data_8YLK
# 
_entry.id   8YLK 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8YLK         pdb_00008ylk 10.2210/pdb8ylk/pdb 
WWPDB D_1300045763 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-13 
2 'Structure model' 1 1 2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.page_first'     
3 2 'Structure model' '_citation.page_last'      
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8YLK 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-06 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              sungil@kangwon.ac.kr 
_pdbx_contact_author.name_first         Sung-il 
_pdbx_contact_author.name_last          Yoon 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0777-0457 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Song, W.S.' 1 0000-0002-8104-8027 
'Yoon, S.I.' 2 0000-0003-0777-0457 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nucleic Acids Res.' 
_citation.journal_id_ASTM           NARHAD 
_citation.journal_id_CSD            0389 
_citation.journal_id_ISSN           1362-4962 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            52 
_citation.language                  ? 
_citation.page_first                13192 
_citation.page_last                 13205 
_citation.title                     'Structural basis of transcriptional regulation by UrtR in response to uric acid.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1093/nar/gkae922 
_citation.pdbx_database_id_PubMed   39484741 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Song, W.S.' 1 ?                   
primary 'Ki, D.U.'   2 ?                   
primary 'Cho, H.Y.'  3 ?                   
primary 'Kwon, O.H.' 4 ?                   
primary 'Cho, H.'    5 ?                   
primary 'Yoon, S.I.' 6 0000-0003-0777-0457 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'MarR family transcriptional regulator' 18337.809 1 ? ? ? ? 
2 non-polymer syn 'URIC ACID'                             168.110   1 ? ? ? ? 
3 water       nat water                                   18.015    6 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SAKDPMDRAAHAVEQWRSERPDLDPSSMIVLGRLQEAALVIARDRLNPLFARYGLQPGEFDVLATLRRSGAPYALTPTAL
YDAAMISSGSMTNRIDRLEKAGWVERRANPADGRGTLVALTSAGRALIDDAVVAHVDNQRRVLSALSAAEQRQLAKLLDK
LLQGQAAEG
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SAKDPMDRAAHAVEQWRSERPDLDPSSMIVLGRLQEAALVIARDRLNPLFARYGLQPGEFDVLATLRRSGAPYALTPTAL
YDAAMISSGSMTNRIDRLEKAGWVERRANPADGRGTLVALTSAGRALIDDAVVAHVDNQRRVLSALSAAEQRQLAKLLDK
LLQGQAAEG
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'URIC ACID' URC 
3 water       HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   ALA n 
1 3   LYS n 
1 4   ASP n 
1 5   PRO n 
1 6   MET n 
1 7   ASP n 
1 8   ARG n 
1 9   ALA n 
1 10  ALA n 
1 11  HIS n 
1 12  ALA n 
1 13  VAL n 
1 14  GLU n 
1 15  GLN n 
1 16  TRP n 
1 17  ARG n 
1 18  SER n 
1 19  GLU n 
1 20  ARG n 
1 21  PRO n 
1 22  ASP n 
1 23  LEU n 
1 24  ASP n 
1 25  PRO n 
1 26  SER n 
1 27  SER n 
1 28  MET n 
1 29  ILE n 
1 30  VAL n 
1 31  LEU n 
1 32  GLY n 
1 33  ARG n 
1 34  LEU n 
1 35  GLN n 
1 36  GLU n 
1 37  ALA n 
1 38  ALA n 
1 39  LEU n 
1 40  VAL n 
1 41  ILE n 
1 42  ALA n 
1 43  ARG n 
1 44  ASP n 
1 45  ARG n 
1 46  LEU n 
1 47  ASN n 
1 48  PRO n 
1 49  LEU n 
1 50  PHE n 
1 51  ALA n 
1 52  ARG n 
1 53  TYR n 
1 54  GLY n 
1 55  LEU n 
1 56  GLN n 
1 57  PRO n 
1 58  GLY n 
1 59  GLU n 
1 60  PHE n 
1 61  ASP n 
1 62  VAL n 
1 63  LEU n 
1 64  ALA n 
1 65  THR n 
1 66  LEU n 
1 67  ARG n 
1 68  ARG n 
1 69  SER n 
1 70  GLY n 
1 71  ALA n 
1 72  PRO n 
1 73  TYR n 
1 74  ALA n 
1 75  LEU n 
1 76  THR n 
1 77  PRO n 
1 78  THR n 
1 79  ALA n 
1 80  LEU n 
1 81  TYR n 
1 82  ASP n 
1 83  ALA n 
1 84  ALA n 
1 85  MET n 
1 86  ILE n 
1 87  SER n 
1 88  SER n 
1 89  GLY n 
1 90  SER n 
1 91  MET n 
1 92  THR n 
1 93  ASN n 
1 94  ARG n 
1 95  ILE n 
1 96  ASP n 
1 97  ARG n 
1 98  LEU n 
1 99  GLU n 
1 100 LYS n 
1 101 ALA n 
1 102 GLY n 
1 103 TRP n 
1 104 VAL n 
1 105 GLU n 
1 106 ARG n 
1 107 ARG n 
1 108 ALA n 
1 109 ASN n 
1 110 PRO n 
1 111 ALA n 
1 112 ASP n 
1 113 GLY n 
1 114 ARG n 
1 115 GLY n 
1 116 THR n 
1 117 LEU n 
1 118 VAL n 
1 119 ALA n 
1 120 LEU n 
1 121 THR n 
1 122 SER n 
1 123 ALA n 
1 124 GLY n 
1 125 ARG n 
1 126 ALA n 
1 127 LEU n 
1 128 ILE n 
1 129 ASP n 
1 130 ASP n 
1 131 ALA n 
1 132 VAL n 
1 133 VAL n 
1 134 ALA n 
1 135 HIS n 
1 136 VAL n 
1 137 ASP n 
1 138 ASN n 
1 139 GLN n 
1 140 ARG n 
1 141 ARG n 
1 142 VAL n 
1 143 LEU n 
1 144 SER n 
1 145 ALA n 
1 146 LEU n 
1 147 SER n 
1 148 ALA n 
1 149 ALA n 
1 150 GLU n 
1 151 GLN n 
1 152 ARG n 
1 153 GLN n 
1 154 LEU n 
1 155 ALA n 
1 156 LYS n 
1 157 LEU n 
1 158 LEU n 
1 159 ASP n 
1 160 LYS n 
1 161 LEU n 
1 162 LEU n 
1 163 GLN n 
1 164 GLY n 
1 165 GLN n 
1 166 ALA n 
1 167 ALA n 
1 168 GLU n 
1 169 GLY n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   169 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 A8H32_16025 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Burkholderia thailandensis' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     57975 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                                        'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?                                        'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                                        'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                                        'C4 H7 N O4'     133.103 
GLN 'L-peptide linking' y GLUTAMINE       ?                                        'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                                        'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?                                        'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ?                                        'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ?                                        'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ?                                        'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?                                        'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?                                        'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?                                        'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?                                        'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?                                        'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ?                                        'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ?                                        'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                                        'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?                                        'C9 H11 N O3'    181.189 
URC non-polymer         . 'URIC ACID'     '7,9-DIHYDRO-1H-PURINE-2,6,8(3H)-TRIONE' 'C5 H4 N4 O3'    168.110 
VAL 'L-peptide linking' y VALINE          ?                                        'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   -4  ?   ?   ?   A . n 
A 1 2   ALA 2   -3  ?   ?   ?   A . n 
A 1 3   LYS 3   -2  ?   ?   ?   A . n 
A 1 4   ASP 4   -1  ?   ?   ?   A . n 
A 1 5   PRO 5   0   ?   ?   ?   A . n 
A 1 6   MET 6   1   1   MET MET A . n 
A 1 7   ASP 7   2   2   ASP ASP A . n 
A 1 8   ARG 8   3   3   ARG ARG A . n 
A 1 9   ALA 9   4   4   ALA ALA A . n 
A 1 10  ALA 10  5   5   ALA ALA A . n 
A 1 11  HIS 11  6   6   HIS HIS A . n 
A 1 12  ALA 12  7   7   ALA ALA A . n 
A 1 13  VAL 13  8   8   VAL VAL A . n 
A 1 14  GLU 14  9   9   GLU GLU A . n 
A 1 15  GLN 15  10  10  GLN GLN A . n 
A 1 16  TRP 16  11  11  TRP TRP A . n 
A 1 17  ARG 17  12  12  ARG ARG A . n 
A 1 18  SER 18  13  13  SER SER A . n 
A 1 19  GLU 19  14  14  GLU GLU A . n 
A 1 20  ARG 20  15  15  ARG ARG A . n 
A 1 21  PRO 21  16  16  PRO PRO A . n 
A 1 22  ASP 22  17  17  ASP ASP A . n 
A 1 23  LEU 23  18  18  LEU LEU A . n 
A 1 24  ASP 24  19  19  ASP ASP A . n 
A 1 25  PRO 25  20  20  PRO PRO A . n 
A 1 26  SER 26  21  21  SER SER A . n 
A 1 27  SER 27  22  22  SER SER A . n 
A 1 28  MET 28  23  23  MET MET A . n 
A 1 29  ILE 29  24  24  ILE ILE A . n 
A 1 30  VAL 30  25  25  VAL VAL A . n 
A 1 31  LEU 31  26  26  LEU LEU A . n 
A 1 32  GLY 32  27  27  GLY GLY A . n 
A 1 33  ARG 33  28  28  ARG ARG A . n 
A 1 34  LEU 34  29  29  LEU LEU A . n 
A 1 35  GLN 35  30  30  GLN GLN A . n 
A 1 36  GLU 36  31  31  GLU GLU A . n 
A 1 37  ALA 37  32  32  ALA ALA A . n 
A 1 38  ALA 38  33  33  ALA ALA A . n 
A 1 39  LEU 39  34  34  LEU LEU A . n 
A 1 40  VAL 40  35  35  VAL VAL A . n 
A 1 41  ILE 41  36  36  ILE ILE A . n 
A 1 42  ALA 42  37  37  ALA ALA A . n 
A 1 43  ARG 43  38  38  ARG ARG A . n 
A 1 44  ASP 44  39  39  ASP ASP A . n 
A 1 45  ARG 45  40  40  ARG ARG A . n 
A 1 46  LEU 46  41  41  LEU LEU A . n 
A 1 47  ASN 47  42  42  ASN ASN A . n 
A 1 48  PRO 48  43  43  PRO PRO A . n 
A 1 49  LEU 49  44  44  LEU LEU A . n 
A 1 50  PHE 50  45  45  PHE PHE A . n 
A 1 51  ALA 51  46  46  ALA ALA A . n 
A 1 52  ARG 52  47  47  ARG ARG A . n 
A 1 53  TYR 53  48  48  TYR TYR A . n 
A 1 54  GLY 54  49  49  GLY GLY A . n 
A 1 55  LEU 55  50  50  LEU LEU A . n 
A 1 56  GLN 56  51  51  GLN GLN A . n 
A 1 57  PRO 57  52  52  PRO PRO A . n 
A 1 58  GLY 58  53  53  GLY GLY A . n 
A 1 59  GLU 59  54  54  GLU GLU A . n 
A 1 60  PHE 60  55  55  PHE PHE A . n 
A 1 61  ASP 61  56  56  ASP ASP A . n 
A 1 62  VAL 62  57  57  VAL VAL A . n 
A 1 63  LEU 63  58  58  LEU LEU A . n 
A 1 64  ALA 64  59  59  ALA ALA A . n 
A 1 65  THR 65  60  60  THR THR A . n 
A 1 66  LEU 66  61  61  LEU LEU A . n 
A 1 67  ARG 67  62  62  ARG ARG A . n 
A 1 68  ARG 68  63  63  ARG ARG A . n 
A 1 69  SER 69  64  64  SER SER A . n 
A 1 70  GLY 70  65  65  GLY GLY A . n 
A 1 71  ALA 71  66  66  ALA ALA A . n 
A 1 72  PRO 72  67  67  PRO PRO A . n 
A 1 73  TYR 73  68  68  TYR TYR A . n 
A 1 74  ALA 74  69  69  ALA ALA A . n 
A 1 75  LEU 75  70  70  LEU LEU A . n 
A 1 76  THR 76  71  71  THR THR A . n 
A 1 77  PRO 77  72  72  PRO PRO A . n 
A 1 78  THR 78  73  73  THR THR A . n 
A 1 79  ALA 79  74  74  ALA ALA A . n 
A 1 80  LEU 80  75  75  LEU LEU A . n 
A 1 81  TYR 81  76  76  TYR TYR A . n 
A 1 82  ASP 82  77  77  ASP ASP A . n 
A 1 83  ALA 83  78  78  ALA ALA A . n 
A 1 84  ALA 84  79  79  ALA ALA A . n 
A 1 85  MET 85  80  80  MET MET A . n 
A 1 86  ILE 86  81  81  ILE ILE A . n 
A 1 87  SER 87  82  82  SER SER A . n 
A 1 88  SER 88  83  83  SER SER A . n 
A 1 89  GLY 89  84  84  GLY GLY A . n 
A 1 90  SER 90  85  85  SER SER A . n 
A 1 91  MET 91  86  86  MET MET A . n 
A 1 92  THR 92  87  87  THR THR A . n 
A 1 93  ASN 93  88  88  ASN ASN A . n 
A 1 94  ARG 94  89  89  ARG ARG A . n 
A 1 95  ILE 95  90  90  ILE ILE A . n 
A 1 96  ASP 96  91  91  ASP ASP A . n 
A 1 97  ARG 97  92  92  ARG ARG A . n 
A 1 98  LEU 98  93  93  LEU LEU A . n 
A 1 99  GLU 99  94  94  GLU GLU A . n 
A 1 100 LYS 100 95  95  LYS LYS A . n 
A 1 101 ALA 101 96  96  ALA ALA A . n 
A 1 102 GLY 102 97  97  GLY GLY A . n 
A 1 103 TRP 103 98  98  TRP TRP A . n 
A 1 104 VAL 104 99  99  VAL VAL A . n 
A 1 105 GLU 105 100 100 GLU GLU A . n 
A 1 106 ARG 106 101 101 ARG ARG A . n 
A 1 107 ARG 107 102 102 ARG ARG A . n 
A 1 108 ALA 108 103 103 ALA ALA A . n 
A 1 109 ASN 109 104 ?   ?   ?   A . n 
A 1 110 PRO 110 105 ?   ?   ?   A . n 
A 1 111 ALA 111 106 ?   ?   ?   A . n 
A 1 112 ASP 112 107 ?   ?   ?   A . n 
A 1 113 GLY 113 108 ?   ?   ?   A . n 
A 1 114 ARG 114 109 ?   ?   ?   A . n 
A 1 115 GLY 115 110 ?   ?   ?   A . n 
A 1 116 THR 116 111 111 THR THR A . n 
A 1 117 LEU 117 112 112 LEU LEU A . n 
A 1 118 VAL 118 113 113 VAL VAL A . n 
A 1 119 ALA 119 114 114 ALA ALA A . n 
A 1 120 LEU 120 115 115 LEU LEU A . n 
A 1 121 THR 121 116 116 THR THR A . n 
A 1 122 SER 122 117 117 SER SER A . n 
A 1 123 ALA 123 118 118 ALA ALA A . n 
A 1 124 GLY 124 119 119 GLY GLY A . n 
A 1 125 ARG 125 120 120 ARG ARG A . n 
A 1 126 ALA 126 121 121 ALA ALA A . n 
A 1 127 LEU 127 122 122 LEU LEU A . n 
A 1 128 ILE 128 123 123 ILE ILE A . n 
A 1 129 ASP 129 124 124 ASP ASP A . n 
A 1 130 ASP 130 125 125 ASP ASP A . n 
A 1 131 ALA 131 126 126 ALA ALA A . n 
A 1 132 VAL 132 127 127 VAL VAL A . n 
A 1 133 VAL 133 128 128 VAL VAL A . n 
A 1 134 ALA 134 129 129 ALA ALA A . n 
A 1 135 HIS 135 130 130 HIS HIS A . n 
A 1 136 VAL 136 131 131 VAL VAL A . n 
A 1 137 ASP 137 132 132 ASP ASP A . n 
A 1 138 ASN 138 133 133 ASN ASN A . n 
A 1 139 GLN 139 134 134 GLN GLN A . n 
A 1 140 ARG 140 135 135 ARG ARG A . n 
A 1 141 ARG 141 136 136 ARG ARG A . n 
A 1 142 VAL 142 137 137 VAL VAL A . n 
A 1 143 LEU 143 138 138 LEU LEU A . n 
A 1 144 SER 144 139 139 SER SER A . n 
A 1 145 ALA 145 140 140 ALA ALA A . n 
A 1 146 LEU 146 141 141 LEU LEU A . n 
A 1 147 SER 147 142 142 SER SER A . n 
A 1 148 ALA 148 143 143 ALA ALA A . n 
A 1 149 ALA 149 144 144 ALA ALA A . n 
A 1 150 GLU 150 145 145 GLU GLU A . n 
A 1 151 GLN 151 146 146 GLN GLN A . n 
A 1 152 ARG 152 147 147 ARG ARG A . n 
A 1 153 GLN 153 148 148 GLN GLN A . n 
A 1 154 LEU 154 149 149 LEU LEU A . n 
A 1 155 ALA 155 150 150 ALA ALA A . n 
A 1 156 LYS 156 151 151 LYS LYS A . n 
A 1 157 LEU 157 152 152 LEU LEU A . n 
A 1 158 LEU 158 153 153 LEU LEU A . n 
A 1 159 ASP 159 154 154 ASP ASP A . n 
A 1 160 LYS 160 155 155 LYS LYS A . n 
A 1 161 LEU 161 156 156 LEU LEU A . n 
A 1 162 LEU 162 157 157 LEU LEU A . n 
A 1 163 GLN 163 158 158 GLN GLN A . n 
A 1 164 GLY 164 159 159 GLY GLY A . n 
A 1 165 GLN 165 160 160 GLN GLN A . n 
A 1 166 ALA 166 161 ?   ?   ?   A . n 
A 1 167 ALA 167 162 ?   ?   ?   A . n 
A 1 168 GLU 168 163 ?   ?   ?   A . n 
A 1 169 GLY 169 164 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        URC 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   URC 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 URC 1 201 1  URC URC A . 
C 3 HOH 1 301 11 HOH HOH A . 
C 3 HOH 2 302 2  HOH HOH A . 
C 3 HOH 3 303 21 HOH HOH A . 
C 3 HOH 4 304 6  HOH HOH A . 
C 3 HOH 5 305 10 HOH HOH A . 
C 3 HOH 6 306 1  HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 95  ? CE  ? A LYS 100 CE  
2  1 Y 1 A LYS 95  ? NZ  ? A LYS 100 NZ  
3  1 Y 1 A ARG 102 ? CG  ? A ARG 107 CG  
4  1 Y 1 A ARG 102 ? CD  ? A ARG 107 CD  
5  1 Y 1 A ARG 102 ? NE  ? A ARG 107 NE  
6  1 Y 1 A ARG 102 ? CZ  ? A ARG 107 CZ  
7  1 Y 1 A ARG 102 ? NH1 ? A ARG 107 NH1 
8  1 Y 1 A ARG 102 ? NH2 ? A ARG 107 NH2 
9  1 Y 1 A ASP 132 ? CG  ? A ASP 137 CG  
10 1 Y 1 A ASP 132 ? OD1 ? A ASP 137 OD1 
11 1 Y 1 A ASP 132 ? OD2 ? A ASP 137 OD2 
12 1 Y 1 A ARG 147 ? CG  ? A ARG 152 CG  
13 1 Y 1 A ARG 147 ? CD  ? A ARG 152 CD  
14 1 Y 1 A ARG 147 ? NE  ? A ARG 152 NE  
15 1 Y 1 A ARG 147 ? CZ  ? A ARG 152 CZ  
16 1 Y 1 A ARG 147 ? NH1 ? A ARG 152 NH1 
17 1 Y 1 A ARG 147 ? NH2 ? A ARG 152 NH2 
18 1 Y 1 A GLN 148 ? CD  ? A GLN 153 CD  
19 1 Y 1 A GLN 148 ? OE1 ? A GLN 153 OE1 
20 1 Y 1 A GLN 148 ? NE2 ? A GLN 153 NE2 
21 1 Y 1 A LYS 151 ? CD  ? A LYS 156 CD  
22 1 Y 1 A LYS 151 ? CE  ? A LYS 156 CE  
23 1 Y 1 A LYS 151 ? NZ  ? A LYS 156 NZ  
24 1 Y 1 A GLN 158 ? CD  ? A GLN 163 CD  
25 1 Y 1 A GLN 158 ? OE1 ? A GLN 163 OE1 
26 1 Y 1 A GLN 158 ? NE2 ? A GLN 163 NE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.15.2_3472 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8YLK 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     62.942 
_cell.length_a_esd                 ? 
_cell.length_b                     62.942 
_cell.length_b_esd                 ? 
_cell.length_c                     77.568 
_cell.length_c_esd                 ? 
_cell.volume                       266130.287 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8YLK 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                152 
_symmetry.space_group_name_Hall            
;P 31 2"
;
_symmetry.space_group_name_H-M             'P 31 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8YLK 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.42 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          49.15 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'ADSC QUANTUM 270' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-07-01 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9793 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PAL/PLS BEAMLINE 7A (6B, 6C1)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9793 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   '7A (6B, 6C1)' 
_diffrn_source.pdbx_synchrotron_site       PAL/PLS 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8YLK 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.10 
_reflns.d_resolution_low                               30.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     10766 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.7 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          31.2 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.057 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.10 
_reflns_shell.d_res_low                                     2.14 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.4 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             507 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               4.8 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.6 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.489 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               55.83 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8YLK 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.10 
_refine.ls_d_res_low                             27.25 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     10696 
_refine.ls_number_reflns_R_free                  575 
_refine.ls_number_reflns_R_work                  10121 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.33 
_refine.ls_percent_reflns_R_free                 5.38 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2286 
_refine.ls_R_factor_R_free                       0.2606 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2269 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      8YLF 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 32.1039 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2804 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.10 
_refine_hist.d_res_low                        27.25 
_refine_hist.number_atoms_solvent             6 
_refine_hist.number_atoms_total               1173 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1155 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         12 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0029  ? 1183 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.5709  ? 1606 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0341  ? 188  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0041  ? 209  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 11.9624 ? 731  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.10 2.31  . . 118 2477 98.41 . . . . 0.2950 . . . . . . . . . . . 0.3400 
'X-RAY DIFFRACTION' 2.31 2.65  . . 149 2485 99.47 . . . . 0.2522 . . . . . . . . . . . 0.3224 
'X-RAY DIFFRACTION' 2.65 3.33  . . 143 2543 99.89 . . . . 0.2658 . . . . . . . . . . . 0.2727 
'X-RAY DIFFRACTION' 3.33 27.25 . . 165 2616 99.53 . . . . 0.1979 . . . . . . . . . . . 0.2348 
# 
_struct.entry_id                     8YLK 
_struct.title                        'Crystal structure of Burkholderia thailandensis MftR in complex with uric acid' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8YLK 
_struct_keywords.text            'Transcription factor, TRANSCRIPTION' 
_struct_keywords.pdbx_keywords   TRANSCRIPTION 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A2N8QSC4_BURTH 
_struct_ref.pdbx_db_accession          A0A2N8QSC4 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MDRAAHAVEQWRSERPDLDPSSMIVLGRLQEAALVIARDRLNPLFARYGLQPGEFDVLATLRRSGAPYALTPTALYDAAM
ISSGSMTNRIDRLEKAGWVERRANPADGRGTLVALTSAGRALIDDAVVAHVDNQRRVLSALSAAEQRQLAKLLDKLLQGQ
AAEG
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8YLK 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 6 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 169 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A2N8QSC4 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  164 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       164 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8YLK SER A 1 ? UNP A0A2N8QSC4 ? ? 'expression tag' -4 1 
1 8YLK ALA A 2 ? UNP A0A2N8QSC4 ? ? 'expression tag' -3 2 
1 8YLK LYS A 3 ? UNP A0A2N8QSC4 ? ? 'expression tag' -2 3 
1 8YLK ASP A 4 ? UNP A0A2N8QSC4 ? ? 'expression tag' -1 4 
1 8YLK PRO A 5 ? UNP A0A2N8QSC4 ? ? 'expression tag' 0  5 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 7760  ? 
1 MORE         -50   ? 
1 'SSA (A^2)'  12800 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z          1.0000000000  0.0000000000  0.0000000000 0.0000000000 0.0000000000  
1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000  
2 'crystal symmetry operation' 6_555 -x,-x+y,-z+1/3 -0.5000000000 -0.8660254038 0.0000000000 0.0000000000 -0.8660254038 
0.5000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 25.8560000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ASP A 7   ? ARG A 20  ? ASP A 2   ARG A 15  1 ? 14 
HELX_P HELX_P2 AA2 ASP A 24  ? SER A 26  ? ASP A 19  SER A 21  5 ? 3  
HELX_P HELX_P3 AA3 SER A 27  ? ARG A 45  ? SER A 22  ARG A 40  1 ? 19 
HELX_P HELX_P4 AA4 ARG A 45  ? TYR A 53  ? ARG A 40  TYR A 48  1 ? 9  
HELX_P HELX_P5 AA5 GLY A 58  ? SER A 69  ? GLY A 53  SER A 64  1 ? 12 
HELX_P HELX_P6 AA6 THR A 76  ? ALA A 84  ? THR A 71  ALA A 79  1 ? 9  
HELX_P HELX_P7 AA7 SER A 90  ? ALA A 101 ? SER A 85  ALA A 96  1 ? 12 
HELX_P HELX_P8 AA8 THR A 121 ? LEU A 143 ? THR A 116 LEU A 138 1 ? 23 
HELX_P HELX_P9 AA9 SER A 147 ? GLY A 164 ? SER A 142 GLY A 159 1 ? 18 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          ALA 
_struct_mon_prot_cis.label_seq_id           71 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           ALA 
_struct_mon_prot_cis.auth_seq_id            66 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    72 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     67 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       3.02 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   3 
_struct_sheet.details          ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 74  ? LEU A 75  ? ALA A 69  LEU A 70  
AA1 2 LEU A 117 ? LEU A 120 ? LEU A 112 LEU A 115 
AA1 3 VAL A 104 ? ARG A 107 ? VAL A 99  ARG A 102 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 75  ? N LEU A 70  O VAL A 118 ? O VAL A 113 
AA1 2 3 O ALA A 119 ? O ALA A 114 N GLU A 105 ? N GLU A 100 
# 
_pdbx_entry_details.entry_id                   8YLK 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    ARG 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     40 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             -123.04 
_pdbx_validate_torsion.psi             -59.81 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+1/3   
3 -x+y,-x,z+2/3  
4 x-y,-y,-z+2/3  
5 -x,-x+y,-z+1/3 
6 y,x,-z         
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined -10.6241195634 -21.4956410094 17.6098825813 0.416400578268 ? 0.129566672798   ? -0.00338989113767 
? 0.899040437863 ? -0.0552689342933 ? 0.502236737966 ? 3.58174124897 ? 1.49486978112  ? -3.50518921517  ? 5.89019125685 ? 
-2.21678332017  ? 3.51005029303  ? -0.249573095535 ? -0.117538805311 ? 0.444138865337  ? -0.0587397781711 ? 0.289962657259  ? 
1.00246480242   ? -0.0748898537034  ? -1.75164178063   ? 0.066105252051   ? 
2 'X-RAY DIFFRACTION' ? refined 7.47925175239  -17.5347113802 7.94149592007 0.477294801968 ? 0.081450092345   ? -0.0621792440557  
? 0.347338600583 ? -0.0199704145129 ? 0.303327163332 ? 7.79926857239 ? 0.832216511829 ? -2.64815341903  ? 2.05852573493 ? 
0.342421356157  ? 5.18096252767  ? -0.561066098158 ? 0.485821205095  ? -0.259711441976 ? -0.0151250452319 ? 0.216182289463  ? 
0.224616027095  ? -0.00362649275307 ? -0.528859955961  ? 0.146567731233   ? 
3 'X-RAY DIFFRACTION' ? refined 26.9231854624  -14.570507935  6.02261507879 0.546801974917 ? -0.0443813891621 ? 0.0015006470041   
? 0.540657339674 ? 0.0208483868552  ? 0.329273984179 ? 6.94430699487 ? 3.71245519183  ? 0.140191422772  ? 6.56777639499 ? 
1.51390223472   ? 4.62240423187  ? -0.089614288066 ? 0.380591391351  ? -0.129887171956 ? 0.111876921475   ? -0.197089852054 ? 
0.0866852979444 ? -0.182655499208   ? -0.0636642998382 ? 0.189680352741   ? 
4 'X-RAY DIFFRACTION' ? refined 30.1425359585  -16.7262705028 13.0825084766 0.579237340907 ? 0.0346583067786  ? -0.00514014292487 
? 0.669096887035 ? 0.132800211769   ? 0.316558899485 ? 3.69072023478 ? 1.57519764415  ? -0.690598185634 ? 2.59418453288 ? 
-0.361863006838 ? 5.52237028713  ? 0.0310017181022 ? -0.645935401174 ? -0.279482091941 ? 0.300085585883   ? -0.336622723385 ? 
-0.226450320343 ? 0.288058488738    ? 0.834507266891   ? 0.3679658617     ? 
5 'X-RAY DIFFRACTION' ? refined 37.5501156333  -19.115344119  7.30035767406 0.619132846828 ? 0.0808419835257  ? 0.0131652351831   
? 0.778877882085 ? 0.196429978717   ? 0.549826784338 ? 2.22718982509 ? 1.33873316491  ? -2.04119345314  ? 2.75805153596 ? 
-2.7068572998   ? 3.02213804323  ? -0.30982657074  ? -0.520447286924 ? -1.13717457691  ? -0.230263856858  ? -0.200793944332 ? 
-1.34291663245  ? 0.558844223991    ? 1.53864912004    ? 0.834181718552   ? 
6 'X-RAY DIFFRACTION' ? refined 26.8064365057  -11.0494445584 1.68235972837 0.712412658377 ? -0.0386873807988 ? 0.0155447561222   
? 0.513381499069 ? 0.0359703636762  ? 0.268498276708 ? 7.26746030705 ? 1.07200640686  ? -3.83676854814  ? 2.56211755839 ? 
0.782038998106  ? 2.77037015924  ? -0.409104903148 ? 0.546225812084  ? 0.633048298612  ? -0.199873765597  ? 0.19983269815   ? 
-0.193740054425 ? -0.645146057526   ? 0.467654062872   ? -0.0707077114272 ? 
7 'X-RAY DIFFRACTION' ? refined 7.02148300161  -3.98851362042 12.4917611624 0.727502580162 ? 0.161601315432   ? 0.0222110878701   
? 0.265529927066 ? 0.0177455728531  ? 0.574453441452 ? 4.85743727589 ? 0.621789462532 ? -1.78371977212  ? 1.68700230766 ? 
0.509400475628  ? 0.995674841681 ? 0.498195329169  ? 0.213629910525  ? 1.10487981964   ? -0.0284076624348 ? -0.257651334978 ? 
0.252902134521  ? -0.731694877157   ? -0.201819006462  ? -0.197249014851  ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 1 through 19 )
;
2 'X-RAY DIFFRACTION' 2 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 20 through 47 )
;
3 'X-RAY DIFFRACTION' 3 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 48 through 64 )
;
4 'X-RAY DIFFRACTION' 4 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 65 through 96 )
;
5 'X-RAY DIFFRACTION' 5 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 97 through 102 )
;
6 'X-RAY DIFFRACTION' 6 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 103 through 137 )
;
7 'X-RAY DIFFRACTION' 7 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 138 through 160 )
;
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A SER -4  ? A SER 1   
2  1 Y 1 A ALA -3  ? A ALA 2   
3  1 Y 1 A LYS -2  ? A LYS 3   
4  1 Y 1 A ASP -1  ? A ASP 4   
5  1 Y 1 A PRO 0   ? A PRO 5   
6  1 Y 1 A ASN 104 ? A ASN 109 
7  1 Y 1 A PRO 105 ? A PRO 110 
8  1 Y 1 A ALA 106 ? A ALA 111 
9  1 Y 1 A ASP 107 ? A ASP 112 
10 1 Y 1 A GLY 108 ? A GLY 113 
11 1 Y 1 A ARG 109 ? A ARG 114 
12 1 Y 1 A GLY 110 ? A GLY 115 
13 1 Y 1 A ALA 161 ? A ALA 166 
14 1 Y 1 A ALA 162 ? A ALA 167 
15 1 Y 1 A GLU 163 ? A GLU 168 
16 1 Y 1 A GLY 164 ? A GLY 169 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
GLN N    N N N 74  
GLN CA   C N S 75  
GLN C    C N N 76  
GLN O    O N N 77  
GLN CB   C N N 78  
GLN CG   C N N 79  
GLN CD   C N N 80  
GLN OE1  O N N 81  
GLN NE2  N N N 82  
GLN OXT  O N N 83  
GLN H    H N N 84  
GLN H2   H N N 85  
GLN HA   H N N 86  
GLN HB2  H N N 87  
GLN HB3  H N N 88  
GLN HG2  H N N 89  
GLN HG3  H N N 90  
GLN HE21 H N N 91  
GLN HE22 H N N 92  
GLN HXT  H N N 93  
GLU N    N N N 94  
GLU CA   C N S 95  
GLU C    C N N 96  
GLU O    O N N 97  
GLU CB   C N N 98  
GLU CG   C N N 99  
GLU CD   C N N 100 
GLU OE1  O N N 101 
GLU OE2  O N N 102 
GLU OXT  O N N 103 
GLU H    H N N 104 
GLU H2   H N N 105 
GLU HA   H N N 106 
GLU HB2  H N N 107 
GLU HB3  H N N 108 
GLU HG2  H N N 109 
GLU HG3  H N N 110 
GLU HE2  H N N 111 
GLU HXT  H N N 112 
GLY N    N N N 113 
GLY CA   C N N 114 
GLY C    C N N 115 
GLY O    O N N 116 
GLY OXT  O N N 117 
GLY H    H N N 118 
GLY H2   H N N 119 
GLY HA2  H N N 120 
GLY HA3  H N N 121 
GLY HXT  H N N 122 
HIS N    N N N 123 
HIS CA   C N S 124 
HIS C    C N N 125 
HIS O    O N N 126 
HIS CB   C N N 127 
HIS CG   C Y N 128 
HIS ND1  N Y N 129 
HIS CD2  C Y N 130 
HIS CE1  C Y N 131 
HIS NE2  N Y N 132 
HIS OXT  O N N 133 
HIS H    H N N 134 
HIS H2   H N N 135 
HIS HA   H N N 136 
HIS HB2  H N N 137 
HIS HB3  H N N 138 
HIS HD1  H N N 139 
HIS HD2  H N N 140 
HIS HE1  H N N 141 
HIS HE2  H N N 142 
HIS HXT  H N N 143 
HOH O    O N N 144 
HOH H1   H N N 145 
HOH H2   H N N 146 
ILE N    N N N 147 
ILE CA   C N S 148 
ILE C    C N N 149 
ILE O    O N N 150 
ILE CB   C N S 151 
ILE CG1  C N N 152 
ILE CG2  C N N 153 
ILE CD1  C N N 154 
ILE OXT  O N N 155 
ILE H    H N N 156 
ILE H2   H N N 157 
ILE HA   H N N 158 
ILE HB   H N N 159 
ILE HG12 H N N 160 
ILE HG13 H N N 161 
ILE HG21 H N N 162 
ILE HG22 H N N 163 
ILE HG23 H N N 164 
ILE HD11 H N N 165 
ILE HD12 H N N 166 
ILE HD13 H N N 167 
ILE HXT  H N N 168 
LEU N    N N N 169 
LEU CA   C N S 170 
LEU C    C N N 171 
LEU O    O N N 172 
LEU CB   C N N 173 
LEU CG   C N N 174 
LEU CD1  C N N 175 
LEU CD2  C N N 176 
LEU OXT  O N N 177 
LEU H    H N N 178 
LEU H2   H N N 179 
LEU HA   H N N 180 
LEU HB2  H N N 181 
LEU HB3  H N N 182 
LEU HG   H N N 183 
LEU HD11 H N N 184 
LEU HD12 H N N 185 
LEU HD13 H N N 186 
LEU HD21 H N N 187 
LEU HD22 H N N 188 
LEU HD23 H N N 189 
LEU HXT  H N N 190 
LYS N    N N N 191 
LYS CA   C N S 192 
LYS C    C N N 193 
LYS O    O N N 194 
LYS CB   C N N 195 
LYS CG   C N N 196 
LYS CD   C N N 197 
LYS CE   C N N 198 
LYS NZ   N N N 199 
LYS OXT  O N N 200 
LYS H    H N N 201 
LYS H2   H N N 202 
LYS HA   H N N 203 
LYS HB2  H N N 204 
LYS HB3  H N N 205 
LYS HG2  H N N 206 
LYS HG3  H N N 207 
LYS HD2  H N N 208 
LYS HD3  H N N 209 
LYS HE2  H N N 210 
LYS HE3  H N N 211 
LYS HZ1  H N N 212 
LYS HZ2  H N N 213 
LYS HZ3  H N N 214 
LYS HXT  H N N 215 
MET N    N N N 216 
MET CA   C N S 217 
MET C    C N N 218 
MET O    O N N 219 
MET CB   C N N 220 
MET CG   C N N 221 
MET SD   S N N 222 
MET CE   C N N 223 
MET OXT  O N N 224 
MET H    H N N 225 
MET H2   H N N 226 
MET HA   H N N 227 
MET HB2  H N N 228 
MET HB3  H N N 229 
MET HG2  H N N 230 
MET HG3  H N N 231 
MET HE1  H N N 232 
MET HE2  H N N 233 
MET HE3  H N N 234 
MET HXT  H N N 235 
PHE N    N N N 236 
PHE CA   C N S 237 
PHE C    C N N 238 
PHE O    O N N 239 
PHE CB   C N N 240 
PHE CG   C Y N 241 
PHE CD1  C Y N 242 
PHE CD2  C Y N 243 
PHE CE1  C Y N 244 
PHE CE2  C Y N 245 
PHE CZ   C Y N 246 
PHE OXT  O N N 247 
PHE H    H N N 248 
PHE H2   H N N 249 
PHE HA   H N N 250 
PHE HB2  H N N 251 
PHE HB3  H N N 252 
PHE HD1  H N N 253 
PHE HD2  H N N 254 
PHE HE1  H N N 255 
PHE HE2  H N N 256 
PHE HZ   H N N 257 
PHE HXT  H N N 258 
PRO N    N N N 259 
PRO CA   C N S 260 
PRO C    C N N 261 
PRO O    O N N 262 
PRO CB   C N N 263 
PRO CG   C N N 264 
PRO CD   C N N 265 
PRO OXT  O N N 266 
PRO H    H N N 267 
PRO HA   H N N 268 
PRO HB2  H N N 269 
PRO HB3  H N N 270 
PRO HG2  H N N 271 
PRO HG3  H N N 272 
PRO HD2  H N N 273 
PRO HD3  H N N 274 
PRO HXT  H N N 275 
SER N    N N N 276 
SER CA   C N S 277 
SER C    C N N 278 
SER O    O N N 279 
SER CB   C N N 280 
SER OG   O N N 281 
SER OXT  O N N 282 
SER H    H N N 283 
SER H2   H N N 284 
SER HA   H N N 285 
SER HB2  H N N 286 
SER HB3  H N N 287 
SER HG   H N N 288 
SER HXT  H N N 289 
THR N    N N N 290 
THR CA   C N S 291 
THR C    C N N 292 
THR O    O N N 293 
THR CB   C N R 294 
THR OG1  O N N 295 
THR CG2  C N N 296 
THR OXT  O N N 297 
THR H    H N N 298 
THR H2   H N N 299 
THR HA   H N N 300 
THR HB   H N N 301 
THR HG1  H N N 302 
THR HG21 H N N 303 
THR HG22 H N N 304 
THR HG23 H N N 305 
THR HXT  H N N 306 
TRP N    N N N 307 
TRP CA   C N S 308 
TRP C    C N N 309 
TRP O    O N N 310 
TRP CB   C N N 311 
TRP CG   C Y N 312 
TRP CD1  C Y N 313 
TRP CD2  C Y N 314 
TRP NE1  N Y N 315 
TRP CE2  C Y N 316 
TRP CE3  C Y N 317 
TRP CZ2  C Y N 318 
TRP CZ3  C Y N 319 
TRP CH2  C Y N 320 
TRP OXT  O N N 321 
TRP H    H N N 322 
TRP H2   H N N 323 
TRP HA   H N N 324 
TRP HB2  H N N 325 
TRP HB3  H N N 326 
TRP HD1  H N N 327 
TRP HE1  H N N 328 
TRP HE3  H N N 329 
TRP HZ2  H N N 330 
TRP HZ3  H N N 331 
TRP HH2  H N N 332 
TRP HXT  H N N 333 
TYR N    N N N 334 
TYR CA   C N S 335 
TYR C    C N N 336 
TYR O    O N N 337 
TYR CB   C N N 338 
TYR CG   C Y N 339 
TYR CD1  C Y N 340 
TYR CD2  C Y N 341 
TYR CE1  C Y N 342 
TYR CE2  C Y N 343 
TYR CZ   C Y N 344 
TYR OH   O N N 345 
TYR OXT  O N N 346 
TYR H    H N N 347 
TYR H2   H N N 348 
TYR HA   H N N 349 
TYR HB2  H N N 350 
TYR HB3  H N N 351 
TYR HD1  H N N 352 
TYR HD2  H N N 353 
TYR HE1  H N N 354 
TYR HE2  H N N 355 
TYR HH   H N N 356 
TYR HXT  H N N 357 
URC N1   N Y N 358 
URC C2   C Y N 359 
URC C6   C Y N 360 
URC N3   N Y N 361 
URC O11  O N N 362 
URC C4   C Y N 363 
URC C5   C Y N 364 
URC N9   N Y N 365 
URC O13  O N N 366 
URC N7   N Y N 367 
URC C8   C Y N 368 
URC O24  O N N 369 
URC HN1  H N N 370 
URC HN3  H N N 371 
URC HN9  H N N 372 
URC HN7  H N N 373 
VAL N    N N N 374 
VAL CA   C N S 375 
VAL C    C N N 376 
VAL O    O N N 377 
VAL CB   C N N 378 
VAL CG1  C N N 379 
VAL CG2  C N N 380 
VAL OXT  O N N 381 
VAL H    H N N 382 
VAL H2   H N N 383 
VAL HA   H N N 384 
VAL HB   H N N 385 
VAL HG11 H N N 386 
VAL HG12 H N N 387 
VAL HG13 H N N 388 
VAL HG21 H N N 389 
VAL HG22 H N N 390 
VAL HG23 H N N 391 
VAL HXT  H N N 392 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
GLN N   CA   sing N N 70  
GLN N   H    sing N N 71  
GLN N   H2   sing N N 72  
GLN CA  C    sing N N 73  
GLN CA  CB   sing N N 74  
GLN CA  HA   sing N N 75  
GLN C   O    doub N N 76  
GLN C   OXT  sing N N 77  
GLN CB  CG   sing N N 78  
GLN CB  HB2  sing N N 79  
GLN CB  HB3  sing N N 80  
GLN CG  CD   sing N N 81  
GLN CG  HG2  sing N N 82  
GLN CG  HG3  sing N N 83  
GLN CD  OE1  doub N N 84  
GLN CD  NE2  sing N N 85  
GLN NE2 HE21 sing N N 86  
GLN NE2 HE22 sing N N 87  
GLN OXT HXT  sing N N 88  
GLU N   CA   sing N N 89  
GLU N   H    sing N N 90  
GLU N   H2   sing N N 91  
GLU CA  C    sing N N 92  
GLU CA  CB   sing N N 93  
GLU CA  HA   sing N N 94  
GLU C   O    doub N N 95  
GLU C   OXT  sing N N 96  
GLU CB  CG   sing N N 97  
GLU CB  HB2  sing N N 98  
GLU CB  HB3  sing N N 99  
GLU CG  CD   sing N N 100 
GLU CG  HG2  sing N N 101 
GLU CG  HG3  sing N N 102 
GLU CD  OE1  doub N N 103 
GLU CD  OE2  sing N N 104 
GLU OE2 HE2  sing N N 105 
GLU OXT HXT  sing N N 106 
GLY N   CA   sing N N 107 
GLY N   H    sing N N 108 
GLY N   H2   sing N N 109 
GLY CA  C    sing N N 110 
GLY CA  HA2  sing N N 111 
GLY CA  HA3  sing N N 112 
GLY C   O    doub N N 113 
GLY C   OXT  sing N N 114 
GLY OXT HXT  sing N N 115 
HIS N   CA   sing N N 116 
HIS N   H    sing N N 117 
HIS N   H2   sing N N 118 
HIS CA  C    sing N N 119 
HIS CA  CB   sing N N 120 
HIS CA  HA   sing N N 121 
HIS C   O    doub N N 122 
HIS C   OXT  sing N N 123 
HIS CB  CG   sing N N 124 
HIS CB  HB2  sing N N 125 
HIS CB  HB3  sing N N 126 
HIS CG  ND1  sing Y N 127 
HIS CG  CD2  doub Y N 128 
HIS ND1 CE1  doub Y N 129 
HIS ND1 HD1  sing N N 130 
HIS CD2 NE2  sing Y N 131 
HIS CD2 HD2  sing N N 132 
HIS CE1 NE2  sing Y N 133 
HIS CE1 HE1  sing N N 134 
HIS NE2 HE2  sing N N 135 
HIS OXT HXT  sing N N 136 
HOH O   H1   sing N N 137 
HOH O   H2   sing N N 138 
ILE N   CA   sing N N 139 
ILE N   H    sing N N 140 
ILE N   H2   sing N N 141 
ILE CA  C    sing N N 142 
ILE CA  CB   sing N N 143 
ILE CA  HA   sing N N 144 
ILE C   O    doub N N 145 
ILE C   OXT  sing N N 146 
ILE CB  CG1  sing N N 147 
ILE CB  CG2  sing N N 148 
ILE CB  HB   sing N N 149 
ILE CG1 CD1  sing N N 150 
ILE CG1 HG12 sing N N 151 
ILE CG1 HG13 sing N N 152 
ILE CG2 HG21 sing N N 153 
ILE CG2 HG22 sing N N 154 
ILE CG2 HG23 sing N N 155 
ILE CD1 HD11 sing N N 156 
ILE CD1 HD12 sing N N 157 
ILE CD1 HD13 sing N N 158 
ILE OXT HXT  sing N N 159 
LEU N   CA   sing N N 160 
LEU N   H    sing N N 161 
LEU N   H2   sing N N 162 
LEU CA  C    sing N N 163 
LEU CA  CB   sing N N 164 
LEU CA  HA   sing N N 165 
LEU C   O    doub N N 166 
LEU C   OXT  sing N N 167 
LEU CB  CG   sing N N 168 
LEU CB  HB2  sing N N 169 
LEU CB  HB3  sing N N 170 
LEU CG  CD1  sing N N 171 
LEU CG  CD2  sing N N 172 
LEU CG  HG   sing N N 173 
LEU CD1 HD11 sing N N 174 
LEU CD1 HD12 sing N N 175 
LEU CD1 HD13 sing N N 176 
LEU CD2 HD21 sing N N 177 
LEU CD2 HD22 sing N N 178 
LEU CD2 HD23 sing N N 179 
LEU OXT HXT  sing N N 180 
LYS N   CA   sing N N 181 
LYS N   H    sing N N 182 
LYS N   H2   sing N N 183 
LYS CA  C    sing N N 184 
LYS CA  CB   sing N N 185 
LYS CA  HA   sing N N 186 
LYS C   O    doub N N 187 
LYS C   OXT  sing N N 188 
LYS CB  CG   sing N N 189 
LYS CB  HB2  sing N N 190 
LYS CB  HB3  sing N N 191 
LYS CG  CD   sing N N 192 
LYS CG  HG2  sing N N 193 
LYS CG  HG3  sing N N 194 
LYS CD  CE   sing N N 195 
LYS CD  HD2  sing N N 196 
LYS CD  HD3  sing N N 197 
LYS CE  NZ   sing N N 198 
LYS CE  HE2  sing N N 199 
LYS CE  HE3  sing N N 200 
LYS NZ  HZ1  sing N N 201 
LYS NZ  HZ2  sing N N 202 
LYS NZ  HZ3  sing N N 203 
LYS OXT HXT  sing N N 204 
MET N   CA   sing N N 205 
MET N   H    sing N N 206 
MET N   H2   sing N N 207 
MET CA  C    sing N N 208 
MET CA  CB   sing N N 209 
MET CA  HA   sing N N 210 
MET C   O    doub N N 211 
MET C   OXT  sing N N 212 
MET CB  CG   sing N N 213 
MET CB  HB2  sing N N 214 
MET CB  HB3  sing N N 215 
MET CG  SD   sing N N 216 
MET CG  HG2  sing N N 217 
MET CG  HG3  sing N N 218 
MET SD  CE   sing N N 219 
MET CE  HE1  sing N N 220 
MET CE  HE2  sing N N 221 
MET CE  HE3  sing N N 222 
MET OXT HXT  sing N N 223 
PHE N   CA   sing N N 224 
PHE N   H    sing N N 225 
PHE N   H2   sing N N 226 
PHE CA  C    sing N N 227 
PHE CA  CB   sing N N 228 
PHE CA  HA   sing N N 229 
PHE C   O    doub N N 230 
PHE C   OXT  sing N N 231 
PHE CB  CG   sing N N 232 
PHE CB  HB2  sing N N 233 
PHE CB  HB3  sing N N 234 
PHE CG  CD1  doub Y N 235 
PHE CG  CD2  sing Y N 236 
PHE CD1 CE1  sing Y N 237 
PHE CD1 HD1  sing N N 238 
PHE CD2 CE2  doub Y N 239 
PHE CD2 HD2  sing N N 240 
PHE CE1 CZ   doub Y N 241 
PHE CE1 HE1  sing N N 242 
PHE CE2 CZ   sing Y N 243 
PHE CE2 HE2  sing N N 244 
PHE CZ  HZ   sing N N 245 
PHE OXT HXT  sing N N 246 
PRO N   CA   sing N N 247 
PRO N   CD   sing N N 248 
PRO N   H    sing N N 249 
PRO CA  C    sing N N 250 
PRO CA  CB   sing N N 251 
PRO CA  HA   sing N N 252 
PRO C   O    doub N N 253 
PRO C   OXT  sing N N 254 
PRO CB  CG   sing N N 255 
PRO CB  HB2  sing N N 256 
PRO CB  HB3  sing N N 257 
PRO CG  CD   sing N N 258 
PRO CG  HG2  sing N N 259 
PRO CG  HG3  sing N N 260 
PRO CD  HD2  sing N N 261 
PRO CD  HD3  sing N N 262 
PRO OXT HXT  sing N N 263 
SER N   CA   sing N N 264 
SER N   H    sing N N 265 
SER N   H2   sing N N 266 
SER CA  C    sing N N 267 
SER CA  CB   sing N N 268 
SER CA  HA   sing N N 269 
SER C   O    doub N N 270 
SER C   OXT  sing N N 271 
SER CB  OG   sing N N 272 
SER CB  HB2  sing N N 273 
SER CB  HB3  sing N N 274 
SER OG  HG   sing N N 275 
SER OXT HXT  sing N N 276 
THR N   CA   sing N N 277 
THR N   H    sing N N 278 
THR N   H2   sing N N 279 
THR CA  C    sing N N 280 
THR CA  CB   sing N N 281 
THR CA  HA   sing N N 282 
THR C   O    doub N N 283 
THR C   OXT  sing N N 284 
THR CB  OG1  sing N N 285 
THR CB  CG2  sing N N 286 
THR CB  HB   sing N N 287 
THR OG1 HG1  sing N N 288 
THR CG2 HG21 sing N N 289 
THR CG2 HG22 sing N N 290 
THR CG2 HG23 sing N N 291 
THR OXT HXT  sing N N 292 
TRP N   CA   sing N N 293 
TRP N   H    sing N N 294 
TRP N   H2   sing N N 295 
TRP CA  C    sing N N 296 
TRP CA  CB   sing N N 297 
TRP CA  HA   sing N N 298 
TRP C   O    doub N N 299 
TRP C   OXT  sing N N 300 
TRP CB  CG   sing N N 301 
TRP CB  HB2  sing N N 302 
TRP CB  HB3  sing N N 303 
TRP CG  CD1  doub Y N 304 
TRP CG  CD2  sing Y N 305 
TRP CD1 NE1  sing Y N 306 
TRP CD1 HD1  sing N N 307 
TRP CD2 CE2  doub Y N 308 
TRP CD2 CE3  sing Y N 309 
TRP NE1 CE2  sing Y N 310 
TRP NE1 HE1  sing N N 311 
TRP CE2 CZ2  sing Y N 312 
TRP CE3 CZ3  doub Y N 313 
TRP CE3 HE3  sing N N 314 
TRP CZ2 CH2  doub Y N 315 
TRP CZ2 HZ2  sing N N 316 
TRP CZ3 CH2  sing Y N 317 
TRP CZ3 HZ3  sing N N 318 
TRP CH2 HH2  sing N N 319 
TRP OXT HXT  sing N N 320 
TYR N   CA   sing N N 321 
TYR N   H    sing N N 322 
TYR N   H2   sing N N 323 
TYR CA  C    sing N N 324 
TYR CA  CB   sing N N 325 
TYR CA  HA   sing N N 326 
TYR C   O    doub N N 327 
TYR C   OXT  sing N N 328 
TYR CB  CG   sing N N 329 
TYR CB  HB2  sing N N 330 
TYR CB  HB3  sing N N 331 
TYR CG  CD1  doub Y N 332 
TYR CG  CD2  sing Y N 333 
TYR CD1 CE1  sing Y N 334 
TYR CD1 HD1  sing N N 335 
TYR CD2 CE2  doub Y N 336 
TYR CD2 HD2  sing N N 337 
TYR CE1 CZ   doub Y N 338 
TYR CE1 HE1  sing N N 339 
TYR CE2 CZ   sing Y N 340 
TYR CE2 HE2  sing N N 341 
TYR CZ  OH   sing N N 342 
TYR OH  HH   sing N N 343 
TYR OXT HXT  sing N N 344 
URC N1  C2   sing Y N 345 
URC N1  C6   sing Y N 346 
URC N1  HN1  sing N N 347 
URC C2  N3   sing Y N 348 
URC C2  O11  doub N N 349 
URC C6  C5   sing Y N 350 
URC C6  O13  doub N N 351 
URC N3  C4   sing Y N 352 
URC N3  HN3  sing N N 353 
URC C4  C5   doub Y N 354 
URC C4  N9   sing Y N 355 
URC C5  N7   sing Y N 356 
URC N9  C8   sing Y N 357 
URC N9  HN9  sing N N 358 
URC N7  C8   sing Y N 359 
URC N7  HN7  sing N N 360 
URC C8  O24  doub N N 361 
VAL N   CA   sing N N 362 
VAL N   H    sing N N 363 
VAL N   H2   sing N N 364 
VAL CA  C    sing N N 365 
VAL CA  CB   sing N N 366 
VAL CA  HA   sing N N 367 
VAL C   O    doub N N 368 
VAL C   OXT  sing N N 369 
VAL CB  CG1  sing N N 370 
VAL CB  CG2  sing N N 371 
VAL CB  HB   sing N N 372 
VAL CG1 HG11 sing N N 373 
VAL CG1 HG12 sing N N 374 
VAL CG1 HG13 sing N N 375 
VAL CG2 HG21 sing N N 376 
VAL CG2 HG22 sing N N 377 
VAL CG2 HG23 sing N N 378 
VAL OXT HXT  sing N N 379 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Research Foundation (NRF, Korea)' 'Korea, Republic Of' RS-2023-00208153    1 
'National Research Foundation (NRF, Korea)' 'Korea, Republic Of' 2022R1I1A1A01068105 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8YLF 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 31 2 1' 
_space_group.name_Hall        
;P 31 2"
;
_space_group.IT_number        152 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    8YLK 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.015888 
_atom_sites.fract_transf_matrix[1][2]   0.009173 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.018345 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012892 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . MET A 1 6   ? -10.28358 -17.49935 5.33296  1.000 82.34345  ? 1   MET A N   1 
ATOM   2    C CA  . MET A 1 6   ? -9.55719  -17.46836 6.60138  1.000 76.92377  ? 1   MET A CA  1 
ATOM   3    C C   . MET A 1 6   ? -8.22238  -18.19566 6.51126  1.000 70.24962  ? 1   MET A C   1 
ATOM   4    O O   . MET A 1 6   ? -8.13196  -19.27615 5.92561  1.000 68.90468  ? 1   MET A O   1 
ATOM   5    C CB  . MET A 1 6   ? -10.39329 -18.08787 7.72277  1.000 78.10541  ? 1   MET A CB  1 
ATOM   6    C CG  . MET A 1 6   ? -11.36272 -17.13309 8.38903  1.000 83.56682  ? 1   MET A CG  1 
ATOM   7    S SD  . MET A 1 6   ? -11.96283 -17.79735 9.95642  1.000 86.76628  ? 1   MET A SD  1 
ATOM   8    C CE  . MET A 1 6   ? -13.05669 -16.48405 10.49327 1.000 91.33247  ? 1   MET A CE  1 
ATOM   9    N N   . ASP A 1 7   ? -7.18929  -17.60265 7.10619  1.000 64.02354  ? 2   ASP A N   1 
ATOM   10   C CA  . ASP A 1 7   ? -5.88454  -18.24004 7.15939  1.000 58.48222  ? 2   ASP A CA  1 
ATOM   11   C C   . ASP A 1 7   ? -5.86730  -19.29983 8.26115  1.000 52.94215  ? 2   ASP A C   1 
ATOM   12   O O   . ASP A 1 7   ? -6.86923  -19.55210 8.93739  1.000 52.30857  ? 2   ASP A O   1 
ATOM   13   C CB  . ASP A 1 7   ? -4.78519  -17.19842 7.37017  1.000 56.61657  ? 2   ASP A CB  1 
ATOM   14   C CG  . ASP A 1 7   ? -4.80564  -16.59567 8.76734  1.000 57.04552  ? 2   ASP A CG  1 
ATOM   15   O OD1 . ASP A 1 7   ? -5.90031  -16.47299 9.35226  1.000 59.28066  ? 2   ASP A OD1 1 
ATOM   16   O OD2 . ASP A 1 7   ? -3.72583  -16.23797 9.27904  1.000 54.67982  ? 2   ASP A OD2 1 
ATOM   17   N N   . ARG A 1 8   ? -4.70362  -19.93190 8.43745  1.000 49.60442  ? 3   ARG A N   1 
ATOM   18   C CA  . ARG A 1 8   ? -4.57231  -21.00122 9.42424  1.000 48.44929  ? 3   ARG A CA  1 
ATOM   19   C C   . ARG A 1 8   ? -4.90231  -20.51148 10.82666 1.000 46.10943  ? 3   ARG A C   1 
ATOM   20   O O   . ARG A 1 8   ? -5.59906  -21.19809 11.58191 1.000 47.56529  ? 3   ARG A O   1 
ATOM   21   C CB  . ARG A 1 8   ? -3.15583  -21.57719 9.40177  1.000 46.00345  ? 3   ARG A CB  1 
ATOM   22   C CG  . ARG A 1 8   ? -2.75718  -22.27237 8.11720  1.000 47.87114  ? 3   ARG A CG  1 
ATOM   23   C CD  . ARG A 1 8   ? -1.30305  -22.70179 8.18105  1.000 45.06776  ? 3   ARG A CD  1 
ATOM   24   N NE  . ARG A 1 8   ? -0.92052  -23.50033 7.02223  1.000 43.99880  ? 3   ARG A NE  1 
ATOM   25   C CZ  . ARG A 1 8   ? -1.06939  -24.81798 6.95155  1.000 48.64913  ? 3   ARG A CZ  1 
ATOM   26   N NH1 . ARG A 1 8   ? -1.59518  -25.48389 7.97174  1.000 46.69583  ? 3   ARG A NH1 1 
ATOM   27   N NH2 . ARG A 1 8   ? -0.70014  -25.47068 5.85868  1.000 55.39571  ? 3   ARG A NH2 1 
ATOM   28   N N   . ALA A 1 9   ? -4.41105  -19.32542 11.19155 1.000 43.38647  ? 4   ALA A N   1 
ATOM   29   C CA  . ALA A 1 9   ? -4.56128  -18.85544 12.56330 1.000 45.52340  ? 4   ALA A CA  1 
ATOM   30   C C   . ALA A 1 9   ? -6.00682  -18.48099 12.87083 1.000 48.08916  ? 4   ALA A C   1 
ATOM   31   O O   . ALA A 1 9   ? -6.52054  -18.80668 13.94885 1.000 47.27511  ? 4   ALA A O   1 
ATOM   32   C CB  . ALA A 1 9   ? -3.62523  -17.67378 12.81431 1.000 45.31385  ? 4   ALA A CB  1 
ATOM   33   N N   . ALA A 1 10  ? -6.68160  -17.79737 11.94170 1.000 45.94323  ? 5   ALA A N   1 
ATOM   34   C CA  . ALA A 1 10  ? -8.06270  -17.40281 12.19876 1.000 50.58921  ? 5   ALA A CA  1 
ATOM   35   C C   . ALA A 1 10  ? -8.98638  -18.61383 12.20408 1.000 52.82840  ? 5   ALA A C   1 
ATOM   36   O O   . ALA A 1 10  ? -9.89771  -18.70562 13.03524 1.000 55.12891  ? 5   ALA A O   1 
ATOM   37   C CB  . ALA A 1 10  ? -8.51903  -16.37435 11.16674 1.000 54.91636  ? 5   ALA A CB  1 
ATOM   38   N N   . HIS A 1 11  ? -8.76292  -19.55593 11.28781 1.000 53.19430  ? 6   HIS A N   1 
ATOM   39   C CA  . HIS A 1 11  ? -9.55241  -20.78124 11.28334 1.000 54.84659  ? 6   HIS A CA  1 
ATOM   40   C C   . HIS A 1 11  ? -9.35169  -21.56317 12.57365 1.000 52.36780  ? 6   HIS A C   1 
ATOM   41   O O   . HIS A 1 11  ? -10.30758 -22.12084 13.12670 1.000 53.36253  ? 6   HIS A O   1 
ATOM   42   C CB  . HIS A 1 11  ? -9.18062  -21.63410 10.07126 1.000 55.66338  ? 6   HIS A CB  1 
ATOM   43   C CG  . HIS A 1 11  ? -9.93345  -22.92371 9.98514  1.000 58.56395  ? 6   HIS A CG  1 
ATOM   44   N ND1 . HIS A 1 11  ? -11.31025 -22.98115 9.94754  1.000 63.19854  ? 6   HIS A ND1 1 
ATOM   45   C CD2 . HIS A 1 11  ? -9.50121  -24.20565 9.92903  1.000 57.88050  ? 6   HIS A CD2 1 
ATOM   46   C CE1 . HIS A 1 11  ? -11.69382 -24.24330 9.87187  1.000 64.71558  ? 6   HIS A CE1 1 
ATOM   47   N NE2 . HIS A 1 11  ? -10.61539 -25.00640 9.85732  1.000 61.73939  ? 6   HIS A NE2 1 
ATOM   48   N N   . ALA A 1 12  ? -8.11411  -21.60563 13.07301 1.000 48.47435  ? 7   ALA A N   1 
ATOM   49   C CA  . ALA A 1 12  ? -7.83677  -22.31470 14.31773 1.000 48.49932  ? 7   ALA A CA  1 
ATOM   50   C C   . ALA A 1 12  ? -8.55469  -21.66153 15.49459 1.000 51.00457  ? 7   ALA A C   1 
ATOM   51   O O   . ALA A 1 12  ? -9.19960  -22.34538 16.29718 1.000 53.43069  ? 7   ALA A O   1 
ATOM   52   C CB  . ALA A 1 12  ? -6.32902  -22.36854 14.56336 1.000 44.54131  ? 7   ALA A CB  1 
ATOM   53   N N   . VAL A 1 13  ? -8.45304  -20.33422 15.61107 1.000 50.41821  ? 8   VAL A N   1 
ATOM   54   C CA  . VAL A 1 13  ? -9.13702  -19.62072 16.68644 1.000 54.17646  ? 8   VAL A CA  1 
ATOM   55   C C   . VAL A 1 13  ? -10.64404 -19.80360 16.57193 1.000 57.13609  ? 8   VAL A C   1 
ATOM   56   O O   . VAL A 1 13  ? -11.34594 -19.95965 17.57950 1.000 61.01863  ? 8   VAL A O   1 
ATOM   57   C CB  . VAL A 1 13  ? -8.73799  -18.13243 16.67707 1.000 55.18828  ? 8   VAL A CB  1 
ATOM   58   C CG1 . VAL A 1 13  ? -9.78273  -17.28641 17.39558 1.000 60.37028  ? 8   VAL A CG1 1 
ATOM   59   C CG2 . VAL A 1 13  ? -7.38295  -17.95316 17.33429 1.000 52.12667  ? 8   VAL A CG2 1 
ATOM   60   N N   . GLU A 1 14  ? -11.16269 -19.79841 15.34410 1.000 56.82261  ? 9   GLU A N   1 
ATOM   61   C CA  . GLU A 1 14  ? -12.58471 -20.04856 15.13904 1.000 59.07881  ? 9   GLU A CA  1 
ATOM   62   C C   . GLU A 1 14  ? -12.98744 -21.41229 15.68481 1.000 57.26520  ? 9   GLU A C   1 
ATOM   63   O O   . GLU A 1 14  ? -14.05136 -21.55516 16.29764 1.000 57.67865  ? 9   GLU A O   1 
ATOM   64   C CB  . GLU A 1 14  ? -12.92334 -19.94746 13.65089 1.000 62.12580  ? 9   GLU A CB  1 
ATOM   65   C CG  . GLU A 1 14  ? -14.39633 -20.12613 13.33029 1.000 68.97764  ? 9   GLU A CG  1 
ATOM   66   C CD  . GLU A 1 14  ? -15.19932 -18.86645 13.58104 1.000 76.51893  ? 9   GLU A CD  1 
ATOM   67   O OE1 . GLU A 1 14  ? -14.58189 -17.78678 13.69061 1.000 76.47291  ? 9   GLU A OE1 1 
ATOM   68   O OE2 . GLU A 1 14  ? -16.44365 -18.95354 13.66560 1.000 81.82429  ? 9   GLU A OE2 1 
ATOM   69   N N   . GLN A 1 15  ? -12.14870 -22.42826 15.47391 1.000 54.14066  ? 10  GLN A N   1 
ATOM   70   C CA  . GLN A 1 15  ? -12.48685 -23.76446 15.94898 1.000 52.35114  ? 10  GLN A CA  1 
ATOM   71   C C   . GLN A 1 15  ? -12.42719 -23.83982 17.46860 1.000 57.24005  ? 10  GLN A C   1 
ATOM   72   O O   . GLN A 1 15  ? -13.24907 -24.52194 18.09293 1.000 58.75689  ? 10  GLN A O   1 
ATOM   73   C CB  . GLN A 1 15  ? -11.55453 -24.79872 15.31845 1.000 51.34905  ? 10  GLN A CB  1 
ATOM   74   C CG  . GLN A 1 15  ? -11.80739 -25.03870 13.83596 1.000 53.08284  ? 10  GLN A CG  1 
ATOM   75   C CD  . GLN A 1 15  ? -10.96383 -26.16711 13.27908 1.000 53.01430  ? 10  GLN A CD  1 
ATOM   76   O OE1 . GLN A 1 15  ? -9.79723  -26.32737 13.64223 1.000 52.92941  ? 10  GLN A OE1 1 
ATOM   77   N NE2 . GLN A 1 15  ? -11.55405 -26.96405 12.40107 1.000 54.05825  ? 10  GLN A NE2 1 
ATOM   78   N N   . TRP A 1 16  ? -11.46736 -23.13790 18.07903 1.000 49.35610  ? 11  TRP A N   1 
ATOM   79   C CA  . TRP A 1 16  ? -11.32603 -23.17025 19.53152 1.000 55.59161  ? 11  TRP A CA  1 
ATOM   80   C C   . TRP A 1 16  ? -12.52894 -22.54095 20.22064 1.000 60.78571  ? 11  TRP A C   1 
ATOM   81   O O   . TRP A 1 16  ? -13.04705 -23.08656 21.20128 1.000 64.75888  ? 11  TRP A O   1 
ATOM   82   C CB  . TRP A 1 16  ? -10.03837 -22.46477 19.95364 1.000 52.64128  ? 11  TRP A CB  1 
ATOM   83   C CG  . TRP A 1 16  ? -8.82770  -23.33969 19.88669 1.000 48.14830  ? 11  TRP A CG  1 
ATOM   84   C CD1 . TRP A 1 16  ? -7.70573  -23.12678 19.15017 1.000 47.88232  ? 11  TRP A CD1 1 
ATOM   85   C CD2 . TRP A 1 16  ? -8.62302  -24.57409 20.58562 1.000 48.79272  ? 11  TRP A CD2 1 
ATOM   86   N NE1 . TRP A 1 16  ? -6.80739  -24.14929 19.34802 1.000 48.34919  ? 11  TRP A NE1 1 
ATOM   87   C CE2 . TRP A 1 16  ? -7.34876  -25.05048 20.22655 1.000 46.86491  ? 11  TRP A CE2 1 
ATOM   88   C CE3 . TRP A 1 16  ? -9.39272  -25.31886 21.48640 1.000 54.49626  ? 11  TRP A CE3 1 
ATOM   89   C CZ2 . TRP A 1 16  ? -6.82655  -26.24028 20.72949 1.000 48.11127  ? 11  TRP A CZ2 1 
ATOM   90   C CZ3 . TRP A 1 16  ? -8.87184  -26.50040 21.98560 1.000 55.28010  ? 11  TRP A CZ3 1 
ATOM   91   C CH2 . TRP A 1 16  ? -7.60054  -26.94852 21.60564 1.000 51.83687  ? 11  TRP A CH2 1 
ATOM   92   N N   . ARG A 1 17  ? -12.98236 -21.38426 19.72874 1.000 62.91686  ? 12  ARG A N   1 
ATOM   93   C CA  . ARG A 1 17  ? -14.15141 -20.74124 20.32122 1.000 67.98868  ? 12  ARG A CA  1 
ATOM   94   C C   . ARG A 1 17  ? -15.37167 -21.65087 20.27740 1.000 70.31070  ? 12  ARG A C   1 
ATOM   95   O O   . ARG A 1 17  ? -16.25808 -21.54444 21.13363 1.000 73.49690  ? 12  ARG A O   1 
ATOM   96   C CB  . ARG A 1 17  ? -14.43606 -19.41394 19.61491 1.000 73.15061  ? 12  ARG A CB  1 
ATOM   97   C CG  . ARG A 1 17  ? -13.50199 -18.29445 20.05199 1.000 76.98075  ? 12  ARG A CG  1 
ATOM   98   C CD  . ARG A 1 17  ? -13.58845 -17.06670 19.15703 1.000 82.29187  ? 12  ARG A CD  1 
ATOM   99   N NE  . ARG A 1 17  ? -12.63604 -16.04480 19.58583 1.000 84.91588  ? 12  ARG A NE  1 
ATOM   100  C CZ  . ARG A 1 17  ? -12.34640 -14.94548 18.89655 1.000 86.86515  ? 12  ARG A CZ  1 
ATOM   101  N NH1 . ARG A 1 17  ? -12.93404 -14.71232 17.73100 1.000 86.94315  ? 12  ARG A NH1 1 
ATOM   102  N NH2 . ARG A 1 17  ? -11.46106 -14.07975 19.37358 1.000 87.52439  ? 12  ARG A NH2 1 
ATOM   103  N N   . SER A 1 18  ? -15.42252 -22.56551 19.30822 1.000 68.46652  ? 13  SER A N   1 
ATOM   104  C CA  . SER A 1 18  ? -16.52243 -23.51978 19.23396 1.000 71.35893  ? 13  SER A CA  1 
ATOM   105  C C   . SER A 1 18  ? -16.30732 -24.71285 20.16301 1.000 73.08018  ? 13  SER A C   1 
ATOM   106  O O   . SER A 1 18  ? -17.25731 -25.18347 20.79911 1.000 77.33443  ? 13  SER A O   1 
ATOM   107  C CB  . SER A 1 18  ? -16.70122 -23.99293 17.79143 1.000 69.68811  ? 13  SER A CB  1 
ATOM   108  O OG  . SER A 1 18  ? -17.51802 -25.14708 17.73169 1.000 70.45046  ? 13  SER A OG  1 
ATOM   109  N N   . GLU A 1 19  ? -15.07262 -25.21306 20.26027 1.000 68.76515  ? 14  GLU A N   1 
ATOM   110  C CA  . GLU A 1 19  ? -14.80139 -26.43098 21.01872 1.000 65.39440  ? 14  GLU A CA  1 
ATOM   111  C C   . GLU A 1 19  ? -14.48277 -26.17550 22.48935 1.000 66.22846  ? 14  GLU A C   1 
ATOM   112  O O   . GLU A 1 19  ? -14.82077 -27.00936 23.33890 1.000 67.72781  ? 14  GLU A O   1 
ATOM   113  C CB  . GLU A 1 19  ? -13.64937 -27.20899 20.37149 1.000 59.07254  ? 14  GLU A CB  1 
ATOM   114  C CG  . GLU A 1 19  ? -14.05137 -27.98379 19.12713 1.000 60.85028  ? 14  GLU A CG  1 
ATOM   115  C CD  . GLU A 1 19  ? -14.93472 -29.17685 19.44699 1.000 64.67436  ? 14  GLU A CD  1 
ATOM   116  O OE1 . GLU A 1 19  ? -14.73487 -29.79587 20.51510 1.000 63.06921  ? 14  GLU A OE1 1 
ATOM   117  O OE2 . GLU A 1 19  ? -15.82872 -29.49329 18.63146 1.000 67.67403  ? 14  GLU A OE2 1 
ATOM   118  N N   . ARG A 1 20  ? -13.83985 -25.05515 22.81429 1.000 65.73082  ? 15  ARG A N   1 
ATOM   119  C CA  . ARG A 1 20  ? -13.47243 -24.71472 24.19011 1.000 68.13374  ? 15  ARG A CA  1 
ATOM   120  C C   . ARG A 1 20  ? -13.89309 -23.28014 24.48413 1.000 67.70517  ? 15  ARG A C   1 
ATOM   121  O O   . ARG A 1 20  ? -13.04919 -22.38330 24.60285 1.000 65.05711  ? 15  ARG A O   1 
ATOM   122  C CB  . ARG A 1 20  ? -11.97104 -24.89712 24.42037 1.000 67.09486  ? 15  ARG A CB  1 
ATOM   123  C CG  . ARG A 1 20  ? -11.48676 -26.33740 24.37719 1.000 67.05386  ? 15  ARG A CG  1 
ATOM   124  C CD  . ARG A 1 20  ? -11.92613 -27.10771 25.60820 1.000 68.66853  ? 15  ARG A CD  1 
ATOM   125  N NE  . ARG A 1 20  ? -11.61539 -26.38123 26.83552 1.000 71.96789  ? 15  ARG A NE  1 
ATOM   126  C CZ  . ARG A 1 20  ? -10.48171 -26.50498 27.51964 1.000 69.97511  ? 15  ARG A CZ  1 
ATOM   127  N NH1 . ARG A 1 20  ? -9.53334  -27.33626 27.10482 1.000 66.18027  ? 15  ARG A NH1 1 
ATOM   128  N NH2 . ARG A 1 20  ? -10.29838 -25.79342 28.62452 1.000 72.01551  ? 15  ARG A NH2 1 
ATOM   129  N N   . PRO A 1 21  ? -15.19899 -23.02984 24.62387 1.000 71.11424  ? 16  PRO A N   1 
ATOM   130  C CA  . PRO A 1 21  ? -15.65565 -21.65383 24.87848 1.000 74.20741  ? 16  PRO A CA  1 
ATOM   131  C C   . PRO A 1 21  ? -15.19693 -21.09536 26.21321 1.000 76.87153  ? 16  PRO A C   1 
ATOM   132  O O   . PRO A 1 21  ? -15.27590 -19.87710 26.41320 1.000 80.94317  ? 16  PRO A O   1 
ATOM   133  C CB  . PRO A 1 21  ? -17.18295 -21.77511 24.81959 1.000 78.12643  ? 16  PRO A CB  1 
ATOM   134  C CG  . PRO A 1 21  ? -17.45477 -23.19179 25.18765 1.000 77.81238  ? 16  PRO A CG  1 
ATOM   135  C CD  . PRO A 1 21  ? -16.31790 -23.98775 24.60700 1.000 73.30897  ? 16  PRO A CD  1 
ATOM   136  N N   . ASP A 1 22  ? -14.72564 -21.93921 27.13257 1.000 76.21011  ? 17  ASP A N   1 
ATOM   137  C CA  . ASP A 1 22  ? -14.13797 -21.45390 28.37471 1.000 78.02247  ? 17  ASP A CA  1 
ATOM   138  C C   . ASP A 1 22  ? -12.79841 -20.75875 28.16150 1.000 77.49096  ? 17  ASP A C   1 
ATOM   139  O O   . ASP A 1 22  ? -12.28858 -20.13860 29.10240 1.000 78.30048  ? 17  ASP A O   1 
ATOM   140  C CB  . ASP A 1 22  ? -13.95989 -22.61365 29.35525 1.000 77.50754  ? 17  ASP A CB  1 
ATOM   141  C CG  . ASP A 1 22  ? -13.23901 -23.79319 28.73370 1.000 73.91762  ? 17  ASP A CG  1 
ATOM   142  O OD1 . ASP A 1 22  ? -13.69634 -24.27779 27.67840 1.000 72.50601  ? 17  ASP A OD1 1 
ATOM   143  O OD2 . ASP A 1 22  ? -12.20872 -24.22694 29.29095 1.000 72.45553  ? 17  ASP A OD2 1 
ATOM   144  N N   . LEU A 1 23  ? -12.22957 -20.84254 26.95934 1.000 75.20228  ? 18  LEU A N   1 
ATOM   145  C CA  . LEU A 1 23  ? -10.92073 -20.29368 26.63587 1.000 73.65905  ? 18  LEU A CA  1 
ATOM   146  C C   . LEU A 1 23  ? -11.03904 -18.93730 25.95257 1.000 73.94869  ? 18  LEU A C   1 
ATOM   147  O O   . LEU A 1 23  ? -12.02864 -18.63980 25.27997 1.000 76.01313  ? 18  LEU A O   1 
ATOM   148  C CB  . LEU A 1 23  ? -10.14558 -21.23876 25.71376 1.000 72.64831  ? 18  LEU A CB  1 
ATOM   149  C CG  . LEU A 1 23  ? -9.31268  -22.36053 26.32631 1.000 72.92268  ? 18  LEU A CG  1 
ATOM   150  C CD1 . LEU A 1 23  ? -8.51263  -23.05595 25.24034 1.000 69.02721  ? 18  LEU A CD1 1 
ATOM   151  C CD2 . LEU A 1 23  ? -8.39663  -21.80626 27.40015 1.000 75.55552  ? 18  LEU A CD2 1 
ATOM   152  N N   . ASP A 1 24  ? -9.99560  -18.12400 26.11345 1.000 73.12292  ? 19  ASP A N   1 
ATOM   153  C CA  . ASP A 1 24  ? -9.83213  -16.87372 25.37882 1.000 74.85700  ? 19  ASP A CA  1 
ATOM   154  C C   . ASP A 1 24  ? -8.67419  -17.05354 24.40572 1.000 69.55495  ? 19  ASP A C   1 
ATOM   155  O O   . ASP A 1 24  ? -7.51349  -16.78694 24.75352 1.000 67.54400  ? 19  ASP A O   1 
ATOM   156  C CB  . ASP A 1 24  ? -9.57336  -15.70584 26.33249 1.000 82.03275  ? 19  ASP A CB  1 
ATOM   157  C CG  . ASP A 1 24  ? -9.21701  -14.43027 25.60353 1.000 87.43039  ? 19  ASP A CG  1 
ATOM   158  O OD1 . ASP A 1 24  ? -9.93534  -14.07489 24.64782 1.000 90.65091  ? 19  ASP A OD1 1 
ATOM   159  O OD2 . ASP A 1 24  ? -8.22037  -13.78329 25.98574 1.000 89.33084  ? 19  ASP A OD2 1 
ATOM   160  N N   . PRO A 1 25  ? -8.93011  -17.51558 23.17835 1.000 73.70243  ? 20  PRO A N   1 
ATOM   161  C CA  . PRO A 1 25  ? -7.82572  -17.85487 22.26961 1.000 69.98244  ? 20  PRO A CA  1 
ATOM   162  C C   . PRO A 1 25  ? -7.36474  -16.69513 21.40377 1.000 64.86864  ? 20  PRO A C   1 
ATOM   163  O O   . PRO A 1 25  ? -6.72768  -16.91685 20.37095 1.000 61.28704  ? 20  PRO A O   1 
ATOM   164  C CB  . PRO A 1 25  ? -8.42822  -18.97087 21.41052 1.000 54.78027  ? 20  PRO A CB  1 
ATOM   165  C CG  . PRO A 1 25  ? -9.87895  -18.58008 21.30607 1.000 71.29629  ? 20  PRO A CG  1 
ATOM   166  C CD  . PRO A 1 25  ? -10.24081 -17.89475 22.61863 1.000 73.79540  ? 20  PRO A CD  1 
ATOM   167  N N   . SER A 1 26  ? -7.66865  -15.46101 21.81228 1.000 64.25197  ? 21  SER A N   1 
ATOM   168  C CA  . SER A 1 26  ? -7.37674  -14.30701 20.96459 1.000 66.16493  ? 21  SER A CA  1 
ATOM   169  C C   . SER A 1 26  ? -5.88774  -14.20173 20.64762 1.000 63.74728  ? 21  SER A C   1 
ATOM   170  O O   . SER A 1 26  ? -5.50745  -13.87645 19.51539 1.000 66.60913  ? 21  SER A O   1 
ATOM   171  C CB  . SER A 1 26  ? -7.88552  -13.02666 21.63086 1.000 69.30996  ? 21  SER A CB  1 
ATOM   172  O OG  . SER A 1 26  ? -7.69547  -13.06277 23.03449 1.000 73.07581  ? 21  SER A OG  1 
ATOM   173  N N   . SER A 1 27  ? -5.03059  -14.50841 21.62162 1.000 59.10386  ? 22  SER A N   1 
ATOM   174  C CA  . SER A 1 27  ? -3.59084  -14.35792 21.43733 1.000 56.59574  ? 22  SER A CA  1 
ATOM   175  C C   . SER A 1 27  ? -3.02175  -15.29998 20.38294 1.000 51.42363  ? 22  SER A C   1 
ATOM   176  O O   . SER A 1 27  ? -1.89024  -15.09174 19.93093 1.000 48.81369  ? 22  SER A O   1 
ATOM   177  C CB  . SER A 1 27  ? -2.87716  -14.59511 22.76339 1.000 59.43782  ? 22  SER A CB  1 
ATOM   178  O OG  . SER A 1 27  ? -3.07519  -15.93001 23.19090 1.000 61.78113  ? 22  SER A OG  1 
ATOM   179  N N   . MET A 1 28  ? -3.77338  -16.32636 19.97928 1.000 50.57335  ? 23  MET A N   1 
ATOM   180  C CA  . MET A 1 28  ? -3.24717  -17.29658 19.02334 1.000 49.74026  ? 23  MET A CA  1 
ATOM   181  C C   . MET A 1 28  ? -3.02563  -16.68999 17.64283 1.000 47.53467  ? 23  MET A C   1 
ATOM   182  O O   . MET A 1 28  ? -2.11612  -17.11673 16.92356 1.000 45.28803  ? 23  MET A O   1 
ATOM   183  C CB  . MET A 1 28  ? -4.19012  -18.49149 18.90709 1.000 50.28006  ? 23  MET A CB  1 
ATOM   184  C CG  . MET A 1 28  ? -4.28732  -19.35608 20.14544 1.000 51.43726  ? 23  MET A CG  1 
ATOM   185  S SD  . MET A 1 28  ? -5.49636  -20.66382 19.88525 1.000 51.33954  ? 23  MET A SD  1 
ATOM   186  C CE  . MET A 1 28  ? -5.16823  -21.73537 21.28177 1.000 54.24082  ? 23  MET A CE  1 
ATOM   187  N N   . ILE A 1 29  ? -3.84212  -15.71158 17.25032 1.000 48.79994  ? 24  ILE A N   1 
ATOM   188  C CA  . ILE A 1 29  ? -3.77632  -15.19261 15.88538 1.000 49.39617  ? 24  ILE A CA  1 
ATOM   189  C C   . ILE A 1 29  ? -2.43558  -14.51428 15.63307 1.000 48.48861  ? 24  ILE A C   1 
ATOM   190  O O   . ILE A 1 29  ? -1.72499  -14.84097 14.67619 1.000 48.38174  ? 24  ILE A O   1 
ATOM   191  C CB  . ILE A 1 29  ? -4.95217  -14.23692 15.61918 1.000 52.91162  ? 24  ILE A CB  1 
ATOM   192  C CG1 . ILE A 1 29  ? -6.26888  -15.00963 15.63226 1.000 53.98656  ? 24  ILE A CG1 1 
ATOM   193  C CG2 . ILE A 1 29  ? -4.77463  -13.52018 14.28683 1.000 52.94282  ? 24  ILE A CG2 1 
ATOM   194  C CD1 . ILE A 1 29  ? -7.48647  -14.12544 15.59458 1.000 57.70653  ? 24  ILE A CD1 1 
ATOM   195  N N   . VAL A 1 30  ? -2.06166  -13.57046 16.49781 1.000 51.22958  ? 25  VAL A N   1 
ATOM   196  C CA  . VAL A 1 30  ? -0.86827  -12.76887 16.24208 1.000 51.95530  ? 25  VAL A CA  1 
ATOM   197  C C   . VAL A 1 30  ? 0.39380   -13.62499 16.33539 1.000 48.03887  ? 25  VAL A C   1 
ATOM   198  O O   . VAL A 1 30  ? 1.29079   -13.52292 15.48868 1.000 47.77296  ? 25  VAL A O   1 
ATOM   199  C CB  . VAL A 1 30  ? -0.82661  -11.55574 17.19430 1.000 55.61705  ? 25  VAL A CB  1 
ATOM   200  C CG1 . VAL A 1 30  ? -1.06612  -11.98354 18.63679 1.000 56.63385  ? 25  VAL A CG1 1 
ATOM   201  C CG2 . VAL A 1 30  ? 0.49322   -10.80288 17.05774 1.000 54.46416  ? 25  VAL A CG2 1 
ATOM   202  N N   . LEU A 1 31  ? 0.47840   -14.50009 17.33981 1.000 41.30950  ? 26  LEU A N   1 
ATOM   203  C CA  . LEU A 1 31  ? 1.67127   -15.32772 17.48493 1.000 40.82715  ? 26  LEU A CA  1 
ATOM   204  C C   . LEU A 1 31  ? 1.69665   -16.47947 16.48433 1.000 40.24007  ? 26  LEU A C   1 
ATOM   205  O O   . LEU A 1 31  ? 2.77889   -16.91973 16.07806 1.000 38.69054  ? 26  LEU A O   1 
ATOM   206  C CB  . LEU A 1 31  ? 1.77626   -15.86877 18.91712 1.000 41.76087  ? 26  LEU A CB  1 
ATOM   207  C CG  . LEU A 1 31  ? 2.05171   -14.85496 20.03214 1.000 41.41665  ? 26  LEU A CG  1 
ATOM   208  C CD1 . LEU A 1 31  ? 2.01873   -15.53187 21.39397 1.000 40.23274  ? 26  LEU A CD1 1 
ATOM   209  C CD2 . LEU A 1 31  ? 3.38964   -14.15997 19.82429 1.000 39.43606  ? 26  LEU A CD2 1 
ATOM   210  N N   . GLY A 1 32  ? 0.53166   -16.99412 16.09116 1.000 40.34743  ? 27  GLY A N   1 
ATOM   211  C CA  . GLY A 1 32  ? 0.50519   -17.98758 15.03112 1.000 41.57205  ? 27  GLY A CA  1 
ATOM   212  C C   . GLY A 1 32  ? 0.89236   -17.39607 13.68951 1.000 40.36591  ? 27  GLY A C   1 
ATOM   213  O O   . GLY A 1 32  ? 1.62375   -18.01665 12.91377 1.000 37.09072  ? 27  GLY A O   1 
ATOM   214  N N   . ARG A 1 33  ? 0.42395   -16.17894 13.40455 1.000 42.48559  ? 28  ARG A N   1 
ATOM   215  C CA  . ARG A 1 33  ? 0.82694   -15.51513 12.17064 1.000 45.51478  ? 28  ARG A CA  1 
ATOM   216  C C   . ARG A 1 33  ? 2.28441   -15.07695 12.21604 1.000 46.04126  ? 28  ARG A C   1 
ATOM   217  O O   . ARG A 1 33  ? 2.95302   -15.05293 11.17676 1.000 45.57197  ? 28  ARG A O   1 
ATOM   218  C CB  . ARG A 1 33  ? -0.08528  -14.32317 11.89032 1.000 44.23533  ? 28  ARG A CB  1 
ATOM   219  C CG  . ARG A 1 33  ? -1.46638  -14.73557 11.43190 1.000 44.97436  ? 28  ARG A CG  1 
ATOM   220  C CD  . ARG A 1 33  ? -2.28120  -13.54836 10.96714 1.000 46.97730  ? 28  ARG A CD  1 
ATOM   221  N NE  . ARG A 1 33  ? -3.62521  -13.96832 10.59740 1.000 45.35520  ? 28  ARG A NE  1 
ATOM   222  C CZ  . ARG A 1 33  ? -4.69115  -13.18028 10.63185 1.000 46.24347  ? 28  ARG A CZ  1 
ATOM   223  N NH1 . ARG A 1 33  ? -4.57634  -11.91874 11.02079 1.000 47.25469  ? 28  ARG A NH1 1 
ATOM   224  N NH2 . ARG A 1 33  ? -5.87370  -13.65970 10.28308 1.000 48.59834  ? 28  ARG A NH2 1 
ATOM   225  N N   . LEU A 1 34  ? 2.79428   -14.73108 13.39857 1.000 42.72125  ? 29  LEU A N   1 
ATOM   226  C CA  . LEU A 1 34  ? 4.20930   -14.40043 13.52189 1.000 39.96580  ? 29  LEU A CA  1 
ATOM   227  C C   . LEU A 1 34  ? 5.07863   -15.59780 13.16291 1.000 39.83304  ? 29  LEU A C   1 
ATOM   228  O O   . LEU A 1 34  ? 6.03924   -15.47899 12.39102 1.000 39.70919  ? 29  LEU A O   1 
ATOM   229  C CB  . LEU A 1 34  ? 4.51101   -13.92281 14.94506 1.000 42.83338  ? 29  LEU A CB  1 
ATOM   230  C CG  . LEU A 1 34  ? 5.97393   -13.63471 15.29050 1.000 42.01686  ? 29  LEU A CG  1 
ATOM   231  C CD1 . LEU A 1 34  ? 6.40098   -12.30769 14.69937 1.000 45.89127  ? 29  LEU A CD1 1 
ATOM   232  C CD2 . LEU A 1 34  ? 6.18047   -13.62735 16.79158 1.000 44.97718  ? 29  LEU A CD2 1 
ATOM   233  N N   . GLN A 1 35  ? 4.75238   -16.76870 13.71313 1.000 39.12915  ? 30  GLN A N   1 
ATOM   234  C CA  . GLN A 1 35  ? 5.58479   -17.94228 13.47653 1.000 39.16099  ? 30  GLN A CA  1 
ATOM   235  C C   . GLN A 1 35  ? 5.43629   -18.44635 12.04753 1.000 36.95520  ? 30  GLN A C   1 
ATOM   236  O O   . GLN A 1 35  ? 6.42424   -18.83887 11.41582 1.000 34.63896  ? 30  GLN A O   1 
ATOM   237  C CB  . GLN A 1 35  ? 5.23923   -19.04245 14.48006 1.000 40.92981  ? 30  GLN A CB  1 
ATOM   238  C CG  . GLN A 1 35  ? 5.53448   -18.66443 15.92941 1.000 45.66652  ? 30  GLN A CG  1 
ATOM   239  C CD  . GLN A 1 35  ? 5.30235   -19.81267 16.89483 1.000 49.36235  ? 30  GLN A CD  1 
ATOM   240  O OE1 . GLN A 1 35  ? 6.20954   -20.59329 17.17720 1.000 52.57795  ? 30  GLN A OE1 1 
ATOM   241  N NE2 . GLN A 1 35  ? 4.08218   -19.91973 17.40566 1.000 49.76533  ? 30  GLN A NE2 1 
ATOM   242  N N   . GLU A 1 36  ? 4.21241   -18.44686 11.52039 1.000 38.47360  ? 31  GLU A N   1 
ATOM   243  C CA  . GLU A 1 36  ? 4.00841   -18.93547 10.16026 1.000 40.14507  ? 31  GLU A CA  1 
ATOM   244  C C   . GLU A 1 36  ? 4.67150   -18.02137 9.13683  1.000 40.42187  ? 31  GLU A C   1 
ATOM   245  O O   . GLU A 1 36  ? 5.25256   -18.49921 8.15518  1.000 43.36939  ? 31  GLU A O   1 
ATOM   246  C CB  . GLU A 1 36  ? 2.51424   -19.08100 9.87263  1.000 41.98110  ? 31  GLU A CB  1 
ATOM   247  C CG  . GLU A 1 36  ? 2.18833   -19.58327 8.46807  1.000 47.25350  ? 31  GLU A CG  1 
ATOM   248  C CD  . GLU A 1 36  ? 2.53388   -21.04897 8.25780  1.000 50.96756  ? 31  GLU A CD  1 
ATOM   249  O OE1 . GLU A 1 36  ? 3.14325   -21.67305 9.15611  1.000 51.57866  ? 31  GLU A OE1 1 
ATOM   250  O OE2 . GLU A 1 36  ? 2.18564   -21.58020 7.18463  1.000 52.71660  ? 31  GLU A OE2 1 
ATOM   251  N N   . ALA A 1 37  ? 4.59858   -16.70555 9.34643  1.000 39.96335  ? 32  ALA A N   1 
ATOM   252  C CA  . ALA A 1 37  ? 5.24610   -15.78232 8.42094  1.000 41.49298  ? 32  ALA A CA  1 
ATOM   253  C C   . ALA A 1 37  ? 6.75845   -15.94504 8.45373  1.000 40.57734  ? 32  ALA A C   1 
ATOM   254  O O   . ALA A 1 37  ? 7.40807   -15.96811 7.40153  1.000 36.65352  ? 32  ALA A O   1 
ATOM   255  C CB  . ALA A 1 37  ? 4.85348   -14.34286 8.74403  1.000 41.05061  ? 32  ALA A CB  1 
ATOM   256  N N   . ALA A 1 38  ? 7.33778   -16.07465 9.65053  1.000 35.69013  ? 33  ALA A N   1 
ATOM   257  C CA  . ALA A 1 38  ? 8.77742   -16.29132 9.73872  1.000 35.40222  ? 33  ALA A CA  1 
ATOM   258  C C   . ALA A 1 38  ? 9.18136   -17.60057 9.07389  1.000 34.86516  ? 33  ALA A C   1 
ATOM   259  O O   . ALA A 1 38  ? 10.22372  -17.67586 8.41539  1.000 37.12360  ? 33  ALA A O   1 
ATOM   260  C CB  . ALA A 1 38  ? 9.22472   -16.27759 11.19785 1.000 37.75924  ? 33  ALA A CB  1 
ATOM   261  N N   . LEU A 1 39  ? 8.36901   -18.64389 9.23405  1.000 34.56408  ? 34  LEU A N   1 
ATOM   262  C CA  . LEU A 1 39  ? 8.70619   -19.93838 8.65484  1.000 36.31529  ? 34  LEU A CA  1 
ATOM   263  C C   . LEU A 1 39  ? 8.57465   -19.91741 7.13240  1.000 39.35249  ? 34  LEU A C   1 
ATOM   264  O O   . LEU A 1 39  ? 9.46313   -20.39332 6.41614  1.000 39.77081  ? 34  LEU A O   1 
ATOM   265  C CB  . LEU A 1 39  ? 7.82015   -21.02494 9.26927  1.000 37.73848  ? 34  LEU A CB  1 
ATOM   266  C CG  . LEU A 1 39  ? 7.85760   -22.40250 8.60031  1.000 40.71157  ? 34  LEU A CG  1 
ATOM   267  C CD1 . LEU A 1 39  ? 9.24240   -23.01636 8.68230  1.000 40.10653  ? 34  LEU A CD1 1 
ATOM   268  C CD2 . LEU A 1 39  ? 6.82328   -23.33317 9.21108  1.000 42.39573  ? 34  LEU A CD2 1 
ATOM   269  N N   . VAL A 1 40  ? 7.47285   -19.36576 6.61822  1.000 39.67749  ? 35  VAL A N   1 
ATOM   270  C CA  . VAL A 1 40  ? 7.23940   -19.39325 5.17752  1.000 41.03559  ? 35  VAL A CA  1 
ATOM   271  C C   . VAL A 1 40  ? 8.25022   -18.51374 4.45243  1.000 39.92047  ? 35  VAL A C   1 
ATOM   272  O O   . VAL A 1 40  ? 8.78550   -18.89708 3.40569  1.000 42.08374  ? 35  VAL A O   1 
ATOM   273  C CB  . VAL A 1 40  ? 5.78998   -18.98116 4.85764  1.000 39.44578  ? 35  VAL A CB  1 
ATOM   274  C CG1 . VAL A 1 40  ? 5.61964   -18.72170 3.35233  1.000 43.89050  ? 35  VAL A CG1 1 
ATOM   275  C CG2 . VAL A 1 40  ? 4.82860   -20.06242 5.31130  1.000 38.73219  ? 35  VAL A CG2 1 
ATOM   276  N N   . ILE A 1 41  ? 8.53636   -17.32944 4.99641  1.000 34.46913  ? 36  ILE A N   1 
ATOM   277  C CA  . ILE A 1 41  ? 9.49298   -16.43267 4.35695  1.000 36.79197  ? 36  ILE A CA  1 
ATOM   278  C C   . ILE A 1 41  ? 10.88759  -17.04929 4.35648  1.000 38.65855  ? 36  ILE A C   1 
ATOM   279  O O   . ILE A 1 41  ? 11.57663  -17.05492 3.32888  1.000 40.41701  ? 36  ILE A O   1 
ATOM   280  C CB  . ILE A 1 41  ? 9.47408   -15.05369 5.03569  1.000 39.26195  ? 36  ILE A CB  1 
ATOM   281  C CG1 . ILE A 1 41  ? 8.15869   -14.33882 4.72840  1.000 42.42064  ? 36  ILE A CG1 1 
ATOM   282  C CG2 . ILE A 1 41  ? 10.65467  -14.21339 4.57872  1.000 39.05719  ? 36  ILE A CG2 1 
ATOM   283  C CD1 . ILE A 1 41  ? 7.99087   -13.03416 5.47891  1.000 43.22494  ? 36  ILE A CD1 1 
ATOM   284  N N   . ALA A 1 42  ? 11.31464  -17.60630 5.49659  1.000 35.43931  ? 37  ALA A N   1 
ATOM   285  C CA  . ALA A 1 42  ? 12.60769  -18.28582 5.53994  1.000 36.30927  ? 37  ALA A CA  1 
ATOM   286  C C   . ALA A 1 42  ? 12.65932  -19.44006 4.54538  1.000 41.23509  ? 37  ALA A C   1 
ATOM   287  O O   . ALA A 1 42  ? 13.61501  -19.56501 3.77138  1.000 41.93235  ? 37  ALA A O   1 
ATOM   288  C CB  . ALA A 1 42  ? 12.89890  -18.79397 6.95008  1.000 33.78178  ? 37  ALA A CB  1 
ATOM   289  N N   . ARG A 1 43  ? 11.62381  -20.28412 4.53843  1.000 41.89147  ? 38  ARG A N   1 
ATOM   290  C CA  . ARG A 1 43  ? 11.66852  -21.52108 3.76223  1.000 40.15066  ? 38  ARG A CA  1 
ATOM   291  C C   . ARG A 1 43  ? 11.53703  -21.25342 2.26483  1.000 43.53681  ? 38  ARG A C   1 
ATOM   292  O O   . ARG A 1 43  ? 12.28190  -21.82012 1.45267  1.000 40.51061  ? 38  ARG A O   1 
ATOM   293  C CB  . ARG A 1 43  ? 10.56128  -22.46406 4.23348  1.000 41.61215  ? 38  ARG A CB  1 
ATOM   294  C CG  . ARG A 1 43  ? 10.56162  -23.81815 3.55926  1.000 45.35628  ? 38  ARG A CG  1 
ATOM   295  C CD  . ARG A 1 43  ? 9.29893   -24.57085 3.91481  1.000 48.35052  ? 38  ARG A CD  1 
ATOM   296  N NE  . ARG A 1 43  ? 8.13514   -23.94624 3.30055  1.000 53.73015  ? 38  ARG A NE  1 
ATOM   297  C CZ  . ARG A 1 43  ? 6.96760   -23.77455 3.91034  1.000 59.58478  ? 38  ARG A CZ  1 
ATOM   298  N NH1 . ARG A 1 43  ? 6.80267   -24.17450 5.16579  1.000 56.12783  ? 38  ARG A NH1 1 
ATOM   299  N NH2 . ARG A 1 43  ? 5.96617   -23.19155 3.26400  1.000 64.84623  ? 38  ARG A NH2 1 
ATOM   300  N N   . ASP A 1 44  ? 10.58158  -20.40525 1.87946  1.000 45.20155  ? 39  ASP A N   1 
ATOM   301  C CA  . ASP A 1 44  ? 10.21749  -20.22522 0.48021  1.000 50.75229  ? 39  ASP A CA  1 
ATOM   302  C C   . ASP A 1 44  ? 10.83460  -18.99039 -0.16631 1.000 49.16650  ? 39  ASP A C   1 
ATOM   303  O O   . ASP A 1 44  ? 10.75768  -18.85819 -1.39114 1.000 52.43700  ? 39  ASP A O   1 
ATOM   304  C CB  . ASP A 1 44  ? 8.68783   -20.15556 0.33505  1.000 53.96534  ? 39  ASP A CB  1 
ATOM   305  C CG  . ASP A 1 44  ? 8.00364   -21.45498 0.72255  1.000 56.08864  ? 39  ASP A CG  1 
ATOM   306  O OD1 . ASP A 1 44  ? 8.71372   -22.44330 1.00908  1.000 55.72825  ? 39  ASP A OD1 1 
ATOM   307  O OD2 . ASP A 1 44  ? 6.75540   -21.48850 0.73895  1.000 58.18894  ? 39  ASP A OD2 1 
ATOM   308  N N   . ARG A 1 45  ? 11.43258  -18.08282 0.60706  1.000 45.53627  ? 40  ARG A N   1 
ATOM   309  C CA  . ARG A 1 45  ? 11.94963  -16.83942 0.04368  1.000 44.94790  ? 40  ARG A CA  1 
ATOM   310  C C   . ARG A 1 45  ? 13.43354  -16.64866 0.32199  1.000 43.79614  ? 40  ARG A C   1 
ATOM   311  O O   . ARG A 1 45  ? 14.21977  -16.54756 -0.62527 1.000 40.18416  ? 40  ARG A O   1 
ATOM   312  C CB  . ARG A 1 45  ? 11.14524  -15.64074 0.57071  1.000 44.23645  ? 40  ARG A CB  1 
ATOM   313  C CG  . ARG A 1 45  ? 9.64103   -15.73847 0.35513  1.000 45.98081  ? 40  ARG A CG  1 
ATOM   314  C CD  . ARG A 1 45  ? 9.29596   -15.98312 -1.10554 1.000 48.51917  ? 40  ARG A CD  1 
ATOM   315  N NE  . ARG A 1 45  ? 9.68742   -14.87016 -1.96920 1.000 52.83163  ? 40  ARG A NE  1 
ATOM   316  C CZ  . ARG A 1 45  ? 8.88916   -13.85341 -2.28730 1.000 59.06890  ? 40  ARG A CZ  1 
ATOM   317  N NH1 . ARG A 1 45  ? 7.65421   -13.79790 -1.80767 1.000 61.68269  ? 40  ARG A NH1 1 
ATOM   318  N NH2 . ARG A 1 45  ? 9.32316   -12.88690 -3.08378 1.000 58.99326  ? 40  ARG A NH2 1 
ATOM   319  N N   . LEU A 1 46  ? 13.84294  -16.59783 1.59196  1.000 37.18492  ? 41  LEU A N   1 
ATOM   320  C CA  . LEU A 1 46  ? 15.20768  -16.20672 1.92584  1.000 39.21892  ? 41  LEU A CA  1 
ATOM   321  C C   . LEU A 1 46  ? 16.20121  -17.33422 1.67274  1.000 39.66673  ? 41  LEU A C   1 
ATOM   322  O O   . LEU A 1 46  ? 17.21470  -17.13721 0.99297  1.000 40.95898  ? 41  LEU A O   1 
ATOM   323  C CB  . LEU A 1 46  ? 15.27891  -15.75625 3.38884  1.000 37.92516  ? 41  LEU A CB  1 
ATOM   324  C CG  . LEU A 1 46  ? 14.37906  -14.58400 3.77632  1.000 40.31644  ? 41  LEU A CG  1 
ATOM   325  C CD1 . LEU A 1 46  ? 14.58452  -14.21275 5.23666  1.000 42.56703  ? 41  LEU A CD1 1 
ATOM   326  C CD2 . LEU A 1 46  ? 14.65610  -13.40355 2.86813  1.000 42.37354  ? 41  LEU A CD2 1 
ATOM   327  N N   . ASN A 1 47  ? 15.92997  -18.51547 2.21220  1.000 35.51033  ? 42  ASN A N   1 
ATOM   328  C CA  . ASN A 1 47  ? 16.88324  -19.61626 2.17622  1.000 37.59846  ? 42  ASN A CA  1 
ATOM   329  C C   . ASN A 1 47  ? 17.15248  -20.14709 0.76603  1.000 39.94939  ? 42  ASN A C   1 
ATOM   330  O O   . ASN A 1 47  ? 18.29705  -20.52703 0.48508  1.000 41.19116  ? 42  ASN A O   1 
ATOM   331  C CB  . ASN A 1 47  ? 16.41776  -20.74719 3.09814  1.000 39.36883  ? 42  ASN A CB  1 
ATOM   332  C CG  . ASN A 1 47  ? 16.56766  -20.39178 4.57856  1.000 42.49331  ? 42  ASN A CG  1 
ATOM   333  O OD1 . ASN A 1 47  ? 17.22334  -19.41051 4.93214  1.000 41.10776  ? 42  ASN A OD1 1 
ATOM   334  N ND2 . ASN A 1 47  ? 15.96965  -21.19886 5.44510  1.000 43.23531  ? 42  ASN A ND2 1 
ATOM   335  N N   . PRO A 1 48  ? 16.16659  -20.21922 -0.14350 1.000 40.28663  ? 43  PRO A N   1 
ATOM   336  C CA  . PRO A 1 48  ? 16.51978  -20.60290 -1.52530 1.000 42.06512  ? 43  PRO A CA  1 
ATOM   337  C C   . PRO A 1 48  ? 17.51813  -19.65233 -2.16125 1.000 44.19863  ? 43  PRO A C   1 
ATOM   338  O O   . PRO A 1 48  ? 18.40570  -20.09849 -2.89802 1.000 49.17610  ? 43  PRO A O   1 
ATOM   339  C CB  . PRO A 1 48  ? 15.16765  -20.59437 -2.25319 1.000 42.12627  ? 43  PRO A CB  1 
ATOM   340  C CG  . PRO A 1 48  ? 14.18066  -20.89591 -1.19011 1.000 42.99831  ? 43  PRO A CG  1 
ATOM   341  C CD  . PRO A 1 48  ? 14.70182  -20.18148 0.03882  1.000 39.46306  ? 43  PRO A CD  1 
ATOM   342  N N   . LEU A 1 49  ? 17.40958  -18.34938 -1.88646 1.000 40.95948  ? 44  LEU A N   1 
ATOM   343  C CA  . LEU A 1 49  ? 18.40324  -17.40845 -2.38974 1.000 42.37390  ? 44  LEU A CA  1 
ATOM   344  C C   . LEU A 1 49  ? 19.77988  -17.70015 -1.80566 1.000 44.36471  ? 44  LEU A C   1 
ATOM   345  O O   . LEU A 1 49  ? 20.77432  -17.75937 -2.53591 1.000 45.95125  ? 44  LEU A O   1 
ATOM   346  C CB  . LEU A 1 49  ? 17.98364  -15.97353 -2.08030 1.000 45.07447  ? 44  LEU A CB  1 
ATOM   347  C CG  . LEU A 1 49  ? 18.94959  -14.95973 -2.69907 1.000 51.03492  ? 44  LEU A CG  1 
ATOM   348  C CD1 . LEU A 1 49  ? 18.18446  -13.91189 -3.47949 1.000 55.56454  ? 44  LEU A CD1 1 
ATOM   349  C CD2 . LEU A 1 49  ? 19.85357  -14.31096 -1.65251 1.000 49.67411  ? 44  LEU A CD2 1 
ATOM   350  N N   . PHE A 1 50  ? 19.86212  -17.87190 -0.48248 1.000 44.75374  ? 45  PHE A N   1 
ATOM   351  C CA  . PHE A 1 50  ? 21.13387  -18.26302 0.11638  1.000 42.07339  ? 45  PHE A CA  1 
ATOM   352  C C   . PHE A 1 50  ? 21.65195  -19.55042 -0.50993 1.000 41.64299  ? 45  PHE A C   1 
ATOM   353  O O   . PHE A 1 50  ? 22.86265  -19.71689 -0.70121 1.000 41.47848  ? 45  PHE A O   1 
ATOM   354  C CB  . PHE A 1 50  ? 20.98510  -18.43748 1.62850  1.000 42.10564  ? 45  PHE A CB  1 
ATOM   355  C CG  . PHE A 1 50  ? 20.49867  -17.20852 2.34348  1.000 40.92853  ? 45  PHE A CG  1 
ATOM   356  C CD1 . PHE A 1 50  ? 20.85352  -15.94433 1.90851  1.000 40.96539  ? 45  PHE A CD1 1 
ATOM   357  C CD2 . PHE A 1 50  ? 19.67685  -17.32447 3.45519  1.000 36.34813  ? 45  PHE A CD2 1 
ATOM   358  C CE1 . PHE A 1 50  ? 20.40053  -14.81736 2.57101  1.000 40.47695  ? 45  PHE A CE1 1 
ATOM   359  C CE2 . PHE A 1 50  ? 19.22099  -16.20670 4.11799  1.000 36.70922  ? 45  PHE A CE2 1 
ATOM   360  C CZ  . PHE A 1 50  ? 19.58195  -14.94894 3.67518  1.000 38.79624  ? 45  PHE A CZ  1 
ATOM   361  N N   . ALA A 1 51  ? 20.74333  -20.46963 -0.84263 1.000 42.33444  ? 46  ALA A N   1 
ATOM   362  C CA  . ALA A 1 51  ? 21.14328  -21.74975 -1.41317 1.000 49.05287  ? 46  ALA A CA  1 
ATOM   363  C C   . ALA A 1 51  ? 21.73624  -21.59079 -2.80677 1.000 50.88978  ? 46  ALA A C   1 
ATOM   364  O O   . ALA A 1 51  ? 22.62463  -22.36127 -3.18580 1.000 52.68845  ? 46  ALA A O   1 
ATOM   365  C CB  . ALA A 1 51  ? 19.94928  -22.70210 -1.45204 1.000 50.58744  ? 46  ALA A CB  1 
ATOM   366  N N   . ARG A 1 52  ? 21.26370  -20.60801 -3.58149 1.000 52.08191  ? 47  ARG A N   1 
ATOM   367  C CA  . ARG A 1 52  ? 21.87133  -20.34751 -4.88406 1.000 56.42349  ? 47  ARG A CA  1 
ATOM   368  C C   . ARG A 1 52  ? 23.34492  -20.00210 -4.73911 1.000 53.29274  ? 47  ARG A C   1 
ATOM   369  O O   . ARG A 1 52  ? 24.14137  -20.28479 -5.64104 1.000 53.18888  ? 47  ARG A O   1 
ATOM   370  C CB  . ARG A 1 52  ? 21.14185  -19.21227 -5.61068 1.000 61.03497  ? 47  ARG A CB  1 
ATOM   371  C CG  . ARG A 1 52  ? 19.65602  -19.43816 -5.83390 1.000 65.74248  ? 47  ARG A CG  1 
ATOM   372  C CD  . ARG A 1 52  ? 19.10148  -18.55795 -6.95692 1.000 73.43335  ? 47  ARG A CD  1 
ATOM   373  N NE  . ARG A 1 52  ? 19.22323  -17.11636 -6.71632 1.000 76.28867  ? 47  ARG A NE  1 
ATOM   374  C CZ  . ARG A 1 52  ? 19.95048  -16.28554 -7.46568 1.000 78.21939  ? 47  ARG A CZ  1 
ATOM   375  N NH1 . ARG A 1 52  ? 20.63437  -16.74665 -8.50618 1.000 80.12658  ? 47  ARG A NH1 1 
ATOM   376  N NH2 . ARG A 1 52  ? 19.99260  -14.98895 -7.18070 1.000 76.90062  ? 47  ARG A NH2 1 
ATOM   377  N N   . TYR A 1 53  ? 23.72476  -19.40131 -3.61127 1.000 53.94073  ? 48  TYR A N   1 
ATOM   378  C CA  . TYR A 1 53  ? 25.10524  -19.03027 -3.33613 1.000 52.76016  ? 48  TYR A CA  1 
ATOM   379  C C   . TYR A 1 53  ? 25.85824  -20.10891 -2.57262 1.000 51.80861  ? 48  TYR A C   1 
ATOM   380  O O   . TYR A 1 53  ? 26.99294  -19.87176 -2.14722 1.000 51.21067  ? 48  TYR A O   1 
ATOM   381  C CB  . TYR A 1 53  ? 25.15115  -17.70484 -2.56358 1.000 50.23313  ? 48  TYR A CB  1 
ATOM   382  C CG  . TYR A 1 53  ? 24.78605  -16.51630 -3.42083 1.000 52.74647  ? 48  TYR A CG  1 
ATOM   383  C CD1 . TYR A 1 53  ? 23.46012  -16.14255 -3.59775 1.000 56.15237  ? 48  TYR A CD1 1 
ATOM   384  C CD2 . TYR A 1 53  ? 25.76534  -15.78133 -4.07202 1.000 52.99256  ? 48  TYR A CD2 1 
ATOM   385  C CE1 . TYR A 1 53  ? 23.12088  -15.06424 -4.39625 1.000 58.28274  ? 48  TYR A CE1 1 
ATOM   386  C CE2 . TYR A 1 53  ? 25.43722  -14.69998 -4.86764 1.000 56.49028  ? 48  TYR A CE2 1 
ATOM   387  C CZ  . TYR A 1 53  ? 24.11453  -14.34727 -5.02822 1.000 59.67661  ? 48  TYR A CZ  1 
ATOM   388  O OH  . TYR A 1 53  ? 23.78835  -13.27133 -5.82254 1.000 64.66929  ? 48  TYR A OH  1 
ATOM   389  N N   . GLY A 1 54  ? 25.25803  -21.28463 -2.39991 1.000 53.05501  ? 49  GLY A N   1 
ATOM   390  C CA  . GLY A 1 54  ? 25.88180  -22.33731 -1.62610 1.000 54.52027  ? 49  GLY A CA  1 
ATOM   391  C C   . GLY A 1 54  ? 25.89134  -22.10656 -0.13228 1.000 53.13274  ? 49  GLY A C   1 
ATOM   392  O O   . GLY A 1 54  ? 26.69239  -22.72408 0.57196  1.000 55.31863  ? 49  GLY A O   1 
ATOM   393  N N   . LEU A 1 55  ? 25.01993  -21.23997 0.37840  1.000 51.81705  ? 50  LEU A N   1 
ATOM   394  C CA  . LEU A 1 55  ? 25.00738  -20.88023 1.79265  1.000 49.98077  ? 50  LEU A CA  1 
ATOM   395  C C   . LEU A 1 55  ? 23.85994  -21.58809 2.50163  1.000 53.71654  ? 50  LEU A C   1 
ATOM   396  O O   . LEU A 1 55  ? 22.69677  -21.43736 2.11432  1.000 53.73203  ? 50  LEU A O   1 
ATOM   397  C CB  . LEU A 1 55  ? 24.88552  -19.36779 1.96682  1.000 47.35080  ? 50  LEU A CB  1 
ATOM   398  C CG  . LEU A 1 55  ? 26.18229  -18.58434 1.77505  1.000 48.09969  ? 50  LEU A CG  1 
ATOM   399  C CD1 . LEU A 1 55  ? 25.89653  -17.09531 1.76623  1.000 48.98282  ? 50  LEU A CD1 1 
ATOM   400  C CD2 . LEU A 1 55  ? 27.17170  -18.93821 2.87914  1.000 46.15148  ? 50  LEU A CD2 1 
ATOM   401  N N   . GLN A 1 56  ? 24.18861  -22.34766 3.54377  1.000 58.38308  ? 51  GLN A N   1 
ATOM   402  C CA  . GLN A 1 56  ? 23.18251  -23.04619 4.32236  1.000 64.67366  ? 51  GLN A CA  1 
ATOM   403  C C   . GLN A 1 56  ? 22.42598  -22.05793 5.20668  1.000 63.97411  ? 51  GLN A C   1 
ATOM   404  O O   . GLN A 1 56  ? 22.80495  -20.88787 5.32028  1.000 58.17883  ? 51  GLN A O   1 
ATOM   405  C CB  . GLN A 1 56  ? 23.83566  -24.15125 5.15340  1.000 68.85155  ? 51  GLN A CB  1 
ATOM   406  C CG  . GLN A 1 56  ? 24.18793  -25.38964 4.34390  1.000 74.20163  ? 51  GLN A CG  1 
ATOM   407  C CD  . GLN A 1 56  ? 24.95876  -26.42614 5.14510  1.000 77.98851  ? 51  GLN A CD  1 
ATOM   408  O OE1 . GLN A 1 56  ? 24.61725  -26.73044 6.28882  1.000 78.85762  ? 51  GLN A OE1 1 
ATOM   409  N NE2 . GLN A 1 56  ? 26.00936  -26.97217 4.54311  1.000 79.40877  ? 51  GLN A NE2 1 
ATOM   410  N N   . PRO A 1 57  ? 21.31808  -22.49054 5.81082  1.000 73.07346  ? 52  PRO A N   1 
ATOM   411  C CA  . PRO A 1 57  ? 20.60984  -21.61951 6.76123  1.000 73.12069  ? 52  PRO A CA  1 
ATOM   412  C C   . PRO A 1 57  ? 21.52562  -21.18081 7.89383  1.000 70.42639  ? 52  PRO A C   1 
ATOM   413  O O   . PRO A 1 57  ? 22.11154  -22.00556 8.60191  1.000 69.06776  ? 52  PRO A O   1 
ATOM   414  C CB  . PRO A 1 57  ? 19.46556  -22.50716 7.26302  1.000 76.94335  ? 52  PRO A CB  1 
ATOM   415  C CG  . PRO A 1 57  ? 19.20368  -23.44153 6.13409  1.000 77.92978  ? 52  PRO A CG  1 
ATOM   416  C CD  . PRO A 1 57  ? 20.53485  -23.69966 5.48517  1.000 75.92458  ? 52  PRO A CD  1 
ATOM   417  N N   . GLY A 1 58  ? 21.65862  -19.86315 8.04886  1.000 59.33841  ? 53  GLY A N   1 
ATOM   418  C CA  . GLY A 1 58  ? 22.46727  -19.29102 9.09676  1.000 52.97510  ? 53  GLY A CA  1 
ATOM   419  C C   . GLY A 1 58  ? 23.90241  -19.00936 8.71872  1.000 47.74072  ? 53  GLY A C   1 
ATOM   420  O O   . GLY A 1 58  ? 24.57601  -18.25754 9.43350  1.000 43.18049  ? 53  GLY A O   1 
ATOM   421  N N   . GLU A 1 59  ? 24.39825  -19.58640 7.62328  1.000 47.85421  ? 54  GLU A N   1 
ATOM   422  C CA  . GLU A 1 59  ? 25.76402  -19.29938 7.20048  1.000 42.93589  ? 54  GLU A CA  1 
ATOM   423  C C   . GLU A 1 59  ? 25.88482  -17.90689 6.59974  1.000 38.13314  ? 54  GLU A C   1 
ATOM   424  O O   . GLU A 1 59  ? 26.92538  -17.26117 6.75371  1.000 37.75314  ? 54  GLU A O   1 
ATOM   425  C CB  . GLU A 1 59  ? 26.23985  -20.36042 6.20898  1.000 42.56756  ? 54  GLU A CB  1 
ATOM   426  C CG  . GLU A 1 59  ? 26.42462  -21.73777 6.83773  1.000 44.20350  ? 54  GLU A CG  1 
ATOM   427  C CD  . GLU A 1 59  ? 26.84923  -22.79482 5.83617  1.000 50.64404  ? 54  GLU A CD  1 
ATOM   428  O OE1 . GLU A 1 59  ? 26.69796  -22.56277 4.61574  1.000 51.47374  ? 54  GLU A OE1 1 
ATOM   429  O OE2 . GLU A 1 59  ? 27.33121  -23.86233 6.27115  1.000 53.06272  ? 54  GLU A OE2 1 
ATOM   430  N N   . PHE A 1 60  ? 24.83554  -17.43438 5.92233  1.000 38.25061  ? 55  PHE A N   1 
ATOM   431  C CA  . PHE A 1 60  ? 24.80553  -16.05576 5.44113  1.000 38.08361  ? 55  PHE A CA  1 
ATOM   432  C C   . PHE A 1 60  ? 25.04234  -15.07220 6.57940  1.000 37.71228  ? 55  PHE A C   1 
ATOM   433  O O   . PHE A 1 60  ? 25.83730  -14.13264 6.44531  1.000 38.13195  ? 55  PHE A O   1 
ATOM   434  C CB  . PHE A 1 60  ? 23.46085  -15.77894 4.76587  1.000 39.10319  ? 55  PHE A CB  1 
ATOM   435  C CG  . PHE A 1 60  ? 23.30340  -14.37157 4.24928  1.000 41.18840  ? 55  PHE A CG  1 
ATOM   436  C CD1 . PHE A 1 60  ? 23.70270  -14.04182 2.95555  1.000 43.53220  ? 55  PHE A CD1 1 
ATOM   437  C CD2 . PHE A 1 60  ? 22.71903  -13.38764 5.03865  1.000 40.30327  ? 55  PHE A CD2 1 
ATOM   438  C CE1 . PHE A 1 60  ? 23.54313  -12.74913 2.46980  1.000 41.91579  ? 55  PHE A CE1 1 
ATOM   439  C CE2 . PHE A 1 60  ? 22.55731  -12.09672 4.56539  1.000 41.59339  ? 55  PHE A CE2 1 
ATOM   440  C CZ  . PHE A 1 60  ? 22.96854  -11.77420 3.27599  1.000 42.41256  ? 55  PHE A CZ  1 
ATOM   441  N N   . ASP A 1 61  ? 24.36194  -15.28006 7.71159  1.000 38.06429  ? 56  ASP A N   1 
ATOM   442  C CA  . ASP A 1 61  ? 24.48372  -14.36338 8.84152  1.000 38.36814  ? 56  ASP A CA  1 
ATOM   443  C C   . ASP A 1 61  ? 25.93456  -14.22853 9.28908  1.000 37.88840  ? 56  ASP A C   1 
ATOM   444  O O   . ASP A 1 61  ? 26.41119  -13.11761 9.54202  1.000 38.67945  ? 56  ASP A O   1 
ATOM   445  C CB  . ASP A 1 61  ? 23.59605  -14.84353 9.99352  1.000 39.46316  ? 56  ASP A CB  1 
ATOM   446  C CG  . ASP A 1 61  ? 23.32561  -13.75602 11.02952 1.000 41.50247  ? 56  ASP A CG  1 
ATOM   447  O OD1 . ASP A 1 61  ? 23.68349  -12.58108 10.78753 1.000 41.78461  ? 56  ASP A OD1 1 
ATOM   448  O OD2 . ASP A 1 61  ? 22.74461  -14.08184 12.08776 1.000 44.90970  ? 56  ASP A OD2 1 
ATOM   449  N N   . VAL A 1 62  ? 26.65829  -15.34799 9.37063  1.000 43.19181  ? 57  VAL A N   1 
ATOM   450  C CA  . VAL A 1 62  ? 28.06135  -15.30435 9.77498  1.000 37.96630  ? 57  VAL A CA  1 
ATOM   451  C C   . VAL A 1 62  ? 28.86645  -14.44642 8.80877  1.000 37.94233  ? 57  VAL A C   1 
ATOM   452  O O   . VAL A 1 62  ? 29.63313  -13.56796 9.22423  1.000 39.44659  ? 57  VAL A O   1 
ATOM   453  C CB  . VAL A 1 62  ? 28.64199  -16.72719 9.87652  1.000 38.70649  ? 57  VAL A CB  1 
ATOM   454  C CG1 . VAL A 1 62  ? 30.13082  -16.66008 10.19873 1.000 39.50960  ? 57  VAL A CG1 1 
ATOM   455  C CG2 . VAL A 1 62  ? 27.89771  -17.55544 10.92775 1.000 39.83247  ? 57  VAL A CG2 1 
ATOM   456  N N   . LEU A 1 63  ? 28.70380  -14.68829 7.50126  1.000 37.93525  ? 58  LEU A N   1 
ATOM   457  C CA  . LEU A 1 63  ? 29.43946  -13.91274 6.50515  1.000 38.83099  ? 58  LEU A CA  1 
ATOM   458  C C   . LEU A 1 63  ? 29.01402  -12.45027 6.52976  1.000 39.57939  ? 58  LEU A C   1 
ATOM   459  O O   . LEU A 1 63  ? 29.85473  -11.54371 6.48371  1.000 42.47960  ? 58  LEU A O   1 
ATOM   460  C CB  . LEU A 1 63  ? 29.23725  -14.50891 5.10727  1.000 37.76550  ? 58  LEU A CB  1 
ATOM   461  C CG  . LEU A 1 63  ? 29.66815  -15.95886 4.87681  1.000 38.31567  ? 58  LEU A CG  1 
ATOM   462  C CD1 . LEU A 1 63  ? 29.65410  -16.28846 3.38289  1.000 41.90604  ? 58  LEU A CD1 1 
ATOM   463  C CD2 . LEU A 1 63  ? 31.04391  -16.22991 5.47214  1.000 38.97480  ? 58  LEU A CD2 1 
ATOM   464  N N   . ALA A 1 64  ? 27.70528  -12.20090 6.60717  1.000 37.61716  ? 59  ALA A N   1 
ATOM   465  C CA  . ALA A 1 64  ? 27.21812  -10.82581 6.64666  1.000 41.92711  ? 59  ALA A CA  1 
ATOM   466  C C   . ALA A 1 64  ? 27.71176  -10.09527 7.89051  1.000 43.88592  ? 59  ALA A C   1 
ATOM   467  O O   . ALA A 1 64  ? 28.08529  -8.91771  7.82093  1.000 44.19356  ? 59  ALA A O   1 
ATOM   468  C CB  . ALA A 1 64  ? 25.69296  -10.81021 6.58650  1.000 39.20693  ? 59  ALA A CB  1 
ATOM   469  N N   . THR A 1 65  ? 27.72747  -10.77884 9.03817  1.000 40.39866  ? 60  THR A N   1 
ATOM   470  C CA  . THR A 1 65  ? 28.19167  -10.14388 10.26726 1.000 41.43760  ? 60  THR A CA  1 
ATOM   471  C C   . THR A 1 65  ? 29.67010  -9.78666  10.16886 1.000 43.19546  ? 60  THR A C   1 
ATOM   472  O O   . THR A 1 65  ? 30.07995  -8.67940  10.53917 1.000 43.79683  ? 60  THR A O   1 
ATOM   473  C CB  . THR A 1 65  ? 27.92679  -11.06042 11.46494 1.000 41.74162  ? 60  THR A CB  1 
ATOM   474  O OG1 . THR A 1 65  ? 26.52138  -11.32350 11.56659 1.000 40.63688  ? 60  THR A OG1 1 
ATOM   475  C CG2 . THR A 1 65  ? 28.40308  -10.41403 12.75069 1.000 43.32346  ? 60  THR A CG2 1 
ATOM   476  N N   . LEU A 1 66  ? 30.48548  -10.70907 9.64747  1.000 40.90120  ? 61  LEU A N   1 
ATOM   477  C CA  . LEU A 1 66  ? 31.90911  -10.43028 9.47174  1.000 42.25256  ? 61  LEU A CA  1 
ATOM   478  C C   . LEU A 1 66  ? 32.14145  -9.27864  8.49965  1.000 46.34690  ? 61  LEU A C   1 
ATOM   479  O O   . LEU A 1 66  ? 32.99356  -8.41432  8.74069  1.000 47.58512  ? 61  LEU A O   1 
ATOM   480  C CB  . LEU A 1 66  ? 32.63256  -11.68268 8.98259  1.000 39.32758  ? 61  LEU A CB  1 
ATOM   481  C CG  . LEU A 1 66  ? 32.80509  -12.80562 9.99563  1.000 42.45868  ? 61  LEU A CG  1 
ATOM   482  C CD1 . LEU A 1 66  ? 33.37829  -14.03809 9.31901  1.000 43.72899  ? 61  LEU A CD1 1 
ATOM   483  C CD2 . LEU A 1 66  ? 33.71089  -12.33182 11.11856 1.000 44.54944  ? 61  LEU A CD2 1 
ATOM   484  N N   . ARG A 1 67  ? 31.40411  -9.25853  7.38758  1.000 45.36593  ? 62  ARG A N   1 
ATOM   485  C CA  . ARG A 1 67  ? 31.61232  -8.22609  6.38028  1.000 47.22335  ? 62  ARG A CA  1 
ATOM   486  C C   . ARG A 1 67  ? 31.28806  -6.84551  6.93452  1.000 49.61565  ? 62  ARG A C   1 
ATOM   487  O O   . ARG A 1 67  ? 32.10567  -5.92142  6.85115  1.000 49.46871  ? 62  ARG A O   1 
ATOM   488  C CB  . ARG A 1 67  ? 30.76262  -8.52354  5.14699  1.000 45.70646  ? 62  ARG A CB  1 
ATOM   489  C CG  . ARG A 1 67  ? 30.82985  -7.44399  4.08328  1.000 50.64728  ? 62  ARG A CG  1 
ATOM   490  C CD  . ARG A 1 67  ? 32.22680  -7.31568  3.49465  1.000 52.30611  ? 62  ARG A CD  1 
ATOM   491  N NE  . ARG A 1 67  ? 32.30476  -6.22635  2.52167  1.000 55.84752  ? 62  ARG A NE  1 
ATOM   492  C CZ  . ARG A 1 67  ? 32.43780  -4.94741  2.85668  1.000 54.75301  ? 62  ARG A CZ  1 
ATOM   493  N NH1 . ARG A 1 67  ? 32.50118  -4.60124  4.13865  1.000 52.65990  ? 62  ARG A NH1 1 
ATOM   494  N NH2 . ARG A 1 67  ? 32.50117  -4.01643  1.91979  1.000 53.21129  ? 62  ARG A NH2 1 
ATOM   495  N N   . ARG A 1 68  ? 30.09792  -6.68356  7.51026  1.000 46.20266  ? 63  ARG A N   1 
ATOM   496  C CA  . ARG A 1 68  ? 29.71947  -5.34735  7.94827  1.000 48.74368  ? 63  ARG A CA  1 
ATOM   497  C C   . ARG A 1 68  ? 30.43084  -4.91536  9.22550  1.000 46.88478  ? 63  ARG A C   1 
ATOM   498  O O   . ARG A 1 68  ? 30.19873  -3.79142  9.68375  1.000 50.18449  ? 63  ARG A O   1 
ATOM   499  C CB  . ARG A 1 68  ? 28.20376  -5.25288  8.13355  1.000 50.41868  ? 63  ARG A CB  1 
ATOM   500  C CG  . ARG A 1 68  ? 27.63733  -6.16794  9.18720  1.000 47.00335  ? 63  ARG A CG  1 
ATOM   501  C CD  . ARG A 1 68  ? 26.14189  -5.95689  9.32540  1.000 48.39429  ? 63  ARG A CD  1 
ATOM   502  N NE  . ARG A 1 68  ? 25.45938  -7.17859  9.73757  1.000 47.46247  ? 63  ARG A NE  1 
ATOM   503  C CZ  . ARG A 1 68  ? 25.42167  -7.64422  10.98569 1.000 51.25190  ? 63  ARG A CZ  1 
ATOM   504  N NH1 . ARG A 1 68  ? 26.02984  -6.99391  11.97338 1.000 44.86006  ? 63  ARG A NH1 1 
ATOM   505  N NH2 . ARG A 1 68  ? 24.77182  -8.77092  11.24526 1.000 50.59563  ? 63  ARG A NH2 1 
ATOM   506  N N   . SER A 1 69  ? 31.29829  -5.74951  9.79930  1.000 43.51277  ? 64  SER A N   1 
ATOM   507  C CA  . SER A 1 69  ? 32.12897  -5.27897  10.90014 1.000 51.32068  ? 64  SER A CA  1 
ATOM   508  C C   . SER A 1 69  ? 33.26561  -4.38543  10.41985 1.000 53.38664  ? 64  SER A C   1 
ATOM   509  O O   . SER A 1 69  ? 33.80014  -3.60447  11.21235 1.000 54.45442  ? 64  SER A O   1 
ATOM   510  C CB  . SER A 1 69  ? 32.69354  -6.46198  11.69446 1.000 51.67209  ? 64  SER A CB  1 
ATOM   511  O OG  . SER A 1 69  ? 33.72119  -7.12555  10.98007 1.000 53.43882  ? 64  SER A OG  1 
ATOM   512  N N   . GLY A 1 70  ? 33.63123  -4.46918  9.14593  1.000 54.98913  ? 65  GLY A N   1 
ATOM   513  C CA  . GLY A 1 70  ? 34.68908  -3.65704  8.58832  1.000 54.63654  ? 65  GLY A CA  1 
ATOM   514  C C   . GLY A 1 70  ? 36.00699  -4.40987  8.50360  1.000 54.33706  ? 65  GLY A C   1 
ATOM   515  O O   . GLY A 1 70  ? 36.23504  -5.41087  9.18831  1.000 52.10579  ? 65  GLY A O   1 
ATOM   516  N N   . ALA A 1 71  ? 36.88402  -3.91617  7.63380  1.000 55.53654  ? 66  ALA A N   1 
ATOM   517  C CA  . ALA A 1 71  ? 38.18660  -4.54066  7.45937  1.000 57.33337  ? 66  ALA A CA  1 
ATOM   518  C C   . ALA A 1 71  ? 38.92182  -4.58097  8.79737  1.000 59.96247  ? 66  ALA A C   1 
ATOM   519  O O   . ALA A 1 71  ? 38.79926  -3.64796  9.59845  1.000 63.57839  ? 66  ALA A O   1 
ATOM   520  C CB  . ALA A 1 71  ? 39.01311  -3.77958  6.41949  1.000 59.86200  ? 66  ALA A CB  1 
ATOM   521  N N   . PRO A 1 72  ? 39.68774  -5.64711  9.08191  1.000 60.99765  ? 67  PRO A N   1 
ATOM   522  C CA  . PRO A 1 72  ? 39.96621  -6.79613  8.21335  1.000 61.54098  ? 67  PRO A CA  1 
ATOM   523  C C   . PRO A 1 72  ? 38.91537  -7.90499  8.27771  1.000 59.95515  ? 67  PRO A C   1 
ATOM   524  O O   . PRO A 1 72  ? 39.23745  -9.05148  7.97118  1.000 60.61442  ? 67  PRO A O   1 
ATOM   525  C CB  . PRO A 1 72  ? 41.30254  -7.30378  8.74981  1.000 63.06990  ? 67  PRO A CB  1 
ATOM   526  C CG  . PRO A 1 72  ? 41.22002  -7.02018  10.20472 1.000 65.44848  ? 67  PRO A CG  1 
ATOM   527  C CD  . PRO A 1 72  ? 40.43326  -5.73670  10.34948 1.000 64.37458  ? 67  PRO A CD  1 
ATOM   528  N N   . TYR A 1 73  ? 37.68886  -7.56396  8.67553  1.000 58.36444  ? 68  TYR A N   1 
ATOM   529  C CA  . TYR A 1 73  ? 36.56654  -8.50466  8.68279  1.000 57.67131  ? 68  TYR A CA  1 
ATOM   530  C C   . TYR A 1 73  ? 36.87387  -9.71909  9.55979  1.000 59.77942  ? 68  TYR A C   1 
ATOM   531  O O   . TYR A 1 73  ? 36.71069  -10.86965 9.14916  1.000 62.01012  ? 68  TYR A O   1 
ATOM   532  C CB  . TYR A 1 73  ? 36.19599  -8.92899  7.25558  1.000 55.47888  ? 68  TYR A CB  1 
ATOM   533  C CG  . TYR A 1 73  ? 36.24882  -7.79820  6.24792  1.000 56.14712  ? 68  TYR A CG  1 
ATOM   534  C CD1 . TYR A 1 73  ? 35.25281  -6.82937  6.20115  1.000 55.48413  ? 68  TYR A CD1 1 
ATOM   535  C CD2 . TYR A 1 73  ? 37.29748  -7.69843  5.34533  1.000 57.81286  ? 68  TYR A CD2 1 
ATOM   536  C CE1 . TYR A 1 73  ? 35.30390  -5.78979  5.28060  1.000 55.86376  ? 68  TYR A CE1 1 
ATOM   537  C CE2 . TYR A 1 73  ? 37.35633  -6.66601  4.42508  1.000 58.57422  ? 68  TYR A CE2 1 
ATOM   538  C CZ  . TYR A 1 73  ? 36.35908  -5.71495  4.39592  1.000 58.75700  ? 68  TYR A CZ  1 
ATOM   539  O OH  . TYR A 1 73  ? 36.42619  -4.68837  3.47615  1.000 62.54325  ? 68  TYR A OH  1 
ATOM   540  N N   . ALA A 1 74  ? 37.32006  -9.45189  10.78703 1.000 55.83797  ? 69  ALA A N   1 
ATOM   541  C CA  . ALA A 1 74  ? 37.71783  -10.49818 11.72053 1.000 58.33148  ? 69  ALA A CA  1 
ATOM   542  C C   . ALA A 1 74  ? 37.12682  -10.19919 13.09115 1.000 57.33536  ? 69  ALA A C   1 
ATOM   543  O O   . ALA A 1 74  ? 37.34221  -9.11192  13.63724 1.000 55.39460  ? 69  ALA A O   1 
ATOM   544  C CB  . ALA A 1 74  ? 39.24264  -10.60848 11.80006 1.000 62.62060  ? 69  ALA A CB  1 
ATOM   545  N N   . LEU A 1 75  ? 36.39458  -11.16658 13.64819 1.000 56.83169  ? 70  LEU A N   1 
ATOM   546  C CA  . LEU A 1 75  ? 35.73270  -11.01737 14.93799 1.000 55.19746  ? 70  LEU A CA  1 
ATOM   547  C C   . LEU A 1 75  ? 35.97938  -12.24475 15.80412 1.000 56.64515  ? 70  LEU A C   1 
ATOM   548  O O   . LEU A 1 75  ? 36.13339  -13.35976 15.29610 1.000 56.98000  ? 70  LEU A O   1 
ATOM   549  C CB  . LEU A 1 75  ? 34.21225  -10.82747 14.78218 1.000 51.85757  ? 70  LEU A CB  1 
ATOM   550  C CG  . LEU A 1 75  ? 33.65170  -9.61785  14.03575 1.000 50.11620  ? 70  LEU A CG  1 
ATOM   551  C CD1 . LEU A 1 75  ? 32.13991  -9.75429  13.88868 1.000 46.97121  ? 70  LEU A CD1 1 
ATOM   552  C CD2 . LEU A 1 75  ? 34.00578  -8.33256  14.76246 1.000 51.96148  ? 70  LEU A CD2 1 
ATOM   553  N N   . THR A 1 76  ? 36.00037  -12.03295 17.12232 1.000 56.76355  ? 71  THR A N   1 
ATOM   554  C CA  . THR A 1 76  ? 35.96940  -13.16051 18.03972 1.000 60.40024  ? 71  THR A CA  1 
ATOM   555  C C   . THR A 1 76  ? 34.63553  -13.88989 17.88613 1.000 59.16299  ? 71  THR A C   1 
ATOM   556  O O   . THR A 1 76  ? 33.64039  -13.29160 17.46429 1.000 54.01761  ? 71  THR A O   1 
ATOM   557  C CB  . THR A 1 76  ? 36.14492  -12.70206 19.48931 1.000 62.71266  ? 71  THR A CB  1 
ATOM   558  O OG1 . THR A 1 76  ? 34.96436  -12.01503 19.92331 1.000 61.89544  ? 71  THR A OG1 1 
ATOM   559  C CG2 . THR A 1 76  ? 37.34026  -11.77581 19.62036 1.000 64.25391  ? 71  THR A CG2 1 
ATOM   560  N N   . PRO A 1 77  ? 34.58038  -15.18467 18.21061 1.000 64.38565  ? 72  PRO A N   1 
ATOM   561  C CA  . PRO A 1 77  ? 33.28795  -15.88703 18.12193 1.000 61.81675  ? 72  PRO A CA  1 
ATOM   562  C C   . PRO A 1 77  ? 32.22482  -15.26953 19.01343 1.000 57.36206  ? 72  PRO A C   1 
ATOM   563  O O   . PRO A 1 77  ? 31.02707  -15.39033 18.72508 1.000 57.54031  ? 72  PRO A O   1 
ATOM   564  C CB  . PRO A 1 77  ? 33.63422  -17.32213 18.54748 1.000 64.76880  ? 72  PRO A CB  1 
ATOM   565  C CG  . PRO A 1 77  ? 35.12332  -17.43706 18.35488 1.000 67.40968  ? 72  PRO A CG  1 
ATOM   566  C CD  . PRO A 1 77  ? 35.66765  -16.07416 18.65541 1.000 67.22121  ? 72  PRO A CD  1 
ATOM   567  N N   . THR A 1 78  ? 32.63268  -14.58167 20.07599 1.000 56.09467  ? 73  THR A N   1 
ATOM   568  C CA  . THR A 1 78  ? 31.67252  -13.92732 20.95379 1.000 59.41760  ? 73  THR A CA  1 
ATOM   569  C C   . THR A 1 78  ? 31.14152  -12.64562 20.32793 1.000 58.19907  ? 73  THR A C   1 
ATOM   570  O O   . THR A 1 78  ? 29.92974  -12.40403 20.32484 1.000 56.86621  ? 73  THR A O   1 
ATOM   571  C CB  . THR A 1 78  ? 32.31839  -13.64132 22.30658 1.000 62.29108  ? 73  THR A CB  1 
ATOM   572  O OG1 . THR A 1 78  ? 32.72886  -14.87895 22.89752 1.000 65.90280  ? 73  THR A OG1 1 
ATOM   573  C CG2 . THR A 1 78  ? 31.33102  -12.94213 23.23188 1.000 61.61183  ? 73  THR A CG2 1 
ATOM   574  N N   . ALA A 1 79  ? 32.03825  -11.80516 19.80815 1.000 58.03661  ? 74  ALA A N   1 
ATOM   575  C CA  . ALA A 1 79  ? 31.59722  -10.65044 19.03527 1.000 57.77106  ? 74  ALA A CA  1 
ATOM   576  C C   . ALA A 1 79  ? 30.73570  -11.08930 17.86232 1.000 56.13986  ? 74  ALA A C   1 
ATOM   577  O O   . ALA A 1 79  ? 29.74839  -10.42672 17.52317 1.000 55.56396  ? 74  ALA A O   1 
ATOM   578  C CB  . ALA A 1 79  ? 32.80428  -9.84911  18.54453 1.000 58.15510  ? 74  ALA A CB  1 
ATOM   579  N N   . LEU A 1 80  ? 31.08974  -12.21939 17.24387 1.000 53.94299  ? 75  LEU A N   1 
ATOM   580  C CA  . LEU A 1 80  ? 30.30573  -12.74726 16.13423 1.000 52.59151  ? 75  LEU A CA  1 
ATOM   581  C C   . LEU A 1 80  ? 28.88363  -13.07771 16.57212 1.000 51.50305  ? 75  LEU A C   1 
ATOM   582  O O   . LEU A 1 80  ? 27.92264  -12.79886 15.84758 1.000 50.56835  ? 75  LEU A O   1 
ATOM   583  C CB  . LEU A 1 80  ? 31.00640  -13.97689 15.55566 1.000 53.27892  ? 75  LEU A CB  1 
ATOM   584  C CG  . LEU A 1 80  ? 30.45883  -14.64943 14.29525 1.000 52.75319  ? 75  LEU A CG  1 
ATOM   585  C CD1 . LEU A 1 80  ? 30.33362  -13.67412 13.12921 1.000 46.97421  ? 75  LEU A CD1 1 
ATOM   586  C CD2 . LEU A 1 80  ? 31.35174  -15.82474 13.91836 1.000 54.58200  ? 75  LEU A CD2 1 
ATOM   587  N N   . TYR A 1 81  ? 28.72188  -13.64483 17.76932 1.000 55.98313  ? 76  TYR A N   1 
ATOM   588  C CA  . TYR A 1 81  ? 27.37462  -13.95519 18.23493 1.000 52.24822  ? 76  TYR A CA  1 
ATOM   589  C C   . TYR A 1 81  ? 26.60189  -12.69134 18.59340 1.000 50.06744  ? 76  TYR A C   1 
ATOM   590  O O   . TYR A 1 81  ? 25.40901  -12.57967 18.28786 1.000 49.19340  ? 76  TYR A O   1 
ATOM   591  C CB  . TYR A 1 81  ? 27.41378  -14.89740 19.43409 1.000 51.82079  ? 76  TYR A CB  1 
ATOM   592  C CG  . TYR A 1 81  ? 26.03324  -15.09307 20.01097 1.000 53.63062  ? 76  TYR A CG  1 
ATOM   593  C CD1 . TYR A 1 81  ? 25.16413  -16.03057 19.47123 1.000 54.21996  ? 76  TYR A CD1 1 
ATOM   594  C CD2 . TYR A 1 81  ? 25.58095  -14.31244 21.06935 1.000 54.62988  ? 76  TYR A CD2 1 
ATOM   595  C CE1 . TYR A 1 81  ? 23.88987  -16.20067 19.98338 1.000 53.62281  ? 76  TYR A CE1 1 
ATOM   596  C CE2 . TYR A 1 81  ? 24.30962  -14.47427 21.58602 1.000 53.41074  ? 76  TYR A CE2 1 
ATOM   597  C CZ  . TYR A 1 81  ? 23.47148  -15.42159 21.04153 1.000 53.02228  ? 76  TYR A CZ  1 
ATOM   598  O OH  . TYR A 1 81  ? 22.20740  -15.58622 21.55528 1.000 56.85533  ? 76  TYR A OH  1 
ATOM   599  N N   . ASP A 1 82  ? 27.25371  -11.73957 19.26340 1.000 51.02739  ? 77  ASP A N   1 
ATOM   600  C CA  . ASP A 1 82  ? 26.55526  -10.52770 19.67664 1.000 50.44880  ? 77  ASP A CA  1 
ATOM   601  C C   . ASP A 1 82  ? 26.15013  -9.66593  18.48534 1.000 48.52113  ? 77  ASP A C   1 
ATOM   602  O O   . ASP A 1 82  ? 25.11552  -8.98967  18.53519 1.000 49.09737  ? 77  ASP A O   1 
ATOM   603  C CB  . ASP A 1 82  ? 27.42674  -9.73029  20.64111 1.000 51.36691  ? 77  ASP A CB  1 
ATOM   604  C CG  . ASP A 1 82  ? 27.57673  -10.41690 21.97484 1.000 52.64013  ? 77  ASP A CG  1 
ATOM   605  O OD1 . ASP A 1 82  ? 26.62926  -11.12100 22.38203 1.000 50.84127  ? 77  ASP A OD1 1 
ATOM   606  O OD2 . ASP A 1 82  ? 28.64070  -10.26183 22.60664 1.000 53.74984  ? 77  ASP A OD2 1 
ATOM   607  N N   . ALA A 1 83  ? 26.93431  -9.67755  17.41388 1.000 45.44776  ? 78  ALA A N   1 
ATOM   608  C CA  . ALA A 1 83  ? 26.63824  -8.85965  16.24653 1.000 45.73173  ? 78  ALA A CA  1 
ATOM   609  C C   . ALA A 1 83  ? 25.79188  -9.58490  15.21142 1.000 44.76552  ? 78  ALA A C   1 
ATOM   610  O O   . ALA A 1 83  ? 25.41460  -8.97493  14.20513 1.000 46.15557  ? 78  ALA A O   1 
ATOM   611  C CB  . ALA A 1 83  ? 27.93668  -8.36785  15.59960 1.000 45.51846  ? 78  ALA A CB  1 
ATOM   612  N N   . ALA A 1 84  ? 25.48630  -10.86035 15.43080 1.000 43.86340  ? 79  ALA A N   1 
ATOM   613  C CA  . ALA A 1 84  ? 24.64980  -11.59849 14.49741 1.000 44.17259  ? 79  ALA A CA  1 
ATOM   614  C C   . ALA A 1 84  ? 23.27223  -10.95566 14.39110 1.000 43.86663  ? 79  ALA A C   1 
ATOM   615  O O   . ALA A 1 84  ? 22.77042  -10.34985 15.34089 1.000 41.64593  ? 79  ALA A O   1 
ATOM   616  C CB  . ALA A 1 84  ? 24.51505  -13.05421 14.94358 1.000 47.33672  ? 79  ALA A CB  1 
ATOM   617  N N   . MET A 1 85  ? 22.66438  -11.07689 13.20608 1.000 41.47924  ? 80  MET A N   1 
ATOM   618  C CA  . MET A 1 85  ? 21.29584  -10.59701 13.03191 1.000 42.79439  ? 80  MET A CA  1 
ATOM   619  C C   . MET A 1 85  ? 20.29913  -11.44641 13.81592 1.000 40.91750  ? 80  MET A C   1 
ATOM   620  O O   . MET A 1 85  ? 19.33100  -10.91677 14.37854 1.000 40.40437  ? 80  MET A O   1 
ATOM   621  C CB  . MET A 1 85  ? 20.92548  -10.58652 11.55214 1.000 43.72857  ? 80  MET A CB  1 
ATOM   622  C CG  . MET A 1 85  ? 19.45362  -10.32124 11.29247 1.000 46.62313  ? 80  MET A CG  1 
ATOM   623  S SD  . MET A 1 85  ? 18.99875  -8.59766  11.56436 1.000 48.11448  ? 80  MET A SD  1 
ATOM   624  C CE  . MET A 1 85  ? 19.75260  -7.81816  10.13062 1.000 46.85049  ? 80  MET A CE  1 
ATOM   625  N N   . ILE A 1 86  ? 20.51446  -12.76210 13.85528 1.000 40.10315  ? 81  ILE A N   1 
ATOM   626  C CA  . ILE A 1 86  ? 19.59998  -13.71437 14.47764 1.000 42.23313  ? 81  ILE A CA  1 
ATOM   627  C C   . ILE A 1 86  ? 20.37794  -14.53904 15.49898 1.000 41.84216  ? 81  ILE A C   1 
ATOM   628  O O   . ILE A 1 86  ? 21.44820  -15.07344 15.18660 1.000 42.90386  ? 81  ILE A O   1 
ATOM   629  C CB  . ILE A 1 86  ? 18.94127  -14.62582 13.42528 1.000 44.08190  ? 81  ILE A CB  1 
ATOM   630  C CG1 . ILE A 1 86  ? 18.33547  -13.78795 12.29622 1.000 47.61983  ? 81  ILE A CG1 1 
ATOM   631  C CG2 . ILE A 1 86  ? 17.86955  -15.47805 14.05833 1.000 45.81135  ? 81  ILE A CG2 1 
ATOM   632  C CD1 . ILE A 1 86  ? 17.67693  -14.60815 11.20870 1.000 48.99320  ? 81  ILE A CD1 1 
ATOM   633  N N   . SER A 1 87  ? 19.83613  -14.65616 16.71174 1.000 42.11674  ? 82  SER A N   1 
ATOM   634  C CA  . SER A 1 87  ? 20.54704  -15.37866 17.76028 1.000 43.57635  ? 82  SER A CA  1 
ATOM   635  C C   . SER A 1 87  ? 20.32349  -16.88598 17.66587 1.000 46.21045  ? 82  SER A C   1 
ATOM   636  O O   . SER A 1 87  ? 19.97439  -17.53066 18.65949 1.000 48.06939  ? 82  SER A O   1 
ATOM   637  C CB  . SER A 1 87  ? 20.13701  -14.86092 19.14573 1.000 46.04442  ? 82  SER A CB  1 
ATOM   638  O OG  . SER A 1 87  ? 18.76691  -15.09880 19.41099 1.000 45.97597  ? 82  SER A OG  1 
ATOM   639  N N   . SER A 1 88  ? 20.52477  -17.46157 16.48295 1.000 49.63586  ? 83  SER A N   1 
ATOM   640  C CA  . SER A 1 88  ? 20.45253  -18.90805 16.34186 1.000 52.66479  ? 83  SER A CA  1 
ATOM   641  C C   . SER A 1 88  ? 21.72086  -19.56226 16.89332 1.000 54.90285  ? 83  SER A C   1 
ATOM   642  O O   . SER A 1 88  ? 22.75386  -18.91468 17.08994 1.000 54.08735  ? 83  SER A O   1 
ATOM   643  C CB  . SER A 1 88  ? 20.23632  -19.30080 14.87828 1.000 53.21176  ? 83  SER A CB  1 
ATOM   644  O OG  . SER A 1 88  ? 21.17380  -18.67394 14.01722 1.000 49.72542  ? 83  SER A OG  1 
ATOM   645  N N   . GLY A 1 89  ? 21.62766  -20.86235 17.15469 1.000 55.93112  ? 84  GLY A N   1 
ATOM   646  C CA  . GLY A 1 89  ? 22.71242  -21.61462 17.75170 1.000 55.46830  ? 84  GLY A CA  1 
ATOM   647  C C   . GLY A 1 89  ? 23.60022  -22.28929 16.72513 1.000 55.84932  ? 84  GLY A C   1 
ATOM   648  O O   . GLY A 1 89  ? 23.64338  -21.91075 15.55207 1.000 51.61202  ? 84  GLY A O   1 
ATOM   649  N N   . SER A 1 90  ? 24.32829  -23.30955 17.19098 1.000 58.00678  ? 85  SER A N   1 
ATOM   650  C CA  . SER A 1 90  ? 25.19896  -24.12858 16.34019 1.000 57.84972  ? 85  SER A CA  1 
ATOM   651  C C   . SER A 1 90  ? 26.25848  -23.28820 15.63144 1.000 55.27668  ? 85  SER A C   1 
ATOM   652  O O   . SER A 1 90  ? 26.63240  -23.56629 14.49244 1.000 58.77878  ? 85  SER A O   1 
ATOM   653  C CB  . SER A 1 90  ? 24.38471  -24.93260 15.32487 1.000 57.74474  ? 85  SER A CB  1 
ATOM   654  O OG  . SER A 1 90  ? 24.16317  -26.25142 15.78615 1.000 61.20379  ? 85  SER A OG  1 
ATOM   655  N N   . MET A 1 91  ? 26.76044  -22.26198 16.32010 1.000 55.26550  ? 86  MET A N   1 
ATOM   656  C CA  . MET A 1 91  ? 27.72639  -21.34922 15.71190 1.000 57.58222  ? 86  MET A CA  1 
ATOM   657  C C   . MET A 1 91  ? 29.05532  -22.04248 15.42425 1.000 60.11169  ? 86  MET A C   1 
ATOM   658  O O   . MET A 1 91  ? 29.70463  -21.74959 14.41379 1.000 61.93147  ? 86  MET A O   1 
ATOM   659  C CB  . MET A 1 91  ? 27.93618  -20.13368 16.61910 1.000 60.47476  ? 86  MET A CB  1 
ATOM   660  C CG  . MET A 1 91  ? 28.92325  -19.10110 16.09488 1.000 60.55866  ? 86  MET A CG  1 
ATOM   661  S SD  . MET A 1 91  ? 28.23126  -18.03264 14.81887 1.000 59.11624  ? 86  MET A SD  1 
ATOM   662  C CE  . MET A 1 91  ? 27.10625  -17.01101 15.76108 1.000 62.07654  ? 86  MET A CE  1 
ATOM   663  N N   . THR A 1 92  ? 29.48194  -22.95631 16.29912 1.000 61.59759  ? 87  THR A N   1 
ATOM   664  C CA  . THR A 1 92  ? 30.73452  -23.67059 16.06535 1.000 65.67724  ? 87  THR A CA  1 
ATOM   665  C C   . THR A 1 92  ? 30.65592  -24.51604 14.80150 1.000 66.18912  ? 87  THR A C   1 
ATOM   666  O O   . THR A 1 92  ? 31.60551  -24.55750 14.01090 1.000 67.47102  ? 87  THR A O   1 
ATOM   667  C CB  . THR A 1 92  ? 31.07969  -24.54527 17.27371 1.000 70.53950  ? 87  THR A CB  1 
ATOM   668  O OG1 . THR A 1 92  ? 31.56230  -23.71980 18.34246 1.000 70.60525  ? 87  THR A OG1 1 
ATOM   669  C CG2 . THR A 1 92  ? 32.13929  -25.58876 16.91220 1.000 73.87544  ? 87  THR A CG2 1 
ATOM   670  N N   . ASN A 1 93  ? 29.52623  -25.19095 14.58770 1.000 64.89961  ? 88  ASN A N   1 
ATOM   671  C CA  . ASN A 1 93  ? 29.38152  -26.03521 13.41004 1.000 65.00365  ? 88  ASN A CA  1 
ATOM   672  C C   . ASN A 1 93  ? 29.20830  -25.22271 12.13609 1.000 61.91987  ? 88  ASN A C   1 
ATOM   673  O O   . ASN A 1 93  ? 29.52427  -25.72273 11.05291 1.000 64.71761  ? 88  ASN A O   1 
ATOM   674  C CB  . ASN A 1 93  ? 28.20224  -26.98779 13.59487 1.000 68.17524  ? 88  ASN A CB  1 
ATOM   675  C CG  . ASN A 1 93  ? 28.28933  -27.76878 14.89267 1.000 74.75979  ? 88  ASN A CG  1 
ATOM   676  O OD1 . ASN A 1 93  ? 27.78406  -27.33058 15.93287 1.000 76.03640  ? 88  ASN A OD1 1 
ATOM   677  N ND2 . ASN A 1 93  ? 28.94179  -28.92638 14.84345 1.000 77.41150  ? 88  ASN A ND2 1 
ATOM   678  N N   . ARG A 1 94  ? 28.71610  -23.98594 12.23768 1.000 56.53535  ? 89  ARG A N   1 
ATOM   679  C CA  . ARG A 1 94  ? 28.62934  -23.13464 11.05755 1.000 51.68778  ? 89  ARG A CA  1 
ATOM   680  C C   . ARG A 1 94  ? 29.99826  -22.59913 10.66375 1.000 54.62994  ? 89  ARG A C   1 
ATOM   681  O O   . ARG A 1 94  ? 30.31653  -22.51663 9.47079  1.000 56.76544  ? 89  ARG A O   1 
ATOM   682  C CB  . ARG A 1 94  ? 27.65318  -21.98520 11.29753 1.000 48.40449  ? 89  ARG A CB  1 
ATOM   683  C CG  . ARG A 1 94  ? 26.19723  -22.34833 11.04905 1.000 49.15099  ? 89  ARG A CG  1 
ATOM   684  C CD  . ARG A 1 94  ? 25.29585  -21.14563 11.25473 1.000 48.49184  ? 89  ARG A CD  1 
ATOM   685  N NE  . ARG A 1 94  ? 25.09986  -20.85084 12.66863 1.000 52.72884  ? 89  ARG A NE  1 
ATOM   686  C CZ  . ARG A 1 94  ? 24.73552  -19.66214 13.13511 1.000 52.88781  ? 89  ARG A CZ  1 
ATOM   687  N NH1 . ARG A 1 94  ? 24.53640  -18.64984 12.29592 1.000 48.09886  ? 89  ARG A NH1 1 
ATOM   688  N NH2 . ARG A 1 94  ? 24.58017  -19.48433 14.43927 1.000 53.66389  ? 89  ARG A NH2 1 
ATOM   689  N N   . ILE A 1 95  ? 30.82163  -22.22668 11.64662 1.000 54.09161  ? 90  ILE A N   1 
ATOM   690  C CA  . ILE A 1 95  ? 32.17371  -21.77139 11.33462 1.000 55.34323  ? 90  ILE A CA  1 
ATOM   691  C C   . ILE A 1 95  ? 32.98914  -22.91088 10.73399 1.000 60.51029  ? 90  ILE A C   1 
ATOM   692  O O   . ILE A 1 95  ? 33.74846  -22.71454 9.77451  1.000 60.75135  ? 90  ILE A O   1 
ATOM   693  C CB  . ILE A 1 95  ? 32.84060  -21.17920 12.58898 1.000 50.32979  ? 90  ILE A CB  1 
ATOM   694  C CG1 . ILE A 1 95  ? 32.19260  -19.84159 12.95049 1.000 46.59685  ? 90  ILE A CG1 1 
ATOM   695  C CG2 . ILE A 1 95  ? 34.33015  -20.99275 12.37178 1.000 52.91312  ? 90  ILE A CG2 1 
ATOM   696  C CD1 . ILE A 1 95  ? 32.29294  -19.50627 14.44610 1.000 50.60830  ? 90  ILE A CD1 1 
ATOM   697  N N   . ASP A 1 96  ? 32.82828  -24.12415 11.27167 1.000 60.98434  ? 91  ASP A N   1 
ATOM   698  C CA  . ASP A 1 96  ? 33.48165  -25.29103 10.68389 1.000 64.29109  ? 91  ASP A CA  1 
ATOM   699  C C   . ASP A 1 96  ? 33.09536  -25.45362 9.21987  1.000 62.35023  ? 91  ASP A C   1 
ATOM   700  O O   . ASP A 1 96  ? 33.96131  -25.57813 8.34551  1.000 63.05011  ? 91  ASP A O   1 
ATOM   701  C CB  . ASP A 1 96  ? 33.11620  -26.55358 11.46469 1.000 68.28555  ? 91  ASP A CB  1 
ATOM   702  C CG  . ASP A 1 96  ? 33.74951  -26.59900 12.83704 1.000 72.06313  ? 91  ASP A CG  1 
ATOM   703  O OD1 . ASP A 1 96  ? 34.62024  -25.75250 13.11982 1.000 73.21473  ? 91  ASP A OD1 1 
ATOM   704  O OD2 . ASP A 1 96  ? 33.37014  -27.48029 13.63617 1.000 75.78685  ? 91  ASP A OD2 1 
ATOM   705  N N   . ARG A 1 97  ? 31.78954  -25.45333 8.94002  1.000 60.25215  ? 92  ARG A N   1 
ATOM   706  C CA  . ARG A 1 97  ? 31.31019  -25.63399 7.57419  1.000 60.36829  ? 92  ARG A CA  1 
ATOM   707  C C   . ARG A 1 97  ? 31.88056  -24.56573 6.65084  1.000 56.04511  ? 92  ARG A C   1 
ATOM   708  O O   . ARG A 1 97  ? 32.41039  -24.87598 5.57756  1.000 54.37593  ? 92  ARG A O   1 
ATOM   709  C CB  . ARG A 1 97  ? 29.78078  -25.61166 7.55805  1.000 60.34835  ? 92  ARG A CB  1 
ATOM   710  C CG  . ARG A 1 97  ? 29.14461  -26.78223 6.82656  1.000 63.33928  ? 92  ARG A CG  1 
ATOM   711  C CD  . ARG A 1 97  ? 29.38615  -26.69836 5.32450  1.000 64.33793  ? 92  ARG A CD  1 
ATOM   712  N NE  . ARG A 1 97  ? 28.74111  -25.53268 4.72195  1.000 62.05156  ? 92  ARG A NE  1 
ATOM   713  C CZ  . ARG A 1 97  ? 28.90512  -25.15695 3.45616  1.000 60.01133  ? 92  ARG A CZ  1 
ATOM   714  N NH1 . ARG A 1 97  ? 29.69754  -25.85567 2.65545  1.000 63.32503  ? 92  ARG A NH1 1 
ATOM   715  N NH2 . ARG A 1 97  ? 28.28036  -24.08156 2.99033  1.000 55.96407  ? 92  ARG A NH2 1 
ATOM   716  N N   . LEU A 1 98  ? 31.80869  -23.29878 7.07289  1.000 54.43061  ? 93  LEU A N   1 
ATOM   717  C CA  . LEU A 1 98  ? 32.31290  -22.19978 6.25587  1.000 55.49916  ? 93  LEU A CA  1 
ATOM   718  C C   . LEU A 1 98  ? 33.82518  -22.26612 6.07100  1.000 57.60190  ? 93  LEU A C   1 
ATOM   719  O O   . LEU A 1 98  ? 34.34242  -21.79522 5.05222  1.000 56.93763  ? 93  LEU A O   1 
ATOM   720  C CB  . LEU A 1 98  ? 31.91928  -20.86215 6.87894  1.000 53.75167  ? 93  LEU A CB  1 
ATOM   721  C CG  . LEU A 1 98  ? 30.42259  -20.56428 6.93689  1.000 52.65059  ? 93  LEU A CG  1 
ATOM   722  C CD1 . LEU A 1 98  ? 30.17410  -19.24554 7.64189  1.000 51.88458  ? 93  LEU A CD1 1 
ATOM   723  C CD2 . LEU A 1 98  ? 29.82303  -20.55055 5.54487  1.000 51.04782  ? 93  LEU A CD2 1 
ATOM   724  N N   . GLU A 1 99  ? 34.55002  -22.83065 7.03788  1.000 60.79751  ? 94  GLU A N   1 
ATOM   725  C CA  . GLU A 1 99  ? 35.99591  -22.95752 6.88625  1.000 64.15803  ? 94  GLU A CA  1 
ATOM   726  C C   . GLU A 1 99  ? 36.34736  -24.03548 5.86971  1.000 64.93676  ? 94  GLU A C   1 
ATOM   727  O O   . GLU A 1 99  ? 37.28463  -23.86960 5.08102  1.000 66.04476  ? 94  GLU A O   1 
ATOM   728  C CB  . GLU A 1 99  ? 36.64493  -23.26019 8.23549  1.000 69.60093  ? 94  GLU A CB  1 
ATOM   729  C CG  . GLU A 1 99  ? 38.15561  -23.10538 8.23421  1.000 75.99874  ? 94  GLU A CG  1 
ATOM   730  C CD  . GLU A 1 99  ? 38.78025  -23.47084 9.56712  1.000 80.10776  ? 94  GLU A CD  1 
ATOM   731  O OE1 . GLU A 1 99  ? 38.09888  -24.12384 10.38778 1.000 80.02207  ? 94  GLU A OE1 1 
ATOM   732  O OE2 . GLU A 1 99  ? 39.95212  -23.10180 9.79253  1.000 83.31965  ? 94  GLU A OE2 1 
ATOM   733  N N   . LYS A 1 100 ? 35.60446  -25.14644 5.87011  1.000 63.59064  ? 95  LYS A N   1 
ATOM   734  C CA  . LYS A 1 100 ? 35.83976  -26.18854 4.87701  1.000 64.69031  ? 95  LYS A CA  1 
ATOM   735  C C   . LYS A 1 100 ? 35.52748  -25.69636 3.47069  1.000 62.36579  ? 95  LYS A C   1 
ATOM   736  O O   . LYS A 1 100 ? 36.15717  -26.14069 2.50640  1.000 66.64136  ? 95  LYS A O   1 
ATOM   737  C CB  . LYS A 1 100 ? 35.00699  -27.43023 5.19961  1.000 64.70445  ? 95  LYS A CB  1 
ATOM   738  C CG  . LYS A 1 100 ? 35.36276  -28.65401 4.36124  1.000 68.05835  ? 95  LYS A CG  1 
ATOM   739  C CD  . LYS A 1 100 ? 34.44359  -29.83239 4.65925  1.000 68.94065  ? 95  LYS A CD  1 
ATOM   740  N N   . ALA A 1 101 ? 34.56640  -24.78064 3.33419  1.000 57.98385  ? 96  ALA A N   1 
ATOM   741  C CA  . ALA A 1 101 ? 34.21797  -24.21401 2.03796  1.000 56.18478  ? 96  ALA A CA  1 
ATOM   742  C C   . ALA A 1 101 ? 35.19580  -23.14400 1.57516  1.000 55.29531  ? 96  ALA A C   1 
ATOM   743  O O   . ALA A 1 101 ? 35.12659  -22.72676 0.41330  1.000 54.50835  ? 96  ALA A O   1 
ATOM   744  C CB  . ALA A 1 101 ? 32.80531  -23.62746 2.08052  1.000 52.60810  ? 96  ALA A CB  1 
ATOM   745  N N   . GLY A 1 102 ? 36.09477  -22.69320 2.44558  1.000 57.48781  ? 97  GLY A N   1 
ATOM   746  C CA  . GLY A 1 102 ? 37.07032  -21.68659 2.07966  1.000 55.96078  ? 97  GLY A CA  1 
ATOM   747  C C   . GLY A 1 102 ? 36.60322  -20.25822 2.21783  1.000 51.00034  ? 97  GLY A C   1 
ATOM   748  O O   . GLY A 1 102 ? 37.21777  -19.36286 1.62892  1.000 50.67309  ? 97  GLY A O   1 
ATOM   749  N N   . TRP A 1 103 ? 35.54223  -20.00978 2.98418  1.000 48.42912  ? 98  TRP A N   1 
ATOM   750  C CA  . TRP A 1 103 ? 34.98947  -18.67011 3.10961  1.000 47.29515  ? 98  TRP A CA  1 
ATOM   751  C C   . TRP A 1 103 ? 35.37221  -17.96548 4.40450  1.000 48.41640  ? 98  TRP A C   1 
ATOM   752  O O   . TRP A 1 103 ? 35.31120  -16.73267 4.45429  1.000 49.37726  ? 98  TRP A O   1 
ATOM   753  C CB  . TRP A 1 103 ? 33.46385  -18.72607 2.97760  1.000 47.35740  ? 98  TRP A CB  1 
ATOM   754  C CG  . TRP A 1 103 ? 33.03880  -19.21888 1.62206  1.000 52.18576  ? 98  TRP A CG  1 
ATOM   755  C CD1 . TRP A 1 103 ? 33.67185  -18.99037 0.42661  1.000 49.81835  ? 98  TRP A CD1 1 
ATOM   756  C CD2 . TRP A 1 103 ? 31.90681  -20.04303 1.32315  1.000 54.09960  ? 98  TRP A CD2 1 
ATOM   757  N NE1 . TRP A 1 103 ? 32.99472  -19.61057 -0.59068 1.000 50.79236  ? 98  TRP A NE1 1 
ATOM   758  C CE2 . TRP A 1 103 ? 31.90964  -20.26571 -0.06953 1.000 52.21116  ? 98  TRP A CE2 1 
ATOM   759  C CE3 . TRP A 1 103 ? 30.88775  -20.60984 2.09746  1.000 55.05247  ? 98  TRP A CE3 1 
ATOM   760  C CZ2 . TRP A 1 103 ? 30.93503  -21.02870 -0.70401 1.000 55.54480  ? 98  TRP A CZ2 1 
ATOM   761  C CZ3 . TRP A 1 103 ? 29.92085  -21.36728 1.46693  1.000 56.72027  ? 98  TRP A CZ3 1 
ATOM   762  C CH2 . TRP A 1 103 ? 29.95131  -21.57073 0.07739  1.000 56.22979  ? 98  TRP A CH2 1 
ATOM   763  N N   . VAL A 1 104 ? 35.75840  -18.70221 5.44891  1.000 51.75915  ? 99  VAL A N   1 
ATOM   764  C CA  . VAL A 1 104 ? 36.28751  -18.10502 6.66704  1.000 51.01717  ? 99  VAL A CA  1 
ATOM   765  C C   . VAL A 1 104 ? 37.57588  -18.82382 7.03811  1.000 56.25151  ? 99  VAL A C   1 
ATOM   766  O O   . VAL A 1 104 ? 37.83538  -19.95090 6.61146  1.000 53.21435  ? 99  VAL A O   1 
ATOM   767  C CB  . VAL A 1 104 ? 35.29242  -18.15091 7.85599  1.000 48.76490  ? 99  VAL A CB  1 
ATOM   768  C CG1 . VAL A 1 104 ? 33.96683  -17.50328 7.48266  1.000 44.33302  ? 99  VAL A CG1 1 
ATOM   769  C CG2 . VAL A 1 104 ? 35.08731  -19.57876 8.33822  1.000 45.94818  ? 99  VAL A CG2 1 
ATOM   770  N N   . GLU A 1 105 ? 38.38905  -18.14643 7.84449  1.000 59.38573  ? 100 GLU A N   1 
ATOM   771  C CA  . GLU A 1 105 ? 39.56555  -18.74702 8.45451  1.000 66.08061  ? 100 GLU A CA  1 
ATOM   772  C C   . GLU A 1 105 ? 39.64990  -18.27970 9.90052  1.000 65.14192  ? 100 GLU A C   1 
ATOM   773  O O   . GLU A 1 105 ? 38.94892  -17.35401 10.31962 1.000 59.04120  ? 100 GLU A O   1 
ATOM   774  C CB  . GLU A 1 105 ? 40.84643  -18.39201 7.69334  1.000 71.25062  ? 100 GLU A CB  1 
ATOM   775  C CG  . GLU A 1 105 ? 41.26643  -16.94069 7.83892  1.000 73.69712  ? 100 GLU A CG  1 
ATOM   776  C CD  . GLU A 1 105 ? 42.34997  -16.55164 6.85638  1.000 77.43988  ? 100 GLU A CD  1 
ATOM   777  O OE1 . GLU A 1 105 ? 42.72084  -17.40039 6.01609  1.000 76.50168  ? 100 GLU A OE1 1 
ATOM   778  O OE2 . GLU A 1 105 ? 42.82520  -15.39830 6.92608  1.000 80.49356  ? 100 GLU A OE2 1 
ATOM   779  N N   . ARG A 1 106 ? 40.52436  -18.92489 10.66512 1.000 72.17144  ? 101 ARG A N   1 
ATOM   780  C CA  . ARG A 1 106 ? 40.65206  -18.67504 12.10004 1.000 78.01978  ? 101 ARG A CA  1 
ATOM   781  C C   . ARG A 1 106 ? 42.05202  -18.14647 12.39886 1.000 85.35695  ? 101 ARG A C   1 
ATOM   782  O O   . ARG A 1 106 ? 43.01467  -18.91663 12.45768 1.000 90.39755  ? 101 ARG A O   1 
ATOM   783  C CB  . ARG A 1 106 ? 40.35358  -19.94253 12.89256 1.000 79.23005  ? 101 ARG A CB  1 
ATOM   784  C CG  . ARG A 1 106 ? 38.87602  -20.31290 12.93217 1.000 76.09696  ? 101 ARG A CG  1 
ATOM   785  C CD  . ARG A 1 106 ? 38.70115  -21.80361 13.18082 1.000 78.81550  ? 101 ARG A CD  1 
ATOM   786  N NE  . ARG A 1 106 ? 37.38587  -22.13205 13.72151 1.000 75.86492  ? 101 ARG A NE  1 
ATOM   787  C CZ  . ARG A 1 106 ? 36.79483  -23.31142 13.56754 1.000 76.75519  ? 101 ARG A CZ  1 
ATOM   788  N NH1 . ARG A 1 106 ? 35.59964  -23.53300 14.09503 1.000 74.64281  ? 101 ARG A NH1 1 
ATOM   789  N NH2 . ARG A 1 106 ? 37.39546  -24.26704 12.87275 1.000 81.37074  ? 101 ARG A NH2 1 
ATOM   790  N N   . ARG A 1 107 ? 42.16054  -16.83306 12.58023 1.000 88.35431  ? 102 ARG A N   1 
ATOM   791  C CA  . ARG A 1 107 ? 43.38264  -16.18378 13.02120 1.000 92.73162  ? 102 ARG A CA  1 
ATOM   792  C C   . ARG A 1 107 ? 43.32947  -16.00225 14.54051 1.000 96.84270  ? 102 ARG A C   1 
ATOM   793  O O   . ARG A 1 107 ? 42.45789  -16.55158 15.22428 1.000 99.90831  ? 102 ARG A O   1 
ATOM   794  C CB  . ARG A 1 107 ? 43.56767  -14.85643 12.27914 1.000 90.42205  ? 102 ARG A CB  1 
ATOM   795  N N   . ALA A 1 108 ? 44.26598  -15.22973 15.08408 1.000 103.31431 ? 103 ALA A N   1 
ATOM   796  C CA  . ALA A 1 108 ? 44.31458  -15.01433 16.52831 1.000 104.54670 ? 103 ALA A CA  1 
ATOM   797  C C   . ALA A 1 108 ? 44.78194  -13.60147 16.87089 1.000 104.18263 ? 103 ALA A C   1 
ATOM   798  O O   . ALA A 1 108 ? 44.36921  -13.02721 17.88134 1.000 103.29938 ? 103 ALA A O   1 
ATOM   799  C CB  . ALA A 1 108 ? 45.21863  -16.04948 17.18390 1.000 109.52904 ? 103 ALA A CB  1 
ATOM   800  N N   . THR A 1 116 ? 41.75898  -15.48526 19.53956 1.000 100.50252 ? 111 THR A N   1 
ATOM   801  C CA  . THR A 1 116 ? 40.97672  -16.22437 18.55107 1.000 97.87423  ? 111 THR A CA  1 
ATOM   802  C C   . THR A 1 116 ? 40.03141  -15.31248 17.78081 1.000 90.89560  ? 111 THR A C   1 
ATOM   803  O O   . THR A 1 116 ? 39.19656  -14.62093 18.36910 1.000 90.06372  ? 111 THR A O   1 
ATOM   804  C CB  . THR A 1 116 ? 40.14997  -17.35070 19.19948 1.000 101.43222 ? 111 THR A CB  1 
ATOM   805  O OG1 . THR A 1 116 ? 41.00183  -18.46541 19.48949 1.000 108.36342 ? 111 THR A OG1 1 
ATOM   806  C CG2 . THR A 1 116 ? 39.02268  -17.80058 18.26993 1.000 95.36468  ? 111 THR A CG2 1 
ATOM   807  N N   . LEU A 1 117 ? 40.16783  -15.32135 16.45748 1.000 84.70957  ? 112 LEU A N   1 
ATOM   808  C CA  . LEU A 1 117 ? 39.33055  -14.52473 15.57694 1.000 80.18258  ? 112 LEU A CA  1 
ATOM   809  C C   . LEU A 1 117 ? 38.83641  -15.39259 14.42998 1.000 74.15432  ? 112 LEU A C   1 
ATOM   810  O O   . LEU A 1 117 ? 39.51577  -16.32967 14.00486 1.000 74.49990  ? 112 LEU A O   1 
ATOM   811  C CB  . LEU A 1 117 ? 40.09231  -13.31123 15.01411 1.000 83.04191  ? 112 LEU A CB  1 
ATOM   812  C CG  . LEU A 1 117 ? 40.74660  -12.34733 16.00804 1.000 87.95542  ? 112 LEU A CG  1 
ATOM   813  C CD1 . LEU A 1 117 ? 41.64861  -11.35929 15.27820 1.000 89.41403  ? 112 LEU A CD1 1 
ATOM   814  C CD2 . LEU A 1 117 ? 39.69637  -11.61012 16.82571 1.000 87.86615  ? 112 LEU A CD2 1 
ATOM   815  N N   . VAL A 1 118 ? 37.63742  -15.08298 13.94401 1.000 68.23983  ? 113 VAL A N   1 
ATOM   816  C CA  . VAL A 1 118 ? 37.10233  -15.66017 12.71566 1.000 62.72952  ? 113 VAL A CA  1 
ATOM   817  C C   . VAL A 1 118 ? 37.12845  -14.57217 11.65562 1.000 59.61715  ? 113 VAL A C   1 
ATOM   818  O O   . VAL A 1 118 ? 36.62958  -13.46591 11.88921 1.000 60.33737  ? 113 VAL A O   1 
ATOM   819  C CB  . VAL A 1 118 ? 35.67837  -16.20739 12.91351 1.000 59.65563  ? 113 VAL A CB  1 
ATOM   820  C CG1 . VAL A 1 118 ? 35.14734  -16.78960 11.61200 1.000 55.52827  ? 113 VAL A CG1 1 
ATOM   821  C CG2 . VAL A 1 118 ? 35.66442  -17.25079 14.02620 1.000 61.43739  ? 113 VAL A CG2 1 
ATOM   822  N N   . ALA A 1 119 ? 37.71373  -14.87762 10.49752 1.000 58.90492  ? 114 ALA A N   1 
ATOM   823  C CA  . ALA A 1 119 ? 37.95391  -13.87296 9.46867  1.000 57.23855  ? 114 ALA A CA  1 
ATOM   824  C C   . ALA A 1 119 ? 37.46607  -14.35467 8.10993  1.000 55.90297  ? 114 ALA A C   1 
ATOM   825  O O   . ALA A 1 119 ? 37.72893  -15.49601 7.71573  1.000 57.66774  ? 114 ALA A O   1 
ATOM   826  C CB  . ALA A 1 119 ? 39.44154  -13.51348 9.38371  1.000 59.64375  ? 114 ALA A CB  1 
ATOM   827  N N   . LEU A 1 120 ? 36.76361  -13.47418 7.39928  1.000 52.65660  ? 115 LEU A N   1 
ATOM   828  C CA  . LEU A 1 120 ? 36.44428  -13.71364 6.00026  1.000 52.04784  ? 115 LEU A CA  1 
ATOM   829  C C   . LEU A 1 120 ? 37.71807  -13.94313 5.20399  1.000 51.72180  ? 115 LEU A C   1 
ATOM   830  O O   . LEU A 1 120 ? 38.69823  -13.20845 5.35456  1.000 52.77954  ? 115 LEU A O   1 
ATOM   831  C CB  . LEU A 1 120 ? 35.69397  -12.51933 5.41230  1.000 53.04655  ? 115 LEU A CB  1 
ATOM   832  C CG  . LEU A 1 120 ? 34.21830  -12.30241 5.71923  1.000 50.73481  ? 115 LEU A CG  1 
ATOM   833  C CD1 . LEU A 1 120 ? 33.74078  -11.06633 4.98339  1.000 51.61820  ? 115 LEU A CD1 1 
ATOM   834  C CD2 . LEU A 1 120 ? 33.40604  -13.51372 5.31271  1.000 48.45682  ? 115 LEU A CD2 1 
ATOM   835  N N   . THR A 1 121 ? 37.70709  -14.96824 4.36262  1.000 51.61612  ? 116 THR A N   1 
ATOM   836  C CA  . THR A 1 121 ? 38.72291  -15.07358 3.33057  1.000 54.87746  ? 116 THR A CA  1 
ATOM   837  C C   . THR A 1 121 ? 38.39275  -14.10421 2.19781  1.000 51.14388  ? 116 THR A C   1 
ATOM   838  O O   . THR A 1 121 ? 37.34109  -13.45916 2.18745  1.000 48.56441  ? 116 THR A O   1 
ATOM   839  C CB  . THR A 1 121 ? 38.81091  -16.50440 2.80774  1.000 57.96420  ? 116 THR A CB  1 
ATOM   840  O OG1 . THR A 1 121 ? 37.58821  -16.83340 2.13976  1.000 58.27771  ? 116 THR A OG1 1 
ATOM   841  C CG2 . THR A 1 121 ? 39.02711  -17.47875 3.96609  1.000 59.86615  ? 116 THR A CG2 1 
ATOM   842  N N   . SER A 1 122 ? 39.30930  -13.99041 1.23309  1.000 52.84477  ? 117 SER A N   1 
ATOM   843  C CA  . SER A 1 122 ? 39.01683  -13.16795 0.06393  1.000 54.50702  ? 117 SER A CA  1 
ATOM   844  C C   . SER A 1 122 ? 37.83200  -13.73241 -0.70898 1.000 53.41388  ? 117 SER A C   1 
ATOM   845  O O   . SER A 1 122 ? 36.93806  -12.98579 -1.12613 1.000 54.64099  ? 117 SER A O   1 
ATOM   846  C CB  . SER A 1 122 ? 40.25096  -13.05759 -0.83524 1.000 59.82762  ? 117 SER A CB  1 
ATOM   847  O OG  . SER A 1 122 ? 40.58712  -14.31042 -1.40066 1.000 61.69421  ? 117 SER A OG  1 
ATOM   848  N N   . ALA A 1 123 ? 37.80171  -15.05470 -0.89690 1.000 53.87369  ? 118 ALA A N   1 
ATOM   849  C CA  . ALA A 1 123 ? 36.65893  -15.68355 -1.55139 1.000 49.87719  ? 118 ALA A CA  1 
ATOM   850  C C   . ALA A 1 123 ? 35.38857  -15.48749 -0.73793 1.000 48.92023  ? 118 ALA A C   1 
ATOM   851  O O   . ALA A 1 123 ? 34.30446  -15.28552 -1.29888 1.000 46.10728  ? 118 ALA A O   1 
ATOM   852  C CB  . ALA A 1 123 ? 36.93238  -17.17162 -1.77501 1.000 48.09798  ? 118 ALA A CB  1 
ATOM   853  N N   . GLY A 1 124 ? 35.50263  -15.53554 0.58961  1.000 48.03110  ? 119 GLY A N   1 
ATOM   854  C CA  . GLY A 1 124 ? 34.34210  -15.28941 1.42493  1.000 46.26806  ? 119 GLY A CA  1 
ATOM   855  C C   . GLY A 1 124 ? 33.85749  -13.85647 1.33872  1.000 43.49994  ? 119 GLY A C   1 
ATOM   856  O O   . GLY A 1 124 ? 32.65175  -13.60334 1.28632  1.000 42.52109  ? 119 GLY A O   1 
ATOM   857  N N   . ARG A 1 125 ? 34.78527  -12.89904 1.33627  1.000 45.32386  ? 120 ARG A N   1 
ATOM   858  C CA  . ARG A 1 125 ? 34.39424  -11.49964 1.21640  1.000 46.06298  ? 120 ARG A CA  1 
ATOM   859  C C   . ARG A 1 125 ? 33.67066  -11.24981 -0.10522 1.000 52.24520  ? 120 ARG A C   1 
ATOM   860  O O   . ARG A 1 125 ? 32.60294  -10.62686 -0.13684 1.000 45.62399  ? 120 ARG A O   1 
ATOM   861  C CB  . ARG A 1 125 ? 35.62866  -10.60744 1.34650  1.000 48.54273  ? 120 ARG A CB  1 
ATOM   862  C CG  . ARG A 1 125 ? 35.34255  -9.11338  1.36201  1.000 55.10047  ? 120 ARG A CG  1 
ATOM   863  C CD  . ARG A 1 125 ? 35.91717  -8.44515  0.13123  1.000 57.56956  ? 120 ARG A CD  1 
ATOM   864  N NE  . ARG A 1 125 ? 35.75209  -6.99378  0.14315  1.000 60.56273  ? 120 ARG A NE  1 
ATOM   865  C CZ  . ARG A 1 125 ? 36.75596  -6.12684  0.24492  1.000 63.40241  ? 120 ARG A CZ  1 
ATOM   866  N NH1 . ARG A 1 125 ? 38.00556  -6.56203  0.34744  1.000 65.00440  ? 120 ARG A NH1 1 
ATOM   867  N NH2 . ARG A 1 125 ? 36.51209  -4.82282  0.23817  1.000 64.69138  ? 120 ARG A NH2 1 
ATOM   868  N N   . ALA A 1 126 ? 34.23164  -11.74990 -1.20849 1.000 52.30365  ? 121 ALA A N   1 
ATOM   869  C CA  . ALA A 1 126 ? 33.59153  -11.56773 -2.50743 1.000 51.62898  ? 121 ALA A CA  1 
ATOM   870  C C   . ALA A 1 126 ? 32.21941  -12.22756 -2.54711 1.000 49.90836  ? 121 ALA A C   1 
ATOM   871  O O   . ALA A 1 126 ? 31.26739  -11.66188 -3.10005 1.000 49.58662  ? 121 ALA A O   1 
ATOM   872  C CB  . ALA A 1 126 ? 34.48291  -12.12322 -3.61482 1.000 53.23206  ? 121 ALA A CB  1 
ATOM   873  N N   . LEU A 1 127 ? 32.09553  -13.42312 -1.96268 1.000 49.62173  ? 122 LEU A N   1 
ATOM   874  C CA  . LEU A 1 127 ? 30.81056  -14.11617 -1.95954 1.000 48.06533  ? 122 LEU A CA  1 
ATOM   875  C C   . LEU A 1 127 ? 29.74218  -13.28368 -1.26359 1.000 46.50395  ? 122 LEU A C   1 
ATOM   876  O O   . LEU A 1 127 ? 28.64947  -13.07782 -1.80448 1.000 45.74319  ? 122 LEU A O   1 
ATOM   877  C CB  . LEU A 1 127 ? 30.94612  -15.48605 -1.29193 1.000 46.32158  ? 122 LEU A CB  1 
ATOM   878  C CG  . LEU A 1 127 ? 29.64289  -16.25166 -1.03934 1.000 46.45480  ? 122 LEU A CG  1 
ATOM   879  C CD1 . LEU A 1 127 ? 28.94181  -16.61157 -2.33500 1.000 51.24022  ? 122 LEU A CD1 1 
ATOM   880  C CD2 . LEU A 1 127 ? 29.90391  -17.49747 -0.22891 1.000 46.53988  ? 122 LEU A CD2 1 
ATOM   881  N N   . ILE A 1 128 ? 30.04714  -12.77567 -0.06689 1.000 45.78956  ? 123 ILE A N   1 
ATOM   882  C CA  . ILE A 1 128 ? 29.02909  -12.04213 0.67658  1.000 44.38187  ? 123 ILE A CA  1 
ATOM   883  C C   . ILE A 1 128 ? 28.76768  -10.68186 0.04049  1.000 45.65119  ? 123 ILE A C   1 
ATOM   884  O O   . ILE A 1 128 ? 27.63391  -10.18517 0.07574  1.000 44.40168  ? 123 ILE A O   1 
ATOM   885  C CB  . ILE A 1 128 ? 29.41638  -11.91980 2.16635  1.000 42.25171  ? 123 ILE A CB  1 
ATOM   886  C CG1 . ILE A 1 128 ? 28.25846  -11.31908 2.95903  1.000 39.36838  ? 123 ILE A CG1 1 
ATOM   887  C CG2 . ILE A 1 128 ? 30.67475  -11.07823 2.35283  1.000 42.02232  ? 123 ILE A CG2 1 
ATOM   888  C CD1 . ILE A 1 128 ? 26.98167  -12.10754 2.83625  1.000 40.11398  ? 123 ILE A CD1 1 
ATOM   889  N N   . ASP A 1 129 ? 29.79166  -10.06057 -0.55738 1.000 44.25932  ? 124 ASP A N   1 
ATOM   890  C CA  . ASP A 1 129 ? 29.57442  -8.80206  -1.26479 1.000 46.56211  ? 124 ASP A CA  1 
ATOM   891  C C   . ASP A 1 129 ? 28.58394  -8.98922  -2.40502 1.000 49.20440  ? 124 ASP A C   1 
ATOM   892  O O   . ASP A 1 129 ? 27.76325  -8.10669  -2.67986 1.000 50.21549  ? 124 ASP A O   1 
ATOM   893  C CB  . ASP A 1 129 ? 30.90104  -8.25302  -1.79863 1.000 50.40074  ? 124 ASP A CB  1 
ATOM   894  C CG  . ASP A 1 129 ? 31.59914  -7.32723  -0.81287 1.000 51.34171  ? 124 ASP A CG  1 
ATOM   895  O OD1 . ASP A 1 129 ? 30.92804  -6.80057  0.09855  1.000 49.66619  ? 124 ASP A OD1 1 
ATOM   896  O OD2 . ASP A 1 129 ? 32.82143  -7.11419  -0.96660 1.000 51.50958  ? 124 ASP A OD2 1 
ATOM   897  N N   . ASP A 1 130 ? 28.64435  -10.14296 -3.07185 1.000 49.39781  ? 125 ASP A N   1 
ATOM   898  C CA  . ASP A 1 130 ? 27.70091  -10.45384 -4.14005 1.000 49.66254  ? 125 ASP A CA  1 
ATOM   899  C C   . ASP A 1 130 ? 26.34130  -10.84800 -3.57335 1.000 48.26387  ? 125 ASP A C   1 
ATOM   900  O O   . ASP A 1 130 ? 25.29766  -10.37733 -4.04348 1.000 47.48522  ? 125 ASP A O   1 
ATOM   901  C CB  . ASP A 1 130 ? 28.27283  -11.57623 -5.00595 1.000 53.43844  ? 125 ASP A CB  1 
ATOM   902  C CG  . ASP A 1 130 ? 27.58967  -11.68844 -6.35488 1.000 62.12100  ? 125 ASP A CG  1 
ATOM   903  O OD1 . ASP A 1 130 ? 26.66713  -10.89188 -6.63896 1.000 65.94537  ? 125 ASP A OD1 1 
ATOM   904  O OD2 . ASP A 1 130 ? 27.98650  -12.58071 -7.13095 1.000 64.55145  ? 125 ASP A OD2 1 
ATOM   905  N N   . ALA A 1 131 ? 26.33792  -11.69836 -2.54208 1.000 43.19401  ? 126 ALA A N   1 
ATOM   906  C CA  . ALA A 1 131 ? 25.08583  -12.25175 -2.03913 1.000 44.56353  ? 126 ALA A CA  1 
ATOM   907  C C   . ALA A 1 131 ? 24.20783  -11.17862 -1.40821 1.000 46.90660  ? 126 ALA A C   1 
ATOM   908  O O   . ALA A 1 131 ? 22.97980  -11.20658 -1.55963 1.000 46.50869  ? 126 ALA A O   1 
ATOM   909  C CB  . ALA A 1 131 ? 25.37014  -13.36323 -1.02551 1.000 41.21806  ? 126 ALA A CB  1 
ATOM   910  N N   . VAL A 1 132 ? 24.81336  -10.23070 -0.68931 1.000 48.71587  ? 127 VAL A N   1 
ATOM   911  C CA  . VAL A 1 132 ? 24.01009  -9.27258  0.06162  1.000 49.42607  ? 127 VAL A CA  1 
ATOM   912  C C   . VAL A 1 132 ? 23.21143  -8.37842  -0.88172 1.000 49.82945  ? 127 VAL A C   1 
ATOM   913  O O   . VAL A 1 132 ? 22.08333  -7.98278  -0.56233 1.000 54.42787  ? 127 VAL A O   1 
ATOM   914  C CB  . VAL A 1 132 ? 24.89868  -8.46093  1.02432  1.000 46.39636  ? 127 VAL A CB  1 
ATOM   915  C CG1 . VAL A 1 132 ? 25.80645  -7.51242  0.26895  1.000 45.26036  ? 127 VAL A CG1 1 
ATOM   916  C CG2 . VAL A 1 132 ? 24.03802  -7.70771  2.03196  1.000 48.11871  ? 127 VAL A CG2 1 
ATOM   917  N N   . VAL A 1 133 ? 23.75593  -8.06494  -2.05902 1.000 49.91891  ? 128 VAL A N   1 
ATOM   918  C CA  . VAL A 1 133 ? 22.99116  -7.30486  -3.04366 1.000 51.49194  ? 128 VAL A CA  1 
ATOM   919  C C   . VAL A 1 133 ? 21.74811  -8.08187  -3.46097 1.000 50.53144  ? 128 VAL A C   1 
ATOM   920  O O   . VAL A 1 133 ? 20.62828  -7.55622  -3.44353 1.000 52.65036  ? 128 VAL A O   1 
ATOM   921  C CB  . VAL A 1 133 ? 23.86937  -6.95009  -4.25714 1.000 53.99979  ? 128 VAL A CB  1 
ATOM   922  C CG1 . VAL A 1 133 ? 23.00992  -6.39887  -5.38176 1.000 55.97920  ? 128 VAL A CG1 1 
ATOM   923  C CG2 . VAL A 1 133 ? 24.92939  -5.93478  -3.86560 1.000 56.78502  ? 128 VAL A CG2 1 
ATOM   924  N N   . ALA A 1 134 ? 21.92318  -9.34891  -3.83975 1.000 47.71780  ? 129 ALA A N   1 
ATOM   925  C CA  . ALA A 1 134 ? 20.76307  -10.13965 -4.23540 1.000 49.80208  ? 129 ALA A CA  1 
ATOM   926  C C   . ALA A 1 134 ? 19.83086  -10.36873 -3.05704 1.000 47.78930  ? 129 ALA A C   1 
ATOM   927  O O   . ALA A 1 134 ? 18.61475  -10.49930 -3.24069 1.000 48.72929  ? 129 ALA A O   1 
ATOM   928  C CB  . ALA A 1 134 ? 21.20615  -11.47349 -4.84030 1.000 47.06350  ? 129 ALA A CB  1 
ATOM   929  N N   . HIS A 1 135 ? 20.38181  -10.39623 -1.84302 1.000 46.28023  ? 130 HIS A N   1 
ATOM   930  C CA  . HIS A 1 135 ? 19.56750  -10.60744 -0.65347 1.000 44.35666  ? 130 HIS A CA  1 
ATOM   931  C C   . HIS A 1 135 ? 18.59656  -9.45490  -0.42962 1.000 44.48324  ? 130 HIS A C   1 
ATOM   932  O O   . HIS A 1 135 ? 17.39512  -9.67469  -0.24101 1.000 42.77690  ? 130 HIS A O   1 
ATOM   933  C CB  . HIS A 1 135 ? 20.47089  -10.79477 0.56312  1.000 43.78545  ? 130 HIS A CB  1 
ATOM   934  C CG  . HIS A 1 135 ? 19.73036  -10.82534 1.85946  1.000 44.64221  ? 130 HIS A CG  1 
ATOM   935  N ND1 . HIS A 1 135 ? 18.76958  -11.77099 2.14150  1.000 43.61449  ? 130 HIS A ND1 1 
ATOM   936  C CD2 . HIS A 1 135 ? 19.80861  -10.02835 2.95057  1.000 44.90216  ? 130 HIS A CD2 1 
ATOM   937  C CE1 . HIS A 1 135 ? 18.28741  -11.55712 3.35215  1.000 42.51226  ? 130 HIS A CE1 1 
ATOM   938  N NE2 . HIS A 1 135 ? 18.90056  -10.50475 3.86422  1.000 43.56375  ? 130 HIS A NE2 1 
ATOM   939  N N   . VAL A 1 136 ? 19.09634  -8.21626  -0.44158 1.000 44.42748  ? 131 VAL A N   1 
ATOM   940  C CA  . VAL A 1 136 ? 18.23283  -7.07856  -0.13408 1.000 50.51450  ? 131 VAL A CA  1 
ATOM   941  C C   . VAL A 1 136 ? 17.20990  -6.86642  -1.24112 1.000 52.34473  ? 131 VAL A C   1 
ATOM   942  O O   . VAL A 1 136 ? 16.07016  -6.46121  -0.98151 1.000 49.95922  ? 131 VAL A O   1 
ATOM   943  C CB  . VAL A 1 136 ? 19.06836  -5.80925  0.11804  1.000 53.05986  ? 131 VAL A CB  1 
ATOM   944  C CG1 . VAL A 1 136 ? 19.93399  -5.98693  1.35185  1.000 49.74708  ? 131 VAL A CG1 1 
ATOM   945  C CG2 . VAL A 1 136 ? 19.92066  -5.47166  -1.09053 1.000 54.62940  ? 131 VAL A CG2 1 
ATOM   946  N N   . ASP A 1 137 ? 17.59812  -7.12186  -2.49219 1.000 55.28463  ? 132 ASP A N   1 
ATOM   947  C CA  . ASP A 1 137 ? 16.62192  -7.08467  -3.57423 1.000 57.26902  ? 132 ASP A CA  1 
ATOM   948  C C   . ASP A 1 137 ? 15.54652  -8.14377  -3.36091 1.000 55.07657  ? 132 ASP A C   1 
ATOM   949  O O   . ASP A 1 137 ? 14.35453  -7.88261  -3.56512 1.000 55.07513  ? 132 ASP A O   1 
ATOM   950  C CB  . ASP A 1 137 ? 17.32218  -7.27214  -4.91941 1.000 60.81226  ? 132 ASP A CB  1 
ATOM   951  N N   . ASN A 1 138 ? 15.94781  -9.33572  -2.90958 1.000 51.01191  ? 133 ASN A N   1 
ATOM   952  C CA  . ASN A 1 138 ? 14.97744  -10.38292 -2.61297 1.000 51.52093  ? 133 ASN A CA  1 
ATOM   953  C C   . ASN A 1 138 ? 14.06921  -9.97423  -1.46205 1.000 50.78338  ? 133 ASN A C   1 
ATOM   954  O O   . ASN A 1 138 ? 12.86666  -10.26305 -1.47825 1.000 51.34561  ? 133 ASN A O   1 
ATOM   955  C CB  . ASN A 1 138 ? 15.70626  -11.68888 -2.28970 1.000 51.27496  ? 133 ASN A CB  1 
ATOM   956  C CG  . ASN A 1 138 ? 14.75884  -12.87138 -2.10578 1.000 50.66062  ? 133 ASN A CG  1 
ATOM   957  O OD1 . ASN A 1 138 ? 13.76203  -13.01217 -2.82000 1.000 47.28248  ? 133 ASN A OD1 1 
ATOM   958  N ND2 . ASN A 1 138 ? 15.07687  -13.73354 -1.14334 1.000 48.73942  ? 133 ASN A ND2 1 
ATOM   959  N N   . GLN A 1 139 ? 14.62663  -9.28624  -0.45909 1.000 48.69960  ? 134 GLN A N   1 
ATOM   960  C CA  . GLN A 1 139 ? 13.83573  -8.88460  0.70035  1.000 47.86073  ? 134 GLN A CA  1 
ATOM   961  C C   . GLN A 1 139 ? 12.76261  -7.87045  0.32531  1.000 51.94134  ? 134 GLN A C   1 
ATOM   962  O O   . GLN A 1 139 ? 11.62104  -7.97423  0.78962  1.000 55.38539  ? 134 GLN A O   1 
ATOM   963  C CB  . GLN A 1 139 ? 14.74101  -8.31320  1.79177  1.000 44.57339  ? 134 GLN A CB  1 
ATOM   964  C CG  . GLN A 1 139 ? 15.59022  -9.34125  2.51754  1.000 40.89711  ? 134 GLN A CG  1 
ATOM   965  C CD  . GLN A 1 139 ? 16.08012  -8.83892  3.86519  1.000 45.32033  ? 134 GLN A CD  1 
ATOM   966  O OE1 . GLN A 1 139 ? 16.14800  -9.59771  4.83608  1.000 44.90968  ? 134 GLN A OE1 1 
ATOM   967  N NE2 . GLN A 1 139 ? 16.42274  -7.55683  3.93352  1.000 46.01602  ? 134 GLN A NE2 1 
ATOM   968  N N   . ARG A 1 140 ? 13.11196  -6.86870  -0.48916 1.000 51.87676  ? 135 ARG A N   1 
ATOM   969  C CA  . ARG A 1 140 ? 12.12453  -5.86809  -0.88195 1.000 56.82550  ? 135 ARG A CA  1 
ATOM   970  C C   . ARG A 1 140 ? 10.93213  -6.51950  -1.56699 1.000 55.07984  ? 135 ARG A C   1 
ATOM   971  O O   . ARG A 1 140 ? 9.78516   -6.11194  -1.35282 1.000 60.02335  ? 135 ARG A O   1 
ATOM   972  C CB  . ARG A 1 140 ? 12.75852  -4.82241  -1.79909 1.000 64.70208  ? 135 ARG A CB  1 
ATOM   973  C CG  . ARG A 1 140 ? 13.95063  -4.09665  -1.20278 1.000 67.21412  ? 135 ARG A CG  1 
ATOM   974  C CD  . ARG A 1 140 ? 14.37933  -2.93372  -2.08434 1.000 74.14291  ? 135 ARG A CD  1 
ATOM   975  N NE  . ARG A 1 140 ? 15.82951  -2.87021  -2.24199 1.000 77.17908  ? 135 ARG A NE  1 
ATOM   976  C CZ  . ARG A 1 140 ? 16.48610  -3.32158  -3.30735 1.000 81.07184  ? 135 ARG A CZ  1 
ATOM   977  N NH1 . ARG A 1 140 ? 15.82216  -3.86626  -4.31986 1.000 83.15239  ? 135 ARG A NH1 1 
ATOM   978  N NH2 . ARG A 1 140 ? 17.80868  -3.22446  -3.36292 1.000 82.08259  ? 135 ARG A NH2 1 
ATOM   979  N N   . ARG A 1 141 ? 11.18483  -7.54295  -2.38741 1.000 54.50279  ? 136 ARG A N   1 
ATOM   980  C CA  . ARG A 1 141 ? 10.09550  -8.26118  -3.03972 1.000 61.75589  ? 136 ARG A CA  1 
ATOM   981  C C   . ARG A 1 141 ? 9.26945   -9.05874  -2.03865 1.000 56.18149  ? 136 ARG A C   1 
ATOM   982  O O   . ARG A 1 141 ? 8.06150   -9.23908  -2.23604 1.000 54.43654  ? 136 ARG A O   1 
ATOM   983  C CB  . ARG A 1 141 ? 10.65516  -9.17404  -4.13125 1.000 62.85782  ? 136 ARG A CB  1 
ATOM   984  C CG  . ARG A 1 141 ? 11.16758  -8.41263  -5.34897 1.000 71.45888  ? 136 ARG A CG  1 
ATOM   985  C CD  . ARG A 1 141 ? 11.72274  -9.34006  -6.42078 1.000 74.88654  ? 136 ARG A CD  1 
ATOM   986  N NE  . ARG A 1 141 ? 13.15029  -9.59611  -6.24495 1.000 75.49472  ? 136 ARG A NE  1 
ATOM   987  C CZ  . ARG A 1 141 ? 14.11409  -8.80419  -6.70776 1.000 78.86031  ? 136 ARG A CZ  1 
ATOM   988  N NH1 . ARG A 1 141 ? 13.80653  -7.69877  -7.37711 1.000 84.98416  ? 136 ARG A NH1 1 
ATOM   989  N NH2 . ARG A 1 141 ? 15.38613  -9.11914  -6.50404 1.000 74.57530  ? 136 ARG A NH2 1 
ATOM   990  N N   . VAL A 1 142 ? 9.89790   -9.54131  -0.96454 1.000 51.56587  ? 137 VAL A N   1 
ATOM   991  C CA  . VAL A 1 142 ? 9.15009   -10.21721 0.09022  1.000 46.25024  ? 137 VAL A CA  1 
ATOM   992  C C   . VAL A 1 142 ? 8.18615   -9.24877  0.76138  1.000 52.60048  ? 137 VAL A C   1 
ATOM   993  O O   . VAL A 1 142 ? 7.05890   -9.61616  1.11211  1.000 55.41748  ? 137 VAL A O   1 
ATOM   994  C CB  . VAL A 1 142 ? 10.11925  -10.85172 1.10578  1.000 42.40025  ? 137 VAL A CB  1 
ATOM   995  C CG1 . VAL A 1 142 ? 9.37197   -11.31099 2.33886  1.000 40.23145  ? 137 VAL A CG1 1 
ATOM   996  C CG2 . VAL A 1 142 ? 10.85781  -12.01666 0.46905  1.000 41.30950  ? 137 VAL A CG2 1 
ATOM   997  N N   . LEU A 1 143 ? 8.60594   -7.99542  0.93686  1.000 48.88301  ? 138 LEU A N   1 
ATOM   998  C CA  . LEU A 1 143 ? 7.81905   -6.98123  1.62794  1.000 54.12612  ? 138 LEU A CA  1 
ATOM   999  C C   . LEU A 1 143 ? 7.04858   -6.06998  0.68180  1.000 60.43407  ? 138 LEU A C   1 
ATOM   1000 O O   . LEU A 1 143 ? 6.49851   -5.05661  1.12824  1.000 65.16276  ? 138 LEU A O   1 
ATOM   1001 C CB  . LEU A 1 143 ? 8.72652   -6.13050  2.51287  1.000 53.65428  ? 138 LEU A CB  1 
ATOM   1002 C CG  . LEU A 1 143 ? 9.52017   -6.87296  3.58439  1.000 47.50593  ? 138 LEU A CG  1 
ATOM   1003 C CD1 . LEU A 1 143 ? 10.77350  -6.08425  3.89209  1.000 45.15616  ? 138 LEU A CD1 1 
ATOM   1004 C CD2 . LEU A 1 143 ? 8.67292   -7.06517  4.82810  1.000 49.45189  ? 138 LEU A CD2 1 
ATOM   1005 N N   . SER A 1 144 ? 6.99599   -6.40073  -0.60958 1.000 59.95470  ? 139 SER A N   1 
ATOM   1006 C CA  . SER A 1 144 ? 6.40530   -5.48238  -1.57934 1.000 63.95244  ? 139 SER A CA  1 
ATOM   1007 C C   . SER A 1 144 ? 4.91385   -5.28361  -1.33868 1.000 65.63301  ? 139 SER A C   1 
ATOM   1008 O O   . SER A 1 144 ? 4.36356   -4.23484  -1.69372 1.000 69.44700  ? 139 SER A O   1 
ATOM   1009 C CB  . SER A 1 144 ? 6.65636   -5.98897  -2.99986 1.000 63.19012  ? 139 SER A CB  1 
ATOM   1010 O OG  . SER A 1 144 ? 6.11281   -7.28402  -3.18011 1.000 62.09366  ? 139 SER A OG  1 
ATOM   1011 N N   . ALA A 1 145 ? 4.24618   -6.26834  -0.73319 1.000 64.01349  ? 140 ALA A N   1 
ATOM   1012 C CA  . ALA A 1 145 ? 2.82346   -6.15244  -0.43578 1.000 64.43911  ? 140 ALA A CA  1 
ATOM   1013 C C   . ALA A 1 145 ? 2.52930   -5.15125  0.67374  1.000 63.88730  ? 140 ALA A C   1 
ATOM   1014 O O   . ALA A 1 145 ? 1.37178   -4.74850  0.83168  1.000 66.50809  ? 140 ALA A O   1 
ATOM   1015 C CB  . ALA A 1 145 ? 2.25479   -7.52219  -0.05994 1.000 61.92976  ? 140 ALA A CB  1 
ATOM   1016 N N   . LEU A 1 146 ? 3.53262   -4.74729  1.44278  1.000 60.79013  ? 141 LEU A N   1 
ATOM   1017 C CA  . LEU A 1 146 ? 3.35941   -3.74920  2.48628  1.000 61.04949  ? 141 LEU A CA  1 
ATOM   1018 C C   . LEU A 1 146 ? 3.87551   -2.40212  2.00646  1.000 63.74081  ? 141 LEU A C   1 
ATOM   1019 O O   . LEU A 1 146 ? 4.92119   -2.32078  1.35690  1.000 65.11887  ? 141 LEU A O   1 
ATOM   1020 C CB  . LEU A 1 146 ? 4.09199   -4.15207  3.76856  1.000 57.19668  ? 141 LEU A CB  1 
ATOM   1021 C CG  . LEU A 1 146 ? 3.55853   -5.36773  4.52017  1.000 54.50101  ? 141 LEU A CG  1 
ATOM   1022 C CD1 . LEU A 1 146 ? 4.19328   -5.45291  5.90085  1.000 55.39172  ? 141 LEU A CD1 1 
ATOM   1023 C CD2 . LEU A 1 146 ? 2.04904   -5.29745  4.62584  1.000 55.37056  ? 141 LEU A CD2 1 
ATOM   1024 N N   . SER A 1 147 ? 3.13717   -1.34760  2.33170  1.000 66.78639  ? 142 SER A N   1 
ATOM   1025 C CA  . SER A 1 147 ? 3.60089   -0.00551  2.03222  1.000 71.21949  ? 142 SER A CA  1 
ATOM   1026 C C   . SER A 1 147 ? 4.80975   0.33779   2.89685  1.000 70.02499  ? 142 SER A C   1 
ATOM   1027 O O   . SER A 1 147 ? 5.10484   -0.32808  3.89115  1.000 68.41771  ? 142 SER A O   1 
ATOM   1028 C CB  . SER A 1 147 ? 2.48739   1.01081   2.26807  1.000 74.20384  ? 142 SER A CB  1 
ATOM   1029 O OG  . SER A 1 147 ? 2.16326   1.07094   3.64509  1.000 73.40468  ? 142 SER A OG  1 
ATOM   1030 N N   . ALA A 1 148 ? 5.51851   1.39685   2.49984  1.000 73.43442  ? 143 ALA A N   1 
ATOM   1031 C CA  . ALA A 1 148 ? 6.65663   1.85431   3.29006  1.000 71.54145  ? 143 ALA A CA  1 
ATOM   1032 C C   . ALA A 1 148 ? 6.23779   2.16377   4.72076  1.000 71.02479  ? 143 ALA A C   1 
ATOM   1033 O O   . ALA A 1 148 ? 6.97292   1.86762   5.66960  1.000 66.59756  ? 143 ALA A O   1 
ATOM   1034 C CB  . ALA A 1 148 ? 7.29369   3.08135   2.63795  1.000 71.68942  ? 143 ALA A CB  1 
ATOM   1035 N N   . ALA A 1 149 ? 5.05017   2.74788   4.89539  1.000 73.77108  ? 144 ALA A N   1 
ATOM   1036 C CA  . ALA A 1 149 ? 4.55815   3.03343   6.23820  1.000 74.14559  ? 144 ALA A CA  1 
ATOM   1037 C C   . ALA A 1 149 ? 4.15536   1.75490   6.96312  1.000 72.69716  ? 144 ALA A C   1 
ATOM   1038 O O   . ALA A 1 149 ? 4.38194   1.62383   8.17233  1.000 71.92071  ? 144 ALA A O   1 
ATOM   1039 C CB  . ALA A 1 149 ? 3.38423   4.00955   6.17060  1.000 77.19750  ? 144 ALA A CB  1 
ATOM   1040 N N   . GLU A 1 150 ? 3.55301   0.80254   6.24404  1.000 71.60277  ? 145 GLU A N   1 
ATOM   1041 C CA  . GLU A 1 150 ? 3.19953   -0.47319  6.85949  1.000 67.40727  ? 145 GLU A CA  1 
ATOM   1042 C C   . GLU A 1 150 ? 4.44213   -1.22619  7.31431  1.000 66.03247  ? 145 GLU A C   1 
ATOM   1043 O O   . GLU A 1 150 ? 4.44978   -1.83688  8.39033  1.000 64.35848  ? 145 GLU A O   1 
ATOM   1044 C CB  . GLU A 1 150 ? 2.38452   -1.32101  5.88398  1.000 67.22724  ? 145 GLU A CB  1 
ATOM   1045 C CG  . GLU A 1 150 ? 0.92124   -0.92121  5.78555  1.000 70.89736  ? 145 GLU A CG  1 
ATOM   1046 C CD  . GLU A 1 150 ? 0.24090   -1.50363  4.56071  1.000 71.81984  ? 145 GLU A CD  1 
ATOM   1047 O OE1 . GLU A 1 150 ? 0.92435   -1.69818  3.53332  1.000 71.68131  ? 145 GLU A OE1 1 
ATOM   1048 O OE2 . GLU A 1 150 ? -0.97660  -1.77067  4.62657  1.000 72.76467  ? 145 GLU A OE2 1 
ATOM   1049 N N   . GLN A 1 151 ? 5.50415   -1.19525  6.50717  1.000 66.18297  ? 146 GLN A N   1 
ATOM   1050 C CA  . GLN A 1 151 ? 6.74766   -1.84229  6.90740  1.000 63.07178  ? 146 GLN A CA  1 
ATOM   1051 C C   . GLN A 1 151 ? 7.32666   -1.18930  8.15413  1.000 63.92629  ? 146 GLN A C   1 
ATOM   1052 O O   . GLN A 1 151 ? 7.77012   -1.88271  9.07746  1.000 62.97520  ? 146 GLN A O   1 
ATOM   1053 C CB  . GLN A 1 151 ? 7.75610   -1.80001  5.75917  1.000 63.63809  ? 146 GLN A CB  1 
ATOM   1054 C CG  . GLN A 1 151 ? 7.30156   -2.52808  4.50783  1.000 63.58989  ? 146 GLN A CG  1 
ATOM   1055 C CD  . GLN A 1 151 ? 8.34004   -2.50083  3.40803  1.000 65.08679  ? 146 GLN A CD  1 
ATOM   1056 O OE1 . GLN A 1 151 ? 9.53818   -2.40467  3.67337  1.000 65.09370  ? 146 GLN A OE1 1 
ATOM   1057 N NE2 . GLN A 1 151 ? 7.88442   -2.57774  2.16142  1.000 64.51901  ? 146 GLN A NE2 1 
ATOM   1058 N N   . ARG A 1 152 ? 7.31855   0.14548   8.20500  1.000 64.93394  ? 147 ARG A N   1 
ATOM   1059 C CA  . ARG A 1 152 ? 7.87043   0.84401   9.36073  1.000 65.37006  ? 147 ARG A CA  1 
ATOM   1060 C C   . ARG A 1 152 ? 7.03327   0.59305   10.60821 1.000 64.14901  ? 147 ARG A C   1 
ATOM   1061 O O   . ARG A 1 152 ? 7.57949   0.41678   11.70328 1.000 63.43434  ? 147 ARG A O   1 
ATOM   1062 C CB  . ARG A 1 152 ? 7.97208   2.34139   9.06858  1.000 68.59289  ? 147 ARG A CB  1 
ATOM   1063 N N   . GLN A 1 153 ? 5.70625   0.57505   10.46305 1.000 64.26554  ? 148 GLN A N   1 
ATOM   1064 C CA  . GLN A 1 153 ? 4.84264   0.26346   11.59740 1.000 63.20748  ? 148 GLN A CA  1 
ATOM   1065 C C   . GLN A 1 153 ? 5.03898   -1.17680  12.05166 1.000 61.72134  ? 148 GLN A C   1 
ATOM   1066 O O   . GLN A 1 153 ? 4.99931   -1.46802  13.25361 1.000 63.33429  ? 148 GLN A O   1 
ATOM   1067 C CB  . GLN A 1 153 ? 3.38153   0.52256   11.22670 1.000 64.49612  ? 148 GLN A CB  1 
ATOM   1068 C CG  . GLN A 1 153 ? 2.41200   0.47055   12.39360 1.000 64.82282  ? 148 GLN A CG  1 
ATOM   1069 N N   . LEU A 1 154 ? 5.26220   -2.09096  11.10431 1.000 59.42429  ? 149 LEU A N   1 
ATOM   1070 C CA  . LEU A 1 154 ? 5.52137   -3.48002  11.46267 1.000 56.38079  ? 149 LEU A CA  1 
ATOM   1071 C C   . LEU A 1 154 ? 6.87040   -3.63775  12.15099 1.000 53.47959  ? 149 LEU A C   1 
ATOM   1072 O O   . LEU A 1 154 ? 7.01731   -4.48845  13.03392 1.000 50.48370  ? 149 LEU A O   1 
ATOM   1073 C CB  . LEU A 1 154 ? 5.44882   -4.36606  10.21952 1.000 57.79403  ? 149 LEU A CB  1 
ATOM   1074 C CG  . LEU A 1 154 ? 5.76847   -5.84801  10.41167 1.000 52.83239  ? 149 LEU A CG  1 
ATOM   1075 C CD1 . LEU A 1 154 ? 4.88573   -6.43415  11.48348 1.000 50.21063  ? 149 LEU A CD1 1 
ATOM   1076 C CD2 . LEU A 1 154 ? 5.58567   -6.59726  9.10660  1.000 52.84036  ? 149 LEU A CD2 1 
ATOM   1077 N N   . ALA A 1 155 ? 7.86258   -2.83413  11.76543 1.000 55.48388  ? 150 ALA A N   1 
ATOM   1078 C CA  . ALA A 1 155 ? 9.14302   -2.87268  12.45927 1.000 54.84695  ? 150 ALA A CA  1 
ATOM   1079 C C   . ALA A 1 155 ? 9.02826   -2.31174  13.87069 1.000 56.60237  ? 150 ALA A C   1 
ATOM   1080 O O   . ALA A 1 155 ? 9.73386   -2.76901  14.77604 1.000 56.47616  ? 150 ALA A O   1 
ATOM   1081 C CB  . ALA A 1 155 ? 10.19742  -2.10371  11.66488 1.000 55.31046  ? 150 ALA A CB  1 
ATOM   1082 N N   . LYS A 1 156 ? 8.15402   -1.32437  14.07647 1.000 58.51653  ? 151 LYS A N   1 
ATOM   1083 C CA  . LYS A 1 156 ? 7.95979   -0.77295  15.41344 1.000 61.33965  ? 151 LYS A CA  1 
ATOM   1084 C C   . LYS A 1 156 ? 7.28909   -1.78732  16.33069 1.000 60.32638  ? 151 LYS A C   1 
ATOM   1085 O O   . LYS A 1 156 ? 7.73841   -2.01076  17.46112 1.000 59.58451  ? 151 LYS A O   1 
ATOM   1086 C CB  . LYS A 1 156 ? 7.13392   0.51228   15.34132 1.000 63.49442  ? 151 LYS A CB  1 
ATOM   1087 C CG  . LYS A 1 156 ? 7.95112   1.77646   15.12192 1.000 66.81882  ? 151 LYS A CG  1 
ATOM   1088 N N   . LEU A 1 157 ? 6.20797   -2.41186  15.85802 1.000 59.37329  ? 152 LEU A N   1 
ATOM   1089 C CA  . LEU A 1 157 ? 5.49624   -3.38026  16.68312 1.000 57.60411  ? 152 LEU A CA  1 
ATOM   1090 C C   . LEU A 1 157 ? 6.38317   -4.56940  17.02718 1.000 56.46793  ? 152 LEU A C   1 
ATOM   1091 O O   . LEU A 1 157 ? 6.38003   -5.04468  18.16945 1.000 54.67979  ? 152 LEU A O   1 
ATOM   1092 C CB  . LEU A 1 157 ? 4.22404   -3.83649  15.97036 1.000 56.19096  ? 152 LEU A CB  1 
ATOM   1093 C CG  . LEU A 1 157 ? 3.17224   -2.74219  15.76881 1.000 58.96178  ? 152 LEU A CG  1 
ATOM   1094 C CD1 . LEU A 1 157 ? 2.08811   -3.20478  14.80925 1.000 59.96591  ? 152 LEU A CD1 1 
ATOM   1095 C CD2 . LEU A 1 157 ? 2.56666   -2.33302  17.09858 1.000 58.31100  ? 152 LEU A CD2 1 
ATOM   1096 N N   . LEU A 1 158 ? 7.16313   -5.05591  16.05673 1.000 56.96059  ? 153 LEU A N   1 
ATOM   1097 C CA  . LEU A 1 158 ? 8.04641   -6.18782  16.32617 1.000 54.53254  ? 153 LEU A CA  1 
ATOM   1098 C C   . LEU A 1 158 ? 9.12732   -5.82833  17.33690 1.000 54.23325  ? 153 LEU A C   1 
ATOM   1099 O O   . LEU A 1 158 ? 9.53054   -6.67710  18.14037 1.000 54.05904  ? 153 LEU A O   1 
ATOM   1100 C CB  . LEU A 1 158 ? 8.67895   -6.68898  15.02842 1.000 52.69124  ? 153 LEU A CB  1 
ATOM   1101 C CG  . LEU A 1 158 ? 7.75162   -7.44125  14.07178 1.000 51.66764  ? 153 LEU A CG  1 
ATOM   1102 C CD1 . LEU A 1 158 ? 8.46240   -7.72468  12.76493 1.000 49.76755  ? 153 LEU A CD1 1 
ATOM   1103 C CD2 . LEU A 1 158 ? 7.25737   -8.73807  14.70656 1.000 49.94112  ? 153 LEU A CD2 1 
ATOM   1104 N N   . ASP A 1 159 ? 9.60908   -4.58420  17.31529 1.000 56.00910  ? 154 ASP A N   1 
ATOM   1105 C CA  . ASP A 1 159 ? 10.58752  -4.15682  18.31103 1.000 57.92275  ? 154 ASP A CA  1 
ATOM   1106 C C   . ASP A 1 159 ? 9.97682   -4.15867  19.70596 1.000 56.76024  ? 154 ASP A C   1 
ATOM   1107 O O   . ASP A 1 159 ? 10.57770  -4.66495  20.65987 1.000 56.15450  ? 154 ASP A O   1 
ATOM   1108 C CB  . ASP A 1 159 ? 11.12428  -2.76702  17.96644 1.000 58.90639  ? 154 ASP A CB  1 
ATOM   1109 C CG  . ASP A 1 159 ? 12.24357  -2.33358  18.89287 1.000 59.58649  ? 154 ASP A CG  1 
ATOM   1110 O OD1 . ASP A 1 159 ? 12.90918  -3.21688  19.46839 1.000 60.07758  ? 154 ASP A OD1 1 
ATOM   1111 O OD2 . ASP A 1 159 ? 12.45463  -1.11589  19.05645 1.000 63.40743  ? 154 ASP A OD2 1 
ATOM   1112 N N   . LYS A 1 160 ? 8.77433   -3.59252  19.83774 1.000 57.67961  ? 155 LYS A N   1 
ATOM   1113 C CA  . LYS A 1 160 ? 8.09144   -3.56731  21.12756 1.000 59.68930  ? 155 LYS A CA  1 
ATOM   1114 C C   . LYS A 1 160 ? 7.83782   -4.97772  21.64316 1.000 58.05720  ? 155 LYS A C   1 
ATOM   1115 O O   . LYS A 1 160 ? 8.03844   -5.25940  22.82924 1.000 59.51834  ? 155 LYS A O   1 
ATOM   1116 C CB  . LYS A 1 160 ? 6.77772   -2.79495  20.99907 1.000 61.15469  ? 155 LYS A CB  1 
ATOM   1117 C CG  . LYS A 1 160 ? 6.36969   -2.01427  22.23030 1.000 65.00846  ? 155 LYS A CG  1 
ATOM   1118 C CD  . LYS A 1 160 ? 5.16701   -1.13008  21.93108 1.000 69.12303  ? 155 LYS A CD  1 
ATOM   1119 C CE  . LYS A 1 160 ? 4.97999   -0.05980  22.99663 1.000 73.30514  ? 155 LYS A CE  1 
ATOM   1120 N NZ  . LYS A 1 160 ? 4.75331   -0.65208  24.34483 1.000 75.32923  ? 155 LYS A NZ  1 
ATOM   1121 N N   . LEU A 1 161 ? 7.39892   -5.87892  20.76423 1.000 56.86853  ? 156 LEU A N   1 
ATOM   1122 C CA  . LEU A 1 161 ? 7.20515   -7.26817  21.16336 1.000 55.83966  ? 156 LEU A CA  1 
ATOM   1123 C C   . LEU A 1 161 ? 8.52721   -7.91463  21.55919 1.000 55.56376  ? 156 LEU A C   1 
ATOM   1124 O O   . LEU A 1 161 ? 8.58895   -8.68286  22.52792 1.000 51.13484  ? 156 LEU A O   1 
ATOM   1125 C CB  . LEU A 1 161 ? 6.54415   -8.04664  20.02433 1.000 53.96265  ? 156 LEU A CB  1 
ATOM   1126 C CG  . LEU A 1 161 ? 6.21688   -9.51804  20.27241 1.000 50.47358  ? 156 LEU A CG  1 
ATOM   1127 C CD1 . LEU A 1 161 ? 5.25643   -9.66505  21.44646 1.000 51.51694  ? 156 LEU A CD1 1 
ATOM   1128 C CD2 . LEU A 1 161 ? 5.63138   -10.13919 19.01606 1.000 45.73373  ? 156 LEU A CD2 1 
ATOM   1129 N N   . LEU A 1 162 ? 9.59943   -7.60366  20.82617 1.000 56.54099  ? 157 LEU A N   1 
ATOM   1130 C CA  . LEU A 1 162 ? 10.88720  -8.24299  21.07600 1.000 56.20922  ? 157 LEU A CA  1 
ATOM   1131 C C   . LEU A 1 162 ? 11.54070  -7.69891  22.34097 1.000 58.41011  ? 157 LEU A C   1 
ATOM   1132 O O   . LEU A 1 162 ? 12.17884  -8.45101  23.08763 1.000 59.14171  ? 157 LEU A O   1 
ATOM   1133 C CB  . LEU A 1 162 ? 11.79681  -8.05421  19.86101 1.000 56.90736  ? 157 LEU A CB  1 
ATOM   1134 C CG  . LEU A 1 162 ? 13.02543  -8.94962  19.71005 1.000 56.67736  ? 157 LEU A CG  1 
ATOM   1135 C CD1 . LEU A 1 162 ? 12.67326  -10.39843 19.99391 1.000 54.64508  ? 157 LEU A CD1 1 
ATOM   1136 C CD2 . LEU A 1 162 ? 13.59420  -8.80286  18.30550 1.000 55.87053  ? 157 LEU A CD2 1 
ATOM   1137 N N   . GLN A 1 163 ? 11.39483  -6.39462  22.59906 1.000 60.37657  ? 158 GLN A N   1 
ATOM   1138 C CA  . GLN A 1 163 ? 11.91068  -5.82523  23.84066 1.000 61.82881  ? 158 GLN A CA  1 
ATOM   1139 C C   . GLN A 1 163 ? 11.20167  -6.41727  25.05174 1.000 63.85449  ? 158 GLN A C   1 
ATOM   1140 O O   . GLN A 1 163 ? 11.82287  -6.63972  26.09719 1.000 66.27453  ? 158 GLN A O   1 
ATOM   1141 C CB  . GLN A 1 163 ? 11.76729  -4.30256  23.82717 1.000 62.04424  ? 158 GLN A CB  1 
ATOM   1142 C CG  . GLN A 1 163 ? 12.84107  -3.58079  23.02819 1.000 63.52086  ? 158 GLN A CG  1 
ATOM   1143 N N   . GLY A 1 164 ? 9.90457   -6.69276  24.92549 1.000 63.17761  ? 159 GLY A N   1 
ATOM   1144 C CA  . GLY A 1 164 ? 9.12492   -7.27283  26.00091 1.000 64.33725  ? 159 GLY A CA  1 
ATOM   1145 C C   . GLY A 1 164 ? 9.48620   -8.69316  26.38260 1.000 65.96696  ? 159 GLY A C   1 
ATOM   1146 O O   . GLY A 1 164 ? 8.87376   -9.23296  27.30975 1.000 68.38730  ? 159 GLY A O   1 
ATOM   1147 N N   . GLN A 1 165 ? 10.45385  -9.31333  25.70938 1.000 63.83628  ? 160 GLN A N   1 
ATOM   1148 C CA  . GLN A 1 165 ? 10.84953  -10.68731 26.02464 1.000 62.73098  ? 160 GLN A CA  1 
ATOM   1149 C C   . GLN A 1 165 ? 12.05754  -10.70751 26.95426 1.000 64.40483  ? 160 GLN A C   1 
ATOM   1150 O O   . GLN A 1 165 ? 12.12226  -9.94206  27.91183 1.000 67.58298  ? 160 GLN A O   1 
ATOM   1151 C CB  . GLN A 1 165 ? 11.16084  -11.47618 24.74822 1.000 58.22999  ? 160 GLN A CB  1 
ATOM   1152 C CG  . GLN A 1 165 ? 10.05878  -11.43349 23.69398 1.000 54.26941  ? 160 GLN A CG  1 
ATOM   1153 C CD  . GLN A 1 165 ? 8.71228   -11.88889 24.23038 1.000 54.06013  ? 160 GLN A CD  1 
ATOM   1154 O OE1 . GLN A 1 165 ? 8.56070   -13.02409 24.68658 1.000 54.25841  ? 160 GLN A OE1 1 
ATOM   1155 N NE2 . GLN A 1 165 ? 7.72586   -10.99940 24.18139 1.000 51.75470  ? 160 GLN A NE2 1 
HETATM 1156 N N1  . URC B 2 .   ? 21.38210  -8.60552  7.30830  1.000 50.10289  ? 201 URC A N1  1 
HETATM 1157 C C2  . URC B 2 .   ? 22.59318  -8.89617  7.89517  1.000 48.23741  ? 201 URC A C2  1 
HETATM 1158 C C6  . URC B 2 .   ? 20.33704  -9.51555  7.13439  1.000 49.86413  ? 201 URC A C6  1 
HETATM 1159 N N3  . URC B 2 .   ? 22.81064  -10.17126 8.35073  1.000 48.97608  ? 201 URC A N3  1 
HETATM 1160 O O11 . URC B 2 .   ? 23.46453  -8.04956  8.01369  1.000 46.84361  ? 201 URC A O11 1 
HETATM 1161 C C4  . URC B 2 .   ? 21.85061  -11.11932 8.22542  1.000 49.00238  ? 201 URC A C4  1 
HETATM 1162 C C5  . URC B 2 .   ? 20.61590  -10.81811 7.62653  1.000 51.78001  ? 201 URC A C5  1 
HETATM 1163 N N9  . URC B 2 .   ? 21.81761  -12.44448 8.58978  1.000 49.75347  ? 201 URC A N9  1 
HETATM 1164 O O13 . URC B 2 .   ? 19.28424  -9.15051  6.59577  1.000 45.48362  ? 201 URC A O13 1 
HETATM 1165 N N7  . URC B 2 .   ? 19.86902  -11.97209 7.64836  1.000 53.14317  ? 201 URC A N7  1 
HETATM 1166 C C8  . URC B 2 .   ? 20.60267  -12.96429 8.23773  1.000 50.31376  ? 201 URC A C8  1 
HETATM 1167 O O24 . URC B 2 .   ? 20.23454  -14.13015 8.41780  1.000 49.71718  ? 201 URC A O24 1 
HETATM 1168 O O   . HOH C 3 .   ? 2.14477   -19.55312 18.68211 1.000 40.04723  ? 301 HOH A O   1 
HETATM 1169 O O   . HOH C 3 .   ? 17.60352  -13.68065 0.57643  1.000 40.72941  ? 302 HOH A O   1 
HETATM 1170 O O   . HOH C 3 .   ? 17.58331  -12.77853 6.32598  1.000 40.04540  ? 303 HOH A O   1 
HETATM 1171 O O   . HOH C 3 .   ? 19.97132  -21.83009 2.49078  1.000 41.61795  ? 304 HOH A O   1 
HETATM 1172 O O   . HOH C 3 .   ? 6.81037   -22.83891 18.88123 1.000 41.52122  ? 305 HOH A O   1 
HETATM 1173 O O   . HOH C 3 .   ? 17.572    -15.205   7.331    1.000 38.00607  ? 306 HOH A O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . MET A 6   ? 0.97435 1.28457 0.86975 0.12081  -0.23114 0.07999  1   MET A N   
2    C CA  . MET A 6   ? 0.91047 1.18306 0.82923 0.14312  -0.19431 0.05486  1   MET A CA  
3    C C   . MET A 6   ? 0.88549 1.04480 0.73888 0.11534  -0.16974 0.03340  1   MET A C   
4    O O   . MET A 6   ? 0.89591 1.02668 0.69547 0.06341  -0.17141 0.02970  1   MET A O   
5    C CB  . MET A 6   ? 0.87940 1.23771 0.85055 0.13250  -0.18796 0.04797  1   MET A CB  
6    C CG  . MET A 6   ? 0.89036 1.33933 0.94547 0.18015  -0.18945 0.06232  1   MET A CG  
7    S SD  . MET A 6   ? 0.89233 1.40627 0.99813 0.17423  -0.16550 0.04623  1   MET A SD  
8    C CE  . MET A 6   ? 0.88874 1.49222 1.08926 0.23531  -0.16095 0.06745  1   MET A CE  
9    N N   . ASP A 7   ? 0.82564 0.92046 0.68651 0.14867  -0.14459 0.02024  2   ASP A N   
10   C CA  . ASP A 7   ? 0.80299 0.79908 0.61999 0.12804  -0.11899 0.00499  2   ASP A CA  
11   C C   . ASP A 7   ? 0.72069 0.73956 0.55131 0.10343  -0.10156 -0.00846 2   ASP A C   
12   O O   . ASP A 7   ? 0.67108 0.77706 0.53934 0.10035  -0.10851 -0.00839 2   ASP A O   
13   C CB  . ASP A 7   ? 0.79971 0.72582 0.62564 0.16967  -0.10224 -0.00136 2   ASP A CB  
14   C CG  . ASP A 7   ? 0.77428 0.73812 0.65506 0.20341  -0.09106 -0.01406 2   ASP A CG  
15   O OD1 . ASP A 7   ? 0.75996 0.81148 0.68095 0.21339  -0.09934 -0.01157 2   ASP A OD1 
16   O OD2 . ASP A 7   ? 0.76336 0.66815 0.64607 0.21803  -0.07308 -0.02622 2   ASP A OD2 
17   N N   . ARG A 8   ? 0.71420 0.65341 0.51714 0.08704  -0.07625 -0.01681 3   ARG A N   
18   C CA  . ARG A 8   ? 0.69218 0.64459 0.50408 0.06375  -0.05693 -0.02433 3   ARG A CA  
19   C C   . ARG A 8   ? 0.62375 0.63997 0.48823 0.09466  -0.05597 -0.03199 3   ARG A C   
20   O O   . ARG A 8   ? 0.61600 0.69261 0.49865 0.07956  -0.05217 -0.03451 3   ARG A O   
21   C CB  . ARG A 8   ? 0.70210 0.55825 0.48757 0.05067  -0.02834 -0.02487 3   ARG A CB  
22   C CG  . ARG A 8   ? 0.77162 0.54959 0.49768 0.01420  -0.01646 -0.01918 3   ARG A CG  
23   C CD  . ARG A 8   ? 0.77089 0.45452 0.48696 0.01046  0.01762  -0.01520 3   ARG A CD  
24   N NE  . ARG A 8   ? 0.80572 0.40463 0.46141 -0.02764 0.04006  -0.01062 3   ARG A NE  
25   C CZ  . ARG A 8   ? 0.87939 0.46155 0.50751 -0.07169 0.06412  -0.01039 3   ARG A CZ  
26   N NH1 . ARG A 8   ? 0.82197 0.47075 0.48151 -0.08100 0.06674  -0.01250 3   ARG A NH1 
27   N NH2 . ARG A 8   ? 1.01544 0.50855 0.58080 -0.10742 0.08972  -0.00869 3   ARG A NH2 
28   N N   . ALA A 9   ? 0.58825 0.58676 0.47347 0.13598  -0.05611 -0.03708 4   ALA A N   
29   C CA  . ALA A 9   ? 0.58931 0.62988 0.51050 0.16101  -0.04965 -0.04819 4   ALA A CA  
30   C C   . ALA A 9   ? 0.57862 0.71175 0.53680 0.17599  -0.05952 -0.04618 4   ALA A C   
31   O O   . ALA A 9   ? 0.54435 0.72858 0.52331 0.17469  -0.05031 -0.05258 4   ALA A O   
32   C CB  . ALA A 9   ? 0.60172 0.59059 0.52941 0.19526  -0.04466 -0.05706 4   ALA A CB  
33   N N   . ALA A 10  ? 0.53970 0.69673 0.50920 0.19135  -0.07671 -0.03403 5   ALA A N   
34   C CA  . ALA A 10  ? 0.55116 0.80201 0.56899 0.20885  -0.08479 -0.02540 5   ALA A CA  
35   C C   . ALA A 10  ? 0.55536 0.87263 0.57925 0.16888  -0.09234 -0.01898 5   ALA A C   
36   O O   . ALA A 10  ? 0.54608 0.93653 0.61204 0.17501  -0.08578 -0.01911 5   ALA A O   
37   C CB  . ALA A 10  ? 0.59627 0.86027 0.63003 0.23667  -0.10263 -0.00666 5   ALA A CB  
38   N N   . HIS A 11  ? 0.58422 0.87210 0.56482 0.12588  -0.10207 -0.01447 6   HIS A N   
39   C CA  . HIS A 11  ? 0.58774 0.92821 0.56797 0.08079  -0.10546 -0.01207 6   HIS A CA  
40   C C   . HIS A 11  ? 0.55295 0.89672 0.54007 0.07092  -0.07824 -0.02553 6   HIS A C   
41   O O   . HIS A 11  ? 0.53114 0.94722 0.54917 0.05685  -0.07485 -0.02448 6   HIS A O   
42   C CB  . HIS A 11  ? 0.63679 0.92274 0.55542 0.03303  -0.11315 -0.00934 6   HIS A CB  
43   C CG  . HIS A 11  ? 0.66201 0.99073 0.57242 -0.02028 -0.11362 -0.01012 6   HIS A CG  
44   N ND1 . HIS A 11  ? 0.67099 1.10503 0.62523 -0.03063 -0.13531 0.00034  6   HIS A ND1 
45   C CD2 . HIS A 11  ? 0.68427 0.96356 0.55137 -0.06709 -0.09188 -0.01918 6   HIS A CD2 
46   C CE1 . HIS A 11  ? 0.69197 1.13959 0.62734 -0.08460 -0.12894 -0.00528 6   HIS A CE1 
47   N NE2 . HIS A 11  ? 0.70483 1.05607 0.58492 -0.10713 -0.10051 -0.01772 6   HIS A NE2 
48   N N   . ALA A 12  ? 0.53726 0.80605 0.49849 0.07828  -0.05893 -0.03553 7   ALA A N   
49   C CA  . ALA A 12  ? 0.53600 0.80682 0.49993 0.07071  -0.03519 -0.04358 7   ALA A CA  
50   C C   . ALA A 12  ? 0.53213 0.86724 0.53857 0.10278  -0.02940 -0.04958 7   ALA A C   
51   O O   . ALA A 12  ? 0.54108 0.92545 0.56359 0.08995  -0.01634 -0.05097 7   ALA A O   
52   C CB  . ALA A 12  ? 0.52454 0.70895 0.45887 0.07436  -0.02107 -0.04703 7   ALA A CB  
53   N N   . VAL A 13  ? 0.52119 0.85040 0.54408 0.14431  -0.03391 -0.05363 8   VAL A N   
54   C CA  . VAL A 13  ? 0.54051 0.91905 0.59890 0.17565  -0.02132 -0.06075 8   VAL A CA  
55   C C   . VAL A 13  ? 0.53084 1.00249 0.63759 0.17295  -0.02551 -0.04862 8   VAL A C   
56   O O   . VAL A 13  ? 0.55494 1.07566 0.68783 0.17840  -0.00706 -0.05243 8   VAL A O   
57   C CB  . VAL A 13  ? 0.56258 0.90694 0.62738 0.21850  -0.02053 -0.06756 8   VAL A CB  
58   C CG1 . VAL A 13  ? 0.59418 0.99566 0.70395 0.25241  -0.00521 -0.06950 8   VAL A CG1 
59   C CG2 . VAL A 13  ? 0.56085 0.83152 0.58821 0.22037  -0.01102 -0.08359 8   VAL A CG2 
60   N N   . GLU A 14  ? 0.51369 1.01230 0.63300 0.16274  -0.05003 -0.03216 9   GLU A N   
61   C CA  . GLU A 14  ? 0.49234 1.08862 0.66377 0.15390  -0.06008 -0.01605 9   GLU A CA  
62   C C   . GLU A 14  ? 0.45934 1.08771 0.62877 0.11270  -0.04789 -0.02066 9   GLU A C   
63   O O   . GLU A 14  ? 0.42214 1.12725 0.64214 0.11575  -0.03781 -0.01554 9   GLU A O   
64   C CB  . GLU A 14  ? 0.52494 1.13954 0.69601 0.13969  -0.09483 0.00370  9   GLU A CB  
65   C CG  . GLU A 14  ? 0.55423 1.28033 0.78628 0.12861  -0.11328 0.02572  9   GLU A CG  
66   C CD  . GLU A 14  ? 0.60467 1.39263 0.91007 0.18232  -0.11056 0.04388  9   GLU A CD  
67   O OE1 . GLU A 14  ? 0.62429 1.35910 0.92223 0.22497  -0.09941 0.03950  9   GLU A OE1 
68   O OE2 . GLU A 14  ? 0.61544 1.50391 0.98960 0.18169  -0.11651 0.06370  9   GLU A OE2 
69   N N   . GLN A 15  ? 0.45818 1.02594 0.57298 0.07501  -0.04389 -0.02865 10  GLN A N   
70   C CA  . GLN A 15  ? 0.42942 1.01945 0.54024 0.03511  -0.02727 -0.03187 10  GLN A CA  
71   C C   . GLN A 15  ? 0.48633 1.08216 0.60638 0.05387  0.00356  -0.04153 10  GLN A C   
72   O O   . GLN A 15  ? 0.47841 1.12911 0.62497 0.03884  0.01944  -0.04048 10  GLN A O   
73   C CB  . GLN A 15  ? 0.46220 0.97616 0.51267 -0.00697 -0.02318 -0.03535 10  GLN A CB  
74   C CG  . GLN A 15  ? 0.49238 1.00295 0.52157 -0.04100 -0.04905 -0.02801 10  GLN A CG  
75   C CD  . GLN A 15  ? 0.53967 0.96807 0.50657 -0.08642 -0.03365 -0.03318 10  GLN A CD  
76   O OE1 . GLN A 15  ? 0.57375 0.92585 0.51148 -0.07774 -0.01208 -0.03705 10  GLN A OE1 
77   N NE2 . GLN A 15  ? 0.55428 0.99777 0.50192 -0.13692 -0.04274 -0.03203 10  GLN A NE2 
78   N N   . TRP A 16  ? 0.41338 0.95268 0.50924 0.08439  0.01225  -0.05101 11  TRP A N   
79   C CA  . TRP A 16  ? 0.49457 1.03273 0.58492 0.09879  0.03878  -0.06071 11  TRP A CA  
80   C C   . TRP A 16  ? 0.52005 1.12894 0.66060 0.12572  0.05165  -0.06134 11  TRP A C   
81   O O   . TRP A 16  ? 0.55691 1.19759 0.70604 0.11990  0.07588  -0.06375 11  TRP A O   
82   C CB  . TRP A 16  ? 0.49428 0.95956 0.54630 0.12085  0.03964  -0.07088 11  TRP A CB  
83   C CG  . TRP A 16  ? 0.47270 0.87490 0.48182 0.09518  0.04164  -0.06733 11  TRP A CG  
84   C CD1 . TRP A 16  ? 0.49971 0.83523 0.48437 0.09405  0.02935  -0.06507 11  TRP A CD1 
85   C CD2 . TRP A 16  ? 0.48751 0.88716 0.47923 0.06917  0.06139  -0.06157 11  TRP A CD2 
86   N NE1 . TRP A 16  ? 0.52862 0.82184 0.48658 0.06972  0.04098  -0.05660 11  TRP A NE1 
87   C CE2 . TRP A 16  ? 0.49590 0.82768 0.45708 0.05472  0.06047  -0.05342 11  TRP A CE2 
88   C CE3 . TRP A 16  ? 0.54066 0.98749 0.54246 0.05837  0.08313  -0.06018 11  TRP A CE3 
89   C CZ2 . TRP A 16  ? 0.52423 0.83606 0.46772 0.03156  0.08061  -0.04109 11  TRP A CZ2 
90   C CZ3 . TRP A 16  ? 0.56588 0.99038 0.54413 0.03434  0.10217  -0.05020 11  TRP A CZ3 
91   C CH2 . TRP A 16  ? 0.55340 0.91199 0.50418 0.02200  0.10081  -0.03944 11  TRP A CH2 
92   N N   . ARG A 17  ? 0.52774 1.15910 0.70372 0.15737  0.04012  -0.05682 12  ARG A N   
93   C CA  . ARG A 17  ? 0.55085 1.24821 0.78420 0.18654  0.05817  -0.05284 12  ARG A CA  
94   C C   . ARG A 17  ? 0.53539 1.31772 0.81838 0.16111  0.06104  -0.03914 12  ARG A C   
95   O O   . ARG A 17  ? 0.54545 1.37742 0.86968 0.17626  0.08802  -0.03771 12  ARG A O   
96   C CB  . ARG A 17  ? 0.59998 1.30871 0.87069 0.22443  0.04578  -0.04285 12  ARG A CB  
97   C CG  . ARG A 17  ? 0.68550 1.31890 0.92052 0.25772  0.05803  -0.06047 12  ARG A CG  
98   C CD  . ARG A 17  ? 0.74426 1.37378 1.00868 0.29214  0.04563  -0.04887 12  ARG A CD  
99   N NE  . ARG A 17  ? 0.81639 1.36674 1.04329 0.31858  0.06039  -0.06929 12  ARG A NE  
100  C CZ  . ARG A 17  ? 0.84879 1.36755 1.08414 0.34799  0.05468  -0.06491 12  ARG A CZ  
101  N NH1 . ARG A 17  ? 0.82124 1.38291 1.09929 0.35716  0.03218  -0.03750 12  ARG A NH1 
102  N NH2 . ARG A 17  ? 0.89773 1.33420 1.09360 0.35985  0.06985  -0.08566 12  ARG A NH2 
103  N N   . SER A 18  ? 0.50945 1.30514 0.78682 0.11976  0.03686  -0.03023 13  SER A N   
104  C CA  . SER A 18  ? 0.50566 1.37918 0.82648 0.08670  0.03837  -0.01973 13  SER A CA  
105  C C   . SER A 18  ? 0.54469 1.39793 0.83409 0.05873  0.06820  -0.03105 13  SER A C   
106  O O   . SER A 18  ? 0.56442 1.47796 0.89597 0.05158  0.08968  -0.02739 13  SER A O   
107  C CB  . SER A 18  ? 0.47837 1.37128 0.79818 0.04786  0.00086  -0.00779 13  SER A CB  
108  O OG  . SER A 18  ? 0.46117 1.41098 0.80464 0.00221  0.00355  -0.00366 13  SER A OG  
109  N N   . GLU A 19  ? 0.54068 1.31092 0.76116 0.04429  0.07225  -0.04145 14  GLU A N   
110  C CA  . GLU A 19  ? 0.51523 1.26391 0.70555 0.01649  0.09996  -0.04584 14  GLU A CA  
111  C C   . GLU A 19  ? 0.53991 1.26714 0.70933 0.04443  0.12969  -0.05413 14  GLU A C   
112  O O   . GLU A 19  ? 0.55385 1.29732 0.72218 0.03071  0.15826  -0.05347 14  GLU A O   
113  C CB  . GLU A 19  ? 0.47974 1.15227 0.61248 -0.01461 0.09367  -0.04638 14  GLU A CB  
114  C CG  . GLU A 19  ? 0.49642 1.18303 0.63258 -0.06082 0.07811  -0.04140 14  GLU A CG  
115  C CD  . GLU A 19  ? 0.52142 1.25557 0.68034 -0.09885 0.10080  -0.03991 14  GLU A CD  
116  O OE1 . GLU A 19  ? 0.51014 1.22923 0.65697 -0.09797 0.13450  -0.04121 14  GLU A OE1 
117  O OE2 . GLU A 19  ? 0.53183 1.31942 0.72006 -0.13118 0.08435  -0.03643 14  GLU A OE2 
118  N N   . ARG A 20  ? 0.55372 1.24205 0.70170 0.08047  0.12476  -0.06242 15  ARG A N   
119  C CA  . ARG A 20  ? 0.60416 1.26559 0.71902 0.10259  0.14943  -0.07299 15  ARG A CA  
120  C C   . ARG A 20  ? 0.58754 1.26039 0.72457 0.14453  0.15424  -0.08191 15  ARG A C   
121  O O   . ARG A 20  ? 0.58318 1.20267 0.68602 0.16496  0.14670  -0.09295 15  ARG A O   
122  C CB  . ARG A 20  ? 0.63812 1.22257 0.68861 0.09638  0.14198  -0.07589 15  ARG A CB  
123  C CG  . ARG A 20  ? 0.65171 1.21671 0.67933 0.06001  0.14957  -0.06369 15  ARG A CG  
124  C CD  . ARG A 20  ? 0.66768 1.25535 0.68606 0.05303  0.18265  -0.06067 15  ARG A CD  
125  N NE  . ARG A 20  ? 0.72738 1.29719 0.70988 0.07874  0.19295  -0.07054 15  ARG A NE  
126  C CZ  . ARG A 20  ? 0.73595 1.25815 0.66463 0.07765  0.19057  -0.06705 15  ARG A CZ  
127  N NH1 . ARG A 20  ? 0.70427 1.19233 0.61795 0.05697  0.18207  -0.05035 15  ARG A NH1 
128  N NH2 . ARG A 20  ? 0.77938 1.28776 0.66912 0.09584  0.19802  -0.07886 15  ARG A NH2 
129  N N   . PRO A 21  ? 0.58773 1.32854 0.78574 0.15794  0.17069  -0.07635 16  PRO A N   
130  C CA  . PRO A 21  ? 0.61485 1.36362 0.84107 0.20077  0.18379  -0.08143 16  PRO A CA  
131  C C   . PRO A 21  ? 0.68493 1.38053 0.85531 0.21994  0.21455  -0.10201 16  PRO A C   
132  O O   . PRO A 21  ? 0.74402 1.41381 0.91765 0.25087  0.22597  -0.11058 16  PRO A O   
133  C CB  . PRO A 21  ? 0.60569 1.44556 0.91719 0.20594  0.19982  -0.06501 16  PRO A CB  
134  C CG  . PRO A 21  ? 0.59527 1.45988 0.90136 0.16814  0.21065  -0.06156 16  PRO A CG  
135  C CD  . PRO A 21  ? 0.57487 1.38728 0.82325 0.13477  0.18289  -0.06394 16  PRO A CD  
136  N N   . ASP A 22  ? 0.70389 1.37320 0.81856 0.19863  0.22772  -0.10826 17  ASP A N   
137  C CA  . ASP A 22  ? 0.77234 1.37520 0.81696 0.20556  0.24568  -0.12565 17  ASP A CA  
138  C C   . ASP A 22  ? 0.80231 1.34692 0.79507 0.21225  0.22244  -0.13991 17  ASP A C   
139  O O   . ASP A 22  ? 0.85003 1.33984 0.78519 0.21660  0.23300  -0.15673 17  ASP A O   
140  C CB  . ASP A 22  ? 0.78537 1.37492 0.78465 0.17821  0.25909  -0.12114 17  ASP A CB  
141  C CG  . ASP A 22  ? 0.74102 1.33639 0.73112 0.14953  0.23612  -0.10740 17  ASP A CG  
142  O OD1 . ASP A 22  ? 0.68983 1.33185 0.73322 0.13883  0.22502  -0.09617 17  ASP A OD1 
143  O OD2 . ASP A 22  ? 0.75697 1.30902 0.68699 0.13583  0.22995  -0.10605 17  ASP A OD2 
144  N N   . LEU A 23  ? 0.77003 1.30718 0.78013 0.20461  0.18704  -0.13046 18  LEU A N   
145  C CA  . LEU A 23  ? 0.78491 1.25898 0.75482 0.20520  0.16137  -0.13861 18  LEU A CA  
146  C C   . LEU A 23  ? 0.78363 1.24431 0.78178 0.23587  0.15645  -0.14641 18  LEU A C   
147  O O   . LEU A 23  ? 0.77357 1.28125 0.83333 0.25232  0.15966  -0.13568 18  LEU A O   
148  C CB  . LEU A 23  ? 0.77653 1.23857 0.74520 0.17823  0.13193  -0.12186 18  LEU A CB  
149  C CG  . LEU A 23  ? 0.80184 1.24239 0.72650 0.15044  0.13124  -0.11282 18  LEU A CG  
150  C CD1 . LEU A 23  ? 0.75877 1.17504 0.68891 0.12980  0.10847  -0.09654 18  LEU A CD1 
151  C CD2 . LEU A 23  ? 0.86972 1.26570 0.73535 0.15497  0.13138  -0.12603 18  LEU A CD2 
152  N N   . ASP A 24  ? 0.80840 1.20623 0.76370 0.24248  0.14790  -0.16257 19  ASP A N   
153  C CA  . ASP A 24  ? 0.83305 1.20302 0.80815 0.26910  0.14212  -0.16940 19  ASP A CA  
154  C C   . ASP A 24  ? 0.78220 1.11384 0.74673 0.25534  0.10648  -0.16189 19  ASP A C   
155  O O   . ASP A 24  ? 0.78988 1.06675 0.70972 0.24690  0.09683  -0.17393 19  ASP A O   
156  C CB  . ASP A 24  ? 0.95504 1.27207 0.88976 0.28341  0.16611  -0.19576 19  ASP A CB  
157  C CG  . ASP A 24  ? 1.03384 1.30347 0.98464 0.30162  0.16020  -0.19961 19  ASP A CG  
158  O OD1 . ASP A 24  ? 1.04525 1.34334 1.05573 0.32135  0.15856  -0.18185 19  ASP A OD1 
159  O OD2 . ASP A 24  ? 1.09457 1.30030 0.99930 0.29349  0.15670  -0.21813 19  ASP A OD2 
160  N N   . PRO A 25  ? 0.82135 1.17160 0.80740 0.20469  0.14974  -0.07951 20  PRO A N   
161  C CA  . PRO A 25  ? 0.79890 1.08988 0.77023 0.19488  0.13195  -0.06520 20  PRO A CA  
162  C C   . PRO A 25  ? 0.74095 1.00725 0.71652 0.21653  0.10085  -0.07562 20  PRO A C   
163  O O   . PRO A 25  ? 0.70715 0.93998 0.68150 0.20674  0.08510  -0.06729 20  PRO A O   
164  C CB  . PRO A 25  ? 0.59105 0.89728 0.59307 0.16313  0.14263  -0.06001 20  PRO A CB  
165  C CG  . PRO A 25  ? 0.76148 1.14148 0.80597 0.16735  0.14686  -0.07893 20  PRO A CG  
166  C CD  . PRO A 25  ? 0.78762 1.19504 0.82123 0.19081  0.15889  -0.08758 20  PRO A CD  
167  N N   . SER A 26  ? 0.72643 1.00677 0.70809 0.24540  0.09465  -0.09374 21  SER A N   
168  C CA  . SER A 26  ? 0.75527 1.01027 0.74842 0.26744  0.06929  -0.10019 21  SER A CA  
169  C C   . SER A 26  ? 0.75830 0.94752 0.71629 0.26293  0.05296  -0.09051 21  SER A C   
170  O O   . SER A 26  ? 0.80012 0.96492 0.76581 0.26423  0.03275  -0.08362 21  SER A O   
171  C CB  . SER A 26  ? 0.78550 1.05544 0.79252 0.29982  0.07286  -0.12289 21  SER A CB  
172  O OG  . SER A 26  ? 0.84076 1.11717 0.81862 0.29945  0.09206  -0.13542 21  SER A OG  
173  N N   . SER A 27  ? 0.71936 0.88752 0.63880 0.25681  0.06154  -0.08793 22  SER A N   
174  C CA  . SER A 27  ? 0.71534 0.83150 0.60355 0.25371  0.04660  -0.08087 22  SER A CA  
175  C C   . SER A 27  ? 0.65822 0.74927 0.54638 0.23326  0.03904  -0.05996 22  SER A C   
176  O O   . SER A 27  ? 0.64429 0.69537 0.51504 0.23157  0.02401  -0.05471 22  SER A O   
177  C CB  . SER A 27  ? 0.76361 0.88219 0.61256 0.25150  0.05781  -0.08018 22  SER A CB  
178  O OG  . SER A 27  ? 0.78919 0.92716 0.63105 0.23505  0.07688  -0.05785 22  SER A OG  
179  N N   . MET A 28  ? 0.63238 0.74765 0.54152 0.21548  0.05132  -0.05157 23  MET A N   
180  C CA  . MET A 28  ? 0.62937 0.72034 0.54019 0.19303  0.04965  -0.03816 23  MET A CA  
181  C C   . MET A 28  ? 0.60134 0.68071 0.52405 0.19442  0.02536  -0.04209 23  MET A C   
182  O O   . MET A 28  ? 0.58702 0.63442 0.49929 0.18162  0.01861  -0.03440 23  MET A O   
183  C CB  . MET A 28  ? 0.61830 0.73883 0.55328 0.16912  0.07234  -0.03531 23  MET A CB  
184  C CG  . MET A 28  ? 0.63598 0.76037 0.55803 0.16231  0.10068  -0.02185 23  MET A CG  
185  S SD  . MET A 28  ? 0.61221 0.76785 0.57060 0.12915  0.13054  -0.02232 23  MET A SD  
186  C CE  . MET A 28  ? 0.66304 0.79982 0.59805 0.12309  0.16457  0.00729  23  MET A CE  
187  N N   . ILE A 29  ? 0.60019 0.70814 0.54584 0.21120  0.01341  -0.05150 24  ILE A N   
188  C CA  . ILE A 29  ? 0.60337 0.71165 0.56181 0.21282  -0.00858 -0.04820 24  ILE A CA  
189  C C   . ILE A 29  ? 0.61936 0.67170 0.55128 0.21987  -0.02446 -0.04239 24  ILE A C   
190  O O   . ILE A 29  ? 0.62672 0.66103 0.55054 0.20479  -0.03406 -0.03493 24  ILE A O   
191  C CB  . ILE A 29  ? 0.62146 0.77555 0.61339 0.23621  -0.01674 -0.05253 24  ILE A CB  
192  C CG1 . ILE A 29  ? 0.60203 0.82433 0.62488 0.22306  -0.00284 -0.05923 24  ILE A CG1 
193  C CG2 . ILE A 29  ? 0.61923 0.77255 0.61981 0.24413  -0.04093 -0.04090 24  ILE A CG2 
194  C CD1 . ILE A 29  ? 0.61795 0.89631 0.67832 0.25037  -0.00755 -0.06322 24  ILE A CD1 
195  N N   . VAL A 30  ? 0.66676 0.69410 0.58563 0.23997  -0.02532 -0.04927 25  VAL A N   
196  C CA  . VAL A 30  ? 0.69891 0.67715 0.59800 0.24475  -0.03955 -0.04741 25  VAL A CA  
197  C C   . VAL A 30  ? 0.66772 0.61936 0.53818 0.22504  -0.03791 -0.04062 25  VAL A C   
198  O O   . VAL A 30  ? 0.67602 0.60141 0.53772 0.21670  -0.05030 -0.03339 25  VAL A O   
199  C CB  . VAL A 30  ? 0.75233 0.71265 0.64822 0.26671  -0.03676 -0.06404 25  VAL A CB  
200  C CG1 . VAL A 30  ? 0.76205 0.74500 0.64478 0.26676  -0.01801 -0.07719 25  VAL A CG1 
201  C CG2 . VAL A 30  ? 0.76170 0.67096 0.63672 0.26470  -0.04758 -0.06636 25  VAL A CG2 
202  N N   . LEU A 31  ? 0.58354 0.54510 0.44094 0.21866  -0.02147 -0.03978 26  LEU A N   
203  C CA  . LEU A 31  ? 0.59204 0.53201 0.42719 0.20602  -0.01851 -0.02831 26  LEU A CA  
204  C C   . LEU A 31  ? 0.58152 0.51864 0.42877 0.18615  -0.01338 -0.01779 26  LEU A C   
205  O O   . LEU A 31  ? 0.57365 0.48609 0.41033 0.17755  -0.01599 -0.00999 26  LEU A O   
206  C CB  . LEU A 31  ? 0.60486 0.56008 0.42179 0.20926  -0.00187 -0.02394 26  LEU A CB  
207  C CG  . LEU A 31  ? 0.60457 0.56750 0.40158 0.22346  -0.00495 -0.03959 26  LEU A CG  
208  C CD1 . LEU A 31  ? 0.58589 0.57976 0.36301 0.22476  0.01244  -0.03120 26  LEU A CD1 
209  C CD2 . LEU A 31  ? 0.59449 0.52967 0.37423 0.22262  -0.02165 -0.04488 26  LEU A CD2 
210  N N   . GLY A 32  ? 0.56525 0.53101 0.43676 0.17706  -0.00415 -0.02088 27  GLY A N   
211  C CA  . GLY A 32  ? 0.57593 0.54219 0.46143 0.15359  0.00162  -0.01987 27  GLY A CA  
212  C C   . GLY A 32  ? 0.56155 0.52404 0.44813 0.14959  -0.01971 -0.02282 27  GLY A C   
213  O O   . GLY A 32  ? 0.52667 0.47268 0.40992 0.13300  -0.01848 -0.02221 27  GLY A O   
214  N N   . ARG A 33  ? 0.58152 0.55909 0.47365 0.16606  -0.03753 -0.02440 28  ARG A N   
215  C CA  . ARG A 33  ? 0.62164 0.59583 0.51188 0.16473  -0.05759 -0.01982 28  ARG A CA  
216  C C   . ARG A 33  ? 0.65240 0.57918 0.51778 0.16718  -0.06553 -0.01453 28  ARG A C   
217  O O   . ARG A 33  ? 0.65115 0.57025 0.51013 0.15560  -0.07492 -0.01029 28  ARG A O   
218  C CB  . ARG A 33  ? 0.59113 0.59128 0.49833 0.18618  -0.07174 -0.01591 28  ARG A CB  
219  C CG  . ARG A 33  ? 0.56954 0.63393 0.50535 0.18049  -0.06935 -0.01978 28  ARG A CG  
220  C CD  . ARG A 33  ? 0.57744 0.67361 0.53387 0.20618  -0.08559 -0.00907 28  ARG A CD  
221  N NE  . ARG A 33  ? 0.52142 0.69363 0.50824 0.20110  -0.08407 -0.01353 28  ARG A NE  
222  C CZ  . ARG A 33  ? 0.50845 0.72452 0.52407 0.22785  -0.09043 -0.00702 28  ARG A CZ  
223  N NH1 . ARG A 33  ? 0.53181 0.71300 0.55065 0.26245  -0.09605 0.00349  28  ARG A NH1 
224  N NH2 . ARG A 33  ? 0.50179 0.79811 0.54661 0.21952  -0.08917 -0.01284 28  ARG A NH2 
225  N N   . LEU A 34  ? 0.62312 0.52589 0.47420 0.17982  -0.06147 -0.01651 29  LEU A N   
226  C CA  . LEU A 34  ? 0.60683 0.47519 0.43649 0.17856  -0.06799 -0.01447 29  LEU A CA  
227  C C   . LEU A 34  ? 0.60954 0.47061 0.43333 0.16127  -0.06000 -0.00933 29  LEU A C   
228  O O   . LEU A 34  ? 0.61542 0.46148 0.43186 0.15248  -0.06818 -0.00679 29  LEU A O   
229  C CB  . LEU A 34  ? 0.65055 0.51069 0.46624 0.19190  -0.06376 -0.02191 29  LEU A CB  
230  C CG  . LEU A 34  ? 0.65440 0.49314 0.44891 0.18854  -0.06957 -0.02337 29  LEU A CG  
231  C CD1 . LEU A 34  ? 0.71237 0.52481 0.50648 0.18950  -0.08364 -0.02878 29  LEU A CD1 
232  C CD2 . LEU A 34  ? 0.69258 0.54490 0.47146 0.19671  -0.06185 -0.03079 29  LEU A CD2 
233  N N   . GLN A 35  ? 0.59568 0.46573 0.42532 0.15663  -0.04114 -0.00702 30  GLN A N   
234  C CA  . GLN A 35  ? 0.60079 0.45650 0.43065 0.14463  -0.02832 -0.00089 30  GLN A CA  
235  C C   . GLN A 35  ? 0.56656 0.42742 0.41015 0.12380  -0.02703 -0.00885 30  GLN A C   
236  O O   . GLN A 35  ? 0.54308 0.38900 0.38405 0.11465  -0.02555 -0.00904 30  GLN A O   
237  C CB  . GLN A 35  ? 0.62076 0.47833 0.45605 0.14663  -0.00443 0.00831  30  GLN A CB  
238  C CG  . GLN A 35  ? 0.68514 0.54857 0.50140 0.16552  -0.00480 0.01762  30  GLN A CG  
239  C CD  . GLN A 35  ? 0.72984 0.59702 0.54868 0.16829  0.02012  0.03543  30  GLN A CD  
240  O OE1 . GLN A 35  ? 0.77579 0.63004 0.59189 0.17240  0.03020  0.05395  30  GLN A OE1 
241  N NE2 . GLN A 35  ? 0.72588 0.61273 0.55225 0.16740  0.03161  0.03281  30  GLN A NE2 
242  N N   . GLU A 36  ? 0.57091 0.46096 0.42996 0.11525  -0.02710 -0.01755 31  GLU A N   
243  C CA  . GLU A 36  ? 0.58194 0.49123 0.45215 0.09162  -0.02612 -0.02933 31  GLU A CA  
244  C C   . GLU A 36  ? 0.58931 0.50064 0.44589 0.09095  -0.04825 -0.02638 31  GLU A C   
245  O O   . GLU A 36  ? 0.62643 0.53982 0.48159 0.07230  -0.04546 -0.03406 31  GLU A O   
246  C CB  . GLU A 36  ? 0.58289 0.53861 0.47359 0.08204  -0.02348 -0.03958 31  GLU A CB  
247  C CG  . GLU A 36  ? 0.63371 0.62636 0.53534 0.05342  -0.02313 -0.05665 31  GLU A CG  
248  C CD  . GLU A 36  ? 0.68335 0.65647 0.59671 0.02690  0.00580  -0.07377 31  GLU A CD  
249  O OE1 . GLU A 36  ? 0.70678 0.63311 0.61987 0.03482  0.02459  -0.06512 31  GLU A OE1 
250  O OE2 . GLU A 36  ? 0.69047 0.69768 0.61484 -0.00182 0.01112  -0.09605 31  GLU A OE2 
251  N N   . ALA A 37  ? 0.58717 0.49638 0.43488 0.11025  -0.06740 -0.01577 32  ALA A N   
252  C CA  . ALA A 37  ? 0.61207 0.51712 0.44735 0.10960  -0.08564 -0.00759 32  ALA A CA  
253  C C   . ALA A 37  ? 0.61663 0.48823 0.43690 0.10416  -0.08314 -0.00695 32  ALA A C   
254  O O   . ALA A 37  ? 0.56751 0.44408 0.38108 0.08938  -0.08736 -0.00719 32  ALA A O   
255  C CB  . ALA A 37  ? 0.60907 0.50706 0.44360 0.13274  -0.10088 0.00426  32  ALA A CB  
256  N N   . ALA A 38  ? 0.56488 0.41118 0.38001 0.11567  -0.07612 -0.00599 33  ALA A N   
257  C CA  . ALA A 38  ? 0.57112 0.39761 0.37640 0.11230  -0.07393 -0.00456 33  ALA A CA  
258  C C   . ALA A 38  ? 0.55995 0.38987 0.37490 0.09621  -0.05749 -0.01112 33  ALA A C   
259  O O   . ALA A 38  ? 0.59125 0.41719 0.40209 0.08715  -0.05822 -0.01284 33  ALA A O   
260  C CB  . ALA A 38  ? 0.60696 0.42200 0.40573 0.12826  -0.06985 -0.00100 33  ALA A CB  
261  N N   . LEU A 39  ? 0.54880 0.38511 0.37937 0.09110  -0.03953 -0.01711 34  LEU A N   
262  C CA  . LEU A 39  ? 0.56779 0.39897 0.41305 0.07486  -0.01768 -0.02784 34  LEU A CA  
263  C C   . LEU A 39  ? 0.59774 0.45421 0.44326 0.05072  -0.02204 -0.04421 34  LEU A C   
264  O O   . LEU A 39  ? 0.60386 0.45612 0.45113 0.03877  -0.01343 -0.05363 34  LEU A O   
265  C CB  . LEU A 39  ? 0.58108 0.40726 0.44555 0.07244  0.00655  -0.03071 34  LEU A CB  
266  C CG  . LEU A 39  ? 0.61451 0.43069 0.50165 0.05084  0.03542  -0.04826 34  LEU A CG  
267  C CD1 . LEU A 39  ? 0.61518 0.40090 0.50779 0.05932  0.04925  -0.04168 34  LEU A CD1 
268  C CD2 . LEU A 39  ? 0.63117 0.44075 0.53893 0.04463  0.06048  -0.05069 34  LEU A CD2 
269  N N   . VAL A 40  ? 0.59095 0.48137 0.43524 0.04418  -0.03510 -0.04727 35  VAL A N   
270  C CA  . VAL A 40  ? 0.59551 0.52577 0.43789 0.02010  -0.03997 -0.06120 35  VAL A CA  
271  C C   . VAL A 40  ? 0.58823 0.51858 0.40998 0.02010  -0.05693 -0.05061 35  VAL A C   
272  O O   . VAL A 40  ? 0.61104 0.55914 0.42880 -0.00075 -0.05148 -0.06407 35  VAL A O   
273  C CB  . VAL A 40  ? 0.55713 0.53638 0.40526 0.01705  -0.05204 -0.06155 35  VAL A CB  
274  C CG1 . VAL A 40  ? 0.59785 0.63274 0.43705 -0.00397 -0.06450 -0.06793 35  VAL A CG1 
275  C CG2 . VAL A 40  ? 0.53719 0.52544 0.40901 0.00564  -0.03006 -0.07944 35  VAL A CG2 
276  N N   . ILE A 41  ? 0.52990 0.44051 0.33926 0.04095  -0.07484 -0.02885 36  ILE A N   
277  C CA  . ILE A 41  ? 0.56670 0.47281 0.35842 0.03854  -0.08839 -0.01701 36  ILE A CA  
278  C C   . ILE A 41  ? 0.59712 0.48345 0.38828 0.03134  -0.07543 -0.02596 36  ILE A C   
279  O O   . ILE A 41  ? 0.61672 0.51924 0.39970 0.01436  -0.07509 -0.03048 36  ILE A O   
280  C CB  . ILE A 41  ? 0.60883 0.48996 0.39298 0.06007  -0.10498 0.00363  36  ILE A CB  
281  C CG1 . ILE A 41  ? 0.63885 0.54574 0.42720 0.06933  -0.11790 0.01613  36  ILE A CG1 
282  C CG2 . ILE A 41  ? 0.61661 0.48159 0.38579 0.05467  -0.11318 0.01435  36  ILE A CG2 
283  C CD1 . ILE A 41  ? 0.65959 0.53479 0.44798 0.09319  -0.12830 0.03230  36  ILE A CD1 
284  N N   . ALA A 42  ? 0.56252 0.42051 0.36350 0.04518  -0.06372 -0.02715 37  ALA A N   
285  C CA  . ALA A 42  ? 0.57545 0.42158 0.38256 0.04349  -0.05013 -0.03275 37  ALA A CA  
286  C C   . ALA A 42  ? 0.62885 0.48906 0.44883 0.02306  -0.02943 -0.05455 37  ALA A C   
287  O O   . ALA A 42  ? 0.63514 0.50450 0.45360 0.01150  -0.02459 -0.06278 37  ALA A O   
288  C CB  . ALA A 42  ? 0.54752 0.37113 0.36490 0.06499  -0.04047 -0.02485 37  ALA A CB  
289  N N   . ARG A 43  ? 0.63099 0.49542 0.46527 0.01567  -0.01483 -0.06780 38  ARG A N   
290  C CA  . ARG A 43  ? 0.60099 0.47126 0.45329 -0.00564 0.01185  -0.09568 38  ARG A CA  
291  C C   . ARG A 43  ? 0.63299 0.54962 0.47159 -0.03392 0.00481  -0.11366 38  ARG A C   
292  O O   . ARG A 43  ? 0.59027 0.51539 0.43356 -0.05031 0.02067  -0.13470 38  ARG A O   
293  C CB  . ARG A 43  ? 0.61562 0.47638 0.48907 -0.00999 0.03186  -0.10671 38  ARG A CB  
294  C CG  . ARG A 43  ? 0.65630 0.51246 0.55458 -0.03411 0.06609  -0.14040 38  ARG A CG  
295  C CD  . ARG A 43  ? 0.68865 0.54169 0.60676 -0.04576 0.08415  -0.15298 38  ARG A CD  
296  N NE  . ARG A 43  ? 0.74216 0.65192 0.64742 -0.06387 0.06335  -0.16202 38  ARG A NE  
297  C CZ  . ARG A 43  ? 0.81052 0.73299 0.72045 -0.06003 0.05737  -0.15414 38  ARG A CZ  
298  N NH1 . ARG A 43  ? 0.77635 0.65682 0.69944 -0.04116 0.07127  -0.13735 38  ARG A NH1 
299  N NH2 . ARG A 43  ? 0.85939 0.84324 0.76123 -0.07378 0.03751  -0.16075 38  ARG A NH2 
300  N N   . ASP A 44  ? 0.64746 0.59993 0.47006 -0.03874 -0.01781 -0.10475 39  ASP A N   
301  C CA  . ASP A 44  ? 0.70270 0.71411 0.51154 -0.06558 -0.02519 -0.11817 39  ASP A CA  
302  C C   . ASP A 44  ? 0.68579 0.71524 0.46708 -0.06350 -0.04881 -0.09370 39  ASP A C   
303  O O   . ASP A 44  ? 0.71458 0.79734 0.48045 -0.08596 -0.05370 -0.10085 39  ASP A O   
304  C CB  . ASP A 44  ? 0.72764 0.78265 0.54015 -0.07271 -0.03421 -0.12125 39  ASP A CB  
305  C CG  . ASP A 44  ? 0.74790 0.79447 0.58874 -0.08589 -0.00662 -0.15132 39  ASP A CG  
306  O OD1 . ASP A 44  ? 0.75197 0.75546 0.60999 -0.08894 0.02138  -0.16853 39  ASP A OD1 
307  O OD2 . ASP A 44  ? 0.75948 0.84295 0.60848 -0.09280 -0.01123 -0.15647 39  ASP A OD2 
308  N N   . ARG A 45  ? 0.65525 0.64522 0.42970 -0.03984 -0.06200 -0.06577 40  ARG A N   
309  C CA  . ARG A 45  ? 0.65246 0.65140 0.40396 -0.03952 -0.08149 -0.04033 40  ARG A CA  
310  C C   . ARG A 45  ? 0.64922 0.61606 0.39877 -0.03644 -0.07657 -0.03704 40  ARG A C   
311  O O   . ARG A 45  ? 0.59977 0.58959 0.33746 -0.05439 -0.07405 -0.03994 40  ARG A O   
312  C CB  . ARG A 45  ? 0.64891 0.63619 0.39568 -0.01758 -0.10303 -0.00977 40  ARG A CB  
313  C CG  . ARG A 45  ? 0.65524 0.68342 0.40841 -0.01646 -0.10991 -0.00967 40  ARG A CG  
314  C CD  . ARG A 45  ? 0.66747 0.76752 0.40852 -0.04266 -0.11272 -0.01718 40  ARG A CD  
315  N NE  . ARG A 45  ? 0.72350 0.84272 0.44114 -0.04371 -0.12921 0.01460  40  ARG A NE  
316  C CZ  . ARG A 45  ? 0.79581 0.94102 0.50751 -0.02926 -0.14914 0.04946  40  ARG A CZ  
317  N NH1 . ARG A 45  ? 0.81816 0.97855 0.54695 -0.01224 -0.15627 0.05351  40  ARG A NH1 
318  N NH2 . ARG A 45  ? 0.79781 0.95473 0.48894 -0.03045 -0.16033 0.08293  40  ARG A NH2 
319  N N   . LEU A 46  ? 0.57625 0.49963 0.33698 -0.01549 -0.07505 -0.03166 41  LEU A N   
320  C CA  . LEU A 46  ? 0.60888 0.51302 0.36824 -0.01216 -0.07510 -0.02593 41  LEU A CA  
321  C C   . LEU A 46  ? 0.60682 0.51907 0.38126 -0.01970 -0.05344 -0.04731 41  LEU A C   
322  O O   . LEU A 46  ? 0.61955 0.54804 0.38867 -0.03293 -0.05088 -0.04982 41  LEU A O   
323  C CB  . LEU A 46  ? 0.60233 0.47125 0.36741 0.01129  -0.08188 -0.01531 41  LEU A CB  
324  C CG  . LEU A 46  ? 0.64089 0.49442 0.39653 0.02213  -0.09929 0.00219  41  LEU A CG  
325  C CD1 . LEU A 46  ? 0.67730 0.50237 0.43769 0.04111  -0.10230 0.00407  41  LEU A CD1 
326  C CD2 . LEU A 46  ? 0.67130 0.52793 0.41077 0.01010  -0.11112 0.01946  41  LEU A CD2 
327  N N   . ASN A 47  ? 0.55106 0.45101 0.34716 -0.01068 -0.03521 -0.06166 42  ASN A N   
328  C CA  . ASN A 47  ? 0.57079 0.46811 0.38967 -0.00944 -0.01089 -0.07832 42  ASN A CA  
329  C C   . ASN A 47  ? 0.59012 0.51869 0.40909 -0.03615 0.00470  -0.10442 42  ASN A C   
330  O O   . ASN A 47  ? 0.59934 0.53488 0.43085 -0.03742 0.01884  -0.11439 42  ASN A O   
331  C CB  . ASN A 47  ? 0.59408 0.46333 0.43843 0.00783  0.00841  -0.08220 42  ASN A CB  
332  C CG  . ASN A 47  ? 0.64036 0.48819 0.48600 0.03606  -0.00231 -0.05727 42  ASN A CG  
333  O OD1 . ASN A 47  ? 0.62522 0.47907 0.45762 0.04163  -0.02099 -0.04363 42  ASN A OD1 
334  N ND2 . ASN A 47  ? 0.65175 0.47773 0.51326 0.05116  0.01141  -0.05281 42  ASN A ND2 
335  N N   . PRO A 48  ? 0.58928 0.54538 0.39604 -0.05816 0.00379  -0.11830 43  PRO A N   
336  C CA  . PRO A 48  ? 0.59978 0.59769 0.40082 -0.08717 0.01734  -0.14544 43  PRO A CA  
337  C C   . PRO A 48  ? 0.62587 0.64814 0.40533 -0.09594 0.00477  -0.13107 43  PRO A C   
338  O O   . PRO A 48  ? 0.67962 0.72460 0.46425 -0.11030 0.02244  -0.15220 43  PRO A O   
339  C CB  . PRO A 48  ? 0.59267 0.62898 0.37896 -0.10813 0.01042  -0.15602 43  PRO A CB  
340  C CG  . PRO A 48  ? 0.60938 0.61271 0.41165 -0.09061 0.00986  -0.14976 43  PRO A CG  
341  C CD  . PRO A 48  ? 0.57900 0.53866 0.38176 -0.05913 -0.00465 -0.11619 43  PRO A CD  
342  N N   . LEU A 49  ? 0.59407 0.61008 0.35212 -0.08838 -0.02229 -0.09664 44  LEU A N   
343  C CA  . LEU A 49  ? 0.61286 0.64358 0.35357 -0.09818 -0.03120 -0.08026 44  LEU A CA  
344  C C   . LEU A 49  ? 0.63602 0.65095 0.39868 -0.08776 -0.01913 -0.08629 44  LEU A C   
345  O O   . LEU A 49  ? 0.64672 0.69012 0.40910 -0.10314 -0.00852 -0.09644 44  LEU A O   
346  C CB  . LEU A 49  ? 0.65953 0.67295 0.38014 -0.09046 -0.05766 -0.04282 44  LEU A CB  
347  C CG  . LEU A 49  ? 0.73695 0.76229 0.43986 -0.10580 -0.06356 -0.02400 44  LEU A CG  
348  C CD1 . LEU A 49  ? 0.79807 0.84005 0.47308 -0.11437 -0.08060 0.00709  44  LEU A CD1 
349  C CD2 . LEU A 49  ? 0.72870 0.71577 0.44292 -0.09345 -0.06835 -0.01310 44  LEU A CD2 
350  N N   . PHE A 50  ? 0.64676 0.62487 0.42881 -0.06129 -0.02082 -0.07902 45  PHE A N   
351  C CA  . PHE A 50  ? 0.60532 0.58125 0.41203 -0.04786 -0.00990 -0.08300 45  PHE A CA  
352  C C   . PHE A 50  ? 0.58583 0.57916 0.41725 -0.05196 0.02003  -0.11228 45  PHE A C   
353  O O   . PHE A 50  ? 0.57147 0.58583 0.41869 -0.05195 0.03100  -0.11921 45  PHE A O   
354  C CB  . PHE A 50  ? 0.61094 0.55542 0.43346 -0.01773 -0.01479 -0.07025 45  PHE A CB  
355  C CG  . PHE A 50  ? 0.60903 0.53485 0.41122 -0.01308 -0.04008 -0.04858 45  PHE A CG  
356  C CD1 . PHE A 50  ? 0.61424 0.54608 0.39618 -0.03003 -0.05502 -0.03726 45  PHE A CD1 
357  C CD2 . PHE A 50  ? 0.55858 0.45859 0.36389 0.00766  -0.04549 -0.04034 45  PHE A CD2 
358  C CE1 . PHE A 50  ? 0.62090 0.52758 0.38946 -0.02533 -0.07335 -0.02091 45  PHE A CE1 
359  C CE2 . PHE A 50  ? 0.57417 0.45698 0.36364 0.01219  -0.06515 -0.02594 45  PHE A CE2 
360  C CZ  . PHE A 50  ? 0.60604 0.48927 0.37876 -0.00381 -0.07836 -0.01760 45  PHE A CZ  
361  N N   . ALA A 51  ? 0.59464 0.58093 0.43294 -0.05671 0.03578  -0.13261 46  ALA A N   
362  C CA  . ALA A 51  ? 0.66786 0.66155 0.53437 -0.06165 0.06987  -0.16652 46  ALA A CA  
363  C C   . ALA A 51  ? 0.67950 0.72217 0.53191 -0.09187 0.07796  -0.18803 46  ALA A C   
364  O O   . ALA A 51  ? 0.68938 0.74435 0.56820 -0.09193 0.10497  -0.21259 46  ALA A O   
365  C CB  . ALA A 51  ? 0.69049 0.66404 0.56756 -0.06651 0.08657  -0.18761 46  ALA A CB  
366  N N   . ARG A 52  ? 0.69763 0.77121 0.51004 -0.11604 0.05666  -0.17735 47  ARG A N   
367  C CA  . ARG A 52  ? 0.74108 0.86831 0.53445 -0.14558 0.06287  -0.19108 47  ARG A CA  
368  C C   . ARG A 52  ? 0.69414 0.83074 0.50000 -0.13955 0.06623  -0.18275 47  ARG A C   
369  O O   . ARG A 52  ? 0.67817 0.85563 0.48713 -0.15743 0.08516  -0.20554 47  ARG A O   
370  C CB  . ARG A 52  ? 0.80444 0.96250 0.55211 -0.16678 0.03657  -0.16687 47  ARG A CB  
371  C CG  . ARG A 52  ? 0.86541 1.03222 0.60029 -0.17394 0.02946  -0.17279 47  ARG A CG  
372  C CD  . ARG A 52  ? 0.95807 1.18198 0.65008 -0.19869 0.01071  -0.15468 47  ARG A CD  
373  N NE  . ARG A 52  ? 1.00666 1.21479 0.67716 -0.18950 -0.01611 -0.10390 47  ARG A NE  
374  C CZ  . ARG A 52  ? 1.02948 1.26638 0.67612 -0.20610 -0.02055 -0.08298 47  ARG A CZ  
375  N NH1 . ARG A 52  ? 1.03843 1.32920 0.67681 -0.23229 -0.00167 -0.10876 47  ARG A NH1 
376  N NH2 . ARG A 52  ? 1.02630 1.23695 0.65862 -0.19792 -0.04096 -0.03736 47  ARG A NH2 
377  N N   . TYR A 53  ? 0.69263 0.92249 0.43438 -0.13200 0.02201  -0.12775 48  TYR A N   
378  C CA  . TYR A 53  ? 0.68497 0.89592 0.42376 -0.12682 0.03623  -0.11557 48  TYR A CA  
379  C C   . TYR A 53  ? 0.66426 0.85356 0.45067 -0.11662 0.06388  -0.13504 48  TYR A C   
380  O O   . TYR A 53  ? 0.65687 0.83290 0.45600 -0.10854 0.07257  -0.12458 48  TYR A O   
381  C CB  . TYR A 53  ? 0.66238 0.85032 0.39593 -0.10914 0.01469  -0.07533 48  TYR A CB  
382  C CG  . TYR A 53  ? 0.70541 0.90531 0.39340 -0.11863 -0.01367 -0.04951 48  TYR A CG  
383  C CD1 . TYR A 53  ? 0.74386 0.95594 0.43374 -0.11336 -0.04311 -0.04026 48  TYR A CD1 
384  C CD2 . TYR A 53  ? 0.72248 0.92195 0.36904 -0.13440 -0.01254 -0.03305 48  TYR A CD2 
385  C CE1 . TYR A 53  ? 0.78121 0.99959 0.43368 -0.12018 -0.07618 -0.01082 48  TYR A CE1 
386  C CE2 . TYR A 53  ? 0.78188 0.98368 0.38081 -0.14623 -0.04192 -0.00294 48  TYR A CE2 
387  C CZ  . TYR A 53  ? 0.81878 1.02754 0.42111 -0.13746 -0.07638 0.01022  48  TYR A CZ  
388  O OH  . TYR A 53  ? 0.89719 1.10354 0.45640 -0.14719 -0.11248 0.04600  48  TYR A OH  
389  N N   . GLY A 54  ? 0.67171 0.85639 0.48774 -0.11782 0.07523  -0.16147 49  GLY A N   
390  C CA  . GLY A 54  ? 0.68414 0.83872 0.54866 -0.10668 0.09537  -0.17369 49  GLY A CA  
391  C C   . GLY A 54  ? 0.67238 0.79050 0.55593 -0.08680 0.08461  -0.14297 49  GLY A C   
392  O O   . GLY A 54  ? 0.69774 0.78855 0.61557 -0.07625 0.09303  -0.14015 49  GLY A O   
393  N N   . LEU A 55  ? 0.66241 0.77997 0.52643 -0.08248 0.06552  -0.12093 50  LEU A N   
394  C CA  . LEU A 55  ? 0.64743 0.73357 0.51804 -0.06973 0.05813  -0.09530 50  LEU A CA  
395  C C   . LEU A 55  ? 0.69429 0.76738 0.57931 -0.07407 0.06242  -0.10309 50  LEU A C   
396  O O   . LEU A 55  ? 0.68681 0.78487 0.56989 -0.08058 0.05762  -0.11440 50  LEU A O   
397  C CB  . LEU A 55  ? 0.62118 0.71244 0.46550 -0.06333 0.03985  -0.07073 50  LEU A CB  
398  C CG  . LEU A 55  ? 0.63579 0.72551 0.46627 -0.06092 0.03655  -0.05433 50  LEU A CG  
399  C CD1 . LEU A 55  ? 0.65581 0.74534 0.45998 -0.05759 0.01798  -0.03241 50  LEU A CD1 
400  C CD2 . LEU A 55  ? 0.61355 0.67583 0.46416 -0.05355 0.04072  -0.04319 50  LEU A CD2 
401  N N   . GLN A 56  ? 0.76083 0.79623 0.66123 -0.07260 0.06963  -0.09518 51  GLN A N   
402  C CA  . GLN A 56  ? 0.84424 0.86131 0.75175 -0.08305 0.07703  -0.09928 51  GLN A CA  
403  C C   . GLN A 56  ? 0.84032 0.86087 0.72953 -0.08305 0.07093  -0.08537 51  GLN A C   
404  O O   . GLN A 56  ? 0.77019 0.79714 0.64321 -0.07262 0.05950  -0.07031 51  GLN A O   
405  C CB  . GLN A 56  ? 0.90820 0.87666 0.83119 -0.08447 0.08291  -0.08855 51  GLN A CB  
406  C CG  . GLN A 56  ? 0.96729 0.92746 0.92457 -0.08650 0.09536  -0.11333 51  GLN A CG  
407  C CD  . GLN A 56  ? 1.02452 0.93047 1.00822 -0.08207 0.09493  -0.09732 51  GLN A CD  
408  O OE1 . GLN A 56  ? 1.05273 0.92102 1.02248 -0.09102 0.09046  -0.07389 51  GLN A OE1 
409  N NE2 . GLN A 56  ? 1.03048 0.93254 1.05416 -0.06950 0.09920  -0.10979 51  GLN A NE2 
410  N N   . PRO A 57  ? 0.95457 0.97238 0.84951 -0.09685 0.08146  -0.09437 52  PRO A N   
411  C CA  . PRO A 57  ? 0.95746 0.97941 0.84139 -0.09913 0.08309  -0.08835 52  PRO A CA  
412  C C   . PRO A 57  ? 0.94567 0.93085 0.79936 -0.09741 0.07909  -0.06156 52  PRO A C   
413  O O   . PRO A 57  ? 0.94539 0.89190 0.78697 -0.10658 0.08091  -0.04594 52  PRO A O   
414  C CB  . PRO A 57  ? 1.00190 1.02312 0.89848 -0.12152 0.10205  -0.10479 52  PRO A CB  
415  C CG  . PRO A 57  ? 1.00061 1.03853 0.92184 -0.12672 0.10383  -0.12645 52  PRO A CG  
416  C CD  . PRO A 57  ? 0.98293 1.00280 0.89906 -0.11380 0.09514  -0.11778 52  PRO A CD  
417  N N   . GLY A 58  ? 0.80556 0.80110 0.64793 -0.08653 0.07048  -0.05514 53  GLY A N   
418  C CA  . GLY A 58  ? 0.74509 0.71155 0.55616 -0.08843 0.06560  -0.03422 53  GLY A CA  
419  C C   . GLY A 58  ? 0.68334 0.64146 0.48913 -0.07611 0.04873  -0.01556 53  GLY A C   
420  O O   . GLY A 58  ? 0.63834 0.58132 0.42101 -0.07697 0.04067  -0.00035 53  GLY A O   
421  N N   . GLU A 59  ? 0.67319 0.64391 0.50115 -0.06785 0.04557  -0.02015 54  GLU A N   
422  C CA  . GLU A 59  ? 0.60944 0.58132 0.44061 -0.05830 0.03461  -0.00783 54  GLU A CA  
423  C C   . GLU A 59  ? 0.54590 0.53757 0.36541 -0.05147 0.02646  -0.00573 54  GLU A C   
424  O O   . GLU A 59  ? 0.54558 0.53207 0.35680 -0.04943 0.01774  0.00881  54  GLU A O   
425  C CB  . GLU A 59  ? 0.59140 0.57296 0.45301 -0.05470 0.04057  -0.02087 54  GLU A CB  
426  C CG  . GLU A 59  ? 0.61637 0.56576 0.49740 -0.05850 0.04444  -0.01719 54  GLU A CG  
427  C CD  . GLU A 59  ? 0.68248 0.63832 0.60345 -0.05376 0.05448  -0.03803 54  GLU A CD  
428  O OE1 . GLU A 59  ? 0.68070 0.67090 0.60416 -0.05405 0.06249  -0.06071 54  GLU A OE1 
429  O OE2 . GLU A 59  ? 0.71411 0.63856 0.66347 -0.05126 0.05386  -0.03210 54  GLU A OE2 
430  N N   . PHE A 60  ? 0.53946 0.55277 0.36112 -0.04904 0.02655  -0.01816 55  PHE A N   
431  C CA  . PHE A 60  ? 0.53805 0.56001 0.34894 -0.04240 0.01438  -0.01058 55  PHE A CA  
432  C C   . PHE A 60  ? 0.54701 0.54317 0.34272 -0.04216 0.01151  0.00071  55  PHE A C   
433  O O   . PHE A 60  ? 0.55943 0.54726 0.34215 -0.04096 0.00228  0.01407  55  PHE A O   
434  C CB  . PHE A 60  ? 0.53801 0.58490 0.36284 -0.03793 0.00918  -0.02290 55  PHE A CB  
435  C CG  . PHE A 60  ? 0.56551 0.61451 0.38495 -0.02889 -0.00900 -0.01048 55  PHE A CG  
436  C CD1 . PHE A 60  ? 0.59593 0.65925 0.39884 -0.03153 -0.02272 -0.00004 55  PHE A CD1 
437  C CD2 . PHE A 60  ? 0.55548 0.58966 0.38620 -0.02005 -0.01149 -0.01025 55  PHE A CD2 
438  C CE1 . PHE A 60  ? 0.58043 0.63713 0.37504 -0.02526 -0.04356 0.01809  55  PHE A CE1 
439  C CE2 . PHE A 60  ? 0.57307 0.60051 0.40678 -0.00939 -0.03047 0.00268  55  PHE A CE2 
440  C CZ  . PHE A 60  ? 0.58709 0.62299 0.40140 -0.01179 -0.04915 0.02065  55  PHE A CZ  
441  N N   . ASP A 61  ? 0.55640 0.53955 0.35032 -0.04800 0.02183  -0.00697 56  ASP A N   
442  C CA  . ASP A 61  ? 0.57455 0.53441 0.34886 -0.05308 0.02335  -0.00376 56  ASP A CA  
443  C C   . ASP A 61  ? 0.58222 0.52368 0.33368 -0.06001 0.01369  0.01570  56  ASP A C   
444  O O   . ASP A 61  ? 0.60089 0.52981 0.33895 -0.06131 0.00724  0.02115  56  ASP A O   
445  C CB  . ASP A 61  ? 0.59322 0.54537 0.36083 -0.06678 0.04142  -0.01777 56  ASP A CB  
446  C CG  . ASP A 61  ? 0.62978 0.56583 0.38129 -0.07376 0.05002  -0.02786 56  ASP A CG  
447  O OD1 . ASP A 61  ? 0.63521 0.56354 0.38887 -0.06410 0.04043  -0.02512 56  ASP A OD1 
448  O OD2 . ASP A 61  ? 0.68076 0.60989 0.41572 -0.09218 0.06873  -0.04051 56  ASP A OD2 
449  N N   . VAL A 62  ? 0.64903 0.58908 0.40298 -0.06417 0.01109  0.02552  57  VAL A N   
450  C CA  . VAL A 62  ? 0.58825 0.51952 0.33478 -0.06876 -0.00229 0.04411  57  VAL A CA  
451  C C   . VAL A 62  ? 0.57953 0.52642 0.33569 -0.06227 -0.00922 0.04806  57  VAL A C   
452  O O   . VAL A 62  ? 0.60584 0.54457 0.34838 -0.06919 -0.01805 0.05740  57  VAL A O   
453  C CB  . VAL A 62  ? 0.59203 0.52065 0.35799 -0.06836 -0.00642 0.05332  57  VAL A CB  
454  C CG1 . VAL A 62  ? 0.59888 0.52828 0.37402 -0.06924 -0.02467 0.07210  57  VAL A CG1 
455  C CG2 . VAL A 62  ? 0.62111 0.52515 0.36719 -0.08154 -0.00122 0.05618  57  VAL A CG2 
456  N N   . LEU A 63  ? 0.56565 0.53519 0.34053 -0.05393 -0.00453 0.04033  58  LEU A N   
457  C CA  . LEU A 63  ? 0.57208 0.55638 0.34694 -0.05460 -0.00833 0.04541  58  LEU A CA  
458  C C   . LEU A 63  ? 0.59423 0.56196 0.34764 -0.05564 -0.01479 0.05083  58  LEU A C   
459  O O   . LEU A 63  ? 0.63676 0.59727 0.38000 -0.06328 -0.02083 0.06174  58  LEU A O   
460  C CB  . LEU A 63  ? 0.54535 0.55717 0.33239 -0.05210 -0.00057 0.03398  58  LEU A CB  
461  C CG  . LEU A 63  ? 0.53735 0.56344 0.35504 -0.05003 0.00978  0.02165  58  LEU A CG  
462  C CD1 . LEU A 63  ? 0.57169 0.62775 0.39281 -0.05445 0.02072  0.00513  58  LEU A CD1 
463  C CD2 . LEU A 63  ? 0.53771 0.56356 0.37959 -0.05005 0.00582  0.03075  58  LEU A CD2 
464  N N   . ALA A 64  ? 0.57151 0.53270 0.32507 -0.04806 -0.01344 0.04190  59  ALA A N   
465  C CA  . ALA A 64  ? 0.63487 0.57603 0.38213 -0.04414 -0.02054 0.04490  59  ALA A CA  
466  C C   . ALA A 64  ? 0.67441 0.58653 0.40653 -0.05330 -0.01933 0.04532  59  ALA A C   
467  O O   . ALA A 64  ? 0.68825 0.57904 0.41186 -0.05669 -0.02620 0.05280  59  ALA A O   
468  C CB  . ALA A 64  ? 0.59157 0.53876 0.35935 -0.03141 -0.01889 0.03055  59  ALA A CB  
469  N N   . THR A 65  ? 0.63435 0.54245 0.35816 -0.06136 -0.01154 0.03805  60  THR A N   
470  C CA  . THR A 65  ? 0.66385 0.54731 0.36328 -0.07646 -0.01140 0.03643  60  THR A CA  
471  C C   . THR A 65  ? 0.68877 0.57244 0.38001 -0.08745 -0.02428 0.05322  60  THR A C   
472  O O   . THR A 65  ? 0.70815 0.57062 0.38531 -0.09791 -0.02786 0.05291  60  THR A O   
473  C CB  . THR A 65  ? 0.67489 0.55520 0.35590 -0.08901 -0.00351 0.03043  60  THR A CB  
474  O OG1 . THR A 65  ? 0.65571 0.54015 0.34816 -0.08307 0.01311  0.01086  60  THR A OG1 
475  C CG2 . THR A 65  ? 0.71483 0.57213 0.35913 -0.11117 -0.00471 0.02756  60  THR A CG2 
476  N N   . LEU A 66  ? 0.64600 0.55520 0.35286 -0.08592 -0.02963 0.06452  61  LEU A N   
477  C CA  . LEU A 66  ? 0.65703 0.57805 0.37032 -0.09613 -0.03968 0.07693  61  LEU A CA  
478  C C   . LEU A 66  ? 0.71117 0.62771 0.42209 -0.09908 -0.03920 0.08119  61  LEU A C   
479  O O   . LEU A 66  ? 0.73242 0.64020 0.43540 -0.11464 -0.04515 0.08703  61  LEU A O   
480  C CB  . LEU A 66  ? 0.59816 0.55164 0.34447 -0.08989 -0.04103 0.08165  61  LEU A CB  
481  C CG  . LEU A 66  ? 0.63622 0.58806 0.38895 -0.09002 -0.04973 0.08733  61  LEU A CG  
482  C CD1 . LEU A 66  ? 0.62760 0.60637 0.42753 -0.07779 -0.04863 0.08765  61  LEU A CD1 
483  C CD2 . LEU A 66  ? 0.66996 0.61522 0.40749 -0.10742 -0.06825 0.09897  61  LEU A CD2 
484  N N   . ARG A 67  ? 0.69578 0.61726 0.41066 -0.08782 -0.03434 0.08040  62  ARG A N   
485  C CA  . ARG A 67  ? 0.72550 0.63859 0.43018 -0.09412 -0.03757 0.09162  62  ARG A CA  
486  C C   . ARG A 67  ? 0.77552 0.64380 0.46584 -0.09771 -0.04338 0.09334  62  ARG A C   
487  O O   . ARG A 67  ? 0.78271 0.63447 0.46241 -0.11445 -0.04718 0.10316  62  ARG A O   
488  C CB  . ARG A 67  ? 0.70178 0.62836 0.40650 -0.08359 -0.03715 0.09304  62  ARG A CB  
489  C CG  . ARG A 67  ? 0.77643 0.68781 0.46012 -0.09282 -0.04567 0.11160  62  ARG A CG  
490  C CD  . ARG A 67  ? 0.79458 0.72431 0.46850 -0.11686 -0.03875 0.12040  62  ARG A CD  
491  N NE  . ARG A 67  ? 0.85709 0.76478 0.50008 -0.13272 -0.04672 0.14283  62  ARG A NE  
492  C CZ  . ARG A 67  ? 0.86247 0.72410 0.49379 -0.14074 -0.05627 0.15710  62  ARG A CZ  
493  N NH1 . ARG A 67  ? 0.83872 0.67686 0.48526 -0.13552 -0.05653 0.14577  62  ARG A NH1 
494  N NH2 . ARG A 67  ? 0.86181 0.69742 0.46255 -0.15707 -0.06571 0.18264  62  ARG A NH2 
495  N N   . ARG A 68  ? 0.73745 0.58566 0.43238 -0.08361 -0.04154 0.08036  63  ARG A N   
496  C CA  . ARG A 68  ? 0.78547 0.58878 0.47778 -0.08393 -0.04405 0.07611  63  ARG A CA  
497  C C   . ARG A 68  ? 0.77373 0.55798 0.44970 -0.10363 -0.03979 0.06492  63  ARG A C   
498  O O   . ARG A 68  ? 0.82981 0.57314 0.50384 -0.10737 -0.03820 0.05505  63  ARG A O   
499  C CB  . ARG A 68  ? 0.80209 0.59588 0.51771 -0.06182 -0.04037 0.05954  63  ARG A CB  
500  C CG  . ARG A 68  ? 0.75223 0.56330 0.47038 -0.06085 -0.02499 0.03620  63  ARG A CG  
501  C CD  . ARG A 68  ? 0.75982 0.56782 0.51112 -0.04135 -0.01749 0.01529  63  ARG A CD  
502  N NE  . ARG A 68  ? 0.73564 0.57521 0.49251 -0.04018 -0.00396 0.00032  63  ARG A NE  
503  C CZ  . ARG A 68  ? 0.79079 0.62930 0.52725 -0.05639 0.01339  -0.01720 63  ARG A CZ  
504  N NH1 . ARG A 68  ? 0.72844 0.54007 0.43596 -0.07532 0.01854  -0.02492 63  ARG A NH1 
505  N NH2 . ARG A 68  ? 0.77313 0.63619 0.51308 -0.05804 0.02505  -0.02640 63  ARG A NH2 
506  N N   . SER A 69  ? 0.72516 0.53648 0.39165 -0.11704 -0.04017 0.06598  64  SER A N   
507  C CA  . SER A 69  ? 0.83514 0.63329 0.48152 -0.14117 -0.04324 0.06000  64  SER A CA  
508  C C   . SER A 69  ? 0.86405 0.65500 0.50941 -0.15958 -0.05092 0.07303  64  SER A C   
509  O O   . SER A 69  ? 0.89010 0.65934 0.51957 -0.18161 -0.05350 0.06491  64  SER A O   
510  C CB  . SER A 69  ? 0.83137 0.66082 0.47112 -0.14961 -0.04914 0.06266  64  SER A CB  
511  O OG  . SER A 69  ? 0.83333 0.70039 0.49671 -0.14902 -0.05788 0.07983  64  SER A OG  
512  N N   . GLY A 70  ? 0.78380 0.82879 0.47675 -0.16877 -0.05201 0.05452  65  GLY A N   
513  C CA  . GLY A 70  ? 0.77756 0.83556 0.46281 -0.19904 -0.05649 0.06051  65  GLY A CA  
514  C C   . GLY A 70  ? 0.74003 0.88009 0.44444 -0.20261 -0.05868 0.07646  65  GLY A C   
515  O O   . GLY A 70  ? 0.69157 0.87752 0.41069 -0.18589 -0.05895 0.08228  65  GLY A O   
516  N N   . ALA A 71  ? 0.74856 0.90808 0.45349 -0.22385 -0.05978 0.08506  66  ALA A N   
517  C CA  . ALA A 71  ? 0.73536 0.97989 0.46316 -0.22697 -0.06015 0.10001  66  ALA A CA  
518  C C   . ALA A 71  ? 0.75018 1.04946 0.47866 -0.24369 -0.06836 0.09991  66  ALA A C   
519  O O   . ALA A 71  ? 0.81424 1.08546 0.51599 -0.27332 -0.07392 0.08660  66  ALA A O   
520  C CB  . ALA A 71  ? 0.76454 1.02192 0.48803 -0.25639 -0.05940 0.10691  66  ALA A CB  
521  N N   . PRO A 72  ? 0.72788 1.10473 0.48502 -0.22510 -0.06935 0.11468  67  PRO A N   
522  C CA  . PRO A 72  ? 0.71259 1.12459 0.50109 -0.18937 -0.06035 0.12874  67  PRO A CA  
523  C C   . PRO A 72  ? 0.70339 1.07738 0.49726 -0.14658 -0.05357 0.12788  67  PRO A C   
524  O O   . PRO A 72  ? 0.69212 1.10026 0.51069 -0.11518 -0.04675 0.13952  67  PRO A O   
525  C CB  . PRO A 72  ? 0.68934 1.20181 0.50522 -0.19065 -0.06592 0.14484  67  PRO A CB  
526  C CG  . PRO A 72  ? 0.72304 1.24190 0.52181 -0.20801 -0.07855 0.14052  67  PRO A CG  
527  C CD  . PRO A 72  ? 0.74916 1.18856 0.50823 -0.24054 -0.08016 0.11908  67  PRO A CD  
528  N N   . TYR A 73  ? 0.71392 1.01850 0.48516 -0.14604 -0.05422 0.11377  68  TYR A N   
529  C CA  . TYR A 73  ? 0.71763 0.98244 0.49117 -0.11197 -0.04743 0.11120  68  TYR A CA  
530  C C   . TYR A 73  ? 0.72531 1.03242 0.51362 -0.08845 -0.04803 0.12352  68  TYR A C   
531  O O   . TYR A 73  ? 0.74872 1.05557 0.55181 -0.05682 -0.03973 0.13138  68  TYR A O   
532  C CB  . TYR A 73  ? 0.69545 0.93559 0.47691 -0.09333 -0.03753 0.11259  68  TYR A CB  
533  C CG  . TYR A 73  ? 0.71638 0.93151 0.48545 -0.11751 -0.03844 0.10847  68  TYR A CG  
534  C CD1 . TYR A 73  ? 0.73666 0.88702 0.48447 -0.12924 -0.04200 0.09687  68  TYR A CD1 
535  C CD2 . TYR A 73  ? 0.72038 0.97715 0.49909 -0.12780 -0.03505 0.11750  68  TYR A CD2 
536  C CE1 . TYR A 73  ? 0.75560 0.87740 0.48957 -0.15040 -0.04394 0.09697  68  TYR A CE1 
537  C CE2 . TYR A 73  ? 0.74355 0.97543 0.50657 -0.15289 -0.03607 0.11644  68  TYR A CE2 
538  C CZ  . TYR A 73  ? 0.77723 0.93864 0.51663 -0.16401 -0.04141 0.10746  68  TYR A CZ  
539  O OH  . TYR A 73  ? 0.84109 0.97263 0.56264 -0.18799 -0.04342 0.11015  68  TYR A OH  
540  N N   . ALA A 74  ? 0.66673 1.00726 0.44760 -0.10551 -0.05814 0.12561  69  ALA A N   
541  C CA  . ALA A 74  ? 0.67934 1.06548 0.47151 -0.08656 -0.06224 0.14184  69  ALA A CA  
542  C C   . ALA A 74  ? 0.68121 1.05066 0.44662 -0.10205 -0.06912 0.13330  69  ALA A C   
543  O O   . ALA A 74  ? 0.66195 1.03531 0.40748 -0.13730 -0.07651 0.12172  69  ALA A O   
544  C CB  . ALA A 74  ? 0.69618 1.17087 0.51226 -0.09197 -0.06986 0.16022  69  ALA A CB  
545  N N   . LEU A 75  ? 0.68272 1.03209 0.44454 -0.07819 -0.06538 0.13812  70  LEU A N   
546  C CA  . LEU A 75  ? 0.67641 1.00983 0.41102 -0.09100 -0.06889 0.12995  70  LEU A CA  
547  C C   . LEU A 75  ? 0.68203 1.04983 0.42040 -0.07061 -0.07331 0.15314  70  LEU A C   
548  O O   . LEU A 75  ? 0.67783 1.04966 0.43749 -0.03777 -0.06814 0.17050  70  LEU A O   
549  C CB  . LEU A 75  ? 0.66384 0.92307 0.38344 -0.08634 -0.05743 0.10903  70  LEU A CB  
550  C CG  . LEU A 75  ? 0.66020 0.87120 0.37279 -0.10154 -0.05287 0.08674  70  LEU A CG  
551  C CD1 . LEU A 75  ? 0.64152 0.79399 0.34918 -0.08712 -0.04209 0.07249  70  LEU A CD1 
552  C CD2 . LEU A 75  ? 0.69042 0.90465 0.37922 -0.13854 -0.05936 0.07176  70  LEU A CD2 
553  N N   . THR A 76  ? 0.68477 1.07313 0.39885 -0.09085 -0.08228 0.15329  71  THR A N   
554  C CA  . THR A 76  ? 0.72615 1.13363 0.43515 -0.07343 -0.08630 0.17546  71  THR A CA  
555  C C   . THR A 76  ? 0.73503 1.07649 0.43640 -0.05264 -0.07148 0.16920  71  THR A C   
556  O O   . THR A 76  ? 0.68993 0.97940 0.38310 -0.06017 -0.06097 0.14392  71  THR A O   
557  C CB  . THR A 76  ? 0.75524 1.19533 0.43223 -0.10488 -0.09846 0.17432  71  THR A CB  
558  O OG1 . THR A 76  ? 0.77400 1.15845 0.41929 -0.12470 -0.08845 0.14448  71  THR A OG1 
559  C CG2 . THR A 76  ? 0.75350 1.24746 0.44039 -0.13387 -0.11048 0.17101  71  THR A CG2 
560  N N   . PRO A 77  ? 0.79993 1.14222 0.50422 -0.02669 -0.07048 0.19294  72  PRO A N   
561  C CA  . PRO A 77  ? 0.79159 1.07203 0.48513 -0.01335 -0.05619 0.18656  72  PRO A CA  
562  C C   . PRO A 77  ? 0.75408 1.00961 0.41580 -0.03930 -0.05197 0.16470  72  PRO A C   
563  O O   . PRO A 77  ? 0.77414 0.98071 0.43142 -0.03596 -0.03856 0.14894  72  PRO A O   
564  C CB  . PRO A 77  ? 0.82489 1.11508 0.52094 0.01358  -0.05851 0.21991  72  PRO A CB  
565  C CG  . PRO A 77  ? 0.82831 1.18181 0.55114 0.02673  -0.07071 0.24266  72  PRO A CG  
566  C CD  . PRO A 77  ? 0.81280 1.21060 0.53070 -0.00794 -0.08213 0.22786  72  PRO A CD  
567  N N   . THR A 78  ? 0.73342 1.02486 0.37306 -0.06646 -0.06229 0.16170  73  THR A N   
568  C CA  . THR A 78  ? 0.79366 1.06292 0.40101 -0.09182 -0.05545 0.13716  73  THR A CA  
569  C C   . THR A 78  ? 0.78866 1.02385 0.39879 -0.10531 -0.04705 0.10282  73  THR A C   
570  O O   . THR A 78  ? 0.78809 0.98126 0.39130 -0.10587 -0.03310 0.08128  73  THR A O   
571  C CB  . THR A 78  ? 0.82370 1.14130 0.40177 -0.11862 -0.06860 0.14389  73  THR A CB  
572  O OG1 . THR A 78  ? 0.86034 1.19764 0.44602 -0.10032 -0.07541 0.17550  73  THR A OG1 
573  C CG2 . THR A 78  ? 0.83516 1.12845 0.37736 -0.14548 -0.05799 0.11436  73  THR A CG2 
574  N N   . ALA A 79  ? 0.77674 1.03098 0.39740 -0.11641 -0.05537 0.09872  74  ALA A N   
575  C CA  . ALA A 79  ? 0.78533 0.99948 0.41023 -0.12515 -0.04810 0.07151  74  ALA A CA  
576  C C   . ALA A 79  ? 0.77085 0.94239 0.41982 -0.09770 -0.03715 0.06962  74  ALA A C   
577  O O   . ALA A 79  ? 0.77816 0.90667 0.42635 -0.09855 -0.02739 0.04727  74  ALA A O   
578  C CB  . ALA A 79  ? 0.77800 1.02064 0.41099 -0.14178 -0.05916 0.07342  74  ALA A CB  
579  N N   . LEU A 80  ? 0.73197 0.91562 0.40200 -0.07279 -0.03846 0.09291  75  LEU A N   
580  C CA  . LEU A 80  ? 0.72145 0.86697 0.40982 -0.05023 -0.02844 0.09111  75  LEU A CA  
581  C C   . LEU A 80  ? 0.72249 0.83418 0.40021 -0.04751 -0.01694 0.07930  75  LEU A C   
582  O O   . LEU A 80  ? 0.71873 0.79671 0.40593 -0.04206 -0.00900 0.06435  75  LEU A O   
583  C CB  . LEU A 80  ? 0.71834 0.88085 0.42517 -0.02551 -0.02971 0.11651  75  LEU A CB  
584  C CG  . LEU A 80  ? 0.71790 0.84551 0.44097 -0.00416 -0.01980 0.11607  75  LEU A CG  
585  C CD1 . LEU A 80  ? 0.64676 0.75780 0.38025 -0.01015 -0.01900 0.10049  75  LEU A CD1 
586  C CD2 . LEU A 80  ? 0.73024 0.87606 0.46757 0.01980  -0.01948 0.13984  75  LEU A CD2 
587  N N   . TYR A 81  ? 0.78147 0.90629 0.43935 -0.05292 -0.01632 0.08671  76  TYR A N   
588  C CA  . TYR A 81  ? 0.74630 0.84529 0.39361 -0.05394 -0.00371 0.07523  76  TYR A CA  
589  C C   . TYR A 81  ? 0.72644 0.81100 0.36489 -0.07034 0.00337  0.04453  76  TYR A C   
590  O O   . TYR A 81  ? 0.72084 0.78004 0.36824 -0.06474 0.01481  0.02889  76  TYR A O   
591  C CB  . TYR A 81  ? 0.74295 0.85891 0.36709 -0.05795 -0.00419 0.09307  76  TYR A CB  
592  C CG  . TYR A 81  ? 0.77713 0.87283 0.38775 -0.06523 0.01040  0.07901  76  TYR A CG  
593  C CD1 . TYR A 81  ? 0.79011 0.85923 0.41077 -0.05268 0.02010  0.08352  76  TYR A CD1 
594  C CD2 . TYR A 81  ? 0.79455 0.89916 0.38198 -0.08680 0.01610  0.05887  76  TYR A CD2 
595  C CE1 . TYR A 81  ? 0.78921 0.84778 0.40044 -0.06204 0.03407  0.07067  76  TYR A CE1 
596  C CE2 . TYR A 81  ? 0.78608 0.87909 0.36419 -0.09319 0.03191  0.04469  76  TYR A CE2 
597  C CZ  . TYR A 81  ? 0.78317 0.85644 0.37500 -0.08104 0.04035  0.05172  76  TYR A CZ  
598  O OH  . TYR A 81  ? 0.83515 0.90491 0.42019 -0.09005 0.05650  0.03805  76  TYR A OH  
599  N N   . ASP A 82  ? 0.73896 0.84009 0.35976 -0.09077 -0.00262 0.03508  77  ASP A N   
600  C CA  . ASP A 82  ? 0.74284 0.82271 0.35128 -0.10542 0.00672  0.00367  77  ASP A CA  
601  C C   . ASP A 82  ? 0.72231 0.76732 0.35395 -0.09515 0.00952  -0.01074 77  ASP A C   
602  O O   . ASP A 82  ? 0.73788 0.75584 0.37176 -0.09298 0.02134  -0.03378 77  ASP A O   
603  C CB  . ASP A 82  ? 0.75726 0.85847 0.33598 -0.13370 -0.00034 -0.00413 77  ASP A CB  
604  C CG  . ASP A 82  ? 0.77206 0.90652 0.32151 -0.14719 -0.00198 0.00639  77  ASP A CG  
605  O OD1 . ASP A 82  ? 0.75297 0.88068 0.29808 -0.14005 0.00925  0.00681  77  ASP A OD1 
606  O OD2 . ASP A 82  ? 0.78060 0.95090 0.31075 -0.16672 -0.01519 0.01575  77  ASP A OD2 
607  N N   . ALA A 83  ? 0.67685 0.72385 0.32611 -0.08778 -0.00067 0.00340  78  ALA A N   
608  C CA  . ALA A 83  ? 0.68524 0.70006 0.35230 -0.08028 -0.00023 -0.00588 78  ALA A CA  
609  C C   . ALA A 83  ? 0.66926 0.67021 0.36142 -0.05697 0.00377  0.00099  78  ALA A C   
610  O O   . ALA A 83  ? 0.69012 0.66655 0.39703 -0.04941 0.00308  -0.00426 78  ALA A O   
611  C CB  . ALA A 83  ? 0.67824 0.70408 0.34717 -0.09016 -0.01239 0.00422  78  ALA A CB  
612  N N   . ALA A 84  ? 0.65261 0.66696 0.34704 -0.04765 0.00735  0.01333  79  ALA A N   
613  C CA  . ALA A 84  ? 0.65463 0.65545 0.36827 -0.03097 0.01172  0.01769  79  ALA A CA  
614  C C   . ALA A 84  ? 0.65330 0.63536 0.37808 -0.02705 0.02012  -0.00214 79  ALA A C   
615  O O   . ALA A 84  ? 0.62861 0.60966 0.34408 -0.03433 0.02778  -0.01900 79  ALA A O   
616  C CB  . ALA A 84  ? 0.69330 0.70445 0.40083 -0.02624 0.01605  0.03253  79  ALA A CB  
617  N N   . MET A 85  ? 0.62016 0.59033 0.36553 -0.01500 0.01890  -0.00029 80  MET A N   
618  C CA  . MET A 85  ? 0.63378 0.59568 0.39653 -0.00754 0.02539  -0.01511 80  MET A CA  
619  C C   . MET A 85  ? 0.60473 0.58219 0.36776 -0.00929 0.03737  -0.01969 80  MET A C   
620  O O   . MET A 85  ? 0.59416 0.57601 0.36501 -0.00781 0.04723  -0.03665 80  MET A O   
621  C CB  . MET A 85  ? 0.64187 0.59478 0.42483 0.00321  0.01827  -0.00860 80  MET A CB  
622  C CG  . MET A 85  ? 0.66958 0.62571 0.47618 0.01305  0.02277  -0.01889 80  MET A CG  
623  S SD  . MET A 85  ? 0.69148 0.62850 0.50815 0.02199  0.02486  -0.03642 80  MET A SD  
624  C CE  . MET A 85  ? 0.68390 0.59476 0.50145 0.02528  0.00829  -0.02284 80  MET A CE  
625  N N   . ILE A 86  ? 0.59499 0.57948 0.34927 -0.01235 0.03809  -0.00481 81  ILE A N   
626  C CA  . ILE A 86  ? 0.61949 0.61462 0.37055 -0.01795 0.04917  -0.00537 81  ILE A CA  
627  C C   . ILE A 86  ? 0.62238 0.62217 0.34526 -0.02718 0.05051  0.00821  81  ILE A C   
628  O O   . ILE A 86  ? 0.64039 0.63459 0.35518 -0.02329 0.04244  0.02564  81  ILE A O   
629  C CB  . ILE A 86  ? 0.63978 0.63052 0.40461 -0.01466 0.04901  0.00136  81  ILE A CB  
630  C CG1 . ILE A 86  ? 0.67566 0.66625 0.46743 -0.00493 0.04292  -0.00679 81  ILE A CG1 
631  C CG2 . ILE A 86  ? 0.65862 0.66108 0.42092 -0.02511 0.06136  -0.00137 81  ILE A CG2 
632  C CD1 . ILE A 86  ? 0.68920 0.68034 0.49198 -0.00585 0.04089  -0.00160 81  ILE A CD1 
633  N N   . SER A 87  ? 0.62636 0.63911 0.33478 -0.03848 0.06099  0.00144  82  SER A N   
634  C CA  . SER A 87  ? 0.65271 0.67194 0.33106 -0.04835 0.06047  0.01711  82  SER A CA  
635  C C   . SER A 87  ? 0.69265 0.70060 0.36253 -0.04939 0.06398  0.03642  82  SER A C   
636  O O   . SER A 87  ? 0.72166 0.73492 0.36985 -0.06202 0.07182  0.04260  82  SER A O   
637  C CB  . SER A 87  ? 0.68450 0.72167 0.34331 -0.06365 0.07052  0.00233  82  SER A CB  
638  O OG  . SER A 87  ? 0.67845 0.72375 0.34468 -0.06915 0.08606  -0.01015 82  SER A OG  
639  N N   . SER A 88  ? 0.73812 0.72682 0.42100 -0.03812 0.05930  0.04570  83  SER A N   
640  C CA  . SER A 88  ? 0.78796 0.75474 0.45832 -0.03888 0.06340  0.06342  83  SER A CA  
641  C C   . SER A 88  ? 0.82500 0.78653 0.47453 -0.03216 0.05673  0.08850  83  SER A C   
642  O O   . SER A 88  ? 0.80832 0.78795 0.45880 -0.02613 0.04662  0.09247  83  SER A O   
643  C CB  . SER A 88  ? 0.79630 0.74193 0.48358 -0.03069 0.06241  0.06166  83  SER A CB  
644  O OG  . SER A 88  ? 0.74750 0.69390 0.44795 -0.01656 0.05210  0.06200  83  SER A OG  
645  N N   . GLY A 89  ? 0.85240 0.78965 0.48308 -0.03387 0.06222  0.10673  84  GLY A N   
646  C CA  . GLY A 89  ? 0.85502 0.78605 0.46648 -0.02439 0.05624  0.13486  84  GLY A CA  
647  C C   . GLY A 89  ? 0.86483 0.77097 0.48623 -0.00128 0.05300  0.14836  84  GLY A C   
648  O O   . GLY A 89  ? 0.80543 0.70759 0.44800 0.00650  0.05247  0.13470  84  GLY A O   
649  N N   . SER A 90  ? 0.90327 0.79268 0.50805 0.01078  0.05142  0.17651  85  SER A N   
650  C CA  . SER A 90  ? 0.90793 0.76970 0.52039 0.03691  0.05200  0.19111  85  SER A CA  
651  C C   . SER A 90  ? 0.85472 0.75087 0.49467 0.05297  0.04263  0.18603  85  SER A C   
652  O O   . SER A 90  ? 0.90028 0.77886 0.55418 0.06882  0.04694  0.18222  85  SER A O   
653  C CB  . SER A 90  ? 0.92511 0.73459 0.53434 0.03424  0.06582  0.17992  85  SER A CB  
654  O OG  . SER A 90  ? 0.99411 0.75549 0.57587 0.03387  0.07437  0.19950  85  SER A OG  
655  N N   . MET A 91  ? 0.83663 0.78193 0.48128 0.04596  0.03075  0.18531  86  MET A N   
656  C CA  . MET A 91  ? 0.84615 0.82707 0.51463 0.05412  0.02173  0.17957  86  MET A CA  
657  C C   . MET A 91  ? 0.87079 0.86175 0.55143 0.08214  0.01813  0.20366  86  MET A C   
658  O O   . MET A 91  ? 0.88277 0.88513 0.58522 0.09400  0.01829  0.19781  86  MET A O   
659  C CB  . MET A 91  ? 0.86893 0.89516 0.53367 0.03525  0.01077  0.17249  86  MET A CB  
660  C CG  . MET A 91  ? 0.85099 0.91390 0.53606 0.03647  0.00106  0.16643  86  MET A CG  
661  S SD  . MET A 91  ? 0.83315 0.87855 0.53444 0.02813  0.00589  0.13541  86  MET A SD  
662  C CE  . MET A 91  ? 0.87571 0.92111 0.56180 0.00251  0.00752  0.11283  86  MET A CE  
663  N N   . THR A 92  ? 0.89456 0.88379 0.56208 0.09400  0.01524  0.23201  87  THR A N   
664  C CA  . THR A 92  ? 0.93696 0.93799 0.62049 0.12645  0.01252  0.25731  87  THR A CA  
665  C C   . THR A 92  ? 0.95771 0.90762 0.64955 0.14770  0.02880  0.25111  87  THR A C   
666  O O   . THR A 92  ? 0.95985 0.92769 0.67606 0.17036  0.03067  0.25349  87  THR A O   
667  C CB  . THR A 92  ? 1.00407 1.00659 0.66952 0.13672  0.00570  0.29226  87  THR A CB  
668  O OG1 . THR A 92  ? 0.98508 1.05109 0.64651 0.12025  -0.01201 0.30047  87  THR A OG1 
669  C CG2 . THR A 92  ? 1.04302 1.03835 0.72556 0.17823  0.00789  0.31977  87  THR A CG2 
670  N N   . ASN A 93  ? 0.96905 0.85730 0.63954 0.13811  0.04183  0.24149  88  ASN A N   
671  C CA  . ASN A 93  ? 0.98834 0.82218 0.65932 0.15301  0.05835  0.23270  88  ASN A CA  
672  C C   . ASN A 93  ? 0.94011 0.78483 0.62773 0.14421  0.06169  0.20331  88  ASN A C   
673  O O   . ASN A 93  ? 0.98206 0.80132 0.67559 0.16029  0.07342  0.19634  88  ASN A O   
674  C CB  . ASN A 93  ? 1.06145 0.82783 0.70107 0.13867  0.07040  0.23090  88  ASN A CB  
675  C CG  . ASN A 93  ? 1.15728 0.90872 0.77454 0.14314  0.06679  0.26228  88  ASN A CG  
676  O OD1 . ASN A 93  ? 1.16994 0.94562 0.77348 0.12009  0.05848  0.26593  88  ASN A OD1 
677  N ND2 . ASN A 93  ? 1.20628 0.91667 0.81833 0.17364  0.07372  0.28569  88  ASN A ND2 
678  N N   . ARG A 94  ? 0.85858 0.73785 0.55165 0.11946  0.05240  0.18626  89  ARG A N   
679  C CA  . ARG A 94  ? 0.78810 0.67956 0.49624 0.11203  0.05288  0.16330  89  ARG A CA  
680  C C   . ARG A 94  ? 0.80178 0.74017 0.53374 0.12773  0.04703  0.16961  89  ARG A C   
681  O O   . ARG A 94  ? 0.82614 0.76238 0.56831 0.13415  0.05367  0.15881  89  ARG A O   
682  C CB  . ARG A 94  ? 0.74146 0.64914 0.44854 0.08418  0.04553  0.14498  89  ARG A CB  
683  C CG  . ARG A 94  ? 0.76836 0.63746 0.46170 0.06717  0.05386  0.13009  89  ARG A CG  
684  C CD  . ARG A 94  ? 0.75035 0.64225 0.44987 0.04608  0.04727  0.11263  89  ARG A CD  
685  N NE  . ARG A 94  ? 0.80052 0.71173 0.49121 0.03638  0.04313  0.11827  89  ARG A NE  
686  C CZ  . ARG A 94  ? 0.79173 0.72979 0.48797 0.02326  0.03726  0.10547  89  ARG A CZ  
687  N NH1 . ARG A 94  ? 0.72306 0.66915 0.43533 0.02029  0.03338  0.08942  89  ARG A NH1 
688  N NH2 . ARG A 94  ? 0.80061 0.75460 0.48378 0.01309  0.03593  0.10893  89  ARG A NH2 
689  N N   . ILE A 95  ? 0.77668 0.76210 0.51646 0.13114  0.03468  0.18691  90  ILE A N   
690  C CA  . ILE A 95  ? 0.76639 0.80529 0.53110 0.14388  0.02883  0.19491  90  ILE A CA  
691  C C   . ILE A 95  ? 0.83160 0.85895 0.60857 0.17877  0.04112  0.20804  90  ILE A C   
692  O O   . ILE A 95  ? 0.82035 0.87092 0.61701 0.18945  0.04661  0.20258  90  ILE A O   
693  C CB  . ILE A 95  ? 0.68288 0.77852 0.45090 0.13602  0.01162  0.21106  90  ILE A CB  
694  C CG1 . ILE A 95  ? 0.63512 0.74232 0.39303 0.10187  0.00273  0.19147  90  ILE A CG1 
695  C CG2 . ILE A 95  ? 0.68553 0.84302 0.48190 0.15192  0.00579  0.22523  90  ILE A CG2 
696  C CD1 . ILE A 95  ? 0.68025 0.81873 0.42390 0.08685  -0.01032 0.20233  90  ILE A CD1 
697  N N   . ASP A 96  ? 0.85504 0.84305 0.61903 0.19710  0.04738  0.22505  91  ASP A N   
698  C CA  . ASP A 96  ? 0.90294 0.86437 0.67547 0.23349  0.06267  0.23539  91  ASP A CA  
699  C C   . ASP A 96  ? 0.89328 0.81406 0.66169 0.23176  0.08054  0.20846  91  ASP A C   
700  O O   . ASP A 96  ? 0.88987 0.82814 0.67761 0.25245  0.09063  0.20519  91  ASP A O   
701  C CB  . ASP A 96  ? 0.97941 0.88531 0.72982 0.24821  0.06775  0.25597  91  ASP A CB  
702  C CG  . ASP A 96  ? 1.01113 0.96086 0.76607 0.25763  0.05055  0.28911  91  ASP A CG  
703  O OD1 . ASP A 96  ? 0.99205 1.01885 0.77092 0.25644  0.03582  0.29610  91  ASP A OD1 
704  O OD2 . ASP A 96  ? 1.08003 0.98760 0.81193 0.26326  0.05120  0.30892  91  ASP A OD2 
705  N N   . ARG A 97  ? 0.89162 0.76303 0.63465 0.20572  0.08478  0.18885  92  ARG A N   
706  C CA  . ARG A 97  ? 0.90897 0.74220 0.64255 0.19894  0.09967  0.16353  92  ARG A CA  
707  C C   . ARG A 97  ? 0.83077 0.71448 0.58422 0.19254  0.09621  0.15044  92  ARG A C   
708  O O   . ARG A 97  ? 0.80980 0.68826 0.56797 0.20599  0.11051  0.14102  92  ARG A O   
709  C CB  . ARG A 97  ? 0.93145 0.72236 0.63915 0.16710  0.09941  0.14708  92  ARG A CB  
710  C CG  . ARG A 97  ? 1.00239 0.71994 0.68428 0.16666  0.11843  0.13473  92  ARG A CG  
711  C CD  . ARG A 97  ? 1.01624 0.72933 0.69897 0.16739  0.12985  0.11322  92  ARG A CD  
712  N NE  . ARG A 97  ? 0.97569 0.72014 0.66185 0.13844  0.11848  0.09606  92  ARG A NE  
713  C CZ  . ARG A 97  ? 0.94666 0.70057 0.63293 0.13259  0.12313  0.07947  92  ARG A CZ  
714  N NH1 . ARG A 97  ? 0.99543 0.73206 0.67857 0.15275  0.14125  0.07424  92  ARG A NH1 
715  N NH2 . ARG A 97  ? 0.88583 0.66604 0.57451 0.10758  0.11039  0.06868  92  ARG A NH2 
716  N N   . LEU A 98  ? 0.79146 0.72236 0.55429 0.17121  0.07855  0.14966  93  LEU A N   
717  C CA  . LEU A 98  ? 0.78559 0.75984 0.56328 0.16049  0.07396  0.13944  93  LEU A CA  
718  C C   . LEU A 98  ? 0.78656 0.81152 0.59053 0.18425  0.07758  0.15206  93  LEU A C   
719  O O   . LEU A 98  ? 0.76701 0.81613 0.58023 0.18115  0.08283  0.14233  93  LEU A O   
720  C CB  . LEU A 98  ? 0.75301 0.75725 0.53206 0.13335  0.05533  0.13684  93  LEU A CB  
721  C CG  . LEU A 98  ? 0.75754 0.72482 0.51813 0.11031  0.05197  0.12212  93  LEU A CG  
722  C CD1 . LEU A 98  ? 0.73719 0.73307 0.50112 0.08948  0.03633  0.11954  93  LEU A CD1 
723  C CD2 . LEU A 98  ? 0.74906 0.68936 0.50116 0.10147  0.05952  0.10407  93  LEU A CD2 
724  N N   . GLU A 99  ? 0.81542 0.86217 0.63244 0.20741  0.07449  0.17507  94  GLU A N   
725  C CA  . GLU A 99  ? 0.82841 0.93269 0.67661 0.23341  0.07794  0.18908  94  GLU A CA  
726  C C   . GLU A 99  ? 0.84810 0.91996 0.69924 0.26376  0.10280  0.18261  94  GLU A C   
727  O O   . GLU A 99  ? 0.84072 0.95491 0.71377 0.27533  0.11226  0.17903  94  GLU A O   
728  C CB  . GLU A 99  ? 0.88006 1.02204 0.74242 0.25062  0.06504  0.21858  94  GLU A CB  
729  C CG  . GLU A 99  ? 0.92051 1.14536 0.82174 0.27145  0.06236  0.23531  94  GLU A CG  
730  C CD  . GLU A 99  ? 0.95417 1.22050 0.86906 0.28931  0.04720  0.26777  94  GLU A CD  
731  O OE1 . GLU A 99  ? 0.97675 1.19490 0.86882 0.29339  0.04380  0.27890  94  GLU A OE1 
732  O OE2 . GLU A 99  ? 0.95582 1.30651 0.90344 0.29710  0.03806  0.28328  94  GLU A OE2 
733  N N   . LYS A 100 ? 0.86447 0.86003 0.69165 0.27501  0.11537  0.17955  95  LYS A N   
734  C CA  . LYS A 100 ? 0.89468 0.84599 0.71726 0.30097  0.14178  0.16851  95  LYS A CA  
735  C C   . LYS A 100 ? 0.87179 0.81578 0.68204 0.27855  0.15216  0.13899  95  LYS A C   
736  O O   . LYS A 100 ? 0.92432 0.86745 0.74029 0.29753  0.17321  0.12820  95  LYS A O   
737  C CB  . LYS A 100 ? 0.93482 0.79667 0.72699 0.30985  0.15247  0.16985  95  LYS A CB  
738  C CG  . LYS A 100 ? 0.99805 0.80458 0.78328 0.34197  0.18184  0.16055  95  LYS A CG  
739  C CD  . LYS A 100 ? 1.05446 0.76242 0.80256 0.34277  0.19239  0.16008  95  LYS A CD  
740  N N   . ALA A 101 ? 0.82331 0.76345 0.61636 0.23934  0.13815  0.12633  96  ALA A N   
741  C CA  . ALA A 101 ? 0.80604 0.74319 0.58553 0.21544  0.14346  0.10270  96  ALA A CA  
742  C C   . ALA A 101 ? 0.76231 0.77307 0.56559 0.20926  0.13826  0.10437  96  ALA A C   
743  O O   . ALA A 101 ? 0.75518 0.76844 0.54745 0.19266  0.14484  0.08778  96  ALA A O   
744  C CB  . ALA A 101 ? 0.77822 0.68661 0.53404 0.17924  0.12910  0.09201  96  ALA A CB  
745  N N   . GLY A 102 ? 0.83052 0.68158 0.67218 0.12246  0.17715  0.10411  97  GLY A N   
746  C CA  . GLY A 102 ? 0.77928 0.69699 0.64998 0.11261  0.17688  0.10155  97  GLY A CA  
747  C C   . GLY A 102 ? 0.71857 0.66383 0.55537 0.07352  0.14310  0.09227  97  GLY A C   
748  O O   . GLY A 102 ? 0.69894 0.68226 0.54414 0.05783  0.14726  0.08184  97  GLY A O   
749  N N   . TRP A 103 ? 0.70491 0.63063 0.50455 0.05827  0.11238  0.09708  98  TRP A N   
750  C CA  . TRP A 103 ? 0.69793 0.63845 0.46063 0.02213  0.08601  0.08917  98  TRP A CA  
751  C C   . TRP A 103 ? 0.68296 0.68741 0.46923 0.01897  0.05205  0.11177  98  TRP A C   
752  O O   . TRP A 103 ? 0.69373 0.72231 0.46006 -0.00983 0.03657  0.10515  98  TRP A O   
753  C CB  . TRP A 103 ? 0.74297 0.61452 0.44188 0.00263  0.07837  0.07946  98  TRP A CB  
754  C CG  . TRP A 103 ? 0.83582 0.64685 0.50015 -0.00625 0.10795  0.05519  98  TRP A CG  
755  C CD1 . TRP A 103 ? 0.80416 0.61868 0.47003 -0.01369 0.13456  0.03487  98  TRP A CD1 
756  C CD2 . TRP A 103 ? 0.89937 0.63684 0.51933 -0.01131 0.11401  0.04915  98  TRP A CD2 
757  N NE1 . TRP A 103 ? 0.85456 0.60026 0.47506 -0.02485 0.15659  0.01547  98  TRP A NE1 
758  C CE2 . TRP A 103 ? 0.89793 0.59616 0.48970 -0.02498 0.14371  0.02397  98  TRP A CE2 
759  C CE3 . TRP A 103 ? 0.93027 0.63140 0.53007 -0.00753 0.09696  0.06329  98  TRP A CE3 
760  C CZ2 . TRP A 103 ? 0.98152 0.60604 0.52288 -0.03849 0.15519  0.01222  98  TRP A CZ2 
761  C CZ3 . TRP A 103 ? 0.98993 0.62021 0.54497 -0.01876 0.10843  0.05293  98  TRP A CZ3 
762  C CH2 . TRP A 103 ? 1.00637 0.59899 0.53112 -0.03582 0.13656  0.02739  98  TRP A CH2 
763  N N   . VAL A 104 ? 0.70360 0.73429 0.52872 0.04577  0.04106  0.13866  99  VAL A N   
764  C CA  . VAL A 104 ? 0.66400 0.76155 0.51287 0.04094  0.00922  0.16187  99  VAL A CA  
765  C C   . VAL A 104 ? 0.68446 0.84443 0.60841 0.07278  0.01526  0.18894  99  VAL A C   
766  O O   . VAL A 104 ? 0.64296 0.78184 0.59710 0.10458  0.04345  0.19363  99  VAL A O   
767  C CB  . VAL A 104 ? 0.65503 0.72823 0.46958 0.03656  -0.01910 0.17535  99  VAL A CB  
768  C CG1 . VAL A 104 ? 0.64227 0.65391 0.38827 0.00861  -0.02154 0.15463  99  VAL A CG1 
769  C CG2 . VAL A 104 ? 0.62014 0.66859 0.45709 0.07216  -0.01328 0.19423  99  VAL A CG2 
770  N N   . GLU A 105 ? 0.68852 0.92592 0.64194 0.06247  -0.01035 0.20875  100 GLU A N   
771  C CA  . GLU A 105 ? 0.72393 1.03494 0.75189 0.08940  -0.01337 0.24456  100 GLU A CA  
772  C C   . GLU A 105 ? 0.69554 1.05803 0.72153 0.07360  -0.05602 0.26981  100 GLU A C   
773  O O   . GLU A 105 ? 0.64452 0.98683 0.61195 0.04016  -0.07868 0.25592  100 GLU A O   
774  C CB  . GLU A 105 ? 0.75171 1.12355 0.83194 0.09081  0.00423  0.24640  100 GLU A CB  
775  C CG  . GLU A 105 ? 0.76946 1.19421 0.83648 0.04978  -0.02059 0.23989  100 GLU A CG  
776  C CD  . GLU A 105 ? 0.78743 1.25770 0.89724 0.04902  0.00142  0.23518  100 GLU A CD  
777  O OE1 . GLU A 105 ? 0.76918 1.22345 0.91408 0.08079  0.03869  0.23488  100 GLU A OE1 
778  O OE2 . GLU A 105 ? 0.81126 1.32974 0.91740 0.01615  -0.01657 0.23163  100 GLU A OE2 
779  N N   . ARG A 106 ? 0.74114 1.17019 0.83085 0.09735  -0.06506 0.30900  101 ARG A N   
780  C CA  . ARG A 106 ? 0.79794 1.27864 0.88782 0.08416  -0.10582 0.33793  101 ARG A CA  
781  C C   . ARG A 106 ? 0.83625 1.42428 0.98265 0.07182  -0.12240 0.36473  101 ARG A C   
782  O O   . ARG A 106 ? 0.85382 1.50260 1.07828 0.10290  -0.11273 0.39958  101 ARG A O   
783  C CB  . ARG A 106 ? 0.80918 1.27858 0.92262 0.12037  -0.10752 0.36720  101 ARG A CB  
784  C CG  . ARG A 106 ? 0.82380 1.19455 0.87299 0.12322  -0.10318 0.34561  101 ARG A CG  
785  C CD  . ARG A 106 ? 0.85429 1.20097 0.93938 0.16845  -0.08663 0.36835  101 ARG A CD  
786  N NE  . ARG A 106 ? 0.85878 1.13473 0.88901 0.16812  -0.09656 0.36166  101 ARG A NE  
787  C CZ  . ARG A 106 ? 0.88833 1.10533 0.92270 0.19940  -0.07509 0.36397  101 ARG A CZ  
788  N NH1 . ARG A 106 ? 0.89948 1.05199 0.88462 0.19047  -0.08460 0.34920  101 ARG A NH1 
789  N NH2 . ARG A 106 ? 0.93049 1.14430 1.01693 0.23345  -0.03943 0.37055  101 ARG A NH2 
790  N N   . ARG A 107 ? 0.87942 1.49033 0.98732 0.02595  -0.14571 0.35047  102 ARG A N   
791  C CA  . ARG A 107 ? 0.88767 1.59973 1.03598 0.00286  -0.16941 0.37541  102 ARG A CA  
792  C C   . ARG A 107 ? 0.94187 1.67097 1.06674 -0.02043 -0.20349 0.39099  102 ARG A C   
793  O O   . ARG A 107 ? 1.01132 1.68003 1.10471 -0.00957 -0.20424 0.38543  102 ARG A O   
794  C CB  . ARG A 107 ? 0.86936 1.58076 0.98551 -0.03695 -0.16671 0.34303  102 ARG A CB  
795  N N   . ALA A 108 ? 0.99170 2.02999 0.90378 0.06543  -0.12163 0.06404  103 ALA A N   
796  C CA  . ALA A 108 ? 0.98302 2.12046 0.86882 0.07164  -0.15104 0.06032  103 ALA A CA  
797  C C   . ALA A 108 ? 0.96514 2.15094 0.84238 0.01489  -0.17462 -0.00161 103 ALA A C   
798  O O   . ALA A 108 ? 0.95906 2.16557 0.80028 0.00075  -0.18834 -0.02770 103 ALA A O   
799  C CB  . ALA A 108 ? 0.98996 2.25633 0.91531 0.11736  -0.15946 0.11169  103 ALA A CB  
800  N N   . THR A 116 ? 0.98590 2.08043 0.75231 0.12095  -0.15486 0.08029  111 THR A N   
801  C CA  . THR A 116 ? 0.98676 1.98605 0.74597 0.14835  -0.13166 0.10899  111 THR A CA  
802  C C   . THR A 116 ? 0.94794 1.83485 0.67083 0.11217  -0.12751 0.06532  111 THR A C   
803  O O   . THR A 116 ? 0.96408 1.80834 0.64959 0.09245  -0.13246 0.03357  111 THR A O   
804  C CB  . THR A 116 ? 1.04655 2.01225 0.79516 0.19647  -0.11035 0.15314  111 THR A CB  
805  O OG1 . THR A 116 ? 1.09242 2.13774 0.88715 0.23901  -0.10087 0.20729  111 THR A OG1 
806  C CG2 . THR A 116 ? 1.01649 1.86154 0.74539 0.21155  -0.08347 0.16263  111 THR A CG2 
807  N N   . LEU A 117 ? 0.88329 1.69950 0.63579 0.10044  -0.10866 0.06258  112 LEU A N   
808  C CA  . LEU A 117 ? 0.87178 1.57012 0.60468 0.06791  -0.09808 0.02861  112 LEU A CA  
809  C C   . LEU A 117 ? 0.81912 1.43137 0.56704 0.08905  -0.06689 0.05493  112 LEU A C   
810  O O   . LEU A 117 ? 0.79932 1.44320 0.58814 0.11267  -0.05168 0.08671  112 LEU A O   
811  C CB  . LEU A 117 ? 0.89911 1.60577 0.65033 0.01662  -0.10804 -0.01304 112 LEU A CB  
812  C CG  . LEU A 117 ? 0.93168 1.73092 0.67930 -0.01525 -0.13453 -0.05116 112 LEU A CG  
813  C CD1 . LEU A 117 ? 0.93693 1.74323 0.71716 -0.06227 -0.13516 -0.08664 112 LEU A CD1 
814  C CD2 . LEU A 117 ? 0.95859 1.72039 0.65954 -0.03067 -0.14111 -0.08316 112 LEU A CD2 
815  N N   . VAL A 118 ? 0.78891 1.29692 0.50697 0.07981  -0.05579 0.03980  113 VAL A N   
816  C CA  . VAL A 118 ? 0.74280 1.16958 0.47105 0.08710  -0.02782 0.05175  113 VAL A CA  
817  C C   . VAL A 118 ? 0.72152 1.09564 0.44802 0.04363  -0.03013 0.02241  113 VAL A C   
818  O O   . VAL A 118 ? 0.75042 1.09120 0.45092 0.01763  -0.04376 -0.00612 113 VAL A O   
819  C CB  . VAL A 118 ? 0.73735 1.09360 0.43569 0.11175  -0.01231 0.05968  113 VAL A CB  
820  C CG1 . VAL A 118 ? 0.70467 0.98969 0.41546 0.11433  0.01687  0.06552  113 VAL A CG1 
821  C CG2 . VAL A 118 ? 0.74265 1.14991 0.44178 0.15549  -0.00684 0.09260  113 VAL A CG2 
822  N N   . ALA A 119 ? 0.70498 1.07172 0.46142 0.03564  -0.01378 0.03044  114 ALA A N   
823  C CA  . ALA A 119 ? 0.69577 1.02561 0.45343 -0.00527 -0.01453 0.00906  114 ALA A CA  
824  C C   . ALA A 119 ? 0.69924 0.96687 0.45795 -0.00603 0.01063  0.01871  114 ALA A C   
825  O O   . ALA A 119 ? 0.70753 0.99141 0.49217 0.01489  0.03258  0.03797  114 ALA A O   
826  C CB  . ALA A 119 ? 0.68978 1.09241 0.48400 -0.02673 -0.02229 0.00161  114 ALA A CB  
827  N N   . LEU A 120 ? 0.68876 0.88977 0.42218 -0.03079 0.00928  0.00521  115 LEU A N   
828  C CA  . LEU A 120 ? 0.69637 0.85338 0.42784 -0.04063 0.02926  0.01139  115 LEU A CA  
829  C C   . LEU A 120 ? 0.66707 0.86490 0.43322 -0.05684 0.04188  0.01492  115 LEU A C   
830  O O   . LEU A 120 ? 0.66359 0.89594 0.44585 -0.07901 0.03057  0.00490  115 LEU A O   
831  C CB  . LEU A 120 ? 0.73977 0.83348 0.44227 -0.06634 0.02155  0.00162  115 LEU A CB  
832  C CG  . LEU A 120 ? 0.73984 0.77714 0.41071 -0.05346 0.01589  -0.00062 115 LEU A CG  
833  C CD1 . LEU A 120 ? 0.77395 0.75826 0.42904 -0.07949 0.01084  -0.00324 115 LEU A CD1 
834  C CD2 . LEU A 120 ? 0.71770 0.74027 0.38317 -0.02872 0.03449  0.00971  115 LEU A CD2 
835  N N   . THR A 121 ? 0.66143 0.85709 0.44265 -0.04802 0.06834  0.02521  116 THR A N   
836  C CA  . THR A 121 ? 0.68572 0.90473 0.49464 -0.07049 0.08498  0.02467  116 THR A CA  
837  C C   . THR A 121 ? 0.66417 0.83584 0.44322 -0.10569 0.08449  0.01788  116 THR A C   
838  O O   . THR A 121 ? 0.66030 0.78238 0.40254 -0.10824 0.07278  0.01682  116 THR A O   
839  C CB  . THR A 121 ? 0.70991 0.94305 0.54942 -0.05213 0.11912  0.03372  116 THR A CB  
840  O OG1 . THR A 121 ? 0.74055 0.92269 0.55105 -0.05119 0.13357  0.03021  116 THR A OG1 
841  C CG2 . THR A 121 ? 0.70977 0.98428 0.58059 -0.01113 0.12286  0.04933  116 THR A CG2 
842  N N   . SER A 122 ? 0.67388 0.86302 0.47096 -0.13216 0.09859  0.01593  117 SER A N   
843  C CA  . SER A 122 ? 0.71832 0.86712 0.48558 -0.16383 0.10210  0.01634  117 SER A CA  
844  C C   . SER A 122 ? 0.72511 0.84153 0.46285 -0.15703 0.11509  0.02143  117 SER A C   
845  O O   . SER A 122 ? 0.76701 0.84177 0.46733 -0.16597 0.10498  0.02735  117 SER A O   
846  C CB  . SER A 122 ? 0.76786 0.94547 0.55984 -0.19370 0.11898  0.01311  117 SER A CB  
847  O OG  . SER A 122 ? 0.77281 0.97984 0.59146 -0.18706 0.14740  0.01237  117 SER A OG  
848  N N   . ALA A 123 ? 0.71650 0.85499 0.47546 -0.14105 0.13962  0.01864  118 ALA A N   
849  C CA  . ALA A 123 ? 0.68077 0.79748 0.41686 -0.13616 0.15485  0.01580  118 ALA A CA  
850  C C   . ALA A 123 ? 0.68966 0.77043 0.39866 -0.11209 0.13523  0.01822  118 ALA A C   
851  O O   . ALA A 123 ? 0.67406 0.72768 0.35013 -0.11641 0.13248  0.01823  118 ALA A O   
852  C CB  . ALA A 123 ? 0.63521 0.78143 0.41086 -0.12415 0.19191  0.00721  118 ALA A CB  
853  N N   . GLY A 124 ? 0.67216 0.75800 0.39480 -0.08706 0.12124  0.02033  119 GLY A N   
854  C CA  . GLY A 124 ? 0.66975 0.72116 0.36707 -0.06646 0.10373  0.02040  119 GLY A CA  
855  C C   . GLY A 124 ? 0.65788 0.67159 0.32333 -0.08386 0.07830  0.02253  119 GLY A C   
856  O O   . GLY A 124 ? 0.66622 0.64353 0.30586 -0.07706 0.07104  0.02327  119 GLY A O   
857  N N   . ARG A 125 ? 0.67585 0.69776 0.34848 -0.10610 0.06736  0.02324  120 ARG A N   
858  C CA  . ARG A 125 ? 0.70577 0.68694 0.35748 -0.12368 0.05070  0.02673  120 ARG A CA  
859  C C   . ARG A 125 ? 0.80154 0.75648 0.42706 -0.13657 0.05711  0.04052  120 ARG A C   
860  O O   . ARG A 125 ? 0.73772 0.65372 0.34206 -0.13150 0.04613  0.04845  120 ARG A O   
861  C CB  . ARG A 125 ? 0.72503 0.72281 0.39656 -0.14906 0.04611  0.02161  120 ARG A CB  
862  C CG  . ARG A 125 ? 0.82653 0.77891 0.48813 -0.16792 0.03576  0.02318  120 ARG A CG  
863  C CD  . ARG A 125 ? 0.86140 0.80402 0.52196 -0.19847 0.04775  0.03626  120 ARG A CD  
864  N NE  . ARG A 125 ? 0.91478 0.81094 0.57538 -0.21625 0.04476  0.04097  120 ARG A NE  
865  C CZ  . ARG A 125 ? 0.94170 0.84086 0.62645 -0.24332 0.05083  0.03059  120 ARG A CZ  
866  N NH1 . ARG A 125 ? 0.93613 0.88860 0.64515 -0.25516 0.05591  0.01511  120 ARG A NH1 
867  N NH2 . ARG A 125 ? 0.97278 0.82214 0.66305 -0.25865 0.05480  0.03515  120 ARG A NH2 
868  N N   . ALA A 126 ? 0.79252 0.77430 0.42048 -0.15312 0.07553  0.04391  121 ALA A N   
869  C CA  . ALA A 126 ? 0.79678 0.76921 0.39567 -0.16746 0.08135  0.05749  121 ALA A CA  
870  C C   . ALA A 126 ? 0.78340 0.74845 0.36443 -0.14671 0.08104  0.05433  121 ALA A C   
871  O O   . ALA A 126 ? 0.79445 0.74064 0.34897 -0.14841 0.07128  0.06871  121 ALA A O   
872  C CB  . ALA A 126 ? 0.80206 0.81320 0.40732 -0.19120 0.10480  0.05525  121 ALA A CB  
873  N N   . LEU A 127 ? 0.76823 0.75001 0.36716 -0.12606 0.09341  0.03705  122 LEU A N   
874  C CA  . LEU A 127 ? 0.75452 0.72979 0.34196 -0.10794 0.09802  0.02868  122 LEU A CA  
875  C C   . LEU A 127 ? 0.75438 0.68763 0.32493 -0.09187 0.07303  0.03592  122 LEU A C   
876  O O   . LEU A 127 ? 0.75476 0.67882 0.30445 -0.09055 0.06690  0.04127  122 LEU A O   
877  C CB  . LEU A 127 ? 0.71688 0.70933 0.33380 -0.08644 0.12047  0.01137  122 LEU A CB  
878  C CG  . LEU A 127 ? 0.72401 0.70461 0.33644 -0.06544 0.12955  -0.00162 122 LEU A CG  
879  C CD1 . LEU A 127 ? 0.78306 0.78418 0.37965 -0.08344 0.14393  -0.01179 122 LEU A CD1 
880  C CD2 . LEU A 127 ? 0.71042 0.70054 0.35735 -0.04140 0.15488  -0.01203 122 LEU A CD2 
881  N N   . ILE A 128 ? 0.74849 0.66131 0.33000 -0.08084 0.05896  0.03487  123 ILE A N   
882  C CA  . ILE A 128 ? 0.74788 0.61969 0.31874 -0.06647 0.04011  0.03645  123 ILE A CA  
883  C C   . ILE A 128 ? 0.77758 0.62132 0.33564 -0.08277 0.02662  0.05646  123 ILE A C   
884  O O   . ILE A 128 ? 0.77474 0.58906 0.32326 -0.07227 0.01616  0.06374  123 ILE A O   
885  C CB  . ILE A 128 ? 0.71831 0.58383 0.30324 -0.05319 0.03163  0.02513  123 ILE A CB  
886  C CG1 . ILE A 128 ? 0.69893 0.52246 0.27442 -0.03863 0.01764  0.02086  123 ILE A CG1 
887  C CG2 . ILE A 128 ? 0.70745 0.58343 0.30578 -0.07430 0.02503  0.02638  123 ILE A CG2 
888  C CD1 . ILE A 128 ? 0.71458 0.52917 0.28040 -0.01856 0.02438  0.01614  123 ILE A CD1 
889  N N   . ASP A 129 ? 0.75611 0.60782 0.31773 -0.10731 0.02920  0.06778  124 ASP A N   
890  C CA  . ASP A 129 ? 0.79778 0.62139 0.34998 -0.12181 0.02250  0.09332  124 ASP A CA  
891  C C   . ASP A 129 ? 0.83565 0.67069 0.36321 -0.11939 0.02208  0.11230  124 ASP A C   
892  O O   . ASP A 129 ? 0.85980 0.66772 0.38045 -0.11442 0.01173  0.13593  124 ASP A O   
893  C CB  . ASP A 129 ? 0.84019 0.67408 0.40073 -0.15025 0.03123  0.10128  124 ASP A CB  
894  C CG  . ASP A 129 ? 0.85183 0.66161 0.43731 -0.15863 0.02727  0.09015  124 ASP A CG  
895  O OD1 . ASP A 129 ? 0.83955 0.61549 0.43205 -0.14590 0.01759  0.08291  124 ASP A OD1 
896  O OD2 . ASP A 129 ? 0.84303 0.67090 0.44320 -0.18057 0.03578  0.08534  124 ASP A OD2 
897  N N   . ASP A 130 ? 0.82628 0.70639 0.34422 -0.12314 0.03502  0.10138  125 ASP A N   
898  C CA  . ASP A 130 ? 0.82845 0.73614 0.32236 -0.12421 0.03540  0.11129  125 ASP A CA  
899  C C   . ASP A 130 ? 0.81402 0.71135 0.30843 -0.09807 0.02729  0.09908  125 ASP A C   
900  O O   . ASP A 130 ? 0.80854 0.70586 0.28982 -0.09133 0.01468  0.11738  125 ASP A O   
901  C CB  . ASP A 130 ? 0.85981 0.82190 0.34870 -0.14239 0.05791  0.09448  125 ASP A CB  
902  C CG  . ASP A 130 ? 0.96052 0.96597 0.43383 -0.15031 0.05807  0.10323  125 ASP A CG  
903  O OD1 . ASP A 130 ? 1.01727 1.01409 0.47426 -0.14200 0.03960  0.12940  125 ASP A OD1 
904  O OD2 . ASP A 130 ? 0.97140 1.02094 0.46032 -0.16134 0.07631  0.08235  125 ASP A OD2 
905  N N   . ALA A 131 ? 0.74639 0.63674 0.25804 -0.08183 0.03511  0.07055  126 ALA A N   
906  C CA  . ALA A 131 ? 0.76559 0.64877 0.27885 -0.05902 0.03375  0.05441  126 ALA A CA  
907  C C   . ALA A 131 ? 0.81009 0.64725 0.32490 -0.04318 0.01229  0.06820  126 ALA A C   
908  O O   . ALA A 131 ? 0.80616 0.64404 0.31692 -0.03035 0.00551  0.06839  126 ALA A O   
909  C CB  . ALA A 131 ? 0.71714 0.59932 0.24964 -0.04400 0.05072  0.02662  126 ALA A CB  
910  N N   . VAL A 132 ? 0.84195 0.64159 0.36744 -0.04520 0.00385  0.07645  127 VAL A N   
911  C CA  . VAL A 132 ? 0.86359 0.61541 0.39896 -0.03115 -0.00988 0.08216  127 VAL A CA  
912  C C   . VAL A 132 ? 0.87236 0.61808 0.40285 -0.03110 -0.02053 0.11549  127 VAL A C   
913  O O   . VAL A 132 ? 0.93557 0.65713 0.47530 -0.01324 -0.02942 0.11954  127 VAL A O   
914  C CB  . VAL A 132 ? 0.83054 0.55018 0.38213 -0.03901 -0.01170 0.07669  127 VAL A CB  
915  C CG1 . VAL A 132 ? 0.81643 0.53258 0.37068 -0.06281 -0.01030 0.10057  127 VAL A CG1 
916  C CG2 . VAL A 132 ? 0.86344 0.53524 0.42961 -0.02490 -0.01938 0.06959  127 VAL A CG2 
917  N N   . VAL A 133 ? 0.86949 0.64045 0.38675 -0.04958 -0.01897 0.14213  128 VAL A N   
918  C CA  . VAL A 133 ? 0.88967 0.66735 0.39944 -0.04678 -0.02907 0.18155  128 VAL A CA  
919  C C   . VAL A 133 ? 0.86731 0.68668 0.36597 -0.03255 -0.03531 0.17399  128 VAL A C   
920  O O   . VAL A 133 ? 0.89445 0.70294 0.40308 -0.01401 -0.04782 0.19100  128 VAL A O   
921  C CB  . VAL A 133 ? 0.91829 0.72364 0.40982 -0.07095 -0.02365 0.21181  128 VAL A CB  
922  C CG1 . VAL A 133 ? 0.93928 0.77142 0.41625 -0.06559 -0.03459 0.25642  128 VAL A CG1 
923  C CG2 . VAL A 133 ? 0.96323 0.72128 0.47306 -0.08457 -0.01655 0.22232  128 VAL A CG2 
924  N N   . ALA A 134 ? 0.81995 0.68962 0.30349 -0.04182 -0.02388 0.14601  129 ALA A N   
925  C CA  . ALA A 134 ? 0.83355 0.74827 0.31043 -0.03294 -0.02536 0.13036  129 ALA A CA  
926  C C   . ALA A 134 ? 0.81330 0.69097 0.31150 -0.00775 -0.02756 0.10557  129 ALA A C   
927  O O   . ALA A 134 ? 0.81713 0.71560 0.31876 0.00540  -0.03540 0.10271  129 ALA A O   
928  C CB  . ALA A 134 ? 0.78402 0.75598 0.24819 -0.05192 -0.00419 0.09863  129 ALA A CB  
929  N N   . HIS A 135 ? 0.80593 0.63407 0.31844 -0.00158 -0.02093 0.08766  130 HIS A N   
930  C CA  . HIS A 135 ? 0.78807 0.58006 0.31722 0.02054  -0.02065 0.06386  130 HIS A CA  
931  C C   . HIS A 135 ? 0.79628 0.55290 0.34098 0.03595  -0.03794 0.08551  130 HIS A C   
932  O O   . HIS A 135 ? 0.77058 0.52971 0.32504 0.05273  -0.04148 0.07456  130 HIS A O   
933  C CB  . HIS A 135 ? 0.78986 0.54725 0.32654 0.02165  -0.01146 0.04499  130 HIS A CB  
934  C CG  . HIS A 135 ? 0.80968 0.52729 0.35923 0.04202  -0.01149 0.02441  130 HIS A CG  
935  N ND1 . HIS A 135 ? 0.79295 0.51900 0.34520 0.05712  -0.00149 0.00006  130 HIS A ND1 
936  C CD2 . HIS A 135 ? 0.82473 0.49576 0.38558 0.04713  -0.01731 0.02146  130 HIS A CD2 
937  C CE1 . HIS A 135 ? 0.78961 0.47413 0.35154 0.07217  -0.00218 -0.01383 130 HIS A CE1 
938  N NE2 . HIS A 135 ? 0.81198 0.46481 0.37844 0.06566  -0.01212 -0.00237 130 HIS A NE2 
939  N N   . VAL A 136 ? 0.80420 0.52645 0.35740 0.03033  -0.04532 0.11522  131 VAL A N   
940  C CA  . VAL A 136 ? 0.88680 0.56677 0.46575 0.04593  -0.05527 0.13582  131 VAL A CA  
941  C C   . VAL A 136 ? 0.89662 0.61703 0.47521 0.05622  -0.06820 0.16778  131 VAL A C   
942  O O   . VAL A 136 ? 0.86345 0.56875 0.46602 0.07679  -0.07586 0.17389  131 VAL A O   
943  C CB  . VAL A 136 ? 0.92986 0.56067 0.52550 0.03493  -0.05241 0.15716  131 VAL A CB  
944  C CG1 . VAL A 136 ? 0.89651 0.49817 0.49548 0.02568  -0.04260 0.12061  131 VAL A CG1 
945  C CG2 . VAL A 136 ? 0.94600 0.60452 0.52515 0.01638  -0.05204 0.19272  131 VAL A CG2 
946  N N   . ASP A 137 ? 0.92326 0.70149 0.47581 0.04172  -0.07079 0.18894  132 ASP A N   
947  C CA  . ASP A 137 ? 0.93056 0.76862 0.47678 0.04993  -0.08484 0.21627  132 ASP A CA  
948  C C   . ASP A 137 ? 0.88977 0.76455 0.43834 0.06074  -0.08507 0.17656  132 ASP A C   
949  O O   . ASP A 137 ? 0.87703 0.77352 0.44205 0.07918  -0.09842 0.18936  132 ASP A O   
950  C CB  . ASP A 137 ? 0.96578 0.86749 0.47732 0.02717  -0.08485 0.23945  132 ASP A CB  
951  N N   . ASN A 138 ? 0.83988 0.72057 0.37777 0.05068  -0.06779 0.12862  133 ASN A N   
952  C CA  . ASN A 138 ? 0.83539 0.74174 0.38043 0.05949  -0.06034 0.08665  133 ASN A CA  
953  C C   . ASN A 138 ? 0.83507 0.68403 0.41044 0.08436  -0.06413 0.07679  133 ASN A C   
954  O O   . ASN A 138 ? 0.82910 0.70259 0.41921 0.09765  -0.06797 0.06250  133 ASN A O   
955  C CB  . ASN A 138 ? 0.83365 0.74636 0.36821 0.04570  -0.03426 0.04306  133 ASN A CB  
956  C CG  . ASN A 138 ? 0.81300 0.75435 0.35753 0.05117  -0.01827 -0.00214 133 ASN A CG  
957  O OD1 . ASN A 138 ? 0.75064 0.74820 0.29768 0.05180  -0.02590 -0.00599 133 ASN A OD1 
958  N ND2 . ASN A 138 ? 0.79766 0.70432 0.34990 0.05512  0.00568  -0.03587 133 ASN A ND2 
959  N N   . GLN A 139 ? 0.82900 0.60564 0.41572 0.08856  -0.06180 0.08107  134 GLN A N   
960  C CA  . GLN A 139 ? 0.82769 0.54821 0.44259 0.10816  -0.06159 0.06693  134 GLN A CA  
961  C C   . GLN A 139 ? 0.87007 0.58965 0.51381 0.12573  -0.07827 0.09993  134 GLN A C   
962  O O   . GLN A 139 ? 0.90809 0.62085 0.57545 0.14330  -0.07915 0.08280  134 GLN A O   
963  C CB  . GLN A 139 ? 0.80642 0.46109 0.42608 0.10319  -0.05443 0.06167  134 GLN A CB  
964  C CG  . GLN A 139 ? 0.76698 0.41977 0.36715 0.09458  -0.03822 0.02739  134 GLN A CG  
965  C CD  . GLN A 139 ? 0.83883 0.43590 0.44723 0.09448  -0.03320 0.01314  134 GLN A CD  
966  O OE1 . GLN A 139 ? 0.83893 0.42704 0.44040 0.09945  -0.02146 -0.01688 134 GLN A OE1 
967  N NE2 . GLN A 139 ? 0.85377 0.41643 0.47820 0.08784  -0.03956 0.03435  134 GLN A NE2 
968  N N   . ARG A 140 ? 0.86662 0.59160 0.51287 0.12278  -0.08939 0.14961  135 ARG A N   
969  C CA  . ARG A 140 ? 0.91773 0.64370 0.59768 0.14363  -0.10339 0.19055  135 ARG A CA  
970  C C   . ARG A 140 ? 0.86967 0.67280 0.55031 0.15528  -0.11595 0.18589  135 ARG A C   
971  O O   . ARG A 140 ? 0.92115 0.72052 0.63894 0.17815  -0.12360 0.19303  135 ARG A O   
972  C CB  . ARG A 140 ? 1.01702 0.74570 0.69566 0.13852  -0.10966 0.25068  135 ARG A CB  
973  C CG  . ARG A 140 ? 1.07102 0.72818 0.75463 0.12365  -0.09488 0.25363  135 ARG A CG  
974  C CD  . ARG A 140 ? 1.15765 0.80846 0.85098 0.12232  -0.09622 0.31696  135 ARG A CD  
975  N NE  . ARG A 140 ? 1.20890 0.84663 0.87693 0.09496  -0.08506 0.31685  135 ARG A NE  
976  C CZ  . ARG A 140 ? 1.25232 0.94828 0.87976 0.07792  -0.08897 0.33309  135 ARG A CZ  
977  N NH1 . ARG A 140 ? 1.25962 1.03556 0.86423 0.08349  -0.10403 0.34941  135 ARG A NH1 
978  N NH2 . ARG A 140 ? 1.27612 0.95542 0.88722 0.05320  -0.07677 0.33006  135 ARG A NH2 
979  N N   . ARG A 141 ? 0.84988 0.72719 0.49379 0.13798  -0.11599 0.17003  136 ARG A N   
980  C CA  . ARG A 141 ? 0.91347 0.87519 0.55778 0.14276  -0.12478 0.15482  136 ARG A CA  
981  C C   . ARG A 141 ? 0.84338 0.78327 0.50799 0.15213  -0.11157 0.09842  136 ARG A C   
982  O O   . ARG A 141 ? 0.79865 0.78430 0.48539 0.16537  -0.12003 0.08908  136 ARG A O   
983  C CB  . ARG A 141 ? 0.91364 0.95891 0.51576 0.11572  -0.12133 0.14348  136 ARG A CB  
984  C CG  . ARG A 141 ? 1.01471 1.10561 0.59478 0.10767  -0.13727 0.20310  136 ARG A CG  
985  C CD  . ARG A 141 ? 1.04367 1.22063 0.58105 0.07670  -0.13077 0.18582  136 ARG A CD  
986  N NE  . ARG A 141 ? 1.07313 1.20752 0.58781 0.05445  -0.11149 0.17479  136 ARG A NE  
987  C CZ  . ARG A 141 ? 1.12702 1.24420 0.62511 0.04518  -0.11475 0.21939  136 ARG A CZ  
988  N NH1 . ARG A 141 ? 1.19794 1.33238 0.69869 0.05755  -0.13442 0.28218  136 ARG A NH1 
989  N NH2 . ARG A 141 ? 1.08904 1.17307 0.57142 0.02460  -0.09647 0.20315  136 ARG A NH2 
990  N N   . VAL A 142 ? 0.80867 0.68376 0.46684 0.14582  -0.09042 0.06196  137 VAL A N   
991  C CA  . VAL A 142 ? 0.74546 0.58992 0.42192 0.15623  -0.07471 0.01361  137 VAL A CA  
992  C C   . VAL A 142 ? 0.82739 0.62535 0.54585 0.18053  -0.08385 0.02611  137 VAL A C   
993  O O   . VAL A 142 ? 0.85189 0.65887 0.59485 0.19333  -0.08028 -0.00165 137 VAL A O   
994  C CB  . VAL A 142 ? 0.72124 0.51019 0.37959 0.14657  -0.05114 -0.01761 137 VAL A CB  
995  C CG1 . VAL A 142 ? 0.70242 0.44697 0.37922 0.16022  -0.03463 -0.05775 137 VAL A CG1 
996  C CG2 . VAL A 142 ? 0.70048 0.53931 0.32978 0.12563  -0.03550 -0.03737 137 VAL A CG2 
997  N N   . LEU A 143 ? 0.76549 0.58871 0.50313 0.22832  -0.05375 0.15719  138 LEU A N   
998  C CA  . LEU A 143 ? 0.83799 0.62921 0.58935 0.24355  -0.04883 0.16777  138 LEU A CA  
999  C C   . LEU A 143 ? 0.90939 0.72202 0.66481 0.26315  -0.04869 0.19665  138 LEU A C   
1000 O O   . LEU A 143 ? 0.97046 0.75786 0.74757 0.27030  -0.04092 0.20594  138 LEU A O   
1001 C CB  . LEU A 143 ? 0.85058 0.57962 0.60842 0.23192  -0.03389 0.16938  138 LEU A CB  
1002 C CG  . LEU A 143 ? 0.77738 0.48885 0.53879 0.20678  -0.03335 0.14022  138 LEU A CG  
1003 C CD1 . LEU A 143 ? 0.76305 0.42866 0.52402 0.19333  -0.01975 0.14620  138 LEU A CD1 
1004 C CD2 . LEU A 143 ? 0.79996 0.50273 0.57625 0.20642  -0.03514 0.11960  138 LEU A CD2 
1005 N N   . SER A 144 ? 0.89174 0.75470 0.63156 0.26778  -0.05634 0.20823  139 SER A N   
1006 C CA  . SER A 144 ? 0.93300 0.81871 0.67819 0.28104  -0.05579 0.23690  139 SER A CA  
1007 C C   . SER A 144 ? 0.94050 0.84614 0.70712 0.29749  -0.06282 0.23601  139 SER A C   
1008 O O   . SER A 144 ? 0.98468 0.88783 0.76617 0.30949  -0.05910 0.26028  139 SER A O   
1009 C CB  . SER A 144 ? 0.91265 0.85461 0.63368 0.27995  -0.06317 0.24556  139 SER A CB  
1010 O OG  . SER A 144 ? 0.88319 0.87880 0.59729 0.27952  -0.07720 0.22007  139 SER A OG  
1011 N N   . ALA A 145 ? 0.91226 0.83696 0.68299 0.29858  -0.07236 0.20839  140 ALA A N   
1012 C CA  . ALA A 145 ? 0.90406 0.84738 0.69695 0.31341  -0.07840 0.20424  140 ALA A CA  
1013 C C   . ALA A 145 ? 0.90714 0.79430 0.72598 0.31658  -0.06622 0.20723  140 ALA A C   
1014 O O   . ALA A 145 ? 0.92950 0.82652 0.77098 0.33018  -0.06834 0.21049  140 ALA A O   
1015 C CB  . ALA A 145 ? 0.86087 0.83888 0.65330 0.31218  -0.09013 0.17075  140 ALA A CB  
1016 N N   . LEU A 146 ? 0.88670 0.71816 0.70488 0.30334  -0.05309 0.20400  141 LEU A N   
1017 C CA  . LEU A 146 ? 0.89847 0.67863 0.74250 0.30280  -0.03906 0.20307  141 LEU A CA  
1018 C C   . LEU A 146 ? 0.93806 0.69125 0.79256 0.30389  -0.02595 0.23146  141 LEU A C   
1019 O O   . LEU A 146 ? 0.96261 0.71230 0.79931 0.29581  -0.02267 0.24365  141 LEU A O   
1020 C CB  . LEU A 146 ? 0.86521 0.60355 0.70445 0.28522  -0.03210 0.17617  141 LEU A CB  
1021 C CG  . LEU A 146 ? 0.82766 0.58121 0.66192 0.28330  -0.04205 0.14618  141 LEU A CG  
1022 C CD1 . LEU A 146 ? 0.85479 0.56168 0.68816 0.26589  -0.03296 0.12354  141 LEU A CD1 
1023 C CD2 . LEU A 146 ? 0.82319 0.60113 0.67951 0.29975  -0.04687 0.14295  141 LEU A CD2 
1024 N N   . SER A 147 ? 0.97274 0.70650 0.85834 0.31384  -0.01751 0.24086  142 SER A N   
1025 C CA  . SER A 147 ? 1.03412 0.73636 0.93554 0.31480  -0.00236 0.26458  142 SER A CA  
1026 C C   . SER A 147 ? 1.03604 0.68608 0.93851 0.29477  0.01381  0.24981  142 SER A C   
1027 O O   . SER A 147 ? 1.02303 0.65797 0.91857 0.28164  0.01373  0.22148  142 SER A O   
1028 C CB  . SER A 147 ? 1.06267 0.75533 1.00141 0.33011  0.00389  0.27456  142 SER A CB  
1029 O OG  . SER A 147 ? 1.05634 0.71705 1.01565 0.32335  0.01207  0.24642  142 SER A OG  
1030 N N   . ALA A 148 ? 1.08484 0.70905 0.99629 0.29227  0.02824  0.26906  143 ALA A N   
1031 C CA  . ALA A 148 ? 1.07471 0.65166 0.99188 0.27282  0.04508  0.25414  143 ALA A CA  
1032 C C   . ALA A 148 ? 1.07016 0.61601 1.01245 0.26626  0.05474  0.22637  143 ALA A C   
1033 O O   . ALA A 148 ? 1.02393 0.54610 0.96037 0.24745  0.06016  0.20030  143 ALA A O   
1034 C CB  . ALA A 148 ? 1.07940 0.63476 1.00971 0.27375  0.06163  0.27917  143 ALA A CB  
1035 N N   . ALA A 149 ? 1.09499 0.64281 1.06517 0.28101  0.05707  0.23070  144 ALA A N   
1036 C CA  . ALA A 149 ? 1.10031 0.62214 1.09474 0.27464  0.06708  0.20239  144 ALA A CA  
1037 C C   . ALA A 149 ? 1.08225 0.62126 1.05865 0.26995  0.05349  0.17571  144 ALA A C   
1038 O O   . ALA A 149 ? 1.07939 0.59517 1.05810 0.25426  0.06120  0.14578  144 ALA A O   
1039 C CB  . ALA A 149 ? 1.12722 0.64737 1.15856 0.29228  0.07418  0.21484  144 ALA A CB  
1040 N N   . GLU A 150 ? 1.06013 0.64224 1.01820 0.28272  0.03419  0.18492  145 GLU A N   
1041 C CA  . GLU A 150 ? 1.00689 0.60719 0.94709 0.27887  0.02231  0.15991  145 GLU A CA  
1042 C C   . GLU A 150 ? 1.00389 0.59035 0.91469 0.25844  0.02181  0.14273  145 GLU A C   
1043 O O   . GLU A 150 ? 0.98864 0.56478 0.89191 0.24713  0.02182  0.11506  145 GLU A O   
1044 C CB  . GLU A 150 ? 0.99107 0.64463 0.91864 0.29574  0.00268  0.17188  145 GLU A CB  
1045 C CG  . GLU A 150 ? 1.02150 0.69401 0.97826 0.31469  -0.00026 0.17823  145 GLU A CG  
1046 C CD  . GLU A 150 ? 1.01766 0.74751 0.96365 0.33115  -0.01876 0.19564  145 GLU A CD  
1047 O OE1 . GLU A 150 ? 1.01704 0.76711 0.93942 0.33034  -0.02494 0.21331  145 GLU A OE1 
1048 O OE2 . GLU A 150 ? 1.01531 0.77244 0.97697 0.34376  -0.02662 0.18969  145 GLU A OE2 
1049 N N   . GLN A 151 ? 1.01136 0.59817 0.90513 0.25302  0.02134  0.15892  146 GLN A N   
1050 C CA  . GLN A 151 ? 0.98487 0.55733 0.85425 0.23322  0.02109  0.14381  146 GLN A CA  
1051 C C   . GLN A 151 ? 1.00579 0.53463 0.88849 0.21496  0.03768  0.12260  146 GLN A C   
1052 O O   . GLN A 151 ? 1.00208 0.52159 0.86910 0.19956  0.03536  0.09826  146 GLN A O   
1053 C CB  . GLN A 151 ? 0.99471 0.57510 0.84815 0.23085  0.01990  0.16556  146 GLN A CB  
1054 C CG  . GLN A 151 ? 0.98367 0.61298 0.81948 0.24530  0.00370  0.18258  146 GLN A CG  
1055 C CD  . GLN A 151 ? 1.00585 0.64323 0.82392 0.24077  0.00435  0.20165  146 GLN A CD  
1056 O OE1 . GLN A 151 ? 1.01721 0.62676 0.82929 0.22419  0.01273  0.19595  146 GLN A OE1 
1057 N NE2 . GLN A 151 ? 0.98795 0.66582 0.79766 0.25470  -0.00420 0.22351  146 GLN A NE2 
1058 N N   . ARG A 152 ? 1.01699 0.52122 0.92899 0.21570  0.05439  0.13023  147 ARG A N   
1059 C CA  . ARG A 152 ? 1.02951 0.49707 0.95718 0.19671  0.07181  0.10647  147 ARG A CA  
1060 C C   . ARG A 152 ? 1.01287 0.47687 0.94763 0.19277  0.07337  0.07778  147 ARG A C   
1061 O O   . ARG A 152 ? 1.01168 0.45966 0.93888 0.17240  0.07914  0.05001  147 ARG A O   
1062 C CB  . ARG A 152 ? 1.06693 0.51198 1.02731 0.19952  0.09035  0.12004  147 ARG A CB  
1063 N N   . GLN A 153 ? 1.00385 0.48517 0.95278 0.21106  0.06836  0.08329  148 GLN A N   
1064 C CA  . GLN A 153 ? 0.98839 0.46964 0.94356 0.20770  0.06986  0.05578  148 GLN A CA  
1065 C C   . GLN A 153 ? 0.97662 0.47308 0.89543 0.19952  0.05547  0.03914  148 GLN A C   
1066 O O   . GLN A 153 ? 1.00232 0.48947 0.91462 0.18448  0.05981  0.01057  148 GLN A O   
1067 C CB  . GLN A 153 ? 0.99031 0.48978 0.97048 0.23009  0.06650  0.06685  148 GLN A CB  
1068 C CG  . GLN A 153 ? 0.99032 0.48687 0.98577 0.22652  0.07236  0.03827  148 GLN A CG  
1069 N N   . LEU A 154 ? 0.94705 0.46929 0.84151 0.20807  0.03821  0.05579  149 LEU A N   
1070 C CA  . LEU A 154 ? 0.90999 0.45539 0.77683 0.19668  0.02261  0.04017  149 LEU A CA  
1071 C C   . LEU A 154 ? 0.88232 0.41475 0.73491 0.16933  0.02516  0.02579  149 LEU A C   
1072 O O   . LEU A 154 ? 0.84321 0.39065 0.68428 0.15283  0.01824  0.00582  149 LEU A O   
1073 C CB  . LEU A 154 ? 0.92005 0.50333 0.77254 0.20926  0.00503  0.05839  149 LEU A CB  
1074 C CG  . LEU A 154 ? 0.85242 0.46786 0.68712 0.19527  -0.00993 0.04381  149 LEU A CG  
1075 C CD1 . LEU A 154 ? 0.81382 0.43954 0.65441 0.19078  -0.01141 0.02065  149 LEU A CD1 
1076 C CD2 . LEU A 154 ? 0.84220 0.49651 0.66898 0.20805  -0.02362 0.05837  149 LEU A CD2 
1077 N N   . ALA A 155 ? 0.91552 0.42223 0.77039 0.16447  0.03534  0.03679  150 ALA A N   
1078 C CA  . ALA A 155 ? 0.91422 0.40991 0.75981 0.13816  0.03858  0.02122  150 ALA A CA  
1079 C C   . ALA A 155 ? 0.93876 0.41683 0.79504 0.12148  0.05198  -0.00734 150 ALA A C   
1080 O O   . ALA A 155 ? 0.93827 0.42569 0.78188 0.09858  0.04803  -0.02683 150 ALA A O   
1081 C CB  . ALA A 155 ? 0.92682 0.39899 0.77573 0.13708  0.04835  0.03866  150 ALA A CB  
1082 N N   . LYS A 156 ? 0.96219 0.41787 0.84330 0.13221  0.06832  -0.01029 151 LYS A N   
1083 C CA  . LYS A 156 ? 0.99850 0.44017 0.89196 0.11519  0.08349  -0.04148 151 LYS A CA  
1084 C C   . LYS A 156 ? 0.98096 0.45258 0.85859 0.10789  0.07147  -0.06064 151 LYS A C   
1085 O O   . LYS A 156 ? 0.97262 0.45270 0.83862 0.08396  0.07238  -0.08521 151 LYS A O   
1086 C CB  . LYS A 156 ? 1.01785 0.44241 0.95224 0.12682  0.10183  -0.03922 151 LYS A CB  
1087 C CG  . LYS A 156 ? 1.05847 0.46213 1.01820 0.11862  0.11851  -0.03546 151 LYS A CG  
1088 N N   . LEU A 157 ? 0.96251 0.45330 0.84010 0.12807  0.06056  -0.04931 152 LEU A N   
1089 C CA  . LEU A 157 ? 0.93497 0.45251 0.80121 0.12251  0.05162  -0.06611 152 LEU A CA  
1090 C C   . LEU A 157 ? 0.92099 0.46495 0.75958 0.10485  0.03565  -0.06899 152 LEU A C   
1091 O O   . LEU A 157 ? 0.89745 0.45536 0.72477 0.08755  0.03478  -0.08812 152 LEU A O   
1092 C CB  . LEU A 157 ? 0.90826 0.44326 0.78349 0.14801  0.04319  -0.05321 152 LEU A CB  
1093 C CG  . LEU A 157 ? 0.93959 0.45367 0.84702 0.16716  0.05819  -0.05008 152 LEU A CG  
1094 C CD1 . LEU A 157 ? 0.94154 0.47984 0.85705 0.19419  0.04605  -0.03202 152 LEU A CD1 
1095 C CD2 . LEU A 157 ? 0.93079 0.43388 0.85088 0.15444  0.07402  -0.08049 152 LEU A CD2 
1096 N N   . LEU A 158 ? 0.92756 0.48010 0.75658 0.10879  0.02387  -0.04913 153 LEU A N   
1097 C CA  . LEU A 158 ? 0.89504 0.47194 0.70501 0.09327  0.00995  -0.04981 153 LEU A CA  
1098 C C   . LEU A 158 ? 0.89612 0.46629 0.69821 0.06747  0.01523  -0.06538 153 LEU A C   
1099 O O   . LEU A 158 ? 0.89057 0.48429 0.67913 0.05203  0.00644  -0.07261 153 LEU A O   
1100 C CB  . LEU A 158 ? 0.86997 0.45617 0.67588 0.10197  -0.00078 -0.02781 153 LEU A CB  
1101 C CG  . LEU A 158 ? 0.84813 0.45750 0.65750 0.12271  -0.01051 -0.01580 153 LEU A CG  
1102 C CD1 . LEU A 158 ? 0.82261 0.44072 0.62761 0.12867  -0.01769 0.00317  153 LEU A CD1 
1103 C CD2 . LEU A 158 ? 0.81752 0.45609 0.62392 0.11785  -0.01931 -0.02634 153 LEU A CD2 
1104 N N   . ASP A 159 ? 0.92482 0.46572 0.73755 0.06238  0.03010  -0.07030 154 ASP A N   
1105 C CA  . ASP A 159 ? 0.95143 0.48981 0.75957 0.03622  0.03657  -0.09030 154 ASP A CA  
1106 C C   . ASP A 159 ? 0.93421 0.48482 0.73760 0.02236  0.04207  -0.11635 154 ASP A C   
1107 O O   . ASP A 159 ? 0.92380 0.49922 0.71059 0.00165  0.03521  -0.12821 154 ASP A O   
1108 C CB  . ASP A 159 ? 0.96944 0.47205 0.79669 0.03394  0.05547  -0.09302 154 ASP A CB  
1109 C CG  . ASP A 159 ? 0.97829 0.48249 0.80324 0.00535  0.06205  -0.11623 154 ASP A CG  
1110 O OD1 . ASP A 159 ? 0.98063 0.51602 0.78603 -0.01005 0.04681  -0.12019 154 ASP A OD1 
1111 O OD2 . ASP A 159 ? 1.02899 0.50562 0.87458 -0.00187 0.08307  -0.13072 154 ASP A OD2 
1112 N N   . LYS A 160 ? 0.94567 0.48163 0.76426 0.03369  0.05474  -0.12463 155 LYS A N   
1113 C CA  . LYS A 160 ? 0.96852 0.51590 0.78350 0.02069  0.06240  -0.15095 155 LYS A CA  
1114 C C   . LYS A 160 ? 0.94318 0.52765 0.73507 0.01743  0.04511  -0.14703 155 LYS A C   
1115 O O   . LYS A 160 ? 0.95966 0.56652 0.73525 -0.00331 0.04474  -0.16406 155 LYS A O   
1116 C CB  . LYS A 160 ? 0.98603 0.51067 0.82690 0.03723  0.07875  -0.15720 155 LYS A CB  
1117 C CG  . LYS A 160 ? 1.03353 0.55237 0.88413 0.01940  0.09915  -0.19190 155 LYS A CG  
1118 C CD  . LYS A 160 ? 1.08315 0.57417 0.96904 0.03818  0.11753  -0.19507 155 LYS A CD  
1119 C CE  . LYS A 160 ? 1.12739 0.62162 1.03625 0.01933  0.13682  -0.22485 155 LYS A CE  
1120 N NZ  . LYS A 160 ? 1.15109 0.67573 1.03534 -0.00262 0.13578  -0.25133 155 LYS A NZ  
1121 N N   . LEU A 161 ? 0.92509 0.51884 0.71681 0.03723  0.03180  -0.12462 156 LEU A N   
1122 C CA  . LEU A 161 ? 0.90610 0.53281 0.68274 0.03495  0.01784  -0.11894 156 LEU A CA  
1123 C C   . LEU A 161 ? 0.90105 0.54933 0.66079 0.01661  0.00606  -0.11318 156 LEU A C   
1124 O O   . LEU A 161 ? 0.84053 0.51633 0.58603 0.00385  0.00059  -0.11652 156 LEU A O   
1125 C CB  . LEU A 161 ? 0.87721 0.51003 0.66309 0.05875  0.00821  -0.09932 156 LEU A CB  
1126 C CG  . LEU A 161 ? 0.82467 0.48853 0.60457 0.05935  -0.00277 -0.09320 156 LEU A CG  
1127 C CD1 . LEU A 161 ? 0.83600 0.50921 0.61220 0.05296  0.00523  -0.11033 156 LEU A CD1 
1128 C CD2 . LEU A 161 ? 0.75784 0.42849 0.55134 0.08136  -0.01004 -0.07870 156 LEU A CD2 
1129 N N   . LEU A 162 ? 0.91607 0.55352 0.67871 0.01537  0.00257  -0.10300 157 LEU A N   
1130 C CA  . LEU A 162 ? 0.90830 0.56719 0.66021 0.00003  -0.00952 -0.09556 157 LEU A CA  
1131 C C   . LEU A 162 ? 0.93632 0.60633 0.67666 -0.02564 -0.00483 -0.11622 157 LEU A C   
1132 O O   . LEU A 162 ? 0.93918 0.64151 0.66642 -0.03987 -0.01579 -0.11299 157 LEU A O   
1133 C CB  . LEU A 162 ? 0.91930 0.56317 0.67975 0.00642  -0.01310 -0.08009 157 LEU A CB  
1134 C CG  . LEU A 162 ? 0.91020 0.57574 0.66755 -0.00242 -0.02722 -0.06637 157 LEU A CG  
1135 C CD1 . LEU A 162 ? 0.87483 0.57099 0.63045 0.00091  -0.03871 -0.05522 157 LEU A CD1 
1136 C CD2 . LEU A 162 ? 0.90227 0.55092 0.66964 0.00834  -0.02820 -0.05121 157 LEU A CD2 
1137 N N   . GLN A 163 ? 0.96664 0.61316 0.71424 -0.03214 0.01216  -0.13772 158 GLN A N   
1138 C CA  . GLN A 163 ? 0.98318 0.64474 0.72129 -0.05876 0.01902  -0.16397 158 GLN A CA  
1139 C C   . GLN A 163 ? 1.00441 0.69727 0.72450 -0.06811 0.01728  -0.17438 158 GLN A C   
1140 O O   . GLN A 163 ? 1.02954 0.75692 0.73168 -0.09000 0.01190  -0.18399 158 GLN A O   
1141 C CB  . GLN A 163 ? 0.99083 0.61841 0.74816 -0.06325 0.04205  -0.18783 158 GLN A CB  
1142 C CG  . GLN A 163 ? 1.01243 0.61633 0.78475 -0.06484 0.04662  -0.18347 158 GLN A CG  
1143 N N   . GLY A 164 ? 0.99713 0.68165 0.72168 -0.05185 0.02163  -0.17176 159 GLY A N   
1144 C CA  . GLY A 164 ? 1.00811 0.71929 0.71713 -0.05900 0.02232  -0.18028 159 GLY A CA  
1145 C C   . GLY A 164 ? 1.02174 0.77116 0.71354 -0.06190 0.00434  -0.15839 159 GLY A C   
1146 O O   . GLY A 164 ? 1.04900 0.82259 0.72682 -0.06816 0.00553  -0.16207 159 GLY A O   
1147 N N   . GLN A 165 ? 0.99161 0.74716 0.68672 -0.05762 -0.01047 -0.13513 160 GLN A N   
1148 C CA  . GLN A 165 ? 0.96862 0.75915 0.65572 -0.05902 -0.02592 -0.11144 160 GLN A CA  
1149 C C   . GLN A 165 ? 0.98361 0.80925 0.65423 -0.08242 -0.03464 -0.11267 160 GLN A C   
1150 O O   . GLN A 165 ? 1.02469 0.86291 0.68024 -0.10167 -0.02722 -0.13709 160 GLN A O   
1151 C CB  . GLN A 165 ? 0.90861 0.68940 0.61446 -0.04064 -0.03598 -0.08570 160 GLN A CB  
1152 C CG  . GLN A 165 ? 0.86232 0.61495 0.58472 -0.01751 -0.02950 -0.08442 160 GLN A CG  
1153 C CD  . GLN A 165 ? 0.85771 0.61751 0.57882 -0.01125 -0.02292 -0.08977 160 GLN A CD  
1154 O OE1 . GLN A 165 ? 0.85234 0.63724 0.57200 -0.01192 -0.02801 -0.07686 160 GLN A OE1 
1155 N NE2 . GLN A 165 ? 0.83463 0.57190 0.55991 -0.00488 -0.01005 -0.10817 160 GLN A NE2 
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