data_8YKR
# 
_entry.id   8YKR 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8YKR         pdb_00008ykr 10.2210/pdb8ykr/pdb 
WWPDB D_1300045742 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-19 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8YKR 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-05 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              sjwang@tust.edu.cn 
_pdbx_contact_author.name_first         Shujun 
_pdbx_contact_author.name_last          Wang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4501-8047 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Gu, C.K.'   1 0000-0002-8564-3827 
'Wang, S.J.' 2 0000-0003-4501-8047 
'Zhao, G.H.' 3 0000-0001-8587-9680 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Enhancing the Gastric Stability of Ferritin Nanocage via Computational-Assisted Disulfide Bond Engineering' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Gu, C.K.'   1 0000-0002-8564-3827 
primary 'Wang, S.J.' 2 0000-0003-4501-8047 
primary 'Zhao, G.H.' 3 0000-0001-8587-9680 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Ferritin       19445.004 6  1.16.3.1 'A44C, K72C, H125C, L135C, V139C, D147C, A155C, Y163C' ? ? 
2 non-polymer syn 'FE (III) ION' 55.845    10 ?        ?                                                      ? ? 
3 water       nat water          18.015    59 ?        ?                                                      ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MASQVRQNYHEDCEASINKQINMELYASYVYLSMAYYFERDDVCLPGFAKFFKESSDEEREHAQTFMKYQNCRGGRIVLQ
QIAAPSMREWGTGLEALQAALDLEKQVNQSLLELHSTASGNNDPCLTKLLEDEYCEEQCDSIKKIGCMITKLKRCGPTGL
GECMFDKELN
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MASQVRQNYHEDCEASINKQINMELYASYVYLSMAYYFERDDVCLPGFAKFFKESSDEEREHAQTFMKYQNCRGGRIVLQ
QIAAPSMREWGTGLEALQAALDLEKQVNQSLLELHSTASGNNDPCLTKLLEDEYCEEQCDSIKKIGCMITKLKRCGPTGL
GECMFDKELN
;
_entity_poly.pdbx_strand_id                 B,A,C,D,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'FE (III) ION' FE  
3 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   SER n 
1 4   GLN n 
1 5   VAL n 
1 6   ARG n 
1 7   GLN n 
1 8   ASN n 
1 9   TYR n 
1 10  HIS n 
1 11  GLU n 
1 12  ASP n 
1 13  CYS n 
1 14  GLU n 
1 15  ALA n 
1 16  SER n 
1 17  ILE n 
1 18  ASN n 
1 19  LYS n 
1 20  GLN n 
1 21  ILE n 
1 22  ASN n 
1 23  MET n 
1 24  GLU n 
1 25  LEU n 
1 26  TYR n 
1 27  ALA n 
1 28  SER n 
1 29  TYR n 
1 30  VAL n 
1 31  TYR n 
1 32  LEU n 
1 33  SER n 
1 34  MET n 
1 35  ALA n 
1 36  TYR n 
1 37  TYR n 
1 38  PHE n 
1 39  GLU n 
1 40  ARG n 
1 41  ASP n 
1 42  ASP n 
1 43  VAL n 
1 44  CYS n 
1 45  LEU n 
1 46  PRO n 
1 47  GLY n 
1 48  PHE n 
1 49  ALA n 
1 50  LYS n 
1 51  PHE n 
1 52  PHE n 
1 53  LYS n 
1 54  GLU n 
1 55  SER n 
1 56  SER n 
1 57  ASP n 
1 58  GLU n 
1 59  GLU n 
1 60  ARG n 
1 61  GLU n 
1 62  HIS n 
1 63  ALA n 
1 64  GLN n 
1 65  THR n 
1 66  PHE n 
1 67  MET n 
1 68  LYS n 
1 69  TYR n 
1 70  GLN n 
1 71  ASN n 
1 72  CYS n 
1 73  ARG n 
1 74  GLY n 
1 75  GLY n 
1 76  ARG n 
1 77  ILE n 
1 78  VAL n 
1 79  LEU n 
1 80  GLN n 
1 81  GLN n 
1 82  ILE n 
1 83  ALA n 
1 84  ALA n 
1 85  PRO n 
1 86  SER n 
1 87  MET n 
1 88  ARG n 
1 89  GLU n 
1 90  TRP n 
1 91  GLY n 
1 92  THR n 
1 93  GLY n 
1 94  LEU n 
1 95  GLU n 
1 96  ALA n 
1 97  LEU n 
1 98  GLN n 
1 99  ALA n 
1 100 ALA n 
1 101 LEU n 
1 102 ASP n 
1 103 LEU n 
1 104 GLU n 
1 105 LYS n 
1 106 GLN n 
1 107 VAL n 
1 108 ASN n 
1 109 GLN n 
1 110 SER n 
1 111 LEU n 
1 112 LEU n 
1 113 GLU n 
1 114 LEU n 
1 115 HIS n 
1 116 SER n 
1 117 THR n 
1 118 ALA n 
1 119 SER n 
1 120 GLY n 
1 121 ASN n 
1 122 ASN n 
1 123 ASP n 
1 124 PRO n 
1 125 CYS n 
1 126 LEU n 
1 127 THR n 
1 128 LYS n 
1 129 LEU n 
1 130 LEU n 
1 131 GLU n 
1 132 ASP n 
1 133 GLU n 
1 134 TYR n 
1 135 CYS n 
1 136 GLU n 
1 137 GLU n 
1 138 GLN n 
1 139 CYS n 
1 140 ASP n 
1 141 SER n 
1 142 ILE n 
1 143 LYS n 
1 144 LYS n 
1 145 ILE n 
1 146 GLY n 
1 147 CYS n 
1 148 MET n 
1 149 ILE n 
1 150 THR n 
1 151 LYS n 
1 152 LEU n 
1 153 LYS n 
1 154 ARG n 
1 155 CYS n 
1 156 GLY n 
1 157 PRO n 
1 158 THR n 
1 159 GLY n 
1 160 LEU n 
1 161 GLY n 
1 162 GLU n 
1 163 CYS n 
1 164 MET n 
1 165 PHE n 
1 166 ASP n 
1 167 LYS n 
1 168 GLU n 
1 169 LEU n 
1 170 ASN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   170 
_entity_src_gen.gene_src_common_name               'Kuruma prawn, Marsupenaeus japonicus' 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Penaeus japonicus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     27405 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
FE  non-polymer         . 'FE (III) ION'  ? 'Fe 3'           55.845  
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   B . n 
A 1 2   ALA 2   2   2   ALA ALA B . n 
A 1 3   SER 3   3   3   SER SER B . n 
A 1 4   GLN 4   4   4   GLN GLN B . n 
A 1 5   VAL 5   5   5   VAL VAL B . n 
A 1 6   ARG 6   6   6   ARG ARG B . n 
A 1 7   GLN 7   7   7   GLN GLN B . n 
A 1 8   ASN 8   8   8   ASN ASN B . n 
A 1 9   TYR 9   9   9   TYR TYR B . n 
A 1 10  HIS 10  10  10  HIS HIS B . n 
A 1 11  GLU 11  11  11  GLU GLU B . n 
A 1 12  ASP 12  12  12  ASP ASP B . n 
A 1 13  CYS 13  13  13  CYS CYS B . n 
A 1 14  GLU 14  14  14  GLU GLU B . n 
A 1 15  ALA 15  15  15  ALA ALA B . n 
A 1 16  SER 16  16  16  SER SER B . n 
A 1 17  ILE 17  17  17  ILE ILE B . n 
A 1 18  ASN 18  18  18  ASN ASN B . n 
A 1 19  LYS 19  19  19  LYS LYS B . n 
A 1 20  GLN 20  20  20  GLN GLN B . n 
A 1 21  ILE 21  21  21  ILE ILE B . n 
A 1 22  ASN 22  22  22  ASN ASN B . n 
A 1 23  MET 23  23  23  MET MET B . n 
A 1 24  GLU 24  24  24  GLU GLU B . n 
A 1 25  LEU 25  25  25  LEU LEU B . n 
A 1 26  TYR 26  26  26  TYR TYR B . n 
A 1 27  ALA 27  27  27  ALA ALA B . n 
A 1 28  SER 28  28  28  SER SER B . n 
A 1 29  TYR 29  29  29  TYR TYR B . n 
A 1 30  VAL 30  30  30  VAL VAL B . n 
A 1 31  TYR 31  31  31  TYR TYR B . n 
A 1 32  LEU 32  32  32  LEU LEU B . n 
A 1 33  SER 33  33  33  SER SER B . n 
A 1 34  MET 34  34  34  MET MET B . n 
A 1 35  ALA 35  35  35  ALA ALA B . n 
A 1 36  TYR 36  36  36  TYR TYR B . n 
A 1 37  TYR 37  37  37  TYR TYR B . n 
A 1 38  PHE 38  38  38  PHE PHE B . n 
A 1 39  GLU 39  39  39  GLU GLU B . n 
A 1 40  ARG 40  40  40  ARG ARG B . n 
A 1 41  ASP 41  41  41  ASP ASP B . n 
A 1 42  ASP 42  42  42  ASP ASP B . n 
A 1 43  VAL 43  43  43  VAL VAL B . n 
A 1 44  CYS 44  44  44  CYS CYS B . n 
A 1 45  LEU 45  45  45  LEU LEU B . n 
A 1 46  PRO 46  46  46  PRO PRO B . n 
A 1 47  GLY 47  47  47  GLY GLY B . n 
A 1 48  PHE 48  48  48  PHE PHE B . n 
A 1 49  ALA 49  49  49  ALA ALA B . n 
A 1 50  LYS 50  50  50  LYS LYS B . n 
A 1 51  PHE 51  51  51  PHE PHE B . n 
A 1 52  PHE 52  52  52  PHE PHE B . n 
A 1 53  LYS 53  53  53  LYS LYS B . n 
A 1 54  GLU 54  54  54  GLU GLU B . n 
A 1 55  SER 55  55  55  SER SER B . n 
A 1 56  SER 56  56  56  SER SER B . n 
A 1 57  ASP 57  57  57  ASP ASP B . n 
A 1 58  GLU 58  58  58  GLU GLU B . n 
A 1 59  GLU 59  59  59  GLU GLU B . n 
A 1 60  ARG 60  60  60  ARG ARG B . n 
A 1 61  GLU 61  61  61  GLU GLU B . n 
A 1 62  HIS 62  62  62  HIS HIS B . n 
A 1 63  ALA 63  63  63  ALA ALA B . n 
A 1 64  GLN 64  64  64  GLN GLN B . n 
A 1 65  THR 65  65  65  THR THR B . n 
A 1 66  PHE 66  66  66  PHE PHE B . n 
A 1 67  MET 67  67  67  MET MET B . n 
A 1 68  LYS 68  68  68  LYS LYS B . n 
A 1 69  TYR 69  69  69  TYR TYR B . n 
A 1 70  GLN 70  70  70  GLN GLN B . n 
A 1 71  ASN 71  71  71  ASN ASN B . n 
A 1 72  CYS 72  72  72  CYS CYS B . n 
A 1 73  ARG 73  73  73  ARG ARG B . n 
A 1 74  GLY 74  74  74  GLY GLY B . n 
A 1 75  GLY 75  75  75  GLY GLY B . n 
A 1 76  ARG 76  76  76  ARG ARG B . n 
A 1 77  ILE 77  77  77  ILE ILE B . n 
A 1 78  VAL 78  78  78  VAL VAL B . n 
A 1 79  LEU 79  79  79  LEU LEU B . n 
A 1 80  GLN 80  80  80  GLN GLN B . n 
A 1 81  GLN 81  81  81  GLN GLN B . n 
A 1 82  ILE 82  82  82  ILE ILE B . n 
A 1 83  ALA 83  83  83  ALA ALA B . n 
A 1 84  ALA 84  84  84  ALA ALA B . n 
A 1 85  PRO 85  85  85  PRO PRO B . n 
A 1 86  SER 86  86  86  SER SER B . n 
A 1 87  MET 87  87  87  MET MET B . n 
A 1 88  ARG 88  88  88  ARG ARG B . n 
A 1 89  GLU 89  89  89  GLU GLU B . n 
A 1 90  TRP 90  90  90  TRP TRP B . n 
A 1 91  GLY 91  91  91  GLY GLY B . n 
A 1 92  THR 92  92  92  THR THR B . n 
A 1 93  GLY 93  93  93  GLY GLY B . n 
A 1 94  LEU 94  94  94  LEU LEU B . n 
A 1 95  GLU 95  95  95  GLU GLU B . n 
A 1 96  ALA 96  96  96  ALA ALA B . n 
A 1 97  LEU 97  97  97  LEU LEU B . n 
A 1 98  GLN 98  98  98  GLN GLN B . n 
A 1 99  ALA 99  99  99  ALA ALA B . n 
A 1 100 ALA 100 100 100 ALA ALA B . n 
A 1 101 LEU 101 101 101 LEU LEU B . n 
A 1 102 ASP 102 102 102 ASP ASP B . n 
A 1 103 LEU 103 103 103 LEU LEU B . n 
A 1 104 GLU 104 104 104 GLU GLU B . n 
A 1 105 LYS 105 105 105 LYS LYS B . n 
A 1 106 GLN 106 106 106 GLN GLN B . n 
A 1 107 VAL 107 107 107 VAL VAL B . n 
A 1 108 ASN 108 108 108 ASN ASN B . n 
A 1 109 GLN 109 109 109 GLN GLN B . n 
A 1 110 SER 110 110 110 SER SER B . n 
A 1 111 LEU 111 111 111 LEU LEU B . n 
A 1 112 LEU 112 112 112 LEU LEU B . n 
A 1 113 GLU 113 113 113 GLU GLU B . n 
A 1 114 LEU 114 114 114 LEU LEU B . n 
A 1 115 HIS 115 115 115 HIS HIS B . n 
A 1 116 SER 116 116 116 SER SER B . n 
A 1 117 THR 117 117 117 THR THR B . n 
A 1 118 ALA 118 118 118 ALA ALA B . n 
A 1 119 SER 119 119 119 SER SER B . n 
A 1 120 GLY 120 120 120 GLY GLY B . n 
A 1 121 ASN 121 121 121 ASN ASN B . n 
A 1 122 ASN 122 122 122 ASN ASN B . n 
A 1 123 ASP 123 123 123 ASP ASP B . n 
A 1 124 PRO 124 124 124 PRO PRO B . n 
A 1 125 CYS 125 125 125 CYS CYS B . n 
A 1 126 LEU 126 126 126 LEU LEU B . n 
A 1 127 THR 127 127 127 THR THR B . n 
A 1 128 LYS 128 128 128 LYS LYS B . n 
A 1 129 LEU 129 129 129 LEU LEU B . n 
A 1 130 LEU 130 130 130 LEU LEU B . n 
A 1 131 GLU 131 131 131 GLU GLU B . n 
A 1 132 ASP 132 132 132 ASP ASP B . n 
A 1 133 GLU 133 133 133 GLU GLU B . n 
A 1 134 TYR 134 134 134 TYR TYR B . n 
A 1 135 CYS 135 135 135 CYS CYS B . n 
A 1 136 GLU 136 136 136 GLU GLU B . n 
A 1 137 GLU 137 137 137 GLU GLU B . n 
A 1 138 GLN 138 138 138 GLN GLN B . n 
A 1 139 CYS 139 139 139 CYS CYS B . n 
A 1 140 ASP 140 140 140 ASP ASP B . n 
A 1 141 SER 141 141 141 SER SER B . n 
A 1 142 ILE 142 142 142 ILE ILE B . n 
A 1 143 LYS 143 143 143 LYS LYS B . n 
A 1 144 LYS 144 144 144 LYS LYS B . n 
A 1 145 ILE 145 145 145 ILE ILE B . n 
A 1 146 GLY 146 146 146 GLY GLY B . n 
A 1 147 CYS 147 147 147 CYS CYS B . n 
A 1 148 MET 148 148 148 MET MET B . n 
A 1 149 ILE 149 149 149 ILE ILE B . n 
A 1 150 THR 150 150 150 THR THR B . n 
A 1 151 LYS 151 151 151 LYS LYS B . n 
A 1 152 LEU 152 152 152 LEU LEU B . n 
A 1 153 LYS 153 153 153 LYS LYS B . n 
A 1 154 ARG 154 154 154 ARG ARG B . n 
A 1 155 CYS 155 155 155 CYS CYS B . n 
A 1 156 GLY 156 156 156 GLY GLY B . n 
A 1 157 PRO 157 157 157 PRO PRO B . n 
A 1 158 THR 158 158 158 THR THR B . n 
A 1 159 GLY 159 159 159 GLY GLY B . n 
A 1 160 LEU 160 160 160 LEU LEU B . n 
A 1 161 GLY 161 161 161 GLY GLY B . n 
A 1 162 GLU 162 162 162 GLU GLU B . n 
A 1 163 CYS 163 163 163 CYS CYS B . n 
A 1 164 MET 164 164 164 MET MET B . n 
A 1 165 PHE 165 165 165 PHE PHE B . n 
A 1 166 ASP 166 166 166 ASP ASP B . n 
A 1 167 LYS 167 167 167 LYS LYS B . n 
A 1 168 GLU 168 168 168 GLU GLU B . n 
A 1 169 LEU 169 169 169 LEU LEU B . n 
A 1 170 ASN 170 170 170 ASN ASN B . n 
B 1 1   MET 1   1   ?   ?   ?   A . n 
B 1 2   ALA 2   2   2   ALA ALA A . n 
B 1 3   SER 3   3   3   SER SER A . n 
B 1 4   GLN 4   4   4   GLN GLN A . n 
B 1 5   VAL 5   5   5   VAL VAL A . n 
B 1 6   ARG 6   6   6   ARG ARG A . n 
B 1 7   GLN 7   7   7   GLN GLN A . n 
B 1 8   ASN 8   8   8   ASN ASN A . n 
B 1 9   TYR 9   9   9   TYR TYR A . n 
B 1 10  HIS 10  10  10  HIS HIS A . n 
B 1 11  GLU 11  11  11  GLU GLU A . n 
B 1 12  ASP 12  12  12  ASP ASP A . n 
B 1 13  CYS 13  13  13  CYS CYS A . n 
B 1 14  GLU 14  14  14  GLU GLU A . n 
B 1 15  ALA 15  15  15  ALA ALA A . n 
B 1 16  SER 16  16  16  SER SER A . n 
B 1 17  ILE 17  17  17  ILE ILE A . n 
B 1 18  ASN 18  18  18  ASN ASN A . n 
B 1 19  LYS 19  19  19  LYS LYS A . n 
B 1 20  GLN 20  20  20  GLN GLN A . n 
B 1 21  ILE 21  21  21  ILE ILE A . n 
B 1 22  ASN 22  22  22  ASN ASN A . n 
B 1 23  MET 23  23  23  MET MET A . n 
B 1 24  GLU 24  24  24  GLU GLU A . n 
B 1 25  LEU 25  25  25  LEU LEU A . n 
B 1 26  TYR 26  26  26  TYR TYR A . n 
B 1 27  ALA 27  27  27  ALA ALA A . n 
B 1 28  SER 28  28  28  SER SER A . n 
B 1 29  TYR 29  29  29  TYR TYR A . n 
B 1 30  VAL 30  30  30  VAL VAL A . n 
B 1 31  TYR 31  31  31  TYR TYR A . n 
B 1 32  LEU 32  32  32  LEU LEU A . n 
B 1 33  SER 33  33  33  SER SER A . n 
B 1 34  MET 34  34  34  MET MET A . n 
B 1 35  ALA 35  35  35  ALA ALA A . n 
B 1 36  TYR 36  36  36  TYR TYR A . n 
B 1 37  TYR 37  37  37  TYR TYR A . n 
B 1 38  PHE 38  38  38  PHE PHE A . n 
B 1 39  GLU 39  39  39  GLU GLU A . n 
B 1 40  ARG 40  40  40  ARG ARG A . n 
B 1 41  ASP 41  41  41  ASP ASP A . n 
B 1 42  ASP 42  42  42  ASP ASP A . n 
B 1 43  VAL 43  43  43  VAL VAL A . n 
B 1 44  CYS 44  44  44  CYS CYS A . n 
B 1 45  LEU 45  45  45  LEU LEU A . n 
B 1 46  PRO 46  46  46  PRO PRO A . n 
B 1 47  GLY 47  47  47  GLY GLY A . n 
B 1 48  PHE 48  48  48  PHE PHE A . n 
B 1 49  ALA 49  49  49  ALA ALA A . n 
B 1 50  LYS 50  50  50  LYS LYS A . n 
B 1 51  PHE 51  51  51  PHE PHE A . n 
B 1 52  PHE 52  52  52  PHE PHE A . n 
B 1 53  LYS 53  53  53  LYS LYS A . n 
B 1 54  GLU 54  54  54  GLU GLU A . n 
B 1 55  SER 55  55  55  SER SER A . n 
B 1 56  SER 56  56  56  SER SER A . n 
B 1 57  ASP 57  57  57  ASP ASP A . n 
B 1 58  GLU 58  58  58  GLU GLU A . n 
B 1 59  GLU 59  59  59  GLU GLU A . n 
B 1 60  ARG 60  60  60  ARG ARG A . n 
B 1 61  GLU 61  61  61  GLU GLU A . n 
B 1 62  HIS 62  62  62  HIS HIS A . n 
B 1 63  ALA 63  63  63  ALA ALA A . n 
B 1 64  GLN 64  64  64  GLN GLN A . n 
B 1 65  THR 65  65  65  THR THR A . n 
B 1 66  PHE 66  66  66  PHE PHE A . n 
B 1 67  MET 67  67  67  MET MET A . n 
B 1 68  LYS 68  68  68  LYS LYS A . n 
B 1 69  TYR 69  69  69  TYR TYR A . n 
B 1 70  GLN 70  70  70  GLN GLN A . n 
B 1 71  ASN 71  71  71  ASN ASN A . n 
B 1 72  CYS 72  72  72  CYS CYS A . n 
B 1 73  ARG 73  73  73  ARG ARG A . n 
B 1 74  GLY 74  74  74  GLY GLY A . n 
B 1 75  GLY 75  75  75  GLY GLY A . n 
B 1 76  ARG 76  76  76  ARG ARG A . n 
B 1 77  ILE 77  77  77  ILE ILE A . n 
B 1 78  VAL 78  78  78  VAL VAL A . n 
B 1 79  LEU 79  79  79  LEU LEU A . n 
B 1 80  GLN 80  80  80  GLN GLN A . n 
B 1 81  GLN 81  81  81  GLN GLN A . n 
B 1 82  ILE 82  82  82  ILE ILE A . n 
B 1 83  ALA 83  83  83  ALA ALA A . n 
B 1 84  ALA 84  84  84  ALA ALA A . n 
B 1 85  PRO 85  85  85  PRO PRO A . n 
B 1 86  SER 86  86  86  SER SER A . n 
B 1 87  MET 87  87  87  MET MET A . n 
B 1 88  ARG 88  88  88  ARG ARG A . n 
B 1 89  GLU 89  89  89  GLU GLU A . n 
B 1 90  TRP 90  90  90  TRP TRP A . n 
B 1 91  GLY 91  91  91  GLY GLY A . n 
B 1 92  THR 92  92  92  THR THR A . n 
B 1 93  GLY 93  93  93  GLY GLY A . n 
B 1 94  LEU 94  94  94  LEU LEU A . n 
B 1 95  GLU 95  95  95  GLU GLU A . n 
B 1 96  ALA 96  96  96  ALA ALA A . n 
B 1 97  LEU 97  97  97  LEU LEU A . n 
B 1 98  GLN 98  98  98  GLN GLN A . n 
B 1 99  ALA 99  99  99  ALA ALA A . n 
B 1 100 ALA 100 100 100 ALA ALA A . n 
B 1 101 LEU 101 101 101 LEU LEU A . n 
B 1 102 ASP 102 102 102 ASP ASP A . n 
B 1 103 LEU 103 103 103 LEU LEU A . n 
B 1 104 GLU 104 104 104 GLU GLU A . n 
B 1 105 LYS 105 105 105 LYS LYS A . n 
B 1 106 GLN 106 106 106 GLN GLN A . n 
B 1 107 VAL 107 107 107 VAL VAL A . n 
B 1 108 ASN 108 108 108 ASN ASN A . n 
B 1 109 GLN 109 109 109 GLN GLN A . n 
B 1 110 SER 110 110 110 SER SER A . n 
B 1 111 LEU 111 111 111 LEU LEU A . n 
B 1 112 LEU 112 112 112 LEU LEU A . n 
B 1 113 GLU 113 113 113 GLU GLU A . n 
B 1 114 LEU 114 114 114 LEU LEU A . n 
B 1 115 HIS 115 115 115 HIS HIS A . n 
B 1 116 SER 116 116 116 SER SER A . n 
B 1 117 THR 117 117 117 THR THR A . n 
B 1 118 ALA 118 118 118 ALA ALA A . n 
B 1 119 SER 119 119 119 SER SER A . n 
B 1 120 GLY 120 120 120 GLY GLY A . n 
B 1 121 ASN 121 121 121 ASN ASN A . n 
B 1 122 ASN 122 122 122 ASN ASN A . n 
B 1 123 ASP 123 123 123 ASP ASP A . n 
B 1 124 PRO 124 124 124 PRO PRO A . n 
B 1 125 CYS 125 125 125 CYS CYS A . n 
B 1 126 LEU 126 126 126 LEU LEU A . n 
B 1 127 THR 127 127 127 THR THR A . n 
B 1 128 LYS 128 128 128 LYS LYS A . n 
B 1 129 LEU 129 129 129 LEU LEU A . n 
B 1 130 LEU 130 130 130 LEU LEU A . n 
B 1 131 GLU 131 131 131 GLU GLU A . n 
B 1 132 ASP 132 132 132 ASP ASP A . n 
B 1 133 GLU 133 133 133 GLU GLU A . n 
B 1 134 TYR 134 134 134 TYR TYR A . n 
B 1 135 CYS 135 135 135 CYS CYS A . n 
B 1 136 GLU 136 136 136 GLU GLU A . n 
B 1 137 GLU 137 137 137 GLU GLU A . n 
B 1 138 GLN 138 138 138 GLN GLN A . n 
B 1 139 CYS 139 139 139 CYS CYS A . n 
B 1 140 ASP 140 140 140 ASP ASP A . n 
B 1 141 SER 141 141 141 SER SER A . n 
B 1 142 ILE 142 142 142 ILE ILE A . n 
B 1 143 LYS 143 143 143 LYS LYS A . n 
B 1 144 LYS 144 144 144 LYS LYS A . n 
B 1 145 ILE 145 145 145 ILE ILE A . n 
B 1 146 GLY 146 146 146 GLY GLY A . n 
B 1 147 CYS 147 147 147 CYS CYS A . n 
B 1 148 MET 148 148 148 MET MET A . n 
B 1 149 ILE 149 149 149 ILE ILE A . n 
B 1 150 THR 150 150 150 THR THR A . n 
B 1 151 LYS 151 151 151 LYS LYS A . n 
B 1 152 LEU 152 152 152 LEU LEU A . n 
B 1 153 LYS 153 153 153 LYS LYS A . n 
B 1 154 ARG 154 154 154 ARG ARG A . n 
B 1 155 CYS 155 155 155 CYS CYS A . n 
B 1 156 GLY 156 156 156 GLY GLY A . n 
B 1 157 PRO 157 157 157 PRO PRO A . n 
B 1 158 THR 158 158 158 THR THR A . n 
B 1 159 GLY 159 159 159 GLY GLY A . n 
B 1 160 LEU 160 160 160 LEU LEU A . n 
B 1 161 GLY 161 161 161 GLY GLY A . n 
B 1 162 GLU 162 162 162 GLU GLU A . n 
B 1 163 CYS 163 163 163 CYS CYS A . n 
B 1 164 MET 164 164 164 MET MET A . n 
B 1 165 PHE 165 165 165 PHE PHE A . n 
B 1 166 ASP 166 166 166 ASP ASP A . n 
B 1 167 LYS 167 167 167 LYS LYS A . n 
B 1 168 GLU 168 168 168 GLU GLU A . n 
B 1 169 LEU 169 169 169 LEU LEU A . n 
B 1 170 ASN 170 170 170 ASN ASN A . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   ALA 2   2   ?   ?   ?   C . n 
C 1 3   SER 3   3   3   SER SER C . n 
C 1 4   GLN 4   4   4   GLN GLN C . n 
C 1 5   VAL 5   5   5   VAL VAL C . n 
C 1 6   ARG 6   6   6   ARG ARG C . n 
C 1 7   GLN 7   7   7   GLN GLN C . n 
C 1 8   ASN 8   8   8   ASN ASN C . n 
C 1 9   TYR 9   9   9   TYR TYR C . n 
C 1 10  HIS 10  10  10  HIS HIS C . n 
C 1 11  GLU 11  11  11  GLU GLU C . n 
C 1 12  ASP 12  12  12  ASP ASP C . n 
C 1 13  CYS 13  13  13  CYS CYS C . n 
C 1 14  GLU 14  14  14  GLU GLU C . n 
C 1 15  ALA 15  15  15  ALA ALA C . n 
C 1 16  SER 16  16  16  SER SER C . n 
C 1 17  ILE 17  17  17  ILE ILE C . n 
C 1 18  ASN 18  18  18  ASN ASN C . n 
C 1 19  LYS 19  19  19  LYS LYS C . n 
C 1 20  GLN 20  20  20  GLN GLN C . n 
C 1 21  ILE 21  21  21  ILE ILE C . n 
C 1 22  ASN 22  22  22  ASN ASN C . n 
C 1 23  MET 23  23  23  MET MET C . n 
C 1 24  GLU 24  24  24  GLU GLU C . n 
C 1 25  LEU 25  25  25  LEU LEU C . n 
C 1 26  TYR 26  26  26  TYR TYR C . n 
C 1 27  ALA 27  27  27  ALA ALA C . n 
C 1 28  SER 28  28  28  SER SER C . n 
C 1 29  TYR 29  29  29  TYR TYR C . n 
C 1 30  VAL 30  30  30  VAL VAL C . n 
C 1 31  TYR 31  31  31  TYR TYR C . n 
C 1 32  LEU 32  32  32  LEU LEU C . n 
C 1 33  SER 33  33  33  SER SER C . n 
C 1 34  MET 34  34  34  MET MET C . n 
C 1 35  ALA 35  35  35  ALA ALA C . n 
C 1 36  TYR 36  36  36  TYR TYR C . n 
C 1 37  TYR 37  37  37  TYR TYR C . n 
C 1 38  PHE 38  38  38  PHE PHE C . n 
C 1 39  GLU 39  39  39  GLU GLU C . n 
C 1 40  ARG 40  40  40  ARG ARG C . n 
C 1 41  ASP 41  41  41  ASP ASP C . n 
C 1 42  ASP 42  42  42  ASP ASP C . n 
C 1 43  VAL 43  43  43  VAL VAL C . n 
C 1 44  CYS 44  44  44  CYS CYS C . n 
C 1 45  LEU 45  45  45  LEU LEU C . n 
C 1 46  PRO 46  46  46  PRO PRO C . n 
C 1 47  GLY 47  47  47  GLY GLY C . n 
C 1 48  PHE 48  48  48  PHE PHE C . n 
C 1 49  ALA 49  49  49  ALA ALA C . n 
C 1 50  LYS 50  50  50  LYS LYS C . n 
C 1 51  PHE 51  51  51  PHE PHE C . n 
C 1 52  PHE 52  52  52  PHE PHE C . n 
C 1 53  LYS 53  53  53  LYS LYS C . n 
C 1 54  GLU 54  54  54  GLU GLU C . n 
C 1 55  SER 55  55  55  SER SER C . n 
C 1 56  SER 56  56  56  SER SER C . n 
C 1 57  ASP 57  57  57  ASP ASP C . n 
C 1 58  GLU 58  58  58  GLU GLU C . n 
C 1 59  GLU 59  59  59  GLU GLU C . n 
C 1 60  ARG 60  60  60  ARG ARG C . n 
C 1 61  GLU 61  61  61  GLU GLU C . n 
C 1 62  HIS 62  62  62  HIS HIS C . n 
C 1 63  ALA 63  63  63  ALA ALA C . n 
C 1 64  GLN 64  64  64  GLN GLN C . n 
C 1 65  THR 65  65  65  THR THR C . n 
C 1 66  PHE 66  66  66  PHE PHE C . n 
C 1 67  MET 67  67  67  MET MET C . n 
C 1 68  LYS 68  68  68  LYS LYS C . n 
C 1 69  TYR 69  69  69  TYR TYR C . n 
C 1 70  GLN 70  70  70  GLN GLN C . n 
C 1 71  ASN 71  71  71  ASN ASN C . n 
C 1 72  CYS 72  72  72  CYS CYS C . n 
C 1 73  ARG 73  73  73  ARG ARG C . n 
C 1 74  GLY 74  74  74  GLY GLY C . n 
C 1 75  GLY 75  75  75  GLY GLY C . n 
C 1 76  ARG 76  76  76  ARG ARG C . n 
C 1 77  ILE 77  77  77  ILE ILE C . n 
C 1 78  VAL 78  78  78  VAL VAL C . n 
C 1 79  LEU 79  79  79  LEU LEU C . n 
C 1 80  GLN 80  80  80  GLN GLN C . n 
C 1 81  GLN 81  81  81  GLN GLN C . n 
C 1 82  ILE 82  82  82  ILE ILE C . n 
C 1 83  ALA 83  83  83  ALA ALA C . n 
C 1 84  ALA 84  84  84  ALA ALA C . n 
C 1 85  PRO 85  85  85  PRO PRO C . n 
C 1 86  SER 86  86  86  SER SER C . n 
C 1 87  MET 87  87  87  MET MET C . n 
C 1 88  ARG 88  88  88  ARG ARG C . n 
C 1 89  GLU 89  89  89  GLU GLU C . n 
C 1 90  TRP 90  90  90  TRP TRP C . n 
C 1 91  GLY 91  91  91  GLY GLY C . n 
C 1 92  THR 92  92  92  THR THR C . n 
C 1 93  GLY 93  93  93  GLY GLY C . n 
C 1 94  LEU 94  94  94  LEU LEU C . n 
C 1 95  GLU 95  95  95  GLU GLU C . n 
C 1 96  ALA 96  96  96  ALA ALA C . n 
C 1 97  LEU 97  97  97  LEU LEU C . n 
C 1 98  GLN 98  98  98  GLN GLN C . n 
C 1 99  ALA 99  99  99  ALA ALA C . n 
C 1 100 ALA 100 100 100 ALA ALA C . n 
C 1 101 LEU 101 101 101 LEU LEU C . n 
C 1 102 ASP 102 102 102 ASP ASP C . n 
C 1 103 LEU 103 103 103 LEU LEU C . n 
C 1 104 GLU 104 104 104 GLU GLU C . n 
C 1 105 LYS 105 105 105 LYS LYS C . n 
C 1 106 GLN 106 106 106 GLN GLN C . n 
C 1 107 VAL 107 107 107 VAL VAL C . n 
C 1 108 ASN 108 108 108 ASN ASN C . n 
C 1 109 GLN 109 109 109 GLN GLN C . n 
C 1 110 SER 110 110 110 SER SER C . n 
C 1 111 LEU 111 111 111 LEU LEU C . n 
C 1 112 LEU 112 112 112 LEU LEU C . n 
C 1 113 GLU 113 113 113 GLU GLU C . n 
C 1 114 LEU 114 114 114 LEU LEU C . n 
C 1 115 HIS 115 115 115 HIS HIS C . n 
C 1 116 SER 116 116 116 SER SER C . n 
C 1 117 THR 117 117 117 THR THR C . n 
C 1 118 ALA 118 118 118 ALA ALA C . n 
C 1 119 SER 119 119 119 SER SER C . n 
C 1 120 GLY 120 120 120 GLY GLY C . n 
C 1 121 ASN 121 121 121 ASN ASN C . n 
C 1 122 ASN 122 122 122 ASN ASN C . n 
C 1 123 ASP 123 123 123 ASP ASP C . n 
C 1 124 PRO 124 124 124 PRO PRO C . n 
C 1 125 CYS 125 125 125 CYS CYS C . n 
C 1 126 LEU 126 126 126 LEU LEU C . n 
C 1 127 THR 127 127 127 THR THR C . n 
C 1 128 LYS 128 128 128 LYS LYS C . n 
C 1 129 LEU 129 129 129 LEU LEU C . n 
C 1 130 LEU 130 130 130 LEU LEU C . n 
C 1 131 GLU 131 131 131 GLU GLU C . n 
C 1 132 ASP 132 132 132 ASP ASP C . n 
C 1 133 GLU 133 133 133 GLU GLU C . n 
C 1 134 TYR 134 134 134 TYR TYR C . n 
C 1 135 CYS 135 135 135 CYS CYS C . n 
C 1 136 GLU 136 136 136 GLU GLU C . n 
C 1 137 GLU 137 137 137 GLU GLU C . n 
C 1 138 GLN 138 138 138 GLN GLN C . n 
C 1 139 CYS 139 139 139 CYS CYS C . n 
C 1 140 ASP 140 140 140 ASP ASP C . n 
C 1 141 SER 141 141 141 SER SER C . n 
C 1 142 ILE 142 142 142 ILE ILE C . n 
C 1 143 LYS 143 143 143 LYS LYS C . n 
C 1 144 LYS 144 144 144 LYS LYS C . n 
C 1 145 ILE 145 145 145 ILE ILE C . n 
C 1 146 GLY 146 146 146 GLY GLY C . n 
C 1 147 CYS 147 147 147 CYS CYS C . n 
C 1 148 MET 148 148 148 MET MET C . n 
C 1 149 ILE 149 149 149 ILE ILE C . n 
C 1 150 THR 150 150 150 THR THR C . n 
C 1 151 LYS 151 151 151 LYS LYS C . n 
C 1 152 LEU 152 152 152 LEU LEU C . n 
C 1 153 LYS 153 153 153 LYS LYS C . n 
C 1 154 ARG 154 154 154 ARG ARG C . n 
C 1 155 CYS 155 155 155 CYS CYS C . n 
C 1 156 GLY 156 156 156 GLY GLY C . n 
C 1 157 PRO 157 157 157 PRO PRO C . n 
C 1 158 THR 158 158 158 THR THR C . n 
C 1 159 GLY 159 159 159 GLY GLY C . n 
C 1 160 LEU 160 160 160 LEU LEU C . n 
C 1 161 GLY 161 161 161 GLY GLY C . n 
C 1 162 GLU 162 162 162 GLU GLU C . n 
C 1 163 CYS 163 163 163 CYS CYS C . n 
C 1 164 MET 164 164 164 MET MET C . n 
C 1 165 PHE 165 165 165 PHE PHE C . n 
C 1 166 ASP 166 166 166 ASP ASP C . n 
C 1 167 LYS 167 167 167 LYS LYS C . n 
C 1 168 GLU 168 168 168 GLU GLU C . n 
C 1 169 LEU 169 169 169 LEU LEU C . n 
C 1 170 ASN 170 170 170 ASN ASN C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   ALA 2   2   2   ALA ALA D . n 
D 1 3   SER 3   3   3   SER SER D . n 
D 1 4   GLN 4   4   4   GLN GLN D . n 
D 1 5   VAL 5   5   5   VAL VAL D . n 
D 1 6   ARG 6   6   6   ARG ARG D . n 
D 1 7   GLN 7   7   7   GLN GLN D . n 
D 1 8   ASN 8   8   8   ASN ASN D . n 
D 1 9   TYR 9   9   9   TYR TYR D . n 
D 1 10  HIS 10  10  10  HIS HIS D . n 
D 1 11  GLU 11  11  11  GLU GLU D . n 
D 1 12  ASP 12  12  12  ASP ASP D . n 
D 1 13  CYS 13  13  13  CYS CYS D . n 
D 1 14  GLU 14  14  14  GLU GLU D . n 
D 1 15  ALA 15  15  15  ALA ALA D . n 
D 1 16  SER 16  16  16  SER SER D . n 
D 1 17  ILE 17  17  17  ILE ILE D . n 
D 1 18  ASN 18  18  18  ASN ASN D . n 
D 1 19  LYS 19  19  19  LYS LYS D . n 
D 1 20  GLN 20  20  20  GLN GLN D . n 
D 1 21  ILE 21  21  21  ILE ILE D . n 
D 1 22  ASN 22  22  22  ASN ASN D . n 
D 1 23  MET 23  23  23  MET MET D . n 
D 1 24  GLU 24  24  24  GLU GLU D . n 
D 1 25  LEU 25  25  25  LEU LEU D . n 
D 1 26  TYR 26  26  26  TYR TYR D . n 
D 1 27  ALA 27  27  27  ALA ALA D . n 
D 1 28  SER 28  28  28  SER SER D . n 
D 1 29  TYR 29  29  29  TYR TYR D . n 
D 1 30  VAL 30  30  30  VAL VAL D . n 
D 1 31  TYR 31  31  31  TYR TYR D . n 
D 1 32  LEU 32  32  32  LEU LEU D . n 
D 1 33  SER 33  33  33  SER SER D . n 
D 1 34  MET 34  34  34  MET MET D . n 
D 1 35  ALA 35  35  35  ALA ALA D . n 
D 1 36  TYR 36  36  36  TYR TYR D . n 
D 1 37  TYR 37  37  37  TYR TYR D . n 
D 1 38  PHE 38  38  38  PHE PHE D . n 
D 1 39  GLU 39  39  39  GLU GLU D . n 
D 1 40  ARG 40  40  40  ARG ARG D . n 
D 1 41  ASP 41  41  41  ASP ASP D . n 
D 1 42  ASP 42  42  42  ASP ASP D . n 
D 1 43  VAL 43  43  43  VAL VAL D . n 
D 1 44  CYS 44  44  44  CYS CYS D . n 
D 1 45  LEU 45  45  45  LEU LEU D . n 
D 1 46  PRO 46  46  46  PRO PRO D . n 
D 1 47  GLY 47  47  47  GLY GLY D . n 
D 1 48  PHE 48  48  48  PHE PHE D . n 
D 1 49  ALA 49  49  49  ALA ALA D . n 
D 1 50  LYS 50  50  50  LYS LYS D . n 
D 1 51  PHE 51  51  51  PHE PHE D . n 
D 1 52  PHE 52  52  52  PHE PHE D . n 
D 1 53  LYS 53  53  53  LYS LYS D . n 
D 1 54  GLU 54  54  54  GLU GLU D . n 
D 1 55  SER 55  55  55  SER SER D . n 
D 1 56  SER 56  56  56  SER SER D . n 
D 1 57  ASP 57  57  57  ASP ASP D . n 
D 1 58  GLU 58  58  58  GLU GLU D . n 
D 1 59  GLU 59  59  59  GLU GLU D . n 
D 1 60  ARG 60  60  60  ARG ARG D . n 
D 1 61  GLU 61  61  61  GLU GLU D . n 
D 1 62  HIS 62  62  62  HIS HIS D . n 
D 1 63  ALA 63  63  63  ALA ALA D . n 
D 1 64  GLN 64  64  64  GLN GLN D . n 
D 1 65  THR 65  65  65  THR THR D . n 
D 1 66  PHE 66  66  66  PHE PHE D . n 
D 1 67  MET 67  67  67  MET MET D . n 
D 1 68  LYS 68  68  68  LYS LYS D . n 
D 1 69  TYR 69  69  69  TYR TYR D . n 
D 1 70  GLN 70  70  70  GLN GLN D . n 
D 1 71  ASN 71  71  71  ASN ASN D . n 
D 1 72  CYS 72  72  72  CYS CYS D . n 
D 1 73  ARG 73  73  73  ARG ARG D . n 
D 1 74  GLY 74  74  74  GLY GLY D . n 
D 1 75  GLY 75  75  75  GLY GLY D . n 
D 1 76  ARG 76  76  76  ARG ARG D . n 
D 1 77  ILE 77  77  77  ILE ILE D . n 
D 1 78  VAL 78  78  78  VAL VAL D . n 
D 1 79  LEU 79  79  79  LEU LEU D . n 
D 1 80  GLN 80  80  80  GLN GLN D . n 
D 1 81  GLN 81  81  81  GLN GLN D . n 
D 1 82  ILE 82  82  82  ILE ILE D . n 
D 1 83  ALA 83  83  83  ALA ALA D . n 
D 1 84  ALA 84  84  84  ALA ALA D . n 
D 1 85  PRO 85  85  85  PRO PRO D . n 
D 1 86  SER 86  86  86  SER SER D . n 
D 1 87  MET 87  87  87  MET MET D . n 
D 1 88  ARG 88  88  88  ARG ARG D . n 
D 1 89  GLU 89  89  89  GLU GLU D . n 
D 1 90  TRP 90  90  90  TRP TRP D . n 
D 1 91  GLY 91  91  91  GLY GLY D . n 
D 1 92  THR 92  92  92  THR THR D . n 
D 1 93  GLY 93  93  93  GLY GLY D . n 
D 1 94  LEU 94  94  94  LEU LEU D . n 
D 1 95  GLU 95  95  95  GLU GLU D . n 
D 1 96  ALA 96  96  96  ALA ALA D . n 
D 1 97  LEU 97  97  97  LEU LEU D . n 
D 1 98  GLN 98  98  98  GLN GLN D . n 
D 1 99  ALA 99  99  99  ALA ALA D . n 
D 1 100 ALA 100 100 100 ALA ALA D . n 
D 1 101 LEU 101 101 101 LEU LEU D . n 
D 1 102 ASP 102 102 102 ASP ASP D . n 
D 1 103 LEU 103 103 103 LEU LEU D . n 
D 1 104 GLU 104 104 104 GLU GLU D . n 
D 1 105 LYS 105 105 105 LYS LYS D . n 
D 1 106 GLN 106 106 106 GLN GLN D . n 
D 1 107 VAL 107 107 107 VAL VAL D . n 
D 1 108 ASN 108 108 108 ASN ASN D . n 
D 1 109 GLN 109 109 109 GLN GLN D . n 
D 1 110 SER 110 110 110 SER SER D . n 
D 1 111 LEU 111 111 111 LEU LEU D . n 
D 1 112 LEU 112 112 112 LEU LEU D . n 
D 1 113 GLU 113 113 113 GLU GLU D . n 
D 1 114 LEU 114 114 114 LEU LEU D . n 
D 1 115 HIS 115 115 115 HIS HIS D . n 
D 1 116 SER 116 116 116 SER SER D . n 
D 1 117 THR 117 117 117 THR THR D . n 
D 1 118 ALA 118 118 118 ALA ALA D . n 
D 1 119 SER 119 119 119 SER SER D . n 
D 1 120 GLY 120 120 120 GLY GLY D . n 
D 1 121 ASN 121 121 121 ASN ASN D . n 
D 1 122 ASN 122 122 122 ASN ASN D . n 
D 1 123 ASP 123 123 123 ASP ASP D . n 
D 1 124 PRO 124 124 124 PRO PRO D . n 
D 1 125 CYS 125 125 125 CYS CYS D . n 
D 1 126 LEU 126 126 126 LEU LEU D . n 
D 1 127 THR 127 127 127 THR THR D . n 
D 1 128 LYS 128 128 128 LYS LYS D . n 
D 1 129 LEU 129 129 129 LEU LEU D . n 
D 1 130 LEU 130 130 130 LEU LEU D . n 
D 1 131 GLU 131 131 131 GLU GLU D . n 
D 1 132 ASP 132 132 132 ASP ASP D . n 
D 1 133 GLU 133 133 133 GLU GLU D . n 
D 1 134 TYR 134 134 134 TYR TYR D . n 
D 1 135 CYS 135 135 135 CYS CYS D . n 
D 1 136 GLU 136 136 136 GLU GLU D . n 
D 1 137 GLU 137 137 137 GLU GLU D . n 
D 1 138 GLN 138 138 138 GLN GLN D . n 
D 1 139 CYS 139 139 139 CYS CYS D . n 
D 1 140 ASP 140 140 140 ASP ASP D . n 
D 1 141 SER 141 141 141 SER SER D . n 
D 1 142 ILE 142 142 142 ILE ILE D . n 
D 1 143 LYS 143 143 143 LYS LYS D . n 
D 1 144 LYS 144 144 144 LYS LYS D . n 
D 1 145 ILE 145 145 145 ILE ILE D . n 
D 1 146 GLY 146 146 146 GLY GLY D . n 
D 1 147 CYS 147 147 147 CYS CYS D . n 
D 1 148 MET 148 148 148 MET MET D . n 
D 1 149 ILE 149 149 149 ILE ILE D . n 
D 1 150 THR 150 150 150 THR THR D . n 
D 1 151 LYS 151 151 151 LYS LYS D . n 
D 1 152 LEU 152 152 152 LEU LEU D . n 
D 1 153 LYS 153 153 153 LYS LYS D . n 
D 1 154 ARG 154 154 154 ARG ARG D . n 
D 1 155 CYS 155 155 155 CYS CYS D . n 
D 1 156 GLY 156 156 156 GLY GLY D . n 
D 1 157 PRO 157 157 157 PRO PRO D . n 
D 1 158 THR 158 158 158 THR THR D . n 
D 1 159 GLY 159 159 159 GLY GLY D . n 
D 1 160 LEU 160 160 160 LEU LEU D . n 
D 1 161 GLY 161 161 161 GLY GLY D . n 
D 1 162 GLU 162 162 162 GLU GLU D . n 
D 1 163 CYS 163 163 163 CYS CYS D . n 
D 1 164 MET 164 164 164 MET MET D . n 
D 1 165 PHE 165 165 165 PHE PHE D . n 
D 1 166 ASP 166 166 166 ASP ASP D . n 
D 1 167 LYS 167 167 167 LYS LYS D . n 
D 1 168 GLU 168 168 168 GLU GLU D . n 
D 1 169 LEU 169 169 169 LEU LEU D . n 
D 1 170 ASN 170 170 170 ASN ASN D . n 
E 1 1   MET 1   1   ?   ?   ?   E . n 
E 1 2   ALA 2   2   2   ALA ALA E . n 
E 1 3   SER 3   3   3   SER SER E . n 
E 1 4   GLN 4   4   4   GLN GLN E . n 
E 1 5   VAL 5   5   5   VAL VAL E . n 
E 1 6   ARG 6   6   6   ARG ARG E . n 
E 1 7   GLN 7   7   7   GLN GLN E . n 
E 1 8   ASN 8   8   8   ASN ASN E . n 
E 1 9   TYR 9   9   9   TYR TYR E . n 
E 1 10  HIS 10  10  10  HIS HIS E . n 
E 1 11  GLU 11  11  11  GLU GLU E . n 
E 1 12  ASP 12  12  12  ASP ASP E . n 
E 1 13  CYS 13  13  13  CYS CYS E . n 
E 1 14  GLU 14  14  14  GLU GLU E . n 
E 1 15  ALA 15  15  15  ALA ALA E . n 
E 1 16  SER 16  16  16  SER SER E . n 
E 1 17  ILE 17  17  17  ILE ILE E . n 
E 1 18  ASN 18  18  18  ASN ASN E . n 
E 1 19  LYS 19  19  19  LYS LYS E . n 
E 1 20  GLN 20  20  20  GLN GLN E . n 
E 1 21  ILE 21  21  21  ILE ILE E . n 
E 1 22  ASN 22  22  22  ASN ASN E . n 
E 1 23  MET 23  23  23  MET MET E . n 
E 1 24  GLU 24  24  24  GLU GLU E . n 
E 1 25  LEU 25  25  25  LEU LEU E . n 
E 1 26  TYR 26  26  26  TYR TYR E . n 
E 1 27  ALA 27  27  27  ALA ALA E . n 
E 1 28  SER 28  28  28  SER SER E . n 
E 1 29  TYR 29  29  29  TYR TYR E . n 
E 1 30  VAL 30  30  30  VAL VAL E . n 
E 1 31  TYR 31  31  31  TYR TYR E . n 
E 1 32  LEU 32  32  32  LEU LEU E . n 
E 1 33  SER 33  33  33  SER SER E . n 
E 1 34  MET 34  34  34  MET MET E . n 
E 1 35  ALA 35  35  35  ALA ALA E . n 
E 1 36  TYR 36  36  36  TYR TYR E . n 
E 1 37  TYR 37  37  37  TYR TYR E . n 
E 1 38  PHE 38  38  38  PHE PHE E . n 
E 1 39  GLU 39  39  39  GLU GLU E . n 
E 1 40  ARG 40  40  40  ARG ARG E . n 
E 1 41  ASP 41  41  41  ASP ASP E . n 
E 1 42  ASP 42  42  42  ASP ASP E . n 
E 1 43  VAL 43  43  43  VAL VAL E . n 
E 1 44  CYS 44  44  44  CYS CYS E . n 
E 1 45  LEU 45  45  45  LEU LEU E . n 
E 1 46  PRO 46  46  46  PRO PRO E . n 
E 1 47  GLY 47  47  47  GLY GLY E . n 
E 1 48  PHE 48  48  48  PHE PHE E . n 
E 1 49  ALA 49  49  49  ALA ALA E . n 
E 1 50  LYS 50  50  50  LYS LYS E . n 
E 1 51  PHE 51  51  51  PHE PHE E . n 
E 1 52  PHE 52  52  52  PHE PHE E . n 
E 1 53  LYS 53  53  53  LYS LYS E . n 
E 1 54  GLU 54  54  54  GLU GLU E . n 
E 1 55  SER 55  55  55  SER SER E . n 
E 1 56  SER 56  56  56  SER SER E . n 
E 1 57  ASP 57  57  57  ASP ASP E . n 
E 1 58  GLU 58  58  58  GLU GLU E . n 
E 1 59  GLU 59  59  59  GLU GLU E . n 
E 1 60  ARG 60  60  60  ARG ARG E . n 
E 1 61  GLU 61  61  61  GLU GLU E . n 
E 1 62  HIS 62  62  62  HIS HIS E . n 
E 1 63  ALA 63  63  63  ALA ALA E . n 
E 1 64  GLN 64  64  64  GLN GLN E . n 
E 1 65  THR 65  65  65  THR THR E . n 
E 1 66  PHE 66  66  66  PHE PHE E . n 
E 1 67  MET 67  67  67  MET MET E . n 
E 1 68  LYS 68  68  68  LYS LYS E . n 
E 1 69  TYR 69  69  69  TYR TYR E . n 
E 1 70  GLN 70  70  70  GLN GLN E . n 
E 1 71  ASN 71  71  71  ASN ASN E . n 
E 1 72  CYS 72  72  72  CYS CYS E . n 
E 1 73  ARG 73  73  73  ARG ARG E . n 
E 1 74  GLY 74  74  74  GLY GLY E . n 
E 1 75  GLY 75  75  75  GLY GLY E . n 
E 1 76  ARG 76  76  76  ARG ARG E . n 
E 1 77  ILE 77  77  77  ILE ILE E . n 
E 1 78  VAL 78  78  78  VAL VAL E . n 
E 1 79  LEU 79  79  79  LEU LEU E . n 
E 1 80  GLN 80  80  80  GLN GLN E . n 
E 1 81  GLN 81  81  81  GLN GLN E . n 
E 1 82  ILE 82  82  82  ILE ILE E . n 
E 1 83  ALA 83  83  83  ALA ALA E . n 
E 1 84  ALA 84  84  84  ALA ALA E . n 
E 1 85  PRO 85  85  85  PRO PRO E . n 
E 1 86  SER 86  86  86  SER SER E . n 
E 1 87  MET 87  87  87  MET MET E . n 
E 1 88  ARG 88  88  88  ARG ARG E . n 
E 1 89  GLU 89  89  89  GLU GLU E . n 
E 1 90  TRP 90  90  90  TRP TRP E . n 
E 1 91  GLY 91  91  91  GLY GLY E . n 
E 1 92  THR 92  92  92  THR THR E . n 
E 1 93  GLY 93  93  93  GLY GLY E . n 
E 1 94  LEU 94  94  94  LEU LEU E . n 
E 1 95  GLU 95  95  95  GLU GLU E . n 
E 1 96  ALA 96  96  96  ALA ALA E . n 
E 1 97  LEU 97  97  97  LEU LEU E . n 
E 1 98  GLN 98  98  98  GLN GLN E . n 
E 1 99  ALA 99  99  99  ALA ALA E . n 
E 1 100 ALA 100 100 100 ALA ALA E . n 
E 1 101 LEU 101 101 101 LEU LEU E . n 
E 1 102 ASP 102 102 102 ASP ASP E . n 
E 1 103 LEU 103 103 103 LEU LEU E . n 
E 1 104 GLU 104 104 104 GLU GLU E . n 
E 1 105 LYS 105 105 105 LYS LYS E . n 
E 1 106 GLN 106 106 106 GLN GLN E . n 
E 1 107 VAL 107 107 107 VAL VAL E . n 
E 1 108 ASN 108 108 108 ASN ASN E . n 
E 1 109 GLN 109 109 109 GLN GLN E . n 
E 1 110 SER 110 110 110 SER SER E . n 
E 1 111 LEU 111 111 111 LEU LEU E . n 
E 1 112 LEU 112 112 112 LEU LEU E . n 
E 1 113 GLU 113 113 113 GLU GLU E . n 
E 1 114 LEU 114 114 114 LEU LEU E . n 
E 1 115 HIS 115 115 115 HIS HIS E . n 
E 1 116 SER 116 116 116 SER SER E . n 
E 1 117 THR 117 117 117 THR THR E . n 
E 1 118 ALA 118 118 118 ALA ALA E . n 
E 1 119 SER 119 119 119 SER SER E . n 
E 1 120 GLY 120 120 120 GLY GLY E . n 
E 1 121 ASN 121 121 121 ASN ASN E . n 
E 1 122 ASN 122 122 122 ASN ASN E . n 
E 1 123 ASP 123 123 123 ASP ASP E . n 
E 1 124 PRO 124 124 124 PRO PRO E . n 
E 1 125 CYS 125 125 125 CYS CYS E . n 
E 1 126 LEU 126 126 126 LEU LEU E . n 
E 1 127 THR 127 127 127 THR THR E . n 
E 1 128 LYS 128 128 128 LYS LYS E . n 
E 1 129 LEU 129 129 129 LEU LEU E . n 
E 1 130 LEU 130 130 130 LEU LEU E . n 
E 1 131 GLU 131 131 131 GLU GLU E . n 
E 1 132 ASP 132 132 132 ASP ASP E . n 
E 1 133 GLU 133 133 133 GLU GLU E . n 
E 1 134 TYR 134 134 134 TYR TYR E . n 
E 1 135 CYS 135 135 135 CYS CYS E . n 
E 1 136 GLU 136 136 136 GLU GLU E . n 
E 1 137 GLU 137 137 137 GLU GLU E . n 
E 1 138 GLN 138 138 138 GLN GLN E . n 
E 1 139 CYS 139 139 139 CYS CYS E . n 
E 1 140 ASP 140 140 140 ASP ASP E . n 
E 1 141 SER 141 141 141 SER SER E . n 
E 1 142 ILE 142 142 142 ILE ILE E . n 
E 1 143 LYS 143 143 143 LYS LYS E . n 
E 1 144 LYS 144 144 144 LYS LYS E . n 
E 1 145 ILE 145 145 145 ILE ILE E . n 
E 1 146 GLY 146 146 146 GLY GLY E . n 
E 1 147 CYS 147 147 147 CYS CYS E . n 
E 1 148 MET 148 148 148 MET MET E . n 
E 1 149 ILE 149 149 149 ILE ILE E . n 
E 1 150 THR 150 150 150 THR THR E . n 
E 1 151 LYS 151 151 151 LYS LYS E . n 
E 1 152 LEU 152 152 152 LEU LEU E . n 
E 1 153 LYS 153 153 153 LYS LYS E . n 
E 1 154 ARG 154 154 154 ARG ARG E . n 
E 1 155 CYS 155 155 155 CYS CYS E . n 
E 1 156 GLY 156 156 156 GLY GLY E . n 
E 1 157 PRO 157 157 157 PRO PRO E . n 
E 1 158 THR 158 158 158 THR THR E . n 
E 1 159 GLY 159 159 159 GLY GLY E . n 
E 1 160 LEU 160 160 160 LEU LEU E . n 
E 1 161 GLY 161 161 161 GLY GLY E . n 
E 1 162 GLU 162 162 162 GLU GLU E . n 
E 1 163 CYS 163 163 163 CYS CYS E . n 
E 1 164 MET 164 164 164 MET MET E . n 
E 1 165 PHE 165 165 165 PHE PHE E . n 
E 1 166 ASP 166 166 166 ASP ASP E . n 
E 1 167 LYS 167 167 167 LYS LYS E . n 
E 1 168 GLU 168 168 168 GLU GLU E . n 
E 1 169 LEU 169 169 169 LEU LEU E . n 
E 1 170 ASN 170 170 170 ASN ASN E . n 
F 1 1   MET 1   1   ?   ?   ?   F . n 
F 1 2   ALA 2   2   ?   ?   ?   F . n 
F 1 3   SER 3   3   ?   ?   ?   F . n 
F 1 4   GLN 4   4   ?   ?   ?   F . n 
F 1 5   VAL 5   5   ?   ?   ?   F . n 
F 1 6   ARG 6   6   ?   ?   ?   F . n 
F 1 7   GLN 7   7   ?   ?   ?   F . n 
F 1 8   ASN 8   8   ?   ?   ?   F . n 
F 1 9   TYR 9   9   9   TYR TYR F . n 
F 1 10  HIS 10  10  10  HIS HIS F . n 
F 1 11  GLU 11  11  11  GLU GLU F . n 
F 1 12  ASP 12  12  12  ASP ASP F . n 
F 1 13  CYS 13  13  13  CYS CYS F . n 
F 1 14  GLU 14  14  14  GLU GLU F . n 
F 1 15  ALA 15  15  15  ALA ALA F . n 
F 1 16  SER 16  16  16  SER SER F . n 
F 1 17  ILE 17  17  17  ILE ILE F . n 
F 1 18  ASN 18  18  18  ASN ASN F . n 
F 1 19  LYS 19  19  19  LYS LYS F . n 
F 1 20  GLN 20  20  20  GLN GLN F . n 
F 1 21  ILE 21  21  21  ILE ILE F . n 
F 1 22  ASN 22  22  22  ASN ASN F . n 
F 1 23  MET 23  23  23  MET MET F . n 
F 1 24  GLU 24  24  24  GLU GLU F . n 
F 1 25  LEU 25  25  25  LEU LEU F . n 
F 1 26  TYR 26  26  26  TYR TYR F . n 
F 1 27  ALA 27  27  27  ALA ALA F . n 
F 1 28  SER 28  28  28  SER SER F . n 
F 1 29  TYR 29  29  29  TYR TYR F . n 
F 1 30  VAL 30  30  30  VAL VAL F . n 
F 1 31  TYR 31  31  31  TYR TYR F . n 
F 1 32  LEU 32  32  32  LEU LEU F . n 
F 1 33  SER 33  33  33  SER SER F . n 
F 1 34  MET 34  34  34  MET MET F . n 
F 1 35  ALA 35  35  35  ALA ALA F . n 
F 1 36  TYR 36  36  36  TYR TYR F . n 
F 1 37  TYR 37  37  37  TYR TYR F . n 
F 1 38  PHE 38  38  38  PHE PHE F . n 
F 1 39  GLU 39  39  39  GLU GLU F . n 
F 1 40  ARG 40  40  40  ARG ARG F . n 
F 1 41  ASP 41  41  41  ASP ASP F . n 
F 1 42  ASP 42  42  42  ASP ASP F . n 
F 1 43  VAL 43  43  43  VAL VAL F . n 
F 1 44  CYS 44  44  44  CYS CYS F . n 
F 1 45  LEU 45  45  45  LEU LEU F . n 
F 1 46  PRO 46  46  46  PRO PRO F . n 
F 1 47  GLY 47  47  47  GLY GLY F . n 
F 1 48  PHE 48  48  48  PHE PHE F . n 
F 1 49  ALA 49  49  49  ALA ALA F . n 
F 1 50  LYS 50  50  50  LYS LYS F . n 
F 1 51  PHE 51  51  51  PHE PHE F . n 
F 1 52  PHE 52  52  52  PHE PHE F . n 
F 1 53  LYS 53  53  53  LYS LYS F . n 
F 1 54  GLU 54  54  54  GLU GLU F . n 
F 1 55  SER 55  55  55  SER SER F . n 
F 1 56  SER 56  56  56  SER SER F . n 
F 1 57  ASP 57  57  57  ASP ASP F . n 
F 1 58  GLU 58  58  58  GLU GLU F . n 
F 1 59  GLU 59  59  59  GLU GLU F . n 
F 1 60  ARG 60  60  60  ARG ARG F . n 
F 1 61  GLU 61  61  61  GLU GLU F . n 
F 1 62  HIS 62  62  62  HIS HIS F . n 
F 1 63  ALA 63  63  63  ALA ALA F . n 
F 1 64  GLN 64  64  64  GLN GLN F . n 
F 1 65  THR 65  65  65  THR THR F . n 
F 1 66  PHE 66  66  66  PHE PHE F . n 
F 1 67  MET 67  67  67  MET MET F . n 
F 1 68  LYS 68  68  68  LYS LYS F . n 
F 1 69  TYR 69  69  69  TYR TYR F . n 
F 1 70  GLN 70  70  70  GLN GLN F . n 
F 1 71  ASN 71  71  71  ASN ASN F . n 
F 1 72  CYS 72  72  72  CYS CYS F . n 
F 1 73  ARG 73  73  73  ARG ARG F . n 
F 1 74  GLY 74  74  74  GLY GLY F . n 
F 1 75  GLY 75  75  75  GLY GLY F . n 
F 1 76  ARG 76  76  76  ARG ARG F . n 
F 1 77  ILE 77  77  77  ILE ILE F . n 
F 1 78  VAL 78  78  78  VAL VAL F . n 
F 1 79  LEU 79  79  79  LEU LEU F . n 
F 1 80  GLN 80  80  80  GLN GLN F . n 
F 1 81  GLN 81  81  81  GLN GLN F . n 
F 1 82  ILE 82  82  82  ILE ILE F . n 
F 1 83  ALA 83  83  83  ALA ALA F . n 
F 1 84  ALA 84  84  84  ALA ALA F . n 
F 1 85  PRO 85  85  85  PRO PRO F . n 
F 1 86  SER 86  86  86  SER SER F . n 
F 1 87  MET 87  87  87  MET MET F . n 
F 1 88  ARG 88  88  88  ARG ARG F . n 
F 1 89  GLU 89  89  89  GLU GLU F . n 
F 1 90  TRP 90  90  90  TRP TRP F . n 
F 1 91  GLY 91  91  91  GLY GLY F . n 
F 1 92  THR 92  92  92  THR THR F . n 
F 1 93  GLY 93  93  93  GLY GLY F . n 
F 1 94  LEU 94  94  94  LEU LEU F . n 
F 1 95  GLU 95  95  95  GLU GLU F . n 
F 1 96  ALA 96  96  96  ALA ALA F . n 
F 1 97  LEU 97  97  97  LEU LEU F . n 
F 1 98  GLN 98  98  98  GLN GLN F . n 
F 1 99  ALA 99  99  99  ALA ALA F . n 
F 1 100 ALA 100 100 100 ALA ALA F . n 
F 1 101 LEU 101 101 101 LEU LEU F . n 
F 1 102 ASP 102 102 102 ASP ASP F . n 
F 1 103 LEU 103 103 103 LEU LEU F . n 
F 1 104 GLU 104 104 104 GLU GLU F . n 
F 1 105 LYS 105 105 105 LYS LYS F . n 
F 1 106 GLN 106 106 106 GLN GLN F . n 
F 1 107 VAL 107 107 107 VAL VAL F . n 
F 1 108 ASN 108 108 108 ASN ASN F . n 
F 1 109 GLN 109 109 109 GLN GLN F . n 
F 1 110 SER 110 110 110 SER SER F . n 
F 1 111 LEU 111 111 111 LEU LEU F . n 
F 1 112 LEU 112 112 112 LEU LEU F . n 
F 1 113 GLU 113 113 113 GLU GLU F . n 
F 1 114 LEU 114 114 114 LEU LEU F . n 
F 1 115 HIS 115 115 115 HIS HIS F . n 
F 1 116 SER 116 116 116 SER SER F . n 
F 1 117 THR 117 117 117 THR THR F . n 
F 1 118 ALA 118 118 118 ALA ALA F . n 
F 1 119 SER 119 119 119 SER SER F . n 
F 1 120 GLY 120 120 120 GLY GLY F . n 
F 1 121 ASN 121 121 121 ASN ASN F . n 
F 1 122 ASN 122 122 122 ASN ASN F . n 
F 1 123 ASP 123 123 123 ASP ASP F . n 
F 1 124 PRO 124 124 124 PRO PRO F . n 
F 1 125 CYS 125 125 125 CYS CYS F . n 
F 1 126 LEU 126 126 126 LEU LEU F . n 
F 1 127 THR 127 127 127 THR THR F . n 
F 1 128 LYS 128 128 128 LYS LYS F . n 
F 1 129 LEU 129 129 129 LEU LEU F . n 
F 1 130 LEU 130 130 130 LEU LEU F . n 
F 1 131 GLU 131 131 131 GLU GLU F . n 
F 1 132 ASP 132 132 132 ASP ASP F . n 
F 1 133 GLU 133 133 133 GLU GLU F . n 
F 1 134 TYR 134 134 134 TYR TYR F . n 
F 1 135 CYS 135 135 135 CYS CYS F . n 
F 1 136 GLU 136 136 136 GLU GLU F . n 
F 1 137 GLU 137 137 137 GLU GLU F . n 
F 1 138 GLN 138 138 138 GLN GLN F . n 
F 1 139 CYS 139 139 139 CYS CYS F . n 
F 1 140 ASP 140 140 140 ASP ASP F . n 
F 1 141 SER 141 141 141 SER SER F . n 
F 1 142 ILE 142 142 142 ILE ILE F . n 
F 1 143 LYS 143 143 143 LYS LYS F . n 
F 1 144 LYS 144 144 144 LYS LYS F . n 
F 1 145 ILE 145 145 145 ILE ILE F . n 
F 1 146 GLY 146 146 146 GLY GLY F . n 
F 1 147 CYS 147 147 147 CYS CYS F . n 
F 1 148 MET 148 148 148 MET MET F . n 
F 1 149 ILE 149 149 149 ILE ILE F . n 
F 1 150 THR 150 150 150 THR THR F . n 
F 1 151 LYS 151 151 151 LYS LYS F . n 
F 1 152 LEU 152 152 152 LEU LEU F . n 
F 1 153 LYS 153 153 153 LYS LYS F . n 
F 1 154 ARG 154 154 154 ARG ARG F . n 
F 1 155 CYS 155 155 155 CYS CYS F . n 
F 1 156 GLY 156 156 156 GLY GLY F . n 
F 1 157 PRO 157 157 157 PRO PRO F . n 
F 1 158 THR 158 158 158 THR THR F . n 
F 1 159 GLY 159 159 159 GLY GLY F . n 
F 1 160 LEU 160 160 160 LEU LEU F . n 
F 1 161 GLY 161 161 161 GLY GLY F . n 
F 1 162 GLU 162 162 162 GLU GLU F . n 
F 1 163 CYS 163 163 163 CYS CYS F . n 
F 1 164 MET 164 164 164 MET MET F . n 
F 1 165 PHE 165 165 165 PHE PHE F . n 
F 1 166 ASP 166 166 166 ASP ASP F . n 
F 1 167 LYS 167 167 167 LYS LYS F . n 
F 1 168 GLU 168 168 168 GLU GLU F . n 
F 1 169 LEU 169 169 169 LEU LEU F . n 
F 1 170 ASN 170 170 170 ASN ASN F . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 2 FE  1  201 1   FE  FE  B . 
H 2 FE  1  202 9   FE  FE  B . 
I 2 FE  1  201 3   FE  FE  A . 
J 2 FE  1  201 7   FE  FE  C . 
K 2 FE  1  201 2   FE  FE  D . 
L 2 FE  1  202 4   FE  FE  D . 
M 2 FE  1  201 5   FE  FE  E . 
N 2 FE  1  202 8   FE  FE  E . 
O 2 FE  1  201 6   FE  FE  F . 
P 2 FE  1  202 10  FE  FE  F . 
Q 3 HOH 1  301 70  HOH HOH B . 
Q 3 HOH 2  302 201 HOH HOH B . 
Q 3 HOH 3  303 59  HOH HOH B . 
Q 3 HOH 4  304 9   HOH HOH B . 
Q 3 HOH 5  305 24  HOH HOH B . 
Q 3 HOH 6  306 54  HOH HOH B . 
Q 3 HOH 7  307 63  HOH HOH B . 
Q 3 HOH 8  308 34  HOH HOH B . 
Q 3 HOH 9  309 53  HOH HOH B . 
Q 3 HOH 10 310 64  HOH HOH B . 
R 3 HOH 1  301 68  HOH HOH A . 
R 3 HOH 2  302 51  HOH HOH A . 
R 3 HOH 3  303 35  HOH HOH A . 
R 3 HOH 4  304 45  HOH HOH A . 
R 3 HOH 5  305 47  HOH HOH A . 
R 3 HOH 6  306 60  HOH HOH A . 
R 3 HOH 7  307 2   HOH HOH A . 
R 3 HOH 8  308 14  HOH HOH A . 
R 3 HOH 9  309 44  HOH HOH A . 
R 3 HOH 10 310 39  HOH HOH A . 
R 3 HOH 11 311 67  HOH HOH A . 
R 3 HOH 12 312 55  HOH HOH A . 
S 3 HOH 1  301 41  HOH HOH C . 
S 3 HOH 2  302 57  HOH HOH C . 
S 3 HOH 3  303 27  HOH HOH C . 
S 3 HOH 4  304 66  HOH HOH C . 
S 3 HOH 5  305 37  HOH HOH C . 
S 3 HOH 6  306 7   HOH HOH C . 
S 3 HOH 7  307 65  HOH HOH C . 
S 3 HOH 8  308 56  HOH HOH C . 
S 3 HOH 9  309 28  HOH HOH C . 
S 3 HOH 10 310 22  HOH HOH C . 
T 3 HOH 1  301 1   HOH HOH D . 
T 3 HOH 2  302 40  HOH HOH D . 
T 3 HOH 3  303 8   HOH HOH D . 
T 3 HOH 4  304 18  HOH HOH D . 
T 3 HOH 5  305 6   HOH HOH D . 
T 3 HOH 6  306 73  HOH HOH D . 
T 3 HOH 7  307 62  HOH HOH D . 
T 3 HOH 8  308 48  HOH HOH D . 
U 3 HOH 1  301 71  HOH HOH E . 
U 3 HOH 2  302 61  HOH HOH E . 
U 3 HOH 3  303 72  HOH HOH E . 
U 3 HOH 4  304 43  HOH HOH E . 
U 3 HOH 5  305 21  HOH HOH E . 
U 3 HOH 6  306 3   HOH HOH E . 
U 3 HOH 7  307 4   HOH HOH E . 
U 3 HOH 8  308 42  HOH HOH E . 
U 3 HOH 9  309 20  HOH HOH E . 
U 3 HOH 10 310 49  HOH HOH E . 
U 3 HOH 11 311 26  HOH HOH E . 
V 3 HOH 1  301 52  HOH HOH F . 
V 3 HOH 2  302 17  HOH HOH F . 
V 3 HOH 3  303 29  HOH HOH F . 
V 3 HOH 4  304 50  HOH HOH F . 
V 3 HOH 5  305 31  HOH HOH F . 
V 3 HOH 6  306 46  HOH HOH F . 
V 3 HOH 7  307 58  HOH HOH F . 
V 3 HOH 8  308 23  HOH HOH F . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? '(1.14_3260: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .                  2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .                  3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? .                  4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8YKR 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     125.080 
_cell.length_a_esd                 ? 
_cell.length_b                     125.080 
_cell.length_b_esd                 ? 
_cell.length_c                     175.917 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        48 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8YKR 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                79 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'I 4' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8YKR 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.95 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          58.29 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'sodium phosphate monobasic monohydrate, potassium phosphate dibasic' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-11-27 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.978 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL18U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.978 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL18U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8YKR 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.50 
_reflns.d_resolution_low                               30.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     46591 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          4.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.596 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.112 
_reflns.pdbx_Rpim_I_all                                0.043 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       314666 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.993 
_reflns.pdbx_CC_star                                   0.998 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.104 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
2.50 2.54  ? ? ? ? ? ? 2327 ? ? ? ? ? ? ? ? ? ? ? 6.8 0.440 ? ? 0.868 0.332 ? 1  1 0.746 0.924 ? 100.0 ? 0.801 ? ? ? ? ? ? ? ? ? 
2.54 2.59  ? ? ? ? ? ? 2293 ? ? ? ? ? ? ? ? ? ? ? 6.7 0.449 ? ? 0.744 0.287 ? 2  1 0.786 0.938 ? 100.0 ? 0.686 ? ? ? ? ? ? ? ? ? 
2.59 2.64  ? ? ? ? ? ? 2353 ? ? ? ? ? ? ? ? ? ? ? 6.5 0.440 ? ? 0.647 0.254 ? 3  1 0.821 0.949 ? 100.0 ? 0.595 ? ? ? ? ? ? ? ? ? 
2.64 2.69  ? ? ? ? ? ? 2279 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.457 ? ? 0.532 0.202 ? 4  1 0.891 0.971 ? 100.0 ? 0.492 ? ? ? ? ? ? ? ? ? 
2.69 2.75  ? ? ? ? ? ? 2343 ? ? ? ? ? ? ? ? ? ? ? 7.0 0.473 ? ? 0.502 0.189 ? 5  1 0.898 0.973 ? 100.0 ? 0.464 ? ? ? ? ? ? ? ? ? 
2.75 2.82  ? ? ? ? ? ? 2322 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.485 ? ? 0.428 0.162 ? 6  1 0.926 0.981 ? 100.0 ? 0.396 ? ? ? ? ? ? ? ? ? 
2.82 2.89  ? ? ? ? ? ? 2329 ? ? ? ? ? ? ? ? ? ? ? 6.8 0.509 ? ? 0.359 0.137 ? 7  1 0.939 0.984 ? 100.0 ? 0.332 ? ? ? ? ? ? ? ? ? 
2.89 2.96  ? ? ? ? ? ? 2337 ? ? ? ? ? ? ? ? ? ? ? 6.7 0.515 ? ? 0.329 0.127 ? 8  1 0.946 0.986 ? 100.0 ? 0.303 ? ? ? ? ? ? ? ? ? 
2.96 3.05  ? ? ? ? ? ? 2333 ? ? ? ? ? ? ? ? ? ? ? 6.3 0.550 ? ? 0.276 0.109 ? 9  1 0.959 0.990 ? 100.0 ? 0.253 ? ? ? ? ? ? ? ? ? 
3.05 3.15  ? ? ? ? ? ? 2313 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.575 ? ? 0.222 0.085 ? 10 1 0.974 0.993 ? 100.0 ? 0.205 ? ? ? ? ? ? ? ? ? 
3.15 3.26  ? ? ? ? ? ? 2302 ? ? ? ? ? ? ? ? ? ? ? 6.5 0.596 ? ? 0.186 0.073 ? 11 1 0.982 0.996 ? 100.0 ? 0.171 ? ? ? ? ? ? ? ? ? 
3.26 3.39  ? ? ? ? ? ? 2336 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.642 ? ? 0.153 0.058 ? 12 1 0.986 0.996 ? 100.0 ? 0.142 ? ? ? ? ? ? ? ? ? 
3.39 3.55  ? ? ? ? ? ? 2349 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.695 ? ? 0.119 0.045 ? 13 1 0.991 0.998 ? 100.0 ? 0.110 ? ? ? ? ? ? ? ? ? 
3.55 3.73  ? ? ? ? ? ? 2309 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.783 ? ? 0.104 0.040 ? 14 1 0.993 0.998 ? 100.0 ? 0.096 ? ? ? ? ? ? ? ? ? 
3.73 3.97  ? ? ? ? ? ? 2307 ? ? ? ? ? ? ? ? ? ? ? 6.5 0.819 ? ? 0.086 0.034 ? 15 1 0.995 0.999 ? 100.0 ? 0.080 ? ? ? ? ? ? ? ? ? 
3.97 4.27  ? ? ? ? ? ? 2362 ? ? ? ? ? ? ? ? ? ? ? 6.8 0.833 ? ? 0.072 0.028 ? 16 1 0.997 0.999 ? 100.0 ? 0.067 ? ? ? ? ? ? ? ? ? 
4.27 4.70  ? ? ? ? ? ? 2332 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.850 ? ? 0.063 0.024 ? 17 1 0.997 0.999 ? 100.0 ? 0.058 ? ? ? ? ? ? ? ? ? 
4.70 5.38  ? ? ? ? ? ? 2336 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.746 ? ? 0.058 0.022 ? 18 1 0.998 0.999 ? 100.0 ? 0.053 ? ? ? ? ? ? ? ? ? 
5.38 6.76  ? ? ? ? ? ? 2345 ? ? ? ? ? ? ? ? ? ? ? 6.5 0.588 ? ? 0.059 0.023 ? 19 1 0.997 0.999 ? 100.0 ? 0.054 ? ? ? ? ? ? ? ? ? 
6.76 30.00 ? ? ? ? ? ? 2384 ? ? ? ? ? ? ? ? ? ? ? 6.6 0.448 ? ? 0.033 0.013 ? 20 1 0.999 1.000 ? 99.9  ? 0.031 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8YKR 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.500 
_refine.ls_d_res_low                             29.482 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     46566 
_refine.ls_number_reflns_R_free                  2000 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.94 
_refine.ls_percent_reflns_R_free                 4.29 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1873 
_refine.ls_R_factor_R_free                       0.2302 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1854 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.36 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 24.64 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.31 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        8010 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         10 
_refine_hist.number_atoms_solvent             59 
_refine_hist.number_atoms_total               8079 
_refine_hist.d_res_high                       2.500 
_refine_hist.d_res_low                        29.482 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010 ? 8174  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.139 ? 10999 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 8.570 ? 7039  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.050 ? 1161  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.006 ? 1458  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.5    2.5621 . . 144 3151 100.00 . . . . 0.2487 . . . . . . . . . . . 0.3339 
'X-RAY DIFFRACTION' 2.5621 2.6314 . . 134 3175 100.00 . . . . 0.2273 . . . . . . . . . . . 0.3061 
'X-RAY DIFFRACTION' 2.6314 2.7087 . . 156 3187 100.00 . . . . 0.2122 . . . . . . . . . . . 0.2647 
'X-RAY DIFFRACTION' 2.7087 2.7961 . . 139 3152 100.00 . . . . 0.2231 . . . . . . . . . . . 0.2876 
'X-RAY DIFFRACTION' 2.7961 2.8960 . . 137 3204 100.00 . . . . 0.2259 . . . . . . . . . . . 0.2966 
'X-RAY DIFFRACTION' 2.8960 3.0118 . . 146 3138 100.00 . . . . 0.2315 . . . . . . . . . . . 0.2907 
'X-RAY DIFFRACTION' 3.0118 3.1487 . . 154 3191 100.00 . . . . 0.2257 . . . . . . . . . . . 0.2749 
'X-RAY DIFFRACTION' 3.1487 3.3145 . . 132 3185 100.00 . . . . 0.2226 . . . . . . . . . . . 0.3051 
'X-RAY DIFFRACTION' 3.3145 3.5219 . . 142 3174 100.00 . . . . 0.2025 . . . . . . . . . . . 0.2342 
'X-RAY DIFFRACTION' 3.5219 3.7933 . . 140 3220 100.00 . . . . 0.1793 . . . . . . . . . . . 0.2184 
'X-RAY DIFFRACTION' 3.7933 4.1741 . . 139 3199 100.00 . . . . 0.1632 . . . . . . . . . . . 0.2227 
'X-RAY DIFFRACTION' 4.1741 4.7758 . . 151 3167 100.00 . . . . 0.1430 . . . . . . . . . . . 0.1675 
'X-RAY DIFFRACTION' 4.7758 6.0087 . . 145 3209 100.00 . . . . 0.1748 . . . . . . . . . . . 0.2188 
'X-RAY DIFFRACTION' 6.0087 29.482 . . 141 3214 99.00  . . . . 0.1511 . . . . . . . . . . . 0.1710 
# 
_struct.entry_id                     8YKR 
_struct.title                        
'Enhancing the Gastric Stability of Ferritin Nanocage via Computational-Assisted Disulfide Bond Engineering' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8YKR 
_struct_keywords.text            'Ferritin, Disulfide Bond, Computational-Assisted, BIOSYNTHETIC PROTEIN' 
_struct_keywords.pdbx_keywords   'BIOSYNTHETIC PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 2 ? 
K N N 2 ? 
L N N 2 ? 
M N N 2 ? 
N N N 2 ? 
O N N 2 ? 
P N N 2 ? 
Q N N 3 ? 
R N N 3 ? 
S N N 3 ? 
T N N 3 ? 
U N N 3 ? 
V N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    T2B7E1_PENJP 
_struct_ref.pdbx_db_accession          T2B7E1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MASQVRQNYHEDCEASINKQINMELYASYVYLSMAYYFERDDVALPGFAKFFKESSDEEREHAQTFMKYQNKRGGRIVLQ
QIAAPSMQEWGTGLEALQAALDLEKQVNQSLLELHSTASGNNDPHLTKLLEDEYLEEQVDSIKKIGDMITKLKRAGPTGL
GEYMFDKELN
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8YKR B 1 ? 170 ? T2B7E1 1 ? 170 ? 1 170 
2 1 8YKR A 1 ? 170 ? T2B7E1 1 ? 170 ? 1 170 
3 1 8YKR C 1 ? 170 ? T2B7E1 1 ? 170 ? 1 170 
4 1 8YKR D 1 ? 170 ? T2B7E1 1 ? 170 ? 1 170 
5 1 8YKR E 1 ? 170 ? T2B7E1 1 ? 170 ? 1 170 
6 1 8YKR F 1 ? 170 ? T2B7E1 1 ? 170 ? 1 170 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8YKR CYS B 44  ? UNP T2B7E1 ALA 44  'engineered mutation' 44  1  
1 8YKR CYS B 72  ? UNP T2B7E1 LYS 72  'engineered mutation' 72  2  
1 8YKR ARG B 88  ? UNP T2B7E1 GLN 88  conflict              88  3  
1 8YKR CYS B 125 ? UNP T2B7E1 HIS 125 'engineered mutation' 125 4  
1 8YKR CYS B 135 ? UNP T2B7E1 LEU 135 'engineered mutation' 135 5  
1 8YKR CYS B 139 ? UNP T2B7E1 VAL 139 'engineered mutation' 139 6  
1 8YKR CYS B 147 ? UNP T2B7E1 ASP 147 'engineered mutation' 147 7  
1 8YKR CYS B 155 ? UNP T2B7E1 ALA 155 'engineered mutation' 155 8  
1 8YKR CYS B 163 ? UNP T2B7E1 TYR 163 'engineered mutation' 163 9  
2 8YKR CYS A 44  ? UNP T2B7E1 ALA 44  'engineered mutation' 44  10 
2 8YKR CYS A 72  ? UNP T2B7E1 LYS 72  'engineered mutation' 72  11 
2 8YKR ARG A 88  ? UNP T2B7E1 GLN 88  conflict              88  12 
2 8YKR CYS A 125 ? UNP T2B7E1 HIS 125 'engineered mutation' 125 13 
2 8YKR CYS A 135 ? UNP T2B7E1 LEU 135 'engineered mutation' 135 14 
2 8YKR CYS A 139 ? UNP T2B7E1 VAL 139 'engineered mutation' 139 15 
2 8YKR CYS A 147 ? UNP T2B7E1 ASP 147 'engineered mutation' 147 16 
2 8YKR CYS A 155 ? UNP T2B7E1 ALA 155 'engineered mutation' 155 17 
2 8YKR CYS A 163 ? UNP T2B7E1 TYR 163 'engineered mutation' 163 18 
3 8YKR CYS C 44  ? UNP T2B7E1 ALA 44  'engineered mutation' 44  19 
3 8YKR CYS C 72  ? UNP T2B7E1 LYS 72  'engineered mutation' 72  20 
3 8YKR ARG C 88  ? UNP T2B7E1 GLN 88  conflict              88  21 
3 8YKR CYS C 125 ? UNP T2B7E1 HIS 125 'engineered mutation' 125 22 
3 8YKR CYS C 135 ? UNP T2B7E1 LEU 135 'engineered mutation' 135 23 
3 8YKR CYS C 139 ? UNP T2B7E1 VAL 139 'engineered mutation' 139 24 
3 8YKR CYS C 147 ? UNP T2B7E1 ASP 147 'engineered mutation' 147 25 
3 8YKR CYS C 155 ? UNP T2B7E1 ALA 155 'engineered mutation' 155 26 
3 8YKR CYS C 163 ? UNP T2B7E1 TYR 163 'engineered mutation' 163 27 
4 8YKR CYS D 44  ? UNP T2B7E1 ALA 44  'engineered mutation' 44  28 
4 8YKR CYS D 72  ? UNP T2B7E1 LYS 72  'engineered mutation' 72  29 
4 8YKR ARG D 88  ? UNP T2B7E1 GLN 88  conflict              88  30 
4 8YKR CYS D 125 ? UNP T2B7E1 HIS 125 'engineered mutation' 125 31 
4 8YKR CYS D 135 ? UNP T2B7E1 LEU 135 'engineered mutation' 135 32 
4 8YKR CYS D 139 ? UNP T2B7E1 VAL 139 'engineered mutation' 139 33 
4 8YKR CYS D 147 ? UNP T2B7E1 ASP 147 'engineered mutation' 147 34 
4 8YKR CYS D 155 ? UNP T2B7E1 ALA 155 'engineered mutation' 155 35 
4 8YKR CYS D 163 ? UNP T2B7E1 TYR 163 'engineered mutation' 163 36 
5 8YKR CYS E 44  ? UNP T2B7E1 ALA 44  'engineered mutation' 44  37 
5 8YKR CYS E 72  ? UNP T2B7E1 LYS 72  'engineered mutation' 72  38 
5 8YKR ARG E 88  ? UNP T2B7E1 GLN 88  conflict              88  39 
5 8YKR CYS E 125 ? UNP T2B7E1 HIS 125 'engineered mutation' 125 40 
5 8YKR CYS E 135 ? UNP T2B7E1 LEU 135 'engineered mutation' 135 41 
5 8YKR CYS E 139 ? UNP T2B7E1 VAL 139 'engineered mutation' 139 42 
5 8YKR CYS E 147 ? UNP T2B7E1 ASP 147 'engineered mutation' 147 43 
5 8YKR CYS E 155 ? UNP T2B7E1 ALA 155 'engineered mutation' 155 44 
5 8YKR CYS E 163 ? UNP T2B7E1 TYR 163 'engineered mutation' 163 45 
6 8YKR CYS F 44  ? UNP T2B7E1 ALA 44  'engineered mutation' 44  46 
6 8YKR CYS F 72  ? UNP T2B7E1 LYS 72  'engineered mutation' 72  47 
6 8YKR ARG F 88  ? UNP T2B7E1 GLN 88  conflict              88  48 
6 8YKR CYS F 125 ? UNP T2B7E1 HIS 125 'engineered mutation' 125 49 
6 8YKR CYS F 135 ? UNP T2B7E1 LEU 135 'engineered mutation' 135 50 
6 8YKR CYS F 139 ? UNP T2B7E1 VAL 139 'engineered mutation' 139 51 
6 8YKR CYS F 147 ? UNP T2B7E1 ASP 147 'engineered mutation' 147 52 
6 8YKR CYS F 155 ? UNP T2B7E1 ALA 155 'engineered mutation' 155 53 
6 8YKR CYS F 163 ? UNP T2B7E1 TYR 163 'engineered mutation' 163 54 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   24-meric 
_pdbx_struct_assembly.oligomeric_count     24 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 91000  ? 
1 MORE         -1108  ? 
1 'SSA (A^2)'  135190 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1,2,3,4 A,B,F,G,H,I,O,P,Q,R,V 
1 5,6,7,8 C,D,E,J,K,L,M,N,S,T,U 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'native gel electrophoresis' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z               1.0000000000  0.0000000000  0.0000000000 0.0000000000   0.0000000000  
1.0000000000  0.0000000000 0.0000000000   0.0000000000 0.0000000000 1.0000000000 0.0000000000  
2 'crystal symmetry operation' 2_555 -x,-y,z             -1.0000000000 0.0000000000  0.0000000000 0.0000000000   0.0000000000  
-1.0000000000 0.0000000000 0.0000000000   0.0000000000 0.0000000000 1.0000000000 0.0000000000  
3 'crystal symmetry operation' 3_555 -y,x,z              0.0000000000  -1.0000000000 0.0000000000 0.0000000000   1.0000000000  
0.0000000000  0.0000000000 0.0000000000   0.0000000000 0.0000000000 1.0000000000 0.0000000000  
4 'crystal symmetry operation' 4_555 y,-x,z              0.0000000000  1.0000000000  0.0000000000 0.0000000000   -1.0000000000 
0.0000000000  0.0000000000 0.0000000000   0.0000000000 0.0000000000 1.0000000000 0.0000000000  
5 'crystal symmetry operation' 5_455 x-1/2,y+1/2,z+1/2   1.0000000000  0.0000000000  0.0000000000 -62.5400000000 0.0000000000  
1.0000000000  0.0000000000 62.5400000000  0.0000000000 0.0000000000 1.0000000000 87.9585000000 
6 'crystal symmetry operation' 6_545 -x+1/2,-y-1/2,z+1/2 -1.0000000000 0.0000000000  0.0000000000 62.5400000000  0.0000000000  
-1.0000000000 0.0000000000 -62.5400000000 0.0000000000 0.0000000000 1.0000000000 87.9585000000 
7 'crystal symmetry operation' 7_445 -y-1/2,x-1/2,z+1/2  0.0000000000  -1.0000000000 0.0000000000 -62.5400000000 1.0000000000  
0.0000000000  0.0000000000 -62.5400000000 0.0000000000 0.0000000000 1.0000000000 87.9585000000 
8 'crystal symmetry operation' 8_555 y+1/2,-x+1/2,z+1/2  0.0000000000  1.0000000000  0.0000000000 62.5400000000  -1.0000000000 
0.0000000000  0.0000000000 62.5400000000  0.0000000000 0.0000000000 1.0000000000 87.9585000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 HIS A 10  ? PHE A 38  ? HIS B 10  PHE B 38  1 ? 29 
HELX_P HELX_P2  AA2 LEU A 45  ? ARG A 73  ? LEU B 45  ARG B 73  1 ? 29 
HELX_P HELX_P3  AA3 THR A 92  ? ASN A 121 ? THR B 92  ASN B 121 1 ? 30 
HELX_P HELX_P4  AA4 ASP A 123 ? GLU A 133 ? ASP B 123 GLU B 133 1 ? 11 
HELX_P HELX_P5  AA5 TYR A 134 ? CYS A 155 ? TYR B 134 CYS B 155 1 ? 22 
HELX_P HELX_P6  AA6 GLY A 159 ? ASN A 170 ? GLY B 159 ASN B 170 1 ? 12 
HELX_P HELX_P7  AA7 HIS B 10  ? PHE B 38  ? HIS A 10  PHE A 38  1 ? 29 
HELX_P HELX_P8  AA8 LEU B 45  ? ARG B 73  ? LEU A 45  ARG A 73  1 ? 29 
HELX_P HELX_P9  AA9 THR B 92  ? GLY B 120 ? THR A 92  GLY A 120 1 ? 29 
HELX_P HELX_P10 AB1 ASP B 123 ? CYS B 139 ? ASP A 123 CYS A 139 1 ? 17 
HELX_P HELX_P11 AB2 ASP B 140 ? GLY B 156 ? ASP A 140 GLY A 156 1 ? 17 
HELX_P HELX_P12 AB3 THR B 158 ? GLU B 168 ? THR A 158 GLU A 168 1 ? 11 
HELX_P HELX_P13 AB4 HIS C 10  ? PHE C 38  ? HIS C 10  PHE C 38  1 ? 29 
HELX_P HELX_P14 AB5 LEU C 45  ? GLY C 74  ? LEU C 45  GLY C 74  1 ? 30 
HELX_P HELX_P15 AB6 THR C 92  ? GLY C 120 ? THR C 92  GLY C 120 1 ? 29 
HELX_P HELX_P16 AB7 ASP C 123 ? CYS C 135 ? ASP C 123 CYS C 135 1 ? 13 
HELX_P HELX_P17 AB8 GLU C 137 ? GLY C 156 ? GLU C 137 GLY C 156 1 ? 20 
HELX_P HELX_P18 AB9 GLY C 159 ? ASN C 170 ? GLY C 159 ASN C 170 1 ? 12 
HELX_P HELX_P19 AC1 HIS D 10  ? PHE D 38  ? HIS D 10  PHE D 38  1 ? 29 
HELX_P HELX_P20 AC2 LEU D 45  ? ARG D 73  ? LEU D 45  ARG D 73  1 ? 29 
HELX_P HELX_P21 AC3 THR D 92  ? ALA D 118 ? THR D 92  ALA D 118 1 ? 27 
HELX_P HELX_P22 AC4 ASP D 123 ? TYR D 134 ? ASP D 123 TYR D 134 1 ? 12 
HELX_P HELX_P23 AC5 GLU D 137 ? CYS D 155 ? GLU D 137 CYS D 155 1 ? 19 
HELX_P HELX_P24 AC6 GLY D 159 ? ASN D 170 ? GLY D 159 ASN D 170 1 ? 12 
HELX_P HELX_P25 AC7 HIS E 10  ? PHE E 38  ? HIS E 10  PHE E 38  1 ? 29 
HELX_P HELX_P26 AC8 LEU E 45  ? ARG E 73  ? LEU E 45  ARG E 73  1 ? 29 
HELX_P HELX_P27 AC9 THR E 92  ? GLY E 120 ? THR E 92  GLY E 120 1 ? 29 
HELX_P HELX_P28 AD1 ASP E 123 ? GLU E 137 ? ASP E 123 GLU E 137 1 ? 15 
HELX_P HELX_P29 AD2 GLU E 137 ? GLY E 156 ? GLU E 137 GLY E 156 1 ? 20 
HELX_P HELX_P30 AD3 GLY E 159 ? ASN E 170 ? GLY E 159 ASN E 170 1 ? 12 
HELX_P HELX_P31 AD4 HIS F 10  ? PHE F 38  ? HIS F 10  PHE F 38  1 ? 29 
HELX_P HELX_P32 AD5 LEU F 45  ? ARG F 73  ? LEU F 45  ARG F 73  1 ? 29 
HELX_P HELX_P33 AD6 THR F 92  ? ASN F 121 ? THR F 92  ASN F 121 1 ? 30 
HELX_P HELX_P34 AD7 ASP F 123 ? CYS F 135 ? ASP F 123 CYS F 135 1 ? 13 
HELX_P HELX_P35 AD8 CYS F 135 ? CYS F 155 ? CYS F 135 CYS F 155 1 ? 21 
HELX_P HELX_P36 AD9 GLY F 159 ? ASN F 170 ? GLY F 159 ASN F 170 1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 44  SG  ? ? ? 1_555 A CYS 147 SG ? ? B CYS 44  B CYS 147 3_555 ? ? ? ? ? ? ? 2.139 ? ? 
disulf2  disulf ? ? A CYS 72  SG  ? ? ? 1_555 F CYS 139 SG ? ? B CYS 72  F CYS 139 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf3  disulf ? ? A CYS 125 SG  ? ? ? 1_555 F CYS 135 SG ? ? B CYS 125 F CYS 135 1_555 ? ? ? ? ? ? ? 1.889 ? ? 
disulf4  disulf ? ? A CYS 135 SG  ? ? ? 1_555 B CYS 125 SG ? ? B CYS 135 A CYS 125 4_555 ? ? ? ? ? ? ? 1.986 ? ? 
disulf5  disulf ? ? A CYS 139 SG  ? ? ? 1_555 B CYS 72  SG ? ? B CYS 139 A CYS 72  4_555 ? ? ? ? ? ? ? 2.068 ? ? 
disulf6  disulf ? ? A CYS 155 SG  ? ? ? 1_555 A CYS 163 SG ? ? B CYS 155 B CYS 163 4_555 ? ? ? ? ? ? ? 2.067 ? ? 
disulf7  disulf ? ? B CYS 44  SG  ? ? ? 1_555 F CYS 147 SG ? ? A CYS 44  F CYS 147 1_555 ? ? ? ? ? ? ? 2.139 ? ? 
disulf8  disulf ? ? B CYS 135 SG  ? ? ? 1_555 F CYS 125 SG ? ? A CYS 135 F CYS 125 3_555 ? ? ? ? ? ? ? 1.986 ? ? 
disulf9  disulf ? ? B CYS 139 SG  ? ? ? 1_555 F CYS 72  SG ? ? A CYS 139 F CYS 72  3_555 ? ? ? ? ? ? ? 2.017 ? ? 
disulf10 disulf ? ? B CYS 147 SG  ? ? ? 1_555 C CYS 44  SG ? ? A CYS 147 C CYS 44  6_545 ? ? ? ? ? ? ? 2.006 ? ? 
disulf11 disulf ? ? B CYS 155 SG  ? ? ? 1_555 C CYS 163 SG ? ? A CYS 155 C CYS 163 6_545 ? ? ? ? ? ? ? 2.072 ? ? 
disulf12 disulf ? ? B CYS 163 SG  ? ? ? 1_555 F CYS 155 SG ? ? A CYS 163 F CYS 155 1_555 ? ? ? ? ? ? ? 2.064 ? ? 
disulf13 disulf ? ? C CYS 72  SG  ? ? ? 1_555 D CYS 139 SG ? ? C CYS 72  D CYS 139 3_545 ? ? ? ? ? ? ? 2.029 ? ? 
disulf14 disulf ? ? C CYS 125 SG  ? ? ? 1_555 D CYS 135 SG ? ? C CYS 125 D CYS 135 3_545 ? ? ? ? ? ? ? 2.008 ? ? 
disulf15 disulf ? ? C CYS 135 SG  ? ? ? 1_555 E CYS 125 SG ? ? C CYS 135 E CYS 125 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
disulf16 disulf ? ? C CYS 139 SG  ? ? ? 1_555 E CYS 72  SG ? ? C CYS 139 E CYS 72  1_555 ? ? ? ? ? ? ? 1.924 ? ? 
disulf17 disulf ? ? C CYS 147 SG  ? ? ? 1_555 D CYS 44  SG ? ? C CYS 147 D CYS 44  1_555 ? ? ? ? ? ? ? 2.177 ? ? 
disulf18 disulf ? ? C CYS 155 SG  ? ? ? 1_555 D CYS 163 SG ? ? C CYS 155 D CYS 163 1_555 ? ? ? ? ? ? ? 2.067 ? ? 
disulf19 disulf ? ? D CYS 147 SG  ? ? ? 1_555 F CYS 44  SG ? ? D CYS 147 F CYS 44  6_544 ? ? ? ? ? ? ? 2.030 ? ? 
disulf20 disulf ? ? D CYS 155 SG  ? ? ? 1_555 F CYS 163 SG ? ? D CYS 155 F CYS 163 6_544 ? ? ? ? ? ? ? 2.063 ? ? 
disulf21 disulf ? ? E CYS 44  SG  ? ? ? 1_555 E CYS 147 SG ? ? E CYS 44  E CYS 147 4_655 ? ? ? ? ? ? ? 2.109 ? ? 
disulf22 disulf ? ? E CYS 155 SG  ? ? ? 1_555 E CYS 163 SG ? ? E CYS 155 E CYS 163 3_545 ? ? ? ? ? ? ? 2.049 ? ? 
metalc1  metalc ? ? A GLU 24  OE1 ? ? ? 1_555 G FE  .   FE ? ? B GLU 24  B FE  201 1_555 ? ? ? ? ? ? ? 2.787 ? ? 
metalc2  metalc ? ? A GLU 59  OE1 ? ? ? 1_555 G FE  .   FE ? ? B GLU 59  B FE  201 1_555 ? ? ? ? ? ? ? 2.719 ? ? 
metalc3  metalc ? ? B GLU 24  OE2 ? ? ? 1_555 I FE  .   FE ? ? A GLU 24  A FE  201 1_555 ? ? ? ? ? ? ? 2.794 ? ? 
metalc4  metalc ? ? B GLU 59  OE2 ? ? ? 1_555 I FE  .   FE ? ? A GLU 59  A FE  201 1_555 ? ? ? ? ? ? ? 2.591 ? ? 
metalc5  metalc ? ? C GLU 59  OE1 ? ? ? 1_555 J FE  .   FE ? ? C GLU 59  C FE  201 1_555 ? ? ? ? ? ? ? 2.778 ? ? 
metalc6  metalc ? ? D GLU 59  OE1 ? ? ? 1_555 K FE  .   FE ? ? D GLU 59  D FE  201 1_555 ? ? ? ? ? ? ? 2.480 ? ? 
metalc7  metalc ? ? D GLN 138 NE2 ? ? ? 1_555 L FE  .   FE ? ? D GLN 138 D FE  202 1_555 ? ? ? ? ? ? ? 2.388 ? ? 
metalc8  metalc ? ? E GLU 24  OE1 ? ? ? 1_555 M FE  .   FE ? ? E GLU 24  E FE  201 1_555 ? ? ? ? ? ? ? 2.403 ? ? 
metalc9  metalc ? ? E GLU 59  OE1 ? ? ? 1_555 M FE  .   FE ? ? E GLU 59  E FE  201 1_555 ? ? ? ? ? ? ? 2.429 ? ? 
metalc10 metalc ? ? E GLU 59  OE2 ? ? ? 1_555 N FE  .   FE ? ? E GLU 59  E FE  202 1_555 ? ? ? ? ? ? ? 2.728 ? ? 
metalc11 metalc ? ? F GLU 24  OE1 ? ? ? 1_555 O FE  .   FE ? ? F GLU 24  F FE  201 1_555 ? ? ? ? ? ? ? 2.229 ? ? 
metalc12 metalc ? ? F GLU 59  OE1 ? ? ? 1_555 O FE  .   FE ? ? F GLU 59  F FE  201 1_555 ? ? ? ? ? ? ? 2.706 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OE1 ? A GLU 24 ? B GLU 24 ? 1_555 FE ? G FE . ? B FE 201 ? 1_555 OE1 ? A GLU 59 ? B GLU 59 ? 1_555 58.5 ? 
2 OE2 ? B GLU 24 ? A GLU 24 ? 1_555 FE ? I FE . ? A FE 201 ? 1_555 OE2 ? B GLU 59 ? A GLU 59 ? 1_555 58.5 ? 
3 OE1 ? E GLU 24 ? E GLU 24 ? 1_555 FE ? M FE . ? E FE 201 ? 1_555 OE1 ? E GLU 59 ? E GLU 59 ? 1_555 65.4 ? 
4 OE1 ? F GLU 24 ? F GLU 24 ? 1_555 FE ? O FE . ? F FE 201 ? 1_555 OE1 ? F GLU 59 ? F GLU 59 ? 1_555 63.3 ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  CYS A 44  ? CYS A 147 ? CYS B 44  ? 1_555 CYS B 147 ? 3_555 SG SG . . . None 'Disulfide bridge' 
2  CYS A 72  ? CYS F 139 ? CYS B 72  ? 1_555 CYS F 139 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3  CYS A 125 ? CYS F 135 ? CYS B 125 ? 1_555 CYS F 135 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4  CYS A 135 ? CYS B 125 ? CYS B 135 ? 1_555 CYS A 125 ? 4_555 SG SG . . . None 'Disulfide bridge' 
5  CYS A 139 ? CYS B 72  ? CYS B 139 ? 1_555 CYS A 72  ? 4_555 SG SG . . . None 'Disulfide bridge' 
6  CYS A 155 ? CYS A 163 ? CYS B 155 ? 1_555 CYS B 163 ? 4_555 SG SG . . . None 'Disulfide bridge' 
7  CYS B 44  ? CYS F 147 ? CYS A 44  ? 1_555 CYS F 147 ? 1_555 SG SG . . . None 'Disulfide bridge' 
8  CYS B 135 ? CYS F 125 ? CYS A 135 ? 1_555 CYS F 125 ? 3_555 SG SG . . . None 'Disulfide bridge' 
9  CYS B 139 ? CYS F 72  ? CYS A 139 ? 1_555 CYS F 72  ? 3_555 SG SG . . . None 'Disulfide bridge' 
10 CYS B 147 ? CYS C 44  ? CYS A 147 ? 1_555 CYS C 44  ? 6_545 SG SG . . . None 'Disulfide bridge' 
11 CYS B 155 ? CYS C 163 ? CYS A 155 ? 1_555 CYS C 163 ? 6_545 SG SG . . . None 'Disulfide bridge' 
12 CYS B 163 ? CYS F 155 ? CYS A 163 ? 1_555 CYS F 155 ? 1_555 SG SG . . . None 'Disulfide bridge' 
13 CYS C 72  ? CYS D 139 ? CYS C 72  ? 1_555 CYS D 139 ? 3_545 SG SG . . . None 'Disulfide bridge' 
14 CYS C 125 ? CYS D 135 ? CYS C 125 ? 1_555 CYS D 135 ? 3_545 SG SG . . . None 'Disulfide bridge' 
15 CYS C 135 ? CYS E 125 ? CYS C 135 ? 1_555 CYS E 125 ? 1_555 SG SG . . . None 'Disulfide bridge' 
16 CYS C 139 ? CYS E 72  ? CYS C 139 ? 1_555 CYS E 72  ? 1_555 SG SG . . . None 'Disulfide bridge' 
17 CYS C 147 ? CYS D 44  ? CYS C 147 ? 1_555 CYS D 44  ? 1_555 SG SG . . . None 'Disulfide bridge' 
18 CYS C 155 ? CYS D 163 ? CYS C 155 ? 1_555 CYS D 163 ? 1_555 SG SG . . . None 'Disulfide bridge' 
19 CYS D 147 ? CYS F 44  ? CYS D 147 ? 1_555 CYS F 44  ? 6_544 SG SG . . . None 'Disulfide bridge' 
20 CYS D 155 ? CYS F 163 ? CYS D 155 ? 1_555 CYS F 163 ? 6_544 SG SG . . . None 'Disulfide bridge' 
21 CYS E 44  ? CYS E 147 ? CYS E 44  ? 1_555 CYS E 147 ? 4_655 SG SG . . . None 'Disulfide bridge' 
22 CYS E 155 ? CYS E 163 ? CYS E 155 ? 1_555 CYS E 163 ? 3_545 SG SG . . . None 'Disulfide bridge' 
# 
_pdbx_entry_details.entry_id                   8YKR 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O  C HOH 304 ? ? O C HOH 310 ? ? 2.11 
2 1 NZ E LYS 144 ? ? O E HOH 301 ? ? 2.18 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 SG  D CYS 72  ? ? 1_555 SG E CYS 139 ? ? 4_655 1.21 
2 1 SG  A CYS 135 ? ? 1_555 CB F CYS 125 ? ? 3_555 1.28 
3 1 SG  B CYS 135 ? ? 1_555 CB A CYS 125 ? ? 4_555 1.36 
4 1 SG  D CYS 125 ? ? 1_555 SG E CYS 135 ? ? 4_655 1.43 
5 1 CB  B CYS 135 ? ? 1_555 SG A CYS 125 ? ? 4_555 1.70 
6 1 NZ  A LYS 143 ? ? 1_555 O  F CYS 72  ? ? 3_555 1.85 
7 1 NH2 C ARG 88  ? ? 1_555 O  F LEU 79  ? ? 8_544 1.90 
8 1 CB  A CYS 135 ? ? 1_555 SG F CYS 125 ? ? 3_555 1.90 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA C SER 141 ? A C  C SER 141 ? ? O   C SER 141 ? ? 133.09 120.10 12.99 2.10 N 
2 1 CA C SER 141 ? B C  C SER 141 ? ? O   C SER 141 ? ? 134.29 120.10 14.19 2.10 N 
3 1 NE D ARG 88  ? ? CZ D ARG 88  ? ? NH2 D ARG 88  ? ? 123.47 120.30 3.17  0.50 N 
4 1 NE F ARG 88  ? ? CZ F ARG 88  ? ? NH2 F ARG 88  ? ? 117.06 120.30 -3.24 0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN B 8   ? ? 63.24   61.71  
2  1 VAL B 43  ? ? -125.46 -53.07 
3  1 CYS B 44  ? ? 37.26   69.33  
4  1 VAL A 43  ? ? -128.19 -59.69 
5  1 ASP A 140 ? ? -115.46 -82.27 
6  1 CYS A 155 ? ? -57.22  -9.61  
7  1 VAL C 43  ? ? -124.08 -67.96 
8  1 GLU C 136 ? ? -25.76  -51.17 
9  1 CYS C 155 ? ? -58.81  -5.82  
10 1 VAL D 43  ? ? -128.58 -66.57 
11 1 LEU D 45  ? ? -119.78 75.13  
12 1 CYS D 135 ? ? -130.71 -44.51 
13 1 CYS D 155 ? ? -56.37  -1.57  
14 1 VAL E 43  ? ? -123.79 -58.73 
15 1 VAL F 43  ? ? -126.70 -67.01 
16 1 CYS F 44  ? ? 63.34   61.30  
17 1 CYS F 72  ? ? -58.00  -71.90 
18 1 ARG F 73  ? ? -64.03  14.39  
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 ASP F 12  ? ? CYS F 13  ? ? 141.05 
2 1 GLU F 137 ? ? GLN F 138 ? ? 146.67 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 B MET 1 ? A MET 1 
2  1 Y 1 A MET 1 ? B MET 1 
3  1 Y 1 C MET 1 ? C MET 1 
4  1 Y 1 C ALA 2 ? C ALA 2 
5  1 Y 1 D MET 1 ? D MET 1 
6  1 Y 1 E MET 1 ? E MET 1 
7  1 Y 1 F MET 1 ? F MET 1 
8  1 Y 1 F ALA 2 ? F ALA 2 
9  1 Y 1 F SER 3 ? F SER 3 
10 1 Y 1 F GLN 4 ? F GLN 4 
11 1 Y 1 F VAL 5 ? F VAL 5 
12 1 Y 1 F ARG 6 ? F ARG 6 
13 1 Y 1 F GLN 7 ? F GLN 7 
14 1 Y 1 F ASN 8 ? F ASN 8 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
FE  FE   FE N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
HOH O    O  N N 159 
HOH H1   H  N N 160 
HOH H2   H  N N 161 
ILE N    N  N N 162 
ILE CA   C  N S 163 
ILE C    C  N N 164 
ILE O    O  N N 165 
ILE CB   C  N S 166 
ILE CG1  C  N N 167 
ILE CG2  C  N N 168 
ILE CD1  C  N N 169 
ILE OXT  O  N N 170 
ILE H    H  N N 171 
ILE H2   H  N N 172 
ILE HA   H  N N 173 
ILE HB   H  N N 174 
ILE HG12 H  N N 175 
ILE HG13 H  N N 176 
ILE HG21 H  N N 177 
ILE HG22 H  N N 178 
ILE HG23 H  N N 179 
ILE HD11 H  N N 180 
ILE HD12 H  N N 181 
ILE HD13 H  N N 182 
ILE HXT  H  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
PHE N    N  N N 251 
PHE CA   C  N S 252 
PHE C    C  N N 253 
PHE O    O  N N 254 
PHE CB   C  N N 255 
PHE CG   C  Y N 256 
PHE CD1  C  Y N 257 
PHE CD2  C  Y N 258 
PHE CE1  C  Y N 259 
PHE CE2  C  Y N 260 
PHE CZ   C  Y N 261 
PHE OXT  O  N N 262 
PHE H    H  N N 263 
PHE H2   H  N N 264 
PHE HA   H  N N 265 
PHE HB2  H  N N 266 
PHE HB3  H  N N 267 
PHE HD1  H  N N 268 
PHE HD2  H  N N 269 
PHE HE1  H  N N 270 
PHE HE2  H  N N 271 
PHE HZ   H  N N 272 
PHE HXT  H  N N 273 
PRO N    N  N N 274 
PRO CA   C  N S 275 
PRO C    C  N N 276 
PRO O    O  N N 277 
PRO CB   C  N N 278 
PRO CG   C  N N 279 
PRO CD   C  N N 280 
PRO OXT  O  N N 281 
PRO H    H  N N 282 
PRO HA   H  N N 283 
PRO HB2  H  N N 284 
PRO HB3  H  N N 285 
PRO HG2  H  N N 286 
PRO HG3  H  N N 287 
PRO HD2  H  N N 288 
PRO HD3  H  N N 289 
PRO HXT  H  N N 290 
SER N    N  N N 291 
SER CA   C  N S 292 
SER C    C  N N 293 
SER O    O  N N 294 
SER CB   C  N N 295 
SER OG   O  N N 296 
SER OXT  O  N N 297 
SER H    H  N N 298 
SER H2   H  N N 299 
SER HA   H  N N 300 
SER HB2  H  N N 301 
SER HB3  H  N N 302 
SER HG   H  N N 303 
SER HXT  H  N N 304 
THR N    N  N N 305 
THR CA   C  N S 306 
THR C    C  N N 307 
THR O    O  N N 308 
THR CB   C  N R 309 
THR OG1  O  N N 310 
THR CG2  C  N N 311 
THR OXT  O  N N 312 
THR H    H  N N 313 
THR H2   H  N N 314 
THR HA   H  N N 315 
THR HB   H  N N 316 
THR HG1  H  N N 317 
THR HG21 H  N N 318 
THR HG22 H  N N 319 
THR HG23 H  N N 320 
THR HXT  H  N N 321 
TRP N    N  N N 322 
TRP CA   C  N S 323 
TRP C    C  N N 324 
TRP O    O  N N 325 
TRP CB   C  N N 326 
TRP CG   C  Y N 327 
TRP CD1  C  Y N 328 
TRP CD2  C  Y N 329 
TRP NE1  N  Y N 330 
TRP CE2  C  Y N 331 
TRP CE3  C  Y N 332 
TRP CZ2  C  Y N 333 
TRP CZ3  C  Y N 334 
TRP CH2  C  Y N 335 
TRP OXT  O  N N 336 
TRP H    H  N N 337 
TRP H2   H  N N 338 
TRP HA   H  N N 339 
TRP HB2  H  N N 340 
TRP HB3  H  N N 341 
TRP HD1  H  N N 342 
TRP HE1  H  N N 343 
TRP HE3  H  N N 344 
TRP HZ2  H  N N 345 
TRP HZ3  H  N N 346 
TRP HH2  H  N N 347 
TRP HXT  H  N N 348 
TYR N    N  N N 349 
TYR CA   C  N S 350 
TYR C    C  N N 351 
TYR O    O  N N 352 
TYR CB   C  N N 353 
TYR CG   C  Y N 354 
TYR CD1  C  Y N 355 
TYR CD2  C  Y N 356 
TYR CE1  C  Y N 357 
TYR CE2  C  Y N 358 
TYR CZ   C  Y N 359 
TYR OH   O  N N 360 
TYR OXT  O  N N 361 
TYR H    H  N N 362 
TYR H2   H  N N 363 
TYR HA   H  N N 364 
TYR HB2  H  N N 365 
TYR HB3  H  N N 366 
TYR HD1  H  N N 367 
TYR HD2  H  N N 368 
TYR HE1  H  N N 369 
TYR HE2  H  N N 370 
TYR HH   H  N N 371 
TYR HXT  H  N N 372 
VAL N    N  N N 373 
VAL CA   C  N S 374 
VAL C    C  N N 375 
VAL O    O  N N 376 
VAL CB   C  N N 377 
VAL CG1  C  N N 378 
VAL CG2  C  N N 379 
VAL OXT  O  N N 380 
VAL H    H  N N 381 
VAL H2   H  N N 382 
VAL HA   H  N N 383 
VAL HB   H  N N 384 
VAL HG11 H  N N 385 
VAL HG12 H  N N 386 
VAL HG13 H  N N 387 
VAL HG21 H  N N 388 
VAL HG22 H  N N 389 
VAL HG23 H  N N 390 
VAL HXT  H  N N 391 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32030084 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8YKR 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.007995 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007995 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005684 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
FE 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ALA A 1 2   ? 21.579  -55.007 64.849  1.00 63.36  ? 2   ALA B N   1 
ATOM   2    C  CA  . ALA A 1 2   ? 20.444  -54.099 64.692  1.00 71.96  ? 2   ALA B CA  1 
ATOM   3    C  C   . ALA A 1 2   ? 20.342  -53.162 65.897  1.00 78.00  ? 2   ALA B C   1 
ATOM   4    O  O   . ALA A 1 2   ? 21.016  -53.369 66.902  1.00 77.37  ? 2   ALA B O   1 
ATOM   5    C  CB  . ALA A 1 2   ? 19.132  -54.887 64.501  1.00 62.63  ? 2   ALA B CB  1 
ATOM   6    N  N   . SER A 1 3   ? 19.499  -52.134 65.791  1.00 76.01  ? 3   SER B N   1 
ATOM   7    C  CA  . SER A 1 3   ? 19.349  -51.161 66.866  1.00 69.40  ? 3   SER B CA  1 
ATOM   8    C  C   . SER A 1 3   ? 18.599  -51.747 68.060  1.00 74.87  ? 3   SER B C   1 
ATOM   9    O  O   . SER A 1 3   ? 17.790  -52.673 67.927  1.00 77.89  ? 3   SER B O   1 
ATOM   10   C  CB  . SER A 1 3   ? 18.606  -49.917 66.368  1.00 69.94  ? 3   SER B CB  1 
ATOM   11   O  OG  . SER A 1 3   ? 19.498  -48.896 65.947  1.00 74.78  ? 3   SER B OG  1 
ATOM   12   N  N   . GLN A 1 4   ? 18.878  -51.182 69.241  1.00 71.11  ? 4   GLN B N   1 
ATOM   13   C  CA  . GLN A 1 4   ? 18.029  -51.398 70.412  1.00 70.04  ? 4   GLN B CA  1 
ATOM   14   C  C   . GLN A 1 4   ? 16.567  -51.076 70.113  1.00 72.45  ? 4   GLN B C   1 
ATOM   15   O  O   . GLN A 1 4   ? 15.656  -51.729 70.639  1.00 67.72  ? 4   GLN B O   1 
ATOM   16   C  CB  . GLN A 1 4   ? 18.501  -50.512 71.563  1.00 69.83  ? 4   GLN B CB  1 
ATOM   17   C  CG  . GLN A 1 4   ? 19.350  -51.163 72.629  1.00 76.77  ? 4   GLN B CG  1 
ATOM   18   C  CD  . GLN A 1 4   ? 20.144  -50.109 73.378  1.00 69.05  ? 4   GLN B CD  1 
ATOM   19   O  OE1 . GLN A 1 4   ? 19.936  -48.899 73.161  1.00 51.27  ? 4   GLN B OE1 1 
ATOM   20   N  NE2 . GLN A 1 4   ? 21.086  -50.550 74.226  1.00 60.72  ? 4   GLN B NE2 1 
ATOM   21   N  N   . VAL A 1 5   ? 16.331  -50.055 69.291  1.00 70.24  ? 5   VAL B N   1 
ATOM   22   C  CA  . VAL A 1 5   ? 15.018  -49.444 69.129  1.00 73.34  ? 5   VAL B CA  1 
ATOM   23   C  C   . VAL A 1 5   ? 14.458  -49.667 67.720  1.00 75.08  ? 5   VAL B C   1 
ATOM   24   O  O   . VAL A 1 5   ? 13.561  -48.938 67.291  1.00 77.82  ? 5   VAL B O   1 
ATOM   25   C  CB  . VAL A 1 5   ? 15.052  -47.943 69.492  1.00 68.74  ? 5   VAL B CB  1 
ATOM   26   C  CG1 . VAL A 1 5   ? 15.638  -47.742 70.870  1.00 60.77  ? 5   VAL B CG1 1 
ATOM   27   C  CG2 . VAL A 1 5   ? 15.841  -47.118 68.453  1.00 66.17  ? 5   VAL B CG2 1 
ATOM   28   N  N   . ARG A 1 6   ? 14.966  -50.659 66.989  1.00 71.99  ? 6   ARG B N   1 
ATOM   29   C  CA  . ARG A 1 6   ? 14.389  -51.026 65.699  1.00 74.55  ? 6   ARG B CA  1 
ATOM   30   C  C   . ARG A 1 6   ? 13.308  -52.089 65.898  1.00 74.65  ? 6   ARG B C   1 
ATOM   31   O  O   . ARG A 1 6   ? 13.534  -53.109 66.565  1.00 70.50  ? 6   ARG B O   1 
ATOM   32   C  CB  . ARG A 1 6   ? 15.470  -51.515 64.726  1.00 73.70  ? 6   ARG B CB  1 
ATOM   33   C  CG  . ARG A 1 6   ? 15.078  -51.348 63.254  1.00 69.02  ? 6   ARG B CG  1 
ATOM   34   C  CD  . ARG A 1 6   ? 16.054  -52.025 62.296  1.00 72.63  ? 6   ARG B CD  1 
ATOM   35   N  NE  . ARG A 1 6   ? 15.767  -51.659 60.906  1.00 70.28  ? 6   ARG B NE  1 
ATOM   36   C  CZ  . ARG A 1 6   ? 16.668  -51.201 60.041  1.00 69.13  ? 6   ARG B CZ  1 
ATOM   37   N  NH1 . ARG A 1 6   ? 16.303  -50.888 58.801  1.00 66.75  ? 6   ARG B NH1 1 
ATOM   38   N  NH2 . ARG A 1 6   ? 17.933  -51.048 60.413  1.00 59.70  ? 6   ARG B NH2 1 
ATOM   39   N  N   . GLN A 1 7   ? 12.129  -51.829 65.331  1.00 75.51  ? 7   GLN B N   1 
ATOM   40   C  CA  . GLN A 1 7   ? 10.993  -52.749 65.400  1.00 75.81  ? 7   GLN B CA  1 
ATOM   41   C  C   . GLN A 1 7   ? 10.077  -52.447 64.221  1.00 76.62  ? 7   GLN B C   1 
ATOM   42   O  O   . GLN A 1 7   ? 9.565   -51.325 64.121  1.00 79.47  ? 7   GLN B O   1 
ATOM   43   C  CB  . GLN A 1 7   ? 10.252  -52.594 66.741  1.00 72.22  ? 7   GLN B CB  1 
ATOM   44   C  CG  . GLN A 1 7   ? 8.933   -53.357 66.851  1.00 77.53  ? 7   GLN B CG  1 
ATOM   45   C  CD  . GLN A 1 7   ? 8.563   -53.691 68.296  1.00 84.12  ? 7   GLN B CD  1 
ATOM   46   O  OE1 . GLN A 1 7   ? 8.786   -54.814 68.759  1.00 83.76  ? 7   GLN B OE1 1 
ATOM   47   N  NE2 . GLN A 1 7   ? 7.994   -52.716 69.014  1.00 82.12  ? 7   GLN B NE2 1 
ATOM   48   N  N   . ASN A 1 8   ? 9.894   -53.421 63.319  1.00 74.45  ? 8   ASN B N   1 
ATOM   49   C  CA  . ASN A 1 8   ? 9.000   -53.282 62.159  1.00 77.08  ? 8   ASN B CA  1 
ATOM   50   C  C   . ASN A 1 8   ? 9.486   -52.168 61.213  1.00 81.79  ? 8   ASN B C   1 
ATOM   51   O  O   . ASN A 1 8   ? 8.805   -51.165 60.971  1.00 80.15  ? 8   ASN B O   1 
ATOM   52   C  CB  . ASN A 1 8   ? 7.553   -53.050 62.639  1.00 73.00  ? 8   ASN B CB  1 
ATOM   53   C  CG  . ASN A 1 8   ? 6.573   -52.733 61.500  1.00 79.01  ? 8   ASN B CG  1 
ATOM   54   O  OD1 . ASN A 1 8   ? 6.014   -51.625 61.426  1.00 69.02  ? 8   ASN B OD1 1 
ATOM   55   N  ND2 . ASN A 1 8   ? 6.352   -53.709 60.621  1.00 74.88  ? 8   ASN B ND2 1 
ATOM   56   N  N   . TYR A 1 9   ? 10.697  -52.351 60.666  1.00 76.61  ? 9   TYR B N   1 
ATOM   57   C  CA  . TYR A 1 9   ? 11.317  -51.267 59.889  1.00 73.60  ? 9   TYR B CA  1 
ATOM   58   C  C   . TYR A 1 9   ? 12.180  -51.871 58.773  1.00 68.62  ? 9   TYR B C   1 
ATOM   59   O  O   . TYR A 1 9   ? 13.360  -52.176 58.975  1.00 60.47  ? 9   TYR B O   1 
ATOM   60   C  CB  . TYR A 1 9   ? 12.126  -50.343 60.790  1.00 72.17  ? 9   TYR B CB  1 
ATOM   61   C  CG  . TYR A 1 9   ? 12.524  -49.040 60.119  1.00 75.36  ? 9   TYR B CG  1 
ATOM   62   C  CD1 . TYR A 1 9   ? 11.608  -48.333 59.335  1.00 72.51  ? 9   TYR B CD1 1 
ATOM   63   C  CD2 . TYR A 1 9   ? 13.819  -48.522 60.255  1.00 70.58  ? 9   TYR B CD2 1 
ATOM   64   C  CE1 . TYR A 1 9   ? 11.959  -47.153 58.714  1.00 65.83  ? 9   TYR B CE1 1 
ATOM   65   C  CE2 . TYR A 1 9   ? 14.178  -47.336 59.636  1.00 68.31  ? 9   TYR B CE2 1 
ATOM   66   C  CZ  . TYR A 1 9   ? 13.238  -46.662 58.869  1.00 63.68  ? 9   TYR B CZ  1 
ATOM   67   O  OH  . TYR A 1 9   ? 13.584  -45.500 58.248  1.00 60.93  ? 9   TYR B OH  1 
ATOM   68   N  N   . HIS A 1 10  ? 11.583  -51.994 57.585  1.00 71.60  ? 10  HIS B N   1 
ATOM   69   C  CA  . HIS A 1 10  ? 12.231  -52.662 56.462  1.00 65.76  ? 10  HIS B CA  1 
ATOM   70   C  C   . HIS A 1 10  ? 13.418  -51.851 55.942  1.00 69.44  ? 10  HIS B C   1 
ATOM   71   O  O   . HIS A 1 10  ? 13.419  -50.617 55.955  1.00 66.11  ? 10  HIS B O   1 
ATOM   72   C  CB  . HIS A 1 10  ? 11.224  -52.897 55.333  1.00 60.28  ? 10  HIS B CB  1 
ATOM   73   C  CG  . HIS A 1 10  ? 11.658  -53.938 54.344  1.00 69.76  ? 10  HIS B CG  1 
ATOM   74   N  ND1 . HIS A 1 10  ? 12.554  -53.675 53.327  1.00 70.00  ? 10  HIS B ND1 1 
ATOM   75   C  CD2 . HIS A 1 10  ? 11.317  -55.244 54.216  1.00 63.20  ? 10  HIS B CD2 1 
ATOM   76   C  CE1 . HIS A 1 10  ? 12.744  -54.772 52.616  1.00 69.06  ? 10  HIS B CE1 1 
ATOM   77   N  NE2 . HIS A 1 10  ? 12.009  -55.739 53.137  1.00 71.28  ? 10  HIS B NE2 1 
ATOM   78   N  N   . GLU A 1 11  ? 14.439  -52.562 55.462  1.00 68.01  ? 11  GLU B N   1 
ATOM   79   C  CA  . GLU A 1 11  ? 15.637  -51.878 54.998  1.00 59.90  ? 11  GLU B CA  1 
ATOM   80   C  C   . GLU A 1 11  ? 15.394  -51.078 53.722  1.00 66.73  ? 11  GLU B C   1 
ATOM   81   O  O   . GLU A 1 11  ? 16.126  -50.116 53.456  1.00 64.98  ? 11  GLU B O   1 
ATOM   82   C  CB  . GLU A 1 11  ? 16.763  -52.888 54.788  1.00 62.90  ? 11  GLU B CB  1 
ATOM   83   C  CG  . GLU A 1 11  ? 16.672  -53.679 53.484  1.00 74.68  ? 11  GLU B CG  1 
ATOM   84   C  CD  . GLU A 1 11  ? 17.961  -54.412 53.162  1.00 79.01  ? 11  GLU B CD  1 
ATOM   85   O  OE1 . GLU A 1 11  ? 18.720  -54.714 54.109  1.00 84.53  ? 11  GLU B OE1 1 
ATOM   86   O  OE2 . GLU A 1 11  ? 18.216  -54.687 51.968  1.00 83.93  ? 11  GLU B OE2 1 
ATOM   87   N  N   . ASP A 1 12  ? 14.389  -51.441 52.923  1.00 63.30  ? 12  ASP B N   1 
ATOM   88   C  CA  . ASP A 1 12  ? 14.101  -50.647 51.736  1.00 67.17  ? 12  ASP B CA  1 
ATOM   89   C  C   . ASP A 1 12  ? 13.573  -49.273 52.114  1.00 65.33  ? 12  ASP B C   1 
ATOM   90   O  O   . ASP A 1 12  ? 13.997  -48.260 51.539  1.00 61.15  ? 12  ASP B O   1 
ATOM   91   C  CB  . ASP A 1 12  ? 13.114  -51.380 50.840  1.00 70.11  ? 12  ASP B CB  1 
ATOM   92   C  CG  . ASP A 1 12  ? 13.780  -52.466 50.055  1.00 72.67  ? 12  ASP B CG  1 
ATOM   93   O  OD1 . ASP A 1 12  ? 15.032  -52.505 50.115  1.00 66.91  ? 12  ASP B OD1 1 
ATOM   94   O  OD2 . ASP A 1 12  ? 13.068  -53.269 49.401  1.00 77.07  ? 12  ASP B OD2 1 
ATOM   95   N  N   . CYS A 1 13  ? 12.654  -49.221 53.084  1.00 55.17  ? 13  CYS B N   1 
ATOM   96   C  CA  . CYS A 1 13  ? 12.214  -47.935 53.595  1.00 56.93  ? 13  CYS B CA  1 
ATOM   97   C  C   . CYS A 1 13  ? 13.386  -47.136 54.155  1.00 60.39  ? 13  CYS B C   1 
ATOM   98   O  O   . CYS A 1 13  ? 13.414  -45.908 54.028  1.00 58.55  ? 13  CYS B O   1 
ATOM   99   C  CB  . CYS A 1 13  ? 11.114  -48.125 54.646  1.00 70.48  ? 13  CYS B CB  1 
ATOM   100  S  SG  . CYS A 1 13  ? 9.703   -49.209 54.151  1.00 67.81  ? 13  CYS B SG  1 
ATOM   101  N  N   . GLU A 1 14  ? 14.383  -47.806 54.734  1.00 56.19  ? 14  GLU B N   1 
ATOM   102  C  CA  . GLU A 1 14  ? 15.546  -47.080 55.238  1.00 58.26  ? 14  GLU B CA  1 
ATOM   103  C  C   . GLU A 1 14  ? 16.355  -46.479 54.091  1.00 56.44  ? 14  GLU B C   1 
ATOM   104  O  O   . GLU A 1 14  ? 16.850  -45.346 54.192  1.00 49.29  ? 14  GLU B O   1 
ATOM   105  C  CB  . GLU A 1 14  ? 16.408  -48.004 56.105  1.00 55.43  ? 14  GLU B CB  1 
ATOM   106  C  CG  . GLU A 1 14  ? 17.870  -47.587 56.260  1.00 55.82  ? 14  GLU B CG  1 
ATOM   107  C  CD  . GLU A 1 14  ? 18.595  -48.348 57.379  1.00 62.07  ? 14  GLU B CD  1 
ATOM   108  O  OE1 . GLU A 1 14  ? 18.073  -49.396 57.825  1.00 63.84  ? 14  GLU B OE1 1 
ATOM   109  O  OE2 . GLU A 1 14  ? 19.686  -47.895 57.811  1.00 57.07  ? 14  GLU B OE2 1 
ATOM   110  N  N   . ALA A 1 15  ? 16.473  -47.204 52.976  1.00 52.51  ? 15  ALA B N   1 
ATOM   111  C  CA  . ALA A 1 15  ? 17.184  -46.636 51.838  1.00 49.55  ? 15  ALA B CA  1 
ATOM   112  C  C   . ALA A 1 15  ? 16.396  -45.487 51.222  1.00 52.16  ? 15  ALA B C   1 
ATOM   113  O  O   . ALA A 1 15  ? 16.973  -44.444 50.896  1.00 46.32  ? 15  ALA B O   1 
ATOM   114  C  CB  . ALA A 1 15  ? 17.479  -47.713 50.797  1.00 40.96  ? 15  ALA B CB  1 
ATOM   115  N  N   . SER A 1 16  ? 15.076  -45.651 51.068  1.00 48.39  ? 16  SER B N   1 
ATOM   116  C  CA  . SER A 1 16  ? 14.291  -44.606 50.417  1.00 52.74  ? 16  SER B CA  1 
ATOM   117  C  C   . SER A 1 16  ? 14.238  -43.350 51.268  1.00 49.99  ? 16  SER B C   1 
ATOM   118  O  O   . SER A 1 16  ? 14.222  -42.238 50.730  1.00 51.80  ? 16  SER B O   1 
ATOM   119  C  CB  . SER A 1 16  ? 12.870  -45.087 50.095  1.00 57.16  ? 16  SER B CB  1 
ATOM   120  O  OG  . SER A 1 16  ? 12.847  -46.281 49.322  1.00 66.29  ? 16  SER B OG  1 
ATOM   121  N  N   . ILE A 1 17  ? 14.200  -43.502 52.595  1.00 49.04  ? 17  ILE B N   1 
ATOM   122  C  CA  . ILE A 1 17  ? 14.309  -42.340 53.471  1.00 49.13  ? 17  ILE B CA  1 
ATOM   123  C  C   . ILE A 1 17  ? 15.597  -41.572 53.176  1.00 49.28  ? 17  ILE B C   1 
ATOM   124  O  O   . ILE A 1 17  ? 15.597  -40.336 53.103  1.00 44.28  ? 17  ILE B O   1 
ATOM   125  C  CB  . ILE A 1 17  ? 14.220  -42.757 54.954  1.00 48.05  ? 17  ILE B CB  1 
ATOM   126  C  CG1 . ILE A 1 17  ? 12.851  -43.357 55.294  1.00 53.03  ? 17  ILE B CG1 1 
ATOM   127  C  CG2 . ILE A 1 17  ? 14.466  -41.569 55.862  1.00 44.54  ? 17  ILE B CG2 1 
ATOM   128  C  CD1 . ILE A 1 17  ? 11.808  -42.337 55.667  1.00 61.17  ? 17  ILE B CD1 1 
ATOM   129  N  N   . ASN A 1 18  ? 16.705  -42.290 52.964  1.00 46.38  ? 18  ASN B N   1 
ATOM   130  C  CA  . ASN A 1 18  ? 17.958  -41.609 52.652  1.00 42.41  ? 18  ASN B CA  1 
ATOM   131  C  C   . ASN A 1 18  ? 17.887  -40.919 51.298  1.00 42.60  ? 18  ASN B C   1 
ATOM   132  O  O   . ASN A 1 18  ? 18.429  -39.820 51.134  1.00 46.37  ? 18  ASN B O   1 
ATOM   133  C  CB  . ASN A 1 18  ? 19.132  -42.580 52.689  1.00 39.29  ? 18  ASN B CB  1 
ATOM   134  C  CG  . ASN A 1 18  ? 19.613  -42.865 54.105  1.00 44.83  ? 18  ASN B CG  1 
ATOM   135  O  OD1 . ASN A 1 18  ? 19.502  -42.024 54.998  1.00 44.72  ? 18  ASN B OD1 1 
ATOM   136  N  ND2 . ASN A 1 18  ? 20.122  -44.074 54.323  1.00 41.96  ? 18  ASN B ND2 1 
ATOM   137  N  N   . LYS A 1 19  ? 17.207  -41.512 50.317  1.00 44.45  ? 19  LYS B N   1 
ATOM   138  C  CA  . LYS A 1 19  ? 17.090  -40.784 49.060  1.00 44.46  ? 19  LYS B CA  1 
ATOM   139  C  C   . LYS A 1 19  ? 16.226  -39.537 49.240  1.00 45.41  ? 19  LYS B C   1 
ATOM   140  O  O   . LYS A 1 19  ? 16.548  -38.470 48.703  1.00 42.35  ? 19  LYS B O   1 
ATOM   141  C  CB  . LYS A 1 19  ? 16.555  -41.675 47.939  1.00 34.56  ? 19  LYS B CB  1 
ATOM   142  C  CG  . LYS A 1 19  ? 16.393  -40.898 46.578  1.00 57.39  ? 19  LYS B CG  1 
ATOM   143  C  CD  . LYS A 1 19  ? 17.567  -39.871 46.268  1.00 64.30  ? 19  LYS B CD  1 
ATOM   144  C  CE  . LYS A 1 19  ? 17.077  -38.610 45.479  1.00 58.29  ? 19  LYS B CE  1 
ATOM   145  N  NZ  . LYS A 1 19  ? 17.958  -37.333 45.535  1.00 53.54  ? 19  LYS B NZ  1 
ATOM   146  N  N   . GLN A 1 20  ? 15.163  -39.636 50.046  1.00 46.18  ? 20  GLN B N   1 
ATOM   147  C  CA  . GLN A 1 20  ? 14.294  -38.485 50.265  1.00 40.88  ? 20  GLN B CA  1 
ATOM   148  C  C   . GLN A 1 20  ? 15.025  -37.377 50.989  1.00 41.80  ? 20  GLN B C   1 
ATOM   149  O  O   . GLN A 1 20  ? 14.729  -36.198 50.772  1.00 40.16  ? 20  GLN B O   1 
ATOM   150  C  CB  . GLN A 1 20  ? 13.052  -38.879 51.064  1.00 44.81  ? 20  GLN B CB  1 
ATOM   151  C  CG  . GLN A 1 20  ? 12.005  -37.790 51.102  1.00 47.42  ? 20  GLN B CG  1 
ATOM   152  C  CD  . GLN A 1 20  ? 11.387  -37.571 49.726  1.00 54.78  ? 20  GLN B CD  1 
ATOM   153  O  OE1 . GLN A 1 20  ? 11.387  -38.482 48.894  1.00 47.20  ? 20  GLN B OE1 1 
ATOM   154  N  NE2 . GLN A 1 20  ? 10.877  -36.360 49.474  1.00 51.55  ? 20  GLN B NE2 1 
ATOM   155  N  N   . ILE A 1 21  ? 15.969  -37.738 51.861  1.00 40.82  ? 21  ILE B N   1 
ATOM   156  C  CA  . ILE A 1 21  ? 16.757  -36.732 52.563  1.00 37.50  ? 21  ILE B CA  1 
ATOM   157  C  C   . ILE A 1 21  ? 17.578  -35.923 51.562  1.00 37.84  ? 21  ILE B C   1 
ATOM   158  O  O   . ILE A 1 21  ? 17.600  -34.688 51.606  1.00 37.77  ? 21  ILE B O   1 
ATOM   159  C  CB  . ILE A 1 21  ? 17.648  -37.404 53.621  1.00 35.07  ? 21  ILE B CB  1 
ATOM   160  C  CG1 . ILE A 1 21  ? 16.793  -37.910 54.775  1.00 38.41  ? 21  ILE B CG1 1 
ATOM   161  C  CG2 . ILE A 1 21  ? 18.769  -36.450 54.078  1.00 27.98  ? 21  ILE B CG2 1 
ATOM   162  C  CD1 . ILE A 1 21  ? 17.503  -38.902 55.667  1.00 39.81  ? 21  ILE B CD1 1 
ATOM   163  N  N   . ASN A 1 22  ? 18.248  -36.614 50.630  1.00 35.17  ? 22  ASN B N   1 
ATOM   164  C  CA  . ASN A 1 22  ? 19.044  -35.922 49.625  1.00 35.72  ? 22  ASN B CA  1 
ATOM   165  C  C   . ASN A 1 22  ? 18.157  -35.069 48.740  1.00 35.65  ? 22  ASN B C   1 
ATOM   166  O  O   . ASN A 1 22  ? 18.534  -33.958 48.345  1.00 33.65  ? 22  ASN B O   1 
ATOM   167  C  CB  . ASN A 1 22  ? 19.838  -36.918 48.770  1.00 31.98  ? 22  ASN B CB  1 
ATOM   168  C  CG  . ASN A 1 22  ? 20.875  -36.222 47.893  1.00 36.83  ? 22  ASN B CG  1 
ATOM   169  O  OD1 . ASN A 1 22  ? 20.595  -35.863 46.741  1.00 39.01  ? 22  ASN B OD1 1 
ATOM   170  N  ND2 . ASN A 1 22  ? 22.075  -35.998 48.445  1.00 37.10  ? 22  ASN B ND2 1 
ATOM   171  N  N   . MET A 1 23  ? 16.980  -35.584 48.402  1.00 33.36  ? 23  MET B N   1 
ATOM   172  C  CA  . MET A 1 23  ? 16.064  -34.817 47.579  1.00 37.89  ? 23  MET B CA  1 
ATOM   173  C  C   . MET A 1 23  ? 15.685  -33.508 48.270  1.00 39.08  ? 23  MET B C   1 
ATOM   174  O  O   . MET A 1 23  ? 15.696  -32.441 47.645  1.00 34.12  ? 23  MET B O   1 
ATOM   175  C  CB  . MET A 1 23  ? 14.837  -35.665 47.260  1.00 36.24  ? 23  MET B CB  1 
ATOM   176  C  CG  . MET A 1 23  ? 13.777  -34.913 46.486  1.00 45.26  ? 23  MET B CG  1 
ATOM   177  S  SD  . MET A 1 23  ? 14.119  -34.884 44.722  1.00 71.10  ? 23  MET B SD  1 
ATOM   178  C  CE  . MET A 1 23  ? 13.704  -36.578 44.313  1.00 62.77  ? 23  MET B CE  1 
ATOM   179  N  N   . GLU A 1 24  ? 15.387  -33.560 49.569  1.00 33.35  ? 24  GLU B N   1 
ATOM   180  C  CA  . GLU A 1 24  ? 15.039  -32.331 50.276  1.00 42.34  ? 24  GLU B CA  1 
ATOM   181  C  C   . GLU A 1 24  ? 16.236  -31.387 50.372  1.00 36.51  ? 24  GLU B C   1 
ATOM   182  O  O   . GLU A 1 24  ? 16.092  -30.165 50.201  1.00 32.24  ? 24  GLU B O   1 
ATOM   183  C  CB  . GLU A 1 24  ? 14.493  -32.650 51.673  1.00 42.09  ? 24  GLU B CB  1 
ATOM   184  C  CG  . GLU A 1 24  ? 13.304  -33.615 51.698  1.00 47.21  ? 24  GLU B CG  1 
ATOM   185  C  CD  . GLU A 1 24  ? 12.001  -32.975 51.267  1.00 57.42  ? 24  GLU B CD  1 
ATOM   186  O  OE1 . GLU A 1 24  ? 12.016  -31.761 50.966  1.00 53.39  ? 24  GLU B OE1 1 
ATOM   187  O  OE2 . GLU A 1 24  ? 10.961  -33.683 51.237  1.00 67.43  ? 24  GLU B OE2 1 
ATOM   188  N  N   . LEU A 1 25  ? 17.424  -31.928 50.651  1.00 33.98  ? 25  LEU B N   1 
ATOM   189  C  CA  . LEU A 1 25  ? 18.605  -31.069 50.715  1.00 35.11  ? 25  LEU B CA  1 
ATOM   190  C  C   . LEU A 1 25  ? 18.858  -30.414 49.366  1.00 34.45  ? 25  LEU B C   1 
ATOM   191  O  O   . LEU A 1 25  ? 19.172  -29.220 49.300  1.00 33.62  ? 25  LEU B O   1 
ATOM   192  C  CB  . LEU A 1 25  ? 19.812  -31.877 51.185  1.00 33.31  ? 25  LEU B CB  1 
ATOM   193  C  CG  . LEU A 1 25  ? 19.702  -32.171 52.690  1.00 33.42  ? 25  LEU B CG  1 
ATOM   194  C  CD1 . LEU A 1 25  ? 20.737  -33.200 53.154  1.00 32.18  ? 25  LEU B CD1 1 
ATOM   195  C  CD2 . LEU A 1 25  ? 19.807  -30.881 53.517  1.00 26.19  ? 25  LEU B CD2 1 
ATOM   196  N  N   . TYR A 1 26  ? 18.661  -31.179 48.282  1.00 30.47  ? 26  TYR B N   1 
ATOM   197  C  CA  . TYR A 1 26  ? 18.771  -30.669 46.920  1.00 33.26  ? 26  TYR B CA  1 
ATOM   198  C  C   . TYR A 1 26  ? 17.757  -29.556 46.648  1.00 35.80  ? 26  TYR B C   1 
ATOM   199  O  O   . TYR A 1 26  ? 18.113  -28.494 46.109  1.00 31.63  ? 26  TYR B O   1 
ATOM   200  C  CB  . TYR A 1 26  ? 18.580  -31.819 45.923  1.00 35.16  ? 26  TYR B CB  1 
ATOM   201  C  CG  . TYR A 1 26  ? 18.507  -31.320 44.507  1.00 34.52  ? 26  TYR B CG  1 
ATOM   202  C  CD1 . TYR A 1 26  ? 19.639  -30.832 43.874  1.00 42.31  ? 26  TYR B CD1 1 
ATOM   203  C  CD2 . TYR A 1 26  ? 17.308  -31.291 43.817  1.00 37.27  ? 26  TYR B CD2 1 
ATOM   204  C  CE1 . TYR A 1 26  ? 19.585  -30.349 42.580  1.00 41.01  ? 26  TYR B CE1 1 
ATOM   205  C  CE2 . TYR A 1 26  ? 17.240  -30.829 42.525  1.00 34.60  ? 26  TYR B CE2 1 
ATOM   206  C  CZ  . TYR A 1 26  ? 18.385  -30.354 41.913  1.00 41.42  ? 26  TYR B CZ  1 
ATOM   207  O  OH  . TYR A 1 26  ? 18.338  -29.874 40.629  1.00 43.47  ? 26  TYR B OH  1 
ATOM   208  N  N   . ALA A 1 27  ? 16.478  -29.790 46.990  1.00 35.23  ? 27  ALA B N   1 
ATOM   209  C  CA  . ALA A 1 27  ? 15.458  -28.759 46.790  1.00 38.12  ? 27  ALA B CA  1 
ATOM   210  C  C   . ALA A 1 27  ? 15.808  -27.493 47.568  1.00 38.70  ? 27  ALA B C   1 
ATOM   211  O  O   . ALA A 1 27  ? 15.680  -26.374 47.050  1.00 36.00  ? 27  ALA B O   1 
ATOM   212  C  CB  . ALA A 1 27  ? 14.077  -29.278 47.203  1.00 31.21  ? 27  ALA B CB  1 
ATOM   213  N  N   . SER A 1 28  ? 16.272  -27.661 48.808  1.00 30.53  ? 28  SER B N   1 
ATOM   214  C  CA  . SER A 1 28  ? 16.788  -26.548 49.588  1.00 32.26  ? 28  SER B CA  1 
ATOM   215  C  C   . SER A 1 28  ? 17.852  -25.773 48.817  1.00 36.43  ? 28  SER B C   1 
ATOM   216  O  O   . SER A 1 28  ? 17.808  -24.535 48.747  1.00 35.79  ? 28  SER B O   1 
ATOM   217  C  CB  . SER A 1 28  ? 17.346  -27.079 50.906  1.00 29.92  ? 28  SER B CB  1 
ATOM   218  O  OG  . SER A 1 28  ? 17.651  -26.031 51.793  1.00 36.11  ? 28  SER B OG  1 
ATOM   219  N  N   . TYR A 1 29  ? 18.809  -26.492 48.211  1.00 36.92  ? 29  TYR B N   1 
ATOM   220  C  CA  . TYR A 1 29  ? 19.891  -25.837 47.470  1.00 33.38  ? 29  TYR B CA  1 
ATOM   221  C  C   . TYR A 1 29  ? 19.361  -25.086 46.239  1.00 34.31  ? 29  TYR B C   1 
ATOM   222  O  O   . TYR A 1 29  ? 19.822  -23.982 45.932  1.00 31.27  ? 29  TYR B O   1 
ATOM   223  C  CB  . TYR A 1 29  ? 20.933  -26.884 47.066  1.00 32.54  ? 29  TYR B CB  1 
ATOM   224  C  CG  . TYR A 1 29  ? 22.346  -26.379 46.789  1.00 28.35  ? 29  TYR B CG  1 
ATOM   225  C  CD1 . TYR A 1 29  ? 22.771  -25.150 47.236  1.00 30.69  ? 29  TYR B CD1 1 
ATOM   226  C  CD2 . TYR A 1 29  ? 23.258  -27.176 46.105  1.00 31.00  ? 29  TYR B CD2 1 
ATOM   227  C  CE1 . TYR A 1 29  ? 24.053  -24.711 47.005  1.00 31.95  ? 29  TYR B CE1 1 
ATOM   228  C  CE2 . TYR A 1 29  ? 24.547  -26.763 45.871  1.00 30.45  ? 29  TYR B CE2 1 
ATOM   229  C  CZ  . TYR A 1 29  ? 24.943  -25.520 46.315  1.00 38.27  ? 29  TYR B CZ  1 
ATOM   230  O  OH  . TYR A 1 29  ? 26.235  -25.097 46.080  1.00 34.84  ? 29  TYR B OH  1 
ATOM   231  N  N   . VAL A 1 30  ? 18.406  -25.665 45.509  1.00 28.57  ? 30  VAL B N   1 
ATOM   232  C  CA  . VAL A 1 30  ? 17.825  -24.936 44.385  1.00 32.01  ? 30  VAL B CA  1 
ATOM   233  C  C   . VAL A 1 30  ? 17.245  -23.609 44.860  1.00 40.27  ? 30  VAL B C   1 
ATOM   234  O  O   . VAL A 1 30  ? 17.528  -22.546 44.291  1.00 36.96  ? 30  VAL B O   1 
ATOM   235  C  CB  . VAL A 1 30  ? 16.754  -25.780 43.681  1.00 36.58  ? 30  VAL B CB  1 
ATOM   236  C  CG1 . VAL A 1 30  ? 16.006  -24.916 42.646  1.00 37.20  ? 30  VAL B CG1 1 
ATOM   237  C  CG2 . VAL A 1 30  ? 17.369  -27.015 43.048  1.00 29.18  ? 30  VAL B CG2 1 
ATOM   238  N  N   . TYR A 1 31  ? 16.424  -23.653 45.919  1.00 37.53  ? 31  TYR B N   1 
ATOM   239  C  CA  . TYR A 1 31  ? 15.814  -22.431 46.431  1.00 36.80  ? 31  TYR B CA  1 
ATOM   240  C  C   . TYR A 1 31  ? 16.864  -21.437 46.924  1.00 36.24  ? 31  TYR B C   1 
ATOM   241  O  O   . TYR A 1 31  ? 16.658  -20.225 46.822  1.00 36.75  ? 31  TYR B O   1 
ATOM   242  C  CB  . TYR A 1 31  ? 14.824  -22.753 47.551  1.00 35.26  ? 31  TYR B CB  1 
ATOM   243  C  CG  . TYR A 1 31  ? 13.491  -23.299 47.086  1.00 33.13  ? 31  TYR B CG  1 
ATOM   244  C  CD1 . TYR A 1 31  ? 12.777  -22.676 46.075  1.00 41.35  ? 31  TYR B CD1 1 
ATOM   245  C  CD2 . TYR A 1 31  ? 12.942  -24.447 47.665  1.00 36.95  ? 31  TYR B CD2 1 
ATOM   246  C  CE1 . TYR A 1 31  ? 11.547  -23.174 45.644  1.00 39.77  ? 31  TYR B CE1 1 
ATOM   247  C  CE2 . TYR A 1 31  ? 11.731  -24.950 47.245  1.00 41.70  ? 31  TYR B CE2 1 
ATOM   248  C  CZ  . TYR A 1 31  ? 11.033  -24.301 46.235  1.00 45.38  ? 31  TYR B CZ  1 
ATOM   249  O  OH  . TYR A 1 31  ? 9.823   -24.782 45.810  1.00 46.70  ? 31  TYR B OH  1 
ATOM   250  N  N   . LEU A 1 32  ? 17.997  -21.915 47.442  1.00 31.63  ? 32  LEU B N   1 
ATOM   251  C  CA  . LEU A 1 32  ? 19.057  -20.989 47.825  1.00 33.75  ? 32  LEU B CA  1 
ATOM   252  C  C   . LEU A 1 32  ? 19.623  -20.258 46.602  1.00 38.00  ? 32  LEU B C   1 
ATOM   253  O  O   . LEU A 1 32  ? 19.860  -19.039 46.642  1.00 31.92  ? 32  LEU B O   1 
ATOM   254  C  CB  . LEU A 1 32  ? 20.161  -21.741 48.570  1.00 33.91  ? 32  LEU B CB  1 
ATOM   255  C  CG  . LEU A 1 32  ? 21.141  -20.816 49.288  1.00 39.21  ? 32  LEU B CG  1 
ATOM   256  C  CD1 . LEU A 1 32  ? 20.441  -20.241 50.485  1.00 37.14  ? 32  LEU B CD1 1 
ATOM   257  C  CD2 . LEU A 1 32  ? 22.409  -21.541 49.691  1.00 37.80  ? 32  LEU B CD2 1 
ATOM   258  N  N   . SER A 1 33  ? 19.839  -20.993 45.508  1.00 33.61  ? 33  SER B N   1 
ATOM   259  C  CA  . SER A 1 33  ? 20.275  -20.390 44.255  1.00 30.70  ? 33  SER B CA  1 
ATOM   260  C  C   . SER A 1 33  ? 19.296  -19.322 43.782  1.00 33.22  ? 33  SER B C   1 
ATOM   261  O  O   . SER A 1 33  ? 19.697  -18.203 43.437  1.00 34.90  ? 33  SER B O   1 
ATOM   262  C  CB  . SER A 1 33  ? 20.426  -21.485 43.198  1.00 34.69  ? 33  SER B CB  1 
ATOM   263  O  OG  . SER A 1 33  ? 20.612  -20.922 41.914  1.00 36.88  ? 33  SER B OG  1 
ATOM   264  N  N   . MET A 1 34  ? 18.006  -19.668 43.735  1.00 31.96  ? 34  MET B N   1 
ATOM   265  C  CA  . MET A 1 34  ? 16.967  -18.715 43.358  1.00 34.99  ? 34  MET B CA  1 
ATOM   266  C  C   . MET A 1 34  ? 17.012  -17.477 44.232  1.00 37.64  ? 34  MET B C   1 
ATOM   267  O  O   . MET A 1 34  ? 16.976  -16.346 43.734  1.00 37.47  ? 34  MET B O   1 
ATOM   268  C  CB  . MET A 1 34  ? 15.590  -19.372 43.472  1.00 33.95  ? 34  MET B CB  1 
ATOM   269  C  CG  . MET A 1 34  ? 15.294  -20.341 42.357  1.00 37.96  ? 34  MET B CG  1 
ATOM   270  S  SD  . MET A 1 34  ? 13.640  -21.012 42.487  1.00 41.10  ? 34  MET B SD  1 
ATOM   271  C  CE  . MET A 1 34  ? 13.751  -22.294 41.238  1.00 34.91  ? 34  MET B CE  1 
ATOM   272  N  N   . ALA A 1 35  ? 17.070  -17.675 45.550  1.00 35.84  ? 35  ALA B N   1 
ATOM   273  C  CA  . ALA A 1 35  ? 16.888  -16.554 46.462  1.00 36.53  ? 35  ALA B CA  1 
ATOM   274  C  C   . ALA A 1 35  ? 17.934  -15.482 46.217  1.00 40.37  ? 35  ALA B C   1 
ATOM   275  O  O   . ALA A 1 35  ? 17.599  -14.295 46.168  1.00 42.34  ? 35  ALA B O   1 
ATOM   276  C  CB  . ALA A 1 35  ? 16.939  -17.033 47.912  1.00 34.63  ? 35  ALA B CB  1 
ATOM   277  N  N   . TYR A 1 36  ? 19.202  -15.884 46.031  1.00 37.25  ? 36  TYR B N   1 
ATOM   278  C  CA  . TYR A 1 36  ? 20.299  -14.938 45.845  1.00 39.00  ? 36  TYR B CA  1 
ATOM   279  C  C   . TYR A 1 36  ? 20.433  -14.483 44.404  1.00 37.74  ? 36  TYR B C   1 
ATOM   280  O  O   . TYR A 1 36  ? 21.106  -13.482 44.141  1.00 35.78  ? 36  TYR B O   1 
ATOM   281  C  CB  . TYR A 1 36  ? 21.634  -15.535 46.351  1.00 35.36  ? 36  TYR B CB  1 
ATOM   282  C  CG  . TYR A 1 36  ? 21.678  -15.456 47.850  1.00 45.03  ? 36  TYR B CG  1 
ATOM   283  C  CD1 . TYR A 1 36  ? 21.087  -16.444 48.638  1.00 37.53  ? 36  TYR B CD1 1 
ATOM   284  C  CD2 . TYR A 1 36  ? 22.206  -14.335 48.487  1.00 43.95  ? 36  TYR B CD2 1 
ATOM   285  C  CE1 . TYR A 1 36  ? 21.077  -16.341 50.030  1.00 43.22  ? 36  TYR B CE1 1 
ATOM   286  C  CE2 . TYR A 1 36  ? 22.194  -14.220 49.871  1.00 46.59  ? 36  TYR B CE2 1 
ATOM   287  C  CZ  . TYR A 1 36  ? 21.629  -15.222 50.645  1.00 52.06  ? 36  TYR B CZ  1 
ATOM   288  O  OH  . TYR A 1 36  ? 21.628  -15.098 52.032  1.00 48.32  ? 36  TYR B OH  1 
ATOM   289  N  N   . TYR A 1 37  ? 19.812  -15.194 43.467  1.00 34.65  ? 37  TYR B N   1 
ATOM   290  C  CA  . TYR A 1 37  ? 19.704  -14.667 42.119  1.00 35.40  ? 37  TYR B CA  1 
ATOM   291  C  C   . TYR A 1 37  ? 18.876  -13.389 42.133  1.00 40.39  ? 37  TYR B C   1 
ATOM   292  O  O   . TYR A 1 37  ? 19.231  -12.392 41.491  1.00 37.31  ? 37  TYR B O   1 
ATOM   293  C  CB  . TYR A 1 37  ? 19.086  -15.728 41.212  1.00 33.58  ? 37  TYR B CB  1 
ATOM   294  C  CG  . TYR A 1 37  ? 18.782  -15.277 39.804  1.00 37.34  ? 37  TYR B CG  1 
ATOM   295  C  CD1 . TYR A 1 37  ? 19.761  -15.325 38.805  1.00 37.39  ? 37  TYR B CD1 1 
ATOM   296  C  CD2 . TYR A 1 37  ? 17.510  -14.825 39.463  1.00 40.13  ? 37  TYR B CD2 1 
ATOM   297  C  CE1 . TYR A 1 37  ? 19.482  -14.917 37.515  1.00 40.84  ? 37  TYR B CE1 1 
ATOM   298  C  CE2 . TYR A 1 37  ? 17.217  -14.409 38.169  1.00 38.84  ? 37  TYR B CE2 1 
ATOM   299  C  CZ  . TYR A 1 37  ? 18.198  -14.466 37.206  1.00 44.84  ? 37  TYR B CZ  1 
ATOM   300  O  OH  . TYR A 1 37  ? 17.889  -14.060 35.935  1.00 50.10  ? 37  TYR B OH  1 
ATOM   301  N  N   . PHE A 1 38  ? 17.797  -13.384 42.911  1.00 33.74  ? 38  PHE B N   1 
ATOM   302  C  CA  . PHE A 1 38  ? 16.910  -12.240 42.929  1.00 39.40  ? 38  PHE B CA  1 
ATOM   303  C  C   . PHE A 1 38  ? 17.430  -11.122 43.811  1.00 37.37  ? 38  PHE B C   1 
ATOM   304  O  O   . PHE A 1 38  ? 16.782  -10.085 43.905  1.00 35.36  ? 38  PHE B O   1 
ATOM   305  C  CB  . PHE A 1 38  ? 15.509  -12.687 43.337  1.00 37.50  ? 38  PHE B CB  1 
ATOM   306  C  CG  . PHE A 1 38  ? 14.817  -13.465 42.259  1.00 37.53  ? 38  PHE B CG  1 
ATOM   307  C  CD1 . PHE A 1 38  ? 14.333  -12.823 41.136  1.00 33.05  ? 38  PHE B CD1 1 
ATOM   308  C  CD2 . PHE A 1 38  ? 14.697  -14.837 42.340  1.00 41.60  ? 38  PHE B CD2 1 
ATOM   309  C  CE1 . PHE A 1 38  ? 13.720  -13.531 40.123  1.00 39.11  ? 38  PHE B CE1 1 
ATOM   310  C  CE2 . PHE A 1 38  ? 14.077  -15.558 41.324  1.00 38.88  ? 38  PHE B CE2 1 
ATOM   311  C  CZ  . PHE A 1 38  ? 13.588  -14.897 40.216  1.00 40.52  ? 38  PHE B CZ  1 
ATOM   312  N  N   . GLU A 1 39  ? 18.598  -11.299 44.423  1.00 39.70  ? 39  GLU B N   1 
ATOM   313  C  CA  . GLU A 1 39  ? 19.322  -10.211 45.060  1.00 39.80  ? 39  GLU B CA  1 
ATOM   314  C  C   . GLU A 1 39  ? 20.451  -9.683  44.185  1.00 37.72  ? 39  GLU B C   1 
ATOM   315  O  O   . GLU A 1 39  ? 21.229  -8.836  44.637  1.00 39.46  ? 39  GLU B O   1 
ATOM   316  C  CB  . GLU A 1 39  ? 19.880  -10.663 46.418  1.00 38.08  ? 39  GLU B CB  1 
ATOM   317  C  CG  . GLU A 1 39  ? 18.811  -10.904 47.454  1.00 30.90  ? 39  GLU B CG  1 
ATOM   318  C  CD  . GLU A 1 39  ? 19.377  -11.132 48.845  1.00 41.06  ? 39  GLU B CD  1 
ATOM   319  O  OE1 . GLU A 1 39  ? 20.597  -10.974 49.038  1.00 50.99  ? 39  GLU B OE1 1 
ATOM   320  O  OE2 . GLU A 1 39  ? 18.593  -11.468 49.751  1.00 53.92  ? 39  GLU B OE2 1 
ATOM   321  N  N   . ARG A 1 40  ? 20.567  -10.157 42.947  1.00 38.99  ? 40  ARG B N   1 
ATOM   322  C  CA  . ARG A 1 40  ? 21.556  -9.586  42.047  1.00 40.84  ? 40  ARG B CA  1 
ATOM   323  C  C   . ARG A 1 40  ? 21.218  -8.123  41.762  1.00 43.43  ? 40  ARG B C   1 
ATOM   324  O  O   . ARG A 1 40  ? 20.049  -7.746  41.649  1.00 39.01  ? 40  ARG B O   1 
ATOM   325  C  CB  . ARG A 1 40  ? 21.611  -10.406 40.766  1.00 39.94  ? 40  ARG B CB  1 
ATOM   326  C  CG  . ARG A 1 40  ? 22.635  -11.506 40.813  1.00 45.41  ? 40  ARG B CG  1 
ATOM   327  C  CD  . ARG A 1 40  ? 22.295  -12.662 39.881  1.00 50.94  ? 40  ARG B CD  1 
ATOM   328  N  NE  . ARG A 1 40  ? 22.146  -12.242 38.491  1.00 59.28  ? 40  ARG B NE  1 
ATOM   329  C  CZ  . ARG A 1 40  ? 22.454  -12.989 37.418  1.00 69.36  ? 40  ARG B CZ  1 
ATOM   330  N  NH1 . ARG A 1 40  ? 22.980  -14.212 37.561  1.00 57.94  ? 40  ARG B NH1 1 
ATOM   331  N  NH2 . ARG A 1 40  ? 22.252  -12.492 36.188  1.00 61.92  ? 40  ARG B NH2 1 
ATOM   332  N  N   . ASP A 1 41  ? 22.250  -7.285  41.676  1.00 49.03  ? 41  ASP B N   1 
ATOM   333  C  CA  . ASP A 1 41  ? 22.025  -5.866  41.425  1.00 52.26  ? 41  ASP B CA  1 
ATOM   334  C  C   . ASP A 1 41  ? 21.322  -5.609  40.090  1.00 47.04  ? 41  ASP B C   1 
ATOM   335  O  O   . ASP A 1 41  ? 20.745  -4.534  39.904  1.00 50.73  ? 41  ASP B O   1 
ATOM   336  C  CB  . ASP A 1 41  ? 23.349  -5.115  41.456  1.00 48.96  ? 41  ASP B CB  1 
ATOM   337  C  CG  . ASP A 1 41  ? 24.268  -5.546  40.329  1.00 58.97  ? 41  ASP B CG  1 
ATOM   338  O  OD1 . ASP A 1 41  ? 24.271  -4.847  39.298  1.00 64.06  ? 41  ASP B OD1 1 
ATOM   339  O  OD2 . ASP A 1 41  ? 24.965  -6.579  40.463  1.00 60.27  ? 41  ASP B OD2 1 
ATOM   340  N  N   . ASP A 1 42  ? 21.360  -6.551  39.156  1.00 42.46  ? 42  ASP B N   1 
ATOM   341  C  CA  . ASP A 1 42  ? 20.613  -6.423  37.911  1.00 44.44  ? 42  ASP B CA  1 
ATOM   342  C  C   . ASP A 1 42  ? 19.276  -7.155  37.955  1.00 41.73  ? 42  ASP B C   1 
ATOM   343  O  O   . ASP A 1 42  ? 18.633  -7.316  36.912  1.00 37.63  ? 42  ASP B O   1 
ATOM   344  C  CB  . ASP A 1 42  ? 21.441  -6.928  36.723  1.00 39.76  ? 42  ASP B CB  1 
ATOM   345  C  CG  . ASP A 1 42  ? 21.902  -8.352  36.907  1.00 51.41  ? 42  ASP B CG  1 
ATOM   346  O  OD1 . ASP A 1 42  ? 21.630  -8.920  37.989  1.00 51.19  ? 42  ASP B OD1 1 
ATOM   347  O  OD2 . ASP A 1 42  ? 22.545  -8.903  35.988  1.00 56.76  ? 42  ASP B OD2 1 
ATOM   348  N  N   . VAL A 1 43  ? 18.842  -7.609  39.128  1.00 37.25  ? 43  VAL B N   1 
ATOM   349  C  CA  . VAL A 1 43  ? 17.540  -8.252  39.216  1.00 41.38  ? 43  VAL B CA  1 
ATOM   350  C  C   . VAL A 1 43  ? 16.722  -7.542  40.284  1.00 38.76  ? 43  VAL B C   1 
ATOM   351  O  O   . VAL A 1 43  ? 15.600  -7.097  40.016  1.00 39.50  ? 43  VAL B O   1 
ATOM   352  C  CB  . VAL A 1 43  ? 17.669  -9.765  39.493  1.00 41.45  ? 43  VAL B CB  1 
ATOM   353  C  CG1 . VAL A 1 43  ? 16.308  -10.396 39.555  1.00 35.97  ? 43  VAL B CG1 1 
ATOM   354  C  CG2 . VAL A 1 43  ? 18.496  -10.442 38.416  1.00 33.54  ? 43  VAL B CG2 1 
ATOM   355  N  N   . CYS A 1 44  ? 17.293  -7.417  41.489  1.00 42.58  ? 44  CYS B N   1 
ATOM   356  C  CA  . CYS A 1 44  ? 16.683  -6.751  42.646  1.00 42.86  ? 44  CYS B CA  1 
ATOM   357  C  C   . CYS A 1 44  ? 15.183  -6.969  42.776  1.00 39.23  ? 44  CYS B C   1 
ATOM   358  O  O   . CYS A 1 44  ? 14.393  -6.032  42.608  1.00 40.67  ? 44  CYS B O   1 
ATOM   359  C  CB  . CYS A 1 44  ? 16.946  -5.235  42.640  1.00 43.17  ? 44  CYS B CB  1 
ATOM   360  S  SG  . CYS A 1 44  ? 18.617  -4.724  42.101  1.00 69.38  ? 44  CYS B SG  1 
ATOM   361  N  N   . LEU A 1 45  ? 14.781  -8.191  43.098  1.00 34.20  ? 45  LEU B N   1 
ATOM   362  C  CA  . LEU A 1 45  ? 13.387  -8.513  43.381  1.00 42.06  ? 45  LEU B CA  1 
ATOM   363  C  C   . LEU A 1 45  ? 13.353  -9.090  44.798  1.00 40.13  ? 45  LEU B C   1 
ATOM   364  O  O   . LEU A 1 45  ? 13.379  -10.314 44.984  1.00 42.14  ? 45  LEU B O   1 
ATOM   365  C  CB  . LEU A 1 45  ? 12.823  -9.463  42.324  1.00 34.16  ? 45  LEU B CB  1 
ATOM   366  C  CG  . LEU A 1 45  ? 12.469  -8.823  40.977  1.00 39.46  ? 45  LEU B CG  1 
ATOM   367  C  CD1 . LEU A 1 45  ? 12.145  -9.879  39.891  1.00 34.36  ? 45  LEU B CD1 1 
ATOM   368  C  CD2 . LEU A 1 45  ? 11.310  -7.834  41.126  1.00 32.42  ? 45  LEU B CD2 1 
ATOM   369  N  N   . PRO A 1 46  ? 13.309  -8.230  45.824  1.00 43.74  ? 46  PRO B N   1 
ATOM   370  C  CA  . PRO A 1 46  ? 13.425  -8.725  47.212  1.00 40.93  ? 46  PRO B CA  1 
ATOM   371  C  C   . PRO A 1 46  ? 12.254  -9.562  47.675  1.00 38.24  ? 46  PRO B C   1 
ATOM   372  O  O   . PRO A 1 46  ? 12.424  -10.368 48.594  1.00 43.18  ? 46  PRO B O   1 
ATOM   373  C  CB  . PRO A 1 46  ? 13.534  -7.433  48.037  1.00 37.44  ? 46  PRO B CB  1 
ATOM   374  C  CG  . PRO A 1 46  ? 12.834  -6.416  47.211  1.00 37.48  ? 46  PRO B CG  1 
ATOM   375  C  CD  . PRO A 1 46  ? 13.186  -6.763  45.781  1.00 36.37  ? 46  PRO B CD  1 
ATOM   376  N  N   . GLY A 1 47  ? 11.067  -9.391  47.095  1.00 44.61  ? 47  GLY B N   1 
ATOM   377  C  CA  . GLY A 1 47  ? 9.957   -10.257 47.452  1.00 41.52  ? 47  GLY B CA  1 
ATOM   378  C  C   . GLY A 1 47  ? 10.188  -11.684 46.996  1.00 40.87  ? 47  GLY B C   1 
ATOM   379  O  O   . GLY A 1 47  ? 10.026  -12.634 47.773  1.00 42.07  ? 47  GLY B O   1 
ATOM   380  N  N   . PHE A 1 48  ? 10.562  -11.859 45.728  1.00 37.17  ? 48  PHE B N   1 
ATOM   381  C  CA  . PHE A 1 48  ? 10.956  -13.187 45.277  1.00 37.13  ? 48  PHE B CA  1 
ATOM   382  C  C   . PHE A 1 48  ? 12.093  -13.714 46.131  1.00 37.69  ? 48  PHE B C   1 
ATOM   383  O  O   . PHE A 1 48  ? 12.090  -14.890 46.518  1.00 33.60  ? 48  PHE B O   1 
ATOM   384  C  CB  . PHE A 1 48  ? 11.366  -13.156 43.810  1.00 38.90  ? 48  PHE B CB  1 
ATOM   385  C  CG  . PHE A 1 48  ? 10.219  -13.034 42.874  1.00 34.90  ? 48  PHE B CG  1 
ATOM   386  C  CD1 . PHE A 1 48  ? 9.608   -14.165 42.368  1.00 41.73  ? 48  PHE B CD1 1 
ATOM   387  C  CD2 . PHE A 1 48  ? 9.757   -11.794 42.488  1.00 34.87  ? 48  PHE B CD2 1 
ATOM   388  C  CE1 . PHE A 1 48  ? 8.549   -14.065 41.498  1.00 41.19  ? 48  PHE B CE1 1 
ATOM   389  C  CE2 . PHE A 1 48  ? 8.690   -11.679 41.624  1.00 39.85  ? 48  PHE B CE2 1 
ATOM   390  C  CZ  . PHE A 1 48  ? 8.085   -12.818 41.126  1.00 43.45  ? 48  PHE B CZ  1 
ATOM   391  N  N   . ALA A 1 49  ? 13.039  -12.839 46.495  1.00 28.83  ? 49  ALA B N   1 
ATOM   392  C  CA  . ALA A 1 49  ? 14.233  -13.316 47.181  1.00 35.74  ? 49  ALA B CA  1 
ATOM   393  C  C   . ALA A 1 49  ? 13.898  -13.830 48.575  1.00 36.68  ? 49  ALA B C   1 
ATOM   394  O  O   . ALA A 1 49  ? 14.351  -14.914 48.971  1.00 39.64  ? 49  ALA B O   1 
ATOM   395  C  CB  . ALA A 1 49  ? 15.301  -12.222 47.234  1.00 31.99  ? 49  ALA B CB  1 
ATOM   396  N  N   . LYS A 1 50  ? 13.088  -13.077 49.329  1.00 36.43  ? 50  LYS B N   1 
ATOM   397  C  CA  . LYS A 1 50  ? 12.660  -13.542 50.651  1.00 39.01  ? 50  LYS B CA  1 
ATOM   398  C  C   . LYS A 1 50  ? 11.854  -14.834 50.544  1.00 39.74  ? 50  LYS B C   1 
ATOM   399  O  O   . LYS A 1 50  ? 12.061  -15.770 51.327  1.00 38.08  ? 50  LYS B O   1 
ATOM   400  C  CB  . LYS A 1 50  ? 11.861  -12.440 51.358  1.00 37.29  ? 50  LYS B CB  1 
ATOM   401  C  CG  . LYS A 1 50  ? 11.119  -12.848 52.627  1.00 46.76  ? 50  LYS B CG  1 
ATOM   402  C  CD  . LYS A 1 50  ? 10.491  -11.613 53.306  1.00 53.84  ? 50  LYS B CD  1 
ATOM   403  C  CE  . LYS A 1 50  ? 10.003  -11.905 54.737  1.00 63.89  ? 50  LYS B CE  1 
ATOM   404  N  NZ  . LYS A 1 50  ? 8.679   -12.612 54.801  1.00 67.59  ? 50  LYS B NZ  1 
ATOM   405  N  N   . PHE A 1 51  ? 10.965  -14.921 49.549  1.00 33.26  ? 51  PHE B N   1 
ATOM   406  C  CA  . PHE A 1 51  ? 10.140  -16.112 49.395  1.00 32.45  ? 51  PHE B CA  1 
ATOM   407  C  C   . PHE A 1 51  ? 10.998  -17.356 49.236  1.00 43.83  ? 51  PHE B C   1 
ATOM   408  O  O   . PHE A 1 51  ? 10.842  -18.334 49.984  1.00 43.12  ? 51  PHE B O   1 
ATOM   409  C  CB  . PHE A 1 51  ? 9.219   -15.949 48.196  1.00 35.33  ? 51  PHE B CB  1 
ATOM   410  C  CG  . PHE A 1 51  ? 8.347   -17.148 47.927  1.00 33.42  ? 51  PHE B CG  1 
ATOM   411  C  CD1 . PHE A 1 51  ? 7.249   -17.414 48.724  1.00 30.59  ? 51  PHE B CD1 1 
ATOM   412  C  CD2 . PHE A 1 51  ? 8.611   -17.990 46.851  1.00 32.45  ? 51  PHE B CD2 1 
ATOM   413  C  CE1 . PHE A 1 51  ? 6.432   -18.527 48.461  1.00 40.70  ? 51  PHE B CE1 1 
ATOM   414  C  CE2 . PHE A 1 51  ? 7.798   -19.098 46.580  1.00 34.19  ? 51  PHE B CE2 1 
ATOM   415  C  CZ  . PHE A 1 51  ? 6.716   -19.369 47.384  1.00 32.31  ? 51  PHE B CZ  1 
ATOM   416  N  N   . PHE A 1 52  ? 11.927  -17.322 48.269  1.00 36.08  ? 52  PHE B N   1 
ATOM   417  C  CA  . PHE A 1 52  ? 12.799  -18.458 48.012  1.00 34.90  ? 52  PHE B CA  1 
ATOM   418  C  C   . PHE A 1 52  ? 13.767  -18.716 49.164  1.00 35.46  ? 52  PHE B C   1 
ATOM   419  O  O   . PHE A 1 52  ? 14.082  -19.877 49.457  1.00 38.62  ? 52  PHE B O   1 
ATOM   420  C  CB  . PHE A 1 52  ? 13.538  -18.234 46.696  1.00 31.10  ? 52  PHE B CB  1 
ATOM   421  C  CG  . PHE A 1 52  ? 12.633  -18.285 45.500  1.00 35.49  ? 52  PHE B CG  1 
ATOM   422  C  CD1 . PHE A 1 52  ? 11.811  -19.379 45.293  1.00 31.41  ? 52  PHE B CD1 1 
ATOM   423  C  CD2 . PHE A 1 52  ? 12.609  -17.252 44.585  1.00 35.81  ? 52  PHE B CD2 1 
ATOM   424  C  CE1 . PHE A 1 52  ? 10.978  -19.435 44.228  1.00 30.68  ? 52  PHE B CE1 1 
ATOM   425  C  CE2 . PHE A 1 52  ? 11.769  -17.304 43.497  1.00 32.60  ? 52  PHE B CE2 1 
ATOM   426  C  CZ  . PHE A 1 52  ? 10.950  -18.398 43.325  1.00 38.11  ? 52  PHE B CZ  1 
ATOM   427  N  N   . LYS A 1 53  ? 14.237  -17.672 49.843  1.00 40.47  ? 53  LYS B N   1 
ATOM   428  C  CA  . LYS A 1 53  ? 15.047  -17.900 51.040  1.00 43.78  ? 53  LYS B CA  1 
ATOM   429  C  C   . LYS A 1 53  ? 14.248  -18.660 52.094  1.00 40.08  ? 53  LYS B C   1 
ATOM   430  O  O   . LYS A 1 53  ? 14.792  -19.519 52.796  1.00 46.18  ? 53  LYS B O   1 
ATOM   431  C  CB  . LYS A 1 53  ? 15.573  -16.572 51.598  1.00 33.23  ? 53  LYS B CB  1 
ATOM   432  C  CG  . LYS A 1 53  ? 16.924  -16.672 52.227  1.00 42.75  ? 53  LYS B CG  1 
ATOM   433  C  CD  . LYS A 1 53  ? 17.518  -15.291 52.573  1.00 55.11  ? 53  LYS B CD  1 
ATOM   434  C  CE  . LYS A 1 53  ? 17.585  -14.317 51.380  1.00 55.93  ? 53  LYS B CE  1 
ATOM   435  N  NZ  . LYS A 1 53  ? 18.250  -13.029 51.777  1.00 51.96  ? 53  LYS B NZ  1 
ATOM   436  N  N   . GLU A 1 54  ? 12.942  -18.394 52.192  1.00 42.45  ? 54  GLU B N   1 
ATOM   437  C  CA  . GLU A 1 54  ? 12.127  -19.124 53.162  1.00 45.79  ? 54  GLU B CA  1 
ATOM   438  C  C   . GLU A 1 54  ? 11.814  -20.536 52.678  1.00 43.32  ? 54  GLU B C   1 
ATOM   439  O  O   . GLU A 1 54  ? 11.846  -21.483 53.475  1.00 38.03  ? 54  GLU B O   1 
ATOM   440  C  CB  . GLU A 1 54  ? 10.845  -18.344 53.477  1.00 39.32  ? 54  GLU B CB  1 
ATOM   441  C  CG  . GLU A 1 54  ? 11.136  -17.046 54.213  1.00 41.23  ? 54  GLU B CG  1 
ATOM   442  C  CD  . GLU A 1 54  ? 9.898   -16.225 54.578  1.00 60.52  ? 54  GLU B CD  1 
ATOM   443  O  OE1 . GLU A 1 54  ? 8.822   -16.425 53.954  1.00 59.38  ? 54  GLU B OE1 1 
ATOM   444  O  OE2 . GLU A 1 54  ? 10.025  -15.365 55.491  1.00 61.66  ? 54  GLU B OE2 1 
ATOM   445  N  N   . SER A 1 55  ? 11.539  -20.706 51.377  1.00 36.60  ? 55  SER B N   1 
ATOM   446  C  CA  . SER A 1 55  ? 11.416  -22.057 50.853  1.00 37.98  ? 55  SER B CA  1 
ATOM   447  C  C   . SER A 1 55  ? 12.703  -22.852 51.059  1.00 43.59  ? 55  SER B C   1 
ATOM   448  O  O   . SER A 1 55  ? 12.652  -24.064 51.311  1.00 38.70  ? 55  SER B O   1 
ATOM   449  C  CB  . SER A 1 55  ? 11.042  -22.025 49.376  1.00 33.33  ? 55  SER B CB  1 
ATOM   450  O  OG  . SER A 1 55  ? 9.787   -21.397 49.207  1.00 47.96  ? 55  SER B OG  1 
ATOM   451  N  N   . SER A 1 56  ? 13.863  -22.195 50.984  1.00 37.51  ? 56  SER B N   1 
ATOM   452  C  CA  . SER A 1 56  ? 15.106  -22.938 51.147  1.00 40.11  ? 56  SER B CA  1 
ATOM   453  C  C   . SER A 1 56  ? 15.233  -23.471 52.567  1.00 38.22  ? 56  SER B C   1 
ATOM   454  O  O   . SER A 1 56  ? 15.587  -24.636 52.762  1.00 39.64  ? 56  SER B O   1 
ATOM   455  C  CB  . SER A 1 56  ? 16.312  -22.077 50.776  1.00 34.62  ? 56  SER B CB  1 
ATOM   456  O  OG  . SER A 1 56  ? 17.521  -22.718 51.145  1.00 32.70  ? 56  SER B OG  1 
ATOM   457  N  N   . ASP A 1 57  ? 14.922  -22.642 53.570  1.00 38.42  ? 57  ASP B N   1 
ATOM   458  C  CA  . ASP A 1 57  ? 14.968  -23.107 54.958  1.00 40.17  ? 57  ASP B CA  1 
ATOM   459  C  C   . ASP A 1 57  ? 13.917  -24.176 55.212  1.00 40.10  ? 57  ASP B C   1 
ATOM   460  O  O   . ASP A 1 57  ? 14.177  -25.167 55.901  1.00 43.71  ? 57  ASP B O   1 
ATOM   461  C  CB  . ASP A 1 57  ? 14.750  -21.943 55.922  1.00 35.97  ? 57  ASP B CB  1 
ATOM   462  C  CG  . ASP A 1 57  ? 15.829  -20.879 55.813  1.00 46.01  ? 57  ASP B CG  1 
ATOM   463  O  OD1 . ASP A 1 57  ? 16.968  -21.215 55.433  1.00 49.73  ? 57  ASP B OD1 1 
ATOM   464  O  OD2 . ASP A 1 57  ? 15.532  -19.697 56.095  1.00 46.44  ? 57  ASP B OD2 1 
ATOM   465  N  N   . GLU A 1 58  ? 12.715  -23.975 54.679  1.00 42.79  ? 58  GLU B N   1 
ATOM   466  C  CA  . GLU A 1 58  ? 11.647  -24.955 54.815  1.00 43.14  ? 58  GLU B CA  1 
ATOM   467  C  C   . GLU A 1 58  ? 12.121  -26.333 54.352  1.00 50.96  ? 58  GLU B C   1 
ATOM   468  O  O   . GLU A 1 58  ? 11.990  -27.323 55.084  1.00 44.30  ? 58  GLU B O   1 
ATOM   469  C  CB  . GLU A 1 58  ? 10.434  -24.469 54.010  1.00 43.90  ? 58  GLU B CB  1 
ATOM   470  C  CG  . GLU A 1 58  ? 9.026   -24.869 54.483  1.00 62.65  ? 58  GLU B CG  1 
ATOM   471  C  CD  . GLU A 1 58  ? 7.913   -24.094 53.733  1.00 78.75  ? 58  GLU B CD  1 
ATOM   472  O  OE1 . GLU A 1 58  ? 6.978   -24.735 53.186  1.00 78.34  ? 58  GLU B OE1 1 
ATOM   473  O  OE2 . GLU A 1 58  ? 7.984   -22.838 53.685  1.00 71.22  ? 58  GLU B OE2 1 
ATOM   474  N  N   . GLU A 1 59  ? 12.721  -26.403 53.148  1.00 43.27  ? 59  GLU B N   1 
ATOM   475  C  CA  . GLU A 1 59  ? 13.179  -27.687 52.624  1.00 43.51  ? 59  GLU B CA  1 
ATOM   476  C  C   . GLU A 1 59  ? 14.252  -28.301 53.515  1.00 43.29  ? 59  GLU B C   1 
ATOM   477  O  O   . GLU A 1 59  ? 14.237  -29.512 53.769  1.00 42.36  ? 59  GLU B O   1 
ATOM   478  C  CB  . GLU A 1 59  ? 13.711  -27.539 51.197  1.00 38.12  ? 59  GLU B CB  1 
ATOM   479  C  CG  . GLU A 1 59  ? 12.664  -27.199 50.183  1.00 42.31  ? 59  GLU B CG  1 
ATOM   480  C  CD  . GLU A 1 59  ? 11.463  -28.090 50.313  1.00 56.21  ? 59  GLU B CD  1 
ATOM   481  O  OE1 . GLU A 1 59  ? 11.592  -29.288 49.987  1.00 53.97  ? 59  GLU B OE1 1 
ATOM   482  O  OE2 . GLU A 1 59  ? 10.405  -27.596 50.776  1.00 60.40  ? 59  GLU B OE2 1 
ATOM   483  N  N   . ARG A 1 60  ? 15.201  -27.484 53.979  1.00 35.30  ? 60  ARG B N   1 
ATOM   484  C  CA  . ARG A 1 60  ? 16.239  -27.974 54.877  1.00 42.09  ? 60  ARG B CA  1 
ATOM   485  C  C   . ARG A 1 60  ? 15.633  -28.565 56.144  1.00 44.43  ? 60  ARG B C   1 
ATOM   486  O  O   . ARG A 1 60  ? 16.101  -29.603 56.632  1.00 43.37  ? 60  ARG B O   1 
ATOM   487  C  CB  . ARG A 1 60  ? 17.218  -26.841 55.213  1.00 35.89  ? 60  ARG B CB  1 
ATOM   488  C  CG  . ARG A 1 60  ? 18.427  -27.272 56.005  1.00 35.21  ? 60  ARG B CG  1 
ATOM   489  C  CD  . ARG A 1 60  ? 19.456  -26.169 55.991  1.00 48.69  ? 60  ARG B CD  1 
ATOM   490  N  NE  . ARG A 1 60  ? 20.647  -26.490 56.774  1.00 51.15  ? 60  ARG B NE  1 
ATOM   491  C  CZ  . ARG A 1 60  ? 20.771  -26.218 58.075  1.00 60.27  ? 60  ARG B CZ  1 
ATOM   492  N  NH1 . ARG A 1 60  ? 21.896  -26.523 58.736  1.00 51.56  ? 60  ARG B NH1 1 
ATOM   493  N  NH2 . ARG A 1 60  ? 19.760  -25.633 58.720  1.00 55.33  ? 60  ARG B NH2 1 
ATOM   494  N  N   . GLU A 1 61  ? 14.569  -27.933 56.669  1.00 42.82  ? 61  GLU B N   1 
ATOM   495  C  CA  . GLU A 1 61  ? 13.852  -28.466 57.829  1.00 48.04  ? 61  GLU B CA  1 
ATOM   496  C  C   . GLU A 1 61  ? 13.176  -29.792 57.509  1.00 41.75  ? 61  GLU B C   1 
ATOM   497  O  O   . GLU A 1 61  ? 13.265  -30.745 58.291  1.00 42.82  ? 61  GLU B O   1 
ATOM   498  C  CB  . GLU A 1 61  ? 12.820  -27.453 58.332  1.00 43.48  ? 61  GLU B CB  1 
ATOM   499  C  CG  . GLU A 1 61  ? 13.427  -26.235 59.014  1.00 51.50  ? 61  GLU B CG  1 
ATOM   500  C  CD  . GLU A 1 61  ? 14.194  -26.577 60.299  1.00 65.96  ? 61  GLU B CD  1 
ATOM   501  O  OE1 . GLU A 1 61  ? 13.988  -27.683 60.864  1.00 64.26  ? 61  GLU B OE1 1 
ATOM   502  O  OE2 . GLU A 1 61  ? 15.008  -25.731 60.739  1.00 68.40  ? 61  GLU B OE2 1 
ATOM   503  N  N   . HIS A 1 62  ? 12.480  -29.866 56.372  1.00 41.82  ? 62  HIS B N   1 
ATOM   504  C  CA  . HIS A 1 62  ? 11.915  -31.134 55.922  1.00 47.43  ? 62  HIS B CA  1 
ATOM   505  C  C   . HIS A 1 62  ? 12.967  -32.241 55.947  1.00 48.98  ? 62  HIS B C   1 
ATOM   506  O  O   . HIS A 1 62  ? 12.725  -33.329 56.482  1.00 48.67  ? 62  HIS B O   1 
ATOM   507  C  CB  . HIS A 1 62  ? 11.335  -30.982 54.515  1.00 52.82  ? 62  HIS B CB  1 
ATOM   508  C  CG  . HIS A 1 62  ? 9.994   -30.310 54.471  1.00 62.76  ? 62  HIS B CG  1 
ATOM   509  N  ND1 . HIS A 1 62  ? 9.023   -30.512 55.428  1.00 72.40  ? 62  HIS B ND1 1 
ATOM   510  C  CD2 . HIS A 1 62  ? 9.463   -29.438 53.578  1.00 66.03  ? 62  HIS B CD2 1 
ATOM   511  C  CE1 . HIS A 1 62  ? 7.955   -29.791 55.129  1.00 75.74  ? 62  HIS B CE1 1 
ATOM   512  N  NE2 . HIS A 1 62  ? 8.197   -29.129 54.011  1.00 68.05  ? 62  HIS B NE2 1 
ATOM   513  N  N   . ALA A 1 63  ? 14.163  -31.966 55.397  1.00 42.32  ? 63  ALA B N   1 
ATOM   514  C  CA  . ALA A 1 63  ? 15.221  -32.977 55.370  1.00 44.80  ? 63  ALA B CA  1 
ATOM   515  C  C   . ALA A 1 63  ? 15.613  -33.395 56.776  1.00 45.09  ? 63  ALA B C   1 
ATOM   516  O  O   . ALA A 1 63  ? 15.902  -34.570 57.030  1.00 39.42  ? 63  ALA B O   1 
ATOM   517  C  CB  . ALA A 1 63  ? 16.452  -32.461 54.617  1.00 37.90  ? 63  ALA B CB  1 
ATOM   518  N  N   . GLN A 1 64  ? 15.658  -32.439 57.697  1.00 44.03  ? 64  GLN B N   1 
ATOM   519  C  CA  . GLN A 1 64  ? 15.990  -32.773 59.066  1.00 44.65  ? 64  GLN B CA  1 
ATOM   520  C  C   . GLN A 1 64  ? 14.893  -33.608 59.712  1.00 50.58  ? 64  GLN B C   1 
ATOM   521  O  O   . GLN A 1 64  ? 15.189  -34.403 60.611  1.00 47.83  ? 64  GLN B O   1 
ATOM   522  C  CB  . GLN A 1 64  ? 16.271  -31.489 59.849  1.00 43.79  ? 64  GLN B CB  1 
ATOM   523  C  CG  . GLN A 1 64  ? 17.727  -31.057 59.749  1.00 45.96  ? 64  GLN B CG  1 
ATOM   524  C  CD  . GLN A 1 64  ? 17.988  -29.676 60.314  1.00 45.84  ? 64  GLN B CD  1 
ATOM   525  O  OE1 . GLN A 1 64  ? 18.653  -29.513 61.347  1.00 52.61  ? 64  GLN B OE1 1 
ATOM   526  N  NE2 . GLN A 1 64  ? 17.480  -28.671 59.633  1.00 49.73  ? 64  GLN B NE2 1 
ATOM   527  N  N   . THR A 1 65  ? 13.645  -33.484 59.237  1.00 47.19  ? 65  THR B N   1 
ATOM   528  C  CA  . THR A 1 65  ? 12.557  -34.288 59.786  1.00 38.98  ? 65  THR B CA  1 
ATOM   529  C  C   . THR A 1 65  ? 12.731  -35.754 59.422  1.00 42.74  ? 65  THR B C   1 
ATOM   530  O  O   . THR A 1 65  ? 12.561  -36.641 60.271  1.00 46.05  ? 65  THR B O   1 
ATOM   531  C  CB  . THR A 1 65  ? 11.218  -33.741 59.293  1.00 43.81  ? 65  THR B CB  1 
ATOM   532  O  OG1 . THR A 1 65  ? 10.940  -32.520 59.985  1.00 46.07  ? 65  THR B OG1 1 
ATOM   533  C  CG2 . THR A 1 65  ? 10.087  -34.717 59.536  1.00 37.68  ? 65  THR B CG2 1 
ATOM   534  N  N   . PHE A 1 66  ? 13.108  -36.026 58.175  1.00 39.84  ? 66  PHE B N   1 
ATOM   535  C  CA  . PHE A 1 66  ? 13.408  -37.391 57.776  1.00 39.13  ? 66  PHE B CA  1 
ATOM   536  C  C   . PHE A 1 66  ? 14.659  -37.922 58.463  1.00 46.62  ? 66  PHE B C   1 
ATOM   537  O  O   . PHE A 1 66  ? 14.720  -39.117 58.777  1.00 46.00  ? 66  PHE B O   1 
ATOM   538  C  CB  . PHE A 1 66  ? 13.566  -37.471 56.264  1.00 46.94  ? 66  PHE B CB  1 
ATOM   539  C  CG  . PHE A 1 66  ? 12.272  -37.407 55.528  1.00 51.94  ? 66  PHE B CG  1 
ATOM   540  C  CD1 . PHE A 1 66  ? 11.357  -38.448 55.626  1.00 57.68  ? 66  PHE B CD1 1 
ATOM   541  C  CD2 . PHE A 1 66  ? 11.957  -36.307 54.750  1.00 49.58  ? 66  PHE B CD2 1 
ATOM   542  C  CE1 . PHE A 1 66  ? 10.154  -38.393 54.958  1.00 60.90  ? 66  PHE B CE1 1 
ATOM   543  C  CE2 . PHE A 1 66  ? 10.753  -36.250 54.074  1.00 58.36  ? 66  PHE B CE2 1 
ATOM   544  C  CZ  . PHE A 1 66  ? 9.852   -37.293 54.177  1.00 60.03  ? 66  PHE B CZ  1 
ATOM   545  N  N   . MET A 1 67  ? 15.653  -37.057 58.715  1.00 41.24  ? 67  MET B N   1 
ATOM   546  C  CA  . MET A 1 67  ? 16.855  -37.500 59.414  1.00 38.95  ? 67  MET B CA  1 
ATOM   547  C  C   . MET A 1 67  ? 16.524  -37.952 60.838  1.00 42.99  ? 67  MET B C   1 
ATOM   548  O  O   . MET A 1 67  ? 16.984  -39.012 61.287  1.00 40.42  ? 67  MET B O   1 
ATOM   549  C  CB  . MET A 1 67  ? 17.917  -36.387 59.414  1.00 34.67  ? 67  MET B CB  1 
ATOM   550  C  CG  . MET A 1 67  ? 18.523  -36.043 58.041  1.00 35.53  ? 67  MET B CG  1 
ATOM   551  S  SD  . MET A 1 67  ? 19.707  -34.634 58.091  1.00 40.42  ? 67  MET B SD  1 
ATOM   552  C  CE  . MET A 1 67  ? 21.213  -35.438 58.647  1.00 37.71  ? 67  MET B CE  1 
ATOM   553  N  N   . LYS A 1 68  ? 15.727  -37.159 61.570  1.00 42.57  ? 68  LYS B N   1 
ATOM   554  C  CA  . LYS A 1 68  ? 15.270  -37.596 62.888  1.00 43.55  ? 68  LYS B CA  1 
ATOM   555  C  C   . LYS A 1 68  ? 14.491  -38.895 62.787  1.00 46.36  ? 68  LYS B C   1 
ATOM   556  O  O   . LYS A 1 68  ? 14.674  -39.808 63.601  1.00 46.24  ? 68  LYS B O   1 
ATOM   557  C  CB  . LYS A 1 68  ? 14.398  -36.534 63.556  1.00 43.86  ? 68  LYS B CB  1 
ATOM   558  C  CG  . LYS A 1 68  ? 15.144  -35.411 64.210  1.00 60.17  ? 68  LYS B CG  1 
ATOM   559  C  CD  . LYS A 1 68  ? 14.180  -34.322 64.636  1.00 65.22  ? 68  LYS B CD  1 
ATOM   560  C  CE  . LYS A 1 68  ? 14.153  -33.187 63.611  1.00 66.31  ? 68  LYS B CE  1 
ATOM   561  N  NZ  . LYS A 1 68  ? 14.410  -31.849 64.234  1.00 70.26  ? 68  LYS B NZ  1 
ATOM   562  N  N   . TYR A 1 69  ? 13.603  -38.995 61.797  1.00 42.71  ? 69  TYR B N   1 
ATOM   563  C  CA  . TYR A 1 69  ? 12.793  -40.198 61.715  1.00 48.98  ? 69  TYR B CA  1 
ATOM   564  C  C   . TYR A 1 69  ? 13.663  -41.413 61.459  1.00 48.86  ? 69  TYR B C   1 
ATOM   565  O  O   . TYR A 1 69  ? 13.434  -42.482 62.040  1.00 47.42  ? 69  TYR B O   1 
ATOM   566  C  CB  . TYR A 1 69  ? 11.734  -40.072 60.632  1.00 47.10  ? 69  TYR B CB  1 
ATOM   567  C  CG  . TYR A 1 69  ? 10.825  -41.261 60.644  1.00 47.36  ? 69  TYR B CG  1 
ATOM   568  C  CD1 . TYR A 1 69  ? 9.792   -41.344 61.569  1.00 57.35  ? 69  TYR B CD1 1 
ATOM   569  C  CD2 . TYR A 1 69  ? 11.011  -42.317 59.763  1.00 49.61  ? 69  TYR B CD2 1 
ATOM   570  C  CE1 . TYR A 1 69  ? 8.956   -42.434 61.603  1.00 59.94  ? 69  TYR B CE1 1 
ATOM   571  C  CE2 . TYR A 1 69  ? 10.181  -43.419 59.792  1.00 54.86  ? 69  TYR B CE2 1 
ATOM   572  C  CZ  . TYR A 1 69  ? 9.153   -43.464 60.715  1.00 58.56  ? 69  TYR B CZ  1 
ATOM   573  O  OH  . TYR A 1 69  ? 8.314   -44.542 60.766  1.00 61.91  ? 69  TYR B OH  1 
ATOM   574  N  N   . GLN A 1 70  ? 14.659  -41.267 60.584  1.00 44.01  ? 70  GLN B N   1 
ATOM   575  C  CA  . GLN A 1 70  ? 15.604  -42.343 60.334  1.00 44.06  ? 70  GLN B CA  1 
ATOM   576  C  C   . GLN A 1 70  ? 16.217  -42.819 61.642  1.00 50.72  ? 70  GLN B C   1 
ATOM   577  O  O   . GLN A 1 70  ? 16.125  -43.999 62.000  1.00 48.50  ? 70  GLN B O   1 
ATOM   578  C  CB  . GLN A 1 70  ? 16.691  -41.860 59.380  1.00 48.70  ? 70  GLN B CB  1 
ATOM   579  C  CG  . GLN A 1 70  ? 17.721  -42.910 59.028  1.00 47.92  ? 70  GLN B CG  1 
ATOM   580  C  CD  . GLN A 1 70  ? 17.214  -43.828 57.947  1.00 51.24  ? 70  GLN B CD  1 
ATOM   581  O  OE1 . GLN A 1 70  ? 16.330  -44.644 58.181  1.00 46.82  ? 70  GLN B OE1 1 
ATOM   582  N  NE2 . GLN A 1 70  ? 17.763  -43.692 56.751  1.00 49.51  ? 70  GLN B NE2 1 
ATOM   583  N  N   . ASN A 1 71  ? 16.832  -41.884 62.374  1.00 48.45  ? 71  ASN B N   1 
ATOM   584  C  CA  . ASN A 1 71  ? 17.430  -42.181 63.672  1.00 49.20  ? 71  ASN B CA  1 
ATOM   585  C  C   . ASN A 1 71  ? 16.431  -42.822 64.617  1.00 54.86  ? 71  ASN B C   1 
ATOM   586  O  O   . ASN A 1 71  ? 16.752  -43.787 65.327  1.00 58.11  ? 71  ASN B O   1 
ATOM   587  C  CB  . ASN A 1 71  ? 17.972  -40.896 64.299  1.00 37.00  ? 71  ASN B CB  1 
ATOM   588  C  CG  . ASN A 1 71  ? 19.405  -40.654 63.938  1.00 37.67  ? 71  ASN B CG  1 
ATOM   589  O  OD1 . ASN A 1 71  ? 20.074  -41.539 63.385  1.00 40.24  ? 71  ASN B OD1 1 
ATOM   590  N  ND2 . ASN A 1 71  ? 19.897  -39.455 64.235  1.00 38.09  ? 71  ASN B ND2 1 
ATOM   591  N  N   . CYS A 1 72  ? 15.216  -42.280 64.638  1.00 53.22  ? 72  CYS B N   1 
ATOM   592  C  CA  . CYS A 1 72  ? 14.198  -42.705 65.586  1.00 58.77  ? 72  CYS B CA  1 
ATOM   593  C  C   . CYS A 1 72  ? 13.817  -44.173 65.383  1.00 56.42  ? 72  CYS B C   1 
ATOM   594  O  O   . CYS A 1 72  ? 13.655  -44.921 66.353  1.00 63.12  ? 72  CYS B O   1 
ATOM   595  C  CB  . CYS A 1 72  ? 12.993  -41.786 65.435  1.00 61.45  ? 72  CYS B CB  1 
ATOM   596  S  SG  . CYS A 1 72  ? 11.768  -41.968 66.689  1.00 90.38  ? 72  CYS B SG  1 
ATOM   597  N  N   . ARG A 1 73  ? 13.693  -44.609 64.138  1.00 47.96  ? 73  ARG B N   1 
ATOM   598  C  CA  . ARG A 1 73  ? 13.426  -46.002 63.835  1.00 47.64  ? 73  ARG B CA  1 
ATOM   599  C  C   . ARG A 1 73  ? 14.690  -46.857 63.790  1.00 55.13  ? 73  ARG B C   1 
ATOM   600  O  O   . ARG A 1 73  ? 14.619  -48.025 63.405  1.00 58.34  ? 73  ARG B O   1 
ATOM   601  C  CB  . ARG A 1 73  ? 12.680  -46.106 62.506  1.00 51.98  ? 73  ARG B CB  1 
ATOM   602  C  CG  . ARG A 1 73  ? 11.369  -45.334 62.505  1.00 60.67  ? 73  ARG B CG  1 
ATOM   603  C  CD  . ARG A 1 73  ? 10.319  -45.973 63.415  1.00 60.54  ? 73  ARG B CD  1 
ATOM   604  N  NE  . ARG A 1 73  ? 10.066  -47.358 63.033  1.00 68.68  ? 73  ARG B NE  1 
ATOM   605  C  CZ  . ARG A 1 73  ? 9.333   -47.732 61.989  1.00 63.69  ? 73  ARG B CZ  1 
ATOM   606  N  NH1 . ARG A 1 73  ? 8.756   -46.828 61.215  1.00 60.12  ? 73  ARG B NH1 1 
ATOM   607  N  NH2 . ARG A 1 73  ? 9.180   -49.018 61.721  1.00 67.76  ? 73  ARG B NH2 1 
ATOM   608  N  N   . GLY A 1 74  ? 15.844  -46.305 64.152  1.00 56.71  ? 74  GLY B N   1 
ATOM   609  C  CA  . GLY A 1 74  ? 17.062  -47.084 64.167  1.00 51.75  ? 74  GLY B CA  1 
ATOM   610  C  C   . GLY A 1 74  ? 17.707  -47.344 62.823  1.00 51.47  ? 74  GLY B C   1 
ATOM   611  O  O   . GLY A 1 74  ? 18.598  -48.194 62.743  1.00 58.68  ? 74  GLY B O   1 
ATOM   612  N  N   . GLY A 1 75  ? 17.304  -46.650 61.766  1.00 49.67  ? 75  GLY B N   1 
ATOM   613  C  CA  . GLY A 1 75  ? 18.068  -46.694 60.535  1.00 50.84  ? 75  GLY B CA  1 
ATOM   614  C  C   . GLY A 1 75  ? 19.345  -45.868 60.617  1.00 44.90  ? 75  GLY B C   1 
ATOM   615  O  O   . GLY A 1 75  ? 19.584  -45.106 61.561  1.00 37.08  ? 75  GLY B O   1 
ATOM   616  N  N   . ARG A 1 76  ? 20.180  -46.028 59.590  1.00 43.49  ? 76  ARG B N   1 
ATOM   617  C  CA  . ARG A 1 76  ? 21.432  -45.287 59.452  1.00 43.51  ? 76  ARG B CA  1 
ATOM   618  C  C   . ARG A 1 76  ? 21.269  -44.163 58.418  1.00 46.25  ? 76  ARG B C   1 
ATOM   619  O  O   . ARG A 1 76  ? 20.992  -44.420 57.239  1.00 42.59  ? 76  ARG B O   1 
ATOM   620  C  CB  . ARG A 1 76  ? 22.577  -46.228 59.055  1.00 48.59  ? 76  ARG B CB  1 
ATOM   621  C  CG  . ARG A 1 76  ? 23.863  -45.502 58.550  1.00 66.17  ? 76  ARG B CG  1 
ATOM   622  C  CD  . ARG A 1 76  ? 25.122  -46.396 58.539  1.00 67.12  ? 76  ARG B CD  1 
ATOM   623  N  NE  . ARG A 1 76  ? 25.624  -46.626 59.897  1.00 82.47  ? 76  ARG B NE  1 
ATOM   624  C  CZ  . ARG A 1 76  ? 25.640  -47.809 60.514  1.00 85.22  ? 76  ARG B CZ  1 
ATOM   625  N  NH1 . ARG A 1 76  ? 25.188  -48.906 59.900  1.00 77.14  ? 76  ARG B NH1 1 
ATOM   626  N  NH2 . ARG A 1 76  ? 26.116  -47.892 61.753  1.00 80.05  ? 76  ARG B NH2 1 
ATOM   627  N  N   . ILE A 1 77  ? 21.439  -42.916 58.862  1.00 46.49  ? 77  ILE B N   1 
ATOM   628  C  CA  . ILE A 1 77  ? 21.503  -41.808 57.920  1.00 44.53  ? 77  ILE B CA  1 
ATOM   629  C  C   . ILE A 1 77  ? 22.738  -41.977 57.054  1.00 40.91  ? 77  ILE B C   1 
ATOM   630  O  O   . ILE A 1 77  ? 23.844  -42.194 57.564  1.00 42.92  ? 77  ILE B O   1 
ATOM   631  C  CB  . ILE A 1 77  ? 21.526  -40.466 58.670  1.00 35.17  ? 77  ILE B CB  1 
ATOM   632  C  CG1 . ILE A 1 77  ? 20.209  -40.235 59.407  1.00 35.96  ? 77  ILE B CG1 1 
ATOM   633  C  CG2 . ILE A 1 77  ? 21.793  -39.325 57.697  1.00 38.08  ? 77  ILE B CG2 1 
ATOM   634  C  CD1 . ILE A 1 77  ? 20.355  -39.380 60.634  1.00 41.17  ? 77  ILE B CD1 1 
ATOM   635  N  N   . VAL A 1 78  ? 22.559  -41.891 55.738  1.00 40.00  ? 78  VAL B N   1 
ATOM   636  C  CA  . VAL A 1 78  ? 23.668  -41.914 54.786  1.00 42.62  ? 78  VAL B CA  1 
ATOM   637  C  C   . VAL A 1 78  ? 23.551  -40.682 53.897  1.00 42.84  ? 78  VAL B C   1 
ATOM   638  O  O   . VAL A 1 78  ? 22.592  -40.555 53.123  1.00 41.22  ? 78  VAL B O   1 
ATOM   639  C  CB  . VAL A 1 78  ? 23.698  -43.196 53.945  1.00 45.34  ? 78  VAL B CB  1 
ATOM   640  C  CG1 . VAL A 1 78  ? 24.887  -43.168 52.999  1.00 29.28  ? 78  VAL B CG1 1 
ATOM   641  C  CG2 . VAL A 1 78  ? 23.787  -44.419 54.858  1.00 43.73  ? 78  VAL B CG2 1 
ATOM   642  N  N   . LEU A 1 79  ? 24.516  -39.775 54.010  1.00 38.85  ? 79  LEU B N   1 
ATOM   643  C  CA  . LEU A 1 79  ? 24.444  -38.481 53.353  1.00 38.03  ? 79  LEU B CA  1 
ATOM   644  C  C   . LEU A 1 79  ? 25.315  -38.491 52.105  1.00 37.71  ? 79  LEU B C   1 
ATOM   645  O  O   . LEU A 1 79  ? 26.494  -38.847 52.154  1.00 42.55  ? 79  LEU B O   1 
ATOM   646  C  CB  . LEU A 1 79  ? 24.857  -37.358 54.308  1.00 29.97  ? 79  LEU B CB  1 
ATOM   647  C  CG  . LEU A 1 79  ? 23.897  -37.139 55.476  1.00 35.21  ? 79  LEU B CG  1 
ATOM   648  C  CD1 . LEU A 1 79  ? 24.448  -36.090 56.438  1.00 35.34  ? 79  LEU B CD1 1 
ATOM   649  C  CD2 . LEU A 1 79  ? 22.507  -36.711 54.975  1.00 22.46  ? 79  LEU B CD2 1 
ATOM   650  N  N   . GLN A 1 80  ? 24.722  -38.113 50.991  1.00 39.52  ? 80  GLN B N   1 
ATOM   651  C  CA  . GLN A 1 80  ? 25.381  -38.131 49.705  1.00 40.16  ? 80  GLN B CA  1 
ATOM   652  C  C   . GLN A 1 80  ? 25.555  -36.704 49.192  1.00 39.22  ? 80  GLN B C   1 
ATOM   653  O  O   . GLN A 1 80  ? 24.988  -35.745 49.741  1.00 35.51  ? 80  GLN B O   1 
ATOM   654  C  CB  . GLN A 1 80  ? 24.574  -39.005 48.742  1.00 38.94  ? 80  GLN B CB  1 
ATOM   655  C  CG  . GLN A 1 80  ? 25.012  -40.473 48.794  1.00 47.64  ? 80  GLN B CG  1 
ATOM   656  C  CD  . GLN A 1 80  ? 23.877  -41.432 48.537  1.00 60.75  ? 80  GLN B CD  1 
ATOM   657  O  OE1 . GLN A 1 80  ? 23.659  -41.869 47.402  1.00 61.11  ? 80  GLN B OE1 1 
ATOM   658  N  NE2 . GLN A 1 80  ? 23.133  -41.767 49.594  1.00 70.31  ? 80  GLN B NE2 1 
ATOM   659  N  N   . GLN A 1 81  ? 26.364  -36.565 48.133  1.00 38.82  ? 81  GLN B N   1 
ATOM   660  C  CA  . GLN A 1 81  ? 26.629  -35.246 47.570  1.00 35.32  ? 81  GLN B CA  1 
ATOM   661  C  C   . GLN A 1 81  ? 25.319  -34.552 47.197  1.00 37.27  ? 81  GLN B C   1 
ATOM   662  O  O   . GLN A 1 81  ? 24.320  -35.190 46.857  1.00 37.62  ? 81  GLN B O   1 
ATOM   663  C  CB  . GLN A 1 81  ? 27.529  -35.347 46.345  1.00 31.21  ? 81  GLN B CB  1 
ATOM   664  C  CG  . GLN A 1 81  ? 26.948  -36.228 45.231  1.00 37.96  ? 81  GLN B CG  1 
ATOM   665  C  CD  . GLN A 1 81  ? 28.050  -36.886 44.411  1.00 44.32  ? 81  GLN B CD  1 
ATOM   666  O  OE1 . GLN A 1 81  ? 29.129  -37.191 44.937  1.00 35.23  ? 81  GLN B OE1 1 
ATOM   667  N  NE2 . GLN A 1 81  ? 27.789  -37.106 43.118  1.00 43.39  ? 81  GLN B NE2 1 
ATOM   668  N  N   . ILE A 1 82  ? 25.316  -33.234 47.301  1.00 31.30  ? 82  ILE B N   1 
ATOM   669  C  CA  . ILE A 1 82  ? 24.163  -32.430 46.932  1.00 34.11  ? 82  ILE B CA  1 
ATOM   670  C  C   . ILE A 1 82  ? 24.529  -31.715 45.638  1.00 33.73  ? 82  ILE B C   1 
ATOM   671  O  O   . ILE A 1 82  ? 25.330  -30.775 45.647  1.00 32.98  ? 82  ILE B O   1 
ATOM   672  C  CB  . ILE A 1 82  ? 23.783  -31.434 48.037  1.00 33.61  ? 82  ILE B CB  1 
ATOM   673  C  CG1 . ILE A 1 82  ? 23.814  -32.106 49.407  1.00 33.28  ? 82  ILE B CG1 1 
ATOM   674  C  CG2 . ILE A 1 82  ? 22.404  -30.833 47.769  1.00 33.41  ? 82  ILE B CG2 1 
ATOM   675  C  CD1 . ILE A 1 82  ? 23.692  -31.150 50.555  1.00 28.37  ? 82  ILE B CD1 1 
ATOM   676  N  N   . ALA A 1 83  ? 23.967  -32.171 44.522  1.00 34.42  ? 83  ALA B N   1 
ATOM   677  C  CA  . ALA A 1 83  ? 24.265  -31.555 43.237  1.00 34.65  ? 83  ALA B CA  1 
ATOM   678  C  C   . ALA A 1 83  ? 23.835  -30.093 43.235  1.00 38.04  ? 83  ALA B C   1 
ATOM   679  O  O   . ALA A 1 83  ? 22.835  -29.717 43.858  1.00 40.17  ? 83  ALA B O   1 
ATOM   680  C  CB  . ALA A 1 83  ? 23.560  -32.318 42.105  1.00 26.74  ? 83  ALA B CB  1 
ATOM   681  N  N   . ALA A 1 84  ? 24.603  -29.255 42.548  1.00 32.37  ? 84  ALA B N   1 
ATOM   682  C  CA  . ALA A 1 84  ? 24.139  -27.895 42.326  1.00 36.60  ? 84  ALA B CA  1 
ATOM   683  C  C   . ALA A 1 84  ? 23.049  -27.902 41.254  1.00 38.59  ? 84  ALA B C   1 
ATOM   684  O  O   . ALA A 1 84  ? 23.017  -28.799 40.400  1.00 35.68  ? 84  ALA B O   1 
ATOM   685  C  CB  . ALA A 1 84  ? 25.296  -26.990 41.891  1.00 33.26  ? 84  ALA B CB  1 
ATOM   686  N  N   . PRO A 1 85  ? 22.155  -26.907 41.259  1.00 40.98  ? 85  PRO B N   1 
ATOM   687  C  CA  . PRO A 1 85  ? 21.196  -26.780 40.153  1.00 34.34  ? 85  PRO B CA  1 
ATOM   688  C  C   . PRO A 1 85  ? 21.942  -26.709 38.831  1.00 33.59  ? 85  PRO B C   1 
ATOM   689  O  O   . PRO A 1 85  ? 22.993  -26.077 38.731  1.00 39.72  ? 85  PRO B O   1 
ATOM   690  C  CB  . PRO A 1 85  ? 20.465  -25.472 40.458  1.00 34.55  ? 85  PRO B CB  1 
ATOM   691  C  CG  . PRO A 1 85  ? 20.721  -25.232 41.952  1.00 37.84  ? 85  PRO B CG  1 
ATOM   692  C  CD  . PRO A 1 85  ? 22.090  -25.761 42.186  1.00 32.61  ? 85  PRO B CD  1 
ATOM   693  N  N   . SER A 1 86  ? 21.402  -27.377 37.811  1.00 31.05  ? 86  SER B N   1 
ATOM   694  C  CA  . SER A 1 86  ? 22.062  -27.381 36.505  1.00 34.27  ? 86  SER B CA  1 
ATOM   695  C  C   . SER A 1 86  ? 21.958  -26.032 35.818  1.00 40.30  ? 86  SER B C   1 
ATOM   696  O  O   . SER A 1 86  ? 22.841  -25.664 35.029  1.00 37.16  ? 86  SER B O   1 
ATOM   697  C  CB  . SER A 1 86  ? 21.458  -28.449 35.600  1.00 35.20  ? 86  SER B CB  1 
ATOM   698  O  OG  . SER A 1 86  ? 20.065  -28.270 35.508  1.00 49.46  ? 86  SER B OG  1 
ATOM   699  N  N   . MET A 1 87  ? 20.897  -25.283 36.105  1.00 36.74  ? 87  MET B N   1 
ATOM   700  C  CA  . MET A 1 87  ? 20.592  -24.049 35.395  1.00 41.81  ? 87  MET B CA  1 
ATOM   701  C  C   . MET A 1 87  ? 20.327  -22.975 36.443  1.00 43.39  ? 87  MET B C   1 
ATOM   702  O  O   . MET A 1 87  ? 19.262  -22.967 37.073  1.00 45.51  ? 87  MET B O   1 
ATOM   703  C  CB  . MET A 1 87  ? 19.396  -24.242 34.456  1.00 41.94  ? 87  MET B CB  1 
ATOM   704  C  CG  . MET A 1 87  ? 19.502  -23.468 33.171  1.00 50.05  ? 87  MET B CG  1 
ATOM   705  S  SD  . MET A 1 87  ? 19.104  -21.750 33.525  1.00 65.04  ? 87  MET B SD  1 
ATOM   706  C  CE  . MET A 1 87  ? 17.506  -21.983 34.359  1.00 47.22  ? 87  MET B CE  1 
ATOM   707  N  N   . ARG A 1 88  ? 21.292  -22.070 36.617  1.00 41.09  ? 88  ARG B N   1 
ATOM   708  C  CA  . ARG A 1 88  ? 21.288  -21.108 37.708  1.00 42.55  ? 88  ARG B CA  1 
ATOM   709  C  C   . ARG A 1 88  ? 20.996  -19.679 37.262  1.00 45.19  ? 88  ARG B C   1 
ATOM   710  O  O   . ARG A 1 88  ? 20.984  -18.771 38.106  1.00 41.32  ? 88  ARG B O   1 
ATOM   711  C  CB  . ARG A 1 88  ? 22.632  -21.193 38.446  1.00 36.84  ? 88  ARG B CB  1 
ATOM   712  C  CG  . ARG A 1 88  ? 22.783  -22.569 39.096  1.00 42.87  ? 88  ARG B CG  1 
ATOM   713  C  CD  . ARG A 1 88  ? 24.113  -22.879 39.748  1.00 31.36  ? 88  ARG B CD  1 
ATOM   714  N  NE  . ARG A 1 88  ? 24.811  -21.715 40.241  1.00 30.04  ? 88  ARG B NE  1 
ATOM   715  C  CZ  . ARG A 1 88  ? 24.324  -20.814 41.104  1.00 49.99  ? 88  ARG B CZ  1 
ATOM   716  N  NH1 . ARG A 1 88  ? 23.081  -20.870 41.590  1.00 49.90  ? 88  ARG B NH1 1 
ATOM   717  N  NH2 . ARG A 1 88  ? 25.087  -19.803 41.483  1.00 58.46  ? 88  ARG B NH2 1 
ATOM   718  N  N   . GLU A 1 89  ? 20.784  -19.456 35.961  1.00 44.95  ? 89  GLU B N   1 
ATOM   719  C  CA  . GLU A 1 89  ? 20.207  -18.219 35.431  1.00 48.35  ? 89  GLU B CA  1 
ATOM   720  C  C   . GLU A 1 89  ? 18.691  -18.392 35.393  1.00 46.16  ? 89  GLU B C   1 
ATOM   721  O  O   . GLU A 1 89  ? 18.112  -18.797 34.383  1.00 46.19  ? 89  GLU B O   1 
ATOM   722  C  CB  . GLU A 1 89  ? 20.753  -17.916 34.040  1.00 52.04  ? 89  GLU B CB  1 
ATOM   723  C  CG  . GLU A 1 89  ? 22.184  -17.455 34.019  1.00 54.18  ? 89  GLU B CG  1 
ATOM   724  C  CD  . GLU A 1 89  ? 22.312  -16.046 34.527  1.00 63.81  ? 89  GLU B CD  1 
ATOM   725  O  OE1 . GLU A 1 89  ? 23.416  -15.704 35.001  1.00 71.71  ? 89  GLU B OE1 1 
ATOM   726  O  OE2 . GLU A 1 89  ? 21.310  -15.283 34.452  1.00 63.39  ? 89  GLU B OE2 1 
ATOM   727  N  N   . TRP A 1 90  ? 18.033  -18.056 36.496  1.00 39.73  ? 90  TRP B N   1 
ATOM   728  C  CA  . TRP A 1 90  ? 16.620  -18.375 36.616  1.00 42.57  ? 90  TRP B CA  1 
ATOM   729  C  C   . TRP A 1 90  ? 15.734  -17.493 35.749  1.00 37.64  ? 90  TRP B C   1 
ATOM   730  O  O   . TRP A 1 90  ? 14.586  -17.864 35.503  1.00 42.31  ? 90  TRP B O   1 
ATOM   731  C  CB  . TRP A 1 90  ? 16.209  -18.298 38.079  1.00 35.38  ? 90  TRP B CB  1 
ATOM   732  C  CG  . TRP A 1 90  ? 16.995  -19.226 38.860  1.00 37.71  ? 90  TRP B CG  1 
ATOM   733  C  CD1 . TRP A 1 90  ? 18.038  -18.932 39.694  1.00 34.43  ? 90  TRP B CD1 1 
ATOM   734  C  CD2 . TRP A 1 90  ? 16.855  -20.647 38.863  1.00 36.62  ? 90  TRP B CD2 1 
ATOM   735  N  NE1 . TRP A 1 90  ? 18.544  -20.090 40.228  1.00 34.92  ? 90  TRP B NE1 1 
ATOM   736  C  CE2 . TRP A 1 90  ? 17.830  -21.158 39.740  1.00 36.46  ? 90  TRP B CE2 1 
ATOM   737  C  CE3 . TRP A 1 90  ? 15.995  -21.535 38.217  1.00 36.18  ? 90  TRP B CE3 1 
ATOM   738  C  CZ2 . TRP A 1 90  ? 17.965  -22.529 39.989  1.00 37.71  ? 90  TRP B CZ2 1 
ATOM   739  C  CZ3 . TRP A 1 90  ? 16.131  -22.900 38.462  1.00 35.65  ? 90  TRP B CZ3 1 
ATOM   740  C  CH2 . TRP A 1 90  ? 17.109  -23.380 39.340  1.00 37.87  ? 90  TRP B CH2 1 
ATOM   741  N  N   . GLY A 1 91  ? 16.231  -16.359 35.271  1.00 40.51  ? 91  GLY B N   1 
ATOM   742  C  CA  . GLY A 1 91  ? 15.489  -15.572 34.300  1.00 37.17  ? 91  GLY B CA  1 
ATOM   743  C  C   . GLY A 1 91  ? 14.488  -14.657 34.972  1.00 44.25  ? 91  GLY B C   1 
ATOM   744  O  O   . GLY A 1 91  ? 14.809  -14.022 35.983  1.00 41.98  ? 91  GLY B O   1 
ATOM   745  N  N   . THR A 1 92  ? 13.267  -14.588 34.438  1.00 46.88  ? 92  THR B N   1 
ATOM   746  C  CA  . THR A 1 92  ? 12.231  -13.780 35.066  1.00 45.47  ? 92  THR B CA  1 
ATOM   747  C  C   . THR A 1 92  ? 11.695  -14.457 36.314  1.00 44.05  ? 92  THR B C   1 
ATOM   748  O  O   . THR A 1 92  ? 11.893  -15.655 36.549  1.00 42.74  ? 92  THR B O   1 
ATOM   749  C  CB  . THR A 1 92  ? 11.064  -13.561 34.131  1.00 43.65  ? 92  THR B CB  1 
ATOM   750  O  OG1 . THR A 1 92  ? 10.440  -14.830 33.895  1.00 43.44  ? 92  THR B OG1 1 
ATOM   751  C  CG2 . THR A 1 92  ? 11.566  -12.971 32.820  1.00 50.96  ? 92  THR B CG2 1 
ATOM   752  N  N   . GLY A 1 93  ? 10.978  -13.662 37.106  1.00 40.14  ? 93  GLY B N   1 
ATOM   753  C  CA  . GLY A 1 93  ? 10.335  -14.202 38.286  1.00 42.28  ? 93  GLY B CA  1 
ATOM   754  C  C   . GLY A 1 93  ? 9.345   -15.294 37.946  1.00 41.49  ? 93  GLY B C   1 
ATOM   755  O  O   . GLY A 1 93  ? 9.230   -16.287 38.671  1.00 44.19  ? 93  GLY B O   1 
ATOM   756  N  N   . LEU A 1 94  ? 8.621   -15.134 36.835  1.00 39.18  ? 94  LEU B N   1 
ATOM   757  C  CA  . LEU A 1 94  ? 7.680   -16.176 36.436  1.00 40.83  ? 94  LEU B CA  1 
ATOM   758  C  C   . LEU A 1 94  ? 8.408   -17.475 36.150  1.00 41.74  ? 94  LEU B C   1 
ATOM   759  O  O   . LEU A 1 94  ? 7.987   -18.541 36.613  1.00 45.49  ? 94  LEU B O   1 
ATOM   760  C  CB  . LEU A 1 94  ? 6.864   -15.748 35.215  1.00 35.63  ? 94  LEU B CB  1 
ATOM   761  C  CG  . LEU A 1 94  ? 5.936   -16.826 34.660  1.00 38.72  ? 94  LEU B CG  1 
ATOM   762  C  CD1 . LEU A 1 94  ? 4.896   -17.214 35.732  1.00 39.09  ? 94  LEU B CD1 1 
ATOM   763  C  CD2 . LEU A 1 94  ? 5.254   -16.354 33.385  1.00 31.29  ? 94  LEU B CD2 1 
ATOM   764  N  N   . GLU A 1 95  ? 9.508   -17.409 35.397  1.00 39.28  ? 95  GLU B N   1 
ATOM   765  C  CA  . GLU A 1 95  ? 10.235  -18.631 35.071  1.00 44.84  ? 95  GLU B CA  1 
ATOM   766  C  C   . GLU A 1 95  ? 10.750  -19.317 36.332  1.00 42.69  ? 95  GLU B C   1 
ATOM   767  O  O   . GLU A 1 95  ? 10.724  -20.549 36.431  1.00 39.69  ? 95  GLU B O   1 
ATOM   768  C  CB  . GLU A 1 95  ? 11.387  -18.320 34.125  1.00 45.07  ? 95  GLU B CB  1 
ATOM   769  C  CG  . GLU A 1 95  ? 10.958  -17.829 32.757  1.00 49.76  ? 95  GLU B CG  1 
ATOM   770  C  CD  . GLU A 1 95  ? 12.142  -17.320 31.944  1.00 54.24  ? 95  GLU B CD  1 
ATOM   771  O  OE1 . GLU A 1 95  ? 12.915  -16.477 32.468  1.00 51.10  ? 95  GLU B OE1 1 
ATOM   772  O  OE2 . GLU A 1 95  ? 12.302  -17.772 30.790  1.00 58.15  ? 95  GLU B OE2 1 
ATOM   773  N  N   . ALA A 1 96  ? 11.217  -18.536 37.308  1.00 34.30  ? 96  ALA B N   1 
ATOM   774  C  CA  . ALA A 1 96  ? 11.665  -19.132 38.557  1.00 39.05  ? 96  ALA B CA  1 
ATOM   775  C  C   . ALA A 1 96  ? 10.512  -19.851 39.253  1.00 40.86  ? 96  ALA B C   1 
ATOM   776  O  O   . ALA A 1 96  ? 10.667  -20.981 39.740  1.00 39.25  ? 96  ALA B O   1 
ATOM   777  C  CB  . ALA A 1 96  ? 12.277  -18.057 39.460  1.00 33.70  ? 96  ALA B CB  1 
ATOM   778  N  N   . LEU A 1 97  ? 9.340   -19.220 39.280  1.00 39.47  ? 97  LEU B N   1 
ATOM   779  C  CA  . LEU A 1 97  ? 8.173   -19.833 39.900  1.00 41.94  ? 97  LEU B CA  1 
ATOM   780  C  C   . LEU A 1 97  ? 7.775   -21.110 39.179  1.00 40.47  ? 97  LEU B C   1 
ATOM   781  O  O   . LEU A 1 97  ? 7.370   -22.088 39.820  1.00 40.12  ? 97  LEU B O   1 
ATOM   782  C  CB  . LEU A 1 97  ? 7.005   -18.846 39.904  1.00 42.12  ? 97  LEU B CB  1 
ATOM   783  C  CG  . LEU A 1 97  ? 7.164   -17.672 40.849  1.00 37.25  ? 97  LEU B CG  1 
ATOM   784  C  CD1 . LEU A 1 97  ? 6.057   -16.677 40.573  1.00 37.51  ? 97  LEU B CD1 1 
ATOM   785  C  CD2 . LEU A 1 97  ? 7.126   -18.187 42.262  1.00 34.24  ? 97  LEU B CD2 1 
ATOM   786  N  N   . GLN A 1 98  ? 7.867   -21.116 37.845  1.00 41.46  ? 98  GLN B N   1 
ATOM   787  C  CA  . GLN A 1 98  ? 7.538   -22.326 37.096  1.00 41.72  ? 98  GLN B CA  1 
ATOM   788  C  C   . GLN A 1 98  ? 8.554   -23.424 37.361  1.00 38.60  ? 98  GLN B C   1 
ATOM   789  O  O   . GLN A 1 98  ? 8.182   -24.594 37.488  1.00 43.71  ? 98  GLN B O   1 
ATOM   790  C  CB  . GLN A 1 98  ? 7.426   -22.007 35.605  1.00 37.63  ? 98  GLN B CB  1 
ATOM   791  C  CG  . GLN A 1 98  ? 6.321   -20.968 35.328  1.00 50.16  ? 98  GLN B CG  1 
ATOM   792  C  CD  . GLN A 1 98  ? 6.313   -20.397 33.900  1.00 58.35  ? 98  GLN B CD  1 
ATOM   793  O  OE1 . GLN A 1 98  ? 7.358   -20.039 33.341  1.00 56.37  ? 98  GLN B OE1 1 
ATOM   794  N  NE2 . GLN A 1 98  ? 5.118   -20.298 33.316  1.00 55.08  ? 98  GLN B NE2 1 
ATOM   795  N  N   . ALA A 1 99  ? 9.839   -23.062 37.486  1.00 36.95  ? 99  ALA B N   1 
ATOM   796  C  CA  . ALA A 1 99  ? 10.854  -24.030 37.893  1.00 39.01  ? 99  ALA B CA  1 
ATOM   797  C  C   . ALA A 1 99  ? 10.593  -24.573 39.296  1.00 39.00  ? 99  ALA B C   1 
ATOM   798  O  O   . ALA A 1 99  ? 10.825  -25.762 39.556  1.00 39.23  ? 99  ALA B O   1 
ATOM   799  C  CB  . ALA A 1 99  ? 12.244  -23.398 37.823  1.00 34.98  ? 99  ALA B CB  1 
ATOM   800  N  N   . ALA A 1 100 ? 10.105  -23.730 40.207  1.00 35.33  ? 100 ALA B N   1 
ATOM   801  C  CA  . ALA A 1 100 ? 9.852   -24.177 41.581  1.00 46.15  ? 100 ALA B CA  1 
ATOM   802  C  C   . ALA A 1 100 ? 8.621   -25.079 41.673  1.00 45.22  ? 100 ALA B C   1 
ATOM   803  O  O   . ALA A 1 100 ? 8.603   -26.027 42.470  1.00 47.47  ? 100 ALA B O   1 
ATOM   804  C  CB  . ALA A 1 100 ? 9.703   -22.975 42.524  1.00 35.80  ? 100 ALA B CB  1 
ATOM   805  N  N   . LEU A 1 101 ? 7.587   -24.797 40.877  1.00 40.26  ? 101 LEU B N   1 
ATOM   806  C  CA  . LEU A 1 101 ? 6.435   -25.688 40.829  1.00 39.84  ? 101 LEU B CA  1 
ATOM   807  C  C   . LEU A 1 101 ? 6.834   -27.072 40.349  1.00 49.29  ? 101 LEU B C   1 
ATOM   808  O  O   . LEU A 1 101 ? 6.375   -28.082 40.904  1.00 47.62  ? 101 LEU B O   1 
ATOM   809  C  CB  . LEU A 1 101 ? 5.342   -25.121 39.926  1.00 39.10  ? 101 LEU B CB  1 
ATOM   810  C  CG  . LEU A 1 101 ? 4.097   -26.023 39.923  1.00 44.62  ? 101 LEU B CG  1 
ATOM   811  C  CD1 . LEU A 1 101 ? 3.378   -25.970 41.295  1.00 43.37  ? 101 LEU B CD1 1 
ATOM   812  C  CD2 . LEU A 1 101 ? 3.153   -25.707 38.768  1.00 37.14  ? 101 LEU B CD2 1 
ATOM   813  N  N   . ASP A 1 102 ? 7.683   -27.142 39.313  1.00 47.08  ? 102 ASP B N   1 
ATOM   814  C  CA  . ASP A 1 102 ? 8.219   -28.429 38.875  1.00 41.88  ? 102 ASP B CA  1 
ATOM   815  C  C   . ASP A 1 102 ? 9.005   -29.098 39.989  1.00 45.23  ? 102 ASP B C   1 
ATOM   816  O  O   . ASP A 1 102 ? 8.834   -30.295 40.250  1.00 48.19  ? 102 ASP B O   1 
ATOM   817  C  CB  . ASP A 1 102 ? 9.112   -28.255 37.653  1.00 42.97  ? 102 ASP B CB  1 
ATOM   818  C  CG  . ASP A 1 102 ? 8.346   -27.833 36.430  1.00 52.80  ? 102 ASP B CG  1 
ATOM   819  O  OD1 . ASP A 1 102 ? 7.110   -27.648 36.527  1.00 52.54  ? 102 ASP B OD1 1 
ATOM   820  O  OD2 . ASP A 1 102 ? 8.994   -27.659 35.372  1.00 58.87  ? 102 ASP B OD2 1 
ATOM   821  N  N   . LEU A 1 103 ? 9.884   -28.340 40.656  1.00 42.88  ? 103 LEU B N   1 
ATOM   822  C  CA  . LEU A 1 103 ? 10.671  -28.920 41.742  1.00 46.04  ? 103 LEU B CA  1 
ATOM   823  C  C   . LEU A 1 103 ? 9.771   -29.422 42.858  1.00 45.33  ? 103 LEU B C   1 
ATOM   824  O  O   . LEU A 1 103 ? 10.033  -30.475 43.449  1.00 49.57  ? 103 LEU B O   1 
ATOM   825  C  CB  . LEU A 1 103 ? 11.673  -27.911 42.294  1.00 43.78  ? 103 LEU B CB  1 
ATOM   826  C  CG  . LEU A 1 103 ? 12.441  -28.455 43.500  1.00 37.74  ? 103 LEU B CG  1 
ATOM   827  C  CD1 . LEU A 1 103 ? 13.284  -29.629 43.055  1.00 37.96  ? 103 LEU B CD1 1 
ATOM   828  C  CD2 . LEU A 1 103 ? 13.288  -27.384 44.165  1.00 37.27  ? 103 LEU B CD2 1 
ATOM   829  N  N   . GLU A 1 104 ? 8.696   -28.692 43.149  1.00 51.23  ? 104 GLU B N   1 
ATOM   830  C  CA  . GLU A 1 104 ? 7.744   -29.148 44.157  1.00 50.09  ? 104 GLU B CA  1 
ATOM   831  C  C   . GLU A 1 104 ? 7.089   -30.456 43.746  1.00 50.95  ? 104 GLU B C   1 
ATOM   832  O  O   . GLU A 1 104 ? 6.976   -31.384 44.554  1.00 55.06  ? 104 GLU B O   1 
ATOM   833  C  CB  . GLU A 1 104 ? 6.691   -28.074 44.399  1.00 50.38  ? 104 GLU B CB  1 
ATOM   834  C  CG  . GLU A 1 104 ? 7.240   -26.926 45.212  1.00 58.94  ? 104 GLU B CG  1 
ATOM   835  C  CD  . GLU A 1 104 ? 7.581   -27.327 46.640  1.00 65.72  ? 104 GLU B CD  1 
ATOM   836  O  OE1 . GLU A 1 104 ? 8.664   -26.917 47.135  1.00 53.47  ? 104 GLU B OE1 1 
ATOM   837  O  OE2 . GLU A 1 104 ? 6.757   -28.048 47.260  1.00 73.55  ? 104 GLU B OE2 1 
ATOM   838  N  N   . LYS A 1 105 ? 6.646   -30.548 42.488  1.00 52.53  ? 105 LYS B N   1 
ATOM   839  C  CA  . LYS A 1 105 ? 5.994   -31.768 42.025  1.00 48.98  ? 105 LYS B CA  1 
ATOM   840  C  C   . LYS A 1 105 ? 6.963   -32.935 42.024  1.00 53.67  ? 105 LYS B C   1 
ATOM   841  O  O   . LYS A 1 105 ? 6.578   -34.066 42.343  1.00 57.97  ? 105 LYS B O   1 
ATOM   842  C  CB  . LYS A 1 105 ? 5.420   -31.567 40.628  1.00 47.13  ? 105 LYS B CB  1 
ATOM   843  C  CG  . LYS A 1 105 ? 4.110   -30.796 40.588  1.00 50.75  ? 105 LYS B CG  1 
ATOM   844  C  CD  . LYS A 1 105 ? 3.756   -30.483 39.155  1.00 46.73  ? 105 LYS B CD  1 
ATOM   845  C  CE  . LYS A 1 105 ? 2.544   -29.604 39.053  1.00 52.41  ? 105 LYS B CE  1 
ATOM   846  N  NZ  . LYS A 1 105 ? 2.487   -29.060 37.661  1.00 58.91  ? 105 LYS B NZ  1 
ATOM   847  N  N   . GLN A 1 106 ? 8.226   -32.677 41.671  1.00 46.29  ? 106 GLN B N   1 
ATOM   848  C  CA  . GLN A 1 106 ? 9.235   -33.728 41.673  1.00 48.74  ? 106 GLN B CA  1 
ATOM   849  C  C   . GLN A 1 106 ? 9.419   -34.293 43.078  1.00 53.72  ? 106 GLN B C   1 
ATOM   850  O  O   . GLN A 1 106 ? 9.341   -35.509 43.285  1.00 51.76  ? 106 GLN B O   1 
ATOM   851  C  CB  . GLN A 1 106 ? 10.552  -33.176 41.108  1.00 47.96  ? 106 GLN B CB  1 
ATOM   852  C  CG  . GLN A 1 106 ? 11.796  -34.044 41.317  1.00 56.27  ? 106 GLN B CG  1 
ATOM   853  C  CD  . GLN A 1 106 ? 13.052  -33.462 40.649  1.00 66.42  ? 106 GLN B CD  1 
ATOM   854  O  OE1 . GLN A 1 106 ? 13.019  -32.372 40.069  1.00 67.54  ? 106 GLN B OE1 1 
ATOM   855  N  NE2 . GLN A 1 106 ? 14.166  -34.185 40.747  1.00 60.72  ? 106 GLN B NE2 1 
ATOM   856  N  N   . VAL A 1 107 ? 9.630   -33.410 44.062  1.00 54.93  ? 107 VAL B N   1 
ATOM   857  C  CA  . VAL A 1 107 ? 9.798   -33.826 45.455  1.00 48.65  ? 107 VAL B CA  1 
ATOM   858  C  C   . VAL A 1 107 ? 8.587   -34.629 45.929  1.00 54.11  ? 107 VAL B C   1 
ATOM   859  O  O   . VAL A 1 107 ? 8.724   -35.693 46.551  1.00 49.89  ? 107 VAL B O   1 
ATOM   860  C  CB  . VAL A 1 107 ? 10.043  -32.593 46.344  1.00 50.48  ? 107 VAL B CB  1 
ATOM   861  C  CG1 . VAL A 1 107 ? 9.964   -32.948 47.846  1.00 43.55  ? 107 VAL B CG1 1 
ATOM   862  C  CG2 . VAL A 1 107 ? 11.371  -31.948 45.981  1.00 43.63  ? 107 VAL B CG2 1 
ATOM   863  N  N   . ASN A 1 108 ? 7.382   -34.136 45.633  1.00 51.62  ? 108 ASN B N   1 
ATOM   864  C  CA  . ASN A 1 108 ? 6.171   -34.801 46.105  1.00 56.25  ? 108 ASN B CA  1 
ATOM   865  C  C   . ASN A 1 108 ? 5.899   -36.107 45.360  1.00 59.76  ? 108 ASN B C   1 
ATOM   866  O  O   . ASN A 1 108 ? 5.328   -37.038 45.934  1.00 55.29  ? 108 ASN B O   1 
ATOM   867  C  CB  . ASN A 1 108 ? 4.980   -33.858 45.979  1.00 62.67  ? 108 ASN B CB  1 
ATOM   868  C  CG  . ASN A 1 108 ? 4.703   -33.126 47.264  1.00 73.87  ? 108 ASN B CG  1 
ATOM   869  O  OD1 . ASN A 1 108 ? 5.402   -32.169 47.601  1.00 78.91  ? 108 ASN B OD1 1 
ATOM   870  N  ND2 . ASN A 1 108 ? 3.706   -33.596 48.017  1.00 72.56  ? 108 ASN B ND2 1 
ATOM   871  N  N   . GLN A 1 109 ? 6.278   -36.194 44.086  1.00 62.00  ? 109 GLN B N   1 
ATOM   872  C  CA  . GLN A 1 109 ? 6.247   -37.480 43.399  1.00 58.08  ? 109 GLN B CA  1 
ATOM   873  C  C   . GLN A 1 109 ? 7.107   -38.509 44.128  1.00 57.83  ? 109 GLN B C   1 
ATOM   874  O  O   . GLN A 1 109 ? 6.662   -39.626 44.407  1.00 58.09  ? 109 GLN B O   1 
ATOM   875  C  CB  . GLN A 1 109 ? 6.719   -37.307 41.954  1.00 58.35  ? 109 GLN B CB  1 
ATOM   876  C  CG  . GLN A 1 109 ? 6.333   -38.439 41.046  1.00 62.03  ? 109 GLN B CG  1 
ATOM   877  C  CD  . GLN A 1 109 ? 4.829   -38.580 40.949  1.00 75.54  ? 109 GLN B CD  1 
ATOM   878  O  OE1 . GLN A 1 109 ? 4.260   -39.580 41.399  1.00 68.66  ? 109 GLN B OE1 1 
ATOM   879  N  NE2 . GLN A 1 109 ? 4.171   -37.572 40.370  1.00 68.59  ? 109 GLN B NE2 1 
ATOM   880  N  N   . SER A 1 110 ? 8.345   -38.144 44.458  1.00 55.91  ? 110 SER B N   1 
ATOM   881  C  CA  . SER A 1 110 ? 9.215   -39.077 45.165  1.00 53.31  ? 110 SER B CA  1 
ATOM   882  C  C   . SER A 1 110 ? 8.662   -39.430 46.537  1.00 55.66  ? 110 SER B C   1 
ATOM   883  O  O   . SER A 1 110 ? 8.852   -40.556 47.019  1.00 56.65  ? 110 SER B O   1 
ATOM   884  C  CB  . SER A 1 110 ? 10.605  -38.482 45.295  1.00 45.03  ? 110 SER B CB  1 
ATOM   885  O  OG  . SER A 1 110 ? 11.193  -38.925 46.491  1.00 52.62  ? 110 SER B OG  1 
ATOM   886  N  N   . LEU A 1 111 ? 7.980   -38.484 47.180  1.00 53.34  ? 111 LEU B N   1 
ATOM   887  C  CA  . LEU A 1 111 ? 7.306   -38.783 48.435  1.00 54.48  ? 111 LEU B CA  1 
ATOM   888  C  C   . LEU A 1 111 ? 6.174   -39.774 48.215  1.00 56.90  ? 111 LEU B C   1 
ATOM   889  O  O   . LEU A 1 111 ? 5.944   -40.657 49.051  1.00 52.46  ? 111 LEU B O   1 
ATOM   890  C  CB  . LEU A 1 111 ? 6.769   -37.497 49.054  1.00 53.08  ? 111 LEU B CB  1 
ATOM   891  C  CG  . LEU A 1 111 ? 7.666   -36.799 50.065  1.00 58.73  ? 111 LEU B CG  1 
ATOM   892  C  CD1 . LEU A 1 111 ? 7.299   -35.318 50.146  1.00 67.19  ? 111 LEU B CD1 1 
ATOM   893  C  CD2 . LEU A 1 111 ? 7.525   -37.468 51.410  1.00 59.33  ? 111 LEU B CD2 1 
ATOM   894  N  N   . LEU A 1 112 ? 5.449   -39.623 47.100  1.00 53.52  ? 112 LEU B N   1 
ATOM   895  C  CA  . LEU A 1 112 ? 4.380   -40.553 46.759  1.00 52.46  ? 112 LEU B CA  1 
ATOM   896  C  C   . LEU A 1 112 ? 4.918   -41.969 46.614  1.00 57.14  ? 112 LEU B C   1 
ATOM   897  O  O   . LEU A 1 112 ? 4.278   -42.928 47.055  1.00 55.76  ? 112 LEU B O   1 
ATOM   898  C  CB  . LEU A 1 112 ? 3.684   -40.107 45.470  1.00 57.31  ? 112 LEU B CB  1 
ATOM   899  C  CG  . LEU A 1 112 ? 2.286   -39.447 45.479  1.00 69.87  ? 112 LEU B CG  1 
ATOM   900  C  CD1 . LEU A 1 112 ? 1.214   -40.422 45.973  1.00 64.55  ? 112 LEU B CD1 1 
ATOM   901  C  CD2 . LEU A 1 112 ? 2.216   -38.086 46.246  1.00 64.80  ? 112 LEU B CD2 1 
ATOM   902  N  N   . GLU A 1 113 ? 6.105   -42.118 46.014  1.00 56.86  ? 113 GLU B N   1 
ATOM   903  C  CA  . GLU A 1 113 ? 6.663   -43.446 45.793  1.00 58.28  ? 113 GLU B CA  1 
ATOM   904  C  C   . GLU A 1 113 ? 7.091   -44.079 47.103  1.00 57.37  ? 113 GLU B C   1 
ATOM   905  O  O   . GLU A 1 113 ? 6.827   -45.260 47.351  1.00 62.41  ? 113 GLU B O   1 
ATOM   906  C  CB  . GLU A 1 113 ? 7.845   -43.377 44.829  1.00 58.93  ? 113 GLU B CB  1 
ATOM   907  C  CG  . GLU A 1 113 ? 7.459   -43.604 43.384  1.00 72.57  ? 113 GLU B CG  1 
ATOM   908  C  CD  . GLU A 1 113 ? 8.282   -42.758 42.430  1.00 82.75  ? 113 GLU B CD  1 
ATOM   909  O  OE1 . GLU A 1 113 ? 7.694   -42.182 41.477  1.00 76.65  ? 113 GLU B OE1 1 
ATOM   910  O  OE2 . GLU A 1 113 ? 9.516   -42.670 42.644  1.00 84.66  ? 113 GLU B OE2 1 
ATOM   911  N  N   . LEU A 1 114 ? 7.770   -43.310 47.948  1.00 56.87  ? 114 LEU B N   1 
ATOM   912  C  CA  . LEU A 1 114 ? 8.141   -43.829 49.255  1.00 59.99  ? 114 LEU B CA  1 
ATOM   913  C  C   . LEU A 1 114 ? 6.906   -44.192 50.068  1.00 61.38  ? 114 LEU B C   1 
ATOM   914  O  O   . LEU A 1 114 ? 6.945   -45.126 50.876  1.00 63.78  ? 114 LEU B O   1 
ATOM   915  C  CB  . LEU A 1 114 ? 9.028   -42.810 49.971  1.00 50.74  ? 114 LEU B CB  1 
ATOM   916  C  CG  . LEU A 1 114 ? 9.200   -42.846 51.476  1.00 57.98  ? 114 LEU B CG  1 
ATOM   917  C  CD1 . LEU A 1 114 ? 10.139  -43.976 51.863  1.00 62.31  ? 114 LEU B CD1 1 
ATOM   918  C  CD2 . LEU A 1 114 ? 9.812   -41.535 51.881  1.00 51.45  ? 114 LEU B CD2 1 
ATOM   919  N  N   . HIS A 1 115 ? 5.788   -43.503 49.831  1.00 61.56  ? 115 HIS B N   1 
ATOM   920  C  CA  . HIS A 1 115 ? 4.533   -43.912 50.454  1.00 63.66  ? 115 HIS B CA  1 
ATOM   921  C  C   . HIS A 1 115 ? 4.060   -45.271 49.936  1.00 59.61  ? 115 HIS B C   1 
ATOM   922  O  O   . HIS A 1 115 ? 3.408   -46.012 50.675  1.00 55.92  ? 115 HIS B O   1 
ATOM   923  C  CB  . HIS A 1 115 ? 3.461   -42.842 50.234  1.00 52.88  ? 115 HIS B CB  1 
ATOM   924  C  CG  . HIS A 1 115 ? 2.192   -43.107 50.979  1.00 54.22  ? 115 HIS B CG  1 
ATOM   925  N  ND1 . HIS A 1 115 ? 1.267   -44.042 50.565  1.00 52.62  ? 115 HIS B ND1 1 
ATOM   926  C  CD2 . HIS A 1 115 ? 1.699   -42.570 52.121  1.00 55.78  ? 115 HIS B CD2 1 
ATOM   927  C  CE1 . HIS A 1 115 ? 0.260   -44.067 51.419  1.00 55.51  ? 115 HIS B CE1 1 
ATOM   928  N  NE2 . HIS A 1 115 ? 0.495   -43.181 52.370  1.00 53.22  ? 115 HIS B NE2 1 
ATOM   929  N  N   . SER A 1 116 ? 4.386   -45.619 48.684  1.00 60.23  ? 116 SER B N   1 
ATOM   930  C  CA  . SER A 1 116 ? 4.050   -46.945 48.169  1.00 62.24  ? 116 SER B CA  1 
ATOM   931  C  C   . SER A 1 116 ? 4.902   -48.036 48.808  1.00 65.49  ? 116 SER B C   1 
ATOM   932  O  O   . SER A 1 116 ? 4.395   -49.120 49.121  1.00 68.90  ? 116 SER B O   1 
ATOM   933  C  CB  . SER A 1 116 ? 4.197   -46.994 46.647  1.00 56.04  ? 116 SER B CB  1 
ATOM   934  O  OG  . SER A 1 116 ? 2.962   -46.715 46.001  1.00 73.63  ? 116 SER B OG  1 
ATOM   935  N  N   . THR A 1 117 ? 6.197   -47.792 49.000  1.00 60.43  ? 117 THR B N   1 
ATOM   936  C  CA  . THR A 1 117 ? 7.029   -48.859 49.543  1.00 64.97  ? 117 THR B CA  1 
ATOM   937  C  C   . THR A 1 117 ? 6.784   -49.017 51.040  1.00 62.30  ? 117 THR B C   1 
ATOM   938  O  O   . THR A 1 117 ? 6.811   -50.130 51.571  1.00 67.55  ? 117 THR B O   1 
ATOM   939  C  CB  . THR A 1 117 ? 8.513   -48.608 49.233  1.00 64.86  ? 117 THR B CB  1 
ATOM   940  O  OG1 . THR A 1 117 ? 9.072   -47.699 50.189  1.00 70.85  ? 117 THR B OG1 1 
ATOM   941  C  CG2 . THR A 1 117 ? 8.699   -48.052 47.810  1.00 62.81  ? 117 THR B CG2 1 
ATOM   942  N  N   . ALA A 1 118 ? 6.525   -47.910 51.733  1.00 59.34  ? 118 ALA B N   1 
ATOM   943  C  CA  . ALA A 1 118 ? 6.125   -48.003 53.130  1.00 59.34  ? 118 ALA B CA  1 
ATOM   944  C  C   . ALA A 1 118 ? 4.791   -48.734 53.285  1.00 67.26  ? 118 ALA B C   1 
ATOM   945  O  O   . ALA A 1 118 ? 4.605   -49.468 54.262  1.00 67.47  ? 118 ALA B O   1 
ATOM   946  C  CB  . ALA A 1 118 ? 6.060   -46.609 53.747  1.00 63.41  ? 118 ALA B CB  1 
ATOM   947  N  N   . SER A 1 119 ? 3.857   -48.552 52.344  1.00 61.14  ? 119 SER B N   1 
ATOM   948  C  CA  . SER A 1 119 ? 2.669   -49.401 52.309  1.00 61.32  ? 119 SER B CA  1 
ATOM   949  C  C   . SER A 1 119 ? 3.037   -50.844 51.999  1.00 64.82  ? 119 SER B C   1 
ATOM   950  O  O   . SER A 1 119 ? 2.574   -51.772 52.673  1.00 69.03  ? 119 SER B O   1 
ATOM   951  C  CB  . SER A 1 119 ? 1.665   -48.892 51.272  1.00 62.22  ? 119 SER B CB  1 
ATOM   952  O  OG  . SER A 1 119 ? 1.073   -47.670 51.655  1.00 57.09  ? 119 SER B OG  1 
ATOM   953  N  N   . GLY A 1 120 ? 3.874   -51.052 50.980  1.00 69.69  ? 120 GLY B N   1 
ATOM   954  C  CA  . GLY A 1 120 ? 4.217   -52.396 50.542  1.00 69.68  ? 120 GLY B CA  1 
ATOM   955  C  C   . GLY A 1 120 ? 4.923   -53.239 51.585  1.00 68.61  ? 120 GLY B C   1 
ATOM   956  O  O   . GLY A 1 120 ? 5.001   -54.462 51.427  1.00 75.87  ? 120 GLY B O   1 
ATOM   957  N  N   . ASN A 1 121 ? 5.448   -52.614 52.643  1.00 71.95  ? 121 ASN B N   1 
ATOM   958  C  CA  . ASN A 1 121 ? 6.114   -53.302 53.743  1.00 66.61  ? 121 ASN B CA  1 
ATOM   959  C  C   . ASN A 1 121 ? 5.320   -53.205 55.039  1.00 64.25  ? 121 ASN B C   1 
ATOM   960  O  O   . ASN A 1 121 ? 5.871   -53.447 56.116  1.00 53.95  ? 121 ASN B O   1 
ATOM   961  C  CB  . ASN A 1 121 ? 7.522   -52.741 53.948  1.00 62.30  ? 121 ASN B CB  1 
ATOM   962  C  CG  . ASN A 1 121 ? 8.485   -53.179 52.868  1.00 63.80  ? 121 ASN B CG  1 
ATOM   963  O  OD1 . ASN A 1 121 ? 8.887   -54.339 52.814  1.00 71.59  ? 121 ASN B OD1 1 
ATOM   964  N  ND2 . ASN A 1 121 ? 8.867   -52.253 52.003  1.00 65.87  ? 121 ASN B ND2 1 
ATOM   965  N  N   . ASN A 1 122 ? 4.043   -52.830 54.950  1.00 64.90  ? 122 ASN B N   1 
ATOM   966  C  CA  . ASN A 1 122 ? 3.150   -52.735 56.105  1.00 71.09  ? 122 ASN B CA  1 
ATOM   967  C  C   . ASN A 1 122 ? 3.825   -52.026 57.280  1.00 72.75  ? 122 ASN B C   1 
ATOM   968  O  O   . ASN A 1 122 ? 3.727   -52.437 58.441  1.00 74.80  ? 122 ASN B O   1 
ATOM   969  C  CB  . ASN A 1 122 ? 2.621   -54.119 56.497  1.00 77.43  ? 122 ASN B CB  1 
ATOM   970  C  CG  . ASN A 1 122 ? 1.509   -54.603 55.562  1.00 77.88  ? 122 ASN B CG  1 
ATOM   971  O  OD1 . ASN A 1 122 ? 0.942   -53.825 54.789  1.00 75.36  ? 122 ASN B OD1 1 
ATOM   972  N  ND2 . ASN A 1 122 ? 1.205   -55.891 55.626  1.00 79.87  ? 122 ASN B ND2 1 
ATOM   973  N  N   . ASP A 1 123 ? 4.536   -50.957 56.960  1.00 73.21  ? 123 ASP B N   1 
ATOM   974  C  CA  . ASP A 1 123 ? 5.076   -50.027 57.934  1.00 70.08  ? 123 ASP B CA  1 
ATOM   975  C  C   . ASP A 1 123 ? 4.061   -48.909 58.145  1.00 68.11  ? 123 ASP B C   1 
ATOM   976  O  O   . ASP A 1 123 ? 4.200   -47.821 57.571  1.00 68.23  ? 123 ASP B O   1 
ATOM   977  C  CB  . ASP A 1 123 ? 6.416   -49.473 57.454  1.00 65.69  ? 123 ASP B CB  1 
ATOM   978  C  CG  . ASP A 1 123 ? 7.178   -48.770 58.552  1.00 71.33  ? 123 ASP B CG  1 
ATOM   979  O  OD1 . ASP A 1 123 ? 6.600   -48.545 59.651  1.00 62.47  ? 123 ASP B OD1 1 
ATOM   980  O  OD2 . ASP A 1 123 ? 8.362   -48.452 58.305  1.00 78.82  ? 123 ASP B OD2 1 
ATOM   981  N  N   . PRO A 1 124 ? 3.045   -49.126 58.984  1.00 72.36  ? 124 PRO B N   1 
ATOM   982  C  CA  . PRO A 1 124 ? 1.954   -48.148 59.080  1.00 70.77  ? 124 PRO B CA  1 
ATOM   983  C  C   . PRO A 1 124 ? 2.405   -46.812 59.613  1.00 72.61  ? 124 PRO B C   1 
ATOM   984  O  O   . PRO A 1 124 ? 1.641   -45.838 59.534  1.00 78.61  ? 124 PRO B O   1 
ATOM   985  C  CB  . PRO A 1 124 ? 0.975   -48.823 60.044  1.00 68.34  ? 124 PRO B CB  1 
ATOM   986  C  CG  . PRO A 1 124 ? 1.879   -49.546 60.984  1.00 67.55  ? 124 PRO B CG  1 
ATOM   987  C  CD  . PRO A 1 124 ? 3.020   -50.069 60.118  1.00 73.91  ? 124 PRO B CD  1 
ATOM   988  N  N   . CYS A 1 125 ? 3.620   -46.739 60.145  1.00 71.15  ? 125 CYS B N   1 
ATOM   989  C  CA  . CYS A 1 125 ? 4.102   -45.557 60.832  1.00 66.73  ? 125 CYS B CA  1 
ATOM   990  C  C   . CYS A 1 125 ? 4.972   -44.678 59.954  1.00 63.57  ? 125 CYS B C   1 
ATOM   991  O  O   . CYS A 1 125 ? 5.087   -43.475 60.221  1.00 63.50  ? 125 CYS B O   1 
ATOM   992  C  CB  . CYS A 1 125 ? 4.864   -45.992 62.080  1.00 67.72  ? 125 CYS B CB  1 
ATOM   993  S  SG  . CYS A 1 125 ? 3.720   -46.549 63.360  1.00 85.10  ? 125 CYS B SG  1 
ATOM   994  N  N   . LEU A 1 126 ? 5.571   -45.247 58.911  1.00 58.57  ? 126 LEU B N   1 
ATOM   995  C  CA  . LEU A 1 126 ? 6.218   -44.435 57.896  1.00 58.93  ? 126 LEU B CA  1 
ATOM   996  C  C   . LEU A 1 126 ? 5.193   -43.823 56.944  1.00 63.62  ? 126 LEU B C   1 
ATOM   997  O  O   . LEU A 1 126 ? 5.341   -42.669 56.531  1.00 64.04  ? 126 LEU B O   1 
ATOM   998  C  CB  . LEU A 1 126 ? 7.240   -45.272 57.131  1.00 56.44  ? 126 LEU B CB  1 
ATOM   999  C  CG  . LEU A 1 126 ? 7.914   -44.430 56.064  1.00 59.81  ? 126 LEU B CG  1 
ATOM   1000 C  CD1 . LEU A 1 126 ? 8.587   -43.239 56.724  1.00 59.49  ? 126 LEU B CD1 1 
ATOM   1001 C  CD2 . LEU A 1 126 ? 8.921   -45.251 55.284  1.00 67.52  ? 126 LEU B CD2 1 
ATOM   1002 N  N   . THR A 1 127 ? 4.143   -44.570 56.592  1.00 65.95  ? 127 THR B N   1 
ATOM   1003 C  CA  . THR A 1 127 ? 3.053   -43.966 55.829  1.00 66.56  ? 127 THR B CA  1 
ATOM   1004 C  C   . THR A 1 127 ? 2.412   -42.819 56.604  1.00 61.54  ? 127 THR B C   1 
ATOM   1005 O  O   . THR A 1 127 ? 2.141   -41.757 56.036  1.00 64.70  ? 127 THR B O   1 
ATOM   1006 C  CB  . THR A 1 127 ? 1.998   -45.011 55.452  1.00 64.41  ? 127 THR B CB  1 
ATOM   1007 O  OG1 . THR A 1 127 ? 1.299   -45.445 56.626  1.00 66.95  ? 127 THR B OG1 1 
ATOM   1008 C  CG2 . THR A 1 127 ? 2.645   -46.208 54.754  1.00 58.44  ? 127 THR B CG2 1 
ATOM   1009 N  N   . LYS A 1 128 ? 2.180   -43.000 57.906  1.00 60.67  ? 128 LYS B N   1 
ATOM   1010 C  CA  . LYS A 1 128 ? 1.604   -41.904 58.679  1.00 61.59  ? 128 LYS B CA  1 
ATOM   1011 C  C   . LYS A 1 128 ? 2.543   -40.705 58.735  1.00 67.56  ? 128 LYS B C   1 
ATOM   1012 O  O   . LYS A 1 128 ? 2.090   -39.555 58.685  1.00 69.08  ? 128 LYS B O   1 
ATOM   1013 C  CB  . LYS A 1 128 ? 1.254   -42.351 60.094  1.00 69.68  ? 128 LYS B CB  1 
ATOM   1014 C  CG  . LYS A 1 128 ? 0.546   -41.251 60.869  1.00 78.13  ? 128 LYS B CG  1 
ATOM   1015 C  CD  . LYS A 1 128 ? 0.652   -41.452 62.354  1.00 88.63  ? 128 LYS B CD  1 
ATOM   1016 C  CE  . LYS A 1 128 ? 2.088   -41.721 62.755  1.00 94.03  ? 128 LYS B CE  1 
ATOM   1017 N  NZ  . LYS A 1 128 ? 2.124   -42.797 63.775  1.00 90.48  ? 128 LYS B NZ  1 
ATOM   1018 N  N   . LEU A 1 129 ? 3.855   -40.944 58.847  1.00 65.81  ? 129 LEU B N   1 
ATOM   1019 C  CA  . LEU A 1 129 ? 4.789   -39.826 58.768  1.00 65.94  ? 129 LEU B CA  1 
ATOM   1020 C  C   . LEU A 1 129 ? 4.702   -39.133 57.415  1.00 69.34  ? 129 LEU B C   1 
ATOM   1021 O  O   . LEU A 1 129 ? 4.635   -37.899 57.350  1.00 68.49  ? 129 LEU B O   1 
ATOM   1022 C  CB  . LEU A 1 129 ? 6.219   -40.288 59.024  1.00 65.33  ? 129 LEU B CB  1 
ATOM   1023 C  CG  . LEU A 1 129 ? 7.214   -39.189 58.647  1.00 57.12  ? 129 LEU B CG  1 
ATOM   1024 C  CD1 . LEU A 1 129 ? 7.053   -37.981 59.555  1.00 50.30  ? 129 LEU B CD1 1 
ATOM   1025 C  CD2 . LEU A 1 129 ? 8.619   -39.724 58.709  1.00 58.74  ? 129 LEU B CD2 1 
ATOM   1026 N  N   . LEU A 1 130 ? 4.672   -39.917 56.329  1.00 62.67  ? 130 LEU B N   1 
ATOM   1027 C  CA  . LEU A 1 130 ? 4.717   -39.351 54.986  1.00 66.03  ? 130 LEU B CA  1 
ATOM   1028 C  C   . LEU A 1 130 ? 3.536   -38.446 54.691  1.00 74.12  ? 130 LEU B C   1 
ATOM   1029 O  O   . LEU A 1 130 ? 3.654   -37.529 53.874  1.00 82.60  ? 130 LEU B O   1 
ATOM   1030 C  CB  . LEU A 1 130 ? 4.782   -40.460 53.945  1.00 63.27  ? 130 LEU B CB  1 
ATOM   1031 C  CG  . LEU A 1 130 ? 6.139   -41.128 54.010  1.00 60.43  ? 130 LEU B CG  1 
ATOM   1032 C  CD1 . LEU A 1 130 ? 6.168   -42.383 53.191  1.00 61.38  ? 130 LEU B CD1 1 
ATOM   1033 C  CD2 . LEU A 1 130 ? 7.186   -40.115 53.589  1.00 66.42  ? 130 LEU B CD2 1 
ATOM   1034 N  N   . GLU A 1 131 ? 2.394   -38.678 55.318  1.00 72.24  ? 131 GLU B N   1 
ATOM   1035 C  CA  . GLU A 1 131 ? 1.299   -37.781 55.007  1.00 76.98  ? 131 GLU B CA  1 
ATOM   1036 C  C   . GLU A 1 131 ? 1.142   -36.691 56.057  1.00 79.74  ? 131 GLU B C   1 
ATOM   1037 O  O   . GLU A 1 131 ? 1.038   -35.513 55.700  1.00 89.09  ? 131 GLU B O   1 
ATOM   1038 C  CB  . GLU A 1 131 ? 0.004   -38.574 54.816  1.00 88.55  ? 131 GLU B CB  1 
ATOM   1039 C  CG  . GLU A 1 131 ? -0.393  -39.617 55.875  1.00 82.11  ? 131 GLU B CG  1 
ATOM   1040 C  CD  . GLU A 1 131 ? -1.065  -40.836 55.227  1.00 79.93  ? 131 GLU B CD  1 
ATOM   1041 O  OE1 . GLU A 1 131 ? -1.981  -41.437 55.828  1.00 82.07  ? 131 GLU B OE1 1 
ATOM   1042 O  OE2 . GLU A 1 131 ? -0.653  -41.195 54.105  1.00 78.32  ? 131 GLU B OE2 1 
ATOM   1043 N  N   . ASP A 1 132 ? 1.167   -37.064 57.344  1.00 77.12  ? 132 ASP B N   1 
ATOM   1044 C  CA  . ASP A 1 132 ? 1.050   -36.085 58.428  1.00 81.07  ? 132 ASP B CA  1 
ATOM   1045 C  C   . ASP A 1 132 ? 1.956   -34.873 58.234  1.00 90.28  ? 132 ASP B C   1 
ATOM   1046 O  O   . ASP A 1 132 ? 1.601   -33.763 58.650  1.00 92.01  ? 132 ASP B O   1 
ATOM   1047 C  CB  . ASP A 1 132 ? 1.366   -36.722 59.787  1.00 75.23  ? 132 ASP B CB  1 
ATOM   1048 C  CG  . ASP A 1 132 ? 0.144   -37.312 60.460  1.00 89.24  ? 132 ASP B CG  1 
ATOM   1049 O  OD1 . ASP A 1 132 ? 0.308   -38.133 61.396  1.00 93.26  ? 132 ASP B OD1 1 
ATOM   1050 O  OD2 . ASP A 1 132 ? -0.987  -36.967 60.048  1.00 95.53  ? 132 ASP B OD2 1 
ATOM   1051 N  N   . GLU A 1 133 ? 3.127   -35.055 57.616  1.00 89.66  ? 133 GLU B N   1 
ATOM   1052 C  CA  . GLU A 1 133 ? 3.980   -33.922 57.277  1.00 87.01  ? 133 GLU B CA  1 
ATOM   1053 C  C   . GLU A 1 133 ? 3.813   -33.454 55.834  1.00 89.41  ? 133 GLU B C   1 
ATOM   1054 O  O   . GLU A 1 133 ? 4.106   -32.284 55.546  1.00 92.47  ? 133 GLU B O   1 
ATOM   1055 C  CB  . GLU A 1 133 ? 5.458   -34.262 57.550  1.00 87.12  ? 133 GLU B CB  1 
ATOM   1056 C  CG  . GLU A 1 133 ? 6.439   -33.128 57.218  1.00 86.78  ? 133 GLU B CG  1 
ATOM   1057 C  CD  . GLU A 1 133 ? 7.393   -32.789 58.345  1.00 87.45  ? 133 GLU B CD  1 
ATOM   1058 O  OE1 . GLU A 1 133 ? 8.539   -32.359 58.052  1.00 75.50  ? 133 GLU B OE1 1 
ATOM   1059 O  OE2 . GLU A 1 133 ? 6.988   -32.936 59.519  1.00 91.12  ? 133 GLU B OE2 1 
ATOM   1060 N  N   . TYR A 1 134 ? 3.311   -34.302 54.925  1.00 88.05  ? 134 TYR B N   1 
ATOM   1061 C  CA  . TYR A 1 134 ? 3.457   -33.951 53.515  1.00 87.38  ? 134 TYR B CA  1 
ATOM   1062 C  C   . TYR A 1 134 ? 2.192   -33.947 52.671  1.00 93.38  ? 134 TYR B C   1 
ATOM   1063 O  O   . TYR A 1 134 ? 2.136   -33.198 51.692  1.00 99.48  ? 134 TYR B O   1 
ATOM   1064 C  CB  . TYR A 1 134 ? 4.486   -34.864 52.870  1.00 80.21  ? 134 TYR B CB  1 
ATOM   1065 C  CG  . TYR A 1 134 ? 5.851   -34.508 53.366  1.00 84.62  ? 134 TYR B CG  1 
ATOM   1066 C  CD1 . TYR A 1 134 ? 6.512   -33.387 52.879  1.00 86.20  ? 134 TYR B CD1 1 
ATOM   1067 C  CD2 . TYR A 1 134 ? 6.454   -35.245 54.374  1.00 82.77  ? 134 TYR B CD2 1 
ATOM   1068 C  CE1 . TYR A 1 134 ? 7.762   -33.037 53.346  1.00 84.44  ? 134 TYR B CE1 1 
ATOM   1069 C  CE2 . TYR A 1 134 ? 7.701   -34.904 54.851  1.00 84.33  ? 134 TYR B CE2 1 
ATOM   1070 C  CZ  . TYR A 1 134 ? 8.350   -33.795 54.340  1.00 80.00  ? 134 TYR B CZ  1 
ATOM   1071 O  OH  . TYR A 1 134 ? 9.589   -33.448 54.821  1.00 75.77  ? 134 TYR B OH  1 
ATOM   1072 N  N   . CYS A 1 135 ? 1.177   -34.757 52.977  1.00 93.86  ? 135 CYS B N   1 
ATOM   1073 C  CA  . CYS A 1 135 ? -0.036  -34.561 52.187  1.00 94.72  ? 135 CYS B CA  1 
ATOM   1074 C  C   . CYS A 1 135 ? -0.704  -33.241 52.518  1.00 94.71  ? 135 CYS B C   1 
ATOM   1075 O  O   . CYS A 1 135 ? -1.213  -32.571 51.616  1.00 92.71  ? 135 CYS B O   1 
ATOM   1076 C  CB  . CYS A 1 135 ? -1.063  -35.689 52.333  1.00 85.89  ? 135 CYS B CB  1 
ATOM   1077 S  SG  . CYS A 1 135 ? -2.239  -35.693 50.865  1.00 98.88  ? 135 CYS B SG  1 
ATOM   1078 N  N   . GLU A 1 136 ? -0.689  -32.829 53.781  1.00 96.41  ? 136 GLU B N   1 
ATOM   1079 C  CA  . GLU A 1 136 ? -1.568  -31.728 54.154  1.00 102.94 ? 136 GLU B CA  1 
ATOM   1080 C  C   . GLU A 1 136 ? -1.011  -30.373 53.713  1.00 102.73 ? 136 GLU B C   1 
ATOM   1081 O  O   . GLU A 1 136 ? -1.755  -29.536 53.188  1.00 99.42  ? 136 GLU B O   1 
ATOM   1082 C  CB  . GLU A 1 136 ? -1.866  -31.780 55.662  1.00 105.18 ? 136 GLU B CB  1 
ATOM   1083 C  CG  . GLU A 1 136 ? -0.708  -32.190 56.584  1.00 102.82 ? 136 GLU B CG  1 
ATOM   1084 C  CD  . GLU A 1 136 ? 0.391   -31.142 56.663  1.00 107.53 ? 136 GLU B CD  1 
ATOM   1085 O  OE1 . GLU A 1 136 ? 0.083   -29.941 56.502  1.00 110.75 ? 136 GLU B OE1 1 
ATOM   1086 O  OE2 . GLU A 1 136 ? 1.560   -31.510 56.901  1.00 105.01 ? 136 GLU B OE2 1 
ATOM   1087 N  N   . GLU A 1 137 ? 0.290   -30.139 53.879  1.00 99.34  ? 137 GLU B N   1 
ATOM   1088 C  CA  . GLU A 1 137 ? 0.819   -28.830 53.514  1.00 99.78  ? 137 GLU B CA  1 
ATOM   1089 C  C   . GLU A 1 137 ? 1.404   -28.789 52.111  1.00 95.28  ? 137 GLU B C   1 
ATOM   1090 O  O   . GLU A 1 137 ? 1.331   -27.739 51.461  1.00 96.13  ? 137 GLU B O   1 
ATOM   1091 C  CB  . GLU A 1 137 ? 1.885   -28.355 54.517  1.00 101.32 ? 137 GLU B CB  1 
ATOM   1092 C  CG  . GLU A 1 137 ? 1.748   -26.862 54.913  1.00 103.55 ? 137 GLU B CG  1 
ATOM   1093 C  CD  . GLU A 1 137 ? 2.308   -25.891 53.862  1.00 98.02  ? 137 GLU B CD  1 
ATOM   1094 O  OE1 . GLU A 1 137 ? 1.499   -25.144 53.248  1.00 87.78  ? 137 GLU B OE1 1 
ATOM   1095 O  OE2 . GLU A 1 137 ? 3.548   -25.872 53.657  1.00 86.57  ? 137 GLU B OE2 1 
ATOM   1096 N  N   . GLN A 1 138 ? 1.986   -29.888 51.620  1.00 91.79  ? 138 GLN B N   1 
ATOM   1097 C  CA  . GLN A 1 138 ? 2.523   -29.848 50.265  1.00 89.25  ? 138 GLN B CA  1 
ATOM   1098 C  C   . GLN A 1 138 ? 1.403   -29.715 49.238  1.00 84.53  ? 138 GLN B C   1 
ATOM   1099 O  O   . GLN A 1 138 ? 1.600   -29.098 48.186  1.00 77.86  ? 138 GLN B O   1 
ATOM   1100 C  CB  . GLN A 1 138 ? 3.392   -31.078 49.990  1.00 85.06  ? 138 GLN B CB  1 
ATOM   1101 C  CG  . GLN A 1 138 ? 4.645   -31.161 50.861  1.00 90.68  ? 138 GLN B CG  1 
ATOM   1102 C  CD  . GLN A 1 138 ? 5.466   -29.871 50.850  1.00 92.55  ? 138 GLN B CD  1 
ATOM   1103 O  OE1 . GLN A 1 138 ? 5.539   -29.154 51.857  1.00 90.29  ? 138 GLN B OE1 1 
ATOM   1104 N  NE2 . GLN A 1 138 ? 6.090   -29.574 49.710  1.00 91.52  ? 138 GLN B NE2 1 
ATOM   1105 N  N   . CYS A 1 139 ? 0.219   -30.256 49.540  1.00 81.91  ? 139 CYS B N   1 
ATOM   1106 C  CA  . CYS A 1 139 ? -0.965  -29.952 48.749  1.00 75.05  ? 139 CYS B CA  1 
ATOM   1107 C  C   . CYS A 1 139 ? -1.284  -28.457 48.738  1.00 79.04  ? 139 CYS B C   1 
ATOM   1108 O  O   . CYS A 1 139 ? -1.927  -27.988 47.794  1.00 83.05  ? 139 CYS B O   1 
ATOM   1109 C  CB  . CYS A 1 139 ? -2.154  -30.774 49.279  1.00 90.03  ? 139 CYS B CB  1 
ATOM   1110 S  SG  . CYS A 1 139 ? -3.877  -30.160 49.021  1.00 88.21  ? 139 CYS B SG  1 
ATOM   1111 N  N   . ASP A 1 140 ? -0.841  -27.688 49.745  1.00 81.98  ? 140 ASP B N   1 
ATOM   1112 C  CA  . ASP A 1 140 ? -1.069  -26.241 49.771  1.00 79.17  ? 140 ASP B CA  1 
ATOM   1113 C  C   . ASP A 1 140 ? 0.173   -25.397 49.488  1.00 72.22  ? 140 ASP B C   1 
ATOM   1114 O  O   . ASP A 1 140 ? 0.029   -24.209 49.172  1.00 66.08  ? 140 ASP B O   1 
ATOM   1115 C  CB  . ASP A 1 140 ? -1.679  -25.809 51.106  1.00 82.06  ? 140 ASP B CB  1 
ATOM   1116 C  CG  . ASP A 1 140 ? -3.022  -26.457 51.358  1.00 93.22  ? 140 ASP B CG  1 
ATOM   1117 O  OD1 . ASP A 1 140 ? -3.389  -27.368 50.586  1.00 93.89  ? 140 ASP B OD1 1 
ATOM   1118 O  OD2 . ASP A 1 140 ? -3.727  -26.039 52.303  1.00 97.22  ? 140 ASP B OD2 1 
ATOM   1119 N  N   . SER A 1 141 ? 1.380   -25.958 49.612  1.00 70.77  ? 141 SER B N   1 
ATOM   1120 C  CA  A SER A 1 141 ? 2.556   -25.289 49.062  0.73 69.95  ? 141 SER B CA  1 
ATOM   1121 C  CA  B SER A 1 141 ? 2.557   -25.291 49.060  0.27 70.23  ? 141 SER B CA  1 
ATOM   1122 C  C   . SER A 1 141 ? 2.551   -25.332 47.535  1.00 64.23  ? 141 SER B C   1 
ATOM   1123 O  O   . SER A 1 141 ? 2.984   -24.375 46.885  1.00 55.37  ? 141 SER B O   1 
ATOM   1124 C  CB  A SER A 1 141 ? 3.834   -25.925 49.614  0.73 73.68  ? 141 SER B CB  1 
ATOM   1125 C  CB  B SER A 1 141 ? 3.838   -25.931 49.600  0.27 73.57  ? 141 SER B CB  1 
ATOM   1126 O  OG  A SER A 1 141 ? 4.995   -25.336 49.057  0.73 67.42  ? 141 SER B OG  1 
ATOM   1127 O  OG  B SER A 1 141 ? 4.174   -25.423 50.880  0.27 76.41  ? 141 SER B OG  1 
ATOM   1128 N  N   . ILE A 1 142 ? 2.052   -26.419 46.946  1.00 63.04  ? 142 ILE B N   1 
ATOM   1129 C  CA  . ILE A 1 142 ? 1.963   -26.479 45.494  1.00 60.14  ? 142 ILE B CA  1 
ATOM   1130 C  C   . ILE A 1 142 ? 0.798   -25.634 44.990  1.00 55.39  ? 142 ILE B C   1 
ATOM   1131 O  O   . ILE A 1 142 ? 0.882   -25.028 43.916  1.00 51.60  ? 142 ILE B O   1 
ATOM   1132 C  CB  . ILE A 1 142 ? 1.865   -27.942 45.028  1.00 60.81  ? 142 ILE B CB  1 
ATOM   1133 C  CG1 . ILE A 1 142 ? 3.233   -28.621 45.187  1.00 64.59  ? 142 ILE B CG1 1 
ATOM   1134 C  CG2 . ILE A 1 142 ? 1.346   -28.027 43.589  1.00 55.08  ? 142 ILE B CG2 1 
ATOM   1135 C  CD1 . ILE A 1 142 ? 3.277   -30.066 44.750  1.00 68.03  ? 142 ILE B CD1 1 
ATOM   1136 N  N   . LYS A 1 143 ? -0.293  -25.542 45.744  1.00 58.69  ? 143 LYS B N   1 
ATOM   1137 C  CA  . LYS A 1 143 ? -1.338  -24.628 45.302  1.00 60.10  ? 143 LYS B CA  1 
ATOM   1138 C  C   . LYS A 1 143 ? -0.887  -23.182 45.423  1.00 49.92  ? 143 LYS B C   1 
ATOM   1139 O  O   . LYS A 1 143 ? -1.273  -22.351 44.595  1.00 49.58  ? 143 LYS B O   1 
ATOM   1140 C  CB  . LYS A 1 143 ? -2.633  -24.837 46.082  1.00 58.47  ? 143 LYS B CB  1 
ATOM   1141 C  CG  . LYS A 1 143 ? -3.865  -24.490 45.248  1.00 64.26  ? 143 LYS B CG  1 
ATOM   1142 C  CD  . LYS A 1 143 ? -4.574  -23.242 45.757  1.00 56.53  ? 143 LYS B CD  1 
ATOM   1143 C  CE  . LYS A 1 143 ? -5.915  -23.041 45.050  1.00 56.02  ? 143 LYS B CE  1 
ATOM   1144 N  NZ  . LYS A 1 143 ? -6.824  -22.187 45.875  1.00 53.55  ? 143 LYS B NZ  1 
ATOM   1145 N  N   . LYS A 1 144 ? -0.060  -22.877 46.427  1.00 47.13  ? 144 LYS B N   1 
ATOM   1146 C  CA  . LYS A 1 144 ? 0.412   -21.514 46.636  1.00 50.82  ? 144 LYS B CA  1 
ATOM   1147 C  C   . LYS A 1 144 ? 1.277   -21.031 45.470  1.00 47.95  ? 144 LYS B C   1 
ATOM   1148 O  O   . LYS A 1 144 ? 1.048   -19.943 44.924  1.00 42.64  ? 144 LYS B O   1 
ATOM   1149 C  CB  . LYS A 1 144 ? 1.174   -21.435 47.954  1.00 50.59  ? 144 LYS B CB  1 
ATOM   1150 C  CG  . LYS A 1 144 ? 1.652   -20.030 48.279  1.00 59.88  ? 144 LYS B CG  1 
ATOM   1151 C  CD  . LYS A 1 144 ? 2.721   -20.000 49.379  1.00 62.11  ? 144 LYS B CD  1 
ATOM   1152 C  CE  . LYS A 1 144 ? 2.777   -18.615 50.023  1.00 70.14  ? 144 LYS B CE  1 
ATOM   1153 N  NZ  . LYS A 1 144 ? 1.927   -17.606 49.279  1.00 73.10  ? 144 LYS B NZ  1 
ATOM   1154 N  N   . ILE A 1 145 ? 2.268   -21.835 45.068  1.00 48.01  ? 145 ILE B N   1 
ATOM   1155 C  CA  . ILE A 1 145 ? 3.061   -21.527 43.880  1.00 44.50  ? 145 ILE B CA  1 
ATOM   1156 C  C   . ILE A 1 145 ? 2.159   -21.437 42.661  1.00 40.19  ? 145 ILE B C   1 
ATOM   1157 O  O   . ILE A 1 145 ? 2.297   -20.526 41.832  1.00 39.89  ? 145 ILE B O   1 
ATOM   1158 C  CB  . ILE A 1 145 ? 4.167   -22.584 43.683  1.00 40.89  ? 145 ILE B CB  1 
ATOM   1159 C  CG1 . ILE A 1 145 ? 5.191   -22.485 44.793  1.00 40.21  ? 145 ILE B CG1 1 
ATOM   1160 C  CG2 . ILE A 1 145 ? 4.869   -22.421 42.338  1.00 32.54  ? 145 ILE B CG2 1 
ATOM   1161 C  CD1 . ILE A 1 145 ? 5.933   -23.746 45.005  1.00 48.20  ? 145 ILE B CD1 1 
ATOM   1162 N  N   . GLY A 1 146 ? 1.225   -22.380 42.531  1.00 42.96  ? 146 GLY B N   1 
ATOM   1163 C  CA  . GLY A 1 146 ? 0.271   -22.313 41.434  1.00 44.07  ? 146 GLY B CA  1 
ATOM   1164 C  C   . GLY A 1 146 ? -0.456  -20.983 41.386  1.00 43.90  ? 146 GLY B C   1 
ATOM   1165 O  O   . GLY A 1 146 ? -0.548  -20.342 40.337  1.00 41.46  ? 146 GLY B O   1 
ATOM   1166 N  N   . CYS A 1 147 ? -0.961  -20.533 42.533  1.00 44.24  ? 147 CYS B N   1 
ATOM   1167 C  CA  . CYS A 1 147 ? -1.680  -19.269 42.556  1.00 39.59  ? 147 CYS B CA  1 
ATOM   1168 C  C   . CYS A 1 147 ? -0.761  -18.111 42.213  1.00 43.80  ? 147 CYS B C   1 
ATOM   1169 O  O   . CYS A 1 147 ? -1.160  -17.195 41.481  1.00 39.46  ? 147 CYS B O   1 
ATOM   1170 C  CB  . CYS A 1 147 ? -2.327  -19.055 43.920  1.00 41.75  ? 147 CYS B CB  1 
ATOM   1171 S  SG  . CYS A 1 147 ? -4.040  -19.489 43.930  1.00 61.38  ? 147 CYS B SG  1 
ATOM   1172 N  N   . MET A 1 148 ? 0.480   -18.143 42.723  1.00 41.14  ? 148 MET B N   1 
ATOM   1173 C  CA  . MET A 1 148 ? 1.453   -17.104 42.402  1.00 41.22  ? 148 MET B CA  1 
ATOM   1174 C  C   . MET A 1 148 ? 1.639   -16.977 40.899  1.00 39.40  ? 148 MET B C   1 
ATOM   1175 O  O   . MET A 1 148 ? 1.616   -15.868 40.348  1.00 40.72  ? 148 MET B O   1 
ATOM   1176 C  CB  . MET A 1 148 ? 2.780   -17.406 43.101  1.00 42.31  ? 148 MET B CB  1 
ATOM   1177 C  CG  . MET A 1 148 ? 2.671   -17.338 44.625  1.00 34.99  ? 148 MET B CG  1 
ATOM   1178 S  SD  . MET A 1 148 ? 4.146   -17.827 45.532  1.00 39.82  ? 148 MET B SD  1 
ATOM   1179 C  CE  . MET A 1 148 ? 5.301   -16.526 45.112  1.00 33.95  ? 148 MET B CE  1 
ATOM   1180 N  N   . ILE A 1 149 ? 1.810   -18.108 40.214  1.00 38.02  ? 149 ILE B N   1 
ATOM   1181 C  CA  . ILE A 1 149 ? 1.927   -18.087 38.759  1.00 37.97  ? 149 ILE B CA  1 
ATOM   1182 C  C   . ILE A 1 149 ? 0.702   -17.435 38.132  1.00 40.64  ? 149 ILE B C   1 
ATOM   1183 O  O   . ILE A 1 149 ? 0.819   -16.545 37.279  1.00 41.60  ? 149 ILE B O   1 
ATOM   1184 C  CB  . ILE A 1 149 ? 2.143   -19.511 38.226  1.00 40.04  ? 149 ILE B CB  1 
ATOM   1185 C  CG1 . ILE A 1 149 ? 3.515   -20.027 38.667  1.00 37.77  ? 149 ILE B CG1 1 
ATOM   1186 C  CG2 . ILE A 1 149 ? 1.960   -19.553 36.722  1.00 31.29  ? 149 ILE B CG2 1 
ATOM   1187 C  CD1 . ILE A 1 149 ? 3.630   -21.539 38.631  1.00 40.88  ? 149 ILE B CD1 1 
ATOM   1188 N  N   . THR A 1 150 ? -0.496  -17.870 38.537  1.00 39.57  ? 150 THR B N   1 
ATOM   1189 C  CA  . THR A 1 150 ? -1.710  -17.267 37.991  1.00 39.12  ? 150 THR B CA  1 
ATOM   1190 C  C   . THR A 1 150 ? -1.748  -15.759 38.239  1.00 39.91  ? 150 THR B C   1 
ATOM   1191 O  O   . THR A 1 150 ? -2.135  -14.981 37.359  1.00 41.98  ? 150 THR B O   1 
ATOM   1192 C  CB  . THR A 1 150 ? -2.941  -17.929 38.595  1.00 38.79  ? 150 THR B CB  1 
ATOM   1193 O  OG1 . THR A 1 150 ? -2.891  -19.338 38.362  1.00 34.53  ? 150 THR B OG1 1 
ATOM   1194 C  CG2 . THR A 1 150 ? -4.217  -17.345 37.976  1.00 35.80  ? 150 THR B CG2 1 
ATOM   1195 N  N   . LYS A 1 151 ? -1.344  -15.324 39.430  1.00 39.75  ? 151 LYS B N   1 
ATOM   1196 C  CA  . LYS A 1 151 ? -1.400  -13.901 39.729  1.00 39.32  ? 151 LYS B CA  1 
ATOM   1197 C  C   . LYS A 1 151 ? -0.369  -13.133 38.909  1.00 44.09  ? 151 LYS B C   1 
ATOM   1198 O  O   . LYS A 1 151 ? -0.672  -12.067 38.359  1.00 39.53  ? 151 LYS B O   1 
ATOM   1199 C  CB  . LYS A 1 151 ? -1.201  -13.675 41.226  1.00 37.45  ? 151 LYS B CB  1 
ATOM   1200 C  CG  . LYS A 1 151 ? -1.076  -12.210 41.597  1.00 50.11  ? 151 LYS B CG  1 
ATOM   1201 C  CD  . LYS A 1 151 ? -1.099  -11.996 43.116  1.00 47.28  ? 151 LYS B CD  1 
ATOM   1202 C  CE  . LYS A 1 151 ? -0.759  -10.539 43.458  1.00 53.24  ? 151 LYS B CE  1 
ATOM   1203 N  NZ  . LYS A 1 151 ? -0.176  -10.397 44.818  1.00 56.88  ? 151 LYS B NZ  1 
ATOM   1204 N  N   . LEU A 1 152 ? 0.846   -13.673 38.788  1.00 38.43  ? 152 LEU B N   1 
ATOM   1205 C  CA  . LEU A 1 152 ? 1.867   -12.990 38.006  1.00 37.12  ? 152 LEU B CA  1 
ATOM   1206 C  C   . LEU A 1 152 ? 1.485   -12.926 36.538  1.00 41.60  ? 152 LEU B C   1 
ATOM   1207 O  O   . LEU A 1 152 ? 1.784   -11.937 35.859  1.00 42.39  ? 152 LEU B O   1 
ATOM   1208 C  CB  . LEU A 1 152 ? 3.215   -13.688 38.193  1.00 40.81  ? 152 LEU B CB  1 
ATOM   1209 C  CG  . LEU A 1 152 ? 4.472   -12.984 37.712  1.00 39.34  ? 152 LEU B CG  1 
ATOM   1210 C  CD1 . LEU A 1 152 ? 4.371   -11.521 38.020  1.00 41.88  ? 152 LEU B CD1 1 
ATOM   1211 C  CD2 . LEU A 1 152 ? 5.698   -13.596 38.370  1.00 39.52  ? 152 LEU B CD2 1 
ATOM   1212 N  N   . LYS A 1 153 ? 0.794   -13.944 36.031  1.00 44.47  ? 153 LYS B N   1 
ATOM   1213 C  CA  . LYS A 1 153 ? 0.348   -13.874 34.643  1.00 44.43  ? 153 LYS B CA  1 
ATOM   1214 C  C   . LYS A 1 153 ? -0.746  -12.822 34.464  1.00 45.38  ? 153 LYS B C   1 
ATOM   1215 O  O   . LYS A 1 153 ? -0.786  -12.128 33.440  1.00 45.84  ? 153 LYS B O   1 
ATOM   1216 C  CB  . LYS A 1 153 ? -0.119  -15.248 34.177  1.00 34.76  ? 153 LYS B CB  1 
ATOM   1217 C  CG  . LYS A 1 153 ? 1.020   -16.193 33.911  1.00 39.31  ? 153 LYS B CG  1 
ATOM   1218 C  CD  . LYS A 1 153 ? 0.540   -17.495 33.281  1.00 37.18  ? 153 LYS B CD  1 
ATOM   1219 C  CE  . LYS A 1 153 ? 1.740   -18.411 33.001  1.00 41.59  ? 153 LYS B CE  1 
ATOM   1220 N  NZ  . LYS A 1 153 ? 1.357   -19.759 32.467  1.00 58.01  ? 153 LYS B NZ  1 
ATOM   1221 N  N   . ARG A 1 154 ? -1.637  -12.680 35.447  1.00 42.15  ? 154 ARG B N   1 
ATOM   1222 C  CA  . ARG A 1 154 ? -2.690  -11.676 35.336  1.00 47.04  ? 154 ARG B CA  1 
ATOM   1223 C  C   . ARG A 1 154 ? -2.111  -10.273 35.429  1.00 47.77  ? 154 ARG B C   1 
ATOM   1224 O  O   . ARG A 1 154 ? -2.400  -9.417  34.584  1.00 44.13  ? 154 ARG B O   1 
ATOM   1225 C  CB  . ARG A 1 154 ? -3.754  -11.875 36.421  1.00 39.02  ? 154 ARG B CB  1 
ATOM   1226 C  CG  . ARG A 1 154 ? -4.628  -10.633 36.644  1.00 42.59  ? 154 ARG B CG  1 
ATOM   1227 C  CD  . ARG A 1 154 ? -5.699  -10.829 37.739  1.00 46.88  ? 154 ARG B CD  1 
ATOM   1228 N  NE  . ARG A 1 154 ? -6.511  -12.009 37.460  1.00 35.57  ? 154 ARG B NE  1 
ATOM   1229 C  CZ  . ARG A 1 154 ? -6.393  -13.148 38.124  1.00 45.86  ? 154 ARG B CZ  1 
ATOM   1230 N  NH1 . ARG A 1 154 ? -5.517  -13.245 39.138  1.00 44.71  ? 154 ARG B NH1 1 
ATOM   1231 N  NH2 . ARG A 1 154 ? -7.159  -14.181 37.788  1.00 44.19  ? 154 ARG B NH2 1 
ATOM   1232 N  N   . CYS A 1 155 ? -1.287  -10.025 36.455  1.00 43.74  ? 155 CYS B N   1 
ATOM   1233 C  CA  . CYS A 1 155 ? -0.742  -8.704  36.747  1.00 49.26  ? 155 CYS B CA  1 
ATOM   1234 C  C   . CYS A 1 155 ? 0.165   -8.276  35.605  1.00 53.60  ? 155 CYS B C   1 
ATOM   1235 O  O   . CYS A 1 155 ? 0.609   -7.126  35.562  1.00 51.81  ? 155 CYS B O   1 
ATOM   1236 C  CB  . CYS A 1 155 ? 0.017   -8.690  38.091  1.00 47.59  ? 155 CYS B CB  1 
ATOM   1237 S  SG  . CYS A 1 155 ? -1.049  -8.684  39.597  1.00 70.68  ? 155 CYS B SG  1 
ATOM   1238 N  N   . GLY A 1 156 ? 0.368   -9.178  34.637  1.00 59.84  ? 156 GLY B N   1 
ATOM   1239 C  CA  . GLY A 1 156 ? 1.310   -8.988  33.561  1.00 48.98  ? 156 GLY B CA  1 
ATOM   1240 C  C   . GLY A 1 156 ? 2.642   -9.434  34.099  1.00 56.29  ? 156 GLY B C   1 
ATOM   1241 O  O   . GLY A 1 156 ? 3.116   -8.922  35.120  1.00 60.61  ? 156 GLY B O   1 
ATOM   1242 N  N   . PRO A 1 157 ? 3.246   -10.447 33.469  1.00 55.66  ? 157 PRO B N   1 
ATOM   1243 C  CA  . PRO A 1 157 ? 4.400   -11.116 34.101  1.00 49.84  ? 157 PRO B CA  1 
ATOM   1244 C  C   . PRO A 1 157 ? 5.682   -10.296 34.083  1.00 51.41  ? 157 PRO B C   1 
ATOM   1245 O  O   . PRO A 1 157 ? 6.628   -10.657 34.791  1.00 56.25  ? 157 PRO B O   1 
ATOM   1246 C  CB  . PRO A 1 157 ? 4.557   -12.409 33.283  1.00 50.24  ? 157 PRO B CB  1 
ATOM   1247 C  CG  . PRO A 1 157 ? 3.354   -12.457 32.343  1.00 50.78  ? 157 PRO B CG  1 
ATOM   1248 C  CD  . PRO A 1 157 ? 2.895   -11.044 32.173  1.00 49.76  ? 157 PRO B CD  1 
ATOM   1249 N  N   . THR A 1 158 ? 5.745   -9.209  33.316  1.00 53.32  ? 158 THR B N   1 
ATOM   1250 C  CA  . THR A 1 158 ? 6.946   -8.400  33.197  1.00 51.62  ? 158 THR B CA  1 
ATOM   1251 C  C   . THR A 1 158 ? 6.622   -6.933  33.465  1.00 52.74  ? 158 THR B C   1 
ATOM   1252 O  O   . THR A 1 158 ? 5.464   -6.511  33.451  1.00 54.46  ? 158 THR B O   1 
ATOM   1253 C  CB  . THR A 1 158 ? 7.575   -8.546  31.805  1.00 51.56  ? 158 THR B CB  1 
ATOM   1254 O  OG1 . THR A 1 158 ? 6.816   -7.776  30.858  1.00 61.47  ? 158 THR B OG1 1 
ATOM   1255 C  CG2 . THR A 1 158 ? 7.579   -10.007 31.373  1.00 45.24  ? 158 THR B CG2 1 
ATOM   1256 N  N   . GLY A 1 159 ? 7.670   -6.156  33.709  1.00 52.34  ? 159 GLY B N   1 
ATOM   1257 C  CA  . GLY A 1 159 ? 7.498   -4.719  33.832  1.00 44.37  ? 159 GLY B CA  1 
ATOM   1258 C  C   . GLY A 1 159 ? 6.773   -4.334  35.104  1.00 43.95  ? 159 GLY B C   1 
ATOM   1259 O  O   . GLY A 1 159 ? 7.030   -4.864  36.189  1.00 48.74  ? 159 GLY B O   1 
ATOM   1260 N  N   . LEU A 1 160 ? 5.847   -3.389  34.968  1.00 44.72  ? 160 LEU B N   1 
ATOM   1261 C  CA  . LEU A 1 160 ? 5.170   -2.841  36.135  1.00 41.83  ? 160 LEU B CA  1 
ATOM   1262 C  C   . LEU A 1 160 ? 4.459   -3.928  36.929  1.00 41.87  ? 160 LEU B C   1 
ATOM   1263 O  O   . LEU A 1 160 ? 4.444   -3.896  38.162  1.00 49.35  ? 160 LEU B O   1 
ATOM   1264 C  CB  . LEU A 1 160 ? 4.199   -1.747  35.688  1.00 51.37  ? 160 LEU B CB  1 
ATOM   1265 C  CG  . LEU A 1 160 ? 3.435   -0.929  36.727  1.00 50.16  ? 160 LEU B CG  1 
ATOM   1266 C  CD1 . LEU A 1 160 ? 4.380   -0.216  37.678  1.00 58.89  ? 160 LEU B CD1 1 
ATOM   1267 C  CD2 . LEU A 1 160 ? 2.602   0.070   35.997  1.00 54.15  ? 160 LEU B CD2 1 
ATOM   1268 N  N   . GLY A 1 161 ? 3.881   -4.915  36.250  1.00 44.91  ? 161 GLY B N   1 
ATOM   1269 C  CA  . GLY A 1 161 ? 3.184   -5.960  36.974  1.00 44.21  ? 161 GLY B CA  1 
ATOM   1270 C  C   . GLY A 1 161 ? 4.104   -6.836  37.797  1.00 47.82  ? 161 GLY B C   1 
ATOM   1271 O  O   . GLY A 1 161 ? 3.718   -7.324  38.866  1.00 43.60  ? 161 GLY B O   1 
ATOM   1272 N  N   . GLU A 1 162 ? 5.328   -7.053  37.324  1.00 45.20  ? 162 GLU B N   1 
ATOM   1273 C  CA  . GLU A 1 162 ? 6.266   -7.803  38.143  1.00 48.01  ? 162 GLU B CA  1 
ATOM   1274 C  C   . GLU A 1 162 ? 6.580   -7.044  39.432  1.00 46.57  ? 162 GLU B C   1 
ATOM   1275 O  O   . GLU A 1 162 ? 6.605   -7.635  40.521  1.00 42.07  ? 162 GLU B O   1 
ATOM   1276 C  CB  . GLU A 1 162 ? 7.529   -8.104  37.336  1.00 50.08  ? 162 GLU B CB  1 
ATOM   1277 C  CG  . GLU A 1 162 ? 8.401   -9.224  37.918  1.00 44.46  ? 162 GLU B CG  1 
ATOM   1278 C  CD  . GLU A 1 162 ? 9.629   -9.528  37.057  1.00 49.66  ? 162 GLU B CD  1 
ATOM   1279 O  OE1 . GLU A 1 162 ? 10.192  -8.610  36.405  1.00 49.18  ? 162 GLU B OE1 1 
ATOM   1280 O  OE2 . GLU A 1 162 ? 10.030  -10.709 37.029  1.00 50.89  ? 162 GLU B OE2 1 
ATOM   1281 N  N   . CYS A 1 163 ? 6.789   -5.729  39.321  1.00 46.49  ? 163 CYS B N   1 
ATOM   1282 C  CA  . CYS A 1 163 ? 7.125   -4.904  40.478  1.00 52.79  ? 163 CYS B CA  1 
ATOM   1283 C  C   . CYS A 1 163 ? 6.025   -4.969  41.525  1.00 55.25  ? 163 CYS B C   1 
ATOM   1284 O  O   . CYS A 1 163 ? 6.290   -5.160  42.720  1.00 50.39  ? 163 CYS B O   1 
ATOM   1285 C  CB  . CYS A 1 163 ? 7.328   -3.448  40.048  1.00 51.92  ? 163 CYS B CB  1 
ATOM   1286 S  SG  . CYS A 1 163 ? 8.892   -3.075  39.247  1.00 69.37  ? 163 CYS B SG  1 
ATOM   1287 N  N   . MET A 1 164 ? 4.776   -4.780  41.094  1.00 51.25  ? 164 MET B N   1 
ATOM   1288 C  CA  . MET A 1 164 ? 3.689   -4.756  42.059  1.00 52.60  ? 164 MET B CA  1 
ATOM   1289 C  C   . MET A 1 164 ? 3.506   -6.125  42.689  1.00 52.08  ? 164 MET B C   1 
ATOM   1290 O  O   . MET A 1 164 ? 3.333   -6.237  43.908  1.00 53.94  ? 164 MET B O   1 
ATOM   1291 C  CB  . MET A 1 164 ? 2.404   -4.243  41.398  1.00 60.42  ? 164 MET B CB  1 
ATOM   1292 C  CG  . MET A 1 164 ? 2.378   -2.695  41.230  1.00 68.79  ? 164 MET B CG  1 
ATOM   1293 S  SD  . MET A 1 164 ? 3.735   -1.894  40.309  1.00 102.15 ? 164 MET B SD  1 
ATOM   1294 C  CE  . MET A 1 164 ? 4.715   -1.118  41.610  1.00 69.39  ? 164 MET B CE  1 
ATOM   1295 N  N   . PHE A 1 165 ? 3.602   -7.179  41.882  1.00 51.98  ? 165 PHE B N   1 
ATOM   1296 C  CA  . PHE A 1 165 ? 3.568   -8.529  42.428  1.00 41.95  ? 165 PHE B CA  1 
ATOM   1297 C  C   . PHE A 1 165 ? 4.672   -8.734  43.454  1.00 50.05  ? 165 PHE B C   1 
ATOM   1298 O  O   . PHE A 1 165 ? 4.431   -9.311  44.526  1.00 52.84  ? 165 PHE B O   1 
ATOM   1299 C  CB  . PHE A 1 165 ? 3.694   -9.547  41.301  1.00 40.27  ? 165 PHE B CB  1 
ATOM   1300 C  CG  . PHE A 1 165 ? 3.690   -10.954 41.778  1.00 45.55  ? 165 PHE B CG  1 
ATOM   1301 C  CD1 . PHE A 1 165 ? 2.488   -11.623 41.985  1.00 45.66  ? 165 PHE B CD1 1 
ATOM   1302 C  CD2 . PHE A 1 165 ? 4.881   -11.619 42.028  1.00 39.06  ? 165 PHE B CD2 1 
ATOM   1303 C  CE1 . PHE A 1 165 ? 2.482   -12.931 42.444  1.00 42.17  ? 165 PHE B CE1 1 
ATOM   1304 C  CE2 . PHE A 1 165 ? 4.875   -12.930 42.487  1.00 41.71  ? 165 PHE B CE2 1 
ATOM   1305 C  CZ  . PHE A 1 165 ? 3.677   -13.586 42.695  1.00 36.23  ? 165 PHE B CZ  1 
ATOM   1306 N  N   . ASP A 1 166 ? 5.894   -8.273  43.145  1.00 44.24  ? 166 ASP B N   1 
ATOM   1307 C  CA  . ASP A 1 166 ? 7.006   -8.462  44.073  1.00 46.54  ? 166 ASP B CA  1 
ATOM   1308 C  C   . ASP A 1 166 ? 6.776   -7.730  45.384  1.00 49.35  ? 166 ASP B C   1 
ATOM   1309 O  O   . ASP A 1 166 ? 7.162   -8.238  46.441  1.00 45.90  ? 166 ASP B O   1 
ATOM   1310 C  CB  . ASP A 1 166 ? 8.319   -7.991  43.452  1.00 40.80  ? 166 ASP B CB  1 
ATOM   1311 C  CG  . ASP A 1 166 ? 9.495   -8.148  44.401  1.00 43.57  ? 166 ASP B CG  1 
ATOM   1312 O  OD1 . ASP A 1 166 ? 9.996   -9.285  44.528  1.00 43.09  ? 166 ASP B OD1 1 
ATOM   1313 O  OD2 . ASP A 1 166 ? 9.934   -7.147  45.023  1.00 48.65  ? 166 ASP B OD2 1 
ATOM   1314 N  N   . LYS A 1 167 ? 6.159   -6.539  45.326  1.00 52.34  ? 167 LYS B N   1 
ATOM   1315 C  CA  . LYS A 1 167 ? 5.818   -5.780  46.529  1.00 53.36  ? 167 LYS B CA  1 
ATOM   1316 C  C   . LYS A 1 167 ? 4.782   -6.503  47.378  1.00 54.52  ? 167 LYS B C   1 
ATOM   1317 O  O   . LYS A 1 167 ? 4.912   -6.557  48.604  1.00 60.56  ? 167 LYS B O   1 
ATOM   1318 C  CB  . LYS A 1 167 ? 5.290   -4.395  46.153  1.00 61.92  ? 167 LYS B CB  1 
ATOM   1319 C  CG  . LYS A 1 167 ? 5.154   -3.460  47.356  1.00 65.55  ? 167 LYS B CG  1 
ATOM   1320 C  CD  . LYS A 1 167 ? 4.092   -2.393  47.136  1.00 75.02  ? 167 LYS B CD  1 
ATOM   1321 C  CE  . LYS A 1 167 ? 2.793   -2.746  47.853  1.00 75.44  ? 167 LYS B CE  1 
ATOM   1322 N  NZ  . LYS A 1 167 ? 2.826   -2.330  49.285  1.00 77.52  ? 167 LYS B NZ  1 
ATOM   1323 N  N   . GLU A 1 168 ? 3.738   -7.046  46.746  1.00 53.29  ? 168 GLU B N   1 
ATOM   1324 C  CA  . GLU A 1 168 ? 2.704   -7.770  47.477  1.00 57.87  ? 168 GLU B CA  1 
ATOM   1325 C  C   . GLU A 1 168 ? 3.189   -9.131  47.951  1.00 58.42  ? 168 GLU B C   1 
ATOM   1326 O  O   . GLU A 1 168 ? 2.548   -9.752  48.801  1.00 57.92  ? 168 GLU B O   1 
ATOM   1327 C  CB  . GLU A 1 168 ? 1.457   -7.920  46.603  1.00 51.83  ? 168 GLU B CB  1 
ATOM   1328 C  CG  . GLU A 1 168 ? 0.719   -6.600  46.369  1.00 62.42  ? 168 GLU B CG  1 
ATOM   1329 C  CD  . GLU A 1 168 ? -0.427  -6.731  45.358  1.00 75.18  ? 168 GLU B CD  1 
ATOM   1330 O  OE1 . GLU A 1 168 ? -1.184  -7.737  45.413  1.00 69.69  ? 168 GLU B OE1 1 
ATOM   1331 O  OE2 . GLU A 1 168 ? -0.572  -5.820  44.510  1.00 68.95  ? 168 GLU B OE2 1 
ATOM   1332 N  N   . LEU A 1 169 ? 4.291   -9.618  47.392  1.00 61.66  ? 169 LEU B N   1 
ATOM   1333 C  CA  . LEU A 1 169 ? 4.960   -10.786 47.949  1.00 64.77  ? 169 LEU B CA  1 
ATOM   1334 C  C   . LEU A 1 169 ? 5.622   -10.440 49.269  1.00 71.66  ? 169 LEU B C   1 
ATOM   1335 O  O   . LEU A 1 169 ? 5.536   -11.195 50.250  1.00 69.72  ? 169 LEU B O   1 
ATOM   1336 C  CB  . LEU A 1 169 ? 6.008   -11.273 46.967  1.00 55.42  ? 169 LEU B CB  1 
ATOM   1337 C  CG  . LEU A 1 169 ? 6.353   -12.724 47.034  1.00 53.05  ? 169 LEU B CG  1 
ATOM   1338 C  CD1 . LEU A 1 169 ? 5.056   -13.484 46.977  1.00 51.58  ? 169 LEU B CD1 1 
ATOM   1339 C  CD2 . LEU A 1 169 ? 7.220   -12.985 45.819  1.00 47.24  ? 169 LEU B CD2 1 
ATOM   1340 N  N   . ASN A 1 170 ? 6.305   -9.301  49.292  1.00 67.36  ? 170 ASN B N   1 
ATOM   1341 C  CA  . ASN A 1 170 ? 6.992   -8.813  50.461  1.00 76.35  ? 170 ASN B CA  1 
ATOM   1342 C  C   . ASN A 1 170 ? 5.986   -8.303  51.506  1.00 82.85  ? 170 ASN B C   1 
ATOM   1343 O  O   . ASN A 1 170 ? 4.968   -7.660  51.182  1.00 75.50  ? 170 ASN B O   1 
ATOM   1344 C  CB  . ASN A 1 170 ? 7.984   -7.718  50.054  1.00 65.97  ? 170 ASN B CB  1 
ATOM   1345 C  CG  . ASN A 1 170 ? 9.351   -7.930  50.675  1.00 72.17  ? 170 ASN B CG  1 
ATOM   1346 O  OD1 . ASN A 1 170 ? 9.511   -8.795  51.544  1.00 75.71  ? 170 ASN B OD1 1 
ATOM   1347 N  ND2 . ASN A 1 170 ? 10.339  -7.137  50.255  1.00 57.12  ? 170 ASN B ND2 1 
ATOM   1348 O  OXT . ASN A 1 170 ? 6.175   -8.552  52.704  1.00 84.00  ? 170 ASN B OXT 1 
ATOM   1349 N  N   . ALA B 1 2   ? 29.940  -5.964  32.443  1.00 75.78  ? 2   ALA A N   1 
ATOM   1350 C  CA  . ALA B 1 2   ? 29.942  -6.090  33.900  1.00 81.15  ? 2   ALA A CA  1 
ATOM   1351 C  C   . ALA B 1 2   ? 28.689  -5.455  34.528  1.00 78.08  ? 2   ALA A C   1 
ATOM   1352 O  O   . ALA B 1 2   ? 27.785  -5.009  33.821  1.00 74.87  ? 2   ALA A O   1 
ATOM   1353 C  CB  . ALA B 1 2   ? 31.215  -5.460  34.487  1.00 75.73  ? 2   ALA A CB  1 
ATOM   1354 N  N   . SER B 1 3   ? 28.642  -5.432  35.859  1.00 78.85  ? 3   SER A N   1 
ATOM   1355 C  CA  . SER B 1 3   ? 27.549  -4.792  36.582  1.00 77.43  ? 3   SER A CA  1 
ATOM   1356 C  C   . SER B 1 3   ? 27.580  -3.274  36.410  1.00 75.11  ? 3   SER A C   1 
ATOM   1357 O  O   . SER B 1 3   ? 28.618  -2.668  36.129  1.00 80.40  ? 3   SER A O   1 
ATOM   1358 C  CB  . SER B 1 3   ? 27.621  -5.124  38.077  1.00 65.72  ? 3   SER A CB  1 
ATOM   1359 O  OG  . SER B 1 3   ? 26.809  -6.236  38.398  1.00 66.32  ? 3   SER A OG  1 
ATOM   1360 N  N   . GLN B 1 4   ? 26.417  -2.649  36.608  1.00 72.87  ? 4   GLN A N   1 
ATOM   1361 C  CA  . GLN B 1 4   ? 26.428  -1.212  36.839  1.00 71.95  ? 4   GLN A CA  1 
ATOM   1362 C  C   . GLN B 1 4   ? 27.152  -0.863  38.140  1.00 70.70  ? 4   GLN A C   1 
ATOM   1363 O  O   . GLN B 1 4   ? 27.659  0.256   38.259  1.00 61.93  ? 4   GLN A O   1 
ATOM   1364 C  CB  . GLN B 1 4   ? 24.996  -0.653  36.834  1.00 67.21  ? 4   GLN A CB  1 
ATOM   1365 C  CG  . GLN B 1 4   ? 24.014  -1.394  37.738  1.00 66.54  ? 4   GLN A CG  1 
ATOM   1366 C  CD  . GLN B 1 4   ? 22.556  -0.998  37.500  1.00 58.95  ? 4   GLN A CD  1 
ATOM   1367 O  OE1 . GLN B 1 4   ? 22.147  -0.676  36.385  1.00 69.85  ? 4   GLN A OE1 1 
ATOM   1368 N  NE2 . GLN B 1 4   ? 21.764  -1.064  38.544  1.00 57.00  ? 4   GLN A NE2 1 
ATOM   1369 N  N   . VAL B 1 5   ? 27.250  -1.813  39.086  1.00 73.21  ? 5   VAL A N   1 
ATOM   1370 C  CA  . VAL B 1 5   ? 27.884  -1.576  40.391  1.00 71.56  ? 5   VAL A CA  1 
ATOM   1371 C  C   . VAL B 1 5   ? 29.332  -2.064  40.479  1.00 68.92  ? 5   VAL A C   1 
ATOM   1372 O  O   . VAL B 1 5   ? 30.056  -1.629  41.401  1.00 76.07  ? 5   VAL A O   1 
ATOM   1373 C  CB  . VAL B 1 5   ? 27.058  -2.197  41.553  1.00 68.67  ? 5   VAL A CB  1 
ATOM   1374 C  CG1 . VAL B 1 5   ? 25.609  -1.677  41.565  1.00 58.60  ? 5   VAL A CG1 1 
ATOM   1375 C  CG2 . VAL B 1 5   ? 27.117  -3.762  41.575  1.00 60.78  ? 5   VAL A CG2 1 
ATOM   1376 N  N   . ARG B 1 6   ? 29.792  -2.938  39.583  1.00 67.27  ? 6   ARG A N   1 
ATOM   1377 C  CA  . ARG B 1 6   ? 31.141  -3.491  39.687  1.00 73.94  ? 6   ARG A CA  1 
ATOM   1378 C  C   . ARG B 1 6   ? 32.204  -2.395  39.531  1.00 71.49  ? 6   ARG A C   1 
ATOM   1379 O  O   . ARG B 1 6   ? 32.212  -1.656  38.542  1.00 71.61  ? 6   ARG A O   1 
ATOM   1380 C  CB  . ARG B 1 6   ? 31.356  -4.595  38.640  1.00 70.14  ? 6   ARG A CB  1 
ATOM   1381 C  CG  . ARG B 1 6   ? 32.538  -5.534  38.938  1.00 64.68  ? 6   ARG A CG  1 
ATOM   1382 C  CD  . ARG B 1 6   ? 32.898  -6.448  37.764  1.00 61.14  ? 6   ARG A CD  1 
ATOM   1383 N  NE  . ARG B 1 6   ? 33.795  -7.534  38.179  1.00 64.76  ? 6   ARG A NE  1 
ATOM   1384 C  CZ  . ARG B 1 6   ? 33.463  -8.830  38.216  1.00 64.75  ? 6   ARG A CZ  1 
ATOM   1385 N  NH1 . ARG B 1 6   ? 34.350  -9.747  38.610  1.00 58.93  ? 6   ARG A NH1 1 
ATOM   1386 N  NH2 . ARG B 1 6   ? 32.248  -9.219  37.848  1.00 54.81  ? 6   ARG A NH2 1 
ATOM   1387 N  N   . GLN B 1 7   ? 33.111  -2.310  40.508  1.00 64.96  ? 7   GLN A N   1 
ATOM   1388 C  CA  . GLN B 1 7   ? 34.190  -1.319  40.517  1.00 69.77  ? 7   GLN A CA  1 
ATOM   1389 C  C   . GLN B 1 7   ? 35.411  -1.962  41.170  1.00 72.78  ? 7   GLN A C   1 
ATOM   1390 O  O   . GLN B 1 7   ? 35.370  -2.278  42.366  1.00 67.48  ? 7   GLN A O   1 
ATOM   1391 C  CB  . GLN B 1 7   ? 33.759  -0.060  41.277  1.00 65.44  ? 7   GLN A CB  1 
ATOM   1392 C  CG  . GLN B 1 7   ? 34.520  1.228   40.952  1.00 70.90  ? 7   GLN A CG  1 
ATOM   1393 C  CD  . GLN B 1 7   ? 33.988  2.423   41.753  1.00 68.85  ? 7   GLN A CD  1 
ATOM   1394 O  OE1 . GLN B 1 7   ? 32.937  2.330   42.393  1.00 72.69  ? 7   GLN A OE1 1 
ATOM   1395 N  NE2 . GLN B 1 7   ? 34.712  3.542   41.723  1.00 58.24  ? 7   GLN A NE2 1 
ATOM   1396 N  N   . ASN B 1 8   ? 36.487  -2.172  40.396  1.00 70.02  ? 8   ASN A N   1 
ATOM   1397 C  CA  . ASN B 1 8   ? 37.756  -2.678  40.939  1.00 72.18  ? 8   ASN A CA  1 
ATOM   1398 C  C   . ASN B 1 8   ? 37.561  -4.060  41.593  1.00 68.97  ? 8   ASN A C   1 
ATOM   1399 O  O   . ASN B 1 8   ? 37.889  -4.291  42.764  1.00 64.48  ? 8   ASN A O   1 
ATOM   1400 C  CB  . ASN B 1 8   ? 38.355  -1.639  41.907  1.00 73.71  ? 8   ASN A CB  1 
ATOM   1401 C  CG  . ASN B 1 8   ? 39.620  -2.119  42.621  1.00 78.13  ? 8   ASN A CG  1 
ATOM   1402 O  OD1 . ASN B 1 8   ? 40.663  -2.341  41.991  1.00 72.86  ? 8   ASN A OD1 1 
ATOM   1403 N  ND2 . ASN B 1 8   ? 39.536  -2.245  43.955  1.00 71.32  ? 8   ASN A ND2 1 
ATOM   1404 N  N   . TYR B 1 9   ? 37.004  -4.991  40.812  1.00 74.81  ? 9   TYR A N   1 
ATOM   1405 C  CA  . TYR B 1 9   ? 36.678  -6.345  41.274  1.00 70.03  ? 9   TYR A CA  1 
ATOM   1406 C  C   . TYR B 1 9   ? 37.308  -7.356  40.317  1.00 62.28  ? 9   TYR A C   1 
ATOM   1407 O  O   . TYR B 1 9   ? 36.747  -7.628  39.250  1.00 58.00  ? 9   TYR A O   1 
ATOM   1408 C  CB  . TYR B 1 9   ? 35.165  -6.551  41.362  1.00 64.17  ? 9   TYR A CB  1 
ATOM   1409 C  CG  . TYR B 1 9   ? 34.756  -7.760  42.189  1.00 62.80  ? 9   TYR A CG  1 
ATOM   1410 C  CD1 . TYR B 1 9   ? 35.378  -8.034  43.411  1.00 58.61  ? 9   TYR A CD1 1 
ATOM   1411 C  CD2 . TYR B 1 9   ? 33.752  -8.627  41.749  1.00 56.17  ? 9   TYR A CD2 1 
ATOM   1412 C  CE1 . TYR B 1 9   ? 35.016  -9.122  44.166  1.00 54.09  ? 9   TYR A CE1 1 
ATOM   1413 C  CE2 . TYR B 1 9   ? 33.381  -9.726  42.504  1.00 54.06  ? 9   TYR A CE2 1 
ATOM   1414 C  CZ  . TYR B 1 9   ? 34.019  -9.965  43.709  1.00 53.36  ? 9   TYR A CZ  1 
ATOM   1415 O  OH  . TYR B 1 9   ? 33.666  -11.055 44.462  1.00 50.58  ? 9   TYR A OH  1 
ATOM   1416 N  N   . HIS B 1 10  ? 38.451  -7.924  40.717  1.00 59.73  ? 10  HIS A N   1 
ATOM   1417 C  CA  . HIS B 1 10  ? 39.182  -8.865  39.868  1.00 66.01  ? 10  HIS A CA  1 
ATOM   1418 C  C   . HIS B 1 10  ? 38.456  -10.207 39.753  1.00 67.88  ? 10  HIS A C   1 
ATOM   1419 O  O   . HIS B 1 10  ? 37.901  -10.727 40.730  1.00 63.95  ? 10  HIS A O   1 
ATOM   1420 C  CB  . HIS B 1 10  ? 40.597  -9.089  40.413  1.00 66.94  ? 10  HIS A CB  1 
ATOM   1421 C  CG  . HIS B 1 10  ? 41.580  -9.529  39.376  1.00 64.71  ? 10  HIS A CG  1 
ATOM   1422 N  ND1 . HIS B 1 10  ? 41.533  -10.775 38.788  1.00 64.49  ? 10  HIS A ND1 1 
ATOM   1423 C  CD2 . HIS B 1 10  ? 42.630  -8.885  38.813  1.00 65.03  ? 10  HIS A CD2 1 
ATOM   1424 C  CE1 . HIS B 1 10  ? 42.514  -10.880 37.907  1.00 71.27  ? 10  HIS A CE1 1 
ATOM   1425 N  NE2 . HIS B 1 10  ? 43.192  -9.745  37.900  1.00 66.84  ? 10  HIS A NE2 1 
ATOM   1426 N  N   . GLU B 1 11  ? 38.488  -10.784 38.550  1.00 65.17  ? 11  GLU A N   1 
ATOM   1427 C  CA  . GLU B 1 11  ? 37.711  -11.991 38.297  1.00 62.51  ? 11  GLU A CA  1 
ATOM   1428 C  C   . GLU B 1 11  ? 38.234  -13.196 39.082  1.00 61.94  ? 11  GLU A C   1 
ATOM   1429 O  O   . GLU B 1 11  ? 37.456  -14.105 39.401  1.00 57.08  ? 11  GLU A O   1 
ATOM   1430 C  CB  . GLU B 1 11  ? 37.680  -12.278 36.795  1.00 66.92  ? 11  GLU A CB  1 
ATOM   1431 C  CG  . GLU B 1 11  ? 39.009  -12.767 36.219  1.00 86.54  ? 11  GLU A CG  1 
ATOM   1432 C  CD  . GLU B 1 11  ? 38.834  -13.783 35.088  1.00 91.67  ? 11  GLU A CD  1 
ATOM   1433 O  OE1 . GLU B 1 11  ? 39.793  -13.974 34.308  1.00 86.42  ? 11  GLU A OE1 1 
ATOM   1434 O  OE2 . GLU B 1 11  ? 37.742  -14.385 34.977  1.00 86.40  ? 11  GLU A OE2 1 
ATOM   1435 N  N   . ASP B 1 12  ? 39.534  -13.236 39.411  1.00 67.94  ? 12  ASP A N   1 
ATOM   1436 C  CA  . ASP B 1 12  ? 40.016  -14.338 40.246  1.00 61.40  ? 12  ASP A CA  1 
ATOM   1437 C  C   . ASP B 1 12  ? 39.485  -14.206 41.667  1.00 59.16  ? 12  ASP A C   1 
ATOM   1438 O  O   . ASP B 1 12  ? 39.223  -15.218 42.326  1.00 53.67  ? 12  ASP A O   1 
ATOM   1439 C  CB  . ASP B 1 12  ? 41.544  -14.411 40.243  1.00 56.10  ? 12  ASP A CB  1 
ATOM   1440 C  CG  . ASP B 1 12  ? 42.126  -14.525 38.836  1.00 71.22  ? 12  ASP A CG  1 
ATOM   1441 O  OD1 . ASP B 1 12  ? 41.502  -15.180 37.963  1.00 67.55  ? 12  ASP A OD1 1 
ATOM   1442 O  OD2 . ASP B 1 12  ? 43.214  -13.951 38.604  1.00 72.18  ? 12  ASP A OD2 1 
ATOM   1443 N  N   . CYS B 1 13  ? 39.282  -12.972 42.137  1.00 49.97  ? 13  CYS A N   1 
ATOM   1444 C  CA  . CYS B 1 13  ? 38.571  -12.777 43.394  1.00 55.67  ? 13  CYS A CA  1 
ATOM   1445 C  C   . CYS B 1 13  ? 37.160  -13.352 43.324  1.00 56.23  ? 13  CYS A C   1 
ATOM   1446 O  O   . CYS B 1 13  ? 36.682  -13.967 44.287  1.00 57.01  ? 13  CYS A O   1 
ATOM   1447 C  CB  . CYS B 1 13  ? 38.519  -11.291 43.743  1.00 53.62  ? 13  CYS A CB  1 
ATOM   1448 S  SG  . CYS B 1 13  ? 40.140  -10.581 44.112  1.00 63.16  ? 13  CYS A SG  1 
ATOM   1449 N  N   . GLU B 1 14  ? 36.473  -13.150 42.197  1.00 52.23  ? 14  GLU A N   1 
ATOM   1450 C  CA  . GLU B 1 14  ? 35.107  -13.637 42.063  1.00 46.70  ? 14  GLU A CA  1 
ATOM   1451 C  C   . GLU B 1 14  ? 35.067  -15.156 42.115  1.00 51.18  ? 14  GLU A C   1 
ATOM   1452 O  O   . GLU B 1 14  ? 34.171  -15.746 42.737  1.00 50.80  ? 14  GLU A O   1 
ATOM   1453 C  CB  . GLU B 1 14  ? 34.491  -13.131 40.761  1.00 47.51  ? 14  GLU A CB  1 
ATOM   1454 C  CG  . GLU B 1 14  ? 33.092  -13.656 40.501  1.00 49.07  ? 14  GLU A CG  1 
ATOM   1455 C  CD  . GLU B 1 14  ? 32.501  -13.181 39.171  1.00 53.73  ? 14  GLU A CD  1 
ATOM   1456 O  OE1 . GLU B 1 14  ? 32.960  -12.147 38.631  1.00 56.83  ? 14  GLU A OE1 1 
ATOM   1457 O  OE2 . GLU B 1 14  ? 31.567  -13.845 38.678  1.00 53.70  ? 14  GLU A OE2 1 
ATOM   1458 N  N   . ALA B 1 15  ? 36.042  -15.810 41.488  1.00 50.15  ? 15  ALA A N   1 
ATOM   1459 C  CA  . ALA B 1 15  ? 36.053  -17.263 41.507  1.00 42.20  ? 15  ALA A CA  1 
ATOM   1460 C  C   . ALA B 1 15  ? 36.459  -17.790 42.879  1.00 42.55  ? 15  ALA A C   1 
ATOM   1461 O  O   . ALA B 1 15  ? 35.931  -18.812 43.332  1.00 39.29  ? 15  ALA A O   1 
ATOM   1462 C  CB  . ALA B 1 15  ? 36.972  -17.792 40.406  1.00 38.70  ? 15  ALA A CB  1 
ATOM   1463 N  N   . SER B 1 16  ? 37.372  -17.098 43.573  1.00 40.55  ? 16  SER A N   1 
ATOM   1464 C  CA  . SER B 1 16  ? 37.752  -17.577 44.899  1.00 46.56  ? 16  SER A CA  1 
ATOM   1465 C  C   . SER B 1 16  ? 36.622  -17.387 45.895  1.00 45.42  ? 16  SER A C   1 
ATOM   1466 O  O   . SER B 1 16  ? 36.488  -18.194 46.819  1.00 45.78  ? 16  SER A O   1 
ATOM   1467 C  CB  . SER B 1 16  ? 39.010  -16.882 45.430  1.00 45.94  ? 16  SER A CB  1 
ATOM   1468 O  OG  . SER B 1 16  ? 40.073  -16.911 44.505  1.00 57.39  ? 16  SER A OG  1 
ATOM   1469 N  N   . ILE B 1 17  ? 35.814  -16.329 45.741  1.00 40.02  ? 17  ILE A N   1 
ATOM   1470 C  CA  . ILE B 1 17  ? 34.630  -16.183 46.590  1.00 41.31  ? 17  ILE A CA  1 
ATOM   1471 C  C   . ILE B 1 17  ? 33.653  -17.331 46.349  1.00 41.04  ? 17  ILE A C   1 
ATOM   1472 O  O   . ILE B 1 17  ? 33.050  -17.855 47.295  1.00 39.50  ? 17  ILE A O   1 
ATOM   1473 C  CB  . ILE B 1 17  ? 33.954  -14.824 46.361  1.00 38.93  ? 17  ILE A CB  1 
ATOM   1474 C  CG1 . ILE B 1 17  ? 34.816  -13.687 46.925  1.00 46.98  ? 17  ILE A CG1 1 
ATOM   1475 C  CG2 . ILE B 1 17  ? 32.545  -14.825 46.960  1.00 32.57  ? 17  ILE A CG2 1 
ATOM   1476 C  CD1 . ILE B 1 17  ? 34.530  -13.349 48.401  1.00 50.25  ? 17  ILE A CD1 1 
ATOM   1477 N  N   . ASN B 1 18  ? 33.484  -17.746 45.086  1.00 35.86  ? 18  ASN A N   1 
ATOM   1478 C  CA  . ASN B 1 18  ? 32.629  -18.898 44.805  1.00 37.86  ? 18  ASN A CA  1 
ATOM   1479 C  C   . ASN B 1 18  ? 33.210  -20.165 45.416  1.00 35.26  ? 18  ASN A C   1 
ATOM   1480 O  O   . ASN B 1 18  ? 32.467  -21.011 45.938  1.00 33.79  ? 18  ASN A O   1 
ATOM   1481 C  CB  . ASN B 1 18  ? 32.415  -19.060 43.296  1.00 30.63  ? 18  ASN A CB  1 
ATOM   1482 C  CG  . ASN B 1 18  ? 31.391  -18.039 42.734  1.00 39.85  ? 18  ASN A CG  1 
ATOM   1483 O  OD1 . ASN B 1 18  ? 30.432  -17.661 43.416  1.00 39.18  ? 18  ASN A OD1 1 
ATOM   1484 N  ND2 . ASN B 1 18  ? 31.629  -17.558 41.515  1.00 30.65  ? 18  ASN A ND2 1 
ATOM   1485 N  N   . LYS B 1 19  ? 34.535  -20.302 45.411  1.00 30.23  ? 19  LYS A N   1 
ATOM   1486 C  CA  . LYS B 1 19  ? 35.106  -21.484 46.051  1.00 37.28  ? 19  LYS A CA  1 
ATOM   1487 C  C   . LYS B 1 19  ? 34.816  -21.482 47.556  1.00 36.10  ? 19  LYS A C   1 
ATOM   1488 O  O   . LYS B 1 19  ? 34.481  -22.527 48.123  1.00 35.89  ? 19  LYS A O   1 
ATOM   1489 C  CB  . LYS B 1 19  ? 36.610  -21.596 45.762  1.00 28.29  ? 19  LYS A CB  1 
ATOM   1490 C  CG  . LYS B 1 19  ? 37.232  -22.746 46.506  1.00 35.02  ? 19  LYS A CG  1 
ATOM   1491 C  CD  . LYS B 1 19  ? 38.720  -22.972 46.252  1.00 39.72  ? 19  LYS A CD  1 
ATOM   1492 C  CE  . LYS B 1 19  ? 39.237  -24.000 47.278  1.00 48.84  ? 19  LYS A CE  1 
ATOM   1493 N  NZ  . LYS B 1 19  ? 40.661  -24.406 47.111  1.00 46.96  ? 19  LYS A NZ  1 
ATOM   1494 N  N   . GLN B 1 20  ? 34.847  -20.301 48.199  1.00 34.06  ? 20  GLN A N   1 
ATOM   1495 C  CA  . GLN B 1 20  ? 34.632  -20.215 49.648  1.00 32.55  ? 20  GLN A CA  1 
ATOM   1496 C  C   . GLN B 1 20  ? 33.168  -20.418 50.024  1.00 38.05  ? 20  GLN A C   1 
ATOM   1497 O  O   . GLN B 1 20  ? 32.866  -20.991 51.083  1.00 35.32  ? 20  GLN A O   1 
ATOM   1498 C  CB  . GLN B 1 20  ? 35.119  -18.866 50.180  1.00 37.14  ? 20  GLN A CB  1 
ATOM   1499 C  CG  . GLN B 1 20  ? 35.397  -18.868 51.656  1.00 42.85  ? 20  GLN A CG  1 
ATOM   1500 C  CD  . GLN B 1 20  ? 36.652  -19.667 51.993  1.00 50.69  ? 20  GLN A CD  1 
ATOM   1501 O  OE1 . GLN B 1 20  ? 37.545  -19.806 51.155  1.00 42.49  ? 20  GLN A OE1 1 
ATOM   1502 N  NE2 . GLN B 1 20  ? 36.712  -20.214 53.217  1.00 45.84  ? 20  GLN A NE2 1 
ATOM   1503 N  N   . ILE B 1 21  ? 32.247  -19.912 49.199  1.00 29.36  ? 21  ILE A N   1 
ATOM   1504 C  CA  . ILE B 1 21  ? 30.833  -20.217 49.391  1.00 33.94  ? 21  ILE A CA  1 
ATOM   1505 C  C   . ILE B 1 21  ? 30.629  -21.726 49.484  1.00 35.97  ? 21  ILE A C   1 
ATOM   1506 O  O   . ILE B 1 21  ? 29.927  -22.236 50.376  1.00 30.86  ? 21  ILE A O   1 
ATOM   1507 C  CB  . ILE B 1 21  ? 30.006  -19.609 48.245  1.00 32.37  ? 21  ILE A CB  1 
ATOM   1508 C  CG1 . ILE B 1 21  ? 30.040  -18.069 48.323  1.00 35.55  ? 21  ILE A CG1 1 
ATOM   1509 C  CG2 . ILE B 1 21  ? 28.594  -20.198 48.265  1.00 28.64  ? 21  ILE A CG2 1 
ATOM   1510 C  CD1 . ILE B 1 21  ? 29.418  -17.341 47.101  1.00 34.64  ? 21  ILE A CD1 1 
ATOM   1511 N  N   . ASN B 1 22  ? 31.271  -22.461 48.573  1.00 37.61  ? 22  ASN A N   1 
ATOM   1512 C  CA  . ASN B 1 22  ? 31.170  -23.911 48.552  1.00 36.56  ? 22  ASN A CA  1 
ATOM   1513 C  C   . ASN B 1 22  ? 31.844  -24.526 49.775  1.00 37.46  ? 22  ASN A C   1 
ATOM   1514 O  O   . ASN B 1 22  ? 31.321  -25.484 50.378  1.00 31.74  ? 22  ASN A O   1 
ATOM   1515 C  CB  . ASN B 1 22  ? 31.795  -24.444 47.264  1.00 33.66  ? 22  ASN A CB  1 
ATOM   1516 C  CG  . ASN B 1 22  ? 31.600  -25.915 47.110  1.00 35.51  ? 22  ASN A CG  1 
ATOM   1517 O  OD1 . ASN B 1 22  ? 32.449  -26.726 47.514  1.00 29.53  ? 22  ASN A OD1 1 
ATOM   1518 N  ND2 . ASN B 1 22  ? 30.451  -26.287 46.552  1.00 31.50  ? 22  ASN A ND2 1 
ATOM   1519 N  N   . MET B 1 23  ? 33.007  -23.989 50.147  1.00 30.67  ? 23  MET A N   1 
ATOM   1520 C  CA  . MET B 1 23  ? 33.705  -24.471 51.332  1.00 35.92  ? 23  MET A CA  1 
ATOM   1521 C  C   . MET B 1 23  ? 32.809  -24.395 52.566  1.00 36.96  ? 23  MET A C   1 
ATOM   1522 O  O   . MET B 1 23  ? 32.697  -25.369 53.318  1.00 33.10  ? 23  MET A O   1 
ATOM   1523 C  CB  . MET B 1 23  ? 34.989  -23.668 51.535  1.00 38.82  ? 23  MET A CB  1 
ATOM   1524 C  CG  . MET B 1 23  ? 36.062  -23.960 50.492  1.00 46.59  ? 23  MET A CG  1 
ATOM   1525 S  SD  . MET B 1 23  ? 36.686  -25.661 50.611  1.00 72.54  ? 23  MET A SD  1 
ATOM   1526 C  CE  . MET B 1 23  ? 37.308  -25.675 52.300  1.00 48.41  ? 23  MET A CE  1 
ATOM   1527 N  N   . GLU B 1 24  ? 32.130  -23.256 52.767  1.00 32.79  ? 24  GLU A N   1 
ATOM   1528 C  CA  . GLU B 1 24  ? 31.302  -23.096 53.959  1.00 37.68  ? 24  GLU A CA  1 
ATOM   1529 C  C   . GLU B 1 24  ? 30.052  -23.978 53.906  1.00 37.53  ? 24  GLU A C   1 
ATOM   1530 O  O   . GLU B 1 24  ? 29.623  -24.511 54.936  1.00 36.25  ? 24  GLU A O   1 
ATOM   1531 C  CB  . GLU B 1 24  ? 30.921  -21.627 54.152  1.00 43.98  ? 24  GLU A CB  1 
ATOM   1532 C  CG  . GLU B 1 24  ? 32.092  -20.620 54.104  1.00 47.11  ? 24  GLU A CG  1 
ATOM   1533 C  CD  . GLU B 1 24  ? 32.834  -20.468 55.429  1.00 56.82  ? 24  GLU A CD  1 
ATOM   1534 O  OE1 . GLU B 1 24  ? 33.929  -19.836 55.448  1.00 59.96  ? 24  GLU A OE1 1 
ATOM   1535 O  OE2 . GLU B 1 24  ? 32.322  -20.981 56.446  1.00 55.74  ? 24  GLU A OE2 1 
ATOM   1536 N  N   . LEU B 1 25  ? 29.451  -24.161 52.726  1.00 41.04  ? 25  LEU A N   1 
ATOM   1537 C  CA  . LEU B 1 25  ? 28.278  -25.033 52.659  1.00 35.08  ? 25  LEU A CA  1 
ATOM   1538 C  C   . LEU B 1 25  ? 28.663  -26.468 52.971  1.00 33.26  ? 25  LEU A C   1 
ATOM   1539 O  O   . LEU B 1 25  ? 27.906  -27.190 53.628  1.00 38.74  ? 25  LEU A O   1 
ATOM   1540 C  CB  . LEU B 1 25  ? 27.610  -24.941 51.291  1.00 28.71  ? 25  LEU A CB  1 
ATOM   1541 C  CG  . LEU B 1 25  ? 26.949  -23.612 50.944  1.00 30.12  ? 25  LEU A CG  1 
ATOM   1542 C  CD1 . LEU B 1 25  ? 26.446  -23.650 49.511  1.00 36.89  ? 25  LEU A CD1 1 
ATOM   1543 C  CD2 . LEU B 1 25  ? 25.796  -23.329 51.891  1.00 28.71  ? 25  LEU A CD2 1 
ATOM   1544 N  N   . TYR B 1 26  ? 29.856  -26.879 52.541  1.00 31.69  ? 26  TYR A N   1 
ATOM   1545 C  CA  . TYR B 1 26  ? 30.345  -28.226 52.815  1.00 35.24  ? 26  TYR A CA  1 
ATOM   1546 C  C   . TYR B 1 26  ? 30.597  -28.423 54.313  1.00 33.66  ? 26  TYR A C   1 
ATOM   1547 O  O   . TYR B 1 26  ? 30.087  -29.376 54.921  1.00 30.32  ? 26  TYR A O   1 
ATOM   1548 C  CB  . TYR B 1 26  ? 31.616  -28.495 51.995  1.00 22.97  ? 26  TYR A CB  1 
ATOM   1549 C  CG  . TYR B 1 26  ? 32.361  -29.714 52.453  1.00 26.80  ? 26  TYR A CG  1 
ATOM   1550 C  CD1 . TYR B 1 26  ? 31.826  -30.981 52.269  1.00 36.65  ? 26  TYR A CD1 1 
ATOM   1551 C  CD2 . TYR B 1 26  ? 33.595  -29.609 53.091  1.00 30.64  ? 26  TYR A CD2 1 
ATOM   1552 C  CE1 . TYR B 1 26  ? 32.489  -32.115 52.707  1.00 35.04  ? 26  TYR A CE1 1 
ATOM   1553 C  CE2 . TYR B 1 26  ? 34.270  -30.735 53.523  1.00 31.32  ? 26  TYR A CE2 1 
ATOM   1554 C  CZ  . TYR B 1 26  ? 33.711  -31.991 53.323  1.00 38.16  ? 26  TYR A CZ  1 
ATOM   1555 O  OH  . TYR B 1 26  ? 34.360  -33.137 53.758  1.00 47.25  ? 26  TYR A OH  1 
ATOM   1556 N  N   . ALA B 1 27  ? 31.387  -27.532 54.917  1.00 33.92  ? 27  ALA A N   1 
ATOM   1557 C  CA  . ALA B 1 27  ? 31.539  -27.492 56.373  1.00 36.39  ? 27  ALA A CA  1 
ATOM   1558 C  C   . ALA B 1 27  ? 30.190  -27.590 57.083  1.00 39.59  ? 27  ALA A C   1 
ATOM   1559 O  O   . ALA B 1 27  ? 30.025  -28.372 58.034  1.00 38.38  ? 27  ALA A O   1 
ATOM   1560 C  CB  . ALA B 1 27  ? 32.252  -26.208 56.780  1.00 31.44  ? 27  ALA A CB  1 
ATOM   1561 N  N   . SER B 1 28  ? 29.214  -26.798 56.630  1.00 32.73  ? 28  SER A N   1 
ATOM   1562 C  CA  . SER B 1 28  ? 27.875  -26.862 57.205  1.00 34.67  ? 28  SER A CA  1 
ATOM   1563 C  C   . SER B 1 28  ? 27.313  -28.277 57.095  1.00 34.88  ? 28  SER A C   1 
ATOM   1564 O  O   . SER B 1 28  ? 26.791  -28.836 58.068  1.00 28.62  ? 28  SER A O   1 
ATOM   1565 C  CB  . SER B 1 28  ? 26.978  -25.841 56.497  1.00 33.69  ? 28  SER A CB  1 
ATOM   1566 O  OG  . SER B 1 28  ? 25.621  -25.935 56.905  1.00 33.09  ? 28  SER A OG  1 
ATOM   1567 N  N   . TYR B 1 29  ? 27.461  -28.883 55.913  1.00 32.29  ? 29  TYR A N   1 
ATOM   1568 C  CA  . TYR B 1 29  ? 26.991  -30.241 55.678  1.00 31.10  ? 29  TYR A CA  1 
ATOM   1569 C  C   . TYR B 1 29  ? 27.685  -31.237 56.600  1.00 33.80  ? 29  TYR A C   1 
ATOM   1570 O  O   . TYR B 1 29  ? 27.050  -32.164 57.121  1.00 35.28  ? 29  TYR A O   1 
ATOM   1571 C  CB  . TYR B 1 29  ? 27.236  -30.603 54.215  1.00 30.07  ? 29  TYR A CB  1 
ATOM   1572 C  CG  . TYR B 1 29  ? 26.412  -31.742 53.693  1.00 33.38  ? 29  TYR A CG  1 
ATOM   1573 C  CD1 . TYR B 1 29  ? 25.193  -32.095 54.281  1.00 34.66  ? 29  TYR A CD1 1 
ATOM   1574 C  CD2 . TYR B 1 29  ? 26.856  -32.474 52.609  1.00 35.96  ? 29  TYR A CD2 1 
ATOM   1575 C  CE1 . TYR B 1 29  ? 24.429  -33.149 53.764  1.00 33.26  ? 29  TYR A CE1 1 
ATOM   1576 C  CE2 . TYR B 1 29  ? 26.121  -33.518 52.091  1.00 36.79  ? 29  TYR A CE2 1 
ATOM   1577 C  CZ  . TYR B 1 29  ? 24.922  -33.853 52.670  1.00 36.08  ? 29  TYR A CZ  1 
ATOM   1578 O  OH  . TYR B 1 29  ? 24.236  -34.886 52.131  1.00 32.08  ? 29  TYR A OH  1 
ATOM   1579 N  N   . VAL B 1 30  ? 28.989  -31.065 56.815  1.00 30.50  ? 30  VAL A N   1 
ATOM   1580 C  CA  . VAL B 1 30  ? 29.698  -31.970 57.705  1.00 35.69  ? 30  VAL A CA  1 
ATOM   1581 C  C   . VAL B 1 30  ? 29.174  -31.844 59.131  1.00 37.87  ? 30  VAL A C   1 
ATOM   1582 O  O   . VAL B 1 30  ? 28.937  -32.859 59.801  1.00 35.19  ? 30  VAL A O   1 
ATOM   1583 C  CB  . VAL B 1 30  ? 31.211  -31.728 57.638  1.00 35.01  ? 30  VAL A CB  1 
ATOM   1584 C  CG1 . VAL B 1 30  ? 31.914  -32.555 58.726  1.00 32.90  ? 30  VAL A CG1 1 
ATOM   1585 C  CG2 . VAL B 1 30  ? 31.735  -32.088 56.257  1.00 31.56  ? 30  VAL A CG2 1 
ATOM   1586 N  N   . TYR B 1 31  ? 28.977  -30.610 59.623  1.00 37.92  ? 31  TYR A N   1 
ATOM   1587 C  CA  . TYR B 1 31  ? 28.447  -30.449 60.977  1.00 34.78  ? 31  TYR A CA  1 
ATOM   1588 C  C   . TYR B 1 31  ? 27.036  -31.000 61.073  1.00 35.78  ? 31  TYR A C   1 
ATOM   1589 O  O   . TYR B 1 31  ? 26.665  -31.611 62.082  1.00 31.75  ? 31  TYR A O   1 
ATOM   1590 C  CB  . TYR B 1 31  ? 28.462  -28.990 61.400  1.00 33.88  ? 31  TYR A CB  1 
ATOM   1591 C  CG  . TYR B 1 31  ? 29.823  -28.488 61.798  1.00 40.27  ? 31  TYR A CG  1 
ATOM   1592 C  CD1 . TYR B 1 31  ? 30.590  -29.163 62.759  1.00 39.67  ? 31  TYR A CD1 1 
ATOM   1593 C  CD2 . TYR B 1 31  ? 30.352  -27.336 61.212  1.00 38.67  ? 31  TYR A CD2 1 
ATOM   1594 C  CE1 . TYR B 1 31  ? 31.851  -28.692 63.127  1.00 38.32  ? 31  TYR A CE1 1 
ATOM   1595 C  CE2 . TYR B 1 31  ? 31.600  -26.864 61.563  1.00 42.34  ? 31  TYR A CE2 1 
ATOM   1596 C  CZ  . TYR B 1 31  ? 32.347  -27.542 62.519  1.00 48.62  ? 31  TYR A CZ  1 
ATOM   1597 O  OH  . TYR B 1 31  ? 33.582  -27.052 62.866  1.00 48.03  ? 31  TYR A OH  1 
ATOM   1598 N  N   . LEU B 1 32  ? 26.241  -30.820 60.020  1.00 36.81  ? 32  LEU A N   1 
ATOM   1599 C  CA  . LEU B 1 32  ? 24.922  -31.437 60.000  1.00 35.58  ? 32  LEU A CA  1 
ATOM   1600 C  C   . LEU B 1 32  ? 25.022  -32.947 60.194  1.00 39.13  ? 32  LEU A C   1 
ATOM   1601 O  O   . LEU B 1 32  ? 24.272  -33.531 60.985  1.00 35.39  ? 32  LEU A O   1 
ATOM   1602 C  CB  . LEU B 1 32  ? 24.207  -31.113 58.690  1.00 35.29  ? 32  LEU A CB  1 
ATOM   1603 C  CG  . LEU B 1 32  ? 22.744  -31.595 58.722  1.00 41.65  ? 32  LEU A CG  1 
ATOM   1604 C  CD1 . LEU B 1 32  ? 21.898  -30.732 59.670  1.00 35.79  ? 32  LEU A CD1 1 
ATOM   1605 C  CD2 . LEU B 1 32  ? 22.133  -31.667 57.327  1.00 30.60  ? 32  LEU A CD2 1 
ATOM   1606 N  N   . SER B 1 33  ? 25.952  -33.597 59.476  1.00 37.73  ? 33  SER A N   1 
ATOM   1607 C  CA  . SER B 1 33  ? 26.107  -35.046 59.598  1.00 35.46  ? 33  SER A CA  1 
ATOM   1608 C  C   . SER B 1 33  ? 26.574  -35.435 60.996  1.00 35.60  ? 33  SER A C   1 
ATOM   1609 O  O   . SER B 1 33  ? 26.103  -36.429 61.550  1.00 36.18  ? 33  SER A O   1 
ATOM   1610 C  CB  . SER B 1 33  ? 27.083  -35.570 58.543  1.00 35.00  ? 33  SER A CB  1 
ATOM   1611 O  OG  . SER B 1 33  ? 27.631  -36.836 58.911  1.00 37.28  ? 33  SER A OG  1 
ATOM   1612 N  N   . MET B 1 34  ? 27.505  -34.664 61.573  1.00 30.74  ? 34  MET A N   1 
ATOM   1613 C  CA  . MET B 1 34  ? 27.936  -34.894 62.951  1.00 36.73  ? 34  MET A CA  1 
ATOM   1614 C  C   . MET B 1 34  ? 26.778  -34.743 63.919  1.00 41.89  ? 34  MET A C   1 
ATOM   1615 O  O   . MET B 1 34  ? 26.667  -35.508 64.885  1.00 44.46  ? 34  MET A O   1 
ATOM   1616 C  CB  . MET B 1 34  ? 29.042  -33.913 63.352  1.00 35.59  ? 34  MET A CB  1 
ATOM   1617 C  CG  . MET B 1 34  ? 30.482  -34.373 63.077  1.00 36.26  ? 34  MET A CG  1 
ATOM   1618 S  SD  . MET B 1 34  ? 31.580  -32.947 63.219  1.00 40.50  ? 34  MET A SD  1 
ATOM   1619 C  CE  . MET B 1 34  ? 33.105  -33.620 62.587  1.00 36.89  ? 34  MET A CE  1 
ATOM   1620 N  N   . ALA B 1 35  ? 25.915  -33.748 63.691  1.00 37.36  ? 35  ALA A N   1 
ATOM   1621 C  CA  . ALA B 1 35  ? 24.843  -33.470 64.639  1.00 39.09  ? 35  ALA A CA  1 
ATOM   1622 C  C   . ALA B 1 35  ? 23.908  -34.662 64.761  1.00 41.12  ? 35  ALA A C   1 
ATOM   1623 O  O   . ALA B 1 35  ? 23.631  -35.147 65.865  1.00 37.56  ? 35  ALA A O   1 
ATOM   1624 C  CB  . ALA B 1 35  ? 24.066  -32.227 64.214  1.00 37.33  ? 35  ALA A CB  1 
ATOM   1625 N  N   . TYR B 1 36  ? 23.422  -35.157 63.630  1.00 39.54  ? 36  TYR A N   1 
ATOM   1626 C  CA  . TYR B 1 36  ? 22.489  -36.267 63.663  1.00 38.17  ? 36  TYR A CA  1 
ATOM   1627 C  C   . TYR B 1 36  ? 23.171  -37.593 63.948  1.00 40.44  ? 36  TYR A C   1 
ATOM   1628 O  O   . TYR B 1 36  ? 22.480  -38.562 64.277  1.00 44.26  ? 36  TYR A O   1 
ATOM   1629 C  CB  . TYR B 1 36  ? 21.692  -36.310 62.351  1.00 37.83  ? 36  TYR A CB  1 
ATOM   1630 C  CG  . TYR B 1 36  ? 20.619  -35.258 62.408  1.00 43.05  ? 36  TYR A CG  1 
ATOM   1631 C  CD1 . TYR B 1 36  ? 20.933  -33.919 62.191  1.00 37.59  ? 36  TYR A CD1 1 
ATOM   1632 C  CD2 . TYR B 1 36  ? 19.311  -35.583 62.762  1.00 43.04  ? 36  TYR A CD2 1 
ATOM   1633 C  CE1 . TYR B 1 36  ? 19.983  -32.939 62.285  1.00 41.91  ? 36  TYR A CE1 1 
ATOM   1634 C  CE2 . TYR B 1 36  ? 18.339  -34.598 62.854  1.00 48.90  ? 36  TYR A CE2 1 
ATOM   1635 C  CZ  . TYR B 1 36  ? 18.688  -33.271 62.617  1.00 50.66  ? 36  TYR A CZ  1 
ATOM   1636 O  OH  . TYR B 1 36  ? 17.742  -32.268 62.696  1.00 56.24  ? 36  TYR A OH  1 
ATOM   1637 N  N   . TYR B 1 37  ? 24.499  -37.663 63.847  1.00 36.67  ? 37  TYR A N   1 
ATOM   1638 C  CA  . TYR B 1 37  ? 25.185  -38.873 64.285  1.00 39.04  ? 37  TYR A CA  1 
ATOM   1639 C  C   . TYR B 1 37  ? 25.145  -38.982 65.798  1.00 39.56  ? 37  TYR A C   1 
ATOM   1640 O  O   . TYR B 1 37  ? 24.965  -40.076 66.348  1.00 35.99  ? 37  TYR A O   1 
ATOM   1641 C  CB  . TYR B 1 37  ? 26.629  -38.880 63.793  1.00 32.21  ? 37  TYR A CB  1 
ATOM   1642 C  CG  . TYR B 1 37  ? 27.524  -39.879 64.498  1.00 36.49  ? 37  TYR A CG  1 
ATOM   1643 C  CD1 . TYR B 1 37  ? 27.523  -41.226 64.134  1.00 39.91  ? 37  TYR A CD1 1 
ATOM   1644 C  CD2 . TYR B 1 37  ? 28.392  -39.476 65.524  1.00 39.53  ? 37  TYR A CD2 1 
ATOM   1645 C  CE1 . TYR B 1 37  ? 28.362  -42.154 64.769  1.00 41.77  ? 37  TYR A CE1 1 
ATOM   1646 C  CE2 . TYR B 1 37  ? 29.236  -40.400 66.167  1.00 35.55  ? 37  TYR A CE2 1 
ATOM   1647 C  CZ  . TYR B 1 37  ? 29.211  -41.729 65.780  1.00 37.42  ? 37  TYR A CZ  1 
ATOM   1648 O  OH  . TYR B 1 37  ? 30.026  -42.643 66.400  1.00 45.63  ? 37  TYR A OH  1 
ATOM   1649 N  N   . PHE B 1 38  ? 25.320  -37.856 66.483  1.00 37.20  ? 38  PHE A N   1 
ATOM   1650 C  CA  . PHE B 1 38  ? 25.297  -37.835 67.935  1.00 38.94  ? 38  PHE A CA  1 
ATOM   1651 C  C   . PHE B 1 38  ? 23.886  -37.948 68.496  1.00 40.15  ? 38  PHE A C   1 
ATOM   1652 O  O   . PHE B 1 38  ? 23.723  -38.087 69.711  1.00 39.15  ? 38  PHE A O   1 
ATOM   1653 C  CB  . PHE B 1 38  ? 26.018  -36.579 68.432  1.00 37.51  ? 38  PHE A CB  1 
ATOM   1654 C  CG  . PHE B 1 38  ? 27.512  -36.714 68.369  1.00 37.37  ? 38  PHE A CG  1 
ATOM   1655 C  CD1 . PHE B 1 38  ? 28.187  -37.490 69.303  1.00 38.48  ? 38  PHE A CD1 1 
ATOM   1656 C  CD2 . PHE B 1 38  ? 28.239  -36.130 67.346  1.00 33.40  ? 38  PHE A CD2 1 
ATOM   1657 C  CE1 . PHE B 1 38  ? 29.583  -37.658 69.237  1.00 38.68  ? 38  PHE A CE1 1 
ATOM   1658 C  CE2 . PHE B 1 38  ? 29.634  -36.296 67.277  1.00 38.12  ? 38  PHE A CE2 1 
ATOM   1659 C  CZ  . PHE B 1 38  ? 30.299  -37.063 68.231  1.00 36.14  ? 38  PHE A CZ  1 
ATOM   1660 N  N   . GLU B 1 39  ? 22.874  -37.962 67.636  1.00 37.72  ? 39  GLU A N   1 
ATOM   1661 C  CA  . GLU B 1 39  ? 21.506  -38.219 68.049  1.00 40.16  ? 39  GLU A CA  1 
ATOM   1662 C  C   . GLU B 1 39  ? 21.089  -39.669 67.831  1.00 36.45  ? 39  GLU A C   1 
ATOM   1663 O  O   . GLU B 1 39  ? 19.951  -40.020 68.152  1.00 35.32  ? 39  GLU A O   1 
ATOM   1664 C  CB  . GLU B 1 39  ? 20.555  -37.282 67.296  1.00 41.05  ? 39  GLU A CB  1 
ATOM   1665 C  CG  . GLU B 1 39  ? 20.641  -35.846 67.741  1.00 34.84  ? 39  GLU A CG  1 
ATOM   1666 C  CD  . GLU B 1 39  ? 19.424  -35.039 67.317  1.00 45.09  ? 39  GLU A CD  1 
ATOM   1667 O  OE1 . GLU B 1 39  ? 18.601  -35.570 66.542  1.00 44.79  ? 39  GLU A OE1 1 
ATOM   1668 O  OE2 . GLU B 1 39  ? 19.284  -33.878 67.769  1.00 55.42  ? 39  GLU A OE2 1 
ATOM   1669 N  N   . ARG B 1 40  ? 21.974  -40.503 67.275  1.00 37.32  ? 40  ARG A N   1 
ATOM   1670 C  CA  . ARG B 1 40  ? 21.699  -41.927 67.106  1.00 42.39  ? 40  ARG A CA  1 
ATOM   1671 C  C   . ARG B 1 40  ? 21.390  -42.570 68.452  1.00 40.81  ? 40  ARG A C   1 
ATOM   1672 O  O   . ARG B 1 40  ? 22.023  -42.259 69.460  1.00 41.78  ? 40  ARG A O   1 
ATOM   1673 C  CB  . ARG B 1 40  ? 22.903  -42.631 66.477  1.00 36.98  ? 40  ARG A CB  1 
ATOM   1674 C  CG  . ARG B 1 40  ? 22.846  -42.774 64.998  1.00 37.35  ? 40  ARG A CG  1 
ATOM   1675 C  CD  . ARG B 1 40  ? 24.188  -43.199 64.407  1.00 46.90  ? 40  ARG A CD  1 
ATOM   1676 N  NE  . ARG B 1 40  ? 24.687  -44.466 64.940  1.00 55.79  ? 40  ARG A NE  1 
ATOM   1677 C  CZ  . ARG B 1 40  ? 25.656  -45.191 64.379  1.00 60.94  ? 40  ARG A CZ  1 
ATOM   1678 N  NH1 . ARG B 1 40  ? 26.220  -44.785 63.247  1.00 59.27  ? 40  ARG A NH1 1 
ATOM   1679 N  NH2 . ARG B 1 40  ? 26.062  -46.327 64.947  1.00 59.57  ? 40  ARG A NH2 1 
ATOM   1680 N  N   . ASP B 1 41  ? 20.435  -43.500 68.456  1.00 41.49  ? 41  ASP A N   1 
ATOM   1681 C  CA  . ASP B 1 41  ? 20.048  -44.174 69.693  1.00 48.33  ? 41  ASP A CA  1 
ATOM   1682 C  C   . ASP B 1 41  ? 21.194  -44.955 70.340  1.00 51.98  ? 41  ASP A C   1 
ATOM   1683 O  O   . ASP B 1 41  ? 21.123  -45.248 71.540  1.00 53.64  ? 41  ASP A O   1 
ATOM   1684 C  CB  . ASP B 1 41  ? 18.889  -45.125 69.428  1.00 50.99  ? 41  ASP A CB  1 
ATOM   1685 C  CG  . ASP B 1 41  ? 19.338  -46.372 68.715  1.00 56.05  ? 41  ASP A CG  1 
ATOM   1686 O  OD1 . ASP B 1 41  ? 19.489  -46.328 67.468  1.00 50.88  ? 41  ASP A OD1 1 
ATOM   1687 O  OD2 . ASP B 1 41  ? 19.561  -47.389 69.419  1.00 65.29  ? 41  ASP A OD2 1 
ATOM   1688 N  N   . ASP B 1 42  ? 22.229  -45.334 69.583  1.00 44.74  ? 42  ASP A N   1 
ATOM   1689 C  CA  . ASP B 1 42  ? 23.397  -45.977 70.170  1.00 43.76  ? 42  ASP A CA  1 
ATOM   1690 C  C   . ASP B 1 42  ? 24.542  -44.987 70.412  1.00 41.32  ? 42  ASP A C   1 
ATOM   1691 O  O   . ASP B 1 42  ? 25.684  -45.406 70.630  1.00 39.65  ? 42  ASP A O   1 
ATOM   1692 C  CB  . ASP B 1 42  ? 23.862  -47.166 69.310  1.00 39.73  ? 42  ASP A CB  1 
ATOM   1693 C  CG  . ASP B 1 42  ? 24.196  -46.782 67.861  1.00 47.75  ? 42  ASP A CG  1 
ATOM   1694 O  OD1 . ASP B 1 42  ? 24.040  -45.611 67.485  1.00 44.98  ? 42  ASP A OD1 1 
ATOM   1695 O  OD2 . ASP B 1 42  ? 24.625  -47.664 67.091  1.00 52.59  ? 42  ASP A OD2 1 
ATOM   1696 N  N   . VAL B 1 43  ? 24.260  -43.685 70.384  1.00 41.16  ? 43  VAL A N   1 
ATOM   1697 C  CA  . VAL B 1 43  ? 25.284  -42.677 70.646  1.00 40.46  ? 43  VAL A CA  1 
ATOM   1698 C  C   . VAL B 1 43  ? 24.800  -41.711 71.714  1.00 38.76  ? 43  VAL A C   1 
ATOM   1699 O  O   . VAL B 1 43  ? 25.453  -41.561 72.749  1.00 39.65  ? 43  VAL A O   1 
ATOM   1700 C  CB  . VAL B 1 43  ? 25.684  -41.923 69.367  1.00 41.93  ? 43  VAL A CB  1 
ATOM   1701 C  CG1 . VAL B 1 43  ? 26.712  -40.865 69.709  1.00 37.80  ? 43  VAL A CG1 1 
ATOM   1702 C  CG2 . VAL B 1 43  ? 26.244  -42.885 68.323  1.00 36.89  ? 43  VAL A CG2 1 
ATOM   1703 N  N   . CYS B 1 44  ? 23.680  -41.024 71.451  1.00 43.96  ? 44  CYS A N   1 
ATOM   1704 C  CA  . CYS B 1 44  ? 22.901  -40.286 72.459  1.00 43.50  ? 44  CYS A CA  1 
ATOM   1705 C  C   . CYS B 1 44  ? 23.750  -39.295 73.244  1.00 37.20  ? 44  CYS A C   1 
ATOM   1706 O  O   . CYS B 1 44  ? 23.856  -39.377 74.460  1.00 40.46  ? 44  CYS A O   1 
ATOM   1707 C  CB  . CYS B 1 44  ? 22.209  -41.232 73.449  1.00 43.66  ? 44  CYS A CB  1 
ATOM   1708 S  SG  . CYS B 1 44  ? 21.023  -42.393 72.742  1.00 74.18  ? 44  CYS A SG  1 
ATOM   1709 N  N   . LEU B 1 45  ? 24.345  -38.338 72.538  1.00 41.41  ? 45  LEU A N   1 
ATOM   1710 C  CA  . LEU B 1 45  ? 25.137  -37.287 73.174  1.00 41.96  ? 45  LEU A CA  1 
ATOM   1711 C  C   . LEU B 1 45  ? 24.535  -35.937 72.796  1.00 42.22  ? 45  LEU A C   1 
ATOM   1712 O  O   . LEU B 1 45  ? 25.043  -35.249 71.901  1.00 44.28  ? 45  LEU A O   1 
ATOM   1713 C  CB  . LEU B 1 45  ? 26.604  -37.401 72.777  1.00 38.25  ? 45  LEU A CB  1 
ATOM   1714 C  CG  . LEU B 1 45  ? 27.359  -38.469 73.558  1.00 37.89  ? 45  LEU A CG  1 
ATOM   1715 C  CD1 . LEU B 1 45  ? 28.667  -38.882 72.868  1.00 38.02  ? 45  LEU A CD1 1 
ATOM   1716 C  CD2 . LEU B 1 45  ? 27.631  -37.968 74.953  1.00 42.16  ? 45  LEU A CD2 1 
ATOM   1717 N  N   . PRO B 1 46  ? 23.450  -35.525 73.467  1.00 49.25  ? 46  PRO A N   1 
ATOM   1718 C  CA  . PRO B 1 46  ? 22.732  -34.304 73.040  1.00 41.80  ? 46  PRO A CA  1 
ATOM   1719 C  C   . PRO B 1 46  ? 23.561  -33.036 73.120  1.00 39.57  ? 46  PRO A C   1 
ATOM   1720 O  O   . PRO B 1 46  ? 23.311  -32.096 72.354  1.00 40.28  ? 46  PRO A O   1 
ATOM   1721 C  CB  . PRO B 1 46  ? 21.531  -34.251 74.007  1.00 39.84  ? 46  PRO A CB  1 
ATOM   1722 C  CG  . PRO B 1 46  ? 21.987  -35.059 75.225  1.00 31.36  ? 46  PRO A CG  1 
ATOM   1723 C  CD  . PRO B 1 46  ? 22.793  -36.179 74.616  1.00 42.02  ? 46  PRO A CD  1 
ATOM   1724 N  N   . GLY B 1 47  ? 24.527  -32.970 74.039  1.00 42.24  ? 47  GLY A N   1 
ATOM   1725 C  CA  . GLY B 1 47  ? 25.430  -31.827 74.069  1.00 42.46  ? 47  GLY A CA  1 
ATOM   1726 C  C   . GLY B 1 47  ? 26.266  -31.704 72.802  1.00 45.67  ? 47  GLY A C   1 
ATOM   1727 O  O   . GLY B 1 47  ? 26.327  -30.634 72.186  1.00 44.62  ? 47  GLY A O   1 
ATOM   1728 N  N   . PHE B 1 48  ? 26.929  -32.798 72.394  1.00 37.10  ? 48  PHE A N   1 
ATOM   1729 C  CA  . PHE B 1 48  ? 27.634  -32.770 71.113  1.00 40.00  ? 48  PHE A CA  1 
ATOM   1730 C  C   . PHE B 1 48  ? 26.667  -32.451 69.977  1.00 39.61  ? 48  PHE A C   1 
ATOM   1731 O  O   . PHE B 1 48  ? 26.955  -31.593 69.132  1.00 34.00  ? 48  PHE A O   1 
ATOM   1732 C  CB  . PHE B 1 48  ? 28.348  -34.101 70.849  1.00 36.73  ? 48  PHE A CB  1 
ATOM   1733 C  CG  . PHE B 1 48  ? 29.611  -34.312 71.676  1.00 44.38  ? 48  PHE A CG  1 
ATOM   1734 C  CD1 . PHE B 1 48  ? 29.568  -34.998 72.883  1.00 39.04  ? 48  PHE A CD1 1 
ATOM   1735 C  CD2 . PHE B 1 48  ? 30.842  -33.852 71.227  1.00 42.01  ? 48  PHE A CD2 1 
ATOM   1736 C  CE1 . PHE B 1 48  ? 30.712  -35.201 73.625  1.00 39.54  ? 48  PHE A CE1 1 
ATOM   1737 C  CE2 . PHE B 1 48  ? 31.993  -34.056 71.972  1.00 40.87  ? 48  PHE A CE2 1 
ATOM   1738 C  CZ  . PHE B 1 48  ? 31.929  -34.732 73.164  1.00 42.69  ? 48  PHE A CZ  1 
ATOM   1739 N  N   . ALA B 1 49  ? 25.493  -33.098 69.973  1.00 35.17  ? 49  ALA A N   1 
ATOM   1740 C  CA  . ALA B 1 49  ? 24.535  -32.922 68.886  1.00 35.78  ? 49  ALA A CA  1 
ATOM   1741 C  C   . ALA B 1 49  ? 24.131  -31.460 68.736  1.00 39.74  ? 49  ALA A C   1 
ATOM   1742 O  O   . ALA B 1 49  ? 24.136  -30.918 67.624  1.00 39.57  ? 49  ALA A O   1 
ATOM   1743 C  CB  . ALA B 1 49  ? 23.301  -33.802 69.116  1.00 31.16  ? 49  ALA A CB  1 
ATOM   1744 N  N   . LYS B 1 50  ? 23.779  -30.805 69.853  1.00 41.39  ? 50  LYS A N   1 
ATOM   1745 C  CA  . LYS B 1 50  ? 23.427  -29.387 69.827  1.00 37.82  ? 50  LYS A CA  1 
ATOM   1746 C  C   . LYS B 1 50  ? 24.597  -28.539 69.335  1.00 42.10  ? 50  LYS A C   1 
ATOM   1747 O  O   . LYS B 1 50  ? 24.430  -27.671 68.468  1.00 38.13  ? 50  LYS A O   1 
ATOM   1748 C  CB  . LYS B 1 50  ? 22.979  -28.943 71.223  1.00 47.49  ? 50  LYS A CB  1 
ATOM   1749 C  CG  . LYS B 1 50  ? 22.566  -27.482 71.366  1.00 43.22  ? 50  LYS A CG  1 
ATOM   1750 C  CD  . LYS B 1 50  ? 21.861  -27.256 72.702  1.00 51.11  ? 50  LYS A CD  1 
ATOM   1751 C  CE  . LYS B 1 50  ? 21.473  -25.807 72.926  1.00 58.25  ? 50  LYS A CE  1 
ATOM   1752 N  NZ  . LYS B 1 50  ? 22.240  -25.208 74.066  1.00 71.36  ? 50  LYS A NZ  1 
ATOM   1753 N  N   . PHE B 1 51  ? 25.799  -28.786 69.870  1.00 35.17  ? 51  PHE A N   1 
ATOM   1754 C  CA  . PHE B 1 51  ? 26.970  -28.041 69.418  1.00 35.00  ? 51  PHE A CA  1 
ATOM   1755 C  C   . PHE B 1 51  ? 27.136  -28.116 67.901  1.00 42.47  ? 51  PHE A C   1 
ATOM   1756 O  O   . PHE B 1 51  ? 27.294  -27.088 67.229  1.00 42.65  ? 51  PHE A O   1 
ATOM   1757 C  CB  . PHE B 1 51  ? 28.230  -28.564 70.102  1.00 36.35  ? 51  PHE A CB  1 
ATOM   1758 C  CG  . PHE B 1 51  ? 29.480  -27.805 69.725  1.00 34.78  ? 51  PHE A CG  1 
ATOM   1759 C  CD1 . PHE B 1 51  ? 29.730  -26.552 70.260  1.00 30.72  ? 51  PHE A CD1 1 
ATOM   1760 C  CD2 . PHE B 1 51  ? 30.397  -28.347 68.831  1.00 33.92  ? 51  PHE A CD2 1 
ATOM   1761 C  CE1 . PHE B 1 51  ? 30.868  -25.854 69.908  1.00 39.00  ? 51  PHE A CE1 1 
ATOM   1762 C  CE2 . PHE B 1 51  ? 31.556  -27.659 68.470  1.00 28.81  ? 51  PHE A CE2 1 
ATOM   1763 C  CZ  . PHE B 1 51  ? 31.789  -26.410 68.998  1.00 38.24  ? 51  PHE A CZ  1 
ATOM   1764 N  N   . PHE B 1 52  ? 27.104  -29.333 67.344  1.00 38.47  ? 52  PHE A N   1 
ATOM   1765 C  CA  . PHE B 1 52  ? 27.323  -29.495 65.914  1.00 37.92  ? 52  PHE A CA  1 
ATOM   1766 C  C   . PHE B 1 52  ? 26.151  -28.986 65.088  1.00 38.49  ? 52  PHE A C   1 
ATOM   1767 O  O   . PHE B 1 52  ? 26.349  -28.606 63.937  1.00 35.53  ? 52  PHE A O   1 
ATOM   1768 C  CB  . PHE B 1 52  ? 27.632  -30.962 65.587  1.00 30.71  ? 52  PHE A CB  1 
ATOM   1769 C  CG  . PHE B 1 52  ? 28.963  -31.419 66.122  1.00 34.08  ? 52  PHE A CG  1 
ATOM   1770 C  CD1 . PHE B 1 52  ? 30.099  -30.632 65.964  1.00 34.54  ? 52  PHE A CD1 1 
ATOM   1771 C  CD2 . PHE B 1 52  ? 29.079  -32.622 66.812  1.00 37.90  ? 52  PHE A CD2 1 
ATOM   1772 C  CE1 . PHE B 1 52  ? 31.329  -31.032 66.484  1.00 34.62  ? 52  PHE A CE1 1 
ATOM   1773 C  CE2 . PHE B 1 52  ? 30.318  -33.037 67.334  1.00 34.71  ? 52  PHE A CE2 1 
ATOM   1774 C  CZ  . PHE B 1 52  ? 31.438  -32.241 67.168  1.00 32.39  ? 52  PHE A CZ  1 
ATOM   1775 N  N   . LYS B 1 53  ? 24.944  -28.924 65.649  1.00 42.87  ? 53  LYS A N   1 
ATOM   1776 C  CA  . LYS B 1 53  ? 23.829  -28.409 64.859  1.00 44.07  ? 53  LYS A CA  1 
ATOM   1777 C  C   . LYS B 1 53  ? 23.905  -26.890 64.733  1.00 42.75  ? 53  LYS A C   1 
ATOM   1778 O  O   . LYS B 1 53  ? 23.568  -26.323 63.684  1.00 43.25  ? 53  LYS A O   1 
ATOM   1779 C  CB  . LYS B 1 53  ? 22.502  -28.850 65.473  1.00 40.61  ? 53  LYS A CB  1 
ATOM   1780 C  CG  . LYS B 1 53  ? 21.351  -28.860 64.485  1.00 52.55  ? 53  LYS A CG  1 
ATOM   1781 C  CD  . LYS B 1 53  ? 20.594  -30.193 64.513  1.00 60.28  ? 53  LYS A CD  1 
ATOM   1782 C  CE  . LYS B 1 53  ? 20.350  -30.699 65.945  1.00 61.49  ? 53  LYS A CE  1 
ATOM   1783 N  NZ  . LYS B 1 53  ? 19.245  -31.706 65.993  1.00 57.09  ? 53  LYS A NZ  1 
ATOM   1784 N  N   . GLU B 1 54  ? 24.374  -26.220 65.784  1.00 44.76  ? 54  GLU A N   1 
ATOM   1785 C  CA  . GLU B 1 54  ? 24.567  -24.775 65.741  1.00 41.20  ? 54  GLU A CA  1 
ATOM   1786 C  C   . GLU B 1 54  ? 25.752  -24.404 64.857  1.00 45.19  ? 54  GLU A C   1 
ATOM   1787 O  O   . GLU B 1 54  ? 25.690  -23.421 64.104  1.00 40.84  ? 54  GLU A O   1 
ATOM   1788 C  CB  . GLU B 1 54  ? 24.785  -24.243 67.155  1.00 38.71  ? 54  GLU A CB  1 
ATOM   1789 C  CG  . GLU B 1 54  ? 23.606  -24.381 68.103  1.00 44.46  ? 54  GLU A CG  1 
ATOM   1790 C  CD  . GLU B 1 54  ? 23.949  -23.846 69.502  1.00 59.49  ? 54  GLU A CD  1 
ATOM   1791 O  OE1 . GLU B 1 54  ? 25.153  -23.836 69.861  1.00 53.08  ? 54  GLU A OE1 1 
ATOM   1792 O  OE2 . GLU B 1 54  ? 23.020  -23.435 70.234  1.00 64.17  ? 54  GLU A OE2 1 
ATOM   1793 N  N   . SER B 1 55  ? 26.849  -25.167 64.965  1.00 37.53  ? 55  SER A N   1 
ATOM   1794 C  CA  . SER B 1 55  ? 27.960  -25.031 64.034  1.00 38.27  ? 55  SER A CA  1 
ATOM   1795 C  C   . SER B 1 55  ? 27.470  -25.147 62.593  1.00 42.60  ? 55  SER A C   1 
ATOM   1796 O  O   . SER B 1 55  ? 27.852  -24.351 61.727  1.00 39.09  ? 55  SER A O   1 
ATOM   1797 C  CB  . SER B 1 55  ? 29.001  -26.108 64.331  1.00 38.14  ? 55  SER A CB  1 
ATOM   1798 O  OG  . SER B 1 55  ? 29.761  -25.791 65.479  1.00 42.08  ? 55  SER A OG  1 
ATOM   1799 N  N   . SER B 1 56  ? 26.593  -26.122 62.327  1.00 39.34  ? 56  SER A N   1 
ATOM   1800 C  CA  . SER B 1 56  ? 26.069  -26.306 60.980  1.00 38.57  ? 56  SER A CA  1 
ATOM   1801 C  C   . SER B 1 56  ? 25.309  -25.085 60.500  1.00 40.15  ? 56  SER A C   1 
ATOM   1802 O  O   . SER B 1 56  ? 25.446  -24.688 59.336  1.00 39.44  ? 56  SER A O   1 
ATOM   1803 C  CB  . SER B 1 56  ? 25.164  -27.524 60.911  1.00 33.80  ? 56  SER A CB  1 
ATOM   1804 O  OG  . SER B 1 56  ? 24.769  -27.711 59.560  1.00 34.65  ? 56  SER A OG  1 
ATOM   1805 N  N   . ASP B 1 57  ? 24.487  -24.496 61.377  1.00 42.19  ? 57  ASP A N   1 
ATOM   1806 C  CA  . ASP B 1 57  ? 23.772  -23.265 61.048  1.00 40.89  ? 57  ASP A CA  1 
ATOM   1807 C  C   . ASP B 1 57  ? 24.742  -22.101 60.863  1.00 41.75  ? 57  ASP A C   1 
ATOM   1808 O  O   . ASP B 1 57  ? 24.595  -21.305 59.929  1.00 42.03  ? 57  ASP A O   1 
ATOM   1809 C  CB  . ASP B 1 57  ? 22.755  -22.933 62.145  1.00 34.77  ? 57  ASP A CB  1 
ATOM   1810 C  CG  . ASP B 1 57  ? 21.645  -23.962 62.253  1.00 41.31  ? 57  ASP A CG  1 
ATOM   1811 O  OD1 . ASP B 1 57  ? 21.456  -24.773 61.317  1.00 45.40  ? 57  ASP A OD1 1 
ATOM   1812 O  OD2 . ASP B 1 57  ? 20.962  -23.973 63.297  1.00 45.67  ? 57  ASP A OD2 1 
ATOM   1813 N  N   . GLU B 1 58  ? 25.728  -21.983 61.754  1.00 37.86  ? 58  GLU A N   1 
ATOM   1814 C  CA  . GLU B 1 58  ? 26.750  -20.947 61.647  1.00 42.29  ? 58  GLU A CA  1 
ATOM   1815 C  C   . GLU B 1 58  ? 27.394  -20.951 60.261  1.00 45.55  ? 58  GLU A C   1 
ATOM   1816 O  O   . GLU B 1 58  ? 27.393  -19.935 59.561  1.00 43.75  ? 58  GLU A O   1 
ATOM   1817 C  CB  . GLU B 1 58  ? 27.815  -21.174 62.725  1.00 50.58  ? 58  GLU A CB  1 
ATOM   1818 C  CG  . GLU B 1 58  ? 28.023  -20.071 63.749  1.00 62.26  ? 58  GLU A CG  1 
ATOM   1819 C  CD  . GLU B 1 58  ? 28.915  -20.540 64.909  1.00 78.77  ? 58  GLU A CD  1 
ATOM   1820 O  OE1 . GLU B 1 58  ? 29.961  -19.891 65.161  1.00 85.09  ? 58  GLU A OE1 1 
ATOM   1821 O  OE2 . GLU B 1 58  ? 28.572  -21.565 65.560  1.00 71.10  ? 58  GLU A OE2 1 
ATOM   1822 N  N   . GLU B 1 59  ? 27.945  -22.102 59.850  1.00 41.84  ? 59  GLU A N   1 
ATOM   1823 C  CA  . GLU B 1 59  ? 28.622  -22.212 58.558  1.00 43.80  ? 59  GLU A CA  1 
ATOM   1824 C  C   . GLU B 1 59  ? 27.688  -21.861 57.404  1.00 42.17  ? 59  GLU A C   1 
ATOM   1825 O  O   . GLU B 1 59  ? 28.098  -21.219 56.424  1.00 36.58  ? 59  GLU A O   1 
ATOM   1826 C  CB  . GLU B 1 59  ? 29.164  -23.629 58.371  1.00 40.65  ? 59  GLU A CB  1 
ATOM   1827 C  CG  . GLU B 1 59  ? 30.141  -24.035 59.421  1.00 42.71  ? 59  GLU A CG  1 
ATOM   1828 C  CD  . GLU B 1 59  ? 31.304  -23.101 59.454  1.00 53.61  ? 59  GLU A CD  1 
ATOM   1829 O  OE1 . GLU B 1 59  ? 31.769  -22.756 60.561  1.00 63.60  ? 59  GLU A OE1 1 
ATOM   1830 O  OE2 . GLU B 1 59  ? 31.748  -22.709 58.356  1.00 58.35  ? 59  GLU A OE2 1 
ATOM   1831 N  N   . ARG B 1 60  ? 26.433  -22.292 57.491  1.00 37.59  ? 60  ARG A N   1 
ATOM   1832 C  CA  . ARG B 1 60  ? 25.495  -21.943 56.439  1.00 39.27  ? 60  ARG A CA  1 
ATOM   1833 C  C   . ARG B 1 60  ? 25.310  -20.430 56.368  1.00 42.26  ? 60  ARG A C   1 
ATOM   1834 O  O   . ARG B 1 60  ? 25.199  -19.867 55.273  1.00 41.97  ? 60  ARG A O   1 
ATOM   1835 C  CB  . ARG B 1 60  ? 24.172  -22.663 56.665  1.00 33.97  ? 60  ARG A CB  1 
ATOM   1836 C  CG  . ARG B 1 60  ? 23.325  -22.747 55.428  1.00 35.50  ? 60  ARG A CG  1 
ATOM   1837 C  CD  . ARG B 1 60  ? 21.920  -23.216 55.766  1.00 49.84  ? 60  ARG A CD  1 
ATOM   1838 N  NE  . ARG B 1 60  ? 21.039  -23.112 54.605  1.00 51.61  ? 60  ARG A NE  1 
ATOM   1839 C  CZ  . ARG B 1 60  ? 19.746  -22.803 54.679  1.00 55.90  ? 60  ARG A CZ  1 
ATOM   1840 N  NH1 . ARG B 1 60  ? 18.998  -22.712 53.569  1.00 44.34  ? 60  ARG A NH1 1 
ATOM   1841 N  NH2 . ARG B 1 60  ? 19.203  -22.577 55.873  1.00 56.18  ? 60  ARG A NH2 1 
ATOM   1842 N  N   . GLU B 1 61  ? 25.321  -19.747 57.521  1.00 40.55  ? 61  GLU A N   1 
ATOM   1843 C  CA  . GLU B 1 61  ? 25.238  -18.289 57.508  1.00 41.92  ? 61  GLU A CA  1 
ATOM   1844 C  C   . GLU B 1 61  ? 26.506  -17.661 56.937  1.00 40.73  ? 61  GLU A C   1 
ATOM   1845 O  O   . GLU B 1 61  ? 26.421  -16.681 56.189  1.00 43.03  ? 61  GLU A O   1 
ATOM   1846 C  CB  . GLU B 1 61  ? 24.935  -17.751 58.911  1.00 41.55  ? 61  GLU A CB  1 
ATOM   1847 C  CG  . GLU B 1 61  ? 23.466  -17.979 59.362  1.00 52.40  ? 61  GLU A CG  1 
ATOM   1848 C  CD  . GLU B 1 61  ? 22.405  -17.390 58.394  1.00 68.55  ? 61  GLU A CD  1 
ATOM   1849 O  OE1 . GLU B 1 61  ? 21.287  -17.974 58.299  1.00 66.30  ? 61  GLU A OE1 1 
ATOM   1850 O  OE2 . GLU B 1 61  ? 22.672  -16.342 57.743  1.00 63.43  ? 61  GLU A OE2 1 
ATOM   1851 N  N   . HIS B 1 62  ? 27.692  -18.210 57.257  1.00 40.52  ? 62  HIS A N   1 
ATOM   1852 C  CA  . HIS B 1 62  ? 28.931  -17.714 56.643  1.00 44.81  ? 62  HIS A CA  1 
ATOM   1853 C  C   . HIS B 1 62  ? 28.873  -17.784 55.121  1.00 44.27  ? 62  HIS A C   1 
ATOM   1854 O  O   . HIS B 1 62  ? 29.324  -16.859 54.440  1.00 44.42  ? 62  HIS A O   1 
ATOM   1855 C  CB  . HIS B 1 62  ? 30.145  -18.503 57.116  1.00 48.57  ? 62  HIS A CB  1 
ATOM   1856 C  CG  . HIS B 1 62  ? 30.609  -18.150 58.491  1.00 64.55  ? 62  HIS A CG  1 
ATOM   1857 N  ND1 . HIS B 1 62  ? 31.564  -18.886 59.162  1.00 64.78  ? 62  HIS A ND1 1 
ATOM   1858 C  CD2 . HIS B 1 62  ? 30.252  -17.145 59.324  1.00 69.82  ? 62  HIS A CD2 1 
ATOM   1859 C  CE1 . HIS B 1 62  ? 31.772  -18.351 60.351  1.00 60.76  ? 62  HIS A CE1 1 
ATOM   1860 N  NE2 . HIS B 1 62  ? 30.989  -17.295 60.475  1.00 69.76  ? 62  HIS A NE2 1 
ATOM   1861 N  N   . ALA B 1 63  ? 28.347  -18.887 54.571  1.00 38.04  ? 63  ALA A N   1 
ATOM   1862 C  CA  . ALA B 1 63  ? 28.253  -19.015 53.120  1.00 41.24  ? 63  ALA A CA  1 
ATOM   1863 C  C   . ALA B 1 63  ? 27.328  -17.948 52.544  1.00 37.94  ? 63  ALA A C   1 
ATOM   1864 O  O   . ALA B 1 63  ? 27.634  -17.330 51.517  1.00 35.18  ? 63  ALA A O   1 
ATOM   1865 C  CB  . ALA B 1 63  ? 27.783  -20.432 52.736  1.00 34.83  ? 63  ALA A CB  1 
ATOM   1866 N  N   . GLN B 1 64  ? 26.204  -17.692 53.209  1.00 38.69  ? 64  GLN A N   1 
ATOM   1867 C  CA  . GLN B 1 64  ? 25.312  -16.641 52.739  1.00 40.53  ? 64  GLN A CA  1 
ATOM   1868 C  C   . GLN B 1 64  ? 25.981  -15.275 52.790  1.00 43.27  ? 64  GLN A C   1 
ATOM   1869 O  O   . GLN B 1 64  ? 25.675  -14.395 51.978  1.00 43.00  ? 64  GLN A O   1 
ATOM   1870 C  CB  . GLN B 1 64  ? 24.036  -16.674 53.552  1.00 38.66  ? 64  GLN A CB  1 
ATOM   1871 C  CG  . GLN B 1 64  ? 23.263  -17.912 53.206  1.00 38.08  ? 64  GLN A CG  1 
ATOM   1872 C  CD  . GLN B 1 64  ? 21.903  -17.930 53.820  1.00 43.58  ? 64  GLN A CD  1 
ATOM   1873 O  OE1 . GLN B 1 64  ? 20.987  -17.229 53.372  1.00 56.62  ? 64  GLN A OE1 1 
ATOM   1874 N  NE2 . GLN B 1 64  ? 21.747  -18.731 54.847  1.00 41.83  ? 64  GLN A NE2 1 
ATOM   1875 N  N   . THR B 1 65  ? 26.952  -15.104 53.678  1.00 42.71  ? 65  THR A N   1 
ATOM   1876 C  CA  . THR B 1 65  ? 27.628  -13.825 53.757  1.00 40.16  ? 65  THR A CA  1 
ATOM   1877 C  C   . THR B 1 65  ? 28.542  -13.612 52.555  1.00 40.09  ? 65  THR A C   1 
ATOM   1878 O  O   . THR B 1 65  ? 28.566  -12.521 51.967  1.00 43.25  ? 65  THR A O   1 
ATOM   1879 C  CB  . THR B 1 65  ? 28.350  -13.751 55.091  1.00 44.00  ? 65  THR A CB  1 
ATOM   1880 O  OG1 . THR B 1 65  ? 27.361  -13.517 56.101  1.00 47.21  ? 65  THR A OG1 1 
ATOM   1881 C  CG2 . THR B 1 65  ? 29.383  -12.642 55.119  1.00 39.27  ? 65  THR A CG2 1 
ATOM   1882 N  N   . PHE B 1 66  ? 29.256  -14.646 52.127  1.00 40.85  ? 66  PHE A N   1 
ATOM   1883 C  CA  . PHE B 1 66  ? 30.016  -14.497 50.894  1.00 36.54  ? 66  PHE A CA  1 
ATOM   1884 C  C   . PHE B 1 66  ? 29.105  -14.368 49.678  1.00 38.44  ? 66  PHE A C   1 
ATOM   1885 O  O   . PHE B 1 66  ? 29.455  -13.667 48.726  1.00 39.46  ? 66  PHE A O   1 
ATOM   1886 C  CB  . PHE B 1 66  ? 30.961  -15.658 50.727  1.00 33.75  ? 66  PHE A CB  1 
ATOM   1887 C  CG  . PHE B 1 66  ? 32.055  -15.673 51.722  1.00 42.86  ? 66  PHE A CG  1 
ATOM   1888 C  CD1 . PHE B 1 66  ? 33.059  -14.716 51.676  1.00 43.96  ? 66  PHE A CD1 1 
ATOM   1889 C  CD2 . PHE B 1 66  ? 32.104  -16.652 52.699  1.00 42.06  ? 66  PHE A CD2 1 
ATOM   1890 C  CE1 . PHE B 1 66  ? 34.091  -14.733 52.580  1.00 44.93  ? 66  PHE A CE1 1 
ATOM   1891 C  CE2 . PHE B 1 66  ? 33.141  -16.671 53.614  1.00 49.19  ? 66  PHE A CE2 1 
ATOM   1892 C  CZ  . PHE B 1 66  ? 34.140  -15.713 53.547  1.00 44.61  ? 66  PHE A CZ  1 
ATOM   1893 N  N   . MET B 1 67  ? 27.927  -14.999 49.695  1.00 38.09  ? 67  MET A N   1 
ATOM   1894 C  CA  . MET B 1 67  ? 26.996  -14.837 48.582  1.00 39.38  ? 67  MET A CA  1 
ATOM   1895 C  C   . MET B 1 67  ? 26.549  -13.377 48.435  1.00 41.94  ? 67  MET A C   1 
ATOM   1896 O  O   . MET B 1 67  ? 26.650  -12.795 47.349  1.00 42.65  ? 67  MET A O   1 
ATOM   1897 C  CB  . MET B 1 67  ? 25.804  -15.770 48.765  1.00 35.25  ? 67  MET A CB  1 
ATOM   1898 C  CG  . MET B 1 67  ? 26.190  -17.242 48.674  1.00 44.62  ? 67  MET A CG  1 
ATOM   1899 S  SD  . MET B 1 67  ? 24.863  -18.435 49.002  1.00 41.51  ? 67  MET A SD  1 
ATOM   1900 C  CE  . MET B 1 67  ? 23.791  -18.174 47.600  1.00 34.33  ? 67  MET A CE  1 
ATOM   1901 N  N   . LYS B 1 68  ? 26.060  -12.764 49.519  1.00 39.24  ? 68  LYS A N   1 
ATOM   1902 C  CA  . LYS B 1 68  ? 25.717  -11.344 49.462  1.00 41.66  ? 68  LYS A CA  1 
ATOM   1903 C  C   . LYS B 1 68  ? 26.923  -10.505 49.080  1.00 41.80  ? 68  LYS A C   1 
ATOM   1904 O  O   . LYS B 1 68  ? 26.796  -9.548  48.306  1.00 43.01  ? 68  LYS A O   1 
ATOM   1905 C  CB  . LYS B 1 68  ? 25.125  -10.850 50.793  1.00 41.65  ? 68  LYS A CB  1 
ATOM   1906 C  CG  . LYS B 1 68  ? 24.111  -11.788 51.448  1.00 57.21  ? 68  LYS A CG  1 
ATOM   1907 C  CD  . LYS B 1 68  ? 23.536  -11.233 52.757  1.00 63.39  ? 68  LYS A CD  1 
ATOM   1908 C  CE  . LYS B 1 68  ? 23.578  -12.283 53.884  1.00 61.62  ? 68  LYS A CE  1 
ATOM   1909 N  NZ  . LYS B 1 68  ? 23.951  -11.731 55.232  1.00 61.66  ? 68  LYS A NZ  1 
ATOM   1910 N  N   . TYR B 1 69  ? 28.111  -10.861 49.578  1.00 36.63  ? 69  TYR A N   1 
ATOM   1911 C  CA  . TYR B 1 69  ? 29.282  -10.097 49.174  1.00 39.15  ? 69  TYR A CA  1 
ATOM   1912 C  C   . TYR B 1 69  ? 29.567  -10.274 47.687  1.00 45.35  ? 69  TYR A C   1 
ATOM   1913 O  O   . TYR B 1 69  ? 29.965  -9.320  47.006  1.00 43.24  ? 69  TYR A O   1 
ATOM   1914 C  CB  . TYR B 1 69  ? 30.506  -10.479 49.997  1.00 42.56  ? 69  TYR A CB  1 
ATOM   1915 C  CG  . TYR B 1 69  ? 31.625  -9.520  49.709  1.00 46.57  ? 69  TYR A CG  1 
ATOM   1916 C  CD1 . TYR B 1 69  ? 31.580  -8.207  50.189  1.00 51.57  ? 69  TYR A CD1 1 
ATOM   1917 C  CD2 . TYR B 1 69  ? 32.682  -9.890  48.891  1.00 39.76  ? 69  TYR A CD2 1 
ATOM   1918 C  CE1 . TYR B 1 69  ? 32.591  -7.304  49.895  1.00 51.43  ? 69  TYR A CE1 1 
ATOM   1919 C  CE2 . TYR B 1 69  ? 33.692  -9.004  48.586  1.00 49.86  ? 69  TYR A CE2 1 
ATOM   1920 C  CZ  . TYR B 1 69  ? 33.649  -7.710  49.095  1.00 53.89  ? 69  TYR A CZ  1 
ATOM   1921 O  OH  . TYR B 1 69  ? 34.663  -6.834  48.794  1.00 51.45  ? 69  TYR A OH  1 
ATOM   1922 N  N   . GLN B 1 70  ? 29.368  -11.485 47.163  1.00 41.89  ? 70  GLN A N   1 
ATOM   1923 C  CA  . GLN B 1 70  ? 29.507  -11.678 45.729  1.00 45.26  ? 70  GLN A CA  1 
ATOM   1924 C  C   . GLN B 1 70  ? 28.545  -10.772 44.982  1.00 44.17  ? 70  GLN A C   1 
ATOM   1925 O  O   . GLN B 1 70  ? 28.936  -10.062 44.049  1.00 39.02  ? 70  GLN A O   1 
ATOM   1926 C  CB  . GLN B 1 70  ? 29.261  -13.137 45.359  1.00 45.60  ? 70  GLN A CB  1 
ATOM   1927 C  CG  . GLN B 1 70  ? 29.452  -13.422 43.878  1.00 39.03  ? 70  GLN A CG  1 
ATOM   1928 C  CD  . GLN B 1 70  ? 30.919  -13.672 43.536  1.00 49.76  ? 70  GLN A CD  1 
ATOM   1929 O  OE1 . GLN B 1 70  ? 31.740  -12.753 43.544  1.00 46.85  ? 70  GLN A OE1 1 
ATOM   1930 N  NE2 . GLN B 1 70  ? 31.254  -14.926 43.262  1.00 43.24  ? 70  GLN A NE2 1 
ATOM   1931 N  N   . ASN B 1 71  ? 27.280  -10.763 45.398  1.00 40.41  ? 71  ASN A N   1 
ATOM   1932 C  CA  . ASN B 1 71  ? 26.298  -9.938  44.709  1.00 43.90  ? 71  ASN A CA  1 
ATOM   1933 C  C   . ASN B 1 71  ? 26.626  -8.455  44.832  1.00 52.47  ? 71  ASN A C   1 
ATOM   1934 O  O   . ASN B 1 71  ? 26.477  -7.694  43.864  1.00 53.25  ? 71  ASN A O   1 
ATOM   1935 C  CB  . ASN B 1 71  ? 24.913  -10.217 45.261  1.00 37.16  ? 71  ASN A CB  1 
ATOM   1936 C  CG  . ASN B 1 71  ? 24.221  -11.333 44.518  1.00 40.16  ? 71  ASN A CG  1 
ATOM   1937 O  OD1 . ASN B 1 71  ? 24.621  -11.700 43.409  1.00 43.63  ? 71  ASN A OD1 1 
ATOM   1938 N  ND2 . ASN B 1 71  ? 23.187  -11.892 45.126  1.00 38.96  ? 71  ASN A ND2 1 
ATOM   1939 N  N   . CYS B 1 72  ? 27.082  -8.035  46.016  1.00 48.99  ? 72  CYS A N   1 
ATOM   1940 C  CA  . CYS B 1 72  ? 27.330  -6.623  46.280  1.00 53.71  ? 72  CYS A CA  1 
ATOM   1941 C  C   . CYS B 1 72  ? 28.443  -6.070  45.389  1.00 47.24  ? 72  CYS A C   1 
ATOM   1942 O  O   . CYS B 1 72  ? 28.298  -4.989  44.808  1.00 48.03  ? 72  CYS A O   1 
ATOM   1943 C  CB  . CYS B 1 72  ? 27.640  -6.438  47.771  1.00 53.51  ? 72  CYS A CB  1 
ATOM   1944 S  SG  . CYS B 1 72  ? 28.613  -4.975  48.197  1.00 86.09  ? 72  CYS A SG  1 
ATOM   1945 N  N   . ARG B 1 73  ? 29.546  -6.795  45.249  1.00 43.54  ? 73  ARG A N   1 
ATOM   1946 C  CA  . ARG B 1 73  ? 30.564  -6.374  44.289  1.00 45.36  ? 73  ARG A CA  1 
ATOM   1947 C  C   . ARG B 1 73  ? 30.133  -6.551  42.843  1.00 45.54  ? 73  ARG A C   1 
ATOM   1948 O  O   . ARG B 1 73  ? 30.906  -6.200  41.953  1.00 52.65  ? 73  ARG A O   1 
ATOM   1949 C  CB  . ARG B 1 73  ? 31.869  -7.136  44.512  1.00 46.31  ? 73  ARG A CB  1 
ATOM   1950 C  CG  . ARG B 1 73  ? 32.428  -6.999  45.908  1.00 48.66  ? 73  ARG A CG  1 
ATOM   1951 C  CD  . ARG B 1 73  ? 32.633  -5.537  46.297  1.00 53.45  ? 73  ARG A CD  1 
ATOM   1952 N  NE  . ARG B 1 73  ? 33.630  -4.874  45.455  1.00 55.26  ? 73  ARG A NE  1 
ATOM   1953 C  CZ  . ARG B 1 73  ? 34.946  -5.044  45.576  1.00 58.80  ? 73  ARG A CZ  1 
ATOM   1954 N  NH1 . ARG B 1 73  ? 35.445  -5.864  46.502  1.00 54.00  ? 73  ARG A NH1 1 
ATOM   1955 N  NH2 . ARG B 1 73  ? 35.770  -4.397  44.761  1.00 63.02  ? 73  ARG A NH2 1 
ATOM   1956 N  N   . GLY B 1 74  ? 28.936  -7.074  42.582  1.00 48.15  ? 74  GLY A N   1 
ATOM   1957 C  CA  . GLY B 1 74  ? 28.502  -7.292  41.218  1.00 49.77  ? 74  GLY A CA  1 
ATOM   1958 C  C   . GLY B 1 74  ? 29.108  -8.492  40.522  1.00 51.44  ? 74  GLY A C   1 
ATOM   1959 O  O   . GLY B 1 74  ? 29.030  -8.590  39.293  1.00 51.17  ? 74  GLY A O   1 
ATOM   1960 N  N   . GLY B 1 75  ? 29.741  -9.400  41.261  1.00 50.89  ? 75  GLY A N   1 
ATOM   1961 C  CA  . GLY B 1 75  ? 30.118  -10.685 40.712  1.00 49.12  ? 75  GLY A CA  1 
ATOM   1962 C  C   . GLY B 1 75  ? 28.903  -11.588 40.616  1.00 51.11  ? 75  GLY A C   1 
ATOM   1963 O  O   . GLY B 1 75  ? 27.775  -11.211 40.951  1.00 42.24  ? 75  GLY A O   1 
ATOM   1964 N  N   . ARG B 1 76  ? 29.138  -12.812 40.153  1.00 43.38  ? 76  ARG A N   1 
ATOM   1965 C  CA  . ARG B 1 76  ? 28.042  -13.736 39.889  1.00 47.88  ? 76  ARG A CA  1 
ATOM   1966 C  C   . ARG B 1 76  ? 28.259  -15.010 40.685  1.00 40.89  ? 76  ARG A C   1 
ATOM   1967 O  O   . ARG B 1 76  ? 29.308  -15.657 40.568  1.00 41.61  ? 76  ARG A O   1 
ATOM   1968 C  CB  . ARG B 1 76  ? 27.902  -14.018 38.391  1.00 49.05  ? 76  ARG A CB  1 
ATOM   1969 C  CG  . ARG B 1 76  ? 27.504  -12.737 37.609  1.00 68.41  ? 76  ARG A CG  1 
ATOM   1970 C  CD  . ARG B 1 76  ? 26.227  -12.055 38.197  1.00 69.34  ? 76  ARG A CD  1 
ATOM   1971 N  NE  . ARG B 1 76  ? 26.075  -10.640 37.839  1.00 78.16  ? 76  ARG A NE  1 
ATOM   1972 C  CZ  . ARG B 1 76  ? 25.907  -9.625  38.699  1.00 75.64  ? 76  ARG A CZ  1 
ATOM   1973 N  NH1 . ARG B 1 76  ? 25.793  -9.836  40.008  1.00 65.74  ? 76  ARG A NH1 1 
ATOM   1974 N  NH2 . ARG B 1 76  ? 25.750  -8.389  38.216  1.00 74.64  ? 76  ARG A NH2 1 
ATOM   1975 N  N   . ILE B 1 77  ? 27.290  -15.330 41.542  1.00 41.89  ? 77  ILE A N   1 
ATOM   1976 C  CA  . ILE B 1 77  ? 27.369  -16.566 42.302  1.00 41.93  ? 77  ILE A CA  1 
ATOM   1977 C  C   . ILE B 1 77  ? 27.263  -17.731 41.338  1.00 36.45  ? 77  ILE A C   1 
ATOM   1978 O  O   . ILE B 1 77  ? 26.378  -17.761 40.475  1.00 35.30  ? 77  ILE A O   1 
ATOM   1979 C  CB  . ILE B 1 77  ? 26.264  -16.636 43.359  1.00 38.86  ? 77  ILE A CB  1 
ATOM   1980 C  CG1 . ILE B 1 77  ? 26.455  -15.532 44.395  1.00 38.41  ? 77  ILE A CG1 1 
ATOM   1981 C  CG2 . ILE B 1 77  ? 26.250  -18.033 43.995  1.00 36.81  ? 77  ILE A CG2 1 
ATOM   1982 C  CD1 . ILE B 1 77  ? 25.163  -15.000 44.958  1.00 38.16  ? 77  ILE A CD1 1 
ATOM   1983 N  N   . VAL B 1 78  ? 28.182  -18.679 41.456  1.00 36.50  ? 78  VAL A N   1 
ATOM   1984 C  CA  . VAL B 1 78  ? 28.100  -19.939 40.733  1.00 35.07  ? 78  VAL A CA  1 
ATOM   1985 C  C   . VAL B 1 78  ? 28.230  -21.032 41.778  1.00 33.91  ? 78  VAL A C   1 
ATOM   1986 O  O   . VAL B 1 78  ? 29.311  -21.233 42.347  1.00 32.80  ? 78  VAL A O   1 
ATOM   1987 C  CB  . VAL B 1 78  ? 29.172  -20.078 39.644  1.00 37.21  ? 78  VAL A CB  1 
ATOM   1988 C  CG1 . VAL B 1 78  ? 29.102  -21.478 39.039  1.00 31.14  ? 78  VAL A CG1 1 
ATOM   1989 C  CG2 . VAL B 1 78  ? 28.980  -18.999 38.568  1.00 30.25  ? 78  VAL A CG2 1 
ATOM   1990 N  N   . LEU B 1 79  ? 27.123  -21.705 42.060  1.00 30.84  ? 79  LEU A N   1 
ATOM   1991 C  CA  . LEU B 1 79  ? 27.093  -22.751 43.069  1.00 34.64  ? 79  LEU A CA  1 
ATOM   1992 C  C   . LEU B 1 79  ? 27.625  -24.056 42.479  1.00 32.44  ? 79  LEU A C   1 
ATOM   1993 O  O   . LEU B 1 79  ? 27.409  -24.360 41.304  1.00 37.60  ? 79  LEU A O   1 
ATOM   1994 C  CB  . LEU B 1 79  ? 25.664  -22.929 43.602  1.00 30.36  ? 79  LEU A CB  1 
ATOM   1995 C  CG  . LEU B 1 79  ? 25.067  -21.722 44.342  1.00 30.98  ? 79  LEU A CG  1 
ATOM   1996 C  CD1 . LEU B 1 79  ? 23.591  -21.948 44.590  1.00 30.59  ? 79  LEU A CD1 1 
ATOM   1997 C  CD2 . LEU B 1 79  ? 25.808  -21.448 45.666  1.00 26.05  ? 79  LEU A CD2 1 
ATOM   1998 N  N   . GLN B 1 80  ? 28.341  -24.811 43.297  1.00 30.46  ? 80  GLN A N   1 
ATOM   1999 C  CA  . GLN B 1 80  ? 28.932  -26.076 42.911  1.00 30.32  ? 80  GLN A CA  1 
ATOM   2000 C  C   . GLN B 1 80  ? 28.377  -27.154 43.816  1.00 34.78  ? 80  GLN A C   1 
ATOM   2001 O  O   . GLN B 1 80  ? 27.894  -26.868 44.921  1.00 34.49  ? 80  GLN A O   1 
ATOM   2002 C  CB  . GLN B 1 80  ? 30.462  -26.048 43.036  1.00 33.06  ? 80  GLN A CB  1 
ATOM   2003 C  CG  . GLN B 1 80  ? 31.144  -25.036 42.135  1.00 31.47  ? 80  GLN A CG  1 
ATOM   2004 C  CD  . GLN B 1 80  ? 31.172  -25.493 40.679  1.00 32.88  ? 80  GLN A CD  1 
ATOM   2005 O  OE1 . GLN B 1 80  ? 30.940  -26.677 40.359  1.00 33.53  ? 80  GLN A OE1 1 
ATOM   2006 N  NE2 . GLN B 1 80  ? 31.458  -24.563 39.793  1.00 30.07  ? 80  GLN A NE2 1 
ATOM   2007 N  N   . GLN B 1 81  ? 28.472  -28.396 43.341  1.00 34.14  ? 81  GLN A N   1 
ATOM   2008 C  CA  . GLN B 1 81  ? 28.020  -29.536 44.125  1.00 33.29  ? 81  GLN A CA  1 
ATOM   2009 C  C   . GLN B 1 81  ? 28.644  -29.487 45.512  1.00 32.46  ? 81  GLN A C   1 
ATOM   2010 O  O   . GLN B 1 81  ? 29.829  -29.178 45.660  1.00 32.36  ? 81  GLN A O   1 
ATOM   2011 C  CB  . GLN B 1 81  ? 28.404  -30.837 43.427  1.00 29.18  ? 81  GLN A CB  1 
ATOM   2012 C  CG  . GLN B 1 81  ? 28.160  -32.083 44.258  1.00 27.78  ? 81  GLN A CG  1 
ATOM   2013 C  CD  . GLN B 1 81  ? 28.026  -33.314 43.376  1.00 37.28  ? 81  GLN A CD  1 
ATOM   2014 O  OE1 . GLN B 1 81  ? 26.977  -33.526 42.744  1.00 37.05  ? 81  GLN A OE1 1 
ATOM   2015 N  NE2 . GLN B 1 81  ? 29.081  -34.133 43.323  1.00 31.75  ? 81  GLN A NE2 1 
ATOM   2016 N  N   . ILE B 1 82  ? 27.838  -29.757 46.534  1.00 32.06  ? 82  ILE A N   1 
ATOM   2017 C  CA  . ILE B 1 82  ? 28.336  -29.844 47.906  1.00 34.54  ? 82  ILE A CA  1 
ATOM   2018 C  C   . ILE B 1 82  ? 28.715  -31.301 48.136  1.00 28.43  ? 82  ILE A C   1 
ATOM   2019 O  O   . ILE B 1 82  ? 27.858  -32.185 48.063  1.00 33.12  ? 82  ILE A O   1 
ATOM   2020 C  CB  . ILE B 1 82  ? 27.287  -29.367 48.921  1.00 37.41  ? 82  ILE A CB  1 
ATOM   2021 C  CG1 . ILE B 1 82  ? 26.839  -27.933 48.624  1.00 28.64  ? 82  ILE A CG1 1 
ATOM   2022 C  CG2 . ILE B 1 82  ? 27.801  -29.494 50.358  1.00 33.04  ? 82  ILE A CG2 1 
ATOM   2023 C  CD1 . ILE B 1 82  ? 25.518  -27.634 49.244  1.00 31.97  ? 82  ILE A CD1 1 
ATOM   2024 N  N   . ALA B 1 83  ? 30.000  -31.560 48.375  1.00 31.85  ? 83  ALA A N   1 
ATOM   2025 C  CA  . ALA B 1 83  ? 30.470  -32.939 48.508  1.00 31.63  ? 83  ALA A CA  1 
ATOM   2026 C  C   . ALA B 1 83  ? 29.871  -33.605 49.748  1.00 40.48  ? 83  ALA A C   1 
ATOM   2027 O  O   . ALA B 1 83  ? 29.536  -32.944 50.741  1.00 42.32  ? 83  ALA A O   1 
ATOM   2028 C  CB  . ALA B 1 83  ? 31.998  -32.984 48.598  1.00 23.61  ? 83  ALA A CB  1 
ATOM   2029 N  N   . ALA B 1 84  ? 29.741  -34.929 49.682  1.00 34.14  ? 84  ALA A N   1 
ATOM   2030 C  CA  . ALA B 1 84  ? 29.365  -35.712 50.851  1.00 40.67  ? 84  ALA A CA  1 
ATOM   2031 C  C   . ALA B 1 84  ? 30.449  -35.610 51.932  1.00 44.04  ? 84  ALA A C   1 
ATOM   2032 O  O   . ALA B 1 84  ? 31.629  -35.422 51.626  1.00 45.05  ? 84  ALA A O   1 
ATOM   2033 C  CB  . ALA B 1 84  ? 29.147  -37.173 50.461  1.00 37.33  ? 84  ALA A CB  1 
ATOM   2034 N  N   . PRO B 1 85  ? 30.072  -35.699 53.205  1.00 45.58  ? 85  PRO A N   1 
ATOM   2035 C  CA  . PRO B 1 85  ? 31.066  -35.622 54.280  1.00 44.33  ? 85  PRO A CA  1 
ATOM   2036 C  C   . PRO B 1 85  ? 32.080  -36.755 54.215  1.00 43.73  ? 85  PRO A C   1 
ATOM   2037 O  O   . PRO B 1 85  ? 31.856  -37.788 53.583  1.00 38.95  ? 85  PRO A O   1 
ATOM   2038 C  CB  . PRO B 1 85  ? 30.220  -35.716 55.554  1.00 46.24  ? 85  PRO A CB  1 
ATOM   2039 C  CG  . PRO B 1 85  ? 28.901  -35.197 55.144  1.00 41.47  ? 85  PRO A CG  1 
ATOM   2040 C  CD  . PRO B 1 85  ? 28.695  -35.633 53.721  1.00 40.17  ? 85  PRO A CD  1 
ATOM   2041 N  N   . SER B 1 86  ? 33.219  -36.519 54.890  1.00 50.06  ? 86  SER A N   1 
ATOM   2042 C  CA  . SER B 1 86  ? 34.319  -37.483 54.985  1.00 54.76  ? 86  SER A CA  1 
ATOM   2043 C  C   . SER B 1 86  ? 33.814  -38.875 55.346  1.00 56.75  ? 86  SER A C   1 
ATOM   2044 O  O   . SER B 1 86  ? 34.253  -39.881 54.771  1.00 54.07  ? 86  SER A O   1 
ATOM   2045 C  CB  . SER B 1 86  ? 35.315  -37.030 56.065  1.00 57.00  ? 86  SER A CB  1 
ATOM   2046 O  OG  . SER B 1 86  ? 35.471  -35.616 56.111  1.00 62.07  ? 86  SER A OG  1 
ATOM   2047 N  N   . MET B 1 87  ? 32.911  -38.951 56.328  1.00 53.04  ? 87  MET A N   1 
ATOM   2048 C  CA  . MET B 1 87  ? 32.359  -40.215 56.783  1.00 49.40  ? 87  MET A CA  1 
ATOM   2049 C  C   . MET B 1 87  ? 30.908  -40.047 57.192  1.00 48.38  ? 87  MET A C   1 
ATOM   2050 O  O   . MET B 1 87  ? 30.376  -38.937 57.277  1.00 54.19  ? 87  MET A O   1 
ATOM   2051 C  CB  . MET B 1 87  ? 33.153  -40.779 57.946  1.00 59.55  ? 87  MET A CB  1 
ATOM   2052 C  CG  . MET B 1 87  ? 34.511  -41.263 57.530  1.00 65.04  ? 87  MET A CG  1 
ATOM   2053 S  SD  . MET B 1 87  ? 35.591  -40.869 58.866  1.00 75.90  ? 87  MET A SD  1 
ATOM   2054 C  CE  . MET B 1 87  ? 35.210  -42.289 59.896  1.00 65.40  ? 87  MET A CE  1 
ATOM   2055 N  N   . ARG B 1 88  ? 30.265  -41.184 57.427  1.00 48.33  ? 88  ARG A N   1 
ATOM   2056 C  CA  . ARG B 1 88  ? 28.945  -41.216 58.035  1.00 49.12  ? 88  ARG A CA  1 
ATOM   2057 C  C   . ARG B 1 88  ? 29.015  -41.406 59.546  1.00 48.92  ? 88  ARG A C   1 
ATOM   2058 O  O   . ARG B 1 88  ? 28.100  -40.980 60.266  1.00 44.59  ? 88  ARG A O   1 
ATOM   2059 C  CB  . ARG B 1 88  ? 28.121  -42.341 57.395  1.00 59.10  ? 88  ARG A CB  1 
ATOM   2060 C  CG  . ARG B 1 88  ? 28.382  -42.554 55.880  1.00 49.41  ? 88  ARG A CG  1 
ATOM   2061 C  CD  . ARG B 1 88  ? 27.289  -41.871 55.055  1.00 52.61  ? 88  ARG A CD  1 
ATOM   2062 N  NE  . ARG B 1 88  ? 27.087  -40.508 55.514  1.00 49.97  ? 88  ARG A NE  1 
ATOM   2063 C  CZ  . ARG B 1 88  ? 27.783  -39.477 55.044  1.00 60.27  ? 88  ARG A CZ  1 
ATOM   2064 N  NH1 . ARG B 1 88  ? 27.599  -38.247 55.539  1.00 57.90  ? 88  ARG A NH1 1 
ATOM   2065 N  NH2 . ARG B 1 88  ? 28.679  -39.682 54.079  1.00 56.03  ? 88  ARG A NH2 1 
ATOM   2066 N  N   . GLU B 1 89  ? 30.085  -42.040 60.026  1.00 42.66  ? 89  GLU A N   1 
ATOM   2067 C  CA  . GLU B 1 89  ? 30.267  -42.397 61.421  1.00 48.83  ? 89  GLU A CA  1 
ATOM   2068 C  C   . GLU B 1 89  ? 31.456  -41.620 61.961  1.00 49.01  ? 89  GLU A C   1 
ATOM   2069 O  O   . GLU B 1 89  ? 32.546  -41.665 61.383  1.00 45.29  ? 89  GLU A O   1 
ATOM   2070 C  CB  . GLU B 1 89  ? 30.515  -43.898 61.579  1.00 52.14  ? 89  GLU A CB  1 
ATOM   2071 C  CG  . GLU B 1 89  ? 29.382  -44.783 61.150  1.00 60.85  ? 89  GLU A CG  1 
ATOM   2072 C  CD  . GLU B 1 89  ? 29.166  -45.922 62.131  1.00 72.40  ? 89  GLU A CD  1 
ATOM   2073 O  OE1 . GLU B 1 89  ? 29.706  -45.841 63.257  1.00 75.31  ? 89  GLU A OE1 1 
ATOM   2074 O  OE2 . GLU B 1 89  ? 28.463  -46.894 61.783  1.00 77.19  ? 89  GLU A OE2 1 
ATOM   2075 N  N   . TRP B 1 90  ? 31.255  -40.904 63.060  1.00 40.40  ? 90  TRP A N   1 
ATOM   2076 C  CA  . TRP B 1 90  ? 32.295  -39.992 63.499  1.00 46.15  ? 90  TRP A CA  1 
ATOM   2077 C  C   . TRP B 1 90  ? 33.038  -40.491 64.720  1.00 37.77  ? 90  TRP A C   1 
ATOM   2078 O  O   . TRP B 1 90  ? 34.053  -39.896 65.076  1.00 38.85  ? 90  TRP A O   1 
ATOM   2079 C  CB  . TRP B 1 90  ? 31.706  -38.586 63.740  1.00 39.25  ? 90  TRP A CB  1 
ATOM   2080 C  CG  . TRP B 1 90  ? 31.188  -38.031 62.455  1.00 37.27  ? 90  TRP A CG  1 
ATOM   2081 C  CD1 . TRP B 1 90  ? 29.891  -38.052 62.003  1.00 44.00  ? 90  TRP A CD1 1 
ATOM   2082 C  CD2 . TRP B 1 90  ? 31.962  -37.436 61.410  1.00 36.87  ? 90  TRP A CD2 1 
ATOM   2083 N  NE1 . TRP B 1 90  ? 29.813  -37.483 60.746  1.00 38.96  ? 90  TRP A NE1 1 
ATOM   2084 C  CE2 . TRP B 1 90  ? 31.069  -37.091 60.367  1.00 36.38  ? 90  TRP A CE2 1 
ATOM   2085 C  CE3 . TRP B 1 90  ? 33.323  -37.129 61.267  1.00 35.47  ? 90  TRP A CE3 1 
ATOM   2086 C  CZ2 . TRP B 1 90  ? 31.496  -36.473 59.198  1.00 38.90  ? 90  TRP A CZ2 1 
ATOM   2087 C  CZ3 . TRP B 1 90  ? 33.747  -36.515 60.111  1.00 29.88  ? 90  TRP A CZ3 1 
ATOM   2088 C  CH2 . TRP B 1 90  ? 32.836  -36.200 59.084  1.00 43.98  ? 90  TRP A CH2 1 
ATOM   2089 N  N   . GLY B 1 91  ? 32.586  -41.586 65.333  1.00 40.54  ? 91  GLY A N   1 
ATOM   2090 C  CA  . GLY B 1 91  ? 33.288  -42.219 66.438  1.00 38.70  ? 91  GLY A CA  1 
ATOM   2091 C  C   . GLY B 1 91  ? 32.990  -41.615 67.795  1.00 42.14  ? 91  GLY A C   1 
ATOM   2092 O  O   . GLY B 1 91  ? 31.835  -41.333 68.129  1.00 45.49  ? 91  GLY A O   1 
ATOM   2093 N  N   . THR B 1 92  ? 34.028  -41.412 68.595  1.00 47.63  ? 92  THR A N   1 
ATOM   2094 C  CA  . THR B 1 92  ? 33.853  -40.785 69.896  1.00 46.78  ? 92  THR A CA  1 
ATOM   2095 C  C   . THR B 1 92  ? 33.665  -39.285 69.729  1.00 41.54  ? 92  THR A C   1 
ATOM   2096 O  O   . THR B 1 92  ? 33.971  -38.709 68.681  1.00 44.16  ? 92  THR A O   1 
ATOM   2097 C  CB  . THR B 1 92  ? 35.064  -41.054 70.782  1.00 43.24  ? 92  THR A CB  1 
ATOM   2098 O  OG1 . THR B 1 92  ? 36.211  -40.458 70.174  1.00 49.59  ? 92  THR A OG1 1 
ATOM   2099 C  CG2 . THR B 1 92  ? 35.317  -42.554 70.876  1.00 40.86  ? 92  THR A CG2 1 
ATOM   2100 N  N   . GLY B 1 93  ? 33.137  -38.649 70.771  1.00 41.33  ? 93  GLY A N   1 
ATOM   2101 C  CA  . GLY B 1 93  ? 33.058  -37.200 70.765  1.00 41.52  ? 93  GLY A CA  1 
ATOM   2102 C  C   . GLY B 1 93  ? 34.408  -36.550 70.538  1.00 41.01  ? 93  GLY A C   1 
ATOM   2103 O  O   . GLY B 1 93  ? 34.494  -35.473 69.935  1.00 40.19  ? 93  GLY A O   1 
ATOM   2104 N  N   . LEU B 1 94  ? 35.476  -37.198 70.998  1.00 40.72  ? 94  LEU A N   1 
ATOM   2105 C  CA  . LEU B 1 94  ? 36.811  -36.642 70.826  1.00 41.78  ? 94  LEU A CA  1 
ATOM   2106 C  C   . LEU B 1 94  ? 37.237  -36.712 69.368  1.00 42.96  ? 94  LEU A C   1 
ATOM   2107 O  O   . LEU B 1 94  ? 37.705  -35.720 68.797  1.00 45.22  ? 94  LEU A O   1 
ATOM   2108 C  CB  . LEU B 1 94  ? 37.810  -37.385 71.717  1.00 34.21  ? 94  LEU A CB  1 
ATOM   2109 C  CG  . LEU B 1 94  ? 39.266  -36.995 71.481  1.00 41.31  ? 94  LEU A CG  1 
ATOM   2110 C  CD1 . LEU B 1 94  ? 39.452  -35.495 71.703  1.00 39.04  ? 94  LEU A CD1 1 
ATOM   2111 C  CD2 . LEU B 1 94  ? 40.171  -37.790 72.397  1.00 39.18  ? 94  LEU A CD2 1 
ATOM   2112 N  N   . GLU B 1 95  ? 37.073  -37.881 68.746  1.00 44.18  ? 95  GLU A N   1 
ATOM   2113 C  CA  . GLU B 1 95  ? 37.382  -38.019 67.325  1.00 42.82  ? 95  GLU A CA  1 
ATOM   2114 C  C   . GLU B 1 95  ? 36.569  -37.050 66.481  1.00 38.09  ? 95  GLU A C   1 
ATOM   2115 O  O   . GLU B 1 95  ? 37.064  -36.535 65.474  1.00 39.51  ? 95  GLU A O   1 
ATOM   2116 C  CB  . GLU B 1 95  ? 37.131  -39.449 66.872  1.00 40.34  ? 95  GLU A CB  1 
ATOM   2117 C  CG  . GLU B 1 95  ? 38.137  -40.451 67.410  1.00 44.18  ? 95  GLU A CG  1 
ATOM   2118 C  CD  . GLU B 1 95  ? 37.709  -41.888 67.134  1.00 54.98  ? 95  GLU A CD  1 
ATOM   2119 O  OE1 . GLU B 1 95  ? 36.551  -42.240 67.486  1.00 53.80  ? 95  GLU A OE1 1 
ATOM   2120 O  OE2 . GLU B 1 95  ? 38.520  -42.651 66.551  1.00 53.18  ? 95  GLU A OE2 1 
ATOM   2121 N  N   . ALA B 1 96  ? 35.326  -36.766 66.884  1.00 32.40  ? 96  ALA A N   1 
ATOM   2122 C  CA  . ALA B 1 96  ? 34.518  -35.835 66.108  1.00 35.92  ? 96  ALA A CA  1 
ATOM   2123 C  C   . ALA B 1 96  ? 35.060  -34.414 66.228  1.00 42.13  ? 96  ALA A C   1 
ATOM   2124 O  O   . ALA B 1 96  ? 35.063  -33.650 65.245  1.00 36.79  ? 96  ALA A O   1 
ATOM   2125 C  CB  . ALA B 1 96  ? 33.058  -35.901 66.551  1.00 31.69  ? 96  ALA A CB  1 
ATOM   2126 N  N   . LEU B 1 97  ? 35.525  -34.042 67.424  1.00 36.01  ? 97  LEU A N   1 
ATOM   2127 C  CA  . LEU B 1 97  ? 36.096  -32.714 67.604  1.00 39.76  ? 97  LEU A CA  1 
ATOM   2128 C  C   . LEU B 1 97  ? 37.383  -32.575 66.809  1.00 41.09  ? 97  LEU A C   1 
ATOM   2129 O  O   . LEU B 1 97  ? 37.616  -31.538 66.185  1.00 44.42  ? 97  LEU A O   1 
ATOM   2130 C  CB  . LEU B 1 97  ? 36.352  -32.434 69.085  1.00 43.25  ? 97  LEU A CB  1 
ATOM   2131 C  CG  . LEU B 1 97  ? 35.129  -32.259 69.989  1.00 42.53  ? 97  LEU A CG  1 
ATOM   2132 C  CD1 . LEU B 1 97  ? 35.549  -32.096 71.455  1.00 37.56  ? 97  LEU A CD1 1 
ATOM   2133 C  CD2 . LEU B 1 97  ? 34.317  -31.067 69.522  1.00 36.42  ? 97  LEU A CD2 1 
ATOM   2134 N  N   . GLN B 1 98  ? 38.224  -33.617 66.801  1.00 39.36  ? 98  GLN A N   1 
ATOM   2135 C  CA  . GLN B 1 98  ? 39.451  -33.545 66.015  1.00 41.29  ? 98  GLN A CA  1 
ATOM   2136 C  C   . GLN B 1 98  ? 39.134  -33.420 64.532  1.00 43.95  ? 98  GLN A C   1 
ATOM   2137 O  O   . GLN B 1 98  ? 39.772  -32.631 63.823  1.00 38.99  ? 98  GLN A O   1 
ATOM   2138 C  CB  . GLN B 1 98  ? 40.352  -34.752 66.309  1.00 37.13  ? 98  GLN A CB  1 
ATOM   2139 C  CG  . GLN B 1 98  ? 40.506  -34.971 67.823  1.00 52.89  ? 98  GLN A CG  1 
ATOM   2140 C  CD  . GLN B 1 98  ? 41.400  -36.145 68.228  1.00 60.70  ? 98  GLN A CD  1 
ATOM   2141 O  OE1 . GLN B 1 98  ? 42.408  -35.950 68.923  1.00 55.04  ? 98  GLN A OE1 1 
ATOM   2142 N  NE2 . GLN B 1 98  ? 41.020  -37.372 67.825  1.00 48.24  ? 98  GLN A NE2 1 
ATOM   2143 N  N   . ALA B 1 99  ? 38.120  -34.149 64.046  1.00 39.75  ? 99  ALA A N   1 
ATOM   2144 C  CA  . ALA B 1 99  ? 37.699  -33.944 62.666  1.00 35.99  ? 99  ALA A CA  1 
ATOM   2145 C  C   . ALA B 1 99  ? 37.177  -32.527 62.460  1.00 36.52  ? 99  ALA A C   1 
ATOM   2146 O  O   . ALA B 1 99  ? 37.423  -31.919 61.417  1.00 42.38  ? 99  ALA A O   1 
ATOM   2147 C  CB  . ALA B 1 99  ? 36.645  -34.972 62.265  1.00 37.06  ? 99  ALA A CB  1 
ATOM   2148 N  N   . ALA B 1 100 ? 36.487  -31.969 63.456  1.00 36.35  ? 100 ALA A N   1 
ATOM   2149 C  CA  . ALA B 1 100 ? 35.980  -30.603 63.317  1.00 40.94  ? 100 ALA A CA  1 
ATOM   2150 C  C   . ALA B 1 100 ? 37.114  -29.580 63.340  1.00 43.89  ? 100 ALA A C   1 
ATOM   2151 O  O   . ALA B 1 100 ? 37.098  -28.610 62.566  1.00 43.66  ? 100 ALA A O   1 
ATOM   2152 C  CB  . ALA B 1 100 ? 34.960  -30.300 64.413  1.00 36.90  ? 100 ALA A CB  1 
ATOM   2153 N  N   . LEU B 1 101 ? 38.106  -29.776 64.220  1.00 41.48  ? 101 LEU A N   1 
ATOM   2154 C  CA  . LEU B 1 101 ? 39.269  -28.891 64.240  1.00 40.86  ? 101 LEU A CA  1 
ATOM   2155 C  C   . LEU B 1 101 ? 39.970  -28.856 62.878  1.00 48.03  ? 101 LEU A C   1 
ATOM   2156 O  O   . LEU B 1 101 ? 40.383  -27.788 62.411  1.00 49.65  ? 101 LEU A O   1 
ATOM   2157 C  CB  . LEU B 1 101 ? 40.240  -29.330 65.330  1.00 37.71  ? 101 LEU A CB  1 
ATOM   2158 C  CG  . LEU B 1 101 ? 41.442  -28.401 65.566  1.00 49.00  ? 101 LEU A CG  1 
ATOM   2159 C  CD1 . LEU B 1 101 ? 40.984  -27.021 66.065  1.00 45.34  ? 101 LEU A CD1 1 
ATOM   2160 C  CD2 . LEU B 1 101 ? 42.449  -29.021 66.523  1.00 35.96  ? 101 LEU A CD2 1 
ATOM   2161 N  N   . ASP B 1 102 ? 40.092  -30.012 62.222  1.00 41.19  ? 102 ASP A N   1 
ATOM   2162 C  CA  . ASP B 1 102 ? 40.716  -30.068 60.908  1.00 44.82  ? 102 ASP A CA  1 
ATOM   2163 C  C   . ASP B 1 102 ? 39.818  -29.452 59.841  1.00 45.68  ? 102 ASP A C   1 
ATOM   2164 O  O   . ASP B 1 102 ? 40.304  -28.764 58.936  1.00 43.90  ? 102 ASP A O   1 
ATOM   2165 C  CB  . ASP B 1 102 ? 41.059  -31.513 60.545  1.00 36.84  ? 102 ASP A CB  1 
ATOM   2166 C  CG  . ASP B 1 102 ? 42.108  -32.113 61.468  1.00 58.02  ? 102 ASP A CG  1 
ATOM   2167 O  OD1 . ASP B 1 102 ? 42.947  -31.353 62.019  1.00 64.47  ? 102 ASP A OD1 1 
ATOM   2168 O  OD2 . ASP B 1 102 ? 42.096  -33.352 61.645  1.00 60.62  ? 102 ASP A OD2 1 
ATOM   2169 N  N   . LEU B 1 103 ? 38.513  -29.702 59.914  1.00 41.24  ? 103 LEU A N   1 
ATOM   2170 C  CA  . LEU B 1 103 ? 37.607  -29.054 58.973  1.00 44.48  ? 103 LEU A CA  1 
ATOM   2171 C  C   . LEU B 1 103 ? 37.709  -27.538 59.089  1.00 44.77  ? 103 LEU A C   1 
ATOM   2172 O  O   . LEU B 1 103 ? 37.732  -26.827 58.079  1.00 46.01  ? 103 LEU A O   1 
ATOM   2173 C  CB  . LEU B 1 103 ? 36.173  -29.527 59.211  1.00 37.92  ? 103 LEU A CB  1 
ATOM   2174 C  CG  . LEU B 1 103 ? 35.115  -28.806 58.367  1.00 45.24  ? 103 LEU A CG  1 
ATOM   2175 C  CD1 . LEU B 1 103 ? 35.118  -29.348 56.942  1.00 39.56  ? 103 LEU A CD1 1 
ATOM   2176 C  CD2 . LEU B 1 103 ? 33.710  -28.881 58.988  1.00 39.99  ? 103 LEU A CD2 1 
ATOM   2177 N  N   . GLU B 1 104 ? 37.827  -27.034 60.316  1.00 45.45  ? 104 GLU A N   1 
ATOM   2178 C  CA  . GLU B 1 104 ? 37.887  -25.595 60.533  1.00 49.18  ? 104 GLU A CA  1 
ATOM   2179 C  C   . GLU B 1 104 ? 39.178  -25.010 59.989  1.00 55.22  ? 104 GLU A C   1 
ATOM   2180 O  O   . GLU B 1 104 ? 39.169  -23.936 59.378  1.00 57.46  ? 104 GLU A O   1 
ATOM   2181 C  CB  . GLU B 1 104 ? 37.755  -25.287 62.021  1.00 49.96  ? 104 GLU A CB  1 
ATOM   2182 C  CG  . GLU B 1 104 ? 36.363  -25.475 62.565  1.00 53.21  ? 104 GLU A CG  1 
ATOM   2183 C  CD  . GLU B 1 104 ? 35.388  -24.407 62.091  1.00 61.15  ? 104 GLU A CD  1 
ATOM   2184 O  OE1 . GLU B 1 104 ? 34.204  -24.752 61.880  1.00 60.23  ? 104 GLU A OE1 1 
ATOM   2185 O  OE2 . GLU B 1 104 ? 35.796  -23.228 61.952  1.00 71.53  ? 104 GLU A OE2 1 
ATOM   2186 N  N   . LYS B 1 105 ? 40.300  -25.695 60.212  1.00 58.00  ? 105 LYS A N   1 
ATOM   2187 C  CA  . LYS B 1 105 ? 41.572  -25.201 59.698  1.00 51.07  ? 105 LYS A CA  1 
ATOM   2188 C  C   . LYS B 1 105 ? 41.600  -25.238 58.178  1.00 53.77  ? 105 LYS A C   1 
ATOM   2189 O  O   . LYS B 1 105 ? 42.105  -24.306 57.545  1.00 57.10  ? 105 LYS A O   1 
ATOM   2190 C  CB  . LYS B 1 105 ? 42.728  -26.010 60.273  1.00 43.38  ? 105 LYS A CB  1 
ATOM   2191 C  CG  . LYS B 1 105 ? 43.019  -25.753 61.754  1.00 43.36  ? 105 LYS A CG  1 
ATOM   2192 C  CD  . LYS B 1 105 ? 44.266  -26.549 62.156  1.00 49.93  ? 105 LYS A CD  1 
ATOM   2193 C  CE  . LYS B 1 105 ? 44.384  -26.814 63.647  1.00 56.91  ? 105 LYS A CE  1 
ATOM   2194 N  NZ  . LYS B 1 105 ? 45.277  -28.003 63.863  1.00 55.24  ? 105 LYS A NZ  1 
ATOM   2195 N  N   . GLN B 1 106 ? 41.053  -26.293 57.568  1.00 51.96  ? 106 GLN A N   1 
ATOM   2196 C  CA  . GLN B 1 106 ? 41.036  -26.339 56.111  1.00 50.87  ? 106 GLN A CA  1 
ATOM   2197 C  C   . GLN B 1 106 ? 40.041  -25.361 55.499  1.00 55.34  ? 106 GLN A C   1 
ATOM   2198 O  O   . GLN B 1 106 ? 40.074  -25.178 54.280  1.00 66.48  ? 106 GLN A O   1 
ATOM   2199 C  CB  . GLN B 1 106 ? 40.737  -27.756 55.603  1.00 48.25  ? 106 GLN A CB  1 
ATOM   2200 C  CG  . GLN B 1 106 ? 39.257  -28.083 55.532  1.00 59.67  ? 106 GLN A CG  1 
ATOM   2201 C  CD  . GLN B 1 106 ? 38.956  -29.429 54.859  1.00 70.19  ? 106 GLN A CD  1 
ATOM   2202 O  OE1 . GLN B 1 106 ? 38.662  -30.424 55.539  1.00 61.88  ? 106 GLN A OE1 1 
ATOM   2203 N  NE2 . GLN B 1 106 ? 38.985  -29.453 53.523  1.00 60.63  ? 106 GLN A NE2 1 
ATOM   2204 N  N   . VAL B 1 107 ? 39.155  -24.746 56.288  1.00 55.54  ? 107 VAL A N   1 
ATOM   2205 C  CA  . VAL B 1 107 ? 38.323  -23.656 55.771  1.00 52.23  ? 107 VAL A CA  1 
ATOM   2206 C  C   . VAL B 1 107 ? 39.029  -22.316 55.928  1.00 53.87  ? 107 VAL A C   1 
ATOM   2207 O  O   . VAL B 1 107 ? 39.023  -21.489 55.013  1.00 53.41  ? 107 VAL A O   1 
ATOM   2208 C  CB  . VAL B 1 107 ? 36.938  -23.645 56.457  1.00 50.94  ? 107 VAL A CB  1 
ATOM   2209 C  CG1 . VAL B 1 107 ? 36.196  -22.310 56.191  1.00 46.17  ? 107 VAL A CG1 1 
ATOM   2210 C  CG2 . VAL B 1 107 ? 36.100  -24.800 55.975  1.00 42.23  ? 107 VAL A CG2 1 
ATOM   2211 N  N   . ASN B 1 108 ? 39.651  -22.098 57.086  1.00 51.77  ? 108 ASN A N   1 
ATOM   2212 C  CA  . ASN B 1 108 ? 40.475  -20.913 57.283  1.00 59.16  ? 108 ASN A CA  1 
ATOM   2213 C  C   . ASN B 1 108 ? 41.686  -20.913 56.361  1.00 60.10  ? 108 ASN A C   1 
ATOM   2214 O  O   . ASN B 1 108 ? 42.139  -19.847 55.931  1.00 63.69  ? 108 ASN A O   1 
ATOM   2215 C  CB  . ASN B 1 108 ? 40.910  -20.826 58.744  1.00 56.99  ? 108 ASN A CB  1 
ATOM   2216 C  CG  . ASN B 1 108 ? 39.748  -20.579 59.663  1.00 70.65  ? 108 ASN A CG  1 
ATOM   2217 O  OD1 . ASN B 1 108 ? 38.646  -20.281 59.203  1.00 78.78  ? 108 ASN A OD1 1 
ATOM   2218 N  ND2 . ASN B 1 108 ? 39.972  -20.710 60.965  1.00 82.27  ? 108 ASN A ND2 1 
ATOM   2219 N  N   . GLN B 1 109 ? 42.229  -22.089 56.052  1.00 57.06  ? 109 GLN A N   1 
ATOM   2220 C  CA  . GLN B 1 109 ? 43.331  -22.156 55.101  1.00 59.44  ? 109 GLN A CA  1 
ATOM   2221 C  C   . GLN B 1 109 ? 42.882  -21.691 53.725  1.00 61.23  ? 109 GLN A C   1 
ATOM   2222 O  O   . GLN B 1 109 ? 43.579  -20.917 53.060  1.00 58.05  ? 109 GLN A O   1 
ATOM   2223 C  CB  . GLN B 1 109 ? 43.878  -23.582 55.033  1.00 60.23  ? 109 GLN A CB  1 
ATOM   2224 C  CG  . GLN B 1 109 ? 44.977  -23.798 54.032  1.00 49.59  ? 109 GLN A CG  1 
ATOM   2225 C  CD  . GLN B 1 109 ? 46.136  -22.838 54.210  1.00 69.40  ? 109 GLN A CD  1 
ATOM   2226 O  OE1 . GLN B 1 109 ? 46.444  -22.376 55.326  1.00 65.06  ? 109 GLN A OE1 1 
ATOM   2227 N  NE2 . GLN B 1 109 ? 46.803  -22.539 53.102  1.00 67.39  ? 109 GLN A NE2 1 
ATOM   2228 N  N   . SER B 1 110 ? 41.712  -22.153 53.283  1.00 58.08  ? 110 SER A N   1 
ATOM   2229 C  CA  . SER B 1 110 ? 41.171  -21.666 52.026  1.00 54.93  ? 110 SER A CA  1 
ATOM   2230 C  C   . SER B 1 110 ? 40.944  -20.159 52.096  1.00 58.62  ? 110 SER A C   1 
ATOM   2231 O  O   . SER B 1 110 ? 41.175  -19.443 51.116  1.00 56.87  ? 110 SER A O   1 
ATOM   2232 C  CB  . SER B 1 110 ? 39.887  -22.431 51.709  1.00 53.63  ? 110 SER A CB  1 
ATOM   2233 O  OG  . SER B 1 110 ? 39.138  -21.805 50.693  1.00 53.69  ? 110 SER A OG  1 
ATOM   2234 N  N   . LEU B 1 111 ? 40.542  -19.660 53.274  1.00 57.14  ? 111 LEU A N   1 
ATOM   2235 C  CA  . LEU B 1 111 ? 40.351  -18.227 53.484  1.00 52.41  ? 111 LEU A CA  1 
ATOM   2236 C  C   . LEU B 1 111 ? 41.643  -17.450 53.250  1.00 60.05  ? 111 LEU A C   1 
ATOM   2237 O  O   . LEU B 1 111 ? 41.639  -16.404 52.587  1.00 54.68  ? 111 LEU A O   1 
ATOM   2238 C  CB  . LEU B 1 111 ? 39.841  -17.983 54.905  1.00 53.49  ? 111 LEU A CB  1 
ATOM   2239 C  CG  . LEU B 1 111 ? 38.358  -17.737 55.158  1.00 59.77  ? 111 LEU A CG  1 
ATOM   2240 C  CD1 . LEU B 1 111 ? 38.113  -17.509 56.635  1.00 68.83  ? 111 LEU A CD1 1 
ATOM   2241 C  CD2 . LEU B 1 111 ? 37.896  -16.537 54.368  1.00 58.05  ? 111 LEU A CD2 1 
ATOM   2242 N  N   . LEU B 1 112 ? 42.756  -17.938 53.818  1.00 58.41  ? 112 LEU A N   1 
ATOM   2243 C  CA  . LEU B 1 112 ? 44.035  -17.243 53.699  1.00 59.57  ? 112 LEU A CA  1 
ATOM   2244 C  C   . LEU B 1 112 ? 44.491  -17.161 52.250  1.00 64.16  ? 112 LEU A C   1 
ATOM   2245 O  O   . LEU B 1 112 ? 45.017  -16.128 51.821  1.00 68.42  ? 112 LEU A O   1 
ATOM   2246 C  CB  . LEU B 1 112 ? 45.103  -17.948 54.527  1.00 59.60  ? 112 LEU A CB  1 
ATOM   2247 C  CG  . LEU B 1 112 ? 45.188  -17.614 56.004  1.00 68.21  ? 112 LEU A CG  1 
ATOM   2248 C  CD1 . LEU B 1 112 ? 46.100  -18.618 56.660  1.00 70.31  ? 112 LEU A CD1 1 
ATOM   2249 C  CD2 . LEU B 1 112 ? 45.694  -16.205 56.199  1.00 65.99  ? 112 LEU A CD2 1 
ATOM   2250 N  N   . GLU B 1 113 ? 44.338  -18.256 51.492  1.00 56.01  ? 113 GLU A N   1 
ATOM   2251 C  CA  . GLU B 1 113 ? 44.616  -18.209 50.062  1.00 59.14  ? 113 GLU A CA  1 
ATOM   2252 C  C   . GLU B 1 113 ? 43.798  -17.107 49.401  1.00 64.53  ? 113 GLU A C   1 
ATOM   2253 O  O   . GLU B 1 113 ? 44.305  -16.358 48.556  1.00 70.18  ? 113 GLU A O   1 
ATOM   2254 C  CB  . GLU B 1 113 ? 44.318  -19.564 49.412  1.00 58.70  ? 113 GLU A CB  1 
ATOM   2255 C  CG  . GLU B 1 113 ? 45.225  -20.720 49.846  1.00 60.06  ? 113 GLU A CG  1 
ATOM   2256 C  CD  . GLU B 1 113 ? 44.619  -22.110 49.561  1.00 62.79  ? 113 GLU A CD  1 
ATOM   2257 O  OE1 . GLU B 1 113 ? 44.753  -23.000 50.426  1.00 61.90  ? 113 GLU A OE1 1 
ATOM   2258 O  OE2 . GLU B 1 113 ? 44.015  -22.320 48.479  1.00 66.28  ? 113 GLU A OE2 1 
ATOM   2259 N  N   . LEU B 1 114 ? 42.540  -16.962 49.807  1.00 60.63  ? 114 LEU A N   1 
ATOM   2260 C  CA  . LEU B 1 114 ? 41.713  -15.908 49.242  1.00 62.21  ? 114 LEU A CA  1 
ATOM   2261 C  C   . LEU B 1 114 ? 42.133  -14.534 49.757  1.00 65.06  ? 114 LEU A C   1 
ATOM   2262 O  O   . LEU B 1 114 ? 41.967  -13.535 49.044  1.00 66.69  ? 114 LEU A O   1 
ATOM   2263 C  CB  . LEU B 1 114 ? 40.243  -16.222 49.526  1.00 56.08  ? 114 LEU A CB  1 
ATOM   2264 C  CG  . LEU B 1 114 ? 39.163  -15.154 49.443  1.00 57.06  ? 114 LEU A CG  1 
ATOM   2265 C  CD1 . LEU B 1 114 ? 38.974  -14.692 48.006  1.00 55.61  ? 114 LEU A CD1 1 
ATOM   2266 C  CD2 . LEU B 1 114 ? 37.847  -15.701 49.996  1.00 48.74  ? 114 LEU A CD2 1 
ATOM   2267 N  N   . HIS B 1 115 ? 42.727  -14.470 50.959  1.00 65.03  ? 115 HIS A N   1 
ATOM   2268 C  CA  . HIS B 1 115 ? 43.221  -13.197 51.489  1.00 66.99  ? 115 HIS A CA  1 
ATOM   2269 C  C   . HIS B 1 115 ? 44.403  -12.662 50.679  1.00 69.59  ? 115 HIS A C   1 
ATOM   2270 O  O   . HIS B 1 115 ? 44.466  -11.460 50.388  1.00 69.03  ? 115 HIS A O   1 
ATOM   2271 C  CB  . HIS B 1 115 ? 43.621  -13.338 52.957  1.00 53.91  ? 115 HIS A CB  1 
ATOM   2272 C  CG  . HIS B 1 115 ? 44.118  -12.063 53.570  1.00 61.25  ? 115 HIS A CG  1 
ATOM   2273 N  ND1 . HIS B 1 115 ? 45.460  -11.766 53.699  1.00 64.03  ? 115 HIS A ND1 1 
ATOM   2274 C  CD2 . HIS B 1 115 ? 43.448  -11.002 54.084  1.00 65.84  ? 115 HIS A CD2 1 
ATOM   2275 C  CE1 . HIS B 1 115 ? 45.593  -10.580 54.268  1.00 62.38  ? 115 HIS A CE1 1 
ATOM   2276 N  NE2 . HIS B 1 115 ? 44.388  -10.097 54.517  1.00 65.09  ? 115 HIS A NE2 1 
ATOM   2277 N  N   . SER B 1 116 ? 45.357  -13.527 50.317  1.00 67.33  ? 116 SER A N   1 
ATOM   2278 C  CA  . SER B 1 116 ? 46.471  -13.058 49.501  1.00 69.52  ? 116 SER A CA  1 
ATOM   2279 C  C   . SER B 1 116 ? 46.017  -12.676 48.094  1.00 67.27  ? 116 SER A C   1 
ATOM   2280 O  O   . SER B 1 116 ? 46.532  -11.708 47.520  1.00 65.49  ? 116 SER A O   1 
ATOM   2281 C  CB  . SER B 1 116 ? 47.572  -14.114 49.449  1.00 66.83  ? 116 SER A CB  1 
ATOM   2282 O  OG  . SER B 1 116 ? 48.843  -13.485 49.324  1.00 81.10  ? 116 SER A OG  1 
ATOM   2283 N  N   . THR B 1 117 ? 45.048  -13.410 47.534  1.00 68.36  ? 117 THR A N   1 
ATOM   2284 C  CA  . THR B 1 117 ? 44.508  -13.054 46.223  1.00 72.96  ? 117 THR A CA  1 
ATOM   2285 C  C   . THR B 1 117 ? 43.927  -11.645 46.236  1.00 67.16  ? 117 THR A C   1 
ATOM   2286 O  O   . THR B 1 117 ? 44.192  -10.844 45.332  1.00 65.56  ? 117 THR A O   1 
ATOM   2287 C  CB  . THR B 1 117 ? 43.442  -14.068 45.787  1.00 67.50  ? 117 THR A CB  1 
ATOM   2288 O  OG1 . THR B 1 117 ? 44.013  -15.381 45.747  1.00 68.55  ? 117 THR A OG1 1 
ATOM   2289 C  CG2 . THR B 1 117 ? 42.907  -13.731 44.398  1.00 54.53  ? 117 THR A CG2 1 
ATOM   2290 N  N   . ALA B 1 118 ? 43.148  -11.318 47.265  1.00 63.77  ? 118 ALA A N   1 
ATOM   2291 C  CA  . ALA B 1 118 ? 42.596  -9.974  47.357  1.00 63.53  ? 118 ALA A CA  1 
ATOM   2292 C  C   . ALA B 1 118 ? 43.686  -8.926  47.574  1.00 69.29  ? 118 ALA A C   1 
ATOM   2293 O  O   . ALA B 1 118 ? 43.567  -7.796  47.083  1.00 68.97  ? 118 ALA A O   1 
ATOM   2294 C  CB  . ALA B 1 118 ? 41.563  -9.925  48.475  1.00 61.36  ? 118 ALA A CB  1 
ATOM   2295 N  N   . SER B 1 119 ? 44.760  -9.284  48.286  1.00 71.05  ? 119 SER A N   1 
ATOM   2296 C  CA  . SER B 1 119 ? 45.815  -8.320  48.583  1.00 73.28  ? 119 SER A CA  1 
ATOM   2297 C  C   . SER B 1 119 ? 46.745  -8.103  47.387  1.00 70.20  ? 119 SER A C   1 
ATOM   2298 O  O   . SER B 1 119 ? 47.194  -6.974  47.151  1.00 68.93  ? 119 SER A O   1 
ATOM   2299 C  CB  . SER B 1 119 ? 46.597  -8.775  49.816  1.00 66.08  ? 119 SER A CB  1 
ATOM   2300 O  OG  . SER B 1 119 ? 47.890  -8.196  49.840  1.00 83.73  ? 119 SER A OG  1 
ATOM   2301 N  N   . GLY B 1 120 ? 47.048  -9.164  46.627  1.00 68.74  ? 120 GLY A N   1 
ATOM   2302 C  CA  . GLY B 1 120 ? 47.758  -9.028  45.361  1.00 64.84  ? 120 GLY A CA  1 
ATOM   2303 C  C   . GLY B 1 120 ? 46.929  -8.475  44.220  1.00 65.50  ? 120 GLY A C   1 
ATOM   2304 O  O   . GLY B 1 120 ? 47.408  -8.410  43.087  1.00 68.23  ? 120 GLY A O   1 
ATOM   2305 N  N   . ASN B 1 121 ? 45.679  -8.105  44.481  1.00 71.05  ? 121 ASN A N   1 
ATOM   2306 C  CA  . ASN B 1 121 ? 44.848  -7.411  43.509  1.00 67.23  ? 121 ASN A CA  1 
ATOM   2307 C  C   . ASN B 1 121 ? 44.437  -6.044  44.026  1.00 70.78  ? 121 ASN A C   1 
ATOM   2308 O  O   . ASN B 1 121 ? 43.621  -5.364  43.386  1.00 72.97  ? 121 ASN A O   1 
ATOM   2309 C  CB  . ASN B 1 121 ? 43.613  -8.246  43.155  1.00 66.29  ? 121 ASN A CB  1 
ATOM   2310 C  CG  . ASN B 1 121 ? 43.886  -9.248  42.044  1.00 65.93  ? 121 ASN A CG  1 
ATOM   2311 O  OD1 . ASN B 1 121 ? 44.674  -8.981  41.137  1.00 73.22  ? 121 ASN A OD1 1 
ATOM   2312 N  ND2 . ASN B 1 121 ? 43.235  -10.406 42.110  1.00 64.44  ? 121 ASN A ND2 1 
ATOM   2313 N  N   . ASN B 1 122 ? 45.002  -5.622  45.161  1.00 70.43  ? 122 ASN A N   1 
ATOM   2314 C  CA  . ASN B 1 122 ? 44.657  -4.366  45.815  1.00 72.43  ? 122 ASN A CA  1 
ATOM   2315 C  C   . ASN B 1 122 ? 43.154  -4.134  45.797  1.00 74.06  ? 122 ASN A C   1 
ATOM   2316 O  O   . ASN B 1 122 ? 42.677  -3.048  45.440  1.00 73.61  ? 122 ASN A O   1 
ATOM   2317 C  CB  . ASN B 1 122 ? 45.414  -3.214  45.167  1.00 77.50  ? 122 ASN A CB  1 
ATOM   2318 C  CG  . ASN B 1 122 ? 46.909  -3.422  45.214  1.00 79.14  ? 122 ASN A CG  1 
ATOM   2319 O  OD1 . ASN B 1 122 ? 47.488  -4.044  44.323  1.00 75.00  ? 122 ASN A OD1 1 
ATOM   2320 N  ND2 . ASN B 1 122 ? 47.543  -2.927  46.276  1.00 82.62  ? 122 ASN A ND2 1 
ATOM   2321 N  N   . ASP B 1 123 ? 42.406  -5.186  46.122  1.00 73.08  ? 123 ASP A N   1 
ATOM   2322 C  CA  . ASP B 1 123 ? 41.017  -5.037  46.507  1.00 71.22  ? 123 ASP A CA  1 
ATOM   2323 C  C   . ASP B 1 123 ? 41.029  -4.796  48.010  1.00 66.27  ? 123 ASP A C   1 
ATOM   2324 O  O   . ASP B 1 123 ? 40.901  -5.743  48.797  1.00 60.05  ? 123 ASP A O   1 
ATOM   2325 C  CB  . ASP B 1 123 ? 40.189  -6.264  46.134  1.00 59.03  ? 123 ASP A CB  1 
ATOM   2326 C  CG  . ASP B 1 123 ? 38.708  -6.031  46.327  1.00 62.53  ? 123 ASP A CG  1 
ATOM   2327 O  OD1 . ASP B 1 123 ? 38.344  -4.970  46.891  1.00 60.97  ? 123 ASP A OD1 1 
ATOM   2328 O  OD2 . ASP B 1 123 ? 37.909  -6.904  45.922  1.00 67.70  ? 123 ASP A OD2 1 
ATOM   2329 N  N   . PRO B 1 124 ? 41.186  -3.541  48.441  1.00 68.48  ? 124 PRO A N   1 
ATOM   2330 C  CA  . PRO B 1 124 ? 41.417  -3.289  49.869  1.00 65.47  ? 124 PRO A CA  1 
ATOM   2331 C  C   . PRO B 1 124 ? 40.262  -3.711  50.739  1.00 69.51  ? 124 PRO A C   1 
ATOM   2332 O  O   . PRO B 1 124 ? 40.459  -3.988  51.930  1.00 75.01  ? 124 PRO A O   1 
ATOM   2333 C  CB  . PRO B 1 124 ? 41.624  -1.771  49.922  1.00 63.69  ? 124 PRO A CB  1 
ATOM   2334 C  CG  . PRO B 1 124 ? 40.788  -1.263  48.806  1.00 64.74  ? 124 PRO A CG  1 
ATOM   2335 C  CD  . PRO B 1 124 ? 40.901  -2.294  47.705  1.00 68.16  ? 124 PRO A CD  1 
ATOM   2336 N  N   . CYS B 1 125 ? 39.058  -3.774  50.188  1.00 71.88  ? 125 CYS A N   1 
ATOM   2337 C  CA  . CYS B 1 125 ? 37.893  -4.027  51.007  1.00 68.87  ? 125 CYS A CA  1 
ATOM   2338 C  C   . CYS B 1 125 ? 37.347  -5.438  50.825  1.00 62.23  ? 125 CYS A C   1 
ATOM   2339 O  O   . CYS B 1 125 ? 36.438  -5.841  51.558  1.00 60.82  ? 125 CYS A O   1 
ATOM   2340 C  CB  . CYS B 1 125 ? 36.859  -2.934  50.740  1.00 75.50  ? 125 CYS A CB  1 
ATOM   2341 S  SG  . CYS B 1 125 ? 37.256  -1.434  51.788  1.00 89.52  ? 125 CYS A SG  1 
ATOM   2342 N  N   . LEU B 1 126 ? 37.938  -6.226  49.925  1.00 58.75  ? 126 LEU A N   1 
ATOM   2343 C  CA  . LEU B 1 126 ? 37.828  -7.675  50.062  1.00 64.83  ? 126 LEU A CA  1 
ATOM   2344 C  C   . LEU B 1 126 ? 38.761  -8.187  51.163  1.00 65.69  ? 126 LEU A C   1 
ATOM   2345 O  O   . LEU B 1 126 ? 38.355  -9.006  51.996  1.00 58.16  ? 126 LEU A O   1 
ATOM   2346 C  CB  . LEU B 1 126 ? 38.122  -8.369  48.726  1.00 57.13  ? 126 LEU A CB  1 
ATOM   2347 C  CG  . LEU B 1 126 ? 38.065  -9.902  48.778  1.00 61.84  ? 126 LEU A CG  1 
ATOM   2348 C  CD1 . LEU B 1 126 ? 36.739  -10.371 49.373  1.00 62.34  ? 126 LEU A CD1 1 
ATOM   2349 C  CD2 . LEU B 1 126 ? 38.322  -10.583 47.423  1.00 57.58  ? 126 LEU A CD2 1 
ATOM   2350 N  N   . THR B 1 127 ? 40.014  -7.699  51.196  1.00 69.51  ? 127 THR A N   1 
ATOM   2351 C  CA  . THR B 1 127 ? 40.939  -8.099  52.256  1.00 68.71  ? 127 THR A CA  1 
ATOM   2352 C  C   . THR B 1 127 ? 40.425  -7.696  53.622  1.00 68.89  ? 127 THR A C   1 
ATOM   2353 O  O   . THR B 1 127 ? 40.771  -8.341  54.615  1.00 70.56  ? 127 THR A O   1 
ATOM   2354 C  CB  . THR B 1 127 ? 42.340  -7.489  52.087  1.00 61.54  ? 127 THR A CB  1 
ATOM   2355 O  OG1 . THR B 1 127 ? 42.276  -6.078  52.308  1.00 69.65  ? 127 THR A OG1 1 
ATOM   2356 C  CG2 . THR B 1 127 ? 42.929  -7.747  50.723  1.00 59.99  ? 127 THR A CG2 1 
ATOM   2357 N  N   . LYS B 1 128 ? 39.618  -6.642  53.700  1.00 59.69  ? 128 LYS A N   1 
ATOM   2358 C  CA  . LYS B 1 128 ? 39.059  -6.281  54.989  1.00 65.35  ? 128 LYS A CA  1 
ATOM   2359 C  C   . LYS B 1 128 ? 37.997  -7.290  55.423  1.00 75.01  ? 128 LYS A C   1 
ATOM   2360 O  O   . LYS B 1 128 ? 38.103  -7.868  56.512  1.00 76.08  ? 128 LYS A O   1 
ATOM   2361 C  CB  . LYS B 1 128 ? 38.496  -4.864  54.939  1.00 67.55  ? 128 LYS A CB  1 
ATOM   2362 C  CG  . LYS B 1 128 ? 38.083  -4.357  56.296  1.00 85.27  ? 128 LYS A CG  1 
ATOM   2363 C  CD  . LYS B 1 128 ? 36.615  -4.081  56.331  1.00 85.12  ? 128 LYS A CD  1 
ATOM   2364 C  CE  . LYS B 1 128 ? 36.225  -3.371  57.606  1.00 85.55  ? 128 LYS A CE  1 
ATOM   2365 N  NZ  . LYS B 1 128 ? 34.740  -3.409  57.743  1.00 87.00  ? 128 LYS A NZ  1 
ATOM   2366 N  N   . LEU B 1 129 ? 36.975  -7.523  54.578  1.00 71.87  ? 129 LEU A N   1 
ATOM   2367 C  CA  . LEU B 1 129 ? 35.972  -8.558  54.860  1.00 71.32  ? 129 LEU A CA  1 
ATOM   2368 C  C   . LEU B 1 129 ? 36.627  -9.890  55.188  1.00 71.79  ? 129 LEU A C   1 
ATOM   2369 O  O   . LEU B 1 129 ? 36.197  -10.595 56.108  1.00 70.91  ? 129 LEU A O   1 
ATOM   2370 C  CB  . LEU B 1 129 ? 35.017  -8.751  53.674  1.00 66.01  ? 129 LEU A CB  1 
ATOM   2371 C  CG  . LEU B 1 129 ? 34.024  -9.924  53.815  1.00 58.43  ? 129 LEU A CG  1 
ATOM   2372 C  CD1 . LEU B 1 129 ? 32.677  -9.464  54.347  1.00 59.39  ? 129 LEU A CD1 1 
ATOM   2373 C  CD2 . LEU B 1 129 ? 33.847  -10.741 52.533  1.00 58.03  ? 129 LEU A CD2 1 
ATOM   2374 N  N   . LEU B 1 130 ? 37.670  -10.247 54.439  1.00 67.30  ? 130 LEU A N   1 
ATOM   2375 C  CA  . LEU B 1 130 ? 38.366  -11.506 54.673  1.00 66.60  ? 130 LEU A CA  1 
ATOM   2376 C  C   . LEU B 1 130 ? 39.079  -11.513 56.017  1.00 74.89  ? 130 LEU A C   1 
ATOM   2377 O  O   . LEU B 1 130 ? 38.945  -12.467 56.790  1.00 81.27  ? 130 LEU A O   1 
ATOM   2378 C  CB  . LEU B 1 130 ? 39.361  -11.762 53.551  1.00 61.46  ? 130 LEU A CB  1 
ATOM   2379 C  CG  . LEU B 1 130 ? 38.640  -12.179 52.291  1.00 67.07  ? 130 LEU A CG  1 
ATOM   2380 C  CD1 . LEU B 1 130 ? 39.633  -12.266 51.160  1.00 67.83  ? 130 LEU A CD1 1 
ATOM   2381 C  CD2 . LEU B 1 130 ? 37.942  -13.497 52.569  1.00 62.60  ? 130 LEU A CD2 1 
ATOM   2382 N  N   . GLU B 1 131 ? 39.857  -10.469 56.309  1.00 77.77  ? 131 GLU A N   1 
ATOM   2383 C  CA  . GLU B 1 131 ? 40.656  -10.484 57.529  1.00 84.15  ? 131 GLU A CA  1 
ATOM   2384 C  C   . GLU B 1 131 ? 39.825  -10.254 58.786  1.00 83.76  ? 131 GLU A C   1 
ATOM   2385 O  O   . GLU B 1 131 ? 40.333  -10.494 59.889  1.00 83.53  ? 131 GLU A O   1 
ATOM   2386 C  CB  . GLU B 1 131 ? 41.808  -9.468  57.431  1.00 83.99  ? 131 GLU A CB  1 
ATOM   2387 C  CG  . GLU B 1 131 ? 41.482  -8.014  57.758  1.00 85.90  ? 131 GLU A CG  1 
ATOM   2388 C  CD  . GLU B 1 131 ? 42.671  -7.115  57.468  1.00 89.34  ? 131 GLU A CD  1 
ATOM   2389 O  OE1 . GLU B 1 131 ? 42.649  -5.919  57.858  1.00 93.45  ? 131 GLU A OE1 1 
ATOM   2390 O  OE2 . GLU B 1 131 ? 43.635  -7.633  56.851  1.00 82.52  ? 131 GLU A OE2 1 
ATOM   2391 N  N   . ASP B 1 132 ? 38.564  -9.825  58.647  1.00 79.34  ? 132 ASP A N   1 
ATOM   2392 C  CA  . ASP B 1 132 ? 37.629  -9.898  59.768  1.00 84.55  ? 132 ASP A CA  1 
ATOM   2393 C  C   . ASP B 1 132 ? 37.259  -11.349 60.074  1.00 88.85  ? 132 ASP A C   1 
ATOM   2394 O  O   . ASP B 1 132 ? 37.445  -11.822 61.200  1.00 89.00  ? 132 ASP A O   1 
ATOM   2395 C  CB  . ASP B 1 132 ? 36.369  -9.076  59.478  1.00 83.72  ? 132 ASP A CB  1 
ATOM   2396 C  CG  . ASP B 1 132 ? 36.629  -7.580  59.469  1.00 85.22  ? 132 ASP A CG  1 
ATOM   2397 O  OD1 . ASP B 1 132 ? 35.704  -6.825  59.089  1.00 83.11  ? 132 ASP A OD1 1 
ATOM   2398 O  OD2 . ASP B 1 132 ? 37.754  -7.159  59.826  1.00 83.37  ? 132 ASP A OD2 1 
ATOM   2399 N  N   . GLU B 1 133 ? 36.755  -12.080 59.067  1.00 86.43  ? 133 GLU A N   1 
ATOM   2400 C  CA  . GLU B 1 133 ? 36.221  -13.426 59.294  1.00 84.22  ? 133 GLU A CA  1 
ATOM   2401 C  C   . GLU B 1 133 ? 37.312  -14.417 59.700  1.00 83.96  ? 133 GLU A C   1 
ATOM   2402 O  O   . GLU B 1 133 ? 37.079  -15.272 60.562  1.00 82.57  ? 133 GLU A O   1 
ATOM   2403 C  CB  . GLU B 1 133 ? 35.481  -13.927 58.046  1.00 77.28  ? 133 GLU A CB  1 
ATOM   2404 C  CG  . GLU B 1 133 ? 34.303  -13.030 57.594  1.00 90.56  ? 133 GLU A CG  1 
ATOM   2405 C  CD  . GLU B 1 133 ? 32.964  -13.771 57.477  1.00 96.58  ? 133 GLU A CD  1 
ATOM   2406 O  OE1 . GLU B 1 133 ? 32.861  -14.739 56.687  1.00 95.80  ? 133 GLU A OE1 1 
ATOM   2407 O  OE2 . GLU B 1 133 ? 32.000  -13.370 58.164  1.00 90.17  ? 133 GLU A OE2 1 
ATOM   2408 N  N   . TYR B 1 134 ? 38.507  -14.324 59.099  1.00 84.86  ? 134 TYR A N   1 
ATOM   2409 C  CA  . TYR B 1 134 ? 39.558  -15.311 59.370  1.00 90.72  ? 134 TYR A CA  1 
ATOM   2410 C  C   . TYR B 1 134 ? 40.163  -15.120 60.757  1.00 92.40  ? 134 TYR A C   1 
ATOM   2411 O  O   . TYR B 1 134 ? 40.397  -16.096 61.483  1.00 87.97  ? 134 TYR A O   1 
ATOM   2412 C  CB  . TYR B 1 134 ? 40.660  -15.244 58.304  1.00 84.79  ? 134 TYR A CB  1 
ATOM   2413 C  CG  . TYR B 1 134 ? 41.939  -16.003 58.665  1.00 85.66  ? 134 TYR A CG  1 
ATOM   2414 C  CD1 . TYR B 1 134 ? 42.005  -17.394 58.574  1.00 85.47  ? 134 TYR A CD1 1 
ATOM   2415 C  CD2 . TYR B 1 134 ? 43.078  -15.329 59.088  1.00 85.86  ? 134 TYR A CD2 1 
ATOM   2416 C  CE1 . TYR B 1 134 ? 43.173  -18.091 58.899  1.00 82.09  ? 134 TYR A CE1 1 
ATOM   2417 C  CE2 . TYR B 1 134 ? 44.247  -16.018 59.413  1.00 89.22  ? 134 TYR A CE2 1 
ATOM   2418 C  CZ  . TYR B 1 134 ? 44.289  -17.397 59.315  1.00 81.09  ? 134 TYR A CZ  1 
ATOM   2419 O  OH  . TYR B 1 134 ? 45.445  -18.073 59.639  1.00 72.64  ? 134 TYR A OH  1 
ATOM   2420 N  N   . CYS B 1 135 ? 40.446  -13.874 61.137  1.00 94.60  ? 135 CYS A N   1 
ATOM   2421 C  CA  . CYS B 1 135 ? 40.993  -13.610 62.458  1.00 91.17  ? 135 CYS A CA  1 
ATOM   2422 C  C   . CYS B 1 135 ? 39.917  -13.370 63.508  1.00 90.17  ? 135 CYS A C   1 
ATOM   2423 O  O   . CYS B 1 135 ? 40.251  -13.215 64.688  1.00 91.70  ? 135 CYS A O   1 
ATOM   2424 C  CB  . CYS B 1 135 ? 41.984  -12.447 62.404  1.00 83.09  ? 135 CYS A CB  1 
ATOM   2425 S  SG  . CYS B 1 135 ? 43.742  -13.075 62.255  1.00 101.98 ? 135 CYS A SG  1 
ATOM   2426 N  N   . GLU B 1 136 ? 38.639  -13.368 63.123  1.00 86.61  ? 136 GLU A N   1 
ATOM   2427 C  CA  . GLU B 1 136 ? 37.609  -13.606 64.123  1.00 91.08  ? 136 GLU A CA  1 
ATOM   2428 C  C   . GLU B 1 136 ? 37.418  -15.100 64.353  1.00 91.82  ? 136 GLU A C   1 
ATOM   2429 O  O   . GLU B 1 136 ? 37.005  -15.513 65.443  1.00 88.95  ? 136 GLU A O   1 
ATOM   2430 C  CB  . GLU B 1 136 ? 36.289  -12.953 63.704  1.00 93.49  ? 136 GLU A CB  1 
ATOM   2431 C  CG  . GLU B 1 136 ? 36.000  -11.595 64.351  1.00 94.80  ? 136 GLU A CG  1 
ATOM   2432 C  CD  . GLU B 1 136 ? 36.524  -11.495 65.783  1.00 104.17 ? 136 GLU A CD  1 
ATOM   2433 O  OE1 . GLU B 1 136 ? 37.679  -11.044 65.972  1.00 99.57  ? 136 GLU A OE1 1 
ATOM   2434 O  OE2 . GLU B 1 136 ? 35.787  -11.882 66.718  1.00 109.92 ? 136 GLU A OE2 1 
ATOM   2435 N  N   . GLU B 1 137 ? 37.740  -15.915 63.341  1.00 93.59  ? 137 GLU A N   1 
ATOM   2436 C  CA  . GLU B 1 137 ? 37.614  -17.364 63.440  1.00 87.88  ? 137 GLU A CA  1 
ATOM   2437 C  C   . GLU B 1 137 ? 38.725  -17.976 64.277  1.00 86.23  ? 137 GLU A C   1 
ATOM   2438 O  O   . GLU B 1 137 ? 38.495  -18.990 64.948  1.00 77.51  ? 137 GLU A O   1 
ATOM   2439 C  CB  . GLU B 1 137 ? 37.603  -17.993 62.040  1.00 82.57  ? 137 GLU A CB  1 
ATOM   2440 C  CG  . GLU B 1 137 ? 36.870  -19.342 61.956  1.00 83.52  ? 137 GLU A CG  1 
ATOM   2441 C  CD  . GLU B 1 137 ? 35.342  -19.199 62.025  1.00 86.85  ? 137 GLU A CD  1 
ATOM   2442 O  OE1 . GLU B 1 137 ? 34.836  -18.059 61.903  1.00 87.47  ? 137 GLU A OE1 1 
ATOM   2443 O  OE2 . GLU B 1 137 ? 34.643  -20.227 62.203  1.00 82.97  ? 137 GLU A OE2 1 
ATOM   2444 N  N   . GLN B 1 138 ? 39.924  -17.382 64.253  1.00 91.94  ? 138 GLN A N   1 
ATOM   2445 C  CA  . GLN B 1 138 ? 41.035  -17.929 65.024  1.00 90.43  ? 138 GLN A CA  1 
ATOM   2446 C  C   . GLN B 1 138 ? 40.706  -17.928 66.510  1.00 89.30  ? 138 GLN A C   1 
ATOM   2447 O  O   . GLN B 1 138 ? 40.463  -18.983 67.095  1.00 87.37  ? 138 GLN A O   1 
ATOM   2448 C  CB  . GLN B 1 138 ? 42.333  -17.165 64.729  1.00 84.25  ? 138 GLN A CB  1 
ATOM   2449 C  CG  . GLN B 1 138 ? 42.791  -17.251 63.269  1.00 89.23  ? 138 GLN A CG  1 
ATOM   2450 C  CD  . GLN B 1 138 ? 42.900  -18.690 62.752  1.00 89.96  ? 138 GLN A CD  1 
ATOM   2451 O  OE1 . GLN B 1 138 ? 41.945  -19.238 62.195  1.00 92.30  ? 138 GLN A OE1 1 
ATOM   2452 N  NE2 . GLN B 1 138 ? 44.064  -19.304 62.944  1.00 87.16  ? 138 GLN A NE2 1 
ATOM   2453 N  N   . CYS B 1 139 ? 40.608  -16.747 67.116  1.00 91.78  ? 139 CYS A N   1 
ATOM   2454 C  CA  . CYS B 1 139 ? 40.367  -16.600 68.549  1.00 87.75  ? 139 CYS A CA  1 
ATOM   2455 C  C   . CYS B 1 139 ? 38.995  -17.061 69.008  1.00 83.14  ? 139 CYS A C   1 
ATOM   2456 O  O   . CYS B 1 139 ? 38.714  -17.002 70.209  1.00 81.23  ? 139 CYS A O   1 
ATOM   2457 C  CB  . CYS B 1 139 ? 40.548  -15.147 68.939  1.00 86.98  ? 139 CYS A CB  1 
ATOM   2458 S  SG  . CYS B 1 139 ? 42.281  -14.780 68.905  1.00 105.54 ? 139 CYS A SG  1 
ATOM   2459 N  N   . ASP B 1 140 ? 38.122  -17.482 68.106  1.00 82.33  ? 140 ASP A N   1 
ATOM   2460 C  CA  . ASP B 1 140 ? 36.826  -17.945 68.570  1.00 81.04  ? 140 ASP A CA  1 
ATOM   2461 C  C   . ASP B 1 140 ? 36.631  -19.426 68.278  1.00 75.11  ? 140 ASP A C   1 
ATOM   2462 O  O   . ASP B 1 140 ? 36.875  -20.267 69.150  1.00 73.84  ? 140 ASP A O   1 
ATOM   2463 C  CB  . ASP B 1 140 ? 35.702  -17.114 67.947  1.00 79.73  ? 140 ASP A CB  1 
ATOM   2464 C  CG  . ASP B 1 140 ? 34.445  -17.085 68.817  1.00 88.50  ? 140 ASP A CG  1 
ATOM   2465 O  OD1 . ASP B 1 140 ? 33.383  -16.651 68.316  1.00 88.41  ? 140 ASP A OD1 1 
ATOM   2466 O  OD2 . ASP B 1 140 ? 34.512  -17.500 70.001  1.00 89.61  ? 140 ASP A OD2 1 
ATOM   2467 N  N   . SER B 1 141 ? 36.228  -19.755 67.049  1.00 73.24  ? 141 SER A N   1 
ATOM   2468 C  CA  A SER B 1 141 ? 35.859  -21.129 66.728  0.44 68.46  ? 141 SER A CA  1 
ATOM   2469 C  CA  B SER B 1 141 ? 35.857  -21.131 66.734  0.56 68.64  ? 141 SER A CA  1 
ATOM   2470 C  C   . SER B 1 141 ? 37.051  -22.081 66.800  1.00 62.01  ? 141 SER A C   1 
ATOM   2471 O  O   . SER B 1 141 ? 36.918  -23.217 67.266  1.00 55.60  ? 141 SER A O   1 
ATOM   2472 C  CB  A SER B 1 141 ? 35.215  -21.180 65.344  0.44 69.08  ? 141 SER A CB  1 
ATOM   2473 C  CB  B SER B 1 141 ? 35.188  -21.192 65.360  0.56 67.93  ? 141 SER A CB  1 
ATOM   2474 O  OG  A SER B 1 141 ? 35.386  -22.455 64.758  0.44 62.04  ? 141 SER A OG  1 
ATOM   2475 O  OG  B SER B 1 141 ? 33.804  -20.883 65.449  0.56 67.36  ? 141 SER A OG  1 
ATOM   2476 N  N   . ILE B 1 142 ? 38.233  -21.652 66.342  1.00 67.63  ? 142 ILE A N   1 
ATOM   2477 C  CA  . ILE B 1 142 ? 39.363  -22.588 66.321  1.00 61.81  ? 142 ILE A CA  1 
ATOM   2478 C  C   . ILE B 1 142 ? 39.863  -22.893 67.733  1.00 61.54  ? 142 ILE A C   1 
ATOM   2479 O  O   . ILE B 1 142 ? 40.372  -23.990 68.000  1.00 56.92  ? 142 ILE A O   1 
ATOM   2480 C  CB  . ILE B 1 142 ? 40.491  -22.056 65.413  1.00 68.66  ? 142 ILE A CB  1 
ATOM   2481 C  CG1 . ILE B 1 142 ? 40.014  -21.968 63.962  1.00 73.57  ? 142 ILE A CG1 1 
ATOM   2482 C  CG2 . ILE B 1 142 ? 41.710  -22.956 65.470  1.00 58.43  ? 142 ILE A CG2 1 
ATOM   2483 C  CD1 . ILE B 1 142 ? 40.238  -23.242 63.186  1.00 66.98  ? 142 ILE A CD1 1 
ATOM   2484 N  N   . LYS B 1 143 ? 39.684  -21.964 68.667  1.00 66.49  ? 143 LYS A N   1 
ATOM   2485 C  CA  . LYS B 1 143 ? 40.222  -22.139 70.008  1.00 61.74  ? 143 LYS A CA  1 
ATOM   2486 C  C   . LYS B 1 143 ? 39.254  -22.834 70.914  1.00 57.57  ? 143 LYS A C   1 
ATOM   2487 O  O   . LYS B 1 143 ? 39.646  -23.641 71.771  1.00 55.80  ? 143 LYS A O   1 
ATOM   2488 C  CB  . LYS B 1 143 ? 40.568  -20.786 70.591  1.00 69.07  ? 143 LYS A CB  1 
ATOM   2489 C  CG  . LYS B 1 143 ? 41.205  -20.100 69.530  1.00 82.37  ? 143 LYS A CG  1 
ATOM   2490 C  CD  . LYS B 1 143 ? 42.562  -20.603 69.781  1.00 84.66  ? 143 LYS A CD  1 
ATOM   2491 C  CE  . LYS B 1 143 ? 43.603  -19.861 69.130  1.00 81.01  ? 143 LYS A CE  1 
ATOM   2492 N  NZ  . LYS B 1 143 ? 44.944  -20.493 69.551  1.00 80.97  ? 143 LYS A NZ  1 
ATOM   2493 N  N   . LYS B 1 144 ? 37.996  -22.463 70.779  1.00 47.88  ? 144 LYS A N   1 
ATOM   2494 C  CA  . LYS B 1 144 ? 37.010  -23.112 71.594  1.00 50.25  ? 144 LYS A CA  1 
ATOM   2495 C  C   . LYS B 1 144 ? 37.041  -24.608 71.313  1.00 53.52  ? 144 LYS A C   1 
ATOM   2496 O  O   . LYS B 1 144 ? 37.017  -25.417 72.248  1.00 49.33  ? 144 LYS A O   1 
ATOM   2497 C  CB  . LYS B 1 144 ? 35.654  -22.471 71.341  1.00 54.18  ? 144 LYS A CB  1 
ATOM   2498 C  CG  . LYS B 1 144 ? 34.569  -23.069 72.179  1.00 63.81  ? 144 LYS A CG  1 
ATOM   2499 C  CD  . LYS B 1 144 ? 33.278  -23.222 71.413  1.00 58.63  ? 144 LYS A CD  1 
ATOM   2500 C  CE  . LYS B 1 144 ? 33.008  -22.017 70.511  1.00 70.22  ? 144 LYS A CE  1 
ATOM   2501 N  NZ  . LYS B 1 144 ? 31.675  -22.080 69.818  1.00 64.42  ? 144 LYS A NZ  1 
ATOM   2502 N  N   . ILE B 1 145 ? 37.232  -24.989 70.042  1.00 46.45  ? 145 ILE A N   1 
ATOM   2503 C  CA  . ILE B 1 145 ? 37.369  -26.404 69.717  1.00 49.40  ? 145 ILE A CA  1 
ATOM   2504 C  C   . ILE B 1 145 ? 38.668  -26.961 70.292  1.00 44.34  ? 145 ILE A C   1 
ATOM   2505 O  O   . ILE B 1 145 ? 38.694  -28.070 70.846  1.00 38.34  ? 145 ILE A O   1 
ATOM   2506 C  CB  . ILE B 1 145 ? 37.282  -26.626 68.196  1.00 45.69  ? 145 ILE A CB  1 
ATOM   2507 C  CG1 . ILE B 1 145 ? 35.856  -26.383 67.694  1.00 40.02  ? 145 ILE A CG1 1 
ATOM   2508 C  CG2 . ILE B 1 145 ? 37.717  -28.054 67.841  1.00 37.87  ? 145 ILE A CG2 1 
ATOM   2509 C  CD1 . ILE B 1 145 ? 35.753  -26.496 66.164  1.00 38.60  ? 145 ILE A CD1 1 
ATOM   2510 N  N   . GLY B 1 146 ? 39.764  -26.210 70.159  1.00 42.46  ? 146 GLY A N   1 
ATOM   2511 C  CA  . GLY B 1 146 ? 41.024  -26.661 70.718  1.00 35.81  ? 146 GLY A CA  1 
ATOM   2512 C  C   . GLY B 1 146 ? 40.920  -26.884 72.215  1.00 48.05  ? 146 GLY A C   1 
ATOM   2513 O  O   . GLY B 1 146 ? 41.423  -27.882 72.747  1.00 43.62  ? 146 GLY A O   1 
ATOM   2514 N  N   . CYS B 1 147 ? 40.217  -25.983 72.905  1.00 46.06  ? 147 CYS A N   1 
ATOM   2515 C  CA  . CYS B 1 147 ? 40.020  -26.126 74.343  1.00 45.64  ? 147 CYS A CA  1 
ATOM   2516 C  C   . CYS B 1 147 ? 39.056  -27.254 74.690  1.00 42.22  ? 147 CYS A C   1 
ATOM   2517 O  O   . CYS B 1 147 ? 39.265  -27.972 75.679  1.00 38.10  ? 147 CYS A O   1 
ATOM   2518 C  CB  . CYS B 1 147 ? 39.524  -24.809 74.920  1.00 51.31  ? 147 CYS A CB  1 
ATOM   2519 S  SG  . CYS B 1 147 ? 39.797  -24.713 76.651  1.00 82.56  ? 147 CYS A SG  1 
ATOM   2520 N  N   . MET B 1 148 ? 37.987  -27.417 73.908  1.00 43.97  ? 148 MET A N   1 
ATOM   2521 C  CA  . MET B 1 148 ? 37.101  -28.557 74.115  1.00 44.67  ? 148 MET A CA  1 
ATOM   2522 C  C   . MET B 1 148 ? 37.894  -29.858 74.079  1.00 43.18  ? 148 MET A C   1 
ATOM   2523 O  O   . MET B 1 148 ? 37.692  -30.751 74.914  1.00 37.26  ? 148 MET A O   1 
ATOM   2524 C  CB  . MET B 1 148 ? 35.980  -28.558 73.067  1.00 44.84  ? 148 MET A CB  1 
ATOM   2525 C  CG  . MET B 1 148 ? 34.926  -27.457 73.255  1.00 45.82  ? 148 MET A CG  1 
ATOM   2526 S  SD  . MET B 1 148 ? 33.894  -27.134 71.792  1.00 47.54  ? 148 MET A SD  1 
ATOM   2527 C  CE  . MET B 1 148 ? 32.930  -28.636 71.780  1.00 41.02  ? 148 MET A CE  1 
ATOM   2528 N  N   . ILE B 1 149 ? 38.840  -29.957 73.150  1.00 39.12  ? 149 ILE A N   1 
ATOM   2529 C  CA  . ILE B 1 149 ? 39.621  -31.178 73.031  1.00 41.12  ? 149 ILE A CA  1 
ATOM   2530 C  C   . ILE B 1 149 ? 40.495  -31.368 74.256  1.00 39.69  ? 149 ILE A C   1 
ATOM   2531 O  O   . ILE B 1 149 ? 40.562  -32.472 74.818  1.00 38.09  ? 149 ILE A O   1 
ATOM   2532 C  CB  . ILE B 1 149 ? 40.458  -31.151 71.746  1.00 40.99  ? 149 ILE A CB  1 
ATOM   2533 C  CG1 . ILE B 1 149 ? 39.543  -31.307 70.538  1.00 35.62  ? 149 ILE A CG1 1 
ATOM   2534 C  CG2 . ILE B 1 149 ? 41.558  -32.188 71.826  1.00 33.32  ? 149 ILE A CG2 1 
ATOM   2535 C  CD1 . ILE B 1 149 ? 40.268  -31.161 69.220  1.00 38.87  ? 149 ILE A CD1 1 
ATOM   2536 N  N   . THR B 1 150 ? 41.179  -30.296 74.686  1.00 39.44  ? 150 THR A N   1 
ATOM   2537 C  CA  . THR B 1 150 ? 41.966  -30.350 75.921  1.00 37.19  ? 150 THR A CA  1 
ATOM   2538 C  C   . THR B 1 150 ? 41.117  -30.802 77.099  1.00 35.75  ? 150 THR A C   1 
ATOM   2539 O  O   . THR B 1 150 ? 41.546  -31.629 77.908  1.00 41.53  ? 150 THR A O   1 
ATOM   2540 C  CB  . THR B 1 150 ? 42.573  -28.985 76.240  1.00 41.00  ? 150 THR A CB  1 
ATOM   2541 O  OG1 . THR B 1 150 ? 43.495  -28.614 75.219  1.00 42.16  ? 150 THR A OG1 1 
ATOM   2542 C  CG2 . THR B 1 150 ? 43.310  -29.025 77.579  1.00 36.93  ? 150 THR A CG2 1 
ATOM   2543 N  N   . LYS B 1 151 ? 39.915  -30.241 77.229  1.00 39.83  ? 151 LYS A N   1 
ATOM   2544 C  CA  . LYS B 1 151 ? 39.071  -30.587 78.365  1.00 40.38  ? 151 LYS A CA  1 
ATOM   2545 C  C   . LYS B 1 151 ? 38.591  -32.029 78.273  1.00 44.90  ? 151 LYS A C   1 
ATOM   2546 O  O   . LYS B 1 151 ? 38.615  -32.764 79.272  1.00 41.45  ? 151 LYS A O   1 
ATOM   2547 C  CB  . LYS B 1 151 ? 37.886  -29.627 78.462  1.00 37.79  ? 151 LYS A CB  1 
ATOM   2548 C  CG  . LYS B 1 151 ? 36.877  -30.022 79.546  1.00 50.93  ? 151 LYS A CG  1 
ATOM   2549 C  CD  . LYS B 1 151 ? 35.685  -29.065 79.602  1.00 50.24  ? 151 LYS A CD  1 
ATOM   2550 C  CE  . LYS B 1 151 ? 34.682  -29.497 80.657  1.00 47.85  ? 151 LYS A CE  1 
ATOM   2551 N  NZ  . LYS B 1 151 ? 33.464  -28.655 80.637  1.00 47.84  ? 151 LYS A NZ  1 
ATOM   2552 N  N   . LEU B 1 152 ? 38.165  -32.465 77.084  1.00 39.84  ? 152 LEU A N   1 
ATOM   2553 C  CA  . LEU B 1 152 ? 37.699  -33.840 76.971  1.00 39.22  ? 152 LEU A CA  1 
ATOM   2554 C  C   . LEU B 1 152 ? 38.821  -34.818 77.294  1.00 43.30  ? 152 LEU A C   1 
ATOM   2555 O  O   . LEU B 1 152 ? 38.583  -35.853 77.919  1.00 43.37  ? 152 LEU A O   1 
ATOM   2556 C  CB  . LEU B 1 152 ? 37.121  -34.076 75.577  1.00 41.14  ? 152 LEU A CB  1 
ATOM   2557 C  CG  . LEU B 1 152 ? 36.341  -35.357 75.281  1.00 44.84  ? 152 LEU A CG  1 
ATOM   2558 C  CD1 . LEU B 1 152 ? 35.322  -35.632 76.356  1.00 41.95  ? 152 LEU A CD1 1 
ATOM   2559 C  CD2 . LEU B 1 152 ? 35.637  -35.211 73.945  1.00 43.77  ? 152 LEU A CD2 1 
ATOM   2560 N  N   . LYS B 1 153 ? 40.061  -34.475 76.941  1.00 43.16  ? 153 LYS A N   1 
ATOM   2561 C  CA  . LYS B 1 153 ? 41.186  -35.344 77.275  1.00 43.38  ? 153 LYS A CA  1 
ATOM   2562 C  C   . LYS B 1 153 ? 41.465  -35.375 78.785  1.00 46.25  ? 153 LYS A C   1 
ATOM   2563 O  O   . LYS B 1 153 ? 41.835  -36.423 79.335  1.00 45.82  ? 153 LYS A O   1 
ATOM   2564 C  CB  . LYS B 1 153 ? 42.419  -34.889 76.511  1.00 38.45  ? 153 LYS A CB  1 
ATOM   2565 C  CG  . LYS B 1 153 ? 42.387  -35.170 75.024  1.00 40.76  ? 153 LYS A CG  1 
ATOM   2566 C  CD  . LYS B 1 153 ? 43.752  -34.863 74.433  1.00 41.00  ? 153 LYS A CD  1 
ATOM   2567 C  CE  . LYS B 1 153 ? 43.809  -35.159 72.950  1.00 47.92  ? 153 LYS A CE  1 
ATOM   2568 N  NZ  . LYS B 1 153 ? 45.076  -34.599 72.365  1.00 48.69  ? 153 LYS A NZ  1 
ATOM   2569 N  N   . ARG B 1 154 ? 41.308  -34.239 79.468  1.00 40.50  ? 154 ARG A N   1 
ATOM   2570 C  CA  . ARG B 1 154 ? 41.485  -34.208 80.916  1.00 40.03  ? 154 ARG A CA  1 
ATOM   2571 C  C   . ARG B 1 154 ? 40.353  -34.940 81.634  1.00 45.50  ? 154 ARG A C   1 
ATOM   2572 O  O   . ARG B 1 154 ? 40.599  -35.803 82.483  1.00 41.86  ? 154 ARG A O   1 
ATOM   2573 C  CB  . ARG B 1 154 ? 41.566  -32.758 81.404  1.00 47.36  ? 154 ARG A CB  1 
ATOM   2574 C  CG  . ARG B 1 154 ? 41.279  -32.605 82.898  1.00 51.20  ? 154 ARG A CG  1 
ATOM   2575 C  CD  . ARG B 1 154 ? 41.260  -31.150 83.329  1.00 50.53  ? 154 ARG A CD  1 
ATOM   2576 N  NE  . ARG B 1 154 ? 42.481  -30.478 82.902  1.00 50.93  ? 154 ARG A NE  1 
ATOM   2577 C  CZ  . ARG B 1 154 ? 42.514  -29.510 81.994  1.00 52.48  ? 154 ARG A CZ  1 
ATOM   2578 N  NH1 . ARG B 1 154 ? 41.381  -29.080 81.412  1.00 47.70  ? 154 ARG A NH1 1 
ATOM   2579 N  NH2 . ARG B 1 154 ? 43.683  -28.971 81.670  1.00 44.98  ? 154 ARG A NH2 1 
ATOM   2580 N  N   . CYS B 1 155 ? 39.099  -34.595 81.322  1.00 41.16  ? 155 CYS A N   1 
ATOM   2581 C  CA  . CYS B 1 155 ? 37.958  -35.257 81.950  1.00 47.52  ? 155 CYS A CA  1 
ATOM   2582 C  C   . CYS B 1 155 ? 37.982  -36.770 81.733  1.00 51.43  ? 155 CYS A C   1 
ATOM   2583 O  O   . CYS B 1 155 ? 37.256  -37.492 82.430  1.00 42.12  ? 155 CYS A O   1 
ATOM   2584 C  CB  . CYS B 1 155 ? 36.648  -34.634 81.417  1.00 40.45  ? 155 CYS A CB  1 
ATOM   2585 S  SG  . CYS B 1 155 ? 36.304  -32.935 82.069  1.00 71.27  ? 155 CYS A SG  1 
ATOM   2586 N  N   . GLY B 1 156 ? 38.884  -37.259 80.865  1.00 63.68  ? 156 GLY A N   1 
ATOM   2587 C  CA  . GLY B 1 156 ? 38.892  -38.618 80.368  1.00 52.33  ? 156 GLY A CA  1 
ATOM   2588 C  C   . GLY B 1 156 ? 37.994  -38.627 79.159  1.00 54.40  ? 156 GLY A C   1 
ATOM   2589 O  O   . GLY B 1 156 ? 36.838  -38.202 79.245  1.00 55.51  ? 156 GLY A O   1 
ATOM   2590 N  N   . PRO B 1 157 ? 38.510  -39.037 77.991  1.00 57.48  ? 157 PRO A N   1 
ATOM   2591 C  CA  . PRO B 1 157 ? 37.734  -38.873 76.743  1.00 48.36  ? 157 PRO A CA  1 
ATOM   2592 C  C   . PRO B 1 157 ? 36.625  -39.896 76.573  1.00 54.95  ? 157 PRO A C   1 
ATOM   2593 O  O   . PRO B 1 157 ? 35.830  -39.770 75.630  1.00 55.99  ? 157 PRO A O   1 
ATOM   2594 C  CB  . PRO B 1 157 ? 38.789  -39.035 75.627  1.00 48.65  ? 157 PRO A CB  1 
ATOM   2595 C  CG  . PRO B 1 157 ? 40.141  -39.188 76.340  1.00 56.79  ? 157 PRO A CG  1 
ATOM   2596 C  CD  . PRO B 1 157 ? 39.828  -39.644 77.750  1.00 56.23  ? 157 PRO A CD  1 
ATOM   2597 N  N   . THR B 1 158 ? 36.546  -40.899 77.444  1.00 53.14  ? 158 THR A N   1 
ATOM   2598 C  CA  . THR B 1 158 ? 35.541  -41.940 77.332  1.00 53.56  ? 158 THR A CA  1 
ATOM   2599 C  C   . THR B 1 158 ? 34.794  -42.088 78.655  1.00 56.33  ? 158 THR A C   1 
ATOM   2600 O  O   . THR B 1 158 ? 35.144  -41.493 79.686  1.00 52.30  ? 158 THR A O   1 
ATOM   2601 C  CB  . THR B 1 158 ? 36.174  -43.276 76.921  1.00 53.63  ? 158 THR A CB  1 
ATOM   2602 O  OG1 . THR B 1 158 ? 37.415  -43.438 77.616  1.00 64.04  ? 158 THR A OG1 1 
ATOM   2603 C  CG2 . THR B 1 158 ? 36.454  -43.291 75.414  1.00 50.86  ? 158 THR A CG2 1 
ATOM   2604 N  N   . GLY B 1 159 ? 33.722  -42.868 78.593  1.00 53.02  ? 159 GLY A N   1 
ATOM   2605 C  CA  . GLY B 1 159 ? 32.988  -43.213 79.791  1.00 47.16  ? 159 GLY A CA  1 
ATOM   2606 C  C   . GLY B 1 159 ? 32.419  -42.000 80.491  1.00 47.87  ? 159 GLY A C   1 
ATOM   2607 O  O   . GLY B 1 159 ? 31.721  -41.170 79.895  1.00 45.56  ? 159 GLY A O   1 
ATOM   2608 N  N   . LEU B 1 160 ? 32.743  -41.895 81.782  1.00 46.03  ? 160 LEU A N   1 
ATOM   2609 C  CA  . LEU B 1 160 ? 32.084  -40.927 82.646  1.00 47.53  ? 160 LEU A CA  1 
ATOM   2610 C  C   . LEU B 1 160 ? 32.490  -39.497 82.307  1.00 47.08  ? 160 LEU A C   1 
ATOM   2611 O  O   . LEU B 1 160 ? 31.652  -38.585 82.330  1.00 44.94  ? 160 LEU A O   1 
ATOM   2612 C  CB  . LEU B 1 160 ? 32.395  -41.248 84.103  1.00 48.56  ? 160 LEU A CB  1 
ATOM   2613 C  CG  . LEU B 1 160 ? 31.466  -40.445 85.002  1.00 57.34  ? 160 LEU A CG  1 
ATOM   2614 C  CD1 . LEU B 1 160 ? 30.053  -40.922 84.767  1.00 59.42  ? 160 LEU A CD1 1 
ATOM   2615 C  CD2 . LEU B 1 160 ? 31.841  -40.614 86.434  1.00 56.29  ? 160 LEU A CD2 1 
ATOM   2616 N  N   . GLY B 1 161 ? 33.767  -39.277 81.993  1.00 50.27  ? 161 GLY A N   1 
ATOM   2617 C  CA  . GLY B 1 161 ? 34.186  -37.952 81.587  1.00 41.41  ? 161 GLY A CA  1 
ATOM   2618 C  C   . GLY B 1 161 ? 33.496  -37.495 80.320  1.00 43.92  ? 161 GLY A C   1 
ATOM   2619 O  O   . GLY B 1 161 ? 33.211  -36.309 80.156  1.00 49.44  ? 161 GLY A O   1 
ATOM   2620 N  N   . GLU B 1 162 ? 33.205  -38.424 79.414  1.00 47.86  ? 162 GLU A N   1 
ATOM   2621 C  CA  . GLU B 1 162 ? 32.497  -38.045 78.203  1.00 48.73  ? 162 GLU A CA  1 
ATOM   2622 C  C   . GLU B 1 162 ? 31.086  -37.590 78.530  1.00 44.35  ? 162 GLU A C   1 
ATOM   2623 O  O   . GLU B 1 162 ? 30.619  -36.582 77.994  1.00 46.08  ? 162 GLU A O   1 
ATOM   2624 C  CB  . GLU B 1 162 ? 32.488  -39.208 77.214  1.00 48.75  ? 162 GLU A CB  1 
ATOM   2625 C  CG  . GLU B 1 162 ? 32.170  -38.808 75.781  1.00 49.44  ? 162 GLU A CG  1 
ATOM   2626 C  CD  . GLU B 1 162 ? 32.213  -39.996 74.846  1.00 53.72  ? 162 GLU A CD  1 
ATOM   2627 O  OE1 . GLU B 1 162 ? 32.134  -41.147 75.338  1.00 58.08  ? 162 GLU A OE1 1 
ATOM   2628 O  OE2 . GLU B 1 162 ? 32.343  -39.787 73.625  1.00 49.00  ? 162 GLU A OE2 1 
ATOM   2629 N  N   . CYS B 1 163 ? 30.407  -38.307 79.429  1.00 50.95  ? 163 CYS A N   1 
ATOM   2630 C  CA  . CYS B 1 163 ? 29.075  -37.905 79.887  1.00 50.47  ? 163 CYS A CA  1 
ATOM   2631 C  C   . CYS B 1 163 ? 29.083  -36.500 80.462  1.00 52.03  ? 163 CYS A C   1 
ATOM   2632 O  O   . CYS B 1 163 ? 28.208  -35.685 80.154  1.00 53.04  ? 163 CYS A O   1 
ATOM   2633 C  CB  . CYS B 1 163 ? 28.566  -38.859 80.962  1.00 51.82  ? 163 CYS A CB  1 
ATOM   2634 S  SG  . CYS B 1 163 ? 27.888  -40.384 80.387  1.00 68.10  ? 163 CYS A SG  1 
ATOM   2635 N  N   . MET B 1 164 ? 30.034  -36.214 81.351  1.00 51.55  ? 164 MET A N   1 
ATOM   2636 C  CA  . MET B 1 164 ? 30.001  -34.929 82.030  1.00 54.60  ? 164 MET A CA  1 
ATOM   2637 C  C   . MET B 1 164 ? 30.473  -33.799 81.132  1.00 55.93  ? 164 MET A C   1 
ATOM   2638 O  O   . MET B 1 164 ? 30.073  -32.642 81.331  1.00 52.03  ? 164 MET A O   1 
ATOM   2639 C  CB  . MET B 1 164 ? 30.812  -35.007 83.327  1.00 58.53  ? 164 MET A CB  1 
ATOM   2640 C  CG  . MET B 1 164 ? 29.914  -34.908 84.594  1.00 78.64  ? 164 MET A CG  1 
ATOM   2641 S  SD  . MET B 1 164 ? 28.487  -36.049 84.698  1.00 97.48  ? 164 MET A SD  1 
ATOM   2642 C  CE  . MET B 1 164 ? 29.279  -37.634 84.939  1.00 61.63  ? 164 MET A CE  1 
ATOM   2643 N  N   . PHE B 1 165 ? 31.280  -34.114 80.125  1.00 50.92  ? 165 PHE A N   1 
ATOM   2644 C  CA  . PHE B 1 165 ? 31.590  -33.123 79.109  1.00 44.61  ? 165 PHE A CA  1 
ATOM   2645 C  C   . PHE B 1 165 ? 30.349  -32.766 78.301  1.00 46.43  ? 165 PHE A C   1 
ATOM   2646 O  O   . PHE B 1 165 ? 30.066  -31.587 78.060  1.00 48.68  ? 165 PHE A O   1 
ATOM   2647 C  CB  . PHE B 1 165 ? 32.690  -33.654 78.206  1.00 41.14  ? 165 PHE A CB  1 
ATOM   2648 C  CG  . PHE B 1 165 ? 33.174  -32.659 77.217  1.00 47.04  ? 165 PHE A CG  1 
ATOM   2649 C  CD1 . PHE B 1 165 ? 34.251  -31.836 77.520  1.00 41.13  ? 165 PHE A CD1 1 
ATOM   2650 C  CD2 . PHE B 1 165 ? 32.556  -32.538 75.979  1.00 43.66  ? 165 PHE A CD2 1 
ATOM   2651 C  CE1 . PHE B 1 165 ? 34.706  -30.925 76.606  1.00 44.13  ? 165 PHE A CE1 1 
ATOM   2652 C  CE2 . PHE B 1 165 ? 33.008  -31.623 75.060  1.00 43.51  ? 165 PHE A CE2 1 
ATOM   2653 C  CZ  . PHE B 1 165 ? 34.090  -30.813 75.374  1.00 41.67  ? 165 PHE A CZ  1 
ATOM   2654 N  N   . ASP B 1 166 ? 29.593  -33.781 77.876  1.00 47.39  ? 166 ASP A N   1 
ATOM   2655 C  CA  . ASP B 1 166 ? 28.391  -33.535 77.090  1.00 47.10  ? 166 ASP A CA  1 
ATOM   2656 C  C   . ASP B 1 166 ? 27.400  -32.672 77.855  1.00 53.95  ? 166 ASP A C   1 
ATOM   2657 O  O   . ASP B 1 166 ? 26.757  -31.793 77.268  1.00 54.92  ? 166 ASP A O   1 
ATOM   2658 C  CB  . ASP B 1 166 ? 27.744  -34.858 76.693  1.00 45.51  ? 166 ASP A CB  1 
ATOM   2659 C  CG  . ASP B 1 166 ? 26.576  -34.670 75.748  1.00 46.18  ? 166 ASP A CG  1 
ATOM   2660 O  OD1 . ASP B 1 166 ? 26.805  -34.660 74.523  1.00 45.00  ? 166 ASP A OD1 1 
ATOM   2661 O  OD2 . ASP B 1 166 ? 25.428  -34.529 76.221  1.00 46.14  ? 166 ASP A OD2 1 
ATOM   2662 N  N   . LYS B 1 167 ? 27.274  -32.903 79.172  1.00 53.08  ? 167 LYS A N   1 
ATOM   2663 C  CA  . LYS B 1 167 ? 26.348  -32.122 79.990  1.00 59.49  ? 167 LYS A CA  1 
ATOM   2664 C  C   . LYS B 1 167 ? 26.772  -30.656 80.078  1.00 55.68  ? 167 LYS A C   1 
ATOM   2665 O  O   . LYS B 1 167 ? 25.936  -29.757 79.951  1.00 61.48  ? 167 LYS A O   1 
ATOM   2666 C  CB  . LYS B 1 167 ? 26.229  -32.729 81.390  1.00 56.27  ? 167 LYS A CB  1 
ATOM   2667 C  CG  . LYS B 1 167 ? 25.047  -32.159 82.180  1.00 63.62  ? 167 LYS A CG  1 
ATOM   2668 C  CD  . LYS B 1 167 ? 25.421  -31.804 83.620  1.00 72.57  ? 167 LYS A CD  1 
ATOM   2669 C  CE  . LYS B 1 167 ? 24.357  -30.906 84.276  1.00 72.38  ? 167 LYS A CE  1 
ATOM   2670 N  NZ  . LYS B 1 167 ? 24.838  -30.247 85.542  1.00 72.22  ? 167 LYS A NZ  1 
ATOM   2671 N  N   . GLU B 1 168 ? 28.058  -30.390 80.283  1.00 55.56  ? 168 GLU A N   1 
ATOM   2672 C  CA  . GLU B 1 168 ? 28.537  -29.013 80.402  1.00 59.49  ? 168 GLU A CA  1 
ATOM   2673 C  C   . GLU B 1 168 ? 28.687  -28.323 79.052  1.00 55.86  ? 168 GLU A C   1 
ATOM   2674 O  O   . GLU B 1 168 ? 29.248  -27.229 78.974  1.00 59.60  ? 168 GLU A O   1 
ATOM   2675 C  CB  . GLU B 1 168 ? 29.854  -28.991 81.174  1.00 48.46  ? 168 GLU A CB  1 
ATOM   2676 C  CG  . GLU B 1 168 ? 29.649  -29.386 82.635  1.00 59.01  ? 168 GLU A CG  1 
ATOM   2677 C  CD  . GLU B 1 168 ? 30.937  -29.423 83.427  1.00 67.34  ? 168 GLU A CD  1 
ATOM   2678 O  OE1 . GLU B 1 168 ? 31.073  -30.294 84.319  1.00 70.03  ? 168 GLU A OE1 1 
ATOM   2679 O  OE2 . GLU B 1 168 ? 31.818  -28.579 83.152  1.00 71.17  ? 168 GLU A OE2 1 
ATOM   2680 N  N   . LEU B 1 169 ? 28.210  -28.961 77.993  1.00 59.55  ? 169 LEU A N   1 
ATOM   2681 C  CA  . LEU B 1 169 ? 28.068  -28.385 76.663  1.00 66.70  ? 169 LEU A CA  1 
ATOM   2682 C  C   . LEU B 1 169 ? 26.655  -27.869 76.442  1.00 69.78  ? 169 LEU A C   1 
ATOM   2683 O  O   . LEU B 1 169 ? 26.448  -26.718 76.032  1.00 66.77  ? 169 LEU A O   1 
ATOM   2684 C  CB  . LEU B 1 169 ? 28.389  -29.459 75.618  1.00 55.71  ? 169 LEU A CB  1 
ATOM   2685 C  CG  . LEU B 1 169 ? 29.152  -29.125 74.363  1.00 50.68  ? 169 LEU A CG  1 
ATOM   2686 C  CD1 . LEU B 1 169 ? 30.236  -28.129 74.682  1.00 48.18  ? 169 LEU A CD1 1 
ATOM   2687 C  CD2 . LEU B 1 169 ? 29.742  -30.428 73.878  1.00 51.15  ? 169 LEU A CD2 1 
ATOM   2688 N  N   . ASN B 1 170 ? 25.681  -28.725 76.737  1.00 69.15  ? 170 ASN A N   1 
ATOM   2689 C  CA  . ASN B 1 170 ? 24.266  -28.439 76.616  1.00 74.73  ? 170 ASN A CA  1 
ATOM   2690 C  C   . ASN B 1 170 ? 23.820  -27.450 77.698  1.00 82.78  ? 170 ASN A C   1 
ATOM   2691 O  O   . ASN B 1 170 ? 24.655  -26.907 78.444  1.00 81.76  ? 170 ASN A O   1 
ATOM   2692 C  CB  . ASN B 1 170 ? 23.478  -29.750 76.707  1.00 68.63  ? 170 ASN A CB  1 
ATOM   2693 C  CG  . ASN B 1 170 ? 22.160  -29.696 75.956  1.00 75.24  ? 170 ASN A CG  1 
ATOM   2694 O  OD1 . ASN B 1 170 ? 21.654  -28.611 75.631  1.00 78.97  ? 170 ASN A OD1 1 
ATOM   2695 N  ND2 . ASN B 1 170 ? 21.596  -30.872 75.671  1.00 57.82  ? 170 ASN A ND2 1 
ATOM   2696 O  OXT . ASN B 1 170 ? 22.621  -27.175 77.845  1.00 82.82  ? 170 ASN A OXT 1 
ATOM   2697 N  N   . SER C 1 3   ? 7.672   -79.973 18.804  1.00 54.09  ? 3   SER C N   1 
ATOM   2698 C  CA  . SER C 1 3   ? 9.030   -79.885 18.254  1.00 59.11  ? 3   SER C CA  1 
ATOM   2699 C  C   . SER C 1 3   ? 10.104  -80.321 19.271  1.00 60.06  ? 3   SER C C   1 
ATOM   2700 O  O   . SER C 1 3   ? 10.120  -79.886 20.430  1.00 54.16  ? 3   SER C O   1 
ATOM   2701 C  CB  . SER C 1 3   ? 9.329   -78.463 17.751  1.00 56.40  ? 3   SER C CB  1 
ATOM   2702 O  OG  . SER C 1 3   ? 10.735  -78.206 17.687  1.00 48.87  ? 3   SER C OG  1 
ATOM   2703 N  N   . GLN C 1 4   ? 11.028  -81.162 18.797  1.00 50.95  ? 4   GLN C N   1 
ATOM   2704 C  CA  . GLN C 1 4   ? 11.918  -81.885 19.700  1.00 54.54  ? 4   GLN C CA  1 
ATOM   2705 C  C   . GLN C 1 4   ? 12.835  -80.950 20.497  1.00 58.36  ? 4   GLN C C   1 
ATOM   2706 O  O   . GLN C 1 4   ? 13.261  -81.304 21.608  1.00 57.73  ? 4   GLN C O   1 
ATOM   2707 C  CB  . GLN C 1 4   ? 12.724  -82.917 18.894  1.00 43.32  ? 4   GLN C CB  1 
ATOM   2708 C  CG  . GLN C 1 4   ? 13.831  -82.295 18.043  1.00 53.80  ? 4   GLN C CG  1 
ATOM   2709 C  CD  . GLN C 1 4   ? 14.454  -83.270 17.049  1.00 52.41  ? 4   GLN C CD  1 
ATOM   2710 O  OE1 . GLN C 1 4   ? 14.591  -84.459 17.333  1.00 62.36  ? 4   GLN C OE1 1 
ATOM   2711 N  NE2 . GLN C 1 4   ? 14.838  -82.760 15.875  1.00 45.02  ? 4   GLN C NE2 1 
ATOM   2712 N  N   . VAL C 1 5   ? 13.154  -79.762 19.965  1.00 57.40  ? 5   VAL C N   1 
ATOM   2713 C  CA  . VAL C 1 5   ? 14.080  -78.847 20.640  1.00 58.40  ? 5   VAL C CA  1 
ATOM   2714 C  C   . VAL C 1 5   ? 13.363  -77.783 21.466  1.00 59.33  ? 5   VAL C C   1 
ATOM   2715 O  O   . VAL C 1 5   ? 14.018  -77.091 22.267  1.00 57.30  ? 5   VAL C O   1 
ATOM   2716 C  CB  . VAL C 1 5   ? 15.041  -78.161 19.638  1.00 57.33  ? 5   VAL C CB  1 
ATOM   2717 C  CG1 . VAL C 1 5   ? 15.814  -79.202 18.794  1.00 49.51  ? 5   VAL C CG1 1 
ATOM   2718 C  CG2 . VAL C 1 5   ? 14.284  -77.157 18.759  1.00 51.84  ? 5   VAL C CG2 1 
ATOM   2719 N  N   . ARG C 1 6   ? 12.044  -77.643 21.308  1.00 60.75  ? 6   ARG C N   1 
ATOM   2720 C  CA  . ARG C 1 6   ? 11.281  -76.597 21.980  1.00 59.99  ? 6   ARG C CA  1 
ATOM   2721 C  C   . ARG C 1 6   ? 11.337  -76.770 23.499  1.00 58.71  ? 6   ARG C C   1 
ATOM   2722 O  O   . ARG C 1 6   ? 11.077  -77.862 24.021  1.00 63.39  ? 6   ARG C O   1 
ATOM   2723 C  CB  . ARG C 1 6   ? 9.836   -76.630 21.478  1.00 55.18  ? 6   ARG C CB  1 
ATOM   2724 C  CG  . ARG C 1 6   ? 9.144   -75.280 21.419  1.00 54.76  ? 6   ARG C CG  1 
ATOM   2725 C  CD  . ARG C 1 6   ? 7.642   -75.465 21.288  1.00 55.08  ? 6   ARG C CD  1 
ATOM   2726 N  NE  . ARG C 1 6   ? 6.920   -74.247 21.636  1.00 59.94  ? 6   ARG C NE  1 
ATOM   2727 C  CZ  . ARG C 1 6   ? 6.467   -73.372 20.748  1.00 52.14  ? 6   ARG C CZ  1 
ATOM   2728 N  NH1 . ARG C 1 6   ? 5.828   -72.286 21.154  1.00 60.03  ? 6   ARG C NH1 1 
ATOM   2729 N  NH2 . ARG C 1 6   ? 6.665   -73.581 19.457  1.00 39.49  ? 6   ARG C NH2 1 
ATOM   2730 N  N   . GLN C 1 7   ? 11.678  -75.688 24.209  1.00 54.94  ? 7   GLN C N   1 
ATOM   2731 C  CA  . GLN C 1 7   ? 11.823  -75.744 25.669  1.00 62.27  ? 7   GLN C CA  1 
ATOM   2732 C  C   . GLN C 1 7   ? 11.612  -74.344 26.239  1.00 56.01  ? 7   GLN C C   1 
ATOM   2733 O  O   . GLN C 1 7   ? 12.448  -73.467 26.017  1.00 61.59  ? 7   GLN C O   1 
ATOM   2734 C  CB  . GLN C 1 7   ? 13.203  -76.292 26.045  1.00 48.59  ? 7   GLN C CB  1 
ATOM   2735 C  CG  . GLN C 1 7   ? 13.247  -77.174 27.294  1.00 62.25  ? 7   GLN C CG  1 
ATOM   2736 C  CD  . GLN C 1 7   ? 14.643  -77.235 27.938  1.00 67.92  ? 7   GLN C CD  1 
ATOM   2737 O  OE1 . GLN C 1 7   ? 15.656  -76.924 27.301  1.00 72.38  ? 7   GLN C OE1 1 
ATOM   2738 N  NE2 . GLN C 1 7   ? 14.695  -77.647 29.201  1.00 56.02  ? 7   GLN C NE2 1 
ATOM   2739 N  N   . ASN C 1 8   ? 10.517  -74.139 26.984  1.00 63.80  ? 8   ASN C N   1 
ATOM   2740 C  CA  . ASN C 1 8   ? 10.227  -72.854 27.649  1.00 68.44  ? 8   ASN C CA  1 
ATOM   2741 C  C   . ASN C 1 8   ? 10.058  -71.733 26.617  1.00 65.42  ? 8   ASN C C   1 
ATOM   2742 O  O   . ASN C 1 8   ? 10.554  -70.613 26.772  1.00 59.63  ? 8   ASN C O   1 
ATOM   2743 C  CB  . ASN C 1 8   ? 11.303  -72.502 28.698  1.00 65.13  ? 8   ASN C CB  1 
ATOM   2744 C  CG  . ASN C 1 8   ? 11.091  -71.112 29.355  1.00 70.45  ? 8   ASN C CG  1 
ATOM   2745 O  OD1 . ASN C 1 8   ? 10.038  -70.841 29.938  1.00 67.25  ? 8   ASN C OD1 1 
ATOM   2746 N  ND2 . ASN C 1 8   ? 12.103  -70.237 29.255  1.00 60.68  ? 8   ASN C ND2 1 
ATOM   2747 N  N   . TYR C 1 9   ? 9.346   -72.044 25.543  1.00 64.64  ? 9   TYR C N   1 
ATOM   2748 C  CA  . TYR C 1 9   ? 9.134   -71.091 24.457  1.00 67.29  ? 9   TYR C CA  1 
ATOM   2749 C  C   . TYR C 1 9   ? 7.633   -70.860 24.343  1.00 61.21  ? 9   TYR C C   1 
ATOM   2750 O  O   . TYR C 1 9   ? 6.908   -71.693 23.784  1.00 59.72  ? 9   TYR C O   1 
ATOM   2751 C  CB  . TYR C 1 9   ? 9.745   -71.602 23.153  1.00 64.49  ? 9   TYR C CB  1 
ATOM   2752 C  CG  . TYR C 1 9   ? 9.880   -70.548 22.075  1.00 63.34  ? 9   TYR C CG  1 
ATOM   2753 C  CD1 . TYR C 1 9   ? 10.468  -69.304 22.348  1.00 61.10  ? 9   TYR C CD1 1 
ATOM   2754 C  CD2 . TYR C 1 9   ? 9.432   -70.798 20.774  1.00 60.54  ? 9   TYR C CD2 1 
ATOM   2755 C  CE1 . TYR C 1 9   ? 10.593  -68.336 21.350  1.00 56.41  ? 9   TYR C CE1 1 
ATOM   2756 C  CE2 . TYR C 1 9   ? 9.556   -69.842 19.768  1.00 55.42  ? 9   TYR C CE2 1 
ATOM   2757 C  CZ  . TYR C 1 9   ? 10.138  -68.621 20.062  1.00 55.60  ? 9   TYR C CZ  1 
ATOM   2758 O  OH  . TYR C 1 9   ? 10.248  -67.690 19.059  1.00 56.89  ? 9   TYR C OH  1 
ATOM   2759 N  N   . HIS C 1 10  ? 7.170   -69.733 24.875  1.00 60.42  ? 10  HIS C N   1 
ATOM   2760 C  CA  . HIS C 1 10  ? 5.738   -69.476 24.895  1.00 70.89  ? 10  HIS C CA  1 
ATOM   2761 C  C   . HIS C 1 10  ? 5.204   -69.274 23.480  1.00 71.53  ? 10  HIS C C   1 
ATOM   2762 O  O   . HIS C 1 10  ? 5.916   -68.827 22.574  1.00 68.08  ? 10  HIS C O   1 
ATOM   2763 C  CB  . HIS C 1 10  ? 5.405   -68.256 25.760  1.00 67.31  ? 10  HIS C CB  1 
ATOM   2764 C  CG  . HIS C 1 10  ? 3.987   -68.244 26.250  1.00 75.17  ? 10  HIS C CG  1 
ATOM   2765 N  ND1 . HIS C 1 10  ? 2.931   -67.811 25.472  1.00 76.62  ? 10  HIS C ND1 1 
ATOM   2766 C  CD2 . HIS C 1 10  ? 3.449   -68.625 27.433  1.00 69.44  ? 10  HIS C CD2 1 
ATOM   2767 C  CE1 . HIS C 1 10  ? 1.807   -67.921 26.157  1.00 70.44  ? 10  HIS C CE1 1 
ATOM   2768 N  NE2 . HIS C 1 10  ? 2.094   -68.411 27.349  1.00 73.93  ? 10  HIS C NE2 1 
ATOM   2769 N  N   . GLU C 1 11  ? 3.924   -69.617 23.306  1.00 70.27  ? 11  GLU C N   1 
ATOM   2770 C  CA  . GLU C 1 11  ? 3.269   -69.495 22.008  1.00 70.96  ? 11  GLU C CA  1 
ATOM   2771 C  C   . GLU C 1 11  ? 3.226   -68.049 21.526  1.00 68.81  ? 11  GLU C C   1 
ATOM   2772 O  O   . GLU C 1 11  ? 3.318   -67.790 20.317  1.00 65.21  ? 11  GLU C O   1 
ATOM   2773 C  CB  . GLU C 1 11  ? 1.854   -70.080 22.094  1.00 66.81  ? 11  GLU C CB  1 
ATOM   2774 C  CG  . GLU C 1 11  ? 1.743   -71.299 23.028  1.00 77.19  ? 11  GLU C CG  1 
ATOM   2775 C  CD  . GLU C 1 11  ? 2.436   -72.554 22.466  1.00 88.33  ? 11  GLU C CD  1 
ATOM   2776 O  OE1 . GLU C 1 11  ? 2.625   -72.623 21.226  1.00 88.74  ? 11  GLU C OE1 1 
ATOM   2777 O  OE2 . GLU C 1 11  ? 2.795   -73.467 23.258  1.00 82.10  ? 11  GLU C OE2 1 
ATOM   2778 N  N   . ASP C 1 12  ? 3.085   -67.093 22.440  1.00 68.56  ? 12  ASP C N   1 
ATOM   2779 C  CA  . ASP C 1 12  ? 2.924   -65.707 22.023  1.00 73.50  ? 12  ASP C CA  1 
ATOM   2780 C  C   . ASP C 1 12  ? 4.258   -65.015 21.764  1.00 66.56  ? 12  ASP C C   1 
ATOM   2781 O  O   . ASP C 1 12  ? 4.304   -64.046 20.992  1.00 57.60  ? 12  ASP C O   1 
ATOM   2782 C  CB  . ASP C 1 12  ? 2.077   -64.950 23.059  1.00 73.36  ? 12  ASP C CB  1 
ATOM   2783 C  CG  . ASP C 1 12  ? 0.650   -65.527 23.182  1.00 78.90  ? 12  ASP C CG  1 
ATOM   2784 O  OD1 . ASP C 1 12  ? 0.112   -65.588 24.313  1.00 85.86  ? 12  ASP C OD1 1 
ATOM   2785 O  OD2 . ASP C 1 12  ? 0.074   -65.934 22.143  1.00 70.92  ? 12  ASP C OD2 1 
ATOM   2786 N  N   . CYS C 1 13  ? 5.347   -65.514 22.352  1.00 65.36  ? 13  CYS C N   1 
ATOM   2787 C  CA  . CYS C 1 13  ? 6.673   -65.123 21.888  1.00 63.55  ? 13  CYS C CA  1 
ATOM   2788 C  C   . CYS C 1 13  ? 6.923   -65.605 20.465  1.00 60.92  ? 13  CYS C C   1 
ATOM   2789 O  O   . CYS C 1 13  ? 7.571   -64.911 19.673  1.00 56.78  ? 13  CYS C O   1 
ATOM   2790 C  CB  . CYS C 1 13  ? 7.736   -65.666 22.831  1.00 63.31  ? 13  CYS C CB  1 
ATOM   2791 S  SG  . CYS C 1 13  ? 7.530   -65.084 24.518  1.00 68.32  ? 13  CYS C SG  1 
ATOM   2792 N  N   . GLU C 1 14  ? 6.396   -66.782 20.120  1.00 64.68  ? 14  GLU C N   1 
ATOM   2793 C  CA  . GLU C 1 14  ? 6.552   -67.306 18.766  1.00 59.84  ? 14  GLU C CA  1 
ATOM   2794 C  C   . GLU C 1 14  ? 5.870   -66.407 17.737  1.00 57.15  ? 14  GLU C C   1 
ATOM   2795 O  O   . GLU C 1 14  ? 6.459   -66.090 16.695  1.00 51.49  ? 14  GLU C O   1 
ATOM   2796 C  CB  . GLU C 1 14  ? 6.014   -68.741 18.700  1.00 58.79  ? 14  GLU C CB  1 
ATOM   2797 C  CG  . GLU C 1 14  ? 5.942   -69.363 17.289  1.00 58.27  ? 14  GLU C CG  1 
ATOM   2798 C  CD  . GLU C 1 14  ? 5.575   -70.855 17.315  1.00 57.05  ? 14  GLU C CD  1 
ATOM   2799 O  OE1 . GLU C 1 14  ? 5.335   -71.390 18.420  1.00 53.66  ? 14  GLU C OE1 1 
ATOM   2800 O  OE2 . GLU C 1 14  ? 5.543   -71.491 16.237  1.00 56.38  ? 14  GLU C OE2 1 
ATOM   2801 N  N   . ALA C 1 15  ? 4.636   -65.965 18.017  1.00 55.88  ? 15  ALA C N   1 
ATOM   2802 C  CA  . ALA C 1 15  ? 3.909   -65.165 17.033  1.00 56.57  ? 15  ALA C CA  1 
ATOM   2803 C  C   . ALA C 1 15  ? 4.452   -63.742 16.958  1.00 56.40  ? 15  ALA C C   1 
ATOM   2804 O  O   . ALA C 1 15  ? 4.435   -63.122 15.889  1.00 51.77  ? 15  ALA C O   1 
ATOM   2805 C  CB  . ALA C 1 15  ? 2.417   -65.150 17.357  1.00 46.51  ? 15  ALA C CB  1 
ATOM   2806 N  N   . SER C 1 16  ? 4.944   -63.217 18.073  1.00 56.81  ? 16  SER C N   1 
ATOM   2807 C  CA  . SER C 1 16  ? 5.550   -61.895 18.050  1.00 56.60  ? 16  SER C CA  1 
ATOM   2808 C  C   . SER C 1 16  ? 6.847   -61.894 17.251  1.00 53.87  ? 16  SER C C   1 
ATOM   2809 O  O   . SER C 1 16  ? 7.144   -60.924 16.544  1.00 53.05  ? 16  SER C O   1 
ATOM   2810 C  CB  . SER C 1 16  ? 5.792   -61.418 19.480  1.00 60.72  ? 16  SER C CB  1 
ATOM   2811 O  OG  . SER C 1 16  ? 4.619   -60.833 20.012  1.00 72.16  ? 16  SER C OG  1 
ATOM   2812 N  N   . ILE C 1 17  ? 7.636   -62.966 17.351  1.00 50.20  ? 17  ILE C N   1 
ATOM   2813 C  CA  . ILE C 1 17  ? 8.836   -63.066 16.525  1.00 48.27  ? 17  ILE C CA  1 
ATOM   2814 C  C   . ILE C 1 17  ? 8.471   -62.977 15.046  1.00 48.55  ? 17  ILE C C   1 
ATOM   2815 O  O   . ILE C 1 17  ? 9.170   -62.330 14.260  1.00 45.37  ? 17  ILE C O   1 
ATOM   2816 C  CB  . ILE C 1 17  ? 9.608   -64.357 16.844  1.00 45.96  ? 17  ILE C CB  1 
ATOM   2817 C  CG1 . ILE C 1 17  ? 10.322  -64.247 18.198  1.00 49.65  ? 17  ILE C CG1 1 
ATOM   2818 C  CG2 . ILE C 1 17  ? 10.604  -64.665 15.745  1.00 40.37  ? 17  ILE C CG2 1 
ATOM   2819 C  CD1 . ILE C 1 17  ? 11.505  -63.321 18.190  1.00 50.48  ? 17  ILE C CD1 1 
ATOM   2820 N  N   . ASN C 1 18  ? 7.356   -63.591 14.647  1.00 48.38  ? 18  ASN C N   1 
ATOM   2821 C  CA  . ASN C 1 18  ? 6.990   -63.560 13.237  1.00 45.69  ? 18  ASN C CA  1 
ATOM   2822 C  C   . ASN C 1 18  ? 6.584   -62.167 12.782  1.00 48.14  ? 18  ASN C C   1 
ATOM   2823 O  O   . ASN C 1 18  ? 6.792   -61.815 11.610  1.00 48.25  ? 18  ASN C O   1 
ATOM   2824 C  CB  . ASN C 1 18  ? 5.881   -64.567 12.959  1.00 47.44  ? 18  ASN C CB  1 
ATOM   2825 C  CG  . ASN C 1 18  ? 6.406   -65.989 12.906  1.00 52.69  ? 18  ASN C CG  1 
ATOM   2826 O  OD1 . ASN C 1 18  ? 7.550   -66.214 12.514  1.00 49.71  ? 18  ASN C OD1 1 
ATOM   2827 N  ND2 . ASN C 1 18  ? 5.588   -66.952 13.320  1.00 46.41  ? 18  ASN C ND2 1 
ATOM   2828 N  N   . LYS C 1 19  ? 6.033   -61.350 13.677  1.00 43.27  ? 19  LYS C N   1 
ATOM   2829 C  CA  . LYS C 1 19  ? 5.651   -60.022 13.227  1.00 50.35  ? 19  LYS C CA  1 
ATOM   2830 C  C   . LYS C 1 19  ? 6.864   -59.107 13.146  1.00 48.58  ? 19  LYS C C   1 
ATOM   2831 O  O   . LYS C 1 19  ? 6.937   -58.252 12.263  1.00 50.67  ? 19  LYS C O   1 
ATOM   2832 C  CB  . LYS C 1 19  ? 4.577   -59.426 14.138  1.00 54.18  ? 19  LYS C CB  1 
ATOM   2833 C  CG  . LYS C 1 19  ? 3.849   -58.249 13.475  1.00 67.44  ? 19  LYS C CG  1 
ATOM   2834 C  CD  . LYS C 1 19  ? 3.801   -57.026 14.365  1.00 73.15  ? 19  LYS C CD  1 
ATOM   2835 C  CE  . LYS C 1 19  ? 3.778   -55.742 13.553  1.00 74.57  ? 19  LYS C CE  1 
ATOM   2836 N  NZ  . LYS C 1 19  ? 4.042   -54.603 14.477  1.00 72.37  ? 19  LYS C NZ  1 
ATOM   2837 N  N   . GLN C 1 20  ? 7.823   -59.279 14.055  1.00 45.36  ? 20  GLN C N   1 
ATOM   2838 C  CA  . GLN C 1 20  ? 9.088   -58.564 13.944  1.00 45.46  ? 20  GLN C CA  1 
ATOM   2839 C  C   . GLN C 1 20  ? 9.812   -58.925 12.653  1.00 48.01  ? 20  GLN C C   1 
ATOM   2840 O  O   . GLN C 1 20  ? 10.456  -58.068 12.036  1.00 43.05  ? 20  GLN C O   1 
ATOM   2841 C  CB  . GLN C 1 20  ? 9.973   -58.868 15.158  1.00 42.97  ? 20  GLN C CB  1 
ATOM   2842 C  CG  . GLN C 1 20  ? 11.036  -57.824 15.437  1.00 47.71  ? 20  GLN C CG  1 
ATOM   2843 C  CD  . GLN C 1 20  ? 10.443  -56.454 15.759  1.00 50.30  ? 20  GLN C CD  1 
ATOM   2844 O  OE1 . GLN C 1 20  ? 9.325   -56.350 16.254  1.00 52.99  ? 20  GLN C OE1 1 
ATOM   2845 N  NE2 . GLN C 1 20  ? 11.198  -55.400 15.481  1.00 49.47  ? 20  GLN C NE2 1 
ATOM   2846 N  N   . ILE C 1 21  ? 9.731   -60.195 12.235  1.00 43.33  ? 21  ILE C N   1 
ATOM   2847 C  CA  . ILE C 1 21  ? 10.343  -60.601 10.973  1.00 40.21  ? 21  ILE C CA  1 
ATOM   2848 C  C   . ILE C 1 21  ? 9.738   -59.813 9.823   1.00 39.35  ? 21  ILE C C   1 
ATOM   2849 O  O   . ILE C 1 21  ? 10.453  -59.291 8.955   1.00 36.87  ? 21  ILE C O   1 
ATOM   2850 C  CB  . ILE C 1 21  ? 10.180  -62.119 10.775  1.00 41.00  ? 21  ILE C CB  1 
ATOM   2851 C  CG1 . ILE C 1 21  ? 11.077  -62.865 11.771  1.00 38.40  ? 21  ILE C CG1 1 
ATOM   2852 C  CG2 . ILE C 1 21  ? 10.448  -62.495 9.295   1.00 32.79  ? 21  ILE C CG2 1 
ATOM   2853 C  CD1 . ILE C 1 21  ? 10.747  -64.320 11.945  1.00 38.88  ? 21  ILE C CD1 1 
ATOM   2854 N  N   . ASN C 1 22  ? 8.408   -59.685 9.823   1.00 38.82  ? 22  ASN C N   1 
ATOM   2855 C  CA  . ASN C 1 22  ? 7.725   -58.939 8.777   1.00 37.43  ? 22  ASN C CA  1 
ATOM   2856 C  C   . ASN C 1 22  ? 8.065   -57.462 8.864   1.00 41.58  ? 22  ASN C C   1 
ATOM   2857 O  O   . ASN C 1 22  ? 8.237   -56.791 7.838   1.00 42.75  ? 22  ASN C O   1 
ATOM   2858 C  CB  . ASN C 1 22  ? 6.209   -59.160 8.879   1.00 36.20  ? 22  ASN C CB  1 
ATOM   2859 C  CG  . ASN C 1 22  ? 5.453   -58.631 7.667   1.00 39.88  ? 22  ASN C CG  1 
ATOM   2860 O  OD1 . ASN C 1 22  ? 5.039   -57.466 7.644   1.00 39.10  ? 22  ASN C OD1 1 
ATOM   2861 N  ND2 . ASN C 1 22  ? 5.290   -59.480 6.638   1.00 39.17  ? 22  ASN C ND2 1 
ATOM   2862 N  N   . MET C 1 23  ? 8.170   -56.942 10.082  1.00 38.40  ? 23  MET C N   1 
ATOM   2863 C  CA  . MET C 1 23  ? 8.484   -55.534 10.253  1.00 40.95  ? 23  MET C CA  1 
ATOM   2864 C  C   . MET C 1 23  ? 9.859   -55.203 9.684   1.00 41.47  ? 23  MET C C   1 
ATOM   2865 O  O   . MET C 1 23  ? 10.029  -54.166 9.025   1.00 36.33  ? 23  MET C O   1 
ATOM   2866 C  CB  . MET C 1 23  ? 8.410   -55.165 11.728  1.00 39.78  ? 23  MET C CB  1 
ATOM   2867 C  CG  . MET C 1 23  ? 8.787   -53.729 11.982  1.00 53.95  ? 23  MET C CG  1 
ATOM   2868 S  SD  . MET C 1 23  ? 7.383   -52.645 11.679  1.00 72.58  ? 23  MET C SD  1 
ATOM   2869 C  CE  . MET C 1 23  ? 6.530   -52.882 13.237  1.00 66.28  ? 23  MET C CE  1 
ATOM   2870 N  N   . GLU C 1 24  ? 10.851  -56.079 9.918   1.00 40.66  ? 24  GLU C N   1 
ATOM   2871 C  CA  . GLU C 1 24  ? 12.193  -55.848 9.383   1.00 43.55  ? 24  GLU C CA  1 
ATOM   2872 C  C   . GLU C 1 24  ? 12.214  -55.989 7.861   1.00 39.87  ? 24  GLU C C   1 
ATOM   2873 O  O   . GLU C 1 24  ? 12.846  -55.176 7.172   1.00 33.67  ? 24  GLU C O   1 
ATOM   2874 C  CB  . GLU C 1 24  ? 13.206  -56.796 10.020  1.00 38.98  ? 24  GLU C CB  1 
ATOM   2875 C  CG  . GLU C 1 24  ? 13.187  -56.825 11.551  1.00 47.97  ? 24  GLU C CG  1 
ATOM   2876 C  CD  . GLU C 1 24  ? 14.006  -55.732 12.218  1.00 54.79  ? 24  GLU C CD  1 
ATOM   2877 O  OE1 . GLU C 1 24  ? 14.513  -54.834 11.512  1.00 55.92  ? 24  GLU C OE1 1 
ATOM   2878 O  OE2 . GLU C 1 24  ? 14.129  -55.767 13.466  1.00 62.06  ? 24  GLU C OE2 1 
ATOM   2879 N  N   . LEU C 1 25  ? 11.516  -56.996 7.315   1.00 37.59  ? 25  LEU C N   1 
ATOM   2880 C  CA  . LEU C 1 25  ? 11.442  -57.126 5.858   1.00 37.09  ? 25  LEU C CA  1 
ATOM   2881 C  C   . LEU C 1 25  ? 10.778  -55.907 5.231   1.00 38.17  ? 25  LEU C C   1 
ATOM   2882 O  O   . LEU C 1 25  ? 11.225  -55.411 4.184   1.00 40.96  ? 25  LEU C O   1 
ATOM   2883 C  CB  . LEU C 1 25  ? 10.696  -58.398 5.470   1.00 35.49  ? 25  LEU C CB  1 
ATOM   2884 C  CG  . LEU C 1 25  ? 11.367  -59.711 5.851   1.00 31.01  ? 25  LEU C CG  1 
ATOM   2885 C  CD1 . LEU C 1 25  ? 10.428  -60.905 5.552   1.00 29.36  ? 25  LEU C CD1 1 
ATOM   2886 C  CD2 . LEU C 1 25  ? 12.664  -59.844 5.076   1.00 30.63  ? 25  LEU C CD2 1 
ATOM   2887 N  N   . TYR C 1 26  ? 9.729   -55.392 5.876   1.00 35.81  ? 26  TYR C N   1 
ATOM   2888 C  CA  . TYR C 1 26  ? 9.095   -54.158 5.417   1.00 39.67  ? 26  TYR C CA  1 
ATOM   2889 C  C   . TYR C 1 26  ? 10.068  -52.988 5.445   1.00 36.73  ? 26  TYR C C   1 
ATOM   2890 O  O   . TYR C 1 26  ? 10.227  -52.282 4.442   1.00 33.76  ? 26  TYR C O   1 
ATOM   2891 C  CB  . TYR C 1 26  ? 7.870   -53.840 6.273   1.00 33.63  ? 26  TYR C CB  1 
ATOM   2892 C  CG  . TYR C 1 26  ? 7.271   -52.478 6.010   1.00 31.97  ? 26  TYR C CG  1 
ATOM   2893 C  CD1 . TYR C 1 26  ? 6.595   -52.211 4.823   1.00 37.00  ? 26  TYR C CD1 1 
ATOM   2894 C  CD2 . TYR C 1 26  ? 7.343   -51.465 6.964   1.00 36.07  ? 26  TYR C CD2 1 
ATOM   2895 C  CE1 . TYR C 1 26  ? 6.034   -50.960 4.581   1.00 37.52  ? 26  TYR C CE1 1 
ATOM   2896 C  CE2 . TYR C 1 26  ? 6.782   -50.208 6.734   1.00 35.98  ? 26  TYR C CE2 1 
ATOM   2897 C  CZ  . TYR C 1 26  ? 6.128   -49.967 5.541   1.00 34.47  ? 26  TYR C CZ  1 
ATOM   2898 O  OH  . TYR C 1 26  ? 5.562   -48.734 5.304   1.00 41.83  ? 26  TYR C OH  1 
ATOM   2899 N  N   . ALA C 1 27  ? 10.697  -52.741 6.604   1.00 36.31  ? 27  ALA C N   1 
ATOM   2900 C  CA  . ALA C 1 27  ? 11.658  -51.645 6.709   1.00 39.58  ? 27  ALA C CA  1 
ATOM   2901 C  C   . ALA C 1 27  ? 12.775  -51.788 5.673   1.00 34.13  ? 27  ALA C C   1 
ATOM   2902 O  O   . ALA C 1 27  ? 13.185  -50.800 5.063   1.00 34.79  ? 27  ALA C O   1 
ATOM   2903 C  CB  . ALA C 1 27  ? 12.238  -51.562 8.127   1.00 34.70  ? 27  ALA C CB  1 
ATOM   2904 N  N   . SER C 1 28  ? 13.234  -53.017 5.413   1.00 33.52  ? 28  SER C N   1 
ATOM   2905 C  CA  . SER C 1 28  ? 14.225  -53.219 4.358   1.00 38.34  ? 28  SER C CA  1 
ATOM   2906 C  C   . SER C 1 28  ? 13.674  -52.802 2.999   1.00 38.13  ? 28  SER C C   1 
ATOM   2907 O  O   . SER C 1 28  ? 14.414  -52.264 2.162   1.00 32.22  ? 28  SER C O   1 
ATOM   2908 C  CB  . SER C 1 28  ? 14.682  -54.677 4.324   1.00 33.62  ? 28  SER C CB  1 
ATOM   2909 O  OG  . SER C 1 28  ? 15.346  -54.982 3.098   1.00 30.89  ? 28  SER C OG  1 
ATOM   2910 N  N   . TYR C 1 29  ? 12.368  -53.033 2.771   1.00 37.94  ? 29  TYR C N   1 
ATOM   2911 C  CA  . TYR C 1 29  ? 11.713  -52.657 1.514   1.00 33.81  ? 29  TYR C CA  1 
ATOM   2912 C  C   . TYR C 1 29  ? 11.596  -51.141 1.376   1.00 36.67  ? 29  TYR C C   1 
ATOM   2913 O  O   . TYR C 1 29  ? 11.809  -50.591 0.290   1.00 35.99  ? 29  TYR C O   1 
ATOM   2914 C  CB  . TYR C 1 29  ? 10.331  -53.302 1.452   1.00 35.47  ? 29  TYR C CB  1 
ATOM   2915 C  CG  . TYR C 1 29  ? 9.675   -53.396 0.094   1.00 35.71  ? 29  TYR C CG  1 
ATOM   2916 C  CD1 . TYR C 1 29  ? 10.408  -53.286 -1.070  1.00 34.66  ? 29  TYR C CD1 1 
ATOM   2917 C  CD2 . TYR C 1 29  ? 8.305   -53.623 -0.013  1.00 36.28  ? 29  TYR C CD2 1 
ATOM   2918 C  CE1 . TYR C 1 29  ? 9.801   -53.395 -2.310  1.00 36.79  ? 29  TYR C CE1 1 
ATOM   2919 C  CE2 . TYR C 1 29  ? 7.690   -53.733 -1.239  1.00 36.31  ? 29  TYR C CE2 1 
ATOM   2920 C  CZ  . TYR C 1 29  ? 8.443   -53.617 -2.388  1.00 38.32  ? 29  TYR C CZ  1 
ATOM   2921 O  OH  . TYR C 1 29  ? 7.834   -53.712 -3.614  1.00 40.13  ? 29  TYR C OH  1 
ATOM   2922 N  N   . VAL C 1 30  ? 11.240  -50.449 2.458   1.00 34.94  ? 30  VAL C N   1 
ATOM   2923 C  CA  . VAL C 1 30  ? 11.200  -48.991 2.423   1.00 32.87  ? 30  VAL C CA  1 
ATOM   2924 C  C   . VAL C 1 30  ? 12.571  -48.437 2.045   1.00 36.95  ? 30  VAL C C   1 
ATOM   2925 O  O   . VAL C 1 30  ? 12.692  -47.615 1.130   1.00 40.29  ? 30  VAL C O   1 
ATOM   2926 C  CB  . VAL C 1 30  ? 10.723  -48.436 3.777   1.00 36.24  ? 30  VAL C CB  1 
ATOM   2927 C  CG1 . VAL C 1 30  ? 10.933  -46.933 3.839   1.00 33.90  ? 30  VAL C CG1 1 
ATOM   2928 C  CG2 . VAL C 1 30  ? 9.266   -48.792 4.024   1.00 37.32  ? 30  VAL C CG2 1 
ATOM   2929 N  N   . TYR C 1 31  ? 13.629  -48.878 2.744   1.00 35.44  ? 31  TYR C N   1 
ATOM   2930 C  CA  . TYR C 1 31  ? 14.968  -48.371 2.459   1.00 37.43  ? 31  TYR C CA  1 
ATOM   2931 C  C   . TYR C 1 31  ? 15.364  -48.652 1.020   1.00 39.01  ? 31  TYR C C   1 
ATOM   2932 O  O   . TYR C 1 31  ? 16.070  -47.851 0.402   1.00 36.94  ? 31  TYR C O   1 
ATOM   2933 C  CB  . TYR C 1 31  ? 15.997  -48.989 3.403   1.00 39.78  ? 31  TYR C CB  1 
ATOM   2934 C  CG  . TYR C 1 31  ? 15.991  -48.419 4.797   1.00 43.14  ? 31  TYR C CG  1 
ATOM   2935 C  CD1 . TYR C 1 31  ? 16.049  -47.047 5.004   1.00 44.35  ? 31  TYR C CD1 1 
ATOM   2936 C  CD2 . TYR C 1 31  ? 15.927  -49.259 5.914   1.00 44.19  ? 31  TYR C CD2 1 
ATOM   2937 C  CE1 . TYR C 1 31  ? 16.051  -46.520 6.279   1.00 50.65  ? 31  TYR C CE1 1 
ATOM   2938 C  CE2 . TYR C 1 31  ? 15.919  -48.748 7.191   1.00 44.99  ? 31  TYR C CE2 1 
ATOM   2939 C  CZ  . TYR C 1 31  ? 15.983  -47.373 7.369   1.00 53.47  ? 31  TYR C CZ  1 
ATOM   2940 O  OH  . TYR C 1 31  ? 15.975  -46.840 8.632   1.00 54.98  ? 31  TYR C OH  1 
ATOM   2941 N  N   . LEU C 1 32  ? 14.897  -49.769 0.465   1.00 35.60  ? 32  LEU C N   1 
ATOM   2942 C  CA  . LEU C 1 32  ? 15.131  -50.042 -0.946  1.00 31.89  ? 32  LEU C CA  1 
ATOM   2943 C  C   . LEU C 1 32  ? 14.426  -49.017 -1.831  1.00 37.79  ? 32  LEU C C   1 
ATOM   2944 O  O   . LEU C 1 32  ? 15.004  -48.541 -2.822  1.00 35.75  ? 32  LEU C O   1 
ATOM   2945 C  CB  . LEU C 1 32  ? 14.669  -51.458 -1.279  1.00 37.03  ? 32  LEU C CB  1 
ATOM   2946 C  CG  . LEU C 1 32  ? 15.067  -51.950 -2.672  1.00 42.83  ? 32  LEU C CG  1 
ATOM   2947 C  CD1 . LEU C 1 32  ? 16.578  -52.167 -2.697  1.00 34.81  ? 32  LEU C CD1 1 
ATOM   2948 C  CD2 . LEU C 1 32  ? 14.314  -53.236 -3.023  1.00 35.76  ? 32  LEU C CD2 1 
ATOM   2949 N  N   . SER C 1 33  ? 13.172  -48.685 -1.498  1.00 34.96  ? 33  SER C N   1 
ATOM   2950 C  CA  . SER C 1 33  ? 12.453  -47.607 -2.169  1.00 35.49  ? 33  SER C CA  1 
ATOM   2951 C  C   . SER C 1 33  ? 13.238  -46.306 -2.112  1.00 36.25  ? 33  SER C C   1 
ATOM   2952 O  O   . SER C 1 33  ? 13.484  -45.666 -3.138  1.00 34.65  ? 33  SER C O   1 
ATOM   2953 C  CB  . SER C 1 33  ? 11.075  -47.416 -1.530  1.00 34.79  ? 33  SER C CB  1 
ATOM   2954 O  OG  . SER C 1 33  ? 10.297  -46.517 -2.299  1.00 39.47  ? 33  SER C OG  1 
ATOM   2955 N  N   . MET C 1 34  ? 13.623  -45.889 -0.904  1.00 38.25  ? 34  MET C N   1 
ATOM   2956 C  CA  . MET C 1 34  ? 14.382  -44.652 -0.765  1.00 40.96  ? 34  MET C CA  1 
ATOM   2957 C  C   . MET C 1 34  ? 15.665  -44.690 -1.587  1.00 40.21  ? 34  MET C C   1 
ATOM   2958 O  O   . MET C 1 34  ? 15.996  -43.713 -2.275  1.00 39.18  ? 34  MET C O   1 
ATOM   2959 C  CB  . MET C 1 34  ? 14.702  -44.404 0.695   1.00 38.52  ? 34  MET C CB  1 
ATOM   2960 C  CG  . MET C 1 34  ? 13.501  -44.069 1.511   1.00 42.37  ? 34  MET C CG  1 
ATOM   2961 S  SD  . MET C 1 34  ? 14.006  -43.778 3.216   1.00 44.96  ? 34  MET C SD  1 
ATOM   2962 C  CE  . MET C 1 34  ? 12.376  -43.653 3.944   1.00 36.22  ? 34  MET C CE  1 
ATOM   2963 N  N   . ALA C 1 35  ? 16.372  -45.828 -1.563  1.00 37.57  ? 35  ALA C N   1 
ATOM   2964 C  CA  . ALA C 1 35  ? 17.671  -45.924 -2.226  1.00 39.18  ? 35  ALA C CA  1 
ATOM   2965 C  C   . ALA C 1 35  ? 17.563  -45.624 -3.716  1.00 39.16  ? 35  ALA C C   1 
ATOM   2966 O  O   . ALA C 1 35  ? 18.273  -44.757 -4.236  1.00 38.12  ? 35  ALA C O   1 
ATOM   2967 C  CB  . ALA C 1 35  ? 18.278  -47.303 -2.001  1.00 39.24  ? 35  ALA C CB  1 
ATOM   2968 N  N   . TYR C 1 36  ? 16.668  -46.321 -4.421  1.00 44.63  ? 36  TYR C N   1 
ATOM   2969 C  CA  . TYR C 1 36  ? 16.518  -46.092 -5.854  1.00 41.26  ? 36  TYR C CA  1 
ATOM   2970 C  C   . TYR C 1 36  ? 15.731  -44.827 -6.182  1.00 44.40  ? 36  TYR C C   1 
ATOM   2971 O  O   . TYR C 1 36  ? 15.815  -44.337 -7.317  1.00 43.36  ? 36  TYR C O   1 
ATOM   2972 C  CB  . TYR C 1 36  ? 15.896  -47.323 -6.521  1.00 38.69  ? 36  TYR C CB  1 
ATOM   2973 C  CG  . TYR C 1 36  ? 16.915  -48.441 -6.601  1.00 45.87  ? 36  TYR C CG  1 
ATOM   2974 C  CD1 . TYR C 1 36  ? 17.188  -49.229 -5.498  1.00 42.72  ? 36  TYR C CD1 1 
ATOM   2975 C  CD2 . TYR C 1 36  ? 17.668  -48.644 -7.747  1.00 45.74  ? 36  TYR C CD2 1 
ATOM   2976 C  CE1 . TYR C 1 36  ? 18.133  -50.222 -5.547  1.00 41.84  ? 36  TYR C CE1 1 
ATOM   2977 C  CE2 . TYR C 1 36  ? 18.621  -49.629 -7.801  1.00 46.97  ? 36  TYR C CE2 1 
ATOM   2978 C  CZ  . TYR C 1 36  ? 18.846  -50.421 -6.693  1.00 47.99  ? 36  TYR C CZ  1 
ATOM   2979 O  OH  . TYR C 1 36  ? 19.790  -51.423 -6.728  1.00 46.49  ? 36  TYR C OH  1 
ATOM   2980 N  N   . TYR C 1 37  ? 14.995  -44.259 -5.223  1.00 41.27  ? 37  TYR C N   1 
ATOM   2981 C  CA  . TYR C 1 37  ? 14.463  -42.922 -5.453  1.00 38.46  ? 37  TYR C CA  1 
ATOM   2982 C  C   . TYR C 1 37  ? 15.602  -41.921 -5.599  1.00 44.24  ? 37  TYR C C   1 
ATOM   2983 O  O   . TYR C 1 37  ? 15.535  -41.000 -6.421  1.00 37.66  ? 37  TYR C O   1 
ATOM   2984 C  CB  . TYR C 1 37  ? 13.523  -42.514 -4.322  1.00 41.55  ? 37  TYR C CB  1 
ATOM   2985 C  CG  . TYR C 1 37  ? 13.237  -41.029 -4.269  1.00 42.12  ? 37  TYR C CG  1 
ATOM   2986 C  CD1 . TYR C 1 37  ? 12.286  -40.447 -5.107  1.00 45.97  ? 37  TYR C CD1 1 
ATOM   2987 C  CD2 . TYR C 1 37  ? 13.926  -40.207 -3.384  1.00 42.28  ? 37  TYR C CD2 1 
ATOM   2988 C  CE1 . TYR C 1 37  ? 12.026  -39.085 -5.065  1.00 41.83  ? 37  TYR C CE1 1 
ATOM   2989 C  CE2 . TYR C 1 37  ? 13.679  -38.839 -3.336  1.00 46.50  ? 37  TYR C CE2 1 
ATOM   2990 C  CZ  . TYR C 1 37  ? 12.725  -38.288 -4.178  1.00 47.87  ? 37  TYR C CZ  1 
ATOM   2991 O  OH  . TYR C 1 37  ? 12.483  -36.938 -4.125  1.00 50.00  ? 37  TYR C OH  1 
ATOM   2992 N  N   . PHE C 1 38  ? 16.668  -42.098 -4.820  1.00 38.47  ? 38  PHE C N   1 
ATOM   2993 C  CA  . PHE C 1 38  ? 17.756  -41.143 -4.867  1.00 42.83  ? 38  PHE C CA  1 
ATOM   2994 C  C   . PHE C 1 38  ? 18.713  -41.414 -6.019  1.00 44.33  ? 38  PHE C C   1 
ATOM   2995 O  O   . PHE C 1 38  ? 19.586  -40.581 -6.293  1.00 38.54  ? 38  PHE C O   1 
ATOM   2996 C  CB  . PHE C 1 38  ? 18.461  -41.105 -3.507  1.00 35.46  ? 38  PHE C CB  1 
ATOM   2997 C  CG  . PHE C 1 38  ? 17.674  -40.327 -2.485  1.00 43.07  ? 38  PHE C CG  1 
ATOM   2998 C  CD1 . PHE C 1 38  ? 17.647  -38.939 -2.529  1.00 40.30  ? 38  PHE C CD1 1 
ATOM   2999 C  CD2 . PHE C 1 38  ? 16.890  -40.975 -1.542  1.00 38.99  ? 38  PHE C CD2 1 
ATOM   3000 C  CE1 . PHE C 1 38  ? 16.890  -38.205 -1.617  1.00 44.55  ? 38  PHE C CE1 1 
ATOM   3001 C  CE2 . PHE C 1 38  ? 16.124  -40.253 -0.635  1.00 39.93  ? 38  PHE C CE2 1 
ATOM   3002 C  CZ  . PHE C 1 38  ? 16.126  -38.858 -0.669  1.00 44.48  ? 38  PHE C CZ  1 
ATOM   3003 N  N   . GLU C 1 39  ? 18.526  -42.512 -6.741  1.00 42.31  ? 39  GLU C N   1 
ATOM   3004 C  CA  . GLU C 1 39  ? 19.258  -42.732 -7.979  1.00 43.27  ? 39  GLU C CA  1 
ATOM   3005 C  C   . GLU C 1 39  ? 18.496  -42.247 -9.212  1.00 41.49  ? 39  GLU C C   1 
ATOM   3006 O  O   . GLU C 1 39  ? 19.014  -42.373 -10.324 1.00 45.93  ? 39  GLU C O   1 
ATOM   3007 C  CB  . GLU C 1 39  ? 19.612  -44.211 -8.117  1.00 36.66  ? 39  GLU C CB  1 
ATOM   3008 C  CG  . GLU C 1 39  ? 20.784  -44.625 -7.262  1.00 41.90  ? 39  GLU C CG  1 
ATOM   3009 C  CD  . GLU C 1 39  ? 21.252  -46.041 -7.560  1.00 43.99  ? 39  GLU C CD  1 
ATOM   3010 O  OE1 . GLU C 1 39  ? 20.603  -46.720 -8.377  1.00 47.64  ? 39  GLU C OE1 1 
ATOM   3011 O  OE2 . GLU C 1 39  ? 22.268  -46.475 -6.981  1.00 55.59  ? 39  GLU C OE2 1 
ATOM   3012 N  N   . ARG C 1 40  ? 17.294  -41.691 -9.040  1.00 45.90  ? 40  ARG C N   1 
ATOM   3013 C  CA  . ARG C 1 40  ? 16.543  -41.122 -10.156 1.00 46.58  ? 40  ARG C CA  1 
ATOM   3014 C  C   . ARG C 1 40  ? 17.345  -40.006 -10.812 1.00 50.74  ? 40  ARG C C   1 
ATOM   3015 O  O   . ARG C 1 40  ? 18.126  -39.312 -10.153 1.00 48.56  ? 40  ARG C O   1 
ATOM   3016 C  CB  . ARG C 1 40  ? 15.202  -40.565 -9.685  1.00 44.38  ? 40  ARG C CB  1 
ATOM   3017 C  CG  . ARG C 1 40  ? 14.036  -41.509 -9.797  1.00 47.96  ? 40  ARG C CG  1 
ATOM   3018 C  CD  . ARG C 1 40  ? 12.806  -40.989 -9.052  1.00 46.77  ? 40  ARG C CD  1 
ATOM   3019 N  NE  . ARG C 1 40  ? 12.508  -39.590 -9.351  1.00 60.25  ? 40  ARG C NE  1 
ATOM   3020 C  CZ  . ARG C 1 40  ? 11.369  -38.973 -9.023  1.00 66.89  ? 40  ARG C CZ  1 
ATOM   3021 N  NH1 . ARG C 1 40  ? 10.406  -39.634 -8.384  1.00 68.54  ? 40  ARG C NH1 1 
ATOM   3022 N  NH2 . ARG C 1 40  ? 11.190  -37.689 -9.319  1.00 57.13  ? 40  ARG C NH2 1 
ATOM   3023 N  N   . ASP C 1 41  ? 17.135  -39.838 -12.127 1.00 51.27  ? 41  ASP C N   1 
ATOM   3024 C  CA  . ASP C 1 41  ? 17.900  -38.872 -12.916 1.00 52.94  ? 41  ASP C CA  1 
ATOM   3025 C  C   . ASP C 1 41  ? 17.615  -37.430 -12.494 1.00 56.10  ? 41  ASP C C   1 
ATOM   3026 O  O   . ASP C 1 41  ? 18.510  -36.581 -12.574 1.00 58.67  ? 41  ASP C O   1 
ATOM   3027 C  CB  . ASP C 1 41  ? 17.631  -39.066 -14.420 1.00 55.09  ? 41  ASP C CB  1 
ATOM   3028 C  CG  . ASP C 1 41  ? 16.141  -38.979 -14.793 1.00 62.95  ? 41  ASP C CG  1 
ATOM   3029 O  OD1 . ASP C 1 41  ? 15.292  -39.730 -14.249 1.00 68.88  ? 41  ASP C OD1 1 
ATOM   3030 O  OD2 . ASP C 1 41  ? 15.818  -38.153 -15.667 1.00 68.23  ? 41  ASP C OD2 1 
ATOM   3031 N  N   . ASP C 1 42  ? 16.407  -37.141 -12.010 1.00 49.47  ? 42  ASP C N   1 
ATOM   3032 C  CA  . ASP C 1 42  ? 16.052  -35.809 -11.536 1.00 51.17  ? 42  ASP C CA  1 
ATOM   3033 C  C   . ASP C 1 42  ? 16.299  -35.612 -10.033 1.00 48.95  ? 42  ASP C C   1 
ATOM   3034 O  O   . ASP C 1 42  ? 15.834  -34.617 -9.467  1.00 47.15  ? 42  ASP C O   1 
ATOM   3035 C  CB  . ASP C 1 42  ? 14.585  -35.511 -11.861 1.00 43.08  ? 42  ASP C CB  1 
ATOM   3036 C  CG  . ASP C 1 42  ? 13.636  -36.541 -11.273 1.00 50.06  ? 42  ASP C CG  1 
ATOM   3037 O  OD1 . ASP C 1 42  ? 14.109  -37.626 -10.880 1.00 54.69  ? 42  ASP C OD1 1 
ATOM   3038 O  OD2 . ASP C 1 42  ? 12.424  -36.267 -11.192 1.00 52.12  ? 42  ASP C OD2 1 
ATOM   3039 N  N   . VAL C 1 43  ? 17.000  -36.537 -9.377  1.00 44.98  ? 43  VAL C N   1 
ATOM   3040 C  CA  . VAL C 1 43  ? 17.346  -36.414 -7.963  1.00 42.82  ? 43  VAL C CA  1 
ATOM   3041 C  C   . VAL C 1 43  ? 18.861  -36.527 -7.823  1.00 44.18  ? 43  VAL C C   1 
ATOM   3042 O  O   . VAL C 1 43  ? 19.541  -35.576 -7.435  1.00 41.38  ? 43  VAL C O   1 
ATOM   3043 C  CB  . VAL C 1 43  ? 16.636  -37.484 -7.107  1.00 40.64  ? 43  VAL C CB  1 
ATOM   3044 C  CG1 . VAL C 1 43  ? 17.065  -37.365 -5.656  1.00 38.54  ? 43  VAL C CG1 1 
ATOM   3045 C  CG2 . VAL C 1 43  ? 15.131  -37.372 -7.211  1.00 35.73  ? 43  VAL C CG2 1 
ATOM   3046 N  N   . CYS C 1 44  ? 19.388  -37.715 -8.094  1.00 48.00  ? 44  CYS C N   1 
ATOM   3047 C  CA  . CYS C 1 44  ? 20.817  -37.958 -8.269  1.00 45.55  ? 44  CYS C CA  1 
ATOM   3048 C  C   . CYS C 1 44  ? 21.631  -37.506 -7.048  1.00 47.72  ? 44  CYS C C   1 
ATOM   3049 O  O   . CYS C 1 44  ? 22.525  -36.662 -7.125  1.00 48.65  ? 44  CYS C O   1 
ATOM   3050 C  CB  . CYS C 1 44  ? 21.285  -37.299 -9.569  1.00 53.43  ? 44  CYS C CB  1 
ATOM   3051 S  SG  . CYS C 1 44  ? 20.802  -38.277 -11.072 1.00 88.29  ? 44  CYS C SG  1 
ATOM   3052 N  N   . LEU C 1 45  ? 21.302  -38.108 -5.901  1.00 40.15  ? 45  LEU C N   1 
ATOM   3053 C  CA  . LEU C 1 45  ? 22.069  -37.949 -4.671  1.00 42.97  ? 45  LEU C CA  1 
ATOM   3054 C  C   . LEU C 1 45  ? 22.692  -39.305 -4.343  1.00 46.76  ? 45  LEU C C   1 
ATOM   3055 O  O   . LEU C 1 45  ? 22.103  -40.118 -3.611  1.00 41.22  ? 45  LEU C O   1 
ATOM   3056 C  CB  . LEU C 1 45  ? 21.179  -37.440 -3.533  1.00 39.18  ? 45  LEU C CB  1 
ATOM   3057 C  CG  . LEU C 1 45  ? 20.851  -35.944 -3.651  1.00 39.93  ? 45  LEU C CG  1 
ATOM   3058 C  CD1 . LEU C 1 45  ? 19.697  -35.518 -2.748  1.00 40.58  ? 45  LEU C CD1 1 
ATOM   3059 C  CD2 . LEU C 1 45  ? 22.089  -35.102 -3.351  1.00 41.74  ? 45  LEU C CD2 1 
ATOM   3060 N  N   . PRO C 1 46  ? 23.872  -39.611 -4.889  1.00 48.33  ? 46  PRO C N   1 
ATOM   3061 C  CA  . PRO C 1 46  ? 24.441  -40.967 -4.710  1.00 44.76  ? 46  PRO C CA  1 
ATOM   3062 C  C   . PRO C 1 46  ? 24.837  -41.306 -3.281  1.00 42.04  ? 46  PRO C C   1 
ATOM   3063 O  O   . PRO C 1 46  ? 24.807  -42.486 -2.915  1.00 44.99  ? 46  PRO C O   1 
ATOM   3064 C  CB  . PRO C 1 46  ? 25.666  -40.971 -5.643  1.00 36.80  ? 46  PRO C CB  1 
ATOM   3065 C  CG  . PRO C 1 46  ? 25.934  -39.497 -5.951  1.00 50.44  ? 46  PRO C CG  1 
ATOM   3066 C  CD  . PRO C 1 46  ? 24.590  -38.817 -5.900  1.00 42.18  ? 46  PRO C CD  1 
ATOM   3067 N  N   . GLY C 1 47  ? 25.242  -40.326 -2.474  1.00 45.32  ? 47  GLY C N   1 
ATOM   3068 C  CA  . GLY C 1 47  ? 25.512  -40.603 -1.075  1.00 39.68  ? 47  GLY C CA  1 
ATOM   3069 C  C   . GLY C 1 47  ? 24.278  -41.095 -0.342  1.00 46.32  ? 47  GLY C C   1 
ATOM   3070 O  O   . GLY C 1 47  ? 24.320  -42.110 0.367   1.00 41.95  ? 47  GLY C O   1 
ATOM   3071 N  N   . PHE C 1 48  ? 23.156  -40.378 -0.497  1.00 41.68  ? 48  PHE C N   1 
ATOM   3072 C  CA  . PHE C 1 48  ? 21.893  -40.837 0.080   1.00 44.33  ? 48  PHE C CA  1 
ATOM   3073 C  C   . PHE C 1 48  ? 21.546  -42.241 -0.406  1.00 42.27  ? 48  PHE C C   1 
ATOM   3074 O  O   . PHE C 1 48  ? 21.142  -43.101 0.392   1.00 37.28  ? 48  PHE C O   1 
ATOM   3075 C  CB  . PHE C 1 48  ? 20.755  -39.870 -0.267  1.00 37.64  ? 48  PHE C CB  1 
ATOM   3076 C  CG  . PHE C 1 48  ? 20.712  -38.632 0.589   1.00 40.38  ? 48  PHE C CG  1 
ATOM   3077 C  CD1 . PHE C 1 48  ? 21.400  -37.483 0.215   1.00 42.64  ? 48  PHE C CD1 1 
ATOM   3078 C  CD2 . PHE C 1 48  ? 19.969  -38.606 1.756   1.00 43.69  ? 48  PHE C CD2 1 
ATOM   3079 C  CE1 . PHE C 1 48  ? 21.354  -36.332 1.000   1.00 42.23  ? 48  PHE C CE1 1 
ATOM   3080 C  CE2 . PHE C 1 48  ? 19.919  -37.454 2.548   1.00 43.53  ? 48  PHE C CE2 1 
ATOM   3081 C  CZ  . PHE C 1 48  ? 20.611  -36.318 2.163   1.00 40.87  ? 48  PHE C CZ  1 
ATOM   3082 N  N   . ALA C 1 49  ? 21.726  -42.493 -1.709  1.00 35.68  ? 49  ALA C N   1 
ATOM   3083 C  CA  . ALA C 1 49  ? 21.331  -43.770 -2.289  1.00 38.21  ? 49  ALA C CA  1 
ATOM   3084 C  C   . ALA C 1 49  ? 22.126  -44.910 -1.673  1.00 42.53  ? 49  ALA C C   1 
ATOM   3085 O  O   . ALA C 1 49  ? 21.560  -45.948 -1.303  1.00 42.43  ? 49  ALA C O   1 
ATOM   3086 C  CB  . ALA C 1 49  ? 21.514  -43.748 -3.811  1.00 34.83  ? 49  ALA C CB  1 
ATOM   3087 N  N   . LYS C 1 50  ? 23.445  -44.733 -1.558  1.00 39.29  ? 50  LYS C N   1 
ATOM   3088 C  CA  . LYS C 1 50  ? 24.276  -45.760 -0.946  1.00 38.77  ? 50  LYS C CA  1 
ATOM   3089 C  C   . LYS C 1 50  ? 23.861  -45.990 0.501   1.00 41.07  ? 50  LYS C C   1 
ATOM   3090 O  O   . LYS C 1 50  ? 23.696  -47.136 0.936   1.00 44.22  ? 50  LYS C O   1 
ATOM   3091 C  CB  . LYS C 1 50  ? 25.757  -45.375 -1.047  1.00 44.48  ? 50  LYS C CB  1 
ATOM   3092 C  CG  . LYS C 1 50  ? 26.687  -46.189 -0.149  1.00 45.75  ? 50  LYS C CG  1 
ATOM   3093 C  CD  . LYS C 1 50  ? 28.013  -46.448 -0.818  1.00 55.19  ? 50  LYS C CD  1 
ATOM   3094 C  CE  . LYS C 1 50  ? 29.145  -46.475 0.192   1.00 66.87  ? 50  LYS C CE  1 
ATOM   3095 N  NZ  . LYS C 1 50  ? 30.373  -45.860 -0.388  1.00 71.90  ? 50  LYS C NZ  1 
ATOM   3096 N  N   . PHE C 1 51  ? 23.651  -44.909 1.252   1.00 31.73  ? 51  PHE C N   1 
ATOM   3097 C  CA  . PHE C 1 51  ? 23.259  -45.061 2.647   1.00 37.38  ? 51  PHE C CA  1 
ATOM   3098 C  C   . PHE C 1 51  ? 21.991  -45.901 2.776   1.00 47.53  ? 51  PHE C C   1 
ATOM   3099 O  O   . PHE C 1 51  ? 21.912  -46.789 3.639   1.00 38.99  ? 51  PHE C O   1 
ATOM   3100 C  CB  . PHE C 1 51  ? 23.059  -43.691 3.294   1.00 37.07  ? 51  PHE C CB  1 
ATOM   3101 C  CG  . PHE C 1 51  ? 22.613  -43.760 4.722   1.00 37.19  ? 51  PHE C CG  1 
ATOM   3102 C  CD1 . PHE C 1 51  ? 23.529  -43.936 5.738   1.00 31.74  ? 51  PHE C CD1 1 
ATOM   3103 C  CD2 . PHE C 1 51  ? 21.269  -43.657 5.049   1.00 39.35  ? 51  PHE C CD2 1 
ATOM   3104 C  CE1 . PHE C 1 51  ? 23.115  -44.000 7.060   1.00 40.96  ? 51  PHE C CE1 1 
ATOM   3105 C  CE2 . PHE C 1 51  ? 20.854  -43.726 6.377   1.00 43.18  ? 51  PHE C CE2 1 
ATOM   3106 C  CZ  . PHE C 1 51  ? 21.779  -43.899 7.381   1.00 36.59  ? 51  PHE C CZ  1 
ATOM   3107 N  N   . PHE C 1 52  ? 20.998  -45.661 1.900   1.00 42.60  ? 52  PHE C N   1 
ATOM   3108 C  CA  . PHE C 1 52  ? 19.733  -46.371 2.045   1.00 40.00  ? 52  PHE C CA  1 
ATOM   3109 C  C   . PHE C 1 52  ? 19.820  -47.779 1.482   1.00 40.57  ? 52  PHE C C   1 
ATOM   3110 O  O   . PHE C 1 52  ? 19.116  -48.670 1.967   1.00 44.04  ? 52  PHE C O   1 
ATOM   3111 C  CB  . PHE C 1 52  ? 18.594  -45.570 1.405   1.00 35.70  ? 52  PHE C CB  1 
ATOM   3112 C  CG  . PHE C 1 52  ? 18.186  -44.358 2.211   1.00 35.48  ? 52  PHE C CG  1 
ATOM   3113 C  CD1 . PHE C 1 52  ? 17.870  -44.474 3.554   1.00 41.34  ? 52  PHE C CD1 1 
ATOM   3114 C  CD2 . PHE C 1 52  ? 18.169  -43.106 1.639   1.00 36.94  ? 52  PHE C CD2 1 
ATOM   3115 C  CE1 . PHE C 1 52  ? 17.517  -43.367 4.305   1.00 40.37  ? 52  PHE C CE1 1 
ATOM   3116 C  CE2 . PHE C 1 52  ? 17.799  -41.994 2.380   1.00 36.95  ? 52  PHE C CE2 1 
ATOM   3117 C  CZ  . PHE C 1 52  ? 17.478  -42.134 3.720   1.00 42.52  ? 52  PHE C CZ  1 
ATOM   3118 N  N   . LYS C 1 53  ? 20.708  -48.009 0.507   1.00 39.81  ? 53  LYS C N   1 
ATOM   3119 C  CA  . LYS C 1 53  ? 20.960  -49.374 0.045   1.00 43.04  ? 53  LYS C CA  1 
ATOM   3120 C  C   . LYS C 1 53  ? 21.492  -50.227 1.183   1.00 42.77  ? 53  LYS C C   1 
ATOM   3121 O  O   . LYS C 1 53  ? 21.062  -51.370 1.372   1.00 44.92  ? 53  LYS C O   1 
ATOM   3122 C  CB  . LYS C 1 53  ? 21.962  -49.389 -1.116  1.00 33.91  ? 53  LYS C CB  1 
ATOM   3123 C  CG  . LYS C 1 53  ? 21.415  -49.782 -2.470  1.00 48.81  ? 53  LYS C CG  1 
ATOM   3124 C  CD  . LYS C 1 53  ? 22.080  -48.943 -3.586  1.00 58.15  ? 53  LYS C CD  1 
ATOM   3125 C  CE  . LYS C 1 53  ? 21.762  -49.462 -4.994  1.00 56.14  ? 53  LYS C CE  1 
ATOM   3126 N  NZ  . LYS C 1 53  ? 22.687  -48.862 -6.002  1.00 56.74  ? 53  LYS C NZ  1 
ATOM   3127 N  N   . GLU C 1 54  ? 22.417  -49.673 1.964   1.00 41.09  ? 54  GLU C N   1 
ATOM   3128 C  CA  . GLU C 1 54  ? 23.028  -50.433 3.042   1.00 42.32  ? 54  GLU C CA  1 
ATOM   3129 C  C   . GLU C 1 54  ? 22.038  -50.674 4.168   1.00 42.31  ? 54  GLU C C   1 
ATOM   3130 O  O   . GLU C 1 54  ? 21.935  -51.795 4.681   1.00 46.36  ? 54  GLU C O   1 
ATOM   3131 C  CB  . GLU C 1 54  ? 24.274  -49.716 3.553   1.00 40.14  ? 54  GLU C CB  1 
ATOM   3132 C  CG  . GLU C 1 54  ? 25.473  -49.909 2.633   1.00 41.04  ? 54  GLU C CG  1 
ATOM   3133 C  CD  . GLU C 1 54  ? 26.583  -48.912 2.887   1.00 52.59  ? 54  GLU C CD  1 
ATOM   3134 O  OE1 . GLU C 1 54  ? 26.532  -48.202 3.918   1.00 60.81  ? 54  GLU C OE1 1 
ATOM   3135 O  OE2 . GLU C 1 54  ? 27.510  -48.843 2.052   1.00 68.41  ? 54  GLU C OE2 1 
ATOM   3136 N  N   . SER C 1 55  ? 21.297  -49.639 4.568   1.00 38.03  ? 55  SER C N   1 
ATOM   3137 C  CA  . SER C 1 55  ? 20.258  -49.854 5.567   1.00 43.90  ? 55  SER C CA  1 
ATOM   3138 C  C   . SER C 1 55  ? 19.242  -50.893 5.107   1.00 42.13  ? 55  SER C C   1 
ATOM   3139 O  O   . SER C 1 55  ? 18.692  -51.618 5.943   1.00 41.17  ? 55  SER C O   1 
ATOM   3140 C  CB  . SER C 1 55  ? 19.553  -48.544 5.923   1.00 42.51  ? 55  SER C CB  1 
ATOM   3141 O  OG  . SER C 1 55  ? 20.468  -47.477 6.026   1.00 41.63  ? 55  SER C OG  1 
ATOM   3142 N  N   . SER C 1 56  ? 19.010  -51.024 3.794   1.00 35.34  ? 56  SER C N   1 
ATOM   3143 C  CA  . SER C 1 56  ? 18.040  -52.032 3.374   1.00 42.58  ? 56  SER C CA  1 
ATOM   3144 C  C   . SER C 1 56  ? 18.635  -53.434 3.474   1.00 38.16  ? 56  SER C C   1 
ATOM   3145 O  O   . SER C 1 56  ? 17.930  -54.379 3.836   1.00 39.96  ? 56  SER C O   1 
ATOM   3146 C  CB  . SER C 1 56  ? 17.528  -51.750 1.954   1.00 40.40  ? 56  SER C CB  1 
ATOM   3147 O  OG  . SER C 1 56  ? 17.010  -52.922 1.328   1.00 35.44  ? 56  SER C OG  1 
ATOM   3148 N  N   . ASP C 1 57  ? 19.936  -53.574 3.185   1.00 44.07  ? 57  ASP C N   1 
ATOM   3149 C  CA  . ASP C 1 57  ? 20.652  -54.824 3.455   1.00 44.36  ? 57  ASP C CA  1 
ATOM   3150 C  C   . ASP C 1 57  ? 20.691  -55.124 4.953   1.00 44.59  ? 57  ASP C C   1 
ATOM   3151 O  O   . ASP C 1 57  ? 20.451  -56.263 5.370   1.00 46.65  ? 57  ASP C O   1 
ATOM   3152 C  CB  . ASP C 1 57  ? 22.084  -54.765 2.904   1.00 38.40  ? 57  ASP C CB  1 
ATOM   3153 C  CG  . ASP C 1 57  ? 22.151  -54.601 1.373   1.00 50.19  ? 57  ASP C CG  1 
ATOM   3154 O  OD1 . ASP C 1 57  ? 21.124  -54.768 0.677   1.00 49.60  ? 57  ASP C OD1 1 
ATOM   3155 O  OD2 . ASP C 1 57  ? 23.254  -54.284 0.861   1.00 47.94  ? 57  ASP C OD2 1 
ATOM   3156 N  N   . GLU C 1 58  ? 21.021  -54.119 5.777   1.00 40.13  ? 58  GLU C N   1 
ATOM   3157 C  CA  . GLU C 1 58  ? 21.029  -54.302 7.229   1.00 42.83  ? 58  GLU C CA  1 
ATOM   3158 C  C   . GLU C 1 58  ? 19.704  -54.891 7.709   1.00 48.82  ? 58  GLU C C   1 
ATOM   3159 O  O   . GLU C 1 58  ? 19.673  -55.962 8.320   1.00 45.35  ? 58  GLU C O   1 
ATOM   3160 C  CB  . GLU C 1 58  ? 21.292  -52.968 7.938   1.00 49.61  ? 58  GLU C CB  1 
ATOM   3161 C  CG  . GLU C 1 58  ? 22.760  -52.609 8.201   1.00 62.10  ? 58  GLU C CG  1 
ATOM   3162 C  CD  . GLU C 1 58  ? 22.941  -51.164 8.718   1.00 73.36  ? 58  GLU C CD  1 
ATOM   3163 O  OE1 . GLU C 1 58  ? 21.931  -50.488 9.034   1.00 69.80  ? 58  GLU C OE1 1 
ATOM   3164 O  OE2 . GLU C 1 58  ? 24.099  -50.693 8.784   1.00 80.19  ? 58  GLU C OE2 1 
ATOM   3165 N  N   . GLU C 1 59  ? 18.589  -54.206 7.403   1.00 43.07  ? 59  GLU C N   1 
ATOM   3166 C  CA  . GLU C 1 59  ? 17.283  -54.644 7.881   1.00 45.23  ? 59  GLU C CA  1 
ATOM   3167 C  C   . GLU C 1 59  ? 16.947  -56.051 7.394   1.00 45.40  ? 59  GLU C C   1 
ATOM   3168 O  O   . GLU C 1 59  ? 16.385  -56.859 8.147   1.00 40.48  ? 59  GLU C O   1 
ATOM   3169 C  CB  . GLU C 1 59  ? 16.196  -53.651 7.451   1.00 41.35  ? 59  GLU C CB  1 
ATOM   3170 C  CG  . GLU C 1 59  ? 16.420  -52.237 7.955   1.00 42.83  ? 59  GLU C CG  1 
ATOM   3171 C  CD  . GLU C 1 59  ? 16.482  -52.184 9.465   1.00 54.55  ? 59  GLU C CD  1 
ATOM   3172 O  OE1 . GLU C 1 59  ? 15.725  -52.951 10.095  1.00 53.40  ? 59  GLU C OE1 1 
ATOM   3173 O  OE2 . GLU C 1 59  ? 17.300  -51.401 10.012  1.00 61.65  ? 59  GLU C OE2 1 
ATOM   3174 N  N   . ARG C 1 60  ? 17.281  -56.369 6.143   1.00 34.92  ? 60  ARG C N   1 
ATOM   3175 C  CA  . ARG C 1 60  ? 17.044  -57.731 5.690   1.00 38.77  ? 60  ARG C CA  1 
ATOM   3176 C  C   . ARG C 1 60  ? 17.854  -58.730 6.513   1.00 42.95  ? 60  ARG C C   1 
ATOM   3177 O  O   . ARG C 1 60  ? 17.409  -59.869 6.708   1.00 41.76  ? 60  ARG C O   1 
ATOM   3178 C  CB  . ARG C 1 60  ? 17.361  -57.855 4.204   1.00 35.76  ? 60  ARG C CB  1 
ATOM   3179 C  CG  . ARG C 1 60  ? 17.023  -59.195 3.578   1.00 36.23  ? 60  ARG C CG  1 
ATOM   3180 C  CD  . ARG C 1 60  ? 17.165  -59.087 2.072   1.00 43.31  ? 60  ARG C CD  1 
ATOM   3181 N  NE  . ARG C 1 60  ? 16.972  -60.352 1.365   1.00 49.47  ? 60  ARG C NE  1 
ATOM   3182 C  CZ  . ARG C 1 60  ? 17.951  -61.203 1.068   1.00 52.92  ? 60  ARG C CZ  1 
ATOM   3183 N  NH1 . ARG C 1 60  ? 17.692  -62.336 0.401   1.00 45.91  ? 60  ARG C NH1 1 
ATOM   3184 N  NH2 . ARG C 1 60  ? 19.190  -60.924 1.452   1.00 51.63  ? 60  ARG C NH2 1 
ATOM   3185 N  N   . GLU C 1 61  ? 19.021  -58.314 7.028   1.00 40.38  ? 61  GLU C N   1 
ATOM   3186 C  CA  . GLU C 1 61  ? 19.834  -59.193 7.870   1.00 47.48  ? 61  GLU C CA  1 
ATOM   3187 C  C   . GLU C 1 61  ? 19.225  -59.354 9.254   1.00 47.26  ? 61  GLU C C   1 
ATOM   3188 O  O   . GLU C 1 61  ? 19.228  -60.461 9.811   1.00 49.18  ? 61  GLU C O   1 
ATOM   3189 C  CB  . GLU C 1 61  ? 21.270  -58.666 7.989   1.00 46.89  ? 61  GLU C CB  1 
ATOM   3190 C  CG  . GLU C 1 61  ? 22.122  -58.867 6.731   1.00 51.06  ? 61  GLU C CG  1 
ATOM   3191 C  CD  . GLU C 1 61  ? 22.287  -60.341 6.350   1.00 62.12  ? 61  GLU C CD  1 
ATOM   3192 O  OE1 . GLU C 1 61  ? 22.519  -61.178 7.259   1.00 63.18  ? 61  GLU C OE1 1 
ATOM   3193 O  OE2 . GLU C 1 61  ? 22.182  -60.662 5.141   1.00 64.31  ? 61  GLU C OE2 1 
ATOM   3194 N  N   . HIS C 1 62  ? 18.698  -58.267 9.828   1.00 46.20  ? 62  HIS C N   1 
ATOM   3195 C  CA  . HIS C 1 62  ? 18.018  -58.378 11.113  1.00 49.50  ? 62  HIS C CA  1 
ATOM   3196 C  C   . HIS C 1 62  ? 16.849  -59.345 11.030  1.00 46.40  ? 62  HIS C C   1 
ATOM   3197 O  O   . HIS C 1 62  ? 16.661  -60.172 11.929  1.00 47.70  ? 62  HIS C O   1 
ATOM   3198 C  CB  . HIS C 1 62  ? 17.535  -57.012 11.585  1.00 53.00  ? 62  HIS C CB  1 
ATOM   3199 C  CG  . HIS C 1 62  ? 18.634  -56.115 12.042  1.00 63.97  ? 62  HIS C CG  1 
ATOM   3200 N  ND1 . HIS C 1 62  ? 18.731  -54.797 11.647  1.00 67.73  ? 62  HIS C ND1 1 
ATOM   3201 C  CD2 . HIS C 1 62  ? 19.685  -56.341 12.865  1.00 71.62  ? 62  HIS C CD2 1 
ATOM   3202 C  CE1 . HIS C 1 62  ? 19.797  -54.251 12.205  1.00 72.75  ? 62  HIS C CE1 1 
ATOM   3203 N  NE2 . HIS C 1 62  ? 20.395  -55.167 12.947  1.00 78.53  ? 62  HIS C NE2 1 
ATOM   3204 N  N   . ALA C 1 63  ? 16.047  -59.248 9.962   1.00 42.61  ? 63  ALA C N   1 
ATOM   3205 C  CA  . ALA C 1 63  ? 14.939  -60.179 9.785   1.00 44.81  ? 63  ALA C CA  1 
ATOM   3206 C  C   . ALA C 1 63  ? 15.438  -61.615 9.828   1.00 45.30  ? 63  ALA C C   1 
ATOM   3207 O  O   . ALA C 1 63  ? 14.923  -62.444 10.583  1.00 44.08  ? 63  ALA C O   1 
ATOM   3208 C  CB  . ALA C 1 63  ? 14.209  -59.902 8.472   1.00 36.55  ? 63  ALA C CB  1 
ATOM   3209 N  N   . GLN C 1 64  ? 16.483  -61.913 9.059   1.00 43.82  ? 64  GLN C N   1 
ATOM   3210 C  CA  . GLN C 1 64  ? 17.008  -63.272 9.048   1.00 47.06  ? 64  GLN C CA  1 
ATOM   3211 C  C   . GLN C 1 64  ? 17.517  -63.694 10.422  1.00 44.76  ? 64  GLN C C   1 
ATOM   3212 O  O   . GLN C 1 64  ? 17.416  -64.873 10.775  1.00 41.38  ? 64  GLN C O   1 
ATOM   3213 C  CB  . GLN C 1 64  ? 18.105  -63.399 7.994   1.00 37.73  ? 64  GLN C CB  1 
ATOM   3214 C  CG  . GLN C 1 64  ? 17.559  -63.167 6.626   1.00 44.63  ? 64  GLN C CG  1 
ATOM   3215 C  CD  . GLN C 1 64  ? 18.574  -63.385 5.545   1.00 43.99  ? 64  GLN C CD  1 
ATOM   3216 O  OE1 . GLN C 1 64  ? 19.057  -64.501 5.348   1.00 47.76  ? 64  GLN C OE1 1 
ATOM   3217 N  NE2 . GLN C 1 64  ? 18.906  -62.317 4.824   1.00 43.47  ? 64  GLN C NE2 1 
ATOM   3218 N  N   . THR C 1 65  ? 18.055  -62.757 11.210  1.00 41.20  ? 65  THR C N   1 
ATOM   3219 C  CA  . THR C 1 65  ? 18.459  -63.085 12.575  1.00 40.88  ? 65  THR C CA  1 
ATOM   3220 C  C   . THR C 1 65  ? 17.268  -63.585 13.389  1.00 40.88  ? 65  THR C C   1 
ATOM   3221 O  O   . THR C 1 65  ? 17.354  -64.623 14.061  1.00 41.23  ? 65  THR C O   1 
ATOM   3222 C  CB  . THR C 1 65  ? 19.109  -61.870 13.237  1.00 42.31  ? 65  THR C CB  1 
ATOM   3223 O  OG1 . THR C 1 65  ? 20.317  -61.551 12.544  1.00 46.09  ? 65  THR C OG1 1 
ATOM   3224 C  CG2 . THR C 1 65  ? 19.446  -62.158 14.676  1.00 40.56  ? 65  THR C CG2 1 
ATOM   3225 N  N   . PHE C 1 66  ? 16.132  -62.884 13.307  1.00 37.49  ? 66  PHE C N   1 
ATOM   3226 C  CA  . PHE C 1 66  ? 14.930  -63.344 14.003  1.00 42.10  ? 66  PHE C CA  1 
ATOM   3227 C  C   . PHE C 1 66  ? 14.377  -64.633 13.403  1.00 42.68  ? 66  PHE C C   1 
ATOM   3228 O  O   . PHE C 1 66  ? 13.817  -65.458 14.135  1.00 42.72  ? 66  PHE C O   1 
ATOM   3229 C  CB  . PHE C 1 66  ? 13.857  -62.259 14.005  1.00 44.18  ? 66  PHE C CB  1 
ATOM   3230 C  CG  . PHE C 1 66  ? 14.195  -61.097 14.894  1.00 48.97  ? 66  PHE C CG  1 
ATOM   3231 C  CD1 . PHE C 1 66  ? 14.352  -61.280 16.257  1.00 52.63  ? 66  PHE C CD1 1 
ATOM   3232 C  CD2 . PHE C 1 66  ? 14.381  -59.831 14.371  1.00 52.47  ? 66  PHE C CD2 1 
ATOM   3233 C  CE1 . PHE C 1 66  ? 14.682  -60.224 17.076  1.00 56.06  ? 66  PHE C CE1 1 
ATOM   3234 C  CE2 . PHE C 1 66  ? 14.712  -58.763 15.194  1.00 60.45  ? 66  PHE C CE2 1 
ATOM   3235 C  CZ  . PHE C 1 66  ? 14.863  -58.963 16.544  1.00 60.33  ? 66  PHE C CZ  1 
ATOM   3236 N  N   . MET C 1 67  ? 14.537  -64.844 12.092  1.00 41.25  ? 67  MET C N   1 
ATOM   3237 C  CA  . MET C 1 67  ? 14.136  -66.123 11.507  1.00 40.30  ? 67  MET C CA  1 
ATOM   3238 C  C   . MET C 1 67  ? 14.996  -67.274 12.041  1.00 41.53  ? 67  MET C C   1 
ATOM   3239 O  O   . MET C 1 67  ? 14.472  -68.356 12.330  1.00 42.60  ? 67  MET C O   1 
ATOM   3240 C  CB  . MET C 1 67  ? 14.209  -66.059 9.981   1.00 36.29  ? 67  MET C CB  1 
ATOM   3241 C  CG  . MET C 1 67  ? 13.220  -65.097 9.320   1.00 44.91  ? 67  MET C CG  1 
ATOM   3242 S  SD  . MET C 1 67  ? 13.521  -64.846 7.533   1.00 40.59  ? 67  MET C SD  1 
ATOM   3243 C  CE  . MET C 1 67  ? 12.919  -66.386 6.822   1.00 38.13  ? 67  MET C CE  1 
ATOM   3244 N  N   . LYS C 1 68  ? 16.317  -67.063 12.176  1.00 39.62  ? 68  LYS C N   1 
ATOM   3245 C  CA  . LYS C 1 68  ? 17.189  -68.110 12.715  1.00 49.06  ? 68  LYS C CA  1 
ATOM   3246 C  C   . LYS C 1 68  ? 16.869  -68.383 14.178  1.00 46.84  ? 68  LYS C C   1 
ATOM   3247 O  O   . LYS C 1 68  ? 16.908  -69.536 14.619  1.00 46.32  ? 68  LYS C O   1 
ATOM   3248 C  CB  . LYS C 1 68  ? 18.684  -67.751 12.557  1.00 41.73  ? 68  LYS C CB  1 
ATOM   3249 C  CG  . LYS C 1 68  ? 19.101  -67.292 11.164  1.00 55.32  ? 68  LYS C CG  1 
ATOM   3250 C  CD  . LYS C 1 68  ? 20.596  -67.407 10.868  1.00 64.33  ? 68  LYS C CD  1 
ATOM   3251 C  CE  . LYS C 1 68  ? 21.261  -66.009 10.781  1.00 66.93  ? 68  LYS C CE  1 
ATOM   3252 N  NZ  . LYS C 1 68  ? 21.604  -65.592 9.376   1.00 64.52  ? 68  LYS C NZ  1 
ATOM   3253 N  N   . TYR C 1 69  ? 16.553  -67.336 14.946  1.00 48.87  ? 69  TYR C N   1 
ATOM   3254 C  CA  . TYR C 1 69  ? 16.201  -67.549 16.343  1.00 46.13  ? 69  TYR C CA  1 
ATOM   3255 C  C   . TYR C 1 69  ? 14.890  -68.316 16.458  1.00 49.26  ? 69  TYR C C   1 
ATOM   3256 O  O   . TYR C 1 69  ? 14.733  -69.158 17.351  1.00 47.61  ? 69  TYR C O   1 
ATOM   3257 C  CB  . TYR C 1 69  ? 16.119  -66.214 17.082  1.00 44.68  ? 69  TYR C CB  1 
ATOM   3258 C  CG  . TYR C 1 69  ? 15.806  -66.386 18.544  1.00 46.76  ? 69  TYR C CG  1 
ATOM   3259 C  CD1 . TYR C 1 69  ? 16.787  -66.818 19.435  1.00 55.76  ? 69  TYR C CD1 1 
ATOM   3260 C  CD2 . TYR C 1 69  ? 14.525  -66.161 19.032  1.00 45.04  ? 69  TYR C CD2 1 
ATOM   3261 C  CE1 . TYR C 1 69  ? 16.502  -67.014 20.777  1.00 56.87  ? 69  TYR C CE1 1 
ATOM   3262 C  CE2 . TYR C 1 69  ? 14.222  -66.351 20.376  1.00 51.63  ? 69  TYR C CE2 1 
ATOM   3263 C  CZ  . TYR C 1 69  ? 15.221  -66.774 21.242  1.00 58.17  ? 69  TYR C CZ  1 
ATOM   3264 O  OH  . TYR C 1 69  ? 14.946  -66.965 22.576  1.00 61.68  ? 69  TYR C OH  1 
ATOM   3265 N  N   . GLN C 1 70  ? 13.943  -68.047 15.559  1.00 46.32  ? 70  GLN C N   1 
ATOM   3266 C  CA  . GLN C 1 70  ? 12.695  -68.797 15.559  1.00 45.09  ? 70  GLN C CA  1 
ATOM   3267 C  C   . GLN C 1 70  ? 12.970  -70.280 15.387  1.00 43.65  ? 70  GLN C C   1 
ATOM   3268 O  O   . GLN C 1 70  ? 12.550  -71.105 16.201  1.00 46.37  ? 70  GLN C O   1 
ATOM   3269 C  CB  . GLN C 1 70  ? 11.776  -68.294 14.448  1.00 48.60  ? 70  GLN C CB  1 
ATOM   3270 C  CG  . GLN C 1 70  ? 10.396  -68.953 14.433  1.00 50.35  ? 70  GLN C CG  1 
ATOM   3271 C  CD  . GLN C 1 70  ? 9.414   -68.253 15.354  1.00 52.47  ? 70  GLN C CD  1 
ATOM   3272 O  OE1 . GLN C 1 70  ? 9.496   -68.397 16.570  1.00 50.02  ? 70  GLN C OE1 1 
ATOM   3273 N  NE2 . GLN C 1 70  ? 8.489   -67.475 14.777  1.00 48.00  ? 70  GLN C NE2 1 
ATOM   3274 N  N   . ASN C 1 71  ? 13.698  -70.631 14.331  1.00 43.44  ? 71  ASN C N   1 
ATOM   3275 C  CA  . ASN C 1 71  ? 14.061  -72.023 14.094  1.00 44.89  ? 71  ASN C CA  1 
ATOM   3276 C  C   . ASN C 1 71  ? 14.792  -72.632 15.280  1.00 52.07  ? 71  ASN C C   1 
ATOM   3277 O  O   . ASN C 1 71  ? 14.573  -73.799 15.629  1.00 50.75  ? 71  ASN C O   1 
ATOM   3278 C  CB  . ASN C 1 71  ? 14.939  -72.102 12.864  1.00 38.33  ? 71  ASN C CB  1 
ATOM   3279 C  CG  . ASN C 1 71  ? 14.141  -72.202 11.626  1.00 44.12  ? 71  ASN C CG  1 
ATOM   3280 O  OD1 . ASN C 1 71  ? 12.980  -72.632 11.666  1.00 44.54  ? 71  ASN C OD1 1 
ATOM   3281 N  ND2 . ASN C 1 71  ? 14.737  -71.809 10.502  1.00 38.56  ? 71  ASN C ND2 1 
ATOM   3282 N  N   . CYS C 1 72  ? 15.697  -71.864 15.883  1.00 48.02  ? 72  CYS C N   1 
ATOM   3283 C  CA  . CYS C 1 72  ? 16.560  -72.384 16.923  1.00 56.38  ? 72  CYS C CA  1 
ATOM   3284 C  C   . CYS C 1 72  ? 15.793  -72.612 18.226  1.00 55.00  ? 72  CYS C C   1 
ATOM   3285 O  O   . CYS C 1 72  ? 16.177  -73.477 19.020  1.00 53.69  ? 72  CYS C O   1 
ATOM   3286 C  CB  . CYS C 1 72  ? 17.748  -71.427 17.068  1.00 56.33  ? 72  CYS C CB  1 
ATOM   3287 S  SG  . CYS C 1 72  ? 18.621  -71.429 18.606  1.00 88.25  ? 72  CYS C SG  1 
ATOM   3288 N  N   . ARG C 1 73  ? 14.687  -71.907 18.431  1.00 46.77  ? 73  ARG C N   1 
ATOM   3289 C  CA  . ARG C 1 73  ? 13.790  -72.212 19.524  1.00 40.70  ? 73  ARG C CA  1 
ATOM   3290 C  C   . ARG C 1 73  ? 12.770  -73.274 19.160  1.00 47.77  ? 73  ARG C C   1 
ATOM   3291 O  O   . ARG C 1 73  ? 12.011  -73.708 20.032  1.00 52.92  ? 73  ARG C O   1 
ATOM   3292 C  CB  . ARG C 1 73  ? 13.063  -70.951 19.990  1.00 52.83  ? 73  ARG C CB  1 
ATOM   3293 C  CG  . ARG C 1 73  ? 13.928  -69.986 20.787  1.00 56.58  ? 73  ARG C CG  1 
ATOM   3294 C  CD  . ARG C 1 73  ? 14.682  -70.664 21.941  1.00 57.29  ? 73  ARG C CD  1 
ATOM   3295 N  NE  . ARG C 1 73  ? 13.831  -71.055 23.067  1.00 64.01  ? 73  ARG C NE  1 
ATOM   3296 C  CZ  . ARG C 1 73  ? 13.334  -70.209 23.970  1.00 62.61  ? 73  ARG C CZ  1 
ATOM   3297 N  NH1 . ARG C 1 73  ? 13.576  -68.909 23.877  1.00 63.45  ? 73  ARG C NH1 1 
ATOM   3298 N  NH2 . ARG C 1 73  ? 12.588  -70.660 24.966  1.00 60.93  ? 73  ARG C NH2 1 
ATOM   3299 N  N   . GLY C 1 74  ? 12.744  -73.728 17.911  1.00 48.50  ? 74  GLY C N   1 
ATOM   3300 C  CA  . GLY C 1 74  ? 11.760  -74.706 17.502  1.00 43.25  ? 74  GLY C CA  1 
ATOM   3301 C  C   . GLY C 1 74  ? 10.374  -74.155 17.227  1.00 51.14  ? 74  GLY C C   1 
ATOM   3302 O  O   . GLY C 1 74  ? 9.451   -74.947 16.969  1.00 50.76  ? 74  GLY C O   1 
ATOM   3303 N  N   . GLY C 1 75  ? 10.185  -72.838 17.293  1.00 39.56  ? 75  GLY C N   1 
ATOM   3304 C  CA  . GLY C 1 75  ? 8.994   -72.235 16.742  1.00 44.92  ? 75  GLY C CA  1 
ATOM   3305 C  C   . GLY C 1 75  ? 9.024   -72.312 15.224  1.00 50.99  ? 75  GLY C C   1 
ATOM   3306 O  O   . GLY C 1 75  ? 9.987   -72.770 14.601  1.00 47.98  ? 75  GLY C O   1 
ATOM   3307 N  N   . ARG C 1 76  ? 7.941   -71.850 14.605  1.00 43.76  ? 76  ARG C N   1 
ATOM   3308 C  CA  . ARG C 1 76  ? 7.865   -71.944 13.158  1.00 48.32  ? 76  ARG C CA  1 
ATOM   3309 C  C   . ARG C 1 76  ? 7.585   -70.581 12.546  1.00 50.88  ? 76  ARG C C   1 
ATOM   3310 O  O   . ARG C 1 76  ? 6.664   -69.867 12.968  1.00 50.58  ? 76  ARG C O   1 
ATOM   3311 C  CB  . ARG C 1 76  ? 6.849   -73.005 12.728  1.00 49.60  ? 76  ARG C CB  1 
ATOM   3312 C  CG  . ARG C 1 76  ? 7.196   -74.388 13.354  1.00 50.25  ? 76  ARG C CG  1 
ATOM   3313 C  CD  . ARG C 1 76  ? 7.826   -75.361 12.355  1.00 52.96  ? 76  ARG C CD  1 
ATOM   3314 N  NE  . ARG C 1 76  ? 8.559   -76.464 12.994  1.00 53.10  ? 76  ARG C NE  1 
ATOM   3315 C  CZ  . ARG C 1 76  ? 9.745   -76.363 13.605  1.00 61.05  ? 76  ARG C CZ  1 
ATOM   3316 N  NH1 . ARG C 1 76  ? 10.391  -75.199 13.660  1.00 60.33  ? 76  ARG C NH1 1 
ATOM   3317 N  NH2 . ARG C 1 76  ? 10.302  -77.442 14.157  1.00 58.82  ? 76  ARG C NH2 1 
ATOM   3318 N  N   . ILE C 1 77  ? 8.424   -70.231 11.562  1.00 47.48  ? 77  ILE C N   1 
ATOM   3319 C  CA  . ILE C 1 77  ? 8.383   -68.926 10.911  1.00 54.38  ? 77  ILE C CA  1 
ATOM   3320 C  C   . ILE C 1 77  ? 7.072   -68.796 10.147  1.00 48.59  ? 77  ILE C C   1 
ATOM   3321 O  O   . ILE C 1 77  ? 6.676   -69.711 9.421   1.00 39.55  ? 77  ILE C O   1 
ATOM   3322 C  CB  . ILE C 1 77  ? 9.591   -68.760 9.968   1.00 48.36  ? 77  ILE C CB  1 
ATOM   3323 C  CG1 . ILE C 1 77  ? 10.892  -68.771 10.751  1.00 44.49  ? 77  ILE C CG1 1 
ATOM   3324 C  CG2 . ILE C 1 77  ? 9.455   -67.498 9.102   1.00 50.14  ? 77  ILE C CG2 1 
ATOM   3325 C  CD1 . ILE C 1 77  ? 11.973  -69.492 10.027  1.00 36.28  ? 77  ILE C CD1 1 
ATOM   3326 N  N   . VAL C 1 78  ? 6.392   -67.660 10.308  1.00 55.28  ? 78  VAL C N   1 
ATOM   3327 C  CA  . VAL C 1 78  ? 5.218   -67.307 9.511   1.00 56.32  ? 78  VAL C CA  1 
ATOM   3328 C  C   . VAL C 1 78  ? 5.462   -65.940 8.867   1.00 50.02  ? 78  VAL C C   1 
ATOM   3329 O  O   . VAL C 1 78  ? 5.379   -64.890 9.524   1.00 57.66  ? 78  VAL C O   1 
ATOM   3330 C  CB  . VAL C 1 78  ? 3.935   -67.320 10.332  1.00 51.90  ? 78  VAL C CB  1 
ATOM   3331 C  CG1 . VAL C 1 78  ? 2.729   -67.276 9.374   1.00 51.26  ? 78  VAL C CG1 1 
ATOM   3332 C  CG2 . VAL C 1 78  ? 3.857   -68.610 11.141  1.00 43.81  ? 78  VAL C CG2 1 
ATOM   3333 N  N   . LEU C 1 79  ? 5.781   -65.966 7.587   1.00 43.69  ? 79  LEU C N   1 
ATOM   3334 C  CA  . LEU C 1 79  ? 6.039   -64.778 6.789   1.00 61.14  ? 79  LEU C CA  1 
ATOM   3335 C  C   . LEU C 1 79  ? 4.741   -64.345 6.115   1.00 54.26  ? 79  LEU C C   1 
ATOM   3336 O  O   . LEU C 1 79  ? 4.008   -65.177 5.578   1.00 48.78  ? 79  LEU C O   1 
ATOM   3337 C  CB  . LEU C 1 79  ? 7.093   -65.082 5.722   1.00 49.36  ? 79  LEU C CB  1 
ATOM   3338 C  CG  . LEU C 1 79  ? 8.411   -65.735 6.087   1.00 48.04  ? 79  LEU C CG  1 
ATOM   3339 C  CD1 . LEU C 1 79  ? 9.022   -66.324 4.839   1.00 33.50  ? 79  LEU C CD1 1 
ATOM   3340 C  CD2 . LEU C 1 79  ? 9.281   -64.639 6.658   1.00 42.35  ? 79  LEU C CD2 1 
ATOM   3341 N  N   . GLN C 1 80  ? 4.454   -63.059 6.137   1.00 53.34  ? 80  GLN C N   1 
ATOM   3342 C  CA  . GLN C 1 80  ? 3.252   -62.587 5.487   1.00 46.08  ? 80  GLN C CA  1 
ATOM   3343 C  C   . GLN C 1 80  ? 3.633   -61.774 4.268   1.00 47.06  ? 80  GLN C C   1 
ATOM   3344 O  O   . GLN C 1 80  ? 4.818   -61.671 3.917   1.00 46.07  ? 80  GLN C O   1 
ATOM   3345 C  CB  . GLN C 1 80  ? 2.417   -61.784 6.473   1.00 47.70  ? 80  GLN C CB  1 
ATOM   3346 C  CG  . GLN C 1 80  ? 1.620   -62.674 7.357   1.00 59.96  ? 80  GLN C CG  1 
ATOM   3347 C  CD  . GLN C 1 80  ? 2.318   -62.946 8.638   1.00 72.26  ? 80  GLN C CD  1 
ATOM   3348 O  OE1 . GLN C 1 80  ? 2.285   -64.069 9.144   1.00 77.40  ? 80  GLN C OE1 1 
ATOM   3349 N  NE2 . GLN C 1 80  ? 2.975   -61.919 9.187   1.00 71.61  ? 80  GLN C NE2 1 
ATOM   3350 N  N   . GLN C 1 81  ? 2.620   -61.195 3.614   1.00 44.65  ? 81  GLN C N   1 
ATOM   3351 C  CA  . GLN C 1 81  ? 2.889   -60.182 2.603   1.00 44.08  ? 81  GLN C CA  1 
ATOM   3352 C  C   . GLN C 1 81  ? 3.771   -59.098 3.203   1.00 40.65  ? 81  GLN C C   1 
ATOM   3353 O  O   . GLN C 1 81  ? 3.780   -58.880 4.419   1.00 39.79  ? 81  GLN C O   1 
ATOM   3354 C  CB  . GLN C 1 81  ? 1.595   -59.550 2.058   1.00 41.62  ? 81  GLN C CB  1 
ATOM   3355 C  CG  . GLN C 1 81  ? 0.747   -58.761 3.074   1.00 43.96  ? 81  GLN C CG  1 
ATOM   3356 C  CD  . GLN C 1 81  ? -0.060  -59.656 4.053   1.00 49.15  ? 81  GLN C CD  1 
ATOM   3357 O  OE1 . GLN C 1 81  ? 0.098   -60.885 4.095   1.00 48.83  ? 81  GLN C OE1 1 
ATOM   3358 N  NE2 . GLN C 1 81  ? -0.939  -59.028 4.829   1.00 45.37  ? 81  GLN C NE2 1 
ATOM   3359 N  N   . ILE C 1 82  ? 4.548   -58.450 2.350   1.00 30.75  ? 82  ILE C N   1 
ATOM   3360 C  CA  . ILE C 1 82  ? 5.310   -57.274 2.735   1.00 34.72  ? 82  ILE C CA  1 
ATOM   3361 C  C   . ILE C 1 82  ? 4.628   -56.090 2.067   1.00 38.62  ? 82  ILE C C   1 
ATOM   3362 O  O   . ILE C 1 82  ? 4.577   -56.014 0.830   1.00 37.15  ? 82  ILE C O   1 
ATOM   3363 C  CB  . ILE C 1 82  ? 6.788   -57.383 2.330   1.00 36.17  ? 82  ILE C CB  1 
ATOM   3364 C  CG1 . ILE C 1 82  ? 7.399   -58.706 2.841   1.00 32.76  ? 82  ILE C CG1 1 
ATOM   3365 C  CG2 . ILE C 1 82  ? 7.562   -56.188 2.865   1.00 33.74  ? 82  ILE C CG2 1 
ATOM   3366 C  CD1 . ILE C 1 82  ? 8.667   -59.120 2.121   1.00 30.42  ? 82  ILE C CD1 1 
ATOM   3367 N  N   . ALA C 1 83  ? 4.074   -55.198 2.892   1.00 34.47  ? 83  ALA C N   1 
ATOM   3368 C  CA  . ALA C 1 83  ? 3.368   -54.005 2.429   1.00 37.01  ? 83  ALA C CA  1 
ATOM   3369 C  C   . ALA C 1 83  ? 4.217   -53.182 1.468   1.00 35.71  ? 83  ALA C C   1 
ATOM   3370 O  O   . ALA C 1 83  ? 5.435   -53.080 1.621   1.00 45.64  ? 83  ALA C O   1 
ATOM   3371 C  CB  . ALA C 1 83  ? 2.996   -53.127 3.625   1.00 30.53  ? 83  ALA C CB  1 
ATOM   3372 N  N   . ALA C 1 84  ? 3.565   -52.573 0.482   1.00 37.62  ? 84  ALA C N   1 
ATOM   3373 C  CA  . ALA C 1 84  ? 4.240   -51.567 -0.324  1.00 43.44  ? 84  ALA C CA  1 
ATOM   3374 C  C   . ALA C 1 84  ? 4.675   -50.417 0.578   1.00 38.41  ? 84  ALA C C   1 
ATOM   3375 O  O   . ALA C 1 84  ? 4.010   -50.112 1.572   1.00 38.60  ? 84  ALA C O   1 
ATOM   3376 C  CB  . ALA C 1 84  ? 3.333   -51.031 -1.435  1.00 34.26  ? 84  ALA C CB  1 
ATOM   3377 N  N   . PRO C 1 85  ? 5.801   -49.790 0.277   1.00 36.89  ? 85  PRO C N   1 
ATOM   3378 C  CA  . PRO C 1 85  ? 6.191   -48.588 1.019   1.00 44.87  ? 85  PRO C CA  1 
ATOM   3379 C  C   . PRO C 1 85  ? 5.094   -47.527 0.971   1.00 45.52  ? 85  PRO C C   1 
ATOM   3380 O  O   . PRO C 1 85  ? 4.390   -47.377 -0.029  1.00 46.35  ? 85  PRO C O   1 
ATOM   3381 C  CB  . PRO C 1 85  ? 7.461   -48.130 0.298   1.00 39.52  ? 85  PRO C CB  1 
ATOM   3382 C  CG  . PRO C 1 85  ? 8.007   -49.376 -0.301  1.00 36.18  ? 85  PRO C CG  1 
ATOM   3383 C  CD  . PRO C 1 85  ? 6.825   -50.211 -0.689  1.00 36.70  ? 85  PRO C CD  1 
ATOM   3384 N  N   . SER C 1 86  ? 4.951   -46.803 2.082   1.00 48.33  ? 86  SER C N   1 
ATOM   3385 C  CA  . SER C 1 86  ? 3.918   -45.774 2.206   1.00 55.66  ? 86  SER C CA  1 
ATOM   3386 C  C   . SER C 1 86  ? 4.036   -44.703 1.124   1.00 55.41  ? 86  SER C C   1 
ATOM   3387 O  O   . SER C 1 86  ? 3.021   -44.147 0.689   1.00 56.04  ? 86  SER C O   1 
ATOM   3388 C  CB  . SER C 1 86  ? 4.001   -45.148 3.601   1.00 54.97  ? 86  SER C CB  1 
ATOM   3389 O  OG  . SER C 1 86  ? 5.356   -45.072 4.033   1.00 60.83  ? 86  SER C OG  1 
ATOM   3390 N  N   . MET C 1 87  ? 5.251   -44.427 0.659   1.00 57.87  ? 87  MET C N   1 
ATOM   3391 C  CA  . MET C 1 87  ? 5.529   -43.427 -0.360  1.00 49.58  ? 87  MET C CA  1 
ATOM   3392 C  C   . MET C 1 87  ? 6.224   -44.049 -1.565  1.00 55.23  ? 87  MET C C   1 
ATOM   3393 O  O   . MET C 1 87  ? 6.836   -45.123 -1.494  1.00 53.97  ? 87  MET C O   1 
ATOM   3394 C  CB  . MET C 1 87  ? 6.427   -42.314 0.194   1.00 52.99  ? 87  MET C CB  1 
ATOM   3395 C  CG  . MET C 1 87  ? 5.890   -41.609 1.426   1.00 59.49  ? 87  MET C CG  1 
ATOM   3396 S  SD  . MET C 1 87  ? 4.588   -40.448 1.002   1.00 67.61  ? 87  MET C SD  1 
ATOM   3397 C  CE  . MET C 1 87  ? 5.187   -39.732 -0.522  1.00 56.72  ? 87  MET C CE  1 
ATOM   3398 N  N   . ARG C 1 88  ? 6.144   -43.317 -2.671  1.00 55.49  ? 88  ARG C N   1 
ATOM   3399 C  CA  . ARG C 1 88  ? 6.956   -43.523 -3.860  1.00 51.81  ? 88  ARG C CA  1 
ATOM   3400 C  C   . ARG C 1 88  ? 8.039   -42.488 -4.047  1.00 53.00  ? 88  ARG C C   1 
ATOM   3401 O  O   . ARG C 1 88  ? 9.072   -42.787 -4.650  1.00 54.99  ? 88  ARG C O   1 
ATOM   3402 C  CB  . ARG C 1 88  ? 6.082   -43.477 -5.107  1.00 63.25  ? 88  ARG C CB  1 
ATOM   3403 C  CG  . ARG C 1 88  ? 5.256   -44.639 -5.138  1.00 63.56  ? 88  ARG C CG  1 
ATOM   3404 C  CD  . ARG C 1 88  ? 6.172   -45.742 -5.568  1.00 63.89  ? 88  ARG C CD  1 
ATOM   3405 N  NE  . ARG C 1 88  ? 5.412   -46.928 -5.380  1.00 57.83  ? 88  ARG C NE  1 
ATOM   3406 C  CZ  . ARG C 1 88  ? 5.427   -47.565 -4.232  1.00 67.04  ? 88  ARG C CZ  1 
ATOM   3407 N  NH1 . ARG C 1 88  ? 6.221   -47.128 -3.263  1.00 65.80  ? 88  ARG C NH1 1 
ATOM   3408 N  NH2 . ARG C 1 88  ? 4.668   -48.625 -4.054  1.00 63.80  ? 88  ARG C NH2 1 
ATOM   3409 N  N   . GLU C 1 89  ? 7.789   -41.270 -3.606  1.00 51.36  ? 89  GLU C N   1 
ATOM   3410 C  CA  . GLU C 1 89  ? 8.661   -40.130 -3.806  1.00 55.16  ? 89  GLU C CA  1 
ATOM   3411 C  C   . GLU C 1 89  ? 8.916   -39.607 -2.409  1.00 52.52  ? 89  GLU C C   1 
ATOM   3412 O  O   . GLU C 1 89  ? 7.980   -39.230 -1.696  1.00 48.70  ? 89  GLU C O   1 
ATOM   3413 C  CB  . GLU C 1 89  ? 8.001   -39.085 -4.701  1.00 52.88  ? 89  GLU C CB  1 
ATOM   3414 C  CG  . GLU C 1 89  ? 7.391   -39.707 -5.937  1.00 64.08  ? 89  GLU C CG  1 
ATOM   3415 C  CD  . GLU C 1 89  ? 7.214   -38.721 -7.067  1.00 76.89  ? 89  GLU C CD  1 
ATOM   3416 O  OE1 . GLU C 1 89  ? 6.504   -37.712 -6.860  1.00 76.25  ? 89  GLU C OE1 1 
ATOM   3417 O  OE2 . GLU C 1 89  ? 7.804   -38.949 -8.151  1.00 79.44  ? 89  GLU C OE2 1 
ATOM   3418 N  N   . TRP C 1 90  ? 10.162  -39.634 -1.997  1.00 44.87  ? 90  TRP C N   1 
ATOM   3419 C  CA  . TRP C 1 90  ? 10.454  -39.291 -0.628  1.00 50.40  ? 90  TRP C CA  1 
ATOM   3420 C  C   . TRP C 1 90  ? 10.800  -37.830 -0.470  1.00 47.17  ? 90  TRP C C   1 
ATOM   3421 O  O   . TRP C 1 90  ? 11.179  -37.420 0.626   1.00 43.52  ? 90  TRP C O   1 
ATOM   3422 C  CB  . TRP C 1 90  ? 11.552  -40.205 -0.119  1.00 41.79  ? 90  TRP C CB  1 
ATOM   3423 C  CG  . TRP C 1 90  ? 11.080  -41.620 -0.248  1.00 44.85  ? 90  TRP C CG  1 
ATOM   3424 C  CD1 . TRP C 1 90  ? 11.291  -42.481 -1.303  1.00 41.74  ? 90  TRP C CD1 1 
ATOM   3425 C  CD2 . TRP C 1 90  ? 10.273  -42.327 0.691   1.00 42.05  ? 90  TRP C CD2 1 
ATOM   3426 N  NE1 . TRP C 1 90  ? 10.678  -43.687 -1.056  1.00 37.44  ? 90  TRP C NE1 1 
ATOM   3427 C  CE2 . TRP C 1 90  ? 10.058  -43.622 0.168   1.00 46.08  ? 90  TRP C CE2 1 
ATOM   3428 C  CE3 . TRP C 1 90  ? 9.730   -42.003 1.941   1.00 44.29  ? 90  TRP C CE3 1 
ATOM   3429 C  CZ2 . TRP C 1 90  ? 9.313   -44.586 0.854   1.00 45.66  ? 90  TRP C CZ2 1 
ATOM   3430 C  CZ3 . TRP C 1 90  ? 8.989   -42.961 2.620   1.00 40.94  ? 90  TRP C CZ3 1 
ATOM   3431 C  CH2 . TRP C 1 90  ? 8.789   -44.233 2.073   1.00 43.85  ? 90  TRP C CH2 1 
ATOM   3432 N  N   . GLY C 1 91  ? 10.625  -37.033 -1.525  1.00 46.45  ? 91  GLY C N   1 
ATOM   3433 C  CA  . GLY C 1 91  ? 10.882  -35.611 -1.418  1.00 36.59  ? 91  GLY C CA  1 
ATOM   3434 C  C   . GLY C 1 91  ? 12.365  -35.371 -1.303  1.00 41.91  ? 91  GLY C C   1 
ATOM   3435 O  O   . GLY C 1 91  ? 13.177  -36.032 -1.959  1.00 47.83  ? 91  GLY C O   1 
ATOM   3436 N  N   . THR C 1 92  ? 12.731  -34.435 -0.435  1.00 43.88  ? 92  THR C N   1 
ATOM   3437 C  CA  . THR C 1 92  ? 14.120  -34.032 -0.262  1.00 40.54  ? 92  THR C CA  1 
ATOM   3438 C  C   . THR C 1 92  ? 14.893  -35.045 0.562   1.00 41.85  ? 92  THR C C   1 
ATOM   3439 O  O   . THR C 1 92  ? 14.319  -35.891 1.252   1.00 45.94  ? 92  THR C O   1 
ATOM   3440 C  CB  . THR C 1 92  ? 14.187  -32.713 0.464   1.00 43.80  ? 92  THR C CB  1 
ATOM   3441 O  OG1 . THR C 1 92  ? 13.757  -32.963 1.806   1.00 43.12  ? 92  THR C OG1 1 
ATOM   3442 C  CG2 . THR C 1 92  ? 13.270  -31.656 -0.212  1.00 33.83  ? 92  THR C CG2 1 
ATOM   3443 N  N   . GLY C 1 93  ? 16.219  -34.928 0.513   1.00 42.08  ? 93  GLY C N   1 
ATOM   3444 C  CA  . GLY C 1 93  ? 17.045  -35.749 1.378   1.00 42.57  ? 93  GLY C CA  1 
ATOM   3445 C  C   . GLY C 1 93  ? 16.627  -35.638 2.833   1.00 44.75  ? 93  GLY C C   1 
ATOM   3446 O  O   . GLY C 1 93  ? 16.559  -36.641 3.555   1.00 40.79  ? 93  GLY C O   1 
ATOM   3447 N  N   . LEU C 1 94  ? 16.312  -34.419 3.277   1.00 39.34  ? 94  LEU C N   1 
ATOM   3448 C  CA  . LEU C 1 94  ? 15.904  -34.230 4.663   1.00 44.76  ? 94  LEU C CA  1 
ATOM   3449 C  C   . LEU C 1 94  ? 14.621  -34.997 4.962   1.00 41.64  ? 94  LEU C C   1 
ATOM   3450 O  O   . LEU C 1 94  ? 14.525  -35.693 5.980   1.00 44.43  ? 94  LEU C O   1 
ATOM   3451 C  CB  . LEU C 1 94  ? 15.739  -32.738 4.979   1.00 39.62  ? 94  LEU C CB  1 
ATOM   3452 C  CG  . LEU C 1 94  ? 15.193  -32.443 6.384   1.00 41.78  ? 94  LEU C CG  1 
ATOM   3453 C  CD1 . LEU C 1 94  ? 16.137  -32.985 7.456   1.00 43.54  ? 94  LEU C CD1 1 
ATOM   3454 C  CD2 . LEU C 1 94  ? 14.965  -30.973 6.580   1.00 36.94  ? 94  LEU C CD2 1 
ATOM   3455 N  N   . GLU C 1 95  ? 13.626  -34.902 4.075   1.00 44.54  ? 95  GLU C N   1 
ATOM   3456 C  CA  . GLU C 1 95  ? 12.363  -35.597 4.317   1.00 46.10  ? 95  GLU C CA  1 
ATOM   3457 C  C   . GLU C 1 95  ? 12.551  -37.111 4.305   1.00 38.58  ? 95  GLU C C   1 
ATOM   3458 O  O   . GLU C 1 95  ? 11.906  -37.830 5.075   1.00 37.90  ? 95  GLU C O   1 
ATOM   3459 C  CB  . GLU C 1 95  ? 11.319  -35.176 3.289   1.00 42.96  ? 95  GLU C CB  1 
ATOM   3460 C  CG  . GLU C 1 95  ? 10.732  -33.801 3.553   1.00 47.93  ? 95  GLU C CG  1 
ATOM   3461 C  CD  . GLU C 1 95  ? 10.117  -33.186 2.301   1.00 53.10  ? 95  GLU C CD  1 
ATOM   3462 O  OE1 . GLU C 1 95  ? 10.702  -33.347 1.195   1.00 49.30  ? 95  GLU C OE1 1 
ATOM   3463 O  OE2 . GLU C 1 95  ? 9.057   -32.540 2.428   1.00 55.15  ? 95  GLU C OE2 1 
ATOM   3464 N  N   . ALA C 1 96  ? 13.443  -37.614 3.457   1.00 32.00  ? 96  ALA C N   1 
ATOM   3465 C  CA  . ALA C 1 96  ? 13.738  -39.039 3.499   1.00 38.05  ? 96  ALA C CA  1 
ATOM   3466 C  C   . ALA C 1 96  ? 14.268  -39.442 4.874   1.00 45.01  ? 96  ALA C C   1 
ATOM   3467 O  O   . ALA C 1 96  ? 13.811  -40.431 5.467   1.00 38.45  ? 96  ALA C O   1 
ATOM   3468 C  CB  . ALA C 1 96  ? 14.733  -39.402 2.402   1.00 40.87  ? 96  ALA C CB  1 
ATOM   3469 N  N   . LEU C 1 97  ? 15.219  -38.668 5.410   1.00 40.14  ? 97  LEU C N   1 
ATOM   3470 C  CA  . LEU C 1 97  ? 15.811  -39.004 6.703   1.00 41.29  ? 97  LEU C CA  1 
ATOM   3471 C  C   . LEU C 1 97  ? 14.773  -38.953 7.823   1.00 41.44  ? 97  LEU C C   1 
ATOM   3472 O  O   . LEU C 1 97  ? 14.755  -39.819 8.701   1.00 37.34  ? 97  LEU C O   1 
ATOM   3473 C  CB  . LEU C 1 97  ? 16.974  -38.055 6.988   1.00 45.96  ? 97  LEU C CB  1 
ATOM   3474 C  CG  . LEU C 1 97  ? 18.192  -38.231 6.073   1.00 45.00  ? 97  LEU C CG  1 
ATOM   3475 C  CD1 . LEU C 1 97  ? 19.177  -37.082 6.229   1.00 39.23  ? 97  LEU C CD1 1 
ATOM   3476 C  CD2 . LEU C 1 97  ? 18.856  -39.554 6.387   1.00 37.32  ? 97  LEU C CD2 1 
ATOM   3477 N  N   . GLN C 1 98  ? 13.889  -37.953 7.802   1.00 42.18  ? 98  GLN C N   1 
ATOM   3478 C  CA  . GLN C 1 98  ? 12.861  -37.855 8.835   1.00 38.57  ? 98  GLN C CA  1 
ATOM   3479 C  C   . GLN C 1 98  ? 11.907  -39.039 8.779   1.00 41.74  ? 98  GLN C C   1 
ATOM   3480 O  O   . GLN C 1 98  ? 11.502  -39.572 9.819   1.00 41.80  ? 98  GLN C O   1 
ATOM   3481 C  CB  . GLN C 1 98  ? 12.103  -36.537 8.689   1.00 32.12  ? 98  GLN C CB  1 
ATOM   3482 C  CG  . GLN C 1 98  ? 13.001  -35.338 8.928   1.00 46.47  ? 98  GLN C CG  1 
ATOM   3483 C  CD  . GLN C 1 98  ? 12.358  -34.000 8.569   1.00 52.40  ? 98  GLN C CD  1 
ATOM   3484 O  OE1 . GLN C 1 98  ? 11.496  -33.913 7.687   1.00 45.51  ? 98  GLN C OE1 1 
ATOM   3485 N  NE2 . GLN C 1 98  ? 12.777  -32.944 9.270   1.00 56.50  ? 98  GLN C NE2 1 
ATOM   3486 N  N   . ALA C 1 99  ? 11.539  -39.466 7.568   1.00 43.35  ? 99  ALA C N   1 
ATOM   3487 C  CA  . ALA C 1 99  ? 10.757  -40.688 7.410   1.00 38.95  ? 99  ALA C CA  1 
ATOM   3488 C  C   . ALA C 1 99  ? 11.518  -41.906 7.932   1.00 43.95  ? 99  ALA C C   1 
ATOM   3489 O  O   . ALA C 1 99  ? 10.933  -42.788 8.574   1.00 42.77  ? 99  ALA C O   1 
ATOM   3490 C  CB  . ALA C 1 99  ? 10.392  -40.874 5.940   1.00 32.82  ? 99  ALA C CB  1 
ATOM   3491 N  N   . ALA C 1 100 ? 12.827  -41.965 7.674   1.00 41.94  ? 100 ALA C N   1 
ATOM   3492 C  CA  . ALA C 1 100 ? 13.619  -43.100 8.128   1.00 44.36  ? 100 ALA C CA  1 
ATOM   3493 C  C   . ALA C 1 100 ? 13.738  -43.116 9.648   1.00 48.90  ? 100 ALA C C   1 
ATOM   3494 O  O   . ALA C 1 100 ? 13.740  -44.191 10.267  1.00 47.02  ? 100 ALA C O   1 
ATOM   3495 C  CB  . ALA C 1 100 ? 14.997  -43.076 7.474   1.00 35.65  ? 100 ALA C CB  1 
ATOM   3496 N  N   . LEU C 1 101 ? 13.850  -41.942 10.270  1.00 43.61  ? 101 LEU C N   1 
ATOM   3497 C  CA  . LEU C 1 101 ? 13.867  -41.909 11.723  1.00 41.29  ? 101 LEU C CA  1 
ATOM   3498 C  C   . LEU C 1 101 ? 12.555  -42.446 12.276  1.00 50.53  ? 101 LEU C C   1 
ATOM   3499 O  O   . LEU C 1 101 ? 12.549  -43.270 13.197  1.00 48.90  ? 101 LEU C O   1 
ATOM   3500 C  CB  . LEU C 1 101 ? 14.140  -40.493 12.217  1.00 41.84  ? 101 LEU C CB  1 
ATOM   3501 C  CG  . LEU C 1 101 ? 14.211  -40.382 13.748  1.00 50.92  ? 101 LEU C CG  1 
ATOM   3502 C  CD1 . LEU C 1 101 ? 15.536  -40.879 14.279  1.00 48.45  ? 101 LEU C CD1 1 
ATOM   3503 C  CD2 . LEU C 1 101 ? 14.029  -38.953 14.149  1.00 50.31  ? 101 LEU C CD2 1 
ATOM   3504 N  N   . ASP C 1 102 ? 11.431  -42.012 11.691  1.00 49.93  ? 102 ASP C N   1 
ATOM   3505 C  CA  . ASP C 1 102 ? 10.124  -42.554 12.061  1.00 50.90  ? 102 ASP C CA  1 
ATOM   3506 C  C   . ASP C 1 102 ? 10.082  -44.060 11.890  1.00 51.51  ? 102 ASP C C   1 
ATOM   3507 O  O   . ASP C 1 102 ? 9.554   -44.776 12.751  1.00 53.57  ? 102 ASP C O   1 
ATOM   3508 C  CB  . ASP C 1 102 ? 9.021   -41.926 11.209  1.00 49.02  ? 102 ASP C CB  1 
ATOM   3509 C  CG  . ASP C 1 102 ? 8.763   -40.495 11.571  1.00 64.17  ? 102 ASP C CG  1 
ATOM   3510 O  OD1 . ASP C 1 102 ? 9.259   -40.072 12.644  1.00 65.19  ? 102 ASP C OD1 1 
ATOM   3511 O  OD2 . ASP C 1 102 ? 8.071   -39.795 10.790  1.00 72.26  ? 102 ASP C OD2 1 
ATOM   3512 N  N   . LEU C 1 103 ? 10.589  -44.545 10.755  1.00 48.90  ? 103 LEU C N   1 
ATOM   3513 C  CA  . LEU C 1 103 ? 10.623  -45.976 10.490  1.00 44.10  ? 103 LEU C CA  1 
ATOM   3514 C  C   . LEU C 1 103 ? 11.388  -46.695 11.581  1.00 48.41  ? 103 LEU C C   1 
ATOM   3515 O  O   . LEU C 1 103 ? 10.916  -47.690 12.138  1.00 55.50  ? 103 LEU C O   1 
ATOM   3516 C  CB  . LEU C 1 103 ? 11.266  -46.233 9.131   1.00 42.50  ? 103 LEU C CB  1 
ATOM   3517 C  CG  . LEU C 1 103 ? 11.340  -47.697 8.706   1.00 41.59  ? 103 LEU C CG  1 
ATOM   3518 C  CD1 . LEU C 1 103 ? 9.939   -48.235 8.572   1.00 41.97  ? 103 LEU C CD1 1 
ATOM   3519 C  CD2 . LEU C 1 103 ? 12.098  -47.838 7.399   1.00 33.93  ? 103 LEU C CD2 1 
ATOM   3520 N  N   . GLU C 1 104 ? 12.562  -46.175 11.926  1.00 48.19  ? 104 GLU C N   1 
ATOM   3521 C  CA  . GLU C 1 104 ? 13.406  -46.851 12.894  1.00 54.63  ? 104 GLU C CA  1 
ATOM   3522 C  C   . GLU C 1 104 ? 12.737  -46.885 14.260  1.00 58.86  ? 104 GLU C C   1 
ATOM   3523 O  O   . GLU C 1 104 ? 12.765  -47.913 14.943  1.00 59.99  ? 104 GLU C O   1 
ATOM   3524 C  CB  . GLU C 1 104 ? 14.772  -46.167 12.950  1.00 55.31  ? 104 GLU C CB  1 
ATOM   3525 C  CG  . GLU C 1 104 ? 15.681  -46.496 11.766  1.00 58.28  ? 104 GLU C CG  1 
ATOM   3526 C  CD  . GLU C 1 104 ? 16.243  -47.917 11.811  1.00 68.36  ? 104 GLU C CD  1 
ATOM   3527 O  OE1 . GLU C 1 104 ? 16.229  -48.595 10.759  1.00 60.48  ? 104 GLU C OE1 1 
ATOM   3528 O  OE2 . GLU C 1 104 ? 16.698  -48.354 12.899  1.00 80.28  ? 104 GLU C OE2 1 
ATOM   3529 N  N   . LYS C 1 105 ? 12.093  -45.781 14.654  1.00 58.46  ? 105 LYS C N   1 
ATOM   3530 C  CA  . LYS C 1 105 ? 11.350  -45.756 15.911  1.00 57.22  ? 105 LYS C CA  1 
ATOM   3531 C  C   . LYS C 1 105 ? 10.173  -46.721 15.873  1.00 55.26  ? 105 LYS C C   1 
ATOM   3532 O  O   . LYS C 1 105 ? 9.856   -47.361 16.878  1.00 61.10  ? 105 LYS C O   1 
ATOM   3533 C  CB  . LYS C 1 105 ? 10.852  -44.343 16.205  1.00 54.34  ? 105 LYS C CB  1 
ATOM   3534 C  CG  . LYS C 1 105 ? 11.922  -43.358 16.640  1.00 60.61  ? 105 LYS C CG  1 
ATOM   3535 C  CD  . LYS C 1 105 ? 11.314  -41.961 16.753  1.00 58.42  ? 105 LYS C CD  1 
ATOM   3536 C  CE  . LYS C 1 105 ? 12.321  -40.943 17.230  1.00 63.52  ? 105 LYS C CE  1 
ATOM   3537 N  NZ  . LYS C 1 105 ? 11.704  -39.596 17.233  1.00 65.36  ? 105 LYS C NZ  1 
ATOM   3538 N  N   . GLN C 1 106 ? 9.501   -46.820 14.729  1.00 52.45  ? 106 GLN C N   1 
ATOM   3539 C  CA  . GLN C 1 106 ? 8.395   -47.762 14.602  1.00 55.20  ? 106 GLN C CA  1 
ATOM   3540 C  C   . GLN C 1 106 ? 8.897   -49.205 14.707  1.00 66.14  ? 106 GLN C C   1 
ATOM   3541 O  O   . GLN C 1 106 ? 8.250   -50.052 15.337  1.00 67.56  ? 106 GLN C O   1 
ATOM   3542 C  CB  . GLN C 1 106 ? 7.652   -47.496 13.281  1.00 57.06  ? 106 GLN C CB  1 
ATOM   3543 C  CG  . GLN C 1 106 ? 6.707   -48.603 12.762  1.00 64.33  ? 106 GLN C CG  1 
ATOM   3544 C  CD  . GLN C 1 106 ? 6.240   -48.371 11.300  1.00 66.79  ? 106 GLN C CD  1 
ATOM   3545 O  OE1 . GLN C 1 106 ? 6.457   -47.304 10.717  1.00 66.38  ? 106 GLN C OE1 1 
ATOM   3546 N  NE2 . GLN C 1 106 ? 5.600   -49.381 10.716  1.00 62.93  ? 106 GLN C NE2 1 
ATOM   3547 N  N   . VAL C 1 107 ? 10.069  -49.496 14.134  1.00 62.04  ? 107 VAL C N   1 
ATOM   3548 C  CA  . VAL C 1 107 ? 10.613  -50.845 14.233  1.00 62.06  ? 107 VAL C CA  1 
ATOM   3549 C  C   . VAL C 1 107 ? 11.043  -51.145 15.664  1.00 62.14  ? 107 VAL C C   1 
ATOM   3550 O  O   . VAL C 1 107 ? 10.887  -52.276 16.143  1.00 59.87  ? 107 VAL C O   1 
ATOM   3551 C  CB  . VAL C 1 107 ? 11.775  -51.032 13.236  1.00 59.94  ? 107 VAL C CB  1 
ATOM   3552 C  CG1 . VAL C 1 107 ? 12.606  -52.278 13.579  1.00 56.76  ? 107 VAL C CG1 1 
ATOM   3553 C  CG2 . VAL C 1 107 ? 11.249  -51.118 11.817  1.00 43.38  ? 107 VAL C CG2 1 
ATOM   3554 N  N   . ASN C 1 108 ? 11.555  -50.145 16.379  1.00 60.76  ? 108 ASN C N   1 
ATOM   3555 C  CA  . ASN C 1 108 ? 12.075  -50.364 17.723  1.00 65.18  ? 108 ASN C CA  1 
ATOM   3556 C  C   . ASN C 1 108 ? 11.004  -50.296 18.807  1.00 65.14  ? 108 ASN C C   1 
ATOM   3557 O  O   . ASN C 1 108 ? 11.167  -50.922 19.862  1.00 66.84  ? 108 ASN C O   1 
ATOM   3558 C  CB  . ASN C 1 108 ? 13.205  -49.369 18.010  1.00 68.83  ? 108 ASN C CB  1 
ATOM   3559 C  CG  . ASN C 1 108 ? 14.344  -49.502 17.010  1.00 75.25  ? 108 ASN C CG  1 
ATOM   3560 O  OD1 . ASN C 1 108 ? 14.915  -48.510 16.548  1.00 78.08  ? 108 ASN C OD1 1 
ATOM   3561 N  ND2 . ASN C 1 108 ? 14.651  -50.744 16.635  1.00 78.10  ? 108 ASN C ND2 1 
ATOM   3562 N  N   . GLN C 1 109 ? 9.915   -49.561 18.581  1.00 63.56  ? 109 GLN C N   1 
ATOM   3563 C  CA  . GLN C 1 109 ? 8.749   -49.693 19.447  1.00 63.93  ? 109 GLN C CA  1 
ATOM   3564 C  C   . GLN C 1 109 ? 8.239   -51.127 19.437  1.00 63.90  ? 109 GLN C C   1 
ATOM   3565 O  O   . GLN C 1 109 ? 8.055   -51.747 20.489  1.00 59.17  ? 109 GLN C O   1 
ATOM   3566 C  CB  . GLN C 1 109 ? 7.647   -48.737 18.993  1.00 68.05  ? 109 GLN C CB  1 
ATOM   3567 C  CG  . GLN C 1 109 ? 6.452   -48.684 19.933  1.00 75.56  ? 109 GLN C CG  1 
ATOM   3568 C  CD  . GLN C 1 109 ? 6.805   -48.050 21.266  1.00 77.53  ? 109 GLN C CD  1 
ATOM   3569 O  OE1 . GLN C 1 109 ? 7.489   -47.024 21.320  1.00 77.18  ? 109 GLN C OE1 1 
ATOM   3570 N  NE2 . GLN C 1 109 ? 6.352   -48.667 22.349  1.00 77.90  ? 109 GLN C NE2 1 
ATOM   3571 N  N   . SER C 1 110 ? 8.009   -51.662 18.238  1.00 65.31  ? 110 SER C N   1 
ATOM   3572 C  CA  . SER C 1 110 ? 7.636   -53.060 18.057  1.00 58.96  ? 110 SER C CA  1 
ATOM   3573 C  C   . SER C 1 110 ? 8.625   -54.007 18.735  1.00 62.33  ? 110 SER C C   1 
ATOM   3574 O  O   . SER C 1 110 ? 8.228   -55.044 19.277  1.00 62.49  ? 110 SER C O   1 
ATOM   3575 C  CB  . SER C 1 110 ? 7.531   -53.339 16.558  1.00 55.91  ? 110 SER C CB  1 
ATOM   3576 O  OG  . SER C 1 110 ? 7.584   -54.714 16.247  1.00 57.27  ? 110 SER C OG  1 
ATOM   3577 N  N   . LEU C 1 111 ? 9.915   -53.665 18.727  1.00 58.61  ? 111 LEU C N   1 
ATOM   3578 C  CA  . LEU C 1 111 ? 10.891  -54.463 19.459  1.00 55.67  ? 111 LEU C CA  1 
ATOM   3579 C  C   . LEU C 1 111 ? 10.593  -54.452 20.957  1.00 67.98  ? 111 LEU C C   1 
ATOM   3580 O  O   . LEU C 1 111 ? 10.598  -55.506 21.606  1.00 72.12  ? 111 LEU C O   1 
ATOM   3581 C  CB  . LEU C 1 111 ? 12.305  -53.953 19.181  1.00 63.33  ? 111 LEU C CB  1 
ATOM   3582 C  CG  . LEU C 1 111 ? 13.171  -54.664 18.131  1.00 64.35  ? 111 LEU C CG  1 
ATOM   3583 C  CD1 . LEU C 1 111 ? 14.388  -53.816 17.830  1.00 71.68  ? 111 LEU C CD1 1 
ATOM   3584 C  CD2 . LEU C 1 111 ? 13.602  -56.064 18.560  1.00 57.98  ? 111 LEU C CD2 1 
ATOM   3585 N  N   . LEU C 1 112 ? 10.322  -53.267 21.524  1.00 68.55  ? 112 LEU C N   1 
ATOM   3586 C  CA  . LEU C 1 112 ? 9.965   -53.175 22.943  1.00 70.12  ? 112 LEU C CA  1 
ATOM   3587 C  C   . LEU C 1 112 ? 8.721   -53.997 23.280  1.00 64.75  ? 112 LEU C C   1 
ATOM   3588 O  O   . LEU C 1 112 ? 8.689   -54.702 24.294  1.00 64.34  ? 112 LEU C O   1 
ATOM   3589 C  CB  . LEU C 1 112 ? 9.743   -51.719 23.345  1.00 68.08  ? 112 LEU C CB  1 
ATOM   3590 C  CG  . LEU C 1 112 ? 10.953  -50.996 23.903  1.00 74.89  ? 112 LEU C CG  1 
ATOM   3591 C  CD1 . LEU C 1 112 ? 10.511  -49.659 24.458  1.00 82.49  ? 112 LEU C CD1 1 
ATOM   3592 C  CD2 . LEU C 1 112 ? 11.592  -51.849 24.978  1.00 76.85  ? 112 LEU C CD2 1 
ATOM   3593 N  N   . GLU C 1 113 ? 7.669   -53.881 22.466  1.00 52.97  ? 113 GLU C N   1 
ATOM   3594 C  CA  . GLU C 1 113 ? 6.467   -54.662 22.708  1.00 63.15  ? 113 GLU C CA  1 
ATOM   3595 C  C   . GLU C 1 113 ? 6.795   -56.146 22.786  1.00 68.57  ? 113 GLU C C   1 
ATOM   3596 O  O   . GLU C 1 113 ? 6.215   -56.882 23.593  1.00 72.93  ? 113 GLU C O   1 
ATOM   3597 C  CB  . GLU C 1 113 ? 5.426   -54.372 21.623  1.00 66.64  ? 113 GLU C CB  1 
ATOM   3598 C  CG  . GLU C 1 113 ? 4.799   -52.975 21.756  1.00 73.24  ? 113 GLU C CG  1 
ATOM   3599 C  CD  . GLU C 1 113 ? 4.096   -52.474 20.490  1.00 81.67  ? 113 GLU C CD  1 
ATOM   3600 O  OE1 . GLU C 1 113 ? 3.767   -53.295 19.597  1.00 79.05  ? 113 GLU C OE1 1 
ATOM   3601 O  OE2 . GLU C 1 113 ? 3.884   -51.239 20.395  1.00 83.62  ? 113 GLU C OE2 1 
ATOM   3602 N  N   . LEU C 1 114 ? 7.754   -56.598 21.983  1.00 65.09  ? 114 LEU C N   1 
ATOM   3603 C  CA  . LEU C 1 114 ? 8.143   -57.997 22.052  1.00 62.61  ? 114 LEU C CA  1 
ATOM   3604 C  C   . LEU C 1 114 ? 9.046   -58.261 23.252  1.00 68.72  ? 114 LEU C C   1 
ATOM   3605 O  O   . LEU C 1 114 ? 9.092   -59.388 23.761  1.00 67.82  ? 114 LEU C O   1 
ATOM   3606 C  CB  . LEU C 1 114 ? 8.792   -58.401 20.730  1.00 54.50  ? 114 LEU C CB  1 
ATOM   3607 C  CG  . LEU C 1 114 ? 9.669   -59.632 20.636  1.00 59.07  ? 114 LEU C CG  1 
ATOM   3608 C  CD1 . LEU C 1 114 ? 8.849   -60.885 20.820  1.00 62.88  ? 114 LEU C CD1 1 
ATOM   3609 C  CD2 . LEU C 1 114 ? 10.339  -59.651 19.285  1.00 57.16  ? 114 LEU C CD2 1 
ATOM   3610 N  N   . HIS C 1 115 ? 9.733   -57.228 23.747  1.00 66.36  ? 115 HIS C N   1 
ATOM   3611 C  CA  . HIS C 1 115 ? 10.537  -57.387 24.953  1.00 66.18  ? 115 HIS C CA  1 
ATOM   3612 C  C   . HIS C 1 115 ? 9.672   -57.556 26.201  1.00 67.99  ? 115 HIS C C   1 
ATOM   3613 O  O   . HIS C 1 115 ? 10.072  -58.255 27.140  1.00 70.21  ? 115 HIS C O   1 
ATOM   3614 C  CB  . HIS C 1 115 ? 11.470  -56.195 25.126  1.00 60.76  ? 115 HIS C CB  1 
ATOM   3615 C  CG  . HIS C 1 115 ? 12.391  -56.326 26.296  1.00 61.39  ? 115 HIS C CG  1 
ATOM   3616 N  ND1 . HIS C 1 115 ? 12.042  -55.925 27.566  1.00 59.40  ? 115 HIS C ND1 1 
ATOM   3617 C  CD2 . HIS C 1 115 ? 13.644  -56.833 26.390  1.00 63.65  ? 115 HIS C CD2 1 
ATOM   3618 C  CE1 . HIS C 1 115 ? 13.044  -56.170 28.390  1.00 62.60  ? 115 HIS C CE1 1 
ATOM   3619 N  NE2 . HIS C 1 115 ? 14.029  -56.720 27.703  1.00 59.23  ? 115 HIS C NE2 1 
ATOM   3620 N  N   . SER C 1 116 ? 8.500   -56.921 26.239  1.00 63.24  ? 116 SER C N   1 
ATOM   3621 C  CA  . SER C 1 116 ? 7.605   -57.097 27.376  1.00 67.60  ? 116 SER C CA  1 
ATOM   3622 C  C   . SER C 1 116 ? 6.916   -58.452 27.328  1.00 70.91  ? 116 SER C C   1 
ATOM   3623 O  O   . SER C 1 116 ? 6.754   -59.109 28.363  1.00 72.47  ? 116 SER C O   1 
ATOM   3624 C  CB  . SER C 1 116 ? 6.564   -55.978 27.411  1.00 58.68  ? 116 SER C CB  1 
ATOM   3625 O  OG  . SER C 1 116 ? 7.186   -54.708 27.388  1.00 71.19  ? 116 SER C OG  1 
ATOM   3626 N  N   . THR C 1 117 ? 6.495   -58.877 26.136  1.00 67.86  ? 117 THR C N   1 
ATOM   3627 C  CA  . THR C 1 117 ? 5.932   -60.212 25.987  1.00 71.50  ? 117 THR C CA  1 
ATOM   3628 C  C   . THR C 1 117 ? 6.948   -61.287 26.366  1.00 65.16  ? 117 THR C C   1 
ATOM   3629 O  O   . THR C 1 117 ? 6.588   -62.287 26.996  1.00 65.75  ? 117 THR C O   1 
ATOM   3630 C  CB  . THR C 1 117 ? 5.418   -60.383 24.553  1.00 72.65  ? 117 THR C CB  1 
ATOM   3631 O  OG1 . THR C 1 117 ? 4.338   -59.461 24.336  1.00 66.66  ? 117 THR C OG1 1 
ATOM   3632 C  CG2 . THR C 1 117 ? 4.932   -61.821 24.282  1.00 66.63  ? 117 THR C CG2 1 
ATOM   3633 N  N   . ALA C 1 118 ? 8.222   -61.082 26.040  1.00 63.99  ? 118 ALA C N   1 
ATOM   3634 C  CA  . ALA C 1 118 ? 9.244   -62.039 26.452  1.00 64.09  ? 118 ALA C CA  1 
ATOM   3635 C  C   . ALA C 1 118 ? 9.442   -62.026 27.963  1.00 66.53  ? 118 ALA C C   1 
ATOM   3636 O  O   . ALA C 1 118 ? 9.737   -63.063 28.567  1.00 67.51  ? 118 ALA C O   1 
ATOM   3637 C  CB  . ALA C 1 118 ? 10.559  -61.741 25.737  1.00 64.91  ? 118 ALA C CB  1 
ATOM   3638 N  N   . SER C 1 119 ? 9.294   -60.863 28.593  1.00 73.46  ? 119 SER C N   1 
ATOM   3639 C  CA  . SER C 1 119 ? 9.462   -60.778 30.042  1.00 74.47  ? 119 SER C CA  1 
ATOM   3640 C  C   . SER C 1 119 ? 8.249   -61.328 30.786  1.00 71.44  ? 119 SER C C   1 
ATOM   3641 O  O   . SER C 1 119 ? 8.403   -62.102 31.739  1.00 73.83  ? 119 SER C O   1 
ATOM   3642 C  CB  . SER C 1 119 ? 9.738   -59.328 30.457  1.00 69.88  ? 119 SER C CB  1 
ATOM   3643 O  OG  . SER C 1 119 ? 11.133  -59.076 30.523  1.00 75.32  ? 119 SER C OG  1 
ATOM   3644 N  N   . GLY C 1 120 ? 7.043   -60.951 30.361  1.00 68.13  ? 120 GLY C N   1 
ATOM   3645 C  CA  . GLY C 1 120 ? 5.819   -61.417 30.985  1.00 67.36  ? 120 GLY C CA  1 
ATOM   3646 C  C   . GLY C 1 120 ? 5.476   -62.858 30.658  1.00 76.17  ? 120 GLY C C   1 
ATOM   3647 O  O   . GLY C 1 120 ? 4.342   -63.300 30.873  1.00 78.48  ? 120 GLY C O   1 
ATOM   3648 N  N   . ASN C 1 121 ? 6.444   -63.592 30.102  1.00 74.07  ? 121 ASN C N   1 
ATOM   3649 C  CA  . ASN C 1 121 ? 6.336   -65.028 29.898  1.00 66.05  ? 121 ASN C CA  1 
ATOM   3650 C  C   . ASN C 1 121 ? 7.579   -65.747 30.394  1.00 69.46  ? 121 ASN C C   1 
ATOM   3651 O  O   . ASN C 1 121 ? 7.679   -66.967 30.235  1.00 71.85  ? 121 ASN C O   1 
ATOM   3652 C  CB  . ASN C 1 121 ? 6.098   -65.358 28.416  1.00 62.97  ? 121 ASN C CB  1 
ATOM   3653 C  CG  . ASN C 1 121 ? 4.629   -65.293 28.030  1.00 71.69  ? 121 ASN C CG  1 
ATOM   3654 O  OD1 . ASN C 1 121 ? 3.776   -65.893 28.687  1.00 76.05  ? 121 ASN C OD1 1 
ATOM   3655 N  ND2 . ASN C 1 121 ? 4.327   -64.563 26.958  1.00 65.19  ? 121 ASN C ND2 1 
ATOM   3656 N  N   . ASN C 1 122 ? 8.526   -65.021 30.982  1.00 70.15  ? 122 ASN C N   1 
ATOM   3657 C  CA  . ASN C 1 122 ? 9.710   -65.600 31.603  1.00 73.86  ? 122 ASN C CA  1 
ATOM   3658 C  C   . ASN C 1 122 ? 10.510  -66.417 30.589  1.00 76.29  ? 122 ASN C C   1 
ATOM   3659 O  O   . ASN C 1 122 ? 10.800  -67.605 30.770  1.00 76.54  ? 122 ASN C O   1 
ATOM   3660 C  CB  . ASN C 1 122 ? 9.318   -66.422 32.831  1.00 79.18  ? 122 ASN C CB  1 
ATOM   3661 C  CG  . ASN C 1 122 ? 8.700   -65.561 33.912  1.00 81.72  ? 122 ASN C CG  1 
ATOM   3662 O  OD1 . ASN C 1 122 ? 7.486   -65.350 33.935  1.00 79.69  ? 122 ASN C OD1 1 
ATOM   3663 N  ND2 . ASN C 1 122 ? 9.541   -65.026 34.796  1.00 87.98  ? 122 ASN C ND2 1 
ATOM   3664 N  N   . ASP C 1 123 ? 10.845  -65.743 29.500  1.00 70.42  ? 123 ASP C N   1 
ATOM   3665 C  CA  . ASP C 1 123 ? 11.764  -66.270 28.512  1.00 67.73  ? 123 ASP C CA  1 
ATOM   3666 C  C   . ASP C 1 123 ? 13.028  -65.438 28.642  1.00 62.45  ? 123 ASP C C   1 
ATOM   3667 O  O   . ASP C 1 123 ? 13.249  -64.503 27.861  1.00 65.58  ? 123 ASP C O   1 
ATOM   3668 C  CB  . ASP C 1 123 ? 11.169  -66.202 27.103  1.00 64.73  ? 123 ASP C CB  1 
ATOM   3669 C  CG  . ASP C 1 123 ? 11.877  -67.117 26.129  1.00 59.85  ? 123 ASP C CG  1 
ATOM   3670 O  OD1 . ASP C 1 123 ? 13.003  -67.567 26.436  1.00 59.55  ? 123 ASP C OD1 1 
ATOM   3671 O  OD2 . ASP C 1 123 ? 11.297  -67.392 25.059  1.00 69.19  ? 123 ASP C OD2 1 
ATOM   3672 N  N   . PRO C 1 124 ? 13.871  -65.742 29.627  1.00 65.55  ? 124 PRO C N   1 
ATOM   3673 C  CA  . PRO C 1 124 ? 15.046  -64.893 29.881  1.00 67.10  ? 124 PRO C CA  1 
ATOM   3674 C  C   . PRO C 1 124 ? 15.938  -64.733 28.683  1.00 72.59  ? 124 PRO C C   1 
ATOM   3675 O  O   . PRO C 1 124 ? 16.673  -63.735 28.592  1.00 74.81  ? 124 PRO C O   1 
ATOM   3676 C  CB  . PRO C 1 124 ? 15.782  -65.636 31.001  1.00 62.43  ? 124 PRO C CB  1 
ATOM   3677 C  CG  . PRO C 1 124 ? 15.313  -67.037 30.895  1.00 60.68  ? 124 PRO C CG  1 
ATOM   3678 C  CD  . PRO C 1 124 ? 13.875  -66.950 30.464  1.00 65.89  ? 124 PRO C CD  1 
ATOM   3679 N  N   . CYS C 1 125 ? 15.904  -65.684 27.756  1.00 68.97  ? 125 CYS C N   1 
ATOM   3680 C  CA  . CYS C 1 125 ? 16.912  -65.706 26.725  1.00 66.66  ? 125 CYS C CA  1 
ATOM   3681 C  C   . CYS C 1 125 ? 16.387  -65.179 25.397  1.00 64.47  ? 125 CYS C C   1 
ATOM   3682 O  O   . CYS C 1 125 ? 17.181  -64.912 24.491  1.00 62.07  ? 125 CYS C O   1 
ATOM   3683 C  CB  . CYS C 1 125 ? 17.483  -67.120 26.641  1.00 65.75  ? 125 CYS C CB  1 
ATOM   3684 S  SG  . CYS C 1 125 ? 18.883  -67.240 27.848  1.00 85.98  ? 125 CYS C SG  1 
ATOM   3685 N  N   . LEU C 1 126 ? 15.082  -64.930 25.298  1.00 58.74  ? 126 LEU C N   1 
ATOM   3686 C  CA  . LEU C 1 126 ? 14.595  -64.069 24.233  1.00 54.95  ? 126 LEU C CA  1 
ATOM   3687 C  C   . LEU C 1 126 ? 14.804  -62.596 24.599  1.00 65.55  ? 126 LEU C C   1 
ATOM   3688 O  O   . LEU C 1 126 ? 15.185  -61.785 23.745  1.00 60.68  ? 126 LEU C O   1 
ATOM   3689 C  CB  . LEU C 1 126 ? 13.127  -64.391 23.951  1.00 53.67  ? 126 LEU C CB  1 
ATOM   3690 C  CG  . LEU C 1 126 ? 12.308  -63.409 23.108  1.00 64.82  ? 126 LEU C CG  1 
ATOM   3691 C  CD1 . LEU C 1 126 ? 13.011  -63.132 21.784  1.00 59.50  ? 126 LEU C CD1 1 
ATOM   3692 C  CD2 . LEU C 1 126 ? 10.897  -63.965 22.872  1.00 55.69  ? 126 LEU C CD2 1 
ATOM   3693 N  N   . THR C 1 127 ? 14.588  -62.238 25.874  1.00 67.81  ? 127 THR C N   1 
ATOM   3694 C  CA  . THR C 1 127 ? 14.916  -60.889 26.327  1.00 62.13  ? 127 THR C CA  1 
ATOM   3695 C  C   . THR C 1 127 ? 16.404  -60.619 26.185  1.00 61.92  ? 127 THR C C   1 
ATOM   3696 O  O   . THR C 1 127 ? 16.807  -59.496 25.873  1.00 68.81  ? 127 THR C O   1 
ATOM   3697 C  CB  . THR C 1 127 ? 14.497  -60.668 27.784  1.00 65.94  ? 127 THR C CB  1 
ATOM   3698 O  OG1 . THR C 1 127 ? 15.433  -61.309 28.655  1.00 68.86  ? 127 THR C OG1 1 
ATOM   3699 C  CG2 . THR C 1 127 ? 13.110  -61.213 28.055  1.00 68.83  ? 127 THR C CG2 1 
ATOM   3700 N  N   . LYS C 1 128 ? 17.237  -61.633 26.418  1.00 56.12  ? 128 LYS C N   1 
ATOM   3701 C  CA  . LYS C 1 128 ? 18.666  -61.464 26.190  1.00 61.62  ? 128 LYS C CA  1 
ATOM   3702 C  C   . LYS C 1 128 ? 18.944  -61.085 24.741  1.00 71.23  ? 128 LYS C C   1 
ATOM   3703 O  O   . LYS C 1 128 ? 19.742  -60.183 24.465  1.00 79.85  ? 128 LYS C O   1 
ATOM   3704 C  CB  . LYS C 1 128 ? 19.417  -62.741 26.564  1.00 65.00  ? 128 LYS C CB  1 
ATOM   3705 C  CG  . LYS C 1 128 ? 20.900  -62.536 26.864  1.00 69.84  ? 128 LYS C CG  1 
ATOM   3706 C  CD  . LYS C 1 128 ? 21.779  -62.571 25.620  1.00 71.95  ? 128 LYS C CD  1 
ATOM   3707 C  CE  . LYS C 1 128 ? 23.159  -61.961 25.896  1.00 78.33  ? 128 LYS C CE  1 
ATOM   3708 N  NZ  . LYS C 1 128 ? 23.098  -60.589 26.489  1.00 70.03  ? 128 LYS C NZ  1 
ATOM   3709 N  N   . LEU C 1 129 ? 18.295  -61.769 23.798  1.00 68.57  ? 129 LEU C N   1 
ATOM   3710 C  CA  . LEU C 1 129 ? 18.547  -61.496 22.386  1.00 69.55  ? 129 LEU C CA  1 
ATOM   3711 C  C   . LEU C 1 129 ? 18.041  -60.115 21.990  1.00 72.56  ? 129 LEU C C   1 
ATOM   3712 O  O   . LEU C 1 129 ? 18.713  -59.398 21.237  1.00 72.79  ? 129 LEU C O   1 
ATOM   3713 C  CB  . LEU C 1 129 ? 17.900  -62.574 21.510  1.00 66.11  ? 129 LEU C CB  1 
ATOM   3714 C  CG  . LEU C 1 129 ? 17.627  -62.148 20.060  1.00 64.82  ? 129 LEU C CG  1 
ATOM   3715 C  CD1 . LEU C 1 129 ? 18.932  -62.038 19.271  1.00 63.55  ? 129 LEU C CD1 1 
ATOM   3716 C  CD2 . LEU C 1 129 ? 16.631  -63.070 19.369  1.00 54.87  ? 129 LEU C CD2 1 
ATOM   3717 N  N   . LEU C 1 130 ? 16.862  -59.723 22.484  1.00 68.86  ? 130 LEU C N   1 
ATOM   3718 C  CA  . LEU C 1 130 ? 16.300  -58.430 22.106  1.00 71.11  ? 130 LEU C CA  1 
ATOM   3719 C  C   . LEU C 1 130 ? 17.114  -57.272 22.660  1.00 79.65  ? 130 LEU C C   1 
ATOM   3720 O  O   . LEU C 1 130 ? 17.142  -56.194 22.057  1.00 83.13  ? 130 LEU C O   1 
ATOM   3721 C  CB  . LEU C 1 130 ? 14.857  -58.322 22.575  1.00 66.13  ? 130 LEU C CB  1 
ATOM   3722 C  CG  . LEU C 1 130 ? 13.921  -59.456 22.182  1.00 67.45  ? 130 LEU C CG  1 
ATOM   3723 C  CD1 . LEU C 1 130 ? 12.527  -58.951 22.310  1.00 66.61  ? 130 LEU C CD1 1 
ATOM   3724 C  CD2 . LEU C 1 130 ? 14.191  -59.887 20.753  1.00 70.84  ? 130 LEU C CD2 1 
ATOM   3725 N  N   . GLU C 1 131 ? 17.774  -57.462 23.801  1.00 76.66  ? 131 GLU C N   1 
ATOM   3726 C  CA  . GLU C 1 131 ? 18.671  -56.422 24.279  1.00 80.49  ? 131 GLU C CA  1 
ATOM   3727 C  C   . GLU C 1 131 ? 19.853  -56.256 23.338  1.00 87.35  ? 131 GLU C C   1 
ATOM   3728 O  O   . GLU C 1 131 ? 20.372  -55.143 23.186  1.00 95.75  ? 131 GLU C O   1 
ATOM   3729 C  CB  . GLU C 1 131 ? 19.124  -56.733 25.707  1.00 87.09  ? 131 GLU C CB  1 
ATOM   3730 C  CG  . GLU C 1 131 ? 18.058  -56.349 26.748  1.00 82.76  ? 131 GLU C CG  1 
ATOM   3731 C  CD  . GLU C 1 131 ? 18.021  -57.255 27.970  1.00 75.05  ? 131 GLU C CD  1 
ATOM   3732 O  OE1 . GLU C 1 131 ? 19.087  -57.756 28.409  1.00 80.03  ? 131 GLU C OE1 1 
ATOM   3733 O  OE2 . GLU C 1 131 ? 16.906  -57.460 28.486  1.00 65.34  ? 131 GLU C OE2 1 
ATOM   3734 N  N   . ASP C 1 132 ? 20.255  -57.329 22.659  1.00 84.36  ? 132 ASP C N   1 
ATOM   3735 C  CA  . ASP C 1 132 ? 21.327  -57.253 21.669  1.00 95.54  ? 132 ASP C CA  1 
ATOM   3736 C  C   . ASP C 1 132 ? 20.853  -56.804 20.282  1.00 92.88  ? 132 ASP C C   1 
ATOM   3737 O  O   . ASP C 1 132 ? 21.659  -56.767 19.341  1.00 83.98  ? 132 ASP C O   1 
ATOM   3738 C  CB  . ASP C 1 132 ? 22.062  -58.596 21.600  1.00 86.66  ? 132 ASP C CB  1 
ATOM   3739 C  CG  . ASP C 1 132 ? 22.553  -59.056 22.970  1.00 86.28  ? 132 ASP C CG  1 
ATOM   3740 O  OD1 . ASP C 1 132 ? 23.237  -60.099 23.048  1.00 78.86  ? 132 ASP C OD1 1 
ATOM   3741 O  OD2 . ASP C 1 132 ? 22.247  -58.370 23.974  1.00 86.47  ? 132 ASP C OD2 1 
ATOM   3742 N  N   . GLU C 1 133 ? 19.578  -56.444 20.137  1.00 89.43  ? 133 GLU C N   1 
ATOM   3743 C  CA  . GLU C 1 133 ? 19.096  -55.724 18.964  1.00 90.66  ? 133 GLU C CA  1 
ATOM   3744 C  C   . GLU C 1 133 ? 18.627  -54.336 19.384  1.00 88.04  ? 133 GLU C C   1 
ATOM   3745 O  O   . GLU C 1 133 ? 19.280  -53.347 19.050  1.00 91.60  ? 133 GLU C O   1 
ATOM   3746 C  CB  . GLU C 1 133 ? 17.979  -56.495 18.245  1.00 85.47  ? 133 GLU C CB  1 
ATOM   3747 C  CG  . GLU C 1 133 ? 18.235  -58.000 18.068  1.00 79.54  ? 133 GLU C CG  1 
ATOM   3748 C  CD  . GLU C 1 133 ? 19.161  -58.327 16.908  1.00 78.55  ? 133 GLU C CD  1 
ATOM   3749 O  OE1 . GLU C 1 133 ? 18.686  -58.320 15.740  1.00 80.96  ? 133 GLU C OE1 1 
ATOM   3750 O  OE2 . GLU C 1 133 ? 20.360  -58.589 17.172  1.00 71.54  ? 133 GLU C OE2 1 
ATOM   3751 N  N   . TYR C 1 134 ? 17.539  -54.243 20.163  1.00 88.63  ? 134 TYR C N   1 
ATOM   3752 C  CA  . TYR C 1 134 ? 16.882  -52.967 20.469  1.00 92.02  ? 134 TYR C CA  1 
ATOM   3753 C  C   . TYR C 1 134 ? 17.788  -51.984 21.206  1.00 94.54  ? 134 TYR C C   1 
ATOM   3754 O  O   . TYR C 1 134 ? 17.528  -50.768 21.197  1.00 86.11  ? 134 TYR C O   1 
ATOM   3755 C  CB  . TYR C 1 134 ? 15.625  -53.209 21.315  1.00 87.15  ? 134 TYR C CB  1 
ATOM   3756 C  CG  . TYR C 1 134 ? 14.996  -51.929 21.834  1.00 89.98  ? 134 TYR C CG  1 
ATOM   3757 C  CD1 . TYR C 1 134 ? 15.026  -51.618 23.187  1.00 89.59  ? 134 TYR C CD1 1 
ATOM   3758 C  CD2 . TYR C 1 134 ? 14.385  -51.025 20.964  1.00 88.18  ? 134 TYR C CD2 1 
ATOM   3759 C  CE1 . TYR C 1 134 ? 14.469  -50.446 23.663  1.00 88.65  ? 134 TYR C CE1 1 
ATOM   3760 C  CE2 . TYR C 1 134 ? 13.822  -49.853 21.431  1.00 88.40  ? 134 TYR C CE2 1 
ATOM   3761 C  CZ  . TYR C 1 134 ? 13.865  -49.568 22.787  1.00 92.45  ? 134 TYR C CZ  1 
ATOM   3762 O  OH  . TYR C 1 134 ? 13.307  -48.402 23.277  1.00 92.63  ? 134 TYR C OH  1 
ATOM   3763 N  N   . CYS C 1 135 ? 18.824  -52.483 21.867  1.00 96.06  ? 135 CYS C N   1 
ATOM   3764 C  CA  . CYS C 1 135 ? 19.782  -51.627 22.559  1.00 91.71  ? 135 CYS C CA  1 
ATOM   3765 C  C   . CYS C 1 135 ? 21.102  -51.645 21.900  1.00 91.89  ? 135 CYS C C   1 
ATOM   3766 O  O   . CYS C 1 135 ? 21.575  -50.611 21.393  1.00 91.98  ? 135 CYS C O   1 
ATOM   3767 C  CB  . CYS C 1 135 ? 19.902  -52.071 24.025  1.00 88.57  ? 135 CYS C CB  1 
ATOM   3768 S  SG  . CYS C 1 135 ? 18.356  -52.462 24.830  1.00 87.34  ? 135 CYS C SG  1 
ATOM   3769 N  N   . GLU C 1 136 ? 21.746  -52.811 21.968  1.00 101.88 ? 136 GLU C N   1 
ATOM   3770 C  CA  . GLU C 1 136 ? 23.129  -53.075 21.482  1.00 110.44 ? 136 GLU C CA  1 
ATOM   3771 C  C   . GLU C 1 136 ? 23.599  -52.177 20.382  1.00 109.80 ? 136 GLU C C   1 
ATOM   3772 O  O   . GLU C 1 136 ? 24.618  -51.500 20.494  1.00 111.67 ? 136 GLU C O   1 
ATOM   3773 C  CB  . GLU C 1 136 ? 23.350  -54.536 21.111  1.00 103.65 ? 136 GLU C CB  1 
ATOM   3774 C  CG  . GLU C 1 136 ? 23.817  -55.375 22.283  1.00 104.08 ? 136 GLU C CG  1 
ATOM   3775 C  CD  . GLU C 1 136 ? 25.075  -54.839 22.922  1.00 111.07 ? 136 GLU C CD  1 
ATOM   3776 O  OE1 . GLU C 1 136 ? 26.138  -55.466 22.746  1.00 108.32 ? 136 GLU C OE1 1 
ATOM   3777 O  OE2 . GLU C 1 136 ? 25.002  -53.794 23.594  1.00 115.53 ? 136 GLU C OE2 1 
ATOM   3778 N  N   . GLU C 1 137 ? 22.762  -52.102 19.370  1.00 100.70 ? 137 GLU C N   1 
ATOM   3779 C  CA  . GLU C 1 137 ? 23.018  -51.187 18.313  1.00 101.54 ? 137 GLU C CA  1 
ATOM   3780 C  C   . GLU C 1 137 ? 21.828  -50.304 17.937  1.00 96.14  ? 137 GLU C C   1 
ATOM   3781 O  O   . GLU C 1 137 ? 21.962  -49.506 17.050  1.00 97.71  ? 137 GLU C O   1 
ATOM   3782 C  CB  . GLU C 1 137 ? 23.644  -51.893 17.108  1.00 104.22 ? 137 GLU C CB  1 
ATOM   3783 C  CG  . GLU C 1 137 ? 22.900  -53.125 16.620  1.00 109.48 ? 137 GLU C CG  1 
ATOM   3784 C  CD  . GLU C 1 137 ? 21.707  -52.796 15.761  1.00 103.13 ? 137 GLU C CD  1 
ATOM   3785 O  OE1 . GLU C 1 137 ? 20.711  -53.519 15.829  1.00 98.36  ? 137 GLU C OE1 1 
ATOM   3786 O  OE2 . GLU C 1 137 ? 21.762  -51.812 15.024  1.00 97.96  ? 137 GLU C OE2 1 
ATOM   3787 N  N   . GLN C 1 138 ? 20.654  -50.461 18.530  1.00 89.28  ? 138 GLN C N   1 
ATOM   3788 C  CA  . GLN C 1 138 ? 19.561  -49.578 18.104  1.00 88.60  ? 138 GLN C CA  1 
ATOM   3789 C  C   . GLN C 1 138 ? 19.753  -48.117 18.452  1.00 79.42  ? 138 GLN C C   1 
ATOM   3790 O  O   . GLN C 1 138 ? 19.456  -47.259 17.678  1.00 71.76  ? 138 GLN C O   1 
ATOM   3791 C  CB  . GLN C 1 138 ? 18.186  -50.085 18.481  1.00 86.26  ? 138 GLN C CB  1 
ATOM   3792 C  CG  . GLN C 1 138 ? 17.551  -51.007 17.454  1.00 88.70  ? 138 GLN C CG  1 
ATOM   3793 C  CD  . GLN C 1 138 ? 18.196  -51.012 16.078  1.00 91.06  ? 138 GLN C CD  1 
ATOM   3794 O  OE1 . GLN C 1 138 ? 18.352  -49.992 15.447  1.00 90.74  ? 138 GLN C OE1 1 
ATOM   3795 N  NE2 . GLN C 1 138 ? 18.523  -52.193 15.593  1.00 88.00  ? 138 GLN C NE2 1 
ATOM   3796 N  N   . CYS C 1 139 ? 20.252  -47.866 19.641  1.00 79.92  ? 139 CYS C N   1 
ATOM   3797 C  CA  . CYS C 1 139 ? 20.536  -46.545 20.135  1.00 75.32  ? 139 CYS C CA  1 
ATOM   3798 C  C   . CYS C 1 139 ? 21.615  -45.914 19.290  1.00 82.71  ? 139 CYS C C   1 
ATOM   3799 O  O   . CYS C 1 139 ? 21.585  -44.739 19.118  1.00 85.30  ? 139 CYS C O   1 
ATOM   3800 C  CB  . CYS C 1 139 ? 20.988  -46.641 21.592  1.00 84.90  ? 139 CYS C CB  1 
ATOM   3801 S  SG  . CYS C 1 139 ? 20.867  -45.210 22.694  1.00 102.49 ? 139 CYS C SG  1 
ATOM   3802 N  N   . ASP C 1 140 ? 22.628  -46.659 18.864  1.00 78.40  ? 140 ASP C N   1 
ATOM   3803 C  CA  . ASP C 1 140 ? 23.666  -46.117 17.993  1.00 75.94  ? 140 ASP C CA  1 
ATOM   3804 C  C   . ASP C 1 140 ? 23.066  -45.743 16.633  1.00 81.08  ? 140 ASP C C   1 
ATOM   3805 O  O   . ASP C 1 140 ? 23.404  -44.727 16.061  1.00 74.24  ? 140 ASP C O   1 
ATOM   3806 C  CB  . ASP C 1 140 ? 24.910  -47.010 17.924  1.00 75.47  ? 140 ASP C CB  1 
ATOM   3807 C  CG  . ASP C 1 140 ? 25.225  -47.537 16.518  1.00 96.04  ? 140 ASP C CG  1 
ATOM   3808 O  OD1 . ASP C 1 140 ? 26.388  -47.422 16.071  1.00 103.38 ? 140 ASP C OD1 1 
ATOM   3809 O  OD2 . ASP C 1 140 ? 24.335  -48.069 15.846  1.00 100.67 ? 140 ASP C OD2 1 
ATOM   3810 N  N   . SER C 1 141 ? 22.162  -46.569 16.111  1.00 76.72  ? 141 SER C N   1 
ATOM   3811 C  CA  A SER C 1 141 ? 21.493  -46.281 14.834  0.71 69.40  ? 141 SER C CA  1 
ATOM   3812 C  CA  B SER C 1 141 ? 21.432  -46.319 14.847  0.29 69.45  ? 141 SER C CA  1 
ATOM   3813 C  C   . SER C 1 141 ? 20.392  -45.131 14.671  1.00 68.41  ? 141 SER C C   1 
ATOM   3814 O  O   . SER C 1 141 ? 20.051  -44.373 13.688  1.00 59.89  ? 141 SER C O   1 
ATOM   3815 C  CB  A SER C 1 141 ? 20.972  -47.592 14.257  0.71 74.52  ? 141 SER C CB  1 
ATOM   3816 C  CB  B SER C 1 141 ? 20.779  -47.600 14.339  0.29 74.64  ? 141 SER C CB  1 
ATOM   3817 O  OG  A SER C 1 141 ? 20.272  -47.416 13.055  0.71 71.47  ? 141 SER C OG  1 
ATOM   3818 O  OG  B SER C 1 141 ? 21.731  -48.446 13.739  0.29 78.88  ? 141 SER C OG  1 
ATOM   3819 N  N   . ILE C 1 142 ? 19.711  -44.968 15.793  1.00 70.52  ? 142 ILE C N   1 
ATOM   3820 C  CA  . ILE C 1 142 ? 18.697  -43.952 15.949  1.00 64.41  ? 142 ILE C CA  1 
ATOM   3821 C  C   . ILE C 1 142 ? 19.441  -42.665 16.171  1.00 58.07  ? 142 ILE C C   1 
ATOM   3822 O  O   . ILE C 1 142 ? 19.072  -41.656 15.687  1.00 51.11  ? 142 ILE C O   1 
ATOM   3823 C  CB  . ILE C 1 142 ? 17.783  -44.241 17.135  1.00 63.06  ? 142 ILE C CB  1 
ATOM   3824 C  CG1 . ILE C 1 142 ? 16.773  -45.266 16.741  1.00 69.51  ? 142 ILE C CG1 1 
ATOM   3825 C  CG2 . ILE C 1 142 ? 16.954  -43.041 17.481  1.00 58.57  ? 142 ILE C CG2 1 
ATOM   3826 C  CD1 . ILE C 1 142 ? 15.711  -44.690 15.851  1.00 67.30  ? 142 ILE C CD1 1 
ATOM   3827 N  N   . LYS C 1 143 ? 20.491  -42.706 16.944  1.00 61.71  ? 143 LYS C N   1 
ATOM   3828 C  CA  . LYS C 1 143 ? 21.288  -41.499 17.107  1.00 58.05  ? 143 LYS C CA  1 
ATOM   3829 C  C   . LYS C 1 143 ? 21.929  -41.100 15.790  1.00 58.10  ? 143 LYS C C   1 
ATOM   3830 O  O   . LYS C 1 143 ? 22.038  -39.906 15.482  1.00 58.91  ? 143 LYS C O   1 
ATOM   3831 C  CB  . LYS C 1 143 ? 22.352  -41.704 18.185  1.00 60.46  ? 143 LYS C CB  1 
ATOM   3832 C  CG  . LYS C 1 143 ? 23.314  -40.540 18.360  1.00 66.31  ? 143 LYS C CG  1 
ATOM   3833 C  CD  . LYS C 1 143 ? 23.427  -40.166 19.831  1.00 70.60  ? 143 LYS C CD  1 
ATOM   3834 C  CE  . LYS C 1 143 ? 24.171  -38.851 20.005  1.00 65.50  ? 143 LYS C CE  1 
ATOM   3835 N  NZ  . LYS C 1 143 ? 25.276  -38.743 19.014  1.00 73.55  ? 143 LYS C NZ  1 
ATOM   3836 N  N   . LYS C 1 144 ? 22.335  -42.087 14.983  1.00 52.61  ? 144 LYS C N   1 
ATOM   3837 C  CA  . LYS C 1 144 ? 23.043  -41.760 13.754  1.00 47.96  ? 144 LYS C CA  1 
ATOM   3838 C  C   . LYS C 1 144 ? 22.131  -41.023 12.781  1.00 52.63  ? 144 LYS C C   1 
ATOM   3839 O  O   . LYS C 1 144 ? 22.536  -40.019 12.171  1.00 43.70  ? 144 LYS C O   1 
ATOM   3840 C  CB  . LYS C 1 144 ? 23.619  -43.029 13.124  1.00 59.17  ? 144 LYS C CB  1 
ATOM   3841 C  CG  . LYS C 1 144 ? 24.351  -42.772 11.826  1.00 63.27  ? 144 LYS C CG  1 
ATOM   3842 C  CD  . LYS C 1 144 ? 24.788  -44.030 11.087  1.00 58.82  ? 144 LYS C CD  1 
ATOM   3843 C  CE  . LYS C 1 144 ? 25.357  -43.622 9.719   1.00 64.06  ? 144 LYS C CE  1 
ATOM   3844 N  NZ  . LYS C 1 144 ? 26.792  -43.978 9.501   1.00 68.25  ? 144 LYS C NZ  1 
ATOM   3845 N  N   . ILE C 1 145 ? 20.884  -41.483 12.642  1.00 47.03  ? 145 ILE C N   1 
ATOM   3846 C  CA  . ILE C 1 145 ? 19.950  -40.765 11.782  1.00 50.70  ? 145 ILE C CA  1 
ATOM   3847 C  C   . ILE C 1 145 ? 19.594  -39.416 12.403  1.00 48.34  ? 145 ILE C C   1 
ATOM   3848 O  O   . ILE C 1 145 ? 19.491  -38.404 11.699  1.00 41.53  ? 145 ILE C O   1 
ATOM   3849 C  CB  . ILE C 1 145 ? 18.708  -41.632 11.493  1.00 46.98  ? 145 ILE C CB  1 
ATOM   3850 C  CG1 . ILE C 1 145 ? 19.104  -42.841 10.642  1.00 45.82  ? 145 ILE C CG1 1 
ATOM   3851 C  CG2 . ILE C 1 145 ? 17.658  -40.838 10.739  1.00 38.23  ? 145 ILE C CG2 1 
ATOM   3852 C  CD1 . ILE C 1 145 ? 17.943  -43.783 10.341  1.00 47.22  ? 145 ILE C CD1 1 
ATOM   3853 N  N   . GLY C 1 146 ? 19.426  -39.369 13.728  1.00 50.84  ? 146 GLY C N   1 
ATOM   3854 C  CA  . GLY C 1 146 ? 19.207  -38.087 14.384  1.00 45.60  ? 146 GLY C CA  1 
ATOM   3855 C  C   . GLY C 1 146 ? 20.321  -37.096 14.094  1.00 43.82  ? 146 GLY C C   1 
ATOM   3856 O  O   . GLY C 1 146 ? 20.073  -35.954 13.703  1.00 44.43  ? 146 GLY C O   1 
ATOM   3857 N  N   . CYS C 1 147 ? 21.568  -37.537 14.244  1.00 45.57  ? 147 CYS C N   1 
ATOM   3858 C  CA  . CYS C 1 147 ? 22.700  -36.669 13.934  1.00 43.86  ? 147 CYS C CA  1 
ATOM   3859 C  C   . CYS C 1 147 ? 22.733  -36.259 12.469  1.00 42.50  ? 147 CYS C C   1 
ATOM   3860 O  O   . CYS C 1 147 ? 23.011  -35.095 12.158  1.00 42.06  ? 147 CYS C O   1 
ATOM   3861 C  CB  . CYS C 1 147 ? 24.008  -37.340 14.328  1.00 43.60  ? 147 CYS C CB  1 
ATOM   3862 S  SG  . CYS C 1 147 ? 24.570  -36.739 15.942  1.00 60.72  ? 147 CYS C SG  1 
ATOM   3863 N  N   . MET C 1 148 ? 22.444  -37.186 11.551  1.00 42.18  ? 148 MET C N   1 
ATOM   3864 C  CA  . MET C 1 148 ? 22.409  -36.800 10.142  1.00 38.96  ? 148 MET C CA  1 
ATOM   3865 C  C   . MET C 1 148 ? 21.390  -35.699 9.903   1.00 40.95  ? 148 MET C C   1 
ATOM   3866 O  O   . MET C 1 148 ? 21.642  -34.757 9.136   1.00 40.30  ? 148 MET C O   1 
ATOM   3867 C  CB  . MET C 1 148 ? 22.102  -38.006 9.262   1.00 42.95  ? 148 MET C CB  1 
ATOM   3868 C  CG  . MET C 1 148 ? 23.164  -39.065 9.310   1.00 39.62  ? 148 MET C CG  1 
ATOM   3869 S  SD  . MET C 1 148 ? 22.605  -40.553 8.484   1.00 43.15  ? 148 MET C SD  1 
ATOM   3870 C  CE  . MET C 1 148 ? 22.506  -39.974 6.801   1.00 37.62  ? 148 MET C CE  1 
ATOM   3871 N  N   . ILE C 1 149 ? 20.232  -35.800 10.555  1.00 39.70  ? 149 ILE C N   1 
ATOM   3872 C  CA  . ILE C 1 149 ? 19.202  -34.784 10.383  1.00 40.83  ? 149 ILE C CA  1 
ATOM   3873 C  C   . ILE C 1 149 ? 19.696  -33.452 10.912  1.00 41.23  ? 149 ILE C C   1 
ATOM   3874 O  O   . ILE C 1 149 ? 19.560  -32.416 10.251  1.00 43.88  ? 149 ILE C O   1 
ATOM   3875 C  CB  . ILE C 1 149 ? 17.902  -35.216 11.078  1.00 44.11  ? 149 ILE C CB  1 
ATOM   3876 C  CG1 . ILE C 1 149 ? 17.225  -36.319 10.255  1.00 40.08  ? 149 ILE C CG1 1 
ATOM   3877 C  CG2 . ILE C 1 149 ? 17.002  -33.991 11.326  1.00 35.11  ? 149 ILE C CG2 1 
ATOM   3878 C  CD1 . ILE C 1 149 ? 16.019  -36.939 10.941  1.00 35.80  ? 149 ILE C CD1 1 
ATOM   3879 N  N   . THR C 1 150 ? 20.273  -33.462 12.121  1.00 43.15  ? 150 THR C N   1 
ATOM   3880 C  CA  . THR C 1 150 ? 20.856  -32.251 12.695  1.00 40.50  ? 150 THR C CA  1 
ATOM   3881 C  C   . THR C 1 150 ? 21.895  -31.660 11.759  1.00 39.75  ? 150 THR C C   1 
ATOM   3882 O  O   . THR C 1 150 ? 21.912  -30.447 11.498  1.00 43.41  ? 150 THR C O   1 
ATOM   3883 C  CB  . THR C 1 150 ? 21.485  -32.572 14.051  1.00 44.32  ? 150 THR C CB  1 
ATOM   3884 O  OG1 . THR C 1 150 ? 20.466  -33.034 14.948  1.00 42.73  ? 150 THR C OG1 1 
ATOM   3885 C  CG2 . THR C 1 150 ? 22.244  -31.332 14.652  1.00 31.60  ? 150 THR C CG2 1 
ATOM   3886 N  N   . LYS C 1 151 ? 22.758  -32.515 11.227  1.00 38.60  ? 151 LYS C N   1 
ATOM   3887 C  CA  . LYS C 1 151 ? 23.817  -32.045 10.347  1.00 40.14  ? 151 LYS C CA  1 
ATOM   3888 C  C   . LYS C 1 151 ? 23.250  -31.464 9.048   1.00 42.03  ? 151 LYS C C   1 
ATOM   3889 O  O   . LYS C 1 151 ? 23.690  -30.404 8.593   1.00 48.04  ? 151 LYS C O   1 
ATOM   3890 C  CB  . LYS C 1 151 ? 24.794  -33.190 10.088  1.00 34.37  ? 151 LYS C CB  1 
ATOM   3891 C  CG  . LYS C 1 151 ? 26.094  -32.744 9.460   1.00 52.76  ? 151 LYS C CG  1 
ATOM   3892 C  CD  . LYS C 1 151 ? 26.854  -33.902 8.835   1.00 41.14  ? 151 LYS C CD  1 
ATOM   3893 C  CE  . LYS C 1 151 ? 27.710  -33.409 7.688   1.00 45.17  ? 151 LYS C CE  1 
ATOM   3894 N  NZ  . LYS C 1 151 ? 28.866  -34.326 7.433   1.00 49.15  ? 151 LYS C NZ  1 
ATOM   3895 N  N   . LEU C 1 152 ? 22.251  -32.113 8.454   1.00 40.00  ? 152 LEU C N   1 
ATOM   3896 C  CA  . LEU C 1 152 ? 21.706  -31.603 7.200   1.00 43.83  ? 152 LEU C CA  1 
ATOM   3897 C  C   . LEU C 1 152 ? 20.986  -30.270 7.401   1.00 43.53  ? 152 LEU C C   1 
ATOM   3898 O  O   . LEU C 1 152 ? 21.096  -29.369 6.562   1.00 40.63  ? 152 LEU C O   1 
ATOM   3899 C  CB  . LEU C 1 152 ? 20.776  -32.645 6.576   1.00 46.45  ? 152 LEU C CB  1 
ATOM   3900 C  CG  . LEU C 1 152 ? 20.194  -32.312 5.200   1.00 43.20  ? 152 LEU C CG  1 
ATOM   3901 C  CD1 . LEU C 1 152 ? 21.302  -31.928 4.242   1.00 49.94  ? 152 LEU C CD1 1 
ATOM   3902 C  CD2 . LEU C 1 152 ? 19.424  -33.504 4.650   1.00 47.44  ? 152 LEU C CD2 1 
ATOM   3903 N  N   . LYS C 1 153 ? 20.256  -30.116 8.513   1.00 44.43  ? 153 LYS C N   1 
ATOM   3904 C  CA  . LYS C 1 153 ? 19.641  -28.823 8.820   1.00 39.71  ? 153 LYS C CA  1 
ATOM   3905 C  C   . LYS C 1 153 ? 20.690  -27.719 9.013   1.00 48.94  ? 153 LYS C C   1 
ATOM   3906 O  O   . LYS C 1 153 ? 20.457  -26.563 8.634   1.00 48.03  ? 153 LYS C O   1 
ATOM   3907 C  CB  . LYS C 1 153 ? 18.765  -28.944 10.059  1.00 36.64  ? 153 LYS C CB  1 
ATOM   3908 C  CG  . LYS C 1 153 ? 17.452  -29.671 9.834   1.00 39.17  ? 153 LYS C CG  1 
ATOM   3909 C  CD  . LYS C 1 153 ? 16.660  -29.709 11.128  1.00 36.31  ? 153 LYS C CD  1 
ATOM   3910 C  CE  . LYS C 1 153 ? 15.325  -30.395 10.956  1.00 38.22  ? 153 LYS C CE  1 
ATOM   3911 N  NZ  . LYS C 1 153 ? 14.629  -30.566 12.277  1.00 45.60  ? 153 LYS C NZ  1 
ATOM   3912 N  N   . ARG C 1 154 ? 21.853  -28.050 9.595   1.00 49.44  ? 154 ARG C N   1 
ATOM   3913 C  CA  . ARG C 1 154 ? 22.918  -27.053 9.730   1.00 50.99  ? 154 ARG C CA  1 
ATOM   3914 C  C   . ARG C 1 154 ? 23.536  -26.713 8.380   1.00 49.51  ? 154 ARG C C   1 
ATOM   3915 O  O   . ARG C 1 154 ? 23.594  -25.540 7.987   1.00 46.84  ? 154 ARG C O   1 
ATOM   3916 C  CB  . ARG C 1 154 ? 24.018  -27.534 10.681  1.00 50.65  ? 154 ARG C CB  1 
ATOM   3917 C  CG  . ARG C 1 154 ? 25.329  -26.739 10.495  1.00 46.55  ? 154 ARG C CG  1 
ATOM   3918 C  CD  . ARG C 1 154 ? 26.438  -27.190 11.440  1.00 48.22  ? 154 ARG C CD  1 
ATOM   3919 N  NE  . ARG C 1 154 ? 25.965  -27.144 12.815  1.00 54.27  ? 154 ARG C NE  1 
ATOM   3920 C  CZ  . ARG C 1 154 ? 25.748  -28.226 13.548  1.00 55.37  ? 154 ARG C CZ  1 
ATOM   3921 N  NH1 . ARG C 1 154 ? 25.996  -29.437 13.022  1.00 49.52  ? 154 ARG C NH1 1 
ATOM   3922 N  NH2 . ARG C 1 154 ? 25.286  -28.097 14.794  1.00 44.25  ? 154 ARG C NH2 1 
ATOM   3923 N  N   . CYS C 1 155 ? 24.021  -27.729 7.658   1.00 48.23  ? 155 CYS C N   1 
ATOM   3924 C  CA  . CYS C 1 155 ? 24.704  -27.517 6.383   1.00 53.60  ? 155 CYS C CA  1 
ATOM   3925 C  C   . CYS C 1 155 ? 23.788  -26.804 5.400   1.00 51.31  ? 155 CYS C C   1 
ATOM   3926 O  O   . CYS C 1 155 ? 24.224  -26.388 4.324   1.00 54.06  ? 155 CYS C O   1 
ATOM   3927 C  CB  . CYS C 1 155 ? 25.204  -28.844 5.787   1.00 48.50  ? 155 CYS C CB  1 
ATOM   3928 S  SG  . CYS C 1 155 ? 26.555  -29.731 6.692   1.00 72.37  ? 155 CYS C SG  1 
ATOM   3929 N  N   . GLY C 1 156 ? 22.534  -26.612 5.801   1.00 57.54  ? 156 GLY C N   1 
ATOM   3930 C  CA  . GLY C 1 156 ? 21.529  -25.983 4.984   1.00 54.34  ? 156 GLY C CA  1 
ATOM   3931 C  C   . GLY C 1 156 ? 20.859  -27.080 4.209   1.00 56.16  ? 156 GLY C C   1 
ATOM   3932 O  O   . GLY C 1 156 ? 21.490  -27.763 3.396   1.00 63.66  ? 156 GLY C O   1 
ATOM   3933 N  N   . PRO C 1 157 ? 19.567  -27.299 4.461   1.00 57.44  ? 157 PRO C N   1 
ATOM   3934 C  CA  . PRO C 1 157 ? 18.937  -28.559 4.028   1.00 53.51  ? 157 PRO C CA  1 
ATOM   3935 C  C   . PRO C 1 157 ? 18.640  -28.630 2.535   1.00 58.62  ? 157 PRO C C   1 
ATOM   3936 O  O   . PRO C 1 157 ? 18.224  -29.695 2.058   1.00 57.90  ? 157 PRO C O   1 
ATOM   3937 C  CB  . PRO C 1 157 ? 17.635  -28.605 4.855   1.00 52.24  ? 157 PRO C CB  1 
ATOM   3938 C  CG  . PRO C 1 157 ? 17.499  -27.192 5.510   1.00 50.99  ? 157 PRO C CG  1 
ATOM   3939 C  CD  . PRO C 1 157 ? 18.580  -26.317 4.936   1.00 52.54  ? 157 PRO C CD  1 
ATOM   3940 N  N   . THR C 1 158 ? 18.835  -27.547 1.784   1.00 58.51  ? 158 THR C N   1 
ATOM   3941 C  CA  . THR C 1 158 ? 18.641  -27.541 0.341   1.00 57.29  ? 158 THR C CA  1 
ATOM   3942 C  C   . THR C 1 158 ? 19.905  -27.009 -0.330  1.00 57.59  ? 158 THR C C   1 
ATOM   3943 O  O   . THR C 1 158 ? 20.806  -26.474 0.325   1.00 58.15  ? 158 THR C O   1 
ATOM   3944 C  CB  . THR C 1 158 ? 17.432  -26.677 -0.054  1.00 52.55  ? 158 THR C CB  1 
ATOM   3945 O  OG1 . THR C 1 158 ? 17.498  -25.428 0.645   1.00 62.24  ? 158 THR C OG1 1 
ATOM   3946 C  CG2 . THR C 1 158 ? 16.142  -27.372 0.331   1.00 49.42  ? 158 THR C CG2 1 
ATOM   3947 N  N   . GLY C 1 159 ? 19.962  -27.164 -1.651  1.00 56.20  ? 159 GLY C N   1 
ATOM   3948 C  CA  . GLY C 1 159 ? 21.000  -26.519 -2.437  1.00 44.30  ? 159 GLY C CA  1 
ATOM   3949 C  C   . GLY C 1 159 ? 22.372  -27.097 -2.185  1.00 43.64  ? 159 GLY C C   1 
ATOM   3950 O  O   . GLY C 1 159 ? 22.552  -28.310 -2.042  1.00 48.18  ? 159 GLY C O   1 
ATOM   3951 N  N   . LEU C 1 160 ? 23.359  -26.201 -2.119  1.00 48.93  ? 160 LEU C N   1 
ATOM   3952 C  CA  . LEU C 1 160 ? 24.754  -26.610 -1.998  1.00 46.90  ? 160 LEU C CA  1 
ATOM   3953 C  C   . LEU C 1 160 ? 25.009  -27.352 -0.695  1.00 43.70  ? 160 LEU C C   1 
ATOM   3954 O  O   . LEU C 1 160 ? 25.848  -28.257 -0.649  1.00 44.15  ? 160 LEU C O   1 
ATOM   3955 C  CB  . LEU C 1 160 ? 25.660  -25.378 -2.120  1.00 39.53  ? 160 LEU C CB  1 
ATOM   3956 C  CG  . LEU C 1 160 ? 27.153  -25.563 -1.838  1.00 56.72  ? 160 LEU C CG  1 
ATOM   3957 C  CD1 . LEU C 1 160 ? 27.827  -26.534 -2.828  1.00 56.64  ? 160 LEU C CD1 1 
ATOM   3958 C  CD2 . LEU C 1 160 ? 27.870  -24.219 -1.835  1.00 55.70  ? 160 LEU C CD2 1 
ATOM   3959 N  N   . GLY C 1 161 ? 24.295  -26.993 0.373   1.00 50.26  ? 161 GLY C N   1 
ATOM   3960 C  CA  . GLY C 1 161 ? 24.427  -27.733 1.613   1.00 42.62  ? 161 GLY C CA  1 
ATOM   3961 C  C   . GLY C 1 161 ? 23.942  -29.163 1.498   1.00 47.47  ? 161 GLY C C   1 
ATOM   3962 O  O   . GLY C 1 161 ? 24.470  -30.057 2.163   1.00 44.54  ? 161 GLY C O   1 
ATOM   3963 N  N   . GLU C 1 162 ? 22.942  -29.407 0.649   1.00 49.97  ? 162 GLU C N   1 
ATOM   3964 C  CA  . GLU C 1 162 ? 22.519  -30.781 0.401   1.00 48.08  ? 162 GLU C CA  1 
ATOM   3965 C  C   . GLU C 1 162 ? 23.562  -31.540 -0.414  1.00 44.80  ? 162 GLU C C   1 
ATOM   3966 O  O   . GLU C 1 162 ? 23.794  -32.729 -0.174  1.00 44.60  ? 162 GLU C O   1 
ATOM   3967 C  CB  . GLU C 1 162 ? 21.167  -30.794 -0.306  1.00 50.57  ? 162 GLU C CB  1 
ATOM   3968 C  CG  . GLU C 1 162 ? 20.471  -32.153 -0.277  1.00 50.54  ? 162 GLU C CG  1 
ATOM   3969 C  CD  . GLU C 1 162 ? 19.154  -32.138 -1.033  1.00 50.56  ? 162 GLU C CD  1 
ATOM   3970 O  OE1 . GLU C 1 162 ? 19.106  -31.545 -2.138  1.00 53.70  ? 162 GLU C OE1 1 
ATOM   3971 O  OE2 . GLU C 1 162 ? 18.160  -32.697 -0.507  1.00 46.09  ? 162 GLU C OE2 1 
ATOM   3972 N  N   . CYS C 1 163 ? 24.208  -30.866 -1.370  1.00 47.24  ? 163 CYS C N   1 
ATOM   3973 C  CA  . CYS C 1 163 ? 25.299  -31.491 -2.119  1.00 49.21  ? 163 CYS C CA  1 
ATOM   3974 C  C   . CYS C 1 163 ? 26.458  -31.848 -1.200  1.00 51.79  ? 163 CYS C C   1 
ATOM   3975 O  O   . CYS C 1 163 ? 26.961  -32.979 -1.233  1.00 50.04  ? 163 CYS C O   1 
ATOM   3976 C  CB  . CYS C 1 163 ? 25.787  -30.568 -3.242  1.00 51.10  ? 163 CYS C CB  1 
ATOM   3977 S  SG  . CYS C 1 163 ? 24.768  -30.532 -4.758  1.00 69.32  ? 163 CYS C SG  1 
ATOM   3978 N  N   . MET C 1 164 ? 26.906  -30.889 -0.373  1.00 45.76  ? 164 MET C N   1 
ATOM   3979 C  CA  . MET C 1 164 ? 28.038  -31.160 0.512   1.00 50.72  ? 164 MET C CA  1 
ATOM   3980 C  C   . MET C 1 164 ? 27.739  -32.324 1.450   1.00 54.43  ? 164 MET C C   1 
ATOM   3981 O  O   . MET C 1 164 ? 28.591  -33.199 1.659   1.00 47.88  ? 164 MET C O   1 
ATOM   3982 C  CB  . MET C 1 164 ? 28.417  -29.908 1.314   1.00 52.49  ? 164 MET C CB  1 
ATOM   3983 C  CG  . MET C 1 164 ? 28.913  -28.696 0.465   1.00 59.57  ? 164 MET C CG  1 
ATOM   3984 S  SD  . MET C 1 164 ? 29.792  -29.009 -1.118  1.00 89.29  ? 164 MET C SD  1 
ATOM   3985 C  CE  . MET C 1 164 ? 31.221  -29.977 -0.594  1.00 61.75  ? 164 MET C CE  1 
ATOM   3986 N  N   . PHE C 1 165 ? 26.525  -32.358 2.014   1.00 52.22  ? 165 PHE C N   1 
ATOM   3987 C  CA  . PHE C 1 165 ? 26.143  -33.470 2.878   1.00 45.60  ? 165 PHE C CA  1 
ATOM   3988 C  C   . PHE C 1 165 ? 26.186  -34.798 2.127   1.00 47.61  ? 165 PHE C C   1 
ATOM   3989 O  O   . PHE C 1 165 ? 26.630  -35.817 2.671   1.00 43.85  ? 165 PHE C O   1 
ATOM   3990 C  CB  . PHE C 1 165 ? 24.752  -33.229 3.448   1.00 46.04  ? 165 PHE C CB  1 
ATOM   3991 C  CG  . PHE C 1 165 ? 24.326  -34.276 4.412   1.00 46.93  ? 165 PHE C CG  1 
ATOM   3992 C  CD1 . PHE C 1 165 ? 24.642  -34.158 5.768   1.00 45.34  ? 165 PHE C CD1 1 
ATOM   3993 C  CD2 . PHE C 1 165 ? 23.630  -35.390 3.973   1.00 35.83  ? 165 PHE C CD2 1 
ATOM   3994 C  CE1 . PHE C 1 165 ? 24.264  -35.133 6.662   1.00 42.54  ? 165 PHE C CE1 1 
ATOM   3995 C  CE2 . PHE C 1 165 ? 23.245  -36.369 4.861   1.00 43.25  ? 165 PHE C CE2 1 
ATOM   3996 C  CZ  . PHE C 1 165 ? 23.559  -36.245 6.208   1.00 46.59  ? 165 PHE C CZ  1 
ATOM   3997 N  N   . ASP C 1 166 ? 25.732  -34.807 0.873   1.00 47.73  ? 166 ASP C N   1 
ATOM   3998 C  CA  . ASP C 1 166 ? 25.797  -36.026 0.072   1.00 45.00  ? 166 ASP C CA  1 
ATOM   3999 C  C   . ASP C 1 166 ? 27.228  -36.540 -0.057  1.00 51.73  ? 166 ASP C C   1 
ATOM   4000 O  O   . ASP C 1 166 ? 27.481  -37.737 0.124   1.00 54.46  ? 166 ASP C O   1 
ATOM   4001 C  CB  . ASP C 1 166 ? 25.198  -35.773 -1.306  1.00 42.75  ? 166 ASP C CB  1 
ATOM   4002 C  CG  . ASP C 1 166 ? 24.847  -37.047 -2.024  1.00 44.50  ? 166 ASP C CG  1 
ATOM   4003 O  OD1 . ASP C 1 166 ? 23.872  -37.685 -1.600  1.00 40.36  ? 166 ASP C OD1 1 
ATOM   4004 O  OD2 . ASP C 1 166 ? 25.526  -37.398 -3.019  1.00 49.66  ? 166 ASP C OD2 1 
ATOM   4005 N  N   . LYS C 1 167 ? 28.180  -35.646 -0.373  1.00 48.86  ? 167 LYS C N   1 
ATOM   4006 C  CA  . LYS C 1 167 ? 29.559  -36.070 -0.622  1.00 52.16  ? 167 LYS C CA  1 
ATOM   4007 C  C   . LYS C 1 167 ? 30.183  -36.713 0.610   1.00 54.54  ? 167 LYS C C   1 
ATOM   4008 O  O   . LYS C 1 167 ? 30.940  -37.683 0.495   1.00 60.84  ? 167 LYS C O   1 
ATOM   4009 C  CB  . LYS C 1 167 ? 30.406  -34.880 -1.085  1.00 54.61  ? 167 LYS C CB  1 
ATOM   4010 C  CG  . LYS C 1 167 ? 31.610  -35.259 -1.948  1.00 58.63  ? 167 LYS C CG  1 
ATOM   4011 C  CD  . LYS C 1 167 ? 32.909  -35.365 -1.150  1.00 66.41  ? 167 LYS C CD  1 
ATOM   4012 C  CE  . LYS C 1 167 ? 33.949  -36.221 -1.880  1.00 66.18  ? 167 LYS C CE  1 
ATOM   4013 N  NZ  . LYS C 1 167 ? 33.547  -37.662 -2.063  1.00 67.80  ? 167 LYS C NZ  1 
ATOM   4014 N  N   . GLU C 1 168 ? 29.881  -36.191 1.799   1.00 53.78  ? 168 GLU C N   1 
ATOM   4015 C  CA  . GLU C 1 168 ? 30.453  -36.746 3.018   1.00 54.20  ? 168 GLU C CA  1 
ATOM   4016 C  C   . GLU C 1 168 ? 29.671  -37.923 3.553   1.00 56.10  ? 168 GLU C C   1 
ATOM   4017 O  O   . GLU C 1 168 ? 30.124  -38.571 4.499   1.00 56.41  ? 168 GLU C O   1 
ATOM   4018 C  CB  . GLU C 1 168 ? 30.566  -35.668 4.085   1.00 49.51  ? 168 GLU C CB  1 
ATOM   4019 C  CG  . GLU C 1 168 ? 31.304  -34.455 3.558   1.00 64.96  ? 168 GLU C CG  1 
ATOM   4020 C  CD  . GLU C 1 168 ? 31.204  -33.259 4.481   1.00 78.26  ? 168 GLU C CD  1 
ATOM   4021 O  OE1 . GLU C 1 168 ? 30.586  -33.389 5.564   1.00 84.68  ? 168 GLU C OE1 1 
ATOM   4022 O  OE2 . GLU C 1 168 ? 31.734  -32.183 4.113   1.00 78.46  ? 168 GLU C OE2 1 
ATOM   4023 N  N   . LEU C 1 169 ? 28.492  -38.180 3.003   1.00 60.80  ? 169 LEU C N   1 
ATOM   4024 C  CA  . LEU C 1 169 ? 27.865  -39.481 3.167   1.00 58.22  ? 169 LEU C CA  1 
ATOM   4025 C  C   . LEU C 1 169 ? 28.626  -40.528 2.367   1.00 62.11  ? 169 LEU C C   1 
ATOM   4026 O  O   . LEU C 1 169 ? 29.098  -41.533 2.916   1.00 62.90  ? 169 LEU C O   1 
ATOM   4027 C  CB  . LEU C 1 169 ? 26.416  -39.393 2.701   1.00 53.39  ? 169 LEU C CB  1 
ATOM   4028 C  CG  . LEU C 1 169 ? 25.296  -40.128 3.409   1.00 49.57  ? 169 LEU C CG  1 
ATOM   4029 C  CD1 . LEU C 1 169 ? 25.515  -40.133 4.905   1.00 44.49  ? 169 LEU C CD1 1 
ATOM   4030 C  CD2 . LEU C 1 169 ? 24.006  -39.420 3.039   1.00 46.14  ? 169 LEU C CD2 1 
ATOM   4031 N  N   . ASN C 1 170 ? 28.785  -40.276 1.068   1.00 68.27  ? 170 ASN C N   1 
ATOM   4032 C  CA  . ASN C 1 170 ? 29.409  -41.200 0.124   1.00 74.87  ? 170 ASN C CA  1 
ATOM   4033 C  C   . ASN C 1 170 ? 30.844  -41.560 0.496   1.00 81.19  ? 170 ASN C C   1 
ATOM   4034 O  O   . ASN C 1 170 ? 31.555  -40.785 1.151   1.00 83.28  ? 170 ASN C O   1 
ATOM   4035 C  CB  . ASN C 1 170 ? 29.384  -40.608 -1.290  1.00 68.05  ? 170 ASN C CB  1 
ATOM   4036 C  CG  . ASN C 1 170 ? 29.125  -41.668 -2.360  1.00 72.40  ? 170 ASN C CG  1 
ATOM   4037 O  OD1 . ASN C 1 170 ? 29.161  -42.868 -2.078  1.00 74.67  ? 170 ASN C OD1 1 
ATOM   4038 N  ND2 . ASN C 1 170 ? 28.888  -41.229 -3.595  1.00 65.62  ? 170 ASN C ND2 1 
ATOM   4039 O  OXT . ASN C 1 170 ? 31.302  -42.648 0.131   1.00 76.03  ? 170 ASN C OXT 1 
ATOM   4040 N  N   . ALA D 1 2   ? 61.700  -31.514 56.360  1.00 94.70  ? 2   ALA D N   1 
ATOM   4041 C  CA  . ALA D 1 2   ? 61.924  -31.301 54.932  1.00 102.35 ? 2   ALA D CA  1 
ATOM   4042 C  C   . ALA D 1 2   ? 61.952  -32.637 54.189  1.00 107.84 ? 2   ALA D C   1 
ATOM   4043 O  O   . ALA D 1 2   ? 61.371  -33.623 54.652  1.00 100.01 ? 2   ALA D O   1 
ATOM   4044 C  CB  . ALA D 1 2   ? 63.224  -30.525 54.694  1.00 92.48  ? 2   ALA D CB  1 
ATOM   4045 N  N   . SER D 1 3   ? 62.637  -32.665 53.044  1.00 107.86 ? 3   SER D N   1 
ATOM   4046 C  CA  . SER D 1 3   ? 62.682  -33.837 52.181  1.00 99.08  ? 3   SER D CA  1 
ATOM   4047 C  C   . SER D 1 3   ? 64.129  -34.258 51.937  1.00 95.90  ? 3   SER D C   1 
ATOM   4048 O  O   . SER D 1 3   ? 65.076  -33.493 52.155  1.00 92.98  ? 3   SER D O   1 
ATOM   4049 C  CB  . SER D 1 3   ? 61.967  -33.567 50.834  1.00 92.55  ? 3   SER D CB  1 
ATOM   4050 O  OG  . SER D 1 3   ? 61.496  -34.762 50.218  1.00 84.48  ? 3   SER D OG  1 
ATOM   4051 N  N   . GLN D 1 4   ? 64.281  -35.507 51.489  1.00 93.84  ? 4   GLN D N   1 
ATOM   4052 C  CA  . GLN D 1 4   ? 65.574  -36.001 51.018  1.00 91.71  ? 4   GLN D CA  1 
ATOM   4053 C  C   . GLN D 1 4   ? 66.032  -35.255 49.771  1.00 94.31  ? 4   GLN D C   1 
ATOM   4054 O  O   . GLN D 1 4   ? 67.174  -34.778 49.692  1.00 90.31  ? 4   GLN D O   1 
ATOM   4055 C  CB  . GLN D 1 4   ? 65.465  -37.490 50.706  1.00 82.98  ? 4   GLN D CB  1 
ATOM   4056 C  CG  . GLN D 1 4   ? 66.368  -38.368 51.510  1.00 82.85  ? 4   GLN D CG  1 
ATOM   4057 C  CD  . GLN D 1 4   ? 66.255  -39.818 51.093  1.00 70.97  ? 4   GLN D CD  1 
ATOM   4058 O  OE1 . GLN D 1 4   ? 65.252  -40.242 50.499  1.00 56.92  ? 4   GLN D OE1 1 
ATOM   4059 N  NE2 . GLN D 1 4   ? 67.290  -40.590 51.399  1.00 69.36  ? 4   GLN D NE2 1 
ATOM   4060 N  N   . VAL D 1 5   ? 65.156  -35.170 48.775  1.00 91.15  ? 5   VAL D N   1 
ATOM   4061 C  CA  . VAL D 1 5   ? 65.503  -34.644 47.467  1.00 93.25  ? 5   VAL D CA  1 
ATOM   4062 C  C   . VAL D 1 5   ? 65.215  -33.142 47.372  1.00 94.25  ? 5   VAL D C   1 
ATOM   4063 O  O   . VAL D 1 5   ? 65.162  -32.591 46.267  1.00 95.51  ? 5   VAL D O   1 
ATOM   4064 C  CB  . VAL D 1 5   ? 64.794  -35.430 46.349  1.00 83.81  ? 5   VAL D CB  1 
ATOM   4065 C  CG1 . VAL D 1 5   ? 65.184  -36.898 46.424  1.00 66.84  ? 5   VAL D CG1 1 
ATOM   4066 C  CG2 . VAL D 1 5   ? 63.268  -35.269 46.432  1.00 77.02  ? 5   VAL D CG2 1 
ATOM   4067 N  N   . ARG D 1 6   ? 65.044  -32.464 48.512  1.00 90.72  ? 6   ARG D N   1 
ATOM   4068 C  CA  . ARG D 1 6   ? 64.723  -31.040 48.519  1.00 90.57  ? 6   ARG D CA  1 
ATOM   4069 C  C   . ARG D 1 6   ? 66.000  -30.204 48.588  1.00 94.31  ? 6   ARG D C   1 
ATOM   4070 O  O   . ARG D 1 6   ? 66.838  -30.400 49.478  1.00 93.41  ? 6   ARG D O   1 
ATOM   4071 C  CB  . ARG D 1 6   ? 63.782  -30.695 49.676  1.00 82.25  ? 6   ARG D CB  1 
ATOM   4072 C  CG  . ARG D 1 6   ? 63.318  -29.254 49.632  1.00 84.69  ? 6   ARG D CG  1 
ATOM   4073 C  CD  . ARG D 1 6   ? 62.217  -28.961 50.630  1.00 85.50  ? 6   ARG D CD  1 
ATOM   4074 N  NE  . ARG D 1 6   ? 61.349  -27.886 50.140  1.00 87.24  ? 6   ARG D NE  1 
ATOM   4075 C  CZ  . ARG D 1 6   ? 60.020  -27.944 50.077  1.00 78.95  ? 6   ARG D CZ  1 
ATOM   4076 N  NH1 . ARG D 1 6   ? 59.333  -26.909 49.613  1.00 77.94  ? 6   ARG D NH1 1 
ATOM   4077 N  NH2 . ARG D 1 6   ? 59.374  -29.030 50.478  1.00 69.13  ? 6   ARG D NH2 1 
ATOM   4078 N  N   . GLN D 1 7   ? 66.126  -29.258 47.645  1.00 93.64  ? 7   GLN D N   1 
ATOM   4079 C  CA  . GLN D 1 7   ? 67.374  -28.518 47.429  1.00 96.07  ? 7   GLN D CA  1 
ATOM   4080 C  C   . GLN D 1 7   ? 67.011  -27.196 46.745  1.00 95.79  ? 7   GLN D C   1 
ATOM   4081 O  O   . GLN D 1 7   ? 66.796  -27.178 45.528  1.00 93.83  ? 7   GLN D O   1 
ATOM   4082 C  CB  . GLN D 1 7   ? 68.340  -29.330 46.572  1.00 92.48  ? 7   GLN D CB  1 
ATOM   4083 C  CG  . GLN D 1 7   ? 69.571  -29.900 47.267  1.00 87.13  ? 7   GLN D CG  1 
ATOM   4084 C  CD  . GLN D 1 7   ? 70.770  -30.007 46.318  1.00 86.90  ? 7   GLN D CD  1 
ATOM   4085 O  OE1 . GLN D 1 7   ? 70.660  -30.560 45.218  1.00 85.55  ? 7   GLN D OE1 1 
ATOM   4086 N  NE2 . GLN D 1 7   ? 71.919  -29.478 46.743  1.00 74.95  ? 7   GLN D NE2 1 
ATOM   4087 N  N   . ASN D 1 8   ? 66.960  -26.105 47.521  1.00 98.04  ? 8   ASN D N   1 
ATOM   4088 C  CA  . ASN D 1 8   ? 66.639  -24.773 46.989  1.00 99.66  ? 8   ASN D CA  1 
ATOM   4089 C  C   . ASN D 1 8   ? 65.209  -24.754 46.425  1.00 98.66  ? 8   ASN D C   1 
ATOM   4090 O  O   . ASN D 1 8   ? 64.975  -24.495 45.236  1.00 94.83  ? 8   ASN D O   1 
ATOM   4091 C  CB  . ASN D 1 8   ? 67.688  -24.350 45.934  1.00 96.88  ? 8   ASN D CB  1 
ATOM   4092 C  CG  . ASN D 1 8   ? 67.541  -22.891 45.455  1.00 94.33  ? 8   ASN D CG  1 
ATOM   4093 O  OD1 . ASN D 1 8   ? 67.099  -22.011 46.194  1.00 94.89  ? 8   ASN D OD1 1 
ATOM   4094 N  ND2 . ASN D 1 8   ? 67.941  -22.642 44.204  1.00 85.51  ? 8   ASN D ND2 1 
ATOM   4095 N  N   . TYR D 1 9   ? 64.244  -25.050 47.308  1.00 89.70  ? 9   TYR D N   1 
ATOM   4096 C  CA  . TYR D 1 9   ? 62.827  -25.136 46.939  1.00 91.95  ? 9   TYR D CA  1 
ATOM   4097 C  C   . TYR D 1 9   ? 61.977  -24.380 47.961  1.00 85.22  ? 9   TYR D C   1 
ATOM   4098 O  O   . TYR D 1 9   ? 61.764  -24.865 49.079  1.00 83.64  ? 9   TYR D O   1 
ATOM   4099 C  CB  . TYR D 1 9   ? 62.374  -26.599 46.820  1.00 87.34  ? 9   TYR D CB  1 
ATOM   4100 C  CG  . TYR D 1 9   ? 61.072  -26.798 46.052  1.00 84.44  ? 9   TYR D CG  1 
ATOM   4101 C  CD1 . TYR D 1 9   ? 60.852  -26.158 44.830  1.00 79.48  ? 9   TYR D CD1 1 
ATOM   4102 C  CD2 . TYR D 1 9   ? 60.068  -27.635 46.546  1.00 80.60  ? 9   TYR D CD2 1 
ATOM   4103 C  CE1 . TYR D 1 9   ? 59.667  -26.340 44.127  1.00 75.01  ? 9   TYR D CE1 1 
ATOM   4104 C  CE2 . TYR D 1 9   ? 58.876  -27.822 45.850  1.00 72.87  ? 9   TYR D CE2 1 
ATOM   4105 C  CZ  . TYR D 1 9   ? 58.683  -27.172 44.643  1.00 73.50  ? 9   TYR D CZ  1 
ATOM   4106 O  OH  . TYR D 1 9   ? 57.504  -27.351 43.951  1.00 68.00  ? 9   TYR D OH  1 
ATOM   4107 N  N   . HIS D 1 10  ? 61.469  -23.211 47.565  1.00 81.80  ? 10  HIS D N   1 
ATOM   4108 C  CA  . HIS D 1 10  ? 60.701  -22.339 48.450  1.00 86.71  ? 10  HIS D CA  1 
ATOM   4109 C  C   . HIS D 1 10  ? 59.286  -22.889 48.696  1.00 82.62  ? 10  HIS D C   1 
ATOM   4110 O  O   . HIS D 1 10  ? 58.717  -23.630 47.887  1.00 79.06  ? 10  HIS D O   1 
ATOM   4111 C  CB  . HIS D 1 10  ? 60.626  -20.919 47.860  1.00 80.31  ? 10  HIS D CB  1 
ATOM   4112 C  CG  . HIS D 1 10  ? 60.336  -19.845 48.871  1.00 82.98  ? 10  HIS D CG  1 
ATOM   4113 N  ND1 . HIS D 1 10  ? 59.121  -19.729 49.518  1.00 83.04  ? 10  HIS D ND1 1 
ATOM   4114 C  CD2 . HIS D 1 10  ? 61.101  -18.828 49.333  1.00 82.00  ? 10  HIS D CD2 1 
ATOM   4115 C  CE1 . HIS D 1 10  ? 59.155  -18.697 50.341  1.00 79.00  ? 10  HIS D CE1 1 
ATOM   4116 N  NE2 . HIS D 1 10  ? 60.345  -18.132 50.248  1.00 84.85  ? 10  HIS D NE2 1 
ATOM   4117 N  N   . GLU D 1 11  ? 58.713  -22.489 49.833  1.00 79.66  ? 11  GLU D N   1 
ATOM   4118 C  CA  . GLU D 1 11  ? 57.390  -22.968 50.231  1.00 76.99  ? 11  GLU D CA  1 
ATOM   4119 C  C   . GLU D 1 11  ? 56.287  -22.457 49.300  1.00 81.19  ? 11  GLU D C   1 
ATOM   4120 O  O   . GLU D 1 11  ? 55.392  -23.216 48.906  1.00 76.06  ? 11  GLU D O   1 
ATOM   4121 C  CB  . GLU D 1 11  ? 57.114  -22.544 51.671  1.00 76.92  ? 11  GLU D CB  1 
ATOM   4122 C  CG  . GLU D 1 11  ? 55.663  -22.227 51.948  1.00 83.63  ? 11  GLU D CG  1 
ATOM   4123 C  CD  . GLU D 1 11  ? 55.492  -21.405 53.193  1.00 91.66  ? 11  GLU D CD  1 
ATOM   4124 O  OE1 . GLU D 1 11  ? 54.349  -21.305 53.687  1.00 94.82  ? 11  GLU D OE1 1 
ATOM   4125 O  OE2 . GLU D 1 11  ? 56.508  -20.859 53.675  1.00 95.56  ? 11  GLU D OE2 1 
ATOM   4126 N  N   . ASP D 1 12  ? 56.303  -21.164 48.966  1.00 84.02  ? 12  ASP D N   1 
ATOM   4127 C  CA  . ASP D 1 12  ? 55.215  -20.628 48.156  1.00 82.91  ? 12  ASP D CA  1 
ATOM   4128 C  C   . ASP D 1 12  ? 55.374  -20.946 46.671  1.00 73.99  ? 12  ASP D C   1 
ATOM   4129 O  O   . ASP D 1 12  ? 54.427  -20.725 45.908  1.00 71.64  ? 12  ASP D O   1 
ATOM   4130 C  CB  . ASP D 1 12  ? 55.073  -19.114 48.376  1.00 81.19  ? 12  ASP D CB  1 
ATOM   4131 C  CG  . ASP D 1 12  ? 56.402  -18.385 48.302  1.00 88.78  ? 12  ASP D CG  1 
ATOM   4132 O  OD1 . ASP D 1 12  ? 57.394  -19.006 47.861  1.00 86.70  ? 12  ASP D OD1 1 
ATOM   4133 O  OD2 . ASP D 1 12  ? 56.457  -17.191 48.676  1.00 93.01  ? 12  ASP D OD2 1 
ATOM   4134 N  N   . CYS D 1 13  ? 56.539  -21.449 46.240  1.00 65.88  ? 13  CYS D N   1 
ATOM   4135 C  CA  . CYS D 1 13  ? 56.591  -22.163 44.966  1.00 69.30  ? 13  CYS D CA  1 
ATOM   4136 C  C   . CYS D 1 13  ? 55.780  -23.454 45.042  1.00 68.97  ? 13  CYS D C   1 
ATOM   4137 O  O   . CYS D 1 13  ? 55.067  -23.808 44.096  1.00 66.41  ? 13  CYS D O   1 
ATOM   4138 C  CB  . CYS D 1 13  ? 58.040  -22.473 44.556  1.00 68.50  ? 13  CYS D CB  1 
ATOM   4139 S  SG  . CYS D 1 13  ? 59.161  -21.066 44.135  1.00 73.66  ? 13  CYS D SG  1 
ATOM   4140 N  N   . GLU D 1 14  ? 55.875  -24.164 46.167  1.00 69.38  ? 14  GLU D N   1 
ATOM   4141 C  CA  . GLU D 1 14  ? 55.138  -25.410 46.332  1.00 64.17  ? 14  GLU D CA  1 
ATOM   4142 C  C   . GLU D 1 14  ? 53.632  -25.170 46.310  1.00 62.41  ? 14  GLU D C   1 
ATOM   4143 O  O   . GLU D 1 14  ? 52.881  -25.964 45.724  1.00 54.33  ? 14  GLU D O   1 
ATOM   4144 C  CB  . GLU D 1 14  ? 55.564  -26.102 47.631  1.00 62.33  ? 14  GLU D CB  1 
ATOM   4145 C  CG  . GLU D 1 14  ? 54.439  -26.858 48.337  1.00 64.47  ? 14  GLU D CG  1 
ATOM   4146 C  CD  . GLU D 1 14  ? 54.945  -27.813 49.402  1.00 66.83  ? 14  GLU D CD  1 
ATOM   4147 O  OE1 . GLU D 1 14  ? 56.172  -27.809 49.654  1.00 65.00  ? 14  GLU D OE1 1 
ATOM   4148 O  OE2 . GLU D 1 14  ? 54.120  -28.588 49.956  1.00 63.36  ? 14  GLU D OE2 1 
ATOM   4149 N  N   . ALA D 1 15  ? 53.172  -24.078 46.939  1.00 58.28  ? 15  ALA D N   1 
ATOM   4150 C  CA  . ALA D 1 15  ? 51.741  -23.787 46.984  1.00 51.15  ? 15  ALA D CA  1 
ATOM   4151 C  C   . ALA D 1 15  ? 51.227  -23.241 45.658  1.00 57.13  ? 15  ALA D C   1 
ATOM   4152 O  O   . ALA D 1 15  ? 50.037  -23.394 45.344  1.00 58.05  ? 15  ALA D O   1 
ATOM   4153 C  CB  . ALA D 1 15  ? 51.434  -22.788 48.094  1.00 45.83  ? 15  ALA D CB  1 
ATOM   4154 N  N   . SER D 1 16  ? 52.092  -22.583 44.883  1.00 51.63  ? 16  SER D N   1 
ATOM   4155 C  CA  . SER D 1 16  ? 51.682  -22.099 43.571  1.00 53.24  ? 16  SER D CA  1 
ATOM   4156 C  C   . SER D 1 16  ? 51.607  -23.250 42.583  1.00 54.74  ? 16  SER D C   1 
ATOM   4157 O  O   . SER D 1 16  ? 50.693  -23.300 41.749  1.00 49.58  ? 16  SER D O   1 
ATOM   4158 C  CB  . SER D 1 16  ? 52.648  -21.021 43.063  1.00 52.45  ? 16  SER D CB  1 
ATOM   4159 O  OG  . SER D 1 16  ? 52.526  -19.807 43.792  1.00 63.11  ? 16  SER D OG  1 
ATOM   4160 N  N   . ILE D 1 17  ? 52.566  -24.179 42.677  1.00 51.94  ? 17  ILE D N   1 
ATOM   4161 C  CA  . ILE D 1 17  ? 52.516  -25.399 41.883  1.00 46.94  ? 17  ILE D CA  1 
ATOM   4162 C  C   . ILE D 1 17  ? 51.185  -26.113 42.085  1.00 47.74  ? 17  ILE D C   1 
ATOM   4163 O  O   . ILE D 1 17  ? 50.553  -26.540 41.114  1.00 46.39  ? 17  ILE D O   1 
ATOM   4164 C  CB  . ILE D 1 17  ? 53.710  -26.309 42.225  1.00 50.78  ? 17  ILE D CB  1 
ATOM   4165 C  CG1 . ILE D 1 17  ? 55.012  -25.737 41.661  1.00 50.41  ? 17  ILE D CG1 1 
ATOM   4166 C  CG2 . ILE D 1 17  ? 53.488  -27.708 41.671  1.00 46.22  ? 17  ILE D CG2 1 
ATOM   4167 C  CD1 . ILE D 1 17  ? 55.168  -25.995 40.182  1.00 60.04  ? 17  ILE D CD1 1 
ATOM   4168 N  N   . ASN D 1 18  ? 50.726  -26.237 43.343  1.00 44.59  ? 18  ASN D N   1 
ATOM   4169 C  CA  . ASN D 1 18  ? 49.436  -26.878 43.602  1.00 39.56  ? 18  ASN D CA  1 
ATOM   4170 C  C   . ASN D 1 18  ? 48.283  -26.075 42.999  1.00 42.86  ? 18  ASN D C   1 
ATOM   4171 O  O   . ASN D 1 18  ? 47.338  -26.647 42.441  1.00 38.76  ? 18  ASN D O   1 
ATOM   4172 C  CB  . ASN D 1 18  ? 49.223  -27.057 45.102  1.00 38.64  ? 18  ASN D CB  1 
ATOM   4173 C  CG  . ASN D 1 18  ? 50.070  -28.189 45.700  1.00 46.55  ? 18  ASN D CG  1 
ATOM   4174 O  OD1 . ASN D 1 18  ? 50.379  -29.182 45.038  1.00 45.69  ? 18  ASN D OD1 1 
ATOM   4175 N  ND2 . ASN D 1 18  ? 50.426  -28.047 46.969  1.00 44.26  ? 18  ASN D ND2 1 
ATOM   4176 N  N   . LYS D 1 19  ? 48.341  -24.748 43.102  1.00 47.78  ? 19  LYS D N   1 
ATOM   4177 C  CA  . LYS D 1 19  ? 47.347  -23.925 42.426  1.00 46.65  ? 19  LYS D CA  1 
ATOM   4178 C  C   . LYS D 1 19  ? 47.373  -24.165 40.919  1.00 43.66  ? 19  LYS D C   1 
ATOM   4179 O  O   . LYS D 1 19  ? 46.316  -24.239 40.280  1.00 42.11  ? 19  LYS D O   1 
ATOM   4180 C  CB  . LYS D 1 19  ? 47.560  -22.447 42.768  1.00 51.32  ? 19  LYS D CB  1 
ATOM   4181 C  CG  . LYS D 1 19  ? 46.651  -21.513 41.981  1.00 60.16  ? 19  LYS D CG  1 
ATOM   4182 C  CD  . LYS D 1 19  ? 46.289  -20.245 42.740  1.00 65.00  ? 19  LYS D CD  1 
ATOM   4183 C  CE  . LYS D 1 19  ? 45.004  -19.611 42.178  1.00 75.22  ? 19  LYS D CE  1 
ATOM   4184 N  NZ  . LYS D 1 19  ? 43.835  -19.654 43.126  1.00 78.58  ? 19  LYS D NZ  1 
ATOM   4185 N  N   . GLN D 1 20  ? 48.561  -24.359 40.341  1.00 38.85  ? 20  GLN D N   1 
ATOM   4186 C  CA  . GLN D 1 20  ? 48.634  -24.640 38.905  1.00 40.33  ? 20  GLN D CA  1 
ATOM   4187 C  C   . GLN D 1 20  ? 48.076  -26.027 38.567  1.00 42.92  ? 20  GLN D C   1 
ATOM   4188 O  O   . GLN D 1 20  ? 47.409  -26.202 37.538  1.00 41.51  ? 20  GLN D O   1 
ATOM   4189 C  CB  . GLN D 1 20  ? 50.077  -24.500 38.413  1.00 43.95  ? 20  GLN D CB  1 
ATOM   4190 C  CG  . GLN D 1 20  ? 50.210  -24.327 36.900  1.00 46.48  ? 20  GLN D CG  1 
ATOM   4191 C  CD  . GLN D 1 20  ? 49.504  -23.071 36.388  1.00 50.44  ? 20  GLN D CD  1 
ATOM   4192 O  OE1 . GLN D 1 20  ? 49.313  -22.097 37.128  1.00 48.61  ? 20  GLN D OE1 1 
ATOM   4193 N  NE2 . GLN D 1 20  ? 49.088  -23.103 35.129  1.00 48.24  ? 20  GLN D NE2 1 
ATOM   4194 N  N   . ILE D 1 21  ? 48.328  -27.023 39.420  1.00 39.15  ? 21  ILE D N   1 
ATOM   4195 C  CA  . ILE D 1 21  ? 47.767  -28.355 39.205  1.00 38.33  ? 21  ILE D CA  1 
ATOM   4196 C  C   . ILE D 1 21  ? 46.246  -28.291 39.125  1.00 37.29  ? 21  ILE D C   1 
ATOM   4197 O  O   . ILE D 1 21  ? 45.628  -28.849 38.207  1.00 34.84  ? 21  ILE D O   1 
ATOM   4198 C  CB  . ILE D 1 21  ? 48.219  -29.318 40.314  1.00 38.06  ? 21  ILE D CB  1 
ATOM   4199 C  CG1 . ILE D 1 21  ? 49.737  -29.555 40.219  1.00 38.26  ? 21  ILE D CG1 1 
ATOM   4200 C  CG2 . ILE D 1 21  ? 47.384  -30.618 40.231  1.00 29.99  ? 21  ILE D CG2 1 
ATOM   4201 C  CD1 . ILE D 1 21  ? 50.348  -30.301 41.409  1.00 38.19  ? 21  ILE D CD1 1 
ATOM   4202 N  N   . ASN D 1 22  ? 45.620  -27.600 40.082  1.00 37.97  ? 22  ASN D N   1 
ATOM   4203 C  CA  . ASN D 1 22  ? 44.166  -27.495 40.074  1.00 34.68  ? 22  ASN D CA  1 
ATOM   4204 C  C   . ASN D 1 22  ? 43.676  -26.767 38.830  1.00 36.32  ? 22  ASN D C   1 
ATOM   4205 O  O   . ASN D 1 22  ? 42.658  -27.151 38.236  1.00 35.34  ? 22  ASN D O   1 
ATOM   4206 C  CB  . ASN D 1 22  ? 43.656  -26.785 41.329  1.00 30.67  ? 22  ASN D CB  1 
ATOM   4207 C  CG  . ASN D 1 22  ? 42.152  -26.950 41.489  1.00 37.67  ? 22  ASN D CG  1 
ATOM   4208 O  OD1 . ASN D 1 22  ? 41.374  -26.070 41.105  1.00 36.85  ? 22  ASN D OD1 1 
ATOM   4209 N  ND2 . ASN D 1 22  ? 41.730  -28.114 41.998  1.00 34.55  ? 22  ASN D ND2 1 
ATOM   4210 N  N   . MET D 1 23  ? 44.397  -25.724 38.412  1.00 36.38  ? 23  MET D N   1 
ATOM   4211 C  CA  . MET D 1 23  ? 44.000  -24.986 37.216  1.00 37.04  ? 23  MET D CA  1 
ATOM   4212 C  C   . MET D 1 23  ? 44.035  -25.864 35.969  1.00 39.96  ? 23  MET D C   1 
ATOM   4213 O  O   . MET D 1 23  ? 43.109  -25.829 35.146  1.00 35.53  ? 23  MET D O   1 
ATOM   4214 C  CB  . MET D 1 23  ? 44.885  -23.758 37.023  1.00 32.96  ? 23  MET D CB  1 
ATOM   4215 C  CG  . MET D 1 23  ? 44.382  -22.930 35.861  1.00 47.04  ? 23  MET D CG  1 
ATOM   4216 S  SD  . MET D 1 23  ? 42.934  -21.939 36.196  1.00 64.54  ? 23  MET D SD  1 
ATOM   4217 C  CE  . MET D 1 23  ? 41.633  -23.178 36.317  1.00 58.72  ? 23  MET D CE  1 
ATOM   4218 N  N   . GLU D 1 24  ? 45.112  -26.633 35.788  1.00 34.37  ? 24  GLU D N   1 
ATOM   4219 C  CA  . GLU D 1 24  ? 45.168  -27.524 34.636  1.00 39.28  ? 24  GLU D CA  1 
ATOM   4220 C  C   . GLU D 1 24  ? 44.052  -28.557 34.696  1.00 36.20  ? 24  GLU D C   1 
ATOM   4221 O  O   . GLU D 1 24  ? 43.474  -28.921 33.662  1.00 36.66  ? 24  GLU D O   1 
ATOM   4222 C  CB  . GLU D 1 24  ? 46.529  -28.232 34.545  1.00 41.50  ? 24  GLU D CB  1 
ATOM   4223 C  CG  . GLU D 1 24  ? 47.752  -27.320 34.619  1.00 44.77  ? 24  GLU D CG  1 
ATOM   4224 C  CD  . GLU D 1 24  ? 47.933  -26.463 33.391  1.00 60.36  ? 24  GLU D CD  1 
ATOM   4225 O  OE1 . GLU D 1 24  ? 48.850  -25.607 33.393  1.00 66.46  ? 24  GLU D OE1 1 
ATOM   4226 O  OE2 . GLU D 1 24  ? 47.167  -26.648 32.416  1.00 61.63  ? 24  GLU D OE2 1 
ATOM   4227 N  N   . LEU D 1 25  ? 43.756  -29.070 35.893  1.00 33.49  ? 25  LEU D N   1 
ATOM   4228 C  CA  . LEU D 1 25  ? 42.691  -30.057 36.002  1.00 32.15  ? 25  LEU D CA  1 
ATOM   4229 C  C   . LEU D 1 25  ? 41.354  -29.410 35.698  1.00 33.98  ? 25  LEU D C   1 
ATOM   4230 O  O   . LEU D 1 25  ? 40.501  -30.004 35.030  1.00 33.33  ? 25  LEU D O   1 
ATOM   4231 C  CB  . LEU D 1 25  ? 42.700  -30.686 37.393  1.00 34.98  ? 25  LEU D CB  1 
ATOM   4232 C  CG  . LEU D 1 25  ? 43.869  -31.632 37.644  1.00 34.56  ? 25  LEU D CG  1 
ATOM   4233 C  CD1 . LEU D 1 25  ? 43.897  -32.088 39.105  1.00 34.44  ? 25  LEU D CD1 1 
ATOM   4234 C  CD2 . LEU D 1 25  ? 43.834  -32.840 36.695  1.00 29.54  ? 25  LEU D CD2 1 
ATOM   4235 N  N   . TYR D 1 26  ? 41.183  -28.164 36.139  1.00 34.67  ? 26  TYR D N   1 
ATOM   4236 C  CA  . TYR D 1 26  ? 40.001  -27.393 35.782  1.00 36.37  ? 26  TYR D CA  1 
ATOM   4237 C  C   . TYR D 1 26  ? 39.853  -27.286 34.264  1.00 36.49  ? 26  TYR D C   1 
ATOM   4238 O  O   . TYR D 1 26  ? 38.840  -27.725 33.694  1.00 33.52  ? 26  TYR D O   1 
ATOM   4239 C  CB  . TYR D 1 26  ? 40.073  -26.005 36.426  1.00 36.29  ? 26  TYR D CB  1 
ATOM   4240 C  CG  . TYR D 1 26  ? 38.912  -25.156 36.009  1.00 39.16  ? 26  TYR D CG  1 
ATOM   4241 C  CD1 . TYR D 1 26  ? 37.625  -25.466 36.442  1.00 38.96  ? 26  TYR D CD1 1 
ATOM   4242 C  CD2 . TYR D 1 26  ? 39.088  -24.062 35.154  1.00 32.25  ? 26  TYR D CD2 1 
ATOM   4243 C  CE1 . TYR D 1 26  ? 36.552  -24.699 36.055  1.00 40.59  ? 26  TYR D CE1 1 
ATOM   4244 C  CE2 . TYR D 1 26  ? 38.030  -23.287 34.770  1.00 32.49  ? 26  TYR D CE2 1 
ATOM   4245 C  CZ  . TYR D 1 26  ? 36.758  -23.615 35.214  1.00 36.70  ? 26  TYR D CZ  1 
ATOM   4246 O  OH  . TYR D 1 26  ? 35.682  -22.871 34.826  1.00 35.48  ? 26  TYR D OH  1 
ATOM   4247 N  N   . ALA D 1 27  ? 40.868  -26.719 33.587  1.00 31.11  ? 27  ALA D N   1 
ATOM   4248 C  CA  . ALA D 1 27  ? 40.809  -26.594 32.126  1.00 33.70  ? 27  ALA D CA  1 
ATOM   4249 C  C   . ALA D 1 27  ? 40.564  -27.949 31.457  1.00 35.06  ? 27  ALA D C   1 
ATOM   4250 O  O   . ALA D 1 27  ? 39.861  -28.035 30.441  1.00 31.40  ? 27  ALA D O   1 
ATOM   4251 C  CB  . ALA D 1 27  ? 42.091  -25.956 31.579  1.00 31.76  ? 27  ALA D CB  1 
ATOM   4252 N  N   . SER D 1 28  ? 41.107  -29.029 32.022  1.00 30.67  ? 28  SER D N   1 
ATOM   4253 C  CA  . SER D 1 28  ? 40.851  -30.335 31.423  1.00 34.87  ? 28  SER D CA  1 
ATOM   4254 C  C   . SER D 1 28  ? 39.367  -30.671 31.512  1.00 33.06  ? 28  SER D C   1 
ATOM   4255 O  O   . SER D 1 28  ? 38.754  -31.091 30.522  1.00 33.49  ? 28  SER D O   1 
ATOM   4256 C  CB  . SER D 1 28  ? 41.713  -31.412 32.086  1.00 29.86  ? 28  SER D CB  1 
ATOM   4257 O  OG  . SER D 1 28  ? 41.310  -32.712 31.687  1.00 31.93  ? 28  SER D OG  1 
ATOM   4258 N  N   . TYR D 1 29  ? 38.760  -30.426 32.680  1.00 33.08  ? 29  TYR D N   1 
ATOM   4259 C  CA  . TYR D 1 29  ? 37.317  -30.620 32.841  1.00 30.30  ? 29  TYR D CA  1 
ATOM   4260 C  C   . TYR D 1 29  ? 36.520  -29.746 31.872  1.00 32.05  ? 29  TYR D C   1 
ATOM   4261 O  O   . TYR D 1 29  ? 35.541  -30.211 31.282  1.00 30.98  ? 29  TYR D O   1 
ATOM   4262 C  CB  . TYR D 1 29  ? 36.907  -30.298 34.278  1.00 31.04  ? 29  TYR D CB  1 
ATOM   4263 C  CG  . TYR D 1 29  ? 35.680  -31.017 34.796  1.00 32.21  ? 29  TYR D CG  1 
ATOM   4264 C  CD1 . TYR D 1 29  ? 35.188  -32.152 34.168  1.00 31.99  ? 29  TYR D CD1 1 
ATOM   4265 C  CD2 . TYR D 1 29  ? 35.045  -30.580 35.955  1.00 33.64  ? 29  TYR D CD2 1 
ATOM   4266 C  CE1 . TYR D 1 29  ? 34.083  -32.828 34.671  1.00 30.86  ? 29  TYR D CE1 1 
ATOM   4267 C  CE2 . TYR D 1 29  ? 33.944  -31.233 36.460  1.00 30.69  ? 29  TYR D CE2 1 
ATOM   4268 C  CZ  . TYR D 1 29  ? 33.467  -32.358 35.816  1.00 33.43  ? 29  TYR D CZ  1 
ATOM   4269 O  OH  . TYR D 1 29  ? 32.379  -33.003 36.327  1.00 27.12  ? 29  TYR D OH  1 
ATOM   4270 N  N   . VAL D 1 30  ? 36.887  -28.463 31.737  1.00 26.80  ? 30  VAL D N   1 
ATOM   4271 C  CA  . VAL D 1 30  ? 36.181  -27.604 30.797  1.00 30.61  ? 30  VAL D CA  1 
ATOM   4272 C  C   . VAL D 1 30  ? 36.163  -28.258 29.416  1.00 35.68  ? 30  VAL D C   1 
ATOM   4273 O  O   . VAL D 1 30  ? 35.097  -28.459 28.820  1.00 31.32  ? 30  VAL D O   1 
ATOM   4274 C  CB  . VAL D 1 30  ? 36.819  -26.199 30.751  1.00 33.56  ? 30  VAL D CB  1 
ATOM   4275 C  CG1 . VAL D 1 30  ? 36.208  -25.367 29.618  1.00 30.09  ? 30  VAL D CG1 1 
ATOM   4276 C  CG2 . VAL D 1 30  ? 36.661  -25.462 32.083  1.00 27.31  ? 30  VAL D CG2 1 
ATOM   4277 N  N   . TYR D 1 31  ? 37.345  -28.649 28.911  1.00 30.72  ? 31  TYR D N   1 
ATOM   4278 C  CA  . TYR D 1 31  ? 37.420  -29.235 27.577  1.00 35.81  ? 31  TYR D CA  1 
ATOM   4279 C  C   . TYR D 1 31  ? 36.609  -30.524 27.482  1.00 34.65  ? 31  TYR D C   1 
ATOM   4280 O  O   . TYR D 1 31  ? 36.032  -30.811 26.428  1.00 34.25  ? 31  TYR D O   1 
ATOM   4281 C  CB  . TYR D 1 31  ? 38.875  -29.492 27.186  1.00 33.38  ? 31  TYR D CB  1 
ATOM   4282 C  CG  . TYR D 1 31  ? 39.636  -28.257 26.803  1.00 35.66  ? 31  TYR D CG  1 
ATOM   4283 C  CD1 . TYR D 1 31  ? 39.087  -27.327 25.934  1.00 40.40  ? 31  TYR D CD1 1 
ATOM   4284 C  CD2 . TYR D 1 31  ? 40.901  -28.002 27.328  1.00 38.77  ? 31  TYR D CD2 1 
ATOM   4285 C  CE1 . TYR D 1 31  ? 39.773  -26.190 25.581  1.00 39.29  ? 31  TYR D CE1 1 
ATOM   4286 C  CE2 . TYR D 1 31  ? 41.597  -26.858 26.987  1.00 40.27  ? 31  TYR D CE2 1 
ATOM   4287 C  CZ  . TYR D 1 31  ? 41.029  -25.953 26.107  1.00 42.56  ? 31  TYR D CZ  1 
ATOM   4288 O  OH  . TYR D 1 31  ? 41.714  -24.803 25.739  1.00 48.24  ? 31  TYR D OH  1 
ATOM   4289 N  N   . LEU D 1 32  ? 36.550  -31.308 28.563  1.00 34.68  ? 32  LEU D N   1 
ATOM   4290 C  CA  . LEU D 1 32  ? 35.735  -32.521 28.558  1.00 35.16  ? 32  LEU D CA  1 
ATOM   4291 C  C   . LEU D 1 32  ? 34.254  -32.171 28.404  1.00 43.15  ? 32  LEU D C   1 
ATOM   4292 O  O   . LEU D 1 32  ? 33.507  -32.835 27.655  1.00 32.29  ? 32  LEU D O   1 
ATOM   4293 C  CB  . LEU D 1 32  ? 35.994  -33.324 29.841  1.00 31.86  ? 32  LEU D CB  1 
ATOM   4294 C  CG  . LEU D 1 32  ? 35.408  -34.752 29.952  1.00 42.32  ? 32  LEU D CG  1 
ATOM   4295 C  CD1 . LEU D 1 32  ? 36.025  -35.724 28.951  1.00 39.59  ? 32  LEU D CD1 1 
ATOM   4296 C  CD2 . LEU D 1 32  ? 35.520  -35.323 31.380  1.00 28.82  ? 32  LEU D CD2 1 
ATOM   4297 N  N   . SER D 1 33  ? 33.827  -31.093 29.074  1.00 35.49  ? 33  SER D N   1 
ATOM   4298 C  CA  . SER D 1 33  ? 32.473  -30.583 28.907  1.00 31.58  ? 33  SER D CA  1 
ATOM   4299 C  C   . SER D 1 33  ? 32.190  -30.238 27.447  1.00 32.91  ? 33  SER D C   1 
ATOM   4300 O  O   . SER D 1 33  ? 31.171  -30.656 26.880  1.00 33.17  ? 33  SER D O   1 
ATOM   4301 C  CB  . SER D 1 33  ? 32.293  -29.364 29.802  1.00 31.76  ? 33  SER D CB  1 
ATOM   4302 O  OG  . SER D 1 33  ? 31.203  -28.585 29.377  1.00 30.59  ? 33  SER D OG  1 
ATOM   4303 N  N   . MET D 1 34  ? 33.097  -29.481 26.819  1.00 31.14  ? 34  MET D N   1 
ATOM   4304 C  CA  . MET D 1 34  ? 32.911  -29.090 25.426  1.00 36.60  ? 34  MET D CA  1 
ATOM   4305 C  C   . MET D 1 34  ? 32.919  -30.301 24.499  1.00 36.22  ? 34  MET D C   1 
ATOM   4306 O  O   . MET D 1 34  ? 32.107  -30.378 23.574  1.00 35.15  ? 34  MET D O   1 
ATOM   4307 C  CB  . MET D 1 34  ? 33.989  -28.096 25.003  1.00 34.21  ? 34  MET D CB  1 
ATOM   4308 C  CG  . MET D 1 34  ? 33.973  -26.783 25.767  1.00 34.93  ? 34  MET D CG  1 
ATOM   4309 S  SD  . MET D 1 34  ? 35.356  -25.750 25.222  1.00 39.71  ? 34  MET D SD  1 
ATOM   4310 C  CE  . MET D 1 34  ? 35.133  -24.299 26.255  1.00 35.57  ? 34  MET D CE  1 
ATOM   4311 N  N   . ALA D 1 35  ? 33.819  -31.261 24.738  1.00 33.17  ? 35  ALA D N   1 
ATOM   4312 C  CA  . ALA D 1 35  ? 33.921  -32.418 23.855  1.00 35.95  ? 35  ALA D CA  1 
ATOM   4313 C  C   . ALA D 1 35  ? 32.586  -33.136 23.737  1.00 35.74  ? 35  ALA D C   1 
ATOM   4314 O  O   . ALA D 1 35  ? 32.103  -33.386 22.629  1.00 40.52  ? 35  ALA D O   1 
ATOM   4315 C  CB  . ALA D 1 35  ? 34.999  -33.383 24.351  1.00 34.13  ? 35  ALA D CB  1 
ATOM   4316 N  N   . TYR D 1 36  ? 31.968  -33.467 24.872  1.00 39.68  ? 36  TYR D N   1 
ATOM   4317 C  CA  . TYR D 1 36  ? 30.708  -34.205 24.842  1.00 37.20  ? 36  TYR D CA  1 
ATOM   4318 C  C   . TYR D 1 36  ? 29.501  -33.312 24.548  1.00 33.53  ? 36  TYR D C   1 
ATOM   4319 O  O   . TYR D 1 36  ? 28.464  -33.826 24.122  1.00 33.22  ? 36  TYR D O   1 
ATOM   4320 C  CB  . TYR D 1 36  ? 30.556  -35.013 26.150  1.00 28.56  ? 36  TYR D CB  1 
ATOM   4321 C  CG  . TYR D 1 36  ? 31.506  -36.191 26.110  1.00 38.53  ? 36  TYR D CG  1 
ATOM   4322 C  CD1 . TYR D 1 36  ? 32.812  -36.062 26.527  1.00 32.65  ? 36  TYR D CD1 1 
ATOM   4323 C  CD2 . TYR D 1 36  ? 31.123  -37.402 25.526  1.00 40.96  ? 36  TYR D CD2 1 
ATOM   4324 C  CE1 . TYR D 1 36  ? 33.698  -37.122 26.434  1.00 43.15  ? 36  TYR D CE1 1 
ATOM   4325 C  CE2 . TYR D 1 36  ? 32.007  -38.468 25.419  1.00 38.32  ? 36  TYR D CE2 1 
ATOM   4326 C  CZ  . TYR D 1 36  ? 33.296  -38.322 25.873  1.00 44.33  ? 36  TYR D CZ  1 
ATOM   4327 O  OH  . TYR D 1 36  ? 34.195  -39.373 25.784  1.00 44.69  ? 36  TYR D OH  1 
ATOM   4328 N  N   . TYR D 1 37  ? 29.615  -31.989 24.715  1.00 30.47  ? 37  TYR D N   1 
ATOM   4329 C  CA  . TYR D 1 37  ? 28.565  -31.115 24.197  1.00 34.84  ? 37  TYR D CA  1 
ATOM   4330 C  C   . TYR D 1 37  ? 28.477  -31.225 22.677  1.00 41.40  ? 37  TYR D C   1 
ATOM   4331 O  O   . TYR D 1 37  ? 27.380  -31.253 22.099  1.00 37.54  ? 37  TYR D O   1 
ATOM   4332 C  CB  . TYR D 1 37  ? 28.828  -29.661 24.611  1.00 37.50  ? 37  TYR D CB  1 
ATOM   4333 C  CG  . TYR D 1 37  ? 27.870  -28.633 24.009  1.00 38.95  ? 37  TYR D CG  1 
ATOM   4334 C  CD1 . TYR D 1 37  ? 26.661  -28.322 24.624  1.00 40.36  ? 37  TYR D CD1 1 
ATOM   4335 C  CD2 . TYR D 1 37  ? 28.183  -27.973 22.823  1.00 43.82  ? 37  TYR D CD2 1 
ATOM   4336 C  CE1 . TYR D 1 37  ? 25.785  -27.379 24.072  1.00 40.88  ? 37  TYR D CE1 1 
ATOM   4337 C  CE2 . TYR D 1 37  ? 27.316  -27.031 22.263  1.00 40.79  ? 37  TYR D CE2 1 
ATOM   4338 C  CZ  . TYR D 1 37  ? 26.123  -26.742 22.893  1.00 46.51  ? 37  TYR D CZ  1 
ATOM   4339 O  OH  . TYR D 1 37  ? 25.282  -25.807 22.329  1.00 49.97  ? 37  TYR D OH  1 
ATOM   4340 N  N   . PHE D 1 38  ? 29.622  -31.291 22.006  1.00 35.33  ? 38  PHE D N   1 
ATOM   4341 C  CA  . PHE D 1 38  ? 29.577  -31.335 20.558  1.00 38.53  ? 38  PHE D CA  1 
ATOM   4342 C  C   . PHE D 1 38  ? 29.233  -32.720 20.027  1.00 39.53  ? 38  PHE D C   1 
ATOM   4343 O  O   . PHE D 1 38  ? 29.173  -32.904 18.810  1.00 37.68  ? 38  PHE D O   1 
ATOM   4344 C  CB  . PHE D 1 38  ? 30.889  -30.793 20.002  1.00 36.22  ? 38  PHE D CB  1 
ATOM   4345 C  CG  . PHE D 1 38  ? 30.969  -29.293 20.093  1.00 38.60  ? 38  PHE D CG  1 
ATOM   4346 C  CD1 . PHE D 1 38  ? 30.192  -28.501 19.269  1.00 39.14  ? 38  PHE D CD1 1 
ATOM   4347 C  CD2 . PHE D 1 38  ? 31.774  -28.675 21.037  1.00 41.48  ? 38  PHE D CD2 1 
ATOM   4348 C  CE1 . PHE D 1 38  ? 30.235  -27.125 19.359  1.00 42.56  ? 38  PHE D CE1 1 
ATOM   4349 C  CE2 . PHE D 1 38  ? 31.818  -27.287 21.146  1.00 36.36  ? 38  PHE D CE2 1 
ATOM   4350 C  CZ  . PHE D 1 38  ? 31.051  -26.514 20.303  1.00 42.60  ? 38  PHE D CZ  1 
ATOM   4351 N  N   . GLU D 1 39  ? 28.946  -33.671 20.910  1.00 37.28  ? 39  GLU D N   1 
ATOM   4352 C  CA  . GLU D 1 39  ? 28.405  -34.963 20.523  1.00 37.51  ? 39  GLU D CA  1 
ATOM   4353 C  C   . GLU D 1 39  ? 26.918  -35.101 20.827  1.00 39.88  ? 39  GLU D C   1 
ATOM   4354 O  O   . GLU D 1 39  ? 26.366  -36.192 20.664  1.00 43.07  ? 39  GLU D O   1 
ATOM   4355 C  CB  . GLU D 1 39  ? 29.176  -36.082 21.226  1.00 38.83  ? 39  GLU D CB  1 
ATOM   4356 C  CG  . GLU D 1 39  ? 30.629  -36.177 20.813  1.00 31.34  ? 39  GLU D CG  1 
ATOM   4357 C  CD  . GLU D 1 39  ? 31.276  -37.455 21.320  1.00 42.96  ? 39  GLU D CD  1 
ATOM   4358 O  OE1 . GLU D 1 39  ? 30.591  -38.249 22.016  1.00 42.66  ? 39  GLU D OE1 1 
ATOM   4359 O  OE2 . GLU D 1 39  ? 32.469  -37.672 21.012  1.00 55.53  ? 39  GLU D OE2 1 
ATOM   4360 N  N   . ARG D 1 40  ? 26.254  -34.045 21.286  1.00 42.23  ? 40  ARG D N   1 
ATOM   4361 C  CA  . ARG D 1 40  ? 24.813  -34.144 21.464  1.00 44.36  ? 40  ARG D CA  1 
ATOM   4362 C  C   . ARG D 1 40  ? 24.131  -34.264 20.108  1.00 46.01  ? 40  ARG D C   1 
ATOM   4363 O  O   . ARG D 1 40  ? 24.601  -33.724 19.100  1.00 41.51  ? 40  ARG D O   1 
ATOM   4364 C  CB  . ARG D 1 40  ? 24.278  -32.943 22.238  1.00 45.10  ? 40  ARG D CB  1 
ATOM   4365 C  CG  . ARG D 1 40  ? 25.085  -32.668 23.492  1.00 41.41  ? 40  ARG D CG  1 
ATOM   4366 C  CD  . ARG D 1 40  ? 24.311  -31.905 24.524  1.00 48.75  ? 40  ARG D CD  1 
ATOM   4367 N  NE  . ARG D 1 40  ? 23.485  -30.855 23.948  1.00 53.65  ? 40  ARG D NE  1 
ATOM   4368 C  CZ  . ARG D 1 40  ? 23.183  -29.711 24.569  1.00 64.31  ? 40  ARG D CZ  1 
ATOM   4369 N  NH1 . ARG D 1 40  ? 23.656  -29.465 25.797  1.00 53.06  ? 40  ARG D NH1 1 
ATOM   4370 N  NH2 . ARG D 1 40  ? 22.405  -28.807 23.960  1.00 60.09  ? 40  ARG D NH2 1 
ATOM   4371 N  N   . ASP D 1 41  ? 23.022  -35.005 20.090  1.00 48.31  ? 41  ASP D N   1 
ATOM   4372 C  CA  . ASP D 1 41  ? 22.313  -35.266 18.843  1.00 46.18  ? 41  ASP D CA  1 
ATOM   4373 C  C   . ASP D 1 41  ? 21.775  -33.986 18.205  1.00 46.28  ? 41  ASP D C   1 
ATOM   4374 O  O   . ASP D 1 41  ? 21.573  -33.952 16.988  1.00 53.22  ? 41  ASP D O   1 
ATOM   4375 C  CB  . ASP D 1 41  ? 21.178  -36.259 19.085  1.00 54.19  ? 41  ASP D CB  1 
ATOM   4376 C  CG  . ASP D 1 41  ? 20.042  -35.653 19.881  1.00 62.28  ? 41  ASP D CG  1 
ATOM   4377 O  OD1 . ASP D 1 41  ? 20.138  -35.574 21.133  1.00 63.30  ? 41  ASP D OD1 1 
ATOM   4378 O  OD2 . ASP D 1 41  ? 19.060  -35.224 19.241  1.00 68.21  ? 41  ASP D OD2 1 
ATOM   4379 N  N   . ASP D 1 42  ? 21.551  -32.935 18.983  1.00 42.48  ? 42  ASP D N   1 
ATOM   4380 C  CA  . ASP D 1 42  ? 21.182  -31.637 18.435  1.00 42.24  ? 42  ASP D CA  1 
ATOM   4381 C  C   . ASP D 1 42  ? 22.398  -30.768 18.094  1.00 39.68  ? 42  ASP D C   1 
ATOM   4382 O  O   . ASP D 1 42  ? 22.231  -29.574 17.826  1.00 39.46  ? 42  ASP D O   1 
ATOM   4383 C  CB  . ASP D 1 42  ? 20.256  -30.890 19.407  1.00 41.59  ? 42  ASP D CB  1 
ATOM   4384 C  CG  . ASP D 1 42  ? 20.915  -30.608 20.762  1.00 48.25  ? 42  ASP D CG  1 
ATOM   4385 O  OD1 . ASP D 1 42  ? 21.886  -31.306 21.110  1.00 47.73  ? 42  ASP D OD1 1 
ATOM   4386 O  OD2 . ASP D 1 42  ? 20.449  -29.707 21.498  1.00 54.23  ? 42  ASP D OD2 1 
ATOM   4387 N  N   . VAL D 1 43  ? 23.607  -31.329 18.086  1.00 34.70  ? 43  VAL D N   1 
ATOM   4388 C  CA  . VAL D 1 43  ? 24.785  -30.531 17.760  1.00 42.11  ? 43  VAL D CA  1 
ATOM   4389 C  C   . VAL D 1 43  ? 25.589  -31.232 16.670  1.00 38.45  ? 43  VAL D C   1 
ATOM   4390 O  O   . VAL D 1 43  ? 25.690  -30.725 15.552  1.00 41.77  ? 43  VAL D O   1 
ATOM   4391 C  CB  . VAL D 1 43  ? 25.639  -30.233 19.012  1.00 42.53  ? 43  VAL D CB  1 
ATOM   4392 C  CG1 . VAL D 1 43  ? 26.897  -29.425 18.637  1.00 36.49  ? 43  VAL D CG1 1 
ATOM   4393 C  CG2 . VAL D 1 43  ? 24.831  -29.446 20.004  1.00 32.92  ? 43  VAL D CG2 1 
ATOM   4394 N  N   . CYS D 1 44  ? 26.168  -32.391 16.975  1.00 44.12  ? 44  CYS D N   1 
ATOM   4395 C  CA  . CYS D 1 44  ? 26.754  -33.280 15.959  1.00 45.75  ? 44  CYS D CA  1 
ATOM   4396 C  C   . CYS D 1 44  ? 27.879  -32.587 15.184  1.00 40.12  ? 44  CYS D C   1 
ATOM   4397 O  O   . CYS D 1 44  ? 27.852  -32.468 13.957  1.00 40.75  ? 44  CYS D O   1 
ATOM   4398 C  CB  . CYS D 1 44  ? 25.681  -33.810 14.991  1.00 42.07  ? 44  CYS D CB  1 
ATOM   4399 S  SG  . CYS D 1 44  ? 24.227  -34.596 15.765  1.00 60.53  ? 44  CYS D SG  1 
ATOM   4400 N  N   . LEU D 1 45  ? 28.896  -32.149 15.919  1.00 38.84  ? 45  LEU D N   1 
ATOM   4401 C  CA  . LEU D 1 45  ? 30.079  -31.530 15.330  1.00 39.23  ? 45  LEU D CA  1 
ATOM   4402 C  C   . LEU D 1 45  ? 31.262  -32.387 15.725  1.00 40.65  ? 45  LEU D C   1 
ATOM   4403 O  O   . LEU D 1 45  ? 32.068  -32.018 16.616  1.00 39.00  ? 45  LEU D O   1 
ATOM   4404 C  CB  . LEU D 1 45  ? 30.177  -30.066 15.757  1.00 34.66  ? 45  LEU D CB  1 
ATOM   4405 C  CG  . LEU D 1 45  ? 29.144  -29.197 15.039  1.00 36.62  ? 45  LEU D CG  1 
ATOM   4406 C  CD1 . LEU D 1 45  ? 29.156  -27.730 15.510  1.00 37.93  ? 45  LEU D CD1 1 
ATOM   4407 C  CD2 . LEU D 1 45  ? 29.374  -29.268 13.540  1.00 34.65  ? 45  LEU D CD2 1 
ATOM   4408 N  N   . PRO D 1 46  ? 31.438  -33.561 15.104  1.00 43.65  ? 46  PRO D N   1 
ATOM   4409 C  CA  . PRO D 1 46  ? 32.434  -34.524 15.586  1.00 41.46  ? 46  PRO D CA  1 
ATOM   4410 C  C   . PRO D 1 46  ? 33.859  -34.013 15.513  1.00 38.05  ? 46  PRO D C   1 
ATOM   4411 O  O   . PRO D 1 46  ? 34.666  -34.371 16.379  1.00 36.84  ? 46  PRO D O   1 
ATOM   4412 C  CB  . PRO D 1 46  ? 32.219  -35.752 14.686  1.00 37.30  ? 46  PRO D CB  1 
ATOM   4413 C  CG  . PRO D 1 46  ? 31.589  -35.201 13.425  1.00 36.24  ? 46  PRO D CG  1 
ATOM   4414 C  CD  . PRO D 1 46  ? 30.720  -34.056 13.897  1.00 39.01  ? 46  PRO D CD  1 
ATOM   4415 N  N   . GLY D 1 47  ? 34.199  -33.208 14.497  1.00 37.04  ? 47  GLY D N   1 
ATOM   4416 C  CA  . GLY D 1 47  ? 35.505  -32.565 14.478  1.00 41.76  ? 47  GLY D CA  1 
ATOM   4417 C  C   . GLY D 1 47  ? 35.733  -31.657 15.678  1.00 44.85  ? 47  GLY D C   1 
ATOM   4418 O  O   . GLY D 1 47  ? 36.802  -31.686 16.299  1.00 41.47  ? 47  GLY D O   1 
ATOM   4419 N  N   . PHE D 1 48  ? 34.729  -30.837 16.029  1.00 41.72  ? 48  PHE D N   1 
ATOM   4420 C  CA  . PHE D 1 48  ? 34.827  -30.055 17.263  1.00 40.29  ? 48  PHE D CA  1 
ATOM   4421 C  C   . PHE D 1 48  ? 34.998  -30.967 18.470  1.00 39.11  ? 48  PHE D C   1 
ATOM   4422 O  O   . PHE D 1 48  ? 35.819  -30.695 19.354  1.00 36.32  ? 48  PHE D O   1 
ATOM   4423 C  CB  . PHE D 1 48  ? 33.594  -29.184 17.450  1.00 39.74  ? 48  PHE D CB  1 
ATOM   4424 C  CG  . PHE D 1 48  ? 33.615  -27.890 16.670  1.00 39.46  ? 48  PHE D CG  1 
ATOM   4425 C  CD1 . PHE D 1 48  ? 34.186  -26.753 17.205  1.00 39.77  ? 48  PHE D CD1 1 
ATOM   4426 C  CD2 . PHE D 1 48  ? 33.009  -27.808 15.428  1.00 37.30  ? 48  PHE D CD2 1 
ATOM   4427 C  CE1 . PHE D 1 48  ? 34.157  -25.558 16.510  1.00 45.33  ? 48  PHE D CE1 1 
ATOM   4428 C  CE2 . PHE D 1 48  ? 32.994  -26.627 14.718  1.00 39.55  ? 48  PHE D CE2 1 
ATOM   4429 C  CZ  . PHE D 1 48  ? 33.562  -25.500 15.258  1.00 44.13  ? 48  PHE D CZ  1 
ATOM   4430 N  N   . ALA D 1 49  ? 34.253  -32.074 18.499  1.00 38.66  ? 49  ALA D N   1 
ATOM   4431 C  CA  . ALA D 1 49  ? 34.297  -32.977 19.642  1.00 41.37  ? 49  ALA D CA  1 
ATOM   4432 C  C   . ALA D 1 49  ? 35.680  -33.582 19.814  1.00 38.99  ? 49  ALA D C   1 
ATOM   4433 O  O   . ALA D 1 49  ? 36.207  -33.635 20.937  1.00 38.85  ? 49  ALA D O   1 
ATOM   4434 C  CB  . ALA D 1 49  ? 33.245  -34.075 19.470  1.00 38.48  ? 49  ALA D CB  1 
ATOM   4435 N  N   . LYS D 1 50  ? 36.284  -34.036 18.705  1.00 39.65  ? 50  LYS D N   1 
ATOM   4436 C  CA  . LYS D 1 50  ? 37.622  -34.630 18.736  1.00 41.37  ? 50  LYS D CA  1 
ATOM   4437 C  C   . LYS D 1 50  ? 38.656  -33.631 19.234  1.00 40.15  ? 50  LYS D C   1 
ATOM   4438 O  O   . LYS D 1 50  ? 39.481  -33.954 20.103  1.00 36.53  ? 50  LYS D O   1 
ATOM   4439 C  CB  . LYS D 1 50  ? 37.995  -35.130 17.338  1.00 43.68  ? 50  LYS D CB  1 
ATOM   4440 C  CG  . LYS D 1 50  ? 39.245  -35.963 17.265  1.00 42.27  ? 50  LYS D CG  1 
ATOM   4441 C  CD  . LYS D 1 50  ? 39.439  -36.488 15.848  1.00 51.96  ? 50  LYS D CD  1 
ATOM   4442 C  CE  . LYS D 1 50  ? 40.640  -37.426 15.757  1.00 62.84  ? 50  LYS D CE  1 
ATOM   4443 N  NZ  . LYS D 1 50  ? 41.941  -36.704 15.571  1.00 60.88  ? 50  LYS D NZ  1 
ATOM   4444 N  N   . PHE D 1 51  ? 38.603  -32.396 18.722  1.00 32.90  ? 51  PHE D N   1 
ATOM   4445 C  CA  . PHE D 1 51  ? 39.603  -31.403 19.097  1.00 35.47  ? 51  PHE D CA  1 
ATOM   4446 C  C   . PHE D 1 51  ? 39.602  -31.146 20.600  1.00 42.83  ? 51  PHE D C   1 
ATOM   4447 O  O   . PHE D 1 51  ? 40.672  -31.081 21.221  1.00 39.15  ? 51  PHE D O   1 
ATOM   4448 C  CB  . PHE D 1 51  ? 39.356  -30.110 18.334  1.00 36.02  ? 51  PHE D CB  1 
ATOM   4449 C  CG  . PHE D 1 51  ? 40.217  -28.964 18.783  1.00 38.38  ? 51  PHE D CG  1 
ATOM   4450 C  CD1 . PHE D 1 51  ? 41.515  -28.829 18.316  1.00 38.15  ? 51  PHE D CD1 1 
ATOM   4451 C  CD2 . PHE D 1 51  ? 39.717  -28.003 19.669  1.00 37.98  ? 51  PHE D CD2 1 
ATOM   4452 C  CE1 . PHE D 1 51  ? 42.319  -27.768 18.736  1.00 42.12  ? 51  PHE D CE1 1 
ATOM   4453 C  CE2 . PHE D 1 51  ? 40.511  -26.925 20.077  1.00 38.22  ? 51  PHE D CE2 1 
ATOM   4454 C  CZ  . PHE D 1 51  ? 41.814  -26.809 19.611  1.00 39.41  ? 51  PHE D CZ  1 
ATOM   4455 N  N   . PHE D 1 52  ? 38.407  -30.994 21.202  1.00 39.10  ? 52  PHE D N   1 
ATOM   4456 C  CA  . PHE D 1 52  ? 38.305  -30.704 22.629  1.00 37.88  ? 52  PHE D CA  1 
ATOM   4457 C  C   . PHE D 1 52  ? 38.625  -31.931 23.479  1.00 37.17  ? 52  PHE D C   1 
ATOM   4458 O  O   . PHE D 1 52  ? 39.218  -31.794 24.552  1.00 37.07  ? 52  PHE D O   1 
ATOM   4459 C  CB  . PHE D 1 52  ? 36.907  -30.163 22.961  1.00 34.48  ? 52  PHE D CB  1 
ATOM   4460 C  CG  . PHE D 1 52  ? 36.630  -28.787 22.387  1.00 39.93  ? 52  PHE D CG  1 
ATOM   4461 C  CD1 . PHE D 1 52  ? 37.502  -27.721 22.624  1.00 37.05  ? 52  PHE D CD1 1 
ATOM   4462 C  CD2 . PHE D 1 52  ? 35.492  -28.552 21.616  1.00 36.81  ? 52  PHE D CD2 1 
ATOM   4463 C  CE1 . PHE D 1 52  ? 37.244  -26.448 22.095  1.00 37.18  ? 52  PHE D CE1 1 
ATOM   4464 C  CE2 . PHE D 1 52  ? 35.234  -27.273 21.071  1.00 35.00  ? 52  PHE D CE2 1 
ATOM   4465 C  CZ  . PHE D 1 52  ? 36.115  -26.228 21.310  1.00 31.85  ? 52  PHE D CZ  1 
ATOM   4466 N  N   . LYS D 1 53  ? 38.262  -33.132 23.018  1.00 39.99  ? 53  LYS D N   1 
ATOM   4467 C  CA  . LYS D 1 53  ? 38.651  -34.339 23.750  1.00 42.52  ? 53  LYS D CA  1 
ATOM   4468 C  C   . LYS D 1 53  ? 40.164  -34.448 23.854  1.00 42.68  ? 53  LYS D C   1 
ATOM   4469 O  O   . LYS D 1 53  ? 40.688  -34.843 24.905  1.00 43.00  ? 53  LYS D O   1 
ATOM   4470 C  CB  . LYS D 1 53  ? 38.075  -35.593 23.082  1.00 38.72  ? 53  LYS D CB  1 
ATOM   4471 C  CG  . LYS D 1 53  ? 37.411  -36.538 24.081  1.00 56.70  ? 53  LYS D CG  1 
ATOM   4472 C  CD  . LYS D 1 53  ? 36.766  -37.783 23.439  1.00 63.87  ? 53  LYS D CD  1 
ATOM   4473 C  CE  . LYS D 1 53  ? 35.651  -37.465 22.433  1.00 53.42  ? 53  LYS D CE  1 
ATOM   4474 N  NZ  . LYS D 1 53  ? 34.964  -38.726 22.014  1.00 46.95  ? 53  LYS D NZ  1 
ATOM   4475 N  N   . GLU D 1 54  ? 40.879  -34.058 22.794  1.00 38.32  ? 54  GLU D N   1 
ATOM   4476 C  CA  . GLU D 1 54  ? 42.341  -34.104 22.818  1.00 43.64  ? 54  GLU D CA  1 
ATOM   4477 C  C   . GLU D 1 54  ? 42.918  -33.012 23.707  1.00 43.00  ? 54  GLU D C   1 
ATOM   4478 O  O   . GLU D 1 54  ? 43.869  -33.257 24.464  1.00 40.21  ? 54  GLU D O   1 
ATOM   4479 C  CB  . GLU D 1 54  ? 42.896  -33.969 21.405  1.00 36.78  ? 54  GLU D CB  1 
ATOM   4480 C  CG  . GLU D 1 54  ? 42.461  -35.055 20.459  1.00 44.94  ? 54  GLU D CG  1 
ATOM   4481 C  CD  . GLU D 1 54  ? 42.926  -34.789 19.037  1.00 54.99  ? 54  GLU D CD  1 
ATOM   4482 O  OE1 . GLU D 1 54  ? 43.158  -33.601 18.698  1.00 56.80  ? 54  GLU D OE1 1 
ATOM   4483 O  OE2 . GLU D 1 54  ? 43.077  -35.768 18.273  1.00 56.78  ? 54  GLU D OE2 1 
ATOM   4484 N  N   . SER D 1 55  ? 42.372  -31.795 23.606  1.00 36.21  ? 55  SER D N   1 
ATOM   4485 C  CA  . SER D 1 55  ? 42.767  -30.729 24.513  1.00 35.46  ? 55  SER D CA  1 
ATOM   4486 C  C   . SER D 1 55  ? 42.502  -31.117 25.976  1.00 41.22  ? 55  SER D C   1 
ATOM   4487 O  O   . SER D 1 55  ? 43.324  -30.831 26.861  1.00 33.91  ? 55  SER D O   1 
ATOM   4488 C  CB  . SER D 1 55  ? 42.029  -29.451 24.130  1.00 38.39  ? 55  SER D CB  1 
ATOM   4489 O  OG  . SER D 1 55  ? 42.551  -28.926 22.917  1.00 44.20  ? 55  SER D OG  1 
ATOM   4490 N  N   . SER D 1 56  ? 41.381  -31.799 26.248  1.00 33.22  ? 56  SER D N   1 
ATOM   4491 C  CA  . SER D 1 56  ? 41.133  -32.299 27.601  1.00 39.53  ? 56  SER D CA  1 
ATOM   4492 C  C   . SER D 1 56  ? 42.243  -33.237 28.080  1.00 36.84  ? 56  SER D C   1 
ATOM   4493 O  O   . SER D 1 56  ? 42.794  -33.046 29.169  1.00 36.76  ? 56  SER D O   1 
ATOM   4494 C  CB  . SER D 1 56  ? 39.788  -33.008 27.682  1.00 36.58  ? 56  SER D CB  1 
ATOM   4495 O  OG  . SER D 1 56  ? 39.523  -33.317 29.035  1.00 31.35  ? 56  SER D OG  1 
ATOM   4496 N  N   . ASP D 1 57  ? 42.556  -34.279 27.301  1.00 36.27  ? 57  ASP D N   1 
ATOM   4497 C  CA  . ASP D 1 57  ? 43.667  -35.163 27.653  1.00 40.89  ? 57  ASP D CA  1 
ATOM   4498 C  C   . ASP D 1 57  ? 44.958  -34.376 27.822  1.00 43.28  ? 57  ASP D C   1 
ATOM   4499 O  O   . ASP D 1 57  ? 45.723  -34.611 28.765  1.00 41.71  ? 57  ASP D O   1 
ATOM   4500 C  CB  . ASP D 1 57  ? 43.871  -36.236 26.580  1.00 40.66  ? 57  ASP D CB  1 
ATOM   4501 C  CG  . ASP D 1 57  ? 42.657  -37.135 26.390  1.00 44.28  ? 57  ASP D CG  1 
ATOM   4502 O  OD1 . ASP D 1 57  ? 41.850  -37.280 27.325  1.00 48.26  ? 57  ASP D OD1 1 
ATOM   4503 O  OD2 . ASP D 1 57  ? 42.519  -37.712 25.291  1.00 42.56  ? 57  ASP D OD2 1 
ATOM   4504 N  N   . GLU D 1 58  ? 45.212  -33.443 26.904  1.00 41.64  ? 58  GLU D N   1 
ATOM   4505 C  CA  . GLU D 1 58  ? 46.422  -32.633 26.946  1.00 42.00  ? 58  GLU D CA  1 
ATOM   4506 C  C   . GLU D 1 58  ? 46.533  -31.884 28.269  1.00 45.00  ? 58  GLU D C   1 
ATOM   4507 O  O   . GLU D 1 58  ? 47.565  -31.953 28.947  1.00 46.52  ? 58  GLU D O   1 
ATOM   4508 C  CB  . GLU D 1 58  ? 46.416  -31.674 25.755  1.00 41.59  ? 58  GLU D CB  1 
ATOM   4509 C  CG  . GLU D 1 58  ? 47.739  -31.007 25.393  1.00 62.49  ? 58  GLU D CG  1 
ATOM   4510 C  CD  . GLU D 1 58  ? 47.750  -30.431 23.960  1.00 74.97  ? 58  GLU D CD  1 
ATOM   4511 O  OE1 . GLU D 1 58  ? 47.116  -31.034 23.054  1.00 66.59  ? 58  GLU D OE1 1 
ATOM   4512 O  OE2 . GLU D 1 58  ? 48.405  -29.379 23.744  1.00 81.38  ? 58  GLU D OE2 1 
ATOM   4513 N  N   . GLU D 1 59  ? 45.464  -31.182 28.666  1.00 40.72  ? 59  GLU D N   1 
ATOM   4514 C  CA  . GLU D 1 59  ? 45.476  -30.431 29.920  1.00 43.45  ? 59  GLU D CA  1 
ATOM   4515 C  C   . GLU D 1 59  ? 45.702  -31.344 31.118  1.00 41.44  ? 59  GLU D C   1 
ATOM   4516 O  O   . GLU D 1 59  ? 46.414  -30.985 32.067  1.00 42.15  ? 59  GLU D O   1 
ATOM   4517 C  CB  . GLU D 1 59  ? 44.164  -29.669 30.091  1.00 40.68  ? 59  GLU D CB  1 
ATOM   4518 C  CG  . GLU D 1 59  ? 43.986  -28.550 29.122  1.00 40.40  ? 59  GLU D CG  1 
ATOM   4519 C  CD  . GLU D 1 59  ? 45.143  -27.586 29.165  1.00 48.47  ? 59  GLU D CD  1 
ATOM   4520 O  OE1 . GLU D 1 59  ? 45.652  -27.318 30.269  1.00 55.80  ? 59  GLU D OE1 1 
ATOM   4521 O  OE2 . GLU D 1 59  ? 45.553  -27.101 28.096  1.00 62.06  ? 59  GLU D OE2 1 
ATOM   4522 N  N   . ARG D 1 60  ? 45.107  -32.529 31.089  1.00 34.44  ? 60  ARG D N   1 
ATOM   4523 C  CA  . ARG D 1 60  ? 45.319  -33.478 32.174  1.00 43.82  ? 60  ARG D CA  1 
ATOM   4524 C  C   . ARG D 1 60  ? 46.783  -33.894 32.277  1.00 44.27  ? 60  ARG D C   1 
ATOM   4525 O  O   . ARG D 1 60  ? 47.322  -33.996 33.382  1.00 40.91  ? 60  ARG D O   1 
ATOM   4526 C  CB  . ARG D 1 60  ? 44.431  -34.696 31.971  1.00 40.00  ? 60  ARG D CB  1 
ATOM   4527 C  CG  . ARG D 1 60  ? 44.525  -35.702 33.065  1.00 42.78  ? 60  ARG D CG  1 
ATOM   4528 C  CD  . ARG D 1 60  ? 43.267  -36.510 33.092  1.00 37.39  ? 60  ARG D CD  1 
ATOM   4529 N  NE  . ARG D 1 60  ? 43.364  -37.646 33.987  1.00 45.99  ? 60  ARG D NE  1 
ATOM   4530 C  CZ  . ARG D 1 60  ? 43.973  -38.792 33.686  1.00 60.18  ? 60  ARG D CZ  1 
ATOM   4531 N  NH1 . ARG D 1 60  ? 43.994  -39.801 34.579  1.00 46.84  ? 60  ARG D NH1 1 
ATOM   4532 N  NH2 . ARG D 1 60  ? 44.564  -38.927 32.495  1.00 56.11  ? 60  ARG D NH2 1 
ATOM   4533 N  N   . GLU D 1 61  ? 47.442  -34.143 31.138  1.00 44.68  ? 61  GLU D N   1 
ATOM   4534 C  CA  . GLU D 1 61  ? 48.853  -34.502 31.189  1.00 47.51  ? 61  GLU D CA  1 
ATOM   4535 C  C   . GLU D 1 61  ? 49.692  -33.338 31.682  1.00 45.06  ? 61  GLU D C   1 
ATOM   4536 O  O   . GLU D 1 61  ? 50.652  -33.550 32.427  1.00 47.08  ? 61  GLU D O   1 
ATOM   4537 C  CB  . GLU D 1 61  ? 49.359  -34.993 29.826  1.00 43.03  ? 61  GLU D CB  1 
ATOM   4538 C  CG  . GLU D 1 61  ? 48.478  -36.085 29.194  1.00 57.74  ? 61  GLU D CG  1 
ATOM   4539 C  CD  . GLU D 1 61  ? 48.555  -37.422 29.929  1.00 70.61  ? 61  GLU D CD  1 
ATOM   4540 O  OE1 . GLU D 1 61  ? 47.501  -37.911 30.434  1.00 69.99  ? 61  GLU D OE1 1 
ATOM   4541 O  OE2 . GLU D 1 61  ? 49.673  -37.983 29.995  1.00 72.36  ? 61  GLU D OE2 1 
ATOM   4542 N  N   . HIS D 1 62  ? 49.329  -32.106 31.323  1.00 45.06  ? 62  HIS D N   1 
ATOM   4543 C  CA  . HIS D 1 62  ? 50.054  -30.958 31.859  1.00 48.62  ? 62  HIS D CA  1 
ATOM   4544 C  C   . HIS D 1 62  ? 49.905  -30.875 33.377  1.00 46.90  ? 62  HIS D C   1 
ATOM   4545 O  O   . HIS D 1 62  ? 50.871  -30.575 34.088  1.00 43.23  ? 62  HIS D O   1 
ATOM   4546 C  CB  . HIS D 1 62  ? 49.581  -29.671 31.182  1.00 50.87  ? 62  HIS D CB  1 
ATOM   4547 C  CG  . HIS D 1 62  ? 49.899  -29.614 29.718  1.00 65.56  ? 62  HIS D CG  1 
ATOM   4548 N  ND1 . HIS D 1 62  ? 49.851  -28.446 28.987  1.00 67.90  ? 62  HIS D ND1 1 
ATOM   4549 C  CD2 . HIS D 1 62  ? 50.274  -30.585 28.848  1.00 68.24  ? 62  HIS D CD2 1 
ATOM   4550 C  CE1 . HIS D 1 62  ? 50.180  -28.699 27.732  1.00 71.16  ? 62  HIS D CE1 1 
ATOM   4551 N  NE2 . HIS D 1 62  ? 50.439  -29.991 27.620  1.00 66.26  ? 62  HIS D NE2 1 
ATOM   4552 N  N   . ALA D 1 63  ? 48.709  -31.166 33.896  1.00 41.37  ? 63  ALA D N   1 
ATOM   4553 C  CA  . ALA D 1 63  ? 48.544  -31.244 35.342  1.00 42.76  ? 63  ALA D CA  1 
ATOM   4554 C  C   . ALA D 1 63  ? 49.504  -32.262 35.944  1.00 44.46  ? 63  ALA D C   1 
ATOM   4555 O  O   . ALA D 1 63  ? 50.110  -32.019 36.996  1.00 38.39  ? 63  ALA D O   1 
ATOM   4556 C  CB  . ALA D 1 63  ? 47.094  -31.594 35.693  1.00 39.29  ? 63  ALA D CB  1 
ATOM   4557 N  N   . GLN D 1 64  ? 49.675  -33.403 35.273  1.00 43.72  ? 64  GLN D N   1 
ATOM   4558 C  CA  . GLN D 1 64  ? 50.536  -34.445 35.804  1.00 41.00  ? 64  GLN D CA  1 
ATOM   4559 C  C   . GLN D 1 64  ? 52.006  -34.061 35.714  1.00 44.17  ? 64  GLN D C   1 
ATOM   4560 O  O   . GLN D 1 64  ? 52.820  -34.562 36.492  1.00 43.59  ? 64  GLN D O   1 
ATOM   4561 C  CB  . GLN D 1 64  ? 50.257  -35.746 35.075  1.00 41.37  ? 64  GLN D CB  1 
ATOM   4562 C  CG  . GLN D 1 64  ? 48.925  -36.334 35.487  1.00 44.81  ? 64  GLN D CG  1 
ATOM   4563 C  CD  . GLN D 1 64  ? 48.583  -37.585 34.723  1.00 43.08  ? 64  GLN D CD  1 
ATOM   4564 O  OE1 . GLN D 1 64  ? 47.646  -37.604 33.935  1.00 48.11  ? 64  GLN D OE1 1 
ATOM   4565 N  NE2 . GLN D 1 64  ? 49.325  -38.649 34.973  1.00 48.66  ? 64  GLN D NE2 1 
ATOM   4566 N  N   . THR D 1 65  ? 52.361  -33.170 34.790  1.00 43.31  ? 65  THR D N   1 
ATOM   4567 C  CA  . THR D 1 65  ? 53.735  -32.689 34.720  1.00 40.61  ? 65  THR D CA  1 
ATOM   4568 C  C   . THR D 1 65  ? 54.093  -31.877 35.960  1.00 42.42  ? 65  THR D C   1 
ATOM   4569 O  O   . THR D 1 65  ? 55.169  -32.062 36.544  1.00 42.89  ? 65  THR D O   1 
ATOM   4570 C  CB  . THR D 1 65  ? 53.918  -31.865 33.453  1.00 44.41  ? 65  THR D CB  1 
ATOM   4571 O  OG1 . THR D 1 65  ? 53.607  -32.677 32.319  1.00 41.57  ? 65  THR D OG1 1 
ATOM   4572 C  CG2 . THR D 1 65  ? 55.345  -31.358 33.337  1.00 49.26  ? 65  THR D CG2 1 
ATOM   4573 N  N   . PHE D 1 66  ? 53.191  -30.991 36.394  1.00 43.66  ? 66  PHE D N   1 
ATOM   4574 C  CA  . PHE D 1 66  ? 53.414  -30.247 37.625  1.00 42.03  ? 66  PHE D CA  1 
ATOM   4575 C  C   . PHE D 1 66  ? 53.364  -31.149 38.844  1.00 43.97  ? 66  PHE D C   1 
ATOM   4576 O  O   . PHE D 1 66  ? 54.000  -30.844 39.857  1.00 46.70  ? 66  PHE D O   1 
ATOM   4577 C  CB  . PHE D 1 66  ? 52.397  -29.114 37.766  1.00 42.84  ? 66  PHE D CB  1 
ATOM   4578 C  CG  . PHE D 1 66  ? 52.618  -28.003 36.799  1.00 50.07  ? 66  PHE D CG  1 
ATOM   4579 C  CD1 . PHE D 1 66  ? 53.737  -27.200 36.908  1.00 54.79  ? 66  PHE D CD1 1 
ATOM   4580 C  CD2 . PHE D 1 66  ? 51.735  -27.782 35.756  1.00 54.06  ? 66  PHE D CD2 1 
ATOM   4581 C  CE1 . PHE D 1 66  ? 53.965  -26.186 36.002  1.00 61.98  ? 66  PHE D CE1 1 
ATOM   4582 C  CE2 . PHE D 1 66  ? 51.958  -26.767 34.847  1.00 56.35  ? 66  PHE D CE2 1 
ATOM   4583 C  CZ  . PHE D 1 66  ? 53.073  -25.969 34.971  1.00 62.23  ? 66  PHE D CZ  1 
ATOM   4584 N  N   . MET D 1 67  ? 52.631  -32.261 38.767  1.00 43.06  ? 67  MET D N   1 
ATOM   4585 C  CA  . MET D 1 67  ? 52.598  -33.188 39.890  1.00 41.62  ? 67  MET D CA  1 
ATOM   4586 C  C   . MET D 1 67  ? 53.928  -33.922 40.036  1.00 41.62  ? 67  MET D C   1 
ATOM   4587 O  O   . MET D 1 67  ? 54.436  -34.070 41.158  1.00 40.26  ? 67  MET D O   1 
ATOM   4588 C  CB  . MET D 1 67  ? 51.433  -34.177 39.732  1.00 41.01  ? 67  MET D CB  1 
ATOM   4589 C  CG  . MET D 1 67  ? 50.045  -33.534 39.811  1.00 42.52  ? 67  MET D CG  1 
ATOM   4590 S  SD  . MET D 1 67  ? 48.619  -34.638 39.509  1.00 41.46  ? 67  MET D SD  1 
ATOM   4591 C  CE  . MET D 1 67  ? 48.554  -35.552 41.061  1.00 38.77  ? 67  MET D CE  1 
ATOM   4592 N  N   . LYS D 1 68  ? 54.499  -34.409 38.926  1.00 39.40  ? 68  LYS D N   1 
ATOM   4593 C  CA  . LYS D 1 68  ? 55.807  -35.065 39.014  1.00 44.11  ? 68  LYS D CA  1 
ATOM   4594 C  C   . LYS D 1 68  ? 56.861  -34.095 39.504  1.00 43.78  ? 68  LYS D C   1 
ATOM   4595 O  O   . LYS D 1 68  ? 57.724  -34.464 40.308  1.00 45.67  ? 68  LYS D O   1 
ATOM   4596 C  CB  . LYS D 1 68  ? 56.238  -35.666 37.667  1.00 39.89  ? 68  LYS D CB  1 
ATOM   4597 C  CG  . LYS D 1 68  ? 55.127  -36.414 36.941  1.00 57.76  ? 68  LYS D CG  1 
ATOM   4598 C  CD  . LYS D 1 68  ? 55.611  -37.394 35.881  1.00 60.91  ? 68  LYS D CD  1 
ATOM   4599 C  CE  . LYS D 1 68  ? 54.477  -37.691 34.883  1.00 56.26  ? 68  LYS D CE  1 
ATOM   4600 N  NZ  . LYS D 1 68  ? 54.943  -37.501 33.468  1.00 62.22  ? 68  LYS D NZ  1 
ATOM   4601 N  N   . TYR D 1 69  ? 56.796  -32.840 39.045  1.00 46.43  ? 69  TYR D N   1 
ATOM   4602 C  CA  . TYR D 1 69  ? 57.793  -31.864 39.468  1.00 50.97  ? 69  TYR D CA  1 
ATOM   4603 C  C   . TYR D 1 69  ? 57.654  -31.550 40.953  1.00 49.41  ? 69  TYR D C   1 
ATOM   4604 O  O   . TYR D 1 69  ? 58.658  -31.405 41.660  1.00 50.99  ? 69  TYR D O   1 
ATOM   4605 C  CB  . TYR D 1 69  ? 57.693  -30.590 38.625  1.00 47.24  ? 69  TYR D CB  1 
ATOM   4606 C  CG  . TYR D 1 69  ? 58.739  -29.569 38.997  1.00 51.96  ? 69  TYR D CG  1 
ATOM   4607 C  CD1 . TYR D 1 69  ? 60.044  -29.665 38.505  1.00 58.60  ? 69  TYR D CD1 1 
ATOM   4608 C  CD2 . TYR D 1 69  ? 58.440  -28.531 39.867  1.00 50.29  ? 69  TYR D CD2 1 
ATOM   4609 C  CE1 . TYR D 1 69  ? 61.015  -28.739 38.855  1.00 57.06  ? 69  TYR D CE1 1 
ATOM   4610 C  CE2 . TYR D 1 69  ? 59.395  -27.605 40.227  1.00 62.54  ? 69  TYR D CE2 1 
ATOM   4611 C  CZ  . TYR D 1 69  ? 60.682  -27.708 39.716  1.00 68.30  ? 69  TYR D CZ  1 
ATOM   4612 O  OH  . TYR D 1 69  ? 61.629  -26.778 40.081  1.00 70.61  ? 69  TYR D OH  1 
ATOM   4613 N  N   . GLN D 1 70  ? 56.423  -31.436 41.447  1.00 45.64  ? 70  GLN D N   1 
ATOM   4614 C  CA  . GLN D 1 70  ? 56.227  -31.284 42.881  1.00 50.37  ? 70  GLN D CA  1 
ATOM   4615 C  C   . GLN D 1 70  ? 56.941  -32.400 43.635  1.00 48.82  ? 70  GLN D C   1 
ATOM   4616 O  O   . GLN D 1 70  ? 57.781  -32.146 44.505  1.00 45.28  ? 70  GLN D O   1 
ATOM   4617 C  CB  . GLN D 1 70  ? 54.732  -31.270 43.206  1.00 46.29  ? 70  GLN D CB  1 
ATOM   4618 C  CG  . GLN D 1 70  ? 54.424  -30.989 44.654  1.00 46.71  ? 70  GLN D CG  1 
ATOM   4619 C  CD  . GLN D 1 70  ? 54.439  -29.513 44.961  1.00 47.64  ? 70  GLN D CD  1 
ATOM   4620 O  OE1 . GLN D 1 70  ? 55.501  -28.927 45.166  1.00 50.77  ? 70  GLN D OE1 1 
ATOM   4621 N  NE2 . GLN D 1 70  ? 53.263  -28.896 44.968  1.00 42.43  ? 70  GLN D NE2 1 
ATOM   4622 N  N   . ASN D 1 71  ? 56.639  -33.652 43.277  1.00 45.14  ? 71  ASN D N   1 
ATOM   4623 C  CA  . ASN D 1 71  ? 57.249  -34.785 43.966  1.00 48.82  ? 71  ASN D CA  1 
ATOM   4624 C  C   . ASN D 1 71  ? 58.762  -34.743 43.874  1.00 53.43  ? 71  ASN D C   1 
ATOM   4625 O  O   . ASN D 1 71  ? 59.468  -35.196 44.789  1.00 58.38  ? 71  ASN D O   1 
ATOM   4626 C  CB  . ASN D 1 71  ? 56.746  -36.088 43.368  1.00 37.14  ? 71  ASN D CB  1 
ATOM   4627 C  CG  . ASN D 1 71  ? 55.531  -36.593 44.065  1.00 43.76  ? 71  ASN D CG  1 
ATOM   4628 O  OD1 . ASN D 1 71  ? 55.206  -36.127 45.160  1.00 45.59  ? 71  ASN D OD1 1 
ATOM   4629 N  ND2 . ASN D 1 71  ? 54.812  -37.529 43.426  1.00 42.36  ? 71  ASN D ND2 1 
ATOM   4630 N  N   . CYS D 1 72  ? 59.262  -34.206 42.774  1.00 54.29  ? 72  CYS D N   1 
ATOM   4631 C  CA  . CYS D 1 72  ? 60.666  -34.310 42.430  1.00 65.08  ? 72  CYS D CA  1 
ATOM   4632 C  C   . CYS D 1 72  ? 61.517  -33.279 43.165  1.00 58.97  ? 72  CYS D C   1 
ATOM   4633 O  O   . CYS D 1 72  ? 62.704  -33.516 43.397  1.00 65.47  ? 72  CYS D O   1 
ATOM   4634 C  CB  . CYS D 1 72  ? 60.786  -34.191 40.911  1.00 63.20  ? 72  CYS D CB  1 
ATOM   4635 S  SG  . CYS D 1 72  ? 62.390  -33.784 40.324  1.00 88.90  ? 72  CYS D SG  1 
ATOM   4636 N  N   . ARG D 1 73  ? 60.931  -32.156 43.557  1.00 54.07  ? 73  ARG D N   1 
ATOM   4637 C  CA  . ARG D 1 73  ? 61.593  -31.187 44.409  1.00 63.81  ? 73  ARG D CA  1 
ATOM   4638 C  C   . ARG D 1 73  ? 61.268  -31.390 45.884  1.00 63.39  ? 73  ARG D C   1 
ATOM   4639 O  O   . ARG D 1 73  ? 61.592  -30.523 46.706  1.00 66.18  ? 73  ARG D O   1 
ATOM   4640 C  CB  . ARG D 1 73  ? 61.216  -29.764 43.978  1.00 67.67  ? 73  ARG D CB  1 
ATOM   4641 C  CG  . ARG D 1 73  ? 61.603  -29.436 42.544  1.00 69.30  ? 73  ARG D CG  1 
ATOM   4642 C  CD  . ARG D 1 73  ? 63.116  -29.543 42.293  1.00 69.14  ? 73  ARG D CD  1 
ATOM   4643 N  NE  . ARG D 1 73  ? 63.882  -28.570 43.075  1.00 79.55  ? 73  ARG D NE  1 
ATOM   4644 C  CZ  . ARG D 1 73  ? 63.924  -27.263 42.821  1.00 81.16  ? 73  ARG D CZ  1 
ATOM   4645 N  NH1 . ARG D 1 73  ? 63.247  -26.757 41.799  1.00 78.95  ? 73  ARG D NH1 1 
ATOM   4646 N  NH2 . ARG D 1 73  ? 64.643  -26.458 43.592  1.00 83.98  ? 73  ARG D NH2 1 
ATOM   4647 N  N   . GLY D 1 74  ? 60.617  -32.500 46.233  1.00 62.63  ? 74  GLY D N   1 
ATOM   4648 C  CA  . GLY D 1 74  ? 60.263  -32.785 47.610  1.00 62.85  ? 74  GLY D CA  1 
ATOM   4649 C  C   . GLY D 1 74  ? 59.042  -32.069 48.153  1.00 61.33  ? 74  GLY D C   1 
ATOM   4650 O  O   . GLY D 1 74  ? 58.722  -32.249 49.336  1.00 64.03  ? 74  GLY D O   1 
ATOM   4651 N  N   . GLY D 1 75  ? 58.353  -31.258 47.347  1.00 55.18  ? 75  GLY D N   1 
ATOM   4652 C  CA  . GLY D 1 75  ? 57.100  -30.667 47.779  1.00 52.57  ? 75  GLY D CA  1 
ATOM   4653 C  C   . GLY D 1 75  ? 55.993  -31.704 47.919  1.00 53.92  ? 75  GLY D C   1 
ATOM   4654 O  O   . GLY D 1 75  ? 56.136  -32.895 47.612  1.00 45.52  ? 75  GLY D O   1 
ATOM   4655 N  N   . ARG D 1 76  ? 54.843  -31.252 48.400  1.00 48.21  ? 76  ARG D N   1 
ATOM   4656 C  CA  . ARG D 1 76  ? 53.743  -32.178 48.625  1.00 54.35  ? 76  ARG D CA  1 
ATOM   4657 C  C   . ARG D 1 76  ? 52.534  -31.760 47.806  1.00 43.20  ? 76  ARG D C   1 
ATOM   4658 O  O   . ARG D 1 76  ? 52.061  -30.626 47.919  1.00 43.20  ? 76  ARG D O   1 
ATOM   4659 C  CB  . ARG D 1 76  ? 53.427  -32.306 50.117  1.00 54.69  ? 76  ARG D CB  1 
ATOM   4660 C  CG  . ARG D 1 76  ? 54.473  -33.232 50.826  1.00 63.05  ? 76  ARG D CG  1 
ATOM   4661 C  CD  . ARG D 1 76  ? 54.705  -34.553 50.033  1.00 63.37  ? 76  ARG D CD  1 
ATOM   4662 N  NE  . ARG D 1 76  ? 55.854  -35.347 50.492  1.00 63.01  ? 76  ARG D NE  1 
ATOM   4663 C  CZ  . ARG D 1 76  ? 56.912  -35.672 49.738  1.00 70.06  ? 76  ARG D CZ  1 
ATOM   4664 N  NH1 . ARG D 1 76  ? 57.009  -35.280 48.457  1.00 64.10  ? 76  ARG D NH1 1 
ATOM   4665 N  NH2 . ARG D 1 76  ? 57.889  -36.398 50.272  1.00 72.19  ? 76  ARG D NH2 1 
ATOM   4666 N  N   . ILE D 1 77  ? 52.073  -32.675 46.951  1.00 41.20  ? 77  ILE D N   1 
ATOM   4667 C  CA  . ILE D 1 77  ? 50.872  -32.463 46.150  1.00 42.46  ? 77  ILE D CA  1 
ATOM   4668 C  C   . ILE D 1 77  ? 49.674  -32.363 47.077  1.00 39.82  ? 77  ILE D C   1 
ATOM   4669 O  O   . ILE D 1 77  ? 49.387  -33.293 47.836  1.00 43.60  ? 77  ILE D O   1 
ATOM   4670 C  CB  . ILE D 1 77  ? 50.677  -33.613 45.157  1.00 40.55  ? 77  ILE D CB  1 
ATOM   4671 C  CG1 . ILE D 1 77  ? 51.811  -33.633 44.118  1.00 38.09  ? 77  ILE D CG1 1 
ATOM   4672 C  CG2 . ILE D 1 77  ? 49.297  -33.513 44.511  1.00 36.27  ? 77  ILE D CG2 1 
ATOM   4673 C  CD1 . ILE D 1 77  ? 52.147  -35.010 43.596  1.00 32.23  ? 77  ILE D CD1 1 
ATOM   4674 N  N   . VAL D 1 78  ? 48.969  -31.236 47.021  1.00 43.48  ? 78  VAL D N   1 
ATOM   4675 C  CA  . VAL D 1 78  ? 47.689  -31.073 47.699  1.00 41.30  ? 78  VAL D CA  1 
ATOM   4676 C  C   . VAL D 1 78  ? 46.638  -30.864 46.614  1.00 43.01  ? 78  VAL D C   1 
ATOM   4677 O  O   . VAL D 1 78  ? 46.657  -29.850 45.902  1.00 44.11  ? 78  VAL D O   1 
ATOM   4678 C  CB  . VAL D 1 78  ? 47.696  -29.919 48.714  1.00 42.47  ? 78  VAL D CB  1 
ATOM   4679 C  CG1 . VAL D 1 78  ? 46.341  -29.816 49.384  1.00 37.07  ? 78  VAL D CG1 1 
ATOM   4680 C  CG2 . VAL D 1 78  ? 48.769  -30.145 49.781  1.00 35.53  ? 78  VAL D CG2 1 
ATOM   4681 N  N   . LEU D 1 79  ? 45.741  -31.836 46.467  1.00 39.28  ? 79  LEU D N   1 
ATOM   4682 C  CA  . LEU D 1 79  ? 44.730  -31.828 45.413  1.00 38.41  ? 79  LEU D CA  1 
ATOM   4683 C  C   . LEU D 1 79  ? 43.424  -31.269 45.961  1.00 40.72  ? 79  LEU D C   1 
ATOM   4684 O  O   . LEU D 1 79  ? 42.970  -31.667 47.035  1.00 42.57  ? 79  LEU D O   1 
ATOM   4685 C  CB  . LEU D 1 79  ? 44.514  -33.239 44.861  1.00 32.02  ? 79  LEU D CB  1 
ATOM   4686 C  CG  . LEU D 1 79  ? 45.700  -33.807 44.088  1.00 36.62  ? 79  LEU D CG  1 
ATOM   4687 C  CD1 . LEU D 1 79  ? 45.449  -35.263 43.686  1.00 33.11  ? 79  LEU D CD1 1 
ATOM   4688 C  CD2 . LEU D 1 79  ? 46.013  -32.900 42.860  1.00 21.77  ? 79  LEU D CD2 1 
ATOM   4689 N  N   . GLN D 1 80  ? 42.814  -30.360 45.227  1.00 41.22  ? 80  GLN D N   1 
ATOM   4690 C  CA  . GLN D 1 80  ? 41.576  -29.779 45.695  1.00 38.35  ? 80  GLN D CA  1 
ATOM   4691 C  C   . GLN D 1 80  ? 40.450  -30.086 44.724  1.00 39.23  ? 80  GLN D C   1 
ATOM   4692 O  O   . GLN D 1 80  ? 40.665  -30.599 43.621  1.00 40.67  ? 80  GLN D O   1 
ATOM   4693 C  CB  . GLN D 1 80  ? 41.725  -28.276 45.888  1.00 41.37  ? 80  GLN D CB  1 
ATOM   4694 C  CG  . GLN D 1 80  ? 42.529  -27.915 47.111  1.00 51.62  ? 80  GLN D CG  1 
ATOM   4695 C  CD  . GLN D 1 80  ? 43.336  -26.659 46.887  1.00 67.73  ? 80  GLN D CD  1 
ATOM   4696 O  OE1 . GLN D 1 80  ? 42.952  -25.579 47.343  1.00 68.86  ? 80  GLN D OE1 1 
ATOM   4697 N  NE2 . GLN D 1 80  ? 44.456  -26.786 46.155  1.00 56.35  ? 80  GLN D NE2 1 
ATOM   4698 N  N   . GLN D 1 81  ? 39.240  -29.760 45.164  1.00 36.29  ? 81  GLN D N   1 
ATOM   4699 C  CA  . GLN D 1 81  ? 38.057  -29.964 44.350  1.00 34.69  ? 81  GLN D CA  1 
ATOM   4700 C  C   . GLN D 1 81  ? 38.218  -29.287 42.993  1.00 38.74  ? 81  GLN D C   1 
ATOM   4701 O  O   . GLN D 1 81  ? 38.809  -28.208 42.883  1.00 38.36  ? 81  GLN D O   1 
ATOM   4702 C  CB  . GLN D 1 81  ? 36.842  -29.393 45.069  1.00 34.74  ? 81  GLN D CB  1 
ATOM   4703 C  CG  . GLN D 1 81  ? 37.000  -27.912 45.398  1.00 33.58  ? 81  GLN D CG  1 
ATOM   4704 C  CD  . GLN D 1 81  ? 36.038  -27.470 46.478  1.00 45.30  ? 81  GLN D CD  1 
ATOM   4705 O  OE1 . GLN D 1 81  ? 35.754  -28.230 47.402  1.00 52.45  ? 81  GLN D OE1 1 
ATOM   4706 N  NE2 . GLN D 1 81  ? 35.539  -26.235 46.381  1.00 46.15  ? 81  GLN D NE2 1 
ATOM   4707 N  N   . ILE D 1 82  ? 37.677  -29.920 41.957  1.00 32.49  ? 82  ILE D N   1 
ATOM   4708 C  CA  . ILE D 1 82  ? 37.753  -29.397 40.601  1.00 35.73  ? 82  ILE D CA  1 
ATOM   4709 C  C   . ILE D 1 82  ? 36.361  -28.910 40.254  1.00 33.64  ? 82  ILE D C   1 
ATOM   4710 O  O   . ILE D 1 82  ? 35.451  -29.722 40.044  1.00 36.54  ? 82  ILE D O   1 
ATOM   4711 C  CB  . ILE D 1 82  ? 38.236  -30.449 39.591  1.00 36.75  ? 82  ILE D CB  1 
ATOM   4712 C  CG1 . ILE D 1 82  ? 39.558  -31.087 40.037  1.00 33.23  ? 82  ILE D CG1 1 
ATOM   4713 C  CG2 . ILE D 1 82  ? 38.377  -29.825 38.210  1.00 32.77  ? 82  ILE D CG2 1 
ATOM   4714 C  CD1 . ILE D 1 82  ? 39.888  -32.349 39.283  1.00 30.63  ? 82  ILE D CD1 1 
ATOM   4715 N  N   . ALA D 1 83  ? 36.191  -27.589 40.196  1.00 31.89  ? 83  ALA D N   1 
ATOM   4716 C  CA  . ALA D 1 83  ? 34.874  -27.010 39.941  1.00 37.09  ? 83  ALA D CA  1 
ATOM   4717 C  C   . ALA D 1 83  ? 34.380  -27.381 38.541  1.00 35.16  ? 83  ALA D C   1 
ATOM   4718 O  O   . ALA D 1 83  ? 35.166  -27.484 37.592  1.00 37.80  ? 83  ALA D O   1 
ATOM   4719 C  CB  . ALA D 1 83  ? 34.935  -25.480 40.103  1.00 29.84  ? 83  ALA D CB  1 
ATOM   4720 N  N   . ALA D 1 84  ? 33.077  -27.602 38.414  1.00 31.17  ? 84  ALA D N   1 
ATOM   4721 C  CA  . ALA D 1 84  ? 32.500  -27.819 37.092  1.00 34.21  ? 84  ALA D CA  1 
ATOM   4722 C  C   . ALA D 1 84  ? 32.470  -26.496 36.338  1.00 34.45  ? 84  ALA D C   1 
ATOM   4723 O  O   . ALA D 1 84  ? 32.377  -25.431 36.958  1.00 33.98  ? 84  ALA D O   1 
ATOM   4724 C  CB  . ALA D 1 84  ? 31.075  -28.373 37.193  1.00 28.68  ? 84  ALA D CB  1 
ATOM   4725 N  N   . PRO D 1 85  ? 32.523  -26.529 35.005  1.00 36.36  ? 85  PRO D N   1 
ATOM   4726 C  CA  . PRO D 1 85  ? 32.329  -25.283 34.245  1.00 38.81  ? 85  PRO D CA  1 
ATOM   4727 C  C   . PRO D 1 85  ? 31.034  -24.627 34.700  1.00 33.48  ? 85  PRO D C   1 
ATOM   4728 O  O   . PRO D 1 85  ? 30.031  -25.300 34.947  1.00 36.53  ? 85  PRO D O   1 
ATOM   4729 C  CB  . PRO D 1 85  ? 32.243  -25.749 32.779  1.00 34.06  ? 85  PRO D CB  1 
ATOM   4730 C  CG  . PRO D 1 85  ? 32.770  -27.132 32.758  1.00 34.96  ? 85  PRO D CG  1 
ATOM   4731 C  CD  . PRO D 1 85  ? 32.471  -27.717 34.134  1.00 29.94  ? 85  PRO D CD  1 
ATOM   4732 N  N   . SER D 1 86  ? 31.064  -23.309 34.844  1.00 32.41  ? 86  SER D N   1 
ATOM   4733 C  CA  . SER D 1 86  ? 29.880  -22.614 35.322  1.00 34.95  ? 86  SER D CA  1 
ATOM   4734 C  C   . SER D 1 86  ? 28.795  -22.568 34.270  1.00 41.74  ? 86  SER D C   1 
ATOM   4735 O  O   . SER D 1 86  ? 27.627  -22.375 34.611  1.00 48.47  ? 86  SER D O   1 
ATOM   4736 C  CB  . SER D 1 86  ? 30.234  -21.196 35.739  1.00 37.45  ? 86  SER D CB  1 
ATOM   4737 O  OG  . SER D 1 86  ? 30.493  -20.429 34.587  1.00 53.23  ? 86  SER D OG  1 
ATOM   4738 N  N   . MET D 1 87  ? 29.156  -22.752 33.007  1.00 39.96  ? 87  MET D N   1 
ATOM   4739 C  CA  . MET D 1 87  ? 28.224  -22.610 31.900  1.00 41.19  ? 87  MET D CA  1 
ATOM   4740 C  C   . MET D 1 87  ? 28.506  -23.731 30.910  1.00 40.24  ? 87  MET D C   1 
ATOM   4741 O  O   . MET D 1 87  ? 29.537  -23.723 30.231  1.00 42.77  ? 87  MET D O   1 
ATOM   4742 C  CB  . MET D 1 87  ? 28.374  -21.232 31.252  1.00 44.12  ? 87  MET D CB  1 
ATOM   4743 C  CG  . MET D 1 87  ? 27.057  -20.639 30.797  1.00 53.89  ? 87  MET D CG  1 
ATOM   4744 S  SD  . MET D 1 87  ? 26.751  -21.266 29.159  1.00 71.26  ? 87  MET D SD  1 
ATOM   4745 C  CE  . MET D 1 87  ? 28.362  -20.913 28.391  1.00 48.17  ? 87  MET D CE  1 
ATOM   4746 N  N   . ARG D 1 88  ? 27.598  -24.692 30.822  1.00 42.21  ? 88  ARG D N   1 
ATOM   4747 C  CA  . ARG D 1 88  ? 27.812  -25.869 29.996  1.00 39.21  ? 88  ARG D CA  1 
ATOM   4748 C  C   . ARG D 1 88  ? 26.987  -25.877 28.713  1.00 41.78  ? 88  ARG D C   1 
ATOM   4749 O  O   . ARG D 1 88  ? 27.135  -26.801 27.914  1.00 41.69  ? 88  ARG D O   1 
ATOM   4750 C  CB  . ARG D 1 88  ? 27.536  -27.118 30.830  1.00 35.64  ? 88  ARG D CB  1 
ATOM   4751 C  CG  . ARG D 1 88  ? 28.432  -27.218 32.099  1.00 33.54  ? 88  ARG D CG  1 
ATOM   4752 C  CD  . ARG D 1 88  ? 28.202  -28.524 32.943  1.00 25.76  ? 88  ARG D CD  1 
ATOM   4753 N  NE  . ARG D 1 88  ? 27.790  -29.685 32.131  1.00 36.08  ? 88  ARG D NE  1 
ATOM   4754 C  CZ  . ARG D 1 88  ? 28.371  -30.146 30.992  1.00 50.92  ? 88  ARG D CZ  1 
ATOM   4755 N  NH1 . ARG D 1 88  ? 27.870  -31.200 30.362  1.00 53.53  ? 88  ARG D NH1 1 
ATOM   4756 N  NH2 . ARG D 1 88  ? 29.428  -29.575 30.426  1.00 46.99  ? 88  ARG D NH2 1 
ATOM   4757 N  N   . GLU D 1 89  ? 26.129  -24.877 28.488  1.00 47.33  ? 89  GLU D N   1 
ATOM   4758 C  CA  . GLU D 1 89  ? 25.534  -24.634 27.170  1.00 47.98  ? 89  GLU D CA  1 
ATOM   4759 C  C   . GLU D 1 89  ? 26.503  -23.766 26.374  1.00 46.30  ? 89  GLU D C   1 
ATOM   4760 O  O   . GLU D 1 89  ? 26.413  -22.540 26.367  1.00 50.61  ? 89  GLU D O   1 
ATOM   4761 C  CB  . GLU D 1 89  ? 24.169  -23.962 27.290  1.00 52.01  ? 89  GLU D CB  1 
ATOM   4762 C  CG  . GLU D 1 89  ? 23.085  -24.835 27.915  1.00 53.51  ? 89  GLU D CG  1 
ATOM   4763 C  CD  . GLU D 1 89  ? 22.702  -26.001 27.023  1.00 62.71  ? 89  GLU D CD  1 
ATOM   4764 O  OE1 . GLU D 1 89  ? 22.501  -27.116 27.554  1.00 62.13  ? 89  GLU D OE1 1 
ATOM   4765 O  OE2 . GLU D 1 89  ? 22.609  -25.802 25.787  1.00 68.34  ? 89  GLU D OE2 1 
ATOM   4766 N  N   . TRP D 1 90  ? 27.440  -24.404 25.682  1.00 37.69  ? 90  TRP D N   1 
ATOM   4767 C  CA  . TRP D 1 90  ? 28.473  -23.634 25.011  1.00 40.78  ? 90  TRP D CA  1 
ATOM   4768 C  C   . TRP D 1 90  ? 27.975  -22.930 23.764  1.00 41.28  ? 90  TRP D C   1 
ATOM   4769 O  O   . TRP D 1 90  ? 28.692  -22.074 23.246  1.00 45.54  ? 90  TRP D O   1 
ATOM   4770 C  CB  . TRP D 1 90  ? 29.653  -24.537 24.661  1.00 41.02  ? 90  TRP D CB  1 
ATOM   4771 C  CG  . TRP D 1 90  ? 30.166  -25.189 25.855  1.00 35.79  ? 90  TRP D CG  1 
ATOM   4772 C  CD1 . TRP D 1 90  ? 29.923  -26.475 26.278  1.00 37.07  ? 90  TRP D CD1 1 
ATOM   4773 C  CD2 . TRP D 1 90  ? 30.977  -24.582 26.846  1.00 34.96  ? 90  TRP D CD2 1 
ATOM   4774 N  NE1 . TRP D 1 90  ? 30.569  -26.706 27.470  1.00 34.86  ? 90  TRP D NE1 1 
ATOM   4775 C  CE2 . TRP D 1 90  ? 31.216  -25.554 27.845  1.00 37.44  ? 90  TRP D CE2 1 
ATOM   4776 C  CE3 . TRP D 1 90  ? 31.535  -23.309 26.989  1.00 36.38  ? 90  TRP D CE3 1 
ATOM   4777 C  CZ2 . TRP D 1 90  ? 31.990  -25.286 28.970  1.00 37.05  ? 90  TRP D CZ2 1 
ATOM   4778 C  CZ3 . TRP D 1 90  ? 32.301  -23.038 28.113  1.00 35.11  ? 90  TRP D CZ3 1 
ATOM   4779 C  CH2 . TRP D 1 90  ? 32.531  -24.032 29.083  1.00 41.63  ? 90  TRP D CH2 1 
ATOM   4780 N  N   . GLY D 1 91  ? 26.799  -23.265 23.261  1.00 39.28  ? 91  GLY D N   1 
ATOM   4781 C  CA  . GLY D 1 91  ? 26.256  -22.531 22.127  1.00 38.44  ? 91  GLY D CA  1 
ATOM   4782 C  C   . GLY D 1 91  ? 26.851  -23.007 20.824  1.00 43.01  ? 91  GLY D C   1 
ATOM   4783 O  O   . GLY D 1 91  ? 26.910  -24.211 20.574  1.00 47.82  ? 91  GLY D O   1 
ATOM   4784 N  N   . THR D 1 92  ? 27.297  -22.065 19.979  1.00 41.06  ? 92  THR D N   1 
ATOM   4785 C  CA  . THR D 1 92  ? 27.848  -22.415 18.676  1.00 45.16  ? 92  THR D CA  1 
ATOM   4786 C  C   . THR D 1 92  ? 29.267  -22.938 18.821  1.00 43.85  ? 92  THR D C   1 
ATOM   4787 O  O   . THR D 1 92  ? 29.888  -22.845 19.883  1.00 45.29  ? 92  THR D O   1 
ATOM   4788 C  CB  . THR D 1 92  ? 27.887  -21.213 17.736  1.00 49.88  ? 92  THR D CB  1 
ATOM   4789 O  OG1 . THR D 1 92  ? 28.723  -20.198 18.320  1.00 45.92  ? 92  THR D OG1 1 
ATOM   4790 C  CG2 . THR D 1 92  ? 26.457  -20.662 17.466  1.00 41.22  ? 92  THR D CG2 1 
ATOM   4791 N  N   . GLY D 1 93  ? 29.791  -23.476 17.719  1.00 39.48  ? 93  GLY D N   1 
ATOM   4792 C  CA  . GLY D 1 93  ? 31.200  -23.821 17.692  1.00 41.27  ? 93  GLY D CA  1 
ATOM   4793 C  C   . GLY D 1 93  ? 32.084  -22.611 17.935  1.00 41.26  ? 93  GLY D C   1 
ATOM   4794 O  O   . GLY D 1 93  ? 33.134  -22.712 18.576  1.00 39.94  ? 93  GLY D O   1 
ATOM   4795 N  N   . LEU D 1 94  ? 31.662  -21.449 17.436  1.00 38.07  ? 94  LEU D N   1 
ATOM   4796 C  CA  . LEU D 1 94  ? 32.454  -20.243 17.601  1.00 37.37  ? 94  LEU D CA  1 
ATOM   4797 C  C   . LEU D 1 94  ? 32.486  -19.803 19.061  1.00 42.86  ? 94  LEU D C   1 
ATOM   4798 O  O   . LEU D 1 94  ? 33.553  -19.451 19.579  1.00 41.36  ? 94  LEU D O   1 
ATOM   4799 C  CB  . LEU D 1 94  ? 31.914  -19.126 16.707  1.00 28.14  ? 94  LEU D CB  1 
ATOM   4800 C  CG  . LEU D 1 94  ? 32.697  -17.803 16.830  1.00 43.29  ? 94  LEU D CG  1 
ATOM   4801 C  CD1 . LEU D 1 94  ? 34.187  -17.935 16.412  1.00 37.40  ? 94  LEU D CD1 1 
ATOM   4802 C  CD2 . LEU D 1 94  ? 32.033  -16.707 16.048  1.00 33.92  ? 94  LEU D CD2 1 
ATOM   4803 N  N   . GLU D 1 95  ? 31.335  -19.822 19.750  1.00 44.93  ? 95  GLU D N   1 
ATOM   4804 C  CA  . GLU D 1 95  ? 31.324  -19.418 21.158  1.00 38.67  ? 95  GLU D CA  1 
ATOM   4805 C  C   . GLU D 1 95  ? 32.212  -20.328 21.992  1.00 35.95  ? 95  GLU D C   1 
ATOM   4806 O  O   . GLU D 1 95  ? 32.947  -19.856 22.866  1.00 39.72  ? 95  GLU D O   1 
ATOM   4807 C  CB  . GLU D 1 95  ? 29.903  -19.413 21.711  1.00 36.14  ? 95  GLU D CB  1 
ATOM   4808 C  CG  . GLU D 1 95  ? 29.038  -18.224 21.269  1.00 41.78  ? 95  GLU D CG  1 
ATOM   4809 C  CD  . GLU D 1 95  ? 27.531  -18.486 21.444  1.00 52.21  ? 95  GLU D CD  1 
ATOM   4810 O  OE1 . GLU D 1 95  ? 27.044  -19.561 21.013  1.00 56.77  ? 95  GLU D OE1 1 
ATOM   4811 O  OE2 . GLU D 1 95  ? 26.830  -17.628 22.011  1.00 53.54  ? 95  GLU D OE2 1 
ATOM   4812 N  N   . ALA D 1 96  ? 32.189  -21.630 21.716  1.00 33.60  ? 96  ALA D N   1 
ATOM   4813 C  CA  . ALA D 1 96  ? 33.076  -22.530 22.443  1.00 40.22  ? 96  ALA D CA  1 
ATOM   4814 C  C   . ALA D 1 96  ? 34.547  -22.202 22.177  1.00 41.53  ? 96  ALA D C   1 
ATOM   4815 O  O   . ALA D 1 96  ? 35.373  -22.250 23.102  1.00 37.29  ? 96  ALA D O   1 
ATOM   4816 C  CB  . ALA D 1 96  ? 32.769  -23.984 22.092  1.00 35.58  ? 96  ALA D CB  1 
ATOM   4817 N  N   . LEU D 1 97  ? 34.900  -21.865 20.925  1.00 36.92  ? 97  LEU D N   1 
ATOM   4818 C  CA  . LEU D 1 97  ? 36.297  -21.541 20.632  1.00 33.89  ? 97  LEU D CA  1 
ATOM   4819 C  C   . LEU D 1 97  ? 36.723  -20.276 21.365  1.00 36.68  ? 97  LEU D C   1 
ATOM   4820 O  O   . LEU D 1 97  ? 37.851  -20.197 21.862  1.00 36.41  ? 97  LEU D O   1 
ATOM   4821 C  CB  . LEU D 1 97  ? 36.522  -21.378 19.126  1.00 35.13  ? 97  LEU D CB  1 
ATOM   4822 C  CG  . LEU D 1 97  ? 36.442  -22.643 18.274  1.00 38.11  ? 97  LEU D CG  1 
ATOM   4823 C  CD1 . LEU D 1 97  ? 36.639  -22.302 16.781  1.00 33.42  ? 97  LEU D CD1 1 
ATOM   4824 C  CD2 . LEU D 1 97  ? 37.452  -23.670 18.768  1.00 30.90  ? 97  LEU D CD2 1 
ATOM   4825 N  N   . GLN D 1 98  ? 35.828  -19.284 21.457  1.00 36.14  ? 98  GLN D N   1 
ATOM   4826 C  CA  . GLN D 1 98  ? 36.135  -18.069 22.211  1.00 34.67  ? 98  GLN D CA  1 
ATOM   4827 C  C   . GLN D 1 98  ? 36.305  -18.372 23.684  1.00 35.42  ? 98  GLN D C   1 
ATOM   4828 O  O   . GLN D 1 98  ? 37.286  -17.937 24.301  1.00 42.93  ? 98  GLN D O   1 
ATOM   4829 C  CB  . GLN D 1 98  ? 35.056  -17.007 22.007  1.00 29.38  ? 98  GLN D CB  1 
ATOM   4830 C  CG  . GLN D 1 98  ? 35.369  -16.122 20.809  1.00 48.62  ? 98  GLN D CG  1 
ATOM   4831 C  CD  . GLN D 1 98  ? 34.134  -15.650 20.052  1.00 60.12  ? 98  GLN D CD  1 
ATOM   4832 O  OE1 . GLN D 1 98  ? 33.016  -16.158 20.260  1.00 54.66  ? 98  GLN D OE1 1 
ATOM   4833 N  NE2 . GLN D 1 98  ? 34.341  -14.707 19.120  1.00 53.01  ? 98  GLN D NE2 1 
ATOM   4834 N  N   . ALA D 1 99  ? 35.366  -19.119 24.274  1.00 31.35  ? 99  ALA D N   1 
ATOM   4835 C  CA  . ALA D 1 99  ? 35.543  -19.504 25.668  1.00 32.78  ? 99  ALA D CA  1 
ATOM   4836 C  C   . ALA D 1 99  ? 36.854  -20.260 25.844  1.00 35.10  ? 99  ALA D C   1 
ATOM   4837 O  O   . ALA D 1 99  ? 37.577  -20.043 26.824  1.00 34.69  ? 99  ALA D O   1 
ATOM   4838 C  CB  . ALA D 1 99  ? 34.358  -20.342 26.152  1.00 26.65  ? 99  ALA D CB  1 
ATOM   4839 N  N   . ALA D 1 100 ? 37.213  -21.095 24.864  1.00 31.77  ? 100 ALA D N   1 
ATOM   4840 C  CA  . ALA D 1 100 ? 38.434  -21.885 24.979  1.00 43.39  ? 100 ALA D CA  1 
ATOM   4841 C  C   . ALA D 1 100 ? 39.667  -20.990 24.941  1.00 42.98  ? 100 ALA D C   1 
ATOM   4842 O  O   . ALA D 1 100 ? 40.595  -21.158 25.751  1.00 35.73  ? 100 ALA D O   1 
ATOM   4843 C  CB  . ALA D 1 100 ? 38.490  -22.946 23.874  1.00 36.63  ? 100 ALA D CB  1 
ATOM   4844 N  N   . LEU D 1 101 ? 39.687  -20.033 23.999  1.00 40.03  ? 101 LEU D N   1 
ATOM   4845 C  CA  . LEU D 1 101 ? 40.773  -19.058 23.911  1.00 39.95  ? 101 LEU D CA  1 
ATOM   4846 C  C   . LEU D 1 101 ? 40.963  -18.318 25.228  1.00 42.88  ? 101 LEU D C   1 
ATOM   4847 O  O   . LEU D 1 101 ? 42.097  -18.119 25.683  1.00 41.91  ? 101 LEU D O   1 
ATOM   4848 C  CB  . LEU D 1 101 ? 40.504  -18.046 22.781  1.00 40.45  ? 101 LEU D CB  1 
ATOM   4849 C  CG  . LEU D 1 101 ? 41.557  -16.925 22.648  1.00 41.78  ? 101 LEU D CG  1 
ATOM   4850 C  CD1 . LEU D 1 101 ? 42.910  -17.504 22.214  1.00 35.81  ? 101 LEU D CD1 1 
ATOM   4851 C  CD2 . LEU D 1 101 ? 41.096  -15.827 21.705  1.00 38.27  ? 101 LEU D CD2 1 
ATOM   4852 N  N   . ASP D 1 102 ? 39.852  -17.875 25.835  1.00 43.11  ? 102 ASP D N   1 
ATOM   4853 C  CA  . ASP D 1 102 ? 39.914  -17.174 27.117  1.00 41.09  ? 102 ASP D CA  1 
ATOM   4854 C  C   . ASP D 1 102 ? 40.458  -18.076 28.207  1.00 38.31  ? 102 ASP D C   1 
ATOM   4855 O  O   . ASP D 1 102 ? 41.278  -17.644 29.031  1.00 42.07  ? 102 ASP D O   1 
ATOM   4856 C  CB  . ASP D 1 102 ? 38.528  -16.658 27.508  1.00 34.57  ? 102 ASP D CB  1 
ATOM   4857 C  CG  . ASP D 1 102 ? 38.082  -15.500 26.643  1.00 51.76  ? 102 ASP D CG  1 
ATOM   4858 O  OD1 . ASP D 1 102 ? 38.935  -14.982 25.879  1.00 52.80  ? 102 ASP D OD1 1 
ATOM   4859 O  OD2 . ASP D 1 102 ? 36.886  -15.116 26.708  1.00 59.15  ? 102 ASP D OD2 1 
ATOM   4860 N  N   . LEU D 1 103 ? 40.005  -19.330 28.232  1.00 38.01  ? 103 LEU D N   1 
ATOM   4861 C  CA  . LEU D 1 103 ? 40.561  -20.318 29.157  1.00 40.64  ? 103 LEU D CA  1 
ATOM   4862 C  C   . LEU D 1 103 ? 42.071  -20.457 28.984  1.00 38.72  ? 103 LEU D C   1 
ATOM   4863 O  O   . LEU D 1 103 ? 42.819  -20.472 29.969  1.00 41.66  ? 103 LEU D O   1 
ATOM   4864 C  CB  . LEU D 1 103 ? 39.874  -21.665 28.952  1.00 32.85  ? 103 LEU D CB  1 
ATOM   4865 C  CG  . LEU D 1 103 ? 40.383  -22.795 29.828  1.00 36.59  ? 103 LEU D CG  1 
ATOM   4866 C  CD1 . LEU D 1 103 ? 40.164  -22.466 31.294  1.00 32.89  ? 103 LEU D CD1 1 
ATOM   4867 C  CD2 . LEU D 1 103 ? 39.673  -24.076 29.445  1.00 39.69  ? 103 LEU D CD2 1 
ATOM   4868 N  N   . GLU D 1 104 ? 42.539  -20.574 27.732  1.00 42.22  ? 104 GLU D N   1 
ATOM   4869 C  CA  . GLU D 1 104 ? 43.970  -20.742 27.494  1.00 45.57  ? 104 GLU D CA  1 
ATOM   4870 C  C   . GLU D 1 104 ? 44.748  -19.569 28.051  1.00 46.80  ? 104 GLU D C   1 
ATOM   4871 O  O   . GLU D 1 104 ? 45.804  -19.755 28.665  1.00 49.52  ? 104 GLU D O   1 
ATOM   4872 C  CB  . GLU D 1 104 ? 44.266  -20.892 26.005  1.00 42.29  ? 104 GLU D CB  1 
ATOM   4873 C  CG  . GLU D 1 104 ? 43.752  -22.158 25.388  1.00 52.68  ? 104 GLU D CG  1 
ATOM   4874 C  CD  . GLU D 1 104 ? 44.585  -23.376 25.730  1.00 58.44  ? 104 GLU D CD  1 
ATOM   4875 O  OE1 . GLU D 1 104 ? 45.396  -23.794 24.878  1.00 75.96  ? 104 GLU D OE1 1 
ATOM   4876 O  OE2 . GLU D 1 104 ? 44.395  -23.956 26.816  1.00 59.26  ? 104 GLU D OE2 1 
ATOM   4877 N  N   . LYS D 1 105 ? 44.229  -18.352 27.860  1.00 42.70  ? 105 LYS D N   1 
ATOM   4878 C  CA  . LYS D 1 105 ? 44.924  -17.171 28.345  1.00 44.23  ? 105 LYS D CA  1 
ATOM   4879 C  C   . LYS D 1 105 ? 44.895  -17.101 29.862  1.00 50.21  ? 105 LYS D C   1 
ATOM   4880 O  O   . LYS D 1 105 ? 45.869  -16.649 30.479  1.00 52.25  ? 105 LYS D O   1 
ATOM   4881 C  CB  . LYS D 1 105 ? 44.320  -15.919 27.722  1.00 42.95  ? 105 LYS D CB  1 
ATOM   4882 C  CG  . LYS D 1 105 ? 44.352  -15.970 26.206  1.00 54.46  ? 105 LYS D CG  1 
ATOM   4883 C  CD  . LYS D 1 105 ? 44.526  -14.613 25.562  1.00 57.47  ? 105 LYS D CD  1 
ATOM   4884 C  CE  . LYS D 1 105 ? 43.233  -13.832 25.551  1.00 48.87  ? 105 LYS D CE  1 
ATOM   4885 N  NZ  . LYS D 1 105 ? 43.370  -12.726 24.570  1.00 63.03  ? 105 LYS D NZ  1 
ATOM   4886 N  N   . GLN D 1 106 ? 43.815  -17.574 30.481  1.00 43.77  ? 106 GLN D N   1 
ATOM   4887 C  CA  . GLN D 1 106 ? 43.762  -17.602 31.936  1.00 46.70  ? 106 GLN D CA  1 
ATOM   4888 C  C   . GLN D 1 106 ? 44.810  -18.558 32.491  1.00 49.57  ? 106 GLN D C   1 
ATOM   4889 O  O   . GLN D 1 106 ? 45.544  -18.219 33.429  1.00 50.07  ? 106 GLN D O   1 
ATOM   4890 C  CB  . GLN D 1 106 ? 42.363  -17.997 32.402  1.00 42.85  ? 106 GLN D CB  1 
ATOM   4891 C  CG  . GLN D 1 106 ? 42.267  -18.297 33.879  1.00 58.56  ? 106 GLN D CG  1 
ATOM   4892 C  CD  . GLN D 1 106 ? 40.830  -18.482 34.344  1.00 68.01  ? 106 GLN D CD  1 
ATOM   4893 O  OE1 . GLN D 1 106 ? 39.915  -18.625 33.528  1.00 64.76  ? 106 GLN D OE1 1 
ATOM   4894 N  NE2 . GLN D 1 106 ? 40.627  -18.476 35.659  1.00 70.25  ? 106 GLN D NE2 1 
ATOM   4895 N  N   . VAL D 1 107 ? 44.907  -19.755 31.903  1.00 48.07  ? 107 VAL D N   1 
ATOM   4896 C  CA  . VAL D 1 107 ? 45.914  -20.718 32.335  1.00 47.75  ? 107 VAL D CA  1 
ATOM   4897 C  C   . VAL D 1 107 ? 47.306  -20.137 32.157  1.00 51.78  ? 107 VAL D C   1 
ATOM   4898 O  O   . VAL D 1 107 ? 48.178  -20.293 33.023  1.00 52.72  ? 107 VAL D O   1 
ATOM   4899 C  CB  . VAL D 1 107 ? 45.753  -22.041 31.569  1.00 47.76  ? 107 VAL D CB  1 
ATOM   4900 C  CG1 . VAL D 1 107 ? 46.994  -22.916 31.750  1.00 45.69  ? 107 VAL D CG1 1 
ATOM   4901 C  CG2 . VAL D 1 107 ? 44.491  -22.766 32.026  1.00 44.08  ? 107 VAL D CG2 1 
ATOM   4902 N  N   . ASN D 1 108 ? 47.519  -19.415 31.053  1.00 49.26  ? 108 ASN D N   1 
ATOM   4903 C  CA  . ASN D 1 108 ? 48.831  -18.861 30.772  1.00 51.45  ? 108 ASN D CA  1 
ATOM   4904 C  C   . ASN D 1 108 ? 49.133  -17.637 31.618  1.00 54.23  ? 108 ASN D C   1 
ATOM   4905 O  O   . ASN D 1 108 ? 50.300  -17.402 31.948  1.00 50.63  ? 108 ASN D O   1 
ATOM   4906 C  CB  . ASN D 1 108 ? 48.954  -18.558 29.284  1.00 55.38  ? 108 ASN D CB  1 
ATOM   4907 C  CG  . ASN D 1 108 ? 49.331  -19.792 28.496  1.00 69.78  ? 108 ASN D CG  1 
ATOM   4908 O  OD1 . ASN D 1 108 ? 50.515  -20.062 28.272  1.00 81.64  ? 108 ASN D OD1 1 
ATOM   4909 N  ND2 . ASN D 1 108 ? 48.326  -20.585 28.114  1.00 66.91  ? 108 ASN D ND2 1 
ATOM   4910 N  N   . GLN D 1 109 ? 48.113  -16.859 31.988  1.00 54.63  ? 109 GLN D N   1 
ATOM   4911 C  CA  . GLN D 1 109 ? 48.323  -15.801 32.971  1.00 54.71  ? 109 GLN D CA  1 
ATOM   4912 C  C   . GLN D 1 109 ? 48.789  -16.385 34.292  1.00 55.55  ? 109 GLN D C   1 
ATOM   4913 O  O   . GLN D 1 109 ? 49.751  -15.901 34.898  1.00 58.05  ? 109 GLN D O   1 
ATOM   4914 C  CB  . GLN D 1 109 ? 47.044  -14.990 33.182  1.00 57.51  ? 109 GLN D CB  1 
ATOM   4915 C  CG  . GLN D 1 109 ? 47.308  -13.615 33.763  1.00 61.96  ? 109 GLN D CG  1 
ATOM   4916 C  CD  . GLN D 1 109 ? 48.381  -12.873 32.975  1.00 69.82  ? 109 GLN D CD  1 
ATOM   4917 O  OE1 . GLN D 1 109 ? 49.493  -12.654 33.469  1.00 67.33  ? 109 GLN D OE1 1 
ATOM   4918 N  NE2 . GLN D 1 109 ? 48.058  -12.497 31.736  1.00 65.65  ? 109 GLN D NE2 1 
ATOM   4919 N  N   . SER D 1 110 ? 48.116  -17.441 34.748  1.00 54.85  ? 110 SER D N   1 
ATOM   4920 C  CA  . SER D 1 110 ? 48.494  -18.066 36.007  1.00 50.26  ? 110 SER D CA  1 
ATOM   4921 C  C   . SER D 1 110 ? 49.913  -18.614 35.937  1.00 56.02  ? 110 SER D C   1 
ATOM   4922 O  O   . SER D 1 110 ? 50.687  -18.480 36.893  1.00 53.28  ? 110 SER D O   1 
ATOM   4923 C  CB  . SER D 1 110 ? 47.495  -19.161 36.355  1.00 45.14  ? 110 SER D CB  1 
ATOM   4924 O  OG  . SER D 1 110 ? 48.125  -20.226 37.034  1.00 50.15  ? 110 SER D OG  1 
ATOM   4925 N  N   . LEU D 1 111 ? 50.277  -19.227 34.807  1.00 54.22  ? 111 LEU D N   1 
ATOM   4926 C  CA  . LEU D 1 111 ? 51.647  -19.700 34.641  1.00 54.93  ? 111 LEU D CA  1 
ATOM   4927 C  C   . LEU D 1 111 ? 52.631  -18.543 34.703  1.00 57.98  ? 111 LEU D C   1 
ATOM   4928 O  O   . LEU D 1 111 ? 53.704  -18.664 35.310  1.00 52.69  ? 111 LEU D O   1 
ATOM   4929 C  CB  . LEU D 1 111 ? 51.795  -20.435 33.313  1.00 49.10  ? 111 LEU D CB  1 
ATOM   4930 C  CG  . LEU D 1 111 ? 51.575  -21.940 33.324  1.00 59.27  ? 111 LEU D CG  1 
ATOM   4931 C  CD1 . LEU D 1 111 ? 51.112  -22.426 31.947  1.00 67.24  ? 111 LEU D CD1 1 
ATOM   4932 C  CD2 . LEU D 1 111 ? 52.850  -22.627 33.746  1.00 63.09  ? 111 LEU D CD2 1 
ATOM   4933 N  N   . LEU D 1 112 ? 52.279  -17.412 34.076  1.00 49.02  ? 112 LEU D N   1 
ATOM   4934 C  CA  . LEU D 1 112 ? 53.183  -16.267 34.034  1.00 55.55  ? 112 LEU D CA  1 
ATOM   4935 C  C   . LEU D 1 112 ? 53.407  -15.700 35.432  1.00 57.59  ? 112 LEU D C   1 
ATOM   4936 O  O   . LEU D 1 112 ? 54.522  -15.284 35.767  1.00 52.73  ? 112 LEU D O   1 
ATOM   4937 C  CB  . LEU D 1 112 ? 52.637  -15.190 33.089  1.00 54.11  ? 112 LEU D CB  1 
ATOM   4938 C  CG  . LEU D 1 112 ? 53.494  -13.919 32.978  1.00 62.12  ? 112 LEU D CG  1 
ATOM   4939 C  CD1 . LEU D 1 112 ? 54.721  -14.186 32.116  1.00 68.83  ? 112 LEU D CD1 1 
ATOM   4940 C  CD2 . LEU D 1 112 ? 52.723  -12.713 32.454  1.00 56.74  ? 112 LEU D CD2 1 
ATOM   4941 N  N   . GLU D 1 113 ? 52.359  -15.678 36.260  1.00 57.50  ? 113 GLU D N   1 
ATOM   4942 C  CA  . GLU D 1 113 ? 52.531  -15.296 37.654  1.00 61.72  ? 113 GLU D CA  1 
ATOM   4943 C  C   . GLU D 1 113 ? 53.310  -16.356 38.417  1.00 56.95  ? 113 GLU D C   1 
ATOM   4944 O  O   . GLU D 1 113 ? 54.085  -16.026 39.322  1.00 57.90  ? 113 GLU D O   1 
ATOM   4945 C  CB  . GLU D 1 113 ? 51.168  -15.042 38.304  1.00 59.30  ? 113 GLU D CB  1 
ATOM   4946 C  CG  . GLU D 1 113 ? 50.525  -13.739 37.855  1.00 65.60  ? 113 GLU D CG  1 
ATOM   4947 C  CD  . GLU D 1 113 ? 49.003  -13.776 37.929  1.00 78.78  ? 113 GLU D CD  1 
ATOM   4948 O  OE1 . GLU D 1 113 ? 48.452  -14.595 38.707  1.00 65.40  ? 113 GLU D OE1 1 
ATOM   4949 O  OE2 . GLU D 1 113 ? 48.360  -12.994 37.185  1.00 84.69  ? 113 GLU D OE2 1 
ATOM   4950 N  N   . LEU D 1 114 ? 53.127  -17.627 38.067  1.00 55.45  ? 114 LEU D N   1 
ATOM   4951 C  CA  . LEU D 1 114 ? 53.969  -18.660 38.651  1.00 58.37  ? 114 LEU D CA  1 
ATOM   4952 C  C   . LEU D 1 114 ? 55.432  -18.413 38.314  1.00 62.22  ? 114 LEU D C   1 
ATOM   4953 O  O   . LEU D 1 114 ? 56.319  -18.737 39.111  1.00 59.91  ? 114 LEU D O   1 
ATOM   4954 C  CB  . LEU D 1 114 ? 53.528  -20.038 38.163  1.00 51.19  ? 114 LEU D CB  1 
ATOM   4955 C  CG  . LEU D 1 114 ? 54.393  -21.195 38.638  1.00 49.96  ? 114 LEU D CG  1 
ATOM   4956 C  CD1 . LEU D 1 114 ? 54.338  -21.270 40.131  1.00 48.65  ? 114 LEU D CD1 1 
ATOM   4957 C  CD2 . LEU D 1 114 ? 53.948  -22.493 38.024  1.00 54.83  ? 114 LEU D CD2 1 
ATOM   4958 N  N   . HIS D 1 115 ? 55.696  -17.806 37.150  1.00 62.72  ? 115 HIS D N   1 
ATOM   4959 C  CA  . HIS D 1 115 ? 57.064  -17.561 36.712  1.00 61.54  ? 115 HIS D CA  1 
ATOM   4960 C  C   . HIS D 1 115 ? 57.732  -16.424 37.474  1.00 60.19  ? 115 HIS D C   1 
ATOM   4961 O  O   . HIS D 1 115 ? 58.955  -16.439 37.631  1.00 62.12  ? 115 HIS D O   1 
ATOM   4962 C  CB  . HIS D 1 115 ? 57.095  -17.257 35.221  1.00 54.16  ? 115 HIS D CB  1 
ATOM   4963 C  CG  . HIS D 1 115 ? 58.477  -17.129 34.669  1.00 59.09  ? 115 HIS D CG  1 
ATOM   4964 N  ND1 . HIS D 1 115 ? 59.138  -15.921 34.599  1.00 59.97  ? 115 HIS D ND1 1 
ATOM   4965 C  CD2 . HIS D 1 115 ? 59.326  -18.056 34.164  1.00 63.22  ? 115 HIS D CD2 1 
ATOM   4966 C  CE1 . HIS D 1 115 ? 60.339  -16.113 34.080  1.00 62.53  ? 115 HIS D CE1 1 
ATOM   4967 N  NE2 . HIS D 1 115 ? 60.475  -17.397 33.798  1.00 59.67  ? 115 HIS D NE2 1 
ATOM   4968 N  N   . SER D 1 116 ? 56.964  -15.430 37.931  1.00 54.76  ? 116 SER D N   1 
ATOM   4969 C  CA  . SER D 1 116 ? 57.535  -14.347 38.729  1.00 61.75  ? 116 SER D CA  1 
ATOM   4970 C  C   . SER D 1 116 ? 57.840  -14.789 40.155  1.00 69.62  ? 116 SER D C   1 
ATOM   4971 O  O   . SER D 1 116 ? 58.894  -14.444 40.700  1.00 71.24  ? 116 SER D O   1 
ATOM   4972 C  CB  . SER D 1 116 ? 56.594  -13.149 38.752  1.00 55.93  ? 116 SER D CB  1 
ATOM   4973 O  OG  . SER D 1 116 ? 56.577  -12.509 37.493  1.00 75.96  ? 116 SER D OG  1 
ATOM   4974 N  N   . THR D 1 117 ? 56.923  -15.529 40.781  1.00 65.86  ? 117 THR D N   1 
ATOM   4975 C  CA  . THR D 1 117 ? 57.174  -16.043 42.121  1.00 64.87  ? 117 THR D CA  1 
ATOM   4976 C  C   . THR D 1 117 ? 58.439  -16.891 42.145  1.00 66.03  ? 117 THR D C   1 
ATOM   4977 O  O   . THR D 1 117 ? 59.300  -16.715 43.017  1.00 72.28  ? 117 THR D O   1 
ATOM   4978 C  CB  . THR D 1 117 ? 55.953  -16.834 42.607  1.00 64.71  ? 117 THR D CB  1 
ATOM   4979 O  OG1 . THR D 1 117 ? 54.829  -15.950 42.709  1.00 72.08  ? 117 THR D OG1 1 
ATOM   4980 C  CG2 . THR D 1 117 ? 56.206  -17.471 43.960  1.00 64.82  ? 117 THR D CG2 1 
ATOM   4981 N  N   . ALA D 1 118 ? 58.580  -17.801 41.174  1.00 65.48  ? 118 ALA D N   1 
ATOM   4982 C  CA  . ALA D 1 118 ? 59.801  -18.592 41.028  1.00 67.27  ? 118 ALA D CA  1 
ATOM   4983 C  C   . ALA D 1 118 ? 61.018  -17.737 40.679  1.00 70.32  ? 118 ALA D C   1 
ATOM   4984 O  O   . ALA D 1 118 ? 62.153  -18.187 40.872  1.00 69.49  ? 118 ALA D O   1 
ATOM   4985 C  CB  . ALA D 1 118 ? 59.603  -19.663 39.959  1.00 59.72  ? 118 ALA D CB  1 
ATOM   4986 N  N   . SER D 1 119 ? 60.800  -16.521 40.164  1.00 69.96  ? 119 SER D N   1 
ATOM   4987 C  CA  . SER D 1 119 ? 61.878  -15.569 39.916  1.00 67.52  ? 119 SER D CA  1 
ATOM   4988 C  C   . SER D 1 119 ? 62.363  -14.911 41.205  1.00 73.55  ? 119 SER D C   1 
ATOM   4989 O  O   . SER D 1 119 ? 63.573  -14.798 41.430  1.00 75.68  ? 119 SER D O   1 
ATOM   4990 C  CB  . SER D 1 119 ? 61.408  -14.501 38.932  1.00 58.86  ? 119 SER D CB  1 
ATOM   4991 O  OG  . SER D 1 119 ? 61.370  -15.023 37.623  1.00 62.20  ? 119 SER D OG  1 
ATOM   4992 N  N   . GLY D 1 120 ? 61.433  -14.461 42.054  1.00 74.17  ? 120 GLY D N   1 
ATOM   4993 C  CA  . GLY D 1 120 ? 61.774  -13.840 43.322  1.00 77.37  ? 120 GLY D CA  1 
ATOM   4994 C  C   . GLY D 1 120 ? 62.221  -14.820 44.390  1.00 77.80  ? 120 GLY D C   1 
ATOM   4995 O  O   . GLY D 1 120 ? 62.308  -14.465 45.568  1.00 84.55  ? 120 GLY D O   1 
ATOM   4996 N  N   . ASN D 1 121 ? 62.486  -16.065 43.991  1.00 74.60  ? 121 ASN D N   1 
ATOM   4997 C  CA  . ASN D 1 121 ? 63.026  -17.085 44.875  1.00 74.46  ? 121 ASN D CA  1 
ATOM   4998 C  C   . ASN D 1 121 ? 64.327  -17.663 44.350  1.00 75.62  ? 121 ASN D C   1 
ATOM   4999 O  O   . ASN D 1 121 ? 64.927  -18.511 45.021  1.00 76.63  ? 121 ASN D O   1 
ATOM   5000 C  CB  . ASN D 1 121 ? 62.019  -18.226 45.075  1.00 73.28  ? 121 ASN D CB  1 
ATOM   5001 C  CG  . ASN D 1 121 ? 60.815  -17.808 45.891  1.00 78.12  ? 121 ASN D CG  1 
ATOM   5002 O  OD1 . ASN D 1 121 ? 60.897  -16.918 46.740  1.00 74.98  ? 121 ASN D OD1 1 
ATOM   5003 N  ND2 . ASN D 1 121 ? 59.682  -18.450 45.634  1.00 81.10  ? 121 ASN D ND2 1 
ATOM   5004 N  N   . ASN D 1 122 ? 64.770  -17.234 43.169  1.00 75.49  ? 122 ASN D N   1 
ATOM   5005 C  CA  . ASN D 1 122 ? 65.964  -17.780 42.538  1.00 76.66  ? 122 ASN D CA  1 
ATOM   5006 C  C   . ASN D 1 122 ? 65.905  -19.299 42.534  1.00 82.03  ? 122 ASN D C   1 
ATOM   5007 O  O   . ASN D 1 122 ? 66.880  -19.991 42.837  1.00 84.14  ? 122 ASN D O   1 
ATOM   5008 C  CB  . ASN D 1 122 ? 67.224  -17.261 43.219  1.00 79.95  ? 122 ASN D CB  1 
ATOM   5009 C  CG  . ASN D 1 122 ? 67.144  -15.780 43.498  1.00 82.55  ? 122 ASN D CG  1 
ATOM   5010 O  OD1 . ASN D 1 122 ? 67.465  -14.960 42.633  1.00 78.60  ? 122 ASN D OD1 1 
ATOM   5011 N  ND2 . ASN D 1 122 ? 66.689  -15.422 44.701  1.00 74.62  ? 122 ASN D ND2 1 
ATOM   5012 N  N   . ASP D 1 123 ? 64.715  -19.811 42.257  1.00 82.08  ? 123 ASP D N   1 
ATOM   5013 C  CA  . ASP D 1 123 ? 64.528  -21.206 41.919  1.00 78.27  ? 123 ASP D CA  1 
ATOM   5014 C  C   . ASP D 1 123 ? 64.576  -21.262 40.404  1.00 72.56  ? 123 ASP D C   1 
ATOM   5015 O  O   . ASP D 1 123 ? 63.533  -21.184 39.749  1.00 75.03  ? 123 ASP D O   1 
ATOM   5016 C  CB  . ASP D 1 123 ? 63.204  -21.748 42.456  1.00 75.43  ? 123 ASP D CB  1 
ATOM   5017 C  CG  . ASP D 1 123 ? 63.095  -23.252 42.316  1.00 76.94  ? 123 ASP D CG  1 
ATOM   5018 O  OD1 . ASP D 1 123 ? 64.092  -23.888 41.897  1.00 73.64  ? 123 ASP D OD1 1 
ATOM   5019 O  OD2 . ASP D 1 123 ? 62.013  -23.793 42.627  1.00 77.68  ? 123 ASP D OD2 1 
ATOM   5020 N  N   . PRO D 1 124 ? 65.763  -21.352 39.808  1.00 71.93  ? 124 PRO D N   1 
ATOM   5021 C  CA  . PRO D 1 124 ? 65.830  -21.353 38.345  1.00 72.83  ? 124 PRO D CA  1 
ATOM   5022 C  C   . PRO D 1 124 ? 65.216  -22.595 37.735  1.00 72.12  ? 124 PRO D C   1 
ATOM   5023 O  O   . PRO D 1 124 ? 64.811  -22.559 36.563  1.00 68.62  ? 124 PRO D O   1 
ATOM   5024 C  CB  . PRO D 1 124 ? 67.336  -21.266 38.071  1.00 74.88  ? 124 PRO D CB  1 
ATOM   5025 C  CG  . PRO D 1 124 ? 67.954  -21.961 39.260  1.00 73.45  ? 124 PRO D CG  1 
ATOM   5026 C  CD  . PRO D 1 124 ? 67.068  -21.644 40.428  1.00 70.91  ? 124 PRO D CD  1 
ATOM   5027 N  N   . CYS D 1 125 ? 65.125  -23.683 38.510  1.00 72.83  ? 125 CYS D N   1 
ATOM   5028 C  CA  . CYS D 1 125 ? 64.561  -24.934 38.014  1.00 72.27  ? 125 CYS D CA  1 
ATOM   5029 C  C   . CYS D 1 125 ? 63.074  -24.795 37.734  1.00 70.89  ? 125 CYS D C   1 
ATOM   5030 O  O   . CYS D 1 125 ? 62.562  -25.339 36.749  1.00 68.36  ? 125 CYS D O   1 
ATOM   5031 C  CB  . CYS D 1 125 ? 64.782  -26.046 39.034  1.00 76.76  ? 125 CYS D CB  1 
ATOM   5032 S  SG  . CYS D 1 125 ? 66.465  -26.677 39.104  1.00 94.40  ? 125 CYS D SG  1 
ATOM   5033 N  N   . LEU D 1 126 ? 62.359  -24.107 38.622  1.00 67.23  ? 126 LEU D N   1 
ATOM   5034 C  CA  . LEU D 1 126 ? 60.936  -23.882 38.415  1.00 65.95  ? 126 LEU D CA  1 
ATOM   5035 C  C   . LEU D 1 126 ? 60.692  -23.006 37.187  1.00 69.68  ? 126 LEU D C   1 
ATOM   5036 O  O   . LEU D 1 126 ? 59.900  -23.365 36.304  1.00 67.97  ? 126 LEU D O   1 
ATOM   5037 C  CB  . LEU D 1 126 ? 60.331  -23.255 39.668  1.00 61.23  ? 126 LEU D CB  1 
ATOM   5038 C  CG  . LEU D 1 126 ? 58.820  -23.120 39.621  1.00 62.60  ? 126 LEU D CG  1 
ATOM   5039 C  CD1 . LEU D 1 126 ? 58.229  -24.373 39.011  1.00 65.36  ? 126 LEU D CD1 1 
ATOM   5040 C  CD2 . LEU D 1 126 ? 58.261  -22.890 41.006  1.00 64.87  ? 126 LEU D CD2 1 
ATOM   5041 N  N   . THR D 1 127 ? 61.364  -21.848 37.118  1.00 67.16  ? 127 THR D N   1 
ATOM   5042 C  CA  . THR D 1 127 ? 61.304  -21.003 35.924  1.00 67.33  ? 127 THR D CA  1 
ATOM   5043 C  C   . THR D 1 127 ? 61.687  -21.776 34.663  1.00 68.17  ? 127 THR D C   1 
ATOM   5044 O  O   . THR D 1 127 ? 61.106  -21.565 33.594  1.00 70.48  ? 127 THR D O   1 
ATOM   5045 C  CB  . THR D 1 127 ? 62.226  -19.791 36.084  1.00 64.46  ? 127 THR D CB  1 
ATOM   5046 O  OG1 . THR D 1 127 ? 63.593  -20.232 36.081  1.00 65.01  ? 127 THR D OG1 1 
ATOM   5047 C  CG2 . THR D 1 127 ? 61.925  -19.044 37.370  1.00 57.95  ? 127 THR D CG2 1 
ATOM   5048 N  N   . LYS D 1 128 ? 62.675  -22.667 34.765  1.00 66.44  ? 128 LYS D N   1 
ATOM   5049 C  CA  . LYS D 1 128 ? 63.069  -23.464 33.608  1.00 70.49  ? 128 LYS D CA  1 
ATOM   5050 C  C   . LYS D 1 128 ? 61.964  -24.438 33.196  1.00 74.51  ? 128 LYS D C   1 
ATOM   5051 O  O   . LYS D 1 128 ? 61.697  -24.603 31.999  1.00 72.78  ? 128 LYS D O   1 
ATOM   5052 C  CB  . LYS D 1 128 ? 64.356  -24.229 33.905  1.00 68.26  ? 128 LYS D CB  1 
ATOM   5053 C  CG  . LYS D 1 128 ? 65.051  -24.742 32.667  1.00 75.44  ? 128 LYS D CG  1 
ATOM   5054 C  CD  . LYS D 1 128 ? 65.842  -25.978 32.975  1.00 80.83  ? 128 LYS D CD  1 
ATOM   5055 C  CE  . LYS D 1 128 ? 66.108  -26.739 31.706  1.00 85.87  ? 128 LYS D CE  1 
ATOM   5056 N  NZ  . LYS D 1 128 ? 65.302  -27.989 31.744  1.00 88.33  ? 128 LYS D NZ  1 
ATOM   5057 N  N   . LEU D 1 129 ? 61.323  -25.101 34.169  1.00 68.38  ? 129 LEU D N   1 
ATOM   5058 C  CA  . LEU D 1 129 ? 60.225  -26.014 33.857  1.00 68.25  ? 129 LEU D CA  1 
ATOM   5059 C  C   . LEU D 1 129 ? 59.120  -25.296 33.096  1.00 71.95  ? 129 LEU D C   1 
ATOM   5060 O  O   . LEU D 1 129 ? 58.595  -25.814 32.104  1.00 71.64  ? 129 LEU D O   1 
ATOM   5061 C  CB  . LEU D 1 129 ? 59.657  -26.630 35.134  1.00 70.24  ? 129 LEU D CB  1 
ATOM   5062 C  CG  . LEU D 1 129 ? 58.290  -27.294 34.913  1.00 64.24  ? 129 LEU D CG  1 
ATOM   5063 C  CD1 . LEU D 1 129 ? 58.487  -28.663 34.293  1.00 65.09  ? 129 LEU D CD1 1 
ATOM   5064 C  CD2 . LEU D 1 129 ? 57.452  -27.370 36.180  1.00 62.34  ? 129 LEU D CD2 1 
ATOM   5065 N  N   . LEU D 1 130 ? 58.744  -24.100 33.557  1.00 68.73  ? 130 LEU D N   1 
ATOM   5066 C  CA  . LEU D 1 130 ? 57.767  -23.304 32.824  1.00 69.79  ? 130 LEU D CA  1 
ATOM   5067 C  C   . LEU D 1 130 ? 58.233  -23.065 31.389  1.00 72.85  ? 130 LEU D C   1 
ATOM   5068 O  O   . LEU D 1 130 ? 57.467  -23.249 30.436  1.00 71.44  ? 130 LEU D O   1 
ATOM   5069 C  CB  . LEU D 1 130 ? 57.511  -21.988 33.576  1.00 58.36  ? 130 LEU D CB  1 
ATOM   5070 C  CG  . LEU D 1 130 ? 57.214  -22.214 35.077  1.00 63.45  ? 130 LEU D CG  1 
ATOM   5071 C  CD1 . LEU D 1 130 ? 56.976  -20.949 35.883  1.00 54.13  ? 130 LEU D CD1 1 
ATOM   5072 C  CD2 . LEU D 1 130 ? 56.039  -23.142 35.263  1.00 62.90  ? 130 LEU D CD2 1 
ATOM   5073 N  N   . GLU D 1 131 ? 59.510  -22.738 31.211  1.00 72.94  ? 131 GLU D N   1 
ATOM   5074 C  CA  . GLU D 1 131 ? 60.009  -22.387 29.887  1.00 79.64  ? 131 GLU D CA  1 
ATOM   5075 C  C   . GLU D 1 131 ? 60.060  -23.593 28.950  1.00 86.28  ? 131 GLU D C   1 
ATOM   5076 O  O   . GLU D 1 131 ? 59.663  -23.490 27.782  1.00 89.69  ? 131 GLU D O   1 
ATOM   5077 C  CB  . GLU D 1 131 ? 61.384  -21.741 30.023  1.00 74.19  ? 131 GLU D CB  1 
ATOM   5078 C  CG  . GLU D 1 131 ? 61.287  -20.293 30.466  1.00 79.92  ? 131 GLU D CG  1 
ATOM   5079 C  CD  . GLU D 1 131 ? 62.531  -19.808 31.162  1.00 72.60  ? 131 GLU D CD  1 
ATOM   5080 O  OE1 . GLU D 1 131 ? 62.473  -18.707 31.751  1.00 71.41  ? 131 GLU D OE1 1 
ATOM   5081 O  OE2 . GLU D 1 131 ? 63.557  -20.526 31.109  1.00 74.26  ? 131 GLU D OE2 1 
ATOM   5082 N  N   . ASP D 1 132 ? 60.552  -24.740 29.433  1.00 83.58  ? 132 ASP D N   1 
ATOM   5083 C  CA  . ASP D 1 132 ? 60.700  -25.913 28.576  1.00 82.09  ? 132 ASP D CA  1 
ATOM   5084 C  C   . ASP D 1 132 ? 59.371  -26.560 28.212  1.00 87.16  ? 132 ASP D C   1 
ATOM   5085 O  O   . ASP D 1 132 ? 59.313  -27.287 27.213  1.00 87.82  ? 132 ASP D O   1 
ATOM   5086 C  CB  . ASP D 1 132 ? 61.579  -26.983 29.243  1.00 83.20  ? 132 ASP D CB  1 
ATOM   5087 C  CG  . ASP D 1 132 ? 62.860  -26.418 29.846  1.00 88.59  ? 132 ASP D CG  1 
ATOM   5088 O  OD1 . ASP D 1 132 ? 63.529  -25.572 29.203  1.00 86.01  ? 132 ASP D OD1 1 
ATOM   5089 O  OD2 . ASP D 1 132 ? 63.191  -26.831 30.981  1.00 88.71  ? 132 ASP D OD2 1 
ATOM   5090 N  N   . GLU D 1 133 ? 58.312  -26.330 28.994  1.00 86.04  ? 133 GLU D N   1 
ATOM   5091 C  CA  . GLU D 1 133 ? 57.072  -27.090 28.849  1.00 87.78  ? 133 GLU D CA  1 
ATOM   5092 C  C   . GLU D 1 133 ? 55.853  -26.235 28.535  1.00 86.07  ? 133 GLU D C   1 
ATOM   5093 O  O   . GLU D 1 133 ? 54.965  -26.687 27.806  1.00 81.57  ? 133 GLU D O   1 
ATOM   5094 C  CB  . GLU D 1 133 ? 56.787  -27.896 30.134  1.00 85.67  ? 133 GLU D CB  1 
ATOM   5095 C  CG  . GLU D 1 133 ? 57.947  -28.700 30.760  1.00 92.29  ? 133 GLU D CG  1 
ATOM   5096 C  CD  . GLU D 1 133 ? 58.553  -29.805 29.884  1.00 96.40  ? 133 GLU D CD  1 
ATOM   5097 O  OE1 . GLU D 1 133 ? 59.032  -30.799 30.469  1.00 96.08  ? 133 GLU D OE1 1 
ATOM   5098 O  OE2 . GLU D 1 133 ? 58.566  -29.703 28.637  1.00 101.28 ? 133 GLU D OE2 1 
ATOM   5099 N  N   . TYR D 1 134 ? 55.766  -25.017 29.074  1.00 83.94  ? 134 TYR D N   1 
ATOM   5100 C  CA  . TYR D 1 134 ? 54.555  -24.211 28.953  1.00 87.46  ? 134 TYR D CA  1 
ATOM   5101 C  C   . TYR D 1 134 ? 54.829  -22.910 28.220  1.00 88.72  ? 134 TYR D C   1 
ATOM   5102 O  O   . TYR D 1 134 ? 54.174  -21.886 28.458  1.00 87.57  ? 134 TYR D O   1 
ATOM   5103 C  CB  . TYR D 1 134 ? 53.933  -23.981 30.330  1.00 80.72  ? 134 TYR D CB  1 
ATOM   5104 C  CG  . TYR D 1 134 ? 53.552  -25.318 30.878  1.00 84.52  ? 134 TYR D CG  1 
ATOM   5105 C  CD1 . TYR D 1 134 ? 52.333  -25.902 30.544  1.00 87.79  ? 134 TYR D CD1 1 
ATOM   5106 C  CD2 . TYR D 1 134 ? 54.459  -26.061 31.625  1.00 84.80  ? 134 TYR D CD2 1 
ATOM   5107 C  CE1 . TYR D 1 134 ? 52.003  -27.166 30.996  1.00 81.75  ? 134 TYR D CE1 1 
ATOM   5108 C  CE2 . TYR D 1 134 ? 54.145  -27.326 32.075  1.00 85.84  ? 134 TYR D CE2 1 
ATOM   5109 C  CZ  . TYR D 1 134 ? 52.918  -27.874 31.758  1.00 81.35  ? 134 TYR D CZ  1 
ATOM   5110 O  OH  . TYR D 1 134 ? 52.610  -29.131 32.219  1.00 81.07  ? 134 TYR D OH  1 
ATOM   5111 N  N   . CYS D 1 135 ? 55.785  -22.947 27.328  1.00 82.18  ? 135 CYS D N   1 
ATOM   5112 C  CA  . CYS D 1 135 ? 55.909  -21.779 26.485  1.00 90.01  ? 135 CYS D CA  1 
ATOM   5113 C  C   . CYS D 1 135 ? 55.996  -22.089 25.006  1.00 90.82  ? 135 CYS D C   1 
ATOM   5114 O  O   . CYS D 1 135 ? 55.349  -21.399 24.217  1.00 94.06  ? 135 CYS D O   1 
ATOM   5115 C  CB  . CYS D 1 135 ? 57.089  -20.915 26.863  1.00 84.73  ? 135 CYS D CB  1 
ATOM   5116 S  SG  . CYS D 1 135 ? 56.642  -19.281 26.287  1.00 110.24 ? 135 CYS D SG  1 
ATOM   5117 N  N   . GLU D 1 136 ? 56.791  -23.079 24.602  1.00 90.43  ? 136 GLU D N   1 
ATOM   5118 C  CA  . GLU D 1 136 ? 56.976  -23.293 23.172  1.00 93.36  ? 136 GLU D CA  1 
ATOM   5119 C  C   . GLU D 1 136 ? 55.657  -23.658 22.508  1.00 94.57  ? 136 GLU D C   1 
ATOM   5120 O  O   . GLU D 1 136 ? 55.300  -23.104 21.462  1.00 92.68  ? 136 GLU D O   1 
ATOM   5121 C  CB  . GLU D 1 136 ? 58.029  -24.367 22.914  1.00 95.93  ? 136 GLU D CB  1 
ATOM   5122 C  CG  . GLU D 1 136 ? 58.653  -24.245 21.525  1.00 98.63  ? 136 GLU D CG  1 
ATOM   5123 C  CD  . GLU D 1 136 ? 59.415  -25.487 21.101  1.00 102.52 ? 136 GLU D CD  1 
ATOM   5124 O  OE1 . GLU D 1 136 ? 59.183  -25.973 19.969  1.00 100.22 ? 136 GLU D OE1 1 
ATOM   5125 O  OE2 . GLU D 1 136 ? 60.243  -25.977 21.900  1.00 104.01 ? 136 GLU D OE2 1 
ATOM   5126 N  N   . GLU D 1 137 ? 54.903  -24.566 23.114  1.00 90.73  ? 137 GLU D N   1 
ATOM   5127 C  CA  . GLU D 1 137 ? 53.633  -24.962 22.533  1.00 95.62  ? 137 GLU D CA  1 
ATOM   5128 C  C   . GLU D 1 137 ? 52.445  -24.226 23.137  1.00 90.60  ? 137 GLU D C   1 
ATOM   5129 O  O   . GLU D 1 137 ? 51.355  -24.280 22.558  1.00 90.90  ? 137 GLU D O   1 
ATOM   5130 C  CB  . GLU D 1 137 ? 53.433  -26.486 22.659  1.00 103.19 ? 137 GLU D CB  1 
ATOM   5131 C  CG  . GLU D 1 137 ? 52.642  -27.162 21.501  1.00 101.84 ? 137 GLU D CG  1 
ATOM   5132 C  CD  . GLU D 1 137 ? 51.154  -27.381 21.816  1.00 98.86  ? 137 GLU D CD  1 
ATOM   5133 O  OE1 . GLU D 1 137 ? 50.305  -27.189 20.910  1.00 91.89  ? 137 GLU D OE1 1 
ATOM   5134 O  OE2 . GLU D 1 137 ? 50.838  -27.750 22.974  1.00 101.64 ? 137 GLU D OE2 1 
ATOM   5135 N  N   . GLN D 1 138 ? 52.606  -23.531 24.270  1.00 86.68  ? 138 GLN D N   1 
ATOM   5136 C  CA  . GLN D 1 138 ? 51.447  -22.801 24.774  1.00 85.11  ? 138 GLN D CA  1 
ATOM   5137 C  C   . GLN D 1 138 ? 51.194  -21.552 23.946  1.00 81.81  ? 138 GLN D C   1 
ATOM   5138 O  O   . GLN D 1 138 ? 50.037  -21.173 23.733  1.00 77.08  ? 138 GLN D O   1 
ATOM   5139 C  CB  . GLN D 1 138 ? 51.598  -22.477 26.260  1.00 84.02  ? 138 GLN D CB  1 
ATOM   5140 C  CG  . GLN D 1 138 ? 50.653  -23.330 27.107  1.00 85.72  ? 138 GLN D CG  1 
ATOM   5141 C  CD  . GLN D 1 138 ? 50.615  -24.793 26.638  1.00 93.98  ? 138 GLN D CD  1 
ATOM   5142 O  OE1 . GLN D 1 138 ? 51.545  -25.571 26.884  1.00 93.64  ? 138 GLN D OE1 1 
ATOM   5143 N  NE2 . GLN D 1 138 ? 49.550  -25.156 25.926  1.00 90.81  ? 138 GLN D NE2 1 
ATOM   5144 N  N   . CYS D 1 139 ? 52.259  -20.936 23.433  1.00 86.51  ? 139 CYS D N   1 
ATOM   5145 C  CA  . CYS D 1 139 ? 52.107  -19.904 22.418  1.00 76.64  ? 139 CYS D CA  1 
ATOM   5146 C  C   . CYS D 1 139 ? 51.570  -20.481 21.109  1.00 77.28  ? 139 CYS D C   1 
ATOM   5147 O  O   . CYS D 1 139 ? 50.921  -19.761 20.342  1.00 77.05  ? 139 CYS D O   1 
ATOM   5148 C  CB  . CYS D 1 139 ? 53.448  -19.202 22.212  1.00 83.63  ? 139 CYS D CB  1 
ATOM   5149 S  SG  . CYS D 1 139 ? 53.711  -18.395 20.621  1.00 95.00  ? 139 CYS D SG  1 
ATOM   5150 N  N   . ASP D 1 140 ? 51.806  -21.774 20.847  1.00 81.72  ? 140 ASP D N   1 
ATOM   5151 C  CA  . ASP D 1 140 ? 51.190  -22.444 19.700  1.00 78.03  ? 140 ASP D CA  1 
ATOM   5152 C  C   . ASP D 1 140 ? 49.733  -22.839 19.959  1.00 73.05  ? 140 ASP D C   1 
ATOM   5153 O  O   . ASP D 1 140 ? 48.890  -22.701 19.063  1.00 69.86  ? 140 ASP D O   1 
ATOM   5154 C  CB  . ASP D 1 140 ? 51.997  -23.679 19.313  1.00 84.23  ? 140 ASP D CB  1 
ATOM   5155 C  CG  . ASP D 1 140 ? 53.223  -23.332 18.519  1.00 87.43  ? 140 ASP D CG  1 
ATOM   5156 O  OD1 . ASP D 1 140 ? 53.586  -22.131 18.516  1.00 83.83  ? 140 ASP D OD1 1 
ATOM   5157 O  OD2 . ASP D 1 140 ? 53.804  -24.251 17.895  1.00 81.50  ? 140 ASP D OD2 1 
ATOM   5158 N  N   . SER D 1 141 ? 49.428  -23.355 21.160  1.00 70.09  ? 141 SER D N   1 
ATOM   5159 C  CA  A SER D 1 141 ? 48.046  -23.703 21.493  0.68 70.99  ? 141 SER D CA  1 
ATOM   5160 C  CA  B SER D 1 141 ? 48.045  -23.701 21.494  0.32 69.93  ? 141 SER D CA  1 
ATOM   5161 C  C   . SER D 1 141 ? 47.143  -22.480 21.436  1.00 68.03  ? 141 SER D C   1 
ATOM   5162 O  O   . SER D 1 141 ? 46.014  -22.553 20.920  1.00 59.59  ? 141 SER D O   1 
ATOM   5163 C  CB  A SER D 1 141 ? 47.992  -24.354 22.877  0.68 74.03  ? 141 SER D CB  1 
ATOM   5164 C  CB  B SER D 1 141 ? 47.984  -24.348 22.880  0.32 72.77  ? 141 SER D CB  1 
ATOM   5165 O  OG  A SER D 1 141 ? 46.798  -25.097 23.045  0.68 69.92  ? 141 SER D OG  1 
ATOM   5166 O  OG  B SER D 1 141 ? 47.955  -25.763 22.791  0.32 75.52  ? 141 SER D OG  1 
ATOM   5167 N  N   . ILE D 1 142 ? 47.607  -21.336 21.956  1.00 67.91  ? 142 ILE D N   1 
ATOM   5168 C  CA  . ILE D 1 142 ? 46.834  -20.102 21.855  1.00 61.22  ? 142 ILE D CA  1 
ATOM   5169 C  C   . ILE D 1 142 ? 46.666  -19.702 20.392  1.00 58.23  ? 142 ILE D C   1 
ATOM   5170 O  O   . ILE D 1 142 ? 45.563  -19.356 19.946  1.00 49.61  ? 142 ILE D O   1 
ATOM   5171 C  CB  . ILE D 1 142 ? 47.480  -18.976 22.684  1.00 61.10  ? 142 ILE D CB  1 
ATOM   5172 C  CG1 . ILE D 1 142 ? 47.446  -19.322 24.170  1.00 66.92  ? 142 ILE D CG1 1 
ATOM   5173 C  CG2 . ILE D 1 142 ? 46.749  -17.649 22.474  1.00 56.89  ? 142 ILE D CG2 1 
ATOM   5174 C  CD1 . ILE D 1 142 ? 48.482  -18.587 24.992  1.00 68.17  ? 142 ILE D CD1 1 
ATOM   5175 N  N   . LYS D 1 143 ? 47.741  -19.776 19.608  1.00 60.38  ? 143 LYS D N   1 
ATOM   5176 C  CA  . LYS D 1 143 ? 47.619  -19.311 18.232  1.00 54.45  ? 143 LYS D CA  1 
ATOM   5177 C  C   . LYS D 1 143 ? 46.715  -20.211 17.404  1.00 52.75  ? 143 LYS D C   1 
ATOM   5178 O  O   . LYS D 1 143 ? 45.987  -19.705 16.542  1.00 53.50  ? 143 LYS D O   1 
ATOM   5179 C  CB  . LYS D 1 143 ? 48.978  -19.196 17.558  1.00 50.84  ? 143 LYS D CB  1 
ATOM   5180 C  CG  . LYS D 1 143 ? 48.903  -18.328 16.324  1.00 58.73  ? 143 LYS D CG  1 
ATOM   5181 C  CD  . LYS D 1 143 ? 49.492  -19.007 15.120  1.00 57.49  ? 143 LYS D CD  1 
ATOM   5182 C  CE  . LYS D 1 143 ? 49.856  -17.963 14.088  1.00 56.31  ? 143 LYS D CE  1 
ATOM   5183 N  NZ  . LYS D 1 143 ? 50.020  -18.557 12.755  1.00 51.33  ? 143 LYS D NZ  1 
ATOM   5184 N  N   . LYS D 1 144 ? 46.736  -21.531 17.636  1.00 50.10  ? 144 LYS D N   1 
ATOM   5185 C  CA  . LYS D 1 144 ? 45.909  -22.410 16.814  1.00 49.85  ? 144 LYS D CA  1 
ATOM   5186 C  C   . LYS D 1 144 ? 44.427  -22.155 17.067  1.00 48.91  ? 144 LYS D C   1 
ATOM   5187 O  O   . LYS D 1 144 ? 43.617  -22.205 16.128  1.00 46.63  ? 144 LYS D O   1 
ATOM   5188 C  CB  . LYS D 1 144 ? 46.272  -23.888 17.039  1.00 52.76  ? 144 LYS D CB  1 
ATOM   5189 C  CG  . LYS D 1 144 ? 45.823  -24.493 18.373  1.00 71.80  ? 144 LYS D CG  1 
ATOM   5190 C  CD  . LYS D 1 144 ? 45.564  -26.034 18.334  1.00 67.52  ? 144 LYS D CD  1 
ATOM   5191 C  CE  . LYS D 1 144 ? 45.626  -26.672 19.768  1.00 70.52  ? 144 LYS D CE  1 
ATOM   5192 N  NZ  . LYS D 1 144 ? 44.783  -25.991 20.817  1.00 60.71  ? 144 LYS D NZ  1 
ATOM   5193 N  N   . ILE D 1 145 ? 44.059  -21.838 18.320  1.00 43.08  ? 145 ILE D N   1 
ATOM   5194 C  CA  . ILE D 1 145 ? 42.668  -21.514 18.623  1.00 37.27  ? 145 ILE D CA  1 
ATOM   5195 C  C   . ILE D 1 145 ? 42.293  -20.189 17.985  1.00 39.50  ? 145 ILE D C   1 
ATOM   5196 O  O   . ILE D 1 145 ? 41.281  -20.089 17.275  1.00 36.78  ? 145 ILE D O   1 
ATOM   5197 C  CB  . ILE D 1 145 ? 42.412  -21.495 20.143  1.00 40.64  ? 145 ILE D CB  1 
ATOM   5198 C  CG1 . ILE D 1 145 ? 42.634  -22.878 20.767  1.00 44.74  ? 145 ILE D CG1 1 
ATOM   5199 C  CG2 . ILE D 1 145 ? 40.987  -21.047 20.429  1.00 32.76  ? 145 ILE D CG2 1 
ATOM   5200 C  CD1 . ILE D 1 145 ? 42.288  -22.952 22.252  1.00 40.63  ? 145 ILE D CD1 1 
ATOM   5201 N  N   . GLY D 1 146 ? 43.115  -19.154 18.218  1.00 38.24  ? 146 GLY D N   1 
ATOM   5202 C  CA  . GLY D 1 146 ? 42.881  -17.877 17.566  1.00 38.32  ? 146 GLY D CA  1 
ATOM   5203 C  C   . GLY D 1 146 ? 42.714  -18.036 16.074  1.00 37.26  ? 146 GLY D C   1 
ATOM   5204 O  O   . GLY D 1 146 ? 41.858  -17.404 15.453  1.00 39.20  ? 146 GLY D O   1 
ATOM   5205 N  N   . CYS D 1 147 ? 43.469  -18.951 15.498  1.00 39.22  ? 147 CYS D N   1 
ATOM   5206 C  CA  . CYS D 1 147 ? 43.436  -19.146 14.068  1.00 38.59  ? 147 CYS D CA  1 
ATOM   5207 C  C   . CYS D 1 147 ? 42.202  -19.958 13.678  1.00 41.40  ? 147 CYS D C   1 
ATOM   5208 O  O   . CYS D 1 147 ? 41.590  -19.700 12.633  1.00 37.61  ? 147 CYS D O   1 
ATOM   5209 C  CB  . CYS D 1 147 ? 44.756  -19.804 13.664  1.00 43.24  ? 147 CYS D CB  1 
ATOM   5210 S  SG  . CYS D 1 147 ? 45.311  -19.522 12.022  1.00 68.49  ? 147 CYS D SG  1 
ATOM   5211 N  N   . MET D 1 148 ? 41.765  -20.891 14.535  1.00 35.36  ? 148 MET D N   1 
ATOM   5212 C  CA  . MET D 1 148 ? 40.485  -21.542 14.279  1.00 35.32  ? 148 MET D CA  1 
ATOM   5213 C  C   . MET D 1 148 ? 39.343  -20.526 14.313  1.00 39.77  ? 148 MET D C   1 
ATOM   5214 O  O   . MET D 1 148 ? 38.478  -20.514 13.425  1.00 37.13  ? 148 MET D O   1 
ATOM   5215 C  CB  . MET D 1 148 ? 40.250  -22.664 15.287  1.00 42.21  ? 148 MET D CB  1 
ATOM   5216 C  CG  . MET D 1 148 ? 41.177  -23.833 15.110  1.00 37.27  ? 148 MET D CG  1 
ATOM   5217 S  SD  . MET D 1 148 ? 41.178  -24.854 16.588  1.00 44.50  ? 148 MET D SD  1 
ATOM   5218 C  CE  . MET D 1 148 ? 39.535  -25.563 16.450  1.00 44.26  ? 148 MET D CE  1 
ATOM   5219 N  N   . ILE D 1 149 ? 39.325  -19.661 15.338  1.00 38.02  ? 149 ILE D N   1 
ATOM   5220 C  CA  . ILE D 1 149 ? 38.325  -18.594 15.402  1.00 38.63  ? 149 ILE D CA  1 
ATOM   5221 C  C   . ILE D 1 149 ? 38.292  -17.816 14.091  1.00 42.05  ? 149 ILE D C   1 
ATOM   5222 O  O   . ILE D 1 149 ? 37.227  -17.613 13.489  1.00 38.29  ? 149 ILE D O   1 
ATOM   5223 C  CB  . ILE D 1 149 ? 38.619  -17.662 16.588  1.00 36.76  ? 149 ILE D CB  1 
ATOM   5224 C  CG1 . ILE D 1 149 ? 38.373  -18.397 17.909  1.00 37.57  ? 149 ILE D CG1 1 
ATOM   5225 C  CG2 . ILE D 1 149 ? 37.770  -16.420 16.492  1.00 32.03  ? 149 ILE D CG2 1 
ATOM   5226 C  CD1 . ILE D 1 149 ? 38.972  -17.709 19.102  1.00 36.21  ? 149 ILE D CD1 1 
ATOM   5227 N  N   . THR D 1 150 ? 39.470  -17.379 13.628  1.00 39.48  ? 150 THR D N   1 
ATOM   5228 C  CA  . THR D 1 150 ? 39.550  -16.589 12.405  1.00 40.07  ? 150 THR D CA  1 
ATOM   5229 C  C   . THR D 1 150 ? 38.961  -17.343 11.229  1.00 39.61  ? 150 THR D C   1 
ATOM   5230 O  O   . THR D 1 150 ? 38.181  -16.790 10.450  1.00 40.04  ? 150 THR D O   1 
ATOM   5231 C  CB  . THR D 1 150 ? 40.998  -16.215 12.111  1.00 39.67  ? 150 THR D CB  1 
ATOM   5232 O  OG1 . THR D 1 150 ? 41.504  -15.398 13.177  1.00 37.07  ? 150 THR D OG1 1 
ATOM   5233 C  CG2 . THR D 1 150 ? 41.093  -15.474 10.760  1.00 28.97  ? 150 THR D CG2 1 
ATOM   5234 N  N   . LYS D 1 151 ? 39.326  -18.615 11.089  1.00 41.62  ? 151 LYS D N   1 
ATOM   5235 C  CA  . LYS D 1 151 ? 38.825  -19.414 9.979   1.00 40.35  ? 151 LYS D CA  1 
ATOM   5236 C  C   . LYS D 1 151 ? 37.320  -19.593 10.080  1.00 44.21  ? 151 LYS D C   1 
ATOM   5237 O  O   . LYS D 1 151 ? 36.597  -19.443 9.089   1.00 45.14  ? 151 LYS D O   1 
ATOM   5238 C  CB  . LYS D 1 151 ? 39.531  -20.771 9.951   1.00 41.09  ? 151 LYS D CB  1 
ATOM   5239 C  CG  . LYS D 1 151 ? 39.133  -21.624 8.770   1.00 50.37  ? 151 LYS D CG  1 
ATOM   5240 C  CD  . LYS D 1 151 ? 39.741  -23.026 8.836   1.00 48.08  ? 151 LYS D CD  1 
ATOM   5241 C  CE  . LYS D 1 151 ? 39.358  -23.852 7.601   1.00 47.50  ? 151 LYS D CE  1 
ATOM   5242 N  NZ  . LYS D 1 151 ? 39.890  -25.236 7.646   1.00 48.32  ? 151 LYS D NZ  1 
ATOM   5243 N  N   . LEU D 1 152 ? 36.826  -19.916 11.277  1.00 43.09  ? 152 LEU D N   1 
ATOM   5244 C  CA  . LEU D 1 152 ? 35.390  -20.093 11.442  1.00 41.02  ? 152 LEU D CA  1 
ATOM   5245 C  C   . LEU D 1 152 ? 34.649  -18.807 11.118  1.00 40.82  ? 152 LEU D C   1 
ATOM   5246 O  O   . LEU D 1 152 ? 33.578  -18.840 10.507  1.00 40.73  ? 152 LEU D O   1 
ATOM   5247 C  CB  . LEU D 1 152 ? 35.082  -20.567 12.863  1.00 43.87  ? 152 LEU D CB  1 
ATOM   5248 C  CG  . LEU D 1 152 ? 33.693  -21.126 13.165  1.00 44.01  ? 152 LEU D CG  1 
ATOM   5249 C  CD1 . LEU D 1 152 ? 33.270  -22.143 12.128  1.00 43.99  ? 152 LEU D CD1 1 
ATOM   5250 C  CD2 . LEU D 1 152 ? 33.701  -21.778 14.539  1.00 43.02  ? 152 LEU D CD2 1 
ATOM   5251 N  N   . LYS D 1 153 ? 35.218  -17.657 11.483  1.00 37.87  ? 153 LYS D N   1 
ATOM   5252 C  CA  . LYS D 1 153 ? 34.585  -16.395 11.092  1.00 46.27  ? 153 LYS D CA  1 
ATOM   5253 C  C   . LYS D 1 153 ? 34.518  -16.235 9.569   1.00 44.07  ? 153 LYS D C   1 
ATOM   5254 O  O   . LYS D 1 153 ? 33.496  -15.790 9.035   1.00 44.76  ? 153 LYS D O   1 
ATOM   5255 C  CB  . LYS D 1 153 ? 35.315  -15.206 11.724  1.00 33.51  ? 153 LYS D CB  1 
ATOM   5256 C  CG  . LYS D 1 153 ? 34.938  -14.976 13.182  1.00 39.14  ? 153 LYS D CG  1 
ATOM   5257 C  CD  . LYS D 1 153 ? 35.564  -13.712 13.727  1.00 39.61  ? 153 LYS D CD  1 
ATOM   5258 C  CE  . LYS D 1 153 ? 35.161  -13.485 15.188  1.00 50.75  ? 153 LYS D CE  1 
ATOM   5259 N  NZ  . LYS D 1 153 ? 35.993  -12.413 15.853  1.00 57.83  ? 153 LYS D NZ  1 
ATOM   5260 N  N   . ARG D 1 154 ? 35.593  -16.588 8.852   1.00 40.75  ? 154 ARG D N   1 
ATOM   5261 C  CA  . ARG D 1 154 ? 35.640  -16.342 7.409   1.00 44.67  ? 154 ARG D CA  1 
ATOM   5262 C  C   . ARG D 1 154 ? 34.677  -17.259 6.666   1.00 45.62  ? 154 ARG D C   1 
ATOM   5263 O  O   . ARG D 1 154 ? 33.837  -16.797 5.887   1.00 43.79  ? 154 ARG D O   1 
ATOM   5264 C  CB  . ARG D 1 154 ? 37.065  -16.528 6.869   1.00 44.98  ? 154 ARG D CB  1 
ATOM   5265 C  CG  . ARG D 1 154 ? 37.097  -16.845 5.356   1.00 45.47  ? 154 ARG D CG  1 
ATOM   5266 C  CD  . ARG D 1 154 ? 38.508  -17.075 4.812   1.00 43.93  ? 154 ARG D CD  1 
ATOM   5267 N  NE  . ARG D 1 154 ? 39.335  -15.906 5.081   1.00 44.57  ? 154 ARG D NE  1 
ATOM   5268 C  CZ  . ARG D 1 154 ? 40.312  -15.894 5.971   1.00 43.29  ? 154 ARG D CZ  1 
ATOM   5269 N  NH1 . ARG D 1 154 ? 40.609  -17.014 6.646   1.00 46.62  ? 154 ARG D NH1 1 
ATOM   5270 N  NH2 . ARG D 1 154 ? 40.988  -14.778 6.179   1.00 36.39  ? 154 ARG D NH2 1 
ATOM   5271 N  N   . CYS D 1 155 ? 34.775  -18.567 6.912   1.00 38.49  ? 155 CYS D N   1 
ATOM   5272 C  CA  . CYS D 1 155 ? 33.923  -19.569 6.282   1.00 45.36  ? 155 CYS D CA  1 
ATOM   5273 C  C   . CYS D 1 155 ? 32.446  -19.279 6.525   1.00 52.55  ? 155 CYS D C   1 
ATOM   5274 O  O   . CYS D 1 155 ? 31.579  -19.978 5.994   1.00 53.48  ? 155 CYS D O   1 
ATOM   5275 C  CB  . CYS D 1 155 ? 34.281  -20.974 6.800   1.00 41.54  ? 155 CYS D CB  1 
ATOM   5276 S  SG  . CYS D 1 155 ? 35.945  -21.563 6.302   1.00 70.65  ? 155 CYS D SG  1 
ATOM   5277 N  N   . GLY D 1 156 ? 32.148  -18.217 7.274   1.00 57.20  ? 156 GLY D N   1 
ATOM   5278 C  CA  . GLY D 1 156 ? 30.838  -18.003 7.829   1.00 50.85  ? 156 GLY D CA  1 
ATOM   5279 C  C   . GLY D 1 156 ? 30.791  -18.853 9.071   1.00 56.22  ? 156 GLY D C   1 
ATOM   5280 O  O   . GLY D 1 156 ? 31.113  -20.051 9.027   1.00 55.25  ? 156 GLY D O   1 
ATOM   5281 N  N   . PRO D 1 157 ? 30.467  -18.241 10.219  1.00 49.26  ? 157 PRO D N   1 
ATOM   5282 C  CA  . PRO D 1 157 ? 30.508  -18.977 11.497  1.00 51.70  ? 157 PRO D CA  1 
ATOM   5283 C  C   . PRO D 1 157 ? 29.330  -19.916 11.714  1.00 53.06  ? 157 PRO D C   1 
ATOM   5284 O  O   . PRO D 1 157 ? 29.368  -20.715 12.662  1.00 61.30  ? 157 PRO D O   1 
ATOM   5285 C  CB  . PRO D 1 157 ? 30.508  -17.858 12.560  1.00 47.66  ? 157 PRO D CB  1 
ATOM   5286 C  CG  . PRO D 1 157 ? 30.343  -16.541 11.797  1.00 43.88  ? 157 PRO D CG  1 
ATOM   5287 C  CD  . PRO D 1 157 ? 29.970  -16.868 10.381  1.00 50.52  ? 157 PRO D CD  1 
ATOM   5288 N  N   . THR D 1 158 ? 28.293  -19.835 10.878  1.00 55.59  ? 158 THR D N   1 
ATOM   5289 C  CA  . THR D 1 158 ? 27.078  -20.624 11.012  1.00 56.11  ? 158 THR D CA  1 
ATOM   5290 C  C   . THR D 1 158 ? 26.780  -21.362 9.713   1.00 55.50  ? 158 THR D C   1 
ATOM   5291 O  O   . THR D 1 158 ? 27.307  -21.031 8.646   1.00 53.26  ? 158 THR D O   1 
ATOM   5292 C  CB  . THR D 1 158 ? 25.878  -19.740 11.375  1.00 59.02  ? 158 THR D CB  1 
ATOM   5293 O  OG1 . THR D 1 158 ? 25.864  -18.604 10.503  1.00 67.71  ? 158 THR D OG1 1 
ATOM   5294 C  CG2 . THR D 1 158 ? 25.962  -19.276 12.833  1.00 47.78  ? 158 THR D CG2 1 
ATOM   5295 N  N   . GLY D 1 159 ? 25.927  -22.378 9.827   1.00 58.87  ? 159 GLY D N   1 
ATOM   5296 C  CA  . GLY D 1 159 ? 25.433  -23.069 8.644   1.00 44.71  ? 159 GLY D CA  1 
ATOM   5297 C  C   . GLY D 1 159 ? 26.517  -23.837 7.922   1.00 41.92  ? 159 GLY D C   1 
ATOM   5298 O  O   . GLY D 1 159 ? 27.331  -24.536 8.533   1.00 48.75  ? 159 GLY D O   1 
ATOM   5299 N  N   . LEU D 1 160 ? 26.537  -23.687 6.597   1.00 46.94  ? 160 LEU D N   1 
ATOM   5300 C  CA  . LEU D 1 160 ? 27.418  -24.488 5.753   1.00 40.27  ? 160 LEU D CA  1 
ATOM   5301 C  C   . LEU D 1 160 ? 28.883  -24.297 6.128   1.00 45.38  ? 160 LEU D C   1 
ATOM   5302 O  O   . LEU D 1 160 ? 29.643  -25.269 6.202   1.00 49.43  ? 160 LEU D O   1 
ATOM   5303 C  CB  . LEU D 1 160 ? 27.189  -24.131 4.284   1.00 35.46  ? 160 LEU D CB  1 
ATOM   5304 C  CG  . LEU D 1 160 ? 28.045  -24.934 3.312   1.00 44.92  ? 160 LEU D CG  1 
ATOM   5305 C  CD1 . LEU D 1 160 ? 27.703  -26.406 3.481   1.00 56.57  ? 160 LEU D CD1 1 
ATOM   5306 C  CD2 . LEU D 1 160 ? 27.754  -24.522 1.907   1.00 48.91  ? 160 LEU D CD2 1 
ATOM   5307 N  N   . GLY D 1 161 ? 29.302  -23.058 6.382   1.00 45.65  ? 161 GLY D N   1 
ATOM   5308 C  CA  . GLY D 1 161 ? 30.695  -22.833 6.741   1.00 44.27  ? 161 GLY D CA  1 
ATOM   5309 C  C   . GLY D 1 161 ? 31.084  -23.507 8.044   1.00 42.49  ? 161 GLY D C   1 
ATOM   5310 O  O   . GLY D 1 161 ? 32.212  -23.975 8.196   1.00 45.34  ? 161 GLY D O   1 
ATOM   5311 N  N   . GLU D 1 162 ? 30.159  -23.567 9.001   1.00 45.55  ? 162 GLU D N   1 
ATOM   5312 C  CA  . GLU D 1 162 ? 30.423  -24.317 10.226  1.00 46.98  ? 162 GLU D CA  1 
ATOM   5313 C  C   . GLU D 1 162 ? 30.683  -25.786 9.911   1.00 44.60  ? 162 GLU D C   1 
ATOM   5314 O  O   . GLU D 1 162 ? 31.674  -26.360 10.376  1.00 42.67  ? 162 GLU D O   1 
ATOM   5315 C  CB  . GLU D 1 162 ? 29.254  -24.154 11.199  1.00 45.51  ? 162 GLU D CB  1 
ATOM   5316 C  CG  . GLU D 1 162 ? 29.596  -24.407 12.667  1.00 51.23  ? 162 GLU D CG  1 
ATOM   5317 C  CD  . GLU D 1 162 ? 28.377  -24.382 13.601  1.00 52.95  ? 162 GLU D CD  1 
ATOM   5318 O  OE1 . GLU D 1 162 ? 27.215  -24.317 13.122  1.00 58.01  ? 162 GLU D OE1 1 
ATOM   5319 O  OE2 . GLU D 1 162 ? 28.587  -24.434 14.829  1.00 54.39  ? 162 GLU D OE2 1 
ATOM   5320 N  N   . CYS D 1 163 ? 29.809  -26.400 9.096   1.00 49.72  ? 163 CYS D N   1 
ATOM   5321 C  CA  . CYS D 1 163 ? 29.993  -27.778 8.619   1.00 48.99  ? 163 CYS D CA  1 
ATOM   5322 C  C   . CYS D 1 163 ? 31.365  -27.999 8.007   1.00 52.15  ? 163 CYS D C   1 
ATOM   5323 O  O   . CYS D 1 163 ? 32.046  -28.984 8.309   1.00 50.26  ? 163 CYS D O   1 
ATOM   5324 C  CB  . CYS D 1 163 ? 28.954  -28.121 7.556   1.00 52.51  ? 163 CYS D CB  1 
ATOM   5325 S  SG  . CYS D 1 163 ? 27.324  -28.490 8.155   1.00 69.11  ? 163 CYS D SG  1 
ATOM   5326 N  N   . MET D 1 164 ? 31.761  -27.122 7.085   1.00 47.95  ? 164 MET D N   1 
ATOM   5327 C  CA  . MET D 1 164 ? 33.017  -27.340 6.385   1.00 51.71  ? 164 MET D CA  1 
ATOM   5328 C  C   . MET D 1 164 ? 34.208  -27.093 7.293   1.00 56.20  ? 164 MET D C   1 
ATOM   5329 O  O   . MET D 1 164 ? 35.237  -27.777 7.172   1.00 53.91  ? 164 MET D O   1 
ATOM   5330 C  CB  . MET D 1 164 ? 33.085  -26.456 5.143   1.00 51.15  ? 164 MET D CB  1 
ATOM   5331 C  CG  . MET D 1 164 ? 33.289  -27.245 3.842   1.00 70.55  ? 164 MET D CG  1 
ATOM   5332 S  SD  . MET D 1 164 ? 32.263  -28.714 3.531   1.00 86.98  ? 164 MET D SD  1 
ATOM   5333 C  CE  . MET D 1 164 ? 30.641  -27.997 3.461   1.00 61.39  ? 164 MET D CE  1 
ATOM   5334 N  N   . PHE D 1 165 ? 34.084  -26.136 8.215   1.00 46.28  ? 165 PHE D N   1 
ATOM   5335 C  CA  . PHE D 1 165 ? 35.095  -25.992 9.254   1.00 46.18  ? 165 PHE D CA  1 
ATOM   5336 C  C   . PHE D 1 165 ? 35.256  -27.289 10.041  1.00 44.85  ? 165 PHE D C   1 
ATOM   5337 O  O   . PHE D 1 165 ? 36.368  -27.794 10.211  1.00 49.22  ? 165 PHE D O   1 
ATOM   5338 C  CB  . PHE D 1 165 ? 34.730  -24.839 10.187  1.00 45.93  ? 165 PHE D CB  1 
ATOM   5339 C  CG  . PHE D 1 165 ? 35.738  -24.605 11.260  1.00 46.48  ? 165 PHE D CG  1 
ATOM   5340 C  CD1 . PHE D 1 165 ? 36.871  -23.846 11.006  1.00 45.10  ? 165 PHE D CD1 1 
ATOM   5341 C  CD2 . PHE D 1 165 ? 35.578  -25.173 12.512  1.00 41.45  ? 165 PHE D CD2 1 
ATOM   5342 C  CE1 . PHE D 1 165 ? 37.807  -23.628 11.991  1.00 40.61  ? 165 PHE D CE1 1 
ATOM   5343 C  CE2 . PHE D 1 165 ? 36.521  -24.969 13.492  1.00 44.92  ? 165 PHE D CE2 1 
ATOM   5344 C  CZ  . PHE D 1 165 ? 37.641  -24.187 13.227  1.00 41.83  ? 165 PHE D CZ  1 
ATOM   5345 N  N   . ASP D 1 166 ? 34.148  -27.845 10.528  1.00 45.56  ? 166 ASP D N   1 
ATOM   5346 C  CA  . ASP D 1 166 ? 34.221  -29.065 11.325  1.00 49.44  ? 166 ASP D CA  1 
ATOM   5347 C  C   . ASP D 1 166 ? 34.859  -30.210 10.546  1.00 50.56  ? 166 ASP D C   1 
ATOM   5348 O  O   . ASP D 1 166 ? 35.668  -30.969 11.099  1.00 52.86  ? 166 ASP D O   1 
ATOM   5349 C  CB  . ASP D 1 166 ? 32.828  -29.468 11.799  1.00 47.51  ? 166 ASP D CB  1 
ATOM   5350 C  CG  . ASP D 1 166 ? 32.864  -30.677 12.688  1.00 45.19  ? 166 ASP D CG  1 
ATOM   5351 O  OD1 . ASP D 1 166 ? 32.964  -30.482 13.911  1.00 45.21  ? 166 ASP D OD1 1 
ATOM   5352 O  OD2 . ASP D 1 166 ? 32.833  -31.818 12.167  1.00 47.71  ? 166 ASP D OD2 1 
ATOM   5353 N  N   . LYS D 1 167 ? 34.495  -30.356 9.265   1.00 51.64  ? 167 LYS D N   1 
ATOM   5354 C  CA  . LYS D 1 167 ? 35.117  -31.361 8.398   1.00 54.44  ? 167 LYS D CA  1 
ATOM   5355 C  C   . LYS D 1 167 ? 36.629  -31.199 8.333   1.00 53.33  ? 167 LYS D C   1 
ATOM   5356 O  O   . LYS D 1 167 ? 37.376  -32.163 8.534   1.00 57.18  ? 167 LYS D O   1 
ATOM   5357 C  CB  . LYS D 1 167 ? 34.534  -31.284 6.987   1.00 58.97  ? 167 LYS D CB  1 
ATOM   5358 C  CG  . LYS D 1 167 ? 34.724  -32.570 6.193   1.00 62.63  ? 167 LYS D CG  1 
ATOM   5359 C  CD  . LYS D 1 167 ? 35.374  -32.286 4.852   1.00 71.16  ? 167 LYS D CD  1 
ATOM   5360 C  CE  . LYS D 1 167 ? 35.084  -33.387 3.839   1.00 75.19  ? 167 LYS D CE  1 
ATOM   5361 N  NZ  . LYS D 1 167 ? 35.316  -32.906 2.441   1.00 71.52  ? 167 LYS D NZ  1 
ATOM   5362 N  N   . GLU D 1 168 ? 37.100  -29.985 8.029   1.00 50.49  ? 168 GLU D N   1 
ATOM   5363 C  CA  . GLU D 1 168 ? 38.533  -29.757 7.900   1.00 47.59  ? 168 GLU D CA  1 
ATOM   5364 C  C   . GLU D 1 168 ? 39.247  -29.886 9.235   1.00 57.18  ? 168 GLU D C   1 
ATOM   5365 O  O   . GLU D 1 168 ? 40.481  -29.967 9.267   1.00 49.42  ? 168 GLU D O   1 
ATOM   5366 C  CB  . GLU D 1 168 ? 38.779  -28.383 7.283   1.00 46.05  ? 168 GLU D CB  1 
ATOM   5367 C  CG  . GLU D 1 168 ? 38.584  -28.334 5.761   1.00 59.72  ? 168 GLU D CG  1 
ATOM   5368 C  CD  . GLU D 1 168 ? 38.745  -26.916 5.165   1.00 74.19  ? 168 GLU D CD  1 
ATOM   5369 O  OE1 . GLU D 1 168 ? 37.889  -26.506 4.341   1.00 77.35  ? 168 GLU D OE1 1 
ATOM   5370 O  OE2 . GLU D 1 168 ? 39.724  -26.210 5.515   1.00 71.66  ? 168 GLU D OE2 1 
ATOM   5371 N  N   . LEU D 1 169 ? 38.496  -29.906 10.335  1.00 58.87  ? 169 LEU D N   1 
ATOM   5372 C  CA  . LEU D 1 169 ? 39.090  -30.111 11.646  1.00 58.67  ? 169 LEU D CA  1 
ATOM   5373 C  C   . LEU D 1 169 ? 39.346  -31.590 11.885  1.00 66.28  ? 169 LEU D C   1 
ATOM   5374 O  O   . LEU D 1 169 ? 40.461  -31.989 12.253  1.00 62.22  ? 169 LEU D O   1 
ATOM   5375 C  CB  . LEU D 1 169 ? 38.164  -29.540 12.713  1.00 48.51  ? 169 LEU D CB  1 
ATOM   5376 C  CG  . LEU D 1 169 ? 38.740  -29.364 14.105  1.00 55.22  ? 169 LEU D CG  1 
ATOM   5377 C  CD1 . LEU D 1 169 ? 39.915  -28.418 14.063  1.00 47.82  ? 169 LEU D CD1 1 
ATOM   5378 C  CD2 . LEU D 1 169 ? 37.646  -28.799 14.998  1.00 54.12  ? 169 LEU D CD2 1 
ATOM   5379 N  N   . ASN D 1 170 ? 38.321  -32.406 11.621  1.00 67.05  ? 170 ASN D N   1 
ATOM   5380 C  CA  . ASN D 1 170 ? 38.250  -33.839 11.924  1.00 69.34  ? 170 ASN D CA  1 
ATOM   5381 C  C   . ASN D 1 170 ? 39.531  -34.641 11.645  1.00 79.49  ? 170 ASN D C   1 
ATOM   5382 O  O   . ASN D 1 170 ? 40.416  -34.244 10.861  1.00 76.30  ? 170 ASN D O   1 
ATOM   5383 C  CB  . ASN D 1 170 ? 37.086  -34.454 11.128  1.00 64.87  ? 170 ASN D CB  1 
ATOM   5384 C  CG  . ASN D 1 170 ? 36.150  -35.305 11.995  1.00 73.98  ? 170 ASN D CG  1 
ATOM   5385 O  OD1 . ASN D 1 170 ? 36.587  -36.073 12.870  1.00 72.89  ? 170 ASN D OD1 1 
ATOM   5386 N  ND2 . ASN D 1 170 ? 34.847  -35.177 11.741  1.00 71.51  ? 170 ASN D ND2 1 
ATOM   5387 O  OXT . ASN D 1 170 ? 39.680  -35.733 12.212  1.00 74.67  ? 170 ASN D OXT 1 
ATOM   5388 N  N   . ALA E 1 2   ? 11.376  -32.121 24.078  1.00 96.84  ? 2   ALA E N   1 
ATOM   5389 C  CA  . ALA E 1 2   ? 12.565  -32.898 24.410  1.00 98.90  ? 2   ALA E CA  1 
ATOM   5390 C  C   . ALA E 1 2   ? 13.552  -32.923 23.241  1.00 97.32  ? 2   ALA E C   1 
ATOM   5391 O  O   . ALA E 1 2   ? 13.696  -31.938 22.510  1.00 93.19  ? 2   ALA E O   1 
ATOM   5392 C  CB  . ALA E 1 2   ? 12.176  -34.328 24.815  1.00 92.09  ? 2   ALA E CB  1 
ATOM   5393 N  N   . SER E 1 3   ? 14.235  -34.058 23.090  1.00 96.83  ? 3   SER E N   1 
ATOM   5394 C  CA  . SER E 1 3   ? 15.174  -34.313 22.007  1.00 88.46  ? 3   SER E CA  1 
ATOM   5395 C  C   . SER E 1 3   ? 14.585  -35.366 21.071  1.00 88.77  ? 3   SER E C   1 
ATOM   5396 O  O   . SER E 1 3   ? 13.858  -36.266 21.504  1.00 87.78  ? 3   SER E O   1 
ATOM   5397 C  CB  . SER E 1 3   ? 16.534  -34.763 22.567  1.00 78.75  ? 3   SER E CB  1 
ATOM   5398 O  OG  . SER E 1 3   ? 17.202  -35.684 21.716  1.00 73.73  ? 3   SER E OG  1 
ATOM   5399 N  N   . GLN E 1 4   ? 14.892  -35.242 19.773  1.00 83.79  ? 4   GLN E N   1 
ATOM   5400 C  CA  . GLN E 1 4   ? 14.208  -36.058 18.772  1.00 85.73  ? 4   GLN E CA  1 
ATOM   5401 C  C   . GLN E 1 4   ? 14.697  -37.508 18.726  1.00 87.01  ? 4   GLN E C   1 
ATOM   5402 O  O   . GLN E 1 4   ? 13.954  -38.380 18.247  1.00 81.21  ? 4   GLN E O   1 
ATOM   5403 C  CB  . GLN E 1 4   ? 14.327  -35.406 17.387  1.00 87.50  ? 4   GLN E CB  1 
ATOM   5404 C  CG  . GLN E 1 4   ? 13.540  -36.128 16.281  1.00 88.14  ? 4   GLN E CG  1 
ATOM   5405 C  CD  . GLN E 1 4   ? 12.199  -35.474 15.974  1.00 87.11  ? 4   GLN E CD  1 
ATOM   5406 O  OE1 . GLN E 1 4   ? 12.079  -34.244 15.961  1.00 89.93  ? 4   GLN E OE1 1 
ATOM   5407 N  NE2 . GLN E 1 4   ? 11.181  -36.300 15.733  1.00 80.69  ? 4   GLN E NE2 1 
ATOM   5408 N  N   . VAL E 1 5   ? 15.912  -37.799 19.215  1.00 82.69  ? 5   VAL E N   1 
ATOM   5409 C  CA  . VAL E 1 5   ? 16.324  -39.197 19.373  1.00 77.08  ? 5   VAL E CA  1 
ATOM   5410 C  C   . VAL E 1 5   ? 15.815  -39.813 20.666  1.00 74.12  ? 5   VAL E C   1 
ATOM   5411 O  O   . VAL E 1 5   ? 15.960  -41.027 20.854  1.00 78.22  ? 5   VAL E O   1 
ATOM   5412 C  CB  . VAL E 1 5   ? 17.853  -39.417 19.339  1.00 74.37  ? 5   VAL E CB  1 
ATOM   5413 C  CG1 . VAL E 1 5   ? 18.465  -38.867 18.048  1.00 64.21  ? 5   VAL E CG1 1 
ATOM   5414 C  CG2 . VAL E 1 5   ? 18.545  -38.847 20.601  1.00 69.76  ? 5   VAL E CG2 1 
ATOM   5415 N  N   . ARG E 1 6   ? 15.230  -39.021 21.564  1.00 75.71  ? 6   ARG E N   1 
ATOM   5416 C  CA  . ARG E 1 6   ? 14.761  -39.561 22.833  1.00 78.84  ? 6   ARG E CA  1 
ATOM   5417 C  C   . ARG E 1 6   ? 13.588  -40.517 22.600  1.00 75.18  ? 6   ARG E C   1 
ATOM   5418 O  O   . ARG E 1 6   ? 12.680  -40.232 21.814  1.00 78.99  ? 6   ARG E O   1 
ATOM   5419 C  CB  . ARG E 1 6   ? 14.374  -38.426 23.789  1.00 78.44  ? 6   ARG E CB  1 
ATOM   5420 C  CG  . ARG E 1 6   ? 14.501  -38.807 25.268  1.00 76.80  ? 6   ARG E CG  1 
ATOM   5421 C  CD  . ARG E 1 6   ? 14.017  -37.711 26.227  1.00 80.71  ? 6   ARG E CD  1 
ATOM   5422 N  NE  . ARG E 1 6   ? 14.211  -38.108 27.627  1.00 79.32  ? 6   ARG E NE  1 
ATOM   5423 C  CZ  . ARG E 1 6   ? 15.029  -37.502 28.489  1.00 74.41  ? 6   ARG E CZ  1 
ATOM   5424 N  NH1 . ARG E 1 6   ? 15.124  -37.950 29.738  1.00 70.05  ? 6   ARG E NH1 1 
ATOM   5425 N  NH2 . ARG E 1 6   ? 15.738  -36.440 28.114  1.00 60.17  ? 6   ARG E NH2 1 
ATOM   5426 N  N   . GLN E 1 7   ? 13.638  -41.672 23.260  1.00 78.48  ? 7   GLN E N   1 
ATOM   5427 C  CA  . GLN E 1 7   ? 12.586  -42.684 23.156  1.00 84.62  ? 7   GLN E CA  1 
ATOM   5428 C  C   . GLN E 1 7   ? 12.701  -43.573 24.392  1.00 82.75  ? 7   GLN E C   1 
ATOM   5429 O  O   . GLN E 1 7   ? 13.671  -44.331 24.510  1.00 81.11  ? 7   GLN E O   1 
ATOM   5430 C  CB  . GLN E 1 7   ? 12.730  -43.493 21.862  1.00 79.62  ? 7   GLN E CB  1 
ATOM   5431 C  CG  . GLN E 1 7   ? 11.760  -44.674 21.724  1.00 84.99  ? 7   GLN E CG  1 
ATOM   5432 C  CD  . GLN E 1 7   ? 12.359  -45.888 20.983  1.00 98.52  ? 7   GLN E CD  1 
ATOM   5433 O  OE1 . GLN E 1 7   ? 13.456  -46.368 21.312  1.00 92.80  ? 7   GLN E OE1 1 
ATOM   5434 N  NE2 . GLN E 1 7   ? 11.625  -46.391 19.981  1.00 86.00  ? 7   GLN E NE2 1 
ATOM   5435 N  N   . ASN E 1 8   ? 11.740  -43.452 25.321  1.00 79.69  ? 8   ASN E N   1 
ATOM   5436 C  CA  . ASN E 1 8   ? 11.673  -44.305 26.510  1.00 85.88  ? 8   ASN E CA  1 
ATOM   5437 C  C   . ASN E 1 8   ? 12.850  -44.022 27.454  1.00 77.49  ? 8   ASN E C   1 
ATOM   5438 O  O   . ASN E 1 8   ? 13.641  -44.924 27.765  1.00 78.37  ? 8   ASN E O   1 
ATOM   5439 C  CB  . ASN E 1 8   ? 11.613  -45.788 26.073  1.00 87.23  ? 8   ASN E CB  1 
ATOM   5440 C  CG  . ASN E 1 8   ? 11.389  -46.764 27.234  1.00 89.58  ? 8   ASN E CG  1 
ATOM   5441 O  OD1 . ASN E 1 8   ? 10.406  -46.664 27.975  1.00 84.12  ? 8   ASN E OD1 1 
ATOM   5442 N  ND2 . ASN E 1 8   ? 12.300  -47.733 27.374  1.00 84.25  ? 8   ASN E ND2 1 
ATOM   5443 N  N   . TYR E 1 9   ? 12.974  -42.771 27.921  1.00 80.66  ? 9   TYR E N   1 
ATOM   5444 C  CA  . TYR E 1 9   ? 14.096  -42.346 28.774  1.00 79.76  ? 9   TYR E CA  1 
ATOM   5445 C  C   . TYR E 1 9   ? 13.574  -41.476 29.915  1.00 74.57  ? 9   TYR E C   1 
ATOM   5446 O  O   . TYR E 1 9   ? 13.284  -40.290 29.711  1.00 71.04  ? 9   TYR E O   1 
ATOM   5447 C  CB  . TYR E 1 9   ? 15.151  -41.593 27.971  1.00 74.55  ? 9   TYR E CB  1 
ATOM   5448 C  CG  . TYR E 1 9   ? 16.508  -41.518 28.651  1.00 73.87  ? 9   TYR E CG  1 
ATOM   5449 C  CD1 . TYR E 1 9   ? 17.117  -42.667 29.157  1.00 70.18  ? 9   TYR E CD1 1 
ATOM   5450 C  CD2 . TYR E 1 9   ? 17.181  -40.303 28.782  1.00 66.85  ? 9   TYR E CD2 1 
ATOM   5451 C  CE1 . TYR E 1 9   ? 18.350  -42.610 29.766  1.00 62.60  ? 9   TYR E CE1 1 
ATOM   5452 C  CE2 . TYR E 1 9   ? 18.417  -40.237 29.392  1.00 60.48  ? 9   TYR E CE2 1 
ATOM   5453 C  CZ  . TYR E 1 9   ? 18.999  -41.398 29.876  1.00 60.46  ? 9   TYR E CZ  1 
ATOM   5454 O  OH  . TYR E 1 9   ? 20.235  -41.350 30.479  1.00 60.58  ? 9   TYR E OH  1 
ATOM   5455 N  N   . HIS E 1 10  ? 13.498  -42.053 31.117  1.00 70.36  ? 10  HIS E N   1 
ATOM   5456 C  CA  . HIS E 1 10  ? 12.914  -41.347 32.247  1.00 68.21  ? 10  HIS E CA  1 
ATOM   5457 C  C   . HIS E 1 10  ? 13.831  -40.234 32.749  1.00 70.24  ? 10  HIS E C   1 
ATOM   5458 O  O   . HIS E 1 10  ? 15.061  -40.305 32.664  1.00 63.60  ? 10  HIS E O   1 
ATOM   5459 C  CB  . HIS E 1 10  ? 12.594  -42.306 33.398  1.00 72.39  ? 10  HIS E CB  1 
ATOM   5460 C  CG  . HIS E 1 10  ? 11.530  -41.796 34.328  1.00 77.67  ? 10  HIS E CG  1 
ATOM   5461 N  ND1 . HIS E 1 10  ? 11.819  -41.122 35.496  1.00 75.56  ? 10  HIS E ND1 1 
ATOM   5462 C  CD2 . HIS E 1 10  ? 10.177  -41.851 34.253  1.00 75.63  ? 10  HIS E CD2 1 
ATOM   5463 C  CE1 . HIS E 1 10  ? 10.692  -40.790 36.102  1.00 77.40  ? 10  HIS E CE1 1 
ATOM   5464 N  NE2 . HIS E 1 10  ? 9.681   -41.217 35.368  1.00 76.31  ? 10  HIS E NE2 1 
ATOM   5465 N  N   . GLU E 1 11  ? 13.195  -39.199 33.289  1.00 74.92  ? 11  GLU E N   1 
ATOM   5466 C  CA  . GLU E 1 11  ? 13.901  -38.033 33.790  1.00 65.03  ? 11  GLU E CA  1 
ATOM   5467 C  C   . GLU E 1 11  ? 14.799  -38.385 34.969  1.00 67.67  ? 11  GLU E C   1 
ATOM   5468 O  O   . GLU E 1 11  ? 15.873  -37.789 35.124  1.00 66.82  ? 11  GLU E O   1 
ATOM   5469 C  CB  . GLU E 1 11  ? 12.877  -36.965 34.183  1.00 71.55  ? 11  GLU E CB  1 
ATOM   5470 C  CG  . GLU E 1 11  ? 11.639  -36.878 33.240  1.00 83.89  ? 11  GLU E CG  1 
ATOM   5471 C  CD  . GLU E 1 11  ? 10.499  -37.875 33.587  1.00 91.34  ? 11  GLU E CD  1 
ATOM   5472 O  OE1 . GLU E 1 11  ? 10.273  -38.831 32.793  1.00 87.96  ? 11  GLU E OE1 1 
ATOM   5473 O  OE2 . GLU E 1 11  ? 9.832   -37.699 34.646  1.00 92.17  ? 11  GLU E OE2 1 
ATOM   5474 N  N   . ASP E 1 12  ? 14.381  -39.337 35.813  1.00 70.08  ? 12  ASP E N   1 
ATOM   5475 C  CA  . ASP E 1 12  ? 15.177  -39.723 36.977  1.00 68.69  ? 12  ASP E CA  1 
ATOM   5476 C  C   . ASP E 1 12  ? 16.338  -40.628 36.603  1.00 62.28  ? 12  ASP E C   1 
ATOM   5477 O  O   . ASP E 1 12  ? 17.317  -40.710 37.360  1.00 55.80  ? 12  ASP E O   1 
ATOM   5478 C  CB  . ASP E 1 12  ? 14.311  -40.429 38.027  1.00 67.69  ? 12  ASP E CB  1 
ATOM   5479 C  CG  . ASP E 1 12  ? 13.124  -39.591 38.469  1.00 75.98  ? 12  ASP E CG  1 
ATOM   5480 O  OD1 . ASP E 1 12  ? 13.253  -38.346 38.573  1.00 67.76  ? 12  ASP E OD1 1 
ATOM   5481 O  OD2 . ASP E 1 12  ? 12.053  -40.188 38.709  1.00 78.11  ? 12  ASP E OD2 1 
ATOM   5482 N  N   . CYS E 1 13  ? 16.229  -41.325 35.472  1.00 52.77  ? 13  CYS E N   1 
ATOM   5483 C  CA  . CYS E 1 13  ? 17.382  -42.013 34.910  1.00 61.13  ? 13  CYS E CA  1 
ATOM   5484 C  C   . CYS E 1 13  ? 18.447  -41.012 34.474  1.00 56.92  ? 13  CYS E C   1 
ATOM   5485 O  O   . CYS E 1 13  ? 19.630  -41.166 34.804  1.00 56.15  ? 13  CYS E O   1 
ATOM   5486 C  CB  . CYS E 1 13  ? 16.942  -42.880 33.731  1.00 58.53  ? 13  CYS E CB  1 
ATOM   5487 S  SG  . CYS E 1 13  ? 15.988  -44.338 34.207  1.00 66.82  ? 13  CYS E SG  1 
ATOM   5488 N  N   . GLU E 1 14  ? 18.034  -39.973 33.745  1.00 50.73  ? 14  GLU E N   1 
ATOM   5489 C  CA  . GLU E 1 14  ? 18.948  -38.913 33.332  1.00 54.91  ? 14  GLU E CA  1 
ATOM   5490 C  C   . GLU E 1 14  ? 19.745  -38.361 34.512  1.00 52.97  ? 14  GLU E C   1 
ATOM   5491 O  O   . GLU E 1 14  ? 20.980  -38.298 34.463  1.00 45.10  ? 14  GLU E O   1 
ATOM   5492 C  CB  . GLU E 1 14  ? 18.160  -37.801 32.646  1.00 58.73  ? 14  GLU E CB  1 
ATOM   5493 C  CG  . GLU E 1 14  ? 18.995  -36.654 32.104  1.00 53.62  ? 14  GLU E CG  1 
ATOM   5494 C  CD  . GLU E 1 14  ? 18.219  -35.820 31.089  1.00 60.48  ? 14  GLU E CD  1 
ATOM   5495 O  OE1 . GLU E 1 14  ? 17.007  -36.087 30.872  1.00 63.63  ? 14  GLU E OE1 1 
ATOM   5496 O  OE2 . GLU E 1 14  ? 18.825  -34.907 30.498  1.00 57.12  ? 14  GLU E OE2 1 
ATOM   5497 N  N   . ALA E 1 15  ? 19.052  -37.977 35.593  1.00 42.77  ? 15  ALA E N   1 
ATOM   5498 C  CA  . ALA E 1 15  ? 19.747  -37.434 36.756  1.00 42.88  ? 15  ALA E CA  1 
ATOM   5499 C  C   . ALA E 1 15  ? 20.670  -38.464 37.400  1.00 44.00  ? 15  ALA E C   1 
ATOM   5500 O  O   . ALA E 1 15  ? 21.736  -38.104 37.916  1.00 38.91  ? 15  ALA E O   1 
ATOM   5501 C  CB  . ALA E 1 15  ? 18.738  -36.906 37.781  1.00 35.10  ? 15  ALA E CB  1 
ATOM   5502 N  N   . SER E 1 16  ? 20.299  -39.746 37.372  1.00 45.09  ? 16  SER E N   1 
ATOM   5503 C  CA  . SER E 1 16  ? 21.147  -40.734 38.023  1.00 48.84  ? 16  SER E CA  1 
ATOM   5504 C  C   . SER E 1 16  ? 22.376  -41.048 37.185  1.00 46.59  ? 16  SER E C   1 
ATOM   5505 O  O   . SER E 1 16  ? 23.442  -41.311 37.749  1.00 40.24  ? 16  SER E O   1 
ATOM   5506 C  CB  . SER E 1 16  ? 20.359  -42.012 38.331  1.00 48.77  ? 16  SER E CB  1 
ATOM   5507 O  OG  . SER E 1 16  ? 19.636  -41.889 39.547  1.00 66.36  ? 16  SER E OG  1 
ATOM   5508 N  N   . ILE E 1 17  ? 22.254  -41.005 35.851  1.00 42.83  ? 17  ILE E N   1 
ATOM   5509 C  CA  . ILE E 1 17  ? 23.432  -41.149 35.000  1.00 44.04  ? 17  ILE E CA  1 
ATOM   5510 C  C   . ILE E 1 17  ? 24.423  -40.032 35.280  1.00 39.31  ? 17  ILE E C   1 
ATOM   5511 O  O   . ILE E 1 17  ? 25.634  -40.269 35.364  1.00 37.41  ? 17  ILE E O   1 
ATOM   5512 C  CB  . ILE E 1 17  ? 23.045  -41.176 33.511  1.00 46.85  ? 17  ILE E CB  1 
ATOM   5513 C  CG1 . ILE E 1 17  ? 22.408  -42.517 33.153  1.00 51.56  ? 17  ILE E CG1 1 
ATOM   5514 C  CG2 . ILE E 1 17  ? 24.293  -40.958 32.646  1.00 39.51  ? 17  ILE E CG2 1 
ATOM   5515 C  CD1 . ILE E 1 17  ? 23.321  -43.682 33.465  1.00 56.07  ? 17  ILE E CD1 1 
ATOM   5516 N  N   . ASN E 1 18  ? 23.927  -38.801 35.431  1.00 37.68  ? 18  ASN E N   1 
ATOM   5517 C  CA  . ASN E 1 18  ? 24.809  -37.681 35.737  1.00 37.70  ? 18  ASN E CA  1 
ATOM   5518 C  C   . ASN E 1 18  ? 25.493  -37.873 37.085  1.00 35.48  ? 18  ASN E C   1 
ATOM   5519 O  O   . ASN E 1 18  ? 26.680  -37.557 37.232  1.00 33.75  ? 18  ASN E O   1 
ATOM   5520 C  CB  . ASN E 1 18  ? 24.034  -36.363 35.712  1.00 35.22  ? 18  ASN E CB  1 
ATOM   5521 C  CG  . ASN E 1 18  ? 23.775  -35.854 34.293  1.00 41.53  ? 18  ASN E CG  1 
ATOM   5522 O  OD1 . ASN E 1 18  ? 24.588  -36.049 33.383  1.00 39.04  ? 18  ASN E OD1 1 
ATOM   5523 N  ND2 . ASN E 1 18  ? 22.627  -35.195 34.101  1.00 39.80  ? 18  ASN E ND2 1 
ATOM   5524 N  N   . LYS E 1 19  ? 24.769  -38.381 38.083  1.00 33.09  ? 19  LYS E N   1 
ATOM   5525 C  CA  . LYS E 1 19  ? 25.430  -38.675 39.352  1.00 40.80  ? 19  LYS E CA  1 
ATOM   5526 C  C   . LYS E 1 19  ? 26.564  -39.685 39.159  1.00 40.62  ? 19  LYS E C   1 
ATOM   5527 O  O   . LYS E 1 19  ? 27.643  -39.540 39.753  1.00 36.60  ? 19  LYS E O   1 
ATOM   5528 C  CB  . LYS E 1 19  ? 24.423  -39.191 40.382  1.00 39.00  ? 19  LYS E CB  1 
ATOM   5529 C  CG  . LYS E 1 19  ? 25.077  -39.522 41.719  1.00 47.19  ? 19  LYS E CG  1 
ATOM   5530 C  CD  . LYS E 1 19  ? 24.108  -40.075 42.747  1.00 44.30  ? 19  LYS E CD  1 
ATOM   5531 C  CE  . LYS E 1 19  ? 24.875  -40.467 44.006  1.00 54.99  ? 19  LYS E CE  1 
ATOM   5532 N  NZ  . LYS E 1 19  ? 24.141  -41.483 44.838  1.00 61.69  ? 19  LYS E NZ  1 
ATOM   5533 N  N   . GLN E 1 20  ? 26.345  -40.696 38.306  1.00 30.97  ? 20  GLN E N   1 
ATOM   5534 C  CA  . GLN E 1 20  ? 27.342  -41.739 38.095  1.00 36.21  ? 20  GLN E CA  1 
ATOM   5535 C  C   . GLN E 1 20  ? 28.554  -41.223 37.327  1.00 36.84  ? 20  GLN E C   1 
ATOM   5536 O  O   . GLN E 1 20  ? 29.677  -41.683 37.564  1.00 33.28  ? 20  GLN E O   1 
ATOM   5537 C  CB  . GLN E 1 20  ? 26.726  -42.916 37.343  1.00 35.19  ? 20  GLN E CB  1 
ATOM   5538 C  CG  . GLN E 1 20  ? 27.566  -44.170 37.391  1.00 38.53  ? 20  GLN E CG  1 
ATOM   5539 C  CD  . GLN E 1 20  ? 27.603  -44.818 38.784  1.00 47.49  ? 20  GLN E CD  1 
ATOM   5540 O  OE1 . GLN E 1 20  ? 26.734  -44.575 39.628  1.00 43.22  ? 20  GLN E OE1 1 
ATOM   5541 N  NE2 . GLN E 1 20  ? 28.617  -45.650 39.020  1.00 46.82  ? 20  GLN E NE2 1 
ATOM   5542 N  N   . ILE E 1 21  ? 28.352  -40.300 36.385  1.00 30.96  ? 21  ILE E N   1 
ATOM   5543 C  CA  . ILE E 1 21  ? 29.492  -39.684 35.725  1.00 33.54  ? 21  ILE E CA  1 
ATOM   5544 C  C   . ILE E 1 21  ? 30.400  -39.049 36.767  1.00 37.75  ? 21  ILE E C   1 
ATOM   5545 O  O   . ILE E 1 21  ? 31.629  -39.219 36.729  1.00 34.28  ? 21  ILE E O   1 
ATOM   5546 C  CB  . ILE E 1 21  ? 29.012  -38.666 34.675  1.00 33.68  ? 21  ILE E CB  1 
ATOM   5547 C  CG1 . ILE E 1 21  ? 28.283  -39.396 33.546  1.00 33.72  ? 21  ILE E CG1 1 
ATOM   5548 C  CG2 . ILE E 1 21  ? 30.196  -37.819 34.159  1.00 29.50  ? 21  ILE E CG2 1 
ATOM   5549 C  CD1 . ILE E 1 21  ? 27.152  -38.586 32.905  1.00 39.26  ? 21  ILE E CD1 1 
ATOM   5550 N  N   . ASN E 1 22  ? 29.792  -38.363 37.753  1.00 33.48  ? 22  ASN E N   1 
ATOM   5551 C  CA  . ASN E 1 22  ? 30.546  -37.673 38.792  1.00 32.78  ? 22  ASN E CA  1 
ATOM   5552 C  C   . ASN E 1 22  ? 31.288  -38.651 39.695  1.00 36.59  ? 22  ASN E C   1 
ATOM   5553 O  O   . ASN E 1 22  ? 32.427  -38.385 40.114  1.00 30.40  ? 22  ASN E O   1 
ATOM   5554 C  CB  . ASN E 1 22  ? 29.615  -36.810 39.627  1.00 29.18  ? 22  ASN E CB  1 
ATOM   5555 C  CG  . ASN E 1 22  ? 30.369  -35.904 40.528  1.00 35.71  ? 22  ASN E CG  1 
ATOM   5556 O  OD1 . ASN E 1 22  ? 30.746  -34.792 40.132  1.00 36.55  ? 22  ASN E OD1 1 
ATOM   5557 N  ND2 . ASN E 1 22  ? 30.672  -36.385 41.731  1.00 32.73  ? 22  ASN E ND2 1 
ATOM   5558 N  N   . MET E 1 23  ? 30.651  -39.780 40.019  1.00 32.91  ? 23  MET E N   1 
ATOM   5559 C  CA  . MET E 1 23  ? 31.311  -40.784 40.845  1.00 34.02  ? 23  MET E CA  1 
ATOM   5560 C  C   . MET E 1 23  ? 32.545  -41.347 40.150  1.00 34.05  ? 23  MET E C   1 
ATOM   5561 O  O   . MET E 1 23  ? 33.610  -41.476 40.770  1.00 36.43  ? 23  MET E O   1 
ATOM   5562 C  CB  . MET E 1 23  ? 30.333  -41.902 41.176  1.00 43.89  ? 23  MET E CB  1 
ATOM   5563 C  CG  . MET E 1 23  ? 29.111  -41.434 41.927  1.00 45.07  ? 23  MET E CG  1 
ATOM   5564 S  SD  . MET E 1 23  ? 29.534  -41.271 43.657  1.00 67.15  ? 23  MET E SD  1 
ATOM   5565 C  CE  . MET E 1 23  ? 29.583  -43.003 44.119  1.00 59.99  ? 23  MET E CE  1 
ATOM   5566 N  N   . GLU E 1 24  ? 32.428  -41.677 38.860  1.00 32.11  ? 24  GLU E N   1 
ATOM   5567 C  CA  . GLU E 1 24  ? 33.575  -42.220 38.133  1.00 37.81  ? 24  GLU E CA  1 
ATOM   5568 C  C   . GLU E 1 24  ? 34.707  -41.196 38.017  1.00 37.50  ? 24  GLU E C   1 
ATOM   5569 O  O   . GLU E 1 24  ? 35.887  -41.545 38.185  1.00 33.08  ? 24  GLU E O   1 
ATOM   5570 C  CB  . GLU E 1 24  ? 33.143  -42.721 36.753  1.00 41.12  ? 24  GLU E CB  1 
ATOM   5571 C  CG  . GLU E 1 24  ? 31.953  -43.718 36.750  1.00 41.57  ? 24  GLU E CG  1 
ATOM   5572 C  CD  . GLU E 1 24  ? 32.286  -45.077 37.355  1.00 53.98  ? 24  GLU E CD  1 
ATOM   5573 O  OE1 . GLU E 1 24  ? 33.464  -45.288 37.714  1.00 50.41  ? 24  GLU E OE1 1 
ATOM   5574 O  OE2 . GLU E 1 24  ? 31.371  -45.933 37.482  1.00 59.78  ? 24  GLU E OE2 1 
ATOM   5575 N  N   . LEU E 1 25  ? 34.378  -39.922 37.768  1.00 33.46  ? 25  LEU E N   1 
ATOM   5576 C  CA  . LEU E 1 25  ? 35.428  -38.903 37.738  1.00 31.67  ? 25  LEU E CA  1 
ATOM   5577 C  C   . LEU E 1 25  ? 36.081  -38.740 39.107  1.00 32.92  ? 25  LEU E C   1 
ATOM   5578 O  O   . LEU E 1 25  ? 37.294  -38.524 39.201  1.00 36.34  ? 25  LEU E O   1 
ATOM   5579 C  CB  . LEU E 1 25  ? 34.858  -37.576 37.261  1.00 33.96  ? 25  LEU E CB  1 
ATOM   5580 C  CG  . LEU E 1 25  ? 34.344  -37.595 35.833  1.00 30.52  ? 25  LEU E CG  1 
ATOM   5581 C  CD1 . LEU E 1 25  ? 33.502  -36.371 35.589  1.00 34.97  ? 25  LEU E CD1 1 
ATOM   5582 C  CD2 . LEU E 1 25  ? 35.518  -37.638 34.866  1.00 29.57  ? 25  LEU E CD2 1 
ATOM   5583 N  N   . TYR E 1 26  ? 35.296  -38.854 40.180  1.00 34.51  ? 26  TYR E N   1 
ATOM   5584 C  CA  . TYR E 1 26  ? 35.853  -38.729 41.523  1.00 33.87  ? 26  TYR E CA  1 
ATOM   5585 C  C   . TYR E 1 26  ? 36.761  -39.906 41.841  1.00 31.41  ? 26  TYR E C   1 
ATOM   5586 O  O   . TYR E 1 26  ? 37.908  -39.714 42.277  1.00 29.74  ? 26  TYR E O   1 
ATOM   5587 C  CB  . TYR E 1 26  ? 34.730  -38.618 42.561  1.00 30.50  ? 26  TYR E CB  1 
ATOM   5588 C  CG  . TYR E 1 26  ? 35.197  -38.816 43.987  1.00 27.90  ? 26  TYR E CG  1 
ATOM   5589 C  CD1 . TYR E 1 26  ? 35.890  -37.815 44.647  1.00 26.55  ? 26  TYR E CD1 1 
ATOM   5590 C  CD2 . TYR E 1 26  ? 34.945  -40.017 44.676  1.00 30.79  ? 26  TYR E CD2 1 
ATOM   5591 C  CE1 . TYR E 1 26  ? 36.322  -37.979 45.945  1.00 32.87  ? 26  TYR E CE1 1 
ATOM   5592 C  CE2 . TYR E 1 26  ? 35.379  -40.197 46.000  1.00 26.37  ? 26  TYR E CE2 1 
ATOM   5593 C  CZ  . TYR E 1 26  ? 36.063  -39.161 46.623  1.00 32.45  ? 26  TYR E CZ  1 
ATOM   5594 O  OH  . TYR E 1 26  ? 36.518  -39.280 47.924  1.00 44.28  ? 26  TYR E OH  1 
ATOM   5595 N  N   . ALA E 1 27  ? 36.251  -41.134 41.639  1.00 31.56  ? 27  ALA E N   1 
ATOM   5596 C  CA  . ALA E 1 27  ? 37.058  -42.355 41.599  1.00 36.26  ? 27  ALA E CA  1 
ATOM   5597 C  C   . ALA E 1 27  ? 38.387  -42.141 40.869  1.00 40.13  ? 27  ALA E C   1 
ATOM   5598 O  O   . ALA E 1 27  ? 39.455  -42.524 41.374  1.00 34.12  ? 27  ALA E O   1 
ATOM   5599 C  CB  . ALA E 1 27  ? 36.295  -43.484 40.907  1.00 31.52  ? 27  ALA E CB  1 
ATOM   5600 N  N   . SER E 1 28  ? 38.326  -41.521 39.685  1.00 28.40  ? 28  SER E N   1 
ATOM   5601 C  CA  . SER E 1 28  ? 39.531  -41.350 38.885  1.00 38.90  ? 28  SER E CA  1 
ATOM   5602 C  C   . SER E 1 28  ? 40.487  -40.373 39.564  1.00 37.82  ? 28  SER E C   1 
ATOM   5603 O  O   . SER E 1 28  ? 41.696  -40.634 39.659  1.00 36.15  ? 28  SER E O   1 
ATOM   5604 C  CB  . SER E 1 28  ? 39.134  -40.896 37.475  1.00 39.19  ? 28  SER E CB  1 
ATOM   5605 O  OG  . SER E 1 28  ? 40.213  -40.369 36.735  1.00 32.12  ? 28  SER E OG  1 
ATOM   5606 N  N   . TYR E 1 29  ? 39.942  -39.287 40.110  1.00 35.84  ? 29  TYR E N   1 
ATOM   5607 C  CA  . TYR E 1 29  ? 40.734  -38.323 40.877  1.00 33.57  ? 29  TYR E CA  1 
ATOM   5608 C  C   . TYR E 1 29  ? 41.420  -38.979 42.081  1.00 34.66  ? 29  TYR E C   1 
ATOM   5609 O  O   . TYR E 1 29  ? 42.624  -38.793 42.293  1.00 33.42  ? 29  TYR E O   1 
ATOM   5610 C  CB  . TYR E 1 29  ? 39.821  -37.179 41.319  1.00 33.78  ? 29  TYR E CB  1 
ATOM   5611 C  CG  . TYR E 1 29  ? 40.513  -35.883 41.640  1.00 32.84  ? 29  TYR E CG  1 
ATOM   5612 C  CD1 . TYR E 1 29  ? 41.810  -35.622 41.210  1.00 36.15  ? 29  TYR E CD1 1 
ATOM   5613 C  CD2 . TYR E 1 29  ? 39.853  -34.908 42.344  1.00 31.49  ? 29  TYR E CD2 1 
ATOM   5614 C  CE1 . TYR E 1 29  ? 42.433  -34.400 41.496  1.00 29.69  ? 29  TYR E CE1 1 
ATOM   5615 C  CE2 . TYR E 1 29  ? 40.456  -33.708 42.642  1.00 36.16  ? 29  TYR E CE2 1 
ATOM   5616 C  CZ  . TYR E 1 29  ? 41.738  -33.455 42.217  1.00 35.97  ? 29  TYR E CZ  1 
ATOM   5617 O  OH  . TYR E 1 29  ? 42.295  -32.241 42.525  1.00 36.57  ? 29  TYR E OH  1 
ATOM   5618 N  N   . VAL E 1 30  ? 40.664  -39.740 42.890  1.00 36.45  ? 30  VAL E N   1 
ATOM   5619 C  CA  . VAL E 1 30  ? 41.260  -40.457 44.025  1.00 34.16  ? 30  VAL E CA  1 
ATOM   5620 C  C   . VAL E 1 30  ? 42.446  -41.301 43.566  1.00 35.38  ? 30  VAL E C   1 
ATOM   5621 O  O   . VAL E 1 30  ? 43.521  -41.262 44.171  1.00 34.15  ? 30  VAL E O   1 
ATOM   5622 C  CB  . VAL E 1 30  ? 40.215  -41.338 44.731  1.00 34.00  ? 30  VAL E CB  1 
ATOM   5623 C  CG1 . VAL E 1 30  ? 40.894  -42.173 45.838  1.00 31.02  ? 30  VAL E CG1 1 
ATOM   5624 C  CG2 . VAL E 1 30  ? 39.079  -40.497 45.293  1.00 32.66  ? 30  VAL E CG2 1 
ATOM   5625 N  N   . TYR E 1 31  ? 42.269  -42.083 42.488  1.00 32.49  ? 31  TYR E N   1 
ATOM   5626 C  CA  . TYR E 1 31  ? 43.355  -42.958 42.047  1.00 37.82  ? 31  TYR E CA  1 
ATOM   5627 C  C   . TYR E 1 31  ? 44.531  -42.147 41.543  1.00 36.38  ? 31  TYR E C   1 
ATOM   5628 O  O   . TYR E 1 31  ? 45.681  -42.571 41.681  1.00 35.60  ? 31  TYR E O   1 
ATOM   5629 C  CB  . TYR E 1 31  ? 42.902  -43.919 40.952  1.00 33.60  ? 31  TYR E CB  1 
ATOM   5630 C  CG  . TYR E 1 31  ? 42.138  -45.127 41.418  1.00 36.14  ? 31  TYR E CG  1 
ATOM   5631 C  CD1 . TYR E 1 31  ? 42.629  -45.945 42.437  1.00 36.27  ? 31  TYR E CD1 1 
ATOM   5632 C  CD2 . TYR E 1 31  ? 40.920  -45.464 40.825  1.00 39.84  ? 31  TYR E CD2 1 
ATOM   5633 C  CE1 . TYR E 1 31  ? 41.923  -47.070 42.855  1.00 39.10  ? 31  TYR E CE1 1 
ATOM   5634 C  CE2 . TYR E 1 31  ? 40.205  -46.568 41.239  1.00 40.05  ? 31  TYR E CE2 1 
ATOM   5635 C  CZ  . TYR E 1 31  ? 40.705  -47.366 42.250  1.00 45.49  ? 31  TYR E CZ  1 
ATOM   5636 O  OH  . TYR E 1 31  ? 39.990  -48.470 42.642  1.00 45.21  ? 31  TYR E OH  1 
ATOM   5637 N  N   . LEU E 1 32  ? 44.256  -40.977 40.968  1.00 33.99  ? 32  LEU E N   1 
ATOM   5638 C  CA  . LEU E 1 32  ? 45.321  -40.035 40.647  1.00 34.71  ? 32  LEU E CA  1 
ATOM   5639 C  C   . LEU E 1 32  ? 46.107  -39.629 41.898  1.00 37.93  ? 32  LEU E C   1 
ATOM   5640 O  O   . LEU E 1 32  ? 47.343  -39.591 41.876  1.00 35.83  ? 32  LEU E O   1 
ATOM   5641 C  CB  . LEU E 1 32  ? 44.727  -38.811 39.951  1.00 33.21  ? 32  LEU E CB  1 
ATOM   5642 C  CG  . LEU E 1 32  ? 45.729  -37.948 39.189  1.00 38.36  ? 32  LEU E CG  1 
ATOM   5643 C  CD1 . LEU E 1 32  ? 46.218  -38.711 37.985  1.00 32.74  ? 32  LEU E CD1 1 
ATOM   5644 C  CD2 . LEU E 1 32  ? 45.106  -36.617 38.781  1.00 37.81  ? 32  LEU E CD2 1 
ATOM   5645 N  N   . SER E 1 33  ? 45.411  -39.291 42.995  1.00 34.38  ? 33  SER E N   1 
ATOM   5646 C  CA  . SER E 1 33  ? 46.112  -39.009 44.244  1.00 34.63  ? 33  SER E CA  1 
ATOM   5647 C  C   . SER E 1 33  ? 47.007  -40.172 44.636  1.00 37.17  ? 33  SER E C   1 
ATOM   5648 O  O   . SER E 1 33  ? 48.194  -39.983 44.912  1.00 37.55  ? 33  SER E O   1 
ATOM   5649 C  CB  . SER E 1 33  ? 45.132  -38.719 45.379  1.00 34.67  ? 33  SER E CB  1 
ATOM   5650 O  OG  . SER E 1 33  ? 45.736  -37.894 46.370  1.00 41.80  ? 33  SER E OG  1 
ATOM   5651 N  N   . MET E 1 34  ? 46.452  -41.390 44.653  1.00 34.33  ? 34  MET E N   1 
ATOM   5652 C  CA  . MET E 1 34  ? 47.218  -42.540 45.123  1.00 39.19  ? 34  MET E CA  1 
ATOM   5653 C  C   . MET E 1 34  ? 48.460  -42.742 44.274  1.00 39.98  ? 34  MET E C   1 
ATOM   5654 O  O   . MET E 1 34  ? 49.539  -43.038 44.798  1.00 39.35  ? 34  MET E O   1 
ATOM   5655 C  CB  . MET E 1 34  ? 46.359  -43.809 45.113  1.00 35.74  ? 34  MET E CB  1 
ATOM   5656 C  CG  . MET E 1 34  ? 45.295  -43.861 46.189  1.00 40.79  ? 34  MET E CG  1 
ATOM   5657 S  SD  . MET E 1 34  ? 44.220  -45.309 46.070  1.00 40.34  ? 34  MET E SD  1 
ATOM   5658 C  CE  . MET E 1 34  ? 43.020  -44.916 47.351  1.00 37.48  ? 34  MET E CE  1 
ATOM   5659 N  N   . ALA E 1 35  ? 48.322  -42.566 42.958  1.00 38.54  ? 35  ALA E N   1 
ATOM   5660 C  CA  . ALA E 1 35  ? 49.418  -42.830 42.042  1.00 37.02  ? 35  ALA E CA  1 
ATOM   5661 C  C   . ALA E 1 35  ? 50.624  -41.958 42.362  1.00 41.31  ? 35  ALA E C   1 
ATOM   5662 O  O   . ALA E 1 35  ? 51.740  -42.463 42.535  1.00 40.27  ? 35  ALA E O   1 
ATOM   5663 C  CB  . ALA E 1 35  ? 48.946  -42.607 40.612  1.00 39.01  ? 35  ALA E CB  1 
ATOM   5664 N  N   . TYR E 1 36  ? 50.412  -40.644 42.485  1.00 41.16  ? 36  TYR E N   1 
ATOM   5665 C  CA  . TYR E 1 36  ? 51.533  -39.745 42.701  1.00 36.89  ? 36  TYR E CA  1 
ATOM   5666 C  C   . TYR E 1 36  ? 51.968  -39.712 44.148  1.00 38.46  ? 36  TYR E C   1 
ATOM   5667 O  O   . TYR E 1 36  ? 53.082  -39.259 44.434  1.00 44.09  ? 36  TYR E O   1 
ATOM   5668 C  CB  . TYR E 1 36  ? 51.197  -38.335 42.199  1.00 36.89  ? 36  TYR E CB  1 
ATOM   5669 C  CG  . TYR E 1 36  ? 51.263  -38.295 40.702  1.00 41.13  ? 36  TYR E CG  1 
ATOM   5670 C  CD1 . TYR E 1 36  ? 50.172  -38.702 39.933  1.00 37.93  ? 36  TYR E CD1 1 
ATOM   5671 C  CD2 . TYR E 1 36  ? 52.430  -37.935 40.049  1.00 36.62  ? 36  TYR E CD2 1 
ATOM   5672 C  CE1 . TYR E 1 36  ? 50.228  -38.700 38.556  1.00 42.15  ? 36  TYR E CE1 1 
ATOM   5673 C  CE2 . TYR E 1 36  ? 52.499  -37.938 38.664  1.00 41.40  ? 36  TYR E CE2 1 
ATOM   5674 C  CZ  . TYR E 1 36  ? 51.391  -38.325 37.923  1.00 44.03  ? 36  TYR E CZ  1 
ATOM   5675 O  OH  . TYR E 1 36  ? 51.437  -38.345 36.544  1.00 49.86  ? 36  TYR E OH  1 
ATOM   5676 N  N   . TYR E 1 37  ? 51.140  -40.191 45.070  1.00 35.06  ? 37  TYR E N   1 
ATOM   5677 C  CA  . TYR E 1 37  ? 51.639  -40.346 46.427  1.00 36.80  ? 37  TYR E CA  1 
ATOM   5678 C  C   . TYR E 1 37  ? 52.676  -41.458 46.477  1.00 43.94  ? 37  TYR E C   1 
ATOM   5679 O  O   . TYR E 1 37  ? 53.702  -41.326 47.152  1.00 41.76  ? 37  TYR E O   1 
ATOM   5680 C  CB  . TYR E 1 37  ? 50.488  -40.616 47.392  1.00 37.91  ? 37  TYR E CB  1 
ATOM   5681 C  CG  . TYR E 1 37  ? 50.911  -41.203 48.723  1.00 42.67  ? 37  TYR E CG  1 
ATOM   5682 C  CD1 . TYR E 1 37  ? 51.392  -40.395 49.753  1.00 42.55  ? 37  TYR E CD1 1 
ATOM   5683 C  CD2 . TYR E 1 37  ? 50.821  -42.573 48.957  1.00 44.03  ? 37  TYR E CD2 1 
ATOM   5684 C  CE1 . TYR E 1 37  ? 51.775  -40.944 50.973  1.00 41.78  ? 37  TYR E CE1 1 
ATOM   5685 C  CE2 . TYR E 1 37  ? 51.209  -43.123 50.177  1.00 39.88  ? 37  TYR E CE2 1 
ATOM   5686 C  CZ  . TYR E 1 37  ? 51.674  -42.310 51.170  1.00 39.21  ? 37  TYR E CZ  1 
ATOM   5687 O  OH  . TYR E 1 37  ? 52.041  -42.880 52.361  1.00 46.97  ? 37  TYR E OH  1 
ATOM   5688 N  N   . PHE E 1 38  ? 52.452  -42.543 45.732  1.00 43.33  ? 38  PHE E N   1 
ATOM   5689 C  CA  . PHE E 1 38  ? 53.416  -43.635 45.716  1.00 44.03  ? 38  PHE E CA  1 
ATOM   5690 C  C   . PHE E 1 38  ? 54.632  -43.322 44.862  1.00 41.67  ? 38  PHE E C   1 
ATOM   5691 O  O   . PHE E 1 38  ? 55.570  -44.127 44.828  1.00 39.28  ? 38  PHE E O   1 
ATOM   5692 C  CB  . PHE E 1 38  ? 52.737  -44.930 45.259  1.00 41.12  ? 38  PHE E CB  1 
ATOM   5693 C  CG  . PHE E 1 38  ? 51.878  -45.525 46.317  1.00 40.98  ? 38  PHE E CG  1 
ATOM   5694 C  CD1 . PHE E 1 38  ? 52.450  -46.221 47.373  1.00 41.57  ? 38  PHE E CD1 1 
ATOM   5695 C  CD2 . PHE E 1 38  ? 50.511  -45.332 46.307  1.00 40.71  ? 38  PHE E CD2 1 
ATOM   5696 C  CE1 . PHE E 1 38  ? 51.654  -46.745 48.395  1.00 42.24  ? 38  PHE E CE1 1 
ATOM   5697 C  CE2 . PHE E 1 38  ? 49.703  -45.849 47.332  1.00 42.39  ? 38  PHE E CE2 1 
ATOM   5698 C  CZ  . PHE E 1 38  ? 50.278  -46.559 48.375  1.00 38.67  ? 38  PHE E CZ  1 
ATOM   5699 N  N   . GLU E 1 39  ? 54.635  -42.171 44.192  1.00 44.16  ? 39  GLU E N   1 
ATOM   5700 C  CA  . GLU E 1 39  ? 55.807  -41.666 43.493  1.00 44.64  ? 39  GLU E CA  1 
ATOM   5701 C  C   . GLU E 1 39  ? 56.585  -40.658 44.322  1.00 38.89  ? 39  GLU E C   1 
ATOM   5702 O  O   . GLU E 1 39  ? 57.606  -40.152 43.856  1.00 45.03  ? 39  GLU E O   1 
ATOM   5703 C  CB  . GLU E 1 39  ? 55.401  -41.052 42.149  1.00 41.97  ? 39  GLU E CB  1 
ATOM   5704 C  CG  . GLU E 1 39  ? 55.098  -42.116 41.090  1.00 41.68  ? 39  GLU E CG  1 
ATOM   5705 C  CD  . GLU E 1 39  ? 54.943  -41.557 39.682  1.00 51.37  ? 39  GLU E CD  1 
ATOM   5706 O  OE1 . GLU E 1 39  ? 55.272  -40.364 39.461  1.00 50.61  ? 39  GLU E OE1 1 
ATOM   5707 O  OE2 . GLU E 1 39  ? 54.502  -42.326 38.792  1.00 54.63  ? 39  GLU E OE2 1 
ATOM   5708 N  N   . ARG E 1 40  ? 56.143  -40.381 45.548  1.00 39.76  ? 40  ARG E N   1 
ATOM   5709 C  CA  . ARG E 1 40  ? 56.889  -39.494 46.426  1.00 43.61  ? 40  ARG E CA  1 
ATOM   5710 C  C   . ARG E 1 40  ? 58.265  -40.083 46.713  1.00 46.75  ? 40  ARG E C   1 
ATOM   5711 O  O   . ARG E 1 40  ? 58.447  -41.301 46.764  1.00 40.80  ? 40  ARG E O   1 
ATOM   5712 C  CB  . ARG E 1 40  ? 56.132  -39.270 47.734  1.00 42.98  ? 40  ARG E CB  1 
ATOM   5713 C  CG  . ARG E 1 40  ? 55.168  -38.115 47.698  1.00 43.95  ? 40  ARG E CG  1 
ATOM   5714 C  CD  . ARG E 1 40  ? 54.168  -38.140 48.876  1.00 46.17  ? 40  ARG E CD  1 
ATOM   5715 N  NE  . ARG E 1 40  ? 54.810  -38.421 50.163  1.00 61.20  ? 40  ARG E NE  1 
ATOM   5716 C  CZ  . ARG E 1 40  ? 54.240  -38.257 51.362  1.00 63.37  ? 40  ARG E CZ  1 
ATOM   5717 N  NH1 . ARG E 1 40  ? 52.995  -37.784 51.458  1.00 67.52  ? 40  ARG E NH1 1 
ATOM   5718 N  NH2 . ARG E 1 40  ? 54.917  -38.562 52.475  1.00 51.51  ? 40  ARG E NH2 1 
ATOM   5719 N  N   . ASP E 1 41  ? 59.242  -39.198 46.902  1.00 54.39  ? 41  ASP E N   1 
ATOM   5720 C  CA  . ASP E 1 41  ? 60.608  -39.627 47.157  1.00 53.60  ? 41  ASP E CA  1 
ATOM   5721 C  C   . ASP E 1 41  ? 60.771  -40.342 48.495  1.00 55.26  ? 41  ASP E C   1 
ATOM   5722 O  O   . ASP E 1 41  ? 61.812  -40.974 48.712  1.00 61.29  ? 41  ASP E O   1 
ATOM   5723 C  CB  . ASP E 1 41  ? 61.547  -38.426 47.091  1.00 63.61  ? 41  ASP E CB  1 
ATOM   5724 C  CG  . ASP E 1 41  ? 61.469  -37.558 48.332  1.00 70.16  ? 41  ASP E CG  1 
ATOM   5725 O  OD1 . ASP E 1 41  ? 60.549  -36.706 48.424  1.00 71.09  ? 41  ASP E OD1 1 
ATOM   5726 O  OD2 . ASP E 1 41  ? 62.333  -37.740 49.222  1.00 77.51  ? 41  ASP E OD2 1 
ATOM   5727 N  N   . ASP E 1 42  ? 59.790  -40.268 49.395  1.00 46.64  ? 42  ASP E N   1 
ATOM   5728 C  CA  . ASP E 1 42  ? 59.828  -41.040 50.630  1.00 45.84  ? 42  ASP E CA  1 
ATOM   5729 C  C   . ASP E 1 42  ? 58.898  -42.249 50.593  1.00 44.11  ? 42  ASP E C   1 
ATOM   5730 O  O   . ASP E 1 42  ? 58.662  -42.870 51.636  1.00 42.33  ? 42  ASP E O   1 
ATOM   5731 C  CB  . ASP E 1 42  ? 59.503  -40.157 51.850  1.00 49.35  ? 42  ASP E CB  1 
ATOM   5732 C  CG  . ASP E 1 42  ? 58.244  -39.298 51.675  1.00 50.24  ? 42  ASP E CG  1 
ATOM   5733 O  OD1 . ASP E 1 42  ? 57.399  -39.572 50.801  1.00 48.83  ? 42  ASP E OD1 1 
ATOM   5734 O  OD2 . ASP E 1 42  ? 58.103  -38.332 52.443  1.00 55.30  ? 42  ASP E OD2 1 
ATOM   5735 N  N   . VAL E 1 43  ? 58.368  -42.599 49.424  1.00 40.19  ? 43  VAL E N   1 
ATOM   5736 C  CA  . VAL E 1 43  ? 57.510  -43.771 49.312  1.00 43.76  ? 43  VAL E CA  1 
ATOM   5737 C  C   . VAL E 1 43  ? 58.091  -44.712 48.254  1.00 42.07  ? 43  VAL E C   1 
ATOM   5738 O  O   . VAL E 1 43  ? 58.405  -45.866 48.553  1.00 41.41  ? 43  VAL E O   1 
ATOM   5739 C  CB  . VAL E 1 43  ? 56.051  -43.362 49.009  1.00 41.45  ? 43  VAL E CB  1 
ATOM   5740 C  CG1 . VAL E 1 43  ? 55.154  -44.581 48.929  1.00 36.20  ? 43  VAL E CG1 1 
ATOM   5741 C  CG2 . VAL E 1 43  ? 55.527  -42.402 50.081  1.00 39.52  ? 43  VAL E CG2 1 
ATOM   5742 N  N   . CYS E 1 44  ? 58.242  -44.228 47.019  1.00 43.21  ? 44  CYS E N   1 
ATOM   5743 C  CA  . CYS E 1 44  ? 58.936  -44.933 45.932  1.00 43.59  ? 44  CYS E CA  1 
ATOM   5744 C  C   . CYS E 1 44  ? 58.451  -46.374 45.770  1.00 41.31  ? 44  CYS E C   1 
ATOM   5745 O  O   . CYS E 1 44  ? 59.219  -47.340 45.833  1.00 42.03  ? 44  CYS E O   1 
ATOM   5746 C  CB  . CYS E 1 44  ? 60.462  -44.897 46.112  1.00 45.96  ? 44  CYS E CB  1 
ATOM   5747 S  SG  . CYS E 1 44  ? 61.165  -43.269 46.630  1.00 67.02  ? 44  CYS E SG  1 
ATOM   5748 N  N   . LEU E 1 45  ? 57.154  -46.513 45.518  1.00 37.48  ? 45  LEU E N   1 
ATOM   5749 C  CA  . LEU E 1 45  ? 56.589  -47.812 45.153  1.00 42.45  ? 45  LEU E CA  1 
ATOM   5750 C  C   . LEU E 1 45  ? 56.054  -47.690 43.735  1.00 42.34  ? 45  LEU E C   1 
ATOM   5751 O  O   . LEU E 1 45  ? 54.879  -47.333 43.521  1.00 45.74  ? 45  LEU E O   1 
ATOM   5752 C  CB  . LEU E 1 45  ? 55.538  -48.250 46.167  1.00 36.22  ? 45  LEU E CB  1 
ATOM   5753 C  CG  . LEU E 1 45  ? 56.200  -48.676 47.477  1.00 38.31  ? 45  LEU E CG  1 
ATOM   5754 C  CD1 . LEU E 1 45  ? 55.161  -48.788 48.600  1.00 43.80  ? 45  LEU E CD1 1 
ATOM   5755 C  CD2 . LEU E 1 45  ? 56.942  -50.000 47.299  1.00 37.20  ? 45  LEU E CD2 1 
ATOM   5756 N  N   . PRO E 1 46  ? 56.896  -47.927 42.719  1.00 46.12  ? 46  PRO E N   1 
ATOM   5757 C  CA  . PRO E 1 46  ? 56.455  -47.716 41.331  1.00 39.54  ? 46  PRO E CA  1 
ATOM   5758 C  C   . PRO E 1 46  ? 55.397  -48.699 40.873  1.00 40.31  ? 46  PRO E C   1 
ATOM   5759 O  O   . PRO E 1 46  ? 54.590  -48.336 40.005  1.00 49.45  ? 46  PRO E O   1 
ATOM   5760 C  CB  . PRO E 1 46  ? 57.755  -47.862 40.516  1.00 43.10  ? 46  PRO E CB  1 
ATOM   5761 C  CG  . PRO E 1 46  ? 58.674  -48.648 41.394  1.00 41.06  ? 46  PRO E CG  1 
ATOM   5762 C  CD  . PRO E 1 46  ? 58.341  -48.222 42.797  1.00 45.04  ? 46  PRO E CD  1 
ATOM   5763 N  N   . GLY E 1 47  ? 55.384  -49.925 41.405  1.00 38.89  ? 47  GLY E N   1 
ATOM   5764 C  CA  . GLY E 1 47  ? 54.317  -50.879 41.152  1.00 37.89  ? 47  GLY E CA  1 
ATOM   5765 C  C   . GLY E 1 47  ? 52.942  -50.361 41.537  1.00 43.01  ? 47  GLY E C   1 
ATOM   5766 O  O   . GLY E 1 47  ? 52.055  -50.251 40.678  1.00 41.03  ? 47  GLY E O   1 
ATOM   5767 N  N   . PHE E 1 48  ? 52.745  -50.032 42.824  1.00 44.06  ? 48  PHE E N   1 
ATOM   5768 C  CA  . PHE E 1 48  ? 51.498  -49.388 43.243  1.00 40.03  ? 48  PHE E CA  1 
ATOM   5769 C  C   . PHE E 1 48  ? 51.214  -48.149 42.401  1.00 38.20  ? 48  PHE E C   1 
ATOM   5770 O  O   . PHE E 1 48  ? 50.074  -47.921 41.969  1.00 31.83  ? 48  PHE E O   1 
ATOM   5771 C  CB  . PHE E 1 48  ? 51.558  -48.986 44.717  1.00 36.29  ? 48  PHE E CB  1 
ATOM   5772 C  CG  . PHE E 1 48  ? 51.486  -50.131 45.676  1.00 39.32  ? 48  PHE E CG  1 
ATOM   5773 C  CD1 . PHE E 1 48  ? 52.634  -50.800 46.065  1.00 44.78  ? 48  PHE E CD1 1 
ATOM   5774 C  CD2 . PHE E 1 48  ? 50.287  -50.515 46.224  1.00 40.19  ? 48  PHE E CD2 1 
ATOM   5775 C  CE1 . PHE E 1 48  ? 52.581  -51.842 46.970  1.00 44.79  ? 48  PHE E CE1 1 
ATOM   5776 C  CE2 . PHE E 1 48  ? 50.229  -51.563 47.140  1.00 43.76  ? 48  PHE E CE2 1 
ATOM   5777 C  CZ  . PHE E 1 48  ? 51.375  -52.223 47.508  1.00 44.63  ? 48  PHE E CZ  1 
ATOM   5778 N  N   . ALA E 1 49  ? 52.250  -47.342 42.152  1.00 32.66  ? 49  ALA E N   1 
ATOM   5779 C  CA  . ALA E 1 49  ? 52.048  -46.099 41.421  1.00 40.05  ? 49  ALA E CA  1 
ATOM   5780 C  C   . ALA E 1 49  ? 51.457  -46.368 40.040  1.00 41.00  ? 49  ALA E C   1 
ATOM   5781 O  O   . ALA E 1 49  ? 50.495  -45.702 39.629  1.00 38.20  ? 49  ALA E O   1 
ATOM   5782 C  CB  . ALA E 1 49  ? 53.366  -45.325 41.318  1.00 32.38  ? 49  ALA E CB  1 
ATOM   5783 N  N   . LYS E 1 50  ? 52.005  -47.350 39.318  1.00 33.88  ? 50  LYS E N   1 
ATOM   5784 C  CA  . LYS E 1 50  ? 51.488  -47.662 37.989  1.00 37.19  ? 50  LYS E CA  1 
ATOM   5785 C  C   . LYS E 1 50  ? 50.070  -48.221 38.078  1.00 44.58  ? 50  LYS E C   1 
ATOM   5786 O  O   . LYS E 1 50  ? 49.193  -47.852 37.287  1.00 44.22  ? 50  LYS E O   1 
ATOM   5787 C  CB  . LYS E 1 50  ? 52.438  -48.642 37.293  1.00 41.15  ? 50  LYS E CB  1 
ATOM   5788 C  CG  . LYS E 1 50  ? 51.976  -49.173 35.939  1.00 45.22  ? 50  LYS E CG  1 
ATOM   5789 C  CD  . LYS E 1 50  ? 53.145  -49.781 35.159  1.00 51.59  ? 50  LYS E CD  1 
ATOM   5790 C  CE  . LYS E 1 50  ? 52.682  -50.657 34.000  1.00 61.73  ? 50  LYS E CE  1 
ATOM   5791 N  NZ  . LYS E 1 50  ? 52.581  -52.092 34.385  1.00 67.25  ? 50  LYS E NZ  1 
ATOM   5792 N  N   . PHE E 1 51  ? 49.819  -49.068 39.076  1.00 36.66  ? 51  PHE E N   1 
ATOM   5793 C  CA  . PHE E 1 51  ? 48.501  -49.663 39.249  1.00 36.72  ? 51  PHE E CA  1 
ATOM   5794 C  C   . PHE E 1 51  ? 47.414  -48.605 39.432  1.00 42.48  ? 51  PHE E C   1 
ATOM   5795 O  O   . PHE E 1 51  ? 46.346  -48.674 38.802  1.00 39.40  ? 51  PHE E O   1 
ATOM   5796 C  CB  . PHE E 1 51  ? 48.536  -50.597 40.447  1.00 36.20  ? 51  PHE E CB  1 
ATOM   5797 C  CG  . PHE E 1 51  ? 47.241  -51.252 40.723  1.00 36.19  ? 51  PHE E CG  1 
ATOM   5798 C  CD1 . PHE E 1 51  ? 46.875  -52.380 40.028  1.00 29.66  ? 51  PHE E CD1 1 
ATOM   5799 C  CD2 . PHE E 1 51  ? 46.382  -50.740 41.686  1.00 35.35  ? 51  PHE E CD2 1 
ATOM   5800 C  CE1 . PHE E 1 51  ? 45.653  -52.993 40.281  1.00 39.59  ? 51  PHE E CE1 1 
ATOM   5801 C  CE2 . PHE E 1 51  ? 45.181  -51.348 41.951  1.00 32.52  ? 51  PHE E CE2 1 
ATOM   5802 C  CZ  . PHE E 1 51  ? 44.810  -52.477 41.250  1.00 33.03  ? 51  PHE E CZ  1 
ATOM   5803 N  N   . PHE E 1 52  ? 47.664  -47.623 40.304  1.00 35.60  ? 52  PHE E N   1 
ATOM   5804 C  CA  . PHE E 1 52  ? 46.650  -46.620 40.582  1.00 35.79  ? 52  PHE E CA  1 
ATOM   5805 C  C   . PHE E 1 52  ? 46.515  -45.648 39.421  1.00 40.27  ? 52  PHE E C   1 
ATOM   5806 O  O   . PHE E 1 52  ? 45.414  -45.148 39.152  1.00 38.67  ? 52  PHE E O   1 
ATOM   5807 C  CB  . PHE E 1 52  ? 46.982  -45.903 41.895  1.00 33.30  ? 52  PHE E CB  1 
ATOM   5808 C  CG  . PHE E 1 52  ? 46.860  -46.792 43.104  1.00 36.88  ? 52  PHE E CG  1 
ATOM   5809 C  CD1 . PHE E 1 52  ? 45.746  -47.606 43.265  1.00 33.84  ? 52  PHE E CD1 1 
ATOM   5810 C  CD2 . PHE E 1 52  ? 47.881  -46.854 44.056  1.00 37.38  ? 52  PHE E CD2 1 
ATOM   5811 C  CE1 . PHE E 1 52  ? 45.643  -48.450 44.349  1.00 37.06  ? 52  PHE E CE1 1 
ATOM   5812 C  CE2 . PHE E 1 52  ? 47.779  -47.683 45.160  1.00 35.47  ? 52  PHE E CE2 1 
ATOM   5813 C  CZ  . PHE E 1 52  ? 46.654  -48.489 45.305  1.00 42.06  ? 52  PHE E CZ  1 
ATOM   5814 N  N   . LYS E 1 53  ? 47.608  -45.418 38.693  1.00 38.54  ? 53  LYS E N   1 
ATOM   5815 C  CA  . LYS E 1 53  ? 47.561  -44.523 37.546  1.00 41.78  ? 53  LYS E CA  1 
ATOM   5816 C  C   . LYS E 1 53  ? 46.796  -45.156 36.394  1.00 42.22  ? 53  LYS E C   1 
ATOM   5817 O  O   . LYS E 1 53  ? 46.179  -44.450 35.590  1.00 48.51  ? 53  LYS E O   1 
ATOM   5818 C  CB  . LYS E 1 53  ? 48.983  -44.140 37.120  1.00 39.48  ? 53  LYS E CB  1 
ATOM   5819 C  CG  . LYS E 1 53  ? 49.035  -43.138 35.998  1.00 45.67  ? 53  LYS E CG  1 
ATOM   5820 C  CD  . LYS E 1 53  ? 50.146  -42.087 36.207  1.00 56.88  ? 53  LYS E CD  1 
ATOM   5821 C  CE  . LYS E 1 53  ? 51.284  -42.557 37.145  1.00 60.89  ? 53  LYS E CE  1 
ATOM   5822 N  NZ  . LYS E 1 53  ? 52.508  -41.668 37.059  1.00 59.74  ? 53  LYS E NZ  1 
ATOM   5823 N  N   . GLU E 1 54  ? 46.803  -46.480 36.306  1.00 47.39  ? 54  GLU E N   1 
ATOM   5824 C  CA  . GLU E 1 54  ? 45.993  -47.123 35.285  1.00 46.06  ? 54  GLU E CA  1 
ATOM   5825 C  C   . GLU E 1 54  ? 44.541  -47.199 35.727  1.00 46.63  ? 54  GLU E C   1 
ATOM   5826 O  O   . GLU E 1 54  ? 43.624  -46.966 34.924  1.00 44.44  ? 54  GLU E O   1 
ATOM   5827 C  CB  . GLU E 1 54  ? 46.559  -48.503 34.964  1.00 40.22  ? 54  GLU E CB  1 
ATOM   5828 C  CG  . GLU E 1 54  ? 47.788  -48.441 34.087  1.00 44.80  ? 54  GLU E CG  1 
ATOM   5829 C  CD  . GLU E 1 54  ? 48.509  -49.785 33.948  1.00 60.57  ? 54  GLU E CD  1 
ATOM   5830 O  OE1 . GLU E 1 54  ? 48.100  -50.774 34.605  1.00 57.14  ? 54  GLU E OE1 1 
ATOM   5831 O  OE2 . GLU E 1 54  ? 49.488  -49.846 33.167  1.00 63.72  ? 54  GLU E OE2 1 
ATOM   5832 N  N   . SER E 1 55  ? 44.314  -47.484 37.009  1.00 39.77  ? 55  SER E N   1 
ATOM   5833 C  CA  . SER E 1 55  ? 42.955  -47.425 37.519  1.00 39.43  ? 55  SER E CA  1 
ATOM   5834 C  C   . SER E 1 55  ? 42.375  -46.025 37.349  1.00 43.33  ? 55  SER E C   1 
ATOM   5835 O  O   . SER E 1 55  ? 41.183  -45.870 37.048  1.00 43.77  ? 55  SER E O   1 
ATOM   5836 C  CB  . SER E 1 55  ? 42.918  -47.866 38.984  1.00 36.67  ? 55  SER E CB  1 
ATOM   5837 O  OG  . SER E 1 55  ? 43.514  -49.140 39.152  1.00 45.10  ? 55  SER E OG  1 
ATOM   5838 N  N   . SER E 1 56  ? 43.202  -44.986 37.510  1.00 36.23  ? 56  SER E N   1 
ATOM   5839 C  CA  . SER E 1 56  ? 42.652  -43.647 37.364  1.00 41.98  ? 56  SER E CA  1 
ATOM   5840 C  C   . SER E 1 56  ? 42.225  -43.388 35.919  1.00 40.56  ? 56  SER E C   1 
ATOM   5841 O  O   . SER E 1 56  ? 41.205  -42.729 35.677  1.00 36.76  ? 56  SER E O   1 
ATOM   5842 C  CB  . SER E 1 56  ? 43.648  -42.598 37.832  1.00 33.79  ? 56  SER E CB  1 
ATOM   5843 O  OG  . SER E 1 56  ? 43.351  -41.353 37.221  1.00 37.04  ? 56  SER E OG  1 
ATOM   5844 N  N   . ASP E 1 57  ? 42.983  -43.916 34.950  1.00 40.82  ? 57  ASP E N   1 
ATOM   5845 C  CA  . ASP E 1 57  ? 42.604  -43.801 33.537  1.00 43.65  ? 57  ASP E CA  1 
ATOM   5846 C  C   . ASP E 1 57  ? 41.326  -44.579 33.235  1.00 45.09  ? 57  ASP E C   1 
ATOM   5847 O  O   . ASP E 1 57  ? 40.410  -44.064 32.574  1.00 38.08  ? 57  ASP E O   1 
ATOM   5848 C  CB  . ASP E 1 57  ? 43.726  -44.317 32.639  1.00 40.63  ? 57  ASP E CB  1 
ATOM   5849 C  CG  . ASP E 1 57  ? 44.926  -43.409 32.605  1.00 41.83  ? 57  ASP E CG  1 
ATOM   5850 O  OD1 . ASP E 1 57  ? 44.784  -42.194 32.867  1.00 45.57  ? 57  ASP E OD1 1 
ATOM   5851 O  OD2 . ASP E 1 57  ? 46.020  -43.921 32.283  1.00 40.32  ? 57  ASP E OD2 1 
ATOM   5852 N  N   . GLU E 1 58  ? 41.273  -45.843 33.677  1.00 40.74  ? 58  GLU E N   1 
ATOM   5853 C  CA  . GLU E 1 58  ? 40.077  -46.661 33.499  1.00 38.43  ? 58  GLU E CA  1 
ATOM   5854 C  C   . GLU E 1 58  ? 38.840  -45.955 34.032  1.00 44.20  ? 58  GLU E C   1 
ATOM   5855 O  O   . GLU E 1 58  ? 37.799  -45.938 33.372  1.00 44.20  ? 58  GLU E O   1 
ATOM   5856 C  CB  . GLU E 1 58  ? 40.239  -48.009 34.206  1.00 42.36  ? 58  GLU E CB  1 
ATOM   5857 C  CG  . GLU E 1 58  ? 41.258  -48.964 33.587  1.00 54.63  ? 58  GLU E CG  1 
ATOM   5858 C  CD  . GLU E 1 58  ? 41.261  -50.323 34.284  1.00 70.00  ? 58  GLU E CD  1 
ATOM   5859 O  OE1 . GLU E 1 58  ? 41.723  -50.411 35.450  1.00 76.23  ? 58  GLU E OE1 1 
ATOM   5860 O  OE2 . GLU E 1 58  ? 40.777  -51.302 33.665  1.00 81.77  ? 58  GLU E OE2 1 
ATOM   5861 N  N   . GLU E 1 59  ? 38.927  -45.384 35.244  1.00 37.78  ? 59  GLU E N   1 
ATOM   5862 C  CA  . GLU E 1 59  ? 37.763  -44.711 35.812  1.00 43.38  ? 59  GLU E CA  1 
ATOM   5863 C  C   . GLU E 1 59  ? 37.334  -43.533 34.942  1.00 44.23  ? 59  GLU E C   1 
ATOM   5864 O  O   . GLU E 1 59  ? 36.140  -43.352 34.670  1.00 36.61  ? 59  GLU E O   1 
ATOM   5865 C  CB  . GLU E 1 59  ? 38.055  -44.238 37.234  1.00 35.93  ? 59  GLU E CB  1 
ATOM   5866 C  CG  . GLU E 1 59  ? 38.250  -45.339 38.216  1.00 39.80  ? 59  GLU E CG  1 
ATOM   5867 C  CD  . GLU E 1 59  ? 37.134  -46.335 38.153  1.00 52.05  ? 59  GLU E CD  1 
ATOM   5868 O  OE1 . GLU E 1 59  ? 35.964  -45.905 38.144  1.00 51.75  ? 59  GLU E OE1 1 
ATOM   5869 O  OE2 . GLU E 1 59  ? 37.422  -47.546 38.101  1.00 57.96  ? 59  GLU E OE2 1 
ATOM   5870 N  N   . ARG E 1 60  ? 38.297  -42.726 34.491  1.00 34.96  ? 60  ARG E N   1 
ATOM   5871 C  CA  . ARG E 1 60  ? 37.963  -41.647 33.582  1.00 35.43  ? 60  ARG E CA  1 
ATOM   5872 C  C   . ARG E 1 60  ? 37.271  -42.185 32.340  1.00 42.90  ? 60  ARG E C   1 
ATOM   5873 O  O   . ARG E 1 60  ? 36.328  -41.562 31.846  1.00 41.68  ? 60  ARG E O   1 
ATOM   5874 C  CB  . ARG E 1 60  ? 39.219  -40.850 33.229  1.00 32.76  ? 60  ARG E CB  1 
ATOM   5875 C  CG  . ARG E 1 60  ? 38.940  -39.548 32.504  1.00 40.07  ? 60  ARG E CG  1 
ATOM   5876 C  CD  . ARG E 1 60  ? 40.210  -38.817 32.032  1.00 44.26  ? 60  ARG E CD  1 
ATOM   5877 N  NE  . ARG E 1 60  ? 39.865  -37.646 31.215  1.00 47.27  ? 60  ARG E NE  1 
ATOM   5878 C  CZ  . ARG E 1 60  ? 40.656  -37.120 30.273  1.00 49.24  ? 60  ARG E CZ  1 
ATOM   5879 N  NH1 . ARG E 1 60  ? 40.267  -36.062 29.552  1.00 33.05  ? 60  ARG E NH1 1 
ATOM   5880 N  NH2 . ARG E 1 60  ? 41.848  -37.664 30.042  1.00 55.03  ? 60  ARG E NH2 1 
ATOM   5881 N  N   . GLU E 1 61  ? 37.678  -43.369 31.862  1.00 42.96  ? 61  GLU E N   1 
ATOM   5882 C  CA  . GLU E 1 61  ? 37.027  -43.965 30.700  1.00 43.77  ? 61  GLU E CA  1 
ATOM   5883 C  C   . GLU E 1 61  ? 35.598  -44.399 31.011  1.00 42.06  ? 61  GLU E C   1 
ATOM   5884 O  O   . GLU E 1 61  ? 34.699  -44.198 30.188  1.00 45.99  ? 61  GLU E O   1 
ATOM   5885 C  CB  . GLU E 1 61  ? 37.842  -45.152 30.178  1.00 45.87  ? 61  GLU E CB  1 
ATOM   5886 C  CG  . GLU E 1 61  ? 39.062  -44.762 29.353  1.00 47.54  ? 61  GLU E CG  1 
ATOM   5887 C  CD  . GLU E 1 61  ? 38.711  -43.945 28.121  1.00 61.76  ? 61  GLU E CD  1 
ATOM   5888 O  OE1 . GLU E 1 61  ? 37.689  -44.251 27.459  1.00 63.94  ? 61  GLU E OE1 1 
ATOM   5889 O  OE2 . GLU E 1 61  ? 39.448  -42.973 27.829  1.00 66.40  ? 61  GLU E OE2 1 
ATOM   5890 N  N   . HIS E 1 62  ? 35.367  -45.020 32.175  1.00 40.18  ? 62  HIS E N   1 
ATOM   5891 C  CA  . HIS E 1 62  ? 34.001  -45.368 32.563  1.00 45.51  ? 62  HIS E CA  1 
ATOM   5892 C  C   . HIS E 1 62  ? 33.100  -44.136 32.569  1.00 48.55  ? 62  HIS E C   1 
ATOM   5893 O  O   . HIS E 1 62  ? 31.953  -44.196 32.097  1.00 45.22  ? 62  HIS E O   1 
ATOM   5894 C  CB  . HIS E 1 62  ? 33.977  -46.032 33.941  1.00 48.40  ? 62  HIS E CB  1 
ATOM   5895 C  CG  . HIS E 1 62  ? 34.432  -47.458 33.944  1.00 58.92  ? 62  HIS E CG  1 
ATOM   5896 N  ND1 . HIS E 1 62  ? 33.861  -48.427 33.148  1.00 71.38  ? 62  HIS E ND1 1 
ATOM   5897 C  CD2 . HIS E 1 62  ? 35.396  -48.083 34.664  1.00 59.89  ? 62  HIS E CD2 1 
ATOM   5898 C  CE1 . HIS E 1 62  ? 34.457  -49.586 33.373  1.00 72.01  ? 62  HIS E CE1 1 
ATOM   5899 N  NE2 . HIS E 1 62  ? 35.392  -49.405 34.287  1.00 61.43  ? 62  HIS E NE2 1 
ATOM   5900 N  N   . ALA E 1 63  ? 33.608  -43.007 33.096  1.00 38.26  ? 63  ALA E N   1 
ATOM   5901 C  CA  . ALA E 1 63  ? 32.824  -41.774 33.130  1.00 42.07  ? 63  ALA E CA  1 
ATOM   5902 C  C   . ALA E 1 63  ? 32.409  -41.347 31.723  1.00 41.88  ? 63  ALA E C   1 
ATOM   5903 O  O   . ALA E 1 63  ? 31.271  -40.915 31.503  1.00 41.75  ? 63  ALA E O   1 
ATOM   5904 C  CB  . ALA E 1 63  ? 33.610  -40.662 33.837  1.00 31.69  ? 63  ALA E CB  1 
ATOM   5905 N  N   . GLN E 1 64  ? 33.303  -41.489 30.751  1.00 37.52  ? 64  GLN E N   1 
ATOM   5906 C  CA  . GLN E 1 64  ? 32.948  -41.080 29.401  1.00 46.14  ? 64  GLN E CA  1 
ATOM   5907 C  C   . GLN E 1 64  ? 31.951  -42.041 28.781  1.00 44.12  ? 64  GLN E C   1 
ATOM   5908 O  O   . GLN E 1 64  ? 31.122  -41.637 27.959  1.00 42.55  ? 64  GLN E O   1 
ATOM   5909 C  CB  . GLN E 1 64  ? 34.207  -40.967 28.561  1.00 45.35  ? 64  GLN E CB  1 
ATOM   5910 C  CG  . GLN E 1 64  ? 34.998  -39.781 28.989  1.00 46.28  ? 64  GLN E CG  1 
ATOM   5911 C  CD  . GLN E 1 64  ? 36.336  -39.728 28.347  1.00 46.94  ? 64  GLN E CD  1 
ATOM   5912 O  OE1 . GLN E 1 64  ? 36.472  -39.366 27.173  1.00 53.89  ? 64  GLN E OE1 1 
ATOM   5913 N  NE2 . GLN E 1 64  ? 37.347  -40.089 29.109  1.00 44.10  ? 64  GLN E NE2 1 
ATOM   5914 N  N   . THR E 1 65  ? 32.001  -43.302 29.191  1.00 40.39  ? 65  THR E N   1 
ATOM   5915 C  CA  . THR E 1 65  ? 31.031  -44.278 28.719  1.00 45.37  ? 65  THR E CA  1 
ATOM   5916 C  C   . THR E 1 65  ? 29.616  -43.867 29.104  1.00 41.99  ? 65  THR E C   1 
ATOM   5917 O  O   . THR E 1 65  ? 28.708  -43.877 28.263  1.00 43.27  ? 65  THR E O   1 
ATOM   5918 C  CB  . THR E 1 65  ? 31.401  -45.641 29.295  1.00 48.05  ? 65  THR E CB  1 
ATOM   5919 O  OG1 . THR E 1 65  ? 32.669  -46.014 28.758  1.00 47.67  ? 65  THR E OG1 1 
ATOM   5920 C  CG2 . THR E 1 65  ? 30.351  -46.704 29.001  1.00 39.13  ? 65  THR E CG2 1 
ATOM   5921 N  N   . PHE E 1 66  ? 29.421  -43.467 30.361  1.00 40.53  ? 66  PHE E N   1 
ATOM   5922 C  CA  . PHE E 1 66  ? 28.128  -42.938 30.785  1.00 39.47  ? 66  PHE E CA  1 
ATOM   5923 C  C   . PHE E 1 66  ? 27.815  -41.596 30.128  1.00 41.12  ? 66  PHE E C   1 
ATOM   5924 O  O   . PHE E 1 66  ? 26.645  -41.318 29.840  1.00 39.36  ? 66  PHE E O   1 
ATOM   5925 C  CB  . PHE E 1 66  ? 28.101  -42.800 32.300  1.00 36.85  ? 66  PHE E CB  1 
ATOM   5926 C  CG  . PHE E 1 66  ? 28.055  -44.107 33.011  1.00 42.59  ? 66  PHE E CG  1 
ATOM   5927 C  CD1 . PHE E 1 66  ? 26.934  -44.919 32.922  1.00 44.68  ? 66  PHE E CD1 1 
ATOM   5928 C  CD2 . PHE E 1 66  ? 29.125  -44.532 33.776  1.00 43.91  ? 66  PHE E CD2 1 
ATOM   5929 C  CE1 . PHE E 1 66  ? 26.877  -46.133 33.595  1.00 53.50  ? 66  PHE E CE1 1 
ATOM   5930 C  CE2 . PHE E 1 66  ? 29.076  -45.756 34.451  1.00 51.64  ? 66  PHE E CE2 1 
ATOM   5931 C  CZ  . PHE E 1 66  ? 27.952  -46.554 34.356  1.00 52.15  ? 66  PHE E CZ  1 
ATOM   5932 N  N   . MET E 1 67  ? 28.828  -40.750 29.888  1.00 37.09  ? 67  MET E N   1 
ATOM   5933 C  CA  . MET E 1 67  ? 28.575  -39.521 29.132  1.00 44.15  ? 67  MET E CA  1 
ATOM   5934 C  C   . MET E 1 67  ? 28.056  -39.841 27.737  1.00 39.46  ? 67  MET E C   1 
ATOM   5935 O  O   . MET E 1 67  ? 27.054  -39.271 27.297  1.00 37.03  ? 67  MET E O   1 
ATOM   5936 C  CB  . MET E 1 67  ? 29.835  -38.652 29.050  1.00 36.53  ? 67  MET E CB  1 
ATOM   5937 C  CG  . MET E 1 67  ? 30.295  -38.188 30.417  1.00 40.41  ? 67  MET E CG  1 
ATOM   5938 S  SD  . MET E 1 67  ? 31.838  -37.272 30.386  1.00 34.53  ? 67  MET E SD  1 
ATOM   5939 C  CE  . MET E 1 67  ? 31.266  -35.761 29.599  1.00 41.66  ? 67  MET E CE  1 
ATOM   5940 N  N   . LYS E 1 68  ? 28.728  -40.760 27.030  1.00 41.99  ? 68  LYS E N   1 
ATOM   5941 C  CA  . LYS E 1 68  ? 28.284  -41.141 25.692  1.00 41.58  ? 68  LYS E CA  1 
ATOM   5942 C  C   . LYS E 1 68  ? 26.854  -41.651 25.732  1.00 40.87  ? 68  LYS E C   1 
ATOM   5943 O  O   . LYS E 1 68  ? 26.019  -41.249 24.910  1.00 37.66  ? 68  LYS E O   1 
ATOM   5944 C  CB  . LYS E 1 68  ? 29.217  -42.206 25.097  1.00 44.89  ? 68  LYS E CB  1 
ATOM   5945 C  CG  . LYS E 1 68  ? 30.505  -41.676 24.452  1.00 53.41  ? 68  LYS E CG  1 
ATOM   5946 C  CD  . LYS E 1 68  ? 31.413  -42.819 24.009  1.00 54.82  ? 68  LYS E CD  1 
ATOM   5947 C  CE  . LYS E 1 68  ? 32.454  -43.185 25.080  1.00 55.55  ? 68  LYS E CE  1 
ATOM   5948 N  NZ  . LYS E 1 68  ? 33.016  -44.584 24.943  1.00 53.09  ? 68  LYS E NZ  1 
ATOM   5949 N  N   . TYR E 1 69  ? 26.549  -42.502 26.720  1.00 39.48  ? 69  TYR E N   1 
ATOM   5950 C  CA  . TYR E 1 69  ? 25.216  -43.075 26.850  1.00 38.31  ? 69  TYR E CA  1 
ATOM   5951 C  C   . TYR E 1 69  ? 24.176  -41.995 27.108  1.00 45.36  ? 69  TYR E C   1 
ATOM   5952 O  O   . TYR E 1 69  ? 23.103  -41.993 26.493  1.00 46.82  ? 69  TYR E O   1 
ATOM   5953 C  CB  . TYR E 1 69  ? 25.183  -44.107 27.974  1.00 40.55  ? 69  TYR E CB  1 
ATOM   5954 C  CG  . TYR E 1 69  ? 23.863  -44.828 28.006  1.00 47.81  ? 69  TYR E CG  1 
ATOM   5955 C  CD1 . TYR E 1 69  ? 23.542  -45.726 27.008  1.00 51.95  ? 69  TYR E CD1 1 
ATOM   5956 C  CD2 . TYR E 1 69  ? 22.915  -44.570 28.988  1.00 47.00  ? 69  TYR E CD2 1 
ATOM   5957 C  CE1 . TYR E 1 69  ? 22.339  -46.373 26.991  1.00 51.52  ? 69  TYR E CE1 1 
ATOM   5958 C  CE2 . TYR E 1 69  ? 21.699  -45.222 28.982  1.00 57.02  ? 69  TYR E CE2 1 
ATOM   5959 C  CZ  . TYR E 1 69  ? 21.424  -46.129 27.968  1.00 55.78  ? 69  TYR E CZ  1 
ATOM   5960 O  OH  . TYR E 1 69  ? 20.232  -46.806 27.900  1.00 60.72  ? 69  TYR E OH  1 
ATOM   5961 N  N   . GLN E 1 70  ? 24.467  -41.079 28.036  1.00 45.78  ? 70  GLN E N   1 
ATOM   5962 C  CA  . GLN E 1 70  ? 23.598  -39.926 28.234  1.00 47.61  ? 70  GLN E CA  1 
ATOM   5963 C  C   . GLN E 1 70  ? 23.272  -39.242 26.906  1.00 45.09  ? 70  GLN E C   1 
ATOM   5964 O  O   . GLN E 1 70  ? 22.133  -38.831 26.666  1.00 43.11  ? 70  GLN E O   1 
ATOM   5965 C  CB  . GLN E 1 70  ? 24.258  -38.944 29.194  1.00 43.14  ? 70  GLN E CB  1 
ATOM   5966 C  CG  . GLN E 1 70  ? 23.385  -37.764 29.550  1.00 41.54  ? 70  GLN E CG  1 
ATOM   5967 C  CD  . GLN E 1 70  ? 22.474  -38.079 30.704  1.00 47.11  ? 70  GLN E CD  1 
ATOM   5968 O  OE1 . GLN E 1 70  ? 21.424  -38.701 30.521  1.00 50.13  ? 70  GLN E OE1 1 
ATOM   5969 N  NE2 . GLN E 1 70  ? 22.871  -37.668 31.910  1.00 38.19  ? 70  GLN E NE2 1 
ATOM   5970 N  N   . ASN E 1 71  ? 24.259  -39.137 26.013  1.00 45.16  ? 71  ASN E N   1 
ATOM   5971 C  CA  . ASN E 1 71  ? 24.011  -38.485 24.730  1.00 41.11  ? 71  ASN E CA  1 
ATOM   5972 C  C   . ASN E 1 71  ? 23.165  -39.378 23.832  1.00 48.22  ? 71  ASN E C   1 
ATOM   5973 O  O   . ASN E 1 71  ? 22.273  -38.895 23.115  1.00 45.61  ? 71  ASN E O   1 
ATOM   5974 C  CB  . ASN E 1 71  ? 25.341  -38.131 24.068  1.00 41.32  ? 71  ASN E CB  1 
ATOM   5975 C  CG  . ASN E 1 71  ? 25.811  -36.738 24.461  1.00 40.49  ? 71  ASN E CG  1 
ATOM   5976 O  OD1 . ASN E 1 71  ? 25.014  -35.939 24.943  1.00 44.49  ? 71  ASN E OD1 1 
ATOM   5977 N  ND2 . ASN E 1 71  ? 27.081  -36.442 24.272  1.00 39.40  ? 71  ASN E ND2 1 
ATOM   5978 N  N   . CYS E 1 72  ? 23.412  -40.697 23.910  1.00 46.62  ? 72  CYS E N   1 
ATOM   5979 C  CA  . CYS E 1 72  ? 22.640  -41.697 23.164  1.00 55.70  ? 72  CYS E CA  1 
ATOM   5980 C  C   . CYS E 1 72  ? 21.147  -41.434 23.299  1.00 53.49  ? 72  CYS E C   1 
ATOM   5981 O  O   . CYS E 1 72  ? 20.471  -41.089 22.323  1.00 65.80  ? 72  CYS E O   1 
ATOM   5982 C  CB  . CYS E 1 72  ? 22.941  -43.111 23.679  1.00 64.71  ? 72  CYS E CB  1 
ATOM   5983 S  SG  . CYS E 1 72  ? 22.634  -44.464 22.548  1.00 82.98  ? 72  CYS E SG  1 
ATOM   5984 N  N   . ARG E 1 73  ? 20.648  -41.486 24.535  1.00 45.83  ? 73  ARG E N   1 
ATOM   5985 C  CA  . ARG E 1 73  ? 19.247  -41.336 24.906  1.00 53.05  ? 73  ARG E CA  1 
ATOM   5986 C  C   . ARG E 1 73  ? 18.761  -39.886 24.861  1.00 50.15  ? 73  ARG E C   1 
ATOM   5987 O  O   . ARG E 1 73  ? 17.649  -39.593 25.323  1.00 62.00  ? 73  ARG E O   1 
ATOM   5988 C  CB  . ARG E 1 73  ? 19.045  -41.928 26.304  1.00 55.24  ? 73  ARG E CB  1 
ATOM   5989 C  CG  . ARG E 1 73  ? 19.772  -43.269 26.467  1.00 52.85  ? 73  ARG E CG  1 
ATOM   5990 C  CD  . ARG E 1 73  ? 19.151  -44.379 25.578  1.00 57.59  ? 73  ARG E CD  1 
ATOM   5991 N  NE  . ARG E 1 73  ? 17.687  -44.458 25.683  1.00 69.00  ? 73  ARG E NE  1 
ATOM   5992 C  CZ  . ARG E 1 73  ? 17.007  -45.247 26.517  1.00 62.91  ? 73  ARG E CZ  1 
ATOM   5993 N  NH1 . ARG E 1 73  ? 17.638  -46.074 27.339  1.00 69.34  ? 73  ARG E NH1 1 
ATOM   5994 N  NH2 . ARG E 1 73  ? 15.683  -45.214 26.525  1.00 64.01  ? 73  ARG E NH2 1 
ATOM   5995 N  N   . GLY E 1 74  ? 19.576  -38.978 24.328  1.00 48.46  ? 74  GLY E N   1 
ATOM   5996 C  CA  . GLY E 1 74  ? 19.216  -37.582 24.236  1.00 44.79  ? 74  GLY E CA  1 
ATOM   5997 C  C   . GLY E 1 74  ? 18.969  -36.902 25.560  1.00 55.69  ? 74  GLY E C   1 
ATOM   5998 O  O   . GLY E 1 74  ? 18.191  -35.943 25.610  1.00 51.71  ? 74  GLY E O   1 
ATOM   5999 N  N   . GLY E 1 75  ? 19.578  -37.400 26.646  1.00 45.78  ? 75  GLY E N   1 
ATOM   6000 C  CA  . GLY E 1 75  ? 19.651  -36.667 27.892  1.00 47.39  ? 75  GLY E CA  1 
ATOM   6001 C  C   . GLY E 1 75  ? 20.723  -35.583 27.845  1.00 52.41  ? 75  GLY E C   1 
ATOM   6002 O  O   . GLY E 1 75  ? 21.468  -35.430 26.873  1.00 50.98  ? 75  GLY E O   1 
ATOM   6003 N  N   . ARG E 1 76  ? 20.790  -34.807 28.921  1.00 42.25  ? 76  ARG E N   1 
ATOM   6004 C  CA  . ARG E 1 76  ? 21.729  -33.699 29.016  1.00 45.84  ? 76  ARG E CA  1 
ATOM   6005 C  C   . ARG E 1 76  ? 22.792  -34.029 30.055  1.00 49.31  ? 76  ARG E C   1 
ATOM   6006 O  O   . ARG E 1 76  ? 22.474  -34.228 31.237  1.00 43.19  ? 76  ARG E O   1 
ATOM   6007 C  CB  . ARG E 1 76  ? 21.030  -32.381 29.364  1.00 38.65  ? 76  ARG E CB  1 
ATOM   6008 C  CG  . ARG E 1 76  ? 20.456  -31.648 28.139  1.00 60.58  ? 76  ARG E CG  1 
ATOM   6009 C  CD  . ARG E 1 76  ? 21.149  -32.055 26.801  1.00 59.59  ? 76  ARG E CD  1 
ATOM   6010 N  NE  . ARG E 1 76  ? 20.543  -31.376 25.651  1.00 65.79  ? 76  ARG E NE  1 
ATOM   6011 C  CZ  . ARG E 1 76  ? 20.463  -31.874 24.417  1.00 64.82  ? 76  ARG E CZ  1 
ATOM   6012 N  NH1 . ARG E 1 76  ? 20.960  -33.078 24.134  1.00 62.14  ? 76  ARG E NH1 1 
ATOM   6013 N  NH2 . ARG E 1 76  ? 19.866  -31.163 23.466  1.00 67.12  ? 76  ARG E NH2 1 
ATOM   6014 N  N   . ILE E 1 77  ? 24.048  -34.105 29.606  1.00 36.94  ? 77  ILE E N   1 
ATOM   6015 C  CA  . ILE E 1 77  ? 25.151  -34.141 30.544  1.00 39.91  ? 77  ILE E CA  1 
ATOM   6016 C  C   . ILE E 1 77  ? 25.126  -32.851 31.347  1.00 38.40  ? 77  ILE E C   1 
ATOM   6017 O  O   . ILE E 1 77  ? 25.144  -31.749 30.787  1.00 36.10  ? 77  ILE E O   1 
ATOM   6018 C  CB  . ILE E 1 77  ? 26.485  -34.318 29.819  1.00 36.62  ? 77  ILE E CB  1 
ATOM   6019 C  CG1 . ILE E 1 77  ? 26.511  -35.657 29.082  1.00 34.54  ? 77  ILE E CG1 1 
ATOM   6020 C  CG2 . ILE E 1 77  ? 27.635  -34.241 30.817  1.00 36.40  ? 77  ILE E CG2 1 
ATOM   6021 C  CD1 . ILE E 1 77  ? 27.584  -35.735 28.020  1.00 30.25  ? 77  ILE E CD1 1 
ATOM   6022 N  N   . VAL E 1 78  ? 25.040  -32.984 32.658  1.00 33.46  ? 78  VAL E N   1 
ATOM   6023 C  CA  . VAL E 1 78  ? 25.253  -31.878 33.573  1.00 38.98  ? 78  VAL E CA  1 
ATOM   6024 C  C   . VAL E 1 78  ? 26.400  -32.291 34.485  1.00 37.46  ? 78  VAL E C   1 
ATOM   6025 O  O   . VAL E 1 78  ? 26.236  -33.172 35.345  1.00 31.58  ? 78  VAL E O   1 
ATOM   6026 C  CB  . VAL E 1 78  ? 23.992  -31.538 34.378  1.00 36.85  ? 78  VAL E CB  1 
ATOM   6027 C  CG1 . VAL E 1 78  ? 24.297  -30.383 35.319  1.00 27.88  ? 78  VAL E CG1 1 
ATOM   6028 C  CG2 . VAL E 1 78  ? 22.813  -31.226 33.424  1.00 27.61  ? 78  VAL E CG2 1 
ATOM   6029 N  N   . LEU E 1 79  ? 27.568  -31.691 34.265  1.00 31.19  ? 79  LEU E N   1 
ATOM   6030 C  CA  . LEU E 1 79  ? 28.757  -32.021 35.032  1.00 34.05  ? 79  LEU E CA  1 
ATOM   6031 C  C   . LEU E 1 79  ? 28.720  -31.302 36.382  1.00 34.92  ? 79  LEU E C   1 
ATOM   6032 O  O   . LEU E 1 79  ? 28.228  -30.180 36.492  1.00 35.00  ? 79  LEU E O   1 
ATOM   6033 C  CB  . LEU E 1 79  ? 30.024  -31.650 34.239  1.00 30.19  ? 79  LEU E CB  1 
ATOM   6034 C  CG  . LEU E 1 79  ? 30.325  -32.499 32.980  1.00 36.30  ? 79  LEU E CG  1 
ATOM   6035 C  CD1 . LEU E 1 79  ? 31.477  -31.929 32.138  1.00 28.65  ? 79  LEU E CD1 1 
ATOM   6036 C  CD2 . LEU E 1 79  ? 30.590  -33.986 33.322  1.00 26.26  ? 79  LEU E CD2 1 
ATOM   6037 N  N   . GLN E 1 80  ? 29.226  -31.968 37.415  1.00 36.10  ? 80  GLN E N   1 
ATOM   6038 C  CA  . GLN E 1 80  ? 29.278  -31.430 38.761  1.00 34.04  ? 80  GLN E CA  1 
ATOM   6039 C  C   . GLN E 1 80  ? 30.727  -31.371 39.217  1.00 35.10  ? 80  GLN E C   1 
ATOM   6040 O  O   . GLN E 1 80  ? 31.588  -32.069 38.677  1.00 35.27  ? 80  GLN E O   1 
ATOM   6041 C  CB  . GLN E 1 80  ? 28.459  -32.291 39.732  1.00 30.84  ? 80  GLN E CB  1 
ATOM   6042 C  CG  . GLN E 1 80  ? 26.946  -32.311 39.438  1.00 34.82  ? 80  GLN E CG  1 
ATOM   6043 C  CD  . GLN E 1 80  ? 26.240  -31.005 39.860  1.00 34.29  ? 80  GLN E CD  1 
ATOM   6044 O  OE1 . GLN E 1 80  ? 26.739  -30.238 40.707  1.00 32.27  ? 80  GLN E OE1 1 
ATOM   6045 N  NE2 . GLN E 1 80  ? 25.089  -30.752 39.264  1.00 27.89  ? 80  GLN E NE2 1 
ATOM   6046 N  N   . GLN E 1 81  ? 30.973  -30.537 40.230  1.00 32.02  ? 81  GLN E N   1 
ATOM   6047 C  CA  . GLN E 1 81  ? 32.293  -30.419 40.837  1.00 34.66  ? 81  GLN E CA  1 
ATOM   6048 C  C   . GLN E 1 81  ? 32.802  -31.774 41.300  1.00 30.70  ? 81  GLN E C   1 
ATOM   6049 O  O   . GLN E 1 81  ? 32.065  -32.572 41.878  1.00 33.86  ? 81  GLN E O   1 
ATOM   6050 C  CB  . GLN E 1 81  ? 32.235  -29.452 42.025  1.00 33.59  ? 81  GLN E CB  1 
ATOM   6051 C  CG  . GLN E 1 81  ? 33.496  -29.337 42.898  1.00 27.88  ? 81  GLN E CG  1 
ATOM   6052 C  CD  . GLN E 1 81  ? 33.404  -28.124 43.862  1.00 39.03  ? 81  GLN E CD  1 
ATOM   6053 O  OE1 . GLN E 1 81  ? 33.660  -26.974 43.463  1.00 38.50  ? 81  GLN E OE1 1 
ATOM   6054 N  NE2 . GLN E 1 81  ? 33.010  -28.380 45.118  1.00 31.21  ? 81  GLN E NE2 1 
ATOM   6055 N  N   . ILE E 1 82  ? 34.072  -32.032 41.034  1.00 34.05  ? 82  ILE E N   1 
ATOM   6056 C  CA  . ILE E 1 82  ? 34.723  -33.275 41.433  1.00 32.85  ? 82  ILE E CA  1 
ATOM   6057 C  C   . ILE E 1 82  ? 35.369  -33.013 42.788  1.00 31.59  ? 82  ILE E C   1 
ATOM   6058 O  O   . ILE E 1 82  ? 36.296  -32.206 42.891  1.00 38.58  ? 82  ILE E O   1 
ATOM   6059 C  CB  . ILE E 1 82  ? 35.755  -33.728 40.391  1.00 33.21  ? 82  ILE E CB  1 
ATOM   6060 C  CG1 . ILE E 1 82  ? 35.111  -33.808 38.998  1.00 34.11  ? 82  ILE E CG1 1 
ATOM   6061 C  CG2 . ILE E 1 82  ? 36.348  -35.096 40.746  1.00 33.22  ? 82  ILE E CG2 1 
ATOM   6062 C  CD1 . ILE E 1 82  ? 36.153  -33.836 37.871  1.00 31.55  ? 82  ILE E CD1 1 
ATOM   6063 N  N   . ALA E 1 83  ? 34.852  -33.660 43.833  1.00 29.75  ? 83  ALA E N   1 
ATOM   6064 C  CA  . ALA E 1 83  ? 35.348  -33.428 45.186  1.00 31.72  ? 83  ALA E CA  1 
ATOM   6065 C  C   . ALA E 1 83  ? 36.834  -33.763 45.292  1.00 39.15  ? 83  ALA E C   1 
ATOM   6066 O  O   . ALA E 1 83  ? 37.349  -34.659 44.608  1.00 34.91  ? 83  ALA E O   1 
ATOM   6067 C  CB  . ALA E 1 83  ? 34.567  -34.274 46.201  1.00 22.25  ? 83  ALA E CB  1 
ATOM   6068 N  N   . ALA E 1 84  ? 37.522  -33.019 46.151  1.00 34.17  ? 84  ALA E N   1 
ATOM   6069 C  CA  . ALA E 1 84  ? 38.854  -33.413 46.568  1.00 37.32  ? 84  ALA E CA  1 
ATOM   6070 C  C   . ALA E 1 84  ? 38.817  -34.821 47.147  1.00 45.51  ? 84  ALA E C   1 
ATOM   6071 O  O   . ALA E 1 84  ? 37.837  -35.198 47.812  1.00 47.36  ? 84  ALA E O   1 
ATOM   6072 C  CB  . ALA E 1 84  ? 39.413  -32.446 47.615  1.00 32.54  ? 84  ALA E CB  1 
ATOM   6073 N  N   . PRO E 1 85  ? 39.849  -35.629 46.906  1.00 43.66  ? 85  PRO E N   1 
ATOM   6074 C  CA  . PRO E 1 85  ? 39.948  -36.941 47.555  1.00 40.73  ? 85  PRO E CA  1 
ATOM   6075 C  C   . PRO E 1 85  ? 39.968  -36.812 49.067  1.00 50.04  ? 85  PRO E C   1 
ATOM   6076 O  O   . PRO E 1 85  ? 40.443  -35.812 49.621  1.00 43.67  ? 85  PRO E O   1 
ATOM   6077 C  CB  . PRO E 1 85  ? 41.279  -37.499 47.044  1.00 43.85  ? 85  PRO E CB  1 
ATOM   6078 C  CG  . PRO E 1 85  ? 41.592  -36.703 45.830  1.00 46.60  ? 85  PRO E CG  1 
ATOM   6079 C  CD  . PRO E 1 85  ? 40.992  -35.338 46.031  1.00 39.48  ? 85  PRO E CD  1 
ATOM   6080 N  N   . SER E 1 86  ? 39.476  -37.876 49.722  1.00 53.77  ? 86  SER E N   1 
ATOM   6081 C  CA  . SER E 1 86  ? 39.322  -37.914 51.177  1.00 57.66  ? 86  SER E CA  1 
ATOM   6082 C  C   . SER E 1 86  ? 40.623  -37.605 51.914  1.00 57.03  ? 86  SER E C   1 
ATOM   6083 O  O   . SER E 1 86  ? 40.592  -36.993 52.988  1.00 50.94  ? 86  SER E O   1 
ATOM   6084 C  CB  . SER E 1 86  ? 38.794  -39.283 51.601  1.00 56.84  ? 86  SER E CB  1 
ATOM   6085 O  OG  . SER E 1 86  ? 39.417  -40.312 50.842  1.00 63.37  ? 86  SER E OG  1 
ATOM   6086 N  N   . MET E 1 87  ? 41.773  -38.009 51.368  1.00 56.72  ? 87  MET E N   1 
ATOM   6087 C  CA  . MET E 1 87  ? 43.030  -37.550 51.938  1.00 56.84  ? 87  MET E CA  1 
ATOM   6088 C  C   . MET E 1 87  ? 44.104  -37.369 50.873  1.00 55.35  ? 87  MET E C   1 
ATOM   6089 O  O   . MET E 1 87  ? 43.880  -37.551 49.671  1.00 51.39  ? 87  MET E O   1 
ATOM   6090 C  CB  . MET E 1 87  ? 43.504  -38.493 53.022  1.00 61.44  ? 87  MET E CB  1 
ATOM   6091 C  CG  . MET E 1 87  ? 43.445  -39.930 52.641  1.00 59.55  ? 87  MET E CG  1 
ATOM   6092 S  SD  . MET E 1 87  ? 43.394  -40.770 54.228  1.00 83.18  ? 87  MET E SD  1 
ATOM   6093 C  CE  . MET E 1 87  ? 42.465  -39.562 55.191  1.00 53.01  ? 87  MET E CE  1 
ATOM   6094 N  N   . ARG E 1 88  ? 45.271  -36.937 51.350  1.00 53.13  ? 88  ARG E N   1 
ATOM   6095 C  CA  . ARG E 1 88  ? 46.476  -36.806 50.553  1.00 49.59  ? 88  ARG E CA  1 
ATOM   6096 C  C   . ARG E 1 88  ? 47.538  -37.837 50.850  1.00 47.60  ? 88  ARG E C   1 
ATOM   6097 O  O   . ARG E 1 88  ? 48.331  -38.138 49.959  1.00 61.06  ? 88  ARG E O   1 
ATOM   6098 C  CB  . ARG E 1 88  ? 47.120  -35.437 50.764  1.00 52.69  ? 88  ARG E CB  1 
ATOM   6099 C  CG  . ARG E 1 88  ? 46.193  -34.323 50.597  1.00 63.12  ? 88  ARG E CG  1 
ATOM   6100 C  CD  . ARG E 1 88  ? 46.198  -33.924 49.137  1.00 66.71  ? 88  ARG E CD  1 
ATOM   6101 N  NE  . ARG E 1 88  ? 44.947  -34.316 48.536  1.00 61.14  ? 88  ARG E NE  1 
ATOM   6102 C  CZ  . ARG E 1 88  ? 43.802  -33.754 48.878  1.00 59.67  ? 88  ARG E CZ  1 
ATOM   6103 N  NH1 . ARG E 1 88  ? 42.653  -34.132 48.310  1.00 65.78  ? 88  ARG E NH1 1 
ATOM   6104 N  NH2 . ARG E 1 88  ? 43.813  -32.803 49.806  1.00 61.26  ? 88  ARG E NH2 1 
ATOM   6105 N  N   . GLU E 1 89  ? 47.613  -38.341 52.075  1.00 48.96  ? 89  GLU E N   1 
ATOM   6106 C  CA  . GLU E 1 89  ? 48.607  -39.321 52.476  1.00 50.87  ? 89  GLU E CA  1 
ATOM   6107 C  C   . GLU E 1 89  ? 47.876  -40.648 52.588  1.00 50.40  ? 89  GLU E C   1 
ATOM   6108 O  O   . GLU E 1 89  ? 46.989  -40.808 53.432  1.00 48.70  ? 89  GLU E O   1 
ATOM   6109 C  CB  . GLU E 1 89  ? 49.255  -38.928 53.802  1.00 53.74  ? 89  GLU E CB  1 
ATOM   6110 C  CG  . GLU E 1 89  ? 49.905  -37.568 53.768  1.00 61.47  ? 89  GLU E CG  1 
ATOM   6111 C  CD  . GLU E 1 89  ? 50.843  -37.353 54.925  1.00 75.93  ? 89  GLU E CD  1 
ATOM   6112 O  OE1 . GLU E 1 89  ? 50.395  -36.838 55.976  1.00 80.18  ? 89  GLU E OE1 1 
ATOM   6113 O  OE2 . GLU E 1 89  ? 52.033  -37.709 54.780  1.00 82.95  ? 89  GLU E OE2 1 
ATOM   6114 N  N   . TRP E 1 90  ? 48.224  -41.592 51.736  1.00 40.67  ? 90  TRP E N   1 
ATOM   6115 C  CA  . TRP E 1 90  ? 47.465  -42.830 51.708  1.00 43.24  ? 90  TRP E CA  1 
ATOM   6116 C  C   . TRP E 1 90  ? 48.089  -43.920 52.566  1.00 41.71  ? 90  TRP E C   1 
ATOM   6117 O  O   . TRP E 1 90  ? 47.556  -45.028 52.605  1.00 46.56  ? 90  TRP E O   1 
ATOM   6118 C  CB  . TRP E 1 90  ? 47.280  -43.283 50.255  1.00 40.10  ? 90  TRP E CB  1 
ATOM   6119 C  CG  . TRP E 1 90  ? 46.483  -42.247 49.511  1.00 44.53  ? 90  TRP E CG  1 
ATOM   6120 C  CD1 . TRP E 1 90  ? 46.967  -41.228 48.731  1.00 42.05  ? 90  TRP E CD1 1 
ATOM   6121 C  CD2 . TRP E 1 90  ? 45.059  -42.093 49.534  1.00 44.31  ? 90  TRP E CD2 1 
ATOM   6122 N  NE1 . TRP E 1 90  ? 45.927  -40.466 48.259  1.00 43.97  ? 90  TRP E NE1 1 
ATOM   6123 C  CE2 . TRP E 1 90  ? 44.746  -40.979 48.733  1.00 44.41  ? 90  TRP E CE2 1 
ATOM   6124 C  CE3 . TRP E 1 90  ? 44.015  -42.812 50.134  1.00 45.84  ? 90  TRP E CE3 1 
ATOM   6125 C  CZ2 . TRP E 1 90  ? 43.425  -40.561 48.516  1.00 48.98  ? 90  TRP E CZ2 1 
ATOM   6126 C  CZ3 . TRP E 1 90  ? 42.707  -42.387 49.932  1.00 42.72  ? 90  TRP E CZ3 1 
ATOM   6127 C  CH2 . TRP E 1 90  ? 42.426  -41.270 49.128  1.00 46.32  ? 90  TRP E CH2 1 
ATOM   6128 N  N   . GLY E 1 91  ? 49.175  -43.619 53.285  1.00 41.47  ? 91  GLY E N   1 
ATOM   6129 C  CA  . GLY E 1 91  ? 49.766  -44.544 54.233  1.00 34.51  ? 91  GLY E CA  1 
ATOM   6130 C  C   . GLY E 1 91  ? 50.493  -45.712 53.591  1.00 42.04  ? 91  GLY E C   1 
ATOM   6131 O  O   . GLY E 1 91  ? 51.219  -45.537 52.606  1.00 41.17  ? 91  GLY E O   1 
ATOM   6132 N  N   . THR E 1 92  ? 50.300  -46.916 54.126  1.00 37.71  ? 92  THR E N   1 
ATOM   6133 C  CA  . THR E 1 92  ? 50.977  -48.062 53.549  1.00 42.81  ? 92  THR E CA  1 
ATOM   6134 C  C   . THR E 1 92  ? 50.300  -48.454 52.243  1.00 42.24  ? 92  THR E C   1 
ATOM   6135 O  O   . THR E 1 92  ? 49.167  -48.054 51.959  1.00 43.98  ? 92  THR E O   1 
ATOM   6136 C  CB  . THR E 1 92  ? 50.979  -49.257 54.511  1.00 43.17  ? 92  THR E CB  1 
ATOM   6137 O  OG1 . THR E 1 92  ? 49.647  -49.758 54.647  1.00 45.32  ? 92  THR E OG1 1 
ATOM   6138 C  CG2 . THR E 1 92  ? 51.512  -48.863 55.894  1.00 28.31  ? 92  THR E CG2 1 
ATOM   6139 N  N   . GLY E 1 93  ? 51.020  -49.238 51.435  1.00 35.28  ? 93  GLY E N   1 
ATOM   6140 C  CA  . GLY E 1 93  ? 50.409  -49.829 50.259  1.00 44.54  ? 93  GLY E CA  1 
ATOM   6141 C  C   . GLY E 1 93  ? 49.150  -50.617 50.577  1.00 45.63  ? 93  GLY E C   1 
ATOM   6142 O  O   . GLY E 1 93  ? 48.207  -50.634 49.778  1.00 46.98  ? 93  GLY E O   1 
ATOM   6143 N  N   . LEU E 1 94  ? 49.106  -51.259 51.750  1.00 43.92  ? 94  LEU E N   1 
ATOM   6144 C  CA  . LEU E 1 94  ? 47.934  -52.045 52.117  1.00 42.57  ? 94  LEU E CA  1 
ATOM   6145 C  C   . LEU E 1 94  ? 46.746  -51.135 52.414  1.00 44.91  ? 94  LEU E C   1 
ATOM   6146 O  O   . LEU E 1 94  ? 45.645  -51.337 51.881  1.00 43.68  ? 94  LEU E O   1 
ATOM   6147 C  CB  . LEU E 1 94  ? 48.259  -52.950 53.312  1.00 36.28  ? 94  LEU E CB  1 
ATOM   6148 C  CG  . LEU E 1 94  ? 47.064  -53.763 53.839  1.00 44.80  ? 94  LEU E CG  1 
ATOM   6149 C  CD1 . LEU E 1 94  ? 46.714  -54.882 52.869  1.00 40.34  ? 94  LEU E CD1 1 
ATOM   6150 C  CD2 . LEU E 1 94  ? 47.309  -54.332 55.230  1.00 40.45  ? 94  LEU E CD2 1 
ATOM   6151 N  N   . GLU E 1 95  ? 46.965  -50.109 53.247  1.00 44.44  ? 95  GLU E N   1 
ATOM   6152 C  CA  . GLU E 1 95  ? 45.940  -49.106 53.527  1.00 40.66  ? 95  GLU E CA  1 
ATOM   6153 C  C   . GLU E 1 95  ? 45.401  -48.481 52.248  1.00 39.70  ? 95  GLU E C   1 
ATOM   6154 O  O   . GLU E 1 95  ? 44.184  -48.333 52.080  1.00 37.78  ? 95  GLU E O   1 
ATOM   6155 C  CB  . GLU E 1 95  ? 46.519  -48.033 54.443  1.00 39.75  ? 95  GLU E CB  1 
ATOM   6156 C  CG  . GLU E 1 95  ? 46.701  -48.533 55.880  1.00 43.53  ? 95  GLU E CG  1 
ATOM   6157 C  CD  . GLU E 1 95  ? 47.547  -47.611 56.767  1.00 52.62  ? 95  GLU E CD  1 
ATOM   6158 O  OE1 . GLU E 1 95  ? 48.583  -47.087 56.292  1.00 55.14  ? 95  GLU E OE1 1 
ATOM   6159 O  OE2 . GLU E 1 95  ? 47.179  -47.424 57.951  1.00 59.01  ? 95  GLU E OE2 1 
ATOM   6160 N  N   . ALA E 1 96  ? 46.289  -48.134 51.320  1.00 38.01  ? 96  ALA E N   1 
ATOM   6161 C  CA  . ALA E 1 96  ? 45.833  -47.581 50.054  1.00 35.12  ? 96  ALA E CA  1 
ATOM   6162 C  C   . ALA E 1 96  ? 44.918  -48.558 49.330  1.00 40.56  ? 96  ALA E C   1 
ATOM   6163 O  O   . ALA E 1 96  ? 43.924  -48.147 48.719  1.00 38.93  ? 96  ALA E O   1 
ATOM   6164 C  CB  . ALA E 1 96  ? 47.029  -47.214 49.185  1.00 37.04  ? 96  ALA E CB  1 
ATOM   6165 N  N   . LEU E 1 97  ? 45.224  -49.860 49.408  1.00 39.72  ? 97  LEU E N   1 
ATOM   6166 C  CA  . LEU E 1 97  ? 44.423  -50.865 48.716  1.00 37.06  ? 97  LEU E CA  1 
ATOM   6167 C  C   . LEU E 1 97  ? 43.069  -51.055 49.382  1.00 41.93  ? 97  LEU E C   1 
ATOM   6168 O  O   . LEU E 1 97  ? 42.058  -51.222 48.687  1.00 37.85  ? 97  LEU E O   1 
ATOM   6169 C  CB  . LEU E 1 97  ? 45.163  -52.203 48.664  1.00 38.30  ? 97  LEU E CB  1 
ATOM   6170 C  CG  . LEU E 1 97  ? 46.375  -52.315 47.740  1.00 39.39  ? 97  LEU E CG  1 
ATOM   6171 C  CD1 . LEU E 1 97  ? 47.096  -53.617 47.999  1.00 40.11  ? 97  LEU E CD1 1 
ATOM   6172 C  CD2 . LEU E 1 97  ? 45.974  -52.195 46.259  1.00 39.04  ? 97  LEU E CD2 1 
ATOM   6173 N  N   . GLN E 1 98  ? 43.026  -51.055 50.724  1.00 39.18  ? 98  GLN E N   1 
ATOM   6174 C  CA  . GLN E 1 98  ? 41.734  -51.178 51.390  1.00 40.43  ? 98  GLN E CA  1 
ATOM   6175 C  C   . GLN E 1 98  ? 40.873  -49.949 51.153  1.00 43.15  ? 98  GLN E C   1 
ATOM   6176 O  O   . GLN E 1 98  ? 39.648  -50.076 51.042  1.00 42.64  ? 98  GLN E O   1 
ATOM   6177 C  CB  . GLN E 1 98  ? 41.899  -51.448 52.891  1.00 39.17  ? 98  GLN E CB  1 
ATOM   6178 C  CG  . GLN E 1 98  ? 42.766  -52.673 53.170  1.00 50.27  ? 98  GLN E CG  1 
ATOM   6179 C  CD  . GLN E 1 98  ? 43.162  -52.843 54.632  1.00 55.05  ? 98  GLN E CD  1 
ATOM   6180 O  OE1 . GLN E 1 98  ? 43.877  -52.010 55.203  1.00 52.09  ? 98  GLN E OE1 1 
ATOM   6181 N  NE2 . GLN E 1 98  ? 42.727  -53.952 55.234  1.00 56.17  ? 98  GLN E NE2 1 
ATOM   6182 N  N   . ALA E 1 99  ? 41.495  -48.763 51.053  1.00 39.82  ? 99  ALA E N   1 
ATOM   6183 C  CA  . ALA E 1 99  ? 40.766  -47.564 50.649  1.00 36.84  ? 99  ALA E CA  1 
ATOM   6184 C  C   . ALA E 1 99  ? 40.249  -47.692 49.225  1.00 41.93  ? 99  ALA E C   1 
ATOM   6185 O  O   . ALA E 1 99  ? 39.125  -47.267 48.924  1.00 38.68  ? 99  ALA E O   1 
ATOM   6186 C  CB  . ALA E 1 99  ? 41.653  -46.330 50.759  1.00 32.81  ? 99  ALA E CB  1 
ATOM   6187 N  N   . ALA E 1 100 ? 41.059  -48.270 48.335  1.00 36.87  ? 100 ALA E N   1 
ATOM   6188 C  CA  . ALA E 1 100 ? 40.604  -48.486 46.969  1.00 43.08  ? 100 ALA E CA  1 
ATOM   6189 C  C   . ALA E 1 100 ? 39.436  -49.462 46.935  1.00 45.34  ? 100 ALA E C   1 
ATOM   6190 O  O   . ALA E 1 100 ? 38.444  -49.222 46.234  1.00 46.55  ? 100 ALA E O   1 
ATOM   6191 C  CB  . ALA E 1 100 ? 41.758  -48.980 46.093  1.00 37.23  ? 100 ALA E CB  1 
ATOM   6192 N  N   . LEU E 1 101 ? 39.521  -50.555 47.700  1.00 41.23  ? 101 LEU E N   1 
ATOM   6193 C  CA  . LEU E 1 101 ? 38.410  -51.502 47.747  1.00 43.40  ? 101 LEU E CA  1 
ATOM   6194 C  C   . LEU E 1 101 ? 37.128  -50.808 48.194  1.00 48.66  ? 101 LEU E C   1 
ATOM   6195 O  O   . LEU E 1 101 ? 36.082  -50.940 47.551  1.00 50.99  ? 101 LEU E O   1 
ATOM   6196 C  CB  . LEU E 1 101 ? 38.747  -52.676 48.671  1.00 47.31  ? 101 LEU E CB  1 
ATOM   6197 C  CG  . LEU E 1 101 ? 37.667  -53.760 48.787  1.00 48.97  ? 101 LEU E CG  1 
ATOM   6198 C  CD1 . LEU E 1 101 ? 37.408  -54.394 47.438  1.00 48.59  ? 101 LEU E CD1 1 
ATOM   6199 C  CD2 . LEU E 1 101 ? 38.062  -54.814 49.798  1.00 47.19  ? 101 LEU E CD2 1 
ATOM   6200 N  N   . ASP E 1 102 ? 37.203  -50.036 49.280  1.00 46.61  ? 102 ASP E N   1 
ATOM   6201 C  CA  . ASP E 1 102 ? 36.070  -49.228 49.717  1.00 46.03  ? 102 ASP E CA  1 
ATOM   6202 C  C   . ASP E 1 102 ? 35.563  -48.325 48.602  1.00 49.80  ? 102 ASP E C   1 
ATOM   6203 O  O   . ASP E 1 102 ? 34.354  -48.273 48.333  1.00 49.64  ? 102 ASP E O   1 
ATOM   6204 C  CB  . ASP E 1 102 ? 36.467  -48.381 50.921  1.00 46.21  ? 102 ASP E CB  1 
ATOM   6205 C  CG  . ASP E 1 102 ? 36.636  -49.198 52.167  1.00 56.53  ? 102 ASP E CG  1 
ATOM   6206 O  OD1 . ASP E 1 102 ? 36.517  -50.442 52.088  1.00 58.65  ? 102 ASP E OD1 1 
ATOM   6207 O  OD2 . ASP E 1 102 ? 36.873  -48.594 53.234  1.00 72.12  ? 102 ASP E OD2 1 
ATOM   6208 N  N   . LEU E 1 103 ? 36.477  -47.589 47.954  1.00 40.72  ? 103 LEU E N   1 
ATOM   6209 C  CA  . LEU E 1 103 ? 36.074  -46.676 46.887  1.00 41.77  ? 103 LEU E CA  1 
ATOM   6210 C  C   . LEU E 1 103 ? 35.358  -47.425 45.773  1.00 44.12  ? 103 LEU E C   1 
ATOM   6211 O  O   . LEU E 1 103 ? 34.334  -46.962 45.272  1.00 45.87  ? 103 LEU E O   1 
ATOM   6212 C  CB  . LEU E 1 103 ? 37.292  -45.921 46.341  1.00 40.69  ? 103 LEU E CB  1 
ATOM   6213 C  CG  . LEU E 1 103 ? 37.040  -45.012 45.142  1.00 39.73  ? 103 LEU E CG  1 
ATOM   6214 C  CD1 . LEU E 1 103 ? 36.173  -43.819 45.531  1.00 40.28  ? 103 LEU E CD1 1 
ATOM   6215 C  CD2 . LEU E 1 103 ? 38.338  -44.557 44.512  1.00 41.32  ? 103 LEU E CD2 1 
ATOM   6216 N  N   . GLU E 1 104 ? 35.860  -48.605 45.400  1.00 47.90  ? 104 GLU E N   1 
ATOM   6217 C  CA  . GLU E 1 104 ? 35.217  -49.400 44.356  1.00 50.30  ? 104 GLU E CA  1 
ATOM   6218 C  C   . GLU E 1 104 ? 33.832  -49.863 44.787  1.00 51.62  ? 104 GLU E C   1 
ATOM   6219 O  O   . GLU E 1 104 ? 32.876  -49.813 44.007  1.00 48.99  ? 104 GLU E O   1 
ATOM   6220 C  CB  . GLU E 1 104 ? 36.082  -50.611 43.999  1.00 49.49  ? 104 GLU E CB  1 
ATOM   6221 C  CG  . GLU E 1 104 ? 37.396  -50.276 43.299  1.00 58.01  ? 104 GLU E CG  1 
ATOM   6222 C  CD  . GLU E 1 104 ? 37.213  -49.821 41.861  1.00 62.26  ? 104 GLU E CD  1 
ATOM   6223 O  OE1 . GLU E 1 104 ? 36.186  -50.185 41.251  1.00 73.05  ? 104 GLU E OE1 1 
ATOM   6224 O  OE2 . GLU E 1 104 ? 38.095  -49.103 41.343  1.00 55.73  ? 104 GLU E OE2 1 
ATOM   6225 N  N   . LYS E 1 105 ? 33.712  -50.349 46.021  1.00 56.64  ? 105 LYS E N   1 
ATOM   6226 C  CA  . LYS E 1 105 ? 32.405  -50.771 46.505  1.00 57.76  ? 105 LYS E CA  1 
ATOM   6227 C  C   . LYS E 1 105 ? 31.438  -49.599 46.534  1.00 56.18  ? 105 LYS E C   1 
ATOM   6228 O  O   . LYS E 1 105 ? 30.250  -49.763 46.242  1.00 61.91  ? 105 LYS E O   1 
ATOM   6229 C  CB  . LYS E 1 105 ? 32.535  -51.408 47.883  1.00 53.89  ? 105 LYS E CB  1 
ATOM   6230 C  CG  . LYS E 1 105 ? 33.050  -52.839 47.835  1.00 57.45  ? 105 LYS E CG  1 
ATOM   6231 C  CD  . LYS E 1 105 ? 33.384  -53.331 49.228  1.00 59.96  ? 105 LYS E CD  1 
ATOM   6232 C  CE  . LYS E 1 105 ? 33.726  -54.806 49.236  1.00 65.59  ? 105 LYS E CE  1 
ATOM   6233 N  NZ  . LYS E 1 105 ? 33.979  -55.227 50.638  1.00 73.85  ? 105 LYS E NZ  1 
ATOM   6234 N  N   . GLN E 1 106 ? 31.937  -48.402 46.842  1.00 51.42  ? 106 GLN E N   1 
ATOM   6235 C  CA  . GLN E 1 106 ? 31.075  -47.231 46.895  1.00 45.80  ? 106 GLN E CA  1 
ATOM   6236 C  C   . GLN E 1 106 ? 30.527  -46.888 45.514  1.00 55.60  ? 106 GLN E C   1 
ATOM   6237 O  O   . GLN E 1 106 ? 29.314  -46.723 45.344  1.00 57.12  ? 106 GLN E O   1 
ATOM   6238 C  CB  . GLN E 1 106 ? 31.834  -46.048 47.491  1.00 46.69  ? 106 GLN E CB  1 
ATOM   6239 C  CG  . GLN E 1 106 ? 30.912  -44.931 47.901  1.00 65.26  ? 106 GLN E CG  1 
ATOM   6240 C  CD  . GLN E 1 106 ? 31.539  -43.551 47.808  1.00 72.60  ? 106 GLN E CD  1 
ATOM   6241 O  OE1 . GLN E 1 106 ? 32.765  -43.401 47.845  1.00 68.29  ? 106 GLN E OE1 1 
ATOM   6242 N  NE2 . GLN E 1 106 ? 30.690  -42.526 47.696  1.00 67.49  ? 106 GLN E NE2 1 
ATOM   6243 N  N   . VAL E 1 107 ? 31.412  -46.782 44.511  1.00 57.63  ? 107 VAL E N   1 
ATOM   6244 C  CA  . VAL E 1 107 ? 30.990  -46.541 43.127  1.00 56.05  ? 107 VAL E CA  1 
ATOM   6245 C  C   . VAL E 1 107 ? 30.018  -47.627 42.656  1.00 60.15  ? 107 VAL E C   1 
ATOM   6246 O  O   . VAL E 1 107 ? 29.011  -47.343 41.991  1.00 55.25  ? 107 VAL E O   1 
ATOM   6247 C  CB  . VAL E 1 107 ? 32.227  -46.448 42.209  1.00 50.13  ? 107 VAL E CB  1 
ATOM   6248 C  CG1 . VAL E 1 107 ? 31.821  -46.416 40.737  1.00 46.67  ? 107 VAL E CG1 1 
ATOM   6249 C  CG2 . VAL E 1 107 ? 33.049  -45.221 42.546  1.00 43.15  ? 107 VAL E CG2 1 
ATOM   6250 N  N   . ASN E 1 108 ? 30.299  -48.885 43.004  1.00 56.51  ? 108 ASN E N   1 
ATOM   6251 C  CA  . ASN E 1 108 ? 29.440  -49.993 42.601  1.00 57.90  ? 108 ASN E CA  1 
ATOM   6252 C  C   . ASN E 1 108 ? 28.095  -49.954 43.304  1.00 63.84  ? 108 ASN E C   1 
ATOM   6253 O  O   . ASN E 1 108 ? 27.087  -50.400 42.743  1.00 60.47  ? 108 ASN E O   1 
ATOM   6254 C  CB  . ASN E 1 108 ? 30.140  -51.306 42.903  1.00 63.85  ? 108 ASN E CB  1 
ATOM   6255 C  CG  . ASN E 1 108 ? 30.964  -51.786 41.754  1.00 73.52  ? 108 ASN E CG  1 
ATOM   6256 O  OD1 . ASN E 1 108 ? 31.805  -51.056 41.215  1.00 74.04  ? 108 ASN E OD1 1 
ATOM   6257 N  ND2 . ASN E 1 108 ? 30.741  -53.030 41.370  1.00 83.66  ? 108 ASN E ND2 1 
ATOM   6258 N  N   . GLN E 1 109 ? 28.079  -49.472 44.547  1.00 66.15  ? 109 GLN E N   1 
ATOM   6259 C  CA  . GLN E 1 109 ? 26.829  -49.237 45.257  1.00 61.02  ? 109 GLN E CA  1 
ATOM   6260 C  C   . GLN E 1 109 ? 25.933  -48.289 44.472  1.00 61.97  ? 109 GLN E C   1 
ATOM   6261 O  O   . GLN E 1 109 ? 24.732  -48.536 44.311  1.00 58.45  ? 109 GLN E O   1 
ATOM   6262 C  CB  . GLN E 1 109 ? 27.129  -48.670 46.646  1.00 56.03  ? 109 GLN E CB  1 
ATOM   6263 C  CG  . GLN E 1 109 ? 25.929  -48.605 47.549  1.00 64.56  ? 109 GLN E CG  1 
ATOM   6264 C  CD  . GLN E 1 109 ? 25.106  -49.875 47.473  1.00 69.91  ? 109 GLN E CD  1 
ATOM   6265 O  OE1 . GLN E 1 109 ? 25.625  -50.984 47.640  1.00 70.62  ? 109 GLN E OE1 1 
ATOM   6266 N  NE2 . GLN E 1 109 ? 23.815  -49.721 47.202  1.00 68.23  ? 109 GLN E NE2 1 
ATOM   6267 N  N   . SER E 1 110 ? 26.512  -47.201 43.962  1.00 55.72  ? 110 SER E N   1 
ATOM   6268 C  CA  . SER E 1 110 ? 25.722  -46.217 43.239  1.00 54.84  ? 110 SER E CA  1 
ATOM   6269 C  C   . SER E 1 110 ? 25.181  -46.794 41.934  1.00 59.38  ? 110 SER E C   1 
ATOM   6270 O  O   . SER E 1 110 ? 24.062  -46.460 41.522  1.00 59.14  ? 110 SER E O   1 
ATOM   6271 C  CB  . SER E 1 110 ? 26.576  -44.970 43.014  1.00 51.40  ? 110 SER E CB  1 
ATOM   6272 O  OG  . SER E 1 110 ? 26.119  -44.206 41.927  1.00 55.51  ? 110 SER E OG  1 
ATOM   6273 N  N   . LEU E 1 111 ? 25.944  -47.684 41.293  1.00 57.69  ? 111 LEU E N   1 
ATOM   6274 C  CA  . LEU E 1 111 ? 25.455  -48.397 40.116  1.00 56.30  ? 111 LEU E CA  1 
ATOM   6275 C  C   . LEU E 1 111 ? 24.212  -49.220 40.431  1.00 59.10  ? 111 LEU E C   1 
ATOM   6276 O  O   . LEU E 1 111 ? 23.302  -49.321 39.601  1.00 59.26  ? 111 LEU E O   1 
ATOM   6277 C  CB  . LEU E 1 111 ? 26.548  -49.318 39.578  1.00 55.34  ? 111 LEU E CB  1 
ATOM   6278 C  CG  . LEU E 1 111 ? 27.521  -48.728 38.576  1.00 56.69  ? 111 LEU E CG  1 
ATOM   6279 C  CD1 . LEU E 1 111 ? 28.648  -49.717 38.322  1.00 69.47  ? 111 LEU E CD1 1 
ATOM   6280 C  CD2 . LEU E 1 111 ? 26.784  -48.381 37.292  1.00 57.21  ? 111 LEU E CD2 1 
ATOM   6281 N  N   . LEU E 1 112 ? 24.180  -49.851 41.609  1.00 55.87  ? 112 LEU E N   1 
ATOM   6282 C  CA  . LEU E 1 112 ? 23.044  -50.684 41.998  1.00 62.05  ? 112 LEU E CA  1 
ATOM   6283 C  C   . LEU E 1 112 ? 21.778  -49.859 42.159  1.00 60.01  ? 112 LEU E C   1 
ATOM   6284 O  O   . LEU E 1 112 ? 20.711  -50.248 41.671  1.00 62.99  ? 112 LEU E O   1 
ATOM   6285 C  CB  . LEU E 1 112 ? 23.352  -51.428 43.298  1.00 60.97  ? 112 LEU E CB  1 
ATOM   6286 C  CG  . LEU E 1 112 ? 23.634  -52.904 43.082  1.00 69.15  ? 112 LEU E CG  1 
ATOM   6287 C  CD1 . LEU E 1 112 ? 22.387  -53.660 42.719  1.00 70.07  ? 112 LEU E CD1 1 
ATOM   6288 C  CD2 . LEU E 1 112 ? 24.554  -52.940 41.933  1.00 72.78  ? 112 LEU E CD2 1 
ATOM   6289 N  N   . GLU E 1 113 ? 21.876  -48.730 42.874  1.00 58.72  ? 113 GLU E N   1 
ATOM   6290 C  CA  . GLU E 1 113 ? 20.738  -47.833 43.028  1.00 59.34  ? 113 GLU E CA  1 
ATOM   6291 C  C   . GLU E 1 113 ? 20.238  -47.371 41.670  1.00 65.99  ? 113 GLU E C   1 
ATOM   6292 O  O   . GLU E 1 113 ? 19.027  -47.352 41.409  1.00 69.77  ? 113 GLU E O   1 
ATOM   6293 C  CB  . GLU E 1 113 ? 21.127  -46.641 43.905  1.00 55.95  ? 113 GLU E CB  1 
ATOM   6294 C  CG  . GLU E 1 113 ? 21.747  -47.037 45.248  1.00 60.38  ? 113 GLU E CG  1 
ATOM   6295 C  CD  . GLU E 1 113 ? 22.571  -45.920 45.904  1.00 65.66  ? 113 GLU E CD  1 
ATOM   6296 O  OE1 . GLU E 1 113 ? 22.774  -44.845 45.283  1.00 69.71  ? 113 GLU E OE1 1 
ATOM   6297 O  OE2 . GLU E 1 113 ? 23.003  -46.123 47.059  1.00 65.65  ? 113 GLU E OE2 1 
ATOM   6298 N  N   . LEU E 1 114 ? 21.167  -47.027 40.781  1.00 62.69  ? 114 LEU E N   1 
ATOM   6299 C  CA  . LEU E 1 114 ? 20.811  -46.738 39.402  1.00 62.73  ? 114 LEU E CA  1 
ATOM   6300 C  C   . LEU E 1 114 ? 20.180  -47.948 38.721  1.00 67.20  ? 114 LEU E C   1 
ATOM   6301 O  O   . LEU E 1 114 ? 19.237  -47.804 37.936  1.00 71.18  ? 114 LEU E O   1 
ATOM   6302 C  CB  . LEU E 1 114 ? 22.059  -46.258 38.672  1.00 54.50  ? 114 LEU E CB  1 
ATOM   6303 C  CG  . LEU E 1 114 ? 22.041  -45.916 37.196  1.00 60.84  ? 114 LEU E CG  1 
ATOM   6304 C  CD1 . LEU E 1 114 ? 20.850  -45.048 36.833  1.00 59.05  ? 114 LEU E CD1 1 
ATOM   6305 C  CD2 . LEU E 1 114 ? 23.352  -45.198 36.867  1.00 54.06  ? 114 LEU E CD2 1 
ATOM   6306 N  N   . HIS E 1 115 ? 20.662  -49.154 39.027  1.00 68.00  ? 115 HIS E N   1 
ATOM   6307 C  CA  . HIS E 1 115 ? 20.087  -50.341 38.399  1.00 66.59  ? 115 HIS E CA  1 
ATOM   6308 C  C   . HIS E 1 115 ? 18.622  -50.517 38.783  1.00 69.22  ? 115 HIS E C   1 
ATOM   6309 O  O   . HIS E 1 115 ? 17.770  -50.740 37.916  1.00 74.41  ? 115 HIS E O   1 
ATOM   6310 C  CB  . HIS E 1 115 ? 20.883  -51.589 38.763  1.00 59.20  ? 115 HIS E CB  1 
ATOM   6311 C  CG  . HIS E 1 115 ? 20.353  -52.834 38.125  1.00 66.50  ? 115 HIS E CG  1 
ATOM   6312 N  ND1 . HIS E 1 115 ? 19.458  -53.673 38.757  1.00 65.76  ? 115 HIS E ND1 1 
ATOM   6313 C  CD2 . HIS E 1 115 ? 20.572  -53.369 36.900  1.00 71.11  ? 115 HIS E CD2 1 
ATOM   6314 C  CE1 . HIS E 1 115 ? 19.158  -54.676 37.951  1.00 71.64  ? 115 HIS E CE1 1 
ATOM   6315 N  NE2 . HIS E 1 115 ? 19.824  -54.518 36.820  1.00 70.16  ? 115 HIS E NE2 1 
ATOM   6316 N  N   . SER E 1 116 ? 18.310  -50.430 40.079  1.00 65.18  ? 116 SER E N   1 
ATOM   6317 C  CA  . SER E 1 116 ? 16.915  -50.527 40.507  1.00 68.73  ? 116 SER E CA  1 
ATOM   6318 C  C   . SER E 1 116 ? 16.069  -49.425 39.878  1.00 73.15  ? 116 SER E C   1 
ATOM   6319 O  O   . SER E 1 116 ? 14.983  -49.683 39.345  1.00 68.89  ? 116 SER E O   1 
ATOM   6320 C  CB  . SER E 1 116 ? 16.829  -50.468 42.032  1.00 64.09  ? 116 SER E CB  1 
ATOM   6321 O  OG  . SER E 1 116 ? 17.385  -51.633 42.623  1.00 78.46  ? 116 SER E OG  1 
ATOM   6322 N  N   . THR E 1 117 ? 16.557  -48.183 39.935  1.00 74.35  ? 117 THR E N   1 
ATOM   6323 C  CA  . THR E 1 117 ? 15.863  -47.066 39.303  1.00 75.31  ? 117 THR E CA  1 
ATOM   6324 C  C   . THR E 1 117 ? 15.583  -47.362 37.830  1.00 74.35  ? 117 THR E C   1 
ATOM   6325 O  O   . THR E 1 117 ? 14.471  -47.136 37.338  1.00 75.05  ? 117 THR E O   1 
ATOM   6326 C  CB  . THR E 1 117 ? 16.702  -45.787 39.491  1.00 77.27  ? 117 THR E CB  1 
ATOM   6327 O  OG1 . THR E 1 117 ? 16.618  -45.359 40.860  1.00 72.31  ? 117 THR E OG1 1 
ATOM   6328 C  CG2 . THR E 1 117 ? 16.265  -44.634 38.552  1.00 62.86  ? 117 THR E CG2 1 
ATOM   6329 N  N   . ALA E 1 118 ? 16.566  -47.928 37.129  1.00 73.70  ? 118 ALA E N   1 
ATOM   6330 C  CA  . ALA E 1 118 ? 16.395  -48.257 35.717  1.00 71.55  ? 118 ALA E CA  1 
ATOM   6331 C  C   . ALA E 1 118 ? 15.420  -49.414 35.500  1.00 76.48  ? 118 ALA E C   1 
ATOM   6332 O  O   . ALA E 1 118 ? 14.746  -49.462 34.463  1.00 76.52  ? 118 ALA E O   1 
ATOM   6333 C  CB  . ALA E 1 118 ? 17.752  -48.579 35.100  1.00 69.74  ? 118 ALA E CB  1 
ATOM   6334 N  N   . SER E 1 119 ? 15.325  -50.352 36.449  1.00 79.10  ? 119 SER E N   1 
ATOM   6335 C  CA  . SER E 1 119 ? 14.370  -51.454 36.308  1.00 78.78  ? 119 SER E CA  1 
ATOM   6336 C  C   . SER E 1 119 ? 12.943  -51.010 36.641  1.00 82.36  ? 119 SER E C   1 
ATOM   6337 O  O   . SER E 1 119 ? 11.996  -51.362 35.924  1.00 87.37  ? 119 SER E O   1 
ATOM   6338 C  CB  . SER E 1 119 ? 14.800  -52.639 37.182  1.00 72.72  ? 119 SER E CB  1 
ATOM   6339 O  OG  . SER E 1 119 ? 14.083  -52.665 38.409  1.00 85.24  ? 119 SER E OG  1 
ATOM   6340 N  N   . GLY E 1 120 ? 12.765  -50.230 37.721  1.00 78.00  ? 120 GLY E N   1 
ATOM   6341 C  CA  . GLY E 1 120 ? 11.491  -49.627 38.069  1.00 79.46  ? 120 GLY E CA  1 
ATOM   6342 C  C   . GLY E 1 120 ? 11.017  -48.514 37.157  1.00 82.71  ? 120 GLY E C   1 
ATOM   6343 O  O   . GLY E 1 120 ? 10.082  -47.792 37.512  1.00 85.92  ? 120 GLY E O   1 
ATOM   6344 N  N   . ASN E 1 121 ? 11.657  -48.339 35.994  1.00 82.83  ? 121 ASN E N   1 
ATOM   6345 C  CA  . ASN E 1 121 ? 11.250  -47.366 34.985  1.00 81.76  ? 121 ASN E CA  1 
ATOM   6346 C  C   . ASN E 1 121 ? 11.122  -48.012 33.607  1.00 83.74  ? 121 ASN E C   1 
ATOM   6347 O  O   . ASN E 1 121 ? 11.032  -47.292 32.604  1.00 89.77  ? 121 ASN E O   1 
ATOM   6348 C  CB  . ASN E 1 121 ? 12.237  -46.183 34.928  1.00 78.30  ? 121 ASN E CB  1 
ATOM   6349 C  CG  . ASN E 1 121 ? 11.825  -45.019 35.838  1.00 81.61  ? 121 ASN E CG  1 
ATOM   6350 O  OD1 . ASN E 1 121 ? 10.644  -44.691 35.957  1.00 79.33  ? 121 ASN E OD1 1 
ATOM   6351 N  ND2 . ASN E 1 121 ? 12.806  -44.397 36.485  1.00 74.85  ? 121 ASN E ND2 1 
ATOM   6352 N  N   . ASN E 1 122 ? 11.112  -49.347 33.536  1.00 83.29  ? 122 ASN E N   1 
ATOM   6353 C  CA  . ASN E 1 122 ? 10.960  -50.098 32.286  1.00 80.63  ? 122 ASN E CA  1 
ATOM   6354 C  C   . ASN E 1 122 ? 11.932  -49.607 31.217  1.00 85.43  ? 122 ASN E C   1 
ATOM   6355 O  O   . ASN E 1 122 ? 11.556  -49.325 30.075  1.00 87.20  ? 122 ASN E O   1 
ATOM   6356 C  CB  . ASN E 1 122 ? 9.520   -50.039 31.786  1.00 86.15  ? 122 ASN E CB  1 
ATOM   6357 C  CG  . ASN E 1 122 ? 8.524   -50.302 32.885  1.00 94.90  ? 122 ASN E CG  1 
ATOM   6358 O  OD1 . ASN E 1 122 ? 8.851   -50.938 33.895  1.00 92.94  ? 122 ASN E OD1 1 
ATOM   6359 N  ND2 . ASN E 1 122 ? 7.300   -49.813 32.705  1.00 95.79  ? 122 ASN E ND2 1 
ATOM   6360 N  N   . ASP E 1 123 ? 13.201  -49.493 31.609  1.00 82.13  ? 123 ASP E N   1 
ATOM   6361 C  CA  . ASP E 1 123 ? 14.268  -49.121 30.694  1.00 72.48  ? 123 ASP E CA  1 
ATOM   6362 C  C   . ASP E 1 123 ? 15.177  -50.323 30.513  1.00 67.76  ? 123 ASP E C   1 
ATOM   6363 O  O   . ASP E 1 123 ? 16.202  -50.436 31.192  1.00 63.99  ? 123 ASP E O   1 
ATOM   6364 C  CB  . ASP E 1 123 ? 15.052  -47.915 31.211  1.00 72.32  ? 123 ASP E CB  1 
ATOM   6365 C  CG  . ASP E 1 123 ? 15.832  -47.216 30.114  1.00 65.20  ? 123 ASP E CG  1 
ATOM   6366 O  OD1 . ASP E 1 123 ? 15.959  -47.788 29.007  1.00 68.96  ? 123 ASP E OD1 1 
ATOM   6367 O  OD2 . ASP E 1 123 ? 16.302  -46.087 30.361  1.00 69.23  ? 123 ASP E OD2 1 
ATOM   6368 N  N   . PRO E 1 124 ? 14.824  -51.239 29.610  1.00 73.35  ? 124 PRO E N   1 
ATOM   6369 C  CA  . PRO E 1 124 ? 15.639  -52.449 29.422  1.00 66.90  ? 124 PRO E CA  1 
ATOM   6370 C  C   . PRO E 1 124 ? 17.076  -52.165 29.042  1.00 70.53  ? 124 PRO E C   1 
ATOM   6371 O  O   . PRO E 1 124 ? 17.979  -52.909 29.453  1.00 72.77  ? 124 PRO E O   1 
ATOM   6372 C  CB  . PRO E 1 124 ? 14.902  -53.184 28.295  1.00 67.78  ? 124 PRO E CB  1 
ATOM   6373 C  CG  . PRO E 1 124 ? 13.508  -52.629 28.328  1.00 70.60  ? 124 PRO E CG  1 
ATOM   6374 C  CD  . PRO E 1 124 ? 13.667  -51.203 28.705  1.00 74.01  ? 124 PRO E CD  1 
ATOM   6375 N  N   . CYS E 1 125 ? 17.317  -51.102 28.271  1.00 73.47  ? 125 CYS E N   1 
ATOM   6376 C  CA  . CYS E 1 125 ? 18.656  -50.829 27.757  1.00 73.71  ? 125 CYS E CA  1 
ATOM   6377 C  C   . CYS E 1 125 ? 19.549  -50.162 28.793  1.00 68.63  ? 125 CYS E C   1 
ATOM   6378 O  O   . CYS E 1 125 ? 20.768  -50.346 28.763  1.00 68.43  ? 125 CYS E O   1 
ATOM   6379 C  CB  . CYS E 1 125 ? 18.571  -49.943 26.519  1.00 65.19  ? 125 CYS E CB  1 
ATOM   6380 S  SG  . CYS E 1 125 ? 17.533  -50.643 25.228  1.00 85.22  ? 125 CYS E SG  1 
ATOM   6381 N  N   . LEU E 1 126 ? 18.978  -49.371 29.702  1.00 62.51  ? 126 LEU E N   1 
ATOM   6382 C  CA  . LEU E 1 126 ? 19.784  -48.827 30.785  1.00 61.29  ? 126 LEU E CA  1 
ATOM   6383 C  C   . LEU E 1 126 ? 20.268  -49.945 31.704  1.00 69.04  ? 126 LEU E C   1 
ATOM   6384 O  O   . LEU E 1 126 ? 21.476  -50.106 31.910  1.00 62.94  ? 126 LEU E O   1 
ATOM   6385 C  CB  . LEU E 1 126 ? 18.992  -47.774 31.557  1.00 60.51  ? 126 LEU E CB  1 
ATOM   6386 C  CG  . LEU E 1 126 ? 19.791  -47.054 32.639  1.00 67.62  ? 126 LEU E CG  1 
ATOM   6387 C  CD1 . LEU E 1 126 ? 21.185  -46.663 32.129  1.00 55.76  ? 126 LEU E CD1 1 
ATOM   6388 C  CD2 . LEU E 1 126 ? 19.021  -45.842 33.133  1.00 61.88  ? 126 LEU E CD2 1 
ATOM   6389 N  N   . THR E 1 127 ? 19.338  -50.754 32.239  1.00 73.43  ? 127 THR E N   1 
ATOM   6390 C  CA  . THR E 1 127 ? 19.734  -51.888 33.076  1.00 73.61  ? 127 THR E CA  1 
ATOM   6391 C  C   . THR E 1 127 ? 20.686  -52.825 32.340  1.00 68.05  ? 127 THR E C   1 
ATOM   6392 O  O   . THR E 1 127 ? 21.579  -53.401 32.960  1.00 73.89  ? 127 THR E O   1 
ATOM   6393 C  CB  . THR E 1 127 ? 18.519  -52.690 33.562  1.00 71.77  ? 127 THR E CB  1 
ATOM   6394 O  OG1 . THR E 1 127 ? 18.205  -53.693 32.591  1.00 73.63  ? 127 THR E OG1 1 
ATOM   6395 C  CG2 . THR E 1 127 ? 17.311  -51.808 33.774  1.00 60.83  ? 127 THR E CG2 1 
ATOM   6396 N  N   . LYS E 1 128 ? 20.522  -52.991 31.029  1.00 66.36  ? 128 LYS E N   1 
ATOM   6397 C  CA  . LYS E 1 128 ? 21.500  -53.764 30.267  1.00 72.89  ? 128 LYS E CA  1 
ATOM   6398 C  C   . LYS E 1 128 ? 22.896  -53.139 30.362  1.00 77.32  ? 128 LYS E C   1 
ATOM   6399 O  O   . LYS E 1 128 ? 23.880  -53.833 30.647  1.00 75.51  ? 128 LYS E O   1 
ATOM   6400 C  CB  . LYS E 1 128 ? 21.054  -53.888 28.805  1.00 78.45  ? 128 LYS E CB  1 
ATOM   6401 C  CG  . LYS E 1 128 ? 21.815  -54.955 28.014  1.00 83.10  ? 128 LYS E CG  1 
ATOM   6402 C  CD  . LYS E 1 128 ? 22.783  -54.343 27.011  1.00 80.27  ? 128 LYS E CD  1 
ATOM   6403 C  CE  . LYS E 1 128 ? 23.735  -55.394 26.461  1.00 79.67  ? 128 LYS E CE  1 
ATOM   6404 N  NZ  . LYS E 1 128 ? 23.025  -56.668 26.159  1.00 90.91  ? 128 LYS E NZ  1 
ATOM   6405 N  N   . LEU E 1 129 ? 22.985  -51.833 30.197  1.00 72.51  ? 129 LEU E N   1 
ATOM   6406 C  CA  . LEU E 1 129 ? 24.252  -51.169 30.295  1.00 72.59  ? 129 LEU E CA  1 
ATOM   6407 C  C   . LEU E 1 129 ? 24.754  -51.188 31.717  1.00 75.01  ? 129 LEU E C   1 
ATOM   6408 O  O   . LEU E 1 129 ? 25.898  -51.481 31.963  1.00 77.87  ? 129 LEU E O   1 
ATOM   6409 C  CB  . LEU E 1 129 ? 24.149  -49.747 29.809  1.00 66.55  ? 129 LEU E CB  1 
ATOM   6410 C  CG  . LEU E 1 129 ? 25.460  -49.001 29.925  1.00 69.68  ? 129 LEU E CG  1 
ATOM   6411 C  CD1 . LEU E 1 129 ? 26.420  -49.353 28.813  1.00 59.82  ? 129 LEU E CD1 1 
ATOM   6412 C  CD2 . LEU E 1 129 ? 25.242  -47.519 30.024  1.00 58.04  ? 129 LEU E CD2 1 
ATOM   6413 N  N   . LEU E 1 130 ? 23.887  -50.900 32.665  1.00 67.56  ? 130 LEU E N   1 
ATOM   6414 C  CA  . LEU E 1 130 ? 24.257  -50.909 34.053  1.00 63.37  ? 130 LEU E CA  1 
ATOM   6415 C  C   . LEU E 1 130 ? 24.653  -52.256 34.482  1.00 76.39  ? 130 LEU E C   1 
ATOM   6416 O  O   . LEU E 1 130 ? 25.620  -52.416 35.160  1.00 81.82  ? 130 LEU E O   1 
ATOM   6417 C  CB  . LEU E 1 130 ? 23.111  -50.497 34.922  1.00 62.40  ? 130 LEU E CB  1 
ATOM   6418 C  CG  . LEU E 1 130 ? 22.785  -49.053 34.724  1.00 71.25  ? 130 LEU E CG  1 
ATOM   6419 C  CD1 . LEU E 1 130 ? 21.953  -48.555 35.863  1.00 68.35  ? 130 LEU E CD1 1 
ATOM   6420 C  CD2 . LEU E 1 130 ? 24.093  -48.314 34.663  1.00 68.11  ? 130 LEU E CD2 1 
ATOM   6421 N  N   . GLU E 1 131 ? 23.923  -53.265 34.055  1.00 82.75  ? 131 GLU E N   1 
ATOM   6422 C  CA  . GLU E 1 131 ? 24.237  -54.621 34.426  1.00 80.76  ? 131 GLU E CA  1 
ATOM   6423 C  C   . GLU E 1 131 ? 25.582  -55.015 33.935  1.00 82.01  ? 131 GLU E C   1 
ATOM   6424 O  O   . GLU E 1 131 ? 26.244  -55.741 34.616  1.00 87.84  ? 131 GLU E O   1 
ATOM   6425 C  CB  . GLU E 1 131 ? 23.210  -55.603 33.894  1.00 81.47  ? 131 GLU E CB  1 
ATOM   6426 C  CG  . GLU E 1 131 ? 22.176  -56.018 34.899  1.00 75.18  ? 131 GLU E CG  1 
ATOM   6427 C  CD  . GLU E 1 131 ? 20.924  -56.507 34.255  1.00 81.75  ? 131 GLU E CD  1 
ATOM   6428 O  OE1 . GLU E 1 131 ? 19.905  -56.548 34.947  1.00 83.21  ? 131 GLU E OE1 1 
ATOM   6429 O  OE2 . GLU E 1 131 ? 20.954  -56.834 33.064  1.00 80.52  ? 131 GLU E OE2 1 
ATOM   6430 N  N   . ASP E 1 132 ? 25.964  -54.634 32.733  1.00 77.25  ? 132 ASP E N   1 
ATOM   6431 C  CA  . ASP E 1 132 ? 27.275  -54.996 32.316  1.00 86.39  ? 132 ASP E CA  1 
ATOM   6432 C  C   . ASP E 1 132 ? 28.344  -54.347 33.167  1.00 85.51  ? 132 ASP E C   1 
ATOM   6433 O  O   . ASP E 1 132 ? 29.124  -55.045 33.717  1.00 87.49  ? 132 ASP E O   1 
ATOM   6434 C  CB  . ASP E 1 132 ? 27.515  -54.623 30.863  1.00 86.99  ? 132 ASP E CB  1 
ATOM   6435 C  CG  . ASP E 1 132 ? 26.604  -55.329 29.941  1.00 87.41  ? 132 ASP E CG  1 
ATOM   6436 O  OD1 . ASP E 1 132 ? 25.827  -56.155 30.427  1.00 82.29  ? 132 ASP E OD1 1 
ATOM   6437 O  OD2 . ASP E 1 132 ? 26.593  -55.000 28.748  1.00 88.22  ? 132 ASP E OD2 1 
ATOM   6438 N  N   . GLU E 1 133 ? 28.305  -53.050 33.417  1.00 81.35  ? 133 GLU E N   1 
ATOM   6439 C  CA  . GLU E 1 133 ? 29.405  -52.462 34.163  1.00 82.46  ? 133 GLU E CA  1 
ATOM   6440 C  C   . GLU E 1 133 ? 29.544  -52.976 35.584  1.00 81.20  ? 133 GLU E C   1 
ATOM   6441 O  O   . GLU E 1 133 ? 30.613  -53.315 35.978  1.00 82.60  ? 133 GLU E O   1 
ATOM   6442 C  CB  . GLU E 1 133 ? 29.398  -50.925 34.113  1.00 76.97  ? 133 GLU E CB  1 
ATOM   6443 C  CG  . GLU E 1 133 ? 29.230  -50.319 32.727  1.00 80.42  ? 133 GLU E CG  1 
ATOM   6444 C  CD  . GLU E 1 133 ? 30.513  -49.890 32.034  1.00 88.39  ? 133 GLU E CD  1 
ATOM   6445 O  OE1 . GLU E 1 133 ? 30.828  -50.449 30.978  1.00 86.54  ? 133 GLU E OE1 1 
ATOM   6446 O  OE2 . GLU E 1 133 ? 31.193  -48.964 32.504  1.00 85.26  ? 133 GLU E OE2 1 
ATOM   6447 N  N   . TYR E 1 134 ? 28.443  -53.087 36.302  1.00 81.03  ? 134 TYR E N   1 
ATOM   6448 C  CA  . TYR E 1 134 ? 28.407  -53.581 37.670  1.00 85.05  ? 134 TYR E CA  1 
ATOM   6449 C  C   . TYR E 1 134 ? 28.768  -55.021 37.832  1.00 87.77  ? 134 TYR E C   1 
ATOM   6450 O  O   . TYR E 1 134 ? 29.298  -55.425 38.830  1.00 82.10  ? 134 TYR E O   1 
ATOM   6451 C  CB  . TYR E 1 134 ? 27.033  -53.430 38.271  1.00 80.03  ? 134 TYR E CB  1 
ATOM   6452 C  CG  . TYR E 1 134 ? 26.966  -53.945 39.668  1.00 81.50  ? 134 TYR E CG  1 
ATOM   6453 C  CD1 . TYR E 1 134 ? 27.412  -53.194 40.722  1.00 82.11  ? 134 TYR E CD1 1 
ATOM   6454 C  CD2 . TYR E 1 134 ? 26.466  -55.175 39.935  1.00 83.50  ? 134 TYR E CD2 1 
ATOM   6455 C  CE1 . TYR E 1 134 ? 27.346  -53.651 42.009  1.00 81.43  ? 134 TYR E CE1 1 
ATOM   6456 C  CE2 . TYR E 1 134 ? 26.396  -55.645 41.219  1.00 90.08  ? 134 TYR E CE2 1 
ATOM   6457 C  CZ  . TYR E 1 134 ? 26.834  -54.875 42.250  1.00 88.44  ? 134 TYR E CZ  1 
ATOM   6458 O  OH  . TYR E 1 134 ? 26.753  -55.358 43.516  1.00 86.66  ? 134 TYR E OH  1 
ATOM   6459 N  N   . CYS E 1 135 ? 28.339  -55.825 36.892  1.00 90.73  ? 135 CYS E N   1 
ATOM   6460 C  CA  . CYS E 1 135 ? 28.634  -57.212 36.972  1.00 85.42  ? 135 CYS E CA  1 
ATOM   6461 C  C   . CYS E 1 135 ? 29.834  -57.666 36.148  1.00 91.44  ? 135 CYS E C   1 
ATOM   6462 O  O   . CYS E 1 135 ? 30.762  -58.189 36.716  1.00 87.79  ? 135 CYS E O   1 
ATOM   6463 C  CB  . CYS E 1 135 ? 27.388  -58.012 36.584  1.00 79.98  ? 135 CYS E CB  1 
ATOM   6464 S  SG  . CYS E 1 135 ? 26.120  -58.220 37.852  1.00 87.77  ? 135 CYS E SG  1 
ATOM   6465 N  N   . GLU E 1 136 ? 29.916  -57.307 34.871  1.00 95.85  ? 136 GLU E N   1 
ATOM   6466 C  CA  . GLU E 1 136 ? 30.929  -57.931 34.002  1.00 102.68 ? 136 GLU E CA  1 
ATOM   6467 C  C   . GLU E 1 136 ? 32.319  -57.760 34.396  1.00 100.76 ? 136 GLU E C   1 
ATOM   6468 O  O   . GLU E 1 136 ? 33.113  -58.691 34.317  1.00 103.18 ? 136 GLU E O   1 
ATOM   6469 C  CB  . GLU E 1 136 ? 30.873  -57.433 32.551  1.00 102.91 ? 136 GLU E CB  1 
ATOM   6470 C  CG  . GLU E 1 136 ? 29.983  -58.202 31.614  1.00 99.77  ? 136 GLU E CG  1 
ATOM   6471 C  CD  . GLU E 1 136 ? 30.794  -58.972 30.616  1.00 105.24 ? 136 GLU E CD  1 
ATOM   6472 O  OE1 . GLU E 1 136 ? 30.665  -58.650 29.429  1.00 104.61 ? 136 GLU E OE1 1 
ATOM   6473 O  OE2 . GLU E 1 136 ? 31.572  -59.868 31.016  1.00 106.97 ? 136 GLU E OE2 1 
ATOM   6474 N  N   . GLU E 1 137 ? 32.645  -56.560 34.770  1.00 98.15  ? 137 GLU E N   1 
ATOM   6475 C  CA  . GLU E 1 137 ? 33.999  -56.370 35.155  1.00 101.94 ? 137 GLU E CA  1 
ATOM   6476 C  C   . GLU E 1 137 ? 34.124  -55.782 36.528  1.00 98.08  ? 137 GLU E C   1 
ATOM   6477 O  O   . GLU E 1 137 ? 35.171  -55.267 36.873  1.00 99.50  ? 137 GLU E O   1 
ATOM   6478 C  CB  . GLU E 1 137 ? 34.849  -55.739 34.028  1.00 104.14 ? 137 GLU E CB  1 
ATOM   6479 C  CG  . GLU E 1 137 ? 35.523  -56.793 33.133  1.00 100.55 ? 137 GLU E CG  1 
ATOM   6480 C  CD  . GLU E 1 137 ? 36.064  -56.261 31.818  1.00 103.29 ? 137 GLU E CD  1 
ATOM   6481 O  OE1 . GLU E 1 137 ? 37.283  -56.304 31.607  1.00 94.10  ? 137 GLU E OE1 1 
ATOM   6482 O  OE2 . GLU E 1 137 ? 35.265  -55.819 30.973  1.00 105.99 ? 137 GLU E OE2 1 
ATOM   6483 N  N   . GLN E 1 138 ? 33.047  -55.778 37.300  1.00 86.85  ? 138 GLN E N   1 
ATOM   6484 C  CA  . GLN E 1 138 ? 33.249  -55.334 38.664  1.00 86.95  ? 138 GLN E CA  1 
ATOM   6485 C  C   . GLN E 1 138 ? 33.555  -56.515 39.585  1.00 85.16  ? 138 GLN E C   1 
ATOM   6486 O  O   . GLN E 1 138 ? 33.950  -56.327 40.686  1.00 82.87  ? 138 GLN E O   1 
ATOM   6487 C  CB  . GLN E 1 138 ? 32.269  -54.294 39.166  1.00 82.70  ? 138 GLN E CB  1 
ATOM   6488 C  CG  . GLN E 1 138 ? 32.470  -52.911 38.573  1.00 82.53  ? 138 GLN E CG  1 
ATOM   6489 C  CD  . GLN E 1 138 ? 33.841  -52.314 38.827  1.00 88.20  ? 138 GLN E CD  1 
ATOM   6490 O  OE1 . GLN E 1 138 ? 34.242  -52.109 39.964  1.00 78.17  ? 138 GLN E OE1 1 
ATOM   6491 N  NE2 . GLN E 1 138 ? 34.548  -51.993 37.757  1.00 84.31  ? 138 GLN E NE2 1 
ATOM   6492 N  N   . CYS E 1 139 ? 33.443  -57.728 39.024  1.00 93.17  ? 139 CYS E N   1 
ATOM   6493 C  CA  . CYS E 1 139 ? 33.842  -59.056 39.548  1.00 85.30  ? 139 CYS E CA  1 
ATOM   6494 C  C   . CYS E 1 139 ? 35.226  -59.384 38.931  1.00 82.13  ? 139 CYS E C   1 
ATOM   6495 O  O   . CYS E 1 139 ? 35.632  -60.516 38.891  1.00 83.71  ? 139 CYS E O   1 
ATOM   6496 C  CB  . CYS E 1 139 ? 32.837  -60.170 39.165  1.00 93.76  ? 139 CYS E CB  1 
ATOM   6497 S  SG  . CYS E 1 139 ? 33.110  -61.889 39.712  1.00 90.26  ? 139 CYS E SG  1 
ATOM   6498 N  N   . ASP E 1 140 ? 35.861  -58.386 38.334  1.00 83.85  ? 140 ASP E N   1 
ATOM   6499 C  CA  . ASP E 1 140 ? 37.166  -58.372 37.775  1.00 80.00  ? 140 ASP E CA  1 
ATOM   6500 C  C   . ASP E 1 140 ? 37.781  -57.464 38.810  1.00 75.96  ? 140 ASP E C   1 
ATOM   6501 O  O   . ASP E 1 140 ? 38.596  -57.903 39.558  1.00 70.50  ? 140 ASP E O   1 
ATOM   6502 C  CB  . ASP E 1 140 ? 37.107  -57.770 36.357  1.00 93.69  ? 140 ASP E CB  1 
ATOM   6503 C  CG  . ASP E 1 140 ? 38.327  -56.933 35.967  1.00 93.37  ? 140 ASP E CG  1 
ATOM   6504 O  OD1 . ASP E 1 140 ? 38.211  -55.706 35.979  1.00 87.19  ? 140 ASP E OD1 1 
ATOM   6505 O  OD2 . ASP E 1 140 ? 39.376  -57.474 35.652  1.00 100.90 ? 140 ASP E OD2 1 
ATOM   6506 N  N   . SER E 1 141 ? 37.295  -56.238 38.936  1.00 77.97  ? 141 SER E N   1 
ATOM   6507 C  CA  A SER E 1 141 ? 38.107  -55.263 39.657  0.90 71.43  ? 141 SER E CA  1 
ATOM   6508 C  CA  B SER E 1 141 ? 38.107  -55.263 39.658  0.10 71.64  ? 141 SER E CA  1 
ATOM   6509 C  C   . SER E 1 141 ? 37.979  -55.402 41.174  1.00 65.95  ? 141 SER E C   1 
ATOM   6510 O  O   . SER E 1 141 ? 38.961  -55.207 41.897  1.00 60.45  ? 141 SER E O   1 
ATOM   6511 C  CB  A SER E 1 141 ? 37.723  -53.848 39.222  0.90 75.75  ? 141 SER E CB  1 
ATOM   6512 C  CB  B SER E 1 141 ? 37.727  -53.848 39.224  0.10 75.48  ? 141 SER E CB  1 
ATOM   6513 O  OG  A SER E 1 141 ? 38.601  -52.882 39.780  0.90 74.21  ? 141 SER E OG  1 
ATOM   6514 O  OG  B SER E 1 141 ? 38.455  -52.877 39.955  0.10 73.82  ? 141 SER E OG  1 
ATOM   6515 N  N   . ILE E 1 142 ? 36.784  -55.715 41.688  1.00 68.97  ? 142 ILE E N   1 
ATOM   6516 C  CA  . ILE E 1 142 ? 36.667  -55.876 43.140  1.00 63.27  ? 142 ILE E CA  1 
ATOM   6517 C  C   . ILE E 1 142 ? 37.327  -57.178 43.594  1.00 65.20  ? 142 ILE E C   1 
ATOM   6518 O  O   . ILE E 1 142 ? 37.854  -57.259 44.711  1.00 56.86  ? 142 ILE E O   1 
ATOM   6519 C  CB  . ILE E 1 142 ? 35.195  -55.789 43.590  1.00 64.13  ? 142 ILE E CB  1 
ATOM   6520 C  CG1 . ILE E 1 142 ? 34.742  -54.325 43.603  1.00 67.01  ? 142 ILE E CG1 1 
ATOM   6521 C  CG2 . ILE E 1 142 ? 34.996  -56.413 44.980  1.00 61.38  ? 142 ILE E CG2 1 
ATOM   6522 C  CD1 . ILE E 1 142 ? 33.245  -54.142 43.591  1.00 66.52  ? 142 ILE E CD1 1 
ATOM   6523 N  N   . LYS E 1 143 ? 37.349  -58.201 42.731  1.00 71.19  ? 143 LYS E N   1 
ATOM   6524 C  CA  . LYS E 1 143 ? 38.049  -59.435 43.075  1.00 62.58  ? 143 LYS E CA  1 
ATOM   6525 C  C   . LYS E 1 143 ? 39.558  -59.235 43.054  1.00 57.11  ? 143 LYS E C   1 
ATOM   6526 O  O   . LYS E 1 143 ? 40.268  -59.775 43.911  1.00 50.51  ? 143 LYS E O   1 
ATOM   6527 C  CB  . LYS E 1 143 ? 37.659  -60.566 42.119  1.00 68.73  ? 143 LYS E CB  1 
ATOM   6528 C  CG  . LYS E 1 143 ? 38.177  -61.946 42.558  1.00 73.58  ? 143 LYS E CG  1 
ATOM   6529 C  CD  . LYS E 1 143 ? 38.525  -62.864 41.389  1.00 76.90  ? 143 LYS E CD  1 
ATOM   6530 C  CE  . LYS E 1 143 ? 39.251  -64.119 41.883  1.00 77.44  ? 143 LYS E CE  1 
ATOM   6531 N  NZ  . LYS E 1 143 ? 40.514  -64.396 41.128  1.00 89.00  ? 143 LYS E NZ  1 
ATOM   6532 N  N   . LYS E 1 144 ? 40.069  -58.476 42.073  1.00 54.96  ? 144 LYS E N   1 
ATOM   6533 C  CA  . LYS E 1 144 ? 41.514  -58.362 41.925  1.00 50.00  ? 144 LYS E CA  1 
ATOM   6534 C  C   . LYS E 1 144 ? 42.116  -57.544 43.051  1.00 49.66  ? 144 LYS E C   1 
ATOM   6535 O  O   . LYS E 1 144 ? 43.206  -57.873 43.544  1.00 45.97  ? 144 LYS E O   1 
ATOM   6536 C  CB  . LYS E 1 144 ? 41.889  -57.775 40.564  1.00 50.76  ? 144 LYS E CB  1 
ATOM   6537 C  CG  . LYS E 1 144 ? 41.607  -58.707 39.368  1.00 71.51  ? 144 LYS E CG  1 
ATOM   6538 C  CD  . LYS E 1 144 ? 42.255  -60.110 39.503  1.00 74.66  ? 144 LYS E CD  1 
ATOM   6539 C  CE  . LYS E 1 144 ? 41.205  -61.191 39.857  1.00 74.77  ? 144 LYS E CE  1 
ATOM   6540 N  NZ  . LYS E 1 144 ? 41.716  -62.301 40.742  1.00 72.60  ? 144 LYS E NZ  1 
ATOM   6541 N  N   . ILE E 1 145 ? 41.419  -56.492 43.489  1.00 43.63  ? 145 ILE E N   1 
ATOM   6542 C  CA  . ILE E 1 145 ? 41.886  -55.745 44.653  1.00 46.74  ? 145 ILE E CA  1 
ATOM   6543 C  C   . ILE E 1 145 ? 41.802  -56.608 45.911  1.00 45.06  ? 145 ILE E C   1 
ATOM   6544 O  O   . ILE E 1 145 ? 42.679  -56.540 46.782  1.00 42.72  ? 145 ILE E O   1 
ATOM   6545 C  CB  . ILE E 1 145 ? 41.101  -54.430 44.812  1.00 43.20  ? 145 ILE E CB  1 
ATOM   6546 C  CG1 . ILE E 1 145 ? 41.374  -53.498 43.640  1.00 41.94  ? 145 ILE E CG1 1 
ATOM   6547 C  CG2 . ILE E 1 145 ? 41.485  -53.732 46.112  1.00 44.77  ? 145 ILE E CG2 1 
ATOM   6548 C  CD1 . ILE E 1 145 ? 40.400  -52.335 43.558  1.00 45.00  ? 145 ILE E CD1 1 
ATOM   6549 N  N   . GLY E 1 146 ? 40.747  -57.429 46.028  1.00 42.68  ? 146 GLY E N   1 
ATOM   6550 C  CA  . GLY E 1 146 ? 40.652  -58.340 47.154  1.00 41.34  ? 146 GLY E CA  1 
ATOM   6551 C  C   . GLY E 1 146 ? 41.818  -59.309 47.206  1.00 41.92  ? 146 GLY E C   1 
ATOM   6552 O  O   . GLY E 1 146 ? 42.395  -59.553 48.270  1.00 39.23  ? 146 GLY E O   1 
ATOM   6553 N  N   . CYS E 1 147 ? 42.195  -59.861 46.054  1.00 40.12  ? 147 CYS E N   1 
ATOM   6554 C  CA  . CYS E 1 147 ? 43.338  -60.767 46.020  1.00 43.21  ? 147 CYS E CA  1 
ATOM   6555 C  C   . CYS E 1 147 ? 44.645  -60.046 46.323  1.00 40.55  ? 147 CYS E C   1 
ATOM   6556 O  O   . CYS E 1 147 ? 45.525  -60.610 46.988  1.00 37.37  ? 147 CYS E O   1 
ATOM   6557 C  CB  . CYS E 1 147 ? 43.418  -61.477 44.669  1.00 44.81  ? 147 CYS E CB  1 
ATOM   6558 S  SG  . CYS E 1 147 ? 42.709  -63.105 44.765  1.00 64.08  ? 147 CYS E SG  1 
ATOM   6559 N  N   . MET E 1 148 ? 44.793  -58.802 45.854  1.00 34.50  ? 148 MET E N   1 
ATOM   6560 C  CA  . MET E 1 148 ? 46.003  -58.060 46.174  1.00 39.90  ? 148 MET E CA  1 
ATOM   6561 C  C   . MET E 1 148 ? 46.110  -57.845 47.671  1.00 44.05  ? 148 MET E C   1 
ATOM   6562 O  O   . MET E 1 148 ? 47.204  -57.940 48.245  1.00 41.92  ? 148 MET E O   1 
ATOM   6563 C  CB  . MET E 1 148 ? 46.031  -56.729 45.429  1.00 38.34  ? 148 MET E CB  1 
ATOM   6564 C  CG  . MET E 1 148 ? 46.120  -56.895 43.932  1.00 38.76  ? 148 MET E CG  1 
ATOM   6565 S  SD  . MET E 1 148 ? 45.686  -55.392 43.039  1.00 44.21  ? 148 MET E SD  1 
ATOM   6566 C  CE  . MET E 1 148 ? 47.150  -54.428 43.344  1.00 41.40  ? 148 MET E CE  1 
ATOM   6567 N  N   . ILE E 1 149 ? 44.975  -57.586 48.325  1.00 38.94  ? 149 ILE E N   1 
ATOM   6568 C  CA  . ILE E 1 149 ? 44.980  -57.391 49.768  1.00 37.70  ? 149 ILE E CA  1 
ATOM   6569 C  C   . ILE E 1 149 ? 45.377  -58.673 50.480  1.00 40.92  ? 149 ILE E C   1 
ATOM   6570 O  O   . ILE E 1 149 ? 46.186  -58.649 51.416  1.00 42.56  ? 149 ILE E O   1 
ATOM   6571 C  CB  . ILE E 1 149 ? 43.609  -56.880 50.237  1.00 43.07  ? 149 ILE E CB  1 
ATOM   6572 C  CG1 . ILE E 1 149 ? 43.400  -55.446 49.739  1.00 39.91  ? 149 ILE E CG1 1 
ATOM   6573 C  CG2 . ILE E 1 149 ? 43.508  -57.009 51.735  1.00 35.94  ? 149 ILE E CG2 1 
ATOM   6574 C  CD1 . ILE E 1 149 ? 42.023  -54.904 49.985  1.00 44.95  ? 149 ILE E CD1 1 
ATOM   6575 N  N   . THR E 1 150 ? 44.805  -59.813 50.056  1.00 44.78  ? 150 THR E N   1 
ATOM   6576 C  CA  . THR E 1 150 ? 45.187  -61.115 50.614  1.00 36.21  ? 150 THR E CA  1 
ATOM   6577 C  C   . THR E 1 150 ? 46.659  -61.420 50.351  1.00 41.88  ? 150 THR E C   1 
ATOM   6578 O  O   . THR E 1 150 ? 47.376  -61.893 51.240  1.00 45.13  ? 150 THR E O   1 
ATOM   6579 C  CB  . THR E 1 150 ? 44.312  -62.210 50.009  1.00 40.49  ? 150 THR E CB  1 
ATOM   6580 O  OG1 . THR E 1 150 ? 42.964  -62.086 50.488  1.00 48.47  ? 150 THR E OG1 1 
ATOM   6581 C  CG2 . THR E 1 150 ? 44.853  -63.601 50.353  1.00 34.02  ? 150 THR E CG2 1 
ATOM   6582 N  N   . LYS E 1 151 ? 47.132  -61.148 49.136  1.00 42.13  ? 151 LYS E N   1 
ATOM   6583 C  CA  . LYS E 1 151 ? 48.514  -61.462 48.803  1.00 40.49  ? 151 LYS E CA  1 
ATOM   6584 C  C   . LYS E 1 151 ? 49.489  -60.600 49.606  1.00 42.72  ? 151 LYS E C   1 
ATOM   6585 O  O   . LYS E 1 151 ? 50.514  -61.102 50.086  1.00 44.13  ? 151 LYS E O   1 
ATOM   6586 C  CB  . LYS E 1 151 ? 48.730  -61.303 47.295  1.00 34.66  ? 151 LYS E CB  1 
ATOM   6587 C  CG  . LYS E 1 151 ? 50.204  -61.307 46.904  1.00 50.00  ? 151 LYS E CG  1 
ATOM   6588 C  CD  . LYS E 1 151 ? 50.422  -61.487 45.404  1.00 44.61  ? 151 LYS E CD  1 
ATOM   6589 C  CE  . LYS E 1 151 ? 51.904  -61.479 45.076  1.00 45.40  ? 151 LYS E CE  1 
ATOM   6590 N  NZ  . LYS E 1 151 ? 52.163  -61.152 43.640  1.00 54.50  ? 151 LYS E NZ  1 
ATOM   6591 N  N   . LEU E 1 152 ? 49.177  -59.312 49.789  1.00 36.61  ? 152 LEU E N   1 
ATOM   6592 C  CA  . LEU E 1 152 ? 50.068  -58.431 50.544  1.00 40.49  ? 152 LEU E CA  1 
ATOM   6593 C  C   . LEU E 1 152 ? 50.046  -58.744 52.034  1.00 43.69  ? 152 LEU E C   1 
ATOM   6594 O  O   . LEU E 1 152 ? 51.056  -58.559 52.727  1.00 36.60  ? 152 LEU E O   1 
ATOM   6595 C  CB  . LEU E 1 152 ? 49.688  -56.972 50.310  1.00 39.38  ? 152 LEU E CB  1 
ATOM   6596 C  CG  . LEU E 1 152 ? 50.477  -55.833 50.956  1.00 43.95  ? 152 LEU E CG  1 
ATOM   6597 C  CD1 . LEU E 1 152 ? 51.977  -56.003 50.795  1.00 41.90  ? 152 LEU E CD1 1 
ATOM   6598 C  CD2 . LEU E 1 152 ? 50.028  -54.498 50.341  1.00 44.76  ? 152 LEU E CD2 1 
ATOM   6599 N  N   . LYS E 1 153 ? 48.914  -59.214 52.556  1.00 41.08  ? 153 LYS E N   1 
ATOM   6600 C  CA  . LYS E 1 153 ? 48.939  -59.680 53.938  1.00 46.40  ? 153 LYS E CA  1 
ATOM   6601 C  C   . LYS E 1 153 ? 49.826  -60.915 54.081  1.00 44.29  ? 153 LYS E C   1 
ATOM   6602 O  O   . LYS E 1 153 ? 50.579  -61.023 55.053  1.00 43.60  ? 153 LYS E O   1 
ATOM   6603 C  CB  . LYS E 1 153 ? 47.524  -59.956 54.441  1.00 36.07  ? 153 LYS E CB  1 
ATOM   6604 C  CG  . LYS E 1 153 ? 46.705  -58.706 54.670  1.00 36.52  ? 153 LYS E CG  1 
ATOM   6605 C  CD  . LYS E 1 153 ? 45.307  -59.091 55.134  1.00 39.09  ? 153 LYS E CD  1 
ATOM   6606 C  CE  . LYS E 1 153 ? 44.482  -57.872 55.482  1.00 45.67  ? 153 LYS E CE  1 
ATOM   6607 N  NZ  . LYS E 1 153 ? 43.027  -58.192 55.416  1.00 59.96  ? 153 LYS E NZ  1 
ATOM   6608 N  N   . ARG E 1 154 ? 49.789  -61.829 53.099  1.00 40.04  ? 154 ARG E N   1 
ATOM   6609 C  CA  . ARG E 1 154 ? 50.569  -63.064 53.199  1.00 45.45  ? 154 ARG E CA  1 
ATOM   6610 C  C   . ARG E 1 154 ? 52.053  -62.795 53.043  1.00 44.63  ? 154 ARG E C   1 
ATOM   6611 O  O   . ARG E 1 154 ? 52.844  -63.175 53.909  1.00 41.20  ? 154 ARG E O   1 
ATOM   6612 C  CB  . ARG E 1 154 ? 50.132  -64.096 52.151  1.00 41.59  ? 154 ARG E CB  1 
ATOM   6613 C  CG  . ARG E 1 154 ? 51.220  -65.131 51.892  1.00 46.21  ? 154 ARG E CG  1 
ATOM   6614 C  CD  . ARG E 1 154 ? 50.809  -66.163 50.857  1.00 49.48  ? 154 ARG E CD  1 
ATOM   6615 N  NE  . ARG E 1 154 ? 49.510  -66.721 51.201  1.00 51.21  ? 154 ARG E NE  1 
ATOM   6616 C  CZ  . ARG E 1 154 ? 48.408  -66.488 50.505  1.00 52.77  ? 154 ARG E CZ  1 
ATOM   6617 N  NH1 . ARG E 1 154 ? 48.463  -65.704 49.410  1.00 49.32  ? 154 ARG E NH1 1 
ATOM   6618 N  NH2 . ARG E 1 154 ? 47.263  -67.028 50.909  1.00 41.66  ? 154 ARG E NH2 1 
ATOM   6619 N  N   . CYS E 1 155 ? 52.455  -62.165 51.925  1.00 46.43  ? 155 CYS E N   1 
ATOM   6620 C  CA  . CYS E 1 155 ? 53.854  -61.789 51.706  1.00 49.67  ? 155 CYS E CA  1 
ATOM   6621 C  C   . CYS E 1 155 ? 54.391  -60.885 52.802  1.00 47.88  ? 155 CYS E C   1 
ATOM   6622 O  O   . CYS E 1 155 ? 55.607  -60.687 52.882  1.00 52.56  ? 155 CYS E O   1 
ATOM   6623 C  CB  . CYS E 1 155 ? 54.051  -61.089 50.342  1.00 45.59  ? 155 CYS E CB  1 
ATOM   6624 S  SG  . CYS E 1 155 ? 53.636  -62.048 48.840  1.00 73.10  ? 155 CYS E SG  1 
ATOM   6625 N  N   . GLY E 1 156 ? 53.526  -60.367 53.663  1.00 49.65  ? 156 GLY E N   1 
ATOM   6626 C  CA  . GLY E 1 156 ? 53.929  -59.506 54.738  1.00 49.96  ? 156 GLY E CA  1 
ATOM   6627 C  C   . GLY E 1 156 ? 53.649  -58.111 54.259  1.00 57.96  ? 156 GLY E C   1 
ATOM   6628 O  O   . GLY E 1 156 ? 54.136  -57.689 53.201  1.00 58.98  ? 156 GLY E O   1 
ATOM   6629 N  N   . PRO E 1 157 ? 52.806  -57.383 54.993  1.00 56.05  ? 157 PRO E N   1 
ATOM   6630 C  CA  . PRO E 1 157 ? 52.280  -56.113 54.477  1.00 53.17  ? 157 PRO E CA  1 
ATOM   6631 C  C   . PRO E 1 157 ? 53.274  -54.969 54.528  1.00 53.92  ? 157 PRO E C   1 
ATOM   6632 O  O   . PRO E 1 157 ? 52.947  -53.875 54.052  1.00 60.72  ? 157 PRO E O   1 
ATOM   6633 C  CB  . PRO E 1 157 ? 51.080  -55.830 55.389  1.00 55.62  ? 157 PRO E CB  1 
ATOM   6634 C  CG  . PRO E 1 157 ? 51.217  -56.786 56.579  1.00 51.12  ? 157 PRO E CG  1 
ATOM   6635 C  CD  . PRO E 1 157 ? 52.460  -57.607 56.403  1.00 53.72  ? 157 PRO E CD  1 
ATOM   6636 N  N   . THR E 1 158 ? 54.461  -55.190 55.095  1.00 55.98  ? 158 THR E N   1 
ATOM   6637 C  CA  . THR E 1 158 ? 55.492  -54.168 55.208  1.00 52.89  ? 158 THR E CA  1 
ATOM   6638 C  C   . THR E 1 158 ? 56.862  -54.788 54.937  1.00 55.17  ? 158 THR E C   1 
ATOM   6639 O  O   . THR E 1 158 ? 57.027  -56.015 54.892  1.00 53.88  ? 158 THR E O   1 
ATOM   6640 C  CB  . THR E 1 158 ? 55.491  -53.528 56.602  1.00 47.04  ? 158 THR E CB  1 
ATOM   6641 O  OG1 . THR E 1 158 ? 55.677  -54.559 57.576  1.00 56.72  ? 158 THR E OG1 1 
ATOM   6642 C  CG2 . THR E 1 158 ? 54.172  -52.814 56.885  1.00 44.68  ? 158 THR E CG2 1 
ATOM   6643 N  N   . GLY E 1 159 ? 57.858  -53.919 54.773  1.00 53.32  ? 159 GLY E N   1 
ATOM   6644 C  CA  . GLY E 1 159 ? 59.230  -54.393 54.690  1.00 46.58  ? 159 GLY E CA  1 
ATOM   6645 C  C   . GLY E 1 159 ? 59.534  -55.094 53.378  1.00 46.48  ? 159 GLY E C   1 
ATOM   6646 O  O   . GLY E 1 159 ? 59.112  -54.676 52.290  1.00 45.94  ? 159 GLY E O   1 
ATOM   6647 N  N   . LEU E 1 160 ? 60.295  -56.180 53.482  1.00 47.53  ? 160 LEU E N   1 
ATOM   6648 C  CA  . LEU E 1 160 ? 60.706  -56.887 52.277  1.00 47.92  ? 160 LEU E CA  1 
ATOM   6649 C  C   . LEU E 1 160 ? 59.495  -57.392 51.504  1.00 44.99  ? 160 LEU E C   1 
ATOM   6650 O  O   . LEU E 1 160 ? 59.476  -57.347 50.270  1.00 46.31  ? 160 LEU E O   1 
ATOM   6651 C  CB  . LEU E 1 160 ? 61.653  -58.032 52.642  1.00 40.72  ? 160 LEU E CB  1 
ATOM   6652 C  CG  . LEU E 1 160 ? 62.192  -58.808 51.441  1.00 53.17  ? 160 LEU E CG  1 
ATOM   6653 C  CD1 . LEU E 1 160 ? 63.056  -57.935 50.536  1.00 58.42  ? 160 LEU E CD1 1 
ATOM   6654 C  CD2 . LEU E 1 160 ? 62.999  -59.980 51.923  1.00 56.56  ? 160 LEU E CD2 1 
ATOM   6655 N  N   . GLY E 1 161 ? 58.455  -57.834 52.216  1.00 52.32  ? 161 GLY E N   1 
ATOM   6656 C  CA  . GLY E 1 161 ? 57.284  -58.371 51.540  1.00 48.83  ? 161 GLY E CA  1 
ATOM   6657 C  C   . GLY E 1 161 ? 56.518  -57.321 50.757  1.00 48.87  ? 161 GLY E C   1 
ATOM   6658 O  O   . GLY E 1 161 ? 55.973  -57.609 49.685  1.00 46.50  ? 161 GLY E O   1 
ATOM   6659 N  N   . GLU E 1 162 ? 56.446  -56.093 51.284  1.00 46.81  ? 162 GLU E N   1 
ATOM   6660 C  CA  . GLU E 1 162 ? 55.853  -55.015 50.504  1.00 44.86  ? 162 GLU E CA  1 
ATOM   6661 C  C   . GLU E 1 162 ? 56.656  -54.761 49.231  1.00 44.49  ? 162 GLU E C   1 
ATOM   6662 O  O   . GLU E 1 162 ? 56.081  -54.573 48.152  1.00 44.87  ? 162 GLU E O   1 
ATOM   6663 C  CB  . GLU E 1 162 ? 55.737  -53.747 51.350  1.00 45.73  ? 162 GLU E CB  1 
ATOM   6664 C  CG  . GLU E 1 162 ? 54.837  -52.686 50.699  1.00 48.09  ? 162 GLU E CG  1 
ATOM   6665 C  CD  . GLU E 1 162 ? 54.775  -51.378 51.477  1.00 47.39  ? 162 GLU E CD  1 
ATOM   6666 O  OE1 . GLU E 1 162 ? 55.848  -50.816 51.774  1.00 52.31  ? 162 GLU E OE1 1 
ATOM   6667 O  OE2 . GLU E 1 162 ? 53.652  -50.902 51.773  1.00 49.72  ? 162 GLU E OE2 1 
ATOM   6668 N  N   . CYS E 1 163 ? 57.987  -54.807 49.330  1.00 46.77  ? 163 CYS E N   1 
ATOM   6669 C  CA  . CYS E 1 163 ? 58.854  -54.686 48.157  1.00 45.94  ? 163 CYS E CA  1 
ATOM   6670 C  C   . CYS E 1 163 ? 58.568  -55.759 47.118  1.00 52.37  ? 163 CYS E C   1 
ATOM   6671 O  O   . CYS E 1 163 ? 58.481  -55.470 45.916  1.00 46.65  ? 163 CYS E O   1 
ATOM   6672 C  CB  . CYS E 1 163 ? 60.318  -54.776 48.570  1.00 45.12  ? 163 CYS E CB  1 
ATOM   6673 S  SG  . CYS E 1 163 ? 61.035  -53.221 49.040  1.00 59.12  ? 163 CYS E SG  1 
ATOM   6674 N  N   . MET E 1 164 ? 58.502  -57.021 47.545  1.00 47.68  ? 164 MET E N   1 
ATOM   6675 C  CA  . MET E 1 164 ? 58.302  -58.068 46.553  1.00 49.84  ? 164 MET E CA  1 
ATOM   6676 C  C   . MET E 1 164 ? 56.928  -57.951 45.921  1.00 49.74  ? 164 MET E C   1 
ATOM   6677 O  O   . MET E 1 164 ? 56.772  -58.191 44.720  1.00 48.73  ? 164 MET E O   1 
ATOM   6678 C  CB  . MET E 1 164 ? 58.516  -59.454 47.172  1.00 55.82  ? 164 MET E CB  1 
ATOM   6679 C  CG  . MET E 1 164 ? 59.824  -59.594 47.971  1.00 59.70  ? 164 MET E CG  1 
ATOM   6680 S  SD  . MET E 1 164 ? 61.351  -59.616 46.984  1.00 92.32  ? 164 MET E SD  1 
ATOM   6681 C  CE  . MET E 1 164 ? 61.813  -57.871 46.883  1.00 68.68  ? 164 MET E CE  1 
ATOM   6682 N  N   . PHE E 1 165 ? 55.933  -57.545 46.704  1.00 49.51  ? 165 PHE E N   1 
ATOM   6683 C  CA  . PHE E 1 165 ? 54.618  -57.304 46.133  1.00 45.38  ? 165 PHE E CA  1 
ATOM   6684 C  C   . PHE E 1 165 ? 54.665  -56.187 45.095  1.00 49.78  ? 165 PHE E C   1 
ATOM   6685 O  O   . PHE E 1 165 ? 54.093  -56.312 44.009  1.00 48.97  ? 165 PHE E O   1 
ATOM   6686 C  CB  . PHE E 1 165 ? 53.637  -56.971 47.243  1.00 45.11  ? 165 PHE E CB  1 
ATOM   6687 C  CG  . PHE E 1 165 ? 52.246  -56.814 46.767  1.00 48.58  ? 165 PHE E CG  1 
ATOM   6688 C  CD1 . PHE E 1 165 ? 51.780  -55.568 46.344  1.00 44.54  ? 165 PHE E CD1 1 
ATOM   6689 C  CD2 . PHE E 1 165 ? 51.395  -57.912 46.726  1.00 43.79  ? 165 PHE E CD2 1 
ATOM   6690 C  CE1 . PHE E 1 165 ? 50.485  -55.415 45.893  1.00 41.90  ? 165 PHE E CE1 1 
ATOM   6691 C  CE2 . PHE E 1 165 ? 50.093  -57.769 46.283  1.00 47.53  ? 165 PHE E CE2 1 
ATOM   6692 C  CZ  . PHE E 1 165 ? 49.634  -56.516 45.865  1.00 45.39  ? 165 PHE E CZ  1 
ATOM   6693 N  N   . ASP E 1 166 ? 55.347  -55.083 45.413  1.00 49.68  ? 166 ASP E N   1 
ATOM   6694 C  CA  . ASP E 1 166 ? 55.463  -53.997 44.449  1.00 49.37  ? 166 ASP E CA  1 
ATOM   6695 C  C   . ASP E 1 166 ? 56.177  -54.435 43.170  1.00 53.39  ? 166 ASP E C   1 
ATOM   6696 O  O   . ASP E 1 166 ? 55.865  -53.934 42.083  1.00 56.74  ? 166 ASP E O   1 
ATOM   6697 C  CB  . ASP E 1 166 ? 56.192  -52.814 45.082  1.00 47.69  ? 166 ASP E CB  1 
ATOM   6698 C  CG  . ASP E 1 166 ? 56.192  -51.607 44.191  1.00 43.50  ? 166 ASP E CG  1 
ATOM   6699 O  OD1 . ASP E 1 166 ? 55.175  -50.887 44.192  1.00 42.35  ? 166 ASP E OD1 1 
ATOM   6700 O  OD2 . ASP E 1 166 ? 57.196  -51.387 43.479  1.00 49.50  ? 166 ASP E OD2 1 
ATOM   6701 N  N   . LYS E 1 167 ? 57.140  -55.356 43.272  1.00 51.28  ? 167 LYS E N   1 
ATOM   6702 C  CA  . LYS E 1 167 ? 57.830  -55.825 42.077  1.00 49.64  ? 167 LYS E CA  1 
ATOM   6703 C  C   . LYS E 1 167 ? 56.913  -56.693 41.221  1.00 55.29  ? 167 LYS E C   1 
ATOM   6704 O  O   . LYS E 1 167 ? 56.869  -56.536 39.993  1.00 54.73  ? 167 LYS E O   1 
ATOM   6705 C  CB  . LYS E 1 167 ? 59.102  -56.585 42.471  1.00 57.01  ? 167 LYS E CB  1 
ATOM   6706 C  CG  . LYS E 1 167 ? 59.983  -56.968 41.277  1.00 60.62  ? 167 LYS E CG  1 
ATOM   6707 C  CD  . LYS E 1 167 ? 61.229  -57.745 41.683  1.00 66.82  ? 167 LYS E CD  1 
ATOM   6708 C  CE  . LYS E 1 167 ? 61.747  -58.586 40.514  1.00 73.61  ? 167 LYS E CE  1 
ATOM   6709 N  NZ  . LYS E 1 167 ? 61.727  -57.824 39.220  1.00 69.17  ? 167 LYS E NZ  1 
ATOM   6710 N  N   . GLU E 1 168 ? 56.167  -57.612 41.855  1.00 52.42  ? 168 GLU E N   1 
ATOM   6711 C  CA  . GLU E 1 168 ? 55.257  -58.493 41.129  1.00 57.34  ? 168 GLU E CA  1 
ATOM   6712 C  C   . GLU E 1 168 ? 54.045  -57.741 40.605  1.00 59.12  ? 168 GLU E C   1 
ATOM   6713 O  O   . GLU E 1 168 ? 53.328  -58.254 39.740  1.00 58.60  ? 168 GLU E O   1 
ATOM   6714 C  CB  . GLU E 1 168 ? 54.810  -59.657 42.020  1.00 52.34  ? 168 GLU E CB  1 
ATOM   6715 C  CG  . GLU E 1 168 ? 55.857  -60.753 42.167  1.00 60.35  ? 168 GLU E CG  1 
ATOM   6716 C  CD  . GLU E 1 168 ? 55.554  -61.728 43.313  1.00 74.39  ? 168 GLU E CD  1 
ATOM   6717 O  OE1 . GLU E 1 168 ? 54.394  -62.199 43.443  1.00 62.73  ? 168 GLU E OE1 1 
ATOM   6718 O  OE2 . GLU E 1 168 ? 56.496  -62.036 44.082  1.00 79.72  ? 168 GLU E OE2 1 
ATOM   6719 N  N   . LEU E 1 169 ? 53.794  -56.547 41.127  1.00 58.95  ? 169 LEU E N   1 
ATOM   6720 C  CA  . LEU E 1 169 ? 52.802  -55.677 40.517  1.00 62.32  ? 169 LEU E CA  1 
ATOM   6721 C  C   . LEU E 1 169 ? 53.332  -55.102 39.217  1.00 69.46  ? 169 LEU E C   1 
ATOM   6722 O  O   . LEU E 1 169 ? 52.616  -55.067 38.207  1.00 71.33  ? 169 LEU E O   1 
ATOM   6723 C  CB  . LEU E 1 169 ? 52.446  -54.554 41.481  1.00 53.12  ? 169 LEU E CB  1 
ATOM   6724 C  CG  . LEU E 1 169 ? 50.994  -54.205 41.709  1.00 52.79  ? 169 LEU E CG  1 
ATOM   6725 C  CD1 . LEU E 1 169 ? 50.190  -55.465 41.878  1.00 51.28  ? 169 LEU E CD1 1 
ATOM   6726 C  CD2 . LEU E 1 169 ? 50.939  -53.378 42.977  1.00 53.65  ? 169 LEU E CD2 1 
ATOM   6727 N  N   . ASN E 1 170 ? 54.598  -54.671 39.225  1.00 68.96  ? 170 ASN E N   1 
ATOM   6728 C  CA  . ASN E 1 170 ? 55.196  -53.926 38.117  1.00 74.64  ? 170 ASN E CA  1 
ATOM   6729 C  C   . ASN E 1 170 ? 55.270  -54.794 36.862  1.00 80.58  ? 170 ASN E C   1 
ATOM   6730 O  O   . ASN E 1 170 ? 55.346  -56.033 36.955  1.00 77.66  ? 170 ASN E O   1 
ATOM   6731 C  CB  . ASN E 1 170 ? 56.594  -53.404 38.505  1.00 64.47  ? 170 ASN E CB  1 
ATOM   6732 C  CG  . ASN E 1 170 ? 56.775  -51.909 38.198  1.00 68.39  ? 170 ASN E CG  1 
ATOM   6733 O  OD1 . ASN E 1 170 ? 55.979  -51.317 37.458  1.00 65.24  ? 170 ASN E OD1 1 
ATOM   6734 N  ND2 . ASN E 1 170 ? 57.835  -51.301 38.752  1.00 54.73  ? 170 ASN E ND2 1 
ATOM   6735 O  OXT . ASN E 1 170 ? 55.237  -54.264 35.744  1.00 78.75  ? 170 ASN E OXT 1 
ATOM   6736 N  N   . TYR F 1 9   ? -17.770 -51.563 62.493  1.00 78.38  ? 9   TYR F N   1 
ATOM   6737 C  CA  . TYR F 1 9   ? -16.991 -51.899 63.690  1.00 90.95  ? 9   TYR F CA  1 
ATOM   6738 C  C   . TYR F 1 9   ? -17.069 -53.389 64.070  1.00 90.63  ? 9   TYR F C   1 
ATOM   6739 O  O   . TYR F 1 9   ? -18.037 -53.823 64.706  1.00 85.19  ? 9   TYR F O   1 
ATOM   6740 C  CB  . TYR F 1 9   ? -17.453 -51.046 64.869  1.00 86.43  ? 9   TYR F CB  1 
ATOM   6741 C  CG  . TYR F 1 9   ? -16.528 -51.094 66.066  1.00 89.02  ? 9   TYR F CG  1 
ATOM   6742 C  CD1 . TYR F 1 9   ? -15.187 -50.726 65.950  1.00 86.38  ? 9   TYR F CD1 1 
ATOM   6743 C  CD2 . TYR F 1 9   ? -16.998 -51.484 67.322  1.00 86.08  ? 9   TYR F CD2 1 
ATOM   6744 C  CE1 . TYR F 1 9   ? -14.340 -50.759 67.047  1.00 79.17  ? 9   TYR F CE1 1 
ATOM   6745 C  CE2 . TYR F 1 9   ? -16.156 -51.512 68.431  1.00 76.51  ? 9   TYR F CE2 1 
ATOM   6746 C  CZ  . TYR F 1 9   ? -14.834 -51.145 68.282  1.00 75.05  ? 9   TYR F CZ  1 
ATOM   6747 O  OH  . TYR F 1 9   ? -14.003 -51.174 69.371  1.00 70.92  ? 9   TYR F OH  1 
ATOM   6748 N  N   . HIS F 1 10  ? -16.024 -54.144 63.714  1.00 91.16  ? 10  HIS F N   1 
ATOM   6749 C  CA  . HIS F 1 10  ? -16.020 -55.604 63.766  1.00 91.80  ? 10  HIS F CA  1 
ATOM   6750 C  C   . HIS F 1 10  ? -15.840 -56.135 65.193  1.00 93.12  ? 10  HIS F C   1 
ATOM   6751 O  O   . HIS F 1 10  ? -15.320 -55.456 66.084  1.00 89.89  ? 10  HIS F O   1 
ATOM   6752 C  CB  . HIS F 1 10  ? -14.919 -56.172 62.864  1.00 91.65  ? 10  HIS F CB  1 
ATOM   6753 C  CG  . HIS F 1 10  ? -15.080 -57.632 62.568  1.00 91.26  ? 10  HIS F CG  1 
ATOM   6754 N  ND1 . HIS F 1 10  ? -14.456 -58.616 63.306  1.00 91.08  ? 10  HIS F ND1 1 
ATOM   6755 C  CD2 . HIS F 1 10  ? -15.807 -58.275 61.623  1.00 85.96  ? 10  HIS F CD2 1 
ATOM   6756 C  CE1 . HIS F 1 10  ? -14.788 -59.801 62.827  1.00 89.53  ? 10  HIS F CE1 1 
ATOM   6757 N  NE2 . HIS F 1 10  ? -15.606 -59.621 61.805  1.00 91.08  ? 10  HIS F NE2 1 
ATOM   6758 N  N   . GLU F 1 11  ? -16.225 -57.403 65.375  1.00 93.01  ? 11  GLU F N   1 
ATOM   6759 C  CA  . GLU F 1 11  ? -16.510 -57.943 66.702  1.00 89.11  ? 11  GLU F CA  1 
ATOM   6760 C  C   . GLU F 1 11  ? -15.255 -58.114 67.556  1.00 92.11  ? 11  GLU F C   1 
ATOM   6761 O  O   . GLU F 1 11  ? -15.227 -57.666 68.709  1.00 93.50  ? 11  GLU F O   1 
ATOM   6762 C  CB  . GLU F 1 11  ? -17.251 -59.268 66.572  1.00 93.14  ? 11  GLU F CB  1 
ATOM   6763 C  CG  . GLU F 1 11  ? -17.649 -59.869 67.898  1.00 100.74 ? 11  GLU F CG  1 
ATOM   6764 C  CD  . GLU F 1 11  ? -17.339 -61.349 67.967  1.00 104.50 ? 11  GLU F CD  1 
ATOM   6765 O  OE1 . GLU F 1 11  ? -17.174 -61.963 66.888  1.00 107.57 ? 11  GLU F OE1 1 
ATOM   6766 O  OE2 . GLU F 1 11  ? -17.266 -61.895 69.094  1.00 103.16 ? 11  GLU F OE2 1 
ATOM   6767 N  N   . ASP F 1 12  ? -14.218 -58.782 67.044  1.00 95.56  ? 12  ASP F N   1 
ATOM   6768 C  CA  . ASP F 1 12  ? -12.993 -58.938 67.828  1.00 89.11  ? 12  ASP F CA  1 
ATOM   6769 C  C   . ASP F 1 12  ? -11.892 -57.953 67.439  1.00 83.66  ? 12  ASP F C   1 
ATOM   6770 O  O   . ASP F 1 12  ? -10.765 -58.083 67.930  1.00 79.78  ? 12  ASP F O   1 
ATOM   6771 C  CB  . ASP F 1 12  ? -12.479 -60.381 67.764  1.00 83.26  ? 12  ASP F CB  1 
ATOM   6772 C  CG  . ASP F 1 12  ? -12.603 -60.979 66.389  1.00 95.97  ? 12  ASP F CG  1 
ATOM   6773 O  OD1 . ASP F 1 12  ? -12.523 -60.220 65.391  1.00 86.57  ? 12  ASP F OD1 1 
ATOM   6774 O  OD2 . ASP F 1 12  ? -12.811 -62.212 66.319  1.00 98.82  ? 12  ASP F OD2 1 
ATOM   6775 N  N   . CYS F 1 13  ? -12.184 -56.980 66.567  1.00 76.93  ? 13  CYS F N   1 
ATOM   6776 C  CA  . CYS F 1 13  ? -11.624 -55.650 66.772  1.00 73.53  ? 13  CYS F CA  1 
ATOM   6777 C  C   . CYS F 1 13  ? -11.919 -55.190 68.197  1.00 79.04  ? 13  CYS F C   1 
ATOM   6778 O  O   . CYS F 1 13  ? -11.028 -54.726 68.917  1.00 79.40  ? 13  CYS F O   1 
ATOM   6779 C  CB  . CYS F 1 13  ? -12.215 -54.647 65.773  1.00 83.53  ? 13  CYS F CB  1 
ATOM   6780 S  SG  . CYS F 1 13  ? -11.254 -54.237 64.287  1.00 85.34  ? 13  CYS F SG  1 
ATOM   6781 N  N   . GLU F 1 14  ? -13.181 -55.328 68.623  1.00 79.70  ? 14  GLU F N   1 
ATOM   6782 C  CA  . GLU F 1 14  ? -13.586 -54.896 69.957  1.00 70.78  ? 14  GLU F CA  1 
ATOM   6783 C  C   . GLU F 1 14  ? -12.985 -55.784 71.036  1.00 68.54  ? 14  GLU F C   1 
ATOM   6784 O  O   . GLU F 1 14  ? -12.639 -55.295 72.120  1.00 65.71  ? 14  GLU F O   1 
ATOM   6785 C  CB  . GLU F 1 14  ? -15.113 -54.868 70.051  1.00 67.78  ? 14  GLU F CB  1 
ATOM   6786 C  CG  . GLU F 1 14  ? -15.708 -55.374 71.360  1.00 66.72  ? 14  GLU F CG  1 
ATOM   6787 C  CD  . GLU F 1 14  ? -17.205 -55.076 71.466  1.00 67.67  ? 14  GLU F CD  1 
ATOM   6788 O  OE1 . GLU F 1 14  ? -17.864 -54.993 70.405  1.00 72.70  ? 14  GLU F OE1 1 
ATOM   6789 O  OE2 . GLU F 1 14  ? -17.726 -54.943 72.599  1.00 59.44  ? 14  GLU F OE2 1 
ATOM   6790 N  N   . ALA F 1 15  ? -12.831 -57.086 70.757  1.00 67.90  ? 15  ALA F N   1 
ATOM   6791 C  CA  . ALA F 1 15  ? -12.224 -57.981 71.743  1.00 59.98  ? 15  ALA F CA  1 
ATOM   6792 C  C   . ALA F 1 15  ? -10.726 -57.730 71.901  1.00 65.60  ? 15  ALA F C   1 
ATOM   6793 O  O   . ALA F 1 15  ? -10.185 -57.850 73.010  1.00 62.37  ? 15  ALA F O   1 
ATOM   6794 C  CB  . ALA F 1 15  ? -12.465 -59.435 71.364  1.00 53.63  ? 15  ALA F CB  1 
ATOM   6795 N  N   . SER F 1 16  ? -10.033 -57.393 70.822  1.00 57.26  ? 16  SER F N   1 
ATOM   6796 C  CA  . SER F 1 16  ? -8.613  -57.147 70.962  1.00 62.55  ? 16  SER F CA  1 
ATOM   6797 C  C   . SER F 1 16  ? -8.311  -55.722 71.407  1.00 58.88  ? 16  SER F C   1 
ATOM   6798 O  O   . SER F 1 16  ? -7.204  -55.467 71.883  1.00 57.11  ? 16  SER F O   1 
ATOM   6799 C  CB  . SER F 1 16  ? -7.883  -57.481 69.657  1.00 66.35  ? 16  SER F CB  1 
ATOM   6800 O  OG  . SER F 1 16  ? -8.033  -56.452 68.708  1.00 64.12  ? 16  SER F OG  1 
ATOM   6801 N  N   . ILE F 1 17  ? -9.261  -54.791 71.271  1.00 63.89  ? 17  ILE F N   1 
ATOM   6802 C  CA  . ILE F 1 17  ? -9.187  -53.547 72.038  1.00 52.74  ? 17  ILE F CA  1 
ATOM   6803 C  C   . ILE F 1 17  ? -9.116  -53.867 73.527  1.00 56.96  ? 17  ILE F C   1 
ATOM   6804 O  O   . ILE F 1 17  ? -8.266  -53.342 74.256  1.00 55.57  ? 17  ILE F O   1 
ATOM   6805 C  CB  . ILE F 1 17  ? -10.391 -52.639 71.732  1.00 50.62  ? 17  ILE F CB  1 
ATOM   6806 C  CG1 . ILE F 1 17  ? -10.312 -52.032 70.323  1.00 63.60  ? 17  ILE F CG1 1 
ATOM   6807 C  CG2 . ILE F 1 17  ? -10.512 -51.547 72.798  1.00 49.81  ? 17  ILE F CG2 1 
ATOM   6808 C  CD1 . ILE F 1 17  ? -9.668  -50.657 70.251  1.00 62.80  ? 17  ILE F CD1 1 
ATOM   6809 N  N   . ASN F 1 18  ? -10.010 -54.748 73.998  1.00 51.79  ? 18  ASN F N   1 
ATOM   6810 C  CA  . ASN F 1 18  ? -9.992  -55.133 75.402  1.00 52.31  ? 18  ASN F CA  1 
ATOM   6811 C  C   . ASN F 1 18  ? -8.665  -55.784 75.783  1.00 51.83  ? 18  ASN F C   1 
ATOM   6812 O  O   . ASN F 1 18  ? -8.194  -55.597 76.910  1.00 48.10  ? 18  ASN F O   1 
ATOM   6813 C  CB  . ASN F 1 18  ? -11.181 -56.045 75.719  1.00 49.53  ? 18  ASN F CB  1 
ATOM   6814 C  CG  . ASN F 1 18  ? -12.512 -55.274 75.792  1.00 52.33  ? 18  ASN F CG  1 
ATOM   6815 O  OD1 . ASN F 1 18  ? -12.554 -54.126 76.222  1.00 52.49  ? 18  ASN F OD1 1 
ATOM   6816 N  ND2 . ASN F 1 18  ? -13.590 -55.905 75.359  1.00 48.51  ? 18  ASN F ND2 1 
ATOM   6817 N  N   . LYS F 1 19  ? -8.032  -56.513 74.856  1.00 54.52  ? 19  LYS F N   1 
ATOM   6818 C  CA  . LYS F 1 19  ? -6.662  -56.980 75.085  1.00 55.08  ? 19  LYS F CA  1 
ATOM   6819 C  C   . LYS F 1 19  ? -5.727  -55.802 75.330  1.00 51.42  ? 19  LYS F C   1 
ATOM   6820 O  O   . LYS F 1 19  ? -5.006  -55.761 76.338  1.00 48.45  ? 19  LYS F O   1 
ATOM   6821 C  CB  . LYS F 1 19  ? -6.163  -57.812 73.896  1.00 53.76  ? 19  LYS F CB  1 
ATOM   6822 C  CG  . LYS F 1 19  ? -6.255  -59.332 74.074  1.00 61.47  ? 19  LYS F CG  1 
ATOM   6823 C  CD  . LYS F 1 19  ? -6.851  -60.025 72.831  1.00 75.61  ? 19  LYS F CD  1 
ATOM   6824 C  CE  . LYS F 1 19  ? -7.245  -61.485 73.124  1.00 69.16  ? 19  LYS F CE  1 
ATOM   6825 N  NZ  . LYS F 1 19  ? -7.974  -62.138 71.998  1.00 59.76  ? 19  LYS F NZ  1 
ATOM   6826 N  N   . GLN F 1 20  ? -5.767  -54.810 74.434  1.00 47.19  ? 20  GLN F N   1 
ATOM   6827 C  CA  . GLN F 1 20  ? -4.865  -53.670 74.530  1.00 47.26  ? 20  GLN F CA  1 
ATOM   6828 C  C   . GLN F 1 20  ? -5.087  -52.876 75.816  1.00 49.51  ? 20  GLN F C   1 
ATOM   6829 O  O   . GLN F 1 20  ? -4.123  -52.390 76.417  1.00 49.69  ? 20  GLN F O   1 
ATOM   6830 C  CB  . GLN F 1 20  ? -5.029  -52.767 73.306  1.00 48.08  ? 20  GLN F CB  1 
ATOM   6831 C  CG  . GLN F 1 20  ? -3.839  -51.856 73.048  1.00 48.14  ? 20  GLN F CG  1 
ATOM   6832 C  CD  . GLN F 1 20  ? -2.558  -52.642 72.791  1.00 56.16  ? 20  GLN F CD  1 
ATOM   6833 O  OE1 . GLN F 1 20  ? -2.593  -53.787 72.317  1.00 50.31  ? 20  GLN F OE1 1 
ATOM   6834 N  NE2 . GLN F 1 20  ? -1.420  -52.037 73.123  1.00 53.58  ? 20  GLN F NE2 1 
ATOM   6835 N  N   . ILE F 1 21  ? -6.342  -52.731 76.259  1.00 46.92  ? 21  ILE F N   1 
ATOM   6836 C  CA  . ILE F 1 21  ? -6.596  -52.042 77.526  1.00 43.48  ? 21  ILE F CA  1 
ATOM   6837 C  C   . ILE F 1 21  ? -5.894  -52.760 78.669  1.00 39.78  ? 21  ILE F C   1 
ATOM   6838 O  O   . ILE F 1 21  ? -5.264  -52.129 79.528  1.00 42.76  ? 21  ILE F O   1 
ATOM   6839 C  CB  . ILE F 1 21  ? -8.104  -51.922 77.803  1.00 46.68  ? 21  ILE F CB  1 
ATOM   6840 C  CG1 . ILE F 1 21  ? -8.768  -50.947 76.829  1.00 42.38  ? 21  ILE F CG1 1 
ATOM   6841 C  CG2 . ILE F 1 21  ? -8.345  -51.549 79.309  1.00 34.44  ? 21  ILE F CG2 1 
ATOM   6842 C  CD1 . ILE F 1 21  ? -10.264 -51.208 76.653  1.00 46.00  ? 21  ILE F CD1 1 
ATOM   6843 N  N   . ASN F 1 22  ? -6.012  -54.090 78.711  1.00 37.47  ? 22  ASN F N   1 
ATOM   6844 C  CA  . ASN F 1 22  ? -5.345  -54.848 79.763  1.00 37.36  ? 22  ASN F CA  1 
ATOM   6845 C  C   . ASN F 1 22  ? -3.838  -54.688 79.662  1.00 39.39  ? 22  ASN F C   1 
ATOM   6846 O  O   . ASN F 1 22  ? -3.152  -54.598 80.680  1.00 39.02  ? 22  ASN F O   1 
ATOM   6847 C  CB  . ASN F 1 22  ? -5.731  -56.321 79.690  1.00 37.01  ? 22  ASN F CB  1 
ATOM   6848 C  CG  . ASN F 1 22  ? -5.277  -57.101 80.906  1.00 35.85  ? 22  ASN F CG  1 
ATOM   6849 O  OD1 . ASN F 1 22  ? -4.148  -57.575 80.963  1.00 36.47  ? 22  ASN F OD1 1 
ATOM   6850 N  ND2 . ASN F 1 22  ? -6.159  -57.238 81.891  1.00 37.37  ? 22  ASN F ND2 1 
ATOM   6851 N  N   . MET F 1 23  ? -3.314  -54.608 78.438  1.00 41.70  ? 23  MET F N   1 
ATOM   6852 C  CA  . MET F 1 23  ? -1.874  -54.477 78.240  1.00 43.84  ? 23  MET F CA  1 
ATOM   6853 C  C   . MET F 1 23  ? -1.347  -53.163 78.824  1.00 47.96  ? 23  MET F C   1 
ATOM   6854 O  O   . MET F 1 23  ? -0.354  -53.157 79.567  1.00 42.06  ? 23  MET F O   1 
ATOM   6855 C  CB  . MET F 1 23  ? -1.554  -54.587 76.746  1.00 48.54  ? 23  MET F CB  1 
ATOM   6856 C  CG  . MET F 1 23  ? -0.077  -54.589 76.396  1.00 51.09  ? 23  MET F CG  1 
ATOM   6857 S  SD  . MET F 1 23  ? 0.725   -56.139 76.846  1.00 79.47  ? 23  MET F SD  1 
ATOM   6858 C  CE  . MET F 1 23  ? 0.016   -57.239 75.612  1.00 61.85  ? 23  MET F CE  1 
ATOM   6859 N  N   . GLU F 1 24  ? -2.007  -52.037 78.506  1.00 42.44  ? 24  GLU F N   1 
ATOM   6860 C  CA  . GLU F 1 24  ? -1.578  -50.747 79.051  1.00 45.92  ? 24  GLU F CA  1 
ATOM   6861 C  C   . GLU F 1 24  ? -1.730  -50.696 80.570  1.00 40.72  ? 24  GLU F C   1 
ATOM   6862 O  O   . GLU F 1 24  ? -0.891  -50.112 81.266  1.00 34.21  ? 24  GLU F O   1 
ATOM   6863 C  CB  . GLU F 1 24  ? -2.363  -49.606 78.405  1.00 48.14  ? 24  GLU F CB  1 
ATOM   6864 C  CG  . GLU F 1 24  ? -2.604  -49.770 76.914  1.00 55.43  ? 24  GLU F CG  1 
ATOM   6865 C  CD  . GLU F 1 24  ? -1.391  -49.418 76.075  1.00 63.87  ? 24  GLU F CD  1 
ATOM   6866 O  OE1 . GLU F 1 24  ? -0.360  -49.039 76.671  1.00 59.20  ? 24  GLU F OE1 1 
ATOM   6867 O  OE2 . GLU F 1 24  ? -1.463  -49.527 74.823  1.00 72.32  ? 24  GLU F OE2 1 
ATOM   6868 N  N   . LEU F 1 25  ? -2.801  -51.294 81.101  1.00 41.49  ? 25  LEU F N   1 
ATOM   6869 C  CA  . LEU F 1 25  ? -2.969  -51.349 82.550  1.00 39.43  ? 25  LEU F CA  1 
ATOM   6870 C  C   . LEU F 1 25  ? -1.862  -52.172 83.178  1.00 40.53  ? 25  LEU F C   1 
ATOM   6871 O  O   . LEU F 1 25  ? -1.310  -51.797 84.223  1.00 37.80  ? 25  LEU F O   1 
ATOM   6872 C  CB  . LEU F 1 25  ? -4.334  -51.936 82.906  1.00 39.64  ? 25  LEU F CB  1 
ATOM   6873 C  CG  . LEU F 1 25  ? -5.510  -51.019 82.589  1.00 36.35  ? 25  LEU F CG  1 
ATOM   6874 C  CD1 . LEU F 1 25  ? -6.842  -51.758 82.759  1.00 40.22  ? 25  LEU F CD1 1 
ATOM   6875 C  CD2 . LEU F 1 25  ? -5.447  -49.770 83.465  1.00 32.76  ? 25  LEU F CD2 1 
ATOM   6876 N  N   . TYR F 1 26  ? -1.522  -53.296 82.540  1.00 38.69  ? 26  TYR F N   1 
ATOM   6877 C  CA  . TYR F 1 26  ? -0.379  -54.092 82.968  1.00 40.76  ? 26  TYR F CA  1 
ATOM   6878 C  C   . TYR F 1 26  ? 0.885   -53.245 82.984  1.00 39.90  ? 26  TYR F C   1 
ATOM   6879 O  O   . TYR F 1 26  ? 1.618   -53.201 83.989  1.00 34.65  ? 26  TYR F O   1 
ATOM   6880 C  CB  . TYR F 1 26  ? -0.197  -55.298 82.038  1.00 36.75  ? 26  TYR F CB  1 
ATOM   6881 C  CG  . TYR F 1 26  ? 1.041   -56.091 82.365  1.00 32.52  ? 26  TYR F CG  1 
ATOM   6882 C  CD1 . TYR F 1 26  ? 1.192   -56.676 83.609  1.00 34.78  ? 26  TYR F CD1 1 
ATOM   6883 C  CD2 . TYR F 1 26  ? 2.081   -56.223 81.450  1.00 37.25  ? 26  TYR F CD2 1 
ATOM   6884 C  CE1 . TYR F 1 26  ? 2.346   -57.392 83.938  1.00 36.49  ? 26  TYR F CE1 1 
ATOM   6885 C  CE2 . TYR F 1 26  ? 3.236   -56.948 81.768  1.00 32.41  ? 26  TYR F CE2 1 
ATOM   6886 C  CZ  . TYR F 1 26  ? 3.352   -57.531 83.008  1.00 32.03  ? 26  TYR F CZ  1 
ATOM   6887 O  OH  . TYR F 1 26  ? 4.483   -58.240 83.354  1.00 46.90  ? 26  TYR F OH  1 
ATOM   6888 N  N   . ALA F 1 27  ? 1.136   -52.541 81.880  1.00 36.74  ? 27  ALA F N   1 
ATOM   6889 C  CA  . ALA F 1 27  ? 2.358   -51.762 81.762  1.00 38.08  ? 27  ALA F CA  1 
ATOM   6890 C  C   . ALA F 1 27  ? 2.404   -50.668 82.811  1.00 36.83  ? 27  ALA F C   1 
ATOM   6891 O  O   . ALA F 1 27  ? 3.474   -50.383 83.360  1.00 38.71  ? 27  ALA F O   1 
ATOM   6892 C  CB  . ALA F 1 27  ? 2.478   -51.167 80.360  1.00 35.97  ? 27  ALA F CB  1 
ATOM   6893 N  N   . SER F 1 28  ? 1.253   -50.044 83.099  1.00 34.86  ? 28  SER F N   1 
ATOM   6894 C  CA  . SER F 1 28  ? 1.190   -49.030 84.152  1.00 38.10  ? 28  SER F CA  1 
ATOM   6895 C  C   . SER F 1 28  ? 1.543   -49.619 85.509  1.00 38.45  ? 28  SER F C   1 
ATOM   6896 O  O   . SER F 1 28  ? 2.201   -48.968 86.334  1.00 33.49  ? 28  SER F O   1 
ATOM   6897 C  CB  . SER F 1 28  ? -0.206  -48.425 84.219  1.00 35.82  ? 28  SER F CB  1 
ATOM   6898 O  OG  . SER F 1 28  ? -0.307  -47.595 85.358  1.00 33.62  ? 28  SER F OG  1 
ATOM   6899 N  N   . TYR F 1 29  ? 1.093   -50.851 85.752  1.00 33.43  ? 29  TYR F N   1 
ATOM   6900 C  CA  . TYR F 1 29  ? 1.372   -51.541 87.000  1.00 35.41  ? 29  TYR F CA  1 
ATOM   6901 C  C   . TYR F 1 29  ? 2.866   -51.854 87.129  1.00 37.28  ? 29  TYR F C   1 
ATOM   6902 O  O   . TYR F 1 29  ? 3.464   -51.632 88.191  1.00 33.98  ? 29  TYR F O   1 
ATOM   6903 C  CB  . TYR F 1 29  ? 0.513   -52.811 87.057  1.00 32.26  ? 29  TYR F CB  1 
ATOM   6904 C  CG  . TYR F 1 29  ? 0.346   -53.430 88.418  1.00 33.98  ? 29  TYR F CG  1 
ATOM   6905 C  CD1 . TYR F 1 29  ? 0.626   -52.716 89.589  1.00 37.05  ? 29  TYR F CD1 1 
ATOM   6906 C  CD2 . TYR F 1 29  ? -0.091  -54.746 88.543  1.00 37.11  ? 29  TYR F CD2 1 
ATOM   6907 C  CE1 . TYR F 1 29  ? 0.460   -53.300 90.849  1.00 34.93  ? 29  TYR F CE1 1 
ATOM   6908 C  CE2 . TYR F 1 29  ? -0.253  -55.337 89.789  1.00 38.46  ? 29  TYR F CE2 1 
ATOM   6909 C  CZ  . TYR F 1 29  ? 0.023   -54.617 90.937  1.00 37.01  ? 29  TYR F CZ  1 
ATOM   6910 O  OH  . TYR F 1 29  ? -0.150  -55.230 92.154  1.00 33.71  ? 29  TYR F OH  1 
ATOM   6911 N  N   . VAL F 1 30  ? 3.489   -52.353 86.049  1.00 32.41  ? 30  VAL F N   1 
ATOM   6912 C  CA  . VAL F 1 30  ? 4.922   -52.654 86.083  1.00 33.98  ? 30  VAL F CA  1 
ATOM   6913 C  C   . VAL F 1 30  ? 5.716   -51.398 86.416  1.00 37.76  ? 30  VAL F C   1 
ATOM   6914 O  O   . VAL F 1 30  ? 6.614   -51.413 87.267  1.00 37.36  ? 30  VAL F O   1 
ATOM   6915 C  CB  . VAL F 1 30  ? 5.399   -53.254 84.744  1.00 37.24  ? 30  VAL F CB  1 
ATOM   6916 C  CG1 . VAL F 1 30  ? 6.939   -53.321 84.716  1.00 34.16  ? 30  VAL F CG1 1 
ATOM   6917 C  CG2 . VAL F 1 30  ? 4.798   -54.609 84.492  1.00 28.85  ? 30  VAL F CG2 1 
ATOM   6918 N  N   . TYR F 1 31  ? 5.417   -50.297 85.721  1.00 35.19  ? 31  TYR F N   1 
ATOM   6919 C  CA  . TYR F 1 31  ? 6.103   -49.037 85.992  1.00 36.22  ? 31  TYR F CA  1 
ATOM   6920 C  C   . TYR F 1 31  ? 5.872   -48.582 87.427  1.00 37.90  ? 31  TYR F C   1 
ATOM   6921 O  O   . TYR F 1 31  ? 6.771   -48.023 88.066  1.00 35.25  ? 31  TYR F O   1 
ATOM   6922 C  CB  . TYR F 1 31  ? 5.629   -47.972 85.016  1.00 32.39  ? 31  TYR F CB  1 
ATOM   6923 C  CG  . TYR F 1 31  ? 6.293   -48.053 83.667  1.00 39.09  ? 31  TYR F CG  1 
ATOM   6924 C  CD1 . TYR F 1 31  ? 7.607   -48.468 83.549  1.00 45.98  ? 31  TYR F CD1 1 
ATOM   6925 C  CD2 . TYR F 1 31  ? 5.612   -47.708 82.514  1.00 41.19  ? 31  TYR F CD2 1 
ATOM   6926 C  CE1 . TYR F 1 31  ? 8.231   -48.534 82.325  1.00 47.37  ? 31  TYR F CE1 1 
ATOM   6927 C  CE2 . TYR F 1 31  ? 6.223   -47.775 81.281  1.00 48.45  ? 31  TYR F CE2 1 
ATOM   6928 C  CZ  . TYR F 1 31  ? 7.534   -48.189 81.194  1.00 51.70  ? 31  TYR F CZ  1 
ATOM   6929 O  OH  . TYR F 1 31  ? 8.156   -48.257 79.975  1.00 50.50  ? 31  TYR F OH  1 
ATOM   6930 N  N   . LEU F 1 32  ? 4.666   -48.805 87.947  1.00 33.13  ? 32  LEU F N   1 
ATOM   6931 C  CA  . LEU F 1 32  ? 4.409   -48.464 89.332  1.00 34.79  ? 32  LEU F CA  1 
ATOM   6932 C  C   . LEU F 1 32  ? 5.334   -49.258 90.249  1.00 40.49  ? 32  LEU F C   1 
ATOM   6933 O  O   . LEU F 1 32  ? 5.971   -48.690 91.149  1.00 36.91  ? 32  LEU F O   1 
ATOM   6934 C  CB  . LEU F 1 32  ? 2.931   -48.706 89.667  1.00 34.07  ? 32  LEU F CB  1 
ATOM   6935 C  CG  . LEU F 1 32  ? 2.520   -48.184 91.053  1.00 41.52  ? 32  LEU F CG  1 
ATOM   6936 C  CD1 . LEU F 1 32  ? 2.452   -46.661 91.034  1.00 34.65  ? 32  LEU F CD1 1 
ATOM   6937 C  CD2 . LEU F 1 32  ? 1.196   -48.786 91.537  1.00 35.72  ? 32  LEU F CD2 1 
ATOM   6938 N  N   . SER F 1 33  ? 5.458   -50.569 90.006  1.00 36.70  ? 33  SER F N   1 
ATOM   6939 C  CA  . SER F 1 33  ? 6.365   -51.362 90.824  1.00 32.63  ? 33  SER F CA  1 
ATOM   6940 C  C   . SER F 1 33  ? 7.808   -50.877 90.673  1.00 33.64  ? 33  SER F C   1 
ATOM   6941 O  O   . SER F 1 33  ? 8.555   -50.829 91.658  1.00 37.54  ? 33  SER F O   1 
ATOM   6942 C  CB  . SER F 1 33  ? 6.241   -52.838 90.468  1.00 32.01  ? 33  SER F CB  1 
ATOM   6943 O  OG  . SER F 1 33  ? 7.475   -53.515 90.667  1.00 34.82  ? 33  SER F OG  1 
ATOM   6944 N  N   . MET F 1 34  ? 8.219   -50.508 89.452  1.00 32.90  ? 34  MET F N   1 
ATOM   6945 C  CA  . MET F 1 34  ? 9.582   -50.012 89.254  1.00 37.47  ? 34  MET F CA  1 
ATOM   6946 C  C   . MET F 1 34  ? 9.802   -48.749 90.069  1.00 40.28  ? 34  MET F C   1 
ATOM   6947 O  O   . MET F 1 34  ? 10.809  -48.621 90.780  1.00 36.12  ? 34  MET F O   1 
ATOM   6948 C  CB  . MET F 1 34  ? 9.855   -49.741 87.776  1.00 32.27  ? 34  MET F CB  1 
ATOM   6949 C  CG  . MET F 1 34  ? 10.036  -51.007 86.962  1.00 40.87  ? 34  MET F CG  1 
ATOM   6950 S  SD  . MET F 1 34  ? 10.470  -50.667 85.246  1.00 41.22  ? 34  MET F SD  1 
ATOM   6951 C  CE  . MET F 1 34  ? 10.707  -52.336 84.631  1.00 37.35  ? 34  MET F CE  1 
ATOM   6952 N  N   . ALA F 1 35  ? 8.824   -47.833 90.012  1.00 35.28  ? 35  ALA F N   1 
ATOM   6953 C  CA  . ALA F 1 35  ? 8.907   -46.561 90.707  1.00 32.88  ? 35  ALA F CA  1 
ATOM   6954 C  C   . ALA F 1 35  ? 9.208   -46.754 92.181  1.00 33.21  ? 35  ALA F C   1 
ATOM   6955 O  O   . ALA F 1 35  ? 10.141  -46.148 92.714  1.00 38.16  ? 35  ALA F O   1 
ATOM   6956 C  CB  . ALA F 1 35  ? 7.605   -45.784 90.515  1.00 38.53  ? 35  ALA F CB  1 
ATOM   6957 N  N   . TYR F 1 36  ? 8.445   -47.604 92.862  1.00 36.42  ? 36  TYR F N   1 
ATOM   6958 C  CA  . TYR F 1 36  ? 8.643   -47.707 94.306  1.00 37.26  ? 36  TYR F CA  1 
ATOM   6959 C  C   . TYR F 1 36  ? 9.756   -48.663 94.681  1.00 38.38  ? 36  TYR F C   1 
ATOM   6960 O  O   . TYR F 1 36  ? 10.183  -48.664 95.841  1.00 40.68  ? 36  TYR F O   1 
ATOM   6961 C  CB  . TYR F 1 36  ? 7.349   -48.113 95.013  1.00 34.22  ? 36  TYR F CB  1 
ATOM   6962 C  CG  . TYR F 1 36  ? 6.405   -46.956 95.077  1.00 41.75  ? 36  TYR F CG  1 
ATOM   6963 C  CD1 . TYR F 1 36  ? 5.654   -46.602 93.959  1.00 41.77  ? 36  TYR F CD1 1 
ATOM   6964 C  CD2 . TYR F 1 36  ? 6.292   -46.175 96.233  1.00 39.71  ? 36  TYR F CD2 1 
ATOM   6965 C  CE1 . TYR F 1 36  ? 4.790   -45.508 93.988  1.00 47.52  ? 36  TYR F CE1 1 
ATOM   6966 C  CE2 . TYR F 1 36  ? 5.433   -45.084 96.272  1.00 43.95  ? 36  TYR F CE2 1 
ATOM   6967 C  CZ  . TYR F 1 36  ? 4.685   -44.756 95.140  1.00 49.63  ? 36  TYR F CZ  1 
ATOM   6968 O  OH  . TYR F 1 36  ? 3.831   -43.681 95.138  1.00 56.51  ? 36  TYR F OH  1 
ATOM   6969 N  N   . TYR F 1 37  ? 10.229  -49.481 93.740  1.00 35.27  ? 37  TYR F N   1 
ATOM   6970 C  CA  . TYR F 1 37  ? 11.461  -50.213 93.990  1.00 35.64  ? 37  TYR F CA  1 
ATOM   6971 C  C   . TYR F 1 37  ? 12.636  -49.244 94.115  1.00 43.48  ? 37  TYR F C   1 
ATOM   6972 O  O   . TYR F 1 37  ? 13.502  -49.412 94.990  1.00 34.15  ? 37  TYR F O   1 
ATOM   6973 C  CB  . TYR F 1 37  ? 11.699  -51.233 92.875  1.00 36.56  ? 37  TYR F CB  1 
ATOM   6974 C  CG  . TYR F 1 37  ? 13.082  -51.825 92.883  1.00 37.29  ? 37  TYR F CG  1 
ATOM   6975 C  CD1 . TYR F 1 37  ? 13.474  -52.730 93.867  1.00 40.50  ? 37  TYR F CD1 1 
ATOM   6976 C  CD2 . TYR F 1 37  ? 14.015  -51.446 91.928  1.00 37.63  ? 37  TYR F CD2 1 
ATOM   6977 C  CE1 . TYR F 1 37  ? 14.764  -53.259 93.884  1.00 41.01  ? 37  TYR F CE1 1 
ATOM   6978 C  CE2 . TYR F 1 37  ? 15.298  -51.962 91.937  1.00 39.15  ? 37  TYR F CE2 1 
ATOM   6979 C  CZ  . TYR F 1 37  ? 15.661  -52.866 92.907  1.00 42.47  ? 37  TYR F CZ  1 
ATOM   6980 O  OH  . TYR F 1 37  ? 16.927  -53.363 92.877  1.00 42.48  ? 37  TYR F OH  1 
ATOM   6981 N  N   . PHE F 1 38  ? 12.660  -48.199 93.273  1.00 38.82  ? 38  PHE F N   1 
ATOM   6982 C  CA  . PHE F 1 38  ? 13.766  -47.248 93.297  1.00 38.59  ? 38  PHE F CA  1 
ATOM   6983 C  C   . PHE F 1 38  ? 13.640  -46.226 94.415  1.00 37.37  ? 38  PHE F C   1 
ATOM   6984 O  O   . PHE F 1 38  ? 14.532  -45.397 94.568  1.00 33.74  ? 38  PHE F O   1 
ATOM   6985 C  CB  . PHE F 1 38  ? 13.895  -46.563 91.936  1.00 40.57  ? 38  PHE F CB  1 
ATOM   6986 C  CG  . PHE F 1 38  ? 14.524  -47.453 90.898  1.00 37.61  ? 38  PHE F CG  1 
ATOM   6987 C  CD1 . PHE F 1 38  ? 15.874  -47.762 90.968  1.00 33.80  ? 38  PHE F CD1 1 
ATOM   6988 C  CD2 . PHE F 1 38  ? 13.762  -48.032 89.910  1.00 32.26  ? 38  PHE F CD2 1 
ATOM   6989 C  CE1 . PHE F 1 38  ? 16.449  -48.606 90.059  1.00 39.11  ? 38  PHE F CE1 1 
ATOM   6990 C  CE2 . PHE F 1 38  ? 14.340  -48.884 88.991  1.00 36.71  ? 38  PHE F CE2 1 
ATOM   6991 C  CZ  . PHE F 1 38  ? 15.682  -49.165 89.056  1.00 40.42  ? 38  PHE F CZ  1 
ATOM   6992 N  N   . GLU F 1 39  ? 12.575  -46.288 95.213  1.00 40.57  ? 39  GLU F N   1 
ATOM   6993 C  CA  . GLU F 1 39  ? 12.465  -45.539 96.459  1.00 42.23  ? 39  GLU F CA  1 
ATOM   6994 C  C   . GLU F 1 39  ? 12.771  -46.387 97.700  1.00 41.27  ? 39  GLU F C   1 
ATOM   6995 O  O   . GLU F 1 39  ? 12.639  -45.893 98.818  1.00 45.11  ? 39  GLU F O   1 
ATOM   6996 C  CB  . GLU F 1 39  ? 11.062  -44.926 96.575  1.00 39.81  ? 39  GLU F CB  1 
ATOM   6997 C  CG  . GLU F 1 39  ? 10.878  -43.692 95.713  1.00 42.86  ? 39  GLU F CG  1 
ATOM   6998 C  CD  . GLU F 1 39  ? 9.543   -42.997 95.922  1.00 47.76  ? 39  GLU F CD  1 
ATOM   6999 O  OE1 . GLU F 1 39  ? 8.806   -43.372 96.864  1.00 43.04  ? 39  GLU F OE1 1 
ATOM   7000 O  OE2 . GLU F 1 39  ? 9.242   -42.052 95.147  1.00 58.72  ? 39  GLU F OE2 1 
ATOM   7001 N  N   . ARG F 1 40  ? 13.147  -47.652 97.536  1.00 42.81  ? 40  ARG F N   1 
ATOM   7002 C  CA  . ARG F 1 40  ? 13.619  -48.441 98.666  1.00 39.78  ? 40  ARG F CA  1 
ATOM   7003 C  C   . ARG F 1 40  ? 14.837  -47.766 99.307  1.00 44.78  ? 40  ARG F C   1 
ATOM   7004 O  O   . ARG F 1 40  ? 15.657  -47.132 98.629  1.00 43.48  ? 40  ARG F O   1 
ATOM   7005 C  CB  . ARG F 1 40  ? 13.987  -49.850 98.197  1.00 43.87  ? 40  ARG F CB  1 
ATOM   7006 C  CG  . ARG F 1 40  ? 12.815  -50.814 98.021  1.00 42.03  ? 40  ARG F CG  1 
ATOM   7007 C  CD  . ARG F 1 40  ? 13.247  -52.092 97.306  1.00 42.36  ? 40  ARG F CD  1 
ATOM   7008 N  NE  . ARG F 1 40  ? 14.430  -52.718 97.900  1.00 51.18  ? 40  ARG F NE  1 
ATOM   7009 C  CZ  . ARG F 1 40  ? 14.809  -53.983 97.692  1.00 51.98  ? 40  ARG F CZ  1 
ATOM   7010 N  NH1 . ARG F 1 40  ? 14.092  -54.785 96.908  1.00 49.89  ? 40  ARG F NH1 1 
ATOM   7011 N  NH2 . ARG F 1 40  ? 15.902  -54.456 98.283  1.00 42.18  ? 40  ARG F NH2 1 
ATOM   7012 N  N   . ASP F 1 41  ? 14.957  -47.899 100.631 1.00 41.62  ? 41  ASP F N   1 
ATOM   7013 C  CA  . ASP F 1 41  ? 16.102  -47.307 101.320 1.00 46.51  ? 41  ASP F CA  1 
ATOM   7014 C  C   . ASP F 1 41  ? 17.443  -47.927 100.909 1.00 46.38  ? 41  ASP F C   1 
ATOM   7015 O  O   . ASP F 1 41  ? 18.484  -47.289 101.094 1.00 43.34  ? 41  ASP F O   1 
ATOM   7016 C  CB  . ASP F 1 41  ? 15.935  -47.419 102.831 1.00 43.36  ? 41  ASP F CB  1 
ATOM   7017 C  CG  . ASP F 1 41  ? 16.263  -48.791 103.343 1.00 46.56  ? 41  ASP F CG  1 
ATOM   7018 O  OD1 . ASP F 1 41  ? 15.379  -49.678 103.295 1.00 47.69  ? 41  ASP F OD1 1 
ATOM   7019 O  OD2 . ASP F 1 41  ? 17.424  -48.986 103.778 1.00 50.79  ? 41  ASP F OD2 1 
ATOM   7020 N  N   . ASP F 1 42  ? 17.460  -49.150 100.377 1.00 41.29  ? 42  ASP F N   1 
ATOM   7021 C  CA  . ASP F 1 42  ? 18.708  -49.723 99.883  1.00 43.97  ? 42  ASP F CA  1 
ATOM   7022 C  C   . ASP F 1 42  ? 18.916  -49.503 98.378  1.00 43.32  ? 42  ASP F C   1 
ATOM   7023 O  O   . ASP F 1 42  ? 19.827  -50.106 97.800  1.00 39.36  ? 42  ASP F O   1 
ATOM   7024 C  CB  . ASP F 1 42  ? 18.789  -51.223 100.209 1.00 33.60  ? 42  ASP F CB  1 
ATOM   7025 C  CG  . ASP F 1 42  ? 17.574  -52.008 99.706  1.00 45.00  ? 42  ASP F CG  1 
ATOM   7026 O  OD1 . ASP F 1 42  ? 16.621  -51.379 99.213  1.00 48.83  ? 42  ASP F OD1 1 
ATOM   7027 O  OD2 . ASP F 1 42  ? 17.563  -53.255 99.805  1.00 46.01  ? 42  ASP F OD2 1 
ATOM   7028 N  N   . VAL F 1 43  ? 18.108  -48.659 97.734  1.00 40.58  ? 43  VAL F N   1 
ATOM   7029 C  CA  . VAL F 1 43  ? 18.281  -48.383 96.308  1.00 41.21  ? 43  VAL F CA  1 
ATOM   7030 C  C   . VAL F 1 43  ? 18.378  -46.878 96.104  1.00 36.84  ? 43  VAL F C   1 
ATOM   7031 O  O   . VAL F 1 43  ? 19.421  -46.376 95.687  1.00 39.58  ? 43  VAL F O   1 
ATOM   7032 C  CB  . VAL F 1 43  ? 17.150  -48.982 95.448  1.00 39.43  ? 43  VAL F CB  1 
ATOM   7033 C  CG1 . VAL F 1 43  ? 17.414  -48.704 93.954  1.00 34.88  ? 43  VAL F CG1 1 
ATOM   7034 C  CG2 . VAL F 1 43  ? 17.015  -50.471 95.692  1.00 31.43  ? 43  VAL F CG2 1 
ATOM   7035 N  N   . CYS F 1 44  ? 17.293  -46.148 96.354  1.00 36.13  ? 44  CYS F N   1 
ATOM   7036 C  CA  . CYS F 1 44  ? 17.350  -44.687 96.502  1.00 41.04  ? 44  CYS F CA  1 
ATOM   7037 C  C   . CYS F 1 44  ? 17.804  -43.996 95.213  1.00 38.93  ? 44  CYS F C   1 
ATOM   7038 O  O   . CYS F 1 44  ? 18.829  -43.318 95.187  1.00 38.02  ? 44  CYS F O   1 
ATOM   7039 C  CB  . CYS F 1 44  ? 18.299  -44.278 97.645  1.00 37.52  ? 44  CYS F CB  1 
ATOM   7040 S  SG  . CYS F 1 44  ? 17.968  -44.803 99.357  1.00 69.33  ? 44  CYS F SG  1 
ATOM   7041 N  N   . LEU F 1 45  ? 17.037  -44.160 94.136  1.00 38.11  ? 45  LEU F N   1 
ATOM   7042 C  CA  . LEU F 1 45  ? 17.363  -43.511 92.867  1.00 40.75  ? 45  LEU F CA  1 
ATOM   7043 C  C   . LEU F 1 45  ? 16.162  -42.649 92.468  1.00 40.19  ? 45  LEU F C   1 
ATOM   7044 O  O   . LEU F 1 45  ? 15.305  -43.088 91.696  1.00 40.03  ? 45  LEU F O   1 
ATOM   7045 C  CB  . LEU F 1 45  ? 17.732  -44.528 91.791  1.00 33.36  ? 45  LEU F CB  1 
ATOM   7046 C  CG  . LEU F 1 45  ? 19.081  -45.208 92.103  1.00 39.78  ? 45  LEU F CG  1 
ATOM   7047 C  CD1 . LEU F 1 45  ? 19.417  -46.383 91.157  1.00 34.11  ? 45  LEU F CD1 1 
ATOM   7048 C  CD2 . LEU F 1 45  ? 20.211  -44.176 92.088  1.00 32.27  ? 45  LEU F CD2 1 
ATOM   7049 N  N   . PRO F 1 46  ? 16.090  -41.414 92.972  1.00 41.09  ? 46  PRO F N   1 
ATOM   7050 C  CA  . PRO F 1 46  ? 14.844  -40.648 92.797  1.00 33.86  ? 46  PRO F CA  1 
ATOM   7051 C  C   . PRO F 1 46  ? 14.603  -40.249 91.363  1.00 36.26  ? 46  PRO F C   1 
ATOM   7052 O  O   . PRO F 1 46  ? 13.441  -40.122 90.960  1.00 39.70  ? 46  PRO F O   1 
ATOM   7053 C  CB  . PRO F 1 46  ? 15.035  -39.421 93.708  1.00 29.03  ? 46  PRO F CB  1 
ATOM   7054 C  CG  . PRO F 1 46  ? 16.463  -39.492 94.249  1.00 33.08  ? 46  PRO F CG  1 
ATOM   7055 C  CD  . PRO F 1 46  ? 17.181  -40.609 93.543  1.00 34.22  ? 46  PRO F CD  1 
ATOM   7056 N  N   . GLY F 1 47  ? 15.653  -40.046 90.579  1.00 36.01  ? 47  GLY F N   1 
ATOM   7057 C  CA  . GLY F 1 47  ? 15.488  -39.885 89.154  1.00 37.39  ? 47  GLY F CA  1 
ATOM   7058 C  C   . GLY F 1 47  ? 14.743  -41.052 88.535  1.00 37.91  ? 47  GLY F C   1 
ATOM   7059 O  O   . GLY F 1 47  ? 13.690  -40.854 87.914  1.00 37.37  ? 47  GLY F O   1 
ATOM   7060 N  N   . PHE F 1 48  ? 15.264  -42.274 88.701  1.00 36.03  ? 48  PHE F N   1 
ATOM   7061 C  CA  . PHE F 1 48  ? 14.550  -43.442 88.196  1.00 34.22  ? 48  PHE F CA  1 
ATOM   7062 C  C   . PHE F 1 48  ? 13.149  -43.509 88.783  1.00 36.80  ? 48  PHE F C   1 
ATOM   7063 O  O   . PHE F 1 48  ? 12.188  -43.856 88.081  1.00 33.40  ? 48  PHE F O   1 
ATOM   7064 C  CB  . PHE F 1 48  ? 15.306  -44.724 88.524  1.00 35.41  ? 48  PHE F CB  1 
ATOM   7065 C  CG  . PHE F 1 48  ? 16.544  -44.954 87.686  1.00 35.33  ? 48  PHE F CG  1 
ATOM   7066 C  CD1 . PHE F 1 48  ? 17.792  -44.512 88.124  1.00 39.06  ? 48  PHE F CD1 1 
ATOM   7067 C  CD2 . PHE F 1 48  ? 16.472  -45.667 86.507  1.00 35.86  ? 48  PHE F CD2 1 
ATOM   7068 C  CE1 . PHE F 1 48  ? 18.945  -44.753 87.372  1.00 41.93  ? 48  PHE F CE1 1 
ATOM   7069 C  CE2 . PHE F 1 48  ? 17.619  -45.912 85.747  1.00 44.84  ? 48  PHE F CE2 1 
ATOM   7070 C  CZ  . PHE F 1 48  ? 18.857  -45.455 86.186  1.00 43.82  ? 48  PHE F CZ  1 
ATOM   7071 N  N   . ALA F 1 49  ? 13.010  -43.142 90.062  1.00 31.21  ? 49  ALA F N   1 
ATOM   7072 C  CA  . ALA F 1 49  ? 11.718  -43.252 90.730  1.00 36.63  ? 49  ALA F CA  1 
ATOM   7073 C  C   . ALA F 1 49  ? 10.691  -42.363 90.054  1.00 35.11  ? 49  ALA F C   1 
ATOM   7074 O  O   . ALA F 1 49  ? 9.620   -42.828 89.645  1.00 38.14  ? 49  ALA F O   1 
ATOM   7075 C  CB  . ALA F 1 49  ? 11.855  -42.898 92.216  1.00 33.05  ? 49  ALA F CB  1 
ATOM   7076 N  N   . LYS F 1 50  ? 11.026  -41.079 89.905  1.00 40.17  ? 50  LYS F N   1 
ATOM   7077 C  CA  . LYS F 1 50  ? 10.176  -40.115 89.209  1.00 40.52  ? 50  LYS F CA  1 
ATOM   7078 C  C   . LYS F 1 50  ? 9.861   -40.567 87.783  1.00 44.84  ? 50  LYS F C   1 
ATOM   7079 O  O   . LYS F 1 50  ? 8.693   -40.585 87.372  1.00 48.63  ? 50  LYS F O   1 
ATOM   7080 C  CB  . LYS F 1 50  ? 10.865  -38.748 89.208  1.00 42.19  ? 50  LYS F CB  1 
ATOM   7081 C  CG  . LYS F 1 50  ? 10.135  -37.637 88.479  1.00 49.42  ? 50  LYS F CG  1 
ATOM   7082 C  CD  . LYS F 1 50  ? 10.655  -36.252 88.913  1.00 58.00  ? 50  LYS F CD  1 
ATOM   7083 C  CE  . LYS F 1 50  ? 10.058  -35.108 88.083  1.00 64.61  ? 50  LYS F CE  1 
ATOM   7084 N  NZ  . LYS F 1 50  ? 10.954  -34.655 86.961  1.00 72.69  ? 50  LYS F NZ  1 
ATOM   7085 N  N   . PHE F 1 51  ? 10.889  -40.948 87.017  1.00 36.18  ? 51  PHE F N   1 
ATOM   7086 C  CA  . PHE F 1 51  ? 10.689  -41.317 85.613  1.00 40.82  ? 51  PHE F CA  1 
ATOM   7087 C  C   . PHE F 1 51  ? 9.664   -42.449 85.459  1.00 40.42  ? 51  PHE F C   1 
ATOM   7088 O  O   . PHE F 1 51  ? 8.737   -42.350 84.642  1.00 34.00  ? 51  PHE F O   1 
ATOM   7089 C  CB  . PHE F 1 51  ? 12.032  -41.705 84.981  1.00 30.03  ? 51  PHE F CB  1 
ATOM   7090 C  CG  . PHE F 1 51  ? 11.919  -42.221 83.573  1.00 38.41  ? 51  PHE F CG  1 
ATOM   7091 C  CD1 . PHE F 1 51  ? 11.783  -41.347 82.506  1.00 36.40  ? 51  PHE F CD1 1 
ATOM   7092 C  CD2 . PHE F 1 51  ? 11.947  -43.592 83.315  1.00 37.63  ? 51  PHE F CD2 1 
ATOM   7093 C  CE1 . PHE F 1 51  ? 11.684  -41.828 81.201  1.00 39.05  ? 51  PHE F CE1 1 
ATOM   7094 C  CE2 . PHE F 1 51  ? 11.855  -44.078 82.023  1.00 36.38  ? 51  PHE F CE2 1 
ATOM   7095 C  CZ  . PHE F 1 51  ? 11.714  -43.187 80.958  1.00 36.80  ? 51  PHE F CZ  1 
ATOM   7096 N  N   . PHE F 1 52  ? 9.817   -43.537 86.233  1.00 38.04  ? 52  PHE F N   1 
ATOM   7097 C  CA  . PHE F 1 52  ? 8.856   -44.644 86.172  1.00 39.54  ? 52  PHE F CA  1 
ATOM   7098 C  C   . PHE F 1 52  ? 7.493   -44.261 86.753  1.00 40.14  ? 52  PHE F C   1 
ATOM   7099 O  O   . PHE F 1 52  ? 6.469   -44.738 86.261  1.00 38.65  ? 52  PHE F O   1 
ATOM   7100 C  CB  . PHE F 1 52  ? 9.404   -45.880 86.893  1.00 34.01  ? 52  PHE F CB  1 
ATOM   7101 C  CG  . PHE F 1 52  ? 10.593  -46.479 86.221  1.00 37.23  ? 52  PHE F CG  1 
ATOM   7102 C  CD1 . PHE F 1 52  ? 10.578  -46.713 84.851  1.00 33.39  ? 52  PHE F CD1 1 
ATOM   7103 C  CD2 . PHE F 1 52  ? 11.739  -46.788 86.950  1.00 35.48  ? 52  PHE F CD2 1 
ATOM   7104 C  CE1 . PHE F 1 52  ? 11.682  -47.244 84.210  1.00 37.68  ? 52  PHE F CE1 1 
ATOM   7105 C  CE2 . PHE F 1 52  ? 12.848  -47.317 86.322  1.00 34.51  ? 52  PHE F CE2 1 
ATOM   7106 C  CZ  . PHE F 1 52  ? 12.822  -47.546 84.942  1.00 40.15  ? 52  PHE F CZ  1 
ATOM   7107 N  N   . LYS F 1 53  ? 7.448   -43.413 87.786  1.00 36.30  ? 53  LYS F N   1 
ATOM   7108 C  CA  . LYS F 1 53  ? 6.153   -42.943 88.270  1.00 43.83  ? 53  LYS F CA  1 
ATOM   7109 C  C   . LYS F 1 53  ? 5.384   -42.230 87.160  1.00 42.10  ? 53  LYS F C   1 
ATOM   7110 O  O   . LYS F 1 53  ? 4.181   -42.463 86.976  1.00 43.89  ? 53  LYS F O   1 
ATOM   7111 C  CB  . LYS F 1 53  ? 6.324   -42.027 89.488  1.00 39.85  ? 53  LYS F CB  1 
ATOM   7112 C  CG  . LYS F 1 53  ? 5.235   -42.193 90.535  1.00 50.98  ? 53  LYS F CG  1 
ATOM   7113 C  CD  . LYS F 1 53  ? 4.056   -41.246 90.262  1.00 60.27  ? 53  LYS F CD  1 
ATOM   7114 C  CE  . LYS F 1 53  ? 2.768   -41.709 90.943  1.00 51.34  ? 53  LYS F CE  1 
ATOM   7115 N  NZ  . LYS F 1 53  ? 1.526   -41.185 90.276  1.00 60.89  ? 53  LYS F NZ  1 
ATOM   7116 N  N   . GLU F 1 54  ? 6.069   -41.392 86.381  1.00 41.23  ? 54  GLU F N   1 
ATOM   7117 C  CA  . GLU F 1 54  ? 5.418   -40.675 85.287  1.00 47.31  ? 54  GLU F CA  1 
ATOM   7118 C  C   . GLU F 1 54  ? 5.078   -41.585 84.106  1.00 46.95  ? 54  GLU F C   1 
ATOM   7119 O  O   . GLU F 1 54  ? 4.034   -41.394 83.468  1.00 51.23  ? 54  GLU F O   1 
ATOM   7120 C  CB  . GLU F 1 54  ? 6.299   -39.506 84.837  1.00 43.91  ? 54  GLU F CB  1 
ATOM   7121 C  CG  . GLU F 1 54  ? 6.450   -38.453 85.932  1.00 50.96  ? 54  GLU F CG  1 
ATOM   7122 C  CD  . GLU F 1 54  ? 7.396   -37.313 85.553  1.00 61.37  ? 54  GLU F CD  1 
ATOM   7123 O  OE1 . GLU F 1 54  ? 8.102   -37.420 84.521  1.00 58.02  ? 54  GLU F OE1 1 
ATOM   7124 O  OE2 . GLU F 1 54  ? 7.436   -36.314 86.306  1.00 62.20  ? 54  GLU F OE2 1 
ATOM   7125 N  N   . SER F 1 55  ? 5.921   -42.576 83.801  1.00 37.44  ? 55  SER F N   1 
ATOM   7126 C  CA  . SER F 1 55  ? 5.516   -43.582 82.829  1.00 38.00  ? 55  SER F CA  1 
ATOM   7127 C  C   . SER F 1 55  ? 4.328   -44.402 83.322  1.00 40.55  ? 55  SER F C   1 
ATOM   7128 O  O   . SER F 1 55  ? 3.470   -44.788 82.519  1.00 40.06  ? 55  SER F O   1 
ATOM   7129 C  CB  . SER F 1 55  ? 6.686   -44.506 82.472  1.00 34.14  ? 55  SER F CB  1 
ATOM   7130 O  OG  . SER F 1 55  ? 7.895   -43.792 82.299  1.00 41.94  ? 55  SER F OG  1 
ATOM   7131 N  N   . SER F 1 56  ? 4.239   -44.682 84.620  1.00 35.55  ? 56  SER F N   1 
ATOM   7132 C  CA  . SER F 1 56  ? 3.108   -45.483 85.065  1.00 44.45  ? 56  SER F CA  1 
ATOM   7133 C  C   . SER F 1 56  ? 1.805   -44.719 84.843  1.00 41.72  ? 56  SER F C   1 
ATOM   7134 O  O   . SER F 1 56  ? 0.827   -45.289 84.342  1.00 38.32  ? 56  SER F O   1 
ATOM   7135 C  CB  . SER F 1 56  ? 3.268   -45.907 86.527  1.00 35.83  ? 56  SER F CB  1 
ATOM   7136 O  OG  . SER F 1 56  ? 2.017   -46.302 87.070  1.00 34.92  ? 56  SER F OG  1 
ATOM   7137 N  N   . ASP F 1 57  ? 1.802   -43.405 85.142  1.00 41.75  ? 57  ASP F N   1 
ATOM   7138 C  CA  . ASP F 1 57  ? 0.606   -42.580 84.924  1.00 44.52  ? 57  ASP F CA  1 
ATOM   7139 C  C   . ASP F 1 57  ? 0.273   -42.450 83.443  1.00 44.12  ? 57  ASP F C   1 
ATOM   7140 O  O   . ASP F 1 57  ? -0.901  -42.495 83.066  1.00 41.05  ? 57  ASP F O   1 
ATOM   7141 C  CB  . ASP F 1 57  ? 0.777   -41.192 85.533  1.00 37.74  ? 57  ASP F CB  1 
ATOM   7142 C  CG  . ASP F 1 57  ? 0.872   -41.228 87.040  1.00 51.90  ? 57  ASP F CG  1 
ATOM   7143 O  OD1 . ASP F 1 57  ? 0.437   -42.243 87.637  1.00 53.80  ? 57  ASP F OD1 1 
ATOM   7144 O  OD2 . ASP F 1 57  ? 1.389   -40.244 87.628  1.00 52.09  ? 57  ASP F OD2 1 
ATOM   7145 N  N   . GLU F 1 58  ? 1.288   -42.308 82.583  1.00 41.85  ? 58  GLU F N   1 
ATOM   7146 C  CA  . GLU F 1 58  ? 1.017   -42.230 81.150  1.00 50.26  ? 58  GLU F CA  1 
ATOM   7147 C  C   . GLU F 1 58  ? 0.400   -43.521 80.618  1.00 50.27  ? 58  GLU F C   1 
ATOM   7148 O  O   . GLU F 1 58  ? -0.509  -43.483 79.782  1.00 45.51  ? 58  GLU F O   1 
ATOM   7149 C  CB  . GLU F 1 58  ? 2.289   -41.887 80.378  1.00 47.00  ? 58  GLU F CB  1 
ATOM   7150 C  CG  . GLU F 1 58  ? 2.721   -40.453 80.585  1.00 61.56  ? 58  GLU F CG  1 
ATOM   7151 C  CD  . GLU F 1 58  ? 4.198   -40.221 80.313  1.00 81.39  ? 58  GLU F CD  1 
ATOM   7152 O  OE1 . GLU F 1 58  ? 4.790   -39.346 80.989  1.00 79.07  ? 58  GLU F OE1 1 
ATOM   7153 O  OE2 . GLU F 1 58  ? 4.756   -40.888 79.406  1.00 80.36  ? 58  GLU F OE2 1 
ATOM   7154 N  N   . GLU F 1 59  ? 0.881   -44.675 81.079  1.00 45.59  ? 59  GLU F N   1 
ATOM   7155 C  CA  . GLU F 1 59  ? 0.288   -45.931 80.632  1.00 47.31  ? 59  GLU F CA  1 
ATOM   7156 C  C   . GLU F 1 59  ? -1.178  -46.027 81.052  1.00 44.74  ? 59  GLU F C   1 
ATOM   7157 O  O   . GLU F 1 59  ? -2.042  -46.392 80.247  1.00 42.23  ? 59  GLU F O   1 
ATOM   7158 C  CB  . GLU F 1 59  ? 1.090   -47.115 81.168  1.00 42.98  ? 59  GLU F CB  1 
ATOM   7159 C  CG  . GLU F 1 59  ? 2.385   -47.329 80.439  1.00 44.41  ? 59  GLU F CG  1 
ATOM   7160 C  CD  . GLU F 1 59  ? 2.187   -47.319 78.933  1.00 58.15  ? 59  GLU F CD  1 
ATOM   7161 O  OE1 . GLU F 1 59  ? 1.200   -47.925 78.457  1.00 59.98  ? 59  GLU F OE1 1 
ATOM   7162 O  OE2 . GLU F 1 59  ? 3.010   -46.704 78.227  1.00 58.13  ? 59  GLU F OE2 1 
ATOM   7163 N  N   . ARG F 1 60  ? -1.478  -45.670 82.301  1.00 36.39  ? 60  ARG F N   1 
ATOM   7164 C  CA  . ARG F 1 60  ? -2.866  -45.679 82.754  1.00 44.93  ? 60  ARG F CA  1 
ATOM   7165 C  C   . ARG F 1 60  ? -3.750  -44.794 81.879  1.00 47.53  ? 60  ARG F C   1 
ATOM   7166 O  O   . ARG F 1 60  ? -4.865  -45.189 81.512  1.00 43.45  ? 60  ARG F O   1 
ATOM   7167 C  CB  . ARG F 1 60  ? -2.944  -45.231 84.207  1.00 36.62  ? 60  ARG F CB  1 
ATOM   7168 C  CG  . ARG F 1 60  ? -4.309  -45.394 84.840  1.00 42.63  ? 60  ARG F CG  1 
ATOM   7169 C  CD  . ARG F 1 60  ? -4.178  -45.219 86.352  1.00 49.88  ? 60  ARG F CD  1 
ATOM   7170 N  NE  . ARG F 1 60  ? -5.449  -45.333 87.067  1.00 47.90  ? 60  ARG F NE  1 
ATOM   7171 C  CZ  . ARG F 1 60  ? -6.152  -44.301 87.528  1.00 52.33  ? 60  ARG F CZ  1 
ATOM   7172 N  NH1 . ARG F 1 60  ? -7.305  -44.504 88.175  1.00 42.28  ? 60  ARG F NH1 1 
ATOM   7173 N  NH2 . ARG F 1 60  ? -5.703  -43.064 87.339  1.00 55.17  ? 60  ARG F NH2 1 
ATOM   7174 N  N   . GLU F 1 61  ? -3.269  -43.598 81.527  1.00 44.63  ? 61  GLU F N   1 
ATOM   7175 C  CA  . GLU F 1 61  ? -4.039  -42.738 80.640  1.00 47.94  ? 61  GLU F CA  1 
ATOM   7176 C  C   . GLU F 1 61  ? -4.205  -43.373 79.260  1.00 51.66  ? 61  GLU F C   1 
ATOM   7177 O  O   . GLU F 1 61  ? -5.290  -43.297 78.670  1.00 45.06  ? 61  GLU F O   1 
ATOM   7178 C  CB  . GLU F 1 61  ? -3.385  -41.362 80.533  1.00 50.43  ? 61  GLU F CB  1 
ATOM   7179 C  CG  . GLU F 1 61  ? -3.431  -40.536 81.828  1.00 59.70  ? 61  GLU F CG  1 
ATOM   7180 C  CD  . GLU F 1 61  ? -4.850  -40.232 82.316  1.00 73.71  ? 61  GLU F CD  1 
ATOM   7181 O  OE1 . GLU F 1 61  ? -5.201  -40.669 83.447  1.00 65.43  ? 61  GLU F OE1 1 
ATOM   7182 O  OE2 . GLU F 1 61  ? -5.606  -39.556 81.569  1.00 69.64  ? 61  GLU F OE2 1 
ATOM   7183 N  N   . HIS F 1 62  ? -3.160  -44.035 78.741  1.00 51.30  ? 62  HIS F N   1 
ATOM   7184 C  CA  . HIS F 1 62  ? -3.304  -44.711 77.452  1.00 50.92  ? 62  HIS F CA  1 
ATOM   7185 C  C   . HIS F 1 62  ? -4.387  -45.789 77.509  1.00 50.54  ? 62  HIS F C   1 
ATOM   7186 O  O   . HIS F 1 62  ? -5.191  -45.918 76.576  1.00 53.26  ? 62  HIS F O   1 
ATOM   7187 C  CB  . HIS F 1 62  ? -1.971  -45.307 76.995  1.00 50.55  ? 62  HIS F CB  1 
ATOM   7188 C  CG  . HIS F 1 62  ? -0.915  -44.283 76.695  1.00 66.47  ? 62  HIS F CG  1 
ATOM   7189 N  ND1 . HIS F 1 62  ? 0.313   -44.613 76.158  1.00 69.62  ? 62  HIS F ND1 1 
ATOM   7190 C  CD2 . HIS F 1 62  ? -0.894  -42.938 76.875  1.00 66.82  ? 62  HIS F CD2 1 
ATOM   7191 C  CE1 . HIS F 1 62  ? 1.043   -43.520 76.020  1.00 63.69  ? 62  HIS F CE1 1 
ATOM   7192 N  NE2 . HIS F 1 62  ? 0.334   -42.489 76.449  1.00 63.07  ? 62  HIS F NE2 1 
ATOM   7193 N  N   . ALA F 1 63  ? -4.447  -46.557 78.603  1.00 41.34  ? 63  ALA F N   1 
ATOM   7194 C  CA  . ALA F 1 63  ? -5.526  -47.529 78.761  1.00 43.59  ? 63  ALA F CA  1 
ATOM   7195 C  C   . ALA F 1 63  ? -6.886  -46.842 78.702  1.00 49.14  ? 63  ALA F C   1 
ATOM   7196 O  O   . ALA F 1 63  ? -7.802  -47.300 78.012  1.00 44.45  ? 63  ALA F O   1 
ATOM   7197 C  CB  . ALA F 1 63  ? -5.364  -48.298 80.077  1.00 40.12  ? 63  ALA F CB  1 
ATOM   7198 N  N   . GLN F 1 64  ? -7.021  -45.715 79.401  1.00 44.91  ? 64  GLN F N   1 
ATOM   7199 C  CA  . GLN F 1 64  ? -8.260  -44.958 79.362  1.00 44.32  ? 64  GLN F CA  1 
ATOM   7200 C  C   . GLN F 1 64  ? -8.578  -44.431 77.964  1.00 47.30  ? 64  GLN F C   1 
ATOM   7201 O  O   . GLN F 1 64  ? -9.746  -44.209 77.642  1.00 45.67  ? 64  GLN F O   1 
ATOM   7202 C  CB  . GLN F 1 64  ? -8.182  -43.825 80.378  1.00 43.65  ? 64  GLN F CB  1 
ATOM   7203 C  CG  . GLN F 1 64  ? -8.206  -44.356 81.791  1.00 41.38  ? 64  GLN F CG  1 
ATOM   7204 C  CD  . GLN F 1 64  ? -8.368  -43.282 82.833  1.00 49.20  ? 64  GLN F CD  1 
ATOM   7205 O  OE1 . GLN F 1 64  ? -9.429  -42.652 82.963  1.00 46.11  ? 64  GLN F OE1 1 
ATOM   7206 N  NE2 . GLN F 1 64  ? -7.311  -43.066 83.597  1.00 49.26  ? 64  GLN F NE2 1 
ATOM   7207 N  N   . THR F 1 65  ? -7.571  -44.247 77.110  1.00 51.32  ? 65  THR F N   1 
ATOM   7208 C  CA  . THR F 1 65  ? -7.856  -43.835 75.737  1.00 48.47  ? 65  THR F CA  1 
ATOM   7209 C  C   . THR F 1 65  ? -8.527  -44.955 74.957  1.00 45.08  ? 65  THR F C   1 
ATOM   7210 O  O   . THR F 1 65  ? -9.491  -44.716 74.223  1.00 48.53  ? 65  THR F O   1 
ATOM   7211 C  CB  . THR F 1 65  ? -6.574  -43.392 75.036  1.00 48.32  ? 65  THR F CB  1 
ATOM   7212 O  OG1 . THR F 1 65  ? -6.218  -42.085 75.485  1.00 47.69  ? 65  THR F OG1 1 
ATOM   7213 C  CG2 . THR F 1 65  ? -6.756  -43.366 73.525  1.00 49.41  ? 65  THR F CG2 1 
ATOM   7214 N  N   . PHE F 1 66  ? -8.040  -46.182 75.097  1.00 44.54  ? 66  PHE F N   1 
ATOM   7215 C  CA  . PHE F 1 66  ? -8.712  -47.286 74.431  1.00 47.66  ? 66  PHE F CA  1 
ATOM   7216 C  C   . PHE F 1 66  ? -10.070 -47.571 75.050  1.00 53.23  ? 66  PHE F C   1 
ATOM   7217 O  O   . PHE F 1 66  ? -10.937 -48.131 74.373  1.00 55.50  ? 66  PHE F O   1 
ATOM   7218 C  CB  . PHE F 1 66  ? -7.837  -48.540 74.457  1.00 45.96  ? 66  PHE F CB  1 
ATOM   7219 C  CG  . PHE F 1 66  ? -6.590  -48.407 73.649  1.00 56.20  ? 66  PHE F CG  1 
ATOM   7220 C  CD1 . PHE F 1 66  ? -6.660  -48.240 72.274  1.00 57.44  ? 66  PHE F CD1 1 
ATOM   7221 C  CD2 . PHE F 1 66  ? -5.346  -48.435 74.255  1.00 53.56  ? 66  PHE F CD2 1 
ATOM   7222 C  CE1 . PHE F 1 66  ? -5.517  -48.092 71.522  1.00 62.34  ? 66  PHE F CE1 1 
ATOM   7223 C  CE2 . PHE F 1 66  ? -4.196  -48.292 73.497  1.00 63.24  ? 66  PHE F CE2 1 
ATOM   7224 C  CZ  . PHE F 1 66  ? -4.286  -48.118 72.130  1.00 60.69  ? 66  PHE F CZ  1 
ATOM   7225 N  N   . MET F 1 67  ? -10.277 -47.193 76.317  1.00 51.02  ? 67  MET F N   1 
ATOM   7226 C  CA  . MET F 1 67  ? -11.574 -47.414 76.945  1.00 47.99  ? 67  MET F CA  1 
ATOM   7227 C  C   . MET F 1 67  ? -12.615 -46.456 76.387  1.00 46.64  ? 67  MET F C   1 
ATOM   7228 O  O   . MET F 1 67  ? -13.731 -46.869 76.058  1.00 46.96  ? 67  MET F O   1 
ATOM   7229 C  CB  . MET F 1 67  ? -11.461 -47.273 78.456  1.00 44.93  ? 67  MET F CB  1 
ATOM   7230 C  CG  . MET F 1 67  ? -10.538 -48.314 79.086  1.00 52.77  ? 67  MET F CG  1 
ATOM   7231 S  SD  . MET F 1 67  ? -10.425 -48.104 80.878  1.00 42.00  ? 67  MET F SD  1 
ATOM   7232 C  CE  . MET F 1 67  ? -11.886 -49.027 81.389  1.00 49.12  ? 67  MET F CE  1 
ATOM   7233 N  N   . LYS F 1 68  ? -12.266 -45.170 76.270  1.00 48.95  ? 68  LYS F N   1 
ATOM   7234 C  CA  . LYS F 1 68  ? -13.171 -44.214 75.638  1.00 49.96  ? 68  LYS F CA  1 
ATOM   7235 C  C   . LYS F 1 68  ? -13.450 -44.591 74.190  1.00 53.26  ? 68  LYS F C   1 
ATOM   7236 O  O   . LYS F 1 68  ? -14.582 -44.446 73.720  1.00 53.21  ? 68  LYS F O   1 
ATOM   7237 C  CB  . LYS F 1 68  ? -12.616 -42.786 75.732  1.00 46.25  ? 68  LYS F CB  1 
ATOM   7238 C  CG  . LYS F 1 68  ? -12.149 -42.438 77.130  1.00 57.50  ? 68  LYS F CG  1 
ATOM   7239 C  CD  . LYS F 1 68  ? -11.974 -40.956 77.391  1.00 60.87  ? 68  LYS F CD  1 
ATOM   7240 C  CE  . LYS F 1 68  ? -12.457 -40.618 78.820  1.00 64.89  ? 68  LYS F CE  1 
ATOM   7241 N  NZ  . LYS F 1 68  ? -13.864 -40.078 78.892  1.00 66.95  ? 68  LYS F NZ  1 
ATOM   7242 N  N   . TYR F 1 69  ? -12.444 -45.109 73.471  1.00 58.33  ? 69  TYR F N   1 
ATOM   7243 C  CA  . TYR F 1 69  ? -12.678 -45.491 72.081  1.00 57.26  ? 69  TYR F CA  1 
ATOM   7244 C  C   . TYR F 1 69  ? -13.596 -46.705 71.986  1.00 53.70  ? 69  TYR F C   1 
ATOM   7245 O  O   . TYR F 1 69  ? -14.483 -46.750 71.127  1.00 58.83  ? 69  TYR F O   1 
ATOM   7246 C  CB  . TYR F 1 69  ? -11.359 -45.753 71.352  1.00 53.75  ? 69  TYR F CB  1 
ATOM   7247 C  CG  . TYR F 1 69  ? -11.593 -46.115 69.905  1.00 55.19  ? 69  TYR F CG  1 
ATOM   7248 C  CD1 . TYR F 1 69  ? -11.894 -45.136 68.962  1.00 61.12  ? 69  TYR F CD1 1 
ATOM   7249 C  CD2 . TYR F 1 69  ? -11.563 -47.436 69.490  1.00 59.96  ? 69  TYR F CD2 1 
ATOM   7250 C  CE1 . TYR F 1 69  ? -12.141 -45.459 67.640  1.00 60.38  ? 69  TYR F CE1 1 
ATOM   7251 C  CE2 . TYR F 1 69  ? -11.813 -47.775 68.172  1.00 64.93  ? 69  TYR F CE2 1 
ATOM   7252 C  CZ  . TYR F 1 69  ? -12.091 -46.782 67.249  1.00 68.61  ? 69  TYR F CZ  1 
ATOM   7253 O  OH  . TYR F 1 69  ? -12.337 -47.131 65.936  1.00 74.53  ? 69  TYR F OH  1 
ATOM   7254 N  N   . GLN F 1 70  ? -13.394 -47.704 72.846  1.00 53.21  ? 70  GLN F N   1 
ATOM   7255 C  CA  . GLN F 1 70  ? -14.323 -48.831 72.897  1.00 55.45  ? 70  GLN F CA  1 
ATOM   7256 C  C   . GLN F 1 70  ? -15.762 -48.351 73.072  1.00 55.63  ? 70  GLN F C   1 
ATOM   7257 O  O   . GLN F 1 70  ? -16.645 -48.722 72.294  1.00 53.09  ? 70  GLN F O   1 
ATOM   7258 C  CB  . GLN F 1 70  ? -13.932 -49.783 74.020  1.00 52.63  ? 70  GLN F CB  1 
ATOM   7259 C  CG  . GLN F 1 70  ? -14.806 -51.025 74.114  1.00 55.54  ? 70  GLN F CG  1 
ATOM   7260 C  CD  . GLN F 1 70  ? -14.306 -52.136 73.210  1.00 59.56  ? 70  GLN F CD  1 
ATOM   7261 O  OE1 . GLN F 1 70  ? -14.446 -52.064 71.991  1.00 55.19  ? 70  GLN F OE1 1 
ATOM   7262 N  NE2 . GLN F 1 70  ? -13.716 -53.174 73.808  1.00 57.50  ? 70  GLN F NE2 1 
ATOM   7263 N  N   . ASN F 1 71  ? -15.999 -47.494 74.076  1.00 52.66  ? 71  ASN F N   1 
ATOM   7264 C  CA  . ASN F 1 71  ? -17.317 -46.928 74.316  1.00 50.59  ? 71  ASN F CA  1 
ATOM   7265 C  C   . ASN F 1 71  ? -17.793 -46.110 73.123  1.00 60.55  ? 71  ASN F C   1 
ATOM   7266 O  O   . ASN F 1 71  ? -18.977 -46.096 72.805  1.00 58.84  ? 71  ASN F O   1 
ATOM   7267 C  CB  . ASN F 1 71  ? -17.285 -46.059 75.562  1.00 41.11  ? 71  ASN F CB  1 
ATOM   7268 C  CG  . ASN F 1 71  ? -17.651 -46.847 76.808  1.00 46.02  ? 71  ASN F CG  1 
ATOM   7269 O  OD1 . ASN F 1 71  ? -18.162 -47.975 76.719  1.00 44.20  ? 71  ASN F OD1 1 
ATOM   7270 N  ND2 . ASN F 1 71  ? -17.390 -46.274 77.968  1.00 45.85  ? 71  ASN F ND2 1 
ATOM   7271 N  N   . CYS F 1 72  ? -16.891 -45.401 72.457  1.00 61.09  ? 72  CYS F N   1 
ATOM   7272 C  CA  . CYS F 1 72  ? -17.240 -44.746 71.192  1.00 64.30  ? 72  CYS F CA  1 
ATOM   7273 C  C   . CYS F 1 72  ? -17.742 -45.761 70.166  1.00 65.02  ? 72  CYS F C   1 
ATOM   7274 O  O   . CYS F 1 72  ? -18.932 -45.866 69.926  1.00 73.92  ? 72  CYS F O   1 
ATOM   7275 C  CB  . CYS F 1 72  ? -16.060 -43.956 70.608  1.00 70.38  ? 72  CYS F CB  1 
ATOM   7276 S  SG  . CYS F 1 72  ? -16.338 -43.562 68.898  1.00 92.49  ? 72  CYS F SG  1 
ATOM   7277 N  N   . ARG F 1 73  ? -16.920 -46.545 69.652  1.00 65.36  ? 73  ARG F N   1 
ATOM   7278 C  CA  . ARG F 1 73  ? -17.494 -47.371 68.580  1.00 68.90  ? 73  ARG F CA  1 
ATOM   7279 C  C   . ARG F 1 73  ? -18.638 -48.383 69.019  1.00 63.46  ? 73  ARG F C   1 
ATOM   7280 O  O   . ARG F 1 73  ? -19.036 -49.300 68.262  1.00 70.31  ? 73  ARG F O   1 
ATOM   7281 C  CB  . ARG F 1 73  ? -16.344 -48.114 67.931  1.00 70.73  ? 73  ARG F CB  1 
ATOM   7282 C  CG  . ARG F 1 73  ? -15.296 -47.162 67.331  1.00 71.09  ? 73  ARG F CG  1 
ATOM   7283 C  CD  . ARG F 1 73  ? -15.842 -46.132 66.311  1.00 71.04  ? 73  ARG F CD  1 
ATOM   7284 N  NE  . ARG F 1 73  ? -16.520 -46.745 65.165  1.00 84.11  ? 73  ARG F NE  1 
ATOM   7285 C  CZ  . ARG F 1 73  ? -15.889 -47.417 64.208  1.00 82.65  ? 73  ARG F CZ  1 
ATOM   7286 N  NH1 . ARG F 1 73  ? -14.568 -47.551 64.263  1.00 81.93  ? 73  ARG F NH1 1 
ATOM   7287 N  NH2 . ARG F 1 73  ? -16.568 -47.949 63.202  1.00 81.38  ? 73  ARG F NH2 1 
ATOM   7288 N  N   . GLY F 1 74  ? -19.190 -48.213 70.217  1.00 62.76  ? 74  GLY F N   1 
ATOM   7289 C  CA  . GLY F 1 74  ? -20.324 -48.981 70.664  1.00 55.79  ? 74  GLY F CA  1 
ATOM   7290 C  C   . GLY F 1 74  ? -19.975 -50.324 71.239  1.00 58.19  ? 74  GLY F C   1 
ATOM   7291 O  O   . GLY F 1 74  ? -20.883 -51.126 71.490  1.00 53.93  ? 74  GLY F O   1 
ATOM   7292 N  N   . GLY F 1 75  ? -18.688 -50.598 71.439  1.00 57.46  ? 75  GLY F N   1 
ATOM   7293 C  CA  . GLY F 1 75  ? -18.257 -51.849 72.003  1.00 53.90  ? 75  GLY F CA  1 
ATOM   7294 C  C   . GLY F 1 75  ? -18.440 -51.862 73.495  1.00 54.55  ? 75  GLY F C   1 
ATOM   7295 O  O   . GLY F 1 75  ? -18.876 -50.892 74.117  1.00 59.20  ? 75  GLY F O   1 
ATOM   7296 N  N   . ARG F 1 76  ? -18.087 -52.995 74.077  1.00 47.93  ? 76  ARG F N   1 
ATOM   7297 C  CA  . ARG F 1 76  ? -18.292 -53.247 75.491  1.00 56.22  ? 76  ARG F CA  1 
ATOM   7298 C  C   . ARG F 1 76  ? -16.942 -53.556 76.129  1.00 51.20  ? 76  ARG F C   1 
ATOM   7299 O  O   . ARG F 1 76  ? -16.335 -54.593 75.842  1.00 47.46  ? 76  ARG F O   1 
ATOM   7300 C  CB  . ARG F 1 76  ? -19.309 -54.372 75.690  1.00 53.78  ? 76  ARG F CB  1 
ATOM   7301 C  CG  . ARG F 1 76  ? -20.748 -53.909 75.341  1.00 66.17  ? 76  ARG F CG  1 
ATOM   7302 C  CD  . ARG F 1 76  ? -21.156 -52.621 76.113  1.00 68.31  ? 76  ARG F CD  1 
ATOM   7303 N  NE  . ARG F 1 76  ? -22.454 -52.061 75.707  1.00 65.74  ? 76  ARG F NE  1 
ATOM   7304 C  CZ  . ARG F 1 76  ? -22.630 -50.853 75.164  1.00 68.75  ? 76  ARG F CZ  1 
ATOM   7305 N  NH1 . ARG F 1 76  ? -21.587 -50.042 74.958  1.00 64.84  ? 76  ARG F NH1 1 
ATOM   7306 N  NH2 . ARG F 1 76  ? -23.854 -50.450 74.826  1.00 61.10  ? 76  ARG F NH2 1 
ATOM   7307 N  N   . ILE F 1 77  ? -16.478 -52.625 76.973  1.00 52.43  ? 77  ILE F N   1 
ATOM   7308 C  CA  . ILE F 1 77  ? -15.260 -52.802 77.751  1.00 47.44  ? 77  ILE F CA  1 
ATOM   7309 C  C   . ILE F 1 77  ? -15.396 -54.029 78.628  1.00 48.32  ? 77  ILE F C   1 
ATOM   7310 O  O   . ILE F 1 77  ? -16.337 -54.143 79.423  1.00 41.27  ? 77  ILE F O   1 
ATOM   7311 C  CB  . ILE F 1 77  ? -14.987 -51.566 78.622  1.00 42.17  ? 77  ILE F CB  1 
ATOM   7312 C  CG1 . ILE F 1 77  ? -14.829 -50.309 77.768  1.00 45.42  ? 77  ILE F CG1 1 
ATOM   7313 C  CG2 . ILE F 1 77  ? -13.757 -51.794 79.487  1.00 41.85  ? 77  ILE F CG2 1 
ATOM   7314 C  CD1 . ILE F 1 77  ? -15.093 -49.024 78.525  1.00 41.88  ? 77  ILE F CD1 1 
ATOM   7315 N  N   . VAL F 1 78  ? -14.433 -54.937 78.517  1.00 51.98  ? 78  VAL F N   1 
ATOM   7316 C  CA  . VAL F 1 78  ? -14.355 -56.117 79.368  1.00 48.69  ? 78  VAL F CA  1 
ATOM   7317 C  C   . VAL F 1 78  ? -12.998 -56.087 80.056  1.00 48.67  ? 78  VAL F C   1 
ATOM   7318 O  O   . VAL F 1 78  ? -11.960 -56.235 79.394  1.00 53.44  ? 78  VAL F O   1 
ATOM   7319 C  CB  . VAL F 1 78  ? -14.544 -57.418 78.575  1.00 46.61  ? 78  VAL F CB  1 
ATOM   7320 C  CG1 . VAL F 1 78  ? -14.328 -58.594 79.477  1.00 39.60  ? 78  VAL F CG1 1 
ATOM   7321 C  CG2 . VAL F 1 78  ? -15.937 -57.463 77.961  1.00 39.30  ? 78  VAL F CG2 1 
ATOM   7322 N  N   . LEU F 1 79  ? -13.004 -55.905 81.380  1.00 43.12  ? 79  LEU F N   1 
ATOM   7323 C  CA  . LEU F 1 79  ? -11.789 -55.688 82.161  1.00 50.13  ? 79  LEU F CA  1 
ATOM   7324 C  C   . LEU F 1 79  ? -11.321 -57.016 82.741  1.00 45.16  ? 79  LEU F C   1 
ATOM   7325 O  O   . LEU F 1 79  ? -12.108 -57.738 83.336  1.00 41.42  ? 79  LEU F O   1 
ATOM   7326 C  CB  . LEU F 1 79  ? -12.047 -54.661 83.262  1.00 37.99  ? 79  LEU F CB  1 
ATOM   7327 C  CG  . LEU F 1 79  ? -12.419 -53.273 82.729  1.00 40.62  ? 79  LEU F CG  1 
ATOM   7328 C  CD1 . LEU F 1 79  ? -12.774 -52.336 83.849  1.00 33.51  ? 79  LEU F CD1 1 
ATOM   7329 C  CD2 . LEU F 1 79  ? -11.285 -52.692 81.896  1.00 33.46  ? 79  LEU F CD2 1 
ATOM   7330 N  N   . GLN F 1 80  ? -10.055 -57.352 82.570  1.00 47.04  ? 80  GLN F N   1 
ATOM   7331 C  CA  . GLN F 1 80  ? -9.593  -58.614 83.120  1.00 43.99  ? 80  GLN F CA  1 
ATOM   7332 C  C   . GLN F 1 80  ? -8.710  -58.359 84.336  1.00 42.24  ? 80  GLN F C   1 
ATOM   7333 O  O   . GLN F 1 80  ? -8.391  -57.216 84.683  1.00 37.76  ? 80  GLN F O   1 
ATOM   7334 C  CB  . GLN F 1 80  ? -8.850  -59.430 82.063  1.00 46.43  ? 80  GLN F CB  1 
ATOM   7335 C  CG  . GLN F 1 80  ? -9.748  -60.011 80.971  1.00 53.33  ? 80  GLN F CG  1 
ATOM   7336 C  CD  . GLN F 1 80  ? -9.702  -59.199 79.678  1.00 62.57  ? 80  GLN F CD  1 
ATOM   7337 O  OE1 . GLN F 1 80  ? -8.647  -58.665 79.295  1.00 60.24  ? 80  GLN F OE1 1 
ATOM   7338 N  NE2 . GLN F 1 80  ? -10.845 -59.106 78.992  1.00 59.61  ? 80  GLN F NE2 1 
ATOM   7339 N  N   . GLN F 1 81  ? -8.347  -59.448 85.012  1.00 39.31  ? 81  GLN F N   1 
ATOM   7340 C  CA  . GLN F 1 81  ? -7.290  -59.411 86.011  1.00 38.10  ? 81  GLN F CA  1 
ATOM   7341 C  C   . GLN F 1 81  ? -6.058  -58.703 85.440  1.00 37.43  ? 81  GLN F C   1 
ATOM   7342 O  O   . GLN F 1 81  ? -5.718  -58.857 84.261  1.00 32.79  ? 81  GLN F O   1 
ATOM   7343 C  CB  . GLN F 1 81  ? -6.958  -60.848 86.452  1.00 35.57  ? 81  GLN F CB  1 
ATOM   7344 C  CG  . GLN F 1 81  ? -5.557  -61.081 87.050  1.00 44.80  ? 81  GLN F CG  1 
ATOM   7345 C  CD  . GLN F 1 81  ? -5.501  -62.240 88.082  1.00 53.44  ? 81  GLN F CD  1 
ATOM   7346 O  OE1 . GLN F 1 81  ? -6.371  -62.373 88.950  1.00 54.32  ? 81  GLN F OE1 1 
ATOM   7347 N  NE2 . GLN F 1 81  ? -4.460  -63.071 87.983  1.00 51.72  ? 81  GLN F NE2 1 
ATOM   7348 N  N   . ILE F 1 82  ? -5.420  -57.872 86.257  1.00 35.98  ? 82  ILE F N   1 
ATOM   7349 C  CA  . ILE F 1 82  ? -4.160  -57.242 85.874  1.00 34.01  ? 82  ILE F CA  1 
ATOM   7350 C  C   . ILE F 1 82  ? -3.063  -58.069 86.518  1.00 36.67  ? 82  ILE F C   1 
ATOM   7351 O  O   . ILE F 1 82  ? -2.978  -58.152 87.755  1.00 36.69  ? 82  ILE F O   1 
ATOM   7352 C  CB  . ILE F 1 82  ? -4.079  -55.773 86.306  1.00 36.90  ? 82  ILE F CB  1 
ATOM   7353 C  CG1 . ILE F 1 82  ? -5.260  -54.983 85.762  1.00 35.30  ? 82  ILE F CG1 1 
ATOM   7354 C  CG2 . ILE F 1 82  ? -2.760  -55.125 85.829  1.00 34.44  ? 82  ILE F CG2 1 
ATOM   7355 C  CD1 . ILE F 1 82  ? -5.432  -53.690 86.498  1.00 38.70  ? 82  ILE F CD1 1 
ATOM   7356 N  N   . ALA F 1 83  ? -2.263  -58.712 85.664  1.00 37.95  ? 83  ALA F N   1 
ATOM   7357 C  CA  . ALA F 1 83  ? -1.166  -59.567 86.104  1.00 32.33  ? 83  ALA F CA  1 
ATOM   7358 C  C   . ALA F 1 83  ? -0.237  -58.825 87.064  1.00 38.04  ? 83  ALA F C   1 
ATOM   7359 O  O   . ALA F 1 83  ? -0.001  -57.617 86.927  1.00 39.65  ? 83  ALA F O   1 
ATOM   7360 C  CB  . ALA F 1 83  ? -0.378  -60.061 84.878  1.00 25.55  ? 83  ALA F CB  1 
ATOM   7361 N  N   . ALA F 1 84  ? 0.261   -59.551 88.059  1.00 29.41  ? 84  ALA F N   1 
ATOM   7362 C  CA  . ALA F 1 84  ? 1.367   -59.055 88.862  1.00 36.12  ? 84  ALA F CA  1 
ATOM   7363 C  C   . ALA F 1 84  ? 2.546   -58.708 87.955  1.00 34.88  ? 84  ALA F C   1 
ATOM   7364 O  O   . ALA F 1 84  ? 2.763   -59.369 86.934  1.00 36.91  ? 84  ALA F O   1 
ATOM   7365 C  CB  . ALA F 1 84  ? 1.801   -60.094 89.907  1.00 32.67  ? 84  ALA F CB  1 
ATOM   7366 N  N   . PRO F 1 85  ? 3.314   -57.667 88.297  1.00 37.69  ? 85  PRO F N   1 
ATOM   7367 C  CA  . PRO F 1 85  ? 4.515   -57.333 87.520  1.00 41.69  ? 85  PRO F CA  1 
ATOM   7368 C  C   . PRO F 1 85  ? 5.487   -58.502 87.451  1.00 43.56  ? 85  PRO F C   1 
ATOM   7369 O  O   . PRO F 1 85  ? 5.535   -59.340 88.351  1.00 45.14  ? 85  PRO F O   1 
ATOM   7370 C  CB  . PRO F 1 85  ? 5.123   -56.159 88.296  1.00 40.09  ? 85  PRO F CB  1 
ATOM   7371 C  CG  . PRO F 1 85  ? 3.983   -55.571 89.039  1.00 42.38  ? 85  PRO F CG  1 
ATOM   7372 C  CD  . PRO F 1 85  ? 3.084   -56.717 89.396  1.00 39.20  ? 85  PRO F CD  1 
ATOM   7373 N  N   . SER F 1 86  ? 6.285   -58.530 86.369  1.00 48.64  ? 86  SER F N   1 
ATOM   7374 C  CA  . SER F 1 86  ? 7.196   -59.647 86.101  1.00 51.99  ? 86  SER F CA  1 
ATOM   7375 C  C   . SER F 1 86  ? 8.279   -59.797 87.163  1.00 50.85  ? 86  SER F C   1 
ATOM   7376 O  O   . SER F 1 86  ? 8.844   -60.887 87.293  1.00 55.05  ? 86  SER F O   1 
ATOM   7377 C  CB  . SER F 1 86  ? 7.871   -59.505 84.725  1.00 49.27  ? 86  SER F CB  1 
ATOM   7378 O  OG  . SER F 1 86  ? 8.327   -58.181 84.475  1.00 53.91  ? 86  SER F OG  1 
ATOM   7379 N  N   . MET F 1 87  ? 8.572   -58.746 87.930  1.00 52.41  ? 87  MET F N   1 
ATOM   7380 C  CA  . MET F 1 87  ? 9.586   -58.822 88.973  1.00 46.11  ? 87  MET F CA  1 
ATOM   7381 C  C   . MET F 1 87  ? 9.118   -58.116 90.237  1.00 49.79  ? 87  MET F C   1 
ATOM   7382 O  O   . MET F 1 87  ? 8.292   -57.193 90.206  1.00 43.39  ? 87  MET F O   1 
ATOM   7383 C  CB  . MET F 1 87  ? 10.930  -58.193 88.538  1.00 47.39  ? 87  MET F CB  1 
ATOM   7384 C  CG  . MET F 1 87  ? 11.618  -58.876 87.344  1.00 48.85  ? 87  MET F CG  1 
ATOM   7385 S  SD  . MET F 1 87  ? 12.232  -60.517 87.754  1.00 57.79  ? 87  MET F SD  1 
ATOM   7386 C  CE  . MET F 1 87  ? 13.725  -60.088 88.669  1.00 53.02  ? 87  MET F CE  1 
ATOM   7387 N  N   . ARG F 1 88  ? 9.683   -58.565 91.355  1.00 48.54  ? 88  ARG F N   1 
ATOM   7388 C  CA  . ARG F 1 88  ? 9.663   -57.814 92.605  1.00 48.90  ? 88  ARG F CA  1 
ATOM   7389 C  C   . ARG F 1 88  ? 10.761  -56.765 92.664  1.00 53.48  ? 88  ARG F C   1 
ATOM   7390 O  O   . ARG F 1 88  ? 10.514  -55.591 92.957  1.00 49.35  ? 88  ARG F O   1 
ATOM   7391 C  CB  . ARG F 1 88  ? 9.869   -58.750 93.787  1.00 58.91  ? 88  ARG F CB  1 
ATOM   7392 C  CG  . ARG F 1 88  ? 8.656   -59.493 94.004  1.00 57.15  ? 88  ARG F CG  1 
ATOM   7393 C  CD  . ARG F 1 88  ? 7.896   -58.422 94.625  1.00 62.54  ? 88  ARG F CD  1 
ATOM   7394 N  NE  . ARG F 1 88  ? 6.660   -58.356 93.901  1.00 60.19  ? 88  ARG F NE  1 
ATOM   7395 C  CZ  . ARG F 1 88  ? 5.736   -57.443 94.101  1.00 67.34  ? 88  ARG F CZ  1 
ATOM   7396 N  NH1 . ARG F 1 88  ? 5.962   -56.388 94.893  1.00 72.31  ? 88  ARG F NH1 1 
ATOM   7397 N  NH2 . ARG F 1 88  ? 4.649   -57.515 93.355  1.00 76.34  ? 88  ARG F NH2 1 
ATOM   7398 N  N   . GLU F 1 89  ? 11.996  -57.228 92.522  1.00 54.31  ? 89  GLU F N   1 
ATOM   7399 C  CA  . GLU F 1 89  ? 13.196  -56.422 92.572  1.00 50.84  ? 89  GLU F CA  1 
ATOM   7400 C  C   . GLU F 1 89  ? 13.705  -56.349 91.154  1.00 47.48  ? 89  GLU F C   1 
ATOM   7401 O  O   . GLU F 1 89  ? 13.721  -57.362 90.441  1.00 45.12  ? 89  GLU F O   1 
ATOM   7402 C  CB  . GLU F 1 89  ? 14.241  -57.052 93.494  1.00 57.25  ? 89  GLU F CB  1 
ATOM   7403 C  CG  . GLU F 1 89  ? 13.634  -57.692 94.727  1.00 60.00  ? 89  GLU F CG  1 
ATOM   7404 C  CD  . GLU F 1 89  ? 14.679  -58.250 95.652  1.00 64.94  ? 89  GLU F CD  1 
ATOM   7405 O  OE1 . GLU F 1 89  ? 14.589  -57.986 96.866  1.00 67.25  ? 89  GLU F OE1 1 
ATOM   7406 O  OE2 . GLU F 1 89  ? 15.586  -58.955 95.166  1.00 69.27  ? 89  GLU F OE2 1 
ATOM   7407 N  N   . TRP F 1 90  ? 14.085  -55.153 90.743  1.00 44.22  ? 90  TRP F N   1 
ATOM   7408 C  CA  . TRP F 1 90  ? 14.457  -54.913 89.364  1.00 44.78  ? 90  TRP F CA  1 
ATOM   7409 C  C   . TRP F 1 90  ? 15.965  -54.828 89.182  1.00 41.24  ? 90  TRP F C   1 
ATOM   7410 O  O   . TRP F 1 90  ? 16.421  -54.601 88.062  1.00 41.80  ? 90  TRP F O   1 
ATOM   7411 C  CB  . TRP F 1 90  ? 13.742  -53.652 88.860  1.00 35.50  ? 90  TRP F CB  1 
ATOM   7412 C  CG  . TRP F 1 90  ? 12.241  -53.835 88.899  1.00 39.49  ? 90  TRP F CG  1 
ATOM   7413 C  CD1 . TRP F 1 90  ? 11.376  -53.457 89.911  1.00 40.91  ? 90  TRP F CD1 1 
ATOM   7414 C  CD2 . TRP F 1 90  ? 11.428  -54.477 87.903  1.00 42.41  ? 90  TRP F CD2 1 
ATOM   7415 N  NE1 . TRP F 1 90  ? 10.084  -53.818 89.594  1.00 36.09  ? 90  TRP F NE1 1 
ATOM   7416 C  CE2 . TRP F 1 90  ? 10.083  -54.447 88.373  1.00 38.07  ? 90  TRP F CE2 1 
ATOM   7417 C  CE3 . TRP F 1 90  ? 11.701  -55.070 86.655  1.00 42.27  ? 90  TRP F CE3 1 
ATOM   7418 C  CZ2 . TRP F 1 90  ? 9.011   -54.990 87.635  1.00 35.53  ? 90  TRP F CZ2 1 
ATOM   7419 C  CZ3 . TRP F 1 90  ? 10.627  -55.617 85.914  1.00 42.54  ? 90  TRP F CZ3 1 
ATOM   7420 C  CH2 . TRP F 1 90  ? 9.295   -55.565 86.417  1.00 39.92  ? 90  TRP F CH2 1 
ATOM   7421 N  N   . GLY F 1 91  ? 16.737  -55.059 90.244  1.00 37.80  ? 91  GLY F N   1 
ATOM   7422 C  CA  . GLY F 1 91  ? 18.188  -55.061 90.127  1.00 34.41  ? 91  GLY F CA  1 
ATOM   7423 C  C   . GLY F 1 91  ? 18.738  -53.661 89.931  1.00 36.71  ? 91  GLY F C   1 
ATOM   7424 O  O   . GLY F 1 91  ? 18.397  -52.724 90.657  1.00 36.78  ? 91  GLY F O   1 
ATOM   7425 N  N   . THR F 1 92  ? 19.592  -53.507 88.925  1.00 38.59  ? 92  THR F N   1 
ATOM   7426 C  CA  . THR F 1 92  ? 20.240  -52.234 88.660  1.00 43.63  ? 92  THR F CA  1 
ATOM   7427 C  C   . THR F 1 92  ? 19.282  -51.278 87.954  1.00 47.85  ? 92  THR F C   1 
ATOM   7428 O  O   . THR F 1 92  ? 18.174  -51.650 87.540  1.00 44.41  ? 92  THR F O   1 
ATOM   7429 C  CB  . THR F 1 92  ? 21.497  -52.448 87.820  1.00 38.49  ? 92  THR F CB  1 
ATOM   7430 O  OG1 . THR F 1 92  ? 21.141  -53.114 86.601  1.00 43.40  ? 92  THR F OG1 1 
ATOM   7431 C  CG2 . THR F 1 92  ? 22.472  -53.342 88.581  1.00 41.35  ? 92  THR F CG2 1 
ATOM   7432 N  N   . GLY F 1 93  ? 19.711  -50.019 87.840  1.00 40.29  ? 93  GLY F N   1 
ATOM   7433 C  CA  . GLY F 1 93  ? 18.981  -49.086 87.001  1.00 42.62  ? 93  GLY F CA  1 
ATOM   7434 C  C   . GLY F 1 93  ? 19.000  -49.518 85.546  1.00 46.74  ? 93  GLY F C   1 
ATOM   7435 O  O   . GLY F 1 93  ? 18.004  -49.366 84.820  1.00 43.48  ? 93  GLY F O   1 
ATOM   7436 N  N   . LEU F 1 94  ? 20.128  -50.085 85.105  1.00 44.25  ? 94  LEU F N   1 
ATOM   7437 C  CA  . LEU F 1 94  ? 20.237  -50.558 83.730  1.00 42.41  ? 94  LEU F CA  1 
ATOM   7438 C  C   . LEU F 1 94  ? 19.326  -51.755 83.492  1.00 45.96  ? 94  LEU F C   1 
ATOM   7439 O  O   . LEU F 1 94  ? 18.672  -51.845 82.446  1.00 44.09  ? 94  LEU F O   1 
ATOM   7440 C  CB  . LEU F 1 94  ? 21.686  -50.908 83.406  1.00 29.92  ? 94  LEU F CB  1 
ATOM   7441 C  CG  . LEU F 1 94  ? 21.928  -51.503 82.018  1.00 44.68  ? 94  LEU F CG  1 
ATOM   7442 C  CD1 . LEU F 1 94  ? 21.618  -50.502 80.867  1.00 37.78  ? 94  LEU F CD1 1 
ATOM   7443 C  CD2 . LEU F 1 94  ? 23.358  -52.015 81.906  1.00 44.33  ? 94  LEU F CD2 1 
ATOM   7444 N  N   . GLU F 1 95  ? 19.243  -52.673 84.459  1.00 42.85  ? 95  GLU F N   1 
ATOM   7445 C  CA  . GLU F 1 95  ? 18.336  -53.802 84.287  1.00 45.52  ? 95  GLU F CA  1 
ATOM   7446 C  C   . GLU F 1 95  ? 16.873  -53.361 84.297  1.00 39.38  ? 95  GLU F C   1 
ATOM   7447 O  O   . GLU F 1 95  ? 16.057  -53.922 83.562  1.00 37.32  ? 95  GLU F O   1 
ATOM   7448 C  CB  . GLU F 1 95  ? 18.595  -54.850 85.359  1.00 45.63  ? 95  GLU F CB  1 
ATOM   7449 C  CG  . GLU F 1 95  ? 19.835  -55.710 85.093  1.00 42.22  ? 95  GLU F CG  1 
ATOM   7450 C  CD  . GLU F 1 95  ? 20.266  -56.513 86.326  1.00 46.51  ? 95  GLU F CD  1 
ATOM   7451 O  OE1 . GLU F 1 95  ? 20.360  -55.921 87.431  1.00 45.63  ? 95  GLU F OE1 1 
ATOM   7452 O  OE2 . GLU F 1 95  ? 20.496  -57.731 86.192  1.00 45.84  ? 95  GLU F OE2 1 
ATOM   7453 N  N   . ALA F 1 96  ? 16.524  -52.346 85.082  1.00 37.41  ? 96  ALA F N   1 
ATOM   7454 C  CA  . ALA F 1 96  ? 15.151  -51.858 85.032  1.00 40.61  ? 96  ALA F CA  1 
ATOM   7455 C  C   . ALA F 1 96  ? 14.836  -51.219 83.682  1.00 42.54  ? 96  ALA F C   1 
ATOM   7456 O  O   . ALA F 1 96  ? 13.723  -51.377 83.161  1.00 40.21  ? 96  ALA F O   1 
ATOM   7457 C  CB  . ALA F 1 96  ? 14.891  -50.877 86.168  1.00 35.76  ? 96  ALA F CB  1 
ATOM   7458 N  N   . LEU F 1 97  ? 15.800  -50.506 83.091  1.00 42.76  ? 97  LEU F N   1 
ATOM   7459 C  CA  . LEU F 1 97  ? 15.540  -49.887 81.792  1.00 40.41  ? 97  LEU F CA  1 
ATOM   7460 C  C   . LEU F 1 97  ? 15.455  -50.937 80.697  1.00 37.55  ? 97  LEU F C   1 
ATOM   7461 O  O   . LEU F 1 97  ? 14.660  -50.804 79.763  1.00 38.16  ? 97  LEU F O   1 
ATOM   7462 C  CB  . LEU F 1 97  ? 16.620  -48.862 81.456  1.00 39.59  ? 97  LEU F CB  1 
ATOM   7463 C  CG  . LEU F 1 97  ? 16.760  -47.681 82.410  1.00 41.59  ? 97  LEU F CG  1 
ATOM   7464 C  CD1 . LEU F 1 97  ? 18.150  -47.087 82.252  1.00 38.98  ? 97  LEU F CD1 1 
ATOM   7465 C  CD2 . LEU F 1 97  ? 15.677  -46.640 82.157  1.00 37.61  ? 97  LEU F CD2 1 
ATOM   7466 N  N   . GLN F 1 98  ? 16.270  -51.985 80.783  1.00 39.00  ? 98  GLN F N   1 
ATOM   7467 C  CA  . GLN F 1 98  ? 16.170  -53.025 79.772  1.00 38.77  ? 98  GLN F CA  1 
ATOM   7468 C  C   . GLN F 1 98  ? 14.819  -53.708 79.851  1.00 41.82  ? 98  GLN F C   1 
ATOM   7469 O  O   . GLN F 1 98  ? 14.217  -54.015 78.818  1.00 40.03  ? 98  GLN F O   1 
ATOM   7470 C  CB  . GLN F 1 98  ? 17.314  -54.025 79.909  1.00 36.93  ? 98  GLN F CB  1 
ATOM   7471 C  CG  . GLN F 1 98  ? 18.609  -53.521 79.238  1.00 47.38  ? 98  GLN F CG  1 
ATOM   7472 C  CD  . GLN F 1 98  ? 19.869  -54.111 79.856  1.00 51.05  ? 98  GLN F CD  1 
ATOM   7473 O  OE1 . GLN F 1 98  ? 19.934  -54.342 81.067  1.00 54.56  ? 98  GLN F OE1 1 
ATOM   7474 N  NE2 . GLN F 1 98  ? 20.873  -54.362 79.028  1.00 48.92  ? 98  GLN F NE2 1 
ATOM   7475 N  N   . ALA F 1 99  ? 14.299  -53.906 81.070  1.00 39.23  ? 99  ALA F N   1 
ATOM   7476 C  CA  . ALA F 1 99  ? 12.961  -54.471 81.214  1.00 37.14  ? 99  ALA F CA  1 
ATOM   7477 C  C   . ALA F 1 99  ? 11.896  -53.529 80.667  1.00 42.38  ? 99  ALA F C   1 
ATOM   7478 O  O   . ALA F 1 99  ? 10.927  -53.984 80.057  1.00 44.84  ? 99  ALA F O   1 
ATOM   7479 C  CB  . ALA F 1 99  ? 12.670  -54.797 82.673  1.00 35.86  ? 99  ALA F CB  1 
ATOM   7480 N  N   . ALA F 1 100 ? 12.053  -52.214 80.868  1.00 39.66  ? 100 ALA F N   1 
ATOM   7481 C  CA  . ALA F 1 100 ? 11.060  -51.284 80.341  1.00 43.39  ? 100 ALA F CA  1 
ATOM   7482 C  C   . ALA F 1 100 ? 11.114  -51.238 78.820  1.00 42.46  ? 100 ALA F C   1 
ATOM   7483 O  O   . ALA F 1 100 ? 10.070  -51.220 78.162  1.00 48.56  ? 100 ALA F O   1 
ATOM   7484 C  CB  . ALA F 1 100 ? 11.254  -49.884 80.931  1.00 41.49  ? 100 ALA F CB  1 
ATOM   7485 N  N   . LEU F 1 101 ? 12.315  -51.237 78.242  1.00 44.19  ? 101 LEU F N   1 
ATOM   7486 C  CA  . LEU F 1 101 ? 12.440  -51.315 76.784  1.00 48.42  ? 101 LEU F CA  1 
ATOM   7487 C  C   . LEU F 1 101 ? 11.722  -52.544 76.229  1.00 51.69  ? 101 LEU F C   1 
ATOM   7488 O  O   . LEU F 1 101 ? 11.000  -52.459 75.225  1.00 45.81  ? 101 LEU F O   1 
ATOM   7489 C  CB  . LEU F 1 101 ? 13.912  -51.345 76.371  1.00 38.51  ? 101 LEU F CB  1 
ATOM   7490 C  CG  . LEU F 1 101 ? 14.064  -51.387 74.849  1.00 39.76  ? 101 LEU F CG  1 
ATOM   7491 C  CD1 . LEU F 1 101 ? 13.488  -50.131 74.233  1.00 42.45  ? 101 LEU F CD1 1 
ATOM   7492 C  CD2 . LEU F 1 101 ? 15.494  -51.569 74.440  1.00 36.68  ? 101 LEU F CD2 1 
ATOM   7493 N  N   . ASP F 1 102 ? 11.916  -53.701 76.872  1.00 42.57  ? 102 ASP F N   1 
ATOM   7494 C  CA  . ASP F 1 102 ? 11.244  -54.915 76.426  1.00 48.00  ? 102 ASP F CA  1 
ATOM   7495 C  C   . ASP F 1 102 ? 9.744   -54.806 76.628  1.00 46.70  ? 102 ASP F C   1 
ATOM   7496 O  O   . ASP F 1 102 ? 8.958   -55.225 75.766  1.00 44.63  ? 102 ASP F O   1 
ATOM   7497 C  CB  . ASP F 1 102 ? 11.785  -56.132 77.177  1.00 45.35  ? 102 ASP F CB  1 
ATOM   7498 C  CG  . ASP F 1 102 ? 13.182  -56.504 76.745  1.00 55.32  ? 102 ASP F CG  1 
ATOM   7499 O  OD1 . ASP F 1 102 ? 13.516  -56.276 75.558  1.00 61.28  ? 102 ASP F OD1 1 
ATOM   7500 O  OD2 . ASP F 1 102 ? 13.947  -57.013 77.598  1.00 59.01  ? 102 ASP F OD2 1 
ATOM   7501 N  N   . LEU F 1 103 ? 9.329   -54.256 77.770  1.00 44.56  ? 103 LEU F N   1 
ATOM   7502 C  CA  . LEU F 1 103 ? 7.907   -54.029 78.005  1.00 49.63  ? 103 LEU F CA  1 
ATOM   7503 C  C   . LEU F 1 103 ? 7.304   -53.133 76.921  1.00 49.13  ? 103 LEU F C   1 
ATOM   7504 O  O   . LEU F 1 103 ? 6.233   -53.434 76.389  1.00 48.20  ? 103 LEU F O   1 
ATOM   7505 C  CB  . LEU F 1 103 ? 7.689   -53.430 79.395  1.00 40.68  ? 103 LEU F CB  1 
ATOM   7506 C  CG  . LEU F 1 103 ? 6.217   -53.169 79.735  1.00 47.16  ? 103 LEU F CG  1 
ATOM   7507 C  CD1 . LEU F 1 103 ? 5.415   -54.467 79.810  1.00 37.05  ? 103 LEU F CD1 1 
ATOM   7508 C  CD2 . LEU F 1 103 ? 6.061   -52.331 81.008  1.00 41.53  ? 103 LEU F CD2 1 
ATOM   7509 N  N   . GLU F 1 104 ? 7.999   -52.053 76.549  1.00 49.77  ? 104 GLU F N   1 
ATOM   7510 C  CA  . GLU F 1 104 ? 7.452   -51.140 75.549  1.00 52.06  ? 104 GLU F CA  1 
ATOM   7511 C  C   . GLU F 1 104 ? 7.396   -51.781 74.164  1.00 54.23  ? 104 GLU F C   1 
ATOM   7512 O  O   . GLU F 1 104 ? 6.447   -51.538 73.410  1.00 54.69  ? 104 GLU F O   1 
ATOM   7513 C  CB  . GLU F 1 104 ? 8.256   -49.846 75.528  1.00 45.29  ? 104 GLU F CB  1 
ATOM   7514 C  CG  . GLU F 1 104 ? 8.081   -49.042 76.802  1.00 53.93  ? 104 GLU F CG  1 
ATOM   7515 C  CD  . GLU F 1 104 ? 6.798   -48.224 76.817  1.00 64.00  ? 104 GLU F CD  1 
ATOM   7516 O  OE1 . GLU F 1 104 ? 6.539   -47.535 77.830  1.00 68.06  ? 104 GLU F OE1 1 
ATOM   7517 O  OE2 . GLU F 1 104 ? 6.050   -48.265 75.810  1.00 79.10  ? 104 GLU F OE2 1 
ATOM   7518 N  N   . LYS F 1 105 ? 8.391   -52.606 73.807  1.00 51.47  ? 105 LYS F N   1 
ATOM   7519 C  CA  . LYS F 1 105 ? 8.289   -53.369 72.565  1.00 50.80  ? 105 LYS F CA  1 
ATOM   7520 C  C   . LYS F 1 105 ? 7.117   -54.336 72.615  1.00 58.60  ? 105 LYS F C   1 
ATOM   7521 O  O   . LYS F 1 105 ? 6.485   -54.595 71.584  1.00 60.64  ? 105 LYS F O   1 
ATOM   7522 C  CB  . LYS F 1 105 ? 9.578   -54.140 72.288  1.00 49.94  ? 105 LYS F CB  1 
ATOM   7523 C  CG  . LYS F 1 105 ? 10.768  -53.294 71.842  1.00 48.17  ? 105 LYS F CG  1 
ATOM   7524 C  CD  . LYS F 1 105 ? 12.068  -54.095 72.007  1.00 52.34  ? 105 LYS F CD  1 
ATOM   7525 C  CE  . LYS F 1 105 ? 13.127  -53.657 71.022  1.00 57.45  ? 105 LYS F CE  1 
ATOM   7526 N  NZ  . LYS F 1 105 ? 12.624  -52.484 70.241  1.00 67.57  ? 105 LYS F NZ  1 
ATOM   7527 N  N   . GLN F 1 106 ? 6.810   -54.871 73.802  1.00 51.51  ? 106 GLN F N   1 
ATOM   7528 C  CA  . GLN F 1 106 ? 5.702   -55.809 73.935  1.00 53.15  ? 106 GLN F CA  1 
ATOM   7529 C  C   . GLN F 1 106 ? 4.362   -55.100 73.764  1.00 57.78  ? 106 GLN F C   1 
ATOM   7530 O  O   . GLN F 1 106 ? 3.486   -55.578 73.033  1.00 62.37  ? 106 GLN F O   1 
ATOM   7531 C  CB  . GLN F 1 106 ? 5.786   -56.529 75.291  1.00 53.08  ? 106 GLN F CB  1 
ATOM   7532 C  CG  . GLN F 1 106 ? 4.700   -57.582 75.538  1.00 63.19  ? 106 GLN F CG  1 
ATOM   7533 C  CD  . GLN F 1 106 ? 4.631   -58.089 76.995  1.00 77.46  ? 106 GLN F CD  1 
ATOM   7534 O  OE1 . GLN F 1 106 ? 5.437   -57.704 77.853  1.00 70.92  ? 106 GLN F OE1 1 
ATOM   7535 N  NE2 . GLN F 1 106 ? 3.655   -58.959 77.270  1.00 73.18  ? 106 GLN F NE2 1 
ATOM   7536 N  N   . VAL F 1 107 ? 4.188   -53.950 74.414  1.00 54.21  ? 107 VAL F N   1 
ATOM   7537 C  CA  . VAL F 1 107 ? 2.945   -53.203 74.272  1.00 54.84  ? 107 VAL F CA  1 
ATOM   7538 C  C   . VAL F 1 107 ? 2.740   -52.805 72.823  1.00 63.16  ? 107 VAL F C   1 
ATOM   7539 O  O   . VAL F 1 107 ? 1.628   -52.897 72.283  1.00 62.33  ? 107 VAL F O   1 
ATOM   7540 C  CB  . VAL F 1 107 ? 2.945   -51.970 75.196  1.00 54.98  ? 107 VAL F CB  1 
ATOM   7541 C  CG1 . VAL F 1 107 ? 1.831   -50.992 74.803  1.00 45.52  ? 107 VAL F CG1 1 
ATOM   7542 C  CG2 . VAL F 1 107 ? 2.808   -52.400 76.665  1.00 52.38  ? 107 VAL F CG2 1 
ATOM   7543 N  N   . ASN F 1 108 ? 3.813   -52.386 72.157  1.00 59.87  ? 108 ASN F N   1 
ATOM   7544 C  CA  . ASN F 1 108 ? 3.643   -51.852 70.820  1.00 66.71  ? 108 ASN F CA  1 
ATOM   7545 C  C   . ASN F 1 108 ? 3.690   -52.934 69.750  1.00 65.63  ? 108 ASN F C   1 
ATOM   7546 O  O   . ASN F 1 108 ? 3.243   -52.691 68.627  1.00 65.39  ? 108 ASN F O   1 
ATOM   7547 C  CB  . ASN F 1 108 ? 4.664   -50.742 70.567  1.00 64.09  ? 108 ASN F CB  1 
ATOM   7548 C  CG  . ASN F 1 108 ? 4.178   -49.403 71.115  1.00 82.92  ? 108 ASN F CG  1 
ATOM   7549 O  OD1 . ASN F 1 108 ? 3.331   -48.742 70.499  1.00 89.38  ? 108 ASN F OD1 1 
ATOM   7550 N  ND2 . ASN F 1 108 ? 4.707   -48.995 72.277  1.00 73.40  ? 108 ASN F ND2 1 
ATOM   7551 N  N   . GLN F 1 109 ? 4.184   -54.124 70.076  1.00 63.13  ? 109 GLN F N   1 
ATOM   7552 C  CA  . GLN F 1 109 ? 3.876   -55.290 69.260  1.00 64.59  ? 109 GLN F CA  1 
ATOM   7553 C  C   . GLN F 1 109 ? 2.368   -55.520 69.212  1.00 69.13  ? 109 GLN F C   1 
ATOM   7554 O  O   . GLN F 1 109 ? 1.759   -55.560 68.134  1.00 67.61  ? 109 GLN F O   1 
ATOM   7555 C  CB  . GLN F 1 109 ? 4.590   -56.517 69.823  1.00 66.75  ? 109 GLN F CB  1 
ATOM   7556 C  CG  . GLN F 1 109 ? 4.582   -57.689 68.887  1.00 64.11  ? 109 GLN F CG  1 
ATOM   7557 C  CD  . GLN F 1 109 ? 4.988   -57.272 67.497  1.00 71.82  ? 109 GLN F CD  1 
ATOM   7558 O  OE1 . GLN F 1 109 ? 6.055   -56.680 67.299  1.00 70.84  ? 109 GLN F OE1 1 
ATOM   7559 N  NE2 . GLN F 1 109 ? 4.126   -57.553 66.520  1.00 66.67  ? 109 GLN F NE2 1 
ATOM   7560 N  N   . SER F 1 110 ? 1.752   -55.671 70.388  1.00 65.43  ? 110 SER F N   1 
ATOM   7561 C  CA  . SER F 1 110 ? 0.305   -55.737 70.568  1.00 61.86  ? 110 SER F CA  1 
ATOM   7562 C  C   . SER F 1 110 ? -0.433  -54.683 69.742  1.00 61.90  ? 110 SER F C   1 
ATOM   7563 O  O   . SER F 1 110 ? -1.453  -54.975 69.105  1.00 59.13  ? 110 SER F O   1 
ATOM   7564 C  CB  . SER F 1 110 ? -0.019  -55.572 72.057  1.00 60.30  ? 110 SER F CB  1 
ATOM   7565 O  OG  . SER F 1 110 ? -1.267  -56.145 72.394  1.00 57.63  ? 110 SER F OG  1 
ATOM   7566 N  N   . LEU F 1 111 ? 0.079   -53.452 69.748  1.00 61.66  ? 111 LEU F N   1 
ATOM   7567 C  CA  . LEU F 1 111 ? -0.566  -52.380 68.998  1.00 63.66  ? 111 LEU F CA  1 
ATOM   7568 C  C   . LEU F 1 111 ? -0.503  -52.648 67.502  1.00 67.54  ? 111 LEU F C   1 
ATOM   7569 O  O   . LEU F 1 111 ? -1.499  -52.476 66.791  1.00 69.17  ? 111 LEU F O   1 
ATOM   7570 C  CB  . LEU F 1 111 ? 0.080   -51.032 69.324  1.00 60.08  ? 111 LEU F CB  1 
ATOM   7571 C  CG  . LEU F 1 111 ? -0.672  -50.172 70.327  1.00 65.53  ? 111 LEU F CG  1 
ATOM   7572 C  CD1 . LEU F 1 111 ? 0.231   -49.117 70.927  1.00 73.14  ? 111 LEU F CD1 1 
ATOM   7573 C  CD2 . LEU F 1 111 ? -1.844  -49.526 69.629  1.00 70.61  ? 111 LEU F CD2 1 
ATOM   7574 N  N   . LEU F 1 112 ? 0.669   -53.060 67.000  1.00 66.01  ? 112 LEU F N   1 
ATOM   7575 C  CA  . LEU F 1 112 ? 0.812   -53.283 65.565  1.00 66.37  ? 112 LEU F CA  1 
ATOM   7576 C  C   . LEU F 1 112 ? 0.036   -54.518 65.107  1.00 67.94  ? 112 LEU F C   1 
ATOM   7577 O  O   . LEU F 1 112 ? -0.355  -54.585 63.935  1.00 61.85  ? 112 LEU F O   1 
ATOM   7578 C  CB  . LEU F 1 112 ? 2.305   -53.355 65.168  1.00 63.57  ? 112 LEU F CB  1 
ATOM   7579 C  CG  . LEU F 1 112 ? 3.260   -52.207 65.628  1.00 80.80  ? 112 LEU F CG  1 
ATOM   7580 C  CD1 . LEU F 1 112 ? 4.639   -52.214 64.935  1.00 70.74  ? 112 LEU F CD1 1 
ATOM   7581 C  CD2 . LEU F 1 112 ? 2.648   -50.781 65.551  1.00 76.25  ? 112 LEU F CD2 1 
ATOM   7582 N  N   . GLU F 1 113 ? -0.250  -55.464 66.012  1.00 60.81  ? 113 GLU F N   1 
ATOM   7583 C  CA  . GLU F 1 113 ? -1.183  -56.535 65.671  1.00 61.33  ? 113 GLU F CA  1 
ATOM   7584 C  C   . GLU F 1 113 ? -2.611  -56.010 65.601  1.00 69.19  ? 113 GLU F C   1 
ATOM   7585 O  O   . GLU F 1 113 ? -3.374  -56.371 64.696  1.00 65.87  ? 113 GLU F O   1 
ATOM   7586 C  CB  . GLU F 1 113 ? -1.083  -57.671 66.680  1.00 57.19  ? 113 GLU F CB  1 
ATOM   7587 C  CG  . GLU F 1 113 ? 0.298   -58.259 66.765  1.00 65.98  ? 113 GLU F CG  1 
ATOM   7588 C  CD  . GLU F 1 113 ? 0.452   -59.266 67.892  1.00 78.24  ? 113 GLU F CD  1 
ATOM   7589 O  OE1 . GLU F 1 113 ? 1.429   -60.051 67.831  1.00 83.19  ? 113 GLU F OE1 1 
ATOM   7590 O  OE2 . GLU F 1 113 ? -0.395  -59.276 68.822  1.00 79.09  ? 113 GLU F OE2 1 
ATOM   7591 N  N   . LEU F 1 114 ? -2.982  -55.149 66.549  1.00 69.92  ? 114 LEU F N   1 
ATOM   7592 C  CA  . LEU F 1 114 ? -4.263  -54.457 66.499  1.00 69.35  ? 114 LEU F CA  1 
ATOM   7593 C  C   . LEU F 1 114 ? -4.414  -53.603 65.241  1.00 69.99  ? 114 LEU F C   1 
ATOM   7594 O  O   . LEU F 1 114 ? -5.542  -53.251 64.873  1.00 68.30  ? 114 LEU F O   1 
ATOM   7595 C  CB  . LEU F 1 114 ? -4.405  -53.598 67.759  1.00 68.08  ? 114 LEU F CB  1 
ATOM   7596 C  CG  . LEU F 1 114 ? -5.685  -52.805 68.012  1.00 69.18  ? 114 LEU F CG  1 
ATOM   7597 C  CD1 . LEU F 1 114 ? -6.813  -53.742 68.337  1.00 63.38  ? 114 LEU F CD1 1 
ATOM   7598 C  CD2 . LEU F 1 114 ? -5.474  -51.816 69.140  1.00 67.24  ? 114 LEU F CD2 1 
ATOM   7599 N  N   . HIS F 1 115 ? -3.305  -53.255 64.578  1.00 71.75  ? 115 HIS F N   1 
ATOM   7600 C  CA  . HIS F 1 115 ? -3.376  -52.463 63.355  1.00 67.92  ? 115 HIS F CA  1 
ATOM   7601 C  C   . HIS F 1 115 ? -3.615  -53.339 62.132  1.00 67.09  ? 115 HIS F C   1 
ATOM   7602 O  O   . HIS F 1 115 ? -4.375  -52.952 61.239  1.00 71.46  ? 115 HIS F O   1 
ATOM   7603 C  CB  . HIS F 1 115 ? -2.102  -51.639 63.170  1.00 62.38  ? 115 HIS F CB  1 
ATOM   7604 C  CG  . HIS F 1 115 ? -2.165  -50.675 62.022  1.00 67.58  ? 115 HIS F CG  1 
ATOM   7605 N  ND1 . HIS F 1 115 ? -2.476  -49.339 62.184  1.00 68.99  ? 115 HIS F ND1 1 
ATOM   7606 C  CD2 . HIS F 1 115 ? -1.953  -50.852 60.695  1.00 59.31  ? 115 HIS F CD2 1 
ATOM   7607 C  CE1 . HIS F 1 115 ? -2.452  -48.736 61.008  1.00 63.71  ? 115 HIS F CE1 1 
ATOM   7608 N  NE2 . HIS F 1 115 ? -2.148  -49.635 60.088  1.00 63.35  ? 115 HIS F NE2 1 
ATOM   7609 N  N   . SER F 1 116 ? -2.966  -54.507 62.062  1.00 62.19  ? 116 SER F N   1 
ATOM   7610 C  CA  . SER F 1 116 ? -3.218  -55.415 60.947  1.00 68.10  ? 116 SER F CA  1 
ATOM   7611 C  C   . SER F 1 116 ? -4.684  -55.828 60.890  1.00 74.39  ? 116 SER F C   1 
ATOM   7612 O  O   . SER F 1 116 ? -5.284  -55.868 59.808  1.00 77.59  ? 116 SER F O   1 
ATOM   7613 C  CB  . SER F 1 116 ? -2.347  -56.662 61.053  1.00 68.82  ? 116 SER F CB  1 
ATOM   7614 O  OG  . SER F 1 116 ? -3.105  -57.728 61.609  1.00 73.29  ? 116 SER F OG  1 
ATOM   7615 N  N   . THR F 1 117 ? -5.277  -56.149 62.045  1.00 75.30  ? 117 THR F N   1 
ATOM   7616 C  CA  . THR F 1 117 ? -6.656  -56.632 62.057  1.00 76.38  ? 117 THR F CA  1 
ATOM   7617 C  C   . THR F 1 117 ? -7.664  -55.501 61.874  1.00 73.08  ? 117 THR F C   1 
ATOM   7618 O  O   . THR F 1 117 ? -8.731  -55.721 61.292  1.00 74.08  ? 117 THR F O   1 
ATOM   7619 C  CB  . THR F 1 117 ? -6.948  -57.397 63.351  1.00 72.00  ? 117 THR F CB  1 
ATOM   7620 O  OG1 . THR F 1 117 ? -6.614  -56.577 64.472  1.00 76.08  ? 117 THR F OG1 1 
ATOM   7621 C  CG2 . THR F 1 117 ? -6.126  -58.690 63.406  1.00 70.20  ? 117 THR F CG2 1 
ATOM   7622 N  N   . ALA F 1 118 ? -7.360  -54.291 62.352  1.00 70.36  ? 118 ALA F N   1 
ATOM   7623 C  CA  . ALA F 1 118 ? -8.170  -53.145 61.947  1.00 72.54  ? 118 ALA F CA  1 
ATOM   7624 C  C   . ALA F 1 118 ? -8.014  -52.835 60.462  1.00 73.08  ? 118 ALA F C   1 
ATOM   7625 O  O   . ALA F 1 118 ? -8.849  -52.123 59.898  1.00 74.68  ? 118 ALA F O   1 
ATOM   7626 C  CB  . ALA F 1 118 ? -7.811  -51.917 62.774  1.00 67.32  ? 118 ALA F CB  1 
ATOM   7627 N  N   . SER F 1 119 ? -6.951  -53.345 59.829  1.00 77.21  ? 119 SER F N   1 
ATOM   7628 C  CA  . SER F 1 119 ? -6.798  -53.286 58.380  1.00 76.81  ? 119 SER F CA  1 
ATOM   7629 C  C   . SER F 1 119 ? -7.538  -54.436 57.706  1.00 78.29  ? 119 SER F C   1 
ATOM   7630 O  O   . SER F 1 119 ? -8.203  -54.231 56.683  1.00 82.14  ? 119 SER F O   1 
ATOM   7631 C  CB  . SER F 1 119 ? -5.312  -53.319 58.002  1.00 66.73  ? 119 SER F CB  1 
ATOM   7632 O  OG  . SER F 1 119 ? -4.703  -52.049 58.146  1.00 73.79  ? 119 SER F OG  1 
ATOM   7633 N  N   . GLY F 1 120 ? -7.438  -55.644 58.274  1.00 75.69  ? 120 GLY F N   1 
ATOM   7634 C  CA  . GLY F 1 120 ? -8.073  -56.838 57.737  1.00 76.24  ? 120 GLY F CA  1 
ATOM   7635 C  C   . GLY F 1 120 ? -9.585  -56.853 57.838  1.00 78.30  ? 120 GLY F C   1 
ATOM   7636 O  O   . GLY F 1 120 ? -10.222 -57.710 57.217  1.00 84.75  ? 120 GLY F O   1 
ATOM   7637 N  N   . ASN F 1 121 ? -10.167 -55.945 58.617  1.00 80.67  ? 121 ASN F N   1 
ATOM   7638 C  CA  . ASN F 1 121 ? -11.610 -55.762 58.686  1.00 78.89  ? 121 ASN F CA  1 
ATOM   7639 C  C   . ASN F 1 121 ? -12.043 -54.466 58.021  1.00 83.24  ? 121 ASN F C   1 
ATOM   7640 O  O   . ASN F 1 121 ? -13.219 -54.099 58.108  1.00 87.11  ? 121 ASN F O   1 
ATOM   7641 C  CB  . ASN F 1 121 ? -12.098 -55.780 60.141  1.00 79.17  ? 121 ASN F CB  1 
ATOM   7642 C  CG  . ASN F 1 121 ? -12.178 -57.184 60.725  1.00 80.19  ? 121 ASN F CG  1 
ATOM   7643 O  OD1 . ASN F 1 121 ? -12.750 -58.097 60.124  1.00 88.25  ? 121 ASN F OD1 1 
ATOM   7644 N  ND2 . ASN F 1 121 ? -11.624 -57.352 61.915  1.00 80.36  ? 121 ASN F ND2 1 
ATOM   7645 N  N   . ASN F 1 122 ? -11.119 -53.767 57.363  1.00 80.73  ? 122 ASN F N   1 
ATOM   7646 C  CA  . ASN F 1 122 ? -11.393 -52.470 56.750  1.00 82.24  ? 122 ASN F CA  1 
ATOM   7647 C  C   . ASN F 1 122 ? -12.174 -51.571 57.707  1.00 84.93  ? 122 ASN F C   1 
ATOM   7648 O  O   . ASN F 1 122 ? -13.199 -50.980 57.359  1.00 85.09  ? 122 ASN F O   1 
ATOM   7649 C  CB  . ASN F 1 122 ? -12.114 -52.631 55.409  1.00 84.78  ? 122 ASN F CB  1 
ATOM   7650 C  CG  . ASN F 1 122 ? -11.154 -52.558 54.224  1.00 88.85  ? 122 ASN F CG  1 
ATOM   7651 O  OD1 . ASN F 1 122 ? -10.076 -53.161 54.247  1.00 85.48  ? 122 ASN F OD1 1 
ATOM   7652 N  ND2 . ASN F 1 122 ? -11.533 -51.805 53.194  1.00 85.74  ? 122 ASN F ND2 1 
ATOM   7653 N  N   . ASP F 1 123 ? -11.689 -51.511 58.951  1.00 89.92  ? 123 ASP F N   1 
ATOM   7654 C  CA  . ASP F 1 123 ? -12.143 -50.546 59.944  1.00 88.13  ? 123 ASP F CA  1 
ATOM   7655 C  C   . ASP F 1 123 ? -11.201 -49.360 59.828  1.00 77.12  ? 123 ASP F C   1 
ATOM   7656 O  O   . ASP F 1 123 ? -10.173 -49.323 60.514  1.00 80.82  ? 123 ASP F O   1 
ATOM   7657 C  CB  . ASP F 1 123 ? -12.120 -51.131 61.364  1.00 78.36  ? 123 ASP F CB  1 
ATOM   7658 C  CG  . ASP F 1 123 ? -12.723 -50.184 62.407  1.00 79.24  ? 123 ASP F CG  1 
ATOM   7659 O  OD1 . ASP F 1 123 ? -13.116 -50.681 63.491  1.00 84.74  ? 123 ASP F OD1 1 
ATOM   7660 O  OD2 . ASP F 1 123 ? -12.826 -48.958 62.143  1.00 72.07  ? 123 ASP F OD2 1 
ATOM   7661 N  N   . PRO F 1 124 ? -11.507 -48.384 58.974  1.00 77.59  ? 124 PRO F N   1 
ATOM   7662 C  CA  . PRO F 1 124 ? -10.506 -47.348 58.687  1.00 77.86  ? 124 PRO F CA  1 
ATOM   7663 C  C   . PRO F 1 124 ? -10.086 -46.577 59.919  1.00 77.17  ? 124 PRO F C   1 
ATOM   7664 O  O   . PRO F 1 124 ? -8.900  -46.269 60.087  1.00 80.49  ? 124 PRO F O   1 
ATOM   7665 C  CB  . PRO F 1 124 ? -11.224 -46.445 57.675  1.00 74.42  ? 124 PRO F CB  1 
ATOM   7666 C  CG  . PRO F 1 124 ? -12.682 -46.614 58.007  1.00 72.21  ? 124 PRO F CG  1 
ATOM   7667 C  CD  . PRO F 1 124 ? -12.825 -48.057 58.404  1.00 79.06  ? 124 PRO F CD  1 
ATOM   7668 N  N   . CYS F 1 125 ? -11.022 -46.283 60.811  1.00 80.31  ? 125 CYS F N   1 
ATOM   7669 C  CA  . CYS F 1 125 ? -10.786 -45.299 61.850  1.00 78.49  ? 125 CYS F CA  1 
ATOM   7670 C  C   . CYS F 1 125 ? -10.354 -45.908 63.180  1.00 73.89  ? 125 CYS F C   1 
ATOM   7671 O  O   . CYS F 1 125 ? -10.110 -45.172 64.140  1.00 69.22  ? 125 CYS F O   1 
ATOM   7672 C  CB  . CYS F 1 125 ? -12.017 -44.420 61.987  1.00 81.41  ? 125 CYS F CB  1 
ATOM   7673 S  SG  . CYS F 1 125 ? -11.864 -42.970 60.883  1.00 81.42  ? 125 CYS F SG  1 
ATOM   7674 N  N   . LEU F 1 126 ? -10.190 -47.228 63.232  1.00 71.49  ? 126 LEU F N   1 
ATOM   7675 C  CA  . LEU F 1 126 ? -9.394  -47.839 64.284  1.00 69.90  ? 126 LEU F CA  1 
ATOM   7676 C  C   . LEU F 1 126 ? -7.905  -47.665 63.990  1.00 76.24  ? 126 LEU F C   1 
ATOM   7677 O  O   . LEU F 1 126 ? -7.143  -47.197 64.847  1.00 74.11  ? 126 LEU F O   1 
ATOM   7678 C  CB  . LEU F 1 126 ? -9.774  -49.314 64.417  1.00 63.94  ? 126 LEU F CB  1 
ATOM   7679 C  CG  . LEU F 1 126 ? -9.121  -50.096 65.554  1.00 69.23  ? 126 LEU F CG  1 
ATOM   7680 C  CD1 . LEU F 1 126 ? -9.062  -49.240 66.798  1.00 75.39  ? 126 LEU F CD1 1 
ATOM   7681 C  CD2 . LEU F 1 126 ? -9.860  -51.393 65.835  1.00 66.03  ? 126 LEU F CD2 1 
ATOM   7682 N  N   . THR F 1 127 ? -7.487  -48.005 62.763  1.00 78.15  ? 127 THR F N   1 
ATOM   7683 C  CA  . THR F 1 127 ? -6.106  -47.770 62.348  1.00 73.64  ? 127 THR F CA  1 
ATOM   7684 C  C   . THR F 1 127 ? -5.725  -46.303 62.489  1.00 72.51  ? 127 THR F C   1 
ATOM   7685 O  O   . THR F 1 127 ? -4.588  -45.985 62.852  1.00 72.46  ? 127 THR F O   1 
ATOM   7686 C  CB  . THR F 1 127 ? -5.890  -48.219 60.901  1.00 71.14  ? 127 THR F CB  1 
ATOM   7687 O  OG1 . THR F 1 127 ? -6.616  -47.354 60.022  1.00 75.74  ? 127 THR F OG1 1 
ATOM   7688 C  CG2 . THR F 1 127 ? -6.319  -49.655 60.680  1.00 67.40  ? 127 THR F CG2 1 
ATOM   7689 N  N   . LYS F 1 128 ? -6.658  -45.394 62.195  1.00 72.77  ? 128 LYS F N   1 
ATOM   7690 C  CA  . LYS F 1 128 ? -6.377  -43.973 62.359  1.00 72.81  ? 128 LYS F CA  1 
ATOM   7691 C  C   . LYS F 1 128 ? -5.917  -43.672 63.781  1.00 79.57  ? 128 LYS F C   1 
ATOM   7692 O  O   . LYS F 1 128 ? -4.848  -43.087 63.983  1.00 85.38  ? 128 LYS F O   1 
ATOM   7693 C  CB  . LYS F 1 128 ? -7.610  -43.143 61.986  1.00 76.99  ? 128 LYS F CB  1 
ATOM   7694 C  CG  . LYS F 1 128 ? -7.383  -41.631 61.978  1.00 76.44  ? 128 LYS F CG  1 
ATOM   7695 C  CD  . LYS F 1 128 ? -7.669  -40.997 63.337  1.00 86.82  ? 128 LYS F CD  1 
ATOM   7696 C  CE  . LYS F 1 128 ? -7.885  -39.492 63.237  1.00 89.26  ? 128 LYS F CE  1 
ATOM   7697 N  NZ  . LYS F 1 128 ? -9.270  -39.140 62.834  1.00 89.95  ? 128 LYS F NZ  1 
ATOM   7698 N  N   . LEU F 1 129 ? -6.699  -44.083 64.786  1.00 76.15  ? 129 LEU F N   1 
ATOM   7699 C  CA  . LEU F 1 129 ? -6.326  -43.768 66.163  1.00 74.59  ? 129 LEU F CA  1 
ATOM   7700 C  C   . LEU F 1 129 ? -5.050  -44.492 66.569  1.00 79.21  ? 129 LEU F C   1 
ATOM   7701 O  O   . LEU F 1 129 ? -4.201  -43.916 67.259  1.00 83.92  ? 129 LEU F O   1 
ATOM   7702 C  CB  . LEU F 1 129 ? -7.453  -44.110 67.136  1.00 71.41  ? 129 LEU F CB  1 
ATOM   7703 C  CG  . LEU F 1 129 ? -6.995  -44.140 68.601  1.00 68.20  ? 129 LEU F CG  1 
ATOM   7704 C  CD1 . LEU F 1 129 ? -6.519  -42.744 69.043  1.00 78.24  ? 129 LEU F CD1 1 
ATOM   7705 C  CD2 . LEU F 1 129 ? -8.075  -44.640 69.513  1.00 55.95  ? 129 LEU F CD2 1 
ATOM   7706 N  N   . LEU F 1 130 ? -4.899  -45.757 66.165  1.00 75.20  ? 130 LEU F N   1 
ATOM   7707 C  CA  . LEU F 1 130 ? -3.678  -46.485 66.496  1.00 74.90  ? 130 LEU F CA  1 
ATOM   7708 C  C   . LEU F 1 130 ? -2.451  -45.690 66.072  1.00 83.24  ? 130 LEU F C   1 
ATOM   7709 O  O   . LEU F 1 130 ? -1.590  -45.363 66.895  1.00 85.71  ? 130 LEU F O   1 
ATOM   7710 C  CB  . LEU F 1 130 ? -3.682  -47.865 65.843  1.00 62.68  ? 130 LEU F CB  1 
ATOM   7711 C  CG  . LEU F 1 130 ? -4.828  -48.754 66.292  1.00 70.36  ? 130 LEU F CG  1 
ATOM   7712 C  CD1 . LEU F 1 130 ? -4.545  -50.183 65.901  1.00 69.29  ? 130 LEU F CD1 1 
ATOM   7713 C  CD2 . LEU F 1 130 ? -5.041  -48.623 67.795  1.00 75.69  ? 130 LEU F CD2 1 
ATOM   7714 N  N   . GLU F 1 131 ? -2.375  -45.323 64.797  1.00 78.98  ? 131 GLU F N   1 
ATOM   7715 C  CA  . GLU F 1 131 ? -1.218  -44.553 64.368  1.00 85.24  ? 131 GLU F CA  1 
ATOM   7716 C  C   . GLU F 1 131 ? -1.259  -43.131 64.927  1.00 94.71  ? 131 GLU F C   1 
ATOM   7717 O  O   . GLU F 1 131 ? -0.254  -42.651 65.468  1.00 101.86 ? 131 GLU F O   1 
ATOM   7718 C  CB  . GLU F 1 131 ? -1.100  -44.563 62.836  1.00 87.38  ? 131 GLU F CB  1 
ATOM   7719 C  CG  . GLU F 1 131 ? -2.233  -43.904 62.041  1.00 84.77  ? 131 GLU F CG  1 
ATOM   7720 C  CD  . GLU F 1 131 ? -2.316  -44.422 60.598  1.00 87.23  ? 131 GLU F CD  1 
ATOM   7721 O  OE1 . GLU F 1 131 ? -2.009  -45.621 60.363  1.00 80.82  ? 131 GLU F OE1 1 
ATOM   7722 O  OE2 . GLU F 1 131 ? -2.693  -43.630 59.700  1.00 90.19  ? 131 GLU F OE2 1 
ATOM   7723 N  N   . ASP F 1 132 ? -2.416  -42.458 64.865  1.00 89.27  ? 132 ASP F N   1 
ATOM   7724 C  CA  . ASP F 1 132 ? -2.428  -41.013 65.101  1.00 93.30  ? 132 ASP F CA  1 
ATOM   7725 C  C   . ASP F 1 132 ? -2.088  -40.619 66.535  1.00 94.52  ? 132 ASP F C   1 
ATOM   7726 O  O   . ASP F 1 132 ? -1.743  -39.456 66.769  1.00 97.71  ? 132 ASP F O   1 
ATOM   7727 C  CB  . ASP F 1 132 ? -3.779  -40.405 64.720  1.00 90.98  ? 132 ASP F CB  1 
ATOM   7728 C  CG  . ASP F 1 132 ? -3.770  -39.804 63.317  1.00 99.23  ? 132 ASP F CG  1 
ATOM   7729 O  OD1 . ASP F 1 132 ? -2.670  -39.492 62.797  1.00 95.17  ? 132 ASP F OD1 1 
ATOM   7730 O  OD2 . ASP F 1 132 ? -4.863  -39.642 62.733  1.00 94.83  ? 132 ASP F OD2 1 
ATOM   7731 N  N   . GLU F 1 133 ? -2.180  -41.534 67.501  1.00 95.96  ? 133 GLU F N   1 
ATOM   7732 C  CA  . GLU F 1 133 ? -1.764  -41.208 68.865  1.00 98.02  ? 133 GLU F CA  1 
ATOM   7733 C  C   . GLU F 1 133 ? -0.921  -42.281 69.542  1.00 92.65  ? 133 GLU F C   1 
ATOM   7734 O  O   . GLU F 1 133 ? -0.316  -41.986 70.580  1.00 84.60  ? 133 GLU F O   1 
ATOM   7735 C  CB  . GLU F 1 133 ? -2.986  -40.902 69.755  1.00 93.84  ? 133 GLU F CB  1 
ATOM   7736 C  CG  . GLU F 1 133 ? -3.977  -39.904 69.151  1.00 102.95 ? 133 GLU F CG  1 
ATOM   7737 C  CD  . GLU F 1 133 ? -3.552  -38.442 69.344  1.00 111.31 ? 133 GLU F CD  1 
ATOM   7738 O  OE1 . GLU F 1 133 ? -3.330  -37.750 68.320  1.00 111.18 ? 133 GLU F OE1 1 
ATOM   7739 O  OE2 . GLU F 1 133 ? -3.454  -37.979 70.508  1.00 105.35 ? 133 GLU F OE2 1 
ATOM   7740 N  N   . TYR F 1 134 ? -0.845  -43.500 69.003  1.00 88.28  ? 134 TYR F N   1 
ATOM   7741 C  CA  . TYR F 1 134 ? -0.142  -44.592 69.665  1.00 91.01  ? 134 TYR F CA  1 
ATOM   7742 C  C   . TYR F 1 134 ? 0.997   -45.127 68.819  1.00 93.54  ? 134 TYR F C   1 
ATOM   7743 O  O   . TYR F 1 134 ? 1.484   -46.238 69.057  1.00 91.11  ? 134 TYR F O   1 
ATOM   7744 C  CB  . TYR F 1 134 ? -1.133  -45.686 70.065  1.00 83.36  ? 134 TYR F CB  1 
ATOM   7745 C  CG  . TYR F 1 134 ? -1.825  -45.156 71.263  1.00 85.31  ? 134 TYR F CG  1 
ATOM   7746 C  CD1 . TYR F 1 134 ? -2.934  -44.324 71.135  1.00 78.14  ? 134 TYR F CD1 1 
ATOM   7747 C  CD2 . TYR F 1 134 ? -1.274  -45.347 72.519  1.00 83.94  ? 134 TYR F CD2 1 
ATOM   7748 C  CE1 . TYR F 1 134 ? -3.518  -43.765 72.234  1.00 81.75  ? 134 TYR F CE1 1 
ATOM   7749 C  CE2 . TYR F 1 134 ? -1.846  -44.799 73.623  1.00 84.83  ? 134 TYR F CE2 1 
ATOM   7750 C  CZ  . TYR F 1 134 ? -2.971  -44.008 73.486  1.00 84.69  ? 134 TYR F CZ  1 
ATOM   7751 O  OH  . TYR F 1 134 ? -3.534  -43.457 74.617  1.00 78.45  ? 134 TYR F OH  1 
ATOM   7752 N  N   . CYS F 1 135 ? 1.447   -44.325 67.857  1.00 96.46  ? 135 CYS F N   1 
ATOM   7753 C  CA  . CYS F 1 135 ? 2.587   -44.675 67.025  1.00 99.11  ? 135 CYS F CA  1 
ATOM   7754 C  C   . CYS F 1 135 ? 3.587   -43.525 66.941  1.00 95.34  ? 135 CYS F C   1 
ATOM   7755 O  O   . CYS F 1 135 ? 4.787   -43.763 66.777  1.00 91.12  ? 135 CYS F O   1 
ATOM   7756 C  CB  . CYS F 1 135 ? 2.114   -45.128 65.632  1.00 96.86  ? 135 CYS F CB  1 
ATOM   7757 S  SG  . CYS F 1 135 ? 3.318   -44.954 64.288  1.00 88.21  ? 135 CYS F SG  1 
ATOM   7758 N  N   . GLU F 1 136 ? 3.145   -42.274 67.073  1.00 92.32  ? 136 GLU F N   1 
ATOM   7759 C  CA  . GLU F 1 136 ? 4.102   -41.203 66.812  1.00 96.17  ? 136 GLU F CA  1 
ATOM   7760 C  C   . GLU F 1 136 ? 5.014   -40.963 68.008  1.00 100.92 ? 136 GLU F C   1 
ATOM   7761 O  O   . GLU F 1 136 ? 6.143   -40.488 67.847  1.00 101.40 ? 136 GLU F O   1 
ATOM   7762 C  CB  . GLU F 1 136 ? 3.396   -39.920 66.381  1.00 103.48 ? 136 GLU F CB  1 
ATOM   7763 C  CG  . GLU F 1 136 ? 4.389   -38.915 65.803  1.00 105.15 ? 136 GLU F CG  1 
ATOM   7764 C  CD  . GLU F 1 136 ? 3.804   -38.073 64.686  1.00 112.22 ? 136 GLU F CD  1 
ATOM   7765 O  OE1 . GLU F 1 136 ? 4.521   -37.872 63.677  1.00 109.62 ? 136 GLU F OE1 1 
ATOM   7766 O  OE2 . GLU F 1 136 ? 2.645   -37.620 64.809  1.00 106.67 ? 136 GLU F OE2 1 
ATOM   7767 N  N   . GLU F 1 137 ? 4.565   -41.296 69.215  1.00 100.03 ? 137 GLU F N   1 
ATOM   7768 C  CA  . GLU F 1 137 ? 5.511   -41.471 70.306  1.00 92.97  ? 137 GLU F CA  1 
ATOM   7769 C  C   . GLU F 1 137 ? 5.629   -42.939 70.714  1.00 92.97  ? 137 GLU F C   1 
ATOM   7770 O  O   . GLU F 1 137 ? 6.235   -43.240 71.745  1.00 93.24  ? 137 GLU F O   1 
ATOM   7771 C  CB  . GLU F 1 137 ? 5.179   -40.576 71.515  1.00 96.39  ? 137 GLU F CB  1 
ATOM   7772 C  CG  . GLU F 1 137 ? 6.385   -40.496 72.487  1.00 94.84  ? 137 GLU F CG  1 
ATOM   7773 C  CD  . GLU F 1 137 ? 6.367   -39.370 73.502  1.00 93.11  ? 137 GLU F CD  1 
ATOM   7774 O  OE1 . GLU F 1 137 ? 7.480   -38.914 73.847  1.00 92.09  ? 137 GLU F OE1 1 
ATOM   7775 O  OE2 . GLU F 1 137 ? 5.285   -38.966 73.977  1.00 98.03  ? 137 GLU F OE2 1 
ATOM   7776 N  N   . GLN F 1 138 ? 5.081   -43.870 69.924  1.00 89.47  ? 138 GLN F N   1 
ATOM   7777 C  CA  . GLN F 1 138 ? 5.733   -45.173 69.824  1.00 89.56  ? 138 GLN F CA  1 
ATOM   7778 C  C   . GLN F 1 138 ? 7.224   -44.962 69.583  1.00 88.25  ? 138 GLN F C   1 
ATOM   7779 O  O   . GLN F 1 138 ? 8.069   -45.430 70.354  1.00 78.40  ? 138 GLN F O   1 
ATOM   7780 C  CB  . GLN F 1 138 ? 5.118   -45.999 68.688  1.00 90.23  ? 138 GLN F CB  1 
ATOM   7781 C  CG  . GLN F 1 138 ? 5.352   -47.508 68.714  1.00 100.27 ? 138 GLN F CG  1 
ATOM   7782 C  CD  . GLN F 1 138 ? 4.432   -48.295 67.746  1.00 98.78  ? 138 GLN F CD  1 
ATOM   7783 O  OE1 . GLN F 1 138 ? 4.806   -49.369 67.253  1.00 95.05  ? 138 GLN F OE1 1 
ATOM   7784 N  NE2 . GLN F 1 138 ? 3.237   -47.759 67.473  1.00 91.04  ? 138 GLN F NE2 1 
ATOM   7785 N  N   . CYS F 1 139 ? 7.544   -44.182 68.540  1.00 91.52  ? 139 CYS F N   1 
ATOM   7786 C  CA  . CYS F 1 139 ? 8.920   -43.886 68.151  1.00 82.53  ? 139 CYS F CA  1 
ATOM   7787 C  C   . CYS F 1 139 ? 9.714   -43.257 69.290  1.00 79.64  ? 139 CYS F C   1 
ATOM   7788 O  O   . CYS F 1 139 ? 10.782  -43.759 69.660  1.00 80.39  ? 139 CYS F O   1 
ATOM   7789 C  CB  . CYS F 1 139 ? 8.910   -42.955 66.932  1.00 85.83  ? 139 CYS F CB  1 
ATOM   7790 S  SG  . CYS F 1 139 ? 10.317  -43.066 65.789  1.00 84.08  ? 139 CYS F SG  1 
ATOM   7791 N  N   . ASP F 1 140 ? 9.223   -42.141 69.847  1.00 83.98  ? 140 ASP F N   1 
ATOM   7792 C  CA  . ASP F 1 140 ? 10.012  -41.345 70.788  1.00 86.94  ? 140 ASP F CA  1 
ATOM   7793 C  C   . ASP F 1 140 ? 9.917   -41.798 72.241  1.00 80.63  ? 140 ASP F C   1 
ATOM   7794 O  O   . ASP F 1 140 ? 10.573  -41.196 73.097  1.00 83.42  ? 140 ASP F O   1 
ATOM   7795 C  CB  . ASP F 1 140 ? 9.644   -39.859 70.700  1.00 89.03  ? 140 ASP F CB  1 
ATOM   7796 C  CG  . ASP F 1 140 ? 9.700   -39.336 69.288  1.00 91.49  ? 140 ASP F CG  1 
ATOM   7797 O  OD1 . ASP F 1 140 ? 10.345  -39.998 68.454  1.00 94.85  ? 140 ASP F OD1 1 
ATOM   7798 O  OD2 . ASP F 1 140 ? 9.152   -38.246 69.021  1.00 87.60  ? 140 ASP F OD2 1 
ATOM   7799 N  N   . SER F 1 141 ? 9.121   -42.816 72.554  1.00 76.63  ? 141 SER F N   1 
ATOM   7800 C  CA  A SER F 1 141 ? 9.205   -43.425 73.871  0.86 70.45  ? 141 SER F CA  1 
ATOM   7801 C  CA  B SER F 1 141 ? 9.185   -43.446 73.868  0.14 70.87  ? 141 SER F CA  1 
ATOM   7802 C  C   . SER F 1 141 ? 10.116  -44.649 73.879  1.00 66.17  ? 141 SER F C   1 
ATOM   7803 O  O   . SER F 1 141 ? 10.771  -44.915 74.895  1.00 58.53  ? 141 SER F O   1 
ATOM   7804 C  CB  A SER F 1 141 ? 7.807   -43.788 74.368  0.86 71.10  ? 141 SER F CB  1 
ATOM   7805 C  CB  B SER F 1 141 ? 7.792   -43.881 74.331  0.14 71.35  ? 141 SER F CB  1 
ATOM   7806 O  OG  A SER F 1 141 ? 7.873   -44.657 75.472  0.86 67.37  ? 141 SER F OG  1 
ATOM   7807 O  OG  B SER F 1 141 ? 6.962   -42.763 74.592  0.14 77.01  ? 141 SER F OG  1 
ATOM   7808 N  N   . ILE F 1 142 ? 10.196  -45.383 72.764  1.00 66.39  ? 142 ILE F N   1 
ATOM   7809 C  CA  . ILE F 1 142 ? 11.128  -46.503 72.673  1.00 65.71  ? 142 ILE F CA  1 
ATOM   7810 C  C   . ILE F 1 142 ? 12.551  -45.993 72.460  1.00 60.97  ? 142 ILE F C   1 
ATOM   7811 O  O   . ILE F 1 142 ? 13.505  -46.502 73.062  1.00 46.57  ? 142 ILE F O   1 
ATOM   7812 C  CB  . ILE F 1 142 ? 10.698  -47.481 71.561  1.00 58.72  ? 142 ILE F CB  1 
ATOM   7813 C  CG1 . ILE F 1 142 ? 9.505   -48.326 72.018  1.00 59.36  ? 142 ILE F CG1 1 
ATOM   7814 C  CG2 . ILE F 1 142 ? 11.849  -48.388 71.176  1.00 56.68  ? 142 ILE F CG2 1 
ATOM   7815 C  CD1 . ILE F 1 142 ? 9.244   -49.540 71.148  1.00 64.24  ? 142 ILE F CD1 1 
ATOM   7816 N  N   . LYS F 1 143 ? 12.712  -44.971 71.617  1.00 61.74  ? 143 LYS F N   1 
ATOM   7817 C  CA  . LYS F 1 143 ? 14.026  -44.371 71.443  1.00 57.52  ? 143 LYS F CA  1 
ATOM   7818 C  C   . LYS F 1 143 ? 14.504  -43.740 72.743  1.00 54.52  ? 143 LYS F C   1 
ATOM   7819 O  O   . LYS F 1 143 ? 15.696  -43.805 73.075  1.00 51.75  ? 143 LYS F O   1 
ATOM   7820 C  CB  . LYS F 1 143 ? 13.988  -43.337 70.312  1.00 68.78  ? 143 LYS F CB  1 
ATOM   7821 C  CG  . LYS F 1 143 ? 15.369  -42.985 69.718  1.00 70.16  ? 143 LYS F CG  1 
ATOM   7822 C  CD  . LYS F 1 143 ? 15.731  -41.535 70.007  1.00 57.01  ? 143 LYS F CD  1 
ATOM   7823 C  CE  . LYS F 1 143 ? 17.092  -41.169 69.425  1.00 59.05  ? 143 LYS F CE  1 
ATOM   7824 N  NZ  . LYS F 1 143 ? 17.102  -41.096 67.940  1.00 58.29  ? 143 LYS F NZ  1 
ATOM   7825 N  N   . LYS F 1 144 ? 13.583  -43.142 73.502  1.00 55.00  ? 144 LYS F N   1 
ATOM   7826 C  CA  . LYS F 1 144 ? 13.948  -42.491 74.757  1.00 50.95  ? 144 LYS F CA  1 
ATOM   7827 C  C   . LYS F 1 144 ? 14.575  -43.488 75.728  1.00 49.89  ? 144 LYS F C   1 
ATOM   7828 O  O   . LYS F 1 144 ? 15.658  -43.235 76.272  1.00 47.47  ? 144 LYS F O   1 
ATOM   7829 C  CB  . LYS F 1 144 ? 12.714  -41.821 75.367  1.00 56.14  ? 144 LYS F CB  1 
ATOM   7830 C  CG  . LYS F 1 144 ? 12.992  -40.799 76.467  1.00 60.37  ? 144 LYS F CG  1 
ATOM   7831 C  CD  . LYS F 1 144 ? 11.694  -40.139 76.970  1.00 59.57  ? 144 LYS F CD  1 
ATOM   7832 C  CE  . LYS F 1 144 ? 10.668  -41.188 77.448  1.00 61.09  ? 144 LYS F CE  1 
ATOM   7833 N  NZ  . LYS F 1 144 ? 9.656   -40.627 78.403  1.00 65.25  ? 144 LYS F NZ  1 
ATOM   7834 N  N   . ILE F 1 145 ? 13.913  -44.639 75.946  1.00 44.92  ? 145 ILE F N   1 
ATOM   7835 C  CA  . ILE F 1 145 ? 14.507  -45.706 76.755  1.00 42.46  ? 145 ILE F CA  1 
ATOM   7836 C  C   . ILE F 1 145 ? 15.808  -46.179 76.120  1.00 42.37  ? 145 ILE F C   1 
ATOM   7837 O  O   . ILE F 1 145 ? 16.827  -46.352 76.801  1.00 37.54  ? 145 ILE F O   1 
ATOM   7838 C  CB  . ILE F 1 145 ? 13.524  -46.883 76.933  1.00 44.19  ? 145 ILE F CB  1 
ATOM   7839 C  CG1 . ILE F 1 145 ? 12.180  -46.428 77.495  1.00 41.38  ? 145 ILE F CG1 1 
ATOM   7840 C  CG2 . ILE F 1 145 ? 14.125  -47.955 77.837  1.00 35.86  ? 145 ILE F CG2 1 
ATOM   7841 C  CD1 . ILE F 1 145 ? 12.297  -45.769 78.820  1.00 46.50  ? 145 ILE F CD1 1 
ATOM   7842 N  N   . GLY F 1 146 ? 15.780  -46.411 74.802  1.00 40.46  ? 146 GLY F N   1 
ATOM   7843 C  CA  . GLY F 1 146 ? 16.987  -46.796 74.090  1.00 38.91  ? 146 GLY F CA  1 
ATOM   7844 C  C   . GLY F 1 146 ? 18.157  -45.884 74.392  1.00 41.81  ? 146 GLY F C   1 
ATOM   7845 O  O   . GLY F 1 146 ? 19.255  -46.351 74.696  1.00 41.83  ? 146 GLY F O   1 
ATOM   7846 N  N   . CYS F 1 147 ? 17.923  -44.564 74.351  1.00 40.72  ? 147 CYS F N   1 
ATOM   7847 C  CA  . CYS F 1 147 ? 18.975  -43.591 74.650  1.00 39.13  ? 147 CYS F CA  1 
ATOM   7848 C  C   . CYS F 1 147 ? 19.434  -43.663 76.092  1.00 39.35  ? 147 CYS F C   1 
ATOM   7849 O  O   . CYS F 1 147 ? 20.635  -43.560 76.370  1.00 36.07  ? 147 CYS F O   1 
ATOM   7850 C  CB  . CYS F 1 147 ? 18.502  -42.171 74.368  1.00 40.63  ? 147 CYS F CB  1 
ATOM   7851 S  SG  . CYS F 1 147 ? 19.048  -41.572 72.794  1.00 57.27  ? 147 CYS F SG  1 
ATOM   7852 N  N   . MET F 1 148 ? 18.491  -43.769 77.024  1.00 39.72  ? 148 MET F N   1 
ATOM   7853 C  CA  . MET F 1 148 ? 18.872  -43.837 78.424  1.00 39.83  ? 148 MET F CA  1 
ATOM   7854 C  C   . MET F 1 148 ? 19.770  -45.036 78.670  1.00 41.69  ? 148 MET F C   1 
ATOM   7855 O  O   . MET F 1 148 ? 20.753  -44.939 79.416  1.00 38.80  ? 148 MET F O   1 
ATOM   7856 C  CB  . MET F 1 148 ? 17.631  -43.897 79.311  1.00 36.36  ? 148 MET F CB  1 
ATOM   7857 C  CG  . MET F 1 148 ? 16.745  -42.700 79.176  1.00 36.09  ? 148 MET F CG  1 
ATOM   7858 S  SD  . MET F 1 148 ? 15.131  -42.928 79.953  1.00 42.21  ? 148 MET F SD  1 
ATOM   7859 C  CE  . MET F 1 148 ? 15.578  -42.911 81.674  1.00 37.27  ? 148 MET F CE  1 
ATOM   7860 N  N   . ILE F 1 149 ? 19.461  -46.164 78.022  1.00 36.56  ? 149 ILE F N   1 
ATOM   7861 C  CA  . ILE F 1 149 ? 20.283  -47.360 78.166  1.00 36.88  ? 149 ILE F CA  1 
ATOM   7862 C  C   . ILE F 1 149 ? 21.686  -47.086 77.657  1.00 40.94  ? 149 ILE F C   1 
ATOM   7863 O  O   . ILE F 1 149 ? 22.685  -47.374 78.332  1.00 43.15  ? 149 ILE F O   1 
ATOM   7864 C  CB  . ILE F 1 149 ? 19.639  -48.550 77.431  1.00 41.89  ? 149 ILE F CB  1 
ATOM   7865 C  CG1 . ILE F 1 149 ? 18.371  -49.004 78.175  1.00 45.25  ? 149 ILE F CG1 1 
ATOM   7866 C  CG2 . ILE F 1 149 ? 20.647  -49.691 77.263  1.00 31.37  ? 149 ILE F CG2 1 
ATOM   7867 C  CD1 . ILE F 1 149 ? 17.526  -50.033 77.427  1.00 42.59  ? 149 ILE F CD1 1 
ATOM   7868 N  N   . THR F 1 150 ? 21.780  -46.511 76.458  1.00 42.10  ? 150 THR F N   1 
ATOM   7869 C  CA  . THR F 1 150 ? 23.080  -46.204 75.880  1.00 40.77  ? 150 THR F CA  1 
ATOM   7870 C  C   . THR F 1 150 ? 23.859  -45.249 76.774  1.00 41.96  ? 150 THR F C   1 
ATOM   7871 O  O   . THR F 1 150 ? 25.043  -45.470 77.058  1.00 40.65  ? 150 THR F O   1 
ATOM   7872 C  CB  . THR F 1 150 ? 22.890  -45.607 74.491  1.00 41.68  ? 150 THR F CB  1 
ATOM   7873 O  OG1 . THR F 1 150 ? 22.417  -46.629 73.614  1.00 40.84  ? 150 THR F OG1 1 
ATOM   7874 C  CG2 . THR F 1 150 ? 24.217  -45.050 73.971  1.00 36.62  ? 150 THR F CG2 1 
ATOM   7875 N  N   . LYS F 1 151 ? 23.193  -44.189 77.251  1.00 38.67  ? 151 LYS F N   1 
ATOM   7876 C  CA  . LYS F 1 151 ? 23.868  -43.203 78.089  1.00 37.97  ? 151 LYS F CA  1 
ATOM   7877 C  C   . LYS F 1 151 ? 24.338  -43.817 79.403  1.00 44.75  ? 151 LYS F C   1 
ATOM   7878 O  O   . LYS F 1 151 ? 25.483  -43.598 79.826  1.00 41.34  ? 151 LYS F O   1 
ATOM   7879 C  CB  . LYS F 1 151 ? 22.947  -42.014 78.344  1.00 39.83  ? 151 LYS F CB  1 
ATOM   7880 C  CG  . LYS F 1 151 ? 23.565  -40.970 79.272  1.00 54.18  ? 151 LYS F CG  1 
ATOM   7881 C  CD  . LYS F 1 151 ? 22.546  -39.907 79.706  1.00 45.20  ? 151 LYS F CD  1 
ATOM   7882 C  CE  . LYS F 1 151 ? 23.180  -38.923 80.676  1.00 40.78  ? 151 LYS F CE  1 
ATOM   7883 N  NZ  . LYS F 1 151 ? 22.197  -37.906 81.139  1.00 56.29  ? 151 LYS F NZ  1 
ATOM   7884 N  N   . LEU F 1 152 ? 23.478  -44.610 80.051  1.00 41.06  ? 152 LEU F N   1 
ATOM   7885 C  CA  . LEU F 1 152 ? 23.863  -45.232 81.307  1.00 39.33  ? 152 LEU F CA  1 
ATOM   7886 C  C   . LEU F 1 152 ? 24.999  -46.225 81.108  1.00 42.43  ? 152 LEU F C   1 
ATOM   7887 O  O   . LEU F 1 152 ? 25.860  -46.363 81.985  1.00 37.95  ? 152 LEU F O   1 
ATOM   7888 C  CB  . LEU F 1 152 ? 22.650  -45.902 81.946  1.00 42.42  ? 152 LEU F CB  1 
ATOM   7889 C  CG  . LEU F 1 152 ? 22.817  -46.558 83.310  1.00 41.42  ? 152 LEU F CG  1 
ATOM   7890 C  CD1 . LEU F 1 152 ? 23.337  -45.561 84.333  1.00 41.67  ? 152 LEU F CD1 1 
ATOM   7891 C  CD2 . LEU F 1 152 ? 21.486  -47.130 83.745  1.00 44.72  ? 152 LEU F CD2 1 
ATOM   7892 N  N   . LYS F 1 153 ? 25.044  -46.911 79.962  1.00 44.17  ? 153 LYS F N   1 
ATOM   7893 C  CA  . LYS F 1 153 ? 26.212  -47.749 79.693  1.00 43.64  ? 153 LYS F CA  1 
ATOM   7894 C  C   . LYS F 1 153 ? 27.466  -46.899 79.543  1.00 41.97  ? 153 LYS F C   1 
ATOM   7895 O  O   . LYS F 1 153 ? 28.545  -47.285 80.012  1.00 41.83  ? 153 LYS F O   1 
ATOM   7896 C  CB  . LYS F 1 153 ? 25.992  -48.605 78.450  1.00 38.16  ? 153 LYS F CB  1 
ATOM   7897 C  CG  . LYS F 1 153 ? 25.150  -49.849 78.677  1.00 35.89  ? 153 LYS F CG  1 
ATOM   7898 C  CD  . LYS F 1 153 ? 24.835  -50.526 77.347  1.00 35.33  ? 153 LYS F CD  1 
ATOM   7899 C  CE  . LYS F 1 153 ? 24.048  -51.801 77.558  1.00 43.35  ? 153 LYS F CE  1 
ATOM   7900 N  NZ  . LYS F 1 153 ? 23.591  -52.345 76.256  1.00 53.58  ? 153 LYS F NZ  1 
ATOM   7901 N  N   . ARG F 1 154 ? 27.347  -45.722 78.921  1.00 45.63  ? 154 ARG F N   1 
ATOM   7902 C  CA  . ARG F 1 154 ? 28.532  -44.883 78.737  1.00 47.87  ? 154 ARG F CA  1 
ATOM   7903 C  C   . ARG F 1 154 ? 29.001  -44.296 80.063  1.00 47.13  ? 154 ARG F C   1 
ATOM   7904 O  O   . ARG F 1 154 ? 30.192  -44.353 80.386  1.00 45.34  ? 154 ARG F O   1 
ATOM   7905 C  CB  . ARG F 1 154 ? 28.268  -43.763 77.725  1.00 39.20  ? 154 ARG F CB  1 
ATOM   7906 C  CG  . ARG F 1 154 ? 29.368  -42.686 77.742  1.00 43.99  ? 154 ARG F CG  1 
ATOM   7907 C  CD  . ARG F 1 154 ? 29.070  -41.508 76.824  1.00 44.95  ? 154 ARG F CD  1 
ATOM   7908 N  NE  . ARG F 1 154 ? 28.968  -41.958 75.442  1.00 48.95  ? 154 ARG F NE  1 
ATOM   7909 C  CZ  . ARG F 1 154 ? 27.822  -42.084 74.788  1.00 47.77  ? 154 ARG F CZ  1 
ATOM   7910 N  NH1 . ARG F 1 154 ? 26.660  -41.771 75.388  1.00 43.42  ? 154 ARG F NH1 1 
ATOM   7911 N  NH2 . ARG F 1 154 ? 27.844  -42.525 73.536  1.00 43.23  ? 154 ARG F NH2 1 
ATOM   7912 N  N   . CYS F 1 155 ? 28.078  -43.732 80.850  1.00 44.22  ? 155 CYS F N   1 
ATOM   7913 C  CA  . CYS F 1 155 ? 28.424  -43.158 82.150  1.00 47.64  ? 155 CYS F CA  1 
ATOM   7914 C  C   . CYS F 1 155 ? 28.953  -44.233 83.099  1.00 48.86  ? 155 CYS F C   1 
ATOM   7915 O  O   . CYS F 1 155 ? 29.460  -43.915 84.173  1.00 47.34  ? 155 CYS F O   1 
ATOM   7916 C  CB  . CYS F 1 155 ? 27.219  -42.424 82.775  1.00 44.29  ? 155 CYS F CB  1 
ATOM   7917 S  SG  . CYS F 1 155 ? 26.573  -40.881 81.898  1.00 76.67  ? 155 CYS F SG  1 
ATOM   7918 N  N   . GLY F 1 156 ? 28.923  -45.500 82.673  1.00 59.11  ? 156 GLY F N   1 
ATOM   7919 C  CA  . GLY F 1 156 ? 29.339  -46.618 83.489  1.00 46.16  ? 156 GLY F CA  1 
ATOM   7920 C  C   . GLY F 1 156 ? 28.105  -47.027 84.243  1.00 54.56  ? 156 GLY F C   1 
ATOM   7921 O  O   . GLY F 1 156 ? 27.540  -46.234 85.001  1.00 58.92  ? 156 GLY F O   1 
ATOM   7922 N  N   . PRO F 1 157 ? 27.601  -48.235 83.983  1.00 54.38  ? 157 PRO F N   1 
ATOM   7923 C  CA  . PRO F 1 157 ? 26.241  -48.571 84.445  1.00 49.35  ? 157 PRO F CA  1 
ATOM   7924 C  C   . PRO F 1 157 ? 26.106  -48.638 85.950  1.00 54.96  ? 157 PRO F C   1 
ATOM   7925 O  O   . PRO F 1 157 ? 24.984  -48.519 86.452  1.00 59.76  ? 157 PRO F O   1 
ATOM   7926 C  CB  . PRO F 1 157 ? 25.966  -49.936 83.796  1.00 48.00  ? 157 PRO F CB  1 
ATOM   7927 C  CG  . PRO F 1 157 ? 26.911  -50.003 82.643  1.00 54.63  ? 157 PRO F CG  1 
ATOM   7928 C  CD  . PRO F 1 157 ? 28.145  -49.249 83.071  1.00 53.40  ? 157 PRO F CD  1 
ATOM   7929 N  N   . THR F 1 158 ? 27.201  -48.795 86.692  1.00 59.56  ? 158 THR F N   1 
ATOM   7930 C  CA  . THR F 1 158 ? 27.147  -48.847 88.147  1.00 58.44  ? 158 THR F CA  1 
ATOM   7931 C  C   . THR F 1 158 ? 28.046  -47.792 88.788  1.00 55.49  ? 158 THR F C   1 
ATOM   7932 O  O   . THR F 1 158 ? 29.025  -47.323 88.197  1.00 56.72  ? 158 THR F O   1 
ATOM   7933 C  CB  . THR F 1 158 ? 27.578  -50.205 88.652  1.00 54.84  ? 158 THR F CB  1 
ATOM   7934 O  OG1 . THR F 1 158 ? 28.932  -50.419 88.239  1.00 51.60  ? 158 THR F OG1 1 
ATOM   7935 C  CG2 . THR F 1 158 ? 26.674  -51.289 88.083  1.00 49.03  ? 158 THR F CG2 1 
ATOM   7936 N  N   . GLY F 1 159 ? 27.705  -47.436 90.015  1.00 51.63  ? 159 GLY F N   1 
ATOM   7937 C  CA  . GLY F 1 159 ? 28.576  -46.614 90.828  1.00 41.13  ? 159 GLY F CA  1 
ATOM   7938 C  C   . GLY F 1 159 ? 28.363  -45.141 90.579  1.00 45.00  ? 159 GLY F C   1 
ATOM   7939 O  O   . GLY F 1 159 ? 27.239  -44.648 90.652  1.00 48.61  ? 159 GLY F O   1 
ATOM   7940 N  N   . LEU F 1 160 ? 29.462  -44.444 90.293  1.00 46.42  ? 160 LEU F N   1 
ATOM   7941 C  CA  . LEU F 1 160 ? 29.433  -43.008 90.068  1.00 43.26  ? 160 LEU F CA  1 
ATOM   7942 C  C   . LEU F 1 160 ? 28.569  -42.647 88.865  1.00 47.41  ? 160 LEU F C   1 
ATOM   7943 O  O   . LEU F 1 160 ? 27.812  -41.669 88.905  1.00 44.92  ? 160 LEU F O   1 
ATOM   7944 C  CB  . LEU F 1 160 ? 30.861  -42.507 89.866  1.00 40.64  ? 160 LEU F CB  1 
ATOM   7945 C  CG  . LEU F 1 160 ? 30.979  -41.007 90.034  1.00 50.97  ? 160 LEU F CG  1 
ATOM   7946 C  CD1 . LEU F 1 160 ? 30.383  -40.669 91.376  1.00 55.13  ? 160 LEU F CD1 1 
ATOM   7947 C  CD2 . LEU F 1 160 ? 32.419  -40.583 89.966  1.00 48.41  ? 160 LEU F CD2 1 
ATOM   7948 N  N   . GLY F 1 161 ? 28.684  -43.410 87.776  1.00 43.68  ? 161 GLY F N   1 
ATOM   7949 C  CA  . GLY F 1 161 ? 27.887  -43.111 86.605  1.00 41.60  ? 161 GLY F CA  1 
ATOM   7950 C  C   . GLY F 1 161 ? 26.403  -43.281 86.859  1.00 45.85  ? 161 GLY F C   1 
ATOM   7951 O  O   . GLY F 1 161 ? 25.589  -42.488 86.380  1.00 46.06  ? 161 GLY F O   1 
ATOM   7952 N  N   . GLU F 1 162 ? 26.031  -44.305 87.630  1.00 47.45  ? 162 GLU F N   1 
ATOM   7953 C  CA  . GLU F 1 162 ? 24.629  -44.457 88.000  1.00 49.45  ? 162 GLU F CA  1 
ATOM   7954 C  C   . GLU F 1 162 ? 24.126  -43.242 88.771  1.00 48.45  ? 162 GLU F C   1 
ATOM   7955 O  O   . GLU F 1 162 ? 23.002  -42.784 88.550  1.00 46.87  ? 162 GLU F O   1 
ATOM   7956 C  CB  . GLU F 1 162 ? 24.434  -45.732 88.814  1.00 48.94  ? 162 GLU F CB  1 
ATOM   7957 C  CG  . GLU F 1 162 ? 22.982  -46.207 88.853  1.00 50.86  ? 162 GLU F CG  1 
ATOM   7958 C  CD  . GLU F 1 162 ? 22.827  -47.547 89.554  1.00 54.62  ? 162 GLU F CD  1 
ATOM   7959 O  OE1 . GLU F 1 162 ? 23.539  -47.796 90.559  1.00 56.67  ? 162 GLU F OE1 1 
ATOM   7960 O  OE2 . GLU F 1 162 ? 21.998  -48.358 89.092  1.00 50.80  ? 162 GLU F OE2 1 
ATOM   7961 N  N   . CYS F 1 163 ? 24.950  -42.695 89.667  1.00 47.39  ? 163 CYS F N   1 
ATOM   7962 C  CA  . CYS F 1 163 ? 24.552  -41.499 90.409  1.00 51.41  ? 163 CYS F CA  1 
ATOM   7963 C  C   . CYS F 1 163 ? 24.334  -40.309 89.479  1.00 53.34  ? 163 CYS F C   1 
ATOM   7964 O  O   . CYS F 1 163 ? 23.319  -39.609 89.579  1.00 49.12  ? 163 CYS F O   1 
ATOM   7965 C  CB  . CYS F 1 163 ? 25.605  -41.146 91.462  1.00 48.58  ? 163 CYS F CB  1 
ATOM   7966 S  SG  . CYS F 1 163 ? 25.584  -42.185 92.929  1.00 66.93  ? 163 CYS F SG  1 
ATOM   7967 N  N   . MET F 1 164 ? 25.299  -40.034 88.591  1.00 46.43  ? 164 MET F N   1 
ATOM   7968 C  CA  . MET F 1 164 ? 25.159  -38.870 87.723  1.00 48.64  ? 164 MET F CA  1 
ATOM   7969 C  C   . MET F 1 164 ? 24.025  -39.060 86.734  1.00 50.28  ? 164 MET F C   1 
ATOM   7970 O  O   . MET F 1 164 ? 23.284  -38.114 86.436  1.00 49.60  ? 164 MET F O   1 
ATOM   7971 C  CB  . MET F 1 164 ? 26.471  -38.578 86.999  1.00 51.86  ? 164 MET F CB  1 
ATOM   7972 C  CG  . MET F 1 164 ? 27.630  -38.519 87.979  1.00 63.11  ? 164 MET F CG  1 
ATOM   7973 S  SD  . MET F 1 164 ? 27.156  -37.586 89.467  1.00 86.36  ? 164 MET F SD  1 
ATOM   7974 C  CE  . MET F 1 164 ? 28.427  -38.167 90.562  1.00 65.89  ? 164 MET F CE  1 
ATOM   7975 N  N   . PHE F 1 165 ? 23.872  -40.272 86.216  1.00 43.69  ? 165 PHE F N   1 
ATOM   7976 C  CA  . PHE F 1 165 ? 22.747  -40.521 85.339  1.00 45.19  ? 165 PHE F CA  1 
ATOM   7977 C  C   . PHE F 1 165 ? 21.439  -40.222 86.060  1.00 46.52  ? 165 PHE F C   1 
ATOM   7978 O  O   . PHE F 1 165 ? 20.569  -39.532 85.528  1.00 43.30  ? 165 PHE F O   1 
ATOM   7979 C  CB  . PHE F 1 165 ? 22.793  -41.962 84.833  1.00 44.40  ? 165 PHE F CB  1 
ATOM   7980 C  CG  . PHE F 1 165 ? 21.661  -42.304 83.927  1.00 47.58  ? 165 PHE F CG  1 
ATOM   7981 C  CD1 . PHE F 1 165 ? 21.756  -42.068 82.566  1.00 41.83  ? 165 PHE F CD1 1 
ATOM   7982 C  CD2 . PHE F 1 165 ? 20.480  -42.823 84.442  1.00 42.07  ? 165 PHE F CD2 1 
ATOM   7983 C  CE1 . PHE F 1 165 ? 20.695  -42.365 81.731  1.00 47.20  ? 165 PHE F CE1 1 
ATOM   7984 C  CE2 . PHE F 1 165 ? 19.424  -43.123 83.617  1.00 43.15  ? 165 PHE F CE2 1 
ATOM   7985 C  CZ  . PHE F 1 165 ? 19.525  -42.901 82.259  1.00 40.71  ? 165 PHE F CZ  1 
ATOM   7986 N  N   . ASP F 1 166 ? 21.300  -40.699 87.295  1.00 47.43  ? 166 ASP F N   1 
ATOM   7987 C  CA  . ASP F 1 166 ? 20.075  -40.441 88.038  1.00 44.92  ? 166 ASP F CA  1 
ATOM   7988 C  C   . ASP F 1 166 ? 19.823  -38.953 88.224  1.00 51.65  ? 166 ASP F C   1 
ATOM   7989 O  O   . ASP F 1 166 ? 18.672  -38.502 88.132  1.00 51.86  ? 166 ASP F O   1 
ATOM   7990 C  CB  . ASP F 1 166 ? 20.126  -41.113 89.400  1.00 44.78  ? 166 ASP F CB  1 
ATOM   7991 C  CG  . ASP F 1 166 ? 18.837  -40.952 90.140  1.00 41.20  ? 166 ASP F CG  1 
ATOM   7992 O  OD1 . ASP F 1 166 ? 17.944  -41.807 89.952  1.00 47.05  ? 166 ASP F OD1 1 
ATOM   7993 O  OD2 . ASP F 1 166 ? 18.702  -39.961 90.873  1.00 44.18  ? 166 ASP F OD2 1 
ATOM   7994 N  N   . LYS F 1 167 ? 20.880  -38.180 88.531  1.00 50.35  ? 167 LYS F N   1 
ATOM   7995 C  CA  . LYS F 1 167 ? 20.722  -36.742 88.750  1.00 56.03  ? 167 LYS F CA  1 
ATOM   7996 C  C   . LYS F 1 167 ? 20.267  -36.031 87.479  1.00 57.74  ? 167 LYS F C   1 
ATOM   7997 O  O   . LYS F 1 167 ? 19.411  -35.138 87.528  1.00 61.07  ? 167 LYS F O   1 
ATOM   7998 C  CB  . LYS F 1 167 ? 22.027  -36.126 89.260  1.00 56.55  ? 167 LYS F CB  1 
ATOM   7999 C  CG  . LYS F 1 167 ? 21.829  -34.717 89.828  1.00 61.74  ? 167 LYS F CG  1 
ATOM   8000 C  CD  . LYS F 1 167 ? 23.113  -33.886 89.846  1.00 75.83  ? 167 LYS F CD  1 
ATOM   8001 C  CE  . LYS F 1 167 ? 22.837  -32.427 89.479  1.00 74.14  ? 167 LYS F CE  1 
ATOM   8002 N  NZ  . LYS F 1 167 ? 22.654  -32.255 87.999  1.00 77.62  ? 167 LYS F NZ  1 
ATOM   8003 N  N   . GLU F 1 168 ? 20.825  -36.418 86.330  1.00 55.56  ? 168 GLU F N   1 
ATOM   8004 C  CA  . GLU F 1 168 ? 20.469  -35.762 85.077  1.00 59.84  ? 168 GLU F CA  1 
ATOM   8005 C  C   . GLU F 1 168 ? 19.076  -36.165 84.625  1.00 57.48  ? 168 GLU F C   1 
ATOM   8006 O  O   . GLU F 1 168 ? 18.418  -35.409 83.904  1.00 55.64  ? 168 GLU F O   1 
ATOM   8007 C  CB  . GLU F 1 168 ? 21.524  -36.080 84.015  1.00 51.38  ? 168 GLU F CB  1 
ATOM   8008 C  CG  . GLU F 1 168 ? 22.897  -35.539 84.428  1.00 64.36  ? 168 GLU F CG  1 
ATOM   8009 C  CD  . GLU F 1 168 ? 23.936  -35.547 83.312  1.00 73.86  ? 168 GLU F CD  1 
ATOM   8010 O  OE1 . GLU F 1 168 ? 25.150  -35.523 83.647  1.00 66.10  ? 168 GLU F OE1 1 
ATOM   8011 O  OE2 . GLU F 1 168 ? 23.547  -35.577 82.116  1.00 66.45  ? 168 GLU F OE2 1 
ATOM   8012 N  N   . LEU F 1 169 ? 18.623  -37.348 85.043  1.00 54.95  ? 169 LEU F N   1 
ATOM   8013 C  CA  . LEU F 1 169 ? 17.233  -37.748 84.857  1.00 58.80  ? 169 LEU F CA  1 
ATOM   8014 C  C   . LEU F 1 169 ? 16.297  -36.779 85.559  1.00 69.33  ? 169 LEU F C   1 
ATOM   8015 O  O   . LEU F 1 169 ? 15.299  -36.318 84.989  1.00 63.62  ? 169 LEU F O   1 
ATOM   8016 C  CB  . LEU F 1 169 ? 17.030  -39.144 85.435  1.00 49.91  ? 169 LEU F CB  1 
ATOM   8017 C  CG  . LEU F 1 169 ? 16.271  -40.163 84.631  1.00 51.95  ? 169 LEU F CG  1 
ATOM   8018 C  CD1 . LEU F 1 169 ? 16.897  -40.187 83.266  1.00 56.73  ? 169 LEU F CD1 1 
ATOM   8019 C  CD2 . LEU F 1 169 ? 16.402  -41.497 85.330  1.00 52.82  ? 169 LEU F CD2 1 
ATOM   8020 N  N   . ASN F 1 170 ? 16.619  -36.477 86.814  1.00 75.16  ? 170 ASN F N   1 
ATOM   8021 C  CA  . ASN F 1 170 ? 15.793  -35.709 87.724  1.00 74.48  ? 170 ASN F CA  1 
ATOM   8022 C  C   . ASN F 1 170 ? 15.806  -34.208 87.383  1.00 81.74  ? 170 ASN F C   1 
ATOM   8023 O  O   . ASN F 1 170 ? 16.777  -33.676 86.804  1.00 75.58  ? 170 ASN F O   1 
ATOM   8024 C  CB  . ASN F 1 170 ? 16.277  -35.952 89.158  1.00 56.77  ? 170 ASN F CB  1 
ATOM   8025 C  CG  . ASN F 1 170 ? 15.148  -35.884 90.167  1.00 74.76  ? 170 ASN F CG  1 
ATOM   8026 O  OD1 . ASN F 1 170 ? 14.007  -35.573 89.810  1.00 79.93  ? 170 ASN F OD1 1 
ATOM   8027 N  ND2 . ASN F 1 170 ? 15.458  -36.159 91.437  1.00 62.30  ? 170 ASN F ND2 1 
ATOM   8028 O  OXT . ASN F 1 170 ? 14.829  -33.503 87.678  1.00 79.52  ? 170 ASN F OXT 1 
HETATM 8029 FE FE  . FE  G 2 .   ? 9.432   -30.731 50.791  1.00 102.50 ? 201 FE  B FE  1 
HETATM 8030 FE FE  . FE  H 2 .   ? 7.285   -27.075 50.828  1.00 110.12 ? 202 FE  B FE  1 
HETATM 8031 FE FE  . FE  I 2 .   ? 33.522  -20.923 58.969  1.00 105.77 ? 201 FE  A FE  1 
HETATM 8032 FE FE  . FE  J 2 .   ? 16.394  -52.323 12.717  1.00 113.23 ? 201 FE  C FE  1 
HETATM 8033 FE FE  . FE  K 2 .   ? 47.752  -26.143 29.670  1.00 107.92 ? 201 FE  D FE  1 
HETATM 8034 FE FE  . FE  L 2 .   ? 47.403  -26.201 25.910  1.00 114.45 ? 202 FE  D FE  1 
HETATM 8035 FE FE  . FE  M 2 .   ? 34.311  -47.512 37.378  1.00 100.78 ? 201 FE  E FE  1 
HETATM 8036 FE FE  . FE  N 2 .   ? 36.708  -50.168 38.337  1.00 106.49 ? 202 FE  E FE  1 
HETATM 8037 FE FE  . FE  O 2 .   ? 0.890   -47.401 75.820  1.00 113.01 ? 201 FE  F FE  1 
HETATM 8038 FE FE  . FE  P 2 .   ? 4.729   -45.083 75.681  1.00 113.49 ? 202 FE  F FE  1 
HETATM 8039 O  O   . HOH Q 3 .   ? 8.204   -12.365 36.271  1.00 47.99  ? 301 HOH B O   1 
HETATM 8040 O  O   . HOH Q 3 .   ? -1.283  -9.725  32.135  1.00 31.29  ? 302 HOH B O   1 
HETATM 8041 O  O   . HOH Q 3 .   ? 12.992  -27.292 38.546  1.00 41.29  ? 303 HOH B O   1 
HETATM 8042 O  O   . HOH Q 3 .   ? 28.834  -23.853 45.989  1.00 31.77  ? 304 HOH B O   1 
HETATM 8043 O  O   . HOH Q 3 .   ? 23.950  -37.698 45.467  1.00 41.36  ? 305 HOH B O   1 
HETATM 8044 O  O   . HOH Q 3 .   ? 21.752  -34.316 44.527  1.00 37.75  ? 306 HOH B O   1 
HETATM 8045 O  O   . HOH Q 3 .   ? 22.928  -15.367 41.913  1.00 36.52  ? 307 HOH B O   1 
HETATM 8046 O  O   . HOH Q 3 .   ? -4.543  -24.793 48.525  1.00 75.60  ? 308 HOH B O   1 
HETATM 8047 O  O   . HOH Q 3 .   ? 23.537  -36.299 43.210  1.00 38.17  ? 309 HOH B O   1 
HETATM 8048 O  O   . HOH Q 3 .   ? 19.710  -34.237 42.973  1.00 37.21  ? 310 HOH B O   1 
HETATM 8049 O  O   . HOH R 3 .   ? 23.727  -10.430 37.875  1.00 65.87  ? 301 HOH A O   1 
HETATM 8050 O  O   . HOH R 3 .   ? 17.968  -37.676 65.270  1.00 39.87  ? 302 HOH A O   1 
HETATM 8051 O  O   . HOH R 3 .   ? 29.988  -21.279 45.207  1.00 33.31  ? 303 HOH A O   1 
HETATM 8052 O  O   . HOH R 3 .   ? 25.686  -35.696 41.896  1.00 35.55  ? 304 HOH A O   1 
HETATM 8053 O  O   . HOH R 3 .   ? 24.520  -38.158 60.266  1.00 31.41  ? 305 HOH A O   1 
HETATM 8054 O  O   . HOH R 3 .   ? 24.942  -13.713 41.607  1.00 43.38  ? 306 HOH A O   1 
HETATM 8055 O  O   . HOH R 3 .   ? 42.023  -38.024 81.674  1.00 31.00  ? 307 HOH A O   1 
HETATM 8056 O  O   . HOH R 3 .   ? 31.679  -21.866 41.042  1.00 31.33  ? 308 HOH A O   1 
HETATM 8057 O  O   . HOH R 3 .   ? 32.036  -29.353 48.363  1.00 31.45  ? 309 HOH A O   1 
HETATM 8058 O  O   . HOH R 3 .   ? 32.503  -3.923  42.814  1.00 47.14  ? 310 HOH A O   1 
HETATM 8059 O  O   . HOH R 3 .   ? 23.835  -40.496 61.683  1.00 36.58  ? 311 HOH A O   1 
HETATM 8060 O  O   . HOH R 3 .   ? 37.552  -21.039 74.818  1.00 53.65  ? 312 HOH A O   1 
HETATM 8061 O  O   . HOH S 3 .   ? 32.969  -39.013 1.369   1.00 54.07  ? 301 HOH C O   1 
HETATM 8062 O  O   . HOH S 3 .   ? 13.121  -75.376 14.209  1.00 45.36  ? 302 HOH C O   1 
HETATM 8063 O  O   . HOH S 3 .   ? 25.772  -25.594 15.440  1.00 47.30  ? 303 HOH C O   1 
HETATM 8064 O  O   . HOH S 3 .   ? 5.071   -55.982 9.823   1.00 44.74  ? 304 HOH C O   1 
HETATM 8065 O  O   . HOH S 3 .   ? 17.442  -32.227 2.157   1.00 46.79  ? 305 HOH C O   1 
HETATM 8066 O  O   . HOH S 3 .   ? 21.297  -24.177 7.615   1.00 41.15  ? 306 HOH C O   1 
HETATM 8067 O  O   . HOH S 3 .   ? 10.102  -72.255 10.904  1.00 41.15  ? 307 HOH C O   1 
HETATM 8068 O  O   . HOH S 3 .   ? 18.279  -71.652 13.562  1.00 49.73  ? 308 HOH C O   1 
HETATM 8069 O  O   . HOH S 3 .   ? 22.779  -24.608 1.169   1.00 44.04  ? 309 HOH C O   1 
HETATM 8070 O  O   . HOH S 3 .   ? 5.255   -53.895 9.575   1.00 54.49  ? 310 HOH C O   1 
HETATM 8071 O  O   . HOH T 3 .   ? 31.986  -15.376 6.530   1.00 36.40  ? 301 HOH D O   1 
HETATM 8072 O  O   . HOH T 3 .   ? 28.360  -38.532 23.209  1.00 47.86  ? 302 HOH D O   1 
HETATM 8073 O  O   . HOH T 3 .   ? 43.202  -29.985 20.590  1.00 44.96  ? 303 HOH D O   1 
HETATM 8074 O  O   . HOH T 3 .   ? 21.849  -35.930 23.231  1.00 51.17  ? 304 HOH D O   1 
HETATM 8075 O  O   . HOH T 3 .   ? 30.234  -34.692 36.969  1.00 30.53  ? 305 HOH D O   1 
HETATM 8076 O  O   . HOH T 3 .   ? 31.669  -22.112 31.357  1.00 40.70  ? 306 HOH D O   1 
HETATM 8077 O  O   . HOH T 3 .   ? 38.518  -25.717 40.574  1.00 35.44  ? 307 HOH D O   1 
HETATM 8078 O  O   . HOH T 3 .   ? 38.682  -23.348 38.930  1.00 32.96  ? 308 HOH D O   1 
HETATM 8079 O  O   . HOH U 3 .   ? 43.744  -62.264 41.554  1.00 79.38  ? 301 HOH E O   1 
HETATM 8080 O  O   . HOH U 3 .   ? 58.169  -58.036 55.306  1.00 47.76  ? 302 HOH E O   1 
HETATM 8081 O  O   . HOH U 3 .   ? 14.080  -44.457 31.636  1.00 62.11  ? 303 HOH E O   1 
HETATM 8082 O  O   . HOH U 3 .   ? 20.171  -33.461 32.087  1.00 49.30  ? 304 HOH E O   1 
HETATM 8083 O  O   . HOH U 3 .   ? 44.480  -37.581 30.160  1.00 52.05  ? 305 HOH E O   1 
HETATM 8084 O  O   . HOH U 3 .   ? 52.614  -62.150 56.329  1.00 40.92  ? 306 HOH E O   1 
HETATM 8085 O  O   . HOH U 3 .   ? 28.894  -28.577 40.596  1.00 29.99  ? 307 HOH E O   1 
HETATM 8086 O  O   . HOH U 3 .   ? 27.861  -35.371 36.078  1.00 32.48  ? 308 HOH E O   1 
HETATM 8087 O  O   . HOH U 3 .   ? 24.300  -33.016 37.324  1.00 32.17  ? 309 HOH E O   1 
HETATM 8088 O  O   . HOH U 3 .   ? 32.702  -35.560 43.581  1.00 36.73  ? 310 HOH E O   1 
HETATM 8089 O  O   . HOH U 3 .   ? 30.486  -57.517 41.150  1.00 78.16  ? 311 HOH E O   1 
HETATM 8090 O  O   . HOH V 3 .   ? 8.325   -44.964 98.590  1.00 41.80  ? 301 HOH F O   1 
HETATM 8091 O  O   . HOH V 3 .   ? 29.702  -48.921 86.271  1.00 46.85  ? 302 HOH F O   1 
HETATM 8092 O  O   . HOH V 3 .   ? 30.982  -46.885 80.762  1.00 32.70  ? 303 HOH F O   1 
HETATM 8093 O  O   . HOH V 3 .   ? 22.342  -49.021 86.620  1.00 47.21  ? 304 HOH F O   1 
HETATM 8094 O  O   . HOH V 3 .   ? 6.611   -55.825 91.664  1.00 45.75  ? 305 HOH F O   1 
HETATM 8095 O  O   . HOH V 3 .   ? -9.438  -54.902 79.162  1.00 46.95  ? 306 HOH F O   1 
HETATM 8096 O  O   . HOH V 3 .   ? 12.015  -59.919 91.864  1.00 42.35  ? 307 HOH F O   1 
HETATM 8097 O  O   . HOH V 3 .   ? -8.449  -55.362 81.535  1.00 38.42  ? 308 HOH F O   1 
# 
