29.38  ? 381 LEU F O   1 
ATOM   18709 C CB  . LEU F 1 381 ? 1.970   38.715  58.610  1.00 30.72  ? 381 LEU F CB  1 
ATOM   18710 C CG  . LEU F 1 381 ? 1.796   37.384  57.880  1.00 35.20  ? 381 LEU F CG  1 
ATOM   18711 C CD1 . LEU F 1 381 ? 2.793   37.251  56.748  1.00 30.57  ? 381 LEU F CD1 1 
ATOM   18712 C CD2 . LEU F 1 381 ? 1.920   36.222  58.837  1.00 33.10  ? 381 LEU F CD2 1 
ATOM   18713 N N   . LEU F 1 382 ? 1.072   41.606  58.812  1.00 27.26  ? 382 LEU F N   1 
ATOM   18714 C CA  . LEU F 1 382 ? 0.119   42.718  58.788  1.00 30.66  ? 382 LEU F CA  1 
ATOM   18715 C C   . LEU F 1 382 ? 0.625   43.869  57.923  1.00 31.78  ? 382 LEU F C   1 
ATOM   18716 O O   . LEU F 1 382 ? -0.152  44.477  57.172  1.00 30.46  ? 382 LEU F O   1 
ATOM   18717 C CB  . LEU F 1 382 ? -0.180  43.207  60.196  1.00 25.32  ? 382 LEU F CB  1 
ATOM   18718 C CG  . LEU F 1 382 ? -1.082  42.232  60.930  1.00 25.46  ? 382 LEU F CG  1 
ATOM   18719 C CD1 . LEU F 1 382 ? -1.396  42.717  62.326  1.00 24.13  ? 382 LEU F CD1 1 
ATOM   18720 C CD2 . LEU F 1 382 ? -2.349  41.974  60.108  1.00 23.98  ? 382 LEU F CD2 1 
ATOM   18721 N N   . ARG F 1 383 ? 1.935   44.152  57.980  1.00 34.93  ? 383 ARG F N   1 
ATOM   18722 C CA  . ARG F 1 383 ? 2.494   45.272  57.218  1.00 34.22  ? 383 ARG F CA  1 
ATOM   18723 C C   . ARG F 1 383 ? 2.422   45.015  55.722  1.00 27.73  ? 383 ARG F C   1 
ATOM   18724 O O   . ARG F 1 383 ? 2.136   45.936  54.949  1.00 29.28  ? 383 ARG F O   1 
ATOM   18725 C CB  . ARG F 1 383 ? 3.939   45.551  57.652  1.00 31.90  ? 383 ARG F CB  1 
ATOM   18726 C CG  . ARG F 1 383 ? 4.590   46.713  56.932  1.00 30.54  ? 383 ARG F CG  1 
ATOM   18727 C CD  . ARG F 1 383 ? 4.382   48.016  57.683  1.00 30.18  ? 383 ARG F CD  1 
ATOM   18728 N NE  . ARG F 1 383 ? 3.087   48.658  57.449  1.00 27.75  ? 383 ARG F NE  1 
ATOM   18729 C CZ  . ARG F 1 383 ? 2.763   49.387  56.387  1.00 30.01  ? 383 ARG F CZ  1 
ATOM   18730 N NH1 . ARG F 1 383 ? 3.584   49.517  55.358  1.00 31.87  ? 383 ARG F NH1 1 
ATOM   18731 N NH2 . ARG F 1 383 ? 1.591   50.025  56.371  1.00 27.67  ? 383 ARG F NH2 1 
ATOM   18732 N N   . SER F 1 384 ? 2.689   43.776  55.290  1.00 28.68  ? 384 SER F N   1 
ATOM   18733 C CA  . SER F 1 384 ? 2.479   43.428  53.886  1.00 23.49  ? 384 SER F CA  1 
ATOM   18734 C C   . SER F 1 384 ? 1.016   43.577  53.499  1.00 27.80  ? 384 SER F C   1 
ATOM   18735 O O   . SER F 1 384 ? 0.706   43.994  52.377  1.00 28.14  ? 384 SER F O   1 
ATOM   18736 C CB  . SER F 1 384 ? 2.939   42.004  53.602  1.00 25.39  ? 384 SER F CB  1 
ATOM   18737 O OG  . SER F 1 384 ? 4.307   41.846  53.936  1.00 32.54  ? 384 SER F OG  1 
ATOM   18738 N N   . LEU F 1 385 ? 0.098   43.227  54.409  1.00 26.75  ? 385 LEU F N   1 
ATOM   18739 C CA  . LEU F 1 385 ? -1.318  43.445  54.122  1.00 30.89  ? 385 LEU F CA  1 
ATOM   18740 C C   . LEU F 1 385 ? -1.618  44.938  54.010  1.00 27.36  ? 385 LEU F C   1 
ATOM   18741 O O   . LEU F 1 385 ? -2.299  45.377  53.077  1.00 27.13  ? 385 LEU F O   1 
ATOM   18742 C CB  . LEU F 1 385 ? -2.200  42.781  55.187  1.00 23.92  ? 385 LEU F CB  1 
ATOM   18743 C CG  . LEU F 1 385 ? -2.226  41.237  55.292  1.00 29.49  ? 385 LEU F CG  1 
ATOM   18744 C CD1 . LEU F 1 385 ? -3.337  40.784  56.249  1.00 24.48  ? 385 LEU F CD1 1 
ATOM   18745 C CD2 . LEU F 1 385 ? -2.403  40.565  53.926  1.00 22.76  ? 385 LEU F CD2 1 
ATOM   18746 N N   . GLU F 1 386 ? -1.093  45.740  54.932  1.00 26.82  ? 386 GLU F N   1 
ATOM   18747 C CA  . GLU F 1 386 ? -1.227  47.184  54.769  1.00 29.28  ? 386 GLU F CA  1 
ATOM   18748 C C   . GLU F 1 386 ? -0.547  47.649  53.491  1.00 30.77  ? 386 GLU F C   1 
ATOM   18749 O O   . GLU F 1 386 ? -1.138  48.404  52.705  1.00 30.24  ? 386 GLU F O   1 
ATOM   18750 C CB  . GLU F 1 386 ? -0.665  47.904  55.985  1.00 28.68  ? 386 GLU F CB  1 
ATOM   18751 C CG  . GLU F 1 386 ? -1.504  47.663  57.224  1.00 26.04  ? 386 GLU F CG  1 
ATOM   18752 C CD  . GLU F 1 386 ? -1.127  48.541  58.395  1.00 31.73  ? 386 GLU F CD  1 
ATOM   18753 O OE1 . GLU F 1 386 ? -0.886  49.766  58.209  1.00 29.14  ? 386 GLU F OE1 1 
ATOM   18754 O OE2 . GLU F 1 386 ? -1.071  47.988  59.516  1.00 30.40  ? 386 GLU F OE2 1 
ATOM   18755 N N   . ARG F 1 387 ? 0.676   47.164  53.238  1.00 27.38  ? 387 ARG F N   1 
ATOM   18756 C CA  . ARG F 1 387 ? 1.382   47.546  52.016  1.00 30.28  ? 387 ARG F CA  1 
ATOM   18757 C C   . ARG F 1 387 ? 0.559   47.216  50.776  1.00 29.20  ? 387 ARG F C   1 
ATOM   18758 O O   . ARG F 1 387 ? 0.521   47.996  49.819  1.00 30.28  ? 387 ARG F O   1 
ATOM   18759 C CB  . ARG F 1 387 ? 2.753   46.856  51.946  1.00 31.36  ? 387 ARG F CB  1 
ATOM   18760 C CG  . ARG F 1 387 ? 3.577   47.231  50.705  1.00 29.90  ? 387 ARG F CG  1 
ATOM   18761 C CD  . ARG F 1 387 ? 4.849   46.390  50.592  1.00 32.69  ? 387 ARG F CD  1 
ATOM   18762 N NE  . ARG F 1 387 ? 5.525   46.305  51.876  1.00 31.44  ? 387 ARG F NE  1 
ATOM   18763 C CZ  . ARG F 1 387 ? 5.784   45.181  52.531  1.00 35.02  ? 387 ARG F CZ  1 
ATOM   18764 N NH1 . ARG F 1 387 ? 5.519   43.994  52.010  1.00 32.99  ? 387 ARG F NH1 1 
ATOM   18765 N NH2 . ARG F 1 387 ? 6.311   45.251  53.751  1.00 36.46  ? 387 ARG F NH2 1 
ATOM   18766 N N   . ALA F 1 388 ? -0.119  46.072  50.781  1.00 28.23  ? 388 ALA F N   1 
ATOM   18767 C CA  . ALA F 1 388 ? -0.889  45.644  49.620  1.00 33.40  ? 388 ALA F CA  1 
ATOM   18768 C C   . ALA F 1 388 ? -2.209  46.393  49.453  1.00 29.50  ? 388 ALA F C   1 
ATOM   18769 O O   . ALA F 1 388 ? -2.867  46.226  48.425  1.00 32.20  ? 388 ALA F O   1 
ATOM   18770 C CB  . ALA F 1 388 ? -1.158  44.137  49.711  1.00 27.09  ? 388 ALA F CB  1 
ATOM   18771 N N   . GLY F 1 389 ? -2.624  47.185  50.435  1.00 27.47  ? 389 GLY F N   1 
ATOM   18772 C CA  . GLY F 1 389 ? -3.907  47.848  50.369  1.00 31.31  ? 389 GLY F CA  1 
ATOM   18773 C C   . GLY F 1 389 ? -5.092  47.020  50.818  1.00 33.34  ? 389 GLY F C   1 
ATOM   18774 O O   . GLY F 1 389 ? -6.233  47.410  50.548  1.00 23.23  ? 389 GLY F O   1 
ATOM   18775 N N   . VAL F 1 390 ? -4.867  45.891  51.505  1.00 30.57  ? 390 VAL F N   1 
ATOM   18776 C CA  . VAL F 1 390 ? -5.923  44.892  51.676  1.00 28.29  ? 390 VAL F CA  1 
ATOM   18777 C C   . VAL F 1 390 ? -6.048  44.362  53.102  1.00 29.34  ? 390 VAL F C   1 
ATOM   18778 O O   . VAL F 1 390 ? -6.670  43.319  53.321  1.00 24.84  ? 390 VAL F O   1 
ATOM   18779 C CB  . VAL F 1 390 ? -5.707  43.706  50.712  1.00 28.66  ? 390 VAL F CB  1 
ATOM   18780 C CG1 . VAL F 1 390 ? -5.633  44.188  49.269  1.00 27.79  ? 390 VAL F CG1 1 
ATOM   18781 C CG2 . VAL F 1 390 ? -4.456  42.946  51.089  1.00 24.80  ? 390 VAL F CG2 1 
ATOM   18782 N N   . ARG F 1 391 ? -5.474  45.042  54.089  1.00 28.27  ? 391 ARG F N   1 
ATOM   18783 C CA  . ARG F 1 391 ? -5.695  44.587  55.454  1.00 25.71  ? 391 ARG F CA  1 
ATOM   18784 C C   . ARG F 1 391 ? -7.166  44.784  55.791  1.00 30.92  ? 391 ARG F C   1 
ATOM   18785 O O   . ARG F 1 391 ? -7.733  45.847  55.499  1.00 26.84  ? 391 ARG F O   1 
ATOM   18786 C CB  . ARG F 1 391 ? -4.811  45.342  56.439  1.00 26.31  ? 391 ARG F CB  1 
ATOM   18787 C CG  . ARG F 1 391 ? -5.170  45.067  57.873  1.00 21.91  ? 391 ARG F CG  1 
ATOM   18788 C CD  . ARG F 1 391 ? -4.154  45.638  58.831  1.00 22.10  ? 391 ARG F CD  1 
ATOM   18789 N NE  . ARG F 1 391 ? -4.586  45.454  60.213  1.00 25.83  ? 391 ARG F NE  1 
ATOM   18790 C CZ  . ARG F 1 391 ? -3.845  45.722  61.278  1.00 23.56  ? 391 ARG F CZ  1 
ATOM   18791 N NH1 . ARG F 1 391 ? -2.627  46.229  61.166  1.00 26.95  ? 391 ARG F NH1 1 
ATOM   18792 N NH2 . ARG F 1 391 ? -4.337  45.480  62.482  1.00 22.12  ? 391 ARG F NH2 1 
ATOM   18793 N N   . TYR F 1 392 ? -7.789  43.748  56.372  1.00 24.81  ? 392 TYR F N   1 
ATOM   18794 C CA  . TYR F 1 392 ? -9.223  43.790  56.621  1.00 28.70  ? 392 TYR F CA  1 
ATOM   18795 C C   . TYR F 1 392 ? -9.605  45.116  57.253  1.00 27.35  ? 392 TYR F C   1 
ATOM   18796 O O   . TYR F 1 392 ? -8.968  45.571  58.203  1.00 26.98  ? 392 TYR F O   1 
ATOM   18797 C CB  . TYR F 1 392 ? -9.692  42.652  57.537  1.00 25.88  ? 392 TYR F CB  1 
ATOM   18798 C CG  . TYR F 1 392 ? -11.192 42.771  57.812  1.00 27.69  ? 392 TYR F CG  1 
ATOM   18799 C CD1 . TYR F 1 392 ? -12.114 42.280  56.904  1.00 27.11  ? 392 TYR F CD1 1 
ATOM   18800 C CD2 . TYR F 1 392 ? -11.682 43.423  58.948  1.00 27.31  ? 392 TYR F CD2 1 
ATOM   18801 C CE1 . TYR F 1 392 ? -13.469 42.412  57.116  1.00 29.78  ? 392 TYR F CE1 1 
ATOM   18802 C CE2 . TYR F 1 392 ? -13.052 43.546  59.175  1.00 23.25  ? 392 TYR F CE2 1 
ATOM   18803 C CZ  . TYR F 1 392 ? -13.939 43.036  58.245  1.00 28.72  ? 392 TYR F CZ  1 
ATOM   18804 O OH  . TYR F 1 392 ? -15.309 43.126  58.416  1.00 33.30  ? 392 TYR F OH  1 
ATOM   18805 N N   . ASP F 1 393 ? -10.678 45.701  56.734  1.00 33.26  ? 393 ASP F N   1 
ATOM   18806 C CA  . ASP F 1 393 ? -11.092 47.067  57.025  1.00 32.17  ? 393 ASP F CA  1 
ATOM   18807 C C   . ASP F 1 393 ? -12.555 46.975  57.446  1.00 30.11  ? 393 ASP F C   1 
ATOM   18808 O O   . ASP F 1 393 ? -13.430 46.803  56.592  1.00 29.11  ? 393 ASP F O   1 
ATOM   18809 C CB  . ASP F 1 393 ? -10.887 47.957  55.793  1.00 30.89  ? 393 ASP F CB  1 
ATOM   18810 C CG  . ASP F 1 393 ? -11.557 49.332  55.924  1.00 38.79  ? 393 ASP F CG  1 
ATOM   18811 O OD1 . ASP F 1 393 ? -11.738 49.838  57.053  1.00 40.29  ? 393 ASP F OD1 1 
ATOM   18812 O OD2 . ASP F 1 393 ? -11.886 49.918  54.879  1.00 40.20  ? 393 ASP F OD2 1 
ATOM   18813 N N   . LYS F 1 394 ? -12.814 47.071  58.757  1.00 26.58  ? 394 LYS F N   1 
ATOM   18814 C CA  . LYS F 1 394 ? -14.169 46.874  59.275  1.00 31.71  ? 394 LYS F CA  1 
ATOM   18815 C C   . LYS F 1 394 ? -15.177 47.877  58.713  1.00 34.26  ? 394 LYS F C   1 
ATOM   18816 O O   . LYS F 1 394 ? -16.379 47.668  58.883  1.00 39.78  ? 394 LYS F O   1 
ATOM   18817 C CB  . LYS F 1 394 ? -14.173 46.906  60.826  1.00 30.42  ? 394 LYS F CB  1 
ATOM   18818 C CG  . LYS F 1 394 ? -14.086 48.301  61.487  1.00 38.98  ? 394 LYS F CG  1 
ATOM   18819 C CD  . LYS F 1 394 ? -15.454 48.998  61.643  1.00 43.62  ? 394 LYS F CD  1 
ATOM   18820 C CE  . LYS F 1 394 ? -15.400 50.225  62.561  1.00 52.73  ? 394 LYS F CE  1 
ATOM   18821 N NZ  . LYS F 1 394 ? -16.763 50.845  62.746  1.00 51.63  ? 394 LYS F NZ  1 
ATOM   18822 N N   . ASP F 1 395 ? -14.730 48.952  58.058  1.00 36.35  ? 395 ASP F N   1 
ATOM   18823 C CA  . ASP F 1 395 ? -15.672 49.876  57.436  1.00 35.77  ? 395 ASP F CA  1 
ATOM   18824 C C   . ASP F 1 395 ? -16.197 49.339  56.112  1.00 38.70  ? 395 ASP F C   1 
ATOM   18825 O O   . ASP F 1 395 ? -17.371 49.538  55.782  1.00 42.27  ? 395 ASP F O   1 
ATOM   18826 C CB  . ASP F 1 395 ? -15.019 51.240  57.195  1.00 41.55  ? 395 ASP F CB  1 
ATOM   18827 C CG  . ASP F 1 395 ? -14.797 52.038  58.475  1.00 44.51  ? 395 ASP F CG  1 
ATOM   18828 O OD1 . ASP F 1 395 ? -15.722 52.152  59.307  1.00 42.85  ? 395 ASP F OD1 1 
ATOM   18829 O OD2 . ASP F 1 395 ? -13.680 52.572  58.636  1.00 47.55  ? 395 ASP F OD2 1 
ATOM   18830 N N   . SER F 1 396 ? -15.345 48.696  55.317  1.00 33.77  ? 396 SER F N   1 
ATOM   18831 C CA  . SER F 1 396 ? -15.790 48.211  54.017  1.00 35.01  ? 396 SER F CA  1 
ATOM   18832 C C   . SER F 1 396 ? -16.247 46.763  54.045  1.00 32.41  ? 396 SER F C   1 
ATOM   18833 O O   . SER F 1 396 ? -16.955 46.340  53.129  1.00 33.36  ? 396 SER F O   1 
ATOM   18834 C CB  . SER F 1 396 ? -14.680 48.359  52.968  1.00 39.19  ? 396 SER F CB  1 
ATOM   18835 O OG  . SER F 1 396 ? -13.437 47.842  53.425  1.00 36.23  ? 396 SER F OG  1 
ATOM   18836 N N   . GLY F 1 397 ? -15.868 45.999  55.064  1.00 34.83  ? 397 GLY F N   1 
ATOM   18837 C CA  . GLY F 1 397 ? -16.088 44.566  55.036  1.00 31.21  ? 397 GLY F CA  1 
ATOM   18838 C C   . GLY F 1 397 ? -15.182 43.828  54.083  1.00 35.68  ? 397 GLY F C   1 
ATOM   18839 O O   . GLY F 1 397 ? -15.477 42.694  53.709  1.00 34.89  ? 397 GLY F O   1 
ATOM   18840 N N   . GLU F 1 398 ? -14.079 44.438  53.669  1.00 34.08  ? 398 GLU F N   1 
ATOM   18841 C CA  . GLU F 1 398 ? -13.232 43.848  52.649  1.00 31.65  ? 398 GLU F CA  1 
ATOM   18842 C C   . GLU F 1 398 ? -11.785 43.863  53.108  1.00 31.87  ? 398 GLU F C   1 
ATOM   18843 O O   . GLU F 1 398 ? -11.362 44.749  53.859  1.00 31.41  ? 398 GLU F O   1 
ATOM   18844 C CB  . GLU F 1 398 ? -13.391 44.589  51.329  1.00 38.48  ? 398 GLU F CB  1 
ATOM   18845 C CG  . GLU F 1 398 ? -14.669 44.194  50.613  1.00 43.02  ? 398 GLU F CG  1 
ATOM   18846 C CD  . GLU F 1 398 ? -15.040 45.124  49.485  1.00 46.04  ? 398 GLU F CD  1 
ATOM   18847 O OE1 . GLU F 1 398 ? -14.768 46.343  49.604  1.00 55.47  ? 398 GLU F OE1 1 
ATOM   18848 O OE2 . GLU F 1 398 ? -15.622 44.632  48.491  1.00 40.29  ? 398 GLU F OE2 1 
ATOM   18849 N N   . GLY F 1 399 ? -11.031 42.875  52.658  1.00 26.38  ? 399 GLY F N   1 
ATOM   18850 C CA  . GLY F 1 399 ? -9.649  42.733  53.071  1.00 27.64  ? 399 GLY F CA  1 
ATOM   18851 C C   . GLY F 1 399 ? -9.412  41.420  53.787  1.00 21.84  ? 399 GLY F C   1 
ATOM   18852 O O   . GLY F 1 399 ? -10.248 40.519  53.782  1.00 21.21  ? 399 GLY F O   1 
ATOM   18853 N N   . ALA F 1 400 ? -8.246  41.317  54.425  1.00 27.43  ? 400 ALA F N   1 
ATOM   18854 C CA  . ALA F 1 400 ? -7.731  40.025  54.852  1.00 24.23  ? 400 ALA F CA  1 
ATOM   18855 C C   . ALA F 1 400 ? -7.368  40.027  56.322  1.00 24.47  ? 400 ALA F C   1 
ATOM   18856 O O   . ALA F 1 400 ? -6.952  41.045  56.885  1.00 24.71  ? 400 ALA F O   1 
ATOM   18857 C CB  . ALA F 1 400 ? -6.508  39.614  54.041  1.00 23.43  ? 400 ALA F CB  1 
ATOM   18858 N N   . VAL F 1 401 ? -7.534  38.857  56.933  1.00 21.89  ? 401 VAL F N   1 
ATOM   18859 C CA  . VAL F 1 401 ? -7.202  38.618  58.328  1.00 23.10  ? 401 VAL F CA  1 
ATOM   18860 C C   . VAL F 1 401 ? -6.221  37.456  58.370  1.00 27.00  ? 401 VAL F C   1 
ATOM   18861 O O   . VAL F 1 401 ? -6.142  36.658  57.435  1.00 23.13  ? 401 VAL F O   1 
ATOM   18862 C CB  . VAL F 1 401 ? -8.456  38.306  59.162  1.00 25.43  ? 401 VAL F CB  1 
ATOM   18863 C CG1 . VAL F 1 401 ? -9.557  39.275  58.790  1.00 24.91  ? 401 VAL F CG1 1 
ATOM   18864 C CG2 . VAL F 1 401 ? -8.927  36.876  58.909  1.00 25.91  ? 401 VAL F CG2 1 
ATOM   18865 N N   . VAL F 1 402 ? -5.482  37.358  59.476  1.00 25.18  ? 402 VAL F N   1 
ATOM   18866 C CA  . VAL F 1 402 ? -4.434  36.359  59.643  1.00 24.99  ? 402 VAL F CA  1 
ATOM   18867 C C   . VAL F 1 402 ? -4.910  35.287  60.615  1.00 26.74  ? 402 VAL F C   1 
ATOM   18868 O O   . VAL F 1 402 ? -5.171  35.574  61.787  1.00 27.28  ? 402 VAL F O   1 
ATOM   18869 C CB  . VAL F 1 402 ? -3.124  36.994  60.129  1.00 28.81  ? 402 VAL F CB  1 
ATOM   18870 C CG1 . VAL F 1 402 ? -2.002  35.965  60.089  1.00 29.83  ? 402 VAL F CG1 1 
ATOM   18871 C CG2 . VAL F 1 402 ? -2.768  38.177  59.246  1.00 27.03  ? 402 VAL F CG2 1 
ATOM   18872 N N   . LEU F 1 403 ? -4.995  34.044  60.134  1.00 27.32  ? 403 LEU F N   1 
ATOM   18873 C CA  . LEU F 1 403 ? -5.340  32.901  60.970  1.00 23.57  ? 403 LEU F CA  1 
ATOM   18874 C C   . LEU F 1 403 ? -4.116  32.153  61.462  1.00 33.43  ? 403 LEU F C   1 
ATOM   18875 O O   . LEU F 1 403 ? -4.208  31.418  62.456  1.00 30.12  ? 403 LEU F O   1 
ATOM   18876 C CB  . LEU F 1 403 ? -6.216  31.914  60.200  1.00 22.74  ? 403 LEU F CB  1 
ATOM   18877 C CG  . LEU F 1 403 ? -7.608  32.336  59.707  1.00 28.36  ? 403 LEU F CG  1 
ATOM   18878 C CD1 . LEU F 1 403 ? -8.566  31.165  59.765  1.00 21.30  ? 403 LEU F CD1 1 
ATOM   18879 C CD2 . LEU F 1 403 ? -8.160  33.547  60.447  1.00 19.83  ? 403 LEU F CD2 1 
ATOM   18880 N N   . GLY F 1 404 ? -2.985  32.296  60.776  1.00 24.39  ? 404 GLY F N   1 
ATOM   18881 C CA  . GLY F 1 404 ? -1.781  31.639  61.231  1.00 28.73  ? 404 GLY F CA  1 
ATOM   18882 C C   . GLY F 1 404 ? -0.540  32.253  60.633  1.00 29.39  ? 404 GLY F C   1 
ATOM   18883 O O   . GLY F 1 404 ? -0.515  32.593  59.447  1.00 30.29  ? 404 GLY F O   1 
ATOM   18884 N N   . CYS F 1 405 ? 0.506   32.394  61.432  1.00 27.66  ? 405 CYS F N   1 
ATOM   18885 C CA  . CYS F 1 405 ? 1.721   32.995  60.904  1.00 33.95  ? 405 CYS F CA  1 
ATOM   18886 C C   . CYS F 1 405 ? 2.647   31.976  60.291  1.00 32.60  ? 405 CYS F C   1 
ATOM   18887 O O   . CYS F 1 405 ? 3.406   32.305  59.374  1.00 26.18  ? 405 CYS F O   1 
ATOM   18888 C CB  . CYS F 1 405 ? 2.465   33.746  62.004  1.00 33.81  ? 405 CYS F CB  1 
ATOM   18889 S SG  . CYS F 1 405 ? 1.593   35.203  62.573  1.00 35.23  ? 405 CYS F SG  1 
ATOM   18890 N N   . ASN F 1 406 ? 2.564   30.744  60.776  1.00 38.50  ? 406 ASN F N   1 
ATOM   18891 C CA  . ASN F 1 406 ? 3.566   29.721  60.545  1.00 37.46  ? 406 ASN F CA  1 
ATOM   18892 C C   . ASN F 1 406 ? 2.880   28.373  60.680  1.00 37.37  ? 406 ASN F C   1 
ATOM   18893 O O   . ASN F 1 406 ? 3.152   27.615  61.616  1.00 41.01  ? 406 ASN F O   1 
ATOM   18894 C CB  . ASN F 1 406 ? 4.713   29.869  61.544  1.00 33.66  ? 406 ASN F CB  1 
ATOM   18895 C CG  . ASN F 1 406 ? 5.798   28.868  61.311  1.00 33.32  ? 406 ASN F CG  1 
ATOM   18896 O OD1 . ASN F 1 406 ? 6.004   28.430  60.189  1.00 28.41  ? 406 ASN F OD1 1 
ATOM   18897 N ND2 . ASN F 1 406 ? 6.498   28.490  62.372  1.00 34.85  ? 406 ASN F ND2 1 
ATOM   18898 N N   . SER F 1 407 ? 1.952   28.095  59.781  1.00 34.18  ? 407 SER F N   1 
ATOM   18899 C CA  . SER F 1 407 ? 1.064   26.949  59.892  1.00 36.15  ? 407 SER F CA  1 
ATOM   18900 C C   . SER F 1 407 ? 1.517   25.831  58.961  1.00 32.88  ? 407 SER F C   1 
ATOM   18901 O O   . SER F 1 407 ? 2.096   26.076  57.901  1.00 30.46  ? 407 SER F O   1 
ATOM   18902 C CB  . SER F 1 407 ? -0.375  27.354  59.552  1.00 31.45  ? 407 SER F CB  1 
ATOM   18903 O OG  . SER F 1 407 ? -1.249  26.241  59.590  1.00 37.07  ? 407 SER F OG  1 
ATOM   18904 N N   . ASP F 1 408 ? 1.236   24.595  59.352  1.00 36.27  ? 408 ASP F N   1 
ATOM   18905 C CA  . ASP F 1 408 ? 1.529   23.478  58.469  1.00 39.81  ? 408 ASP F CA  1 
ATOM   18906 C C   . ASP F 1 408 ? 0.299   23.010  57.687  1.00 37.42  ? 408 ASP F C   1 
ATOM   18907 O O   . ASP F 1 408 ? 0.361   21.975  57.019  1.00 42.95  ? 408 ASP F O   1 
ATOM   18908 C CB  . ASP F 1 408 ? 2.172   22.338  59.261  1.00 40.24  ? 408 ASP F CB  1 
ATOM   18909 C CG  . ASP F 1 408 ? 1.542   22.150  60.604  1.00 45.30  ? 408 ASP F CG  1 
ATOM   18910 O OD1 . ASP F 1 408 ? 0.298   22.103  60.634  1.00 46.24  ? 408 ASP F OD1 1 
ATOM   18911 O OD2 . ASP F 1 408 ? 2.276   22.080  61.620  1.00 41.83  ? 408 ASP F OD2 1 
ATOM   18912 N N   . LEU F 1 409 ? -0.799  23.766  57.717  1.00 34.51  ? 409 LEU F N   1 
ATOM   18913 C CA  . LEU F 1 409 ? -1.862  23.551  56.742  1.00 33.51  ? 409 LEU F CA  1 
ATOM   18914 C C   . LEU F 1 409 ? -1.289  23.797  55.359  1.00 39.38  ? 409 LEU F C   1 
ATOM   18915 O O   . LEU F 1 409 ? -0.917  24.936  55.056  1.00 36.64  ? 409 LEU F O   1 
ATOM   18916 C CB  . LEU F 1 409 ? -3.030  24.506  56.979  1.00 33.94  ? 409 LEU F CB  1 
ATOM   18917 C CG  . LEU F 1 409 ? -3.929  24.472  58.206  1.00 33.33  ? 409 LEU F CG  1 
ATOM   18918 C CD1 . LEU F 1 409 ? -5.153  25.388  57.934  1.00 31.76  ? 409 LEU F CD1 1 
ATOM   18919 C CD2 . LEU F 1 409 ? -4.369  23.067  58.544  1.00 37.09  ? 409 LEU F CD2 1 
ATOM   18920 N N   . GLY F 1 410 ? -1.236  22.742  54.521  1.00 38.10  ? 410 GLY F N   1 
ATOM   18921 C CA  . GLY F 1 410 ? -0.375  22.714  53.347  1.00 45.33  ? 410 GLY F CA  1 
ATOM   18922 C C   . GLY F 1 410 ? 0.608   23.861  53.407  1.00 37.61  ? 410 GLY F C   1 
ATOM   18923 O O   . GLY F 1 410 ? 0.328   24.948  52.906  1.00 42.67  ? 410 GLY F O   1 
ATOM   18924 N N   . PRO F 1 411 ? 1.765   23.646  54.031  1.00 38.66  ? 411 PRO F N   1 
ATOM   18925 C CA  . PRO F 1 411 ? 2.285   24.617  55.011  1.00 35.61  ? 411 PRO F CA  1 
ATOM   18926 C C   . PRO F 1 411 ? 2.439   26.038  54.485  1.00 34.61  ? 411 PRO F C   1 
ATOM   18927 O O   . PRO F 1 411 ? 2.523   26.297  53.281  1.00 36.25  ? 411 PRO F O   1 
ATOM   18928 C CB  . PRO F 1 411 ? 3.649   24.032  55.383  1.00 37.59  ? 411 PRO F CB  1 
ATOM   18929 C CG  . PRO F 1 411 ? 4.081   23.359  54.104  1.00 39.34  ? 411 PRO F CG  1 
ATOM   18930 C CD  . PRO F 1 411 ? 2.835   22.776  53.503  1.00 38.70  ? 411 PRO F CD  1 
ATOM   18931 N N   . GLY F 1 412 ? 2.511   26.962  55.424  1.00 32.81  ? 412 GLY F N   1 
ATOM   18932 C CA  . GLY F 1 412 ? 2.603   28.377  55.119  1.00 32.66  ? 412 GLY F CA  1 
ATOM   18933 C C   . GLY F 1 412 ? 1.889   29.170  56.194  1.00 35.23  ? 412 GLY F C   1 
ATOM   18934 O O   . GLY F 1 412 ? 1.421   28.627  57.192  1.00 32.33  ? 412 GLY F O   1 
ATOM   18935 N N   . ALA F 1 413 ? 1.832   30.481  55.981  1.00 28.29  ? 413 ALA F N   1 
ATOM   18936 C CA  . ALA F 1 413 ? 0.995   31.339  56.802  1.00 29.84  ? 413 ALA F CA  1 
ATOM   18937 C C   . ALA F 1 413 ? -0.402  31.347  56.194  1.00 28.54  ? 413 ALA F C   1 
ATOM   18938 O O   . ALA F 1 413 ? -0.550  31.434  54.971  1.00 29.15  ? 413 ALA F O   1 
ATOM   18939 C CB  . ALA F 1 413 ? 1.553   32.759  56.879  1.00 29.61  ? 413 ALA F CB  1 
ATOM   18940 N N   . GLU F 1 414 ? -1.416  31.233  57.037  1.00 28.57  ? 414 GLU F N   1 
ATOM   18941 C CA  . GLU F 1 414 ? -2.797  31.095  56.580  1.00 32.36  ? 414 GLU F CA  1 
ATOM   18942 C C   . GLU F 1 414 ? -3.476  32.453  56.676  1.00 25.78  ? 414 GLU F C   1 
ATOM   18943 O O   . GLU F 1 414 ? -3.496  33.063  57.744  1.00 24.33  ? 414 GLU F O   1 
ATOM   18944 C CB  . GLU F 1 414 ? -3.539  30.046  57.412  1.00 25.37  ? 414 GLU F CB  1 
ATOM   18945 C CG  . GLU F 1 414 ? -4.997  29.820  57.024  1.00 28.54  ? 414 GLU F CG  1 
ATOM   18946 C CD  . GLU F 1 414 ? -5.699  28.830  57.969  1.00 30.05  ? 414 GLU F CD  1 
ATOM   18947 O OE1 . GLU F 1 414 ? -5.229  28.641  59.116  1.00 28.46  ? 414 GLU F OE1 1 
ATOM   18948 O OE2 . GLU F 1 414 ? -6.713  28.230  57.563  1.00 27.08  ? 414 GLU F OE2 1 
ATOM   18949 N N   . LEU F 1 415 ? -4.008  32.931  55.562  1.00 30.47  ? 415 LEU F N   1 
ATOM   18950 C CA  . LEU F 1 415 ? -4.826  34.135  55.547  1.00 26.41  ? 415 LEU F CA  1 
ATOM   18951 C C   . LEU F 1 415 ? -6.218  33.777  55.054  1.00 30.66  ? 415 LEU F C   1 
ATOM   18952 O O   . LEU F 1 415 ? -6.443  32.709  54.475  1.00 32.83  ? 415 LEU F O   1 
ATOM   18953 C CB  . LEU F 1 415 ? -4.226  35.221  54.633  1.00 26.11  ? 415 LEU F CB  1 
ATOM   18954 C CG  . LEU F 1 415 ? -2.760  35.606  54.830  1.00 29.87  ? 415 LEU F CG  1 
ATOM   18955 C CD1 . LEU F 1 415 ? -2.241  36.267  53.571  1.00 32.89  ? 415 LEU F CD1 1 
ATOM   18956 C CD2 . LEU F 1 415 ? -2.584  36.533  56.010  1.00 22.96  ? 415 LEU F CD2 1 
ATOM   18957 N N   . LEU F 1 416 ? -7.137  34.721  55.257  1.00 27.03  ? 416 LEU F N   1 
ATOM   18958 C CA  . LEU F 1 416 ? -8.520  34.643  54.813  1.00 24.83  ? 416 LEU F CA  1 
ATOM   18959 C C   . LEU F 1 416 ? -8.931  36.007  54.266  1.00 21.00  ? 416 LEU F C   1 
ATOM   18960 O O   . LEU F 1 416 ? -8.756  37.027  54.937  1.00 21.70  ? 416 LEU F O   1 
ATOM   18961 C CB  . LEU F 1 416 ? -9.417  34.244  55.976  1.00 20.47  ? 416 LEU F CB  1 
ATOM   18962 C CG  . LEU F 1 416 ? -10.919 34.218  55.701  1.00 24.40  ? 416 LEU F CG  1 
ATOM   18963 C CD1 . LEU F 1 416 ? -11.251 33.283  54.520  1.00 21.27  ? 416 LEU F CD1 1 
ATOM   18964 C CD2 . LEU F 1 416 ? -11.642 33.799  56.980  1.00 20.62  ? 416 LEU F CD2 1 
ATOM   18965 N N   . VAL F 1 417 ? -9.481  36.038  53.067  1.00 20.67  ? 417 VAL F N   1 
ATOM   18966 C CA  . VAL F 1 417 ? -9.743  37.297  52.386  1.00 19.68  ? 417 VAL F CA  1 
ATOM   18967 C C   . VAL F 1 417 ? -11.220 37.410  52.046  1.00 23.58  ? 417 VAL F C   1 
ATOM   18968 O O   . VAL F 1 417 ? -11.830 36.464  51.540  1.00 26.90  ? 417 VAL F O   1 
ATOM   18969 C CB  . VAL F 1 417 ? -8.884  37.433  51.114  1.00 24.69  ? 417 VAL F CB  1 
ATOM   18970 C CG1 . VAL F 1 417 ? -8.956  38.885  50.568  1.00 22.17  ? 417 VAL F CG1 1 
ATOM   18971 C CG2 . VAL F 1 417 ? -7.430  36.991  51.412  1.00 27.14  ? 417 VAL F CG2 1 
ATOM   18972 N N   . PHE F 1 418 ? -11.783 38.586  52.285  1.00 26.29  ? 418 PHE F N   1 
ATOM   18973 C CA  . PHE F 1 418 ? -13.201 38.834  52.081  1.00 26.52  ? 418 PHE F CA  1 
ATOM   18974 C C   . PHE F 1 418 ? -13.399 39.915  51.037  1.00 27.30  ? 418 PHE F C   1 
ATOM   18975 O O   . PHE F 1 418 ? -12.662 40.906  51.023  1.00 29.83  ? 418 PHE F O   1 
ATOM   18976 C CB  . PHE F 1 418 ? -13.866 39.309  53.359  1.00 29.54  ? 418 PHE F CB  1 
ATOM   18977 C CG  . PHE F 1 418 ? -13.785 38.354  54.503  1.00 23.54  ? 418 PHE F CG  1 
ATOM   18978 C CD1 . PHE F 1 418 ? -14.775 37.402  54.694  1.00 25.52  ? 418 PHE F CD1 1 
ATOM   18979 C CD2 . PHE F 1 418 ? -12.784 38.471  55.447  1.00 23.20  ? 418 PHE F CD2 1 
ATOM   18980 C CE1 . PHE F 1 418 ? -14.736 36.540  55.792  1.00 26.92  ? 418 PHE F CE1 1 
ATOM   18981 C CE2 . PHE F 1 418 ? -12.736 37.621  56.549  1.00 19.87  ? 418 PHE F CE2 1 
ATOM   18982 C CZ  . PHE F 1 418 ? -13.704 36.653  56.716  1.00 23.18  ? 418 PHE F CZ  1 
ATOM   18983 N N   . SER F 1 419 ? -14.422 39.752  50.197  1.00 28.97  ? 419 SER F N   1 
ATOM   18984 C CA  . SER F 1 419 ? -14.864 40.830  49.313  1.00 32.15  ? 419 SER F CA  1 
ATOM   18985 C C   . SER F 1 419 ? -16.343 40.669  48.985  1.00 34.21  ? 419 SER F C   1 
ATOM   18986 O O   . SER F 1 419 ? -16.865 39.548  48.946  1.00 32.85  ? 419 SER F O   1 
ATOM   18987 C CB  . SER F 1 419 ? -14.062 40.873  48.007  1.00 33.09  ? 419 SER F CB  1 
ATOM   18988 O OG  . SER F 1 419 ? -14.427 42.007  47.217  1.00 37.75  ? 419 SER F OG  1 
ATOM   18989 N N   . LYS F 1 420 ? -17.014 41.803  48.738  1.00 32.50  ? 420 LYS F N   1 
ATOM   18990 C CA  . LYS F 1 420 ? -18.351 41.760  48.160  1.00 31.71  ? 420 LYS F CA  1 
ATOM   18991 C C   . LYS F 1 420 ? -18.322 41.436  46.681  1.00 31.09  ? 420 LYS F C   1 
ATOM   18992 O O   . LYS F 1 420 ? -19.382 41.239  46.080  1.00 32.98  ? 420 LYS F O   1 
ATOM   18993 C CB  . LYS F 1 420 ? -19.093 43.090  48.342  1.00 29.91  ? 420 LYS F CB  1 
ATOM   18994 C CG  . LYS F 1 420 ? -19.147 43.619  49.761  1.00 32.18  ? 420 LYS F CG  1 
ATOM   18995 C CD  . LYS F 1 420 ? -19.632 45.067  49.792  1.00 36.80  ? 420 LYS F CD  1 
ATOM   18996 C CE  . LYS F 1 420 ? -18.506 46.060  50.116  1.00 43.29  ? 420 LYS F CE  1 
ATOM   18997 N NZ  . LYS F 1 420 ? -17.692 46.480  48.919  1.00 41.84  ? 420 LYS F NZ  1 
ATOM   18998 N N   . ASP F 1 421 ? -17.149 41.372  46.076  1.00 28.98  ? 421 ASP F N   1 
ATOM   18999 C CA  . ASP F 1 421 ? -17.052 41.175  44.639  1.00 35.14  ? 421 ASP F CA  1 
ATOM   19000 C C   . ASP F 1 421 ? -16.040 40.084  44.328  1.00 33.96  ? 421 ASP F C   1 
ATOM   19001 O O   . ASP F 1 421 ? -14.899 40.159  44.787  1.00 33.16  ? 421 ASP F O   1 
ATOM   19002 C CB  . ASP F 1 421 ? -16.651 42.482  43.969  1.00 36.29  ? 421 ASP F CB  1 
ATOM   19003 C CG  . ASP F 1 421 ? -16.663 42.377  42.487  1.00 41.21  ? 421 ASP F CG  1 
ATOM   19004 O OD1 . ASP F 1 421 ? -17.778 42.352  41.918  1.00 48.82  ? 421 ASP F OD1 1 
ATOM   19005 O OD2 . ASP F 1 421 ? -15.558 42.277  41.906  1.00 40.44  ? 421 ASP F OD2 1 
ATOM   19006 N N   . TRP F 1 422 ? -16.443 39.084  43.535  1.00 32.74  ? 422 TRP F N   1 
ATOM   19007 C CA  . TRP F 1 422 ? -15.579 37.917  43.353  1.00 36.52  ? 422 TRP F CA  1 
ATOM   19008 C C   . TRP F 1 422 ? -14.291 38.274  42.611  1.00 41.04  ? 422 TRP F C   1 
ATOM   19009 O O   . TRP F 1 422 ? -13.192 37.936  43.072  1.00 35.90  ? 422 TRP F O   1 
ATOM   19010 C CB  . TRP F 1 422 ? -16.310 36.790  42.622  1.00 37.03  ? 422 TRP F CB  1 
ATOM   19011 C CG  . TRP F 1 422 ? -15.414 35.585  42.379  1.00 42.77  ? 422 TRP F CG  1 
ATOM   19012 C CD1 . TRP F 1 422 ? -14.976 35.113  41.168  1.00 46.42  ? 422 TRP F CD1 1 
ATOM   19013 C CD2 . TRP F 1 422 ? -14.845 34.717  43.373  1.00 38.44  ? 422 TRP F CD2 1 
ATOM   19014 N NE1 . TRP F 1 422 ? -14.182 34.000  41.351  1.00 51.81  ? 422 TRP F NE1 1 
ATOM   19015 C CE2 . TRP F 1 422 ? -14.081 33.741  42.693  1.00 46.89  ? 422 TRP F CE2 1 
ATOM   19016 C CE3 . TRP F 1 422 ? -14.901 34.674  44.770  1.00 42.65  ? 422 TRP F CE3 1 
ATOM   19017 C CZ2 . TRP F 1 422 ? -13.380 32.733  43.365  1.00 51.15  ? 422 TRP F CZ2 1 
ATOM   19018 C CZ3 . TRP F 1 422 ? -14.199 33.659  45.445  1.00 43.56  ? 422 TRP F CZ3 1 
ATOM   19019 C CH2 . TRP F 1 422 ? -13.450 32.711  44.740  1.00 49.20  ? 422 TRP F CH2 1 
ATOM   19020 N N   . ASP F 1 423 ? -14.404 38.931  41.446  1.00 36.22  ? 423 ASP F N   1 
ATOM   19021 C CA  . ASP F 1 423 ? -13.204 39.317  40.703  1.00 38.43  ? 423 ASP F CA  1 
ATOM   19022 C C   . ASP F 1 423 ? -12.289 40.178  41.561  1.00 35.03  ? 423 ASP F C   1 
ATOM   19023 O O   . ASP F 1 423 ? -11.062 40.085  41.461  1.00 33.22  ? 423 ASP F O   1 
ATOM   19024 C CB  . ASP F 1 423 ? -13.577 40.065  39.418  1.00 38.64  ? 423 ASP F CB  1 
ATOM   19025 C CG  . ASP F 1 423 ? -14.303 39.182  38.407  1.00 40.77  ? 423 ASP F CG  1 
ATOM   19026 O OD1 . ASP F 1 423 ? -14.274 37.943  38.556  1.00 45.68  ? 423 ASP F OD1 1 
ATOM   19027 O OD2 . ASP F 1 423 ? -14.919 39.732  37.468  1.00 43.15  ? 423 ASP F OD2 1 
ATOM   19028 N N   . ARG F 1 424 ? -12.871 41.019  42.418  1.00 39.01  ? 424 ARG F N   1 
ATOM   19029 C CA  . ARG F 1 424 ? -12.070 41.823  43.338  1.00 35.60  ? 424 ARG F CA  1 
ATOM   19030 C C   . ARG F 1 424 ? -11.350 40.940  44.355  1.00 32.87  ? 424 ARG F C   1 
ATOM   19031 O O   . ARG F 1 424 ? -10.216 41.233  44.752  1.00 33.14  ? 424 ARG F O   1 
ATOM   19032 C CB  . ARG F 1 424 ? -12.971 42.843  44.033  1.00 32.75  ? 424 ARG F CB  1 
ATOM   19033 C CG  . ARG F 1 424 ? -12.286 44.058  44.604  1.00 39.66  ? 424 ARG F CG  1 
ATOM   19034 C CD  . ARG F 1 424 ? -13.348 45.022  45.146  1.00 49.65  ? 424 ARG F CD  1 
ATOM   19035 N NE  . ARG F 1 424 ? -12.981 45.577  46.444  1.00 59.61  ? 424 ARG F NE  1 
ATOM   19036 C CZ  . ARG F 1 424 ? -13.060 46.864  46.760  1.00 63.65  ? 424 ARG F CZ  1 
ATOM   19037 N NH1 . ARG F 1 424 ? -13.514 47.762  45.897  1.00 65.32  ? 424 ARG F NH1 1 
ATOM   19038 N NH2 . ARG F 1 424 ? -12.679 47.261  47.975  1.00 60.46  ? 424 ARG F NH2 1 
ATOM   19039 N N   . LEU F 1 425 ? -11.992 39.851  44.793  1.00 34.13  ? 425 LEU F N   1 
ATOM   19040 C CA  . LEU F 1 425 ? -11.310 38.923  45.686  1.00 32.11  ? 425 LEU F CA  1 
ATOM   19041 C C   . LEU F 1 425 ? -10.029 38.401  45.041  1.00 31.44  ? 425 LEU F C   1 
ATOM   19042 O O   . LEU F 1 425 ? -8.967  38.384  45.673  1.00 33.45  ? 425 LEU F O   1 
ATOM   19043 C CB  . LEU F 1 425 ? -12.241 37.767  46.074  1.00 35.52  ? 425 LEU F CB  1 
ATOM   19044 C CG  . LEU F 1 425 ? -12.081 37.179  47.491  1.00 35.21  ? 425 LEU F CG  1 
ATOM   19045 C CD1 . LEU F 1 425 ? -12.929 35.912  47.725  1.00 31.83  ? 425 LEU F CD1 1 
ATOM   19046 C CD2 . LEU F 1 425 ? -10.637 36.875  47.786  1.00 31.20  ? 425 LEU F CD2 1 
ATOM   19047 N N   . THR F 1 426 ? -10.110 37.963  43.784  1.00 26.27  ? 426 THR F N   1 
ATOM   19048 C CA  . THR F 1 426 ? -8.929  37.426  43.117  1.00 35.93  ? 426 THR F CA  1 
ATOM   19049 C C   . THR F 1 426 ? -7.850  38.494  42.973  1.00 37.79  ? 426 THR F C   1 
ATOM   19050 O O   . THR F 1 426 ? -6.653  38.212  43.142  1.00 31.86  ? 426 THR F O   1 
ATOM   19051 C CB  . THR F 1 426 ? -9.308  36.853  41.750  1.00 38.14  ? 426 THR F CB  1 
ATOM   19052 O OG1 . THR F 1 426 ? -10.395 35.937  41.910  1.00 42.43  ? 426 THR F OG1 1 
ATOM   19053 C CG2 . THR F 1 426 ? -8.126  36.103  41.131  1.00 40.86  ? 426 THR F CG2 1 
ATOM   19054 N N   . ALA F 1 427 ? -8.258  39.730  42.680  1.00 29.31  ? 427 ALA F N   1 
ATOM   19055 C CA  . ALA F 1 427 ? -7.301  40.826  42.626  1.00 31.38  ? 427 ALA F CA  1 
ATOM   19056 C C   . ALA F 1 427 ? -6.569  40.998  43.958  1.00 35.84  ? 427 ALA F C   1 
ATOM   19057 O O   . ALA F 1 427 ? -5.343  41.182  43.980  1.00 30.31  ? 427 ALA F O   1 
ATOM   19058 C CB  . ALA F 1 427 ? -8.007  42.122  42.224  1.00 27.70  ? 427 ALA F CB  1 
ATOM   19059 N N   . MET F 1 428 ? -7.302  40.963  45.086  1.00 32.59  ? 428 MET F N   1 
ATOM   19060 C CA  . MET F 1 428 ? -6.624  41.100  46.375  1.00 30.83  ? 428 MET F CA  1 
ATOM   19061 C C   . MET F 1 428 ? -5.659  39.951  46.602  1.00 31.12  ? 428 MET F C   1 
ATOM   19062 O O   . MET F 1 428 ? -4.535  40.161  47.073  1.00 35.43  ? 428 MET F O   1 
ATOM   19063 C CB  . MET F 1 428 ? -7.609  41.162  47.549  1.00 28.02  ? 428 MET F CB  1 
ATOM   19064 C CG  . MET F 1 428 ? -8.508  42.371  47.645  1.00 34.14  ? 428 MET F CG  1 
ATOM   19065 S SD  . MET F 1 428 ? -9.684  42.178  49.014  1.00 40.54  ? 428 MET F SD  1 
ATOM   19066 C CE  . MET F 1 428 ? -11.129 42.916  48.270  1.00 41.00  ? 428 MET F CE  1 
ATOM   19067 N N   . LYS F 1 429 ? -6.089  38.724  46.291  1.00 33.07  ? 429 LYS F N   1 
ATOM   19068 C CA  . LYS F 1 429 ? -5.233  37.566  46.515  1.00 33.19  ? 429 LYS F CA  1 
ATOM   19069 C C   . LYS F 1 429 ? -3.930  37.681  45.729  1.00 37.68  ? 429 LYS F C   1 
ATOM   19070 O O   . LYS F 1 429 ? -2.858  37.350  46.253  1.00 36.42  ? 429 LYS F O   1 
ATOM   19071 C CB  . LYS F 1 429 ? -5.981  36.283  46.149  1.00 29.30  ? 429 LYS F CB  1 
ATOM   19072 C CG  . LYS F 1 429 ? -7.270  36.099  46.919  1.00 35.79  ? 429 LYS F CG  1 
ATOM   19073 C CD  . LYS F 1 429 ? -7.675  34.651  47.054  1.00 33.16  ? 429 LYS F CD  1 
ATOM   19074 C CE  . LYS F 1 429 ? -8.249  34.126  45.752  1.00 35.95  ? 429 LYS F CE  1 
ATOM   19075 N NZ  . LYS F 1 429 ? -8.032  32.649  45.630  1.00 41.45  ? 429 LYS F NZ  1 
ATOM   19076 N N   . ASP F 1 430 ? -3.997  38.151  44.472  1.00 34.57  ? 430 ASP F N   1 
ATOM   19077 C CA  . ASP F 1 430 ? -2.774  38.338  43.689  1.00 36.81  ? 430 ASP F CA  1 
ATOM   19078 C C   . ASP F 1 430 ? -1.880  39.422  44.300  1.00 39.15  ? 430 ASP F C   1 
ATOM   19079 O O   . ASP F 1 430 ? -0.648  39.292  44.296  1.00 36.14  ? 430 ASP F O   1 
ATOM   19080 C CB  . ASP F 1 430 ? -3.120  38.657  42.230  1.00 39.28  ? 430 ASP F CB  1 
ATOM   19081 C CG  . ASP F 1 430 ? -3.526  37.406  41.422  1.00 39.64  ? 430 ASP F CG  1 
ATOM   19082 O OD1 . ASP F 1 430 ? -2.738  36.441  41.347  1.00 51.84  ? 430 ASP F OD1 1 
ATOM   19083 O OD2 . ASP F 1 430 ? -4.625  37.383  40.843  1.00 42.31  ? 430 ASP F OD2 1 
ATOM   19084 N N   . GLU F 1 431 ? -2.485  40.477  44.869  1.00 35.47  ? 431 GLU F N   1 
ATOM   19085 C CA  . GLU F 1 431 ? -1.715  41.506  45.575  1.00 40.13  ? 431 GLU F CA  1 
ATOM   19086 C C   . GLU F 1 431 ? -0.985  40.927  46.785  1.00 39.57  ? 431 GLU F C   1 
ATOM   19087 O O   . GLU F 1 431 ? 0.194   41.229  47.018  1.00 34.66  ? 431 GLU F O   1 
ATOM   19088 C CB  . GLU F 1 431 ? -2.629  42.650  46.027  1.00 37.34  ? 431 GLU F CB  1 
ATOM   19089 C CG  . GLU F 1 431 ? -3.109  43.581  44.930  1.00 44.20  ? 431 GLU F CG  1 
ATOM   19090 C CD  . GLU F 1 431 ? -2.142  44.733  44.678  1.00 59.92  ? 431 GLU F CD  1 
ATOM   19091 O OE1 . GLU F 1 431 ? -0.994  44.686  45.189  1.00 55.23  ? 431 GLU F OE1 1 
ATOM   19092 O OE2 . GLU F 1 431 ? -2.542  45.697  43.982  1.00 64.13  ? 431 GLU F OE2 1 
ATOM   19093 N N   . ILE F 1 432 ? -1.687  40.115  47.586  1.00 35.01  ? 432 ILE F N   1 
ATOM   19094 C CA  . ILE F 1 432 ? -1.070  39.501  48.761  1.00 33.45  ? 432 ILE F CA  1 
ATOM   19095 C C   . ILE F 1 432 ? 0.125   38.659  48.346  1.00 35.21  ? 432 ILE F C   1 
ATOM   19096 O O   . ILE F 1 432 ? 1.205   38.732  48.952  1.00 32.79  ? 432 ILE F O   1 
ATOM   19097 C CB  . ILE F 1 432 ? -2.094  38.646  49.534  1.00 30.39  ? 432 ILE F CB  1 
ATOM   19098 C CG1 . ILE F 1 432 ? -3.111  39.529  50.260  1.00 34.88  ? 432 ILE F CG1 1 
ATOM   19099 C CG2 . ILE F 1 432 ? -1.366  37.763  50.525  1.00 27.15  ? 432 ILE F CG2 1 
ATOM   19100 C CD1 . ILE F 1 432 ? -4.529  38.952  50.288  1.00 37.53  ? 432 ILE F CD1 1 
ATOM   19101 N N   . ALA F 1 433 ? -0.064  37.822  47.316  1.00 33.06  ? 433 ALA F N   1 
ATOM   19102 C CA  . ALA F 1 433 ? 1.022   36.976  46.834  1.00 34.58  ? 433 ALA F CA  1 
ATOM   19103 C C   . ALA F 1 433 ? 2.211   37.827  46.412  1.00 37.01  ? 433 ALA F C   1 
ATOM   19104 O O   . ALA F 1 433 ? 3.347   37.573  46.820  1.00 41.51  ? 433 ALA F O   1 
ATOM   19105 C CB  . ALA F 1 433 ? 0.530   36.107  45.675  1.00 34.73  ? 433 ALA F CB  1 
ATOM   19106 N N   . THR F 1 434 ? 1.957   38.863  45.610  1.00 36.05  ? 434 THR F N   1 
ATOM   19107 C CA  . THR F 1 434 ? 3.013   39.802  45.259  1.00 38.78  ? 434 THR F CA  1 
ATOM   19108 C C   . THR F 1 434 ? 3.631   40.412  46.507  1.00 39.54  ? 434 THR F C   1 
ATOM   19109 O O   . THR F 1 434 ? 4.852   40.394  46.682  1.00 42.40  ? 434 THR F O   1 
ATOM   19110 C CB  . THR F 1 434 ? 2.457   40.897  44.351  1.00 38.38  ? 434 THR F CB  1 
ATOM   19111 O OG1 . THR F 1 434 ? 2.028   40.315  43.113  1.00 39.21  ? 434 THR F OG1 1 
ATOM   19112 C CG2 . THR F 1 434 ? 3.515   41.975  44.083  1.00 34.97  ? 434 THR F CG2 1 
ATOM   19113 N N   . THR F 1 435 ? 2.797   40.931  47.405  1.00 35.39  ? 435 THR F N   1 
ATOM   19114 C CA  . THR F 1 435 ? 3.336   41.711  48.507  1.00 35.76  ? 435 THR F CA  1 
ATOM   19115 C C   . THR F 1 435 ? 3.933   40.834  49.597  1.00 36.59  ? 435 THR F C   1 
ATOM   19116 O O   . THR F 1 435 ? 5.009   41.140  50.117  1.00 40.47  ? 435 THR F O   1 
ATOM   19117 C CB  . THR F 1 435 ? 2.246   42.593  49.096  1.00 39.77  ? 435 THR F CB  1 
ATOM   19118 O OG1 . THR F 1 435 ? 1.617   43.343  48.046  1.00 42.45  ? 435 THR F OG1 1 
ATOM   19119 C CG2 . THR F 1 435 ? 2.839   43.527  50.120  1.00 37.70  ? 435 THR F CG2 1 
ATOM   19120 N N   . ALA F 1 436 ? 3.234   39.767  49.983  1.00 39.23  ? 436 ALA F N   1 
ATOM   19121 C CA  . ALA F 1 436 ? 3.681   38.908  51.067  1.00 36.89  ? 436 ALA F CA  1 
ATOM   19122 C C   . ALA F 1 436 ? 4.518   37.729  50.590  1.00 36.15  ? 436 ALA F C   1 
ATOM   19123 O O   . ALA F 1 436 ? 5.319   37.207  51.378  1.00 31.09  ? 436 ALA F O   1 
ATOM   19124 C CB  . ALA F 1 436 ? 2.471   38.388  51.863  1.00 32.47  ? 436 ALA F CB  1 
ATOM   19125 N N   . GLY F 1 437 ? 4.347   37.296  49.334  1.00 31.80  ? 437 GLY F N   1 
ATOM   19126 C CA  . GLY F 1 437 ? 5.038   36.124  48.821  1.00 34.90  ? 437 GLY F CA  1 
ATOM   19127 C C   . GLY F 1 437 ? 4.393   34.793  49.163  1.00 34.70  ? 437 GLY F C   1 
ATOM   19128 O O   . GLY F 1 437 ? 3.992   34.572  50.307  1.00 39.50  ? 437 GLY F O   1 
ATOM   19129 N N   . THR F 1 438 ? 4.285   33.892  48.186  1.00 35.61  ? 438 THR F N   1 
ATOM   19130 C CA  . THR F 1 438 ? 3.774   32.553  48.420  1.00 33.26  ? 438 THR F CA  1 
ATOM   19131 C C   . THR F 1 438 ? 4.910   31.552  48.265  1.00 33.34  ? 438 THR F C   1 
ATOM   19132 O O   . THR F 1 438 ? 5.947   31.857  47.678  1.00 41.58  ? 438 THR F O   1 
ATOM   19133 C CB  . THR F 1 438 ? 2.624   32.211  47.460  1.00 35.71  ? 438 THR F CB  1 
ATOM   19134 O OG1 . THR F 1 438 ? 3.019   32.492  46.119  1.00 41.38  ? 438 THR F OG1 1 
ATOM   19135 C CG2 . THR F 1 438 ? 1.386   33.029  47.775  1.00 32.02  ? 438 THR F CG2 1 
ATOM   19136 N N   . LEU F 1 439 ? 4.705   30.355  48.812  1.00 38.63  ? 439 LEU F N   1 
ATOM   19137 C CA  . LEU F 1 439 ? 5.675   29.266  48.717  1.00 44.06  ? 439 LEU F CA  1 
ATOM   19138 C C   . LEU F 1 439 ? 5.468   28.502  47.409  1.00 46.49  ? 439 LEU F C   1 
ATOM   19139 O O   . LEU F 1 439 ? 4.402   27.915  47.182  1.00 46.83  ? 439 LEU F O   1 
ATOM   19140 C CB  . LEU F 1 439 ? 5.551   28.327  49.919  1.00 34.89  ? 439 LEU F CB  1 
ATOM   19141 C CG  . LEU F 1 439 ? 6.060   28.913  51.239  1.00 37.25  ? 439 LEU F CG  1 
ATOM   19142 C CD1 . LEU F 1 439 ? 5.673   28.051  52.432  1.00 32.82  ? 439 LEU F CD1 1 
ATOM   19143 C CD2 . LEU F 1 439 ? 7.581   29.117  51.197  1.00 37.77  ? 439 LEU F CD2 1 
ATOM   19144 N N   . SER F 1 440 ? 6.491   28.503  46.557  1.00 50.01  ? 440 SER F N   1 
ATOM   19145 C CA  . SER F 1 440 ? 6.376   27.952  45.206  1.00 52.51  ? 440 SER F CA  1 
ATOM   19146 C C   . SER F 1 440 ? 6.270   26.430  45.184  1.00 56.24  ? 440 SER F C   1 
ATOM   19147 O O   . SER F 1 440 ? 6.623   25.752  46.156  1.00 53.72  ? 440 SER F O   1 
ATOM   19148 C CB  . SER F 1 440 ? 7.568   28.395  44.362  1.00 51.82  ? 440 SER F CB  1 
ATOM   19149 O OG  . SER F 1 440 ? 8.739   27.711  44.760  1.00 50.55  ? 440 SER F OG  1 
ATOM   19150 N N   . PRO G 1 2   ? 31.640  -3.626  80.491  1.00 34.56  ? 2   PRO G N   1 
ATOM   19151 C CA  . PRO G 1 2   ? 30.574  -3.504  79.484  1.00 37.92  ? 2   PRO G CA  1 
ATOM   19152 C C   . PRO G 1 2   ? 30.422  -2.074  78.975  1.00 32.85  ? 2   PRO G C   1 
ATOM   19153 O O   . PRO G 1 2   ? 31.194  -1.193  79.393  1.00 28.57  ? 2   PRO G O   1 
ATOM   19154 C CB  . PRO G 1 2   ? 29.311  -3.948  80.251  1.00 42.45  ? 2   PRO G CB  1 
ATOM   19155 C CG  . PRO G 1 2   ? 29.825  -4.523  81.602  1.00 32.48  ? 2   PRO G CG  1 
ATOM   19156 C CD  . PRO G 1 2   ? 31.088  -3.766  81.846  1.00 34.83  ? 2   PRO G CD  1 
ATOM   19157 N N   . LYS G 1 3   ? 29.436  -1.836  78.106  1.00 34.02  ? 3   LYS G N   1 
ATOM   19158 C CA  . LYS G 1 3   ? 29.198  -0.500  77.569  1.00 31.84  ? 3   LYS G CA  1 
ATOM   19159 C C   . LYS G 1 3   ? 27.703  -0.188  77.536  1.00 31.05  ? 3   LYS G C   1 
ATOM   19160 O O   . LYS G 1 3   ? 26.861  -1.080  77.376  1.00 31.03  ? 3   LYS G O   1 
ATOM   19161 C CB  . LYS G 1 3   ? 29.833  -0.360  76.168  1.00 26.68  ? 3   LYS G CB  1 
ATOM   19162 C CG  . LYS G 1 3   ? 28.901  -0.610  74.996  1.00 29.19  ? 3   LYS G CG  1 
ATOM   19163 C CD  . LYS G 1 3   ? 29.697  -0.804  73.694  1.00 30.17  ? 3   LYS G CD  1 
ATOM   19164 C CE  . LYS G 1 3   ? 28.972  -1.752  72.708  1.00 28.27  ? 3   LYS G CE  1 
ATOM   19165 N NZ  . LYS G 1 3   ? 29.416  -3.173  72.754  1.00 22.14  ? 3   LYS G NZ  1 
ATOM   19166 N N   . ILE G 1 4   ? 27.381  1.093   77.721  1.00 27.07  ? 4   ILE G N   1 
ATOM   19167 C CA  . ILE G 1 4   ? 26.016  1.608   77.625  1.00 27.71  ? 4   ILE G CA  1 
ATOM   19168 C C   . ILE G 1 4   ? 25.837  2.191   76.225  1.00 31.42  ? 4   ILE G C   1 
ATOM   19169 O O   . ILE G 1 4   ? 26.470  3.197   75.880  1.00 26.47  ? 4   ILE G O   1 
ATOM   19170 C CB  . ILE G 1 4   ? 25.732  2.660   78.706  1.00 31.53  ? 4   ILE G CB  1 
ATOM   19171 C CG1 . ILE G 1 4   ? 25.900  2.078   80.107  1.00 30.27  ? 4   ILE G CG1 1 
ATOM   19172 C CG2 . ILE G 1 4   ? 24.322  3.282   78.570  1.00 27.68  ? 4   ILE G CG2 1 
ATOM   19173 C CD1 . ILE G 1 4   ? 25.641  3.129   81.187  1.00 34.46  ? 4   ILE G CD1 1 
ATOM   19174 N N   . ILE G 1 5   ? 24.986  1.554   75.415  1.00 29.87  ? 5   ILE G N   1 
ATOM   19175 C CA  . ILE G 1 5   ? 24.733  1.975   74.040  1.00 26.27  ? 5   ILE G CA  1 
ATOM   19176 C C   . ILE G 1 5   ? 23.622  3.009   74.050  1.00 31.08  ? 5   ILE G C   1 
ATOM   19177 O O   . ILE G 1 5   ? 22.504  2.715   74.495  1.00 29.36  ? 5   ILE G O   1 
ATOM   19178 C CB  . ILE G 1 5   ? 24.352  0.786   73.148  1.00 29.17  ? 5   ILE G CB  1 
ATOM   19179 C CG1 . ILE G 1 5   ? 25.373  -0.331  73.295  1.00 23.82  ? 5   ILE G CG1 1 
ATOM   19180 C CG2 . ILE G 1 5   ? 24.199  1.252   71.695  1.00 24.82  ? 5   ILE G CG2 1 
ATOM   19181 C CD1 . ILE G 1 5   ? 24.981  -1.584  72.617  1.00 25.57  ? 5   ILE G CD1 1 
ATOM   19182 N N   . LEU G 1 6   ? 23.912  4.191   73.491  1.00 28.07  ? 6   LEU G N   1 
ATOM   19183 C CA  . LEU G 1 6   ? 23.128  5.410   73.685  1.00 25.59  ? 6   LEU G CA  1 
ATOM   19184 C C   . LEU G 1 6   ? 22.743  6.026   72.345  1.00 30.35  ? 6   LEU G C   1 
ATOM   19185 O O   . LEU G 1 6   ? 23.414  6.944   71.853  1.00 28.86  ? 6   LEU G O   1 
ATOM   19186 C CB  . LEU G 1 6   ? 23.924  6.415   74.519  1.00 26.78  ? 6   LEU G CB  1 
ATOM   19187 C CG  . LEU G 1 6   ? 23.346  7.366   75.574  1.00 35.62  ? 6   LEU G CG  1 
ATOM   19188 C CD1 . LEU G 1 6   ? 23.494  8.833   75.123  1.00 28.55  ? 6   LEU G CD1 1 
ATOM   19189 C CD2 . LEU G 1 6   ? 21.897  7.033   76.014  1.00 36.27  ? 6   LEU G CD2 1 
ATOM   19190 N N   . PRO G 1 7   ? 21.652  5.584   71.743  1.00 29.00  ? 7   PRO G N   1 
ATOM   19191 C CA  . PRO G 1 7   ? 21.266  6.143   70.435  1.00 29.18  ? 7   PRO G CA  1 
ATOM   19192 C C   . PRO G 1 7   ? 20.626  7.518   70.569  1.00 32.17  ? 7   PRO G C   1 
ATOM   19193 O O   . PRO G 1 7   ? 19.423  7.720   70.345  1.00 34.92  ? 7   PRO G O   1 
ATOM   19194 C CB  . PRO G 1 7   ? 20.285  5.092   69.907  1.00 28.53  ? 7   PRO G CB  1 
ATOM   19195 C CG  . PRO G 1 7   ? 19.629  4.570   71.140  1.00 36.21  ? 7   PRO G CG  1 
ATOM   19196 C CD  . PRO G 1 7   ? 20.713  4.553   72.204  1.00 30.62  ? 7   PRO G CD  1 
ATOM   19197 N N   . ASN G 1 8   ? 21.429  8.506   70.941  1.00 27.19  ? 8   ASN G N   1 
ATOM   19198 C CA  . ASN G 1 8   ? 20.908  9.869   71.082  1.00 33.22  ? 8   ASN G CA  1 
ATOM   19199 C C   . ASN G 1 8   ? 21.019  10.605  69.738  1.00 35.73  ? 8   ASN G C   1 
ATOM   19200 O O   . ASN G 1 8   ? 21.840  11.502  69.544  1.00 35.86  ? 8   ASN G O   1 
ATOM   19201 C CB  . ASN G 1 8   ? 21.641  10.599  72.202  1.00 29.61  ? 8   ASN G CB  1 
ATOM   19202 C CG  . ASN G 1 8   ? 23.130  10.628  71.987  1.00 29.63  ? 8   ASN G CG  1 
ATOM   19203 O OD1 . ASN G 1 8   ? 23.701  9.671   71.474  1.00 27.88  ? 8   ASN G OD1 1 
ATOM   19204 N ND2 . ASN G 1 8   ? 23.768  11.740  72.346  1.00 29.29  ? 8   ASN G ND2 1 
ATOM   19205 N N   . PHE G 1 9   ? 20.162  10.188  68.797  1.00 38.62  ? 9   PHE G N   1 
ATOM   19206 C CA  . PHE G 1 9   ? 20.104  10.764  67.454  1.00 38.70  ? 9   PHE G CA  1 
ATOM   19207 C C   . PHE G 1 9   ? 20.192  12.279  67.468  1.00 46.49  ? 9   PHE G C   1 
ATOM   19208 O O   . PHE G 1 9   ? 21.034  12.890  66.802  1.00 52.14  ? 9   PHE G O   1 
ATOM   19209 C CB  . PHE G 1 9   ? 18.783  10.403  66.765  1.00 41.02  ? 9   PHE G CB  1 
ATOM   19210 C CG  . PHE G 1 9   ? 18.489  8.943   66.700  1.00 46.93  ? 9   PHE G CG  1 
ATOM   19211 C CD1 . PHE G 1 9   ? 17.178  8.497   66.717  1.00 44.50  ? 9   PHE G CD1 1 
ATOM   19212 C CD2 . PHE G 1 9   ? 19.512  8.016   66.587  1.00 49.49  ? 9   PHE G CD2 1 
ATOM   19213 C CE1 . PHE G 1 9   ? 16.891  7.153   66.639  1.00 48.91  ? 9   PHE G CE1 1 
ATOM   19214 C CE2 . PHE G 1 9   ? 19.227  6.666   66.514  1.00 48.10  ? 9   PHE G CE2 1 
ATOM   19215 C CZ  . PHE G 1 9   ? 17.916  6.238   66.538  1.00 43.89  ? 9   PHE G CZ  1 
ATOM   19216 N N   . ARG G 1 10  ? 19.280  12.890  68.210  1.00 48.99  ? 10  ARG G N   1 
ATOM   19217 C CA  . ARG G 1 10  ? 18.967  14.304  68.071  1.00 49.32  ? 10  ARG G CA  1 
ATOM   19218 C C   . ARG G 1 10  ? 18.856  14.844  69.486  1.00 49.94  ? 10  ARG G C   1 
ATOM   19219 O O   . ARG G 1 10  ? 17.946  14.463  70.228  1.00 56.28  ? 10  ARG G O   1 
ATOM   19220 C CB  . ARG G 1 10  ? 17.674  14.470  67.261  1.00 50.81  ? 10  ARG G CB  1 
ATOM   19221 C CG  . ARG G 1 10  ? 16.768  15.622  67.616  1.00 60.00  ? 10  ARG G CG  1 
ATOM   19222 C CD  . ARG G 1 10  ? 17.317  16.929  67.096  1.00 68.35  ? 10  ARG G CD  1 
ATOM   19223 N NE  . ARG G 1 10  ? 17.071  18.013  68.036  1.00 65.92  ? 10  ARG G NE  1 
ATOM   19224 C CZ  . ARG G 1 10  ? 17.564  19.233  67.902  1.00 66.25  ? 10  ARG G CZ  1 
ATOM   19225 N NH1 . ARG G 1 10  ? 18.338  19.554  66.875  1.00 69.72  ? 10  ARG G NH1 1 
ATOM   19226 N NH2 . ARG G 1 10  ? 17.285  20.149  68.826  1.00 63.90  ? 10  ARG G NH2 1 
ATOM   19227 N N   . ALA G 1 11  ? 19.803  15.682  69.880  1.00 46.17  ? 11  ALA G N   1 
ATOM   19228 C CA  . ALA G 1 11  ? 19.819  16.157  71.250  1.00 53.13  ? 11  ALA G CA  1 
ATOM   19229 C C   . ALA G 1 11  ? 19.437  17.633  71.366  1.00 56.92  ? 11  ALA G C   1 
ATOM   19230 O O   . ALA G 1 11  ? 18.330  17.977  71.811  1.00 48.38  ? 11  ALA G O   1 
ATOM   19231 C CB  . ALA G 1 11  ? 21.174  15.910  71.854  1.00 52.89  ? 11  ALA G CB  1 
ATOM   19232 N N   . SER G 1 29  ? 5.357   5.503   71.455  1.00 58.71  ? 29  SER G N   1 
ATOM   19233 C CA  . SER G 1 29  ? 5.651   4.969   70.123  1.00 65.92  ? 29  SER G CA  1 
ATOM   19234 C C   . SER G 1 29  ? 5.105   3.554   69.897  1.00 65.10  ? 29  SER G C   1 
ATOM   19235 O O   . SER G 1 29  ? 4.531   2.932   70.796  1.00 68.72  ? 29  SER G O   1 
ATOM   19236 C CB  . SER G 1 29  ? 7.163   4.971   69.867  1.00 58.87  ? 29  SER G CB  1 
ATOM   19237 O OG  . SER G 1 29  ? 7.442   4.669   68.508  1.00 54.53  ? 29  SER G OG  1 
ATOM   19238 N N   . SER G 1 30  ? 5.286   3.063   68.672  1.00 59.65  ? 30  SER G N   1 
ATOM   19239 C CA  . SER G 1 30  ? 4.951   1.691   68.313  1.00 54.65  ? 30  SER G CA  1 
ATOM   19240 C C   . SER G 1 30  ? 6.126   1.084   67.561  1.00 50.99  ? 30  SER G C   1 
ATOM   19241 O O   . SER G 1 30  ? 6.394   -0.119  67.667  1.00 47.94  ? 30  SER G O   1 
ATOM   19242 C CB  . SER G 1 30  ? 3.681   1.643   67.460  1.00 55.11  ? 30  SER G CB  1 
ATOM   19243 O OG  . SER G 1 30  ? 3.027   0.388   67.576  1.00 61.67  ? 30  SER G OG  1 
ATOM   19244 N N   . THR G 1 31  ? 6.839   1.932   66.819  1.00 42.74  ? 31  THR G N   1 
ATOM   19245 C CA  . THR G 1 31  ? 7.942   1.501   65.978  1.00 42.18  ? 31  THR G CA  1 
ATOM   19246 C C   . THR G 1 31  ? 9.128   1.023   66.828  1.00 40.83  ? 31  THR G C   1 
ATOM   19247 O O   . THR G 1 31  ? 9.162   1.191   68.051  1.00 43.02  ? 31  THR G O   1 
ATOM   19248 C CB  . THR G 1 31  ? 8.357   2.632   65.031  1.00 44.44  ? 31  THR G CB  1 
ATOM   19249 O OG1 . THR G 1 31  ? 8.600   3.837   65.769  1.00 47.33  ? 31  THR G OG1 1 
ATOM   19250 C CG2 . THR G 1 31  ? 7.259   2.889   64.007  1.00 37.56  ? 31  THR G CG2 1 
ATOM   19251 N N   . ASP G 1 32  ? 10.112  0.399   66.159  1.00 35.96  ? 32  ASP G N   1 
ATOM   19252 C CA  . ASP G 1 32  ? 11.241  -0.251  66.828  1.00 38.07  ? 32  ASP G CA  1 
ATOM   19253 C C   . ASP G 1 32  ? 12.570  0.213   66.240  1.00 35.51  ? 32  ASP G C   1 
ATOM   19254 O O   . ASP G 1 32  ? 13.558  -0.527  66.241  1.00 30.67  ? 32  ASP G O   1 
ATOM   19255 C CB  . ASP G 1 32  ? 11.106  -1.784  66.774  1.00 32.19  ? 32  ASP G CB  1 
ATOM   19256 C CG  . ASP G 1 32  ? 11.273  -2.374  65.356  1.00 36.31  ? 32  ASP G CG  1 
ATOM   19257 O OD1 . ASP G 1 32  ? 11.237  -1.633  64.345  1.00 31.20  ? 32  ASP G OD1 1 
ATOM   19258 O OD2 . ASP G 1 32  ? 11.403  -3.617  65.252  1.00 38.88  ? 32  ASP G OD2 1 
ATOM   19259 N N   . THR G 1 33  ? 12.603  1.466   65.785  1.00 34.68  ? 33  THR G N   1 
ATOM   19260 C CA  . THR G 1 33  ? 13.709  1.982   64.985  1.00 32.90  ? 33  THR G CA  1 
ATOM   19261 C C   . THR G 1 33  ? 15.059  1.835   65.688  1.00 33.14  ? 33  THR G C   1 
ATOM   19262 O O   . THR G 1 33  ? 16.058  1.467   65.057  1.00 35.25  ? 33  THR G O   1 
ATOM   19263 C CB  . THR G 1 33  ? 13.411  3.447   64.644  1.00 38.32  ? 33  THR G CB  1 
ATOM   19264 O OG1 . THR G 1 33  ? 12.176  3.507   63.923  1.00 34.87  ? 33  THR G OG1 1 
ATOM   19265 C CG2 . THR G 1 33  ? 14.507  4.077   63.798  1.00 38.66  ? 33  THR G CG2 1 
ATOM   19266 N N   . THR G 1 34  ? 15.117  2.110   66.988  1.00 35.28  ? 34  THR G N   1 
ATOM   19267 C CA  . THR G 1 34  ? 16.395  2.039   67.687  1.00 37.33  ? 34  THR G CA  1 
ATOM   19268 C C   . THR G 1 34  ? 16.783  0.624   68.084  1.00 35.51  ? 34  THR G C   1 
ATOM   19269 O O   . THR G 1 34  ? 17.877  0.434   68.629  1.00 31.96  ? 34  THR G O   1 
ATOM   19270 C CB  . THR G 1 34  ? 16.380  2.925   68.931  1.00 34.36  ? 34  THR G CB  1 
ATOM   19271 O OG1 . THR G 1 34  ? 15.576  2.309   69.937  1.00 39.04  ? 34  THR G OG1 1 
ATOM   19272 C CG2 . THR G 1 34  ? 15.821  4.276   68.596  1.00 40.74  ? 34  THR G CG2 1 
ATOM   19273 N N   . ALA G 1 35  ? 15.936  -0.371  67.810  1.00 33.23  ? 35  ALA G N   1 
ATOM   19274 C CA  . ALA G 1 35  ? 16.270  -1.743  68.176  1.00 27.51  ? 35  ALA G CA  1 
ATOM   19275 C C   . ALA G 1 35  ? 17.498  -2.250  67.435  1.00 31.00  ? 35  ALA G C   1 
ATOM   19276 O O   . ALA G 1 35  ? 18.191  -3.151  67.925  1.00 32.02  ? 35  ALA G O   1 
ATOM   19277 C CB  . ALA G 1 35  ? 15.087  -2.654  67.879  1.00 37.27  ? 35  ALA G CB  1 
ATOM   19278 N N   . ARG G 1 36  ? 17.771  -1.705  66.246  1.00 23.88  ? 36  ARG G N   1 
ATOM   19279 C CA  . ARG G 1 36  ? 18.877  -2.193  65.436  1.00 30.04  ? 36  ARG G CA  1 
ATOM   19280 C C   . ARG G 1 36  ? 20.216  -2.061  66.147  1.00 24.49  ? 36  ARG G C   1 
ATOM   19281 O O   . ARG G 1 36  ? 21.165  -2.743  65.774  1.00 27.62  ? 36  ARG G O   1 
ATOM   19282 C CB  . ARG G 1 36  ? 18.915  -1.447  64.098  1.00 21.23  ? 36  ARG G CB  1 
ATOM   19283 C CG  . ARG G 1 36  ? 19.521  -0.039  64.217  1.00 28.48  ? 36  ARG G CG  1 
ATOM   19284 C CD  . ARG G 1 36  ? 18.850  0.955   63.295  1.00 25.11  ? 36  ARG G CD  1 
ATOM   19285 N NE  . ARG G 1 36  ? 19.348  0.798   61.941  1.00 23.05  ? 36  ARG G NE  1 
ATOM   19286 C CZ  . ARG G 1 36  ? 20.469  1.348   61.487  1.00 29.88  ? 36  ARG G CZ  1 
ATOM   19287 N NH1 . ARG G 1 36  ? 21.243  2.096   62.263  1.00 25.68  ? 36  ARG G NH1 1 
ATOM   19288 N NH2 . ARG G 1 36  ? 20.819  1.151   60.219  1.00 26.35  ? 36  ARG G NH2 1 
ATOM   19289 N N   . PHE G 1 37  ? 20.323  -1.212  67.155  1.00 24.33  ? 37  PHE G N   1 
ATOM   19290 C CA  . PHE G 1 37  ? 21.622  -1.002  67.774  1.00 23.06  ? 37  PHE G CA  1 
ATOM   19291 C C   . PHE G 1 37  ? 21.962  -2.100  68.777  1.00 24.95  ? 37  PHE G C   1 
ATOM   19292 O O   . PHE G 1 37  ? 23.098  -2.157  69.258  1.00 25.42  ? 37  PHE G O   1 
ATOM   19293 C CB  . PHE G 1 37  ? 21.655  0.411   68.382  1.00 21.27  ? 37  PHE G CB  1 
ATOM   19294 C CG  . PHE G 1 37  ? 21.462  1.509   67.340  1.00 22.45  ? 37  PHE G CG  1 
ATOM   19295 C CD1 . PHE G 1 37  ? 22.431  1.741   66.365  1.00 22.91  ? 37  PHE G CD1 1 
ATOM   19296 C CD2 . PHE G 1 37  ? 20.299  2.256   67.298  1.00 26.03  ? 37  PHE G CD2 1 
ATOM   19297 C CE1 . PHE G 1 37  ? 22.251  2.727   65.390  1.00 23.50  ? 37  PHE G CE1 1 
ATOM   19298 C CE2 . PHE G 1 37  ? 20.112  3.253   66.330  1.00 30.01  ? 37  PHE G CE2 1 
ATOM   19299 C CZ  . PHE G 1 37  ? 21.078  3.481   65.370  1.00 21.29  ? 37  PHE G CZ  1 
ATOM   19300 N N   . LEU G 1 38  ? 21.020  -3.013  69.048  1.00 31.07  ? 38  LEU G N   1 
ATOM   19301 C CA  . LEU G 1 38  ? 21.320  -4.214  69.829  1.00 23.88  ? 38  LEU G CA  1 
ATOM   19302 C C   . LEU G 1 38  ? 22.429  -5.039  69.199  1.00 25.16  ? 38  LEU G C   1 
ATOM   19303 O O   . LEU G 1 38  ? 23.135  -5.761  69.906  1.00 29.50  ? 38  LEU G O   1 
ATOM   19304 C CB  . LEU G 1 38  ? 20.063  -5.070  69.976  1.00 26.00  ? 38  LEU G CB  1 
ATOM   19305 C CG  . LEU G 1 38  ? 19.470  -5.211  71.376  1.00 31.13  ? 38  LEU G CG  1 
ATOM   19306 C CD1 . LEU G 1 38  ? 18.237  -6.075  71.303  1.00 31.12  ? 38  LEU G CD1 1 
ATOM   19307 C CD2 . LEU G 1 38  ? 20.472  -5.780  72.363  1.00 30.71  ? 38  LEU G CD2 1 
ATOM   19308 N N   . TRP G 1 39  ? 22.617  -4.942  67.878  1.00 25.43  ? 39  TRP G N   1 
ATOM   19309 C CA  . TRP G 1 39  ? 23.700  -5.675  67.232  1.00 22.79  ? 39  TRP G CA  1 
ATOM   19310 C C   . TRP G 1 39  ? 25.092  -5.202  67.666  1.00 26.13  ? 39  TRP G C   1 
ATOM   19311 O O   . TRP G 1 39  ? 26.087  -5.897  67.389  1.00 25.40  ? 39  TRP G O   1 
ATOM   19312 C CB  . TRP G 1 39  ? 23.541  -5.585  65.714  1.00 23.07  ? 39  TRP G CB  1 
ATOM   19313 C CG  . TRP G 1 39  ? 22.375  -6.406  65.221  1.00 26.65  ? 39  TRP G CG  1 
ATOM   19314 C CD1 . TRP G 1 39  ? 21.084  -5.978  65.032  1.00 22.68  ? 39  TRP G CD1 1 
ATOM   19315 C CD2 . TRP G 1 39  ? 22.385  -7.803  64.892  1.00 20.30  ? 39  TRP G CD2 1 
ATOM   19316 N NE1 . TRP G 1 39  ? 20.301  -7.019  64.598  1.00 24.16  ? 39  TRP G NE1 1 
ATOM   19317 C CE2 . TRP G 1 39  ? 21.075  -8.150  64.505  1.00 24.38  ? 39  TRP G CE2 1 
ATOM   19318 C CE3 . TRP G 1 39  ? 23.374  -8.791  64.886  1.00 25.00  ? 39  TRP G CE3 1 
ATOM   19319 C CZ2 . TRP G 1 39  ? 20.725  -9.455  64.114  1.00 21.79  ? 39  TRP G CZ2 1 
ATOM   19320 C CZ3 . TRP G 1 39  ? 23.031  -10.088 64.481  1.00 22.44  ? 39  TRP G CZ3 1 
ATOM   19321 C CH2 . TRP G 1 39  ? 21.718  -10.400 64.101  1.00 22.03  ? 39  TRP G CH2 1 
ATOM   19322 N N   . HIS G 1 40  ? 25.185  -4.063  68.355  1.00 21.96  ? 40  HIS G N   1 
ATOM   19323 C CA  . HIS G 1 40  ? 26.438  -3.636  68.967  1.00 23.61  ? 40  HIS G CA  1 
ATOM   19324 C C   . HIS G 1 40  ? 26.782  -4.413  70.243  1.00 26.27  ? 40  HIS G C   1 
ATOM   19325 O O   . HIS G 1 40  ? 27.944  -4.415  70.651  1.00 23.55  ? 40  HIS G O   1 
ATOM   19326 C CB  . HIS G 1 40  ? 26.380  -2.144  69.322  1.00 23.51  ? 40  HIS G CB  1 
ATOM   19327 C CG  . HIS G 1 40  ? 26.614  -1.219  68.166  1.00 24.31  ? 40  HIS G CG  1 
ATOM   19328 N ND1 . HIS G 1 40  ? 27.806  -1.166  67.480  1.00 21.43  ? 40  HIS G ND1 1 
ATOM   19329 C CD2 . HIS G 1 40  ? 25.811  -0.286  67.596  1.00 23.56  ? 40  HIS G CD2 1 
ATOM   19330 C CE1 . HIS G 1 40  ? 27.727  -0.245  66.535  1.00 24.09  ? 40  HIS G CE1 1 
ATOM   19331 N NE2 . HIS G 1 40  ? 26.524  0.297   66.578  1.00 21.29  ? 40  HIS G NE2 1 
ATOM   19332 N N   . ALA G 1 41  ? 25.812  -5.059  70.886  1.00 25.99  ? 41  ALA G N   1 
ATOM   19333 C CA  . ALA G 1 41  ? 25.996  -5.484  72.264  1.00 29.44  ? 41  ALA G CA  1 
ATOM   19334 C C   . ALA G 1 41  ? 27.002  -6.626  72.376  1.00 29.10  ? 41  ALA G C   1 
ATOM   19335 O O   . ALA G 1 41  ? 27.067  -7.513  71.522  1.00 33.07  ? 41  ALA G O   1 
ATOM   19336 C CB  . ALA G 1 41  ? 24.653  -5.899  72.871  1.00 33.76  ? 41  ALA G CB  1 
ATOM   19337 N N   . GLU G 1 42  ? 27.837  -6.553  73.407  1.00 32.02  ? 42  GLU G N   1 
ATOM   19338 C CA  . GLU G 1 42  ? 28.554  -7.691  73.960  1.00 31.90  ? 42  GLU G CA  1 
ATOM   19339 C C   . GLU G 1 42  ? 27.944  -7.989  75.319  1.00 36.51  ? 42  GLU G C   1 
ATOM   19340 O O   . GLU G 1 42  ? 27.079  -7.247  75.802  1.00 34.11  ? 42  GLU G O   1 
ATOM   19341 C CB  . GLU G 1 42  ? 30.058  -7.417  74.089  1.00 32.70  ? 42  GLU G CB  1 
ATOM   19342 C CG  . GLU G 1 42  ? 30.790  -7.129  72.758  1.00 35.43  ? 42  GLU G CG  1 
ATOM   19343 C CD  . GLU G 1 42  ? 31.052  -8.392  71.902  1.00 44.14  ? 42  GLU G CD  1 
ATOM   19344 O OE1 . GLU G 1 42  ? 30.644  -9.514  72.311  1.00 40.30  ? 42  GLU G OE1 1 
ATOM   19345 O OE2 . GLU G 1 42  ? 31.667  -8.260  70.811  1.00 41.55  ? 42  GLU G OE2 1 
ATOM   19346 N N   . ASP G 1 43  ? 28.399  -9.075  75.940  1.00 36.47  ? 43  ASP G N   1 
ATOM   19347 C CA  . ASP G 1 43  ? 27.755  -9.532  77.165  1.00 35.05  ? 43  ASP G CA  1 
ATOM   19348 C C   . ASP G 1 43  ? 27.864  -8.472  78.258  1.00 39.66  ? 43  ASP G C   1 
ATOM   19349 O O   . ASP G 1 43  ? 28.878  -7.773  78.386  1.00 36.02  ? 43  ASP G O   1 
ATOM   19350 C CB  . ASP G 1 43  ? 28.368  -10.857 77.626  1.00 41.11  ? 43  ASP G CB  1 
ATOM   19351 C CG  . ASP G 1 43  ? 29.599  -10.667 78.474  1.00 46.29  ? 43  ASP G CG  1 
ATOM   19352 O OD1 . ASP G 1 43  ? 30.636  -10.227 77.931  1.00 59.41  ? 43  ASP G OD1 1 
ATOM   19353 O OD2 . ASP G 1 43  ? 29.541  -10.967 79.684  1.00 57.64  ? 43  ASP G OD2 1 
ATOM   19354 N N   . GLY G 1 44  ? 26.791  -8.330  79.027  1.00 36.76  ? 44  GLY G N   1 
ATOM   19355 C CA  . GLY G 1 44  ? 26.762  -7.370  80.103  1.00 37.30  ? 44  GLY G CA  1 
ATOM   19356 C C   . GLY G 1 44  ? 26.362  -5.971  79.708  1.00 37.89  ? 44  GLY G C   1 
ATOM   19357 O O   . GLY G 1 44  ? 26.327  -5.087  80.581  1.00 40.23  ? 44  GLY G O   1 
ATOM   19358 N N   . ASP G 1 45  ? 26.060  -5.738  78.432  1.00 32.81  ? 45  ASP G N   1 
ATOM   19359 C CA  . ASP G 1 45  ? 25.841  -4.385  77.950  1.00 32.57  ? 45  ASP G CA  1 
ATOM   19360 C C   . ASP G 1 45  ? 24.426  -3.928  78.271  1.00 32.16  ? 45  ASP G C   1 
ATOM   19361 O O   . ASP G 1 45  ? 23.502  -4.724  78.448  1.00 34.90  ? 45  ASP G O   1 
ATOM   19362 C CB  . ASP G 1 45  ? 26.068  -4.277  76.434  1.00 30.36  ? 45  ASP G CB  1 
ATOM   19363 C CG  . ASP G 1 45  ? 27.532  -4.106  76.055  1.00 32.16  ? 45  ASP G CG  1 
ATOM   19364 O OD1 . ASP G 1 45  ? 28.405  -4.125  76.947  1.00 32.53  ? 45  ASP G OD1 1 
ATOM   19365 O OD2 . ASP G 1 45  ? 27.818  -3.974  74.838  1.00 34.81  ? 45  ASP G OD2 1 
ATOM   19366 N N   . VAL G 1 46  ? 24.269  -2.613  78.320  1.00 34.07  ? 46  VAL G N   1 
ATOM   19367 C CA  . VAL G 1 46  ? 22.979  -1.960  78.457  1.00 30.57  ? 46  VAL G CA  1 
ATOM   19368 C C   . VAL G 1 46  ? 22.709  -1.196  77.169  1.00 29.93  ? 46  VAL G C   1 
ATOM   19369 O O   . VAL G 1 46  ? 23.550  -0.411  76.718  1.00 34.17  ? 46  VAL G O   1 
ATOM   19370 C CB  . VAL G 1 46  ? 22.966  -1.015  79.668  1.00 30.72  ? 46  VAL G CB  1 
ATOM   19371 C CG1 . VAL G 1 46  ? 21.641  -0.315  79.789  1.00 35.36  ? 46  VAL G CG1 1 
ATOM   19372 C CG2 . VAL G 1 46  ? 23.302  -1.789  80.939  1.00 36.65  ? 46  VAL G CG2 1 
ATOM   19373 N N   . LEU G 1 47  ? 21.547  -1.427  76.575  1.00 30.43  ? 47  LEU G N   1 
ATOM   19374 C CA  . LEU G 1 47  ? 21.067  -0.636  75.457  1.00 27.29  ? 47  LEU G CA  1 
ATOM   19375 C C   . LEU G 1 47  ? 19.939  0.242   75.972  1.00 31.26  ? 47  LEU G C   1 
ATOM   19376 O O   . LEU G 1 47  ? 18.998  -0.263  76.580  1.00 34.22  ? 47  LEU G O   1 
ATOM   19377 C CB  . LEU G 1 47  ? 20.576  -1.536  74.316  1.00 25.15  ? 47  LEU G CB  1 
ATOM   19378 C CG  . LEU G 1 47  ? 19.788  -0.809  73.213  1.00 27.59  ? 47  LEU G CG  1 
ATOM   19379 C CD1 . LEU G 1 47  ? 20.720  0.092   72.402  1.00 26.18  ? 47  LEU G CD1 1 
ATOM   19380 C CD2 . LEU G 1 47  ? 19.022  -1.768  72.295  1.00 23.29  ? 47  LEU G CD2 1 
ATOM   19381 N N   . VAL G 1 48  ? 20.026  1.549   75.746  1.00 31.24  ? 48  VAL G N   1 
ATOM   19382 C CA  . VAL G 1 48  ? 18.972  2.473   76.162  1.00 28.74  ? 48  VAL G CA  1 
ATOM   19383 C C   . VAL G 1 48  ? 18.096  2.762   74.943  1.00 37.33  ? 48  VAL G C   1 
ATOM   19384 O O   . VAL G 1 48  ? 18.602  3.212   73.910  1.00 35.64  ? 48  VAL G O   1 
ATOM   19385 C CB  . VAL G 1 48  ? 19.560  3.765   76.750  1.00 29.67  ? 48  VAL G CB  1 
ATOM   19386 C CG1 . VAL G 1 48  ? 18.462  4.687   77.180  1.00 28.89  ? 48  VAL G CG1 1 
ATOM   19387 C CG2 . VAL G 1 48  ? 20.490  3.461   77.919  1.00 32.49  ? 48  VAL G CG2 1 
ATOM   19388 N N   . ILE G 1 49  ? 16.793  2.481   75.035  1.00 34.55  ? 49  ILE G N   1 
ATOM   19389 C CA  . ILE G 1 49  ? 15.894  2.693   73.893  1.00 40.47  ? 49  ILE G CA  1 
ATOM   19390 C C   . ILE G 1 49  ? 14.781  3.691   74.221  1.00 39.39  ? 49  ILE G C   1 
ATOM   19391 O O   . ILE G 1 49  ? 14.232  3.677   75.334  1.00 40.21  ? 49  ILE G O   1 
ATOM   19392 C CB  . ILE G 1 49  ? 15.280  1.368   73.398  1.00 37.83  ? 49  ILE G CB  1 
ATOM   19393 C CG1 . ILE G 1 49  ? 14.207  0.877   74.364  1.00 41.21  ? 49  ILE G CG1 1 
ATOM   19394 C CG2 . ILE G 1 49  ? 16.306  0.290   73.276  1.00 35.10  ? 49  ILE G CG2 1 
ATOM   19395 C CD1 . ILE G 1 49  ? 13.426  -0.268  73.845  1.00 41.98  ? 49  ILE G CD1 1 
ATOM   19396 N N   . PRO G 1 50  ? 14.411  4.569   73.290  1.00 36.52  ? 50  PRO G N   1 
ATOM   19397 C CA  . PRO G 1 50  ? 13.219  5.399   73.495  1.00 42.26  ? 50  PRO G CA  1 
ATOM   19398 C C   . PRO G 1 50  ? 11.951  4.790   72.919  1.00 42.63  ? 50  PRO G C   1 
ATOM   19399 O O   . PRO G 1 50  ? 10.852  5.194   73.306  1.00 45.44  ? 50  PRO G O   1 
ATOM   19400 C CB  . PRO G 1 50  ? 13.578  6.693   72.765  1.00 42.95  ? 50  PRO G CB  1 
ATOM   19401 C CG  . PRO G 1 50  ? 14.386  6.207   71.616  1.00 40.13  ? 50  PRO G CG  1 
ATOM   19402 C CD  . PRO G 1 50  ? 15.191  5.032   72.131  1.00 39.82  ? 50  PRO G CD  1 
ATOM   19403 N N   . ASP G 1 51  ? 12.073  3.851   71.976  1.00 44.57  ? 51  ASP G N   1 
ATOM   19404 C CA  . ASP G 1 51  ? 10.885  3.244   71.381  1.00 45.64  ? 51  ASP G CA  1 
ATOM   19405 C C   . ASP G 1 51  ? 10.592  1.914   72.064  1.00 45.88  ? 51  ASP G C   1 
ATOM   19406 O O   . ASP G 1 51  ? 10.952  1.722   73.227  1.00 49.56  ? 51  ASP G O   1 
ATOM   19407 C CB  . ASP G 1 51  ? 11.042  3.061   69.864  1.00 43.64  ? 51  ASP G CB  1 
ATOM   19408 C CG  . ASP G 1 51  ? 12.444  2.636   69.454  1.00 45.74  ? 51  ASP G CG  1 
ATOM   19409 O OD1 . ASP G 1 51  ? 13.081  1.857   70.208  1.00 47.49  ? 51  ASP G OD1 1 
ATOM   19410 O OD2 . ASP G 1 51  ? 12.896  3.053   68.361  1.00 38.58  ? 51  ASP G OD2 1 
ATOM   19411 N N   . THR G 1 52  ? 9.931   0.997   71.372  1.00 45.28  ? 52  THR G N   1 
ATOM   19412 C CA  . THR G 1 52  ? 9.607   -0.305  71.939  1.00 49.34  ? 52  THR G CA  1 
ATOM   19413 C C   . THR G 1 52  ? 10.005  -1.403  70.974  1.00 51.37  ? 52  THR G C   1 
ATOM   19414 O O   . THR G 1 52  ? 9.720   -1.326  69.773  1.00 47.29  ? 52  THR G O   1 
ATOM   19415 C CB  . THR G 1 52  ? 8.119   -0.450  72.266  1.00 52.11  ? 52  THR G CB  1 
ATOM   19416 O OG1 . THR G 1 52  ? 7.339   0.228   71.266  1.00 56.49  ? 52  THR G OG1 1 
ATOM   19417 C CG2 . THR G 1 52  ? 7.810   0.081   73.671  1.00 55.00  ? 52  THR G CG2 1 
ATOM   19418 N N   . VAL G 1 53  ? 10.617  -2.441  71.530  1.00 43.90  ? 53  VAL G N   1 
ATOM   19419 C CA  . VAL G 1 53  ? 11.190  -3.545  70.780  1.00 42.49  ? 53  VAL G CA  1 
ATOM   19420 C C   . VAL G 1 53  ? 10.378  -4.812  71.009  1.00 43.03  ? 53  VAL G C   1 
ATOM   19421 O O   . VAL G 1 53  ? 9.861   -5.049  72.108  1.00 39.08  ? 53  VAL G O   1 
ATOM   19422 C CB  . VAL G 1 53  ? 12.659  -3.755  71.190  1.00 40.23  ? 53  VAL G CB  1 
ATOM   19423 C CG1 . VAL G 1 53  ? 13.364  -4.598  70.184  1.00 40.29  ? 53  VAL G CG1 1 
ATOM   19424 C CG2 . VAL G 1 53  ? 13.353  -2.417  71.256  1.00 44.49  ? 53  VAL G CG2 1 
ATOM   19425 N N   . ASP G 1 54  ? 10.271  -5.622  69.957  1.00 40.96  ? 54  ASP G N   1 
ATOM   19426 C CA  . ASP G 1 54  ? 9.785   -6.992  70.018  1.00 33.61  ? 54  ASP G CA  1 
ATOM   19427 C C   . ASP G 1 54  ? 10.395  -7.709  71.217  1.00 38.74  ? 54  ASP G C   1 
ATOM   19428 O O   . ASP G 1 54  ? 11.625  -7.803  71.331  1.00 35.73  ? 54  ASP G O   1 
ATOM   19429 C CB  . ASP G 1 54  ? 10.135  -7.706  68.711  1.00 38.74  ? 54  ASP G CB  1 
ATOM   19430 C CG  . ASP G 1 54  ? 9.385   -9.005  68.525  1.00 37.47  ? 54  ASP G CG  1 
ATOM   19431 O OD1 . ASP G 1 54  ? 9.342   -9.813  69.475  1.00 39.25  ? 54  ASP G OD1 1 
ATOM   19432 O OD2 . ASP G 1 54  ? 8.814   -9.195  67.426  1.00 33.06  ? 54  ASP G OD2 1 
ATOM   19433 N N   . PRO G 1 55  ? 9.573   -8.209  72.144  1.00 35.95  ? 55  PRO G N   1 
ATOM   19434 C CA  . PRO G 1 55  ? 10.123  -8.919  73.298  1.00 40.14  ? 55  PRO G CA  1 
ATOM   19435 C C   . PRO G 1 55  ? 11.038  -10.081 72.915  1.00 37.56  ? 55  PRO G C   1 
ATOM   19436 O O   . PRO G 1 55  ? 11.845  -10.522 73.739  1.00 35.50  ? 55  PRO G O   1 
ATOM   19437 C CB  . PRO G 1 55  ? 8.866   -9.395  74.044  1.00 42.16  ? 55  PRO G CB  1 
ATOM   19438 C CG  . PRO G 1 55  ? 7.735   -9.238  73.066  1.00 37.90  ? 55  PRO G CG  1 
ATOM   19439 C CD  . PRO G 1 55  ? 8.111   -8.084  72.225  1.00 36.10  ? 55  PRO G CD  1 
ATOM   19440 N N   . ASP G 1 56  ? 10.964  -10.569 71.671  1.00 33.49  ? 56  ASP G N   1 
ATOM   19441 C CA  . ASP G 1 56  ? 11.862  -11.645 71.263  1.00 35.82  ? 56  ASP G CA  1 
ATOM   19442 C C   . ASP G 1 56  ? 13.161  -11.149 70.658  1.00 34.36  ? 56  ASP G C   1 
ATOM   19443 O O   . ASP G 1 56  ? 14.119  -11.927 70.583  1.00 31.64  ? 56  ASP G O   1 
ATOM   19444 C CB  . ASP G 1 56  ? 11.176  -12.574 70.256  1.00 40.87  ? 56  ASP G CB  1 
ATOM   19445 C CG  . ASP G 1 56  ? 10.321  -13.611 70.940  1.00 38.52  ? 56  ASP G CG  1 
ATOM   19446 O OD1 . ASP G 1 56  ? 9.904   -13.330 72.080  1.00 43.54  ? 56  ASP G OD1 1 
ATOM   19447 O OD2 . ASP G 1 56  ? 10.089  -14.692 70.370  1.00 32.26  ? 56  ASP G OD2 1 
ATOM   19448 N N   . PHE G 1 57  ? 13.209  -9.882  70.224  1.00 31.72  ? 57  PHE G N   1 
ATOM   19449 C CA  . PHE G 1 57  ? 14.356  -9.356  69.483  1.00 32.08  ? 57  PHE G CA  1 
ATOM   19450 C C   . PHE G 1 57  ? 15.682  -9.550  70.203  1.00 27.40  ? 57  PHE G C   1 
ATOM   19451 O O   . PHE G 1 57  ? 16.616  -10.097 69.589  1.00 25.59  ? 57  PHE G O   1 
ATOM   19452 C CB  . PHE G 1 57  ? 14.089  -7.876  69.156  1.00 35.03  ? 57  PHE G CB  1 
ATOM   19453 C CG  . PHE G 1 57  ? 14.982  -7.310  68.089  1.00 32.58  ? 57  PHE G CG  1 
ATOM   19454 C CD1 . PHE G 1 57  ? 14.887  -7.751  66.786  1.00 33.31  ? 57  PHE G CD1 1 
ATOM   19455 C CD2 . PHE G 1 57  ? 15.885  -6.302  68.384  1.00 33.31  ? 57  PHE G CD2 1 
ATOM   19456 C CE1 . PHE G 1 57  ? 15.699  -7.230  65.796  1.00 31.53  ? 57  PHE G CE1 1 
ATOM   19457 C CE2 . PHE G 1 57  ? 16.702  -5.772  67.398  1.00 30.87  ? 57  PHE G CE2 1 
ATOM   19458 C CZ  . PHE G 1 57  ? 16.602  -6.237  66.100  1.00 31.63  ? 57  PHE G CZ  1 
ATOM   19459 N N   . PRO G 1 58  ? 15.840  -9.156  71.474  1.00 32.44  ? 58  PRO G N   1 
ATOM   19460 C CA  . PRO G 1 58  ? 17.159  -9.327  72.120  1.00 30.69  ? 58  PRO G CA  1 
ATOM   19461 C C   . PRO G 1 58  ? 17.667  -10.760 72.118  1.00 27.99  ? 58  PRO G C   1 
ATOM   19462 O O   . PRO G 1 58  ? 18.863  -10.972 71.907  1.00 29.67  ? 58  PRO G O   1 
ATOM   19463 C CB  . PRO G 1 58  ? 16.920  -8.805  73.544  1.00 30.79  ? 58  PRO G CB  1 
ATOM   19464 C CG  . PRO G 1 58  ? 15.768  -7.854  73.403  1.00 32.87  ? 58  PRO G CG  1 
ATOM   19465 C CD  . PRO G 1 58  ? 14.883  -8.459  72.358  1.00 32.41  ? 58  PRO G CD  1 
ATOM   19466 N N   . GLY G 1 59  ? 16.799  -11.753 72.331  1.00 30.95  ? 59  GLY G N   1 
ATOM   19467 C CA  . GLY G 1 59  ? 17.263  -13.130 72.302  1.00 26.03  ? 59  GLY G CA  1 
ATOM   19468 C C   . GLY G 1 59  ? 17.662  -13.587 70.907  1.00 28.82  ? 59  GLY G C   1 
ATOM   19469 O O   . GLY G 1 59  ? 18.633  -14.336 70.737  1.00 32.51  ? 59  GLY G O   1 
ATOM   19470 N N   . TYR G 1 60  ? 16.918  -13.149 69.892  1.00 26.16  ? 60  TYR G N   1 
ATOM   19471 C CA  . TYR G 1 60  ? 17.258  -13.494 68.519  1.00 28.00  ? 60  TYR G CA  1 
ATOM   19472 C C   . TYR G 1 60  ? 18.638  -12.962 68.142  1.00 26.09  ? 60  TYR G C   1 
ATOM   19473 O O   . TYR G 1 60  ? 19.431  -13.661 67.499  1.00 24.78  ? 60  TYR G O   1 
ATOM   19474 C CB  . TYR G 1 60  ? 16.173  -12.958 67.592  1.00 21.82  ? 60  TYR G CB  1 
ATOM   19475 C CG  . TYR G 1 60  ? 16.636  -12.679 66.178  1.00 22.69  ? 60  TYR G CG  1 
ATOM   19476 C CD1 . TYR G 1 60  ? 17.013  -13.713 65.347  1.00 23.90  ? 60  TYR G CD1 1 
ATOM   19477 C CD2 . TYR G 1 60  ? 16.656  -11.387 65.665  1.00 24.27  ? 60  TYR G CD2 1 
ATOM   19478 C CE1 . TYR G 1 60  ? 17.408  -13.490 64.058  1.00 30.51  ? 60  TYR G CE1 1 
ATOM   19479 C CE2 . TYR G 1 60  ? 17.076  -11.147 64.362  1.00 23.04  ? 60  TYR G CE2 1 
ATOM   19480 C CZ  . TYR G 1 60  ? 17.440  -12.212 63.565  1.00 25.97  ? 60  TYR G CZ  1 
ATOM   19481 O OH  . TYR G 1 60  ? 17.858  -12.036 62.271  1.00 27.14  ? 60  TYR G OH  1 
ATOM   19482 N N   . VAL G 1 61  ? 18.955  -11.741 68.570  1.00 27.74  ? 61  VAL G N   1 
ATOM   19483 C CA  . VAL G 1 61  ? 20.257  -11.147 68.273  1.00 28.70  ? 61  VAL G CA  1 
ATOM   19484 C C   . VAL G 1 61  ? 21.363  -11.873 69.027  1.00 29.03  ? 61  VAL G C   1 
ATOM   19485 O O   . VAL G 1 61  ? 22.459  -12.094 68.494  1.00 30.64  ? 61  VAL G O   1 
ATOM   19486 C CB  . VAL G 1 61  ? 20.228  -9.634  68.596  1.00 29.63  ? 61  VAL G CB  1 
ATOM   19487 C CG1 . VAL G 1 61  ? 21.620  -9.060  68.723  1.00 23.52  ? 61  VAL G CG1 1 
ATOM   19488 C CG2 . VAL G 1 61  ? 19.440  -8.868  67.528  1.00 26.24  ? 61  VAL G CG2 1 
ATOM   19489 N N   . ALA G 1 62  ? 21.106  -12.256 70.276  1.00 26.15  ? 62  ALA G N   1 
ATOM   19490 C CA  . ALA G 1 62  ? 22.113  -13.014 71.005  1.00 27.92  ? 62  ALA G CA  1 
ATOM   19491 C C   . ALA G 1 62  ? 22.321  -14.401 70.391  1.00 34.20  ? 62  ALA G C   1 
ATOM   19492 O O   . ALA G 1 62  ? 23.454  -14.891 70.338  1.00 33.41  ? 62  ALA G O   1 
ATOM   19493 C CB  . ALA G 1 62  ? 21.723  -13.121 72.470  1.00 30.61  ? 62  ALA G CB  1 
ATOM   19494 N N   . ASP G 1 63  ? 21.242  -15.053 69.932  1.00 31.88  ? 63  ASP G N   1 
ATOM   19495 C CA  . ASP G 1 63  ? 21.384  -16.323 69.215  1.00 32.89  ? 63  ASP G CA  1 
ATOM   19496 C C   . ASP G 1 63  ? 22.295  -16.195 68.011  1.00 32.37  ? 63  ASP G C   1 
ATOM   19497 O O   . ASP G 1 63  ? 23.101  -17.090 67.733  1.00 30.90  ? 63  ASP G O   1 
ATOM   19498 C CB  . ASP G 1 63  ? 20.032  -16.827 68.708  1.00 31.10  ? 63  ASP G CB  1 
ATOM   19499 C CG  . ASP G 1 63  ? 19.089  -17.186 69.813  1.00 30.31  ? 63  ASP G CG  1 
ATOM   19500 O OD1 . ASP G 1 63  ? 19.431  -16.954 70.986  1.00 37.80  ? 63  ASP G OD1 1 
ATOM   19501 O OD2 . ASP G 1 63  ? 18.008  -17.716 69.492  1.00 30.11  ? 63  ASP G OD2 1 
ATOM   19502 N N   . THR G 1 64  ? 22.116  -15.127 67.229  1.00 31.07  ? 64  THR G N   1 
ATOM   19503 C CA  . THR G 1 64  ? 22.849  -14.986 65.979  1.00 29.15  ? 64  THR G CA  1 
ATOM   19504 C C   . THR G 1 64  ? 24.260  -14.452 66.196  1.00 32.96  ? 64  THR G C   1 
ATOM   19505 O O   . THR G 1 64  ? 25.162  -14.769 65.413  1.00 34.39  ? 64  THR G O   1 
ATOM   19506 C CB  . THR G 1 64  ? 22.090  -14.064 65.029  1.00 27.12  ? 64  THR G CB  1 
ATOM   19507 O OG1 . THR G 1 64  ? 20.685  -14.286 65.179  1.00 27.77  ? 64  THR G OG1 1 
ATOM   19508 C CG2 . THR G 1 64  ? 22.499  -14.338 63.584  1.00 31.46  ? 64  THR G CG2 1 
ATOM   19509 N N   . LEU G 1 65  ? 24.479  -13.655 67.245  1.00 32.04  ? 65  LEU G N   1 
ATOM   19510 C CA  . LEU G 1 65  ? 25.824  -13.172 67.536  1.00 30.78  ? 65  LEU G CA  1 
ATOM   19511 C C   . LEU G 1 65  ? 26.651  -14.190 68.302  1.00 34.76  ? 65  LEU G C   1 
ATOM   19512 O O   . LEU G 1 65  ? 27.882  -14.146 68.221  1.00 38.46  ? 65  LEU G O   1 
ATOM   19513 C CB  . LEU G 1 65  ? 25.757  -11.865 68.326  1.00 29.92  ? 65  LEU G CB  1 
ATOM   19514 C CG  . LEU G 1 65  ? 25.346  -10.635 67.502  1.00 30.69  ? 65  LEU G CG  1 
ATOM   19515 C CD1 . LEU G 1 65  ? 25.409  -9.362  68.344  1.00 30.42  ? 65  LEU G CD1 1 
ATOM   19516 C CD2 . LEU G 1 65  ? 26.197  -10.494 66.240  1.00 29.99  ? 65  LEU G CD2 1 
ATOM   19517 N N   . GLY G 1 66  ? 26.005  -15.111 69.020  1.00 39.23  ? 66  GLY G N   1 
ATOM   19518 C CA  . GLY G 1 66  ? 26.720  -16.048 69.864  1.00 36.16  ? 66  GLY G CA  1 
ATOM   19519 C C   . GLY G 1 66  ? 27.059  -15.498 71.227  1.00 34.41  ? 66  GLY G C   1 
ATOM   19520 O O   . GLY G 1 66  ? 28.040  -15.932 71.840  1.00 34.99  ? 66  GLY G O   1 
ATOM   19521 N N   . ILE G 1 67  ? 26.272  -14.549 71.722  1.00 34.36  ? 67  ILE G N   1 
ATOM   19522 C CA  . ILE G 1 67  ? 26.550  -13.878 72.982  1.00 33.68  ? 67  ILE G CA  1 
ATOM   19523 C C   . ILE G 1 67  ? 25.472  -14.262 73.988  1.00 37.74  ? 67  ILE G C   1 
ATOM   19524 O O   . ILE G 1 67  ? 24.404  -14.768 73.636  1.00 34.95  ? 67  ILE G O   1 
ATOM   19525 C CB  . ILE G 1 67  ? 26.648  -12.339 72.823  1.00 36.26  ? 67  ILE G CB  1 
ATOM   19526 C CG1 . ILE G 1 67  ? 25.342  -11.741 72.320  1.00 32.99  ? 67  ILE G CG1 1 
ATOM   19527 C CG2 . ILE G 1 67  ? 27.795  -11.936 71.922  1.00 34.91  ? 67  ILE G CG2 1 
ATOM   19528 C CD1 . ILE G 1 67  ? 24.680  -10.853 73.351  1.00 40.84  ? 67  ILE G CD1 1 
ATOM   19529 N N   . ASP G 1 68  ? 25.767  -14.010 75.260  1.00 38.17  ? 68  ASP G N   1 
ATOM   19530 C CA  . ASP G 1 68  ? 24.893  -14.389 76.371  1.00 42.51  ? 68  ASP G CA  1 
ATOM   19531 C C   . ASP G 1 68  ? 23.766  -13.367 76.483  1.00 39.33  ? 68  ASP G C   1 
ATOM   19532 O O   . ASP G 1 68  ? 23.942  -12.293 77.061  1.00 38.83  ? 68  ASP G O   1 
ATOM   19533 C CB  . ASP G 1 68  ? 25.705  -14.482 77.661  1.00 39.49  ? 68  ASP G CB  1 
ATOM   19534 C CG  . ASP G 1 68  ? 24.865  -14.848 78.871  1.00 45.18  ? 68  ASP G CG  1 
ATOM   19535 O OD1 . ASP G 1 68  ? 23.752  -15.400 78.705  1.00 45.40  ? 68  ASP G OD1 1 
ATOM   19536 O OD2 . ASP G 1 68  ? 25.334  -14.599 80.003  1.00 49.26  ? 68  ASP G OD2 1 
ATOM   19537 N N   . GLY G 1 69  ? 22.588  -13.718 75.957  1.00 37.89  ? 69  GLY G N   1 
ATOM   19538 C CA  . GLY G 1 69  ? 21.488  -12.767 75.910  1.00 37.63  ? 69  GLY G CA  1 
ATOM   19539 C C   . GLY G 1 69  ? 20.922  -12.397 77.268  1.00 47.34  ? 69  GLY G C   1 
ATOM   19540 O O   . GLY G 1 69  ? 20.354  -11.306 77.432  1.00 41.71  ? 69  GLY G O   1 
ATOM   19541 N N   . THR G 1 70  ? 21.064  -13.284 78.262  1.00 46.60  ? 70  THR G N   1 
ATOM   19542 C CA  . THR G 1 70  ? 20.581  -12.939 79.596  1.00 49.85  ? 70  THR G CA  1 
ATOM   19543 C C   . THR G 1 70  ? 21.413  -11.828 80.225  1.00 45.53  ? 70  THR G C   1 
ATOM   19544 O O   . THR G 1 70  ? 20.931  -11.155 81.147  1.00 45.59  ? 70  THR G O   1 
ATOM   19545 C CB  . THR G 1 70  ? 20.553  -14.168 80.525  1.00 46.45  ? 70  THR G CB  1 
ATOM   19546 O OG1 . THR G 1 70  ? 21.880  -14.494 80.952  1.00 45.62  ? 70  THR G OG1 1 
ATOM   19547 C CG2 . THR G 1 70  ? 19.920  -15.379 79.831  1.00 40.34  ? 70  THR G CG2 1 
ATOM   19548 N N   . SER G 1 71  ? 22.633  -11.599 79.728  1.00 42.14  ? 71  SER G N   1 
ATOM   19549 C CA  . SER G 1 71  ? 23.476  -10.526 80.242  1.00 42.10  ? 71  SER G CA  1 
ATOM   19550 C C   . SER G 1 71  ? 23.228  -9.175  79.571  1.00 44.83  ? 71  SER G C   1 
ATOM   19551 O O   . SER G 1 71  ? 23.650  -8.150  80.119  1.00 48.24  ? 71  SER G O   1 
ATOM   19552 C CB  . SER G 1 71  ? 24.959  -10.894 80.106  1.00 39.55  ? 71  SER G CB  1 
ATOM   19553 O OG  . SER G 1 71  ? 25.381  -10.870 78.750  1.00 34.72  ? 71  SER G OG  1 
ATOM   19554 N N   . VAL G 1 72  ? 22.564  -9.126  78.415  1.00 44.95  ? 72  VAL G N   1 
ATOM   19555 C CA  . VAL G 1 72  ? 22.276  -7.838  77.781  1.00 39.92  ? 72  VAL G CA  1 
ATOM   19556 C C   . VAL G 1 72  ? 20.998  -7.271  78.383  1.00 41.73  ? 72  VAL G C   1 
ATOM   19557 O O   . VAL G 1 72  ? 19.993  -7.980  78.501  1.00 36.91  ? 72  VAL G O   1 
ATOM   19558 C CB  . VAL G 1 72  ? 22.158  -7.978  76.251  1.00 46.08  ? 72  VAL G CB  1 
ATOM   19559 C CG1 . VAL G 1 72  ? 21.759  -6.632  75.618  1.00 36.89  ? 72  VAL G CG1 1 
ATOM   19560 C CG2 . VAL G 1 72  ? 23.466  -8.479  75.648  1.00 37.45  ? 72  VAL G CG2 1 
ATOM   19561 N N   . HIS G 1 73  ? 21.037  -5.993  78.773  1.00 36.36  ? 73  HIS G N   1 
ATOM   19562 C CA  . HIS G 1 73  ? 19.919  -5.315  79.419  1.00 39.75  ? 73  HIS G CA  1 
ATOM   19563 C C   . HIS G 1 73  ? 19.392  -4.197  78.524  1.00 39.41  ? 73  HIS G C   1 
ATOM   19564 O O   . HIS G 1 73  ? 20.167  -3.479  77.882  1.00 37.27  ? 73  HIS G O   1 
ATOM   19565 C CB  . HIS G 1 73  ? 20.329  -4.728  80.779  1.00 38.51  ? 73  HIS G CB  1 
ATOM   19566 C CG  . HIS G 1 73  ? 20.909  -5.727  81.739  1.00 49.08  ? 73  HIS G CG  1 
ATOM   19567 N ND1 . HIS G 1 73  ? 22.240  -6.098  81.724  1.00 47.96  ? 73  HIS G ND1 1 
ATOM   19568 C CD2 . HIS G 1 73  ? 20.342  -6.407  82.765  1.00 48.32  ? 73  HIS G CD2 1 
ATOM   19569 C CE1 . HIS G 1 73  ? 22.462  -6.973  82.690  1.00 46.39  ? 73  HIS G CE1 1 
ATOM   19570 N NE2 . HIS G 1 73  ? 21.329  -7.173  83.340  1.00 49.79  ? 73  HIS G NE2 1 
ATOM   19571 N N   . VAL G 1 74  ? 18.075  -4.024  78.515  1.00 37.00  ? 74  VAL G N   1 
ATOM   19572 C CA  . VAL G 1 74  ? 17.402  -3.064  77.645  1.00 32.67  ? 74  VAL G CA  1 
ATOM   19573 C C   . VAL G 1 74  ? 16.657  -2.081  78.541  1.00 38.96  ? 74  VAL G C   1 
ATOM   19574 O O   . VAL G 1 74  ? 15.664  -2.454  79.179  1.00 43.00  ? 74  VAL G O   1 
ATOM   19575 C CB  . VAL G 1 74  ? 16.430  -3.755  76.675  1.00 32.51  ? 74  VAL G CB  1 
ATOM   19576 C CG1 . VAL G 1 74  ? 15.707  -2.727  75.837  1.00 40.06  ? 74  VAL G CG1 1 
ATOM   19577 C CG2 . VAL G 1 74  ? 17.147  -4.773  75.788  1.00 29.98  ? 74  VAL G CG2 1 
ATOM   19578 N N   . GLU G 1 75  ? 17.110  -0.824  78.583  1.00 35.83  ? 75  GLU G N   1 
ATOM   19579 C CA  . GLU G 1 75  ? 16.472  0.207   79.400  1.00 36.12  ? 75  GLU G CA  1 
ATOM   19580 C C   . GLU G 1 75  ? 15.548  1.044   78.518  1.00 34.66  ? 75  GLU G C   1 
ATOM   19581 O O   . GLU G 1 75  ? 16.009  1.772   77.631  1.00 36.96  ? 75  GLU G O   1 
ATOM   19582 C CB  . GLU G 1 75  ? 17.508  1.097   80.081  1.00 36.07  ? 75  GLU G CB  1 
ATOM   19583 C CG  . GLU G 1 75  ? 18.227  0.521   81.312  1.00 38.34  ? 75  GLU G CG  1 
ATOM   19584 C CD  . GLU G 1 75  ? 17.303  0.087   82.442  1.00 39.47  ? 75  GLU G CD  1 
ATOM   19585 O OE1 . GLU G 1 75  ? 16.215  0.678   82.592  1.00 42.79  ? 75  GLU G OE1 1 
ATOM   19586 O OE2 . GLU G 1 75  ? 17.705  -0.804  83.231  1.00 37.66  ? 75  GLU G OE2 1 
ATOM   19587 N N   . ARG G 1 76  ? 14.252  0.959   78.774  1.00 33.81  ? 76  ARG G N   1 
ATOM   19588 C CA  . ARG G 1 76  ? 13.264  1.685   77.991  1.00 40.81  ? 76  ARG G CA  1 
ATOM   19589 C C   . ARG G 1 76  ? 12.989  3.036   78.636  1.00 42.66  ? 76  ARG G C   1 
ATOM   19590 O O   . ARG G 1 76  ? 12.735  3.110   79.840  1.00 50.59  ? 76  ARG G O   1 
ATOM   19591 C CB  . ARG G 1 76  ? 11.969  0.877   77.866  1.00 46.97  ? 76  ARG G CB  1 
ATOM   19592 C CG  . ARG G 1 76  ? 12.116  -0.455  77.109  1.00 41.32  ? 76  ARG G CG  1 
ATOM   19593 C CD  . ARG G 1 76  ? 11.953  -1.678  78.036  1.00 50.83  ? 76  ARG G CD  1 
ATOM   19594 N NE  . ARG G 1 76  ? 12.113  -2.963  77.350  1.00 43.25  ? 76  ARG G NE  1 
ATOM   19595 C CZ  . ARG G 1 76  ? 11.213  -3.500  76.532  1.00 49.16  ? 76  ARG G CZ  1 
ATOM   19596 N NH1 . ARG G 1 76  ? 10.060  -2.897  76.271  1.00 42.95  ? 76  ARG G NH1 1 
ATOM   19597 N NH2 . ARG G 1 76  ? 11.473  -4.676  75.964  1.00 45.84  ? 76  ARG G NH2 1 
ATOM   19598 N N   . THR G 1 77  ? 13.090  4.102   77.846  1.00 41.09  ? 77  THR G N   1 
ATOM   19599 C CA  . THR G 1 77  ? 12.640  5.426   78.235  1.00 41.53  ? 77  THR G CA  1 
ATOM   19600 C C   . THR G 1 77  ? 11.427  5.786   77.394  1.00 47.61  ? 77  THR G C   1 
ATOM   19601 O O   . THR G 1 77  ? 11.215  5.235   76.315  1.00 46.80  ? 77  THR G O   1 
ATOM   19602 C CB  . THR G 1 77  ? 13.725  6.482   78.031  1.00 38.46  ? 77  THR G CB  1 
ATOM   19603 O OG1 . THR G 1 77  ? 13.829  6.779   76.632  1.00 39.39  ? 77  THR G OG1 1 
ATOM   19604 C CG2 . THR G 1 77  ? 15.052  5.976   78.544  1.00 39.30  ? 77  THR G CG2 1 
ATOM   19605 N N   . GLN G 1 78  ? 10.638  6.730   77.888  1.00 47.20  ? 78  GLN G N   1 
ATOM   19606 C CA  . GLN G 1 78  ? 9.376   7.060   77.250  1.00 52.05  ? 78  GLN G CA  1 
ATOM   19607 C C   . GLN G 1 78  ? 9.469   8.269   76.333  1.00 53.02  ? 78  GLN G C   1 
ATOM   19608 O O   . GLN G 1 78  ? 8.443   8.672   75.778  1.00 48.67  ? 78  GLN G O   1 
ATOM   19609 C CB  . GLN G 1 78  ? 8.300   7.299   78.313  1.00 63.47  ? 78  GLN G CB  1 
ATOM   19610 C CG  . GLN G 1 78  ? 7.990   6.069   79.165  1.00 62.25  ? 78  GLN G CG  1 
ATOM   19611 C CD  . GLN G 1 78  ? 8.893   5.971   80.384  1.00 67.52  ? 78  GLN G CD  1 
ATOM   19612 O OE1 . GLN G 1 78  ? 10.080  6.327   80.330  1.00 59.93  ? 78  GLN G OE1 1 
ATOM   19613 N NE2 . GLN G 1 78  ? 8.337   5.490   81.494  1.00 76.97  ? 78  GLN G NE2 1 
ATOM   19614 N N   . THR G 1 79  ? 10.657  8.848   76.163  1.00 54.90  ? 79  THR G N   1 
ATOM   19615 C CA  . THR G 1 79  ? 10.912  10.012  75.327  1.00 48.83  ? 79  THR G CA  1 
ATOM   19616 C C   . THR G 1 79  ? 12.188  9.804   74.528  1.00 46.99  ? 79  THR G C   1 
ATOM   19617 O O   . THR G 1 79  ? 13.029  8.973   74.888  1.00 41.83  ? 79  THR G O   1 
ATOM   19618 C CB  . THR G 1 79  ? 11.047  11.302  76.159  1.00 49.71  ? 79  THR G CB  1 
ATOM   19619 O OG1 . THR G 1 79  ? 11.732  11.030  77.390  1.00 50.74  ? 79  THR G OG1 1 
ATOM   19620 C CG2 . THR G 1 79  ? 9.681   11.916  76.453  1.00 53.98  ? 79  THR G CG2 1 
ATOM   19621 N N   . PRO G 1 80  ? 12.369  10.549  73.435  1.00 46.18  ? 80  PRO G N   1 
ATOM   19622 C CA  . PRO G 1 80  ? 13.657  10.514  72.729  1.00 43.17  ? 80  PRO G CA  1 
ATOM   19623 C C   . PRO G 1 80  ? 14.807  10.921  73.641  1.00 40.18  ? 80  PRO G C   1 
ATOM   19624 O O   . PRO G 1 80  ? 14.629  11.587  74.662  1.00 41.35  ? 80  PRO G O   1 
ATOM   19625 C CB  . PRO G 1 80  ? 13.471  11.513  71.576  1.00 43.17  ? 80  PRO G CB  1 
ATOM   19626 C CG  . PRO G 1 80  ? 12.159  12.226  71.840  1.00 45.75  ? 80  PRO G CG  1 
ATOM   19627 C CD  . PRO G 1 80  ? 11.344  11.311  72.698  1.00 45.14  ? 80  PRO G CD  1 
ATOM   19628 N N   . LEU G 1 81  ? 16.012  10.501  73.262  1.00 34.89  ? 81  LEU G N   1 
ATOM   19629 C CA  . LEU G 1 81  ? 17.172  10.665  74.131  1.00 35.48  ? 81  LEU G CA  1 
ATOM   19630 C C   . LEU G 1 81  ? 17.760  12.054  73.914  1.00 37.51  ? 81  LEU G C   1 
ATOM   19631 O O   . LEU G 1 81  ? 18.772  12.247  73.233  1.00 41.14  ? 81  LEU G O   1 
ATOM   19632 C CB  . LEU G 1 81  ? 18.188  9.565   73.873  1.00 38.04  ? 81  LEU G CB  1 
ATOM   19633 C CG  . LEU G 1 81  ? 17.702  8.216   74.383  1.00 35.93  ? 81  LEU G CG  1 
ATOM   19634 C CD1 . LEU G 1 81  ? 18.800  7.206   74.238  1.00 31.46  ? 81  LEU G CD1 1 
ATOM   19635 C CD2 . LEU G 1 81  ? 17.249  8.342   75.816  1.00 34.29  ? 81  LEU G CD2 1 
ATOM   19636 N N   . SER G 1 82  ? 17.110  13.033  74.527  1.00 33.09  ? 82  SER G N   1 
ATOM   19637 C CA  . SER G 1 82  ? 17.479  14.435  74.434  1.00 36.30  ? 82  SER G CA  1 
ATOM   19638 C C   . SER G 1 82  ? 18.553  14.776  75.458  1.00 33.35  ? 82  SER G C   1 
ATOM   19639 O O   . SER G 1 82  ? 18.856  13.996  76.363  1.00 36.16  ? 82  SER G O   1 
ATOM   19640 C CB  . SER G 1 82  ? 16.270  15.314  74.700  1.00 32.63  ? 82  SER G CB  1 
ATOM   19641 O OG  . SER G 1 82  ? 16.027  15.279  76.092  1.00 31.72  ? 82  SER G OG  1 
ATOM   19642 N N   . GLU G 1 83  ? 19.103  15.986  75.335  1.00 30.38  ? 83  GLU G N   1 
ATOM   19643 C CA  . GLU G 1 83  ? 19.996  16.482  76.382  1.00 35.06  ? 83  GLU G CA  1 
ATOM   19644 C C   . GLU G 1 83  ? 19.282  16.519  77.723  1.00 31.55  ? 83  GLU G C   1 
ATOM   19645 O O   . GLU G 1 83  ? 19.870  16.169  78.754  1.00 34.16  ? 83  GLU G O   1 
ATOM   19646 C CB  . GLU G 1 83  ? 20.533  17.874  76.039  1.00 32.56  ? 83  GLU G CB  1 
ATOM   19647 C CG  . GLU G 1 83  ? 21.400  17.948  74.763  1.00 33.53  ? 83  GLU G CG  1 
ATOM   19648 C CD  . GLU G 1 83  ? 22.718  17.182  74.867  1.00 30.41  ? 83  GLU G CD  1 
ATOM   19649 O OE1 . GLU G 1 83  ? 22.728  15.958  74.601  1.00 31.37  ? 83  GLU G OE1 1 
ATOM   19650 O OE2 . GLU G 1 83  ? 23.752  17.804  75.206  1.00 27.60  ? 83  GLU G OE2 1 
ATOM   19651 N N   . ALA G 1 84  ? 18.006  16.919  77.724  1.00 32.26  ? 84  ALA G N   1 
ATOM   19652 C CA  . ALA G 1 84  ? 17.228  16.948  78.959  1.00 35.78  ? 84  ALA G CA  1 
ATOM   19653 C C   . ALA G 1 84  ? 17.199  15.572  79.606  1.00 31.23  ? 84  ALA G C   1 
ATOM   19654 O O   . ALA G 1 84  ? 17.626  15.399  80.757  1.00 34.02  ? 84  ALA G O   1 
ATOM   19655 C CB  . ALA G 1 84  ? 15.813  17.447  78.671  1.00 35.54  ? 84  ALA G CB  1 
ATOM   19656 N N   . VAL G 1 85  ? 16.753  14.566  78.849  1.00 31.37  ? 85  VAL G N   1 
ATOM   19657 C CA  . VAL G 1 85  ? 16.773  13.190  79.352  1.00 28.90  ? 85  VAL G CA  1 
ATOM   19658 C C   . VAL G 1 85  ? 18.161  12.814  79.849  1.00 33.15  ? 85  VAL G C   1 
ATOM   19659 O O   . VAL G 1 85  ? 18.312  12.207  80.918  1.00 31.69  ? 85  VAL G O   1 
ATOM   19660 C CB  . VAL G 1 85  ? 16.284  12.206  78.278  1.00 33.23  ? 85  VAL G CB  1 
ATOM   19661 C CG1 . VAL G 1 85  ? 16.454  10.780  78.772  1.00 32.12  ? 85  VAL G CG1 1 
ATOM   19662 C CG2 . VAL G 1 85  ? 14.834  12.468  77.931  1.00 35.25  ? 85  VAL G CG2 1 
ATOM   19663 N N   . LEU G 1 86  ? 19.207  13.180  79.097  1.00 30.50  ? 86  LEU G N   1 
ATOM   19664 C CA  . LEU G 1 86  ? 20.536  12.741  79.514  1.00 30.63  ? 86  LEU G CA  1 
ATOM   19665 C C   . LEU G 1 86  ? 20.989  13.406  80.807  1.00 32.84  ? 86  LEU G C   1 
ATOM   19666 O O   . LEU G 1 86  ? 21.897  12.890  81.465  1.00 32.60  ? 86  LEU G O   1 
ATOM   19667 C CB  . LEU G 1 86  ? 21.562  12.997  78.422  1.00 28.76  ? 86  LEU G CB  1 
ATOM   19668 C CG  . LEU G 1 86  ? 21.357  12.344  77.052  1.00 32.64  ? 86  LEU G CG  1 
ATOM   19669 C CD1 . LEU G 1 86  ? 22.680  12.406  76.266  1.00 28.64  ? 86  LEU G CD1 1 
ATOM   19670 C CD2 . LEU G 1 86  ? 20.816  10.913  77.161  1.00 27.66  ? 86  LEU G CD2 1 
ATOM   19671 N N   . GLN G 1 87  ? 20.380  14.529  81.186  1.00 31.31  ? 87  GLN G N   1 
ATOM   19672 C CA  . GLN G 1 87  ? 20.688  15.213  82.436  1.00 38.80  ? 87  GLN G CA  1 
ATOM   19673 C C   . GLN G 1 87  ? 19.666  14.932  83.527  1.00 40.86  ? 87  GLN G C   1 
ATOM   19674 O O   . GLN G 1 87  ? 19.815  15.443  84.640  1.00 42.89  ? 87  GLN G O   1 
ATOM   19675 C CB  . GLN G 1 87  ? 20.768  16.726  82.209  1.00 41.08  ? 87  GLN G CB  1 
ATOM   19676 C CG  . GLN G 1 87  ? 21.830  17.182  81.212  1.00 42.58  ? 87  GLN G CG  1 
ATOM   19677 C CD  . GLN G 1 87  ? 21.798  18.686  80.996  1.00 47.68  ? 87  GLN G CD  1 
ATOM   19678 O OE1 . GLN G 1 87  ? 20.957  19.198  80.243  1.00 47.08  ? 87  GLN G OE1 1 
ATOM   19679 N NE2 . GLN G 1 87  ? 22.690  19.406  81.678  1.00 37.65  ? 87  GLN G NE2 1 
ATOM   19680 N N   . ASP G 1 88  ? 18.637  14.146  83.230  1.00 41.36  ? 88  ASP G N   1 
ATOM   19681 C CA  . ASP G 1 88  ? 17.576  13.890  84.195  1.00 40.61  ? 88  ASP G CA  1 
ATOM   19682 C C   . ASP G 1 88  ? 18.102  13.017  85.329  1.00 42.27  ? 88  ASP G C   1 
ATOM   19683 O O   . ASP G 1 88  ? 18.647  11.934  85.073  1.00 40.98  ? 88  ASP G O   1 
ATOM   19684 C CB  . ASP G 1 88  ? 16.395  13.215  83.499  1.00 42.58  ? 88  ASP G CB  1 
ATOM   19685 C CG  . ASP G 1 88  ? 15.207  12.967  84.429  1.00 49.61  ? 88  ASP G CG  1 
ATOM   19686 O OD1 . ASP G 1 88  ? 15.377  12.445  85.552  1.00 47.33  ? 88  ASP G OD1 1 
ATOM   19687 O OD2 . ASP G 1 88  ? 14.076  13.307  84.015  1.00 56.26  ? 88  ASP G OD2 1 
ATOM   19688 N N   . PRO G 1 89  ? 17.947  13.447  86.587  1.00 46.49  ? 89  PRO G N   1 
ATOM   19689 C CA  . PRO G 1 89  ? 18.420  12.632  87.728  1.00 47.02  ? 89  PRO G CA  1 
ATOM   19690 C C   . PRO G 1 89  ? 17.897  11.203  87.739  1.00 44.49  ? 89  PRO G C   1 
ATOM   19691 O O   . PRO G 1 89  ? 18.632  10.278  88.105  1.00 41.98  ? 89  PRO G O   1 
ATOM   19692 C CB  . PRO G 1 89  ? 17.906  13.420  88.944  1.00 40.19  ? 89  PRO G CB  1 
ATOM   19693 C CG  . PRO G 1 89  ? 17.771  14.833  88.451  1.00 41.00  ? 89  PRO G CG  1 
ATOM   19694 C CD  . PRO G 1 89  ? 17.371  14.736  87.013  1.00 43.35  ? 89  PRO G CD  1 
ATOM   19695 N N   . GLU G 1 90  ? 16.629  11.005  87.374  1.00 44.83  ? 90  GLU G N   1 
ATOM   19696 C CA  . GLU G 1 90  ? 16.058  9.665   87.384  1.00 46.11  ? 90  GLU G CA  1 
ATOM   19697 C C   . GLU G 1 90  ? 16.671  8.802   86.289  1.00 45.29  ? 90  GLU G C   1 
ATOM   19698 O O   . GLU G 1 90  ? 16.886  7.598   86.484  1.00 41.88  ? 90  GLU G O   1 
ATOM   19699 C CB  . GLU G 1 90  ? 14.537  9.749   87.231  1.00 51.20  ? 90  GLU G CB  1 
ATOM   19700 C CG  . GLU G 1 90  ? 13.841  10.563  88.330  1.00 60.07  ? 90  GLU G CG  1 
ATOM   19701 C CD  . GLU G 1 90  ? 12.467  10.004  88.703  1.00 71.46  ? 90  GLU G CD  1 
ATOM   19702 O OE1 . GLU G 1 90  ? 11.862  10.492  89.690  1.00 73.72  ? 90  GLU G OE1 1 
ATOM   19703 O OE2 . GLU G 1 90  ? 11.993  9.076   88.008  1.00 71.74  ? 90  GLU G OE2 1 
ATOM   19704 N N   . PHE G 1 91  ? 16.948  9.396   85.126  1.00 40.39  ? 91  PHE G N   1 
ATOM   19705 C CA  . PHE G 1 91  ? 17.628  8.663   84.063  1.00 36.49  ? 91  PHE G CA  1 
ATOM   19706 C C   . PHE G 1 91  ? 19.002  8.198   84.523  1.00 35.51  ? 91  PHE G C   1 
ATOM   19707 O O   . PHE G 1 91  ? 19.345  7.016   84.413  1.00 35.81  ? 91  PHE G O   1 
ATOM   19708 C CB  . PHE G 1 91  ? 17.753  9.545   82.823  1.00 34.99  ? 91  PHE G CB  1 
ATOM   19709 C CG  . PHE G 1 91  ? 18.471  8.886   81.685  1.00 35.56  ? 91  PHE G CG  1 
ATOM   19710 C CD1 . PHE G 1 91  ? 17.879  7.843   80.987  1.00 32.39  ? 91  PHE G CD1 1 
ATOM   19711 C CD2 . PHE G 1 91  ? 19.748  9.292   81.329  1.00 32.21  ? 91  PHE G CD2 1 
ATOM   19712 C CE1 . PHE G 1 91  ? 18.542  7.227   79.941  1.00 32.50  ? 91  PHE G CE1 1 
ATOM   19713 C CE2 . PHE G 1 91  ? 20.421  8.684   80.277  1.00 36.68  ? 91  PHE G CE2 1 
ATOM   19714 C CZ  . PHE G 1 91  ? 19.812  7.648   79.582  1.00 36.31  ? 91  PHE G CZ  1 
ATOM   19715 N N   . ILE G 1 92  ? 19.803  9.127   85.039  1.00 36.13  ? 92  ILE G N   1 
ATOM   19716 C CA  . ILE G 1 92  ? 21.129  8.791   85.542  1.00 38.60  ? 92  ILE G CA  1 
ATOM   19717 C C   . ILE G 1 92  ? 21.038  7.737   86.642  1.00 42.11  ? 92  ILE G C   1 
ATOM   19718 O O   . ILE G 1 92  ? 21.894  6.846   86.734  1.00 38.61  ? 92  ILE G O   1 
ATOM   19719 C CB  . ILE G 1 92  ? 21.836  10.070  86.026  1.00 40.97  ? 92  ILE G CB  1 
ATOM   19720 C CG1 . ILE G 1 92  ? 21.798  11.134  84.919  1.00 37.99  ? 92  ILE G CG1 1 
ATOM   19721 C CG2 . ILE G 1 92  ? 23.256  9.769   86.463  1.00 38.57  ? 92  ILE G CG2 1 
ATOM   19722 C CD1 . ILE G 1 92  ? 22.120  12.544  85.402  1.00 37.37  ? 92  ILE G CD1 1 
ATOM   19723 N N   . ASP G 1 93  ? 19.998  7.814   87.488  1.00 39.14  ? 93  ASP G N   1 
ATOM   19724 C CA  . ASP G 1 93  ? 19.797  6.798   88.523  1.00 41.06  ? 93  ASP G CA  1 
ATOM   19725 C C   . ASP G 1 93  ? 19.679  5.410   87.911  1.00 34.40  ? 93  ASP G C   1 
ATOM   19726 O O   . ASP G 1 93  ? 20.314  4.456   88.377  1.00 37.74  ? 93  ASP G O   1 
ATOM   19727 C CB  . ASP G 1 93  ? 18.546  7.119   89.343  1.00 42.59  ? 93  ASP G CB  1 
ATOM   19728 C CG  . ASP G 1 93  ? 18.822  8.066   90.500  1.00 51.78  ? 93  ASP G CG  1 
ATOM   19729 O OD1 . ASP G 1 93  ? 20.011  8.298   90.826  1.00 50.82  ? 93  ASP G OD1 1 
ATOM   19730 O OD2 . ASP G 1 93  ? 17.836  8.595   91.068  1.00 53.46  ? 93  ASP G OD2 1 
ATOM   19731 N N   . ARG G 1 94  ? 18.859  5.282   86.867  1.00 32.87  ? 94  ARG G N   1 
ATOM   19732 C CA  . ARG G 1 94  ? 18.649  3.989   86.218  1.00 36.11  ? 94  ARG G CA  1 
ATOM   19733 C C   . ARG G 1 94  ? 19.962  3.395   85.740  1.00 36.44  ? 94  ARG G C   1 
ATOM   19734 O O   . ARG G 1 94  ? 20.262  2.223   85.990  1.00 40.88  ? 94  ARG G O   1 
ATOM   19735 C CB  . ARG G 1 94  ? 17.705  4.146   85.032  1.00 38.08  ? 94  ARG G CB  1 
ATOM   19736 C CG  . ARG G 1 94  ? 16.286  4.471   85.389  1.00 36.56  ? 94  ARG G CG  1 
ATOM   19737 C CD  . ARG G 1 94  ? 15.370  3.751   84.427  1.00 36.13  ? 94  ARG G CD  1 
ATOM   19738 N NE  . ARG G 1 94  ? 14.658  4.700   83.586  1.00 41.59  ? 94  ARG G NE  1 
ATOM   19739 C CZ  . ARG G 1 94  ? 14.021  4.382   82.469  1.00 40.24  ? 94  ARG G CZ  1 
ATOM   19740 N NH1 . ARG G 1 94  ? 14.022  3.144   82.004  1.00 40.76  ? 94  ARG G NH1 1 
ATOM   19741 N NH2 . ARG G 1 94  ? 13.362  5.330   81.808  1.00 49.80  ? 94  ARG G NH2 1 
ATOM   19742 N N   . LEU G 1 95  ? 20.761  4.195   85.041  1.00 37.69  ? 95  LEU G N   1 
ATOM   19743 C CA  . LEU G 1 95  ? 22.025  3.684   84.544  1.00 36.23  ? 95  LEU G CA  1 
ATOM   19744 C C   . LEU G 1 95  ? 23.003  3.423   85.677  1.00 33.95  ? 95  LEU G C   1 
ATOM   19745 O O   . LEU G 1 95  ? 23.813  2.495   85.581  1.00 38.76  ? 95  LEU G O   1 
ATOM   19746 C CB  . LEU G 1 95  ? 22.608  4.653   83.513  1.00 32.32  ? 95  LEU G CB  1 
ATOM   19747 C CG  . LEU G 1 95  ? 21.683  5.020   82.350  1.00 34.16  ? 95  LEU G CG  1 
ATOM   19748 C CD1 . LEU G 1 95  ? 22.449  5.715   81.234  1.00 34.53  ? 95  LEU G CD1 1 
ATOM   19749 C CD2 . LEU G 1 95  ? 20.922  3.819   81.808  1.00 32.81  ? 95  LEU G CD2 1 
ATOM   19750 N N   . ALA G 1 96  ? 22.944  4.213   86.759  1.00 36.94  ? 96  ALA G N   1 
ATOM   19751 C CA  . ALA G 1 96  ? 23.860  3.998   87.881  1.00 39.04  ? 96  ALA G CA  1 
ATOM   19752 C C   . ALA G 1 96  ? 23.643  2.639   88.534  1.00 38.31  ? 96  ALA G C   1 
ATOM   19753 O O   . ALA G 1 96  ? 24.585  2.058   89.088  1.00 34.75  ? 96  ALA G O   1 
ATOM   19754 C CB  . ALA G 1 96  ? 23.710  5.108   88.921  1.00 39.24  ? 96  ALA G CB  1 
ATOM   19755 N N   . ALA G 1 97  ? 22.418  2.109   88.464  1.00 37.05  ? 97  ALA G N   1 
ATOM   19756 C CA  . ALA G 1 97  ? 22.170  0.774   88.998  1.00 40.32  ? 97  ALA G CA  1 
ATOM   19757 C C   . ALA G 1 97  ? 23.045  -0.270  88.319  1.00 40.99  ? 97  ALA G C   1 
ATOM   19758 O O   . ALA G 1 97  ? 23.379  -1.294  88.927  1.00 44.12  ? 97  ALA G O   1 
ATOM   19759 C CB  . ALA G 1 97  ? 20.693  0.413   88.840  1.00 42.14  ? 97  ALA G CB  1 
ATOM   19760 N N   . HIS G 1 98  ? 23.421  -0.035  87.066  1.00 40.02  ? 98  HIS G N   1 
ATOM   19761 C CA  . HIS G 1 98  ? 24.322  -0.938  86.369  1.00 42.06  ? 98  HIS G CA  1 
ATOM   19762 C C   . HIS G 1 98  ? 25.781  -0.527  86.544  1.00 42.47  ? 98  HIS G C   1 
ATOM   19763 O O   . HIS G 1 98  ? 26.643  -1.369  86.823  1.00 41.18  ? 98  HIS G O   1 
ATOM   19764 C CB  . HIS G 1 98  ? 23.987  -0.976  84.875  1.00 37.30  ? 98  HIS G CB  1 
ATOM   19765 C CG  . HIS G 1 98  ? 22.585  -1.389  84.559  1.00 37.51  ? 98  HIS G CG  1 
ATOM   19766 N ND1 . HIS G 1 98  ? 22.187  -2.711  84.514  1.00 44.22  ? 98  HIS G ND1 1 
ATOM   19767 C CD2 . HIS G 1 98  ? 21.497  -0.656  84.226  1.00 35.69  ? 98  HIS G CD2 1 
ATOM   19768 C CE1 . HIS G 1 98  ? 20.910  -2.772  84.179  1.00 40.73  ? 98  HIS G CE1 1 
ATOM   19769 N NE2 . HIS G 1 98  ? 20.468  -1.540  83.995  1.00 39.57  ? 98  HIS G NE2 1 
ATOM   19770 N N   . THR G 1 99  ? 26.081  0.759   86.351  1.00 38.98  ? 99  THR G N   1 
ATOM   19771 C CA  . THR G 1 99  ? 27.477  1.176   86.312  1.00 34.87  ? 99  THR G CA  1 
ATOM   19772 C C   . THR G 1 99  ? 28.091  1.128   87.703  1.00 38.94  ? 99  THR G C   1 
ATOM   19773 O O   . THR G 1 99  ? 29.239  0.700   87.860  1.00 43.04  ? 99  THR G O   1 
ATOM   19774 C CB  . THR G 1 99  ? 27.601  2.577   85.711  1.00 34.72  ? 99  THR G CB  1 
ATOM   19775 O OG1 . THR G 1 99  ? 27.016  3.530   86.596  1.00 37.27  ? 99  THR G OG1 1 
ATOM   19776 C CG2 . THR G 1 99  ? 26.861  2.663   84.407  1.00 30.92  ? 99  THR G CG2 1 
ATOM   19777 N N   . GLY G 1 100 ? 27.333  1.540   88.724  1.00 42.38  ? 100 GLY G N   1 
ATOM   19778 C CA  . GLY G 1 100 ? 27.760  1.486   90.116  1.00 42.62  ? 100 GLY G CA  1 
ATOM   19779 C C   . GLY G 1 100 ? 28.970  2.330   90.464  1.00 43.48  ? 100 GLY G C   1 
ATOM   19780 O O   . GLY G 1 100 ? 28.871  3.553   90.576  1.00 49.90  ? 100 GLY G O   1 
ATOM   19781 N N   . THR G 1 101 ? 30.119  1.674   90.659  1.00 48.93  ? 101 THR G N   1 
ATOM   19782 C CA  . THR G 1 101 ? 31.386  2.385   90.825  1.00 47.19  ? 101 THR G CA  1 
ATOM   19783 C C   . THR G 1 101 ? 31.721  3.198   89.587  1.00 50.09  ? 101 THR G C   1 
ATOM   19784 O O   . THR G 1 101 ? 32.405  4.230   89.670  1.00 45.01  ? 101 THR G O   1 
ATOM   19785 C CB  . THR G 1 101 ? 32.508  1.375   91.101  1.00 48.15  ? 101 THR G CB  1 
ATOM   19786 O OG1 . THR G 1 101 ? 32.415  0.904   92.451  1.00 60.69  ? 101 THR G OG1 1 
ATOM   19787 C CG2 . THR G 1 101 ? 33.883  1.989   90.884  1.00 53.55  ? 101 THR G CG2 1 
ATOM   19788 N N   . GLY G 1 102 ? 31.213  2.764   88.437  1.00 46.76  ? 102 GLY G N   1 
ATOM   19789 C CA  . GLY G 1 102 ? 31.720  3.173   87.159  1.00 43.39  ? 102 GLY G CA  1 
ATOM   19790 C C   . GLY G 1 102 ? 32.819  2.283   86.634  1.00 46.85  ? 102 GLY G C   1 
ATOM   19791 O O   . GLY G 1 102 ? 33.033  2.238   85.413  1.00 45.24  ? 102 GLY G O   1 
ATOM   19792 N N   . ALA G 1 103 ? 33.504  1.553   87.518  1.00 45.60  ? 103 ALA G N   1 
ATOM   19793 C CA  . ALA G 1 103 ? 34.635  0.731   87.107  1.00 44.57  ? 103 ALA G CA  1 
ATOM   19794 C C   . ALA G 1 103 ? 34.250  -0.195  85.961  1.00 35.75  ? 103 ALA G C   1 
ATOM   19795 O O   . ALA G 1 103 ? 33.227  -0.880  86.018  1.00 37.83  ? 103 ALA G O   1 
ATOM   19796 C CB  . ALA G 1 103 ? 35.150  -0.084  88.294  1.00 44.97  ? 103 ALA G CB  1 
ATOM   19797 N N   . GLY G 1 104 ? 35.059  -0.181  84.903  1.00 38.26  ? 104 GLY G N   1 
ATOM   19798 C CA  . GLY G 1 104 ? 34.876  -1.092  83.789  1.00 33.31  ? 104 GLY G CA  1 
ATOM   19799 C C   . GLY G 1 104 ? 33.718  -0.783  82.867  1.00 36.98  ? 104 GLY G C   1 
ATOM   19800 O O   . GLY G 1 104 ? 33.389  -1.613  82.015  1.00 43.39  ? 104 GLY G O   1 
ATOM   19801 N N   . TRP G 1 105 ? 33.081  0.371   83.007  1.00 31.80  ? 105 TRP G N   1 
ATOM   19802 C CA  . TRP G 1 105 ? 31.994  0.780   82.134  1.00 33.75  ? 105 TRP G CA  1 
ATOM   19803 C C   . TRP G 1 105 ? 32.438  1.941   81.260  1.00 34.58  ? 105 TRP G C   1 
ATOM   19804 O O   . TRP G 1 105 ? 33.419  2.632   81.549  1.00 30.95  ? 105 TRP G O   1 
ATOM   19805 C CB  . TRP G 1 105 ? 30.756  1.186   82.940  1.00 34.70  ? 105 TRP G CB  1 
ATOM   19806 C CG  . TRP G 1 105 ? 30.014  0.010   83.465  1.00 39.18  ? 105 TRP G CG  1 
ATOM   19807 C CD1 . TRP G 1 105 ? 30.305  -0.713  84.595  1.00 39.54  ? 105 TRP G CD1 1 
ATOM   19808 C CD2 . TRP G 1 105 ? 28.872  -0.616  82.869  1.00 37.10  ? 105 TRP G CD2 1 
ATOM   19809 N NE1 . TRP G 1 105 ? 29.403  -1.740  84.739  1.00 40.31  ? 105 TRP G NE1 1 
ATOM   19810 C CE2 . TRP G 1 105 ? 28.512  -1.701  83.696  1.00 38.68  ? 105 TRP G CE2 1 
ATOM   19811 C CE3 . TRP G 1 105 ? 28.115  -0.358  81.724  1.00 37.41  ? 105 TRP G CE3 1 
ATOM   19812 C CZ2 . TRP G 1 105 ? 27.427  -2.529  83.413  1.00 34.28  ? 105 TRP G CZ2 1 
ATOM   19813 C CZ3 . TRP G 1 105 ? 27.033  -1.175  81.447  1.00 41.05  ? 105 TRP G CZ3 1 
ATOM   19814 C CH2 . TRP G 1 105 ? 26.702  -2.252  82.291  1.00 39.99  ? 105 TRP G CH2 1 
ATOM   19815 N N   . SER G 1 106 ? 31.704  2.141   80.174  1.00 30.79  ? 106 SER G N   1 
ATOM   19816 C CA  . SER G 1 106 ? 31.936  3.283   79.304  1.00 28.95  ? 106 SER G CA  1 
ATOM   19817 C C   . SER G 1 106 ? 30.652  3.524   78.526  1.00 26.22  ? 106 SER G C   1 
ATOM   19818 O O   . SER G 1 106 ? 29.749  2.692   78.516  1.00 26.72  ? 106 SER G O   1 
ATOM   19819 C CB  . SER G 1 106 ? 33.148  3.062   78.383  1.00 35.35  ? 106 SER G CB  1 
ATOM   19820 O OG  . SER G 1 106 ? 32.826  2.350   77.202  1.00 36.54  ? 106 SER G OG  1 
ATOM   19821 N N   . LEU G 1 107 ? 30.568  4.688   77.903  1.00 30.86  ? 107 LEU G N   1 
ATOM   19822 C CA  . LEU G 1 107 ? 29.370  5.133   77.209  1.00 28.79  ? 107 LEU G CA  1 
ATOM   19823 C C   . LEU G 1 107 ? 29.652  5.102   75.713  1.00 31.35  ? 107 LEU G C   1 
ATOM   19824 O O   . LEU G 1 107 ? 30.705  5.572   75.271  1.00 30.61  ? 107 LEU G O   1 
ATOM   19825 C CB  . LEU G 1 107 ? 28.983  6.534   77.680  1.00 24.61  ? 107 LEU G CB  1 
ATOM   19826 C CG  . LEU G 1 107 ? 27.575  7.101   77.547  1.00 31.37  ? 107 LEU G CG  1 
ATOM   19827 C CD1 . LEU G 1 107 ? 27.391  7.570   76.169  1.00 37.11  ? 107 LEU G CD1 1 
ATOM   19828 C CD2 . LEU G 1 107 ? 26.491  6.094   77.871  1.00 30.49  ? 107 LEU G CD2 1 
ATOM   19829 N N   . PHE G 1 108 ? 28.723  4.523   74.944  1.00 30.26  ? 108 PHE G N   1 
ATOM   19830 C CA  . PHE G 1 108 ? 28.847  4.353   73.500  1.00 25.52  ? 108 PHE G CA  1 
ATOM   19831 C C   . PHE G 1 108 ? 27.703  5.148   72.894  1.00 25.35  ? 108 PHE G C   1 
ATOM   19832 O O   . PHE G 1 108 ? 26.645  4.583   72.598  1.00 27.21  ? 108 PHE G O   1 
ATOM   19833 C CB  . PHE G 1 108 ? 28.791  2.877   73.102  1.00 29.21  ? 108 PHE G CB  1 
ATOM   19834 C CG  . PHE G 1 108 ? 29.129  2.595   71.651  1.00 34.88  ? 108 PHE G CG  1 
ATOM   19835 C CD1 . PHE G 1 108 ? 30.455  2.523   71.227  1.00 35.09  ? 108 PHE G CD1 1 
ATOM   19836 C CD2 . PHE G 1 108 ? 28.122  2.346   70.721  1.00 30.79  ? 108 PHE G CD2 1 
ATOM   19837 C CE1 . PHE G 1 108 ? 30.767  2.245   69.885  1.00 35.49  ? 108 PHE G CE1 1 
ATOM   19838 C CE2 . PHE G 1 108 ? 28.428  2.058   69.385  1.00 30.06  ? 108 PHE G CE2 1 
ATOM   19839 C CZ  . PHE G 1 108 ? 29.745  2.009   68.969  1.00 31.08  ? 108 PHE G CZ  1 
ATOM   19840 N N   . PRO G 1 109 ? 27.872  6.468   72.720  1.00 24.52  ? 109 PRO G N   1 
ATOM   19841 C CA  . PRO G 1 109 ? 26.772  7.312   72.240  1.00 28.03  ? 109 PRO G CA  1 
ATOM   19842 C C   . PRO G 1 109 ? 26.822  7.546   70.744  1.00 26.87  ? 109 PRO G C   1 
ATOM   19843 O O   . PRO G 1 109 ? 27.898  7.524   70.146  1.00 30.43  ? 109 PRO G O   1 
ATOM   19844 C CB  . PRO G 1 109 ? 27.002  8.630   72.994  1.00 29.06  ? 109 PRO G CB  1 
ATOM   19845 C CG  . PRO G 1 109 ? 28.527  8.734   73.086  1.00 32.47  ? 109 PRO G CG  1 
ATOM   19846 C CD  . PRO G 1 109 ? 29.074  7.274   73.011  1.00 32.97  ? 109 PRO G CD  1 
ATOM   19847 N N   . CYS G 1 110 ? 25.669  7.806   70.143  1.00 26.76  ? 110 CYS G N   1 
ATOM   19848 C CA  . CYS G 1 110 ? 25.620  8.163   68.730  1.00 26.18  ? 110 CYS G CA  1 
ATOM   19849 C C   . CYS G 1 110 ? 26.225  9.543   68.467  1.00 24.09  ? 110 CYS G C   1 
ATOM   19850 O O   . CYS G 1 110 ? 26.885  9.749   67.449  1.00 26.39  ? 110 CYS G O   1 
ATOM   19851 C CB  . CYS G 1 110 ? 24.177  8.103   68.238  1.00 30.89  ? 110 CYS G CB  1 
ATOM   19852 S SG  . CYS G 1 110 ? 23.963  8.556   66.491  1.00 31.08  ? 110 CYS G SG  1 
ATOM   19853 N N   . VAL G 1 111 ? 25.999  10.501  69.358  1.00 25.66  ? 111 VAL G N   1 
ATOM   19854 C CA  . VAL G 1 111 ? 26.517  11.860  69.225  1.00 27.97  ? 111 VAL G CA  1 
ATOM   19855 C C   . VAL G 1 111 ? 27.195  12.264  70.528  1.00 28.19  ? 111 VAL G C   1 
ATOM   19856 O O   . VAL G 1 111 ? 26.582  12.195  71.600  1.00 25.03  ? 111 VAL G O   1 
ATOM   19857 C CB  . VAL G 1 111 ? 25.406  12.866  68.874  1.00 28.95  ? 111 VAL G CB  1 
ATOM   19858 C CG1 . VAL G 1 111 ? 26.012  14.239  68.556  1.00 29.63  ? 111 VAL G CG1 1 
ATOM   19859 C CG2 . VAL G 1 111 ? 24.571  12.349  67.697  1.00 31.34  ? 111 VAL G CG2 1 
ATOM   19860 N N   . SER G 1 112 ? 28.446  12.721  70.433  1.00 28.14  ? 112 SER G N   1 
ATOM   19861 C CA  . SER G 1 112 ? 29.214  13.139  71.613  1.00 28.30  ? 112 SER G CA  1 
ATOM   19862 C C   . SER G 1 112 ? 28.837  14.567  72.034  1.00 30.37  ? 112 SER G C   1 
ATOM   19863 O O   . SER G 1 112 ? 29.653  15.494  72.016  1.00 24.46  ? 112 SER G O   1 
ATOM   19864 C CB  . SER G 1 112 ? 30.704  13.016  71.342  1.00 27.24  ? 112 SER G CB  1 
ATOM   19865 O OG  . SER G 1 112 ? 31.136  11.675  71.533  1.00 28.96  ? 112 SER G OG  1 
ATOM   19866 N N   . THR G 1 113 ? 27.577  14.712  72.468  1.00 20.73  ? 113 THR G N   1 
ATOM   19867 C CA  . THR G 1 113 ? 27.032  15.979  72.931  1.00 25.26  ? 113 THR G CA  1 
ATOM   19868 C C   . THR G 1 113 ? 27.637  16.387  74.272  1.00 25.97  ? 113 THR G C   1 
ATOM   19869 O O   . THR G 1 113 ? 28.350  15.623  74.919  1.00 25.14  ? 113 THR G O   1 
ATOM   19870 C CB  . THR G 1 113 ? 25.525  15.874  73.109  1.00 27.19  ? 113 THR G CB  1 
ATOM   19871 O OG1 . THR G 1 113 ? 25.238  14.909  74.151  1.00 27.25  ? 113 THR G OG1 1 
ATOM   19872 C CG2 . THR G 1 113 ? 24.881  15.431  71.807  1.00 25.05  ? 113 THR G CG2 1 
ATOM   19873 N N   . ARG G 1 114 ? 27.283  17.604  74.710  1.00 26.37  ? 114 ARG G N   1 
ATOM   19874 C CA  . ARG G 1 114 ? 27.685  18.098  76.033  1.00 29.71  ? 114 ARG G CA  1 
ATOM   19875 C C   . ARG G 1 114 ? 27.090  17.242  77.149  1.00 24.65  ? 114 ARG G C   1 
ATOM   19876 O O   . ARG G 1 114 ? 27.778  16.873  78.109  1.00 24.27  ? 114 ARG G O   1 
ATOM   19877 C CB  . ARG G 1 114 ? 27.252  19.567  76.203  1.00 27.89  ? 114 ARG G CB  1 
ATOM   19878 C CG  . ARG G 1 114 ? 27.743  20.286  77.497  1.00 26.08  ? 114 ARG G CG  1 
ATOM   19879 C CD  . ARG G 1 114 ? 27.132  21.699  77.574  1.00 30.42  ? 114 ARG G CD  1 
ATOM   19880 N NE  . ARG G 1 114 ? 27.128  22.331  78.895  1.00 30.28  ? 114 ARG G NE  1 
ATOM   19881 C CZ  . ARG G 1 114 ? 28.213  22.736  79.550  1.00 35.43  ? 114 ARG G CZ  1 
ATOM   19882 N NH1 . ARG G 1 114 ? 29.431  22.503  79.092  1.00 32.75  ? 114 ARG G NH1 1 
ATOM   19883 N NH2 . ARG G 1 114 ? 28.074  23.390  80.702  1.00 37.32  ? 114 ARG G NH2 1 
ATOM   19884 N N   . ALA G 1 115 ? 25.802  16.938  77.049  1.00 24.85  ? 115 ALA G N   1 
ATOM   19885 C CA  . ALA G 1 115 ? 25.164  16.137  78.085  1.00 26.36  ? 115 ALA G CA  1 
ATOM   19886 C C   . ALA G 1 115 ? 25.704  14.711  78.115  1.00 24.38  ? 115 ALA G C   1 
ATOM   19887 O O   . ALA G 1 115 ? 25.807  14.122  79.194  1.00 24.97  ? 115 ALA G O   1 
ATOM   19888 C CB  . ALA G 1 115 ? 23.659  16.144  77.882  1.00 26.81  ? 115 ALA G CB  1 
ATOM   19889 N N   . ALA G 1 116 ? 26.065  14.141  76.958  1.00 22.92  ? 116 ALA G N   1 
ATOM   19890 C CA  . ALA G 1 116 ? 26.726  12.831  76.973  1.00 27.44  ? 116 ALA G CA  1 
ATOM   19891 C C   . ALA G 1 116 ? 28.079  12.905  77.667  1.00 24.74  ? 116 ALA G C   1 
ATOM   19892 O O   . ALA G 1 116 ? 28.470  11.972  78.383  1.00 28.84  ? 116 ALA G O   1 
ATOM   19893 C CB  . ALA G 1 116 ? 26.908  12.283  75.556  1.00 17.33  ? 116 ALA G CB  1 
ATOM   19894 N N   . ALA G 1 117 ? 28.813  13.995  77.449  1.00 23.64  ? 117 ALA G N   1 
ATOM   19895 C CA  . ALA G 1 117 ? 30.054  14.214  78.186  1.00 29.03  ? 117 ALA G CA  1 
ATOM   19896 C C   . ALA G 1 117 ? 29.792  14.275  79.685  1.00 26.61  ? 117 ALA G C   1 
ATOM   19897 O O   . ALA G 1 117 ? 30.438  13.569  80.467  1.00 27.46  ? 117 ALA G O   1 
ATOM   19898 C CB  . ALA G 1 117 ? 30.739  15.498  77.702  1.00 29.89  ? 117 ALA G CB  1 
ATOM   19899 N N   . GLN G 1 118 ? 28.831  15.106  80.101  1.00 30.53  ? 118 GLN G N   1 
ATOM   19900 C CA  . GLN G 1 118 ? 28.490  15.197  81.521  1.00 30.06  ? 118 GLN G CA  1 
ATOM   19901 C C   . GLN G 1 118 ? 28.067  13.840  82.070  1.00 29.85  ? 118 GLN G C   1 
ATOM   19902 O O   . GLN G 1 118 ? 28.395  13.484  83.211  1.00 31.65  ? 118 GLN G O   1 
ATOM   19903 C CB  . GLN G 1 118 ? 27.381  16.233  81.716  1.00 24.75  ? 118 GLN G CB  1 
ATOM   19904 C CG  . GLN G 1 118 ? 27.824  17.660  81.467  1.00 28.42  ? 118 GLN G CG  1 
ATOM   19905 C CD  . GLN G 1 118 ? 26.650  18.611  81.336  1.00 32.11  ? 118 GLN G CD  1 
ATOM   19906 O OE1 . GLN G 1 118 ? 25.637  18.275  80.726  1.00 34.70  ? 118 GLN G OE1 1 
ATOM   19907 N NE2 . GLN G 1 118 ? 26.773  19.802  81.923  1.00 30.07  ? 118 GLN G NE2 1 
ATOM   19908 N N   . LEU G 1 119 ? 27.369  13.057  81.248  1.00 29.11  ? 119 LEU G N   1 
ATOM   19909 C CA  . LEU G 1 119 ? 26.878  11.757  81.679  1.00 28.58  ? 119 LEU G CA  1 
ATOM   19910 C C   . LEU G 1 119 ? 28.015  10.845  82.101  1.00 33.07  ? 119 LEU G C   1 
ATOM   19911 O O   . LEU G 1 119 ? 27.875  10.091  83.069  1.00 37.77  ? 119 LEU G O   1 
ATOM   19912 C CB  . LEU G 1 119 ? 26.052  11.124  80.561  1.00 27.07  ? 119 LEU G CB  1 
ATOM   19913 C CG  . LEU G 1 119 ? 25.409  9.769   80.840  1.00 33.12  ? 119 LEU G CG  1 
ATOM   19914 C CD1 . LEU G 1 119 ? 24.487  9.803   82.087  1.00 28.15  ? 119 LEU G CD1 1 
ATOM   19915 C CD2 . LEU G 1 119 ? 24.644  9.350   79.613  1.00 24.49  ? 119 LEU G CD2 1 
ATOM   19916 N N   . THR G 1 120 ? 29.155  10.897  81.396  1.00 30.42  ? 120 THR G N   1 
ATOM   19917 C CA  . THR G 1 120 ? 30.278  10.041  81.778  1.00 30.56  ? 120 THR G CA  1 
ATOM   19918 C C   . THR G 1 120 ? 30.827  10.442  83.136  1.00 36.34  ? 120 THR G C   1 
ATOM   19919 O O   . THR G 1 120 ? 31.288  9.591   83.908  1.00 37.75  ? 120 THR G O   1 
ATOM   19920 C CB  . THR G 1 120 ? 31.417  10.079  80.740  1.00 29.33  ? 120 THR G CB  1 
ATOM   19921 O OG1 . THR G 1 120 ? 31.818  11.428  80.485  1.00 28.50  ? 120 THR G OG1 1 
ATOM   19922 C CG2 . THR G 1 120 ? 31.028  9.375   79.444  1.00 25.45  ? 120 THR G CG2 1 
ATOM   19923 N N   . ARG G 1 121 ? 30.814  11.738  83.435  1.00 36.31  ? 121 ARG G N   1 
ATOM   19924 C CA  . ARG G 1 121 ? 31.310  12.179  84.731  1.00 38.57  ? 121 ARG G CA  1 
ATOM   19925 C C   . ARG G 1 121 ? 30.339  11.806  85.846  1.00 32.10  ? 121 ARG G C   1 
ATOM   19926 O O   . ARG G 1 121 ? 30.765  11.400  86.929  1.00 38.66  ? 121 ARG G O   1 
ATOM   19927 C CB  . ARG G 1 121 ? 31.568  13.687  84.702  1.00 32.95  ? 121 ARG G CB  1 
ATOM   19928 C CG  . ARG G 1 121 ? 32.515  14.149  85.795  1.00 38.24  ? 121 ARG G CG  1 
ATOM   19929 C CD  . ARG G 1 121 ? 33.650  14.996  85.245  1.00 44.32  ? 121 ARG G CD  1 
ATOM   19930 N NE  . ARG G 1 121 ? 34.488  14.264  84.301  1.00 48.91  ? 121 ARG G NE  1 
ATOM   19931 C CZ  . ARG G 1 121 ? 35.547  14.787  83.695  1.00 50.75  ? 121 ARG G CZ  1 
ATOM   19932 N NH1 . ARG G 1 121 ? 35.926  16.034  83.927  1.00 45.16  ? 121 ARG G NH1 1 
ATOM   19933 N NH2 . ARG G 1 121 ? 36.250  14.037  82.847  1.00 47.32  ? 121 ARG G NH2 1 
ATOM   19934 N N   . LYS G 1 122 ? 29.032  11.907  85.594  1.00 35.66  ? 122 LYS G N   1 
ATOM   19935 C CA  . LYS G 1 122 ? 28.042  11.657  86.643  1.00 38.11  ? 122 LYS G CA  1 
ATOM   19936 C C   . LYS G 1 122 ? 27.914  10.184  87.013  1.00 38.96  ? 122 LYS G C   1 
ATOM   19937 O O   . LYS G 1 122 ? 27.482  9.874   88.129  1.00 41.46  ? 122 LYS G O   1 
ATOM   19938 C CB  . LYS G 1 122 ? 26.687  12.206  86.217  1.00 38.83  ? 122 LYS G CB  1 
ATOM   19939 C CG  . LYS G 1 122 ? 26.633  13.712  86.278  1.00 40.10  ? 122 LYS G CG  1 
ATOM   19940 C CD  . LYS G 1 122 ? 25.212  14.221  86.234  1.00 43.51  ? 122 LYS G CD  1 
ATOM   19941 C CE  . LYS G 1 122 ? 25.112  15.594  86.903  1.00 43.73  ? 122 LYS G CE  1 
ATOM   19942 N NZ  . LYS G 1 122 ? 25.063  15.521  88.393  1.00 49.42  ? 122 LYS G NZ  1 
ATOM   19943 N N   . LEU G 1 123 ? 28.265  9.273   86.108  1.00 40.40  ? 123 LEU G N   1 
ATOM   19944 C CA  . LEU G 1 123 ? 28.347  7.856   86.428  1.00 37.83  ? 123 LEU G CA  1 
ATOM   19945 C C   . LEU G 1 123 ? 29.762  7.415   86.777  1.00 39.39  ? 123 LEU G C   1 
ATOM   19946 O O   . LEU G 1 123 ? 29.945  6.290   87.246  1.00 43.64  ? 123 LEU G O   1 
ATOM   19947 C CB  . LEU G 1 123 ? 27.811  7.016   85.257  1.00 32.46  ? 123 LEU G CB  1 
ATOM   19948 C CG  . LEU G 1 123 ? 26.343  7.270   84.888  1.00 37.70  ? 123 LEU G CG  1 
ATOM   19949 C CD1 . LEU G 1 123 ? 25.969  6.712   83.506  1.00 32.83  ? 123 LEU G CD1 1 
ATOM   19950 C CD2 . LEU G 1 123 ? 25.406  6.711   85.962  1.00 42.95  ? 123 LEU G CD2 1 
ATOM   19951 N N   . ASN G 1 124 ? 30.757  8.279   86.568  1.00 40.42  ? 124 ASN G N   1 
ATOM   19952 C CA  . ASN G 1 124 ? 32.169  7.966   86.797  1.00 41.13  ? 124 ASN G CA  1 
ATOM   19953 C C   . ASN G 1 124 ? 32.638  6.798   85.934  1.00 43.38  ? 124 ASN G C   1 
ATOM   19954 O O   . ASN G 1 124 ? 33.540  6.042   86.319  1.00 44.96  ? 124 ASN G O   1 
ATOM   19955 C CB  . ASN G 1 124 ? 32.458  7.698   88.278  1.00 45.31  ? 124 ASN G CB  1 
ATOM   19956 C CG  . ASN G 1 124 ? 33.668  8.465   88.779  1.00 50.64  ? 124 ASN G CG  1 
ATOM   19957 O OD1 . ASN G 1 124 ? 34.810  8.161   88.426  1.00 59.61  ? 124 ASN G OD1 1 
ATOM   19958 N ND2 . ASN G 1 124 ? 33.418  9.496   89.581  1.00 57.25  ? 124 ASN G ND2 1 
ATOM   19959 N N   . VAL G 1 125 ? 32.050  6.643   84.747  1.00 36.48  ? 125 VAL G N   1 
ATOM   19960 C CA  . VAL G 1 125 ? 32.549  5.636   83.819  1.00 40.15  ? 125 VAL G CA  1 
ATOM   19961 C C   . VAL G 1 125 ? 33.775  6.225   83.135  1.00 37.68  ? 125 VAL G C   1 
ATOM   19962 O O   . VAL G 1 125 ? 34.198  7.343   83.457  1.00 34.14  ? 125 VAL G O   1 
ATOM   19963 C CB  . VAL G 1 125 ? 31.475  5.189   82.807  1.00 36.63  ? 125 VAL G CB  1 
ATOM   19964 C CG1 . VAL G 1 125 ? 30.220  4.755   83.541  1.00 33.78  ? 125 VAL G CG1 1 
ATOM   19965 C CG2 . VAL G 1 125 ? 31.153  6.302   81.819  1.00 31.44  ? 125 VAL G CG2 1 
ATOM   19966 N N   . ALA G 1 126 ? 34.371  5.467   82.215  1.00 34.91  ? 126 ALA G N   1 
ATOM   19967 C CA  . ALA G 1 126 ? 35.466  5.988   81.409  1.00 31.36  ? 126 ALA G CA  1 
ATOM   19968 C C   . ALA G 1 126 ? 35.079  7.334   80.810  1.00 30.58  ? 126 ALA G C   1 
ATOM   19969 O O   . ALA G 1 126 ? 33.978  7.498   80.280  1.00 30.16  ? 126 ALA G O   1 
ATOM   19970 C CB  . ALA G 1 126 ? 35.816  4.982   80.308  1.00 30.37  ? 126 ALA G CB  1 
ATOM   19971 N N   . ALA G 1 127 ? 35.962  8.317   80.940  1.00 37.10  ? 127 ALA G N   1 
ATOM   19972 C CA  . ALA G 1 127 ? 35.647  9.651   80.431  1.00 37.74  ? 127 ALA G CA  1 
ATOM   19973 C C   . ALA G 1 127 ? 35.386  9.613   78.925  1.00 35.86  ? 127 ALA G C   1 
ATOM   19974 O O   . ALA G 1 127 ? 36.038  8.871   78.181  1.00 32.37  ? 127 ALA G O   1 
ATOM   19975 C CB  . ALA G 1 127 ? 36.781  10.632  80.747  1.00 37.14  ? 127 ALA G CB  1 
ATOM   19976 N N   . LEU G 1 128 ? 34.404  10.401  78.483  1.00 29.17  ? 128 LEU G N   1 
ATOM   19977 C CA  . LEU G 1 128 ? 34.113  10.516  77.063  1.00 30.73  ? 128 LEU G CA  1 
ATOM   19978 C C   . LEU G 1 128 ? 35.350  11.025  76.330  1.00 34.22  ? 128 LEU G C   1 
ATOM   19979 O O   . LEU G 1 128 ? 35.930  12.046  76.707  1.00 30.38  ? 128 LEU G O   1 
ATOM   19980 C CB  . LEU G 1 128 ? 32.929  11.463  76.848  1.00 32.54  ? 128 LEU G CB  1 
ATOM   19981 C CG  . LEU G 1 128 ? 32.553  11.771  75.400  1.00 32.62  ? 128 LEU G CG  1 
ATOM   19982 C CD1 . LEU G 1 128 ? 32.200  10.487  74.724  1.00 35.41  ? 128 LEU G CD1 1 
ATOM   19983 C CD2 . LEU G 1 128 ? 31.379  12.741  75.302  1.00 35.97  ? 128 LEU G CD2 1 
ATOM   19984 N N   . ASP G 1 129 ? 35.781  10.300  75.303  1.00 35.32  ? 129 ASP G N   1 
ATOM   19985 C CA  . ASP G 1 129 ? 36.972  10.723  74.580  1.00 34.19  ? 129 ASP G CA  1 
ATOM   19986 C C   . ASP G 1 129 ? 36.697  12.061  73.898  1.00 32.68  ? 129 ASP G C   1 
ATOM   19987 O O   . ASP G 1 129 ? 35.624  12.288  73.336  1.00 26.57  ? 129 ASP G O   1 
ATOM   19988 C CB  . ASP G 1 129 ? 37.386  9.650   73.570  1.00 33.57  ? 129 ASP G CB  1 
ATOM   19989 C CG  . ASP G 1 129 ? 38.833  9.780   73.127  1.00 31.71  ? 129 ASP G CG  1 
ATOM   19990 O OD1 . ASP G 1 129 ? 39.586  10.568  73.748  1.00 33.62  ? 129 ASP G OD1 1 
ATOM   19991 O OD2 . ASP G 1 129 ? 39.218  9.080   72.154  1.00 30.87  ? 129 ASP G OD2 1 
ATOM   19992 N N   . GLY G 1 130 ? 37.662  12.964  73.969  1.00 29.83  ? 130 GLY G N   1 
ATOM   19993 C CA  . GLY G 1 130 ? 37.364  14.306  73.516  1.00 29.19  ? 130 GLY G CA  1 
ATOM   19994 C C   . GLY G 1 130 ? 36.355  14.992  74.408  1.00 32.39  ? 130 GLY G C   1 
ATOM   19995 O O   . GLY G 1 130 ? 35.487  15.723  73.903  1.00 25.14  ? 130 GLY G O   1 
ATOM   19996 N N   . TYR G 1 131 ? 36.453  14.763  75.730  1.00 31.98  ? 131 TYR G N   1 
ATOM   19997 C CA  . TYR G 1 131 ? 35.533  15.339  76.710  1.00 30.27  ? 131 TYR G CA  1 
ATOM   19998 C C   . TYR G 1 131 ? 35.387  16.856  76.550  1.00 29.41  ? 131 TYR G C   1 
ATOM   19999 O O   . TYR G 1 131 ? 34.268  17.375  76.440  1.00 26.98  ? 131 TYR G O   1 
ATOM   20000 C CB  . TYR G 1 131 ? 36.009  14.982  78.131  1.00 31.18  ? 131 TYR G CB  1 
ATOM   20001 C CG  . TYR G 1 131 ? 35.171  15.565  79.259  1.00 36.13  ? 131 TYR G CG  1 
ATOM   20002 C CD1 . TYR G 1 131 ? 34.067  14.881  79.754  1.00 33.79  ? 131 TYR G CD1 1 
ATOM   20003 C CD2 . TYR G 1 131 ? 35.495  16.787  79.839  1.00 37.04  ? 131 TYR G CD2 1 
ATOM   20004 C CE1 . TYR G 1 131 ? 33.296  15.406  80.768  1.00 35.32  ? 131 TYR G CE1 1 
ATOM   20005 C CE2 . TYR G 1 131 ? 34.734  17.322  80.868  1.00 33.92  ? 131 TYR G CE2 1 
ATOM   20006 C CZ  . TYR G 1 131 ? 33.633  16.628  81.328  1.00 37.13  ? 131 TYR G CZ  1 
ATOM   20007 O OH  . TYR G 1 131 ? 32.863  17.148  82.349  1.00 30.53  ? 131 TYR G OH  1 
ATOM   20008 N N   . GLU G 1 132 ? 36.505  17.587  76.533  1.00 26.21  ? 132 GLU G N   1 
ATOM   20009 C CA  . GLU G 1 132 ? 36.402  19.048  76.539  1.00 31.00  ? 132 GLU G CA  1 
ATOM   20010 C C   . GLU G 1 132 ? 35.784  19.575  75.250  1.00 24.64  ? 132 GLU G C   1 
ATOM   20011 O O   . GLU G 1 132 ? 35.024  20.540  75.282  1.00 20.88  ? 132 GLU G O   1 
ATOM   20012 C CB  . GLU G 1 132 ? 37.768  19.694  76.768  1.00 29.21  ? 132 GLU G CB  1 
ATOM   20013 C CG  . GLU G 1 132 ? 38.392  19.397  78.107  1.00 29.05  ? 132 GLU G CG  1 
ATOM   20014 C CD  . GLU G 1 132 ? 37.567  19.929  79.280  1.00 39.32  ? 132 GLU G CD  1 
ATOM   20015 O OE1 . GLU G 1 132 ? 36.668  20.796  79.064  1.00 35.05  ? 132 GLU G OE1 1 
ATOM   20016 O OE2 . GLU G 1 132 ? 37.831  19.463  80.421  1.00 34.61  ? 132 GLU G OE2 1 
ATOM   20017 N N   . PHE G 1 133 ? 36.104  18.959  74.108  1.00 25.71  ? 133 PHE G N   1 
ATOM   20018 C CA  . PHE G 1 133 ? 35.472  19.339  72.843  1.00 27.34  ? 133 PHE G CA  1 
ATOM   20019 C C   . PHE G 1 133 ? 33.961  19.152  72.919  1.00 25.03  ? 133 PHE G C   1 
ATOM   20020 O O   . PHE G 1 133 ? 33.187  20.023  72.513  1.00 23.93  ? 133 PHE G O   1 
ATOM   20021 C CB  . PHE G 1 133 ? 36.073  18.506  71.700  1.00 24.96  ? 133 PHE G CB  1 
ATOM   20022 C CG  . PHE G 1 133 ? 35.698  18.971  70.312  1.00 26.37  ? 133 PHE G CG  1 
ATOM   20023 C CD1 . PHE G 1 133 ? 36.122  20.214  69.830  1.00 25.14  ? 133 PHE G CD1 1 
ATOM   20024 C CD2 . PHE G 1 133 ? 34.953  18.152  69.477  1.00 22.53  ? 133 PHE G CD2 1 
ATOM   20025 C CE1 . PHE G 1 133 ? 35.796  20.633  68.550  1.00 24.11  ? 133 PHE G CE1 1 
ATOM   20026 C CE2 . PHE G 1 133 ? 34.637  18.552  68.188  1.00 27.11  ? 133 PHE G CE2 1 
ATOM   20027 C CZ  . PHE G 1 133 ? 35.064  19.803  67.720  1.00 23.27  ? 133 PHE G CZ  1 
ATOM   20028 N N   . ALA G 1 134 ? 33.520  18.018  73.458  1.00 30.08  ? 134 ALA G N   1 
ATOM   20029 C CA  . ALA G 1 134 ? 32.088  17.780  73.584  1.00 26.63  ? 134 ALA G CA  1 
ATOM   20030 C C   . ALA G 1 134 ? 31.442  18.802  74.510  1.00 26.60  ? 134 ALA G C   1 
ATOM   20031 O O   . ALA G 1 134 ? 30.313  19.252  74.265  1.00 21.81  ? 134 ALA G O   1 
ATOM   20032 C CB  . ALA G 1 134 ? 31.847  16.360  74.091  1.00 24.76  ? 134 ALA G CB  1 
ATOM   20033 N N   . MET G 1 135 ? 32.148  19.183  75.580  1.00 26.92  ? 135 MET G N   1 
ATOM   20034 C CA  . MET G 1 135 ? 31.587  20.124  76.546  1.00 27.46  ? 135 MET G CA  1 
ATOM   20035 C C   . MET G 1 135 ? 31.288  21.489  75.932  1.00 26.23  ? 135 MET G C   1 
ATOM   20036 O O   . MET G 1 135 ? 30.331  22.144  76.345  1.00 28.94  ? 135 MET G O   1 
ATOM   20037 C CB  . MET G 1 135 ? 32.523  20.249  77.749  1.00 29.84  ? 135 MET G CB  1 
ATOM   20038 C CG  . MET G 1 135 ? 32.564  18.960  78.604  1.00 33.62  ? 135 MET G CG  1 
ATOM   20039 S SD  . MET G 1 135 ? 31.010  18.573  79.498  1.00 37.17  ? 135 MET G SD  1 
ATOM   20040 C CE  . MET G 1 135 ? 30.899  19.926  80.670  1.00 30.65  ? 135 MET G CE  1 
ATOM   20041 N N   . GLN G 1 136 ? 32.076  21.943  74.956  1.00 26.38  ? 136 GLN G N   1 
ATOM   20042 C CA  . GLN G 1 136 ? 31.753  23.167  74.232  1.00 25.66  ? 136 GLN G CA  1 
ATOM   20043 C C   . GLN G 1 136 ? 30.838  22.911  73.033  1.00 27.34  ? 136 GLN G C   1 
ATOM   20044 O O   . GLN G 1 136 ? 30.703  23.796  72.172  1.00 25.69  ? 136 GLN G O   1 
ATOM   20045 C CB  . GLN G 1 136 ? 33.035  23.879  73.758  1.00 23.64  ? 136 GLN G CB  1 
ATOM   20046 C CG  . GLN G 1 136 ? 34.122  24.093  74.843  1.00 30.30  ? 136 GLN G CG  1 
ATOM   20047 C CD  . GLN G 1 136 ? 33.631  24.869  76.046  1.00 24.39  ? 136 GLN G CD  1 
ATOM   20048 O OE1 . GLN G 1 136 ? 33.091  25.938  75.899  1.00 27.16  ? 136 GLN G OE1 1 
ATOM   20049 N NE2 . GLN G 1 136 ? 33.796  24.307  77.246  1.00 27.96  ? 136 GLN G NE2 1 
ATOM   20050 N N   . ASN G 1 137 ? 30.218  21.728  72.961  1.00 23.61  ? 137 ASN G N   1 
ATOM   20051 C CA  . ASN G 1 137 ? 29.398  21.311  71.822  1.00 27.19  ? 137 ASN G CA  1 
ATOM   20052 C C   . ASN G 1 137 ? 30.148  21.517  70.509  1.00 32.08  ? 137 ASN G C   1 
ATOM   20053 O O   . ASN G 1 137 ? 29.645  22.134  69.560  1.00 26.13  ? 137 ASN G O   1 
ATOM   20054 C CB  . ASN G 1 137 ? 28.055  22.046  71.798  1.00 31.73  ? 137 ASN G CB  1 
ATOM   20055 C CG  . ASN G 1 137 ? 27.106  21.559  72.874  1.00 30.89  ? 137 ASN G CG  1 
ATOM   20056 O OD1 . ASN G 1 137 ? 26.704  20.389  72.896  1.00 33.11  ? 137 ASN G OD1 1 
ATOM   20057 N ND2 . ASN G 1 137 ? 26.744  22.452  73.769  1.00 29.08  ? 137 ASN G ND2 1 
ATOM   20058 N N   . GLY G 1 138 ? 31.393  21.031  70.482  1.00 23.51  ? 138 GLY G N   1 
ATOM   20059 C CA  . GLY G 1 138 ? 32.162  21.097  69.257  1.00 27.85  ? 138 GLY G CA  1 
ATOM   20060 C C   . GLY G 1 138 ? 31.520  20.316  68.129  1.00 26.61  ? 138 GLY G C   1 
ATOM   20061 O O   . GLY G 1 138 ? 31.663  20.674  66.961  1.00 25.57  ? 138 GLY G O   1 
ATOM   20062 N N   . ILE G 1 139 ? 30.781  19.256  68.460  1.00 26.67  ? 139 ILE G N   1 
ATOM   20063 C CA  . ILE G 1 139 ? 30.212  18.417  67.416  1.00 25.61  ? 139 ILE G CA  1 
ATOM   20064 C C   . ILE G 1 139 ? 29.146  19.181  66.630  1.00 31.12  ? 139 ILE G C   1 
ATOM   20065 O O   . ILE G 1 139 ? 29.021  19.009  65.409  1.00 28.32  ? 139 ILE G O   1 
ATOM   20066 C CB  . ILE G 1 139 ? 29.687  17.109  68.034  1.00 31.43  ? 139 ILE G CB  1 
ATOM   20067 C CG1 . ILE G 1 139 ? 30.854  16.130  68.261  1.00 25.05  ? 139 ILE G CG1 1 
ATOM   20068 C CG2 . ILE G 1 139 ? 28.616  16.484  67.158  1.00 31.36  ? 139 ILE G CG2 1 
ATOM   20069 C CD1 . ILE G 1 139 ? 31.736  16.451  69.474  1.00 26.93  ? 139 ILE G CD1 1 
ATOM   20070 N N   . ASP G 1 140 ? 28.410  20.080  67.289  1.00 31.26  ? 140 ASP G N   1 
ATOM   20071 C CA  . ASP G 1 140 ? 27.472  20.931  66.561  1.00 34.17  ? 140 ASP G CA  1 
ATOM   20072 C C   . ASP G 1 140 ? 28.192  21.871  65.595  1.00 31.64  ? 140 ASP G C   1 
ATOM   20073 O O   . ASP G 1 140 ? 27.663  22.176  64.521  1.00 32.56  ? 140 ASP G O   1 
ATOM   20074 C CB  . ASP G 1 140 ? 26.602  21.711  67.548  1.00 40.55  ? 140 ASP G CB  1 
ATOM   20075 C CG  . ASP G 1 140 ? 25.361  20.924  67.983  1.00 50.46  ? 140 ASP G CG  1 
ATOM   20076 O OD1 . ASP G 1 140 ? 25.511  19.725  68.333  1.00 48.67  ? 140 ASP G OD1 1 
ATOM   20077 O OD2 . ASP G 1 140 ? 24.241  21.498  67.983  1.00 53.81  ? 140 ASP G OD2 1 
ATOM   20078 N N   . LEU G 1 141 ? 29.402  22.315  65.935  1.00 28.50  ? 141 LEU G N   1 
ATOM   20079 C CA  . LEU G 1 141 ? 30.215  23.037  64.960  1.00 30.90  ? 141 LEU G CA  1 
ATOM   20080 C C   . LEU G 1 141 ? 30.449  22.202  63.700  1.00 27.61  ? 141 LEU G C   1 
ATOM   20081 O O   . LEU G 1 141 ? 30.215  22.675  62.582  1.00 23.86  ? 141 LEU G O   1 
ATOM   20082 C CB  . LEU G 1 141 ? 31.549  23.450  65.587  1.00 27.76  ? 141 LEU G CB  1 
ATOM   20083 C CG  . LEU G 1 141 ? 32.603  24.066  64.660  1.00 28.04  ? 141 LEU G CG  1 
ATOM   20084 C CD1 . LEU G 1 141 ? 31.991  25.195  63.844  1.00 25.50  ? 141 LEU G CD1 1 
ATOM   20085 C CD2 . LEU G 1 141 ? 33.795  24.577  65.468  1.00 27.38  ? 141 LEU G CD2 1 
ATOM   20086 N N   . LEU G 1 142 ? 30.902  20.948  63.864  1.00 19.61  ? 142 LEU G N   1 
ATOM   20087 C CA  . LEU G 1 142 ? 31.279  20.112  62.723  1.00 27.08  ? 142 LEU G CA  1 
ATOM   20088 C C   . LEU G 1 142 ? 30.096  19.622  61.882  1.00 23.08  ? 142 LEU G C   1 
ATOM   20089 O O   . LEU G 1 142 ? 30.297  19.260  60.724  1.00 27.24  ? 142 LEU G O   1 
ATOM   20090 C CB  . LEU G 1 142 ? 32.094  18.901  63.198  1.00 27.54  ? 142 LEU G CB  1 
ATOM   20091 C CG  . LEU G 1 142 ? 33.313  19.163  64.085  1.00 21.48  ? 142 LEU G CG  1 
ATOM   20092 C CD1 . LEU G 1 142 ? 33.992  17.861  64.410  1.00 21.68  ? 142 LEU G CD1 1 
ATOM   20093 C CD2 . LEU G 1 142 ? 34.287  20.143  63.431  1.00 18.52  ? 142 LEU G CD2 1 
ATOM   20094 N N   . ASN G 1 143 ? 28.880  19.593  62.414  1.00 24.42  ? 143 ASN G N   1 
ATOM   20095 C CA  . ASN G 1 143 ? 27.725  19.084  61.684  1.00 24.34  ? 143 ASN G CA  1 
ATOM   20096 C C   . ASN G 1 143 ? 26.944  20.194  60.965  1.00 28.16  ? 143 ASN G C   1 
ATOM   20097 O O   . ASN G 1 143 ? 25.751  20.041  60.683  1.00 38.97  ? 143 ASN G O   1 
ATOM   20098 C CB  . ASN G 1 143 ? 26.818  18.302  62.642  1.00 22.69  ? 143 ASN G CB  1 
ATOM   20099 C CG  . ASN G 1 143 ? 27.412  16.935  62.997  1.00 31.88  ? 143 ASN G CG  1 
ATOM   20100 O OD1 . ASN G 1 143 ? 28.131  16.345  62.190  1.00 27.70  ? 143 ASN G OD1 1 
ATOM   20101 N ND2 . ASN G 1 143 ? 27.135  16.445  64.198  1.00 24.90  ? 143 ASN G ND2 1 
ATOM   20102 N N   . MET G 1 144 ? 27.581  21.313  60.685  1.00 24.08  ? 144 MET G N   1 
ATOM   20103 C CA  . MET G 1 144 ? 27.007  22.319  59.820  1.00 27.95  ? 144 MET G CA  1 
ATOM   20104 C C   . MET G 1 144 ? 27.610  22.169  58.432  1.00 26.99  ? 144 MET G C   1 
ATOM   20105 O O   . MET G 1 144 ? 28.835  22.097  58.282  1.00 26.92  ? 144 MET G O   1 
ATOM   20106 C CB  . MET G 1 144 ? 27.224  23.724  60.386  1.00 27.02  ? 144 MET G CB  1 
ATOM   20107 C CG  . MET G 1 144 ? 26.627  23.933  61.777  1.00 27.55  ? 144 MET G CG  1 
ATOM   20108 S SD  . MET G 1 144 ? 27.393  25.353  62.605  1.00 31.76  ? 144 MET G SD  1 
ATOM   20109 C CE  . MET G 1 144 ? 26.433  26.716  61.943  1.00 32.39  ? 144 MET G CE  1 
ATOM   20110 N N   . LYS G 1 145 ? 26.746  22.079  57.423  1.00 24.43  ? 145 LYS G N   1 
ATOM   20111 C CA  . LYS G 1 145 ? 27.242  21.970  56.055  1.00 28.21  ? 145 LYS G CA  1 
ATOM   20112 C C   . LYS G 1 145 ? 28.061  23.187  55.665  1.00 25.06  ? 145 LYS G C   1 
ATOM   20113 O O   . LYS G 1 145 ? 28.997  23.067  54.863  1.00 22.00  ? 145 LYS G O   1 
ATOM   20114 C CB  . LYS G 1 145 ? 26.074  21.761  55.089  1.00 29.48  ? 145 LYS G CB  1 
ATOM   20115 C CG  . LYS G 1 145 ? 25.236  20.560  55.479  1.00 25.69  ? 145 LYS G CG  1 
ATOM   20116 C CD  . LYS G 1 145 ? 24.030  20.406  54.584  1.00 33.76  ? 145 LYS G CD  1 
ATOM   20117 C CE  . LYS G 1 145 ? 23.101  19.346  55.144  1.00 35.68  ? 145 LYS G CE  1 
ATOM   20118 N NZ  . LYS G 1 145 ? 22.733  19.626  56.568  1.00 35.56  ? 145 LYS G NZ  1 
ATOM   20119 N N   . SER G 1 146 ? 27.751  24.354  56.250  1.00 19.86  ? 146 SER G N   1 
ATOM   20120 C CA  . SER G 1 146 ? 28.563  25.544  56.013  1.00 24.86  ? 146 SER G CA  1 
ATOM   20121 C C   . SER G 1 146 ? 29.976  25.365  56.565  1.00 27.29  ? 146 SER G C   1 
ATOM   20122 O O   . SER G 1 146 ? 30.953  25.814  55.948  1.00 22.05  ? 146 SER G O   1 
ATOM   20123 C CB  . SER G 1 146 ? 27.894  26.775  56.633  1.00 22.66  ? 146 SER G CB  1 
ATOM   20124 O OG  . SER G 1 146 ? 27.831  26.661  58.044  1.00 24.35  ? 146 SER G OG  1 
ATOM   20125 N N   . THR G 1 147 ? 30.102  24.732  57.739  1.00 22.53  ? 147 THR G N   1 
ATOM   20126 C CA  . THR G 1 147 ? 31.426  24.468  58.289  1.00 21.00  ? 147 THR G CA  1 
ATOM   20127 C C   . THR G 1 147 ? 32.207  23.528  57.385  1.00 23.85  ? 147 THR G C   1 
ATOM   20128 O O   . THR G 1 147 ? 33.415  23.698  57.201  1.00 17.50  ? 147 THR G O   1 
ATOM   20129 C CB  . THR G 1 147 ? 31.326  23.880  59.700  1.00 22.65  ? 147 THR G CB  1 
ATOM   20130 O OG1 . THR G 1 147 ? 30.640  24.794  60.548  1.00 25.82  ? 147 THR G OG1 1 
ATOM   20131 C CG2 . THR G 1 147 ? 32.718  23.633  60.290  1.00 24.95  ? 147 THR G CG2 1 
ATOM   20132 N N   . PHE G 1 148 ? 31.531  22.535  56.797  1.00 22.49  ? 148 PHE G N   1 
ATOM   20133 C CA  . PHE G 1 148 ? 32.225  21.649  55.876  1.00 20.02  ? 148 PHE G CA  1 
ATOM   20134 C C   . PHE G 1 148 ? 32.767  22.406  54.669  1.00 22.94  ? 148 PHE G C   1 
ATOM   20135 O O   . PHE G 1 148 ? 33.881  22.128  54.205  1.00 22.38  ? 148 PHE G O   1 
ATOM   20136 C CB  . PHE G 1 148 ? 31.307  20.532  55.391  1.00 22.43  ? 148 PHE G CB  1 
ATOM   20137 C CG  . PHE G 1 148 ? 31.942  19.694  54.319  1.00 24.22  ? 148 PHE G CG  1 
ATOM   20138 C CD1 . PHE G 1 148 ? 32.870  18.722  54.651  1.00 24.00  ? 148 PHE G CD1 1 
ATOM   20139 C CD2 . PHE G 1 148 ? 31.667  19.921  52.993  1.00 21.91  ? 148 PHE G CD2 1 
ATOM   20140 C CE1 . PHE G 1 148 ? 33.467  17.965  53.677  1.00 24.15  ? 148 PHE G CE1 1 
ATOM   20141 C CE2 . PHE G 1 148 ? 32.265  19.173  52.024  1.00 27.25  ? 148 PHE G CE2 1 
ATOM   20142 C CZ  . PHE G 1 148 ? 33.173  18.190  52.360  1.00 23.62  ? 148 PHE G CZ  1 
ATOM   20143 N N   . ARG G 1 149 ? 31.978  23.330  54.112  1.00 19.13  ? 149 ARG G N   1 
ATOM   20144 C CA  . ARG G 1 149 ? 32.432  24.032  52.917  1.00 25.40  ? 149 ARG G CA  1 
ATOM   20145 C C   . ARG G 1 149 ? 33.647  24.885  53.221  1.00 20.69  ? 149 ARG G C   1 
ATOM   20146 O O   . ARG G 1 149 ? 34.566  24.983  52.401  1.00 21.62  ? 149 ARG G O   1 
ATOM   20147 C CB  . ARG G 1 149 ? 31.304  24.890  52.330  1.00 20.53  ? 149 ARG G CB  1 
ATOM   20148 C CG  . ARG G 1 149 ? 30.239  24.043  51.621  1.00 20.36  ? 149 ARG G CG  1 
ATOM   20149 C CD  . ARG G 1 149 ? 29.349  24.917  50.809  1.00 26.16  ? 149 ARG G CD  1 
ATOM   20150 N NE  . ARG G 1 149 ? 30.102  25.493  49.711  1.00 29.59  ? 149 ARG G NE  1 
ATOM   20151 C CZ  . ARG G 1 149 ? 30.429  24.835  48.607  1.00 27.89  ? 149 ARG G CZ  1 
ATOM   20152 N NH1 . ARG G 1 149 ? 30.016  23.598  48.392  1.00 30.59  ? 149 ARG G NH1 1 
ATOM   20153 N NH2 . ARG G 1 149 ? 31.187  25.435  47.693  1.00 26.30  ? 149 ARG G NH2 1 
ATOM   20154 N N   . ARG G 1 150 ? 33.684  25.476  54.418  1.00 21.91  ? 150 ARG G N   1 
ATOM   20155 C CA  . ARG G 1 150 ? 34.796  26.336  54.785  1.00 18.78  ? 150 ARG G CA  1 
ATOM   20156 C C   . ARG G 1 150 ? 36.053  25.528  55.049  1.00 18.08  ? 150 ARG G C   1 
ATOM   20157 O O   . ARG G 1 150 ? 37.121  25.848  54.526  1.00 26.86  ? 150 ARG G O   1 
ATOM   20158 C CB  . ARG G 1 150 ? 34.415  27.169  56.000  1.00 19.18  ? 150 ARG G CB  1 
ATOM   20159 C CG  . ARG G 1 150 ? 33.418  28.252  55.631  1.00 25.87  ? 150 ARG G CG  1 
ATOM   20160 C CD  . ARG G 1 150 ? 32.592  28.615  56.819  1.00 21.35  ? 150 ARG G CD  1 
ATOM   20161 N NE  . ARG G 1 150 ? 31.853  29.845  56.578  1.00 28.06  ? 150 ARG G NE  1 
ATOM   20162 C CZ  . ARG G 1 150 ? 31.034  30.399  57.463  1.00 28.00  ? 150 ARG G CZ  1 
ATOM   20163 N NH1 . ARG G 1 150 ? 30.868  29.878  58.676  1.00 21.95  ? 150 ARG G NH1 1 
ATOM   20164 N NH2 . ARG G 1 150 ? 30.369  31.497  57.126  1.00 26.22  ? 150 ARG G NH2 1 
ATOM   20165 N N   . LEU G 1 151 ? 35.959  24.489  55.877  1.00 19.73  ? 151 LEU G N   1 
ATOM   20166 C CA  . LEU G 1 151 ? 37.136  23.664  56.141  1.00 20.13  ? 151 LEU G CA  1 
ATOM   20167 C C   . LEU G 1 151 ? 37.662  23.030  54.860  1.00 21.96  ? 151 LEU G C   1 
ATOM   20168 O O   . LEU G 1 151 ? 38.875  22.973  54.645  1.00 23.90  ? 151 LEU G O   1 
ATOM   20169 C CB  . LEU G 1 151 ? 36.806  22.579  57.162  1.00 18.18  ? 151 LEU G CB  1 
ATOM   20170 C CG  . LEU G 1 151 ? 36.302  22.977  58.550  1.00 20.84  ? 151 LEU G CG  1 
ATOM   20171 C CD1 . LEU G 1 151 ? 36.255  21.722  59.449  1.00 18.35  ? 151 LEU G CD1 1 
ATOM   20172 C CD2 . LEU G 1 151 ? 37.148  24.042  59.181  1.00 22.20  ? 151 LEU G CD2 1 
ATOM   20173 N N   . ALA G 1 152 ? 36.767  22.546  53.996  1.00 20.28  ? 152 ALA G N   1 
ATOM   20174 C CA  . ALA G 1 152 ? 37.217  21.938  52.744  1.00 23.16  ? 152 ALA G CA  1 
ATOM   20175 C C   . ALA G 1 152 ? 37.861  22.977  51.838  1.00 25.14  ? 152 ALA G C   1 
ATOM   20176 O O   . ALA G 1 152 ? 38.961  22.762  51.312  1.00 21.91  ? 152 ALA G O   1 
ATOM   20177 C CB  . ALA G 1 152 ? 36.052  21.248  52.021  1.00 18.29  ? 152 ALA G CB  1 
ATOM   20178 N N   . ALA G 1 153 ? 37.190  24.120  51.652  1.00 26.22  ? 153 ALA G N   1 
ATOM   20179 C CA  . ALA G 1 153 ? 37.769  25.177  50.824  1.00 24.43  ? 153 ALA G CA  1 
ATOM   20180 C C   . ALA G 1 153 ? 39.143  25.576  51.334  1.00 25.05  ? 153 ALA G C   1 
ATOM   20181 O O   . ALA G 1 153 ? 40.064  25.816  50.550  1.00 27.33  ? 153 ALA G O   1 
ATOM   20182 C CB  . ALA G 1 153 ? 36.842  26.391  50.796  1.00 22.43  ? 153 ALA G CB  1 
ATOM   20183 N N   . GLY G 1 154 ? 39.303  25.644  52.654  1.00 24.61  ? 154 GLY G N   1 
ATOM   20184 C CA  . GLY G 1 154 ? 40.590  26.044  53.207  1.00 30.63  ? 154 GLY G CA  1 
ATOM   20185 C C   . GLY G 1 154 ? 41.666  24.992  53.009  1.00 26.94  ? 154 GLY G C   1 
ATOM   20186 O O   . GLY G 1 154 ? 42.802  25.317  52.668  1.00 28.57  ? 154 GLY G O   1 
ATOM   20187 N N   . LEU G 1 155 ? 41.318  23.721  53.196  1.00 26.92  ? 155 LEU G N   1 
ATOM   20188 C CA  . LEU G 1 155 ? 42.277  22.633  53.037  1.00 28.51  ? 155 LEU G CA  1 
ATOM   20189 C C   . LEU G 1 155 ? 42.567  22.306  51.580  1.00 31.18  ? 155 LEU G C   1 
ATOM   20190 O O   . LEU G 1 155 ? 43.622  21.735  51.283  1.00 35.70  ? 155 LEU G O   1 
ATOM   20191 C CB  . LEU G 1 155 ? 41.761  21.380  53.758  1.00 26.13  ? 155 LEU G CB  1 
ATOM   20192 C CG  . LEU G 1 155 ? 42.728  20.224  53.998  1.00 33.83  ? 155 LEU G CG  1 
ATOM   20193 C CD1 . LEU G 1 155 ? 43.958  20.672  54.781  1.00 28.51  ? 155 LEU G CD1 1 
ATOM   20194 C CD2 . LEU G 1 155 ? 42.014  19.130  54.746  1.00 25.51  ? 155 LEU G CD2 1 
ATOM   20195 N N   . GLY G 1 156 ? 41.679  22.667  50.665  1.00 29.92  ? 156 GLY G N   1 
ATOM   20196 C CA  . GLY G 1 156 ? 41.836  22.265  49.287  1.00 29.97  ? 156 GLY G CA  1 
ATOM   20197 C C   . GLY G 1 156 ? 41.159  20.965  48.924  1.00 33.79  ? 156 GLY G C   1 
ATOM   20198 O O   . GLY G 1 156 ? 41.418  20.442  47.836  1.00 36.61  ? 156 GLY G O   1 
ATOM   20199 N N   . THR G 1 157 ? 40.319  20.422  49.810  1.00 30.34  ? 157 THR G N   1 
ATOM   20200 C CA  . THR G 1 157 ? 39.534  19.229  49.517  1.00 27.32  ? 157 THR G CA  1 
ATOM   20201 C C   . THR G 1 157 ? 38.635  19.500  48.309  1.00 32.23  ? 157 THR G C   1 
ATOM   20202 O O   . THR G 1 157 ? 38.071  20.598  48.189  1.00 31.02  ? 157 THR G O   1 
ATOM   20203 C CB  . THR G 1 157 ? 38.686  18.849  50.750  1.00 34.55  ? 157 THR G CB  1 
ATOM   20204 O OG1 . THR G 1 157 ? 39.507  18.767  51.936  1.00 24.89  ? 157 THR G OG1 1 
ATOM   20205 C CG2 . THR G 1 157 ? 37.934  17.523  50.553  1.00 29.38  ? 157 THR G CG2 1 
ATOM   20206 N N   . PRO G 1 158 ? 38.500  18.550  47.381  1.00 32.20  ? 158 PRO G N   1 
ATOM   20207 C CA  . PRO G 1 158 ? 37.674  18.805  46.187  1.00 35.31  ? 158 PRO G CA  1 
ATOM   20208 C C   . PRO G 1 158 ? 36.223  19.050  46.575  1.00 31.99  ? 158 PRO G C   1 
ATOM   20209 O O   . PRO G 1 158 ? 35.647  18.311  47.375  1.00 32.99  ? 158 PRO G O   1 
ATOM   20210 C CB  . PRO G 1 158 ? 37.826  17.521  45.358  1.00 34.63  ? 158 PRO G CB  1 
ATOM   20211 C CG  . PRO G 1 158 ? 38.970  16.765  45.969  1.00 30.85  ? 158 PRO G CG  1 
ATOM   20212 C CD  . PRO G 1 158 ? 39.099  17.204  47.382  1.00 25.15  ? 158 PRO G CD  1 
ATOM   20213 N N   . LEU G 1 159 ? 35.627  20.081  45.981  1.00 28.08  ? 159 LEU G N   1 
ATOM   20214 C CA  . LEU G 1 159 ? 34.390  20.653  46.490  1.00 32.47  ? 159 LEU G CA  1 
ATOM   20215 C C   . LEU G 1 159 ? 33.607  21.296  45.352  1.00 31.29  ? 159 LEU G C   1 
ATOM   20216 O O   . LEU G 1 159 ? 34.196  22.008  44.534  1.00 28.83  ? 159 LEU G O   1 
ATOM   20217 C CB  . LEU G 1 159 ? 34.727  21.687  47.569  1.00 32.12  ? 159 LEU G CB  1 
ATOM   20218 C CG  . LEU G 1 159 ? 33.621  22.527  48.169  1.00 34.02  ? 159 LEU G CG  1 
ATOM   20219 C CD1 . LEU G 1 159 ? 32.728  21.660  49.041  1.00 29.85  ? 159 LEU G CD1 1 
ATOM   20220 C CD2 . LEU G 1 159 ? 34.219  23.675  48.977  1.00 31.17  ? 159 LEU G CD2 1 
ATOM   20221 N N   . THR G 1 160 ? 32.291  21.057  45.299  1.00 30.14  ? 160 THR G N   1 
ATOM   20222 C CA  . THR G 1 160 ? 31.486  21.700  44.262  1.00 31.24  ? 160 THR G CA  1 
ATOM   20223 C C   . THR G 1 160 ? 31.465  23.202  44.476  1.00 27.50  ? 160 THR G C   1 
ATOM   20224 O O   . THR G 1 160 ? 31.666  23.702  45.588  1.00 29.70  ? 160 THR G O   1 
ATOM   20225 C CB  . THR G 1 160 ? 30.034  21.178  44.225  1.00 33.51  ? 160 THR G CB  1 
ATOM   20226 O OG1 . THR G 1 160 ? 29.410  21.296  45.522  1.00 30.77  ? 160 THR G OG1 1 
ATOM   20227 C CG2 . THR G 1 160 ? 29.978  19.722  43.753  1.00 37.70  ? 160 THR G CG2 1 
ATOM   20228 N N   . ASP G 1 161 ? 31.241  23.925  43.379  1.00 31.10  ? 161 ASP G N   1 
ATOM   20229 C CA  . ASP G 1 161 ? 31.003  25.357  43.461  1.00 27.33  ? 161 ASP G CA  1 
ATOM   20230 C C   . ASP G 1 161 ? 29.737  25.617  44.264  1.00 29.27  ? 161 ASP G C   1 
ATOM   20231 O O   . ASP G 1 161 ? 28.708  24.973  44.051  1.00 27.86  ? 161 ASP G O   1 
ATOM   20232 C CB  . ASP G 1 161 ? 30.866  25.951  42.063  1.00 33.44  ? 161 ASP G CB  1 
ATOM   20233 C CG  . ASP G 1 161 ? 32.195  26.086  41.355  1.00 44.21  ? 161 ASP G CG  1 
ATOM   20234 O OD1 . ASP G 1 161 ? 33.250  26.042  42.034  1.00 45.46  ? 161 ASP G OD1 1 
ATOM   20235 O OD2 . ASP G 1 161 ? 32.180  26.224  40.116  1.00 49.65  ? 161 ASP G OD2 1 
ATOM   20236 N N   . GLY G 1 162 ? 29.814  26.564  45.188  1.00 27.18  ? 162 GLY G N   1 
ATOM   20237 C CA  . GLY G 1 162 ? 28.663  26.839  46.025  1.00 31.03  ? 162 GLY G CA  1 
ATOM   20238 C C   . GLY G 1 162 ? 28.891  28.079  46.859  1.00 30.23  ? 162 GLY G C   1 
ATOM   20239 O O   . GLY G 1 162 ? 29.951  28.708  46.801  1.00 28.20  ? 162 GLY G O   1 
ATOM   20240 N N   . VAL G 1 163 ? 27.864  28.424  47.635  1.00 23.12  ? 163 VAL G N   1 
ATOM   20241 C CA  . VAL G 1 163 ? 27.889  29.577  48.525  1.00 27.96  ? 163 VAL G CA  1 
ATOM   20242 C C   . VAL G 1 163 ? 27.264  29.179  49.850  1.00 30.65  ? 163 VAL G C   1 
ATOM   20243 O O   . VAL G 1 163 ? 26.259  28.455  49.891  1.00 27.76  ? 163 VAL G O   1 
ATOM   20244 C CB  . VAL G 1 163 ? 27.117  30.784  47.948  1.00 31.36  ? 163 VAL G CB  1 
ATOM   20245 C CG1 . VAL G 1 163 ? 25.740  30.361  47.708  1.00 29.98  ? 163 VAL G CG1 1 
ATOM   20246 C CG2 . VAL G 1 163 ? 27.044  31.913  48.957  1.00 29.00  ? 163 VAL G CG2 1 
ATOM   20247 N N   . VAL G 1 164 ? 27.877  29.645  50.934  1.00 26.03  ? 164 VAL G N   1 
ATOM   20248 C CA  . VAL G 1 164 ? 27.207  29.748  52.222  1.00 24.63  ? 164 VAL G CA  1 
ATOM   20249 C C   . VAL G 1 164 ? 26.420  31.059  52.181  1.00 26.05  ? 164 VAL G C   1 
ATOM   20250 O O   . VAL G 1 164 ? 26.987  32.136  52.336  1.00 27.54  ? 164 VAL G O   1 
ATOM   20251 C CB  . VAL G 1 164 ? 28.206  29.705  53.380  1.00 22.32  ? 164 VAL G CB  1 
ATOM   20252 C CG1 . VAL G 1 164 ? 27.508  29.841  54.711  1.00 24.63  ? 164 VAL G CG1 1 
ATOM   20253 C CG2 . VAL G 1 164 ? 29.052  28.417  53.301  1.00 25.53  ? 164 VAL G CG2 1 
ATOM   20254 N N   . ALA G 1 165 ? 25.116  30.979  51.942  1.00 22.46  ? 165 ALA G N   1 
ATOM   20255 C CA  . ALA G 1 165 ? 24.298  32.158  51.714  1.00 25.11  ? 165 ALA G CA  1 
ATOM   20256 C C   . ALA G 1 165 ? 23.708  32.674  53.020  1.00 29.47  ? 165 ALA G C   1 
ATOM   20257 O O   . ALA G 1 165 ? 23.311  31.896  53.895  1.00 30.07  ? 165 ALA G O   1 
ATOM   20258 C CB  . ALA G 1 165 ? 23.173  31.858  50.720  1.00 30.36  ? 165 ALA G CB  1 
ATOM   20259 N N   . ARG G 1 166 ? 23.652  33.998  53.143  1.00 25.70  ? 166 ARG G N   1 
ATOM   20260 C CA  . ARG G 1 166 ? 23.219  34.640  54.376  1.00 28.48  ? 166 ARG G CA  1 
ATOM   20261 C C   . ARG G 1 166 ? 21.865  35.329  54.254  1.00 28.61  ? 166 ARG G C   1 
ATOM   20262 O O   . ARG G 1 166 ? 21.399  35.908  55.232  1.00 25.88  ? 166 ARG G O   1 
ATOM   20263 C CB  . ARG G 1 166 ? 24.284  35.642  54.842  1.00 25.95  ? 166 ARG G CB  1 
ATOM   20264 C CG  . ARG G 1 166 ? 25.671  34.992  55.057  1.00 29.72  ? 166 ARG G CG  1 
ATOM   20265 C CD  . ARG G 1 166 ? 26.803  36.026  54.930  1.00 29.52  ? 166 ARG G CD  1 
ATOM   20266 N NE  . ARG G 1 166 ? 27.106  36.349  53.539  1.00 29.69  ? 166 ARG G NE  1 
ATOM   20267 C CZ  . ARG G 1 166 ? 28.058  37.196  53.159  1.00 31.60  ? 166 ARG G CZ  1 
ATOM   20268 N NH1 . ARG G 1 166 ? 28.821  37.816  54.044  1.00 29.88  ? 166 ARG G NH1 1 
ATOM   20269 N NH2 . ARG G 1 166 ? 28.252  37.419  51.857  1.00 23.00  ? 166 ARG G NH2 1 
ATOM   20270 N N   . GLY G 1 167 ? 21.213  35.270  53.095  1.00 29.11  ? 167 GLY G N   1 
ATOM   20271 C CA  . GLY G 1 167 ? 19.876  35.795  52.966  1.00 28.34  ? 167 GLY G CA  1 
ATOM   20272 C C   . GLY G 1 167 ? 19.250  35.485  51.625  1.00 28.23  ? 167 GLY G C   1 
ATOM   20273 O O   . GLY G 1 167 ? 19.914  34.997  50.702  1.00 25.51  ? 167 GLY G O   1 
ATOM   20274 N N   . PRO G 1 168 ? 17.950  35.791  51.490  1.00 29.48  ? 168 PRO G N   1 
ATOM   20275 C CA  . PRO G 1 168 ? 17.268  35.539  50.210  1.00 30.39  ? 168 PRO G CA  1 
ATOM   20276 C C   . PRO G 1 168 ? 17.963  36.215  49.052  1.00 28.15  ? 168 PRO G C   1 
ATOM   20277 O O   . PRO G 1 168 ? 18.086  35.624  47.972  1.00 29.07  ? 168 PRO G O   1 
ATOM   20278 C CB  . PRO G 1 168 ? 15.854  36.120  50.420  1.00 28.19  ? 168 PRO G CB  1 
ATOM   20279 C CG  . PRO G 1 168 ? 15.729  36.431  51.855  1.00 27.25  ? 168 PRO G CG  1 
ATOM   20280 C CD  . PRO G 1 168 ? 17.110  36.545  52.439  1.00 33.69  ? 168 PRO G CD  1 
ATOM   20281 N N   . ALA G 1 169 ? 18.426  37.450  49.246  1.00 31.93  ? 169 ALA G N   1 
ATOM   20282 C CA  . ALA G 1 169 ? 19.181  38.112  48.188  1.00 30.43  ? 169 ALA G CA  1 
ATOM   20283 C C   . ALA G 1 169 ? 20.401  37.281  47.798  1.00 33.31  ? 169 ALA G C   1 
ATOM   20284 O O   . ALA G 1 169 ? 20.666  37.064  46.608  1.00 33.91  ? 169 ALA G O   1 
ATOM   20285 C CB  . ALA G 1 169 ? 19.583  39.528  48.624  1.00 27.43  ? 169 ALA G CB  1 
ATOM   20286 N N   . GLU G 1 170 ? 21.142  36.762  48.785  1.00 31.29  ? 170 GLU G N   1 
ATOM   20287 C CA  . GLU G 1 170 ? 22.314  35.980  48.410  1.00 27.42  ? 170 GLU G CA  1 
ATOM   20288 C C   . GLU G 1 170 ? 21.921  34.630  47.814  1.00 27.70  ? 170 GLU G C   1 
ATOM   20289 O O   . GLU G 1 170 ? 22.603  34.124  46.912  1.00 26.57  ? 170 GLU G O   1 
ATOM   20290 C CB  . GLU G 1 170 ? 23.266  35.805  49.596  1.00 24.67  ? 170 GLU G CB  1 
ATOM   20291 C CG  . GLU G 1 170 ? 24.670  35.412  49.109  1.00 26.77  ? 170 GLU G CG  1 
ATOM   20292 C CD  . GLU G 1 170 ? 25.796  35.544  50.161  1.00 31.07  ? 170 GLU G CD  1 
ATOM   20293 O OE1 . GLU G 1 170 ? 25.535  35.469  51.389  1.00 25.84  ? 170 GLU G OE1 1 
ATOM   20294 O OE2 . GLU G 1 170 ? 26.966  35.699  49.731  1.00 27.39  ? 170 GLU G OE2 1 
ATOM   20295 N N   . VAL G 1 171 ? 20.814  34.048  48.262  1.00 27.63  ? 171 VAL G N   1 
ATOM   20296 C CA  . VAL G 1 171 ? 20.358  32.810  47.639  1.00 30.19  ? 171 VAL G CA  1 
ATOM   20297 C C   . VAL G 1 171 ? 19.976  33.055  46.187  1.00 31.36  ? 171 VAL G C   1 
ATOM   20298 O O   . VAL G 1 171 ? 20.177  32.192  45.327  1.00 27.95  ? 171 VAL G O   1 
ATOM   20299 C CB  . VAL G 1 171 ? 19.189  32.211  48.430  1.00 34.29  ? 171 VAL G CB  1 
ATOM   20300 C CG1 . VAL G 1 171 ? 18.587  31.010  47.672  1.00 32.19  ? 171 VAL G CG1 1 
ATOM   20301 C CG2 . VAL G 1 171 ? 19.660  31.816  49.804  1.00 26.54  ? 171 VAL G CG2 1 
ATOM   20302 N N   . ARG G 1 172 ? 19.434  34.241  45.889  1.00 28.78  ? 172 ARG G N   1 
ATOM   20303 C CA  . ARG G 1 172 ? 19.055  34.565  44.518  1.00 32.21  ? 172 ARG G CA  1 
ATOM   20304 C C   . ARG G 1 172 ? 20.280  34.735  43.626  1.00 32.48  ? 172 ARG G C   1 
ATOM   20305 O O   . ARG G 1 172 ? 20.335  34.190  42.517  1.00 32.10  ? 172 ARG G O   1 
ATOM   20306 C CB  . ARG G 1 172 ? 18.210  35.838  44.497  1.00 37.16  ? 172 ARG G CB  1 
ATOM   20307 C CG  . ARG G 1 172 ? 17.566  36.104  43.158  1.00 41.55  ? 172 ARG G CG  1 
ATOM   20308 C CD  . ARG G 1 172 ? 16.592  37.278  43.232  1.00 43.53  ? 172 ARG G CD  1 
ATOM   20309 N NE  . ARG G 1 172 ? 16.350  37.866  41.919  1.00 45.03  ? 172 ARG G NE  1 
ATOM   20310 C CZ  . ARG G 1 172 ? 17.287  38.369  41.130  1.00 45.89  ? 172 ARG G CZ  1 
ATOM   20311 N NH1 . ARG G 1 172 ? 18.552  38.445  41.517  1.00 52.28  ? 172 ARG G NH1 1 
ATOM   20312 N NH2 . ARG G 1 172 ? 16.944  38.821  39.926  1.00 54.83  ? 172 ARG G NH2 1 
ATOM   20313 N N   . SER G 1 173 ? 21.253  35.529  44.082  1.00 29.30  ? 173 SER G N   1 
ATOM   20314 C CA  . SER G 1 173 ? 22.530  35.640  43.379  1.00 36.17  ? 173 SER G CA  1 
ATOM   20315 C C   . SER G 1 173 ? 23.179  34.281  43.184  1.00 32.31  ? 173 SER G C   1 
ATOM   20316 O O   . SER G 1 173 ? 23.745  33.996  42.124  1.00 37.15  ? 173 SER G O   1 
ATOM   20317 C CB  . SER G 1 173 ? 23.473  36.557  44.155  1.00 34.22  ? 173 SER G CB  1 
ATOM   20318 O OG  . SER G 1 173 ? 23.392  37.878  43.652  1.00 49.06  ? 173 SER G OG  1 
ATOM   20319 N N   . ALA G 1 174 ? 23.126  33.434  44.209  1.00 31.20  ? 174 ALA G N   1 
ATOM   20320 C CA  . ALA G 1 174 ? 23.807  32.147  44.140  1.00 28.09  ? 174 ALA G CA  1 
ATOM   20321 C C   . ALA G 1 174 ? 23.189  31.236  43.080  1.00 28.94  ? 174 ALA G C   1 
ATOM   20322 O O   . ALA G 1 174 ? 23.904  30.642  42.267  1.00 33.50  ? 174 ALA G O   1 
ATOM   20323 C CB  . ALA G 1 174 ? 23.758  31.496  45.506  1.00 25.32  ? 174 ALA G CB  1 
ATOM   20324 N N   . ILE G 1 175 ? 21.858  31.106  43.077  1.00 32.43  ? 175 ILE G N   1 
ATOM   20325 C CA  . ILE G 1 175 ? 21.200  30.248  42.092  1.00 34.48  ? 175 ILE G CA  1 
ATOM   20326 C C   . ILE G 1 175 ? 21.575  30.671  40.678  1.00 31.11  ? 175 ILE G C   1 
ATOM   20327 O O   . ILE G 1 175 ? 21.897  29.838  39.828  1.00 35.76  ? 175 ILE G O   1 
ATOM   20328 C CB  . ILE G 1 175 ? 19.675  30.274  42.272  1.00 31.19  ? 175 ILE G CB  1 
ATOM   20329 C CG1 . ILE G 1 175 ? 19.271  29.742  43.637  1.00 32.00  ? 175 ILE G CG1 1 
ATOM   20330 C CG2 . ILE G 1 175 ? 19.017  29.465  41.165  1.00 33.29  ? 175 ILE G CG2 1 
ATOM   20331 C CD1 . ILE G 1 175 ? 17.924  30.195  44.028  1.00 25.79  ? 175 ILE G CD1 1 
ATOM   20332 N N   . GLN G 1 176 ? 21.522  31.973  40.401  1.00 31.57  ? 176 GLN G N   1 
ATOM   20333 C CA  . GLN G 1 176 ? 21.793  32.438  39.045  1.00 40.94  ? 176 GLN G CA  1 
ATOM   20334 C C   . GLN G 1 176 ? 23.249  32.188  38.663  1.00 35.46  ? 176 GLN G C   1 
ATOM   20335 O O   . GLN G 1 176 ? 23.540  31.752  37.544  1.00 37.30  ? 176 GLN G O   1 
ATOM   20336 C CB  . GLN G 1 176 ? 21.426  33.922  38.918  1.00 40.82  ? 176 GLN G CB  1 
ATOM   20337 C CG  . GLN G 1 176 ? 20.918  34.316  37.527  1.00 46.66  ? 176 GLN G CG  1 
ATOM   20338 C CD  . GLN G 1 176 ? 20.257  35.699  37.488  1.00 52.54  ? 176 GLN G CD  1 
ATOM   20339 O OE1 . GLN G 1 176 ? 20.239  36.425  38.482  1.00 50.79  ? 176 GLN G OE1 1 
ATOM   20340 N NE2 . GLN G 1 176 ? 19.721  36.065  36.327  1.00 56.96  ? 176 GLN G NE2 1 
ATOM   20341 N N   . GLU G 1 177 ? 24.177  32.432  39.586  1.00 36.12  ? 177 GLU G N   1 
ATOM   20342 C CA  . GLU G 1 177 ? 25.574  32.100  39.323  1.00 36.73  ? 177 GLU G CA  1 
ATOM   20343 C C   . GLU G 1 177 ? 25.733  30.607  39.045  1.00 36.24  ? 177 GLU G C   1 
ATOM   20344 O O   . GLU G 1 177 ? 26.265  30.213  38.003  1.00 41.63  ? 177 GLU G O   1 
ATOM   20345 C CB  . GLU G 1 177 ? 26.445  32.525  40.514  1.00 39.88  ? 177 GLU G CB  1 
ATOM   20346 C CG  . GLU G 1 177 ? 26.965  33.973  40.488  1.00 45.46  ? 177 GLU G CG  1 
ATOM   20347 C CD  . GLU G 1 177 ? 27.285  34.530  41.888  1.00 50.14  ? 177 GLU G CD  1 
ATOM   20348 O OE1 . GLU G 1 177 ? 27.112  33.803  42.889  1.00 44.81  ? 177 GLU G OE1 1 
ATOM   20349 O OE2 . GLU G 1 177 ? 27.710  35.702  41.992  1.00 49.38  ? 177 GLU G OE2 1 
ATOM   20350 N N   . LEU G 1 178 ? 25.227  29.761  39.946  1.00 35.51  ? 178 LEU G N   1 
ATOM   20351 C CA  . LEU G 1 178 ? 25.562  28.340  39.969  1.00 31.45  ? 178 LEU G CA  1 
ATOM   20352 C C   . LEU G 1 178 ? 24.666  27.466  39.103  1.00 33.12  ? 178 LEU G C   1 
ATOM   20353 O O   . LEU G 1 178 ? 24.941  26.271  38.981  1.00 31.72  ? 178 LEU G O   1 
ATOM   20354 C CB  . LEU G 1 178 ? 25.510  27.810  41.406  1.00 29.14  ? 178 LEU G CB  1 
ATOM   20355 C CG  . LEU G 1 178 ? 26.372  28.558  42.421  1.00 33.12  ? 178 LEU G CG  1 
ATOM   20356 C CD1 . LEU G 1 178 ? 25.848  28.375  43.836  1.00 23.76  ? 178 LEU G CD1 1 
ATOM   20357 C CD2 . LEU G 1 178 ? 27.821  28.097  42.305  1.00 29.55  ? 178 LEU G CD2 1 
ATOM   20358 N N   . ILE G 1 179 ? 23.597  28.005  38.515  1.00 33.95  ? 179 ILE G N   1 
ATOM   20359 C CA  . ILE G 1 179 ? 22.731  27.152  37.705  1.00 38.65  ? 179 ILE G CA  1 
ATOM   20360 C C   . ILE G 1 179 ? 23.344  26.857  36.341  1.00 40.26  ? 179 ILE G C   1 
ATOM   20361 O O   . ILE G 1 179 ? 23.018  25.829  35.733  1.00 41.49  ? 179 ILE G O   1 
ATOM   20362 C CB  . ILE G 1 179 ? 21.325  27.768  37.552  1.00 38.61  ? 179 ILE G CB  1 
ATOM   20363 C CG1 . ILE G 1 179 ? 20.356  26.770  36.917  1.00 39.21  ? 179 ILE G CG1 1 
ATOM   20364 C CG2 . ILE G 1 179 ? 21.372  29.045  36.739  1.00 40.32  ? 179 ILE G CG2 1 
ATOM   20365 C CD1 . ILE G 1 179 ? 19.937  25.638  37.833  1.00 39.10  ? 179 ILE G CD1 1 
ATOM   20366 N N   . ALA G 1 180 ? 24.255  27.704  35.858  1.00 39.99  ? 180 ALA G N   1 
ATOM   20367 C CA  . ALA G 1 180 ? 24.763  27.550  34.503  1.00 37.56  ? 180 ALA G CA  1 
ATOM   20368 C C   . ALA G 1 180 ? 25.728  26.382  34.348  1.00 43.94  ? 180 ALA G C   1 
ATOM   20369 O O   . ALA G 1 180 ? 25.969  25.948  33.217  1.00 43.53  ? 180 ALA G O   1 
ATOM   20370 C CB  . ALA G 1 180 ? 25.446  28.837  34.047  1.00 33.75  ? 180 ALA G CB  1 
ATOM   20371 N N   . GLU G 1 181 ? 26.289  25.852  35.437  1.00 39.32  ? 181 GLU G N   1 
ATOM   20372 C CA  . GLU G 1 181 ? 27.306  24.816  35.269  1.00 41.54  ? 181 GLU G CA  1 
ATOM   20373 C C   . GLU G 1 181 ? 26.695  23.504  34.778  1.00 40.51  ? 181 GLU G C   1 
ATOM   20374 O O   . GLU G 1 181 ? 27.170  22.916  33.804  1.00 41.43  ? 181 GLU G O   1 
ATOM   20375 C CB  . GLU G 1 181 ? 28.080  24.586  36.570  1.00 37.18  ? 181 GLU G CB  1 
ATOM   20376 C CG  . GLU G 1 181 ? 29.051  23.411  36.449  1.00 39.38  ? 181 GLU G CG  1 
ATOM   20377 C CD  . GLU G 1 181 ? 30.186  23.453  37.462  1.00 42.13  ? 181 GLU G CD  1 
ATOM   20378 O OE1 . GLU G 1 181 ? 30.057  24.153  38.494  1.00 37.09  ? 181 GLU G OE1 1 
ATOM   20379 O OE2 . GLU G 1 181 ? 31.207  22.769  37.219  1.00 45.88  ? 181 GLU G OE2 1 
ATOM   20380 N N   . THR G 1 182 ? 25.651  23.018  35.452  1.00 42.62  ? 182 THR G N   1 
ATOM   20381 C CA  . THR G 1 182 ? 25.016  21.762  35.079  1.00 37.35  ? 182 THR G CA  1 
ATOM   20382 C C   . THR G 1 182 ? 23.518  21.894  34.875  1.00 34.66  ? 182 THR G C   1 
ATOM   20383 O O   . THR G 1 182 ? 22.869  20.891  34.554  1.00 35.71  ? 182 THR G O   1 
ATOM   20384 C CB  . THR G 1 182 ? 25.269  20.686  36.145  1.00 33.18  ? 182 THR G CB  1 
ATOM   20385 O OG1 . THR G 1 182 ? 24.671  21.102  37.380  1.00 33.21  ? 182 THR G OG1 1 
ATOM   20386 C CG2 . THR G 1 182 ? 26.762  20.471  36.355  1.00 30.83  ? 182 THR G CG2 1 
ATOM   20387 N N   . GLY G 1 183 ? 22.952  23.090  35.045  1.00 34.59  ? 183 GLY G N   1 
ATOM   20388 C CA  . GLY G 1 183 ? 21.512  23.263  35.014  1.00 34.63  ? 183 GLY G CA  1 
ATOM   20389 C C   . GLY G 1 183 ? 20.813  22.717  36.235  1.00 40.43  ? 183 GLY G C   1 
ATOM   20390 O O   . GLY G 1 183 ? 19.576  22.697  36.287  1.00 38.79  ? 183 GLY G O   1 
ATOM   20391 N N   . MET G 1 184 ? 21.580  22.259  37.218  1.00 34.30  ? 184 MET G N   1 
ATOM   20392 C CA  . MET G 1 184 ? 21.043  21.724  38.451  1.00 36.33  ? 184 MET G CA  1 
ATOM   20393 C C   . MET G 1 184 ? 21.761  22.369  39.623  1.00 33.65  ? 184 MET G C   1 
ATOM   20394 O O   . MET G 1 184 ? 22.982  22.551  39.597  1.00 33.17  ? 184 MET G O   1 
ATOM   20395 C CB  . MET G 1 184 ? 21.204  20.212  38.512  1.00 35.32  ? 184 MET G CB  1 
ATOM   20396 C CG  . MET G 1 184 ? 20.449  19.486  37.441  1.00 38.13  ? 184 MET G CG  1 
ATOM   20397 S SD  . MET G 1 184 ? 20.552  17.732  37.740  1.00 41.45  ? 184 MET G SD  1 
ATOM   20398 C CE  . MET G 1 184 ? 22.124  17.361  36.966  1.00 42.41  ? 184 MET G CE  1 
ATOM   20399 N N   . VAL G 1 185 ? 20.991  22.695  40.652  1.00 29.14  ? 185 VAL G N   1 
ATOM   20400 C CA  . VAL G 1 185 ? 21.498  23.294  41.873  1.00 32.04  ? 185 VAL G CA  1 
ATOM   20401 C C   . VAL G 1 185 ? 20.789  22.623  43.043  1.00 36.23  ? 185 VAL G C   1 
ATOM   20402 O O   . VAL G 1 185 ? 19.607  22.269  42.947  1.00 30.47  ? 185 VAL G O   1 
ATOM   20403 C CB  . VAL G 1 185 ? 21.288  24.825  41.863  1.00 26.52  ? 185 VAL G CB  1 
ATOM   20404 C CG1 . VAL G 1 185 ? 21.413  25.406  43.250  1.00 35.01  ? 185 VAL G CG1 1 
ATOM   20405 C CG2 . VAL G 1 185 ? 22.290  25.487  40.935  1.00 28.00  ? 185 VAL G CG2 1 
ATOM   20406 N N   . ILE G 1 186 ? 21.511  22.420  44.144  1.00 27.37  ? 186 ILE G N   1 
ATOM   20407 C CA  . ILE G 1 186 ? 20.901  21.903  45.355  1.00 26.58  ? 186 ILE G CA  1 
ATOM   20408 C C   . ILE G 1 186 ? 21.029  22.963  46.440  1.00 30.23  ? 186 ILE G C   1 
ATOM   20409 O O   . ILE G 1 186 ? 22.056  23.640  46.543  1.00 28.71  ? 186 ILE G O   1 
ATOM   20410 C CB  . ILE G 1 186 ? 21.523  20.552  45.776  1.00 27.64  ? 186 ILE G CB  1 
ATOM   20411 C CG1 . ILE G 1 186 ? 20.776  19.971  46.973  1.00 29.07  ? 186 ILE G CG1 1 
ATOM   20412 C CG2 . ILE G 1 186 ? 23.020  20.679  46.077  1.00 29.05  ? 186 ILE G CG2 1 
ATOM   20413 C CD1 . ILE G 1 186 ? 20.881  18.474  47.070  1.00 27.61  ? 186 ILE G CD1 1 
ATOM   20414 N N   . ALA G 1 187 ? 19.956  23.144  47.210  1.00 29.61  ? 187 ALA G N   1 
ATOM   20415 C CA  . ALA G 1 187 ? 19.919  24.046  48.353  1.00 29.05  ? 187 ALA G CA  1 
ATOM   20416 C C   . ALA G 1 187 ? 19.642  23.231  49.611  1.00 30.97  ? 187 ALA G C   1 
ATOM   20417 O O   . ALA G 1 187 ? 18.710  22.423  49.629  1.00 32.25  ? 187 ALA G O   1 
ATOM   20418 C CB  . ALA G 1 187 ? 18.845  25.113  48.152  1.00 26.37  ? 187 ALA G CB  1 
ATOM   20419 N N   . LYS G 1 188 ? 20.445  23.431  50.654  1.00 24.17  ? 188 LYS G N   1 
ATOM   20420 C CA  . LYS G 1 188 ? 20.424  22.551  51.817  1.00 29.88  ? 188 LYS G CA  1 
ATOM   20421 C C   . LYS G 1 188 ? 20.211  23.342  53.100  1.00 33.27  ? 188 LYS G C   1 
ATOM   20422 O O   . LYS G 1 188 ? 20.684  24.475  53.238  1.00 33.48  ? 188 LYS G O   1 
ATOM   20423 C CB  . LYS G 1 188 ? 21.741  21.743  51.964  1.00 34.66  ? 188 LYS G CB  1 
ATOM   20424 C CG  . LYS G 1 188 ? 22.123  20.871  50.774  1.00 37.76  ? 188 LYS G CG  1 
ATOM   20425 C CD  . LYS G 1 188 ? 23.548  20.351  50.909  1.00 34.48  ? 188 LYS G CD  1 
ATOM   20426 C CE  . LYS G 1 188 ? 23.643  18.855  50.722  1.00 42.84  ? 188 LYS G CE  1 
ATOM   20427 N NZ  . LYS G 1 188 ? 24.979  18.315  51.129  1.00 37.87  ? 188 LYS G NZ  1 
ATOM   20428 N N   . GLN G 1 189 ? 19.497  22.721  54.040  1.00 35.23  ? 189 GLN G N   1 
ATOM   20429 C CA  . GLN G 1 189 ? 19.481  23.178  55.426  1.00 37.40  ? 189 GLN G CA  1 
ATOM   20430 C C   . GLN G 1 189 ? 20.878  23.084  56.020  1.00 30.93  ? 189 GLN G C   1 
ATOM   20431 O O   . GLN G 1 189 ? 21.601  22.122  55.769  1.00 31.96  ? 189 GLN G O   1 
ATOM   20432 C CB  . GLN G 1 189 ? 18.528  22.310  56.239  1.00 37.95  ? 189 GLN G CB  1 
ATOM   20433 C CG  . GLN G 1 189 ? 18.216  22.833  57.603  1.00 48.79  ? 189 GLN G CG  1 
ATOM   20434 C CD  . GLN G 1 189 ? 16.911  22.272  58.134  1.00 61.52  ? 189 GLN G CD  1 
ATOM   20435 O OE1 . GLN G 1 189 ? 16.129  21.662  57.389  1.00 59.19  ? 189 GLN G OE1 1 
ATOM   20436 N NE2 . GLN G 1 189 ? 16.667  22.472  59.428  1.00 55.19  ? 189 GLN G NE2 1 
ATOM   20437 N N   . ASP G 1 190 ? 21.265  24.072  56.830  1.00 29.53  ? 190 ASP G N   1 
ATOM   20438 C CA  . ASP G 1 190 ? 22.651  24.078  57.304  1.00 33.25  ? 190 ASP G CA  1 
ATOM   20439 C C   . ASP G 1 190 ? 22.955  22.950  58.293  1.00 37.65  ? 190 ASP G C   1 
ATOM   20440 O O   . ASP G 1 190 ? 24.083  22.428  58.298  1.00 31.47  ? 190 ASP G O   1 
ATOM   20441 C CB  . ASP G 1 190 ? 23.021  25.413  57.933  1.00 29.14  ? 190 ASP G CB  1 
ATOM   20442 C CG  . ASP G 1 190 ? 24.523  25.635  57.923  1.00 28.70  ? 190 ASP G CG  1 
ATOM   20443 O OD1 . ASP G 1 190 ? 25.175  24.998  57.073  1.00 31.41  ? 190 ASP G OD1 1 
ATOM   20444 O OD2 . ASP G 1 190 ? 25.068  26.397  58.753  1.00 31.49  ? 190 ASP G OD2 1 
ATOM   20445 N N   . ARG G 1 191 ? 21.991  22.557  59.136  1.00 42.48  ? 191 ARG G N   1 
ATOM   20446 C CA  . ARG G 1 191 ? 22.256  21.571  60.184  1.00 45.81  ? 191 ARG G CA  1 
ATOM   20447 C C   . ARG G 1 191 ? 21.669  20.196  59.883  1.00 56.93  ? 191 ARG G C   1 
ATOM   20448 O O   . ARG G 1 191 ? 22.419  19.215  59.791  1.00 60.27  ? 191 ARG G O   1 
ATOM   20449 C CB  . ARG G 1 191 ? 21.741  22.067  61.544  1.00 43.33  ? 191 ARG G CB  1 
ATOM   20450 C CG  . ARG G 1 191 ? 22.637  23.097  62.225  1.00 44.51  ? 191 ARG G CG  1 
ATOM   20451 C CD  . ARG G 1 191 ? 23.196  22.653  63.574  1.00 50.43  ? 191 ARG G CD  1 
ATOM   20452 N NE  . ARG G 1 191 ? 24.008  23.712  64.166  1.00 51.10  ? 191 ARG G NE  1 
ATOM   20453 C CZ  . ARG G 1 191 ? 23.710  24.352  65.290  1.00 56.08  ? 191 ARG G CZ  1 
ATOM   20454 N NH1 . ARG G 1 191 ? 22.674  23.997  66.034  1.00 57.32  ? 191 ARG G NH1 1 
ATOM   20455 N NH2 . ARG G 1 191 ? 24.476  25.371  65.684  1.00 44.33  ? 191 ARG G NH2 1 
ATOM   20456 N N   . SER G 1 192 ? 20.347  20.085  59.749  1.00 60.19  ? 192 SER G N   1 
ATOM   20457 C CA  . SER G 1 192 ? 19.714  18.768  59.816  1.00 75.96  ? 192 SER G CA  1 
ATOM   20458 C C   . SER G 1 192 ? 20.249  17.830  58.738  1.00 79.57  ? 192 SER G C   1 
ATOM   20459 O O   . SER G 1 192 ? 20.536  18.244  57.608  1.00 74.57  ? 192 SER G O   1 
ATOM   20460 C CB  . SER G 1 192 ? 18.191  18.882  59.685  1.00 77.13  ? 192 SER G CB  1 
ATOM   20461 O OG  . SER G 1 192 ? 17.774  18.806  58.327  1.00 78.87  ? 192 SER G OG  1 
ATOM   20462 N N   . GLY G 1 193 ? 20.398  16.566  59.105  1.00 82.19  ? 193 GLY G N   1 
ATOM   20463 C CA  . GLY G 1 193 ? 20.655  15.481  58.172  1.00 80.67  ? 193 GLY G CA  1 
ATOM   20464 C C   . GLY G 1 193 ? 19.366  14.823  57.728  1.00 87.58  ? 193 GLY G C   1 
ATOM   20465 O O   . GLY G 1 193 ? 18.336  15.484  57.554  1.00 87.11  ? 193 GLY G O   1 
ATOM   20466 N N   . GLY G 1 194 ? 19.417  13.501  57.555  1.00 91.67  ? 194 GLY G N   1 
ATOM   20467 C CA  . GLY G 1 194 ? 18.237  12.733  57.196  1.00 97.56  ? 194 GLY G CA  1 
ATOM   20468 C C   . GLY G 1 194 ? 17.666  13.121  55.838  1.00 96.87  ? 194 GLY G C   1 
ATOM   20469 O O   . GLY G 1 194 ? 18.303  13.786  55.021  1.00 94.77  ? 194 GLY G O   1 
ATOM   20470 N N   . GLY G 1 195 ? 16.422  12.696  55.617  1.00 97.11  ? 195 GLY G N   1 
ATOM   20471 C CA  . GLY G 1 195 ? 15.762  12.922  54.346  1.00 94.03  ? 195 GLY G CA  1 
ATOM   20472 C C   . GLY G 1 195 ? 14.671  13.975  54.372  1.00 99.59  ? 195 GLY G C   1 
ATOM   20473 O O   . GLY G 1 195 ? 13.652  13.834  53.687  1.00 99.64  ? 195 GLY G O   1 
ATOM   20474 N N   . HIS G 1 196 ? 14.869  15.040  55.152  1.00 100.12 ? 196 HIS G N   1 
ATOM   20475 C CA  . HIS G 1 196 ? 13.916  16.152  55.229  1.00 96.97  ? 196 HIS G CA  1 
ATOM   20476 C C   . HIS G 1 196 ? 14.728  17.438  55.372  1.00 90.35  ? 196 HIS G C   1 
ATOM   20477 O O   . HIS G 1 196 ? 15.153  17.781  56.481  1.00 88.38  ? 196 HIS G O   1 
ATOM   20478 C CB  . HIS G 1 196 ? 12.944  15.984  56.399  1.00 97.66  ? 196 HIS G CB  1 
ATOM   20479 C CG  . HIS G 1 196 ? 11.827  15.013  56.142  1.00 99.93  ? 196 HIS G CG  1 
ATOM   20480 N ND1 . HIS G 1 196 ? 10.559  15.415  55.779  1.00 101.32 ? 196 HIS G ND1 1 
ATOM   20481 C CD2 . HIS G 1 196 ? 11.784  13.661  56.220  1.00 100.52 ? 196 HIS G CD2 1 
ATOM   20482 C CE1 . HIS G 1 196 ? 9.787   14.353  55.631  1.00 96.29  ? 196 HIS G CE1 1 
ATOM   20483 N NE2 . HIS G 1 196 ? 10.506  13.276  55.892  1.00 100.54 ? 196 HIS G NE2 1 
ATOM   20484 N N   . GLY G 1 197 ? 14.955  18.139  54.256  1.00 82.85  ? 197 GLY G N   1 
ATOM   20485 C CA  . GLY G 1 197 ? 15.594  19.445  54.324  1.00 68.90  ? 197 GLY G CA  1 
ATOM   20486 C C   . GLY G 1 197 ? 16.629  19.791  53.267  1.00 51.95  ? 197 GLY G C   1 
ATOM   20487 O O   . GLY G 1 197 ? 17.553  20.567  53.545  1.00 46.83  ? 197 GLY G O   1 
ATOM   20488 N N   . ASN G 1 198 ? 16.497  19.227  52.063  1.00 46.08  ? 198 ASN G N   1 
ATOM   20489 C CA  . ASN G 1 198 ? 17.292  19.615  50.901  1.00 40.47  ? 198 ASN G CA  1 
ATOM   20490 C C   . ASN G 1 198 ? 16.350  19.829  49.726  1.00 43.60  ? 198 ASN G C   1 
ATOM   20491 O O   . ASN G 1 198 ? 15.438  19.028  49.505  1.00 44.60  ? 198 ASN G O   1 
ATOM   20492 C CB  . ASN G 1 198 ? 18.337  18.552  50.517  1.00 42.81  ? 198 ASN G CB  1 
ATOM   20493 C CG  . ASN G 1 198 ? 19.531  18.529  51.453  1.00 47.29  ? 198 ASN G CG  1 
ATOM   20494 O OD1 . ASN G 1 198 ? 19.719  19.444  52.254  1.00 44.50  ? 198 ASN G OD1 1 
ATOM   20495 N ND2 . ASN G 1 198 ? 20.333  17.458  51.375  1.00 39.43  ? 198 ASN G ND2 1 
ATOM   20496 N N   . ILE G 1 199 ? 16.568  20.895  48.964  1.00 37.52  ? 199 ILE G N   1 
ATOM   20497 C CA  . ILE G 1 199 ? 15.693  21.224  47.849  1.00 37.22  ? 199 ILE G CA  1 
ATOM   20498 C C   . ILE G 1 199 ? 16.523  21.381  46.588  1.00 35.81  ? 199 ILE G C   1 
ATOM   20499 O O   . ILE G 1 199 ? 17.505  22.130  46.573  1.00 34.15  ? 199 ILE G O   1 
ATOM   20500 C CB  . ILE G 1 199 ? 14.875  22.496  48.122  1.00 33.10  ? 199 ILE G CB  1 
ATOM   20501 C CG1 . ILE G 1 199 ? 14.012  22.292  49.359  1.00 31.92  ? 199 ILE G CG1 1 
ATOM   20502 C CG2 . ILE G 1 199 ? 14.023  22.819  46.926  1.00 31.18  ? 199 ILE G CG2 1 
ATOM   20503 C CD1 . ILE G 1 199 ? 13.436  23.570  49.912  1.00 32.77  ? 199 ILE G CD1 1 
ATOM   20504 N N   . GLY G 1 200 ? 16.133  20.668  45.536  1.00 38.29  ? 200 GLY G N   1 
ATOM   20505 C CA  . GLY G 1 200 ? 16.786  20.804  44.260  1.00 36.24  ? 200 GLY G CA  1 
ATOM   20506 C C   . GLY G 1 200 ? 16.109  21.838  43.382  1.00 39.80  ? 200 GLY G C   1 
ATOM   20507 O O   . GLY G 1 200 ? 14.943  22.180  43.570  1.00 40.46  ? 200 GLY G O   1 
ATOM   20508 N N   . ILE G 1 201 ? 16.882  22.340  42.429  1.00 34.68  ? 201 ILE G N   1 
ATOM   20509 C CA  . ILE G 1 201 ? 16.429  23.306  41.435  1.00 39.94  ? 201 ILE G CA  1 
ATOM   20510 C C   . ILE G 1 201 ? 16.987  22.855  40.099  1.00 37.40  ? 201 ILE G C   1 
ATOM   20511 O O   . ILE G 1 201 ? 18.192  22.616  39.978  1.00 33.80  ? 201 ILE G O   1 
ATOM   20512 C CB  . ILE G 1 201 ? 16.897  24.739  41.748  1.00 35.95  ? 201 ILE G CB  1 
ATOM   20513 C CG1 . ILE G 1 201 ? 16.159  25.294  42.960  1.00 40.26  ? 201 ILE G CG1 1 
ATOM   20514 C CG2 . ILE G 1 201 ? 16.684  25.644  40.538  1.00 41.94  ? 201 ILE G CG2 1 
ATOM   20515 C CD1 . ILE G 1 201 ? 16.361  26.765  43.142  1.00 37.97  ? 201 ILE G CD1 1 
ATOM   20516 N N   . SER G 1 202 ? 16.119  22.717  39.108  1.00 37.06  ? 202 SER G N   1 
ATOM   20517 C CA  . SER G 1 202 ? 16.506  22.164  37.824  1.00 38.65  ? 202 SER G CA  1 
ATOM   20518 C C   . SER G 1 202 ? 15.975  23.035  36.699  1.00 43.49  ? 202 SER G C   1 
ATOM   20519 O O   . SER G 1 202 ? 14.903  23.636  36.809  1.00 46.30  ? 202 SER G O   1 
ATOM   20520 C CB  . SER G 1 202 ? 15.990  20.748  37.653  1.00 40.30  ? 202 SER G CB  1 
ATOM   20521 O OG  . SER G 1 202 ? 16.202  20.300  36.328  1.00 48.33  ? 202 SER G OG  1 
ATOM   20522 N N   . THR G 1 203 ? 16.754  23.109  35.625  1.00 41.14  ? 203 THR G N   1 
ATOM   20523 C CA  . THR G 1 203 ? 16.301  23.718  34.388  1.00 45.14  ? 203 THR G CA  1 
ATOM   20524 C C   . THR G 1 203 ? 15.576  22.729  33.497  1.00 47.32  ? 203 THR G C   1 
ATOM   20525 O O   . THR G 1 203 ? 14.777  23.149  32.655  1.00 52.11  ? 203 THR G O   1 
ATOM   20526 C CB  . THR G 1 203 ? 17.483  24.291  33.603  1.00 45.01  ? 203 THR G CB  1 
ATOM   20527 O OG1 . THR G 1 203 ? 18.431  23.244  33.349  1.00 50.40  ? 203 THR G OG1 1 
ATOM   20528 C CG2 . THR G 1 203 ? 18.162  25.397  34.384  1.00 38.13  ? 203 THR G CG2 1 
ATOM   20529 N N   . SER G 1 204 ? 15.848  21.433  33.652  1.00 48.72  ? 204 SER G N   1 
ATOM   20530 C CA  . SER G 1 204 ? 15.237  20.406  32.818  1.00 55.40  ? 204 SER G CA  1 
ATOM   20531 C C   . SER G 1 204 ? 14.155  19.668  33.585  1.00 60.50  ? 204 SER G C   1 
ATOM   20532 O O   . SER G 1 204 ? 14.297  19.426  34.794  1.00 55.40  ? 204 SER G O   1 
ATOM   20533 C CB  . SER G 1 204 ? 16.274  19.390  32.328  1.00 54.33  ? 204 SER G CB  1 
ATOM   20534 O OG  . SER G 1 204 ? 15.684  18.414  31.478  1.00 53.99  ? 204 SER G OG  1 
ATOM   20535 N N   . PRO G 1 205 ? 13.076  19.310  32.895  1.00 62.71  ? 205 PRO G N   1 
ATOM   20536 C CA  . PRO G 1 205 ? 12.081  18.437  33.512  1.00 64.13  ? 205 PRO G CA  1 
ATOM   20537 C C   . PRO G 1 205 ? 12.717  17.102  33.858  1.00 65.58  ? 205 PRO G C   1 
ATOM   20538 O O   . PRO G 1 205 ? 13.729  16.696  33.280  1.00 65.77  ? 205 PRO G O   1 
ATOM   20539 C CB  . PRO G 1 205 ? 11.004  18.282  32.429  1.00 59.63  ? 205 PRO G CB  1 
ATOM   20540 C CG  . PRO G 1 205 ? 11.302  19.345  31.406  1.00 65.69  ? 205 PRO G CG  1 
ATOM   20541 C CD  . PRO G 1 205 ? 12.771  19.594  31.484  1.00 58.42  ? 205 PRO G CD  1 
ATOM   20542 N N   . GLU G 1 206 ? 12.120  16.441  34.841  1.00 70.59  ? 206 GLU G N   1 
ATOM   20543 C CA  . GLU G 1 206 ? 12.436  15.059  35.194  1.00 74.78  ? 206 GLU G CA  1 
ATOM   20544 C C   . GLU G 1 206 ? 13.938  14.799  35.217  1.00 72.90  ? 206 GLU G C   1 
ATOM   20545 O O   . GLU G 1 206 ? 14.445  13.848  34.617  1.00 75.83  ? 206 GLU G O   1 
ATOM   20546 C CB  . GLU G 1 206 ? 11.730  14.080  34.254  1.00 79.16  ? 206 GLU G CB  1 
ATOM   20547 C CG  . GLU G 1 206 ? 10.365  13.625  34.758  1.00 75.76  ? 206 GLU G CG  1 
ATOM   20548 C CD  . GLU G 1 206 ? 10.456  12.744  35.992  1.00 73.17  ? 206 GLU G CD  1 
ATOM   20549 O OE1 . GLU G 1 206 ? 11.564  12.258  36.311  1.00 71.91  ? 206 GLU G OE1 1 
ATOM   20550 O OE2 . GLU G 1 206 ? 9.415   12.543  36.650  1.00 77.02  ? 206 GLU G OE2 1 
ATOM   20551 N N   . SER G 1 207 ? 14.661  15.681  35.897  1.00 70.48  ? 207 SER G N   1 
ATOM   20552 C CA  . SER G 1 207 ? 15.980  15.336  36.402  1.00 71.40  ? 207 SER G CA  1 
ATOM   20553 C C   . SER G 1 207 ? 15.814  14.883  37.845  1.00 67.78  ? 207 SER G C   1 
ATOM   20554 O O   . SER G 1 207 ? 14.875  15.291  38.534  1.00 66.49  ? 207 SER G O   1 
ATOM   20555 C CB  . SER G 1 207 ? 16.965  16.504  36.298  1.00 60.90  ? 207 SER G CB  1 
ATOM   20556 O OG  . SER G 1 207 ? 16.477  17.660  36.947  1.00 66.44  ? 207 SER G OG  1 
ATOM   20557 N N   . SER G 1 208 ? 16.705  14.005  38.288  1.00 64.47  ? 208 SER G N   1 
ATOM   20558 C CA  . SER G 1 208 ? 16.503  13.279  39.533  1.00 61.49  ? 208 SER G CA  1 
ATOM   20559 C C   . SER G 1 208 ? 17.538  13.700  40.566  1.00 57.43  ? 208 SER G C   1 
ATOM   20560 O O   . SER G 1 208 ? 18.739  13.711  40.284  1.00 52.66  ? 208 SER G O   1 
ATOM   20561 C CB  . SER G 1 208 ? 16.555  11.773  39.282  1.00 66.29  ? 208 SER G CB  1 
ATOM   20562 O OG  . SER G 1 208 ? 15.691  11.428  38.213  1.00 67.33  ? 208 SER G OG  1 
ATOM   20563 N N   . PHE G 1 209 ? 17.059  14.043  41.763  1.00 59.01  ? 209 PHE G N   1 
ATOM   20564 C CA  . PHE G 1 209 ? 17.888  14.528  42.866  1.00 52.59  ? 209 PHE G CA  1 
ATOM   20565 C C   . PHE G 1 209 ? 17.727  13.594  44.058  1.00 53.35  ? 209 PHE G C   1 
ATOM   20566 O O   . PHE G 1 209 ? 16.861  13.829  44.916  1.00 57.32  ? 209 PHE G O   1 
ATOM   20567 C CB  . PHE G 1 209 ? 17.475  15.933  43.286  1.00 48.13  ? 209 PHE G CB  1 
ATOM   20568 C CG  . PHE G 1 209 ? 17.894  17.034  42.356  1.00 44.52  ? 209 PHE G CG  1 
ATOM   20569 C CD1 . PHE G 1 209 ? 17.158  17.329  41.226  1.00 48.78  ? 209 PHE G CD1 1 
ATOM   20570 C CD2 . PHE G 1 209 ? 18.968  17.844  42.674  1.00 43.83  ? 209 PHE G CD2 1 
ATOM   20571 C CE1 . PHE G 1 209 ? 17.515  18.385  40.401  1.00 48.58  ? 209 PHE G CE1 1 
ATOM   20572 C CE2 . PHE G 1 209 ? 19.331  18.895  41.861  1.00 39.17  ? 209 PHE G CE2 1 
ATOM   20573 C CZ  . PHE G 1 209 ? 18.600  19.170  40.721  1.00 42.08  ? 209 PHE G CZ  1 
ATOM   20574 N N   . PRO G 1 210 ? 18.517  12.527  44.159  1.00 55.71  ? 210 PRO G N   1 
ATOM   20575 C CA  . PRO G 1 210 ? 18.499  11.731  45.395  1.00 53.24  ? 210 PRO G CA  1 
ATOM   20576 C C   . PRO G 1 210 ? 18.951  12.565  46.586  1.00 52.68  ? 210 PRO G C   1 
ATOM   20577 O O   . PRO G 1 210 ? 19.877  13.373  46.490  1.00 56.61  ? 210 PRO G O   1 
ATOM   20578 C CB  . PRO G 1 210 ? 19.468  10.577  45.101  1.00 55.09  ? 210 PRO G CB  1 
ATOM   20579 C CG  . PRO G 1 210 ? 20.194  10.958  43.827  1.00 57.56  ? 210 PRO G CG  1 
ATOM   20580 C CD  . PRO G 1 210 ? 19.268  11.867  43.078  1.00 54.13  ? 210 PRO G CD  1 
ATOM   20581 N N   . GLY G 1 211 ? 18.263  12.381  47.715  1.00 54.54  ? 211 GLY G N   1 
ATOM   20582 C CA  . GLY G 1 211 ? 18.510  13.124  48.925  1.00 51.21  ? 211 GLY G CA  1 
ATOM   20583 C C   . GLY G 1 211 ? 17.592  14.313  49.125  1.00 55.51  ? 211 GLY G C   1 
ATOM   20584 O O   . GLY G 1 211 ? 17.297  14.668  50.272  1.00 56.05  ? 211 GLY G O   1 
ATOM   20585 N N   . THR G 1 212 ? 17.129  14.931  48.038  1.00 50.64  ? 212 THR G N   1 
ATOM   20586 C CA  . THR G 1 212 ? 16.263  16.093  48.133  1.00 50.69  ? 212 THR G CA  1 
ATOM   20587 C C   . THR G 1 212 ? 14.841  15.703  48.512  1.00 47.39  ? 212 THR G C   1 
ATOM   20588 O O   . THR G 1 212 ? 14.421  14.554  48.374  1.00 50.16  ? 212 THR G O   1 
ATOM   20589 C CB  . THR G 1 212 ? 16.244  16.865  46.813  1.00 50.29  ? 212 THR G CB  1 
ATOM   20590 O OG1 . THR G 1 212 ? 15.580  16.086  45.807  1.00 39.15  ? 212 THR G OG1 1 
ATOM   20591 C CG2 . THR G 1 212 ? 17.655  17.236  46.385  1.00 47.40  ? 212 THR G CG2 1 
ATOM   20592 N N   . ARG G 1 213 ? 14.097  16.697  48.989  1.00 47.46  ? 213 ARG G N   1 
ATOM   20593 C CA  . ARG G 1 213 ? 12.702  16.523  49.357  1.00 47.69  ? 213 ARG G CA  1 
ATOM   20594 C C   . ARG G 1 213 ? 11.748  16.924  48.244  1.00 50.72  ? 213 ARG G C   1 
ATOM   20595 O O   . ARG G 1 213 ? 10.599  16.470  48.238  1.00 49.13  ? 213 ARG G O   1 
ATOM   20596 C CB  . ARG G 1 213 ? 12.398  17.332  50.618  1.00 50.17  ? 213 ARG G CB  1 
ATOM   20597 C CG  . ARG G 1 213 ? 11.976  18.746  50.372  1.00 47.68  ? 213 ARG G CG  1 
ATOM   20598 C CD  . ARG G 1 213 ? 11.888  19.472  51.693  1.00 53.26  ? 213 ARG G CD  1 
ATOM   20599 N NE  . ARG G 1 213 ? 11.605  20.887  51.518  1.00 51.39  ? 213 ARG G NE  1 
ATOM   20600 C CZ  . ARG G 1 213 ? 10.887  21.609  52.366  1.00 51.45  ? 213 ARG G CZ  1 
ATOM   20601 N NH1 . ARG G 1 213 ? 10.430  21.094  53.497  1.00 49.89  ? 213 ARG G NH1 1 
ATOM   20602 N NH2 . ARG G 1 213 ? 10.606  22.872  52.064  1.00 56.20  ? 213 ARG G NH2 1 
ATOM   20603 N N   . GLU G 1 214 ? 12.203  17.754  47.312  1.00 46.56  ? 214 GLU G N   1 
ATOM   20604 C CA  . GLU G 1 214 ? 11.458  18.138  46.124  1.00 48.61  ? 214 GLU G CA  1 
ATOM   20605 C C   . GLU G 1 214 ? 12.403  18.914  45.226  1.00 50.73  ? 214 GLU G C   1 
ATOM   20606 O O   . GLU G 1 214 ? 13.454  19.394  45.668  1.00 46.13  ? 214 GLU G O   1 
ATOM   20607 C CB  . GLU G 1 214 ? 10.220  18.982  46.451  1.00 48.25  ? 214 GLU G CB  1 
ATOM   20608 C CG  . GLU G 1 214 ? 10.508  20.324  47.124  1.00 48.29  ? 214 GLU G CG  1 
ATOM   20609 C CD  . GLU G 1 214 ? 9.235   21.146  47.376  1.00 56.36  ? 214 GLU G CD  1 
ATOM   20610 O OE1 . GLU G 1 214 ? 8.170   20.807  46.801  1.00 54.61  ? 214 GLU G OE1 1 
ATOM   20611 O OE2 . GLU G 1 214 ? 9.301   22.133  48.146  1.00 49.20  ? 214 GLU G OE2 1 
ATOM   20612 N N   . VAL G 1 215 ? 12.014  19.036  43.961  1.00 48.81  ? 215 VAL G N   1 
ATOM   20613 C CA  . VAL G 1 215 ? 12.769  19.796  42.976  1.00 50.06  ? 215 VAL G CA  1 
ATOM   20614 C C   . VAL G 1 215 ? 11.866  20.892  42.429  1.00 45.52  ? 215 VAL G C   1 
ATOM   20615 O O   . VAL G 1 215 ? 10.717  20.628  42.056  1.00 50.29  ? 215 VAL G O   1 
ATOM   20616 C CB  . VAL G 1 215 ? 13.289  18.893  41.848  1.00 47.98  ? 215 VAL G CB  1 
ATOM   20617 C CG1 . VAL G 1 215 ? 14.029  19.724  40.810  1.00 41.12  ? 215 VAL G CG1 1 
ATOM   20618 C CG2 . VAL G 1 215 ? 14.161  17.794  42.438  1.00 51.16  ? 215 VAL G CG2 1 
ATOM   20619 N N   . LEU G 1 216 ? 12.378  22.117  42.401  1.00 43.64  ? 216 LEU G N   1 
ATOM   20620 C CA  . LEU G 1 216 ? 11.642  23.279  41.924  1.00 43.55  ? 216 LEU G CA  1 
ATOM   20621 C C   . LEU G 1 216 ? 12.251  23.727  40.606  1.00 44.12  ? 216 LEU G C   1 
ATOM   20622 O O   . LEU G 1 216 ? 13.467  23.914  40.518  1.00 44.87  ? 216 LEU G O   1 
ATOM   20623 C CB  . LEU G 1 216 ? 11.690  24.420  42.944  1.00 39.45  ? 216 LEU G CB  1 
ATOM   20624 C CG  . LEU G 1 216 ? 11.025  24.207  44.299  1.00 43.19  ? 216 LEU G CG  1 
ATOM   20625 C CD1 . LEU G 1 216 ? 11.158  25.458  45.170  1.00 40.06  ? 216 LEU G CD1 1 
ATOM   20626 C CD2 . LEU G 1 216 ? 9.574   23.822  44.116  1.00 41.27  ? 216 LEU G CD2 1 
ATOM   20627 N N   . ALA G 1 217 ? 11.413  23.902  39.589  1.00 42.73  ? 217 ALA G N   1 
ATOM   20628 C CA  . ALA G 1 217 ? 11.920  24.245  38.268  1.00 44.46  ? 217 ALA G CA  1 
ATOM   20629 C C   . ALA G 1 217 ? 12.469  25.667  38.237  1.00 44.31  ? 217 ALA G C   1 
ATOM   20630 O O   . ALA G 1 217 ? 11.971  26.569  38.915  1.00 45.25  ? 217 ALA G O   1 
ATOM   20631 C CB  . ALA G 1 217 ? 10.821  24.089  37.220  1.00 52.37  ? 217 ALA G CB  1 
ATOM   20632 N N   . TYR G 1 218 ? 13.500  25.862  37.422  1.00 46.53  ? 218 TYR G N   1 
ATOM   20633 C CA  . TYR G 1 218 ? 14.199  27.137  37.325  1.00 45.88  ? 218 TYR G CA  1 
ATOM   20634 C C   . TYR G 1 218 ? 13.627  27.970  36.185  1.00 48.78  ? 218 TYR G C   1 
ATOM   20635 O O   . TYR G 1 218 ? 13.488  27.479  35.059  1.00 48.76  ? 218 TYR G O   1 
ATOM   20636 C CB  . TYR G 1 218 ? 15.700  26.931  37.100  1.00 40.94  ? 218 TYR G CB  1 
ATOM   20637 C CG  . TYR G 1 218 ? 16.451  28.230  36.886  1.00 45.48  ? 218 TYR G CG  1 
ATOM   20638 C CD1 . TYR G 1 218 ? 16.802  29.028  37.961  1.00 39.46  ? 218 TYR G CD1 1 
ATOM   20639 C CD2 . TYR G 1 218 ? 16.796  28.660  35.610  1.00 43.93  ? 218 TYR G CD2 1 
ATOM   20640 C CE1 . TYR G 1 218 ? 17.477  30.213  37.780  1.00 44.29  ? 218 TYR G CE1 1 
ATOM   20641 C CE2 . TYR G 1 218 ? 17.471  29.846  35.419  1.00 47.39  ? 218 TYR G CE2 1 
ATOM   20642 C CZ  . TYR G 1 218 ? 17.806  30.621  36.513  1.00 50.48  ? 218 TYR G CZ  1 
ATOM   20643 O OH  . TYR G 1 218 ? 18.482  31.803  36.346  1.00 52.09  ? 218 TYR G OH  1 
ATOM   20644 N N   . ALA G 1 219 ? 13.310  29.228  36.484  1.00 49.92  ? 219 ALA G N   1 
ATOM   20645 C CA  . ALA G 1 219 ? 12.979  30.227  35.479  1.00 50.50  ? 219 ALA G CA  1 
ATOM   20646 C C   . ALA G 1 219 ? 13.461  31.575  35.989  1.00 48.06  ? 219 ALA G C   1 
ATOM   20647 O O   . ALA G 1 219 ? 13.333  31.876  37.179  1.00 51.47  ? 219 ALA G O   1 
ATOM   20648 C CB  . ALA G 1 219 ? 11.476  30.271  35.179  1.00 52.42  ? 219 ALA G CB  1 
ATOM   20649 N N   . ASN G 1 220 ? 14.021  32.376  35.079  1.00 50.18  ? 220 ASN G N   1 
ATOM   20650 C CA  . ASN G 1 220 ? 14.611  33.655  35.463  1.00 51.64  ? 220 ASN G CA  1 
ATOM   20651 C C   . ASN G 1 220 ? 13.579  34.577  36.114  1.00 51.65  ? 220 ASN G C   1 
ATOM   20652 O O   . ASN G 1 220 ? 13.901  35.306  37.061  1.00 48.82  ? 220 ASN G O   1 
ATOM   20653 C CB  . ASN G 1 220 ? 15.257  34.296  34.231  1.00 50.11  ? 220 ASN G CB  1 
ATOM   20654 C CG  . ASN G 1 220 ? 16.191  35.449  34.571  1.00 56.17  ? 220 ASN G CG  1 
ATOM   20655 O OD1 . ASN G 1 220 ? 15.847  36.360  35.333  1.00 53.86  ? 220 ASN G OD1 1 
ATOM   20656 N ND2 . ASN G 1 220 ? 17.400  35.399  34.014  1.00 62.92  ? 220 ASN G ND2 1 
ATOM   20657 N N   . ASP G 1 221 ? 12.324  34.533  35.650  1.00 52.62  ? 221 ASP G N   1 
ATOM   20658 C CA  . ASP G 1 221 ? 11.278  35.371  36.232  1.00 50.77  ? 221 ASP G CA  1 
ATOM   20659 C C   . ASP G 1 221 ? 10.758  34.848  37.561  1.00 50.14  ? 221 ASP G C   1 
ATOM   20660 O O   . ASP G 1 221 ? 9.975   35.545  38.211  1.00 52.71  ? 221 ASP G O   1 
ATOM   20661 C CB  . ASP G 1 221 ? 10.083  35.519  35.280  1.00 56.03  ? 221 ASP G CB  1 
ATOM   20662 C CG  . ASP G 1 221 ? 9.659   34.199  34.644  1.00 58.06  ? 221 ASP G CG  1 
ATOM   20663 O OD1 . ASP G 1 221 ? 9.368   33.225  35.383  1.00 57.34  ? 221 ASP G OD1 1 
ATOM   20664 O OD2 . ASP G 1 221 ? 9.586   34.148  33.396  1.00 64.78  ? 221 ASP G OD2 1 
ATOM   20665 N N   . GLN G 1 222 ? 11.137  33.642  37.972  1.00 51.29  ? 222 GLN G N   1 
ATOM   20666 C CA  . GLN G 1 222 ? 10.703  33.102  39.252  1.00 51.82  ? 222 GLN G CA  1 
ATOM   20667 C C   . GLN G 1 222 ? 11.801  33.176  40.310  1.00 46.48  ? 222 GLN G C   1 
ATOM   20668 O O   . GLN G 1 222 ? 11.633  32.627  41.404  1.00 42.69  ? 222 GLN G O   1 
ATOM   20669 C CB  . GLN G 1 222 ? 10.219  31.657  39.079  1.00 50.70  ? 222 GLN G CB  1 
ATOM   20670 C CG  . GLN G 1 222 ? 8.904   31.510  38.297  1.00 49.29  ? 222 GLN G CG  1 
ATOM   20671 C CD  . GLN G 1 222 ? 7.661   31.794  39.135  1.00 54.87  ? 222 GLN G CD  1 
ATOM   20672 O OE1 . GLN G 1 222 ? 7.415   31.149  40.157  1.00 56.71  ? 222 GLN G OE1 1 
ATOM   20673 N NE2 . GLN G 1 222 ? 6.871   32.769  38.700  1.00 60.69  ? 222 GLN G NE2 1 
ATOM   20674 N N   . LEU G 1 223 ? 12.908  33.865  40.009  1.00 46.26  ? 223 LEU G N   1 
ATOM   20675 C CA  . LEU G 1 223 ? 14.076  33.864  40.890  1.00 44.96  ? 223 LEU G CA  1 
ATOM   20676 C C   . LEU G 1 223 ? 13.755  34.446  42.264  1.00 43.07  ? 223 LEU G C   1 
ATOM   20677 O O   . LEU G 1 223 ? 14.178  33.893  43.291  1.00 40.13  ? 223 LEU G O   1 
ATOM   20678 C CB  . LEU G 1 223 ? 15.217  34.637  40.225  1.00 40.95  ? 223 LEU G CB  1 
ATOM   20679 C CG  . LEU G 1 223 ? 16.626  34.035  40.296  1.00 43.41  ? 223 LEU G CG  1 
ATOM   20680 C CD1 . LEU G 1 223 ? 16.593  32.538  40.109  1.00 41.31  ? 223 LEU G CD1 1 
ATOM   20681 C CD2 . LEU G 1 223 ? 17.493  34.652  39.214  1.00 48.47  ? 223 LEU G CD2 1 
ATOM   20682 N N   . ASP G 1 224 ? 13.013  35.563  42.297  1.00 39.93  ? 224 ASP G N   1 
ATOM   20683 C CA  . ASP G 1 224 ? 12.630  36.199  43.560  1.00 43.11  ? 224 ASP G CA  1 
ATOM   20684 C C   . ASP G 1 224 ? 11.922  35.213  44.478  1.00 36.90  ? 224 ASP G C   1 
ATOM   20685 O O   . ASP G 1 224 ? 12.241  35.101  45.666  1.00 32.15  ? 224 ASP G O   1 
ATOM   20686 C CB  . ASP G 1 224 ? 11.708  37.402  43.304  1.00 38.97  ? 224 ASP G CB  1 
ATOM   20687 C CG  . ASP G 1 224 ? 12.447  38.654  42.827  1.00 40.03  ? 224 ASP G CG  1 
ATOM   20688 O OD1 . ASP G 1 224 ? 13.688  38.715  42.876  1.00 39.85  ? 224 ASP G OD1 1 
ATOM   20689 O OD2 . ASP G 1 224 ? 11.756  39.615  42.421  1.00 48.29  ? 224 ASP G OD2 1 
ATOM   20690 N N   . THR G 1 225 ? 10.948  34.486  43.941  1.00 35.58  ? 225 THR G N   1 
ATOM   20691 C CA  . THR G 1 225 ? 10.150  33.634  44.810  1.00 38.07  ? 225 THR G CA  1 
ATOM   20692 C C   . THR G 1 225 ? 10.873  32.340  45.163  1.00 35.20  ? 225 THR G C   1 
ATOM   20693 O O   . THR G 1 225 ? 10.699  31.829  46.279  1.00 33.65  ? 225 THR G O   1 
ATOM   20694 C CB  . THR G 1 225 ? 8.787   33.358  44.173  1.00 39.00  ? 225 THR G CB  1 
ATOM   20695 O OG1 . THR G 1 225 ? 8.941   32.449  43.084  1.00 46.19  ? 225 THR G OG1 1 
ATOM   20696 C CG2 . THR G 1 225 ? 8.173   34.666  43.667  1.00 45.38  ? 225 THR G CG2 1 
ATOM   20697 N N   . LEU G 1 226 ? 11.692  31.815  44.247  1.00 34.67  ? 226 LEU G N   1 
ATOM   20698 C CA  . LEU G 1 226 ? 12.552  30.680  44.569  1.00 29.02  ? 226 LEU G CA  1 
ATOM   20699 C C   . LEU G 1 226 ? 13.452  31.002  45.756  1.00 32.41  ? 226 LEU G C   1 
ATOM   20700 O O   . LEU G 1 226 ? 13.547  30.221  46.710  1.00 26.69  ? 226 LEU G O   1 
ATOM   20701 C CB  . LEU G 1 226 ? 13.394  30.309  43.351  1.00 36.54  ? 226 LEU G CB  1 
ATOM   20702 C CG  . LEU G 1 226 ? 12.758  29.477  42.242  1.00 39.50  ? 226 LEU G CG  1 
ATOM   20703 C CD1 . LEU G 1 226 ? 13.707  29.400  41.043  1.00 42.45  ? 226 LEU G CD1 1 
ATOM   20704 C CD2 . LEU G 1 226 ? 12.429  28.088  42.757  1.00 35.82  ? 226 LEU G CD2 1 
ATOM   20705 N N   . ALA G 1 227 ? 14.120  32.163  45.709  1.00 32.63  ? 227 ALA G N   1 
ATOM   20706 C CA  . ALA G 1 227 ? 15.010  32.563  46.798  1.00 31.94  ? 227 ALA G CA  1 
ATOM   20707 C C   . ALA G 1 227 ? 14.236  32.749  48.096  1.00 34.81  ? 227 ALA G C   1 
ATOM   20708 O O   . ALA G 1 227 ? 14.650  32.254  49.150  1.00 30.80  ? 227 ALA G O   1 
ATOM   20709 C CB  . ALA G 1 227 ? 15.751  33.848  46.428  1.00 31.33  ? 227 ALA G CB  1 
ATOM   20710 N N   . ASP G 1 228 ? 13.106  33.474  48.032  1.00 29.46  ? 228 ASP G N   1 
ATOM   20711 C CA  . ASP G 1 228 ? 12.242  33.630  49.196  1.00 30.91  ? 228 ASP G CA  1 
ATOM   20712 C C   . ASP G 1 228 ? 11.781  32.276  49.705  1.00 34.48  ? 228 ASP G C   1 
ATOM   20713 O O   . ASP G 1 228 ? 11.700  32.051  50.918  1.00 31.98  ? 228 ASP G O   1 
ATOM   20714 C CB  . ASP G 1 228 ? 11.021  34.494  48.852  1.00 31.02  ? 228 ASP G CB  1 
ATOM   20715 C CG  . ASP G 1 228 ? 11.347  35.973  48.727  1.00 32.78  ? 228 ASP G CG  1 
ATOM   20716 O OD1 . ASP G 1 228 ? 12.524  36.328  48.524  1.00 43.70  ? 228 ASP G OD1 1 
ATOM   20717 O OD2 . ASP G 1 228 ? 10.417  36.795  48.810  1.00 40.70  ? 228 ASP G OD2 1 
ATOM   20718 N N   . THR G 1 229 ? 11.477  31.361  48.789  1.00 32.30  ? 229 THR G N   1 
ATOM   20719 C CA  . THR G 1 229 ? 10.948  30.063  49.184  1.00 31.90  ? 229 THR G CA  1 
ATOM   20720 C C   . THR G 1 229 ? 12.016  29.218  49.861  1.00 31.86  ? 229 THR G C   1 
ATOM   20721 O O   . THR G 1 229 ? 11.763  28.583  50.894  1.00 32.72  ? 229 THR G O   1 
ATOM   20722 C CB  . THR G 1 229 ? 10.389  29.349  47.955  1.00 32.38  ? 229 THR G CB  1 
ATOM   20723 O OG1 . THR G 1 229 ? 9.144   29.964  47.589  1.00 36.97  ? 229 THR G OG1 1 
ATOM   20724 C CG2 . THR G 1 229 ? 10.186  27.862  48.244  1.00 35.66  ? 229 THR G CG2 1 
ATOM   20725 N N   . LEU G 1 230 ? 13.220  29.196  49.287  1.00 30.29  ? 230 LEU G N   1 
ATOM   20726 C CA  . LEU G 1 230 ? 14.306  28.414  49.869  1.00 34.19  ? 230 LEU G CA  1 
ATOM   20727 C C   . LEU G 1 230 ? 14.739  28.993  51.207  1.00 28.71  ? 230 LEU G C   1 
ATOM   20728 O O   . LEU G 1 230 ? 14.908  28.260  52.182  1.00 34.59  ? 230 LEU G O   1 
ATOM   20729 C CB  . LEU G 1 230 ? 15.479  28.342  48.890  1.00 31.42  ? 230 LEU G CB  1 
ATOM   20730 C CG  . LEU G 1 230 ? 15.063  27.726  47.547  1.00 34.27  ? 230 LEU G CG  1 
ATOM   20731 C CD1 . LEU G 1 230 ? 16.198  27.757  46.535  1.00 44.79  ? 230 LEU G CD1 1 
ATOM   20732 C CD2 . LEU G 1 230 ? 14.560  26.325  47.742  1.00 31.73  ? 230 LEU G CD2 1 
ATOM   20733 N N   . TRP G 1 231 ? 14.897  30.311  51.283  1.00 29.90  ? 231 TRP G N   1 
ATOM   20734 C CA  . TRP G 1 231 ? 15.264  30.919  52.555  1.00 33.26  ? 231 TRP G CA  1 
ATOM   20735 C C   . TRP G 1 231 ? 14.221  30.638  53.627  1.00 33.16  ? 231 TRP G C   1 
ATOM   20736 O O   . TRP G 1 231 ? 14.562  30.441  54.799  1.00 29.35  ? 231 TRP G O   1 
ATOM   20737 C CB  . TRP G 1 231 ? 15.445  32.421  52.395  1.00 30.95  ? 231 TRP G CB  1 
ATOM   20738 C CG  . TRP G 1 231 ? 16.052  33.012  53.615  1.00 33.62  ? 231 TRP G CG  1 
ATOM   20739 C CD1 . TRP G 1 231 ? 15.422  33.751  54.566  1.00 33.19  ? 231 TRP G CD1 1 
ATOM   20740 C CD2 . TRP G 1 231 ? 17.410  32.885  54.036  1.00 31.05  ? 231 TRP G CD2 1 
ATOM   20741 N NE1 . TRP G 1 231 ? 16.305  34.107  55.550  1.00 31.52  ? 231 TRP G NE1 1 
ATOM   20742 C CE2 . TRP G 1 231 ? 17.535  33.592  55.249  1.00 27.60  ? 231 TRP G CE2 1 
ATOM   20743 C CE3 . TRP G 1 231 ? 18.536  32.240  53.505  1.00 29.57  ? 231 TRP G CE3 1 
ATOM   20744 C CZ2 . TRP G 1 231 ? 18.749  33.688  55.944  1.00 32.01  ? 231 TRP G CZ2 1 
ATOM   20745 C CZ3 . TRP G 1 231 ? 19.748  32.331  54.202  1.00 26.49  ? 231 TRP G CZ3 1 
ATOM   20746 C CH2 . TRP G 1 231 ? 19.840  33.040  55.408  1.00 32.23  ? 231 TRP G CH2 1 
ATOM   20747 N N   . SER G 1 232 ? 12.946  30.604  53.236  1.00 28.71  ? 232 SER G N   1 
ATOM   20748 C CA  . SER G 1 232 ? 11.871  30.423  54.202  1.00 34.91  ? 232 SER G CA  1 
ATOM   20749 C C   . SER G 1 232 ? 11.913  29.030  54.820  1.00 30.30  ? 232 SER G C   1 
ATOM   20750 O O   . SER G 1 232 ? 11.891  28.879  56.042  1.00 32.41  ? 232 SER G O   1 
ATOM   20751 C CB  . SER G 1 232 ? 10.512  30.671  53.526  1.00 30.29  ? 232 SER G CB  1 
ATOM   20752 O OG  . SER G 1 232 ? 9.452   30.251  54.375  1.00 30.03  ? 232 SER G OG  1 
ATOM   20753 N N   . GLN G 1 233 ? 11.983  28.003  53.991  1.00 32.07  ? 233 GLN G N   1 
ATOM   20754 C CA  . GLN G 1 233 ? 11.809  26.650  54.487  1.00 34.52  ? 233 GLN G CA  1 
ATOM   20755 C C   . GLN G 1 233 ? 13.094  26.006  54.977  1.00 36.59  ? 233 GLN G C   1 
ATOM   20756 O O   . GLN G 1 233 ? 13.026  25.013  55.707  1.00 33.68  ? 233 GLN G O   1 
ATOM   20757 C CB  . GLN G 1 233 ? 11.200  25.787  53.395  1.00 39.07  ? 233 GLN G CB  1 
ATOM   20758 C CG  . GLN G 1 233 ? 9.901   26.342  52.846  1.00 39.79  ? 233 GLN G CG  1 
ATOM   20759 C CD  . GLN G 1 233 ? 9.382   25.475  51.732  1.00 47.07  ? 233 GLN G CD  1 
ATOM   20760 O OE1 . GLN G 1 233 ? 10.068  25.273  50.725  1.00 44.92  ? 233 GLN G OE1 1 
ATOM   20761 N NE2 . GLN G 1 233 ? 8.200   24.901  51.927  1.00 44.91  ? 233 GLN G NE2 1 
ATOM   20762 N N   . LEU G 1 234 ? 14.256  26.542  54.608  1.00 36.60  ? 234 LEU G N   1 
ATOM   20763 C CA  . LEU G 1 234 ? 15.525  25.937  54.978  1.00 33.42  ? 234 LEU G CA  1 
ATOM   20764 C C   . LEU G 1 234 ? 16.220  26.670  56.115  1.00 34.96  ? 234 LEU G C   1 
ATOM   20765 O O   . LEU G 1 234 ? 17.266  26.211  56.575  1.00 33.19  ? 234 LEU G O   1 
ATOM   20766 C CB  . LEU G 1 234 ? 16.434  25.864  53.747  1.00 36.83  ? 234 LEU G CB  1 
ATOM   20767 C CG  . LEU G 1 234 ? 15.807  25.072  52.590  1.00 35.71  ? 234 LEU G CG  1 
ATOM   20768 C CD1 . LEU G 1 234 ? 16.705  25.042  51.365  1.00 34.42  ? 234 LEU G CD1 1 
ATOM   20769 C CD2 . LEU G 1 234 ? 15.451  23.640  53.025  1.00 35.58  ? 234 LEU G CD2 1 
ATOM   20770 N N   . THR G 1 235 ? 15.659  27.781  56.595  1.00 33.90  ? 235 THR G N   1 
ATOM   20771 C CA  . THR G 1 235 ? 16.204  28.495  57.739  1.00 34.43  ? 235 THR G CA  1 
ATOM   20772 C C   . THR G 1 235 ? 15.238  28.410  58.913  1.00 37.92  ? 235 THR G C   1 
ATOM   20773 O O   . THR G 1 235 ? 14.046  28.135  58.742  1.00 37.25  ? 235 THR G O   1 
ATOM   20774 C CB  . THR G 1 235 ? 16.482  29.970  57.408  1.00 34.02  ? 235 THR G CB  1 
ATOM   20775 O OG1 . THR G 1 235 ? 15.266  30.637  57.026  1.00 33.65  ? 235 THR G OG1 1 
ATOM   20776 C CG2 . THR G 1 235 ? 17.511  30.077  56.289  1.00 32.77  ? 235 THR G CG2 1 
ATOM   20777 N N   . ASP G 1 236 ? 15.774  28.635  60.112  1.00 38.69  ? 236 ASP G N   1 
ATOM   20778 C CA  . ASP G 1 236 ? 14.959  28.751  61.320  1.00 43.31  ? 236 ASP G CA  1 
ATOM   20779 C C   . ASP G 1 236 ? 15.638  29.754  62.254  1.00 44.26  ? 236 ASP G C   1 
ATOM   20780 O O   . ASP G 1 236 ? 16.520  30.512  61.837  1.00 41.97  ? 236 ASP G O   1 
ATOM   20781 C CB  . ASP G 1 236 ? 14.705  27.373  61.963  1.00 39.70  ? 236 ASP G CB  1 
ATOM   20782 C CG  . ASP G 1 236 ? 15.987  26.611  62.315  1.00 45.14  ? 236 ASP G CG  1 
ATOM   20783 O OD1 . ASP G 1 236 ? 16.913  27.203  62.902  1.00 47.68  ? 236 ASP G OD1 1 
ATOM   20784 O OD2 . ASP G 1 236 ? 16.063  25.398  62.018  1.00 48.35  ? 236 ASP G OD2 1 
ATOM   20785 N N   . THR G 1 237 ? 15.200  29.774  63.520  1.00 41.89  ? 237 THR G N   1 
ATOM   20786 C CA  . THR G 1 237 ? 15.767  30.699  64.501  1.00 43.11  ? 237 THR G CA  1 
ATOM   20787 C C   . THR G 1 237 ? 17.271  30.488  64.664  1.00 44.06  ? 237 THR G C   1 
ATOM   20788 O O   . THR G 1 237 ? 18.052  31.446  64.622  1.00 37.71  ? 237 THR G O   1 
ATOM   20789 C CB  . THR G 1 237 ? 15.076  30.540  65.859  1.00 43.66  ? 237 THR G CB  1 
ATOM   20790 O OG1 . THR G 1 237 ? 13.655  30.467  65.690  1.00 46.95  ? 237 THR G OG1 1 
ATOM   20791 C CG2 . THR G 1 237 ? 15.403  31.726  66.757  1.00 47.37  ? 237 THR G CG2 1 
ATOM   20792 N N   . GLN G 1 238 ? 17.695  29.241  64.869  1.00 42.03  ? 238 GLN G N   1 
ATOM   20793 C CA  . GLN G 1 238 ? 19.095  28.941  65.142  1.00 43.34  ? 238 GLN G CA  1 
ATOM   20794 C C   . GLN G 1 238 ? 19.928  28.771  63.884  1.00 40.82  ? 238 GLN G C   1 
ATOM   20795 O O   . GLN G 1 238 ? 21.142  28.585  63.992  1.00 44.40  ? 238 GLN G O   1 
ATOM   20796 C CB  . GLN G 1 238 ? 19.223  27.662  65.969  1.00 38.91  ? 238 GLN G CB  1 
ATOM   20797 C CG  . GLN G 1 238 ? 18.620  27.729  67.333  1.00 45.38  ? 238 GLN G CG  1 
ATOM   20798 C CD  . GLN G 1 238 ? 17.153  27.432  67.300  1.00 46.62  ? 238 GLN G CD  1 
ATOM   20799 O OE1 . GLN G 1 238 ? 16.707  26.553  66.557  1.00 54.51  ? 238 GLN G OE1 1 
ATOM   20800 N NE2 . GLN G 1 238 ? 16.380  28.162  68.105  1.00 48.44  ? 238 GLN G NE2 1 
ATOM   20801 N N   . ASN G 1 239 ? 19.315  28.826  62.703  1.00 35.90  ? 239 ASN G N   1 
ATOM   20802 C CA  . ASN G 1 239 ? 19.966  28.423  61.460  1.00 37.51  ? 239 ASN G CA  1 
ATOM   20803 C C   . ASN G 1 239 ? 19.805  29.524  60.425  1.00 38.12  ? 239 ASN G C   1 
ATOM   20804 O O   . ASN G 1 239 ? 18.880  29.493  59.611  1.00 36.67  ? 239 ASN G O   1 
ATOM   20805 C CB  . ASN G 1 239 ? 19.391  27.104  60.987  1.00 34.67  ? 239 ASN G CB  1 
ATOM   20806 C CG  . ASN G 1 239 ? 19.885  25.943  61.828  1.00 41.67  ? 239 ASN G CG  1 
ATOM   20807 O OD1 . ASN G 1 239 ? 21.061  25.603  61.777  1.00 42.72  ? 239 ASN G OD1 1 
ATOM   20808 N ND2 . ASN G 1 239 ? 19.007  25.366  62.646  1.00 39.59  ? 239 ASN G ND2 1 
ATOM   20809 N N   . GLN G 1 240 ? 20.717  30.493  60.448  1.00 34.93  ? 240 GLN G N   1 
ATOM   20810 C CA  . GLN G 1 240 ? 20.623  31.641  59.561  1.00 34.85  ? 240 GLN G CA  1 
ATOM   20811 C C   . GLN G 1 240 ? 21.608  31.547  58.395  1.00 34.24  ? 240 GLN G C   1 
ATOM   20812 O O   . GLN G 1 240 ? 21.980  32.572  57.810  1.00 30.25  ? 240 GLN G O   1 
ATOM   20813 C CB  . GLN G 1 240 ? 20.828  32.927  60.354  1.00 30.57  ? 240 GLN G CB  1 
ATOM   20814 C CG  . GLN G 1 240 ? 19.631  33.361  61.188  1.00 42.44  ? 240 GLN G CG  1 
ATOM   20815 C CD  . GLN G 1 240 ? 18.361  33.607  60.383  1.00 37.10  ? 240 GLN G CD  1 
ATOM   20816 O OE1 . GLN G 1 240 ? 18.280  34.547  59.598  1.00 36.75  ? 240 GLN G OE1 1 
ATOM   20817 N NE2 . GLN G 1 240 ? 17.352  32.787  60.612  1.00 34.96  ? 240 GLN G NE2 1 
ATOM   20818 N N   . PHE G 1 241 ? 22.035  30.335  58.054  1.00 30.71  ? 241 PHE G N   1 
ATOM   20819 C CA  . PHE G 1 241 ? 22.765  30.063  56.828  1.00 33.60  ? 241 PHE G CA  1 
ATOM   20820 C C   . PHE G 1 241 ? 22.005  29.027  56.010  1.00 26.83  ? 241 PHE G C   1 
ATOM   20821 O O   . PHE G 1 241 ? 21.290  28.185  56.546  1.00 29.35  ? 241 PHE G O   1 
ATOM   20822 C CB  . PHE G 1 241 ? 24.193  29.529  57.093  1.00 28.70  ? 241 PHE G CB  1 
ATOM   20823 C CG  . PHE G 1 241 ? 25.125  30.527  57.724  1.00 33.35  ? 241 PHE G CG  1 
ATOM   20824 C CD1 . PHE G 1 241 ? 24.965  31.884  57.504  1.00 30.85  ? 241 PHE G CD1 1 
ATOM   20825 C CD2 . PHE G 1 241 ? 26.166  30.096  58.538  1.00 32.99  ? 241 PHE G CD2 1 
ATOM   20826 C CE1 . PHE G 1 241 ? 25.810  32.799  58.082  1.00 30.38  ? 241 PHE G CE1 1 
ATOM   20827 C CE2 . PHE G 1 241 ? 27.033  31.004  59.119  1.00 36.66  ? 241 PHE G CE2 1 
ATOM   20828 C CZ  . PHE G 1 241 ? 26.852  32.366  58.892  1.00 37.07  ? 241 PHE G CZ  1 
ATOM   20829 N N   . ILE G 1 242 ? 22.199  29.076  54.707  1.00 27.31  ? 242 ILE G N   1 
ATOM   20830 C CA  . ILE G 1 242 ? 21.733  28.044  53.795  1.00 27.74  ? 242 ILE G CA  1 
ATOM   20831 C C   . ILE G 1 242 ? 22.874  27.796  52.831  1.00 31.99  ? 242 ILE G C   1 
ATOM   20832 O O   . ILE G 1 242 ? 23.616  28.714  52.470  1.00 29.49  ? 242 ILE G O   1 
ATOM   20833 C CB  . ILE G 1 242 ? 20.464  28.491  53.034  1.00 32.76  ? 242 ILE G CB  1 
ATOM   20834 C CG1 . ILE G 1 242 ? 20.092  27.552  51.909  1.00 32.83  ? 242 ILE G CG1 1 
ATOM   20835 C CG2 . ILE G 1 242 ? 20.730  29.794  52.337  1.00 39.61  ? 242 ILE G CG2 1 
ATOM   20836 C CD1 . ILE G 1 242 ? 18.893  28.082  51.110  1.00 32.81  ? 242 ILE G CD1 1 
ATOM   20837 N N   . THR G 1 243 ? 23.027  26.557  52.413  1.00 23.19  ? 243 THR G N   1 
ATOM   20838 C CA  . THR G 1 243 ? 24.029  26.242  51.423  1.00 29.22  ? 243 THR G CA  1 
ATOM   20839 C C   . THR G 1 243 ? 23.375  26.146  50.049  1.00 26.20  ? 243 THR G C   1 
ATOM   20840 O O   . THR G 1 243 ? 22.290  25.579  49.921  1.00 24.87  ? 243 THR G O   1 
ATOM   20841 C CB  . THR G 1 243 ? 24.751  24.965  51.848  1.00 30.60  ? 243 THR G CB  1 
ATOM   20842 O OG1 . THR G 1 243 ? 26.092  25.324  52.187  1.00 30.44  ? 243 THR G OG1 1 
ATOM   20843 C CG2 . THR G 1 243 ? 24.721  23.902  50.791  1.00 36.35  ? 243 THR G CG2 1 
ATOM   20844 N N   . VAL G 1 244 ? 24.005  26.754  49.032  1.00 27.14  ? 244 VAL G N   1 
ATOM   20845 C CA  . VAL G 1 244 ? 23.520  26.678  47.657  1.00 21.20  ? 244 VAL G CA  1 
ATOM   20846 C C   . VAL G 1 244 ? 24.679  26.218  46.784  1.00 24.65  ? 244 VAL G C   1 
ATOM   20847 O O   . VAL G 1 244 ? 25.765  26.801  46.836  1.00 27.59  ? 244 VAL G O   1 
ATOM   20848 C CB  . VAL G 1 244 ? 22.947  28.021  47.156  1.00 25.12  ? 244 VAL G CB  1 
ATOM   20849 C CG1 . VAL G 1 244 ? 22.327  27.851  45.759  1.00 19.87  ? 244 VAL G CG1 1 
ATOM   20850 C CG2 . VAL G 1 244 ? 21.904  28.569  48.131  1.00 26.36  ? 244 VAL G CG2 1 
ATOM   20851 N N   . GLU G 1 245 ? 24.454  25.167  45.991  1.00 25.63  ? 245 GLU G N   1 
ATOM   20852 C CA  . GLU G 1 245 ? 25.547  24.429  45.375  1.00 29.63  ? 245 GLU G CA  1 
ATOM   20853 C C   . GLU G 1 245 ? 25.185  23.963  43.981  1.00 28.38  ? 245 GLU G C   1 
ATOM   20854 O O   . GLU G 1 245 ? 24.048  23.576  43.716  1.00 26.59  ? 245 GLU G O   1 
ATOM   20855 C CB  . GLU G 1 245 ? 25.915  23.174  46.162  1.00 28.43  ? 245 GLU G CB  1 
ATOM   20856 C CG  . GLU G 1 245 ? 26.499  23.397  47.512  1.00 31.69  ? 245 GLU G CG  1 
ATOM   20857 C CD  . GLU G 1 245 ? 26.729  22.091  48.265  1.00 35.00  ? 245 GLU G CD  1 
ATOM   20858 O OE1 . GLU G 1 245 ? 26.355  20.996  47.755  1.00 33.98  ? 245 GLU G OE1 1 
ATOM   20859 O OE2 . GLU G 1 245 ? 27.299  22.169  49.368  1.00 34.67  ? 245 GLU G OE2 1 
ATOM   20860 N N   . THR G 1 246 ? 26.187  23.936  43.111  1.00 24.35  ? 246 THR G N   1 
ATOM   20861 C CA  . THR G 1 246 ? 26.028  23.242  41.848  1.00 28.85  ? 246 THR G CA  1 
ATOM   20862 C C   . THR G 1 246 ? 25.951  21.744  42.103  1.00 29.58  ? 246 THR G C   1 
ATOM   20863 O O   . THR G 1 246 ? 26.721  21.190  42.894  1.00 27.44  ? 246 THR G O   1 
ATOM   20864 C CB  . THR G 1 246 ? 27.183  23.547  40.898  1.00 30.80  ? 246 THR G CB  1 
ATOM   20865 O OG1 . THR G 1 246 ? 27.276  24.963  40.683  1.00 34.45  ? 246 THR G OG1 1 
ATOM   20866 C CG2 . THR G 1 246 ? 26.949  22.849  39.574  1.00 33.26  ? 246 THR G CG2 1 
ATOM   20867 N N   . TYR G 1 247 ? 25.016  21.092  41.418  1.00 28.30  ? 247 TYR G N   1 
ATOM   20868 C CA  . TYR G 1 247 ? 24.712  19.680  41.609  1.00 32.07  ? 247 TYR G CA  1 
ATOM   20869 C C   . TYR G 1 247 ? 25.086  18.919  40.342  1.00 33.88  ? 247 TYR G C   1 
ATOM   20870 O O   . TYR G 1 247 ? 24.501  19.150  39.280  1.00 32.98  ? 247 TYR G O   1 
ATOM   20871 C CB  . TYR G 1 247 ? 23.229  19.509  41.939  1.00 33.64  ? 247 TYR G CB  1 
ATOM   20872 C CG  . TYR G 1 247 ? 22.777  18.080  42.128  1.00 35.33  ? 247 TYR G CG  1 
ATOM   20873 C CD1 . TYR G 1 247 ? 22.333  17.321  41.047  1.00 33.49  ? 247 TYR G CD1 1 
ATOM   20874 C CD2 . TYR G 1 247 ? 22.764  17.504  43.392  1.00 31.44  ? 247 TYR G CD2 1 
ATOM   20875 C CE1 . TYR G 1 247 ? 21.908  16.026  41.218  1.00 38.32  ? 247 TYR G CE1 1 
ATOM   20876 C CE2 . TYR G 1 247 ? 22.344  16.209  43.575  1.00 39.64  ? 247 TYR G CE2 1 
ATOM   20877 C CZ  . TYR G 1 247 ? 21.922  15.471  42.483  1.00 44.76  ? 247 TYR G CZ  1 
ATOM   20878 O OH  . TYR G 1 247 ? 21.494  14.175  42.665  1.00 48.42  ? 247 TYR G OH  1 
ATOM   20879 N N   . HIS G 1 248 ? 26.050  18.016  40.455  1.00 32.34  ? 248 HIS G N   1 
ATOM   20880 C CA  . HIS G 1 248 ? 26.549  17.261  39.317  1.00 37.23  ? 248 HIS G CA  1 
ATOM   20881 C C   . HIS G 1 248 ? 25.835  15.918  39.216  1.00 41.57  ? 248 HIS G C   1 
ATOM   20882 O O   . HIS G 1 248 ? 25.324  15.392  40.210  1.00 43.29  ? 248 HIS G O   1 
ATOM   20883 C CB  . HIS G 1 248 ? 28.061  17.059  39.444  1.00 35.46  ? 248 HIS G CB  1 
ATOM   20884 C CG  . HIS G 1 248 ? 28.832  18.341  39.462  1.00 35.94  ? 248 HIS G CG  1 
ATOM   20885 N ND1 . HIS G 1 248 ? 29.401  18.880  38.330  1.00 33.85  ? 248 HIS G ND1 1 
ATOM   20886 C CD2 . HIS G 1 248 ? 29.114  19.203  40.471  1.00 35.30  ? 248 HIS G CD2 1 
ATOM   20887 C CE1 . HIS G 1 248 ? 29.998  20.017  38.638  1.00 39.01  ? 248 HIS G CE1 1 
ATOM   20888 N NE2 . HIS G 1 248 ? 29.841  20.236  39.931  1.00 30.57  ? 248 HIS G NE2 1 
ATOM   20889 N N   . ARG G 1 249 ? 25.776  15.380  37.997  1.00 41.53  ? 249 ARG G N   1 
ATOM   20890 C CA  . ARG G 1 249 ? 25.286  14.021  37.794  1.00 44.68  ? 249 ARG G CA  1 
ATOM   20891 C C   . ARG G 1 249 ? 26.376  13.045  38.215  1.00 47.28  ? 249 ARG G C   1 
ATOM   20892 O O   . ARG G 1 249 ? 27.448  13.000  37.598  1.00 48.72  ? 249 ARG G O   1 
ATOM   20893 C CB  . ARG G 1 249 ? 24.891  13.779  36.339  1.00 45.03  ? 249 ARG G CB  1 
ATOM   20894 C CG  . ARG G 1 249 ? 23.411  13.932  36.078  1.00 56.45  ? 249 ARG G CG  1 
ATOM   20895 C CD  . ARG G 1 249 ? 22.705  12.582  35.977  1.00 63.18  ? 249 ARG G CD  1 
ATOM   20896 N NE  . ARG G 1 249 ? 21.259  12.734  36.115  1.00 71.75  ? 249 ARG G NE  1 
ATOM   20897 C CZ  . ARG G 1 249 ? 20.441  11.824  36.631  1.00 75.52  ? 249 ARG G CZ  1 
ATOM   20898 N NH1 . ARG G 1 249 ? 20.893  10.661  37.080  1.00 71.26  ? 249 ARG G NH1 1 
ATOM   20899 N NH2 . ARG G 1 249 ? 19.136  12.089  36.698  1.00 69.20  ? 249 ARG G NH2 1 
ATOM   20900 N N   . ALA G 1 250 ? 26.102  12.267  39.256  1.00 40.95  ? 250 ALA G N   1 
ATOM   20901 C CA  . ALA G 1 250 ? 27.112  11.428  39.883  1.00 42.88  ? 250 ALA G CA  1 
ATOM   20902 C C   . ALA G 1 250 ? 27.115  10.046  39.244  1.00 43.98  ? 250 ALA G C   1 
ATOM   20903 O O   . ALA G 1 250 ? 26.083  9.364   39.218  1.00 40.76  ? 250 ALA G O   1 
ATOM   20904 C CB  . ALA G 1 250 ? 26.868  11.316  41.387  1.00 45.66  ? 250 ALA G CB  1 
ATOM   20905 N N   . ASP G 1 251 ? 28.286  9.634   38.751  1.00 43.24  ? 251 ASP G N   1 
ATOM   20906 C CA  . ASP G 1 251 ? 28.446  8.288   38.206  1.00 47.25  ? 251 ASP G CA  1 
ATOM   20907 C C   . ASP G 1 251 ? 28.306  7.232   39.300  1.00 47.13  ? 251 ASP G C   1 
ATOM   20908 O O   . ASP G 1 251 ? 27.649  6.204   39.107  1.00 52.11  ? 251 ASP G O   1 
ATOM   20909 C CB  . ASP G 1 251 ? 29.804  8.176   37.510  1.00 44.55  ? 251 ASP G CB  1 
ATOM   20910 C CG  . ASP G 1 251 ? 30.256  6.738   37.339  1.00 50.99  ? 251 ASP G CG  1 
ATOM   20911 O OD1 . ASP G 1 251 ? 29.409  5.876   37.004  1.00 52.60  ? 251 ASP G OD1 1 
ATOM   20912 O OD2 . ASP G 1 251 ? 31.465  6.475   37.544  1.00 54.84  ? 251 ASP G OD2 1 
ATOM   20913 N N   . GLN G 1 252 ? 28.945  7.458   40.446  1.00 48.11  ? 252 GLN G N   1 
ATOM   20914 C CA  . GLN G 1 252 ? 28.798  6.621   41.626  1.00 44.17  ? 252 GLN G CA  1 
ATOM   20915 C C   . GLN G 1 252 ? 28.789  7.521   42.848  1.00 37.77  ? 252 GLN G C   1 
ATOM   20916 O O   . GLN G 1 252 ? 29.370  8.607   42.837  1.00 38.17  ? 252 GLN G O   1 
ATOM   20917 C CB  . GLN G 1 252 ? 29.931  5.614   41.757  1.00 47.16  ? 252 GLN G CB  1 
ATOM   20918 C CG  . GLN G 1 252 ? 31.252  6.211   41.331  1.00 51.65  ? 252 GLN G CG  1 
ATOM   20919 C CD  . GLN G 1 252 ? 32.447  5.308   41.625  1.00 55.67  ? 252 GLN G CD  1 
ATOM   20920 O OE1 . GLN G 1 252 ? 32.429  4.537   42.589  1.00 58.89  ? 252 GLN G OE1 1 
ATOM   20921 N NE2 . GLN G 1 252 ? 33.505  5.447   40.847  1.00 50.42  ? 252 GLN G NE2 1 
ATOM   20922 N N   . ARG G 1 253 ? 28.136  7.056   43.902  1.00 34.50  ? 253 ARG G N   1 
ATOM   20923 C CA  . ARG G 1 253 ? 28.021  7.778   45.157  1.00 34.89  ? 253 ARG G CA  1 
ATOM   20924 C C   . ARG G 1 253 ? 28.678  6.931   46.234  1.00 34.30  ? 253 ARG G C   1 
ATOM   20925 O O   . ARG G 1 253 ? 28.774  5.711   46.087  1.00 42.70  ? 253 ARG G O   1 
ATOM   20926 C CB  . ARG G 1 253 ? 26.546  8.057   45.491  1.00 39.45  ? 253 ARG G CB  1 
ATOM   20927 C CG  . ARG G 1 253 ? 25.898  9.119   44.599  1.00 40.16  ? 253 ARG G CG  1 
ATOM   20928 C CD  . ARG G 1 253 ? 24.618  9.708   45.206  1.00 41.52  ? 253 ARG G CD  1 
ATOM   20929 N NE  . ARG G 1 253 ? 24.512  11.151  44.984  1.00 48.99  ? 253 ARG G NE  1 
ATOM   20930 C CZ  . ARG G 1 253 ? 24.226  11.736  43.822  1.00 53.26  ? 253 ARG G CZ  1 
ATOM   20931 N NH1 . ARG G 1 253 ? 23.958  11.030  42.729  1.00 48.35  ? 253 ARG G NH1 1 
ATOM   20932 N NH2 . ARG G 1 253 ? 24.208  13.068  43.753  1.00 43.58  ? 253 ARG G NH2 1 
ATOM   20933 N N   . PHE G 1 254 ? 29.163  7.564   47.303  1.00 30.79  ? 254 PHE G N   1 
ATOM   20934 C CA  . PHE G 1 254 ? 29.855  6.804   48.338  1.00 23.87  ? 254 PHE G CA  1 
ATOM   20935 C C   . PHE G 1 254 ? 29.900  7.614   49.629  1.00 22.25  ? 254 PHE G C   1 
ATOM   20936 O O   . PHE G 1 254 ? 29.734  8.829   49.624  1.00 27.57  ? 254 PHE G O   1 
ATOM   20937 C CB  . PHE G 1 254 ? 31.269  6.406   47.885  1.00 24.77  ? 254 PHE G CB  1 
ATOM   20938 C CG  . PHE G 1 254 ? 32.199  7.581   47.690  1.00 28.31  ? 254 PHE G CG  1 
ATOM   20939 C CD1 . PHE G 1 254 ? 32.912  8.105   48.755  1.00 24.61  ? 254 PHE G CD1 1 
ATOM   20940 C CD2 . PHE G 1 254 ? 32.345  8.162   46.442  1.00 25.88  ? 254 PHE G CD2 1 
ATOM   20941 C CE1 . PHE G 1 254 ? 33.740  9.207   48.586  1.00 26.97  ? 254 PHE G CE1 1 
ATOM   20942 C CE2 . PHE G 1 254 ? 33.165  9.256   46.264  1.00 28.77  ? 254 PHE G CE2 1 
ATOM   20943 C CZ  . PHE G 1 254 ? 33.871  9.778   47.348  1.00 28.81  ? 254 PHE G CZ  1 
ATOM   20944 N N   . PHE G 1 255 ? 30.099  6.921   50.739  1.00 22.93  ? 255 PHE G N   1 
ATOM   20945 C CA  . PHE G 1 255 ? 30.639  7.565   51.923  1.00 27.02  ? 255 PHE G CA  1 
ATOM   20946 C C   . PHE G 1 255 ? 31.655  6.641   52.582  1.00 24.44  ? 255 PHE G C   1 
ATOM   20947 O O   . PHE G 1 255 ? 31.601  5.416   52.439  1.00 22.80  ? 255 PHE G O   1 
ATOM   20948 C CB  . PHE G 1 255 ? 29.535  8.013   52.898  1.00 25.35  ? 255 PHE G CB  1 
ATOM   20949 C CG  . PHE G 1 255 ? 28.838  6.907   53.590  1.00 25.01  ? 255 PHE G CG  1 
ATOM   20950 C CD1 . PHE G 1 255 ? 29.249  6.479   54.849  1.00 24.56  ? 255 PHE G CD1 1 
ATOM   20951 C CD2 . PHE G 1 255 ? 27.746  6.299   52.997  1.00 25.41  ? 255 PHE G CD2 1 
ATOM   20952 C CE1 . PHE G 1 255 ? 28.574  5.459   55.494  1.00 25.19  ? 255 PHE G CE1 1 
ATOM   20953 C CE2 . PHE G 1 255 ? 27.063  5.284   53.640  1.00 25.95  ? 255 PHE G CE2 1 
ATOM   20954 C CZ  . PHE G 1 255 ? 27.478  4.862   54.890  1.00 23.82  ? 255 PHE G CZ  1 
ATOM   20955 N N   . PHE G 1 256 ? 32.636  7.257   53.232  1.00 21.58  ? 256 PHE G N   1 
ATOM   20956 C CA  . PHE G 1 256 ? 33.642  6.551   54.013  1.00 22.03  ? 256 PHE G CA  1 
ATOM   20957 C C   . PHE G 1 256 ? 33.352  6.813   55.483  1.00 22.77  ? 256 PHE G C   1 
ATOM   20958 O O   . PHE G 1 256 ? 33.077  7.956   55.857  1.00 19.97  ? 256 PHE G O   1 
ATOM   20959 C CB  . PHE G 1 256 ? 35.057  7.029   53.662  1.00 18.34  ? 256 PHE G CB  1 
ATOM   20960 C CG  . PHE G 1 256 ? 35.429  6.878   52.201  1.00 19.98  ? 256 PHE G CG  1 
ATOM   20961 C CD1 . PHE G 1 256 ? 34.803  5.938   51.387  1.00 18.37  ? 256 PHE G CD1 1 
ATOM   20962 C CD2 . PHE G 1 256 ? 36.437  7.670   51.645  1.00 21.56  ? 256 PHE G CD2 1 
ATOM   20963 C CE1 . PHE G 1 256 ? 35.152  5.791   50.052  1.00 17.44  ? 256 PHE G CE1 1 
ATOM   20964 C CE2 . PHE G 1 256 ? 36.802  7.538   50.300  1.00 22.58  ? 256 PHE G CE2 1 
ATOM   20965 C CZ  . PHE G 1 256 ? 36.160  6.586   49.499  1.00 23.27  ? 256 PHE G CZ  1 
ATOM   20966 N N   . GLU G 1 257 ? 33.376  5.763   56.305  1.00 21.74  ? 257 GLU G N   1 
ATOM   20967 C CA  . GLU G 1 257 ? 33.203  5.890   57.744  1.00 19.70  ? 257 GLU G CA  1 
ATOM   20968 C C   . GLU G 1 257 ? 34.518  5.603   58.458  1.00 21.92  ? 257 GLU G C   1 
ATOM   20969 O O   . GLU G 1 257 ? 35.238  4.657   58.109  1.00 20.92  ? 257 GLU G O   1 
ATOM   20970 C CB  . GLU G 1 257 ? 32.115  4.947   58.265  1.00 19.94  ? 257 GLU G CB  1 
ATOM   20971 C CG  . GLU G 1 257 ? 31.709  5.270   59.705  1.00 21.65  ? 257 GLU G CG  1 
ATOM   20972 C CD  . GLU G 1 257 ? 30.250  4.914   60.050  1.00 25.95  ? 257 GLU G CD  1 
ATOM   20973 O OE1 . GLU G 1 257 ? 29.638  4.016   59.405  1.00 24.08  ? 257 GLU G OE1 1 
ATOM   20974 O OE2 . GLU G 1 257 ? 29.699  5.574   60.954  1.00 23.02  ? 257 GLU G OE2 1 
ATOM   20975 N N   . TYR G 1 258 ? 34.815  6.411   59.471  1.00 22.27  ? 258 TYR G N   1 
ATOM   20976 C CA  . TYR G 1 258 ? 36.073  6.346   60.210  1.00 20.98  ? 258 TYR G CA  1 
ATOM   20977 C C   . TYR G 1 258 ? 35.781  6.345   61.698  1.00 20.47  ? 258 TYR G C   1 
ATOM   20978 O O   . TYR G 1 258 ? 34.773  6.894   62.141  1.00 21.88  ? 258 TYR G O   1 
ATOM   20979 C CB  . TYR G 1 258 ? 37.013  7.556   59.915  1.00 21.78  ? 258 TYR G CB  1 
ATOM   20980 C CG  . TYR G 1 258 ? 37.324  7.796   58.452  1.00 23.67  ? 258 TYR G CG  1 
ATOM   20981 C CD1 . TYR G 1 258 ? 36.426  8.471   57.639  1.00 19.25  ? 258 TYR G CD1 1 
ATOM   20982 C CD2 . TYR G 1 258 ? 38.517  7.351   57.892  1.00 21.11  ? 258 TYR G CD2 1 
ATOM   20983 C CE1 . TYR G 1 258 ? 36.692  8.684   56.319  1.00 23.19  ? 258 TYR G CE1 1 
ATOM   20984 C CE2 . TYR G 1 258 ? 38.792  7.556   56.541  1.00 22.47  ? 258 TYR G CE2 1 
ATOM   20985 C CZ  . TYR G 1 258 ? 37.875  8.225   55.767  1.00 23.24  ? 258 TYR G CZ  1 
ATOM   20986 O OH  . TYR G 1 258 ? 38.120  8.442   54.436  1.00 25.86  ? 258 TYR G OH  1 
ATOM   20987 N N   . HIS G 1 259 ? 36.696  5.773   62.475  1.00 21.31  ? 259 HIS G N   1 
ATOM   20988 C CA  . HIS G 1 259 ? 36.728  5.974   63.919  1.00 20.51  ? 259 HIS G CA  1 
ATOM   20989 C C   . HIS G 1 259 ? 38.003  6.720   64.318  1.00 26.96  ? 259 HIS G C   1 
ATOM   20990 O O   . HIS G 1 259 ? 39.115  6.299   63.968  1.00 24.87  ? 259 HIS G O   1 
ATOM   20991 C CB  . HIS G 1 259 ? 36.640  4.648   64.667  1.00 21.08  ? 259 HIS G CB  1 
ATOM   20992 C CG  . HIS G 1 259 ? 36.830  4.792   66.141  1.00 26.33  ? 259 HIS G CG  1 
ATOM   20993 N ND1 . HIS G 1 259 ? 38.072  4.736   66.738  1.00 28.72  ? 259 HIS G ND1 1 
ATOM   20994 C CD2 . HIS G 1 259 ? 35.942  5.021   67.137  1.00 25.82  ? 259 HIS G CD2 1 
ATOM   20995 C CE1 . HIS G 1 259 ? 37.938  4.905   68.043  1.00 29.97  ? 259 HIS G CE1 1 
ATOM   20996 N NE2 . HIS G 1 259 ? 36.657  5.088   68.311  1.00 29.86  ? 259 HIS G NE2 1 
ATOM   20997 N N   . LEU G 1 260 ? 37.834  7.817   65.064  1.00 24.28  ? 260 LEU G N   1 
ATOM   20998 C CA  . LEU G 1 260 ? 38.899  8.764   65.380  1.00 22.46  ? 260 LEU G CA  1 
ATOM   20999 C C   . LEU G 1 260 ? 39.174  8.734   66.877  1.00 26.89  ? 260 LEU G C   1 
ATOM   21000 O O   . LEU G 1 260 ? 38.236  8.847   67.680  1.00 26.30  ? 260 LEU G O   1 
ATOM   21001 C CB  . LEU G 1 260 ? 38.507  10.192  64.950  1.00 25.08  ? 260 LEU G CB  1 
ATOM   21002 C CG  . LEU G 1 260 ? 38.847  10.653  63.519  1.00 22.58  ? 260 LEU G CG  1 
ATOM   21003 C CD1 . LEU G 1 260 ? 38.237  9.698   62.503  1.00 19.70  ? 260 LEU G CD1 1 
ATOM   21004 C CD2 . LEU G 1 260 ? 38.352  12.064  63.234  1.00 20.58  ? 260 LEU G CD2 1 
ATOM   21005 N N   . ASP G 1 261 ? 40.447  8.577   67.253  1.00 26.95  ? 261 ASP G N   1 
ATOM   21006 C CA  . ASP G 1 261 ? 40.853  8.661   68.663  1.00 29.93  ? 261 ASP G CA  1 
ATOM   21007 C C   . ASP G 1 261 ? 42.141  9.485   68.753  1.00 24.61  ? 261 ASP G C   1 
ATOM   21008 O O   . ASP G 1 261 ? 42.549  10.142  67.795  1.00 27.84  ? 261 ASP G O   1 
ATOM   21009 C CB  . ASP G 1 261 ? 40.967  7.258   69.298  1.00 26.52  ? 261 ASP G CB  1 
ATOM   21010 C CG  . ASP G 1 261 ? 42.098  6.404   68.716  1.00 31.11  ? 261 ASP G CG  1 
ATOM   21011 O OD1 . ASP G 1 261 ? 42.990  6.926   68.009  1.00 36.61  ? 261 ASP G OD1 1 
ATOM   21012 O OD2 . ASP G 1 261 ? 42.093  5.178   68.962  1.00 29.70  ? 261 ASP G OD2 1 
ATOM   21013 N N   . GLY G 1 262 ? 42.795  9.448   69.914  1.00 29.46  ? 262 GLY G N   1 
ATOM   21014 C CA  . GLY G 1 262 ? 43.994  10.248  70.136  1.00 26.23  ? 262 GLY G CA  1 
ATOM   21015 C C   . GLY G 1 262 ? 45.210  9.800   69.357  1.00 26.48  ? 262 GLY G C   1 
ATOM   21016 O O   . GLY G 1 262 ? 46.228  10.499  69.368  1.00 29.94  ? 262 GLY G O   1 
ATOM   21017 N N   . ASP G 1 263 ? 45.130  8.679   68.663  1.00 28.92  ? 263 ASP G N   1 
ATOM   21018 C CA  . ASP G 1 263 ? 46.260  8.165   67.908  1.00 25.83  ? 263 ASP G CA  1 
ATOM   21019 C C   . ASP G 1 263 ? 46.063  8.204   66.402  1.00 31.17  ? 263 ASP G C   1 
ATOM   21020 O O   . ASP G 1 263 ? 47.033  8.413   65.670  1.00 32.72  ? 263 ASP G O   1 
ATOM   21021 C CB  . ASP G 1 263 ? 46.546  6.723   68.333  1.00 32.22  ? 263 ASP G CB  1 
ATOM   21022 C CG  . ASP G 1 263 ? 47.053  6.628   69.763  1.00 41.66  ? 263 ASP G CG  1 
ATOM   21023 O OD1 . ASP G 1 263 ? 47.393  7.685   70.361  1.00 38.56  ? 263 ASP G OD1 1 
ATOM   21024 O OD2 . ASP G 1 263 ? 47.114  5.493   70.286  1.00 34.71  ? 263 ASP G OD2 1 
ATOM   21025 N N   . ARG G 1 264 ? 44.846  8.002   65.902  1.00 26.52  ? 264 ARG G N   1 
ATOM   21026 C CA  . ARG G 1 264 ? 44.745  7.675   64.486  1.00 24.93  ? 264 ARG G CA  1 
ATOM   21027 C C   . ARG G 1 264 ? 43.308  7.817   64.013  1.00 26.68  ? 264 ARG G C   1 
ATOM   21028 O O   . ARG G 1 264 ? 42.366  7.762   64.803  1.00 25.52  ? 264 ARG G O   1 
ATOM   21029 C CB  . ARG G 1 264 ? 45.270  6.250   64.223  1.00 28.63  ? 264 ARG G CB  1 
ATOM   21030 C CG  . ARG G 1 264 ? 44.288  5.103   64.405  1.00 30.99  ? 264 ARG G CG  1 
ATOM   21031 C CD  . ARG G 1 264 ? 43.887  4.880   65.863  1.00 28.85  ? 264 ARG G CD  1 
ATOM   21032 N NE  . ARG G 1 264 ? 42.922  3.790   66.030  1.00 34.31  ? 264 ARG G NE  1 
ATOM   21033 C CZ  . ARG G 1 264 ? 41.598  3.933   66.019  1.00 36.03  ? 264 ARG G CZ  1 
ATOM   21034 N NH1 . ARG G 1 264 ? 41.026  5.098   65.726  1.00 25.86  ? 264 ARG G NH1 1 
ATOM   21035 N NH2 . ARG G 1 264 ? 40.828  2.883   66.309  1.00 31.45  ? 264 ARG G NH2 1 
ATOM   21036 N N   . ALA G 1 265 ? 43.149  8.041   62.728  1.00 25.99  ? 265 ALA G N   1 
ATOM   21037 C CA  . ALA G 1 265 ? 41.854  7.880   62.090  1.00 28.18  ? 265 ALA G CA  1 
ATOM   21038 C C   . ALA G 1 265 ? 41.860  6.519   61.405  1.00 22.89  ? 265 ALA G C   1 
ATOM   21039 O O   . ALA G 1 265 ? 42.692  6.264   60.532  1.00 26.15  ? 265 ALA G O   1 
ATOM   21040 C CB  . ALA G 1 265 ? 41.574  9.010   61.099  1.00 24.12  ? 265 ALA G CB  1 
ATOM   21041 N N   . ARG G 1 266 ? 40.980  5.628   61.822  1.00 23.63  ? 266 ARG G N   1 
ATOM   21042 C CA  . ARG G 1 266 ? 40.944  4.303   61.213  1.00 23.68  ? 266 ARG G CA  1 
ATOM   21043 C C   . ARG G 1 266 ? 39.771  4.235   60.247  1.00 23.81  ? 266 ARG G C   1 
ATOM   21044 O O   . ARG G 1 266 ? 38.615  4.420   60.645  1.00 23.46  ? 266 ARG G O   1 
ATOM   21045 C CB  . ARG G 1 266 ? 40.851  3.184   62.251  1.00 25.30  ? 266 ARG G CB  1 
ATOM   21046 C CG  . ARG G 1 266 ? 41.069  1.809   61.612  1.00 34.41  ? 266 ARG G CG  1 
ATOM   21047 C CD  . ARG G 1 266 ? 41.291  0.703   62.626  1.00 36.52  ? 266 ARG G CD  1 
ATOM   21048 N NE  . ARG G 1 266 ? 40.036  0.207   63.179  1.00 45.70  ? 266 ARG G NE  1 
ATOM   21049 C CZ  . ARG G 1 266 ? 39.269  -0.726  62.622  1.00 53.98  ? 266 ARG G CZ  1 
ATOM   21050 N NH1 . ARG G 1 266 ? 39.569  -1.264  61.446  1.00 57.41  ? 266 ARG G NH1 1 
ATOM   21051 N NH2 . ARG G 1 266 ? 38.169  -1.129  63.259  1.00 50.54  ? 266 ARG G NH2 1 
ATOM   21052 N N   . PHE G 1 267 ? 40.077  3.980   58.983  1.00 22.54  ? 267 PHE G N   1 
ATOM   21053 C CA  . PHE G 1 267 ? 39.059  3.712   57.988  1.00 20.92  ? 267 PHE G CA  1 
ATOM   21054 C C   . PHE G 1 267 ? 38.280  2.450   58.352  1.00 23.70  ? 267 PHE G C   1 
ATOM   21055 O O   . PHE G 1 267 ? 38.862  1.405   58.646  1.00 25.11  ? 267 PHE G O   1 
ATOM   21056 C CB  . PHE G 1 267 ? 39.733  3.557   56.633  1.00 22.06  ? 267 PHE G CB  1 
ATOM   21057 C CG  . PHE G 1 267 ? 38.787  3.263   55.519  1.00 23.00  ? 267 PHE G CG  1 
ATOM   21058 C CD1 . PHE G 1 267 ? 38.446  1.959   55.211  1.00 25.57  ? 267 PHE G CD1 1 
ATOM   21059 C CD2 . PHE G 1 267 ? 38.254  4.285   54.768  1.00 19.28  ? 267 PHE G CD2 1 
ATOM   21060 C CE1 . PHE G 1 267 ? 37.574  1.681   54.168  1.00 26.77  ? 267 PHE G CE1 1 
ATOM   21061 C CE2 . PHE G 1 267 ? 37.377  4.014   53.729  1.00 25.26  ? 267 PHE G CE2 1 
ATOM   21062 C CZ  . PHE G 1 267 ? 37.048  2.710   53.423  1.00 23.12  ? 267 PHE G CZ  1 
ATOM   21063 N N   . LEU G 1 268 ? 36.955  2.549   58.342  1.00 23.14  ? 268 LEU G N   1 
ATOM   21064 C CA  . LEU G 1 268 ? 36.099  1.422   58.687  1.00 23.27  ? 268 LEU G CA  1 
ATOM   21065 C C   . LEU G 1 268 ? 35.546  0.745   57.435  1.00 24.82  ? 268 LEU G C   1 
ATOM   21066 O O   . LEU G 1 268 ? 35.783  -0.446  57.207  1.00 22.31  ? 268 LEU G O   1 
ATOM   21067 C CB  . LEU G 1 268 ? 34.970  1.900   59.606  1.00 24.44  ? 268 LEU G CB  1 
ATOM   21068 C CG  . LEU G 1 268 ? 35.410  2.460   60.972  1.00 24.79  ? 268 LEU G CG  1 
ATOM   21069 C CD1 . LEU G 1 268 ? 34.198  2.816   61.796  1.00 17.70  ? 268 LEU G CD1 1 
ATOM   21070 C CD2 . LEU G 1 268 ? 36.317  1.487   61.762  1.00 23.42  ? 268 LEU G CD2 1 
ATOM   21071 N N   . HIS G 1 269 ? 34.847  1.499   56.592  1.00 21.83  ? 269 HIS G N   1 
ATOM   21072 C CA  . HIS G 1 269 ? 34.216  0.916   55.419  1.00 22.39  ? 269 HIS G CA  1 
ATOM   21073 C C   . HIS G 1 269 ? 33.788  2.026   54.483  1.00 21.75  ? 269 HIS G C   1 
ATOM   21074 O O   . HIS G 1 269 ? 33.636  3.183   54.886  1.00 23.67  ? 269 HIS G O   1 
ATOM   21075 C CB  . HIS G 1 269 ? 32.989  0.082   55.785  1.00 20.96  ? 269 HIS G CB  1 
ATOM   21076 C CG  . HIS G 1 269 ? 31.851  0.904   56.298  1.00 20.17  ? 269 HIS G CG  1 
ATOM   21077 N ND1 . HIS G 1 269 ? 30.849  1.380   55.481  1.00 22.52  ? 269 HIS G ND1 1 
ATOM   21078 C CD2 . HIS G 1 269 ? 31.571  1.357   57.544  1.00 19.85  ? 269 HIS G CD2 1 
ATOM   21079 C CE1 . HIS G 1 269 ? 30.002  2.093   56.204  1.00 27.37  ? 269 HIS G CE1 1 
ATOM   21080 N NE2 . HIS G 1 269 ? 30.416  2.087   57.461  1.00 22.97  ? 269 HIS G NE2 1 
ATOM   21081 N N   . SER G 1 270 ? 33.554  1.650   53.234  1.00 22.79  ? 270 SER G N   1 
ATOM   21082 C CA  . SER G 1 270 ? 32.860  2.512   52.296  1.00 22.72  ? 270 SER G CA  1 
ATOM   21083 C C   . SER G 1 270 ? 31.527  1.874   51.932  1.00 24.56  ? 270 SER G C   1 
ATOM   21084 O O   . SER G 1 270 ? 31.403  0.645   51.874  1.00 29.40  ? 270 SER G O   1 
ATOM   21085 C CB  . SER G 1 270 ? 33.701  2.781   51.034  1.00 20.89  ? 270 SER G CB  1 
ATOM   21086 O OG  . SER G 1 270 ? 33.850  1.625   50.223  1.00 30.08  ? 270 SER G OG  1 
ATOM   21087 N N   . SER G 1 271 ? 30.537  2.720   51.660  1.00 23.07  ? 271 SER G N   1 
ATOM   21088 C CA  . SER G 1 271 ? 29.196  2.247   51.382  1.00 20.67  ? 271 SER G CA  1 
ATOM   21089 C C   . SER G 1 271 ? 28.490  3.186   50.415  1.00 24.75  ? 271 SER G C   1 
ATOM   21090 O O   . SER G 1 271 ? 28.930  4.314   50.169  1.00 25.41  ? 271 SER G O   1 
ATOM   21091 C CB  . SER G 1 271 ? 28.381  2.089   52.676  1.00 25.81  ? 271 SER G CB  1 
ATOM   21092 O OG  . SER G 1 271 ? 28.970  1.115   53.526  1.00 26.37  ? 271 SER G OG  1 
ATOM   21093 N N   . ILE G 1 272 ? 27.362  2.713   49.889  1.00 25.83  ? 272 ILE G N   1 
ATOM   21094 C CA  . ILE G 1 272 ? 26.600  3.418   48.869  1.00 26.74  ? 272 ILE G CA  1 
ATOM   21095 C C   . ILE G 1 272 ? 25.173  3.552   49.354  1.00 29.14  ? 272 ILE G C   1 
ATOM   21096 O O   . ILE G 1 272 ? 24.503  2.540   49.583  1.00 30.06  ? 272 ILE G O   1 
ATOM   21097 C CB  . ILE G 1 272 ? 26.616  2.681   47.527  1.00 29.68  ? 272 ILE G CB  1 
ATOM   21098 C CG1 . ILE G 1 272 ? 28.043  2.460   47.052  1.00 28.28  ? 272 ILE G CG1 1 
ATOM   21099 C CG2 . ILE G 1 272 ? 25.828  3.472   46.501  1.00 31.54  ? 272 ILE G CG2 1 
ATOM   21100 C CD1 . ILE G 1 272 ? 28.101  1.753   45.707  1.00 33.38  ? 272 ILE G CD1 1 
ATOM   21101 N N   . LEU G 1 273 ? 24.695  4.787   49.493  1.00 32.70  ? 273 LEU G N   1 
ATOM   21102 C CA  . LEU G 1 273 ? 23.283  4.984   49.797  1.00 35.29  ? 273 LEU G CA  1 
ATOM   21103 C C   . LEU G 1 273 ? 22.474  4.793   48.529  1.00 37.64  ? 273 LEU G C   1 
ATOM   21104 O O   . LEU G 1 273 ? 22.831  5.321   47.474  1.00 39.04  ? 273 LEU G O   1 
ATOM   21105 C CB  . LEU G 1 273 ? 23.017  6.358   50.392  1.00 35.28  ? 273 LEU G CB  1 
ATOM   21106 C CG  . LEU G 1 273 ? 23.820  6.648   51.657  1.00 38.15  ? 273 LEU G CG  1 
ATOM   21107 C CD1 . LEU G 1 273 ? 23.957  8.136   51.837  1.00 36.22  ? 273 LEU G CD1 1 
ATOM   21108 C CD2 . LEU G 1 273 ? 23.146  5.995   52.853  1.00 34.21  ? 273 LEU G CD2 1 
ATOM   21109 N N   . LYS G 1 274 ? 21.401  4.020   48.626  1.00 35.78  ? 274 LYS G N   1 
ATOM   21110 C CA  . LYS G 1 274 ? 20.596  3.684   47.467  1.00 39.93  ? 274 LYS G CA  1 
ATOM   21111 C C   . LYS G 1 274 ? 19.239  4.361   47.569  1.00 41.93  ? 274 LYS G C   1 
ATOM   21112 O O   . LYS G 1 274 ? 18.720  4.580   48.666  1.00 40.91  ? 274 LYS G O   1 
ATOM   21113 C CB  . LYS G 1 274 ? 20.418  2.167   47.328  1.00 39.34  ? 274 LYS G CB  1 
ATOM   21114 C CG  . LYS G 1 274 ? 21.725  1.375   47.360  1.00 40.09  ? 274 LYS G CG  1 
ATOM   21115 C CD  . LYS G 1 274 ? 22.702  1.882   46.319  1.00 39.70  ? 274 LYS G CD  1 
ATOM   21116 C CE  . LYS G 1 274 ? 22.195  1.722   44.883  1.00 42.65  ? 274 LYS G CE  1 
ATOM   21117 N NZ  . LYS G 1 274 ? 21.504  0.422   44.660  1.00 39.00  ? 274 LYS G NZ  1 
ATOM   21118 N N   . TYR G 1 275 ? 18.687  4.698   46.404  1.00 45.70  ? 275 TYR G N   1 
ATOM   21119 C CA  . TYR G 1 275 ? 17.354  5.272   46.259  1.00 48.20  ? 275 TYR G CA  1 
ATOM   21120 C C   . TYR G 1 275 ? 16.687  4.619   45.051  1.00 52.19  ? 275 TYR G C   1 
ATOM   21121 O O   . TYR G 1 275 ? 17.231  3.695   44.437  1.00 57.12  ? 275 TYR G O   1 
ATOM   21122 C CB  . TYR G 1 275 ? 17.404  6.799   46.098  1.00 53.32  ? 275 TYR G CB  1 
ATOM   21123 C CG  . TYR G 1 275 ? 18.357  7.544   47.014  1.00 50.03  ? 275 TYR G CG  1 
ATOM   21124 C CD1 . TYR G 1 275 ? 19.741  7.463   46.861  1.00 47.67  ? 275 TYR G CD1 1 
ATOM   21125 C CD2 . TYR G 1 275 ? 17.861  8.345   48.035  1.00 53.35  ? 275 TYR G CD2 1 
ATOM   21126 C CE1 . TYR G 1 275 ? 20.599  8.163   47.712  1.00 48.29  ? 275 TYR G CE1 1 
ATOM   21127 C CE2 . TYR G 1 275 ? 18.705  9.042   48.884  1.00 50.29  ? 275 TYR G CE2 1 
ATOM   21128 C CZ  . TYR G 1 275 ? 20.067  8.950   48.724  1.00 46.93  ? 275 TYR G CZ  1 
ATOM   21129 O OH  . TYR G 1 275 ? 20.885  9.649   49.585  1.00 46.90  ? 275 TYR G OH  1 
ATOM   21130 N N   . GLU G 1 276 ? 15.492  5.096   44.705  1.00 57.93  ? 276 GLU G N   1 
ATOM   21131 C CA  . GLU G 1 276 ? 14.863  4.694   43.450  1.00 57.70  ? 276 GLU G CA  1 
ATOM   21132 C C   . GLU G 1 276 ? 14.525  5.922   42.614  1.00 59.14  ? 276 GLU G C   1 
ATOM   21133 O O   . GLU G 1 276 ? 15.112  6.992   42.818  1.00 52.01  ? 276 GLU G O   1 
ATOM   21134 C CB  . GLU G 1 276 ? 13.613  3.862   43.711  1.00 54.46  ? 276 GLU G CB  1 
ATOM   21135 C CG  . GLU G 1 276 ? 13.602  2.543   42.960  1.00 56.77  ? 276 GLU G CG  1 
ATOM   21136 C CD  . GLU G 1 276 ? 12.771  1.482   43.651  1.00 52.72  ? 276 GLU G CD  1 
ATOM   21137 O OE1 . GLU G 1 276 ? 11.531  1.627   43.654  1.00 63.86  ? 276 GLU G OE1 1 
ATOM   21138 O OE2 . GLU G 1 276 ? 13.344  0.507   44.182  1.00 52.63  ? 276 GLU G OE2 1 
ATOM   21139 N N   . GLN G 1 277 ? 13.596  5.779   41.666  1.00 68.68  ? 277 GLN G N   1 
ATOM   21140 C CA  . GLN G 1 277 ? 13.095  6.926   40.893  1.00 71.93  ? 277 GLN G CA  1 
ATOM   21141 C C   . GLN G 1 277 ? 11.643  7.253   41.237  1.00 66.88  ? 277 GLN G C   1 
ATOM   21142 O O   . GLN G 1 277 ? 11.223  8.413   41.188  1.00 60.02  ? 277 GLN G O   1 
ATOM   21143 C CB  . GLN G 1 277 ? 13.219  6.678   39.385  1.00 75.94  ? 277 GLN G CB  1 
ATOM   21144 C CG  . GLN G 1 277 ? 12.535  7.754   38.515  1.00 78.58  ? 277 GLN G CG  1 
ATOM   21145 C CD  . GLN G 1 277 ? 13.485  8.849   38.033  1.00 80.91  ? 277 GLN G CD  1 
ATOM   21146 O OE1 . GLN G 1 277 ? 13.566  9.930   38.627  1.00 73.28  ? 277 GLN G OE1 1 
ATOM   21147 N NE2 . GLN G 1 277 ? 14.197  8.575   36.941  1.00 80.57  ? 277 GLN G NE2 1 
ATOM   21148 N N   . SER G 1 285 ? 11.433  13.157  45.879  1.00 66.19  ? 285 SER G N   1 
ATOM   21149 C CA  . SER G 1 285 ? 12.410  13.061  44.799  1.00 65.19  ? 285 SER G CA  1 
ATOM   21150 C C   . SER G 1 285 ? 13.168  11.741  44.882  1.00 67.20  ? 285 SER G C   1 
ATOM   21151 O O   . SER G 1 285 ? 13.749  11.286  43.894  1.00 61.97  ? 285 SER G O   1 
ATOM   21152 C CB  . SER G 1 285 ? 13.393  14.226  44.861  1.00 56.92  ? 285 SER G CB  1 
ATOM   21153 O OG  . SER G 1 285 ? 12.866  15.301  45.629  1.00 56.12  ? 285 SER G OG  1 
ATOM   21154 N N   . ALA G 1 286 ? 13.156  11.136  46.071  1.00 69.88  ? 286 ALA G N   1 
ATOM   21155 C CA  . ALA G 1 286 ? 13.934  9.925   46.337  1.00 65.33  ? 286 ALA G CA  1 
ATOM   21156 C C   . ALA G 1 286 ? 13.152  8.925   47.177  1.00 60.63  ? 286 ALA G C   1 
ATOM   21157 O O   . ALA G 1 286 ? 13.658  8.418   48.180  1.00 60.47  ? 286 ALA G O   1 
ATOM   21158 C CB  . ALA G 1 286 ? 15.240  10.282  47.029  1.00 57.63  ? 286 ALA G CB  1 
ATOM   21159 N N   . TRP G 1 288 ? 15.183  7.243   50.327  1.00 50.03  ? 288 TRP G N   1 
ATOM   21160 C CA  . TRP G 1 288 ? 16.246  6.384   50.825  1.00 46.68  ? 288 TRP G CA  1 
ATOM   21161 C C   . TRP G 1 288 ? 15.690  4.991   51.135  1.00 43.34  ? 288 TRP G C   1 
ATOM   21162 O O   . TRP G 1 288 ? 14.818  4.840   51.990  1.00 44.85  ? 288 TRP G O   1 
ATOM   21163 C CB  . TRP G 1 288 ? 16.901  6.992   52.065  1.00 44.34  ? 288 TRP G CB  1 
ATOM   21164 C CG  . TRP G 1 288 ? 17.999  6.127   52.640  1.00 42.96  ? 288 TRP G CG  1 
ATOM   21165 C CD1 . TRP G 1 288 ? 18.995  5.492   51.952  1.00 40.62  ? 288 TRP G CD1 1 
ATOM   21166 C CD2 . TRP G 1 288 ? 18.196  5.798   54.019  1.00 45.19  ? 288 TRP G CD2 1 
ATOM   21167 N NE1 . TRP G 1 288 ? 19.799  4.787   52.818  1.00 37.82  ? 288 TRP G NE1 1 
ATOM   21168 C CE2 . TRP G 1 288 ? 19.333  4.963   54.094  1.00 38.11  ? 288 TRP G CE2 1 
ATOM   21169 C CE3 . TRP G 1 288 ? 17.521  6.129   55.200  1.00 42.66  ? 288 TRP G CE3 1 
ATOM   21170 C CZ2 . TRP G 1 288 ? 19.812  4.459   55.300  1.00 37.89  ? 288 TRP G CZ2 1 
ATOM   21171 C CZ3 . TRP G 1 288 ? 18.005  5.622   56.403  1.00 46.17  ? 288 TRP G CZ3 1 
ATOM   21172 C CH2 . TRP G 1 288 ? 19.138  4.796   56.438  1.00 39.34  ? 288 TRP G CH2 1 
ATOM   21173 N N   . ILE G 1 289 ? 16.203  3.980   50.438  1.00 33.31  ? 289 ILE G N   1 
ATOM   21174 C CA  . ILE G 1 289 ? 15.654  2.636   50.528  1.00 35.18  ? 289 ILE G CA  1 
ATOM   21175 C C   . ILE G 1 289 ? 16.646  1.615   51.065  1.00 34.85  ? 289 ILE G C   1 
ATOM   21176 O O   . ILE G 1 289 ? 16.220  0.522   51.473  1.00 36.75  ? 289 ILE G O   1 
ATOM   21177 C CB  . ILE G 1 289 ? 15.106  2.176   49.161  1.00 38.95  ? 289 ILE G CB  1 
ATOM   21178 C CG1 . ILE G 1 289 ? 16.191  2.274   48.085  1.00 36.36  ? 289 ILE G CG1 1 
ATOM   21179 C CG2 . ILE G 1 289 ? 13.907  3.032   48.761  1.00 33.24  ? 289 ILE G CG2 1 
ATOM   21180 C CD1 . ILE G 1 289 ? 15.732  1.830   46.715  1.00 45.03  ? 289 ILE G CD1 1 
ATOM   21181 N N   . GLY G 1 290 ? 17.942  1.909   51.083  1.00 35.44  ? 290 GLY G N   1 
ATOM   21182 C CA  . GLY G 1 290 ? 18.901  0.987   51.660  1.00 40.11  ? 290 GLY G CA  1 
ATOM   21183 C C   . GLY G 1 290 ? 20.327  1.406   51.347  1.00 35.15  ? 290 GLY G C   1 
ATOM   21184 O O   . GLY G 1 290 ? 20.581  2.526   50.907  1.00 37.07  ? 290 GLY G O   1 
ATOM   21185 N N   . LEU G 1 291 ? 21.257  0.487   51.613  1.00 36.91  ? 291 LEU G N   1 
ATOM   21186 C CA  . LEU G 1 291 ? 22.630  0.628   51.148  1.00 34.23  ? 291 LEU G CA  1 
ATOM   21187 C C   . LEU G 1 291 ? 23.169  -0.756  50.808  1.00 35.57  ? 291 LEU G C   1 
ATOM   21188 O O   . LEU G 1 291 ? 22.734  -1.758  51.378  1.00 31.88  ? 291 LEU G O   1 
ATOM   21189 C CB  . LEU G 1 291 ? 23.489  1.386   52.169  1.00 34.22  ? 291 LEU G CB  1 
ATOM   21190 C CG  . LEU G 1 291 ? 23.885  0.881   53.543  1.00 32.25  ? 291 LEU G CG  1 
ATOM   21191 C CD1 . LEU G 1 291 ? 25.053  -0.056  53.418  1.00 37.52  ? 291 LEU G CD1 1 
ATOM   21192 C CD2 . LEU G 1 291 ? 24.254  2.071   54.429  1.00 35.95  ? 291 LEU G CD2 1 
ATOM   21193 N N   . ASP G 1 292 ? 24.099  -0.808  49.856  1.00 32.71  ? 292 ASP G N   1 
ATOM   21194 C CA  . ASP G 1 292 ? 24.303  -1.997  49.018  1.00 41.57  ? 292 ASP G CA  1 
ATOM   21195 C C   . ASP G 1 292 ? 25.771  -2.305  48.875  1.00 45.69  ? 292 ASP G C   1 
ATOM   21196 O O   . ASP G 1 292 ? 26.280  -2.474  47.762  1.00 51.28  ? 292 ASP G O   1 
ATOM   21197 C CB  . ASP G 1 292 ? 23.736  -1.791  47.613  1.00 37.91  ? 292 ASP G CB  1 
ATOM   21198 C CG  . ASP G 1 292 ? 22.337  -2.293  47.482  1.00 48.54  ? 292 ASP G CG  1 
ATOM   21199 O OD1 . ASP G 1 292 ? 21.612  -2.300  48.511  1.00 48.49  ? 292 ASP G OD1 1 
ATOM   21200 O OD2 . ASP G 1 292 ? 21.951  -2.667  46.348  1.00 61.55  ? 292 ASP G OD2 1 
ATOM   21201 N N   . SER G 1 293 ? 26.504  -2.343  49.985  1.00 34.74  ? 293 SER G N   1 
ATOM   21202 C CA  . SER G 1 293 ? 27.795  -1.676  49.976  1.00 30.05  ? 293 SER G CA  1 
ATOM   21203 C C   . SER G 1 293 ? 29.004  -2.210  50.732  1.00 36.16  ? 293 SER G C   1 
ATOM   21204 O O   . SER G 1 293 ? 29.181  -1.951  51.940  1.00 31.80  ? 293 SER G O   1 
ATOM   21205 C CB  . SER G 1 293 ? 27.500  -0.253  50.407  1.00 32.29  ? 293 SER G CB  1 
ATOM   21206 O OG  . SER G 1 293 ? 26.153  0.096   50.146  1.00 36.86  ? 293 SER G OG  1 
ATOM   21207 N N   . PRO G 1 294 ? 29.875  -2.942  50.034  1.00 32.13  ? 294 PRO G N   1 
ATOM   21208 C CA  . PRO G 1 294 ? 31.242  -2.434  49.824  1.00 31.39  ? 294 PRO G CA  1 
ATOM   21209 C C   . PRO G 1 294 ? 31.148  -1.483  48.638  1.00 30.50  ? 294 PRO G C   1 
ATOM   21210 O O   . PRO G 1 294 ? 30.639  -1.864  47.586  1.00 31.79  ? 294 PRO G O   1 
ATOM   21211 C CB  . PRO G 1 294 ? 32.057  -3.690  49.485  1.00 36.16  ? 294 PRO G CB  1 
ATOM   21212 C CG  . PRO G 1 294 ? 31.090  -4.850  49.488  1.00 36.49  ? 294 PRO G CG  1 
ATOM   21213 C CD  . PRO G 1 294 ? 29.679  -4.306  49.539  1.00 31.24  ? 294 PRO G CD  1 
ATOM   21214 N N   . SER G 1 295 ? 31.554  -0.230  48.817  1.00 34.39  ? 295 SER G N   1 
ATOM   21215 C CA  . SER G 1 295 ? 31.390  0.710   47.708  1.00 33.33  ? 295 SER G CA  1 
ATOM   21216 C C   . SER G 1 295 ? 32.295  0.321   46.536  1.00 31.73  ? 295 SER G C   1 
ATOM   21217 O O   . SER G 1 295 ? 33.166  -0.546  46.641  1.00 36.25  ? 295 SER G O   1 
ATOM   21218 C CB  . SER G 1 295 ? 31.683  2.147   48.160  1.00 32.54  ? 295 SER G CB  1 
ATOM   21219 O OG  . SER G 1 295 ? 32.890  2.655   47.583  1.00 30.02  ? 295 SER G OG  1 
ATOM   21220 N N   . ARG G 1 296 ? 32.085  0.981   45.405  1.00 31.50  ? 296 ARG G N   1 
ATOM   21221 C CA  . ARG G 1 296 ? 32.934  0.796   44.237  1.00 34.31  ? 296 ARG G CA  1 
ATOM   21222 C C   . ARG G 1 296 ? 33.973  1.909   44.069  1.00 35.53  ? 296 ARG G C   1 
ATOM   21223 O O   . ARG G 1 296 ? 34.615  1.988   43.018  1.00 37.15  ? 296 ARG G O   1 
ATOM   21224 C CB  . ARG G 1 296 ? 32.070  0.687   42.973  1.00 38.74  ? 296 ARG G CB  1 
ATOM   21225 C CG  . ARG G 1 296 ? 31.652  -0.752  42.604  1.00 46.52  ? 296 ARG G CG  1 
ATOM   21226 C CD  . ARG G 1 296 ? 30.302  -1.177  43.207  1.00 46.99  ? 296 ARG G CD  1 
ATOM   21227 N NE  . ARG G 1 296 ? 29.150  -0.606  42.515  1.00 56.12  ? 296 ARG G NE  1 
ATOM   21228 C CZ  . ARG G 1 296 ? 27.891  -0.702  42.932  1.00 55.89  ? 296 ARG G CZ  1 
ATOM   21229 N NH1 . ARG G 1 296 ? 27.575  -1.345  44.049  1.00 49.97  ? 296 ARG G NH1 1 
ATOM   21230 N NH2 . ARG G 1 296 ? 26.926  -0.130  42.216  1.00 48.77  ? 296 ARG G NH2 1 
ATOM   21231 N N   . SER G 1 297 ? 34.166  2.761   45.080  1.00 31.84  ? 297 SER G N   1 
ATOM   21232 C CA  . SER G 1 297 ? 34.929  3.993   44.920  1.00 31.94  ? 297 SER G CA  1 
ATOM   21233 C C   . SER G 1 297 ? 36.177  4.053   45.792  1.00 30.44  ? 297 SER G C   1 
ATOM   21234 O O   . SER G 1 297 ? 36.689  5.148   46.036  1.00 32.37  ? 297 SER G O   1 
ATOM   21235 C CB  . SER G 1 297 ? 34.062  5.203   45.238  1.00 29.03  ? 297 SER G CB  1 
ATOM   21236 O OG  . SER G 1 297 ? 32.850  5.142   44.532  1.00 37.35  ? 297 SER G OG  1 
ATOM   21237 N N   . GLU G 1 298 ? 36.665  2.920   46.283  1.00 30.83  ? 298 GLU G N   1 
ATOM   21238 C CA  . GLU G 1 298 ? 37.865  2.882   47.120  1.00 29.69  ? 298 GLU G CA  1 
ATOM   21239 C C   . GLU G 1 298 ? 39.083  2.893   46.202  1.00 36.35  ? 298 GLU G C   1 
ATOM   21240 O O   . GLU G 1 298 ? 39.485  1.857   45.676  1.00 33.60  ? 298 GLU G O   1 
ATOM   21241 C CB  . GLU G 1 298 ? 37.863  1.656   48.026  1.00 33.09  ? 298 GLU G CB  1 
ATOM   21242 C CG  . GLU G 1 298 ? 36.938  1.768   49.246  1.00 28.95  ? 298 GLU G CG  1 
ATOM   21243 C CD  . GLU G 1 298 ? 36.849  0.481   50.065  1.00 28.02  ? 298 GLU G CD  1 
ATOM   21244 O OE1 . GLU G 1 298 ? 37.892  -0.189  50.277  1.00 43.48  ? 298 GLU G OE1 1 
ATOM   21245 O OE2 . GLU G 1 298 ? 35.732  0.140   50.513  1.00 27.48  ? 298 GLU G OE2 1 
ATOM   21246 N N   . PHE G 1 299 ? 39.659  4.072   45.990  1.00 36.98  ? 299 PHE G N   1 
ATOM   21247 C CA  . PHE G 1 299 ? 40.926  4.192   45.279  1.00 38.24  ? 299 PHE G CA  1 
ATOM   21248 C C   . PHE G 1 299 ? 41.565  5.519   45.672  1.00 31.40  ? 299 PHE G C   1 
ATOM   21249 O O   . PHE G 1 299 ? 40.958  6.341   46.361  1.00 33.29  ? 299 PHE G O   1 
ATOM   21250 C CB  . PHE G 1 299 ? 40.735  4.098   43.768  1.00 36.87  ? 299 PHE G CB  1 
ATOM   21251 C CG  . PHE G 1 299 ? 39.630  4.973   43.243  1.00 35.19  ? 299 PHE G CG  1 
ATOM   21252 C CD1 . PHE G 1 299 ? 39.791  6.342   43.221  1.00 34.74  ? 299 PHE G CD1 1 
ATOM   21253 C CD2 . PHE G 1 299 ? 38.448  4.419   42.740  1.00 39.27  ? 299 PHE G CD2 1 
ATOM   21254 C CE1 . PHE G 1 299 ? 38.802  7.152   42.739  1.00 34.27  ? 299 PHE G CE1 1 
ATOM   21255 C CE2 . PHE G 1 299 ? 37.420  5.233   42.240  1.00 36.46  ? 299 PHE G CE2 1 
ATOM   21256 C CZ  . PHE G 1 299 ? 37.601  6.599   42.242  1.00 33.00  ? 299 PHE G CZ  1 
ATOM   21257 N N   . GLU G 1 300 ? 42.778  5.743   45.175  1.00 36.21  ? 300 GLU G N   1 
ATOM   21258 C CA  . GLU G 1 300 ? 43.599  6.840   45.678  1.00 37.17  ? 300 GLU G CA  1 
ATOM   21259 C C   . GLU G 1 300 ? 42.895  8.186   45.549  1.00 30.99  ? 300 GLU G C   1 
ATOM   21260 O O   . GLU G 1 300 ? 42.925  8.997   46.484  1.00 28.85  ? 300 GLU G O   1 
ATOM   21261 C CB  . GLU G 1 300 ? 44.944  6.848   44.951  1.00 38.92  ? 300 GLU G CB  1 
ATOM   21262 C CG  . GLU G 1 300 ? 46.082  6.163   45.715  1.00 50.78  ? 300 GLU G CG  1 
ATOM   21263 C CD  . GLU G 1 300 ? 45.909  4.643   45.861  1.00 59.11  ? 300 GLU G CD  1 
ATOM   21264 O OE1 . GLU G 1 300 ? 44.815  4.109   45.546  1.00 55.29  ? 300 GLU G OE1 1 
ATOM   21265 O OE2 . GLU G 1 300 ? 46.881  3.975   46.293  1.00 58.11  ? 300 GLU G OE2 1 
ATOM   21266 N N   . ALA G 1 301 ? 42.246  8.443   44.409  1.00 29.39  ? 301 ALA G N   1 
ATOM   21267 C CA  . ALA G 1 301 ? 41.695  9.776   44.175  1.00 33.15  ? 301 ALA G CA  1 
ATOM   21268 C C   . ALA G 1 301 ? 40.543  10.109  45.120  1.00 23.44  ? 301 ALA G C   1 
ATOM   21269 O O   . ALA G 1 301 ? 40.195  11.274  45.260  1.00 27.48  ? 301 ALA G O   1 
ATOM   21270 C CB  . ALA G 1 301 ? 41.245  9.916   42.718  1.00 28.85  ? 301 ALA G CB  1 
ATOM   21271 N N   . THR G 1 302 ? 39.941  9.120   45.762  1.00 26.78  ? 302 THR G N   1 
ATOM   21272 C CA  . THR G 1 302 ? 38.959  9.390   46.810  1.00 30.88  ? 302 THR G CA  1 
ATOM   21273 C C   . THR G 1 302 ? 39.541  9.231   48.211  1.00 26.76  ? 302 THR G C   1 
ATOM   21274 O O   . THR G 1 302 ? 39.403  10.135  49.035  1.00 26.03  ? 302 THR G O   1 
ATOM   21275 C CB  . THR G 1 302 ? 37.725  8.482   46.660  1.00 27.45  ? 302 THR G CB  1 
ATOM   21276 O OG1 . THR G 1 302 ? 38.130  7.109   46.627  1.00 24.28  ? 302 THR G OG1 1 
ATOM   21277 C CG2 . THR G 1 302 ? 36.939  8.836   45.396  1.00 23.37  ? 302 THR G CG2 1 
ATOM   21278 N N   . LEU G 1 303 ? 40.186  8.096   48.496  1.00 25.29  ? 303 LEU G N   1 
ATOM   21279 C CA  . LEU G 1 303 ? 40.636  7.828   49.861  1.00 28.29  ? 303 LEU G CA  1 
ATOM   21280 C C   . LEU G 1 303 ? 41.639  8.869   50.332  1.00 27.85  ? 303 LEU G C   1 
ATOM   21281 O O   . LEU G 1 303 ? 41.669  9.209   51.518  1.00 24.09  ? 303 LEU G O   1 
ATOM   21282 C CB  . LEU G 1 303 ? 41.271  6.438   49.959  1.00 27.42  ? 303 LEU G CB  1 
ATOM   21283 C CG  . LEU G 1 303 ? 40.410  5.212   49.704  1.00 28.18  ? 303 LEU G CG  1 
ATOM   21284 C CD1 . LEU G 1 303 ? 41.304  4.008   49.477  1.00 24.41  ? 303 LEU G CD1 1 
ATOM   21285 C CD2 . LEU G 1 303 ? 39.485  4.990   50.881  1.00 26.35  ? 303 LEU G CD2 1 
ATOM   21286 N N   . LYS G 1 304 ? 42.473  9.391   49.418  1.00 28.49  ? 304 LYS G N   1 
ATOM   21287 C CA  . LYS G 1 304 ? 43.546  10.283  49.844  1.00 27.61  ? 304 LYS G CA  1 
ATOM   21288 C C   . LYS G 1 304 ? 43.024  11.655  50.275  1.00 24.27  ? 304 LYS G C   1 
ATOM   21289 O O   . LYS G 1 304 ? 43.284  12.059  51.421  1.00 24.27  ? 304 LYS G O   1 
ATOM   21290 C CB  . LYS G 1 304 ? 44.619  10.368  48.754  1.00 31.01  ? 304 LYS G CB  1 
ATOM   21291 C CG  . LYS G 1 304 ? 45.767  11.324  49.072  1.00 34.43  ? 304 LYS G CG  1 
ATOM   21292 C CD  . LYS G 1 304 ? 45.939  12.387  47.978  1.00 38.82  ? 304 LYS G CD  1 
ATOM   21293 C CE  . LYS G 1 304 ? 44.890  13.487  48.080  1.00 38.90  ? 304 LYS G CE  1 
ATOM   21294 N NZ  . LYS G 1 304 ? 45.065  14.332  49.304  1.00 36.61  ? 304 LYS G NZ  1 
ATOM   21295 N N   . PRO G 1 305 ? 42.291  12.410  49.439  1.00 25.00  ? 305 PRO G N   1 
ATOM   21296 C CA  . PRO G 1 305 ? 41.751  13.687  49.941  1.00 21.23  ? 305 PRO G CA  1 
ATOM   21297 C C   . PRO G 1 305 ? 40.846  13.488  51.141  1.00 26.48  ? 305 PRO G C   1 
ATOM   21298 O O   . PRO G 1 305 ? 40.884  14.280  52.088  1.00 23.72  ? 305 PRO G O   1 
ATOM   21299 C CB  . PRO G 1 305 ? 40.968  14.247  48.749  1.00 19.94  ? 305 PRO G CB  1 
ATOM   21300 C CG  . PRO G 1 305 ? 41.226  13.351  47.616  1.00 23.80  ? 305 PRO G CG  1 
ATOM   21301 C CD  . PRO G 1 305 ? 41.700  12.056  48.138  1.00 27.09  ? 305 PRO G CD  1 
ATOM   21302 N N   . ALA G 1 306 ? 40.041  12.420  51.140  1.00 25.18  ? 306 ALA G N   1 
ATOM   21303 C CA  . ALA G 1 306 ? 39.182  12.158  52.292  1.00 26.57  ? 306 ALA G CA  1 
ATOM   21304 C C   . ALA G 1 306 ? 40.013  11.935  53.554  1.00 22.30  ? 306 ALA G C   1 
ATOM   21305 O O   . ALA G 1 306 ? 39.714  12.506  54.612  1.00 22.73  ? 306 ALA G O   1 
ATOM   21306 C CB  . ALA G 1 306 ? 38.274  10.964  52.001  1.00 22.15  ? 306 ALA G CB  1 
ATOM   21307 N N   . GLU G 1 307 ? 41.075  11.130  53.447  1.00 20.44  ? 307 GLU G N   1 
ATOM   21308 C CA  . GLU G 1 307 ? 41.968  10.897  54.581  1.00 27.09  ? 307 GLU G CA  1 
ATOM   21309 C C   . GLU G 1 307 ? 42.583  12.199  55.071  1.00 25.87  ? 307 GLU G C   1 
ATOM   21310 O O   . GLU G 1 307 ? 42.652  12.453  56.281  1.00 24.61  ? 307 GLU G O   1 
ATOM   21311 C CB  . GLU G 1 307 ? 43.075  9.912   54.200  1.00 26.25  ? 307 GLU G CB  1 
ATOM   21312 C CG  . GLU G 1 307 ? 44.147  9.763   55.275  1.00 30.44  ? 307 GLU G CG  1 
ATOM   21313 C CD  . GLU G 1 307 ? 45.403  9.018   54.789  1.00 40.65  ? 307 GLU G CD  1 
ATOM   21314 O OE1 . GLU G 1 307 ? 45.473  8.614   53.605  1.00 38.91  ? 307 GLU G OE1 1 
ATOM   21315 O OE2 . GLU G 1 307 ? 46.325  8.830   55.607  1.00 41.71  ? 307 GLU G OE2 1 
ATOM   21316 N N   . GLU G 1 308 ? 43.071  13.019  54.144  1.00 22.30  ? 308 GLU G N   1 
ATOM   21317 C CA  . GLU G 1 308 ? 43.577  14.336  54.507  1.00 21.86  ? 308 GLU G CA  1 
ATOM   21318 C C   . GLU G 1 308 ? 42.566  15.098  55.338  1.00 23.63  ? 308 GLU G C   1 
ATOM   21319 O O   . GLU G 1 308 ? 42.871  15.583  56.437  1.00 21.92  ? 308 GLU G O   1 
ATOM   21320 C CB  . GLU G 1 308 ? 43.894  15.119  53.244  1.00 28.20  ? 308 GLU G CB  1 
ATOM   21321 C CG  . GLU G 1 308 ? 45.306  15.581  53.083  1.00 38.09  ? 308 GLU G CG  1 
ATOM   21322 C CD  . GLU G 1 308 ? 45.406  16.502  51.872  1.00 49.85  ? 308 GLU G CD  1 
ATOM   21323 O OE1 . GLU G 1 308 ? 44.975  17.682  51.973  1.00 45.95  ? 308 GLU G OE1 1 
ATOM   21324 O OE2 . GLU G 1 308 ? 45.896  16.037  50.816  1.00 46.84  ? 308 GLU G OE2 1 
ATOM   21325 N N   . PHE G 1 309 ? 41.342  15.216  54.819  1.00 20.51  ? 309 PHE G N   1 
ATOM   21326 C CA  . PHE G 1 309 ? 40.326  16.007  55.502  1.00 21.90  ? 309 PHE G CA  1 
ATOM   21327 C C   . PHE G 1 309 ? 39.970  15.398  56.852  1.00 25.14  ? 309 PHE G C   1 
ATOM   21328 O O   . PHE G 1 309 ? 39.841  16.111  57.856  1.00 21.88  ? 309 PHE G O   1 
ATOM   21329 C CB  . PHE G 1 309 ? 39.074  16.119  54.638  1.00 21.42  ? 309 PHE G CB  1 
ATOM   21330 C CG  . PHE G 1 309 ? 38.043  17.016  55.217  1.00 19.98  ? 309 PHE G CG  1 
ATOM   21331 C CD1 . PHE G 1 309 ? 37.122  16.549  56.131  1.00 21.74  ? 309 PHE G CD1 1 
ATOM   21332 C CD2 . PHE G 1 309 ? 38.029  18.347  54.897  1.00 19.52  ? 309 PHE G CD2 1 
ATOM   21333 C CE1 . PHE G 1 309 ? 36.178  17.405  56.670  1.00 20.05  ? 309 PHE G CE1 1 
ATOM   21334 C CE2 . PHE G 1 309 ? 37.086  19.196  55.441  1.00 21.96  ? 309 PHE G CE2 1 
ATOM   21335 C CZ  . PHE G 1 309 ? 36.168  18.720  56.325  1.00 17.15  ? 309 PHE G CZ  1 
ATOM   21336 N N   . ILE G 1 310 ? 39.767  14.082  56.889  1.00 20.45  ? 310 ILE G N   1 
ATOM   21337 C CA  . ILE G 1 310 ? 39.315  13.493  58.143  1.00 22.87  ? 310 ILE G CA  1 
ATOM   21338 C C   . ILE G 1 310 ? 40.397  13.643  59.193  1.00 27.22  ? 310 ILE G C   1 
ATOM   21339 O O   . ILE G 1 310 ? 40.106  13.850  60.378  1.00 25.42  ? 310 ILE G O   1 
ATOM   21340 C CB  . ILE G 1 310 ? 38.907  12.022  57.939  1.00 24.57  ? 310 ILE G CB  1 
ATOM   21341 C CG1 . ILE G 1 310 ? 37.620  11.959  57.114  1.00 23.86  ? 310 ILE G CG1 1 
ATOM   21342 C CG2 . ILE G 1 310 ? 38.733  11.309  59.285  1.00 22.78  ? 310 ILE G CG2 1 
ATOM   21343 C CD1 . ILE G 1 310 ? 36.412  12.537  57.809  1.00 25.48  ? 310 ILE G CD1 1 
ATOM   21344 N N   . GLU G 1 311 ? 41.661  13.583  58.774  1.00 22.85  ? 311 GLU G N   1 
ATOM   21345 C CA  . GLU G 1 311 ? 42.750  13.740  59.723  1.00 25.01  ? 311 GLU G CA  1 
ATOM   21346 C C   . GLU G 1 311 ? 42.761  15.148  60.303  1.00 27.38  ? 311 GLU G C   1 
ATOM   21347 O O   . GLU G 1 311 ? 43.125  15.346  61.469  1.00 24.53  ? 311 GLU G O   1 
ATOM   21348 C CB  . GLU G 1 311 ? 44.073  13.411  59.034  1.00 26.27  ? 311 GLU G CB  1 
ATOM   21349 C CG  . GLU G 1 311 ? 45.300  13.725  59.833  1.00 30.91  ? 311 GLU G CG  1 
ATOM   21350 C CD  . GLU G 1 311 ? 45.314  12.988  61.143  1.00 36.46  ? 311 GLU G CD  1 
ATOM   21351 O OE1 . GLU G 1 311 ? 44.855  11.816  61.158  1.00 32.16  ? 311 GLU G OE1 1 
ATOM   21352 O OE2 . GLU G 1 311 ? 45.756  13.594  62.149  1.00 36.66  ? 311 GLU G OE2 1 
ATOM   21353 N N   . MET G 1 312 ? 42.316  16.130  59.525  1.00 27.02  ? 312 MET G N   1 
ATOM   21354 C CA  . MET G 1 312 ? 42.241  17.475  60.067  1.00 22.91  ? 312 MET G CA  1 
ATOM   21355 C C   . MET G 1 312 ? 41.126  17.599  61.094  1.00 24.69  ? 312 MET G C   1 
ATOM   21356 O O   . MET G 1 312 ? 41.276  18.321  62.088  1.00 23.81  ? 312 MET G O   1 
ATOM   21357 C CB  . MET G 1 312 ? 42.037  18.496  58.964  1.00 25.33  ? 312 MET G CB  1 
ATOM   21358 C CG  . MET G 1 312 ? 41.798  19.865  59.547  1.00 27.67  ? 312 MET G CG  1 
ATOM   21359 S SD  . MET G 1 312 ? 40.616  20.762  58.566  1.00 49.42  ? 312 MET G SD  1 
ATOM   21360 C CE  . MET G 1 312 ? 41.747  21.556  57.434  1.00 31.77  ? 312 MET G CE  1 
ATOM   21361 N N   . ILE G 1 313 ? 39.994  16.919  60.894  1.00 20.88  ? 313 ILE G N   1 
ATOM   21362 C CA  . ILE G 1 313 ? 39.008  17.076  61.952  1.00 26.16  ? 313 ILE G CA  1 
ATOM   21363 C C   . ILE G 1 313 ? 39.464  16.332  63.206  1.00 26.05  ? 313 ILE G C   1 
ATOM   21364 O O   . ILE G 1 313 ? 39.118  16.736  64.323  1.00 24.04  ? 313 ILE G O   1 
ATOM   21365 C CB  . ILE G 1 313 ? 37.586  16.688  61.506  1.00 29.60  ? 313 ILE G CB  1 
ATOM   21366 C CG1 . ILE G 1 313 ? 37.602  15.544  60.537  1.00 28.15  ? 313 ILE G CG1 1 
ATOM   21367 C CG2 . ILE G 1 313 ? 36.865  17.915  60.794  1.00 24.00  ? 313 ILE G CG2 1 
ATOM   21368 C CD1 . ILE G 1 313 ? 36.543  15.697  59.504  1.00 27.18  ? 313 ILE G CD1 1 
ATOM   21369 N N   . ARG G 1 314 ? 40.301  15.294  63.064  1.00 22.76  ? 314 ARG G N   1 
ATOM   21370 C CA  . ARG G 1 314 ? 40.902  14.686  64.251  1.00 26.63  ? 314 ARG G CA  1 
ATOM   21371 C C   . ARG G 1 314 ? 41.842  15.656  64.952  1.00 24.66  ? 314 ARG G C   1 
ATOM   21372 O O   . ARG G 1 314 ? 41.907  15.686  66.187  1.00 26.47  ? 314 ARG G O   1 
ATOM   21373 C CB  . ARG G 1 314 ? 41.662  13.415  63.895  1.00 23.69  ? 314 ARG G CB  1 
ATOM   21374 C CG  . ARG G 1 314 ? 42.000  12.564  65.107  1.00 25.68  ? 314 ARG G CG  1 
ATOM   21375 C CD  . ARG G 1 314 ? 42.572  11.200  64.701  1.00 24.84  ? 314 ARG G CD  1 
ATOM   21376 N NE  . ARG G 1 314 ? 43.957  11.360  64.289  1.00 29.73  ? 314 ARG G NE  1 
ATOM   21377 C CZ  . ARG G 1 314 ? 44.974  11.485  65.131  1.00 31.11  ? 314 ARG G CZ  1 
ATOM   21378 N NH1 . ARG G 1 314 ? 44.802  11.406  66.441  1.00 30.87  ? 314 ARG G NH1 1 
ATOM   21379 N NH2 . ARG G 1 314 ? 46.194  11.693  64.648  1.00 33.05  ? 314 ARG G NH2 1 
ATOM   21380 N N   . THR G 1 315 ? 42.596  16.433  64.174  1.00 26.23  ? 315 THR G N   1 
ATOM   21381 C CA  . THR G 1 315 ? 43.450  17.478  64.733  1.00 27.04  ? 315 THR G CA  1 
ATOM   21382 C C   . THR G 1 315 ? 42.633  18.531  65.475  1.00 27.48  ? 315 THR G C   1 
ATOM   21383 O O   . THR G 1 315 ? 43.044  19.010  66.535  1.00 34.47  ? 315 THR G O   1 
ATOM   21384 C CB  . THR G 1 315 ? 44.269  18.118  63.611  1.00 26.68  ? 315 THR G CB  1 
ATOM   21385 O OG1 . THR G 1 315 ? 45.084  17.117  62.995  1.00 28.67  ? 315 THR G OG1 1 
ATOM   21386 C CG2 . THR G 1 315 ? 45.180  19.210  64.159  1.00 29.78  ? 315 THR G CG2 1 
ATOM   21387 N N   . ILE G 1 316 ? 41.480  18.913  64.930  1.00 27.13  ? 316 ILE G N   1 
ATOM   21388 C CA  . ILE G 1 316 ? 40.611  19.866  65.609  1.00 23.28  ? 316 ILE G CA  1 
ATOM   21389 C C   . ILE G 1 316 ? 40.160  19.331  66.963  1.00 28.77  ? 316 ILE G C   1 
ATOM   21390 O O   . ILE G 1 316 ? 39.806  20.106  67.863  1.00 29.24  ? 316 ILE G O   1 
ATOM   21391 C CB  . ILE G 1 316 ? 39.411  20.204  64.712  1.00 20.98  ? 316 ILE G CB  1 
ATOM   21392 C CG1 . ILE G 1 316 ? 39.877  20.968  63.473  1.00 33.41  ? 316 ILE G CG1 1 
ATOM   21393 C CG2 . ILE G 1 316 ? 38.410  21.047  65.459  1.00 27.85  ? 316 ILE G CG2 1 
ATOM   21394 C CD1 . ILE G 1 316 ? 38.755  21.272  62.470  1.00 24.37  ? 316 ILE G CD1 1 
ATOM   21395 N N   . GLY G 1 317 ? 40.154  18.016  67.142  1.00 25.61  ? 317 GLY G N   1 
ATOM   21396 C CA  . GLY G 1 317 ? 39.801  17.446  68.427  1.00 25.78  ? 317 GLY G CA  1 
ATOM   21397 C C   . GLY G 1 317 ? 38.598  16.526  68.426  1.00 31.26  ? 317 GLY G C   1 
ATOM   21398 O O   . GLY G 1 317 ? 38.238  16.017  69.501  1.00 26.32  ? 317 GLY G O   1 
ATOM   21399 N N   . TYR G 1 318 ? 37.970  16.253  67.277  1.00 28.28  ? 318 TYR G N   1 
ATOM   21400 C CA  . TYR G 1 318 ? 36.848  15.324  67.251  1.00 28.12  ? 318 TYR G CA  1 
ATOM   21401 C C   . TYR G 1 318 ? 37.300  13.901  67.579  1.00 26.93  ? 318 TYR G C   1 
ATOM   21402 O O   . TYR G 1 318 ? 38.290  13.412  67.042  1.00 28.36  ? 318 TYR G O   1 
ATOM   21403 C CB  . TYR G 1 318 ? 36.160  15.325  65.886  1.00 25.97  ? 318 TYR G CB  1 
ATOM   21404 C CG  . TYR G 1 318 ? 35.010  14.367  65.920  1.00 25.00  ? 318 TYR G CG  1 
ATOM   21405 C CD1 . TYR G 1 318 ? 33.969  14.538  66.837  1.00 24.45  ? 318 TYR G CD1 1 
ATOM   21406 C CD2 . TYR G 1 318 ? 34.985  13.252  65.104  1.00 26.46  ? 318 TYR G CD2 1 
ATOM   21407 C CE1 . TYR G 1 318 ? 32.910  13.632  66.901  1.00 24.55  ? 318 TYR G CE1 1 
ATOM   21408 C CE2 . TYR G 1 318 ? 33.940  12.342  65.164  1.00 23.81  ? 318 TYR G CE2 1 
ATOM   21409 C CZ  . TYR G 1 318 ? 32.907  12.537  66.059  1.00 27.46  ? 318 TYR G CZ  1 
ATOM   21410 O OH  . TYR G 1 318 ? 31.871  11.627  66.108  1.00 25.35  ? 318 TYR G OH  1 
ATOM   21411 N N   . ARG G 1 319 ? 36.584  13.239  68.468  1.00 25.74  ? 319 ARG G N   1 
ATOM   21412 C CA  . ARG G 1 319 ? 36.838  11.843  68.782  1.00 27.98  ? 319 ARG G CA  1 
ATOM   21413 C C   . ARG G 1 319 ? 35.536  11.074  68.601  1.00 24.67  ? 319 ARG G C   1 
ATOM   21414 O O   . ARG G 1 319 ? 34.472  11.579  68.955  1.00 28.78  ? 319 ARG G O   1 
ATOM   21415 C CB  . ARG G 1 319 ? 37.383  11.689  70.208  1.00 29.64  ? 319 ARG G CB  1 
ATOM   21416 C CG  . ARG G 1 319 ? 38.657  12.493  70.500  1.00 25.71  ? 319 ARG G CG  1 
ATOM   21417 C CD  . ARG G 1 319 ? 39.887  11.811  69.936  1.00 24.19  ? 319 ARG G CD  1 
ATOM   21418 N NE  . ARG G 1 319 ? 41.104  12.585  70.161  1.00 26.85  ? 319 ARG G NE  1 
ATOM   21419 C CZ  . ARG G 1 319 ? 41.513  13.586  69.389  1.00 27.19  ? 319 ARG G CZ  1 
ATOM   21420 N NH1 . ARG G 1 319 ? 40.795  14.003  68.351  1.00 25.31  ? 319 ARG G NH1 1 
ATOM   21421 N NH2 . ARG G 1 319 ? 42.657  14.199  69.678  1.00 29.02  ? 319 ARG G NH2 1 
ATOM   21422 N N   . GLY G 1 320 ? 35.617  9.873   68.009  1.00 30.19  ? 320 GLY G N   1 
ATOM   21423 C CA  . GLY G 1 320 ? 34.443  9.061   67.730  1.00 22.64  ? 320 GLY G CA  1 
ATOM   21424 C C   . GLY G 1 320 ? 34.194  8.787   66.253  1.00 24.36  ? 320 GLY G C   1 
ATOM   21425 O O   . GLY G 1 320 ? 35.105  8.894   65.431  1.00 23.72  ? 320 GLY G O   1 
ATOM   21426 N N   . TYR G 1 321 ? 32.964  8.437   65.895  1.00 19.95  ? 321 TYR G N   1 
ATOM   21427 C CA  . TYR G 1 321 ? 32.647  8.042   64.530  1.00 20.36  ? 321 TYR G CA  1 
ATOM   21428 C C   . TYR G 1 321 ? 32.314  9.243   63.656  1.00 20.15  ? 321 TYR G C   1 
ATOM   21429 O O   . TYR G 1 321 ? 31.525  10.109  64.040  1.00 20.71  ? 321 TYR G O   1 
ATOM   21430 C CB  . TYR G 1 321 ? 31.493  7.039   64.531  1.00 21.53  ? 321 TYR G CB  1 
ATOM   21431 C CG  . TYR G 1 321 ? 31.893  5.749   65.214  1.00 21.87  ? 321 TYR G CG  1 
ATOM   21432 C CD1 . TYR G 1 321 ? 32.604  4.764   64.532  1.00 23.71  ? 321 TYR G CD1 1 
ATOM   21433 C CD2 . TYR G 1 321 ? 31.598  5.536   66.542  1.00 20.60  ? 321 TYR G CD2 1 
ATOM   21434 C CE1 . TYR G 1 321 ? 32.997  3.588   65.173  1.00 22.17  ? 321 TYR G CE1 1 
ATOM   21435 C CE2 . TYR G 1 321 ? 31.977  4.380   67.180  1.00 23.69  ? 321 TYR G CE2 1 
ATOM   21436 C CZ  . TYR G 1 321 ? 32.679  3.415   66.500  1.00 22.12  ? 321 TYR G CZ  1 
ATOM   21437 O OH  . TYR G 1 321 ? 33.043  2.269   67.159  1.00 26.47  ? 321 TYR G OH  1 
ATOM   21438 N N   . VAL G 1 322 ? 32.895  9.273   62.464  1.00 17.21  ? 322 VAL G N   1 
ATOM   21439 C CA  . VAL G 1 322 ? 32.627  10.341  61.510  1.00 22.43  ? 322 VAL G CA  1 
ATOM   21440 C C   . VAL G 1 322 ? 32.667  9.733   60.115  1.00 24.65  ? 322 VAL G C   1 
ATOM   21441 O O   . VAL G 1 322 ? 33.433  8.796   59.849  1.00 20.76  ? 322 VAL G O   1 
ATOM   21442 C CB  . VAL G 1 322 ? 33.639  11.507  61.653  1.00 22.13  ? 322 VAL G CB  1 
ATOM   21443 C CG1 . VAL G 1 322 ? 35.062  11.027  61.405  1.00 20.05  ? 322 VAL G CG1 1 
ATOM   21444 C CG2 . VAL G 1 322 ? 33.319  12.636  60.685  1.00 20.61  ? 322 VAL G CG2 1 
ATOM   21445 N N   . ASN G 1 323 ? 31.813  10.245  59.230  1.00 21.25  ? 323 ASN G N   1 
ATOM   21446 C CA  . ASN G 1 323 ? 31.836  9.855   57.838  1.00 20.49  ? 323 ASN G CA  1 
ATOM   21447 C C   . ASN G 1 323 ? 31.794  11.099  56.966  1.00 27.32  ? 323 ASN G C   1 
ATOM   21448 O O   . ASN G 1 323 ? 31.447  12.193  57.420  1.00 24.78  ? 323 ASN G O   1 
ATOM   21449 C CB  . ASN G 1 323 ? 30.681  8.921   57.481  1.00 22.02  ? 323 ASN G CB  1 
ATOM   21450 C CG  . ASN G 1 323 ? 29.376  9.663   57.258  1.00 30.88  ? 323 ASN G CG  1 
ATOM   21451 O OD1 . ASN G 1 323 ? 28.674  10.039  58.214  1.00 28.46  ? 323 ASN G OD1 1 
ATOM   21452 N ND2 . ASN G 1 323 ? 29.034  9.868   55.989  1.00 28.01  ? 323 ASN G ND2 1 
ATOM   21453 N N   . ILE G 1 324 ? 32.185  10.906  55.707  1.00 25.01  ? 324 ILE G N   1 
ATOM   21454 C CA  . ILE G 1 324 ? 32.261  11.955  54.699  1.00 24.43  ? 324 ILE G CA  1 
ATOM   21455 C C   . ILE G 1 324 ? 31.751  11.346  53.404  1.00 23.73  ? 324 ILE G C   1 
ATOM   21456 O O   . ILE G 1 324 ? 32.149  10.237  53.040  1.00 24.77  ? 324 ILE G O   1 
ATOM   21457 C CB  . ILE G 1 324 ? 33.706  12.485  54.553  1.00 24.98  ? 324 ILE G CB  1 
ATOM   21458 C CG1 . ILE G 1 324 ? 33.822  13.554  53.461  1.00 22.03  ? 324 ILE G CG1 1 
ATOM   21459 C CG2 . ILE G 1 324 ? 34.701  11.329  54.320  1.00 23.17  ? 324 ILE G CG2 1 
ATOM   21460 C CD1 . ILE G 1 324 ? 35.250  14.172  53.378  1.00 19.23  ? 324 ILE G CD1 1 
ATOM   21461 N N   . ASP G 1 325 ? 30.812  12.012  52.745  1.00 29.41  ? 325 ASP G N   1 
ATOM   21462 C CA  . ASP G 1 325 ? 30.252  11.452  51.520  1.00 28.44  ? 325 ASP G CA  1 
ATOM   21463 C C   . ASP G 1 325 ? 30.731  12.242  50.314  1.00 26.30  ? 325 ASP G C   1 
ATOM   21464 O O   . ASP G 1 325 ? 31.036  13.435  50.410  1.00 30.75  ? 325 ASP G O   1 
ATOM   21465 C CB  . ASP G 1 325 ? 28.719  11.408  51.564  1.00 28.17  ? 325 ASP G CB  1 
ATOM   21466 C CG  . ASP G 1 325 ? 28.099  12.753  51.369  1.00 30.59  ? 325 ASP G CG  1 
ATOM   21467 O OD1 . ASP G 1 325 ? 28.006  13.475  52.369  1.00 39.08  ? 325 ASP G OD1 1 
ATOM   21468 O OD2 . ASP G 1 325 ? 27.696  13.089  50.228  1.00 36.55  ? 325 ASP G OD2 1 
ATOM   21469 N N   . GLY G 1 326 ? 30.808  11.558  49.178  1.00 26.31  ? 326 GLY G N   1 
ATOM   21470 C CA  . GLY G 1 326 ? 31.361  12.157  47.985  1.00 29.40  ? 326 GLY G CA  1 
ATOM   21471 C C   . GLY G 1 326 ? 30.743  11.558  46.745  1.00 26.19  ? 326 GLY G C   1 
ATOM   21472 O O   . GLY G 1 326 ? 29.850  10.714  46.822  1.00 31.08  ? 326 GLY G O   1 
ATOM   21473 N N   . ILE G 1 327 ? 31.213  12.023  45.587  1.00 28.61  ? 327 ILE G N   1 
ATOM   21474 C CA  . ILE G 1 327 ? 30.785  11.489  44.297  1.00 30.76  ? 327 ILE G CA  1 
ATOM   21475 C C   . ILE G 1 327 ? 31.976  11.446  43.351  1.00 26.16  ? 327 ILE G C   1 
ATOM   21476 O O   . ILE G 1 327 ? 32.883  12.276  43.426  1.00 31.85  ? 327 ILE G O   1 
ATOM   21477 C CB  . ILE G 1 327 ? 29.654  12.317  43.642  1.00 28.25  ? 327 ILE G CB  1 
ATOM   21478 C CG1 . ILE G 1 327 ? 30.182  13.709  43.272  1.00 26.31  ? 327 ILE G CG1 1 
ATOM   21479 C CG2 . ILE G 1 327 ? 28.456  12.397  44.539  1.00 29.49  ? 327 ILE G CG2 1 
ATOM   21480 C CD1 . ILE G 1 327 ? 29.150  14.618  42.636  1.00 26.14  ? 327 ILE G CD1 1 
ATOM   21481 N N   . VAL G 1 328 ? 31.959  10.474  42.447  1.00 27.55  ? 328 VAL G N   1 
ATOM   21482 C CA  . VAL G 1 328 ? 32.855  10.434  41.300  1.00 34.34  ? 328 VAL G CA  1 
ATOM   21483 C C   . VAL G 1 328 ? 32.028  10.713  40.051  1.00 37.27  ? 328 VAL G C   1 
ATOM   21484 O O   . VAL G 1 328 ? 30.906  10.207  39.917  1.00 36.79  ? 328 VAL G O   1 
ATOM   21485 C CB  . VAL G 1 328 ? 33.575  9.072   41.192  1.00 36.40  ? 328 VAL G CB  1 
ATOM   21486 C CG1 . VAL G 1 328 ? 34.639  9.118   40.103  1.00 36.43  ? 328 VAL G CG1 1 
ATOM   21487 C CG2 . VAL G 1 328 ? 34.204  8.689   42.517  1.00 30.01  ? 328 VAL G CG2 1 
ATOM   21488 N N   . LEU G 1 329 ? 32.569  11.519  39.138  1.00 39.04  ? 329 LEU G N   1 
ATOM   21489 C CA  . LEU G 1 329 ? 31.919  11.760  37.854  1.00 41.66  ? 329 LEU G CA  1 
ATOM   21490 C C   . LEU G 1 329 ? 32.554  10.892  36.771  1.00 43.01  ? 329 LEU G C   1 
ATOM   21491 O O   . LEU G 1 329 ? 33.599  10.273  36.974  1.00 40.92  ? 329 LEU G O   1 
ATOM   21492 C CB  . LEU G 1 329 ? 31.999  13.238  37.444  1.00 39.34  ? 329 LEU G CB  1 
ATOM   21493 C CG  . LEU G 1 329 ? 31.516  14.381  38.345  1.00 42.47  ? 329 LEU G CG  1 
ATOM   21494 C CD1 . LEU G 1 329 ? 31.591  15.706  37.588  1.00 36.73  ? 329 LEU G CD1 1 
ATOM   21495 C CD2 . LEU G 1 329 ? 30.115  14.143  38.893  1.00 42.13  ? 329 LEU G CD2 1 
ATOM   21496 N N   . ASP G 1 330 ? 31.924  10.886  35.588  1.00 44.80  ? 330 ASP G N   1 
ATOM   21497 C CA  . ASP G 1 330 ? 32.488  10.159  34.451  1.00 46.57  ? 330 ASP G CA  1 
ATOM   21498 C C   . ASP G 1 330 ? 33.827  10.733  34.015  1.00 41.32  ? 330 ASP G C   1 
ATOM   21499 O O   . ASP G 1 330 ? 34.728  9.985   33.622  1.00 49.18  ? 330 ASP G O   1 
ATOM   21500 C CB  . ASP G 1 330 ? 31.516  10.173  33.284  1.00 51.22  ? 330 ASP G CB  1 
ATOM   21501 C CG  . ASP G 1 330 ? 30.144  9.732   33.688  1.00 50.61  ? 330 ASP G CG  1 
ATOM   21502 O OD1 . ASP G 1 330 ? 29.489  10.492  34.432  1.00 54.47  ? 330 ASP G OD1 1 
ATOM   21503 O OD2 . ASP G 1 330 ? 29.732  8.624   33.271  1.00 55.64  ? 330 ASP G OD2 1 
ATOM   21504 N N   . ASP G 1 331 ? 33.986  12.033  34.072  1.00 38.76  ? 331 ASP G N   1 
ATOM   21505 C CA  . ASP G 1 331 ? 35.309  12.518  33.697  1.00 45.16  ? 331 ASP G CA  1 
ATOM   21506 C C   . ASP G 1 331 ? 36.404  12.232  34.782  1.00 43.23  ? 331 ASP G C   1 
ATOM   21507 O O   . ASP G 1 331 ? 37.506  12.794  34.680  1.00 41.93  ? 331 ASP G O   1 
ATOM   21508 C CB  . ASP G 1 331 ? 35.239  14.013  33.370  1.00 48.22  ? 331 ASP G CB  1 
ATOM   21509 C CG  . ASP G 1 331 ? 34.461  14.806  34.403  1.00 49.29  ? 331 ASP G CG  1 
ATOM   21510 O OD1 . ASP G 1 331 ? 34.471  14.417  35.593  1.00 47.85  ? 331 ASP G OD1 1 
ATOM   21511 O OD2 . ASP G 1 331 ? 33.836  15.818  34.022  1.00 49.83  ? 331 ASP G OD2 1 
ATOM   21512 N N   . GLY G 1 332 ? 36.125  11.384  35.777  1.00 40.93  ? 332 GLY G N   1 
ATOM   21513 C CA  . GLY G 1 332 ? 37.072  11.048  36.826  1.00 45.90  ? 332 GLY G CA  1 
ATOM   21514 C C   . GLY G 1 332 ? 37.102  11.985  38.025  1.00 40.37  ? 332 GLY G C   1 
ATOM   21515 O O   . GLY G 1 332 ? 37.798  11.687  39.008  1.00 37.98  ? 332 GLY G O   1 
ATOM   21516 N N   . ARG G 1 333 ? 36.374  13.098  37.986  1.00 36.56  ? 333 ARG G N   1 
ATOM   21517 C CA  . ARG G 1 333 ? 36.478  14.098  39.037  1.00 40.24  ? 333 ARG G CA  1 
ATOM   21518 C C   . ARG G 1 333 ? 35.747  13.655  40.302  1.00 34.20  ? 333 ARG G C   1 
ATOM   21519 O O   . ARG G 1 333 ? 34.631  13.125  40.252  1.00 35.22  ? 333 ARG G O   1 
ATOM   21520 C CB  . ARG G 1 333 ? 35.934  15.447  38.558  1.00 39.03  ? 333 ARG G CB  1 
ATOM   21521 C CG  . ARG G 1 333 ? 36.980  16.355  37.890  1.00 43.42  ? 333 ARG G CG  1 
ATOM   21522 C CD  . ARG G 1 333 ? 36.322  17.616  37.346  1.00 40.75  ? 333 ARG G CD  1 
ATOM   21523 N NE  . ARG G 1 333 ? 35.187  17.272  36.501  1.00 45.53  ? 333 ARG G NE  1 
ATOM   21524 C CZ  . ARG G 1 333 ? 34.176  18.083  36.230  1.00 47.09  ? 333 ARG G CZ  1 
ATOM   21525 N NH1 . ARG G 1 333 ? 34.136  19.320  36.704  1.00 40.47  ? 333 ARG G NH1 1 
ATOM   21526 N NH2 . ARG G 1 333 ? 33.178  17.640  35.468  1.00 45.88  ? 333 ARG G NH2 1 
ATOM   21527 N N   . VAL G 1 334 ? 36.399  13.889  41.434  1.00 25.62  ? 334 VAL G N   1 
ATOM   21528 C CA  . VAL G 1 334 ? 35.896  13.584  42.763  1.00 28.31  ? 334 VAL G CA  1 
ATOM   21529 C C   . VAL G 1 334 ? 35.433  14.872  43.423  1.00 30.60  ? 334 VAL G C   1 
ATOM   21530 O O   . VAL G 1 334 ? 36.136  15.888  43.379  1.00 29.63  ? 334 VAL G O   1 
ATOM   21531 C CB  . VAL G 1 334 ? 37.002  12.922  43.605  1.00 29.67  ? 334 VAL G CB  1 
ATOM   21532 C CG1 . VAL G 1 334 ? 36.529  12.726  45.042  1.00 28.47  ? 334 VAL G CG1 1 
ATOM   21533 C CG2 . VAL G 1 334 ? 37.447  11.623  42.964  1.00 27.03  ? 334 VAL G CG2 1 
ATOM   21534 N N   . PHE G 1 335 ? 34.259  14.834  44.052  1.00 30.60  ? 335 PHE G N   1 
ATOM   21535 C CA  . PHE G 1 335 ? 33.813  15.898  44.941  1.00 31.45  ? 335 PHE G CA  1 
ATOM   21536 C C   . PHE G 1 335 ? 33.366  15.289  46.269  1.00 29.75  ? 335 PHE G C   1 
ATOM   21537 O O   . PHE G 1 335 ? 32.823  14.183  46.301  1.00 25.56  ? 335 PHE G O   1 
ATOM   21538 C CB  . PHE G 1 335 ? 32.661  16.709  44.335  1.00 32.98  ? 335 PHE G CB  1 
ATOM   21539 C CG  . PHE G 1 335 ? 33.034  17.514  43.110  1.00 33.07  ? 335 PHE G CG  1 
ATOM   21540 C CD1 . PHE G 1 335 ? 34.023  18.485  43.165  1.00 34.40  ? 335 PHE G CD1 1 
ATOM   21541 C CD2 . PHE G 1 335 ? 32.355  17.324  41.913  1.00 37.89  ? 335 PHE G CD2 1 
ATOM   21542 C CE1 . PHE G 1 335 ? 34.345  19.231  42.040  1.00 37.14  ? 335 PHE G CE1 1 
ATOM   21543 C CE2 . PHE G 1 335 ? 32.670  18.065  40.790  1.00 34.13  ? 335 PHE G CE2 1 
ATOM   21544 C CZ  . PHE G 1 335 ? 33.660  19.012  40.849  1.00 33.98  ? 335 PHE G CZ  1 
ATOM   21545 N N   . PHE G 1 336 ? 33.615  16.001  47.366  1.00 28.74  ? 336 PHE G N   1 
ATOM   21546 C CA  . PHE G 1 336 ? 33.053  15.650  48.657  1.00 27.22  ? 336 PHE G CA  1 
ATOM   21547 C C   . PHE G 1 336 ? 31.995  16.680  49.001  1.00 30.56  ? 336 PHE G C   1 
ATOM   21548 O O   . PHE G 1 336 ? 32.152  17.864  48.681  1.00 31.95  ? 336 PHE G O   1 
ATOM   21549 C CB  . PHE G 1 336 ? 34.132  15.565  49.737  1.00 25.66  ? 336 PHE G CB  1 
ATOM   21550 C CG  . PHE G 1 336 ? 35.125  14.472  49.487  1.00 23.64  ? 336 PHE G CG  1 
ATOM   21551 C CD1 . PHE G 1 336 ? 34.841  13.158  49.849  1.00 26.13  ? 336 PHE G CD1 1 
ATOM   21552 C CD2 . PHE G 1 336 ? 36.315  14.738  48.843  1.00 22.83  ? 336 PHE G CD2 1 
ATOM   21553 C CE1 . PHE G 1 336 ? 35.755  12.130  49.605  1.00 23.31  ? 336 PHE G CE1 1 
ATOM   21554 C CE2 . PHE G 1 336 ? 37.241  13.709  48.585  1.00 26.69  ? 336 PHE G CE2 1 
ATOM   21555 C CZ  . PHE G 1 336 ? 36.959  12.411  48.971  1.00 24.69  ? 336 PHE G CZ  1 
ATOM   21556 N N   . HIS G 1 337 ? 30.908  16.212  49.626  1.00 27.97  ? 337 HIS G N   1 
ATOM   21557 C CA  . HIS G 1 337 ? 29.698  16.995  49.856  1.00 28.04  ? 337 HIS G CA  1 
ATOM   21558 C C   . HIS G 1 337 ? 29.530  17.465  51.290  1.00 30.98  ? 337 HIS G C   1 
ATOM   21559 O O   . HIS G 1 337 ? 29.212  18.635  51.513  1.00 33.90  ? 337 HIS G O   1 
ATOM   21560 C CB  . HIS G 1 337 ? 28.460  16.184  49.463  1.00 28.01  ? 337 HIS G CB  1 
ATOM   21561 C CG  . HIS G 1 337 ? 28.334  15.977  47.999  1.00 30.19  ? 337 HIS G CG  1 
ATOM   21562 N ND1 . HIS G 1 337 ? 28.869  16.854  47.081  1.00 36.20  ? 337 HIS G ND1 1 
ATOM   21563 C CD2 . HIS G 1 337 ? 27.716  15.009  47.284  1.00 32.87  ? 337 HIS G CD2 1 
ATOM   21564 C CE1 . HIS G 1 337 ? 28.595  16.429  45.860  1.00 36.85  ? 337 HIS G CE1 1 
ATOM   21565 N NE2 . HIS G 1 337 ? 27.893  15.314  45.956  1.00 40.89  ? 337 HIS G NE2 1 
ATOM   21566 N N   . GLU G 1 338 ? 29.660  16.571  52.265  1.00 27.96  ? 338 GLU G N   1 
ATOM   21567 C CA  . GLU G 1 338 ? 29.508  16.949  53.664  1.00 32.96  ? 338 GLU G CA  1 
ATOM   21568 C C   . GLU G 1 338 ? 30.130  15.872  54.538  1.00 30.53  ? 338 GLU G C   1 
ATOM   21569 O O   . GLU G 1 338 ? 30.436  14.765  54.075  1.00 25.72  ? 338 GLU G O   1 
ATOM   21570 C CB  . GLU G 1 338 ? 28.032  17.180  54.033  1.00 35.25  ? 338 GLU G CB  1 
ATOM   21571 C CG  . GLU G 1 338 ? 27.114  15.972  53.935  1.00 35.04  ? 338 GLU G CG  1 
ATOM   21572 C CD  . GLU G 1 338 ? 25.631  16.376  53.863  1.00 39.70  ? 338 GLU G CD  1 
ATOM   21573 O OE1 . GLU G 1 338 ? 25.124  16.694  52.757  1.00 39.23  ? 338 GLU G OE1 1 
ATOM   21574 O OE2 . GLU G 1 338 ? 24.976  16.398  54.932  1.00 38.98  ? 338 GLU G OE2 1 
ATOM   21575 N N   . ILE G 1 339 ? 30.312  16.227  55.818  1.00 24.64  ? 339 ILE G N   1 
ATOM   21576 C CA  . ILE G 1 339 ? 30.730  15.310  56.873  1.00 22.78  ? 339 ILE G CA  1 
ATOM   21577 C C   . ILE G 1 339 ? 29.654  15.263  57.956  1.00 29.35  ? 339 ILE G C   1 
ATOM   21578 O O   . ILE G 1 339 ? 28.896  16.218  58.166  1.00 31.16  ? 339 ILE G O   1 
ATOM   21579 C CB  . ILE G 1 339 ? 32.072  15.712  57.510  1.00 24.68  ? 339 ILE G CB  1 
ATOM   21580 C CG1 . ILE G 1 339 ? 32.020  17.163  57.982  1.00 23.13  ? 339 ILE G CG1 1 
ATOM   21581 C CG2 . ILE G 1 339 ? 33.252  15.455  56.574  1.00 23.71  ? 339 ILE G CG2 1 
ATOM   21582 C CD1 . ILE G 1 339 ? 32.902  17.406  59.180  1.00 26.65  ? 339 ILE G CD1 1 
ATOM   21583 N N   . ASN G 1 340 ? 29.622  14.143  58.676  1.00 27.29  ? 340 ASN G N   1 
ATOM   21584 C CA  . ASN G 1 340 ? 28.686  13.927  59.775  1.00 27.59  ? 340 ASN G CA  1 
ATOM   21585 C C   . ASN G 1 340 ? 29.458  13.317  60.937  1.00 29.18  ? 340 ASN G C   1 
ATOM   21586 O O   . ASN G 1 340 ? 29.963  12.195  60.811  1.00 22.61  ? 340 ASN G O   1 
ATOM   21587 C CB  . ASN G 1 340 ? 27.545  12.990  59.362  1.00 29.77  ? 340 ASN G CB  1 
ATOM   21588 C CG  . ASN G 1 340 ? 26.535  13.650  58.432  1.00 33.88  ? 340 ASN G CG  1 
ATOM   21589 O OD1 . ASN G 1 340 ? 25.924  14.664  58.775  1.00 37.54  ? 340 ASN G OD1 1 
ATOM   21590 N ND2 . ASN G 1 340 ? 26.327  13.048  57.262  1.00 30.41  ? 340 ASN G ND2 1 
ATOM   21591 N N   . ALA G 1 341 ? 29.536  14.034  62.067  1.00 22.54  ? 341 ALA G N   1 
ATOM   21592 C CA  . ALA G 1 341 ? 30.257  13.541  63.242  1.00 25.29  ? 341 ALA G CA  1 
ATOM   21593 C C   . ALA G 1 341 ? 29.277  12.851  64.197  1.00 27.46  ? 341 ALA G C   1 
ATOM   21594 O O   . ALA G 1 341 ? 28.823  13.416  65.198  1.00 23.07  ? 341 ALA G O   1 
ATOM   21595 C CB  . ALA G 1 341 ? 31.020  14.673  63.916  1.00 22.75  ? 341 ALA G CB  1 
ATOM   21596 N N   . ARG G 1 342 ? 28.983  11.583  63.887  1.00 24.57  ? 342 ARG G N   1 
ATOM   21597 C CA  . ARG G 1 342 ? 28.066  10.723  64.638  1.00 28.76  ? 342 ARG G CA  1 
ATOM   21598 C C   . ARG G 1 342 ? 27.971  9.391   63.904  1.00 25.00  ? 342 ARG G C   1 
ATOM   21599 O O   . ARG G 1 342 ? 28.616  9.239   62.863  1.00 26.50  ? 342 ARG G O   1 
ATOM   21600 C CB  . ARG G 1 342 ? 26.679  11.360  64.777  1.00 27.73  ? 342 ARG G CB  1 
ATOM   21601 C CG  . ARG G 1 342 ? 26.133  11.836  63.468  1.00 27.92  ? 342 ARG G CG  1 
ATOM   21602 C CD  . ARG G 1 342 ? 24.906  12.719  63.681  1.00 42.25  ? 342 ARG G CD  1 
ATOM   21603 N NE  . ARG G 1 342 ? 24.361  13.138  62.401  1.00 37.16  ? 342 ARG G NE  1 
ATOM   21604 C CZ  . ARG G 1 342 ? 23.884  12.313  61.477  1.00 43.84  ? 342 ARG G CZ  1 
ATOM   21605 N NH1 . ARG G 1 342 ? 23.717  11.022  61.721  1.00 53.98  ? 342 ARG G NH1 1 
ATOM   21606 N NH2 . ARG G 1 342 ? 23.563  12.795  60.275  1.00 53.35  ? 342 ARG G NH2 1 
ATOM   21607 N N   . TRP G 1 343 ? 27.199  8.420   64.412  1.00 23.38  ? 343 TRP G N   1 
ATOM   21608 C CA  . TRP G 1 343 ? 27.043  7.170   63.669  1.00 24.47  ? 343 TRP G CA  1 
ATOM   21609 C C   . TRP G 1 343 ? 26.472  7.481   62.298  1.00 26.86  ? 343 TRP G C   1 
ATOM   21610 O O   . TRP G 1 343 ? 25.529  8.271   62.178  1.00 31.83  ? 343 TRP G O   1 
ATOM   21611 C CB  . TRP G 1 343 ? 26.112  6.183   64.387  1.00 23.61  ? 343 TRP G CB  1 
ATOM   21612 C CG  . TRP G 1 343 ? 26.530  5.805   65.753  1.00 23.93  ? 343 TRP G CG  1 
ATOM   21613 C CD1 . TRP G 1 343 ? 27.774  5.910   66.276  1.00 23.81  ? 343 TRP G CD1 1 
ATOM   21614 C CD2 . TRP G 1 343 ? 25.699  5.266   66.789  1.00 27.96  ? 343 TRP G CD2 1 
ATOM   21615 N NE1 . TRP G 1 343 ? 27.780  5.482   67.584  1.00 29.38  ? 343 TRP G NE1 1 
ATOM   21616 C CE2 . TRP G 1 343 ? 26.520  5.074   67.924  1.00 26.83  ? 343 TRP G CE2 1 
ATOM   21617 C CE3 . TRP G 1 343 ? 24.339  4.931   66.871  1.00 28.94  ? 343 TRP G CE3 1 
ATOM   21618 C CZ2 . TRP G 1 343 ? 26.034  4.553   69.129  1.00 26.51  ? 343 TRP G CZ2 1 
ATOM   21619 C CZ3 . TRP G 1 343 ? 23.852  4.406   68.076  1.00 27.27  ? 343 TRP G CZ3 1 
ATOM   21620 C CH2 . TRP G 1 343 ? 24.703  4.224   69.186  1.00 27.42  ? 343 TRP G CH2 1 
ATOM   21621 N N   . SER G 1 344 ? 27.046  6.887   61.257  1.00 19.66  ? 344 SER G N   1 
ATOM   21622 C CA  . SER G 1 344 ? 26.279  6.852   60.022  1.00 23.07  ? 344 SER G CA  1 
ATOM   21623 C C   . SER G 1 344 ? 25.171  5.808   60.152  1.00 24.41  ? 344 SER G C   1 
ATOM   21624 O O   . SER G 1 344 ? 25.190  4.964   61.040  1.00 23.44  ? 344 SER G O   1 
ATOM   21625 C CB  . SER G 1 344 ? 27.178  6.509   58.843  1.00 26.04  ? 344 SER G CB  1 
ATOM   21626 O OG  . SER G 1 344 ? 27.523  5.138   58.893  1.00 23.17  ? 344 SER G OG  1 
ATOM   21627 N N   . GLY G 1 345 ? 24.214  5.829   59.233  1.00 27.83  ? 345 GLY G N   1 
ATOM   21628 C CA  . GLY G 1 345 ? 23.208  4.778   59.252  1.00 19.76  ? 345 GLY G CA  1 
ATOM   21629 C C   . GLY G 1 345 ? 23.759  3.387   58.977  1.00 26.85  ? 345 GLY G C   1 
ATOM   21630 O O   . GLY G 1 345 ? 23.138  2.394   59.370  1.00 25.51  ? 345 GLY G O   1 
ATOM   21631 N N   . GLY G 1 346 ? 24.908  3.288   58.312  1.00 25.14  ? 346 GLY G N   1 
ATOM   21632 C CA  . GLY G 1 346 ? 25.490  2.003   57.988  1.00 23.19  ? 346 GLY G CA  1 
ATOM   21633 C C   . GLY G 1 346 ? 26.499  1.460   58.982  1.00 24.73  ? 346 GLY G C   1 
ATOM   21634 O O   . GLY G 1 346 ? 26.990  0.334   58.801  1.00 23.56  ? 346 GLY G O   1 
ATOM   21635 N N   . LEU G 1 347 ? 26.834  2.221   60.029  1.00 22.15  ? 347 LEU G N   1 
ATOM   21636 C CA  . LEU G 1 347 ? 27.831  1.751   60.990  1.00 24.75  ? 347 LEU G CA  1 
ATOM   21637 C C   . LEU G 1 347 ? 27.430  0.415   61.620  1.00 24.52  ? 347 LEU G C   1 
ATOM   21638 O O   . LEU G 1 347 ? 28.290  -0.422  61.914  1.00 27.99  ? 347 LEU G O   1 
ATOM   21639 C CB  . LEU G 1 347 ? 28.055  2.823   62.068  1.00 18.39  ? 347 LEU G CB  1 
ATOM   21640 C CG  . LEU G 1 347 ? 29.017  2.441   63.192  1.00 21.73  ? 347 LEU G CG  1 
ATOM   21641 C CD1 . LEU G 1 347 ? 30.377  1.962   62.659  1.00 17.04  ? 347 LEU G CD1 1 
ATOM   21642 C CD2 . LEU G 1 347 ? 29.187  3.586   64.215  1.00 20.28  ? 347 LEU G CD2 1 
ATOM   21643 N N   . ILE G 1 348 ? 26.136  0.184   61.817  1.00 22.71  ? 348 ILE G N   1 
ATOM   21644 C CA  . ILE G 1 348 ? 25.706  -1.093  62.385  1.00 24.54  ? 348 ILE G CA  1 
ATOM   21645 C C   . ILE G 1 348 ? 25.877  -2.217  61.366  1.00 20.60  ? 348 ILE G C   1 
ATOM   21646 O O   . ILE G 1 348 ? 26.277  -3.333  61.714  1.00 23.40  ? 348 ILE G O   1 
ATOM   21647 C CB  . ILE G 1 348 ? 24.252  -0.972  62.883  1.00 22.86  ? 348 ILE G CB  1 
ATOM   21648 C CG1 . ILE G 1 348 ? 23.838  -2.209  63.648  1.00 21.30  ? 348 ILE G CG1 1 
ATOM   21649 C CG2 . ILE G 1 348 ? 23.280  -0.687  61.698  1.00 24.65  ? 348 ILE G CG2 1 
ATOM   21650 C CD1 . ILE G 1 348 ? 24.414  -2.243  65.032  1.00 29.32  ? 348 ILE G CD1 1 
ATOM   21651 N N   . TYR G 1 349 ? 25.584  -1.948  60.096  1.00 20.42  ? 349 TYR G N   1 
ATOM   21652 C CA  . TYR G 1 349 ? 25.783  -2.961  59.065  1.00 23.79  ? 349 TYR G CA  1 
ATOM   21653 C C   . TYR G 1 349 ? 27.223  -3.448  59.051  1.00 24.39  ? 349 TYR G C   1 
ATOM   21654 O O   . TYR G 1 349 ? 27.487  -4.660  59.040  1.00 23.90  ? 349 TYR G O   1 
ATOM   21655 C CB  . TYR G 1 349 ? 25.428  -2.409  57.688  1.00 22.07  ? 349 TYR G CB  1 
ATOM   21656 C CG  . TYR G 1 349 ? 24.050  -1.821  57.529  1.00 29.69  ? 349 TYR G CG  1 
ATOM   21657 C CD1 . TYR G 1 349 ? 22.936  -2.306  58.241  1.00 30.32  ? 349 TYR G CD1 1 
ATOM   21658 C CD2 . TYR G 1 349 ? 23.848  -0.783  56.637  1.00 28.43  ? 349 TYR G CD2 1 
ATOM   21659 C CE1 . TYR G 1 349 ? 21.656  -1.728  58.046  1.00 23.55  ? 349 TYR G CE1 1 
ATOM   21660 C CE2 . TYR G 1 349 ? 22.619  -0.222  56.455  1.00 28.78  ? 349 TYR G CE2 1 
ATOM   21661 C CZ  . TYR G 1 349 ? 21.526  -0.683  57.147  1.00 29.13  ? 349 TYR G CZ  1 
ATOM   21662 O OH  . TYR G 1 349 ? 20.317  -0.065  56.881  1.00 31.63  ? 349 TYR G OH  1 
ATOM   21663 N N   . HIS G 1 350 ? 28.172  -2.504  59.025  1.00 25.43  ? 350 HIS G N   1 
ATOM   21664 C CA  . HIS G 1 350 ? 29.586  -2.853  59.033  1.00 22.79  ? 350 HIS G CA  1 
ATOM   21665 C C   . HIS G 1 350 ? 29.944  -3.645  60.288  1.00 24.26  ? 350 HIS G C   1 
ATOM   21666 O O   . HIS G 1 350 ? 30.799  -4.534  60.236  1.00 22.76  ? 350 HIS G O   1 
ATOM   21667 C CB  . HIS G 1 350 ? 30.426  -1.567  58.904  1.00 23.58  ? 350 HIS G CB  1 
ATOM   21668 C CG  . HIS G 1 350 ? 31.842  -1.700  59.392  1.00 22.65  ? 350 HIS G CG  1 
ATOM   21669 N ND1 . HIS G 1 350 ? 32.816  -2.375  58.686  1.00 25.89  ? 350 HIS G ND1 1 
ATOM   21670 C CD2 . HIS G 1 350 ? 32.444  -1.242  60.512  1.00 22.72  ? 350 HIS G CD2 1 
ATOM   21671 C CE1 . HIS G 1 350 ? 33.957  -2.326  59.351  1.00 24.94  ? 350 HIS G CE1 1 
ATOM   21672 N NE2 . HIS G 1 350 ? 33.759  -1.635  60.459  1.00 25.00  ? 350 HIS G NE2 1 
ATOM   21673 N N   . THR G 1 351 ? 29.273  -3.365  61.409  1.00 25.04  ? 351 THR G N   1 
ATOM   21674 C CA  . THR G 1 351 ? 29.571  -4.063  62.658  1.00 23.38  ? 351 THR G CA  1 
ATOM   21675 C C   . THR G 1 351 ? 29.089  -5.504  62.611  1.00 24.19  ? 351 THR G C   1 
ATOM   21676 O O   . THR G 1 351 ? 29.834  -6.435  62.958  1.00 27.02  ? 351 THR G O   1 
ATOM   21677 C CB  . THR G 1 351 ? 28.908  -3.334  63.828  1.00 25.85  ? 351 THR G CB  1 
ATOM   21678 O OG1 . THR G 1 351 ? 29.128  -1.929  63.695  1.00 26.90  ? 351 THR G OG1 1 
ATOM   21679 C CG2 . THR G 1 351 ? 29.460  -3.818  65.163  1.00 27.81  ? 351 THR G CG2 1 
ATOM   21680 N N   . VAL G 1 352 ? 27.829  -5.702  62.211  1.00 19.43  ? 352 VAL G N   1 
ATOM   21681 C CA  . VAL G 1 352 ? 27.292  -7.043  62.032  1.00 20.01  ? 352 VAL G CA  1 
ATOM   21682 C C   . VAL G 1 352 ? 28.089  -7.787  60.978  1.00 25.24  ? 352 VAL G C   1 
ATOM   21683 O O   . VAL G 1 352 ? 28.390  -8.979  61.132  1.00 22.09  ? 352 VAL G O   1 
ATOM   21684 C CB  . VAL G 1 352 ? 25.795  -6.972  61.669  1.00 20.22  ? 352 VAL G CB  1 
ATOM   21685 C CG1 . VAL G 1 352 ? 25.171  -8.372  61.588  1.00 20.21  ? 352 VAL G CG1 1 
ATOM   21686 C CG2 . VAL G 1 352 ? 25.075  -6.129  62.681  1.00 19.74  ? 352 VAL G CG2 1 
ATOM   21687 N N   . ALA G 1 353 ? 28.446  -7.099  59.888  1.00 26.93  ? 353 ALA G N   1 
ATOM   21688 C CA  . ALA G 1 353 ? 29.273  -7.735  58.867  1.00 19.60  ? 353 ALA G CA  1 
ATOM   21689 C C   . ALA G 1 353 ? 30.584  -8.194  59.466  1.00 21.92  ? 353 ALA G C   1 
ATOM   21690 O O   . ALA G 1 353 ? 31.011  -9.329  59.242  1.00 24.35  ? 353 ALA G O   1 
ATOM   21691 C CB  . ALA G 1 353 ? 29.522  -6.791  57.687  1.00 19.55  ? 353 ALA G CB  1 
ATOM   21692 N N   . GLU G 1 354 ? 31.220  -7.345  60.273  1.00 22.98  ? 354 GLU G N   1 
ATOM   21693 C CA  . GLU G 1 354 ? 32.473  -7.765  60.894  1.00 24.55  ? 354 GLU G CA  1 
ATOM   21694 C C   . GLU G 1 354 ? 32.266  -8.967  61.815  1.00 22.74  ? 354 GLU G C   1 
ATOM   21695 O O   . GLU G 1 354 ? 33.059  -9.908  61.791  1.00 28.00  ? 354 GLU G O   1 
ATOM   21696 C CB  . GLU G 1 354 ? 33.114  -6.599  61.647  1.00 21.89  ? 354 GLU G CB  1 
ATOM   21697 C CG  . GLU G 1 354 ? 33.900  -5.647  60.735  1.00 28.55  ? 354 GLU G CG  1 
ATOM   21698 C CD  . GLU G 1 354 ? 35.033  -4.889  61.453  1.00 34.01  ? 354 GLU G CD  1 
ATOM   21699 O OE1 . GLU G 1 354 ? 34.913  -4.620  62.677  1.00 23.53  ? 354 GLU G OE1 1 
ATOM   21700 O OE2 . GLU G 1 354 ? 36.043  -4.562  60.773  1.00 35.42  ? 354 GLU G OE2 1 
ATOM   21701 N N   . ARG G 1 355 ? 31.201  -8.967  62.621  1.00 25.03  ? 355 ARG G N   1 
ATOM   21702 C CA  . ARG G 1 355 ? 31.033  -10.034 63.609  1.00 25.11  ? 355 ARG G CA  1 
ATOM   21703 C C   . ARG G 1 355 ? 30.663  -11.359 62.949  1.00 28.47  ? 355 ARG G C   1 
ATOM   21704 O O   . ARG G 1 355 ? 31.199  -12.409 63.323  1.00 28.39  ? 355 ARG G O   1 
ATOM   21705 C CB  . ARG G 1 355 ? 29.982  -9.637  64.645  1.00 26.42  ? 355 ARG G CB  1 
ATOM   21706 C CG  . ARG G 1 355 ? 30.338  -8.348  65.396  1.00 28.90  ? 355 ARG G CG  1 
ATOM   21707 C CD  . ARG G 1 355 ? 29.274  -7.976  66.418  1.00 25.63  ? 355 ARG G CD  1 
ATOM   21708 N NE  . ARG G 1 355 ? 29.359  -8.816  67.600  1.00 32.32  ? 355 ARG G NE  1 
ATOM   21709 C CZ  . ARG G 1 355 ? 28.809  -8.533  68.771  1.00 32.39  ? 355 ARG G CZ  1 
ATOM   21710 N NH1 . ARG G 1 355 ? 28.176  -7.390  68.984  1.00 26.32  ? 355 ARG G NH1 1 
ATOM   21711 N NH2 . ARG G 1 355 ? 28.880  -9.431  69.751  1.00 36.08  ? 355 ARG G NH2 1 
ATOM   21712 N N   . LEU G 1 356 ? 29.787  -11.324 61.931  1.00 25.09  ? 356 LEU G N   1 
ATOM   21713 C CA  . LEU G 1 356 ? 29.316  -12.548 61.292  1.00 25.27  ? 356 LEU G CA  1 
ATOM   21714 C C   . LEU G 1 356 ? 30.337  -13.139 60.338  1.00 26.75  ? 356 LEU G C   1 
ATOM   21715 O O   . LEU G 1 356 ? 30.434  -14.362 60.227  1.00 27.91  ? 356 LEU G O   1 
ATOM   21716 C CB  . LEU G 1 356 ? 28.021  -12.290 60.522  1.00 26.26  ? 356 LEU G CB  1 
ATOM   21717 C CG  . LEU G 1 356 ? 26.877  -11.826 61.406  1.00 26.39  ? 356 LEU G CG  1 
ATOM   21718 C CD1 . LEU G 1 356 ? 25.573  -11.992 60.647  1.00 25.52  ? 356 LEU G CD1 1 
ATOM   21719 C CD2 . LEU G 1 356 ? 26.911  -12.637 62.714  1.00 25.78  ? 356 LEU G CD2 1 
ATOM   21720 N N   . LEU G 1 357 ? 31.082  -12.301 59.614  1.00 26.65  ? 357 LEU G N   1 
ATOM   21721 C CA  . LEU G 1 357 ? 31.943  -12.797 58.554  1.00 25.88  ? 357 LEU G CA  1 
ATOM   21722 C C   . LEU G 1 357 ? 33.422  -12.472 58.715  1.00 22.99  ? 357 LEU G C   1 
ATOM   21723 O O   . LEU G 1 357 ? 34.209  -12.974 57.923  1.00 27.53  ? 357 LEU G O   1 
ATOM   21724 C CB  . LEU G 1 357 ? 31.476  -12.265 57.184  1.00 25.41  ? 357 LEU G CB  1 
ATOM   21725 C CG  . LEU G 1 357 ? 29.974  -12.262 56.918  1.00 25.01  ? 357 LEU G CG  1 
ATOM   21726 C CD1 . LEU G 1 357 ? 29.614  -11.186 55.923  1.00 24.97  ? 357 LEU G CD1 1 
ATOM   21727 C CD2 . LEU G 1 357 ? 29.496  -13.608 56.420  1.00 25.49  ? 357 LEU G CD2 1 
ATOM   21728 N N   . GLY G 1 358 ? 33.827  -11.634 59.664  1.00 26.25  ? 358 GLY G N   1 
ATOM   21729 C CA  . GLY G 1 358 ? 35.243  -11.419 59.898  1.00 24.90  ? 358 GLY G CA  1 
ATOM   21730 C C   . GLY G 1 358 ? 35.721  -10.054 59.404  1.00 30.10  ? 358 GLY G C   1 
ATOM   21731 O O   . GLY G 1 358 ? 35.115  -9.419  58.530  1.00 26.96  ? 358 GLY G O   1 
ATOM   21732 N N   . HIS G 1 359 ? 36.887  -9.640  59.938  1.00 27.45  ? 359 HIS G N   1 
ATOM   21733 C CA  . HIS G 1 359 ? 37.324  -8.237  59.906  1.00 31.44  ? 359 HIS G CA  1 
ATOM   21734 C C   . HIS G 1 359 ? 37.583  -7.712  58.490  1.00 34.51  ? 359 HIS G C   1 
ATOM   21735 O O   . HIS G 1 359 ? 37.386  -6.512  58.238  1.00 40.51  ? 359 HIS G O   1 
ATOM   21736 C CB  . HIS G 1 359 ? 38.572  -8.060  60.801  1.00 38.14  ? 359 HIS G CB  1 
ATOM   21737 C CG  . HIS G 1 359 ? 39.331  -6.774  60.584  1.00 48.93  ? 359 HIS G CG  1 
ATOM   21738 N ND1 . HIS G 1 359 ? 40.211  -6.582  59.534  1.00 50.51  ? 359 HIS G ND1 1 
ATOM   21739 C CD2 . HIS G 1 359 ? 39.382  -5.633  61.318  1.00 47.83  ? 359 HIS G CD2 1 
ATOM   21740 C CE1 . HIS G 1 359 ? 40.740  -5.372  59.607  1.00 35.81  ? 359 HIS G CE1 1 
ATOM   21741 N NE2 . HIS G 1 359 ? 40.260  -4.778  60.685  1.00 48.19  ? 359 HIS G NE2 1 
ATOM   21742 N N   . ASP G 1 360 ? 38.004  -8.554  57.546  1.00 27.34  ? 360 ASP G N   1 
ATOM   21743 C CA  . ASP G 1 360 ? 38.223  -8.081  56.179  1.00 25.44  ? 360 ASP G CA  1 
ATOM   21744 C C   . ASP G 1 360 ? 37.132  -8.566  55.224  1.00 27.51  ? 360 ASP G C   1 
ATOM   21745 O O   . ASP G 1 360 ? 37.391  -8.863  54.049  1.00 22.16  ? 360 ASP G O   1 
ATOM   21746 C CB  . ASP G 1 360 ? 39.606  -8.492  55.672  1.00 31.66  ? 360 ASP G CB  1 
ATOM   21747 C CG  . ASP G 1 360 ? 40.732  -7.774  56.400  1.00 30.96  ? 360 ASP G CG  1 
ATOM   21748 O OD1 . ASP G 1 360 ? 40.883  -6.554  56.215  1.00 29.39  ? 360 ASP G OD1 1 
ATOM   21749 O OD2 . ASP G 1 360 ? 41.464  -8.428  57.167  1.00 31.41  ? 360 ASP G OD2 1 
ATOM   21750 N N   . TYR G 1 361 ? 35.887  -8.623  55.719  1.00 25.33  ? 361 TYR G N   1 
ATOM   21751 C CA  . TYR G 1 361 ? 34.803  -9.202  54.933  1.00 21.47  ? 361 TYR G CA  1 
ATOM   21752 C C   . TYR G 1 361 ? 34.649  -8.510  53.587  1.00 23.72  ? 361 TYR G C   1 
ATOM   21753 O O   . TYR G 1 361 ? 34.254  -9.151  52.611  1.00 27.57  ? 361 TYR G O   1 
ATOM   21754 C CB  . TYR G 1 361 ? 33.487  -9.115  55.705  1.00 23.35  ? 361 TYR G CB  1 
ATOM   21755 C CG  . TYR G 1 361 ? 33.061  -7.691  55.904  1.00 21.66  ? 361 TYR G CG  1 
ATOM   21756 C CD1 . TYR G 1 361 ? 33.515  -6.956  56.999  1.00 24.15  ? 361 TYR G CD1 1 
ATOM   21757 C CD2 . TYR G 1 361 ? 32.252  -7.054  54.976  1.00 17.14  ? 361 TYR G CD2 1 
ATOM   21758 C CE1 . TYR G 1 361 ? 33.156  -5.638  57.165  1.00 19.97  ? 361 TYR G CE1 1 
ATOM   21759 C CE2 . TYR G 1 361 ? 31.893  -5.740  55.138  1.00 20.35  ? 361 TYR G CE2 1 
ATOM   21760 C CZ  . TYR G 1 361 ? 32.350  -5.036  56.226  1.00 20.07  ? 361 TYR G CZ  1 
ATOM   21761 O OH  . TYR G 1 361 ? 31.977  -3.726  56.387  1.00 26.46  ? 361 TYR G OH  1 
ATOM   21762 N N   . ALA G 1 362 ? 34.957  -7.207  53.507  1.00 20.67  ? 362 ALA G N   1 
ATOM   21763 C CA  . ALA G 1 362 ? 34.590  -6.465  52.310  1.00 25.84  ? 362 ALA G CA  1 
ATOM   21764 C C   . ALA G 1 362 ? 35.428  -6.846  51.109  1.00 24.55  ? 362 ALA G C   1 
ATOM   21765 O O   . ALA G 1 362 ? 35.120  -6.402  50.000  1.00 28.30  ? 362 ALA G O   1 
ATOM   21766 C CB  . ALA G 1 362 ? 34.686  -4.957  52.538  1.00 30.07  ? 362 ALA G CB  1 
ATOM   21767 N N   . ARG G 1 363 ? 36.448  -7.676  51.292  1.00 28.51  ? 363 ARG G N   1 
ATOM   21768 C CA  . ARG G 1 363 ? 37.244  -8.136  50.164  1.00 30.71  ? 363 ARG G CA  1 
ATOM   21769 C C   . ARG G 1 363 ? 36.634  -9.346  49.456  1.00 30.83  ? 363 ARG G C   1 
ATOM   21770 O O   . ARG G 1 363 ? 36.959  -9.603  48.289  1.00 23.32  ? 363 ARG G O   1 
ATOM   21771 C CB  . ARG G 1 363 ? 38.654  -8.465  50.640  1.00 30.78  ? 363 ARG G CB  1 
ATOM   21772 C CG  . ARG G 1 363 ? 39.528  -7.235  50.770  1.00 35.34  ? 363 ARG G CG  1 
ATOM   21773 C CD  . ARG G 1 363 ? 40.647  -7.437  51.794  1.00 37.59  ? 363 ARG G CD  1 
ATOM   21774 N NE  . ARG G 1 363 ? 41.460  -6.232  51.937  1.00 39.02  ? 363 ARG G NE  1 
ATOM   21775 C CZ  . ARG G 1 363 ? 42.620  -6.182  52.577  1.00 39.55  ? 363 ARG G CZ  1 
ATOM   21776 N NH1 . ARG G 1 363 ? 43.132  -7.256  53.165  1.00 30.63  ? 363 ARG G NH1 1 
ATOM   21777 N NH2 . ARG G 1 363 ? 43.294  -5.032  52.607  1.00 33.94  ? 363 ARG G NH2 1 
ATOM   21778 N N   . ASN G 1 364 ? 35.748  -10.083 50.119  1.00 26.56  ? 364 ASN G N   1 
ATOM   21779 C CA  . ASN G 1 364 ? 35.214  -11.294 49.511  1.00 29.21  ? 364 ASN G CA  1 
ATOM   21780 C C   . ASN G 1 364 ? 33.710  -11.404 49.714  1.00 33.90  ? 364 ASN G C   1 
ATOM   21781 O O   . ASN G 1 364 ? 33.132  -12.473 49.451  1.00 26.05  ? 364 ASN G O   1 
ATOM   21782 C CB  . ASN G 1 364 ? 35.917  -12.523 50.096  1.00 29.92  ? 364 ASN G CB  1 
ATOM   21783 C CG  . ASN G 1 364 ? 37.357  -12.617 49.668  1.00 30.09  ? 364 ASN G CG  1 
ATOM   21784 O OD1 . ASN G 1 364 ? 37.647  -12.703 48.480  1.00 39.71  ? 364 ASN G OD1 1 
ATOM   21785 N ND2 . ASN G 1 364 ? 38.274  -12.575 50.630  1.00 25.37  ? 364 ASN G ND2 1 
ATOM   21786 N N   . ASN G 1 365 ? 33.066  -10.353 50.205  1.00 26.14  ? 365 ASN G N   1 
ATOM   21787 C CA  . ASN G 1 365 ? 31.650  -10.420 50.491  1.00 31.89  ? 365 ASN G CA  1 
ATOM   21788 C C   . ASN G 1 365 ? 30.992  -9.123  50.099  1.00 29.40  ? 365 ASN G C   1 
ATOM   21789 O O   . ASN G 1 365 ? 31.647  -8.103  49.865  1.00 28.77  ? 365 ASN G O   1 
ATOM   21790 C CB  . ASN G 1 365 ? 31.389  -10.690 51.960  1.00 28.18  ? 365 ASN G CB  1 
ATOM   21791 C CG  . ASN G 1 365 ? 31.952  -11.987 52.380  1.00 31.68  ? 365 ASN G CG  1 
ATOM   21792 O OD1 . ASN G 1 365 ? 31.382  -13.031 52.063  1.00 27.49  ? 365 ASN G OD1 1 
ATOM   21793 N ND2 . ASN G 1 365 ? 33.104  -11.953 53.068  1.00 23.85  ? 365 ASN G ND2 1 
ATOM   21794 N N   . PHE G 1 366 ? 29.677  -9.186  50.059  1.00 25.72  ? 366 PHE G N   1 
ATOM   21795 C CA  . PHE G 1 366 ? 28.844  -8.027  49.828  1.00 28.94  ? 366 PHE G CA  1 
ATOM   21796 C C   . PHE G 1 366 ? 27.754  -8.025  50.883  1.00 24.06  ? 366 PHE G C   1 
ATOM   21797 O O   . PHE G 1 366 ? 27.342  -9.086  51.370  1.00 21.97  ? 366 PHE G O   1 
ATOM   21798 C CB  . PHE G 1 366 ? 28.224  -8.052  48.425  1.00 26.86  ? 366 PHE G CB  1 
ATOM   21799 C CG  . PHE G 1 366 ? 29.228  -8.185  47.305  1.00 27.70  ? 366 PHE G CG  1 
ATOM   21800 C CD1 . PHE G 1 366 ? 29.597  -9.435  46.833  1.00 31.57  ? 366 PHE G CD1 1 
ATOM   21801 C CD2 . PHE G 1 366 ? 29.761  -7.060  46.685  1.00 33.49  ? 366 PHE G CD2 1 
ATOM   21802 C CE1 . PHE G 1 366 ? 30.509  -9.570  45.779  1.00 31.70  ? 366 PHE G CE1 1 
ATOM   21803 C CE2 . PHE G 1 366 ? 30.673  -7.187  45.625  1.00 31.92  ? 366 PHE G CE2 1 
ATOM   21804 C CZ  . PHE G 1 366 ? 31.045  -8.454  45.178  1.00 26.15  ? 366 PHE G CZ  1 
ATOM   21805 N N   . PHE G 1 367 ? 27.286  -6.833  51.239  1.00 23.76  ? 367 PHE G N   1 
ATOM   21806 C CA  . PHE G 1 367 ? 26.054  -6.743  51.997  1.00 27.83  ? 367 PHE G CA  1 
ATOM   21807 C C   . PHE G 1 367 ? 25.185  -5.623  51.453  1.00 29.11  ? 367 PHE G C   1 
ATOM   21808 O O   . PHE G 1 367 ? 25.640  -4.725  50.740  1.00 26.40  ? 367 PHE G O   1 
ATOM   21809 C CB  . PHE G 1 367 ? 26.295  -6.611  53.525  1.00 26.88  ? 367 PHE G CB  1 
ATOM   21810 C CG  . PHE G 1 367 ? 26.853  -5.275  54.007  1.00 25.39  ? 367 PHE G CG  1 
ATOM   21811 C CD1 . PHE G 1 367 ? 26.090  -4.125  54.008  1.00 24.41  ? 367 PHE G CD1 1 
ATOM   21812 C CD2 . PHE G 1 367 ? 28.109  -5.218  54.587  1.00 22.26  ? 367 PHE G CD2 1 
ATOM   21813 C CE1 . PHE G 1 367 ? 26.594  -2.934  54.519  1.00 26.17  ? 367 PHE G CE1 1 
ATOM   21814 C CE2 . PHE G 1 367 ? 28.613  -4.026  55.109  1.00 22.77  ? 367 PHE G CE2 1 
ATOM   21815 C CZ  . PHE G 1 367 ? 27.849  -2.887  55.077  1.00 21.51  ? 367 PHE G CZ  1 
ATOM   21816 N N   . SER G 1 368 ? 23.903  -5.714  51.801  1.00 26.52  ? 368 SER G N   1 
ATOM   21817 C CA  . SER G 1 368 ? 22.897  -4.814  51.278  1.00 28.13  ? 368 SER G CA  1 
ATOM   21818 C C   . SER G 1 368 ? 21.702  -4.839  52.209  1.00 27.37  ? 368 SER G C   1 
ATOM   21819 O O   . SER G 1 368 ? 21.155  -5.911  52.495  1.00 24.09  ? 368 SER G O   1 
ATOM   21820 C CB  . SER G 1 368 ? 22.477  -5.211  49.870  1.00 31.15  ? 368 SER G CB  1 
ATOM   21821 O OG  . SER G 1 368 ? 21.531  -4.288  49.376  1.00 34.46  ? 368 SER G OG  1 
ATOM   21822 N N   . SER G 1 369 ? 21.301  -3.670  52.673  1.00 23.76  ? 369 SER G N   1 
ATOM   21823 C CA  . SER G 1 369 ? 20.154  -3.577  53.556  1.00 30.10  ? 369 SER G CA  1 
ATOM   21824 C C   . SER G 1 369 ? 18.925  -3.171  52.755  1.00 27.04  ? 369 SER G C   1 
ATOM   21825 O O   . SER G 1 369 ? 19.032  -2.610  51.666  1.00 26.70  ? 369 SER G O   1 
ATOM   21826 C CB  . SER G 1 369 ? 20.413  -2.582  54.685  1.00 26.85  ? 369 SER G CB  1 
ATOM   21827 O OG  . SER G 1 369 ? 20.454  -1.262  54.187  1.00 27.44  ? 369 SER G OG  1 
ATOM   21828 N N   . ILE G 1 370 ? 17.755  -3.511  53.293  1.00 28.09  ? 370 ILE G N   1 
ATOM   21829 C CA  . ILE G 1 370 ? 16.453  -3.130  52.742  1.00 27.50  ? 370 ILE G CA  1 
ATOM   21830 C C   . ILE G 1 370 ? 15.698  -2.466  53.882  1.00 29.69  ? 370 ILE G C   1 
ATOM   21831 O O   . ILE G 1 370 ? 15.544  -3.063  54.956  1.00 26.20  ? 370 ILE G O   1 
ATOM   21832 C CB  . ILE G 1 370 ? 15.673  -4.344  52.195  1.00 31.50  ? 370 ILE G CB  1 
ATOM   21833 C CG1 . ILE G 1 370 ? 16.570  -5.225  51.325  1.00 23.05  ? 370 ILE G CG1 1 
ATOM   21834 C CG2 . ILE G 1 370 ? 14.435  -3.917  51.379  1.00 24.02  ? 370 ILE G CG2 1 
ATOM   21835 C CD1 . ILE G 1 370 ? 16.125  -6.708  51.259  1.00 22.68  ? 370 ILE G CD1 1 
ATOM   21836 N N   . LEU G 1 371 ? 15.310  -1.213  53.693  1.00 28.59  ? 371 LEU G N   1 
ATOM   21837 C CA  . LEU G 1 371 ? 14.622  -0.486  54.754  1.00 32.55  ? 371 LEU G CA  1 
ATOM   21838 C C   . LEU G 1 371 ? 13.123  -0.549  54.585  1.00 27.10  ? 371 LEU G C   1 
ATOM   21839 O O   . LEU G 1 371 ? 12.392  -0.031  55.431  1.00 27.90  ? 371 LEU G O   1 
ATOM   21840 C CB  . LEU G 1 371 ? 15.076  0.978   54.796  1.00 28.52  ? 371 LEU G CB  1 
ATOM   21841 C CG  . LEU G 1 371 ? 16.579  1.237   54.810  1.00 37.40  ? 371 LEU G CG  1 
ATOM   21842 C CD1 . LEU G 1 371 ? 16.849  2.686   54.428  1.00 39.11  ? 371 LEU G CD1 1 
ATOM   21843 C CD2 . LEU G 1 371 ? 17.175  0.911   56.184  1.00 29.52  ? 371 LEU G CD2 1 
ATOM   21844 N N   . ASN G 1 372 ? 12.689  -1.326  53.605  1.00 32.19  ? 372 ASN G N   1 
ATOM   21845 C CA  . ASN G 1 372 ? 11.484  -1.161  52.821  1.00 32.80  ? 372 ASN G CA  1 
ATOM   21846 C C   . ASN G 1 372 ? 10.481  -2.287  52.993  1.00 30.78  ? 372 ASN G C   1 
ATOM   21847 O O   . ASN G 1 372 ? 9.441   -2.267  52.318  1.00 31.44  ? 372 ASN G O   1 
ATOM   21848 C CB  . ASN G 1 372 ? 11.886  -1.112  51.337  1.00 37.57  ? 372 ASN G CB  1 
ATOM   21849 C CG  . ASN G 1 372 ? 11.259  0.026   50.617  1.00 43.45  ? 372 ASN G CG  1 
ATOM   21850 O OD1 . ASN G 1 372 ? 10.456  0.751   51.196  1.00 52.72  ? 372 ASN G OD1 1 
ATOM   21851 N ND2 . ASN G 1 372 ? 11.602  0.196   49.343  1.00 42.06  ? 372 ASN G ND2 1 
ATOM   21852 N N   . VAL G 1 373 ? 10.791  -3.295  53.818  1.00 26.49  ? 373 VAL G N   1 
ATOM   21853 C CA  . VAL G 1 373 ? 10.006  -4.529  53.865  1.00 25.44  ? 373 VAL G CA  1 
ATOM   21854 C C   . VAL G 1 373 ? 8.693   -4.270  54.595  1.00 27.95  ? 373 VAL G C   1 
ATOM   21855 O O   . VAL G 1 373 ? 8.611   -3.388  55.459  1.00 28.74  ? 373 VAL G O   1 
ATOM   21856 C CB  . VAL G 1 373 ? 10.831  -5.643  54.551  1.00 28.75  ? 373 VAL G CB  1 
ATOM   21857 C CG1 . VAL G 1 373 ? 10.034  -6.897  54.746  1.00 23.90  ? 373 VAL G CG1 1 
ATOM   21858 C CG2 . VAL G 1 373 ? 12.058  -5.953  53.745  1.00 25.17  ? 373 VAL G CG2 1 
ATOM   21859 N N   . VAL G 1 374 ? 7.648   -5.020  54.233  1.00 29.92  ? 374 VAL G N   1 
ATOM   21860 C CA  . VAL G 1 374 ? 6.383   -4.888  54.970  1.00 27.67  ? 374 VAL G CA  1 
ATOM   21861 C C   . VAL G 1 374 ? 6.639   -5.224  56.431  1.00 26.95  ? 374 VAL G C   1 
ATOM   21862 O O   . VAL G 1 374 ? 7.226   -6.288  56.730  1.00 25.87  ? 374 VAL G O   1 
ATOM   21863 C CB  . VAL G 1 374 ? 5.289   -5.801  54.383  1.00 27.66  ? 374 VAL G CB  1 
ATOM   21864 C CG1 . VAL G 1 374 ? 4.067   -5.834  55.313  1.00 26.27  ? 374 VAL G CG1 1 
ATOM   21865 C CG2 . VAL G 1 374 ? 4.877   -5.340  53.014  1.00 29.43  ? 374 VAL G CG2 1 
ATOM   21866 N N   . PRO G 1 375 ? 6.270   -4.352  57.367  1.00 24.96  ? 375 PRO G N   1 
ATOM   21867 C CA  . PRO G 1 375 ? 6.548   -4.631  58.782  1.00 29.49  ? 375 PRO G CA  1 
ATOM   21868 C C   . PRO G 1 375 ? 5.685   -5.765  59.297  1.00 28.21  ? 375 PRO G C   1 
ATOM   21869 O O   . PRO G 1 375 ? 4.520   -5.913  58.919  1.00 24.88  ? 375 PRO G O   1 
ATOM   21870 C CB  . PRO G 1 375 ? 6.227   -3.310  59.499  1.00 26.29  ? 375 PRO G CB  1 
ATOM   21871 C CG  . PRO G 1 375 ? 5.761   -2.367  58.495  1.00 25.58  ? 375 PRO G CG  1 
ATOM   21872 C CD  . PRO G 1 375 ? 5.670   -3.026  57.147  1.00 26.23  ? 375 PRO G CD  1 
ATOM   21873 N N   . ALA G 1 376 ? 6.284   -6.579  60.160  1.00 23.05  ? 376 ALA G N   1 
ATOM   21874 C CA  . ALA G 1 376 ? 5.610   -7.746  60.704  1.00 30.47  ? 376 ALA G CA  1 
ATOM   21875 C C   . ALA G 1 376 ? 6.367   -8.147  61.951  1.00 28.51  ? 376 ALA G C   1 
ATOM   21876 O O   . ALA G 1 376 ? 7.528   -7.776  62.122  1.00 27.75  ? 376 ALA G O   1 
ATOM   21877 C CB  . ALA G 1 376 ? 5.561   -8.909  59.700  1.00 24.18  ? 376 ALA G CB  1 
ATOM   21878 N N   . GLY G 1 377 ? 5.686   -8.878  62.836  1.00 31.51  ? 377 GLY G N   1 
ATOM   21879 C CA  . GLY G 1 377 ? 6.336   -9.387  64.028  1.00 27.65  ? 377 GLY G CA  1 
ATOM   21880 C C   . GLY G 1 377 ? 7.543   -10.237 63.690  1.00 29.29  ? 377 GLY G C   1 
ATOM   21881 O O   . GLY G 1 377 ? 7.679   -10.768 62.580  1.00 24.77  ? 377 GLY G O   1 
ATOM   21882 N N   . LEU G 1 378 ? 8.457   -10.336 64.661  1.00 30.49  ? 378 LEU G N   1 
ATOM   21883 C CA  . LEU G 1 378 ? 9.720   -11.035 64.408  1.00 31.36  ? 378 LEU G CA  1 
ATOM   21884 C C   . LEU G 1 378 ? 9.481   -12.459 63.912  1.00 24.08  ? 378 LEU G C   1 
ATOM   21885 O O   . LEU G 1 378 ? 10.150  -12.923 62.983  1.00 25.87  ? 378 LEU G O   1 
ATOM   21886 C CB  . LEU G 1 378 ? 10.583  -11.044 65.669  1.00 25.23  ? 378 LEU G CB  1 
ATOM   21887 C CG  . LEU G 1 378 ? 11.989  -11.625 65.483  1.00 29.89  ? 378 LEU G CG  1 
ATOM   21888 C CD1 . LEU G 1 378 ? 12.858  -10.790 64.546  1.00 26.26  ? 378 LEU G CD1 1 
ATOM   21889 C CD2 . LEU G 1 378 ? 12.661  -11.783 66.833  1.00 29.70  ? 378 LEU G CD2 1 
ATOM   21890 N N   . ALA G 1 379 ? 8.518   -13.158 64.505  1.00 27.51  ? 379 ALA G N   1 
ATOM   21891 C CA  . ALA G 1 379 ? 8.284   -14.546 64.124  1.00 31.53  ? 379 ALA G CA  1 
ATOM   21892 C C   . ALA G 1 379 ? 7.880   -14.648 62.669  1.00 24.41  ? 379 ALA G C   1 
ATOM   21893 O O   . ALA G 1 379 ? 8.285   -15.580 61.968  1.00 24.19  ? 379 ALA G O   1 
ATOM   21894 C CB  . ALA G 1 379 ? 7.208   -15.169 65.007  1.00 29.67  ? 379 ALA G CB  1 
ATOM   21895 N N   . ASP G 1 380 ? 7.107   -13.682 62.189  1.00 26.15  ? 380 ASP G N   1 
ATOM   21896 C CA  . ASP G 1 380 ? 6.639   -13.751 60.813  1.00 27.63  ? 380 ASP G CA  1 
ATOM   21897 C C   . ASP G 1 380 ? 7.719   -13.314 59.837  1.00 30.41  ? 380 ASP G C   1 
ATOM   21898 O O   . ASP G 1 380 ? 7.851   -13.905 58.759  1.00 25.46  ? 380 ASP G O   1 
ATOM   21899 C CB  . ASP G 1 380 ? 5.380   -12.912 60.644  1.00 33.73  ? 380 ASP G CB  1 
ATOM   21900 C CG  . ASP G 1 380 ? 4.138   -13.625 61.163  1.00 39.69  ? 380 ASP G CG  1 
ATOM   21901 O OD1 . ASP G 1 380 ? 4.029   -14.858 60.969  1.00 38.02  ? 380 ASP G OD1 1 
ATOM   21902 O OD2 . ASP G 1 380 ? 3.260   -12.953 61.746  1.00 40.51  ? 380 ASP G OD2 1 
ATOM   21903 N N   . LEU G 1 381 ? 8.510   -12.297 60.204  1.00 33.33  ? 381 LEU G N   1 
ATOM   21904 C CA  . LEU G 1 381 ? 9.656   -11.912 59.387  1.00 28.15  ? 381 LEU G CA  1 
ATOM   21905 C C   . LEU G 1 381 ? 10.627  -13.075 59.229  1.00 24.82  ? 381 LEU G C   1 
ATOM   21906 O O   . LEU G 1 381 ? 11.017  -13.428 58.109  1.00 20.73  ? 381 LEU G O   1 
ATOM   21907 C CB  . LEU G 1 381 ? 10.359  -10.706 60.013  1.00 28.60  ? 381 LEU G CB  1 
ATOM   21908 C CG  . LEU G 1 381 ? 9.661   -9.350  59.824  1.00 30.49  ? 381 LEU G CG  1 
ATOM   21909 C CD1 . LEU G 1 381 ? 10.416  -8.263  60.592  1.00 26.45  ? 381 LEU G CD1 1 
ATOM   21910 C CD2 . LEU G 1 381 ? 9.547   -9.017  58.349  1.00 27.01  ? 381 LEU G CD2 1 
ATOM   21911 N N   . LEU G 1 382 ? 11.017  -13.695 60.350  1.00 26.34  ? 382 LEU G N   1 
ATOM   21912 C CA  . LEU G 1 382 ? 11.950  -14.823 60.289  1.00 27.97  ? 382 LEU G CA  1 
ATOM   21913 C C   . LEU G 1 382 ? 11.378  -15.955 59.450  1.00 24.94  ? 382 LEU G C   1 
ATOM   21914 O O   . LEU G 1 382 ? 12.109  -16.636 58.728  1.00 24.46  ? 382 LEU G O   1 
ATOM   21915 C CB  . LEU G 1 382 ? 12.289  -15.321 61.704  1.00 25.19  ? 382 LEU G CB  1 
ATOM   21916 C CG  . LEU G 1 382 ? 13.330  -14.469 62.434  1.00 26.15  ? 382 LEU G CG  1 
ATOM   21917 C CD1 . LEU G 1 382 ? 13.458  -14.786 63.928  1.00 22.80  ? 382 LEU G CD1 1 
ATOM   21918 C CD2 . LEU G 1 382 ? 14.664  -14.635 61.732  1.00 30.16  ? 382 LEU G CD2 1 
ATOM   21919 N N   . ARG G 1 383 ? 10.064  -16.155 59.514  1.00 25.89  ? 383 ARG G N   1 
ATOM   21920 C CA  . ARG G 1 383 ? 9.450   -17.227 58.736  1.00 29.32  ? 383 ARG G CA  1 
ATOM   21921 C C   . ARG G 1 383 ? 9.486   -16.915 57.244  1.00 30.64  ? 383 ARG G C   1 
ATOM   21922 O O   . ARG G 1 383 ? 9.754   -17.807 56.426  1.00 26.50  ? 383 ARG G O   1 
ATOM   21923 C CB  . ARG G 1 383 ? 8.020   -17.454 59.213  1.00 25.42  ? 383 ARG G CB  1 
ATOM   21924 C CG  . ARG G 1 383 ? 7.214   -18.381 58.356  1.00 26.32  ? 383 ARG G CG  1 
ATOM   21925 C CD  . ARG G 1 383 ? 7.179   -19.767 58.957  1.00 19.91  ? 383 ARG G CD  1 
ATOM   21926 N NE  . ARG G 1 383 ? 8.469   -20.443 58.890  1.00 24.89  ? 383 ARG G NE  1 
ATOM   21927 C CZ  . ARG G 1 383 ? 8.890   -21.128 57.835  1.00 29.85  ? 383 ARG G CZ  1 
ATOM   21928 N NH1 . ARG G 1 383 ? 8.172   -21.195 56.723  1.00 28.86  ? 383 ARG G NH1 1 
ATOM   21929 N NH2 . ARG G 1 383 ? 10.066  -21.749 57.889  1.00 31.01  ? 383 ARG G NH2 1 
ATOM   21930 N N   . SER G 1 384 ? 9.232   -15.649 56.874  1.00 26.00  ? 384 SER G N   1 
ATOM   21931 C CA  . SER G 1 384 ? 9.328   -15.254 55.476  1.00 25.62  ? 384 SER G CA  1 
ATOM   21932 C C   . SER G 1 384 ? 10.741  -15.456 54.947  1.00 29.51  ? 384 SER G C   1 
ATOM   21933 O O   . SER G 1 384 ? 10.931  -15.889 53.805  1.00 28.22  ? 384 SER G O   1 
ATOM   21934 C CB  . SER G 1 384 ? 8.913   -13.794 55.321  1.00 30.20  ? 384 SER G CB  1 
ATOM   21935 O OG  . SER G 1 384 ? 7.550   -13.622 55.659  1.00 36.64  ? 384 SER G OG  1 
ATOM   21936 N N   . LEU G 1 385 ? 11.754  -15.154 55.763  1.00 24.51  ? 385 LEU G N   1 
ATOM   21937 C CA  . LEU G 1 385 ? 13.114  -15.412 55.317  1.00 26.69  ? 385 LEU G CA  1 
ATOM   21938 C C   . LEU G 1 385 ? 13.317  -16.899 55.035  1.00 25.17  ? 385 LEU G C   1 
ATOM   21939 O O   . LEU G 1 385 ? 13.857  -17.270 53.988  1.00 26.77  ? 385 LEU G O   1 
ATOM   21940 C CB  . LEU G 1 385 ? 14.112  -14.892 56.347  1.00 27.02  ? 385 LEU G CB  1 
ATOM   21941 C CG  . LEU G 1 385 ? 14.179  -13.383 56.546  1.00 25.15  ? 385 LEU G CG  1 
ATOM   21942 C CD1 . LEU G 1 385 ? 15.289  -13.051 57.534  1.00 24.79  ? 385 LEU G CD1 1 
ATOM   21943 C CD2 . LEU G 1 385 ? 14.417  -12.705 55.211  1.00 24.17  ? 385 LEU G CD2 1 
ATOM   21944 N N   . GLU G 1 386 ? 12.860  -17.771 55.941  1.00 24.93  ? 386 GLU G N   1 
ATOM   21945 C CA  . GLU G 1 386 ? 13.039  -19.212 55.731  1.00 23.93  ? 386 GLU G CA  1 
ATOM   21946 C C   . GLU G 1 386 ? 12.286  -19.697 54.502  1.00 26.41  ? 386 GLU G C   1 
ATOM   21947 O O   . GLU G 1 386 ? 12.783  -20.545 53.753  1.00 27.42  ? 386 GLU G O   1 
ATOM   21948 C CB  . GLU G 1 386 ? 12.577  -19.983 56.956  1.00 28.54  ? 386 GLU G CB  1 
ATOM   21949 C CG  . GLU G 1 386 ? 13.671  -20.277 57.918  1.00 29.95  ? 386 GLU G CG  1 
ATOM   21950 C CD  . GLU G 1 386 ? 13.165  -20.728 59.261  1.00 30.55  ? 386 GLU G CD  1 
ATOM   21951 O OE1 . GLU G 1 386 ? 12.716  -21.891 59.385  1.00 31.22  ? 386 GLU G OE1 1 
ATOM   21952 O OE2 . GLU G 1 386 ? 13.202  -19.897 60.191  1.00 29.61  ? 386 GLU G OE2 1 
ATOM   21953 N N   . ARG G 1 387 ? 11.087  -19.155 54.268  1.00 28.95  ? 387 ARG G N   1 
ATOM   21954 C CA  . ARG G 1 387 ? 10.301  -19.561 53.108  1.00 28.70  ? 387 ARG G CA  1 
ATOM   21955 C C   . ARG G 1 387 ? 10.996  -19.203 51.794  1.00 33.03  ? 387 ARG G C   1 
ATOM   21956 O O   . ARG G 1 387 ? 10.824  -19.893 50.777  1.00 31.72  ? 387 ARG G O   1 
ATOM   21957 C CB  . ARG G 1 387 ? 8.917   -18.915 53.187  1.00 25.12  ? 387 ARG G CB  1 
ATOM   21958 C CG  . ARG G 1 387 ? 8.140   -19.030 51.898  1.00 31.07  ? 387 ARG G CG  1 
ATOM   21959 C CD  . ARG G 1 387 ? 6.841   -18.277 51.965  1.00 36.50  ? 387 ARG G CD  1 
ATOM   21960 N NE  . ARG G 1 387 ? 6.359   -18.235 53.334  1.00 37.37  ? 387 ARG G NE  1 
ATOM   21961 C CZ  . ARG G 1 387 ? 6.162   -17.122 54.024  1.00 31.16  ? 387 ARG G CZ  1 
ATOM   21962 N NH1 . ARG G 1 387 ? 6.313   -15.934 53.470  1.00 30.36  ? 387 ARG G NH1 1 
ATOM   21963 N NH2 . ARG G 1 387 ? 5.808   -17.208 55.302  1.00 24.94  ? 387 ARG G NH2 1 
ATOM   21964 N N   . ALA G 1 388 ? 11.780  -18.132 51.787  1.00 35.27  ? 388 ALA G N   1 
ATOM   21965 C CA  . ALA G 1 388 ? 12.540  -17.756 50.603  1.00 36.14  ? 388 ALA G CA  1 
ATOM   21966 C C   . ALA G 1 388 ? 13.891  -18.458 50.511  1.00 31.03  ? 388 ALA G C   1 
ATOM   21967 O O   . ALA G 1 388 ? 14.551  -18.371 49.472  1.00 34.42  ? 388 ALA G O   1 
ATOM   21968 C CB  . ALA G 1 388 ? 12.742  -16.235 50.574  1.00 34.97  ? 388 ALA G CB  1 
ATOM   21969 N N   . GLY G 1 389 ? 14.309  -19.169 51.548  1.00 29.22  ? 389 GLY G N   1 
ATOM   21970 C CA  . GLY G 1 389 ? 15.610  -19.806 51.517  1.00 25.53  ? 389 GLY G CA  1 
ATOM   21971 C C   . GLY G 1 389 ? 16.771  -18.866 51.779  1.00 32.26  ? 389 GLY G C   1 
ATOM   21972 O O   . GLY G 1 389 ? 17.906  -19.158 51.376  1.00 28.23  ? 389 GLY G O   1 
ATOM   21973 N N   . VAL G 1 390 ? 16.534  -17.749 52.467  1.00 28.20  ? 390 VAL G N   1 
ATOM   21974 C CA  . VAL G 1 390 ? 17.601  -16.773 52.629  1.00 28.53  ? 390 VAL G CA  1 
ATOM   21975 C C   . VAL G 1 390 ? 17.814  -16.359 54.077  1.00 28.43  ? 390 VAL G C   1 
ATOM   21976 O O   . VAL G 1 390 ? 18.432  -15.321 54.327  1.00 25.81  ? 390 VAL G O   1 
ATOM   21977 C CB  . VAL G 1 390 ? 17.315  -15.533 51.778  1.00 29.34  ? 390 VAL G CB  1 
ATOM   21978 C CG1 . VAL G 1 390 ? 17.186  -15.903 50.308  1.00 31.17  ? 390 VAL G CG1 1 
ATOM   21979 C CG2 . VAL G 1 390 ? 16.053  -14.867 52.282  1.00 28.60  ? 390 VAL G CG2 1 
ATOM   21980 N N   . ARG G 1 391 ? 17.296  -17.118 55.042  1.00 25.50  ? 391 ARG G N   1 
ATOM   21981 C CA  . ARG G 1 391 ? 17.628  -16.795 56.427  1.00 28.90  ? 391 ARG G CA  1 
ATOM   21982 C C   . ARG G 1 391 ? 19.124  -16.958 56.623  1.00 27.95  ? 391 ARG G C   1 
ATOM   21983 O O   . ARG G 1 391 ? 19.704  -17.953 56.183  1.00 26.46  ? 391 ARG G O   1 
ATOM   21984 C CB  . ARG G 1 391 ? 16.888  -17.682 57.426  1.00 26.55  ? 391 ARG G CB  1 
ATOM   21985 C CG  . ARG G 1 391 ? 17.319  -17.425 58.876  1.00 25.64  ? 391 ARG G CG  1 
ATOM   21986 C CD  . ARG G 1 391 ? 16.279  -17.844 59.894  1.00 19.53  ? 391 ARG G CD  1 
ATOM   21987 N NE  . ARG G 1 391 ? 16.717  -17.588 61.260  1.00 20.96  ? 391 ARG G NE  1 
ATOM   21988 C CZ  . ARG G 1 391 ? 16.015  -17.901 62.346  1.00 24.39  ? 391 ARG G CZ  1 
ATOM   21989 N NH1 . ARG G 1 391 ? 14.835  -18.510 62.264  1.00 18.00  ? 391 ARG G NH1 1 
ATOM   21990 N NH2 . ARG G 1 391 ? 16.510  -17.603 63.544  1.00 20.09  ? 391 ARG G NH2 1 
ATOM   21991 N N   . TYR G 1 392 ? 19.750  -15.967 57.259  1.00 28.25  ? 392 TYR G N   1 
ATOM   21992 C CA  . TYR G 1 392 ? 21.195  -15.991 57.435  1.00 27.70  ? 392 TYR G CA  1 
ATOM   21993 C C   . TYR G 1 392 ? 21.664  -17.349 57.932  1.00 25.99  ? 392 TYR G C   1 
ATOM   21994 O O   . TYR G 1 392 ? 21.216  -17.822 58.982  1.00 29.09  ? 392 TYR G O   1 
ATOM   21995 C CB  . TYR G 1 392 ? 21.651  -14.915 58.412  1.00 21.09  ? 392 TYR G CB  1 
ATOM   21996 C CG  . TYR G 1 392 ? 23.151  -14.959 58.546  1.00 27.19  ? 392 TYR G CG  1 
ATOM   21997 C CD1 . TYR G 1 392 ? 23.961  -14.505 57.500  1.00 24.17  ? 392 TYR G CD1 1 
ATOM   21998 C CD2 . TYR G 1 392 ? 23.764  -15.529 59.672  1.00 20.16  ? 392 TYR G CD2 1 
ATOM   21999 C CE1 . TYR G 1 392 ? 25.337  -14.564 57.586  1.00 24.18  ? 392 TYR G CE1 1 
ATOM   22000 C CE2 . TYR G 1 392 ? 25.135  -15.593 59.771  1.00 22.79  ? 392 TYR G CE2 1 
ATOM   22001 C CZ  . TYR G 1 392 ? 25.916  -15.106 58.723  1.00 27.80  ? 392 TYR G CZ  1 
ATOM   22002 O OH  . TYR G 1 392 ? 27.275  -15.162 58.785  1.00 30.00  ? 392 TYR G OH  1 
ATOM   22003 N N   . ASP G 1 393 ? 22.583  -17.951 57.176  1.00 24.16  ? 393 ASP G N   1 
ATOM   22004 C CA  . ASP G 1 393 ? 23.156  -19.269 57.443  1.00 29.23  ? 393 ASP G CA  1 
ATOM   22005 C C   . ASP G 1 393 ? 24.604  -19.073 57.886  1.00 28.91  ? 393 ASP G C   1 
ATOM   22006 O O   . ASP G 1 393 ? 25.461  -18.706 57.076  1.00 28.99  ? 393 ASP G O   1 
ATOM   22007 C CB  . ASP G 1 393 ? 23.076  -20.141 56.184  1.00 28.45  ? 393 ASP G CB  1 
ATOM   22008 C CG  . ASP G 1 393 ? 23.777  -21.497 56.336  1.00 35.08  ? 393 ASP G CG  1 
ATOM   22009 O OD1 . ASP G 1 393 ? 24.333  -21.805 57.414  1.00 34.48  ? 393 ASP G OD1 1 
ATOM   22010 O OD2 . ASP G 1 393 ? 23.805  -22.256 55.341  1.00 45.51  ? 393 ASP G OD2 1 
ATOM   22011 N N   . LYS G 1 394 ? 24.883  -19.341 59.161  1.00 29.33  ? 394 LYS G N   1 
ATOM   22012 C CA  . LYS G 1 394 ? 26.233  -19.147 59.681  1.00 28.02  ? 394 LYS G CA  1 
ATOM   22013 C C   . LYS G 1 394 ? 27.241  -20.111 59.065  1.00 32.56  ? 394 LYS G C   1 
ATOM   22014 O O   . LYS G 1 394 ? 28.449  -19.905 59.215  1.00 39.16  ? 394 LYS G O   1 
ATOM   22015 C CB  . LYS G 1 394 ? 26.228  -19.289 61.203  1.00 29.12  ? 394 LYS G CB  1 
ATOM   22016 C CG  . LYS G 1 394 ? 25.942  -20.727 61.698  1.00 37.90  ? 394 LYS G CG  1 
ATOM   22017 C CD  . LYS G 1 394 ? 24.451  -20.982 61.894  1.00 41.25  ? 394 LYS G CD  1 
ATOM   22018 C CE  . LYS G 1 394 ? 24.198  -22.196 62.807  1.00 53.16  ? 394 LYS G CE  1 
ATOM   22019 N NZ  . LYS G 1 394 ? 22.794  -22.246 63.359  1.00 56.51  ? 394 LYS G NZ  1 
ATOM   22020 N N   . ASP G 1 395 ? 26.784  -21.164 58.387  1.00 32.36  ? 395 ASP G N   1 
ATOM   22021 C CA  . ASP G 1 395 ? 27.714  -22.083 57.738  1.00 31.96  ? 395 ASP G CA  1 
ATOM   22022 C C   . ASP G 1 395 ? 28.161  -21.597 56.363  1.00 34.20  ? 395 ASP G C   1 
ATOM   22023 O O   . ASP G 1 395 ? 29.272  -21.914 55.931  1.00 40.04  ? 395 ASP G O   1 
ATOM   22024 C CB  . ASP G 1 395 ? 27.085  -23.474 57.618  1.00 38.17  ? 395 ASP G CB  1 
ATOM   22025 C CG  . ASP G 1 395 ? 26.801  -24.108 58.975  1.00 40.42  ? 395 ASP G CG  1 
ATOM   22026 O OD1 . ASP G 1 395 ? 27.625  -23.956 59.915  1.00 37.78  ? 395 ASP G OD1 1 
ATOM   22027 O OD2 . ASP G 1 395 ? 25.740  -24.747 59.098  1.00 44.52  ? 395 ASP G OD2 1 
ATOM   22028 N N   . SER G 1 396 ? 27.326  -20.847 55.654  1.00 33.11  ? 396 SER G N   1 
ATOM   22029 C CA  . SER G 1 396 ? 27.724  -20.279 54.379  1.00 34.37  ? 396 SER G CA  1 
ATOM   22030 C C   . SER G 1 396 ? 28.062  -18.792 54.455  1.00 38.49  ? 396 SER G C   1 
ATOM   22031 O O   . SER G 1 396 ? 28.652  -18.256 53.505  1.00 32.47  ? 396 SER G O   1 
ATOM   22032 C CB  . SER G 1 396 ? 26.617  -20.509 53.342  1.00 31.70  ? 396 SER G CB  1 
ATOM   22033 O OG  . SER G 1 396 ? 25.373  -19.998 53.793  1.00 34.73  ? 396 SER G OG  1 
ATOM   22034 N N   . GLY G 1 397 ? 27.720  -18.115 55.553  1.00 35.70  ? 397 GLY G N   1 
ATOM   22035 C CA  . GLY G 1 397 ? 27.892  -16.673 55.595  1.00 30.37  ? 397 GLY G CA  1 
ATOM   22036 C C   . GLY G 1 397 ? 26.934  -15.900 54.717  1.00 30.34  ? 397 GLY G C   1 
ATOM   22037 O O   . GLY G 1 397 ? 27.183  -14.725 54.427  1.00 31.50  ? 397 GLY G O   1 
ATOM   22038 N N   . GLU G 1 398 ? 25.831  -16.520 54.299  1.00 26.69  ? 398 GLU G N   1 
ATOM   22039 C CA  . GLU G 1 398 ? 24.922  -15.965 53.308  1.00 28.89  ? 398 GLU G CA  1 
ATOM   22040 C C   . GLU G 1 398 ? 23.533  -15.755 53.900  1.00 28.30  ? 398 GLU G C   1 
ATOM   22041 O O   . GLU G 1 398 ? 23.076  -16.529 54.745  1.00 22.06  ? 398 GLU G O   1 
ATOM   22042 C CB  . GLU G 1 398 ? 24.792  -16.904 52.083  1.00 34.93  ? 398 GLU G CB  1 
ATOM   22043 C CG  . GLU G 1 398 ? 26.106  -17.370 51.435  1.00 36.04  ? 398 GLU G CG  1 
ATOM   22044 C CD  . GLU G 1 398 ? 26.357  -16.711 50.078  1.00 36.60  ? 398 GLU G CD  1 
ATOM   22045 O OE1 . GLU G 1 398 ? 25.385  -16.231 49.450  1.00 36.35  ? 398 GLU G OE1 1 
ATOM   22046 O OE2 . GLU G 1 398 ? 27.522  -16.678 49.633  1.00 38.64  ? 398 GLU G OE2 1 
ATOM   22047 N N   . GLY G 1 399 ? 22.845  -14.734 53.409  1.00 25.23  ? 399 GLY G N   1 
ATOM   22048 C CA  . GLY G 1 399 ? 21.461  -14.512 53.763  1.00 25.38  ? 399 GLY G CA  1 
ATOM   22049 C C   . GLY G 1 399 ? 21.278  -13.266 54.603  1.00 25.00  ? 399 GLY G C   1 
ATOM   22050 O O   . GLY G 1 399 ? 22.153  -12.404 54.701  1.00 27.51  ? 399 GLY G O   1 
ATOM   22051 N N   . ALA G 1 400 ? 20.108  -13.179 55.209  1.00 22.76  ? 400 ALA G N   1 
ATOM   22052 C CA  . ALA G 1 400 ? 19.634  -11.941 55.807  1.00 26.75  ? 400 ALA G CA  1 
ATOM   22053 C C   . ALA G 1 400 ? 19.364  -12.122 57.290  1.00 26.07  ? 400 ALA G C   1 
ATOM   22054 O O   . ALA G 1 400 ? 18.923  -13.189 57.726  1.00 23.19  ? 400 ALA G O   1 
ATOM   22055 C CB  . ALA G 1 400 ? 18.340  -11.452 55.134  1.00 27.97  ? 400 ALA G CB  1 
ATOM   22056 N N   . VAL G 1 401 ? 19.621  -11.058 58.051  1.00 26.84  ? 401 VAL G N   1 
ATOM   22057 C CA  . VAL G 1 401 ? 19.170  -10.944 59.430  1.00 28.35  ? 401 VAL G CA  1 
ATOM   22058 C C   . VAL G 1 401 ? 18.294  -9.700  59.542  1.00 26.04  ? 401 VAL G C   1 
ATOM   22059 O O   . VAL G 1 401 ? 18.230  -8.871  58.638  1.00 21.84  ? 401 VAL G O   1 
ATOM   22060 C CB  . VAL G 1 401 ? 20.334  -10.880 60.431  1.00 25.45  ? 401 VAL G CB  1 
ATOM   22061 C CG1 . VAL G 1 401 ? 21.285  -12.022 60.183  1.00 27.75  ? 401 VAL G CG1 1 
ATOM   22062 C CG2 . VAL G 1 401 ? 21.053  -9.570  60.318  1.00 21.36  ? 401 VAL G CG2 1 
ATOM   22063 N N   . VAL G 1 402 ? 17.638  -9.573  60.689  1.00 27.84  ? 402 VAL G N   1 
ATOM   22064 C CA  . VAL G 1 402 ? 16.562  -8.614  60.898  1.00 25.43  ? 402 VAL G CA  1 
ATOM   22065 C C   . VAL G 1 402 ? 17.089  -7.504  61.799  1.00 23.76  ? 402 VAL G C   1 
ATOM   22066 O O   . VAL G 1 402 ? 17.388  -7.729  62.977  1.00 24.41  ? 402 VAL G O   1 
ATOM   22067 C CB  . VAL G 1 402 ? 15.325  -9.295  61.506  1.00 29.85  ? 402 VAL G CB  1 
ATOM   22068 C CG1 . VAL G 1 402 ? 14.264  -8.276  61.899  1.00 26.06  ? 402 VAL G CG1 1 
ATOM   22069 C CG2 . VAL G 1 402 ? 14.754  -10.319 60.520  1.00 26.20  ? 402 VAL G CG2 1 
ATOM   22070 N N   . LEU G 1 403 ? 17.186  -6.299  61.262  1.00 20.54  ? 403 LEU G N   1 
ATOM   22071 C CA  . LEU G 1 403 ? 17.613  -5.177  62.082  1.00 29.09  ? 403 LEU G CA  1 
ATOM   22072 C C   . LEU G 1 403 ? 16.442  -4.483  62.746  1.00 27.79  ? 403 LEU G C   1 
ATOM   22073 O O   . LEU G 1 403 ? 16.627  -3.833  63.775  1.00 25.94  ? 403 LEU G O   1 
ATOM   22074 C CB  . LEU G 1 403 ? 18.406  -4.155  61.252  1.00 26.81  ? 403 LEU G CB  1 
ATOM   22075 C CG  . LEU G 1 403 ? 19.816  -4.574  60.802  1.00 29.07  ? 403 LEU G CG  1 
ATOM   22076 C CD1 . LEU G 1 403 ? 20.728  -3.381  60.748  1.00 24.92  ? 403 LEU G CD1 1 
ATOM   22077 C CD2 . LEU G 1 403 ? 20.395  -5.607  61.707  1.00 23.84  ? 403 LEU G CD2 1 
ATOM   22078 N N   . GLY G 1 404 ? 15.246  -4.622  62.193  1.00 27.06  ? 404 GLY G N   1 
ATOM   22079 C CA  . GLY G 1 404 ? 14.080  -3.981  62.770  1.00 29.89  ? 404 GLY G CA  1 
ATOM   22080 C C   . GLY G 1 404 ? 12.783  -4.554  62.246  1.00 31.65  ? 404 GLY G C   1 
ATOM   22081 O O   . GLY G 1 404 ? 12.665  -4.835  61.045  1.00 26.49  ? 404 GLY G O   1 
ATOM   22082 N N   . CYS G 1 405 ? 11.797  -4.720  63.132  1.00 24.87  ? 405 CYS G N   1 
ATOM   22083 C CA  . CYS G 1 405 ? 10.521  -5.270  62.709  1.00 26.03  ? 405 CYS G CA  1 
ATOM   22084 C C   . CYS G 1 405 ? 9.568   -4.205  62.201  1.00 29.56  ? 405 CYS G C   1 
ATOM   22085 O O   . CYS G 1 405 ? 8.717   -4.497  61.357  1.00 25.13  ? 405 CYS G O   1 
ATOM   22086 C CB  . CYS G 1 405 ? 9.872   -6.031  63.865  1.00 27.79  ? 405 CYS G CB  1 
ATOM   22087 S SG  . CYS G 1 405 ? 10.839  -7.513  64.295  1.00 30.66  ? 405 CYS G SG  1 
ATOM   22088 N N   . ASN G 1 406 ? 9.703   -2.971  62.674  1.00 30.73  ? 406 ASN G N   1 
ATOM   22089 C CA  . ASN G 1 406 ? 8.684   -1.974  62.383  1.00 31.36  ? 406 ASN G CA  1 
ATOM   22090 C C   . ASN G 1 406 ? 9.271   -0.583  62.587  1.00 34.38  ? 406 ASN G C   1 
ATOM   22091 O O   . ASN G 1 406 ? 8.921   0.125   63.538  1.00 30.86  ? 406 ASN G O   1 
ATOM   22092 C CB  . ASN G 1 406 ? 7.457   -2.216  63.268  1.00 23.81  ? 406 ASN G CB  1 
ATOM   22093 C CG  . ASN G 1 406 ? 6.390   -1.143  63.099  1.00 31.40  ? 406 ASN G CG  1 
ATOM   22094 O OD1 . ASN G 1 406 ? 6.195   -0.612  62.002  1.00 29.34  ? 406 ASN G OD1 1 
ATOM   22095 N ND2 . ASN G 1 406 ? 5.701   -0.812  64.195  1.00 25.53  ? 406 ASN G ND2 1 
ATOM   22096 N N   . SER G 1 407 ? 10.187  -0.199  61.705  1.00 30.30  ? 407 SER G N   1 
ATOM   22097 C CA  . SER G 1 407 ? 11.010  0.986   61.879  1.00 34.92  ? 407 SER G CA  1 
ATOM   22098 C C   . SER G 1 407 ? 10.516  2.119   60.993  1.00 31.63  ? 407 SER G C   1 
ATOM   22099 O O   . SER G 1 407 ? 9.982   1.887   59.907  1.00 33.21  ? 407 SER G O   1 
ATOM   22100 C CB  . SER G 1 407 ? 12.472  0.671   61.542  1.00 32.13  ? 407 SER G CB  1 
ATOM   22101 O OG  . SER G 1 407 ? 13.259  1.851   61.576  1.00 32.54  ? 407 SER G OG  1 
ATOM   22102 N N   . ASP G 1 408 ? 10.709  3.353   61.448  1.00 31.72  ? 408 ASP G N   1 
ATOM   22103 C CA  . ASP G 1 408 ? 10.409  4.472   60.566  1.00 39.53  ? 408 ASP G CA  1 
ATOM   22104 C C   . ASP G 1 408 ? 11.624  4.933   59.781  1.00 35.71  ? 408 ASP G C   1 
ATOM   22105 O O   . ASP G 1 408 ? 11.505  5.869   58.992  1.00 38.13  ? 408 ASP G O   1 
ATOM   22106 C CB  . ASP G 1 408 ? 9.786   5.649   61.330  1.00 40.02  ? 408 ASP G CB  1 
ATOM   22107 C CG  . ASP G 1 408 ? 10.290  5.770   62.740  1.00 46.90  ? 408 ASP G CG  1 
ATOM   22108 O OD1 . ASP G 1 408 ? 11.507  5.561   62.962  1.00 46.50  ? 408 ASP G OD1 1 
ATOM   22109 O OD2 . ASP G 1 408 ? 9.466   6.104   63.620  1.00 42.29  ? 408 ASP G OD2 1 
ATOM   22110 N N   . LEU G 1 409 ? 12.777  4.282   59.962  1.00 39.23  ? 409 LEU G N   1 
ATOM   22111 C CA  . LEU G 1 409 ? 13.908  4.420   59.055  1.00 34.43  ? 409 LEU G CA  1 
ATOM   22112 C C   . LEU G 1 409 ? 13.434  4.166   57.636  1.00 40.63  ? 409 LEU G C   1 
ATOM   22113 O O   . LEU G 1 409 ? 13.239  3.001   57.284  1.00 41.26  ? 409 LEU G O   1 
ATOM   22114 C CB  . LEU G 1 409 ? 14.993  3.408   59.407  1.00 35.15  ? 409 LEU G CB  1 
ATOM   22115 C CG  . LEU G 1 409 ? 16.453  3.826   59.430  1.00 35.01  ? 409 LEU G CG  1 
ATOM   22116 C CD1 . LEU G 1 409 ? 16.640  4.776   60.587  1.00 37.01  ? 409 LEU G CD1 1 
ATOM   22117 C CD2 . LEU G 1 409 ? 17.366  2.608   59.587  1.00 29.47  ? 409 LEU G CD2 1 
ATOM   22118 N N   . GLY G 1 410 ? 13.248  5.215   56.824  1.00 39.86  ? 410 GLY G N   1 
ATOM   22119 C CA  . GLY G 1 410 ? 12.643  5.064   55.512  1.00 51.81  ? 410 GLY G CA  1 
ATOM   22120 C C   . GLY G 1 410 ? 11.632  3.934   55.551  1.00 44.59  ? 410 GLY G C   1 
ATOM   22121 O O   . GLY G 1 410 ? 11.927  2.798   55.166  1.00 41.73  ? 410 GLY G O   1 
ATOM   22122 N N   . PRO G 1 411 ? 10.415  4.237   55.997  1.00 37.85  ? 411 PRO G N   1 
ATOM   22123 C CA  . PRO G 1 411 ? 9.729   3.354   56.955  1.00 36.77  ? 411 PRO G CA  1 
ATOM   22124 C C   . PRO G 1 411 ? 9.548   1.914   56.487  1.00 35.78  ? 411 PRO G C   1 
ATOM   22125 O O   . PRO G 1 411 ? 9.403   1.634   55.296  1.00 34.47  ? 411 PRO G O   1 
ATOM   22126 C CB  . PRO G 1 411 ? 8.377   4.042   57.151  1.00 40.58  ? 411 PRO G CB  1 
ATOM   22127 C CG  . PRO G 1 411 ? 8.159   4.780   55.870  1.00 42.75  ? 411 PRO G CG  1 
ATOM   22128 C CD  . PRO G 1 411 ? 9.508   5.212   55.378  1.00 44.66  ? 411 PRO G CD  1 
ATOM   22129 N N   . GLY G 1 412 ? 9.546   0.999   57.458  1.00 33.93  ? 412 GLY G N   1 
ATOM   22130 C CA  . GLY G 1 412 ? 9.326   -0.413  57.202  1.00 34.09  ? 412 GLY G CA  1 
ATOM   22131 C C   . GLY G 1 412 ? 10.122  -1.291  58.159  1.00 25.79  ? 412 GLY G C   1 
ATOM   22132 O O   . GLY G 1 412 ? 10.675  -0.836  59.149  1.00 25.04  ? 412 GLY G O   1 
ATOM   22133 N N   . ALA G 1 413 ? 10.145  -2.579  57.854  1.00 26.14  ? 413 ALA G N   1 
ATOM   22134 C CA  . ALA G 1 413 ? 11.043  -3.498  58.528  1.00 25.88  ? 413 ALA G CA  1 
ATOM   22135 C C   . ALA G 1 413 ? 12.380  -3.454  57.813  1.00 24.64  ? 413 ALA G C   1 
ATOM   22136 O O   . ALA G 1 413 ? 12.440  -3.289  56.592  1.00 24.13  ? 413 ALA G O   1 
ATOM   22137 C CB  . ALA G 1 413 ? 10.496  -4.924  58.539  1.00 29.30  ? 413 ALA G CB  1 
ATOM   22138 N N   . GLU G 1 414 ? 13.450  -3.579  58.581  1.00 26.41  ? 414 GLU G N   1 
ATOM   22139 C CA  . GLU G 1 414 ? 14.796  -3.353  58.076  1.00 27.79  ? 414 GLU G CA  1 
ATOM   22140 C C   . GLU G 1 414 ? 15.543  -4.673  58.116  1.00 24.68  ? 414 GLU G C   1 
ATOM   22141 O O   . GLU G 1 414 ? 15.664  -5.290  59.182  1.00 26.12  ? 414 GLU G O   1 
ATOM   22142 C CB  . GLU G 1 414 ? 15.523  -2.270  58.884  1.00 25.36  ? 414 GLU G CB  1 
ATOM   22143 C CG  . GLU G 1 414 ? 16.912  -1.934  58.306  1.00 29.53  ? 414 GLU G CG  1 
ATOM   22144 C CD  . GLU G 1 414 ? 17.792  -1.053  59.215  1.00 30.99  ? 414 GLU G CD  1 
ATOM   22145 O OE1 . GLU G 1 414 ? 17.460  -0.852  60.408  1.00 25.11  ? 414 GLU G OE1 1 
ATOM   22146 O OE2 . GLU G 1 414 ? 18.834  -0.558  58.721  1.00 29.85  ? 414 GLU G OE2 1 
ATOM   22147 N N   . LEU G 1 415 ? 15.996  -5.119  56.949  1.00 24.14  ? 415 LEU G N   1 
ATOM   22148 C CA  . LEU G 1 415 ? 16.804  -6.317  56.805  1.00 22.98  ? 415 LEU G CA  1 
ATOM   22149 C C   . LEU G 1 415 ? 18.183  -5.950  56.274  1.00 25.11  ? 415 LEU G C   1 
ATOM   22150 O O   . LEU G 1 415 ? 18.382  -4.915  55.641  1.00 21.94  ? 415 LEU G O   1 
ATOM   22151 C CB  . LEU G 1 415 ? 16.162  -7.337  55.856  1.00 25.69  ? 415 LEU G CB  1 
ATOM   22152 C CG  . LEU G 1 415 ? 14.662  -7.629  56.006  1.00 32.87  ? 415 LEU G CG  1 
ATOM   22153 C CD1 . LEU G 1 415 ? 14.233  -8.705  55.031  1.00 23.39  ? 415 LEU G CD1 1 
ATOM   22154 C CD2 . LEU G 1 415 ? 14.349  -8.037  57.429  1.00 31.87  ? 415 LEU G CD2 1 
ATOM   22155 N N   . LEU G 1 416 ? 19.133  -6.838  56.535  1.00 24.93  ? 416 LEU G N   1 
ATOM   22156 C CA  . LEU G 1 416 ? 20.505  -6.708  56.080  1.00 18.97  ? 416 LEU G CA  1 
ATOM   22157 C C   . LEU G 1 416 ? 20.888  -8.062  55.504  1.00 23.37  ? 416 LEU G C   1 
ATOM   22158 O O   . LEU G 1 416 ? 20.794  -9.079  56.204  1.00 25.99  ? 416 LEU G O   1 
ATOM   22159 C CB  . LEU G 1 416 ? 21.415  -6.299  57.254  1.00 18.47  ? 416 LEU G CB  1 
ATOM   22160 C CG  . LEU G 1 416 ? 22.927  -6.301  57.018  1.00 25.02  ? 416 LEU G CG  1 
ATOM   22161 C CD1 . LEU G 1 416 ? 23.305  -5.280  55.960  1.00 21.35  ? 416 LEU G CD1 1 
ATOM   22162 C CD2 . LEU G 1 416 ? 23.693  -6.066  58.303  1.00 21.92  ? 416 LEU G CD2 1 
ATOM   22163 N N   . VAL G 1 417 ? 21.295  -8.096  54.236  1.00 22.29  ? 417 VAL G N   1 
ATOM   22164 C CA  . VAL G 1 417 ? 21.553  -9.359  53.547  1.00 21.99  ? 417 VAL G CA  1 
ATOM   22165 C C   . VAL G 1 417 ? 23.005  -9.444  53.076  1.00 26.09  ? 417 VAL G C   1 
ATOM   22166 O O   . VAL G 1 417 ? 23.525  -8.514  52.444  1.00 28.06  ? 417 VAL G O   1 
ATOM   22167 C CB  . VAL G 1 417 ? 20.592  -9.568  52.367  1.00 23.65  ? 417 VAL G CB  1 
ATOM   22168 C CG1 . VAL G 1 417 ? 20.521  -11.059 52.056  1.00 27.41  ? 417 VAL G CG1 1 
ATOM   22169 C CG2 . VAL G 1 417 ? 19.188  -9.035  52.710  1.00 19.90  ? 417 VAL G CG2 1 
ATOM   22170 N N   . PHE G 1 418 ? 23.623  -10.596 53.321  1.00 24.19  ? 418 PHE G N   1 
ATOM   22171 C CA  . PHE G 1 418 ? 25.018  -10.875 53.004  1.00 27.19  ? 418 PHE G CA  1 
ATOM   22172 C C   . PHE G 1 418 ? 25.143  -11.931 51.916  1.00 26.58  ? 418 PHE G C   1 
ATOM   22173 O O   . PHE G 1 418 ? 24.405  -12.924 51.908  1.00 30.97  ? 418 PHE G O   1 
ATOM   22174 C CB  . PHE G 1 418 ? 25.763  -11.405 54.227  1.00 27.37  ? 418 PHE G CB  1 
ATOM   22175 C CG  . PHE G 1 418 ? 25.742  -10.486 55.391  1.00 27.88  ? 418 PHE G CG  1 
ATOM   22176 C CD1 . PHE G 1 418 ? 26.667  -9.471  55.489  1.00 23.72  ? 418 PHE G CD1 1 
ATOM   22177 C CD2 . PHE G 1 418 ? 24.807  -10.651 56.399  1.00 23.67  ? 418 PHE G CD2 1 
ATOM   22178 C CE1 . PHE G 1 418 ? 26.663  -8.618  56.578  1.00 25.76  ? 418 PHE G CE1 1 
ATOM   22179 C CE2 . PHE G 1 418 ? 24.794  -9.810  57.487  1.00 23.25  ? 418 PHE G CE2 1 
ATOM   22180 C CZ  . PHE G 1 418 ? 25.725  -8.792  57.581  1.00 25.47  ? 418 PHE G CZ  1 
ATOM   22181 N N   . SER G 1 419 ? 26.132  -11.758 51.049  1.00 26.54  ? 419 SER G N   1 
ATOM   22182 C CA  . SER G 1 419 ? 26.429  -12.762 50.043  1.00 30.76  ? 419 SER G CA  1 
ATOM   22183 C C   . SER G 1 419 ? 27.888  -12.660 49.639  1.00 32.68  ? 419 SER G C   1 
ATOM   22184 O O   . SER G 1 419 ? 28.464  -11.568 49.602  1.00 32.50  ? 419 SER G O   1 
ATOM   22185 C CB  . SER G 1 419 ? 25.546  -12.610 48.799  1.00 33.10  ? 419 SER G CB  1 
ATOM   22186 O OG  . SER G 1 419 ? 25.717  -13.716 47.918  1.00 34.17  ? 419 SER G OG  1 
ATOM   22187 N N   . LYS G 1 420 ? 28.475  -13.812 49.321  1.00 29.78  ? 420 LYS G N   1 
ATOM   22188 C CA  . LYS G 1 420 ? 29.763  -13.812 48.642  1.00 32.82  ? 420 LYS G CA  1 
ATOM   22189 C C   . LYS G 1 420 ? 29.645  -13.396 47.188  1.00 30.81  ? 420 LYS G C   1 
ATOM   22190 O O   . LYS G 1 420 ? 30.669  -13.318 46.501  1.00 36.58  ? 420 LYS G O   1 
ATOM   22191 C CB  . LYS G 1 420 ? 30.408  -15.203 48.714  1.00 33.50  ? 420 LYS G CB  1 
ATOM   22192 C CG  . LYS G 1 420 ? 30.635  -15.710 50.107  1.00 31.63  ? 420 LYS G CG  1 
ATOM   22193 C CD  . LYS G 1 420 ? 32.108  -15.801 50.429  1.00 33.52  ? 420 LYS G CD  1 
ATOM   22194 C CE  . LYS G 1 420 ? 32.336  -16.526 51.738  1.00 36.95  ? 420 LYS G CE  1 
ATOM   22195 N NZ  . LYS G 1 420 ? 32.263  -15.595 52.928  1.00 36.11  ? 420 LYS G NZ  1 
ATOM   22196 N N   . ASP G 1 421 ? 28.441  -13.133 46.692  1.00 29.51  ? 421 ASP G N   1 
ATOM   22197 C CA  . ASP G 1 421 ? 28.244  -12.936 45.264  1.00 35.14  ? 421 ASP G CA  1 
ATOM   22198 C C   . ASP G 1 421 ? 27.189  -11.862 45.031  1.00 35.53  ? 421 ASP G C   1 
ATOM   22199 O O   . ASP G 1 421 ? 26.074  -11.961 45.555  1.00 35.46  ? 421 ASP G O   1 
ATOM   22200 C CB  . ASP G 1 421 ? 27.845  -14.254 44.590  1.00 33.37  ? 421 ASP G CB  1 
ATOM   22201 C CG  . ASP G 1 421 ? 27.908  -14.174 43.090  1.00 39.67  ? 421 ASP G CG  1 
ATOM   22202 O OD1 . ASP G 1 421 ? 28.991  -14.421 42.520  1.00 45.93  ? 421 ASP G OD1 1 
ATOM   22203 O OD2 . ASP G 1 421 ? 26.877  -13.829 42.480  1.00 38.62  ? 421 ASP G OD2 1 
ATOM   22204 N N   . TRP G 1 422 ? 27.537  -10.834 44.243  1.00 37.13  ? 422 TRP G N   1 
ATOM   22205 C CA  . TRP G 1 422 ? 26.638  -9.689  44.111  1.00 36.16  ? 422 TRP G CA  1 
ATOM   22206 C C   . TRP G 1 422 ? 25.357  -10.081 43.382  1.00 38.35  ? 422 TRP G C   1 
ATOM   22207 O O   . TRP G 1 422 ? 24.251  -9.780  43.849  1.00 41.07  ? 422 TRP G O   1 
ATOM   22208 C CB  . TRP G 1 422 ? 27.330  -8.515  43.411  1.00 36.33  ? 422 TRP G CB  1 
ATOM   22209 C CG  . TRP G 1 422 ? 26.390  -7.329  43.168  1.00 43.28  ? 422 TRP G CG  1 
ATOM   22210 C CD1 . TRP G 1 422 ? 25.948  -6.864  41.955  1.00 46.30  ? 422 TRP G CD1 1 
ATOM   22211 C CD2 . TRP G 1 422 ? 25.760  -6.500  44.160  1.00 44.73  ? 422 TRP G CD2 1 
ATOM   22212 N NE1 . TRP G 1 422 ? 25.100  -5.794  42.134  1.00 46.28  ? 422 TRP G NE1 1 
ATOM   22213 C CE2 . TRP G 1 422 ? 24.966  -5.552  43.476  1.00 50.15  ? 422 TRP G CE2 1 
ATOM   22214 C CE3 . TRP G 1 422 ? 25.789  -6.465  45.561  1.00 46.28  ? 422 TRP G CE3 1 
ATOM   22215 C CZ2 . TRP G 1 422 ? 24.210  -4.577  44.149  1.00 52.93  ? 422 TRP G CZ2 1 
ATOM   22216 C CZ3 . TRP G 1 422 ? 25.031  -5.486  46.229  1.00 45.09  ? 422 TRP G CZ3 1 
ATOM   22217 C CH2 . TRP G 1 422 ? 24.256  -4.565  45.521  1.00 41.59  ? 422 TRP G CH2 1 
ATOM   22218 N N   . ASP G 1 423 ? 25.477  -10.768 42.248  1.00 36.25  ? 423 ASP G N   1 
ATOM   22219 C CA  . ASP G 1 423 ? 24.281  -11.227 41.556  1.00 37.54  ? 423 ASP G CA  1 
ATOM   22220 C C   . ASP G 1 423 ? 23.434  -12.110 42.455  1.00 36.61  ? 423 ASP G C   1 
ATOM   22221 O O   . ASP G 1 423 ? 22.210  -11.957 42.518  1.00 34.26  ? 423 ASP G O   1 
ATOM   22222 C CB  . ASP G 1 423 ? 24.672  -11.960 40.285  1.00 40.81  ? 423 ASP G CB  1 
ATOM   22223 C CG  . ASP G 1 423 ? 25.257  -11.029 39.263  1.00 42.80  ? 423 ASP G CG  1 
ATOM   22224 O OD1 . ASP G 1 423 ? 24.840  -9.846  39.238  1.00 42.20  ? 423 ASP G OD1 1 
ATOM   22225 O OD2 . ASP G 1 423 ? 26.160  -11.469 38.526  1.00 45.20  ? 423 ASP G OD2 1 
ATOM   22226 N N   . ARG G 1 424 ? 24.073  -13.016 43.187  1.00 36.19  ? 424 ARG G N   1 
ATOM   22227 C CA  . ARG G 1 424 ? 23.341  -13.817 44.157  1.00 37.09  ? 424 ARG G CA  1 
ATOM   22228 C C   . ARG G 1 424 ? 22.720  -12.943 45.245  1.00 38.57  ? 424 ARG G C   1 
ATOM   22229 O O   . ARG G 1 424 ? 21.628  -13.261 45.740  1.00 35.99  ? 424 ARG G O   1 
ATOM   22230 C CB  . ARG G 1 424 ? 24.285  -14.878 44.727  1.00 42.19  ? 424 ARG G CB  1 
ATOM   22231 C CG  . ARG G 1 424 ? 23.838  -15.627 45.972  1.00 45.94  ? 424 ARG G CG  1 
ATOM   22232 C CD  . ARG G 1 424 ? 24.499  -17.027 46.000  1.00 46.94  ? 424 ARG G CD  1 
ATOM   22233 N NE  . ARG G 1 424 ? 25.713  -17.046 46.809  1.00 39.84  ? 424 ARG G NE  1 
ATOM   22234 C CZ  . ARG G 1 424 ? 26.920  -17.337 46.343  1.00 42.01  ? 424 ARG G CZ  1 
ATOM   22235 N NH1 . ARG G 1 424 ? 27.108  -17.695 45.082  1.00 46.89  ? 424 ARG G NH1 1 
ATOM   22236 N NH2 . ARG G 1 424 ? 27.966  -17.256 47.157  1.00 43.20  ? 424 ARG G NH2 1 
ATOM   22237 N N   . LEU G 1 425 ? 23.371  -11.815 45.595  1.00 36.39  ? 425 LEU G N   1 
ATOM   22238 C CA  . LEU G 1 425 ? 22.772  -10.870 46.543  1.00 34.90  ? 425 LEU G CA  1 
ATOM   22239 C C   . LEU G 1 425 ? 21.518  -10.223 45.967  1.00 31.24  ? 425 LEU G C   1 
ATOM   22240 O O   . LEU G 1 425 ? 20.516  -10.065 46.672  1.00 29.39  ? 425 LEU G O   1 
ATOM   22241 C CB  . LEU G 1 425 ? 23.772  -9.781  46.948  1.00 31.34  ? 425 LEU G CB  1 
ATOM   22242 C CG  . LEU G 1 425 ? 23.641  -9.118  48.333  1.00 28.54  ? 425 LEU G CG  1 
ATOM   22243 C CD1 . LEU G 1 425 ? 24.706  -8.038  48.560  1.00 29.11  ? 425 LEU G CD1 1 
ATOM   22244 C CD2 . LEU G 1 425 ? 22.296  -8.526  48.587  1.00 30.78  ? 425 LEU G CD2 1 
ATOM   22245 N N   . THR G 1 426 ? 21.561  -9.809  44.701  1.00 34.23  ? 426 THR G N   1 
ATOM   22246 C CA  . THR G 1 426 ? 20.374  -9.217  44.088  1.00 34.73  ? 426 THR G CA  1 
ATOM   22247 C C   . THR G 1 426 ? 19.228  -10.221 44.046  1.00 33.44  ? 426 THR G C   1 
ATOM   22248 O O   . THR G 1 426 ? 18.089  -9.899  44.407  1.00 30.97  ? 426 THR G O   1 
ATOM   22249 C CB  . THR G 1 426 ? 20.713  -8.705  42.689  1.00 40.08  ? 426 THR G CB  1 
ATOM   22250 O OG1 . THR G 1 426 ? 21.771  -7.742  42.790  1.00 41.18  ? 426 THR G OG1 1 
ATOM   22251 C CG2 . THR G 1 426 ? 19.487  -8.046  42.026  1.00 35.68  ? 426 THR G CG2 1 
ATOM   22252 N N   . ALA G 1 427 ? 19.522  -11.460 43.642  1.00 32.45  ? 427 ALA G N   1 
ATOM   22253 C CA  . ALA G 1 427 ? 18.495  -12.499 43.589  1.00 37.28  ? 427 ALA G CA  1 
ATOM   22254 C C   . ALA G 1 427 ? 17.863  -12.720 44.964  1.00 35.26  ? 427 ALA G C   1 
ATOM   22255 O O   . ALA G 1 427 ? 16.633  -12.766 45.104  1.00 39.14  ? 427 ALA G O   1 
ATOM   22256 C CB  . ALA G 1 427 ? 19.111  -13.796 43.045  1.00 32.61  ? 427 ALA G CB  1 
ATOM   22257 N N   . MET G 1 428 ? 18.702  -12.836 45.993  1.00 31.46  ? 428 MET G N   1 
ATOM   22258 C CA  . MET G 1 428 ? 18.229  -12.975 47.366  1.00 34.92  ? 428 MET G CA  1 
ATOM   22259 C C   . MET G 1 428 ? 17.298  -11.831 47.759  1.00 33.46  ? 428 MET G C   1 
ATOM   22260 O O   . MET G 1 428 ? 16.278  -12.044 48.435  1.00 29.49  ? 428 MET G O   1 
ATOM   22261 C CB  . MET G 1 428 ? 19.435  -13.013 48.302  1.00 34.72  ? 428 MET G CB  1 
ATOM   22262 C CG  . MET G 1 428 ? 19.938  -14.373 48.708  1.00 30.01  ? 428 MET G CG  1 
ATOM   22263 S SD  . MET G 1 428 ? 21.421  -14.103 49.724  1.00 40.22  ? 428 MET G SD  1 
ATOM   22264 C CE  . MET G 1 428 ? 22.154  -15.735 49.677  1.00 41.75  ? 428 MET G CE  1 
ATOM   22265 N N   . LYS G 1 429 ? 17.645  -10.603 47.362  1.00 30.29  ? 429 LYS G N   1 
ATOM   22266 C CA  . LYS G 1 429 ? 16.813  -9.449  47.677  1.00 31.46  ? 429 LYS G CA  1 
ATOM   22267 C C   . LYS G 1 429 ? 15.476  -9.489  46.952  1.00 36.31  ? 429 LYS G C   1 
ATOM   22268 O O   . LYS G 1 429 ? 14.508  -8.882  47.432  1.00 32.37  ? 429 LYS G O   1 
ATOM   22269 C CB  . LYS G 1 429 ? 17.554  -8.145  47.349  1.00 32.14  ? 429 LYS G CB  1 
ATOM   22270 C CG  . LYS G 1 429 ? 18.226  -7.537  48.559  1.00 32.53  ? 429 LYS G CG  1 
ATOM   22271 C CD  . LYS G 1 429 ? 19.336  -6.564  48.223  1.00 36.60  ? 429 LYS G CD  1 
ATOM   22272 C CE  . LYS G 1 429 ? 18.784  -5.183  47.959  1.00 40.72  ? 429 LYS G CE  1 
ATOM   22273 N NZ  . LYS G 1 429 ? 19.527  -4.526  46.869  1.00 45.73  ? 429 LYS G NZ  1 
ATOM   22274 N N   . ASP G 1 430 ? 15.389  -10.204 45.824  1.00 34.91  ? 430 ASP G N   1 
ATOM   22275 C CA  . ASP G 1 430 ? 14.104  -10.306 45.138  1.00 39.43  ? 430 ASP G CA  1 
ATOM   22276 C C   . ASP G 1 430 ? 13.193  -11.333 45.792  1.00 35.11  ? 430 ASP G C   1 
ATOM   22277 O O   . ASP G 1 430 ? 11.989  -11.090 45.945  1.00 32.74  ? 430 ASP G O   1 
ATOM   22278 C CB  . ASP G 1 430 ? 14.306  -10.638 43.667  1.00 41.67  ? 430 ASP G CB  1 
ATOM   22279 C CG  . ASP G 1 430 ? 14.321  -9.406  42.811  1.00 53.85  ? 430 ASP G CG  1 
ATOM   22280 O OD1 . ASP G 1 430 ? 15.313  -9.215  42.069  1.00 55.65  ? 430 ASP G OD1 1 
ATOM   22281 O OD2 . ASP G 1 430 ? 13.343  -8.619  42.901  1.00 55.48  ? 430 ASP G OD2 1 
ATOM   22282 N N   . GLU G 1 431 ? 13.742  -12.477 46.196  1.00 34.19  ? 431 GLU G N   1 
ATOM   22283 C CA  . GLU G 1 431 ? 12.918  -13.444 46.910  1.00 36.95  ? 431 GLU G CA  1 
ATOM   22284 C C   . GLU G 1 431 ? 12.300  -12.818 48.155  1.00 33.64  ? 431 GLU G C   1 
ATOM   22285 O O   . GLU G 1 431 ? 11.139  -13.093 48.477  1.00 36.57  ? 431 GLU G O   1 
ATOM   22286 C CB  . GLU G 1 431 ? 13.737  -14.682 47.266  1.00 35.40  ? 431 GLU G CB  1 
ATOM   22287 C CG  . GLU G 1 431 ? 13.920  -15.633 46.107  1.00 39.70  ? 431 GLU G CG  1 
ATOM   22288 C CD  . GLU G 1 431 ? 12.723  -16.547 45.917  1.00 47.01  ? 431 GLU G CD  1 
ATOM   22289 O OE1 . GLU G 1 431 ? 11.714  -16.105 45.319  1.00 43.61  ? 431 GLU G OE1 1 
ATOM   22290 O OE2 . GLU G 1 431 ? 12.788  -17.709 46.381  1.00 53.31  ? 431 GLU G OE2 1 
ATOM   22291 N N   . ILE G 1 432 ? 13.037  -11.932 48.838  1.00 30.06  ? 432 ILE G N   1 
ATOM   22292 C CA  . ILE G 1 432 ? 12.471  -11.265 50.013  1.00 26.66  ? 432 ILE G CA  1 
ATOM   22293 C C   . ILE G 1 432 ? 11.286  -10.394 49.615  1.00 32.88  ? 432 ILE G C   1 
ATOM   22294 O O   . ILE G 1 432 ? 10.264  -10.353 50.310  1.00 27.65  ? 432 ILE G O   1 
ATOM   22295 C CB  . ILE G 1 432 ? 13.539  -10.439 50.746  1.00 25.24  ? 432 ILE G CB  1 
ATOM   22296 C CG1 . ILE G 1 432 ? 14.511  -11.363 51.481  1.00 31.59  ? 432 ILE G CG1 1 
ATOM   22297 C CG2 . ILE G 1 432 ? 12.858  -9.467  51.739  1.00 27.00  ? 432 ILE G CG2 1 
ATOM   22298 C CD1 . ILE G 1 432 ? 15.854  -10.698 51.814  1.00 27.24  ? 432 ILE G CD1 1 
ATOM   22299 N N   . ALA G 1 433 ? 11.405  -9.679  48.495  1.00 30.40  ? 433 ALA G N   1 
ATOM   22300 C CA  . ALA G 1 433 ? 10.315  -8.819  48.049  1.00 32.33  ? 433 ALA G CA  1 
ATOM   22301 C C   . ALA G 1 433 ? 9.067   -9.638  47.750  1.00 34.32  ? 433 ALA G C   1 
ATOM   22302 O O   . ALA G 1 433 ? 7.964   -9.300  48.194  1.00 36.55  ? 433 ALA G O   1 
ATOM   22303 C CB  . ALA G 1 433 ? 10.754  -8.017  46.823  1.00 29.06  ? 433 ALA G CB  1 
ATOM   22304 N N   . THR G 1 434 ? 9.234   -10.732 47.004  1.00 33.66  ? 434 THR G N   1 
ATOM   22305 C CA  . THR G 1 434 ? 8.161   -11.700 46.781  1.00 33.07  ? 434 THR G CA  1 
ATOM   22306 C C   . THR G 1 434 ? 7.631   -12.273 48.091  1.00 35.28  ? 434 THR G C   1 
ATOM   22307 O O   . THR G 1 434 ? 6.418   -12.447 48.266  1.00 35.33  ? 434 THR G O   1 
ATOM   22308 C CB  . THR G 1 434 ? 8.698   -12.836 45.915  1.00 34.52  ? 434 THR G CB  1 
ATOM   22309 O OG1 . THR G 1 434 ? 9.127   -12.302 44.662  1.00 42.25  ? 434 THR G OG1 1 
ATOM   22310 C CG2 . THR G 1 434 ? 7.633   -13.918 45.685  1.00 43.82  ? 434 THR G CG2 1 
ATOM   22311 N N   . THR G 1 435 ? 8.527   -12.610 49.015  1.00 32.90  ? 435 THR G N   1 
ATOM   22312 C CA  . THR G 1 435 ? 8.089   -13.391 50.162  1.00 36.07  ? 435 THR G CA  1 
ATOM   22313 C C   . THR G 1 435 ? 7.550   -12.528 51.302  1.00 33.83  ? 435 THR G C   1 
ATOM   22314 O O   . THR G 1 435 ? 6.553   -12.890 51.942  1.00 40.62  ? 435 THR G O   1 
ATOM   22315 C CB  . THR G 1 435 ? 9.240   -14.265 50.663  1.00 35.30  ? 435 THR G CB  1 
ATOM   22316 O OG1 . THR G 1 435 ? 9.420   -15.377 49.776  1.00 38.45  ? 435 THR G OG1 1 
ATOM   22317 C CG2 . THR G 1 435 ? 8.892   -14.817 51.991  1.00 38.06  ? 435 THR G CG2 1 
ATOM   22318 N N   . ALA G 1 436 ? 8.190   -11.396 51.572  1.00 29.75  ? 436 ALA G N   1 
ATOM   22319 C CA  . ALA G 1 436 ? 7.820   -10.543 52.688  1.00 31.21  ? 436 ALA G CA  1 
ATOM   22320 C C   . ALA G 1 436 ? 7.040   -9.312  52.262  1.00 30.05  ? 436 ALA G C   1 
ATOM   22321 O O   . ALA G 1 436 ? 6.324   -8.741  53.091  1.00 30.83  ? 436 ALA G O   1 
ATOM   22322 C CB  . ALA G 1 436 ? 9.074   -10.105 53.451  1.00 24.88  ? 436 ALA G CB  1 
ATOM   22323 N N   . GLY G 1 437 ? 7.160   -8.904  51.004  1.00 30.28  ? 437 GLY G N   1 
ATOM   22324 C CA  . GLY G 1 437 ? 6.525   -7.709  50.493  1.00 31.72  ? 437 GLY G CA  1 
ATOM   22325 C C   . GLY G 1 437 ? 7.379   -6.465  50.682  1.00 34.28  ? 437 GLY G C   1 
ATOM   22326 O O   . GLY G 1 437 ? 8.317   -6.429  51.480  1.00 33.16  ? 437 GLY G O   1 
ATOM   22327 N N   . THR G 1 438 ? 7.018   -5.415  49.935  1.00 35.58  ? 438 THR G N   1 
ATOM   22328 C CA  . THR G 1 438 ? 7.645   -4.103  50.057  1.00 38.43  ? 438 THR G CA  1 
ATOM   22329 C C   . THR G 1 438 ? 6.588   -3.013  50.132  1.00 36.74  ? 438 THR G C   1 
ATOM   22330 O O   . THR G 1 438 ? 5.496   -3.142  49.568  1.00 37.01  ? 438 THR G O   1 
ATOM   22331 C CB  . THR G 1 438 ? 8.566   -3.766  48.865  1.00 35.73  ? 438 THR G CB  1 
ATOM   22332 O OG1 . THR G 1 438 ? 7.802   -3.800  47.646  1.00 37.69  ? 438 THR G OG1 1 
ATOM   22333 C CG2 . THR G 1 438 ? 9.730   -4.754  48.776  1.00 47.52  ? 438 THR G CG2 1 
ATOM   22334 N N   . LEU G 1 439 ? 6.935   -1.930  50.821  1.00 31.11  ? 439 LEU G N   1 
ATOM   22335 C CA  . LEU G 1 439 ? 6.309   -0.642  50.571  1.00 38.41  ? 439 LEU G CA  1 
ATOM   22336 C C   . LEU G 1 439 ? 6.991   0.010   49.352  1.00 39.07  ? 439 LEU G C   1 
ATOM   22337 O O   . LEU G 1 439 ? 7.989   -0.492  48.831  1.00 42.61  ? 439 LEU G O   1 
ATOM   22338 C CB  . LEU G 1 439 ? 6.377   0.216   51.845  1.00 34.81  ? 439 LEU G CB  1 
ATOM   22339 C CG  . LEU G 1 439 ? 6.021   -0.578  53.127  1.00 32.47  ? 439 LEU G CG  1 
ATOM   22340 C CD1 . LEU G 1 439 ? 6.190   0.193   54.452  1.00 31.54  ? 439 LEU G CD1 1 
ATOM   22341 C CD2 . LEU G 1 439 ? 4.612   -1.160  53.069  1.00 29.53  ? 439 LEU G CD2 1 
ATOM   22342 N N   . SER G 1 440 ? 6.430   1.107   48.855  1.00 44.88  ? 440 SER G N   1 
ATOM   22343 C CA  . SER G 1 440 ? 7.040   1.775   47.673  1.00 42.73  ? 440 SER G CA  1 
ATOM   22344 C C   . SER G 1 440 ? 6.327   3.035   47.218  1.00 48.57  ? 440 SER G C   1 
ATOM   22345 O O   . SER G 1 440 ? 6.593   4.107   47.793  1.00 42.04  ? 440 SER G O   1 
ATOM   22346 C CB  . SER G 1 440 ? 7.133   0.843   46.462  1.00 32.16  ? 440 SER G CB  1 
ATOM   22347 O OG  . SER G 1 440 ? 6.031   -0.013  46.357  1.00 28.46  ? 440 SER G OG  1 
ATOM   22348 N N   . PRO H 1 2   ? 8.728   -42.960 43.418  1.00 33.42  ? 2   PRO H N   1 
ATOM   22349 C CA  . PRO H 1 2   ? 8.189   -42.284 44.608  1.00 40.39  ? 2   PRO H CA  1 
ATOM   22350 C C   . PRO H 1 2   ? 6.969   -43.015 45.174  1.00 39.23  ? 2   PRO H C   1 
ATOM   22351 O O   . PRO H 1 2   ? 6.565   -44.047 44.631  1.00 33.54  ? 2   PRO H O   1 
ATOM   22352 C CB  . PRO H 1 2   ? 7.796   -40.898 44.093  1.00 41.09  ? 2   PRO H CB  1 
ATOM   22353 C CG  . PRO H 1 2   ? 7.932   -40.956 42.607  1.00 40.59  ? 2   PRO H CG  1 
ATOM   22354 C CD  . PRO H 1 2   ? 8.842   -42.059 42.264  1.00 39.86  ? 2   PRO H CD  1 
ATOM   22355 N N   . LYS H 1 3   ? 6.380   -42.501 46.250  1.00 36.02  ? 3   LYS H N   1 
ATOM   22356 C CA  . LYS H 1 3   ? 5.268   -43.197 46.875  1.00 33.73  ? 3   LYS H CA  1 
ATOM   22357 C C   . LYS H 1 3   ? 4.149   -42.208 47.166  1.00 29.23  ? 3   LYS H C   1 
ATOM   22358 O O   . LYS H 1 3   ? 4.371   -41.003 47.271  1.00 33.97  ? 3   LYS H O   1 
ATOM   22359 C CB  . LYS H 1 3   ? 5.714   -43.935 48.150  1.00 27.34  ? 3   LYS H CB  1 
ATOM   22360 C CG  . LYS H 1 3   ? 6.032   -43.023 49.308  1.00 29.55  ? 3   LYS H CG  1 
ATOM   22361 C CD  . LYS H 1 3   ? 6.580   -43.773 50.494  1.00 24.14  ? 3   LYS H CD  1 
ATOM   22362 C CE  . LYS H 1 3   ? 6.822   -42.809 51.632  1.00 27.31  ? 3   LYS H CE  1 
ATOM   22363 N NZ  . LYS H 1 3   ? 8.093   -42.034 51.463  1.00 32.44  ? 3   LYS H NZ  1 
ATOM   22364 N N   . ILE H 1 4   ? 2.932   -42.733 47.260  1.00 29.43  ? 4   ILE H N   1 
ATOM   22365 C CA  . ILE H 1 4   ? 1.756   -41.963 47.649  1.00 23.72  ? 4   ILE H CA  1 
ATOM   22366 C C   . ILE H 1 4   ? 1.501   -42.222 49.132  1.00 23.48  ? 4   ILE H C   1 
ATOM   22367 O O   . ILE H 1 4   ? 1.113   -43.328 49.522  1.00 27.43  ? 4   ILE H O   1 
ATOM   22368 C CB  . ILE H 1 4   ? 0.544   -42.338 46.785  1.00 26.27  ? 4   ILE H CB  1 
ATOM   22369 C CG1 . ILE H 1 4   ? 0.828   -42.040 45.309  1.00 28.36  ? 4   ILE H CG1 1 
ATOM   22370 C CG2 . ILE H 1 4   ? -0.728  -41.633 47.254  1.00 26.45  ? 4   ILE H CG2 1 
ATOM   22371 C CD1 . ILE H 1 4   ? -0.323  -42.437 44.377  1.00 24.56  ? 4   ILE H CD1 1 
ATOM   22372 N N   . ILE H 1 5   ? 1.756   -41.219 49.968  1.00 25.87  ? 5   ILE H N   1 
ATOM   22373 C CA  . ILE H 1 5   ? 1.466   -41.295 51.398  1.00 20.99  ? 5   ILE H CA  1 
ATOM   22374 C C   . ILE H 1 5   ? -0.029  -41.068 51.588  1.00 24.41  ? 5   ILE H C   1 
ATOM   22375 O O   . ILE H 1 5   ? -0.555  -40.003 51.253  1.00 24.23  ? 5   ILE H O   1 
ATOM   22376 C CB  . ILE H 1 5   ? 2.291   -40.276 52.192  1.00 21.15  ? 5   ILE H CB  1 
ATOM   22377 C CG1 . ILE H 1 5   ? 3.784   -40.346 51.810  1.00 23.88  ? 5   ILE H CG1 1 
ATOM   22378 C CG2 . ILE H 1 5   ? 2.133   -40.519 53.698  1.00 20.26  ? 5   ILE H CG2 1 
ATOM   22379 C CD1 . ILE H 1 5   ? 4.622   -39.176 52.336  1.00 25.51  ? 5   ILE H CD1 1 
ATOM   22380 N N   . LEU H 1 6   ? -0.726  -42.081 52.098  1.00 25.28  ? 6   LEU H N   1 
ATOM   22381 C CA  . LEU H 1 6   ? -2.191  -42.133 52.046  1.00 29.49  ? 6   LEU H CA  1 
ATOM   22382 C C   . LEU H 1 6   ? -2.698  -42.441 53.446  1.00 28.23  ? 6   LEU H C   1 
ATOM   22383 O O   . LEU H 1 6   ? -3.003  -43.595 53.776  1.00 29.53  ? 6   LEU H O   1 
ATOM   22384 C CB  . LEU H 1 6   ? -2.639  -43.160 51.005  1.00 30.98  ? 6   LEU H CB  1 
ATOM   22385 C CG  . LEU H 1 6   ? -4.067  -43.335 50.503  1.00 28.48  ? 6   LEU H CG  1 
ATOM   22386 C CD1 . LEU H 1 6   ? -4.815  -44.375 51.295  1.00 30.05  ? 6   LEU H CD1 1 
ATOM   22387 C CD2 . LEU H 1 6   ? -4.773  -42.022 50.543  1.00 33.70  ? 6   LEU H CD2 1 
ATOM   22388 N N   . PRO H 1 7   ? -2.775  -41.431 54.308  1.00 30.13  ? 7   PRO H N   1 
ATOM   22389 C CA  . PRO H 1 7   ? -3.150  -41.668 55.719  1.00 26.83  ? 7   PRO H CA  1 
ATOM   22390 C C   . PRO H 1 7   ? -4.648  -41.902 55.847  1.00 32.19  ? 7   PRO H C   1 
ATOM   22391 O O   . PRO H 1 7   ? -5.409  -41.067 56.332  1.00 33.24  ? 7   PRO H O   1 
ATOM   22392 C CB  . PRO H 1 7   ? -2.686  -40.377 56.408  1.00 31.20  ? 7   PRO H CB  1 
ATOM   22393 C CG  . PRO H 1 7   ? -2.755  -39.315 55.340  1.00 35.00  ? 7   PRO H CG  1 
ATOM   22394 C CD  . PRO H 1 7   ? -2.574  -40.000 54.002  1.00 28.65  ? 7   PRO H CD  1 
ATOM   22395 N N   . ASN H 1 8   ? -5.091  -43.064 55.371  1.00 31.39  ? 8   ASN H N   1 
ATOM   22396 C CA  . ASN H 1 8   ? -6.505  -43.428 55.424  1.00 34.45  ? 8   ASN H CA  1 
ATOM   22397 C C   . ASN H 1 8   ? -6.888  -43.984 56.796  1.00 39.34  ? 8   ASN H C   1 
ATOM   22398 O O   . ASN H 1 8   ? -7.526  -45.035 56.884  1.00 38.92  ? 8   ASN H O   1 
ATOM   22399 C CB  . ASN H 1 8   ? -6.837  -44.431 54.307  1.00 29.12  ? 8   ASN H CB  1 
ATOM   22400 C CG  . ASN H 1 8   ? -6.027  -45.734 54.404  1.00 28.79  ? 8   ASN H CG  1 
ATOM   22401 O OD1 . ASN H 1 8   ? -4.924  -45.775 54.970  1.00 27.11  ? 8   ASN H OD1 1 
ATOM   22402 N ND2 . ASN H 1 8   ? -6.573  -46.801 53.830  1.00 29.29  ? 8   ASN H ND2 1 
ATOM   22403 N N   . PHE H 1 9   ? -6.543  -43.273 57.871  1.00 43.22  ? 9   PHE H N   1 
ATOM   22404 C CA  . PHE H 1 9   ? -6.681  -43.803 59.227  1.00 51.39  ? 9   PHE H CA  1 
ATOM   22405 C C   . PHE H 1 9   ? -8.014  -43.377 59.826  1.00 54.94  ? 9   PHE H C   1 
ATOM   22406 O O   . PHE H 1 9   ? -8.253  -42.181 60.025  1.00 54.00  ? 9   PHE H O   1 
ATOM   22407 C CB  . PHE H 1 9   ? -5.510  -43.375 60.124  1.00 53.83  ? 9   PHE H CB  1 
ATOM   22408 C CG  . PHE H 1 9   ? -5.473  -41.897 60.464  1.00 54.89  ? 9   PHE H CG  1 
ATOM   22409 C CD1 . PHE H 1 9   ? -5.062  -40.964 59.530  1.00 55.79  ? 9   PHE H CD1 1 
ATOM   22410 C CD2 . PHE H 1 9   ? -5.813  -41.452 61.734  1.00 64.65  ? 9   PHE H CD2 1 
ATOM   22411 C CE1 . PHE H 1 9   ? -5.016  -39.608 59.847  1.00 54.70  ? 9   PHE H CE1 1 
ATOM   22412 C CE2 . PHE H 1 9   ? -5.766  -40.099 62.058  1.00 63.91  ? 9   PHE H CE2 1 
ATOM   22413 C CZ  . PHE H 1 9   ? -5.365  -39.179 61.111  1.00 58.07  ? 9   PHE H CZ  1 
ATOM   22414 N N   . ARG H 1 10  ? -8.861  -44.375 60.105  1.00 60.25  ? 10  ARG H N   1 
ATOM   22415 C CA  . ARG H 1 10  ? -10.198 -44.313 60.733  1.00 61.69  ? 10  ARG H CA  1 
ATOM   22416 C C   . ARG H 1 10  ? -11.282 -44.568 59.694  1.00 68.21  ? 10  ARG H C   1 
ATOM   22417 O O   . ARG H 1 10  ? -12.325 -45.151 60.004  1.00 73.42  ? 10  ARG H O   1 
ATOM   22418 C CB  . ARG H 1 10  ? -10.473 -42.989 61.449  1.00 56.82  ? 10  ARG H CB  1 
ATOM   22419 C CG  . ARG H 1 10  ? -10.470 -43.095 62.954  1.00 59.11  ? 10  ARG H CG  1 
ATOM   22420 C CD  . ARG H 1 10  ? -10.714 -41.740 63.595  1.00 66.88  ? 10  ARG H CD  1 
ATOM   22421 N NE  . ARG H 1 10  ? -9.549  -40.867 63.514  1.00 72.62  ? 10  ARG H NE  1 
ATOM   22422 C CZ  . ARG H 1 10  ? -9.610  -39.541 63.532  1.00 72.75  ? 10  ARG H CZ  1 
ATOM   22423 N NH1 . ARG H 1 10  ? -10.767 -38.904 63.598  1.00 67.99  ? 10  ARG H NH1 1 
ATOM   22424 N NH2 . ARG H 1 10  ? -8.481  -38.838 63.481  1.00 73.48  ? 10  ARG H NH2 1 
ATOM   22425 N N   . SER H 1 29  ? -12.732 -29.047 58.874  1.00 61.04  ? 29  SER H N   1 
ATOM   22426 C CA  . SER H 1 29  ? -12.358 -27.934 59.744  1.00 61.17  ? 29  SER H CA  1 
ATOM   22427 C C   . SER H 1 29  ? -10.892 -27.552 59.503  1.00 61.32  ? 29  SER H C   1 
ATOM   22428 O O   . SER H 1 29  ? -10.286 -28.004 58.533  1.00 62.07  ? 29  SER H O   1 
ATOM   22429 C CB  . SER H 1 29  ? -12.616 -28.287 61.217  1.00 65.08  ? 29  SER H CB  1 
ATOM   22430 O OG  . SER H 1 29  ? -14.009 -28.251 61.519  1.00 53.56  ? 29  SER H OG  1 
ATOM   22431 N N   . SER H 1 30  ? -10.318 -26.725 60.379  1.00 62.80  ? 30  SER H N   1 
ATOM   22432 C CA  . SER H 1 30  ? -9.013  -26.116 60.136  1.00 60.82  ? 30  SER H CA  1 
ATOM   22433 C C   . SER H 1 30  ? -7.853  -26.867 60.796  1.00 55.83  ? 30  SER H C   1 
ATOM   22434 O O   . SER H 1 30  ? -6.719  -26.369 60.785  1.00 49.82  ? 30  SER H O   1 
ATOM   22435 C CB  . SER H 1 30  ? -9.027  -24.654 60.596  1.00 56.83  ? 30  SER H CB  1 
ATOM   22436 O OG  . SER H 1 30  ? -9.305  -24.554 61.991  1.00 56.66  ? 30  SER H OG  1 
ATOM   22437 N N   . THR H 1 31  ? -8.100  -28.047 61.362  1.00 55.06  ? 31  THR H N   1 
ATOM   22438 C CA  . THR H 1 31  ? -7.016  -28.824 61.949  1.00 47.14  ? 31  THR H CA  1 
ATOM   22439 C C   . THR H 1 31  ? -6.054  -29.313 60.874  1.00 44.24  ? 31  THR H C   1 
ATOM   22440 O O   . THR H 1 31  ? -6.424  -29.485 59.709  1.00 46.20  ? 31  THR H O   1 
ATOM   22441 C CB  . THR H 1 31  ? -7.557  -30.029 62.714  1.00 47.77  ? 31  THR H CB  1 
ATOM   22442 O OG1 . THR H 1 31  ? -8.604  -30.637 61.950  1.00 53.79  ? 31  THR H OG1 1 
ATOM   22443 C CG2 . THR H 1 31  ? -8.081  -29.613 64.095  1.00 47.41  ? 31  THR H CG2 1 
ATOM   22444 N N   . ASP H 1 32  ? -4.802  -29.531 61.278  1.00 37.26  ? 32  ASP H N   1 
ATOM   22445 C CA  . ASP H 1 32  ? -3.784  -30.131 60.425  1.00 37.88  ? 32  ASP H CA  1 
ATOM   22446 C C   . ASP H 1 32  ? -3.327  -31.461 61.005  1.00 35.03  ? 32  ASP H C   1 
ATOM   22447 O O   . ASP H 1 32  ? -2.137  -31.765 61.061  1.00 35.60  ? 32  ASP H O   1 
ATOM   22448 C CB  . ASP H 1 32  ? -2.607  -29.175 60.207  1.00 32.26  ? 32  ASP H CB  1 
ATOM   22449 C CG  . ASP H 1 32  ? -1.922  -28.748 61.503  1.00 39.20  ? 32  ASP H CG  1 
ATOM   22450 O OD1 . ASP H 1 32  ? -2.401  -29.092 62.603  1.00 36.07  ? 32  ASP H OD1 1 
ATOM   22451 O OD2 . ASP H 1 32  ? -0.896  -28.031 61.415  1.00 41.18  ? 32  ASP H OD2 1 
ATOM   22452 N N   . THR H 1 33  ? -4.292  -32.278 61.438  1.00 39.24  ? 33  THR H N   1 
ATOM   22453 C CA  . THR H 1 33  ? -3.960  -33.535 62.103  1.00 36.60  ? 33  THR H CA  1 
ATOM   22454 C C   . THR H 1 33  ? -3.156  -34.459 61.202  1.00 31.64  ? 33  THR H C   1 
ATOM   22455 O O   . THR H 1 33  ? -2.301  -35.204 61.691  1.00 33.21  ? 33  THR H O   1 
ATOM   22456 C CB  . THR H 1 33  ? -5.234  -34.230 62.584  1.00 35.50  ? 33  THR H CB  1 
ATOM   22457 O OG1 . THR H 1 33  ? -6.051  -33.287 63.281  1.00 39.30  ? 33  THR H OG1 1 
ATOM   22458 C CG2 . THR H 1 33  ? -4.900  -35.350 63.530  1.00 40.08  ? 33  THR H CG2 1 
ATOM   22459 N N   . THR H 1 34  ? -3.386  -34.421 59.895  1.00 30.63  ? 34  THR H N   1 
ATOM   22460 C CA  . THR H 1 34  ? -2.663  -35.329 59.013  1.00 36.25  ? 34  THR H CA  1 
ATOM   22461 C C   . THR H 1 34  ? -1.359  -34.747 58.483  1.00 32.88  ? 34  THR H C   1 
ATOM   22462 O O   . THR H 1 34  ? -0.641  -35.440 57.750  1.00 27.89  ? 34  THR H O   1 
ATOM   22463 C CB  . THR H 1 34  ? -3.548  -35.758 57.840  1.00 36.09  ? 34  THR H CB  1 
ATOM   22464 O OG1 . THR H 1 34  ? -3.932  -34.611 57.077  1.00 45.15  ? 34  THR H OG1 1 
ATOM   22465 C CG2 . THR H 1 34  ? -4.780  -36.466 58.350  1.00 35.68  ? 34  THR H CG2 1 
ATOM   22466 N N   . ALA H 1 35  ? -1.008  -33.514 58.865  1.00 29.89  ? 35  ALA H N   1 
ATOM   22467 C CA  . ALA H 1 35  ? 0.208   -32.911 58.327  1.00 29.04  ? 35  ALA H CA  1 
ATOM   22468 C C   . ALA H 1 35  ? 1.457   -33.622 58.816  1.00 24.41  ? 35  ALA H C   1 
ATOM   22469 O O   . ALA H 1 35  ? 2.468   -33.642 58.102  1.00 25.20  ? 35  ALA H O   1 
ATOM   22470 C CB  . ALA H 1 35  ? 0.270   -31.427 58.686  1.00 25.59  ? 35  ALA H CB  1 
ATOM   22471 N N   . ARG H 1 36  ? 1.415   -34.212 60.022  1.00 27.39  ? 36  ARG H N   1 
ATOM   22472 C CA  . ARG H 1 36  ? 2.595   -34.902 60.549  1.00 23.98  ? 36  ARG H CA  1 
ATOM   22473 C C   . ARG H 1 36  ? 3.166   -35.893 59.552  1.00 24.83  ? 36  ARG H C   1 
ATOM   22474 O O   . ARG H 1 36  ? 4.363   -36.189 59.588  1.00 22.68  ? 36  ARG H O   1 
ATOM   22475 C CB  . ARG H 1 36  ? 2.253   -35.631 61.842  1.00 25.28  ? 36  ARG H CB  1 
ATOM   22476 C CG  . ARG H 1 36  ? 1.334   -36.856 61.628  1.00 29.05  ? 36  ARG H CG  1 
ATOM   22477 C CD  . ARG H 1 36  ? 0.294   -36.915 62.732  1.00 28.45  ? 36  ARG H CD  1 
ATOM   22478 N NE  . ARG H 1 36  ? 0.919   -37.266 63.999  1.00 29.02  ? 36  ARG H NE  1 
ATOM   22479 C CZ  . ARG H 1 36  ? 1.339   -38.485 64.303  1.00 42.33  ? 36  ARG H CZ  1 
ATOM   22480 N NH1 . ARG H 1 36  ? 1.190   -39.497 63.461  1.00 51.85  ? 36  ARG H NH1 1 
ATOM   22481 N NH2 . ARG H 1 36  ? 1.923   -38.695 65.479  1.00 37.68  ? 36  ARG H NH2 1 
ATOM   22482 N N   . PHE H 1 37  ? 2.330   -36.416 58.652  1.00 24.43  ? 37  PHE H N   1 
ATOM   22483 C CA  . PHE H 1 37  ? 2.768   -37.493 57.774  1.00 25.33  ? 37  PHE H CA  1 
ATOM   22484 C C   . PHE H 1 37  ? 3.648   -36.993 56.640  1.00 23.33  ? 37  PHE H C   1 
ATOM   22485 O O   . PHE H 1 37  ? 4.266   -37.804 55.943  1.00 25.28  ? 37  PHE H O   1 
ATOM   22486 C CB  . PHE H 1 37  ? 1.538   -38.259 57.268  1.00 23.80  ? 37  PHE H CB  1 
ATOM   22487 C CG  . PHE H 1 37  ? 0.751   -38.917 58.387  1.00 28.96  ? 37  PHE H CG  1 
ATOM   22488 C CD1 . PHE H 1 37  ? 1.380   -39.795 59.268  1.00 23.41  ? 37  PHE H CD1 1 
ATOM   22489 C CD2 . PHE H 1 37  ? -0.578  -38.606 58.602  1.00 25.42  ? 37  PHE H CD2 1 
ATOM   22490 C CE1 . PHE H 1 37  ? 0.686   -40.382 60.320  1.00 27.29  ? 37  PHE H CE1 1 
ATOM   22491 C CE2 . PHE H 1 37  ? -1.293  -39.207 59.649  1.00 32.44  ? 37  PHE H CE2 1 
ATOM   22492 C CZ  . PHE H 1 37  ? -0.663  -40.082 60.514  1.00 26.01  ? 37  PHE H CZ  1 
ATOM   22493 N N   . LEU H 1 38  ? 3.742   -35.676 56.459  1.00 27.44  ? 38  LEU H N   1 
ATOM   22494 C CA  . LEU H 1 38  ? 4.751   -35.116 55.567  1.00 23.15  ? 38  LEU H CA  1 
ATOM   22495 C C   . LEU H 1 38  ? 6.147   -35.597 55.922  1.00 21.59  ? 38  LEU H C   1 
ATOM   22496 O O   . LEU H 1 38  ? 7.021   -35.651 55.057  1.00 27.13  ? 38  LEU H O   1 
ATOM   22497 C CB  . LEU H 1 38  ? 4.709   -33.591 55.627  1.00 23.89  ? 38  LEU H CB  1 
ATOM   22498 C CG  . LEU H 1 38  ? 4.123   -32.898 54.403  1.00 30.93  ? 38  LEU H CG  1 
ATOM   22499 C CD1 . LEU H 1 38  ? 4.404   -31.429 54.509  1.00 31.63  ? 38  LEU H CD1 1 
ATOM   22500 C CD2 . LEU H 1 38  ? 4.676   -33.478 53.106  1.00 29.67  ? 38  LEU H CD2 1 
ATOM   22501 N N   . TRP H 1 39  ? 6.396   -35.910 57.185  1.00 18.77  ? 39  TRP H N   1 
ATOM   22502 C CA  . TRP H 1 39  ? 7.736   -36.325 57.550  1.00 18.56  ? 39  TRP H CA  1 
ATOM   22503 C C   . TRP H 1 39  ? 8.106   -37.697 57.011  1.00 23.34  ? 39  TRP H C   1 
ATOM   22504 O O   . TRP H 1 39  ? 9.243   -38.132 57.235  1.00 22.16  ? 39  TRP H O   1 
ATOM   22505 C CB  . TRP H 1 39  ? 7.887   -36.304 59.064  1.00 23.36  ? 39  TRP H CB  1 
ATOM   22506 C CG  . TRP H 1 39  ? 7.945   -34.913 59.652  1.00 27.57  ? 39  TRP H CG  1 
ATOM   22507 C CD1 . TRP H 1 39  ? 6.889   -34.166 60.102  1.00 28.07  ? 39  TRP H CD1 1 
ATOM   22508 C CD2 . TRP H 1 39  ? 9.115   -34.107 59.846  1.00 20.47  ? 39  TRP H CD2 1 
ATOM   22509 N NE1 . TRP H 1 39  ? 7.336   -32.955 60.590  1.00 25.45  ? 39  TRP H NE1 1 
ATOM   22510 C CE2 . TRP H 1 39  ? 8.697   -32.892 60.431  1.00 27.08  ? 39  TRP H CE2 1 
ATOM   22511 C CE3 . TRP H 1 39  ? 10.471  -34.287 59.569  1.00 24.32  ? 39  TRP H CE3 1 
ATOM   22512 C CZ2 . TRP H 1 39  ? 9.595   -31.864 60.748  1.00 25.58  ? 39  TRP H CZ2 1 
ATOM   22513 C CZ3 . TRP H 1 39  ? 11.361  -33.276 59.893  1.00 21.73  ? 39  TRP H CZ3 1 
ATOM   22514 C CH2 . TRP H 1 39  ? 10.919  -32.079 60.473  1.00 25.28  ? 39  TRP H CH2 1 
ATOM   22515 N N   . HIS H 1 40  ? 7.177   -38.386 56.343  1.00 19.66  ? 40  HIS H N   1 
ATOM   22516 C CA  . HIS H 1 40  ? 7.454   -39.564 55.529  1.00 21.90  ? 40  HIS H CA  1 
ATOM   22517 C C   . HIS H 1 40  ? 7.980   -39.214 54.138  1.00 25.28  ? 40  HIS H C   1 
ATOM   22518 O O   . HIS H 1 40  ? 8.465   -40.110 53.437  1.00 23.66  ? 40  HIS H O   1 
ATOM   22519 C CB  . HIS H 1 40  ? 6.170   -40.399 55.354  1.00 23.46  ? 40  HIS H CB  1 
ATOM   22520 C CG  . HIS H 1 40  ? 5.841   -41.287 56.518  1.00 23.67  ? 40  HIS H CG  1 
ATOM   22521 N ND1 . HIS H 1 40  ? 6.647   -42.332 56.906  1.00 21.35  ? 40  HIS H ND1 1 
ATOM   22522 C CD2 . HIS H 1 40  ? 4.779   -41.301 57.357  1.00 24.08  ? 40  HIS H CD2 1 
ATOM   22523 C CE1 . HIS H 1 40  ? 6.107   -42.946 57.943  1.00 23.17  ? 40  HIS H CE1 1 
ATOM   22524 N NE2 . HIS H 1 40  ? 4.976   -42.338 58.241  1.00 25.30  ? 40  HIS H NE2 1 
ATOM   22525 N N   . ALA H 1 41  ? 7.894   -37.945 53.724  1.00 22.62  ? 41  ALA H N   1 
ATOM   22526 C CA  . ALA H 1 41  ? 8.056   -37.592 52.315  1.00 25.72  ? 41  ALA H CA  1 
ATOM   22527 C C   . ALA H 1 41  ? 9.505   -37.666 51.849  1.00 26.40  ? 41  ALA H C   1 
ATOM   22528 O O   . ALA H 1 41  ? 10.425  -37.219 52.534  1.00 27.19  ? 41  ALA H O   1 
ATOM   22529 C CB  . ALA H 1 41  ? 7.524   -36.180 52.063  1.00 26.38  ? 41  ALA H CB  1 
ATOM   22530 N N   . GLU H 1 42  ? 9.692   -38.216 50.664  1.00 28.81  ? 42  GLU H N   1 
ATOM   22531 C CA  . GLU H 1 42  ? 10.931  -38.174 49.911  1.00 29.61  ? 42  GLU H CA  1 
ATOM   22532 C C   . GLU H 1 42  ? 10.675  -37.406 48.620  1.00 34.11  ? 42  GLU H C   1 
ATOM   22533 O O   . GLU H 1 42  ? 9.548   -36.997 48.340  1.00 35.40  ? 42  GLU H O   1 
ATOM   22534 C CB  . GLU H 1 42  ? 11.438  -39.589 49.633  1.00 33.29  ? 42  GLU H CB  1 
ATOM   22535 C CG  . GLU H 1 42  ? 12.209  -40.201 50.794  1.00 35.35  ? 42  GLU H CG  1 
ATOM   22536 C CD  . GLU H 1 42  ? 12.451  -41.684 50.603  1.00 56.99  ? 42  GLU H CD  1 
ATOM   22537 O OE1 . GLU H 1 42  ? 11.981  -42.477 51.452  1.00 59.34  ? 42  GLU H OE1 1 
ATOM   22538 O OE2 . GLU H 1 42  ? 13.100  -42.064 49.594  1.00 63.04  ? 42  GLU H OE2 1 
ATOM   22539 N N   . ASP H 1 43  ? 11.735  -37.209 47.836  1.00 39.37  ? 43  ASP H N   1 
ATOM   22540 C CA  . ASP H 1 43  ? 11.632  -36.515 46.555  1.00 31.92  ? 43  ASP H CA  1 
ATOM   22541 C C   . ASP H 1 43  ? 10.563  -37.141 45.665  1.00 36.06  ? 43  ASP H C   1 
ATOM   22542 O O   . ASP H 1 43  ? 10.535  -38.359 45.465  1.00 36.95  ? 43  ASP H O   1 
ATOM   22543 C CB  . ASP H 1 43  ? 12.980  -36.549 45.826  1.00 36.27  ? 43  ASP H CB  1 
ATOM   22544 C CG  . ASP H 1 43  ? 13.828  -35.314 46.082  1.00 42.23  ? 43  ASP H CG  1 
ATOM   22545 O OD1 . ASP H 1 43  ? 13.729  -34.722 47.181  1.00 44.42  ? 43  ASP H OD1 1 
ATOM   22546 O OD2 . ASP H 1 43  ? 14.590  -34.920 45.171  1.00 46.05  ? 43  ASP H OD2 1 
ATOM   22547 N N   . GLY H 1 44  ? 9.686   -36.296 45.118  1.00 36.26  ? 44  GLY H N   1 
ATOM   22548 C CA  . GLY H 1 44  ? 8.665   -36.739 44.200  1.00 35.13  ? 44  GLY H CA  1 
ATOM   22549 C C   . GLY H 1 44  ? 7.410   -37.288 44.840  1.00 38.23  ? 44  GLY H C   1 
ATOM   22550 O O   . GLY H 1 44  ? 6.409   -37.460 44.132  1.00 33.21  ? 44  GLY H O   1 
ATOM   22551 N N   . ASP H 1 45  ? 7.413   -37.543 46.154  1.00 39.28  ? 45  ASP H N   1 
ATOM   22552 C CA  . ASP H 1 45  ? 6.265   -38.162 46.810  1.00 34.83  ? 45  ASP H CA  1 
ATOM   22553 C C   . ASP H 1 45  ? 5.025   -37.273 46.741  1.00 32.53  ? 45  ASP H C   1 
ATOM   22554 O O   . ASP H 1 45  ? 5.088   -36.064 46.488  1.00 34.95  ? 45  ASP H O   1 
ATOM   22555 C CB  . ASP H 1 45  ? 6.566   -38.481 48.271  1.00 33.05  ? 45  ASP H CB  1 
ATOM   22556 C CG  . ASP H 1 45  ? 7.507   -39.654 48.429  1.00 31.94  ? 45  ASP H CG  1 
ATOM   22557 O OD1 . ASP H 1 45  ? 7.854   -40.283 47.410  1.00 35.97  ? 45  ASP H OD1 1 
ATOM   22558 O OD2 . ASP H 1 45  ? 7.890   -39.955 49.577  1.00 26.93  ? 45  ASP H OD2 1 
ATOM   22559 N N   . VAL H 1 46  ? 3.881   -37.912 46.955  1.00 33.20  ? 46  VAL H N   1 
ATOM   22560 C CA  . VAL H 1 46  ? 2.577   -37.266 46.998  1.00 29.82  ? 46  VAL H CA  1 
ATOM   22561 C C   . VAL H 1 46  ? 2.009   -37.523 48.381  1.00 31.58  ? 46  VAL H C   1 
ATOM   22562 O O   . VAL H 1 46  ? 1.978   -38.676 48.838  1.00 29.89  ? 46  VAL H O   1 
ATOM   22563 C CB  . VAL H 1 46  ? 1.628   -37.824 45.912  1.00 32.06  ? 46  VAL H CB  1 
ATOM   22564 C CG1 . VAL H 1 46  ? 0.141   -37.574 46.279  1.00 30.08  ? 46  VAL H CG1 1 
ATOM   22565 C CG2 . VAL H 1 46  ? 1.955   -37.247 44.550  1.00 36.01  ? 46  VAL H CG2 1 
ATOM   22566 N N   . LEU H 1 47  ? 1.572   -36.464 49.052  1.00 27.93  ? 47  LEU H N   1 
ATOM   22567 C CA  . LEU H 1 47  ? 0.880   -36.609 50.322  1.00 25.45  ? 47  LEU H CA  1 
ATOM   22568 C C   . LEU H 1 47  ? -0.576  -36.253 50.098  1.00 31.42  ? 47  LEU H C   1 
ATOM   22569 O O   . LEU H 1 47  ? -0.883  -35.118 49.726  1.00 32.67  ? 47  LEU H O   1 
ATOM   22570 C CB  . LEU H 1 47  ? 1.497   -35.739 51.413  1.00 24.96  ? 47  LEU H CB  1 
ATOM   22571 C CG  . LEU H 1 47  ? 0.695   -35.758 52.721  1.00 29.35  ? 47  LEU H CG  1 
ATOM   22572 C CD1 . LEU H 1 47  ? 0.414   -37.185 53.237  1.00 29.05  ? 47  LEU H CD1 1 
ATOM   22573 C CD2 . LEU H 1 47  ? 1.397   -34.967 53.795  1.00 29.00  ? 47  LEU H CD2 1 
ATOM   22574 N N   . VAL H 1 48  ? -1.457  -37.227 50.296  1.00 28.63  ? 48  VAL H N   1 
ATOM   22575 C CA  . VAL H 1 48  ? -2.898  -37.006 50.238  1.00 33.21  ? 48  VAL H CA  1 
ATOM   22576 C C   . VAL H 1 48  ? -3.346  -36.629 51.641  1.00 36.56  ? 48  VAL H C   1 
ATOM   22577 O O   . VAL H 1 48  ? -3.066  -37.346 52.605  1.00 39.70  ? 48  VAL H O   1 
ATOM   22578 C CB  . VAL H 1 48  ? -3.644  -38.253 49.733  1.00 29.51  ? 48  VAL H CB  1 
ATOM   22579 C CG1 . VAL H 1 48  ? -5.127  -38.005 49.686  1.00 28.24  ? 48  VAL H CG1 1 
ATOM   22580 C CG2 . VAL H 1 48  ? -3.147  -38.660 48.359  1.00 31.94  ? 48  VAL H CG2 1 
ATOM   22581 N N   . ILE H 1 49  ? -4.001  -35.486 51.781  1.00 40.61  ? 49  ILE H N   1 
ATOM   22582 C CA  . ILE H 1 49  ? -4.503  -35.162 53.109  1.00 42.96  ? 49  ILE H CA  1 
ATOM   22583 C C   . ILE H 1 49  ? -5.996  -34.851 53.047  1.00 46.73  ? 49  ILE H C   1 
ATOM   22584 O O   . ILE H 1 49  ? -6.495  -34.362 52.018  1.00 45.62  ? 49  ILE H O   1 
ATOM   22585 C CB  . ILE H 1 49  ? -3.654  -34.055 53.768  1.00 42.31  ? 49  ILE H CB  1 
ATOM   22586 C CG1 . ILE H 1 49  ? -3.378  -32.844 52.873  1.00 46.28  ? 49  ILE H CG1 1 
ATOM   22587 C CG2 . ILE H 1 49  ? -2.323  -34.616 54.201  1.00 46.10  ? 49  ILE H CG2 1 
ATOM   22588 C CD1 . ILE H 1 49  ? -4.556  -32.110 52.404  1.00 48.51  ? 49  ILE H CD1 1 
ATOM   22589 N N   . PRO H 1 50  ? -6.760  -35.189 54.097  1.00 43.02  ? 50  PRO H N   1 
ATOM   22590 C CA  . PRO H 1 50  ? -8.176  -34.819 54.127  1.00 45.50  ? 50  PRO H CA  1 
ATOM   22591 C C   . PRO H 1 50  ? -8.391  -33.470 54.789  1.00 44.32  ? 50  PRO H C   1 
ATOM   22592 O O   . PRO H 1 50  ? -9.418  -32.825 54.564  1.00 45.59  ? 50  PRO H O   1 
ATOM   22593 C CB  . PRO H 1 50  ? -8.822  -35.956 54.930  1.00 41.21  ? 50  PRO H CB  1 
ATOM   22594 C CG  . PRO H 1 50  ? -7.717  -36.581 55.704  1.00 41.26  ? 50  PRO H CG  1 
ATOM   22595 C CD  . PRO H 1 50  ? -6.393  -36.049 55.231  1.00 39.96  ? 50  PRO H CD  1 
ATOM   22596 N N   . ASP H 1 51  ? -7.431  -33.023 55.598  1.00 41.55  ? 51  ASP H N   1 
ATOM   22597 C CA  . ASP H 1 51  ? -7.591  -31.738 56.266  1.00 43.75  ? 51  ASP H CA  1 
ATOM   22598 C C   . ASP H 1 51  ? -6.936  -30.620 55.471  1.00 46.10  ? 51  ASP H C   1 
ATOM   22599 O O   . ASP H 1 51  ? -6.890  -30.641 54.236  1.00 47.73  ? 51  ASP H O   1 
ATOM   22600 C CB  . ASP H 1 51  ? -6.962  -31.737 57.657  1.00 46.74  ? 51  ASP H CB  1 
ATOM   22601 C CG  . ASP H 1 51  ? -7.064  -33.066 58.356  1.00 50.59  ? 51  ASP H CG  1 
ATOM   22602 O OD1 . ASP H 1 51  ? -8.191  -33.522 58.654  1.00 55.40  ? 51  ASP H OD1 1 
ATOM   22603 O OD2 . ASP H 1 51  ? -5.992  -33.632 58.642  1.00 48.83  ? 51  ASP H OD2 1 
ATOM   22604 N N   . THR H 1 52  ? -6.406  -29.652 56.202  1.00 42.37  ? 52  THR H N   1 
ATOM   22605 C CA  . THR H 1 52  ? -5.635  -28.552 55.662  1.00 44.29  ? 52  THR H CA  1 
ATOM   22606 C C   . THR H 1 52  ? -4.287  -28.516 56.357  1.00 43.89  ? 52  THR H C   1 
ATOM   22607 O O   . THR H 1 52  ? -4.141  -28.979 57.489  1.00 43.52  ? 52  THR H O   1 
ATOM   22608 C CB  . THR H 1 52  ? -6.340  -27.215 55.874  1.00 47.74  ? 52  THR H CB  1 
ATOM   22609 O OG1 . THR H 1 52  ? -5.480  -26.154 55.432  1.00 52.59  ? 52  THR H OG1 1 
ATOM   22610 C CG2 . THR H 1 52  ? -6.667  -27.036 57.357  1.00 47.29  ? 52  THR H CG2 1 
ATOM   22611 N N   . VAL H 1 53  ? -3.304  -27.943 55.677  1.00 44.34  ? 53  VAL H N   1 
ATOM   22612 C CA  . VAL H 1 53  ? -1.952  -27.835 56.201  1.00 40.89  ? 53  VAL H CA  1 
ATOM   22613 C C   . VAL H 1 53  ? -1.508  -26.382 56.106  1.00 39.65  ? 53  VAL H C   1 
ATOM   22614 O O   . VAL H 1 53  ? -1.827  -25.697 55.128  1.00 39.56  ? 53  VAL H O   1 
ATOM   22615 C CB  . VAL H 1 53  ? -1.004  -28.770 55.427  1.00 37.44  ? 53  VAL H CB  1 
ATOM   22616 C CG1 . VAL H 1 53  ? -1.110  -28.503 53.947  1.00 42.86  ? 53  VAL H CG1 1 
ATOM   22617 C CG2 . VAL H 1 53  ? 0.438   -28.596 55.896  1.00 44.06  ? 53  VAL H CG2 1 
ATOM   22618 N N   . ASP H 1 54  ? -0.812  -25.902 57.139  1.00 37.79  ? 54  ASP H N   1 
ATOM   22619 C CA  . ASP H 1 54  ? -0.127  -24.619 57.056  1.00 33.69  ? 54  ASP H CA  1 
ATOM   22620 C C   . ASP H 1 54  ? 0.710   -24.575 55.777  1.00 37.18  ? 54  ASP H C   1 
ATOM   22621 O O   . ASP H 1 54  ? 1.467   -25.520 55.500  1.00 34.92  ? 54  ASP H O   1 
ATOM   22622 C CB  . ASP H 1 54  ? 0.751   -24.398 58.293  1.00 39.10  ? 54  ASP H CB  1 
ATOM   22623 C CG  . ASP H 1 54  ? 1.248   -22.950 58.433  1.00 39.01  ? 54  ASP H CG  1 
ATOM   22624 O OD1 . ASP H 1 54  ? 1.765   -22.382 57.438  1.00 39.81  ? 54  ASP H OD1 1 
ATOM   22625 O OD2 . ASP H 1 54  ? 1.144   -22.392 59.552  1.00 30.12  ? 54  ASP H OD2 1 
ATOM   22626 N N   . PRO H 1 55  ? 0.557   -23.548 54.943  1.00 37.04  ? 55  PRO H N   1 
ATOM   22627 C CA  . PRO H 1 55  ? 1.157   -23.611 53.602  1.00 35.50  ? 55  PRO H CA  1 
ATOM   22628 C C   . PRO H 1 55  ? 2.672   -23.495 53.616  1.00 34.07  ? 55  PRO H C   1 
ATOM   22629 O O   . PRO H 1 55  ? 3.312   -23.870 52.627  1.00 33.47  ? 55  PRO H O   1 
ATOM   22630 C CB  . PRO H 1 55  ? 0.499   -22.431 52.875  1.00 28.87  ? 55  PRO H CB  1 
ATOM   22631 C CG  . PRO H 1 55  ? -0.769  -22.222 53.622  1.00 36.74  ? 55  PRO H CG  1 
ATOM   22632 C CD  . PRO H 1 55  ? -0.404  -22.443 55.047  1.00 35.95  ? 55  PRO H CD  1 
ATOM   22633 N N   . ASP H 1 56  ? 3.255   -22.999 54.712  1.00 35.02  ? 56  ASP H N   1 
ATOM   22634 C CA  . ASP H 1 56  ? 4.698   -23.037 54.922  1.00 29.36  ? 56  ASP H CA  1 
ATOM   22635 C C   . ASP H 1 56  ? 5.188   -24.389 55.412  1.00 32.88  ? 56  ASP H C   1 
ATOM   22636 O O   . ASP H 1 56  ? 6.394   -24.669 55.309  1.00 33.18  ? 56  ASP H O   1 
ATOM   22637 C CB  . ASP H 1 56  ? 5.105   -21.971 55.931  1.00 30.58  ? 56  ASP H CB  1 
ATOM   22638 C CG  . ASP H 1 56  ? 5.348   -20.635 55.285  1.00 33.30  ? 56  ASP H CG  1 
ATOM   22639 O OD1 . ASP H 1 56  ? 5.154   -20.521 54.055  1.00 40.72  ? 56  ASP H OD1 1 
ATOM   22640 O OD2 . ASP H 1 56  ? 5.782   -19.715 55.988  1.00 36.03  ? 56  ASP H OD2 1 
ATOM   22641 N N   . PHE H 1 57  ? 4.283   -25.232 55.916  1.00 25.75  ? 57  PHE H N   1 
ATOM   22642 C CA  . PHE H 1 57  ? 4.699   -26.491 56.536  1.00 34.77  ? 57  PHE H CA  1 
ATOM   22643 C C   . PHE H 1 57  ? 5.459   -27.442 55.608  1.00 30.92  ? 57  PHE H C   1 
ATOM   22644 O O   . PHE H 1 57  ? 6.443   -28.047 56.074  1.00 28.37  ? 57  PHE H O   1 
ATOM   22645 C CB  . PHE H 1 57  ? 3.475   -27.196 57.145  1.00 29.44  ? 57  PHE H CB  1 
ATOM   22646 C CG  . PHE H 1 57  ? 3.818   -28.372 57.995  1.00 28.23  ? 57  PHE H CG  1 
ATOM   22647 C CD1 . PHE H 1 57  ? 4.309   -28.198 59.260  1.00 28.25  ? 57  PHE H CD1 1 
ATOM   22648 C CD2 . PHE H 1 57  ? 3.650   -29.665 57.516  1.00 31.94  ? 57  PHE H CD2 1 
ATOM   22649 C CE1 . PHE H 1 57  ? 4.636   -29.281 60.047  1.00 27.17  ? 57  PHE H CE1 1 
ATOM   22650 C CE2 . PHE H 1 57  ? 3.962   -30.756 58.301  1.00 31.04  ? 57  PHE H CE2 1 
ATOM   22651 C CZ  . PHE H 1 57  ? 4.464   -30.563 59.568  1.00 28.26  ? 57  PHE H CZ  1 
ATOM   22652 N N   . PRO H 1 58  ? 5.064   -27.664 54.346  1.00 29.23  ? 58  PRO H N   1 
ATOM   22653 C CA  . PRO H 1 58  ? 5.907   -28.525 53.491  1.00 26.39  ? 58  PRO H CA  1 
ATOM   22654 C C   . PRO H 1 58  ? 7.331   -28.014 53.357  1.00 31.52  ? 58  PRO H C   1 
ATOM   22655 O O   . PRO H 1 58  ? 8.288   -28.784 53.548  1.00 32.46  ? 58  PRO H O   1 
ATOM   22656 C CB  . PRO H 1 58  ? 5.164   -28.545 52.142  1.00 32.51  ? 58  PRO H CB  1 
ATOM   22657 C CG  . PRO H 1 58  ? 3.758   -28.159 52.446  1.00 32.44  ? 58  PRO H CG  1 
ATOM   22658 C CD  . PRO H 1 58  ? 3.741   -27.393 53.747  1.00 30.21  ? 58  PRO H CD  1 
ATOM   22659 N N   . GLY H 1 59  ? 7.504   -26.726 53.053  1.00 30.56  ? 59  GLY H N   1 
ATOM   22660 C CA  . GLY H 1 59  ? 8.851   -26.187 52.930  1.00 30.81  ? 59  GLY H CA  1 
ATOM   22661 C C   . GLY H 1 59  ? 9.673   -26.320 54.199  1.00 24.53  ? 59  GLY H C   1 
ATOM   22662 O O   . GLY H 1 59  ? 10.886  -26.517 54.139  1.00 29.24  ? 59  GLY H O   1 
ATOM   22663 N N   . TYR H 1 60  ? 9.030   -26.204 55.359  1.00 26.72  ? 60  TYR H N   1 
ATOM   22664 C CA  . TYR H 1 60  ? 9.741   -26.354 56.619  1.00 23.79  ? 60  TYR H CA  1 
ATOM   22665 C C   . TYR H 1 60  ? 10.216  -27.788 56.805  1.00 27.38  ? 60  TYR H C   1 
ATOM   22666 O O   . TYR H 1 60  ? 11.363  -28.018 57.207  1.00 27.01  ? 60  TYR H O   1 
ATOM   22667 C CB  . TYR H 1 60  ? 8.843   -25.922 57.778  1.00 25.89  ? 60  TYR H CB  1 
ATOM   22668 C CG  . TYR H 1 60  ? 9.230   -26.570 59.089  1.00 27.21  ? 60  TYR H CG  1 
ATOM   22669 C CD1 . TYR H 1 60  ? 10.384  -26.178 59.760  1.00 18.97  ? 60  TYR H CD1 1 
ATOM   22670 C CD2 . TYR H 1 60  ? 8.446   -27.571 59.650  1.00 25.35  ? 60  TYR H CD2 1 
ATOM   22671 C CE1 . TYR H 1 60  ? 10.747  -26.768 60.935  1.00 27.44  ? 60  TYR H CE1 1 
ATOM   22672 C CE2 . TYR H 1 60  ? 8.809   -28.173 60.848  1.00 22.58  ? 60  TYR H CE2 1 
ATOM   22673 C CZ  . TYR H 1 60  ? 9.962   -27.770 61.481  1.00 23.62  ? 60  TYR H CZ  1 
ATOM   22674 O OH  . TYR H 1 60  ? 10.343  -28.344 62.678  1.00 25.13  ? 60  TYR H OH  1 
ATOM   22675 N N   . VAL H 1 61  ? 9.350   -28.760 56.493  1.00 26.99  ? 61  VAL H N   1 
ATOM   22676 C CA  . VAL H 1 61  ? 9.696   -30.175 56.621  1.00 27.44  ? 61  VAL H CA  1 
ATOM   22677 C C   . VAL H 1 61  ? 10.794  -30.554 55.628  1.00 29.75  ? 61  VAL H C   1 
ATOM   22678 O O   . VAL H 1 61  ? 11.734  -31.287 55.964  1.00 27.44  ? 61  VAL H O   1 
ATOM   22679 C CB  . VAL H 1 61  ? 8.434   -31.038 56.437  1.00 26.25  ? 61  VAL H CB  1 
ATOM   22680 C CG1 . VAL H 1 61  ? 8.803   -32.471 56.121  1.00 26.14  ? 61  VAL H CG1 1 
ATOM   22681 C CG2 . VAL H 1 61  ? 7.511   -30.950 57.678  1.00 26.92  ? 61  VAL H CG2 1 
ATOM   22682 N N   . ALA H 1 62  ? 10.699  -30.055 54.393  1.00 31.63  ? 62  ALA H N   1 
ATOM   22683 C CA  . ALA H 1 62  ? 11.776  -30.247 53.425  1.00 32.77  ? 62  ALA H CA  1 
ATOM   22684 C C   . ALA H 1 62  ? 13.113  -29.720 53.956  1.00 32.33  ? 62  ALA H C   1 
ATOM   22685 O O   . ALA H 1 62  ? 14.097  -30.463 54.020  1.00 35.30  ? 62  ALA H O   1 
ATOM   22686 C CB  . ALA H 1 62  ? 11.401  -29.575 52.107  1.00 32.24  ? 62  ALA H CB  1 
ATOM   22687 N N   . ASP H 1 63  ? 13.163  -28.442 54.370  1.00 31.58  ? 63  ASP H N   1 
ATOM   22688 C CA  . ASP H 1 63  ? 14.411  -27.871 54.892  1.00 33.83  ? 63  ASP H CA  1 
ATOM   22689 C C   . ASP H 1 63  ? 15.009  -28.755 55.984  1.00 32.74  ? 63  ASP H C   1 
ATOM   22690 O O   . ASP H 1 63  ? 16.224  -28.974 56.030  1.00 32.11  ? 63  ASP H O   1 
ATOM   22691 C CB  . ASP H 1 63  ? 14.197  -26.468 55.485  1.00 33.69  ? 63  ASP H CB  1 
ATOM   22692 C CG  . ASP H 1 63  ? 13.728  -25.409 54.469  1.00 39.46  ? 63  ASP H CG  1 
ATOM   22693 O OD1 . ASP H 1 63  ? 13.701  -25.655 53.230  1.00 33.73  ? 63  ASP H OD1 1 
ATOM   22694 O OD2 . ASP H 1 63  ? 13.369  -24.303 54.963  1.00 31.98  ? 63  ASP H OD2 1 
ATOM   22695 N N   . THR H 1 64  ? 14.168  -29.226 56.914  1.00 32.94  ? 64  THR H N   1 
ATOM   22696 C CA  . THR H 1 64  ? 14.688  -30.024 58.022  1.00 30.28  ? 64  THR H CA  1 
ATOM   22697 C C   . THR H 1 64  ? 15.133  -31.394 57.550  1.00 25.24  ? 64  THR H C   1 
ATOM   22698 O O   . THR H 1 64  ? 16.046  -31.975 58.139  1.00 33.17  ? 64  THR H O   1 
ATOM   22699 C CB  . THR H 1 64  ? 13.647  -30.155 59.139  1.00 31.63  ? 64  THR H CB  1 
ATOM   22700 O OG1 . THR H 1 64  ? 13.141  -28.859 59.462  1.00 27.76  ? 64  THR H OG1 1 
ATOM   22701 C CG2 . THR H 1 64  ? 14.268  -30.770 60.400  1.00 24.19  ? 64  THR H CG2 1 
ATOM   22702 N N   . LEU H 1 65  ? 14.543  -31.898 56.470  1.00 26.46  ? 65  LEU H N   1 
ATOM   22703 C CA  . LEU H 1 65  ? 14.874  -33.218 55.947  1.00 33.49  ? 65  LEU H CA  1 
ATOM   22704 C C   . LEU H 1 65  ? 15.968  -33.199 54.885  1.00 38.04  ? 65  LEU H C   1 
ATOM   22705 O O   . LEU H 1 65  ? 16.492  -34.265 54.552  1.00 41.17  ? 65  LEU H O   1 
ATOM   22706 C CB  . LEU H 1 65  ? 13.625  -33.893 55.357  1.00 31.09  ? 65  LEU H CB  1 
ATOM   22707 C CG  . LEU H 1 65  ? 12.530  -34.314 56.337  1.00 30.81  ? 65  LEU H CG  1 
ATOM   22708 C CD1 . LEU H 1 65  ? 11.394  -35.018 55.613  1.00 27.42  ? 65  LEU H CD1 1 
ATOM   22709 C CD2 . LEU H 1 65  ? 13.134  -35.206 57.409  1.00 31.49  ? 65  LEU H CD2 1 
ATOM   22710 N N   . GLY H 1 66  ? 16.322  -32.032 54.343  1.00 35.42  ? 66  GLY H N   1 
ATOM   22711 C CA  . GLY H 1 66  ? 17.288  -32.002 53.269  1.00 30.82  ? 66  GLY H CA  1 
ATOM   22712 C C   . GLY H 1 66  ? 16.772  -32.523 51.951  1.00 41.96  ? 66  GLY H C   1 
ATOM   22713 O O   . GLY H 1 66  ? 17.571  -32.911 51.094  1.00 50.15  ? 66  GLY H O   1 
ATOM   22714 N N   . ILE H 1 67  ? 15.453  -32.542 51.753  1.00 40.96  ? 67  ILE H N   1 
ATOM   22715 C CA  . ILE H 1 67  ? 14.865  -32.958 50.489  1.00 35.89  ? 67  ILE H CA  1 
ATOM   22716 C C   . ILE H 1 67  ? 14.410  -31.714 49.736  1.00 38.51  ? 67  ILE H C   1 
ATOM   22717 O O   . ILE H 1 67  ? 14.305  -30.622 50.295  1.00 35.83  ? 67  ILE H O   1 
ATOM   22718 C CB  . ILE H 1 67  ? 13.701  -33.966 50.699  1.00 37.52  ? 67  ILE H CB  1 
ATOM   22719 C CG1 . ILE H 1 67  ? 12.622  -33.378 51.611  1.00 34.68  ? 67  ILE H CG1 1 
ATOM   22720 C CG2 . ILE H 1 67  ? 14.220  -35.275 51.289  1.00 30.81  ? 67  ILE H CG2 1 
ATOM   22721 C CD1 . ILE H 1 67  ? 11.230  -33.918 51.373  1.00 31.02  ? 67  ILE H CD1 1 
ATOM   22722 N N   . ASP H 1 68  ? 14.141  -31.882 48.441  1.00 39.73  ? 68  ASP H N   1 
ATOM   22723 C CA  . ASP H 1 68  ? 13.660  -30.812 47.565  1.00 39.83  ? 68  ASP H CA  1 
ATOM   22724 C C   . ASP H 1 68  ? 12.141  -30.688 47.699  1.00 41.88  ? 68  ASP H C   1 
ATOM   22725 O O   . ASP H 1 68  ? 11.377  -31.424 47.061  1.00 38.24  ? 68  ASP H O   1 
ATOM   22726 C CB  . ASP H 1 68  ? 14.085  -31.100 46.126  1.00 44.04  ? 68  ASP H CB  1 
ATOM   22727 C CG  . ASP H 1 68  ? 13.576  -30.065 45.126  1.00 45.38  ? 68  ASP H CG  1 
ATOM   22728 O OD1 . ASP H 1 68  ? 13.273  -28.913 45.519  1.00 43.79  ? 68  ASP H OD1 1 
ATOM   22729 O OD2 . ASP H 1 68  ? 13.485  -30.424 43.930  1.00 46.91  ? 68  ASP H OD2 1 
ATOM   22730 N N   . GLY H 1 69  ? 11.696  -29.731 48.516  1.00 36.64  ? 69  GLY H N   1 
ATOM   22731 C CA  . GLY H 1 69  ? 10.276  -29.589 48.795  1.00 38.44  ? 69  GLY H CA  1 
ATOM   22732 C C   . GLY H 1 69  ? 9.429   -29.250 47.586  1.00 47.09  ? 69  GLY H C   1 
ATOM   22733 O O   . GLY H 1 69  ? 8.206   -29.448 47.618  1.00 48.10  ? 69  GLY H O   1 
ATOM   22734 N N   . THR H 1 70  ? 10.046  -28.723 46.524  1.00 45.94  ? 70  THR H N   1 
ATOM   22735 C CA  . THR H 1 70  ? 9.326   -28.520 45.276  1.00 44.77  ? 70  THR H CA  1 
ATOM   22736 C C   . THR H 1 70  ? 8.919   -29.843 44.646  1.00 38.96  ? 70  THR H C   1 
ATOM   22737 O O   . THR H 1 70  ? 8.009   -29.868 43.814  1.00 42.19  ? 70  THR H O   1 
ATOM   22738 C CB  . THR H 1 70  ? 10.174  -27.693 44.295  1.00 44.96  ? 70  THR H CB  1 
ATOM   22739 O OG1 . THR H 1 70  ? 11.012  -28.555 43.517  1.00 40.51  ? 70  THR H OG1 1 
ATOM   22740 C CG2 . THR H 1 70  ? 11.042  -26.687 45.046  1.00 47.00  ? 70  THR H CG2 1 
ATOM   22741 N N   . SER H 1 71  ? 9.554   -30.938 45.038  1.00 40.16  ? 71  SER H N   1 
ATOM   22742 C CA  . SER H 1 71  ? 9.216   -32.249 44.511  1.00 41.83  ? 71  SER H CA  1 
ATOM   22743 C C   . SER H 1 71  ? 8.065   -32.915 45.253  1.00 42.47  ? 71  SER H C   1 
ATOM   22744 O O   . SER H 1 71  ? 7.562   -33.942 44.787  1.00 42.69  ? 71  SER H O   1 
ATOM   22745 C CB  . SER H 1 71  ? 10.443  -33.157 44.571  1.00 41.56  ? 71  SER H CB  1 
ATOM   22746 O OG  . SER H 1 71  ? 10.750  -33.461 45.923  1.00 44.16  ? 71  SER H OG  1 
ATOM   22747 N N   . VAL H 1 72  ? 7.640   -32.371 46.389  1.00 39.88  ? 72  VAL H N   1 
ATOM   22748 C CA  . VAL H 1 72  ? 6.609   -32.983 47.217  1.00 39.56  ? 72  VAL H CA  1 
ATOM   22749 C C   . VAL H 1 72  ? 5.274   -32.318 46.916  1.00 37.80  ? 72  VAL H C   1 
ATOM   22750 O O   . VAL H 1 72  ? 5.151   -31.088 46.970  1.00 39.56  ? 72  VAL H O   1 
ATOM   22751 C CB  . VAL H 1 72  ? 6.967   -32.870 48.707  1.00 41.30  ? 72  VAL H CB  1 
ATOM   22752 C CG1 . VAL H 1 72  ? 5.900   -33.556 49.580  1.00 40.46  ? 72  VAL H CG1 1 
ATOM   22753 C CG2 . VAL H 1 72  ? 8.345   -33.454 48.938  1.00 39.97  ? 72  VAL H CG2 1 
ATOM   22754 N N   . HIS H 1 73  ? 4.276   -33.124 46.602  1.00 37.04  ? 73  HIS H N   1 
ATOM   22755 C CA  . HIS H 1 73  ? 2.985   -32.621 46.154  1.00 38.75  ? 73  HIS H CA  1 
ATOM   22756 C C   . HIS H 1 73  ? 1.927   -32.971 47.191  1.00 37.14  ? 73  HIS H C   1 
ATOM   22757 O O   . HIS H 1 73  ? 1.648   -34.148 47.427  1.00 38.69  ? 73  HIS H O   1 
ATOM   22758 C CB  . HIS H 1 73  ? 2.636   -33.195 44.789  1.00 36.56  ? 73  HIS H CB  1 
ATOM   22759 C CG  . HIS H 1 73  ? 3.705   -32.988 43.761  1.00 46.01  ? 73  HIS H CG  1 
ATOM   22760 N ND1 . HIS H 1 73  ? 4.917   -33.646 43.796  1.00 44.49  ? 73  HIS H ND1 1 
ATOM   22761 C CD2 . HIS H 1 73  ? 3.754   -32.168 42.684  1.00 48.63  ? 73  HIS H CD2 1 
ATOM   22762 C CE1 . HIS H 1 73  ? 5.654   -33.263 42.767  1.00 47.41  ? 73  HIS H CE1 1 
ATOM   22763 N NE2 . HIS H 1 73  ? 4.972   -32.365 42.079  1.00 57.47  ? 73  HIS H NE2 1 
ATOM   22764 N N   . VAL H 1 74  ? 1.358   -31.954 47.816  1.00 31.13  ? 74  VAL H N   1 
ATOM   22765 C CA  . VAL H 1 74  ? 0.228   -32.157 48.711  1.00 32.80  ? 74  VAL H CA  1 
ATOM   22766 C C   . VAL H 1 74  ? -1.036  -32.194 47.872  1.00 39.83  ? 74  VAL H C   1 
ATOM   22767 O O   . VAL H 1 74  ? -1.236  -31.354 46.985  1.00 45.49  ? 74  VAL H O   1 
ATOM   22768 C CB  . VAL H 1 74  ? 0.164   -31.052 49.774  1.00 33.14  ? 74  VAL H CB  1 
ATOM   22769 C CG1 . VAL H 1 74  ? -1.155  -31.117 50.556  1.00 31.48  ? 74  VAL H CG1 1 
ATOM   22770 C CG2 . VAL H 1 74  ? 1.351   -31.185 50.699  1.00 35.42  ? 74  VAL H CG2 1 
ATOM   22771 N N   . GLU H 1 75  ? -1.875  -33.184 48.129  1.00 33.94  ? 75  GLU H N   1 
ATOM   22772 C CA  . GLU H 1 75  ? -3.119  -33.382 47.406  1.00 37.44  ? 75  GLU H CA  1 
ATOM   22773 C C   . GLU H 1 75  ? -4.236  -33.213 48.421  1.00 40.11  ? 75  GLU H C   1 
ATOM   22774 O O   . GLU H 1 75  ? -4.377  -34.025 49.340  1.00 43.61  ? 75  GLU H O   1 
ATOM   22775 C CB  . GLU H 1 75  ? -3.154  -34.757 46.751  1.00 42.78  ? 75  GLU H CB  1 
ATOM   22776 C CG  . GLU H 1 75  ? -4.045  -34.839 45.547  1.00 48.01  ? 75  GLU H CG  1 
ATOM   22777 C CD  . GLU H 1 75  ? -3.608  -33.903 44.433  1.00 50.05  ? 75  GLU H CD  1 
ATOM   22778 O OE1 . GLU H 1 75  ? -2.386  -33.777 44.189  1.00 50.39  ? 75  GLU H OE1 1 
ATOM   22779 O OE2 . GLU H 1 75  ? -4.494  -33.301 43.794  1.00 52.66  ? 75  GLU H OE2 1 
ATOM   22780 N N   . ARG H 1 76  ? -4.989  -32.139 48.295  1.00 42.16  ? 76  ARG H N   1 
ATOM   22781 C CA  . ARG H 1 76  ? -6.068  -31.894 49.229  1.00 43.61  ? 76  ARG H CA  1 
ATOM   22782 C C   . ARG H 1 76  ? -7.300  -32.657 48.770  1.00 47.89  ? 76  ARG H C   1 
ATOM   22783 O O   . ARG H 1 76  ? -7.627  -32.672 47.579  1.00 49.08  ? 76  ARG H O   1 
ATOM   22784 C CB  . ARG H 1 76  ? -6.362  -30.393 49.339  1.00 51.20  ? 76  ARG H CB  1 
ATOM   22785 C CG  . ARG H 1 76  ? -5.531  -29.644 50.384  1.00 49.32  ? 76  ARG H CG  1 
ATOM   22786 C CD  . ARG H 1 76  ? -5.058  -28.282 49.914  1.00 50.55  ? 76  ARG H CD  1 
ATOM   22787 N NE  . ARG H 1 76  ? -3.907  -28.412 49.023  1.00 54.47  ? 76  ARG H NE  1 
ATOM   22788 C CZ  . ARG H 1 76  ? -2.638  -28.236 49.373  1.00 51.48  ? 76  ARG H CZ  1 
ATOM   22789 N NH1 . ARG H 1 76  ? -2.298  -27.875 50.605  1.00 47.13  ? 76  ARG H NH1 1 
ATOM   22790 N NH2 . ARG H 1 76  ? -1.686  -28.414 48.460  1.00 47.27  ? 76  ARG H NH2 1 
ATOM   22791 N N   . THR H 1 77  ? -7.923  -33.367 49.698  1.00 43.80  ? 77  THR H N   1 
ATOM   22792 C CA  . THR H 1 77  ? -9.343  -33.656 49.640  1.00 45.55  ? 77  THR H CA  1 
ATOM   22793 C C   . THR H 1 77  ? -9.993  -32.829 50.737  1.00 46.54  ? 77  THR H C   1 
ATOM   22794 O O   . THR H 1 77  ? -9.315  -32.247 51.585  1.00 56.09  ? 77  THR H O   1 
ATOM   22795 C CB  . THR H 1 77  ? -9.632  -35.161 49.810  1.00 48.06  ? 77  THR H CB  1 
ATOM   22796 O OG1 . THR H 1 77  ? -9.539  -35.545 51.192  1.00 40.30  ? 77  THR H OG1 1 
ATOM   22797 C CG2 . THR H 1 77  ? -8.654  -36.002 48.992  1.00 43.37  ? 77  THR H CG2 1 
ATOM   22798 N N   . GLN H 1 78  ? -11.306 -32.738 50.720  1.00 46.21  ? 78  GLN H N   1 
ATOM   22799 C CA  . GLN H 1 78  ? -11.990 -32.077 51.822  1.00 43.53  ? 78  GLN H CA  1 
ATOM   22800 C C   . GLN H 1 78  ? -12.942 -33.055 52.493  1.00 49.55  ? 78  GLN H C   1 
ATOM   22801 O O   . GLN H 1 78  ? -13.963 -32.665 53.063  1.00 53.04  ? 78  GLN H O   1 
ATOM   22802 C CB  . GLN H 1 78  ? -12.709 -30.816 51.347  1.00 46.10  ? 78  GLN H CB  1 
ATOM   22803 C CG  . GLN H 1 78  ? -11.918 -30.044 50.286  1.00 55.94  ? 78  GLN H CG  1 
ATOM   22804 C CD  . GLN H 1 78  ? -11.511 -28.638 50.717  1.00 62.64  ? 78  GLN H CD  1 
ATOM   22805 O OE1 . GLN H 1 78  ? -11.827 -28.187 51.826  1.00 65.37  ? 78  GLN H OE1 1 
ATOM   22806 N NE2 . GLN H 1 78  ? -10.780 -27.946 49.843  1.00 46.04  ? 78  GLN H NE2 1 
ATOM   22807 N N   . THR H 1 79  ? -12.601 -34.339 52.413  1.00 48.95  ? 79  THR H N   1 
ATOM   22808 C CA  . THR H 1 79  ? -13.335 -35.438 53.016  1.00 46.90  ? 79  THR H CA  1 
ATOM   22809 C C   . THR H 1 79  ? -12.329 -36.436 53.581  1.00 43.77  ? 79  THR H C   1 
ATOM   22810 O O   . THR H 1 79  ? -11.255 -36.626 53.001  1.00 41.27  ? 79  THR H O   1 
ATOM   22811 C CB  . THR H 1 79  ? -14.231 -36.163 52.001  1.00 42.06  ? 79  THR H CB  1 
ATOM   22812 O OG1 . THR H 1 79  ? -13.414 -36.662 50.941  1.00 49.08  ? 79  THR H OG1 1 
ATOM   22813 C CG2 . THR H 1 79  ? -15.267 -35.221 51.418  1.00 47.42  ? 79  THR H CG2 1 
ATOM   22814 N N   . PRO H 1 80  ? -12.668 -37.077 54.698  1.00 39.38  ? 80  PRO H N   1 
ATOM   22815 C CA  . PRO H 1 80  ? -11.830 -38.178 55.199  1.00 40.71  ? 80  PRO H CA  1 
ATOM   22816 C C   . PRO H 1 80  ? -11.635 -39.250 54.137  1.00 38.85  ? 80  PRO H C   1 
ATOM   22817 O O   . PRO H 1 80  ? -12.544 -39.552 53.365  1.00 37.02  ? 80  PRO H O   1 
ATOM   22818 C CB  . PRO H 1 80  ? -12.636 -38.710 56.388  1.00 35.94  ? 80  PRO H CB  1 
ATOM   22819 C CG  . PRO H 1 80  ? -13.445 -37.527 56.836  1.00 34.23  ? 80  PRO H CG  1 
ATOM   22820 C CD  . PRO H 1 80  ? -13.820 -36.821 55.572  1.00 41.18  ? 80  PRO H CD  1 
ATOM   22821 N N   . LEU H 1 81  ? -10.439 -39.839 54.111  1.00 35.24  ? 81  LEU H N   1 
ATOM   22822 C CA  . LEU H 1 81  ? -10.073 -40.774 53.048  1.00 36.23  ? 81  LEU H CA  1 
ATOM   22823 C C   . LEU H 1 81  ? -10.748 -42.132 53.269  1.00 30.52  ? 81  LEU H C   1 
ATOM   22824 O O   . LEU H 1 81  ? -10.108 -43.159 53.488  1.00 35.20  ? 81  LEU H O   1 
ATOM   22825 C CB  . LEU H 1 81  ? -8.557  -40.897 52.959  1.00 32.10  ? 81  LEU H CB  1 
ATOM   22826 C CG  . LEU H 1 81  ? -7.857  -39.535 52.845  1.00 35.31  ? 81  LEU H CG  1 
ATOM   22827 C CD1 . LEU H 1 81  ? -6.345  -39.684 52.919  1.00 36.12  ? 81  LEU H CD1 1 
ATOM   22828 C CD2 . LEU H 1 81  ? -8.252  -38.804 51.576  1.00 33.96  ? 81  LEU H CD2 1 
ATOM   22829 N N   . SER H 1 82  ? -12.079 -42.103 53.200  1.00 31.11  ? 82  SER H N   1 
ATOM   22830 C CA  . SER H 1 82  ? -12.927 -43.279 53.315  1.00 34.59  ? 82  SER H CA  1 
ATOM   22831 C C   . SER H 1 82  ? -12.714 -44.221 52.135  1.00 33.77  ? 82  SER H C   1 
ATOM   22832 O O   . SER H 1 82  ? -12.166 -43.848 51.091  1.00 30.81  ? 82  SER H O   1 
ATOM   22833 C CB  . SER H 1 82  ? -14.394 -42.878 53.317  1.00 31.76  ? 82  SER H CB  1 
ATOM   22834 O OG  . SER H 1 82  ? -14.690 -42.330 52.040  1.00 35.77  ? 82  SER H OG  1 
ATOM   22835 N N   . GLU H 1 83  ? -13.203 -45.450 52.293  1.00 27.74  ? 83  GLU H N   1 
ATOM   22836 C CA  . GLU H 1 83  ? -13.177 -46.387 51.174  1.00 32.96  ? 83  GLU H CA  1 
ATOM   22837 C C   . GLU H 1 83  ? -13.768 -45.757 49.915  1.00 33.51  ? 83  GLU H C   1 
ATOM   22838 O O   . GLU H 1 83  ? -13.175 -45.832 48.832  1.00 31.50  ? 83  GLU H O   1 
ATOM   22839 C CB  . GLU H 1 83  ? -13.923 -47.668 51.542  1.00 30.08  ? 83  GLU H CB  1 
ATOM   22840 C CG  . GLU H 1 83  ? -13.233 -48.507 52.622  1.00 30.79  ? 83  GLU H CG  1 
ATOM   22841 C CD  . GLU H 1 83  ? -11.877 -49.048 52.189  1.00 26.19  ? 83  GLU H CD  1 
ATOM   22842 O OE1 . GLU H 1 83  ? -10.859 -48.348 52.389  1.00 27.33  ? 83  GLU H OE1 1 
ATOM   22843 O OE2 . GLU H 1 83  ? -11.830 -50.179 51.662  1.00 28.33  ? 83  GLU H OE2 1 
ATOM   22844 N N   . ALA H 1 84  ? -14.924 -45.101 50.050  1.00 34.63  ? 84  ALA H N   1 
ATOM   22845 C CA  . ALA H 1 84  ? -15.590 -44.511 48.890  1.00 34.27  ? 84  ALA H CA  1 
ATOM   22846 C C   . ALA H 1 84  ? -14.671 -43.544 48.152  1.00 33.01  ? 84  ALA H C   1 
ATOM   22847 O O   . ALA H 1 84  ? -14.601 -43.556 46.914  1.00 31.45  ? 84  ALA H O   1 
ATOM   22848 C CB  . ALA H 1 84  ? -16.872 -43.806 49.334  1.00 36.27  ? 84  ALA H CB  1 
ATOM   22849 N N   . VAL H 1 85  ? -13.941 -42.713 48.894  1.00 31.99  ? 85  VAL H N   1 
ATOM   22850 C CA  . VAL H 1 85  ? -13.007 -41.793 48.256  1.00 35.23  ? 85  VAL H CA  1 
ATOM   22851 C C   . VAL H 1 85  ? -11.944 -42.549 47.459  1.00 33.07  ? 85  VAL H C   1 
ATOM   22852 O O   . VAL H 1 85  ? -11.644 -42.191 46.312  1.00 32.28  ? 85  VAL H O   1 
ATOM   22853 C CB  . VAL H 1 85  ? -12.388 -40.856 49.308  1.00 38.04  ? 85  VAL H CB  1 
ATOM   22854 C CG1 . VAL H 1 85  ? -11.226 -40.062 48.706  1.00 30.35  ? 85  VAL H CG1 1 
ATOM   22855 C CG2 . VAL H 1 85  ? -13.469 -39.920 49.846  1.00 35.77  ? 85  VAL H CG2 1 
ATOM   22856 N N   . LEU H 1 86  ? -11.375 -43.622 48.029  1.00 30.45  ? 86  LEU H N   1 
ATOM   22857 C CA  . LEU H 1 86  ? -10.345 -44.365 47.301  1.00 28.59  ? 86  LEU H CA  1 
ATOM   22858 C C   . LEU H 1 86  ? -10.876 -45.034 46.043  1.00 32.34  ? 86  LEU H C   1 
ATOM   22859 O O   . LEU H 1 86  ? -10.079 -45.347 45.148  1.00 35.90  ? 86  LEU H O   1 
ATOM   22860 C CB  . LEU H 1 86  ? -9.688  -45.445 48.169  1.00 30.58  ? 86  LEU H CB  1 
ATOM   22861 C CG  . LEU H 1 86  ? -9.232  -45.144 49.596  1.00 32.89  ? 86  LEU H CG  1 
ATOM   22862 C CD1 . LEU H 1 86  ? -8.346  -46.294 50.088  1.00 28.66  ? 86  LEU H CD1 1 
ATOM   22863 C CD2 . LEU H 1 86  ? -8.495  -43.832 49.656  1.00 27.25  ? 86  LEU H CD2 1 
ATOM   22864 N N   . GLN H 1 87  ? -12.185 -45.289 45.957  1.00 26.92  ? 87  GLN H N   1 
ATOM   22865 C CA  . GLN H 1 87  ? -12.766 -45.828 44.731  1.00 31.47  ? 87  GLN H CA  1 
ATOM   22866 C C   . GLN H 1 87  ? -13.249 -44.747 43.766  1.00 34.13  ? 87  GLN H C   1 
ATOM   22867 O O   . GLN H 1 87  ? -13.532 -45.066 42.608  1.00 36.79  ? 87  GLN H O   1 
ATOM   22868 C CB  . GLN H 1 87  ? -13.930 -46.778 45.062  1.00 34.03  ? 87  GLN H CB  1 
ATOM   22869 C CG  . GLN H 1 87  ? -13.512 -47.986 45.915  1.00 37.45  ? 87  GLN H CG  1 
ATOM   22870 C CD  . GLN H 1 87  ? -14.671 -48.924 46.278  1.00 37.27  ? 87  GLN H CD  1 
ATOM   22871 O OE1 . GLN H 1 87  ? -15.267 -48.804 47.342  1.00 38.79  ? 87  GLN H OE1 1 
ATOM   22872 N NE2 . GLN H 1 87  ? -14.969 -49.872 45.399  1.00 36.21  ? 87  GLN H NE2 1 
ATOM   22873 N N   . ASP H 1 88  ? -13.339 -43.490 44.202  1.00 34.62  ? 88  ASP H N   1 
ATOM   22874 C CA  . ASP H 1 88  ? -13.937 -42.431 43.392  1.00 35.97  ? 88  ASP H CA  1 
ATOM   22875 C C   . ASP H 1 88  ? -13.145 -42.212 42.109  1.00 39.86  ? 88  ASP H C   1 
ATOM   22876 O O   . ASP H 1 88  ? -11.941 -41.921 42.177  1.00 34.37  ? 88  ASP H O   1 
ATOM   22877 C CB  . ASP H 1 88  ? -14.020 -41.119 44.177  1.00 38.28  ? 88  ASP H CB  1 
ATOM   22878 C CG  . ASP H 1 88  ? -14.679 -39.975 43.366  1.00 46.05  ? 88  ASP H CG  1 
ATOM   22879 O OD1 . ASP H 1 88  ? -14.132 -39.541 42.319  1.00 44.60  ? 88  ASP H OD1 1 
ATOM   22880 O OD2 . ASP H 1 88  ? -15.751 -39.499 43.781  1.00 45.00  ? 88  ASP H OD2 1 
ATOM   22881 N N   . PRO H 1 89  ? -13.774 -42.329 40.932  1.00 40.20  ? 89  PRO H N   1 
ATOM   22882 C CA  . PRO H 1 89  ? -13.061 -42.029 39.677  1.00 44.03  ? 89  PRO H CA  1 
ATOM   22883 C C   . PRO H 1 89  ? -12.287 -40.712 39.670  1.00 43.50  ? 89  PRO H C   1 
ATOM   22884 O O   . PRO H 1 89  ? -11.159 -40.695 39.164  1.00 42.10  ? 89  PRO H O   1 
ATOM   22885 C CB  . PRO H 1 89  ? -14.195 -42.035 38.641  1.00 40.99  ? 89  PRO H CB  1 
ATOM   22886 C CG  . PRO H 1 89  ? -15.163 -43.031 39.165  1.00 40.43  ? 89  PRO H CG  1 
ATOM   22887 C CD  . PRO H 1 89  ? -15.052 -43.019 40.687  1.00 37.76  ? 89  PRO H CD  1 
ATOM   22888 N N   . GLU H 1 90  ? -12.831 -39.619 40.224  1.00 43.31  ? 90  GLU H N   1 
ATOM   22889 C CA  . GLU H 1 90  ? -12.124 -38.340 40.141  1.00 44.96  ? 90  GLU H CA  1 
ATOM   22890 C C   . GLU H 1 90  ? -10.894 -38.318 41.040  1.00 45.80  ? 90  GLU H C   1 
ATOM   22891 O O   . GLU H 1 90  ? -9.872  -37.715 40.690  1.00 46.69  ? 90  GLU H O   1 
ATOM   22892 C CB  . GLU H 1 90  ? -13.043 -37.180 40.514  1.00 51.88  ? 90  GLU H CB  1 
ATOM   22893 C CG  . GLU H 1 90  ? -12.251 -35.970 40.991  1.00 56.11  ? 90  GLU H CG  1 
ATOM   22894 C CD  . GLU H 1 90  ? -13.113 -34.854 41.508  1.00 65.91  ? 90  GLU H CD  1 
ATOM   22895 O OE1 . GLU H 1 90  ? -13.935 -35.107 42.418  1.00 69.71  ? 90  GLU H OE1 1 
ATOM   22896 O OE2 . GLU H 1 90  ? -12.945 -33.716 41.018  1.00 69.52  ? 90  GLU H OE2 1 
ATOM   22897 N N   . PHE H 1 91  ? -10.989 -38.938 42.215  1.00 45.42  ? 91  PHE H N   1 
ATOM   22898 C CA  . PHE H 1 91  ? -9.828  -39.080 43.082  1.00 42.44  ? 91  PHE H CA  1 
ATOM   22899 C C   . PHE H 1 91  ? -8.714  -39.845 42.378  1.00 41.26  ? 91  PHE H C   1 
ATOM   22900 O O   . PHE H 1 91  ? -7.533  -39.490 42.488  1.00 37.63  ? 91  PHE H O   1 
ATOM   22901 C CB  . PHE H 1 91  ? -10.245 -39.787 44.374  1.00 38.34  ? 91  PHE H CB  1 
ATOM   22902 C CG  . PHE H 1 91  ? -9.118  -40.021 45.333  1.00 33.62  ? 91  PHE H CG  1 
ATOM   22903 C CD1 . PHE H 1 91  ? -8.685  -39.010 46.174  1.00 34.62  ? 91  PHE H CD1 1 
ATOM   22904 C CD2 . PHE H 1 91  ? -8.495  -41.249 45.393  1.00 30.52  ? 91  PHE H CD2 1 
ATOM   22905 C CE1 . PHE H 1 91  ? -7.650  -39.222 47.058  1.00 32.21  ? 91  PHE H CE1 1 
ATOM   22906 C CE2 . PHE H 1 91  ? -7.465  -41.469 46.281  1.00 33.99  ? 91  PHE H CE2 1 
ATOM   22907 C CZ  . PHE H 1 91  ? -7.041  -40.448 47.116  1.00 33.35  ? 91  PHE H CZ  1 
ATOM   22908 N N   . ILE H 1 92  ? -9.077  -40.896 41.642  1.00 38.71  ? 92  ILE H N   1 
ATOM   22909 C CA  . ILE H 1 92  ? -8.078  -41.721 40.982  1.00 41.15  ? 92  ILE H CA  1 
ATOM   22910 C C   . ILE H 1 92  ? -7.419  -40.955 39.853  1.00 42.63  ? 92  ILE H C   1 
ATOM   22911 O O   . ILE H 1 92  ? -6.222  -41.114 39.602  1.00 42.18  ? 92  ILE H O   1 
ATOM   22912 C CB  . ILE H 1 92  ? -8.715  -43.026 40.482  1.00 39.33  ? 92  ILE H CB  1 
ATOM   22913 C CG1 . ILE H 1 92  ? -9.357  -43.768 41.654  1.00 37.25  ? 92  ILE H CG1 1 
ATOM   22914 C CG2 . ILE H 1 92  ? -7.679  -43.891 39.794  1.00 31.31  ? 92  ILE H CG2 1 
ATOM   22915 C CD1 . ILE H 1 92  ? -10.207 -44.935 41.237  1.00 33.65  ? 92  ILE H CD1 1 
ATOM   22916 N N   . ASP H 1 93  ? -8.174  -40.112 39.156  1.00 43.07  ? 93  ASP H N   1 
ATOM   22917 C CA  . ASP H 1 93  ? -7.553  -39.264 38.152  1.00 41.46  ? 93  ASP H CA  1 
ATOM   22918 C C   . ASP H 1 93  ? -6.540  -38.331 38.800  1.00 42.54  ? 93  ASP H C   1 
ATOM   22919 O O   . ASP H 1 93  ? -5.407  -38.201 38.322  1.00 42.03  ? 93  ASP H O   1 
ATOM   22920 C CB  . ASP H 1 93  ? -8.629  -38.487 37.393  1.00 46.77  ? 93  ASP H CB  1 
ATOM   22921 C CG  . ASP H 1 93  ? -9.481  -39.396 36.518  1.00 54.14  ? 93  ASP H CG  1 
ATOM   22922 O OD1 . ASP H 1 93  ? -10.709 -39.165 36.414  1.00 57.37  ? 93  ASP H OD1 1 
ATOM   22923 O OD2 . ASP H 1 93  ? -8.915  -40.360 35.947  1.00 56.52  ? 93  ASP H OD2 1 
ATOM   22924 N N   . ARG H 1 94  ? -6.921  -37.710 39.924  1.00 41.34  ? 94  ARG H N   1 
ATOM   22925 C CA  . ARG H 1 94  ? -6.024  -36.789 40.612  1.00 38.99  ? 94  ARG H CA  1 
ATOM   22926 C C   . ARG H 1 94  ? -4.674  -37.441 40.891  1.00 39.73  ? 94  ARG H C   1 
ATOM   22927 O O   . ARG H 1 94  ? -3.620  -36.862 40.608  1.00 41.16  ? 94  ARG H O   1 
ATOM   22928 C CB  . ARG H 1 94  ? -6.677  -36.297 41.906  1.00 41.03  ? 94  ARG H CB  1 
ATOM   22929 C CG  . ARG H 1 94  ? -8.052  -35.678 41.703  1.00 46.16  ? 94  ARG H CG  1 
ATOM   22930 C CD  . ARG H 1 94  ? -8.087  -34.235 42.118  1.00 55.29  ? 94  ARG H CD  1 
ATOM   22931 N NE  . ARG H 1 94  ? -7.752  -34.080 43.528  1.00 64.89  ? 94  ARG H NE  1 
ATOM   22932 C CZ  . ARG H 1 94  ? -8.572  -34.343 44.535  1.00 58.11  ? 94  ARG H CZ  1 
ATOM   22933 N NH1 . ARG H 1 94  ? -9.834  -34.685 44.329  1.00 60.74  ? 94  ARG H NH1 1 
ATOM   22934 N NH2 . ARG H 1 94  ? -8.116  -34.251 45.780  1.00 54.93  ? 94  ARG H NH2 1 
ATOM   22935 N N   . LEU H 1 95  ? -4.685  -38.669 41.416  1.00 40.33  ? 95  LEU H N   1 
ATOM   22936 C CA  . LEU H 1 95  ? -3.423  -39.349 41.685  1.00 39.29  ? 95  LEU H CA  1 
ATOM   22937 C C   . LEU H 1 95  ? -2.746  -39.783 40.396  1.00 39.81  ? 95  LEU H C   1 
ATOM   22938 O O   . LEU H 1 95  ? -1.513  -39.761 40.305  1.00 35.35  ? 95  LEU H O   1 
ATOM   22939 C CB  . LEU H 1 95  ? -3.639  -40.563 42.589  1.00 36.32  ? 95  LEU H CB  1 
ATOM   22940 C CG  . LEU H 1 95  ? -4.191  -40.262 43.968  1.00 35.46  ? 95  LEU H CG  1 
ATOM   22941 C CD1 . LEU H 1 95  ? -4.354  -41.550 44.759  1.00 32.64  ? 95  LEU H CD1 1 
ATOM   22942 C CD2 . LEU H 1 95  ? -3.312  -39.251 44.696  1.00 37.49  ? 95  LEU H CD2 1 
ATOM   22943 N N   . ALA H 1 96  ? -3.534  -40.205 39.398  1.00 35.52  ? 96  ALA H N   1 
ATOM   22944 C CA  . ALA H 1 96  ? -2.946  -40.688 38.152  1.00 39.63  ? 96  ALA H CA  1 
ATOM   22945 C C   . ALA H 1 96  ? -2.093  -39.615 37.485  1.00 43.60  ? 96  ALA H C   1 
ATOM   22946 O O   . ALA H 1 96  ? -1.096  -39.937 36.829  1.00 47.61  ? 96  ALA H O   1 
ATOM   22947 C CB  . ALA H 1 96  ? -4.038  -41.173 37.199  1.00 36.36  ? 96  ALA H CB  1 
ATOM   22948 N N   . ALA H 1 97  ? -2.458  -38.337 37.660  1.00 42.52  ? 97  ALA H N   1 
ATOM   22949 C CA  . ALA H 1 97  ? -1.677  -37.230 37.114  1.00 40.81  ? 97  ALA H CA  1 
ATOM   22950 C C   . ALA H 1 97  ? -0.236  -37.224 37.610  1.00 42.82  ? 97  ALA H C   1 
ATOM   22951 O O   . ALA H 1 97  ? 0.644   -36.706 36.915  1.00 50.16  ? 97  ALA H O   1 
ATOM   22952 C CB  . ALA H 1 97  ? -2.338  -35.898 37.470  1.00 40.06  ? 97  ALA H CB  1 
ATOM   22953 N N   . HIS H 1 98  ? 0.025   -37.784 38.790  1.00 39.96  ? 98  HIS H N   1 
ATOM   22954 C CA  . HIS H 1 98  ? 1.368   -37.817 39.353  1.00 37.72  ? 98  HIS H CA  1 
ATOM   22955 C C   . HIS H 1 98  ? 2.127   -39.081 38.967  1.00 42.74  ? 98  HIS H C   1 
ATOM   22956 O O   . HIS H 1 98  ? 3.330   -39.022 38.697  1.00 47.11  ? 98  HIS H O   1 
ATOM   22957 C CB  . HIS H 1 98  ? 1.302   -37.718 40.884  1.00 41.50  ? 98  HIS H CB  1 
ATOM   22958 C CG  . HIS H 1 98  ? 0.627   -36.482 41.393  1.00 41.44  ? 98  HIS H CG  1 
ATOM   22959 N ND1 . HIS H 1 98  ? 1.271   -35.268 41.501  1.00 40.85  ? 98  HIS H ND1 1 
ATOM   22960 C CD2 . HIS H 1 98  ? -0.640  -36.274 41.828  1.00 42.43  ? 98  HIS H CD2 1 
ATOM   22961 C CE1 . HIS H 1 98  ? 0.431   -34.366 41.979  1.00 42.78  ? 98  HIS H CE1 1 
ATOM   22962 N NE2 . HIS H 1 98  ? -0.733  -34.953 42.194  1.00 41.35  ? 98  HIS H NE2 1 
ATOM   22963 N N   . THR H 1 99  ? 1.451   -40.230 38.945  1.00 45.92  ? 99  THR H N   1 
ATOM   22964 C CA  . THR H 1 99  ? 2.143   -41.505 38.771  1.00 45.83  ? 99  THR H CA  1 
ATOM   22965 C C   . THR H 1 99  ? 2.442   -41.816 37.311  1.00 48.38  ? 99  THR H C   1 
ATOM   22966 O O   . THR H 1 99  ? 3.450   -42.473 37.014  1.00 52.54  ? 99  THR H O   1 
ATOM   22967 C CB  . THR H 1 99  ? 1.309   -42.626 39.373  1.00 42.58  ? 99  THR H CB  1 
ATOM   22968 O OG1 . THR H 1 99  ? 0.039   -42.660 38.711  1.00 40.79  ? 99  THR H OG1 1 
ATOM   22969 C CG2 . THR H 1 99  ? 1.100   -42.387 40.875  1.00 43.98  ? 99  THR H CG2 1 
ATOM   22970 N N   . GLY H 1 100 ? 1.586   -41.360 36.400  1.00 49.55  ? 100 GLY H N   1 
ATOM   22971 C CA  . GLY H 1 100 ? 1.778   -41.561 34.976  1.00 52.82  ? 100 GLY H CA  1 
ATOM   22972 C C   . GLY H 1 100 ? 1.362   -42.945 34.536  1.00 50.12  ? 100 GLY H C   1 
ATOM   22973 O O   . GLY H 1 100 ? 0.198   -43.328 34.691  1.00 54.46  ? 100 GLY H O   1 
ATOM   22974 N N   . THR H 1 101 ? 2.302   -43.702 33.969  1.00 54.09  ? 101 THR H N   1 
ATOM   22975 C CA  . THR H 1 101 ? 2.068   -45.130 33.781  1.00 57.82  ? 101 THR H CA  1 
ATOM   22976 C C   . THR H 1 101 ? 1.965   -45.844 35.125  1.00 56.07  ? 101 THR H C   1 
ATOM   22977 O O   . THR H 1 101 ? 1.266   -46.860 35.237  1.00 54.21  ? 101 THR H O   1 
ATOM   22978 C CB  . THR H 1 101 ? 3.184   -45.750 32.925  1.00 59.40  ? 101 THR H CB  1 
ATOM   22979 O OG1 . THR H 1 101 ? 4.358   -45.954 33.727  1.00 58.71  ? 101 THR H OG1 1 
ATOM   22980 C CG2 . THR H 1 101 ? 3.534   -44.847 31.727  1.00 53.28  ? 101 THR H CG2 1 
ATOM   22981 N N   . GLY H 1 102 ? 2.630   -45.308 36.155  1.00 52.42  ? 102 GLY H N   1 
ATOM   22982 C CA  . GLY H 1 102 ? 2.724   -45.934 37.456  1.00 48.43  ? 102 GLY H CA  1 
ATOM   22983 C C   . GLY H 1 102 ? 4.048   -46.613 37.737  1.00 51.55  ? 102 GLY H C   1 
ATOM   22984 O O   . GLY H 1 102 ? 4.217   -47.185 38.824  1.00 44.96  ? 102 GLY H O   1 
ATOM   22985 N N   . ALA H 1 103 ? 4.992   -46.566 36.801  1.00 48.06  ? 103 ALA H N   1 
ATOM   22986 C CA  . ALA H 1 103 ? 6.266   -47.248 36.989  1.00 52.43  ? 103 ALA H CA  1 
ATOM   22987 C C   . ALA H 1 103 ? 7.113   -46.525 38.029  1.00 45.14  ? 103 ALA H C   1 
ATOM   22988 O O   . ALA H 1 103 ? 7.179   -45.294 38.056  1.00 54.43  ? 103 ALA H O   1 
ATOM   22989 C CB  . ALA H 1 103 ? 7.022   -47.342 35.663  1.00 53.42  ? 103 ALA H CB  1 
ATOM   22990 N N   . GLY H 1 104 ? 7.760   -47.298 38.895  1.00 42.43  ? 104 GLY H N   1 
ATOM   22991 C CA  . GLY H 1 104 ? 8.522   -46.710 39.978  1.00 43.37  ? 104 GLY H CA  1 
ATOM   22992 C C   . GLY H 1 104 ? 7.697   -46.012 41.042  1.00 43.27  ? 104 GLY H C   1 
ATOM   22993 O O   . GLY H 1 104 ? 8.214   -45.141 41.738  1.00 45.45  ? 104 GLY H O   1 
ATOM   22994 N N   . TRP H 1 105 ? 6.430   -46.366 41.194  1.00 37.21  ? 105 TRP H N   1 
ATOM   22995 C CA  . TRP H 1 105 ? 5.571   -45.756 42.196  1.00 39.72  ? 105 TRP H CA  1 
ATOM   22996 C C   . TRP H 1 105 ? 5.030   -46.833 43.129  1.00 38.17  ? 105 TRP H C   1 
ATOM   22997 O O   . TRP H 1 105 ? 5.053   -48.022 42.806  1.00 34.06  ? 105 TRP H O   1 
ATOM   22998 C CB  . TRP H 1 105 ? 4.420   -44.997 41.537  1.00 39.25  ? 105 TRP H CB  1 
ATOM   22999 C CG  . TRP H 1 105 ? 4.765   -43.604 41.126  1.00 40.82  ? 105 TRP H CG  1 
ATOM   23000 C CD1 . TRP H 1 105 ? 5.308   -43.212 39.937  1.00 41.64  ? 105 TRP H CD1 1 
ATOM   23001 C CD2 . TRP H 1 105 ? 4.533   -42.407 41.875  1.00 41.08  ? 105 TRP H CD2 1 
ATOM   23002 N NE1 . TRP H 1 105 ? 5.451   -41.847 39.911  1.00 39.18  ? 105 TRP H NE1 1 
ATOM   23003 C CE2 . TRP H 1 105 ? 4.978   -41.330 41.088  1.00 40.22  ? 105 TRP H CE2 1 
ATOM   23004 C CE3 . TRP H 1 105 ? 4.007   -42.142 43.143  1.00 39.15  ? 105 TRP H CE3 1 
ATOM   23005 C CZ2 . TRP H 1 105 ? 4.918   -40.010 41.528  1.00 42.84  ? 105 TRP H CZ2 1 
ATOM   23006 C CZ3 . TRP H 1 105 ? 3.941   -40.821 43.575  1.00 35.52  ? 105 TRP H CZ3 1 
ATOM   23007 C CH2 . TRP H 1 105 ? 4.399   -39.780 42.774  1.00 39.58  ? 105 TRP H CH2 1 
ATOM   23008 N N   . SER H 1 106 ? 4.565   -46.420 44.308  1.00 37.41  ? 106 SER H N   1 
ATOM   23009 C CA  . SER H 1 106 ? 3.932   -47.373 45.213  1.00 33.31  ? 106 SER H CA  1 
ATOM   23010 C C   . SER H 1 106 ? 2.909   -46.633 46.053  1.00 28.87  ? 106 SER H C   1 
ATOM   23011 O O   . SER H 1 106 ? 2.898   -45.400 46.105  1.00 25.72  ? 106 SER H O   1 
ATOM   23012 C CB  . SER H 1 106 ? 4.942   -48.113 46.110  1.00 26.75  ? 106 SER H CB  1 
ATOM   23013 O OG  . SER H 1 106 ? 5.628   -47.222 46.973  1.00 34.53  ? 106 SER H OG  1 
ATOM   23014 N N   . LEU H 1 107 ? 2.033   -47.401 46.691  1.00 27.69  ? 107 LEU H N   1 
ATOM   23015 C CA  . LEU H 1 107 ? 1.047   -46.857 47.614  1.00 23.72  ? 107 LEU H CA  1 
ATOM   23016 C C   . LEU H 1 107 ? 1.552   -47.113 49.023  1.00 22.92  ? 107 LEU H C   1 
ATOM   23017 O O   . LEU H 1 107 ? 1.965   -48.229 49.338  1.00 24.97  ? 107 LEU H O   1 
ATOM   23018 C CB  . LEU H 1 107 ? -0.326  -47.510 47.408  1.00 25.84  ? 107 LEU H CB  1 
ATOM   23019 C CG  . LEU H 1 107 ? -1.598  -46.737 47.812  1.00 27.38  ? 107 LEU H CG  1 
ATOM   23020 C CD1 . LEU H 1 107 ? -2.850  -47.573 47.674  1.00 26.25  ? 107 LEU H CD1 1 
ATOM   23021 C CD2 . LEU H 1 107 ? -1.552  -46.206 49.210  1.00 29.49  ? 107 LEU H CD2 1 
ATOM   23022 N N   . PHE H 1 108 ? 1.506   -46.084 49.874  1.00 26.67  ? 108 PHE H N   1 
ATOM   23023 C CA  . PHE H 1 108 ? 1.983   -46.151 51.253  1.00 23.11  ? 108 PHE H CA  1 
ATOM   23024 C C   . PHE H 1 108 ? 0.812   -45.826 52.179  1.00 23.75  ? 108 PHE H C   1 
ATOM   23025 O O   . PHE H 1 108 ? 0.746   -44.714 52.730  1.00 20.91  ? 108 PHE H O   1 
ATOM   23026 C CB  . PHE H 1 108 ? 3.148   -45.181 51.447  1.00 23.44  ? 108 PHE H CB  1 
ATOM   23027 C CG  . PHE H 1 108 ? 3.821   -45.262 52.778  1.00 22.85  ? 108 PHE H CG  1 
ATOM   23028 C CD1 . PHE H 1 108 ? 4.614   -46.350 53.108  1.00 30.66  ? 108 PHE H CD1 1 
ATOM   23029 C CD2 . PHE H 1 108 ? 3.708   -44.218 53.688  1.00 23.87  ? 108 PHE H CD2 1 
ATOM   23030 C CE1 . PHE H 1 108 ? 5.261   -46.417 54.344  1.00 27.49  ? 108 PHE H CE1 1 
ATOM   23031 C CE2 . PHE H 1 108 ? 4.352   -44.264 54.915  1.00 24.87  ? 108 PHE H CE2 1 
ATOM   23032 C CZ  . PHE H 1 108 ? 5.130   -45.371 55.250  1.00 26.57  ? 108 PHE H CZ  1 
ATOM   23033 N N   . PRO H 1 109 ? -0.108  -46.777 52.401  1.00 23.52  ? 109 PRO H N   1 
ATOM   23034 C CA  . PRO H 1 109 ? -1.341  -46.480 53.132  1.00 24.97  ? 109 PRO H CA  1 
ATOM   23035 C C   . PRO H 1 109 ? -1.232  -46.796 54.609  1.00 26.49  ? 109 PRO H C   1 
ATOM   23036 O O   . PRO H 1 109 ? -0.540  -47.725 55.035  1.00 26.98  ? 109 PRO H O   1 
ATOM   23037 C CB  . PRO H 1 109 ? -2.358  -47.417 52.470  1.00 20.31  ? 109 PRO H CB  1 
ATOM   23038 C CG  . PRO H 1 109 ? -1.540  -48.633 52.213  1.00 21.33  ? 109 PRO H CG  1 
ATOM   23039 C CD  . PRO H 1 109 ? -0.127  -48.164 51.900  1.00 19.35  ? 109 PRO H CD  1 
ATOM   23040 N N   . CYS H 1 110 ? -1.947  -45.994 55.399  1.00 27.59  ? 110 CYS H N   1 
ATOM   23041 C CA  . CYS H 1 110 ? -1.989  -46.257 56.830  1.00 26.35  ? 110 CYS H CA  1 
ATOM   23042 C C   . CYS H 1 110 ? -2.645  -47.596 57.110  1.00 27.42  ? 110 CYS H C   1 
ATOM   23043 O O   . CYS H 1 110 ? -2.168  -48.370 57.952  1.00 24.19  ? 110 CYS H O   1 
ATOM   23044 C CB  . CYS H 1 110 ? -2.730  -45.145 57.556  1.00 21.38  ? 110 CYS H CB  1 
ATOM   23045 S SG  . CYS H 1 110 ? -2.721  -45.425 59.349  1.00 30.00  ? 110 CYS H SG  1 
ATOM   23046 N N   . VAL H 1 111 ? -3.711  -47.894 56.371  1.00 24.84  ? 111 VAL H N   1 
ATOM   23047 C CA  . VAL H 1 111 ? -4.566  -49.051 56.573  1.00 26.45  ? 111 VAL H CA  1 
ATOM   23048 C C   . VAL H 1 111 ? -4.656  -49.761 55.233  1.00 29.62  ? 111 VAL H C   1 
ATOM   23049 O O   . VAL H 1 111 ? -5.116  -49.163 54.251  1.00 29.06  ? 111 VAL H O   1 
ATOM   23050 C CB  . VAL H 1 111 ? -5.965  -48.626 57.064  1.00 27.81  ? 111 VAL H CB  1 
ATOM   23051 C CG1 . VAL H 1 111 ? -6.803  -49.801 57.432  1.00 29.16  ? 111 VAL H CG1 1 
ATOM   23052 C CG2 . VAL H 1 111 ? -5.860  -47.693 58.255  1.00 30.97  ? 111 VAL H CG2 1 
ATOM   23053 N N   . SER H 1 112 ? -4.207  -51.023 55.174  1.00 25.88  ? 112 SER H N   1 
ATOM   23054 C CA  . SER H 1 112 ? -4.210  -51.759 53.908  1.00 26.29  ? 112 SER H CA  1 
ATOM   23055 C C   . SER H 1 112 ? -5.594  -52.362 53.676  1.00 27.70  ? 112 SER H C   1 
ATOM   23056 O O   . SER H 1 112 ? -5.814  -53.564 53.820  1.00 28.78  ? 112 SER H O   1 
ATOM   23057 C CB  . SER H 1 112 ? -3.140  -52.840 53.891  1.00 26.89  ? 112 SER H CB  1 
ATOM   23058 O OG  . SER H 1 112 ? -1.920  -52.342 53.379  1.00 28.32  ? 112 SER H OG  1 
ATOM   23059 N N   . THR H 1 113 ? -6.531  -51.498 53.294  1.00 25.67  ? 113 THR H N   1 
ATOM   23060 C CA  . THR H 1 113 ? -7.915  -51.906 53.107  1.00 26.37  ? 113 THR H CA  1 
ATOM   23061 C C   . THR H 1 113 ? -8.099  -52.568 51.755  1.00 30.04  ? 113 THR H C   1 
ATOM   23062 O O   . THR H 1 113 ? -7.205  -52.570 50.901  1.00 29.12  ? 113 THR H O   1 
ATOM   23063 C CB  . THR H 1 113 ? -8.872  -50.717 53.184  1.00 26.46  ? 113 THR H CB  1 
ATOM   23064 O OG1 . THR H 1 113 ? -8.479  -49.723 52.227  1.00 27.06  ? 113 THR H OG1 1 
ATOM   23065 C CG2 . THR H 1 113 ? -8.868  -50.103 54.562  1.00 28.76  ? 113 THR H CG2 1 
ATOM   23066 N N   . ARG H 1 114 ? -9.310  -53.096 51.550  1.00 25.22  ? 114 ARG H N   1 
ATOM   23067 C CA  . ARG H 1 114 ? -9.684  -53.589 50.232  1.00 27.14  ? 114 ARG H CA  1 
ATOM   23068 C C   . ARG H 1 114 ? -9.570  -52.483 49.171  1.00 27.73  ? 114 ARG H C   1 
ATOM   23069 O O   . ARG H 1 114 ? -9.011  -52.700 48.093  1.00 23.94  ? 114 ARG H O   1 
ATOM   23070 C CB  . ARG H 1 114 ? -11.098 -54.172 50.298  1.00 26.75  ? 114 ARG H CB  1 
ATOM   23071 C CG  . ARG H 1 114 ? -11.718 -54.532 48.955  1.00 29.36  ? 114 ARG H CG  1 
ATOM   23072 C CD  . ARG H 1 114 ? -13.106 -55.175 49.130  1.00 26.40  ? 114 ARG H CD  1 
ATOM   23073 N NE  . ARG H 1 114 ? -13.742 -55.353 47.836  1.00 31.29  ? 114 ARG H NE  1 
ATOM   23074 C CZ  . ARG H 1 114 ? -13.543 -56.389 47.030  1.00 33.41  ? 114 ARG H CZ  1 
ATOM   23075 N NH1 . ARG H 1 114 ? -12.780 -57.417 47.388  1.00 26.31  ? 114 ARG H NH1 1 
ATOM   23076 N NH2 . ARG H 1 114 ? -14.118 -56.391 45.828  1.00 34.01  ? 114 ARG H NH2 1 
ATOM   23077 N N   . ALA H 1 115 ? -10.093 -51.289 49.459  1.00 25.57  ? 115 ALA H N   1 
ATOM   23078 C CA  . ALA H 1 115 ? -10.037 -50.213 48.469  1.00 27.79  ? 115 ALA H CA  1 
ATOM   23079 C C   . ALA H 1 115 ? -8.611  -49.708 48.249  1.00 29.54  ? 115 ALA H C   1 
ATOM   23080 O O   . ALA H 1 115 ? -8.270  -49.280 47.132  1.00 25.10  ? 115 ALA H O   1 
ATOM   23081 C CB  . ALA H 1 115 ? -10.951 -49.061 48.884  1.00 26.53  ? 115 ALA H CB  1 
ATOM   23082 N N   . ALA H 1 116 ? -7.770  -49.746 49.289  1.00 24.34  ? 116 ALA H N   1 
ATOM   23083 C CA  . ALA H 1 116 ? -6.362  -49.424 49.092  1.00 29.78  ? 116 ALA H CA  1 
ATOM   23084 C C   . ALA H 1 116 ? -5.727  -50.392 48.113  1.00 28.93  ? 116 ALA H C   1 
ATOM   23085 O O   . ALA H 1 116 ? -4.935  -49.986 47.256  1.00 29.06  ? 116 ALA H O   1 
ATOM   23086 C CB  . ALA H 1 116 ? -5.600  -49.440 50.419  1.00 22.43  ? 116 ALA H CB  1 
ATOM   23087 N N   . ALA H 1 117 ? -6.074  -51.681 48.215  1.00 26.07  ? 117 ALA H N   1 
ATOM   23088 C CA  . ALA H 1 117 ? -5.513  -52.656 47.292  1.00 25.52  ? 117 ALA H CA  1 
ATOM   23089 C C   . ALA H 1 117 ? -6.005  -52.403 45.870  1.00 26.26  ? 117 ALA H C   1 
ATOM   23090 O O   . ALA H 1 117 ? -5.204  -52.354 44.928  1.00 28.60  ? 117 ALA H O   1 
ATOM   23091 C CB  . ALA H 1 117 ? -5.846  -54.076 47.757  1.00 27.97  ? 117 ALA H CB  1 
ATOM   23092 N N   . GLN H 1 118 ? -7.316  -52.214 45.698  1.00 25.32  ? 118 GLN H N   1 
ATOM   23093 C CA  . GLN H 1 118 ? -7.855  -51.892 44.373  1.00 31.92  ? 118 GLN H CA  1 
ATOM   23094 C C   . GLN H 1 118 ? -7.184  -50.662 43.777  1.00 30.43  ? 118 GLN H C   1 
ATOM   23095 O O   . GLN H 1 118 ? -6.840  -50.646 42.586  1.00 34.24  ? 118 GLN H O   1 
ATOM   23096 C CB  . GLN H 1 118 ? -9.365  -51.659 44.446  1.00 27.74  ? 118 GLN H CB  1 
ATOM   23097 C CG  . GLN H 1 118 ? -10.204 -52.913 44.545  1.00 25.50  ? 118 GLN H CG  1 
ATOM   23098 C CD  . GLN H 1 118 ? -11.587 -52.611 45.104  1.00 25.47  ? 118 GLN H CD  1 
ATOM   23099 O OE1 . GLN H 1 118 ? -11.769 -51.660 45.856  1.00 27.35  ? 118 GLN H OE1 1 
ATOM   23100 N NE2 . GLN H 1 118 ? -12.563 -53.419 44.734  1.00 30.52  ? 118 GLN H NE2 1 
ATOM   23101 N N   . LEU H 1 119 ? -7.002  -49.618 44.591  1.00 29.33  ? 119 LEU H N   1 
ATOM   23102 C CA  . LEU H 1 119 ? -6.351  -48.396 44.125  1.00 29.12  ? 119 LEU H CA  1 
ATOM   23103 C C   . LEU H 1 119 ? -4.998  -48.683 43.486  1.00 30.89  ? 119 LEU H C   1 
ATOM   23104 O O   . LEU H 1 119 ? -4.643  -48.064 42.478  1.00 33.64  ? 119 LEU H O   1 
ATOM   23105 C CB  . LEU H 1 119 ? -6.200  -47.407 45.289  1.00 28.75  ? 119 LEU H CB  1 
ATOM   23106 C CG  . LEU H 1 119 ? -5.684  -45.982 45.017  1.00 36.77  ? 119 LEU H CG  1 
ATOM   23107 C CD1 . LEU H 1 119 ? -6.368  -45.384 43.787  1.00 35.56  ? 119 LEU H CD1 1 
ATOM   23108 C CD2 . LEU H 1 119 ? -5.862  -45.053 46.257  1.00 26.47  ? 119 LEU H CD2 1 
ATOM   23109 N N   . THR H 1 120 ? -4.219  -49.612 44.058  1.00 26.45  ? 120 THR H N   1 
ATOM   23110 C CA  . THR H 1 120 ? -2.945  -49.951 43.430  1.00 31.48  ? 120 THR H CA  1 
ATOM   23111 C C   . THR H 1 120 ? -3.160  -50.604 42.076  1.00 35.31  ? 120 THR H C   1 
ATOM   23112 O O   . THR H 1 120 ? -2.332  -50.442 41.174  1.00 34.54  ? 120 THR H O   1 
ATOM   23113 C CB  . THR H 1 120 ? -2.118  -50.906 44.295  1.00 31.83  ? 120 THR H CB  1 
ATOM   23114 O OG1 . THR H 1 120 ? -2.765  -52.185 44.339  1.00 27.25  ? 120 THR H OG1 1 
ATOM   23115 C CG2 . THR H 1 120 ? -1.935  -50.373 45.708  1.00 28.68  ? 120 THR H CG2 1 
ATOM   23116 N N   . ARG H 1 121 ? -4.233  -51.385 41.931  1.00 33.88  ? 121 ARG H N   1 
ATOM   23117 C CA  . ARG H 1 121 ? -4.510  -51.987 40.632  1.00 41.99  ? 121 ARG H CA  1 
ATOM   23118 C C   . ARG H 1 121 ? -4.958  -50.929 39.636  1.00 37.01  ? 121 ARG H C   1 
ATOM   23119 O O   . ARG H 1 121 ? -4.483  -50.905 38.498  1.00 38.44  ? 121 ARG H O   1 
ATOM   23120 C CB  . ARG H 1 121 ? -5.562  -53.100 40.761  1.00 42.37  ? 121 ARG H CB  1 
ATOM   23121 C CG  . ARG H 1 121 ? -5.562  -54.112 39.595  1.00 44.17  ? 121 ARG H CG  1 
ATOM   23122 C CD  . ARG H 1 121 ? -6.058  -55.501 40.024  1.00 44.47  ? 121 ARG H CD  1 
ATOM   23123 N NE  . ARG H 1 121 ? -6.594  -56.278 38.909  1.00 53.28  ? 121 ARG H NE  1 
ATOM   23124 C CZ  . ARG H 1 121 ? -7.883  -56.385 38.603  1.00 55.93  ? 121 ARG H CZ  1 
ATOM   23125 N NH1 . ARG H 1 121 ? -8.817  -55.760 39.302  1.00 53.07  ? 121 ARG H NH1 1 
ATOM   23126 N NH2 . ARG H 1 121 ? -8.246  -57.133 37.562  1.00 60.52  ? 121 ARG H NH2 1 
ATOM   23127 N N   . LYS H 1 122 ? -5.838  -50.020 40.056  1.00 36.27  ? 122 LYS H N   1 
ATOM   23128 C CA  . LYS H 1 122 ? -6.343  -49.030 39.108  1.00 40.72  ? 122 LYS H CA  1 
ATOM   23129 C C   . LYS H 1 122 ? -5.244  -48.065 38.679  1.00 41.52  ? 122 LYS H C   1 
ATOM   23130 O O   . LYS H 1 122 ? -5.147  -47.711 37.498  1.00 43.49  ? 122 LYS H O   1 
ATOM   23131 C CB  . LYS H 1 122 ? -7.537  -48.286 39.706  1.00 36.34  ? 122 LYS H CB  1 
ATOM   23132 C CG  . LYS H 1 122 ? -8.872  -48.696 39.061  1.00 40.22  ? 122 LYS H CG  1 
ATOM   23133 C CD  . LYS H 1 122 ? -10.052 -48.375 39.961  1.00 45.65  ? 122 LYS H CD  1 
ATOM   23134 C CE  . LYS H 1 122 ? -9.928  -49.132 41.277  1.00 47.94  ? 122 LYS H CE  1 
ATOM   23135 N NZ  . LYS H 1 122 ? -11.103 -48.996 42.199  1.00 45.18  ? 122 LYS H NZ  1 
ATOM   23136 N N   . LEU H 1 123 ? -4.372  -47.672 39.608  1.00 37.86  ? 123 LEU H N   1 
ATOM   23137 C CA  . LEU H 1 123 ? -3.306  -46.737 39.278  1.00 37.53  ? 123 LEU H CA  1 
ATOM   23138 C C   . LEU H 1 123 ? -2.198  -47.359 38.443  1.00 37.87  ? 123 LEU H C   1 
ATOM   23139 O O   . LEU H 1 123 ? -1.352  -46.622 37.928  1.00 41.62  ? 123 LEU H O   1 
ATOM   23140 C CB  . LEU H 1 123 ? -2.705  -46.164 40.556  1.00 38.42  ? 123 LEU H CB  1 
ATOM   23141 C CG  . LEU H 1 123 ? -3.388  -44.966 41.200  1.00 34.00  ? 123 LEU H CG  1 
ATOM   23142 C CD1 . LEU H 1 123 ? -2.518  -44.487 42.319  1.00 31.36  ? 123 LEU H CD1 1 
ATOM   23143 C CD2 . LEU H 1 123 ? -3.620  -43.853 40.181  1.00 35.47  ? 123 LEU H CD2 1 
ATOM   23144 N N   . ASN H 1 124 ? -2.167  -48.681 38.304  1.00 39.23  ? 124 ASN H N   1 
ATOM   23145 C CA  . ASN H 1 124 ? -1.044  -49.369 37.672  1.00 42.19  ? 124 ASN H CA  1 
ATOM   23146 C C   . ASN H 1 124 ? 0.257   -49.093 38.417  1.00 41.57  ? 124 ASN H C   1 
ATOM   23147 O O   . ASN H 1 124 ? 1.350   -49.112 37.845  1.00 41.26  ? 124 ASN H O   1 
ATOM   23148 C CB  . ASN H 1 124 ? -0.916  -48.998 36.196  1.00 47.89  ? 124 ASN H CB  1 
ATOM   23149 C CG  . ASN H 1 124 ? -0.142  -50.015 35.428  1.00 48.00  ? 124 ASN H CG  1 
ATOM   23150 O OD1 . ASN H 1 124 ? -0.504  -51.190 35.413  1.00 52.84  ? 124 ASN H OD1 1 
ATOM   23151 N ND2 . ASN H 1 124 ? 0.933   -49.583 34.779  1.00 52.38  ? 124 ASN H ND2 1 
ATOM   23152 N N   . VAL H 1 125 ? 0.119   -48.831 39.708  1.00 40.11  ? 125 VAL H N   1 
ATOM   23153 C CA  . VAL H 1 125 ? 1.220   -48.692 40.648  1.00 38.30  ? 125 VAL H CA  1 
ATOM   23154 C C   . VAL H 1 125 ? 1.601   -50.091 41.117  1.00 37.31  ? 125 VAL H C   1 
ATOM   23155 O O   . VAL H 1 125 ? 0.884   -51.053 40.828  1.00 38.52  ? 125 VAL H O   1 
ATOM   23156 C CB  . VAL H 1 125 ? 0.773   -47.738 41.770  1.00 39.84  ? 125 VAL H CB  1 
ATOM   23157 C CG1 . VAL H 1 125 ? 1.455   -47.995 43.059  1.00 37.98  ? 125 VAL H CG1 1 
ATOM   23158 C CG2 . VAL H 1 125 ? 1.005   -46.299 41.320  1.00 38.82  ? 125 VAL H CG2 1 
ATOM   23159 N N   . ALA H 1 126 ? 2.764   -50.239 41.756  1.00 39.86  ? 126 ALA H N   1 
ATOM   23160 C CA  . ALA H 1 126 ? 3.155   -51.524 42.319  1.00 31.78  ? 126 ALA H CA  1 
ATOM   23161 C C   . ALA H 1 126 ? 2.027   -52.108 43.156  1.00 33.41  ? 126 ALA H C   1 
ATOM   23162 O O   . ALA H 1 126 ? 1.422   -51.419 43.984  1.00 29.50  ? 126 ALA H O   1 
ATOM   23163 C CB  . ALA H 1 126 ? 4.412   -51.370 43.175  1.00 35.56  ? 126 ALA H CB  1 
ATOM   23164 N N   . ALA H 1 127 ? 1.733   -53.379 42.917  1.00 30.55  ? 127 ALA H N   1 
ATOM   23165 C CA  . ALA H 1 127 ? 0.675   -54.039 43.652  1.00 30.91  ? 127 ALA H CA  1 
ATOM   23166 C C   . ALA H 1 127 ? 0.936   -53.922 45.148  1.00 29.88  ? 127 ALA H C   1 
ATOM   23167 O O   . ALA H 1 127 ? 2.074   -54.042 45.610  1.00 29.03  ? 127 ALA H O   1 
ATOM   23168 C CB  . ALA H 1 127 ? 0.573   -55.510 43.225  1.00 35.60  ? 127 ALA H CB  1 
ATOM   23169 N N   . LEU H 1 128 ? -0.119  -53.607 45.888  1.00 29.87  ? 128 LEU H N   1 
ATOM   23170 C CA  . LEU H 1 128 ? -0.057  -53.575 47.343  1.00 24.73  ? 128 LEU H CA  1 
ATOM   23171 C C   . LEU H 1 128 ? 0.384   -54.931 47.873  1.00 25.17  ? 128 LEU H C   1 
ATOM   23172 O O   . LEU H 1 128 ? -0.235  -55.951 47.560  1.00 23.62  ? 128 LEU H O   1 
ATOM   23173 C CB  . LEU H 1 128 ? -1.437  -53.216 47.891  1.00 26.90  ? 128 LEU H CB  1 
ATOM   23174 C CG  . LEU H 1 128 ? -1.542  -52.288 49.099  1.00 28.01  ? 128 LEU H CG  1 
ATOM   23175 C CD1 . LEU H 1 128 ? -2.096  -53.036 50.265  1.00 26.64  ? 128 LEU H CD1 1 
ATOM   23176 C CD2 . LEU H 1 128 ? -0.184  -51.683 49.422  1.00 29.05  ? 128 LEU H CD2 1 
ATOM   23177 N N   . ASP H 1 129 ? 1.457   -54.954 48.666  1.00 23.67  ? 129 ASP H N   1 
ATOM   23178 C CA  . ASP H 1 129 ? 1.888   -56.207 49.270  1.00 23.21  ? 129 ASP H CA  1 
ATOM   23179 C C   . ASP H 1 129 ? 0.771   -56.753 50.152  1.00 23.45  ? 129 ASP H C   1 
ATOM   23180 O O   . ASP H 1 129 ? 0.064   -55.996 50.823  1.00 17.40  ? 129 ASP H O   1 
ATOM   23181 C CB  . ASP H 1 129 ? 3.171   -55.992 50.083  1.00 25.38  ? 129 ASP H CB  1 
ATOM   23182 C CG  . ASP H 1 129 ? 3.860   -57.315 50.487  1.00 28.26  ? 129 ASP H CG  1 
ATOM   23183 O OD1 . ASP H 1 129 ? 3.541   -58.378 49.911  1.00 29.56  ? 129 ASP H OD1 1 
ATOM   23184 O OD2 . ASP H 1 129 ? 4.747   -57.283 51.379  1.00 28.33  ? 129 ASP H OD2 1 
ATOM   23185 N N   . GLY H 1 130 ? 0.599   -58.069 50.122  1.00 24.11  ? 130 GLY H N   1 
ATOM   23186 C CA  . GLY H 1 130 ? -0.529  -58.693 50.784  1.00 24.33  ? 130 GLY H CA  1 
ATOM   23187 C C   . GLY H 1 130 ? -1.835  -58.394 50.087  1.00 23.74  ? 130 GLY H C   1 
ATOM   23188 O O   . GLY H 1 130 ? -2.875  -58.274 50.749  1.00 20.08  ? 130 GLY H O   1 
ATOM   23189 N N   . TYR H 1 131 ? -1.801  -58.297 48.756  1.00 26.36  ? 131 TYR H N   1 
ATOM   23190 C CA  . TYR H 1 131 ? -2.924  -57.773 47.985  1.00 29.10  ? 131 TYR H CA  1 
ATOM   23191 C C   . TYR H 1 131 ? -4.195  -58.594 48.213  1.00 27.57  ? 131 TYR H C   1 
ATOM   23192 O O   . TYR H 1 131 ? -5.260  -58.038 48.504  1.00 25.65  ? 131 TYR H O   1 
ATOM   23193 C CB  . TYR H 1 131 ? -2.542  -57.733 46.493  1.00 28.36  ? 131 TYR H CB  1 
ATOM   23194 C CG  . TYR H 1 131 ? -3.689  -57.409 45.566  1.00 26.39  ? 131 TYR H CG  1 
ATOM   23195 C CD1 . TYR H 1 131 ? -4.496  -58.422 45.041  1.00 32.16  ? 131 TYR H CD1 1 
ATOM   23196 C CD2 . TYR H 1 131 ? -3.974  -56.109 45.215  1.00 28.77  ? 131 TYR H CD2 1 
ATOM   23197 C CE1 . TYR H 1 131 ? -5.569  -58.136 44.199  1.00 29.66  ? 131 TYR H CE1 1 
ATOM   23198 C CE2 . TYR H 1 131 ? -5.048  -55.810 44.366  1.00 31.08  ? 131 TYR H CE2 1 
ATOM   23199 C CZ  . TYR H 1 131 ? -5.840  -56.831 43.867  1.00 31.76  ? 131 TYR H CZ  1 
ATOM   23200 O OH  . TYR H 1 131 ? -6.904  -56.547 43.031  1.00 37.93  ? 131 TYR H OH  1 
ATOM   23201 N N   . GLU H 1 132 ? -4.095  -59.924 48.091  1.00 30.03  ? 132 GLU H N   1 
ATOM   23202 C CA  . GLU H 1 132 ? -5.269  -60.784 48.232  1.00 25.10  ? 132 GLU H CA  1 
ATOM   23203 C C   . GLU H 1 132 ? -5.855  -60.719 49.642  1.00 27.28  ? 132 GLU H C   1 
ATOM   23204 O O   . GLU H 1 132 ? -7.086  -60.677 49.805  1.00 21.83  ? 132 GLU H O   1 
ATOM   23205 C CB  . GLU H 1 132 ? -4.904  -62.221 47.850  1.00 25.02  ? 132 GLU H CB  1 
ATOM   23206 C CG  . GLU H 1 132 ? -4.479  -62.401 46.362  1.00 30.15  ? 132 GLU H CG  1 
ATOM   23207 C CD  . GLU H 1 132 ? -5.542  -61.936 45.338  1.00 33.04  ? 132 GLU H CD  1 
ATOM   23208 O OE1 . GLU H 1 132 ? -6.755  -62.129 45.582  1.00 41.88  ? 132 GLU H OE1 1 
ATOM   23209 O OE2 . GLU H 1 132 ? -5.167  -61.375 44.283  1.00 29.40  ? 132 GLU H OE2 1 
ATOM   23210 N N   . PHE H 1 133 ? -4.998  -60.712 50.671  1.00 24.71  ? 133 PHE H N   1 
ATOM   23211 C CA  . PHE H 1 133 ? -5.470  -60.554 52.051  1.00 23.32  ? 133 PHE H CA  1 
ATOM   23212 C C   . PHE H 1 133 ? -6.256  -59.256 52.221  1.00 27.66  ? 133 PHE H C   1 
ATOM   23213 O O   . PHE H 1 133 ? -7.335  -59.239 52.842  1.00 23.07  ? 133 PHE H O   1 
ATOM   23214 C CB  . PHE H 1 133 ? -4.277  -60.594 53.015  1.00 22.69  ? 133 PHE H CB  1 
ATOM   23215 C CG  . PHE H 1 133 ? -4.655  -60.685 54.488  1.00 25.76  ? 133 PHE H CG  1 
ATOM   23216 C CD1 . PHE H 1 133 ? -5.273  -61.819 55.002  1.00 22.72  ? 133 PHE H CD1 1 
ATOM   23217 C CD2 . PHE H 1 133 ? -4.337  -59.650 55.368  1.00 26.29  ? 133 PHE H CD2 1 
ATOM   23218 C CE1 . PHE H 1 133 ? -5.591  -61.915 56.365  1.00 23.66  ? 133 PHE H CE1 1 
ATOM   23219 C CE2 . PHE H 1 133 ? -4.653  -59.737 56.733  1.00 25.52  ? 133 PHE H CE2 1 
ATOM   23220 C CZ  . PHE H 1 133 ? -5.288  -60.869 57.230  1.00 24.83  ? 133 PHE H CZ  1 
ATOM   23221 N N   . ALA H 1 134 ? -5.725  -58.148 51.687  1.00 19.17  ? 134 ALA H N   1 
ATOM   23222 C CA  . ALA H 1 134 ? -6.448  -56.887 51.775  1.00 18.60  ? 134 ALA H CA  1 
ATOM   23223 C C   . ALA H 1 134 ? -7.781  -56.959 51.034  1.00 24.24  ? 134 ALA H C   1 
ATOM   23224 O O   . ALA H 1 134 ? -8.783  -56.403 51.503  1.00 24.22  ? 134 ALA H O   1 
ATOM   23225 C CB  . ALA H 1 134 ? -5.591  -55.744 51.235  1.00 21.36  ? 134 ALA H CB  1 
ATOM   23226 N N   . MET H 1 135 ? -7.827  -57.667 49.895  1.00 21.05  ? 135 MET H N   1 
ATOM   23227 C CA  . MET H 1 135 ? -9.063  -57.692 49.109  1.00 26.26  ? 135 MET H CA  1 
ATOM   23228 C C   . MET H 1 135 ? -10.199 -58.360 49.867  1.00 25.44  ? 135 MET H C   1 
ATOM   23229 O O   . MET H 1 135 ? -11.373 -58.045 49.626  1.00 24.48  ? 135 MET H O   1 
ATOM   23230 C CB  . MET H 1 135 ? -8.860  -58.401 47.766  1.00 22.72  ? 135 MET H CB  1 
ATOM   23231 C CG  . MET H 1 135 ? -8.050  -57.624 46.728  1.00 27.95  ? 135 MET H CG  1 
ATOM   23232 S SD  . MET H 1 135 ? -8.784  -56.041 46.258  1.00 27.00  ? 135 MET H SD  1 
ATOM   23233 C CE  . MET H 1 135 ? -9.605  -56.582 44.740  1.00 22.90  ? 135 MET H CE  1 
ATOM   23234 N N   . GLN H 1 136 ? -9.874  -59.291 50.762  1.00 23.37  ? 136 GLN H N   1 
ATOM   23235 C CA  . GLN H 1 136 ? -10.833 -59.963 51.621  1.00 17.67  ? 136 GLN H CA  1 
ATOM   23236 C C   . GLN H 1 136 ? -11.066 -59.195 52.921  1.00 23.02  ? 136 GLN H C   1 
ATOM   23237 O O   . GLN H 1 136 ? -11.715 -59.712 53.836  1.00 22.60  ? 136 GLN H O   1 
ATOM   23238 C CB  . GLN H 1 136 ? -10.342 -61.392 51.900  1.00 23.86  ? 136 GLN H CB  1 
ATOM   23239 C CG  . GLN H 1 136 ? -10.220 -62.272 50.635  1.00 21.56  ? 136 GLN H CG  1 
ATOM   23240 C CD  . GLN H 1 136 ? -11.474 -62.215 49.755  1.00 27.46  ? 136 GLN H CD  1 
ATOM   23241 O OE1 . GLN H 1 136 ? -12.603 -62.216 50.256  1.00 29.37  ? 136 GLN H OE1 1 
ATOM   23242 N NE2 . GLN H 1 136 ? -11.279 -62.114 48.449  1.00 26.98  ? 136 GLN H NE2 1 
ATOM   23243 N N   . ASN H 1 137 ? -10.563 -57.962 52.997  1.00 26.91  ? 137 ASN H N   1 
ATOM   23244 C CA  . ASN H 1 137 ? -10.579 -57.138 54.203  1.00 22.56  ? 137 ASN H CA  1 
ATOM   23245 C C   . ASN H 1 137 ? -10.018 -57.911 55.393  1.00 22.65  ? 137 ASN H C   1 
ATOM   23246 O O   . ASN H 1 137 ? -10.614 -57.992 56.464  1.00 23.76  ? 137 ASN H O   1 
ATOM   23247 C CB  . ASN H 1 137 ? -11.977 -56.597 54.479  1.00 29.24  ? 137 ASN H CB  1 
ATOM   23248 C CG  . ASN H 1 137 ? -12.268 -55.333 53.674  1.00 33.93  ? 137 ASN H CG  1 
ATOM   23249 O OD1 . ASN H 1 137 ? -11.467 -54.392 53.664  1.00 33.09  ? 137 ASN H OD1 1 
ATOM   23250 N ND2 . ASN H 1 137 ? -13.421 -55.296 53.022  1.00 25.56  ? 137 ASN H ND2 1 
ATOM   23251 N N   . GLY H 1 138 ? -8.838  -58.485 55.187  1.00 23.39  ? 138 GLY H N   1 
ATOM   23252 C CA  . GLY H 1 138 ? -8.189  -59.223 56.252  1.00 20.92  ? 138 GLY H CA  1 
ATOM   23253 C C   . GLY H 1 138 ? -7.900  -58.386 57.483  1.00 24.49  ? 138 GLY H C   1 
ATOM   23254 O O   . GLY H 1 138 ? -8.074  -58.857 58.612  1.00 24.20  ? 138 GLY H O   1 
ATOM   23255 N N   . ILE H 1 139 ? -7.441  -57.139 57.303  1.00 22.80  ? 139 ILE H N   1 
ATOM   23256 C CA  . ILE H 1 139 ? -6.977  -56.449 58.508  1.00 27.24  ? 139 ILE H CA  1 
ATOM   23257 C C   . ILE H 1 139 ? -8.147  -56.083 59.414  1.00 29.67  ? 139 ILE H C   1 
ATOM   23258 O O   . ILE H 1 139 ? -7.972  -55.980 60.636  1.00 26.72  ? 139 ILE H O   1 
ATOM   23259 C CB  . ILE H 1 139 ? -6.108  -55.222 58.187  1.00 27.52  ? 139 ILE H CB  1 
ATOM   23260 C CG1 . ILE H 1 139 ? -6.967  -54.020 57.909  1.00 27.26  ? 139 ILE H CG1 1 
ATOM   23261 C CG2 . ILE H 1 139 ? -5.130  -55.492 57.017  1.00 30.59  ? 139 ILE H CG2 1 
ATOM   23262 C CD1 . ILE H 1 139 ? -6.147  -52.954 57.353  1.00 38.11  ? 139 ILE H CD1 1 
ATOM   23263 N N   . ASP H 1 140 ? -9.356  -55.911 58.857  1.00 28.48  ? 140 ASP H N   1 
ATOM   23264 C CA  . ASP H 1 140 ? -10.523 -55.764 59.718  1.00 28.56  ? 140 ASP H CA  1 
ATOM   23265 C C   . ASP H 1 140 ? -10.613 -56.912 60.711  1.00 32.50  ? 140 ASP H C   1 
ATOM   23266 O O   . ASP H 1 140 ? -10.884 -56.697 61.901  1.00 37.75  ? 140 ASP H O   1 
ATOM   23267 C CB  . ASP H 1 140 ? -11.813 -55.688 58.901  1.00 33.29  ? 140 ASP H CB  1 
ATOM   23268 C CG  . ASP H 1 140 ? -12.087 -54.305 58.367  1.00 38.56  ? 140 ASP H CG  1 
ATOM   23269 O OD1 . ASP H 1 140 ? -11.453 -53.912 57.369  1.00 53.90  ? 140 ASP H OD1 1 
ATOM   23270 O OD2 . ASP H 1 140 ? -12.911 -53.590 58.977  1.00 46.36  ? 140 ASP H OD2 1 
ATOM   23271 N N   . LEU H 1 141 ? -10.377 -58.139 60.243  1.00 28.03  ? 141 LEU H N   1 
ATOM   23272 C CA  . LEU H 1 141 ? -10.348 -59.285 61.143  1.00 26.14  ? 141 LEU H CA  1 
ATOM   23273 C C   . LEU H 1 141 ? -9.229  -59.156 62.174  1.00 29.44  ? 141 LEU H C   1 
ATOM   23274 O O   . LEU H 1 141 ? -9.407  -59.496 63.351  1.00 27.56  ? 141 LEU H O   1 
ATOM   23275 C CB  . LEU H 1 141 ? -10.179 -60.562 60.329  1.00 25.47  ? 141 LEU H CB  1 
ATOM   23276 C CG  . LEU H 1 141 ? -9.669  -61.755 61.117  1.00 23.56  ? 141 LEU H CG  1 
ATOM   23277 C CD1 . LEU H 1 141 ? -10.754 -62.150 62.121  1.00 32.32  ? 141 LEU H CD1 1 
ATOM   23278 C CD2 . LEU H 1 141 ? -9.348  -62.905 60.177  1.00 25.02  ? 141 LEU H CD2 1 
ATOM   23279 N N   . LEU H 1 142 ? -8.071  -58.658 61.754  1.00 25.64  ? 142 LEU H N   1 
ATOM   23280 C CA  . LEU H 1 142 ? -6.936  -58.594 62.659  1.00 26.85  ? 142 LEU H CA  1 
ATOM   23281 C C   . LEU H 1 142 ? -7.106  -57.492 63.684  1.00 27.65  ? 142 LEU H C   1 
ATOM   23282 O O   . LEU H 1 142 ? -6.534  -57.578 64.775  1.00 27.24  ? 142 LEU H O   1 
ATOM   23283 C CB  . LEU H 1 142 ? -5.637  -58.374 61.871  1.00 25.69  ? 142 LEU H CB  1 
ATOM   23284 C CG  . LEU H 1 142 ? -5.009  -59.516 61.052  1.00 20.10  ? 142 LEU H CG  1 
ATOM   23285 C CD1 . LEU H 1 142 ? -3.551  -59.210 60.762  1.00 24.01  ? 142 LEU H CD1 1 
ATOM   23286 C CD2 . LEU H 1 142 ? -5.123  -60.836 61.714  1.00 23.00  ? 142 LEU H CD2 1 
ATOM   23287 N N   . ASN H 1 143 ? -7.877  -56.453 63.348  1.00 28.29  ? 143 ASN H N   1 
ATOM   23288 C CA  . ASN H 1 143 ? -8.024  -55.266 64.173  1.00 28.91  ? 143 ASN H CA  1 
ATOM   23289 C C   . ASN H 1 143 ? -9.204  -55.359 65.144  1.00 33.05  ? 143 ASN H C   1 
ATOM   23290 O O   . ASN H 1 143 ? -9.640  -54.335 65.682  1.00 31.97  ? 143 ASN H O   1 
ATOM   23291 C CB  . ASN H 1 143 ? -8.129  -54.016 63.283  1.00 25.17  ? 143 ASN H CB  1 
ATOM   23292 C CG  . ASN H 1 143 ? -6.731  -53.492 62.837  1.00 30.97  ? 143 ASN H CG  1 
ATOM   23293 O OD1 . ASN H 1 143 ? -5.718  -53.819 63.458  1.00 31.17  ? 143 ASN H OD1 1 
ATOM   23294 N ND2 . ASN H 1 143 ? -6.682  -52.706 61.768  1.00 25.56  ? 143 ASN H ND2 1 
ATOM   23295 N N   . MET H 1 144 ? -9.720  -56.556 65.392  1.00 30.96  ? 144 MET H N   1 
ATOM   23296 C CA  . MET H 1 144 ? -10.729 -56.759 66.421  1.00 30.50  ? 144 MET H CA  1 
ATOM   23297 C C   . MET H 1 144 ? -10.067 -57.271 67.696  1.00 28.03  ? 144 MET H C   1 
ATOM   23298 O O   . MET H 1 144 ? -9.216  -58.165 67.648  1.00 26.50  ? 144 MET H O   1 
ATOM   23299 C CB  . MET H 1 144 ? -11.790 -57.754 65.967  1.00 28.89  ? 144 MET H CB  1 
ATOM   23300 C CG  . MET H 1 144 ? -12.752 -57.278 64.896  1.00 28.70  ? 144 MET H CG  1 
ATOM   23301 S SD  . MET H 1 144 ? -13.441 -58.757 64.107  1.00 35.99  ? 144 MET H SD  1 
ATOM   23302 C CE  . MET H 1 144 ? -13.554 -58.226 62.388  1.00 39.38  ? 144 MET H CE  1 
ATOM   23303 N N   . LYS H 1 145 ? -10.471 -56.717 68.840  1.00 24.02  ? 145 LYS H N   1 
ATOM   23304 C CA  . LYS H 1 145 ? -9.881  -57.163 70.100  1.00 29.61  ? 145 LYS H CA  1 
ATOM   23305 C C   . LYS H 1 145 ? -10.188 -58.627 70.382  1.00 23.28  ? 145 LYS H C   1 
ATOM   23306 O O   . LYS H 1 145 ? -9.336  -59.344 70.913  1.00 19.93  ? 145 LYS H O   1 
ATOM   23307 C CB  . LYS H 1 145 ? -10.353 -56.283 71.251  1.00 29.15  ? 145 LYS H CB  1 
ATOM   23308 C CG  . LYS H 1 145 ? -9.593  -54.950 71.277  1.00 36.17  ? 145 LYS H CG  1 
ATOM   23309 C CD  . LYS H 1 145 ? -10.424 -53.823 71.854  1.00 36.14  ? 145 LYS H CD  1 
ATOM   23310 C CE  . LYS H 1 145 ? -9.656  -52.524 71.788  1.00 36.78  ? 145 LYS H CE  1 
ATOM   23311 N NZ  . LYS H 1 145 ? -10.155 -51.699 70.651  1.00 43.57  ? 145 LYS H NZ  1 
ATOM   23312 N N   . SER H 1 146 ? -11.362 -59.103 69.977  1.00 24.51  ? 146 SER H N   1 
ATOM   23313 C CA  . SER H 1 146 ? -11.669 -60.527 70.122  1.00 29.57  ? 146 SER H CA  1 
ATOM   23314 C C   . SER H 1 146 ? -10.652 -61.411 69.397  1.00 24.85  ? 146 SER H C   1 
ATOM   23315 O O   . SER H 1 146 ? -10.275 -62.473 69.909  1.00 25.70  ? 146 SER H O   1 
ATOM   23316 C CB  . SER H 1 146 ? -13.080 -60.824 69.616  1.00 24.69  ? 146 SER H CB  1 
ATOM   23317 O OG  . SER H 1 146 ? -13.275 -60.315 68.316  1.00 27.94  ? 146 SER H OG  1 
ATOM   23318 N N   . THR H 1 147 ? -10.195 -60.997 68.208  1.00 23.64  ? 147 THR H N   1 
ATOM   23319 C CA  . THR H 1 147 ? -9.246  -61.827 67.463  1.00 18.77  ? 147 THR H CA  1 
ATOM   23320 C C   . THR H 1 147 ? -7.914  -61.921 68.188  1.00 21.71  ? 147 THR H C   1 
ATOM   23321 O O   . THR H 1 147 ? -7.318  -63.004 68.276  1.00 24.24  ? 147 THR H O   1 
ATOM   23322 C CB  . THR H 1 147 ? -9.018  -61.263 66.064  1.00 25.73  ? 147 THR H CB  1 
ATOM   23323 O OG1 . THR H 1 147 ? -10.262 -61.203 65.354  1.00 23.30  ? 147 THR H OG1 1 
ATOM   23324 C CG2 . THR H 1 147 ? -8.030  -62.147 65.287  1.00 18.64  ? 147 THR H CG2 1 
ATOM   23325 N N   . PHE H 1 148 ? -7.405  -60.790 68.679  1.00 20.15  ? 148 PHE H N   1 
ATOM   23326 C CA  . PHE H 1 148 ? -6.162  -60.835 69.431  1.00 20.86  ? 148 PHE H CA  1 
ATOM   23327 C C   . PHE H 1 148 ? -6.281  -61.804 70.587  1.00 22.62  ? 148 PHE H C   1 
ATOM   23328 O O   . PHE H 1 148 ? -5.387  -62.616 70.846  1.00 22.61  ? 148 PHE H O   1 
ATOM   23329 C CB  . PHE H 1 148 ? -5.795  -59.452 69.977  1.00 20.47  ? 148 PHE H CB  1 
ATOM   23330 C CG  . PHE H 1 148 ? -4.630  -59.506 70.890  1.00 23.99  ? 148 PHE H CG  1 
ATOM   23331 C CD1 . PHE H 1 148 ? -3.349  -59.541 70.374  1.00 21.19  ? 148 PHE H CD1 1 
ATOM   23332 C CD2 . PHE H 1 148 ? -4.807  -59.644 72.250  1.00 19.68  ? 148 PHE H CD2 1 
ATOM   23333 C CE1 . PHE H 1 148 ? -2.276  -59.652 71.199  1.00 24.20  ? 148 PHE H CE1 1 
ATOM   23334 C CE2 . PHE H 1 148 ? -3.736  -59.752 73.076  1.00 23.78  ? 148 PHE H CE2 1 
ATOM   23335 C CZ  . PHE H 1 148 ? -2.461  -59.753 72.554  1.00 25.47  ? 148 PHE H CZ  1 
ATOM   23336 N N   . ARG H 1 149 ? -7.375  -61.686 71.327  1.00 21.13  ? 149 ARG H N   1 
ATOM   23337 C CA  . ARG H 1 149 ? -7.571  -62.508 72.501  1.00 24.66  ? 149 ARG H CA  1 
ATOM   23338 C C   . ARG H 1 149 ? -7.590  -63.989 72.128  1.00 26.63  ? 149 ARG H C   1 
ATOM   23339 O O   . ARG H 1 149 ? -7.026  -64.831 72.839  1.00 24.02  ? 149 ARG H O   1 
ATOM   23340 C CB  . ARG H 1 149 ? -8.864  -62.046 73.165  1.00 26.97  ? 149 ARG H CB  1 
ATOM   23341 C CG  . ARG H 1 149 ? -9.193  -62.748 74.373  1.00 30.99  ? 149 ARG H CG  1 
ATOM   23342 C CD  . ARG H 1 149 ? -9.585  -61.820 75.518  1.00 31.72  ? 149 ARG H CD  1 
ATOM   23343 N NE  . ARG H 1 149 ? -9.372  -62.619 76.716  1.00 25.98  ? 149 ARG H NE  1 
ATOM   23344 C CZ  . ARG H 1 149 ? -8.368  -62.430 77.552  1.00 27.82  ? 149 ARG H CZ  1 
ATOM   23345 N NH1 . ARG H 1 149 ? -7.644  -61.318 77.523  1.00 28.72  ? 149 ARG H NH1 1 
ATOM   23346 N NH2 . ARG H 1 149 ? -8.085  -63.371 78.441  1.00 29.35  ? 149 ARG H NH2 1 
ATOM   23347 N N   . ARG H 1 150 ? -8.185  -64.312 70.976  1.00 25.72  ? 150 ARG H N   1 
ATOM   23348 C CA  . ARG H 1 150 ? -8.276  -65.695 70.522  1.00 23.24  ? 150 ARG H CA  1 
ATOM   23349 C C   . ARG H 1 150 ? -6.943  -66.185 69.999  1.00 23.04  ? 150 ARG H C   1 
ATOM   23350 O O   . ARG H 1 150 ? -6.453  -67.240 70.427  1.00 23.37  ? 150 ARG H O   1 
ATOM   23351 C CB  . ARG H 1 150 ? -9.333  -65.823 69.435  1.00 21.18  ? 150 ARG H CB  1 
ATOM   23352 C CG  . ARG H 1 150 ? -10.727 -65.798 69.977  1.00 27.92  ? 150 ARG H CG  1 
ATOM   23353 C CD  . ARG H 1 150 ? -11.725 -65.278 68.962  1.00 27.50  ? 150 ARG H CD  1 
ATOM   23354 N NE  . ARG H 1 150 ? -13.075 -65.434 69.483  1.00 26.99  ? 150 ARG H NE  1 
ATOM   23355 C CZ  . ARG H 1 150 ? -14.182 -65.167 68.805  1.00 26.48  ? 150 ARG H CZ  1 
ATOM   23356 N NH1 . ARG H 1 150 ? -14.138 -64.632 67.605  1.00 19.92  ? 150 ARG H NH1 1 
ATOM   23357 N NH2 . ARG H 1 150 ? -15.365 -65.465 69.347  1.00 27.37  ? 150 ARG H NH2 1 
ATOM   23358 N N   . LEU H 1 151 ? -6.347  -65.439 69.063  1.00 22.50  ? 151 LEU H N   1 
ATOM   23359 C CA  . LEU H 1 151 ? -5.029  -65.816 68.579  1.00 23.18  ? 151 LEU H CA  1 
ATOM   23360 C C   . LEU H 1 151 ? -4.049  -65.920 69.735  1.00 23.45  ? 151 LEU H C   1 
ATOM   23361 O O   . LEU H 1 151 ? -3.247  -66.856 69.790  1.00 28.24  ? 151 LEU H O   1 
ATOM   23362 C CB  . LEU H 1 151 ? -4.514  -64.819 67.528  1.00 21.98  ? 151 LEU H CB  1 
ATOM   23363 C CG  . LEU H 1 151 ? -5.264  -64.689 66.184  1.00 27.72  ? 151 LEU H CG  1 
ATOM   23364 C CD1 . LEU H 1 151 ? -4.615  -63.674 65.259  1.00 28.82  ? 151 LEU H CD1 1 
ATOM   23365 C CD2 . LEU H 1 151 ? -5.372  -66.003 65.456  1.00 26.67  ? 151 LEU H CD2 1 
ATOM   23366 N N   . ALA H 1 152 ? -4.106  -64.980 70.681  1.00 22.69  ? 152 ALA H N   1 
ATOM   23367 C CA  . ALA H 1 152 ? -3.122  -64.996 71.758  1.00 22.30  ? 152 ALA H CA  1 
ATOM   23368 C C   . ALA H 1 152 ? -3.270  -66.242 72.622  1.00 27.16  ? 152 ALA H C   1 
ATOM   23369 O O   . ALA H 1 152 ? -2.269  -66.894 72.965  1.00 26.24  ? 152 ALA H O   1 
ATOM   23370 C CB  . ALA H 1 152 ? -3.250  -63.741 72.610  1.00 24.67  ? 152 ALA H CB  1 
ATOM   23371 N N   . ALA H 1 153 ? -4.514  -66.600 72.966  1.00 22.90  ? 153 ALA H N   1 
ATOM   23372 C CA  . ALA H 1 153 ? -4.750  -67.760 73.825  1.00 22.67  ? 153 ALA H CA  1 
ATOM   23373 C C   . ALA H 1 153 ? -4.384  -69.059 73.123  1.00 22.90  ? 153 ALA H C   1 
ATOM   23374 O O   . ALA H 1 153 ? -3.884  -69.994 73.754  1.00 24.47  ? 153 ALA H O   1 
ATOM   23375 C CB  . ALA H 1 153 ? -6.212  -67.788 74.265  1.00 22.85  ? 153 ALA H CB  1 
ATOM   23376 N N   . GLY H 1 154 ? -4.640  -69.147 71.821  1.00 20.24  ? 154 GLY H N   1 
ATOM   23377 C CA  . GLY H 1 154 ? -4.285  -70.353 71.097  1.00 24.99  ? 154 GLY H CA  1 
ATOM   23378 C C   . GLY H 1 154 ? -2.789  -70.512 70.928  1.00 27.06  ? 154 GLY H C   1 
ATOM   23379 O O   . GLY H 1 154 ? -2.274  -71.631 70.948  1.00 26.09  ? 154 GLY H O   1 
ATOM   23380 N N   . LEU H 1 155 ? -2.072  -69.400 70.777  1.00 29.25  ? 155 LEU H N   1 
ATOM   23381 C CA  . LEU H 1 155 ? -0.629  -69.455 70.569  1.00 31.69  ? 155 LEU H CA  1 
ATOM   23382 C C   . LEU H 1 155 ? 0.131   -69.668 71.866  1.00 28.37  ? 155 LEU H C   1 
ATOM   23383 O O   . LEU H 1 155 ? 1.251   -70.183 71.838  1.00 29.62  ? 155 LEU H O   1 
ATOM   23384 C CB  . LEU H 1 155 ? -0.142  -68.163 69.901  1.00 31.38  ? 155 LEU H CB  1 
ATOM   23385 C CG  . LEU H 1 155 ? 0.543   -68.238 68.539  1.00 32.06  ? 155 LEU H CG  1 
ATOM   23386 C CD1 . LEU H 1 155 ? 1.146   -66.870 68.223  1.00 34.18  ? 155 LEU H CD1 1 
ATOM   23387 C CD2 . LEU H 1 155 ? 1.615   -69.292 68.542  1.00 31.59  ? 155 LEU H CD2 1 
ATOM   23388 N N   . GLY H 1 156 ? -0.445  -69.281 72.999  1.00 27.06  ? 156 GLY H N   1 
ATOM   23389 C CA  . GLY H 1 156 ? 0.291   -69.227 74.249  1.00 25.40  ? 156 GLY H CA  1 
ATOM   23390 C C   . GLY H 1 156 ? 0.822   -67.856 74.621  1.00 28.48  ? 156 GLY H C   1 
ATOM   23391 O O   . GLY H 1 156 ? 1.560   -67.743 75.605  1.00 25.45  ? 156 GLY H O   1 
ATOM   23392 N N   . THR H 1 157 ? 0.465   -66.815 73.875  1.00 24.38  ? 157 THR H N   1 
ATOM   23393 C CA  . THR H 1 157 ? 0.946   -65.480 74.184  1.00 28.06  ? 157 THR H CA  1 
ATOM   23394 C C   . THR H 1 157 ? 0.392   -65.011 75.531  1.00 23.94  ? 157 THR H C   1 
ATOM   23395 O O   . THR H 1 157 ? -0.783  -65.230 75.827  1.00 25.67  ? 157 THR H O   1 
ATOM   23396 C CB  . THR H 1 157 ? 0.542   -64.519 73.066  1.00 24.68  ? 157 THR H CB  1 
ATOM   23397 O OG1 . THR H 1 157 ? 1.045   -65.012 71.818  1.00 26.86  ? 157 THR H OG1 1 
ATOM   23398 C CG2 . THR H 1 157 ? 1.094   -63.117 73.322  1.00 29.25  ? 157 THR H CG2 1 
ATOM   23399 N N   . PRO H 1 158 ? 1.204   -64.374 76.369  1.00 25.47  ? 158 PRO H N   1 
ATOM   23400 C CA  . PRO H 1 158 ? 0.714   -63.973 77.693  1.00 30.64  ? 158 PRO H CA  1 
ATOM   23401 C C   . PRO H 1 158 ? -0.403  -62.956 77.588  1.00 26.59  ? 158 PRO H C   1 
ATOM   23402 O O   . PRO H 1 158 ? -0.337  -62.000 76.810  1.00 24.57  ? 158 PRO H O   1 
ATOM   23403 C CB  . PRO H 1 158 ? 1.951   -63.383 78.380  1.00 30.49  ? 158 PRO H CB  1 
ATOM   23404 C CG  . PRO H 1 158 ? 3.102   -63.862 77.599  1.00 26.92  ? 158 PRO H CG  1 
ATOM   23405 C CD  . PRO H 1 158 ? 2.632   -64.070 76.196  1.00 29.20  ? 158 PRO H CD  1 
ATOM   23406 N N   . LEU H 1 159 ? -1.416  -63.156 78.424  1.00 27.99  ? 159 LEU H N   1 
ATOM   23407 C CA  . LEU H 1 159 ? -2.739  -62.596 78.203  1.00 31.93  ? 159 LEU H CA  1 
ATOM   23408 C C   . LEU H 1 159 ? -3.449  -62.517 79.542  1.00 31.03  ? 159 LEU H C   1 
ATOM   23409 O O   . LEU H 1 159 ? -3.486  -63.509 80.274  1.00 29.92  ? 159 LEU H O   1 
ATOM   23410 C CB  . LEU H 1 159 ? -3.518  -63.498 77.252  1.00 28.34  ? 159 LEU H CB  1 
ATOM   23411 C CG  . LEU H 1 159 ? -4.794  -63.026 76.597  1.00 29.61  ? 159 LEU H CG  1 
ATOM   23412 C CD1 . LEU H 1 159 ? -4.515  -61.792 75.811  1.00 33.23  ? 159 LEU H CD1 1 
ATOM   23413 C CD2 . LEU H 1 159 ? -5.286  -64.122 75.679  1.00 32.65  ? 159 LEU H CD2 1 
ATOM   23414 N N   . THR H 1 160 ? -4.007  -61.354 79.863  1.00 30.42  ? 160 THR H N   1 
ATOM   23415 C CA  . THR H 1 160 ? -4.727  -61.231 81.119  1.00 31.09  ? 160 THR H CA  1 
ATOM   23416 C C   . THR H 1 160 ? -6.024  -62.019 81.025  1.00 30.62  ? 160 THR H C   1 
ATOM   23417 O O   . THR H 1 160 ? -6.548  -62.263 79.934  1.00 26.13  ? 160 THR H O   1 
ATOM   23418 C CB  . THR H 1 160 ? -5.020  -59.761 81.449  1.00 31.33  ? 160 THR H CB  1 
ATOM   23419 O OG1 . THR H 1 160 ? -6.139  -59.317 80.679  1.00 34.25  ? 160 THR H OG1 1 
ATOM   23420 C CG2 . THR H 1 160 ? -3.832  -58.882 81.113  1.00 31.96  ? 160 THR H CG2 1 
ATOM   23421 N N   . ASP H 1 161 ? -6.537  -62.442 82.177  1.00 28.57  ? 161 ASP H N   1 
ATOM   23422 C CA  . ASP H 1 161 ? -7.801  -63.160 82.159  1.00 27.47  ? 161 ASP H CA  1 
ATOM   23423 C C   . ASP H 1 161 ? -8.884  -62.261 81.583  1.00 25.69  ? 161 ASP H C   1 
ATOM   23424 O O   . ASP H 1 161 ? -8.981  -61.084 81.938  1.00 27.28  ? 161 ASP H O   1 
ATOM   23425 C CB  . ASP H 1 161 ? -8.160  -63.627 83.564  1.00 29.43  ? 161 ASP H CB  1 
ATOM   23426 C CG  . ASP H 1 161 ? -7.132  -64.576 84.123  1.00 38.32  ? 161 ASP H CG  1 
ATOM   23427 O OD1 . ASP H 1 161 ? -6.494  -65.312 83.329  1.00 34.24  ? 161 ASP H OD1 1 
ATOM   23428 O OD2 . ASP H 1 161 ? -6.925  -64.553 85.353  1.00 51.41  ? 161 ASP H OD2 1 
ATOM   23429 N N   . GLY H 1 162 ? -9.680  -62.810 80.675  1.00 24.19  ? 162 GLY H N   1 
ATOM   23430 C CA  . GLY H 1 162 ? -10.728 -62.021 80.061  1.00 23.43  ? 162 GLY H CA  1 
ATOM   23431 C C   . GLY H 1 162 ? -11.699 -62.892 79.301  1.00 22.21  ? 162 GLY H C   1 
ATOM   23432 O O   . GLY H 1 162 ? -11.461 -64.078 79.066  1.00 25.85  ? 162 GLY H O   1 
ATOM   23433 N N   . VAL H 1 163 ? -12.785 -62.264 78.892  1.00 25.58  ? 163 VAL H N   1 
ATOM   23434 C CA  . VAL H 1 163 ? -13.895 -62.917 78.225  1.00 23.25  ? 163 VAL H CA  1 
ATOM   23435 C C   . VAL H 1 163 ? -14.219 -62.141 76.951  1.00 29.22  ? 163 VAL H C   1 
ATOM   23436 O O   . VAL H 1 163 ? -14.220 -60.905 76.955  1.00 31.09  ? 163 VAL H O   1 
ATOM   23437 C CB  . VAL H 1 163 ? -15.121 -62.980 79.164  1.00 23.91  ? 163 VAL H CB  1 
ATOM   23438 C CG1 . VAL H 1 163 ? -16.384 -63.333 78.399  1.00 29.70  ? 163 VAL H CG1 1 
ATOM   23439 C CG2 . VAL H 1 163 ? -14.883 -63.977 80.288  1.00 26.73  ? 163 VAL H CG2 1 
ATOM   23440 N N   . VAL H 1 164 ? -14.467 -62.862 75.855  1.00 30.02  ? 164 VAL H N   1 
ATOM   23441 C CA  . VAL H 1 164 ? -15.125 -62.298 74.676  1.00 29.02  ? 164 VAL H CA  1 
ATOM   23442 C C   . VAL H 1 164 ? -16.626 -62.447 74.921  1.00 33.54  ? 164 VAL H C   1 
ATOM   23443 O O   . VAL H 1 164 ? -17.197 -63.521 74.715  1.00 27.34  ? 164 VAL H O   1 
ATOM   23444 C CB  . VAL H 1 164 ? -14.702 -62.995 73.383  1.00 24.90  ? 164 VAL H CB  1 
ATOM   23445 C CG1 . VAL H 1 164 ? -15.443 -62.391 72.217  1.00 26.74  ? 164 VAL H CG1 1 
ATOM   23446 C CG2 . VAL H 1 164 ? -13.176 -62.915 73.156  1.00 22.96  ? 164 VAL H CG2 1 
ATOM   23447 N N   . ALA H 1 165 ? -17.264 -61.369 75.377  1.00 31.75  ? 165 ALA H N   1 
ATOM   23448 C CA  . ALA H 1 165 ? -18.634 -61.419 75.881  1.00 31.21  ? 165 ALA H CA  1 
ATOM   23449 C C   . ALA H 1 165 ? -19.633 -61.219 74.754  1.00 31.37  ? 165 ALA H C   1 
ATOM   23450 O O   . ALA H 1 165 ? -19.451 -60.358 73.888  1.00 32.79  ? 165 ALA H O   1 
ATOM   23451 C CB  . ALA H 1 165 ? -18.860 -60.351 76.955  1.00 28.62  ? 165 ALA H CB  1 
ATOM   23452 N N   . ARG H 1 166 ? -20.713 -61.992 74.799  1.00 28.73  ? 166 ARG H N   1 
ATOM   23453 C CA  . ARG H 1 166 ? -21.656 -62.068 73.695  1.00 30.90  ? 166 ARG H CA  1 
ATOM   23454 C C   . ARG H 1 166 ? -22.989 -61.403 73.987  1.00 32.01  ? 166 ARG H C   1 
ATOM   23455 O O   . ARG H 1 166 ? -23.792 -61.235 73.058  1.00 34.80  ? 166 ARG H O   1 
ATOM   23456 C CB  . ARG H 1 166 ? -21.882 -63.536 73.306  1.00 28.48  ? 166 ARG H CB  1 
ATOM   23457 C CG  . ARG H 1 166 ? -20.702 -64.099 72.473  1.00 32.67  ? 166 ARG H CG  1 
ATOM   23458 C CD  . ARG H 1 166 ? -20.622 -65.611 72.534  1.00 31.57  ? 166 ARG H CD  1 
ATOM   23459 N NE  . ARG H 1 166 ? -20.341 -66.067 73.893  1.00 32.62  ? 166 ARG H NE  1 
ATOM   23460 C CZ  . ARG H 1 166 ? -20.365 -67.334 74.283  1.00 32.85  ? 166 ARG H CZ  1 
ATOM   23461 N NH1 . ARG H 1 166 ? -20.637 -68.313 73.435  1.00 27.40  ? 166 ARG H NH1 1 
ATOM   23462 N NH2 . ARG H 1 166 ? -20.094 -67.628 75.552  1.00 30.03  ? 166 ARG H NH2 1 
ATOM   23463 N N   . GLY H 1 167 ? -23.242 -61.008 75.232  1.00 30.57  ? 167 GLY H N   1 
ATOM   23464 C CA  . GLY H 1 167 ? -24.403 -60.217 75.568  1.00 30.97  ? 167 GLY H CA  1 
ATOM   23465 C C   . GLY H 1 167 ? -24.320 -59.638 76.965  1.00 30.57  ? 167 GLY H C   1 
ATOM   23466 O O   . GLY H 1 167 ? -23.329 -59.817 77.673  1.00 34.97  ? 167 GLY H O   1 
ATOM   23467 N N   . PRO H 1 168 ? -25.371 -58.925 77.385  1.00 34.34  ? 168 PRO H N   1 
ATOM   23468 C CA  . PRO H 1 168 ? -25.407 -58.385 78.758  1.00 30.96  ? 168 PRO H CA  1 
ATOM   23469 C C   . PRO H 1 168 ? -25.069 -59.385 79.854  1.00 30.99  ? 168 PRO H C   1 
ATOM   23470 O O   . PRO H 1 168 ? -24.313 -59.037 80.774  1.00 33.30  ? 168 PRO H O   1 
ATOM   23471 C CB  . PRO H 1 168 ? -26.858 -57.897 78.896  1.00 33.70  ? 168 PRO H CB  1 
ATOM   23472 C CG  . PRO H 1 168 ? -27.311 -57.608 77.511  1.00 27.95  ? 168 PRO H CG  1 
ATOM   23473 C CD  . PRO H 1 168 ? -26.530 -58.497 76.576  1.00 29.26  ? 168 PRO H CD  1 
ATOM   23474 N N   . ALA H 1 169 ? -25.619 -60.606 79.802  1.00 29.02  ? 169 ALA H N   1 
ATOM   23475 C CA  . ALA H 1 169 ? -25.413 -61.548 80.906  1.00 31.64  ? 169 ALA H CA  1 
ATOM   23476 C C   . ALA H 1 169 ? -23.994 -62.088 80.947  1.00 34.57  ? 169 ALA H C   1 
ATOM   23477 O O   . ALA H 1 169 ? -23.510 -62.476 82.022  1.00 34.97  ? 169 ALA H O   1 
ATOM   23478 C CB  . ALA H 1 169 ? -26.390 -62.723 80.832  1.00 22.97  ? 169 ALA H CB  1 
ATOM   23479 N N   . GLU H 1 170 ? -23.319 -62.167 79.798  1.00 36.90  ? 170 GLU H N   1 
ATOM   23480 C CA  . GLU H 1 170 ? -21.919 -62.557 79.861  1.00 32.47  ? 170 GLU H CA  1 
ATOM   23481 C C   . GLU H 1 170 ? -21.065 -61.421 80.397  1.00 32.61  ? 170 GLU H C   1 
ATOM   23482 O O   . GLU H 1 170 ? -20.073 -61.664 81.099  1.00 29.00  ? 170 GLU H O   1 
ATOM   23483 C CB  . GLU H 1 170 ? -21.418 -62.990 78.495  1.00 34.25  ? 170 GLU H CB  1 
ATOM   23484 C CG  . GLU H 1 170 ? -20.134 -63.792 78.557  1.00 31.86  ? 170 GLU H CG  1 
ATOM   23485 C CD  . GLU H 1 170 ? -20.112 -64.877 77.511  1.00 34.71  ? 170 GLU H CD  1 
ATOM   23486 O OE1 . GLU H 1 170 ? -20.693 -64.642 76.417  1.00 35.52  ? 170 GLU H OE1 1 
ATOM   23487 O OE2 . GLU H 1 170 ? -19.509 -65.942 77.771  1.00 31.57  ? 170 GLU H OE2 1 
ATOM   23488 N N   . VAL H 1 171 ? -21.430 -60.175 80.087  1.00 28.78  ? 171 VAL H N   1 
ATOM   23489 C CA  . VAL H 1 171 ? -20.708 -59.056 80.679  1.00 28.09  ? 171 VAL H CA  1 
ATOM   23490 C C   . VAL H 1 171 ? -20.859 -59.089 82.196  1.00 26.34  ? 171 VAL H C   1 
ATOM   23491 O O   . VAL H 1 171 ? -19.881 -58.944 82.934  1.00 28.55  ? 171 VAL H O   1 
ATOM   23492 C CB  . VAL H 1 171 ? -21.179 -57.718 80.076  1.00 27.77  ? 171 VAL H CB  1 
ATOM   23493 C CG1 . VAL H 1 171 ? -20.581 -56.576 80.850  1.00 28.41  ? 171 VAL H CG1 1 
ATOM   23494 C CG2 . VAL H 1 171 ? -20.755 -57.600 78.598  1.00 25.30  ? 171 VAL H CG2 1 
ATOM   23495 N N   . ARG H 1 172 ? -22.076 -59.335 82.679  1.00 29.14  ? 172 ARG H N   1 
ATOM   23496 C CA  . ARG H 1 172 ? -22.325 -59.406 84.115  1.00 31.35  ? 172 ARG H CA  1 
ATOM   23497 C C   . ARG H 1 172 ? -21.465 -60.480 84.783  1.00 31.22  ? 172 ARG H C   1 
ATOM   23498 O O   . ARG H 1 172 ? -20.676 -60.182 85.689  1.00 28.17  ? 172 ARG H O   1 
ATOM   23499 C CB  . ARG H 1 172 ? -23.815 -59.656 84.370  1.00 36.55  ? 172 ARG H CB  1 
ATOM   23500 C CG  . ARG H 1 172 ? -24.242 -59.382 85.796  1.00 36.58  ? 172 ARG H CG  1 
ATOM   23501 C CD  . ARG H 1 172 ? -25.603 -59.977 86.098  1.00 36.43  ? 172 ARG H CD  1 
ATOM   23502 N NE  . ARG H 1 172 ? -26.110 -59.472 87.368  1.00 39.70  ? 172 ARG H NE  1 
ATOM   23503 C CZ  . ARG H 1 172 ? -25.835 -59.988 88.561  1.00 39.52  ? 172 ARG H CZ  1 
ATOM   23504 N NH1 . ARG H 1 172 ? -25.096 -61.080 88.695  1.00 33.68  ? 172 ARG H NH1 1 
ATOM   23505 N NH2 . ARG H 1 172 ? -26.311 -59.389 89.649  1.00 38.78  ? 172 ARG H NH2 1 
ATOM   23506 N N   . SER H 1 173 ? -21.587 -61.739 84.336  1.00 29.34  ? 173 SER H N   1 
ATOM   23507 C CA  . SER H 1 173 ? -20.802 -62.807 84.956  1.00 29.96  ? 173 SER H CA  1 
ATOM   23508 C C   . SER H 1 173 ? -19.305 -62.599 84.773  1.00 33.14  ? 173 SER H C   1 
ATOM   23509 O O   . SER H 1 173 ? -18.509 -63.024 85.623  1.00 37.53  ? 173 SER H O   1 
ATOM   23510 C CB  . SER H 1 173 ? -21.198 -64.169 84.397  1.00 28.26  ? 173 SER H CB  1 
ATOM   23511 O OG  . SER H 1 173 ? -21.549 -64.062 83.035  1.00 42.07  ? 173 SER H OG  1 
ATOM   23512 N N   . ALA H 1 174 ? -18.893 -61.972 83.673  1.00 30.27  ? 174 ALA H N   1 
ATOM   23513 C CA  . ALA H 1 174 ? -17.465 -61.745 83.489  1.00 31.07  ? 174 ALA H CA  1 
ATOM   23514 C C   . ALA H 1 174 ? -16.960 -60.667 84.439  1.00 31.66  ? 174 ALA H C   1 
ATOM   23515 O O   . ALA H 1 174 ? -15.889 -60.817 85.032  1.00 29.12  ? 174 ALA H O   1 
ATOM   23516 C CB  . ALA H 1 174 ? -17.153 -61.373 82.039  1.00 26.37  ? 174 ALA H CB  1 
ATOM   23517 N N   . ILE H 1 175 ? -17.716 -59.573 84.598  1.00 28.89  ? 175 ILE H N   1 
ATOM   23518 C CA  . ILE H 1 175 ? -17.313 -58.546 85.552  1.00 30.56  ? 175 ILE H CA  1 
ATOM   23519 C C   . ILE H 1 175 ? -17.184 -59.152 86.935  1.00 32.57  ? 175 ILE H C   1 
ATOM   23520 O O   . ILE H 1 175 ? -16.208 -58.899 87.652  1.00 34.64  ? 175 ILE H O   1 
ATOM   23521 C CB  . ILE H 1 175 ? -18.303 -57.367 85.557  1.00 29.48  ? 175 ILE H CB  1 
ATOM   23522 C CG1 . ILE H 1 175 ? -18.270 -56.627 84.232  1.00 32.07  ? 175 ILE H CG1 1 
ATOM   23523 C CG2 . ILE H 1 175 ? -17.934 -56.370 86.646  1.00 29.00  ? 175 ILE H CG2 1 
ATOM   23524 C CD1 . ILE H 1 175 ? -19.410 -55.692 84.065  1.00 29.49  ? 175 ILE H CD1 1 
ATOM   23525 N N   . GLN H 1 176 ? -18.155 -59.983 87.321  1.00 34.05  ? 176 GLN H N   1 
ATOM   23526 C CA  . GLN H 1 176 ? -18.138 -60.565 88.655  1.00 37.51  ? 176 GLN H CA  1 
ATOM   23527 C C   . GLN H 1 176 ? -16.874 -61.388 88.868  1.00 37.45  ? 176 GLN H C   1 
ATOM   23528 O O   . GLN H 1 176 ? -16.126 -61.161 89.826  1.00 38.07  ? 176 GLN H O   1 
ATOM   23529 C CB  . GLN H 1 176 ? -19.392 -61.415 88.880  1.00 40.43  ? 176 GLN H CB  1 
ATOM   23530 C CG  . GLN H 1 176 ? -19.353 -62.186 90.197  1.00 39.93  ? 176 GLN H CG  1 
ATOM   23531 C CD  . GLN H 1 176 ? -20.661 -62.132 90.945  1.00 43.47  ? 176 GLN H CD  1 
ATOM   23532 O OE1 . GLN H 1 176 ? -21.721 -62.397 90.381  1.00 45.70  ? 176 GLN H OE1 1 
ATOM   23533 N NE2 . GLN H 1 176 ? -20.598 -61.780 92.226  1.00 47.81  ? 176 GLN H NE2 1 
ATOM   23534 N N   . GLU H 1 177 ? -16.598 -62.329 87.965  1.00 37.46  ? 177 GLU H N   1 
ATOM   23535 C CA  . GLU H 1 177 ? -15.434 -63.193 88.140  1.00 39.75  ? 177 GLU H CA  1 
ATOM   23536 C C   . GLU H 1 177 ? -14.107 -62.470 87.911  1.00 39.43  ? 177 GLU H C   1 
ATOM   23537 O O   . GLU H 1 177 ? -13.082 -62.904 88.448  1.00 42.20  ? 177 GLU H O   1 
ATOM   23538 C CB  . GLU H 1 177 ? -15.529 -64.392 87.202  1.00 43.33  ? 177 GLU H CB  1 
ATOM   23539 C CG  . GLU H 1 177 ? -15.234 -65.731 87.874  1.00 55.34  ? 177 GLU H CG  1 
ATOM   23540 C CD  . GLU H 1 177 ? -15.168 -66.872 86.877  1.00 59.47  ? 177 GLU H CD  1 
ATOM   23541 O OE1 . GLU H 1 177 ? -15.797 -67.925 87.135  1.00 60.24  ? 177 GLU H OE1 1 
ATOM   23542 O OE2 . GLU H 1 177 ? -14.484 -66.714 85.838  1.00 61.19  ? 177 GLU H OE2 1 
ATOM   23543 N N   . LEU H 1 178 ? -14.085 -61.390 87.131  1.00 33.71  ? 178 LEU H N   1 
ATOM   23544 C CA  . LEU H 1 178 ? -12.808 -60.759 86.806  1.00 33.65  ? 178 LEU H CA  1 
ATOM   23545 C C   . LEU H 1 178 ? -12.400 -59.672 87.788  1.00 34.38  ? 178 LEU H C   1 
ATOM   23546 O O   . LEU H 1 178 ? -11.213 -59.315 87.833  1.00 34.62  ? 178 LEU H O   1 
ATOM   23547 C CB  . LEU H 1 178 ? -12.852 -60.164 85.398  1.00 28.83  ? 178 LEU H CB  1 
ATOM   23548 C CG  . LEU H 1 178 ? -12.952 -61.244 84.332  1.00 30.85  ? 178 LEU H CG  1 
ATOM   23549 C CD1 . LEU H 1 178 ? -13.025 -60.611 82.951  1.00 24.90  ? 178 LEU H CD1 1 
ATOM   23550 C CD2 . LEU H 1 178 ? -11.788 -62.222 84.460  1.00 24.71  ? 178 LEU H CD2 1 
ATOM   23551 N N   . ILE H 1 179 ? -13.351 -59.133 88.561  1.00 32.25  ? 179 ILE H N   1 
ATOM   23552 C CA  . ILE H 1 179 ? -13.063 -58.015 89.452  1.00 31.43  ? 179 ILE H CA  1 
ATOM   23553 C C   . ILE H 1 179 ? -12.259 -58.447 90.674  1.00 29.86  ? 179 ILE H C   1 
ATOM   23554 O O   . ILE H 1 179 ? -11.631 -57.609 91.325  1.00 28.11  ? 179 ILE H O   1 
ATOM   23555 C CB  . ILE H 1 179 ? -14.386 -57.329 89.862  1.00 30.36  ? 179 ILE H CB  1 
ATOM   23556 C CG1 . ILE H 1 179 ? -14.145 -55.888 90.316  1.00 36.12  ? 179 ILE H CG1 1 
ATOM   23557 C CG2 . ILE H 1 179 ? -15.113 -58.130 90.931  1.00 30.06  ? 179 ILE H CG2 1 
ATOM   23558 C CD1 . ILE H 1 179 ? -14.047 -54.870 89.155  1.00 30.01  ? 179 ILE H CD1 1 
ATOM   23559 N N   . ALA H 1 180 ? -12.240 -59.740 90.996  1.00 31.01  ? 180 ALA H N   1 
ATOM   23560 C CA  . ALA H 1 180 ? -11.677 -60.173 92.275  1.00 31.01  ? 180 ALA H CA  1 
ATOM   23561 C C   . ALA H 1 180 ? -10.155 -60.076 92.332  1.00 39.13  ? 180 ALA H C   1 
ATOM   23562 O O   . ALA H 1 180 ? -9.596  -60.032 93.433  1.00 36.61  ? 180 ALA H O   1 
ATOM   23563 C CB  . ALA H 1 180 ? -12.112 -61.607 92.580  1.00 31.64  ? 180 ALA H CB  1 
ATOM   23564 N N   . GLU H 1 181 ? -9.466  -60.038 91.187  1.00 37.11  ? 181 GLU H N   1 
ATOM   23565 C CA  . GLU H 1 181 ? -8.010  -60.144 91.221  1.00 38.15  ? 181 GLU H CA  1 
ATOM   23566 C C   . GLU H 1 181 ? -7.352  -58.818 91.577  1.00 40.06  ? 181 GLU H C   1 
ATOM   23567 O O   . GLU H 1 181 ? -6.494  -58.760 92.462  1.00 38.55  ? 181 GLU H O   1 
ATOM   23568 C CB  . GLU H 1 181 ? -7.472  -60.648 89.880  1.00 39.77  ? 181 GLU H CB  1 
ATOM   23569 C CG  . GLU H 1 181 ? -5.957  -60.816 89.881  1.00 39.15  ? 181 GLU H CG  1 
ATOM   23570 C CD  . GLU H 1 181 ? -5.490  -61.871 88.904  1.00 53.51  ? 181 GLU H CD  1 
ATOM   23571 O OE1 . GLU H 1 181 ? -6.346  -62.494 88.230  1.00 56.28  ? 181 GLU H OE1 1 
ATOM   23572 O OE2 . GLU H 1 181 ? -4.259  -62.071 88.799  1.00 64.09  ? 181 GLU H OE2 1 
ATOM   23573 N N   . THR H 1 182 ? -7.714  -57.749 90.875  1.00 37.54  ? 182 THR H N   1 
ATOM   23574 C CA  . THR H 1 182 ? -7.106  -56.448 91.084  1.00 33.36  ? 182 THR H CA  1 
ATOM   23575 C C   . THR H 1 182 ? -8.088  -55.404 91.571  1.00 34.20  ? 182 THR H C   1 
ATOM   23576 O O   . THR H 1 182 ? -7.656  -54.314 91.956  1.00 34.98  ? 182 THR H O   1 
ATOM   23577 C CB  . THR H 1 182 ? -6.464  -55.941 89.781  1.00 33.97  ? 182 THR H CB  1 
ATOM   23578 O OG1 . THR H 1 182 ? -7.484  -55.778 88.795  1.00 27.06  ? 182 THR H OG1 1 
ATOM   23579 C CG2 . THR H 1 182 ? -5.424  -56.950 89.261  1.00 29.97  ? 182 THR H CG2 1 
ATOM   23580 N N   . GLY H 1 183 ? -9.384  -55.695 91.566  1.00 30.76  ? 183 GLY H N   1 
ATOM   23581 C CA  . GLY H 1 183 ? -10.378 -54.675 91.806  1.00 36.62  ? 183 GLY H CA  1 
ATOM   23582 C C   . GLY H 1 183 ? -10.654 -53.780 90.617  1.00 39.24  ? 183 GLY H C   1 
ATOM   23583 O O   . GLY H 1 183 ? -11.415 -52.810 90.750  1.00 38.17  ? 183 GLY H O   1 
ATOM   23584 N N   . MET H 1 184 ? -10.061 -54.066 89.460  1.00 35.51  ? 184 MET H N   1 
ATOM   23585 C CA  . MET H 1 184 ? -10.276 -53.270 88.262  1.00 31.43  ? 184 MET H CA  1 
ATOM   23586 C C   . MET H 1 184 ? -10.537 -54.194 87.082  1.00 28.92  ? 184 MET H C   1 
ATOM   23587 O O   . MET H 1 184 ? -9.839  -55.196 86.897  1.00 25.49  ? 184 MET H O   1 
ATOM   23588 C CB  . MET H 1 184 ? -9.080  -52.362 87.985  1.00 31.55  ? 184 MET H CB  1 
ATOM   23589 C CG  . MET H 1 184 ? -8.627  -51.562 89.192  1.00 34.69  ? 184 MET H CG  1 
ATOM   23590 S SD  . MET H 1 184 ? -7.249  -50.504 88.779  1.00 42.42  ? 184 MET H SD  1 
ATOM   23591 C CE  . MET H 1 184 ? -5.982  -51.549 89.461  1.00 44.06  ? 184 MET H CE  1 
ATOM   23592 N N   . VAL H 1 185 ? -11.561 -53.863 86.310  1.00 26.02  ? 185 VAL H N   1 
ATOM   23593 C CA  . VAL H 1 185 ? -11.896 -54.562 85.084  1.00 26.52  ? 185 VAL H CA  1 
ATOM   23594 C C   . VAL H 1 185 ? -11.983 -53.515 83.993  1.00 30.39  ? 185 VAL H C   1 
ATOM   23595 O O   . VAL H 1 185 ? -12.452 -52.397 84.233  1.00 30.37  ? 185 VAL H O   1 
ATOM   23596 C CB  . VAL H 1 185 ? -13.217 -55.339 85.213  1.00 25.18  ? 185 VAL H CB  1 
ATOM   23597 C CG1 . VAL H 1 185 ? -13.864 -55.537 83.853  1.00 26.56  ? 185 VAL H CG1 1 
ATOM   23598 C CG2 . VAL H 1 185 ? -12.967 -56.652 85.886  1.00 28.75  ? 185 VAL H CG2 1 
ATOM   23599 N N   . ILE H 1 186 ? -11.497 -53.854 82.805  1.00 27.49  ? 186 ILE H N   1 
ATOM   23600 C CA  . ILE H 1 186 ? -11.606 -52.967 81.658  1.00 31.89  ? 186 ILE H CA  1 
ATOM   23601 C C   . ILE H 1 186 ? -12.490 -53.643 80.614  1.00 24.72  ? 186 ILE H C   1 
ATOM   23602 O O   . ILE H 1 186 ? -12.361 -54.846 80.370  1.00 27.06  ? 186 ILE H O   1 
ATOM   23603 C CB  . ILE H 1 186 ? -10.220 -52.585 81.101  1.00 27.01  ? 186 ILE H CB  1 
ATOM   23604 C CG1 . ILE H 1 186 ? -10.372 -51.525 80.010  1.00 28.04  ? 186 ILE H CG1 1 
ATOM   23605 C CG2 . ILE H 1 186 ? -9.459  -53.805 80.597  1.00 30.17  ? 186 ILE H CG2 1 
ATOM   23606 C CD1 . ILE H 1 186 ? -9.120  -50.707 79.767  1.00 30.85  ? 186 ILE H CD1 1 
ATOM   23607 N N   . ALA H 1 187 ? -13.430 -52.883 80.056  1.00 24.45  ? 187 ALA H N   1 
ATOM   23608 C CA  . ALA H 1 187 ? -14.322 -53.354 79.002  1.00 28.71  ? 187 ALA H CA  1 
ATOM   23609 C C   . ALA H 1 187 ? -14.095 -52.521 77.743  1.00 33.75  ? 187 ALA H C   1 
ATOM   23610 O O   . ALA H 1 187 ? -14.062 -51.281 77.808  1.00 31.33  ? 187 ALA H O   1 
ATOM   23611 C CB  . ALA H 1 187 ? -15.790 -53.287 79.429  1.00 21.85  ? 187 ALA H CB  1 
ATOM   23612 N N   . LYS H 1 188 ? -13.925 -53.204 76.606  1.00 28.33  ? 188 LYS H N   1 
ATOM   23613 C CA  . LYS H 1 188 ? -13.443 -52.578 75.382  1.00 35.88  ? 188 LYS H CA  1 
ATOM   23614 C C   . LYS H 1 188 ? -14.395 -52.873 74.238  1.00 35.17  ? 188 LYS H C   1 
ATOM   23615 O O   . LYS H 1 188 ? -14.817 -54.020 74.059  1.00 33.46  ? 188 LYS H O   1 
ATOM   23616 C CB  . LYS H 1 188 ? -12.042 -53.078 74.999  1.00 32.92  ? 188 LYS H CB  1 
ATOM   23617 C CG  . LYS H 1 188 ? -10.945 -52.810 76.000  1.00 33.32  ? 188 LYS H CG  1 
ATOM   23618 C CD  . LYS H 1 188 ? -9.586  -53.205 75.408  1.00 34.38  ? 188 LYS H CD  1 
ATOM   23619 C CE  . LYS H 1 188 ? -8.420  -52.810 76.308  1.00 36.94  ? 188 LYS H CE  1 
ATOM   23620 N NZ  . LYS H 1 188 ? -7.163  -52.457 75.547  1.00 40.99  ? 188 LYS H NZ  1 
ATOM   23621 N N   . GLN H 1 189 ? -14.723 -51.834 73.473  1.00 32.55  ? 189 GLN H N   1 
ATOM   23622 C CA  . GLN H 1 189 ? -15.337 -52.000 72.159  1.00 37.70  ? 189 GLN H CA  1 
ATOM   23623 C C   . GLN H 1 189 ? -14.438 -52.823 71.241  1.00 34.93  ? 189 GLN H C   1 
ATOM   23624 O O   . GLN H 1 189 ? -13.232 -52.583 71.152  1.00 32.10  ? 189 GLN H O   1 
ATOM   23625 C CB  . GLN H 1 189 ? -15.575 -50.625 71.548  1.00 37.64  ? 189 GLN H CB  1 
ATOM   23626 C CG  . GLN H 1 189 ? -16.481 -50.603 70.369  1.00 43.80  ? 189 GLN H CG  1 
ATOM   23627 C CD  . GLN H 1 189 ? -16.505 -49.237 69.725  1.00 47.80  ? 189 GLN H CD  1 
ATOM   23628 O OE1 . GLN H 1 189 ? -15.495 -48.515 69.728  1.00 49.65  ? 189 GLN H OE1 1 
ATOM   23629 N NE2 . GLN H 1 189 ? -17.655 -48.867 69.167  1.00 49.73  ? 189 GLN H NE2 1 
ATOM   23630 N N   . ASP H 1 190 ? -15.038 -53.768 70.518  1.00 35.39  ? 190 ASP H N   1 
ATOM   23631 C CA  . ASP H 1 190 ? -14.241 -54.787 69.841  1.00 35.46  ? 190 ASP H CA  1 
ATOM   23632 C C   . ASP H 1 190 ? -13.328 -54.214 68.765  1.00 36.33  ? 190 ASP H C   1 
ATOM   23633 O O   . ASP H 1 190 ? -12.257 -54.775 68.519  1.00 35.68  ? 190 ASP H O   1 
ATOM   23634 C CB  . ASP H 1 190 ? -15.146 -55.854 69.236  1.00 35.28  ? 190 ASP H CB  1 
ATOM   23635 C CG  . ASP H 1 190 ? -14.446 -57.210 69.102  1.00 36.33  ? 190 ASP H CG  1 
ATOM   23636 O OD1 . ASP H 1 190 ? -13.309 -57.364 69.606  1.00 35.42  ? 190 ASP H OD1 1 
ATOM   23637 O OD2 . ASP H 1 190 ? -15.023 -58.126 68.481  1.00 35.37  ? 190 ASP H OD2 1 
ATOM   23638 N N   . ARG H 1 191 ? -13.712 -53.109 68.116  1.00 37.49  ? 191 ARG H N   1 
ATOM   23639 C CA  . ARG H 1 191 ? -12.934 -52.558 67.008  1.00 43.46  ? 191 ARG H CA  1 
ATOM   23640 C C   . ARG H 1 191 ? -12.420 -51.160 67.320  1.00 50.67  ? 191 ARG H C   1 
ATOM   23641 O O   . ARG H 1 191 ? -13.036 -50.413 68.090  1.00 55.77  ? 191 ARG H O   1 
ATOM   23642 C CB  . ARG H 1 191 ? -13.759 -52.494 65.711  1.00 43.57  ? 191 ARG H CB  1 
ATOM   23643 C CG  . ARG H 1 191 ? -13.797 -53.796 64.903  1.00 42.87  ? 191 ARG H CG  1 
ATOM   23644 C CD  . ARG H 1 191 ? -14.805 -53.691 63.756  1.00 48.62  ? 191 ARG H CD  1 
ATOM   23645 N NE  . ARG H 1 191 ? -14.907 -54.900 62.943  1.00 46.25  ? 191 ARG H NE  1 
ATOM   23646 C CZ  . ARG H 1 191 ? -16.044 -55.368 62.446  1.00 47.04  ? 191 ARG H CZ  1 
ATOM   23647 N NH1 . ARG H 1 191 ? -17.208 -54.802 62.730  1.00 51.76  ? 191 ARG H NH1 1 
ATOM   23648 N NH2 . ARG H 1 191 ? -16.014 -56.428 61.644  1.00 45.03  ? 191 ARG H NH2 1 
ATOM   23649 N N   . SER H 1 192 ? -11.286 -50.812 66.690  1.00 52.91  ? 192 SER H N   1 
ATOM   23650 C CA  . SER H 1 192 ? -10.731 -49.451 66.644  1.00 58.16  ? 192 SER H CA  1 
ATOM   23651 C C   . SER H 1 192 ? -10.227 -48.975 68.008  1.00 62.29  ? 192 SER H C   1 
ATOM   23652 O O   . SER H 1 192 ? -9.023  -49.025 68.273  1.00 66.45  ? 192 SER H O   1 
ATOM   23653 C CB  . SER H 1 192 ? -11.771 -48.462 66.070  1.00 58.51  ? 192 SER H CB  1 
ATOM   23654 O OG  . SER H 1 192 ? -11.651 -47.155 66.626  1.00 65.32  ? 192 SER H OG  1 
ATOM   23655 N N   . GLY H 1 193 ? -11.120 -48.482 68.870  1.00 62.76  ? 193 GLY H N   1 
ATOM   23656 C CA  . GLY H 1 193 ? -10.730 -48.141 70.226  1.00 65.06  ? 193 GLY H CA  1 
ATOM   23657 C C   . GLY H 1 193 ? -9.988  -46.826 70.389  1.00 69.98  ? 193 GLY H C   1 
ATOM   23658 O O   . GLY H 1 193 ? -10.593 -45.750 70.300  1.00 73.50  ? 193 GLY H O   1 
ATOM   23659 N N   . GLY H 1 194 ? -8.682  -46.894 70.651  1.00 61.42  ? 194 GLY H N   1 
ATOM   23660 C CA  . GLY H 1 194 ? -7.920  -45.696 70.958  1.00 64.60  ? 194 GLY H CA  1 
ATOM   23661 C C   . GLY H 1 194 ? -8.275  -45.061 72.286  1.00 70.07  ? 194 GLY H C   1 
ATOM   23662 O O   . GLY H 1 194 ? -8.228  -43.831 72.411  1.00 69.68  ? 194 GLY H O   1 
ATOM   23663 N N   . GLY H 1 195 ? -8.638  -45.865 73.281  1.00 63.52  ? 195 GLY H N   1 
ATOM   23664 C CA  . GLY H 1 195 ? -9.047  -45.367 74.588  1.00 62.84  ? 195 GLY H CA  1 
ATOM   23665 C C   . GLY H 1 195 ? -10.490 -44.882 74.693  1.00 63.56  ? 195 GLY H C   1 
ATOM   23666 O O   . GLY H 1 195 ? -11.142 -45.103 75.718  1.00 52.65  ? 195 GLY H O   1 
ATOM   23667 N N   . HIS H 1 196 ? -10.999 -44.220 73.638  1.00 70.36  ? 196 HIS H N   1 
ATOM   23668 C CA  . HIS H 1 196 ? -12.363 -43.691 73.660  1.00 62.56  ? 196 HIS H CA  1 
ATOM   23669 C C   . HIS H 1 196 ? -13.414 -44.795 73.676  1.00 61.26  ? 196 HIS H C   1 
ATOM   23670 O O   . HIS H 1 196 ? -14.539 -44.554 74.128  1.00 54.01  ? 196 HIS H O   1 
ATOM   23671 C CB  . HIS H 1 196 ? -12.633 -42.762 72.461  1.00 66.76  ? 196 HIS H CB  1 
ATOM   23672 C CG  . HIS H 1 196 ? -11.400 -42.196 71.816  1.00 73.42  ? 196 HIS H CG  1 
ATOM   23673 N ND1 . HIS H 1 196 ? -10.403 -41.564 72.531  1.00 79.86  ? 196 HIS H ND1 1 
ATOM   23674 C CD2 . HIS H 1 196 ? -11.025 -42.131 70.514  1.00 80.88  ? 196 HIS H CD2 1 
ATOM   23675 C CE1 . HIS H 1 196 ? -9.458  -41.157 71.701  1.00 85.29  ? 196 HIS H CE1 1 
ATOM   23676 N NE2 . HIS H 1 196 ? -9.810  -41.488 70.470  1.00 86.24  ? 196 HIS H NE2 1 
ATOM   23677 N N   . GLY H 1 197 ? -13.079 -45.991 73.191  1.00 60.82  ? 197 GLY H N   1 
ATOM   23678 C CA  . GLY H 1 197 ? -14.005 -47.107 73.223  1.00 56.25  ? 197 GLY H CA  1 
ATOM   23679 C C   . GLY H 1 197 ? -13.709 -48.111 74.325  1.00 55.76  ? 197 GLY H C   1 
ATOM   23680 O O   . GLY H 1 197 ? -13.878 -49.323 74.127  1.00 47.17  ? 197 GLY H O   1 
ATOM   23681 N N   . ASN H 1 198 ? -13.266 -47.616 75.489  1.00 48.35  ? 198 ASN H N   1 
ATOM   23682 C CA  . ASN H 1 198 ? -12.958 -48.442 76.649  1.00 41.48  ? 198 ASN H CA  1 
ATOM   23683 C C   . ASN H 1 198 ? -13.531 -47.813 77.911  1.00 42.11  ? 198 ASN H C   1 
ATOM   23684 O O   . ASN H 1 198 ? -13.447 -46.598 78.100  1.00 45.49  ? 198 ASN H O   1 
ATOM   23685 C CB  . ASN H 1 198 ? -11.459 -48.610 76.847  1.00 41.88  ? 198 ASN H CB  1 
ATOM   23686 C CG  . ASN H 1 198 ? -10.764 -49.131 75.621  1.00 44.59  ? 198 ASN H CG  1 
ATOM   23687 O OD1 . ASN H 1 198 ? -11.386 -49.715 74.737  1.00 39.41  ? 198 ASN H OD1 1 
ATOM   23688 N ND2 . ASN H 1 198 ? -9.458  -48.917 75.558  1.00 33.83  ? 198 ASN H ND2 1 
ATOM   23689 N N   . ILE H 1 199 ? -14.082 -48.646 78.788  1.00 41.01  ? 199 ILE H N   1 
ATOM   23690 C CA  . ILE H 1 199 ? -14.632 -48.192 80.058  1.00 37.37  ? 199 ILE H CA  1 
ATOM   23691 C C   . ILE H 1 199 ? -14.052 -49.053 81.176  1.00 34.15  ? 199 ILE H C   1 
ATOM   23692 O O   . ILE H 1 199 ? -13.944 -50.277 81.043  1.00 28.03  ? 199 ILE H O   1 
ATOM   23693 C CB  . ILE H 1 199 ? -16.173 -48.248 80.052  1.00 34.18  ? 199 ILE H CB  1 
ATOM   23694 C CG1 . ILE H 1 199 ? -16.734 -47.232 79.046  1.00 34.03  ? 199 ILE H CG1 1 
ATOM   23695 C CG2 . ILE H 1 199 ? -16.715 -48.031 81.461  1.00 30.47  ? 199 ILE H CG2 1 
ATOM   23696 C CD1 . ILE H 1 199 ? -18.170 -47.488 78.583  1.00 37.11  ? 199 ILE H CD1 1 
ATOM   23697 N N   . GLY H 1 200 ? -13.649 -48.409 82.263  1.00 33.32  ? 200 GLY H N   1 
ATOM   23698 C CA  . GLY H 1 200 ? -13.128 -49.107 83.419  1.00 31.90  ? 200 GLY H CA  1 
ATOM   23699 C C   . GLY H 1 200 ? -14.213 -49.350 84.450  1.00 35.00  ? 200 GLY H C   1 
ATOM   23700 O O   . GLY H 1 200 ? -15.216 -48.634 84.504  1.00 29.98  ? 200 GLY H O   1 
ATOM   23701 N N   . ILE H 1 201 ? -14.009 -50.393 85.254  1.00 30.75  ? 201 ILE H N   1 
ATOM   23702 C CA  . ILE H 1 201 ? -14.855 -50.699 86.403  1.00 29.31  ? 201 ILE H CA  1 
ATOM   23703 C C   . ILE H 1 201 ? -13.925 -50.943 87.573  1.00 33.04  ? 201 ILE H C   1 
ATOM   23704 O O   . ILE H 1 201 ? -13.039 -51.803 87.488  1.00 29.50  ? 201 ILE H O   1 
ATOM   23705 C CB  . ILE H 1 201 ? -15.755 -51.920 86.172  1.00 27.79  ? 201 ILE H CB  1 
ATOM   23706 C CG1 . ILE H 1 201 ? -16.852 -51.606 85.175  1.00 29.73  ? 201 ILE H CG1 1 
ATOM   23707 C CG2 . ILE H 1 201 ? -16.395 -52.372 87.471  1.00 29.14  ? 201 ILE H CG2 1 
ATOM   23708 C CD1 . ILE H 1 201 ? -17.655 -52.822 84.831  1.00 33.35  ? 201 ILE H CD1 1 
ATOM   23709 N N   . SER H 1 202 ? -14.119 -50.195 88.661  1.00 33.27  ? 202 SER H N   1 
ATOM   23710 C CA  . SER H 1 202 ? -13.087 -50.081 89.683  1.00 34.56  ? 202 SER H CA  1 
ATOM   23711 C C   . SER H 1 202 ? -13.681 -50.122 91.076  1.00 32.86  ? 202 SER H C   1 
ATOM   23712 O O   . SER H 1 202 ? -14.672 -49.444 91.356  1.00 34.29  ? 202 SER H O   1 
ATOM   23713 C CB  . SER H 1 202 ? -12.299 -48.776 89.523  1.00 34.86  ? 202 SER H CB  1 
ATOM   23714 O OG  . SER H 1 202 ? -11.164 -48.747 90.367  1.00 39.36  ? 202 SER H OG  1 
ATOM   23715 N N   . THR H 1 203 ? -13.049 -50.892 91.956  1.00 35.84  ? 203 THR H N   1 
ATOM   23716 C CA  . THR H 1 203 ? -13.374 -50.790 93.370  1.00 41.18  ? 203 THR H CA  1 
ATOM   23717 C C   . THR H 1 203 ? -12.628 -49.655 94.051  1.00 42.71  ? 203 THR H C   1 
ATOM   23718 O O   . THR H 1 203 ? -12.760 -49.493 95.269  1.00 47.18  ? 203 THR H O   1 
ATOM   23719 C CB  . THR H 1 203 ? -13.073 -52.100 94.100  1.00 35.95  ? 203 THR H CB  1 
ATOM   23720 O OG1 . THR H 1 203 ? -11.662 -52.290 94.172  1.00 41.65  ? 203 THR H OG1 1 
ATOM   23721 C CG2 . THR H 1 203 ? -13.684 -53.271 93.374  1.00 38.19  ? 203 THR H CG2 1 
ATOM   23722 N N   . SER H 1 204 ? -11.861 -48.868 93.308  1.00 37.37  ? 204 SER H N   1 
ATOM   23723 C CA  . SER H 1 204 ? -11.080 -47.805 93.925  1.00 48.44  ? 204 SER H CA  1 
ATOM   23724 C C   . SER H 1 204 ? -11.140 -46.552 93.065  1.00 52.47  ? 204 SER H C   1 
ATOM   23725 O O   . SER H 1 204 ? -10.698 -46.569 91.912  1.00 56.53  ? 204 SER H O   1 
ATOM   23726 C CB  . SER H 1 204 ? -9.622  -48.238 94.137  1.00 53.20  ? 204 SER H CB  1 
ATOM   23727 O OG  . SER H 1 204 ? -9.522  -49.582 94.603  1.00 47.85  ? 204 SER H OG  1 
ATOM   23728 N N   . PRO H 1 205 ? -11.692 -45.452 93.582  1.00 54.22  ? 205 PRO H N   1 
ATOM   23729 C CA  . PRO H 1 205 ? -11.608 -44.190 92.829  1.00 54.77  ? 205 PRO H CA  1 
ATOM   23730 C C   . PRO H 1 205 ? -10.191 -43.669 92.751  1.00 60.91  ? 205 PRO H C   1 
ATOM   23731 O O   . PRO H 1 205 ? -9.789  -43.130 91.711  1.00 62.68  ? 205 PRO H O   1 
ATOM   23732 C CB  . PRO H 1 205 ? -12.525 -43.237 93.605  1.00 55.45  ? 205 PRO H CB  1 
ATOM   23733 C CG  . PRO H 1 205 ? -13.007 -43.988 94.807  1.00 57.50  ? 205 PRO H CG  1 
ATOM   23734 C CD  . PRO H 1 205 ? -12.281 -45.284 94.915  1.00 54.31  ? 205 PRO H CD  1 
ATOM   23735 N N   . GLU H 1 206 ? -9.415  -43.851 93.828  1.00 62.60  ? 206 GLU H N   1 
ATOM   23736 C CA  . GLU H 1 206 ? -7.995  -43.512 93.854  1.00 68.82  ? 206 GLU H CA  1 
ATOM   23737 C C   . GLU H 1 206 ? -7.238  -44.080 92.654  1.00 65.85  ? 206 GLU H C   1 
ATOM   23738 O O   . GLU H 1 206 ? -6.141  -43.605 92.332  1.00 67.57  ? 206 GLU H O   1 
ATOM   23739 C CB  . GLU H 1 206 ? -7.403  -44.022 95.183  1.00 71.81  ? 206 GLU H CB  1 
ATOM   23740 C CG  . GLU H 1 206 ? -5.880  -44.040 95.289  1.00 76.20  ? 206 GLU H CG  1 
ATOM   23741 C CD  . GLU H 1 206 ? -5.263  -45.315 94.719  1.00 83.08  ? 206 GLU H CD  1 
ATOM   23742 O OE1 . GLU H 1 206 ? -5.983  -46.341 94.630  1.00 77.77  ? 206 GLU H OE1 1 
ATOM   23743 O OE2 . GLU H 1 206 ? -4.068  -45.278 94.335  1.00 85.06  ? 206 GLU H OE2 1 
ATOM   23744 N N   . SER H 1 207 ? -7.816  -45.064 91.973  1.00 68.50  ? 207 SER H N   1 
ATOM   23745 C CA  . SER H 1 207 ? -7.115  -45.785 90.924  1.00 60.51  ? 207 SER H CA  1 
ATOM   23746 C C   . SER H 1 207 ? -6.793  -44.884 89.740  1.00 64.16  ? 207 SER H C   1 
ATOM   23747 O O   . SER H 1 207 ? -7.599  -44.037 89.335  1.00 65.71  ? 207 SER H O   1 
ATOM   23748 C CB  . SER H 1 207 ? -7.952  -46.984 90.454  1.00 63.23  ? 207 SER H CB  1 
ATOM   23749 O OG  . SER H 1 207 ? -8.846  -46.663 89.397  1.00 56.53  ? 207 SER H OG  1 
ATOM   23750 N N   . SER H 1 208 ? -5.595  -45.067 89.193  1.00 64.89  ? 208 SER H N   1 
ATOM   23751 C CA  . SER H 1 208 ? -5.248  -44.523 87.890  1.00 59.62  ? 208 SER H CA  1 
ATOM   23752 C C   . SER H 1 208 ? -5.720  -45.518 86.836  1.00 52.26  ? 208 SER H C   1 
ATOM   23753 O O   . SER H 1 208 ? -5.319  -46.686 86.860  1.00 53.15  ? 208 SER H O   1 
ATOM   23754 C CB  . SER H 1 208 ? -3.743  -44.280 87.789  1.00 52.42  ? 208 SER H CB  1 
ATOM   23755 O OG  . SER H 1 208 ? -3.396  -43.743 86.528  1.00 57.18  ? 208 SER H OG  1 
ATOM   23756 N N   . PHE H 1 209 ? -6.577  -45.069 85.919  1.00 48.63  ? 209 PHE H N   1 
ATOM   23757 C CA  . PHE H 1 209 ? -7.126  -45.930 84.871  1.00 48.12  ? 209 PHE H CA  1 
ATOM   23758 C C   . PHE H 1 209 ? -6.789  -45.400 83.477  1.00 44.67  ? 209 PHE H C   1 
ATOM   23759 O O   . PHE H 1 209 ? -7.691  -45.058 82.699  1.00 40.12  ? 209 PHE H O   1 
ATOM   23760 C CB  . PHE H 1 209 ? -8.638  -46.074 85.036  1.00 46.44  ? 209 PHE H CB  1 
ATOM   23761 C CG  . PHE H 1 209 ? -9.128  -47.492 84.933  1.00 42.59  ? 209 PHE H CG  1 
ATOM   23762 C CD1 . PHE H 1 209 ? -8.815  -48.267 83.830  1.00 41.40  ? 209 PHE H CD1 1 
ATOM   23763 C CD2 . PHE H 1 209 ? -9.911  -48.045 85.928  1.00 40.05  ? 209 PHE H CD2 1 
ATOM   23764 C CE1 . PHE H 1 209 ? -9.264  -49.576 83.725  1.00 35.56  ? 209 PHE H CE1 1 
ATOM   23765 C CE2 . PHE H 1 209 ? -10.361 -49.351 85.827  1.00 39.32  ? 209 PHE H CE2 1 
ATOM   23766 C CZ  . PHE H 1 209 ? -10.036 -50.114 84.721  1.00 36.03  ? 209 PHE H CZ  1 
ATOM   23767 N N   . PRO H 1 210 ? -5.501  -45.322 83.125  1.00 40.70  ? 210 PRO H N   1 
ATOM   23768 C CA  . PRO H 1 210 ? -5.143  -44.875 81.772  1.00 44.56  ? 210 PRO H CA  1 
ATOM   23769 C C   . PRO H 1 210 ? -5.680  -45.836 80.724  1.00 43.59  ? 210 PRO H C   1 
ATOM   23770 O O   . PRO H 1 210 ? -5.623  -47.055 80.894  1.00 41.18  ? 210 PRO H O   1 
ATOM   23771 C CB  . PRO H 1 210 ? -3.611  -44.866 81.793  1.00 45.83  ? 210 PRO H CB  1 
ATOM   23772 C CG  . PRO H 1 210 ? -3.251  -44.788 83.243  1.00 45.38  ? 210 PRO H CG  1 
ATOM   23773 C CD  . PRO H 1 210 ? -4.304  -45.570 83.944  1.00 39.03  ? 210 PRO H CD  1 
ATOM   23774 N N   . GLY H 1 211 ? -6.221  -45.273 79.649  1.00 42.99  ? 211 GLY H N   1 
ATOM   23775 C CA  . GLY H 1 211 ? -6.782  -46.053 78.566  1.00 45.36  ? 211 GLY H CA  1 
ATOM   23776 C C   . GLY H 1 211 ? -8.293  -46.164 78.536  1.00 45.59  ? 211 GLY H C   1 
ATOM   23777 O O   . GLY H 1 211 ? -8.811  -47.059 77.862  1.00 45.28  ? 211 GLY H O   1 
ATOM   23778 N N   . THR H 1 212 ? -9.013  -45.290 79.234  1.00 41.59  ? 212 THR H N   1 
ATOM   23779 C CA  . THR H 1 212 ? -10.458 -45.399 79.359  1.00 42.92  ? 212 THR H CA  1 
ATOM   23780 C C   . THR H 1 212 ? -11.063 -44.016 79.212  1.00 44.94  ? 212 THR H C   1 
ATOM   23781 O O   . THR H 1 212 ? -10.424 -43.019 79.539  1.00 48.60  ? 212 THR H O   1 
ATOM   23782 C CB  . THR H 1 212 ? -10.878 -45.964 80.716  1.00 41.05  ? 212 THR H CB  1 
ATOM   23783 O OG1 . THR H 1 212 ? -10.212 -45.235 81.754  1.00 41.35  ? 212 THR H OG1 1 
ATOM   23784 C CG2 . THR H 1 212 ? -10.515 -47.432 80.830  1.00 40.06  ? 212 THR H CG2 1 
ATOM   23785 N N   . ARG H 1 213 ? -12.303 -43.963 78.733  1.00 42.79  ? 213 ARG H N   1 
ATOM   23786 C CA  . ARG H 1 213 ? -13.014 -42.691 78.715  1.00 42.69  ? 213 ARG H CA  1 
ATOM   23787 C C   . ARG H 1 213 ? -13.698 -42.392 80.047  1.00 49.18  ? 213 ARG H C   1 
ATOM   23788 O O   . ARG H 1 213 ? -13.810 -41.221 80.427  1.00 51.42  ? 213 ARG H O   1 
ATOM   23789 C CB  . ARG H 1 213 ? -14.034 -42.664 77.574  1.00 47.39  ? 213 ARG H CB  1 
ATOM   23790 C CG  . ARG H 1 213 ? -15.040 -43.802 77.557  1.00 45.38  ? 213 ARG H CG  1 
ATOM   23791 C CD  . ARG H 1 213 ? -16.260 -43.420 76.723  1.00 44.95  ? 213 ARG H CD  1 
ATOM   23792 N NE  . ARG H 1 213 ? -16.648 -44.473 75.786  1.00 53.00  ? 213 ARG H NE  1 
ATOM   23793 C CZ  . ARG H 1 213 ? -17.899 -44.794 75.481  1.00 47.09  ? 213 ARG H CZ  1 
ATOM   23794 N NH1 . ARG H 1 213 ? -18.927 -44.200 76.065  1.00 49.81  ? 213 ARG H NH1 1 
ATOM   23795 N NH2 . ARG H 1 213 ? -18.125 -45.722 74.555  1.00 43.24  ? 213 ARG H NH2 1 
ATOM   23796 N N   . GLU H 1 214 ? -14.168 -43.417 80.762  1.00 46.57  ? 214 GLU H N   1 
ATOM   23797 C CA  . GLU H 1 214 ? -14.687 -43.221 82.108  1.00 42.89  ? 214 GLU H CA  1 
ATOM   23798 C C   . GLU H 1 214 ? -14.550 -44.512 82.910  1.00 43.26  ? 214 GLU H C   1 
ATOM   23799 O O   . GLU H 1 214 ? -14.327 -45.601 82.363  1.00 38.22  ? 214 GLU H O   1 
ATOM   23800 C CB  . GLU H 1 214 ? -16.145 -42.745 82.102  1.00 37.10  ? 214 GLU H CB  1 
ATOM   23801 C CG  . GLU H 1 214 ? -17.158 -43.728 81.588  1.00 40.43  ? 214 GLU H CG  1 
ATOM   23802 C CD  . GLU H 1 214 ? -18.570 -43.213 81.782  1.00 40.03  ? 214 GLU H CD  1 
ATOM   23803 O OE1 . GLU H 1 214 ? -18.780 -42.468 82.756  1.00 38.29  ? 214 GLU H OE1 1 
ATOM   23804 O OE2 . GLU H 1 214 ? -19.459 -43.537 80.967  1.00 39.17  ? 214 GLU H OE2 1 
ATOM   23805 N N   . VAL H 1 215 ? -14.670 -44.358 84.228  1.00 36.90  ? 215 VAL H N   1 
ATOM   23806 C CA  . VAL H 1 215 ? -14.546 -45.441 85.195  1.00 40.16  ? 215 VAL H CA  1 
ATOM   23807 C C   . VAL H 1 215 ? -15.818 -45.464 86.030  1.00 38.93  ? 215 VAL H C   1 
ATOM   23808 O O   . VAL H 1 215 ? -16.357 -44.411 86.389  1.00 37.04  ? 215 VAL H O   1 
ATOM   23809 C CB  . VAL H 1 215 ? -13.295 -45.274 86.090  1.00 41.04  ? 215 VAL H CB  1 
ATOM   23810 C CG1 . VAL H 1 215 ? -13.125 -46.457 87.028  1.00 37.60  ? 215 VAL H CG1 1 
ATOM   23811 C CG2 . VAL H 1 215 ? -12.048 -45.099 85.245  1.00 35.12  ? 215 VAL H CG2 1 
ATOM   23812 N N   . LEU H 1 216 ? -16.314 -46.661 86.303  1.00 35.98  ? 216 LEU H N   1 
ATOM   23813 C CA  . LEU H 1 216 ? -17.546 -46.861 87.044  1.00 32.38  ? 216 LEU H CA  1 
ATOM   23814 C C   . LEU H 1 216 ? -17.225 -47.522 88.379  1.00 38.61  ? 216 LEU H C   1 
ATOM   23815 O O   . LEU H 1 216 ? -16.331 -48.375 88.463  1.00 37.34  ? 216 LEU H O   1 
ATOM   23816 C CB  . LEU H 1 216 ? -18.516 -47.732 86.246  1.00 34.34  ? 216 LEU H CB  1 
ATOM   23817 C CG  . LEU H 1 216 ? -19.115 -47.195 84.941  1.00 37.61  ? 216 LEU H CG  1 
ATOM   23818 C CD1 . LEU H 1 216 ? -19.853 -48.304 84.159  1.00 28.49  ? 216 LEU H CD1 1 
ATOM   23819 C CD2 . LEU H 1 216 ? -20.051 -46.044 85.247  1.00 34.73  ? 216 LEU H CD2 1 
ATOM   23820 N N   . ALA H 1 217 ? -17.943 -47.111 89.421  1.00 36.79  ? 217 ALA H N   1 
ATOM   23821 C CA  . ALA H 1 217 ? -17.789 -47.727 90.729  1.00 34.01  ? 217 ALA H CA  1 
ATOM   23822 C C   . ALA H 1 217 ? -18.373 -49.130 90.709  1.00 32.84  ? 217 ALA H C   1 
ATOM   23823 O O   . ALA H 1 217 ? -19.481 -49.340 90.207  1.00 28.40  ? 217 ALA H O   1 
ATOM   23824 C CB  . ALA H 1 217 ? -18.481 -46.879 91.792  1.00 39.86  ? 217 ALA H CB  1 
ATOM   23825 N N   . TYR H 1 218 ? -17.622 -50.094 91.237  1.00 30.09  ? 218 TYR H N   1 
ATOM   23826 C CA  . TYR H 1 218 ? -18.080 -51.475 91.294  1.00 35.07  ? 218 TYR H CA  1 
ATOM   23827 C C   . TYR H 1 218 ? -18.898 -51.751 92.552  1.00 33.21  ? 218 TYR H C   1 
ATOM   23828 O O   . TYR H 1 218 ? -18.539 -51.320 93.652  1.00 33.90  ? 218 TYR H O   1 
ATOM   23829 C CB  . TYR H 1 218 ? -16.914 -52.469 91.257  1.00 32.42  ? 218 TYR H CB  1 
ATOM   23830 C CG  . TYR H 1 218 ? -17.459 -53.872 91.341  1.00 31.32  ? 218 TYR H CG  1 
ATOM   23831 C CD1 . TYR H 1 218 ? -18.032 -54.472 90.226  1.00 26.71  ? 218 TYR H CD1 1 
ATOM   23832 C CD2 . TYR H 1 218 ? -17.484 -54.570 92.560  1.00 27.68  ? 218 TYR H CD2 1 
ATOM   23833 C CE1 . TYR H 1 218 ? -18.563 -55.740 90.296  1.00 28.61  ? 218 TYR H CE1 1 
ATOM   23834 C CE2 . TYR H 1 218 ? -18.029 -55.843 92.644  1.00 28.02  ? 218 TYR H CE2 1 
ATOM   23835 C CZ  . TYR H 1 218 ? -18.570 -56.424 91.509  1.00 29.24  ? 218 TYR H CZ  1 
ATOM   23836 O OH  . TYR H 1 218 ? -19.116 -57.690 91.576  1.00 34.45  ? 218 TYR H OH  1 
ATOM   23837 N N   . ALA H 1 219 ? -19.978 -52.508 92.382  1.00 27.22  ? 219 ALA H N   1 
ATOM   23838 C CA  . ALA H 1 219 ? -20.712 -53.101 93.492  1.00 32.43  ? 219 ALA H CA  1 
ATOM   23839 C C   . ALA H 1 219 ? -21.555 -54.239 92.943  1.00 34.20  ? 219 ALA H C   1 
ATOM   23840 O O   . ALA H 1 219 ? -22.206 -54.084 91.905  1.00 35.16  ? 219 ALA H O   1 
ATOM   23841 C CB  . ALA H 1 219 ? -21.609 -52.083 94.215  1.00 26.95  ? 219 ALA H CB  1 
ATOM   23842 N N   . ASN H 1 220 ? -21.542 -55.373 93.647  1.00 35.33  ? 220 ASN H N   1 
ATOM   23843 C CA  . ASN H 1 220 ? -22.395 -56.505 93.305  1.00 32.08  ? 220 ASN H CA  1 
ATOM   23844 C C   . ASN H 1 220 ? -23.806 -56.050 92.959  1.00 33.00  ? 220 ASN H C   1 
ATOM   23845 O O   . ASN H 1 220 ? -24.372 -56.490 91.950  1.00 32.39  ? 220 ASN H O   1 
ATOM   23846 C CB  . ASN H 1 220 ? -22.441 -57.510 94.459  1.00 35.69  ? 220 ASN H CB  1 
ATOM   23847 C CG  . ASN H 1 220 ? -21.142 -58.297 94.620  1.00 40.33  ? 220 ASN H CG  1 
ATOM   23848 O OD1 . ASN H 1 220 ? -20.158 -58.072 93.911  1.00 38.52  ? 220 ASN H OD1 1 
ATOM   23849 N ND2 . ASN H 1 220 ? -21.140 -59.229 95.571  1.00 40.07  ? 220 ASN H ND2 1 
ATOM   23850 N N   . ASP H 1 221 ? -24.381 -55.152 93.766  1.00 29.11  ? 221 ASP H N   1 
ATOM   23851 C CA  . ASP H 1 221 ? -25.754 -54.737 93.518  1.00 30.74  ? 221 ASP H CA  1 
ATOM   23852 C C   . ASP H 1 221 ? -25.872 -53.759 92.352  1.00 33.28  ? 221 ASP H C   1 
ATOM   23853 O O   . ASP H 1 221 ? -26.983 -53.333 92.027  1.00 32.27  ? 221 ASP H O   1 
ATOM   23854 C CB  . ASP H 1 221 ? -26.386 -54.161 94.808  1.00 37.10  ? 221 ASP H CB  1 
ATOM   23855 C CG  . ASP H 1 221 ? -25.788 -52.802 95.248  1.00 37.52  ? 221 ASP H CG  1 
ATOM   23856 O OD1 . ASP H 1 221 ? -25.010 -52.181 94.494  1.00 39.92  ? 221 ASP H OD1 1 
ATOM   23857 O OD2 . ASP H 1 221 ? -26.095 -52.352 96.383  1.00 41.13  ? 221 ASP H OD2 1 
ATOM   23858 N N   . GLN H 1 222 ? -24.757 -53.388 91.723  1.00 40.89  ? 222 GLN H N   1 
ATOM   23859 C CA  . GLN H 1 222 ? -24.764 -52.567 90.518  1.00 40.21  ? 222 GLN H CA  1 
ATOM   23860 C C   . GLN H 1 222 ? -24.503 -53.392 89.262  1.00 36.09  ? 222 GLN H C   1 
ATOM   23861 O O   . GLN H 1 222 ? -24.433 -52.829 88.169  1.00 33.53  ? 222 GLN H O   1 
ATOM   23862 C CB  . GLN H 1 222 ? -23.702 -51.461 90.620  1.00 40.54  ? 222 GLN H CB  1 
ATOM   23863 C CG  . GLN H 1 222 ? -24.078 -50.256 91.458  1.00 37.51  ? 222 GLN H CG  1 
ATOM   23864 C CD  . GLN H 1 222 ? -25.515 -49.852 91.299  1.00 45.09  ? 222 GLN H CD  1 
ATOM   23865 O OE1 . GLN H 1 222 ? -25.991 -49.649 90.183  1.00 53.42  ? 222 GLN H OE1 1 
ATOM   23866 N NE2 . GLN H 1 222 ? -26.226 -49.727 92.419  1.00 49.13  ? 222 GLN H NE2 1 
ATOM   23867 N N   . LEU H 1 223 ? -24.357 -54.711 89.399  1.00 33.47  ? 223 LEU H N   1 
ATOM   23868 C CA  . LEU H 1 223 ? -23.864 -55.515 88.287  1.00 35.70  ? 223 LEU H CA  1 
ATOM   23869 C C   . LEU H 1 223 ? -24.810 -55.454 87.096  1.00 33.59  ? 223 LEU H C   1 
ATOM   23870 O O   . LEU H 1 223 ? -24.357 -55.371 85.950  1.00 30.34  ? 223 LEU H O   1 
ATOM   23871 C CB  . LEU H 1 223 ? -23.640 -56.955 88.740  1.00 29.48  ? 223 LEU H CB  1 
ATOM   23872 C CG  . LEU H 1 223 ? -22.205 -57.254 89.191  1.00 35.86  ? 223 LEU H CG  1 
ATOM   23873 C CD1 . LEU H 1 223 ? -22.096 -58.587 89.938  1.00 35.08  ? 223 LEU H CD1 1 
ATOM   23874 C CD2 . LEU H 1 223 ? -21.239 -57.214 88.015  1.00 31.76  ? 223 LEU H CD2 1 
ATOM   23875 N N   . ASP H 1 224 ? -26.127 -55.472 87.348  1.00 36.29  ? 224 ASP H N   1 
ATOM   23876 C CA  . ASP H 1 224 ? -27.102 -55.384 86.263  1.00 36.93  ? 224 ASP H CA  1 
ATOM   23877 C C   . ASP H 1 224 ? -26.903 -54.108 85.457  1.00 37.90  ? 224 ASP H C   1 
ATOM   23878 O O   . ASP H 1 224 ? -26.747 -54.152 84.231  1.00 39.29  ? 224 ASP H O   1 
ATOM   23879 C CB  . ASP H 1 224 ? -28.529 -55.436 86.813  1.00 31.91  ? 224 ASP H CB  1 
ATOM   23880 C CG  . ASP H 1 224 ? -28.894 -56.796 87.381  1.00 42.92  ? 224 ASP H CG  1 
ATOM   23881 O OD1 . ASP H 1 224 ? -28.187 -57.785 87.100  1.00 41.18  ? 224 ASP H OD1 1 
ATOM   23882 O OD2 . ASP H 1 224 ? -29.898 -56.871 88.126  1.00 46.77  ? 224 ASP H OD2 1 
ATOM   23883 N N   . THR H 1 225 ? -26.917 -52.957 86.142  1.00 36.88  ? 225 THR H N   1 
ATOM   23884 C CA  . THR H 1 225 ? -26.725 -51.670 85.483  1.00 37.30  ? 225 THR H CA  1 
ATOM   23885 C C   . THR H 1 225 ? -25.401 -51.628 84.739  1.00 37.99  ? 225 THR H C   1 
ATOM   23886 O O   . THR H 1 225 ? -25.355 -51.271 83.556  1.00 33.93  ? 225 THR H O   1 
ATOM   23887 C CB  . THR H 1 225 ? -26.788 -50.537 86.512  1.00 36.82  ? 225 THR H CB  1 
ATOM   23888 O OG1 . THR H 1 225 ? -28.083 -50.522 87.109  1.00 41.36  ? 225 THR H OG1 1 
ATOM   23889 C CG2 . THR H 1 225 ? -26.519 -49.180 85.849  1.00 29.35  ? 225 THR H CG2 1 
ATOM   23890 N N   . LEU H 1 226 ? -24.311 -51.979 85.430  1.00 33.85  ? 226 LEU H N   1 
ATOM   23891 C CA  . LEU H 1 226 ? -22.994 -52.066 84.812  1.00 39.62  ? 226 LEU H CA  1 
ATOM   23892 C C   . LEU H 1 226 ? -23.045 -52.778 83.466  1.00 31.45  ? 226 LEU H C   1 
ATOM   23893 O O   . LEU H 1 226 ? -22.636 -52.226 82.438  1.00 31.87  ? 226 LEU H O   1 
ATOM   23894 C CB  . LEU H 1 226 ? -22.034 -52.804 85.752  1.00 34.44  ? 226 LEU H CB  1 
ATOM   23895 C CG  . LEU H 1 226 ? -21.172 -51.925 86.645  1.00 39.23  ? 226 LEU H CG  1 
ATOM   23896 C CD1 . LEU H 1 226 ? -21.953 -50.720 87.169  1.00 43.02  ? 226 LEU H CD1 1 
ATOM   23897 C CD2 . LEU H 1 226 ? -20.592 -52.768 87.772  1.00 34.50  ? 226 LEU H CD2 1 
ATOM   23898 N N   . ALA H 1 227 ? -23.558 -54.012 83.480  1.00 28.98  ? 227 ALA H N   1 
ATOM   23899 C CA  . ALA H 1 227 ? -23.619 -54.833 82.275  1.00 31.56  ? 227 ALA H CA  1 
ATOM   23900 C C   . ALA H 1 227 ? -24.425 -54.148 81.182  1.00 35.06  ? 227 ALA H C   1 
ATOM   23901 O O   . ALA H 1 227 ? -23.956 -54.012 80.050  1.00 35.49  ? 227 ALA H O   1 
ATOM   23902 C CB  . ALA H 1 227 ? -24.217 -56.193 82.600  1.00 27.70  ? 227 ALA H CB  1 
ATOM   23903 N N   . ASP H 1 228 ? -25.643 -53.703 81.504  1.00 37.98  ? 228 ASP H N   1 
ATOM   23904 C CA  . ASP H 1 228 ? -26.444 -52.982 80.516  1.00 38.05  ? 228 ASP H CA  1 
ATOM   23905 C C   . ASP H 1 228 ? -25.695 -51.763 79.995  1.00 37.57  ? 228 ASP H C   1 
ATOM   23906 O O   . ASP H 1 228 ? -25.639 -51.526 78.782  1.00 36.13  ? 228 ASP H O   1 
ATOM   23907 C CB  . ASP H 1 228 ? -27.781 -52.564 81.125  1.00 31.17  ? 228 ASP H CB  1 
ATOM   23908 C CG  . ASP H 1 228 ? -28.714 -53.740 81.341  1.00 47.37  ? 228 ASP H CG  1 
ATOM   23909 O OD1 . ASP H 1 228 ? -28.463 -54.825 80.772  1.00 42.50  ? 228 ASP H OD1 1 
ATOM   23910 O OD2 . ASP H 1 228 ? -29.715 -53.575 82.069  1.00 56.03  ? 228 ASP H OD2 1 
ATOM   23911 N N   . THR H 1 229 ? -25.112 -50.984 80.914  1.00 36.13  ? 229 THR H N   1 
ATOM   23912 C CA  . THR H 1 229 ? -24.358 -49.777 80.572  1.00 37.52  ? 229 THR H CA  1 
ATOM   23913 C C   . THR H 1 229 ? -23.209 -50.095 79.624  1.00 36.73  ? 229 THR H C   1 
ATOM   23914 O O   . THR H 1 229 ? -23.047 -49.450 78.584  1.00 37.12  ? 229 THR H O   1 
ATOM   23915 C CB  . THR H 1 229 ? -23.812 -49.134 81.857  1.00 40.40  ? 229 THR H CB  1 
ATOM   23916 O OG1 . THR H 1 229 ? -24.884 -48.868 82.782  1.00 42.77  ? 229 THR H OG1 1 
ATOM   23917 C CG2 . THR H 1 229 ? -23.038 -47.854 81.561  1.00 36.72  ? 229 THR H CG2 1 
ATOM   23918 N N   . LEU H 1 230 ? -22.375 -51.068 79.991  1.00 36.29  ? 230 LEU H N   1 
ATOM   23919 C CA  . LEU H 1 230 ? -21.264 -51.444 79.126  1.00 34.75  ? 230 LEU H CA  1 
ATOM   23920 C C   . LEU H 1 230 ? -21.770 -51.935 77.779  1.00 34.72  ? 230 LEU H C   1 
ATOM   23921 O O   . LEU H 1 230 ? -21.299 -51.491 76.726  1.00 31.78  ? 230 LEU H O   1 
ATOM   23922 C CB  . LEU H 1 230 ? -20.412 -52.518 79.789  1.00 35.79  ? 230 LEU H CB  1 
ATOM   23923 C CG  . LEU H 1 230 ? -19.611 -52.101 81.022  1.00 43.97  ? 230 LEU H CG  1 
ATOM   23924 C CD1 . LEU H 1 230 ? -18.661 -53.222 81.408  1.00 35.88  ? 230 LEU H CD1 1 
ATOM   23925 C CD2 . LEU H 1 230 ? -18.865 -50.818 80.773  1.00 40.08  ? 230 LEU H CD2 1 
ATOM   23926 N N   . TRP H 1 231 ? -22.756 -52.833 77.791  1.00 31.68  ? 231 TRP H N   1 
ATOM   23927 C CA  . TRP H 1 231 ? -23.203 -53.423 76.535  1.00 33.89  ? 231 TRP H CA  1 
ATOM   23928 C C   . TRP H 1 231 ? -23.824 -52.381 75.625  1.00 36.18  ? 231 TRP H C   1 
ATOM   23929 O O   . TRP H 1 231 ? -23.598 -52.402 74.410  1.00 38.32  ? 231 TRP H O   1 
ATOM   23930 C CB  . TRP H 1 231 ? -24.192 -54.566 76.784  1.00 32.07  ? 231 TRP H CB  1 
ATOM   23931 C CG  . TRP H 1 231 ? -24.614 -55.256 75.507  1.00 35.91  ? 231 TRP H CG  1 
ATOM   23932 C CD1 . TRP H 1 231 ? -25.758 -55.029 74.783  1.00 33.34  ? 231 TRP H CD1 1 
ATOM   23933 C CD2 . TRP H 1 231 ? -23.888 -56.275 74.797  1.00 26.91  ? 231 TRP H CD2 1 
ATOM   23934 N NE1 . TRP H 1 231 ? -25.781 -55.835 73.673  1.00 24.23  ? 231 TRP H NE1 1 
ATOM   23935 C CE2 . TRP H 1 231 ? -24.647 -56.611 73.661  1.00 31.25  ? 231 TRP H CE2 1 
ATOM   23936 C CE3 . TRP H 1 231 ? -22.661 -56.913 75.003  1.00 28.02  ? 231 TRP H CE3 1 
ATOM   23937 C CZ2 . TRP H 1 231 ? -24.226 -57.573 72.745  1.00 28.80  ? 231 TRP H CZ2 1 
ATOM   23938 C CZ3 . TRP H 1 231 ? -22.248 -57.869 74.094  1.00 32.03  ? 231 TRP H CZ3 1 
ATOM   23939 C CH2 . TRP H 1 231 ? -23.028 -58.192 72.980  1.00 30.36  ? 231 TRP H CH2 1 
ATOM   23940 N N   . SER H 1 232 ? -24.617 -51.463 76.180  1.00 37.57  ? 232 SER H N   1 
ATOM   23941 C CA  . SER H 1 232 ? -25.281 -50.496 75.310  1.00 39.53  ? 232 SER H CA  1 
ATOM   23942 C C   . SER H 1 232 ? -24.280 -49.502 74.734  1.00 38.01  ? 232 SER H C   1 
ATOM   23943 O O   . SER H 1 232 ? -24.299 -49.219 73.530  1.00 42.45  ? 232 SER H O   1 
ATOM   23944 C CB  . SER H 1 232 ? -26.401 -49.782 76.064  1.00 35.47  ? 232 SER H CB  1 
ATOM   23945 O OG  . SER H 1 232 ? -26.055 -49.596 77.424  1.00 47.42  ? 232 SER H OG  1 
ATOM   23946 N N   . GLN H 1 233 ? -23.361 -49.005 75.564  1.00 35.80  ? 233 GLN H N   1 
ATOM   23947 C CA  . GLN H 1 233 ? -22.411 -47.999 75.105  1.00 37.16  ? 233 GLN H CA  1 
ATOM   23948 C C   . GLN H 1 233 ? -21.331 -48.559 74.174  1.00 36.48  ? 233 GLN H C   1 
ATOM   23949 O O   . GLN H 1 233 ? -20.687 -47.787 73.457  1.00 33.47  ? 233 GLN H O   1 
ATOM   23950 C CB  . GLN H 1 233 ? -21.756 -47.338 76.318  1.00 41.59  ? 233 GLN H CB  1 
ATOM   23951 C CG  . GLN H 1 233 ? -22.209 -45.904 76.613  1.00 41.58  ? 233 GLN H CG  1 
ATOM   23952 C CD  . GLN H 1 233 ? -21.528 -45.333 77.853  1.00 47.04  ? 233 GLN H CD  1 
ATOM   23953 O OE1 . GLN H 1 233 ? -20.657 -44.464 77.761  1.00 48.19  ? 233 GLN H OE1 1 
ATOM   23954 N NE2 . GLN H 1 233 ? -21.913 -45.836 79.021  1.00 50.05  ? 233 GLN H NE2 1 
ATOM   23955 N N   . LEU H 1 234 ? -21.097 -49.868 74.175  1.00 38.84  ? 234 LEU H N   1 
ATOM   23956 C CA  . LEU H 1 234 ? -19.916 -50.421 73.524  1.00 38.66  ? 234 LEU H CA  1 
ATOM   23957 C C   . LEU H 1 234 ? -20.212 -51.383 72.379  1.00 38.50  ? 234 LEU H C   1 
ATOM   23958 O O   . LEU H 1 234 ? -19.262 -51.911 71.793  1.00 35.00  ? 234 LEU H O   1 
ATOM   23959 C CB  . LEU H 1 234 ? -19.014 -51.122 74.558  1.00 34.07  ? 234 LEU H CB  1 
ATOM   23960 C CG  . LEU H 1 234 ? -18.307 -50.256 75.606  1.00 38.43  ? 234 LEU H CG  1 
ATOM   23961 C CD1 . LEU H 1 234 ? -17.347 -51.063 76.480  1.00 31.88  ? 234 LEU H CD1 1 
ATOM   23962 C CD2 . LEU H 1 234 ? -17.572 -49.077 74.946  1.00 35.63  ? 234 LEU H CD2 1 
ATOM   23963 N N   . THR H 1 235 ? -21.481 -51.600 72.017  1.00 39.69  ? 235 THR H N   1 
ATOM   23964 C CA  . THR H 1 235 ? -21.844 -52.400 70.851  1.00 37.60  ? 235 THR H CA  1 
ATOM   23965 C C   . THR H 1 235 ? -22.748 -51.611 69.913  1.00 39.24  ? 235 THR H C   1 
ATOM   23966 O O   . THR H 1 235 ? -23.507 -50.741 70.346  1.00 38.37  ? 235 THR H O   1 
ATOM   23967 C CB  . THR H 1 235 ? -22.572 -53.678 71.234  1.00 33.14  ? 235 THR H CB  1 
ATOM   23968 O OG1 . THR H 1 235 ? -23.746 -53.346 71.980  1.00 30.48  ? 235 THR H OG1 1 
ATOM   23969 C CG2 . THR H 1 235 ? -21.671 -54.577 72.063  1.00 35.64  ? 235 THR H CG2 1 
ATOM   23970 N N   . ASP H 1 236 ? -22.672 -51.963 68.627  1.00 39.10  ? 236 ASP H N   1 
ATOM   23971 C CA  . ASP H 1 236 ? -23.495 -51.400 67.553  1.00 43.15  ? 236 ASP H CA  1 
ATOM   23972 C C   . ASP H 1 236 ? -23.826 -52.527 66.569  1.00 47.71  ? 236 ASP H C   1 
ATOM   23973 O O   . ASP H 1 236 ? -23.606 -53.711 66.853  1.00 41.86  ? 236 ASP H O   1 
ATOM   23974 C CB  . ASP H 1 236 ? -22.798 -50.206 66.873  1.00 39.84  ? 236 ASP H CB  1 
ATOM   23975 C CG  . ASP H 1 236 ? -21.418 -50.560 66.250  1.00 48.95  ? 236 ASP H CG  1 
ATOM   23976 O OD1 . ASP H 1 236 ? -21.025 -51.746 66.125  1.00 45.50  ? 236 ASP H OD1 1 
ATOM   23977 O OD2 . ASP H 1 236 ? -20.709 -49.607 65.871  1.00 55.98  ? 236 ASP H OD2 1 
ATOM   23978 N N   . THR H 1 237 ? -24.349 -52.156 65.394  1.00 39.07  ? 237 THR H N   1 
ATOM   23979 C CA  . THR H 1 237 ? -24.807 -53.163 64.438  1.00 47.91  ? 237 THR H CA  1 
ATOM   23980 C C   . THR H 1 237 ? -23.662 -54.048 63.948  1.00 45.74  ? 237 THR H C   1 
ATOM   23981 O O   . THR H 1 237 ? -23.847 -55.254 63.753  1.00 48.78  ? 237 THR H O   1 
ATOM   23982 C CB  . THR H 1 237 ? -25.504 -52.496 63.247  1.00 46.65  ? 237 THR H CB  1 
ATOM   23983 O OG1 . THR H 1 237 ? -26.339 -51.434 63.716  1.00 53.09  ? 237 THR H OG1 1 
ATOM   23984 C CG2 . THR H 1 237 ? -26.375 -53.505 62.495  1.00 41.65  ? 237 THR H CG2 1 
ATOM   23985 N N   . GLN H 1 238 ? -22.471 -53.476 63.749  1.00 47.01  ? 238 GLN H N   1 
ATOM   23986 C CA  . GLN H 1 238 ? -21.372 -54.239 63.159  1.00 49.52  ? 238 GLN H CA  1 
ATOM   23987 C C   . GLN H 1 238 ? -20.649 -55.124 64.167  1.00 46.56  ? 238 GLN H C   1 
ATOM   23988 O O   . GLN H 1 238 ? -20.046 -56.124 63.767  1.00 48.50  ? 238 GLN H O   1 
ATOM   23989 C CB  . GLN H 1 238 ? -20.344 -53.304 62.517  1.00 52.59  ? 238 GLN H CB  1 
ATOM   23990 C CG  . GLN H 1 238 ? -20.913 -52.223 61.610  1.00 60.59  ? 238 GLN H CG  1 
ATOM   23991 C CD  . GLN H 1 238 ? -20.053 -50.963 61.594  1.00 66.36  ? 238 GLN H CD  1 
ATOM   23992 O OE1 . GLN H 1 238 ? -19.571 -50.505 62.639  1.00 63.60  ? 238 GLN H OE1 1 
ATOM   23993 N NE2 . GLN H 1 238 ? -19.851 -50.399 60.402  1.00 65.73  ? 238 GLN H NE2 1 
ATOM   23994 N N   . ASN H 1 239 ? -20.656 -54.760 65.453  1.00 47.13  ? 239 ASN H N   1 
ATOM   23995 C CA  . ASN H 1 239 ? -19.907 -55.475 66.486  1.00 48.75  ? 239 ASN H CA  1 
ATOM   23996 C C   . ASN H 1 239 ? -20.871 -55.906 67.577  1.00 43.51  ? 239 ASN H C   1 
ATOM   23997 O O   . ASN H 1 239 ? -21.413 -55.064 68.299  1.00 43.75  ? 239 ASN H O   1 
ATOM   23998 C CB  . ASN H 1 239 ? -18.789 -54.631 67.104  1.00 48.20  ? 239 ASN H CB  1 
ATOM   23999 C CG  . ASN H 1 239 ? -18.133 -53.691 66.124  1.00 53.33  ? 239 ASN H CG  1 
ATOM   24000 O OD1 . ASN H 1 239 ? -16.972 -53.877 65.764  1.00 49.16  ? 239 ASN H OD1 1 
ATOM   24001 N ND2 . ASN H 1 239 ? -18.853 -52.643 65.728  1.00 52.45  ? 239 ASN H ND2 1 
ATOM   24002 N N   . GLN H 1 240 ? -21.064 -57.214 67.713  1.00 44.08  ? 240 GLN H N   1 
ATOM   24003 C CA  . GLN H 1 240 ? -21.830 -57.764 68.820  1.00 40.71  ? 240 GLN H CA  1 
ATOM   24004 C C   . GLN H 1 240 ? -20.937 -58.500 69.813  1.00 40.73  ? 240 GLN H C   1 
ATOM   24005 O O   . GLN H 1 240 ? -21.409 -59.377 70.546  1.00 44.60  ? 240 GLN H O   1 
ATOM   24006 C CB  . GLN H 1 240 ? -22.946 -58.664 68.292  1.00 42.47  ? 240 GLN H CB  1 
ATOM   24007 C CG  . GLN H 1 240 ? -23.927 -57.923 67.386  1.00 39.53  ? 240 GLN H CG  1 
ATOM   24008 C CD  . GLN H 1 240 ? -24.948 -57.129 68.193  1.00 45.42  ? 240 GLN H CD  1 
ATOM   24009 O OE1 . GLN H 1 240 ? -25.794 -57.703 68.880  1.00 43.57  ? 240 GLN H OE1 1 
ATOM   24010 N NE2 . GLN H 1 240 ? -24.860 -55.809 68.127  1.00 37.89  ? 240 GLN H NE2 1 
ATOM   24011 N N   . PHE H 1 241 ? -19.653 -58.164 69.847  1.00 38.73  ? 241 PHE H N   1 
ATOM   24012 C CA  . PHE H 1 241 ? -18.754 -58.642 70.881  1.00 31.19  ? 241 PHE H CA  1 
ATOM   24013 C C   . PHE H 1 241 ? -18.310 -57.465 71.728  1.00 32.20  ? 241 PHE H C   1 
ATOM   24014 O O   . PHE H 1 241 ? -18.159 -56.343 71.238  1.00 33.35  ? 241 PHE H O   1 
ATOM   24015 C CB  . PHE H 1 241 ? -17.514 -59.339 70.302  1.00 31.91  ? 241 PHE H CB  1 
ATOM   24016 C CG  . PHE H 1 241 ? -17.800 -60.675 69.679  1.00 36.52  ? 241 PHE H CG  1 
ATOM   24017 C CD1 . PHE H 1 241 ? -18.599 -61.612 70.329  1.00 33.95  ? 241 PHE H CD1 1 
ATOM   24018 C CD2 . PHE H 1 241 ? -17.266 -61.001 68.440  1.00 38.47  ? 241 PHE H CD2 1 
ATOM   24019 C CE1 . PHE H 1 241 ? -18.865 -62.846 69.738  1.00 36.83  ? 241 PHE H CE1 1 
ATOM   24020 C CE2 . PHE H 1 241 ? -17.528 -62.233 67.849  1.00 38.34  ? 241 PHE H CE2 1 
ATOM   24021 C CZ  . PHE H 1 241 ? -18.328 -63.160 68.499  1.00 32.38  ? 241 PHE H CZ  1 
ATOM   24022 N N   . ILE H 1 242 ? -18.100 -57.746 73.005  1.00 33.54  ? 242 ILE H N   1 
ATOM   24023 C CA  . ILE H 1 242 ? -17.412 -56.856 73.925  1.00 28.98  ? 242 ILE H CA  1 
ATOM   24024 C C   . ILE H 1 242 ? -16.286 -57.660 74.551  1.00 24.99  ? 242 ILE H C   1 
ATOM   24025 O O   . ILE H 1 242 ? -16.442 -58.859 74.793  1.00 28.59  ? 242 ILE H O   1 
ATOM   24026 C CB  . ILE H 1 242 ? -18.399 -56.303 74.980  1.00 31.21  ? 242 ILE H CB  1 
ATOM   24027 C CG1 . ILE H 1 242 ? -19.190 -55.176 74.338  1.00 34.57  ? 242 ILE H CG1 1 
ATOM   24028 C CG2 . ILE H 1 242 ? -17.715 -55.771 76.210  1.00 27.07  ? 242 ILE H CG2 1 
ATOM   24029 C CD1 . ILE H 1 242 ? -18.291 -54.289 73.525  1.00 35.84  ? 242 ILE H CD1 1 
ATOM   24030 N N   . THR H 1 243 ? -15.145 -57.024 74.779  1.00 24.67  ? 243 THR H N   1 
ATOM   24031 C CA  . THR H 1 243 ? -14.047 -57.652 75.506  1.00 27.51  ? 243 THR H CA  1 
ATOM   24032 C C   . THR H 1 243 ? -14.075 -57.166 76.955  1.00 31.25  ? 243 THR H C   1 
ATOM   24033 O O   . THR H 1 243 ? -14.257 -55.966 77.207  1.00 26.88  ? 243 THR H O   1 
ATOM   24034 C CB  . THR H 1 243 ? -12.708 -57.341 74.832  1.00 32.05  ? 243 THR H CB  1 
ATOM   24035 O OG1 . THR H 1 243 ? -12.571 -58.173 73.665  1.00 34.98  ? 243 THR H OG1 1 
ATOM   24036 C CG2 . THR H 1 243 ? -11.583 -57.683 75.723  1.00 30.38  ? 243 THR H CG2 1 
ATOM   24037 N N   . VAL H 1 244 ? -13.959 -58.112 77.899  1.00 26.05  ? 244 VAL H N   1 
ATOM   24038 C CA  . VAL H 1 244 ? -14.020 -57.850 79.339  1.00 26.46  ? 244 VAL H CA  1 
ATOM   24039 C C   . VAL H 1 244 ? -12.829 -58.537 79.987  1.00 27.16  ? 244 VAL H C   1 
ATOM   24040 O O   . VAL H 1 244 ? -12.736 -59.769 79.939  1.00 23.20  ? 244 VAL H O   1 
ATOM   24041 C CB  . VAL H 1 244 ? -15.320 -58.370 79.969  1.00 20.40  ? 244 VAL H CB  1 
ATOM   24042 C CG1 . VAL H 1 244 ? -15.334 -58.081 81.465  1.00 28.20  ? 244 VAL H CG1 1 
ATOM   24043 C CG2 . VAL H 1 244 ? -16.536 -57.766 79.274  1.00 28.11  ? 244 VAL H CG2 1 
ATOM   24044 N N   . GLU H 1 245 ? -11.934 -57.750 80.604  1.00 23.16  ? 245 GLU H N   1 
ATOM   24045 C CA  . GLU H 1 245 ? -10.650 -58.257 81.080  1.00 28.29  ? 245 GLU H CA  1 
ATOM   24046 C C   . GLU H 1 245 ? -10.260 -57.676 82.438  1.00 25.50  ? 245 GLU H C   1 
ATOM   24047 O O   . GLU H 1 245 ? -10.515 -56.509 82.744  1.00 23.78  ? 245 GLU H O   1 
ATOM   24048 C CB  . GLU H 1 245 ? -9.505  -57.934 80.089  1.00 27.71  ? 245 GLU H CB  1 
ATOM   24049 C CG  . GLU H 1 245 ? -9.950  -57.905 78.656  1.00 34.18  ? 245 GLU H CG  1 
ATOM   24050 C CD  . GLU H 1 245 ? -8.834  -57.611 77.656  1.00 37.44  ? 245 GLU H CD  1 
ATOM   24051 O OE1 . GLU H 1 245 ? -8.233  -56.510 77.728  1.00 45.49  ? 245 GLU H OE1 1 
ATOM   24052 O OE2 . GLU H 1 245 ? -8.598  -58.472 76.770  1.00 29.39  ? 245 GLU H OE2 1 
ATOM   24053 N N   . THR H 1 246 ? -9.541  -58.483 83.208  1.00 22.46  ? 246 THR H N   1 
ATOM   24054 C CA  . THR H 1 246 ? -8.858  -57.974 84.390  1.00 25.65  ? 246 THR H CA  1 
ATOM   24055 C C   . THR H 1 246 ? -7.823  -56.930 83.999  1.00 26.06  ? 246 THR H C   1 
ATOM   24056 O O   . THR H 1 246 ? -7.061  -57.116 83.051  1.00 26.28  ? 246 THR H O   1 
ATOM   24057 C CB  . THR H 1 246 ? -8.180  -59.126 85.131  1.00 27.72  ? 246 THR H CB  1 
ATOM   24058 O OG1 . THR H 1 246 ? -9.183  -60.049 85.568  1.00 29.34  ? 246 THR H OG1 1 
ATOM   24059 C CG2 . THR H 1 246 ? -7.374  -58.617 86.336  1.00 27.00  ? 246 THR H CG2 1 
ATOM   24060 N N   . TYR H 1 247 ? -7.772  -55.840 84.755  1.00 28.95  ? 247 TYR H N   1 
ATOM   24061 C CA  . TYR H 1 247 ? -6.868  -54.734 84.477  1.00 23.26  ? 247 TYR H CA  1 
ATOM   24062 C C   . TYR H 1 247 ? -5.796  -54.670 85.554  1.00 34.09  ? 247 TYR H C   1 
ATOM   24063 O O   . TYR H 1 247 ? -6.115  -54.499 86.735  1.00 31.38  ? 247 TYR H O   1 
ATOM   24064 C CB  . TYR H 1 247 ? -7.643  -53.427 84.419  1.00 26.99  ? 247 TYR H CB  1 
ATOM   24065 C CG  . TYR H 1 247 ? -6.800  -52.211 84.112  1.00 25.57  ? 247 TYR H CG  1 
ATOM   24066 C CD1 . TYR H 1 247 ? -6.140  -51.526 85.126  1.00 30.03  ? 247 TYR H CD1 1 
ATOM   24067 C CD2 . TYR H 1 247 ? -6.691  -51.739 82.827  1.00 23.13  ? 247 TYR H CD2 1 
ATOM   24068 C CE1 . TYR H 1 247 ? -5.388  -50.404 84.854  1.00 36.58  ? 247 TYR H CE1 1 
ATOM   24069 C CE2 . TYR H 1 247 ? -5.946  -50.625 82.534  1.00 31.37  ? 247 TYR H CE2 1 
ATOM   24070 C CZ  . TYR H 1 247 ? -5.297  -49.954 83.549  1.00 39.38  ? 247 TYR H CZ  1 
ATOM   24071 O OH  . TYR H 1 247 ? -4.560  -48.834 83.256  1.00 41.11  ? 247 TYR H OH  1 
ATOM   24072 N N   . HIS H 1 248 ? -4.529  -54.768 85.150  1.00 34.78  ? 248 HIS H N   1 
ATOM   24073 C CA  . HIS H 1 248 ? -3.416  -54.745 86.088  1.00 33.97  ? 248 HIS H CA  1 
ATOM   24074 C C   . HIS H 1 248 ? -2.783  -53.360 86.141  1.00 34.12  ? 248 HIS H C   1 
ATOM   24075 O O   . HIS H 1 248 ? -2.617  -52.707 85.108  1.00 37.94  ? 248 HIS H O   1 
ATOM   24076 C CB  . HIS H 1 248 ? -2.372  -55.792 85.705  1.00 32.58  ? 248 HIS H CB  1 
ATOM   24077 C CG  . HIS H 1 248 ? -2.884  -57.196 85.786  1.00 33.87  ? 248 HIS H CG  1 
ATOM   24078 N ND1 . HIS H 1 248 ? -2.649  -58.012 86.870  1.00 32.85  ? 248 HIS H ND1 1 
ATOM   24079 C CD2 . HIS H 1 248 ? -3.635  -57.921 84.924  1.00 32.04  ? 248 HIS H CD2 1 
ATOM   24080 C CE1 . HIS H 1 248 ? -3.227  -59.183 86.668  1.00 39.17  ? 248 HIS H CE1 1 
ATOM   24081 N NE2 . HIS H 1 248 ? -3.834  -59.153 85.496  1.00 28.79  ? 248 HIS H NE2 1 
ATOM   24082 N N   . ARG H 1 249 ? -2.459  -52.906 87.357  1.00 32.87  ? 249 ARG H N   1 
ATOM   24083 C CA  . ARG H 1 249 ? -1.573  -51.757 87.529  1.00 39.28  ? 249 ARG H CA  1 
ATOM   24084 C C   . ARG H 1 249 ? -0.222  -52.072 86.921  1.00 41.30  ? 249 ARG H C   1 
ATOM   24085 O O   . ARG H 1 249 ? 0.415   -53.058 87.304  1.00 46.29  ? 249 ARG H O   1 
ATOM   24086 C CB  . ARG H 1 249 ? -1.364  -51.429 89.003  1.00 41.74  ? 249 ARG H CB  1 
ATOM   24087 C CG  . ARG H 1 249 ? -2.577  -51.378 89.852  1.00 49.06  ? 249 ARG H CG  1 
ATOM   24088 C CD  . ARG H 1 249 ? -2.374  -50.325 90.886  1.00 54.03  ? 249 ARG H CD  1 
ATOM   24089 N NE  . ARG H 1 249 ? -3.632  -49.664 91.158  1.00 60.36  ? 249 ARG H NE  1 
ATOM   24090 C CZ  . ARG H 1 249 ? -4.114  -48.677 90.419  1.00 62.37  ? 249 ARG H CZ  1 
ATOM   24091 N NH1 . ARG H 1 249 ? -3.525  -48.294 89.296  1.00 55.31  ? 249 ARG H NH1 1 
ATOM   24092 N NH2 . ARG H 1 249 ? -5.218  -48.067 90.813  1.00 65.42  ? 249 ARG H NH2 1 
ATOM   24093 N N   . ALA H 1 250 ? 0.239   -51.216 86.020  1.00 43.66  ? 250 ALA H N   1 
ATOM   24094 C CA  . ALA H 1 250 ? 1.438   -51.479 85.238  1.00 46.66  ? 250 ALA H CA  1 
ATOM   24095 C C   . ALA H 1 250 ? 2.574   -50.594 85.721  1.00 49.33  ? 250 ALA H C   1 
ATOM   24096 O O   . ALA H 1 250 ? 2.383   -49.393 85.927  1.00 51.54  ? 250 ALA H O   1 
ATOM   24097 C CB  . ALA H 1 250 ? 1.177   -51.228 83.752  1.00 43.88  ? 250 ALA H CB  1 
ATOM   24098 N N   . ASP H 1 251 ? 3.751   -51.185 85.905  1.00 52.87  ? 251 ASP H N   1 
ATOM   24099 C CA  . ASP H 1 251 ? 4.950   -50.366 86.000  1.00 54.08  ? 251 ASP H CA  1 
ATOM   24100 C C   . ASP H 1 251 ? 5.211   -49.763 84.622  1.00 50.28  ? 251 ASP H C   1 
ATOM   24101 O O   . ASP H 1 251 ? 5.068   -48.553 84.427  1.00 47.21  ? 251 ASP H O   1 
ATOM   24102 C CB  . ASP H 1 251 ? 6.145   -51.193 86.483  1.00 56.83  ? 251 ASP H CB  1 
ATOM   24103 C CG  . ASP H 1 251 ? 7.406   -50.350 86.701  1.00 62.46  ? 251 ASP H CG  1 
ATOM   24104 O OD1 . ASP H 1 251 ? 7.801   -49.589 85.785  1.00 65.58  ? 251 ASP H OD1 1 
ATOM   24105 O OD2 . ASP H 1 251 ? 8.016   -50.467 87.791  1.00 61.34  ? 251 ASP H OD2 1 
ATOM   24106 N N   . GLN H 1 252 ? 5.556   -50.612 83.658  1.00 47.48  ? 252 GLN H N   1 
ATOM   24107 C CA  . GLN H 1 252 ? 5.912   -50.200 82.307  1.00 44.86  ? 252 GLN H CA  1 
ATOM   24108 C C   . GLN H 1 252 ? 4.755   -50.503 81.357  1.00 42.28  ? 252 GLN H C   1 
ATOM   24109 O O   . GLN H 1 252 ? 4.272   -51.638 81.318  1.00 40.38  ? 252 GLN H O   1 
ATOM   24110 C CB  . GLN H 1 252 ? 7.182   -50.936 81.866  1.00 43.93  ? 252 GLN H CB  1 
ATOM   24111 C CG  . GLN H 1 252 ? 7.967   -51.520 83.068  1.00 48.49  ? 252 GLN H CG  1 
ATOM   24112 C CD  . GLN H 1 252 ? 9.114   -52.473 82.699  1.00 47.46  ? 252 GLN H CD  1 
ATOM   24113 O OE1 . GLN H 1 252 ? 9.595   -52.490 81.566  1.00 49.79  ? 252 GLN H OE1 1 
ATOM   24114 N NE2 . GLN H 1 252 ? 9.568   -53.254 83.679  1.00 50.80  ? 252 GLN H NE2 1 
ATOM   24115 N N   . ARG H 1 253 ? 4.294   -49.483 80.616  1.00 38.07  ? 253 ARG H N   1 
ATOM   24116 C CA  . ARG H 1 253 ? 3.312   -49.634 79.539  1.00 36.02  ? 253 ARG H CA  1 
ATOM   24117 C C   . ARG H 1 253 ? 4.039   -49.390 78.224  1.00 39.37  ? 253 ARG H C   1 
ATOM   24118 O O   . ARG H 1 253 ? 4.355   -48.246 77.891  1.00 41.84  ? 253 ARG H O   1 
ATOM   24119 C CB  . ARG H 1 253 ? 2.140   -48.660 79.679  1.00 44.09  ? 253 ARG H CB  1 
ATOM   24120 C CG  . ARG H 1 253 ? 1.494   -48.603 81.053  1.00 52.05  ? 253 ARG H CG  1 
ATOM   24121 C CD  . ARG H 1 253 ? 0.159   -47.836 81.023  1.00 51.11  ? 253 ARG H CD  1 
ATOM   24122 N NE  . ARG H 1 253 ? -0.368  -47.511 82.350  1.00 52.49  ? 253 ARG H NE  1 
ATOM   24123 C CZ  . ARG H 1 253 ? 0.299   -46.882 83.318  1.00 58.99  ? 253 ARG H CZ  1 
ATOM   24124 N NH1 . ARG H 1 253 ? 1.544   -46.452 83.150  1.00 54.15  ? 253 ARG H NH1 1 
ATOM   24125 N NH2 . ARG H 1 253 ? -0.305  -46.663 84.485  1.00 58.36  ? 253 ARG H NH2 1 
ATOM   24126 N N   . PHE H 1 254 ? 4.275   -50.452 77.463  1.00 35.14  ? 254 PHE H N   1 
ATOM   24127 C CA  . PHE H 1 254 ? 5.074   -50.364 76.250  1.00 31.46  ? 254 PHE H CA  1 
ATOM   24128 C C   . PHE H 1 254 ? 4.253   -50.767 75.033  1.00 28.08  ? 254 PHE H C   1 
ATOM   24129 O O   . PHE H 1 254 ? 3.144   -51.292 75.146  1.00 28.35  ? 254 PHE H O   1 
ATOM   24130 C CB  . PHE H 1 254 ? 6.324   -51.252 76.362  1.00 27.37  ? 254 PHE H CB  1 
ATOM   24131 C CG  . PHE H 1 254 ? 6.023   -52.719 76.392  1.00 26.04  ? 254 PHE H CG  1 
ATOM   24132 C CD1 . PHE H 1 254 ? 5.894   -53.443 75.211  1.00 30.45  ? 254 PHE H CD1 1 
ATOM   24133 C CD2 . PHE H 1 254 ? 5.869   -53.383 77.596  1.00 31.90  ? 254 PHE H CD2 1 
ATOM   24134 C CE1 . PHE H 1 254 ? 5.617   -54.803 75.228  1.00 29.71  ? 254 PHE H CE1 1 
ATOM   24135 C CE2 . PHE H 1 254 ? 5.597   -54.747 77.626  1.00 30.80  ? 254 PHE H CE2 1 
ATOM   24136 C CZ  . PHE H 1 254 ? 5.466   -55.457 76.437  1.00 29.38  ? 254 PHE H CZ  1 
ATOM   24137 N N   . PHE H 1 255 ? 4.831   -50.539 73.854  1.00 27.32  ? 255 PHE H N   1 
ATOM   24138 C CA  . PHE H 1 255 ? 4.369   -51.197 72.642  1.00 25.98  ? 255 PHE H CA  1 
ATOM   24139 C C   . PHE H 1 255 ? 5.528   -51.339 71.665  1.00 22.85  ? 255 PHE H C   1 
ATOM   24140 O O   . PHE H 1 255 ? 6.444   -50.516 71.635  1.00 24.34  ? 255 PHE H O   1 
ATOM   24141 C CB  . PHE H 1 255 ? 3.161   -50.480 72.006  1.00 26.19  ? 255 PHE H CB  1 
ATOM   24142 C CG  . PHE H 1 255 ? 3.482   -49.208 71.216  1.00 30.17  ? 255 PHE H CG  1 
ATOM   24143 C CD1 . PHE H 1 255 ? 3.489   -47.964 71.834  1.00 26.70  ? 255 PHE H CD1 1 
ATOM   24144 C CD2 . PHE H 1 255 ? 3.682   -49.255 69.843  1.00 24.33  ? 255 PHE H CD2 1 
ATOM   24145 C CE1 . PHE H 1 255 ? 3.729   -46.796 71.102  1.00 27.54  ? 255 PHE H CE1 1 
ATOM   24146 C CE2 . PHE H 1 255 ? 3.945   -48.091 69.104  1.00 25.46  ? 255 PHE H CE2 1 
ATOM   24147 C CZ  . PHE H 1 255 ? 3.964   -46.859 69.730  1.00 27.42  ? 255 PHE H CZ  1 
ATOM   24148 N N   . PHE H 1 256 ? 5.501   -52.433 70.912  1.00 25.99  ? 256 PHE H N   1 
ATOM   24149 C CA  . PHE H 1 256 ? 6.487   -52.739 69.883  1.00 22.67  ? 256 PHE H CA  1 
ATOM   24150 C C   . PHE H 1 256 ? 5.853   -52.576 68.510  1.00 22.29  ? 256 PHE H C   1 
ATOM   24151 O O   . PHE H 1 256 ? 4.721   -53.006 68.294  1.00 24.36  ? 256 PHE H O   1 
ATOM   24152 C CB  . PHE H 1 256 ? 7.006   -54.164 70.013  1.00 21.83  ? 256 PHE H CB  1 
ATOM   24153 C CG  . PHE H 1 256 ? 7.707   -54.462 71.315  1.00 24.53  ? 256 PHE H CG  1 
ATOM   24154 C CD1 . PHE H 1 256 ? 8.349   -53.467 72.034  1.00 22.97  ? 256 PHE H CD1 1 
ATOM   24155 C CD2 . PHE H 1 256 ? 7.742   -55.767 71.805  1.00 19.54  ? 256 PHE H CD2 1 
ATOM   24156 C CE1 . PHE H 1 256 ? 8.994   -53.765 73.228  1.00 25.14  ? 256 PHE H CE1 1 
ATOM   24157 C CE2 . PHE H 1 256 ? 8.390   -56.073 72.999  1.00 19.52  ? 256 PHE H CE2 1 
ATOM   24158 C CZ  . PHE H 1 256 ? 9.012   -55.080 73.710  1.00 22.63  ? 256 PHE H CZ  1 
ATOM   24159 N N   . GLU H 1 257 ? 6.586   -51.975 67.573  1.00 24.63  ? 257 GLU H N   1 
ATOM   24160 C CA  . GLU H 1 257 ? 6.091   -51.759 66.215  1.00 23.23  ? 257 GLU H CA  1 
ATOM   24161 C C   . GLU H 1 257 ? 6.989   -52.463 65.199  1.00 20.14  ? 257 GLU H C   1 
ATOM   24162 O O   . GLU H 1 257 ? 8.217   -52.447 65.327  1.00 22.67  ? 257 GLU H O   1 
ATOM   24163 C CB  . GLU H 1 257 ? 6.010   -50.259 65.890  1.00 20.24  ? 257 GLU H CB  1 
ATOM   24164 C CG  . GLU H 1 257 ? 5.460   -49.972 64.493  1.00 19.80  ? 257 GLU H CG  1 
ATOM   24165 C CD  . GLU H 1 257 ? 4.868   -48.586 64.390  1.00 22.07  ? 257 GLU H CD  1 
ATOM   24166 O OE1 . GLU H 1 257 ? 5.326   -47.677 65.116  1.00 25.24  ? 257 GLU H OE1 1 
ATOM   24167 O OE2 . GLU H 1 257 ? 3.906   -48.412 63.626  1.00 24.45  ? 257 GLU H OE2 1 
ATOM   24168 N N   . TYR H 1 258 ? 6.366   -53.059 64.180  1.00 15.50  ? 258 TYR H N   1 
ATOM   24169 C CA  . TYR H 1 258 ? 7.036   -53.908 63.205  1.00 18.51  ? 258 TYR H CA  1 
ATOM   24170 C C   . TYR H 1 258 ? 6.571   -53.563 61.798  1.00 18.80  ? 258 TYR H C   1 
ATOM   24171 O O   . TYR H 1 258 ? 5.441   -53.112 61.593  1.00 17.75  ? 258 TYR H O   1 
ATOM   24172 C CB  . TYR H 1 258 ? 6.760   -55.426 63.408  1.00 18.17  ? 258 TYR H CB  1 
ATOM   24173 C CG  . TYR H 1 258 ? 7.022   -55.961 64.800  1.00 20.52  ? 258 TYR H CG  1 
ATOM   24174 C CD1 . TYR H 1 258 ? 6.206   -55.602 65.870  1.00 17.88  ? 258 TYR H CD1 1 
ATOM   24175 C CD2 . TYR H 1 258 ? 8.065   -56.842 65.037  1.00 20.54  ? 258 TYR H CD2 1 
ATOM   24176 C CE1 . TYR H 1 258 ? 6.454   -56.060 67.136  1.00 20.16  ? 258 TYR H CE1 1 
ATOM   24177 C CE2 . TYR H 1 258 ? 8.318   -57.313 66.300  1.00 20.77  ? 258 TYR H CE2 1 
ATOM   24178 C CZ  . TYR H 1 258 ? 7.506   -56.920 67.347  1.00 24.37  ? 258 TYR H CZ  1 
ATOM   24179 O OH  . TYR H 1 258 ? 7.740   -57.393 68.617  1.00 23.97  ? 258 TYR H OH  1 
ATOM   24180 N N   . HIS H 1 259 ? 7.447   -53.820 60.833  1.00 15.95  ? 259 HIS H N   1 
ATOM   24181 C CA  . HIS H 1 259 ? 7.115   -53.853 59.418  1.00 17.64  ? 259 HIS H CA  1 
ATOM   24182 C C   . HIS H 1 259 ? 7.183   -55.299 58.942  1.00 19.80  ? 259 HIS H C   1 
ATOM   24183 O O   . HIS H 1 259 ? 8.168   -55.996 59.200  1.00 21.64  ? 259 HIS H O   1 
ATOM   24184 C CB  . HIS H 1 259 ? 8.087   -52.988 58.612  1.00 21.53  ? 259 HIS H CB  1 
ATOM   24185 C CG  . HIS H 1 259 ? 7.885   -53.066 57.134  1.00 20.81  ? 259 HIS H CG  1 
ATOM   24186 N ND1 . HIS H 1 259 ? 8.646   -53.880 56.323  1.00 23.37  ? 259 HIS H ND1 1 
ATOM   24187 C CD2 . HIS H 1 259 ? 7.010   -52.428 56.316  1.00 20.51  ? 259 HIS H CD2 1 
ATOM   24188 C CE1 . HIS H 1 259 ? 8.244   -53.744 55.067  1.00 26.18  ? 259 HIS H CE1 1 
ATOM   24189 N NE2 . HIS H 1 259 ? 7.252   -52.871 55.034  1.00 23.17  ? 259 HIS H NE2 1 
ATOM   24190 N N   . LEU H 1 260 ? 6.149   -55.742 58.242  1.00 21.03  ? 260 LEU H N   1 
ATOM   24191 C CA  . LEU H 1 260 ? 6.041   -57.119 57.785  1.00 21.25  ? 260 LEU H CA  1 
ATOM   24192 C C   . LEU H 1 260 ? 5.992   -57.129 56.264  1.00 21.89  ? 260 LEU H C   1 
ATOM   24193 O O   . LEU H 1 260 ? 5.183   -56.419 55.663  1.00 18.96  ? 260 LEU H O   1 
ATOM   24194 C CB  . LEU H 1 260 ? 4.780   -57.800 58.354  1.00 19.25  ? 260 LEU H CB  1 
ATOM   24195 C CG  . LEU H 1 260 ? 4.841   -58.413 59.752  1.00 22.02  ? 260 LEU H CG  1 
ATOM   24196 C CD1 . LEU H 1 260 ? 5.250   -57.400 60.821  1.00 18.31  ? 260 LEU H CD1 1 
ATOM   24197 C CD2 . LEU H 1 260 ? 3.496   -59.034 60.106  1.00 22.53  ? 260 LEU H CD2 1 
ATOM   24198 N N   . ASP H 1 261 ? 6.858   -57.932 55.650  1.00 21.74  ? 261 ASP H N   1 
ATOM   24199 C CA  . ASP H 1 261 ? 6.784   -58.169 54.215  1.00 22.67  ? 261 ASP H CA  1 
ATOM   24200 C C   . ASP H 1 261 ? 6.913   -59.660 53.986  1.00 21.65  ? 261 ASP H C   1 
ATOM   24201 O O   . ASP H 1 261 ? 6.839   -60.440 54.942  1.00 22.73  ? 261 ASP H O   1 
ATOM   24202 C CB  . ASP H 1 261 ? 7.849   -57.384 53.431  1.00 25.91  ? 261 ASP H CB  1 
ATOM   24203 C CG  . ASP H 1 261 ? 9.301   -57.694 53.872  1.00 25.73  ? 261 ASP H CG  1 
ATOM   24204 O OD1 . ASP H 1 261 ? 9.610   -58.801 54.372  1.00 25.01  ? 261 ASP H OD1 1 
ATOM   24205 O OD2 . ASP H 1 261 ? 10.151  -56.799 53.692  1.00 24.42  ? 261 ASP H OD2 1 
ATOM   24206 N N   . GLY H 1 262 ? 7.088   -60.070 52.734  1.00 24.79  ? 262 GLY H N   1 
ATOM   24207 C CA  . GLY H 1 262 ? 7.220   -61.492 52.464  1.00 26.36  ? 262 GLY H CA  1 
ATOM   24208 C C   . GLY H 1 262 ? 8.534   -62.097 52.908  1.00 20.94  ? 262 GLY H C   1 
ATOM   24209 O O   . GLY H 1 262 ? 8.663   -63.322 52.880  1.00 29.02  ? 262 GLY H O   1 
ATOM   24210 N N   . ASP H 1 263 ? 9.503   -61.288 53.326  1.00 22.37  ? 263 ASP H N   1 
ATOM   24211 C CA  . ASP H 1 263 ? 10.782  -61.815 53.812  1.00 29.27  ? 263 ASP H CA  1 
ATOM   24212 C C   . ASP H 1 263 ? 10.862  -61.916 55.326  1.00 29.22  ? 263 ASP H C   1 
ATOM   24213 O O   . ASP H 1 263 ? 11.524  -62.833 55.828  1.00 29.84  ? 263 ASP H O   1 
ATOM   24214 C CB  . ASP H 1 263 ? 11.963  -60.941 53.358  1.00 26.47  ? 263 ASP H CB  1 
ATOM   24215 C CG  . ASP H 1 263 ? 12.180  -60.961 51.860  1.00 32.33  ? 263 ASP H CG  1 
ATOM   24216 O OD1 . ASP H 1 263 ? 12.192  -62.058 51.258  1.00 30.53  ? 263 ASP H OD1 1 
ATOM   24217 O OD2 . ASP H 1 263 ? 12.325  -59.857 51.278  1.00 35.93  ? 263 ASP H OD2 1 
ATOM   24218 N N   . ARG H 1 264 ? 10.225  -61.003 56.068  1.00 25.01  ? 264 ARG H N   1 
ATOM   24219 C CA  . ARG H 1 264 ? 10.505  -60.903 57.503  1.00 30.07  ? 264 ARG H CA  1 
ATOM   24220 C C   . ARG H 1 264 ? 9.498   -59.983 58.174  1.00 28.64  ? 264 ARG H C   1 
ATOM   24221 O O   . ARG H 1 264 ? 8.886   -59.121 57.531  1.00 23.15  ? 264 ARG H O   1 
ATOM   24222 C CB  . ARG H 1 264 ? 11.905  -60.334 57.763  1.00 25.96  ? 264 ARG H CB  1 
ATOM   24223 C CG  . ARG H 1 264 ? 12.113  -59.108 56.907  1.00 28.33  ? 264 ARG H CG  1 
ATOM   24224 C CD  . ARG H 1 264 ? 12.340  -57.912 57.731  1.00 31.53  ? 264 ARG H CD  1 
ATOM   24225 N NE  . ARG H 1 264 ? 12.415  -56.670 56.960  1.00 31.55  ? 264 ARG H NE  1 
ATOM   24226 C CZ  . ARG H 1 264 ? 11.386  -55.967 56.503  1.00 27.00  ? 264 ARG H CZ  1 
ATOM   24227 N NH1 . ARG H 1 264 ? 10.136  -56.395 56.625  1.00 23.55  ? 264 ARG H NH1 1 
ATOM   24228 N NH2 . ARG H 1 264 ? 11.614  -54.788 55.932  1.00 26.30  ? 264 ARG H NH2 1 
ATOM   24229 N N   . ALA H 1 265 ? 9.387   -60.139 59.490  1.00 22.80  ? 265 ALA H N   1 
ATOM   24230 C CA  . ALA H 1 265 ? 8.803   -59.117 60.352  1.00 26.25  ? 265 ALA H CA  1 
ATOM   24231 C C   . ALA H 1 265 ? 9.952   -58.310 60.952  1.00 27.64  ? 265 ALA H C   1 
ATOM   24232 O O   . ALA H 1 265 ? 10.743  -58.834 61.745  1.00 24.31  ? 265 ALA H O   1 
ATOM   24233 C CB  . ALA H 1 265 ? 7.941   -59.742 61.448  1.00 24.48  ? 265 ALA H CB  1 
ATOM   24234 N N   . ARG H 1 266 ? 10.045  -57.043 60.573  1.00 27.55  ? 266 ARG H N   1 
ATOM   24235 C CA  . ARG H 1 266 ? 11.138  -56.168 60.994  1.00 26.54  ? 266 ARG H CA  1 
ATOM   24236 C C   . ARG H 1 266 ? 10.745  -55.458 62.278  1.00 23.13  ? 266 ARG H C   1 
ATOM   24237 O O   . ARG H 1 266 ? 9.794   -54.680 62.279  1.00 19.63  ? 266 ARG H O   1 
ATOM   24238 C CB  . ARG H 1 266 ? 11.444  -55.130 59.916  1.00 25.02  ? 266 ARG H CB  1 
ATOM   24239 C CG  . ARG H 1 266 ? 12.770  -54.452 60.073  1.00 29.73  ? 266 ARG H CG  1 
ATOM   24240 C CD  . ARG H 1 266 ? 13.846  -55.408 59.644  1.00 36.54  ? 266 ARG H CD  1 
ATOM   24241 N NE  . ARG H 1 266 ? 14.567  -55.979 60.762  1.00 38.82  ? 266 ARG H NE  1 
ATOM   24242 C CZ  . ARG H 1 266 ? 15.320  -57.062 60.652  1.00 41.01  ? 266 ARG H CZ  1 
ATOM   24243 N NH1 . ARG H 1 266 ? 15.525  -57.636 59.477  1.00 39.49  ? 266 ARG H NH1 1 
ATOM   24244 N NH2 . ARG H 1 266 ? 15.860  -57.591 61.745  1.00 40.76  ? 266 ARG H NH2 1 
ATOM   24245 N N   . PHE H 1 267 ? 11.482  -55.702 63.362  1.00 25.59  ? 267 PHE H N   1 
ATOM   24246 C CA  . PHE H 1 267 ? 11.315  -54.894 64.567  1.00 23.17  ? 267 PHE H CA  1 
ATOM   24247 C C   . PHE H 1 267 ? 11.837  -53.476 64.322  1.00 22.47  ? 267 PHE H C   1 
ATOM   24248 O O   . PHE H 1 267 ? 13.018  -53.286 64.025  1.00 28.68  ? 267 PHE H O   1 
ATOM   24249 C CB  . PHE H 1 267 ? 12.043  -55.547 65.743  1.00 24.79  ? 267 PHE H CB  1 
ATOM   24250 C CG  . PHE H 1 267 ? 11.890  -54.803 67.048  1.00 26.00  ? 267 PHE H CG  1 
ATOM   24251 C CD1 . PHE H 1 267 ? 12.723  -53.750 67.373  1.00 26.93  ? 267 PHE H CD1 1 
ATOM   24252 C CD2 . PHE H 1 267 ? 10.904  -55.165 67.961  1.00 30.56  ? 267 PHE H CD2 1 
ATOM   24253 C CE1 . PHE H 1 267 ? 12.574  -53.055 68.582  1.00 26.38  ? 267 PHE H CE1 1 
ATOM   24254 C CE2 . PHE H 1 267 ? 10.756  -54.477 69.167  1.00 27.31  ? 267 PHE H CE2 1 
ATOM   24255 C CZ  . PHE H 1 267 ? 11.597  -53.426 69.480  1.00 21.54  ? 267 PHE H CZ  1 
ATOM   24256 N N   . LEU H 1 268 ? 10.964  -52.477 64.462  1.00 23.44  ? 268 LEU H N   1 
ATOM   24257 C CA  . LEU H 1 268 ? 11.307  -51.072 64.254  1.00 19.64  ? 268 LEU H CA  1 
ATOM   24258 C C   . LEU H 1 268 ? 11.699  -50.340 65.536  1.00 23.55  ? 268 LEU H C   1 
ATOM   24259 O O   . LEU H 1 268 ? 12.751  -49.696 65.583  1.00 21.74  ? 268 LEU H O   1 
ATOM   24260 C CB  . LEU H 1 268 ? 10.129  -50.359 63.599  1.00 23.72  ? 268 LEU H CB  1 
ATOM   24261 C CG  . LEU H 1 268 ? 9.609   -51.079 62.352  1.00 22.77  ? 268 LEU H CG  1 
ATOM   24262 C CD1 . LEU H 1 268 ? 8.405   -50.349 61.767  1.00 20.57  ? 268 LEU H CD1 1 
ATOM   24263 C CD2 . LEU H 1 268 ? 10.742  -51.207 61.311  1.00 24.12  ? 268 LEU H CD2 1 
ATOM   24264 N N   . HIS H 1 269 ? 10.875  -50.418 66.583  1.00 21.57  ? 269 HIS H N   1 
ATOM   24265 C CA  . HIS H 1 269 ? 11.165  -49.684 67.801  1.00 23.11  ? 269 HIS H CA  1 
ATOM   24266 C C   . HIS H 1 269 ? 10.212  -50.129 68.909  1.00 22.54  ? 269 HIS H C   1 
ATOM   24267 O O   . HIS H 1 269 ? 9.162   -50.724 68.652  1.00 24.65  ? 269 HIS H O   1 
ATOM   24268 C CB  . HIS H 1 269 ? 11.044  -48.173 67.573  1.00 20.08  ? 269 HIS H CB  1 
ATOM   24269 C CG  . HIS H 1 269 ? 9.652   -47.732 67.279  1.00 20.03  ? 269 HIS H CG  1 
ATOM   24270 N ND1 . HIS H 1 269 ? 8.800   -47.278 68.261  1.00 23.31  ? 269 HIS H ND1 1 
ATOM   24271 C CD2 . HIS H 1 269 ? 8.950   -47.695 66.123  1.00 20.63  ? 269 HIS H CD2 1 
ATOM   24272 C CE1 . HIS H 1 269 ? 7.634   -46.970 67.721  1.00 21.20  ? 269 HIS H CE1 1 
ATOM   24273 N NE2 . HIS H 1 269 ? 7.697   -47.220 66.425  1.00 22.74  ? 269 HIS H NE2 1 
ATOM   24274 N N   . SER H 1 270 ? 10.601  -49.831 70.143  1.00 20.56  ? 270 SER H N   1 
ATOM   24275 C CA  . SER H 1 270 ? 9.714   -49.826 71.300  1.00 25.69  ? 270 SER H CA  1 
ATOM   24276 C C   . SER H 1 270 ? 9.460   -48.381 71.715  1.00 25.63  ? 270 SER H C   1 
ATOM   24277 O O   . SER H 1 270 ? 10.342  -47.532 71.578  1.00 29.46  ? 270 SER H O   1 
ATOM   24278 C CB  . SER H 1 270 ? 10.341  -50.573 72.466  1.00 24.26  ? 270 SER H CB  1 
ATOM   24279 O OG  . SER H 1 270 ? 11.538  -49.906 72.815  1.00 26.44  ? 270 SER H OG  1 
ATOM   24280 N N   . SER H 1 271 ? 8.255   -48.098 72.216  1.00 24.38  ? 271 SER H N   1 
ATOM   24281 C CA  . SER H 1 271 ? 7.918   -46.761 72.705  1.00 26.02  ? 271 SER H CA  1 
ATOM   24282 C C   . SER H 1 271 ? 6.971   -46.874 73.900  1.00 25.95  ? 271 SER H C   1 
ATOM   24283 O O   . SER H 1 271 ? 6.338   -47.910 74.113  1.00 28.95  ? 271 SER H O   1 
ATOM   24284 C CB  . SER H 1 271 ? 7.306   -45.913 71.585  1.00 25.58  ? 271 SER H CB  1 
ATOM   24285 O OG  . SER H 1 271 ? 8.227   -45.761 70.505  1.00 28.68  ? 271 SER H OG  1 
ATOM   24286 N N   . ILE H 1 272 ? 6.883   -45.807 74.694  1.00 26.33  ? 272 ILE H N   1 
ATOM   24287 C CA  . ILE H 1 272 ? 6.096   -45.806 75.934  1.00 27.92  ? 272 ILE H CA  1 
ATOM   24288 C C   . ILE H 1 272 ? 4.946   -44.817 75.791  1.00 31.72  ? 272 ILE H C   1 
ATOM   24289 O O   . ILE H 1 272 ? 5.175   -43.612 75.630  1.00 28.48  ? 272 ILE H O   1 
ATOM   24290 C CB  . ILE H 1 272 ? 6.944   -45.435 77.160  1.00 33.98  ? 272 ILE H CB  1 
ATOM   24291 C CG1 . ILE H 1 272 ? 8.064   -46.434 77.425  1.00 30.06  ? 272 ILE H CG1 1 
ATOM   24292 C CG2 . ILE H 1 272 ? 6.067   -45.298 78.402  1.00 32.17  ? 272 ILE H CG2 1 
ATOM   24293 C CD1 . ILE H 1 272 ? 8.977   -45.986 78.583  1.00 29.64  ? 272 ILE H CD1 1 
ATOM   24294 N N   . LEU H 1 273 ? 3.714   -45.329 75.877  1.00 33.67  ? 273 LEU H N   1 
ATOM   24295 C CA  . LEU H 1 273 ? 2.487   -44.539 75.988  1.00 36.04  ? 273 LEU H CA  1 
ATOM   24296 C C   . LEU H 1 273 ? 2.489   -43.693 77.255  1.00 36.75  ? 273 LEU H C   1 
ATOM   24297 O O   . LEU H 1 273 ? 2.449   -44.232 78.369  1.00 38.49  ? 273 LEU H O   1 
ATOM   24298 C CB  . LEU H 1 273 ? 1.249   -45.448 76.028  1.00 35.57  ? 273 LEU H CB  1 
ATOM   24299 C CG  . LEU H 1 273 ? 0.792   -46.304 74.852  1.00 43.24  ? 273 LEU H CG  1 
ATOM   24300 C CD1 . LEU H 1 273 ? 0.786   -47.795 75.266  1.00 37.10  ? 273 LEU H CD1 1 
ATOM   24301 C CD2 . LEU H 1 273 ? -0.598  -45.846 74.413  1.00 39.34  ? 273 LEU H CD2 1 
ATOM   24302 N N   . LYS H 1 274 ? 2.512   -42.378 77.115  1.00 37.30  ? 274 LYS H N   1 
ATOM   24303 C CA  . LYS H 1 274 ? 2.596   -41.498 78.269  1.00 40.81  ? 274 LYS H CA  1 
ATOM   24304 C C   . LYS H 1 274 ? 1.221   -40.896 78.499  1.00 48.15  ? 274 LYS H C   1 
ATOM   24305 O O   . LYS H 1 274 ? 0.606   -40.371 77.561  1.00 48.77  ? 274 LYS H O   1 
ATOM   24306 C CB  . LYS H 1 274 ? 3.663   -40.420 78.059  1.00 38.50  ? 274 LYS H CB  1 
ATOM   24307 C CG  . LYS H 1 274 ? 3.617   -39.255 79.049  1.00 49.97  ? 274 LYS H CG  1 
ATOM   24308 C CD  . LYS H 1 274 ? 4.998   -38.908 79.637  1.00 50.98  ? 274 LYS H CD  1 
ATOM   24309 C CE  . LYS H 1 274 ? 5.851   -38.002 78.718  1.00 48.00  ? 274 LYS H CE  1 
ATOM   24310 N NZ  . LYS H 1 274 ? 5.151   -36.826 78.108  1.00 44.48  ? 274 LYS H NZ  1 
ATOM   24311 N N   . TYR H 1 275 ? 0.720   -41.018 79.729  1.00 45.69  ? 275 TYR H N   1 
ATOM   24312 C CA  . TYR H 1 275 ? -0.595  -40.510 80.098  1.00 51.50  ? 275 TYR H CA  1 
ATOM   24313 C C   . TYR H 1 275 ? -0.444  -39.411 81.145  1.00 51.85  ? 275 TYR H C   1 
ATOM   24314 O O   . TYR H 1 275 ? 0.587   -39.312 81.817  1.00 53.55  ? 275 TYR H O   1 
ATOM   24315 C CB  . TYR H 1 275 ? -1.491  -41.631 80.630  1.00 45.96  ? 275 TYR H CB  1 
ATOM   24316 C CG  . TYR H 1 275 ? -1.825  -42.708 79.614  1.00 44.98  ? 275 TYR H CG  1 
ATOM   24317 C CD1 . TYR H 1 275 ? -0.965  -43.780 79.393  1.00 44.86  ? 275 TYR H CD1 1 
ATOM   24318 C CD2 . TYR H 1 275 ? -3.009  -42.664 78.894  1.00 44.02  ? 275 TYR H CD2 1 
ATOM   24319 C CE1 . TYR H 1 275 ? -1.270  -44.771 78.469  1.00 40.05  ? 275 TYR H CE1 1 
ATOM   24320 C CE2 . TYR H 1 275 ? -3.323  -43.650 77.979  1.00 46.36  ? 275 TYR H CE2 1 
ATOM   24321 C CZ  . TYR H 1 275 ? -2.449  -44.702 77.771  1.00 42.60  ? 275 TYR H CZ  1 
ATOM   24322 O OH  . TYR H 1 275 ? -2.767  -45.679 76.856  1.00 47.58  ? 275 TYR H OH  1 
ATOM   24323 N N   . GLU H 1 276 ? -1.473  -38.574 81.279  1.00 51.82  ? 276 GLU H N   1 
ATOM   24324 C CA  . GLU H 1 276 ? -1.405  -37.426 82.180  1.00 63.51  ? 276 GLU H CA  1 
ATOM   24325 C C   . GLU H 1 276 ? -1.824  -37.797 83.598  1.00 62.35  ? 276 GLU H C   1 
ATOM   24326 O O   . GLU H 1 276 ? -2.817  -38.498 83.798  1.00 60.22  ? 276 GLU H O   1 
ATOM   24327 C CB  . GLU H 1 276 ? -2.275  -36.271 81.677  1.00 66.40  ? 276 GLU H CB  1 
ATOM   24328 C CG  . GLU H 1 276 ? -1.792  -34.896 82.165  1.00 67.82  ? 276 GLU H CG  1 
ATOM   24329 C CD  . GLU H 1 276 ? -2.085  -33.767 81.181  1.00 74.65  ? 276 GLU H CD  1 
ATOM   24330 O OE1 . GLU H 1 276 ? -2.918  -33.955 80.265  1.00 71.08  ? 276 GLU H OE1 1 
ATOM   24331 O OE2 . GLU H 1 276 ? -1.465  -32.688 81.321  1.00 78.09  ? 276 GLU H OE2 1 
ATOM   24332 N N   . GLN H 1 277 ? -1.053  -37.316 84.577  1.00 62.47  ? 277 GLN H N   1 
ATOM   24333 C CA  . GLN H 1 277 ? -1.397  -37.461 85.993  1.00 67.59  ? 277 GLN H CA  1 
ATOM   24334 C C   . GLN H 1 277 ? -2.257  -36.293 86.444  1.00 64.53  ? 277 GLN H C   1 
ATOM   24335 O O   . GLN H 1 277 ? -1.818  -35.144 86.383  1.00 65.84  ? 277 GLN H O   1 
ATOM   24336 C CB  . GLN H 1 277 ? -0.142  -37.532 86.866  1.00 68.77  ? 277 GLN H CB  1 
ATOM   24337 C CG  . GLN H 1 277 ? 1.085   -38.161 86.209  1.00 68.54  ? 277 GLN H CG  1 
ATOM   24338 C CD  . GLN H 1 277 ? 1.063   -39.687 86.245  1.00 70.56  ? 277 GLN H CD  1 
ATOM   24339 O OE1 . GLN H 1 277 ? 0.860   -40.343 85.221  1.00 62.96  ? 277 GLN H OE1 1 
ATOM   24340 N NE2 . GLN H 1 277 ? 1.273   -40.257 87.431  1.00 66.33  ? 277 GLN H NE2 1 
ATOM   24341 N N   . SER H 1 285 ? -10.586 -39.595 82.565  1.00 57.83  ? 285 SER H N   1 
ATOM   24342 C CA  . SER H 1 285 ? -9.954  -40.723 83.244  1.00 56.25  ? 285 SER H CA  1 
ATOM   24343 C C   . SER H 1 285 ? -8.464  -40.473 83.385  1.00 52.52  ? 285 SER H C   1 
ATOM   24344 O O   . SER H 1 285 ? -8.009  -39.873 84.356  1.00 55.37  ? 285 SER H O   1 
ATOM   24345 C CB  . SER H 1 285 ? -10.198 -42.023 82.481  1.00 42.43  ? 285 SER H CB  1 
ATOM   24346 O OG  . SER H 1 285 ? -11.579 -42.240 82.260  1.00 46.12  ? 285 SER H OG  1 
ATOM   24347 N N   . ALA H 1 286 ? -7.703  -40.950 82.405  1.00 50.58  ? 286 ALA H N   1 
ATOM   24348 C CA  . ALA H 1 286 ? -6.294  -40.583 82.281  1.00 51.01  ? 286 ALA H CA  1 
ATOM   24349 C C   . ALA H 1 286 ? -5.975  -40.611 80.789  1.00 50.78  ? 286 ALA H C   1 
ATOM   24350 O O   . ALA H 1 286 ? -5.749  -41.682 80.221  1.00 50.06  ? 286 ALA H O   1 
ATOM   24351 C CB  . ALA H 1 286 ? -5.402  -41.523 83.075  1.00 51.19  ? 286 ALA H CB  1 
ATOM   24352 N N   . LYS H 1 287 ? -5.976  -39.439 80.161  1.00 54.08  ? 287 LYS H N   1 
ATOM   24353 C CA  . LYS H 1 287 ? -5.902  -39.380 78.712  1.00 59.40  ? 287 LYS H CA  1 
ATOM   24354 C C   . LYS H 1 287 ? -4.443  -39.410 78.235  1.00 56.81  ? 287 LYS H C   1 
ATOM   24355 O O   . LYS H 1 287 ? -3.487  -39.466 79.020  1.00 51.12  ? 287 LYS H O   1 
ATOM   24356 C CB  . LYS H 1 287 ? -6.671  -38.157 78.195  1.00 58.42  ? 287 LYS H CB  1 
ATOM   24357 C CG  . LYS H 1 287 ? -5.938  -36.818 78.291  1.00 60.95  ? 287 LYS H CG  1 
ATOM   24358 C CD  . LYS H 1 287 ? -6.437  -35.812 77.249  1.00 56.48  ? 287 LYS H CD  1 
ATOM   24359 C CE  . LYS H 1 287 ? -7.858  -35.313 77.560  1.00 57.68  ? 287 LYS H CE  1 
ATOM   24360 N NZ  . LYS H 1 287 ? -8.073  -35.033 79.011  1.00 51.83  ? 287 LYS H NZ  1 
ATOM   24361 N N   . TRP H 1 288 ? -4.285  -39.385 76.915  1.00 55.92  ? 288 TRP H N   1 
ATOM   24362 C CA  . TRP H 1 288 ? -3.012  -39.624 76.251  1.00 49.78  ? 288 TRP H CA  1 
ATOM   24363 C C   . TRP H 1 288 ? -2.329  -38.297 75.933  1.00 46.40  ? 288 TRP H C   1 
ATOM   24364 O O   . TRP H 1 288 ? -2.953  -37.391 75.370  1.00 50.51  ? 288 TRP H O   1 
ATOM   24365 C CB  . TRP H 1 288 ? -3.270  -40.441 74.984  1.00 44.20  ? 288 TRP H CB  1 
ATOM   24366 C CG  . TRP H 1 288 ? -2.087  -40.710 74.120  1.00 48.16  ? 288 TRP H CG  1 
ATOM   24367 C CD1 . TRP H 1 288 ? -0.876  -41.224 74.503  1.00 44.02  ? 288 TRP H CD1 1 
ATOM   24368 C CD2 . TRP H 1 288 ? -2.008  -40.500 72.709  1.00 47.78  ? 288 TRP H CD2 1 
ATOM   24369 N NE1 . TRP H 1 288 ? -0.050  -41.338 73.414  1.00 41.90  ? 288 TRP H NE1 1 
ATOM   24370 C CE2 . TRP H 1 288 ? -0.718  -40.894 72.301  1.00 45.17  ? 288 TRP H CE2 1 
ATOM   24371 C CE3 . TRP H 1 288 ? -2.904  -40.017 71.751  1.00 45.23  ? 288 TRP H CE3 1 
ATOM   24372 C CZ2 . TRP H 1 288 ? -0.301  -40.813 70.981  1.00 44.69  ? 288 TRP H CZ2 1 
ATOM   24373 C CZ3 . TRP H 1 288 ? -2.488  -39.938 70.442  1.00 45.64  ? 288 TRP H CZ3 1 
ATOM   24374 C CH2 . TRP H 1 288 ? -1.199  -40.339 70.066  1.00 45.71  ? 288 TRP H CH2 1 
ATOM   24375 N N   . ILE H 1 289 ? -1.053  -38.180 76.304  1.00 41.57  ? 289 ILE H N   1 
ATOM   24376 C CA  . ILE H 1 289 ? -0.306  -36.943 76.104  1.00 44.47  ? 289 ILE H CA  1 
ATOM   24377 C C   . ILE H 1 289 ? 0.922   -37.105 75.215  1.00 44.36  ? 289 ILE H C   1 
ATOM   24378 O O   . ILE H 1 289 ? 1.460   -36.086 74.759  1.00 43.28  ? 289 ILE H O   1 
ATOM   24379 C CB  . ILE H 1 289 ? 0.097   -36.293 77.449  1.00 48.28  ? 289 ILE H CB  1 
ATOM   24380 C CG1 . ILE H 1 289 ? 0.551   -37.341 78.469  1.00 50.92  ? 289 ILE H CG1 1 
ATOM   24381 C CG2 . ILE H 1 289 ? -1.060  -35.502 78.022  1.00 49.01  ? 289 ILE H CG2 1 
ATOM   24382 C CD1 . ILE H 1 289 ? 1.077   -36.740 79.767  1.00 46.23  ? 289 ILE H CD1 1 
ATOM   24383 N N   . GLY H 1 290 ? 1.383   -38.319 74.935  1.00 44.08  ? 290 GLY H N   1 
ATOM   24384 C CA  . GLY H 1 290 ? 2.491   -38.497 74.016  1.00 37.25  ? 290 GLY H CA  1 
ATOM   24385 C C   . GLY H 1 290 ? 3.203   -39.825 74.193  1.00 35.69  ? 290 GLY H C   1 
ATOM   24386 O O   . GLY H 1 290 ? 2.814   -40.670 74.994  1.00 35.72  ? 290 GLY H O   1 
ATOM   24387 N N   . LEU H 1 291 ? 4.269   -39.994 73.406  1.00 34.96  ? 291 LEU H N   1 
ATOM   24388 C CA  . LEU H 1 291 ? 5.121   -41.172 73.497  1.00 32.35  ? 291 LEU H CA  1 
ATOM   24389 C C   . LEU H 1 291 ? 6.538   -40.768 73.862  1.00 31.91  ? 291 LEU H C   1 
ATOM   24390 O O   . LEU H 1 291 ? 7.033   -39.734 73.399  1.00 31.65  ? 291 LEU H O   1 
ATOM   24391 C CB  . LEU H 1 291 ? 5.154   -41.959 72.186  1.00 27.10  ? 291 LEU H CB  1 
ATOM   24392 C CG  . LEU H 1 291 ? 3.815   -42.321 71.552  1.00 31.91  ? 291 LEU H CG  1 
ATOM   24393 C CD1 . LEU H 1 291 ? 4.060   -43.233 70.387  1.00 31.58  ? 291 LEU H CD1 1 
ATOM   24394 C CD2 . LEU H 1 291 ? 2.886   -42.993 72.538  1.00 35.12  ? 291 LEU H CD2 1 
ATOM   24395 N N   . ASP H 1 292 ? 7.180   -41.590 74.700  1.00 28.51  ? 292 ASP H N   1 
ATOM   24396 C CA  . ASP H 1 292 ? 8.621   -41.574 74.904  1.00 27.37  ? 292 ASP H CA  1 
ATOM   24397 C C   . ASP H 1 292 ? 9.217   -42.798 74.220  1.00 32.70  ? 292 ASP H C   1 
ATOM   24398 O O   . ASP H 1 292 ? 8.619   -43.883 74.237  1.00 29.51  ? 292 ASP H O   1 
ATOM   24399 C CB  . ASP H 1 292 ? 9.002   -41.597 76.394  1.00 31.07  ? 292 ASP H CB  1 
ATOM   24400 C CG  . ASP H 1 292 ? 8.480   -40.391 77.168  1.00 35.27  ? 292 ASP H CG  1 
ATOM   24401 O OD1 . ASP H 1 292 ? 7.993   -39.424 76.539  1.00 32.13  ? 292 ASP H OD1 1 
ATOM   24402 O OD2 . ASP H 1 292 ? 8.567   -40.414 78.414  1.00 30.34  ? 292 ASP H OD2 1 
ATOM   24403 N N   . SER H 1 293 ? 10.396  -42.635 73.620  1.00 28.10  ? 293 SER H N   1 
ATOM   24404 C CA  . SER H 1 293 ? 10.977  -43.808 72.995  1.00 32.50  ? 293 SER H CA  1 
ATOM   24405 C C   . SER H 1 293 ? 12.431  -43.971 73.383  1.00 32.98  ? 293 SER H C   1 
ATOM   24406 O O   . SER H 1 293 ? 13.003  -43.087 74.023  1.00 30.66  ? 293 SER H O   1 
ATOM   24407 C CB  . SER H 1 293 ? 10.839  -43.803 71.480  1.00 31.94  ? 293 SER H CB  1 
ATOM   24408 O OG  . SER H 1 293 ? 11.125  -45.103 70.968  1.00 28.26  ? 293 SER H OG  1 
ATOM   24409 N N   . PRO H 1 294 ? 13.096  -44.949 72.825  1.00 36.69  ? 294 PRO H N   1 
ATOM   24410 C CA  . PRO H 1 294 ? 13.374  -46.164 73.593  1.00 28.58  ? 294 PRO H CA  1 
ATOM   24411 C C   . PRO H 1 294 ? 12.388  -46.382 74.732  1.00 31.35  ? 294 PRO H C   1 
ATOM   24412 O O   . PRO H 1 294 ? 12.355  -45.611 75.693  1.00 27.51  ? 294 PRO H O   1 
ATOM   24413 C CB  . PRO H 1 294 ? 14.807  -45.916 74.068  1.00 33.01  ? 294 PRO H CB  1 
ATOM   24414 C CG  . PRO H 1 294 ? 15.378  -45.364 72.858  1.00 32.00  ? 294 PRO H CG  1 
ATOM   24415 C CD  . PRO H 1 294 ? 14.379  -44.303 72.473  1.00 34.48  ? 294 PRO H CD  1 
ATOM   24416 N N   . SER H 1 295 ? 11.556  -47.414 74.633  1.00 30.34  ? 295 SER H N   1 
ATOM   24417 C CA  . SER H 1 295 ? 10.926  -47.858 75.859  1.00 31.68  ? 295 SER H CA  1 
ATOM   24418 C C   . SER H 1 295 ? 11.987  -48.518 76.735  1.00 32.24  ? 295 SER H C   1 
ATOM   24419 O O   . SER H 1 295 ? 13.126  -48.735 76.316  1.00 37.81  ? 295 SER H O   1 
ATOM   24420 C CB  . SER H 1 295 ? 9.766   -48.814 75.579  1.00 30.19  ? 295 SER H CB  1 
ATOM   24421 O OG  . SER H 1 295 ? 10.175  -50.168 75.694  1.00 32.29  ? 295 SER H OG  1 
ATOM   24422 N N   . ARG H 1 296 ? 11.615  -48.823 77.968  1.00 32.67  ? 296 ARG H N   1 
ATOM   24423 C CA  . ARG H 1 296 ? 12.499  -49.511 78.899  1.00 37.82  ? 296 ARG H CA  1 
ATOM   24424 C C   . ARG H 1 296 ? 12.033  -50.948 79.114  1.00 37.31  ? 296 ARG H C   1 
ATOM   24425 O O   . ARG H 1 296 ? 12.178  -51.522 80.197  1.00 37.86  ? 296 ARG H O   1 
ATOM   24426 C CB  . ARG H 1 296 ? 12.594  -48.753 80.222  1.00 40.69  ? 296 ARG H CB  1 
ATOM   24427 C CG  . ARG H 1 296 ? 13.507  -47.518 80.145  1.00 48.09  ? 296 ARG H CG  1 
ATOM   24428 C CD  . ARG H 1 296 ? 14.891  -47.873 79.527  1.00 55.46  ? 296 ARG H CD  1 
ATOM   24429 N NE  . ARG H 1 296 ? 15.474  -49.063 80.144  1.00 61.31  ? 296 ARG H NE  1 
ATOM   24430 C CZ  . ARG H 1 296 ? 16.560  -49.697 79.720  1.00 55.54  ? 296 ARG H CZ  1 
ATOM   24431 N NH1 . ARG H 1 296 ? 17.207  -49.317 78.628  1.00 56.37  ? 296 ARG H NH1 1 
ATOM   24432 N NH2 . ARG H 1 296 ? 17.005  -50.743 80.410  1.00 60.29  ? 296 ARG H NH2 1 
ATOM   24433 N N   . SER H 1 297 ? 11.490  -51.555 78.060  1.00 29.97  ? 297 SER H N   1 
ATOM   24434 C CA  . SER H 1 297 ? 10.848  -52.854 78.188  1.00 33.49  ? 297 SER H CA  1 
ATOM   24435 C C   . SER H 1 297 ? 11.316  -53.853 77.140  1.00 33.31  ? 297 SER H C   1 
ATOM   24436 O O   . SER H 1 297 ? 10.642  -54.859 76.921  1.00 36.37  ? 297 SER H O   1 
ATOM   24437 C CB  . SER H 1 297 ? 9.332   -52.699 78.121  1.00 34.58  ? 297 SER H CB  1 
ATOM   24438 O OG  . SER H 1 297 ? 8.885   -51.910 79.204  1.00 37.33  ? 297 SER H OG  1 
ATOM   24439 N N   . GLU H 1 298 ? 12.457  -53.611 76.504  1.00 36.07  ? 298 GLU H N   1 
ATOM   24440 C CA  . GLU H 1 298 ? 13.052  -54.562 75.565  1.00 33.14  ? 298 GLU H CA  1 
ATOM   24441 C C   . GLU H 1 298 ? 13.906  -55.564 76.334  1.00 37.15  ? 298 GLU H C   1 
ATOM   24442 O O   . GLU H 1 298 ? 15.104  -55.358 76.522  1.00 42.02  ? 298 GLU H O   1 
ATOM   24443 C CB  . GLU H 1 298 ? 13.896  -53.835 74.528  1.00 31.02  ? 298 GLU H CB  1 
ATOM   24444 C CG  . GLU H 1 298 ? 13.105  -53.065 73.505  1.00 33.01  ? 298 GLU H CG  1 
ATOM   24445 C CD  . GLU H 1 298 ? 13.967  -52.206 72.611  1.00 35.23  ? 298 GLU H CD  1 
ATOM   24446 O OE1 . GLU H 1 298 ? 15.127  -52.601 72.336  1.00 41.75  ? 298 GLU H OE1 1 
ATOM   24447 O OE2 . GLU H 1 298 ? 13.470  -51.142 72.161  1.00 32.87  ? 298 GLU H OE2 1 
ATOM   24448 N N   . PHE H 1 299 ? 13.299  -56.671 76.777  1.00 35.19  ? 299 PHE H N   1 
ATOM   24449 C CA  . PHE H 1 299 ? 14.072  -57.812 77.270  1.00 37.81  ? 299 PHE H CA  1 
ATOM   24450 C C   . PHE H 1 299 ? 13.455  -59.105 76.736  1.00 36.40  ? 299 PHE H C   1 
ATOM   24451 O O   . PHE H 1 299 ? 12.415  -59.096 76.072  1.00 34.60  ? 299 PHE H O   1 
ATOM   24452 C CB  . PHE H 1 299 ? 14.182  -57.826 78.805  1.00 35.57  ? 299 PHE H CB  1 
ATOM   24453 C CG  . PHE H 1 299 ? 12.968  -57.305 79.521  1.00 35.10  ? 299 PHE H CG  1 
ATOM   24454 C CD1 . PHE H 1 299 ? 12.780  -55.946 79.707  1.00 37.41  ? 299 PHE H CD1 1 
ATOM   24455 C CD2 . PHE H 1 299 ? 12.030  -58.179 80.037  1.00 37.83  ? 299 PHE H CD2 1 
ATOM   24456 C CE1 . PHE H 1 299 ? 11.660  -55.466 80.385  1.00 41.86  ? 299 PHE H CE1 1 
ATOM   24457 C CE2 . PHE H 1 299 ? 10.912  -57.711 80.715  1.00 39.76  ? 299 PHE H CE2 1 
ATOM   24458 C CZ  . PHE H 1 299 ? 10.724  -56.356 80.889  1.00 36.95  ? 299 PHE H CZ  1 
ATOM   24459 N N   . GLU H 1 300 ? 14.105  -60.234 77.035  1.00 34.37  ? 300 GLU H N   1 
ATOM   24460 C CA  . GLU H 1 300 ? 13.684  -61.494 76.430  1.00 40.45  ? 300 GLU H CA  1 
ATOM   24461 C C   . GLU H 1 300 ? 12.216  -61.795 76.720  1.00 36.26  ? 300 GLU H C   1 
ATOM   24462 O O   . GLU H 1 300 ? 11.475  -62.202 75.819  1.00 33.64  ? 300 GLU H O   1 
ATOM   24463 C CB  . GLU H 1 300 ? 14.575  -62.643 76.908  1.00 40.11  ? 300 GLU H CB  1 
ATOM   24464 C CG  . GLU H 1 300 ? 14.915  -63.652 75.822  1.00 49.78  ? 300 GLU H CG  1 
ATOM   24465 C CD  . GLU H 1 300 ? 16.014  -63.168 74.856  1.00 61.68  ? 300 GLU H CD  1 
ATOM   24466 O OE1 . GLU H 1 300 ? 16.440  -61.987 74.932  1.00 54.69  ? 300 GLU H OE1 1 
ATOM   24467 O OE2 . GLU H 1 300 ? 16.448  -63.985 74.009  1.00 64.73  ? 300 GLU H OE2 1 
ATOM   24468 N N   . ALA H 1 301 ? 11.770  -61.584 77.962  1.00 34.09  ? 301 ALA H N   1 
ATOM   24469 C CA  . ALA H 1 301 ? 10.427  -62.013 78.332  1.00 36.05  ? 301 ALA H CA  1 
ATOM   24470 C C   . ALA H 1 301 ? 9.348   -61.194 77.635  1.00 34.51  ? 301 ALA H C   1 
ATOM   24471 O O   . ALA H 1 301 ? 8.180   -61.590 77.655  1.00 31.48  ? 301 ALA H O   1 
ATOM   24472 C CB  . ALA H 1 301 ? 10.243  -61.944 79.854  1.00 36.30  ? 301 ALA H CB  1 
ATOM   24473 N N   . THR H 1 302 ? 9.701   -60.060 77.032  1.00 34.02  ? 302 THR H N   1 
ATOM   24474 C CA  . THR H 1 302 ? 8.739   -59.294 76.249  1.00 29.04  ? 302 THR H CA  1 
ATOM   24475 C C   . THR H 1 302 ? 8.973   -59.409 74.752  1.00 26.33  ? 302 THR H C   1 
ATOM   24476 O O   . THR H 1 302 ? 8.016   -59.555 73.984  1.00 24.56  ? 302 THR H O   1 
ATOM   24477 C CB  . THR H 1 302 ? 8.783   -57.823 76.647  1.00 31.37  ? 302 THR H CB  1 
ATOM   24478 O OG1 . THR H 1 302 ? 10.133  -57.362 76.560  1.00 32.28  ? 302 THR H OG1 1 
ATOM   24479 C CG2 . THR H 1 302 ? 8.259   -57.641 78.075  1.00 30.27  ? 302 THR H CG2 1 
ATOM   24480 N N   . LEU H 1 303 ? 10.228  -59.352 74.313  1.00 29.31  ? 303 LEU H N   1 
ATOM   24481 C CA  . LEU H 1 303 ? 10.489  -59.392 72.879  1.00 26.84  ? 303 LEU H CA  1 
ATOM   24482 C C   . LEU H 1 303 ? 10.201  -60.773 72.302  1.00 25.74  ? 303 LEU H C   1 
ATOM   24483 O O   . LEU H 1 303 ? 9.652   -60.894 71.196  1.00 22.85  ? 303 LEU H O   1 
ATOM   24484 C CB  . LEU H 1 303 ? 11.929  -58.980 72.610  1.00 30.91  ? 303 LEU H CB  1 
ATOM   24485 C CG  . LEU H 1 303 ? 12.232  -57.521 72.932  1.00 29.67  ? 303 LEU H CG  1 
ATOM   24486 C CD1 . LEU H 1 303 ? 13.684  -57.395 73.330  1.00 30.58  ? 303 LEU H CD1 1 
ATOM   24487 C CD2 . LEU H 1 303 ? 11.914  -56.655 71.730  1.00 23.24  ? 303 LEU H CD2 1 
ATOM   24488 N N   . LYS H 1 304 ? 10.548  -61.830 73.043  1.00 23.96  ? 304 LYS H N   1 
ATOM   24489 C CA  . LYS H 1 304 ? 10.412  -63.176 72.483  1.00 28.91  ? 304 LYS H CA  1 
ATOM   24490 C C   . LYS H 1 304 ? 8.951   -63.580 72.275  1.00 24.40  ? 304 LYS H C   1 
ATOM   24491 O O   . LYS H 1 304 ? 8.614   -64.021 71.162  1.00 25.82  ? 304 LYS H O   1 
ATOM   24492 C CB  . LYS H 1 304 ? 11.193  -64.180 73.345  1.00 29.12  ? 304 LYS H CB  1 
ATOM   24493 C CG  . LYS H 1 304 ? 11.622  -65.453 72.614  1.00 37.65  ? 304 LYS H CG  1 
ATOM   24494 C CD  . LYS H 1 304 ? 11.800  -66.635 73.605  1.00 47.62  ? 304 LYS H CD  1 
ATOM   24495 C CE  . LYS H 1 304 ? 11.820  -68.004 72.898  1.00 50.26  ? 304 LYS H CE  1 
ATOM   24496 N NZ  . LYS H 1 304 ? 13.151  -68.710 72.944  1.00 40.24  ? 304 LYS H NZ  1 
ATOM   24497 N N   . PRO H 1 305 ? 8.042   -63.464 73.253  1.00 23.86  ? 305 PRO H N   1 
ATOM   24498 C CA  . PRO H 1 305 ? 6.635   -63.773 72.932  1.00 22.76  ? 305 PRO H CA  1 
ATOM   24499 C C   . PRO H 1 305 ? 6.054   -62.853 71.876  1.00 24.17  ? 305 PRO H C   1 
ATOM   24500 O O   . PRO H 1 305 ? 5.224   -63.294 71.066  1.00 21.34  ? 305 PRO H O   1 
ATOM   24501 C CB  . PRO H 1 305 ? 5.903   -63.623 74.274  1.00 20.06  ? 305 PRO H CB  1 
ATOM   24502 C CG  . PRO H 1 305 ? 6.922   -63.593 75.305  1.00 22.65  ? 305 PRO H CG  1 
ATOM   24503 C CD  . PRO H 1 305 ? 8.250   -63.254 74.697  1.00 23.50  ? 305 PRO H CD  1 
ATOM   24504 N N   . ALA H 1 306 ? 6.463   -61.579 71.866  1.00 23.51  ? 306 ALA H N   1 
ATOM   24505 C CA  . ALA H 1 306 ? 5.946   -60.645 70.867  1.00 22.55  ? 306 ALA H CA  1 
ATOM   24506 C C   . ALA H 1 306 ? 6.347   -61.076 69.460  1.00 21.52  ? 306 ALA H C   1 
ATOM   24507 O O   . ALA H 1 306 ? 5.520   -61.074 68.536  1.00 16.17  ? 306 ALA H O   1 
ATOM   24508 C CB  . ALA H 1 306 ? 6.443   -59.224 71.160  1.00 21.72  ? 306 ALA H CB  1 
ATOM   24509 N N   . GLU H 1 307 ? 7.626   -61.444 69.287  1.00 18.87  ? 307 GLU H N   1 
ATOM   24510 C CA  . GLU H 1 307 ? 8.123   -61.893 67.992  1.00 22.09  ? 307 GLU H CA  1 
ATOM   24511 C C   . GLU H 1 307 ? 7.360   -63.113 67.514  1.00 23.04  ? 307 GLU H C   1 
ATOM   24512 O O   . GLU H 1 307 ? 7.077   -63.246 66.315  1.00 19.21  ? 307 GLU H O   1 
ATOM   24513 C CB  . GLU H 1 307 ? 9.628   -62.218 68.070  1.00 22.03  ? 307 GLU H CB  1 
ATOM   24514 C CG  . GLU H 1 307 ? 10.212  -62.691 66.742  1.00 23.95  ? 307 GLU H CG  1 
ATOM   24515 C CD  . GLU H 1 307 ? 11.630  -63.285 66.844  1.00 33.36  ? 307 GLU H CD  1 
ATOM   24516 O OE1 . GLU H 1 307 ? 12.306  -63.111 67.881  1.00 36.81  ? 307 GLU H OE1 1 
ATOM   24517 O OE2 . GLU H 1 307 ? 12.062  -63.928 65.869  1.00 27.26  ? 307 GLU H OE2 1 
ATOM   24518 N N   . GLU H 1 308 ? 7.036   -64.029 68.438  1.00 21.92  ? 308 GLU H N   1 
ATOM   24519 C CA  . GLU H 1 308 ? 6.294   -65.222 68.042  1.00 23.21  ? 308 GLU H CA  1 
ATOM   24520 C C   . GLU H 1 308 ? 4.875   -64.867 67.619  1.00 23.24  ? 308 GLU H C   1 
ATOM   24521 O O   . GLU H 1 308 ? 4.360   -65.414 66.638  1.00 24.27  ? 308 GLU H O   1 
ATOM   24522 C CB  . GLU H 1 308 ? 6.273   -66.248 69.171  1.00 25.06  ? 308 GLU H CB  1 
ATOM   24523 C CG  . GLU H 1 308 ? 5.975   -67.656 68.672  1.00 36.59  ? 308 GLU H CG  1 
ATOM   24524 C CD  . GLU H 1 308 ? 5.356   -68.563 69.729  1.00 35.01  ? 308 GLU H CD  1 
ATOM   24525 O OE1 . GLU H 1 308 ? 4.978   -68.055 70.795  1.00 31.52  ? 308 GLU H OE1 1 
ATOM   24526 O OE2 . GLU H 1 308 ? 5.278   -69.792 69.497  1.00 40.20  ? 308 GLU H OE2 1 
ATOM   24527 N N   . PHE H 1 309 ? 4.231   -63.947 68.331  1.00 16.73  ? 309 PHE H N   1 
ATOM   24528 C CA  . PHE H 1 309 ? 2.883   -63.566 67.926  1.00 19.16  ? 309 PHE H CA  1 
ATOM   24529 C C   . PHE H 1 309 ? 2.913   -62.867 66.571  1.00 25.43  ? 309 PHE H C   1 
ATOM   24530 O O   . PHE H 1 309 ? 2.202   -63.265 65.637  1.00 21.38  ? 309 PHE H O   1 
ATOM   24531 C CB  . PHE H 1 309 ? 2.241   -62.673 68.985  1.00 17.37  ? 309 PHE H CB  1 
ATOM   24532 C CG  . PHE H 1 309 ? 0.776   -62.422 68.742  1.00 21.46  ? 309 PHE H CG  1 
ATOM   24533 C CD1 . PHE H 1 309 ? 0.359   -61.379 67.921  1.00 17.02  ? 309 PHE H CD1 1 
ATOM   24534 C CD2 . PHE H 1 309 ? -0.173  -63.242 69.316  1.00 21.30  ? 309 PHE H CD2 1 
ATOM   24535 C CE1 . PHE H 1 309 ? -0.975  -61.162 67.666  1.00 15.61  ? 309 PHE H CE1 1 
ATOM   24536 C CE2 . PHE H 1 309 ? -1.518  -63.027 69.087  1.00 22.70  ? 309 PHE H CE2 1 
ATOM   24537 C CZ  . PHE H 1 309 ? -1.919  -61.981 68.259  1.00 24.46  ? 309 PHE H CZ  1 
ATOM   24538 N N   . ILE H 1 310 ? 3.752   -61.826 66.454  1.00 21.25  ? 310 ILE H N   1 
ATOM   24539 C CA  . ILE H 1 310 ? 3.896   -61.085 65.206  1.00 24.31  ? 310 ILE H CA  1 
ATOM   24540 C C   . ILE H 1 310 ? 4.255   -62.025 64.058  1.00 21.65  ? 310 ILE H C   1 
ATOM   24541 O O   . ILE H 1 310 ? 3.797   -61.841 62.926  1.00 19.84  ? 310 ILE H O   1 
ATOM   24542 C CB  . ILE H 1 310 ? 4.937   -59.958 65.373  1.00 19.77  ? 310 ILE H CB  1 
ATOM   24543 C CG1 . ILE H 1 310 ? 4.378   -58.847 66.281  1.00 21.96  ? 310 ILE H CG1 1 
ATOM   24544 C CG2 . ILE H 1 310 ? 5.305   -59.367 64.032  1.00 21.03  ? 310 ILE H CG2 1 
ATOM   24545 C CD1 . ILE H 1 310 ? 2.945   -58.433 65.932  1.00 21.48  ? 310 ILE H CD1 1 
ATOM   24546 N N   . GLU H 1 311 ? 5.066   -63.052 64.323  1.00 20.23  ? 311 GLU H N   1 
ATOM   24547 C CA  . GLU H 1 311 ? 5.414   -63.965 63.232  1.00 26.51  ? 311 GLU H CA  1 
ATOM   24548 C C   . GLU H 1 311 ? 4.205   -64.750 62.747  1.00 24.41  ? 311 GLU H C   1 
ATOM   24549 O O   . GLU H 1 311 ? 4.104   -65.078 61.563  1.00 25.80  ? 311 GLU H O   1 
ATOM   24550 C CB  . GLU H 1 311 ? 6.507   -64.944 63.647  1.00 24.12  ? 311 GLU H CB  1 
ATOM   24551 C CG  . GLU H 1 311 ? 7.166   -65.592 62.429  1.00 30.06  ? 311 GLU H CG  1 
ATOM   24552 C CD  . GLU H 1 311 ? 7.956   -64.580 61.595  1.00 31.60  ? 311 GLU H CD  1 
ATOM   24553 O OE1 . GLU H 1 311 ? 8.737   -63.809 62.193  1.00 32.68  ? 311 GLU H OE1 1 
ATOM   24554 O OE2 . GLU H 1 311 ? 7.825   -64.572 60.352  1.00 34.05  ? 311 GLU H OE2 1 
ATOM   24555 N N   . MET H 1 312 ? 3.303   -65.092 63.654  1.00 25.34  ? 312 MET H N   1 
ATOM   24556 C CA  . MET H 1 312 ? 2.074   -65.749 63.258  1.00 26.34  ? 312 MET H CA  1 
ATOM   24557 C C   . MET H 1 312 ? 1.189   -64.812 62.442  1.00 25.71  ? 312 MET H C   1 
ATOM   24558 O O   . MET H 1 312 ? 0.497   -65.253 61.517  1.00 23.05  ? 312 MET H O   1 
ATOM   24559 C CB  . MET H 1 312 ? 1.358   -66.248 64.509  1.00 20.14  ? 312 MET H CB  1 
ATOM   24560 C CG  . MET H 1 312 ? 0.220   -67.133 64.215  1.00 26.00  ? 312 MET H CG  1 
ATOM   24561 S SD  . MET H 1 312 ? -1.216  -66.087 64.125  1.00 50.10  ? 312 MET H SD  1 
ATOM   24562 C CE  . MET H 1 312 ? -0.860  -64.838 65.393  1.00 34.91  ? 312 MET H CE  1 
ATOM   24563 N N   . ILE H 1 313 ? 1.173   -63.520 62.793  1.00 22.53  ? 313 ILE H N   1 
ATOM   24564 C CA  . ILE H 1 313 ? 0.408   -62.543 62.019  1.00 23.02  ? 313 ILE H CA  1 
ATOM   24565 C C   . ILE H 1 313 ? 0.934   -62.498 60.594  1.00 21.54  ? 313 ILE H C   1 
ATOM   24566 O O   . ILE H 1 313 ? 0.168   -62.439 59.633  1.00 21.55  ? 313 ILE H O   1 
ATOM   24567 C CB  . ILE H 1 313 ? 0.471   -61.152 62.691  1.00 25.12  ? 313 ILE H CB  1 
ATOM   24568 C CG1 . ILE H 1 313 ? -0.285  -61.135 64.028  1.00 24.91  ? 313 ILE H CG1 1 
ATOM   24569 C CG2 . ILE H 1 313 ? -0.114  -60.087 61.785  1.00 16.82  ? 313 ILE H CG2 1 
ATOM   24570 C CD1 . ILE H 1 313 ? -1.827  -61.209 63.849  1.00 21.78  ? 313 ILE H CD1 1 
ATOM   24571 N N   . ARG H 1 314 ? 2.254   -62.557 60.437  1.00 20.36  ? 314 ARG H N   1 
ATOM   24572 C CA  . ARG H 1 314 ? 2.830   -62.566 59.100  1.00 24.17  ? 314 ARG H CA  1 
ATOM   24573 C C   . ARG H 1 314 ? 2.484   -63.858 58.373  1.00 25.64  ? 314 ARG H C   1 
ATOM   24574 O O   . ARG H 1 314 ? 2.234   -63.845 57.161  1.00 23.79  ? 314 ARG H O   1 
ATOM   24575 C CB  . ARG H 1 314 ? 4.347   -62.381 59.176  1.00 20.02  ? 314 ARG H CB  1 
ATOM   24576 C CG  . ARG H 1 314 ? 4.951   -61.925 57.875  1.00 23.94  ? 314 ARG H CG  1 
ATOM   24577 C CD  . ARG H 1 314 ? 6.453   -61.656 57.988  1.00 22.98  ? 314 ARG H CD  1 
ATOM   24578 N NE  . ARG H 1 314 ? 7.240   -62.870 58.169  1.00 24.37  ? 314 ARG H NE  1 
ATOM   24579 C CZ  . ARG H 1 314 ? 7.730   -63.614 57.183  1.00 26.44  ? 314 ARG H CZ  1 
ATOM   24580 N NH1 . ARG H 1 314 ? 7.515   -63.312 55.914  1.00 25.52  ? 314 ARG H NH1 1 
ATOM   24581 N NH2 . ARG H 1 314 ? 8.464   -64.685 57.481  1.00 31.37  ? 314 ARG H NH2 1 
ATOM   24582 N N   . THR H 1 315 ? 2.468   -64.980 59.100  1.00 20.47  ? 315 THR H N   1 
ATOM   24583 C CA  . THR H 1 315 ? 2.033   -66.244 58.512  1.00 25.11  ? 315 THR H CA  1 
ATOM   24584 C C   . THR H 1 315 ? 0.588   -66.169 58.028  1.00 25.16  ? 315 THR H C   1 
ATOM   24585 O O   . THR H 1 315 ? 0.269   -66.666 56.944  1.00 26.40  ? 315 THR H O   1 
ATOM   24586 C CB  . THR H 1 315 ? 2.196   -67.373 59.524  1.00 25.64  ? 315 THR H CB  1 
ATOM   24587 O OG1 . THR H 1 315 ? 3.574   -67.493 59.881  1.00 29.60  ? 315 THR H OG1 1 
ATOM   24588 C CG2 . THR H 1 315 ? 1.701   -68.692 58.942  1.00 26.59  ? 315 THR H CG2 1 
ATOM   24589 N N   . ILE H 1 316 ? -0.303  -65.567 58.824  1.00 24.40  ? 316 ILE H N   1 
ATOM   24590 C CA  . ILE H 1 316 ? -1.692  -65.383 58.399  1.00 22.86  ? 316 ILE H CA  1 
ATOM   24591 C C   . ILE H 1 316 ? -1.740  -64.677 57.049  1.00 25.65  ? 316 ILE H C   1 
ATOM   24592 O O   . ILE H 1 316 ? -2.597  -64.975 56.212  1.00 28.62  ? 316 ILE H O   1 
ATOM   24593 C CB  . ILE H 1 316 ? -2.491  -64.604 59.469  1.00 26.95  ? 316 ILE H CB  1 
ATOM   24594 C CG1 . ILE H 1 316 ? -2.678  -65.401 60.759  1.00 25.99  ? 316 ILE H CG1 1 
ATOM   24595 C CG2 . ILE H 1 316 ? -3.845  -64.173 58.932  1.00 28.37  ? 316 ILE H CG2 1 
ATOM   24596 C CD1 . ILE H 1 316 ? -2.738  -66.879 60.584  1.00 29.59  ? 316 ILE H CD1 1 
ATOM   24597 N N   . GLY H 1 317 ? -0.824  -63.726 56.812  1.00 27.77  ? 317 GLY H N   1 
ATOM   24598 C CA  . GLY H 1 317 ? -0.731  -63.040 55.526  1.00 21.40  ? 317 GLY H CA  1 
ATOM   24599 C C   . GLY H 1 317 ? -0.734  -61.521 55.558  1.00 26.20  ? 317 GLY H C   1 
ATOM   24600 O O   . GLY H 1 317 ? -0.839  -60.863 54.518  1.00 24.99  ? 317 GLY H O   1 
ATOM   24601 N N   . TYR H 1 318 ? -0.617  -60.930 56.739  1.00 25.39  ? 318 TYR H N   1 
ATOM   24602 C CA  . TYR H 1 318 ? -0.665  -59.485 56.823  1.00 22.14  ? 318 TYR H CA  1 
ATOM   24603 C C   . TYR H 1 318 ? 0.658   -58.881 56.361  1.00 23.40  ? 318 TYR H C   1 
ATOM   24604 O O   . TYR H 1 318 ? 1.736   -59.365 56.718  1.00 21.79  ? 318 TYR H O   1 
ATOM   24605 C CB  . TYR H 1 318 ? -0.989  -59.043 58.251  1.00 22.34  ? 318 TYR H CB  1 
ATOM   24606 C CG  . TYR H 1 318 ? -0.921  -57.561 58.373  1.00 22.46  ? 318 TYR H CG  1 
ATOM   24607 C CD1 . TYR H 1 318 ? -1.845  -56.758 57.731  1.00 22.33  ? 318 TYR H CD1 1 
ATOM   24608 C CD2 . TYR H 1 318 ? 0.122   -56.955 59.052  1.00 22.73  ? 318 TYR H CD2 1 
ATOM   24609 C CE1 . TYR H 1 318 ? -1.758  -55.380 57.815  1.00 24.90  ? 318 TYR H CE1 1 
ATOM   24610 C CE2 . TYR H 1 318 ? 0.224   -55.581 59.136  1.00 19.43  ? 318 TYR H CE2 1 
ATOM   24611 C CZ  . TYR H 1 318 ? -0.712  -54.797 58.519  1.00 23.22  ? 318 TYR H CZ  1 
ATOM   24612 O OH  . TYR H 1 318 ? -0.600  -53.420 58.605  1.00 23.17  ? 318 TYR H OH  1 
ATOM   24613 N N   . ARG H 1 319 ? 0.581   -57.832 55.554  1.00 22.91  ? 319 ARG H N   1 
ATOM   24614 C CA  . ARG H 1 319 ? 1.777   -57.134 55.100  1.00 26.37  ? 319 ARG H CA  1 
ATOM   24615 C C   . ARG H 1 319 ? 1.592   -55.653 55.386  1.00 21.61  ? 319 ARG H C   1 
ATOM   24616 O O   . ARG H 1 319 ? 0.523   -55.098 55.125  1.00 21.13  ? 319 ARG H O   1 
ATOM   24617 C CB  . ARG H 1 319 ? 2.050   -57.369 53.601  1.00 25.02  ? 319 ARG H CB  1 
ATOM   24618 C CG  . ARG H 1 319 ? 2.161   -58.845 53.151  1.00 23.37  ? 319 ARG H CG  1 
ATOM   24619 C CD  . ARG H 1 319 ? 3.464   -59.523 53.576  1.00 22.17  ? 319 ARG H CD  1 
ATOM   24620 N NE  . ARG H 1 319 ? 3.425   -60.961 53.293  1.00 27.01  ? 319 ARG H NE  1 
ATOM   24621 C CZ  . ARG H 1 319 ? 3.043   -61.885 54.167  1.00 24.81  ? 319 ARG H CZ  1 
ATOM   24622 N NH1 . ARG H 1 319 ? 2.637   -61.561 55.382  1.00 21.70  ? 319 ARG H NH1 1 
ATOM   24623 N NH2 . ARG H 1 319 ? 3.070   -63.166 53.812  1.00 27.45  ? 319 ARG H NH2 1 
ATOM   24624 N N   . GLY H 1 320 ? 2.622   -55.018 55.931  1.00 24.08  ? 320 GLY H N   1 
ATOM   24625 C CA  . GLY H 1 320 ? 2.523   -53.629 56.334  1.00 22.88  ? 320 GLY H CA  1 
ATOM   24626 C C   . GLY H 1 320 ? 2.907   -53.486 57.787  1.00 21.31  ? 320 GLY H C   1 
ATOM   24627 O O   . GLY H 1 320 ? 3.515   -54.388 58.372  1.00 21.04  ? 320 GLY H O   1 
ATOM   24628 N N   . TYR H 1 321 ? 2.551   -52.352 58.389  1.00 16.86  ? 321 TYR H N   1 
ATOM   24629 C CA  . TYR H 1 321 ? 2.943   -52.078 59.767  1.00 20.97  ? 321 TYR H CA  1 
ATOM   24630 C C   . TYR H 1 321 ? 1.934   -52.645 60.771  1.00 22.67  ? 321 TYR H C   1 
ATOM   24631 O O   . TYR H 1 321 ? 0.727   -52.621 60.538  1.00 18.74  ? 321 TYR H O   1 
ATOM   24632 C CB  . TYR H 1 321 ? 3.120   -50.578 59.964  1.00 21.46  ? 321 TYR H CB  1 
ATOM   24633 C CG  . TYR H 1 321 ? 4.209   -50.010 59.080  1.00 21.55  ? 321 TYR H CG  1 
ATOM   24634 C CD1 . TYR H 1 321 ? 3.936   -49.590 57.789  1.00 23.45  ? 321 TYR H CD1 1 
ATOM   24635 C CD2 . TYR H 1 321 ? 5.518   -49.926 59.533  1.00 21.03  ? 321 TYR H CD2 1 
ATOM   24636 C CE1 . TYR H 1 321 ? 4.947   -49.079 56.978  1.00 23.50  ? 321 TYR H CE1 1 
ATOM   24637 C CE2 . TYR H 1 321 ? 6.524   -49.423 58.741  1.00 19.02  ? 321 TYR H CE2 1 
ATOM   24638 C CZ  . TYR H 1 321 ? 6.230   -49.001 57.468  1.00 20.35  ? 321 TYR H CZ  1 
ATOM   24639 O OH  . TYR H 1 321 ? 7.219   -48.496 56.678  1.00 25.82  ? 321 TYR H OH  1 
ATOM   24640 N N   . VAL H 1 322 ? 2.454   -53.193 61.878  1.00 17.58  ? 322 VAL H N   1 
ATOM   24641 C CA  . VAL H 1 322 ? 1.643   -53.741 62.956  1.00 20.84  ? 322 VAL H CA  1 
ATOM   24642 C C   . VAL H 1 322 ? 2.370   -53.444 64.259  1.00 20.67  ? 322 VAL H C   1 
ATOM   24643 O O   . VAL H 1 322 ? 3.601   -53.397 64.302  1.00 21.06  ? 322 VAL H O   1 
ATOM   24644 C CB  . VAL H 1 322 ? 1.403   -55.267 62.794  1.00 21.26  ? 322 VAL H CB  1 
ATOM   24645 C CG1 . VAL H 1 322 ? 2.714   -56.009 62.845  1.00 14.60  ? 322 VAL H CG1 1 
ATOM   24646 C CG2 . VAL H 1 322 ? 0.450   -55.799 63.874  1.00 17.83  ? 322 VAL H CG2 1 
ATOM   24647 N N   . ASN H 1 323 ? 1.613   -53.232 65.326  1.00 20.28  ? 323 ASN H N   1 
ATOM   24648 C CA  . ASN H 1 323 ? 2.233   -53.004 66.622  1.00 19.33  ? 323 ASN H CA  1 
ATOM   24649 C C   . ASN H 1 323 ? 1.467   -53.775 67.686  1.00 22.90  ? 323 ASN H C   1 
ATOM   24650 O O   . ASN H 1 323 ? 0.284   -54.066 67.519  1.00 22.28  ? 323 ASN H O   1 
ATOM   24651 C CB  . ASN H 1 323 ? 2.283   -51.509 66.960  1.00 23.02  ? 323 ASN H CB  1 
ATOM   24652 C CG  . ASN H 1 323 ? 0.899   -50.886 67.079  1.00 26.36  ? 323 ASN H CG  1 
ATOM   24653 O OD1 . ASN H 1 323 ? 0.349   -50.329 66.108  1.00 25.65  ? 323 ASN H OD1 1 
ATOM   24654 N ND2 . ASN H 1 323 ? 0.335   -50.963 68.273  1.00 29.24  ? 323 ASN H ND2 1 
ATOM   24655 N N   . ILE H 1 324 ? 2.148   -54.102 68.785  1.00 20.61  ? 324 ILE H N   1 
ATOM   24656 C CA  . ILE H 1 324 ? 1.557   -54.879 69.869  1.00 23.51  ? 324 ILE H CA  1 
ATOM   24657 C C   . ILE H 1 324 ? 1.802   -54.139 71.182  1.00 24.57  ? 324 ILE H C   1 
ATOM   24658 O O   . ILE H 1 324 ? 2.894   -53.612 71.395  1.00 22.58  ? 324 ILE H O   1 
ATOM   24659 C CB  . ILE H 1 324 ? 2.126   -56.315 69.892  1.00 20.91  ? 324 ILE H CB  1 
ATOM   24660 C CG1 . ILE H 1 324 ? 1.402   -57.206 70.901  1.00 24.92  ? 324 ILE H CG1 1 
ATOM   24661 C CG2 . ILE H 1 324 ? 3.637   -56.323 70.149  1.00 22.86  ? 324 ILE H CG2 1 
ATOM   24662 C CD1 . ILE H 1 324 ? 1.790   -58.709 70.775  1.00 22.48  ? 324 ILE H CD1 1 
ATOM   24663 N N   . ASP H 1 325 ? 0.770   -54.065 72.030  1.00 25.67  ? 325 ASP H N   1 
ATOM   24664 C CA  . ASP H 1 325 ? 0.782   -53.409 73.341  1.00 29.95  ? 325 ASP H CA  1 
ATOM   24665 C C   . ASP H 1 325 ? 0.987   -54.437 74.441  1.00 27.51  ? 325 ASP H C   1 
ATOM   24666 O O   . ASP H 1 325 ? 0.418   -55.532 74.386  1.00 31.49  ? 325 ASP H O   1 
ATOM   24667 C CB  . ASP H 1 325 ? -0.551  -52.709 73.666  1.00 31.55  ? 325 ASP H CB  1 
ATOM   24668 C CG  . ASP H 1 325 ? -0.745  -51.416 72.937  1.00 45.19  ? 325 ASP H CG  1 
ATOM   24669 O OD1 . ASP H 1 325 ? 0.217   -50.618 72.878  1.00 51.00  ? 325 ASP H OD1 1 
ATOM   24670 O OD2 . ASP H 1 325 ? -1.887  -51.161 72.477  1.00 48.58  ? 325 ASP H OD2 1 
ATOM   24671 N N   . GLY H 1 326 ? 1.701   -54.042 75.489  1.00 27.30  ? 326 GLY H N   1 
ATOM   24672 C CA  . GLY H 1 326 ? 1.934   -54.913 76.621  1.00 24.82  ? 326 GLY H CA  1 
ATOM   24673 C C   . GLY H 1 326 ? 2.197   -54.127 77.882  1.00 26.03  ? 326 GLY H C   1 
ATOM   24674 O O   . GLY H 1 326 ? 2.259   -52.895 77.873  1.00 27.03  ? 326 GLY H O   1 
ATOM   24675 N N   . ILE H 1 327 ? 2.345   -54.859 78.989  1.00 32.24  ? 327 ILE H N   1 
ATOM   24676 C CA  . ILE H 1 327 ? 2.763   -54.279 80.260  1.00 31.98  ? 327 ILE H CA  1 
ATOM   24677 C C   . ILE H 1 327 ? 3.712   -55.236 80.970  1.00 31.33  ? 327 ILE H C   1 
ATOM   24678 O O   . ILE H 1 327 ? 3.709   -56.447 80.735  1.00 33.67  ? 327 ILE H O   1 
ATOM   24679 C CB  . ILE H 1 327 ? 1.574   -53.944 81.198  1.00 37.47  ? 327 ILE H CB  1 
ATOM   24680 C CG1 . ILE H 1 327 ? 0.865   -55.224 81.667  1.00 35.69  ? 327 ILE H CG1 1 
ATOM   24681 C CG2 . ILE H 1 327 ? 0.602   -52.968 80.536  1.00 36.18  ? 327 ILE H CG2 1 
ATOM   24682 C CD1 . ILE H 1 327 ? -0.441  -54.959 82.397  1.00 34.54  ? 327 ILE H CD1 1 
ATOM   24683 N N   . VAL H 1 328 ? 4.530   -54.675 81.856  1.00 32.36  ? 328 VAL H N   1 
ATOM   24684 C CA  . VAL H 1 328 ? 5.339   -55.456 82.787  1.00 37.13  ? 328 VAL H CA  1 
ATOM   24685 C C   . VAL H 1 328 ? 4.943   -55.053 84.201  1.00 42.58  ? 328 VAL H C   1 
ATOM   24686 O O   . VAL H 1 328 ? 4.988   -53.867 84.551  1.00 41.79  ? 328 VAL H O   1 
ATOM   24687 C CB  . VAL H 1 328 ? 6.842   -55.258 82.556  1.00 41.06  ? 328 VAL H CB  1 
ATOM   24688 C CG1 . VAL H 1 328 ? 7.645   -56.061 83.588  1.00 37.73  ? 328 VAL H CG1 1 
ATOM   24689 C CG2 . VAL H 1 328 ? 7.208   -55.655 81.122  1.00 34.53  ? 328 VAL H CG2 1 
ATOM   24690 N N   . LEU H 1 329 ? 4.538   -56.038 85.003  1.00 50.29  ? 329 LEU H N   1 
ATOM   24691 C CA  . LEU H 1 329 ? 4.048   -55.795 86.353  1.00 52.22  ? 329 LEU H CA  1 
ATOM   24692 C C   . LEU H 1 329 ? 5.210   -55.553 87.310  1.00 52.51  ? 329 LEU H C   1 
ATOM   24693 O O   . LEU H 1 329 ? 6.347   -55.962 87.061  1.00 46.50  ? 329 LEU H O   1 
ATOM   24694 C CB  . LEU H 1 329 ? 3.203   -56.973 86.847  1.00 49.08  ? 329 LEU H CB  1 
ATOM   24695 C CG  . LEU H 1 329 ? 1.817   -57.158 86.219  1.00 48.97  ? 329 LEU H CG  1 
ATOM   24696 C CD1 . LEU H 1 329 ? 0.839   -57.759 87.218  1.00 47.56  ? 329 LEU H CD1 1 
ATOM   24697 C CD2 . LEU H 1 329 ? 1.283   -55.843 85.688  1.00 45.40  ? 329 LEU H CD2 1 
ATOM   24698 N N   . ASP H 1 330 ? 4.904   -54.868 88.420  1.00 59.29  ? 330 ASP H N   1 
ATOM   24699 C CA  . ASP H 1 330 ? 5.913   -54.638 89.450  1.00 60.02  ? 330 ASP H CA  1 
ATOM   24700 C C   . ASP H 1 330 ? 6.540   -55.947 89.904  1.00 57.19  ? 330 ASP H C   1 
ATOM   24701 O O   . ASP H 1 330 ? 7.728   -55.987 90.242  1.00 62.58  ? 330 ASP H O   1 
ATOM   24702 C CB  . ASP H 1 330 ? 5.302   -53.888 90.636  1.00 63.29  ? 330 ASP H CB  1 
ATOM   24703 C CG  . ASP H 1 330 ? 5.528   -52.379 90.554  1.00 72.52  ? 330 ASP H CG  1 
ATOM   24704 O OD1 . ASP H 1 330 ? 6.656   -51.925 90.855  1.00 73.40  ? 330 ASP H OD1 1 
ATOM   24705 O OD2 . ASP H 1 330 ? 4.580   -51.644 90.198  1.00 72.72  ? 330 ASP H OD2 1 
ATOM   24706 N N   . ASP H 1 331 ? 5.776   -57.026 89.882  1.00 58.33  ? 331 ASP H N   1 
ATOM   24707 C CA  . ASP H 1 331 ? 6.304   -58.361 90.111  1.00 53.93  ? 331 ASP H CA  1 
ATOM   24708 C C   . ASP H 1 331 ? 6.870   -59.006 88.844  1.00 57.17  ? 331 ASP H C   1 
ATOM   24709 O O   . ASP H 1 331 ? 7.179   -60.204 88.864  1.00 56.06  ? 331 ASP H O   1 
ATOM   24710 C CB  . ASP H 1 331 ? 5.205   -59.245 90.695  1.00 56.55  ? 331 ASP H CB  1 
ATOM   24711 C CG  . ASP H 1 331 ? 3.889   -59.062 89.980  1.00 61.20  ? 331 ASP H CG  1 
ATOM   24712 O OD1 . ASP H 1 331 ? 3.150   -58.106 90.327  1.00 65.35  ? 331 ASP H OD1 1 
ATOM   24713 O OD2 . ASP H 1 331 ? 3.613   -59.859 89.054  1.00 56.51  ? 331 ASP H OD2 1 
ATOM   24714 N N   . GLY H 1 332 ? 6.985   -58.265 87.741  1.00 56.13  ? 332 GLY H N   1 
ATOM   24715 C CA  . GLY H 1 332 ? 7.710   -58.744 86.579  1.00 45.27  ? 332 GLY H CA  1 
ATOM   24716 C C   . GLY H 1 332 ? 6.986   -59.723 85.683  1.00 48.77  ? 332 GLY H C   1 
ATOM   24717 O O   . GLY H 1 332 ? 7.631   -60.328 84.817  1.00 44.22  ? 332 GLY H O   1 
ATOM   24718 N N   . ARG H 1 333 ? 5.679   -59.918 85.855  1.00 50.30  ? 333 ARG H N   1 
ATOM   24719 C CA  . ARG H 1 333 ? 4.924   -60.686 84.872  1.00 46.51  ? 333 ARG H CA  1 
ATOM   24720 C C   . ARG H 1 333 ? 4.594   -59.812 83.666  1.00 37.15  ? 333 ARG H C   1 
ATOM   24721 O O   . ARG H 1 333 ? 4.401   -58.601 83.779  1.00 38.11  ? 333 ARG H O   1 
ATOM   24722 C CB  . ARG H 1 333 ? 3.626   -61.253 85.459  1.00 45.65  ? 333 ARG H CB  1 
ATOM   24723 C CG  . ARG H 1 333 ? 3.751   -61.959 86.796  1.00 48.58  ? 333 ARG H CG  1 
ATOM   24724 C CD  . ARG H 1 333 ? 2.376   -62.320 87.348  1.00 44.68  ? 333 ARG H CD  1 
ATOM   24725 N NE  . ARG H 1 333 ? 1.862   -61.304 88.264  1.00 48.11  ? 333 ARG H NE  1 
ATOM   24726 C CZ  . ARG H 1 333 ? 0.587   -61.199 88.609  1.00 46.56  ? 333 ARG H CZ  1 
ATOM   24727 N NH1 . ARG H 1 333 ? -0.326  -62.020 88.122  1.00 50.30  ? 333 ARG H NH1 1 
ATOM   24728 N NH2 . ARG H 1 333 ? 0.217   -60.246 89.461  1.00 46.14  ? 333 ARG H NH2 1 
ATOM   24729 N N   . VAL H 1 334 ? 4.521   -60.450 82.508  1.00 34.52  ? 334 VAL H N   1 
ATOM   24730 C CA  . VAL H 1 334 ? 4.277   -59.788 81.237  1.00 35.13  ? 334 VAL H CA  1 
ATOM   24731 C C   . VAL H 1 334 ? 2.868   -60.132 80.763  1.00 32.79  ? 334 VAL H C   1 
ATOM   24732 O O   . VAL H 1 334 ? 2.407   -61.268 80.920  1.00 34.76  ? 334 VAL H O   1 
ATOM   24733 C CB  . VAL H 1 334 ? 5.339   -60.209 80.201  1.00 33.32  ? 334 VAL H CB  1 
ATOM   24734 C CG1 . VAL H 1 334 ? 5.100   -59.511 78.864  1.00 28.16  ? 334 VAL H CG1 1 
ATOM   24735 C CG2 . VAL H 1 334 ? 6.727   -59.910 80.736  1.00 25.68  ? 334 VAL H CG2 1 
ATOM   24736 N N   . PHE H 1 335 ? 2.178   -59.139 80.211  1.00 32.06  ? 335 PHE H N   1 
ATOM   24737 C CA  . PHE H 1 335 ? 0.894   -59.329 79.557  1.00 27.04  ? 335 PHE H CA  1 
ATOM   24738 C C   . PHE H 1 335 ? 0.876   -58.479 78.303  1.00 29.57  ? 335 PHE H C   1 
ATOM   24739 O O   . PHE H 1 335 ? 1.311   -57.325 78.337  1.00 29.03  ? 335 PHE H O   1 
ATOM   24740 C CB  . PHE H 1 335 ? -0.282  -58.910 80.441  1.00 30.91  ? 335 PHE H CB  1 
ATOM   24741 C CG  . PHE H 1 335 ? -0.513  -59.792 81.636  1.00 35.63  ? 335 PHE H CG  1 
ATOM   24742 C CD1 . PHE H 1 335 ? -1.008  -61.077 81.483  1.00 35.04  ? 335 PHE H CD1 1 
ATOM   24743 C CD2 . PHE H 1 335 ? -0.294  -59.307 82.924  1.00 36.71  ? 335 PHE H CD2 1 
ATOM   24744 C CE1 . PHE H 1 335 ? -1.252  -61.885 82.606  1.00 40.64  ? 335 PHE H CE1 1 
ATOM   24745 C CE2 . PHE H 1 335 ? -0.536  -60.105 84.042  1.00 37.67  ? 335 PHE H CE2 1 
ATOM   24746 C CZ  . PHE H 1 335 ? -1.007  -61.393 83.885  1.00 34.41  ? 335 PHE H CZ  1 
ATOM   24747 N N   . PHE H 1 336 ? 0.380   -59.045 77.202  1.00 29.88  ? 336 PHE H N   1 
ATOM   24748 C CA  . PHE H 1 336 ? 0.093   -58.279 75.997  1.00 24.06  ? 336 PHE H CA  1 
ATOM   24749 C C   . PHE H 1 336 ? -1.408  -58.038 75.879  1.00 26.47  ? 336 PHE H C   1 
ATOM   24750 O O   . PHE H 1 336 ? -2.228  -58.849 76.326  1.00 26.15  ? 336 PHE H O   1 
ATOM   24751 C CB  . PHE H 1 336 ? 0.629   -58.983 74.750  1.00 20.82  ? 336 PHE H CB  1 
ATOM   24752 C CG  . PHE H 1 336 ? 2.112   -59.129 74.755  1.00 26.50  ? 336 PHE H CG  1 
ATOM   24753 C CD1 . PHE H 1 336 ? 2.925   -58.079 74.363  1.00 26.85  ? 336 PHE H CD1 1 
ATOM   24754 C CD2 . PHE H 1 336 ? 2.705   -60.298 75.219  1.00 26.60  ? 336 PHE H CD2 1 
ATOM   24755 C CE1 . PHE H 1 336 ? 4.308   -58.216 74.391  1.00 32.27  ? 336 PHE H CE1 1 
ATOM   24756 C CE2 . PHE H 1 336 ? 4.087   -60.445 75.255  1.00 24.51  ? 336 PHE H CE2 1 
ATOM   24757 C CZ  . PHE H 1 336 ? 4.889   -59.407 74.836  1.00 29.43  ? 336 PHE H CZ  1 
ATOM   24758 N N   . HIS H 1 337 ? -1.755  -56.895 75.273  1.00 27.18  ? 337 HIS H N   1 
ATOM   24759 C CA  . HIS H 1 337 ? -3.087  -56.307 75.348  1.00 25.23  ? 337 HIS H CA  1 
ATOM   24760 C C   . HIS H 1 337 ? -3.814  -56.252 74.018  1.00 26.43  ? 337 HIS H C   1 
ATOM   24761 O O   . HIS H 1 337 ? -5.022  -56.460 73.990  1.00 22.63  ? 337 HIS H O   1 
ATOM   24762 C CB  . HIS H 1 337 ? -3.007  -54.874 75.905  1.00 27.83  ? 337 HIS H CB  1 
ATOM   24763 C CG  . HIS H 1 337 ? -2.896  -54.800 77.395  1.00 30.28  ? 337 HIS H CG  1 
ATOM   24764 N ND1 . HIS H 1 337 ? -3.543  -55.680 78.237  1.00 34.04  ? 337 HIS H ND1 1 
ATOM   24765 C CD2 . HIS H 1 337 ? -2.237  -53.928 78.195  1.00 32.14  ? 337 HIS H CD2 1 
ATOM   24766 C CE1 . HIS H 1 337 ? -3.281  -55.358 79.492  1.00 35.62  ? 337 HIS H CE1 1 
ATOM   24767 N NE2 . HIS H 1 337 ? -2.497  -54.294 79.495  1.00 36.69  ? 337 HIS H NE2 1 
ATOM   24768 N N   . GLU H 1 338 ? -3.124  -55.932 72.924  1.00 26.61  ? 338 GLU H N   1 
ATOM   24769 C CA  . GLU H 1 338 ? -3.788  -55.727 71.642  1.00 28.35  ? 338 GLU H CA  1 
ATOM   24770 C C   . GLU H 1 338 ? -2.749  -55.567 70.536  1.00 30.51  ? 338 GLU H C   1 
ATOM   24771 O O   . GLU H 1 338 ? -1.568  -55.289 70.791  1.00 27.98  ? 338 GLU H O   1 
ATOM   24772 C CB  . GLU H 1 338 ? -4.726  -54.505 71.682  1.00 32.62  ? 338 GLU H CB  1 
ATOM   24773 C CG  . GLU H 1 338 ? -4.072  -53.187 72.030  1.00 32.67  ? 338 GLU H CG  1 
ATOM   24774 C CD  . GLU H 1 338 ? -5.018  -51.975 71.810  1.00 45.14  ? 338 GLU H CD  1 
ATOM   24775 O OE1 . GLU H 1 338 ? -6.254  -52.130 71.964  1.00 42.09  ? 338 GLU H OE1 1 
ATOM   24776 O OE2 . GLU H 1 338 ? -4.526  -50.867 71.479  1.00 41.53  ? 338 GLU H OE2 1 
ATOM   24777 N N   . ILE H 1 339 ? -3.202  -55.761 69.298  1.00 23.83  ? 339 ILE H N   1 
ATOM   24778 C CA  . ILE H 1 339 ? -2.403  -55.424 68.129  1.00 27.45  ? 339 ILE H CA  1 
ATOM   24779 C C   . ILE H 1 339 ? -3.211  -54.470 67.266  1.00 28.58  ? 339 ILE H C   1 
ATOM   24780 O O   . ILE H 1 339 ? -4.445  -54.448 67.307  1.00 26.31  ? 339 ILE H O   1 
ATOM   24781 C CB  . ILE H 1 339 ? -1.961  -56.657 67.303  1.00 25.70  ? 339 ILE H CB  1 
ATOM   24782 C CG1 . ILE H 1 339 ? -3.171  -57.421 66.789  1.00 21.92  ? 339 ILE H CG1 1 
ATOM   24783 C CG2 . ILE H 1 339 ? -1.020  -57.565 68.098  1.00 20.78  ? 339 ILE H CG2 1 
ATOM   24784 C CD1 . ILE H 1 339 ? -2.835  -58.315 65.662  1.00 27.42  ? 339 ILE H CD1 1 
ATOM   24785 N N   . ASN H 1 340 ? -2.492  -53.680 66.475  1.00 22.97  ? 340 ASN H N   1 
ATOM   24786 C CA  . ASN H 1 340 ? -3.086  -52.741 65.529  1.00 22.43  ? 340 ASN H CA  1 
ATOM   24787 C C   . ASN H 1 340 ? -2.384  -52.912 64.192  1.00 24.53  ? 340 ASN H C   1 
ATOM   24788 O O   . ASN H 1 340 ? -1.221  -52.519 64.047  1.00 23.19  ? 340 ASN H O   1 
ATOM   24789 C CB  . ASN H 1 340 ? -2.947  -51.300 66.024  1.00 24.98  ? 340 ASN H CB  1 
ATOM   24790 C CG  . ASN H 1 340 ? -3.561  -51.101 67.376  1.00 37.21  ? 340 ASN H CG  1 
ATOM   24791 O OD1 . ASN H 1 340 ? -2.867  -50.834 68.363  1.00 45.30  ? 340 ASN H OD1 1 
ATOM   24792 N ND2 . ASN H 1 340 ? -4.873  -51.260 67.446  1.00 31.68  ? 340 ASN H ND2 1 
ATOM   24793 N N   . ALA H 1 341 ? -3.088  -53.477 63.212  1.00 22.91  ? 341 ALA H N   1 
ATOM   24794 C CA  . ALA H 1 341 ? -2.527  -53.682 61.877  1.00 25.10  ? 341 ALA H CA  1 
ATOM   24795 C C   . ALA H 1 341 ? -2.754  -52.400 61.082  1.00 24.19  ? 341 ALA H C   1 
ATOM   24796 O O   . ALA H 1 341 ? -3.749  -52.254 60.375  1.00 27.38  ? 341 ALA H O   1 
ATOM   24797 C CB  . ALA H 1 341 ? -3.144  -54.908 61.213  1.00 20.88  ? 341 ALA H CB  1 
ATOM   24798 N N   . ARG H 1 342 ? -1.803  -51.462 61.214  1.00 19.64  ? 342 ARG H N   1 
ATOM   24799 C CA  . ARG H 1 342 ? -1.821  -50.107 60.655  1.00 23.25  ? 342 ARG H CA  1 
ATOM   24800 C C   . ARG H 1 342 ? -0.720  -49.297 61.325  1.00 22.08  ? 342 ARG H C   1 
ATOM   24801 O O   . ARG H 1 342 ? -0.146  -49.754 62.314  1.00 20.21  ? 342 ARG H O   1 
ATOM   24802 C CB  . ARG H 1 342 ? -3.150  -49.389 60.906  1.00 25.88  ? 342 ARG H CB  1 
ATOM   24803 C CG  . ARG H 1 342 ? -3.639  -49.465 62.359  1.00 24.43  ? 342 ARG H CG  1 
ATOM   24804 C CD  . ARG H 1 342 ? -4.869  -48.593 62.596  1.00 31.06  ? 342 ARG H CD  1 
ATOM   24805 N NE  . ARG H 1 342 ? -4.933  -48.114 63.968  1.00 40.07  ? 342 ARG H NE  1 
ATOM   24806 C CZ  . ARG H 1 342 ? -5.813  -48.548 64.859  1.00 49.83  ? 342 ARG H CZ  1 
ATOM   24807 N NH1 . ARG H 1 342 ? -6.765  -49.404 64.522  1.00 47.34  ? 342 ARG H NH1 1 
ATOM   24808 N NH2 . ARG H 1 342 ? -5.725  -48.129 66.124  1.00 51.27  ? 342 ARG H NH2 1 
ATOM   24809 N N   . TRP H 1 343 ? -0.452  -48.076 60.858  1.00 25.46  ? 343 TRP H N   1 
ATOM   24810 C CA  . TRP H 1 343 ? 0.556   -47.266 61.538  1.00 23.51  ? 343 TRP H CA  1 
ATOM   24811 C C   . TRP H 1 343 ? 0.158   -47.031 62.988  1.00 26.41  ? 343 TRP H C   1 
ATOM   24812 O O   . TRP H 1 343 ? -0.978  -46.639 63.279  1.00 23.55  ? 343 TRP H O   1 
ATOM   24813 C CB  . TRP H 1 343 ? 0.740   -45.912 60.864  1.00 24.88  ? 343 TRP H CB  1 
ATOM   24814 C CG  . TRP H 1 343 ? 1.030   -45.945 59.419  1.00 24.88  ? 343 TRP H CG  1 
ATOM   24815 C CD1 . TRP H 1 343 ? 1.623   -46.944 58.724  1.00 21.80  ? 343 TRP H CD1 1 
ATOM   24816 C CD2 . TRP H 1 343 ? 0.759   -44.904 58.488  1.00 22.08  ? 343 TRP H CD2 1 
ATOM   24817 N NE1 . TRP H 1 343 ? 1.719   -46.602 57.397  1.00 24.87  ? 343 TRP H NE1 1 
ATOM   24818 C CE2 . TRP H 1 343 ? 1.196   -45.348 57.226  1.00 24.51  ? 343 TRP H CE2 1 
ATOM   24819 C CE3 . TRP H 1 343 ? 0.191   -43.632 58.600  1.00 25.40  ? 343 TRP H CE3 1 
ATOM   24820 C CZ2 . TRP H 1 343 ? 1.071   -44.576 56.077  1.00 22.07  ? 343 TRP H CZ2 1 
ATOM   24821 C CZ3 . TRP H 1 343 ? 0.064   -42.865 57.452  1.00 30.24  ? 343 TRP H CZ3 1 
ATOM   24822 C CH2 . TRP H 1 343 ? 0.509   -43.341 56.208  1.00 22.58  ? 343 TRP H CH2 1 
ATOM   24823 N N   . SER H 1 344 ? 1.103   -47.249 63.897  1.00 23.87  ? 344 SER H N   1 
ATOM   24824 C CA  . SER H 1 344 ? 0.939   -46.708 65.226  1.00 20.82  ? 344 SER H CA  1 
ATOM   24825 C C   . SER H 1 344 ? 1.038   -45.182 65.172  1.00 28.79  ? 344 SER H C   1 
ATOM   24826 O O   . SER H 1 344 ? 1.467   -44.591 64.173  1.00 23.51  ? 344 SER H O   1 
ATOM   24827 C CB  . SER H 1 344 ? 2.000   -47.265 66.159  1.00 24.04  ? 344 SER H CB  1 
ATOM   24828 O OG  . SER H 1 344 ? 3.221   -46.577 65.932  1.00 25.03  ? 344 SER H OG  1 
ATOM   24829 N N   . GLY H 1 345 ? 0.625   -44.536 66.265  1.00 28.94  ? 345 GLY H N   1 
ATOM   24830 C CA  . GLY H 1 345 ? 0.774   -43.094 66.349  1.00 23.78  ? 345 GLY H CA  1 
ATOM   24831 C C   . GLY H 1 345 ? 2.230   -42.664 66.364  1.00 26.40  ? 345 GLY H C   1 
ATOM   24832 O O   . GLY H 1 345 ? 2.559   -41.551 65.940  1.00 26.69  ? 345 GLY H O   1 
ATOM   24833 N N   . GLY H 1 346 ? 3.117   -43.545 66.831  1.00 25.13  ? 346 GLY H N   1 
ATOM   24834 C CA  . GLY H 1 346 ? 4.534   -43.306 66.949  1.00 20.61  ? 346 GLY H CA  1 
ATOM   24835 C C   . GLY H 1 346 ? 5.388   -43.813 65.805  1.00 26.11  ? 346 GLY H C   1 
ATOM   24836 O O   . GLY H 1 346 ? 6.620   -43.790 65.928  1.00 23.84  ? 346 GLY H O   1 
ATOM   24837 N N   . LEU H 1 347 ? 4.788   -44.289 64.703  1.00 23.66  ? 347 LEU H N   1 
ATOM   24838 C CA  . LEU H 1 347 ? 5.591   -44.664 63.542  1.00 22.53  ? 347 LEU H CA  1 
ATOM   24839 C C   . LEU H 1 347 ? 6.334   -43.455 63.004  1.00 23.35  ? 347 LEU H C   1 
ATOM   24840 O O   . LEU H 1 347 ? 7.545   -43.511 62.771  1.00 19.72  ? 347 LEU H O   1 
ATOM   24841 C CB  . LEU H 1 347 ? 4.726   -45.277 62.440  1.00 20.52  ? 347 LEU H CB  1 
ATOM   24842 C CG  . LEU H 1 347 ? 5.583   -45.714 61.237  1.00 26.25  ? 347 LEU H CG  1 
ATOM   24843 C CD1 . LEU H 1 347 ? 6.584   -46.825 61.629  1.00 18.66  ? 347 LEU H CD1 1 
ATOM   24844 C CD2 . LEU H 1 347 ? 4.759   -46.148 60.038  1.00 18.27  ? 347 LEU H CD2 1 
ATOM   24845 N N   . ILE H 1 348 ? 5.628   -42.330 62.865  1.00 20.48  ? 348 ILE H N   1 
ATOM   24846 C CA  . ILE H 1 348 ? 6.242   -41.115 62.344  1.00 21.85  ? 348 ILE H CA  1 
ATOM   24847 C C   . ILE H 1 348 ? 7.371   -40.632 63.258  1.00 21.74  ? 348 ILE H C   1 
ATOM   24848 O O   . ILE H 1 348 ? 8.420   -40.184 62.781  1.00 20.32  ? 348 ILE H O   1 
ATOM   24849 C CB  . ILE H 1 348 ? 5.162   -40.031 62.131  1.00 26.38  ? 348 ILE H CB  1 
ATOM   24850 C CG1 . ILE H 1 348 ? 5.734   -38.870 61.330  1.00 19.00  ? 348 ILE H CG1 1 
ATOM   24851 C CG2 . ILE H 1 348 ? 4.560   -39.551 63.460  1.00 22.60  ? 348 ILE H CG2 1 
ATOM   24852 C CD1 . ILE H 1 348 ? 5.892   -39.233 59.870  1.00 21.21  ? 348 ILE H CD1 1 
ATOM   24853 N N   . TYR H 1 349 ? 7.176   -40.682 64.580  1.00 20.40  ? 349 TYR H N   1 
ATOM   24854 C CA  . TYR H 1 349 ? 8.272   -40.302 65.463  1.00 18.87  ? 349 TYR H CA  1 
ATOM   24855 C C   . TYR H 1 349 ? 9.496   -41.144 65.150  1.00 23.36  ? 349 TYR H C   1 
ATOM   24856 O O   . TYR H 1 349 ? 10.623  -40.632 65.071  1.00 19.81  ? 349 TYR H O   1 
ATOM   24857 C CB  . TYR H 1 349 ? 7.898   -40.481 66.939  1.00 19.28  ? 349 TYR H CB  1 
ATOM   24858 C CG  . TYR H 1 349 ? 6.623   -39.820 67.424  1.00 26.84  ? 349 TYR H CG  1 
ATOM   24859 C CD1 . TYR H 1 349 ? 6.104   -38.681 66.813  1.00 24.59  ? 349 TYR H CD1 1 
ATOM   24860 C CD2 . TYR H 1 349 ? 5.949   -40.326 68.528  1.00 28.65  ? 349 TYR H CD2 1 
ATOM   24861 C CE1 . TYR H 1 349 ? 4.922   -38.103 67.277  1.00 24.52  ? 349 TYR H CE1 1 
ATOM   24862 C CE2 . TYR H 1 349 ? 4.773   -39.740 68.999  1.00 26.33  ? 349 TYR H CE2 1 
ATOM   24863 C CZ  . TYR H 1 349 ? 4.269   -38.642 68.375  1.00 24.54  ? 349 TYR H CZ  1 
ATOM   24864 O OH  . TYR H 1 349 ? 3.119   -38.071 68.863  1.00 25.28  ? 349 TYR H OH  1 
ATOM   24865 N N   . HIS H 1 350 ? 9.278   -42.445 64.936  1.00 19.82  ? 350 HIS H N   1 
ATOM   24866 C CA  . HIS H 1 350 ? 10.385  -43.329 64.621  1.00 23.75  ? 350 HIS H CA  1 
ATOM   24867 C C   . HIS H 1 350 ? 11.040  -42.950 63.300  1.00 20.54  ? 350 HIS H C   1 
ATOM   24868 O O   . HIS H 1 350 ? 12.271  -42.976 63.193  1.00 21.73  ? 350 HIS H O   1 
ATOM   24869 C CB  . HIS H 1 350 ? 9.917   -44.780 64.583  1.00 19.30  ? 350 HIS H CB  1 
ATOM   24870 C CG  . HIS H 1 350 ? 10.957  -45.716 64.070  1.00 25.41  ? 350 HIS H CG  1 
ATOM   24871 N ND1 . HIS H 1 350 ? 12.105  -46.005 64.776  1.00 21.79  ? 350 HIS H ND1 1 
ATOM   24872 C CD2 . HIS H 1 350 ? 11.040  -46.412 62.912  1.00 25.45  ? 350 HIS H CD2 1 
ATOM   24873 C CE1 . HIS H 1 350 ? 12.846  -46.848 64.079  1.00 23.16  ? 350 HIS H CE1 1 
ATOM   24874 N NE2 . HIS H 1 350 ? 12.222  -47.111 62.945  1.00 22.10  ? 350 HIS H NE2 1 
ATOM   24875 N N   . THR H 1 351 ? 10.248  -42.593 62.278  1.00 18.78  ? 351 THR H N   1 
ATOM   24876 C CA  . THR H 1 351 ? 10.873  -42.322 60.980  1.00 23.65  ? 351 THR H CA  1 
ATOM   24877 C C   . THR H 1 351 ? 11.631  -40.992 60.994  1.00 25.16  ? 351 THR H C   1 
ATOM   24878 O O   . THR H 1 351 ? 12.737  -40.894 60.440  1.00 25.22  ? 351 THR H O   1 
ATOM   24879 C CB  . THR H 1 351 ? 9.849   -42.354 59.835  1.00 26.22  ? 351 THR H CB  1 
ATOM   24880 O OG1 . THR H 1 351 ? 9.421   -41.037 59.519  1.00 29.45  ? 351 THR H OG1 1 
ATOM   24881 C CG2 . THR H 1 351 ? 8.650   -43.188 60.150  1.00 18.73  ? 351 THR H CG2 1 
ATOM   24882 N N   . VAL H 1 352 ? 11.079  -39.971 61.662  1.00 24.55  ? 352 VAL H N   1 
ATOM   24883 C CA  . VAL H 1 352 ? 11.826  -38.729 61.868  1.00 19.27  ? 352 VAL H CA  1 
ATOM   24884 C C   . VAL H 1 352 ? 13.121  -39.008 62.619  1.00 22.86  ? 352 VAL H C   1 
ATOM   24885 O O   . VAL H 1 352 ? 14.186  -38.499 62.257  1.00 25.64  ? 352 VAL H O   1 
ATOM   24886 C CB  . VAL H 1 352 ? 10.964  -37.682 62.600  1.00 19.40  ? 352 VAL H CB  1 
ATOM   24887 C CG1 . VAL H 1 352 ? 11.787  -36.379 62.917  1.00 22.12  ? 352 VAL H CG1 1 
ATOM   24888 C CG2 . VAL H 1 352 ? 9.763   -37.341 61.780  1.00 20.15  ? 352 VAL H CG2 1 
ATOM   24889 N N   . ALA H 1 353 ? 13.062  -39.827 63.666  1.00 19.72  ? 353 ALA H N   1 
ATOM   24890 C CA  . ALA H 1 353 ? 14.283  -40.112 64.414  1.00 22.52  ? 353 ALA H CA  1 
ATOM   24891 C C   . ALA H 1 353 ? 15.338  -40.757 63.517  1.00 26.70  ? 353 ALA H C   1 
ATOM   24892 O O   . ALA H 1 353 ? 16.515  -40.373 63.552  1.00 25.44  ? 353 ALA H O   1 
ATOM   24893 C CB  . ALA H 1 353 ? 13.982  -41.000 65.619  1.00 17.48  ? 353 ALA H CB  1 
ATOM   24894 N N   . GLU H 1 354 ? 14.922  -41.720 62.687  1.00 23.63  ? 354 GLU H N   1 
ATOM   24895 C CA  . GLU H 1 354 ? 15.841  -42.405 61.789  1.00 24.61  ? 354 GLU H CA  1 
ATOM   24896 C C   . GLU H 1 354 ? 16.409  -41.462 60.732  1.00 29.50  ? 354 GLU H C   1 
ATOM   24897 O O   . GLU H 1 354 ? 17.607  -41.521 60.425  1.00 27.15  ? 354 GLU H O   1 
ATOM   24898 C CB  . GLU H 1 354 ? 15.116  -43.574 61.123  1.00 28.20  ? 354 GLU H CB  1 
ATOM   24899 C CG  . GLU H 1 354 ? 15.998  -44.607 60.460  1.00 32.84  ? 354 GLU H CG  1 
ATOM   24900 C CD  . GLU H 1 354 ? 15.336  -45.976 60.406  1.00 36.74  ? 354 GLU H CD  1 
ATOM   24901 O OE1 . GLU H 1 354 ? 14.255  -46.112 59.779  1.00 34.90  ? 354 GLU H OE1 1 
ATOM   24902 O OE2 . GLU H 1 354 ? 15.898  -46.915 61.008  1.00 37.00  ? 354 GLU H OE2 1 
ATOM   24903 N N   . ARG H 1 355 ? 15.559  -40.616 60.134  1.00 26.04  ? 355 ARG H N   1 
ATOM   24904 C CA  . ARG H 1 355 ? 16.023  -39.744 59.055  1.00 22.93  ? 355 ARG H CA  1 
ATOM   24905 C C   . ARG H 1 355 ? 16.911  -38.620 59.566  1.00 24.17  ? 355 ARG H C   1 
ATOM   24906 O O   . ARG H 1 355 ? 17.732  -38.114 58.808  1.00 29.19  ? 355 ARG H O   1 
ATOM   24907 C CB  . ARG H 1 355 ? 14.838  -39.148 58.300  1.00 22.60  ? 355 ARG H CB  1 
ATOM   24908 C CG  . ARG H 1 355 ? 13.951  -40.180 57.589  1.00 25.74  ? 355 ARG H CG  1 
ATOM   24909 C CD  . ARG H 1 355 ? 12.817  -39.494 56.881  1.00 26.41  ? 355 ARG H CD  1 
ATOM   24910 N NE  . ARG H 1 355 ? 13.294  -38.862 55.660  1.00 28.01  ? 355 ARG H NE  1 
ATOM   24911 C CZ  . ARG H 1 355 ? 12.509  -38.290 54.760  1.00 30.59  ? 355 ARG H CZ  1 
ATOM   24912 N NH1 . ARG H 1 355 ? 11.191  -38.252 54.915  1.00 25.26  ? 355 ARG H NH1 1 
ATOM   24913 N NH2 . ARG H 1 355 ? 13.058  -37.753 53.672  1.00 30.97  ? 355 ARG H NH2 1 
ATOM   24914 N N   . LEU H 1 356 ? 16.758  -38.205 60.829  1.00 24.52  ? 356 LEU H N   1 
ATOM   24915 C CA  . LEU H 1 356 ? 17.539  -37.097 61.369  1.00 22.85  ? 356 LEU H CA  1 
ATOM   24916 C C   . LEU H 1 356 ? 18.799  -37.552 62.090  1.00 26.51  ? 356 LEU H C   1 
ATOM   24917 O O   . LEU H 1 356 ? 19.778  -36.802 62.139  1.00 31.38  ? 356 LEU H O   1 
ATOM   24918 C CB  . LEU H 1 356 ? 16.699  -36.266 62.346  1.00 25.05  ? 356 LEU H CB  1 
ATOM   24919 C CG  . LEU H 1 356 ? 15.567  -35.377 61.807  1.00 28.33  ? 356 LEU H CG  1 
ATOM   24920 C CD1 . LEU H 1 356 ? 15.070  -34.459 62.907  1.00 29.59  ? 356 LEU H CD1 1 
ATOM   24921 C CD2 . LEU H 1 356 ? 16.011  -34.541 60.617  1.00 26.06  ? 356 LEU H CD2 1 
ATOM   24922 N N   . LEU H 1 357 ? 18.796  -38.744 62.678  1.00 27.21  ? 357 LEU H N   1 
ATOM   24923 C CA  . LEU H 1 357 ? 19.901  -39.180 63.509  1.00 24.03  ? 357 LEU H CA  1 
ATOM   24924 C C   . LEU H 1 357 ? 20.489  -40.522 63.096  1.00 26.20  ? 357 LEU H C   1 
ATOM   24925 O O   . LEU H 1 357 ? 21.494  -40.934 63.686  1.00 27.43  ? 357 LEU H O   1 
ATOM   24926 C CB  . LEU H 1 357 ? 19.462  -39.266 64.978  1.00 24.35  ? 357 LEU H CB  1 
ATOM   24927 C CG  . LEU H 1 357 ? 18.811  -38.036 65.615  1.00 28.49  ? 357 LEU H CG  1 
ATOM   24928 C CD1 . LEU H 1 357 ? 18.260  -38.389 66.976  1.00 23.86  ? 357 LEU H CD1 1 
ATOM   24929 C CD2 . LEU H 1 357 ? 19.800  -36.889 65.726  1.00 27.19  ? 357 LEU H CD2 1 
ATOM   24930 N N   . GLY H 1 358 ? 19.893  -41.224 62.141  1.00 23.69  ? 358 GLY H N   1 
ATOM   24931 C CA  . GLY H 1 358 ? 20.441  -42.470 61.648  1.00 31.00  ? 358 GLY H CA  1 
ATOM   24932 C C   . GLY H 1 358 ? 19.684  -43.678 62.182  1.00 30.71  ? 358 GLY H C   1 
ATOM   24933 O O   . GLY H 1 358 ? 18.949  -43.608 63.173  1.00 28.56  ? 358 GLY H O   1 
ATOM   24934 N N   . HIS H 1 359 ? 19.898  -44.818 61.512  1.00 31.80  ? 359 HIS H N   1 
ATOM   24935 C CA  . HIS H 1 359 ? 19.109  -46.011 61.809  1.00 32.00  ? 359 HIS H CA  1 
ATOM   24936 C C   . HIS H 1 359 ? 19.299  -46.490 63.244  1.00 29.66  ? 359 HIS H C   1 
ATOM   24937 O O   . HIS H 1 359 ? 18.365  -47.038 63.843  1.00 31.12  ? 359 HIS H O   1 
ATOM   24938 C CB  . HIS H 1 359 ? 19.457  -47.147 60.846  1.00 28.78  ? 359 HIS H CB  1 
ATOM   24939 C CG  . HIS H 1 359 ? 20.894  -47.562 60.900  1.00 34.77  ? 359 HIS H CG  1 
ATOM   24940 N ND1 . HIS H 1 359 ? 21.867  -47.003 60.093  1.00 32.02  ? 359 HIS H ND1 1 
ATOM   24941 C CD2 . HIS H 1 359 ? 21.529  -48.465 61.684  1.00 26.65  ? 359 HIS H CD2 1 
ATOM   24942 C CE1 . HIS H 1 359 ? 23.033  -47.560 60.366  1.00 25.94  ? 359 HIS H CE1 1 
ATOM   24943 N NE2 . HIS H 1 359 ? 22.855  -48.446 61.331  1.00 29.30  ? 359 HIS H NE2 1 
ATOM   24944 N N   . ASP H 1 360 ? 20.485  -46.322 63.820  1.00 26.98  ? 360 ASP H N   1 
ATOM   24945 C CA  . ASP H 1 360 ? 20.704  -46.799 65.182  1.00 27.87  ? 360 ASP H CA  1 
ATOM   24946 C C   . ASP H 1 360 ? 20.578  -45.685 66.218  1.00 26.97  ? 360 ASP H C   1 
ATOM   24947 O O   . ASP H 1 360 ? 21.271  -45.716 67.241  1.00 24.19  ? 360 ASP H O   1 
ATOM   24948 C CB  . ASP H 1 360 ? 22.062  -47.484 65.301  1.00 34.80  ? 360 ASP H CB  1 
ATOM   24949 C CG  . ASP H 1 360 ? 23.185  -46.607 64.836  1.00 34.55  ? 360 ASP H CG  1 
ATOM   24950 O OD1 . ASP H 1 360 ? 22.985  -45.896 63.826  1.00 41.79  ? 360 ASP H OD1 1 
ATOM   24951 O OD2 . ASP H 1 360 ? 24.255  -46.608 65.488  1.00 42.53  ? 360 ASP H OD2 1 
ATOM   24952 N N   . TYR H 1 361 ? 19.678  -44.715 65.982  1.00 26.33  ? 361 TYR H N   1 
ATOM   24953 C CA  . TYR H 1 361 ? 19.493  -43.613 66.921  1.00 24.45  ? 361 TYR H CA  1 
ATOM   24954 C C   . TYR H 1 361 ? 19.208  -44.099 68.341  1.00 24.35  ? 361 TYR H C   1 
ATOM   24955 O O   . TYR H 1 361 ? 19.610  -43.450 69.309  1.00 23.72  ? 361 TYR H O   1 
ATOM   24956 C CB  . TYR H 1 361 ? 18.358  -42.689 66.444  1.00 27.27  ? 361 TYR H CB  1 
ATOM   24957 C CG  . TYR H 1 361 ? 16.979  -43.315 66.534  1.00 24.32  ? 361 TYR H CG  1 
ATOM   24958 C CD1 . TYR H 1 361 ? 16.227  -43.241 67.706  1.00 28.08  ? 361 TYR H CD1 1 
ATOM   24959 C CD2 . TYR H 1 361 ? 16.438  -43.982 65.451  1.00 24.71  ? 361 TYR H CD2 1 
ATOM   24960 C CE1 . TYR H 1 361 ? 14.984  -43.829 67.790  1.00 24.57  ? 361 TYR H CE1 1 
ATOM   24961 C CE2 . TYR H 1 361 ? 15.206  -44.563 65.521  1.00 24.54  ? 361 TYR H CE2 1 
ATOM   24962 C CZ  . TYR H 1 361 ? 14.484  -44.490 66.683  1.00 23.31  ? 361 TYR H CZ  1 
ATOM   24963 O OH  . TYR H 1 361 ? 13.252  -45.078 66.726  1.00 20.04  ? 361 TYR H OH  1 
ATOM   24964 N N   . ALA H 1 362 ? 18.495  -45.230 68.493  1.00 28.53  ? 362 ALA H N   1 
ATOM   24965 C CA  . ALA H 1 362 ? 18.005  -45.623 69.820  1.00 29.73  ? 362 ALA H CA  1 
ATOM   24966 C C   . ALA H 1 362 ? 19.132  -46.056 70.745  1.00 28.27  ? 362 ALA H C   1 
ATOM   24967 O O   . ALA H 1 362 ? 18.954  -46.065 71.968  1.00 29.96  ? 362 ALA H O   1 
ATOM   24968 C CB  . ALA H 1 362 ? 16.960  -46.733 69.708  1.00 26.14  ? 362 ALA H CB  1 
ATOM   24969 N N   . ARG H 1 363 ? 20.290  -46.390 70.185  1.00 29.30  ? 363 ARG H N   1 
ATOM   24970 C CA  . ARG H 1 363 ? 21.454  -46.711 70.997  1.00 27.87  ? 363 ARG H CA  1 
ATOM   24971 C C   . ARG H 1 363 ? 21.864  -45.538 71.866  1.00 34.29  ? 363 ARG H C   1 
ATOM   24972 O O   . ARG H 1 363 ? 22.247  -45.717 73.029  1.00 39.55  ? 363 ARG H O   1 
ATOM   24973 C CB  . ARG H 1 363 ? 22.603  -47.115 70.087  1.00 36.69  ? 363 ARG H CB  1 
ATOM   24974 C CG  . ARG H 1 363 ? 22.974  -48.573 70.183  1.00 43.50  ? 363 ARG H CG  1 
ATOM   24975 C CD  . ARG H 1 363 ? 24.228  -48.848 69.383  1.00 41.62  ? 363 ARG H CD  1 
ATOM   24976 N NE  . ARG H 1 363 ? 24.138  -50.152 68.748  1.00 40.78  ? 363 ARG H NE  1 
ATOM   24977 C CZ  . ARG H 1 363 ? 24.531  -51.277 69.323  1.00 41.36  ? 363 ARG H CZ  1 
ATOM   24978 N NH1 . ARG H 1 363 ? 25.092  -51.277 70.521  1.00 42.80  ? 363 ARG H NH1 1 
ATOM   24979 N NH2 . ARG H 1 363 ? 24.354  -52.429 68.682  1.00 42.41  ? 363 ARG H NH2 1 
ATOM   24980 N N   . ASN H 1 364 ? 21.786  -44.324 71.323  1.00 33.95  ? 364 ASN H N   1 
ATOM   24981 C CA  . ASN H 1 364 ? 22.321  -43.145 71.985  1.00 32.53  ? 364 ASN H CA  1 
ATOM   24982 C C   . ASN H 1 364 ? 21.279  -42.111 72.368  1.00 35.52  ? 364 ASN H C   1 
ATOM   24983 O O   . ASN H 1 364 ? 21.584  -41.224 73.175  1.00 39.66  ? 364 ASN H O   1 
ATOM   24984 C CB  . ASN H 1 364 ? 23.347  -42.451 71.073  1.00 43.55  ? 364 ASN H CB  1 
ATOM   24985 C CG  . ASN H 1 364 ? 24.755  -42.868 71.367  1.00 42.66  ? 364 ASN H CG  1 
ATOM   24986 O OD1 . ASN H 1 364 ? 24.989  -43.974 71.849  1.00 44.99  ? 364 ASN H OD1 1 
ATOM   24987 N ND2 . ASN H 1 364 ? 25.713  -41.995 71.062  1.00 47.31  ? 364 ASN H ND2 1 
ATOM   24988 N N   . ASN H 1 365 ? 20.086  -42.165 71.803  1.00 28.39  ? 365 ASN H N   1 
ATOM   24989 C CA  . ASN H 1 365 ? 19.242  -40.990 71.819  1.00 27.19  ? 365 ASN H CA  1 
ATOM   24990 C C   . ASN H 1 365 ? 17.911  -41.305 72.456  1.00 27.99  ? 365 ASN H C   1 
ATOM   24991 O O   . ASN H 1 365 ? 17.531  -42.463 72.642  1.00 31.16  ? 365 ASN H O   1 
ATOM   24992 C CB  . ASN H 1 365 ? 19.003  -40.439 70.411  1.00 29.15  ? 365 ASN H CB  1 
ATOM   24993 C CG  . ASN H 1 365 ? 20.275  -40.028 69.719  1.00 31.39  ? 365 ASN H CG  1 
ATOM   24994 O OD1 . ASN H 1 365 ? 20.590  -38.835 69.645  1.00 23.21  ? 365 ASN H OD1 1 
ATOM   24995 N ND2 . ASN H 1 365 ? 21.010  -41.012 69.180  1.00 26.10  ? 365 ASN H ND2 1 
ATOM   24996 N N   . PHE H 1 366 ? 17.201  -40.237 72.770  1.00 26.73  ? 366 PHE H N   1 
ATOM   24997 C CA  . PHE H 1 366 ? 15.854  -40.339 73.283  1.00 25.93  ? 366 PHE H CA  1 
ATOM   24998 C C   . PHE H 1 366 ? 14.966  -39.376 72.520  1.00 25.25  ? 366 PHE H C   1 
ATOM   24999 O O   . PHE H 1 366 ? 15.426  -38.383 71.946  1.00 24.93  ? 366 PHE H O   1 
ATOM   25000 C CB  . PHE H 1 366 ? 15.789  -40.025 74.785  1.00 29.67  ? 366 PHE H CB  1 
ATOM   25001 C CG  . PHE H 1 366 ? 16.637  -40.925 75.636  1.00 32.38  ? 366 PHE H CG  1 
ATOM   25002 C CD1 . PHE H 1 366 ? 16.126  -42.112 76.140  1.00 35.55  ? 366 PHE H CD1 1 
ATOM   25003 C CD2 . PHE H 1 366 ? 17.946  -40.572 75.959  1.00 37.72  ? 366 PHE H CD2 1 
ATOM   25004 C CE1 . PHE H 1 366 ? 16.909  -42.947 76.933  1.00 33.60  ? 366 PHE H CE1 1 
ATOM   25005 C CE2 . PHE H 1 366 ? 18.730  -41.399 76.768  1.00 34.36  ? 366 PHE H CE2 1 
ATOM   25006 C CZ  . PHE H 1 366 ? 18.204  -42.589 77.247  1.00 35.92  ? 366 PHE H CZ  1 
ATOM   25007 N N   . PHE H 1 367 ? 13.674  -39.679 72.512  1.00 22.10  ? 367 PHE H N   1 
ATOM   25008 C CA  . PHE H 1 367 ? 12.735  -38.694 72.033  1.00 28.81  ? 367 PHE H CA  1 
ATOM   25009 C C   . PHE H 1 367 ? 11.443  -38.856 72.805  1.00 29.48  ? 367 PHE H C   1 
ATOM   25010 O O   . PHE H 1 367 ? 11.172  -39.900 73.408  1.00 27.88  ? 367 PHE H O   1 
ATOM   25011 C CB  . PHE H 1 367 ? 12.540  -38.736 70.496  1.00 25.06  ? 367 PHE H CB  1 
ATOM   25012 C CG  . PHE H 1 367 ? 11.895  -39.997 69.937  1.00 24.44  ? 367 PHE H CG  1 
ATOM   25013 C CD1 . PHE H 1 367 ? 10.523  -40.187 70.004  1.00 27.97  ? 367 PHE H CD1 1 
ATOM   25014 C CD2 . PHE H 1 367 ? 12.661  -40.933 69.249  1.00 23.29  ? 367 PHE H CD2 1 
ATOM   25015 C CE1 . PHE H 1 367 ? 9.938   -41.313 69.440  1.00 33.90  ? 367 PHE H CE1 1 
ATOM   25016 C CE2 . PHE H 1 367 ? 12.092  -42.056 68.692  1.00 23.84  ? 367 PHE H CE2 1 
ATOM   25017 C CZ  . PHE H 1 367 ? 10.722  -42.250 68.772  1.00 24.31  ? 367 PHE H CZ  1 
ATOM   25018 N N   . SER H 1 368 ? 10.677  -37.776 72.811  1.00 26.17  ? 368 SER H N   1 
ATOM   25019 C CA  . SER H 1 368 ? 9.426   -37.697 73.536  1.00 25.86  ? 368 SER H CA  1 
ATOM   25020 C C   . SER H 1 368 ? 8.590   -36.673 72.790  1.00 28.72  ? 368 SER H C   1 
ATOM   25021 O O   . SER H 1 368 ? 9.130   -35.680 72.296  1.00 28.46  ? 368 SER H O   1 
ATOM   25022 C CB  . SER H 1 368 ? 9.684   -37.298 74.994  1.00 28.94  ? 368 SER H CB  1 
ATOM   25023 O OG  . SER H 1 368 ? 8.497   -37.001 75.688  1.00 30.27  ? 368 SER H OG  1 
ATOM   25024 N N   . SER H 1 369 ? 7.299   -36.938 72.640  1.00 28.85  ? 369 SER H N   1 
ATOM   25025 C CA  . SER H 1 369 ? 6.439   -36.032 71.895  1.00 26.45  ? 369 SER H CA  1 
ATOM   25026 C C   . SER H 1 369 ? 5.504   -35.306 72.854  1.00 32.13  ? 369 SER H C   1 
ATOM   25027 O O   . SER H 1 369 ? 5.306   -35.728 73.997  1.00 32.61  ? 369 SER H O   1 
ATOM   25028 C CB  . SER H 1 369 ? 5.639   -36.783 70.822  1.00 26.09  ? 369 SER H CB  1 
ATOM   25029 O OG  . SER H 1 369 ? 4.654   -37.623 71.395  1.00 34.33  ? 369 SER H OG  1 
ATOM   25030 N N   . ILE H 1 370 ? 4.948   -34.188 72.384  1.00 29.31  ? 370 ILE H N   1 
ATOM   25031 C CA  . ILE H 1 370 ? 4.023   -33.371 73.159  1.00 27.38  ? 370 ILE H CA  1 
ATOM   25032 C C   . ILE H 1 370 ? 2.863   -33.011 72.244  1.00 32.53  ? 370 ILE H C   1 
ATOM   25033 O O   . ILE H 1 370 ? 3.039   -32.260 71.277  1.00 28.81  ? 370 ILE H O   1 
ATOM   25034 C CB  . ILE H 1 370 ? 4.672   -32.097 73.720  1.00 31.37  ? 370 ILE H CB  1 
ATOM   25035 C CG1 . ILE H 1 370 ? 6.074   -32.364 74.256  1.00 30.70  ? 370 ILE H CG1 1 
ATOM   25036 C CG2 . ILE H 1 370 ? 3.790   -31.485 74.824  1.00 29.77  ? 370 ILE H CG2 1 
ATOM   25037 C CD1 . ILE H 1 370 ? 6.769   -31.098 74.741  1.00 34.48  ? 370 ILE H CD1 1 
ATOM   25038 N N   . LEU H 1 371 ? 1.679   -33.524 72.555  1.00 35.09  ? 371 LEU H N   1 
ATOM   25039 C CA  . LEU H 1 371 ? 0.481   -33.214 71.791  1.00 35.70  ? 371 LEU H CA  1 
ATOM   25040 C C   . LEU H 1 371 ? -0.296  -32.028 72.357  1.00 37.48  ? 371 LEU H C   1 
ATOM   25041 O O   . LEU H 1 371 ? -1.261  -31.581 71.729  1.00 38.60  ? 371 LEU H O   1 
ATOM   25042 C CB  . LEU H 1 371 ? -0.416  -34.461 71.736  1.00 39.36  ? 371 LEU H CB  1 
ATOM   25043 C CG  . LEU H 1 371 ? 0.399   -35.759 71.611  1.00 41.34  ? 371 LEU H CG  1 
ATOM   25044 C CD1 . LEU H 1 371 ? -0.376  -37.001 72.076  1.00 40.50  ? 371 LEU H CD1 1 
ATOM   25045 C CD2 . LEU H 1 371 ? 0.893   -35.934 70.171  1.00 33.21  ? 371 LEU H CD2 1 
ATOM   25046 N N   . ASN H 1 372 ? 0.129   -31.488 73.501  1.00 37.46  ? 372 ASN H N   1 
ATOM   25047 C CA  . ASN H 1 372 ? -0.660  -30.566 74.307  1.00 43.71  ? 372 ASN H CA  1 
ATOM   25048 C C   . ASN H 1 372 ? -0.420  -29.097 73.986  1.00 43.08  ? 372 ASN H C   1 
ATOM   25049 O O   . ASN H 1 372 ? -1.121  -28.244 74.543  1.00 44.04  ? 372 ASN H O   1 
ATOM   25050 C CB  . ASN H 1 372 ? -0.347  -30.778 75.799  1.00 46.24  ? 372 ASN H CB  1 
ATOM   25051 C CG  . ASN H 1 372 ? -1.010  -32.000 76.368  1.00 54.39  ? 372 ASN H CG  1 
ATOM   25052 O OD1 . ASN H 1 372 ? -1.918  -31.895 77.187  1.00 53.33  ? 372 ASN H OD1 1 
ATOM   25053 N ND2 . ASN H 1 372 ? -0.572  -33.179 75.920  1.00 53.85  ? 372 ASN H ND2 1 
ATOM   25054 N N   . VAL H 1 373 ? 0.566   -28.773 73.148  1.00 35.81  ? 373 VAL H N   1 
ATOM   25055 C CA  . VAL H 1 373 ? 1.004   -27.389 73.040  1.00 34.31  ? 373 VAL H CA  1 
ATOM   25056 C C   . VAL H 1 373 ? -0.145  -26.531 72.535  1.00 36.23  ? 373 VAL H C   1 
ATOM   25057 O O   . VAL H 1 373 ? -0.947  -26.961 71.698  1.00 34.62  ? 373 VAL H O   1 
ATOM   25058 C CB  . VAL H 1 373 ? 2.246   -27.289 72.135  1.00 34.85  ? 373 VAL H CB  1 
ATOM   25059 C CG1 . VAL H 1 373 ? 2.498   -25.861 71.697  1.00 35.49  ? 373 VAL H CG1 1 
ATOM   25060 C CG2 . VAL H 1 373 ? 3.478   -27.846 72.856  1.00 33.94  ? 373 VAL H CG2 1 
ATOM   25061 N N   . VAL H 1 374 ? -0.256  -25.324 73.081  1.00 38.73  ? 374 VAL H N   1 
ATOM   25062 C CA  . VAL H 1 374 ? -1.255  -24.362 72.620  1.00 39.27  ? 374 VAL H CA  1 
ATOM   25063 C C   . VAL H 1 374 ? -1.110  -24.216 71.108  1.00 33.85  ? 374 VAL H C   1 
ATOM   25064 O O   . VAL H 1 374 ? 0.006   -24.012 70.612  1.00 36.19  ? 374 VAL H O   1 
ATOM   25065 C CB  . VAL H 1 374 ? -1.098  -23.007 73.340  1.00 37.77  ? 374 VAL H CB  1 
ATOM   25066 C CG1 . VAL H 1 374 ? -2.115  -21.995 72.835  1.00 34.29  ? 374 VAL H CG1 1 
ATOM   25067 C CG2 . VAL H 1 374 ? -1.227  -23.173 74.834  1.00 38.80  ? 374 VAL H CG2 1 
ATOM   25068 N N   . PRO H 1 375 ? -2.190  -24.336 70.341  1.00 30.23  ? 375 PRO H N   1 
ATOM   25069 C CA  . PRO H 1 375 ? -2.080  -24.198 68.888  1.00 35.62  ? 375 PRO H CA  1 
ATOM   25070 C C   . PRO H 1 375 ? -1.622  -22.806 68.493  1.00 36.65  ? 375 PRO H C   1 
ATOM   25071 O O   . PRO H 1 375 ? -1.999  -21.806 69.105  1.00 35.47  ? 375 PRO H O   1 
ATOM   25072 C CB  . PRO H 1 375 ? -3.506  -24.472 68.394  1.00 33.61  ? 375 PRO H CB  1 
ATOM   25073 C CG  . PRO H 1 375 ? -4.146  -25.225 69.481  1.00 35.65  ? 375 PRO H CG  1 
ATOM   25074 C CD  . PRO H 1 375 ? -3.547  -24.715 70.753  1.00 40.10  ? 375 PRO H CD  1 
ATOM   25075 N N   . ALA H 1 376 ? -0.807  -22.752 67.450  1.00 36.45  ? 376 ALA H N   1 
ATOM   25076 C CA  . ALA H 1 376 ? -0.399  -21.485 66.866  1.00 34.64  ? 376 ALA H CA  1 
ATOM   25077 C C   . ALA H 1 376 ? 0.178   -21.802 65.504  1.00 33.62  ? 376 ALA H C   1 
ATOM   25078 O O   . ALA H 1 376 ? 0.577   -22.938 65.241  1.00 31.96  ? 376 ALA H O   1 
ATOM   25079 C CB  . ALA H 1 376 ? 0.617   -20.747 67.744  1.00 27.91  ? 376 ALA H CB  1 
ATOM   25080 N N   . GLY H 1 377 ? 0.188   -20.802 64.632  1.00 31.32  ? 377 GLY H N   1 
ATOM   25081 C CA  . GLY H 1 377 ? 0.772   -20.975 63.322  1.00 32.46  ? 377 GLY H CA  1 
ATOM   25082 C C   . GLY H 1 377 ? 2.203   -21.469 63.419  1.00 30.95  ? 377 GLY H C   1 
ATOM   25083 O O   . GLY H 1 377 ? 2.829   -21.482 64.474  1.00 31.67  ? 377 GLY H O   1 
ATOM   25084 N N   . LEU H 1 378 ? 2.732   -21.886 62.276  1.00 33.14  ? 378 LEU H N   1 
ATOM   25085 C CA  . LEU H 1 378 ? 4.097   -22.395 62.247  1.00 32.47  ? 378 LEU H CA  1 
ATOM   25086 C C   . LEU H 1 378 ? 5.099   -21.346 62.728  1.00 30.35  ? 378 LEU H C   1 
ATOM   25087 O O   . LEU H 1 378 ? 5.992   -21.643 63.535  1.00 27.39  ? 378 LEU H O   1 
ATOM   25088 C CB  . LEU H 1 378 ? 4.436   -22.847 60.834  1.00 32.06  ? 378 LEU H CB  1 
ATOM   25089 C CG  . LEU H 1 378 ? 5.781   -23.552 60.729  1.00 25.55  ? 378 LEU H CG  1 
ATOM   25090 C CD1 . LEU H 1 378 ? 5.781   -24.779 61.647  1.00 19.97  ? 378 LEU H CD1 1 
ATOM   25091 C CD2 . LEU H 1 378 ? 6.070   -23.887 59.265  1.00 25.11  ? 378 LEU H CD2 1 
ATOM   25092 N N   . ALA H 1 379 ? 4.953   -20.108 62.240  1.00 28.98  ? 379 ALA H N   1 
ATOM   25093 C CA  . ALA H 1 379 ? 5.927   -19.054 62.515  1.00 30.74  ? 379 ALA H CA  1 
ATOM   25094 C C   . ALA H 1 379 ? 6.078   -18.814 64.011  1.00 29.93  ? 379 ALA H C   1 
ATOM   25095 O O   . ALA H 1 379 ? 7.197   -18.772 64.538  1.00 28.94  ? 379 ALA H O   1 
ATOM   25096 C CB  . ALA H 1 379 ? 5.512   -17.767 61.798  1.00 31.29  ? 379 ALA H CB  1 
ATOM   25097 N N   . ASP H 1 380 ? 4.952   -18.665 64.711  1.00 27.87  ? 380 ASP H N   1 
ATOM   25098 C CA  . ASP H 1 380 ? 4.974   -18.492 66.156  1.00 25.42  ? 380 ASP H CA  1 
ATOM   25099 C C   . ASP H 1 380 ? 5.521   -19.729 66.873  1.00 29.90  ? 380 ASP H C   1 
ATOM   25100 O O   . ASP H 1 380 ? 6.283   -19.599 67.841  1.00 27.84  ? 380 ASP H O   1 
ATOM   25101 C CB  . ASP H 1 380 ? 3.561   -18.152 66.638  1.00 31.23  ? 380 ASP H CB  1 
ATOM   25102 C CG  . ASP H 1 380 ? 3.070   -16.803 66.111  1.00 38.56  ? 380 ASP H CG  1 
ATOM   25103 O OD1 . ASP H 1 380 ? 3.554   -16.351 65.043  1.00 40.82  ? 380 ASP H OD1 1 
ATOM   25104 O OD2 . ASP H 1 380 ? 2.178   -16.204 66.752  1.00 44.74  ? 380 ASP H OD2 1 
ATOM   25105 N N   . LEU H 1 381 ? 5.137   -20.937 66.431  1.00 24.52  ? 381 LEU H N   1 
ATOM   25106 C CA  . LEU H 1 381 ? 5.633   -22.152 67.079  1.00 26.43  ? 381 LEU H CA  1 
ATOM   25107 C C   . LEU H 1 381 ? 7.152   -22.253 66.982  1.00 23.09  ? 381 LEU H C   1 
ATOM   25108 O O   . LEU H 1 381 ? 7.839   -22.485 67.984  1.00 24.11  ? 381 LEU H O   1 
ATOM   25109 C CB  . LEU H 1 381 ? 4.979   -23.393 66.464  1.00 31.02  ? 381 LEU H CB  1 
ATOM   25110 C CG  . LEU H 1 381 ? 3.928   -24.227 67.216  1.00 32.46  ? 381 LEU H CG  1 
ATOM   25111 C CD1 . LEU H 1 381 ? 3.012   -23.376 68.084  1.00 33.96  ? 381 LEU H CD1 1 
ATOM   25112 C CD2 . LEU H 1 381 ? 3.124   -25.096 66.253  1.00 29.12  ? 381 LEU H CD2 1 
ATOM   25113 N N   . LEU H 1 382 ? 7.695   -22.116 65.774  1.00 20.86  ? 382 LEU H N   1 
ATOM   25114 C CA  . LEU H 1 382 ? 9.146   -22.065 65.616  1.00 19.17  ? 382 LEU H CA  1 
ATOM   25115 C C   . LEU H 1 382 ? 9.759   -20.909 66.411  1.00 22.12  ? 382 LEU H C   1 
ATOM   25116 O O   . LEU H 1 382 ? 10.827  -21.057 67.018  1.00 22.63  ? 382 LEU H O   1 
ATOM   25117 C CB  . LEU H 1 382 ? 9.491   -21.937 64.132  1.00 25.96  ? 382 LEU H CB  1 
ATOM   25118 C CG  . LEU H 1 382 ? 9.140   -23.179 63.294  1.00 26.69  ? 382 LEU H CG  1 
ATOM   25119 C CD1 . LEU H 1 382 ? 9.433   -22.926 61.837  1.00 21.66  ? 382 LEU H CD1 1 
ATOM   25120 C CD2 . LEU H 1 382 ? 9.916   -24.386 63.804  1.00 23.07  ? 382 LEU H CD2 1 
ATOM   25121 N N   . ARG H 1 383 ? 9.091   -19.756 66.451  1.00 23.75  ? 383 ARG H N   1 
ATOM   25122 C CA  . ARG H 1 383 ? 9.646   -18.665 67.247  1.00 26.45  ? 383 ARG H CA  1 
ATOM   25123 C C   . ARG H 1 383 ? 9.702   -19.047 68.720  1.00 25.70  ? 383 ARG H C   1 
ATOM   25124 O O   . ARG H 1 383 ? 10.724  -18.827 69.376  1.00 29.07  ? 383 ARG H O   1 
ATOM   25125 C CB  . ARG H 1 383 ? 8.852   -17.373 67.041  1.00 24.48  ? 383 ARG H CB  1 
ATOM   25126 C CG  . ARG H 1 383 ? 9.463   -16.172 67.781  1.00 28.91  ? 383 ARG H CG  1 
ATOM   25127 C CD  . ARG H 1 383 ? 10.520  -15.423 66.943  1.00 28.56  ? 383 ARG H CD  1 
ATOM   25128 N NE  . ARG H 1 383 ? 11.872  -15.997 66.941  1.00 27.77  ? 383 ARG H NE  1 
ATOM   25129 C CZ  . ARG H 1 383 ? 12.789  -15.842 67.891  1.00 28.93  ? 383 ARG H CZ  1 
ATOM   25130 N NH1 . ARG H 1 383 ? 12.518  -15.221 69.032  1.00 27.63  ? 383 ARG H NH1 1 
ATOM   25131 N NH2 . ARG H 1 383 ? 14.021  -16.314 67.686  1.00 26.88  ? 383 ARG H NH2 1 
ATOM   25132 N N   . SER H 1 384 ? 8.636   -19.674 69.246  1.00 24.59  ? 384 SER H N   1 
ATOM   25133 C CA  . SER H 1 384 ? 8.674   -20.135 70.634  1.00 24.91  ? 384 SER H CA  1 
ATOM   25134 C C   . SER H 1 384 ? 9.755   -21.185 70.845  1.00 25.38  ? 384 SER H C   1 
ATOM   25135 O O   . SER H 1 384 ? 10.368  -21.232 71.916  1.00 28.27  ? 384 SER H O   1 
ATOM   25136 C CB  . SER H 1 384 ? 7.317   -20.701 71.068  1.00 29.91  ? 384 SER H CB  1 
ATOM   25137 O OG  . SER H 1 384 ? 6.262   -19.775 70.855  1.00 27.77  ? 384 SER H OG  1 
ATOM   25138 N N   . LEU H 1 385 ? 9.997   -22.040 69.849  1.00 23.95  ? 385 LEU H N   1 
ATOM   25139 C CA  . LEU H 1 385 ? 11.081  -23.018 69.962  1.00 25.41  ? 385 LEU H CA  1 
ATOM   25140 C C   . LEU H 1 385 ? 12.420  -22.317 70.117  1.00 26.11  ? 385 LEU H C   1 
ATOM   25141 O O   . LEU H 1 385 ? 13.266  -22.723 70.929  1.00 24.33  ? 385 LEU H O   1 
ATOM   25142 C CB  . LEU H 1 385 ? 11.123  -23.919 68.727  1.00 23.89  ? 385 LEU H CB  1 
ATOM   25143 C CG  . LEU H 1 385 ? 10.041  -24.972 68.528  1.00 29.45  ? 385 LEU H CG  1 
ATOM   25144 C CD1 . LEU H 1 385 ? 10.435  -25.880 67.361  1.00 24.83  ? 385 LEU H CD1 1 
ATOM   25145 C CD2 . LEU H 1 385 ? 9.854   -25.774 69.804  1.00 22.89  ? 385 LEU H CD2 1 
ATOM   25146 N N   . GLU H 1 386 ? 12.637  -21.273 69.308  1.00 22.84  ? 386 GLU H N   1 
ATOM   25147 C CA  . GLU H 1 386 ? 13.871  -20.504 69.403  1.00 27.47  ? 386 GLU H CA  1 
ATOM   25148 C C   . GLU H 1 386 ? 13.936  -19.733 70.717  1.00 29.08  ? 386 GLU H C   1 
ATOM   25149 O O   . GLU H 1 386 ? 15.005  -19.632 71.328  1.00 30.84  ? 386 GLU H O   1 
ATOM   25150 C CB  . GLU H 1 386 ? 13.992  -19.562 68.210  1.00 26.96  ? 386 GLU H CB  1 
ATOM   25151 C CG  . GLU H 1 386 ? 14.070  -20.275 66.884  1.00 28.12  ? 386 GLU H CG  1 
ATOM   25152 C CD  . GLU H 1 386 ? 14.430  -19.344 65.741  1.00 29.06  ? 386 GLU H CD  1 
ATOM   25153 O OE1 . GLU H 1 386 ? 15.140  -18.338 65.988  1.00 31.90  ? 386 GLU H OE1 1 
ATOM   25154 O OE2 . GLU H 1 386 ? 13.978  -19.611 64.605  1.00 25.02  ? 386 GLU H OE2 1 
ATOM   25155 N N   . ARG H 1 387 ? 12.801  -19.204 71.184  1.00 30.89  ? 387 ARG H N   1 
ATOM   25156 C CA  . ARG H 1 387 ? 12.825  -18.464 72.441  1.00 31.43  ? 387 ARG H CA  1 
ATOM   25157 C C   . ARG H 1 387 ? 13.205  -19.371 73.605  1.00 32.68  ? 387 ARG H C   1 
ATOM   25158 O O   . ARG H 1 387 ? 13.841  -18.924 74.564  1.00 33.55  ? 387 ARG H O   1 
ATOM   25159 C CB  . ARG H 1 387 ? 11.471  -17.808 72.679  1.00 27.93  ? 387 ARG H CB  1 
ATOM   25160 C CG  . ARG H 1 387 ? 11.441  -16.780 73.808  1.00 33.77  ? 387 ARG H CG  1 
ATOM   25161 C CD  . ARG H 1 387 ? 10.218  -15.870 73.657  1.00 32.57  ? 387 ARG H CD  1 
ATOM   25162 N NE  . ARG H 1 387 ? 8.999   -16.655 73.694  1.00 29.89  ? 387 ARG H NE  1 
ATOM   25163 C CZ  . ARG H 1 387 ? 8.240   -16.927 72.642  1.00 34.18  ? 387 ARG H CZ  1 
ATOM   25164 N NH1 . ARG H 1 387 ? 8.507   -16.427 71.445  1.00 33.70  ? 387 ARG H NH1 1 
ATOM   25165 N NH2 . ARG H 1 387 ? 7.196   -17.732 72.793  1.00 27.69  ? 387 ARG H NH2 1 
ATOM   25166 N N   . ALA H 1 388 ? 12.854  -20.655 73.525  1.00 35.14  ? 388 ALA H N   1 
ATOM   25167 C CA  . ALA H 1 388 ? 13.263  -21.601 74.552  1.00 30.07  ? 388 ALA H CA  1 
ATOM   25168 C C   . ALA H 1 388 ? 14.695  -22.091 74.380  1.00 29.86  ? 388 ALA H C   1 
ATOM   25169 O O   . ALA H 1 388 ? 15.231  -22.706 75.305  1.00 38.47  ? 388 ALA H O   1 
ATOM   25170 C CB  . ALA H 1 388 ? 12.307  -22.797 74.554  1.00 30.14  ? 388 ALA H CB  1 
ATOM   25171 N N   . GLY H 1 389 ? 15.316  -21.867 73.221  1.00 26.34  ? 389 GLY H N   1 
ATOM   25172 C CA  . GLY H 1 389 ? 16.613  -22.472 72.934  1.00 26.61  ? 389 GLY H CA  1 
ATOM   25173 C C   . GLY H 1 389 ? 16.593  -23.968 72.641  1.00 31.52  ? 389 GLY H C   1 
ATOM   25174 O O   . GLY H 1 389 ? 17.522  -24.676 73.039  1.00 35.96  ? 389 GLY H O   1 
ATOM   25175 N N   . VAL H 1 390 ? 15.558  -24.481 71.960  1.00 34.45  ? 390 VAL H N   1 
ATOM   25176 C CA  . VAL H 1 390 ? 15.410  -25.929 71.791  1.00 26.19  ? 390 VAL H CA  1 
ATOM   25177 C C   . VAL H 1 390 ? 14.942  -26.300 70.387  1.00 25.00  ? 390 VAL H C   1 
ATOM   25178 O O   . VAL H 1 390 ? 14.615  -27.460 70.123  1.00 26.46  ? 390 VAL H O   1 
ATOM   25179 C CB  . VAL H 1 390 ? 14.431  -26.510 72.833  1.00 28.69  ? 390 VAL H CB  1 
ATOM   25180 C CG1 . VAL H 1 390 ? 14.929  -26.274 74.231  1.00 25.21  ? 390 VAL H CG1 1 
ATOM   25181 C CG2 . VAL H 1 390 ? 13.045  -25.900 72.645  1.00 27.84  ? 390 VAL H CG2 1 
ATOM   25182 N N   . ARG H 1 391 ? 14.886  -25.338 69.478  1.00 26.08  ? 391 ARG H N   1 
ATOM   25183 C CA  . ARG H 1 391 ? 14.596  -25.673 68.089  1.00 24.72  ? 391 ARG H CA  1 
ATOM   25184 C C   . ARG H 1 391 ? 15.607  -26.679 67.552  1.00 24.91  ? 391 ARG H C   1 
ATOM   25185 O O   . ARG H 1 391 ? 16.819  -26.496 67.710  1.00 26.51  ? 391 ARG H O   1 
ATOM   25186 C CB  . ARG H 1 391 ? 14.613  -24.425 67.210  1.00 24.94  ? 391 ARG H CB  1 
ATOM   25187 C CG  . ARG H 1 391 ? 14.340  -24.791 65.772  1.00 24.36  ? 391 ARG H CG  1 
ATOM   25188 C CD  . ARG H 1 391 ? 13.942  -23.624 64.940  1.00 27.60  ? 391 ARG H CD  1 
ATOM   25189 N NE  . ARG H 1 391 ? 13.810  -24.015 63.543  1.00 24.82  ? 391 ARG H NE  1 
ATOM   25190 C CZ  . ARG H 1 391 ? 13.433  -23.184 62.583  1.00 24.81  ? 391 ARG H CZ  1 
ATOM   25191 N NH1 . ARG H 1 391 ? 13.104  -21.931 62.852  1.00 24.74  ? 391 ARG H NH1 1 
ATOM   25192 N NH2 . ARG H 1 391 ? 13.408  -23.614 61.319  1.00 21.59  ? 391 ARG H NH2 1 
ATOM   25193 N N   . TYR H 1 392 ? 15.109  -27.730 66.899  1.00 22.63  ? 392 TYR H N   1 
ATOM   25194 C CA  . TYR H 1 392 ? 15.995  -28.795 66.452  1.00 26.65  ? 392 TYR H CA  1 
ATOM   25195 C C   . TYR H 1 392 ? 17.182  -28.226 65.687  1.00 27.10  ? 392 TYR H C   1 
ATOM   25196 O O   . TYR H 1 392 ? 17.016  -27.394 64.791  1.00 26.01  ? 392 TYR H O   1 
ATOM   25197 C CB  . TYR H 1 392 ? 15.270  -29.807 65.571  1.00 28.49  ? 392 TYR H CB  1 
ATOM   25198 C CG  . TYR H 1 392 ? 16.230  -30.910 65.173  1.00 28.04  ? 392 TYR H CG  1 
ATOM   25199 C CD1 . TYR H 1 392 ? 16.560  -31.926 66.068  1.00 23.52  ? 392 TYR H CD1 1 
ATOM   25200 C CD2 . TYR H 1 392 ? 16.858  -30.896 63.935  1.00 28.15  ? 392 TYR H CD2 1 
ATOM   25201 C CE1 . TYR H 1 392 ? 17.479  -32.906 65.726  1.00 29.37  ? 392 TYR H CE1 1 
ATOM   25202 C CE2 . TYR H 1 392 ? 17.766  -31.882 63.584  1.00 29.07  ? 392 TYR H CE2 1 
ATOM   25203 C CZ  . TYR H 1 392 ? 18.073  -32.874 64.489  1.00 26.68  ? 392 TYR H CZ  1 
ATOM   25204 O OH  . TYR H 1 392 ? 18.964  -33.843 64.129  1.00 33.95  ? 392 TYR H OH  1 
ATOM   25205 N N   . ASP H 1 393 ? 18.375  -28.704 66.044  1.00 28.84  ? 393 ASP H N   1 
ATOM   25206 C CA  . ASP H 1 393 ? 19.652  -28.164 65.588  1.00 35.62  ? 393 ASP H CA  1 
ATOM   25207 C C   . ASP H 1 393 ? 20.411  -29.263 64.854  1.00 27.42  ? 393 ASP H C   1 
ATOM   25208 O O   . ASP H 1 393 ? 20.818  -30.253 65.463  1.00 29.20  ? 393 ASP H O   1 
ATOM   25209 C CB  . ASP H 1 393 ? 20.468  -27.632 66.779  1.00 31.28  ? 393 ASP H CB  1 
ATOM   25210 C CG  . ASP H 1 393 ? 21.822  -27.043 66.369  1.00 38.40  ? 393 ASP H CG  1 
ATOM   25211 O OD1 . ASP H 1 393 ? 22.295  -27.304 65.243  1.00 42.07  ? 393 ASP H OD1 1 
ATOM   25212 O OD2 . ASP H 1 393 ? 22.415  -26.285 67.173  1.00 37.22  ? 393 ASP H OD2 1 
ATOM   25213 N N   . LYS H 1 394 ? 20.619  -29.065 63.559  1.00 34.23  ? 394 LYS H N   1 
ATOM   25214 C CA  . LYS H 1 394 ? 21.437  -29.928 62.712  1.00 38.47  ? 394 LYS H CA  1 
ATOM   25215 C C   . LYS H 1 394 ? 22.726  -30.408 63.384  1.00 35.38  ? 394 LYS H C   1 
ATOM   25216 O O   . LYS H 1 394 ? 23.107  -31.572 63.229  1.00 31.99  ? 394 LYS H O   1 
ATOM   25217 C CB  . LYS H 1 394 ? 21.781  -29.167 61.430  1.00 44.57  ? 394 LYS H CB  1 
ATOM   25218 C CG  . LYS H 1 394 ? 21.881  -29.994 60.174  1.00 49.79  ? 394 LYS H CG  1 
ATOM   25219 C CD  . LYS H 1 394 ? 21.446  -29.182 58.950  1.00 54.87  ? 394 LYS H CD  1 
ATOM   25220 C CE  . LYS H 1 394 ? 21.974  -27.743 58.977  1.00 52.47  ? 394 LYS H CE  1 
ATOM   25221 N NZ  . LYS H 1 394 ? 23.406  -27.630 58.535  1.00 55.31  ? 394 LYS H NZ  1 
ATOM   25222 N N   . ASP H 1 395 ? 23.412  -29.540 64.135  1.00 33.20  ? 395 ASP H N   1 
ATOM   25223 C CA  . ASP H 1 395 ? 24.778  -29.859 64.547  1.00 36.09  ? 395 ASP H CA  1 
ATOM   25224 C C   . ASP H 1 395 ? 24.856  -30.633 65.849  1.00 36.35  ? 395 ASP H C   1 
ATOM   25225 O O   . ASP H 1 395 ? 25.867  -31.306 66.091  1.00 30.63  ? 395 ASP H O   1 
ATOM   25226 C CB  . ASP H 1 395 ? 25.611  -28.582 64.660  1.00 33.47  ? 395 ASP H CB  1 
ATOM   25227 C CG  . ASP H 1 395 ? 25.593  -27.771 63.369  1.00 42.43  ? 395 ASP H CG  1 
ATOM   25228 O OD1 . ASP H 1 395 ? 25.667  -28.384 62.267  1.00 38.09  ? 395 ASP H OD1 1 
ATOM   25229 O OD2 . ASP H 1 395 ? 25.472  -26.530 63.462  1.00 46.33  ? 395 ASP H OD2 1 
ATOM   25230 N N   . SER H 1 396 ? 23.824  -30.562 66.685  1.00 30.34  ? 396 SER H N   1 
ATOM   25231 C CA  . SER H 1 396 ? 23.771  -31.351 67.898  1.00 29.00  ? 396 SER H CA  1 
ATOM   25232 C C   . SER H 1 396 ? 22.816  -32.532 67.799  1.00 35.44  ? 396 SER H C   1 
ATOM   25233 O O   . SER H 1 396 ? 22.872  -33.424 68.654  1.00 32.09  ? 396 SER H O   1 
ATOM   25234 C CB  . SER H 1 396 ? 23.344  -30.465 69.066  1.00 31.31  ? 396 SER H CB  1 
ATOM   25235 O OG  . SER H 1 396 ? 22.100  -29.853 68.746  1.00 32.87  ? 396 SER H OG  1 
ATOM   25236 N N   . GLY H 1 397 ? 21.926  -32.551 66.804  1.00 31.29  ? 397 GLY H N   1 
ATOM   25237 C CA  . GLY H 1 397 ? 20.874  -33.551 66.776  1.00 28.89  ? 397 GLY H CA  1 
ATOM   25238 C C   . GLY H 1 397 ? 19.937  -33.478 67.961  1.00 31.34  ? 397 GLY H C   1 
ATOM   25239 O O   . GLY H 1 397 ? 19.343  -34.493 68.338  1.00 30.11  ? 397 GLY H O   1 
ATOM   25240 N N   . GLU H 1 398 ? 19.781  -32.297 68.561  1.00 29.84  ? 398 GLU H N   1 
ATOM   25241 C CA  . GLU H 1 398 ? 18.996  -32.139 69.777  1.00 27.28  ? 398 GLU H CA  1 
ATOM   25242 C C   . GLU H 1 398 ? 17.984  -31.016 69.585  1.00 25.53  ? 398 GLU H C   1 
ATOM   25243 O O   . GLU H 1 398 ? 18.247  -30.049 68.867  1.00 22.46  ? 398 GLU H O   1 
ATOM   25244 C CB  . GLU H 1 398 ? 19.902  -31.864 70.991  1.00 28.29  ? 398 GLU H CB  1 
ATOM   25245 C CG  . GLU H 1 398 ? 20.769  -33.072 71.384  1.00 28.75  ? 398 GLU H CG  1 
ATOM   25246 C CD  . GLU H 1 398 ? 21.095  -33.144 72.876  1.00 30.52  ? 398 GLU H CD  1 
ATOM   25247 O OE1 . GLU H 1 398 ? 20.532  -32.346 73.655  1.00 33.98  ? 398 GLU H OE1 1 
ATOM   25248 O OE2 . GLU H 1 398 ? 21.898  -34.023 73.279  1.00 31.51  ? 398 GLU H OE2 1 
ATOM   25249 N N   . GLY H 1 399 ? 16.809  -31.173 70.209  1.00 21.17  ? 399 GLY H N   1 
ATOM   25250 C CA  . GLY H 1 399 ? 15.752  -30.182 70.178  1.00 21.30  ? 399 GLY H CA  1 
ATOM   25251 C C   . GLY H 1 399 ? 14.519  -30.687 69.447  1.00 21.73  ? 399 GLY H C   1 
ATOM   25252 O O   . GLY H 1 399 ? 14.416  -31.853 69.069  1.00 24.77  ? 399 GLY H O   1 
ATOM   25253 N N   . ALA H 1 400 ? 13.585  -29.766 69.220  1.00 25.26  ? 400 ALA H N   1 
ATOM   25254 C CA  . ALA H 1 400 ? 12.221  -30.083 68.815  1.00 24.83  ? 400 ALA H CA  1 
ATOM   25255 C C   . ALA H 1 400 ? 11.948  -29.772 67.345  1.00 21.45  ? 400 ALA H C   1 
ATOM   25256 O O   . ALA H 1 400 ? 12.470  -28.808 66.789  1.00 24.26  ? 400 ALA H O   1 
ATOM   25257 C CB  . ALA H 1 400 ? 11.222  -29.301 69.672  1.00 25.90  ? 400 ALA H CB  1 
ATOM   25258 N N   . VAL H 1 401 ? 11.091  -30.591 66.735  1.00 20.10  ? 401 VAL H N   1 
ATOM   25259 C CA  . VAL H 1 401 ? 10.476  -30.305 65.446  1.00 25.69  ? 401 VAL H CA  1 
ATOM   25260 C C   . VAL H 1 401 ? 8.958   -30.317 65.627  1.00 28.06  ? 401 VAL H C   1 
ATOM   25261 O O   . VAL H 1 401 ? 8.424   -30.890 66.583  1.00 23.37  ? 401 VAL H O   1 
ATOM   25262 C CB  . VAL H 1 401 ? 10.900  -31.300 64.337  1.00 24.01  ? 401 VAL H CB  1 
ATOM   25263 C CG1 . VAL H 1 401 ? 12.407  -31.214 64.068  1.00 21.10  ? 401 VAL H CG1 1 
ATOM   25264 C CG2 . VAL H 1 401 ? 10.539  -32.713 64.717  1.00 24.92  ? 401 VAL H CG2 1 
ATOM   25265 N N   . VAL H 1 402 ? 8.266   -29.676 64.676  1.00 21.87  ? 402 VAL H N   1 
ATOM   25266 C CA  . VAL H 1 402 ? 6.820   -29.497 64.698  1.00 23.02  ? 402 VAL H CA  1 
ATOM   25267 C C   . VAL H 1 402 ? 6.174   -30.541 63.796  1.00 25.56  ? 402 VAL H C   1 
ATOM   25268 O O   . VAL H 1 402 ? 6.562   -30.687 62.630  1.00 26.75  ? 402 VAL H O   1 
ATOM   25269 C CB  . VAL H 1 402 ? 6.435   -28.080 64.231  1.00 18.91  ? 402 VAL H CB  1 
ATOM   25270 C CG1 . VAL H 1 402 ? 4.919   -27.889 64.247  1.00 23.52  ? 402 VAL H CG1 1 
ATOM   25271 C CG2 . VAL H 1 402 ? 7.135   -27.029 65.076  1.00 18.37  ? 402 VAL H CG2 1 
ATOM   25272 N N   . LEU H 1 403 ? 5.155   -31.232 64.311  1.00 21.72  ? 403 LEU H N   1 
ATOM   25273 C CA  . LEU H 1 403 ? 4.408   -32.198 63.515  1.00 20.56  ? 403 LEU H CA  1 
ATOM   25274 C C   . LEU H 1 403 ? 3.001   -31.746 63.173  1.00 26.40  ? 403 LEU H C   1 
ATOM   25275 O O   . LEU H 1 403 ? 2.413   -32.280 62.231  1.00 27.20  ? 403 LEU H O   1 
ATOM   25276 C CB  . LEU H 1 403 ? 4.307   -33.538 64.251  1.00 24.79  ? 403 LEU H CB  1 
ATOM   25277 C CG  . LEU H 1 403 ? 5.557   -34.403 64.398  1.00 31.21  ? 403 LEU H CG  1 
ATOM   25278 C CD1 . LEU H 1 403 ? 5.172   -35.765 64.955  1.00 30.40  ? 403 LEU H CD1 1 
ATOM   25279 C CD2 . LEU H 1 403 ? 6.193   -34.574 63.087  1.00 26.45  ? 403 LEU H CD2 1 
ATOM   25280 N N   . GLY H 1 404 ? 2.443   -30.819 63.945  1.00 26.46  ? 404 GLY H N   1 
ATOM   25281 C CA  . GLY H 1 404 ? 1.155   -30.208 63.705  1.00 28.90  ? 404 GLY H CA  1 
ATOM   25282 C C   . GLY H 1 404 ? 1.092   -28.883 64.450  1.00 28.57  ? 404 GLY H C   1 
ATOM   25283 O O   . GLY H 1 404 ? 1.563   -28.788 65.586  1.00 30.65  ? 404 GLY H O   1 
ATOM   25284 N N   . CYS H 1 405 ? 0.568   -27.850 63.794  1.00 25.26  ? 405 CYS H N   1 
ATOM   25285 C CA  . CYS H 1 405 ? 0.289   -26.571 64.427  1.00 34.03  ? 405 CYS H CA  1 
ATOM   25286 C C   . CYS H 1 405 ? -1.062  -26.548 65.118  1.00 35.91  ? 405 CYS H C   1 
ATOM   25287 O O   . CYS H 1 405 ? -1.251  -25.762 66.053  1.00 35.40  ? 405 CYS H O   1 
ATOM   25288 C CB  . CYS H 1 405 ? 0.308   -25.451 63.389  1.00 34.87  ? 405 CYS H CB  1 
ATOM   25289 S SG  . CYS H 1 405 ? 1.781   -25.433 62.379  1.00 34.04  ? 405 CYS H SG  1 
ATOM   25290 N N   . ASN H 1 406 ? -2.003  -27.381 64.673  1.00 33.99  ? 406 ASN H N   1 
ATOM   25291 C CA  . ASN H 1 406 ? -3.358  -27.344 65.210  1.00 37.21  ? 406 ASN H CA  1 
ATOM   25292 C C   . ASN H 1 406 ? -4.017  -28.703 65.021  1.00 36.35  ? 406 ASN H C   1 
ATOM   25293 O O   . ASN H 1 406 ? -4.847  -28.873 64.127  1.00 32.62  ? 406 ASN H O   1 
ATOM   25294 C CB  . ASN H 1 406 ? -4.166  -26.234 64.522  1.00 34.72  ? 406 ASN H CB  1 
ATOM   25295 C CG  . ASN H 1 406 ? -5.554  -26.055 65.121  1.00 39.78  ? 406 ASN H CG  1 
ATOM   25296 O OD1 . ASN H 1 406 ? -5.806  -26.430 66.265  1.00 39.76  ? 406 ASN H OD1 1 
ATOM   25297 N ND2 . ASN H 1 406 ? -6.457  -25.458 64.350  1.00 40.15  ? 406 ASN H ND2 1 
ATOM   25298 N N   . SER H 1 407 ? -3.643  -29.679 65.845  1.00 36.30  ? 407 SER H N   1 
ATOM   25299 C CA  . SER H 1 407 ? -4.018  -31.069 65.629  1.00 39.08  ? 407 SER H CA  1 
ATOM   25300 C C   . SER H 1 407 ? -5.081  -31.531 66.620  1.00 39.89  ? 407 SER H C   1 
ATOM   25301 O O   . SER H 1 407 ? -5.240  -30.979 67.714  1.00 35.07  ? 407 SER H O   1 
ATOM   25302 C CB  . SER H 1 407 ? -2.799  -31.993 65.738  1.00 32.47  ? 407 SER H CB  1 
ATOM   25303 O OG  . SER H 1 407 ? -3.174  -33.360 65.643  1.00 37.93  ? 407 SER H OG  1 
ATOM   25304 N N   . ASP H 1 408 ? -5.788  -32.584 66.215  1.00 38.05  ? 408 ASP H N   1 
ATOM   25305 C CA  . ASP H 1 408 ? -6.776  -33.258 67.036  1.00 35.40  ? 408 ASP H CA  1 
ATOM   25306 C C   . ASP H 1 408 ? -6.178  -34.332 67.926  1.00 41.43  ? 408 ASP H C   1 
ATOM   25307 O O   . ASP H 1 408 ? -6.899  -34.850 68.778  1.00 42.45  ? 408 ASP H O   1 
ATOM   25308 C CB  . ASP H 1 408 ? -7.852  -33.892 66.153  1.00 40.50  ? 408 ASP H CB  1 
ATOM   25309 C CG  . ASP H 1 408 ? -8.990  -32.941 65.839  1.00 43.84  ? 408 ASP H CG  1 
ATOM   25310 O OD1 . ASP H 1 408 ? -8.949  -31.785 66.303  1.00 44.51  ? 408 ASP H OD1 1 
ATOM   25311 O OD2 . ASP H 1 408 ? -9.935  -33.356 65.134  1.00 52.77  ? 408 ASP H OD2 1 
ATOM   25312 N N   . LEU H 1 409 ? -4.909  -34.707 67.731  1.00 36.56  ? 409 LEU H N   1 
ATOM   25313 C CA  . LEU H 1 409 ? -4.281  -35.712 68.593  1.00 41.56  ? 409 LEU H CA  1 
ATOM   25314 C C   . LEU H 1 409 ? -4.223  -35.179 70.018  1.00 41.51  ? 409 LEU H C   1 
ATOM   25315 O O   . LEU H 1 409 ? -3.782  -34.050 70.236  1.00 46.50  ? 409 LEU H O   1 
ATOM   25316 C CB  . LEU H 1 409 ? -2.866  -36.039 68.104  1.00 36.22  ? 409 LEU H CB  1 
ATOM   25317 C CG  . LEU H 1 409 ? -2.656  -37.127 67.049  1.00 37.36  ? 409 LEU H CG  1 
ATOM   25318 C CD1 . LEU H 1 409 ? -1.208  -37.603 67.108  1.00 32.83  ? 409 LEU H CD1 1 
ATOM   25319 C CD2 . LEU H 1 409 ? -3.636  -38.298 67.188  1.00 32.46  ? 409 LEU H CD2 1 
ATOM   25320 N N   . GLY H 1 410 ? -4.632  -35.993 70.994  1.00 42.44  ? 410 GLY H N   1 
ATOM   25321 C CA  . GLY H 1 410 ? -5.129  -35.427 72.232  1.00 54.68  ? 410 GLY H CA  1 
ATOM   25322 C C   . GLY H 1 410 ? -6.151  -34.397 71.781  1.00 62.57  ? 410 GLY H C   1 
ATOM   25323 O O   . GLY H 1 410 ? -7.174  -34.773 71.201  1.00 64.63  ? 410 GLY H O   1 
ATOM   25324 N N   . PRO H 1 411 ? -5.964  -33.088 72.105  1.00 50.38  ? 411 PRO H N   1 
ATOM   25325 C CA  . PRO H 1 411 ? -5.946  -32.063 71.039  1.00 46.68  ? 411 PRO H CA  1 
ATOM   25326 C C   . PRO H 1 411 ? -4.717  -31.170 71.197  1.00 46.75  ? 411 PRO H C   1 
ATOM   25327 O O   . PRO H 1 411 ? -4.115  -31.187 72.277  1.00 45.82  ? 411 PRO H O   1 
ATOM   25328 C CB  . PRO H 1 411 ? -7.230  -31.255 71.256  1.00 42.03  ? 411 PRO H CB  1 
ATOM   25329 C CG  . PRO H 1 411 ? -8.023  -31.961 72.277  1.00 49.09  ? 411 PRO H CG  1 
ATOM   25330 C CD  . PRO H 1 411 ? -7.087  -32.888 73.034  1.00 54.64  ? 411 PRO H CD  1 
ATOM   25331 N N   . GLY H 1 412 ? -4.320  -30.394 70.163  1.00 41.70  ? 412 GLY H N   1 
ATOM   25332 C CA  . GLY H 1 412 ? -3.337  -29.332 70.304  1.00 38.22  ? 412 GLY H CA  1 
ATOM   25333 C C   . GLY H 1 412 ? -2.273  -29.341 69.205  1.00 37.80  ? 412 GLY H C   1 
ATOM   25334 O O   . GLY H 1 412 ? -2.409  -29.990 68.168  1.00 33.96  ? 412 GLY H O   1 
ATOM   25335 N N   . ALA H 1 413 ? -1.207  -28.566 69.417  1.00 29.51  ? 413 ALA H N   1 
ATOM   25336 C CA  . ALA H 1 413 ? -0.043  -28.654 68.543  1.00 32.51  ? 413 ALA H CA  1 
ATOM   25337 C C   . ALA H 1 413 ? 0.863   -29.782 69.004  1.00 32.25  ? 413 ALA H C   1 
ATOM   25338 O O   . ALA H 1 413 ? 1.026   -30.028 70.206  1.00 29.34  ? 413 ALA H O   1 
ATOM   25339 C CB  . ALA H 1 413 ? 0.752   -27.353 68.522  1.00 33.15  ? 413 ALA H CB  1 
ATOM   25340 N N   . GLU H 1 414 ? 1.462   -30.465 68.031  1.00 27.62  ? 414 GLU H N   1 
ATOM   25341 C CA  . GLU H 1 414 ? 2.303   -31.628 68.290  1.00 26.04  ? 414 GLU H CA  1 
ATOM   25342 C C   . GLU H 1 414 ? 3.755   -31.308 67.908  1.00 24.05  ? 414 GLU H C   1 
ATOM   25343 O O   . GLU H 1 414 ? 4.069   -31.023 66.743  1.00 22.78  ? 414 GLU H O   1 
ATOM   25344 C CB  . GLU H 1 414 ? 1.749   -32.847 67.540  1.00 25.18  ? 414 GLU H CB  1 
ATOM   25345 C CG  . GLU H 1 414 ? 2.694   -34.023 67.466  1.00 22.78  ? 414 GLU H CG  1 
ATOM   25346 C CD  . GLU H 1 414 ? 2.130   -35.194 66.661  1.00 25.75  ? 414 GLU H CD  1 
ATOM   25347 O OE1 . GLU H 1 414 ? 1.490   -34.979 65.602  1.00 25.19  ? 414 GLU H OE1 1 
ATOM   25348 O OE2 . GLU H 1 414 ? 2.339   -36.339 67.104  1.00 25.09  ? 414 GLU H OE2 1 
ATOM   25349 N N   . LEU H 1 415 ? 4.626   -31.336 68.899  1.00 22.87  ? 415 LEU H N   1 
ATOM   25350 C CA  . LEU H 1 415 ? 6.064   -31.260 68.723  1.00 27.65  ? 415 LEU H CA  1 
ATOM   25351 C C   . LEU H 1 415 ? 6.683   -32.596 69.095  1.00 26.48  ? 415 LEU H C   1 
ATOM   25352 O O   . LEU H 1 415 ? 6.149   -33.333 69.929  1.00 25.00  ? 415 LEU H O   1 
ATOM   25353 C CB  . LEU H 1 415 ? 6.692   -30.188 69.611  1.00 31.24  ? 415 LEU H CB  1 
ATOM   25354 C CG  . LEU H 1 415 ? 6.061   -28.806 69.702  1.00 29.93  ? 415 LEU H CG  1 
ATOM   25355 C CD1 . LEU H 1 415 ? 6.557   -28.110 70.968  1.00 30.43  ? 415 LEU H CD1 1 
ATOM   25356 C CD2 . LEU H 1 415 ? 6.435   -28.023 68.462  1.00 28.00  ? 415 LEU H CD2 1 
ATOM   25357 N N   . LEU H 1 416 ? 7.840   -32.872 68.506  1.00 22.53  ? 416 LEU H N   1 
ATOM   25358 C CA  . LEU H 1 416 ? 8.642   -34.047 68.824  1.00 21.72  ? 416 LEU H CA  1 
ATOM   25359 C C   . LEU H 1 416 ? 10.022  -33.573 69.248  1.00 21.55  ? 416 LEU H C   1 
ATOM   25360 O O   . LEU H 1 416 ? 10.650  -32.779 68.540  1.00 24.08  ? 416 LEU H O   1 
ATOM   25361 C CB  . LEU H 1 416 ? 8.733   -34.972 67.608  1.00 21.11  ? 416 LEU H CB  1 
ATOM   25362 C CG  . LEU H 1 416 ? 9.604   -36.228 67.696  1.00 25.98  ? 416 LEU H CG  1 
ATOM   25363 C CD1 . LEU H 1 416 ? 8.949   -37.275 68.595  1.00 29.04  ? 416 LEU H CD1 1 
ATOM   25364 C CD2 . LEU H 1 416 ? 9.825   -36.790 66.281  1.00 25.39  ? 416 LEU H CD2 1 
ATOM   25365 N N   . VAL H 1 417 ? 10.507  -34.057 70.382  1.00 23.89  ? 417 VAL H N   1 
ATOM   25366 C CA  . VAL H 1 417 ? 11.700  -33.493 71.011  1.00 24.97  ? 417 VAL H CA  1 
ATOM   25367 C C   . VAL H 1 417 ? 12.741  -34.588 71.205  1.00 29.25  ? 417 VAL H C   1 
ATOM   25368 O O   . VAL H 1 417 ? 12.436  -35.656 71.754  1.00 28.54  ? 417 VAL H O   1 
ATOM   25369 C CB  . VAL H 1 417 ? 11.370  -32.807 72.351  1.00 22.35  ? 417 VAL H CB  1 
ATOM   25370 C CG1 . VAL H 1 417 ? 12.560  -32.021 72.843  1.00 25.09  ? 417 VAL H CG1 1 
ATOM   25371 C CG2 . VAL H 1 417 ? 10.170  -31.874 72.198  1.00 22.27  ? 417 VAL H CG2 1 
ATOM   25372 N N   . PHE H 1 418 ? 13.974  -34.302 70.771  1.00 22.99  ? 418 PHE H N   1 
ATOM   25373 C CA  . PHE H 1 418 ? 15.096  -35.225 70.790  1.00 19.76  ? 418 PHE H CA  1 
ATOM   25374 C C   . PHE H 1 418 ? 16.173  -34.749 71.750  1.00 24.54  ? 418 PHE H C   1 
ATOM   25375 O O   . PHE H 1 418 ? 16.337  -33.550 71.996  1.00 28.05  ? 418 PHE H O   1 
ATOM   25376 C CB  . PHE H 1 418 ? 15.737  -35.362 69.413  1.00 18.43  ? 418 PHE H CB  1 
ATOM   25377 C CG  . PHE H 1 418 ? 14.824  -35.901 68.373  1.00 21.76  ? 418 PHE H CG  1 
ATOM   25378 C CD1 . PHE H 1 418 ? 14.691  -37.266 68.205  1.00 24.77  ? 418 PHE H CD1 1 
ATOM   25379 C CD2 . PHE H 1 418 ? 14.114  -35.051 67.536  1.00 22.00  ? 418 PHE H CD2 1 
ATOM   25380 C CE1 . PHE H 1 418 ? 13.850  -37.783 67.237  1.00 21.73  ? 418 PHE H CE1 1 
ATOM   25381 C CE2 . PHE H 1 418 ? 13.272  -35.562 66.564  1.00 21.91  ? 418 PHE H CE2 1 
ATOM   25382 C CZ  . PHE H 1 418 ? 13.158  -36.934 66.410  1.00 24.60  ? 418 PHE H CZ  1 
ATOM   25383 N N   . SER H 1 419 ? 16.952  -35.702 72.245  1.00 29.12  ? 419 SER H N   1 
ATOM   25384 C CA  . SER H 1 419 ? 18.097  -35.389 73.082  1.00 28.02  ? 419 SER H CA  1 
ATOM   25385 C C   . SER H 1 419 ? 18.916  -36.655 73.265  1.00 29.35  ? 419 SER H C   1 
ATOM   25386 O O   . SER H 1 419 ? 18.358  -37.754 73.315  1.00 28.26  ? 419 SER H O   1 
ATOM   25387 C CB  . SER H 1 419 ? 17.642  -34.836 74.441  1.00 28.16  ? 419 SER H CB  1 
ATOM   25388 O OG  . SER H 1 419 ? 18.734  -34.343 75.193  1.00 29.30  ? 419 SER H OG  1 
ATOM   25389 N N   . LYS H 1 420 ? 20.236  -36.495 73.369  1.00 32.14  ? 420 LYS H N   1 
ATOM   25390 C CA  . LYS H 1 420 ? 21.089  -37.618 73.742  1.00 31.40  ? 420 LYS H CA  1 
ATOM   25391 C C   . LYS H 1 420 ? 21.025  -37.932 75.233  1.00 35.69  ? 420 LYS H C   1 
ATOM   25392 O O   . LYS H 1 420 ? 21.591  -38.940 75.673  1.00 35.67  ? 420 LYS H O   1 
ATOM   25393 C CB  . LYS H 1 420 ? 22.536  -37.329 73.341  1.00 35.99  ? 420 LYS H CB  1 
ATOM   25394 C CG  . LYS H 1 420 ? 22.776  -37.360 71.833  1.00 33.73  ? 420 LYS H CG  1 
ATOM   25395 C CD  . LYS H 1 420 ? 24.119  -36.748 71.455  1.00 32.62  ? 420 LYS H CD  1 
ATOM   25396 C CE  . LYS H 1 420 ? 24.484  -37.162 70.027  1.00 48.03  ? 420 LYS H CE  1 
ATOM   25397 N NZ  . LYS H 1 420 ? 23.457  -36.691 69.023  1.00 43.10  ? 420 LYS H NZ  1 
ATOM   25398 N N   . ASP H 1 421 ? 20.358  -37.099 76.022  1.00 32.10  ? 421 ASP H N   1 
ATOM   25399 C CA  . ASP H 1 421 ? 20.323  -37.273 77.463  1.00 36.56  ? 421 ASP H CA  1 
ATOM   25400 C C   . ASP H 1 421 ? 18.889  -37.119 77.937  1.00 33.45  ? 421 ASP H C   1 
ATOM   25401 O O   . ASP H 1 421 ? 18.242  -36.107 77.652  1.00 35.68  ? 421 ASP H O   1 
ATOM   25402 C CB  . ASP H 1 421 ? 21.240  -36.269 78.165  1.00 35.25  ? 421 ASP H CB  1 
ATOM   25403 C CG  . ASP H 1 421 ? 21.214  -36.424 79.660  1.00 42.55  ? 421 ASP H CG  1 
ATOM   25404 O OD1 . ASP H 1 421 ? 21.917  -37.323 80.179  1.00 47.64  ? 421 ASP H OD1 1 
ATOM   25405 O OD2 . ASP H 1 421 ? 20.462  -35.663 80.314  1.00 43.39  ? 421 ASP H OD2 1 
ATOM   25406 N N   . TRP H 1 422 ? 18.395  -38.130 78.654  1.00 39.00  ? 422 TRP H N   1 
ATOM   25407 C CA  . TRP H 1 422 ? 16.977  -38.164 79.001  1.00 38.68  ? 422 TRP H CA  1 
ATOM   25408 C C   . TRP H 1 422 ? 16.588  -37.007 79.920  1.00 40.65  ? 422 TRP H C   1 
ATOM   25409 O O   . TRP H 1 422 ? 15.530  -36.394 79.733  1.00 42.10  ? 422 TRP H O   1 
ATOM   25410 C CB  . TRP H 1 422 ? 16.621  -39.500 79.645  1.00 42.07  ? 422 TRP H CB  1 
ATOM   25411 C CG  . TRP H 1 422 ? 15.269  -39.465 80.239  1.00 43.63  ? 422 TRP H CG  1 
ATOM   25412 C CD1 . TRP H 1 422 ? 14.954  -39.373 81.564  1.00 45.79  ? 422 TRP H CD1 1 
ATOM   25413 C CD2 . TRP H 1 422 ? 14.031  -39.483 79.528  1.00 46.65  ? 422 TRP H CD2 1 
ATOM   25414 N NE1 . TRP H 1 422 ? 13.588  -39.349 81.722  1.00 54.58  ? 422 TRP H NE1 1 
ATOM   25415 C CE2 . TRP H 1 422 ? 13.000  -39.410 80.484  1.00 51.77  ? 422 TRP H CE2 1 
ATOM   25416 C CE3 . TRP H 1 422 ? 13.692  -39.558 78.171  1.00 48.16  ? 422 TRP H CE3 1 
ATOM   25417 C CZ2 . TRP H 1 422 ? 11.648  -39.411 80.126  1.00 55.04  ? 422 TRP H CZ2 1 
ATOM   25418 C CZ3 . TRP H 1 422 ? 12.341  -39.549 77.814  1.00 44.58  ? 422 TRP H CZ3 1 
ATOM   25419 C CH2 . TRP H 1 422 ? 11.343  -39.476 78.788  1.00 47.74  ? 422 TRP H CH2 1 
ATOM   25420 N N   . ASP H 1 423 ? 17.417  -36.689 80.923  1.00 41.19  ? 423 ASP H N   1 
ATOM   25421 C CA  . ASP H 1 423 ? 17.046  -35.596 81.824  1.00 44.02  ? 423 ASP H CA  1 
ATOM   25422 C C   . ASP H 1 423 ? 17.076  -34.250 81.110  1.00 38.43  ? 423 ASP H C   1 
ATOM   25423 O O   . ASP H 1 423 ? 16.249  -33.377 81.404  1.00 37.47  ? 423 ASP H O   1 
ATOM   25424 C CB  . ASP H 1 423 ? 17.953  -35.566 83.057  1.00 43.66  ? 423 ASP H CB  1 
ATOM   25425 C CG  . ASP H 1 423 ? 17.686  -36.725 84.010  1.00 50.85  ? 423 ASP H CG  1 
ATOM   25426 O OD1 . ASP H 1 423 ? 16.498  -37.050 84.251  1.00 54.06  ? 423 ASP H OD1 1 
ATOM   25427 O OD2 . ASP H 1 423 ? 18.665  -37.313 84.520  1.00 55.84  ? 423 ASP H OD2 1 
ATOM   25428 N N   . ARG H 1 424 ? 18.000  -34.072 80.164  1.00 38.30  ? 424 ARG H N   1 
ATOM   25429 C CA  . ARG H 1 424 ? 18.001  -32.866 79.344  1.00 30.93  ? 424 ARG H CA  1 
ATOM   25430 C C   . ARG H 1 424 ? 16.791  -32.808 78.414  1.00 34.76  ? 424 ARG H C   1 
ATOM   25431 O O   . ARG H 1 424 ? 16.280  -31.719 78.139  1.00 37.54  ? 424 ARG H O   1 
ATOM   25432 C CB  . ARG H 1 424 ? 19.309  -32.778 78.563  1.00 34.06  ? 424 ARG H CB  1 
ATOM   25433 C CG  . ARG H 1 424 ? 20.485  -32.440 79.481  1.00 41.76  ? 424 ARG H CG  1 
ATOM   25434 C CD  . ARG H 1 424 ? 21.741  -31.892 78.772  1.00 43.44  ? 424 ARG H CD  1 
ATOM   25435 N NE  . ARG H 1 424 ? 22.319  -32.850 77.841  1.00 37.64  ? 424 ARG H NE  1 
ATOM   25436 C CZ  . ARG H 1 424 ? 22.071  -32.848 76.541  1.00 38.61  ? 424 ARG H CZ  1 
ATOM   25437 N NH1 . ARG H 1 424 ? 21.311  -31.914 75.988  1.00 40.52  ? 424 ARG H NH1 1 
ATOM   25438 N NH2 . ARG H 1 424 ? 22.583  -33.811 75.783  1.00 30.76  ? 424 ARG H NH2 1 
ATOM   25439 N N   . LEU H 1 425 ? 16.321  -33.958 77.917  1.00 36.33  ? 425 LEU H N   1 
ATOM   25440 C CA  . LEU H 1 425 ? 15.067  -33.999 77.164  1.00 30.43  ? 425 LEU H CA  1 
ATOM   25441 C C   . LEU H 1 425 ? 13.905  -33.460 78.004  1.00 35.88  ? 425 LEU H C   1 
ATOM   25442 O O   . LEU H 1 425 ? 13.118  -32.619 77.546  1.00 30.64  ? 425 LEU H O   1 
ATOM   25443 C CB  . LEU H 1 425 ? 14.799  -35.439 76.701  1.00 32.44  ? 425 LEU H CB  1 
ATOM   25444 C CG  . LEU H 1 425 ? 13.488  -35.859 75.996  1.00 34.29  ? 425 LEU H CG  1 
ATOM   25445 C CD1 . LEU H 1 425 ? 13.100  -34.891 74.914  1.00 27.42  ? 425 LEU H CD1 1 
ATOM   25446 C CD2 . LEU H 1 425 ? 13.518  -37.304 75.422  1.00 30.25  ? 425 LEU H CD2 1 
ATOM   25447 N N   . THR H 1 426 ? 13.786  -33.931 79.244  1.00 29.76  ? 426 THR H N   1 
ATOM   25448 C CA  . THR H 1 426 ? 12.723  -33.438 80.115  1.00 36.98  ? 426 THR H CA  1 
ATOM   25449 C C   . THR H 1 426 ? 12.845  -31.931 80.335  1.00 37.59  ? 426 THR H C   1 
ATOM   25450 O O   . THR H 1 426 ? 11.861  -31.194 80.207  1.00 33.08  ? 426 THR H O   1 
ATOM   25451 C CB  . THR H 1 426 ? 12.740  -34.191 81.451  1.00 34.16  ? 426 THR H CB  1 
ATOM   25452 O OG1 . THR H 1 426 ? 12.868  -35.598 81.211  1.00 38.08  ? 426 THR H OG1 1 
ATOM   25453 C CG2 . THR H 1 426 ? 11.462  -33.934 82.222  1.00 44.85  ? 426 THR H CG2 1 
ATOM   25454 N N   . ALA H 1 427 ? 14.051  -31.451 80.649  1.00 34.11  ? 427 ALA H N   1 
ATOM   25455 C CA  . ALA H 1 427 ? 14.249  -30.012 80.800  1.00 35.68  ? 427 ALA H CA  1 
ATOM   25456 C C   . ALA H 1 427 ? 13.826  -29.245 79.544  1.00 36.54  ? 427 ALA H C   1 
ATOM   25457 O O   . ALA H 1 427 ? 13.212  -28.172 79.642  1.00 35.20  ? 427 ALA H O   1 
ATOM   25458 C CB  . ALA H 1 427 ? 15.711  -29.714 81.152  1.00 37.36  ? 427 ALA H CB  1 
ATOM   25459 N N   . MET H 1 428 ? 14.133  -29.773 78.351  1.00 31.06  ? 428 MET H N   1 
ATOM   25460 C CA  . MET H 1 428 ? 13.680  -29.094 77.139  1.00 32.04  ? 428 MET H CA  1 
ATOM   25461 C C   . MET H 1 428 ? 12.162  -29.047 77.067  1.00 29.92  ? 428 MET H C   1 
ATOM   25462 O O   . MET H 1 428 ? 11.590  -28.053 76.615  1.00 31.56  ? 428 MET H O   1 
ATOM   25463 C CB  . MET H 1 428 ? 14.218  -29.768 75.880  1.00 29.35  ? 428 MET H CB  1 
ATOM   25464 C CG  . MET H 1 428 ? 15.687  -29.558 75.623  1.00 34.52  ? 428 MET H CG  1 
ATOM   25465 S SD  . MET H 1 428 ? 16.238  -30.709 74.356  1.00 41.93  ? 428 MET H SD  1 
ATOM   25466 C CE  . MET H 1 428 ? 17.803  -29.957 73.910  1.00 41.13  ? 428 MET H CE  1 
ATOM   25467 N N   . LYS H 1 429 ? 11.488  -30.123 77.482  1.00 34.02  ? 429 LYS H N   1 
ATOM   25468 C CA  . LYS H 1 429 ? 10.030  -30.135 77.396  1.00 36.35  ? 429 LYS H CA  1 
ATOM   25469 C C   . LYS H 1 429 ? 9.418   -29.083 78.318  1.00 31.73  ? 429 LYS H C   1 
ATOM   25470 O O   . LYS H 1 429 ? 8.555   -28.308 77.893  1.00 34.97  ? 429 LYS H O   1 
ATOM   25471 C CB  . LYS H 1 429 ? 9.491   -31.538 77.703  1.00 34.79  ? 429 LYS H CB  1 
ATOM   25472 C CG  . LYS H 1 429 ? 9.884   -32.601 76.664  1.00 41.51  ? 429 LYS H CG  1 
ATOM   25473 C CD  . LYS H 1 429 ? 9.831   -34.015 77.225  1.00 32.85  ? 429 LYS H CD  1 
ATOM   25474 C CE  . LYS H 1 429 ? 8.400   -34.463 77.435  1.00 40.17  ? 429 LYS H CE  1 
ATOM   25475 N NZ  . LYS H 1 429 ? 8.295   -35.818 78.050  1.00 41.42  ? 429 LYS H NZ  1 
ATOM   25476 N N   . ASP H 1 430 ? 9.873   -29.026 79.574  1.00 30.75  ? 430 ASP H N   1 
ATOM   25477 C CA  . ASP H 1 430 ? 9.409   -27.995 80.508  1.00 40.75  ? 430 ASP H CA  1 
ATOM   25478 C C   . ASP H 1 430 ? 9.541   -26.602 79.908  1.00 35.69  ? 430 ASP H C   1 
ATOM   25479 O O   . ASP H 1 430 ? 8.585   -25.817 79.900  1.00 33.81  ? 430 ASP H O   1 
ATOM   25480 C CB  . ASP H 1 430 ? 10.208  -28.055 81.812  1.00 35.37  ? 430 ASP H CB  1 
ATOM   25481 C CG  . ASP H 1 430 ? 10.093  -29.389 82.498  1.00 40.13  ? 430 ASP H CG  1 
ATOM   25482 O OD1 . ASP H 1 430 ? 8.996   -29.980 82.457  1.00 46.35  ? 430 ASP H OD1 1 
ATOM   25483 O OD2 . ASP H 1 430 ? 11.093  -29.837 83.102  1.00 46.18  ? 430 ASP H OD2 1 
ATOM   25484 N N   . GLU H 1 431 ? 10.739  -26.284 79.404  1.00 34.98  ? 431 GLU H N   1 
ATOM   25485 C CA  . GLU H 1 431 ? 10.991  -24.979 78.807  1.00 38.81  ? 431 GLU H CA  1 
ATOM   25486 C C   . GLU H 1 431 ? 10.038  -24.690 77.657  1.00 33.46  ? 431 GLU H C   1 
ATOM   25487 O O   . GLU H 1 431 ? 9.664   -23.535 77.444  1.00 35.56  ? 431 GLU H O   1 
ATOM   25488 C CB  . GLU H 1 431 ? 12.442  -24.900 78.326  1.00 35.40  ? 431 GLU H CB  1 
ATOM   25489 C CG  . GLU H 1 431 ? 12.937  -23.483 78.125  1.00 48.32  ? 431 GLU H CG  1 
ATOM   25490 C CD  . GLU H 1 431 ? 13.059  -22.728 79.429  1.00 51.22  ? 431 GLU H CD  1 
ATOM   25491 O OE1 . GLU H 1 431 ? 13.404  -23.373 80.448  1.00 50.99  ? 431 GLU H OE1 1 
ATOM   25492 O OE2 . GLU H 1 431 ? 12.816  -21.501 79.425  1.00 52.95  ? 431 GLU H OE2 1 
ATOM   25493 N N   . ILE H 1 432 ? 9.634   -25.725 76.919  1.00 31.13  ? 432 ILE H N   1 
ATOM   25494 C CA  . ILE H 1 432 ? 8.687   -25.555 75.820  1.00 32.96  ? 432 ILE H CA  1 
ATOM   25495 C C   . ILE H 1 432 ? 7.308   -25.188 76.348  1.00 32.61  ? 432 ILE H C   1 
ATOM   25496 O O   . ILE H 1 432 ? 6.690   -24.221 75.890  1.00 34.93  ? 432 ILE H O   1 
ATOM   25497 C CB  . ILE H 1 432 ? 8.635   -26.832 74.965  1.00 31.30  ? 432 ILE H CB  1 
ATOM   25498 C CG1 . ILE H 1 432 ? 9.841   -26.890 74.037  1.00 35.04  ? 432 ILE H CG1 1 
ATOM   25499 C CG2 . ILE H 1 432 ? 7.347   -26.887 74.169  1.00 29.55  ? 432 ILE H CG2 1 
ATOM   25500 C CD1 . ILE H 1 432 ? 10.122  -28.279 73.515  1.00 34.05  ? 432 ILE H CD1 1 
ATOM   25501 N N   . ALA H 1 433 ? 6.791   -25.971 77.301  1.00 34.79  ? 433 ALA H N   1 
ATOM   25502 C CA  . ALA H 1 433 ? 5.491   -25.660 77.892  1.00 34.94  ? 433 ALA H CA  1 
ATOM   25503 C C   . ALA H 1 433 ? 5.511   -24.296 78.563  1.00 39.21  ? 433 ALA H C   1 
ATOM   25504 O O   . ALA H 1 433 ? 4.520   -23.557 78.517  1.00 41.59  ? 433 ALA H O   1 
ATOM   25505 C CB  . ALA H 1 433 ? 5.090   -26.743 78.891  1.00 37.98  ? 433 ALA H CB  1 
ATOM   25506 N N   . THR H 1 434 ? 6.641   -23.933 79.173  1.00 38.16  ? 434 THR H N   1 
ATOM   25507 C CA  . THR H 1 434 ? 6.797   -22.589 79.725  1.00 39.28  ? 434 THR H CA  1 
ATOM   25508 C C   . THR H 1 434 ? 6.719   -21.526 78.623  1.00 43.79  ? 434 THR H C   1 
ATOM   25509 O O   . THR H 1 434 ? 5.953   -20.557 78.725  1.00 42.04  ? 434 THR H O   1 
ATOM   25510 C CB  . THR H 1 434 ? 8.129   -22.505 80.480  1.00 42.63  ? 434 THR H CB  1 
ATOM   25511 O OG1 . THR H 1 434 ? 7.977   -23.049 81.804  1.00 41.55  ? 434 THR H OG1 1 
ATOM   25512 C CG2 . THR H 1 434 ? 8.648   -21.061 80.539  1.00 37.01  ? 434 THR H CG2 1 
ATOM   25513 N N   . THR H 1 435 ? 7.491   -21.706 77.546  1.00 40.26  ? 435 THR H N   1 
ATOM   25514 C CA  . THR H 1 435 ? 7.534   -20.704 76.484  1.00 38.61  ? 435 THR H CA  1 
ATOM   25515 C C   . THR H 1 435 ? 6.328   -20.792 75.560  1.00 35.45  ? 435 THR H C   1 
ATOM   25516 O O   . THR H 1 435 ? 5.798   -19.760 75.139  1.00 36.35  ? 435 THR H O   1 
ATOM   25517 C CB  . THR H 1 435 ? 8.815   -20.862 75.657  1.00 42.33  ? 435 THR H CB  1 
ATOM   25518 O OG1 . THR H 1 435 ? 9.972   -20.752 76.501  1.00 48.15  ? 435 THR H OG1 1 
ATOM   25519 C CG2 . THR H 1 435 ? 8.881   -19.803 74.585  1.00 34.05  ? 435 THR H CG2 1 
ATOM   25520 N N   . ALA H 1 436 ? 5.904   -22.006 75.196  1.00 34.60  ? 436 ALA H N   1 
ATOM   25521 C CA  . ALA H 1 436 ? 4.858   -22.165 74.194  1.00 32.38  ? 436 ALA H CA  1 
ATOM   25522 C C   . ALA H 1 436 ? 3.469   -22.316 74.792  1.00 34.75  ? 436 ALA H C   1 
ATOM   25523 O O   . ALA H 1 436 ? 2.480   -22.079 74.090  1.00 37.08  ? 436 ALA H O   1 
ATOM   25524 C CB  . ALA H 1 436 ? 5.145   -23.376 73.303  1.00 34.52  ? 436 ALA H CB  1 
ATOM   25525 N N   . GLY H 1 437 ? 3.364   -22.692 76.057  1.00 41.47  ? 437 GLY H N   1 
ATOM   25526 C CA  . GLY H 1 437 ? 2.076   -22.959 76.664  1.00 38.91  ? 437 GLY H CA  1 
ATOM   25527 C C   . GLY H 1 437 ? 1.581   -24.363 76.367  1.00 44.91  ? 437 GLY H C   1 
ATOM   25528 O O   . GLY H 1 437 ? 2.044   -25.049 75.458  1.00 43.26  ? 437 GLY H O   1 
ATOM   25529 N N   . THR H 1 438 ? 0.631   -24.804 77.180  1.00 49.07  ? 438 THR H N   1 
ATOM   25530 C CA  . THR H 1 438 ? -0.045  -26.074 76.986  1.00 46.96  ? 438 THR H CA  1 
ATOM   25531 C C   . THR H 1 438 ? -1.536  -25.855 77.176  1.00 47.60  ? 438 THR H C   1 
ATOM   25532 O O   . THR H 1 438 ? -1.981  -24.789 77.607  1.00 53.27  ? 438 THR H O   1 
ATOM   25533 C CB  . THR H 1 438 ? 0.464   -27.161 77.951  1.00 48.08  ? 438 THR H CB  1 
ATOM   25534 O OG1 . THR H 1 438 ? 0.407   -26.680 79.298  1.00 57.43  ? 438 THR H OG1 1 
ATOM   25535 C CG2 . THR H 1 438 ? 1.881   -27.550 77.622  1.00 44.08  ? 438 THR H CG2 1 
ATOM   25536 N N   . LEU H 1 439 ? -2.314  -26.866 76.820  1.00 43.60  ? 439 LEU H N   1 
ATOM   25537 C CA  . LEU H 1 439 ? -3.732  -26.867 77.122  1.00 50.81  ? 439 LEU H CA  1 
ATOM   25538 C C   . LEU H 1 439 ? -3.935  -27.587 78.451  1.00 55.18  ? 439 LEU H C   1 
ATOM   25539 O O   . LEU H 1 439 ? -3.275  -28.594 78.732  1.00 56.91  ? 439 LEU H O   1 
ATOM   25540 C CB  . LEU H 1 439 ? -4.513  -27.523 75.984  1.00 51.24  ? 439 LEU H CB  1 
ATOM   25541 C CG  . LEU H 1 439 ? -4.260  -26.810 74.645  1.00 42.06  ? 439 LEU H CG  1 
ATOM   25542 C CD1 . LEU H 1 439 ? -5.111  -27.376 73.527  1.00 44.88  ? 439 LEU H CD1 1 
ATOM   25543 C CD2 . LEU H 1 439 ? -4.523  -25.315 74.783  1.00 46.02  ? 439 LEU H CD2 1 
ATOM   25544 N N   . SER H 1 440 ? -4.829  -27.045 79.276  1.00 60.92  ? 440 SER H N   1 
ATOM   25545 C CA  . SER H 1 440 ? -4.823  -27.295 80.725  1.00 68.03  ? 440 SER H CA  1 
ATOM   25546 C C   . SER H 1 440 ? -4.785  -28.778 81.118  1.00 72.17  ? 440 SER H C   1 
ATOM   25547 O O   . SER H 1 440 ? -5.815  -29.457 81.156  1.00 73.55  ? 440 SER H O   1 
ATOM   25548 C CB  . SER H 1 440 ? -6.034  -26.605 81.372  1.00 59.30  ? 440 SER H CB  1 
ATOM   25549 O OG  . SER H 1 440 ? -7.209  -27.388 81.268  1.00 62.58  ? 440 SER H OG  1 
HETATM 25550 O O   . HOH I 2 .   ? 3.007   -16.143 -1.510  1.00 30.51  ? 501 HOH A O   1 
HETATM 25551 O O   . HOH I 2 .   ? 1.193   13.533  -1.393  1.00 36.33  ? 502 HOH A O   1 
HETATM 25552 O O   . HOH I 2 .   ? -27.823 6.936   -7.374  1.00 46.59  ? 503 HOH A O   1 
HETATM 25553 O O   . HOH I 2 .   ? -12.778 -5.522  19.852  1.00 32.00  ? 504 HOH A O   1 
HETATM 25554 O O   . HOH I 2 .   ? 0.939   7.335   21.990  1.00 44.53  ? 505 HOH A O   1 
HETATM 25555 O O   . HOH I 2 .   ? 6.491   4.792   21.311  1.00 40.99  ? 506 HOH A O   1 
HETATM 25556 O O   . HOH I 2 .   ? 5.970   -10.749 -0.564  1.00 43.65  ? 507 HOH A O   1 
HETATM 25557 O O   . HOH I 2 .   ? -24.678 -8.883  1.576   1.00 38.92  ? 508 HOH A O   1 
HETATM 25558 O O   . HOH I 2 .   ? -7.184  21.182  9.079   1.00 38.48  ? 509 HOH A O   1 
HETATM 25559 O O   . HOH I 2 .   ? 3.754   -8.932  -7.195  1.00 40.32  ? 510 HOH A O   1 
HETATM 25560 O O   . HOH I 2 .   ? -5.485  -11.578 -22.983 1.00 39.64  ? 511 HOH A O   1 
HETATM 25561 O O   . HOH I 2 .   ? -4.904  10.088  20.579  1.00 57.11  ? 512 HOH A O   1 
HETATM 25562 O O   . HOH I 2 .   ? 10.714  0.669   13.742  1.00 32.83  ? 513 HOH A O   1 
HETATM 25563 O O   . HOH I 2 .   ? -0.386  -9.122  -5.618  1.00 39.87  ? 514 HOH A O   1 
HETATM 25564 O O   . HOH I 2 .   ? 14.006  -12.912 -3.749  1.00 30.87  ? 515 HOH A O   1 
HETATM 25565 O O   . HOH I 2 .   ? -16.764 13.473  1.490   1.00 23.02  ? 516 HOH A O   1 
HETATM 25566 O O   . HOH I 2 .   ? -6.417  19.334  -5.495  1.00 30.92  ? 517 HOH A O   1 
HETATM 25567 O O   . HOH I 2 .   ? -9.605  25.766  -1.345  1.00 38.85  ? 518 HOH A O   1 
HETATM 25568 O O   . HOH I 2 .   ? -17.190 -4.535  -4.722  1.00 28.69  ? 519 HOH A O   1 
HETATM 25569 O O   . HOH I 2 .   ? -14.836 -1.615  17.638  1.00 35.49  ? 520 HOH A O   1 
HETATM 25570 O O   . HOH I 2 .   ? -13.829 -17.657 -3.826  1.00 26.82  ? 521 HOH A O   1 
HETATM 25571 O O   . HOH I 2 .   ? -2.528  -10.770 -4.060  1.00 31.88  ? 522 HOH A O   1 
HETATM 25572 O O   . HOH I 2 .   ? -11.226 24.533  -9.608  1.00 42.04  ? 523 HOH A O   1 
HETATM 25573 O O   . HOH I 2 .   ? 12.827  -16.007 -0.546  1.00 36.09  ? 524 HOH A O   1 
HETATM 25574 O O   . HOH I 2 .   ? 8.773   -10.799 18.477  1.00 32.90  ? 525 HOH A O   1 
HETATM 25575 O O   . HOH I 2 .   ? 1.893   5.351   7.087   1.00 51.58  ? 526 HOH A O   1 
HETATM 25576 O O   . HOH I 2 .   ? -14.339 -24.975 -11.445 1.00 38.93  ? 527 HOH A O   1 
HETATM 25577 O O   . HOH I 2 .   ? -4.716  -21.443 13.133  1.00 28.60  ? 528 HOH A O   1 
HETATM 25578 O O   . HOH I 2 .   ? -4.313  -3.665  28.940  1.00 26.42  ? 529 HOH A O   1 
HETATM 25579 O O   . HOH I 2 .   ? -12.168 -27.335 -7.074  1.00 53.83  ? 530 HOH A O   1 
HETATM 25580 O O   . HOH I 2 .   ? -10.103 24.315  -3.627  1.00 32.85  ? 531 HOH A O   1 
HETATM 25581 O O   . HOH I 2 .   ? -4.008  7.120   1.549   1.00 29.12  ? 532 HOH A O   1 
HETATM 25582 O O   . HOH I 2 .   ? -12.012 12.813  23.650  1.00 50.23  ? 533 HOH A O   1 
HETATM 25583 O O   . HOH I 2 .   ? -16.767 -20.060 -4.573  1.00 32.48  ? 534 HOH A O   1 
HETATM 25584 O O   . HOH I 2 .   ? -8.967  -19.958 14.819  1.00 25.36  ? 535 HOH A O   1 
HETATM 25585 O O   . HOH I 2 .   ? 6.232   -16.198 -22.591 1.00 32.74  ? 536 HOH A O   1 
HETATM 25586 O O   . HOH I 2 .   ? -12.970 -7.821  -13.783 1.00 44.24  ? 537 HOH A O   1 
HETATM 25587 O O   . HOH I 2 .   ? 0.167   -5.656  -1.861  1.00 50.50  ? 538 HOH A O   1 
HETATM 25588 O O   . HOH I 2 .   ? -26.232 2.824   -17.485 1.00 47.86  ? 539 HOH A O   1 
HETATM 25589 O O   . HOH I 2 .   ? -15.122 -21.571 4.330   1.00 26.60  ? 540 HOH A O   1 
HETATM 25590 O O   . HOH I 2 .   ? 10.296  -14.943 9.065   1.00 37.36  ? 541 HOH A O   1 
HETATM 25591 O O   . HOH I 2 .   ? -5.012  -12.813 12.861  1.00 37.36  ? 542 HOH A O   1 
HETATM 25592 O O   . HOH I 2 .   ? -7.465  -24.198 -6.503  1.00 28.04  ? 543 HOH A O   1 
HETATM 25593 O O   . HOH I 2 .   ? -16.113 17.901  10.478  1.00 24.76  ? 544 HOH A O   1 
HETATM 25594 O O   . HOH I 2 .   ? 23.909  -16.769 -23.903 1.00 56.41  ? 545 HOH A O   1 
HETATM 25595 O O   . HOH I 2 .   ? -14.891 -3.399  15.458  1.00 43.56  ? 546 HOH A O   1 
HETATM 25596 O O   . HOH I 2 .   ? 3.595   -21.166 18.543  1.00 24.48  ? 547 HOH A O   1 
HETATM 25597 O O   . HOH I 2 .   ? 15.220  -16.722 1.167   1.00 39.74  ? 548 HOH A O   1 
HETATM 25598 O O   . HOH I 2 .   ? 5.026   -5.451  12.218  1.00 24.41  ? 549 HOH A O   1 
HETATM 25599 O O   . HOH I 2 .   ? -6.318  -9.380  1.933   1.00 22.28  ? 550 HOH A O   1 
HETATM 25600 O O   . HOH I 2 .   ? 8.476   -21.151 -0.054  1.00 26.76  ? 551 HOH A O   1 
HETATM 25601 O O   . HOH I 2 .   ? 0.177   19.992  -2.637  1.00 45.60  ? 552 HOH A O   1 
HETATM 25602 O O   . HOH I 2 .   ? 6.008   -21.013 -20.809 1.00 37.91  ? 553 HOH A O   1 
HETATM 25603 O O   . HOH I 2 .   ? -27.709 0.236   -3.087  1.00 38.17  ? 554 HOH A O   1 
HETATM 25604 O O   . HOH I 2 .   ? -0.082  -9.022  -29.258 1.00 53.18  ? 555 HOH A O   1 
HETATM 25605 O O   . HOH I 2 .   ? 6.846   9.945   2.101   1.00 45.83  ? 556 HOH A O   1 
HETATM 25606 O O   . HOH I 2 .   ? -19.308 -9.207  1.002   1.00 18.08  ? 557 HOH A O   1 
HETATM 25607 O O   . HOH I 2 .   ? 0.224   -9.127  -8.357  1.00 41.15  ? 558 HOH A O   1 
HETATM 25608 O O   . HOH I 2 .   ? 27.013  -13.014 -18.981 1.00 56.18  ? 559 HOH A O   1 
HETATM 25609 O O   . HOH I 2 .   ? -20.353 -7.388  2.296   1.00 30.97  ? 560 HOH A O   1 
HETATM 25610 O O   . HOH I 2 .   ? -23.671 1.289   -14.977 1.00 34.14  ? 561 HOH A O   1 
HETATM 25611 O O   . HOH I 2 .   ? -4.675  -12.252 25.232  1.00 24.97  ? 562 HOH A O   1 
HETATM 25612 O O   . HOH I 2 .   ? 11.540  -3.401  -24.191 1.00 46.00  ? 563 HOH A O   1 
HETATM 25613 O O   . HOH I 2 .   ? -12.378 -20.760 0.848   1.00 25.89  ? 564 HOH A O   1 
HETATM 25614 O O   . HOH I 2 .   ? -11.928 -17.892 15.061  1.00 28.77  ? 565 HOH A O   1 
HETATM 25615 O O   . HOH I 2 .   ? 7.733   -10.837 12.463  1.00 32.25  ? 566 HOH A O   1 
HETATM 25616 O O   . HOH I 2 .   ? 4.011   1.129   9.734   1.00 33.14  ? 567 HOH A O   1 
HETATM 25617 O O   . HOH I 2 .   ? -23.385 3.157   -17.035 1.00 39.64  ? 568 HOH A O   1 
HETATM 25618 O O   . HOH I 2 .   ? -21.715 -6.316  -1.366  1.00 24.77  ? 569 HOH A O   1 
HETATM 25619 O O   . HOH I 2 .   ? -16.482 23.370  1.050   1.00 26.71  ? 570 HOH A O   1 
HETATM 25620 O O   . HOH I 2 .   ? -1.825  8.750   -2.703  1.00 32.93  ? 571 HOH A O   1 
HETATM 25621 O O   . HOH I 2 .   ? 7.595   -21.285 -23.095 1.00 35.89  ? 572 HOH A O   1 
HETATM 25622 O O   . HOH I 2 .   ? -7.309  -9.065  19.132  1.00 22.16  ? 573 HOH A O   1 
HETATM 25623 O O   . HOH I 2 .   ? -30.031 16.074  -0.179  1.00 45.76  ? 574 HOH A O   1 
HETATM 25624 O O   . HOH I 2 .   ? -17.973 -7.432  4.788   1.00 27.36  ? 575 HOH A O   1 
HETATM 25625 O O   . HOH I 2 .   ? -10.319 -21.568 -22.764 1.00 44.26  ? 576 HOH A O   1 
HETATM 25626 O O   . HOH I 2 .   ? 0.662   3.465   -7.030  1.00 41.18  ? 577 HOH A O   1 
HETATM 25627 O O   . HOH I 2 .   ? -11.562 4.459   23.940  1.00 26.85  ? 578 HOH A O   1 
HETATM 25628 O O   . HOH I 2 .   ? -4.486  7.850   3.699   1.00 27.06  ? 579 HOH A O   1 
HETATM 25629 O O   . HOH I 2 .   ? 16.796  -13.985 9.004   1.00 31.30  ? 580 HOH A O   1 
HETATM 25630 O O   . HOH I 2 .   ? -17.041 -22.948 6.648   1.00 32.62  ? 581 HOH A O   1 
HETATM 25631 O O   . HOH I 2 .   ? -16.238 -1.911  -12.197 1.00 37.74  ? 582 HOH A O   1 
HETATM 25632 O O   . HOH I 2 .   ? -9.066  -26.621 0.230   1.00 24.45  ? 583 HOH A O   1 
HETATM 25633 O O   . HOH I 2 .   ? -10.075 -14.137 12.228  1.00 22.65  ? 584 HOH A O   1 
HETATM 25634 O O   . HOH I 2 .   ? -23.206 10.394  6.209   1.00 41.21  ? 585 HOH A O   1 
HETATM 25635 O O   . HOH I 2 .   ? -7.710  21.709  5.835   1.00 37.42  ? 586 HOH A O   1 
HETATM 25636 O O   . HOH I 2 .   ? -1.613  -11.285 8.288   1.00 24.44  ? 587 HOH A O   1 
HETATM 25637 O O   . HOH I 2 .   ? -18.936 -7.389  -2.021  1.00 24.55  ? 588 HOH A O   1 
HETATM 25638 O O   . HOH I 2 .   ? -7.232  -1.243  2.844   1.00 21.43  ? 589 HOH A O   1 
HETATM 25639 O O   . HOH I 2 .   ? 0.784   -17.726 -11.790 1.00 32.58  ? 590 HOH A O   1 
HETATM 25640 O O   . HOH I 2 .   ? 3.359   -14.431 11.724  1.00 26.69  ? 591 HOH A O   1 
HETATM 25641 O O   . HOH I 2 .   ? -24.421 6.803   3.599   1.00 23.87  ? 592 HOH A O   1 
HETATM 25642 O O   . HOH I 2 .   ? -7.028  -6.722  10.810  1.00 28.35  ? 593 HOH A O   1 
HETATM 25643 O O   . HOH I 2 .   ? -1.018  -28.841 -10.526 1.00 32.29  ? 594 HOH A O   1 
HETATM 25644 O O   . HOH I 2 .   ? -18.135 -16.562 1.556   1.00 30.01  ? 595 HOH A O   1 
HETATM 25645 O O   . HOH I 2 .   ? -8.477  20.424  -3.918  1.00 32.97  ? 596 HOH A O   1 
HETATM 25646 O O   . HOH I 2 .   ? 10.435  -11.677 9.374   1.00 35.06  ? 597 HOH A O   1 
HETATM 25647 O O   . HOH I 2 .   ? 19.004  -6.378  -3.702  1.00 43.04  ? 598 HOH A O   1 
HETATM 25648 O O   . HOH I 2 .   ? -14.231 23.065  3.153   1.00 26.74  ? 599 HOH A O   1 
HETATM 25649 O O   . HOH I 2 .   ? -1.708  6.877   25.327  1.00 41.57  ? 600 HOH A O   1 
HETATM 25650 O O   . HOH I 2 .   ? 2.788   -14.429 -14.115 1.00 46.44  ? 601 HOH A O   1 
HETATM 25651 O O   . HOH I 2 .   ? -9.478  4.989   25.369  1.00 31.48  ? 602 HOH A O   1 
HETATM 25652 O O   . HOH I 2 .   ? -14.324 -19.183 0.708   1.00 28.70  ? 603 HOH A O   1 
HETATM 25653 O O   . HOH I 2 .   ? 10.778  13.801  18.852  1.00 52.45  ? 604 HOH A O   1 
HETATM 25654 O O   . HOH I 2 .   ? 3.386   -15.028 -6.352  1.00 34.49  ? 605 HOH A O   1 
HETATM 25655 O O   . HOH I 2 .   ? -25.813 -0.577  -10.483 1.00 36.50  ? 606 HOH A O   1 
HETATM 25656 O O   . HOH I 2 .   ? -6.180  -17.063 20.041  1.00 29.30  ? 607 HOH A O   1 
HETATM 25657 O O   . HOH I 2 .   ? -12.278 -3.988  33.013  1.00 32.37  ? 608 HOH A O   1 
HETATM 25658 O O   . HOH I 2 .   ? -3.408  -20.441 18.359  1.00 29.30  ? 609 HOH A O   1 
HETATM 25659 O O   . HOH I 2 .   ? -16.657 -20.664 -15.453 1.00 42.47  ? 610 HOH A O   1 
HETATM 25660 O O   . HOH I 2 .   ? -19.453 2.944   16.820  1.00 28.52  ? 611 HOH A O   1 
HETATM 25661 O O   . HOH I 2 .   ? -10.311 -22.473 -13.427 1.00 33.34  ? 612 HOH A O   1 
HETATM 25662 O O   . HOH I 2 .   ? -5.383  -1.113  -15.998 1.00 38.96  ? 613 HOH A O   1 
HETATM 25663 O O   . HOH I 2 .   ? -13.199 17.836  12.112  1.00 31.05  ? 614 HOH A O   1 
HETATM 25664 O O   . HOH I 2 .   ? 5.189   -13.732 9.932   1.00 29.45  ? 615 HOH A O   1 
HETATM 25665 O O   . HOH I 2 .   ? -19.397 -21.945 -2.429  1.00 35.99  ? 616 HOH A O   1 
HETATM 25666 O O   . HOH I 2 .   ? -12.914 -1.195  -15.071 1.00 43.47  ? 617 HOH A O   1 
HETATM 25667 O O   . HOH I 2 .   ? 15.297  -18.746 -28.663 1.00 38.84  ? 618 HOH A O   1 
HETATM 25668 O O   . HOH I 2 .   ? -17.712 -3.017  7.434   1.00 41.81  ? 619 HOH A O   1 
HETATM 25669 O O   . HOH I 2 .   ? -9.888  -23.263 14.227  1.00 50.35  ? 620 HOH A O   1 
HETATM 25670 O O   . HOH I 2 .   ? -19.049 -5.141  -12.411 1.00 48.13  ? 621 HOH A O   1 
HETATM 25671 O O   . HOH I 2 .   ? -26.794 -2.465  -3.615  1.00 37.24  ? 622 HOH A O   1 
HETATM 25672 O O   . HOH I 2 .   ? -5.539  -9.387  8.546   1.00 28.05  ? 623 HOH A O   1 
HETATM 25673 O O   . HOH I 2 .   ? -21.089 1.568   10.205  1.00 40.23  ? 624 HOH A O   1 
HETATM 25674 O O   . HOH I 2 .   ? -9.975  -1.371  31.698  1.00 31.04  ? 625 HOH A O   1 
HETATM 25675 O O   . HOH I 2 .   ? -14.144 -25.422 10.222  1.00 36.37  ? 626 HOH A O   1 
HETATM 25676 O O   . HOH I 2 .   ? -20.581 -18.397 14.167  1.00 38.04  ? 627 HOH A O   1 
HETATM 25677 O O   . HOH I 2 .   ? 12.046  -4.562  13.804  1.00 27.07  ? 628 HOH A O   1 
HETATM 25678 O O   . HOH I 2 .   ? 1.120   -31.556 -7.859  1.00 29.32  ? 629 HOH A O   1 
HETATM 25679 O O   . HOH I 2 .   ? -8.515  6.170   -11.445 1.00 40.82  ? 630 HOH A O   1 
HETATM 25680 O O   . HOH I 2 .   ? -6.576  -24.701 10.982  1.00 35.18  ? 631 HOH A O   1 
HETATM 25681 O O   . HOH I 2 .   ? 0.842   -13.621 -16.302 1.00 34.84  ? 632 HOH A O   1 
HETATM 25682 O O   . HOH I 2 .   ? 24.422  -19.913 -10.695 1.00 49.19  ? 633 HOH A O   1 
HETATM 25683 O O   . HOH I 2 .   ? -29.178 14.499  -3.287  1.00 37.39  ? 634 HOH A O   1 
HETATM 25684 O O   . HOH I 2 .   ? -0.292  -4.733  3.320   1.00 43.76  ? 635 HOH A O   1 
HETATM 25685 O O   . HOH I 2 .   ? -10.349 -6.146  16.016  1.00 32.10  ? 636 HOH A O   1 
HETATM 25686 O O   . HOH I 2 .   ? -2.861  -13.276 23.513  1.00 28.71  ? 637 HOH A O   1 
HETATM 25687 O O   . HOH I 2 .   ? -10.496 -10.184 12.388  1.00 50.89  ? 638 HOH A O   1 
HETATM 25688 O O   . HOH I 2 .   ? -1.418  -11.760 29.772  1.00 42.15  ? 639 HOH A O   1 
HETATM 25689 O O   . HOH I 2 .   ? -0.623  -13.009 -23.690 1.00 39.14  ? 640 HOH A O   1 
HETATM 25690 O O   . HOH I 2 .   ? 8.149   -25.396 -14.770 1.00 36.67  ? 641 HOH A O   1 
HETATM 25691 O O   . HOH I 2 .   ? -6.292  -19.385 17.497  1.00 43.35  ? 642 HOH A O   1 
HETATM 25692 O O   . HOH I 2 .   ? -12.161 3.584   -14.666 1.00 41.42  ? 643 HOH A O   1 
HETATM 25693 O O   . HOH I 2 .   ? 21.829  -21.991 -23.844 1.00 53.32  ? 644 HOH A O   1 
HETATM 25694 O O   . HOH I 2 .   ? -17.583 -7.499  -4.552  1.00 24.37  ? 645 HOH A O   1 
HETATM 25695 O O   . HOH I 2 .   ? -20.784 2.243   12.458  1.00 30.53  ? 646 HOH A O   1 
HETATM 25696 O O   . HOH I 2 .   ? -2.784  -21.107 15.488  1.00 28.42  ? 647 HOH A O   1 
HETATM 25697 O O   . HOH I 2 .   ? 12.663  -8.746  -31.511 1.00 42.37  ? 648 HOH A O   1 
HETATM 25698 O O   . HOH I 2 .   ? -7.773  -11.660 15.377  1.00 33.57  ? 649 HOH A O   1 
HETATM 25699 O O   . HOH I 2 .   ? 1.641   -20.429 -18.808 1.00 27.68  ? 650 HOH A O   1 
HETATM 25700 O O   . HOH I 2 .   ? -14.829 -4.121  7.126   1.00 29.16  ? 651 HOH A O   1 
HETATM 25701 O O   . HOH I 2 .   ? 2.307   -14.787 -3.452  1.00 24.36  ? 652 HOH A O   1 
HETATM 25702 O O   . HOH I 2 .   ? -6.235  9.302   -11.895 1.00 39.49  ? 653 HOH A O   1 
HETATM 25703 O O   . HOH I 2 .   ? -14.703 -8.653  7.946   1.00 34.45  ? 654 HOH A O   1 
HETATM 25704 O O   . HOH I 2 .   ? -5.778  -15.362 -24.990 1.00 44.52  ? 655 HOH A O   1 
HETATM 25705 O O   . HOH I 2 .   ? 11.683  -4.533  -1.681  1.00 49.05  ? 656 HOH A O   1 
HETATM 25706 O O   . HOH I 2 .   ? 3.676   -13.668 24.131  1.00 31.38  ? 657 HOH A O   1 
HETATM 25707 O O   . HOH I 2 .   ? -8.979  -29.431 -1.389  1.00 37.15  ? 658 HOH A O   1 
HETATM 25708 O O   . HOH I 2 .   ? -9.438  -10.272 28.637  1.00 48.38  ? 659 HOH A O   1 
HETATM 25709 O O   . HOH I 2 .   ? 4.949   -10.660 5.230   1.00 36.90  ? 660 HOH A O   1 
HETATM 25710 O O   . HOH I 2 .   ? 9.629   -5.459  11.078  1.00 28.46  ? 661 HOH A O   1 
HETATM 25711 O O   . HOH I 2 .   ? 3.782   -8.468  3.752   1.00 40.62  ? 662 HOH A O   1 
HETATM 25712 O O   . HOH I 2 .   ? -15.737 -10.512 8.593   1.00 40.50  ? 663 HOH A O   1 
HETATM 25713 O O   . HOH I 2 .   ? 6.352   -14.352 24.013  1.00 35.67  ? 664 HOH A O   1 
HETATM 25714 O O   . HOH I 2 .   ? -11.915 -12.725 13.561  1.00 28.73  ? 665 HOH A O   1 
HETATM 25715 O O   . HOH I 2 .   ? -19.581 -21.110 9.230   1.00 40.41  ? 666 HOH A O   1 
HETATM 25716 O O   . HOH I 2 .   ? -9.118  -10.616 18.540  1.00 50.95  ? 667 HOH A O   1 
HETATM 25717 O O   . HOH I 2 .   ? -25.481 4.401   7.170   1.00 42.77  ? 668 HOH A O   1 
HETATM 25718 O O   . HOH I 2 .   ? 5.863   17.371  9.340   1.00 57.02  ? 669 HOH A O   1 
HETATM 25719 O O   . HOH I 2 .   ? 7.394   4.827   19.139  1.00 43.12  ? 670 HOH A O   1 
HETATM 25720 O O   . HOH I 2 .   ? -5.221  10.355  22.795  1.00 50.35  ? 671 HOH A O   1 
HETATM 25721 O O   . HOH I 2 .   ? 7.482   11.896  0.420   1.00 39.25  ? 672 HOH A O   1 
HETATM 25722 O O   . HOH I 2 .   ? -23.856 6.248   7.747   1.00 48.49  ? 673 HOH A O   1 
HETATM 25723 O O   . HOH I 2 .   ? -15.488 -7.325  9.860   1.00 43.11  ? 674 HOH A O   1 
HETATM 25724 O O   . HOH I 2 .   ? -10.673 -26.142 -8.796  1.00 39.80  ? 675 HOH A O   1 
HETATM 25725 O O   . HOH I 2 .   ? -7.082  -23.894 15.105  1.00 45.37  ? 676 HOH A O   1 
HETATM 25726 O O   . HOH I 2 .   ? -16.734 -18.667 -0.554  1.00 39.33  ? 677 HOH A O   1 
HETATM 25727 O O   . HOH I 2 .   ? -4.766  -18.273 22.132  1.00 33.88  ? 678 HOH A O   1 
HETATM 25728 O O   . HOH I 2 .   ? -13.522 -25.422 -1.075  1.00 33.61  ? 679 HOH A O   1 
HETATM 25729 O O   . HOH I 2 .   ? -19.653 0.853   18.480  1.00 39.42  ? 680 HOH A O   1 
HETATM 25730 O O   . HOH I 2 .   ? -11.170 -1.835  -16.319 1.00 46.19  ? 681 HOH A O   1 
HETATM 25731 O O   . HOH I 2 .   ? -16.799 -17.706 -3.236  1.00 29.09  ? 682 HOH A O   1 
HETATM 25732 O O   . HOH I 2 .   ? 4.274   -1.205  0.841   1.00 59.41  ? 683 HOH A O   1 
HETATM 25733 O O   . HOH I 2 .   ? -0.779  -2.058  1.854   1.00 35.64  ? 684 HOH A O   1 
HETATM 25734 O O   . HOH I 2 .   ? 13.048  0.532   17.918  1.00 45.45  ? 685 HOH A O   1 
HETATM 25735 O O   . HOH I 2 .   ? 2.712   0.009   1.360   1.00 43.41  ? 686 HOH A O   1 
HETATM 25736 O O   . HOH I 2 .   ? -8.219  -9.469  12.365  1.00 42.83  ? 687 HOH A O   1 
HETATM 25737 O O   . HOH I 2 .   ? 11.688  -6.879  11.184  1.00 35.94  ? 688 HOH A O   1 
HETATM 25738 O O   . HOH I 2 .   ? 8.655   17.080  16.036  1.00 44.20  ? 689 HOH A O   1 
HETATM 25739 O O   . HOH I 2 .   ? 16.127  -6.569  14.705  1.00 45.87  ? 690 HOH A O   1 
HETATM 25740 O O   . HOH J 2 .   ? 17.103  -33.102 9.694   1.00 49.46  ? 501 HOH B O   1 
HETATM 25741 O O   . HOH J 2 .   ? 13.603  -24.901 -7.168  1.00 41.54  ? 502 HOH B O   1 
HETATM 25742 O O   . HOH J 2 .   ? 24.784  -36.064 25.385  1.00 37.97  ? 503 HOH B O   1 
HETATM 25743 O O   . HOH J 2 .   ? 30.521  -44.300 -14.275 1.00 51.55  ? 504 HOH B O   1 
HETATM 25744 O O   . HOH J 2 .   ? 32.617  -58.103 10.511  1.00 36.34  ? 505 HOH B O   1 
HETATM 25745 O O   . HOH J 2 .   ? 7.388   -62.213 0.049   1.00 38.55  ? 506 HOH B O   1 
HETATM 25746 O O   . HOH J 2 .   ? 24.609  -45.177 13.649  1.00 48.55  ? 507 HOH B O   1 
HETATM 25747 O O   . HOH J 2 .   ? 28.658  -45.953 -8.863  1.00 53.33  ? 508 HOH B O   1 
HETATM 25748 O O   . HOH J 2 .   ? -1.599  -37.559 26.241  1.00 40.87  ? 509 HOH B O   1 
HETATM 25749 O O   . HOH J 2 .   ? 37.470  -42.676 2.949   1.00 48.11  ? 510 HOH B O   1 
HETATM 25750 O O   . HOH J 2 .   ? 17.977  -45.564 22.006  1.00 45.21  ? 511 HOH B O   1 
HETATM 25751 O O   . HOH J 2 .   ? 10.629  -29.580 13.141  1.00 33.16  ? 512 HOH B O   1 
HETATM 25752 O O   . HOH J 2 .   ? 5.756   -36.038 -6.086  1.00 39.50  ? 513 HOH B O   1 
HETATM 25753 O O   . HOH J 2 .   ? 14.120  -55.837 25.631  1.00 47.59  ? 514 HOH B O   1 
HETATM 25754 O O   . HOH J 2 .   ? 13.329  -25.591 28.880  1.00 33.23  ? 515 HOH B O   1 
HETATM 25755 O O   . HOH J 2 .   ? 26.000  -45.521 -15.181 1.00 52.38  ? 516 HOH B O   1 
HETATM 25756 O O   . HOH J 2 .   ? 23.823  -50.230 16.640  1.00 42.27  ? 517 HOH B O   1 
HETATM 25757 O O   . HOH J 2 .   ? 11.078  -21.995 29.344  1.00 36.30  ? 518 HOH B O   1 
HETATM 25758 O O   . HOH J 2 .   ? 36.068  -59.822 4.382   1.00 37.64  ? 519 HOH B O   1 
HETATM 25759 O O   . HOH J 2 .   ? 3.080   -29.048 28.291  1.00 55.91  ? 520 HOH B O   1 
HETATM 25760 O O   . HOH J 2 .   ? 22.314  -41.221 25.764  1.00 52.79  ? 521 HOH B O   1 
HETATM 25761 O O   . HOH J 2 .   ? -4.223  -45.330 -4.457  1.00 37.41  ? 522 HOH B O   1 
HETATM 25762 O O   . HOH J 2 .   ? 22.278  -67.039 -1.387  1.00 34.61  ? 523 HOH B O   1 
HETATM 25763 O O   . HOH J 2 .   ? 5.722   -48.705 -26.190 1.00 46.75  ? 524 HOH B O   1 
HETATM 25764 O O   . HOH J 2 .   ? 33.311  -65.417 9.045   1.00 40.65  ? 525 HOH B O   1 
HETATM 25765 O O   . HOH J 2 .   ? 13.999  -25.171 -9.039  1.00 58.90  ? 526 HOH B O   1 
HETATM 25766 O O   . HOH J 2 .   ? -2.289  -32.692 14.130  1.00 27.26  ? 527 HOH B O   1 
HETATM 25767 O O   . HOH J 2 .   ? 24.775  -45.167 21.583  1.00 52.00  ? 528 HOH B O   1 
HETATM 25768 O O   . HOH J 2 .   ? 24.597  -12.118 20.361  1.00 45.22  ? 529 HOH B O   1 
HETATM 25769 O O   . HOH J 2 .   ? 4.517   -26.902 -11.696 1.00 32.01  ? 530 HOH B O   1 
HETATM 25770 O O   . HOH J 2 .   ? 28.960  -69.422 5.224   1.00 26.86  ? 531 HOH B O   1 
HETATM 25771 O O   . HOH J 2 .   ? 9.066   -41.234 5.074   1.00 22.67  ? 532 HOH B O   1 
HETATM 25772 O O   . HOH J 2 .   ? 6.211   -37.273 -15.951 1.00 40.47  ? 533 HOH B O   1 
HETATM 25773 O O   . HOH J 2 .   ? -1.382  -42.190 12.188  1.00 27.97  ? 534 HOH B O   1 
HETATM 25774 O O   . HOH J 2 .   ? 9.457   -22.275 6.641   1.00 26.10  ? 535 HOH B O   1 
HETATM 25775 O O   . HOH J 2 .   ? 25.583  -26.242 7.755   1.00 53.51  ? 536 HOH B O   1 
HETATM 25776 O O   . HOH J 2 .   ? 13.151  -31.276 14.170  1.00 39.40  ? 537 HOH B O   1 
HETATM 25777 O O   . HOH J 2 .   ? -1.742  -37.405 -7.391  1.00 28.35  ? 538 HOH B O   1 
HETATM 25778 O O   . HOH J 2 .   ? -3.474  -48.072 18.497  1.00 40.98  ? 539 HOH B O   1 
HETATM 25779 O O   . HOH J 2 .   ? 19.729  -23.204 9.367   1.00 31.72  ? 540 HOH B O   1 
HETATM 25780 O O   . HOH J 2 .   ? 15.093  -46.600 3.740   1.00 24.70  ? 541 HOH B O   1 
HETATM 25781 O O   . HOH J 2 .   ? 9.680   -59.903 -9.025  1.00 40.32  ? 542 HOH B O   1 
HETATM 25782 O O   . HOH J 2 .   ? 9.042   -10.432 15.607  1.00 27.09  ? 543 HOH B O   1 
HETATM 25783 O O   . HOH J 2 .   ? 7.806   -46.248 20.983  1.00 36.73  ? 544 HOH B O   1 
HETATM 25784 O O   . HOH J 2 .   ? 10.791  -15.708 15.281  1.00 27.20  ? 545 HOH B O   1 
HETATM 25785 O O   . HOH J 2 .   ? 10.728  -24.667 -10.015 1.00 31.06  ? 546 HOH B O   1 
HETATM 25786 O O   . HOH J 2 .   ? 32.401  -61.230 9.641   1.00 36.35  ? 547 HOH B O   1 
HETATM 25787 O O   . HOH J 2 .   ? 34.211  -55.725 18.060  1.00 44.16  ? 548 HOH B O   1 
HETATM 25788 O O   . HOH J 2 .   ? 21.041  -63.235 5.363   1.00 25.03  ? 549 HOH B O   1 
HETATM 25789 O O   . HOH J 2 .   ? 18.098  -50.889 16.903  1.00 40.24  ? 550 HOH B O   1 
HETATM 25790 O O   . HOH J 2 .   ? 28.696  -48.154 18.134  1.00 52.57  ? 551 HOH B O   1 
HETATM 25791 O O   . HOH J 2 .   ? 11.573  -32.207 23.392  1.00 46.37  ? 552 HOH B O   1 
HETATM 25792 O O   . HOH J 2 .   ? -5.990  -41.070 3.669   1.00 38.67  ? 553 HOH B O   1 
HETATM 25793 O O   . HOH J 2 .   ? 7.639   -47.277 -8.635  1.00 29.61  ? 554 HOH B O   1 
HETATM 25794 O O   . HOH J 2 .   ? -6.944  -36.026 -4.111  1.00 34.74  ? 555 HOH B O   1 
HETATM 25795 O O   . HOH J 2 .   ? 31.971  -48.447 6.967   1.00 34.67  ? 556 HOH B O   1 
HETATM 25796 O O   . HOH J 2 .   ? 10.531  -37.063 10.607  1.00 30.08  ? 557 HOH B O   1 
HETATM 25797 O O   . HOH J 2 .   ? 25.888  -46.034 14.839  1.00 46.36  ? 558 HOH B O   1 
HETATM 25798 O O   . HOH J 2 .   ? -3.274  -60.469 7.433   1.00 31.45  ? 559 HOH B O   1 
HETATM 25799 O O   . HOH J 2 .   ? -2.026  -40.743 -7.233  1.00 29.79  ? 560 HOH B O   1 
HETATM 25800 O O   . HOH J 2 .   ? 5.299   -39.267 -18.485 1.00 40.34  ? 561 HOH B O   1 
HETATM 25801 O O   . HOH J 2 .   ? 10.429  -62.984 12.632  1.00 32.88  ? 562 HOH B O   1 
HETATM 25802 O O   . HOH J 2 .   ? 21.401  -57.717 25.890  1.00 55.88  ? 563 HOH B O   1 
HETATM 25803 O O   . HOH J 2 .   ? -5.951  -32.812 8.081   1.00 27.13  ? 564 HOH B O   1 
HETATM 25804 O O   . HOH J 2 .   ? 10.421  -36.654 -1.537  1.00 26.33  ? 565 HOH B O   1 
HETATM 25805 O O   . HOH J 2 .   ? 27.998  -21.038 27.568  1.00 42.36  ? 566 HOH B O   1 
HETATM 25806 O O   . HOH J 2 .   ? 23.833  -32.767 8.743   1.00 50.25  ? 567 HOH B O   1 
HETATM 25807 O O   . HOH J 2 .   ? 15.637  -30.148 8.591   1.00 45.85  ? 568 HOH B O   1 
HETATM 25808 O O   . HOH J 2 .   ? 29.083  -32.096 23.524  1.00 38.79  ? 569 HOH B O   1 
HETATM 25809 O O   . HOH J 2 .   ? 15.060  -27.169 -16.372 1.00 40.83  ? 570 HOH B O   1 
HETATM 25810 O O   . HOH J 2 .   ? 35.123  -65.872 7.187   1.00 32.56  ? 571 HOH B O   1 
HETATM 25811 O O   . HOH J 2 .   ? 21.506  -69.654 -4.678  1.00 50.84  ? 572 HOH B O   1 
HETATM 25812 O O   . HOH J 2 .   ? -0.728  -45.165 -5.716  1.00 36.33  ? 573 HOH B O   1 
HETATM 25813 O O   . HOH J 2 .   ? 11.555  -16.191 22.932  1.00 32.40  ? 574 HOH B O   1 
HETATM 25814 O O   . HOH J 2 .   ? 36.121  -37.981 -4.127  1.00 43.47  ? 575 HOH B O   1 
HETATM 25815 O O   . HOH J 2 .   ? 28.981  -10.553 26.067  1.00 56.06  ? 576 HOH B O   1 
HETATM 25816 O O   . HOH J 2 .   ? 14.650  -33.592 17.957  1.00 41.79  ? 577 HOH B O   1 
HETATM 25817 O O   . HOH J 2 .   ? -5.474  -34.937 1.319   1.00 36.90  ? 578 HOH B O   1 
HETATM 25818 O O   . HOH J 2 .   ? 8.164   -29.961 18.717  1.00 30.24  ? 579 HOH B O   1 
HETATM 25819 O O   . HOH J 2 .   ? 26.886  -39.051 31.754  1.00 57.94  ? 580 HOH B O   1 
HETATM 25820 O O   . HOH J 2 .   ? 19.357  -52.573 -22.217 1.00 44.49  ? 581 HOH B O   1 
HETATM 25821 O O   . HOH J 2 .   ? 20.520  -36.582 -0.780  1.00 49.87  ? 582 HOH B O   1 
HETATM 25822 O O   . HOH J 2 .   ? 0.719   -61.012 3.660   1.00 31.18  ? 583 HOH B O   1 
HETATM 25823 O O   . HOH J 2 .   ? 36.044  -50.733 23.344  1.00 45.94  ? 584 HOH B O   1 
HETATM 25824 O O   . HOH J 2 .   ? 19.719  -51.340 19.781  1.00 41.98  ? 585 HOH B O   1 
HETATM 25825 O O   . HOH J 2 .   ? 15.535  -36.736 10.891  1.00 48.70  ? 586 HOH B O   1 
HETATM 25826 O O   . HOH J 2 .   ? 24.285  -16.677 8.203   1.00 36.78  ? 587 HOH B O   1 
HETATM 25827 O O   . HOH J 2 .   ? 22.120  -69.748 10.791  1.00 30.58  ? 588 HOH B O   1 
HETATM 25828 O O   . HOH J 2 .   ? 14.047  -47.086 1.064   1.00 24.95  ? 589 HOH B O   1 
HETATM 25829 O O   . HOH J 2 .   ? 14.928  -32.212 0.976   1.00 37.30  ? 590 HOH B O   1 
HETATM 25830 O O   . HOH J 2 .   ? 9.223   -17.841 16.270  1.00 25.18  ? 591 HOH B O   1 
HETATM 25831 O O   . HOH J 2 .   ? 6.538   -52.434 12.200  1.00 31.15  ? 592 HOH B O   1 
HETATM 25832 O O   . HOH J 2 .   ? 4.928   -62.259 18.627  1.00 42.54  ? 593 HOH B O   1 
HETATM 25833 O O   . HOH J 2 .   ? 19.875  -29.732 32.474  1.00 39.65  ? 594 HOH B O   1 
HETATM 25834 O O   . HOH J 2 .   ? 2.410   -41.418 -4.784  1.00 29.30  ? 595 HOH B O   1 
HETATM 25835 O O   . HOH J 2 .   ? 16.171  -53.584 -18.774 1.00 44.24  ? 596 HOH B O   1 
HETATM 25836 O O   . HOH J 2 .   ? 18.847  -10.717 22.386  1.00 31.78  ? 597 HOH B O   1 
HETATM 25837 O O   . HOH J 2 .   ? -6.165  -39.513 24.006  1.00 51.51  ? 598 HOH B O   1 
HETATM 25838 O O   . HOH J 2 .   ? 16.715  -40.241 3.279   1.00 38.56  ? 599 HOH B O   1 
HETATM 25839 O O   . HOH J 2 .   ? 11.411  -13.071 19.531  1.00 46.27  ? 600 HOH B O   1 
HETATM 25840 O O   . HOH J 2 .   ? 26.115  -9.921  19.181  1.00 47.78  ? 601 HOH B O   1 
HETATM 25841 O O   . HOH J 2 .   ? 25.745  -63.862 -5.587  1.00 32.07  ? 602 HOH B O   1 
HETATM 25842 O O   . HOH J 2 .   ? 9.055   -51.243 -2.805  1.00 34.30  ? 603 HOH B O   1 
HETATM 25843 O O   . HOH J 2 .   ? 25.346  -37.363 31.053  1.00 55.60  ? 604 HOH B O   1 
HETATM 25844 O O   . HOH J 2 .   ? 23.561  -71.885 11.586  1.00 32.47  ? 605 HOH B O   1 
HETATM 25845 O O   . HOH J 2 .   ? 9.926   -30.467 8.398   1.00 34.98  ? 606 HOH B O   1 
HETATM 25846 O O   . HOH J 2 .   ? -4.015  -45.937 7.043   1.00 32.06  ? 607 HOH B O   1 
HETATM 25847 O O   . HOH J 2 .   ? -6.066  -29.860 15.867  1.00 39.07  ? 608 HOH B O   1 
HETATM 25848 O O   . HOH J 2 .   ? 36.367  -58.106 9.059   1.00 37.10  ? 609 HOH B O   1 
HETATM 25849 O O   . HOH J 2 .   ? 28.481  -35.985 -12.087 1.00 44.22  ? 610 HOH B O   1 
HETATM 25850 O O   . HOH J 2 .   ? -8.016  -39.771 2.047   1.00 41.77  ? 611 HOH B O   1 
HETATM 25851 O O   . HOH J 2 .   ? 9.332   -66.814 6.029   1.00 37.17  ? 612 HOH B O   1 
HETATM 25852 O O   . HOH J 2 .   ? 1.981   -61.977 11.259  1.00 52.90  ? 613 HOH B O   1 
HETATM 25853 O O   . HOH J 2 .   ? 20.465  -39.345 0.566   1.00 41.28  ? 614 HOH B O   1 
HETATM 25854 O O   . HOH J 2 .   ? 4.480   -50.915 12.766  1.00 24.08  ? 615 HOH B O   1 
HETATM 25855 O O   . HOH J 2 .   ? -2.427  -35.794 21.589  1.00 32.59  ? 616 HOH B O   1 
HETATM 25856 O O   . HOH J 2 .   ? -0.468  -33.386 -6.114  1.00 33.93  ? 617 HOH B O   1 
HETATM 25857 O O   . HOH J 2 .   ? -5.439  -45.874 22.421  1.00 43.51  ? 618 HOH B O   1 
HETATM 25858 O O   . HOH J 2 .   ? 1.226   -48.410 -1.021  1.00 30.11  ? 619 HOH B O   1 
HETATM 25859 O O   . HOH J 2 .   ? 24.043  -18.958 34.675  1.00 54.70  ? 620 HOH B O   1 
HETATM 25860 O O   . HOH J 2 .   ? 5.813   -22.592 20.640  1.00 36.95  ? 621 HOH B O   1 
HETATM 25861 O O   . HOH J 2 .   ? 4.059   -59.574 19.099  1.00 37.83  ? 622 HOH B O   1 
HETATM 25862 O O   . HOH J 2 .   ? 2.901   -54.882 9.845   1.00 25.39  ? 623 HOH B O   1 
HETATM 25863 O O   . HOH J 2 .   ? 3.309   -52.218 10.367  1.00 26.78  ? 624 HOH B O   1 
HETATM 25864 O O   . HOH J 2 .   ? 12.865  -15.324 21.120  1.00 27.50  ? 625 HOH B O   1 
HETATM 25865 O O   . HOH J 2 .   ? 28.438  -62.227 -8.830  1.00 46.90  ? 626 HOH B O   1 
HETATM 25866 O O   . HOH J 2 .   ? 4.045   -48.609 -0.101  1.00 33.89  ? 627 HOH B O   1 
HETATM 25867 O O   . HOH J 2 .   ? -8.919  -43.304 10.821  1.00 39.78  ? 628 HOH B O   1 
HETATM 25868 O O   . HOH J 2 .   ? 0.889   -52.059 6.432   1.00 37.02  ? 629 HOH B O   1 
HETATM 25869 O O   . HOH J 2 .   ? 21.293  -51.749 17.876  1.00 43.36  ? 630 HOH B O   1 
HETATM 25870 O O   . HOH J 2 .   ? 12.150  -27.909 14.488  1.00 40.64  ? 631 HOH B O   1 
HETATM 25871 O O   . HOH J 2 .   ? 27.995  -35.373 -14.295 1.00 41.41  ? 632 HOH B O   1 
HETATM 25872 O O   . HOH J 2 .   ? 25.761  -36.057 28.164  1.00 47.44  ? 633 HOH B O   1 
HETATM 25873 O O   . HOH J 2 .   ? 25.468  -17.645 5.827   1.00 44.04  ? 634 HOH B O   1 
HETATM 25874 O O   . HOH J 2 .   ? 13.852  -32.576 20.038  1.00 37.53  ? 635 HOH B O   1 
HETATM 25875 O O   . HOH J 2 .   ? -6.882  -44.739 9.083   1.00 41.62  ? 636 HOH B O   1 
HETATM 25876 O O   . HOH J 2 .   ? 27.654  -37.203 30.592  1.00 41.45  ? 637 HOH B O   1 
HETATM 25877 O O   . HOH J 2 .   ? 4.669   -42.531 -5.195  1.00 30.09  ? 638 HOH B O   1 
HETATM 25878 O O   . HOH J 2 .   ? -4.115  -43.614 8.825   1.00 39.87  ? 639 HOH B O   1 
HETATM 25879 O O   . HOH J 2 .   ? -6.954  -31.276 5.562   1.00 41.55  ? 640 HOH B O   1 
HETATM 25880 O O   . HOH J 2 .   ? 34.928  -58.966 11.152  1.00 36.69  ? 641 HOH B O   1 
HETATM 25881 O O   . HOH J 2 .   ? 27.524  -20.951 2.761   1.00 48.13  ? 642 HOH B O   1 
HETATM 25882 O O   . HOH J 2 .   ? 26.080  -34.908 26.508  1.00 43.79  ? 643 HOH B O   1 
HETATM 25883 O O   . HOH J 2 .   ? 27.671  -38.277 -14.789 1.00 41.85  ? 644 HOH B O   1 
HETATM 25884 O O   . HOH J 2 .   ? 32.975  -22.359 26.283  1.00 43.15  ? 645 HOH B O   1 
HETATM 25885 O O   . HOH J 2 .   ? 1.483   -44.255 -6.210  1.00 34.39  ? 646 HOH B O   1 
HETATM 25886 O O   . HOH J 2 .   ? 23.201  -10.517 19.966  1.00 57.14  ? 647 HOH B O   1 
HETATM 25887 O O   . HOH J 2 .   ? 26.878  -28.505 30.378  1.00 33.47  ? 648 HOH B O   1 
HETATM 25888 O O   . HOH J 2 .   ? 3.339   -39.389 -19.300 1.00 62.44  ? 649 HOH B O   1 
HETATM 25889 O O   . HOH J 2 .   ? -8.793  -29.810 14.556  1.00 52.01  ? 650 HOH B O   1 
HETATM 25890 O O   . HOH J 2 .   ? 14.710  -10.263 13.646  1.00 47.23  ? 651 HOH B O   1 
HETATM 25891 O O   . HOH J 2 .   ? 0.612   -51.656 11.651  1.00 44.65  ? 652 HOH B O   1 
HETATM 25892 O O   . HOH J 2 .   ? 21.051  -55.327 24.684  1.00 48.56  ? 653 HOH B O   1 
HETATM 25893 O O   . HOH J 2 .   ? 28.087  -32.008 -10.236 1.00 41.81  ? 654 HOH B O   1 
HETATM 25894 O O   . HOH J 2 .   ? 31.074  -27.095 28.894  1.00 28.06  ? 655 HOH B O   1 
HETATM 25895 O O   . HOH J 2 .   ? 28.793  -28.232 31.895  1.00 42.55  ? 656 HOH B O   1 
HETATM 25896 O O   . HOH J 2 .   ? -2.700  -61.403 4.899   1.00 29.81  ? 657 HOH B O   1 
HETATM 25897 O O   . HOH J 2 .   ? 27.933  -33.291 -12.605 1.00 42.50  ? 658 HOH B O   1 
HETATM 25898 O O   . HOH J 2 .   ? -3.142  -44.228 10.755  1.00 41.04  ? 659 HOH B O   1 
HETATM 25899 O O   . HOH J 2 .   ? 30.179  -28.331 30.534  1.00 33.41  ? 660 HOH B O   1 
HETATM 25900 O O   . HOH J 2 .   ? 6.705   -48.798 -6.375  1.00 36.91  ? 661 HOH B O   1 
HETATM 25901 O O   . HOH J 2 .   ? 34.638  -22.685 25.184  1.00 32.22  ? 662 HOH B O   1 
HETATM 25902 O O   . HOH J 2 .   ? 28.153  -41.696 30.058  1.00 47.16  ? 663 HOH B O   1 
HETATM 25903 O O   . HOH J 2 .   ? 27.444  -44.119 31.015  1.00 50.21  ? 664 HOH B O   1 
HETATM 25904 O O   . HOH J 2 .   ? 32.034  -28.505 31.908  1.00 43.31  ? 665 HOH B O   1 
HETATM 25905 O O   . HOH J 2 .   ? 18.152  -6.645  12.723  1.00 52.24  ? 666 HOH B O   1 
HETATM 25906 O O   . HOH J 2 .   ? 32.876  -29.453 33.849  1.00 43.38  ? 667 HOH B O   1 
HETATM 25907 O O   . HOH K 2 .   ? 32.350  -28.139 -7.497  1.00 55.33  ? 501 HOH C O   1 
HETATM 25908 O O   . HOH K 2 .   ? 64.878  -11.203 12.293  1.00 53.45  ? 502 HOH C O   1 
HETATM 25909 O O   . HOH K 2 .   ? 31.121  -21.282 -2.077  1.00 45.01  ? 503 HOH C O   1 
HETATM 25910 O O   . HOH K 2 .   ? 63.699  -20.046 14.296  1.00 37.80  ? 504 HOH C O   1 
HETATM 25911 O O   . HOH K 2 .   ? 56.047  -42.471 15.548  1.00 31.37  ? 505 HOH C O   1 
HETATM 25912 O O   . HOH K 2 .   ? 53.846  -46.200 -7.196  1.00 30.59  ? 506 HOH C O   1 
HETATM 25913 O O   . HOH K 2 .   ? 58.375  -5.946  11.072  1.00 44.77  ? 507 HOH C O   1 
HETATM 25914 O O   . HOH K 2 .   ? 56.147  -34.523 -1.791  1.00 25.44  ? 508 HOH C O   1 
HETATM 25915 O O   . HOH K 2 .   ? 36.754  -28.283 -6.179  1.00 50.90  ? 509 HOH C O   1 
HETATM 25916 O O   . HOH K 2 .   ? 53.432  -41.338 18.799  1.00 36.48  ? 510 HOH C O   1 
HETATM 25917 O O   . HOH K 2 .   ? 56.997  -21.032 -22.116 1.00 46.56  ? 511 HOH C O   1 
HETATM 25918 O O   . HOH K 2 .   ? 38.183  -49.015 7.829   1.00 51.71  ? 512 HOH C O   1 
HETATM 25919 O O   . HOH K 2 .   ? 47.930  -58.621 25.789  1.00 61.20  ? 513 HOH C O   1 
HETATM 25920 O O   . HOH K 2 .   ? 45.029  -7.887  4.708   1.00 27.03  ? 514 HOH C O   1 
HETATM 25921 O O   . HOH K 2 .   ? 47.565  -60.839 20.867  1.00 43.18  ? 515 HOH C O   1 
HETATM 25922 O O   . HOH K 2 .   ? 56.783  -19.940 -2.543  1.00 31.62  ? 516 HOH C O   1 
HETATM 25923 O O   . HOH K 2 .   ? 71.996  -32.144 5.185   1.00 45.63  ? 517 HOH C O   1 
HETATM 25924 O O   . HOH K 2 .   ? 35.335  1.485   11.238  1.00 33.43  ? 518 HOH C O   1 
HETATM 25925 O O   . HOH K 2 .   ? 50.227  -29.154 24.520  1.00 47.91  ? 519 HOH C O   1 
HETATM 25926 O O   . HOH K 2 .   ? 47.373  -53.615 1.288   1.00 47.51  ? 520 HOH C O   1 
HETATM 25927 O O   . HOH K 2 .   ? 70.135  -29.324 6.537   1.00 34.75  ? 521 HOH C O   1 
HETATM 25928 O O   . HOH K 2 .   ? 55.413  -5.553  4.444   1.00 29.43  ? 522 HOH C O   1 
HETATM 25929 O O   . HOH K 2 .   ? 68.516  -38.577 13.877  1.00 19.98  ? 523 HOH C O   1 
HETATM 25930 O O   . HOH K 2 .   ? 54.857  -49.753 28.355  1.00 40.71  ? 524 HOH C O   1 
HETATM 25931 O O   . HOH K 2 .   ? 48.733  -18.648 19.928  1.00 49.04  ? 525 HOH C O   1 
HETATM 25932 O O   . HOH K 2 .   ? 37.934  1.076   10.268  1.00 28.80  ? 526 HOH C O   1 
HETATM 25933 O O   . HOH K 2 .   ? 52.139  -45.512 28.426  1.00 38.61  ? 527 HOH C O   1 
HETATM 25934 O O   . HOH K 2 .   ? 50.650  -36.053 -15.783 1.00 32.57  ? 528 HOH C O   1 
HETATM 25935 O O   . HOH K 2 .   ? 55.771  -18.342 18.508  1.00 37.89  ? 529 HOH C O   1 
HETATM 25936 O O   . HOH K 2 .   ? 35.628  -49.732 10.094  1.00 38.53  ? 530 HOH C O   1 
HETATM 25937 O O   . HOH K 2 .   ? 48.398  -39.000 5.600   1.00 40.82  ? 531 HOH C O   1 
HETATM 25938 O O   . HOH K 2 .   ? 57.328  -54.149 21.581  1.00 38.89  ? 532 HOH C O   1 
HETATM 25939 O O   . HOH K 2 .   ? 45.385  -60.649 14.528  1.00 39.07  ? 533 HOH C O   1 
HETATM 25940 O O   . HOH K 2 .   ? 37.944  -26.416 -0.553  1.00 42.10  ? 534 HOH C O   1 
HETATM 25941 O O   . HOH K 2 .   ? 62.388  -43.878 -12.427 1.00 31.13  ? 535 HOH C O   1 
HETATM 25942 O O   . HOH K 2 .   ? 48.089  -35.876 19.946  1.00 45.79  ? 536 HOH C O   1 
HETATM 25943 O O   . HOH K 2 .   ? 46.346  -48.109 7.905   1.00 40.45  ? 537 HOH C O   1 
HETATM 25944 O O   . HOH K 2 .   ? 39.662  -29.754 -15.526 1.00 49.64  ? 538 HOH C O   1 
HETATM 25945 O O   . HOH K 2 .   ? 56.590  -48.930 5.800   1.00 29.32  ? 539 HOH C O   1 
HETATM 25946 O O   . HOH K 2 .   ? 56.713  -27.581 -4.365  1.00 39.00  ? 540 HOH C O   1 
HETATM 25947 O O   . HOH K 2 .   ? 33.332  -13.084 9.766   1.00 35.64  ? 541 HOH C O   1 
HETATM 25948 O O   . HOH K 2 .   ? 39.382  -51.593 6.624   1.00 47.12  ? 542 HOH C O   1 
HETATM 25949 O O   . HOH K 2 .   ? 57.930  -41.097 17.754  1.00 36.28  ? 543 HOH C O   1 
HETATM 25950 O O   . HOH K 2 .   ? 55.430  -8.506  12.480  1.00 32.50  ? 544 HOH C O   1 
HETATM 25951 O O   . HOH K 2 .   ? 68.167  -22.176 6.584   1.00 29.64  ? 545 HOH C O   1 
HETATM 25952 O O   . HOH K 2 .   ? 54.374  -22.018 9.851   1.00 27.38  ? 546 HOH C O   1 
HETATM 25953 O O   . HOH K 2 .   ? 50.115  -53.937 30.590  1.00 46.92  ? 547 HOH C O   1 
HETATM 25954 O O   . HOH K 2 .   ? 50.776  -41.061 -7.866  1.00 34.34  ? 548 HOH C O   1 
HETATM 25955 O O   . HOH K 2 .   ? 56.373  -41.274 7.641   1.00 44.31  ? 549 HOH C O   1 
HETATM 25956 O O   . HOH K 2 .   ? 42.546  -5.011  -4.734  1.00 31.30  ? 550 HOH C O   1 
HETATM 25957 O O   . HOH K 2 .   ? 46.786  -5.062  1.159   1.00 34.53  ? 551 HOH C O   1 
HETATM 25958 O O   . HOH K 2 .   ? 48.273  -35.492 -7.750  1.00 32.33  ? 552 HOH C O   1 
HETATM 25959 O O   . HOH K 2 .   ? 60.903  -6.718  8.770   1.00 34.70  ? 553 HOH C O   1 
HETATM 25960 O O   . HOH K 2 .   ? 58.641  -20.033 0.658   1.00 27.13  ? 554 HOH C O   1 
HETATM 25961 O O   . HOH K 2 .   ? 55.950  -46.185 -10.568 1.00 27.33  ? 555 HOH C O   1 
HETATM 25962 O O   . HOH K 2 .   ? 46.596  -5.056  4.611   1.00 30.67  ? 556 HOH C O   1 
HETATM 25963 O O   . HOH K 2 .   ? 58.005  -24.921 20.634  1.00 30.41  ? 557 HOH C O   1 
HETATM 25964 O O   . HOH K 2 .   ? 58.959  -17.961 -8.275  1.00 32.33  ? 558 HOH C O   1 
HETATM 25965 O O   . HOH K 2 .   ? 35.128  -57.634 17.540  1.00 43.12  ? 559 HOH C O   1 
HETATM 25966 O O   . HOH K 2 .   ? 42.554  -20.502 1.265   1.00 25.18  ? 560 HOH C O   1 
HETATM 25967 O O   . HOH K 2 .   ? 45.300  -9.064  -10.323 1.00 43.02  ? 561 HOH C O   1 
HETATM 25968 O O   . HOH K 2 .   ? 37.563  -2.014  4.417   1.00 28.37  ? 562 HOH C O   1 
HETATM 25969 O O   . HOH K 2 .   ? 51.351  -24.462 3.022   1.00 19.86  ? 563 HOH C O   1 
HETATM 25970 O O   . HOH K 2 .   ? 57.104  -29.938 4.498   1.00 21.67  ? 564 HOH C O   1 
HETATM 25971 O O   . HOH K 2 .   ? 49.612  -52.409 3.335   1.00 43.50  ? 565 HOH C O   1 
HETATM 25972 O O   . HOH K 2 .   ? 67.682  -28.960 11.855  1.00 27.73  ? 566 HOH C O   1 
HETATM 25973 O O   . HOH K 2 .   ? 39.859  -54.384 1.569   1.00 40.89  ? 567 HOH C O   1 
HETATM 25974 O O   . HOH K 2 .   ? 44.173  -4.081  -1.712  1.00 34.78  ? 568 HOH C O   1 
HETATM 25975 O O   . HOH K 2 .   ? 46.800  -34.187 -1.907  1.00 34.92  ? 569 HOH C O   1 
HETATM 25976 O O   . HOH K 2 .   ? 65.888  -44.751 17.587  1.00 30.84  ? 570 HOH C O   1 
HETATM 25977 O O   . HOH K 2 .   ? 48.533  -9.779  25.505  1.00 33.61  ? 571 HOH C O   1 
HETATM 25978 O O   . HOH K 2 .   ? 55.655  -55.213 14.740  1.00 28.99  ? 572 HOH C O   1 
HETATM 25979 O O   . HOH K 2 .   ? 54.128  -43.662 13.973  1.00 34.03  ? 573 HOH C O   1 
HETATM 25980 O O   . HOH K 2 .   ? 57.845  -17.248 -10.921 1.00 39.04  ? 574 HOH C O   1 
HETATM 25981 O O   . HOH K 2 .   ? 36.465  0.500   14.941  1.00 43.22  ? 575 HOH C O   1 
HETATM 25982 O O   . HOH K 2 .   ? 66.728  -38.126 -6.271  1.00 26.62  ? 576 HOH C O   1 
HETATM 25983 O O   . HOH K 2 .   ? 56.961  -60.970 14.830  1.00 27.29  ? 577 HOH C O   1 
HETATM 25984 O O   . HOH K 2 .   ? 53.758  -39.392 22.334  1.00 36.48  ? 578 HOH C O   1 
HETATM 25985 O O   . HOH K 2 .   ? 52.479  -24.192 0.427   1.00 22.71  ? 579 HOH C O   1 
HETATM 25986 O O   . HOH K 2 .   ? 75.340  -33.113 20.405  1.00 53.33  ? 580 HOH C O   1 
HETATM 25987 O O   . HOH K 2 .   ? 38.068  -33.615 -14.752 1.00 46.25  ? 581 HOH C O   1 
HETATM 25988 O O   . HOH K 2 .   ? 34.344  -27.763 3.926   1.00 41.17  ? 582 HOH C O   1 
HETATM 25989 O O   . HOH K 2 .   ? 60.702  -31.927 -19.353 1.00 40.08  ? 583 HOH C O   1 
HETATM 25990 O O   . HOH K 2 .   ? 72.217  -30.390 4.161   1.00 35.17  ? 584 HOH C O   1 
HETATM 25991 O O   . HOH K 2 .   ? 68.831  -33.529 -7.579  1.00 31.15  ? 585 HOH C O   1 
HETATM 25992 O O   . HOH K 2 .   ? 39.041  -50.487 1.128   1.00 39.78  ? 586 HOH C O   1 
HETATM 25993 O O   . HOH K 2 .   ? 58.641  -44.453 25.026  1.00 32.49  ? 587 HOH C O   1 
HETATM 25994 O O   . HOH K 2 .   ? 54.047  -41.287 -4.478  1.00 48.98  ? 588 HOH C O   1 
HETATM 25995 O O   . HOH K 2 .   ? 63.269  -16.326 9.850   1.00 25.19  ? 589 HOH C O   1 
HETATM 25996 O O   . HOH K 2 .   ? 59.348  -18.732 11.801  1.00 27.26  ? 590 HOH C O   1 
HETATM 25997 O O   . HOH K 2 .   ? 33.050  -50.661 24.516  1.00 55.71  ? 591 HOH C O   1 
HETATM 25998 O O   . HOH K 2 .   ? 44.051  -2.293  17.571  1.00 43.47  ? 592 HOH C O   1 
HETATM 25999 O O   . HOH K 2 .   ? 59.875  -17.245 0.546   1.00 27.67  ? 593 HOH C O   1 
HETATM 26000 O O   . HOH K 2 .   ? 49.945  -30.808 2.215   1.00 40.30  ? 594 HOH C O   1 
HETATM 26001 O O   . HOH K 2 .   ? 54.512  -32.866 16.994  1.00 41.07  ? 595 HOH C O   1 
HETATM 26002 O O   . HOH K 2 .   ? 66.998  -6.774  16.324  1.00 46.80  ? 596 HOH C O   1 
HETATM 26003 O O   . HOH K 2 .   ? 53.800  -30.669 15.491  1.00 35.13  ? 597 HOH C O   1 
HETATM 26004 O O   . HOH K 2 .   ? 76.500  -30.832 17.408  1.00 50.94  ? 598 HOH C O   1 
HETATM 26005 O O   . HOH K 2 .   ? 32.660  -16.356 2.161   1.00 37.49  ? 599 HOH C O   1 
HETATM 26006 O O   . HOH K 2 .   ? 43.848  -1.709  10.309  1.00 27.38  ? 600 HOH C O   1 
HETATM 26007 O O   . HOH K 2 .   ? 65.631  -39.568 -8.721  1.00 31.09  ? 601 HOH C O   1 
HETATM 26008 O O   . HOH K 2 .   ? 40.651  -35.276 -15.564 1.00 47.17  ? 602 HOH C O   1 
HETATM 26009 O O   . HOH K 2 .   ? 60.682  -14.326 17.532  1.00 30.94  ? 603 HOH C O   1 
HETATM 26010 O O   . HOH K 2 .   ? 43.552  -40.215 -9.807  1.00 40.08  ? 604 HOH C O   1 
HETATM 26011 O O   . HOH K 2 .   ? 40.937  -7.160  -6.018  1.00 34.21  ? 605 HOH C O   1 
HETATM 26012 O O   . HOH K 2 .   ? 56.722  -10.043 -2.285  1.00 34.12  ? 606 HOH C O   1 
HETATM 26013 O O   . HOH K 2 .   ? 60.994  -41.396 -18.024 1.00 45.98  ? 607 HOH C O   1 
HETATM 26014 O O   . HOH K 2 .   ? 41.518  -1.215  20.212  1.00 46.69  ? 608 HOH C O   1 
HETATM 26015 O O   . HOH K 2 .   ? 61.383  -20.424 12.357  1.00 27.88  ? 609 HOH C O   1 
HETATM 26016 O O   . HOH K 2 .   ? 67.905  -46.912 17.541  1.00 34.42  ? 610 HOH C O   1 
HETATM 26017 O O   . HOH K 2 .   ? 38.989  -42.959 29.970  1.00 45.22  ? 611 HOH C O   1 
HETATM 26018 O O   . HOH K 2 .   ? 65.162  -9.827  3.372   1.00 27.76  ? 612 HOH C O   1 
HETATM 26019 O O   . HOH K 2 .   ? 74.556  -27.899 10.577  1.00 47.51  ? 613 HOH C O   1 
HETATM 26020 O O   . HOH K 2 .   ? 68.375  -11.177 2.830   1.00 26.52  ? 614 HOH C O   1 
HETATM 26021 O O   . HOH K 2 .   ? 47.489  -25.824 21.930  1.00 45.27  ? 615 HOH C O   1 
HETATM 26022 O O   . HOH K 2 .   ? 50.325  -0.696  13.200  1.00 39.24  ? 616 HOH C O   1 
HETATM 26023 O O   . HOH K 2 .   ? 48.088  -5.634  -9.191  1.00 36.15  ? 617 HOH C O   1 
HETATM 26024 O O   . HOH K 2 .   ? 73.718  -24.797 -2.926  1.00 44.36  ? 618 HOH C O   1 
HETATM 26025 O O   . HOH K 2 .   ? 62.848  -18.985 10.130  1.00 26.99  ? 619 HOH C O   1 
HETATM 26026 O O   . HOH K 2 .   ? 51.636  -2.570  -4.038  1.00 38.74  ? 620 HOH C O   1 
HETATM 26027 O O   . HOH K 2 .   ? 54.260  -58.073 18.579  1.00 43.29  ? 621 HOH C O   1 
HETATM 26028 O O   . HOH K 2 .   ? 49.606  -20.371 -26.545 1.00 41.70  ? 622 HOH C O   1 
HETATM 26029 O O   . HOH K 2 .   ? 58.707  -45.154 -15.333 1.00 32.69  ? 623 HOH C O   1 
HETATM 26030 O O   . HOH K 2 .   ? 61.552  -28.911 28.904  1.00 42.01  ? 624 HOH C O   1 
HETATM 26031 O O   . HOH K 2 .   ? 72.200  -29.252 5.974   1.00 57.66  ? 625 HOH C O   1 
HETATM 26032 O O   . HOH K 2 .   ? 66.160  -38.104 -11.372 1.00 30.84  ? 626 HOH C O   1 
HETATM 26033 O O   . HOH K 2 .   ? 49.127  -37.516 11.770  1.00 49.00  ? 627 HOH C O   1 
HETATM 26034 O O   . HOH K 2 .   ? 29.724  -13.424 8.220   1.00 49.01  ? 628 HOH C O   1 
HETATM 26035 O O   . HOH K 2 .   ? 39.992  -54.946 -1.804  1.00 45.48  ? 629 HOH C O   1 
HETATM 26036 O O   . HOH K 2 .   ? 71.383  -25.153 21.913  1.00 41.02  ? 630 HOH C O   1 
HETATM 26037 O O   . HOH K 2 .   ? 36.038  -60.681 15.394  1.00 54.64  ? 631 HOH C O   1 
HETATM 26038 O O   . HOH K 2 .   ? 50.037  -37.271 7.604   1.00 41.59  ? 632 HOH C O   1 
HETATM 26039 O O   . HOH K 2 .   ? 30.129  -10.486 6.680   1.00 53.39  ? 633 HOH C O   1 
HETATM 26040 O O   . HOH K 2 .   ? 53.140  -56.124 20.031  1.00 37.86  ? 634 HOH C O   1 
HETATM 26041 O O   . HOH K 2 .   ? 75.963  -27.463 0.295   1.00 28.16  ? 635 HOH C O   1 
HETATM 26042 O O   . HOH K 2 .   ? 45.556  -35.588 12.718  1.00 47.76  ? 636 HOH C O   1 
HETATM 26043 O O   . HOH K 2 .   ? 50.951  -57.929 25.612  1.00 52.15  ? 637 HOH C O   1 
HETATM 26044 O O   . HOH K 2 .   ? 56.544  -24.480 26.222  1.00 42.02  ? 638 HOH C O   1 
HETATM 26045 O O   . HOH K 2 .   ? 61.206  -33.239 -17.384 1.00 44.98  ? 639 HOH C O   1 
HETATM 26046 O O   . HOH K 2 .   ? 75.185  -29.780 -8.511  1.00 52.50  ? 640 HOH C O   1 
HETATM 26047 O O   . HOH K 2 .   ? 36.155  -58.908 13.902  1.00 47.98  ? 641 HOH C O   1 
HETATM 26048 O O   . HOH K 2 .   ? 28.997  -11.763 5.582   1.00 47.11  ? 642 HOH C O   1 
HETATM 26049 O O   . HOH K 2 .   ? 56.353  -25.032 23.648  1.00 37.55  ? 643 HOH C O   1 
HETATM 26050 O O   . HOH K 2 .   ? 29.195  -19.647 2.162   1.00 42.51  ? 644 HOH C O   1 
HETATM 26051 O O   . HOH K 2 .   ? 46.905  -2.040  3.132   1.00 38.84  ? 645 HOH C O   1 
HETATM 26052 O O   . HOH K 2 .   ? 30.595  -12.377 9.920   1.00 39.38  ? 646 HOH C O   1 
HETATM 26053 O O   . HOH K 2 .   ? 69.650  -47.409 17.963  1.00 44.29  ? 647 HOH C O   1 
HETATM 26054 O O   . HOH K 2 .   ? 51.425  -30.915 10.419  1.00 39.19  ? 648 HOH C O   1 
HETATM 26055 O O   . HOH K 2 .   ? 59.651  -52.074 21.546  1.00 49.55  ? 649 HOH C O   1 
HETATM 26056 O O   . HOH K 2 .   ? 50.267  -32.618 9.785   1.00 43.73  ? 650 HOH C O   1 
HETATM 26057 O O   . HOH K 2 .   ? 43.549  0.329   8.030   1.00 39.28  ? 651 HOH C O   1 
HETATM 26058 O O   . HOH K 2 .   ? 41.151  -7.314  -8.736  1.00 37.64  ? 652 HOH C O   1 
HETATM 26059 O O   . HOH K 2 .   ? 46.763  -37.005 10.880  1.00 50.15  ? 653 HOH C O   1 
HETATM 26060 O O   . HOH K 2 .   ? 65.412  -19.865 11.419  1.00 38.96  ? 654 HOH C O   1 
HETATM 26061 O O   . HOH K 2 .   ? 44.983  -6.824  -9.731  1.00 50.69  ? 655 HOH C O   1 
HETATM 26062 O O   . HOH K 2 .   ? 60.192  -15.378 -1.283  1.00 32.45  ? 656 HOH C O   1 
HETATM 26063 O O   . HOH K 2 .   ? 46.045  -0.128  2.072   1.00 46.34  ? 657 HOH C O   1 
HETATM 26064 O O   . HOH K 2 .   ? 32.310  -29.560 2.892   1.00 60.31  ? 658 HOH C O   1 
HETATM 26065 O O   . HOH K 2 .   ? 28.781  -12.710 10.667  1.00 43.18  ? 659 HOH C O   1 
HETATM 26066 O O   . HOH K 2 .   ? 43.075  -44.390 -8.214  1.00 41.00  ? 660 HOH C O   1 
HETATM 26067 O O   . HOH L 2 .   ? 21.009  5.991   -2.457  1.00 42.02  ? 501 HOH D O   1 
HETATM 26068 O O   . HOH L 2 .   ? 38.823  21.128  21.028  1.00 49.35  ? 502 HOH D O   1 
HETATM 26069 O O   . HOH L 2 .   ? 34.058  36.840  14.857  1.00 29.09  ? 503 HOH D O   1 
HETATM 26070 O O   . HOH L 2 .   ? 32.362  2.682   13.020  1.00 35.02  ? 504 HOH D O   1 
HETATM 26071 O O   . HOH L 2 .   ? 19.573  10.508  3.819   1.00 43.01  ? 505 HOH D O   1 
HETATM 26072 O O   . HOH L 2 .   ? 22.311  25.886  -4.745  1.00 51.88  ? 506 HOH D O   1 
HETATM 26073 O O   . HOH L 2 .   ? 44.107  38.347  -13.210 1.00 43.93  ? 507 HOH D O   1 
HETATM 26074 O O   . HOH L 2 .   ? 20.319  36.015  -11.766 1.00 37.70  ? 508 HOH D O   1 
HETATM 26075 O O   . HOH L 2 .   ? 21.045  4.141   -16.167 1.00 54.13  ? 509 HOH D O   1 
HETATM 26076 O O   . HOH L 2 .   ? 25.825  4.553   6.328   1.00 41.72  ? 510 HOH D O   1 
HETATM 26077 O O   . HOH L 2 .   ? 20.013  34.222  -12.783 1.00 39.18  ? 511 HOH D O   1 
HETATM 26078 O O   . HOH L 2 .   ? 39.255  1.621   11.841  1.00 34.60  ? 512 HOH D O   1 
HETATM 26079 O O   . HOH L 2 .   ? 37.491  22.241  15.133  1.00 46.26  ? 513 HOH D O   1 
HETATM 26080 O O   . HOH L 2 .   ? 18.969  36.836  23.078  1.00 38.85  ? 514 HOH D O   1 
HETATM 26081 O O   . HOH L 2 .   ? 19.670  35.939  -2.390  1.00 32.75  ? 515 HOH D O   1 
HETATM 26082 O O   . HOH L 2 .   ? 24.852  45.479  -11.224 1.00 27.95  ? 516 HOH D O   1 
HETATM 26083 O O   . HOH L 2 .   ? 28.481  0.014   -6.494  1.00 27.32  ? 517 HOH D O   1 
HETATM 26084 O O   . HOH L 2 .   ? 26.223  22.368  27.722  1.00 38.84  ? 518 HOH D O   1 
HETATM 26085 O O   . HOH L 2 .   ? 18.568  40.127  17.869  1.00 24.18  ? 519 HOH D O   1 
HETATM 26086 O O   . HOH L 2 .   ? 26.540  11.174  3.371   1.00 32.80  ? 520 HOH D O   1 
HETATM 26087 O O   . HOH L 2 .   ? 6.804   19.358  -17.363 1.00 51.94  ? 521 HOH D O   1 
HETATM 26088 O O   . HOH L 2 .   ? 41.620  21.864  16.898  1.00 45.16  ? 522 HOH D O   1 
HETATM 26089 O O   . HOH L 2 .   ? 19.570  9.502   -4.858  1.00 47.52  ? 523 HOH D O   1 
HETATM 26090 O O   . HOH L 2 .   ? 28.579  28.690  1.628   1.00 25.03  ? 524 HOH D O   1 
HETATM 26091 O O   . HOH L 2 .   ? 8.840   32.367  -5.143  1.00 37.38  ? 525 HOH D O   1 
HETATM 26092 O O   . HOH L 2 .   ? 41.331  24.706  -12.099 1.00 46.88  ? 526 HOH D O   1 
HETATM 26093 O O   . HOH L 2 .   ? 24.540  17.287  -22.682 1.00 61.11  ? 527 HOH D O   1 
HETATM 26094 O O   . HOH L 2 .   ? 16.761  32.838  9.144   1.00 37.97  ? 528 HOH D O   1 
HETATM 26095 O O   . HOH L 2 .   ? 17.151  24.467  11.939  1.00 32.36  ? 529 HOH D O   1 
HETATM 26096 O O   . HOH L 2 .   ? 23.799  10.132  7.971   1.00 48.20  ? 530 HOH D O   1 
HETATM 26097 O O   . HOH L 2 .   ? 46.000  14.425  -4.969  1.00 31.58  ? 531 HOH D O   1 
HETATM 26098 O O   . HOH L 2 .   ? 24.719  35.737  -23.937 1.00 42.72  ? 532 HOH D O   1 
HETATM 26099 O O   . HOH L 2 .   ? 17.282  26.198  20.516  1.00 29.18  ? 533 HOH D O   1 
HETATM 26100 O O   . HOH L 2 .   ? 29.130  26.156  10.054  1.00 37.42  ? 534 HOH D O   1 
HETATM 26101 O O   . HOH L 2 .   ? 30.833  -1.619  -4.430  1.00 46.19  ? 535 HOH D O   1 
HETATM 26102 O O   . HOH L 2 .   ? 19.070  33.494  10.884  1.00 29.12  ? 536 HOH D O   1 
HETATM 26103 O O   . HOH L 2 .   ? 12.044  17.290  12.059  1.00 43.49  ? 537 HOH D O   1 
HETATM 26104 O O   . HOH L 2 .   ? 22.767  37.575  -12.656 1.00 36.05  ? 538 HOH D O   1 
HETATM 26105 O O   . HOH L 2 .   ? 29.018  41.491  -17.104 1.00 34.56  ? 539 HOH D O   1 
HETATM 26106 O O   . HOH L 2 .   ? 28.980  28.387  18.965  1.00 26.38  ? 540 HOH D O   1 
HETATM 26107 O O   . HOH L 2 .   ? 26.861  40.453  12.632  1.00 38.67  ? 541 HOH D O   1 
HETATM 26108 O O   . HOH L 2 .   ? 19.675  35.353  -7.335  1.00 34.36  ? 542 HOH D O   1 
HETATM 26109 O O   . HOH L 2 .   ? 36.761  27.685  7.929   1.00 31.56  ? 543 HOH D O   1 
HETATM 26110 O O   . HOH L 2 .   ? 39.133  5.732   1.192   1.00 21.95  ? 544 HOH D O   1 
HETATM 26111 O O   . HOH L 2 .   ? 14.045  40.506  -1.305  1.00 25.64  ? 545 HOH D O   1 
HETATM 26112 O O   . HOH L 2 .   ? 39.176  18.772  -10.513 1.00 40.17  ? 546 HOH D O   1 
HETATM 26113 O O   . HOH L 2 .   ? 36.220  -3.907  2.172   1.00 27.05  ? 547 HOH D O   1 
HETATM 26114 O O   . HOH L 2 .   ? 41.946  33.241  0.776   1.00 45.34  ? 548 HOH D O   1 
HETATM 26115 O O   . HOH L 2 .   ? 44.988  22.866  -9.096  1.00 33.48  ? 549 HOH D O   1 
HETATM 26116 O O   . HOH L 2 .   ? 30.425  43.925  -6.707  1.00 28.02  ? 550 HOH D O   1 
HETATM 26117 O O   . HOH L 2 .   ? 39.843  24.419  -4.831  1.00 31.42  ? 551 HOH D O   1 
HETATM 26118 O O   . HOH L 2 .   ? 31.982  -6.974  -2.166  1.00 35.03  ? 552 HOH D O   1 
HETATM 26119 O O   . HOH L 2 .   ? 2.801   41.009  -21.254 1.00 33.85  ? 553 HOH D O   1 
HETATM 26120 O O   . HOH L 2 .   ? 17.137  35.871  -23.574 1.00 33.32  ? 554 HOH D O   1 
HETATM 26121 O O   . HOH L 2 .   ? 4.336   28.848  3.319   1.00 52.45  ? 555 HOH D O   1 
HETATM 26122 O O   . HOH L 2 .   ? 46.637  5.469   2.989   1.00 46.83  ? 556 HOH D O   1 
HETATM 26123 O O   . HOH L 2 .   ? 31.263  39.082  14.388  1.00 40.01  ? 557 HOH D O   1 
HETATM 26124 O O   . HOH L 2 .   ? 36.673  37.012  -4.148  1.00 23.37  ? 558 HOH D O   1 
HETATM 26125 O O   . HOH L 2 .   ? 29.439  20.723  2.195   1.00 26.09  ? 559 HOH D O   1 
HETATM 26126 O O   . HOH L 2 .   ? 23.884  30.426  7.765   1.00 28.44  ? 560 HOH D O   1 
HETATM 26127 O O   . HOH L 2 .   ? 35.805  27.507  -14.010 1.00 32.19  ? 561 HOH D O   1 
HETATM 26128 O O   . HOH L 2 .   ? 35.984  21.462  9.431   1.00 27.74  ? 562 HOH D O   1 
HETATM 26129 O O   . HOH L 2 .   ? 39.012  -4.163  1.021   1.00 31.96  ? 563 HOH D O   1 
HETATM 26130 O O   . HOH L 2 .   ? 46.628  18.131  -14.855 1.00 41.58  ? 564 HOH D O   1 
HETATM 26131 O O   . HOH L 2 .   ? 37.348  43.265  1.285   1.00 38.51  ? 565 HOH D O   1 
HETATM 26132 O O   . HOH L 2 .   ? 41.106  2.378   7.578   1.00 43.94  ? 566 HOH D O   1 
HETATM 26133 O O   . HOH L 2 .   ? 5.981   48.675  -11.183 1.00 32.15  ? 567 HOH D O   1 
HETATM 26134 O O   . HOH L 2 .   ? 17.530  7.533   7.108   1.00 53.19  ? 568 HOH D O   1 
HETATM 26135 O O   . HOH L 2 .   ? 40.161  39.650  -15.065 1.00 34.97  ? 569 HOH D O   1 
HETATM 26136 O O   . HOH L 2 .   ? 44.330  25.796  -1.495  1.00 22.76  ? 570 HOH D O   1 
HETATM 26137 O O   . HOH L 2 .   ? 47.804  22.657  5.961   1.00 32.08  ? 571 HOH D O   1 
HETATM 26138 O O   . HOH L 2 .   ? 41.900  30.549  2.716   1.00 25.28  ? 572 HOH D O   1 
HETATM 26139 O O   . HOH L 2 .   ? 24.562  10.920  -3.339  1.00 38.92  ? 573 HOH D O   1 
HETATM 26140 O O   . HOH L 2 .   ? 25.952  51.610  -3.903  1.00 28.93  ? 574 HOH D O   1 
HETATM 26141 O O   . HOH L 2 .   ? 19.784  31.452  -3.924  1.00 52.66  ? 575 HOH D O   1 
HETATM 26142 O O   . HOH L 2 .   ? 32.253  16.221  -11.384 1.00 41.69  ? 576 HOH D O   1 
HETATM 26143 O O   . HOH L 2 .   ? 28.326  43.774  11.002  1.00 33.04  ? 577 HOH D O   1 
HETATM 26144 O O   . HOH L 2 .   ? 40.084  26.839  4.373   1.00 29.99  ? 578 HOH D O   1 
HETATM 26145 O O   . HOH L 2 .   ? 12.938  36.867  15.000  1.00 27.21  ? 579 HOH D O   1 
HETATM 26146 O O   . HOH L 2 .   ? 12.973  30.099  17.403  1.00 31.59  ? 580 HOH D O   1 
HETATM 26147 O O   . HOH L 2 .   ? 19.582  18.268  -25.749 1.00 56.23  ? 581 HOH D O   1 
HETATM 26148 O O   . HOH L 2 .   ? 37.555  40.699  4.114   1.00 31.53  ? 582 HOH D O   1 
HETATM 26149 O O   . HOH L 2 .   ? 49.899  18.520  -2.094  1.00 33.36  ? 583 HOH D O   1 
HETATM 26150 O O   . HOH L 2 .   ? -2.987  31.915  -27.493 1.00 44.35  ? 584 HOH D O   1 
HETATM 26151 O O   . HOH L 2 .   ? 41.703  5.056   2.081   1.00 24.47  ? 585 HOH D O   1 
HETATM 26152 O O   . HOH L 2 .   ? 31.163  46.789  2.627   1.00 34.11  ? 586 HOH D O   1 
HETATM 26153 O O   . HOH L 2 .   ? 49.616  21.845  -3.112  1.00 38.53  ? 587 HOH D O   1 
HETATM 26154 O O   . HOH L 2 .   ? 41.532  16.297  16.389  1.00 37.15  ? 588 HOH D O   1 
HETATM 26155 O O   . HOH L 2 .   ? 41.946  28.322  1.148   1.00 26.37  ? 589 HOH D O   1 
HETATM 26156 O O   . HOH L 2 .   ? 27.583  28.677  7.752   1.00 25.73  ? 590 HOH D O   1 
HETATM 26157 O O   . HOH L 2 .   ? 27.958  36.641  19.010  1.00 31.46  ? 591 HOH D O   1 
HETATM 26158 O O   . HOH L 2 .   ? 31.696  33.325  11.887  1.00 22.82  ? 592 HOH D O   1 
HETATM 26159 O O   . HOH L 2 .   ? -0.289  34.715  -25.184 1.00 37.14  ? 593 HOH D O   1 
HETATM 26160 O O   . HOH L 2 .   ? 46.941  12.363  3.611   1.00 29.58  ? 594 HOH D O   1 
HETATM 26161 O O   . HOH L 2 .   ? 35.626  33.101  -21.259 1.00 41.21  ? 595 HOH D O   1 
HETATM 26162 O O   . HOH L 2 .   ? 24.737  40.166  14.489  1.00 31.51  ? 596 HOH D O   1 
HETATM 26163 O O   . HOH L 2 .   ? 35.516  40.134  0.919   1.00 29.14  ? 597 HOH D O   1 
HETATM 26164 O O   . HOH L 2 .   ? 14.419  6.586   6.024   1.00 44.92  ? 598 HOH D O   1 
HETATM 26165 O O   . HOH L 2 .   ? 52.857  23.684  0.424   1.00 44.86  ? 599 HOH D O   1 
HETATM 26166 O O   . HOH L 2 .   ? 24.437  25.971  -0.572  1.00 39.52  ? 600 HOH D O   1 
HETATM 26167 O O   . HOH L 2 .   ? 48.492  16.973  -17.507 1.00 45.88  ? 601 HOH D O   1 
HETATM 26168 O O   . HOH L 2 .   ? 14.394  29.888  11.114  1.00 34.14  ? 602 HOH D O   1 
HETATM 26169 O O   . HOH L 2 .   ? 31.608  46.195  0.137   1.00 31.99  ? 603 HOH D O   1 
HETATM 26170 O O   . HOH L 2 .   ? 43.690  1.161   -3.955  1.00 30.01  ? 604 HOH D O   1 
HETATM 26171 O O   . HOH L 2 .   ? 25.743  39.229  17.402  1.00 27.10  ? 605 HOH D O   1 
HETATM 26172 O O   . HOH L 2 .   ? 35.400  28.769  26.389  1.00 50.55  ? 606 HOH D O   1 
HETATM 26173 O O   . HOH L 2 .   ? 16.893  24.596  9.265   1.00 36.22  ? 607 HOH D O   1 
HETATM 26174 O O   . HOH L 2 .   ? 15.613  7.785   3.145   1.00 44.83  ? 608 HOH D O   1 
HETATM 26175 O O   . HOH L 2 .   ? 16.260  21.000  28.286  1.00 44.61  ? 609 HOH D O   1 
HETATM 26176 O O   . HOH L 2 .   ? 28.105  38.709  16.963  1.00 35.18  ? 610 HOH D O   1 
HETATM 26177 O O   . HOH L 2 .   ? 32.963  -4.907  -3.774  1.00 27.81  ? 611 HOH D O   1 
HETATM 26178 O O   . HOH L 2 .   ? 42.712  26.154  1.778   1.00 26.90  ? 612 HOH D O   1 
HETATM 26179 O O   . HOH L 2 .   ? 41.599  26.451  -2.220  1.00 26.82  ? 613 HOH D O   1 
HETATM 26180 O O   . HOH L 2 .   ? 21.801  40.072  -19.243 1.00 31.43  ? 614 HOH D O   1 
HETATM 26181 O O   . HOH L 2 .   ? 23.823  27.173  -8.710  1.00 39.63  ? 615 HOH D O   1 
HETATM 26182 O O   . HOH L 2 .   ? 17.589  29.491  4.833   1.00 49.76  ? 616 HOH D O   1 
HETATM 26183 O O   . HOH L 2 .   ? 54.442  13.751  -5.285  1.00 57.30  ? 617 HOH D O   1 
HETATM 26184 O O   . HOH L 2 .   ? 34.136  31.614  13.087  1.00 35.15  ? 618 HOH D O   1 
HETATM 26185 O O   . HOH L 2 .   ? 42.670  17.135  12.913  1.00 37.51  ? 619 HOH D O   1 
HETATM 26186 O O   . HOH L 2 .   ? 36.372  32.925  13.350  1.00 33.12  ? 620 HOH D O   1 
HETATM 26187 O O   . HOH L 2 .   ? 23.734  32.846  -24.663 1.00 43.01  ? 621 HOH D O   1 
HETATM 26188 O O   . HOH L 2 .   ? 40.802  36.057  1.344   1.00 22.22  ? 622 HOH D O   1 
HETATM 26189 O O   . HOH L 2 .   ? 43.475  27.247  5.093   1.00 38.11  ? 623 HOH D O   1 
HETATM 26190 O O   . HOH L 2 .   ? 26.159  24.180  -3.643  1.00 39.53  ? 624 HOH D O   1 
HETATM 26191 O O   . HOH L 2 .   ? 20.283  34.286  -4.035  1.00 46.45  ? 625 HOH D O   1 
HETATM 26192 O O   . HOH L 2 .   ? 39.758  39.114  -4.636  1.00 42.68  ? 626 HOH D O   1 
HETATM 26193 O O   . HOH L 2 .   ? 40.207  26.687  -4.733  1.00 25.73  ? 627 HOH D O   1 
HETATM 26194 O O   . HOH L 2 .   ? 30.813  48.087  -8.223  1.00 34.65  ? 628 HOH D O   1 
HETATM 26195 O O   . HOH L 2 .   ? 38.232  30.166  7.928   1.00 29.95  ? 629 HOH D O   1 
HETATM 26196 O O   . HOH L 2 .   ? 32.261  14.494  -12.704 1.00 45.43  ? 630 HOH D O   1 
HETATM 26197 O O   . HOH L 2 .   ? 17.364  46.267  -18.485 1.00 45.02  ? 631 HOH D O   1 
HETATM 26198 O O   . HOH L 2 .   ? 32.965  28.640  24.947  1.00 52.44  ? 632 HOH D O   1 
HETATM 26199 O O   . HOH L 2 .   ? 23.799  23.533  29.304  1.00 44.50  ? 633 HOH D O   1 
HETATM 26200 O O   . HOH L 2 .   ? 31.624  14.335  24.421  1.00 39.32  ? 634 HOH D O   1 
HETATM 26201 O O   . HOH L 2 .   ? 36.201  44.612  -0.759  1.00 39.33  ? 635 HOH D O   1 
HETATM 26202 O O   . HOH L 2 .   ? 34.151  13.431  23.709  1.00 51.17  ? 636 HOH D O   1 
HETATM 26203 O O   . HOH L 2 .   ? 43.580  1.028   3.531   1.00 43.45  ? 637 HOH D O   1 
HETATM 26204 O O   . HOH L 2 .   ? 10.046  29.649  16.531  1.00 43.80  ? 638 HOH D O   1 
HETATM 26205 O O   . HOH L 2 .   ? 44.395  2.334   1.904   1.00 35.86  ? 639 HOH D O   1 
HETATM 26206 O O   . HOH L 2 .   ? 34.580  25.372  32.962  1.00 39.99  ? 640 HOH D O   1 
HETATM 26207 O O   . HOH L 2 .   ? 9.816   18.027  14.307  1.00 44.00  ? 641 HOH D O   1 
HETATM 26208 O O   . HOH L 2 .   ? 16.644  40.002  20.430  1.00 35.69  ? 642 HOH D O   1 
HETATM 26209 O O   . HOH L 2 .   ? 18.217  27.712  4.364   1.00 39.74  ? 643 HOH D O   1 
HETATM 26210 O O   . HOH L 2 .   ? 22.637  13.049  -25.999 1.00 52.09  ? 644 HOH D O   1 
HETATM 26211 O O   . HOH L 2 .   ? 39.184  36.971  -3.373  1.00 27.04  ? 645 HOH D O   1 
HETATM 26212 O O   . HOH L 2 .   ? 39.482  37.830  -1.332  1.00 32.61  ? 646 HOH D O   1 
HETATM 26213 O O   . HOH L 2 .   ? 35.372  26.318  -16.788 1.00 43.30  ? 647 HOH D O   1 
HETATM 26214 O O   . HOH L 2 .   ? 13.807  6.673   8.858   1.00 43.09  ? 648 HOH D O   1 
HETATM 26215 O O   . HOH L 2 .   ? 43.968  18.210  15.647  1.00 44.78  ? 649 HOH D O   1 
HETATM 26216 O O   . HOH L 2 .   ? 32.410  26.495  34.622  1.00 36.61  ? 650 HOH D O   1 
HETATM 26217 O O   . HOH L 2 .   ? 15.738  1.852   17.436  1.00 43.86  ? 651 HOH D O   1 
HETATM 26218 O O   . HOH L 2 .   ? 22.830  15.237  -27.840 1.00 42.30  ? 652 HOH D O   1 
HETATM 26219 O O   . HOH L 2 .   ? 0.774   46.662  -7.194  1.00 49.68  ? 653 HOH D O   1 
HETATM 26220 O O   . HOH L 2 .   ? 46.185  2.872   4.682   1.00 52.52  ? 654 HOH D O   1 
HETATM 26221 O O   . HOH L 2 .   ? 12.108  6.727   3.870   1.00 51.51  ? 655 HOH D O   1 
HETATM 26222 O O   . HOH L 2 .   ? 34.921  33.888  18.681  1.00 48.98  ? 656 HOH D O   1 
HETATM 26223 O O   . HOH L 2 .   ? 5.861   20.603  12.895  1.00 41.69  ? 657 HOH D O   1 
HETATM 26224 O O   . HOH L 2 .   ? 6.635   17.036  13.729  1.00 44.38  ? 658 HOH D O   1 
HETATM 26225 O O   . HOH L 2 .   ? 37.006  35.065  19.304  1.00 43.76  ? 659 HOH D O   1 
HETATM 26226 O O   . HOH M 2 .   ? 73.389  -17.289 72.315  1.00 53.05  ? 501 HOH E O   1 
HETATM 26227 O O   . HOH M 2 .   ? 49.685  -50.080 64.102  1.00 44.32  ? 502 HOH E O   1 
HETATM 26228 O O   . HOH M 2 .   ? 61.409  -33.255 56.804  1.00 66.81  ? 503 HOH E O   1 
HETATM 26229 O O   . HOH M 2 .   ? 57.271  -11.814 76.286  1.00 40.31  ? 504 HOH E O   1 
HETATM 26230 O O   . HOH M 2 .   ? 65.471  -11.982 64.822  1.00 43.61  ? 505 HOH E O   1 
HETATM 26231 O O   . HOH M 2 .   ? 43.013  -18.362 57.731  1.00 45.07  ? 506 HOH E O   1 
HETATM 26232 O O   . HOH M 2 .   ? 63.405  -20.089 78.526  1.00 60.50  ? 507 HOH E O   1 
HETATM 26233 O O   . HOH M 2 .   ? 33.831  -20.227 65.580  1.00 42.26  ? 508 HOH E O   1 
HETATM 26234 O O   . HOH M 2 .   ? 39.656  -14.072 59.892  1.00 33.33  ? 509 HOH E O   1 
HETATM 26235 O O   . HOH M 2 .   ? 50.515  -37.749 51.324  1.00 47.79  ? 510 HOH E O   1 
HETATM 26236 O O   . HOH M 2 .   ? 51.016  -13.688 78.363  1.00 38.03  ? 511 HOH E O   1 
HETATM 26237 O O   . HOH M 2 .   ? 68.543  -24.396 84.112  1.00 56.93  ? 512 HOH E O   1 
HETATM 26238 O O   . HOH M 2 .   ? 81.074  -12.422 58.473  1.00 41.19  ? 513 HOH E O   1 
HETATM 26239 O O   . HOH M 2 .   ? 33.936  -37.038 62.688  1.00 37.07  ? 514 HOH E O   1 
HETATM 26240 O O   . HOH M 2 .   ? 59.957  -36.620 51.980  1.00 53.01  ? 515 HOH E O   1 
HETATM 26241 O O   . HOH M 2 .   ? 64.560  -32.966 76.393  1.00 56.20  ? 516 HOH E O   1 
HETATM 26242 O O   . HOH M 2 .   ? 41.431  -8.768  70.430  1.00 40.98  ? 517 HOH E O   1 
HETATM 26243 O O   . HOH M 2 .   ? 74.886  -13.593 65.716  1.00 40.20  ? 518 HOH E O   1 
HETATM 26244 O O   . HOH M 2 .   ? 63.736  -7.087  79.217  1.00 34.59  ? 519 HOH E O   1 
HETATM 26245 O O   . HOH M 2 .   ? 50.197  -45.968 68.350  1.00 34.59  ? 520 HOH E O   1 
HETATM 26246 O O   . HOH M 2 .   ? 46.012  -0.252  60.856  1.00 22.29  ? 521 HOH E O   1 
HETATM 26247 O O   . HOH M 2 .   ? 52.264  -42.423 68.895  1.00 28.73  ? 522 HOH E O   1 
HETATM 26248 O O   . HOH M 2 .   ? 29.573  -28.478 69.299  1.00 50.36  ? 523 HOH E O   1 
HETATM 26249 O O   . HOH M 2 .   ? 68.023  -13.583 71.338  1.00 40.16  ? 524 HOH E O   1 
HETATM 26250 O O   . HOH M 2 .   ? 44.571  1.859   50.910  1.00 47.80  ? 525 HOH E O   1 
HETATM 26251 O O   . HOH M 2 .   ? 54.180  -0.170  89.753  1.00 41.85  ? 526 HOH E O   1 
HETATM 26252 O O   . HOH M 2 .   ? 66.749  -38.832 55.666  1.00 42.18  ? 527 HOH E O   1 
HETATM 26253 O O   . HOH M 2 .   ? 74.710  3.380   74.721  1.00 34.37  ? 528 HOH E O   1 
HETATM 26254 O O   . HOH M 2 .   ? 66.446  -14.650 51.329  1.00 36.23  ? 529 HOH E O   1 
HETATM 26255 O O   . HOH M 2 .   ? 50.558  3.137   58.585  1.00 38.66  ? 530 HOH E O   1 
HETATM 26256 O O   . HOH M 2 .   ? 37.135  -26.334 70.024  1.00 34.26  ? 531 HOH E O   1 
HETATM 26257 O O   . HOH M 2 .   ? 71.045  -6.811  56.232  1.00 42.63  ? 532 HOH E O   1 
HETATM 26258 O O   . HOH M 2 .   ? 64.429  -0.373  46.685  1.00 24.37  ? 533 HOH E O   1 
HETATM 26259 O O   . HOH M 2 .   ? 64.039  -1.792  43.345  1.00 43.38  ? 534 HOH E O   1 
HETATM 26260 O O   . HOH M 2 .   ? 46.704  -4.246  68.905  1.00 23.60  ? 535 HOH E O   1 
HETATM 26261 O O   . HOH M 2 .   ? 44.075  -1.795  69.494  1.00 35.43  ? 536 HOH E O   1 
HETATM 26262 O O   . HOH M 2 .   ? 83.579  -7.157  69.861  1.00 37.89  ? 537 HOH E O   1 
HETATM 26263 O O   . HOH M 2 .   ? 66.430  -30.404 43.693  1.00 47.22  ? 538 HOH E O   1 
HETATM 26264 O O   . HOH M 2 .   ? 56.687  -17.901 36.022  1.00 37.82  ? 539 HOH E O   1 
HETATM 26265 O O   . HOH M 2 .   ? 74.618  -8.896  69.155  1.00 29.48  ? 540 HOH E O   1 
HETATM 26266 O O   . HOH M 2 .   ? 62.188  -0.822  41.285  1.00 41.28  ? 541 HOH E O   1 
HETATM 26267 O O   . HOH M 2 .   ? 53.943  -12.549 45.414  1.00 27.53  ? 542 HOH E O   1 
HETATM 26268 O O   . HOH M 2 .   ? 63.226  -4.347  74.725  1.00 30.24  ? 543 HOH E O   1 
HETATM 26269 O O   . HOH M 2 .   ? 53.373  2.656   71.380  1.00 26.71  ? 544 HOH E O   1 
HETATM 26270 O O   . HOH M 2 .   ? 61.687  -25.650 72.261  1.00 47.33  ? 545 HOH E O   1 
HETATM 26271 O O   . HOH M 2 .   ? 67.079  -5.282  87.885  1.00 31.63  ? 546 HOH E O   1 
HETATM 26272 O O   . HOH M 2 .   ? 61.003  -41.640 67.755  1.00 33.27  ? 547 HOH E O   1 
HETATM 26273 O O   . HOH M 2 .   ? 54.611  -12.474 63.049  1.00 24.75  ? 548 HOH E O   1 
HETATM 26274 O O   . HOH M 2 .   ? 45.850  -0.152  49.801  1.00 45.70  ? 549 HOH E O   1 
HETATM 26275 O O   . HOH M 2 .   ? 57.087  -28.528 63.346  1.00 27.55  ? 550 HOH E O   1 
HETATM 26276 O O   . HOH M 2 .   ? 53.198  -43.497 59.545  1.00 36.72  ? 551 HOH E O   1 
HETATM 26277 O O   . HOH M 2 .   ? 58.686  4.301   76.234  1.00 26.06  ? 552 HOH E O   1 
HETATM 26278 O O   . HOH M 2 .   ? 44.168  -35.136 63.572  1.00 21.65  ? 553 HOH E O   1 
HETATM 26279 O O   . HOH M 2 .   ? 50.989  -38.841 80.590  1.00 57.30  ? 554 HOH E O   1 
HETATM 26280 O O   . HOH M 2 .   ? 63.547  -9.290  93.275  1.00 36.33  ? 555 HOH E O   1 
HETATM 26281 O O   . HOH M 2 .   ? 39.087  -15.190 66.242  1.00 23.98  ? 556 HOH E O   1 
HETATM 26282 O O   . HOH M 2 .   ? 55.163  0.144   81.714  1.00 32.57  ? 557 HOH E O   1 
HETATM 26283 O O   . HOH M 2 .   ? 56.300  -9.288  39.640  1.00 34.61  ? 558 HOH E O   1 
HETATM 26284 O O   . HOH M 2 .   ? 38.375  -31.819 59.462  1.00 44.55  ? 559 HOH E O   1 
HETATM 26285 O O   . HOH M 2 .   ? 54.616  -41.089 70.159  1.00 32.16  ? 560 HOH E O   1 
HETATM 26286 O O   . HOH M 2 .   ? 58.024  -10.570 69.014  1.00 29.21  ? 561 HOH E O   1 
HETATM 26287 O O   . HOH M 2 .   ? 56.212  -29.680 61.166  1.00 31.29  ? 562 HOH E O   1 
HETATM 26288 O O   . HOH M 2 .   ? 73.477  -12.196 96.439  1.00 38.76  ? 563 HOH E O   1 
HETATM 26289 O O   . HOH M 2 .   ? 43.391  -14.380 60.247  1.00 35.83  ? 564 HOH E O   1 
HETATM 26290 O O   . HOH M 2 .   ? 68.108  -0.466  88.186  1.00 34.49  ? 565 HOH E O   1 
HETATM 26291 O O   . HOH M 2 .   ? 43.590  -21.909 45.657  1.00 38.10  ? 566 HOH E O   1 
HETATM 26292 O O   . HOH M 2 .   ? 47.832  -15.264 45.441  1.00 40.25  ? 567 HOH E O   1 
HETATM 26293 O O   . HOH M 2 .   ? 64.806  -25.075 63.468  1.00 42.31  ? 568 HOH E O   1 
HETATM 26294 O O   . HOH M 2 .   ? 50.915  -7.412  52.905  1.00 23.12  ? 569 HOH E O   1 
HETATM 26295 O O   . HOH M 2 .   ? 65.801  -14.569 44.298  1.00 34.68  ? 570 HOH E O   1 
HETATM 26296 O O   . HOH M 2 .   ? 53.829  -20.248 61.945  1.00 20.62  ? 571 HOH E O   1 
HETATM 26297 O O   . HOH M 2 .   ? 71.538  2.672   74.991  1.00 25.03  ? 572 HOH E O   1 
HETATM 26298 O O   . HOH M 2 .   ? 70.904  -5.340  52.863  1.00 27.43  ? 573 HOH E O   1 
HETATM 26299 O O   . HOH M 2 .   ? 48.222  -13.812 78.555  1.00 34.17  ? 574 HOH E O   1 
HETATM 26300 O O   . HOH M 2 .   ? 61.247  -4.021  76.960  1.00 30.65  ? 575 HOH E O   1 
HETATM 26301 O O   . HOH M 2 .   ? 64.553  -7.559  41.221  1.00 41.23  ? 576 HOH E O   1 
HETATM 26302 O O   . HOH M 2 .   ? 33.199  -22.362 67.776  1.00 38.07  ? 577 HOH E O   1 
HETATM 26303 O O   . HOH M 2 .   ? 81.912  -13.210 63.643  1.00 39.93  ? 578 HOH E O   1 
HETATM 26304 O O   . HOH M 2 .   ? 73.107  -14.707 44.312  1.00 41.24  ? 579 HOH E O   1 
HETATM 26305 O O   . HOH M 2 .   ? 57.210  -17.646 67.411  1.00 40.14  ? 580 HOH E O   1 
HETATM 26306 O O   . HOH M 2 .   ? 51.550  -24.987 74.681  1.00 35.12  ? 581 HOH E O   1 
HETATM 26307 O O   . HOH M 2 .   ? 69.229  -0.633  65.436  1.00 25.74  ? 582 HOH E O   1 
HETATM 26308 O O   . HOH M 2 .   ? 42.166  -0.005  49.302  1.00 41.58  ? 583 HOH E O   1 
HETATM 26309 O O   . HOH M 2 .   ? 82.207  -0.514  75.890  1.00 60.21  ? 584 HOH E O   1 
HETATM 26310 O O   . HOH M 2 .   ? 51.522  -1.912  50.196  1.00 36.17  ? 585 HOH E O   1 
HETATM 26311 O O   . HOH M 2 .   ? 67.164  -31.983 54.614  1.00 45.52  ? 586 HOH E O   1 
HETATM 26312 O O   . HOH M 2 .   ? 48.169  -0.886  64.086  1.00 24.09  ? 587 HOH E O   1 
HETATM 26313 O O   . HOH M 2 .   ? 53.509  -43.706 56.970  1.00 43.29  ? 588 HOH E O   1 
HETATM 26314 O O   . HOH M 2 .   ? 59.287  -10.551 56.516  1.00 32.08  ? 589 HOH E O   1 
HETATM 26315 O O   . HOH M 2 .   ? 51.598  -11.257 37.342  1.00 39.04  ? 590 HOH E O   1 
HETATM 26316 O O   . HOH M 2 .   ? 50.942  -47.659 66.033  1.00 34.68  ? 591 HOH E O   1 
HETATM 26317 O O   . HOH M 2 .   ? 49.140  -4.044  49.867  1.00 30.23  ? 592 HOH E O   1 
HETATM 26318 O O   . HOH M 2 .   ? 63.854  -3.627  40.903  1.00 36.83  ? 593 HOH E O   1 
HETATM 26319 O O   . HOH M 2 .   ? 69.968  -3.875  49.341  1.00 23.14  ? 594 HOH E O   1 
HETATM 26320 O O   . HOH M 2 .   ? 31.897  -27.244 76.766  1.00 46.43  ? 595 HOH E O   1 
HETATM 26321 O O   . HOH M 2 .   ? 37.138  -22.919 79.837  1.00 37.16  ? 596 HOH E O   1 
HETATM 26322 O O   . HOH M 2 .   ? 71.323  -36.183 46.588  1.00 50.58  ? 597 HOH E O   1 
HETATM 26323 O O   . HOH M 2 .   ? 40.667  -14.810 62.586  1.00 31.00  ? 598 HOH E O   1 
HETATM 26324 O O   . HOH M 2 .   ? 46.171  -2.440  64.117  1.00 19.41  ? 599 HOH E O   1 
HETATM 26325 O O   . HOH M 2 .   ? 72.697  -11.586 47.409  1.00 37.05  ? 600 HOH E O   1 
HETATM 26326 O O   . HOH M 2 .   ? 71.190  -8.735  43.352  1.00 37.22  ? 601 HOH E O   1 
HETATM 26327 O O   . HOH M 2 .   ? 47.522  -39.447 52.998  1.00 31.94  ? 602 HOH E O   1 
HETATM 26328 O O   . HOH M 2 .   ? 65.810  -5.849  73.535  1.00 32.06  ? 603 HOH E O   1 
HETATM 26329 O O   . HOH M 2 .   ? 33.920  -19.052 68.812  1.00 36.63  ? 604 HOH E O   1 
HETATM 26330 O O   . HOH M 2 .   ? 82.101  -2.108  67.795  1.00 41.91  ? 605 HOH E O   1 
HETATM 26331 O O   . HOH M 2 .   ? 62.333  -1.360  83.802  1.00 31.70  ? 606 HOH E O   1 
HETATM 26332 O O   . HOH M 2 .   ? 53.416  -19.573 59.276  1.00 21.04  ? 607 HOH E O   1 
HETATM 26333 O O   . HOH M 2 .   ? 82.763  -9.067  68.830  1.00 30.63  ? 608 HOH E O   1 
HETATM 26334 O O   . HOH M 2 .   ? 42.877  -5.111  63.445  1.00 19.04  ? 609 HOH E O   1 
HETATM 26335 O O   . HOH M 2 .   ? 43.494  -16.845 69.221  1.00 30.48  ? 610 HOH E O   1 
HETATM 26336 O O   . HOH M 2 .   ? 49.499  -19.169 67.978  1.00 27.89  ? 611 HOH E O   1 
HETATM 26337 O O   . HOH M 2 .   ? 56.354  -0.292  51.346  1.00 24.51  ? 612 HOH E O   1 
HETATM 26338 O O   . HOH M 2 .   ? 34.919  -21.262 76.458  1.00 46.04  ? 613 HOH E O   1 
HETATM 26339 O O   . HOH M 2 .   ? 54.431  2.872   54.126  1.00 28.34  ? 614 HOH E O   1 
HETATM 26340 O O   . HOH M 2 .   ? 46.952  -3.133  83.599  1.00 43.25  ? 615 HOH E O   1 
HETATM 26341 O O   . HOH M 2 .   ? 38.250  -18.533 74.239  1.00 37.75  ? 616 HOH E O   1 
HETATM 26342 O O   . HOH M 2 .   ? 49.965  0.753   78.762  1.00 39.86  ? 617 HOH E O   1 
HETATM 26343 O O   . HOH M 2 .   ? 53.683  -14.835 54.137  1.00 35.83  ? 618 HOH E O   1 
HETATM 26344 O O   . HOH M 2 .   ? 49.160  -25.863 40.495  1.00 37.85  ? 619 HOH E O   1 
HETATM 26345 O O   . HOH M 2 .   ? 60.826  -11.499 73.956  1.00 45.24  ? 620 HOH E O   1 
HETATM 26346 O O   . HOH M 2 .   ? 50.245  2.878   55.616  1.00 40.50  ? 621 HOH E O   1 
HETATM 26347 O O   . HOH M 2 .   ? 42.372  -34.613 49.028  1.00 49.71  ? 622 HOH E O   1 
HETATM 26348 O O   . HOH M 2 .   ? 42.192  -14.516 67.200  1.00 19.59  ? 623 HOH E O   1 
HETATM 26349 O O   . HOH M 2 .   ? 64.899  -17.251 72.685  1.00 47.54  ? 624 HOH E O   1 
HETATM 26350 O O   . HOH M 2 .   ? 50.705  -19.488 33.002  1.00 43.44  ? 625 HOH E O   1 
HETATM 26351 O O   . HOH M 2 .   ? 41.394  0.525   68.112  1.00 36.81  ? 626 HOH E O   1 
HETATM 26352 O O   . HOH M 2 .   ? 40.053  -23.735 54.270  1.00 36.73  ? 627 HOH E O   1 
HETATM 26353 O O   . HOH M 2 .   ? 72.721  -17.207 51.210  1.00 37.25  ? 628 HOH E O   1 
HETATM 26354 O O   . HOH M 2 .   ? 51.761  5.166   64.758  1.00 25.51  ? 629 HOH E O   1 
HETATM 26355 O O   . HOH M 2 .   ? 52.728  7.033   72.650  1.00 40.14  ? 630 HOH E O   1 
HETATM 26356 O O   . HOH M 2 .   ? 65.747  2.665   79.190  1.00 39.56  ? 631 HOH E O   1 
HETATM 26357 O O   . HOH M 2 .   ? 41.222  -10.492 62.300  1.00 29.90  ? 632 HOH E O   1 
HETATM 26358 O O   . HOH M 2 .   ? 70.279  -16.474 53.814  1.00 44.71  ? 633 HOH E O   1 
HETATM 26359 O O   . HOH M 2 .   ? 48.980  4.329   72.465  1.00 38.09  ? 634 HOH E O   1 
HETATM 26360 O O   . HOH M 2 .   ? 58.056  -8.186  41.440  1.00 39.94  ? 635 HOH E O   1 
HETATM 26361 O O   . HOH M 2 .   ? 54.471  -2.361  47.694  1.00 35.28  ? 636 HOH E O   1 
HETATM 26362 O O   . HOH M 2 .   ? 49.703  6.791   72.559  1.00 45.48  ? 637 HOH E O   1 
HETATM 26363 O O   . HOH M 2 .   ? 46.082  -17.664 58.135  1.00 32.07  ? 638 HOH E O   1 
HETATM 26364 O O   . HOH M 2 .   ? 46.385  -12.987 56.826  1.00 23.44  ? 639 HOH E O   1 
HETATM 26365 O O   . HOH M 2 .   ? 55.491  -12.313 56.495  1.00 26.81  ? 640 HOH E O   1 
HETATM 26366 O O   . HOH M 2 .   ? 67.809  -7.148  41.081  1.00 35.52  ? 641 HOH E O   1 
HETATM 26367 O O   . HOH M 2 .   ? 57.479  -1.193  46.927  1.00 27.05  ? 642 HOH E O   1 
HETATM 26368 O O   . HOH M 2 .   ? 50.596  -11.011 52.557  1.00 32.83  ? 643 HOH E O   1 
HETATM 26369 O O   . HOH M 2 .   ? 68.290  -2.838  44.246  1.00 20.02  ? 644 HOH E O   1 
HETATM 26370 O O   . HOH M 2 .   ? 52.344  5.708   62.330  1.00 32.99  ? 645 HOH E O   1 
HETATM 26371 O O   . HOH M 2 .   ? 64.556  -22.784 55.288  1.00 39.68  ? 646 HOH E O   1 
HETATM 26372 O O   . HOH M 2 .   ? 43.404  -14.466 69.593  1.00 24.51  ? 647 HOH E O   1 
HETATM 26373 O O   . HOH M 2 .   ? 41.223  -24.159 48.042  1.00 39.30  ? 648 HOH E O   1 
HETATM 26374 O O   . HOH M 2 .   ? 45.231  -19.883 52.999  1.00 40.34  ? 649 HOH E O   1 
HETATM 26375 O O   . HOH M 2 .   ? 46.752  -44.614 61.255  1.00 36.55  ? 650 HOH E O   1 
HETATM 26376 O O   . HOH M 2 .   ? 44.885  -11.049 56.425  1.00 35.05  ? 651 HOH E O   1 
HETATM 26377 O O   . HOH M 2 .   ? 63.463  -24.244 69.151  1.00 47.55  ? 652 HOH E O   1 
HETATM 26378 O O   . HOH M 2 .   ? 55.692  -43.151 57.368  1.00 46.10  ? 653 HOH E O   1 
HETATM 26379 O O   . HOH M 2 .   ? 73.027  1.891   64.490  1.00 31.99  ? 654 HOH E O   1 
HETATM 26380 O O   . HOH M 2 .   ? 41.558  -36.230 60.163  1.00 33.35  ? 655 HOH E O   1 
HETATM 26381 O O   . HOH M 2 .   ? 41.867  -11.842 76.563  1.00 37.29  ? 656 HOH E O   1 
HETATM 26382 O O   . HOH M 2 .   ? 52.303  3.087   54.792  1.00 45.44  ? 657 HOH E O   1 
HETATM 26383 O O   . HOH M 2 .   ? 39.607  -39.952 68.367  1.00 25.96  ? 658 HOH E O   1 
HETATM 26384 O O   . HOH M 2 .   ? 41.293  -12.258 63.590  1.00 30.48  ? 659 HOH E O   1 
HETATM 26385 O O   . HOH M 2 .   ? 72.546  -8.123  45.472  1.00 37.13  ? 660 HOH E O   1 
HETATM 26386 O O   . HOH M 2 .   ? 47.004  -18.941 55.189  1.00 36.96  ? 661 HOH E O   1 
HETATM 26387 O O   . HOH M 2 .   ? 84.552  -12.966 64.435  1.00 45.21  ? 662 HOH E O   1 
HETATM 26388 O O   . HOH M 2 .   ? 49.920  8.410   67.445  1.00 44.35  ? 663 HOH E O   1 
HETATM 26389 O O   . HOH M 2 .   ? 35.940  -18.369 75.988  1.00 39.56  ? 664 HOH E O   1 
HETATM 26390 O O   . HOH M 2 .   ? 68.390  4.407   79.260  1.00 34.10  ? 665 HOH E O   1 
HETATM 26391 O O   . HOH M 2 .   ? 81.417  1.442   75.699  1.00 54.68  ? 666 HOH E O   1 
HETATM 26392 O O   . HOH M 2 .   ? 64.210  -38.725 55.706  1.00 48.43  ? 667 HOH E O   1 
HETATM 26393 O O   . HOH M 2 .   ? 52.113  7.589   66.320  1.00 35.09  ? 668 HOH E O   1 
HETATM 26394 O O   . HOH M 2 .   ? 34.827  -21.774 78.275  1.00 55.69  ? 669 HOH E O   1 
HETATM 26395 O O   . HOH M 2 .   ? 63.147  -41.999 61.085  1.00 36.92  ? 670 HOH E O   1 
HETATM 26396 O O   . HOH M 2 .   ? 40.730  -0.634  53.123  1.00 41.58  ? 671 HOH E O   1 
HETATM 26397 O O   . HOH M 2 .   ? 72.251  -18.645 55.541  1.00 46.33  ? 672 HOH E O   1 
HETATM 26398 O O   . HOH M 2 .   ? 65.755  -41.572 60.399  1.00 43.67  ? 673 HOH E O   1 
HETATM 26399 O O   . HOH M 2 .   ? 55.672  -47.558 60.526  1.00 49.33  ? 674 HOH E O   1 
HETATM 26400 O O   . HOH M 2 .   ? 72.010  -16.131 55.966  1.00 44.56  ? 675 HOH E O   1 
HETATM 26401 O O   . HOH M 2 .   ? 52.977  9.867   72.524  1.00 46.66  ? 676 HOH E O   1 
HETATM 26402 O O   . HOH M 2 .   ? 51.758  -38.180 82.085  1.00 42.25  ? 677 HOH E O   1 
HETATM 26403 O O   . HOH M 2 .   ? 31.593  -25.346 75.983  1.00 44.18  ? 678 HOH E O   1 
HETATM 26404 O O   . HOH M 2 .   ? 47.142  -1.849  48.811  1.00 50.05  ? 679 HOH E O   1 
HETATM 26405 O O   . HOH M 2 .   ? 54.437  -0.682  49.372  1.00 31.84  ? 680 HOH E O   1 
HETATM 26406 O O   . HOH M 2 .   ? 46.725  -0.191  83.251  1.00 38.41  ? 681 HOH E O   1 
HETATM 26407 O O   . HOH M 2 .   ? 64.646  -33.071 81.444  1.00 49.64  ? 682 HOH E O   1 
HETATM 26408 O O   . HOH M 2 .   ? 43.972  -3.471  65.721  1.00 21.20  ? 683 HOH E O   1 
HETATM 26409 O O   . HOH M 2 .   ? 39.700  -18.917 56.321  1.00 40.83  ? 684 HOH E O   1 
HETATM 26410 O O   . HOH M 2 .   ? 48.008  -39.383 50.063  1.00 35.26  ? 685 HOH E O   1 
HETATM 26411 O O   . HOH M 2 .   ? 39.299  -17.016 55.818  1.00 39.75  ? 686 HOH E O   1 
HETATM 26412 O O   . HOH M 2 .   ? 43.944  -4.252  68.290  1.00 43.35  ? 687 HOH E O   1 
HETATM 26413 O O   . HOH M 2 .   ? 86.287  -8.427  70.702  1.00 49.05  ? 688 HOH E O   1 
HETATM 26414 O O   . HOH M 2 .   ? 53.416  -34.496 47.937  1.00 39.63  ? 689 HOH E O   1 
HETATM 26415 O O   . HOH M 2 .   ? 54.088  2.520   88.410  1.00 46.03  ? 690 HOH E O   1 
HETATM 26416 O O   . HOH M 2 .   ? 53.139  -12.252 53.101  1.00 34.39  ? 691 HOH E O   1 
HETATM 26417 O O   . HOH M 2 .   ? 61.116  -1.280  38.913  1.00 47.14  ? 692 HOH E O   1 
HETATM 26418 O O   . HOH M 2 .   ? 51.893  8.070   74.745  1.00 47.57  ? 693 HOH E O   1 
HETATM 26419 O O   . HOH M 2 .   ? 67.573  -40.977 53.775  1.00 37.88  ? 694 HOH E O   1 
HETATM 26420 O O   . HOH M 2 .   ? 41.596  -6.410  68.610  1.00 31.77  ? 695 HOH E O   1 
HETATM 26421 O O   . HOH M 2 .   ? 67.324  -42.458 55.441  1.00 32.85  ? 696 HOH E O   1 
HETATM 26422 O O   . HOH M 2 .   ? 27.149  -25.217 70.499  1.00 47.08  ? 697 HOH E O   1 
HETATM 26423 O O   . HOH M 2 .   ? 36.435  -24.298 48.667  1.00 42.16  ? 698 HOH E O   1 
HETATM 26424 O O   . HOH M 2 .   ? 37.388  -22.353 50.525  1.00 41.32  ? 699 HOH E O   1 
HETATM 26425 O O   . HOH M 2 .   ? 65.036  -41.184 50.879  1.00 55.22  ? 700 HOH E O   1 
HETATM 26426 O O   . HOH N 2 .   ? -24.802 32.997  58.082  1.00 28.16  ? 501 HOH F O   1 
HETATM 26427 O O   . HOH N 2 .   ? -28.367 32.980  56.906  1.00 35.91  ? 502 HOH F O   1 
HETATM 26428 O O   . HOH N 2 .   ? -0.681  27.534  55.216  1.00 31.68  ? 503 HOH F O   1 
HETATM 26429 O O   . HOH N 2 .   ? -6.473  -7.738  34.805  1.00 51.93  ? 504 HOH F O   1 
HETATM 26430 O O   . HOH N 2 .   ? -19.124 24.106  44.442  1.00 45.61  ? 505 HOH F O   1 
HETATM 26431 O O   . HOH N 2 .   ? 1.360   38.750  42.031  1.00 39.68  ? 506 HOH F O   1 
HETATM 26432 O O   . HOH N 2 .   ? 0.219   20.752  85.866  1.00 50.63  ? 507 HOH F O   1 
HETATM 26433 O O   . HOH N 2 .   ? -13.863 7.674   71.797  1.00 32.45  ? 508 HOH F O   1 
HETATM 26434 O O   . HOH N 2 .   ? -17.229 6.827   48.761  1.00 31.56  ? 509 HOH F O   1 
HETATM 26435 O O   . HOH N 2 .   ? -18.317 31.862  75.530  1.00 42.02  ? 510 HOH F O   1 
HETATM 26436 O O   . HOH N 2 .   ? -12.198 15.277  42.844  1.00 37.50  ? 511 HOH F O   1 
HETATM 26437 O O   . HOH N 2 .   ? -1.226  7.926   53.037  1.00 52.63  ? 512 HOH F O   1 
HETATM 26438 O O   . HOH N 2 .   ? -23.643 7.436   37.288  1.00 37.36  ? 513 HOH F O   1 
HETATM 26439 O O   . HOH N 2 .   ? 1.214   23.280  64.586  1.00 41.46  ? 514 HOH F O   1 
HETATM 26440 O O   . HOH N 2 .   ? -13.283 10.015  51.004  1.00 34.08  ? 515 HOH F O   1 
HETATM 26441 O O   . HOH N 2 .   ? 5.701   43.771  55.284  1.00 38.64  ? 516 HOH F O   1 
HETATM 26442 O O   . HOH N 2 .   ? -12.223 20.238  56.720  1.00 33.56  ? 517 HOH F O   1 
HETATM 26443 O O   . HOH N 2 .   ? -16.112 7.809   51.725  1.00 30.12  ? 518 HOH F O   1 
HETATM 26444 O O   . HOH N 2 .   ? -3.341  44.547  69.105  1.00 29.75  ? 519 HOH F O   1 
HETATM 26445 O O   . HOH N 2 .   ? 2.361   20.169  69.818  1.00 47.35  ? 520 HOH F O   1 
HETATM 26446 O O   . HOH N 2 .   ? -10.985 45.963  48.772  1.00 48.33  ? 521 HOH F O   1 
HETATM 26447 O O   . HOH N 2 .   ? -17.456 21.303  68.770  1.00 30.22  ? 522 HOH F O   1 
HETATM 26448 O O   . HOH N 2 .   ? -16.920 31.271  45.838  1.00 38.08  ? 523 HOH F O   1 
HETATM 26449 O O   . HOH N 2 .   ? -15.931 27.520  41.429  1.00 46.23  ? 524 HOH F O   1 
HETATM 26450 O O   . HOH N 2 .   ? -16.638 41.345  52.193  1.00 42.51  ? 525 HOH F O   1 
HETATM 26451 O O   . HOH N 2 .   ? -8.337  11.151  84.122  1.00 41.75  ? 526 HOH F O   1 
HETATM 26452 O O   . HOH N 2 .   ? 5.407   36.981  53.714  1.00 31.32  ? 527 HOH F O   1 
HETATM 26453 O O   . HOH N 2 .   ? 4.862   -3.045  45.248  1.00 35.59  ? 528 HOH F O   1 
HETATM 26454 O O   . HOH N 2 .   ? -2.080  10.120  36.029  1.00 35.67  ? 529 HOH F O   1 
HETATM 26455 O O   . HOH N 2 .   ? -16.283 -6.265  49.829  1.00 22.86  ? 530 HOH F O   1 
HETATM 26456 O O   . HOH N 2 .   ? -22.476 5.472   76.982  1.00 29.01  ? 531 HOH F O   1 
HETATM 26457 O O   . HOH N 2 .   ? -17.779 19.289  60.052  1.00 23.30  ? 532 HOH F O   1 
HETATM 26458 O O   . HOH N 2 .   ? -20.637 15.652  81.204  1.00 36.87  ? 533 HOH F O   1 
HETATM 26459 O O   . HOH N 2 .   ? -17.040 38.001  74.015  1.00 36.39  ? 534 HOH F O   1 
HETATM 26460 O O   . HOH N 2 .   ? -13.049 3.843   36.373  1.00 24.56  ? 535 HOH F O   1 
HETATM 26461 O O   . HOH N 2 .   ? -8.598  29.437  48.508  1.00 32.44  ? 536 HOH F O   1 
HETATM 26462 O O   . HOH N 2 .   ? -21.072 8.426   82.633  1.00 40.58  ? 537 HOH F O   1 
HETATM 26463 O O   . HOH N 2 .   ? -12.175 24.939  61.142  1.00 23.34  ? 538 HOH F O   1 
HETATM 26464 O O   . HOH N 2 .   ? -19.556 20.860  77.447  1.00 28.64  ? 539 HOH F O   1 
HETATM 26465 O O   . HOH N 2 .   ? -5.993  41.634  59.425  1.00 25.64  ? 540 HOH F O   1 
HETATM 26466 O O   . HOH N 2 .   ? 3.647   29.186  45.158  1.00 46.81  ? 541 HOH F O   1 
HETATM 26467 O O   . HOH N 2 .   ? -29.284 19.524  72.072  1.00 32.89  ? 542 HOH F O   1 
HETATM 26468 O O   . HOH N 2 .   ? -11.850 22.573  43.271  1.00 41.81  ? 543 HOH F O   1 
HETATM 26469 O O   . HOH N 2 .   ? 2.600   8.488   38.691  1.00 29.50  ? 544 HOH F O   1 
HETATM 26470 O O   . HOH N 2 .   ? -1.863  -9.525  45.432  1.00 40.34  ? 545 HOH F O   1 
HETATM 26471 O O   . HOH N 2 .   ? -5.475  -6.056  62.731  1.00 33.55  ? 546 HOH F O   1 
HETATM 26472 O O   . HOH N 2 .   ? -30.179 38.795  57.156  1.00 34.73  ? 547 HOH F O   1 
HETATM 26473 O O   . HOH N 2 .   ? 8.991   37.868  60.706  1.00 37.91  ? 548 HOH F O   1 
HETATM 26474 O O   . HOH N 2 .   ? -5.504  36.380  38.683  1.00 49.87  ? 549 HOH F O   1 
HETATM 26475 O O   . HOH N 2 .   ? -29.158 27.364  58.128  1.00 28.51  ? 550 HOH F O   1 
HETATM 26476 O O   . HOH N 2 .   ? -30.546 10.456  68.016  1.00 39.27  ? 551 HOH F O   1 
HETATM 26477 O O   . HOH N 2 .   ? -11.655 48.662  51.793  1.00 51.39  ? 552 HOH F O   1 
HETATM 26478 O O   . HOH N 2 .   ? -32.776 10.790  56.779  1.00 34.43  ? 553 HOH F O   1 
HETATM 26479 O O   . HOH N 2 .   ? -9.925  31.133  43.295  1.00 44.19  ? 554 HOH F O   1 
HETATM 26480 O O   . HOH N 2 .   ? -15.619 27.766  54.508  1.00 25.50  ? 555 HOH F O   1 
HETATM 26481 O O   . HOH N 2 .   ? -14.805 23.091  86.838  1.00 38.72  ? 556 HOH F O   1 
HETATM 26482 O O   . HOH N 2 .   ? -21.681 22.370  40.953  1.00 40.50  ? 557 HOH F O   1 
HETATM 26483 O O   . HOH N 2 .   ? -27.835 23.954  70.378  1.00 43.84  ? 558 HOH F O   1 
HETATM 26484 O O   . HOH N 2 .   ? -18.931 -11.148 52.936  1.00 34.55  ? 559 HOH F O   1 
HETATM 26485 O O   . HOH N 2 .   ? -7.374  1.781   56.385  1.00 26.82  ? 560 HOH F O   1 
HETATM 26486 O O   . HOH N 2 .   ? -21.829 43.226  56.201  1.00 33.44  ? 561 HOH F O   1 
HETATM 26487 O O   . HOH N 2 .   ? -25.320 41.036  47.446  1.00 44.34  ? 562 HOH F O   1 
HETATM 26488 O O   . HOH N 2 .   ? -4.602  16.290  33.516  1.00 46.81  ? 563 HOH F O   1 
HETATM 26489 O O   . HOH N 2 .   ? -13.735 55.131  59.020  1.00 47.57  ? 564 HOH F O   1 
HETATM 26490 O O   . HOH N 2 .   ? -25.030 19.784  69.905  1.00 23.36  ? 565 HOH F O   1 
HETATM 26491 O O   . HOH N 2 .   ? -20.545 31.915  63.797  1.00 27.30  ? 566 HOH F O   1 
HETATM 26492 O O   . HOH N 2 .   ? -15.259 -6.368  42.007  1.00 40.29  ? 567 HOH F O   1 
HETATM 26493 O O   . HOH N 2 .   ? -33.062 8.483   49.302  1.00 47.06  ? 568 HOH F O   1 
HETATM 26494 O O   . HOH N 2 .   ? -17.859 0.553   58.902  1.00 25.26  ? 569 HOH F O   1 
HETATM 26495 O O   . HOH N 2 .   ? -32.831 18.816  60.930  1.00 34.11  ? 570 HOH F O   1 
HETATM 26496 O O   . HOH N 2 .   ? -30.663 19.711  57.834  1.00 41.32  ? 571 HOH F O   1 
HETATM 26497 O O   . HOH N 2 .   ? -16.645 -10.334 55.407  1.00 31.07  ? 572 HOH F O   1 
HETATM 26498 O O   . HOH N 2 .   ? -8.048  10.298  54.474  1.00 45.44  ? 573 HOH F O   1 
HETATM 26499 O O   . HOH N 2 .   ? -18.589 -0.327  38.224  1.00 34.52  ? 574 HOH F O   1 
HETATM 26500 O O   . HOH N 2 .   ? 9.275   41.979  61.537  1.00 47.81  ? 575 HOH F O   1 
HETATM 26501 O O   . HOH N 2 .   ? -10.637 47.507  60.202  1.00 31.29  ? 576 HOH F O   1 
HETATM 26502 O O   . HOH N 2 .   ? -19.243 40.581  65.565  1.00 38.42  ? 577 HOH F O   1 
HETATM 26503 O O   . HOH N 2 .   ? -3.441  28.868  62.662  1.00 31.82  ? 578 HOH F O   1 
HETATM 26504 O O   . HOH N 2 .   ? -32.701 13.114  63.598  1.00 30.34  ? 579 HOH F O   1 
HETATM 26505 O O   . HOH N 2 .   ? -0.761  -2.610  38.448  1.00 34.04  ? 580 HOH F O   1 
HETATM 26506 O O   . HOH N 2 .   ? -32.957 21.717  49.344  1.00 35.84  ? 581 HOH F O   1 
HETATM 26507 O O   . HOH N 2 .   ? -10.070 -7.771  56.436  1.00 30.94  ? 582 HOH F O   1 
HETATM 26508 O O   . HOH N 2 .   ? -25.004 29.794  50.991  1.00 39.75  ? 583 HOH F O   1 
HETATM 26509 O O   . HOH N 2 .   ? 0.029   -8.928  38.562  1.00 39.00  ? 584 HOH F O   1 
HETATM 26510 O O   . HOH N 2 .   ? -2.532  28.432  48.724  1.00 38.46  ? 585 HOH F O   1 
HETATM 26511 O O   . HOH N 2 .   ? -1.377  23.533  80.700  1.00 43.75  ? 586 HOH F O   1 
HETATM 26512 O O   . HOH N 2 .   ? -4.349  47.666  53.505  1.00 32.23  ? 587 HOH F O   1 
HETATM 26513 O O   . HOH N 2 .   ? 0.966   51.144  53.965  1.00 30.19  ? 588 HOH F O   1 
HETATM 26514 O O   . HOH N 2 .   ? -28.431 2.519   47.117  1.00 31.43  ? 589 HOH F O   1 
HETATM 26515 O O   . HOH N 2 .   ? -18.889 8.239   46.438  1.00 30.90  ? 590 HOH F O   1 
HETATM 26516 O O   . HOH N 2 .   ? -15.022 10.284  41.952  1.00 31.11  ? 591 HOH F O   1 
HETATM 26517 O O   . HOH N 2 .   ? -3.035  50.327  53.141  1.00 29.94  ? 592 HOH F O   1 
HETATM 26518 O O   . HOH N 2 .   ? -16.982 1.751   37.572  1.00 40.39  ? 593 HOH F O   1 
HETATM 26519 O O   . HOH N 2 .   ? -11.014 13.224  80.392  1.00 37.35  ? 594 HOH F O   1 
HETATM 26520 O O   . HOH N 2 .   ? 1.626   47.454  59.713  1.00 30.93  ? 595 HOH F O   1 
HETATM 26521 O O   . HOH N 2 .   ? 1.247   -0.856  38.668  1.00 29.78  ? 596 HOH F O   1 
HETATM 26522 O O   . HOH N 2 .   ? 3.636   25.161  51.017  1.00 36.75  ? 597 HOH F O   1 
HETATM 26523 O O   . HOH N 2 .   ? -23.763 30.268  54.591  1.00 25.54  ? 598 HOH F O   1 
HETATM 26524 O O   . HOH N 2 .   ? -23.534 2.956   42.762  1.00 34.05  ? 599 HOH F O   1 
HETATM 26525 O O   . HOH N 2 .   ? -28.716 20.342  52.925  1.00 29.17  ? 600 HOH F O   1 
HETATM 26526 O O   . HOH N 2 .   ? -12.270 9.427   31.923  1.00 34.82  ? 601 HOH F O   1 
HETATM 26527 O O   . HOH N 2 .   ? -9.160  23.872  42.089  1.00 35.89  ? 602 HOH F O   1 
HETATM 26528 O O   . HOH N 2 .   ? -29.519 11.010  50.817  1.00 24.77  ? 603 HOH F O   1 
HETATM 26529 O O   . HOH N 2 .   ? -16.818 15.177  66.589  1.00 22.11  ? 604 HOH F O   1 
HETATM 26530 O O   . HOH N 2 .   ? -12.218 33.145  82.122  1.00 40.59  ? 605 HOH F O   1 
HETATM 26531 O O   . HOH N 2 .   ? -24.542 19.238  82.403  1.00 32.90  ? 606 HOH F O   1 
HETATM 26532 O O   . HOH N 2 .   ? -28.934 15.317  72.397  1.00 29.23  ? 607 HOH F O   1 
HETATM 26533 O O   . HOH N 2 .   ? -19.405 5.426   39.301  1.00 22.20  ? 608 HOH F O   1 
HETATM 26534 O O   . HOH N 2 .   ? 9.914   31.976  56.694  1.00 31.44  ? 609 HOH F O   1 
HETATM 26535 O O   . HOH N 2 .   ? -20.704 30.746  52.805  1.00 28.30  ? 610 HOH F O   1 
HETATM 26536 O O   . HOH N 2 .   ? -10.692 12.372  49.286  1.00 42.12  ? 611 HOH F O   1 
HETATM 26537 O O   . HOH N 2 .   ? -25.916 9.864   73.130  1.00 25.19  ? 612 HOH F O   1 
HETATM 26538 O O   . HOH N 2 .   ? -2.311  3.312   57.089  1.00 37.48  ? 613 HOH F O   1 
HETATM 26539 O O   . HOH N 2 .   ? -2.025  -3.374  31.591  1.00 33.71  ? 614 HOH F O   1 
HETATM 26540 O O   . HOH N 2 .   ? -5.172  16.832  50.352  1.00 46.32  ? 615 HOH F O   1 
HETATM 26541 O O   . HOH N 2 .   ? -29.572 13.976  43.460  1.00 34.04  ? 616 HOH F O   1 
HETATM 26542 O O   . HOH N 2 .   ? -16.813 9.390   70.212  1.00 29.67  ? 617 HOH F O   1 
HETATM 26543 O O   . HOH N 2 .   ? -2.740  -5.114  57.225  1.00 28.08  ? 618 HOH F O   1 
HETATM 26544 O O   . HOH N 2 .   ? -14.037 -6.736  44.179  1.00 27.28  ? 619 HOH F O   1 
HETATM 26545 O O   . HOH N 2 .   ? -27.409 11.294  71.059  1.00 30.86  ? 620 HOH F O   1 
HETATM 26546 O O   . HOH N 2 .   ? -7.038  44.184  62.590  1.00 33.07  ? 621 HOH F O   1 
HETATM 26547 O O   . HOH N 2 .   ? -7.698  44.209  60.482  1.00 33.38  ? 622 HOH F O   1 
HETATM 26548 O O   . HOH N 2 .   ? -30.849 23.915  57.841  1.00 29.88  ? 623 HOH F O   1 
HETATM 26549 O O   . HOH N 2 .   ? -23.736 20.001  87.692  1.00 42.97  ? 624 HOH F O   1 
HETATM 26550 O O   . HOH N 2 .   ? 8.070   44.524  57.318  1.00 42.66  ? 625 HOH F O   1 
HETATM 26551 O O   . HOH N 2 .   ? -7.332  3.623   58.051  1.00 31.24  ? 626 HOH F O   1 
HETATM 26552 O O   . HOH N 2 .   ? -22.279 29.111  52.362  1.00 21.91  ? 627 HOH F O   1 
HETATM 26553 O O   . HOH N 2 .   ? -25.757 5.899   43.934  1.00 33.60  ? 628 HOH F O   1 
HETATM 26554 O O   . HOH N 2 .   ? -25.979 39.527  61.599  1.00 34.66  ? 629 HOH F O   1 
HETATM 26555 O O   . HOH N 2 .   ? -11.027 7.802   77.131  1.00 47.73  ? 630 HOH F O   1 
HETATM 26556 O O   . HOH N 2 .   ? 8.385   25.050  64.847  1.00 33.13  ? 631 HOH F O   1 
HETATM 26557 O O   . HOH N 2 .   ? -24.137 33.166  55.063  1.00 20.95  ? 632 HOH F O   1 
HETATM 26558 O O   . HOH N 2 .   ? -11.234 -10.501 39.519  1.00 47.30  ? 633 HOH F O   1 
HETATM 26559 O O   . HOH N 2 .   ? -4.034  8.778   73.913  1.00 35.10  ? 634 HOH F O   1 
HETATM 26560 O O   . HOH N 2 .   ? -3.499  33.615  78.558  1.00 43.60  ? 635 HOH F O   1 
HETATM 26561 O O   . HOH N 2 .   ? 5.591   41.197  71.385  1.00 43.51  ? 636 HOH F O   1 
HETATM 26562 O O   . HOH N 2 .   ? -17.710 -4.052  59.862  1.00 38.28  ? 637 HOH F O   1 
HETATM 26563 O O   . HOH N 2 .   ? -14.178 11.238  34.440  1.00 36.02  ? 638 HOH F O   1 
HETATM 26564 O O   . HOH N 2 .   ? -13.105 25.249  63.560  1.00 25.99  ? 639 HOH F O   1 
HETATM 26565 O O   . HOH N 2 .   ? -7.384  -10.438 54.399  1.00 36.47  ? 640 HOH F O   1 
HETATM 26566 O O   . HOH N 2 .   ? 7.095   42.892  48.746  1.00 61.03  ? 641 HOH F O   1 
HETATM 26567 O O   . HOH N 2 .   ? 9.298   36.228  56.193  1.00 29.54  ? 642 HOH F O   1 
HETATM 26568 O O   . HOH N 2 .   ? -17.861 29.936  67.403  1.00 28.92  ? 643 HOH F O   1 
HETATM 26569 O O   . HOH N 2 .   ? -12.160 16.018  88.318  1.00 50.70  ? 644 HOH F O   1 
HETATM 26570 O O   . HOH N 2 .   ? -34.288 14.528  70.306  1.00 51.60  ? 645 HOH F O   1 
HETATM 26571 O O   . HOH N 2 .   ? -21.452 6.367   80.217  1.00 43.29  ? 646 HOH F O   1 
HETATM 26572 O O   . HOH N 2 .   ? -11.892 -5.574  34.036  1.00 49.70  ? 647 HOH F O   1 
HETATM 26573 O O   . HOH N 2 .   ? -3.996  4.464   58.365  1.00 50.88  ? 648 HOH F O   1 
HETATM 26574 O O   . HOH N 2 .   ? -18.644 50.976  60.217  1.00 44.28  ? 649 HOH F O   1 
HETATM 26575 O O   . HOH N 2 .   ? 0.104   28.194  79.333  1.00 46.77  ? 650 HOH F O   1 
HETATM 26576 O O   . HOH N 2 .   ? -24.040 29.548  62.273  1.00 32.06  ? 651 HOH F O   1 
HETATM 26577 O O   . HOH N 2 .   ? -18.042 19.058  66.953  1.00 34.89  ? 652 HOH F O   1 
HETATM 26578 O O   . HOH N 2 .   ? -5.772  4.067   68.603  1.00 49.09  ? 653 HOH F O   1 
HETATM 26579 O O   . HOH N 2 .   ? -16.684 10.747  34.548  1.00 38.18  ? 654 HOH F O   1 
HETATM 26580 O O   . HOH N 2 .   ? -25.109 6.518   35.075  1.00 44.56  ? 655 HOH F O   1 
HETATM 26581 O O   . HOH N 2 .   ? -31.703 31.121  65.573  1.00 30.89  ? 656 HOH F O   1 
HETATM 26582 O O   . HOH N 2 .   ? -33.774 10.003  59.415  1.00 31.98  ? 657 HOH F O   1 
HETATM 26583 O O   . HOH N 2 .   ? -25.584 22.643  70.789  1.00 38.83  ? 658 HOH F O   1 
HETATM 26584 O O   . HOH N 2 .   ? -33.361 23.871  49.775  1.00 38.04  ? 659 HOH F O   1 
HETATM 26585 O O   . HOH N 2 .   ? -22.467 20.788  70.188  1.00 34.33  ? 660 HOH F O   1 
HETATM 26586 O O   . HOH N 2 .   ? -36.457 22.609  65.426  1.00 31.07  ? 661 HOH F O   1 
HETATM 26587 O O   . HOH N 2 .   ? 0.070   15.059  34.706  1.00 38.24  ? 662 HOH F O   1 
HETATM 26588 O O   . HOH N 2 .   ? 6.376   0.385   39.426  1.00 32.94  ? 663 HOH F O   1 
HETATM 26589 O O   . HOH N 2 .   ? -19.295 -1.206  36.672  1.00 47.81  ? 664 HOH F O   1 
HETATM 26590 O O   . HOH N 2 .   ? 2.922   13.370  80.830  1.00 45.50  ? 665 HOH F O   1 
HETATM 26591 O O   . HOH N 2 .   ? 1.472   20.274  67.872  1.00 40.06  ? 666 HOH F O   1 
HETATM 26592 O O   . HOH N 2 .   ? -22.330 5.888   38.777  1.00 36.90  ? 667 HOH F O   1 
HETATM 26593 O O   . HOH N 2 .   ? 0.696   6.755   34.760  1.00 34.71  ? 668 HOH F O   1 
HETATM 26594 O O   . HOH N 2 .   ? -1.325  16.013  33.982  1.00 37.00  ? 669 HOH F O   1 
HETATM 26595 O O   . HOH N 2 .   ? -10.211 20.717  55.014  1.00 50.37  ? 670 HOH F O   1 
HETATM 26596 O O   . HOH N 2 .   ? -0.066  20.669  65.078  1.00 41.66  ? 671 HOH F O   1 
HETATM 26597 O O   . HOH N 2 .   ? -27.292 30.069  56.909  1.00 45.84  ? 672 HOH F O   1 
HETATM 26598 O O   . HOH N 2 .   ? 8.211   37.662  53.957  1.00 37.37  ? 673 HOH F O   1 
HETATM 26599 O O   . HOH N 2 .   ? -26.525 29.816  52.575  1.00 45.63  ? 674 HOH F O   1 
HETATM 26600 O O   . HOH N 2 .   ? -12.593 20.255  54.609  1.00 38.07  ? 675 HOH F O   1 
HETATM 26601 O O   . HOH N 2 .   ? 11.342  34.234  55.378  1.00 29.54  ? 676 HOH F O   1 
HETATM 26602 O O   . HOH N 2 .   ? -21.293 -1.406  43.425  1.00 36.75  ? 677 HOH F O   1 
HETATM 26603 O O   . HOH N 2 .   ? -0.918  20.393  33.216  1.00 46.58  ? 678 HOH F O   1 
HETATM 26604 O O   . HOH N 2 .   ? -23.139 22.817  76.411  1.00 35.74  ? 679 HOH F O   1 
HETATM 26605 O O   . HOH N 2 .   ? 0.959   -6.084  61.568  1.00 57.99  ? 680 HOH F O   1 
HETATM 26606 O O   . HOH N 2 .   ? 4.436   5.302   36.486  1.00 29.49  ? 681 HOH F O   1 
HETATM 26607 O O   . HOH N 2 .   ? -24.997 22.342  73.893  1.00 50.31  ? 682 HOH F O   1 
HETATM 26608 O O   . HOH N 2 .   ? -13.695 -13.625 53.660  1.00 56.92  ? 683 HOH F O   1 
HETATM 26609 O O   . HOH N 2 .   ? -1.519  18.804  30.632  1.00 50.02  ? 684 HOH F O   1 
HETATM 26610 O O   . HOH N 2 .   ? -0.394  16.581  32.335  1.00 41.21  ? 685 HOH F O   1 
HETATM 26611 O O   . HOH N 2 .   ? 7.060   11.325  43.137  1.00 49.50  ? 686 HOH F O   1 
HETATM 26612 O O   . HOH N 2 .   ? 3.670   6.456   35.049  1.00 47.29  ? 687 HOH F O   1 
HETATM 26613 O O   . HOH N 2 .   ? 5.079   15.194  81.469  1.00 52.92  ? 688 HOH F O   1 
HETATM 26614 O O   . HOH N 2 .   ? 0.653   17.712  33.707  1.00 46.63  ? 689 HOH F O   1 
HETATM 26615 O O   . HOH N 2 .   ? -12.153 -14.507 54.707  1.00 44.13  ? 690 HOH F O   1 
HETATM 26616 O O   . HOH O 2 .   ? 29.485  25.822  38.915  1.00 35.06  ? 501 HOH G O   1 
HETATM 26617 O O   . HOH O 2 .   ? 28.868  21.025  49.708  1.00 39.19  ? 502 HOH G O   1 
HETATM 26618 O O   . HOH O 2 .   ? 19.445  32.046  34.509  1.00 49.85  ? 503 HOH G O   1 
HETATM 26619 O O   . HOH O 2 .   ? 12.276  29.247  64.584  1.00 42.66  ? 504 HOH G O   1 
HETATM 26620 O O   . HOH O 2 .   ? 28.569  12.540  35.821  1.00 44.90  ? 505 HOH G O   1 
HETATM 26621 O O   . HOH O 2 .   ? 2.552   -5.032  59.074  1.00 32.69  ? 506 HOH G O   1 
HETATM 26622 O O   . HOH O 2 .   ? 12.047  7.482   49.292  1.00 48.22  ? 507 HOH G O   1 
HETATM 26623 O O   . HOH O 2 .   ? 24.060  18.953  83.314  1.00 42.42  ? 508 HOH G O   1 
HETATM 26624 O O   . HOH O 2 .   ? 19.208  20.130  69.906  1.00 45.82  ? 509 HOH G O   1 
HETATM 26625 O O   . HOH O 2 .   ? 28.116  4.956   87.872  1.00 41.48  ? 510 HOH G O   1 
HETATM 26626 O O   . HOH O 2 .   ? 2.197   -15.479 62.071  1.00 38.28  ? 511 HOH G O   1 
HETATM 26627 O O   . HOH O 2 .   ? 26.209  16.882  58.811  1.00 36.31  ? 512 HOH G O   1 
HETATM 26628 O O   . HOH O 2 .   ? 37.863  8.151   70.582  1.00 27.87  ? 513 HOH G O   1 
HETATM 26629 O O   . HOH O 2 .   ? 14.814  6.459   48.178  1.00 49.80  ? 514 HOH G O   1 
HETATM 26630 O O   . HOH O 2 .   ? 19.297  14.954  53.340  1.00 57.26  ? 515 HOH G O   1 
HETATM 26631 O O   . HOH O 2 .   ? 39.412  13.744  35.642  1.00 37.86  ? 516 HOH G O   1 
HETATM 26632 O O   . HOH O 2 .   ? 30.415  -10.900 74.199  1.00 36.26  ? 517 HOH G O   1 
HETATM 26633 O O   . HOH O 2 .   ? 28.244  34.115  50.939  1.00 27.42  ? 518 HOH G O   1 
HETATM 26634 O O   . HOH O 2 .   ? 6.849   -11.621 56.788  1.00 39.48  ? 519 HOH G O   1 
HETATM 26635 O O   . HOH O 2 .   ? 7.721   24.647  54.282  1.00 45.62  ? 520 HOH G O   1 
HETATM 26636 O O   . HOH O 2 .   ? 33.867  12.960  71.803  1.00 37.36  ? 521 HOH G O   1 
HETATM 26637 O O   . HOH O 2 .   ? 46.741  18.580  53.409  1.00 42.91  ? 522 HOH G O   1 
HETATM 26638 O O   . HOH O 2 .   ? 35.969  -1.962  62.557  1.00 38.73  ? 523 HOH G O   1 
HETATM 26639 O O   . HOH O 2 .   ? 28.380  -3.375  46.814  1.00 36.02  ? 524 HOH G O   1 
HETATM 26640 O O   . HOH O 2 .   ? 10.231  39.200  49.360  1.00 34.29  ? 525 HOH G O   1 
HETATM 26641 O O   . HOH O 2 .   ? 17.614  33.877  64.402  1.00 40.07  ? 526 HOH G O   1 
HETATM 26642 O O   . HOH O 2 .   ? 15.442  -0.876  64.472  1.00 30.75  ? 527 HOH G O   1 
HETATM 26643 O O   . HOH O 2 .   ? 26.480  24.764  72.869  1.00 32.84  ? 528 HOH G O   1 
HETATM 26644 O O   . HOH O 2 .   ? 28.363  -13.309 52.727  1.00 30.60  ? 529 HOH G O   1 
HETATM 26645 O O   . HOH O 2 .   ? 32.961  -2.586  45.197  1.00 37.54  ? 530 HOH G O   1 
HETATM 26646 O O   . HOH O 2 .   ? 9.217   -17.766 62.776  1.00 30.12  ? 531 HOH G O   1 
HETATM 26647 O O   . HOH O 2 .   ? 40.988  16.798  51.451  1.00 31.50  ? 532 HOH G O   1 
HETATM 26648 O O   . HOH O 2 .   ? 35.593  22.488  77.550  1.00 26.04  ? 533 HOH G O   1 
HETATM 26649 O O   . HOH O 2 .   ? 27.443  19.490  69.936  1.00 35.57  ? 534 HOH G O   1 
HETATM 26650 O O   . HOH O 2 .   ? 29.680  12.817  67.537  1.00 28.25  ? 535 HOH G O   1 
HETATM 26651 O O   . HOH O 2 .   ? 24.399  24.144  37.658  1.00 34.61  ? 536 HOH G O   1 
HETATM 26652 O O   . HOH O 2 .   ? 24.014  19.296  73.132  1.00 27.23  ? 537 HOH G O   1 
HETATM 26653 O O   . HOH O 2 .   ? 30.235  -1.873  67.947  1.00 28.65  ? 538 HOH G O   1 
HETATM 26654 O O   . HOH O 2 .   ? 23.184  27.441  60.168  1.00 35.40  ? 539 HOH G O   1 
HETATM 26655 O O   . HOH O 2 .   ? 18.003  -13.986 60.583  1.00 26.11  ? 540 HOH G O   1 
HETATM 26656 O O   . HOH O 2 .   ? 30.013  27.145  59.641  1.00 27.21  ? 541 HOH G O   1 
HETATM 26657 O O   . HOH O 2 .   ? 30.595  19.794  47.906  1.00 24.40  ? 542 HOH G O   1 
HETATM 26658 O O   . HOH O 2 .   ? 18.084  20.391  34.479  1.00 45.44  ? 543 HOH G O   1 
HETATM 26659 O O   . HOH O 2 .   ? 4.936   -15.840 51.261  1.00 45.29  ? 544 HOH G O   1 
HETATM 26660 O O   . HOH O 2 .   ? 30.194  8.141   60.939  1.00 22.24  ? 545 HOH G O   1 
HETATM 26661 O O   . HOH O 2 .   ? 20.013  36.446  59.096  1.00 39.56  ? 546 HOH G O   1 
HETATM 26662 O O   . HOH O 2 .   ? 8.538   2.896   53.162  1.00 38.31  ? 547 HOH G O   1 
HETATM 26663 O O   . HOH O 2 .   ? 19.889  26.076  57.845  1.00 31.94  ? 548 HOH G O   1 
HETATM 26664 O O   . HOH O 2 .   ? 6.669   -8.764  55.976  1.00 26.90  ? 549 HOH G O   1 
HETATM 26665 O O   . HOH O 2 .   ? 40.431  7.666   53.400  1.00 23.56  ? 550 HOH G O   1 
HETATM 26666 O O   . HOH O 2 .   ? 15.756  -16.525 70.219  1.00 31.36  ? 551 HOH G O   1 
HETATM 26667 O O   . HOH O 2 .   ? 25.624  8.975   89.795  1.00 48.90  ? 552 HOH G O   1 
HETATM 26668 O O   . HOH O 2 .   ? 20.293  4.808   44.278  1.00 39.42  ? 553 HOH G O   1 
HETATM 26669 O O   . HOH O 2 .   ? 8.526   27.925  55.329  1.00 36.75  ? 554 HOH G O   1 
HETATM 26670 O O   . HOH O 2 .   ? 15.926  -1.343  49.572  1.00 32.64  ? 555 HOH G O   1 
HETATM 26671 O O   . HOH O 2 .   ? 16.936  17.217  82.603  1.00 36.15  ? 556 HOH G O   1 
HETATM 26672 O O   . HOH O 2 .   ? 14.139  -23.479 57.740  1.00 46.38  ? 557 HOH G O   1 
HETATM 26673 O O   . HOH O 2 .   ? 27.930  -11.702 40.545  1.00 41.11  ? 558 HOH G O   1 
HETATM 26674 O O   . HOH O 2 .   ? 17.794  29.592  69.909  1.00 44.09  ? 559 HOH G O   1 
HETATM 26675 O O   . HOH O 2 .   ? 16.123  36.057  58.993  1.00 34.50  ? 560 HOH G O   1 
HETATM 26676 O O   . HOH O 2 .   ? 6.133   33.276  41.251  1.00 48.05  ? 561 HOH G O   1 
HETATM 26677 O O   . HOH O 2 .   ? 29.450  5.304   69.953  1.00 46.70  ? 562 HOH G O   1 
HETATM 26678 O O   . HOH O 2 .   ? 33.251  -7.213  47.851  1.00 31.62  ? 563 HOH G O   1 
HETATM 26679 O O   . HOH O 2 .   ? 27.233  11.064  48.451  1.00 33.17  ? 564 HOH G O   1 
HETATM 26680 O O   . HOH O 2 .   ? 24.273  14.242  81.682  1.00 29.22  ? 565 HOH G O   1 
HETATM 26681 O O   . HOH O 2 .   ? 16.139  19.515  72.421  1.00 41.97  ? 566 HOH G O   1 
HETATM 26682 O O   . HOH O 2 .   ? 22.628  -5.453  40.986  1.00 52.11  ? 567 HOH G O   1 
HETATM 26683 O O   . HOH O 2 .   ? 41.568  21.611  45.346  1.00 39.61  ? 568 HOH G O   1 
HETATM 26684 O O   . HOH O 2 .   ? 45.233  16.661  57.358  1.00 31.64  ? 569 HOH G O   1 
HETATM 26685 O O   . HOH O 2 .   ? 29.627  -11.559 67.758  1.00 37.42  ? 570 HOH G O   1 
HETATM 26686 O O   . HOH O 2 .   ? 19.243  -19.893 53.694  1.00 39.46  ? 571 HOH G O   1 
HETATM 26687 O O   . HOH O 2 .   ? 24.269  -4.535  84.724  1.00 43.15  ? 572 HOH G O   1 
HETATM 26688 O O   . HOH O 2 .   ? 29.785  37.176  40.879  1.00 42.59  ? 573 HOH G O   1 
HETATM 26689 O O   . HOH O 2 .   ? 41.867  11.852  72.730  1.00 29.08  ? 574 HOH G O   1 
HETATM 26690 O O   . HOH O 2 .   ? 22.634  22.567  69.985  1.00 45.99  ? 575 HOH G O   1 
HETATM 26691 O O   . HOH O 2 .   ? 43.727  20.714  46.308  1.00 34.25  ? 576 HOH G O   1 
HETATM 26692 O O   . HOH O 2 .   ? 16.477  -19.784 55.116  1.00 26.63  ? 577 HOH G O   1 
HETATM 26693 O O   . HOH O 2 .   ? 38.807  23.273  47.893  1.00 32.97  ? 578 HOH G O   1 
HETATM 26694 O O   . HOH O 2 .   ? 40.265  -3.791  51.294  1.00 46.28  ? 579 HOH G O   1 
HETATM 26695 O O   . HOH O 2 .   ? 38.380  12.229  78.046  1.00 36.46  ? 580 HOH G O   1 
HETATM 26696 O O   . HOH O 2 .   ? 40.302  24.978  47.883  1.00 29.91  ? 581 HOH G O   1 
HETATM 26697 O O   . HOH O 2 .   ? 31.282  30.788  45.463  1.00 29.41  ? 582 HOH G O   1 
HETATM 26698 O O   . HOH O 2 .   ? 29.018  24.604  75.966  1.00 31.02  ? 583 HOH G O   1 
HETATM 26699 O O   . HOH O 2 .   ? 35.369  3.282   84.234  1.00 43.50  ? 584 HOH G O   1 
HETATM 26700 O O   . HOH O 2 .   ? 25.565  2.669   65.382  1.00 24.01  ? 585 HOH G O   1 
HETATM 26701 O O   . HOH O 2 .   ? 2.963   -10.143 61.678  1.00 40.46  ? 586 HOH G O   1 
HETATM 26702 O O   . HOH O 2 .   ? 42.284  8.194   72.401  1.00 33.29  ? 587 HOH G O   1 
HETATM 26703 O O   . HOH O 2 .   ? 30.617  3.400   44.705  1.00 30.04  ? 588 HOH G O   1 
HETATM 26704 O O   . HOH O 2 .   ? 24.297  2.653   62.423  1.00 24.49  ? 589 HOH G O   1 
HETATM 26705 O O   . HOH O 2 .   ? 42.675  -10.051 52.900  1.00 36.93  ? 590 HOH G O   1 
HETATM 26706 O O   . HOH O 2 .   ? 10.455  -19.656 60.897  1.00 28.97  ? 591 HOH G O   1 
HETATM 26707 O O   . HOH O 2 .   ? 29.746  -10.648 42.454  1.00 39.07  ? 592 HOH G O   1 
HETATM 26708 O O   . HOH O 2 .   ? 31.215  22.626  40.668  1.00 31.30  ? 593 HOH G O   1 
HETATM 26709 O O   . HOH O 2 .   ? 16.976  -18.717 48.004  1.00 32.76  ? 594 HOH G O   1 
HETATM 26710 O O   . HOH O 2 .   ? 30.538  7.157   69.118  1.00 34.90  ? 595 HOH G O   1 
HETATM 26711 O O   . HOH O 2 .   ? 31.076  -4.744  76.114  1.00 32.27  ? 596 HOH G O   1 
HETATM 26712 O O   . HOH O 2 .   ? 11.400  7.986   64.585  1.00 42.39  ? 597 HOH G O   1 
HETATM 26713 O O   . HOH O 2 .   ? 13.754  -14.481 71.832  1.00 30.35  ? 598 HOH G O   1 
HETATM 26714 O O   . HOH O 2 .   ? 34.685  7.967   74.049  1.00 51.03  ? 599 HOH G O   1 
HETATM 26715 O O   . HOH O 2 .   ? 38.086  -11.526 61.747  1.00 29.14  ? 600 HOH G O   1 
HETATM 26716 O O   . HOH O 2 .   ? 18.997  -1.526  47.599  1.00 42.89  ? 601 HOH G O   1 
HETATM 26717 O O   . HOH O 2 .   ? 39.095  16.328  76.701  1.00 36.23  ? 602 HOH G O   1 
HETATM 26718 O O   . HOH O 2 .   ? 35.309  -2.643  55.398  1.00 24.10  ? 603 HOH G O   1 
HETATM 26719 O O   . HOH O 2 .   ? 27.206  0.238   55.636  1.00 26.79  ? 604 HOH G O   1 
HETATM 26720 O O   . HOH O 2 .   ? 7.039   -12.512 66.911  1.00 31.05  ? 605 HOH G O   1 
HETATM 26721 O O   . HOH O 2 .   ? 22.880  32.559  34.839  1.00 42.84  ? 606 HOH G O   1 
HETATM 26722 O O   . HOH O 2 .   ? 40.121  16.232  71.695  1.00 26.82  ? 607 HOH G O   1 
HETATM 26723 O O   . HOH O 2 .   ? 36.254  -5.336  55.313  1.00 21.15  ? 608 HOH G O   1 
HETATM 26724 O O   . HOH O 2 .   ? 21.819  -1.933  42.986  1.00 39.38  ? 609 HOH G O   1 
HETATM 26725 O O   . HOH O 2 .   ? 45.461  8.984   60.857  1.00 42.76  ? 610 HOH G O   1 
HETATM 26726 O O   . HOH O 2 .   ? 34.244  2.797   69.770  1.00 38.68  ? 611 HOH G O   1 
HETATM 26727 O O   . HOH O 2 .   ? 34.242  -1.191  53.021  1.00 26.08  ? 612 HOH G O   1 
HETATM 26728 O O   . HOH O 2 .   ? 26.761  4.626   42.998  1.00 42.01  ? 613 HOH G O   1 
HETATM 26729 O O   . HOH O 2 .   ? 34.916  21.578  81.288  1.00 40.60  ? 614 HOH G O   1 
HETATM 26730 O O   . HOH O 2 .   ? 26.520  17.612  43.332  1.00 33.46  ? 615 HOH G O   1 
HETATM 26731 O O   . HOH O 2 .   ? 19.516  -16.653 61.121  1.00 29.69  ? 616 HOH G O   1 
HETATM 26732 O O   . HOH O 2 .   ? 39.863  4.081   70.584  1.00 34.12  ? 617 HOH G O   1 
HETATM 26733 O O   . HOH O 2 .   ? 29.666  18.407  71.418  1.00 32.88  ? 618 HOH G O   1 
HETATM 26734 O O   . HOH O 2 .   ? 31.787  23.648  80.547  1.00 29.92  ? 619 HOH G O   1 
HETATM 26735 O O   . HOH O 2 .   ? 34.321  19.612  83.261  1.00 35.21  ? 620 HOH G O   1 
HETATM 26736 O O   . HOH O 2 .   ? 24.939  22.130  82.426  1.00 41.90  ? 621 HOH G O   1 
HETATM 26737 O O   . HOH O 2 .   ? 36.082  0.085   45.471  1.00 33.60  ? 622 HOH G O   1 
HETATM 26738 O O   . HOH O 2 .   ? 26.729  8.787   49.695  1.00 32.86  ? 623 HOH G O   1 
HETATM 26739 O O   . HOH O 2 .   ? 5.952   28.927  41.562  1.00 41.74  ? 624 HOH G O   1 
HETATM 26740 O O   . HOH O 2 .   ? 9.495   12.347  43.705  1.00 50.40  ? 625 HOH G O   1 
HETATM 26741 O O   . HOH O 2 .   ? 31.675  -1.376  65.230  1.00 30.37  ? 626 HOH G O   1 
HETATM 26742 O O   . HOH O 2 .   ? 25.997  -4.338  86.593  1.00 50.02  ? 627 HOH G O   1 
HETATM 26743 O O   . HOH O 2 .   ? 17.176  -3.063  45.548  1.00 41.61  ? 628 HOH G O   1 
HETATM 26744 O O   . HOH O 2 .   ? 16.453  8.713   70.808  1.00 39.23  ? 629 HOH G O   1 
HETATM 26745 O O   . HOH O 2 .   ? 34.513  -8.997  46.535  1.00 30.71  ? 630 HOH G O   1 
HETATM 26746 O O   . HOH O 2 .   ? 27.380  36.641  46.838  1.00 35.89  ? 631 HOH G O   1 
HETATM 26747 O O   . HOH O 2 .   ? 48.069  9.154   62.863  1.00 39.43  ? 632 HOH G O   1 
HETATM 26748 O O   . HOH O 2 .   ? 31.842  -2.957  53.395  1.00 26.24  ? 633 HOH G O   1 
HETATM 26749 O O   . HOH O 2 .   ? 23.193  -20.212 51.599  1.00 43.87  ? 634 HOH G O   1 
HETATM 26750 O O   . HOH O 2 .   ? 46.581  22.037  52.176  1.00 41.79  ? 635 HOH G O   1 
HETATM 26751 O O   . HOH O 2 .   ? 4.133   -12.013 53.691  1.00 43.17  ? 636 HOH G O   1 
HETATM 26752 O O   . HOH O 2 .   ? 33.433  -5.950  79.455  1.00 39.50  ? 637 HOH G O   1 
HETATM 26753 O O   . HOH O 2 .   ? 12.086  34.602  52.662  1.00 31.84  ? 638 HOH G O   1 
HETATM 26754 O O   . HOH O 2 .   ? 21.841  16.498  53.961  1.00 39.44  ? 639 HOH G O   1 
HETATM 26755 O O   . HOH O 2 .   ? 21.436  -10.564 84.210  1.00 41.13  ? 640 HOH G O   1 
HETATM 26756 O O   . HOH O 2 .   ? 30.417  -15.492 39.911  1.00 42.30  ? 641 HOH G O   1 
HETATM 26757 O O   . HOH O 2 .   ? 46.646  3.328   68.011  1.00 49.25  ? 642 HOH G O   1 
HETATM 26758 O O   . HOH O 2 .   ? 31.699  -6.928  77.176  1.00 38.23  ? 643 HOH G O   1 
HETATM 26759 O O   . HOH O 2 .   ? 16.677  21.960  30.389  1.00 54.74  ? 644 HOH G O   1 
HETATM 26760 O O   . HOH O 2 .   ? 25.191  23.897  69.857  1.00 42.22  ? 645 HOH G O   1 
HETATM 26761 O O   . HOH O 2 .   ? 37.661  21.906  44.326  1.00 37.71  ? 646 HOH G O   1 
HETATM 26762 O O   . HOH O 2 .   ? 34.741  24.212  80.328  1.00 32.30  ? 647 HOH G O   1 
HETATM 26763 O O   . HOH O 2 .   ? 19.699  -11.406 40.403  1.00 55.27  ? 648 HOH G O   1 
HETATM 26764 O O   . HOH O 2 .   ? 14.480  38.608  47.292  1.00 42.59  ? 649 HOH G O   1 
HETATM 26765 O O   . HOH O 2 .   ? 13.535  27.217  65.663  1.00 49.14  ? 650 HOH G O   1 
HETATM 26766 O O   . HOH O 2 .   ? 36.286  4.647   85.255  1.00 46.07  ? 651 HOH G O   1 
HETATM 26767 O O   . HOH O 2 .   ? 21.051  -18.047 52.661  1.00 39.16  ? 652 HOH G O   1 
HETATM 26768 O O   . HOH O 2 .   ? 46.270  13.726  68.353  1.00 42.97  ? 653 HOH G O   1 
HETATM 26769 O O   . HOH O 2 .   ? 42.157  15.210  72.931  1.00 35.49  ? 654 HOH G O   1 
HETATM 26770 O O   . HOH O 2 .   ? 48.099  12.851  67.277  1.00 36.24  ? 655 HOH G O   1 
HETATM 26771 O O   . HOH O 2 .   ? 49.198  5.851   64.848  1.00 25.35  ? 656 HOH G O   1 
HETATM 26772 O O   . HOH O 2 .   ? 41.463  -11.296 51.262  1.00 40.64  ? 657 HOH G O   1 
HETATM 26773 O O   . HOH O 2 .   ? 37.806  4.999   71.611  1.00 34.88  ? 658 HOH G O   1 
HETATM 26774 O O   . HOH O 2 .   ? 3.532   2.446   46.272  1.00 42.96  ? 659 HOH G O   1 
HETATM 26775 O O   . HOH O 2 .   ? 21.341  -10.006 39.036  1.00 41.88  ? 660 HOH G O   1 
HETATM 26776 O O   . HOH O 2 .   ? 33.730  -0.536  63.801  1.00 41.85  ? 661 HOH G O   1 
HETATM 26777 O O   . HOH O 2 .   ? 49.704  11.826  64.989  1.00 41.69  ? 662 HOH G O   1 
HETATM 26778 O O   . HOH O 2 .   ? 34.713  6.800   70.761  1.00 44.49  ? 663 HOH G O   1 
HETATM 26779 O O   . HOH O 2 .   ? 3.645   -9.185  55.402  1.00 38.52  ? 664 HOH G O   1 
HETATM 26780 O O   . HOH O 2 .   ? 29.613  -23.590 52.793  1.00 39.57  ? 665 HOH G O   1 
HETATM 26781 O O   . HOH O 2 .   ? 6.547   2.680   43.960  1.00 35.72  ? 666 HOH G O   1 
HETATM 26782 O O   . HOH O 2 .   ? 45.906  17.983  59.552  1.00 28.07  ? 667 HOH G O   1 
HETATM 26783 O O   . HOH O 2 .   ? 48.717  6.472   62.937  1.00 35.70  ? 668 HOH G O   1 
HETATM 26784 O O   . HOH O 2 .   ? 46.545  24.344  51.162  1.00 40.32  ? 669 HOH G O   1 
HETATM 26785 O O   . HOH O 2 .   ? 49.468  8.914   73.465  1.00 41.43  ? 670 HOH G O   1 
HETATM 26786 O O   . HOH O 2 .   ? 8.201   29.894  33.455  1.00 57.00  ? 671 HOH G O   1 
HETATM 26787 O O   . HOH O 2 .   ? 32.449  6.656   71.762  1.00 46.89  ? 672 HOH G O   1 
HETATM 26788 O O   . HOH O 2 .   ? 38.452  -1.561  54.079  1.00 48.74  ? 673 HOH G O   1 
HETATM 26789 O O   . HOH O 2 .   ? 47.052  12.840  55.937  1.00 32.92  ? 674 HOH G O   1 
HETATM 26790 O O   . HOH O 2 .   ? 33.637  1.332   71.103  1.00 54.75  ? 675 HOH G O   1 
HETATM 26791 O O   . HOH O 2 .   ? 16.695  39.538  45.787  1.00 39.53  ? 676 HOH G O   1 
HETATM 26792 O O   . HOH O 2 .   ? 7.571   23.067  55.918  1.00 37.51  ? 677 HOH G O   1 
HETATM 26793 O O   . HOH O 2 .   ? 44.826  7.291   73.764  1.00 41.58  ? 678 HOH G O   1 
HETATM 26794 O O   . HOH O 2 .   ? 5.055   -16.385 49.271  1.00 44.84  ? 679 HOH G O   1 
HETATM 26795 O O   . HOH O 2 .   ? 47.153  14.682  56.879  1.00 36.22  ? 680 HOH G O   1 
HETATM 26796 O O   . HOH O 2 .   ? 17.108  -21.454 57.710  1.00 33.37  ? 681 HOH G O   1 
HETATM 26797 O O   . HOH O 2 .   ? 39.685  22.086  43.864  1.00 48.31  ? 682 HOH G O   1 
HETATM 26798 O O   . HOH O 2 .   ? 50.093  9.731   62.276  1.00 43.00  ? 683 HOH G O   1 
HETATM 26799 O O   . HOH O 2 .   ? 18.993  -11.845 85.549  1.00 47.63  ? 684 HOH G O   1 
HETATM 26800 O O   . HOH O 2 .   ? 13.015  15.390  60.612  1.00 42.98  ? 685 HOH G O   1 
HETATM 26801 O O   . HOH O 2 .   ? 8.936   29.253  31.187  1.00 56.14  ? 686 HOH G O   1 
HETATM 26802 O O   . HOH O 2 .   ? 31.569  -22.984 50.483  1.00 40.22  ? 687 HOH G O   1 
HETATM 26803 O O   . HOH O 2 .   ? 41.780  23.368  42.346  1.00 46.56  ? 688 HOH G O   1 
HETATM 26804 O O   . HOH O 2 .   ? 11.137  16.290  62.047  1.00 45.21  ? 689 HOH G O   1 
HETATM 26805 O O   . HOH O 2 .   ? 5.543   7.531   35.386  1.00 33.92  ? 690 HOH G O   1 
HETATM 26806 O O   . HOH O 2 .   ? 40.792  21.130  41.109  1.00 41.85  ? 691 HOH G O   1 
HETATM 26807 O O   . HOH P 2 .   ? 14.702  -42.583 48.711  1.00 50.18  ? 501 HOH H O   1 
HETATM 26808 O O   . HOH P 2 .   ? 22.063  -42.526 64.661  1.00 33.91  ? 502 HOH H O   1 
HETATM 26809 O O   . HOH P 2 .   ? -3.951  -59.093 77.375  1.00 29.19  ? 503 HOH H O   1 
HETATM 26810 O O   . HOH P 2 .   ? -10.648 -45.666 89.451  1.00 50.90  ? 504 HOH H O   1 
HETATM 26811 O O   . HOH P 2 .   ? -14.580 -39.190 53.510  1.00 36.59  ? 505 HOH H O   1 
HETATM 26812 O O   . HOH P 2 .   ? -16.974 -65.367 75.644  1.00 31.40  ? 506 HOH H O   1 
HETATM 26813 O O   . HOH P 2 .   ? 15.787  -48.002 62.785  1.00 44.30  ? 507 HOH H O   1 
HETATM 26814 O O   . HOH P 2 .   ? -6.525  -56.026 78.855  1.00 38.19  ? 508 HOH H O   1 
HETATM 26815 O O   . HOH P 2 .   ? -2.556  -61.268 89.781  1.00 42.05  ? 509 HOH H O   1 
HETATM 26816 O O   . HOH P 2 .   ? -11.505 -35.807 45.118  1.00 50.11  ? 510 HOH H O   1 
HETATM 26817 O O   . HOH P 2 .   ? 4.334   -20.194 69.955  1.00 35.20  ? 511 HOH H O   1 
HETATM 26818 O O   . HOH P 2 .   ? 15.417  -65.039 72.390  1.00 44.38  ? 512 HOH H O   1 
HETATM 26819 O O   . HOH P 2 .   ? -27.993 -48.850 89.592  1.00 44.71  ? 513 HOH H O   1 
HETATM 26820 O O   . HOH P 2 .   ? -21.356 -48.279 89.476  1.00 43.47  ? 514 HOH H O   1 
HETATM 26821 O O   . HOH P 2 .   ? 26.052  -46.302 66.886  1.00 41.48  ? 515 HOH H O   1 
HETATM 26822 O O   . HOH P 2 .   ? -8.360  -50.640 65.623  1.00 45.58  ? 516 HOH H O   1 
HETATM 26823 O O   . HOH P 2 .   ? -6.297  -37.502 81.365  1.00 54.50  ? 517 HOH H O   1 
HETATM 26824 O O   . HOH P 2 .   ? 10.308  -64.625 63.667  1.00 34.80  ? 518 HOH H O   1 
HETATM 26825 O O   . HOH P 2 .   ? 2.343   -17.736 63.651  1.00 45.43  ? 519 HOH H O   1 
HETATM 26826 O O   . HOH P 2 .   ? 19.410  -36.074 70.045  1.00 29.73  ? 520 HOH H O   1 
HETATM 26827 O O   . HOH P 2 .   ? 8.050   -49.543 38.261  1.00 44.39  ? 521 HOH H O   1 
HETATM 26828 O O   . HOH P 2 .   ? 9.099   -49.534 79.033  1.00 33.29  ? 522 HOH H O   1 
HETATM 26829 O O   . HOH P 2 .   ? 4.080   -60.663 50.371  1.00 24.59  ? 523 HOH H O   1 
HETATM 26830 O O   . HOH P 2 .   ? -9.639  -47.687 44.856  1.00 30.06  ? 524 HOH H O   1 
HETATM 26831 O O   . HOH P 2 .   ? -1.850  -57.575 89.098  1.00 37.75  ? 525 HOH H O   1 
HETATM 26832 O O   . HOH P 2 .   ? 15.452  -50.042 71.318  1.00 35.90  ? 526 HOH H O   1 
HETATM 26833 O O   . HOH P 2 .   ? -22.203 -66.267 82.254  1.00 51.93  ? 527 HOH H O   1 
HETATM 26834 O O   . HOH P 2 .   ? 1.919   -49.819 46.385  1.00 33.12  ? 528 HOH H O   1 
HETATM 26835 O O   . HOH P 2 .   ? -1.464  -25.793 60.535  1.00 43.16  ? 529 HOH H O   1 
HETATM 26836 O O   . HOH P 2 .   ? 9.673   -41.900 47.897  1.00 37.58  ? 530 HOH H O   1 
HETATM 26837 O O   . HOH P 2 .   ? -3.464  -42.891 93.978  1.00 58.28  ? 531 HOH H O   1 
HETATM 26838 O O   . HOH P 2 .   ? 18.230  -44.400 74.054  1.00 31.08  ? 532 HOH H O   1 
HETATM 26839 O O   . HOH P 2 .   ? 5.781   -37.749 75.390  1.00 38.44  ? 533 HOH H O   1 
HETATM 26840 O O   . HOH P 2 .   ? 3.895   -68.520 62.146  1.00 26.34  ? 534 HOH H O   1 
HETATM 26841 O O   . HOH P 2 .   ? 13.149  -45.894 69.701  1.00 26.40  ? 535 HOH H O   1 
HETATM 26842 O O   . HOH P 2 .   ? 3.082   -43.177 59.672  1.00 26.94  ? 536 HOH H O   1 
HETATM 26843 O O   . HOH P 2 .   ? -10.236 -51.731 64.578  1.00 41.94  ? 537 HOH H O   1 
HETATM 26844 O O   . HOH P 2 .   ? 12.962  -44.393 58.403  1.00 38.70  ? 538 HOH H O   1 
HETATM 26845 O O   . HOH P 2 .   ? 0.441   -53.917 52.264  1.00 27.79  ? 539 HOH H O   1 
HETATM 26846 O O   . HOH P 2 .   ? -16.135 -43.966 44.908  1.00 35.90  ? 540 HOH H O   1 
HETATM 26847 O O   . HOH P 2 .   ? 11.880  -25.178 51.488  1.00 31.17  ? 541 HOH H O   1 
HETATM 26848 O O   . HOH P 2 .   ? 11.138  -23.019 55.042  1.00 34.63  ? 542 HOH H O   1 
HETATM 26849 O O   . HOH P 2 .   ? 5.682   -24.789 52.198  1.00 34.98  ? 543 HOH H O   1 
HETATM 26850 O O   . HOH P 2 .   ? -8.455  -61.943 47.513  1.00 25.95  ? 544 HOH H O   1 
HETATM 26851 O O   . HOH P 2 .   ? 17.207  -36.238 56.062  1.00 31.06  ? 545 HOH H O   1 
HETATM 26852 O O   . HOH P 2 .   ? 1.860   -50.450 63.791  1.00 22.28  ? 546 HOH H O   1 
HETATM 26853 O O   . HOH P 2 .   ? 2.652   -42.651 62.914  1.00 22.07  ? 547 HOH H O   1 
HETATM 26854 O O   . HOH P 2 .   ? -1.181  -44.329 36.704  1.00 42.96  ? 548 HOH H O   1 
HETATM 26855 O O   . HOH P 2 .   ? -8.932  -41.967 88.484  1.00 48.14  ? 549 HOH H O   1 
HETATM 26856 O O   . HOH P 2 .   ? 2.323   -54.760 88.802  1.00 53.89  ? 550 HOH H O   1 
HETATM 26857 O O   . HOH P 2 .   ? 12.269  -27.612 64.295  1.00 24.69  ? 551 HOH H O   1 
HETATM 26858 O O   . HOH P 2 .   ? -6.652  -57.673 67.422  1.00 26.49  ? 552 HOH H O   1 
HETATM 26859 O O   . HOH P 2 .   ? -7.874  -49.374 71.000  1.00 47.60  ? 553 HOH H O   1 
HETATM 26860 O O   . HOH P 2 .   ? 8.152   -23.029 54.216  1.00 30.96  ? 554 HOH H O   1 
HETATM 26861 O O   . HOH P 2 .   ? 3.663   -65.339 71.955  1.00 23.97  ? 555 HOH H O   1 
HETATM 26862 O O   . HOH P 2 .   ? 5.425   -28.621 46.060  1.00 38.17  ? 556 HOH H O   1 
HETATM 26863 O O   . HOH P 2 .   ? 16.650  -48.922 59.454  1.00 41.36  ? 557 HOH H O   1 
HETATM 26864 O O   . HOH P 2 .   ? 11.900  -17.739 64.943  1.00 33.63  ? 558 HOH H O   1 
HETATM 26865 O O   . HOH P 2 .   ? -9.497  -57.509 88.875  1.00 32.78  ? 559 HOH H O   1 
HETATM 26866 O O   . HOH P 2 .   ? -28.071 -55.261 72.444  1.00 43.46  ? 560 HOH H O   1 
HETATM 26867 O O   . HOH P 2 .   ? 2.084   -48.115 54.788  1.00 29.27  ? 561 HOH H O   1 
HETATM 26868 O O   . HOH P 2 .   ? -13.593 -51.836 47.797  1.00 27.92  ? 562 HOH H O   1 
HETATM 26869 O O   . HOH P 2 .   ? -23.520 -61.548 70.415  1.00 34.59  ? 563 HOH H O   1 
HETATM 26870 O O   . HOH P 2 .   ? 10.614  -62.640 60.644  1.00 26.44  ? 564 HOH H O   1 
HETATM 26871 O O   . HOH P 2 .   ? -3.071  -54.174 89.687  1.00 35.58  ? 565 HOH H O   1 
HETATM 26872 O O   . HOH P 2 .   ? 8.218   -61.793 64.300  1.00 26.86  ? 566 HOH H O   1 
HETATM 26873 O O   . HOH P 2 .   ? 14.963  -52.201 62.439  1.00 24.10  ? 567 HOH H O   1 
HETATM 26874 O O   . HOH P 2 .   ? -3.007  -51.730 57.528  1.00 32.59  ? 568 HOH H O   1 
HETATM 26875 O O   . HOH P 2 .   ? 1.879   -22.080 71.420  1.00 30.53  ? 569 HOH H O   1 
HETATM 26876 O O   . HOH P 2 .   ? 11.936  -70.907 71.841  1.00 46.79  ? 570 HOH H O   1 
HETATM 26877 O O   . HOH P 2 .   ? -9.751  -46.398 53.992  1.00 31.37  ? 571 HOH H O   1 
HETATM 26878 O O   . HOH P 2 .   ? 5.015   -55.152 53.108  1.00 26.27  ? 572 HOH H O   1 
HETATM 26879 O O   . HOH P 2 .   ? -8.498  -41.037 90.431  1.00 50.18  ? 573 HOH H O   1 
HETATM 26880 O O   . HOH P 2 .   ? -0.395  -64.032 86.208  1.00 47.50  ? 574 HOH H O   1 
HETATM 26881 O O   . HOH P 2 .   ? -5.070  -62.030 84.501  1.00 30.47  ? 575 HOH H O   1 
HETATM 26882 O O   . HOH P 2 .   ? 17.238  -47.473 66.346  1.00 24.06  ? 576 HOH H O   1 
HETATM 26883 O O   . HOH P 2 .   ? 2.716   -19.388 60.750  1.00 41.82  ? 577 HOH H O   1 
HETATM 26884 O O   . HOH P 2 .   ? 3.806   -50.285 38.424  1.00 41.78  ? 578 HOH H O   1 
HETATM 26885 O O   . HOH P 2 .   ? 14.883  -49.904 63.785  1.00 26.80  ? 579 HOH H O   1 
HETATM 26886 O O   . HOH P 2 .   ? 19.831  -37.845 81.981  1.00 45.17  ? 580 HOH H O   1 
HETATM 26887 O O   . HOH P 2 .   ? -17.740 -53.557 69.791  1.00 36.89  ? 581 HOH H O   1 
HETATM 26888 O O   . HOH P 2 .   ? 4.607   -67.764 65.087  1.00 29.32  ? 582 HOH H O   1 
HETATM 26889 O O   . HOH P 2 .   ? 10.851  -23.430 81.665  1.00 50.84  ? 583 HOH H O   1 
HETATM 26890 O O   . HOH P 2 .   ? 3.244   -44.235 81.086  1.00 46.79  ? 584 HOH H O   1 
HETATM 26891 O O   . HOH P 2 .   ? 10.180  -58.717 69.203  1.00 26.43  ? 585 HOH H O   1 
HETATM 26892 O O   . HOH P 2 .   ? 11.398  -41.067 45.297  1.00 40.44  ? 586 HOH H O   1 
HETATM 26893 O O   . HOH P 2 .   ? 11.503  -42.282 43.551  1.00 43.45  ? 587 HOH H O   1 
HETATM 26894 O O   . HOH P 2 .   ? 8.609   -32.500 81.159  1.00 43.36  ? 588 HOH H O   1 
HETATM 26895 O O   . HOH P 2 .   ? -0.782  -73.135 69.014  1.00 34.59  ? 589 HOH H O   1 
HETATM 26896 O O   . HOH P 2 .   ? 13.337  -48.725 60.527  1.00 32.20  ? 590 HOH H O   1 
HETATM 26897 O O   . HOH P 2 .   ? 3.408   -54.710 41.002  1.00 38.92  ? 591 HOH H O   1 
HETATM 26898 O O   . HOH P 2 .   ? -14.118 -58.648 50.245  1.00 26.42  ? 592 HOH H O   1 
HETATM 26899 O O   . HOH P 2 .   ? -24.034 -62.718 86.579  1.00 33.22  ? 593 HOH H O   1 
HETATM 26900 O O   . HOH P 2 .   ? 10.060  -60.133 64.222  1.00 27.04  ? 594 HOH H O   1 
HETATM 26901 O O   . HOH P 2 .   ? 4.378   -70.295 66.804  1.00 36.62  ? 595 HOH H O   1 
HETATM 26902 O O   . HOH P 2 .   ? 0.967   -59.839 47.868  1.00 30.04  ? 596 HOH H O   1 
HETATM 26903 O O   . HOH P 2 .   ? -8.928  -62.779 86.942  1.00 35.84  ? 597 HOH H O   1 
HETATM 26904 O O   . HOH P 2 .   ? 16.090  -38.488 54.983  1.00 32.51  ? 598 HOH H O   1 
HETATM 26905 O O   . HOH P 2 .   ? -0.501  -18.097 65.435  1.00 35.68  ? 599 HOH H O   1 
HETATM 26906 O O   . HOH P 2 .   ? 5.843   -65.927 58.714  1.00 27.65  ? 600 HOH H O   1 
HETATM 26907 O O   . HOH P 2 .   ? 9.067   -43.437 55.718  1.00 29.59  ? 601 HOH H O   1 
HETATM 26908 O O   . HOH P 2 .   ? -13.854 -51.423 49.944  1.00 27.44  ? 602 HOH H O   1 
HETATM 26909 O O   . HOH P 2 .   ? 14.725  -27.039 62.989  1.00 29.02  ? 603 HOH H O   1 
HETATM 26910 O O   . HOH P 2 .   ? 7.247   -58.320 50.240  1.00 34.59  ? 604 HOH H O   1 
HETATM 26911 O O   . HOH P 2 .   ? 6.137   -17.078 69.351  1.00 30.98  ? 605 HOH H O   1 
HETATM 26912 O O   . HOH P 2 .   ? 9.830   -49.579 57.497  1.00 28.99  ? 606 HOH H O   1 
HETATM 26913 O O   . HOH P 2 .   ? 14.902  -48.452 67.161  1.00 24.24  ? 607 HOH H O   1 
HETATM 26914 O O   . HOH P 2 .   ? -26.307 -49.409 71.382  1.00 45.73  ? 608 HOH H O   1 
HETATM 26915 O O   . HOH P 2 .   ? 12.246  -63.900 58.486  1.00 33.07  ? 609 HOH H O   1 
HETATM 26916 O O   . HOH P 2 .   ? -12.425 -51.126 57.224  1.00 38.94  ? 610 HOH H O   1 
HETATM 26917 O O   . HOH P 2 .   ? 19.939  -40.234 80.040  1.00 40.19  ? 611 HOH H O   1 
HETATM 26918 O O   . HOH P 2 .   ? -1.403  -61.089 47.711  1.00 29.10  ? 612 HOH H O   1 
HETATM 26919 O O   . HOH P 2 .   ? -27.858 -53.309 89.187  1.00 36.27  ? 613 HOH H O   1 
HETATM 26920 O O   . HOH P 2 .   ? -3.467  -48.605 73.104  1.00 42.90  ? 614 HOH H O   1 
HETATM 26921 O O   . HOH P 2 .   ? -24.940 -62.305 91.416  1.00 51.42  ? 615 HOH H O   1 
HETATM 26922 O O   . HOH P 2 .   ? 13.359  -61.844 80.481  1.00 41.37  ? 616 HOH H O   1 
HETATM 26923 O O   . HOH P 2 .   ? 4.307   -18.443 77.397  1.00 49.81  ? 617 HOH H O   1 
HETATM 26924 O O   . HOH P 2 .   ? 6.050   -47.365 49.935  1.00 30.77  ? 618 HOH H O   1 
HETATM 26925 O O   . HOH P 2 .   ? -14.449 -46.298 54.883  1.00 28.72  ? 619 HOH H O   1 
HETATM 26926 O O   . HOH P 2 .   ? 14.555  -26.288 60.074  1.00 24.96  ? 620 HOH H O   1 
HETATM 26927 O O   . HOH P 2 .   ? 2.879   -21.574 80.056  1.00 42.49  ? 621 HOH H O   1 
HETATM 26928 O O   . HOH P 2 .   ? -0.156  -62.257 51.952  1.00 28.20  ? 622 HOH H O   1 
HETATM 26929 O O   . HOH P 2 .   ? -2.281  -61.984 50.464  1.00 33.89  ? 623 HOH H O   1 
HETATM 26930 O O   . HOH P 2 .   ? -25.520 -62.542 77.501  1.00 34.81  ? 624 HOH H O   1 
HETATM 26931 O O   . HOH P 2 .   ? 13.183  -48.291 69.873  1.00 23.67  ? 625 HOH H O   1 
HETATM 26932 O O   . HOH P 2 .   ? 19.938  -33.791 61.270  1.00 32.52  ? 626 HOH H O   1 
HETATM 26933 O O   . HOH P 2 .   ? 14.460  -51.470 77.239  1.00 41.32  ? 627 HOH H O   1 
HETATM 26934 O O   . HOH P 2 .   ? 0.418   -43.189 84.288  1.00 50.56  ? 628 HOH H O   1 
HETATM 26935 O O   . HOH P 2 .   ? -7.716  -49.805 73.246  1.00 45.22  ? 629 HOH H O   1 
HETATM 26936 O O   . HOH P 2 .   ? -27.212 -61.784 77.491  1.00 27.11  ? 630 HOH H O   1 
HETATM 26937 O O   . HOH P 2 .   ? 23.934  -36.583 66.018  1.00 41.94  ? 631 HOH H O   1 
HETATM 26938 O O   . HOH P 2 .   ? -6.219  -56.166 69.465  1.00 34.12  ? 632 HOH H O   1 
HETATM 26939 O O   . HOH P 2 .   ? -4.995  -72.817 74.135  1.00 31.81  ? 633 HOH H O   1 
HETATM 26940 O O   . HOH P 2 .   ? 2.152   -42.394 82.082  1.00 46.03  ? 634 HOH H O   1 
HETATM 26941 O O   . HOH P 2 .   ? 16.666  -60.427 78.741  1.00 38.24  ? 635 HOH H O   1 
HETATM 26942 O O   . HOH P 2 .   ? 13.510  -58.001 63.725  1.00 29.28  ? 636 HOH H O   1 
HETATM 26943 O O   . HOH P 2 .   ? 16.718  -22.858 69.247  1.00 27.71  ? 637 HOH H O   1 
HETATM 26944 O O   . HOH P 2 .   ? 14.203  -26.627 43.655  1.00 38.48  ? 638 HOH H O   1 
HETATM 26945 O O   . HOH P 2 .   ? 15.831  -38.448 52.454  1.00 33.78  ? 639 HOH H O   1 
HETATM 26946 O O   . HOH P 2 .   ? 20.747  -44.796 75.613  1.00 36.01  ? 640 HOH H O   1 
HETATM 26947 O O   . HOH P 2 .   ? -13.904 -41.511 85.269  1.00 38.47  ? 641 HOH H O   1 
HETATM 26948 O O   . HOH P 2 .   ? 16.098  -54.246 69.843  1.00 41.94  ? 642 HOH H O   1 
HETATM 26949 O O   . HOH P 2 .   ? 18.538  -24.947 69.853  1.00 37.87  ? 643 HOH H O   1 
HETATM 26950 O O   . HOH P 2 .   ? -25.734 -48.936 65.549  1.00 42.94  ? 644 HOH H O   1 
HETATM 26951 O O   . HOH P 2 .   ? -6.970  -53.126 68.936  1.00 41.18  ? 645 HOH H O   1 
HETATM 26952 O O   . HOH P 2 .   ? -6.872  -66.308 78.498  1.00 34.58  ? 646 HOH H O   1 
HETATM 26953 O O   . HOH P 2 .   ? 20.836  -44.163 58.547  1.00 33.95  ? 647 HOH H O   1 
HETATM 26954 O O   . HOH P 2 .   ? 0.507   -50.250 57.139  1.00 31.95  ? 648 HOH H O   1 
HETATM 26955 O O   . HOH P 2 .   ? 28.113  -31.040 63.834  1.00 43.72  ? 649 HOH H O   1 
HETATM 26956 O O   . HOH P 2 .   ? 11.158  -51.688 57.067  1.00 30.30  ? 650 HOH H O   1 
HETATM 26957 O O   . HOH P 2 .   ? 19.759  -50.048 63.283  1.00 37.51  ? 651 HOH H O   1 
HETATM 26958 O O   . HOH P 2 .   ? -12.563 -43.729 89.863  1.00 46.59  ? 652 HOH H O   1 
HETATM 26959 O O   . HOH P 2 .   ? 15.226  -60.991 60.001  1.00 31.64  ? 653 HOH H O   1 
HETATM 26960 O O   . HOH P 2 .   ? 5.618   -14.928 67.380  1.00 33.01  ? 654 HOH H O   1 
HETATM 26961 O O   . HOH P 2 .   ? -16.304 -44.786 71.163  1.00 46.16  ? 655 HOH H O   1 
HETATM 26962 O O   . HOH P 2 .   ? -10.919 -61.568 45.024  1.00 37.56  ? 656 HOH H O   1 
HETATM 26963 O O   . HOH P 2 .   ? -16.808 -45.519 68.407  1.00 47.07  ? 657 HOH H O   1 
HETATM 26964 O O   . HOH P 2 .   ? 4.699   -63.538 50.657  1.00 41.15  ? 658 HOH H O   1 
HETATM 26965 O O   . HOH P 2 .   ? -6.380  -65.678 45.230  1.00 43.86  ? 659 HOH H O   1 
HETATM 26966 O O   . HOH P 2 .   ? 8.308   -45.385 52.784  1.00 31.61  ? 660 HOH H O   1 
HETATM 26967 O O   . HOH P 2 .   ? -24.701 -63.970 76.753  1.00 33.56  ? 661 HOH H O   1 
HETATM 26968 O O   . HOH P 2 .   ? -2.015  -23.196 61.263  1.00 41.77  ? 662 HOH H O   1 
HETATM 26969 O O   . HOH P 2 .   ? 10.523  -47.748 59.733  1.00 34.41  ? 663 HOH H O   1 
HETATM 26970 O O   . HOH P 2 .   ? 9.217   -66.288 65.804  1.00 27.74  ? 664 HOH H O   1 
HETATM 26971 O O   . HOH P 2 .   ? -24.146 -65.957 75.891  1.00 38.03  ? 665 HOH H O   1 
HETATM 26972 O O   . HOH P 2 .   ? 2.626   -52.525 53.122  1.00 34.48  ? 666 HOH H O   1 
HETATM 26973 O O   . HOH P 2 .   ? 1.581   -61.685 49.806  1.00 38.63  ? 667 HOH H O   1 
HETATM 26974 O O   . HOH P 2 .   ? -12.679 -35.739 46.570  1.00 52.71  ? 668 HOH H O   1 
HETATM 26975 O O   . HOH P 2 .   ? -1.099  -73.446 74.093  1.00 56.46  ? 669 HOH H O   1 
HETATM 26976 O O   . HOH P 2 .   ? 9.095   -45.690 54.810  1.00 50.27  ? 670 HOH H O   1 
HETATM 26977 O O   . HOH P 2 .   ? 9.306   -58.031 49.433  1.00 38.54  ? 671 HOH H O   1 
HETATM 26978 O O   . HOH P 2 .   ? 7.077   -54.063 51.064  1.00 42.69  ? 672 HOH H O   1 
HETATM 26979 O O   . HOH P 2 .   ? 13.825  -43.746 56.568  1.00 37.01  ? 673 HOH H O   1 
HETATM 26980 O O   . HOH P 2 .   ? -1.520  -67.384 66.105  1.00 39.05  ? 674 HOH H O   1 
HETATM 26981 O O   . HOH P 2 .   ? 23.446  -35.946 63.799  1.00 49.88  ? 675 HOH H O   1 
HETATM 26982 O O   . HOH P 2 .   ? -7.218  -39.723 91.394  1.00 37.05  ? 676 HOH H O   1 
HETATM 26983 O O   . HOH P 2 .   ? 10.468  -45.208 58.339  1.00 37.72  ? 677 HOH H O   1 
HETATM 26984 O O   . HOH P 2 .   ? -14.716 -44.704 90.477  1.00 40.41  ? 678 HOH H O   1 
HETATM 26985 O O   . HOH P 2 .   ? 12.645  -45.945 55.922  1.00 46.52  ? 679 HOH H O   1 
HETATM 26986 O O   . HOH P 2 .   ? -24.978 -65.112 74.163  1.00 40.53  ? 680 HOH H O   1 
HETATM 26987 O O   . HOH P 2 .   ? 16.410  -41.565 54.837  1.00 43.20  ? 681 HOH H O   1 
HETATM 26988 O O   . HOH P 2 .   ? 14.312  -50.762 60.255  1.00 21.37  ? 682 HOH H O   1 
HETATM 26989 O O   . HOH P 2 .   ? 9.446   -47.793 53.094  1.00 41.36  ? 683 HOH H O   1 
HETATM 26990 O O   . HOH P 2 .   ? 3.480   -50.158 52.868  1.00 27.76  ? 684 HOH H O   1 
HETATM 26991 O O   . HOH P 2 .   ? 25.746  -23.776 68.246  1.00 36.27  ? 685 HOH H O   1 
HETATM 26992 O O   . HOH P 2 .   ? 29.780  -42.555 69.740  1.00 46.30  ? 686 HOH H O   1 
HETATM 26993 O O   . HOH P 2 .   ? 12.584  -58.767 68.604  1.00 28.99  ? 687 HOH H O   1 
HETATM 26994 O O   . HOH P 2 .   ? 5.482   -62.425 48.377  1.00 47.15  ? 688 HOH H O   1 
HETATM 26995 O O   . HOH P 2 .   ? 12.245  -47.102 52.764  1.00 49.06  ? 689 HOH H O   1 
HETATM 26996 O O   . HOH P 2 .   ? 27.043  -26.508 68.530  1.00 46.76  ? 690 HOH H O   1 
HETATM 26997 O O   . HOH P 2 .   ? 13.962  -56.277 69.365  1.00 53.98  ? 691 HOH H O   1 
HETATM 26998 O O   . HOH P 2 .   ? 29.453  -39.872 68.618  1.00 50.48  ? 692 HOH H O   1 
HETATM 26999 O O   . HOH P 2 .   ? -26.148 -64.851 91.744  1.00 44.46  ? 693 HOH H O   1 
HETATM 27000 O O   . HOH P 2 .   ? 17.334  -58.329 80.306  1.00 48.46  ? 694 HOH H O   1 
HETATM 27001 O O   . HOH P 2 .   ? -20.119 -41.638 51.350  1.00 43.92  ? 695 HOH H O   1 
HETATM 27002 O O   . HOH P 2 .   ? -7.712  -37.881 92.950  1.00 40.65  ? 696 HOH H O   1 
HETATM 27003 O O   . HOH P 2 .   ? -31.759 -66.225 76.843  1.00 58.53  ? 697 HOH H O   1 
HETATM 27004 O O   . HOH P 2 .   ? -32.748 -66.660 79.438  1.00 50.07  ? 698 HOH H O   1 
# 
