data_8YKL
# 
_entry.id   8YKL 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8YKL         pdb_00008ykl 10.2210/pdb8ykl/pdb 
WWPDB D_1300043863 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8YKL 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-05 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              rmsl_2040@163.com 
_pdbx_contact_author.name_first         Jian 
_pdbx_contact_author.name_last          Li 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9511-4219 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhou, X.L.' 1 ? 
'Lin, C.'    2 ? 
'Zhang, J.'  3 ? 
'Li, J.'     4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Int.J.Biol.Macromol. 
_citation.journal_id_ASTM           IJBMDR 
_citation.journal_id_CSD            0708 
_citation.journal_id_ISSN           0141-8130 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            276 
_citation.language                  ? 
_citation.page_first                133706 
_citation.page_last                 133706 
_citation.title                     
'Crystal structures of coronaviral main proteases in complex with the non-covalent inhibitor X77.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.ijbiomac.2024.133706 
_citation.pdbx_database_id_PubMed   38981557 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Jiang, H.' 1 ? 
primary 'Li, W.'    2 ? 
primary 'Zhou, X.'  3 ? 
primary 'Zhang, J.' 4 ? 
primary 'Li, J.'    5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man ORF1a                                                                                                        
32720.400 2   ? C148A ? ? 
2 non-polymer syn 'N-(4-tert-butylphenyl)-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-1H-imidazole-4-carboxamide' 
459.583   2   ? ?     ? ? 
3 water       nat water                                                                                                        
18.015    187 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVV
GHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSAGSVGYTKEGSVIN
FCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQ
FTEFVGTQSVDMLAVKTGVAIEQLLYAIQQLYTGFQGKQILGSTMLEDEFTPEDVNMQIM
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVV
GHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSAGSVGYTKEGSVIN
FCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQ
FTEFVGTQSVDMLAVKTGVAIEQLLYAIQQLYTGFQGKQILGSTMLEDEFTPEDVNMQIM
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'N-(4-tert-butylphenyl)-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-1H-imidazole-4-carboxamide' X77 
3 water                                                                                                        HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   LEU n 
1 3   VAL n 
1 4   LYS n 
1 5   MET n 
1 6   SER n 
1 7   HIS n 
1 8   PRO n 
1 9   SER n 
1 10  GLY n 
1 11  ASP n 
1 12  VAL n 
1 13  GLU n 
1 14  ALA n 
1 15  CYS n 
1 16  MET n 
1 17  VAL n 
1 18  GLN n 
1 19  VAL n 
1 20  THR n 
1 21  CYS n 
1 22  GLY n 
1 23  SER n 
1 24  MET n 
1 25  THR n 
1 26  LEU n 
1 27  ASN n 
1 28  GLY n 
1 29  LEU n 
1 30  TRP n 
1 31  LEU n 
1 32  ASP n 
1 33  ASN n 
1 34  THR n 
1 35  VAL n 
1 36  TRP n 
1 37  CYS n 
1 38  PRO n 
1 39  ARG n 
1 40  HIS n 
1 41  VAL n 
1 42  MET n 
1 43  CYS n 
1 44  PRO n 
1 45  ALA n 
1 46  ASP n 
1 47  GLN n 
1 48  LEU n 
1 49  SER n 
1 50  ASP n 
1 51  PRO n 
1 52  ASN n 
1 53  TYR n 
1 54  ASP n 
1 55  ALA n 
1 56  LEU n 
1 57  LEU n 
1 58  ILE n 
1 59  SER n 
1 60  MET n 
1 61  THR n 
1 62  ASN n 
1 63  HIS n 
1 64  SER n 
1 65  PHE n 
1 66  SER n 
1 67  VAL n 
1 68  GLN n 
1 69  LYS n 
1 70  HIS n 
1 71  ILE n 
1 72  GLY n 
1 73  ALA n 
1 74  PRO n 
1 75  ALA n 
1 76  ASN n 
1 77  LEU n 
1 78  ARG n 
1 79  VAL n 
1 80  VAL n 
1 81  GLY n 
1 82  HIS n 
1 83  ALA n 
1 84  MET n 
1 85  GLN n 
1 86  GLY n 
1 87  THR n 
1 88  LEU n 
1 89  LEU n 
1 90  LYS n 
1 91  LEU n 
1 92  THR n 
1 93  VAL n 
1 94  ASP n 
1 95  VAL n 
1 96  ALA n 
1 97  ASN n 
1 98  PRO n 
1 99  SER n 
1 100 THR n 
1 101 PRO n 
1 102 ALA n 
1 103 TYR n 
1 104 THR n 
1 105 PHE n 
1 106 THR n 
1 107 THR n 
1 108 VAL n 
1 109 LYS n 
1 110 PRO n 
1 111 GLY n 
1 112 ALA n 
1 113 ALA n 
1 114 PHE n 
1 115 SER n 
1 116 VAL n 
1 117 LEU n 
1 118 ALA n 
1 119 CYS n 
1 120 TYR n 
1 121 ASN n 
1 122 GLY n 
1 123 ARG n 
1 124 PRO n 
1 125 THR n 
1 126 GLY n 
1 127 THR n 
1 128 PHE n 
1 129 THR n 
1 130 VAL n 
1 131 VAL n 
1 132 MET n 
1 133 ARG n 
1 134 PRO n 
1 135 ASN n 
1 136 TYR n 
1 137 THR n 
1 138 ILE n 
1 139 LYS n 
1 140 GLY n 
1 141 SER n 
1 142 PHE n 
1 143 LEU n 
1 144 CYS n 
1 145 GLY n 
1 146 SER n 
1 147 ALA n 
1 148 GLY n 
1 149 SER n 
1 150 VAL n 
1 151 GLY n 
1 152 TYR n 
1 153 THR n 
1 154 LYS n 
1 155 GLU n 
1 156 GLY n 
1 157 SER n 
1 158 VAL n 
1 159 ILE n 
1 160 ASN n 
1 161 PHE n 
1 162 CYS n 
1 163 TYR n 
1 164 MET n 
1 165 HIS n 
1 166 GLN n 
1 167 MET n 
1 168 GLU n 
1 169 LEU n 
1 170 ALA n 
1 171 ASN n 
1 172 GLY n 
1 173 THR n 
1 174 HIS n 
1 175 THR n 
1 176 GLY n 
1 177 SER n 
1 178 ALA n 
1 179 PHE n 
1 180 ASP n 
1 181 GLY n 
1 182 THR n 
1 183 MET n 
1 184 TYR n 
1 185 GLY n 
1 186 ALA n 
1 187 PHE n 
1 188 MET n 
1 189 ASP n 
1 190 LYS n 
1 191 GLN n 
1 192 VAL n 
1 193 HIS n 
1 194 GLN n 
1 195 VAL n 
1 196 GLN n 
1 197 LEU n 
1 198 THR n 
1 199 ASP n 
1 200 LYS n 
1 201 TYR n 
1 202 CYS n 
1 203 SER n 
1 204 VAL n 
1 205 ASN n 
1 206 VAL n 
1 207 VAL n 
1 208 ALA n 
1 209 TRP n 
1 210 LEU n 
1 211 TYR n 
1 212 ALA n 
1 213 ALA n 
1 214 ILE n 
1 215 LEU n 
1 216 ASN n 
1 217 GLY n 
1 218 CYS n 
1 219 ALA n 
1 220 TRP n 
1 221 PHE n 
1 222 VAL n 
1 223 LYS n 
1 224 PRO n 
1 225 ASN n 
1 226 ARG n 
1 227 THR n 
1 228 SER n 
1 229 VAL n 
1 230 VAL n 
1 231 SER n 
1 232 PHE n 
1 233 ASN n 
1 234 GLU n 
1 235 TRP n 
1 236 ALA n 
1 237 LEU n 
1 238 ALA n 
1 239 ASN n 
1 240 GLN n 
1 241 PHE n 
1 242 THR n 
1 243 GLU n 
1 244 PHE n 
1 245 VAL n 
1 246 GLY n 
1 247 THR n 
1 248 GLN n 
1 249 SER n 
1 250 VAL n 
1 251 ASP n 
1 252 MET n 
1 253 LEU n 
1 254 ALA n 
1 255 VAL n 
1 256 LYS n 
1 257 THR n 
1 258 GLY n 
1 259 VAL n 
1 260 ALA n 
1 261 ILE n 
1 262 GLU n 
1 263 GLN n 
1 264 LEU n 
1 265 LEU n 
1 266 TYR n 
1 267 ALA n 
1 268 ILE n 
1 269 GLN n 
1 270 GLN n 
1 271 LEU n 
1 272 TYR n 
1 273 THR n 
1 274 GLY n 
1 275 PHE n 
1 276 GLN n 
1 277 GLY n 
1 278 LYS n 
1 279 GLN n 
1 280 ILE n 
1 281 LEU n 
1 282 GLY n 
1 283 SER n 
1 284 THR n 
1 285 MET n 
1 286 LEU n 
1 287 GLU n 
1 288 ASP n 
1 289 GLU n 
1 290 PHE n 
1 291 THR n 
1 292 PRO n 
1 293 GLU n 
1 294 ASP n 
1 295 VAL n 
1 296 ASN n 
1 297 MET n 
1 298 GLN n 
1 299 ILE n 
1 300 MET n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   300 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Middle East respiratory syndrome-related coronavirus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1335626 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     511693 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               BL21 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2'    117.146 
X77 non-polymer         . 
'N-(4-tert-butylphenyl)-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-1H-imidazole-4-carboxamide' ? 'C27 H33 N5 O2'  
459.583 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   2   ?   ?   ?   A . n 
A 1 2   LEU 2   3   3   LEU LEU A . n 
A 1 3   VAL 3   4   4   VAL VAL A . n 
A 1 4   LYS 4   5   5   LYS LYS A . n 
A 1 5   MET 5   6   6   MET MET A . n 
A 1 6   SER 6   7   7   SER SER A . n 
A 1 7   HIS 7   8   8   HIS HIS A . n 
A 1 8   PRO 8   9   9   PRO PRO A . n 
A 1 9   SER 9   10  10  SER SER A . n 
A 1 10  GLY 10  11  11  GLY GLY A . n 
A 1 11  ASP 11  12  12  ASP ASP A . n 
A 1 12  VAL 12  13  13  VAL VAL A . n 
A 1 13  GLU 13  14  14  GLU GLU A . n 
A 1 14  ALA 14  15  15  ALA ALA A . n 
A 1 15  CYS 15  16  16  CYS CYS A . n 
A 1 16  MET 16  17  17  MET MET A . n 
A 1 17  VAL 17  18  18  VAL VAL A . n 
A 1 18  GLN 18  19  19  GLN GLN A . n 
A 1 19  VAL 19  20  20  VAL VAL A . n 
A 1 20  THR 20  21  21  THR THR A . n 
A 1 21  CYS 21  22  22  CYS CYS A . n 
A 1 22  GLY 22  23  23  GLY GLY A . n 
A 1 23  SER 23  24  24  SER SER A . n 
A 1 24  MET 24  25  25  MET MET A . n 
A 1 25  THR 25  26  26  THR THR A . n 
A 1 26  LEU 26  27  27  LEU LEU A . n 
A 1 27  ASN 27  28  28  ASN ASN A . n 
A 1 28  GLY 28  29  29  GLY GLY A . n 
A 1 29  LEU 29  30  30  LEU LEU A . n 
A 1 30  TRP 30  31  31  TRP TRP A . n 
A 1 31  LEU 31  32  32  LEU LEU A . n 
A 1 32  ASP 32  33  33  ASP ASP A . n 
A 1 33  ASN 33  34  34  ASN ASN A . n 
A 1 34  THR 34  35  35  THR THR A . n 
A 1 35  VAL 35  36  36  VAL VAL A . n 
A 1 36  TRP 36  37  37  TRP TRP A . n 
A 1 37  CYS 37  38  38  CYS CYS A . n 
A 1 38  PRO 38  39  39  PRO PRO A . n 
A 1 39  ARG 39  40  40  ARG ARG A . n 
A 1 40  HIS 40  41  41  HIS HIS A . n 
A 1 41  VAL 41  42  42  VAL VAL A . n 
A 1 42  MET 42  43  43  MET MET A . n 
A 1 43  CYS 43  44  44  CYS CYS A . n 
A 1 44  PRO 44  45  45  PRO PRO A . n 
A 1 45  ALA 45  46  46  ALA ALA A . n 
A 1 46  ASP 46  47  47  ASP ASP A . n 
A 1 47  GLN 47  48  48  GLN GLN A . n 
A 1 48  LEU 48  49  49  LEU LEU A . n 
A 1 49  SER 49  50  50  SER SER A . n 
A 1 50  ASP 50  51  51  ASP ASP A . n 
A 1 51  PRO 51  52  52  PRO PRO A . n 
A 1 52  ASN 52  53  53  ASN ASN A . n 
A 1 53  TYR 53  54  54  TYR TYR A . n 
A 1 54  ASP 54  55  55  ASP ASP A . n 
A 1 55  ALA 55  56  56  ALA ALA A . n 
A 1 56  LEU 56  57  57  LEU LEU A . n 
A 1 57  LEU 57  58  58  LEU LEU A . n 
A 1 58  ILE 58  59  59  ILE ILE A . n 
A 1 59  SER 59  60  60  SER SER A . n 
A 1 60  MET 60  61  61  MET MET A . n 
A 1 61  THR 61  62  62  THR THR A . n 
A 1 62  ASN 62  63  63  ASN ASN A . n 
A 1 63  HIS 63  64  64  HIS HIS A . n 
A 1 64  SER 64  65  65  SER SER A . n 
A 1 65  PHE 65  66  66  PHE PHE A . n 
A 1 66  SER 66  67  67  SER SER A . n 
A 1 67  VAL 67  68  68  VAL VAL A . n 
A 1 68  GLN 68  69  69  GLN GLN A . n 
A 1 69  LYS 69  70  70  LYS LYS A . n 
A 1 70  HIS 70  71  71  HIS HIS A . n 
A 1 71  ILE 71  72  72  ILE ILE A . n 
A 1 72  GLY 72  73  73  GLY GLY A . n 
A 1 73  ALA 73  74  74  ALA ALA A . n 
A 1 74  PRO 74  75  75  PRO PRO A . n 
A 1 75  ALA 75  76  76  ALA ALA A . n 
A 1 76  ASN 76  77  77  ASN ASN A . n 
A 1 77  LEU 77  78  78  LEU LEU A . n 
A 1 78  ARG 78  79  79  ARG ARG A . n 
A 1 79  VAL 79  80  80  VAL VAL A . n 
A 1 80  VAL 80  81  81  VAL VAL A . n 
A 1 81  GLY 81  82  82  GLY GLY A . n 
A 1 82  HIS 82  83  83  HIS HIS A . n 
A 1 83  ALA 83  84  84  ALA ALA A . n 
A 1 84  MET 84  85  85  MET MET A . n 
A 1 85  GLN 85  86  86  GLN GLN A . n 
A 1 86  GLY 86  87  87  GLY GLY A . n 
A 1 87  THR 87  88  88  THR THR A . n 
A 1 88  LEU 88  89  89  LEU LEU A . n 
A 1 89  LEU 89  90  90  LEU LEU A . n 
A 1 90  LYS 90  91  91  LYS LYS A . n 
A 1 91  LEU 91  92  92  LEU LEU A . n 
A 1 92  THR 92  93  93  THR THR A . n 
A 1 93  VAL 93  94  94  VAL VAL A . n 
A 1 94  ASP 94  95  95  ASP ASP A . n 
A 1 95  VAL 95  96  96  VAL VAL A . n 
A 1 96  ALA 96  97  97  ALA ALA A . n 
A 1 97  ASN 97  98  98  ASN ASN A . n 
A 1 98  PRO 98  99  99  PRO PRO A . n 
A 1 99  SER 99  100 100 SER SER A . n 
A 1 100 THR 100 101 101 THR THR A . n 
A 1 101 PRO 101 102 102 PRO PRO A . n 
A 1 102 ALA 102 103 103 ALA ALA A . n 
A 1 103 TYR 103 104 104 TYR TYR A . n 
A 1 104 THR 104 105 105 THR THR A . n 
A 1 105 PHE 105 106 106 PHE PHE A . n 
A 1 106 THR 106 107 107 THR THR A . n 
A 1 107 THR 107 108 108 THR THR A . n 
A 1 108 VAL 108 109 109 VAL VAL A . n 
A 1 109 LYS 109 110 110 LYS LYS A . n 
A 1 110 PRO 110 111 111 PRO PRO A . n 
A 1 111 GLY 111 112 112 GLY GLY A . n 
A 1 112 ALA 112 113 113 ALA ALA A . n 
A 1 113 ALA 113 114 114 ALA ALA A . n 
A 1 114 PHE 114 115 115 PHE PHE A . n 
A 1 115 SER 115 116 116 SER SER A . n 
A 1 116 VAL 116 117 117 VAL VAL A . n 
A 1 117 LEU 117 118 118 LEU LEU A . n 
A 1 118 ALA 118 119 119 ALA ALA A . n 
A 1 119 CYS 119 120 120 CYS CYS A . n 
A 1 120 TYR 120 121 121 TYR TYR A . n 
A 1 121 ASN 121 122 122 ASN ASN A . n 
A 1 122 GLY 122 123 123 GLY GLY A . n 
A 1 123 ARG 123 124 124 ARG ARG A . n 
A 1 124 PRO 124 125 125 PRO PRO A . n 
A 1 125 THR 125 126 126 THR THR A . n 
A 1 126 GLY 126 127 127 GLY GLY A . n 
A 1 127 THR 127 128 128 THR THR A . n 
A 1 128 PHE 128 129 129 PHE PHE A . n 
A 1 129 THR 129 130 130 THR THR A . n 
A 1 130 VAL 130 131 131 VAL VAL A . n 
A 1 131 VAL 131 132 132 VAL VAL A . n 
A 1 132 MET 132 133 133 MET MET A . n 
A 1 133 ARG 133 134 134 ARG ARG A . n 
A 1 134 PRO 134 135 135 PRO PRO A . n 
A 1 135 ASN 135 136 136 ASN ASN A . n 
A 1 136 TYR 136 137 137 TYR TYR A . n 
A 1 137 THR 137 138 138 THR THR A . n 
A 1 138 ILE 138 139 139 ILE ILE A . n 
A 1 139 LYS 139 140 140 LYS LYS A . n 
A 1 140 GLY 140 141 141 GLY GLY A . n 
A 1 141 SER 141 142 142 SER SER A . n 
A 1 142 PHE 142 143 143 PHE PHE A . n 
A 1 143 LEU 143 144 144 LEU LEU A . n 
A 1 144 CYS 144 145 145 CYS CYS A . n 
A 1 145 GLY 145 146 146 GLY GLY A . n 
A 1 146 SER 146 147 147 SER SER A . n 
A 1 147 ALA 147 148 148 ALA ALA A . n 
A 1 148 GLY 148 149 149 GLY GLY A . n 
A 1 149 SER 149 150 150 SER SER A . n 
A 1 150 VAL 150 151 151 VAL VAL A . n 
A 1 151 GLY 151 152 152 GLY GLY A . n 
A 1 152 TYR 152 153 153 TYR TYR A . n 
A 1 153 THR 153 154 154 THR THR A . n 
A 1 154 LYS 154 155 155 LYS LYS A . n 
A 1 155 GLU 155 156 156 GLU GLU A . n 
A 1 156 GLY 156 157 157 GLY GLY A . n 
A 1 157 SER 157 158 158 SER SER A . n 
A 1 158 VAL 158 159 159 VAL VAL A . n 
A 1 159 ILE 159 160 160 ILE ILE A . n 
A 1 160 ASN 160 161 161 ASN ASN A . n 
A 1 161 PHE 161 162 162 PHE PHE A . n 
A 1 162 CYS 162 163 163 CYS CYS A . n 
A 1 163 TYR 163 164 164 TYR TYR A . n 
A 1 164 MET 164 165 165 MET MET A . n 
A 1 165 HIS 165 166 166 HIS HIS A . n 
A 1 166 GLN 166 167 167 GLN GLN A . n 
A 1 167 MET 167 168 168 MET MET A . n 
A 1 168 GLU 168 169 169 GLU GLU A . n 
A 1 169 LEU 169 170 170 LEU LEU A . n 
A 1 170 ALA 170 171 171 ALA ALA A . n 
A 1 171 ASN 171 172 172 ASN ASN A . n 
A 1 172 GLY 172 173 173 GLY GLY A . n 
A 1 173 THR 173 174 174 THR THR A . n 
A 1 174 HIS 174 175 175 HIS HIS A . n 
A 1 175 THR 175 176 176 THR THR A . n 
A 1 176 GLY 176 177 177 GLY GLY A . n 
A 1 177 SER 177 178 178 SER SER A . n 
A 1 178 ALA 178 179 179 ALA ALA A . n 
A 1 179 PHE 179 180 180 PHE PHE A . n 
A 1 180 ASP 180 181 181 ASP ASP A . n 
A 1 181 GLY 181 182 182 GLY GLY A . n 
A 1 182 THR 182 183 183 THR THR A . n 
A 1 183 MET 183 184 184 MET MET A . n 
A 1 184 TYR 184 185 185 TYR TYR A . n 
A 1 185 GLY 185 186 186 GLY GLY A . n 
A 1 186 ALA 186 187 187 ALA ALA A . n 
A 1 187 PHE 187 188 188 PHE PHE A . n 
A 1 188 MET 188 189 189 MET MET A . n 
A 1 189 ASP 189 190 190 ASP ASP A . n 
A 1 190 LYS 190 191 191 LYS LYS A . n 
A 1 191 GLN 191 192 192 GLN GLN A . n 
A 1 192 VAL 192 193 193 VAL VAL A . n 
A 1 193 HIS 193 194 194 HIS HIS A . n 
A 1 194 GLN 194 195 195 GLN GLN A . n 
A 1 195 VAL 195 196 196 VAL VAL A . n 
A 1 196 GLN 196 197 197 GLN GLN A . n 
A 1 197 LEU 197 198 198 LEU LEU A . n 
A 1 198 THR 198 199 199 THR THR A . n 
A 1 199 ASP 199 200 200 ASP ASP A . n 
A 1 200 LYS 200 201 201 LYS LYS A . n 
A 1 201 TYR 201 202 202 TYR TYR A . n 
A 1 202 CYS 202 203 203 CYS CYS A . n 
A 1 203 SER 203 204 204 SER SER A . n 
A 1 204 VAL 204 205 205 VAL VAL A . n 
A 1 205 ASN 205 206 206 ASN ASN A . n 
A 1 206 VAL 206 207 207 VAL VAL A . n 
A 1 207 VAL 207 208 208 VAL VAL A . n 
A 1 208 ALA 208 209 209 ALA ALA A . n 
A 1 209 TRP 209 210 210 TRP TRP A . n 
A 1 210 LEU 210 211 211 LEU LEU A . n 
A 1 211 TYR 211 212 212 TYR TYR A . n 
A 1 212 ALA 212 213 213 ALA ALA A . n 
A 1 213 ALA 213 214 214 ALA ALA A . n 
A 1 214 ILE 214 215 215 ILE ILE A . n 
A 1 215 LEU 215 216 216 LEU LEU A . n 
A 1 216 ASN 216 217 217 ASN ASN A . n 
A 1 217 GLY 217 218 218 GLY GLY A . n 
A 1 218 CYS 218 219 219 CYS CYS A . n 
A 1 219 ALA 219 220 220 ALA ALA A . n 
A 1 220 TRP 220 221 221 TRP TRP A . n 
A 1 221 PHE 221 222 222 PHE PHE A . n 
A 1 222 VAL 222 223 223 VAL VAL A . n 
A 1 223 LYS 223 224 224 LYS LYS A . n 
A 1 224 PRO 224 225 225 PRO PRO A . n 
A 1 225 ASN 225 226 226 ASN ASN A . n 
A 1 226 ARG 226 227 227 ARG ARG A . n 
A 1 227 THR 227 228 228 THR THR A . n 
A 1 228 SER 228 229 229 SER SER A . n 
A 1 229 VAL 229 230 230 VAL VAL A . n 
A 1 230 VAL 230 231 231 VAL VAL A . n 
A 1 231 SER 231 232 232 SER SER A . n 
A 1 232 PHE 232 233 233 PHE PHE A . n 
A 1 233 ASN 233 234 234 ASN ASN A . n 
A 1 234 GLU 234 235 235 GLU GLU A . n 
A 1 235 TRP 235 236 236 TRP TRP A . n 
A 1 236 ALA 236 237 237 ALA ALA A . n 
A 1 237 LEU 237 238 238 LEU LEU A . n 
A 1 238 ALA 238 239 239 ALA ALA A . n 
A 1 239 ASN 239 240 240 ASN ASN A . n 
A 1 240 GLN 240 241 241 GLN GLN A . n 
A 1 241 PHE 241 242 242 PHE PHE A . n 
A 1 242 THR 242 243 243 THR THR A . n 
A 1 243 GLU 243 244 244 GLU GLU A . n 
A 1 244 PHE 244 245 245 PHE PHE A . n 
A 1 245 VAL 245 246 246 VAL VAL A . n 
A 1 246 GLY 246 247 247 GLY GLY A . n 
A 1 247 THR 247 248 248 THR THR A . n 
A 1 248 GLN 248 249 249 GLN GLN A . n 
A 1 249 SER 249 250 250 SER SER A . n 
A 1 250 VAL 250 251 251 VAL VAL A . n 
A 1 251 ASP 251 252 252 ASP ASP A . n 
A 1 252 MET 252 253 253 MET MET A . n 
A 1 253 LEU 253 254 254 LEU LEU A . n 
A 1 254 ALA 254 255 255 ALA ALA A . n 
A 1 255 VAL 255 256 256 VAL VAL A . n 
A 1 256 LYS 256 257 257 LYS LYS A . n 
A 1 257 THR 257 258 258 THR THR A . n 
A 1 258 GLY 258 259 259 GLY GLY A . n 
A 1 259 VAL 259 260 260 VAL VAL A . n 
A 1 260 ALA 260 261 261 ALA ALA A . n 
A 1 261 ILE 261 262 262 ILE ILE A . n 
A 1 262 GLU 262 263 263 GLU GLU A . n 
A 1 263 GLN 263 264 264 GLN GLN A . n 
A 1 264 LEU 264 265 265 LEU LEU A . n 
A 1 265 LEU 265 266 266 LEU LEU A . n 
A 1 266 TYR 266 267 267 TYR TYR A . n 
A 1 267 ALA 267 268 268 ALA ALA A . n 
A 1 268 ILE 268 269 269 ILE ILE A . n 
A 1 269 GLN 269 270 270 GLN GLN A . n 
A 1 270 GLN 270 271 271 GLN GLN A . n 
A 1 271 LEU 271 272 272 LEU LEU A . n 
A 1 272 TYR 272 273 273 TYR TYR A . n 
A 1 273 THR 273 274 274 THR THR A . n 
A 1 274 GLY 274 275 275 GLY GLY A . n 
A 1 275 PHE 275 276 276 PHE PHE A . n 
A 1 276 GLN 276 277 277 GLN GLN A . n 
A 1 277 GLY 277 278 278 GLY GLY A . n 
A 1 278 LYS 278 279 279 LYS LYS A . n 
A 1 279 GLN 279 280 280 GLN GLN A . n 
A 1 280 ILE 280 281 281 ILE ILE A . n 
A 1 281 LEU 281 282 282 LEU LEU A . n 
A 1 282 GLY 282 283 283 GLY GLY A . n 
A 1 283 SER 283 284 284 SER SER A . n 
A 1 284 THR 284 285 285 THR THR A . n 
A 1 285 MET 285 286 286 MET MET A . n 
A 1 286 LEU 286 287 287 LEU LEU A . n 
A 1 287 GLU 287 288 288 GLU GLU A . n 
A 1 288 ASP 288 289 289 ASP ASP A . n 
A 1 289 GLU 289 290 290 GLU GLU A . n 
A 1 290 PHE 290 291 291 PHE PHE A . n 
A 1 291 THR 291 292 292 THR THR A . n 
A 1 292 PRO 292 293 293 PRO PRO A . n 
A 1 293 GLU 293 294 294 GLU GLU A . n 
A 1 294 ASP 294 295 295 ASP ASP A . n 
A 1 295 VAL 295 296 296 VAL VAL A . n 
A 1 296 ASN 296 297 297 ASN ASN A . n 
A 1 297 MET 297 298 298 MET MET A . n 
A 1 298 GLN 298 299 299 GLN GLN A . n 
A 1 299 ILE 299 300 300 ILE ILE A . n 
A 1 300 MET 300 301 301 MET MET A . n 
B 1 1   GLY 1   2   2   GLY GLY B . n 
B 1 2   LEU 2   3   3   LEU LEU B . n 
B 1 3   VAL 3   4   4   VAL VAL B . n 
B 1 4   LYS 4   5   5   LYS LYS B . n 
B 1 5   MET 5   6   6   MET MET B . n 
B 1 6   SER 6   7   7   SER SER B . n 
B 1 7   HIS 7   8   8   HIS HIS B . n 
B 1 8   PRO 8   9   9   PRO PRO B . n 
B 1 9   SER 9   10  10  SER SER B . n 
B 1 10  GLY 10  11  11  GLY GLY B . n 
B 1 11  ASP 11  12  12  ASP ASP B . n 
B 1 12  VAL 12  13  13  VAL VAL B . n 
B 1 13  GLU 13  14  14  GLU GLU B . n 
B 1 14  ALA 14  15  15  ALA ALA B . n 
B 1 15  CYS 15  16  16  CYS CYS B . n 
B 1 16  MET 16  17  17  MET MET B . n 
B 1 17  VAL 17  18  18  VAL VAL B . n 
B 1 18  GLN 18  19  19  GLN GLN B . n 
B 1 19  VAL 19  20  20  VAL VAL B . n 
B 1 20  THR 20  21  21  THR THR B . n 
B 1 21  CYS 21  22  22  CYS CYS B . n 
B 1 22  GLY 22  23  23  GLY GLY B . n 
B 1 23  SER 23  24  24  SER SER B . n 
B 1 24  MET 24  25  25  MET MET B . n 
B 1 25  THR 25  26  26  THR THR B . n 
B 1 26  LEU 26  27  27  LEU LEU B . n 
B 1 27  ASN 27  28  28  ASN ASN B . n 
B 1 28  GLY 28  29  29  GLY GLY B . n 
B 1 29  LEU 29  30  30  LEU LEU B . n 
B 1 30  TRP 30  31  31  TRP TRP B . n 
B 1 31  LEU 31  32  32  LEU LEU B . n 
B 1 32  ASP 32  33  33  ASP ASP B . n 
B 1 33  ASN 33  34  34  ASN ASN B . n 
B 1 34  THR 34  35  35  THR THR B . n 
B 1 35  VAL 35  36  36  VAL VAL B . n 
B 1 36  TRP 36  37  37  TRP TRP B . n 
B 1 37  CYS 37  38  38  CYS CYS B . n 
B 1 38  PRO 38  39  39  PRO PRO B . n 
B 1 39  ARG 39  40  40  ARG ARG B . n 
B 1 40  HIS 40  41  41  HIS HIS B . n 
B 1 41  VAL 41  42  42  VAL VAL B . n 
B 1 42  MET 42  43  43  MET MET B . n 
B 1 43  CYS 43  44  44  CYS CYS B . n 
B 1 44  PRO 44  45  45  PRO PRO B . n 
B 1 45  ALA 45  46  46  ALA ALA B . n 
B 1 46  ASP 46  47  47  ASP ASP B . n 
B 1 47  GLN 47  48  48  GLN GLN B . n 
B 1 48  LEU 48  49  49  LEU LEU B . n 
B 1 49  SER 49  50  50  SER SER B . n 
B 1 50  ASP 50  51  51  ASP ASP B . n 
B 1 51  PRO 51  52  52  PRO PRO B . n 
B 1 52  ASN 52  53  53  ASN ASN B . n 
B 1 53  TYR 53  54  54  TYR TYR B . n 
B 1 54  ASP 54  55  55  ASP ASP B . n 
B 1 55  ALA 55  56  56  ALA ALA B . n 
B 1 56  LEU 56  57  57  LEU LEU B . n 
B 1 57  LEU 57  58  58  LEU LEU B . n 
B 1 58  ILE 58  59  59  ILE ILE B . n 
B 1 59  SER 59  60  60  SER SER B . n 
B 1 60  MET 60  61  61  MET MET B . n 
B 1 61  THR 61  62  62  THR THR B . n 
B 1 62  ASN 62  63  63  ASN ASN B . n 
B 1 63  HIS 63  64  64  HIS HIS B . n 
B 1 64  SER 64  65  65  SER SER B . n 
B 1 65  PHE 65  66  66  PHE PHE B . n 
B 1 66  SER 66  67  67  SER SER B . n 
B 1 67  VAL 67  68  68  VAL VAL B . n 
B 1 68  GLN 68  69  69  GLN GLN B . n 
B 1 69  LYS 69  70  70  LYS LYS B . n 
B 1 70  HIS 70  71  71  HIS HIS B . n 
B 1 71  ILE 71  72  72  ILE ILE B . n 
B 1 72  GLY 72  73  73  GLY GLY B . n 
B 1 73  ALA 73  74  74  ALA ALA B . n 
B 1 74  PRO 74  75  75  PRO PRO B . n 
B 1 75  ALA 75  76  76  ALA ALA B . n 
B 1 76  ASN 76  77  77  ASN ASN B . n 
B 1 77  LEU 77  78  78  LEU LEU B . n 
B 1 78  ARG 78  79  79  ARG ARG B . n 
B 1 79  VAL 79  80  80  VAL VAL B . n 
B 1 80  VAL 80  81  81  VAL VAL B . n 
B 1 81  GLY 81  82  82  GLY GLY B . n 
B 1 82  HIS 82  83  83  HIS HIS B . n 
B 1 83  ALA 83  84  84  ALA ALA B . n 
B 1 84  MET 84  85  85  MET MET B . n 
B 1 85  GLN 85  86  86  GLN GLN B . n 
B 1 86  GLY 86  87  87  GLY GLY B . n 
B 1 87  THR 87  88  88  THR THR B . n 
B 1 88  LEU 88  89  89  LEU LEU B . n 
B 1 89  LEU 89  90  90  LEU LEU B . n 
B 1 90  LYS 90  91  91  LYS LYS B . n 
B 1 91  LEU 91  92  92  LEU LEU B . n 
B 1 92  THR 92  93  93  THR THR B . n 
B 1 93  VAL 93  94  94  VAL VAL B . n 
B 1 94  ASP 94  95  95  ASP ASP B . n 
B 1 95  VAL 95  96  96  VAL VAL B . n 
B 1 96  ALA 96  97  97  ALA ALA B . n 
B 1 97  ASN 97  98  98  ASN ASN B . n 
B 1 98  PRO 98  99  99  PRO PRO B . n 
B 1 99  SER 99  100 100 SER SER B . n 
B 1 100 THR 100 101 101 THR THR B . n 
B 1 101 PRO 101 102 102 PRO PRO B . n 
B 1 102 ALA 102 103 103 ALA ALA B . n 
B 1 103 TYR 103 104 104 TYR TYR B . n 
B 1 104 THR 104 105 105 THR THR B . n 
B 1 105 PHE 105 106 106 PHE PHE B . n 
B 1 106 THR 106 107 107 THR THR B . n 
B 1 107 THR 107 108 108 THR THR B . n 
B 1 108 VAL 108 109 109 VAL VAL B . n 
B 1 109 LYS 109 110 110 LYS LYS B . n 
B 1 110 PRO 110 111 111 PRO PRO B . n 
B 1 111 GLY 111 112 112 GLY GLY B . n 
B 1 112 ALA 112 113 113 ALA ALA B . n 
B 1 113 ALA 113 114 114 ALA ALA B . n 
B 1 114 PHE 114 115 115 PHE PHE B . n 
B 1 115 SER 115 116 116 SER SER B . n 
B 1 116 VAL 116 117 117 VAL VAL B . n 
B 1 117 LEU 117 118 118 LEU LEU B . n 
B 1 118 ALA 118 119 119 ALA ALA B . n 
B 1 119 CYS 119 120 120 CYS CYS B . n 
B 1 120 TYR 120 121 121 TYR TYR B . n 
B 1 121 ASN 121 122 122 ASN ASN B . n 
B 1 122 GLY 122 123 123 GLY GLY B . n 
B 1 123 ARG 123 124 124 ARG ARG B . n 
B 1 124 PRO 124 125 125 PRO PRO B . n 
B 1 125 THR 125 126 126 THR THR B . n 
B 1 126 GLY 126 127 127 GLY GLY B . n 
B 1 127 THR 127 128 128 THR THR B . n 
B 1 128 PHE 128 129 129 PHE PHE B . n 
B 1 129 THR 129 130 130 THR THR B . n 
B 1 130 VAL 130 131 131 VAL VAL B . n 
B 1 131 VAL 131 132 132 VAL VAL B . n 
B 1 132 MET 132 133 133 MET MET B . n 
B 1 133 ARG 133 134 134 ARG ARG B . n 
B 1 134 PRO 134 135 135 PRO PRO B . n 
B 1 135 ASN 135 136 136 ASN ASN B . n 
B 1 136 TYR 136 137 137 TYR TYR B . n 
B 1 137 THR 137 138 138 THR THR B . n 
B 1 138 ILE 138 139 139 ILE ILE B . n 
B 1 139 LYS 139 140 140 LYS LYS B . n 
B 1 140 GLY 140 141 141 GLY GLY B . n 
B 1 141 SER 141 142 142 SER SER B . n 
B 1 142 PHE 142 143 143 PHE PHE B . n 
B 1 143 LEU 143 144 144 LEU LEU B . n 
B 1 144 CYS 144 145 145 CYS CYS B . n 
B 1 145 GLY 145 146 146 GLY GLY B . n 
B 1 146 SER 146 147 147 SER SER B . n 
B 1 147 ALA 147 148 148 ALA ALA B . n 
B 1 148 GLY 148 149 149 GLY GLY B . n 
B 1 149 SER 149 150 150 SER SER B . n 
B 1 150 VAL 150 151 151 VAL VAL B . n 
B 1 151 GLY 151 152 152 GLY GLY B . n 
B 1 152 TYR 152 153 153 TYR TYR B . n 
B 1 153 THR 153 154 154 THR THR B . n 
B 1 154 LYS 154 155 155 LYS LYS B . n 
B 1 155 GLU 155 156 156 GLU GLU B . n 
B 1 156 GLY 156 157 157 GLY GLY B . n 
B 1 157 SER 157 158 158 SER SER B . n 
B 1 158 VAL 158 159 159 VAL VAL B . n 
B 1 159 ILE 159 160 160 ILE ILE B . n 
B 1 160 ASN 160 161 161 ASN ASN B . n 
B 1 161 PHE 161 162 162 PHE PHE B . n 
B 1 162 CYS 162 163 163 CYS CYS B . n 
B 1 163 TYR 163 164 164 TYR TYR B . n 
B 1 164 MET 164 165 165 MET MET B . n 
B 1 165 HIS 165 166 166 HIS HIS B . n 
B 1 166 GLN 166 167 167 GLN GLN B . n 
B 1 167 MET 167 168 168 MET MET B . n 
B 1 168 GLU 168 169 169 GLU GLU B . n 
B 1 169 LEU 169 170 170 LEU LEU B . n 
B 1 170 ALA 170 171 171 ALA ALA B . n 
B 1 171 ASN 171 172 172 ASN ASN B . n 
B 1 172 GLY 172 173 173 GLY GLY B . n 
B 1 173 THR 173 174 174 THR THR B . n 
B 1 174 HIS 174 175 175 HIS HIS B . n 
B 1 175 THR 175 176 176 THR THR B . n 
B 1 176 GLY 176 177 177 GLY GLY B . n 
B 1 177 SER 177 178 178 SER SER B . n 
B 1 178 ALA 178 179 179 ALA ALA B . n 
B 1 179 PHE 179 180 180 PHE PHE B . n 
B 1 180 ASP 180 181 181 ASP ASP B . n 
B 1 181 GLY 181 182 182 GLY GLY B . n 
B 1 182 THR 182 183 183 THR THR B . n 
B 1 183 MET 183 184 184 MET MET B . n 
B 1 184 TYR 184 185 185 TYR TYR B . n 
B 1 185 GLY 185 186 186 GLY GLY B . n 
B 1 186 ALA 186 187 187 ALA ALA B . n 
B 1 187 PHE 187 188 188 PHE PHE B . n 
B 1 188 MET 188 189 189 MET MET B . n 
B 1 189 ASP 189 190 190 ASP ASP B . n 
B 1 190 LYS 190 191 191 LYS LYS B . n 
B 1 191 GLN 191 192 192 GLN GLN B . n 
B 1 192 VAL 192 193 193 VAL VAL B . n 
B 1 193 HIS 193 194 194 HIS HIS B . n 
B 1 194 GLN 194 195 195 GLN GLN B . n 
B 1 195 VAL 195 196 196 VAL VAL B . n 
B 1 196 GLN 196 197 197 GLN GLN B . n 
B 1 197 LEU 197 198 198 LEU LEU B . n 
B 1 198 THR 198 199 199 THR THR B . n 
B 1 199 ASP 199 200 200 ASP ASP B . n 
B 1 200 LYS 200 201 201 LYS LYS B . n 
B 1 201 TYR 201 202 202 TYR TYR B . n 
B 1 202 CYS 202 203 203 CYS CYS B . n 
B 1 203 SER 203 204 204 SER SER B . n 
B 1 204 VAL 204 205 205 VAL VAL B . n 
B 1 205 ASN 205 206 206 ASN ASN B . n 
B 1 206 VAL 206 207 207 VAL VAL B . n 
B 1 207 VAL 207 208 208 VAL VAL B . n 
B 1 208 ALA 208 209 209 ALA ALA B . n 
B 1 209 TRP 209 210 210 TRP TRP B . n 
B 1 210 LEU 210 211 211 LEU LEU B . n 
B 1 211 TYR 211 212 212 TYR TYR B . n 
B 1 212 ALA 212 213 213 ALA ALA B . n 
B 1 213 ALA 213 214 214 ALA ALA B . n 
B 1 214 ILE 214 215 215 ILE ILE B . n 
B 1 215 LEU 215 216 216 LEU LEU B . n 
B 1 216 ASN 216 217 217 ASN ASN B . n 
B 1 217 GLY 217 218 218 GLY GLY B . n 
B 1 218 CYS 218 219 219 CYS CYS B . n 
B 1 219 ALA 219 220 220 ALA ALA B . n 
B 1 220 TRP 220 221 221 TRP TRP B . n 
B 1 221 PHE 221 222 222 PHE PHE B . n 
B 1 222 VAL 222 223 223 VAL VAL B . n 
B 1 223 LYS 223 224 224 LYS LYS B . n 
B 1 224 PRO 224 225 225 PRO PRO B . n 
B 1 225 ASN 225 226 226 ASN ASN B . n 
B 1 226 ARG 226 227 227 ARG ARG B . n 
B 1 227 THR 227 228 228 THR THR B . n 
B 1 228 SER 228 229 229 SER SER B . n 
B 1 229 VAL 229 230 230 VAL VAL B . n 
B 1 230 VAL 230 231 231 VAL VAL B . n 
B 1 231 SER 231 232 232 SER SER B . n 
B 1 232 PHE 232 233 233 PHE PHE B . n 
B 1 233 ASN 233 234 234 ASN ASN B . n 
B 1 234 GLU 234 235 235 GLU GLU B . n 
B 1 235 TRP 235 236 236 TRP TRP B . n 
B 1 236 ALA 236 237 237 ALA ALA B . n 
B 1 237 LEU 237 238 238 LEU LEU B . n 
B 1 238 ALA 238 239 239 ALA ALA B . n 
B 1 239 ASN 239 240 240 ASN ASN B . n 
B 1 240 GLN 240 241 241 GLN GLN B . n 
B 1 241 PHE 241 242 242 PHE PHE B . n 
B 1 242 THR 242 243 243 THR THR B . n 
B 1 243 GLU 243 244 244 GLU GLU B . n 
B 1 244 PHE 244 245 245 PHE PHE B . n 
B 1 245 VAL 245 246 246 VAL VAL B . n 
B 1 246 GLY 246 247 247 GLY GLY B . n 
B 1 247 THR 247 248 248 THR THR B . n 
B 1 248 GLN 248 249 249 GLN GLN B . n 
B 1 249 SER 249 250 250 SER SER B . n 
B 1 250 VAL 250 251 251 VAL VAL B . n 
B 1 251 ASP 251 252 252 ASP ASP B . n 
B 1 252 MET 252 253 253 MET MET B . n 
B 1 253 LEU 253 254 254 LEU LEU B . n 
B 1 254 ALA 254 255 255 ALA ALA B . n 
B 1 255 VAL 255 256 256 VAL VAL B . n 
B 1 256 LYS 256 257 257 LYS LYS B . n 
B 1 257 THR 257 258 258 THR THR B . n 
B 1 258 GLY 258 259 259 GLY GLY B . n 
B 1 259 VAL 259 260 260 VAL VAL B . n 
B 1 260 ALA 260 261 261 ALA ALA B . n 
B 1 261 ILE 261 262 262 ILE ILE B . n 
B 1 262 GLU 262 263 263 GLU GLU B . n 
B 1 263 GLN 263 264 264 GLN GLN B . n 
B 1 264 LEU 264 265 265 LEU LEU B . n 
B 1 265 LEU 265 266 266 LEU LEU B . n 
B 1 266 TYR 266 267 267 TYR TYR B . n 
B 1 267 ALA 267 268 268 ALA ALA B . n 
B 1 268 ILE 268 269 269 ILE ILE B . n 
B 1 269 GLN 269 270 270 GLN GLN B . n 
B 1 270 GLN 270 271 271 GLN GLN B . n 
B 1 271 LEU 271 272 272 LEU LEU B . n 
B 1 272 TYR 272 273 273 TYR TYR B . n 
B 1 273 THR 273 274 274 THR THR B . n 
B 1 274 GLY 274 275 275 GLY GLY B . n 
B 1 275 PHE 275 276 276 PHE PHE B . n 
B 1 276 GLN 276 277 277 GLN GLN B . n 
B 1 277 GLY 277 278 278 GLY GLY B . n 
B 1 278 LYS 278 279 279 LYS LYS B . n 
B 1 279 GLN 279 280 280 GLN GLN B . n 
B 1 280 ILE 280 281 281 ILE ILE B . n 
B 1 281 LEU 281 282 282 LEU LEU B . n 
B 1 282 GLY 282 283 283 GLY GLY B . n 
B 1 283 SER 283 284 284 SER SER B . n 
B 1 284 THR 284 285 285 THR THR B . n 
B 1 285 MET 285 286 286 MET MET B . n 
B 1 286 LEU 286 287 287 LEU LEU B . n 
B 1 287 GLU 287 288 288 GLU GLU B . n 
B 1 288 ASP 288 289 289 ASP ASP B . n 
B 1 289 GLU 289 290 290 GLU GLU B . n 
B 1 290 PHE 290 291 291 PHE PHE B . n 
B 1 291 THR 291 292 292 THR THR B . n 
B 1 292 PRO 292 293 293 PRO PRO B . n 
B 1 293 GLU 293 294 294 GLU GLU B . n 
B 1 294 ASP 294 295 295 ASP ASP B . n 
B 1 295 VAL 295 296 296 VAL VAL B . n 
B 1 296 ASN 296 297 297 ASN ASN B . n 
B 1 297 MET 297 298 298 MET MET B . n 
B 1 298 GLN 298 299 299 GLN GLN B . n 
B 1 299 ILE 299 300 300 ILE ILE B . n 
B 1 300 MET 300 301 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        X77 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   X77 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 X77 1   401 1   X77 LIG A . 
D 2 X77 1   401 2   X77 LIG B . 
E 3 HOH 1   501 71  HOH HOH A . 
E 3 HOH 2   502 5   HOH HOH A . 
E 3 HOH 3   503 24  HOH HOH A . 
E 3 HOH 4   504 109 HOH HOH A . 
E 3 HOH 5   505 175 HOH HOH A . 
E 3 HOH 6   506 131 HOH HOH A . 
E 3 HOH 7   507 99  HOH HOH A . 
E 3 HOH 8   508 142 HOH HOH A . 
E 3 HOH 9   509 169 HOH HOH A . 
E 3 HOH 10  510 79  HOH HOH A . 
E 3 HOH 11  511 26  HOH HOH A . 
E 3 HOH 12  512 73  HOH HOH A . 
E 3 HOH 13  513 48  HOH HOH A . 
E 3 HOH 14  514 135 HOH HOH A . 
E 3 HOH 15  515 179 HOH HOH A . 
E 3 HOH 16  516 139 HOH HOH A . 
E 3 HOH 17  517 36  HOH HOH A . 
E 3 HOH 18  518 127 HOH HOH A . 
E 3 HOH 19  519 68  HOH HOH A . 
E 3 HOH 20  520 86  HOH HOH A . 
E 3 HOH 21  521 46  HOH HOH A . 
E 3 HOH 22  522 51  HOH HOH A . 
E 3 HOH 23  523 114 HOH HOH A . 
E 3 HOH 24  524 107 HOH HOH A . 
E 3 HOH 25  525 11  HOH HOH A . 
E 3 HOH 26  526 18  HOH HOH A . 
E 3 HOH 27  527 49  HOH HOH A . 
E 3 HOH 28  528 55  HOH HOH A . 
E 3 HOH 29  529 35  HOH HOH A . 
E 3 HOH 30  530 141 HOH HOH A . 
E 3 HOH 31  531 23  HOH HOH A . 
E 3 HOH 32  532 6   HOH HOH A . 
E 3 HOH 33  533 7   HOH HOH A . 
E 3 HOH 34  534 95  HOH HOH A . 
E 3 HOH 35  535 106 HOH HOH A . 
E 3 HOH 36  536 16  HOH HOH A . 
E 3 HOH 37  537 119 HOH HOH A . 
E 3 HOH 38  538 130 HOH HOH A . 
E 3 HOH 39  539 40  HOH HOH A . 
E 3 HOH 40  540 9   HOH HOH A . 
E 3 HOH 41  541 156 HOH HOH A . 
E 3 HOH 42  542 32  HOH HOH A . 
E 3 HOH 43  543 177 HOH HOH A . 
E 3 HOH 44  544 108 HOH HOH A . 
E 3 HOH 45  545 120 HOH HOH A . 
E 3 HOH 46  546 98  HOH HOH A . 
E 3 HOH 47  547 80  HOH HOH A . 
E 3 HOH 48  548 185 HOH HOH A . 
E 3 HOH 49  549 154 HOH HOH A . 
E 3 HOH 50  550 3   HOH HOH A . 
E 3 HOH 51  551 29  HOH HOH A . 
E 3 HOH 52  552 17  HOH HOH A . 
E 3 HOH 53  553 58  HOH HOH A . 
E 3 HOH 54  554 111 HOH HOH A . 
E 3 HOH 55  555 88  HOH HOH A . 
E 3 HOH 56  556 54  HOH HOH A . 
E 3 HOH 57  557 164 HOH HOH A . 
E 3 HOH 58  558 168 HOH HOH A . 
E 3 HOH 59  559 52  HOH HOH A . 
E 3 HOH 60  560 102 HOH HOH A . 
E 3 HOH 61  561 85  HOH HOH A . 
E 3 HOH 62  562 122 HOH HOH A . 
E 3 HOH 63  563 42  HOH HOH A . 
E 3 HOH 64  564 183 HOH HOH A . 
E 3 HOH 65  565 25  HOH HOH A . 
E 3 HOH 66  566 121 HOH HOH A . 
E 3 HOH 67  567 78  HOH HOH A . 
E 3 HOH 68  568 13  HOH HOH A . 
E 3 HOH 69  569 124 HOH HOH A . 
E 3 HOH 70  570 10  HOH HOH A . 
E 3 HOH 71  571 174 HOH HOH A . 
E 3 HOH 72  572 105 HOH HOH A . 
E 3 HOH 73  573 172 HOH HOH A . 
E 3 HOH 74  574 171 HOH HOH A . 
E 3 HOH 75  575 126 HOH HOH A . 
E 3 HOH 76  576 123 HOH HOH A . 
E 3 HOH 77  577 20  HOH HOH A . 
E 3 HOH 78  578 90  HOH HOH A . 
E 3 HOH 79  579 66  HOH HOH A . 
E 3 HOH 80  580 100 HOH HOH A . 
E 3 HOH 81  581 147 HOH HOH A . 
E 3 HOH 82  582 34  HOH HOH A . 
E 3 HOH 83  583 82  HOH HOH A . 
E 3 HOH 84  584 158 HOH HOH A . 
E 3 HOH 85  585 57  HOH HOH A . 
E 3 HOH 86  586 31  HOH HOH A . 
E 3 HOH 87  587 112 HOH HOH A . 
E 3 HOH 88  588 125 HOH HOH A . 
E 3 HOH 89  589 4   HOH HOH A . 
E 3 HOH 90  590 75  HOH HOH A . 
E 3 HOH 91  591 45  HOH HOH A . 
E 3 HOH 92  592 134 HOH HOH A . 
E 3 HOH 93  593 8   HOH HOH A . 
E 3 HOH 94  594 113 HOH HOH A . 
E 3 HOH 95  595 33  HOH HOH A . 
E 3 HOH 96  596 53  HOH HOH A . 
E 3 HOH 97  597 117 HOH HOH A . 
E 3 HOH 98  598 133 HOH HOH A . 
E 3 HOH 99  599 104 HOH HOH A . 
E 3 HOH 100 600 62  HOH HOH A . 
E 3 HOH 101 601 103 HOH HOH A . 
E 3 HOH 102 602 59  HOH HOH A . 
E 3 HOH 103 603 145 HOH HOH A . 
E 3 HOH 104 604 157 HOH HOH A . 
E 3 HOH 105 605 180 HOH HOH A . 
E 3 HOH 106 606 173 HOH HOH A . 
E 3 HOH 107 607 166 HOH HOH A . 
E 3 HOH 108 608 161 HOH HOH A . 
E 3 HOH 109 609 167 HOH HOH A . 
E 3 HOH 110 610 144 HOH HOH A . 
E 3 HOH 111 611 137 HOH HOH A . 
E 3 HOH 112 612 153 HOH HOH A . 
E 3 HOH 113 613 70  HOH HOH A . 
E 3 HOH 114 614 150 HOH HOH A . 
E 3 HOH 115 615 44  HOH HOH A . 
E 3 HOH 116 616 146 HOH HOH A . 
E 3 HOH 117 617 74  HOH HOH A . 
F 3 HOH 1   501 143 HOH HOH B . 
F 3 HOH 2   502 165 HOH HOH B . 
F 3 HOH 3   503 87  HOH HOH B . 
F 3 HOH 4   504 61  HOH HOH B . 
F 3 HOH 5   505 91  HOH HOH B . 
F 3 HOH 6   506 64  HOH HOH B . 
F 3 HOH 7   507 60  HOH HOH B . 
F 3 HOH 8   508 148 HOH HOH B . 
F 3 HOH 9   509 63  HOH HOH B . 
F 3 HOH 10  510 43  HOH HOH B . 
F 3 HOH 11  511 186 HOH HOH B . 
F 3 HOH 12  512 160 HOH HOH B . 
F 3 HOH 13  513 92  HOH HOH B . 
F 3 HOH 14  514 81  HOH HOH B . 
F 3 HOH 15  515 97  HOH HOH B . 
F 3 HOH 16  516 110 HOH HOH B . 
F 3 HOH 17  517 149 HOH HOH B . 
F 3 HOH 18  518 138 HOH HOH B . 
F 3 HOH 19  519 21  HOH HOH B . 
F 3 HOH 20  520 14  HOH HOH B . 
F 3 HOH 21  521 67  HOH HOH B . 
F 3 HOH 22  522 72  HOH HOH B . 
F 3 HOH 23  523 83  HOH HOH B . 
F 3 HOH 24  524 187 HOH HOH B . 
F 3 HOH 25  525 37  HOH HOH B . 
F 3 HOH 26  526 22  HOH HOH B . 
F 3 HOH 27  527 27  HOH HOH B . 
F 3 HOH 28  528 84  HOH HOH B . 
F 3 HOH 29  529 89  HOH HOH B . 
F 3 HOH 30  530 132 HOH HOH B . 
F 3 HOH 31  531 96  HOH HOH B . 
F 3 HOH 32  532 15  HOH HOH B . 
F 3 HOH 33  533 19  HOH HOH B . 
F 3 HOH 34  534 12  HOH HOH B . 
F 3 HOH 35  535 101 HOH HOH B . 
F 3 HOH 36  536 151 HOH HOH B . 
F 3 HOH 37  537 170 HOH HOH B . 
F 3 HOH 38  538 28  HOH HOH B . 
F 3 HOH 39  539 115 HOH HOH B . 
F 3 HOH 40  540 76  HOH HOH B . 
F 3 HOH 41  541 41  HOH HOH B . 
F 3 HOH 42  542 181 HOH HOH B . 
F 3 HOH 43  543 30  HOH HOH B . 
F 3 HOH 44  544 39  HOH HOH B . 
F 3 HOH 45  545 178 HOH HOH B . 
F 3 HOH 46  546 50  HOH HOH B . 
F 3 HOH 47  547 2   HOH HOH B . 
F 3 HOH 48  548 65  HOH HOH B . 
F 3 HOH 49  549 118 HOH HOH B . 
F 3 HOH 50  550 184 HOH HOH B . 
F 3 HOH 51  551 182 HOH HOH B . 
F 3 HOH 52  552 38  HOH HOH B . 
F 3 HOH 53  553 162 HOH HOH B . 
F 3 HOH 54  554 56  HOH HOH B . 
F 3 HOH 55  555 93  HOH HOH B . 
F 3 HOH 56  556 129 HOH HOH B . 
F 3 HOH 57  557 94  HOH HOH B . 
F 3 HOH 58  558 116 HOH HOH B . 
F 3 HOH 59  559 136 HOH HOH B . 
F 3 HOH 60  560 1   HOH HOH B . 
F 3 HOH 61  561 176 HOH HOH B . 
F 3 HOH 62  562 163 HOH HOH B . 
F 3 HOH 63  563 128 HOH HOH B . 
F 3 HOH 64  564 140 HOH HOH B . 
F 3 HOH 65  565 69  HOH HOH B . 
F 3 HOH 66  566 159 HOH HOH B . 
F 3 HOH 67  567 152 HOH HOH B . 
F 3 HOH 68  568 47  HOH HOH B . 
F 3 HOH 69  569 77  HOH HOH B . 
F 3 HOH 70  570 155 HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B GLN 192 ? CG  ? B GLN 191 CG  
2 1 Y 1 B GLN 192 ? CD  ? B GLN 191 CD  
3 1 Y 1 B GLN 192 ? OE1 ? B GLN 191 OE1 
4 1 Y 1 B GLN 192 ? NE2 ? B GLN 191 NE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.12_2829 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .         2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .         3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? .         4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8YKL 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     79.709 
_cell.length_a_esd                 ? 
_cell.length_b                     94.876 
_cell.length_b_esd                 ? 
_cell.length_c                     98.320 
_cell.length_c_esd                 ? 
_cell.volume                       743542.157 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8YKL 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8YKL 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.85 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          56.82 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2M Sodium formate, 0.1M BICINE pH8.5  20%  PEG5000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-04-30 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979183 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL02U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979183 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL02U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          28.3661025048 
_reflns.entry_id                                       8YKL 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.93 
_reflns.d_resolution_low                               36.94 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     55508 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.2 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          17.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.06 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.93 
_reflns_shell.d_res_low                                     2.04 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             8001 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.521 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               31.8685660534 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8YKL 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.93 
_refine.ls_d_res_low                             36.94 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     55425 
_refine.ls_number_reflns_R_free                  2864 
_refine.ls_number_reflns_R_work                  52561 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.1147105682 
_refine.ls_percent_reflns_R_free                 5.16734325665 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.202166698946 
_refine.ls_R_factor_R_free                       0.230093038165 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.200640719796 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33795957895 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 23.0108253096 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.220685310159 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.93 
_refine_hist.d_res_low                        36.94 
_refine_hist.number_atoms_solvent             187 
_refine_hist.number_atoms_total               4813 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4558 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         68 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.00684009601269 ? 4740 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.920940514487   ? 6458 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0547619836484  ? 731  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.00565256813951 ? 821  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 4.08413971147    ? 2738 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.9323 1.9656 . . 131 2507 95.5797101449 . . . . 0.25705349703  . . . . . . . . . . . 0.281049948463 
'X-RAY DIFFRACTION' 1.9656 2.0014 . . 127 2654 99.179743224  . . . . 0.24780471157  . . . . . . . . . . . 0.28752842282  
'X-RAY DIFFRACTION' 2.0014 2.0399 . . 152 2639 99.8211731044 . . . . 0.238074616453 . . . . . . . . . . . 0.25600705379  
'X-RAY DIFFRACTION' 2.0399 2.0815 . . 159 2602 99.8192335503 . . . . 0.225838329084 . . . . . . . . . . . 0.275846982963 
'X-RAY DIFFRACTION' 2.0815 2.1267 . . 125 2644 99.7837837838 . . . . 0.228909651693 . . . . . . . . . . . 0.230519178923 
'X-RAY DIFFRACTION' 2.1267 2.1762 . . 155 2649 99.9643493761 . . . . 0.223908088647 . . . . . . . . . . . 0.276926068328 
'X-RAY DIFFRACTION' 2.1762 2.2306 . . 126 2667 99.8569896317 . . . . 0.220613461983 . . . . . . . . . . . 0.2656108239   
'X-RAY DIFFRACTION' 2.2306 2.2909 . . 121 2115 79.6579978625 . . . . 0.220777847486 . . . . . . . . . . . 0.25980196948  
'X-RAY DIFFRACTION' 2.2909 2.3583 . . 150 2635 99.8923959828 . . . . 0.211062873115 . . . . . . . . . . . 0.273319030055 
'X-RAY DIFFRACTION' 2.3583 2.4344 . . 140 2687 99.9646393211 . . . . 0.228002841244 . . . . . . . . . . . 0.241465692582 
'X-RAY DIFFRACTION' 2.4344 2.5214 . . 139 2644 99.9281867145 . . . . 0.22832447134  . . . . . . . . . . . 0.242704620075 
'X-RAY DIFFRACTION' 2.5214 2.6224 . . 138 2673 99.9644381223 . . . . 0.232815712318 . . . . . . . . . . . 0.246627565933 
'X-RAY DIFFRACTION' 2.6224 2.7417 . . 185 2633 100.0         . . . . 0.228268853411 . . . . . . . . . . . 0.303037911329 
'X-RAY DIFFRACTION' 2.7417 2.8862 . . 142 2685 99.8587071706 . . . . 0.217842607188 . . . . . . . . . . . 0.233821624938 
'X-RAY DIFFRACTION' 2.8862 3.0669 . . 137 2678 99.8226950355 . . . . 0.225388534886 . . . . . . . . . . . 0.224076543063 
'X-RAY DIFFRACTION' 3.0669 3.3036 . . 153 2672 99.7880607559 . . . . 0.218734956889 . . . . . . . . . . . 0.270323742684 
'X-RAY DIFFRACTION' 3.3036 3.6358 . . 132 2613 95.7112970711 . . . . 0.200791043792 . . . . . . . . . . . 0.231360933946 
'X-RAY DIFFRACTION' 3.6358 4.1612 . . 129 2584 94.6945898778 . . . . 0.172710220375 . . . . . . . . . . . 0.200062459908 
'X-RAY DIFFRACTION' 4.1612 5.2403 . . 175 2717 99.7585374267 . . . . 0.149966243364 . . . . . . . . . . . 0.187129649244 
'X-RAY DIFFRACTION' 5.2403 36.94  . . 148 2863 99.3401517651 . . . . 0.167304108228 . . . . . . . . . . . 0.173033686184 
# 
_struct.entry_id                     8YKL 
_struct.title                        'Crystal structure of MERS main protease in complex with X77' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8YKL 
_struct_keywords.text            'VIRAL PROTEIN-INHIBITOR COMPLEX' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN/INHIBITOR' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    W5ZZG0_MERS 
_struct_ref.pdbx_db_accession          W5ZZG0 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;GLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVV
GHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVIN
FCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQ
FTEFVGTQSVDMLAVKTGVAIEQLLYAIQQLYTGFQGKQILGSTMLEDEFTPEDVNMQIM
;
_struct_ref.pdbx_align_begin           3249 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8YKL A 1 ? 300 ? W5ZZG0 3249 ? 3548 ? 2 301 
2 1 8YKL B 1 ? 300 ? W5ZZG0 3249 ? 3548 ? 2 301 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8YKL ALA A 147 ? UNP W5ZZG0 CYS 3395 'engineered mutation' 148 1 
2 8YKL ALA B 147 ? UNP W5ZZG0 CYS 3395 'engineered mutation' 148 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1820  ? 
1 MORE         -15   ? 
1 'SSA (A^2)'  24970 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 9   ? ALA A 14  ? SER A 10  ALA A 15  1 ? 6  
HELX_P HELX_P2  AA2 HIS A 40  ? CYS A 43  ? HIS A 41  CYS A 44  5 ? 4  
HELX_P HELX_P3  AA3 ASN A 52  ? MET A 60  ? ASN A 53  MET A 61  1 ? 9  
HELX_P HELX_P4  AA4 THR A 61  ? HIS A 63  ? THR A 62  HIS A 64  5 ? 3  
HELX_P HELX_P5  AA5 MET A 183 ? PHE A 187 ? MET A 184 PHE A 188 5 ? 5  
HELX_P HELX_P6  AA6 CYS A 202 ? ASN A 216 ? CYS A 203 ASN A 217 1 ? 15 
HELX_P HELX_P7  AA7 SER A 228 ? ALA A 238 ? SER A 229 ALA A 239 1 ? 11 
HELX_P HELX_P8  AA8 THR A 247 ? GLY A 258 ? THR A 248 GLY A 259 1 ? 12 
HELX_P HELX_P9  AA9 ALA A 260 ? THR A 273 ? ALA A 261 THR A 274 1 ? 14 
HELX_P HELX_P10 AB1 THR A 291 ? MET A 300 ? THR A 292 MET A 301 1 ? 10 
HELX_P HELX_P11 AB2 SER B 9   ? ALA B 14  ? SER B 10  ALA B 15  1 ? 6  
HELX_P HELX_P12 AB3 HIS B 40  ? CYS B 43  ? HIS B 41  CYS B 44  5 ? 4  
HELX_P HELX_P13 AB4 ASN B 52  ? MET B 60  ? ASN B 53  MET B 61  1 ? 9  
HELX_P HELX_P14 AB5 MET B 183 ? PHE B 187 ? MET B 184 PHE B 188 5 ? 5  
HELX_P HELX_P15 AB6 CYS B 202 ? ASN B 216 ? CYS B 203 ASN B 217 1 ? 15 
HELX_P HELX_P16 AB7 SER B 228 ? ASN B 239 ? SER B 229 ASN B 240 1 ? 12 
HELX_P HELX_P17 AB8 THR B 247 ? GLY B 258 ? THR B 248 GLY B 259 1 ? 12 
HELX_P HELX_P18 AB9 ALA B 260 ? GLY B 274 ? ALA B 261 GLY B 275 1 ? 15 
HELX_P HELX_P19 AC1 THR B 291 ? ILE B 299 ? THR B 292 ILE B 300 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          ALA 
_struct_mon_prot_cis.label_seq_id           75 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           ALA 
_struct_mon_prot_cis.auth_seq_id            76 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   ASN 
_struct_mon_prot_cis.pdbx_label_seq_id_2    76 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    ASN 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     77 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       1.92 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 5 ? 
AA3 ? 3 ? 
AA4 ? 7 ? 
AA5 ? 5 ? 
AA6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 75  ? LEU A 77  ? ALA A 76  LEU A 78  
AA1 2 PHE A 65  ? LYS A 69  ? PHE A 66  LYS A 70  
AA1 3 MET A 16  ? CYS A 21  ? MET A 17  CYS A 22  
AA1 4 MET A 24  ? LEU A 31  ? MET A 25  LEU A 32  
AA1 5 THR A 34  ? PRO A 38  ? THR A 35  PRO A 39  
AA1 6 LEU A 88  ? VAL A 93  ? LEU A 89  VAL A 94  
AA1 7 VAL A 79  ? GLN A 85  ? VAL A 80  GLN A 86  
AA2 1 TYR A 103 ? PHE A 105 ? TYR A 104 PHE A 106 
AA2 2 VAL A 158 ? GLU A 168 ? VAL A 159 GLU A 169 
AA2 3 VAL A 150 ? GLU A 155 ? VAL A 151 GLU A 156 
AA2 4 ALA A 113 ? TYR A 120 ? ALA A 114 TYR A 121 
AA2 5 ARG A 123 ? VAL A 131 ? ARG A 124 VAL A 132 
AA3 1 TYR A 103 ? PHE A 105 ? TYR A 104 PHE A 106 
AA3 2 VAL A 158 ? GLU A 168 ? VAL A 159 GLU A 169 
AA3 3 HIS A 174 ? SER A 177 ? HIS A 175 SER A 178 
AA4 1 ALA B 75  ? LEU B 77  ? ALA B 76  LEU B 78  
AA4 2 PHE B 65  ? LYS B 69  ? PHE B 66  LYS B 70  
AA4 3 MET B 16  ? CYS B 21  ? MET B 17  CYS B 22  
AA4 4 MET B 24  ? LEU B 31  ? MET B 25  LEU B 32  
AA4 5 THR B 34  ? PRO B 38  ? THR B 35  PRO B 39  
AA4 6 LEU B 88  ? VAL B 93  ? LEU B 89  VAL B 94  
AA4 7 VAL B 79  ? GLN B 85  ? VAL B 80  GLN B 86  
AA5 1 TYR B 103 ? PHE B 105 ? TYR B 104 PHE B 106 
AA5 2 VAL B 158 ? GLU B 168 ? VAL B 159 GLU B 169 
AA5 3 VAL B 150 ? GLU B 155 ? VAL B 151 GLU B 156 
AA5 4 ALA B 113 ? TYR B 120 ? ALA B 114 TYR B 121 
AA5 5 ARG B 123 ? VAL B 131 ? ARG B 124 VAL B 132 
AA6 1 TYR B 103 ? PHE B 105 ? TYR B 104 PHE B 106 
AA6 2 VAL B 158 ? GLU B 168 ? VAL B 159 GLU B 169 
AA6 3 HIS B 174 ? SER B 177 ? HIS B 175 SER B 178 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 75  ? O ALA A 76  N LYS A 69  ? N LYS A 70  
AA1 2 3 O GLN A 68  ? O GLN A 69  N GLN A 18  ? N GLN A 19  
AA1 3 4 N VAL A 19  ? N VAL A 20  O LEU A 26  ? O LEU A 27  
AA1 4 5 N LEU A 31  ? N LEU A 32  O THR A 34  ? O THR A 35  
AA1 5 6 N CYS A 37  ? N CYS A 38  O LEU A 89  ? O LEU A 90  
AA1 6 7 O THR A 92  ? O THR A 93  N VAL A 80  ? N VAL A 81  
AA2 1 2 N THR A 104 ? N THR A 105 O PHE A 161 ? O PHE A 162 
AA2 2 3 O TYR A 163 ? O TYR A 164 N GLY A 151 ? N GLY A 152 
AA2 3 4 O TYR A 152 ? O TYR A 153 N SER A 115 ? N SER A 116 
AA2 4 5 N VAL A 116 ? N VAL A 117 O PHE A 128 ? O PHE A 129 
AA3 1 2 N THR A 104 ? N THR A 105 O PHE A 161 ? O PHE A 162 
AA3 2 3 N MET A 167 ? N MET A 168 O THR A 175 ? O THR A 176 
AA4 1 2 O ALA B 75  ? O ALA B 76  N LYS B 69  ? N LYS B 70  
AA4 2 3 O SER B 66  ? O SER B 67  N THR B 20  ? N THR B 21  
AA4 3 4 N VAL B 19  ? N VAL B 20  O LEU B 26  ? O LEU B 27  
AA4 4 5 N LEU B 31  ? N LEU B 32  O THR B 34  ? O THR B 35  
AA4 5 6 N CYS B 37  ? N CYS B 38  O LEU B 89  ? O LEU B 90  
AA4 6 7 O THR B 92  ? O THR B 93  N VAL B 80  ? N VAL B 81  
AA5 1 2 N THR B 104 ? N THR B 105 O ILE B 159 ? O ILE B 160 
AA5 2 3 O ASN B 160 ? O ASN B 161 N THR B 153 ? N THR B 154 
AA5 3 4 O TYR B 152 ? O TYR B 153 N SER B 115 ? N SER B 116 
AA5 4 5 N VAL B 116 ? N VAL B 117 O PHE B 128 ? O PHE B 129 
AA6 1 2 N THR B 104 ? N THR B 105 O ILE B 159 ? O ILE B 160 
AA6 2 3 N MET B 164 ? N MET B 165 O SER B 177 ? O SER B 178 
# 
_pdbx_entry_details.entry_id                   8YKL 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 33  ? ? 52.77   -122.70 
2 1 ASP A 51  ? ? -152.60 58.69   
3 1 ALA A 76  ? ? 154.23  159.51  
4 1 ASN A 77  ? ? 79.60   63.69   
5 1 GLN A 277 ? ? 52.43   -127.78 
6 1 ASP B 33  ? ? 48.22   -123.60 
7 1 ASP B 51  ? ? -166.58 88.08   
8 1 ALA B 220 ? ? -140.45 21.61   
9 1 GLN B 277 ? ? 51.80   -118.82 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLY 2   ? A GLY 1   
2 1 Y 1 B MET 301 ? B MET 300 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
X77 C02  C N N 391 
X77 C04  C N R 392 
X77 C05  C N N 393 
X77 C07  C N N 394 
X77 C08  C N N 395 
X77 C09  C N N 396 
X77 C10  C N N 397 
X77 C11  C N N 398 
X77 C12  C N N 399 
X77 C14  C Y N 400 
X77 C15  C Y N 401 
X77 C16  C Y N 402 
X77 C17  C Y N 403 
X77 C19  C Y N 404 
X77 C20  C Y N 405 
X77 C21  C Y N 406 
X77 C22  C Y N 407 
X77 C23  C Y N 408 
X77 C24  C N N 409 
X77 C25  C N N 410 
X77 C26  C N N 411 
X77 C27  C N N 412 
X77 C28  C Y N 413 
X77 C29  C Y N 414 
X77 C30  C Y N 415 
X77 C31  C Y N 416 
X77 C33  C Y N 417 
X77 N03  N N N 418 
X77 N06  N N N 419 
X77 N18  N Y N 420 
X77 N32  N Y N 421 
X77 N34  N Y N 422 
X77 O01  O N N 423 
X77 O13  O N N 424 
X77 H041 H N N 425 
X77 H071 H N N 426 
X77 H081 H N N 427 
X77 H082 H N N 428 
X77 H091 H N N 429 
X77 H092 H N N 430 
X77 H101 H N N 431 
X77 H102 H N N 432 
X77 H112 H N N 433 
X77 H111 H N N 434 
X77 H121 H N N 435 
X77 H122 H N N 436 
X77 H151 H N N 437 
X77 H161 H N N 438 
X77 H171 H N N 439 
X77 H191 H N N 440 
X77 H211 H N N 441 
X77 H221 H N N 442 
X77 H251 H N N 443 
X77 H252 H N N 444 
X77 H253 H N N 445 
X77 H261 H N N 446 
X77 H263 H N N 447 
X77 H262 H N N 448 
X77 H272 H N N 449 
X77 H273 H N N 450 
X77 H271 H N N 451 
X77 H281 H N N 452 
X77 H291 H N N 453 
X77 H311 H N N 454 
X77 H331 H N N 455 
X77 H061 H N N 456 
X77 H1   H N N 457 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
X77 C33 N32  sing Y N 376 
X77 C33 N34  doub Y N 377 
X77 N32 C31  sing Y N 378 
X77 N34 C30  sing Y N 379 
X77 C31 C30  doub Y N 380 
X77 C30 C02  sing N N 381 
X77 C27 C24  sing N N 382 
X77 C02 O01  doub N N 383 
X77 C02 N03  sing N N 384 
X77 C26 C24  sing N N 385 
X77 C28 C29  doub Y N 386 
X77 C28 C23  sing Y N 387 
X77 C24 C23  sing N N 388 
X77 C24 C25  sing N N 389 
X77 C29 C20  sing Y N 390 
X77 C23 C22  doub Y N 391 
X77 C20 N03  sing N N 392 
X77 C20 C21  doub Y N 393 
X77 C22 C21  sing Y N 394 
X77 N03 C04  sing N N 395 
X77 C19 N18  doub Y N 396 
X77 C19 C14  sing Y N 397 
X77 C04 C14  sing N N 398 
X77 C04 C05  sing N N 399 
X77 N18 C17  sing Y N 400 
X77 C14 C15  doub Y N 401 
X77 O13 C05  doub N N 402 
X77 C17 C16  doub Y N 403 
X77 C05 N06  sing N N 404 
X77 C15 C16  sing Y N 405 
X77 N06 C07  sing N N 406 
X77 C12 C07  sing N N 407 
X77 C12 C11  sing N N 408 
X77 C07 C08  sing N N 409 
X77 C11 C10  sing N N 410 
X77 C08 C09  sing N N 411 
X77 C10 C09  sing N N 412 
X77 C04 H041 sing N N 413 
X77 C07 H071 sing N N 414 
X77 C08 H081 sing N N 415 
X77 C08 H082 sing N N 416 
X77 C09 H091 sing N N 417 
X77 C09 H092 sing N N 418 
X77 C10 H101 sing N N 419 
X77 C10 H102 sing N N 420 
X77 C11 H112 sing N N 421 
X77 C11 H111 sing N N 422 
X77 C12 H121 sing N N 423 
X77 C12 H122 sing N N 424 
X77 C15 H151 sing N N 425 
X77 C16 H161 sing N N 426 
X77 C17 H171 sing N N 427 
X77 C19 H191 sing N N 428 
X77 C21 H211 sing N N 429 
X77 C22 H221 sing N N 430 
X77 C25 H251 sing N N 431 
X77 C25 H252 sing N N 432 
X77 C25 H253 sing N N 433 
X77 C26 H261 sing N N 434 
X77 C26 H263 sing N N 435 
X77 C26 H262 sing N N 436 
X77 C27 H272 sing N N 437 
X77 C27 H273 sing N N 438 
X77 C27 H271 sing N N 439 
X77 C28 H281 sing N N 440 
X77 C29 H291 sing N N 441 
X77 C31 H311 sing N N 442 
X77 C33 H331 sing N N 443 
X77 N06 H061 sing N N 444 
X77 N32 H1   sing N N 445 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8HUT 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8YKL 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012546 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010540 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.010171 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 25.62398 1.50364  0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 19.97189 1.75589  0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 15.80542 1.70748  0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 1.23737  29.19336 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . LEU A 1 2   ? -14.15219 39.49058 -34.18309 1.000 39.97957 ? 3   LEU A N   1 
ATOM   2    C CA  . LEU A 1 2   ? -14.01173 38.94413 -32.82878 1.000 38.08543 ? 3   LEU A CA  1 
ATOM   3    C C   . LEU A 1 2   ? -15.21944 38.12362 -32.37618 1.000 35.99749 ? 3   LEU A C   1 
ATOM   4    O O   . LEU A 1 2   ? -16.12969 38.64291 -31.73102 1.000 39.31544 ? 3   LEU A O   1 
ATOM   5    C CB  . LEU A 1 2   ? -13.78197 40.07127 -31.82748 1.000 38.52194 ? 3   LEU A CB  1 
ATOM   6    C CG  . LEU A 1 2   ? -12.70750 39.79397 -30.77458 1.000 40.89838 ? 3   LEU A CG  1 
ATOM   7    C CD1 . LEU A 1 2   ? -11.39881 39.24543 -31.40861 1.000 32.46755 ? 3   LEU A CD1 1 
ATOM   8    C CD2 . LEU A 1 2   ? -12.43637 41.04446 -29.97669 1.000 31.80692 ? 3   LEU A CD2 1 
ATOM   9    N N   . VAL A 1 3   ? -15.21618 36.83423 -32.68258 1.000 31.75248 ? 4   VAL A N   1 
ATOM   10   C CA  . VAL A 1 3   ? -16.31014 35.96537 -32.29289 1.000 29.43768 ? 4   VAL A CA  1 
ATOM   11   C C   . VAL A 1 3   ? -15.83608 35.10612 -31.13206 1.000 26.38998 ? 4   VAL A C   1 
ATOM   12   O O   . VAL A 1 3   ? -14.63498 34.91894 -30.90724 1.000 27.54202 ? 4   VAL A O   1 
ATOM   13   C CB  . VAL A 1 3   ? -16.81844 35.08940 -33.46510 1.000 25.90178 ? 4   VAL A CB  1 
ATOM   14   C CG1 . VAL A 1 3   ? -17.07776 35.94046 -34.69780 1.000 29.57924 ? 4   VAL A CG1 1 
ATOM   15   C CG2 . VAL A 1 3   ? -15.81684 33.98580 -33.78835 1.000 27.21946 ? 4   VAL A CG2 1 
ATOM   16   N N   . LYS A 1 4   ? -16.79693 34.59243 -30.37740 1.000 23.63359 ? 5   LYS A N   1 
ATOM   17   C CA  . LYS A 1 4   ? -16.50692 33.54047 -29.40951 1.000 26.34690 ? 5   LYS A CA  1 
ATOM   18   C C   . LYS A 1 4   ? -16.18854 32.25945 -30.17138 1.000 26.02454 ? 5   LYS A C   1 
ATOM   19   O O   . LYS A 1 4   ? -17.08148 31.62725 -30.74557 1.000 23.33436 ? 5   LYS A O   1 
ATOM   20   C CB  . LYS A 1 4   ? -17.69048 33.34595 -28.46975 1.000 24.81950 ? 5   LYS A CB  1 
ATOM   21   C CG  . LYS A 1 4   ? -17.93453 34.55278 -27.55897 1.000 32.02859 ? 5   LYS A CG  1 
ATOM   22   C CD  . LYS A 1 4   ? -16.77938 34.74642 -26.58443 1.000 33.22584 ? 5   LYS A CD  1 
ATOM   23   C CE  . LYS A 1 4   ? -16.99512 35.98088 -25.70547 1.000 35.53811 ? 5   LYS A CE  1 
ATOM   24   N NZ  . LYS A 1 4   ? -18.05402 35.74481 -24.69032 1.000 39.49334 ? 5   LYS A NZ  1 
ATOM   25   N N   . MET A 1 5   ? -14.91761 31.88876 -30.19764 1.000 23.31929 ? 6   MET A N   1 
ATOM   26   C CA  . MET A 1 5   ? -14.45578 30.72253 -30.93163 1.000 22.08223 ? 6   MET A CA  1 
ATOM   27   C C   . MET A 1 5   ? -14.25588 29.54555 -29.97718 1.000 25.89847 ? 6   MET A C   1 
ATOM   28   O O   . MET A 1 5   ? -13.67249 29.70699 -28.89527 1.000 21.90423 ? 6   MET A O   1 
ATOM   29   C CB  . MET A 1 5   ? -13.15333 31.04729 -31.65757 1.000 20.16559 ? 6   MET A CB  1 
ATOM   30   C CG  . MET A 1 5   ? -12.65488 29.91933 -32.53590 1.000 29.87218 ? 6   MET A CG  1 
ATOM   31   S SD  . MET A 1 5   ? -13.32775 30.00106 -34.21217 1.000 36.15526 ? 6   MET A SD  1 
ATOM   32   C CE  . MET A 1 5   ? -12.74339 31.60791 -34.74030 1.000 26.12193 ? 6   MET A CE  1 
ATOM   33   N N   . SER A 1 6   ? -14.72809 28.36905 -30.38790 1.000 21.29473 ? 7   SER A N   1 
ATOM   34   C CA  . SER A 1 6   ? -14.45243 27.11032 -29.70587 1.000 21.94961 ? 7   SER A CA  1 
ATOM   35   C C   . SER A 1 6   ? -13.61025 26.19647 -30.59072 1.000 19.55436 ? 7   SER A C   1 
ATOM   36   O O   . SER A 1 6   ? -13.60494 26.31627 -31.82065 1.000 21.06332 ? 7   SER A O   1 
ATOM   37   C CB  . SER A 1 6   ? -15.75641 26.38810 -29.32614 1.000 21.85001 ? 7   SER A CB  1 
ATOM   38   O OG  . SER A 1 6   ? -16.46371 27.14372 -28.35422 1.000 23.85954 ? 7   SER A OG  1 
ATOM   39   N N   . HIS A 1 7   ? -12.91128 25.25250 -29.95640 1.000 18.86147 ? 8   HIS A N   1 
ATOM   40   C CA  . HIS A 1 7   ? -12.24271 24.21210 -30.72833 1.000 18.00053 ? 8   HIS A CA  1 
ATOM   41   C C   . HIS A 1 7   ? -13.29245 23.29785 -31.36453 1.000 19.82856 ? 8   HIS A C   1 
ATOM   42   O O   . HIS A 1 7   ? -14.39184 23.13214 -30.82945 1.000 21.00750 ? 8   HIS A O   1 
ATOM   43   C CB  . HIS A 1 7   ? -11.30545 23.38096 -29.84921 1.000 20.53046 ? 8   HIS A CB  1 
ATOM   44   C CG  . HIS A 1 7   ? -10.11830 24.13267 -29.31695 1.000 24.70801 ? 8   HIS A CG  1 
ATOM   45   N ND1 . HIS A 1 7   ? -9.07368  24.54869 -30.11919 1.000 24.59968 ? 8   HIS A ND1 1 
ATOM   46   C CD2 . HIS A 1 7   ? -9.78538  24.49268 -28.05268 1.000 24.13374 ? 8   HIS A CD2 1 
ATOM   47   C CE1 . HIS A 1 7   ? -8.16603  25.16054 -29.37791 1.000 25.41477 ? 8   HIS A CE1 1 
ATOM   48   N NE2 . HIS A 1 7   ? -8.56401  25.12306 -28.11639 1.000 23.01420 ? 8   HIS A NE2 1 
ATOM   49   N N   . PRO A 1 8   ? -12.99883 22.71241 -32.52042 1.000 18.37626 ? 9   PRO A N   1 
ATOM   50   C CA  . PRO A 1 8   ? -13.90337 21.67990 -33.04832 1.000 20.61243 ? 9   PRO A CA  1 
ATOM   51   C C   . PRO A 1 8   ? -14.04096 20.56852 -32.01296 1.000 22.30837 ? 9   PRO A C   1 
ATOM   52   O O   . PRO A 1 8   ? -13.06766 20.19166 -31.36371 1.000 20.97695 ? 9   PRO A O   1 
ATOM   53   C CB  . PRO A 1 8   ? -13.19459 21.20457 -34.32471 1.000 19.16390 ? 9   PRO A CB  1 
ATOM   54   C CG  . PRO A 1 8   ? -12.37453 22.41600 -34.74778 1.000 22.71197 ? 9   PRO A CG  1 
ATOM   55   C CD  . PRO A 1 8   ? -11.86214 22.96845 -33.42059 1.000 20.94168 ? 9   PRO A CD  1 
ATOM   56   N N   . SER A 1 9   ? -15.26275 20.08510 -31.81476 1.000 18.76119 ? 10  SER A N   1 
ATOM   57   C CA  . SER A 1 9   ? -15.54667 19.21919 -30.67204 1.000 22.05220 ? 10  SER A CA  1 
ATOM   58   C C   . SER A 1 9   ? -15.49203 17.72675 -30.99133 1.000 21.15680 ? 10  SER A C   1 
ATOM   59   O O   . SER A 1 9   ? -15.70375 16.91055 -30.08152 1.000 21.59179 ? 10  SER A O   1 
ATOM   60   C CB  . SER A 1 9   ? -16.92129 19.55817 -30.09092 1.000 25.45472 ? 10  SER A CB  1 
ATOM   61   O OG  . SER A 1 9   ? -17.92901 19.31213 -31.07004 1.000 24.32996 ? 10  SER A OG  1 
ATOM   62   N N   . GLY A 1 10  ? -15.21539 17.35330 -32.24337 1.000 19.56892 ? 11  GLY A N   1 
ATOM   63   C CA  . GLY A 1 10  ? -15.32915 15.95093 -32.63661 1.000 20.99543 ? 11  GLY A CA  1 
ATOM   64   C C   . GLY A 1 10  ? -14.46708 15.01778 -31.80393 1.000 23.33948 ? 11  GLY A C   1 
ATOM   65   O O   . GLY A 1 10  ? -14.92679 13.95070 -31.37625 1.000 22.23848 ? 11  GLY A O   1 
ATOM   66   N N   . ASP A 1 11  ? -13.21286 15.40757 -31.55269 1.000 20.20148 ? 12  ASP A N   1 
ATOM   67   C CA  . ASP A 1 11  ? -12.30740 14.54945 -30.78025 1.000 24.16424 ? 12  ASP A CA  1 
ATOM   68   C C   . ASP A 1 11  ? -12.89222 14.21550 -29.41528 1.000 23.83884 ? 12  ASP A C   1 
ATOM   69   O O   . ASP A 1 11  ? -12.71472 13.10128 -28.90876 1.000 24.73613 ? 12  ASP A O   1 
ATOM   70   C CB  . ASP A 1 11  ? -10.95296 15.23130 -30.56293 1.000 28.06912 ? 12  ASP A CB  1 
ATOM   71   C CG  . ASP A 1 11  ? -10.12747 15.37065 -31.82743 1.000 32.75519 ? 12  ASP A CG  1 
ATOM   72   O OD1 . ASP A 1 11  ? -10.28976 14.56247 -32.76698 1.000 37.40661 ? 12  ASP A OD1 1 
ATOM   73   O OD2 . ASP A 1 11  ? -9.31280  16.31775 -31.86665 1.000 41.47467 ? 12  ASP A OD2 1 
ATOM   74   N N   . VAL A 1 12  ? -13.53165 15.19475 -28.77356 1.000 17.64396 ? 13  VAL A N   1 
ATOM   75   C CA  . VAL A 1 12  ? -14.05283 14.98614 -27.43072 1.000 19.33857 ? 13  VAL A CA  1 
ATOM   76   C C   . VAL A 1 12  ? -15.40988 14.28854 -27.46764 1.000 21.65075 ? 13  VAL A C   1 
ATOM   77   O O   . VAL A 1 12  ? -15.73048 13.47855 -26.58450 1.000 18.64261 ? 13  VAL A O   1 
ATOM   78   C CB  . VAL A 1 12  ? -14.11861 16.33737 -26.69686 1.000 21.32407 ? 13  VAL A CB  1 
ATOM   79   C CG1 . VAL A 1 12  ? -14.86159 16.18834 -25.38192 1.000 19.43434 ? 13  VAL A CG1 1 
ATOM   80   C CG2 . VAL A 1 12  ? -12.70793 16.87350 -26.48031 1.000 20.56674 ? 13  VAL A CG2 1 
ATOM   81   N N   . GLU A 1 13  ? -16.23320 14.59462 -28.47460 1.000 18.89279 ? 14  GLU A N   1 
ATOM   82   C CA  . GLU A 1 13  ? -17.50699 13.89094 -28.63809 1.000 18.73687 ? 14  GLU A CA  1 
ATOM   83   C C   . GLU A 1 13  ? -17.32083 12.37866 -28.60771 1.000 21.64543 ? 14  GLU A C   1 
ATOM   84   O O   . GLU A 1 13  ? -18.11068 11.65693 -27.97980 1.000 19.86356 ? 14  GLU A O   1 
ATOM   85   C CB  . GLU A 1 13  ? -18.16559 14.29975 -29.96129 1.000 19.33195 ? 14  GLU A CB  1 
ATOM   86   C CG  . GLU A 1 13  ? -18.63330 15.74857 -30.01159 1.000 19.53903 ? 14  GLU A CG  1 
ATOM   87   C CD  . GLU A 1 13  ? -19.14077 16.12438 -31.40775 1.000 25.03013 ? 14  GLU A CD  1 
ATOM   88   O OE1 . GLU A 1 13  ? -19.92974 15.33946 -31.97661 1.000 22.27764 ? 14  GLU A OE1 1 
ATOM   89   O OE2 . GLU A 1 13  ? -18.75238 17.19594 -31.92341 1.000 25.88911 ? 14  GLU A OE2 1 
ATOM   90   N N   . ALA A 1 14  ? -16.27660 11.88324 -29.27772 1.000 19.97664 ? 15  ALA A N   1 
ATOM   91   C CA  . ALA A 1 14  ? -16.03639 10.44703 -29.35042 1.000 19.85328 ? 15  ALA A CA  1 
ATOM   92   C C   . ALA A 1 14  ? -15.67416 9.83443  -28.00228 1.000 22.79494 ? 15  ALA A C   1 
ATOM   93   O O   . ALA A 1 14  ? -15.57581 8.60997  -27.91241 1.000 23.61578 ? 15  ALA A O   1 
ATOM   94   C CB  . ALA A 1 14  ? -14.91762 10.15386 -30.36664 1.000 24.01332 ? 15  ALA A CB  1 
ATOM   95   N N   . CYS A 1 15  ? -15.48084 10.64671 -26.96799 1.000 18.74704 ? 16  CYS A N   1 
ATOM   96   C CA  . CYS A 1 15  ? -15.11975 10.18103 -25.63593 1.000 20.19690 ? 16  CYS A CA  1 
ATOM   97   C C   . CYS A 1 15  ? -16.26575 10.24124 -24.63072 1.000 20.44179 ? 16  CYS A C   1 
ATOM   98   O O   . CYS A 1 15  ? -16.10535 9.77898  -23.49843 1.000 20.60477 ? 16  CYS A O   1 
ATOM   99   C CB  . CYS A 1 15  ? -13.93830 11.01554 -25.11639 1.000 20.75350 ? 16  CYS A CB  1 
ATOM   100  S SG  . CYS A 1 15  ? -12.44553 10.80510 -26.13037 1.000 22.81457 ? 16  CYS A SG  1 
ATOM   101  N N   . MET A 1 16  ? -17.40443 10.80724 -24.99534 1.000 19.39806 ? 17  MET A N   1 
ATOM   102  C CA  . MET A 1 16  ? -18.46332 11.04220 -24.02120 1.000 19.08909 ? 17  MET A CA  1 
ATOM   103  C C   . MET A 1 16  ? -19.28129 9.76427  -23.83501 1.000 20.93887 ? 17  MET A C   1 
ATOM   104  O O   . MET A 1 16  ? -19.61381 9.07726  -24.80427 1.000 20.55935 ? 17  MET A O   1 
ATOM   105  C CB  . MET A 1 16  ? -19.36112 12.19130 -24.47182 1.000 22.72007 ? 17  MET A CB  1 
ATOM   106  C CG  . MET A 1 16  ? -18.65858 13.55688 -24.53045 1.000 20.04943 ? 17  MET A CG  1 
ATOM   107  S SD  . MET A 1 16  ? -17.60772 13.92302 -23.11219 1.000 23.36659 ? 17  MET A SD  1 
ATOM   108  C CE  . MET A 1 16  ? -18.74632 13.83654 -21.73786 1.000 20.82007 ? 17  MET A CE  1 
ATOM   109  N N   . VAL A 1 17  ? -19.55203 9.42000  -22.58269 1.000 19.20983 ? 18  VAL A N   1 
ATOM   110  C CA  . VAL A 1 17  ? -20.38582 8.27466  -22.24129 1.000 21.76457 ? 18  VAL A CA  1 
ATOM   111  C C   . VAL A 1 17  ? -21.39108 8.73396  -21.19277 1.000 24.30158 ? 18  VAL A C   1 
ATOM   112  O O   . VAL A 1 17  ? -21.28760 9.83248  -20.63580 1.000 21.79233 ? 18  VAL A O   1 
ATOM   113  C CB  . VAL A 1 17  ? -19.55746 7.07412  -21.72841 1.000 19.83488 ? 18  VAL A CB  1 
ATOM   114  C CG1 . VAL A 1 17  ? -18.59703 6.60829  -22.80412 1.000 23.93041 ? 18  VAL A CG1 1 
ATOM   115  C CG2 . VAL A 1 17  ? -18.78905 7.44734  -20.46130 1.000 19.94901 ? 18  VAL A CG2 1 
ATOM   116  N N   . GLN A 1 18  ? -22.39435 7.88905  -20.95189 1.000 24.19793 ? 19  GLN A N   1 
ATOM   117  C CA  . GLN A 1 18  ? -23.35636 8.09098  -19.87319 1.000 23.22814 ? 19  GLN A CA  1 
ATOM   118  C C   . GLN A 1 18  ? -23.01184 7.13447  -18.74097 1.000 21.56324 ? 19  GLN A C   1 
ATOM   119  O O   . GLN A 1 18  ? -22.74825 5.95250  -18.98545 1.000 23.99166 ? 19  GLN A O   1 
ATOM   120  C CB  . GLN A 1 18  ? -24.80328 7.85018  -20.34377 1.000 23.83197 ? 19  GLN A CB  1 
ATOM   121  C CG  . GLN A 1 18  ? -25.86304 7.88844  -19.20107 1.000 26.33463 ? 19  GLN A CG  1 
ATOM   122  C CD  . GLN A 1 18  ? -27.30750 8.01307  -19.72201 1.000 31.64954 ? 19  GLN A CD  1 
ATOM   123  O OE1 . GLN A 1 18  ? -27.60406 7.65080  -20.85273 1.000 35.55878 ? 19  GLN A OE1 1 
ATOM   124  N NE2 . GLN A 1 18  ? -28.19453 8.55102  -18.89461 1.000 29.43195 ? 19  GLN A NE2 1 
ATOM   125  N N   . VAL A 1 19  ? -22.96627 7.65378  -17.51853 1.000 20.75854 ? 20  VAL A N   1 
ATOM   126  C CA  . VAL A 1 19  ? -22.65916 6.86177  -16.33370 1.000 21.54886 ? 20  VAL A CA  1 
ATOM   127  C C   . VAL A 1 19  ? -23.87215 6.91212  -15.42326 1.000 22.03430 ? 20  VAL A C   1 
ATOM   128  O O   . VAL A 1 19  ? -24.35385 7.99940  -15.09098 1.000 21.99355 ? 20  VAL A O   1 
ATOM   129  C CB  . VAL A 1 19  ? -21.41875 7.38788  -15.58799 1.000 23.61756 ? 20  VAL A CB  1 
ATOM   130  C CG1 . VAL A 1 19  ? -21.14577 6.53560  -14.34816 1.000 25.11792 ? 20  VAL A CG1 1 
ATOM   131  C CG2 . VAL A 1 19  ? -20.21107 7.43266  -16.50665 1.000 22.54256 ? 20  VAL A CG2 1 
ATOM   132  N N   . THR A 1 20  ? -24.35240 5.74167  -14.99762 1.000 26.86240 ? 21  THR A N   1 
ATOM   133  C CA  . THR A 1 20  ? -25.45562 5.67734  -14.05276 1.000 29.10596 ? 21  THR A CA  1 
ATOM   134  C C   . THR A 1 20  ? -25.04001 4.87623  -12.82398 1.000 28.96727 ? 21  THR A C   1 
ATOM   135  O O   . THR A 1 20  ? -24.30795 3.88987  -12.92694 1.000 29.99430 ? 21  THR A O   1 
ATOM   136  C CB  . THR A 1 20  ? -26.71441 5.06091  -14.68512 1.000 27.20826 ? 21  THR A CB  1 
ATOM   137  O OG1 . THR A 1 20  ? -26.50421 3.66172  -14.89825 1.000 41.59720 ? 21  THR A OG1 1 
ATOM   138  C CG2 . THR A 1 20  ? -27.04222 5.71548  -16.01166 1.000 25.17910 ? 21  THR A CG2 1 
ATOM   139  N N   . CYS A 1 21  ? -25.48835 5.33060  -11.65844 1.000 28.82836 ? 22  CYS A N   1 
ATOM   140  C CA  . CYS A 1 21  ? -25.23901 4.63201  -10.39989 1.000 29.39889 ? 22  CYS A CA  1 
ATOM   141  C C   . CYS A 1 21  ? -26.48888 4.84687  -9.55969  1.000 31.53476 ? 22  CYS A C   1 
ATOM   142  O O   . CYS A 1 21  ? -26.82024 5.99052  -9.21420  1.000 29.20508 ? 22  CYS A O   1 
ATOM   143  C CB  . CYS A 1 21  ? -23.98150 5.15296  -9.70034  1.000 25.88775 ? 22  CYS A CB  1 
ATOM   144  S SG  . CYS A 1 21  ? -23.61643 4.44196  -8.04439  1.000 33.48362 ? 22  CYS A SG  1 
ATOM   145  N N   . GLY A 1 22  ? -27.21048 3.76753  -9.29185  1.000 33.58055 ? 23  GLY A N   1 
ATOM   146  C CA  . GLY A 1 22  ? -28.48215 3.89461  -8.59588  1.000 31.14010 ? 23  GLY A CA  1 
ATOM   147  C C   . GLY A 1 22  ? -29.42670 4.78925  -9.37263  1.000 33.09966 ? 23  GLY A C   1 
ATOM   148  O O   . GLY A 1 22  ? -29.69945 4.57433  -10.56542 1.000 34.50656 ? 23  GLY A O   1 
ATOM   149  N N   . SER A 1 23  ? -29.90699 5.83671  -8.70834  1.000 32.71293 ? 24  SER A N   1 
ATOM   150  C CA  . SER A 1 23  ? -30.85137 6.76919  -9.29940  1.000 34.54020 ? 24  SER A CA  1 
ATOM   151  C C   . SER A 1 23  ? -30.17145 7.98343  -9.92045  1.000 36.77515 ? 24  SER A C   1 
ATOM   152  O O   . SER A 1 23  ? -30.86439 8.90593  -10.36144 1.000 38.16966 ? 24  SER A O   1 
ATOM   153  C CB  . SER A 1 23  ? -31.85890 7.22756  -8.24534  1.000 37.21992 ? 24  SER A CB  1 
ATOM   154  O OG  . SER A 1 23  ? -31.17691 7.85605  -7.17427  1.000 43.34688 ? 24  SER A OG  1 
ATOM   155  N N   . MET A 1 24  ? -28.84343 8.00437  -9.97128  1.000 28.61855 ? 25  MET A N   1 
ATOM   156  C CA  . MET A 1 24  ? -28.10020 9.13327  -10.51504 1.000 30.22221 ? 25  MET A CA  1 
ATOM   157  C C   . MET A 1 24  ? -27.58341 8.79453  -11.90384 1.000 30.18517 ? 25  MET A C   1 
ATOM   158  O O   . MET A 1 24  ? -27.07937 7.69440  -12.13153 1.000 30.06905 ? 25  MET A O   1 
ATOM   159  C CB  . MET A 1 24  ? -26.92420 9.50054  -9.60560  1.000 30.73828 ? 25  MET A CB  1 
ATOM   160  C CG  . MET A 1 24  ? -27.32862 10.09071 -8.26898  1.000 33.90308 ? 25  MET A CG  1 
ATOM   161  S SD  . MET A 1 24  ? -28.10365 11.71951 -8.39657  1.000 39.01185 ? 25  MET A SD  1 
ATOM   162  C CE  . MET A 1 24  ? -27.47700 12.45671 -6.88712  1.000 40.78062 ? 25  MET A CE  1 
ATOM   163  N N   . THR A 1 25  ? -27.70583 9.74575  -12.82748 1.000 29.07049 ? 26  THR A N   1 
ATOM   164  C CA  . THR A 1 25  ? -27.19204 9.58305  -14.18099 1.000 24.92188 ? 26  THR A CA  1 
ATOM   165  C C   . THR A 1 25  ? -26.54455 10.88839 -14.63352 1.000 28.70003 ? 26  THR A C   1 
ATOM   166  O O   . THR A 1 25  ? -27.09503 11.97734 -14.41958 1.000 25.51777 ? 26  THR A O   1 
ATOM   167  C CB  . THR A 1 25  ? -28.30879 9.15658  -15.15480 1.000 25.85231 ? 26  THR A CB  1 
ATOM   168  O OG1 . THR A 1 25  ? -27.74121 8.82318  -16.43007 1.000 31.98535 ? 26  THR A OG1 1 
ATOM   169  C CG2 . THR A 1 25  ? -29.32999 10.25297 -15.33212 1.000 27.99349 ? 26  THR A CG2 1 
ATOM   170  N N   . LEU A 1 26  ? -25.36639 10.77733 -15.24705 1.000 24.69112 ? 27  LEU A N   1 
ATOM   171  C CA  . LEU A 1 26  ? -24.66036 11.95554 -15.73875 1.000 23.93377 ? 27  LEU A CA  1 
ATOM   172  C C   . LEU A 1 26  ? -23.68207 11.51187 -16.82769 1.000 23.50543 ? 27  LEU A C   1 
ATOM   173  O O   . LEU A 1 26  ? -23.75788 10.38592 -17.32839 1.000 24.23495 ? 27  LEU A O   1 
ATOM   174  C CB  . LEU A 1 26  ? -23.98345 12.70208 -14.58342 1.000 21.53537 ? 27  LEU A CB  1 
ATOM   175  C CG  . LEU A 1 26  ? -23.16232 11.89334 -13.57396 1.000 24.20464 ? 27  LEU A CG  1 
ATOM   176  C CD1 . LEU A 1 26  ? -21.83018 11.38296 -14.14864 1.000 25.42187 ? 27  LEU A CD1 1 
ATOM   177  C CD2 . LEU A 1 26  ? -22.89692 12.74781 -12.35285 1.000 22.86178 ? 27  LEU A CD2 1 
ATOM   178  N N   . ASN A 1 27  ? -22.77694 12.41368 -17.21606 1.000 21.48107 ? 28  ASN A N   1 
ATOM   179  C CA  . ASN A 1 27  ? -21.82014 12.15819 -18.27923 1.000 19.24583 ? 28  ASN A CA  1 
ATOM   180  C C   . ASN A 1 27  ? -20.47774 11.72387 -17.71599 1.000 17.62984 ? 28  ASN A C   1 
ATOM   181  O O   . ASN A 1 27  ? -20.10135 12.09778 -16.60457 1.000 20.99828 ? 28  ASN A O   1 
ATOM   182  C CB  . ASN A 1 27  ? -21.62618 13.40658 -19.14984 1.000 19.94984 ? 28  ASN A CB  1 
ATOM   183  C CG  . ASN A 1 27  ? -22.95651 13.98308 -19.64614 1.000 20.55734 ? 28  ASN A CG  1 
ATOM   184  O OD1 . ASN A 1 27  ? -23.56211 13.45477 -20.57237 1.000 24.43622 ? 28  ASN A OD1 1 
ATOM   185  N ND2 . ASN A 1 27  ? -23.41291 15.06211 -19.01539 1.000 22.39045 ? 28  ASN A ND2 1 
ATOM   186  N N   . GLY A 1 28  ? -19.75192 10.93536 -18.50935 1.000 22.80115 ? 29  GLY A N   1 
ATOM   187  C CA  . GLY A 1 28  ? -18.38495 10.58417 -18.18938 1.000 23.12645 ? 29  GLY A CA  1 
ATOM   188  C C   . GLY A 1 28  ? -17.50265 10.73020 -19.40805 1.000 21.81306 ? 29  GLY A C   1 
ATOM   189  O O   . GLY A 1 28  ? -17.97593 10.79713 -20.54284 1.000 21.67513 ? 29  GLY A O   1 
ATOM   190  N N   . LEU A 1 29  ? -16.19205 10.77778 -19.16310 1.000 18.13146 ? 30  LEU A N   1 
ATOM   191  C CA  . LEU A 1 29  ? -15.17560 10.90818 -20.20488 1.000 18.26422 ? 30  LEU A CA  1 
ATOM   192  C C   . LEU A 1 29  ? -14.39162 9.60693  -20.28472 1.000 19.46643 ? 30  LEU A C   1 
ATOM   193  O O   . LEU A 1 29  ? -13.72793 9.22251  -19.31880 1.000 20.18422 ? 30  LEU A O   1 
ATOM   194  C CB  . LEU A 1 29  ? -14.21875 12.06764 -19.92211 1.000 16.15099 ? 30  LEU A CB  1 
ATOM   195  C CG  . LEU A 1 29  ? -13.20860 12.38139 -21.02747 1.000 18.10395 ? 30  LEU A CG  1 
ATOM   196  C CD1 . LEU A 1 29  ? -13.88831 13.02704 -22.22744 1.000 16.82280 ? 30  LEU A CD1 1 
ATOM   197  C CD2 . LEU A 1 29  ? -12.13325 13.30068 -20.49933 1.000 17.32644 ? 30  LEU A CD2 1 
ATOM   198  N N   . TRP A 1 30  ? -14.45082 8.96186  -21.43254 1.000 18.30859 ? 31  TRP A N   1 
ATOM   199  C CA  . TRP A 1 30  ? -13.81970 7.66335  -21.66529 1.000 19.92558 ? 31  TRP A CA  1 
ATOM   200  C C   . TRP A 1 30  ? -12.48676 7.87850  -22.37164 1.000 18.69525 ? 31  TRP A C   1 
ATOM   201  O O   . TRP A 1 30  ? -12.45031 8.20484  -23.56398 1.000 19.90669 ? 31  TRP A O   1 
ATOM   202  C CB  . TRP A 1 30  ? -14.75251 6.80140  -22.50771 1.000 16.47254 ? 31  TRP A CB  1 
ATOM   203  C CG  . TRP A 1 30  ? -14.30218 5.39096  -22.77952 1.000 22.29530 ? 31  TRP A CG  1 
ATOM   204  C CD1 . TRP A 1 30  ? -13.37262 4.65334  -22.07604 1.000 20.49983 ? 31  TRP A CD1 1 
ATOM   205  C CD2 . TRP A 1 30  ? -14.78052 4.54201  -23.83026 1.000 23.72899 ? 31  TRP A CD2 1 
ATOM   206  N NE1 . TRP A 1 30  ? -13.25335 3.39698  -22.64193 1.000 21.79419 ? 31  TRP A NE1 1 
ATOM   207  C CE2 . TRP A 1 30  ? -14.09949 3.30772  -23.71839 1.000 23.89343 ? 31  TRP A CE2 1 
ATOM   208  C CE3 . TRP A 1 30  ? -15.70554 4.71428  -24.87369 1.000 22.94660 ? 31  TRP A CE3 1 
ATOM   209  C CZ2 . TRP A 1 30  ? -14.31984 2.25159  -24.60296 1.000 24.82356 ? 31  TRP A CZ2 1 
ATOM   210  C CZ3 . TRP A 1 30  ? -15.91300 3.66706  -25.75671 1.000 24.29528 ? 31  TRP A CZ3 1 
ATOM   211  C CH2 . TRP A 1 30  ? -15.22808 2.44952  -25.61326 1.000 27.13428 ? 31  TRP A CH2 1 
ATOM   212  N N   . LEU A 1 31  ? -11.39163 7.69500  -21.64641 1.000 18.16943 ? 32  LEU A N   1 
ATOM   213  C CA  . LEU A 1 31  ? -10.05629 7.78030  -22.22750 1.000 20.99154 ? 32  LEU A CA  1 
ATOM   214  C C   . LEU A 1 31  ? -9.34414  6.46065  -21.97973 1.000 20.95632 ? 32  LEU A C   1 
ATOM   215  O O   . LEU A 1 31  ? -9.16767  6.06719  -20.82273 1.000 18.87098 ? 32  LEU A O   1 
ATOM   216  C CB  . LEU A 1 31  ? -9.25940  8.93414  -21.61175 1.000 16.95126 ? 32  LEU A CB  1 
ATOM   217  C CG  . LEU A 1 31  ? -9.92120  10.30273 -21.66395 1.000 17.97247 ? 32  LEU A CG  1 
ATOM   218  C CD1 . LEU A 1 31  ? -9.10031  11.30490 -20.85599 1.000 16.67418 ? 32  LEU A CD1 1 
ATOM   219  C CD2 . LEU A 1 31  ? -10.02854 10.74079 -23.11634 1.000 17.49430 ? 32  LEU A CD2 1 
ATOM   220  N N   . ASP A 1 32  ? -8.93162  5.79029  -23.05967 1.000 20.46848 ? 33  ASP A N   1 
ATOM   221  C CA  . ASP A 1 32  ? -8.26994  4.49006  -22.96601 1.000 21.33404 ? 33  ASP A CA  1 
ATOM   222  C C   . ASP A 1 32  ? -9.13868  3.55519  -22.12795 1.000 22.40177 ? 33  ASP A C   1 
ATOM   223  O O   . ASP A 1 32  ? -10.30696 3.37181  -22.47458 1.000 19.66181 ? 33  ASP A O   1 
ATOM   224  C CB  . ASP A 1 32  ? -6.84366  4.67618  -22.42817 1.000 21.82227 ? 33  ASP A CB  1 
ATOM   225  C CG  . ASP A 1 32  ? -5.99428  5.51600  -23.37817 1.000 25.09350 ? 33  ASP A CG  1 
ATOM   226  O OD1 . ASP A 1 32  ? -6.11986  5.30869  -24.60612 1.000 25.55206 ? 33  ASP A OD1 1 
ATOM   227  O OD2 . ASP A 1 32  ? -5.25320  6.41051  -22.92048 1.000 25.37682 ? 33  ASP A OD2 1 
ATOM   228  N N   . ASN A 1 33  ? -8.62592  2.98403  -21.02656 1.000 20.86182 ? 34  ASN A N   1 
ATOM   229  C CA  . ASN A 1 33  ? -9.42510  2.06531  -20.20704 1.000 23.02744 ? 34  ASN A CA  1 
ATOM   230  C C   . ASN A 1 33  ? -10.06491 2.72684  -18.99474 1.000 22.91987 ? 34  ASN A C   1 
ATOM   231  O O   . ASN A 1 33  ? -10.48456 2.02493  -18.06198 1.000 24.89262 ? 34  ASN A O   1 
ATOM   232  C CB  . ASN A 1 33  ? -8.58295  0.87361  -19.73894 1.000 22.35663 ? 34  ASN A CB  1 
ATOM   233  C CG  . ASN A 1 33  ? -8.30631  -0.10066 -20.85539 1.000 21.50943 ? 34  ASN A CG  1 
ATOM   234  O OD1 . ASN A 1 33  ? -7.28541  0.00129  -21.53093 1.000 22.77591 ? 34  ASN A OD1 1 
ATOM   235  N ND2 . ASN A 1 33  ? -9.22341  -1.03890 -21.08113 1.000 20.75012 ? 34  ASN A ND2 1 
ATOM   236  N N   . THR A 1 34  ? -10.15333 4.05125  -18.97281 1.000 21.22147 ? 35  THR A N   1 
ATOM   237  C CA  . THR A 1 34  ? -10.66886 4.77749  -17.82416 1.000 19.47539 ? 35  THR A CA  1 
ATOM   238  C C   . THR A 1 34  ? -11.89861 5.59064  -18.22338 1.000 20.81902 ? 35  THR A C   1 
ATOM   239  O O   . THR A 1 34  ? -11.92259 6.22889  -19.28650 1.000 20.01583 ? 35  THR A O   1 
ATOM   240  C CB  . THR A 1 34  ? -9.58040  5.70269  -17.24066 1.000 22.62175 ? 35  THR A CB  1 
ATOM   241  O OG1 . THR A 1 34  ? -8.43776  4.92384  -16.85769 1.000 22.39863 ? 35  THR A OG1 1 
ATOM   242  C CG2 . THR A 1 34  ? -10.09026 6.43914  -16.02437 1.000 24.55372 ? 35  THR A CG2 1 
ATOM   243  N N   . VAL A 1 35  ? -12.92271 5.56447  -17.37794 1.000 21.37290 ? 36  VAL A N   1 
ATOM   244  C CA  . VAL A 1 35  ? -14.04632 6.49495  -17.48757 1.000 22.72463 ? 36  VAL A CA  1 
ATOM   245  C C   . VAL A 1 35  ? -14.02201 7.38535  -16.25519 1.000 19.45883 ? 36  VAL A C   1 
ATOM   246  O O   . VAL A 1 35  ? -14.08983 6.89397  -15.11772 1.000 22.62473 ? 36  VAL A O   1 
ATOM   247  C CB  . VAL A 1 35  ? -15.39838 5.77581  -17.63218 1.000 23.81757 ? 36  VAL A CB  1 
ATOM   248  C CG1 . VAL A 1 35  ? -16.55027 6.78140  -17.56256 1.000 19.94441 ? 36  VAL A CG1 1 
ATOM   249  C CG2 . VAL A 1 35  ? -15.45847 4.99102  -18.94155 1.000 23.12329 ? 36  VAL A CG2 1 
ATOM   250  N N   . TRP A 1 36  ? -13.90136 8.68999  -16.49078 1.000 20.51446 ? 37  TRP A N   1 
ATOM   251  C CA  . TRP A 1 36  ? -13.91628 9.73355  -15.47356 1.000 19.69855 ? 37  TRP A CA  1 
ATOM   252  C C   . TRP A 1 36  ? -15.31926 10.30062 -15.32457 1.000 22.36274 ? 37  TRP A C   1 
ATOM   253  O O   . TRP A 1 36  ? -15.98488 10.57844 -16.32249 1.000 23.74200 ? 37  TRP A O   1 
ATOM   254  C CB  . TRP A 1 36  ? -12.98647 10.87872 -15.88049 1.000 21.34701 ? 37  TRP A CB  1 
ATOM   255  C CG  . TRP A 1 36  ? -11.54157 10.48975 -15.97254 1.000 22.30443 ? 37  TRP A CG  1 
ATOM   256  C CD1 . TRP A 1 36  ? -10.85460 10.09935 -17.08059 1.000 22.95408 ? 37  TRP A CD1 1 
ATOM   257  C CD2 . TRP A 1 36  ? -10.62320 10.45530 -14.89196 1.000 21.55648 ? 37  TRP A CD2 1 
ATOM   258  N NE1 . TRP A 1 36  ? -9.54022  9.82286  -16.75134 1.000 21.39905 ? 37  TRP A NE1 1 
ATOM   259  C CE2 . TRP A 1 36  ? -9.37836  10.04829 -15.40873 1.000 23.98893 ? 37  TRP A CE2 1 
ATOM   260  C CE3 . TRP A 1 36  ? -10.72884 10.74437 -13.53012 1.000 24.70043 ? 37  TRP A CE3 1 
ATOM   261  C CZ2 . TRP A 1 36  ? -8.25186  9.90531  -14.60598 1.000 26.89943 ? 37  TRP A CZ2 1 
ATOM   262  C CZ3 . TRP A 1 36  ? -9.60863  10.60951 -12.73679 1.000 28.13928 ? 37  TRP A CZ3 1 
ATOM   263  C CH2 . TRP A 1 36  ? -8.38426  10.19330 -13.27990 1.000 27.21385 ? 37  TRP A CH2 1 
ATOM   264  N N   . CYS A 1 37  ? -15.75566 10.51917 -14.08692 1.000 20.84321 ? 38  CYS A N   1 
ATOM   265  C CA  . CYS A 1 37  ? -17.05003 11.15292 -13.88944 1.000 21.38983 ? 38  CYS A CA  1 
ATOM   266  C C   . CYS A 1 37  ? -17.09636 11.74394 -12.48405 1.000 22.94945 ? 38  CYS A C   1 
ATOM   267  O O   . CYS A 1 37  ? -16.27057 11.39268 -11.63494 1.000 22.90144 ? 38  CYS A O   1 
ATOM   268  C CB  . CYS A 1 37  ? -18.19132 10.15426 -14.12263 1.000 21.38399 ? 38  CYS A CB  1 
ATOM   269  S SG  . CYS A 1 37  ? -18.41685 8.96545  -12.78769 1.000 26.24619 ? 38  CYS A SG  1 
ATOM   270  N N   . PRO A 1 38  ? -18.02208 12.67379 -12.21860 1.000 22.50813 ? 39  PRO A N   1 
ATOM   271  C CA  . PRO A 1 38  ? -18.10416 13.25030 -10.86795 1.000 23.75364 ? 39  PRO A CA  1 
ATOM   272  C C   . PRO A 1 38  ? -18.46381 12.17584 -9.85211  1.000 22.72211 ? 39  PRO A C   1 
ATOM   273  O O   . PRO A 1 38  ? -19.27802 11.29602 -10.12105 1.000 21.45144 ? 39  PRO A O   1 
ATOM   274  C CB  . PRO A 1 38  ? -19.21168 14.30900 -10.98890 1.000 22.84749 ? 39  PRO A CB  1 
ATOM   275  C CG  . PRO A 1 38  ? -19.27286 14.63345 -12.47793 1.000 21.57788 ? 39  PRO A CG  1 
ATOM   276  C CD  . PRO A 1 38  ? -18.97960 13.30948 -13.15080 1.000 20.08732 ? 39  PRO A CD  1 
ATOM   277  N N   . ARG A 1 39  ? -17.83871 12.24741 -8.67826  1.000 22.58227 ? 40  ARG A N   1 
ATOM   278  C CA  . ARG A 1 39  ? -18.12563 11.23382 -7.67186  1.000 26.53145 ? 40  ARG A CA  1 
ATOM   279  C C   . ARG A 1 39  ? -19.54145 11.36264 -7.12234  1.000 28.05694 ? 40  ARG A C   1 
ATOM   280  O O   . ARG A 1 39  ? -20.05034 10.38924 -6.56069  1.000 27.92308 ? 40  ARG A O   1 
ATOM   281  C CB  . ARG A 1 39  ? -17.09583 11.28846 -6.53465  1.000 23.59017 ? 40  ARG A CB  1 
ATOM   282  C CG  . ARG A 1 39  ? -17.28380 12.43979 -5.55418  1.000 27.29092 ? 40  ARG A CG  1 
ATOM   283  C CD  . ARG A 1 39  ? -16.19117 12.46312 -4.46768  1.000 26.50114 ? 40  ARG A CD  1 
ATOM   284  N NE  . ARG A 1 39  ? -16.24293 13.70113 -3.68041  1.000 27.54045 ? 40  ARG A NE  1 
ATOM   285  C CZ  . ARG A 1 39  ? -15.58608 13.89694 -2.53560  1.000 29.43152 ? 40  ARG A CZ  1 
ATOM   286  N NH1 . ARG A 1 39  ? -14.81087 12.94371 -2.03663  1.000 26.47608 ? 40  ARG A NH1 1 
ATOM   287  N NH2 . ARG A 1 39  ? -15.68746 15.05513 -1.89945  1.000 27.93286 ? 40  ARG A NH2 1 
ATOM   288  N N   . HIS A 1 40  ? -20.20600 12.52059 -7.30419  1.000 27.12610 ? 41  HIS A N   1 
ATOM   289  C CA  . HIS A 1 40  ? -21.55341 12.64331 -6.75432  1.000 27.79825 ? 41  HIS A CA  1 
ATOM   290  C C   . HIS A 1 40  ? -22.58084 11.79154 -7.49561  1.000 29.29078 ? 41  HIS A C   1 
ATOM   291  O O   . HIS A 1 40  ? -23.73888 11.74269 -7.06266  1.000 29.33985 ? 41  HIS A O   1 
ATOM   292  C CB  . HIS A 1 40  ? -21.99361 14.12253 -6.65656  1.000 26.97421 ? 41  HIS A CB  1 
ATOM   293  C CG  . HIS A 1 40  ? -22.16059 14.85888 -7.96219  1.000 24.82424 ? 41  HIS A CG  1 
ATOM   294  N ND1 . HIS A 1 40  ? -23.03878 14.46965 -8.94962  1.000 27.97319 ? 41  HIS A ND1 1 
ATOM   295  C CD2 . HIS A 1 40  ? -21.61761 16.02617 -8.38725  1.000 26.44892 ? 41  HIS A CD2 1 
ATOM   296  C CE1 . HIS A 1 40  ? -23.00654 15.34712 -9.94072  1.000 28.24606 ? 41  HIS A CE1 1 
ATOM   297  N NE2 . HIS A 1 40  ? -22.15049 16.30158 -9.62352  1.000 27.23560 ? 41  HIS A NE2 1 
ATOM   298  N N   . VAL A 1 41  ? -22.17804 11.06367 -8.54249  1.000 23.02955 ? 42  VAL A N   1 
ATOM   299  C CA  . VAL A 1 41  ? -23.04025 10.02528 -9.10296  1.000 25.59714 ? 42  VAL A CA  1 
ATOM   300  C C   . VAL A 1 41  ? -23.34973 8.94838  -8.06758  1.000 28.78300 ? 42  VAL A C   1 
ATOM   301  O O   . VAL A 1 41  ? -24.33130 8.21624  -8.22129  1.000 25.74665 ? 42  VAL A O   1 
ATOM   302  C CB  . VAL A 1 41  ? -22.40349 9.39738  -10.36204 1.000 25.20156 ? 42  VAL A CB  1 
ATOM   303  C CG1 . VAL A 1 41  ? -21.36568 8.33424  -9.98726  1.000 25.99292 ? 42  VAL A CG1 1 
ATOM   304  C CG2 . VAL A 1 41  ? -23.48415 8.81094  -11.27255 1.000 27.82408 ? 42  VAL A CG2 1 
ATOM   305  N N   . MET A 1 42  ? -22.53666 8.83899  -7.01143  1.000 25.40561 ? 43  MET A N   1 
ATOM   306  C CA  . MET A 1 42  ? -22.73586 7.84553  -5.95741  1.000 27.56294 ? 43  MET A CA  1 
ATOM   307  C C   . MET A 1 42  ? -23.65898 8.32669  -4.85034  1.000 34.81080 ? 43  MET A C   1 
ATOM   308  O O   . MET A 1 42  ? -24.01472 7.53367  -3.96882  1.000 34.12598 ? 43  MET A O   1 
ATOM   309  C CB  . MET A 1 42  ? -21.39960 7.46098  -5.31564  1.000 27.24141 ? 43  MET A CB  1 
ATOM   310  C CG  . MET A 1 42  ? -20.42098 6.75844  -6.23239  1.000 29.09344 ? 43  MET A CG  1 
ATOM   311  S SD  . MET A 1 42  ? -19.01778 6.09569  -5.27805  1.000 31.96021 ? 43  MET A SD  1 
ATOM   312  C CE  . MET A 1 42  ? -18.38314 7.57683  -4.50852  1.000 31.64958 ? 43  MET A CE  1 
ATOM   313  N N   . CYS A 1 43  ? -24.02483 9.59319  -4.85329  1.000 34.17718 ? 44  CYS A N   1 
ATOM   314  C CA  . CYS A 1 43  ? -24.75535 10.16039 -3.72508  1.000 39.76690 ? 44  CYS A CA  1 
ATOM   315  C C   . CYS A 1 43  ? -26.21968 9.72749  -3.76707  1.000 43.33172 ? 44  CYS A C   1 
ATOM   316  O O   . CYS A 1 43  ? -26.87192 9.87036  -4.80665  1.000 41.03988 ? 44  CYS A O   1 
ATOM   317  C CB  . CYS A 1 43  ? -24.65385 11.68312 -3.74212  1.000 38.58828 ? 44  CYS A CB  1 
ATOM   318  S SG  . CYS A 1 43  ? -25.33479 12.46158 -2.26682  1.000 44.12552 ? 44  CYS A SG  1 
ATOM   319  N N   . PRO A 1 44  ? -26.76628 9.20164  -2.66990  1.000 45.96598 ? 45  PRO A N   1 
ATOM   320  C CA  . PRO A 1 44  ? -28.19246 8.85421  -2.65321  1.000 48.65325 ? 45  PRO A CA  1 
ATOM   321  C C   . PRO A 1 44  ? -29.06287 10.10162 -2.64754  1.000 48.98915 ? 45  PRO A C   1 
ATOM   322  O O   . PRO A 1 44  ? -28.65468 11.17093 -2.18787  1.000 47.03407 ? 45  PRO A O   1 
ATOM   323  C CB  . PRO A 1 44  ? -28.35486 8.06229  -1.34754  1.000 53.57225 ? 45  PRO A CB  1 
ATOM   324  C CG  . PRO A 1 44  ? -26.95190 7.82868  -0.82774  1.000 52.43626 ? 45  PRO A CG  1 
ATOM   325  C CD  . PRO A 1 44  ? -26.11871 8.93332  -1.37702  1.000 46.00042 ? 45  PRO A CD  1 
ATOM   326  N N   . ALA A 1 45  ? -30.28608 9.95539  -3.16239  1.000 48.68430 ? 46  ALA A N   1 
ATOM   327  C CA  . ALA A 1 45  ? -31.19292 11.09593 -3.20914  1.000 54.10641 ? 46  ALA A CA  1 
ATOM   328  C C   . ALA A 1 45  ? -31.54592 11.60403 -1.81658  1.000 54.88798 ? 46  ALA A C   1 
ATOM   329  O O   . ALA A 1 45  ? -31.94000 12.76545 -1.67538  1.000 56.00132 ? 46  ALA A O   1 
ATOM   330  C CB  . ALA A 1 45  ? -32.46206 10.73105 -3.98111  1.000 51.51326 ? 46  ALA A CB  1 
ATOM   331  N N   . ASP A 1 46  ? -31.38187 10.77492 -0.78622  1.000 57.92912 ? 47  ASP A N   1 
ATOM   332  C CA  . ASP A 1 46  ? -31.72767 11.13200 0.58246   1.000 60.09437 ? 47  ASP A CA  1 
ATOM   333  C C   . ASP A 1 46  ? -30.55787 11.70332 1.37694   1.000 60.82519 ? 47  ASP A C   1 
ATOM   334  O O   . ASP A 1 46  ? -30.75003 12.09528 2.53102   1.000 62.13917 ? 47  ASP A O   1 
ATOM   335  C CB  . ASP A 1 46  ? -32.29563 9.90528  1.31504   1.000 63.05482 ? 47  ASP A CB  1 
ATOM   336  C CG  . ASP A 1 46  ? -31.30385 8.75562  1.39681   1.000 65.68076 ? 47  ASP A CG  1 
ATOM   337  O OD1 . ASP A 1 46  ? -30.64027 8.60674  2.44735   1.000 67.71545 ? 47  ASP A OD1 1 
ATOM   338  O OD2 . ASP A 1 46  ? -31.19043 7.99123  0.41664   1.000 67.16446 ? 47  ASP A OD2 1 
ATOM   339  N N   . GLN A 1 47  ? -29.35599 11.75858 0.80477   1.000 53.87754 ? 48  GLN A N   1 
ATOM   340  C CA  . GLN A 1 47  ? -28.18765 12.26130 1.51976   1.000 55.83822 ? 48  GLN A CA  1 
ATOM   341  C C   . GLN A 1 47  ? -27.49295 13.36874 0.73142   1.000 49.82389 ? 48  GLN A C   1 
ATOM   342  O O   . GLN A 1 47  ? -26.27110 13.52631 0.81602   1.000 48.29273 ? 48  GLN A O   1 
ATOM   343  C CB  . GLN A 1 47  ? -27.20390 11.13039 1.82424   1.000 57.02907 ? 48  GLN A CB  1 
ATOM   344  C CG  . GLN A 1 47  ? -27.73753 10.03039 2.72932   1.000 60.94755 ? 48  GLN A CG  1 
ATOM   345  C CD  . GLN A 1 47  ? -26.90103 8.76336  2.64714   1.000 62.31759 ? 48  GLN A CD  1 
ATOM   346  O OE1 . GLN A 1 47  ? -25.70618 8.81216  2.34702   1.000 62.46131 ? 48  GLN A OE1 1 
ATOM   347  N NE2 . GLN A 1 47  ? -27.52822 7.62020  2.90478   1.000 63.69079 ? 48  GLN A NE2 1 
ATOM   348  N N   . LEU A 1 48  ? -28.26452 14.14158 -0.03678  1.000 45.22366 ? 49  LEU A N   1 
ATOM   349  C CA  . LEU A 1 48  ? -27.69160 15.20500 -0.85525  1.000 48.42942 ? 49  LEU A CA  1 
ATOM   350  C C   . LEU A 1 48  ? -26.87083 16.18687 -0.02712  1.000 48.40506 ? 49  LEU A C   1 
ATOM   351  O O   . LEU A 1 48  ? -25.85446 16.70347 -0.50690  1.000 45.16366 ? 49  LEU A O   1 
ATOM   352  C CB  . LEU A 1 48  ? -28.80269 15.95091 -1.60095  1.000 46.14786 ? 49  LEU A CB  1 
ATOM   353  C CG  . LEU A 1 48  ? -29.67555 15.15586 -2.57602  1.000 49.19161 ? 49  LEU A CG  1 
ATOM   354  C CD1 . LEU A 1 48  ? -30.56650 16.09405 -3.36439  1.000 48.48592 ? 49  LEU A CD1 1 
ATOM   355  C CD2 . LEU A 1 48  ? -28.82679 14.31996 -3.51407  1.000 44.18576 ? 49  LEU A CD2 1 
ATOM   356  N N   . SER A 1 49  ? -27.28023 16.45327 1.21354   1.000 45.46377 ? 50  SER A N   1 
ATOM   357  C CA  . SER A 1 49  ? -26.63846 17.50176 1.99356   1.000 47.36321 ? 50  SER A CA  1 
ATOM   358  C C   . SER A 1 49  ? -25.43806 17.02075 2.79814   1.000 49.98334 ? 50  SER A C   1 
ATOM   359  O O   . SER A 1 49  ? -24.65004 17.85574 3.26010   1.000 49.02947 ? 50  SER A O   1 
ATOM   360  C CB  . SER A 1 49  ? -27.65147 18.15264 2.93559   1.000 47.66317 ? 50  SER A CB  1 
ATOM   361  O OG  . SER A 1 49  ? -28.34882 17.16102 3.65489   1.000 52.55165 ? 50  SER A OG  1 
ATOM   362  N N   . ASP A 1 50  ? -25.25923 15.71505 2.96969   1.000 48.85730 ? 51  ASP A N   1 
ATOM   363  C CA  . ASP A 1 50  ? -24.10112 15.30253 3.75269   1.000 50.76845 ? 51  ASP A CA  1 
ATOM   364  C C   . ASP A 1 50  ? -23.59805 13.91850 3.36521   1.000 50.97531 ? 51  ASP A C   1 
ATOM   365  O O   . ASP A 1 50  ? -23.52563 13.02794 4.22325   1.000 51.32208 ? 51  ASP A O   1 
ATOM   366  C CB  . ASP A 1 50  ? -24.44077 15.32977 5.24350   1.000 57.75659 ? 51  ASP A CB  1 
ATOM   367  C CG  . ASP A 1 50  ? -23.21232 15.48805 6.11350   1.000 60.86176 ? 51  ASP A CG  1 
ATOM   368  O OD1 . ASP A 1 50  ? -22.51880 16.52079 5.97577   1.000 63.57481 ? 51  ASP A OD1 1 
ATOM   369  O OD2 . ASP A 1 50  ? -22.94114 14.58229 6.92872   1.000 61.24976 ? 51  ASP A OD2 1 
ATOM   370  N N   . PRO A 1 51  ? -23.21826 13.69587 2.10779   1.000 50.56648 ? 52  PRO A N   1 
ATOM   371  C CA  . PRO A 1 51  ? -22.74427 12.36362 1.72349   1.000 47.64499 ? 52  PRO A CA  1 
ATOM   372  C C   . PRO A 1 51  ? -21.36125 12.10805 2.28945   1.000 46.85001 ? 52  PRO A C   1 
ATOM   373  O O   . PRO A 1 51  ? -20.54944 13.02472 2.44950   1.000 49.29404 ? 52  PRO A O   1 
ATOM   374  C CB  . PRO A 1 51  ? -22.72344 12.41664 0.19036   1.000 44.08358 ? 52  PRO A CB  1 
ATOM   375  C CG  . PRO A 1 51  ? -22.46964 13.86654 -0.12236  1.000 44.63908 ? 52  PRO A CG  1 
ATOM   376  C CD  . PRO A 1 51  ? -23.07279 14.67703 1.01117   1.000 46.83602 ? 52  PRO A CD  1 
ATOM   377  N N   . ASN A 1 52  ? -21.10784 10.84792 2.62547   1.000 43.25757 ? 53  ASN A N   1 
ATOM   378  C CA  . ASN A 1 52  ? -19.78146 10.40781 3.04547   1.000 43.02898 ? 53  ASN A CA  1 
ATOM   379  C C   . ASN A 1 52  ? -19.23778 9.60556  1.87633   1.000 40.57142 ? 53  ASN A C   1 
ATOM   380  O O   . ASN A 1 52  ? -19.61665 8.44655  1.67673   1.000 40.40369 ? 53  ASN A O   1 
ATOM   381  C CB  . ASN A 1 52  ? -19.82648 9.58418  4.32975   1.000 46.53086 ? 53  ASN A CB  1 
ATOM   382  C CG  . ASN A 1 52  ? -18.44221 9.19722  4.81778   1.000 45.25123 ? 53  ASN A CG  1 
ATOM   383  O OD1 . ASN A 1 52  ? -17.45058 9.38108  4.11401   1.000 49.84175 ? 53  ASN A OD1 1 
ATOM   384  N ND2 . ASN A 1 52  ? -18.36819 8.65958  6.03031   1.000 48.00213 ? 53  ASN A ND2 1 
ATOM   385  N N   . TYR A 1 53  ? -18.35625 10.23408 1.09730   1.000 42.34377 ? 54  TYR A N   1 
ATOM   386  C CA  . TYR A 1 53  ? -17.93393 9.62299  -0.15717  1.000 40.02683 ? 54  TYR A CA  1 
ATOM   387  C C   . TYR A 1 53  ? -16.99399 8.45131  0.07940   1.000 38.64920 ? 54  TYR A C   1 
ATOM   388  O O   . TYR A 1 53  ? -16.99922 7.48865  -0.69732  1.000 34.77665 ? 54  TYR A O   1 
ATOM   389  C CB  . TYR A 1 53  ? -17.29812 10.68507 -1.05821  1.000 33.63505 ? 54  TYR A CB  1 
ATOM   390  C CG  . TYR A 1 53  ? -18.33896 11.56955 -1.70293  1.000 33.37005 ? 54  TYR A CG  1 
ATOM   391  C CD1 . TYR A 1 53  ? -19.26565 11.03891 -2.59648  1.000 32.55907 ? 54  TYR A CD1 1 
ATOM   392  C CD2 . TYR A 1 53  ? -18.41472 12.92529 -1.40473  1.000 30.72851 ? 54  TYR A CD2 1 
ATOM   393  C CE1 . TYR A 1 53  ? -20.23095 11.83128 -3.18443  1.000 31.65605 ? 54  TYR A CE1 1 
ATOM   394  C CE2 . TYR A 1 53  ? -19.37747 13.73381 -1.99902  1.000 33.98453 ? 54  TYR A CE2 1 
ATOM   395  C CZ  . TYR A 1 53  ? -20.28122 13.17861 -2.88032  1.000 31.54180 ? 54  TYR A CZ  1 
ATOM   396  O OH  . TYR A 1 53  ? -21.23988 13.95718 -3.47469  1.000 34.24031 ? 54  TYR A OH  1 
ATOM   397  N N   . ASP A 1 54  ? -16.18925 8.50930  1.14245   1.000 43.90288 ? 55  ASP A N   1 
ATOM   398  C CA  . ASP A 1 54  ? -15.39075 7.35064  1.52543   1.000 41.75863 ? 55  ASP A CA  1 
ATOM   399  C C   . ASP A 1 54  ? -16.28482 6.15264  1.80991   1.000 40.92927 ? 55  ASP A C   1 
ATOM   400  O O   . ASP A 1 54  ? -16.04241 5.04951  1.31296   1.000 40.63660 ? 55  ASP A O   1 
ATOM   401  C CB  . ASP A 1 54  ? -14.53587 7.68745  2.74648   1.000 48.48301 ? 55  ASP A CB  1 
ATOM   402  C CG  . ASP A 1 54  ? -13.83077 9.01710  2.61075   1.000 52.98887 ? 55  ASP A CG  1 
ATOM   403  O OD1 . ASP A 1 54  ? -12.75250 9.04523  1.97805   1.000 55.97341 ? 55  ASP A OD1 1 
ATOM   404  O OD2 . ASP A 1 54  ? -14.35995 10.03310 3.12263   1.000 57.87180 ? 55  ASP A OD2 1 
ATOM   405  N N   . ALA A 1 55  ? -17.34341 6.36213  2.59414   1.000 43.80038 ? 56  ALA A N   1 
ATOM   406  C CA  . ALA A 1 55  ? -18.27758 5.28110  2.88512   1.000 43.91216 ? 56  ALA A CA  1 
ATOM   407  C C   . ALA A 1 55  ? -18.95361 4.78385  1.61688   1.000 43.42588 ? 56  ALA A C   1 
ATOM   408  O O   . ALA A 1 55  ? -19.02986 3.57168  1.37131   1.000 40.45617 ? 56  ALA A O   1 
ATOM   409  C CB  . ALA A 1 55  ? -19.32195 5.75233  3.89521   1.000 45.78274 ? 56  ALA A CB  1 
ATOM   410  N N   . LEU A 1 56  ? -19.46369 5.71025  0.80159   1.000 39.65806 ? 57  LEU A N   1 
ATOM   411  C CA  . LEU A 1 56  ? -20.17928 5.30516  -0.39989  1.000 38.12248 ? 57  LEU A CA  1 
ATOM   412  C C   . LEU A 1 56  ? -19.27836 4.50004  -1.32424  1.000 34.12967 ? 57  LEU A C   1 
ATOM   413  O O   . LEU A 1 56  ? -19.73598 3.56024  -1.98114  1.000 34.23975 ? 57  LEU A O   1 
ATOM   414  C CB  . LEU A 1 56  ? -20.73721 6.53441  -1.11875  1.000 37.04499 ? 57  LEU A CB  1 
ATOM   415  C CG  . LEU A 1 56  ? -21.83511 7.29581  -0.37370  1.000 38.61094 ? 57  LEU A CG  1 
ATOM   416  C CD1 . LEU A 1 56  ? -21.96855 8.71066  -0.91259  1.000 41.80082 ? 57  LEU A CD1 1 
ATOM   417  C CD2 . LEU A 1 56  ? -23.15740 6.56089  -0.44879  1.000 37.80609 ? 57  LEU A CD2 1 
ATOM   418  N N   . LEU A 1 57  ? -17.98811 4.83980  -1.37025  1.000 36.68996 ? 58  LEU A N   1 
ATOM   419  C CA  . LEU A 1 57  ? -17.07648 4.11037  -2.24340  1.000 38.64690 ? 58  LEU A CA  1 
ATOM   420  C C   . LEU A 1 57  ? -16.94709 2.65721  -1.80358  1.000 37.55403 ? 58  LEU A C   1 
ATOM   421  O O   . LEU A 1 57  ? -16.98615 1.74637  -2.63733  1.000 34.53192 ? 58  LEU A O   1 
ATOM   422  C CB  . LEU A 1 57  ? -15.71029 4.79240  -2.28116  1.000 33.93970 ? 58  LEU A CB  1 
ATOM   423  C CG  . LEU A 1 57  ? -14.78350 4.19514  -3.34429  1.000 35.47865 ? 58  LEU A CG  1 
ATOM   424  C CD1 . LEU A 1 57  ? -15.39472 4.36021  -4.72080  1.000 37.67150 ? 58  LEU A CD1 1 
ATOM   425  C CD2 . LEU A 1 57  ? -13.39805 4.82314  -3.29257  1.000 36.45899 ? 58  LEU A CD2 1 
ATOM   426  N N   . ILE A 1 58  ? -16.82808 2.42500  -0.49178  1.000 41.90799 ? 59  ILE A N   1 
ATOM   427  C CA  . ILE A 1 58  ? -16.77327 1.06136  0.03890   1.000 38.44204 ? 59  ILE A CA  1 
ATOM   428  C C   . ILE A 1 58  ? -18.01450 0.27609  -0.36645  1.000 39.20714 ? 59  ILE A C   1 
ATOM   429  O O   . ILE A 1 58  ? -17.92121 -0.86284 -0.83577  1.000 42.94341 ? 59  ILE A O   1 
ATOM   430  C CB  . ILE A 1 58  ? -16.61298 1.08658  1.56956   1.000 41.43843 ? 59  ILE A CB  1 
ATOM   431  C CG1 . ILE A 1 58  ? -15.48863 2.03368  1.98863   1.000 44.19080 ? 59  ILE A CG1 1 
ATOM   432  C CG2 . ILE A 1 58  ? -16.37635 -0.31551 2.10369   1.000 42.61475 ? 59  ILE A CG2 1 
ATOM   433  C CD1 . ILE A 1 58  ? -14.10509 1.51208  1.70878   1.000 42.88424 ? 59  ILE A CD1 1 
ATOM   434  N N   . SER A 1 59  ? -19.19894 0.87312  -0.18525  1.000 39.79630 ? 60  SER A N   1 
ATOM   435  C CA  . SER A 1 59  ? -20.45287 0.17757  -0.46939  1.000 39.43543 ? 60  SER A CA  1 
ATOM   436  C C   . SER A 1 59  ? -20.62946 -0.14704 -1.94716  1.000 39.51130 ? 60  SER A C   1 
ATOM   437  O O   . SER A 1 59  ? -21.50197 -0.95067 -2.29345  1.000 39.15726 ? 60  SER A O   1 
ATOM   438  C CB  . SER A 1 59  ? -21.64504 1.01356  0.01361   1.000 43.89794 ? 60  SER A CB  1 
ATOM   439  O OG  . SER A 1 59  ? -21.69883 2.26999  -0.65561  1.000 45.35787 ? 60  SER A OG  1 
ATOM   440  N N   . MET A 1 60  ? -19.83872 0.45564  -2.82678  1.000 38.04263 ? 61  MET A N   1 
ATOM   441  C CA  . MET A 1 60  ? -19.95908 0.18614  -4.24791  1.000 38.05320 ? 61  MET A CA  1 
ATOM   442  C C   . MET A 1 60  ? -19.12922 -1.03202 -4.63095  1.000 37.93716 ? 61  MET A C   1 
ATOM   443  O O   . MET A 1 60  ? -18.11160 -1.34093 -4.00549  1.000 41.15121 ? 61  MET A O   1 
ATOM   444  C CB  . MET A 1 60  ? -19.50776 1.39750  -5.08109  1.000 37.38638 ? 61  MET A CB  1 
ATOM   445  C CG  . MET A 1 60  ? -20.29896 2.67951  -4.84261  1.000 36.27310 ? 61  MET A CG  1 
ATOM   446  S SD  . MET A 1 60  ? -22.04754 2.48319  -5.19414  1.000 49.75518 ? 61  MET A SD  1 
ATOM   447  C CE  . MET A 1 60  ? -22.72213 3.99309  -4.52021  1.000 35.52360 ? 61  MET A CE  1 
ATOM   448  N N   . THR A 1 61  ? -19.59057 -1.73108 -5.66088  1.000 34.96296 ? 62  THR A N   1 
ATOM   449  C CA  . THR A 1 61  ? -18.79549 -2.70276 -6.38915  1.000 35.24423 ? 62  THR A CA  1 
ATOM   450  C C   . THR A 1 61  ? -18.76964 -2.28868 -7.85480  1.000 36.39380 ? 62  THR A C   1 
ATOM   451  O O   . THR A 1 61  ? -19.45782 -1.34935 -8.26714  1.000 32.24824 ? 62  THR A O   1 
ATOM   452  C CB  . THR A 1 61  ? -19.35187 -4.12352 -6.24306  1.000 36.99283 ? 62  THR A CB  1 
ATOM   453  O OG1 . THR A 1 61  ? -20.44836 -4.31037 -7.14698  1.000 37.51426 ? 62  THR A OG1 1 
ATOM   454  C CG2 . THR A 1 61  ? -19.82178 -4.37487 -4.80554  1.000 37.21149 ? 62  THR A CG2 1 
ATOM   455  N N   . ASN A 1 62  ? -17.96312 -3.00382 -8.64497  1.000 32.12219 ? 63  ASN A N   1 
ATOM   456  C CA  . ASN A 1 62  ? -17.93731 -2.76263 -10.08369 1.000 33.58995 ? 63  ASN A CA  1 
ATOM   457  C C   . ASN A 1 62  ? -19.33255 -2.80890 -10.69203 1.000 37.25649 ? 63  ASN A C   1 
ATOM   458  O O   . ASN A 1 62  ? -19.61382 -2.08167 -11.65274 1.000 30.29621 ? 63  ASN A O   1 
ATOM   459  C CB  . ASN A 1 62  ? -17.02937 -3.78071 -10.77458 1.000 31.71961 ? 63  ASN A CB  1 
ATOM   460  C CG  . ASN A 1 62  ? -15.56391 -3.56232 -10.45220 1.000 33.29028 ? 63  ASN A CG  1 
ATOM   461  O OD1 . ASN A 1 62  ? -15.15264 -2.45100 -10.11439 1.000 34.67863 ? 63  ASN A OD1 1 
ATOM   462  N ND2 . ASN A 1 62  ? -14.76775 -4.62475 -10.54649 1.000 33.26328 ? 63  ASN A ND2 1 
ATOM   463  N N   . HIS A 1 63  ? -20.22746 -3.63521 -10.13749 1.000 36.37817 ? 64  HIS A N   1 
ATOM   464  C CA  . HIS A 1 63  ? -21.57587 -3.77850 -10.68183 1.000 34.63880 ? 64  HIS A CA  1 
ATOM   465  C C   . HIS A 1 63  ? -22.50764 -2.62409 -10.32575 1.000 31.83178 ? 64  HIS A C   1 
ATOM   466  O O   . HIS A 1 63  ? -23.63594 -2.58211 -10.82875 1.000 35.93408 ? 64  HIS A O   1 
ATOM   467  C CB  . HIS A 1 63  ? -22.18384 -5.09906 -10.20313 1.000 38.99867 ? 64  HIS A CB  1 
ATOM   468  C CG  . HIS A 1 63  ? -21.46306 -6.29944 -10.72285 1.000 40.47461 ? 64  HIS A CG  1 
ATOM   469  N ND1 . HIS A 1 63  ? -21.51741 -6.68049 -12.04796 1.000 46.57159 ? 64  HIS A ND1 1 
ATOM   470  C CD2 . HIS A 1 63  ? -20.63011 -7.17397 -10.11064 1.000 41.35613 ? 64  HIS A CD2 1 
ATOM   471  C CE1 . HIS A 1 63  ? -20.75969 -7.74758 -12.22607 1.000 46.00456 ? 64  HIS A CE1 1 
ATOM   472  N NE2 . HIS A 1 63  ? -20.21332 -8.06870 -11.06553 1.000 43.49555 ? 64  HIS A NE2 1 
ATOM   473  N N   . SER A 1 64  ? -22.07963 -1.68717 -9.48818  1.000 34.07871 ? 65  SER A N   1 
ATOM   474  C CA  . SER A 1 64  ? -22.92670 -0.54688 -9.16553  1.000 32.31180 ? 65  SER A CA  1 
ATOM   475  C C   . SER A 1 64  ? -22.96248 0.51669  -10.25487 1.000 32.49220 ? 65  SER A C   1 
ATOM   476  O O   . SER A 1 64  ? -23.78356 1.43190  -10.15596 1.000 32.36082 ? 65  SER A O   1 
ATOM   477  C CB  . SER A 1 64  ? -22.46879 0.11141  -7.86622  1.000 32.47529 ? 65  SER A CB  1 
ATOM   478  O OG  . SER A 1 64  ? -21.99834 -0.85255 -6.96155  1.000 36.29646 ? 65  SER A OG  1 
ATOM   479  N N   . PHE A 1 65  ? -22.10575 0.43546  -11.27556 1.000 30.86841 ? 66  PHE A N   1 
ATOM   480  C CA  . PHE A 1 65  ? -22.00669 1.46947  -12.30232 1.000 30.57621 ? 66  PHE A CA  1 
ATOM   481  C C   . PHE A 1 65  ? -22.33024 0.88061  -13.66699 1.000 32.73748 ? 66  PHE A C   1 
ATOM   482  O O   . PHE A 1 65  ? -21.75273 -0.14014 -14.05932 1.000 33.59454 ? 66  PHE A O   1 
ATOM   483  C CB  . PHE A 1 65  ? -20.60329 2.08908  -12.34498 1.000 26.07086 ? 66  PHE A CB  1 
ATOM   484  C CG  . PHE A 1 65  ? -20.07593 2.50298  -11.00735 1.000 27.66010 ? 66  PHE A CG  1 
ATOM   485  C CD1 . PHE A 1 65  ? -20.34765 3.76521  -10.49734 1.000 28.18565 ? 66  PHE A CD1 1 
ATOM   486  C CD2 . PHE A 1 65  ? -19.28764 1.63941  -10.26033 1.000 28.69946 ? 66  PHE A CD2 1 
ATOM   487  C CE1 . PHE A 1 65  ? -19.84987 4.15168  -9.27080  1.000 26.09553 ? 66  PHE A CE1 1 
ATOM   488  C CE2 . PHE A 1 65  ? -18.77544 2.02686  -9.03609  1.000 27.68280 ? 66  PHE A CE2 1 
ATOM   489  C CZ  . PHE A 1 65  ? -19.06359 3.28245  -8.53809  1.000 30.56486 ? 66  PHE A CZ  1 
ATOM   490  N N   . SER A 1 66  ? -23.24073 1.52351  -14.38971 1.000 29.43765 ? 67  SER A N   1 
ATOM   491  C CA  . SER A 1 66  ? -23.52434 1.18673  -15.78006 1.000 28.11108 ? 67  SER A CA  1 
ATOM   492  C C   . SER A 1 66  ? -22.95485 2.28231  -16.67027 1.000 30.32284 ? 67  SER A C   1 
ATOM   493  O O   . SER A 1 66  ? -23.22111 3.46645  -16.44118 1.000 26.47417 ? 67  SER A O   1 
ATOM   494  C CB  . SER A 1 66  ? -25.03283 1.06254  -16.03063 1.000 32.50372 ? 67  SER A CB  1 
ATOM   495  O OG  . SER A 1 66  ? -25.61480 0.02149  -15.26241 1.000 45.72772 ? 67  SER A OG  1 
ATOM   496  N N   . VAL A 1 67  ? -22.20076 1.89821  -17.69411 1.000 27.47271 ? 68  VAL A N   1 
ATOM   497  C CA  . VAL A 1 67  ? -21.62425 2.86200  -18.62120 1.000 23.93613 ? 68  VAL A CA  1 
ATOM   498  C C   . VAL A 1 67  ? -22.09214 2.53055  -20.03280 1.000 28.80680 ? 68  VAL A C   1 
ATOM   499  O O   . VAL A 1 67  ? -21.92917 1.39496  -20.49745 1.000 26.45948 ? 68  VAL A O   1 
ATOM   500  C CB  . VAL A 1 67  ? -20.08836 2.88169  -18.52876 1.000 27.48568 ? 68  VAL A CB  1 
ATOM   501  C CG1 . VAL A 1 67  ? -19.50902 3.93582  -19.46577 1.000 23.66664 ? 68  VAL A CG1 1 
ATOM   502  C CG2 . VAL A 1 67  ? -19.64347 3.13822  -17.08962 1.000 23.17266 ? 68  VAL A CG2 1 
ATOM   503  N N   . GLN A 1 68  ? -22.63553 3.53766  -20.72402 1.000 24.79470 ? 69  GLN A N   1 
ATOM   504  C CA  . GLN A 1 68  ? -23.13779 3.41324  -22.08578 1.000 27.75187 ? 69  GLN A CA  1 
ATOM   505  C C   . GLN A 1 68  ? -22.53771 4.49270  -22.97917 1.000 31.10930 ? 69  GLN A C   1 
ATOM   506  O O   . GLN A 1 68  ? -22.48554 5.66205  -22.59178 1.000 24.61657 ? 69  GLN A O   1 
ATOM   507  C CB  . GLN A 1 68  ? -24.67401 3.53670  -22.11337 1.000 31.43087 ? 69  GLN A CB  1 
ATOM   508  C CG  . GLN A 1 68  ? -25.42107 2.21856  -21.99591 1.000 39.30601 ? 69  GLN A CG  1 
ATOM   509  C CD  . GLN A 1 68  ? -26.78421 2.28661  -22.66833 1.000 34.88060 ? 69  GLN A CD  1 
ATOM   510  O OE1 . GLN A 1 68  ? -27.66878 2.99237  -22.20530 1.000 33.94357 ? 69  GLN A OE1 1 
ATOM   511  N NE2 . GLN A 1 68  ? -26.94361 1.57269  -23.77853 1.000 36.36905 ? 69  GLN A NE2 1 
ATOM   512  N N   . LYS A 1 69  ? -22.10322 4.10786  -24.17967 1.000 30.62827 ? 70  LYS A N   1 
ATOM   513  C CA  . LYS A 1 69  ? -21.74247 5.06270  -25.22599 1.000 35.03534 ? 70  LYS A CA  1 
ATOM   514  C C   . LYS A 1 69  ? -22.84796 5.06908  -26.27885 1.000 41.68051 ? 70  LYS A C   1 
ATOM   515  O O   . LYS A 1 69  ? -23.13993 4.02747  -26.88135 1.000 38.68064 ? 70  LYS A O   1 
ATOM   516  C CB  . LYS A 1 69  ? -20.39478 4.71775  -25.86404 1.000 37.54200 ? 70  LYS A CB  1 
ATOM   517  C CG  . LYS A 1 69  ? -19.84843 5.83480  -26.76204 1.000 40.37097 ? 70  LYS A CG  1 
ATOM   518  C CD  . LYS A 1 69  ? -18.63317 5.36907  -27.54703 1.000 41.24256 ? 70  LYS A CD  1 
ATOM   519  C CE  . LYS A 1 69  ? -18.66210 5.87577  -28.98083 1.000 43.19714 ? 70  LYS A CE  1 
ATOM   520  N NZ  . LYS A 1 69  ? -18.18681 7.24942  -29.13155 1.000 41.21643 ? 70  LYS A NZ  1 
ATOM   521  N N   . HIS A 1 70  ? -23.45971 6.23965  -26.49607 1.000 38.90108 ? 71  HIS A N   1 
ATOM   522  C CA  . HIS A 1 70  ? -24.56766 6.39238  -27.43415 1.000 38.91133 ? 71  HIS A CA  1 
ATOM   523  C C   . HIS A 1 70  ? -24.13133 6.92291  -28.79084 1.000 40.44894 ? 71  HIS A C   1 
ATOM   524  O O   . HIS A 1 70  ? -24.58147 6.42859  -29.82962 1.000 42.01253 ? 71  HIS A O   1 
ATOM   525  C CB  . HIS A 1 70  ? -25.61938 7.34440  -26.85868 1.000 38.39573 ? 71  HIS A CB  1 
ATOM   526  C CG  . HIS A 1 70  ? -26.15492 6.93102  -25.52330 1.000 36.93501 ? 71  HIS A CG  1 
ATOM   527  N ND1 . HIS A 1 70  ? -26.89115 5.78029  -25.33873 1.000 38.17414 ? 71  HIS A ND1 1 
ATOM   528  C CD2 . HIS A 1 70  ? -26.09151 7.53492  -24.31062 1.000 34.58714 ? 71  HIS A CD2 1 
ATOM   529  C CE1 . HIS A 1 70  ? -27.24019 5.67900  -24.06624 1.000 36.59179 ? 71  HIS A CE1 1 
ATOM   530  N NE2 . HIS A 1 70  ? -26.77135 6.73402  -23.42124 1.000 34.72734 ? 71  HIS A NE2 1 
ATOM   531  N N   . ILE A 1 71  ? -23.27419 7.94049  -28.77811 1.000 40.34226 ? 72  ILE A N   1 
ATOM   532  C CA  . ILE A 1 71  ? -22.79182 8.57568  -29.99180 1.000 47.17289 ? 72  ILE A CA  1 
ATOM   533  C C   . ILE A 1 71  ? -21.96927 7.59091  -30.80965 1.000 46.74160 ? 72  ILE A C   1 
ATOM   534  O O   . ILE A 1 71  ? -21.40578 6.62743  -30.27722 1.000 49.06033 ? 72  ILE A O   1 
ATOM   535  C CB  . ILE A 1 71  ? -21.96065 9.80358  -29.57693 1.000 48.14001 ? 72  ILE A CB  1 
ATOM   536  C CG1 . ILE A 1 71  ? -22.79651 10.68749 -28.65417 1.000 43.59518 ? 72  ILE A CG1 1 
ATOM   537  C CG2 . ILE A 1 71  ? -21.41932 10.58756 -30.77390 1.000 49.28898 ? 72  ILE A CG2 1 
ATOM   538  C CD1 . ILE A 1 71  ? -24.20064 10.96235 -29.15217 1.000 40.59271 ? 72  ILE A CD1 1 
ATOM   539  N N   . GLY A 1 72  ? -21.91366 7.82710  -32.11827 1.000 45.44342 ? 73  GLY A N   1 
ATOM   540  C CA  . GLY A 1 72  ? -20.93772 7.15105  -32.96166 1.000 49.47918 ? 73  GLY A CA  1 
ATOM   541  C C   . GLY A 1 72  ? -21.04961 5.64251  -32.88987 1.000 50.66286 ? 73  GLY A C   1 
ATOM   542  O O   . GLY A 1 72  ? -22.13393 5.06920  -33.04193 1.000 51.48006 ? 73  GLY A O   1 
ATOM   543  N N   . ALA A 1 73  ? -19.90207 4.98827  -32.65266 1.000 52.46215 ? 74  ALA A N   1 
ATOM   544  C CA  . ALA A 1 73  ? -19.78771 3.54223  -32.49720 1.000 53.66496 ? 74  ALA A CA  1 
ATOM   545  C C   . ALA A 1 73  ? -20.19816 3.12617  -31.08811 1.000 52.56926 ? 74  ALA A C   1 
ATOM   546  O O   . ALA A 1 73  ? -19.43256 3.33165  -30.14078 1.000 56.95055 ? 74  ALA A O   1 
ATOM   547  C CB  . ALA A 1 73  ? -18.35382 3.09458  -32.78856 1.000 56.67548 ? 74  ALA A CB  1 
ATOM   548  N N   . PRO A 1 74  ? -21.36325 2.51417  -30.90914 1.000 51.21109 ? 75  PRO A N   1 
ATOM   549  C CA  . PRO A 1 74  ? -21.94759 2.35487  -29.56542 1.000 52.92828 ? 75  PRO A CA  1 
ATOM   550  C C   . PRO A 1 74  ? -21.35532 1.19415  -28.75517 1.000 56.37042 ? 75  PRO A C   1 
ATOM   551  O O   . PRO A 1 74  ? -20.46638 0.47194  -29.20923 1.000 58.27579 ? 75  PRO A O   1 
ATOM   552  C CB  . PRO A 1 74  ? -23.43605 2.12379  -29.86474 1.000 46.25452 ? 75  PRO A CB  1 
ATOM   553  C CG  . PRO A 1 74  ? -23.62109 2.55716  -31.31222 1.000 48.39222 ? 75  PRO A CG  1 
ATOM   554  C CD  . PRO A 1 74  ? -22.33196 2.19793  -31.96617 1.000 50.07716 ? 75  PRO A CD  1 
ATOM   555  N N   . ALA A 1 75  ? -21.89468 1.04785  -27.52486 1.000 51.69877 ? 76  ALA A N   1 
ATOM   556  C CA  . ALA A 1 75  ? -21.56110 0.13206  -26.41704 1.000 48.60096 ? 76  ALA A CA  1 
ATOM   557  C C   . ALA A 1 75  ? -22.03100 0.85538  -25.14714 1.000 43.80401 ? 76  ALA A C   1 
ATOM   558  O O   . ALA A 1 75  ? -22.20706 2.06828  -25.23484 1.000 48.57337 ? 76  ALA A O   1 
ATOM   559  C CB  . ALA A 1 75  ? -20.07102 -0.21075 -26.36753 1.000 45.22957 ? 76  ALA A CB  1 
ATOM   560  N N   . ASN A 1 76  ? -22.28500 0.24688  -23.97048 1.000 47.50508 ? 77  ASN A N   1 
ATOM   561  C CA  . ASN A 1 76  ? -22.19635 -1.14313 -23.46791 1.000 45.80503 ? 77  ASN A CA  1 
ATOM   562  C C   . ASN A 1 76  ? -20.75049 -1.54453 -23.09263 1.000 43.06874 ? 77  ASN A C   1 
ATOM   563  O O   . ASN A 1 76  ? -20.14449 -2.45832 -23.65275 1.000 39.67035 ? 77  ASN A O   1 
ATOM   564  C CB  . ASN A 1 76  ? -22.85936 -2.13511 -24.42928 1.000 51.23109 ? 77  ASN A CB  1 
ATOM   565  C CG  . ASN A 1 76  ? -24.37931 -1.95792 -24.47250 1.000 48.94770 ? 77  ASN A CG  1 
ATOM   566  O OD1 . ASN A 1 76  ? -24.89045 -0.84612 -24.27698 1.000 47.02612 ? 77  ASN A OD1 1 
ATOM   567  N ND2 . ASN A 1 76  ? -25.10418 -3.04590 -24.72539 1.000 45.94467 ? 77  ASN A ND2 1 
ATOM   568  N N   . LEU A 1 77  ? -20.23987 -0.83666 -22.08916 1.000 39.93263 ? 78  LEU A N   1 
ATOM   569  C CA  . LEU A 1 77  ? -18.92853 -1.06516 -21.49736 1.000 36.58160 ? 78  LEU A CA  1 
ATOM   570  C C   . LEU A 1 77  ? -19.10571 -1.82722 -20.19391 1.000 33.22560 ? 78  LEU A C   1 
ATOM   571  O O   . LEU A 1 77  ? -20.12809 -1.68977 -19.52284 1.000 37.33001 ? 78  LEU A O   1 
ATOM   572  C CB  . LEU A 1 77  ? -18.21356 0.26529  -21.21110 1.000 30.84916 ? 78  LEU A CB  1 
ATOM   573  C CG  . LEU A 1 77  ? -17.49379 1.00731  -22.34132 1.000 34.22482 ? 78  LEU A CG  1 
ATOM   574  C CD1 . LEU A 1 77  ? -18.25220 0.96917  -23.64178 1.000 39.00367 ? 78  LEU A CD1 1 
ATOM   575  C CD2 . LEU A 1 77  ? -17.17028 2.45799  -21.93873 1.000 26.93396 ? 78  LEU A CD2 1 
ATOM   576  N N   . ARG A 1 78  ? -18.10241 -2.61348 -19.82350 1.000 30.80010 ? 79  ARG A N   1 
ATOM   577  C CA  . ARG A 1 78  ? -18.12625 -3.35412 -18.56755 1.000 31.36011 ? 79  ARG A CA  1 
ATOM   578  C C   . ARG A 1 78  ? -17.11848 -2.73573 -17.60549 1.000 29.24752 ? 79  ARG A C   1 
ATOM   579  O O   . ARG A 1 78  ? -15.93623 -2.61510 -17.93557 1.000 30.73018 ? 79  ARG A O   1 
ATOM   580  C CB  . ARG A 1 78  ? -17.82680 -4.83709 -18.79720 1.000 37.10559 ? 79  ARG A CB  1 
ATOM   581  C CG  . ARG A 1 78  ? -18.40293 -5.74012 -17.71022 1.000 39.78440 ? 79  ARG A CG  1 
ATOM   582  C CD  . ARG A 1 78  ? -18.14670 -7.21036 -17.98409 1.000 49.08702 ? 79  ARG A CD  1 
ATOM   583  N NE  . ARG A 1 78  ? -16.78644 -7.44904 -18.46035 1.000 56.09105 ? 79  ARG A NE  1 
ATOM   584  C CZ  . ARG A 1 78  ? -15.83270 -8.04683 -17.74702 1.000 58.37235 ? 79  ARG A CZ  1 
ATOM   585  N NH1 . ARG A 1 78  ? -16.08840 -8.46373 -16.51244 1.000 57.52533 ? 79  ARG A NH1 1 
ATOM   586  N NH2 . ARG A 1 78  ? -14.62073 -8.22741 -18.26892 1.000 58.30776 ? 79  ARG A NH2 1 
ATOM   587  N N   . VAL A 1 79  ? -17.58459 -2.32571 -16.43451 1.000 26.09309 ? 80  VAL A N   1 
ATOM   588  C CA  . VAL A 1 79  ? -16.69941 -1.75145 -15.42411 1.000 24.56226 ? 80  VAL A CA  1 
ATOM   589  C C   . VAL A 1 79  ? -15.99224 -2.89213 -14.70895 1.000 31.43777 ? 80  VAL A C   1 
ATOM   590  O O   . VAL A 1 79  ? -16.63778 -3.82827 -14.22822 1.000 28.57915 ? 80  VAL A O   1 
ATOM   591  C CB  . VAL A 1 79  ? -17.48559 -0.87659 -14.43279 1.000 25.91921 ? 80  VAL A CB  1 
ATOM   592  C CG1 . VAL A 1 79  ? -16.58761 -0.42939 -13.28108 1.000 23.10042 ? 80  VAL A CG1 1 
ATOM   593  C CG2 . VAL A 1 79  ? -18.09982 0.34334  -15.14549 1.000 29.49198 ? 80  VAL A CG2 1 
ATOM   594  N N   . VAL A 1 80  ? -14.66303 -2.82830 -14.64497 1.000 29.71514 ? 81  VAL A N   1 
ATOM   595  C CA  . VAL A 1 80  ? -13.86835 -3.87233 -14.01345 1.000 27.72668 ? 81  VAL A CA  1 
ATOM   596  C C   . VAL A 1 80  ? -13.01693 -3.32920 -12.87856 1.000 31.28850 ? 81  VAL A C   1 
ATOM   597  O O   . VAL A 1 80  ? -12.19815 -4.05961 -12.31113 1.000 29.78730 ? 81  VAL A O   1 
ATOM   598  C CB  . VAL A 1 80  ? -12.99540 -4.61863 -15.04173 1.000 30.13026 ? 81  VAL A CB  1 
ATOM   599  C CG1 . VAL A 1 80  ? -13.87040 -5.36468 -16.03740 1.000 31.06783 ? 81  VAL A CG1 1 
ATOM   600  C CG2 . VAL A 1 80  ? -12.02539 -3.63639 -15.74451 1.000 27.54798 ? 81  VAL A CG2 1 
ATOM   601  N N   . GLY A 1 81  ? -13.19297 -2.05735 -12.53623 1.000 26.94371 ? 82  GLY A N   1 
ATOM   602  C CA  . GLY A 1 81  ? -12.51126 -1.45745 -11.40899 1.000 28.61991 ? 82  GLY A CA  1 
ATOM   603  C C   . GLY A 1 81  ? -13.05258 -0.07687 -11.09550 1.000 30.99022 ? 82  GLY A C   1 
ATOM   604  O O   . GLY A 1 81  ? -13.58612 0.61258  -11.97706 1.000 27.77701 ? 82  GLY A O   1 
ATOM   605  N N   . HIS A 1 82  ? -12.91200 0.35301  -9.84547  1.000 28.61466 ? 83  HIS A N   1 
ATOM   606  C CA  . HIS A 1 82  ? -13.37825 1.68040  -9.48145  1.000 27.66854 ? 83  HIS A CA  1 
ATOM   607  C C   . HIS A 1 82  ? -12.48299 2.23776  -8.39380  1.000 31.12213 ? 83  HIS A C   1 
ATOM   608  O O   . HIS A 1 82  ? -12.03597 1.51083  -7.49693  1.000 27.53754 ? 83  HIS A O   1 
ATOM   609  C CB  . HIS A 1 82  ? -14.84222 1.66670  -9.02583  1.000 30.83081 ? 83  HIS A CB  1 
ATOM   610  C CG  . HIS A 1 82  ? -15.08593 0.84634  -7.79853  1.000 34.37284 ? 83  HIS A CG  1 
ATOM   611  N ND1 . HIS A 1 82  ? -15.16891 -0.52977 -7.82993  1.000 33.99101 ? 83  HIS A ND1 1 
ATOM   612  C CD2 . HIS A 1 82  ? -15.28055 1.20764  -6.50741  1.000 36.69660 ? 83  HIS A CD2 1 
ATOM   613  C CE1 . HIS A 1 82  ? -15.38973 -0.98321 -6.60771  1.000 36.06951 ? 83  HIS A CE1 1 
ATOM   614  N NE2 . HIS A 1 82  ? -15.46620 0.05029  -5.78731  1.000 37.86020 ? 83  HIS A NE2 1 
ATOM   615  N N   . ALA A 1 83  ? -12.21523 3.53454  -8.49863  1.000 26.62876 ? 84  ALA A N   1 
ATOM   616  C CA  . ALA A 1 83  ? -11.40757 4.24462  -7.53030  1.000 25.78032 ? 84  ALA A CA  1 
ATOM   617  C C   . ALA A 1 83  ? -11.90272 5.67677  -7.49234  1.000 29.47425 ? 84  ALA A C   1 
ATOM   618  O O   . ALA A 1 83  ? -12.64716 6.12152  -8.37148  1.000 28.20718 ? 84  ALA A O   1 
ATOM   619  C CB  . ALA A 1 83  ? -9.91349  4.18947  -7.87420  1.000 26.02653 ? 84  ALA A CB  1 
ATOM   620  N N   . MET A 1 84  ? -11.49219 6.39616  -6.46493  1.000 28.01340 ? 85  MET A N   1 
ATOM   621  C CA  . MET A 1 84  ? -11.91799 7.77301  -6.28685  1.000 28.53547 ? 85  MET A CA  1 
ATOM   622  C C   . MET A 1 84  ? -10.68929 8.65908  -6.16750  1.000 31.06947 ? 85  MET A C   1 
ATOM   623  O O   . MET A 1 84  ? -9.70341  8.28788  -5.52565  1.000 29.72229 ? 85  MET A O   1 
ATOM   624  C CB  . MET A 1 84  ? -12.81932 7.91550  -5.06610  1.000 31.49928 ? 85  MET A CB  1 
ATOM   625  C CG  . MET A 1 84  ? -13.26423 9.33814  -4.79591  1.000 27.85520 ? 85  MET A CG  1 
ATOM   626  S SD  . MET A 1 84  ? -14.48683 9.48261  -3.46638  1.000 35.65870 ? 85  MET A SD  1 
ATOM   627  C CE  . MET A 1 84  ? -13.60564 8.72356  -2.08121  1.000 32.40583 ? 85  MET A CE  1 
ATOM   628  N N   . GLN A 1 85  ? -10.74128 9.82415  -6.80741  1.000 27.93520 ? 86  GLN A N   1 
ATOM   629  C CA  . GLN A 1 85  ? -9.57957  10.70797 -6.87262  1.000 30.06418 ? 86  GLN A CA  1 
ATOM   630  C C   . GLN A 1 85  ? -10.08147 12.12460 -6.62859  1.000 27.91610 ? 86  GLN A C   1 
ATOM   631  O O   . GLN A 1 85  ? -10.57271 12.77268 -7.55436  1.000 27.85294 ? 86  GLN A O   1 
ATOM   632  C CB  . GLN A 1 85  ? -8.87681  10.57725 -8.21720  1.000 29.21861 ? 86  GLN A CB  1 
ATOM   633  C CG  . GLN A 1 85  ? -7.51750  11.23471 -8.29182  1.000 32.24585 ? 86  GLN A CG  1 
ATOM   634  C CD  . GLN A 1 85  ? -6.81192  10.91132 -9.59028  1.000 38.15633 ? 86  GLN A CD  1 
ATOM   635  O OE1 . GLN A 1 85  ? -6.45320  9.76262  -9.84674  1.000 37.79346 ? 86  GLN A OE1 1 
ATOM   636  N NE2 . GLN A 1 85  ? -6.63484  11.92563 -10.43668 1.000 39.90462 ? 86  GLN A NE2 1 
ATOM   637  N N   . GLY A 1 86  ? -9.95560  12.59630 -5.38936  1.000 24.87174 ? 87  GLY A N   1 
ATOM   638  C CA  . GLY A 1 86  ? -10.52929 13.88286 -5.03226  1.000 26.45778 ? 87  GLY A CA  1 
ATOM   639  C C   . GLY A 1 86  ? -12.02889 13.83337 -5.25133  1.000 29.86230 ? 87  GLY A C   1 
ATOM   640  O O   . GLY A 1 86  ? -12.72325 12.97236 -4.70264  1.000 28.50272 ? 87  GLY A O   1 
ATOM   641  N N   . THR A 1 87  ? -12.54479 14.72919 -6.09717  1.000 26.92459 ? 88  THR A N   1 
ATOM   642  C CA  . THR A 1 87  ? -13.97077 14.79657 -6.38826  1.000 24.83991 ? 88  THR A CA  1 
ATOM   643  C C   . THR A 1 87  ? -14.37906 14.00783 -7.63384  1.000 25.39532 ? 88  THR A C   1 
ATOM   644  O O   . THR A 1 87  ? -15.50133 14.18723 -8.12587  1.000 24.16660 ? 88  THR A O   1 
ATOM   645  C CB  . THR A 1 87  ? -14.39800 16.25724 -6.55712  1.000 26.70993 ? 88  THR A CB  1 
ATOM   646  O OG1 . THR A 1 87  ? -13.64628 16.85050 -7.62859  1.000 26.86057 ? 88  THR A OG1 1 
ATOM   647  C CG2 . THR A 1 87  ? -14.16871 17.03604 -5.26369  1.000 28.26228 ? 88  THR A CG2 1 
ATOM   648  N N   . LEU A 1 88  ? -13.51532 13.14794 -8.15455  1.000 22.73493 ? 89  LEU A N   1 
ATOM   649  C CA  . LEU A 1 88  ? -13.81880 12.40008 -9.35777  1.000 25.41855 ? 89  LEU A CA  1 
ATOM   650  C C   . LEU A 1 88  ? -13.82730 10.90092 -9.08708  1.000 25.44225 ? 89  LEU A C   1 
ATOM   651  O O   . LEU A 1 88  ? -13.08548 10.39353 -8.23881  1.000 25.49502 ? 89  LEU A O   1 
ATOM   652  C CB  . LEU A 1 88  ? -12.80219 12.72021 -10.47026 1.000 21.88237 ? 89  LEU A CB  1 
ATOM   653  C CG  . LEU A 1 88  ? -12.83976 14.13182 -11.03627 1.000 24.27825 ? 89  LEU A CG  1 
ATOM   654  C CD1 . LEU A 1 88  ? -11.83241 14.21207 -12.17827 1.000 26.34952 ? 89  LEU A CD1 1 
ATOM   655  C CD2 . LEU A 1 88  ? -14.23505 14.50770 -11.51510 1.000 22.07397 ? 89  LEU A CD2 1 
ATOM   656  N N   . LEU A 1 89  ? -14.67775 10.19258 -9.81844  1.000 25.05450 ? 90  LEU A N   1 
ATOM   657  C CA  . LEU A 1 89  ? -14.56413 8.74362  -9.92122  1.000 26.93621 ? 90  LEU A CA  1 
ATOM   658  C C   . LEU A 1 89  ? -13.67512 8.37893  -11.09924 1.000 29.42263 ? 90  LEU A C   1 
ATOM   659  O O   . LEU A 1 89  ? -13.76214 8.96891  -12.18593 1.000 22.94419 ? 90  LEU A O   1 
ATOM   660  C CB  . LEU A 1 89  ? -15.92583 8.06821  -10.10117 1.000 24.37113 ? 90  LEU A CB  1 
ATOM   661  C CG  . LEU A 1 89  ? -16.75051 7.78466  -8.85111  1.000 31.05391 ? 90  LEU A CG  1 
ATOM   662  C CD1 . LEU A 1 89  ? -17.97586 7.01276  -9.26221  1.000 33.06509 ? 90  LEU A CD1 1 
ATOM   663  C CD2 . LEU A 1 89  ? -15.94418 6.99177  -7.82339  1.000 36.89807 ? 90  LEU A CD2 1 
ATOM   664  N N   . LYS A 1 90  ? -12.84509 7.37781  -10.88196 1.000 25.51391 ? 91  LYS A N   1 
ATOM   665  C CA  . LYS A 1 90  ? -12.00378 6.79800  -11.91337 1.000 25.05140 ? 91  LYS A CA  1 
ATOM   666  C C   . LYS A 1 90  ? -12.44352 5.34469  -12.05849 1.000 26.25691 ? 91  LYS A C   1 
ATOM   667  O O   . LYS A 1 90  ? -12.07706 4.48972  -11.24564 1.000 26.51627 ? 91  LYS A O   1 
ATOM   668  C CB  . LYS A 1 90  ? -10.53672 6.94589  -11.52864 1.000 25.94405 ? 91  LYS A CB  1 
ATOM   669  C CG  . LYS A 1 90  ? -9.56705  6.55186  -12.58775 1.000 29.64733 ? 91  LYS A CG  1 
ATOM   670  C CD  . LYS A 1 90  ? -8.12789  6.90421  -12.22229 1.000 33.76800 ? 91  LYS A CD  1 
ATOM   671  C CE  . LYS A 1 90  ? -7.16459  6.12803  -13.11626 1.000 38.08663 ? 91  LYS A CE  1 
ATOM   672  N NZ  . LYS A 1 90  ? -5.75429  6.53450  -12.92047 1.000 37.47350 ? 91  LYS A NZ  1 
ATOM   673  N N   . LEU A 1 91  ? -13.26884 5.07317  -13.06176 1.000 23.99321 ? 92  LEU A N   1 
ATOM   674  C CA  . LEU A 1 91  ? -13.70596 3.71686  -13.35986 1.000 26.30319 ? 92  LEU A CA  1 
ATOM   675  C C   . LEU A 1 91  ? -12.79166 3.11878  -14.41307 1.000 28.55135 ? 92  LEU A C   1 
ATOM   676  O O   . LEU A 1 91  ? -12.38138 3.80458  -15.35175 1.000 27.50486 ? 92  LEU A O   1 
ATOM   677  C CB  . LEU A 1 91  ? -15.14666 3.69617  -13.86376 1.000 24.01235 ? 92  LEU A CB  1 
ATOM   678  C CG  . LEU A 1 91  ? -16.15926 4.44145  -12.99180 1.000 28.88765 ? 92  LEU A CG  1 
ATOM   679  C CD1 . LEU A 1 91  ? -17.50908 4.55609  -13.69503 1.000 25.82555 ? 92  LEU A CD1 1 
ATOM   680  C CD2 . LEU A 1 91  ? -16.30660 3.77492  -11.61901 1.000 27.62731 ? 92  LEU A CD2 1 
ATOM   681  N N   . THR A 1 92  ? -12.43695 1.85239  -14.22765 1.000 26.22721 ? 93  THR A N   1 
ATOM   682  C CA  . THR A 1 92  ? -11.71568 1.08953  -15.23356 1.000 23.21323 ? 93  THR A CA  1 
ATOM   683  C C   . THR A 1 92  ? -12.70718 0.21479  -15.98898 1.000 25.99032 ? 93  THR A C   1 
ATOM   684  O O   . THR A 1 92  ? -13.49886 -0.50875 -15.37642 1.000 27.83207 ? 93  THR A O   1 
ATOM   685  C CB  . THR A 1 92  ? -10.61789 0.23849  -14.58565 1.000 25.27969 ? 93  THR A CB  1 
ATOM   686  O OG1 . THR A 1 92  ? -9.80173  1.07645  -13.76316 1.000 25.72494 ? 93  THR A OG1 1 
ATOM   687  C CG2 . THR A 1 92  ? -9.74346  -0.41980 -15.63818 1.000 25.52008 ? 93  THR A CG2 1 
ATOM   688  N N   . VAL A 1 93  ? -12.67138 0.28860  -17.31312 1.000 21.80682 ? 94  VAL A N   1 
ATOM   689  C CA  . VAL A 1 93  ? -13.54332 -0.51151 -18.15831 1.000 24.61080 ? 94  VAL A CA  1 
ATOM   690  C C   . VAL A 1 93  ? -12.67711 -1.45662 -18.97496 1.000 27.77643 ? 94  VAL A C   1 
ATOM   691  O O   . VAL A 1 93  ? -11.46155 -1.27654 -19.09666 1.000 27.45242 ? 94  VAL A O   1 
ATOM   692  C CB  . VAL A 1 93  ? -14.42738 0.36953  -19.05699 1.000 26.98209 ? 94  VAL A CB  1 
ATOM   693  C CG1 . VAL A 1 93  ? -15.33560 1.22883  -18.16411 1.000 23.64620 ? 94  VAL A CG1 1 
ATOM   694  C CG2 . VAL A 1 93  ? -13.55372 1.26646  -19.92644 1.000 22.78610 ? 94  VAL A CG2 1 
ATOM   695  N N   . ASP A 1 94  ? -13.30705 -2.49048 -19.51913 1.000 26.60878 ? 95  ASP A N   1 
ATOM   696  C CA  . ASP A 1 94  ? -12.53529 -3.57207 -20.10736 1.000 27.17816 ? 95  ASP A CA  1 
ATOM   697  C C   . ASP A 1 94  ? -12.28672 -3.38930 -21.59523 1.000 28.07259 ? 95  ASP A C   1 
ATOM   698  O O   . ASP A 1 94  ? -11.69685 -4.28064 -22.20985 1.000 26.31489 ? 95  ASP A O   1 
ATOM   699  C CB  . ASP A 1 94  ? -13.21430 -4.92878 -19.84728 1.000 31.52448 ? 95  ASP A CB  1 
ATOM   700  C CG  . ASP A 1 94  ? -14.50428 -5.10869 -20.62580 1.000 36.93879 ? 95  ASP A CG  1 
ATOM   701  O OD1 . ASP A 1 94  ? -15.12866 -4.09964 -21.00601 1.000 36.51017 ? 95  ASP A OD1 1 
ATOM   702  O OD2 . ASP A 1 94  ? -14.91478 -6.27691 -20.83116 1.000 48.10423 ? 95  ASP A OD2 1 
ATOM   703  N N   . VAL A 1 95  ? -12.70574 -2.26389 -22.18067 1.000 24.07590 ? 96  VAL A N   1 
ATOM   704  C CA  . VAL A 1 95  ? -12.39496 -1.91628 -23.56819 1.000 25.71793 ? 96  VAL A CA  1 
ATOM   705  C C   . VAL A 1 95  ? -11.70617 -0.55676 -23.58699 1.000 24.99793 ? 96  VAL A C   1 
ATOM   706  O O   . VAL A 1 95  ? -12.18877 0.39520  -22.96196 1.000 24.29054 ? 96  VAL A O   1 
ATOM   707  C CB  . VAL A 1 95  ? -13.65726 -1.87959 -24.45054 1.000 26.90664 ? 96  VAL A CB  1 
ATOM   708  C CG1 . VAL A 1 95  ? -13.34686 -1.26361 -25.80711 1.000 26.38704 ? 96  VAL A CG1 1 
ATOM   709  C CG2 . VAL A 1 95  ? -14.24252 -3.29311 -24.61496 1.000 32.06833 ? 96  VAL A CG2 1 
ATOM   710  N N   . ALA A 1 96  ? -10.58731 -0.46225 -24.29880 1.000 24.26155 ? 97  ALA A N   1 
ATOM   711  C CA  . ALA A 1 96  ? -9.91843  0.82666  -24.45643 1.000 27.71006 ? 97  ALA A CA  1 
ATOM   712  C C   . ALA A 1 96  ? -10.62343 1.62547  -25.54856 1.000 23.96362 ? 97  ALA A C   1 
ATOM   713  O O   . ALA A 1 96  ? -10.88591 1.10119  -26.63348 1.000 25.22301 ? 97  ALA A O   1 
ATOM   714  C CB  . ALA A 1 96  ? -8.43829  0.63783  -24.80193 1.000 23.22521 ? 97  ALA A CB  1 
ATOM   715  N N   . ASN A 1 97  ? -10.94266 2.88646  -25.25693 1.000 24.70450 ? 98  ASN A N   1 
ATOM   716  C CA  . ASN A 1 97  ? -11.62709 3.72469  -26.23699 1.000 22.57043 ? 98  ASN A CA  1 
ATOM   717  C C   . ASN A 1 97  ? -10.79591 3.79319  -27.51427 1.000 21.47612 ? 98  ASN A C   1 
ATOM   718  O O   . ASN A 1 97  ? -9.66375  4.27844  -27.47541 1.000 24.22943 ? 98  ASN A O   1 
ATOM   719  C CB  . ASN A 1 97  ? -11.87217 5.12839  -25.68252 1.000 22.29122 ? 98  ASN A CB  1 
ATOM   720  C CG  . ASN A 1 97  ? -12.67205 6.00999  -26.64675 1.000 23.03766 ? 98  ASN A CG  1 
ATOM   721  O OD1 . ASN A 1 97  ? -12.94661 5.61827  -27.77273 1.000 23.01542 ? 98  ASN A OD1 1 
ATOM   722  N ND2 . ASN A 1 97  ? -13.03100 7.21769  -26.20184 1.000 21.65129 ? 98  ASN A ND2 1 
ATOM   723  N N   . PRO A 1 98  ? -11.30252 3.30243  -28.64925 1.000 23.08848 ? 99  PRO A N   1 
ATOM   724  C CA  . PRO A 1 98  ? -10.48744 3.28848  -29.87529 1.000 25.19196 ? 99  PRO A CA  1 
ATOM   725  C C   . PRO A 1 98  ? -10.32195 4.65657  -30.50193 1.000 27.72820 ? 99  PRO A C   1 
ATOM   726  O O   . PRO A 1 98  ? -9.54374  4.79332  -31.45439 1.000 28.25678 ? 99  PRO A O   1 
ATOM   727  C CB  . PRO A 1 98  ? -11.26383 2.34646  -30.80059 1.000 28.85225 ? 99  PRO A CB  1 
ATOM   728  C CG  . PRO A 1 98  ? -12.68318 2.45880  -30.33350 1.000 28.97641 ? 99  PRO A CG  1 
ATOM   729  C CD  . PRO A 1 98  ? -12.61765 2.66722  -28.84135 1.000 25.06179 ? 99  PRO A CD  1 
ATOM   730  N N   . SER A 1 99  ? -11.02458 5.66890  -29.99808 1.000 24.95377 ? 100 SER A N   1 
ATOM   731  C CA  . SER A 1 99  ? -10.91329 7.03066  -30.49634 1.000 28.20636 ? 100 SER A CA  1 
ATOM   732  C C   . SER A 1 99  ? -10.33472 7.97526  -29.44551 1.000 25.07694 ? 100 SER A C   1 
ATOM   733  O O   . SER A 1 99  ? -10.62659 9.16637  -29.45992 1.000 30.44928 ? 100 SER A O   1 
ATOM   734  C CB  . SER A 1 99  ? -12.27740 7.52879  -30.97324 1.000 27.20228 ? 100 SER A CB  1 
ATOM   735  O OG  . SER A 1 99  ? -12.76087 6.71082  -32.02848 1.000 34.43913 ? 100 SER A OG  1 
ATOM   736  N N   . THR A 1 100 ? -9.50878  7.46791  -28.53315 1.000 23.46415 ? 101 THR A N   1 
ATOM   737  C CA  . THR A 1 100 ? -8.88520  8.33319  -27.52244 1.000 22.24000 ? 101 THR A CA  1 
ATOM   738  C C   . THR A 1 100 ? -7.92862  9.30567  -28.19920 1.000 23.74128 ? 101 THR A C   1 
ATOM   739  O O   . THR A 1 100 ? -7.00848  8.86186  -28.90001 1.000 22.73271 ? 101 THR A O   1 
ATOM   740  C CB  . THR A 1 100 ? -8.13036  7.49615  -26.48100 1.000 24.10739 ? 101 THR A CB  1 
ATOM   741  O OG1 . THR A 1 100 ? -9.02134  6.55164  -25.87331 1.000 23.71419 ? 101 THR A OG1 1 
ATOM   742  C CG2 . THR A 1 100 ? -7.53988  8.37600  -25.38457 1.000 22.66291 ? 101 THR A CG2 1 
ATOM   743  N N   . PRO A 1 101 ? -8.08990  10.61936 -28.02199 1.000 22.29094 ? 102 PRO A N   1 
ATOM   744  C CA  . PRO A 1 101 ? -7.08937  11.55428 -28.53616 1.000 24.03013 ? 102 PRO A CA  1 
ATOM   745  C C   . PRO A 1 101 ? -5.83672  11.54273 -27.67693 1.000 20.30603 ? 102 PRO A C   1 
ATOM   746  O O   . PRO A 1 101 ? -5.84473  11.13914 -26.51620 1.000 23.14504 ? 102 PRO A O   1 
ATOM   747  C CB  . PRO A 1 101 ? -7.79694  12.91524 -28.46087 1.000 22.95262 ? 102 PRO A CB  1 
ATOM   748  C CG  . PRO A 1 101 ? -8.69353  12.77883 -27.23160 1.000 22.10803 ? 102 PRO A CG  1 
ATOM   749  C CD  . PRO A 1 101 ? -9.11646  11.29569 -27.19928 1.000 21.67917 ? 102 PRO A CD  1 
ATOM   750  N N   . ALA A 1 102 ? -4.73340  11.98126 -28.27570 1.000 22.12690 ? 103 ALA A N   1 
ATOM   751  C CA  . ALA A 1 102 ? -3.59644  12.40497 -27.47213 1.000 21.94717 ? 103 ALA A CA  1 
ATOM   752  C C   . ALA A 1 102 ? -4.05207  13.48046 -26.49302 1.000 22.74172 ? 103 ALA A C   1 
ATOM   753  O O   . ALA A 1 102 ? -4.74055  14.42800 -26.88438 1.000 21.52842 ? 103 ALA A O   1 
ATOM   754  C CB  . ALA A 1 102 ? -2.48699  12.94207 -28.37773 1.000 24.86279 ? 103 ALA A CB  1 
ATOM   755  N N   . TYR A 1 103 ? -3.68385  13.33136 -25.21656 1.000 20.47192 ? 104 TYR A N   1 
ATOM   756  C CA  . TYR A 1 103 ? -4.25933  14.21561 -24.20647 1.000 19.36743 ? 104 TYR A CA  1 
ATOM   757  C C   . TYR A 1 103 ? -3.31448  14.42063 -23.03366 1.000 20.92858 ? 104 TYR A C   1 
ATOM   758  O O   . TYR A 1 103 ? -2.43402  13.59654 -22.76259 1.000 23.26065 ? 104 TYR A O   1 
ATOM   759  C CB  . TYR A 1 103 ? -5.61076  13.67499 -23.70178 1.000 19.20516 ? 104 TYR A CB  1 
ATOM   760  C CG  . TYR A 1 103 ? -5.52049  12.52494 -22.71263 1.000 20.89015 ? 104 TYR A CG  1 
ATOM   761  C CD1 . TYR A 1 103 ? -5.40404  12.77217 -21.34303 1.000 21.45603 ? 104 TYR A CD1 1 
ATOM   762  C CD2 . TYR A 1 103 ? -5.58146  11.19636 -23.13990 1.000 21.35612 ? 104 TYR A CD2 1 
ATOM   763  C CE1 . TYR A 1 103 ? -5.32379  11.74067 -20.43056 1.000 23.38451 ? 104 TYR A CE1 1 
ATOM   764  C CE2 . TYR A 1 103 ? -5.49148  10.13642 -22.21666 1.000 21.38359 ? 104 TYR A CE2 1 
ATOM   765  C CZ  . TYR A 1 103 ? -5.36724  10.42684 -20.86778 1.000 23.73524 ? 104 TYR A CZ  1 
ATOM   766  O OH  . TYR A 1 103 ? -5.29398  9.43227  -19.91811 1.000 25.14089 ? 104 TYR A OH  1 
ATOM   767  N N   . THR A 1 104 ? -3.54307  15.53023 -22.31683 1.000 18.94686 ? 105 THR A N   1 
ATOM   768  C CA  . THR A 1 104 ? -2.90718  15.84406 -21.04601 1.000 21.81869 ? 105 THR A CA  1 
ATOM   769  C C   . THR A 1 104 ? -3.97133  16.35857 -20.07931 1.000 23.56670 ? 105 THR A C   1 
ATOM   770  O O   . THR A 1 104 ? -5.10374  16.66973 -20.46397 1.000 21.14862 ? 105 THR A O   1 
ATOM   771  C CB  . THR A 1 104 ? -1.78982  16.89742 -21.19993 1.000 25.85918 ? 105 THR A CB  1 
ATOM   772  O OG1 . THR A 1 104 ? -2.35514  18.14394 -21.63716 1.000 23.98204 ? 105 THR A OG1 1 
ATOM   773  C CG2 . THR A 1 104 ? -0.77791  16.46631 -22.25150 1.000 25.93927 ? 105 THR A CG2 1 
ATOM   774  N N   . PHE A 1 105 ? -3.59876  16.43267 -18.80563 1.000 22.57151 ? 106 PHE A N   1 
ATOM   775  C CA  . PHE A 1 105 ? -4.44031  16.97725 -17.74779 1.000 22.75429 ? 106 PHE A CA  1 
ATOM   776  C C   . PHE A 1 105 ? -3.67815  18.15954 -17.17668 1.000 32.80170 ? 106 PHE A C   1 
ATOM   777  O O   . PHE A 1 105 ? -2.66581  17.96787 -16.49482 1.000 39.39507 ? 106 PHE A O   1 
ATOM   778  C CB  . PHE A 1 105 ? -4.69662  15.96151 -16.63538 1.000 22.08743 ? 106 PHE A CB  1 
ATOM   779  C CG  . PHE A 1 105 ? -5.58261  14.80771 -17.02035 1.000 25.43382 ? 106 PHE A CG  1 
ATOM   780  C CD1 . PHE A 1 105 ? -6.56512  14.93766 -17.99456 1.000 20.61435 ? 106 PHE A CD1 1 
ATOM   781  C CD2 . PHE A 1 105 ? -5.46254  13.59553 -16.35353 1.000 23.87352 ? 106 PHE A CD2 1 
ATOM   782  C CE1 . PHE A 1 105 ? -7.40005  13.87318 -18.30503 1.000 21.84003 ? 106 PHE A CE1 1 
ATOM   783  C CE2 . PHE A 1 105 ? -6.29636  12.53150 -16.65850 1.000 23.52357 ? 106 PHE A CE2 1 
ATOM   784  C CZ  . PHE A 1 105 ? -7.26084  12.66306 -17.63441 1.000 21.79761 ? 106 PHE A CZ  1 
ATOM   785  N N   . THR A 1 106 ? -4.13895  19.37184 -17.43821 1.000 27.28519 ? 107 THR A N   1 
ATOM   786  C CA  . THR A 1 106 ? -3.52005  20.52859 -16.80470 1.000 28.52794 ? 107 THR A CA  1 
ATOM   787  C C   . THR A 1 106 ? -4.61034  21.43682 -16.27457 1.000 30.76468 ? 107 THR A C   1 
ATOM   788  O O   . THR A 1 106 ? -5.64830  21.62752 -16.91657 1.000 30.54462 ? 107 THR A O   1 
ATOM   789  C CB  . THR A 1 106 ? -2.58502  21.30858 -17.75820 1.000 36.78930 ? 107 THR A CB  1 
ATOM   790  O OG1 . THR A 1 106 ? -1.56432  20.43217 -18.25025 1.000 39.89372 ? 107 THR A OG1 1 
ATOM   791  C CG2 . THR A 1 106 ? -1.90183  22.46841 -17.03330 1.000 32.17721 ? 107 THR A CG2 1 
ATOM   792  N N   . THR A 1 107 ? -4.36927  21.96392 -15.08475 1.000 25.14837 ? 108 THR A N   1 
ATOM   793  C CA  . THR A 1 107 ? -5.27838  22.89521 -14.43853 1.000 27.14584 ? 108 THR A CA  1 
ATOM   794  C C   . THR A 1 107 ? -5.18246  24.27216 -15.09060 1.000 25.22288 ? 108 THR A C   1 
ATOM   795  O O   . THR A 1 107 ? -4.08166  24.76547 -15.35226 1.000 28.63010 ? 108 THR A O   1 
ATOM   796  C CB  . THR A 1 107 ? -4.91063  22.95227 -12.95766 1.000 28.46631 ? 108 THR A CB  1 
ATOM   797  O OG1 . THR A 1 107 ? -4.95835  21.61720 -12.43770 1.000 28.89960 ? 108 THR A OG1 1 
ATOM   798  C CG2 . THR A 1 107 ? -5.85562  23.84246 -12.16655 1.000 29.41376 ? 108 THR A CG2 1 
ATOM   799  N N   . VAL A 1 108 ? -6.33213  24.89847 -15.36518 1.000 24.40323 ? 109 VAL A N   1 
ATOM   800  C CA  . VAL A 1 108 ? -6.32492  26.24301 -15.93341 1.000 25.51512 ? 109 VAL A CA  1 
ATOM   801  C C   . VAL A 1 108 ? -6.29130  27.26624 -14.80732 1.000 27.86999 ? 109 VAL A C   1 
ATOM   802  O O   . VAL A 1 108 ? -6.68739  26.99428 -13.67505 1.000 26.22392 ? 109 VAL A O   1 
ATOM   803  C CB  . VAL A 1 108 ? -7.51804  26.50985 -16.87191 1.000 26.90997 ? 109 VAL A CB  1 
ATOM   804  C CG1 . VAL A 1 108 ? -7.32185  25.76975 -18.18883 1.000 34.20899 ? 109 VAL A CG1 1 
ATOM   805  C CG2 . VAL A 1 108 ? -8.83010  26.16320 -16.19788 1.000 24.48524 ? 109 VAL A CG2 1 
ATOM   806  N N   . LYS A 1 109 ? -5.80579  28.45822 -15.12905 1.000 25.98527 ? 110 LYS A N   1 
ATOM   807  C CA  . LYS A 1 109 ? -5.73076  29.56705 -14.19894 1.000 28.19683 ? 110 LYS A CA  1 
ATOM   808  C C   . LYS A 1 109 ? -6.78502  30.60883 -14.53773 1.000 25.36644 ? 110 LYS A C   1 
ATOM   809  O O   . LYS A 1 109 ? -7.31776  30.63685 -15.65333 1.000 24.80687 ? 110 LYS A O   1 
ATOM   810  C CB  . LYS A 1 109 ? -4.34213  30.21871 -14.22532 1.000 30.27093 ? 110 LYS A CB  1 
ATOM   811  C CG  . LYS A 1 109 ? -3.21114  29.21509 -14.33239 1.000 36.64334 ? 110 LYS A CG  1 
ATOM   812  C CD  . LYS A 1 109 ? -1.87711  29.91587 -14.18915 1.000 42.56417 ? 110 LYS A CD  1 
ATOM   813  C CE  . LYS A 1 109 ? -1.31820  29.73604 -12.79226 1.000 46.27163 ? 110 LYS A CE  1 
ATOM   814  N NZ  . LYS A 1 109 ? 0.14898   29.49629 -12.86299 1.000 54.04156 ? 110 LYS A NZ  1 
ATOM   815  N N   . PRO A 1 110 ? -7.11243  31.48307 -13.59551 1.000 24.00798 ? 111 PRO A N   1 
ATOM   816  C CA  . PRO A 1 110 ? -8.09290  32.53283 -13.87952 1.000 25.31590 ? 111 PRO A CA  1 
ATOM   817  C C   . PRO A 1 110 ? -7.69028  33.38985 -15.07058 1.000 24.35328 ? 111 PRO A C   1 
ATOM   818  O O   . PRO A 1 110 ? -6.51861  33.71426 -15.26187 1.000 25.57042 ? 111 PRO A O   1 
ATOM   819  C CB  . PRO A 1 110 ? -8.11012  33.34230 -12.58202 1.000 26.06707 ? 111 PRO A CB  1 
ATOM   820  C CG  . PRO A 1 110 ? -7.82707  32.31761 -11.55163 1.000 26.44794 ? 111 PRO A CG  1 
ATOM   821  C CD  . PRO A 1 110 ? -6.77921  31.43528 -12.16432 1.000 30.60518 ? 111 PRO A CD  1 
ATOM   822  N N   . GLY A 1 111 ? -8.68503  33.75581 -15.87433 1.000 24.30470 ? 112 GLY A N   1 
ATOM   823  C CA  . GLY A 1 111 ? -8.46052  34.50652 -17.08377 1.000 23.90270 ? 112 GLY A CA  1 
ATOM   824  C C   . GLY A 1 111 ? -8.22064  33.65689 -18.31547 1.000 23.90818 ? 112 GLY A C   1 
ATOM   825  O O   . GLY A 1 111 ? -8.41922  34.14468 -19.42565 1.000 23.12344 ? 112 GLY A O   1 
ATOM   826  N N   . ALA A 1 112 ? -7.80931  32.40108 -18.14964 1.000 20.18736 ? 113 ALA A N   1 
ATOM   827  C CA  . ALA A 1 112 ? -7.56461  31.53310 -19.29656 1.000 25.04788 ? 113 ALA A CA  1 
ATOM   828  C C   . ALA A 1 112 ? -8.87978  31.01775 -19.87839 1.000 22.67948 ? 113 ALA A C   1 
ATOM   829  O O   . ALA A 1 112 ? -9.84639  30.76522 -19.15374 1.000 23.77563 ? 113 ALA A O   1 
ATOM   830  C CB  . ALA A 1 112 ? -6.65900  30.36481 -18.89936 1.000 21.93370 ? 113 ALA A CB  1 
ATOM   831  N N   . ALA A 1 113 ? -8.90929  30.86692 -21.19507 1.000 21.39818 ? 114 ALA A N   1 
ATOM   832  C CA  . ALA A 1 113 ? -10.08747 30.42539 -21.93446 1.000 22.04021 ? 114 ALA A CA  1 
ATOM   833  C C   . ALA A 1 113 ? -10.00495 28.93969 -22.26169 1.000 21.31078 ? 114 ALA A C   1 
ATOM   834  O O   . ALA A 1 113 ? -8.92133  28.39769 -22.50724 1.000 20.61183 ? 114 ALA A O   1 
ATOM   835  C CB  . ALA A 1 113 ? -10.23117 31.20293 -23.24564 1.000 22.67354 ? 114 ALA A CB  1 
ATOM   836  N N   . PHE A 1 114 ? -11.16516 28.28175 -22.27762 1.000 20.51720 ? 115 PHE A N   1 
ATOM   837  C CA  . PHE A 1 114 ? -11.22279 26.91754 -22.78701 1.000 18.97290 ? 115 PHE A CA  1 
ATOM   838  C C   . PHE A 1 114 ? -12.59629 26.64524 -23.39085 1.000 20.87348 ? 115 PHE A C   1 
ATOM   839  O O   . PHE A 1 114 ? -13.56997 27.36634 -23.13824 1.000 20.25656 ? 115 PHE A O   1 
ATOM   840  C CB  . PHE A 1 114 ? -10.87426 25.88085 -21.71016 1.000 18.93618 ? 115 PHE A CB  1 
ATOM   841  C CG  . PHE A 1 114 ? -11.73072 25.93704 -20.45365 1.000 23.11244 ? 115 PHE A CG  1 
ATOM   842  C CD1 . PHE A 1 114 ? -11.37714 26.76827 -19.38961 1.000 22.54809 ? 115 PHE A CD1 1 
ATOM   843  C CD2 . PHE A 1 114 ? -12.84398 25.10833 -20.31033 1.000 18.79815 ? 115 PHE A CD2 1 
ATOM   844  C CE1 . PHE A 1 114 ? -12.13907 26.79171 -18.21102 1.000 22.67071 ? 115 PHE A CE1 1 
ATOM   845  C CE2 . PHE A 1 114 ? -13.60443 25.12187 -19.13145 1.000 21.57413 ? 115 PHE A CE2 1 
ATOM   846  C CZ  . PHE A 1 114 ? -13.24760 25.95928 -18.08148 1.000 19.54177 ? 115 PHE A CZ  1 
ATOM   847  N N   . SER A 1 115 ? -12.64968 25.61451 -24.22857 1.000 17.70158 ? 116 SER A N   1 
ATOM   848  C CA  . SER A 1 115 ? -13.88903 25.18805 -24.86016 1.000 18.02327 ? 116 SER A CA  1 
ATOM   849  C C   . SER A 1 115 ? -14.59158 24.16664 -23.97400 1.000 19.99029 ? 116 SER A C   1 
ATOM   850  O O   . SER A 1 115 ? -13.95028 23.36051 -23.29382 1.000 18.86511 ? 116 SER A O   1 
ATOM   851  C CB  . SER A 1 115 ? -13.61751 24.57558 -26.23700 1.000 21.00193 ? 116 SER A CB  1 
ATOM   852  O OG  . SER A 1 115 ? -13.04452 25.51420 -27.14730 1.000 20.42456 ? 116 SER A OG  1 
ATOM   853  N N   . VAL A 1 116 ? -15.91840 24.18889 -23.99911 1.000 20.72016 ? 117 VAL A N   1 
ATOM   854  C CA  . VAL A 1 116 ? -16.73116 23.27770 -23.20763 1.000 16.56344 ? 117 VAL A CA  1 
ATOM   855  C C   . VAL A 1 116 ? -17.66007 22.52808 -24.14825 1.000 18.49770 ? 117 VAL A C   1 
ATOM   856  O O   . VAL A 1 116 ? -18.27262 23.12791 -25.03463 1.000 18.26565 ? 117 VAL A O   1 
ATOM   857  C CB  . VAL A 1 116 ? -17.54175 24.02173 -22.13198 1.000 19.91799 ? 117 VAL A CB  1 
ATOM   858  C CG1 . VAL A 1 116 ? -18.50712 23.05431 -21.46348 1.000 20.32105 ? 117 VAL A CG1 1 
ATOM   859  C CG2 . VAL A 1 116 ? -16.62490 24.63982 -21.10359 1.000 22.24770 ? 117 VAL A CG2 1 
ATOM   860  N N   . LEU A 1 117 ? -17.76215 21.22723 -23.96554 1.000 20.91724 ? 118 LEU A N   1 
ATOM   861  C CA  . LEU A 1 117 ? -18.71361 20.42142 -24.71207 1.000 19.26319 ? 118 LEU A CA  1 
ATOM   862  C C   . LEU A 1 117 ? -19.83175 20.05419 -23.74397 1.000 21.61442 ? 118 LEU A C   1 
ATOM   863  O O   . LEU A 1 117 ? -19.64263 19.21586 -22.85473 1.000 21.35926 ? 118 LEU A O   1 
ATOM   864  C CB  . LEU A 1 117 ? -18.04886 19.18236 -25.30288 1.000 20.04885 ? 118 LEU A CB  1 
ATOM   865  C CG  . LEU A 1 117 ? -19.03188 18.28786 -26.06968 1.000 18.81541 ? 118 LEU A CG  1 
ATOM   866  C CD1 . LEU A 1 117 ? -19.60850 19.06214 -27.26206 1.000 21.22940 ? 118 LEU A CD1 1 
ATOM   867  C CD2 . LEU A 1 117 ? -18.33691 17.01747 -26.54010 1.000 20.39808 ? 118 LEU A CD2 1 
ATOM   868  N N   . ALA A 1 118 ? -20.99168 20.67272 -23.91245 1.000 21.11813 ? 119 ALA A N   1 
ATOM   869  C CA  . ALA A 1 118 ? -22.11673 20.39163 -23.02708 1.000 23.80344 ? 119 ALA A CA  1 
ATOM   870  C C   . ALA A 1 118 ? -22.82925 19.11806 -23.47380 1.000 22.94582 ? 119 ALA A C   1 
ATOM   871  O O   . ALA A 1 118 ? -23.15821 18.96883 -24.65173 1.000 22.39362 ? 119 ALA A O   1 
ATOM   872  C CB  . ALA A 1 118 ? -23.08159 21.57604 -23.01262 1.000 20.69956 ? 119 ALA A CB  1 
ATOM   873  N N   . CYS A 1 119 ? -23.07332 18.20336 -22.53033 1.000 22.48505 ? 120 CYS A N   1 
ATOM   874  C CA  . CYS A 1 119 ? -23.68265 16.90643 -22.80835 1.000 19.43622 ? 120 CYS A CA  1 
ATOM   875  C C   . CYS A 1 119 ? -24.76774 16.58008 -21.78896 1.000 22.26983 ? 120 CYS A C   1 
ATOM   876  O O   . CYS A 1 119 ? -24.71398 16.99911 -20.63088 1.000 22.73713 ? 120 CYS A O   1 
ATOM   877  C CB  . CYS A 1 119 ? -22.65579 15.75604 -22.77846 1.000 22.06534 ? 120 CYS A CB  1 
ATOM   878  S SG  . CYS A 1 119 ? -21.22040 15.98548 -23.83381 1.000 29.06546 ? 120 CYS A SG  1 
ATOM   879  N N   . TYR A 1 120 ? -25.74873 15.80716 -22.23504 1.000 23.53166 ? 121 TYR A N   1 
ATOM   880  C CA  . TYR A 1 120 ? -26.85921 15.37922 -21.39384 1.000 24.13171 ? 121 TYR A CA  1 
ATOM   881  C C   . TYR A 1 120 ? -27.10085 13.91021 -21.68533 1.000 23.92799 ? 121 TYR A C   1 
ATOM   882  O O   . TYR A 1 120 ? -27.24227 13.53111 -22.85069 1.000 24.21109 ? 121 TYR A O   1 
ATOM   883  C CB  . TYR A 1 120 ? -28.10514 16.23596 -21.66894 1.000 24.00458 ? 121 TYR A CB  1 
ATOM   884  C CG  . TYR A 1 120 ? -27.84822 17.68224 -21.30389 1.000 24.39469 ? 121 TYR A CG  1 
ATOM   885  C CD1 . TYR A 1 120 ? -28.02336 18.12698 -20.00183 1.000 24.76508 ? 121 TYR A CD1 1 
ATOM   886  C CD2 . TYR A 1 120 ? -27.35453 18.58198 -22.24660 1.000 23.52915 ? 121 TYR A CD2 1 
ATOM   887  C CE1 . TYR A 1 120 ? -27.74704 19.43884 -19.64262 1.000 24.03525 ? 121 TYR A CE1 1 
ATOM   888  C CE2 . TYR A 1 120 ? -27.07499 19.90048 -21.90720 1.000 25.64037 ? 121 TYR A CE2 1 
ATOM   889  C CZ  . TYR A 1 120 ? -27.27759 20.32351 -20.60317 1.000 24.29347 ? 121 TYR A CZ  1 
ATOM   890  O OH  . TYR A 1 120 ? -27.00299 21.61714 -20.26838 1.000 27.13808 ? 121 TYR A OH  1 
ATOM   891  N N   . ASN A 1 121 ? -27.08480 13.08089 -20.63629 1.000 24.89399 ? 122 ASN A N   1 
ATOM   892  C CA  . ASN A 1 121 ? -27.23921 11.63559 -20.78202 1.000 27.49933 ? 122 ASN A CA  1 
ATOM   893  C C   . ASN A 1 121 ? -26.24776 11.07333 -21.79231 1.000 27.06246 ? 122 ASN A C   1 
ATOM   894  O O   . ASN A 1 121 ? -26.57365 10.19872 -22.59522 1.000 25.87064 ? 122 ASN A O   1 
ATOM   895  C CB  . ASN A 1 121 ? -28.66597 11.28500 -21.17707 1.000 26.77573 ? 122 ASN A CB  1 
ATOM   896  C CG  . ASN A 1 121 ? -29.67214 11.97146 -20.30990 1.000 33.75811 ? 122 ASN A CG  1 
ATOM   897  O OD1 . ASN A 1 121 ? -29.72532 11.71884 -19.10745 1.000 34.08002 ? 122 ASN A OD1 1 
ATOM   898  N ND2 . ASN A 1 121 ? -30.46708 12.86302 -20.89930 1.000 33.62713 ? 122 ASN A ND2 1 
ATOM   899  N N   . GLY A 1 122 ? -25.03376 11.60809 -21.77875 1.000 24.32264 ? 123 GLY A N   1 
ATOM   900  C CA  . GLY A 1 122 ? -24.00874 11.11787 -22.67708 1.000 25.16147 ? 123 GLY A CA  1 
ATOM   901  C C   . GLY A 1 122 ? -24.12320 11.56271 -24.11347 1.000 22.93961 ? 123 GLY A C   1 
ATOM   902  O O   . GLY A 1 122 ? -23.37808 11.05391 -24.96197 1.000 27.57608 ? 123 GLY A O   1 
ATOM   903  N N   . ARG A 1 123 ? -25.01869 12.49899 -24.42393 1.000 23.37365 ? 124 ARG A N   1 
ATOM   904  C CA  . ARG A 1 123 ? -25.16606 13.00563 -25.78034 1.000 23.76388 ? 124 ARG A CA  1 
ATOM   905  C C   . ARG A 1 123 ? -24.68341 14.44338 -25.82515 1.000 24.24996 ? 124 ARG A C   1 
ATOM   906  O O   . ARG A 1 123 ? -25.23205 15.29201 -25.10393 1.000 22.29974 ? 124 ARG A O   1 
ATOM   907  C CB  . ARG A 1 123 ? -26.61874 12.92641 -26.26150 1.000 28.47238 ? 124 ARG A CB  1 
ATOM   908  C CG  . ARG A 1 123 ? -27.09212 11.49904 -26.56329 1.000 34.67451 ? 124 ARG A CG  1 
ATOM   909  C CD  . ARG A 1 123 ? -28.24863 11.47717 -27.57671 1.000 41.50454 ? 124 ARG A CD  1 
ATOM   910  N NE  . ARG A 1 123 ? -28.34441 10.17451 -28.23953 1.000 51.11287 ? 124 ARG A NE  1 
ATOM   911  C CZ  . ARG A 1 123 ? -28.79252 9.06966  -27.64489 1.000 47.67996 ? 124 ARG A CZ  1 
ATOM   912  N NH1 . ARG A 1 123 ? -29.18844 9.10724  -26.37531 1.000 40.74728 ? 124 ARG A NH1 1 
ATOM   913  N NH2 . ARG A 1 123 ? -28.84425 7.92350  -28.31408 1.000 47.58547 ? 124 ARG A NH2 1 
ATOM   914  N N   . PRO A 1 124 ? -23.67384 14.75615 -26.63406 1.000 22.38643 ? 125 PRO A N   1 
ATOM   915  C CA  . PRO A 1 124 ? -23.27211 16.16108 -26.81818 1.000 21.89879 ? 125 PRO A CA  1 
ATOM   916  C C   . PRO A 1 124 ? -24.39799 16.97412 -27.43936 1.000 23.55237 ? 125 PRO A C   1 
ATOM   917  O O   . PRO A 1 124 ? -25.00984 16.55765 -28.42051 1.000 22.61585 ? 125 PRO A O   1 
ATOM   918  C CB  . PRO A 1 124 ? -22.06912 16.06722 -27.76765 1.000 23.08552 ? 125 PRO A CB  1 
ATOM   919  C CG  . PRO A 1 124 ? -21.56509 14.65161 -27.61923 1.000 25.22302 ? 125 PRO A CG  1 
ATOM   920  C CD  . PRO A 1 124 ? -22.78454 13.81824 -27.33679 1.000 26.51452 ? 125 PRO A CD  1 
ATOM   921  N N   . THR A 1 125 ? -24.66685 18.15116 -26.86756 1.000 23.15853 ? 126 THR A N   1 
ATOM   922  C CA  . THR A 1 125 ? -25.70534 19.02001 -27.40891 1.000 21.74689 ? 126 THR A CA  1 
ATOM   923  C C   . THR A 1 125 ? -25.24102 20.42487 -27.77141 1.000 22.18042 ? 126 THR A C   1 
ATOM   924  O O   . THR A 1 125 ? -25.90879 21.08138 -28.57203 1.000 21.71922 ? 126 THR A O   1 
ATOM   925  C CB  . THR A 1 125 ? -26.89357 19.13623 -26.43449 1.000 27.05518 ? 126 THR A CB  1 
ATOM   926  O OG1 . THR A 1 125 ? -26.46038 19.71140 -25.19818 1.000 26.69978 ? 126 THR A OG1 1 
ATOM   927  C CG2 . THR A 1 125 ? -27.51234 17.76433 -26.18179 1.000 23.57446 ? 126 THR A CG2 1 
ATOM   928  N N   . GLY A 1 126 ? -24.14514 20.91475 -27.21449 1.000 21.22346 ? 127 GLY A N   1 
ATOM   929  C CA  . GLY A 1 126 ? -23.68783 22.24076 -27.60041 1.000 21.39199 ? 127 GLY A CA  1 
ATOM   930  C C   . GLY A 1 126 ? -22.25897 22.43092 -27.15969 1.000 22.14906 ? 127 GLY A C   1 
ATOM   931  O O   . GLY A 1 126 ? -21.74670 21.67487 -26.32557 1.000 21.26470 ? 127 GLY A O   1 
ATOM   932  N N   . THR A 1 127 ? -21.60655 23.43089 -27.75761 1.000 20.55843 ? 128 THR A N   1 
ATOM   933  C CA  . THR A 1 127 ? -20.26008 23.81814 -27.37746 1.000 21.12813 ? 128 THR A CA  1 
ATOM   934  C C   . THR A 1 127 ? -20.18850 25.33690 -27.29200 1.000 22.35495 ? 128 THR A C   1 
ATOM   935  O O   . THR A 1 127 ? -20.88814 26.06566 -28.01096 1.000 20.68900 ? 128 THR A O   1 
ATOM   936  C CB  . THR A 1 127 ? -19.19657 23.25756 -28.35744 1.000 23.89001 ? 128 THR A CB  1 
ATOM   937  O OG1 . THR A 1 127 ? -17.88304 23.42942 -27.79697 1.000 27.47067 ? 128 THR A OG1 1 
ATOM   938  C CG2 . THR A 1 127 ? -19.25308 23.96661 -29.70860 1.000 22.71704 ? 128 THR A CG2 1 
ATOM   939  N N   . PHE A 1 128 ? -19.34180 25.80125 -26.38765 1.000 19.59158 ? 129 PHE A N   1 
ATOM   940  C CA  . PHE A 1 128 ? -19.13641 27.22187 -26.16242 1.000 23.21116 ? 129 PHE A CA  1 
ATOM   941  C C   . PHE A 1 128 ? -17.78357 27.37798 -25.49022 1.000 22.86156 ? 129 PHE A C   1 
ATOM   942  O O   . PHE A 1 128 ? -17.15168 26.39986 -25.06921 1.000 21.79668 ? 129 PHE A O   1 
ATOM   943  C CB  . PHE A 1 128 ? -20.25981 27.84733 -25.30771 1.000 19.76524 ? 129 PHE A CB  1 
ATOM   944  C CG  . PHE A 1 128 ? -20.60556 27.04857 -24.06123 1.000 20.52062 ? 129 PHE A CG  1 
ATOM   945  C CD1 . PHE A 1 128 ? -19.92396 27.25415 -22.85969 1.000 21.86921 ? 129 PHE A CD1 1 
ATOM   946  C CD2 . PHE A 1 128 ? -21.62335 26.10981 -24.09141 1.000 24.77881 ? 129 PHE A CD2 1 
ATOM   947  C CE1 . PHE A 1 128 ? -20.25171 26.49990 -21.69681 1.000 22.40686 ? 129 PHE A CE1 1 
ATOM   948  C CE2 . PHE A 1 128 ? -21.95440 25.36981 -22.95282 1.000 24.23277 ? 129 PHE A CE2 1 
ATOM   949  C CZ  . PHE A 1 128 ? -21.26880 25.57754 -21.75661 1.000 23.44194 ? 129 PHE A CZ  1 
ATOM   950  N N   . THR A 1 129 ? -17.35421 28.62397 -25.37760 1.000 18.19291 ? 130 THR A N   1 
ATOM   951  C CA  . THR A 1 129 ? -16.06426 28.93325 -24.79314 1.000 20.42011 ? 130 THR A CA  1 
ATOM   952  C C   . THR A 1 129 ? -16.28101 29.81174 -23.56829 1.000 23.22983 ? 130 THR A C   1 
ATOM   953  O O   . THR A 1 129 ? -17.16987 30.67631 -23.55071 1.000 22.53726 ? 130 THR A O   1 
ATOM   954  C CB  . THR A 1 129 ? -15.14046 29.60181 -25.83276 1.000 21.37144 ? 130 THR A CB  1 
ATOM   955  O OG1 . THR A 1 129 ? -13.84900 29.80811 -25.26153 1.000 26.53327 ? 130 THR A OG1 1 
ATOM   956  C CG2 . THR A 1 129 ? -15.68399 30.97640 -26.25163 1.000 27.90288 ? 130 THR A CG2 1 
ATOM   957  N N   . VAL A 1 130 ? -15.50112 29.54634 -22.52409 1.000 21.51273 ? 131 VAL A N   1 
ATOM   958  C CA  . VAL A 1 130 ? -15.60467 30.24648 -21.25201 1.000 23.63257 ? 131 VAL A CA  1 
ATOM   959  C C   . VAL A 1 130 ? -14.20594 30.69056 -20.84853 1.000 24.33936 ? 131 VAL A C   1 
ATOM   960  O O   . VAL A 1 130 ? -13.20950 30.27903 -21.44203 1.000 22.89279 ? 131 VAL A O   1 
ATOM   961  C CB  . VAL A 1 130 ? -16.23543 29.36126 -20.15390 1.000 24.99874 ? 131 VAL A CB  1 
ATOM   962  C CG1 . VAL A 1 130 ? -17.63036 28.91467 -20.56807 1.000 25.44306 ? 131 VAL A CG1 1 
ATOM   963  C CG2 . VAL A 1 130 ? -15.35539 28.13011 -19.88670 1.000 21.62233 ? 131 VAL A CG2 1 
ATOM   964  N N   . VAL A 1 131 ? -14.13679 31.55087 -19.83459 1.000 22.19199 ? 132 VAL A N   1 
ATOM   965  C CA  . VAL A 1 131 ? -12.87893 31.82472 -19.15156 1.000 22.56860 ? 132 VAL A CA  1 
ATOM   966  C C   . VAL A 1 131 ? -13.05265 31.44908 -17.68492 1.000 21.24989 ? 132 VAL A C   1 
ATOM   967  O O   . VAL A 1 131 ? -14.12357 31.65172 -17.10302 1.000 21.31830 ? 132 VAL A O   1 
ATOM   968  C CB  . VAL A 1 131 ? -12.42400 33.29599 -19.29980 1.000 27.63493 ? 132 VAL A CB  1 
ATOM   969  C CG1 . VAL A 1 131 ? -12.14853 33.65005 -20.75866 1.000 25.95814 ? 132 VAL A CG1 1 
ATOM   970  C CG2 . VAL A 1 131 ? -13.44872 34.22884 -18.73077 1.000 31.82889 ? 132 VAL A CG2 1 
ATOM   971  N N   . MET A 1 132 ? -12.01131 30.87018 -17.10032 1.000 20.16840 ? 133 MET A N   1 
ATOM   972  C CA  . MET A 1 132 ? -12.01785 30.60404 -15.67196 1.000 22.78223 ? 133 MET A CA  1 
ATOM   973  C C   . MET A 1 132 ? -12.03663 31.94586 -14.94955 1.000 23.92325 ? 133 MET A C   1 
ATOM   974  O O   . MET A 1 132 ? -11.13031 32.76082 -15.14530 1.000 24.67789 ? 133 MET A O   1 
ATOM   975  C CB  . MET A 1 132 ? -10.79219 29.77704 -15.28547 1.000 20.49365 ? 133 MET A CB  1 
ATOM   976  C CG  . MET A 1 132 ? -10.70581 29.42600 -13.79808 1.000 22.79699 ? 133 MET A CG  1 
ATOM   977  S SD  . MET A 1 132 ? -12.18990 28.64337 -13.16247 1.000 25.35912 ? 133 MET A SD  1 
ATOM   978  C CE  . MET A 1 132 ? -12.07625 27.05740 -14.02657 1.000 22.90144 ? 133 MET A CE  1 
ATOM   979  N N   . ARG A 1 133 ? -13.10321 32.21509 -14.18991 1.000 24.20316 ? 134 ARG A N   1 
ATOM   980  C CA  . ARG A 1 133 ? -13.25053 33.51417 -13.55038 1.000 22.77136 ? 134 ARG A CA  1 
ATOM   981  C C   . ARG A 1 133 ? -12.25543 33.64893 -12.39966 1.000 23.79535 ? 134 ARG A C   1 
ATOM   982  O O   . ARG A 1 133 ? -11.78748 32.65497 -11.84699 1.000 23.28146 ? 134 ARG A O   1 
ATOM   983  C CB  . ARG A 1 133 ? -14.67758 33.71928 -13.02789 1.000 24.81129 ? 134 ARG A CB  1 
ATOM   984  C CG  . ARG A 1 133 ? -15.78672 33.72542 -14.09537 1.000 25.66130 ? 134 ARG A CG  1 
ATOM   985  C CD  . ARG A 1 133 ? -15.53245 34.71941 -15.24302 1.000 26.96851 ? 134 ARG A CD  1 
ATOM   986  N NE  . ARG A 1 133 ? -15.19974 36.05623 -14.73982 1.000 29.45596 ? 134 ARG A NE  1 
ATOM   987  C CZ  . ARG A 1 133 ? -14.87825 37.09196 -15.50988 1.000 28.74131 ? 134 ARG A CZ  1 
ATOM   988  N NH1 . ARG A 1 133 ? -14.85629 36.96101 -16.83700 1.000 29.38374 ? 134 ARG A NH1 1 
ATOM   989  N NH2 . ARG A 1 133 ? -14.56587 38.26106 -14.95902 1.000 25.24913 ? 134 ARG A NH2 1 
ATOM   990  N N   . PRO A 1 134 ? -11.91287 34.87920 -12.02499 1.000 25.43718 ? 135 PRO A N   1 
ATOM   991  C CA  . PRO A 1 134 ? -11.03818 35.06898 -10.85678 1.000 25.87815 ? 135 PRO A CA  1 
ATOM   992  C C   . PRO A 1 134 ? -11.54936 34.42663 -9.56603  1.000 27.48833 ? 135 PRO A C   1 
ATOM   993  O O   . PRO A 1 134 ? -10.72779 34.07807 -8.71419  1.000 28.06897 ? 135 PRO A O   1 
ATOM   994  C CB  . PRO A 1 134 ? -10.95992 36.59927 -10.74148 1.000 27.61236 ? 135 PRO A CB  1 
ATOM   995  C CG  . PRO A 1 134 ? -11.10488 37.06475 -12.15461 1.000 27.09453 ? 135 PRO A CG  1 
ATOM   996  C CD  . PRO A 1 134 ? -12.11363 36.13143 -12.77735 1.000 27.31609 ? 135 PRO A CD  1 
ATOM   997  N N   . ASN A 1 135 ? -12.85850 34.24691 -9.38812  1.000 24.25932 ? 136 ASN A N   1 
ATOM   998  C CA  . ASN A 1 135 ? -13.38302 33.53808 -8.22275  1.000 28.09994 ? 136 ASN A CA  1 
ATOM   999  C C   . ASN A 1 135 ? -13.56796 32.04271 -8.46969  1.000 28.62367 ? 136 ASN A C   1 
ATOM   1000 O O   . ASN A 1 135 ? -14.30961 31.39001 -7.72126  1.000 28.53010 ? 136 ASN A O   1 
ATOM   1001 C CB  . ASN A 1 135 ? -14.70999 34.15169 -7.77540  1.000 31.71983 ? 136 ASN A CB  1 
ATOM   1002 C CG  . ASN A 1 135 ? -15.79804 33.98714 -8.81177  1.000 31.60869 ? 136 ASN A CG  1 
ATOM   1003 O OD1 . ASN A 1 135 ? -15.55318 33.47297 -9.90717  1.000 29.13345 ? 136 ASN A OD1 1 
ATOM   1004 N ND2 . ASN A 1 135 ? -17.00249 34.44234 -8.48679  1.000 31.78680 ? 136 ASN A ND2 1 
ATOM   1005 N N   . TYR A 1 136 ? -12.93594 31.50251 -9.51828  1.000 24.05514 ? 137 TYR A N   1 
ATOM   1006 C CA  . TYR A 1 136 ? -12.85916 30.05825 -9.77154  1.000 26.05708 ? 137 TYR A CA  1 
ATOM   1007 C C   . TYR A 1 136 ? -14.22473 29.46239 -10.06485 1.000 29.13188 ? 137 TYR A C   1 
ATOM   1008 O O   . TYR A 1 136 ? -14.52756 28.33501 -9.67621  1.000 30.59951 ? 137 TYR A O   1 
ATOM   1009 C CB  . TYR A 1 136 ? -12.18082 29.32234 -8.61950  1.000 27.46163 ? 137 TYR A CB  1 
ATOM   1010 C CG  . TYR A 1 136 ? -10.73930 29.70354 -8.52633  1.000 31.72010 ? 137 TYR A CG  1 
ATOM   1011 C CD1 . TYR A 1 136 ? -9.78108  29.07283 -9.30752  1.000 28.57334 ? 137 TYR A CD1 1 
ATOM   1012 C CD2 . TYR A 1 136 ? -10.33698 30.73802 -7.68852  1.000 32.55494 ? 137 TYR A CD2 1 
ATOM   1013 C CE1 . TYR A 1 136 ? -8.46095  29.44896 -9.23846  1.000 31.49336 ? 137 TYR A CE1 1 
ATOM   1014 C CE2 . TYR A 1 136 ? -9.02663  31.11675 -7.61043  1.000 33.83886 ? 137 TYR A CE2 1 
ATOM   1015 C CZ  . TYR A 1 136 ? -8.09289  30.47883 -8.38673  1.000 34.02869 ? 137 TYR A CZ  1 
ATOM   1016 O OH  . TYR A 1 136 ? -6.78364  30.88151 -8.28715  1.000 40.01921 ? 137 TYR A OH  1 
ATOM   1017 N N   . THR A 1 137 ? -15.04643 30.23026 -10.75576 1.000 27.72681 ? 138 THR A N   1 
ATOM   1018 C CA  . THR A 1 137 ? -16.29270 29.78625 -11.34249 1.000 27.29280 ? 138 THR A CA  1 
ATOM   1019 C C   . THR A 1 137 ? -16.24218 30.01796 -12.85015 1.000 27.15903 ? 138 THR A C   1 
ATOM   1020 O O   . THR A 1 137 ? -15.33593 30.67681 -13.37155 1.000 24.33602 ? 138 THR A O   1 
ATOM   1021 C CB  . THR A 1 137 ? -17.46169 30.55144 -10.73463 1.000 26.91912 ? 138 THR A CB  1 
ATOM   1022 O OG1 . THR A 1 137 ? -17.39532 31.93222 -11.13709 1.000 29.49916 ? 138 THR A OG1 1 
ATOM   1023 C CG2 . THR A 1 137 ? -17.45056 30.45671 -9.19458  1.000 30.52180 ? 138 THR A CG2 1 
ATOM   1024 N N   . ILE A 1 138 ? -17.21602 29.46527 -13.57174 1.000 26.56034 ? 139 ILE A N   1 
ATOM   1025 C CA  . ILE A 1 138 ? -17.36133 29.78761 -14.98538 1.000 25.37386 ? 139 ILE A CA  1 
ATOM   1026 C C   . ILE A 1 138 ? -18.83150 30.04577 -15.26236 1.000 28.25463 ? 139 ILE A C   1 
ATOM   1027 O O   . ILE A 1 138 ? -19.71476 29.58337 -14.53692 1.000 30.91750 ? 139 ILE A O   1 
ATOM   1028 C CB  . ILE A 1 138 ? -16.82708 28.68540 -15.94132 1.000 27.40911 ? 139 ILE A CB  1 
ATOM   1029 C CG1 . ILE A 1 138 ? -17.69827 27.42602 -15.86958 1.000 24.91556 ? 139 ILE A CG1 1 
ATOM   1030 C CG2 . ILE A 1 138 ? -15.34979 28.36501 -15.67683 1.000 24.26789 ? 139 ILE A CG2 1 
ATOM   1031 C CD1 . ILE A 1 138 ? -17.33733 26.38050 -16.96387 1.000 26.31352 ? 139 ILE A CD1 1 
ATOM   1032 N N   . LYS A 1 139 ? -19.07820 30.78149 -16.34276 1.000 27.87959 ? 140 LYS A N   1 
ATOM   1033 C CA  . LYS A 1 139 ? -20.41679 31.18028 -16.77579 1.000 36.39759 ? 140 LYS A CA  1 
ATOM   1034 C C   . LYS A 1 139 ? -20.62323 30.64277 -18.18548 1.000 38.24262 ? 140 LYS A C   1 
ATOM   1035 O O   . LYS A 1 139 ? -20.30034 31.30217 -19.17821 1.000 47.93852 ? 140 LYS A O   1 
ATOM   1036 C CB  . LYS A 1 139 ? -20.60141 32.68866 -16.76940 1.000 38.20698 ? 140 LYS A CB  1 
ATOM   1037 C CG  . LYS A 1 139 ? -19.90942 33.43142 -15.64958 1.000 32.72015 ? 140 LYS A CG  1 
ATOM   1038 C CD  . LYS A 1 139 ? -19.90937 34.93231 -15.96723 1.000 42.83553 ? 140 LYS A CD  1 
ATOM   1039 C CE  . LYS A 1 139 ? -19.49976 35.76632 -14.76279 1.000 40.19614 ? 140 LYS A CE  1 
ATOM   1040 N NZ  . LYS A 1 139 ? -19.15972 37.17447 -15.15900 1.000 46.28931 ? 140 LYS A NZ  1 
ATOM   1041 N N   . GLY A 1 140 ? -21.15829 29.44935 -18.27866 1.000 35.43331 ? 141 GLY A N   1 
ATOM   1042 C CA  . GLY A 1 140 ? -21.54625 28.98813 -19.58696 1.000 31.65060 ? 141 GLY A CA  1 
ATOM   1043 C C   . GLY A 1 140 ? -23.03038 28.73690 -19.55313 1.000 30.81484 ? 141 GLY A C   1 
ATOM   1044 O O   . GLY A 1 140 ? -23.75289 29.39692 -18.80236 1.000 33.12143 ? 141 GLY A O   1 
ATOM   1045 N N   . SER A 1 141 ? -23.49666 27.78116 -20.33794 1.000 28.11401 ? 142 SER A N   1 
ATOM   1046 C CA  . SER A 1 141 ? -24.88780 27.35733 -20.29984 1.000 30.51342 ? 142 SER A CA  1 
ATOM   1047 C C   . SER A 1 141 ? -24.88710 25.90134 -19.86286 1.000 29.44287 ? 142 SER A C   1 
ATOM   1048 O O   . SER A 1 141 ? -24.50097 25.01699 -20.63162 1.000 26.10135 ? 142 SER A O   1 
ATOM   1049 C CB  . SER A 1 141 ? -25.56456 27.53802 -21.65291 1.000 31.00897 ? 142 SER A CB  1 
ATOM   1050 O OG  . SER A 1 141 ? -26.95358 27.30056 -21.54404 1.000 33.05339 ? 142 SER A OG  1 
ATOM   1051 N N   . PHE A 1 142 ? -25.27666 25.65709 -18.61904 1.000 26.73717 ? 143 PHE A N   1 
ATOM   1052 C CA  . PHE A 1 142 ? -25.29790 24.31054 -18.06218 1.000 26.34276 ? 143 PHE A CA  1 
ATOM   1053 C C   . PHE A 1 142 ? -26.67370 24.10890 -17.45173 1.000 29.52324 ? 143 PHE A C   1 
ATOM   1054 O O   . PHE A 1 142 ? -27.07178 24.87280 -16.56518 1.000 30.47206 ? 143 PHE A O   1 
ATOM   1055 C CB  . PHE A 1 142 ? -24.21029 24.11724 -16.99310 1.000 24.61006 ? 143 PHE A CB  1 
ATOM   1056 C CG  . PHE A 1 142 ? -22.77108 24.19632 -17.51499 1.000 27.60486 ? 143 PHE A CG  1 
ATOM   1057 C CD1 . PHE A 1 142 ? -22.12846 23.06946 -18.00684 1.000 25.76787 ? 143 PHE A CD1 1 
ATOM   1058 C CD2 . PHE A 1 142 ? -22.05975 25.39205 -17.46707 1.000 29.05582 ? 143 PHE A CD2 1 
ATOM   1059 C CE1 . PHE A 1 142 ? -20.79855 23.12340 -18.46535 1.000 22.16875 ? 143 PHE A CE1 1 
ATOM   1060 C CE2 . PHE A 1 142 ? -20.72908 25.46316 -17.92696 1.000 26.65192 ? 143 PHE A CE2 1 
ATOM   1061 C CZ  . PHE A 1 142 ? -20.09926 24.31735 -18.42372 1.000 22.87481 ? 143 PHE A CZ  1 
ATOM   1062 N N   . LEU A 1 143 ? -27.40119 23.10515 -17.93579 1.000 26.35621 ? 144 LEU A N   1 
ATOM   1063 C CA  . LEU A 1 143 ? -28.70877 22.74615 -17.40875 1.000 29.40629 ? 144 LEU A CA  1 
ATOM   1064 C C   . LEU A 1 143 ? -28.60248 21.45403 -16.60552 1.000 29.54835 ? 144 LEU A C   1 
ATOM   1065 O O   . LEU A 1 143 ? -27.53011 20.85792 -16.48324 1.000 26.19253 ? 144 LEU A O   1 
ATOM   1066 C CB  . LEU A 1 143 ? -29.72574 22.60033 -18.53826 1.000 30.08366 ? 144 LEU A CB  1 
ATOM   1067 C CG  . LEU A 1 143 ? -30.34353 23.86808 -19.14744 1.000 35.07340 ? 144 LEU A CG  1 
ATOM   1068 C CD1 . LEU A 1 143 ? -29.80058 25.16962 -18.55877 1.000 36.52942 ? 144 LEU A CD1 1 
ATOM   1069 C CD2 . LEU A 1 143 ? -30.16143 23.82268 -20.64808 1.000 37.42848 ? 144 LEU A CD2 1 
ATOM   1070 N N   . CYS A 1 144 ? -29.73577 21.03420 -16.03489 1.000 31.33446 ? 145 CYS A N   1 
ATOM   1071 C CA  . CYS A 1 144 ? -29.78574 19.80710 -15.24307 1.000 29.59892 ? 145 CYS A CA  1 
ATOM   1072 C C   . CYS A 1 144 ? -29.27024 18.61470 -16.03811 1.000 25.18798 ? 145 CYS A C   1 
ATOM   1073 O O   . CYS A 1 144 ? -29.63571 18.42493 -17.19786 1.000 28.24184 ? 145 CYS A O   1 
ATOM   1074 C CB  . CYS A 1 144 ? -31.22241 19.55413 -14.78329 1.000 32.25962 ? 145 CYS A CB  1 
ATOM   1075 S SG  . CYS A 1 144 ? -31.63685 20.62875 -13.39444 1.000 43.15455 ? 145 CYS A SG  1 
ATOM   1076 N N   . GLY A 1 145 ? -28.42172 17.80521 -15.40431 1.000 27.02186 ? 146 GLY A N   1 
ATOM   1077 C CA  . GLY A 1 145 ? -27.84575 16.63948 -16.05321 1.000 26.04625 ? 146 GLY A CA  1 
ATOM   1078 C C   . GLY A 1 145 ? -26.60130 16.90449 -16.88020 1.000 24.55049 ? 146 GLY A C   1 
ATOM   1079 O O   . GLY A 1 145 ? -26.09835 15.98243 -17.53132 1.000 24.22306 ? 146 GLY A O   1 
ATOM   1080 N N   . SER A 1 146 ? -26.09251 18.13064 -16.89008 1.000 24.80640 ? 147 SER A N   1 
ATOM   1081 C CA  . SER A 1 146 ? -24.85502 18.41741 -17.60965 1.000 24.16169 ? 147 SER A CA  1 
ATOM   1082 C C   . SER A 1 146 ? -23.60062 18.01917 -16.83922 1.000 22.66557 ? 147 SER A C   1 
ATOM   1083 O O   . SER A 1 146 ? -22.50781 18.09837 -17.40743 1.000 20.80958 ? 147 SER A O   1 
ATOM   1084 C CB  . SER A 1 146 ? -24.77832 19.90755 -17.93993 1.000 24.54047 ? 147 SER A CB  1 
ATOM   1085 O OG  . SER A 1 146 ? -24.83094 20.68573 -16.74932 1.000 23.27193 ? 147 SER A OG  1 
ATOM   1086 N N   . ALA A 1 147 ? -23.71822 17.64922 -15.55751 1.000 21.08365 ? 148 ALA A N   1 
ATOM   1087 C CA  . ALA A 1 147 ? -22.56426 17.17026 -14.78892 1.000 20.11069 ? 148 ALA A CA  1 
ATOM   1088 C C   . ALA A 1 147 ? -21.73919 16.16010 -15.59317 1.000 19.32132 ? 148 ALA A C   1 
ATOM   1089 O O   . ALA A 1 147 ? -22.28487 15.28744 -16.26686 1.000 20.52149 ? 148 ALA A O   1 
ATOM   1090 C CB  . ALA A 1 147 ? -23.04740 16.53231 -13.48074 1.000 27.37496 ? 148 ALA A CB  1 
ATOM   1091 N N   . GLY A 1 148 ? -20.41237 16.30270 -15.54042 1.000 19.28396 ? 149 GLY A N   1 
ATOM   1092 C CA  . GLY A 1 148 ? -19.52984 15.47155 -16.33050 1.000 21.01127 ? 149 GLY A CA  1 
ATOM   1093 C C   . GLY A 1 148 ? -19.21481 16.00858 -17.70794 1.000 20.92564 ? 149 GLY A C   1 
ATOM   1094 O O   . GLY A 1 148 ? -18.37709 15.42225 -18.40441 1.000 20.25911 ? 149 GLY A O   1 
ATOM   1095 N N   . SER A 1 149 ? -19.86826 17.08756 -18.13279 1.000 20.79035 ? 150 SER A N   1 
ATOM   1096 C CA  . SER A 1 149 ? -19.42365 17.78657 -19.33490 1.000 20.42142 ? 150 SER A CA  1 
ATOM   1097 C C   . SER A 1 149 ? -18.00340 18.28235 -19.12193 1.000 20.55000 ? 150 SER A C   1 
ATOM   1098 O O   . SER A 1 149 ? -17.60661 18.60909 -18.00095 1.000 19.75485 ? 150 SER A O   1 
ATOM   1099 C CB  . SER A 1 149 ? -20.35413 18.95580 -19.65028 1.000 19.77361 ? 150 SER A CB  1 
ATOM   1100 O OG  . SER A 1 149 ? -21.64383 18.47836 -20.00820 1.000 25.38791 ? 150 SER A OG  1 
ATOM   1101 N N   . VAL A 1 150 ? -17.21232 18.32121 -20.19943 1.000 21.83436 ? 151 VAL A N   1 
ATOM   1102 C CA  . VAL A 1 150 ? -15.78950 18.58656 -20.01464 1.000 19.27308 ? 151 VAL A CA  1 
ATOM   1103 C C   . VAL A 1 150 ? -15.37587 19.85803 -20.74079 1.000 20.66425 ? 151 VAL A C   1 
ATOM   1104 O O   . VAL A 1 150 ? -15.96312 20.26055 -21.75132 1.000 19.45128 ? 151 VAL A O   1 
ATOM   1105 C CB  . VAL A 1 150 ? -14.90283 17.39098 -20.44364 1.000 22.08829 ? 151 VAL A CB  1 
ATOM   1106 C CG1 . VAL A 1 150 ? -15.38454 16.11497 -19.73583 1.000 21.62832 ? 151 VAL A CG1 1 
ATOM   1107 C CG2 . VAL A 1 150 ? -14.89691 17.19614 -21.92561 1.000 22.22284 ? 151 VAL A CG2 1 
ATOM   1108 N N   . GLY A 1 151 ? -14.34198 20.48895 -20.19588 1.000 18.16364 ? 152 GLY A N   1 
ATOM   1109 C CA  . GLY A 1 151 ? -13.72714 21.64614 -20.81260 1.000 19.09361 ? 152 GLY A CA  1 
ATOM   1110 C C   . GLY A 1 151 ? -12.29180 21.31097 -21.16087 1.000 18.23122 ? 152 GLY A C   1 
ATOM   1111 O O   . GLY A 1 151 ? -11.64036 20.51972 -20.47182 1.000 19.88757 ? 152 GLY A O   1 
ATOM   1112 N N   . TYR A 1 152 ? -11.79663 21.92213 -22.23455 1.000 18.18443 ? 153 TYR A N   1 
ATOM   1113 C CA  . TYR A 1 152 ? -10.51343 21.51077 -22.78298 1.000 19.54409 ? 153 TYR A CA  1 
ATOM   1114 C C   . TYR A 1 152 ? -9.96110  22.59408 -23.69967 1.000 21.61263 ? 153 TYR A C   1 
ATOM   1115 O O   . TYR A 1 152 ? -10.69111 23.45566 -24.18787 1.000 20.45464 ? 153 TYR A O   1 
ATOM   1116 C CB  . TYR A 1 152 ? -10.65961 20.19844 -23.54870 1.000 19.86250 ? 153 TYR A CB  1 
ATOM   1117 C CG  . TYR A 1 152 ? -11.70559 20.31287 -24.61894 1.000 20.95663 ? 153 TYR A CG  1 
ATOM   1118 C CD1 . TYR A 1 152 ? -13.05356 20.13937 -24.31489 1.000 22.23143 ? 153 TYR A CD1 1 
ATOM   1119 C CD2 . TYR A 1 152 ? -11.36186 20.62993 -25.92256 1.000 20.94071 ? 153 TYR A CD2 1 
ATOM   1120 C CE1 . TYR A 1 152 ? -14.02905 20.26817 -25.28996 1.000 24.70739 ? 153 TYR A CE1 1 
ATOM   1121 C CE2 . TYR A 1 152 ? -12.34846 20.76588 -26.91007 1.000 21.20390 ? 153 TYR A CE2 1 
ATOM   1122 C CZ  . TYR A 1 152 ? -13.66375 20.57824 -26.57569 1.000 23.44612 ? 153 TYR A CZ  1 
ATOM   1123 O OH  . TYR A 1 152 ? -14.64732 20.69792 -27.53321 1.000 34.68369 ? 153 TYR A OH  1 
ATOM   1124 N N   . THR A 1 153 ? -8.65225  22.53835 -23.91085 1.000 22.53948 ? 154 THR A N   1 
ATOM   1125 C CA  . THR A 1 153 ? -7.97235  23.29668 -24.94472 1.000 23.09910 ? 154 THR A CA  1 
ATOM   1126 C C   . THR A 1 153 ? -7.29198  22.30123 -25.87335 1.000 23.65015 ? 154 THR A C   1 
ATOM   1127 O O   . THR A 1 153 ? -7.23509  21.10195 -25.58975 1.000 20.40710 ? 154 THR A O   1 
ATOM   1128 C CB  . THR A 1 153 ? -6.96084  24.28631 -24.33847 1.000 23.42624 ? 154 THR A CB  1 
ATOM   1129 O OG1 . THR A 1 153 ? -6.02266  23.58695 -23.51616 1.000 23.11675 ? 154 THR A OG1 1 
ATOM   1130 C CG2 . THR A 1 153 ? -7.67894  25.33269 -23.46802 1.000 24.51511 ? 154 THR A CG2 1 
ATOM   1131 N N   . LYS A 1 154 ? -6.78415  22.78699 -27.00341 1.000 21.85422 ? 155 LYS A N   1 
ATOM   1132 C CA  . LYS A 1 154 ? -6.08455  21.90794 -27.93110 1.000 24.08982 ? 155 LYS A CA  1 
ATOM   1133 C C   . LYS A 1 154 ? -4.87773  22.63839 -28.49915 1.000 31.59395 ? 155 LYS A C   1 
ATOM   1134 O O   . LYS A 1 154 ? -5.00242  23.78779 -28.93297 1.000 31.20992 ? 155 LYS A O   1 
ATOM   1135 C CB  . LYS A 1 154 ? -7.00594  21.42677 -29.06675 1.000 27.55162 ? 155 LYS A CB  1 
ATOM   1136 C CG  . LYS A 1 154 ? -6.29873  20.43472 -30.00037 1.000 31.56041 ? 155 LYS A CG  1 
ATOM   1137 C CD  . LYS A 1 154 ? -7.24502  19.64196 -30.90454 1.000 35.05525 ? 155 LYS A CD  1 
ATOM   1138 C CE  . LYS A 1 154 ? -6.53631  18.35419 -31.35012 1.000 40.22984 ? 155 LYS A CE  1 
ATOM   1139 N NZ  . LYS A 1 154 ? -6.97964  17.81576 -32.68558 1.000 45.44878 ? 155 LYS A NZ  1 
ATOM   1140 N N   . GLU A 1 155 ? -3.71394  21.98161 -28.47623 1.000 28.88401 ? 156 GLU A N   1 
ATOM   1141 C CA  . GLU A 1 155 ? -2.48640  22.51458 -29.06773 1.000 33.17876 ? 156 GLU A CA  1 
ATOM   1142 C C   . GLU A 1 155 ? -1.83583  21.42880 -29.90783 1.000 34.81957 ? 156 GLU A C   1 
ATOM   1143 O O   . GLU A 1 155 ? -1.43395  20.38381 -29.37751 1.000 27.09295 ? 156 GLU A O   1 
ATOM   1144 C CB  . GLU A 1 155 ? -1.50544  23.00573 -28.00391 1.000 39.36246 ? 156 GLU A CB  1 
ATOM   1145 C CG  . GLU A 1 155 ? -0.19451  23.50303 -28.62367 1.000 49.03060 ? 156 GLU A CG  1 
ATOM   1146 C CD  . GLU A 1 155 ? 0.58062   24.43642 -27.70751 1.000 57.26343 ? 156 GLU A CD  1 
ATOM   1147 O OE1 . GLU A 1 155 ? 0.64957   24.14964 -26.49090 1.000 62.97158 ? 156 GLU A OE1 1 
ATOM   1148 O OE2 . GLU A 1 155 ? 1.11155   25.45989 -28.20283 1.000 55.25338 ? 156 GLU A OE2 1 
ATOM   1149 N N   . GLY A 1 156 ? -1.73411  21.67362 -31.20914 1.000 28.28365 ? 157 GLY A N   1 
ATOM   1150 C CA  . GLY A 1 156 ? -1.30556  20.60710 -32.08872 1.000 34.86124 ? 157 GLY A CA  1 
ATOM   1151 C C   . GLY A 1 156 ? -2.31376  19.48586 -32.01810 1.000 31.93356 ? 157 GLY A C   1 
ATOM   1152 O O   . GLY A 1 156 ? -3.52572  19.71129 -32.03603 1.000 33.32932 ? 157 GLY A O   1 
ATOM   1153 N N   . SER A 1 157 ? -1.82481  18.26081 -31.89763 1.000 29.22996 ? 158 SER A N   1 
ATOM   1154 C CA  . SER A 1 157 ? -2.71444  17.11028 -31.81797 1.000 30.96079 ? 158 SER A CA  1 
ATOM   1155 C C   . SER A 1 157 ? -3.18373  16.81306 -30.39544 1.000 33.24434 ? 158 SER A C   1 
ATOM   1156 O O   . SER A 1 157 ? -3.96395  15.87092 -30.19909 1.000 32.29107 ? 158 SER A O   1 
ATOM   1157 C CB  . SER A 1 157 ? -2.01677  15.87661 -32.38861 1.000 35.76093 ? 158 SER A CB  1 
ATOM   1158 O OG  . SER A 1 157 ? -0.90193  15.53176 -31.57788 1.000 34.49956 ? 158 SER A OG  1 
ATOM   1159 N N   . VAL A 1 158 ? -2.75185  17.58932 -29.40505 1.000 25.30817 ? 159 VAL A N   1 
ATOM   1160 C CA  . VAL A 1 158 ? -2.91702  17.22147 -28.00600 1.000 22.92005 ? 159 VAL A CA  1 
ATOM   1161 C C   . VAL A 1 158 ? -4.06231  18.01706 -27.39158 1.000 22.44385 ? 159 VAL A C   1 
ATOM   1162 O O   . VAL A 1 158 ? -4.04266  19.25102 -27.37000 1.000 22.86994 ? 159 VAL A O   1 
ATOM   1163 C CB  . VAL A 1 158 ? -1.61295  17.42427 -27.22450 1.000 25.57218 ? 159 VAL A CB  1 
ATOM   1164 C CG1 . VAL A 1 158 ? -1.77278  16.95396 -25.79752 1.000 23.22627 ? 159 VAL A CG1 1 
ATOM   1165 C CG2 . VAL A 1 158 ? -0.47358  16.65542 -27.91173 1.000 26.38723 ? 159 VAL A CG2 1 
ATOM   1166 N N   . ILE A 1 159 ? -5.06368  17.31514 -26.88813 1.000 22.33621 ? 160 ILE A N   1 
ATOM   1167 C CA  . ILE A 1 159 ? -6.11889  17.94405 -26.10298 1.000 20.82150 ? 160 ILE A CA  1 
ATOM   1168 C C   . ILE A 1 159 ? -5.66709  18.03679 -24.65498 1.000 22.20137 ? 160 ILE A C   1 
ATOM   1169 O O   . ILE A 1 159 ? -5.28584  17.02611 -24.05456 1.000 20.05433 ? 160 ILE A O   1 
ATOM   1170 C CB  . ILE A 1 159 ? -7.41791  17.14442 -26.20848 1.000 19.30969 ? 160 ILE A CB  1 
ATOM   1171 C CG1 . ILE A 1 159 ? -7.85209  17.09402 -27.67015 1.000 26.90450 ? 160 ILE A CG1 1 
ATOM   1172 C CG2 . ILE A 1 159 ? -8.48563  17.72579 -25.25024 1.000 19.07371 ? 160 ILE A CG2 1 
ATOM   1173 C CD1 . ILE A 1 159 ? -9.23515  16.59098 -27.85760 1.000 32.50773 ? 160 ILE A CD1 1 
ATOM   1174 N N   . ASN A 1 160 ? -5.76129  19.22702 -24.06871 1.000 17.97420 ? 161 ASN A N   1 
ATOM   1175 C CA  . ASN A 1 160 ? -5.59340  19.38005 -22.63248 1.000 19.11026 ? 161 ASN A CA  1 
ATOM   1176 C C   . ASN A 1 160 ? -6.97471  19.43867 -21.99460 1.000 21.79373 ? 161 ASN A C   1 
ATOM   1177 O O   . ASN A 1 160 ? -7.70596  20.41247 -22.18811 1.000 22.71666 ? 161 ASN A O   1 
ATOM   1178 C CB  . ASN A 1 160 ? -4.80957  20.63451 -22.25800 1.000 21.42415 ? 161 ASN A CB  1 
ATOM   1179 C CG  . ASN A 1 160 ? -4.64391  20.75401 -20.74521 1.000 26.93436 ? 161 ASN A CG  1 
ATOM   1180 O OD1 . ASN A 1 160 ? -3.98925  19.90602 -20.13068 1.000 34.16087 ? 161 ASN A OD1 1 
ATOM   1181 N ND2 . ASN A 1 160 ? -5.28383  21.74871 -20.12938 1.000 26.35982 ? 161 ASN A ND2 1 
ATOM   1182 N N   . PHE A 1 161 ? -7.32925  18.40137 -21.24649 1.000 18.92694 ? 162 PHE A N   1 
ATOM   1183 C CA  . PHE A 1 161 ? -8.56524  18.39740 -20.46706 1.000 20.82691 ? 162 PHE A CA  1 
ATOM   1184 C C   . PHE A 1 161 ? -8.33638  19.16458 -19.17139 1.000 20.92333 ? 162 PHE A C   1 
ATOM   1185 O O   . PHE A 1 161 ? -7.44190  18.81494 -18.39611 1.000 23.67564 ? 162 PHE A O   1 
ATOM   1186 C CB  . PHE A 1 161 ? -9.00327  16.95781 -20.19046 1.000 19.51944 ? 162 PHE A CB  1 
ATOM   1187 C CG  . PHE A 1 161 ? -9.47463  16.22400 -21.41874 1.000 19.62553 ? 162 PHE A CG  1 
ATOM   1188 C CD1 . PHE A 1 161 ? -10.69539 16.53924 -21.99583 1.000 20.37260 ? 162 PHE A CD1 1 
ATOM   1189 C CD2 . PHE A 1 161 ? -8.69491  15.23104 -22.00771 1.000 18.21308 ? 162 PHE A CD2 1 
ATOM   1190 C CE1 . PHE A 1 161 ? -11.15039 15.85772 -23.13206 1.000 16.76686 ? 162 PHE A CE1 1 
ATOM   1191 C CE2 . PHE A 1 161 ? -9.13711  14.54840 -23.14072 1.000 20.00424 ? 162 PHE A CE2 1 
ATOM   1192 C CZ  . PHE A 1 161 ? -10.36127 14.86475 -23.70735 1.000 17.85442 ? 162 PHE A CZ  1 
ATOM   1193 N N   . CYS A 1 162 ? -9.13043  20.22153 -18.93479 1.000 18.35973 ? 163 CYS A N   1 
ATOM   1194 C CA  . CYS A 1 162 ? -8.92626  21.07748 -17.77427 1.000 22.35007 ? 163 CYS A CA  1 
ATOM   1195 C C   . CYS A 1 162 ? -10.12355 21.20158 -16.84026 1.000 20.96093 ? 163 CYS A C   1 
ATOM   1196 O O   . CYS A 1 162 ? -9.96596  21.77680 -15.75878 1.000 21.02097 ? 163 CYS A O   1 
ATOM   1197 C CB  . CYS A 1 162 ? -8.51338  22.49209 -18.20964 1.000 22.19274 ? 163 CYS A CB  1 
ATOM   1198 S SG  . CYS A 1 162 ? -9.65704  23.30769 -19.38666 1.000 24.13228 ? 163 CYS A SG  1 
ATOM   1199 N N   . TYR A 1 163 ? -11.29898 20.69246 -17.20756 1.000 19.16127 ? 164 TYR A N   1 
ATOM   1200 C CA  . TYR A 1 163 ? -12.51994 20.95690 -16.44606 1.000 20.01291 ? 164 TYR A CA  1 
ATOM   1201 C C   . TYR A 1 163 ? -13.49578 19.81729 -16.65613 1.000 20.37937 ? 164 TYR A C   1 
ATOM   1202 O O   . TYR A 1 163 ? -13.67565 19.36651 -17.78730 1.000 20.91806 ? 164 TYR A O   1 
ATOM   1203 C CB  . TYR A 1 163 ? -13.16692 22.27090 -16.89481 1.000 19.51230 ? 164 TYR A CB  1 
ATOM   1204 C CG  . TYR A 1 163 ? -14.46003 22.69077 -16.19934 1.000 19.86549 ? 164 TYR A CG  1 
ATOM   1205 C CD1 . TYR A 1 163 ? -14.43148 23.48696 -15.07169 1.000 19.46837 ? 164 TYR A CD1 1 
ATOM   1206 C CD2 . TYR A 1 163 ? -15.70993 22.33399 -16.72150 1.000 17.80723 ? 164 TYR A CD2 1 
ATOM   1207 C CE1 . TYR A 1 163 ? -15.62724 23.91975 -14.45817 1.000 21.31784 ? 164 TYR A CE1 1 
ATOM   1208 C CE2 . TYR A 1 163 ? -16.90355 22.75673 -16.12485 1.000 18.62938 ? 164 TYR A CE2 1 
ATOM   1209 C CZ  . TYR A 1 163 ? -16.85264 23.54340 -14.99233 1.000 21.59112 ? 164 TYR A CZ  1 
ATOM   1210 O OH  . TYR A 1 163 ? -18.02553 23.96432 -14.38470 1.000 23.40503 ? 164 TYR A OH  1 
ATOM   1211 N N   . MET A 1 164 ? -14.12564 19.35725 -15.57673 1.000 20.15197 ? 165 MET A N   1 
ATOM   1212 C CA  . MET A 1 164 ? -15.27347 18.45837 -15.68371 1.000 22.42343 ? 165 MET A CA  1 
ATOM   1213 C C   . MET A 1 164 ? -16.38041 19.04518 -14.82245 1.000 21.24329 ? 165 MET A C   1 
ATOM   1214 O O   . MET A 1 164 ? -16.17621 19.27431 -13.62997 1.000 21.32315 ? 165 MET A O   1 
ATOM   1215 C CB  . MET A 1 164 ? -14.93179 17.03542 -15.23874 1.000 23.43491 ? 165 MET A CB  1 
ATOM   1216 C CG  . MET A 1 164 ? -16.14786 16.16062 -15.05909 1.000 21.73532 ? 165 MET A CG  1 
ATOM   1217 S SD  . MET A 1 164 ? -15.81095 14.38705 -15.06775 1.000 23.88187 ? 165 MET A SD  1 
ATOM   1218 C CE  . MET A 1 164 ? -15.50823 14.04022 -16.78898 1.000 21.48162 ? 165 MET A CE  1 
ATOM   1219 N N   . HIS A 1 165 ? -17.53167 19.31439 -15.42886 1.000 20.83487 ? 166 HIS A N   1 
ATOM   1220 C CA  . HIS A 1 165 ? -18.56332 20.07731 -14.74069 1.000 23.46002 ? 166 HIS A CA  1 
ATOM   1221 C C   . HIS A 1 165 ? -19.12698 19.31475 -13.54624 1.000 20.97564 ? 166 HIS A C   1 
ATOM   1222 O O   . HIS A 1 165 ? -19.42017 18.11705 -13.63580 1.000 20.95136 ? 166 HIS A O   1 
ATOM   1223 C CB  . HIS A 1 165 ? -19.69961 20.42950 -15.69384 1.000 19.67418 ? 166 HIS A CB  1 
ATOM   1224 C CG  . HIS A 1 165 ? -20.75133 21.26506 -15.04704 1.000 23.59648 ? 166 HIS A CG  1 
ATOM   1225 N ND1 . HIS A 1 165 ? -20.47522 22.50487 -14.50825 1.000 22.79832 ? 166 HIS A ND1 1 
ATOM   1226 C CD2 . HIS A 1 165 ? -22.06621 21.03342 -14.81511 1.000 22.41409 ? 166 HIS A CD2 1 
ATOM   1227 C CE1 . HIS A 1 165 ? -21.58086 23.01209 -13.99212 1.000 24.65843 ? 166 HIS A CE1 1 
ATOM   1228 N NE2 . HIS A 1 165 ? -22.56092 22.14117 -14.16446 1.000 23.34232 ? 166 HIS A NE2 1 
ATOM   1229 N N   . GLN A 1 166 ? -19.31976 20.03462 -12.43601 1.000 18.95135 ? 167 GLN A N   1 
ATOM   1230 C CA  . GLN A 1 166 ? -19.75815 19.43593 -11.17626 1.000 24.61124 ? 167 GLN A CA  1 
ATOM   1231 C C   . GLN A 1 166 ? -21.10694 19.95492 -10.70172 1.000 27.68411 ? 167 GLN A C   1 
ATOM   1232 O O   . GLN A 1 166 ? -22.00660 19.14709 -10.41511 1.000 25.05455 ? 167 GLN A O   1 
ATOM   1233 C CB  . GLN A 1 166 ? -18.71357 19.67361 -10.07115 1.000 26.35084 ? 167 GLN A CB  1 
ATOM   1234 C CG  . GLN A 1 166 ? -17.44361 18.82880 -10.19528 1.000 24.72216 ? 167 GLN A CG  1 
ATOM   1235 C CD  . GLN A 1 166 ? -17.58426 17.45252 -9.56847  1.000 30.14331 ? 167 GLN A CD  1 
ATOM   1236 O OE1 . GLN A 1 166 ? -18.62995 17.11876 -9.00605  1.000 27.95794 ? 167 GLN A OE1 1 
ATOM   1237 N NE2 . GLN A 1 166 ? -16.53672 16.64007 -9.68143  1.000 24.19798 ? 167 GLN A NE2 1 
ATOM   1238 N N   . MET A 1 167 ? -21.29423 21.27439 -10.61401 1.000 23.55623 ? 168 MET A N   1 
ATOM   1239 C CA  . MET A 1 167 ? -22.47831 21.75314 -9.90845  1.000 28.00398 ? 168 MET A CA  1 
ATOM   1240 C C   . MET A 1 167 ? -22.75951 23.21634 -10.22076 1.000 29.59958 ? 168 MET A C   1 
ATOM   1241 O O   . MET A 1 167 ? -21.87878 23.97108 -10.64152 1.000 27.80373 ? 168 MET A O   1 
ATOM   1242 C CB  . MET A 1 167 ? -22.30698 21.58054 -8.39874  1.000 27.97126 ? 168 MET A CB  1 
ATOM   1243 C CG  . MET A 1 167 ? -21.19000 22.44792 -7.84811  1.000 35.70821 ? 168 MET A CG  1 
ATOM   1244 S SD  . MET A 1 167 ? -20.67272 21.91879 -6.20743  1.000 41.48268 ? 168 MET A SD  1 
ATOM   1245 C CE  . MET A 1 167 ? -22.28421 21.45807 -5.52527  1.000 34.76771 ? 168 MET A CE  1 
ATOM   1246 N N   . GLU A 1 168 ? -24.01366 23.59952 -9.99366  1.000 30.79220 ? 169 GLU A N   1 
ATOM   1247 C CA  . GLU A 1 168 ? -24.44054 24.98738 -10.00747 1.000 32.48333 ? 169 GLU A CA  1 
ATOM   1248 C C   . GLU A 1 168 ? -24.30962 25.55083 -8.60134  1.000 36.98820 ? 169 GLU A C   1 
ATOM   1249 O O   . GLU A 1 168 ? -24.64245 24.87909 -7.62301  1.000 37.64046 ? 169 GLU A O   1 
ATOM   1250 C CB  . GLU A 1 168 ? -25.89121 25.10159 -10.47996 1.000 35.62144 ? 169 GLU A CB  1 
ATOM   1251 C CG  . GLU A 1 168 ? -26.40253 26.53009 -10.63505 1.000 39.75765 ? 169 GLU A CG  1 
ATOM   1252 C CD  . GLU A 1 168 ? -27.81037 26.57326 -11.20394 1.000 47.42024 ? 169 GLU A CD  1 
ATOM   1253 O OE1 . GLU A 1 168 ? -28.70586 27.11436 -10.52226 1.000 57.19188 ? 169 GLU A OE1 1 
ATOM   1254 O OE2 . GLU A 1 168 ? -28.02653 26.04621 -12.31903 1.000 42.04979 ? 169 GLU A OE2 1 
ATOM   1255 N N   . LEU A 1 169 ? -23.81204 26.77693 -8.50314  1.000 37.36522 ? 170 LEU A N   1 
ATOM   1256 C CA  . LEU A 1 169 ? -23.66681 27.44483 -7.22093  1.000 40.44117 ? 170 LEU A CA  1 
ATOM   1257 C C   . LEU A 1 169 ? -24.83568 28.39906 -7.00009  1.000 48.69770 ? 170 LEU A C   1 
ATOM   1258 O O   . LEU A 1 169 ? -25.65340 28.64906 -7.89386  1.000 49.24479 ? 170 LEU A O   1 
ATOM   1259 C CB  . LEU A 1 169 ? -22.32610 28.17717 -7.14379  1.000 41.92233 ? 170 LEU A CB  1 
ATOM   1260 C CG  . LEU A 1 169 ? -21.11489 27.23602 -7.23701  1.000 39.71149 ? 170 LEU A CG  1 
ATOM   1261 C CD1 . LEU A 1 169 ? -19.81348 28.02673 -7.42209  1.000 42.74922 ? 170 LEU A CD1 1 
ATOM   1262 C CD2 . LEU A 1 169 ? -21.02152 26.31243 -6.03356  1.000 37.36995 ? 170 LEU A CD2 1 
ATOM   1263 N N   . ALA A 1 170 ? -24.90166 28.93634 -5.78019  1.000 51.04155 ? 171 ALA A N   1 
ATOM   1264 C CA  . ALA A 1 170 ? -26.09091 29.66279 -5.34167  1.000 57.41356 ? 171 ALA A CA  1 
ATOM   1265 C C   . ALA A 1 170 ? -26.35137 30.92614 -6.16418  1.000 57.15689 ? 171 ALA A C   1 
ATOM   1266 O O   . ALA A 1 170 ? -27.50228 31.36611 -6.25769  1.000 58.90866 ? 171 ALA A O   1 
ATOM   1267 C CB  . ALA A 1 170 ? -25.96807 30.00303 -3.85408  1.000 51.15790 ? 171 ALA A CB  1 
ATOM   1268 N N   . ASN A 1 171 ? -25.32249 31.51971 -6.77470  1.000 57.40540 ? 172 ASN A N   1 
ATOM   1269 C CA  . ASN A 1 171 ? -25.50422 32.75783 -7.52356  1.000 59.94982 ? 172 ASN A CA  1 
ATOM   1270 C C   . ASN A 1 171 ? -25.77530 32.52998 -9.01222  1.000 57.20379 ? 172 ASN A C   1 
ATOM   1271 O O   . ASN A 1 171 ? -25.59796 33.46301 -9.80604  1.000 59.89673 ? 172 ASN A O   1 
ATOM   1272 C CB  . ASN A 1 171 ? -24.29083 33.67790 -7.34408  1.000 59.38996 ? 172 ASN A CB  1 
ATOM   1273 C CG  . ASN A 1 171 ? -23.00556 33.07291 -7.87910  1.000 60.45430 ? 172 ASN A CG  1 
ATOM   1274 O OD1 . ASN A 1 171 ? -22.88121 31.85631 -8.00277  1.000 59.63430 ? 172 ASN A OD1 1 
ATOM   1275 N ND2 . ASN A 1 171 ? -22.02663 33.92486 -8.16855  1.000 62.02430 ? 172 ASN A ND2 1 
ATOM   1276 N N   . GLY A 1 172 ? -26.22995 31.33368 -9.40188  1.000 52.88916 ? 173 GLY A N   1 
ATOM   1277 C CA  . GLY A 1 172 ? -26.49501 31.04087 -10.80272 1.000 54.41513 ? 173 GLY A CA  1 
ATOM   1278 C C   . GLY A 1 172 ? -25.26232 30.71437 -11.61708 1.000 53.49318 ? 173 GLY A C   1 
ATOM   1279 O O   . GLY A 1 172 ? -25.29613 30.77083 -12.85144 1.000 49.76744 ? 173 GLY A O   1 
ATOM   1280 N N   . THR A 1 173 ? -24.17979 30.35316 -10.95210 1.000 46.77391 ? 174 THR A N   1 
ATOM   1281 C CA  . THR A 1 173 ? -22.84724 30.21130 -11.50454 1.000 43.42095 ? 174 THR A CA  1 
ATOM   1282 C C   . THR A 1 173 ? -22.40358 28.75637 -11.32398 1.000 34.36042 ? 174 THR A C   1 
ATOM   1283 O O   . THR A 1 173 ? -23.06384 27.98510 -10.62915 1.000 34.25086 ? 174 THR A O   1 
ATOM   1284 C CB  . THR A 1 173 ? -21.95567 31.24988 -10.81003 1.000 47.33177 ? 174 THR A CB  1 
ATOM   1285 O OG1 . THR A 1 173 ? -22.14562 32.54757 -11.40116 1.000 53.94234 ? 174 THR A OG1 1 
ATOM   1286 C CG2 . THR A 1 173 ? -20.55983 30.87764 -10.75245 1.000 38.07195 ? 174 THR A CG2 1 
ATOM   1287 N N   . HIS A 1 174 ? -21.32355 28.34502 -11.99569 1.000 27.22391 ? 175 HIS A N   1 
ATOM   1288 C CA  . HIS A 1 174 ? -20.98066 26.92980 -12.09843 1.000 26.64842 ? 175 HIS A CA  1 
ATOM   1289 C C   . HIS A 1 174 ? -19.54092 26.66112 -11.69168 1.000 26.23919 ? 175 HIS A C   1 
ATOM   1290 O O   . HIS A 1 174 ? -18.65944 27.49970 -11.87734 1.000 31.80314 ? 175 HIS A O   1 
ATOM   1291 C CB  . HIS A 1 174 ? -21.20653 26.43554 -13.52093 1.000 27.66708 ? 175 HIS A CB  1 
ATOM   1292 C CG  . HIS A 1 174 ? -22.57515 26.73298 -14.03027 1.000 28.43238 ? 175 HIS A CG  1 
ATOM   1293 N ND1 . HIS A 1 174 ? -22.81992 27.68124 -14.99832 1.000 32.60646 ? 175 HIS A ND1 1 
ATOM   1294 C CD2 . HIS A 1 174 ? -23.78238 26.22920 -13.68039 1.000 28.85981 ? 175 HIS A CD2 1 
ATOM   1295 C CE1 . HIS A 1 174 ? -24.11924 27.73903 -15.23448 1.000 31.42247 ? 175 HIS A CE1 1 
ATOM   1296 N NE2 . HIS A 1 174 ? -24.72506 26.87135 -14.44466 1.000 32.02189 ? 175 HIS A NE2 1 
ATOM   1297 N N   . THR A 1 175 ? -19.29413 25.47509 -11.13559 1.000 28.86760 ? 176 THR A N   1 
ATOM   1298 C CA  . THR A 1 175 ? -17.91073 25.06204 -10.95238 1.000 25.97142 ? 176 THR A CA  1 
ATOM   1299 C C   . THR A 1 175 ? -17.76048 23.57032 -11.21592 1.000 24.93071 ? 176 THR A C   1 
ATOM   1300 O O   . THR A 1 175 ? -18.73187 22.83661 -11.43882 1.000 25.95968 ? 176 THR A O   1 
ATOM   1301 C CB  . THR A 1 175 ? -17.35493 25.43140 -9.56772  1.000 29.97407 ? 176 THR A CB  1 
ATOM   1302 O OG1 . THR A 1 175 ? -15.90998 25.40551 -9.62330  1.000 28.93824 ? 176 THR A OG1 1 
ATOM   1303 C CG2 . THR A 1 175 ? -17.84661 24.45830 -8.50848  1.000 29.86200 ? 176 THR A CG2 1 
ATOM   1304 N N   . GLY A 1 176 ? -16.50275 23.15233 -11.25714 1.000 22.08205 ? 177 GLY A N   1 
ATOM   1305 C CA  . GLY A 1 176 ? -16.14652 21.81371 -11.67109 1.000 23.62052 ? 177 GLY A CA  1 
ATOM   1306 C C   . GLY A 1 176 ? -14.75864 21.50158 -11.16792 1.000 22.37608 ? 177 GLY A C   1 
ATOM   1307 O O   . GLY A 1 176 ? -14.14812 22.28765 -10.43698 1.000 23.12566 ? 177 GLY A O   1 
ATOM   1308 N N   . SER A 1 177 ? -14.27669 20.32714 -11.57596 1.000 22.48502 ? 178 SER A N   1 
ATOM   1309 C CA  . SER A 1 177 ? -13.00576 19.76671 -11.14799 1.000 26.10955 ? 178 SER A CA  1 
ATOM   1310 C C   . SER A 1 177 ? -11.96950 19.87012 -12.25393 1.000 24.31788 ? 178 SER A C   1 
ATOM   1311 O O   . SER A 1 177 ? -12.29844 19.82123 -13.44100 1.000 22.75755 ? 178 SER A O   1 
ATOM   1312 C CB  . SER A 1 177 ? -13.14166 18.28094 -10.77962 1.000 24.15545 ? 178 SER A CB  1 
ATOM   1313 O OG  . SER A 1 177 ? -14.33234 18.03100 -10.06967 1.000 31.64278 ? 178 SER A OG  1 
ATOM   1314 N N   . ALA A 1 178 ? -10.71485 19.98898 -11.84534 1.000 24.08629 ? 179 ALA A N   1 
ATOM   1315 C CA  . ALA A 1 178 ? -9.59999  19.58546 -12.68579 1.000 22.81678 ? 179 ALA A CA  1 
ATOM   1316 C C   . ALA A 1 178 ? -9.47831  18.06198 -12.64117 1.000 24.38306 ? 179 ALA A C   1 
ATOM   1317 O O   . ALA A 1 178 ? -10.00189 17.40508 -11.73863 1.000 25.24308 ? 179 ALA A O   1 
ATOM   1318 C CB  . ALA A 1 178 ? -8.30027  20.23640 -12.20702 1.000 22.56218 ? 179 ALA A CB  1 
ATOM   1319 N N   . PHE A 1 179 ? -8.79126  17.49324 -13.62508 1.000 24.84939 ? 180 PHE A N   1 
ATOM   1320 C CA  . PHE A 1 179 ? -8.73637  16.03611 -13.66942 1.000 24.00188 ? 180 PHE A CA  1 
ATOM   1321 C C   . PHE A 1 179 ? -7.71931  15.45346 -12.69894 1.000 26.35928 ? 180 PHE A C   1 
ATOM   1322 O O   . PHE A 1 179 ? -7.58075  14.23162 -12.64401 1.000 27.37705 ? 180 PHE A O   1 
ATOM   1323 C CB  . PHE A 1 179 ? -8.47482  15.54778 -15.09729 1.000 21.04846 ? 180 PHE A CB  1 
ATOM   1324 C CG  . PHE A 1 179 ? -9.70514  15.60100 -15.97013 1.000 22.19891 ? 180 PHE A CG  1 
ATOM   1325 C CD1 . PHE A 1 179 ? -10.13490 16.80690 -16.50852 1.000 22.34062 ? 180 PHE A CD1 1 
ATOM   1326 C CD2 . PHE A 1 179 ? -10.44924 14.45677 -16.21997 1.000 25.85864 ? 180 PHE A CD2 1 
ATOM   1327 C CE1 . PHE A 1 179 ? -11.28254 16.87240 -17.29801 1.000 21.42649 ? 180 PHE A CE1 1 
ATOM   1328 C CE2 . PHE A 1 179 ? -11.60625 14.50873 -17.00776 1.000 23.69437 ? 180 PHE A CE2 1 
ATOM   1329 C CZ  . PHE A 1 179 ? -12.01438 15.71886 -17.55306 1.000 22.44662 ? 180 PHE A CZ  1 
ATOM   1330 N N   . ASP A 1 180 ? -7.02069  16.28295 -11.92340 1.000 24.92951 ? 181 ASP A N   1 
ATOM   1331 C CA  . ASP A 1 180 ? -6.35621  15.74232 -10.74534 1.000 30.84781 ? 181 ASP A CA  1 
ATOM   1332 C C   . ASP A 1 180 ? -7.33493  15.52147 -9.60148  1.000 30.69772 ? 181 ASP A C   1 
ATOM   1333 O O   . ASP A 1 180 ? -6.94562  14.96941 -8.57120  1.000 32.30922 ? 181 ASP A O   1 
ATOM   1334 C CB  . ASP A 1 180 ? -5.17818  16.63462 -10.31110 1.000 26.93784 ? 181 ASP A CB  1 
ATOM   1335 C CG  . ASP A 1 180 ? -5.58766  18.02378 -9.85270  1.000 30.89065 ? 181 ASP A CG  1 
ATOM   1336 O OD1 . ASP A 1 180 ? -6.78856  18.34049 -9.74748  1.000 31.75996 ? 181 ASP A OD1 1 
ATOM   1337 O OD2 . ASP A 1 180 ? -4.67093  18.82370 -9.56439  1.000 35.73804 ? 181 ASP A OD2 1 
ATOM   1338 N N   . GLY A 1 181 ? -8.60158  15.90797 -9.77664  1.000 28.94179 ? 182 GLY A N   1 
ATOM   1339 C CA  . GLY A 1 181 ? -9.63912  15.66113 -8.80442  1.000 27.85003 ? 182 GLY A CA  1 
ATOM   1340 C C   . GLY A 1 181 ? -9.98372  16.84482 -7.93083  1.000 27.22809 ? 182 GLY A C   1 
ATOM   1341 O O   . GLY A 1 181 ? -10.98811 16.78963 -7.21070  1.000 26.62217 ? 182 GLY A O   1 
ATOM   1342 N N   . THR A 1 182 ? -9.20249  17.91790 -7.98425  1.000 23.76523 ? 183 THR A N   1 
ATOM   1343 C CA  . THR A 1 182 ? -9.46718  19.07878 -7.15191  1.000 26.85635 ? 183 THR A CA  1 
ATOM   1344 C C   . THR A 1 182 ? -10.57094 19.91860 -7.76878  1.000 30.74844 ? 183 THR A C   1 
ATOM   1345 O O   . THR A 1 182 ? -10.60918 20.11436 -8.98841  1.000 27.29618 ? 183 THR A O   1 
ATOM   1346 C CB  . THR A 1 182 ? -8.20628  19.92162 -6.99852  1.000 31.04199 ? 183 THR A CB  1 
ATOM   1347 O OG1 . THR A 1 182 ? -7.91500  20.56235 -8.25073  1.000 37.13486 ? 183 THR A OG1 1 
ATOM   1348 C CG2 . THR A 1 182 ? -7.03922  19.03750 -6.58236  1.000 25.63577 ? 183 THR A CG2 1 
ATOM   1349 N N   . MET A 1 183 ? -11.47514 20.40076 -6.92119  1.000 24.38950 ? 184 MET A N   1 
ATOM   1350 C CA  . MET A 1 183 ? -12.52263 21.30737 -7.35346  1.000 26.34629 ? 184 MET A CA  1 
ATOM   1351 C C   . MET A 1 183 ? -11.94751 22.70733 -7.50630  1.000 27.41420 ? 184 MET A C   1 
ATOM   1352 O O   . MET A 1 183 ? -11.27444 23.21595 -6.59854  1.000 27.29010 ? 184 MET A O   1 
ATOM   1353 C CB  . MET A 1 183 ? -13.67375 21.30871 -6.34558  1.000 27.84137 ? 184 MET A CB  1 
ATOM   1354 C CG  . MET A 1 183 ? -14.87488 22.10745 -6.80385  1.000 28.34825 ? 184 MET A CG  1 
ATOM   1355 S SD  . MET A 1 183 ? -15.88119 21.11031 -7.92104  1.000 32.82321 ? 184 MET A SD  1 
ATOM   1356 C CE  . MET A 1 183 ? -16.59348 19.93249 -6.76353  1.000 30.23526 ? 184 MET A CE  1 
ATOM   1357 N N   . TYR A 1 184 ? -12.18225 23.32632 -8.66514  1.000 24.46244 ? 185 TYR A N   1 
ATOM   1358 C CA  . TYR A 1 184 ? -11.84411 24.73523 -8.80828  1.000 24.16503 ? 185 TYR A CA  1 
ATOM   1359 C C   . TYR A 1 184 ? -12.53406 25.54504 -7.71817  1.000 27.42754 ? 185 TYR A C   1 
ATOM   1360 O O   . TYR A 1 184 ? -13.74091 25.41231 -7.50442  1.000 25.33294 ? 185 TYR A O   1 
ATOM   1361 C CB  . TYR A 1 184 ? -12.25503 25.25046 -10.19202 1.000 25.43229 ? 185 TYR A CB  1 
ATOM   1362 C CG  . TYR A 1 184 ? -11.30594 24.79777 -11.28026 1.000 23.19729 ? 185 TYR A CG  1 
ATOM   1363 C CD1 . TYR A 1 184 ? -10.10131 25.44907 -11.48614 1.000 26.70673 ? 185 TYR A CD1 1 
ATOM   1364 C CD2 . TYR A 1 184 ? -11.60451 23.69613 -12.06627 1.000 24.04434 ? 185 TYR A CD2 1 
ATOM   1365 C CE1 . TYR A 1 184 ? -9.22411  25.03494 -12.46068 1.000 24.47652 ? 185 TYR A CE1 1 
ATOM   1366 C CE2 . TYR A 1 184 ? -10.73780 23.26281 -13.05636 1.000 20.69229 ? 185 TYR A CE2 1 
ATOM   1367 C CZ  . TYR A 1 184 ? -9.55362  23.94039 -13.25317 1.000 24.82052 ? 185 TYR A CZ  1 
ATOM   1368 O OH  . TYR A 1 184 ? -8.67810  23.52186 -14.22948 1.000 24.11593 ? 185 TYR A OH  1 
ATOM   1369 N N   . GLY A 1 185 ? -11.75930 26.37950 -7.02293  1.000 28.97639 ? 186 GLY A N   1 
ATOM   1370 C CA  . GLY A 1 185 ? -12.31738 27.21459 -5.97845  1.000 29.40589 ? 186 GLY A CA  1 
ATOM   1371 C C   . GLY A 1 185 ? -12.62599 26.50790 -4.67852  1.000 32.67513 ? 186 GLY A C   1 
ATOM   1372 O O   . GLY A 1 185 ? -13.16989 27.14616 -3.76346  1.000 30.98439 ? 186 GLY A O   1 
ATOM   1373 N N   . ALA A 1 186 ? -12.32302 25.21248 -4.58078  1.000 29.22622 ? 187 ALA A N   1 
ATOM   1374 C CA  . ALA A 1 186 ? -12.43762 24.42285 -3.36078  1.000 31.83424 ? 187 ALA A CA  1 
ATOM   1375 C C   . ALA A 1 186 ? -13.87990 24.19301 -2.92989  1.000 32.68500 ? 187 ALA A C   1 
ATOM   1376 O O   . ALA A 1 186 ? -14.12585 23.82088 -1.78276  1.000 34.44773 ? 187 ALA A O   1 
ATOM   1377 C CB  . ALA A 1 186 ? -11.63850 25.05878 -2.20968  1.000 31.27610 ? 187 ALA A CB  1 
ATOM   1378 N N   . PHE A 1 187 ? -14.85134 24.37493 -3.82030  1.000 32.63844 ? 188 PHE A N   1 
ATOM   1379 C CA  . PHE A 1 187 ? -16.23510 24.13674 -3.43754  1.000 33.90045 ? 188 PHE A CA  1 
ATOM   1380 C C   . PHE A 1 187 ? -16.47413 22.65784 -3.12547  1.000 33.26523 ? 188 PHE A C   1 
ATOM   1381 O O   . PHE A 1 187 ? -15.77962 21.77055 -3.61928  1.000 33.46570 ? 188 PHE A O   1 
ATOM   1382 C CB  . PHE A 1 187 ? -17.17389 24.62049 -4.54068  1.000 36.80269 ? 188 PHE A CB  1 
ATOM   1383 C CG  . PHE A 1 187 ? -17.03711 26.08748 -4.83004  1.000 34.74613 ? 188 PHE A CG  1 
ATOM   1384 C CD1 . PHE A 1 187 ? -17.55049 27.02869 -3.94823  1.000 34.02762 ? 188 PHE A CD1 1 
ATOM   1385 C CD2 . PHE A 1 187 ? -16.34976 26.52515 -5.95444  1.000 29.83331 ? 188 PHE A CD2 1 
ATOM   1386 C CE1 . PHE A 1 187 ? -17.40212 28.38468 -4.19492  1.000 38.42093 ? 188 PHE A CE1 1 
ATOM   1387 C CE2 . PHE A 1 187 ? -16.19947 27.87662 -6.20815  1.000 33.80838 ? 188 PHE A CE2 1 
ATOM   1388 C CZ  . PHE A 1 187 ? -16.72613 28.81097 -5.33162  1.000 34.45637 ? 188 PHE A CZ  1 
ATOM   1389 N N   . MET A 1 188 ? -17.45585 22.39968 -2.26985  1.000 38.43752 ? 189 MET A N   1 
ATOM   1390 C CA  . MET A 1 188 ? -17.77719 21.04170 -1.85812  1.000 39.22623 ? 189 MET A CA  1 
ATOM   1391 C C   . MET A 1 188 ? -18.88135 20.48244 -2.74480  1.000 35.56519 ? 189 MET A C   1 
ATOM   1392 O O   . MET A 1 188 ? -19.83931 21.18540 -3.07409  1.000 34.67638 ? 189 MET A O   1 
ATOM   1393 C CB  . MET A 1 188 ? -18.23031 21.00695 -0.39503  1.000 36.93831 ? 189 MET A CB  1 
ATOM   1394 C CG  . MET A 1 188 ? -17.22656 21.54700 0.61715   1.000 42.02788 ? 189 MET A CG  1 
ATOM   1395 S SD  . MET A 1 188 ? -17.96274 21.74457 2.26371   1.000 48.48780 ? 189 MET A SD  1 
ATOM   1396 C CE  . MET A 1 188 ? -18.68089 23.38366 2.10633   1.000 43.02331 ? 189 MET A CE  1 
ATOM   1397 N N   . ASP A 1 189 ? -18.75575 19.20872 -3.11518  1.000 31.45173 ? 190 ASP A N   1 
ATOM   1398 C CA  . ASP A 1 189 ? -19.78660 18.55233 -3.92126  1.000 32.88785 ? 190 ASP A CA  1 
ATOM   1399 C C   . ASP A 1 189 ? -20.87518 17.96321 -3.01590  1.000 33.15450 ? 190 ASP A C   1 
ATOM   1400 O O   . ASP A 1 189 ? -21.03809 16.74410 -2.87377  1.000 32.67186 ? 190 ASP A O   1 
ATOM   1401 C CB  . ASP A 1 189 ? -19.17248 17.49433 -4.83381  1.000 28.65386 ? 190 ASP A CB  1 
ATOM   1402 C CG  . ASP A 1 189 ? -18.13379 16.63414 -4.14340  1.000 30.83009 ? 190 ASP A CG  1 
ATOM   1403 O OD1 . ASP A 1 189 ? -17.68415 16.97672 -3.02697  1.000 32.27784 ? 190 ASP A OD1 1 
ATOM   1404 O OD2 . ASP A 1 189 ? -17.73476 15.61385 -4.74892  1.000 31.26904 ? 190 ASP A OD2 1 
ATOM   1405 N N   . LYS A 1 190 ? -21.64043 18.87589 -2.41663  1.000 31.08735 ? 191 LYS A N   1 
ATOM   1406 C CA  . LYS A 1 190 ? -22.77860 18.55735 -1.56263  1.000 39.87806 ? 191 LYS A CA  1 
ATOM   1407 C C   . LYS A 1 190 ? -23.82480 19.64620 -1.70840  1.000 42.97518 ? 191 LYS A C   1 
ATOM   1408 O O   . LYS A 1 190 ? -23.54340 20.74048 -2.20296  1.000 40.22476 ? 191 LYS A O   1 
ATOM   1409 C CB  . LYS A 1 190 ? -22.41333 18.46525 -0.07373  1.000 41.57082 ? 191 LYS A CB  1 
ATOM   1410 C CG  . LYS A 1 190 ? -21.10544 17.82895 0.23477   1.000 46.08241 ? 191 LYS A CG  1 
ATOM   1411 C CD  . LYS A 1 190 ? -20.44591 18.49679 1.43196   1.000 48.29543 ? 191 LYS A CD  1 
ATOM   1412 C CE  . LYS A 1 190 ? -21.37575 18.55233 2.62865   1.000 50.69019 ? 191 LYS A CE  1 
ATOM   1413 N NZ  . LYS A 1 190 ? -20.59819 18.83387 3.86976   1.000 50.94958 ? 191 LYS A NZ  1 
ATOM   1414 N N   . GLN A 1 191 ? -25.03578 19.34228 -1.23827  1.000 42.35260 ? 192 GLN A N   1 
ATOM   1415 C CA  . GLN A 1 191 ? -26.09643 20.34161 -1.12756  1.000 45.82414 ? 192 GLN A CA  1 
ATOM   1416 C C   . GLN A 1 191 ? -25.92045 21.05383 0.20560   1.000 48.30923 ? 192 GLN A C   1 
ATOM   1417 O O   . GLN A 1 191 ? -26.48112 20.66015 1.23056   1.000 48.37878 ? 192 GLN A O   1 
ATOM   1418 C CB  . GLN A 1 191 ? -27.47058 19.69653 -1.23803  1.000 45.57475 ? 192 GLN A CB  1 
ATOM   1419 C CG  . GLN A 1 191 ? -28.59876 20.69905 -1.28665  1.000 49.99971 ? 192 GLN A CG  1 
ATOM   1420 C CD  . GLN A 1 191 ? -29.91190 20.05297 -1.65452  1.000 57.76498 ? 192 GLN A CD  1 
ATOM   1421 O OE1 . GLN A 1 191 ? -30.31883 20.05768 -2.81844  1.000 60.73755 ? 192 GLN A OE1 1 
ATOM   1422 N NE2 . GLN A 1 191 ? -30.57864 19.47395 -0.66463  1.000 54.13524 ? 192 GLN A NE2 1 
ATOM   1423 N N   . VAL A 1 192 ? -25.12435 22.11961 0.18704   1.000 45.90557 ? 193 VAL A N   1 
ATOM   1424 C CA  . VAL A 1 192 ? -24.74641 22.84379 1.39274   1.000 48.70797 ? 193 VAL A CA  1 
ATOM   1425 C C   . VAL A 1 192 ? -24.55406 24.30020 1.00362   1.000 48.05902 ? 193 VAL A C   1 
ATOM   1426 O O   . VAL A 1 192 ? -24.14165 24.60453 -0.11545  1.000 43.66685 ? 193 VAL A O   1 
ATOM   1427 C CB  . VAL A 1 192 ? -23.46829 22.23522 2.02828   1.000 49.95143 ? 193 VAL A CB  1 
ATOM   1428 C CG1 . VAL A 1 192 ? -22.66733 23.27495 2.79969   1.000 53.05815 ? 193 VAL A CG1 1 
ATOM   1429 C CG2 . VAL A 1 192 ? -23.82746 21.06863 2.93973   1.000 50.91954 ? 193 VAL A CG2 1 
ATOM   1430 N N   . HIS A 1 193 ? -24.88759 25.20626 1.91819   1.000 52.24010 ? 194 HIS A N   1 
ATOM   1431 C CA  . HIS A 1 193 ? -24.65263 26.62081 1.66450   1.000 54.21114 ? 194 HIS A CA  1 
ATOM   1432 C C   . HIS A 1 193 ? -23.15611 26.89229 1.54703   1.000 52.54375 ? 194 HIS A C   1 
ATOM   1433 O O   . HIS A 1 193 ? -22.38801 26.62551 2.47975   1.000 52.65320 ? 194 HIS A O   1 
ATOM   1434 C CB  . HIS A 1 193 ? -25.26043 27.47264 2.77834   1.000 58.29877 ? 194 HIS A CB  1 
ATOM   1435 C CG  . HIS A 1 193 ? -24.83572 28.90828 2.72932   1.000 61.05570 ? 194 HIS A CG  1 
ATOM   1436 N ND1 . HIS A 1 193 ? -23.76305 29.39263 3.44958   1.000 63.84697 ? 194 HIS A ND1 1 
ATOM   1437 C CD2 . HIS A 1 193 ? -25.32503 29.96079 2.02989   1.000 59.27693 ? 194 HIS A CD2 1 
ATOM   1438 C CE1 . HIS A 1 193 ? -23.61669 30.68328 3.20445   1.000 60.63188 ? 194 HIS A CE1 1 
ATOM   1439 N NE2 . HIS A 1 193 ? -24.55076 31.05229 2.34530   1.000 62.68528 ? 194 HIS A NE2 1 
ATOM   1440 N N   . GLN A 1 194 ? -22.73748 27.40594 0.39142   1.000 52.60570 ? 195 GLN A N   1 
ATOM   1441 C CA  . GLN A 1 194 ? -21.35818 27.82616 0.18786   1.000 52.79796 ? 195 GLN A CA  1 
ATOM   1442 C C   . GLN A 1 194 ? -21.33562 29.19128 -0.47907  1.000 52.90052 ? 195 GLN A C   1 
ATOM   1443 O O   . GLN A 1 194 ? -22.17555 29.49400 -1.33313  1.000 51.96506 ? 195 GLN A O   1 
ATOM   1444 C CB  . GLN A 1 194 ? -20.56684 26.83621 -0.66406  1.000 46.61990 ? 195 GLN A CB  1 
ATOM   1445 C CG  . GLN A 1 194 ? -21.36693 25.68570 -1.20725  1.000 47.83170 ? 195 GLN A CG  1 
ATOM   1446 C CD  . GLN A 1 194 ? -20.47430 24.58316 -1.71454  1.000 39.01611 ? 195 GLN A CD  1 
ATOM   1447 O OE1 . GLN A 1 194 ? -19.26439 24.59307 -1.47972  1.000 39.17257 ? 195 GLN A OE1 1 
ATOM   1448 N NE2 . GLN A 1 194 ? -21.05914 23.62579 -2.41188  1.000 39.82424 ? 195 GLN A NE2 1 
ATOM   1449 N N   . VAL A 1 195 ? -20.36807 30.00458 -0.08592  1.000 50.38903 ? 196 VAL A N   1 
ATOM   1450 C CA  . VAL A 1 195 ? -20.20498 31.34984 -0.62097  1.000 56.63318 ? 196 VAL A CA  1 
ATOM   1451 C C   . VAL A 1 195 ? -19.06690 31.33809 -1.63169  1.000 50.19083 ? 196 VAL A C   1 
ATOM   1452 O O   . VAL A 1 195 ? -18.03233 30.68869 -1.42097  1.000 49.58404 ? 196 VAL A O   1 
ATOM   1453 C CB  . VAL A 1 195 ? -19.95079 32.37461 0.50622   1.000 57.89220 ? 196 VAL A CB  1 
ATOM   1454 C CG1 . VAL A 1 195 ? -18.58599 32.14065 1.17393   1.000 53.73614 ? 196 VAL A CG1 1 
ATOM   1455 C CG2 . VAL A 1 195 ? -20.07175 33.80668 -0.03400  1.000 54.43207 ? 196 VAL A CG2 1 
ATOM   1456 N N   . GLN A 1 196 ? -19.27108 32.01933 -2.75201  1.000 50.95853 ? 197 GLN A N   1 
ATOM   1457 C CA  . GLN A 1 196 ? -18.20048 32.25694 -3.70637  1.000 50.67338 ? 197 GLN A CA  1 
ATOM   1458 C C   . GLN A 1 196 ? -17.65990 33.66081 -3.49718  1.000 44.64358 ? 197 GLN A C   1 
ATOM   1459 O O   . GLN A 1 196 ? -18.41795 34.58473 -3.18768  1.000 44.17628 ? 197 GLN A O   1 
ATOM   1460 C CB  . GLN A 1 196 ? -18.68277 32.07975 -5.14319  1.000 46.58287 ? 197 GLN A CB  1 
ATOM   1461 C CG  . GLN A 1 196 ? -19.73122 31.00588 -5.28085  1.000 50.90856 ? 197 GLN A CG  1 
ATOM   1462 C CD  . GLN A 1 196 ? -21.10664 31.60110 -5.29073  1.000 56.93918 ? 197 GLN A CD  1 
ATOM   1463 O OE1 . GLN A 1 196 ? -21.27493 32.74790 -5.69659  1.000 61.54961 ? 197 GLN A OE1 1 
ATOM   1464 N NE2 . GLN A 1 196 ? -22.09988 30.84461 -4.82664  1.000 55.42982 ? 197 GLN A NE2 1 
ATOM   1465 N N   . LEU A 1 197 ? -16.34196 33.80006 -3.62939  1.000 39.39815 ? 198 LEU A N   1 
ATOM   1466 C CA  . LEU A 1 197 ? -15.69426 35.09190 -3.50771  1.000 37.99231 ? 198 LEU A CA  1 
ATOM   1467 C C   . LEU A 1 197 ? -16.15897 36.02111 -4.62269  1.000 36.91184 ? 198 LEU A C   1 
ATOM   1468 O O   . LEU A 1 197 ? -16.80240 35.60939 -5.59003  1.000 31.71762 ? 198 LEU A O   1 
ATOM   1469 C CB  . LEU A 1 197 ? -14.17986 34.93777 -3.56790  1.000 38.50768 ? 198 LEU A CB  1 
ATOM   1470 C CG  . LEU A 1 197 ? -13.61615 33.88514 -2.62654  1.000 42.12491 ? 198 LEU A CG  1 
ATOM   1471 C CD1 . LEU A 1 197 ? -12.13591 33.68264 -2.91281  1.000 41.88534 ? 198 LEU A CD1 1 
ATOM   1472 C CD2 . LEU A 1 197 ? -13.83819 34.31814 -1.18864  1.000 42.76701 ? 198 LEU A CD2 1 
ATOM   1473 N N   . THR A 1 198 ? -15.82306 37.29975 -4.47574  1.000 34.09651 ? 199 THR A N   1 
ATOM   1474 C CA  . THR A 1 198 ? -16.24425 38.28793 -5.46036  1.000 39.56987 ? 199 THR A CA  1 
ATOM   1475 C C   . THR A 1 198 ? -15.56443 38.02474 -6.79896  1.000 33.75975 ? 199 THR A C   1 
ATOM   1476 O O   . THR A 1 198 ? -14.38335 37.67258 -6.85586  1.000 35.87404 ? 199 THR A O   1 
ATOM   1477 C CB  . THR A 1 198 ? -15.92443 39.70953 -4.97115  1.000 41.81648 ? 199 THR A CB  1 
ATOM   1478 O OG1 . THR A 1 198 ? -16.28351 40.64930 -5.98747  1.000 43.48227 ? 199 THR A OG1 1 
ATOM   1479 C CG2 . THR A 1 198 ? -14.42881 39.87572 -4.65019  1.000 41.02371 ? 199 THR A CG2 1 
ATOM   1480 N N   . ASP A 1 199 ? -16.32681 38.16105 -7.87938  1.000 29.62444 ? 200 ASP A N   1 
ATOM   1481 C CA  . ASP A 1 199 ? -15.70578 38.13844 -9.19365  1.000 35.59630 ? 200 ASP A CA  1 
ATOM   1482 C C   . ASP A 1 199 ? -14.87964 39.41213 -9.39445  1.000 35.08784 ? 200 ASP A C   1 
ATOM   1483 O O   . ASP A 1 199 ? -15.00358 40.39296 -8.65106  1.000 31.94219 ? 200 ASP A O   1 
ATOM   1484 C CB  . ASP A 1 199 ? -16.76406 37.99579 -10.29007 1.000 32.64996 ? 200 ASP A CB  1 
ATOM   1485 C CG  . ASP A 1 199 ? -16.24053 37.25422 -11.53450 1.000 36.08878 ? 200 ASP A CG  1 
ATOM   1486 O OD1 . ASP A 1 199 ? -15.04254 36.90768 -11.57148 1.000 32.84562 ? 200 ASP A OD1 1 
ATOM   1487 O OD2 . ASP A 1 199 ? -17.04406 37.01208 -12.46692 1.000 36.75381 ? 200 ASP A OD2 1 
ATOM   1488 N N   . LYS A 1 200 ? -13.99166 39.36916 -10.38573 1.000 28.55973 ? 201 LYS A N   1 
ATOM   1489 C CA  . LYS A 1 200 ? -13.17123 40.51355 -10.75518 1.000 26.86606 ? 201 LYS A CA  1 
ATOM   1490 C C   . LYS A 1 200 ? -13.03699 40.53564 -12.26352 1.000 28.50489 ? 201 LYS A C   1 
ATOM   1491 O O   . LYS A 1 200 ? -13.16383 39.50166 -12.92200 1.000 26.23116 ? 201 LYS A O   1 
ATOM   1492 C CB  . LYS A 1 200 ? -11.76930 40.46301 -10.14421 1.000 27.80608 ? 201 LYS A CB  1 
ATOM   1493 C CG  . LYS A 1 200 ? -11.72170 40.33434 -8.63672  1.000 32.11997 ? 201 LYS A CG  1 
ATOM   1494 C CD  . LYS A 1 200 ? -10.28326 40.18308 -8.15307  1.000 33.31802 ? 201 LYS A CD  1 
ATOM   1495 C CE  . LYS A 1 200 ? -10.20122 40.27315 -6.61851  1.000 38.39759 ? 201 LYS A CE  1 
ATOM   1496 N NZ  . LYS A 1 200 ? -8.80310  40.10286 -6.12794  1.000 43.35972 ? 201 LYS A NZ  1 
ATOM   1497 N N   . TYR A 1 201 ? -12.78011 41.72595 -12.80718 1.000 26.53882 ? 202 TYR A N   1 
ATOM   1498 C CA  . TYR A 1 201 ? -12.40713 41.84013 -14.20999 1.000 26.43009 ? 202 TYR A CA  1 
ATOM   1499 C C   . TYR A 1 201 ? -11.00267 41.29983 -14.40693 1.000 24.47207 ? 202 TYR A C   1 
ATOM   1500 O O   . TYR A 1 201 ? -10.09821 41.59360 -13.61849 1.000 26.26274 ? 202 TYR A O   1 
ATOM   1501 C CB  . TYR A 1 201 ? -12.43734 43.29894 -14.67529 1.000 25.63358 ? 202 TYR A CB  1 
ATOM   1502 C CG  . TYR A 1 201 ? -13.79588 43.91541 -14.88502 1.000 29.66342 ? 202 TYR A CG  1 
ATOM   1503 C CD1 . TYR A 1 201 ? -14.58395 43.56334 -15.97232 1.000 31.97393 ? 202 TYR A CD1 1 
ATOM   1504 C CD2 . TYR A 1 201 ? -14.27031 44.90102 -14.02161 1.000 34.00033 ? 202 TYR A CD2 1 
ATOM   1505 C CE1 . TYR A 1 201 ? -15.82648 44.15227 -16.18093 1.000 37.58306 ? 202 TYR A CE1 1 
ATOM   1506 C CE2 . TYR A 1 201 ? -15.50830 45.49882 -14.22328 1.000 38.54347 ? 202 TYR A CE2 1 
ATOM   1507 C CZ  . TYR A 1 201 ? -16.27718 45.12258 -15.30534 1.000 40.21941 ? 202 TYR A CZ  1 
ATOM   1508 O OH  . TYR A 1 201 ? -17.50660 45.71143 -15.49698 1.000 46.69835 ? 202 TYR A OH  1 
ATOM   1509 N N   . CYS A 1 202 ? -10.81881 40.51599 -15.47036 1.000 23.11347 ? 203 CYS A N   1 
ATOM   1510 C CA  . CYS A 1 202 ? -9.50691  39.98441 -15.85238 1.000 23.30369 ? 203 CYS A CA  1 
ATOM   1511 C C   . CYS A 1 202 ? -8.75651  41.06162 -16.63010 1.000 24.16784 ? 203 CYS A C   1 
ATOM   1512 O O   . CYS A 1 202 ? -8.97721  41.24308 -17.83116 1.000 21.42031 ? 203 CYS A O   1 
ATOM   1513 C CB  . CYS A 1 202 ? -9.66989  38.71051 -16.67926 1.000 23.99327 ? 203 CYS A CB  1 
ATOM   1514 S SG  . CYS A 1 202 ? -10.51642 37.36132 -15.76978 1.000 28.59674 ? 203 CYS A SG  1 
ATOM   1515 N N   . SER A 1 203 ? -7.86965  41.78256 -15.93055 1.000 22.60098 ? 204 SER A N   1 
ATOM   1516 C CA  . SER A 1 203 ? -7.23006  42.97288 -16.49183 1.000 21.66622 ? 204 SER A CA  1 
ATOM   1517 C C   . SER A 1 203 ? -6.51476  42.68058 -17.80643 1.000 20.79840 ? 204 SER A C   1 
ATOM   1518 O O   . SER A 1 203 ? -6.60555  43.46824 -18.75478 1.000 19.66197 ? 204 SER A O   1 
ATOM   1519 C CB  . SER A 1 203 ? -6.24494  43.56123 -15.47498 1.000 23.81667 ? 204 SER A CB  1 
ATOM   1520 O OG  . SER A 1 203 ? -6.94018  43.90565 -14.28786 1.000 24.57545 ? 204 SER A OG  1 
ATOM   1521 N N   . VAL A 1 204 ? -5.79035  41.56137 -17.88648 1.000 19.57541 ? 205 VAL A N   1 
ATOM   1522 C CA  . VAL A 1 204 ? -5.00072  41.34162 -19.09521 1.000 21.00900 ? 205 VAL A CA  1 
ATOM   1523 C C   . VAL A 1 204 ? -5.90466  41.07002 -20.29959 1.000 21.20489 ? 205 VAL A C   1 
ATOM   1524 O O   . VAL A 1 204 ? -5.54800  41.40346 -21.43876 1.000 19.31157 ? 205 VAL A O   1 
ATOM   1525 C CB  . VAL A 1 204 ? -3.97035  40.22344 -18.86948 1.000 23.56020 ? 205 VAL A CB  1 
ATOM   1526 C CG1 . VAL A 1 204 ? -4.65493  38.86371 -18.73341 1.000 23.78249 ? 205 VAL A CG1 1 
ATOM   1527 C CG2 . VAL A 1 204 ? -2.95565  40.21623 -20.02083 1.000 22.48147 ? 205 VAL A CG2 1 
ATOM   1528 N N   . ASN A 1 205 ? -7.09314  40.49543 -20.07552 1.000 19.58588 ? 206 ASN A N   1 
ATOM   1529 C CA  . ASN A 1 205 ? -8.02544  40.27804 -21.18020 1.000 20.38769 ? 206 ASN A CA  1 
ATOM   1530 C C   . ASN A 1 205 ? -8.70142  41.57760 -21.59817 1.000 21.12496 ? 206 ASN A C   1 
ATOM   1531 O O   . ASN A 1 205 ? -8.94900  41.78258 -22.79289 1.000 17.63979 ? 206 ASN A O   1 
ATOM   1532 C CB  . ASN A 1 205 ? -9.08842  39.23744 -20.80103 1.000 19.18025 ? 206 ASN A CB  1 
ATOM   1533 C CG  . ASN A 1 205 ? -8.50926  37.84874 -20.56262 1.000 19.33099 ? 206 ASN A CG  1 
ATOM   1534 O OD1 . ASN A 1 205 ? -7.36465  37.56815 -20.90424 1.000 18.83488 ? 206 ASN A OD1 1 
ATOM   1535 N ND2 . ASN A 1 205 ? -9.31206  36.96490 -19.97273 1.000 19.80537 ? 206 ASN A ND2 1 
ATOM   1536 N N   . VAL A 1 206 ? -8.97863  42.47223 -20.64385 1.000 17.88286 ? 207 VAL A N   1 
ATOM   1537 C CA  . VAL A 1 206 ? -9.47846  43.79234 -21.00842 1.000 16.66447 ? 207 VAL A CA  1 
ATOM   1538 C C   . VAL A 1 206 ? -8.45057  44.52853 -21.86373 1.000 18.63539 ? 207 VAL A C   1 
ATOM   1539 O O   . VAL A 1 206 ? -8.80453  45.18598 -22.83775 1.000 17.10583 ? 207 VAL A O   1 
ATOM   1540 C CB  . VAL A 1 206 ? -9.85748  44.61678 -19.75802 1.000 19.57330 ? 207 VAL A CB  1 
ATOM   1541 C CG1 . VAL A 1 206 ? -10.48792 45.92127 -20.18827 1.000 19.91820 ? 207 VAL A CG1 1 
ATOM   1542 C CG2 . VAL A 1 206 ? -10.81123 43.85236 -18.85463 1.000 20.95003 ? 207 VAL A CG2 1 
ATOM   1543 N N   . VAL A 1 207 ? -7.17102  44.45185 -21.49387 1.000 18.36978 ? 208 VAL A N   1 
ATOM   1544 C CA  . VAL A 1 207 ? -6.12509  45.06411 -22.30742 1.000 16.89157 ? 208 VAL A CA  1 
ATOM   1545 C C   . VAL A 1 207 ? -6.14774  44.49103 -23.72274 1.000 18.47044 ? 208 VAL A C   1 
ATOM   1546 O O   . VAL A 1 207 ? -6.06371  45.22678 -24.71552 1.000 20.11376 ? 208 VAL A O   1 
ATOM   1547 C CB  . VAL A 1 207 ? -4.75635  44.87021 -21.63012 1.000 20.77768 ? 208 VAL A CB  1 
ATOM   1548 C CG1 . VAL A 1 207 ? -3.63225  45.19325 -22.59137 1.000 20.19908 ? 208 VAL A CG1 1 
ATOM   1549 C CG2 . VAL A 1 207 ? -4.66447  45.73995 -20.38202 1.000 21.16400 ? 208 VAL A CG2 1 
ATOM   1550 N N   . ALA A 1 208 ? -6.25525  43.16351 -23.83569 1.000 16.98658 ? 209 ALA A N   1 
ATOM   1551 C CA  . ALA A 1 208 ? -6.26546  42.51921 -25.14627 1.000 19.24031 ? 209 ALA A CA  1 
ATOM   1552 C C   . ALA A 1 208 ? -7.43789  43.00407 -25.97413 1.000 19.01544 ? 209 ALA A C   1 
ATOM   1553 O O   . ALA A 1 208 ? -7.31371  43.23878 -27.18430 1.000 18.26080 ? 209 ALA A O   1 
ATOM   1554 C CB  . ALA A 1 208 ? -6.33658  40.98869 -24.97866 1.000 21.06922 ? 209 ALA A CB  1 
ATOM   1555 N N   . TRP A 1 209 ? -8.59212  43.13901 -25.33535 1.000 18.71252 ? 210 TRP A N   1 
ATOM   1556 C CA  . TRP A 1 209 ? -9.79389  43.57083 -26.04032 1.000 19.18756 ? 210 TRP A CA  1 
ATOM   1557 C C   . TRP A 1 209 ? -9.66964  45.01105 -26.52264 1.000 21.71827 ? 210 TRP A C   1 
ATOM   1558 O O   . TRP A 1 209 ? -10.09288 45.33232 -27.64512 1.000 18.72027 ? 210 TRP A O   1 
ATOM   1559 C CB  . TRP A 1 209 ? -10.99220 43.39512 -25.10875 1.000 19.54501 ? 210 TRP A CB  1 
ATOM   1560 C CG  . TRP A 1 209 ? -12.31916 43.91113 -25.60855 1.000 19.88998 ? 210 TRP A CG  1 
ATOM   1561 C CD1 . TRP A 1 209 ? -13.12251 43.35528 -26.57738 1.000 25.85602 ? 210 TRP A CD1 1 
ATOM   1562 C CD2 . TRP A 1 209 ? -13.01793 45.04822 -25.11320 1.000 19.36395 ? 210 TRP A CD2 1 
ATOM   1563 N NE1 . TRP A 1 209 ? -14.27125 44.10987 -26.72154 1.000 25.69047 ? 210 TRP A NE1 1 
ATOM   1564 C CE2 . TRP A 1 209 ? -14.23018 45.14535 -25.82494 1.000 25.71631 ? 210 TRP A CE2 1 
ATOM   1565 C CE3 . TRP A 1 209 ? -12.73514 46.00101 -24.13040 1.000 22.39328 ? 210 TRP A CE3 1 
ATOM   1566 C CZ2 . TRP A 1 209 ? -15.15371 46.16610 -25.58753 1.000 26.43765 ? 210 TRP A CZ2 1 
ATOM   1567 C CZ3 . TRP A 1 209 ? -13.65934 47.00506 -23.89063 1.000 25.41269 ? 210 TRP A CZ3 1 
ATOM   1568 C CH2 . TRP A 1 209 ? -14.84960 47.08044 -24.62454 1.000 24.28008 ? 210 TRP A CH2 1 
ATOM   1569 N N   . LEU A 1 210 ? -9.08617  45.89679 -25.69618 1.000 20.32140 ? 211 LEU A N   1 
ATOM   1570 C CA  . LEU A 1 210 ? -8.84553  47.26793 -26.15374 1.000 20.41830 ? 211 LEU A CA  1 
ATOM   1571 C C   . LEU A 1 210 ? -7.86577  47.30061 -27.32473 1.000 19.38184 ? 211 LEU A C   1 
ATOM   1572 O O   . LEU A 1 210 ? -8.03373  48.09948 -28.25232 1.000 20.22124 ? 211 LEU A O   1 
ATOM   1573 C CB  . LEU A 1 210 ? -8.32374  48.13604 -24.99922 1.000 19.01868 ? 211 LEU A CB  1 
ATOM   1574 C CG  . LEU A 1 210 ? -9.32847  48.25665 -23.85187 1.000 18.48680 ? 211 LEU A CG  1 
ATOM   1575 C CD1 . LEU A 1 210 ? -8.71337  49.01072 -22.67894 1.000 20.15706 ? 211 LEU A CD1 1 
ATOM   1576 C CD2 . LEU A 1 210 ? -10.58723 48.93719 -24.35319 1.000 21.20505 ? 211 LEU A CD2 1 
ATOM   1577 N N   . TYR A 1 211 ? -6.84510  46.42861 -27.31255 1.000 20.36137 ? 212 TYR A N   1 
ATOM   1578 C CA  . TYR A 1 211 ? -5.96944  46.30020 -28.48759 1.000 20.53098 ? 212 TYR A CA  1 
ATOM   1579 C C   . TYR A 1 211 ? -6.74855  45.83530 -29.71962 1.000 20.44052 ? 212 TYR A C   1 
ATOM   1580 O O   . TYR A 1 211 ? -6.49583  46.30360 -30.83794 1.000 23.50200 ? 212 TYR A O   1 
ATOM   1581 C CB  . TYR A 1 211 ? -4.80981  45.33505 -28.19527 1.000 19.55002 ? 212 TYR A CB  1 
ATOM   1582 C CG  . TYR A 1 211 ? -3.62315  45.97692 -27.50397 1.000 21.77642 ? 212 TYR A CG  1 
ATOM   1583 C CD1 . TYR A 1 211 ? -3.00155  47.11248 -28.04536 1.000 21.69595 ? 212 TYR A CD1 1 
ATOM   1584 C CD2 . TYR A 1 211 ? -3.10496  45.44092 -26.33704 1.000 20.85933 ? 212 TYR A CD2 1 
ATOM   1585 C CE1 . TYR A 1 211 ? -1.91582  47.70405 -27.41615 1.000 19.02994 ? 212 TYR A CE1 1 
ATOM   1586 C CE2 . TYR A 1 211 ? -2.01183  46.02294 -25.69642 1.000 21.61348 ? 212 TYR A CE2 1 
ATOM   1587 C CZ  . TYR A 1 211 ? -1.42943  47.15920 -26.24239 1.000 23.37729 ? 212 TYR A CZ  1 
ATOM   1588 O OH  . TYR A 1 211 ? -0.35583  47.74246 -25.60215 1.000 23.53089 ? 212 TYR A OH  1 
ATOM   1589 N N   . ALA A 1 212 ? -7.70728  44.92428 -29.54361 1.000 22.44556 ? 213 ALA A N   1 
ATOM   1590 C CA  . ALA A 1 212 ? -8.52212  44.49919 -30.68414 1.000 23.15257 ? 213 ALA A CA  1 
ATOM   1591 C C   . ALA A 1 212 ? -9.32012  45.67046 -31.23370 1.000 26.00814 ? 213 ALA A C   1 
ATOM   1592 O O   . ALA A 1 212 ? -9.47851  45.81680 -32.45435 1.000 22.75061 ? 213 ALA A O   1 
ATOM   1593 C CB  . ALA A 1 212 ? -9.45651  43.35671 -30.28488 1.000 20.70818 ? 213 ALA A CB  1 
ATOM   1594 N N   . ALA A 1 213 ? -9.80780  46.53129 -30.33716 1.000 24.22745 ? 214 ALA A N   1 
ATOM   1595 C CA  . ALA A 1 213 ? -10.53047 47.72715 -30.74936 1.000 25.77005 ? 214 ALA A CA  1 
ATOM   1596 C C   . ALA A 1 213 ? -9.63606  48.64594 -31.57303 1.000 24.27196 ? 214 ALA A C   1 
ATOM   1597 O O   . ALA A 1 213 ? -10.02725 49.11752 -32.64854 1.000 26.37449 ? 214 ALA A O   1 
ATOM   1598 C CB  . ALA A 1 213 ? -11.07478 48.44321 -29.51021 1.000 20.23047 ? 214 ALA A CB  1 
ATOM   1599 N N   . ILE A 1 214 ? -8.41796  48.88673 -31.09298 1.000 22.12668 ? 215 ILE A N   1 
ATOM   1600 C CA  . ILE A 1 214 ? -7.47843  49.73127 -31.82626 1.000 23.31283 ? 215 ILE A CA  1 
ATOM   1601 C C   . ILE A 1 214 ? -7.20651  49.13784 -33.19855 1.000 24.21132 ? 215 ILE A C   1 
ATOM   1602 O O   . ILE A 1 214 ? -7.20535  49.84760 -34.21136 1.000 23.77761 ? 215 ILE A O   1 
ATOM   1603 C CB  . ILE A 1 214 ? -6.18036  49.90054 -31.01084 1.000 23.55215 ? 215 ILE A CB  1 
ATOM   1604 C CG1 . ILE A 1 214 ? -6.46291  50.69146 -29.71589 1.000 21.83424 ? 215 ILE A CG1 1 
ATOM   1605 C CG2 . ILE A 1 214 ? -5.06083  50.54356 -31.87355 1.000 22.88281 ? 215 ILE A CG2 1 
ATOM   1606 C CD1 . ILE A 1 214 ? -5.37655  50.53968 -28.63778 1.000 20.38226 ? 215 ILE A CD1 1 
ATOM   1607 N N   . LEU A 1 215 ? -6.99334  47.81747 -33.25259 1.000 22.10246 ? 216 LEU A N   1 
ATOM   1608 C CA  . LEU A 1 215 ? -6.70660  47.15333 -34.51694 1.000 25.16143 ? 216 LEU A CA  1 
ATOM   1609 C C   . LEU A 1 215 ? -7.86380  47.28206 -35.49558 1.000 29.47267 ? 216 LEU A C   1 
ATOM   1610 O O   . LEU A 1 215 ? -7.65369  47.20636 -36.71111 1.000 29.28220 ? 216 LEU A O   1 
ATOM   1611 C CB  . LEU A 1 215 ? -6.38135  45.67847 -34.26945 1.000 25.74723 ? 216 LEU A CB  1 
ATOM   1612 C CG  . LEU A 1 215 ? -5.00307  45.36936 -33.68793 1.000 24.41622 ? 216 LEU A CG  1 
ATOM   1613 C CD1 . LEU A 1 215 ? -4.90437  43.87456 -33.38392 1.000 28.01845 ? 216 LEU A CD1 1 
ATOM   1614 C CD2 . LEU A 1 215 ? -3.92408  45.76410 -34.68377 1.000 30.13305 ? 216 LEU A CD2 1 
ATOM   1615 N N   . ASN A 1 216 ? -9.08343  47.47264 -34.99569 1.000 27.55376 ? 217 ASN A N   1 
ATOM   1616 C CA  . ASN A 1 216 ? -10.26062 47.61435 -35.84182 1.000 28.04535 ? 217 ASN A CA  1 
ATOM   1617 C C   . ASN A 1 216 ? -10.65341 49.07504 -36.07303 1.000 29.99519 ? 217 ASN A C   1 
ATOM   1618 O O   . ASN A 1 216 ? -11.76032 49.33793 -36.55018 1.000 33.33710 ? 217 ASN A O   1 
ATOM   1619 C CB  . ASN A 1 216 ? -11.44044 46.84451 -35.23649 1.000 31.86738 ? 217 ASN A CB  1 
ATOM   1620 C CG  . ASN A 1 216 ? -11.34133 45.33551 -35.46847 1.000 36.65227 ? 217 ASN A CG  1 
ATOM   1621 O OD1 . ASN A 1 216 ? -11.04069 44.57565 -34.55407 1.000 39.60062 ? 217 ASN A OD1 1 
ATOM   1622 N ND2 . ASN A 1 216 ? -11.58833 44.90411 -36.69789 1.000 38.82756 ? 217 ASN A ND2 1 
ATOM   1623 N N   . GLY A 1 217 ? -9.77566  50.02551 -35.75823 1.000 30.56950 ? 218 GLY A N   1 
ATOM   1624 C CA  . GLY A 1 217 ? -10.05851 51.44051 -35.96529 1.000 33.98680 ? 218 GLY A CA  1 
ATOM   1625 C C   . GLY A 1 217 ? -10.89558 52.10837 -34.89330 1.000 33.28343 ? 218 GLY A C   1 
ATOM   1626 O O   . GLY A 1 217 ? -11.43948 53.19473 -35.13430 1.000 33.57796 ? 218 GLY A O   1 
ATOM   1627 N N   . CYS A 1 218 ? -11.03256 51.49619 -33.72836 1.000 26.87463 ? 219 CYS A N   1 
ATOM   1628 C CA  . CYS A 1 218 ? -11.79741 52.06278 -32.61267 1.000 28.84606 ? 219 CYS A CA  1 
ATOM   1629 C C   . CYS A 1 218 ? -10.79422 52.41901 -31.51758 1.000 28.50609 ? 219 CYS A C   1 
ATOM   1630 O O   . CYS A 1 218 ? -10.37416 51.55534 -30.73739 1.000 26.74585 ? 219 CYS A O   1 
ATOM   1631 C CB  . CYS A 1 218 ? -12.85512 51.07357 -32.12350 1.000 31.92917 ? 219 CYS A CB  1 
ATOM   1632 S SG  . CYS A 1 218 ? -13.79841 51.61845 -30.68168 1.000 34.13411 ? 219 CYS A SG  1 
ATOM   1633 N N   . ALA A 1 219 ? -10.38966 53.69448 -31.47843 1.000 27.65073 ? 220 ALA A N   1 
ATOM   1634 C CA  . ALA A 1 219 ? -9.32485  54.11093 -30.57457 1.000 27.20581 ? 220 ALA A CA  1 
ATOM   1635 C C   . ALA A 1 219 ? -9.62971  55.44601 -29.90002 1.000 28.08433 ? 220 ALA A C   1 
ATOM   1636 O O   . ALA A 1 219 ? -8.70925  56.09003 -29.38026 1.000 26.02383 ? 220 ALA A O   1 
ATOM   1637 C CB  . ALA A 1 219 ? -7.98275  54.19523 -31.32182 1.000 26.17964 ? 220 ALA A CB  1 
ATOM   1638 N N   . TRP A 1 220 ? -10.90308 55.85016 -29.85885 1.000 27.41980 ? 221 TRP A N   1 
ATOM   1639 C CA  . TRP A 1 220 ? -11.28038 57.12104 -29.24168 1.000 29.24556 ? 221 TRP A CA  1 
ATOM   1640 C C   . TRP A 1 220 ? -10.83373 57.22231 -27.78840 1.000 29.18881 ? 221 TRP A C   1 
ATOM   1641 O O   . TRP A 1 220 ? -10.63010 58.33297 -27.29154 1.000 30.28930 ? 221 TRP A O   1 
ATOM   1642 C CB  . TRP A 1 220 ? -12.79782 57.33415 -29.34051 1.000 27.90871 ? 221 TRP A CB  1 
ATOM   1643 C CG  . TRP A 1 220 ? -13.65424 56.29770 -28.61692 1.000 25.92664 ? 221 TRP A CG  1 
ATOM   1644 C CD1 . TRP A 1 220 ? -14.28243 55.22455 -29.18081 1.000 26.80933 ? 221 TRP A CD1 1 
ATOM   1645 C CD2 . TRP A 1 220 ? -13.98105 56.25656 -27.21328 1.000 27.49870 ? 221 TRP A CD2 1 
ATOM   1646 N NE1 . TRP A 1 220 ? -14.97092 54.51229 -28.22151 1.000 26.91372 ? 221 TRP A NE1 1 
ATOM   1647 C CE2 . TRP A 1 220 ? -14.80176 55.12370 -27.00758 1.000 25.88567 ? 221 TRP A CE2 1 
ATOM   1648 C CE3 . TRP A 1 220 ? -13.65029 57.05945 -26.11135 1.000 28.92811 ? 221 TRP A CE3 1 
ATOM   1649 C CZ2 . TRP A 1 220 ? -15.29857 54.77548 -25.74632 1.000 27.86848 ? 221 TRP A CZ2 1 
ATOM   1650 C CZ3 . TRP A 1 220 ? -14.14681 56.71537 -24.85774 1.000 28.11430 ? 221 TRP A CZ3 1 
ATOM   1651 C CH2 . TRP A 1 220 ? -14.96126 55.58242 -24.68711 1.000 29.05255 ? 221 TRP A CH2 1 
ATOM   1652 N N   . PHE A 1 221 ? -10.66951 56.09050 -27.09404 1.000 24.52378 ? 222 PHE A N   1 
ATOM   1653 C CA  . PHE A 1 221 ? -10.30797 56.05383 -25.67998 1.000 25.06546 ? 222 PHE A CA  1 
ATOM   1654 C C   . PHE A 1 221 ? -8.80473  56.14180 -25.42087 1.000 26.20430 ? 222 PHE A C   1 
ATOM   1655 O O   . PHE A 1 221 ? -8.39546  56.13919 -24.25415 1.000 25.70531 ? 222 PHE A O   1 
ATOM   1656 C CB  . PHE A 1 221 ? -10.83016 54.75524 -25.05029 1.000 25.13262 ? 222 PHE A CB  1 
ATOM   1657 C CG  . PHE A 1 221 ? -10.41614 53.52742 -25.81497 1.000 23.91291 ? 222 PHE A CG  1 
ATOM   1658 C CD1 . PHE A 1 221 ? -9.16221  52.95512 -25.61568 1.000 22.31040 ? 222 PHE A CD1 1 
ATOM   1659 C CD2 . PHE A 1 221 ? -11.25704 52.98371 -26.77546 1.000 25.31711 ? 222 PHE A CD2 1 
ATOM   1660 C CE1 . PHE A 1 221 ? -8.76382  51.83854 -26.34536 1.000 22.13987 ? 222 PHE A CE1 1 
ATOM   1661 C CE2 . PHE A 1 221 ? -10.87020 51.86722 -27.52454 1.000 20.69358 ? 222 PHE A CE2 1 
ATOM   1662 C CZ  . PHE A 1 221 ? -9.62710  51.29718 -27.31262 1.000 23.97242 ? 222 PHE A CZ  1 
ATOM   1663 N N   . VAL A 1 222 ? -7.96696  56.16890 -26.45069 1.000 24.89743 ? 223 VAL A N   1 
ATOM   1664 C CA  . VAL A 1 222 ? -6.52169  56.17342 -26.24632 1.000 24.83938 ? 223 VAL A CA  1 
ATOM   1665 C C   . VAL A 1 222 ? -6.06511  57.61440 -26.02849 1.000 24.36327 ? 223 VAL A C   1 
ATOM   1666 O O   . VAL A 1 222 ? -6.34543  58.49327 -26.84419 1.000 23.62455 ? 223 VAL A O   1 
ATOM   1667 C CB  . VAL A 1 222 ? -5.78600  55.52975 -27.43015 1.000 28.74164 ? 223 VAL A CB  1 
ATOM   1668 C CG1 . VAL A 1 222 ? -4.26319  55.62038 -27.22492 1.000 27.90664 ? 223 VAL A CG1 1 
ATOM   1669 C CG2 . VAL A 1 222 ? -6.20842  54.07486 -27.58367 1.000 24.28027 ? 223 VAL A CG2 1 
ATOM   1670 N N   . LYS A 1 223 ? -5.38063  57.85381 -24.91970 1.000 24.49794 ? 224 LYS A N   1 
ATOM   1671 C CA  . LYS A 1 223 ? -4.80086  59.13938 -24.57110 1.000 28.63051 ? 224 LYS A CA  1 
ATOM   1672 C C   . LYS A 1 223 ? -3.29513  58.98584 -24.45822 1.000 26.33570 ? 224 LYS A C   1 
ATOM   1673 O O   . LYS A 1 223 ? -2.78219  57.86907 -24.29904 1.000 23.20845 ? 224 LYS A O   1 
ATOM   1674 C CB  . LYS A 1 223 ? -5.34984  59.66683 -23.23446 1.000 25.45936 ? 224 LYS A CB  1 
ATOM   1675 C CG  . LYS A 1 223 ? -6.84637  59.86259 -23.20957 1.000 31.34577 ? 224 LYS A CG  1 
ATOM   1676 C CD  . LYS A 1 223 ? -7.31825  60.53319 -24.46367 1.000 30.66431 ? 224 LYS A CD  1 
ATOM   1677 C CE  . LYS A 1 223 ? -8.76457  60.15768 -24.75627 1.000 36.94966 ? 224 LYS A CE  1 
ATOM   1678 N NZ  . LYS A 1 223 ? -9.08450  60.43174 -26.18216 1.000 44.26299 ? 224 LYS A NZ  1 
ATOM   1679 N N   . PRO A 1 224 ? -2.55177  60.08610 -24.54348 1.000 28.12235 ? 225 PRO A N   1 
ATOM   1680 C CA  . PRO A 1 224 ? -1.11661  60.01170 -24.23359 1.000 27.26832 ? 225 PRO A CA  1 
ATOM   1681 C C   . PRO A 1 224 ? -0.85748  59.52399 -22.82418 1.000 23.30707 ? 225 PRO A C   1 
ATOM   1682 O O   . PRO A 1 224 ? 0.16680   58.87028 -22.57262 1.000 23.86382 ? 225 PRO A O   1 
ATOM   1683 C CB  . PRO A 1 224 ? -0.64037  61.46291 -24.43388 1.000 26.26573 ? 225 PRO A CB  1 
ATOM   1684 C CG  . PRO A 1 224 ? -1.64339  62.05831 -25.37604 1.000 29.60992 ? 225 PRO A CG  1 
ATOM   1685 C CD  . PRO A 1 224 ? -2.95239  61.39562 -25.08591 1.000 26.08140 ? 225 PRO A CD  1 
ATOM   1686 N N   . ASN A 1 225 ? -1.77747  59.80591 -21.89980 1.000 25.44313 ? 226 ASN A N   1 
ATOM   1687 C CA  . ASN A 1 225 ? -1.56964  59.51468 -20.48589 1.000 25.94045 ? 226 ASN A CA  1 
ATOM   1688 C C   . ASN A 1 225 ? -1.32269  58.02900 -20.25108 1.000 25.71172 ? 226 ASN A C   1 
ATOM   1689 O O   . ASN A 1 225 ? -1.84621  57.16901 -20.96379 1.000 24.29149 ? 226 ASN A O   1 
ATOM   1690 C CB  . ASN A 1 225 ? -2.78830  59.97174 -19.68264 1.000 27.57000 ? 226 ASN A CB  1 
ATOM   1691 C CG  . ASN A 1 225 ? -3.13683  61.40969 -19.95655 1.000 31.94956 ? 226 ASN A CG  1 
ATOM   1692 O OD1 . ASN A 1 225 ? -3.57006  61.75570 -21.05929 1.000 29.57397 ? 226 ASN A OD1 1 
ATOM   1693 N ND2 . ASN A 1 225 ? -2.91784  62.26766 -18.96859 1.000 35.34233 ? 226 ASN A ND2 1 
ATOM   1694 N N   . ARG A 1 226 ? -0.52597  57.73552 -19.22703 1.000 20.02075 ? 227 ARG A N   1 
ATOM   1695 C CA  . ARG A 1 226 ? -0.12964  56.37947 -18.88195 1.000 24.13365 ? 227 ARG A CA  1 
ATOM   1696 C C   . ARG A 1 226 ? -0.28139  56.14653 -17.39337 1.000 27.85773 ? 227 ARG A C   1 
ATOM   1697 O O   . ARG A 1 226 ? -0.13572  57.06672 -16.58672 1.000 26.41062 ? 227 ARG A O   1 
ATOM   1698 C CB  . ARG A 1 226 ? 1.33923   56.09114 -19.24891 1.000 24.83740 ? 227 ARG A CB  1 
ATOM   1699 C CG  . ARG A 1 226 ? 1.59610   56.14363 -20.72256 1.000 24.68965 ? 227 ARG A CG  1 
ATOM   1700 C CD  . ARG A 1 226 ? 3.08000   56.19656 -21.07460 1.000 22.54489 ? 227 ARG A CD  1 
ATOM   1701 N NE  . ARG A 1 226 ? 3.18125   56.23562 -22.52524 1.000 23.94775 ? 227 ARG A NE  1 
ATOM   1702 C CZ  . ARG A 1 226 ? 3.85015   55.34780 -23.25538 1.000 24.24612 ? 227 ARG A CZ  1 
ATOM   1703 N NH1 . ARG A 1 226 ? 4.52280   54.36114 -22.66771 1.000 22.98961 ? 227 ARG A NH1 1 
ATOM   1704 N NH2 . ARG A 1 226 ? 3.85479   55.46462 -24.56901 1.000 21.66542 ? 227 ARG A NH2 1 
ATOM   1705 N N   . THR A 1 227 ? -0.53941  54.89225 -17.04757 1.000 25.72964 ? 228 THR A N   1 
ATOM   1706 C CA  . THR A 1 227 ? -0.47444  54.39417 -15.68354 1.000 26.53348 ? 228 THR A CA  1 
ATOM   1707 C C   . THR A 1 227 ? 0.50635   53.23218 -15.66860 1.000 29.27042 ? 228 THR A C   1 
ATOM   1708 O O   . THR A 1 227 ? 0.36868   52.28890 -16.46362 1.000 24.78415 ? 228 THR A O   1 
ATOM   1709 C CB  . THR A 1 227 ? -1.86254  53.95113 -15.18958 1.000 25.70170 ? 228 THR A CB  1 
ATOM   1710 O OG1 . THR A 1 227 ? -2.76368  55.06472 -15.22751 1.000 26.45087 ? 228 THR A OG1 1 
ATOM   1711 C CG2 . THR A 1 227 ? -1.79596  53.39043 -13.79444 1.000 23.93481 ? 228 THR A CG2 1 
ATOM   1712 N N   . SER A 1 228 ? 1.50186   53.30265 -14.78614 1.000 25.25371 ? 229 SER A N   1 
ATOM   1713 C CA  . SER A 1 228 ? 2.46759   52.21374 -14.70323 1.000 26.92586 ? 229 SER A CA  1 
ATOM   1714 C C   . SER A 1 228 ? 1.78074   50.91045 -14.29262 1.000 27.01433 ? 229 SER A C   1 
ATOM   1715 O O   . SER A 1 228 ? 0.70699   50.90310 -13.68002 1.000 26.05678 ? 229 SER A O   1 
ATOM   1716 C CB  . SER A 1 228 ? 3.56489   52.53673 -13.68897 1.000 28.75004 ? 229 SER A CB  1 
ATOM   1717 O OG  . SER A 1 228 ? 3.07871   52.34051 -12.37345 1.000 28.94071 ? 229 SER A OG  1 
ATOM   1718 N N   . VAL A 1 229 ? 2.43391   49.78952 -14.60555 1.000 25.70003 ? 230 VAL A N   1 
ATOM   1719 C CA  . VAL A 1 229 ? 1.89696   48.49898 -14.17489 1.000 25.67366 ? 230 VAL A CA  1 
ATOM   1720 C C   . VAL A 1 229 ? 1.78425   48.44222 -12.65254 1.000 28.17006 ? 230 VAL A C   1 
ATOM   1721 O O   . VAL A 1 229 ? 0.77092   47.98178 -12.10462 1.000 25.16910 ? 230 VAL A O   1 
ATOM   1722 C CB  . VAL A 1 229 ? 2.75852   47.34821 -14.72849 1.000 26.39785 ? 230 VAL A CB  1 
ATOM   1723 C CG1 . VAL A 1 229 ? 2.45631   46.05163 -13.97287 1.000 24.69426 ? 230 VAL A CG1 1 
ATOM   1724 C CG2 . VAL A 1 229 ? 2.52613   47.19796 -16.22454 1.000 25.61896 ? 230 VAL A CG2 1 
ATOM   1725 N N   . VAL A 1 230 ? 2.79725   48.94391 -11.94030 1.000 29.47319 ? 231 VAL A N   1 
ATOM   1726 C CA  . VAL A 1 230 ? 2.76766   48.83161 -10.48281 1.000 32.43313 ? 231 VAL A CA  1 
ATOM   1727 C C   . VAL A 1 230 ? 1.64411   49.68197 -9.90270  1.000 27.97693 ? 231 VAL A C   1 
ATOM   1728 O O   . VAL A 1 230 ? 0.94922   49.26363 -8.97069  1.000 29.07396 ? 231 VAL A O   1 
ATOM   1729 C CB  . VAL A 1 230 ? 4.14175   49.19218 -9.88020  1.000 35.63003 ? 231 VAL A CB  1 
ATOM   1730 C CG1 . VAL A 1 230 ? 4.67350   50.44927 -10.49412 1.000 39.57510 ? 231 VAL A CG1 1 
ATOM   1731 C CG2 . VAL A 1 230 ? 4.04167   49.35244 -8.36367  1.000 37.97927 ? 231 VAL A CG2 1 
ATOM   1732 N N   . SER A 1 231 ? 1.43752   50.87643 -10.45176 1.000 28.18250 ? 232 SER A N   1 
ATOM   1733 C CA  . SER A 1 231 ? 0.37385   51.74156 -9.95557  1.000 31.87527 ? 232 SER A CA  1 
ATOM   1734 C C   . SER A 1 231 ? -1.00373  51.20545 -10.34271 1.000 28.13118 ? 232 SER A C   1 
ATOM   1735 O O   . SER A 1 231 ? -1.94432  51.26006 -9.53720  1.000 27.55683 ? 232 SER A O   1 
ATOM   1736 C CB  . SER A 1 231 ? 0.58494   53.16308 -10.47303 1.000 28.88868 ? 232 SER A CB  1 
ATOM   1737 O OG  . SER A 1 231 ? -0.60226  53.92038 -10.38828 1.000 35.36933 ? 232 SER A OG  1 
ATOM   1738 N N   . PHE A 1 232 ? -1.14378  50.66221 -11.56270 1.000 25.80950 ? 233 PHE A N   1 
ATOM   1739 C CA  . PHE A 1 232 ? -2.39759  49.99712 -11.91916 1.000 26.57834 ? 233 PHE A CA  1 
ATOM   1740 C C   . PHE A 1 232 ? -2.71322  48.86372 -10.95441 1.000 24.30100 ? 233 PHE A C   1 
ATOM   1741 O O   . PHE A 1 232 ? -3.85939  48.70818 -10.51315 1.000 25.82036 ? 233 PHE A O   1 
ATOM   1742 C CB  . PHE A 1 232 ? -2.36314  49.44712 -13.34591 1.000 20.33558 ? 233 PHE A CB  1 
ATOM   1743 C CG  . PHE A 1 232 ? -3.64683  48.73767 -13.73880 1.000 21.49210 ? 233 PHE A CG  1 
ATOM   1744 C CD1 . PHE A 1 232 ? -4.71249  49.45300 -14.26600 1.000 23.19919 ? 233 PHE A CD1 1 
ATOM   1745 C CD2 . PHE A 1 232 ? -3.78725  47.36487 -13.56260 1.000 23.10053 ? 233 PHE A CD2 1 
ATOM   1746 C CE1 . PHE A 1 232 ? -5.90157  48.81387 -14.62846 1.000 23.61844 ? 233 PHE A CE1 1 
ATOM   1747 C CE2 . PHE A 1 232 ? -4.97109  46.71715 -13.91830 1.000 24.40727 ? 233 PHE A CE2 1 
ATOM   1748 C CZ  . PHE A 1 232 ? -6.03001  47.44431 -14.45001 1.000 21.95726 ? 233 PHE A CZ  1 
ATOM   1749 N N   . ASN A 1 233 ? -1.71483  48.03722 -10.63693 1.000 24.07674 ? 234 ASN A N   1 
ATOM   1750 C CA  . ASN A 1 233 ? -1.98513  46.89778 -9.77093  1.000 24.82970 ? 234 ASN A CA  1 
ATOM   1751 C C   . ASN A 1 233 ? -2.40210  47.34049 -8.36767  1.000 30.58530 ? 234 ASN A C   1 
ATOM   1752 O O   . ASN A 1 233 ? -3.20683  46.65997 -7.72413  1.000 29.97814 ? 234 ASN A O   1 
ATOM   1753 C CB  . ASN A 1 233 ? -0.77009  45.97228 -9.74256  1.000 27.14426 ? 234 ASN A CB  1 
ATOM   1754 C CG  . ASN A 1 233 ? -0.69204  45.12487 -10.99785 1.000 28.05558 ? 234 ASN A CG  1 
ATOM   1755 O OD1 . ASN A 1 233 ? -1.68863  45.01217 -11.71609 1.000 26.33520 ? 234 ASN A OD1 1 
ATOM   1756 N ND2 . ASN A 1 233 ? 0.47469   44.56084 -11.29112 1.000 27.07654 ? 234 ASN A ND2 1 
ATOM   1757 N N   . GLU A 1 234 ? -1.90712  48.48764 -7.88792  1.000 28.73159 ? 235 GLU A N   1 
ATOM   1758 C CA  . GLU A 1 234 ? -2.41853  49.02803 -6.62574  1.000 31.12661 ? 235 GLU A CA  1 
ATOM   1759 C C   . GLU A 1 234 ? -3.87866  49.44034 -6.76330  1.000 28.75751 ? 235 GLU A C   1 
ATOM   1760 O O   . GLU A 1 234 ? -4.71352  49.12259 -5.91023  1.000 29.90965 ? 235 GLU A O   1 
ATOM   1761 C CB  . GLU A 1 234 ? -1.57440  50.22379 -6.17464  1.000 34.51574 ? 235 GLU A CB  1 
ATOM   1762 C CG  . GLU A 1 234 ? -0.32453  49.85668 -5.39791  1.000 41.17545 ? 235 GLU A CG  1 
ATOM   1763 C CD  . GLU A 1 234 ? 0.71546   50.97611 -5.40327  1.000 49.06729 ? 235 GLU A CD  1 
ATOM   1764 O OE1 . GLU A 1 234 ? 0.33595   52.14627 -5.65224  1.000 47.36633 ? 235 GLU A OE1 1 
ATOM   1765 O OE2 . GLU A 1 234 ? 1.90923   50.68311 -5.15956  1.000 48.66076 ? 235 GLU A OE2 1 
ATOM   1766 N N   . TRP A 1 235 ? -4.20632  50.15812 -7.83735  1.000 26.98584 ? 236 TRP A N   1 
ATOM   1767 C CA  . TRP A 1 235 ? -5.59263  50.55167 -8.06401  1.000 26.98998 ? 236 TRP A CA  1 
ATOM   1768 C C   . TRP A 1 235 ? -6.50074  49.32700 -8.22932  1.000 28.55581 ? 236 TRP A C   1 
ATOM   1769 O O   . TRP A 1 235 ? -7.64469  49.32013 -7.75906  1.000 28.39805 ? 236 TRP A O   1 
ATOM   1770 C CB  . TRP A 1 235 ? -5.63979  51.46885 -9.28286  1.000 22.89878 ? 236 TRP A CB  1 
ATOM   1771 C CG  . TRP A 1 235 ? -6.98935  51.83602 -9.78237  1.000 26.74625 ? 236 TRP A CG  1 
ATOM   1772 C CD1 . TRP A 1 235 ? -7.69979  52.95869 -9.47381  1.000 27.91314 ? 236 TRP A CD1 1 
ATOM   1773 C CD2 . TRP A 1 235 ? -7.78178  51.10109 -10.71721 1.000 28.28036 ? 236 TRP A CD2 1 
ATOM   1774 N NE1 . TRP A 1 235 ? -8.89641  52.95881 -10.14705 1.000 28.60935 ? 236 TRP A NE1 1 
ATOM   1775 C CE2 . TRP A 1 235 ? -8.97209  51.82548 -10.91456 1.000 30.02387 ? 236 TRP A CE2 1 
ATOM   1776 C CE3 . TRP A 1 235 ? -7.60911  49.88641 -11.39119 1.000 26.54566 ? 236 TRP A CE3 1 
ATOM   1777 C CZ2 . TRP A 1 235 ? -9.97784  51.38412 -11.76549 1.000 30.53275 ? 236 TRP A CZ2 1 
ATOM   1778 C CZ3 . TRP A 1 235 ? -8.60205  49.44984 -12.22027 1.000 26.15814 ? 236 TRP A CZ3 1 
ATOM   1779 C CH2 . TRP A 1 235 ? -9.77661  50.19703 -12.40806 1.000 29.51121 ? 236 TRP A CH2 1 
ATOM   1780 N N   . ALA A 1 236 ? -5.99650  48.26791 -8.86805  1.000 24.63163 ? 237 ALA A N   1 
ATOM   1781 C CA  . ALA A 1 236 ? -6.83080  47.09843 -9.13366  1.000 27.60787 ? 237 ALA A CA  1 
ATOM   1782 C C   . ALA A 1 236 ? -7.28661  46.42958 -7.83742  1.000 28.03949 ? 237 ALA A C   1 
ATOM   1783 O O   . ALA A 1 236 ? -8.43344  45.98452 -7.73577  1.000 26.11543 ? 237 ALA A O   1 
ATOM   1784 C CB  . ALA A 1 236 ? -6.07522  46.10203 -10.02259 1.000 24.55232 ? 237 ALA A CB  1 
ATOM   1785 N N   . LEU A 1 237 ? -6.40559  46.36832 -6.83130  1.000 32.85774 ? 238 LEU A N   1 
ATOM   1786 C CA  . LEU A 1 237 ? -6.76722  45.78892 -5.53450  1.000 34.88356 ? 238 LEU A CA  1 
ATOM   1787 C C   . LEU A 1 237 ? -7.99153  46.45613 -4.91991  1.000 33.26821 ? 238 LEU A C   1 
ATOM   1788 O O   . LEU A 1 237 ? -8.71973  45.82381 -4.14643  1.000 32.84837 ? 238 LEU A O   1 
ATOM   1789 C CB  . LEU A 1 237 ? -5.59560  45.90453 -4.55333  1.000 32.73064 ? 238 LEU A CB  1 
ATOM   1790 C CG  . LEU A 1 237 ? -4.42990  44.90756 -4.55500  1.000 34.87118 ? 238 LEU A CG  1 
ATOM   1791 C CD1 . LEU A 1 237 ? -4.82870  43.52793 -4.04825  1.000 37.87368 ? 238 LEU A CD1 1 
ATOM   1792 C CD2 . LEU A 1 237 ? -3.80312  44.79716 -5.90144  1.000 44.79912 ? 238 LEU A CD2 1 
ATOM   1793 N N   . ALA A 1 238 ? -8.22422  47.72906 -5.23357  1.000 32.34771 ? 239 ALA A N   1 
ATOM   1794 C CA  . ALA A 1 238 ? -9.32795  48.49747 -4.67790  1.000 33.24106 ? 239 ALA A CA  1 
ATOM   1795 C C   . ALA A 1 238 ? -10.53808 48.56083 -5.59714  1.000 33.37298 ? 239 ALA A C   1 
ATOM   1796 O O   . ALA A 1 238 ? -11.55840 49.14346 -5.21651  1.000 34.36730 ? 239 ALA A O   1 
ATOM   1797 C CB  . ALA A 1 238 ? -8.86664  49.92229 -4.34865  1.000 32.40989 ? 239 ALA A CB  1 
ATOM   1798 N N   . ASN A 1 239 ? -10.47022 47.97798 -6.79641  1.000 31.86804 ? 240 ASN A N   1 
ATOM   1799 C CA  . ASN A 1 239 ? -11.57952 48.13261 -7.72869  1.000 29.41093 ? 240 ASN A CA  1 
ATOM   1800 C C   . ASN A 1 239 ? -11.99840 46.82487 -8.39631  1.000 26.84726 ? 240 ASN A C   1 
ATOM   1801 O O   . ASN A 1 239 ? -12.65748 46.86139 -9.43628  1.000 32.82850 ? 240 ASN A O   1 
ATOM   1802 C CB  . ASN A 1 239 ? -11.22441 49.18566 -8.77354  1.000 29.85529 ? 240 ASN A CB  1 
ATOM   1803 C CG  . ASN A 1 239 ? -11.12724 50.58256 -8.17725  1.000 30.10087 ? 240 ASN A CG  1 
ATOM   1804 O OD1 . ASN A 1 239 ? -12.11507 51.30622 -8.11084  1.000 33.22489 ? 240 ASN A OD1 1 
ATOM   1805 N ND2 . ASN A 1 239 ? -9.94064  50.94915 -7.71315  1.000 29.06082 ? 240 ASN A ND2 1 
ATOM   1806 N N   . GLN A 1 240 ? -11.67041 45.67896 -7.79963  1.000 32.06191 ? 241 GLN A N   1 
ATOM   1807 C CA  . GLN A 1 240 ? -12.06533 44.36160 -8.31329  1.000 32.65330 ? 241 GLN A CA  1 
ATOM   1808 C C   . GLN A 1 240 ? -11.58290 44.14851 -9.75188  1.000 28.00820 ? 241 GLN A C   1 
ATOM   1809 O O   . GLN A 1 240 ? -12.32835 43.70652 -10.62761 1.000 26.85728 ? 241 GLN A O   1 
ATOM   1810 C CB  . GLN A 1 240 ? -13.58032 44.13884 -8.20132  1.000 32.53898 ? 241 GLN A CB  1 
ATOM   1811 C CG  . GLN A 1 240 ? -14.05659 43.96696 -6.76574  1.000 41.10724 ? 241 GLN A CG  1 
ATOM   1812 C CD  . GLN A 1 240 ? -15.55579 44.12483 -6.61688  1.000 51.91735 ? 241 GLN A CD  1 
ATOM   1813 O OE1 . GLN A 1 240 ? -16.08728 44.03380 -5.51010  1.000 54.92559 ? 241 GLN A OE1 1 
ATOM   1814 N NE2 . GLN A 1 240 ? -16.25019 44.35163 -7.73185  1.000 50.64397 ? 241 GLN A NE2 1 
ATOM   1815 N N   . PHE A 1 241 ? -10.31622 44.45954 -9.98455  1.000 28.62882 ? 242 PHE A N   1 
ATOM   1816 C CA  . PHE A 1 241 ? -9.60287  44.00155 -11.16882 1.000 27.45965 ? 242 PHE A CA  1 
ATOM   1817 C C   . PHE A 1 241 ? -8.50135  43.04957 -10.71962 1.000 29.55871 ? 242 PHE A C   1 
ATOM   1818 O O   . PHE A 1 241 ? -7.97174  43.17721 -9.61205  1.000 24.74196 ? 242 PHE A O   1 
ATOM   1819 C CB  . PHE A 1 241 ? -8.99233  45.16938 -11.95190 1.000 24.97494 ? 242 PHE A CB  1 
ATOM   1820 C CG  . PHE A 1 241 ? -9.95927  45.86938 -12.87279 1.000 28.01115 ? 242 PHE A CG  1 
ATOM   1821 C CD1 . PHE A 1 241 ? -10.97644 46.66720 -12.36653 1.000 27.52390 ? 242 PHE A CD1 1 
ATOM   1822 C CD2 . PHE A 1 241 ? -9.82379  45.76015 -14.24496 1.000 25.03295 ? 242 PHE A CD2 1 
ATOM   1823 C CE1 . PHE A 1 241 ? -11.86208 47.32016 -13.21758 1.000 29.42391 ? 242 PHE A CE1 1 
ATOM   1824 C CE2 . PHE A 1 241 ? -10.69575 46.40738 -15.09615 1.000 22.56952 ? 242 PHE A CE2 1 
ATOM   1825 C CZ  . PHE A 1 241 ? -11.71813 47.18463 -14.58983 1.000 25.89766 ? 242 PHE A CZ  1 
ATOM   1826 N N   . THR A 1 242 ? -8.18120  42.07214 -11.56889 1.000 24.43116 ? 243 THR A N   1 
ATOM   1827 C CA  . THR A 1 242 ? -7.04222  41.22023 -11.29151 1.000 23.98891 ? 243 THR A CA  1 
ATOM   1828 C C   . THR A 1 242 ? -5.74088  41.98866 -11.45891 1.000 24.69199 ? 243 THR A C   1 
ATOM   1829 O O   . THR A 1 242 ? -5.66362  43.00182 -12.16291 1.000 24.94356 ? 243 THR A O   1 
ATOM   1830 C CB  . THR A 1 242 ? -7.00360  40.01503 -12.23274 1.000 25.42235 ? 243 THR A CB  1 
ATOM   1831 O OG1 . THR A 1 242 ? -6.87358  40.48414 -13.58555 1.000 22.26488 ? 243 THR A OG1 1 
ATOM   1832 C CG2 . THR A 1 242 ? -8.25806  39.17198 -12.07587 1.000 25.69455 ? 243 THR A CG2 1 
ATOM   1833 N N   . GLU A 1 243 ? -4.69189  41.44409 -10.84935 1.000 23.97361 ? 244 GLU A N   1 
ATOM   1834 C CA  . GLU A 1 243 ? -3.34558  41.92611 -11.10179 1.000 29.79641 ? 244 GLU A CA  1 
ATOM   1835 C C   . GLU A 1 243 ? -2.97393  41.73784 -12.56944 1.000 30.57439 ? 244 GLU A C   1 
ATOM   1836 O O   . GLU A 1 243 ? -3.13947  40.64526 -13.12858 1.000 28.52555 ? 244 GLU A O   1 
ATOM   1837 C CB  . GLU A 1 243 ? -2.36096  41.17807 -10.21914 1.000 29.14750 ? 244 GLU A CB  1 
ATOM   1838 C CG  . GLU A 1 243 ? -0.93596  41.44022 -10.60300 1.000 34.01884 ? 244 GLU A CG  1 
ATOM   1839 C CD  . GLU A 1 243 ? 0.00402   40.43921 -9.98134  1.000 40.20951 ? 244 GLU A CD  1 
ATOM   1840 O OE1 . GLU A 1 243 ? -0.48118  39.36507 -9.55752  1.000 44.73499 ? 244 GLU A OE1 1 
ATOM   1841 O OE2 . GLU A 1 243 ? 1.21619   40.73323 -9.90978  1.000 39.66473 ? 244 GLU A OE2 1 
ATOM   1842 N N   . PHE A 1 244 ? -2.48075  42.80826 -13.19865 1.000 26.68982 ? 245 PHE A N   1 
ATOM   1843 C CA  . PHE A 1 244 ? -2.04114  42.73139 -14.58803 1.000 26.93804 ? 245 PHE A CA  1 
ATOM   1844 C C   . PHE A 1 244 ? -0.64529  42.12544 -14.65085 1.000 28.91799 ? 245 PHE A C   1 
ATOM   1845 O O   . PHE A 1 244 ? 0.29475   42.63581 -14.02984 1.000 27.50240 ? 245 PHE A O   1 
ATOM   1846 C CB  . PHE A 1 244 ? -2.04451  44.10182 -15.26511 1.000 24.71445 ? 245 PHE A CB  1 
ATOM   1847 C CG  . PHE A 1 244 ? -1.51016  44.06744 -16.68556 1.000 23.55935 ? 245 PHE A CG  1 
ATOM   1848 C CD1 . PHE A 1 244 ? -2.36120  43.82095 -17.74993 1.000 23.63290 ? 245 PHE A CD1 1 
ATOM   1849 C CD2 . PHE A 1 244 ? -0.16135  44.25191 -16.94263 1.000 24.73387 ? 245 PHE A CD2 1 
ATOM   1850 C CE1 . PHE A 1 244 ? -1.88939  43.76811 -19.05371 1.000 23.14357 ? 245 PHE A CE1 1 
ATOM   1851 C CE2 . PHE A 1 244 ? 0.33182   44.19755 -18.23600 1.000 24.79266 ? 245 PHE A CE2 1 
ATOM   1852 C CZ  . PHE A 1 244 ? -0.54140  43.95332 -19.30212 1.000 26.12050 ? 245 PHE A CZ  1 
ATOM   1853 N N   . VAL A 1 245 ? -0.51146  41.04630 -15.41356 1.000 24.15073 ? 246 VAL A N   1 
ATOM   1854 C CA  . VAL A 1 245 ? 0.76851   40.40905 -15.68335 1.000 26.77955 ? 246 VAL A CA  1 
ATOM   1855 C C   . VAL A 1 245 ? 0.91798   40.36479 -17.19834 1.000 27.53130 ? 246 VAL A C   1 
ATOM   1856 O O   . VAL A 1 245 ? 0.12444   39.70426 -17.88657 1.000 27.48019 ? 246 VAL A O   1 
ATOM   1857 C CB  . VAL A 1 245 ? 0.83992   39.00122 -15.06557 1.000 30.42417 ? 246 VAL A CB  1 
ATOM   1858 C CG1 . VAL A 1 245 ? 2.20541   38.37471 -15.28635 1.000 30.53149 ? 246 VAL A CG1 1 
ATOM   1859 C CG2 . VAL A 1 245 ? 0.52050   39.07107 -13.58661 1.000 35.61443 ? 246 VAL A CG2 1 
ATOM   1860 N N   . GLY A 1 246 ? 1.90074   41.09396 -17.71690 1.000 27.59331 ? 247 GLY A N   1 
ATOM   1861 C CA  . GLY A 1 246 ? 2.11621   41.12589 -19.14652 1.000 28.81963 ? 247 GLY A CA  1 
ATOM   1862 C C   . GLY A 1 246 ? 2.66463   39.81516 -19.67719 1.000 28.75141 ? 247 GLY A C   1 
ATOM   1863 O O   . GLY A 1 246 ? 3.24231   39.00867 -18.95188 1.000 27.27790 ? 247 GLY A O   1 
ATOM   1864 N N   . THR A 1 247 ? 2.45100   39.58785 -20.97538 1.000 27.08172 ? 248 THR A N   1 
ATOM   1865 C CA  . THR A 1 247 ? 2.93298   38.38648 -21.63913 1.000 27.19323 ? 248 THR A CA  1 
ATOM   1866 C C   . THR A 1 247 ? 3.47186   38.76056 -23.00960 1.000 27.96099 ? 248 THR A C   1 
ATOM   1867 O O   . THR A 1 247 ? 3.22109   39.85282 -23.52537 1.000 23.77907 ? 248 THR A O   1 
ATOM   1868 C CB  . THR A 1 247 ? 1.83663   37.31778 -21.79819 1.000 24.04225 ? 248 THR A CB  1 
ATOM   1869 O OG1 . THR A 1 247 ? 0.87869   37.76345 -22.75917 1.000 25.41526 ? 248 THR A OG1 1 
ATOM   1870 C CG2 . THR A 1 247 ? 1.14065   37.03524 -20.48782 1.000 27.01678 ? 248 THR A CG2 1 
ATOM   1871 N N   . GLN A 1 248 ? 4.21469   37.82585 -23.61037 1.000 26.20287 ? 249 GLN A N   1 
ATOM   1872 C CA  . GLN A 1 248 ? 4.69719   38.04129 -24.96893 1.000 27.81740 ? 249 GLN A CA  1 
ATOM   1873 C C   . GLN A 1 248 ? 3.54090   38.23374 -25.93483 1.000 26.59905 ? 249 GLN A C   1 
ATOM   1874 O O   . GLN A 1 248 ? 3.66896   38.97521 -26.91396 1.000 24.92555 ? 249 GLN A O   1 
ATOM   1875 C CB  . GLN A 1 248 ? 5.58767   36.87415 -25.40800 1.000 34.12645 ? 249 GLN A CB  1 
ATOM   1876 C CG  . GLN A 1 248 ? 6.97392   36.89017 -24.74004 1.000 41.29431 ? 249 GLN A CG  1 
ATOM   1877 C CD  . GLN A 1 248 ? 7.72594   35.55859 -24.83339 1.000 51.82724 ? 249 GLN A CD  1 
ATOM   1878 O OE1 . GLN A 1 248 ? 7.49476   34.64091 -24.03936 1.000 50.04050 ? 249 GLN A OE1 1 
ATOM   1879 N NE2 . GLN A 1 248 ? 8.64669   35.46388 -25.78898 1.000 51.39091 ? 249 GLN A NE2 1 
ATOM   1880 N N   . SER A 1 249 ? 2.39544   37.60278 -25.66113 1.000 23.82825 ? 250 SER A N   1 
ATOM   1881 C CA  . SER A 1 249 ? 1.22272   37.80098 -26.50727 1.000 23.86013 ? 250 SER A CA  1 
ATOM   1882 C C   . SER A 1 249 ? 0.74258   39.25519 -26.45118 1.000 23.75746 ? 250 SER A C   1 
ATOM   1883 O O   . SER A 1 249 ? 0.42563   39.86473 -27.48267 1.000 22.30493 ? 250 SER A O   1 
ATOM   1884 C CB  . SER A 1 249 ? 0.11749   36.83673 -26.06409 1.000 25.29384 ? 250 SER A CB  1 
ATOM   1885 O OG  . SER A 1 249 ? -0.91245  36.73520 -27.02779 1.000 28.38603 ? 250 SER A OG  1 
ATOM   1886 N N   . VAL A 1 250 ? 0.66382   39.82402 -25.24756 1.000 24.46818 ? 251 VAL A N   1 
ATOM   1887 C CA  . VAL A 1 250 ? 0.29180   41.23594 -25.12613 1.000 23.98666 ? 251 VAL A CA  1 
ATOM   1888 C C   . VAL A 1 250 ? 1.31840   42.12944 -25.82151 1.000 21.28294 ? 251 VAL A C   1 
ATOM   1889 O O   . VAL A 1 250 ? 0.96249   43.08100 -26.52047 1.000 20.28237 ? 251 VAL A O   1 
ATOM   1890 C CB  . VAL A 1 250 ? 0.13386   41.62996 -23.64639 1.000 25.75161 ? 251 VAL A CB  1 
ATOM   1891 C CG1 . VAL A 1 250 ? -0.21665  43.10673 -23.54928 1.000 22.33153 ? 251 VAL A CG1 1 
ATOM   1892 C CG2 . VAL A 1 250 ? -0.93721  40.77968 -22.96561 1.000 22.07858 ? 251 VAL A CG2 1 
ATOM   1893 N N   . ASP A 1 251 ? 2.60493   41.84182 -25.63418 1.000 24.63415 ? 252 ASP A N   1 
ATOM   1894 C CA  . ASP A 1 251 ? 3.64394   42.67916 -26.23060 1.000 25.19843 ? 252 ASP A CA  1 
ATOM   1895 C C   . ASP A 1 251 ? 3.53675   42.72997 -27.75201 1.000 26.14255 ? 252 ASP A C   1 
ATOM   1896 O O   . ASP A 1 251 ? 3.88692   43.74440 -28.36484 1.000 26.02615 ? 252 ASP A O   1 
ATOM   1897 C CB  . ASP A 1 251 ? 5.02484   42.15763 -25.82352 1.000 27.55778 ? 252 ASP A CB  1 
ATOM   1898 C CG  . ASP A 1 251 ? 5.26984   42.21872 -24.31516 1.000 31.92072 ? 252 ASP A CG  1 
ATOM   1899 O OD1 . ASP A 1 251 ? 4.61475   43.03187 -23.61855 1.000 31.43970 ? 252 ASP A OD1 1 
ATOM   1900 O OD2 . ASP A 1 251 ? 6.13638   41.45056 -23.82570 1.000 31.22330 ? 252 ASP A OD2 1 
ATOM   1901 N N   . MET A 1 252 ? 3.08765   41.64082 -28.38683 1.000 24.71844 ? 253 MET A N   1 
ATOM   1902 C CA  . MET A 1 252 ? 2.92985   41.64842 -29.83927 1.000 25.79621 ? 253 MET A CA  1 
ATOM   1903 C C   . MET A 1 252 ? 1.88577   42.66170 -30.28182 1.000 22.15537 ? 253 MET A C   1 
ATOM   1904 O O   . MET A 1 252 ? 2.05264   43.32687 -31.30914 1.000 21.41322 ? 253 MET A O   1 
ATOM   1905 C CB  . MET A 1 252 ? 2.53033   40.26096 -30.33364 1.000 28.11503 ? 253 MET A CB  1 
ATOM   1906 C CG  . MET A 1 252 ? 3.58870   39.20303 -30.14814 1.000 35.05295 ? 253 MET A CG  1 
ATOM   1907 S SD  . MET A 1 252 ? 3.08458   37.72664 -31.04237 1.000 49.13012 ? 253 MET A SD  1 
ATOM   1908 C CE  . MET A 1 252 ? 3.52304   38.23196 -32.69974 1.000 39.06928 ? 253 MET A CE  1 
ATOM   1909 N N   . LEU A 1 253 ? 0.79170   42.77441 -29.52736 1.000 23.24554 ? 254 LEU A N   1 
ATOM   1910 C CA  . LEU A 1 253 ? -0.24421  43.75451 -29.83373 1.000 21.18343 ? 254 LEU A CA  1 
ATOM   1911 C C   . LEU A 1 253 ? 0.26052   45.18252 -29.62880 1.000 20.68435 ? 254 LEU A C   1 
ATOM   1912 O O   . LEU A 1 253 ? -0.03229  46.07507 -30.43767 1.000 23.51976 ? 254 LEU A O   1 
ATOM   1913 C CB  . LEU A 1 253 ? -1.47988  43.47775 -28.96581 1.000 20.37902 ? 254 LEU A CB  1 
ATOM   1914 C CG  . LEU A 1 253 ? -2.07635  42.06671 -29.11498 1.000 20.00181 ? 254 LEU A CG  1 
ATOM   1915 C CD1 . LEU A 1 253 ? -3.05061  41.69475 -27.96765 1.000 22.31999 ? 254 LEU A CD1 1 
ATOM   1916 C CD2 . LEU A 1 253 ? -2.76856  41.94785 -30.46633 1.000 21.13646 ? 254 LEU A CD2 1 
ATOM   1917 N N   . ALA A 1 254 ? 1.02955   45.41280 -28.56384 1.000 21.31472 ? 255 ALA A N   1 
ATOM   1918 C CA  . ALA A 1 254 ? 1.61638   46.73402 -28.32678 1.000 22.81443 ? 255 ALA A CA  1 
ATOM   1919 C C   . ALA A 1 254 ? 2.55758   47.13161 -29.45748 1.000 26.71948 ? 255 ALA A C   1 
ATOM   1920 O O   . ALA A 1 254 ? 2.49294   48.25595 -29.97580 1.000 24.03367 ? 255 ALA A O   1 
ATOM   1921 C CB  . ALA A 1 254 ? 2.36697   46.73795 -26.99127 1.000 21.17288 ? 255 ALA A CB  1 
ATOM   1922 N N   . VAL A 1 255 ? 3.44521   46.21634 -29.86096 1.000 26.62006 ? 256 VAL A N   1 
ATOM   1923 C CA  . VAL A 1 255 ? 4.32606   46.50641 -30.99329 1.000 25.10611 ? 256 VAL A CA  1 
ATOM   1924 C C   . VAL A 1 255 ? 3.50349   46.83684 -32.23025 1.000 26.79563 ? 256 VAL A C   1 
ATOM   1925 O O   . VAL A 1 255 ? 3.74058   47.85029 -32.90054 1.000 27.83237 ? 256 VAL A O   1 
ATOM   1926 C CB  . VAL A 1 255 ? 5.29038   45.33141 -31.25008 1.000 28.07416 ? 256 VAL A CB  1 
ATOM   1927 C CG1 . VAL A 1 255 ? 5.97486   45.47965 -32.62753 1.000 29.64495 ? 256 VAL A CG1 1 
ATOM   1928 C CG2 . VAL A 1 255 ? 6.30932   45.25092 -30.14668 1.000 30.24945 ? 256 VAL A CG2 1 
ATOM   1929 N N   . LYS A 1 256 ? 2.50025   46.00259 -32.53238 1.000 24.25236 ? 257 LYS A N   1 
ATOM   1930 C CA  . LYS A 1 256 ? 1.76596   46.15392 -33.78095 1.000 28.30999 ? 257 LYS A CA  1 
ATOM   1931 C C   . LYS A 1 256 ? 0.99412   47.46566 -33.82675 1.000 28.97184 ? 257 LYS A C   1 
ATOM   1932 O O   . LYS A 1 256 ? 1.01280   48.16259 -34.84740 1.000 29.54729 ? 257 LYS A O   1 
ATOM   1933 C CB  . LYS A 1 256 ? 0.82227   44.97452 -33.98761 1.000 27.73211 ? 257 LYS A CB  1 
ATOM   1934 C CG  . LYS A 1 256 ? -0.14361  45.14823 -35.14763 1.000 37.41770 ? 257 LYS A CG  1 
ATOM   1935 C CD  . LYS A 1 256 ? 0.55539   45.11030 -36.50268 1.000 39.84793 ? 257 LYS A CD  1 
ATOM   1936 C CE  . LYS A 1 256 ? -0.39928  44.57162 -37.56507 1.000 48.64722 ? 257 LYS A CE  1 
ATOM   1937 N NZ  . LYS A 1 256 ? -0.21994  45.23399 -38.89167 1.000 53.32436 ? 257 LYS A NZ  1 
ATOM   1938 N N   . THR A 1 257 ? 0.31484   47.82727 -32.73413 1.000 25.67064 ? 258 THR A N   1 
ATOM   1939 C CA  . THR A 1 257 ? -0.48331  49.04643 -32.72846 1.000 26.33452 ? 258 THR A CA  1 
ATOM   1940 C C   . THR A 1 257 ? 0.32891   50.30100 -32.43098 1.000 27.59104 ? 258 THR A C   1 
ATOM   1941 O O   . THR A 1 257 ? -0.12064  51.39699 -32.77173 1.000 28.11761 ? 258 THR A O   1 
ATOM   1942 C CB  . THR A 1 257 ? -1.61050  48.95334 -31.69952 1.000 21.45388 ? 258 THR A CB  1 
ATOM   1943 O OG1 . THR A 1 257 ? -1.04229  48.83776 -30.39886 1.000 21.43903 ? 258 THR A OG1 1 
ATOM   1944 C CG2 . THR A 1 257 ? -2.49841  47.72850 -31.96258 1.000 25.12090 ? 258 THR A CG2 1 
ATOM   1945 N N   . GLY A 1 258 ? 1.49062   50.17848 -31.78850 1.000 27.33808 ? 259 GLY A N   1 
ATOM   1946 C CA  . GLY A 1 258 ? 2.19097   51.36122 -31.33261 1.000 26.46006 ? 259 GLY A CA  1 
ATOM   1947 C C   . GLY A 1 258 ? 1.60419   51.99936 -30.09553 1.000 25.14720 ? 259 GLY A C   1 
ATOM   1948 O O   . GLY A 1 258 ? 2.06797   53.07150 -29.69216 1.000 25.80583 ? 259 GLY A O   1 
ATOM   1949 N N   . VAL A 1 259 ? 0.60421   51.37869 -29.48032 1.000 25.80684 ? 260 VAL A N   1 
ATOM   1950 C CA  . VAL A 1 259 ? 0.01264   51.86963 -28.24338 1.000 24.03653 ? 260 VAL A CA  1 
ATOM   1951 C C   . VAL A 1 259 ? 0.55933   51.02862 -27.09887 1.000 23.50623 ? 260 VAL A C   1 
ATOM   1952 O O   . VAL A 1 259 ? 0.46884   49.79124 -27.12112 1.000 23.75830 ? 260 VAL A O   1 
ATOM   1953 C CB  . VAL A 1 259 ? -1.51950  51.82680 -28.30708 1.000 23.62626 ? 260 VAL A CB  1 
ATOM   1954 C CG1 . VAL A 1 259 ? -2.12321  52.35611 -27.01657 1.000 23.50609 ? 260 VAL A CG1 1 
ATOM   1955 C CG2 . VAL A 1 259 ? -2.00305  52.63800 -29.49842 1.000 25.99924 ? 260 VAL A CG2 1 
ATOM   1956 N N   . ALA A 1 260 ? 1.15318   51.69465 -26.11296 1.000 19.56490 ? 261 ALA A N   1 
ATOM   1957 C CA  . ALA A 1 260 ? 1.78273   51.00938 -24.99582 1.000 24.96156 ? 261 ALA A CA  1 
ATOM   1958 C C   . ALA A 1 260 ? 0.74921   50.46436 -24.01408 1.000 24.76128 ? 261 ALA A C   1 
ATOM   1959 O O   . ALA A 1 260 ? -0.33059  51.04366 -23.82215 1.000 21.86553 ? 261 ALA A O   1 
ATOM   1960 C CB  . ALA A 1 260 ? 2.73143   51.94921 -24.24531 1.000 21.22569 ? 261 ALA A CB  1 
ATOM   1961 N N   . ILE A 1 261 ? 1.11935   49.35554 -23.36550 1.000 20.00377 ? 262 ILE A N   1 
ATOM   1962 C CA  . ILE A 1 261 ? 0.28266   48.74969 -22.32708 1.000 20.12905 ? 262 ILE A CA  1 
ATOM   1963 C C   . ILE A 1 261 ? -0.16548  49.79907 -21.31516 1.000 22.24223 ? 262 ILE A C   1 
ATOM   1964 O O   . ILE A 1 261 ? -1.34228  49.85717 -20.92647 1.000 20.31931 ? 262 ILE A O   1 
ATOM   1965 C CB  . ILE A 1 261 ? 1.04515   47.61015 -21.62871 1.000 22.18216 ? 262 ILE A CB  1 
ATOM   1966 C CG1 . ILE A 1 261 ? 1.14803   46.36811 -22.51222 1.000 22.01076 ? 262 ILE A CG1 1 
ATOM   1967 C CG2 . ILE A 1 261 ? 0.37491   47.22538 -20.31456 1.000 23.09366 ? 262 ILE A CG2 1 
ATOM   1968 C CD1 . ILE A 1 261 ? 2.20587   45.42210 -22.00314 1.000 21.57692 ? 262 ILE A CD1 1 
ATOM   1969 N N   . GLU A 1 262 ? 0.76701   50.65482 -20.88508 1.000 20.78002 ? 263 GLU A N   1 
ATOM   1970 C CA  . GLU A 1 262 ? 0.46327   51.64016 -19.84701 1.000 22.75535 ? 263 GLU A CA  1 
ATOM   1971 C C   . GLU A 1 262 ? -0.54741  52.68809 -20.31035 1.000 23.88510 ? 263 GLU A C   1 
ATOM   1972 O O   . GLU A 1 262 ? -1.23870  53.29378 -19.47548 1.000 26.34051 ? 263 GLU A O   1 
ATOM   1973 C CB  . GLU A 1 262 ? 1.75829   52.30502 -19.38265 1.000 22.93233 ? 263 GLU A CB  1 
ATOM   1974 C CG  . GLU A 1 262 ? 2.64773   51.37881 -18.56918 1.000 24.27926 ? 263 GLU A CG  1 
ATOM   1975 C CD  . GLU A 1 262 ? 3.59464   50.53441 -19.41759 1.000 28.39594 ? 263 GLU A CD  1 
ATOM   1976 O OE1 . GLU A 1 262 ? 3.55320   50.63311 -20.66749 1.000 31.24320 ? 263 GLU A OE1 1 
ATOM   1977 O OE2 . GLU A 1 262 ? 4.38292   49.76213 -18.82373 1.000 32.18021 ? 263 GLU A OE2 1 
ATOM   1978 N N   . GLN A 1 263 ? -0.63788  52.94638 -21.61232 1.000 20.71156 ? 264 GLN A N   1 
ATOM   1979 C CA  . GLN A 1 263 ? -1.72320  53.79524 -22.09735 1.000 20.06635 ? 264 GLN A CA  1 
ATOM   1980 C C   . GLN A 1 263 ? -3.07901  53.11778 -21.90780 1.000 23.34845 ? 264 GLN A C   1 
ATOM   1981 O O   . GLN A 1 263 ? -4.06928  53.77706 -21.56772 1.000 21.96178 ? 264 GLN A O   1 
ATOM   1982 C CB  . GLN A 1 263 ? -1.52418  54.13920 -23.56801 1.000 21.74285 ? 264 GLN A CB  1 
ATOM   1983 C CG  . GLN A 1 263 ? -0.37440  55.07859 -23.84617 1.000 23.98773 ? 264 GLN A CG  1 
ATOM   1984 C CD  . GLN A 1 263 ? -0.15561  55.28346 -25.32858 1.000 25.85632 ? 264 GLN A CD  1 
ATOM   1985 O OE1 . GLN A 1 263 ? 0.65024   54.58279 -25.93968 1.000 21.02488 ? 264 GLN A OE1 1 
ATOM   1986 N NE2 . GLN A 1 263 ? -0.87441  56.24296 -25.91896 1.000 22.93124 ? 264 GLN A NE2 1 
ATOM   1987 N N   . LEU A 1 264 ? -3.14922  51.80804 -22.15182 1.000 21.73180 ? 265 LEU A N   1 
ATOM   1988 C CA  . LEU A 1 264 ? -4.41912  51.10884 -21.98624 1.000 19.52238 ? 265 LEU A CA  1 
ATOM   1989 C C   . LEU A 1 264 ? -4.76092  50.91237 -20.51743 1.000 21.23653 ? 265 LEU A C   1 
ATOM   1990 O O   . LEU A 1 264 ? -5.94744  50.89076 -20.16191 1.000 21.48986 ? 265 LEU A O   1 
ATOM   1991 C CB  . LEU A 1 264 ? -4.37824  49.76847 -22.73934 1.000 20.14076 ? 265 LEU A CB  1 
ATOM   1992 C CG  . LEU A 1 264 ? -4.26466  49.93783 -24.26674 1.000 23.11654 ? 265 LEU A CG  1 
ATOM   1993 C CD1 . LEU A 1 264 ? -4.44410  48.59834 -25.01220 1.000 22.34512 ? 265 LEU A CD1 1 
ATOM   1994 C CD2 . LEU A 1 264 ? -5.24162  50.98730 -24.83206 1.000 21.61521 ? 265 LEU A CD2 1 
ATOM   1995 N N   . LEU A 1 265 ? -3.75013  50.76889 -19.64710 1.000 18.52881 ? 266 LEU A N   1 
ATOM   1996 C CA  . LEU A 1 265 ? -4.02440  50.68102 -18.21369 1.000 23.76209 ? 266 LEU A CA  1 
ATOM   1997 C C   . LEU A 1 265 ? -4.66830  51.96651 -17.70782 1.000 23.85392 ? 266 LEU A C   1 
ATOM   1998 O O   . LEU A 1 265 ? -5.61262  51.93434 -16.90160 1.000 22.89711 ? 266 LEU A O   1 
ATOM   1999 C CB  . LEU A 1 265 ? -2.73518  50.38221 -17.43844 1.000 21.63782 ? 266 LEU A CB  1 
ATOM   2000 C CG  . LEU A 1 265 ? -2.12911  49.00877 -17.73456 1.000 22.26100 ? 266 LEU A CG  1 
ATOM   2001 C CD1 . LEU A 1 265 ? -0.90315  48.79502 -16.87035 1.000 24.75482 ? 266 LEU A CD1 1 
ATOM   2002 C CD2 . LEU A 1 265 ? -3.17031  47.91326 -17.49307 1.000 21.85320 ? 266 LEU A CD2 1 
ATOM   2003 N N   . TYR A 1 266 ? -4.17745  53.10694 -18.18963 1.000 21.74814 ? 267 TYR A N   1 
ATOM   2004 C CA  . TYR A 1 266 ? -4.81742  54.38181 -17.89179 1.000 22.34390 ? 267 TYR A CA  1 
ATOM   2005 C C   . TYR A 1 266 ? -6.22637  54.44760 -18.47662 1.000 23.45234 ? 267 TYR A C   1 
ATOM   2006 O O   . TYR A 1 266 ? -7.14607  54.96455 -17.82905 1.000 22.35611 ? 267 TYR A O   1 
ATOM   2007 C CB  . TYR A 1 266 ? -3.95183  55.53726 -18.41758 1.000 23.24179 ? 267 TYR A CB  1 
ATOM   2008 C CG  . TYR A 1 266 ? -4.58432  56.90665 -18.19189 1.000 25.63049 ? 267 TYR A CG  1 
ATOM   2009 C CD1 . TYR A 1 266 ? -4.35995  57.62622 -17.01505 1.000 28.41200 ? 267 TYR A CD1 1 
ATOM   2010 C CD2 . TYR A 1 266 ? -5.42745  57.46144 -19.14398 1.000 25.55655 ? 267 TYR A CD2 1 
ATOM   2011 C CE1 . TYR A 1 266 ? -4.95976  58.89478 -16.81731 1.000 29.12329 ? 267 TYR A CE1 1 
ATOM   2012 C CE2 . TYR A 1 266 ? -6.01941  58.70345 -18.95548 1.000 28.40131 ? 267 TYR A CE2 1 
ATOM   2013 C CZ  . TYR A 1 266 ? -5.78442  59.40553 -17.79019 1.000 27.83234 ? 267 TYR A CZ  1 
ATOM   2014 O OH  . TYR A 1 266 ? -6.39640  60.62852 -17.63853 1.000 33.82750 ? 267 TYR A OH  1 
ATOM   2015 N N   . ALA A 1 267 ? -6.42080  53.93955 -19.70319 1.000 19.42311 ? 268 ALA A N   1 
ATOM   2016 C CA  . ALA A 1 267 ? -7.74511  54.00325 -20.32237 1.000 22.19812 ? 268 ALA A CA  1 
ATOM   2017 C C   . ALA A 1 267 ? -8.76003  53.18633 -19.54094 1.000 22.89590 ? 268 ALA A C   1 
ATOM   2018 O O   . ALA A 1 267 ? -9.91860  53.60071 -19.39682 1.000 22.39287 ? 268 ALA A O   1 
ATOM   2019 C CB  . ALA A 1 267 ? -7.69125  53.52059 -21.77531 1.000 21.55130 ? 268 ALA A CB  1 
ATOM   2020 N N   . ILE A 1 268 ? -8.34172  52.01454 -19.04326 1.000 21.50342 ? 269 ILE A N   1 
ATOM   2021 C CA  . ILE A 1 268 ? -9.22626  51.15171 -18.26490 1.000 23.22006 ? 269 ILE A CA  1 
ATOM   2022 C C   . ILE A 1 268 ? -9.73113  51.89809 -17.03284 1.000 23.68646 ? 269 ILE A C   1 
ATOM   2023 O O   . ILE A 1 268 ? -10.93169 51.89166 -16.71760 1.000 23.29242 ? 269 ILE A O   1 
ATOM   2024 C CB  . ILE A 1 268 ? -8.48945  49.85572 -17.87940 1.000 20.53968 ? 269 ILE A CB  1 
ATOM   2025 C CG1 . ILE A 1 268 ? -8.38151  48.92716 -19.09610 1.000 21.95792 ? 269 ILE A CG1 1 
ATOM   2026 C CG2 . ILE A 1 268 ? -9.16760  49.15318 -16.71484 1.000 22.47720 ? 269 ILE A CG2 1 
ATOM   2027 C CD1 . ILE A 1 268 ? -7.48196  47.72649 -18.84912 1.000 24.03709 ? 269 ILE A CD1 1 
ATOM   2028 N N   . GLN A 1 269 ? -8.81858  52.57422 -16.33817 1.000 22.72481 ? 270 GLN A N   1 
ATOM   2029 C CA  . GLN A 1 269 ? -9.18149  53.34501 -15.15002 1.000 22.88033 ? 270 GLN A CA  1 
ATOM   2030 C C   . GLN A 1 269 ? -10.25231 54.37454 -15.46646 1.000 27.79755 ? 270 GLN A C   1 
ATOM   2031 O O   . GLN A 1 269 ? -11.16323 54.59904 -14.66283 1.000 31.77880 ? 270 GLN A O   1 
ATOM   2032 C CB  . GLN A 1 269 ? -7.94384  54.03141 -14.57321 1.000 23.21618 ? 270 GLN A CB  1 
ATOM   2033 C CG  . GLN A 1 269 ? -6.98673  53.07385 -13.91047 1.000 25.44029 ? 270 GLN A CG  1 
ATOM   2034 C CD  . GLN A 1 269 ? -5.75036  53.77602 -13.41118 1.000 27.56303 ? 270 GLN A CD  1 
ATOM   2035 O OE1 . GLN A 1 269 ? -5.20190  54.66757 -14.07743 1.000 26.21585 ? 270 GLN A OE1 1 
ATOM   2036 N NE2 . GLN A 1 269 ? -5.30620  53.39184 -12.23095 1.000 24.39518 ? 270 GLN A NE2 1 
ATOM   2037 N N   . GLN A 1 270 ? -10.15936 55.01097 -16.63424 1.000 24.21082 ? 271 GLN A N   1 
ATOM   2038 C CA  . GLN A 1 270 ? -11.15612 55.99449 -17.03084 1.000 27.32160 ? 271 GLN A CA  1 
ATOM   2039 C C   . GLN A 1 270 ? -12.43805 55.32965 -17.52656 1.000 29.90595 ? 271 GLN A C   1 
ATOM   2040 O O   . GLN A 1 270 ? -13.54368 55.81274 -17.24276 1.000 27.34367 ? 271 GLN A O   1 
ATOM   2041 C CB  . GLN A 1 270 ? -10.58092 56.91397 -18.11377 1.000 28.47597 ? 271 GLN A CB  1 
ATOM   2042 C CG  . GLN A 1 270 ? -9.19441  57.43650 -17.80579 1.000 30.11706 ? 271 GLN A CG  1 
ATOM   2043 C CD  . GLN A 1 270 ? -9.12751  58.15742 -16.47478 1.000 35.15690 ? 271 GLN A CD  1 
ATOM   2044 O OE1 . GLN A 1 270 ? -10.02697 58.91382 -16.12659 1.000 36.71687 ? 271 GLN A OE1 1 
ATOM   2045 N NE2 . GLN A 1 270 ? -8.05182  57.93643 -15.73126 1.000 38.28515 ? 271 GLN A NE2 1 
ATOM   2046 N N   . LEU A 1 271 ? -12.31160 54.23400 -18.27960 1.000 26.97997 ? 272 LEU A N   1 
ATOM   2047 C CA  . LEU A 1 271 ? -13.49652 53.58702 -18.83773 1.000 24.54792 ? 272 LEU A CA  1 
ATOM   2048 C C   . LEU A 1 271 ? -14.30870 52.88925 -17.76071 1.000 29.16211 ? 272 LEU A C   1 
ATOM   2049 O O   . LEU A 1 271 ? -15.52942 52.75382 -17.89747 1.000 30.45153 ? 272 LEU A O   1 
ATOM   2050 C CB  . LEU A 1 271 ? -13.09166 52.59313 -19.92764 1.000 22.02621 ? 272 LEU A CB  1 
ATOM   2051 C CG  . LEU A 1 271 ? -12.43053 53.17869 -21.18525 1.000 25.66877 ? 272 LEU A CG  1 
ATOM   2052 C CD1 . LEU A 1 271 ? -11.80720 52.08180 -22.06004 1.000 24.01488 ? 272 LEU A CD1 1 
ATOM   2053 C CD2 . LEU A 1 271 ? -13.43041 54.00912 -21.98677 1.000 25.98472 ? 272 LEU A CD2 1 
ATOM   2054 N N   . TYR A 1 272 ? -13.65001 52.41944 -16.70009 1.000 24.19852 ? 273 TYR A N   1 
ATOM   2055 C CA  . TYR A 1 272 ? -14.37368 51.85736 -15.57111 1.000 31.19166 ? 273 TYR A CA  1 
ATOM   2056 C C   . TYR A 1 272 ? -15.34572 52.87482 -14.97132 1.000 34.33932 ? 273 TYR A C   1 
ATOM   2057 O O   . TYR A 1 272 ? -16.41080 52.49867 -14.47261 1.000 39.52476 ? 273 TYR A O   1 
ATOM   2058 C CB  . TYR A 1 272 ? -13.36974 51.38290 -14.52278 1.000 31.23649 ? 273 TYR A CB  1 
ATOM   2059 C CG  . TYR A 1 272 ? -13.98017 50.73067 -13.32066 1.000 31.95224 ? 273 TYR A CG  1 
ATOM   2060 C CD1 . TYR A 1 272 ? -14.80013 49.61379 -13.45326 1.000 36.65444 ? 273 TYR A CD1 1 
ATOM   2061 C CD2 . TYR A 1 272 ? -13.74912 51.23679 -12.04815 1.000 34.98406 ? 273 TYR A CD2 1 
ATOM   2062 C CE1 . TYR A 1 272 ? -15.36999 49.01120 -12.34323 1.000 42.46294 ? 273 TYR A CE1 1 
ATOM   2063 C CE2 . TYR A 1 272 ? -14.30692 50.64799 -10.93201 1.000 40.46334 ? 273 TYR A CE2 1 
ATOM   2064 C CZ  . TYR A 1 272 ? -15.11751 49.52894 -11.08378 1.000 41.87992 ? 273 TYR A CZ  1 
ATOM   2065 O OH  . TYR A 1 272 ? -15.68131 48.93854 -9.97812  1.000 40.92776 ? 273 TYR A OH  1 
ATOM   2066 N N   . THR A 1 273 ? -15.00418 54.16718 -15.02242 1.000 34.90811 ? 274 THR A N   1 
ATOM   2067 C CA  . THR A 1 273 ? -15.87342 55.18346 -14.42550 1.000 39.64631 ? 274 THR A CA  1 
ATOM   2068 C C   . THR A 1 273 ? -17.15318 55.37280 -15.23957 1.000 42.03097 ? 274 THR A C   1 
ATOM   2069 O O   . THR A 1 273 ? -18.14800 55.89488 -14.71986 1.000 46.86271 ? 274 THR A O   1 
ATOM   2070 C CB  . THR A 1 273 ? -15.12415 56.52041 -14.28131 1.000 38.28885 ? 274 THR A CB  1 
ATOM   2071 O OG1 . THR A 1 273 ? -14.92452 57.12422 -15.56405 1.000 41.70073 ? 274 THR A OG1 1 
ATOM   2072 C CG2 . THR A 1 273 ? -13.75852 56.32778 -13.62258 1.000 46.11675 ? 274 THR A CG2 1 
ATOM   2073 N N   . GLY A 1 274 ? -17.15407 54.94341 -16.49413 1.000 40.45313 ? 275 GLY A N   1 
ATOM   2074 C CA  . GLY A 1 274 ? -18.30745 54.99777 -17.37906 1.000 40.48731 ? 275 GLY A CA  1 
ATOM   2075 C C   . GLY A 1 274 ? -17.86057 55.33537 -18.79493 1.000 34.61190 ? 275 GLY A C   1 
ATOM   2076 O O   . GLY A 1 274 ? -16.91593 56.07817 -19.02765 1.000 40.12901 ? 275 GLY A O   1 
ATOM   2077 N N   . PHE A 1 275 ? -18.56856 54.77671 -19.77534 1.000 32.09641 ? 276 PHE A N   1 
ATOM   2078 C CA  . PHE A 1 275 ? -18.22308 55.04190 -21.17242 1.000 37.04654 ? 276 PHE A CA  1 
ATOM   2079 C C   . PHE A 1 275 ? -18.76382 56.36937 -21.68531 1.000 40.12464 ? 276 PHE A C   1 
ATOM   2080 O O   . PHE A 1 275 ? -18.60638 56.66072 -22.88106 1.000 37.22286 ? 276 PHE A O   1 
ATOM   2081 C CB  . PHE A 1 275 ? -18.75134 53.94178 -22.09364 1.000 35.76714 ? 276 PHE A CB  1 
ATOM   2082 C CG  . PHE A 1 275 ? -17.93618 52.67880 -22.08695 1.000 34.22105 ? 276 PHE A CG  1 
ATOM   2083 C CD1 . PHE A 1 275 ? -17.21308 52.30353 -20.96653 1.000 31.70663 ? 276 PHE A CD1 1 
ATOM   2084 C CD2 . PHE A 1 275 ? -17.92018 51.85412 -23.20161 1.000 27.89487 ? 276 PHE A CD2 1 
ATOM   2085 C CE1 . PHE A 1 275 ? -16.48277 51.12526 -20.96009 1.000 30.78788 ? 276 PHE A CE1 1 
ATOM   2086 C CE2 . PHE A 1 275 ? -17.18778 50.67131 -23.20141 1.000 30.93166 ? 276 PHE A CE2 1 
ATOM   2087 C CZ  . PHE A 1 275 ? -16.47163 50.31237 -22.07997 1.000 27.97634 ? 276 PHE A CZ  1 
ATOM   2088 N N   . GLN A 1 276 ? -19.39615 57.16891 -20.82705 1.000 47.69321 ? 277 GLN A N   1 
ATOM   2089 C CA  . GLN A 1 276 ? -20.19526 58.32184 -21.26040 1.000 44.12205 ? 277 GLN A CA  1 
ATOM   2090 C C   . GLN A 1 276 ? -21.17656 57.78273 -22.30406 1.000 45.53586 ? 277 GLN A C   1 
ATOM   2091 O O   . GLN A 1 276 ? -21.84712 56.77490 -22.04399 1.000 56.03630 ? 277 GLN A O   1 
ATOM   2092 C CB  . GLN A 1 276 ? -19.27824 59.44766 -21.71172 1.000 49.68811 ? 277 GLN A CB  1 
ATOM   2093 C CG  . GLN A 1 276 ? -18.17431 59.76549 -20.70516 1.000 53.65119 ? 277 GLN A CG  1 
ATOM   2094 C CD  . GLN A 1 276 ? -16.97110 60.43474 -21.34612 1.000 63.24479 ? 277 GLN A CD  1 
ATOM   2095 O OE1 . GLN A 1 276 ? -16.44126 59.96076 -22.35962 1.000 61.52093 ? 277 GLN A OE1 1 
ATOM   2096 N NE2 . GLN A 1 276 ? -16.53280 61.54441 -20.75937 1.000 63.12286 ? 277 GLN A NE2 1 
ATOM   2097 N N   . GLY A 1 277 ? -21.27128 58.36016 -23.48841 1.000 39.37131 ? 278 GLY A N   1 
ATOM   2098 C CA  . GLY A 1 277 ? -22.26779 57.82225 -24.39904 1.000 43.66573 ? 278 GLY A CA  1 
ATOM   2099 C C   . GLY A 1 277 ? -21.75804 56.85121 -25.44796 1.000 41.99003 ? 278 GLY A C   1 
ATOM   2100 O O   . GLY A 1 277 ? -22.45426 56.57518 -26.42986 1.000 39.17505 ? 278 GLY A O   1 
ATOM   2101 N N   . LYS A 1 278 ? -20.56902 56.29558 -25.25684 1.000 37.11924 ? 279 LYS A N   1 
ATOM   2102 C CA  . LYS A 1 278 ? -19.84595 55.72457 -26.38175 1.000 33.85979 ? 279 LYS A CA  1 
ATOM   2103 C C   . LYS A 1 278 ? -19.80499 54.19800 -26.31808 1.000 33.17992 ? 279 LYS A C   1 
ATOM   2104 O O   . LYS A 1 278 ? -20.14923 53.56314 -25.31575 1.000 31.63430 ? 279 LYS A O   1 
ATOM   2105 C CB  . LYS A 1 278 ? -18.44014 56.32777 -26.45243 1.000 31.76536 ? 279 LYS A CB  1 
ATOM   2106 C CG  . LYS A 1 278 ? -18.46538 57.85588 -26.58484 1.000 38.33073 ? 279 LYS A CG  1 
ATOM   2107 C CD  . LYS A 1 278 ? -17.13836 58.50716 -26.19912 1.000 37.88283 ? 279 LYS A CD  1 
ATOM   2108 C CE  . LYS A 1 278 ? -16.66266 59.45111 -27.31733 1.000 44.49954 ? 279 LYS A CE  1 
ATOM   2109 N NZ  . LYS A 1 278 ? -15.69817 60.51100 -26.85383 1.000 50.37915 ? 279 LYS A NZ  1 
ATOM   2110 N N   . GLN A 1 279 ? -19.41489 53.60957 -27.44041 1.000 29.69953 ? 280 GLN A N   1 
ATOM   2111 C CA  . GLN A 1 279 ? -19.32999 52.16483 -27.59528 1.000 31.30379 ? 280 GLN A CA  1 
ATOM   2112 C C   . GLN A 1 279 ? -17.89427 51.79668 -27.94908 1.000 31.28330 ? 280 GLN A C   1 
ATOM   2113 O O   . GLN A 1 279 ? -17.17070 52.59411 -28.55476 1.000 29.46717 ? 280 GLN A O   1 
ATOM   2114 C CB  . GLN A 1 279 ? -20.28296 51.65301 -28.69163 1.000 33.04122 ? 280 GLN A CB  1 
ATOM   2115 C CG  . GLN A 1 279 ? -19.84682 52.06114 -30.11267 1.000 39.93129 ? 280 GLN A CG  1 
ATOM   2116 C CD  . GLN A 1 279 ? -18.95747 51.01489 -30.81423 1.000 42.59178 ? 280 GLN A CD  1 
ATOM   2117 O OE1 . GLN A 1 279 ? -19.33944 49.85322 -30.95802 1.000 45.49799 ? 280 GLN A OE1 1 
ATOM   2118 N NE2 . GLN A 1 279 ? -17.75505 51.43124 -31.22926 1.000 42.40358 ? 280 GLN A NE2 1 
ATOM   2119 N N   . ILE A 1 280 ? -17.48954 50.58283 -27.57140 1.000 26.67361 ? 281 ILE A N   1 
ATOM   2120 C CA  . ILE A 1 280 ? -16.22965 49.97378 -28.00606 1.000 27.01530 ? 281 ILE A CA  1 
ATOM   2121 C C   . ILE A 1 280 ? -16.53889 48.57783 -28.52969 1.000 29.79569 ? 281 ILE A C   1 
ATOM   2122 O O   . ILE A 1 280 ? -17.02436 47.72684 -27.77251 1.000 25.58089 ? 281 ILE A O   1 
ATOM   2123 C CB  . ILE A 1 280 ? -15.19157 49.87607 -26.87364 1.000 24.92159 ? 281 ILE A CB  1 
ATOM   2124 C CG1 . ILE A 1 280 ? -14.82226 51.26308 -26.32967 1.000 23.42234 ? 281 ILE A CG1 1 
ATOM   2125 C CG2 . ILE A 1 280 ? -13.95200 49.10960 -27.37046 1.000 23.06814 ? 281 ILE A CG2 1 
ATOM   2126 C CD1 . ILE A 1 280 ? -13.99317 51.21237 -25.04367 1.000 23.67485 ? 281 ILE A CD1 1 
ATOM   2127 N N   . LEU A 1 281 ? -16.23683 48.33530 -29.81004 1.000 30.66076 ? 282 LEU A N   1 
ATOM   2128 C CA  . LEU A 1 281 ? -16.50140 47.04620 -30.46496 1.000 31.07153 ? 282 LEU A CA  1 
ATOM   2129 C C   . LEU A 1 281 ? -17.90507 46.53147 -30.14848 1.000 35.47204 ? 282 LEU A C   1 
ATOM   2130 O O   . LEU A 1 281 ? -18.09422 45.39712 -29.69882 1.000 32.38214 ? 282 LEU A O   1 
ATOM   2131 C CB  . LEU A 1 281 ? -15.45482 46.01011 -30.07275 1.000 30.32060 ? 282 LEU A CB  1 
ATOM   2132 C CG  . LEU A 1 281 ? -14.02814 46.30847 -30.51838 1.000 27.54609 ? 282 LEU A CG  1 
ATOM   2133 C CD1 . LEU A 1 281 ? -13.08589 45.29890 -29.87410 1.000 27.86506 ? 282 LEU A CD1 1 
ATOM   2134 C CD2 . LEU A 1 281 ? -13.91349 46.30635 -32.03147 1.000 32.28066 ? 282 LEU A CD2 1 
ATOM   2135 N N   . GLY A 1 282 ? -18.89623 47.39295 -30.36614 1.000 36.63813 ? 283 GLY A N   1 
ATOM   2136 C CA  . GLY A 1 282 ? -20.28044 46.99841 -30.18306 1.000 37.82705 ? 283 GLY A CA  1 
ATOM   2137 C C   . GLY A 1 282 ? -20.66534 46.71081 -28.75271 1.000 40.83430 ? 283 GLY A C   1 
ATOM   2138 O O   . GLY A 1 282 ? -21.57160 45.90738 -28.51431 1.000 55.68430 ? 283 GLY A O   1 
ATOM   2139 N N   . SER A 1 283 ? -19.99804 47.34028 -27.78916 1.000 37.79430 ? 284 SER A N   1 
ATOM   2140 C CA  . SER A 1 283 ? -20.25153 47.06828 -26.38355 1.000 33.76501 ? 284 SER A CA  1 
ATOM   2141 C C   . SER A 1 283 ? -20.21192 48.36920 -25.59386 1.000 32.55374 ? 284 SER A C   1 
ATOM   2142 O O   . SER A 1 283 ? -19.43857 49.27534 -25.90587 1.000 31.03752 ? 284 SER A O   1 
ATOM   2143 C CB  . SER A 1 283 ? -19.22962 46.07502 -25.81280 1.000 33.22300 ? 284 SER A CB  1 
ATOM   2144 O OG  . SER A 1 283 ? -19.43086 45.90847 -24.42338 1.000 31.98318 ? 284 SER A OG  1 
ATOM   2145 N N   . THR A 1 284 ? -21.05528 48.45633 -24.56583 1.000 28.69472 ? 285 THR A N   1 
ATOM   2146 C CA  . THR A 1 284 ? -21.07658 49.61725 -23.68691 1.000 32.37843 ? 285 THR A CA  1 
ATOM   2147 C C   . THR A 1 284 ? -20.45700 49.31476 -22.33013 1.000 28.54874 ? 285 THR A C   1 
ATOM   2148 O O   . THR A 1 284 ? -20.58746 50.11382 -21.39518 1.000 28.60827 ? 285 THR A O   1 
ATOM   2149 C CB  . THR A 1 284 ? -22.50908 50.13579 -23.53611 1.000 33.08175 ? 285 THR A CB  1 
ATOM   2150 O OG1 . THR A 1 284 ? -23.37527 49.07237 -23.11586 1.000 37.65430 ? 285 THR A OG1 1 
ATOM   2151 C CG2 . THR A 1 284 ? -22.98605 50.67150 -24.87074 1.000 35.72910 ? 285 THR A CG2 1 
ATOM   2152 N N   . MET A 1 285 ? -19.78004 48.17775 -22.20354 1.000 29.69122 ? 286 MET A N   1 
ATOM   2153 C CA  . MET A 1 285 ? -19.08074 47.82992 -20.97801 1.000 33.20059 ? 286 MET A CA  1 
ATOM   2154 C C   . MET A 1 285 ? -17.77817 47.13461 -21.34350 1.000 30.57172 ? 286 MET A C   1 
ATOM   2155 O O   . MET A 1 285 ? -17.58122 46.69297 -22.48267 1.000 29.22188 ? 286 MET A O   1 
ATOM   2156 C CB  . MET A 1 285 ? -19.94217 46.93240 -20.08211 1.000 35.14171 ? 286 MET A CB  1 
ATOM   2157 C CG  . MET A 1 285 ? -20.18331 45.55699 -20.68212 1.000 44.84430 ? 286 MET A CG  1 
ATOM   2158 S SD  . MET A 1 285 ? -21.46191 44.60342 -19.84868 1.000 71.00020 ? 286 MET A SD  1 
ATOM   2159 C CE  . MET A 1 285 ? -22.93160 45.08312 -20.76902 1.000 49.93629 ? 286 MET A CE  1 
ATOM   2160 N N   . LEU A 1 286 ? -16.88787 47.05007 -20.36314 1.000 26.83982 ? 287 LEU A N   1 
ATOM   2161 C CA  . LEU A 1 286 ? -15.61545 46.37472 -20.56877 1.000 29.24901 ? 287 LEU A CA  1 
ATOM   2162 C C   . LEU A 1 286 ? -15.82628 44.88149 -20.77206 1.000 28.74631 ? 287 LEU A C   1 
ATOM   2163 O O   . LEU A 1 286 ? -16.64599 44.25595 -20.09629 1.000 28.06140 ? 287 LEU A O   1 
ATOM   2164 C CB  . LEU A 1 286 ? -14.69565 46.60205 -19.37611 1.000 28.72405 ? 287 LEU A CB  1 
ATOM   2165 C CG  . LEU A 1 286 ? -14.30872 48.04152 -19.06181 1.000 25.86214 ? 287 LEU A CG  1 
ATOM   2166 C CD1 . LEU A 1 286 ? -13.48411 48.02862 -17.79203 1.000 32.28692 ? 287 LEU A CD1 1 
ATOM   2167 C CD2 . LEU A 1 286 ? -13.53127 48.64214 -20.20625 1.000 29.33988 ? 287 LEU A CD2 1 
ATOM   2168 N N   . GLU A 1 287 ? -15.06671 44.31414 -21.70178 1.000 28.30522 ? 288 GLU A N   1 
ATOM   2169 C CA  . GLU A 1 287 ? -15.14032 42.90308 -22.04882 1.000 23.71463 ? 288 GLU A CA  1 
ATOM   2170 C C   . GLU A 1 287 ? -13.84354 42.23518 -21.62207 1.000 20.88361 ? 288 GLU A C   1 
ATOM   2171 O O   . GLU A 1 287 ? -12.76125 42.68086 -22.01070 1.000 19.03053 ? 288 GLU A O   1 
ATOM   2172 C CB  . GLU A 1 287 ? -15.37290 42.74993 -23.55516 1.000 28.01341 ? 288 GLU A CB  1 
ATOM   2173 C CG  . GLU A 1 287 ? -15.29381 41.33018 -24.03118 1.000 36.60278 ? 288 GLU A CG  1 
ATOM   2174 C CD  . GLU A 1 287 ? -16.40947 40.49944 -23.44233 1.000 40.14251 ? 288 GLU A CD  1 
ATOM   2175 O OE1 . GLU A 1 287 ? -16.09507 39.46289 -22.80793 1.000 37.44417 ? 288 GLU A OE1 1 
ATOM   2176 O OE2 . GLU A 1 287 ? -17.58940 40.89073 -23.61391 1.000 44.56477 ? 288 GLU A OE2 1 
ATOM   2177 N N   . ASP A 1 288 ? -13.94459 41.17219 -20.81480 1.000 22.46743 ? 289 ASP A N   1 
ATOM   2178 C CA  . ASP A 1 288 ? -12.75181 40.51024 -20.30230 1.000 24.28254 ? 289 ASP A CA  1 
ATOM   2179 C C   . ASP A 1 288 ? -12.72179 39.01288 -20.61815 1.000 22.46237 ? 289 ASP A C   1 
ATOM   2180 O O   . ASP A 1 288 ? -11.98112 38.26942 -19.97273 1.000 21.88420 ? 289 ASP A O   1 
ATOM   2181 C CB  . ASP A 1 288 ? -12.62064 40.75043 -18.78917 1.000 22.17554 ? 289 ASP A CB  1 
ATOM   2182 C CG  . ASP A 1 288 ? -13.58523 39.89226 -17.95681 1.000 27.80766 ? 289 ASP A CG  1 
ATOM   2183 O OD1 . ASP A 1 288 ? -14.59519 39.37923 -18.49857 1.000 24.37039 ? 289 ASP A OD1 1 
ATOM   2184 O OD2 . ASP A 1 288 ? -13.31237 39.72424 -16.75055 1.000 24.65731 ? 289 ASP A OD2 1 
ATOM   2185 N N   . GLU A 1 289 ? -13.48764 38.54538 -21.59874 1.000 23.33826 ? 290 GLU A N   1 
ATOM   2186 C CA  . GLU A 1 289 ? -13.48407 37.12371 -21.93271 1.000 25.64700 ? 290 GLU A CA  1 
ATOM   2187 C C   . GLU A 1 289 ? -12.75159 36.82117 -23.24355 1.000 27.54740 ? 290 GLU A C   1 
ATOM   2188 O O   . GLU A 1 289 ? -12.84651 35.69843 -23.75081 1.000 25.65891 ? 290 GLU A O   1 
ATOM   2189 C CB  . GLU A 1 289 ? -14.92186 36.57911 -21.96421 1.000 29.96409 ? 290 GLU A CB  1 
ATOM   2190 C CG  . GLU A 1 289 ? -15.70525 36.71075 -20.60011 1.000 34.98869 ? 290 GLU A CG  1 
ATOM   2191 C CD  . GLU A 1 289 ? -16.21969 35.36317 -20.00031 1.000 40.63075 ? 290 GLU A CD  1 
ATOM   2192 O OE1 . GLU A 1 289 ? -16.52450 35.32063 -18.76828 1.000 31.61647 ? 290 GLU A OE1 1 
ATOM   2193 O OE2 . GLU A 1 289 ? -16.30287 34.34414 -20.74216 1.000 37.93825 ? 290 GLU A OE2 1 
ATOM   2194 N N   . PHE A 1 290 ? -12.00975 37.78209 -23.79256 1.000 21.63730 ? 291 PHE A N   1 
ATOM   2195 C CA  . PHE A 1 290 ? -11.10889 37.55079 -24.91542 1.000 22.25225 ? 291 PHE A CA  1 
ATOM   2196 C C   . PHE A 1 290 ? -9.67075  37.65672 -24.43015 1.000 24.00699 ? 291 PHE A C   1 
ATOM   2197 O O   . PHE A 1 290 ? -9.27607  38.68504 -23.86506 1.000 21.75352 ? 291 PHE A O   1 
ATOM   2198 C CB  . PHE A 1 290 ? -11.35030 38.55867 -26.04045 1.000 22.66909 ? 291 PHE A CB  1 
ATOM   2199 C CG  . PHE A 1 290 ? -12.66613 38.37816 -26.71840 1.000 26.71775 ? 291 PHE A CG  1 
ATOM   2200 C CD1 . PHE A 1 290 ? -12.86396 37.32108 -27.59499 1.000 26.72888 ? 291 PHE A CD1 1 
ATOM   2201 C CD2 . PHE A 1 290 ? -13.71179 39.24528 -26.46772 1.000 29.50673 ? 291 PHE A CD2 1 
ATOM   2202 C CE1 . PHE A 1 290 ? -14.08462 37.13757 -28.21684 1.000 28.25599 ? 291 PHE A CE1 1 
ATOM   2203 C CE2 . PHE A 1 290 ? -14.93958 39.06964 -27.08597 1.000 32.59510 ? 291 PHE A CE2 1 
ATOM   2204 C CZ  . PHE A 1 290 ? -15.12294 38.02145 -27.96760 1.000 29.81202 ? 291 PHE A CZ  1 
ATOM   2205 N N   . THR A 1 291 ? -8.88352  36.60629 -24.67023 1.000 20.82229 ? 292 THR A N   1 
ATOM   2206 C CA  . THR A 1 291 ? -7.50104  36.58037 -24.20918 1.000 21.42859 ? 292 THR A CA  1 
ATOM   2207 C C   . THR A 1 291 ? -6.57368  37.25218 -25.21784 1.000 18.97474 ? 292 THR A C   1 
ATOM   2208 O O   . THR A 1 291 ? -6.94611  37.47291 -26.37011 1.000 20.09404 ? 292 THR A O   1 
ATOM   2209 C CB  . THR A 1 291 ? -7.05921  35.14038 -23.97399 1.000 21.34050 ? 292 THR A CB  1 
ATOM   2210 O OG1 . THR A 1 291 ? -6.93544  34.47810 -25.23785 1.000 21.77879 ? 292 THR A OG1 1 
ATOM   2211 C CG2 . THR A 1 291 ? -8.10163  34.40436 -23.11719 1.000 22.02058 ? 292 THR A CG2 1 
ATOM   2212 N N   . PRO A 1 292 ? -5.35394  37.60691 -24.80642 1.000 19.45793 ? 293 PRO A N   1 
ATOM   2213 C CA  . PRO A 1 292 ? -4.39498  38.13149 -25.79454 1.000 21.37221 ? 293 PRO A CA  1 
ATOM   2214 C C   . PRO A 1 292 ? -4.13106  37.14237 -26.92007 1.000 18.94249 ? 293 PRO A C   1 
ATOM   2215 O O   . PRO A 1 292 ? -4.03145  37.54660 -28.07748 1.000 20.92394 ? 293 PRO A O   1 
ATOM   2216 C CB  . PRO A 1 292 ? -3.14352  38.41320 -24.94384 1.000 21.64232 ? 293 PRO A CB  1 
ATOM   2217 C CG  . PRO A 1 292 ? -3.69563  38.63660 -23.54401 1.000 23.14468 ? 293 PRO A CG  1 
ATOM   2218 C CD  . PRO A 1 292 ? -4.82624  37.66515 -23.42878 1.000 20.05272 ? 293 PRO A CD  1 
ATOM   2219 N N   . GLU A 1 293 ? -4.06449  35.84471 -26.60501 1.000 21.93364 ? 294 GLU A N   1 
ATOM   2220 C CA  . GLU A 1 293 ? -3.90187  34.81792 -27.64084 1.000 20.65824 ? 294 GLU A CA  1 
ATOM   2221 C C   . GLU A 1 293 ? -5.07375  34.80987 -28.61653 1.000 24.23101 ? 294 GLU A C   1 
ATOM   2222 O O   . GLU A 1 293 ? -4.86548  34.74311 -29.83515 1.000 24.90384 ? 294 GLU A O   1 
ATOM   2223 C CB  . GLU A 1 293 ? -3.72685  33.44684 -26.97788 1.000 22.12580 ? 294 GLU A CB  1 
ATOM   2224 C CG  . GLU A 1 293 ? -2.43615  33.32204 -26.16466 1.000 25.54257 ? 294 GLU A CG  1 
ATOM   2225 C CD  . GLU A 1 293 ? -2.55748  33.83263 -24.71184 1.000 31.74067 ? 294 GLU A CD  1 
ATOM   2226 O OE1 . GLU A 1 293 ? -3.65962  34.25401 -24.28708 1.000 28.27520 ? 294 GLU A OE1 1 
ATOM   2227 O OE2 . GLU A 1 293 ? -1.53261  33.80634 -23.98507 1.000 32.73977 ? 294 GLU A OE2 1 
ATOM   2228 N N   . ASP A 1 294 ? -6.31240  34.90056 -28.10506 1.000 22.43195 ? 295 ASP A N   1 
ATOM   2229 C CA  . ASP A 1 294 ? -7.49630  35.04657 -28.96298 1.000 21.66616 ? 295 ASP A CA  1 
ATOM   2230 C C   . ASP A 1 294 ? -7.36519  36.19278 -29.95708 1.000 26.36968 ? 295 ASP A C   1 
ATOM   2231 O O   . ASP A 1 294 ? -7.70875  36.05185 -31.14102 1.000 23.05296 ? 295 ASP A O   1 
ATOM   2232 C CB  . ASP A 1 294 ? -8.74549  35.32592 -28.12522 1.000 24.38191 ? 295 ASP A CB  1 
ATOM   2233 C CG  . ASP A 1 294 ? -9.25625  34.12380 -27.41075 1.000 31.36135 ? 295 ASP A CG  1 
ATOM   2234 O OD1 . ASP A 1 294 ? -8.94060  32.99561 -27.86354 1.000 34.43350 ? 295 ASP A OD1 1 
ATOM   2235 O OD2 . ASP A 1 294 ? -9.98396  34.32274 -26.39062 1.000 30.94449 ? 295 ASP A OD2 1 
ATOM   2236 N N   . VAL A 1 295 ? -6.96746  37.37241 -29.46724 1.000 21.34899 ? 296 VAL A N   1 
ATOM   2237 C CA  . VAL A 1 295 ? -6.91484  38.53917 -30.33906 1.000 22.94810 ? 296 VAL A CA  1 
ATOM   2238 C C   . VAL A 1 295 ? -5.82337  38.36170 -31.38690 1.000 24.19935 ? 296 VAL A C   1 
ATOM   2239 O O   . VAL A 1 295 ? -6.01002  38.68475 -32.56677 1.000 24.94934 ? 296 VAL A O   1 
ATOM   2240 C CB  . VAL A 1 295 ? -6.71062  39.82054 -29.50141 1.000 21.23337 ? 296 VAL A CB  1 
ATOM   2241 C CG1 . VAL A 1 295 ? -6.50275  41.03213 -30.41013 1.000 22.62736 ? 296 VAL A CG1 1 
ATOM   2242 C CG2 . VAL A 1 295 ? -7.91834  40.04996 -28.62788 1.000 20.99822 ? 296 VAL A CG2 1 
ATOM   2243 N N   . ASN A 1 296 ? -4.66641  37.86196 -30.96481 1.000 22.09550 ? 297 ASN A N   1 
ATOM   2244 C CA  . ASN A 1 296 ? -3.57942  37.59857 -31.89798 1.000 27.50961 ? 297 ASN A CA  1 
ATOM   2245 C C   . ASN A 1 296 ? -4.00407  36.59475 -32.96316 1.000 28.99105 ? 297 ASN A C   1 
ATOM   2246 O O   . ASN A 1 296 ? -3.68673  36.76313 -34.14338 1.000 28.57652 ? 297 ASN A O   1 
ATOM   2247 C CB  . ASN A 1 296 ? -2.35595  37.08869 -31.13130 1.000 23.48690 ? 297 ASN A CB  1 
ATOM   2248 C CG  . ASN A 1 296 ? -1.43888  38.22444 -30.65828 1.000 27.43758 ? 297 ASN A CG  1 
ATOM   2249 O OD1 . ASN A 1 296 ? -0.70744  38.82631 -31.45624 1.000 34.08631 ? 297 ASN A OD1 1 
ATOM   2250 N ND2 . ASN A 1 296 ? -1.48231  38.52424 -29.36720 1.000 22.81139 ? 297 ASN A ND2 1 
ATOM   2251 N N   . MET A 1 297 ? -4.71690  35.53839 -32.56180 1.000 26.21054 ? 298 MET A N   1 
ATOM   2252 C CA  . MET A 1 297 ? -5.13281  34.50424 -33.51365 1.000 28.32312 ? 298 MET A CA  1 
ATOM   2253 C C   . MET A 1 297 ? -6.18394  35.03049 -34.47682 1.000 30.62979 ? 298 MET A C   1 
ATOM   2254 O O   . MET A 1 297 ? -6.10581  34.79565 -35.68863 1.000 28.70494 ? 298 MET A O   1 
ATOM   2255 C CB  . MET A 1 297 ? -5.70103  33.28835 -32.78129 1.000 28.45116 ? 298 MET A CB  1 
ATOM   2256 C CG  . MET A 1 297 ? -4.72964  32.47839 -31.95957 1.000 37.63814 ? 298 MET A CG  1 
ATOM   2257 S SD  . MET A 1 297 ? -5.50216  30.90925 -31.48140 1.000 55.81455 ? 298 MET A SD  1 
ATOM   2258 C CE  . MET A 1 297 ? -6.73702  31.47355 -30.30379 1.000 49.08053 ? 298 MET A CE  1 
ATOM   2259 N N   . GLN A 1 298 ? -7.17916  35.74075 -33.94824 1.000 27.93058 ? 299 GLN A N   1 
ATOM   2260 C CA  . GLN A 1 298 ? -8.35940  36.08629 -34.72779 1.000 31.88276 ? 299 GLN A CA  1 
ATOM   2261 C C   . GLN A 1 298 ? -8.13985  37.29808 -35.61369 1.000 32.71996 ? 299 GLN A C   1 
ATOM   2262 O O   . GLN A 1 298 ? -8.70982  37.36739 -36.70588 1.000 32.45485 ? 299 GLN A O   1 
ATOM   2263 C CB  . GLN A 1 298 ? -9.54832  36.33205 -33.79690 1.000 28.16961 ? 299 GLN A CB  1 
ATOM   2264 C CG  . GLN A 1 298 ? -10.09847 35.04280 -33.17665 1.000 28.31517 ? 299 GLN A CG  1 
ATOM   2265 C CD  . GLN A 1 298 ? -11.51222 35.21624 -32.65201 1.000 32.30548 ? 299 GLN A CD  1 
ATOM   2266 O OE1 . GLN A 1 298 ? -12.34740 35.86128 -33.28812 1.000 32.58570 ? 299 GLN A OE1 1 
ATOM   2267 N NE2 . GLN A 1 298 ? -11.78168 34.65778 -31.48637 1.000 26.47783 ? 299 GLN A NE2 1 
ATOM   2268 N N   . ILE A 1 299 ? -7.32339  38.25100 -35.18280 1.000 30.12901 ? 300 ILE A N   1 
ATOM   2269 C CA  . ILE A 1 299 ? -7.14662  39.47586 -35.93617 1.000 36.19342 ? 300 ILE A CA  1 
ATOM   2270 C C   . ILE A 1 299 ? -5.80121  39.54355 -36.65848 1.000 40.67976 ? 300 ILE A C   1 
ATOM   2271 O O   . ILE A 1 299 ? -5.72346  40.14225 -37.73739 1.000 44.87926 ? 300 ILE A O   1 
ATOM   2272 C CB  . ILE A 1 299 ? -7.35260  40.69455 -35.01550 1.000 37.03862 ? 300 ILE A CB  1 
ATOM   2273 C CG1 . ILE A 1 299 ? -8.82642  40.77583 -34.65478 1.000 34.39188 ? 300 ILE A CG1 1 
ATOM   2274 C CG2 . ILE A 1 299 ? -6.92888  41.99035 -35.68990 1.000 40.19366 ? 300 ILE A CG2 1 
ATOM   2275 C CD1 . ILE A 1 299 ? -9.06416  41.22554 -33.27235 1.000 37.11863 ? 300 ILE A CD1 1 
ATOM   2276 N N   . MET A 1 300 ? -4.75028  38.92686 -36.12564 1.000 38.95764 ? 301 MET A N   1 
ATOM   2277 C CA  . MET A 1 300 ? -3.47027  38.89975 -36.84367 1.000 46.44994 ? 301 MET A CA  1 
ATOM   2278 C C   . MET A 1 300 ? -3.31840  37.63246 -37.69675 1.000 44.89037 ? 301 MET A C   1 
ATOM   2279 O O   . MET A 1 300 ? -3.93426  36.59683 -37.42111 1.000 44.31445 ? 301 MET A O   1 
ATOM   2280 C CB  . MET A 1 300 ? -2.30671  39.00497 -35.86282 1.000 44.43064 ? 301 MET A CB  1 
ATOM   2281 C CG  . MET A 1 300 ? -2.49694  40.06219 -34.78807 1.000 43.45635 ? 301 MET A CG  1 
ATOM   2282 S SD  . MET A 1 300 ? -2.41811  41.72531 -35.47054 1.000 55.85460 ? 301 MET A SD  1 
ATOM   2283 C CE  . MET A 1 300 ? -1.27765  42.46702 -34.29431 1.000 47.52006 ? 301 MET A CE  1 
ATOM   2284 N N   . GLY B 1 1   ? -28.04201 36.58333 -19.14006 1.000 42.34854 ? 2   GLY B N   1 
ATOM   2285 C CA  . GLY B 1 1   ? -26.97922 35.59812 -19.06759 1.000 40.68115 ? 2   GLY B CA  1 
ATOM   2286 C C   . GLY B 1 1   ? -26.89966 34.68110 -20.28233 1.000 43.23964 ? 2   GLY B C   1 
ATOM   2287 O O   . GLY B 1 1   ? -26.61763 33.48465 -20.14806 1.000 42.38843 ? 2   GLY B O   1 
ATOM   2288 N N   . LEU B 1 2   ? -27.14913 35.23505 -21.46942 1.000 38.98454 ? 3   LEU B N   1 
ATOM   2289 C CA  . LEU B 1 2   ? -27.10259 34.45218 -22.70433 1.000 33.15834 ? 3   LEU B CA  1 
ATOM   2290 C C   . LEU B 1 2   ? -25.66033 34.13364 -23.09377 1.000 30.99155 ? 3   LEU B C   1 
ATOM   2291 O O   . LEU B 1 2   ? -24.76986 34.96904 -22.94182 1.000 33.32882 ? 3   LEU B O   1 
ATOM   2292 C CB  . LEU B 1 2   ? -27.75385 35.23461 -23.84214 1.000 33.10103 ? 3   LEU B CB  1 
ATOM   2293 C CG  . LEU B 1 2   ? -29.23268 35.12690 -24.24514 1.000 37.72619 ? 3   LEU B CG  1 
ATOM   2294 C CD1 . LEU B 1 2   ? -30.03082 34.15541 -23.38982 1.000 29.53505 ? 3   LEU B CD1 1 
ATOM   2295 C CD2 . LEU B 1 2   ? -29.87958 36.51748 -24.28449 1.000 33.25869 ? 3   LEU B CD2 1 
ATOM   2296 N N   . VAL B 1 3   ? -25.43157 32.94536 -23.65412 1.000 29.95647 ? 4   VAL B N   1 
ATOM   2297 C CA  . VAL B 1 3   ? -24.10874 32.60736 -24.16998 1.000 28.45165 ? 4   VAL B CA  1 
ATOM   2298 C C   . VAL B 1 3   ? -24.21593 32.21479 -25.64288 1.000 27.53005 ? 4   VAL B C   1 
ATOM   2299 O O   . VAL B 1 3   ? -25.23883 31.70533 -26.10646 1.000 25.60768 ? 4   VAL B O   1 
ATOM   2300 C CB  . VAL B 1 3   ? -23.42697 31.49369 -23.33512 1.000 32.96457 ? 4   VAL B CB  1 
ATOM   2301 C CG1 . VAL B 1 3   ? -23.61370 31.74524 -21.82035 1.000 32.65833 ? 4   VAL B CG1 1 
ATOM   2302 C CG2 . VAL B 1 3   ? -23.93590 30.14772 -23.70488 1.000 33.58899 ? 4   VAL B CG2 1 
ATOM   2303 N N   . LYS B 1 4   ? -23.15179 32.48415 -26.38775 1.000 26.79342 ? 5   LYS B N   1 
ATOM   2304 C CA  . LYS B 1 4   ? -23.05574 32.03722 -27.77682 1.000 28.97973 ? 5   LYS B CA  1 
ATOM   2305 C C   . LYS B 1 4   ? -22.81195 30.53163 -27.79732 1.000 27.79011 ? 5   LYS B C   1 
ATOM   2306 O O   . LYS B 1 4   ? -21.74389 30.06897 -27.39471 1.000 30.26127 ? 5   LYS B O   1 
ATOM   2307 C CB  . LYS B 1 4   ? -21.92345 32.78447 -28.48035 1.000 29.59881 ? 5   LYS B CB  1 
ATOM   2308 C CG  . LYS B 1 4   ? -22.36807 33.84829 -29.49593 1.000 34.19987 ? 5   LYS B CG  1 
ATOM   2309 C CD  . LYS B 1 4   ? -23.33099 34.83802 -28.91242 1.000 36.03075 ? 5   LYS B CD  1 
ATOM   2310 C CE  . LYS B 1 4   ? -24.00273 35.66786 -29.99449 1.000 35.02562 ? 5   LYS B CE  1 
ATOM   2311 N NZ  . LYS B 1 4   ? -23.06209 36.56984 -30.73016 1.000 34.42159 ? 5   LYS B NZ  1 
ATOM   2312 N N   . MET B 1 5   ? -23.78531 29.75620 -28.25252 1.000 25.37991 ? 6   MET B N   1 
ATOM   2313 C CA  . MET B 1 5   ? -23.66476 28.29895 -28.27598 1.000 26.53201 ? 6   MET B CA  1 
ATOM   2314 C C   . MET B 1 5   ? -23.69173 27.78970 -29.71509 1.000 28.45007 ? 6   MET B C   1 
ATOM   2315 O O   . MET B 1 5   ? -24.50373 28.24021 -30.53626 1.000 27.92622 ? 6   MET B O   1 
ATOM   2316 C CB  . MET B 1 5   ? -24.78321 27.65143 -27.47184 1.000 27.79912 ? 6   MET B CB  1 
ATOM   2317 C CG  . MET B 1 5   ? -24.53012 26.19759 -27.05572 1.000 32.52814 ? 6   MET B CG  1 
ATOM   2318 S SD  . MET B 1 5   ? -25.61423 25.73416 -25.67769 1.000 48.29974 ? 6   MET B SD  1 
ATOM   2319 C CE  . MET B 1 5   ? -26.00775 27.36018 -25.02678 1.000 33.63623 ? 6   MET B CE  1 
ATOM   2320 N N   . SER B 1 6   ? -22.80397 26.85273 -30.01666 1.000 22.45459 ? 7   SER B N   1 
ATOM   2321 C CA  . SER B 1 6   ? -22.75858 26.20034 -31.31593 1.000 22.60270 ? 7   SER B CA  1 
ATOM   2322 C C   . SER B 1 6   ? -23.15340 24.73396 -31.18778 1.000 20.92100 ? 7   SER B C   1 
ATOM   2323 O O   . SER B 1 6   ? -23.06283 24.14108 -30.11733 1.000 22.88743 ? 7   SER B O   1 
ATOM   2324 C CB  . SER B 1 6   ? -21.35695 26.29412 -31.92138 1.000 23.36245 ? 7   SER B CB  1 
ATOM   2325 O OG  . SER B 1 6   ? -21.02089 27.62839 -32.22090 1.000 31.04889 ? 7   SER B OG  1 
ATOM   2326 N N   . HIS B 1 7   ? -23.57517 24.14233 -32.29666 1.000 20.02118 ? 8   HIS B N   1 
ATOM   2327 C CA  . HIS B 1 7   ? -23.79866 22.70766 -32.30138 1.000 22.59523 ? 8   HIS B CA  1 
ATOM   2328 C C   . HIS B 1 7   ? -22.45657 21.99015 -32.20222 1.000 23.20308 ? 8   HIS B C   1 
ATOM   2329 O O   . HIS B 1 7   ? -21.44049 22.50112 -32.67753 1.000 20.00981 ? 8   HIS B O   1 
ATOM   2330 C CB  . HIS B 1 7   ? -24.51040 22.26119 -33.57850 1.000 25.57413 ? 8   HIS B CB  1 
ATOM   2331 C CG  . HIS B 1 7   ? -25.91549 22.76074 -33.69553 1.000 26.11450 ? 8   HIS B CG  1 
ATOM   2332 N ND1 . HIS B 1 7   ? -26.94394 22.27986 -32.91142 1.000 29.67363 ? 8   HIS B ND1 1 
ATOM   2333 C CD2 . HIS B 1 7   ? -26.46663 23.69305 -34.51073 1.000 29.05166 ? 8   HIS B CD2 1 
ATOM   2334 C CE1 . HIS B 1 7   ? -28.06533 22.90676 -33.22682 1.000 31.78778 ? 8   HIS B CE1 1 
ATOM   2335 N NE2 . HIS B 1 7   ? -27.80396 23.76930 -34.19327 1.000 30.62755 ? 8   HIS B NE2 1 
ATOM   2336 N N   . PRO B 1 8   ? -22.41985 20.81356 -31.57984 1.000 22.86192 ? 9   PRO B N   1 
ATOM   2337 C CA  . PRO B 1 8   ? -21.22368 19.96222 -31.70333 1.000 22.72797 ? 9   PRO B CA  1 
ATOM   2338 C C   . PRO B 1 8   ? -20.85952 19.79244 -33.17724 1.000 24.58285 ? 9   PRO B C   1 
ATOM   2339 O O   . PRO B 1 8   ? -21.72985 19.60834 -34.02351 1.000 24.50491 ? 9   PRO B O   1 
ATOM   2340 C CB  . PRO B 1 8   ? -21.66164 18.63730 -31.06863 1.000 22.51940 ? 9   PRO B CB  1 
ATOM   2341 C CG  . PRO B 1 8   ? -22.81594 19.01732 -30.13732 1.000 22.56209 ? 9   PRO B CG  1 
ATOM   2342 C CD  . PRO B 1 8   ? -23.52737 20.14036 -30.87157 1.000 20.48001 ? 9   PRO B CD  1 
ATOM   2343 N N   . SER B 1 9   ? -19.57029 19.89980 -33.50518 1.000 22.96302 ? 10  SER B N   1 
ATOM   2344 C CA  . SER B 1 9   ? -19.17049 19.91245 -34.91057 1.000 20.81808 ? 10  SER B CA  1 
ATOM   2345 C C   . SER B 1 9   ? -18.69973 18.55726 -35.44332 1.000 22.77784 ? 10  SER B C   1 
ATOM   2346 O O   . SER B 1 9   ? -18.37691 18.46290 -36.63603 1.000 23.16616 ? 10  SER B O   1 
ATOM   2347 C CB  . SER B 1 9   ? -18.06090 20.94594 -35.13782 1.000 23.95674 ? 10  SER B CB  1 
ATOM   2348 O OG  . SER B 1 9   ? -16.93834 20.64097 -34.31805 1.000 22.20182 ? 10  SER B OG  1 
ATOM   2349 N N   . GLY B 1 10  ? -18.62782 17.51926 -34.60309 1.000 20.65366 ? 11  GLY B N   1 
ATOM   2350 C CA  . GLY B 1 10  ? -17.99633 16.27267 -35.02528 1.000 21.66502 ? 11  GLY B CA  1 
ATOM   2351 C C   . GLY B 1 10  ? -18.56774 15.69966 -36.31080 1.000 23.07467 ? 11  GLY B C   1 
ATOM   2352 O O   . GLY B 1 10  ? -17.82105 15.27226 -37.19675 1.000 20.40331 ? 11  GLY B O   1 
ATOM   2353 N N   . ASP B 1 11  ? -19.89999 15.69197 -36.43394 1.000 22.38786 ? 12  ASP B N   1 
ATOM   2354 C CA  . ASP B 1 11  ? -20.54601 15.15083 -37.63191 1.000 25.67721 ? 12  ASP B CA  1 
ATOM   2355 C C   . ASP B 1 11  ? -20.06745 15.85273 -38.89654 1.000 24.58406 ? 12  ASP B C   1 
ATOM   2356 O O   . ASP B 1 11  ? -19.85957 15.20968 -39.93688 1.000 23.71508 ? 12  ASP B O   1 
ATOM   2357 C CB  . ASP B 1 11  ? -22.06529 15.29155 -37.51962 1.000 30.83991 ? 12  ASP B CB  1 
ATOM   2358 C CG  . ASP B 1 11  ? -22.67473 14.32403 -36.53188 1.000 43.53945 ? 12  ASP B CG  1 
ATOM   2359 O OD1 . ASP B 1 11  ? -21.96414 13.40088 -36.05710 1.000 41.80869 ? 12  ASP B OD1 1 
ATOM   2360 O OD2 . ASP B 1 11  ? -23.87533 14.50255 -36.22088 1.000 49.06510 ? 12  ASP B OD2 1 
ATOM   2361 N N   . VAL B 1 12  ? -19.90831 17.17755 -38.82933 1.000 19.51228 ? 13  VAL B N   1 
ATOM   2362 C CA  . VAL B 1 12  ? -19.50401 17.96034 -39.99185 1.000 21.89555 ? 13  VAL B CA  1 
ATOM   2363 C C   . VAL B 1 12  ? -18.00857 17.83795 -40.23913 1.000 23.03545 ? 13  VAL B C   1 
ATOM   2364 O O   . VAL B 1 12  ? -17.56241 17.78020 -41.39171 1.000 19.29920 ? 13  VAL B O   1 
ATOM   2365 C CB  . VAL B 1 12  ? -19.94094 19.42922 -39.81229 1.000 19.30492 ? 13  VAL B CB  1 
ATOM   2366 C CG1 . VAL B 1 12  ? -19.47443 20.28783 -40.98617 1.000 20.88379 ? 13  VAL B CG1 1 
ATOM   2367 C CG2 . VAL B 1 12  ? -21.45403 19.50385 -39.70057 1.000 23.45063 ? 13  VAL B CG2 1 
ATOM   2368 N N   . GLU B 1 13  ? -17.21129 17.76217 -39.16903 1.000 20.43543 ? 14  GLU B N   1 
ATOM   2369 C CA  . GLU B 1 13  ? -15.77455 17.58900 -39.33408 1.000 21.67217 ? 14  GLU B CA  1 
ATOM   2370 C C   . GLU B 1 13  ? -15.45968 16.38208 -40.20715 1.000 21.94619 ? 14  GLU B C   1 
ATOM   2371 O O   . GLU B 1 13  ? -14.51777 16.41076 -41.00789 1.000 22.57436 ? 14  GLU B O   1 
ATOM   2372 C CB  . GLU B 1 13  ? -15.09768 17.41715 -37.97144 1.000 21.23651 ? 14  GLU B CB  1 
ATOM   2373 C CG  . GLU B 1 13  ? -15.07692 18.64306 -37.09530 1.000 20.09296 ? 14  GLU B CG  1 
ATOM   2374 C CD  . GLU B 1 13  ? -14.62535 18.30965 -35.68799 1.000 22.01219 ? 14  GLU B CD  1 
ATOM   2375 O OE1 . GLU B 1 13  ? -13.55496 17.69764 -35.56105 1.000 20.84911 ? 14  GLU B OE1 1 
ATOM   2376 O OE2 . GLU B 1 13  ? -15.33405 18.66006 -34.71945 1.000 23.59266 ? 14  GLU B OE2 1 
ATOM   2377 N N   . ALA B 1 14  ? -16.22317 15.30139 -40.04280 1.000 21.14357 ? 15  ALA B N   1 
ATOM   2378 C CA  . ALA B 1 14  ? -15.96816 14.07934 -40.78935 1.000 25.75551 ? 15  ALA B CA  1 
ATOM   2379 C C   . ALA B 1 14  ? -16.27400 14.22576 -42.27808 1.000 25.89256 ? 15  ALA B C   1 
ATOM   2380 O O   . ALA B 1 14  ? -15.91693 13.33000 -43.05832 1.000 27.80705 ? 15  ALA B O   1 
ATOM   2381 C CB  . ALA B 1 14  ? -16.78270 12.92549 -40.17789 1.000 23.86575 ? 15  ALA B CB  1 
ATOM   2382 N N   . CYS B 1 15  ? -16.88688 15.33428 -42.69582 1.000 22.20008 ? 16  CYS B N   1 
ATOM   2383 C CA  . CYS B 1 15  ? -17.18633 15.57627 -44.09951 1.000 24.84423 ? 16  CYS B CA  1 
ATOM   2384 C C   . CYS B 1 15  ? -16.25813 16.58486 -44.76188 1.000 21.63050 ? 16  CYS B C   1 
ATOM   2385 O O   . CYS B 1 15  ? -16.40475 16.83028 -45.96123 1.000 22.07084 ? 16  CYS B O   1 
ATOM   2386 C CB  . CYS B 1 15  ? -18.62698 16.07006 -44.25990 1.000 23.84426 ? 16  CYS B CB  1 
ATOM   2387 S SG  . CYS B 1 15  ? -19.87727 15.04321 -43.50494 1.000 25.69712 ? 16  CYS B SG  1 
ATOM   2388 N N   . MET B 1 16  ? -15.33260 17.20434 -44.03010 1.000 22.33867 ? 17  MET B N   1 
ATOM   2389 C CA  . MET B 1 16  ? -14.51946 18.25346 -44.63990 1.000 21.48804 ? 17  MET B CA  1 
ATOM   2390 C C   . MET B 1 16  ? -13.38153 17.65628 -45.46156 1.000 24.57649 ? 17  MET B C   1 
ATOM   2391 O O   . MET B 1 16  ? -12.74791 16.67810 -45.05382 1.000 22.29485 ? 17  MET B O   1 
ATOM   2392 C CB  . MET B 1 16  ? -13.95662 19.19889 -43.57951 1.000 23.22508 ? 17  MET B CB  1 
ATOM   2393 C CG  . MET B 1 16  ? -15.03095 19.98855 -42.83443 1.000 22.41834 ? 17  MET B CG  1 
ATOM   2394 S SD  . MET B 1 16  ? -16.28764 20.75781 -43.90792 1.000 24.85801 ? 17  MET B SD  1 
ATOM   2395 C CE  . MET B 1 16  ? -15.29150 21.88723 -44.88873 1.000 24.91123 ? 17  MET B CE  1 
ATOM   2396 N N   . VAL B 1 17  ? -13.12689 18.24669 -46.63069 1.000 21.57838 ? 18  VAL B N   1 
ATOM   2397 C CA  . VAL B 1 17  ? -12.00942 17.85119 -47.48655 1.000 24.70251 ? 18  VAL B CA  1 
ATOM   2398 C C   . VAL B 1 17  ? -11.30705 19.10226 -48.00632 1.000 24.38695 ? 18  VAL B C   1 
ATOM   2399 O O   . VAL B 1 17  ? -11.77745 20.23244 -47.84360 1.000 22.82243 ? 18  VAL B O   1 
ATOM   2400 C CB  . VAL B 1 17  ? -12.45518 16.94620 -48.66298 1.000 22.66004 ? 18  VAL B CB  1 
ATOM   2401 C CG1 . VAL B 1 17  ? -12.90204 15.57827 -48.14231 1.000 25.30413 ? 18  VAL B CG1 1 
ATOM   2402 C CG2 . VAL B 1 17  ? -13.57715 17.59703 -49.44263 1.000 21.35061 ? 18  VAL B CG2 1 
ATOM   2403 N N   . GLN B 1 18  ? -10.16121 18.89606 -48.63964 1.000 24.07319 ? 19  GLN B N   1 
ATOM   2404 C CA  . GLN B 1 18  ? -9.44389  19.97742 -49.29969 1.000 22.55387 ? 19  GLN B CA  1 
ATOM   2405 C C   . GLN B 1 18  ? -9.59166  19.78364 -50.79472 1.000 24.92458 ? 19  GLN B C   1 
ATOM   2406 O O   . GLN B 1 18  ? -9.40047  18.66949 -51.29481 1.000 27.81241 ? 19  GLN B O   1 
ATOM   2407 C CB  . GLN B 1 18  ? -7.95968  19.99530 -48.92391 1.000 26.50477 ? 19  GLN B CB  1 
ATOM   2408 C CG  . GLN B 1 18  ? -7.13413  20.98198 -49.75166 1.000 26.09015 ? 19  GLN B CG  1 
ATOM   2409 C CD  . GLN B 1 18  ? -5.68848  21.05541 -49.31806 1.000 32.38492 ? 19  GLN B CD  1 
ATOM   2410 O OE1 . GLN B 1 18  ? -5.18403  20.15975 -48.66243 1.000 38.27132 ? 19  GLN B OE1 1 
ATOM   2411 N NE2 . GLN B 1 18  ? -5.01709  22.13398 -49.68001 1.000 37.04994 ? 19  GLN B NE2 1 
ATOM   2412 N N   . VAL B 1 19  ? -9.91959  20.85515 -51.50541 1.000 24.61472 ? 20  VAL B N   1 
ATOM   2413 C CA  . VAL B 1 19  ? -10.08867 20.81207 -52.95377 1.000 23.67747 ? 20  VAL B CA  1 
ATOM   2414 C C   . VAL B 1 19  ? -9.02782  21.70104 -53.58851 1.000 24.14449 ? 20  VAL B C   1 
ATOM   2415 O O   . VAL B 1 19  ? -8.87142  22.86822 -53.20610 1.000 23.91740 ? 20  VAL B O   1 
ATOM   2416 C CB  . VAL B 1 19  ? -11.50578 21.23563 -53.38148 1.000 24.23957 ? 20  VAL B CB  1 
ATOM   2417 C CG1 . VAL B 1 19  ? -11.65068 21.13009 -54.91220 1.000 26.47081 ? 20  VAL B CG1 1 
ATOM   2418 C CG2 . VAL B 1 19  ? -12.54489 20.36740 -52.70132 1.000 20.67394 ? 20  VAL B CG2 1 
ATOM   2419 N N   . THR B 1 20  ? -8.29542  21.14756 -54.55644 1.000 26.94153 ? 21  THR B N   1 
ATOM   2420 C CA  . THR B 1 20  ? -7.24529  21.87847 -55.25830 1.000 30.90716 ? 21  THR B CA  1 
ATOM   2421 C C   . THR B 1 20  ? -7.54092  21.88431 -56.75310 1.000 30.86422 ? 21  THR B C   1 
ATOM   2422 O O   . THR B 1 20  ? -7.82727  20.83518 -57.33215 1.000 31.75986 ? 21  THR B O   1 
ATOM   2423 C CB  . THR B 1 20  ? -5.85996  21.27412 -54.99259 1.000 31.59507 ? 21  THR B CB  1 
ATOM   2424 O OG1 . THR B 1 20  ? -5.54035  21.40040 -53.60113 1.000 31.82507 ? 21  THR B OG1 1 
ATOM   2425 C CG2 . THR B 1 20  ? -4.80357  22.03166 -55.78322 1.000 34.98287 ? 21  THR B CG2 1 
ATOM   2426 N N   . CYS B 1 21  ? -7.49362  23.07071 -57.36520 1.000 32.48215 ? 22  CYS B N   1 
ATOM   2427 C CA  . CYS B 1 21  ? -7.65716  23.22418 -58.81182 1.000 34.61563 ? 22  CYS B CA  1 
ATOM   2428 C C   . CYS B 1 21  ? -6.57463  24.17525 -59.29582 1.000 36.75806 ? 22  CYS B C   1 
ATOM   2429 O O   . CYS B 1 21  ? -6.58761  25.36087 -58.94961 1.000 36.31254 ? 22  CYS B O   1 
ATOM   2430 C CB  . CYS B 1 21  ? -9.04148  23.75404 -59.18264 1.000 33.58334 ? 22  CYS B CB  1 
ATOM   2431 S SG  . CYS B 1 21  ? -9.30505  23.88314 -60.99012 1.000 33.93995 ? 22  CYS B SG  1 
ATOM   2432 N N   . GLY B 1 22  ? -5.64114  23.65840 -60.08377 1.000 41.19616 ? 23  GLY B N   1 
ATOM   2433 C CA  . GLY B 1 22  ? -4.50173  24.46832 -60.46523 1.000 41.01742 ? 23  GLY B CA  1 
ATOM   2434 C C   . GLY B 1 22  ? -3.70439  24.83367 -59.23302 1.000 41.43392 ? 23  GLY B C   1 
ATOM   2435 O O   . GLY B 1 22  ? -3.35727  23.97755 -58.41088 1.000 41.30417 ? 23  GLY B O   1 
ATOM   2436 N N   . SER B 1 23  ? -3.42864  26.12441 -59.08201 1.000 40.17933 ? 24  SER B N   1 
ATOM   2437 C CA  . SER B 1 23  ? -2.66707  26.62323 -57.95019 1.000 44.47346 ? 24  SER B CA  1 
ATOM   2438 C C   . SER B 1 23  ? -3.55622  27.15981 -56.83476 1.000 43.56887 ? 24  SER B C   1 
ATOM   2439 O O   . SER B 1 23  ? -3.04918  27.77969 -55.89738 1.000 47.77608 ? 24  SER B O   1 
ATOM   2440 C CB  . SER B 1 23  ? -1.70259  27.71579 -58.40645 1.000 46.97522 ? 24  SER B CB  1 
ATOM   2441 O OG  . SER B 1 23  ? -2.41610  28.89010 -58.74558 1.000 56.39356 ? 24  SER B OG  1 
ATOM   2442 N N   . MET B 1 24  ? -4.86186  26.94231 -56.91008 1.000 41.55365 ? 25  MET B N   1 
ATOM   2443 C CA  . MET B 1 24  ? -5.78351  27.43532 -55.90082 1.000 37.12657 ? 25  MET B CA  1 
ATOM   2444 C C   . MET B 1 24  ? -6.28214  26.27904 -55.04367 1.000 36.89310 ? 25  MET B C   1 
ATOM   2445 O O   . MET B 1 24  ? -6.46939  25.15694 -55.53642 1.000 31.68788 ? 25  MET B O   1 
ATOM   2446 C CB  . MET B 1 24  ? -6.95254  28.16781 -56.54890 1.000 41.47900 ? 25  MET B CB  1 
ATOM   2447 C CG  . MET B 1 24  ? -7.42682  29.34572 -55.73094 1.000 49.61064 ? 25  MET B CG  1 
ATOM   2448 S SD  . MET B 1 24  ? -8.05502  30.65598 -56.78737 1.000 64.43011 ? 25  MET B SD  1 
ATOM   2449 C CE  . MET B 1 24  ? -6.59965  30.97763 -57.78348 1.000 56.45096 ? 25  MET B CE  1 
ATOM   2450 N N   . THR B 1 25  ? -6.47944  26.55210 -53.75555 1.000 31.66542 ? 26  THR B N   1 
ATOM   2451 C CA  . THR B 1 25  ? -6.88767  25.50459 -52.83536 1.000 30.84815 ? 26  THR B CA  1 
ATOM   2452 C C   . THR B 1 25  ? -7.83061  26.08769 -51.79476 1.000 28.65220 ? 26  THR B C   1 
ATOM   2453 O O   . THR B 1 25  ? -7.64416  27.21820 -51.33743 1.000 32.92193 ? 26  THR B O   1 
ATOM   2454 C CB  . THR B 1 25  ? -5.67730  24.84329 -52.16593 1.000 31.48785 ? 26  THR B CB  1 
ATOM   2455 O OG1 . THR B 1 25  ? -6.11631  23.68618 -51.44590 1.000 35.88261 ? 26  THR B OG1 1 
ATOM   2456 C CG2 . THR B 1 25  ? -4.98398  25.79970 -51.20463 1.000 27.65602 ? 26  THR B CG2 1 
ATOM   2457 N N   . LEU B 1 26  ? -8.85749  25.32197 -51.45023 1.000 24.40081 ? 27  LEU B N   1 
ATOM   2458 C CA  . LEU B 1 26  ? -9.79754  25.72199 -50.40229 1.000 24.43900 ? 27  LEU B CA  1 
ATOM   2459 C C   . LEU B 1 26  ? -10.46351 24.45934 -49.86135 1.000 25.09047 ? 27  LEU B C   1 
ATOM   2460 O O   . LEU B 1 26  ? -10.01999 23.33928 -50.13911 1.000 23.57913 ? 27  LEU B O   1 
ATOM   2461 C CB  . LEU B 1 26  ? -10.80708 26.74595 -50.93482 1.000 26.58490 ? 27  LEU B CB  1 
ATOM   2462 C CG  . LEU B 1 26  ? -11.33821 26.52992 -52.35723 1.000 26.37185 ? 27  LEU B CG  1 
ATOM   2463 C CD1 . LEU B 1 26  ? -12.09304 25.21268 -52.49648 1.000 21.88612 ? 27  LEU B CD1 1 
ATOM   2464 C CD2 . LEU B 1 26  ? -12.25277 27.69411 -52.74396 1.000 26.13274 ? 27  LEU B CD2 1 
ATOM   2465 N N   . ASN B 1 27  ? -11.54646 24.63555 -49.10885 1.000 22.34710 ? 28  ASN B N   1 
ATOM   2466 C CA  . ASN B 1 27  ? -12.23699 23.53452 -48.44784 1.000 24.53621 ? 28  ASN B CA  1 
ATOM   2467 C C   . ASN B 1 27  ? -13.41542 23.05003 -49.27866 1.000 24.44948 ? 28  ASN B C   1 
ATOM   2468 O O   . ASN B 1 27  ? -14.00445 23.80805 -50.05394 1.000 25.55954 ? 28  ASN B O   1 
ATOM   2469 C CB  . ASN B 1 27  ? -12.74164 23.96153 -47.06422 1.000 22.76949 ? 28  ASN B CB  1 
ATOM   2470 C CG  . ASN B 1 27  ? -11.63907 24.55667 -46.19428 1.000 25.65784 ? 28  ASN B CG  1 
ATOM   2471 O OD1 . ASN B 1 27  ? -10.82455 23.83099 -45.64270 1.000 24.19269 ? 28  ASN B OD1 1 
ATOM   2472 N ND2 . ASN B 1 27  ? -11.61585 25.89079 -46.07291 1.000 22.83717 ? 28  ASN B ND2 1 
ATOM   2473 N N   . GLY B 1 28  ? -13.75750 21.76952 -49.10391 1.000 23.70614 ? 29  GLY B N   1 
ATOM   2474 C CA  . GLY B 1 28  ? -14.95317 21.21648 -49.69874 1.000 21.77913 ? 29  GLY B CA  1 
ATOM   2475 C C   . GLY B 1 28  ? -15.73066 20.38430 -48.69345 1.000 23.71629 ? 29  GLY B C   1 
ATOM   2476 O O   . GLY B 1 28  ? -15.20304 19.95231 -47.66848 1.000 22.09139 ? 29  GLY B O   1 
ATOM   2477 N N   . LEU B 1 29  ? -17.00034 20.14564 -49.02204 1.000 21.32268 ? 30  LEU B N   1 
ATOM   2478 C CA  . LEU B 1 29  ? -17.90035 19.35629 -48.18701 1.000 18.41119 ? 30  LEU B CA  1 
ATOM   2479 C C   . LEU B 1 29  ? -18.25024 18.05675 -48.90944 1.000 20.60258 ? 30  LEU B C   1 
ATOM   2480 O O   . LEU B 1 29  ? -18.87112 18.08631 -49.98263 1.000 21.76405 ? 30  LEU B O   1 
ATOM   2481 C CB  . LEU B 1 29  ? -19.17239 20.13354 -47.85154 1.000 20.44923 ? 30  LEU B CB  1 
ATOM   2482 C CG  . LEU B 1 29  ? -20.14212 19.39885 -46.90373 1.000 22.84621 ? 30  LEU B CG  1 
ATOM   2483 C CD1 . LEU B 1 29  ? -19.55373 19.22401 -45.49623 1.000 20.91011 ? 30  LEU B CD1 1 
ATOM   2484 C CD2 . LEU B 1 29  ? -21.48920 20.10292 -46.82448 1.000 25.48914 ? 30  LEU B CD2 1 
ATOM   2485 N N   . TRP B 1 30  ? -17.89182 16.93216 -48.29596 1.000 20.72619 ? 31  TRP B N   1 
ATOM   2486 C CA  . TRP B 1 30  ? -18.01000 15.59923 -48.89599 1.000 22.86891 ? 31  TRP B CA  1 
ATOM   2487 C C   . TRP B 1 30  ? -19.22426 14.88579 -48.30901 1.000 21.24339 ? 31  TRP B C   1 
ATOM   2488 O O   . TRP B 1 30  ? -19.21425 14.48627 -47.14555 1.000 22.94533 ? 31  TRP B O   1 
ATOM   2489 C CB  . TRP B 1 30  ? -16.72419 14.81455 -48.64692 1.000 21.89623 ? 31  TRP B CB  1 
ATOM   2490 C CG  . TRP B 1 30  ? -16.67984 13.41436 -49.16587 1.000 24.74341 ? 31  TRP B CG  1 
ATOM   2491 C CD1 . TRP B 1 30  ? -17.30422 12.91112 -50.28256 1.000 22.88789 ? 31  TRP B CD1 1 
ATOM   2492 C CD2 . TRP B 1 30  ? -15.91342 12.34510 -48.61410 1.000 25.11217 ? 31  TRP B CD2 1 
ATOM   2493 N NE1 . TRP B 1 30  ? -16.97756 11.57021 -50.43930 1.000 28.15729 ? 31  TRP B NE1 1 
ATOM   2494 C CE2 . TRP B 1 30  ? -16.12468 11.20768 -49.42649 1.000 29.15078 ? 31  TRP B CE2 1 
ATOM   2495 C CE3 . TRP B 1 30  ? -15.07393 12.23337 -47.49778 1.000 27.23129 ? 31  TRP B CE3 1 
ATOM   2496 C CZ2 . TRP B 1 30  ? -15.51704 9.98068  -49.15931 1.000 27.87776 ? 31  TRP B CZ2 1 
ATOM   2497 C CZ3 . TRP B 1 30  ? -14.47750 11.00829 -47.23420 1.000 28.96064 ? 31  TRP B CZ3 1 
ATOM   2498 C CH2 . TRP B 1 30  ? -14.71035 9.90037  -48.05478 1.000 27.74015 ? 31  TRP B CH2 1 
ATOM   2499 N N   . LEU B 1 31  ? -20.26398 14.72075 -49.12600 1.000 23.53200 ? 32  LEU B N   1 
ATOM   2500 C CA  . LEU B 1 31  ? -21.50904 14.06914 -48.74687 1.000 23.94145 ? 32  LEU B CA  1 
ATOM   2501 C C   . LEU B 1 31  ? -21.81619 12.98753 -49.77258 1.000 24.42798 ? 32  LEU B C   1 
ATOM   2502 O O   . LEU B 1 31  ? -21.86319 13.27402 -50.97007 1.000 25.80185 ? 32  LEU B O   1 
ATOM   2503 C CB  . LEU B 1 31  ? -22.66836 15.07065 -48.70545 1.000 26.89694 ? 32  LEU B CB  1 
ATOM   2504 C CG  . LEU B 1 31  ? -22.49898 16.28716 -47.79573 1.000 23.00385 ? 32  LEU B CG  1 
ATOM   2505 C CD1 . LEU B 1 31  ? -23.70373 17.21356 -47.93951 1.000 23.90350 ? 32  LEU B CD1 1 
ATOM   2506 C CD2 . LEU B 1 31  ? -22.37933 15.81276 -46.36805 1.000 24.46748 ? 32  LEU B CD2 1 
ATOM   2507 N N   . ASP B 1 32  ? -22.06068 11.76516 -49.30483 1.000 27.68571 ? 33  ASP B N   1 
ATOM   2508 C CA  . ASP B 1 32  ? -22.23812 10.62995 -50.21595 1.000 29.45889 ? 33  ASP B CA  1 
ATOM   2509 C C   . ASP B 1 32  ? -21.11333 10.61957 -51.24178 1.000 26.84583 ? 33  ASP B C   1 
ATOM   2510 O O   . ASP B 1 32  ? -19.94090 10.64201 -50.86318 1.000 29.09372 ? 33  ASP B O   1 
ATOM   2511 C CB  . ASP B 1 32  ? -23.60031 10.68370 -50.90947 1.000 29.27824 ? 33  ASP B CB  1 
ATOM   2512 C CG  . ASP B 1 32  ? -24.74351 10.71157 -49.92526 1.000 34.66417 ? 33  ASP B CG  1 
ATOM   2513 O OD1 . ASP B 1 32  ? -24.72981 9.88312  -48.99703 1.000 38.20178 ? 33  ASP B OD1 1 
ATOM   2514 O OD2 . ASP B 1 32  ? -25.64158 11.57483 -50.06621 1.000 40.57980 ? 33  ASP B OD2 1 
ATOM   2515 N N   . ASN B 1 33  ? -21.45083 10.64442 -52.53496 1.000 25.48644 ? 34  ASN B N   1 
ATOM   2516 C CA  . ASN B 1 33  ? -20.46510 10.64747 -53.61016 1.000 25.44940 ? 34  ASN B CA  1 
ATOM   2517 C C   . ASN B 1 33  ? -20.19048 12.03111 -54.17860 1.000 29.00521 ? 34  ASN B C   1 
ATOM   2518 O O   . ASN B 1 33  ? -19.70896 12.13539 -55.30970 1.000 29.39242 ? 34  ASN B O   1 
ATOM   2519 C CB  . ASN B 1 33  ? -20.92249 9.73716  -54.74924 1.000 33.46765 ? 34  ASN B CB  1 
ATOM   2520 C CG  . ASN B 1 33  ? -20.52441 8.33021  -54.52887 1.000 37.07083 ? 34  ASN B CG  1 
ATOM   2521 O OD1 . ASN B 1 33  ? -21.37083 7.45156  -54.36443 1.000 43.83773 ? 34  ASN B OD1 1 
ATOM   2522 N ND2 . ASN B 1 33  ? -19.21492 8.09082  -54.48907 1.000 36.79900 ? 34  ASN B ND2 1 
ATOM   2523 N N   . THR B 1 34  ? -20.48772 13.09533 -53.44080 1.000 26.51356 ? 35  THR B N   1 
ATOM   2524 C CA  . THR B 1 34  ? -20.40270 14.44637 -53.97484 1.000 24.73394 ? 35  THR B CA  1 
ATOM   2525 C C   . THR B 1 34  ? -19.49697 15.29030 -53.09231 1.000 24.73520 ? 35  THR B C   1 
ATOM   2526 O O   . THR B 1 34  ? -19.52855 15.15801 -51.86902 1.000 24.78968 ? 35  THR B O   1 
ATOM   2527 C CB  . THR B 1 34  ? -21.80267 15.07261 -54.06250 1.000 30.09842 ? 35  THR B CB  1 
ATOM   2528 O OG1 . THR B 1 34  ? -22.58934 14.34878 -55.01375 1.000 29.65449 ? 35  THR B OG1 1 
ATOM   2529 C CG2 . THR B 1 34  ? -21.74236 16.53390 -54.46547 1.000 29.05197 ? 35  THR B CG2 1 
ATOM   2530 N N   . VAL B 1 35  ? -18.67598 16.14344 -53.71346 1.000 27.47738 ? 36  VAL B N   1 
ATOM   2531 C CA  . VAL B 1 35  ? -17.90996 17.16135 -52.99436 1.000 26.18263 ? 36  VAL B CA  1 
ATOM   2532 C C   . VAL B 1 35  ? -18.37264 18.52482 -53.48565 1.000 26.25131 ? 36  VAL B C   1 
ATOM   2533 O O   . VAL B 1 35  ? -18.31808 18.81038 -54.68933 1.000 28.42636 ? 36  VAL B O   1 
ATOM   2534 C CB  . VAL B 1 35  ? -16.38925 16.98964 -53.16829 1.000 22.91992 ? 36  VAL B CB  1 
ATOM   2535 C CG1 . VAL B 1 35  ? -15.63272 18.19434 -52.59018 1.000 22.80120 ? 36  VAL B CG1 1 
ATOM   2536 C CG2 . VAL B 1 35  ? -15.92626 15.69308 -52.47179 1.000 23.50216 ? 36  VAL B CG2 1 
ATOM   2537 N N   . TRP B 1 36  ? -18.87050 19.34518 -52.55736 1.000 24.66537 ? 37  TRP B N   1 
ATOM   2538 C CA  . TRP B 1 36  ? -19.30658 20.70960 -52.83178 1.000 26.42246 ? 37  TRP B CA  1 
ATOM   2539 C C   . TRP B 1 36  ? -18.17076 21.66345 -52.50182 1.000 26.65271 ? 37  TRP B C   1 
ATOM   2540 O O   . TRP B 1 36  ? -17.52390 21.52236 -51.45782 1.000 25.92447 ? 37  TRP B O   1 
ATOM   2541 C CB  . TRP B 1 36  ? -20.52752 21.06559 -51.97366 1.000 27.12833 ? 37  TRP B CB  1 
ATOM   2542 C CG  . TRP B 1 36  ? -21.72905 20.20020 -52.18360 1.000 28.69194 ? 37  TRP B CG  1 
ATOM   2543 C CD1 . TRP B 1 36  ? -22.02761 19.02910 -51.54523 1.000 29.02683 ? 37  TRP B CD1 1 
ATOM   2544 C CD2 . TRP B 1 36  ? -22.81574 20.45792 -53.07234 1.000 29.50566 ? 37  TRP B CD2 1 
ATOM   2545 N NE1 . TRP B 1 36  ? -23.22102 18.53465 -52.00125 1.000 29.23127 ? 37  TRP B NE1 1 
ATOM   2546 C CE2 . TRP B 1 36  ? -23.73008 19.39505 -52.93365 1.000 30.21199 ? 37  TRP B CE2 1 
ATOM   2547 C CE3 . TRP B 1 36  ? -23.10184 21.48244 -53.97343 1.000 30.92870 ? 37  TRP B CE3 1 
ATOM   2548 C CZ2 . TRP B 1 36  ? -24.91196 19.32493 -53.66540 1.000 38.31894 ? 37  TRP B CZ2 1 
ATOM   2549 C CZ3 . TRP B 1 36  ? -24.27367 21.41025 -54.70738 1.000 36.06800 ? 37  TRP B CZ3 1 
ATOM   2550 C CH2 . TRP B 1 36  ? -25.16434 20.34191 -54.54845 1.000 36.53140 ? 37  TRP B CH2 1 
ATOM   2551 N N   . CYS B 1 37  ? -17.93550 22.64567 -53.36899 1.000 25.17912 ? 38  CYS B N   1 
ATOM   2552 C CA  . CYS B 1 37  ? -16.93764 23.66398 -53.06054 1.000 25.15695 ? 38  CYS B CA  1 
ATOM   2553 C C   . CYS B 1 37  ? -17.25693 24.93089 -53.84965 1.000 26.23044 ? 38  CYS B C   1 
ATOM   2554 O O   . CYS B 1 37  ? -18.03971 24.89018 -54.80715 1.000 24.48146 ? 38  CYS B O   1 
ATOM   2555 C CB  . CYS B 1 37  ? -15.51889 23.15809 -53.36936 1.000 24.34811 ? 38  CYS B CB  1 
ATOM   2556 S SG  . CYS B 1 37  ? -15.06170 23.12358 -55.12522 1.000 28.57250 ? 38  CYS B SG  1 
ATOM   2557 N N   . PRO B 1 38  ? -16.68398 26.07318 -53.46280 1.000 26.78713 ? 39  PRO B N   1 
ATOM   2558 C CA  . PRO B 1 38  ? -16.91837 27.30429 -54.23168 1.000 26.85981 ? 39  PRO B CA  1 
ATOM   2559 C C   . PRO B 1 38  ? -16.28135 27.24057 -55.61138 1.000 25.99434 ? 39  PRO B C   1 
ATOM   2560 O O   . PRO B 1 38  ? -15.13049 26.82625 -55.77886 1.000 24.43833 ? 39  PRO B O   1 
ATOM   2561 C CB  . PRO B 1 38  ? -16.26890 28.39612 -53.37491 1.000 27.27942 ? 39  PRO B CB  1 
ATOM   2562 C CG  . PRO B 1 38  ? -16.20039 27.82383 -52.00042 1.000 26.44587 ? 39  PRO B CG  1 
ATOM   2563 C CD  . PRO B 1 38  ? -15.99000 26.34957 -52.19031 1.000 23.75746 ? 39  PRO B CD  1 
ATOM   2564 N N   . ARG B 1 39  ? -17.04262 27.68527 -56.61079 1.000 27.52861 ? 40  ARG B N   1 
ATOM   2565 C CA  . ARG B 1 39  ? -16.55623 27.60272 -57.97943 1.000 28.00633 ? 40  ARG B CA  1 
ATOM   2566 C C   . ARG B 1 39  ? -15.34885 28.49359 -58.22061 1.000 28.93407 ? 40  ARG B C   1 
ATOM   2567 O O   . ARG B 1 39  ? -14.63654 28.27690 -59.20514 1.000 30.13003 ? 40  ARG B O   1 
ATOM   2568 C CB  . ARG B 1 39  ? -17.67728 27.95517 -58.96876 1.000 29.65987 ? 40  ARG B CB  1 
ATOM   2569 C CG  . ARG B 1 39  ? -18.03475 29.44992 -59.01368 1.000 28.16249 ? 40  ARG B CG  1 
ATOM   2570 C CD  . ARG B 1 39  ? -19.11553 29.73397 -60.05388 1.000 29.46622 ? 40  ARG B CD  1 
ATOM   2571 N NE  . ARG B 1 39  ? -19.60007 31.11423 -59.96035 1.000 30.71340 ? 40  ARG B NE  1 
ATOM   2572 C CZ  . ARG B 1 39  ? -20.42663 31.69150 -60.83402 1.000 36.69035 ? 40  ARG B CZ  1 
ATOM   2573 N NH1 . ARG B 1 39  ? -20.87101 31.02279 -61.89242 1.000 33.38275 ? 40  ARG B NH1 1 
ATOM   2574 N NH2 . ARG B 1 39  ? -20.80440 32.94625 -60.65365 1.000 32.25467 ? 40  ARG B NH2 1 
ATOM   2575 N N   . HIS B 1 40  ? -15.07365 29.47699 -57.34452 1.000 29.81367 ? 41  HIS B N   1 
ATOM   2576 C CA  . HIS B 1 40  ? -13.91607 30.32069 -57.63861 1.000 29.87284 ? 41  HIS B CA  1 
ATOM   2577 C C   . HIS B 1 40  ? -12.59216 29.59504 -57.44518 1.000 31.87945 ? 41  HIS B C   1 
ATOM   2578 O O   . HIS B 1 40  ? -11.54760 30.19034 -57.73348 1.000 33.07780 ? 41  HIS B O   1 
ATOM   2579 C CB  . HIS B 1 40  ? -13.93528 31.64877 -56.84320 1.000 31.54330 ? 41  HIS B CB  1 
ATOM   2580 C CG  . HIS B 1 40  ? -13.83459 31.52403 -55.34140 1.000 32.43926 ? 41  HIS B CG  1 
ATOM   2581 N ND1 . HIS B 1 40  ? -12.68020 31.14439 -54.68877 1.000 28.94530 ? 41  HIS B ND1 1 
ATOM   2582 C CD2 . HIS B 1 40  ? -14.72389 31.83670 -54.36590 1.000 30.71575 ? 41  HIS B CD2 1 
ATOM   2583 C CE1 . HIS B 1 40  ? -12.87755 31.17930 -53.38152 1.000 32.95288 ? 41  HIS B CE1 1 
ATOM   2584 N NE2 . HIS B 1 40  ? -14.10990 31.59671 -53.15871 1.000 29.29982 ? 41  HIS B NE2 1 
ATOM   2585 N N   . VAL B 1 41  ? -12.59535 28.32249 -57.02458 1.000 27.05444 ? 42  VAL B N   1 
ATOM   2586 C CA  . VAL B 1 41  ? -11.34927 27.56863 -57.03378 1.000 26.18978 ? 42  VAL B CA  1 
ATOM   2587 C C   . VAL B 1 41  ? -10.83130 27.39141 -58.46227 1.000 31.19132 ? 42  VAL B C   1 
ATOM   2588 O O   . VAL B 1 41  ? -9.63002  27.17762 -58.66017 1.000 30.07038 ? 42  VAL B O   1 
ATOM   2589 C CB  . VAL B 1 41  ? -11.53527 26.20325 -56.32846 1.000 29.61263 ? 42  VAL B CB  1 
ATOM   2590 C CG1 . VAL B 1 41  ? -12.26974 25.20031 -57.23509 1.000 26.55470 ? 42  VAL B CG1 1 
ATOM   2591 C CG2 . VAL B 1 41  ? -10.18937 25.64892 -55.86698 1.000 26.96861 ? 42  VAL B CG2 1 
ATOM   2592 N N   . MET B 1 42  ? -11.71714 27.48358 -59.46283 1.000 27.79742 ? 43  MET B N   1 
ATOM   2593 C CA  . MET B 1 42  ? -11.34911 27.40471 -60.87877 1.000 33.34537 ? 43  MET B CA  1 
ATOM   2594 C C   . MET B 1 42  ? -10.74177 28.68918 -61.41742 1.000 38.13876 ? 43  MET B C   1 
ATOM   2595 O O   . MET B 1 42  ? -10.20938 28.68175 -62.53211 1.000 47.11047 ? 43  MET B O   1 
ATOM   2596 C CB  . MET B 1 42  ? -12.57096 27.07566 -61.74231 1.000 32.02545 ? 43  MET B CB  1 
ATOM   2597 C CG  . MET B 1 42  ? -13.03008 25.64145 -61.70504 1.000 34.56127 ? 43  MET B CG  1 
ATOM   2598 S SD  . MET B 1 42  ? -14.43573 25.42766 -62.81478 1.000 35.94758 ? 43  MET B SD  1 
ATOM   2599 C CE  . MET B 1 42  ? -15.31631 26.94437 -62.48957 1.000 38.30800 ? 43  MET B CE  1 
ATOM   2600 N N   . CYS B 1 43  ? -10.82403 29.78438 -60.68277 1.000 40.27282 ? 44  CYS B N   1 
ATOM   2601 C CA  . CYS B 1 43  ? -10.41687 31.07393 -61.22022 1.000 43.46310 ? 44  CYS B CA  1 
ATOM   2602 C C   . CYS B 1 43  ? -8.89962  31.22143 -61.15832 1.000 47.44281 ? 44  CYS B C   1 
ATOM   2603 O O   . CYS B 1 43  ? -8.31872  31.08034 -60.07777 1.000 45.58641 ? 44  CYS B O   1 
ATOM   2604 C CB  . CYS B 1 43  ? -11.10526 32.19040 -60.44643 1.000 43.88267 ? 44  CYS B CB  1 
ATOM   2605 S SG  . CYS B 1 43  ? -10.80077 33.82920 -61.09394 1.000 57.21434 ? 44  CYS B SG  1 
ATOM   2606 N N   . PRO B 1 44  ? -8.22102  31.48553 -62.28151 1.000 52.34059 ? 45  PRO B N   1 
ATOM   2607 C CA  . PRO B 1 44  ? -6.77170  31.73333 -62.23304 1.000 53.32971 ? 45  PRO B CA  1 
ATOM   2608 C C   . PRO B 1 44  ? -6.43913  32.95046 -61.38143 1.000 53.76725 ? 45  PRO B C   1 
ATOM   2609 O O   . PRO B 1 44  ? -7.19346  33.92366 -61.32742 1.000 55.00796 ? 45  PRO B O   1 
ATOM   2610 C CB  . PRO B 1 44  ? -6.39818  31.96324 -63.70256 1.000 56.72925 ? 45  PRO B CB  1 
ATOM   2611 C CG  . PRO B 1 44  ? -7.49164  31.31465 -64.48578 1.000 55.48474 ? 45  PRO B CG  1 
ATOM   2612 C CD  . PRO B 1 44  ? -8.73609  31.45045 -63.66062 1.000 51.51155 ? 45  PRO B CD  1 
ATOM   2613 N N   . ALA B 1 45  ? -5.27905  32.89198 -60.72086 1.000 56.52390 ? 46  ALA B N   1 
ATOM   2614 C CA  . ALA B 1 45  ? -4.94755  33.87963 -59.69549 1.000 59.80635 ? 46  ALA B CA  1 
ATOM   2615 C C   . ALA B 1 45  ? -4.69956  35.27291 -60.26656 1.000 65.56733 ? 46  ALA B C   1 
ATOM   2616 O O   . ALA B 1 45  ? -4.79318  36.25748 -59.52318 1.000 64.33203 ? 46  ALA B O   1 
ATOM   2617 C CB  . ALA B 1 45  ? -3.72790  33.41665 -58.89358 1.000 61.80889 ? 46  ALA B CB  1 
ATOM   2618 N N   . ASP B 1 46  ? -4.38621  35.37969 -61.55972 1.000 65.71846 ? 47  ASP B N   1 
ATOM   2619 C CA  . ASP B 1 46  ? -4.21363  36.66802 -62.22242 1.000 66.72555 ? 47  ASP B CA  1 
ATOM   2620 C C   . ASP B 1 46  ? -5.51241  37.20910 -62.80379 1.000 62.23101 ? 47  ASP B C   1 
ATOM   2621 O O   . ASP B 1 46  ? -5.54244  38.35913 -63.25524 1.000 62.22602 ? 47  ASP B O   1 
ATOM   2622 C CB  . ASP B 1 46  ? -3.16347  36.56084 -63.34413 1.000 64.87987 ? 47  ASP B CB  1 
ATOM   2623 C CG  . ASP B 1 46  ? -3.44112  35.40813 -64.31207 1.000 69.49984 ? 47  ASP B CG  1 
ATOM   2624 O OD1 . ASP B 1 46  ? -4.07688  34.40911 -63.90341 1.000 65.25057 ? 47  ASP B OD1 1 
ATOM   2625 O OD2 . ASP B 1 46  ? -3.02062  35.50310 -65.48900 1.000 71.89479 ? 47  ASP B OD2 1 
ATOM   2626 N N   . GLN B 1 47  ? -6.58196  36.41523 -62.78216 1.000 62.40446 ? 48  GLN B N   1 
ATOM   2627 C CA  . GLN B 1 47  ? -7.81088  36.70257 -63.50802 1.000 59.18812 ? 48  GLN B CA  1 
ATOM   2628 C C   . GLN B 1 47  ? -8.99264  36.88636 -62.56442 1.000 53.94956 ? 48  GLN B C   1 
ATOM   2629 O O   . GLN B 1 47  ? -10.13461 36.59041 -62.92503 1.000 47.27073 ? 48  GLN B O   1 
ATOM   2630 C CB  . GLN B 1 47  ? -8.10049  35.58479 -64.50244 1.000 57.74330 ? 48  GLN B CB  1 
ATOM   2631 C CG  . GLN B 1 47  ? -7.02834  35.42323 -65.55394 1.000 60.98212 ? 48  GLN B CG  1 
ATOM   2632 C CD  . GLN B 1 47  ? -7.49474  34.57529 -66.70335 1.000 58.57356 ? 48  GLN B CD  1 
ATOM   2633 O OE1 . GLN B 1 47  ? -6.69033  33.97966 -67.41178 1.000 64.35533 ? 48  GLN B OE1 1 
ATOM   2634 N NE2 . GLN B 1 47  ? -8.81062  34.49246 -66.88226 1.000 59.94909 ? 48  GLN B NE2 1 
ATOM   2635 N N   . LEU B 1 48  ? -8.72754  37.38410 -61.35381 1.000 57.26194 ? 49  LEU B N   1 
ATOM   2636 C CA  . LEU B 1 48  ? -9.76869  37.49308 -60.33750 1.000 57.56152 ? 49  LEU B CA  1 
ATOM   2637 C C   . LEU B 1 48  ? -10.80466 38.56348 -60.66635 1.000 56.84331 ? 49  LEU B C   1 
ATOM   2638 O O   . LEU B 1 48  ? -11.93559 38.47625 -60.17368 1.000 51.68927 ? 49  LEU B O   1 
ATOM   2639 C CB  . LEU B 1 48  ? -9.13247  37.78655 -58.97708 1.000 56.93350 ? 49  LEU B CB  1 
ATOM   2640 C CG  . LEU B 1 48  ? -7.98464  36.91278 -58.46959 1.000 56.96375 ? 49  LEU B CG  1 
ATOM   2641 C CD1 . LEU B 1 48  ? -7.79872  37.13539 -56.97696 1.000 63.04324 ? 49  LEU B CD1 1 
ATOM   2642 C CD2 . LEU B 1 48  ? -8.24414  35.44547 -58.75543 1.000 58.23515 ? 49  LEU B CD2 1 
ATOM   2643 N N   . SER B 1 49  ? -10.44737 39.53820 -61.51519 1.000 53.60652 ? 50  SER B N   1 
ATOM   2644 C CA  . SER B 1 49  ? -11.25732 40.74016 -61.71263 1.000 54.16117 ? 50  SER B CA  1 
ATOM   2645 C C   . SER B 1 49  ? -12.62530 40.42835 -62.30763 1.000 54.55062 ? 50  SER B C   1 
ATOM   2646 O O   . SER B 1 49  ? -13.61726 41.07552 -61.95696 1.000 56.65469 ? 50  SER B O   1 
ATOM   2647 C CB  . SER B 1 49  ? -10.50548 41.71823 -62.61123 1.000 55.02836 ? 50  SER B CB  1 
ATOM   2648 O OG  . SER B 1 49  ? -9.75588  41.00442 -63.57979 1.000 58.42702 ? 50  SER B OG  1 
ATOM   2649 N N   . ASP B 1 50  ? -12.69988 39.46763 -63.22724 1.000 53.65066 ? 51  ASP B N   1 
ATOM   2650 C CA  . ASP B 1 50  ? -13.99623 39.07471 -63.76664 1.000 56.04958 ? 51  ASP B CA  1 
ATOM   2651 C C   . ASP B 1 50  ? -13.85891 37.76081 -64.53201 1.000 61.06189 ? 51  ASP B C   1 
ATOM   2652 O O   . ASP B 1 50  ? -13.60585 37.76662 -65.74332 1.000 65.67718 ? 51  ASP B O   1 
ATOM   2653 C CB  . ASP B 1 50  ? -14.56770 40.19405 -64.65116 1.000 64.67073 ? 51  ASP B CB  1 
ATOM   2654 C CG  . ASP B 1 50  ? -15.67649 39.71800 -65.57877 1.000 65.01152 ? 51  ASP B CG  1 
ATOM   2655 O OD1 . ASP B 1 50  ? -16.75829 39.32391 -65.08042 1.000 65.35885 ? 51  ASP B OD1 1 
ATOM   2656 O OD2 . ASP B 1 50  ? -15.46491 39.75829 -66.81123 1.000 71.02057 ? 51  ASP B OD2 1 
ATOM   2657 N N   . PRO B 1 51  ? -13.99132 36.61862 -63.86046 1.000 57.33561 ? 52  PRO B N   1 
ATOM   2658 C CA  . PRO B 1 51  ? -13.86573 35.32971 -64.55154 1.000 52.40155 ? 52  PRO B CA  1 
ATOM   2659 C C   . PRO B 1 51  ? -15.13536 34.92621 -65.28008 1.000 48.54159 ? 52  PRO B C   1 
ATOM   2660 O O   . PRO B 1 51  ? -16.24975 35.28170 -64.89197 1.000 49.02685 ? 52  PRO B O   1 
ATOM   2661 C CB  . PRO B 1 51  ? -13.56667 34.34628 -63.41122 1.000 49.58138 ? 52  PRO B CB  1 
ATOM   2662 C CG  . PRO B 1 51  ? -14.14871 34.99143 -62.20129 1.000 48.72270 ? 52  PRO B CG  1 
ATOM   2663 C CD  . PRO B 1 51  ? -14.02189 36.47180 -62.39379 1.000 52.93314 ? 52  PRO B CD  1 
ATOM   2664 N N   . ASN B 1 52  ? -14.94835 34.14573 -66.34318 1.000 44.14229 ? 53  ASN B N   1 
ATOM   2665 C CA  . ASN B 1 52  ? -16.05145 33.54399 -67.09340 1.000 44.86660 ? 53  ASN B CA  1 
ATOM   2666 C C   . ASN B 1 52  ? -16.19377 32.09450 -66.62677 1.000 45.93632 ? 53  ASN B C   1 
ATOM   2667 O O   . ASN B 1 52  ? -15.50821 31.19759 -67.12950 1.000 41.87161 ? 53  ASN B O   1 
ATOM   2668 C CB  . ASN B 1 52  ? -15.79616 33.63985 -68.59728 1.000 46.52975 ? 53  ASN B CB  1 
ATOM   2669 C CG  . ASN B 1 52  ? -16.97833 33.17128 -69.43291 1.000 46.35002 ? 53  ASN B CG  1 
ATOM   2670 O OD1 . ASN B 1 52  ? -17.84584 32.44352 -68.95838 1.000 48.58095 ? 53  ASN B OD1 1 
ATOM   2671 N ND2 . ASN B 1 52  ? -17.01598 33.59809 -70.69136 1.000 49.56412 ? 53  ASN B ND2 1 
ATOM   2672 N N   . TYR B 1 53  ? -17.10938 31.86721 -65.67657 1.000 39.85943 ? 54  TYR B N   1 
ATOM   2673 C CA  . TYR B 1 53  ? -17.20839 30.56318 -65.02413 1.000 41.40683 ? 54  TYR B CA  1 
ATOM   2674 C C   . TYR B 1 53  ? -17.80099 29.50052 -65.93821 1.000 41.62293 ? 54  TYR B C   1 
ATOM   2675 O O   . TYR B 1 53  ? -17.48169 28.31341 -65.78885 1.000 42.03981 ? 54  TYR B O   1 
ATOM   2676 C CB  . TYR B 1 53  ? -18.03273 30.68107 -63.74057 1.000 38.21421 ? 54  TYR B CB  1 
ATOM   2677 C CG  . TYR B 1 53  ? -17.25499 31.34290 -62.63158 1.000 37.95414 ? 54  TYR B CG  1 
ATOM   2678 C CD1 . TYR B 1 53  ? -16.13317 30.73168 -62.08914 1.000 35.13591 ? 54  TYR B CD1 1 
ATOM   2679 C CD2 . TYR B 1 53  ? -17.60976 32.59659 -62.16070 1.000 37.86643 ? 54  TYR B CD2 1 
ATOM   2680 C CE1 . TYR B 1 53  ? -15.40172 31.34098 -61.08276 1.000 36.84701 ? 54  TYR B CE1 1 
ATOM   2681 C CE2 . TYR B 1 53  ? -16.89122 33.21126 -61.14856 1.000 37.68439 ? 54  TYR B CE2 1 
ATOM   2682 C CZ  . TYR B 1 53  ? -15.78918 32.57989 -60.61412 1.000 36.20978 ? 54  TYR B CZ  1 
ATOM   2683 O OH  . TYR B 1 53  ? -15.06299 33.19840 -59.61742 1.000 37.37372 ? 54  TYR B OH  1 
ATOM   2684 N N   . ASP B 1 54  ? -18.68027 29.89128 -66.86267 1.000 40.71591 ? 55  ASP B N   1 
ATOM   2685 C CA  . ASP B 1 54  ? -19.19276 28.93076 -67.83314 1.000 42.31621 ? 55  ASP B CA  1 
ATOM   2686 C C   . ASP B 1 54  ? -18.06295 28.40700 -68.71423 1.000 42.12446 ? 55  ASP B C   1 
ATOM   2687 O O   . ASP B 1 54  ? -18.01457 27.21340 -69.03948 1.000 43.90300 ? 55  ASP B O   1 
ATOM   2688 C CB  . ASP B 1 54  ? -20.29073 29.57607 -68.68428 1.000 47.79605 ? 55  ASP B CB  1 
ATOM   2689 C CG  . ASP B 1 54  ? -21.59026 29.80266 -67.91178 1.000 54.36492 ? 55  ASP B CG  1 
ATOM   2690 O OD1 . ASP B 1 54  ? -21.96079 28.95867 -67.06753 1.000 49.98298 ? 55  ASP B OD1 1 
ATOM   2691 O OD2 . ASP B 1 54  ? -22.24814 30.83426 -68.16052 1.000 57.20977 ? 55  ASP B OD2 1 
ATOM   2692 N N   . ALA B 1 55  ? -17.13072 29.28736 -69.08881 1.000 44.55421 ? 56  ALA B N   1 
ATOM   2693 C CA  . ALA B 1 55  ? -16.00020 28.87725 -69.91270 1.000 45.20199 ? 56  ALA B CA  1 
ATOM   2694 C C   . ALA B 1 55  ? -14.99901 28.07521 -69.10185 1.000 44.52646 ? 56  ALA B C   1 
ATOM   2695 O O   . ALA B 1 55  ? -14.45545 27.07369 -69.58433 1.000 44.21605 ? 56  ALA B O   1 
ATOM   2696 C CB  . ALA B 1 55  ? -15.32302 30.10190 -70.52132 1.000 43.19787 ? 56  ALA B CB  1 
ATOM   2697 N N   . LEU B 1 56  ? -14.73495 28.51175 -67.87051 1.000 44.36232 ? 57  LEU B N   1 
ATOM   2698 C CA  . LEU B 1 56  ? -13.78647 27.80254 -67.02425 1.000 40.77054 ? 57  LEU B CA  1 
ATOM   2699 C C   . LEU B 1 56  ? -14.22862 26.36469 -66.79293 1.000 38.46982 ? 57  LEU B C   1 
ATOM   2700 O O   . LEU B 1 56  ? -13.40091 25.44957 -66.80886 1.000 40.35283 ? 57  LEU B O   1 
ATOM   2701 C CB  . LEU B 1 56  ? -13.61584 28.55601 -65.70701 1.000 39.08738 ? 57  LEU B CB  1 
ATOM   2702 C CG  . LEU B 1 56  ? -12.68041 29.76022 -65.82347 1.000 40.70763 ? 57  LEU B CG  1 
ATOM   2703 C CD1 . LEU B 1 56  ? -12.85885 30.71780 -64.64663 1.000 39.46091 ? 57  LEU B CD1 1 
ATOM   2704 C CD2 . LEU B 1 56  ? -11.24122 29.29180 -65.91652 1.000 43.29606 ? 57  LEU B CD2 1 
ATOM   2705 N N   . LEU B 1 57  ? -15.53591 26.14532 -66.61057 1.000 36.25967 ? 58  LEU B N   1 
ATOM   2706 C CA  . LEU B 1 57  ? -16.06189 24.79527 -66.43042 1.000 38.47770 ? 58  LEU B CA  1 
ATOM   2707 C C   . LEU B 1 57  ? -15.80865 23.93365 -67.65970 1.000 43.82725 ? 58  LEU B C   1 
ATOM   2708 O O   . LEU B 1 57  ? -15.50577 22.73703 -67.54015 1.000 40.71077 ? 58  LEU B O   1 
ATOM   2709 C CB  . LEU B 1 57  ? -17.55955 24.85603 -66.14760 1.000 37.76594 ? 58  LEU B CB  1 
ATOM   2710 C CG  . LEU B 1 57  ? -18.25072 23.82330 -65.25600 1.000 39.55348 ? 58  LEU B CG  1 
ATOM   2711 C CD1 . LEU B 1 57  ? -19.55311 23.35762 -65.87511 1.000 41.84022 ? 58  LEU B CD1 1 
ATOM   2712 C CD2 . LEU B 1 57  ? -17.36546 22.64641 -64.89436 1.000 41.65339 ? 58  LEU B CD2 1 
ATOM   2713 N N   . ILE B 1 58  ? -15.97560 24.52195 -68.84955 1.000 42.71933 ? 59  ILE B N   1 
ATOM   2714 C CA  . ILE B 1 58  ? -15.74277 23.81049 -70.10531 1.000 45.90247 ? 59  ILE B CA  1 
ATOM   2715 C C   . ILE B 1 58  ? -14.28962 23.37254 -70.20554 1.000 39.13723 ? 59  ILE B C   1 
ATOM   2716 O O   . ILE B 1 58  ? -13.99103 22.23193 -70.58148 1.000 44.51180 ? 59  ILE B O   1 
ATOM   2717 C CB  . ILE B 1 58  ? -16.14310 24.70242 -71.29913 1.000 45.15727 ? 59  ILE B CB  1 
ATOM   2718 C CG1 . ILE B 1 58  ? -17.65267 24.96920 -71.29772 1.000 45.58453 ? 59  ILE B CG1 1 
ATOM   2719 C CG2 . ILE B 1 58  ? -15.68245 24.08338 -72.62112 1.000 47.71107 ? 59  ILE B CG2 1 
ATOM   2720 C CD1 . ILE B 1 58  ? -18.49384 23.71833 -71.39780 1.000 48.09996 ? 59  ILE B CD1 1 
ATOM   2721 N N   . SER B 1 59  ? -13.36479 24.27139 -69.86475 1.000 39.42474 ? 60  SER B N   1 
ATOM   2722 C CA  . SER B 1 59  ? -11.93876 23.99020 -69.94341 1.000 42.24651 ? 60  SER B CA  1 
ATOM   2723 C C   . SER B 1 59  ? -11.46306 22.97008 -68.91267 1.000 44.12368 ? 60  SER B C   1 
ATOM   2724 O O   . SER B 1 59  ? -10.33335 22.48418 -69.03538 1.000 43.42700 ? 60  SER B O   1 
ATOM   2725 C CB  . SER B 1 59  ? -11.15358 25.28869 -69.77438 1.000 41.96601 ? 60  SER B CB  1 
ATOM   2726 O OG  . SER B 1 59  ? -11.00980 25.61244 -68.40358 1.000 45.51407 ? 60  SER B OG  1 
ATOM   2727 N N   . MET B 1 60  ? -12.27322 22.64522 -67.90321 1.000 42.69982 ? 61  MET B N   1 
ATOM   2728 C CA  . MET B 1 60  ? -11.86172 21.66869 -66.90130 1.000 43.52976 ? 61  MET B CA  1 
ATOM   2729 C C   . MET B 1 60  ? -11.85256 20.27659 -67.51592 1.000 41.35906 ? 61  MET B C   1 
ATOM   2730 O O   . MET B 1 60  ? -12.65762 19.95972 -68.39443 1.000 40.14140 ? 61  MET B O   1 
ATOM   2731 C CB  . MET B 1 60  ? -12.80162 21.69478 -65.68719 1.000 42.26774 ? 61  MET B CB  1 
ATOM   2732 C CG  . MET B 1 60  ? -12.70150 22.95818 -64.80964 1.000 42.22516 ? 61  MET B CG  1 
ATOM   2733 S SD  . MET B 1 60  ? -11.01137 23.38007 -64.32479 1.000 48.77142 ? 61  MET B SD  1 
ATOM   2734 C CE  . MET B 1 60  ? -10.94737 25.13684 -64.67147 1.000 42.61585 ? 61  MET B CE  1 
ATOM   2735 N N   . THR B 1 61  ? -10.93572 19.43459 -67.04585 1.000 38.57674 ? 62  THR B N   1 
ATOM   2736 C CA  . THR B 1 61  ? -10.83615 18.08980 -67.58939 1.000 38.34643 ? 62  THR B CA  1 
ATOM   2737 C C   . THR B 1 61  ? -10.88229 17.06025 -66.46775 1.000 40.94508 ? 62  THR B C   1 
ATOM   2738 O O   . THR B 1 61  ? -11.07053 17.38901 -65.28868 1.000 37.47719 ? 62  THR B O   1 
ATOM   2739 C CB  . THR B 1 61  ? -9.56705  17.90976 -68.43027 1.000 40.67378 ? 62  THR B CB  1 
ATOM   2740 O OG1 . THR B 1 61  ? -9.36044  16.51116 -68.66540 1.000 51.11801 ? 62  THR B OG1 1 
ATOM   2741 C CG2 . THR B 1 61  ? -8.35480  18.47857 -67.71656 1.000 37.56151 ? 62  THR B CG2 1 
ATOM   2742 N N   . ASN B 1 62  ? -10.68262 15.79630 -66.87641 1.000 42.65768 ? 63  ASN B N   1 
ATOM   2743 C CA  . ASN B 1 62  ? -10.84485 14.64449 -65.99068 1.000 42.00887 ? 63  ASN B CA  1 
ATOM   2744 C C   . ASN B 1 62  ? -10.15397 14.84686 -64.64498 1.000 40.21957 ? 63  ASN B C   1 
ATOM   2745 O O   . ASN B 1 62  ? -10.68489 14.44943 -63.60345 1.000 34.99980 ? 63  ASN B O   1 
ATOM   2746 C CB  . ASN B 1 62  ? -10.29647 13.38142 -66.66708 1.000 41.63196 ? 63  ASN B CB  1 
ATOM   2747 C CG  . ASN B 1 62  ? -11.23477 12.81263 -67.72289 1.000 45.82009 ? 63  ASN B CG  1 
ATOM   2748 O OD1 . ASN B 1 62  ? -12.39355 13.21938 -67.83515 1.000 44.20504 ? 63  ASN B OD1 1 
ATOM   2749 N ND2 . ASN B 1 62  ? -10.73114 11.85635 -68.50265 1.000 43.96692 ? 63  ASN B ND2 1 
ATOM   2750 N N   . HIS B 1 63  ? -8.97214  15.46274 -64.65088 1.000 33.89096 ? 64  HIS B N   1 
ATOM   2751 C CA  . HIS B 1 63  ? -8.09602  15.51707 -63.48755 1.000 29.90590 ? 64  HIS B CA  1 
ATOM   2752 C C   . HIS B 1 63  ? -7.68714  16.94647 -63.16685 1.000 31.89310 ? 64  HIS B C   1 
ATOM   2753 O O   . HIS B 1 63  ? -6.62224  17.18362 -62.58987 1.000 31.48298 ? 64  HIS B O   1 
ATOM   2754 C CB  . HIS B 1 63  ? -6.86351  14.64003 -63.70690 1.000 32.30796 ? 64  HIS B CB  1 
ATOM   2755 C CG  . HIS B 1 63  ? -7.18861  13.19629 -63.94176 1.000 32.85254 ? 64  HIS B CG  1 
ATOM   2756 N ND1 . HIS B 1 63  ? -7.24047  12.63796 -65.20185 1.000 32.71613 ? 64  HIS B ND1 1 
ATOM   2757 C CD2 . HIS B 1 63  ? -7.49619  12.19945 -63.07542 1.000 33.52156 ? 64  HIS B CD2 1 
ATOM   2758 C CE1 . HIS B 1 63  ? -7.56006  11.35906 -65.10185 1.000 35.46547 ? 64  HIS B CE1 1 
ATOM   2759 N NE2 . HIS B 1 63  ? -7.72033  11.06696 -63.82259 1.000 37.42991 ? 64  HIS B NE2 1 
ATOM   2760 N N   . SER B 1 64  ? -8.52178  17.91057 -63.55663 1.000 32.20467 ? 65  SER B N   1 
ATOM   2761 C CA  . SER B 1 64  ? -8.29698  19.28850 -63.13930 1.000 32.69685 ? 65  SER B CA  1 
ATOM   2762 C C   . SER B 1 64  ? -8.45035  19.45258 -61.62931 1.000 29.80483 ? 65  SER B C   1 
ATOM   2763 O O   . SER B 1 64  ? -7.84258  20.35254 -61.04025 1.000 31.66978 ? 65  SER B O   1 
ATOM   2764 C CB  . SER B 1 64  ? -9.26442  20.21811 -63.87167 1.000 35.91437 ? 65  SER B CB  1 
ATOM   2765 O OG  . SER B 1 64  ? -8.89342  20.36902 -65.23283 1.000 37.96092 ? 65  SER B OG  1 
ATOM   2766 N N   . PHE B 1 65  ? -9.25005  18.60809 -60.98768 1.000 29.04300 ? 66  PHE B N   1 
ATOM   2767 C CA  . PHE B 1 65  ? -9.53409  18.74718 -59.56460 1.000 29.75801 ? 66  PHE B CA  1 
ATOM   2768 C C   . PHE B 1 65  ? -8.85933  17.64602 -58.76324 1.000 33.29324 ? 66  PHE B C   1 
ATOM   2769 O O   . PHE B 1 65  ? -8.94224  16.46828 -59.11788 1.000 34.53164 ? 66  PHE B O   1 
ATOM   2770 C CB  . PHE B 1 65  ? -11.04039 18.72357 -59.30557 1.000 24.24001 ? 66  PHE B CB  1 
ATOM   2771 C CG  . PHE B 1 65  ? -11.76703 19.83927 -59.97159 1.000 30.04916 ? 66  PHE B CG  1 
ATOM   2772 C CD1 . PHE B 1 65  ? -11.70320 21.12697 -59.45414 1.000 31.46993 ? 66  PHE B CD1 1 
ATOM   2773 C CD2 . PHE B 1 65  ? -12.48422 19.61852 -61.14153 1.000 34.35330 ? 66  PHE B CD2 1 
ATOM   2774 C CE1 . PHE B 1 65  ? -12.36848 22.16671 -60.07863 1.000 33.35948 ? 66  PHE B CE1 1 
ATOM   2775 C CE2 . PHE B 1 65  ? -13.15259 20.65245 -61.76892 1.000 33.73294 ? 66  PHE B CE2 1 
ATOM   2776 C CZ  . PHE B 1 65  ? -13.09317 21.92920 -61.23796 1.000 32.20733 ? 66  PHE B CZ  1 
ATOM   2777 N N   . SER B 1 66  ? -8.20646  18.04102 -57.67423 1.000 33.58704 ? 67  SER B N   1 
ATOM   2778 C CA  . SER B 1 66  ? -7.64704  17.11939 -56.69570 1.000 31.59911 ? 67  SER B CA  1 
ATOM   2779 C C   . SER B 1 66  ? -8.35597  17.31531 -55.35773 1.000 31.04931 ? 67  SER B C   1 
ATOM   2780 O O   . SER B 1 66  ? -8.42969  18.43886 -54.84752 1.000 30.91917 ? 67  SER B O   1 
ATOM   2781 C CB  . SER B 1 66  ? -6.14570  17.34559 -56.53398 1.000 29.47345 ? 67  SER B CB  1 
ATOM   2782 O OG  . SER B 1 66  ? -5.57646  16.32387 -55.72539 1.000 42.16769 ? 67  SER B OG  1 
ATOM   2783 N N   . VAL B 1 67  ? -8.85875  16.23096 -54.78252 1.000 25.74800 ? 68  VAL B N   1 
ATOM   2784 C CA  . VAL B 1 67  ? -9.55641  16.28101 -53.50085 1.000 29.74341 ? 68  VAL B CA  1 
ATOM   2785 C C   . VAL B 1 67  ? -8.80717  15.40505 -52.50875 1.000 32.73279 ? 68  VAL B C   1 
ATOM   2786 O O   . VAL B 1 67  ? -8.54072  14.23056 -52.79122 1.000 29.02747 ? 68  VAL B O   1 
ATOM   2787 C CB  . VAL B 1 67  ? -11.02152 15.82851 -53.62712 1.000 26.22248 ? 68  VAL B CB  1 
ATOM   2788 C CG1 . VAL B 1 67  ? -11.69259 15.84873 -52.26163 1.000 26.65749 ? 68  VAL B CG1 1 
ATOM   2789 C CG2 . VAL B 1 67  ? -11.76675 16.71111 -54.64070 1.000 22.72467 ? 68  VAL B CG2 1 
ATOM   2790 N N   . GLN B 1 68  ? -8.48673  15.96800 -51.34349 1.000 27.58665 ? 69  GLN B N   1 
ATOM   2791 C CA  . GLN B 1 68  ? -7.76214  15.25011 -50.30394 1.000 31.10041 ? 69  GLN B CA  1 
ATOM   2792 C C   . GLN B 1 68  ? -8.53594  15.27324 -48.99062 1.000 34.69194 ? 69  GLN B C   1 
ATOM   2793 O O   . GLN B 1 68  ? -8.99899  16.33292 -48.54511 1.000 27.16333 ? 69  GLN B O   1 
ATOM   2794 C CB  . GLN B 1 68  ? -6.35819  15.83732 -50.09871 1.000 35.92264 ? 69  GLN B CB  1 
ATOM   2795 C CG  . GLN B 1 68  ? -5.56977  15.14250 -48.97743 1.000 41.20219 ? 69  GLN B CG  1 
ATOM   2796 C CD  . GLN B 1 68  ? -5.01542  13.76974 -49.37956 1.000 48.17593 ? 69  GLN B CD  1 
ATOM   2797 O OE1 . GLN B 1 68  ? -4.97659  13.42129 -50.56654 1.000 45.64677 ? 69  GLN B OE1 1 
ATOM   2798 N NE2 . GLN B 1 68  ? -4.59101  12.98304 -48.38259 1.000 50.96208 ? 69  GLN B NE2 1 
ATOM   2799 N N   . LYS B 1 69  ? -8.66751  14.09766 -48.37661 1.000 32.31521 ? 70  LYS B N   1 
ATOM   2800 C CA  . LYS B 1 69  ? -9.20948  13.94597 -47.03649 1.000 34.93640 ? 70  LYS B CA  1 
ATOM   2801 C C   . LYS B 1 69  ? -8.03576  13.84616 -46.06555 1.000 40.77023 ? 70  LYS B C   1 
ATOM   2802 O O   . LYS B 1 69  ? -7.18636  12.96143 -46.21126 1.000 43.01657 ? 70  LYS B O   1 
ATOM   2803 C CB  . LYS B 1 69  ? -10.09477 12.70226 -46.96028 1.000 38.20193 ? 70  LYS B CB  1 
ATOM   2804 C CG  . LYS B 1 69  ? -10.64951 12.40941 -45.58161 1.000 39.15141 ? 70  LYS B CG  1 
ATOM   2805 C CD  . LYS B 1 69  ? -12.04477 12.98245 -45.44265 1.000 41.99602 ? 70  LYS B CD  1 
ATOM   2806 C CE  . LYS B 1 69  ? -12.45700 13.14483 -43.98825 1.000 46.12881 ? 70  LYS B CE  1 
ATOM   2807 N NZ  . LYS B 1 69  ? -13.70764 13.96047 -43.87055 1.000 39.04536 ? 70  LYS B NZ  1 
ATOM   2808 N N   . HIS B 1 70  ? -7.97633  14.76161 -45.09382 1.000 41.19020 ? 71  HIS B N   1 
ATOM   2809 C CA  . HIS B 1 70  ? -6.88207  14.80386 -44.12611 1.000 42.84242 ? 71  HIS B CA  1 
ATOM   2810 C C   . HIS B 1 70  ? -7.24844  14.23923 -42.76615 1.000 50.60136 ? 71  HIS B C   1 
ATOM   2811 O O   . HIS B 1 70  ? -6.35074  13.85073 -42.00954 1.000 50.87147 ? 71  HIS B O   1 
ATOM   2812 C CB  . HIS B 1 70  ? -6.40486  16.23796 -43.90803 1.000 40.45375 ? 71  HIS B CB  1 
ATOM   2813 C CG  . HIS B 1 70  ? -5.89785  16.90474 -45.14331 1.000 42.30645 ? 71  HIS B CG  1 
ATOM   2814 N ND1 . HIS B 1 70  ? -4.73652  16.51861 -45.77565 1.000 43.24075 ? 71  HIS B ND1 1 
ATOM   2815 C CD2 . HIS B 1 70  ? -6.38763  17.94513 -45.85752 1.000 39.69160 ? 71  HIS B CD2 1 
ATOM   2816 C CE1 . HIS B 1 70  ? -4.52712  17.29641 -46.82346 1.000 42.79706 ? 71  HIS B CE1 1 
ATOM   2817 N NE2 . HIS B 1 70  ? -5.51780  18.16682 -46.89907 1.000 41.21186 ? 71  HIS B NE2 1 
ATOM   2818 N N   . ILE B 1 71  ? -8.53126  14.20922 -42.44474 1.000 50.77571 ? 72  ILE B N   1 
ATOM   2819 C CA  . ILE B 1 71  ? -9.03295  13.87750 -41.12052 1.000 54.69002 ? 72  ILE B CA  1 
ATOM   2820 C C   . ILE B 1 71  ? -9.54645  12.44516 -41.16252 1.000 58.71437 ? 72  ILE B C   1 
ATOM   2821 O O   . ILE B 1 71  ? -10.21316 12.03666 -42.12573 1.000 58.37494 ? 72  ILE B O   1 
ATOM   2822 C CB  . ILE B 1 71  ? -10.12561 14.88704 -40.69865 1.000 54.62352 ? 72  ILE B CB  1 
ATOM   2823 C CG1 . ILE B 1 71  ? -9.50979  16.05241 -39.90385 1.000 53.52522 ? 72  ILE B CG1 1 
ATOM   2824 C CG2 . ILE B 1 71  ? -11.25782 14.20833 -39.92580 1.000 55.10018 ? 72  ILE B CG2 1 
ATOM   2825 C CD1 . ILE B 1 71  ? -8.52931  16.92770 -40.70658 1.000 44.40932 ? 72  ILE B CD1 1 
ATOM   2826 N N   . GLY B 1 72  ? -9.21781  11.67019 -40.13119 1.000 61.01509 ? 73  GLY B N   1 
ATOM   2827 C CA  . GLY B 1 72  ? -9.41205  10.23637 -40.21227 1.000 63.28947 ? 73  GLY B CA  1 
ATOM   2828 C C   . GLY B 1 72  ? -8.25554  9.58872  -40.95600 1.000 66.64413 ? 73  GLY B C   1 
ATOM   2829 O O   . GLY B 1 72  ? -7.11485  10.05885 -40.90827 1.000 66.83874 ? 73  GLY B O   1 
ATOM   2830 N N   . ALA B 1 73  ? -8.55758  8.49792  -41.65142 1.000 68.33177 ? 74  ALA B N   1 
ATOM   2831 C CA  . ALA B 1 73  ? -7.56161  7.86301  -42.51312 1.000 69.15418 ? 74  ALA B CA  1 
ATOM   2832 C C   . ALA B 1 73  ? -7.37585  8.70862  -43.76397 1.000 69.26446 ? 74  ALA B C   1 
ATOM   2833 O O   . ALA B 1 73  ? -8.31835  8.82760  -44.56417 1.000 66.46005 ? 74  ALA B O   1 
ATOM   2834 C CB  . ALA B 1 73  ? -7.98368  6.44732  -42.88909 1.000 68.09936 ? 74  ALA B CB  1 
ATOM   2835 N N   . PRO B 1 74  ? -6.20501  9.31272  -43.97844 1.000 65.53819 ? 75  PRO B N   1 
ATOM   2836 C CA  . PRO B 1 74  ? -6.04218  10.21502 -45.12357 1.000 63.64636 ? 75  PRO B CA  1 
ATOM   2837 C C   . PRO B 1 74  ? -6.15374  9.46636  -46.44496 1.000 63.64618 ? 75  PRO B C   1 
ATOM   2838 O O   . PRO B 1 74  ? -5.79711  8.28951  -46.55575 1.000 64.49430 ? 75  PRO B O   1 
ATOM   2839 C CB  . PRO B 1 74  ? -4.63697  10.80876 -44.92773 1.000 62.24967 ? 75  PRO B CB  1 
ATOM   2840 C CG  . PRO B 1 74  ? -4.20677  10.40206 -43.53403 1.000 65.68870 ? 75  PRO B CG  1 
ATOM   2841 C CD  . PRO B 1 74  ? -4.95385  9.14842  -43.21853 1.000 65.07391 ? 75  PRO B CD  1 
ATOM   2842 N N   . ALA B 1 75  ? -6.66583  10.16830 -47.45398 1.000 55.77400 ? 76  ALA B N   1 
ATOM   2843 C CA  . ALA B 1 75  ? -6.91198  9.55525  -48.74982 1.000 50.99219 ? 76  ALA B CA  1 
ATOM   2844 C C   . ALA B 1 75  ? -7.03056  10.64232 -49.80835 1.000 49.21641 ? 76  ALA B C   1 
ATOM   2845 O O   . ALA B 1 75  ? -7.51139  11.74674 -49.53464 1.000 38.55199 ? 76  ALA B O   1 
ATOM   2846 C CB  . ALA B 1 75  ? -8.18149  8.69195  -48.72810 1.000 46.92677 ? 76  ALA B CB  1 
ATOM   2847 N N   . ASN B 1 76  ? -6.55458  10.32107 -51.01129 1.000 45.25364 ? 77  ASN B N   1 
ATOM   2848 C CA  . ASN B 1 76  ? -6.95041  11.04697 -52.20914 1.000 42.31729 ? 77  ASN B CA  1 
ATOM   2849 C C   . ASN B 1 76  ? -8.29106  10.48821 -52.68192 1.000 41.72073 ? 77  ASN B C   1 
ATOM   2850 O O   . ASN B 1 76  ? -8.49798  9.26842  -52.69771 1.000 39.02488 ? 77  ASN B O   1 
ATOM   2851 C CB  . ASN B 1 76  ? -5.87528  10.91379 -53.29639 1.000 44.15977 ? 77  ASN B CB  1 
ATOM   2852 C CG  . ASN B 1 76  ? -6.31662  11.47269 -54.65312 1.000 47.84800 ? 77  ASN B CG  1 
ATOM   2853 O OD1 . ASN B 1 76  ? -6.56659  12.67483 -54.79256 1.000 46.82671 ? 77  ASN B OD1 1 
ATOM   2854 N ND2 . ASN B 1 76  ? -6.38238  10.60350 -55.66756 1.000 47.41430 ? 77  ASN B ND2 1 
ATOM   2855 N N   . LEU B 1 77  ? -9.21707  11.37687 -53.01931 1.000 37.32636 ? 78  LEU B N   1 
ATOM   2856 C CA  . LEU B 1 77  ? -10.51944 10.99571 -53.55624 1.000 35.48786 ? 78  LEU B CA  1 
ATOM   2857 C C   . LEU B 1 77  ? -10.55415 11.35852 -55.03518 1.000 35.69042 ? 78  LEU B C   1 
ATOM   2858 O O   . LEU B 1 77  ? -10.47076 12.54015 -55.38696 1.000 36.22340 ? 78  LEU B O   1 
ATOM   2859 C CB  . LEU B 1 77  ? -11.65041 11.70344 -52.81041 1.000 31.90911 ? 78  LEU B CB  1 
ATOM   2860 C CG  . LEU B 1 77  ? -11.79294 11.48615 -51.30649 1.000 36.59869 ? 78  LEU B CG  1 
ATOM   2861 C CD1 . LEU B 1 77  ? -12.89991 12.39383 -50.74990 1.000 29.67964 ? 78  LEU B CD1 1 
ATOM   2862 C CD2 . LEU B 1 77  ? -12.08856 10.01453 -51.02363 1.000 39.03534 ? 78  LEU B CD2 1 
ATOM   2863 N N   . ARG B 1 78  ? -10.68357 10.35339 -55.89327 1.000 31.73866 ? 79  ARG B N   1 
ATOM   2864 C CA  . ARG B 1 78  ? -10.65852 10.59047 -57.33111 1.000 35.28400 ? 79  ARG B CA  1 
ATOM   2865 C C   . ARG B 1 78  ? -11.94347 11.27297 -57.78393 1.000 28.12430 ? 79  ARG B C   1 
ATOM   2866 O O   . ARG B 1 78  ? -13.04577 10.81241 -57.48244 1.000 34.66430 ? 79  ARG B O   1 
ATOM   2867 C CB  . ARG B 1 78  ? -10.48103 9.27318  -58.08669 1.000 37.71625 ? 79  ARG B CB  1 
ATOM   2868 C CG  . ARG B 1 78  ? -9.11439  9.07228  -58.71420 1.000 45.38179 ? 79  ARG B CG  1 
ATOM   2869 C CD  . ARG B 1 78  ? -9.04071  7.74855  -59.49004 1.000 40.38638 ? 79  ARG B CD  1 
ATOM   2870 N NE  . ARG B 1 78  ? -10.02369 7.65233  -60.57916 1.000 48.46541 ? 79  ARG B NE  1 
ATOM   2871 C CZ  . ARG B 1 78  ? -9.83862  8.11186  -61.82090 1.000 48.06665 ? 79  ARG B CZ  1 
ATOM   2872 N NH1 . ARG B 1 78  ? -8.70283  8.72340  -62.15917 1.000 47.54224 ? 79  ARG B NH1 1 
ATOM   2873 N NH2 . ARG B 1 78  ? -10.78841 7.95745  -62.73538 1.000 47.44645 ? 79  ARG B NH2 1 
ATOM   2874 N N   . VAL B 1 79  ? -11.79478 12.36104 -58.52511 1.000 26.41739 ? 80  VAL B N   1 
ATOM   2875 C CA  . VAL B 1 79  ? -12.93308 13.07150 -59.09873 1.000 27.90145 ? 80  VAL B CA  1 
ATOM   2876 C C   . VAL B 1 79  ? -13.33718 12.38532 -60.40387 1.000 30.51277 ? 80  VAL B C   1 
ATOM   2877 O O   . VAL B 1 79  ? -12.49827 12.15849 -61.27575 1.000 29.72968 ? 80  VAL B O   1 
ATOM   2878 C CB  . VAL B 1 79  ? -12.57535 14.55167 -59.31038 1.000 27.34284 ? 80  VAL B CB  1 
ATOM   2879 C CG1 . VAL B 1 79  ? -13.63362 15.26281 -60.10197 1.000 25.52175 ? 80  VAL B CG1 1 
ATOM   2880 C CG2 . VAL B 1 79  ? -12.38803 15.22952 -57.94059 1.000 27.80906 ? 80  VAL B CG2 1 
ATOM   2881 N N   . VAL B 1 80  ? -14.62084 12.04907 -60.53872 1.000 28.20618 ? 81  VAL B N   1 
ATOM   2882 C CA  . VAL B 1 80  ? -15.11993 11.34234 -61.71536 1.000 28.96860 ? 81  VAL B CA  1 
ATOM   2883 C C   . VAL B 1 80  ? -16.13876 12.13621 -62.51525 1.000 32.36422 ? 81  VAL B C   1 
ATOM   2884 O O   . VAL B 1 80  ? -16.55024 11.67448 -63.58962 1.000 33.33979 ? 81  VAL B O   1 
ATOM   2885 C CB  . VAL B 1 80  ? -15.71964 9.97453  -61.33880 1.000 30.63788 ? 81  VAL B CB  1 
ATOM   2886 C CG1 . VAL B 1 80  ? -14.64116 9.06430  -60.77631 1.000 34.25267 ? 81  VAL B CG1 1 
ATOM   2887 C CG2 . VAL B 1 80  ? -16.85235 10.17061 -60.35526 1.000 33.20535 ? 81  VAL B CG2 1 
ATOM   2888 N N   . GLY B 1 81  ? -16.57897 13.28854 -62.03612 1.000 28.28898 ? 82  GLY B N   1 
ATOM   2889 C CA  . GLY B 1 81  ? -17.36774 14.19575 -62.84536 1.000 31.39060 ? 82  GLY B CA  1 
ATOM   2890 C C   . GLY B 1 81  ? -17.39337 15.54832 -62.17828 1.000 32.81450 ? 82  GLY B C   1 
ATOM   2891 O O   . GLY B 1 81  ? -17.11281 15.66857 -60.98283 1.000 29.60788 ? 82  GLY B O   1 
ATOM   2892 N N   . HIS B 1 82  ? -17.70952 16.57394 -62.96502 1.000 31.40288 ? 83  HIS B N   1 
ATOM   2893 C CA  . HIS B 1 82  ? -17.79843 17.91260 -62.39505 1.000 31.44607 ? 83  HIS B CA  1 
ATOM   2894 C C   . HIS B 1 82  ? -18.98104 18.66658 -62.97833 1.000 37.60546 ? 83  HIS B C   1 
ATOM   2895 O O   . HIS B 1 82  ? -19.20882 18.63172 -64.18882 1.000 38.41251 ? 83  HIS B O   1 
ATOM   2896 C CB  . HIS B 1 82  ? -16.49768 18.69894 -62.59826 1.000 34.68857 ? 83  HIS B CB  1 
ATOM   2897 C CG  . HIS B 1 82  ? -15.95421 18.65577 -63.99283 1.000 38.97009 ? 83  HIS B CG  1 
ATOM   2898 N ND1 . HIS B 1 82  ? -16.40305 19.48937 -64.99460 1.000 46.40685 ? 83  HIS B ND1 1 
ATOM   2899 C CD2 . HIS B 1 82  ? -14.96933 17.90824 -64.54045 1.000 39.17149 ? 83  HIS B CD2 1 
ATOM   2900 C CE1 . HIS B 1 82  ? -15.73068 19.24396 -66.10498 1.000 42.49140 ? 83  HIS B CE1 1 
ATOM   2901 N NE2 . HIS B 1 82  ? -14.85559 18.28748 -65.85613 1.000 43.20074 ? 83  HIS B NE2 1 
ATOM   2902 N N   . ALA B 1 83  ? -19.73747 19.33434 -62.10807 1.000 35.19072 ? 84  ALA B N   1 
ATOM   2903 C CA  . ALA B 1 83  ? -20.86926 20.15875 -62.50710 1.000 32.99975 ? 84  ALA B CA  1 
ATOM   2904 C C   . ALA B 1 83  ? -20.83504 21.47980 -61.75064 1.000 38.11817 ? 84  ALA B C   1 
ATOM   2905 O O   . ALA B 1 83  ? -20.16003 21.62370 -60.72352 1.000 29.90924 ? 84  ALA B O   1 
ATOM   2906 C CB  . ALA B 1 83  ? -22.20933 19.45952 -62.24668 1.000 29.19801 ? 84  ALA B CB  1 
ATOM   2907 N N   . MET B 1 84  ? -21.57687 22.45147 -62.27009 1.000 35.68102 ? 85  MET B N   1 
ATOM   2908 C CA  . MET B 1 84  ? -21.70217 23.74931 -61.62702 1.000 33.01486 ? 85  MET B CA  1 
ATOM   2909 C C   . MET B 1 84  ? -23.16351 23.99088 -61.29492 1.000 37.16445 ? 85  MET B C   1 
ATOM   2910 O O   . MET B 1 84  ? -24.05237 23.68399 -62.09706 1.000 37.11174 ? 85  MET B O   1 
ATOM   2911 C CB  . MET B 1 84  ? -21.15897 24.87158 -62.50656 1.000 36.63342 ? 85  MET B CB  1 
ATOM   2912 C CG  . MET B 1 84  ? -21.28573 26.24104 -61.86366 1.000 35.44104 ? 85  MET B CG  1 
ATOM   2913 S SD  . MET B 1 84  ? -20.39159 27.54354 -62.70379 1.000 41.64160 ? 85  MET B SD  1 
ATOM   2914 C CE  . MET B 1 84  ? -18.74250 26.92001 -62.68210 1.000 38.67196 ? 85  MET B CE  1 
ATOM   2915 N N   . GLN B 1 85  ? -23.40567 24.52157 -60.09923 1.000 32.55404 ? 86  GLN B N   1 
ATOM   2916 C CA  . GLN B 1 85  ? -24.74690 24.88865 -59.65938 1.000 34.57350 ? 86  GLN B CA  1 
ATOM   2917 C C   . GLN B 1 85  ? -24.62959 26.24721 -58.97671 1.000 33.88558 ? 86  GLN B C   1 
ATOM   2918 O O   . GLN B 1 85  ? -24.14597 26.34164 -57.84439 1.000 32.35016 ? 86  GLN B O   1 
ATOM   2919 C CB  . GLN B 1 85  ? -25.31643 23.82773 -58.73399 1.000 35.17081 ? 86  GLN B CB  1 
ATOM   2920 C CG  . GLN B 1 85  ? -26.64939 24.16036 -58.12042 1.000 36.51446 ? 86  GLN B CG  1 
ATOM   2921 C CD  . GLN B 1 85  ? -27.28004 22.93885 -57.51143 1.000 42.93667 ? 86  GLN B CD  1 
ATOM   2922 O OE1 . GLN B 1 85  ? -26.93075 21.81025 -57.86228 1.000 45.97980 ? 86  GLN B OE1 1 
ATOM   2923 N NE2 . GLN B 1 85  ? -28.22064 23.14725 -56.59762 1.000 43.27464 ? 86  GLN B NE2 1 
ATOM   2924 N N   . GLY B 1 86  ? -25.03646 27.29994 -59.68041 1.000 34.51185 ? 87  GLY B N   1 
ATOM   2925 C CA  . GLY B 1 86  ? -24.86668 28.64086 -59.14017 1.000 32.74429 ? 87  GLY B CA  1 
ATOM   2926 C C   . GLY B 1 86  ? -23.39907 28.95976 -58.94720 1.000 33.42679 ? 87  GLY B C   1 
ATOM   2927 O O   . GLY B 1 86  ? -22.57597 28.80185 -59.86045 1.000 30.64605 ? 87  GLY B O   1 
ATOM   2928 N N   . THR B 1 87  ? -23.05286 29.39819 -57.73200 1.000 27.54526 ? 88  THR B N   1 
ATOM   2929 C CA  . THR B 1 87  ? -21.68839 29.77952 -57.38920 1.000 27.25743 ? 88  THR B CA  1 
ATOM   2930 C C   . THR B 1 87  ? -20.89061 28.63365 -56.76367 1.000 26.95000 ? 88  THR B C   1 
ATOM   2931 O O   . THR B 1 87  ? -19.80031 28.87680 -56.23523 1.000 25.14674 ? 88  THR B O   1 
ATOM   2932 C CB  . THR B 1 87  ? -21.70366 30.96255 -56.41842 1.000 27.64693 ? 88  THR B CB  1 
ATOM   2933 O OG1 . THR B 1 87  ? -22.51142 30.60861 -55.29050 1.000 27.04977 ? 88  THR B OG1 1 
ATOM   2934 C CG2 . THR B 1 87  ? -22.29585 32.22376 -57.08482 1.000 26.76815 ? 88  THR B CG2 1 
ATOM   2935 N N   . LEU B 1 88  ? -21.41840 27.41271 -56.79458 1.000 26.84684 ? 89  LEU B N   1 
ATOM   2936 C CA  . LEU B 1 88  ? -20.77878 26.22709 -56.23386 1.000 28.89045 ? 89  LEU B CA  1 
ATOM   2937 C C   . LEU B 1 88  ? -20.47889 25.20354 -57.32370 1.000 30.85841 ? 89  LEU B C   1 
ATOM   2938 O O   . LEU B 1 88  ? -21.21780 25.08501 -58.30965 1.000 30.45779 ? 89  LEU B O   1 
ATOM   2939 C CB  . LEU B 1 88  ? -21.67180 25.55040 -55.18941 1.000 24.22838 ? 89  LEU B CB  1 
ATOM   2940 C CG  . LEU B 1 88  ? -22.08693 26.38630 -53.98274 1.000 27.28605 ? 89  LEU B CG  1 
ATOM   2941 C CD1 . LEU B 1 88  ? -23.07877 25.58857 -53.15745 1.000 27.25096 ? 89  LEU B CD1 1 
ATOM   2942 C CD2 . LEU B 1 88  ? -20.85291 26.73795 -53.17974 1.000 27.62489 ? 89  LEU B CD2 1 
ATOM   2943 N N   . LEU B 1 89  ? -19.41176 24.43471 -57.11615 1.000 29.39801 ? 90  LEU B N   1 
ATOM   2944 C CA  . LEU B 1 89  ? -19.14682 23.24185 -57.90577 1.000 29.21841 ? 90  LEU B CA  1 
ATOM   2945 C C   . LEU B 1 89  ? -19.65798 22.01420 -57.16997 1.000 33.47359 ? 90  LEU B C   1 
ATOM   2946 O O   . LEU B 1 89  ? -19.67296 21.95441 -55.93595 1.000 30.20557 ? 90  LEU B O   1 
ATOM   2947 C CB  . LEU B 1 89  ? -17.65578 23.06406 -58.19804 1.000 28.09697 ? 90  LEU B CB  1 
ATOM   2948 C CG  . LEU B 1 89  ? -16.94393 24.18257 -58.92251 1.000 31.47682 ? 90  LEU B CG  1 
ATOM   2949 C CD1 . LEU B 1 89  ? -15.48568 23.81643 -59.12313 1.000 33.32826 ? 90  LEU B CD1 1 
ATOM   2950 C CD2 . LEU B 1 89  ? -17.62324 24.45731 -60.24438 1.000 36.67830 ? 90  LEU B CD2 1 
ATOM   2951 N N   . LYS B 1 90  ? -20.08774 21.03640 -57.94708 1.000 29.31711 ? 91  LYS B N   1 
ATOM   2952 C CA  . LYS B 1 90  ? -20.58575 19.76900 -57.44765 1.000 27.02252 ? 91  LYS B CA  1 
ATOM   2953 C C   . LYS B 1 90  ? -19.67760 18.75155 -58.12163 1.000 31.35268 ? 91  LYS B C   1 
ATOM   2954 O O   . LYS B 1 90  ? -19.78202 18.52876 -59.33325 1.000 30.99126 ? 91  LYS B O   1 
ATOM   2955 C CB  . LYS B 1 90  ? -22.05917 19.60392 -57.80053 1.000 29.82192 ? 91  LYS B CB  1 
ATOM   2956 C CG  . LYS B 1 90  ? -22.76399 18.37878 -57.28278 1.000 35.66316 ? 91  LYS B CG  1 
ATOM   2957 C CD  . LYS B 1 90  ? -24.21765 18.36353 -57.78296 1.000 38.97213 ? 91  LYS B CD  1 
ATOM   2958 C CE  . LYS B 1 90  ? -25.11520 17.53460 -56.88416 1.000 39.40408 ? 91  LYS B CE  1 
ATOM   2959 N NZ  . LYS B 1 90  ? -26.29719 17.00172 -57.63437 1.000 40.28658 ? 91  LYS B NZ  1 
ATOM   2960 N N   . LEU B 1 91  ? -18.73109 18.21198 -57.35946 1.000 30.05915 ? 92  LEU B N   1 
ATOM   2961 C CA  . LEU B 1 91  ? -17.75453 17.25772 -57.86586 1.000 28.79929 ? 92  LEU B CA  1 
ATOM   2962 C C   . LEU B 1 91  ? -18.19282 15.85471 -57.47617 1.000 27.88402 ? 92  LEU B C   1 
ATOM   2963 O O   . LEU B 1 91  ? -18.51244 15.60004 -56.31437 1.000 31.73093 ? 92  LEU B O   1 
ATOM   2964 C CB  . LEU B 1 91  ? -16.35794 17.55417 -57.30527 1.000 27.61247 ? 92  LEU B CB  1 
ATOM   2965 C CG  . LEU B 1 91  ? -15.77351 18.95058 -57.49925 1.000 28.46400 ? 92  LEU B CG  1 
ATOM   2966 C CD1 . LEU B 1 91  ? -14.36170 19.02114 -56.91397 1.000 25.07467 ? 92  LEU B CD1 1 
ATOM   2967 C CD2 . LEU B 1 91  ? -15.76188 19.36594 -58.96819 1.000 28.95814 ? 92  LEU B CD2 1 
ATOM   2968 N N   . THR B 1 92  ? -18.23735 14.95033 -58.44425 1.000 28.27056 ? 93  THR B N   1 
ATOM   2969 C CA  . THR B 1 92  ? -18.54493 13.56075 -58.14167 1.000 27.13483 ? 93  THR B CA  1 
ATOM   2970 C C   . THR B 1 92  ? -17.23860 12.82479 -57.91551 1.000 23.87718 ? 93  THR B C   1 
ATOM   2971 O O   . THR B 1 92  ? -16.31021 12.95340 -58.71642 1.000 25.14937 ? 93  THR B O   1 
ATOM   2972 C CB  . THR B 1 92  ? -19.33188 12.91063 -59.28043 1.000 28.68994 ? 93  THR B CB  1 
ATOM   2973 O OG1 . THR B 1 92  ? -20.43168 13.75699 -59.63443 1.000 28.70760 ? 93  THR B OG1 1 
ATOM   2974 C CG2 . THR B 1 92  ? -19.84707 11.56934 -58.83677 1.000 28.77376 ? 93  THR B CG2 1 
ATOM   2975 N N   . VAL B 1 93  ? -17.16449 12.06438 -56.82344 1.000 30.07398 ? 94  VAL B N   1 
ATOM   2976 C CA  . VAL B 1 93  ? -15.96294 11.31020 -56.49220 1.000 31.46578 ? 94  VAL B CA  1 
ATOM   2977 C C   . VAL B 1 93  ? -16.31444 9.83160  -56.43813 1.000 28.92713 ? 94  VAL B C   1 
ATOM   2978 O O   . VAL B 1 93  ? -17.46633 9.44851  -56.23393 1.000 30.82065 ? 94  VAL B O   1 
ATOM   2979 C CB  . VAL B 1 93  ? -15.31944 11.77692 -55.16751 1.000 28.35228 ? 94  VAL B CB  1 
ATOM   2980 C CG1 . VAL B 1 93  ? -14.83107 13.20304 -55.31097 1.000 26.64480 ? 94  VAL B CG1 1 
ATOM   2981 C CG2 . VAL B 1 93  ? -16.30701 11.65808 -54.00834 1.000 30.96952 ? 94  VAL B CG2 1 
ATOM   2982 N N   . ASP B 1 94  ? -15.30252 8.98822  -56.61615 1.000 33.41061 ? 95  ASP B N   1 
ATOM   2983 C CA  . ASP B 1 94  ? -15.61884 7.57137  -56.78330 1.000 33.04100 ? 95  ASP B CA  1 
ATOM   2984 C C   . ASP B 1 94  ? -15.79129 6.83162  -55.46302 1.000 35.30556 ? 95  ASP B C   1 
ATOM   2985 O O   . ASP B 1 94  ? -16.06095 5.62862  -55.48514 1.000 38.31997 ? 95  ASP B O   1 
ATOM   2986 C CB  . ASP B 1 94  ? -14.55669 6.86865  -57.65312 1.000 35.94601 ? 95  ASP B CB  1 
ATOM   2987 C CG  . ASP B 1 94  ? -13.15479 6.92364  -57.06124 1.000 41.95712 ? 95  ASP B CG  1 
ATOM   2988 O OD1 . ASP B 1 94  ? -12.96126 7.55305  -55.99752 1.000 40.43039 ? 95  ASP B OD1 1 
ATOM   2989 O OD2 . ASP B 1 94  ? -12.23525 6.32142  -57.66991 1.000 44.81416 ? 95  ASP B OD2 1 
ATOM   2990 N N   . VAL B 1 95  ? -15.68308 7.51137  -54.32081 1.000 33.60295 ? 96  VAL B N   1 
ATOM   2991 C CA  . VAL B 1 95  ? -15.86778 6.88980  -53.01210 1.000 32.99486 ? 96  VAL B CA  1 
ATOM   2992 C C   . VAL B 1 95  ? -16.88967 7.70501  -52.23746 1.000 34.03471 ? 96  VAL B C   1 
ATOM   2993 O O   . VAL B 1 95  ? -16.79500 8.93839  -52.19301 1.000 32.31528 ? 96  VAL B O   1 
ATOM   2994 C CB  . VAL B 1 95  ? -14.54619 6.80008  -52.22784 1.000 33.75081 ? 96  VAL B CB  1 
ATOM   2995 C CG1 . VAL B 1 95  ? -14.79231 6.20993  -50.83492 1.000 37.86009 ? 96  VAL B CG1 1 
ATOM   2996 C CG2 . VAL B 1 95  ? -13.54052 5.95750  -52.99285 1.000 38.25158 ? 96  VAL B CG2 1 
ATOM   2997 N N   . ALA B 1 96  ? -17.87031 7.02573  -51.64972 1.000 28.01113 ? 97  ALA B N   1 
ATOM   2998 C CA  . ALA B 1 96  ? -18.90903 7.69944  -50.88057 1.000 30.69541 ? 97  ALA B CA  1 
ATOM   2999 C C   . ALA B 1 96  ? -18.46223 7.88972  -49.43552 1.000 32.98329 ? 97  ALA B C   1 
ATOM   3000 O O   . ALA B 1 96  ? -17.86187 6.99586  -48.82990 1.000 28.23150 ? 97  ALA B O   1 
ATOM   3001 C CB  . ALA B 1 96  ? -20.21798 6.91159  -50.91547 1.000 31.15899 ? 97  ALA B CB  1 
ATOM   3002 N N   . ASN B 1 97  ? -18.76321 9.06259  -48.88303 1.000 27.00512 ? 98  ASN B N   1 
ATOM   3003 C CA  . ASN B 1 97  ? -18.39038 9.35411  -47.50789 1.000 26.78638 ? 98  ASN B CA  1 
ATOM   3004 C C   . ASN B 1 97  ? -19.04674 8.33929  -46.58506 1.000 24.95892 ? 98  ASN B C   1 
ATOM   3005 O O   . ASN B 1 97  ? -20.27384 8.34997  -46.43284 1.000 27.41149 ? 98  ASN B O   1 
ATOM   3006 C CB  . ASN B 1 97  ? -18.80287 10.78696 -47.14941 1.000 25.01303 ? 98  ASN B CB  1 
ATOM   3007 C CG  . ASN B 1 97  ? -18.30447 11.22271 -45.79152 1.000 30.39374 ? 98  ASN B CG  1 
ATOM   3008 O OD1 . ASN B 1 97  ? -17.79794 10.41375 -45.00406 1.000 29.00613 ? 98  ASN B OD1 1 
ATOM   3009 N ND2 . ASN B 1 97  ? -18.46912 12.51902 -45.49401 1.000 26.54717 ? 98  ASN B ND2 1 
ATOM   3010 N N   . PRO B 1 98  ? -18.27332 7.46356  -45.93380 1.000 28.88023 ? 99  PRO B N   1 
ATOM   3011 C CA  . PRO B 1 98  ? -18.89361 6.45598  -45.06218 1.000 31.38658 ? 99  PRO B CA  1 
ATOM   3012 C C   . PRO B 1 98  ? -19.54491 7.06550  -43.84444 1.000 30.39345 ? 99  PRO B C   1 
ATOM   3013 O O   . PRO B 1 98  ? -20.32411 6.38650  -43.16522 1.000 32.88494 ? 99  PRO B O   1 
ATOM   3014 C CB  . PRO B 1 98  ? -17.71609 5.55253  -44.67501 1.000 29.51400 ? 99  PRO B CB  1 
ATOM   3015 C CG  . PRO B 1 98  ? -16.53076 6.45662  -44.72400 1.000 31.71577 ? 99  PRO B CG  1 
ATOM   3016 C CD  . PRO B 1 98  ? -16.79953 7.43400  -45.84759 1.000 28.05309 ? 99  PRO B CD  1 
ATOM   3017 N N   . SER B 1 99  ? -19.25137 8.32747  -43.55390 1.000 31.93956 ? 100 SER B N   1 
ATOM   3018 C CA  . SER B 1 99  ? -19.83082 9.02214  -42.41908 1.000 28.54843 ? 100 SER B CA  1 
ATOM   3019 C C   . SER B 1 99  ? -20.66610 10.20327 -42.89803 1.000 31.60974 ? 100 SER B C   1 
ATOM   3020 O O   . SER B 1 99  ? -20.51778 11.31255 -42.38574 1.000 32.26997 ? 100 SER B O   1 
ATOM   3021 C CB  . SER B 1 99  ? -18.72305 9.48399  -41.47583 1.000 33.00468 ? 100 SER B CB  1 
ATOM   3022 O OG  . SER B 1 99  ? -18.02325 8.37031  -40.93514 1.000 32.98747 ? 100 SER B OG  1 
ATOM   3023 N N   . THR B 1 100 ? -21.52319 9.98137  -43.89335 1.000 29.19360 ? 101 THR B N   1 
ATOM   3024 C CA  . THR B 1 100 ? -22.45617 11.00362 -44.33623 1.000 29.89774 ? 101 THR B CA  1 
ATOM   3025 C C   . THR B 1 100 ? -23.61469 11.08735 -43.35197 1.000 31.25413 ? 101 THR B C   1 
ATOM   3026 O O   . THR B 1 100 ? -24.33742 10.09980 -43.17111 1.000 30.65220 ? 101 THR B O   1 
ATOM   3027 C CB  . THR B 1 100 ? -22.97867 10.69259 -45.73724 1.000 29.31312 ? 101 THR B CB  1 
ATOM   3028 O OG1 . THR B 1 100 ? -21.88147 10.58537 -46.65606 1.000 28.70590 ? 101 THR B OG1 1 
ATOM   3029 C CG2 . THR B 1 100 ? -23.91823 11.79137 -46.20754 1.000 29.03301 ? 101 THR B CG2 1 
ATOM   3030 N N   . PRO B 1 101 ? -23.82954 12.21833 -42.69382 1.000 28.69065 ? 102 PRO B N   1 
ATOM   3031 C CA  . PRO B 1 101 ? -24.99469 12.34385 -41.81954 1.000 31.76691 ? 102 PRO B CA  1 
ATOM   3032 C C   . PRO B 1 101 ? -26.27121 12.50848 -42.63185 1.000 32.77208 ? 102 PRO B C   1 
ATOM   3033 O O   . PRO B 1 101 ? -26.25392 12.82618 -43.82702 1.000 33.17649 ? 102 PRO B O   1 
ATOM   3034 C CB  . PRO B 1 101 ? -24.68390 13.60625 -41.00404 1.000 30.63646 ? 102 PRO B CB  1 
ATOM   3035 C CG  . PRO B 1 101 ? -23.88396 14.44125 -41.94479 1.000 29.68512 ? 102 PRO B CG  1 
ATOM   3036 C CD  . PRO B 1 101 ? -23.04314 13.46423 -42.75193 1.000 30.28463 ? 102 PRO B CD  1 
ATOM   3037 N N   . ALA B 1 102 ? -27.39577 12.24563 -41.96991 1.000 30.92119 ? 103 ALA B N   1 
ATOM   3038 C CA  . ALA B 1 102 ? -28.67607 12.66047 -42.52246 1.000 31.12316 ? 103 ALA B CA  1 
ATOM   3039 C C   . ALA B 1 102 ? -28.69220 14.18317 -42.65163 1.000 34.80947 ? 103 ALA B C   1 
ATOM   3040 O O   . ALA B 1 102 ? -28.38133 14.89749 -41.69291 1.000 33.44455 ? 103 ALA B O   1 
ATOM   3041 C CB  . ALA B 1 102 ? -29.81525 12.17645 -41.62791 1.000 31.99791 ? 103 ALA B CB  1 
ATOM   3042 N N   . TYR B 1 103 ? -29.04254 14.68934 -43.83414 1.000 29.86233 ? 104 TYR B N   1 
ATOM   3043 C CA  . TYR B 1 103 ? -28.88131 16.11932 -44.06477 1.000 32.20238 ? 104 TYR B CA  1 
ATOM   3044 C C   . TYR B 1 103 ? -29.93918 16.65978 -45.01990 1.000 31.62713 ? 104 TYR B C   1 
ATOM   3045 O O   . TYR B 1 103 ? -30.53103 15.92266 -45.81498 1.000 33.18782 ? 104 TYR B O   1 
ATOM   3046 C CB  . TYR B 1 103 ? -27.48017 16.42537 -44.60098 1.000 28.19697 ? 104 TYR B CB  1 
ATOM   3047 C CG  . TYR B 1 103 ? -27.25686 16.00084 -46.04077 1.000 29.88907 ? 104 TYR B CG  1 
ATOM   3048 C CD1 . TYR B 1 103 ? -27.52769 16.86908 -47.08932 1.000 27.84632 ? 104 TYR B CD1 1 
ATOM   3049 C CD2 . TYR B 1 103 ? -26.75139 14.73739 -46.35053 1.000 28.14294 ? 104 TYR B CD2 1 
ATOM   3050 C CE1 . TYR B 1 103 ? -27.32367 16.49230 -48.40142 1.000 30.57540 ? 104 TYR B CE1 1 
ATOM   3051 C CE2 . TYR B 1 103 ? -26.53936 14.35145 -47.67422 1.000 30.07864 ? 104 TYR B CE2 1 
ATOM   3052 C CZ  . TYR B 1 103 ? -26.82844 15.23196 -48.68742 1.000 32.70931 ? 104 TYR B CZ  1 
ATOM   3053 O OH  . TYR B 1 103 ? -26.61678 14.86875 -50.00306 1.000 35.43680 ? 104 TYR B OH  1 
ATOM   3054 N N   . THR B 1 104 ? -30.15416 17.97528 -44.93779 1.000 31.27809 ? 105 THR B N   1 
ATOM   3055 C CA  . THR B 1 104 ? -30.96006 18.73767 -45.88904 1.000 32.40998 ? 105 THR B CA  1 
ATOM   3056 C C   . THR B 1 104 ? -30.19341 19.98710 -46.30829 1.000 33.10892 ? 105 THR B C   1 
ATOM   3057 O O   . THR B 1 104 ? -29.15666 20.32921 -45.73113 1.000 31.97482 ? 105 THR B O   1 
ATOM   3058 C CB  . THR B 1 104 ? -32.32538 19.15432 -45.30397 1.000 34.69427 ? 105 THR B CB  1 
ATOM   3059 O OG1 . THR B 1 104 ? -32.12840 20.08743 -44.23030 1.000 36.29374 ? 105 THR B OG1 1 
ATOM   3060 C CG2 . THR B 1 104 ? -33.10929 17.95141 -44.79125 1.000 35.58515 ? 105 THR B CG2 1 
ATOM   3061 N N   . PHE B 1 105 ? -30.73055 20.68134 -47.31534 1.000 32.29995 ? 106 PHE B N   1 
ATOM   3062 C CA  . PHE B 1 105 ? -30.19342 21.94577 -47.81996 1.000 29.85297 ? 106 PHE B CA  1 
ATOM   3063 C C   . PHE B 1 105 ? -31.30534 22.98988 -47.73536 1.000 38.34407 ? 106 PHE B C   1 
ATOM   3064 O O   . PHE B 1 105 ? -32.13737 23.07720 -48.64313 1.000 43.56561 ? 106 PHE B O   1 
ATOM   3065 C CB  . PHE B 1 105 ? -29.72607 21.82994 -49.26651 1.000 29.91494 ? 106 PHE B CB  1 
ATOM   3066 C CG  . PHE B 1 105 ? -28.51708 20.96420 -49.47484 1.000 31.11670 ? 106 PHE B CG  1 
ATOM   3067 C CD1 . PHE B 1 105 ? -27.49939 20.90781 -48.53449 1.000 27.04549 ? 106 PHE B CD1 1 
ATOM   3068 C CD2 . PHE B 1 105 ? -28.38494 20.23001 -50.64719 1.000 32.93864 ? 106 PHE B CD2 1 
ATOM   3069 C CE1 . PHE B 1 105 ? -26.39199 20.13562 -48.75256 1.000 28.69461 ? 106 PHE B CE1 1 
ATOM   3070 C CE2 . PHE B 1 105 ? -27.29303 19.43535 -50.86222 1.000 30.62696 ? 106 PHE B CE2 1 
ATOM   3071 C CZ  . PHE B 1 105 ? -26.28859 19.38588 -49.92384 1.000 30.58939 ? 106 PHE B CZ  1 
ATOM   3072 N N   . THR B 1 106 ? -31.32316 23.81018 -46.69084 1.000 32.78668 ? 107 THR B N   1 
ATOM   3073 C CA  . THR B 1 106 ? -32.30732 24.88532 -46.59715 1.000 36.43883 ? 107 THR B CA  1 
ATOM   3074 C C   . THR B 1 106 ? -31.60339 26.23107 -46.48339 1.000 36.04737 ? 107 THR B C   1 
ATOM   3075 O O   . THR B 1 106 ? -30.57753 26.35127 -45.81020 1.000 38.80872 ? 107 THR B O   1 
ATOM   3076 C CB  . THR B 1 106 ? -33.25868 24.69059 -45.40780 1.000 42.50622 ? 107 THR B CB  1 
ATOM   3077 O OG1 . THR B 1 106 ? -33.79630 23.35969 -45.43575 1.000 47.07498 ? 107 THR B OG1 1 
ATOM   3078 C CG2 . THR B 1 106 ? -34.41805 25.68513 -45.48211 1.000 40.20369 ? 107 THR B CG2 1 
ATOM   3079 N N   . THR B 1 107 ? -32.14030 27.23430 -47.16983 1.000 29.84998 ? 108 THR B N   1 
ATOM   3080 C CA  . THR B 1 107 ? -31.58653 28.57858 -47.11498 1.000 33.92806 ? 108 THR B CA  1 
ATOM   3081 C C   . THR B 1 107 ? -32.05842 29.27044 -45.83583 1.000 33.53337 ? 108 THR B C   1 
ATOM   3082 O O   . THR B 1 107 ? -33.24980 29.24427 -45.52237 1.000 29.81193 ? 108 THR B O   1 
ATOM   3083 C CB  . THR B 1 107 ? -32.02668 29.36779 -48.35357 1.000 33.87111 ? 108 THR B CB  1 
ATOM   3084 O OG1 . THR B 1 107 ? -31.67148 28.64028 -49.54007 1.000 35.22337 ? 108 THR B OG1 1 
ATOM   3085 C CG2 . THR B 1 107 ? -31.39318 30.75007 -48.38811 1.000 31.08732 ? 108 THR B CG2 1 
ATOM   3086 N N   . VAL B 1 108 ? -31.12764 29.88202 -45.08285 1.000 30.21405 ? 109 VAL B N   1 
ATOM   3087 C CA  . VAL B 1 108 ? -31.52289 30.56375 -43.84995 1.000 33.13352 ? 109 VAL B CA  1 
ATOM   3088 C C   . VAL B 1 108 ? -31.97000 31.97912 -44.17634 1.000 31.94231 ? 109 VAL B C   1 
ATOM   3089 O O   . VAL B 1 108 ? -31.56308 32.57109 -45.18013 1.000 29.86707 ? 109 VAL B O   1 
ATOM   3090 C CB  . VAL B 1 108 ? -30.39330 30.57720 -42.79779 1.000 30.01166 ? 109 VAL B CB  1 
ATOM   3091 C CG1 . VAL B 1 108 ? -30.15700 29.19519 -42.26200 1.000 33.58822 ? 109 VAL B CG1 1 
ATOM   3092 C CG2 . VAL B 1 108 ? -29.12693 31.18831 -43.36800 1.000 29.33713 ? 109 VAL B CG2 1 
ATOM   3093 N N   . LYS B 1 109 ? -32.79990 32.52475 -43.31115 1.000 35.57349 ? 110 LYS B N   1 
ATOM   3094 C CA  . LYS B 1 109 ? -33.34222 33.86679 -43.41264 1.000 33.27518 ? 110 LYS B CA  1 
ATOM   3095 C C   . LYS B 1 109 ? -32.61109 34.80794 -42.46583 1.000 31.65863 ? 110 LYS B C   1 
ATOM   3096 O O   . LYS B 1 109 ? -32.02270 34.37274 -41.47046 1.000 30.16807 ? 110 LYS B O   1 
ATOM   3097 C CB  . LYS B 1 109 ? -34.83981 33.85016 -43.08214 1.000 33.80071 ? 110 LYS B CB  1 
ATOM   3098 C CG  . LYS B 1 109 ? -35.61295 32.77190 -43.85975 1.000 40.39691 ? 110 LYS B CG  1 
ATOM   3099 C CD  . LYS B 1 109 ? -37.09646 33.09227 -43.93873 1.000 42.63967 ? 110 LYS B CD  1 
ATOM   3100 C CE  . LYS B 1 109 ? -37.87524 32.03310 -44.71973 1.000 44.78263 ? 110 LYS B CE  1 
ATOM   3101 N NZ  . LYS B 1 109 ? -38.60718 31.09629 -43.81425 1.000 51.80209 ? 110 LYS B NZ  1 
ATOM   3102 N N   . PRO B 1 110 ? -32.61945 36.10915 -42.75122 1.000 31.58495 ? 111 PRO B N   1 
ATOM   3103 C CA  . PRO B 1 110 ? -31.94017 37.05453 -41.85952 1.000 28.94943 ? 111 PRO B CA  1 
ATOM   3104 C C   . PRO B 1 110 ? -32.49042 36.95501 -40.45048 1.000 27.84819 ? 111 PRO B C   1 
ATOM   3105 O O   . PRO B 1 110 ? -33.68977 36.76352 -40.24686 1.000 28.09668 ? 111 PRO B O   1 
ATOM   3106 C CB  . PRO B 1 110 ? -32.24451 38.41561 -42.49057 1.000 27.86022 ? 111 PRO B CB  1 
ATOM   3107 C CG  . PRO B 1 110 ? -32.40887 38.10015 -43.93915 1.000 33.08359 ? 111 PRO B CG  1 
ATOM   3108 C CD  . PRO B 1 110 ? -33.10551 36.77090 -43.97812 1.000 31.90412 ? 111 PRO B CD  1 
ATOM   3109 N N   . GLY B 1 111 ? -31.59763 37.09154 -39.47059 1.000 26.01428 ? 112 GLY B N   1 
ATOM   3110 C CA  . GLY B 1 111 ? -31.96456 36.92799 -38.08551 1.000 25.26130 ? 112 GLY B CA  1 
ATOM   3111 C C   . GLY B 1 111 ? -31.82073 35.51730 -37.55967 1.000 24.61398 ? 112 GLY B C   1 
ATOM   3112 O O   . GLY B 1 111 ? -31.69487 35.33615 -36.34263 1.000 27.22011 ? 112 GLY B O   1 
ATOM   3113 N N   . ALA B 1 112 ? -31.81147 34.51224 -38.43456 1.000 24.31671 ? 113 ALA B N   1 
ATOM   3114 C CA  . ALA B 1 112 ? -31.64099 33.13794 -37.98259 1.000 27.37295 ? 113 ALA B CA  1 
ATOM   3115 C C   . ALA B 1 112 ? -30.17246 32.84200 -37.68502 1.000 24.61327 ? 113 ALA B C   1 
ATOM   3116 O O   . ALA B 1 112 ? -29.26279 33.35438 -38.34298 1.000 25.68497 ? 113 ALA B O   1 
ATOM   3117 C CB  . ALA B 1 112 ? -32.16669 32.14489 -39.02376 1.000 25.81044 ? 113 ALA B CB  1 
ATOM   3118 N N   . ALA B 1 113 ? -29.95778 31.99963 -36.68080 1.000 24.87000 ? 114 ALA B N   1 
ATOM   3119 C CA  . ALA B 1 113 ? -28.63722 31.62876 -36.19872 1.000 21.65900 ? 114 ALA B CA  1 
ATOM   3120 C C   . ALA B 1 113 ? -28.18863 30.32698 -36.84167 1.000 23.53494 ? 114 ALA B C   1 
ATOM   3121 O O   . ALA B 1 113 ? -28.99832 29.43939 -37.12045 1.000 26.06930 ? 114 ALA B O   1 
ATOM   3122 C CB  . ALA B 1 113 ? -28.65239 31.44730 -34.67922 1.000 23.50608 ? 114 ALA B CB  1 
ATOM   3123 N N   . PHE B 1 114 ? -26.88678 30.20055 -37.06159 1.000 19.97671 ? 115 PHE B N   1 
ATOM   3124 C CA  . PHE B 1 114 ? -26.38004 28.88697 -37.41693 1.000 21.46202 ? 115 PHE B CA  1 
ATOM   3125 C C   . PHE B 1 114 ? -24.94401 28.75988 -36.93897 1.000 22.02733 ? 115 PHE B C   1 
ATOM   3126 O O   . PHE B 1 114 ? -24.28549 29.75177 -36.62313 1.000 20.40132 ? 115 PHE B O   1 
ATOM   3127 C CB  . PHE B 1 114 ? -26.48469 28.61050 -38.92346 1.000 20.25690 ? 115 PHE B CB  1 
ATOM   3128 C CG  . PHE B 1 114 ? -25.79857 29.60924 -39.79311 1.000 20.48021 ? 115 PHE B CG  1 
ATOM   3129 C CD1 . PHE B 1 114 ? -26.45726 30.76660 -40.19562 1.000 21.64629 ? 115 PHE B CD1 1 
ATOM   3130 C CD2 . PHE B 1 114 ? -24.50462 29.37700 -40.26100 1.000 19.50955 ? 115 PHE B CD2 1 
ATOM   3131 C CE1 . PHE B 1 114 ? -25.84850 31.68804 -41.03115 1.000 22.62107 ? 115 PHE B CE1 1 
ATOM   3132 C CE2 . PHE B 1 114 ? -23.87528 30.29852 -41.09584 1.000 23.03772 ? 115 PHE B CE2 1 
ATOM   3133 C CZ  . PHE B 1 114 ? -24.54956 31.46514 -41.48852 1.000 22.70634 ? 115 PHE B CZ  1 
ATOM   3134 N N   . SER B 1 115 ? -24.47951 27.51430 -36.88480 1.000 18.59745 ? 116 SER B N   1 
ATOM   3135 C CA  . SER B 1 115 ? -23.11890 27.18786 -36.48122 1.000 19.75497 ? 116 SER B CA  1 
ATOM   3136 C C   . SER B 1 115 ? -22.20714 27.12568 -37.69164 1.000 18.99602 ? 116 SER B C   1 
ATOM   3137 O O   . SER B 1 115 ? -22.60401 26.64128 -38.75237 1.000 20.96364 ? 116 SER B O   1 
ATOM   3138 C CB  . SER B 1 115 ? -23.08533 25.84462 -35.74974 1.000 20.00131 ? 116 SER B CB  1 
ATOM   3139 O OG  . SER B 1 115 ? -23.70703 25.96033 -34.49341 1.000 22.33076 ? 116 SER B OG  1 
ATOM   3140 N N   . VAL B 1 116 ? -20.96964 27.57611 -37.51666 1.000 17.76492 ? 117 VAL B N   1 
ATOM   3141 C CA  . VAL B 1 116 ? -19.97126 27.57196 -38.57799 1.000 18.85107 ? 117 VAL B CA  1 
ATOM   3142 C C   . VAL B 1 116 ? -18.77223 26.75372 -38.12308 1.000 20.85700 ? 117 VAL B C   1 
ATOM   3143 O O   . VAL B 1 116 ? -18.27410 26.94113 -37.00391 1.000 19.47108 ? 117 VAL B O   1 
ATOM   3144 C CB  . VAL B 1 116 ? -19.54550 29.00207 -38.94722 1.000 19.71075 ? 117 VAL B CB  1 
ATOM   3145 C CG1 . VAL B 1 116 ? -18.38310 28.96886 -39.93210 1.000 21.86747 ? 117 VAL B CG1 1 
ATOM   3146 C CG2 . VAL B 1 116 ? -20.73022 29.73229 -39.55745 1.000 20.45336 ? 117 VAL B CG2 1 
ATOM   3147 N N   . LEU B 1 117 ? -18.30532 25.85664 -38.99232 1.000 20.50849 ? 118 LEU B N   1 
ATOM   3148 C CA  . LEU B 1 117 ? -17.03976 25.15733 -38.79797 1.000 20.84351 ? 118 LEU B CA  1 
ATOM   3149 C C   . LEU B 1 117 ? -15.99959 25.79581 -39.72292 1.000 23.56513 ? 118 LEU B C   1 
ATOM   3150 O O   . LEU B 1 117 ? -16.01738 25.57670 -40.94538 1.000 21.19038 ? 118 LEU B O   1 
ATOM   3151 C CB  . LEU B 1 117 ? -17.19364 23.66338 -39.07860 1.000 15.91540 ? 118 LEU B CB  1 
ATOM   3152 C CG  . LEU B 1 117 ? -15.92776 22.83983 -38.85517 1.000 21.14864 ? 118 LEU B CG  1 
ATOM   3153 C CD1 . LEU B 1 117 ? -15.57629 22.90987 -37.38112 1.000 18.77832 ? 118 LEU B CD1 1 
ATOM   3154 C CD2 . LEU B 1 117 ? -16.16092 21.38526 -39.28759 1.000 19.81159 ? 118 LEU B CD2 1 
ATOM   3155 N N   . ALA B 1 118 ? -15.08307 26.56746 -39.14051 1.000 18.70572 ? 119 ALA B N   1 
ATOM   3156 C CA  . ALA B 1 118 ? -14.01705 27.20037 -39.90876 1.000 19.39703 ? 119 ALA B CA  1 
ATOM   3157 C C   . ALA B 1 118 ? -12.88173 26.21083 -40.16453 1.000 22.04824 ? 119 ALA B C   1 
ATOM   3158 O O   . ALA B 1 118 ? -12.37549 25.57458 -39.23481 1.000 21.90037 ? 119 ALA B O   1 
ATOM   3159 C CB  . ALA B 1 118 ? -13.48097 28.42535 -39.17403 1.000 20.99793 ? 119 ALA B CB  1 
ATOM   3160 N N   . CYS B 1 119 ? -12.48337 26.08279 -41.41996 1.000 19.84823 ? 120 CYS B N   1 
ATOM   3161 C CA  . CYS B 1 119 ? -11.43854 25.14010 -41.80337 1.000 23.59305 ? 120 CYS B CA  1 
ATOM   3162 C C   . CYS B 1 119 ? -10.43311 25.82362 -42.70914 1.000 23.81617 ? 120 CYS B C   1 
ATOM   3163 O O   . CYS B 1 119 ? -10.72212 26.83808 -43.35358 1.000 24.21630 ? 120 CYS B O   1 
ATOM   3164 C CB  . CYS B 1 119 ? -11.98662 23.90314 -42.53379 1.000 22.85517 ? 120 CYS B CB  1 
ATOM   3165 S SG  . CYS B 1 119 ? -13.40207 23.14857 -41.73371 1.000 27.39091 ? 120 CYS B SG  1 
ATOM   3166 N N   . TYR B 1 120 ? -9.23682  25.24345 -42.73786 1.000 21.84413 ? 121 TYR B N   1 
ATOM   3167 C CA  . TYR B 1 120 ? -8.15169  25.70901 -43.58403 1.000 25.24176 ? 121 TYR B CA  1 
ATOM   3168 C C   . TYR B 1 120 ? -7.47355  24.48023 -44.15852 1.000 24.86921 ? 121 TYR B C   1 
ATOM   3169 O O   . TYR B 1 120 ? -7.11763  23.56210 -43.41181 1.000 23.38530 ? 121 TYR B O   1 
ATOM   3170 C CB  . TYR B 1 120 ? -7.17945  26.59573 -42.78471 1.000 23.35083 ? 121 TYR B CB  1 
ATOM   3171 C CG  . TYR B 1 120 ? -7.91617  27.81011 -42.23784 1.000 26.20173 ? 121 TYR B CG  1 
ATOM   3172 C CD1 . TYR B 1 120 ? -8.55850  27.76345 -41.00315 1.000 25.46848 ? 121 TYR B CD1 1 
ATOM   3173 C CD2 . TYR B 1 120 ? -8.02638  28.97073 -42.99182 1.000 24.56624 ? 121 TYR B CD2 1 
ATOM   3174 C CE1 . TYR B 1 120 ? -9.28345  28.86278 -40.52593 1.000 26.93947 ? 121 TYR B CE1 1 
ATOM   3175 C CE2 . TYR B 1 120 ? -8.73739  30.07209 -42.52593 1.000 27.16151 ? 121 TYR B CE2 1 
ATOM   3176 C CZ  . TYR B 1 120 ? -9.36722  30.01684 -41.29377 1.000 27.78675 ? 121 TYR B CZ  1 
ATOM   3177 O OH  . TYR B 1 120 ? -10.08155 31.10955 -40.82671 1.000 25.84273 ? 121 TYR B OH  1 
ATOM   3178 N N   . ASN B 1 121 ? -7.36737  24.43238 -45.48386 1.000 26.57939 ? 122 ASN B N   1 
ATOM   3179 C CA  . ASN B 1 121 ? -6.70854  23.31725 -46.16011 1.000 26.76275 ? 122 ASN B CA  1 
ATOM   3180 C C   . ASN B 1 121 ? -7.37818  21.99376 -45.80977 1.000 27.13721 ? 122 ASN B C   1 
ATOM   3181 O O   . ASN B 1 121 ? -6.71858  20.96433 -45.65480 1.000 27.45256 ? 122 ASN B O   1 
ATOM   3182 C CB  . ASN B 1 121 ? -5.21480  23.29020 -45.82369 1.000 29.90278 ? 122 ASN B CB  1 
ATOM   3183 C CG  . ASN B 1 121 ? -4.52766  24.59065 -46.19152 1.000 32.73632 ? 122 ASN B CG  1 
ATOM   3184 O OD1 . ASN B 1 121 ? -4.54058  24.98609 -47.35477 1.000 32.06910 ? 122 ASN B OD1 1 
ATOM   3185 N ND2 . ASN B 1 121 ? -3.94279  25.27274 -45.20305 1.000 35.90524 ? 122 ASN B ND2 1 
ATOM   3186 N N   . GLY B 1 122 ? -8.70539  22.02440 -45.68294 1.000 24.61738 ? 123 GLY B N   1 
ATOM   3187 C CA  . GLY B 1 122 ? -9.44970  20.83953 -45.31818 1.000 24.88147 ? 123 GLY B CA  1 
ATOM   3188 C C   . GLY B 1 122 ? -9.33722  20.41775 -43.86877 1.000 28.42703 ? 123 GLY B C   1 
ATOM   3189 O O   . GLY B 1 122 ? -9.73791  19.29679 -43.53559 1.000 27.25367 ? 123 GLY B O   1 
ATOM   3190 N N   . ARG B 1 123 ? -8.80689  21.26561 -42.98901 1.000 22.92154 ? 124 ARG B N   1 
ATOM   3191 C CA  . ARG B 1 123 ? -8.63304  20.89573 -41.58019 1.000 24.80087 ? 124 ARG B CA  1 
ATOM   3192 C C   . ARG B 1 123 ? -9.45566  21.83151 -40.71198 1.000 23.85051 ? 124 ARG B C   1 
ATOM   3193 O O   . ARG B 1 123 ? -9.21327  23.04680 -40.73198 1.000 24.10140 ? 124 ARG B O   1 
ATOM   3194 C CB  . ARG B 1 123 ? -7.16065  20.96259 -41.15249 1.000 28.82749 ? 124 ARG B CB  1 
ATOM   3195 C CG  . ARG B 1 123 ? -6.26030  20.00066 -41.89360 1.000 35.37321 ? 124 ARG B CG  1 
ATOM   3196 C CD  . ARG B 1 123 ? -4.94904  19.82127 -41.15274 1.000 41.40590 ? 124 ARG B CD  1 
ATOM   3197 N NE  . ARG B 1 123 ? -4.43634  18.47380 -41.34892 1.000 48.55679 ? 124 ARG B NE  1 
ATOM   3198 C CZ  . ARG B 1 123 ? -3.77024  18.09731 -42.43237 1.000 51.45387 ? 124 ARG B CZ  1 
ATOM   3199 N NH1 . ARG B 1 123 ? -3.53093  18.98403 -43.39717 1.000 52.17248 ? 124 ARG B NH1 1 
ATOM   3200 N NH2 . ARG B 1 123 ? -3.34253  16.84456 -42.55068 1.000 45.93198 ? 124 ARG B NH2 1 
ATOM   3201 N N   . PRO B 1 124 ? -10.41816 21.33095 -39.94346 1.000 27.73009 ? 125 PRO B N   1 
ATOM   3202 C CA  . PRO B 1 124 ? -11.17042 22.20929 -39.03584 1.000 25.88003 ? 125 PRO B CA  1 
ATOM   3203 C C   . PRO B 1 124 ? -10.27194 22.82766 -37.97667 1.000 22.76745 ? 125 PRO B C   1 
ATOM   3204 O O   . PRO B 1 124 ? -9.45068  22.14590 -37.35982 1.000 19.97405 ? 125 PRO B O   1 
ATOM   3205 C CB  . PRO B 1 124 ? -12.20049 21.26810 -38.40322 1.000 22.54974 ? 125 PRO B CB  1 
ATOM   3206 C CG  . PRO B 1 124 ? -12.35616 20.14859 -39.40718 1.000 23.70141 ? 125 PRO B CG  1 
ATOM   3207 C CD  . PRO B 1 124 ? -10.96544 19.96422 -39.98364 1.000 25.25999 ? 125 PRO B CD  1 
ATOM   3208 N N   . THR B 1 125 ? -10.46163 24.12517 -37.74181 1.000 21.05314 ? 126 THR B N   1 
ATOM   3209 C CA  . THR B 1 125 ? -9.68926  24.83303 -36.73094 1.000 20.34566 ? 126 THR B CA  1 
ATOM   3210 C C   . THR B 1 125 ? -10.53403 25.49656 -35.65090 1.000 23.86650 ? 126 THR B C   1 
ATOM   3211 O O   . THR B 1 125 ? -9.98511  25.85178 -34.60574 1.000 21.49600 ? 126 THR B O   1 
ATOM   3212 C CB  . THR B 1 125 ? -8.79271  25.89995 -37.37705 1.000 19.70444 ? 126 THR B CB  1 
ATOM   3213 O OG1 . THR B 1 125 ? -9.60497  26.83504 -38.08140 1.000 26.29968 ? 126 THR B OG1 1 
ATOM   3214 C CG2 . THR B 1 125 ? -7.79038  25.25918 -38.36476 1.000 25.67230 ? 126 THR B CG2 1 
ATOM   3215 N N   . GLY B 1 126 ? -11.82941 25.69595 -35.86684 1.000 20.92580 ? 127 GLY B N   1 
ATOM   3216 C CA  . GLY B 1 126 ? -12.63649 26.35802 -34.86553 1.000 20.48968 ? 127 GLY B CA  1 
ATOM   3217 C C   . GLY B 1 126 ? -14.10180 26.36102 -35.25639 1.000 21.93213 ? 127 GLY B C   1 
ATOM   3218 O O   . GLY B 1 126 ? -14.46542 26.13630 -36.41452 1.000 21.44852 ? 127 GLY B O   1 
ATOM   3219 N N   . THR B 1 127 ? -14.94315 26.62862 -34.26280 1.000 20.49509 ? 128 THR B N   1 
ATOM   3220 C CA  . THR B 1 127 ? -16.37469 26.69370 -34.50592 1.000 22.27857 ? 128 THR B CA  1 
ATOM   3221 C C   . THR B 1 127 ? -16.94371 27.88234 -33.74299 1.000 23.12062 ? 128 THR B C   1 
ATOM   3222 O O   . THR B 1 127 ? -16.45457 28.25766 -32.66958 1.000 18.88607 ? 128 THR B O   1 
ATOM   3223 C CB  . THR B 1 127 ? -17.09537 25.36652 -34.13690 1.000 25.62247 ? 128 THR B CB  1 
ATOM   3224 O OG1 . THR B 1 127 ? -18.45473 25.40478 -34.60106 1.000 27.40761 ? 128 THR B OG1 1 
ATOM   3225 C CG2 . THR B 1 127 ? -17.09010 25.12415 -32.62701 1.000 25.32831 ? 128 THR B CG2 1 
ATOM   3226 N N   . PHE B 1 128 ? -17.95855 28.50033 -34.33769 1.000 20.12530 ? 129 PHE B N   1 
ATOM   3227 C CA  . PHE B 1 128 ? -18.60343 29.65416 -33.73287 1.000 21.47815 ? 129 PHE B CA  1 
ATOM   3228 C C   . PHE B 1 128 ? -20.00968 29.73008 -34.30359 1.000 22.42526 ? 129 PHE B C   1 
ATOM   3229 O O   . PHE B 1 128 ? -20.35541 29.00653 -35.23928 1.000 20.56733 ? 129 PHE B O   1 
ATOM   3230 C CB  . PHE B 1 128 ? -17.81174 30.94313 -33.98865 1.000 18.64897 ? 129 PHE B CB  1 
ATOM   3231 C CG  . PHE B 1 128 ? -17.54739 31.23548 -35.45525 1.000 21.79213 ? 129 PHE B CG  1 
ATOM   3232 C CD1 . PHE B 1 128 ? -18.44985 31.96243 -36.20445 1.000 20.24297 ? 129 PHE B CD1 1 
ATOM   3233 C CD2 . PHE B 1 128 ? -16.38325 30.80771 -36.06954 1.000 24.98550 ? 129 PHE B CD2 1 
ATOM   3234 C CE1 . PHE B 1 128 ? -18.20545 32.24293 -37.54844 1.000 24.34233 ? 129 PHE B CE1 1 
ATOM   3235 C CE2 . PHE B 1 128 ? -16.13857 31.08789 -37.41060 1.000 21.54417 ? 129 PHE B CE2 1 
ATOM   3236 C CZ  . PHE B 1 128 ? -17.05715 31.81646 -38.14493 1.000 21.65615 ? 129 PHE B CZ  1 
ATOM   3237 N N   . THR B 1 129 ? -20.81253 30.62011 -33.74292 1.000 19.28585 ? 130 THR B N   1 
ATOM   3238 C CA  . THR B 1 129 ? -22.17392 30.80952 -34.21546 1.000 23.26809 ? 130 THR B CA  1 
ATOM   3239 C C   . THR B 1 129 ? -22.38605 32.26279 -34.63433 1.000 27.06150 ? 130 THR B C   1 
ATOM   3240 O O   . THR B 1 129 ? -21.82867 33.18595 -34.02275 1.000 22.58284 ? 130 THR B O   1 
ATOM   3241 C CB  . THR B 1 129 ? -23.17353 30.39354 -33.14585 1.000 25.64886 ? 130 THR B CB  1 
ATOM   3242 O OG1 . THR B 1 129 ? -24.50032 30.48597 -33.67263 1.000 25.87626 ? 130 THR B OG1 1 
ATOM   3243 C CG2 . THR B 1 129 ? -23.05429 31.26634 -31.92582 1.000 28.87901 ? 130 THR B CG2 1 
ATOM   3244 N N   . VAL B 1 130 ? -23.18138 32.45725 -35.69203 1.000 21.07833 ? 131 VAL B N   1 
ATOM   3245 C CA  . VAL B 1 130 ? -23.49380 33.78208 -36.22271 1.000 24.55438 ? 131 VAL B CA  1 
ATOM   3246 C C   . VAL B 1 130 ? -24.98915 33.83387 -36.49666 1.000 23.71852 ? 131 VAL B C   1 
ATOM   3247 O O   . VAL B 1 130 ? -25.66291 32.80817 -36.55110 1.000 24.36447 ? 131 VAL B O   1 
ATOM   3248 C CB  . VAL B 1 130 ? -22.70964 34.11045 -37.51602 1.000 24.91292 ? 131 VAL B CB  1 
ATOM   3249 C CG1 . VAL B 1 130 ? -21.22166 34.14109 -37.26346 1.000 25.33757 ? 131 VAL B CG1 1 
ATOM   3250 C CG2 . VAL B 1 130 ? -23.03776 33.10972 -38.61949 1.000 25.40370 ? 131 VAL B CG2 1 
ATOM   3251 N N   . VAL B 1 131 ? -25.50638 35.03978 -36.70807 1.000 25.84886 ? 132 VAL B N   1 
ATOM   3252 C CA  . VAL B 1 131 ? -26.83803 35.19767 -37.28990 1.000 23.73712 ? 132 VAL B CA  1 
ATOM   3253 C C   . VAL B 1 131 ? -26.67344 35.79973 -38.67602 1.000 21.81622 ? 132 VAL B C   1 
ATOM   3254 O O   . VAL B 1 131 ? -25.77688 36.61974 -38.90851 1.000 24.90306 ? 132 VAL B O   1 
ATOM   3255 C CB  . VAL B 1 131 ? -27.77996 36.05845 -36.42349 1.000 28.21165 ? 132 VAL B CB  1 
ATOM   3256 C CG1 . VAL B 1 131 ? -28.22516 35.28174 -35.17760 1.000 25.89448 ? 132 VAL B CG1 1 
ATOM   3257 C CG2 . VAL B 1 131 ? -27.10684 37.33369 -36.04038 1.000 28.38957 ? 132 VAL B CG2 1 
ATOM   3258 N N   . MET B 1 132 ? -27.52055 35.37148 -39.61046 1.000 22.29790 ? 133 MET B N   1 
ATOM   3259 C CA  . MET B 1 132 ? -27.51215 35.98209 -40.93630 1.000 23.90088 ? 133 MET B CA  1 
ATOM   3260 C C   . MET B 1 132 ? -27.97863 37.42806 -40.79861 1.000 23.98931 ? 133 MET B C   1 
ATOM   3261 O O   . MET B 1 132 ? -29.07854 37.67334 -40.30101 1.000 25.14810 ? 133 MET B O   1 
ATOM   3262 C CB  . MET B 1 132 ? -28.42067 35.20612 -41.88971 1.000 23.54615 ? 133 MET B CB  1 
ATOM   3263 C CG  . MET B 1 132 ? -28.49500 35.79037 -43.30696 1.000 24.15868 ? 133 MET B CG  1 
ATOM   3264 S SD  . MET B 1 132 ? -26.92589 35.86810 -44.16979 1.000 28.77482 ? 133 MET B SD  1 
ATOM   3265 C CE  . MET B 1 132 ? -26.50366 34.11549 -44.22200 1.000 27.00340 ? 133 MET B CE  1 
ATOM   3266 N N   . ARG B 1 133 ? -27.14832 38.38561 -41.21333 1.000 26.45599 ? 134 ARG B N   1 
ATOM   3267 C CA  . ARG B 1 133 ? -27.54523 39.78001 -41.06912 1.000 25.72333 ? 134 ARG B CA  1 
ATOM   3268 C C   . ARG B 1 133 ? -28.62358 40.14939 -42.09478 1.000 27.73672 ? 134 ARG B C   1 
ATOM   3269 O O   . ARG B 1 133 ? -28.76885 39.49349 -43.13396 1.000 26.37976 ? 134 ARG B O   1 
ATOM   3270 C CB  . ARG B 1 133 ? -26.34566 40.71595 -41.21640 1.000 28.85469 ? 134 ARG B CB  1 
ATOM   3271 C CG  . ARG B 1 133 ? -25.24169 40.55319 -40.16581 1.000 28.99322 ? 134 ARG B CG  1 
ATOM   3272 C CD  . ARG B 1 133 ? -25.77134 40.62086 -38.74499 1.000 25.63177 ? 134 ARG B CD  1 
ATOM   3273 N NE  . ARG B 1 133 ? -26.61604 41.79463 -38.48830 1.000 28.47068 ? 134 ARG B NE  1 
ATOM   3274 C CZ  . ARG B 1 133 ? -27.22400 42.02295 -37.32437 1.000 28.90963 ? 134 ARG B CZ  1 
ATOM   3275 N NH1 . ARG B 1 133 ? -27.06219 41.18087 -36.30462 1.000 28.70510 ? 134 ARG B NH1 1 
ATOM   3276 N NH2 . ARG B 1 133 ? -27.98486 43.09787 -37.16970 1.000 29.79714 ? 134 ARG B NH2 1 
ATOM   3277 N N   . PRO B 1 134 ? -29.40455 41.19652 -41.80700 1.000 27.70494 ? 135 PRO B N   1 
ATOM   3278 C CA  . PRO B 1 134 ? -30.40849 41.66026 -42.78203 1.000 25.74509 ? 135 PRO B CA  1 
ATOM   3279 C C   . PRO B 1 134 ? -29.82404 42.10302 -44.11468 1.000 28.48079 ? 135 PRO B C   1 
ATOM   3280 O O   . PRO B 1 134 ? -30.54450 42.07769 -45.11646 1.000 28.54863 ? 135 PRO B O   1 
ATOM   3281 C CB  . PRO B 1 134 ? -31.09384 42.82556 -42.04686 1.000 28.49053 ? 135 PRO B CB  1 
ATOM   3282 C CG  . PRO B 1 134 ? -30.90564 42.49782 -40.58165 1.000 30.97417 ? 135 PRO B CG  1 
ATOM   3283 C CD  . PRO B 1 134 ? -29.55660 41.84714 -40.49003 1.000 26.75013 ? 135 PRO B CD  1 
ATOM   3284 N N   . ASN B 1 135 ? -28.55569 42.51486 -44.17629 1.000 27.29956 ? 136 ASN B N   1 
ATOM   3285 C CA  . ASN B 1 135 ? -27.92309 42.78908 -45.46006 1.000 28.27763 ? 136 ASN B CA  1 
ATOM   3286 C C   . ASN B 1 135 ? -27.20564 41.56817 -46.03906 1.000 26.50882 ? 136 ASN B C   1 
ATOM   3287 O O   . ASN B 1 135 ? -26.32140 41.72876 -46.88988 1.000 29.55284 ? 136 ASN B O   1 
ATOM   3288 C CB  . ASN B 1 135 ? -26.95673 43.96266 -45.33925 1.000 28.07393 ? 136 ASN B CB  1 
ATOM   3289 C CG  . ASN B 1 135 ? -25.75269 43.64890 -44.46163 1.000 31.76348 ? 136 ASN B CG  1 
ATOM   3290 O OD1 . ASN B 1 135 ? -25.62998 42.55408 -43.90178 1.000 28.23224 ? 136 ASN B OD1 1 
ATOM   3291 N ND2 . ASN B 1 135 ? -24.84672 44.60843 -44.35789 1.000 30.93919 ? 136 ASN B ND2 1 
ATOM   3292 N N   . TYR B 1 136 ? -27.55688 40.36948 -45.57668 1.000 24.60216 ? 137 TYR B N   1 
ATOM   3293 C CA  . TYR B 1 136 ? -27.09204 39.09675 -46.15314 1.000 29.54206 ? 137 TYR B CA  1 
ATOM   3294 C C   . TYR B 1 136 ? -25.57741 38.95494 -46.10056 1.000 27.94237 ? 137 TYR B C   1 
ATOM   3295 O O   . TYR B 1 136 ? -24.95325 38.41922 -47.01725 1.000 29.51395 ? 137 TYR B O   1 
ATOM   3296 C CB  . TYR B 1 136 ? -27.60726 38.92364 -47.57947 1.000 25.91870 ? 137 TYR B CB  1 
ATOM   3297 C CG  . TYR B 1 136 ? -29.10611 38.79856 -47.60289 1.000 27.58874 ? 137 TYR B CG  1 
ATOM   3298 C CD1 . TYR B 1 136 ? -29.72186 37.62370 -47.20686 1.000 28.44250 ? 137 TYR B CD1 1 
ATOM   3299 C CD2 . TYR B 1 136 ? -29.91163 39.87265 -47.98441 1.000 31.51537 ? 137 TYR B CD2 1 
ATOM   3300 C CE1 . TYR B 1 136 ? -31.09855 37.50489 -47.20163 1.000 31.21917 ? 137 TYR B CE1 1 
ATOM   3301 C CE2 . TYR B 1 136 ? -31.28991 39.75894 -47.98760 1.000 32.26176 ? 137 TYR B CE2 1 
ATOM   3302 C CZ  . TYR B 1 136 ? -31.87068 38.57255 -47.59280 1.000 31.64261 ? 137 TYR B CZ  1 
ATOM   3303 O OH  . TYR B 1 136 ? -33.23917 38.44016 -47.57818 1.000 43.49478 ? 137 TYR B OH  1 
ATOM   3304 N N   . THR B 1 137 ? -24.98072 39.43794 -45.01397 1.000 28.80273 ? 138 THR B N   1 
ATOM   3305 C CA  . THR B 1 137 ? -23.59801 39.14827 -44.67194 1.000 27.02821 ? 138 THR B CA  1 
ATOM   3306 C C   . THR B 1 137 ? -23.58626 38.47721 -43.30567 1.000 28.27830 ? 138 THR B C   1 
ATOM   3307 O O   . THR B 1 137 ? -24.60624 38.42329 -42.60928 1.000 27.86452 ? 138 THR B O   1 
ATOM   3308 C CB  . THR B 1 137 ? -22.73004 40.41490 -44.65489 1.000 29.71031 ? 138 THR B CB  1 
ATOM   3309 O OG1 . THR B 1 137 ? -23.15854 41.27412 -43.59086 1.000 27.50401 ? 138 THR B OG1 1 
ATOM   3310 C CG2 . THR B 1 137 ? -22.84377 41.18421 -45.97946 1.000 31.01893 ? 138 THR B CG2 1 
ATOM   3311 N N   . ILE B 1 138 ? -22.43218 37.93953 -42.91652 1.000 23.97944 ? 139 ILE B N   1 
ATOM   3312 C CA  . ILE B 1 138 ? -22.27520 37.47548 -41.54102 1.000 23.40947 ? 139 ILE B CA  1 
ATOM   3313 C C   . ILE B 1 138 ? -20.99746 38.04874 -40.95169 1.000 26.72536 ? 139 ILE B C   1 
ATOM   3314 O O   . ILE B 1 138 ? -20.04144 38.36763 -41.66672 1.000 27.20371 ? 139 ILE B O   1 
ATOM   3315 C CB  . ILE B 1 138 ? -22.27706 35.93505 -41.40719 1.000 23.03885 ? 139 ILE B CB  1 
ATOM   3316 C CG1 . ILE B 1 138 ? -21.16034 35.29859 -42.24477 1.000 23.55685 ? 139 ILE B CG1 1 
ATOM   3317 C CG2 . ILE B 1 138 ? -23.63716 35.36354 -41.77160 1.000 23.84032 ? 139 ILE B CG2 1 
ATOM   3318 C CD1 . ILE B 1 138 ? -21.09865 33.77534 -42.08248 1.000 25.00314 ? 139 ILE B CD1 1 
ATOM   3319 N N   . LYS B 1 139 ? -20.99553 38.17985 -39.62458 1.000 22.82719 ? 140 LYS B N   1 
ATOM   3320 C CA  . LYS B 1 139 ? -19.86591 38.72452 -38.87916 1.000 26.38036 ? 140 LYS B CA  1 
ATOM   3321 C C   . LYS B 1 139 ? -19.08235 37.53342 -38.33882 1.000 26.62340 ? 140 LYS B C   1 
ATOM   3322 O O   . LYS B 1 139 ? -19.18864 37.14824 -37.17430 1.000 27.80339 ? 140 LYS B O   1 
ATOM   3323 C CB  . LYS B 1 139 ? -20.35213 39.65510 -37.76483 1.000 24.21243 ? 140 LYS B CB  1 
ATOM   3324 C CG  . LYS B 1 139 ? -21.39852 40.67122 -38.22456 1.000 27.95026 ? 140 LYS B CG  1 
ATOM   3325 C CD  . LYS B 1 139 ? -21.77698 41.66438 -37.11922 1.000 31.86719 ? 140 LYS B CD  1 
ATOM   3326 C CE  . LYS B 1 139 ? -22.58094 42.84742 -37.65802 1.000 36.19364 ? 140 LYS B CE  1 
ATOM   3327 N NZ  . LYS B 1 139 ? -22.95338 43.80389 -36.56195 1.000 38.43976 ? 140 LYS B NZ  1 
ATOM   3328 N N   . GLY B 1 140 ? -18.30753 36.91854 -39.21698 1.000 24.68187 ? 141 GLY B N   1 
ATOM   3329 C CA  . GLY B 1 140 ? -17.57698 35.72692 -38.85142 1.000 28.58559 ? 141 GLY B CA  1 
ATOM   3330 C C   . GLY B 1 140 ? -16.16685 36.04241 -38.40954 1.000 28.02706 ? 141 GLY B C   1 
ATOM   3331 O O   . GLY B 1 140 ? -15.73254 37.19190 -38.37063 1.000 26.06592 ? 141 GLY B O   1 
ATOM   3332 N N   . SER B 1 141 ? -15.44066 34.98729 -38.06315 1.000 26.43949 ? 142 SER B N   1 
ATOM   3333 C CA  . SER B 1 141 ? -13.99723 35.06951 -37.88771 1.000 26.29748 ? 142 SER B CA  1 
ATOM   3334 C C   . SER B 1 141 ? -13.41032 34.10016 -38.91014 1.000 25.23231 ? 142 SER B C   1 
ATOM   3335 O O   . SER B 1 141 ? -13.33533 32.89220 -38.66629 1.000 25.06330 ? 142 SER B O   1 
ATOM   3336 C CB  . SER B 1 141 ? -13.58314 34.74593 -36.45580 1.000 29.94345 ? 142 SER B CB  1 
ATOM   3337 O OG  . SER B 1 141 ? -12.18990 34.92921 -36.28628 1.000 29.73962 ? 142 SER B OG  1 
ATOM   3338 N N   . PHE B 1 142 ? -13.04599 34.63493 -40.07707 1.000 26.02635 ? 143 PHE B N   1 
ATOM   3339 C CA  . PHE B 1 142 ? -12.55838 33.86632 -41.21933 1.000 24.97537 ? 143 PHE B CA  1 
ATOM   3340 C C   . PHE B 1 142 ? -11.28466 34.52574 -41.71840 1.000 28.97203 ? 143 PHE B C   1 
ATOM   3341 O O   . PHE B 1 142 ? -11.28142 35.73455 -41.98981 1.000 32.21052 ? 143 PHE B O   1 
ATOM   3342 C CB  . PHE B 1 142 ? -13.54682 33.86675 -42.37641 1.000 24.14478 ? 143 PHE B CB  1 
ATOM   3343 C CG  . PHE B 1 142 ? -14.76384 33.01805 -42.18375 1.000 26.36590 ? 143 PHE B CG  1 
ATOM   3344 C CD1 . PHE B 1 142 ? -14.66745 31.64739 -42.00018 1.000 28.37653 ? 143 PHE B CD1 1 
ATOM   3345 C CD2 . PHE B 1 142 ? -16.00927 33.58348 -42.26581 1.000 26.34679 ? 143 PHE B CD2 1 
ATOM   3346 C CE1 . PHE B 1 142 ? -15.80429 30.88321 -41.86619 1.000 26.17878 ? 143 PHE B CE1 1 
ATOM   3347 C CE2 . PHE B 1 142 ? -17.15058 32.81689 -42.13819 1.000 28.65482 ? 143 PHE B CE2 1 
ATOM   3348 C CZ  . PHE B 1 142 ? -17.05619 31.48307 -41.95837 1.000 23.85510 ? 143 PHE B CZ  1 
ATOM   3349 N N   . LEU B 1 143 ? -10.22328 33.74650 -41.85454 1.000 25.70865 ? 144 LEU B N   1 
ATOM   3350 C CA  . LEU B 1 143 ? -8.95902  34.21878 -42.39855 1.000 28.99739 ? 144 LEU B CA  1 
ATOM   3351 C C   . LEU B 1 143 ? -8.78550  33.69037 -43.82764 1.000 29.73764 ? 144 LEU B C   1 
ATOM   3352 O O   . LEU B 1 143 ? -9.62675  32.95947 -44.34968 1.000 27.04882 ? 144 LEU B O   1 
ATOM   3353 C CB  . LEU B 1 143 ? -7.80693  33.78554 -41.49592 1.000 30.63810 ? 144 LEU B CB  1 
ATOM   3354 C CG  . LEU B 1 143 ? -7.83270  34.41847 -40.09891 1.000 34.88678 ? 144 LEU B CG  1 
ATOM   3355 C CD1 . LEU B 1 143 ? -6.68613  33.90964 -39.25714 1.000 39.63231 ? 144 LEU B CD1 1 
ATOM   3356 C CD2 . LEU B 1 143 ? -7.77975  35.92887 -40.21689 1.000 33.45874 ? 144 LEU B CD2 1 
ATOM   3357 N N   . CYS B 1 144 ? -7.67864  34.06803 -44.46926 1.000 29.76110 ? 145 CYS B N   1 
ATOM   3358 C CA  . CYS B 1 144 ? -7.42363  33.60642 -45.83012 1.000 29.56059 ? 145 CYS B CA  1 
ATOM   3359 C C   . CYS B 1 144 ? -7.40570  32.08074 -45.89866 1.000 28.04366 ? 145 CYS B C   1 
ATOM   3360 O O   . CYS B 1 144 ? -6.81945  31.40972 -45.04715 1.000 24.33430 ? 145 CYS B O   1 
ATOM   3361 C CB  . CYS B 1 144 ? -6.09224  34.16534 -46.33685 1.000 33.95225 ? 145 CYS B CB  1 
ATOM   3362 S SG  . CYS B 1 144 ? -6.18381  35.91289 -46.74136 1.000 47.79414 ? 145 CYS B SG  1 
ATOM   3363 N N   . GLY B 1 145 ? -8.04604  31.53355 -46.93147 1.000 27.26720 ? 146 GLY B N   1 
ATOM   3364 C CA  . GLY B 1 145 ? -8.13577  30.09723 -47.07945 1.000 28.86650 ? 146 GLY B CA  1 
ATOM   3365 C C   . GLY B 1 145 ? -9.33174  29.45347 -46.40666 1.000 27.16887 ? 146 GLY B C   1 
ATOM   3366 O O   . GLY B 1 145 ? -9.47810  28.22540 -46.47516 1.000 28.67892 ? 146 GLY B O   1 
ATOM   3367 N N   . SER B 1 146 ? -10.19007 30.23569 -45.76470 1.000 26.22043 ? 147 SER B N   1 
ATOM   3368 C CA  . SER B 1 146 ? -11.36869 29.69163 -45.10567 1.000 25.46202 ? 147 SER B CA  1 
ATOM   3369 C C   . SER B 1 146 ? -12.51389 29.39601 -46.06451 1.000 23.74616 ? 147 SER B C   1 
ATOM   3370 O O   . SER B 1 146 ? -13.49762 28.78306 -45.63965 1.000 22.34960 ? 147 SER B O   1 
ATOM   3371 C CB  . SER B 1 146 ? -11.83413 30.66543 -44.02838 1.000 26.61750 ? 147 SER B CB  1 
ATOM   3372 O OG  . SER B 1 146 ? -12.02169 31.94257 -44.59912 1.000 28.58710 ? 147 SER B OG  1 
ATOM   3373 N N   . ALA B 1 147 ? -12.42405 29.84072 -47.32457 1.000 22.79381 ? 148 ALA B N   1 
ATOM   3374 C CA  . ALA B 1 147 ? -13.45122 29.53860 -48.32012 1.000 23.85231 ? 148 ALA B CA  1 
ATOM   3375 C C   . ALA B 1 147 ? -13.78175 28.04566 -48.34573 1.000 20.84927 ? 148 ALA B C   1 
ATOM   3376 O O   . ALA B 1 147 ? -12.89473 27.19287 -48.27039 1.000 20.47145 ? 148 ALA B O   1 
ATOM   3377 C CB  . ALA B 1 147 ? -12.98556 30.01808 -49.70535 1.000 30.71291 ? 148 ALA B CB  1 
ATOM   3378 N N   . GLY B 1 148 ? -15.07572 27.73535 -48.42407 1.000 19.85374 ? 149 GLY B N   1 
ATOM   3379 C CA  . GLY B 1 148 ? -15.55630 26.37220 -48.36212 1.000 20.43439 ? 149 GLY B CA  1 
ATOM   3380 C C   . GLY B 1 148 ? -15.95600 25.91857 -46.97511 1.000 21.41747 ? 149 GLY B C   1 
ATOM   3381 O O   . GLY B 1 148 ? -16.63821 24.89122 -46.84807 1.000 23.11765 ? 149 GLY B O   1 
ATOM   3382 N N   . SER B 1 149 ? -15.57082 26.66221 -45.93480 1.000 20.83386 ? 150 SER B N   1 
ATOM   3383 C CA  . SER B 1 149 ? -16.06581 26.37795 -44.59929 1.000 20.62599 ? 150 SER B CA  1 
ATOM   3384 C C   . SER B 1 149 ? -17.58649 26.39546 -44.62358 1.000 22.63133 ? 150 SER B C   1 
ATOM   3385 O O   . SER B 1 149 ? -18.20814 27.10290 -45.41903 1.000 24.11732 ? 150 SER B O   1 
ATOM   3386 C CB  . SER B 1 149 ? -15.53562 27.41248 -43.59794 1.000 22.67699 ? 150 SER B CB  1 
ATOM   3387 O OG  . SER B 1 149 ? -14.12767 27.29620 -43.43001 1.000 23.37090 ? 150 SER B OG  1 
ATOM   3388 N N   . VAL B 1 150 ? -18.19627 25.62134 -43.74398 1.000 18.38700 ? 151 VAL B N   1 
ATOM   3389 C CA  . VAL B 1 150 ? -19.61398 25.33403 -43.85908 1.000 20.36452 ? 151 VAL B CA  1 
ATOM   3390 C C   . VAL B 1 150 ? -20.35145 25.80229 -42.60974 1.000 22.78750 ? 151 VAL B C   1 
ATOM   3391 O O   . VAL B 1 150 ? -19.83398 25.69961 -41.49533 1.000 20.71752 ? 151 VAL B O   1 
ATOM   3392 C CB  . VAL B 1 150 ? -19.80185 23.82465 -44.11958 1.000 27.64448 ? 151 VAL B CB  1 
ATOM   3393 C CG1 . VAL B 1 150 ? -21.17972 23.39661 -43.80205 1.000 28.18174 ? 151 VAL B CG1 1 
ATOM   3394 C CG2 . VAL B 1 150 ? -19.43710 23.52610 -45.56186 1.000 22.87837 ? 151 VAL B CG2 1 
ATOM   3395 N N   . GLY B 1 151 ? -21.55578 26.33789 -42.80943 1.000 22.97540 ? 152 GLY B N   1 
ATOM   3396 C CA  . GLY B 1 151 ? -22.47557 26.64116 -41.72741 1.000 22.85807 ? 152 GLY B CA  1 
ATOM   3397 C C   . GLY B 1 151 ? -23.70187 25.74566 -41.76409 1.000 21.08819 ? 152 GLY B C   1 
ATOM   3398 O O   . GLY B 1 151 ? -24.11918 25.28303 -42.83334 1.000 20.66979 ? 152 GLY B O   1 
ATOM   3399 N N   . TYR B 1 152 ? -24.30143 25.51666 -40.59678 1.000 21.18484 ? 153 TYR B N   1 
ATOM   3400 C CA  . TYR B 1 152 ? -25.33447 24.48990 -40.50185 1.000 23.94776 ? 153 TYR B CA  1 
ATOM   3401 C C   . TYR B 1 152 ? -26.10036 24.64358 -39.20116 1.000 22.85034 ? 153 TYR B C   1 
ATOM   3402 O O   . TYR B 1 152 ? -25.62221 25.23956 -38.22714 1.000 23.51884 ? 153 TYR B O   1 
ATOM   3403 C CB  . TYR B 1 152 ? -24.74504 23.06549 -40.57678 1.000 23.86146 ? 153 TYR B CB  1 
ATOM   3404 C CG  . TYR B 1 152 ? -23.64612 22.87299 -39.54915 1.000 21.17096 ? 153 TYR B CG  1 
ATOM   3405 C CD1 . TYR B 1 152 ? -22.36000 23.28385 -39.83007 1.000 22.39039 ? 153 TYR B CD1 1 
ATOM   3406 C CD2 . TYR B 1 152 ? -23.90659 22.33520 -38.28844 1.000 24.51189 ? 153 TYR B CD2 1 
ATOM   3407 C CE1 . TYR B 1 152 ? -21.35309 23.15606 -38.90640 1.000 27.94071 ? 153 TYR B CE1 1 
ATOM   3408 C CE2 . TYR B 1 152 ? -22.88937 22.20449 -37.34418 1.000 25.13900 ? 153 TYR B CE2 1 
ATOM   3409 C CZ  . TYR B 1 152 ? -21.61263 22.62978 -37.67738 1.000 27.44983 ? 153 TYR B CZ  1 
ATOM   3410 O OH  . TYR B 1 152 ? -20.54866 22.52724 -36.80105 1.000 37.04558 ? 153 TYR B OH  1 
ATOM   3411 N N   . THR B 1 153 ? -27.29915 24.08025 -39.20616 1.000 25.17742 ? 154 THR B N   1 
ATOM   3412 C CA  . THR B 1 153 ? -28.10666 23.84563 -38.02411 1.000 29.61556 ? 154 THR B CA  1 
ATOM   3413 C C   . THR B 1 153 ? -28.37641 22.35031 -37.93646 1.000 31.26226 ? 154 THR B C   1 
ATOM   3414 O O   . THR B 1 153 ? -28.09156 21.59411 -38.86438 1.000 28.73768 ? 154 THR B O   1 
ATOM   3415 C CB  . THR B 1 153 ? -29.42509 24.63570 -38.07571 1.000 26.80818 ? 154 THR B CB  1 
ATOM   3416 O OG1 . THR B 1 153 ? -30.22792 24.15673 -39.15427 1.000 30.60003 ? 154 THR B OG1 1 
ATOM   3417 C CG2 . THR B 1 153 ? -29.16462 26.12581 -38.29718 1.000 27.77241 ? 154 THR B CG2 1 
ATOM   3418 N N   . LYS B 1 154 ? -28.90770 21.92724 -36.79860 1.000 30.03833 ? 155 LYS B N   1 
ATOM   3419 C CA  . LYS B 1 154 ? -29.26846 20.53945 -36.55618 1.000 31.75662 ? 155 LYS B CA  1 
ATOM   3420 C C   . LYS B 1 154 ? -30.65369 20.50748 -35.93637 1.000 40.47396 ? 155 LYS B C   1 
ATOM   3421 O O   . LYS B 1 154 ? -30.99207 21.37398 -35.12428 1.000 38.86257 ? 155 LYS B O   1 
ATOM   3422 C CB  . LYS B 1 154 ? -28.29900 19.84061 -35.60685 1.000 33.81686 ? 155 LYS B CB  1 
ATOM   3423 C CG  . LYS B 1 154 ? -26.87927 19.71788 -36.08571 1.000 36.32416 ? 155 LYS B CG  1 
ATOM   3424 C CD  . LYS B 1 154 ? -26.23139 18.44621 -35.50928 1.000 41.05040 ? 155 LYS B CD  1 
ATOM   3425 C CE  . LYS B 1 154 ? -24.78918 18.69742 -35.06225 1.000 39.77601 ? 155 LYS B CE  1 
ATOM   3426 N NZ  . LYS B 1 154 ? -23.85583 17.58091 -35.42822 1.000 40.33635 ? 155 LYS B NZ  1 
ATOM   3427 N N   . GLU B 1 155 ? -31.45366 19.51301 -36.32315 1.000 40.34213 ? 156 GLU B N   1 
ATOM   3428 C CA  . GLU B 1 155 ? -32.73103 19.25053 -35.66827 1.000 45.42655 ? 156 GLU B CA  1 
ATOM   3429 C C   . GLU B 1 155 ? -32.87266 17.74238 -35.56261 1.000 45.43319 ? 156 GLU B C   1 
ATOM   3430 O O   . GLU B 1 155 ? -32.83400 17.04324 -36.58137 1.000 47.40887 ? 156 GLU B O   1 
ATOM   3431 C CB  . GLU B 1 155 ? -33.90368 19.88153 -36.43274 1.000 49.03497 ? 156 GLU B CB  1 
ATOM   3432 C CG  . GLU B 1 155 ? -33.80612 19.77431 -37.95779 1.000 50.38665 ? 156 GLU B CG  1 
ATOM   3433 C CD  . GLU B 1 155 ? -34.75577 18.72968 -38.54153 1.000 59.56738 ? 156 GLU B CD  1 
ATOM   3434 O OE1 . GLU B 1 155 ? -34.90141 18.65990 -39.78852 1.000 59.72292 ? 156 GLU B OE1 1 
ATOM   3435 O OE2 . GLU B 1 155 ? -35.35802 17.97371 -37.74805 1.000 64.00836 ? 156 GLU B OE2 1 
ATOM   3436 N N   . GLY B 1 156 ? -33.00854 17.24585 -34.34298 1.000 46.45680 ? 157 GLY B N   1 
ATOM   3437 C CA  . GLY B 1 156 ? -32.86682 15.81801 -34.14305 1.000 46.95285 ? 157 GLY B CA  1 
ATOM   3438 C C   . GLY B 1 156 ? -31.47207 15.41770 -34.56567 1.000 49.32561 ? 157 GLY B C   1 
ATOM   3439 O O   . GLY B 1 156 ? -30.47271 15.98330 -34.11139 1.000 52.26203 ? 157 GLY B O   1 
ATOM   3440 N N   . SER B 1 157 ? -31.38303 14.45940 -35.47872 1.000 48.80737 ? 158 SER B N   1 
ATOM   3441 C CA  . SER B 1 157 ? -30.10162 14.03764 -36.01881 1.000 49.66808 ? 158 SER B CA  1 
ATOM   3442 C C   . SER B 1 157 ? -29.87739 14.52088 -37.44616 1.000 43.86949 ? 158 SER B C   1 
ATOM   3443 O O   . SER B 1 157 ? -28.88129 14.13015 -38.06665 1.000 44.41203 ? 158 SER B O   1 
ATOM   3444 C CB  . SER B 1 157 ? -29.98439 12.51740 -35.95641 1.000 50.42208 ? 158 SER B CB  1 
ATOM   3445 O OG  . SER B 1 157 ? -31.15272 11.92018 -36.49377 1.000 59.87379 ? 158 SER B OG  1 
ATOM   3446 N N   . VAL B 1 158 ? -30.76703 15.36544 -37.97795 1.000 36.27478 ? 159 VAL B N   1 
ATOM   3447 C CA  . VAL B 1 158 ? -30.63725 15.87521 -39.34122 1.000 35.53626 ? 159 VAL B CA  1 
ATOM   3448 C C   . VAL B 1 158 ? -29.86000 17.18831 -39.32549 1.000 38.32861 ? 159 VAL B C   1 
ATOM   3449 O O   . VAL B 1 158 ? -30.21733 18.12337 -38.60287 1.000 35.53329 ? 159 VAL B O   1 
ATOM   3450 C CB  . VAL B 1 158 ? -32.01413 16.06566 -39.99074 1.000 37.87326 ? 159 VAL B CB  1 
ATOM   3451 C CG1 . VAL B 1 158 ? -31.84659 16.46779 -41.44571 1.000 37.06972 ? 159 VAL B CG1 1 
ATOM   3452 C CG2 . VAL B 1 158 ? -32.84221 14.79370 -39.86437 1.000 42.86137 ? 159 VAL B CG2 1 
ATOM   3453 N N   . ILE B 1 159 ? -28.80051 17.26203 -40.13052 1.000 32.53477 ? 160 ILE B N   1 
ATOM   3454 C CA  . ILE B 1 159 ? -28.00743 18.48055 -40.28037 1.000 33.52145 ? 160 ILE B CA  1 
ATOM   3455 C C   . ILE B 1 159 ? -28.53966 19.26742 -41.46991 1.000 31.83039 ? 160 ILE B C   1 
ATOM   3456 O O   . ILE B 1 159 ? -28.61627 18.74268 -42.58769 1.000 28.42033 ? 160 ILE B O   1 
ATOM   3457 C CB  . ILE B 1 159 ? -26.52036 18.14717 -40.47455 1.000 29.05499 ? 160 ILE B CB  1 
ATOM   3458 C CG1 . ILE B 1 159 ? -25.97312 17.44754 -39.24026 1.000 32.41357 ? 160 ILE B CG1 1 
ATOM   3459 C CG2 . ILE B 1 159 ? -25.71080 19.40961 -40.78413 1.000 27.44308 ? 160 ILE B CG2 1 
ATOM   3460 C CD1 . ILE B 1 159 ? -24.55643 16.99562 -39.40617 1.000 34.92475 ? 160 ILE B CD1 1 
ATOM   3461 N N   . ASN B 1 160 ? -28.88677 20.53091 -41.24949 1.000 26.81173 ? 161 ASN B N   1 
ATOM   3462 C CA  . ASN B 1 160 ? -29.25422 21.40761 -42.35513 1.000 28.10643 ? 161 ASN B CA  1 
ATOM   3463 C C   . ASN B 1 160 ? -28.06019 22.27336 -42.73214 1.000 29.47825 ? 161 ASN B C   1 
ATOM   3464 O O   . ASN B 1 160 ? -27.73145 23.23058 -42.02847 1.000 24.71842 ? 161 ASN B O   1 
ATOM   3465 C CB  . ASN B 1 160 ? -30.45580 22.28318 -42.02426 1.000 30.97787 ? 161 ASN B CB  1 
ATOM   3466 C CG  . ASN B 1 160 ? -30.90519 23.07545 -43.23665 1.000 36.84210 ? 161 ASN B CG  1 
ATOM   3467 O OD1 . ASN B 1 160 ? -31.39176 22.49240 -44.20841 1.000 39.21695 ? 161 ASN B OD1 1 
ATOM   3468 N ND2 . ASN B 1 160 ? -30.69958 24.39604 -43.21507 1.000 38.72147 ? 161 ASN B ND2 1 
ATOM   3469 N N   . PHE B 1 161 ? -27.42451 21.94938 -43.85859 1.000 25.70617 ? 162 PHE B N   1 
ATOM   3470 C CA  . PHE B 1 161 ? -26.34690 22.77237 -44.38747 1.000 24.94283 ? 162 PHE B CA  1 
ATOM   3471 C C   . PHE B 1 161 ? -26.94580 23.99839 -45.07404 1.000 29.01891 ? 162 PHE B C   1 
ATOM   3472 O O   . PHE B 1 161 ? -27.72883 23.85988 -46.01812 1.000 30.90533 ? 162 PHE B O   1 
ATOM   3473 C CB  . PHE B 1 161 ? -25.49602 21.95232 -45.35738 1.000 23.99443 ? 162 PHE B CB  1 
ATOM   3474 C CG  . PHE B 1 161 ? -24.75312 20.82435 -44.69381 1.000 22.95580 ? 162 PHE B CG  1 
ATOM   3475 C CD1 . PHE B 1 161 ? -23.65683 21.08625 -43.87871 1.000 22.93010 ? 162 PHE B CD1 1 
ATOM   3476 C CD2 . PHE B 1 161 ? -25.13975 19.51071 -44.88042 1.000 23.17357 ? 162 PHE B CD2 1 
ATOM   3477 C CE1 . PHE B 1 161 ? -22.95977 20.05633 -43.26375 1.000 23.88554 ? 162 PHE B CE1 1 
ATOM   3478 C CE2 . PHE B 1 161 ? -24.44569 18.47007 -44.26315 1.000 23.90547 ? 162 PHE B CE2 1 
ATOM   3479 C CZ  . PHE B 1 161 ? -23.34978 18.75104 -43.46005 1.000 24.48146 ? 162 PHE B CZ  1 
ATOM   3480 N N   . CYS B 1 162 ? -26.57916 25.19786 -44.60421 1.000 26.56394 ? 163 CYS B N   1 
ATOM   3481 C CA  . CYS B 1 162 ? -27.17702 26.44228 -45.08532 1.000 24.86763 ? 163 CYS B CA  1 
ATOM   3482 C C   . CYS B 1 162 ? -26.17709 27.46575 -45.59937 1.000 22.90879 ? 163 CYS B C   1 
ATOM   3483 O O   . CYS B 1 162 ? -26.59372 28.47454 -46.17756 1.000 25.74889 ? 163 CYS B O   1 
ATOM   3484 C CB  . CYS B 1 162 ? -28.01334 27.08661 -43.96612 1.000 25.26830 ? 163 CYS B CB  1 
ATOM   3485 S SG  . CYS B 1 162 ? -27.03850 27.48160 -42.46945 1.000 28.96774 ? 163 CYS B SG  1 
ATOM   3486 N N   . TYR B 1 163 ? -24.87937 27.23141 -45.44780 1.000 20.76219 ? 164 TYR B N   1 
ATOM   3487 C CA  . TYR B 1 163 ? -23.89052 28.24196 -45.77462 1.000 21.66902 ? 164 TYR B CA  1 
ATOM   3488 C C   . TYR B 1 163 ? -22.58814 27.57683 -46.18438 1.000 23.13085 ? 164 TYR B C   1 
ATOM   3489 O O   . TYR B 1 163 ? -22.10581 26.67873 -45.48601 1.000 21.93636 ? 164 TYR B O   1 
ATOM   3490 C CB  . TYR B 1 163 ? -23.65424 29.15419 -44.56162 1.000 21.14393 ? 164 TYR B CB  1 
ATOM   3491 C CG  . TYR B 1 163 ? -22.66393 30.27214 -44.77612 1.000 22.15190 ? 164 TYR B CG  1 
ATOM   3492 C CD1 . TYR B 1 163 ? -21.32068 30.10327 -44.47785 1.000 21.88035 ? 164 TYR B CD1 1 
ATOM   3493 C CD2 . TYR B 1 163 ? -23.07881 31.51396 -45.25233 1.000 25.08764 ? 164 TYR B CD2 1 
ATOM   3494 C CE1 . TYR B 1 163 ? -20.41575 31.13513 -44.66259 1.000 19.55566 ? 164 TYR B CE1 1 
ATOM   3495 C CE2 . TYR B 1 163 ? -22.18396 32.54136 -45.43906 1.000 21.37207 ? 164 TYR B CE2 1 
ATOM   3496 C CZ  . TYR B 1 163 ? -20.85498 32.34422 -45.14542 1.000 23.83118 ? 164 TYR B CZ  1 
ATOM   3497 O OH  . TYR B 1 163 ? -19.95956 33.36964 -45.33482 1.000 22.23328 ? 164 TYR B OH  1 
ATOM   3498 N N   . MET B 1 164 ? -22.01611 28.02696 -47.29853 1.000 22.11923 ? 165 MET B N   1 
ATOM   3499 C CA  . MET B 1 164 ? -20.64772 27.67829 -47.65666 1.000 23.49360 ? 165 MET B CA  1 
ATOM   3500 C C   . MET B 1 164 ? -19.88546 28.96427 -47.92027 1.000 23.34886 ? 165 MET B C   1 
ATOM   3501 O O   . MET B 1 164 ? -20.27256 29.75666 -48.78684 1.000 22.55734 ? 165 MET B O   1 
ATOM   3502 C CB  . MET B 1 164 ? -20.59073 26.74587 -48.87240 1.000 25.51668 ? 165 MET B CB  1 
ATOM   3503 C CG  . MET B 1 164 ? -19.16058 26.48977 -49.29971 1.000 23.34189 ? 165 MET B CG  1 
ATOM   3504 S SD  . MET B 1 164 ? -18.94443 25.06500 -50.37748 1.000 25.14551 ? 165 MET B SD  1 
ATOM   3505 C CE  . MET B 1 164 ? -18.92367 23.72509 -49.19074 1.000 19.02299 ? 165 MET B CE  1 
ATOM   3506 N N   . HIS B 1 165 ? -18.80228 29.17443 -47.17439 1.000 21.73975 ? 166 HIS B N   1 
ATOM   3507 C CA  . HIS B 1 165 ? -18.14781 30.47237 -47.17282 1.000 21.86159 ? 166 HIS B CA  1 
ATOM   3508 C C   . HIS B 1 165 ? -17.50644 30.79065 -48.52294 1.000 24.77867 ? 166 HIS B C   1 
ATOM   3509 O O   . HIS B 1 165 ? -16.85694 29.93918 -49.13520 1.000 22.29630 ? 166 HIS B O   1 
ATOM   3510 C CB  . HIS B 1 165 ? -17.09085 30.52931 -46.06908 1.000 22.17380 ? 166 HIS B CB  1 
ATOM   3511 C CG  . HIS B 1 165 ? -16.43118 31.86407 -45.98158 1.000 20.91160 ? 166 HIS B CG  1 
ATOM   3512 N ND1 . HIS B 1 165 ? -17.15755 33.03373 -45.93232 1.000 22.72749 ? 166 HIS B ND1 1 
ATOM   3513 C CD2 . HIS B 1 165 ? -15.12833 32.22711 -46.02383 1.000 21.68525 ? 166 HIS B CD2 1 
ATOM   3514 C CE1 . HIS B 1 165 ? -16.32838 34.06294 -45.91956 1.000 24.27842 ? 166 HIS B CE1 1 
ATOM   3515 N NE2 . HIS B 1 165 ? -15.09113 33.60204 -45.96647 1.000 23.11261 ? 166 HIS B NE2 1 
ATOM   3516 N N   . GLN B 1 166 ? -17.67728 32.03677 -48.98041 1.000 24.01228 ? 167 GLN B N   1 
ATOM   3517 C CA  . GLN B 1 166 ? -17.18912 32.44983 -50.29476 1.000 25.92399 ? 167 GLN B CA  1 
ATOM   3518 C C   . GLN B 1 166 ? -16.14914 33.55823 -50.24233 1.000 24.82733 ? 167 GLN B C   1 
ATOM   3519 O O   . GLN B 1 166 ? -15.08981 33.42734 -50.87601 1.000 28.33260 ? 167 GLN B O   1 
ATOM   3520 C CB  . GLN B 1 166 ? -18.35421 32.88740 -51.19506 1.000 25.48446 ? 167 GLN B CB  1 
ATOM   3521 C CG  . GLN B 1 166 ? -19.23602 31.75742 -51.67917 1.000 26.28420 ? 167 GLN B CG  1 
ATOM   3522 C CD  . GLN B 1 166 ? -18.77094 31.14637 -52.99375 1.000 27.21537 ? 167 GLN B CD  1 
ATOM   3523 O OE1 . GLN B 1 166 ? -17.70967 31.48767 -53.52237 1.000 29.55262 ? 167 GLN B OE1 1 
ATOM   3524 N NE2 . GLN B 1 166 ? -19.57018 30.23345 -53.52385 1.000 28.12199 ? 167 GLN B NE2 1 
ATOM   3525 N N   . MET B 1 167 ? -16.39460 34.65306 -49.51476 1.000 24.95379 ? 168 MET B N   1 
ATOM   3526 C CA  . MET B 1 167 ? -15.48931 35.78786 -49.65887 1.000 28.66425 ? 168 MET B CA  1 
ATOM   3527 C C   . MET B 1 167 ? -15.62635 36.76606 -48.49948 1.000 26.99713 ? 168 MET B C   1 
ATOM   3528 O O   . MET B 1 167 ? -16.64268 36.80472 -47.80508 1.000 22.91656 ? 168 MET B O   1 
ATOM   3529 C CB  . MET B 1 167 ? -15.74934 36.53067 -50.97796 1.000 30.07105 ? 168 MET B CB  1 
ATOM   3530 C CG  . MET B 1 167 ? -17.20107 36.92174 -51.14048 1.000 32.51830 ? 168 MET B CG  1 
ATOM   3531 S SD  . MET B 1 167 ? -17.54407 37.51773 -52.81295 1.000 46.81296 ? 168 MET B SD  1 
ATOM   3532 C CE  . MET B 1 167 ? -16.06010 38.48989 -53.09916 1.000 38.92274 ? 168 MET B CE  1 
ATOM   3533 N N   . GLU B 1 168 ? -14.59583 37.59071 -48.33979 1.000 27.71222 ? 169 GLU B N   1 
ATOM   3534 C CA  . GLU B 1 168 ? -14.60343 38.67668 -47.36990 1.000 29.87032 ? 169 GLU B CA  1 
ATOM   3535 C C   . GLU B 1 168 ? -14.85289 39.99240 -48.10795 1.000 36.04722 ? 169 GLU B C   1 
ATOM   3536 O O   . GLU B 1 168 ? -14.20780 40.26762 -49.13025 1.000 31.70665 ? 169 GLU B O   1 
ATOM   3537 C CB  . GLU B 1 168 ? -13.28618 38.71989 -46.58951 1.000 31.06346 ? 169 GLU B CB  1 
ATOM   3538 C CG  . GLU B 1 168 ? -13.25810 39.77502 -45.46526 1.000 33.45374 ? 169 GLU B CG  1 
ATOM   3539 C CD  . GLU B 1 168 ? -12.11172 39.58647 -44.46432 1.000 43.07072 ? 169 GLU B CD  1 
ATOM   3540 O OE1 . GLU B 1 168 ? -12.16455 38.64415 -43.62676 1.000 40.93008 ? 169 GLU B OE1 1 
ATOM   3541 O OE2 . GLU B 1 168 ? -11.15792 40.39986 -44.50392 1.000 42.79288 ? 169 GLU B OE2 1 
ATOM   3542 N N   . LEU B 1 169 ? -15.81701 40.77461 -47.61450 1.000 33.77342 ? 170 LEU B N   1 
ATOM   3543 C CA  . LEU B 1 169 ? -16.15159 42.07564 -48.18033 1.000 41.74539 ? 170 LEU B CA  1 
ATOM   3544 C C   . LEU B 1 169 ? -15.26858 43.17511 -47.57812 1.000 40.21929 ? 170 LEU B C   1 
ATOM   3545 O O   . LEU B 1 169 ? -14.54042 42.96450 -46.60390 1.000 34.11615 ? 170 LEU B O   1 
ATOM   3546 C CB  . LEU B 1 169 ? -17.63255 42.39455 -47.96362 1.000 41.44768 ? 170 LEU B CB  1 
ATOM   3547 C CG  . LEU B 1 169 ? -18.63379 41.42614 -48.59483 1.000 39.78747 ? 170 LEU B CG  1 
ATOM   3548 C CD1 . LEU B 1 169 ? -20.05930 41.83804 -48.30205 1.000 43.12481 ? 170 LEU B CD1 1 
ATOM   3549 C CD2 . LEU B 1 169 ? -18.41523 41.32482 -50.09858 1.000 41.34096 ? 170 LEU B CD2 1 
ATOM   3550 N N   . ALA B 1 170 ? -15.34625 44.37324 -48.17514 1.000 42.66674 ? 171 ALA B N   1 
ATOM   3551 C CA  . ALA B 1 170 ? -14.39761 45.44037 -47.84714 1.000 46.20262 ? 171 ALA B CA  1 
ATOM   3552 C C   . ALA B 1 170 ? -14.46049 45.85542 -46.37755 1.000 49.85667 ? 171 ALA B C   1 
ATOM   3553 O O   . ALA B 1 170 ? -13.45026 46.30782 -45.82067 1.000 52.68923 ? 171 ALA B O   1 
ATOM   3554 C CB  . ALA B 1 170 ? -14.64150 46.65806 -48.74370 1.000 50.80563 ? 171 ALA B CB  1 
ATOM   3555 N N   . ASN B 1 171 ? -15.62411 45.71104 -45.73405 1.000 47.07981 ? 172 ASN B N   1 
ATOM   3556 C CA  . ASN B 1 171 ? -15.82241 46.11143 -44.34353 1.000 49.64060 ? 172 ASN B CA  1 
ATOM   3557 C C   . ASN B 1 171 ? -15.51757 44.99733 -43.34350 1.000 50.07932 ? 172 ASN B C   1 
ATOM   3558 O O   . ASN B 1 171 ? -15.92611 45.10016 -42.17799 1.000 47.09180 ? 172 ASN B O   1 
ATOM   3559 C CB  . ASN B 1 171 ? -17.25520 46.59423 -44.13924 1.000 48.19309 ? 172 ASN B CB  1 
ATOM   3560 C CG  . ASN B 1 171 ? -18.25594 45.49467 -44.35654 1.000 61.34566 ? 172 ASN B CG  1 
ATOM   3561 O OD1 . ASN B 1 171 ? -18.26511 44.87180 -45.40794 1.000 60.74131 ? 172 ASN B OD1 1 
ATOM   3562 N ND2 . ASN B 1 171 ? -19.11953 45.26551 -43.38780 1.000 65.13631 ? 172 ASN B ND2 1 
ATOM   3563 N N   . GLY B 1 172 ? -14.79551 43.95384 -43.75538 1.000 45.24499 ? 173 GLY B N   1 
ATOM   3564 C CA  . GLY B 1 172 ? -14.48064 42.85553 -42.86103 1.000 43.09081 ? 173 GLY B CA  1 
ATOM   3565 C C   . GLY B 1 172 ? -15.58671 41.83662 -42.69427 1.000 41.53729 ? 173 GLY B C   1 
ATOM   3566 O O   . GLY B 1 172 ? -15.37895 40.82303 -42.01222 1.000 35.27101 ? 173 GLY B O   1 
ATOM   3567 N N   . THR B 1 173 ? -16.74615 42.06876 -43.29762 1.000 35.29645 ? 174 THR B N   1 
ATOM   3568 C CA  . THR B 1 173 ? -17.85990 41.14897 -43.20955 1.000 35.86465 ? 174 THR B CA  1 
ATOM   3569 C C   . THR B 1 173 ? -17.70245 40.05334 -44.27217 1.000 30.33400 ? 174 THR B C   1 
ATOM   3570 O O   . THR B 1 173 ? -16.86833 40.14996 -45.17479 1.000 28.97238 ? 174 THR B O   1 
ATOM   3571 C CB  . THR B 1 173 ? -19.16906 41.93008 -43.36197 1.000 37.90628 ? 174 THR B CB  1 
ATOM   3572 O OG1 . THR B 1 173 ? -20.23269 41.20150 -42.75311 1.000 44.34642 ? 174 THR B OG1 1 
ATOM   3573 C CG2 . THR B 1 173 ? -19.50657 42.13696 -44.79411 1.000 36.51918 ? 174 THR B CG2 1 
ATOM   3574 N N   . HIS B 1 174 ? -18.50189 38.99650 -44.14865 1.000 28.55635 ? 175 HIS B N   1 
ATOM   3575 C CA  . HIS B 1 174 ? -18.31846 37.79703 -44.96171 1.000 28.37522 ? 175 HIS B CA  1 
ATOM   3576 C C   . HIS B 1 174 ? -19.61706 37.40932 -45.63977 1.000 25.68411 ? 175 HIS B C   1 
ATOM   3577 O O   . HIS B 1 174 ? -20.70364 37.63472 -45.10361 1.000 25.55983 ? 175 HIS B O   1 
ATOM   3578 C CB  . HIS B 1 174 ? -17.81730 36.62737 -44.09786 1.000 25.37035 ? 175 HIS B CB  1 
ATOM   3579 C CG  . HIS B 1 174 ? -16.56179 36.94730 -43.36467 1.000 25.96205 ? 175 HIS B CG  1 
ATOM   3580 N ND1 . HIS B 1 174 ? -16.53845 37.22035 -42.01297 1.000 29.49309 ? 175 HIS B ND1 1 
ATOM   3581 C CD2 . HIS B 1 174 ? -15.29007 37.09203 -43.80299 1.000 25.37753 ? 175 HIS B CD2 1 
ATOM   3582 C CE1 . HIS B 1 174 ? -15.30188 37.50197 -41.64559 1.000 27.29026 ? 175 HIS B CE1 1 
ATOM   3583 N NE2 . HIS B 1 174 ? -14.52431 37.43330 -42.71257 1.000 29.32948 ? 175 HIS B NE2 1 
ATOM   3584 N N   . THR B 1 175 ? -19.50393 36.76500 -46.80238 1.000 25.93937 ? 176 THR B N   1 
ATOM   3585 C CA  . THR B 1 175 ? -20.68344 36.17156 -47.40929 1.000 24.20265 ? 176 THR B CA  1 
ATOM   3586 C C   . THR B 1 175 ? -20.32996 34.82738 -48.03979 1.000 23.47504 ? 176 THR B C   1 
ATOM   3587 O O   . THR B 1 175 ? -19.16191 34.49045 -48.24044 1.000 23.24260 ? 176 THR B O   1 
ATOM   3588 C CB  . THR B 1 175 ? -21.31682 37.11213 -48.44580 1.000 29.02457 ? 176 THR B CB  1 
ATOM   3589 O OG1 . THR B 1 175 ? -22.70788 36.76685 -48.62433 1.000 30.07922 ? 176 THR B OG1 1 
ATOM   3590 C CG2 . THR B 1 175 ? -20.54382 37.04606 -49.76872 1.000 27.50999 ? 176 THR B CG2 1 
ATOM   3591 N N   . GLY B 1 176 ? -21.36742 34.05631 -48.32031 1.000 24.41834 ? 177 GLY B N   1 
ATOM   3592 C CA  . GLY B 1 176 ? -21.21017 32.78198 -48.97476 1.000 24.28508 ? 177 GLY B CA  1 
ATOM   3593 C C   . GLY B 1 176 ? -22.50438 32.37647 -49.63714 1.000 26.26172 ? 177 GLY B C   1 
ATOM   3594 O O   . GLY B 1 176 ? -23.42305 33.18471 -49.79644 1.000 27.22975 ? 177 GLY B O   1 
ATOM   3595 N N   . SER B 1 177 ? -22.56495 31.10407 -50.01960 1.000 23.92214 ? 178 SER B N   1 
ATOM   3596 C CA  . SER B 1 177 ? -23.67338 30.55486 -50.78325 1.000 24.16286 ? 178 SER B CA  1 
ATOM   3597 C C   . SER B 1 177 ? -24.51298 29.62823 -49.92284 1.000 25.79101 ? 178 SER B C   1 
ATOM   3598 O O   . SER B 1 177 ? -24.01406 29.00049 -48.97875 1.000 25.69994 ? 178 SER B O   1 
ATOM   3599 C CB  . SER B 1 177 ? -23.17287 29.76267 -51.99687 1.000 25.77270 ? 178 SER B CB  1 
ATOM   3600 O OG  . SER B 1 177 ? -22.16271 30.47853 -52.68696 1.000 33.40259 ? 178 SER B OG  1 
ATOM   3601 N N   . ALA B 1 178 ? -25.79691 29.54984 -50.26717 1.000 24.93613 ? 179 ALA B N   1 
ATOM   3602 C CA  . ALA B 1 178 ? -26.62378 28.41349 -49.90073 1.000 26.23559 ? 179 ALA B CA  1 
ATOM   3603 C C   . ALA B 1 178 ? -26.30274 27.23656 -50.82617 1.000 24.32921 ? 179 ALA B C   1 
ATOM   3604 O O   . ALA B 1 178 ? -25.72251 27.40372 -51.90101 1.000 26.27214 ? 179 ALA B O   1 
ATOM   3605 C CB  . ALA B 1 178 ? -28.10913 28.76048 -49.99644 1.000 28.73065 ? 179 ALA B CB  1 
ATOM   3606 N N   . PHE B 1 179 ? -26.66620 26.03781 -50.39416 1.000 28.35488 ? 180 PHE B N   1 
ATOM   3607 C CA  . PHE B 1 179 ? -26.28949 24.86322 -51.17888 1.000 30.02660 ? 180 PHE B CA  1 
ATOM   3608 C C   . PHE B 1 179 ? -27.17448 24.65178 -52.40130 1.000 33.70632 ? 180 PHE B C   1 
ATOM   3609 O O   . PHE B 1 179 ? -26.93069 23.71591 -53.17133 1.000 32.90017 ? 180 PHE B O   1 
ATOM   3610 C CB  . PHE B 1 179 ? -26.26155 23.61962 -50.28211 1.000 29.44655 ? 180 PHE B CB  1 
ATOM   3611 C CG  . PHE B 1 179 ? -25.02525 23.55422 -49.43298 1.000 29.31324 ? 180 PHE B CG  1 
ATOM   3612 C CD1 . PHE B 1 179 ? -24.94655 24.27953 -48.25934 1.000 26.98604 ? 180 PHE B CD1 1 
ATOM   3613 C CD2 . PHE B 1 179 ? -23.91415 22.83793 -49.84998 1.000 26.83896 ? 180 PHE B CD2 1 
ATOM   3614 C CE1 . PHE B 1 179 ? -23.79042 24.25654 -47.48833 1.000 28.77400 ? 180 PHE B CE1 1 
ATOM   3615 C CE2 . PHE B 1 179 ? -22.75506 22.80446 -49.08559 1.000 27.08451 ? 180 PHE B CE2 1 
ATOM   3616 C CZ  . PHE B 1 179 ? -22.68724 23.52240 -47.90831 1.000 25.32096 ? 180 PHE B CZ  1 
ATOM   3617 N N   . ASP B 1 180 ? -28.17355 25.50016 -52.62645 1.000 32.70462 ? 181 ASP B N   1 
ATOM   3618 C CA  . ASP B 1 180 ? -28.74509 25.54033 -53.96422 1.000 34.62428 ? 181 ASP B CA  1 
ATOM   3619 C C   . ASP B 1 180 ? -27.85422 26.30015 -54.93184 1.000 30.77555 ? 181 ASP B C   1 
ATOM   3620 O O   . ASP B 1 180 ? -28.15863 26.34924 -56.12544 1.000 35.96073 ? 181 ASP B O   1 
ATOM   3621 C CB  . ASP B 1 180 ? -30.15906 26.14273 -53.93603 1.000 36.23892 ? 181 ASP B CB  1 
ATOM   3622 C CG  . ASP B 1 180 ? -30.19100 27.58102 -53.43499 1.000 36.67911 ? 181 ASP B CG  1 
ATOM   3623 O OD1 . ASP B 1 180 ? -29.12332 28.22987 -53.31302 1.000 32.44191 ? 181 ASP B OD1 1 
ATOM   3624 O OD2 . ASP B 1 180 ? -31.30912 28.06673 -53.17020 1.000 40.73949 ? 181 ASP B OD2 1 
ATOM   3625 N N   . GLY B 1 181 ? -26.76239 26.89481 -54.44655 1.000 27.52191 ? 182 GLY B N   1 
ATOM   3626 C CA  . GLY B 1 181 ? -25.82137 27.59868 -55.28283 1.000 27.22882 ? 182 GLY B CA  1 
ATOM   3627 C C   . GLY B 1 181 ? -25.97720 29.10998 -55.31843 1.000 26.36110 ? 182 GLY B C   1 
ATOM   3628 O O   . GLY B 1 181 ? -25.12856 29.77963 -55.90624 1.000 28.21886 ? 182 GLY B O   1 
ATOM   3629 N N   . THR B 1 182 ? -27.01613 29.66995 -54.71079 1.000 28.51496 ? 183 THR B N   1 
ATOM   3630 C CA  . THR B 1 182 ? -27.22562 31.11466 -54.75634 1.000 29.99758 ? 183 THR B CA  1 
ATOM   3631 C C   . THR B 1 182 ? -26.43829 31.81294 -53.64807 1.000 30.64051 ? 183 THR B C   1 
ATOM   3632 O O   . THR B 1 182 ? -26.51106 31.41839 -52.47981 1.000 29.73521 ? 183 THR B O   1 
ATOM   3633 C CB  . THR B 1 182 ? -28.70990 31.44851 -54.62553 1.000 31.29502 ? 183 THR B CB  1 
ATOM   3634 O OG1 . THR B 1 182 ? -29.18288 31.01868 -53.34479 1.000 36.80870 ? 183 THR B OG1 1 
ATOM   3635 C CG2 . THR B 1 182 ? -29.50521 30.73946 -55.69235 1.000 34.54860 ? 183 THR B CG2 1 
ATOM   3636 N N   . MET B 1 183 ? -25.69311 32.84905 -54.01748 1.000 27.12744 ? 184 MET B N   1 
ATOM   3637 C CA  . MET B 1 183 ? -24.97470 33.64337 -53.03154 1.000 28.83773 ? 184 MET B CA  1 
ATOM   3638 C C   . MET B 1 183 ? -25.95446 34.45169 -52.19276 1.000 30.01675 ? 184 MET B C   1 
ATOM   3639 O O   . MET B 1 183 ? -26.83404 35.13101 -52.73152 1.000 30.33840 ? 184 MET B O   1 
ATOM   3640 C CB  . MET B 1 183 ? -23.99018 34.58037 -53.72293 1.000 31.35974 ? 184 MET B CB  1 
ATOM   3641 C CG  . MET B 1 183 ? -23.09609 35.35944 -52.76082 1.000 32.38621 ? 184 MET B CG  1 
ATOM   3642 S SD  . MET B 1 183 ? -21.59235 34.43137 -52.34848 1.000 36.28005 ? 184 MET B SD  1 
ATOM   3643 C CE  . MET B 1 183 ? -20.68643 34.52107 -53.89248 1.000 33.32497 ? 184 MET B CE  1 
ATOM   3644 N N   . TYR B 1 184 ? -25.80721 34.38384 -50.87093 1.000 27.57028 ? 185 TYR B N   1 
ATOM   3645 C CA  . TYR B 1 184 ? -26.60834 35.24402 -50.01192 1.000 26.72125 ? 185 TYR B CA  1 
ATOM   3646 C C   . TYR B 1 184 ? -26.36628 36.69936 -50.39496 1.000 24.12964 ? 185 TYR B C   1 
ATOM   3647 O O   . TYR B 1 184 ? -25.22333 37.11941 -50.58163 1.000 27.72948 ? 185 TYR B O   1 
ATOM   3648 C CB  . TYR B 1 184 ? -26.25983 35.00323 -48.54329 1.000 26.77020 ? 185 TYR B CB  1 
ATOM   3649 C CG  . TYR B 1 184 ? -26.84501 33.72457 -48.00169 1.000 21.15230 ? 185 TYR B CG  1 
ATOM   3650 C CD1 . TYR B 1 184 ? -28.18473 33.64859 -47.64159 1.000 23.83593 ? 185 TYR B CD1 1 
ATOM   3651 C CD2 . TYR B 1 184 ? -26.07034 32.57299 -47.90432 1.000 22.88315 ? 185 TYR B CD2 1 
ATOM   3652 C CE1 . TYR B 1 184 ? -28.73076 32.47576 -47.15373 1.000 28.60839 ? 185 TYR B CE1 1 
ATOM   3653 C CE2 . TYR B 1 184 ? -26.60838 31.39256 -47.41753 1.000 21.95627 ? 185 TYR B CE2 1 
ATOM   3654 C CZ  . TYR B 1 184 ? -27.92943 31.34781 -47.04123 1.000 24.17855 ? 185 TYR B CZ  1 
ATOM   3655 O OH  . TYR B 1 184 ? -28.46726 30.18672 -46.56267 1.000 26.86470 ? 185 TYR B OH  1 
ATOM   3656 N N   . GLY B 1 185 ? -27.44699 37.45840 -50.56081 1.000 29.98602 ? 186 GLY B N   1 
ATOM   3657 C CA  . GLY B 1 185 ? -27.30658 38.85766 -50.93422 1.000 30.13592 ? 186 GLY B CA  1 
ATOM   3658 C C   . GLY B 1 185 ? -26.81370 39.11514 -52.34393 1.000 32.78014 ? 186 GLY B C   1 
ATOM   3659 O O   . GLY B 1 185 ? -26.41428 40.24153 -52.64188 1.000 34.66578 ? 186 GLY B O   1 
ATOM   3660 N N   . ALA B 1 186 ? -26.81206 38.09964 -53.20679 1.000 32.78713 ? 187 ALA B N   1 
ATOM   3661 C CA  . ALA B 1 186 ? -26.44473 38.19362 -54.62079 1.000 31.67144 ? 187 ALA B CA  1 
ATOM   3662 C C   . ALA B 1 186 ? -25.05318 38.75842 -54.84965 1.000 35.36308 ? 187 ALA B C   1 
ATOM   3663 O O   . ALA B 1 186 ? -24.77098 39.26090 -55.93885 1.000 37.62227 ? 187 ALA B O   1 
ATOM   3664 C CB  . ALA B 1 186 ? -27.46422 39.02066 -55.41432 1.000 33.59064 ? 187 ALA B CB  1 
ATOM   3665 N N   . PHE B 1 187 ? -24.15292 38.70017 -53.86986 1.000 31.56766 ? 188 PHE B N   1 
ATOM   3666 C CA  . PHE B 1 187 ? -22.80932 39.20761 -54.11237 1.000 32.99397 ? 188 PHE B CA  1 
ATOM   3667 C C   . PHE B 1 187 ? -22.11839 38.36475 -55.18097 1.000 34.25958 ? 188 PHE B C   1 
ATOM   3668 O O   . PHE B 1 187 ? -22.40542 37.17677 -55.34588 1.000 32.11861 ? 188 PHE B O   1 
ATOM   3669 C CB  . PHE B 1 187 ? -21.98423 39.21835 -52.82360 1.000 33.84678 ? 188 PHE B CB  1 
ATOM   3670 C CG  . PHE B 1 187 ? -22.52840 40.13512 -51.76283 1.000 34.00732 ? 188 PHE B CG  1 
ATOM   3671 C CD1 . PHE B 1 187 ? -22.23850 41.49019 -51.78443 1.000 33.04166 ? 188 PHE B CD1 1 
ATOM   3672 C CD2 . PHE B 1 187 ? -23.32583 39.63806 -50.73772 1.000 33.27525 ? 188 PHE B CD2 1 
ATOM   3673 C CE1 . PHE B 1 187 ? -22.73761 42.33309 -50.80639 1.000 39.17077 ? 188 PHE B CE1 1 
ATOM   3674 C CE2 . PHE B 1 187 ? -23.82288 40.47814 -49.75631 1.000 32.12060 ? 188 PHE B CE2 1 
ATOM   3675 C CZ  . PHE B 1 187 ? -23.52957 41.82954 -49.79177 1.000 34.60555 ? 188 PHE B CZ  1 
ATOM   3676 N N   . MET B 1 188 ? -21.21960 38.99300 -55.93009 1.000 32.69877 ? 189 MET B N   1 
ATOM   3677 C CA  . MET B 1 188 ? -20.58970 38.32968 -57.06448 1.000 36.39091 ? 189 MET B CA  1 
ATOM   3678 C C   . MET B 1 188 ? -19.22438 37.79387 -56.65889 1.000 37.50268 ? 189 MET B C   1 
ATOM   3679 O O   . MET B 1 188 ? -18.45954 38.47445 -55.96803 1.000 36.07474 ? 189 MET B O   1 
ATOM   3680 C CB  . MET B 1 188 ? -20.46760 39.28186 -58.25702 1.000 36.09910 ? 189 MET B CB  1 
ATOM   3681 C CG  . MET B 1 188 ? -21.80728 39.82997 -58.72683 1.000 41.25586 ? 189 MET B CG  1 
ATOM   3682 S SD  . MET B 1 188 ? -21.71442 40.95092 -60.15292 1.000 48.70881 ? 189 MET B SD  1 
ATOM   3683 C CE  . MET B 1 188 ? -20.32024 41.98168 -59.67289 1.000 44.52397 ? 189 MET B CE  1 
ATOM   3684 N N   . ASP B 1 189 ? -18.92630 36.55795 -57.07379 1.000 36.73656 ? 190 ASP B N   1 
ATOM   3685 C CA  . ASP B 1 189 ? -17.64359 35.94194 -56.72870 1.000 38.54429 ? 190 ASP B CA  1 
ATOM   3686 C C   . ASP B 1 189 ? -16.58032 36.40708 -57.72701 1.000 41.29445 ? 190 ASP B C   1 
ATOM   3687 O O   . ASP B 1 189 ? -16.05977 35.64388 -58.54580 1.000 38.95491 ? 190 ASP B O   1 
ATOM   3688 C CB  . ASP B 1 189 ? -17.74492 34.41770 -56.66673 1.000 36.57268 ? 190 ASP B CB  1 
ATOM   3689 C CG  . ASP B 1 189 ? -18.57229 33.80433 -57.80454 1.000 38.81297 ? 190 ASP B CG  1 
ATOM   3690 O OD1 . ASP B 1 189 ? -19.17601 34.55684 -58.60644 1.000 34.43122 ? 190 ASP B OD1 1 
ATOM   3691 O OD2 . ASP B 1 189 ? -18.61534 32.54404 -57.88421 1.000 30.44142 ? 190 ASP B OD2 1 
ATOM   3692 N N   . LYS B 1 190 ? -16.25519 37.69973 -57.62522 1.000 41.77021 ? 191 LYS B N   1 
ATOM   3693 C CA  . LYS B 1 190 ? -15.26072 38.36883 -58.45702 1.000 49.32733 ? 191 LYS B CA  1 
ATOM   3694 C C   . LYS B 1 190 ? -14.48812 39.37920 -57.61777 1.000 49.49497 ? 191 LYS B C   1 
ATOM   3695 O O   . LYS B 1 190 ? -15.01944 39.93618 -56.65420 1.000 44.32326 ? 191 LYS B O   1 
ATOM   3696 C CB  . LYS B 1 190 ? -15.90012 39.11323 -59.64175 1.000 47.79788 ? 191 LYS B CB  1 
ATOM   3697 C CG  . LYS B 1 190 ? -16.81643 38.27052 -60.50905 1.000 52.73213 ? 191 LYS B CG  1 
ATOM   3698 C CD  . LYS B 1 190 ? -17.15029 38.96130 -61.82212 1.000 53.44263 ? 191 LYS B CD  1 
ATOM   3699 C CE  . LYS B 1 190 ? -18.33497 39.89742 -61.68312 1.000 57.33374 ? 191 LYS B CE  1 
ATOM   3700 N NZ  . LYS B 1 190 ? -19.04059 40.08310 -62.98506 1.000 53.82445 ? 191 LYS B NZ  1 
ATOM   3701 N N   . GLN B 1 191 ? -13.22757 39.62182 -58.00385 1.000 52.03973 ? 192 GLN B N   1 
ATOM   3702 C CA  . GLN B 1 191 ? -12.42757 40.69541 -57.42075 1.000 49.95959 ? 192 GLN B CA  1 
ATOM   3703 C C   . GLN B 1 191 ? -12.92310 42.03323 -57.94632 1.000 59.13967 ? 192 GLN B C   1 
ATOM   3704 O O   . GLN B 1 191 ? -12.23899 42.69968 -58.72971 1.000 56.66141 ? 192 GLN B O   1 
ATOM   3705 C CB  . GLN B 1 191 ? -10.94029 40.52823 -57.73299 1.000 52.37771 ? 192 GLN B CB  1 
ATOM   3706 N N   . VAL B 1 192 ? -14.13206 42.40328 -57.53688 1.000 59.54840 ? 193 VAL B N   1 
ATOM   3707 C CA  . VAL B 1 192 ? -14.75505 43.67947 -57.85354 1.000 61.80576 ? 193 VAL B CA  1 
ATOM   3708 C C   . VAL B 1 192 ? -15.19002 44.30139 -56.53705 1.000 62.49941 ? 193 VAL B C   1 
ATOM   3709 O O   . VAL B 1 192 ? -15.76773 43.61263 -55.68845 1.000 63.07269 ? 193 VAL B O   1 
ATOM   3710 C CB  . VAL B 1 192 ? -15.97050 43.50327 -58.78560 1.000 57.39163 ? 193 VAL B CB  1 
ATOM   3711 C CG1 . VAL B 1 192 ? -16.63878 44.84200 -59.05933 1.000 62.59798 ? 193 VAL B CG1 1 
ATOM   3712 C CG2 . VAL B 1 192 ? -15.56483 42.81336 -60.07518 1.000 60.81422 ? 193 VAL B CG2 1 
ATOM   3713 N N   . HIS B 1 193 ? -14.90422 45.58697 -56.35072 1.000 67.71963 ? 194 HIS B N   1 
ATOM   3714 C CA  . HIS B 1 193 ? -15.50365 46.27851 -55.21978 1.000 66.36888 ? 194 HIS B CA  1 
ATOM   3715 C C   . HIS B 1 193 ? -17.01298 46.31730 -55.41922 1.000 64.26640 ? 194 HIS B C   1 
ATOM   3716 O O   . HIS B 1 193 ? -17.50324 46.71040 -56.48296 1.000 67.19209 ? 194 HIS B O   1 
ATOM   3717 C CB  . HIS B 1 193 ? -14.93420 47.69208 -55.06746 1.000 71.47011 ? 194 HIS B CB  1 
ATOM   3718 C CG  . HIS B 1 193 ? -15.18855 48.30398 -53.71958 1.000 74.70447 ? 194 HIS B CG  1 
ATOM   3719 N ND1 . HIS B 1 193 ? -15.97083 49.42774 -53.54466 1.000 74.54642 ? 194 HIS B ND1 1 
ATOM   3720 C CD2 . HIS B 1 193 ? -14.76896 47.94332 -52.48165 1.000 74.03944 ? 194 HIS B CD2 1 
ATOM   3721 C CE1 . HIS B 1 193 ? -16.01929 49.73426 -52.25949 1.000 76.39001 ? 194 HIS B CE1 1 
ATOM   3722 N NE2 . HIS B 1 193 ? -15.29970 48.84842 -51.59243 1.000 77.12483 ? 194 HIS B NE2 1 
ATOM   3723 N N   . GLN B 1 194 ? -17.74985 45.85719 -54.41269 1.000 62.20624 ? 195 GLN B N   1 
ATOM   3724 C CA  . GLN B 1 194 ? -19.20127 45.83468 -54.48117 1.000 57.48193 ? 195 GLN B CA  1 
ATOM   3725 C C   . GLN B 1 194 ? -19.75855 46.36636 -53.17203 1.000 59.04491 ? 195 GLN B C   1 
ATOM   3726 O O   . GLN B 1 194 ? -19.08487 46.36429 -52.13783 1.000 58.25418 ? 195 GLN B O   1 
ATOM   3727 C CB  . GLN B 1 194 ? -19.74033 44.42892 -54.76875 1.000 56.04900 ? 195 GLN B CB  1 
ATOM   3728 C CG  . GLN B 1 194 ? -18.95322 43.30159 -54.11517 1.000 49.22266 ? 195 GLN B CG  1 
ATOM   3729 C CD  . GLN B 1 194 ? -19.17047 41.97311 -54.82548 1.000 41.19847 ? 195 GLN B CD  1 
ATOM   3730 O OE1 . GLN B 1 194 ? -20.29833 41.62153 -55.16876 1.000 37.65969 ? 195 GLN B OE1 1 
ATOM   3731 N NE2 . GLN B 1 194 ? -18.08578 41.23809 -55.06287 1.000 43.20231 ? 195 GLN B NE2 1 
ATOM   3732 N N   . VAL B 1 195 ? -21.00671 46.81468 -53.22861 1.000 57.18702 ? 196 VAL B N   1 
ATOM   3733 C CA  . VAL B 1 195 ? -21.62387 47.56319 -52.13976 1.000 59.23321 ? 196 VAL B CA  1 
ATOM   3734 C C   . VAL B 1 195 ? -22.60779 46.66483 -51.40044 1.000 48.24665 ? 196 VAL B C   1 
ATOM   3735 O O   . VAL B 1 195 ? -23.56562 46.14610 -51.99177 1.000 46.41473 ? 196 VAL B O   1 
ATOM   3736 C CB  . VAL B 1 195 ? -22.32029 48.82937 -52.66297 1.000 58.39604 ? 196 VAL B CB  1 
ATOM   3737 C CG1 . VAL B 1 195 ? -23.36302 49.32716 -51.65894 1.000 57.80122 ? 196 VAL B CG1 1 
ATOM   3738 C CG2 . VAL B 1 195 ? -21.28984 49.90868 -52.96500 1.000 56.77244 ? 196 VAL B CG2 1 
ATOM   3739 N N   . GLN B 1 196 ? -22.37766 46.48826 -50.10302 1.000 51.51369 ? 197 GLN B N   1 
ATOM   3740 C CA  . GLN B 1 196 ? -23.36509 45.83920 -49.25347 1.000 48.32383 ? 197 GLN B CA  1 
ATOM   3741 C C   . GLN B 1 196 ? -24.40884 46.85937 -48.82093 1.000 43.25660 ? 197 GLN B C   1 
ATOM   3742 O O   . GLN B 1 196 ? -24.10187 48.03496 -48.59864 1.000 42.57356 ? 197 GLN B O   1 
ATOM   3743 C CB  . GLN B 1 196 ? -22.70805 45.21523 -48.02312 1.000 45.91151 ? 197 GLN B CB  1 
ATOM   3744 C CG  . GLN B 1 196 ? -22.38501 46.23308 -46.95309 1.000 50.87089 ? 197 GLN B CG  1 
ATOM   3745 C CD  . GLN B 1 196 ? -21.10580 45.93166 -46.23883 1.000 58.27968 ? 197 GLN B CD  1 
ATOM   3746 O OE1 . GLN B 1 196 ? -21.11913 45.53758 -45.06676 1.000 67.72938 ? 197 GLN B OE1 1 
ATOM   3747 N NE2 . GLN B 1 196 ? -19.97950 46.09229 -46.93862 1.000 57.03400 ? 197 GLN B NE2 1 
ATOM   3748 N N   . LEU B 1 197 ? -25.65020 46.41062 -48.72022 1.000 39.68827 ? 198 LEU B N   1 
ATOM   3749 C CA  . LEU B 1 197 ? -26.69306 47.28732 -48.23300 1.000 36.97230 ? 198 LEU B CA  1 
ATOM   3750 C C   . LEU B 1 197 ? -26.44710 47.60718 -46.75837 1.000 39.44860 ? 198 LEU B C   1 
ATOM   3751 O O   . LEU B 1 197 ? -25.65288 46.95293 -46.07246 1.000 33.51713 ? 198 LEU B O   1 
ATOM   3752 C CB  . LEU B 1 197 ? -28.06946 46.64713 -48.42385 1.000 38.05616 ? 198 LEU B CB  1 
ATOM   3753 C CG  . LEU B 1 197 ? -28.69402 46.49194 -49.82429 1.000 42.45438 ? 198 LEU B CG  1 
ATOM   3754 C CD1 . LEU B 1 197 ? -27.82727 45.70758 -50.79736 1.000 38.37845 ? 198 LEU B CD1 1 
ATOM   3755 C CD2 . LEU B 1 197 ? -30.04982 45.81703 -49.70088 1.000 41.10540 ? 198 LEU B CD2 1 
ATOM   3756 N N   . THR B 1 198 ? -27.12556 48.64690 -46.28034 1.000 37.32853 ? 199 THR B N   1 
ATOM   3757 C CA  . THR B 1 198 ? -27.01817 49.03420 -44.88199 1.000 38.36744 ? 199 THR B CA  1 
ATOM   3758 C C   . THR B 1 198 ? -27.65699 47.97306 -43.99114 1.000 39.17543 ? 199 THR B C   1 
ATOM   3759 O O   . THR B 1 198 ? -28.74965 47.47416 -44.27715 1.000 36.89633 ? 199 THR B O   1 
ATOM   3760 C CB  . THR B 1 198 ? -27.68294 50.39921 -44.67058 1.000 39.95666 ? 199 THR B CB  1 
ATOM   3761 O OG1 . THR B 1 198 ? -26.76796 51.43085 -45.06549 1.000 48.58634 ? 199 THR B OG1 1 
ATOM   3762 C CG2 . THR B 1 198 ? -28.07520 50.60756 -43.21584 1.000 40.78750 ? 199 THR B CG2 1 
ATOM   3763 N N   . ASP B 1 199 ? -26.96101 47.61184 -42.91497 1.000 32.54068 ? 200 ASP B N   1 
ATOM   3764 C CA  . ASP B 1 199 ? -27.50556 46.63465 -41.98601 1.000 34.28889 ? 200 ASP B CA  1 
ATOM   3765 C C   . ASP B 1 199 ? -28.73400 47.19153 -41.25675 1.000 35.37859 ? 200 ASP B C   1 
ATOM   3766 O O   . ASP B 1 199 ? -29.05511 48.38463 -41.31877 1.000 33.01817 ? 200 ASP B O   1 
ATOM   3767 C CB  . ASP B 1 199 ? -26.44642 46.20763 -40.97177 1.000 31.59910 ? 200 ASP B CB  1 
ATOM   3768 C CG  . ASP B 1 199 ? -26.67076 44.79057 -40.45404 1.000 32.59029 ? 200 ASP B CG  1 
ATOM   3769 O OD1 . ASP B 1 199 ? -27.59355 44.11113 -40.94477 1.000 37.54271 ? 200 ASP B OD1 1 
ATOM   3770 O OD2 . ASP B 1 199 ? -25.90602 44.35140 -39.58334 1.000 37.25362 ? 200 ASP B OD2 1 
ATOM   3771 N N   . LYS B 1 200 ? -29.42202 46.29586 -40.55158 1.000 30.22911 ? 201 LYS B N   1 
ATOM   3772 C CA  . LYS B 1 200 ? -30.61823 46.62082 -39.79088 1.000 32.35227 ? 201 LYS B CA  1 
ATOM   3773 C C   . LYS B 1 200 ? -30.62556 45.80387 -38.50878 1.000 31.98333 ? 201 LYS B C   1 
ATOM   3774 O O   . LYS B 1 200 ? -29.95822 44.77014 -38.40908 1.000 30.22108 ? 201 LYS B O   1 
ATOM   3775 C CB  . LYS B 1 200 ? -31.89548 46.32652 -40.58423 1.000 29.44329 ? 201 LYS B CB  1 
ATOM   3776 C CG  . LYS B 1 200 ? -32.09016 47.22975 -41.79260 1.000 35.04334 ? 201 LYS B CG  1 
ATOM   3777 C CD  . LYS B 1 200 ? -33.06228 46.62993 -42.78879 1.000 37.55536 ? 201 LYS B CD  1 
ATOM   3778 C CE  . LYS B 1 200 ? -33.24985 47.56446 -43.99755 1.000 39.86587 ? 201 LYS B CE  1 
ATOM   3779 N NZ  . LYS B 1 200 ? -34.31847 47.08246 -44.91645 1.000 49.76541 ? 201 LYS B NZ  1 
ATOM   3780 N N   . TYR B 1 201 ? -31.39568 46.26916 -37.52558 1.000 25.79811 ? 202 TYR B N   1 
ATOM   3781 C CA  . TYR B 1 201 ? -31.67088 45.43149 -36.36401 1.000 27.76702 ? 202 TYR B CA  1 
ATOM   3782 C C   . TYR B 1 201 ? -32.63087 44.32552 -36.75333 1.000 28.61016 ? 202 TYR B C   1 
ATOM   3783 O O   . TYR B 1 201 ? -33.62514 44.57143 -37.43967 1.000 26.38731 ? 202 TYR B O   1 
ATOM   3784 C CB  . TYR B 1 201 ? -32.28557 46.24370 -35.23066 1.000 27.91396 ? 202 TYR B CB  1 
ATOM   3785 C CG  . TYR B 1 201 ? -31.32515 47.17956 -34.54982 1.000 29.42696 ? 202 TYR B CG  1 
ATOM   3786 C CD1 . TYR B 1 201 ? -30.35466 46.69648 -33.67751 1.000 35.12684 ? 202 TYR B CD1 1 
ATOM   3787 C CD2 . TYR B 1 201 ? -31.39006 48.54710 -34.77267 1.000 33.97498 ? 202 TYR B CD2 1 
ATOM   3788 C CE1 . TYR B 1 201 ? -29.47206 47.55494 -33.05006 1.000 34.96884 ? 202 TYR B CE1 1 
ATOM   3789 C CE2 . TYR B 1 201 ? -30.51651 49.41015 -34.14961 1.000 38.53955 ? 202 TYR B CE2 1 
ATOM   3790 C CZ  . TYR B 1 201 ? -29.56329 48.90403 -33.28463 1.000 36.15515 ? 202 TYR B CZ  1 
ATOM   3791 O OH  . TYR B 1 201 ? -28.69734 49.76590 -32.66307 1.000 45.51251 ? 202 TYR B OH  1 
ATOM   3792 N N   . CYS B 1 202 ? -32.32985 43.10102 -36.31932 1.000 26.61525 ? 203 CYS B N   1 
ATOM   3793 C CA  . CYS B 1 202 ? -33.24625 41.97877 -36.49006 1.000 25.88265 ? 203 CYS B CA  1 
ATOM   3794 C C   . CYS B 1 202 ? -34.31484 42.07085 -35.41215 1.000 24.76537 ? 203 CYS B C   1 
ATOM   3795 O O   . CYS B 1 202 ? -34.06304 41.73839 -34.25371 1.000 23.82609 ? 203 CYS B O   1 
ATOM   3796 C CB  . CYS B 1 202 ? -32.49737 40.65174 -36.40198 1.000 27.93554 ? 203 CYS B CB  1 
ATOM   3797 S SG  . CYS B 1 202 ? -31.13746 40.55677 -37.56722 1.000 33.08427 ? 203 CYS B SG  1 
ATOM   3798 N N   . SER B 1 203 ? -35.51903 42.49395 -35.80510 1.000 28.97377 ? 204 SER B N   1 
ATOM   3799 C CA  . SER B 1 203 ? -36.56011 42.85601 -34.84381 1.000 24.36824 ? 204 SER B CA  1 
ATOM   3800 C C   . SER B 1 203 ? -36.98502 41.68534 -33.97164 1.000 24.50115 ? 204 SER B C   1 
ATOM   3801 O O   . SER B 1 203 ? -37.22617 41.85783 -32.77153 1.000 23.68220 ? 204 SER B O   1 
ATOM   3802 C CB  . SER B 1 203 ? -37.77792 43.41519 -35.58897 1.000 25.42748 ? 204 SER B CB  1 
ATOM   3803 O OG  . SER B 1 203 ? -37.39057 44.55351 -36.33419 1.000 29.57922 ? 204 SER B OG  1 
ATOM   3804 N N   . VAL B 1 204 ? -37.13752 40.49521 -34.55525 1.000 24.32884 ? 205 VAL B N   1 
ATOM   3805 C CA  . VAL B 1 204 ? -37.61843 39.37344 -33.74679 1.000 25.85420 ? 205 VAL B CA  1 
ATOM   3806 C C   . VAL B 1 204 ? -36.57450 38.96664 -32.70279 1.000 23.17035 ? 205 VAL B C   1 
ATOM   3807 O O   . VAL B 1 204 ? -36.93020 38.52862 -31.60192 1.000 21.79625 ? 205 VAL B O   1 
ATOM   3808 C CB  . VAL B 1 204 ? -38.01406 38.19112 -34.65631 1.000 28.25081 ? 205 VAL B CB  1 
ATOM   3809 C CG1 . VAL B 1 204 ? -36.81520 37.68318 -35.43946 1.000 30.68871 ? 205 VAL B CG1 1 
ATOM   3810 C CG2 . VAL B 1 204 ? -38.61898 37.08008 -33.83441 1.000 25.71886 ? 205 VAL B CG2 1 
ATOM   3811 N N   . ASN B 1 205 ? -35.28345 39.14662 -33.00920 1.000 21.86551 ? 206 ASN B N   1 
ATOM   3812 C CA  . ASN B 1 205 ? -34.22848 38.85704 -32.03457 1.000 25.97449 ? 206 ASN B CA  1 
ATOM   3813 C C   . ASN B 1 205 ? -34.14635 39.92436 -30.93865 1.000 25.59491 ? 206 ASN B C   1 
ATOM   3814 O O   . ASN B 1 205 ? -33.81083 39.60497 -29.79151 1.000 23.65615 ? 206 ASN B O   1 
ATOM   3815 C CB  . ASN B 1 205 ? -32.87218 38.74208 -32.72998 1.000 24.52992 ? 206 ASN B CB  1 
ATOM   3816 C CG  . ASN B 1 205 ? -32.75682 37.50828 -33.62354 1.000 21.82541 ? 206 ASN B CG  1 
ATOM   3817 O OD1 . ASN B 1 205 ? -33.61319 36.63076 -33.62505 1.000 24.71262 ? 206 ASN B OD1 1 
ATOM   3818 N ND2 . ASN B 1 205 ? -31.67350 37.44640 -34.37912 1.000 24.51336 ? 206 ASN B ND2 1 
ATOM   3819 N N   . VAL B 1 206 ? -34.41771 41.19318 -31.26523 1.000 22.80899 ? 207 VAL B N   1 
ATOM   3820 C CA  . VAL B 1 206 ? -34.49394 42.20262 -30.20574 1.000 22.77192 ? 207 VAL B CA  1 
ATOM   3821 C C   . VAL B 1 206 ? -35.64387 41.87350 -29.25572 1.000 22.32398 ? 207 VAL B C   1 
ATOM   3822 O O   . VAL B 1 206 ? -35.50127 41.96385 -28.02723 1.000 25.70873 ? 207 VAL B O   1 
ATOM   3823 C CB  . VAL B 1 206 ? -34.61418 43.61869 -30.80371 1.000 22.58398 ? 207 VAL B CB  1 
ATOM   3824 C CG1 . VAL B 1 206 ? -34.77424 44.66705 -29.69087 1.000 25.03326 ? 207 VAL B CG1 1 
ATOM   3825 C CG2 . VAL B 1 206 ? -33.38148 43.94785 -31.62969 1.000 23.02444 ? 207 VAL B CG2 1 
ATOM   3826 N N   . VAL B 1 207 ? -36.77767 41.42840 -29.80397 1.000 24.21922 ? 208 VAL B N   1 
ATOM   3827 C CA  . VAL B 1 207 ? -37.90121 40.99178 -28.97390 1.000 21.62301 ? 208 VAL B CA  1 
ATOM   3828 C C   . VAL B 1 207 ? -37.47424 39.84409 -28.06554 1.000 25.31422 ? 208 VAL B C   1 
ATOM   3829 O O   . VAL B 1 207 ? -37.77604 39.82908 -26.86392 1.000 24.44529 ? 208 VAL B O   1 
ATOM   3830 C CB  . VAL B 1 207 ? -39.10227 40.59008 -29.85400 1.000 23.51185 ? 208 VAL B CB  1 
ATOM   3831 C CG1 . VAL B 1 207 ? -40.13054 39.80466 -29.02669 1.000 22.97996 ? 208 VAL B CG1 1 
ATOM   3832 C CG2 . VAL B 1 207 ? -39.75136 41.84287 -30.48087 1.000 25.41727 ? 208 VAL B CG2 1 
ATOM   3833 N N   . ALA B 1 208 ? -36.74364 38.87575 -28.62464 1.000 21.92442 ? 209 ALA B N   1 
ATOM   3834 C CA  . ALA B 1 208 ? -36.27188 37.74588 -27.82757 1.000 23.58198 ? 209 ALA B CA  1 
ATOM   3835 C C   . ALA B 1 208 ? -35.40861 38.21594 -26.67088 1.000 22.04255 ? 209 ALA B C   1 
ATOM   3836 O O   . ALA B 1 208 ? -35.50869 37.69785 -25.54798 1.000 24.13072 ? 209 ALA B O   1 
ATOM   3837 C CB  . ALA B 1 208 ? -35.47987 36.77975 -28.71662 1.000 23.41824 ? 209 ALA B CB  1 
ATOM   3838 N N   . TRP B 1 209 ? -34.54286 39.18516 -26.93803 1.000 23.22403 ? 210 TRP B N   1 
ATOM   3839 C CA  . TRP B 1 209 ? -33.63680 39.69397 -25.91614 1.000 26.89392 ? 210 TRP B CA  1 
ATOM   3840 C C   . TRP B 1 209 ? -34.39568 40.46125 -24.83516 1.000 26.17239 ? 210 TRP B C   1 
ATOM   3841 O O   . TRP B 1 209 ? -34.07975 40.34280 -23.65008 1.000 23.53613 ? 210 TRP B O   1 
ATOM   3842 C CB  . TRP B 1 209 ? -32.59019 40.57224 -26.58881 1.000 25.96064 ? 210 TRP B CB  1 
ATOM   3843 C CG  . TRP B 1 209 ? -31.65560 41.26321 -25.66540 1.000 28.31264 ? 210 TRP B CG  1 
ATOM   3844 C CD1 . TRP B 1 209 ? -30.67538 40.69461 -24.90310 1.000 28.45017 ? 210 TRP B CD1 1 
ATOM   3845 C CD2 . TRP B 1 209 ? -31.58754 42.66866 -25.43526 1.000 28.24723 ? 210 TRP B CD2 1 
ATOM   3846 N NE1 . TRP B 1 209 ? -30.00039 41.67249 -24.20250 1.000 29.02998 ? 210 TRP B NE1 1 
ATOM   3847 C CE2 . TRP B 1 209 ? -30.53912 42.89295 -24.51604 1.000 28.47712 ? 210 TRP B CE2 1 
ATOM   3848 C CE3 . TRP B 1 209 ? -32.30306 43.76867 -25.93171 1.000 31.87968 ? 210 TRP B CE3 1 
ATOM   3849 C CZ2 . TRP B 1 209 ? -30.19852 44.16584 -24.07253 1.000 33.79090 ? 210 TRP B CZ2 1 
ATOM   3850 C CZ3 . TRP B 1 209 ? -31.95730 45.04138 -25.49001 1.000 32.52743 ? 210 TRP B CZ3 1 
ATOM   3851 C CH2 . TRP B 1 209 ? -30.91703 45.22793 -24.57419 1.000 31.18630 ? 210 TRP B CH2 1 
ATOM   3852 N N   . LEU B 1 210 ? -35.41362 41.23824 -25.22235 1.000 24.12677 ? 211 LEU B N   1 
ATOM   3853 C CA  . LEU B 1 210 ? -36.26945 41.86448 -24.21724 1.000 25.70912 ? 211 LEU B CA  1 
ATOM   3854 C C   . LEU B 1 210 ? -36.98222 40.81477 -23.36605 1.000 25.95965 ? 211 LEU B C   1 
ATOM   3855 O O   . LEU B 1 210 ? -37.13437 40.99353 -22.15151 1.000 29.01253 ? 211 LEU B O   1 
ATOM   3856 C CB  . LEU B 1 210 ? -37.26177 42.81781 -24.89128 1.000 23.34712 ? 211 LEU B CB  1 
ATOM   3857 C CG  . LEU B 1 210 ? -36.60930 44.04882 -25.54447 1.000 28.51464 ? 211 LEU B CG  1 
ATOM   3858 C CD1 . LEU B 1 210 ? -37.62719 44.97561 -26.19715 1.000 26.23261 ? 211 LEU B CD1 1 
ATOM   3859 C CD2 . LEU B 1 210 ? -35.73901 44.82242 -24.54383 1.000 26.38478 ? 211 LEU B CD2 1 
ATOM   3860 N N   . TYR B 1 211 ? -37.40200 39.69885 -23.97046 1.000 24.13933 ? 212 TYR B N   1 
ATOM   3861 C CA  . TYR B 1 211 ? -38.00828 38.62488 -23.18266 1.000 25.32121 ? 212 TYR B CA  1 
ATOM   3862 C C   . TYR B 1 211 ? -36.99683 38.01362 -22.21275 1.000 28.97047 ? 212 TYR B C   1 
ATOM   3863 O O   . TYR B 1 211 ? -37.33708 37.70130 -21.06672 1.000 26.91610 ? 212 TYR B O   1 
ATOM   3864 C CB  . TYR B 1 211 ? -38.59482 37.53404 -24.09274 1.000 28.94042 ? 212 TYR B CB  1 
ATOM   3865 C CG  . TYR B 1 211 ? -40.02095 37.79809 -24.57700 1.000 26.31934 ? 212 TYR B CG  1 
ATOM   3866 C CD1 . TYR B 1 211 ? -41.07625 37.91306 -23.67397 1.000 27.55146 ? 212 TYR B CD1 1 
ATOM   3867 C CD2 . TYR B 1 211 ? -40.29942 37.92002 -25.93538 1.000 26.23185 ? 212 TYR B CD2 1 
ATOM   3868 C CE1 . TYR B 1 211 ? -42.37748 38.16867 -24.10647 1.000 29.71542 ? 212 TYR B CE1 1 
ATOM   3869 C CE2 . TYR B 1 211 ? -41.59393 38.17301 -26.38324 1.000 27.76428 ? 212 TYR B CE2 1 
ATOM   3870 C CZ  . TYR B 1 211 ? -42.62745 38.29924 -25.46030 1.000 30.78893 ? 212 TYR B CZ  1 
ATOM   3871 O OH  . TYR B 1 211 ? -43.90620 38.54140 -25.89749 1.000 31.15741 ? 212 TYR B OH  1 
ATOM   3872 N N   . ALA B 1 212 ? -35.75134 37.81330 -22.65618 1.000 27.03917 ? 213 ALA B N   1 
ATOM   3873 C CA  . ALA B 1 212 ? -34.73612 37.31118 -21.73185 1.000 24.95118 ? 213 ALA B CA  1 
ATOM   3874 C C   . ALA B 1 212 ? -34.51122 38.30123 -20.59311 1.000 25.61109 ? 213 ALA B C   1 
ATOM   3875 O O   . ALA B 1 212 ? -34.33790 37.90270 -19.43829 1.000 29.82348 ? 213 ALA B O   1 
ATOM   3876 C CB  . ALA B 1 212 ? -33.42945 37.03182 -22.47295 1.000 28.04916 ? 213 ALA B CB  1 
ATOM   3877 N N   . ALA B 1 213 ? -34.54534 39.59940 -20.90003 1.000 28.75282 ? 214 ALA B N   1 
ATOM   3878 C CA  . ALA B 1 213 ? -34.43710 40.61752 -19.85832 1.000 30.87133 ? 214 ALA B CA  1 
ATOM   3879 C C   . ALA B 1 213 ? -35.56639 40.49261 -18.84421 1.000 30.99082 ? 214 ALA B C   1 
ATOM   3880 O O   . ALA B 1 213 ? -35.32950 40.55484 -17.63179 1.000 31.23451 ? 214 ALA B O   1 
ATOM   3881 C CB  . ALA B 1 213 ? -34.43321 42.01123 -20.48124 1.000 29.58586 ? 214 ALA B CB  1 
ATOM   3882 N N   . ILE B 1 214 ? -36.80229 40.32030 -19.32451 1.000 28.86978 ? 215 ILE B N   1 
ATOM   3883 C CA  . ILE B 1 214 ? -37.94958 40.17942 -18.42983 1.000 31.66599 ? 215 ILE B CA  1 
ATOM   3884 C C   . ILE B 1 214 ? -37.80002 38.93287 -17.57354 1.000 32.47201 ? 215 ILE B C   1 
ATOM   3885 O O   . ILE B 1 214 ? -38.08529 38.95181 -16.36910 1.000 34.18762 ? 215 ILE B O   1 
ATOM   3886 C CB  . ILE B 1 214 ? -39.26490 40.16747 -19.24072 1.000 29.87220 ? 215 ILE B CB  1 
ATOM   3887 C CG1 . ILE B 1 214 ? -39.53982 41.55025 -19.83100 1.000 25.41286 ? 215 ILE B CG1 1 
ATOM   3888 C CG2 . ILE B 1 214 ? -40.43785 39.72576 -18.37407 1.000 30.68679 ? 215 ILE B CG2 1 
ATOM   3889 C CD1 . ILE B 1 214 ? -40.50064 41.52646 -21.01961 1.000 32.17897 ? 215 ILE B CD1 1 
ATOM   3890 N N   . LEU B 1 215 ? -37.33089 37.83381 -18.17384 1.000 31.07075 ? 216 LEU B N   1 
ATOM   3891 C CA  . LEU B 1 215 ? -37.14512 36.59729 -17.42353 1.000 32.08362 ? 216 LEU B CA  1 
ATOM   3892 C C   . LEU B 1 215 ? -36.09755 36.74418 -16.32715 1.000 35.56144 ? 216 LEU B C   1 
ATOM   3893 O O   . LEU B 1 215 ? -36.11680 35.97979 -15.35524 1.000 37.00566 ? 216 LEU B O   1 
ATOM   3894 C CB  . LEU B 1 215 ? -36.74385 35.46533 -18.37107 1.000 30.33770 ? 216 LEU B CB  1 
ATOM   3895 C CG  . LEU B 1 215 ? -37.85265 34.93496 -19.27684 1.000 30.93271 ? 216 LEU B CG  1 
ATOM   3896 C CD1 . LEU B 1 215 ? -37.28706 34.04003 -20.37291 1.000 29.86662 ? 216 LEU B CD1 1 
ATOM   3897 C CD2 . LEU B 1 215 ? -38.88613 34.18784 -18.45009 1.000 30.81018 ? 216 LEU B CD2 1 
ATOM   3898 N N   . ASN B 1 216 ? -35.17884 37.69828 -16.46551 1.000 34.98290 ? 217 ASN B N   1 
ATOM   3899 C CA  . ASN B 1 216 ? -34.14361 37.92925 -15.47222 1.000 39.33199 ? 217 ASN B CA  1 
ATOM   3900 C C   . ASN B 1 216 ? -34.46028 39.13021 -14.58554 1.000 39.10999 ? 217 ASN B C   1 
ATOM   3901 O O   . ASN B 1 216 ? -33.54666 39.74848 -14.03916 1.000 41.50167 ? 217 ASN B O   1 
ATOM   3902 C CB  . ASN B 1 216 ? -32.78089 38.09122 -16.15831 1.000 38.21851 ? 217 ASN B CB  1 
ATOM   3903 C CG  . ASN B 1 216 ? -32.26317 36.78109 -16.75262 1.000 45.97317 ? 217 ASN B CG  1 
ATOM   3904 O OD1 . ASN B 1 216 ? -31.94723 35.83709 -16.02615 1.000 47.64379 ? 217 ASN B OD1 1 
ATOM   3905 N ND2 . ASN B 1 216 ? -32.18459 36.71849 -18.08302 1.000 41.40007 ? 217 ASN B ND2 1 
ATOM   3906 N N   . GLY B 1 217 ? -35.73694 39.48137 -14.44801 1.000 39.50427 ? 218 GLY B N   1 
ATOM   3907 C CA  . GLY B 1 217 ? -36.13905 40.51503 -13.52104 1.000 36.20904 ? 218 GLY B CA  1 
ATOM   3908 C C   . GLY B 1 217 ? -35.98002 41.92864 -14.01550 1.000 42.57390 ? 218 GLY B C   1 
ATOM   3909 O O   . GLY B 1 217 ? -36.22179 42.86257 -13.24258 1.000 42.90182 ? 218 GLY B O   1 
ATOM   3910 N N   . CYS B 1 218 ? -35.58851 42.12620 -15.27511 1.000 36.68633 ? 219 CYS B N   1 
ATOM   3911 C CA  . CYS B 1 218 ? -35.37805 43.45994 -15.83470 1.000 36.80096 ? 219 CYS B CA  1 
ATOM   3912 C C   . CYS B 1 218 ? -36.52216 43.74978 -16.80516 1.000 40.50746 ? 219 CYS B C   1 
ATOM   3913 O O   . CYS B 1 218 ? -36.49943 43.29897 -17.95613 1.000 35.24670 ? 219 CYS B O   1 
ATOM   3914 C CB  . CYS B 1 218 ? -34.01988 43.55650 -16.52597 1.000 34.49276 ? 219 CYS B CB  1 
ATOM   3915 S SG  . CYS B 1 218 ? -33.70354 45.16910 -17.27733 1.000 39.48924 ? 219 CYS B SG  1 
ATOM   3916 N N   . ALA B 1 219 ? -37.51862 44.51887 -16.33603 1.000 39.84380 ? 220 ALA B N   1 
ATOM   3917 C CA  . ALA B 1 219 ? -38.74325 44.73589 -17.09771 1.000 37.15848 ? 220 ALA B CA  1 
ATOM   3918 C C   . ALA B 1 219 ? -39.25745 46.17040 -17.00407 1.000 36.21167 ? 220 ALA B C   1 
ATOM   3919 O O   . ALA B 1 219 ? -40.44310 46.40427 -17.26201 1.000 36.07875 ? 220 ALA B O   1 
ATOM   3920 C CB  . ALA B 1 219 ? -39.84782 43.76908 -16.62971 1.000 35.92402 ? 220 ALA B CB  1 
ATOM   3921 N N   . TRP B 1 220 ? -38.40036 47.13891 -16.66444 1.000 34.25939 ? 221 TRP B N   1 
ATOM   3922 C CA  . TRP B 1 220 ? -38.85013 48.52066 -16.50578 1.000 36.15485 ? 221 TRP B CA  1 
ATOM   3923 C C   . TRP B 1 220 ? -39.39055 49.11963 -17.79987 1.000 37.51520 ? 221 TRP B C   1 
ATOM   3924 O O   . TRP B 1 220 ? -40.10883 50.12621 -17.75493 1.000 37.01974 ? 221 TRP B O   1 
ATOM   3925 C CB  . TRP B 1 220 ? -37.69936 49.38713 -15.97844 1.000 37.55166 ? 221 TRP B CB  1 
ATOM   3926 C CG  . TRP B 1 220 ? -36.48965 49.40833 -16.90249 1.000 39.22851 ? 221 TRP B CG  1 
ATOM   3927 C CD1 . TRP B 1 220 ? -35.37151 48.62351 -16.81224 1.000 38.08242 ? 221 TRP B CD1 1 
ATOM   3928 C CD2 . TRP B 1 220 ? -36.29735 50.24678 -18.04950 1.000 36.19665 ? 221 TRP B CD2 1 
ATOM   3929 N NE1 . TRP B 1 220 ? -34.49653 48.92948 -17.83005 1.000 38.05747 ? 221 TRP B NE1 1 
ATOM   3930 C CE2 . TRP B 1 220 ? -35.04214 49.91983 -18.60216 1.000 36.94725 ? 221 TRP B CE2 1 
ATOM   3931 C CE3 . TRP B 1 220 ? -37.06385 51.24336 -18.66217 1.000 33.79402 ? 221 TRP B CE3 1 
ATOM   3932 C CZ2 . TRP B 1 220 ? -34.53923 50.55326 -19.73687 1.000 39.89161 ? 221 TRP B CZ2 1 
ATOM   3933 C CZ3 . TRP B 1 220 ? -36.56097 51.87187 -19.78574 1.000 38.15589 ? 221 TRP B CZ3 1 
ATOM   3934 C CH2 . TRP B 1 220 ? -35.31268 51.52534 -20.31208 1.000 37.66194 ? 221 TRP B CH2 1 
ATOM   3935 N N   . PHE B 1 221 ? -39.05113 48.54167 -18.95067 1.000 33.36742 ? 222 PHE B N   1 
ATOM   3936 C CA  . PHE B 1 221 ? -39.46405 49.06318 -20.24746 1.000 32.98172 ? 222 PHE B CA  1 
ATOM   3937 C C   . PHE B 1 221 ? -40.84832 48.58087 -20.67223 1.000 30.81824 ? 222 PHE B C   1 
ATOM   3938 O O   . PHE B 1 221 ? -41.32244 48.98516 -21.73703 1.000 31.33761 ? 222 PHE B O   1 
ATOM   3939 C CB  . PHE B 1 221 ? -38.43787 48.65481 -21.31064 1.000 31.97683 ? 222 PHE B CB  1 
ATOM   3940 C CG  . PHE B 1 221 ? -38.08110 47.19744 -21.24953 1.000 30.98030 ? 222 PHE B CG  1 
ATOM   3941 C CD1 . PHE B 1 221 ? -37.01574 46.75626 -20.46819 1.000 31.99699 ? 222 PHE B CD1 1 
ATOM   3942 C CD2 . PHE B 1 221 ? -38.83392 46.26557 -21.93906 1.000 29.22812 ? 222 PHE B CD2 1 
ATOM   3943 C CE1 . PHE B 1 221 ? -36.70271 45.41406 -20.38398 1.000 30.12045 ? 222 PHE B CE1 1 
ATOM   3944 C CE2 . PHE B 1 221 ? -38.52687 44.91678 -21.86861 1.000 27.93916 ? 222 PHE B CE2 1 
ATOM   3945 C CZ  . PHE B 1 221 ? -37.46172 44.48706 -21.08337 1.000 30.68785 ? 222 PHE B CZ  1 
ATOM   3946 N N   . VAL B 1 222 ? -41.48420 47.71017 -19.89804 1.000 31.38059 ? 223 VAL B N   1 
ATOM   3947 C CA  . VAL B 1 222 ? -42.77302 47.13898 -20.26892 1.000 33.22270 ? 223 VAL B CA  1 
ATOM   3948 C C   . VAL B 1 222 ? -43.86868 48.08918 -19.80086 1.000 36.24690 ? 223 VAL B C   1 
ATOM   3949 O O   . VAL B 1 222 ? -43.93720 48.43406 -18.61702 1.000 30.59567 ? 223 VAL B O   1 
ATOM   3950 C CB  . VAL B 1 222 ? -42.94969 45.73901 -19.66506 1.000 33.16988 ? 223 VAL B CB  1 
ATOM   3951 C CG1 . VAL B 1 222 ? -44.38080 45.22689 -19.86970 1.000 31.52818 ? 223 VAL B CG1 1 
ATOM   3952 C CG2 . VAL B 1 222 ? -41.94361 44.77365 -20.28551 1.000 33.29091 ? 223 VAL B CG2 1 
ATOM   3953 N N   . LYS B 1 223 ? -44.69865 48.54762 -20.73946 1.000 36.61961 ? 224 LYS B N   1 
ATOM   3954 C CA  . LYS B 1 223 ? -45.83636 49.41058 -20.42878 1.000 37.30949 ? 224 LYS B CA  1 
ATOM   3955 C C   . LYS B 1 223 ? -47.09769 48.76260 -21.00136 1.000 38.73716 ? 224 LYS B C   1 
ATOM   3956 O O   . LYS B 1 223 ? -46.98993 47.80119 -21.77662 1.000 34.25398 ? 224 LYS B O   1 
ATOM   3957 C CB  . LYS B 1 223 ? -45.62398 50.81927 -20.99387 1.000 37.59149 ? 224 LYS B CB  1 
ATOM   3958 C CG  . LYS B 1 223 ? -44.24487 51.41592 -20.72137 1.000 40.47017 ? 224 LYS B CG  1 
ATOM   3959 C CD  . LYS B 1 223 ? -44.23929 52.30983 -19.48722 1.000 46.95825 ? 224 LYS B CD  1 
ATOM   3960 C CE  . LYS B 1 223 ? -42.95409 52.14748 -18.65816 1.000 46.34865 ? 224 LYS B CE  1 
ATOM   3961 N NZ  . LYS B 1 223 ? -43.12584 52.56512 -17.23011 1.000 49.94398 ? 224 LYS B NZ  1 
ATOM   3962 N N   . PRO B 1 224 ? -48.30522 49.22987 -20.64475 1.000 37.64339 ? 225 PRO B N   1 
ATOM   3963 C CA  . PRO B 1 224 ? -49.51192 48.68255 -21.29316 1.000 34.95918 ? 225 PRO B CA  1 
ATOM   3964 C C   . PRO B 1 224 ? -49.60515 49.03535 -22.76578 1.000 32.19027 ? 225 PRO B C   1 
ATOM   3965 O O   . PRO B 1 224 ? -50.27698 48.31246 -23.51399 1.000 34.55607 ? 225 PRO B O   1 
ATOM   3966 C CB  . PRO B 1 224 ? -50.67317 49.32197 -20.50643 1.000 35.51345 ? 225 PRO B CB  1 
ATOM   3967 C CG  . PRO B 1 224 ? -50.06574 49.85515 -19.24627 1.000 39.42044 ? 225 PRO B CG  1 
ATOM   3968 C CD  . PRO B 1 224 ? -48.64360 50.20950 -19.59498 1.000 40.80290 ? 225 PRO B CD  1 
ATOM   3969 N N   . ASN B 1 225 ? -48.96416 50.12440 -23.19282 1.000 28.04961 ? 226 ASN B N   1 
ATOM   3970 C CA  . ASN B 1 225 ? -49.02515 50.56112 -24.58122 1.000 33.12335 ? 226 ASN B CA  1 
ATOM   3971 C C   . ASN B 1 225 ? -48.60849 49.43094 -25.51805 1.000 34.79112 ? 226 ASN B C   1 
ATOM   3972 O O   . ASN B 1 225 ? -47.71464 48.64639 -25.20507 1.000 30.42082 ? 226 ASN B O   1 
ATOM   3973 C CB  . ASN B 1 225 ? -48.11596 51.77451 -24.78745 1.000 33.76146 ? 226 ASN B CB  1 
ATOM   3974 C CG  . ASN B 1 225 ? -48.37747 52.88543 -23.77461 1.000 38.47458 ? 226 ASN B CG  1 
ATOM   3975 O OD1 . ASN B 1 225 ? -48.10798 52.74704 -22.57324 1.000 41.02921 ? 226 ASN B OD1 1 
ATOM   3976 N ND2 . ASN B 1 225 ? -48.90983 53.98720 -24.25914 1.000 38.31563 ? 226 ASN B ND2 1 
ATOM   3977 N N   . ARG B 1 226 ? -49.27582 49.34298 -26.66484 1.000 32.55310 ? 227 ARG B N   1 
ATOM   3978 C CA  . ARG B 1 226 ? -49.00437 48.31462 -27.65384 1.000 32.84151 ? 227 ARG B CA  1 
ATOM   3979 C C   . ARG B 1 226 ? -48.80635 48.95986 -29.01606 1.000 31.43375 ? 227 ARG B C   1 
ATOM   3980 O O   . ARG B 1 226 ? -49.38511 50.00641 -29.31656 1.000 34.77188 ? 227 ARG B O   1 
ATOM   3981 C CB  . ARG B 1 226 ? -50.15188 47.28685 -27.72750 1.000 34.57975 ? 227 ARG B CB  1 
ATOM   3982 C CG  . ARG B 1 226 ? -50.32594 46.42995 -26.46815 1.000 35.87915 ? 227 ARG B CG  1 
ATOM   3983 C CD  . ARG B 1 226 ? -51.67338 45.70668 -26.46882 1.000 38.27292 ? 227 ARG B CD  1 
ATOM   3984 N NE  . ARG B 1 226 ? -51.98479 45.14063 -27.78460 1.000 42.39069 ? 227 ARG B NE  1 
ATOM   3985 C CZ  . ARG B 1 226 ? -52.06179 43.83566 -28.03513 1.000 42.49326 ? 227 ARG B CZ  1 
ATOM   3986 N NH1 . ARG B 1 226 ? -51.85015 42.96024 -27.05444 1.000 37.21151 ? 227 ARG B NH1 1 
ATOM   3987 N NH2 . ARG B 1 226 ? -52.34394 43.40420 -29.26143 1.000 38.51286 ? 227 ARG B NH2 1 
ATOM   3988 N N   . THR B 1 227 ? -47.95670 48.34241 -29.82878 1.000 27.94145 ? 228 THR B N   1 
ATOM   3989 C CA  . THR B 1 227 ? -47.88225 48.62417 -31.25413 1.000 31.59793 ? 228 THR B CA  1 
ATOM   3990 C C   . THR B 1 227 ? -48.15214 47.31726 -31.98469 1.000 33.15196 ? 228 THR B C   1 
ATOM   3991 O O   . THR B 1 227 ? -47.49484 46.30619 -31.71892 1.000 28.47887 ? 228 THR B O   1 
ATOM   3992 C CB  . THR B 1 227 ? -46.52002 49.21107 -31.66193 1.000 27.71664 ? 228 THR B CB  1 
ATOM   3993 O OG1 . THR B 1 227 ? -46.30232 50.46097 -30.98881 1.000 31.12570 ? 228 THR B OG1 1 
ATOM   3994 C CG2 . THR B 1 227 ? -46.46792 49.46727 -33.17142 1.000 31.39936 ? 228 THR B CG2 1 
ATOM   3995 N N   . SER B 1 228 ? -49.14110 47.32643 -32.87121 1.000 33.17005 ? 229 SER B N   1 
ATOM   3996 C CA  . SER B 1 228 ? -49.44989 46.13565 -33.63481 1.000 28.71466 ? 229 SER B CA  1 
ATOM   3997 C C   . SER B 1 228 ? -48.28398 45.79066 -34.56223 1.000 31.02925 ? 229 SER B C   1 
ATOM   3998 O O   . SER B 1 228 ? -47.46213 46.64591 -34.92561 1.000 30.37316 ? 229 SER B O   1 
ATOM   3999 C CB  . SER B 1 228 ? -50.72677 46.35013 -34.45576 1.000 32.11835 ? 229 SER B CB  1 
ATOM   4000 O OG  . SER B 1 228 ? -50.43350 47.13833 -35.60235 1.000 27.78399 ? 229 SER B OG  1 
ATOM   4001 N N   . VAL B 1 229 ? -48.23709 44.51821 -34.97069 1.000 31.73545 ? 230 VAL B N   1 
ATOM   4002 C CA  . VAL B 1 229 ? -47.19846 44.06791 -35.89741 1.000 33.42934 ? 230 VAL B CA  1 
ATOM   4003 C C   . VAL B 1 229 ? -47.22236 44.89634 -37.17642 1.000 32.59906 ? 230 VAL B C   1 
ATOM   4004 O O   . VAL B 1 229 ? -46.17410 45.33923 -37.66125 1.000 29.88328 ? 230 VAL B O   1 
ATOM   4005 C CB  . VAL B 1 229 ? -47.35051 42.56088 -36.19539 1.000 34.65281 ? 230 VAL B CB  1 
ATOM   4006 C CG1 . VAL B 1 229 ? -46.37461 42.11805 -37.30995 1.000 32.15578 ? 230 VAL B CG1 1 
ATOM   4007 C CG2 . VAL B 1 229 ? -47.17255 41.73011 -34.90852 1.000 31.43046 ? 230 VAL B CG2 1 
ATOM   4008 N N   . VAL B 1 230 ? -48.41289 45.13290 -37.74231 1.000 33.43355 ? 231 VAL B N   1 
ATOM   4009 C CA  . VAL B 1 230 ? -48.47866 45.85826 -39.01257 1.000 33.03804 ? 231 VAL B CA  1 
ATOM   4010 C C   . VAL B 1 230 ? -47.98460 47.28965 -38.83451 1.000 31.74727 ? 231 VAL B C   1 
ATOM   4011 O O   . VAL B 1 230 ? -47.25175 47.82181 -39.67936 1.000 33.18152 ? 231 VAL B O   1 
ATOM   4012 C CB  . VAL B 1 230 ? -49.90614 45.81274 -39.59341 1.000 37.65697 ? 231 VAL B CB  1 
ATOM   4013 C CG1 . VAL B 1 230 ? -50.01242 46.70765 -40.83546 1.000 40.34755 ? 231 VAL B CG1 1 
ATOM   4014 C CG2 . VAL B 1 230 ? -50.28848 44.37859 -39.92521 1.000 36.96168 ? 231 VAL B CG2 1 
ATOM   4015 N N   . SER B 1 231 ? -48.34685 47.92528 -37.72023 1.000 34.02848 ? 232 SER B N   1 
ATOM   4016 C CA  . SER B 1 231 ? -47.88646 49.29066 -37.47249 1.000 34.27199 ? 232 SER B CA  1 
ATOM   4017 C C   . SER B 1 231 ? -46.38176 49.32911 -37.22863 1.000 34.27845 ? 232 SER B C   1 
ATOM   4018 O O   . SER B 1 231 ? -45.67273 50.18785 -37.77744 1.000 31.03796 ? 232 SER B O   1 
ATOM   4019 C CB  . SER B 1 231 ? -48.64372 49.89190 -36.28818 1.000 37.22255 ? 232 SER B CB  1 
ATOM   4020 O OG  . SER B 1 231 ? -49.95422 50.26041 -36.68135 1.000 43.73792 ? 232 SER B OG  1 
ATOM   4021 N N   . PHE B 1 232 ? -45.87986 48.40682 -36.39499 1.000 33.54499 ? 233 PHE B N   1 
ATOM   4022 C CA  . PHE B 1 232 ? -44.43993 48.30321 -36.18545 1.000 28.99858 ? 233 PHE B CA  1 
ATOM   4023 C C   . PHE B 1 232 ? -43.70911 48.14191 -37.50603 1.000 28.22891 ? 233 PHE B C   1 
ATOM   4024 O O   . PHE B 1 232 ? -42.70204 48.81437 -37.75473 1.000 28.74853 ? 233 PHE B O   1 
ATOM   4025 C CB  . PHE B 1 232 ? -44.10832 47.12507 -35.26176 1.000 29.50322 ? 233 PHE B CB  1 
ATOM   4026 C CG  . PHE B 1 232 ? -42.63165 46.98032 -35.00789 1.000 30.54699 ? 233 PHE B CG  1 
ATOM   4027 C CD1 . PHE B 1 232 ? -41.99830 47.77508 -34.05571 1.000 27.33123 ? 233 PHE B CD1 1 
ATOM   4028 C CD2 . PHE B 1 232 ? -41.86034 46.10370 -35.77101 1.000 29.14166 ? 233 PHE B CD2 1 
ATOM   4029 C CE1 . PHE B 1 232 ? -40.63644 47.67782 -33.85026 1.000 29.77852 ? 233 PHE B CE1 1 
ATOM   4030 C CE2 . PHE B 1 232 ? -40.49228 45.99719 -35.56093 1.000 28.90875 ? 233 PHE B CE2 1 
ATOM   4031 C CZ  . PHE B 1 232 ? -39.88038 46.78062 -34.60299 1.000 28.12716 ? 233 PHE B CZ  1 
ATOM   4032 N N   . ASN B 1 233 ? -44.22137 47.26471 -38.37958 1.000 31.60746 ? 234 ASN B N   1 
ATOM   4033 C CA  . ASN B 1 233 ? -43.49822 46.91670 -39.60080 1.000 31.72158 ? 234 ASN B CA  1 
ATOM   4034 C C   . ASN B 1 233 ? -43.41011 48.09536 -40.55930 1.000 32.03284 ? 234 ASN B C   1 
ATOM   4035 O O   . ASN B 1 233 ? -42.37458 48.29836 -41.21048 1.000 32.06186 ? 234 ASN B O   1 
ATOM   4036 C CB  . ASN B 1 233 ? -44.14725 45.69972 -40.26519 1.000 32.34454 ? 234 ASN B CB  1 
ATOM   4037 C CG  . ASN B 1 233 ? -43.77304 44.41507 -39.56173 1.000 31.95216 ? 234 ASN B CG  1 
ATOM   4038 O OD1 . ASN B 1 233 ? -42.85740 44.41202 -38.74319 1.000 30.55372 ? 234 ASN B OD1 1 
ATOM   4039 N ND2 . ASN B 1 233 ? -44.47394 43.32389 -39.86045 1.000 32.46362 ? 234 ASN B ND2 1 
ATOM   4040 N N   . GLU B 1 234 ? -44.46519 48.90451 -40.64612 1.000 31.32433 ? 235 GLU B N   1 
ATOM   4041 C CA  . GLU B 1 234 ? -44.33503 50.13038 -41.42814 1.000 32.58874 ? 235 GLU B CA  1 
ATOM   4042 C C   . GLU B 1 234 ? -43.33734 51.09392 -40.78377 1.000 31.00318 ? 235 GLU B C   1 
ATOM   4043 O O   . GLU B 1 234 ? -42.51450 51.70601 -41.47511 1.000 31.96254 ? 235 GLU B O   1 
ATOM   4044 C CB  . GLU B 1 234 ? -45.70602 50.77487 -41.60543 1.000 38.42462 ? 235 GLU B CB  1 
ATOM   4045 C CG  . GLU B 1 234 ? -46.52212 50.08047 -42.69066 1.000 47.77648 ? 235 GLU B CG  1 
ATOM   4046 C CD  . GLU B 1 234 ? -47.80135 50.82163 -43.01491 1.000 51.21494 ? 235 GLU B CD  1 
ATOM   4047 O OE1 . GLU B 1 234 ? -47.77238 52.07791 -42.99681 1.000 48.34368 ? 235 GLU B OE1 1 
ATOM   4048 O OE2 . GLU B 1 234 ? -48.82521 50.15073 -43.29874 1.000 52.33543 ? 235 GLU B OE2 1 
ATOM   4049 N N   . TRP B 1 235 ? -43.38145 51.23566 -39.45763 1.000 30.01846 ? 236 TRP B N   1 
ATOM   4050 C CA  . TRP B 1 235 ? -42.36785 52.03681 -38.76806 1.000 32.57090 ? 236 TRP B CA  1 
ATOM   4051 C C   . TRP B 1 235 ? -40.96721 51.50509 -39.04715 1.000 33.39872 ? 236 TRP B C   1 
ATOM   4052 O O   . TRP B 1 235 ? -40.02504 52.28184 -39.25630 1.000 31.06107 ? 236 TRP B O   1 
ATOM   4053 C CB  . TRP B 1 235 ? -42.63520 52.03600 -37.26039 1.000 32.28384 ? 236 TRP B CB  1 
ATOM   4054 C CG  . TRP B 1 235 ? -41.58101 52.72899 -36.44455 1.000 32.45498 ? 236 TRP B CG  1 
ATOM   4055 C CD1 . TRP B 1 235 ? -41.49595 54.07214 -36.19615 1.000 36.96918 ? 236 TRP B CD1 1 
ATOM   4056 C CD2 . TRP B 1 235 ? -40.47894 52.12183 -35.74006 1.000 35.55240 ? 236 TRP B CD2 1 
ATOM   4057 N NE1 . TRP B 1 235 ? -40.40825 54.33983 -35.39295 1.000 39.16735 ? 236 TRP B NE1 1 
ATOM   4058 C CE2 . TRP B 1 235 ? -39.76812 53.16407 -35.09761 1.000 34.04218 ? 236 TRP B CE2 1 
ATOM   4059 C CE3 . TRP B 1 235 ? -40.02138 50.80242 -35.59399 1.000 33.05243 ? 236 TRP B CE3 1 
ATOM   4060 C CZ2 . TRP B 1 235 ? -38.62952 52.93055 -34.32079 1.000 35.73647 ? 236 TRP B CZ2 1 
ATOM   4061 C CZ3 . TRP B 1 235 ? -38.88613 50.57378 -34.82270 1.000 32.01116 ? 236 TRP B CZ3 1 
ATOM   4062 C CH2 . TRP B 1 235 ? -38.20070 51.63350 -34.19935 1.000 34.92539 ? 236 TRP B CH2 1 
ATOM   4063 N N   . ALA B 1 236 ? -40.81982 50.17517 -39.06549 1.000 31.44883 ? 237 ALA B N   1 
ATOM   4064 C CA  . ALA B 1 236 ? -39.50131 49.56547 -39.19014 1.000 30.06553 ? 237 ALA B CA  1 
ATOM   4065 C C   . ALA B 1 236 ? -38.82759 49.93817 -40.49777 1.000 33.47327 ? 237 ALA B C   1 
ATOM   4066 O O   . ALA B 1 236 ? -37.59645 50.07465 -40.54326 1.000 31.85923 ? 237 ALA B O   1 
ATOM   4067 C CB  . ALA B 1 236 ? -39.61710 48.04796 -39.06531 1.000 29.75983 ? 237 ALA B CB  1 
ATOM   4068 N N   . LEU B 1 237 ? -39.61266 50.11133 -41.56749 1.000 35.76054 ? 238 LEU B N   1 
ATOM   4069 C CA  . LEU B 1 237 ? -39.04543 50.44053 -42.87069 1.000 35.88766 ? 238 LEU B CA  1 
ATOM   4070 C C   . LEU B 1 237 ? -38.30571 51.76480 -42.86479 1.000 37.15215 ? 238 LEU B C   1 
ATOM   4071 O O   . LEU B 1 237 ? -37.39491 51.96201 -43.67887 1.000 36.63885 ? 238 LEU B O   1 
ATOM   4072 C CB  . LEU B 1 237 ? -40.15488 50.46152 -43.92545 1.000 39.42487 ? 238 LEU B CB  1 
ATOM   4073 C CG  . LEU B 1 237 ? -40.33303 49.12099 -44.63056 1.000 41.08973 ? 238 LEU B CG  1 
ATOM   4074 C CD1 . LEU B 1 237 ? -41.73772 48.98583 -45.20855 1.000 46.37467 ? 238 LEU B CD1 1 
ATOM   4075 C CD2 . LEU B 1 237 ? -39.27163 48.97645 -45.70999 1.000 41.99938 ? 238 LEU B CD2 1 
ATOM   4076 N N   . ALA B 1 238 ? -38.67093 52.67254 -41.97206 1.000 34.72359 ? 239 ALA B N   1 
ATOM   4077 C CA  . ALA B 1 238 ? -38.06053 53.98756 -41.92045 1.000 35.53110 ? 239 ALA B CA  1 
ATOM   4078 C C   . ALA B 1 238 ? -37.02218 54.11716 -40.81714 1.000 38.44235 ? 239 ALA B C   1 
ATOM   4079 O O   . ALA B 1 238 ? -36.40484 55.18066 -40.69048 1.000 38.20642 ? 239 ALA B O   1 
ATOM   4080 C CB  . ALA B 1 238 ? -39.14231 55.05654 -41.73875 1.000 37.83891 ? 239 ALA B CB  1 
ATOM   4081 N N   . ASN B 1 239 ? -36.80189 53.06326 -40.02202 1.000 34.17286 ? 240 ASN B N   1 
ATOM   4082 C CA  . ASN B 1 239 ? -35.98369 53.19447 -38.82120 1.000 34.89409 ? 240 ASN B CA  1 
ATOM   4083 C C   . ASN B 1 239 ? -34.99085 52.03936 -38.64940 1.000 37.77152 ? 240 ASN B C   1 
ATOM   4084 O O   . ASN B 1 239 ? -34.62184 51.70261 -37.51554 1.000 35.00034 ? 240 ASN B O   1 
ATOM   4085 C CB  . ASN B 1 239 ? -36.86936 53.31285 -37.58181 1.000 33.07476 ? 240 ASN B CB  1 
ATOM   4086 C CG  . ASN B 1 239 ? -37.61539 54.63873 -37.52759 1.000 36.67205 ? 240 ASN B CG  1 
ATOM   4087 O OD1 . ASN B 1 239 ? -38.81266 54.69919 -37.81588 1.000 36.00621 ? 240 ASN B OD1 1 
ATOM   4088 N ND2 . ASN B 1 239 ? -36.90779 55.70607 -37.16940 1.000 32.67446 ? 240 ASN B ND2 1 
ATOM   4089 N N   . GLN B 1 240 ? -34.55164 51.42724 -39.75679 1.000 34.61674 ? 241 GLN B N   1 
ATOM   4090 C CA  . GLN B 1 240 ? -33.46512 50.44482 -39.74945 1.000 36.91173 ? 241 GLN B CA  1 
ATOM   4091 C C   . GLN B 1 240 ? -33.78708 49.20432 -38.91788 1.000 32.83020 ? 241 GLN B C   1 
ATOM   4092 O O   . GLN B 1 240 ? -32.89567 48.63790 -38.27806 1.000 32.95835 ? 241 GLN B O   1 
ATOM   4093 C CB  . GLN B 1 240 ? -32.15713 51.05412 -39.23881 1.000 42.29146 ? 241 GLN B CB  1 
ATOM   4094 C CG  . GLN B 1 240 ? -31.76378 52.39274 -39.82409 1.000 45.79772 ? 241 GLN B CG  1 
ATOM   4095 C CD  . GLN B 1 240 ? -30.51022 52.92950 -39.16417 1.000 50.93714 ? 241 GLN B CD  1 
ATOM   4096 O OE1 . GLN B 1 240 ? -29.46037 53.04172 -39.79991 1.000 56.52025 ? 241 GLN B OE1 1 
ATOM   4097 N NE2 . GLN B 1 240 ? -30.60721 53.24569 -37.87329 1.000 51.57484 ? 241 GLN B NE2 1 
ATOM   4098 N N   . PHE B 1 241 ? -35.04650 48.77347 -38.89133 1.000 30.70172 ? 242 PHE B N   1 
ATOM   4099 C CA  . PHE B 1 241 ? -35.40535 47.48536 -38.31238 1.000 31.40641 ? 242 PHE B CA  1 
ATOM   4100 C C   . PHE B 1 241 ? -35.96965 46.57551 -39.39297 1.000 32.39028 ? 242 PHE B C   1 
ATOM   4101 O O   . PHE B 1 241 ? -36.60751 47.04028 -40.34584 1.000 29.53970 ? 242 PHE B O   1 
ATOM   4102 C CB  . PHE B 1 241 ? -36.43606 47.62447 -37.18681 1.000 27.12171 ? 242 PHE B CB  1 
ATOM   4103 C CG  . PHE B 1 241 ? -35.84376 48.06754 -35.88866 1.000 27.68382 ? 242 PHE B CG  1 
ATOM   4104 C CD1 . PHE B 1 241 ? -35.41223 49.37188 -35.72476 1.000 30.01320 ? 242 PHE B CD1 1 
ATOM   4105 C CD2 . PHE B 1 241 ? -35.71218 47.18525 -34.83981 1.000 28.96169 ? 242 PHE B CD2 1 
ATOM   4106 C CE1 . PHE B 1 241 ? -34.86123 49.78475 -34.53093 1.000 33.89128 ? 242 PHE B CE1 1 
ATOM   4107 C CE2 . PHE B 1 241 ? -35.16669 47.58982 -33.63844 1.000 29.94918 ? 242 PHE B CE2 1 
ATOM   4108 C CZ  . PHE B 1 241 ? -34.73837 48.88490 -33.48136 1.000 30.78642 ? 242 PHE B CZ  1 
ATOM   4109 N N   . THR B 1 242 ? -35.73447 45.27331 -39.23932 1.000 28.94716 ? 243 THR B N   1 
ATOM   4110 C CA  . THR B 1 242 ? -36.39865 44.31457 -40.10961 1.000 29.40293 ? 243 THR B CA  1 
ATOM   4111 C C   . THR B 1 242 ? -37.87338 44.20830 -39.74738 1.000 28.51813 ? 243 THR B C   1 
ATOM   4112 O O   . THR B 1 242 ? -38.30425 44.59071 -38.65944 1.000 25.08935 ? 243 THR B O   1 
ATOM   4113 C CB  . THR B 1 242 ? -35.77908 42.92091 -40.00185 1.000 30.25813 ? 243 THR B CB  1 
ATOM   4114 O OG1 . THR B 1 242 ? -35.98853 42.41002 -38.67544 1.000 26.15797 ? 243 THR B OG1 1 
ATOM   4115 C CG2 . THR B 1 242 ? -34.30160 42.96586 -40.33924 1.000 29.09876 ? 243 THR B CG2 1 
ATOM   4116 N N   . GLU B 1 243 ? -38.64909 43.67217 -40.68114 1.000 29.52741 ? 244 GLU B N   1 
ATOM   4117 C CA  . GLU B 1 243 ? -40.03928 43.36532 -40.38704 1.000 31.59978 ? 244 GLU B CA  1 
ATOM   4118 C C   . GLU B 1 243 ? -40.11467 42.28715 -39.31015 1.000 33.39880 ? 244 GLU B C   1 
ATOM   4119 O O   . GLU B 1 243 ? -39.27361 41.38171 -39.25101 1.000 32.17819 ? 244 GLU B O   1 
ATOM   4120 C CB  . GLU B 1 243 ? -40.74547 42.92342 -41.67033 1.000 36.82896 ? 244 GLU B CB  1 
ATOM   4121 C CG  . GLU B 1 243 ? -41.76138 41.81672 -41.52453 1.000 42.89504 ? 244 GLU B CG  1 
ATOM   4122 C CD  . GLU B 1 243 ? -42.41000 41.47317 -42.85748 1.000 49.35845 ? 244 GLU B CD  1 
ATOM   4123 O OE1 . GLU B 1 243 ? -42.05044 40.41986 -43.43139 1.000 52.84536 ? 244 GLU B OE1 1 
ATOM   4124 O OE2 . GLU B 1 243 ? -43.25827 42.26286 -43.33456 1.000 55.01339 ? 244 GLU B OE2 1 
ATOM   4125 N N   . PHE B 1 244 ? -41.10258 42.40822 -38.43144 1.000 29.11409 ? 245 PHE B N   1 
ATOM   4126 C CA  . PHE B 1 244 ? -41.32517 41.41440 -37.39569 1.000 32.11424 ? 245 PHE B CA  1 
ATOM   4127 C C   . PHE B 1 244 ? -42.21640 40.30568 -37.93671 1.000 31.14132 ? 245 PHE B C   1 
ATOM   4128 O O   . PHE B 1 244 ? -43.31300 40.57666 -38.43023 1.000 28.07573 ? 245 PHE B O   1 
ATOM   4129 C CB  . PHE B 1 244 ? -41.97395 42.02781 -36.15422 1.000 26.83432 ? 245 PHE B CB  1 
ATOM   4130 C CG  . PHE B 1 244 ? -42.26334 41.01366 -35.08502 1.000 29.27230 ? 245 PHE B CG  1 
ATOM   4131 C CD1 . PHE B 1 244 ? -41.29108 40.67264 -34.16357 1.000 29.27995 ? 245 PHE B CD1 1 
ATOM   4132 C CD2 . PHE B 1 244 ? -43.48786 40.36273 -35.03046 1.000 27.60070 ? 245 PHE B CD2 1 
ATOM   4133 C CE1 . PHE B 1 244 ? -41.54159 39.71956 -33.19442 1.000 28.06465 ? 245 PHE B CE1 1 
ATOM   4134 C CE2 . PHE B 1 244 ? -43.73679 39.40505 -34.07116 1.000 29.27139 ? 245 PHE B CE2 1 
ATOM   4135 C CZ  . PHE B 1 244 ? -42.76310 39.08075 -33.15391 1.000 28.67054 ? 245 PHE B CZ  1 
ATOM   4136 N N   . VAL B 1 245 ? -41.75589 39.06186 -37.81534 1.000 31.70611 ? 246 VAL B N   1 
ATOM   4137 C CA  . VAL B 1 245 ? -42.55474 37.87607 -38.12512 1.000 29.82893 ? 246 VAL B CA  1 
ATOM   4138 C C   . VAL B 1 245 ? -42.57472 36.99482 -36.88267 1.000 29.89542 ? 246 VAL B C   1 
ATOM   4139 O O   . VAL B 1 245 ? -41.51937 36.55033 -36.41115 1.000 28.54225 ? 246 VAL B O   1 
ATOM   4140 C CB  . VAL B 1 245 ? -42.00869 37.11036 -39.34216 1.000 29.94123 ? 246 VAL B CB  1 
ATOM   4141 C CG1 . VAL B 1 245 ? -42.90354 35.89718 -39.66768 1.000 30.66454 ? 246 VAL B CG1 1 
ATOM   4142 C CG2 . VAL B 1 245 ? -41.90314 38.03500 -40.54666 1.000 34.09406 ? 246 VAL B CG2 1 
ATOM   4143 N N   . GLY B 1 246 ? -43.76782 36.76793 -36.33384 1.000 27.13110 ? 247 GLY B N   1 
ATOM   4144 C CA  . GLY B 1 246 ? -43.88012 35.95827 -35.14263 1.000 28.62513 ? 247 GLY B CA  1 
ATOM   4145 C C   . GLY B 1 246 ? -43.65495 34.48913 -35.43588 1.000 29.01977 ? 247 GLY B C   1 
ATOM   4146 O O   . GLY B 1 246 ? -43.80281 34.02296 -36.56263 1.000 27.92188 ? 247 GLY B O   1 
ATOM   4147 N N   . THR B 1 247 ? -43.26303 33.75348 -34.39841 1.000 29.53492 ? 248 THR B N   1 
ATOM   4148 C CA  . THR B 1 247 ? -43.05511 32.31449 -34.49239 1.000 28.64395 ? 248 THR B CA  1 
ATOM   4149 C C   . THR B 1 247 ? -43.58188 31.65700 -33.22396 1.000 30.39685 ? 248 THR B C   1 
ATOM   4150 O O   . THR B 1 247 ? -43.86506 32.32178 -32.22365 1.000 27.77185 ? 248 THR B O   1 
ATOM   4151 C CB  . THR B 1 247 ? -41.57049 31.94402 -34.68985 1.000 30.39048 ? 248 THR B CB  1 
ATOM   4152 O OG1 . THR B 1 247 ? -40.83825 32.25904 -33.49514 1.000 31.63940 ? 248 THR B OG1 1 
ATOM   4153 C CG2 . THR B 1 247 ? -40.95111 32.67997 -35.88549 1.000 29.75210 ? 248 THR B CG2 1 
ATOM   4154 N N   . GLN B 1 248 ? -43.69784 30.32501 -33.26544 1.000 30.41616 ? 249 GLN B N   1 
ATOM   4155 C CA  . GLN B 1 248 ? -44.11706 29.59533 -32.07263 1.000 31.00453 ? 249 GLN B CA  1 
ATOM   4156 C C   . GLN B 1 248 ? -43.10806 29.74968 -30.94029 1.000 30.99092 ? 249 GLN B C   1 
ATOM   4157 O O   . GLN B 1 248 ? -43.48891 29.75611 -29.76772 1.000 31.15827 ? 249 GLN B O   1 
ATOM   4158 C CB  . GLN B 1 248 ? -44.32976 28.11045 -32.39628 1.000 33.65967 ? 249 GLN B CB  1 
ATOM   4159 C CG  . GLN B 1 248 ? -44.55578 27.24894 -31.15088 1.000 40.60135 ? 249 GLN B CG  1 
ATOM   4160 C CD  . GLN B 1 248 ? -45.84626 26.46270 -31.20534 1.000 48.75006 ? 249 GLN B CD  1 
ATOM   4161 O OE1 . GLN B 1 248 ? -46.33136 26.10909 -32.28676 1.000 54.35967 ? 249 GLN B OE1 1 
ATOM   4162 N NE2 . GLN B 1 248 ? -46.42072 26.19046 -30.03657 1.000 45.76403 ? 249 GLN B NE2 1 
ATOM   4163 N N   . SER B 1 249 ? -41.82309 29.88408 -31.26809 1.000 28.20448 ? 250 SER B N   1 
ATOM   4164 C CA  . SER B 1 249 ? -40.82627 30.13381 -30.23288 1.000 31.09125 ? 250 SER B CA  1 
ATOM   4165 C C   . SER B 1 249 ? -41.09136 31.45565 -29.51438 1.000 25.82095 ? 250 SER B C   1 
ATOM   4166 O O   . SER B 1 249 ? -41.04353 31.52124 -28.28118 1.000 31.92224 ? 250 SER B O   1 
ATOM   4167 C CB  . SER B 1 249 ? -39.42594 30.11600 -30.84866 1.000 32.01252 ? 250 SER B CB  1 
ATOM   4168 O OG  . SER B 1 249 ? -38.43503 29.99218 -29.84536 1.000 37.87158 ? 250 SER B OG  1 
ATOM   4169 N N   . VAL B 1 250 ? -41.36690 32.52844 -30.26573 1.000 29.89287 ? 251 VAL B N   1 
ATOM   4170 C CA  . VAL B 1 250 ? -41.67696 33.80726 -29.61914 1.000 29.58134 ? 251 VAL B CA  1 
ATOM   4171 C C   . VAL B 1 250 ? -42.90721 33.66660 -28.73027 1.000 30.31724 ? 251 VAL B C   1 
ATOM   4172 O O   . VAL B 1 250 ? -42.95591 34.21397 -27.61995 1.000 26.92168 ? 251 VAL B O   1 
ATOM   4173 C CB  . VAL B 1 250 ? -41.86899 34.92511 -30.66197 1.000 31.08567 ? 251 VAL B CB  1 
ATOM   4174 C CG1 . VAL B 1 250 ? -42.17941 36.25769 -29.95503 1.000 29.42035 ? 251 VAL B CG1 1 
ATOM   4175 C CG2 . VAL B 1 250 ? -40.63368 35.06915 -31.54391 1.000 27.32981 ? 251 VAL B CG2 1 
ATOM   4176 N N   . ASP B 1 251 ? -43.91600 32.92706 -29.20886 1.000 30.98645 ? 252 ASP B N   1 
ATOM   4177 C CA  . ASP B 1 251 ? -45.15911 32.74744 -28.46200 1.000 33.54128 ? 252 ASP B CA  1 
ATOM   4178 C C   . ASP B 1 251 ? -44.90185 32.12775 -27.09675 1.000 31.89658 ? 252 ASP B C   1 
ATOM   4179 O O   . ASP B 1 251 ? -45.54714 32.49616 -26.10616 1.000 32.36537 ? 252 ASP B O   1 
ATOM   4180 C CB  . ASP B 1 251 ? -46.13099 31.85757 -29.24458 1.000 35.46279 ? 252 ASP B CB  1 
ATOM   4181 C CG  . ASP B 1 251 ? -46.73338 32.54440 -30.47355 1.000 37.46580 ? 252 ASP B CG  1 
ATOM   4182 O OD1 . ASP B 1 251 ? -46.65543 33.78656 -30.61608 1.000 33.33201 ? 252 ASP B OD1 1 
ATOM   4183 O OD2 . ASP B 1 251 ? -47.31676 31.81426 -31.30193 1.000 38.77403 ? 252 ASP B OD2 1 
ATOM   4184 N N   . MET B 1 252 ? -43.98263 31.16030 -27.02961 1.000 31.92507 ? 253 MET B N   1 
ATOM   4185 C CA  . MET B 1 252 ? -43.67873 30.52808 -25.75282 1.000 31.44279 ? 253 MET B CA  1 
ATOM   4186 C C   . MET B 1 252 ? -43.08921 31.52935 -24.76442 1.000 32.73080 ? 253 MET B C   1 
ATOM   4187 O O   . MET B 1 252 ? -43.37615 31.46405 -23.56474 1.000 30.82919 ? 253 MET B O   1 
ATOM   4188 C CB  . MET B 1 252 ? -42.73240 29.34680 -25.96085 1.000 34.24756 ? 253 MET B CB  1 
ATOM   4189 C CG  . MET B 1 252 ? -43.37698 28.14291 -26.63175 1.000 42.02342 ? 253 MET B CG  1 
ATOM   4190 S SD  . MET B 1 252 ? -42.27190 26.71896 -26.59201 1.000 60.41914 ? 253 MET B SD  1 
ATOM   4191 C CE  . MET B 1 252 ? -41.44064 26.98221 -25.01976 1.000 43.60748 ? 253 MET B CE  1 
ATOM   4192 N N   . LEU B 1 253 ? -42.26110 32.46249 -25.24849 1.000 31.15200 ? 254 LEU B N   1 
ATOM   4193 C CA  . LEU B 1 253 ? -41.75918 33.52255 -24.37714 1.000 30.65958 ? 254 LEU B CA  1 
ATOM   4194 C C   . LEU B 1 253 ? -42.89198 34.42154 -23.90053 1.000 30.21557 ? 254 LEU B C   1 
ATOM   4195 O O   . LEU B 1 253 ? -42.89635 34.86665 -22.74723 1.000 30.82319 ? 254 LEU B O   1 
ATOM   4196 C CB  . LEU B 1 253 ? -40.69770 34.34698 -25.09750 1.000 28.29725 ? 254 LEU B CB  1 
ATOM   4197 C CG  . LEU B 1 253 ? -39.44562 33.57668 -25.51779 1.000 28.88241 ? 254 LEU B CG  1 
ATOM   4198 C CD1 . LEU B 1 253 ? -38.47094 34.49697 -26.27003 1.000 24.49905 ? 254 LEU B CD1 1 
ATOM   4199 C CD2 . LEU B 1 253 ? -38.78761 32.94686 -24.30178 1.000 29.99629 ? 254 LEU B CD2 1 
ATOM   4200 N N   . ALA B 1 254 ? -43.86511 34.69926 -24.77510 1.000 29.68460 ? 255 ALA B N   1 
ATOM   4201 C CA  . ALA B 1 254 ? -45.00048 35.52075 -24.36774 1.000 33.04846 ? 255 ALA B CA  1 
ATOM   4202 C C   . ALA B 1 254 ? -45.78360 34.84602 -23.25042 1.000 33.57904 ? 255 ALA B C   1 
ATOM   4203 O O   . ALA B 1 254 ? -46.20907 35.50627 -22.29491 1.000 34.03842 ? 255 ALA B O   1 
ATOM   4204 C CB  . ALA B 1 254 ? -45.90766 35.80449 -25.56449 1.000 29.41633 ? 255 ALA B CB  1 
ATOM   4205 N N   . VAL B 1 255 ? -45.96389 33.52517 -23.34743 1.000 34.45947 ? 256 VAL B N   1 
ATOM   4206 C CA  . VAL B 1 255 ? -46.70248 32.78087 -22.32752 1.000 36.89575 ? 256 VAL B CA  1 
ATOM   4207 C C   . VAL B 1 255 ? -45.95314 32.78446 -21.00174 1.000 38.60157 ? 256 VAL B C   1 
ATOM   4208 O O   . VAL B 1 255 ? -46.54680 33.00728 -19.94141 1.000 40.09067 ? 256 VAL B O   1 
ATOM   4209 C CB  . VAL B 1 255 ? -46.97396 31.34440 -22.80833 1.000 38.14905 ? 256 VAL B CB  1 
ATOM   4210 C CG1 . VAL B 1 255 ? -47.67530 30.54403 -21.72252 1.000 40.61796 ? 256 VAL B CG1 1 
ATOM   4211 C CG2 . VAL B 1 255 ? -47.79627 31.36712 -24.07170 1.000 34.87191 ? 256 VAL B CG2 1 
ATOM   4212 N N   . LYS B 1 256 ? -44.64329 32.52435 -21.03622 1.000 38.14188 ? 257 LYS B N   1 
ATOM   4213 C CA  . LYS B 1 256 ? -43.87139 32.41961 -19.80148 1.000 35.25565 ? 257 LYS B CA  1 
ATOM   4214 C C   . LYS B 1 256 ? -43.87361 33.73067 -19.02246 1.000 35.74383 ? 257 LYS B C   1 
ATOM   4215 O O   . LYS B 1 256 ? -43.89049 33.72681 -17.79008 1.000 38.61747 ? 257 LYS B O   1 
ATOM   4216 C CB  . LYS B 1 256 ? -42.43565 31.99321 -20.11499 1.000 36.45319 ? 257 LYS B CB  1 
ATOM   4217 C CG  . LYS B 1 256 ? -42.29488 30.52656 -20.46595 1.000 40.02788 ? 257 LYS B CG  1 
ATOM   4218 C CD  . LYS B 1 256 ? -40.86518 30.04173 -20.30278 1.000 44.82756 ? 257 LYS B CD  1 
ATOM   4219 C CE  . LYS B 1 256 ? -40.06090 30.27282 -21.57146 1.000 36.88675 ? 257 LYS B CE  1 
ATOM   4220 N NZ  . LYS B 1 256 ? -39.12754 29.13421 -21.79325 1.000 46.37982 ? 257 LYS B NZ  1 
ATOM   4221 N N   . THR B 1 257 ? -43.85973 34.85992 -19.72021 1.000 34.48652 ? 258 THR B N   1 
ATOM   4222 C CA  . THR B 1 257 ? -43.71296 36.15551 -19.07243 1.000 34.19020 ? 258 THR B CA  1 
ATOM   4223 C C   . THR B 1 257 ? -45.02667 36.90856 -18.92210 1.000 35.66766 ? 258 THR B C   1 
ATOM   4224 O O   . THR B 1 257 ? -45.09107 37.85600 -18.12926 1.000 37.32202 ? 258 THR B O   1 
ATOM   4225 C CB  . THR B 1 257 ? -42.74893 37.02661 -19.87428 1.000 33.45431 ? 258 THR B CB  1 
ATOM   4226 O OG1 . THR B 1 257 ? -43.28995 37.21002 -21.18895 1.000 31.35909 ? 258 THR B OG1 1 
ATOM   4227 C CG2 . THR B 1 257 ? -41.38394 36.35866 -19.98267 1.000 32.74863 ? 258 THR B CG2 1 
ATOM   4228 N N   . GLY B 1 258 ? -46.06093 36.53036 -19.67288 1.000 33.95782 ? 259 GLY B N   1 
ATOM   4229 C CA  . GLY B 1 258 ? -47.29999 37.28040 -19.64402 1.000 35.67524 ? 259 GLY B CA  1 
ATOM   4230 C C   . GLY B 1 258 ? -47.22287 38.64122 -20.29428 1.000 34.97794 ? 259 GLY B C   1 
ATOM   4231 O O   . GLY B 1 258 ? -48.10204 39.47612 -20.06286 1.000 36.18626 ? 259 GLY B O   1 
ATOM   4232 N N   . VAL B 1 259 ? -46.18345 38.90242 -21.07885 1.000 31.63477 ? 260 VAL B N   1 
ATOM   4233 C CA  . VAL B 1 259 ? -46.01676 40.15892 -21.79521 1.000 30.09539 ? 260 VAL B CA  1 
ATOM   4234 C C   . VAL B 1 259 ? -46.23055 39.87569 -23.27369 1.000 32.73261 ? 260 VAL B C   1 
ATOM   4235 O O   . VAL B 1 259 ? -45.66264 38.91922 -23.81709 1.000 31.78826 ? 260 VAL B O   1 
ATOM   4236 C CB  . VAL B 1 259 ? -44.62787 40.77021 -21.54654 1.000 32.89195 ? 260 VAL B CB  1 
ATOM   4237 C CG1 . VAL B 1 259 ? -44.45094 42.05435 -22.35907 1.000 29.42773 ? 260 VAL B CG1 1 
ATOM   4238 C CG2 . VAL B 1 259 ? -44.40258 41.00798 -20.05481 1.000 28.44609 ? 260 VAL B CG2 1 
ATOM   4239 N N   . ALA B 1 260 ? -47.04734 40.69701 -23.92183 1.000 30.95610 ? 261 ALA B N   1 
ATOM   4240 C CA  . ALA B 1 260 ? -47.39819 40.44054 -25.30858 1.000 30.04471 ? 261 ALA B CA  1 
ATOM   4241 C C   . ALA B 1 260 ? -46.34449 41.00616 -26.24008 1.000 26.96563 ? 261 ALA B C   1 
ATOM   4242 O O   . ALA B 1 260 ? -45.68746 42.01209 -25.94103 1.000 28.91124 ? 261 ALA B O   1 
ATOM   4243 C CB  . ALA B 1 260 ? -48.76202 41.04450 -25.65560 1.000 28.34438 ? 261 ALA B CB  1 
ATOM   4244 N N   . ILE B 1 261 ? -46.19591 40.34449 -27.38823 1.000 28.56733 ? 262 ILE B N   1 
ATOM   4245 C CA  . ILE B 1 261 ? -45.29993 40.82371 -28.43743 1.000 28.64131 ? 262 ILE B CA  1 
ATOM   4246 C C   . ILE B 1 261 ? -45.50629 42.31320 -28.69532 1.000 29.42641 ? 262 ILE B C   1 
ATOM   4247 O O   . ILE B 1 261 ? -44.54298 43.08955 -28.79476 1.000 28.76142 ? 262 ILE B O   1 
ATOM   4248 C CB  . ILE B 1 261 ? -45.51950 39.98883 -29.71080 1.000 27.59636 ? 262 ILE B CB  1 
ATOM   4249 C CG1 . ILE B 1 261 ? -45.02513 38.55350 -29.48936 1.000 32.81537 ? 262 ILE B CG1 1 
ATOM   4250 C CG2 . ILE B 1 261 ? -44.86274 40.63532 -30.90689 1.000 30.23374 ? 262 ILE B CG2 1 
ATOM   4251 C CD1 . ILE B 1 261 ? -45.52199 37.58843 -30.56025 1.000 34.01776 ? 262 ILE B CD1 1 
ATOM   4252 N N   . GLU B 1 262 ? -46.76773 42.74146 -28.77842 1.000 29.03461 ? 263 GLU B N   1 
ATOM   4253 C CA  . GLU B 1 262 ? -47.06838 44.11525 -29.16925 1.000 26.96812 ? 263 GLU B CA  1 
ATOM   4254 C C   . GLU B 1 262 ? -46.62296 45.12730 -28.11429 1.000 29.49156 ? 263 GLU B C   1 
ATOM   4255 O O   . GLU B 1 262 ? -46.32849 46.28345 -28.45410 1.000 30.12390 ? 263 GLU B O   1 
ATOM   4256 C CB  . GLU B 1 262 ? -48.56877 44.24464 -29.45266 1.000 32.23973 ? 263 GLU B CB  1 
ATOM   4257 C CG  . GLU B 1 262 ? -49.02065 43.55512 -30.74236 1.000 32.46987 ? 263 GLU B CG  1 
ATOM   4258 C CD  . GLU B 1 262 ? -49.40860 42.08537 -30.54981 1.000 34.95223 ? 263 GLU B CD  1 
ATOM   4259 O OE1 . GLU B 1 262 ? -49.22316 41.52348 -29.44020 1.000 31.76761 ? 263 GLU B OE1 1 
ATOM   4260 O OE2 . GLU B 1 262 ? -49.90699 41.48804 -31.53122 1.000 35.86649 ? 263 GLU B OE2 1 
ATOM   4261 N N   . GLN B 1 263 ? -46.57616 44.72254 -26.83807 1.000 26.35124 ? 264 GLN B N   1 
ATOM   4262 C CA  . GLN B 1 263 ? -45.98507 45.58887 -25.81686 1.000 30.95010 ? 264 GLN B CA  1 
ATOM   4263 C C   . GLN B 1 263 ? -44.49223 45.78135 -26.05526 1.000 30.31558 ? 264 GLN B C   1 
ATOM   4264 O O   . GLN B 1 263 ? -43.96526 46.88496 -25.89096 1.000 26.15816 ? 264 GLN B O   1 
ATOM   4265 C CB  . GLN B 1 263 ? -46.22099 45.01253 -24.42178 1.000 29.75468 ? 264 GLN B CB  1 
ATOM   4266 C CG  . GLN B 1 263 ? -47.68705 44.98974 -23.96867 1.000 31.45972 ? 264 GLN B CG  1 
ATOM   4267 C CD  . GLN B 1 263 ? -47.88468 44.18412 -22.68343 1.000 29.83183 ? 264 GLN B CD  1 
ATOM   4268 O OE1 . GLN B 1 263 ? -48.14433 42.97581 -22.72589 1.000 30.74313 ? 264 GLN B OE1 1 
ATOM   4269 N NE2 . GLN B 1 263 ? -47.75145 44.84898 -21.53740 1.000 27.72817 ? 264 GLN B NE2 1 
ATOM   4270 N N   . LEU B 1 264 ? -43.78999 44.71976 -26.45000 1.000 27.19051 ? 265 LEU B N   1 
ATOM   4271 C CA  . LEU B 1 264 ? -42.36364 44.87563 -26.69258 1.000 27.19602 ? 265 LEU B CA  1 
ATOM   4272 C C   . LEU B 1 264 ? -42.10320 45.62224 -27.99415 1.000 25.66043 ? 265 LEU B C   1 
ATOM   4273 O O   . LEU B 1 264 ? -41.09474 46.32834 -28.10550 1.000 27.73412 ? 265 LEU B O   1 
ATOM   4274 C CB  . LEU B 1 264 ? -41.68360 43.50819 -26.68381 1.000 27.97268 ? 265 LEU B CB  1 
ATOM   4275 C CG  . LEU B 1 264 ? -41.80382 42.70156 -25.38255 1.000 26.70496 ? 265 LEU B CG  1 
ATOM   4276 C CD1 . LEU B 1 264 ? -40.94460 41.45283 -25.45683 1.000 26.86225 ? 265 LEU B CD1 1 
ATOM   4277 C CD2 . LEU B 1 264 ? -41.41529 43.52276 -24.14501 1.000 27.16696 ? 265 LEU B CD2 1 
ATOM   4278 N N   . LEU B 1 265 ? -43.00384 45.50918 -28.97856 1.000 25.14274 ? 266 LEU B N   1 
ATOM   4279 C CA  . LEU B 1 265 ? -42.83562 46.29596 -30.19372 1.000 24.54418 ? 266 LEU B CA  1 
ATOM   4280 C C   . LEU B 1 265 ? -42.94675 47.78431 -29.88637 1.000 28.33586 ? 266 LEU B C   1 
ATOM   4281 O O   . LEU B 1 265 ? -42.18930 48.59810 -30.42730 1.000 25.31862 ? 266 LEU B O   1 
ATOM   4282 C CB  . LEU B 1 265 ? -43.86173 45.87839 -31.24290 1.000 25.47783 ? 266 LEU B CB  1 
ATOM   4283 C CG  . LEU B 1 265 ? -43.65170 44.45166 -31.77692 1.000 27.54390 ? 266 LEU B CG  1 
ATOM   4284 C CD1 . LEU B 1 265 ? -44.70455 44.10308 -32.82653 1.000 27.23849 ? 266 LEU B CD1 1 
ATOM   4285 C CD2 . LEU B 1 265 ? -42.24567 44.30612 -32.34258 1.000 25.06548 ? 266 LEU B CD2 1 
ATOM   4286 N N   . TYR B 1 266 ? -43.87593 48.15322 -29.00426 1.000 25.68952 ? 267 TYR B N   1 
ATOM   4287 C CA  . TYR B 1 266 ? -43.94766 49.53361 -28.53470 1.000 27.94676 ? 267 TYR B CA  1 
ATOM   4288 C C   . TYR B 1 266 ? -42.65847 49.92556 -27.81272 1.000 27.15885 ? 267 TYR B C   1 
ATOM   4289 O O   . TYR B 1 266 ? -42.08197 50.98584 -28.07588 1.000 27.95360 ? 267 TYR B O   1 
ATOM   4290 C CB  . TYR B 1 266 ? -45.16727 49.70990 -27.62336 1.000 27.35498 ? 267 TYR B CB  1 
ATOM   4291 C CG  . TYR B 1 266 ? -45.29684 51.11530 -27.06365 1.000 32.40144 ? 267 TYR B CG  1 
ATOM   4292 C CD1 . TYR B 1 266 ? -44.67262 51.47063 -25.86604 1.000 32.14025 ? 267 TYR B CD1 1 
ATOM   4293 C CD2 . TYR B 1 266 ? -46.03940 52.08415 -27.73439 1.000 30.53572 ? 267 TYR B CD2 1 
ATOM   4294 C CE1 . TYR B 1 266 ? -44.76948 52.76323 -25.35851 1.000 36.90940 ? 267 TYR B CE1 1 
ATOM   4295 C CE2 . TYR B 1 266 ? -46.15523 53.38147 -27.22447 1.000 35.52177 ? 267 TYR B CE2 1 
ATOM   4296 C CZ  . TYR B 1 266 ? -45.51587 53.70951 -26.04173 1.000 37.86826 ? 267 TYR B CZ  1 
ATOM   4297 O OH  . TYR B 1 266 ? -45.62072 54.98686 -25.54578 1.000 36.98368 ? 267 TYR B OH  1 
ATOM   4298 N N   . ALA B 1 267 ? -42.18909 49.06842 -26.90256 1.000 26.53656 ? 268 ALA B N   1 
ATOM   4299 C CA  . ALA B 1 267 ? -40.97148 49.35958 -26.14854 1.000 27.67827 ? 268 ALA B CA  1 
ATOM   4300 C C   . ALA B 1 267 ? -39.77561 49.59025 -27.07187 1.000 32.11869 ? 268 ALA B C   1 
ATOM   4301 O O   . ALA B 1 267 ? -38.97073 50.50147 -26.83606 1.000 30.39591 ? 268 ALA B O   1 
ATOM   4302 C CB  . ALA B 1 267 ? -40.69379 48.22411 -25.16633 1.000 26.02350 ? 268 ALA B CB  1 
ATOM   4303 N N   . ILE B 1 268 ? -39.64896 48.78294 -28.13445 1.000 28.49223 ? 269 ILE B N   1 
ATOM   4304 C CA  . ILE B 1 268 ? -38.52917 48.92452 -29.06969 1.000 28.61088 ? 269 ILE B CA  1 
ATOM   4305 C C   . ILE B 1 268 ? -38.54768 50.29983 -29.72369 1.000 30.94417 ? 269 ILE B C   1 
ATOM   4306 O O   . ILE B 1 268 ? -37.50098 50.93086 -29.92120 1.000 28.60070 ? 269 ILE B O   1 
ATOM   4307 C CB  . ILE B 1 268 ? -38.57923 47.79821 -30.12530 1.000 26.64389 ? 269 ILE B CB  1 
ATOM   4308 C CG1 . ILE B 1 268 ? -38.00276 46.50271 -29.55559 1.000 27.60856 ? 269 ILE B CG1 1 
ATOM   4309 C CG2 . ILE B 1 268 ? -37.84235 48.19700 -31.39860 1.000 28.46355 ? 269 ILE B CG2 1 
ATOM   4310 C CD1 . ILE B 1 268 ? -38.47551 45.24133 -30.30638 1.000 25.18412 ? 269 ILE B CD1 1 
ATOM   4311 N N   . GLN B 1 269 ? -39.73979 50.77833 -30.08148 1.000 27.86796 ? 270 GLN B N   1 
ATOM   4312 C CA  . GLN B 1 269 ? -39.86464 52.10795 -30.66038 1.000 30.56792 ? 270 GLN B CA  1 
ATOM   4313 C C   . GLN B 1 269 ? -39.36106 53.17471 -29.70063 1.000 33.48656 ? 270 GLN B C   1 
ATOM   4314 O O   . GLN B 1 269 ? -38.75842 54.16570 -30.13149 1.000 34.28171 ? 270 GLN B O   1 
ATOM   4315 C CB  . GLN B 1 269 ? -41.31963 52.36953 -31.04783 1.000 30.69969 ? 270 GLN B CB  1 
ATOM   4316 C CG  . GLN B 1 269 ? -41.75449 51.56860 -32.26391 1.000 31.65200 ? 270 GLN B CG  1 
ATOM   4317 C CD  . GLN B 1 269 ? -43.21708 51.76688 -32.60812 1.000 32.56073 ? 270 GLN B CD  1 
ATOM   4318 O OE1 . GLN B 1 269 ? -44.09143 51.63412 -31.75139 1.000 30.42660 ? 270 GLN B OE1 1 
ATOM   4319 N NE2 . GLN B 1 269 ? -43.48749 52.07386 -33.87248 1.000 30.74901 ? 270 GLN B NE2 1 
ATOM   4320 N N   . GLN B 1 270 ? -39.58475 52.98490 -28.39532 1.000 28.86318 ? 271 GLN B N   1 
ATOM   4321 C CA  . GLN B 1 270 ? -39.09911 53.96488 -27.42146 1.000 33.94860 ? 271 GLN B CA  1 
ATOM   4322 C C   . GLN B 1 270 ? -37.60897 53.79900 -27.14738 1.000 34.90466 ? 271 GLN B C   1 
ATOM   4323 O O   . GLN B 1 270 ? -36.87949 54.79127 -27.06371 1.000 34.33960 ? 271 GLN B O   1 
ATOM   4324 C CB  . GLN B 1 270 ? -39.87678 53.86054 -26.10887 1.000 31.59756 ? 271 GLN B CB  1 
ATOM   4325 C CG  . GLN B 1 270 ? -41.38929 53.70714 -26.24696 1.000 33.19581 ? 271 GLN B CG  1 
ATOM   4326 C CD  . GLN B 1 270 ? -42.00872 54.68687 -27.23113 1.000 40.81501 ? 271 GLN B CD  1 
ATOM   4327 O OE1 . GLN B 1 270 ? -41.76020 55.89591 -27.17041 1.000 41.25869 ? 271 GLN B OE1 1 
ATOM   4328 N NE2 . GLN B 1 270 ? -42.82860 54.16606 -28.14993 1.000 37.53424 ? 271 GLN B NE2 1 
ATOM   4329 N N   . LEU B 1 271 ? -37.13844 52.55658 -27.00530 1.000 34.05199 ? 272 LEU B N   1 
ATOM   4330 C CA  . LEU B 1 271 ? -35.72157 52.33157 -26.73396 1.000 32.52284 ? 272 LEU B CA  1 
ATOM   4331 C C   . LEU B 1 271 ? -34.85111 52.77671 -27.89261 1.000 33.85233 ? 272 LEU B C   1 
ATOM   4332 O O   . LEU B 1 271 ? -33.70173 53.17983 -27.68589 1.000 35.77123 ? 272 LEU B O   1 
ATOM   4333 C CB  . LEU B 1 271 ? -35.46966 50.85533 -26.43518 1.000 31.64433 ? 272 LEU B CB  1 
ATOM   4334 C CG  . LEU B 1 271 ? -36.14532 50.36253 -25.16062 1.000 31.35962 ? 272 LEU B CG  1 
ATOM   4335 C CD1 . LEU B 1 271 ? -36.08291 48.86141 -25.07336 1.000 30.02054 ? 272 LEU B CD1 1 
ATOM   4336 C CD2 . LEU B 1 271 ? -35.50017 51.00269 -23.93240 1.000 35.19104 ? 272 LEU B CD2 1 
ATOM   4337 N N   . TYR B 1 272 ? -35.37186 52.69126 -29.11735 1.000 32.79511 ? 273 TYR B N   1 
ATOM   4338 C CA  . TYR B 1 272 ? -34.62100 53.14936 -30.27861 1.000 35.42988 ? 273 TYR B CA  1 
ATOM   4339 C C   . TYR B 1 272 ? -34.26894 54.63248 -30.16471 1.000 39.22905 ? 273 TYR B C   1 
ATOM   4340 O O   . TYR B 1 272 ? -33.16211 55.04448 -30.52906 1.000 39.53175 ? 273 TYR B O   1 
ATOM   4341 C CB  . TYR B 1 272 ? -35.42713 52.88377 -31.54268 1.000 35.92666 ? 273 TYR B CB  1 
ATOM   4342 C CG  . TYR B 1 272 ? -34.71654 53.25970 -32.80985 1.000 39.58834 ? 273 TYR B CG  1 
ATOM   4343 C CD1 . TYR B 1 272 ? -33.54065 52.61233 -33.18767 1.000 41.34853 ? 273 TYR B CD1 1 
ATOM   4344 C CD2 . TYR B 1 272 ? -35.21745 54.25242 -33.63663 1.000 37.77291 ? 273 TYR B CD2 1 
ATOM   4345 C CE1 . TYR B 1 272 ? -32.88407 52.94858 -34.36392 1.000 40.04663 ? 273 TYR B CE1 1 
ATOM   4346 C CE2 . TYR B 1 272 ? -34.57080 54.59670 -34.80716 1.000 41.24841 ? 273 TYR B CE2 1 
ATOM   4347 C CZ  . TYR B 1 272 ? -33.40590 53.94032 -35.16913 1.000 42.06322 ? 273 TYR B CZ  1 
ATOM   4348 O OH  . TYR B 1 272 ? -32.75681 54.28243 -36.33802 1.000 47.33916 ? 273 TYR B OH  1 
ATOM   4349 N N   . THR B 1 273 ? -35.19116 55.45404 -29.65735 1.000 40.47073 ? 274 THR B N   1 
ATOM   4350 C CA  . THR B 1 273 ? -34.85778 56.86341 -29.45504 1.000 41.58469 ? 274 THR B CA  1 
ATOM   4351 C C   . THR B 1 273 ? -33.94251 57.07481 -28.25260 1.000 43.93596 ? 274 THR B C   1 
ATOM   4352 O O   . THR B 1 273 ? -33.29989 58.12665 -28.15193 1.000 47.80199 ? 274 THR B O   1 
ATOM   4353 C CB  . THR B 1 273 ? -36.12733 57.70423 -29.29922 1.000 40.05652 ? 274 THR B CB  1 
ATOM   4354 O OG1 . THR B 1 273 ? -36.85845 57.27611 -28.14366 1.000 47.28077 ? 274 THR B OG1 1 
ATOM   4355 C CG2 . THR B 1 273 ? -37.00701 57.56344 -30.52681 1.000 41.95723 ? 274 THR B CG2 1 
ATOM   4356 N N   . GLY B 1 274 ? -33.86037 56.10122 -27.34908 1.000 41.09647 ? 275 GLY B N   1 
ATOM   4357 C CA  . GLY B 1 274 ? -32.93834 56.18052 -26.23306 1.000 43.29509 ? 275 GLY B CA  1 
ATOM   4358 C C   . GLY B 1 274 ? -33.35842 55.34041 -25.05013 1.000 42.07762 ? 275 GLY B C   1 
ATOM   4359 O O   . GLY B 1 274 ? -34.55411 55.19859 -24.77667 1.000 44.27362 ? 275 GLY B O   1 
ATOM   4360 N N   . PHE B 1 275 ? -32.38298 54.77000 -24.34310 1.000 38.62433 ? 276 PHE B N   1 
ATOM   4361 C CA  . PHE B 1 275 ? -32.66067 54.06637 -23.09828 1.000 40.17751 ? 276 PHE B CA  1 
ATOM   4362 C C   . PHE B 1 275 ? -33.00102 55.02702 -21.97457 1.000 52.52120 ? 276 PHE B C   1 
ATOM   4363 O O   . PHE B 1 275 ? -33.27202 54.58329 -20.84872 1.000 46.06173 ? 276 PHE B O   1 
ATOM   4364 C CB  . PHE B 1 275 ? -31.46172 53.20361 -22.69122 1.000 39.58806 ? 276 PHE B CB  1 
ATOM   4365 C CG  . PHE B 1 275 ? -31.37706 51.88545 -23.42650 1.000 41.34906 ? 276 PHE B CG  1 
ATOM   4366 C CD1 . PHE B 1 275 ? -31.55091 51.82986 -24.79960 1.000 40.70202 ? 276 PHE B CD1 1 
ATOM   4367 C CD2 . PHE B 1 275 ? -31.10316 50.70918 -22.74536 1.000 39.05762 ? 276 PHE B CD2 1 
ATOM   4368 C CE1 . PHE B 1 275 ? -31.46473 50.61474 -25.48258 1.000 38.95622 ? 276 PHE B CE1 1 
ATOM   4369 C CE2 . PHE B 1 275 ? -31.01298 49.49685 -23.41627 1.000 39.48082 ? 276 PHE B CE2 1 
ATOM   4370 C CZ  . PHE B 1 275 ? -31.19653 49.44851 -24.78561 1.000 38.60378 ? 276 PHE B CZ  1 
ATOM   4371 N N   . GLN B 1 276 ? -33.02074 56.32500 -22.28633 1.000 54.74658 ? 277 GLN B N   1 
ATOM   4372 C CA  . GLN B 1 276 ? -33.04239 57.40919 -21.31458 1.000 58.86727 ? 277 GLN B CA  1 
ATOM   4373 C C   . GLN B 1 276 ? -31.91177 57.20492 -20.31392 1.000 60.55089 ? 277 GLN B C   1 
ATOM   4374 O O   . GLN B 1 276 ? -30.74052 57.17682 -20.70945 1.000 61.85193 ? 277 GLN B O   1 
ATOM   4375 C CB  . GLN B 1 276 ? -34.42310 57.51859 -20.66395 1.000 57.70640 ? 277 GLN B CB  1 
ATOM   4376 C CG  . GLN B 1 276 ? -35.58867 57.59023 -21.69418 1.000 62.39544 ? 277 GLN B CG  1 
ATOM   4377 C CD  . GLN B 1 276 ? -35.40706 58.64138 -22.82433 1.000 65.81437 ? 277 GLN B CD  1 
ATOM   4378 O OE1 . GLN B 1 276 ? -34.43224 59.40173 -22.86433 1.000 65.46526 ? 277 GLN B OE1 1 
ATOM   4379 N NE2 . GLN B 1 276 ? -36.36147 58.66369 -23.75464 1.000 65.94883 ? 277 GLN B NE2 1 
ATOM   4380 N N   . GLY B 1 277 ? -32.21860 57.04331 -19.03630 1.000 56.66354 ? 278 GLY B N   1 
ATOM   4381 C CA  . GLY B 1 277 ? -31.11978 56.94875 -18.09706 1.000 57.52975 ? 278 GLY B CA  1 
ATOM   4382 C C   . GLY B 1 277 ? -30.92362 55.58618 -17.47399 1.000 55.10388 ? 278 GLY B C   1 
ATOM   4383 O O   . GLY B 1 277 ? -30.37068 55.48587 -16.37280 1.000 56.65032 ? 278 GLY B O   1 
ATOM   4384 N N   . LYS B 1 278 ? -31.35473 54.53035 -18.16423 1.000 50.39775 ? 279 LYS B N   1 
ATOM   4385 C CA  . LYS B 1 278 ? -31.40593 53.19499 -17.58650 1.000 46.54467 ? 279 LYS B CA  1 
ATOM   4386 C C   . LYS B 1 278 ? -30.64405 52.20520 -18.46482 1.000 44.59530 ? 279 LYS B C   1 
ATOM   4387 O O   . LYS B 1 278 ? -30.16997 52.53632 -19.55630 1.000 42.61962 ? 279 LYS B O   1 
ATOM   4388 C CB  . LYS B 1 278 ? -32.86327 52.75771 -17.39099 1.000 48.25477 ? 279 LYS B CB  1 
ATOM   4389 C CG  . LYS B 1 278 ? -33.71745 53.85167 -16.73826 1.000 51.65095 ? 279 LYS B CG  1 
ATOM   4390 C CD  . LYS B 1 278 ? -35.19597 53.50829 -16.70165 1.000 52.02862 ? 279 LYS B CD  1 
ATOM   4391 C CE  . LYS B 1 278 ? -35.84791 54.06681 -15.44660 1.000 55.25243 ? 279 LYS B CE  1 
ATOM   4392 N NZ  . LYS B 1 278 ? -35.25244 53.48046 -14.20863 1.000 60.66722 ? 279 LYS B NZ  1 
ATOM   4393 N N   . GLN B 1 279 ? -30.52405 50.97358 -17.97057 1.000 41.72493 ? 280 GLN B N   1 
ATOM   4394 C CA  . GLN B 1 279 ? -29.83584 49.90633 -18.68277 1.000 41.36384 ? 280 GLN B CA  1 
ATOM   4395 C C   . GLN B 1 279 ? -30.73316 48.67634 -18.75636 1.000 41.57474 ? 280 GLN B C   1 
ATOM   4396 O O   . GLN B 1 279 ? -31.64770 48.50045 -17.94848 1.000 43.94901 ? 280 GLN B O   1 
ATOM   4397 C CB  . GLN B 1 279 ? -28.50734 49.53851 -18.00353 1.000 44.56102 ? 280 GLN B CB  1 
ATOM   4398 C CG  . GLN B 1 279 ? -27.61550 50.72972 -17.67293 1.000 50.12178 ? 280 GLN B CG  1 
ATOM   4399 C CD  . GLN B 1 279 ? -26.43536 50.33684 -16.80160 1.000 61.29343 ? 280 GLN B CD  1 
ATOM   4400 O OE1 . GLN B 1 279 ? -25.59403 49.53159 -17.20477 1.000 62.49944 ? 280 GLN B OE1 1 
ATOM   4401 N NE2 . GLN B 1 279 ? -26.37010 50.90037 -15.59841 1.000 64.81803 ? 280 GLN B NE2 1 
ATOM   4402 N N   . ILE B 1 280 ? -30.46105 47.81610 -19.73506 1.000 35.33440 ? 281 ILE B N   1 
ATOM   4403 C CA  . ILE B 1 280 ? -31.15315 46.53967 -19.87987 1.000 38.62192 ? 281 ILE B CA  1 
ATOM   4404 C C   . ILE B 1 280 ? -30.09538 45.45583 -19.88091 1.000 37.66366 ? 281 ILE B C   1 
ATOM   4405 O O   . ILE B 1 280 ? -29.25674 45.41183 -20.78748 1.000 38.07846 ? 281 ILE B O   1 
ATOM   4406 C CB  . ILE B 1 280 ? -31.99670 46.47726 -21.16363 1.000 38.75366 ? 281 ILE B CB  1 
ATOM   4407 C CG1 . ILE B 1 280 ? -33.10215 47.52971 -21.12804 1.000 34.58822 ? 281 ILE B CG1 1 
ATOM   4408 C CG2 . ILE B 1 280 ? -32.57113 45.08069 -21.34167 1.000 34.42758 ? 281 ILE B CG2 1 
ATOM   4409 C CD1 . ILE B 1 280 ? -33.86382 47.63115 -22.41845 1.000 34.37384 ? 281 ILE B CD1 1 
ATOM   4410 N N   . LEU B 1 281 ? -30.13189 44.58903 -18.86968 1.000 41.53560 ? 282 LEU B N   1 
ATOM   4411 C CA  . LEU B 1 281 ? -29.10049 43.57350 -18.65558 1.000 40.98249 ? 282 LEU B CA  1 
ATOM   4412 C C   . LEU B 1 281 ? -27.70418 44.19084 -18.73967 1.000 44.48656 ? 282 LEU B C   1 
ATOM   4413 O O   . LEU B 1 281 ? -26.79792 43.66749 -19.39214 1.000 44.24085 ? 282 LEU B O   1 
ATOM   4414 C CB  . LEU B 1 281 ? -29.25760 42.41031 -19.63680 1.000 38.49106 ? 282 LEU B CB  1 
ATOM   4415 C CG  . LEU B 1 281 ? -30.67397 41.83406 -19.69181 1.000 38.99658 ? 282 LEU B CG  1 
ATOM   4416 C CD1 . LEU B 1 281 ? -30.82543 40.74791 -20.75650 1.000 32.77223 ? 282 LEU B CD1 1 
ATOM   4417 C CD2 . LEU B 1 281 ? -31.06663 41.31702 -18.32082 1.000 42.23859 ? 282 LEU B CD2 1 
ATOM   4418 N N   . GLY B 1 282 ? -27.55031 45.33803 -18.07860 1.000 42.90075 ? 283 GLY B N   1 
ATOM   4419 C CA  . GLY B 1 282 ? -26.28879 46.03740 -17.99588 1.000 47.11367 ? 283 GLY B CA  1 
ATOM   4420 C C   . GLY B 1 282 ? -25.86542 46.78041 -19.24277 1.000 46.86093 ? 283 GLY B C   1 
ATOM   4421 O O   . GLY B 1 282 ? -24.82108 47.44772 -19.21605 1.000 54.29430 ? 283 GLY B O   1 
ATOM   4422 N N   . SER B 1 283 ? -26.63803 46.70153 -20.32506 1.000 49.50430 ? 284 SER B N   1 
ATOM   4423 C CA  . SER B 1 283 ? -26.27355 47.28792 -21.60604 1.000 42.57574 ? 284 SER B CA  1 
ATOM   4424 C C   . SER B 1 283 ? -27.17283 48.47721 -21.94376 1.000 37.43386 ? 284 SER B C   1 
ATOM   4425 O O   . SER B 1 283 ? -28.33462 48.54399 -21.52916 1.000 37.68824 ? 284 SER B O   1 
ATOM   4426 C CB  . SER B 1 283 ? -26.35187 46.23404 -22.71434 1.000 38.55232 ? 284 SER B CB  1 
ATOM   4427 O OG  . SER B 1 283 ? -26.06748 46.81423 -23.96604 1.000 39.25980 ? 284 SER B OG  1 
ATOM   4428 N N   . THR B 1 284 ? -26.62093 49.43557 -22.68745 1.000 35.90172 ? 285 THR B N   1 
ATOM   4429 C CA  . THR B 1 284 ? -27.39444 50.58123 -23.14998 1.000 37.51423 ? 285 THR B CA  1 
ATOM   4430 C C   . THR B 1 284 ? -27.60634 50.56277 -24.65697 1.000 36.72832 ? 285 THR B C   1 
ATOM   4431 O O   . THR B 1 284 ? -27.91964 51.59785 -25.24799 1.000 37.70392 ? 285 THR B O   1 
ATOM   4432 C CB  . THR B 1 284 ? -26.73029 51.89204 -22.72652 1.000 42.30864 ? 285 THR B CB  1 
ATOM   4433 O OG1 . THR B 1 284 ? -25.40930 51.96298 -23.27708 1.000 41.34915 ? 285 THR B OG1 1 
ATOM   4434 C CG2 . THR B 1 284 ? -26.65166 51.98777 -21.19756 1.000 41.23321 ? 285 THR B CG2 1 
ATOM   4435 N N   . MET B 1 285 ? -27.43480 49.40796 -25.29304 1.000 37.91343 ? 286 MET B N   1 
ATOM   4436 C CA  . MET B 1 285 ? -27.73099 49.26086 -26.70930 1.000 37.68125 ? 286 MET B CA  1 
ATOM   4437 C C   . MET B 1 285 ? -28.54137 47.99427 -26.92506 1.000 36.37154 ? 286 MET B C   1 
ATOM   4438 O O   . MET B 1 285 ? -28.55424 47.08813 -26.08215 1.000 32.35037 ? 286 MET B O   1 
ATOM   4439 C CB  . MET B 1 285 ? -26.45431 49.22585 -27.57084 1.000 35.29165 ? 286 MET B CB  1 
ATOM   4440 C CG  . MET B 1 285 ? -25.30511 48.41816 -26.99556 1.000 50.20979 ? 286 MET B CG  1 
ATOM   4441 S SD  . MET B 1 285 ? -23.80494 48.59336 -27.99232 1.000 65.27937 ? 286 MET B SD  1 
ATOM   4442 C CE  . MET B 1 285 ? -24.04630 50.22072 -28.73184 1.000 51.17711 ? 286 MET B CE  1 
ATOM   4443 N N   . LEU B 1 286 ? -29.23148 47.95424 -28.05820 1.000 31.44595 ? 287 LEU B N   1 
ATOM   4444 C CA  . LEU B 1 286 ? -30.10213 46.83317 -28.35827 1.000 35.59368 ? 287 LEU B CA  1 
ATOM   4445 C C   . LEU B 1 286 ? -29.27450 45.63992 -28.80947 1.000 30.72572 ? 287 LEU B C   1 
ATOM   4446 O O   . LEU B 1 286 ? -28.30640 45.78854 -29.55838 1.000 33.41303 ? 287 LEU B O   1 
ATOM   4447 C CB  . LEU B 1 286 ? -31.09350 47.21827 -29.44977 1.000 36.06141 ? 287 LEU B CB  1 
ATOM   4448 C CG  . LEU B 1 286 ? -32.08309 48.34500 -29.16095 1.000 35.81307 ? 287 LEU B CG  1 
ATOM   4449 C CD1 . LEU B 1 286 ? -32.81912 48.70724 -30.44573 1.000 32.98734 ? 287 LEU B CD1 1 
ATOM   4450 C CD2 . LEU B 1 286 ? -33.06127 47.91843 -28.07782 1.000 34.37152 ? 287 LEU B CD2 1 
ATOM   4451 N N   . GLU B 1 287 ? -29.66050 44.45215 -28.35858 1.000 29.04205 ? 288 GLU B N   1 
ATOM   4452 C CA  . GLU B 1 287 ? -28.98297 43.21355 -28.72172 1.000 29.20833 ? 288 GLU B CA  1 
ATOM   4453 C C   . GLU B 1 287 ? -29.87259 42.42546 -29.67629 1.000 28.70674 ? 288 GLU B C   1 
ATOM   4454 O O   . GLU B 1 287 ? -31.01423 42.10300 -29.32870 1.000 23.65622 ? 288 GLU B O   1 
ATOM   4455 C CB  . GLU B 1 287 ? -28.68233 42.38760 -27.47419 1.000 31.18757 ? 288 GLU B CB  1 
ATOM   4456 C CG  . GLU B 1 287 ? -28.23551 40.96287 -27.77563 1.000 29.70142 ? 288 GLU B CG  1 
ATOM   4457 C CD  . GLU B 1 287 ? -26.83469 40.94100 -28.35117 1.000 32.87687 ? 288 GLU B CD  1 
ATOM   4458 O OE1 . GLU B 1 287 ? -26.67909 40.64345 -29.54864 1.000 32.71848 ? 288 GLU B OE1 1 
ATOM   4459 O OE2 . GLU B 1 287 ? -25.88951 41.26331 -27.60774 1.000 36.00153 ? 288 GLU B OE2 1 
ATOM   4460 N N   . ASP B 1 288 ? -29.35965 42.10761 -30.87066 1.000 24.36838 ? 289 ASP B N   1 
ATOM   4461 C CA  . ASP B 1 288 ? -30.14520 41.31902 -31.82104 1.000 27.06800 ? 289 ASP B CA  1 
ATOM   4462 C C   . ASP B 1 288 ? -29.44038 40.04197 -32.29156 1.000 28.35402 ? 289 ASP B C   1 
ATOM   4463 O O   . ASP B 1 288 ? -29.80393 39.49089 -33.33337 1.000 27.24218 ? 289 ASP B O   1 
ATOM   4464 C CB  . ASP B 1 288 ? -30.56327 42.17010 -33.02355 1.000 26.51823 ? 289 ASP B CB  1 
ATOM   4465 C CG  . ASP B 1 288 ? -29.41910 42.45234 -34.00051 1.000 30.48177 ? 289 ASP B CG  1 
ATOM   4466 O OD1 . ASP B 1 288 ? -28.23968 42.17404 -33.69814 1.000 28.61764 ? 289 ASP B OD1 1 
ATOM   4467 O OD2 . ASP B 1 288 ? -29.71627 42.97882 -35.09545 1.000 26.64434 ? 289 ASP B OD2 1 
ATOM   4468 N N   . GLU B 1 289 ? -28.46024 39.54017 -31.54746 1.000 28.13657 ? 290 GLU B N   1 
ATOM   4469 C CA  . GLU B 1 289 ? -27.72944 38.35704 -31.97863 1.000 26.96282 ? 290 GLU B CA  1 
ATOM   4470 C C   . GLU B 1 289 ? -28.19678 37.07731 -31.29571 1.000 26.91001 ? 290 GLU B C   1 
ATOM   4471 O O   . GLU B 1 289 ? -27.63403 36.01355 -31.56785 1.000 28.67086 ? 290 GLU B O   1 
ATOM   4472 C CB  . GLU B 1 289 ? -26.22722 38.56490 -31.75887 1.000 30.06359 ? 290 GLU B CB  1 
ATOM   4473 C CG  . GLU B 1 289 ? -25.68910 39.78593 -32.50862 1.000 33.54294 ? 290 GLU B CG  1 
ATOM   4474 C CD  . GLU B 1 289 ? -24.16723 39.94675 -32.43659 1.000 41.25298 ? 290 GLU B CD  1 
ATOM   4475 O OE1 . GLU B 1 289 ? -23.62347 40.77083 -33.21903 1.000 41.28882 ? 290 GLU B OE1 1 
ATOM   4476 O OE2 . GLU B 1 289 ? -23.51975 39.27360 -31.59705 1.000 35.40568 ? 290 GLU B OE2 1 
ATOM   4477 N N   . PHE B 1 290 ? -29.22512 37.13678 -30.44819 1.000 23.66639 ? 291 PHE B N   1 
ATOM   4478 C CA  . PHE B 1 290 ? -29.81158 35.93905 -29.85251 1.000 27.18298 ? 291 PHE B CA  1 
ATOM   4479 C C   . PHE B 1 290 ? -31.24882 35.75617 -30.31785 1.000 26.12209 ? 291 PHE B C   1 
ATOM   4480 O O   . PHE B 1 290 ? -32.02783 36.71447 -30.36688 1.000 28.55732 ? 291 PHE B O   1 
ATOM   4481 C CB  . PHE B 1 290 ? -29.77169 35.98449 -28.32403 1.000 24.97439 ? 291 PHE B CB  1 
ATOM   4482 C CG  . PHE B 1 290 ? -28.39032 35.99801 -27.77215 1.000 28.87533 ? 291 PHE B CG  1 
ATOM   4483 C CD1 . PHE B 1 290 ? -27.66323 34.82365 -27.66708 1.000 29.55033 ? 291 PHE B CD1 1 
ATOM   4484 C CD2 . PHE B 1 290 ? -27.80347 37.19350 -27.37547 1.000 31.91624 ? 291 PHE B CD2 1 
ATOM   4485 C CE1 . PHE B 1 290 ? -26.37661 34.83237 -27.15453 1.000 31.92715 ? 291 PHE B CE1 1 
ATOM   4486 C CE2 . PHE B 1 290 ? -26.51157 37.21595 -26.86652 1.000 32.90507 ? 291 PHE B CE2 1 
ATOM   4487 C CZ  . PHE B 1 290 ? -25.79871 36.03773 -26.75848 1.000 31.99779 ? 291 PHE B CZ  1 
ATOM   4488 N N   . THR B 1 291 ? -31.59499 34.52602 -30.64828 1.000 23.98571 ? 292 THR B N   1 
ATOM   4489 C CA  . THR B 1 291 ? -32.88166 34.21189 -31.23927 1.000 25.48667 ? 292 THR B CA  1 
ATOM   4490 C C   . THR B 1 291 ? -33.88201 33.83684 -30.16341 1.000 24.09605 ? 292 THR B C   1 
ATOM   4491 O O   . THR B 1 291 ? -33.50544 33.51980 -29.03367 1.000 24.92009 ? 292 THR B O   1 
ATOM   4492 C CB  . THR B 1 291 ? -32.74501 33.04962 -32.22950 1.000 24.34459 ? 292 THR B CB  1 
ATOM   4493 O OG1 . THR B 1 291 ? -32.43710 31.85901 -31.50755 1.000 26.62195 ? 292 THR B OG1 1 
ATOM   4494 C CG2 . THR B 1 291 ? -31.66406 33.32063 -33.26896 1.000 26.16633 ? 292 THR B CG2 1 
ATOM   4495 N N   . PRO B 1 292 ? -35.17501 33.86229 -30.49219 1.000 25.66555 ? 293 PRO B N   1 
ATOM   4496 C CA  . PRO B 1 292 ? -36.16887 33.25790 -29.59125 1.000 25.12157 ? 293 PRO B CA  1 
ATOM   4497 C C   . PRO B 1 292 ? -35.81970 31.83869 -29.16388 1.000 27.83061 ? 293 PRO B C   1 
ATOM   4498 O O   . PRO B 1 292 ? -36.04922 31.48138 -28.00469 1.000 26.77977 ? 293 PRO B O   1 
ATOM   4499 C CB  . PRO B 1 292 ? -37.45811 33.28167 -30.42646 1.000 24.91754 ? 293 PRO B CB  1 
ATOM   4500 C CG  . PRO B 1 292 ? -37.25000 34.35632 -31.43039 1.000 26.47642 ? 293 PRO B CG  1 
ATOM   4501 C CD  . PRO B 1 292 ? -35.78722 34.41372 -31.71599 1.000 25.25333 ? 293 PRO B CD  1 
ATOM   4502 N N   . GLU B 1 293 ? -35.29705 31.01257 -30.07760 1.000 26.30817 ? 294 GLU B N   1 
ATOM   4503 C CA  . GLU B 1 293 ? -34.91421 29.64573 -29.71621 1.000 27.88002 ? 294 GLU B CA  1 
ATOM   4504 C C   . GLU B 1 293 ? -33.78848 29.64077 -28.68268 1.000 29.27026 ? 294 GLU B C   1 
ATOM   4505 O O   . GLU B 1 293 ? -33.80194 28.83122 -27.74719 1.000 27.39565 ? 294 GLU B O   1 
ATOM   4506 C CB  . GLU B 1 293 ? -34.48934 28.86679 -30.96245 1.000 26.19321 ? 294 GLU B CB  1 
ATOM   4507 C CG  . GLU B 1 293 ? -35.60836 28.59399 -31.97082 1.000 31.71274 ? 294 GLU B CG  1 
ATOM   4508 C CD  . GLU B 1 293 ? -35.93288 29.79644 -32.88080 1.000 32.28077 ? 294 GLU B CD  1 
ATOM   4509 O OE1 . GLU B 1 293 ? -35.19771 30.81683 -32.85885 1.000 30.47879 ? 294 GLU B OE1 1 
ATOM   4510 O OE2 . GLU B 1 293 ? -36.93292 29.71263 -33.62539 1.000 33.98272 ? 294 GLU B OE2 1 
ATOM   4511 N N   . ASP B 1 294 ? -32.79499 30.52655 -28.85415 1.000 26.10329 ? 295 ASP B N   1 
ATOM   4512 C CA  . ASP B 1 294 ? -31.70815 30.65789 -27.88336 1.000 25.34058 ? 295 ASP B CA  1 
ATOM   4513 C C   . ASP B 1 294 ? -32.25675 30.91986 -26.48574 1.000 30.08580 ? 295 ASP B C   1 
ATOM   4514 O O   . ASP B 1 294 ? -31.89608 30.23806 -25.51873 1.000 29.26264 ? 295 ASP B O   1 
ATOM   4515 C CB  . ASP B 1 294 ? -30.77611 31.80647 -28.28336 1.000 28.73932 ? 295 ASP B CB  1 
ATOM   4516 C CG  . ASP B 1 294 ? -29.93351 31.49377 -29.49700 1.000 30.47176 ? 295 ASP B CG  1 
ATOM   4517 O OD1 . ASP B 1 294 ? -29.73757 30.29911 -29.78530 1.000 31.63869 ? 295 ASP B OD1 1 
ATOM   4518 O OD2 . ASP B 1 294 ? -29.46996 32.45838 -30.15708 1.000 28.52065 ? 295 ASP B OD2 1 
ATOM   4519 N N   . VAL B 1 295 ? -33.13632 31.91676 -26.36608 1.000 27.01685 ? 296 VAL B N   1 
ATOM   4520 C CA  . VAL B 1 295 ? -33.69123 32.27270 -25.06337 1.000 29.92498 ? 296 VAL B CA  1 
ATOM   4521 C C   . VAL B 1 295 ? -34.49432 31.11243 -24.48729 1.000 29.67882 ? 296 VAL B C   1 
ATOM   4522 O O   . VAL B 1 295 ? -34.37389 30.78881 -23.30130 1.000 31.83627 ? 296 VAL B O   1 
ATOM   4523 C CB  . VAL B 1 295 ? -34.53513 33.55777 -25.17914 1.000 26.89431 ? 296 VAL B CB  1 
ATOM   4524 C CG1 . VAL B 1 295 ? -35.19301 33.88692 -23.84212 1.000 28.70708 ? 296 VAL B CG1 1 
ATOM   4525 C CG2 . VAL B 1 295 ? -33.66750 34.73110 -25.66665 1.000 25.94382 ? 296 VAL B CG2 1 
ATOM   4526 N N   . ASN B 1 296 ? -35.31039 30.45492 -25.31820 1.000 28.83969 ? 297 ASN B N   1 
ATOM   4527 C CA  . ASN B 1 296 ? -36.11096 29.33496 -24.82581 1.000 32.19621 ? 297 ASN B CA  1 
ATOM   4528 C C   . ASN B 1 296 ? -35.23865 28.20712 -24.29274 1.000 34.28456 ? 297 ASN B C   1 
ATOM   4529 O O   . ASN B 1 296 ? -35.54787 27.62061 -23.25102 1.000 31.71055 ? 297 ASN B O   1 
ATOM   4530 C CB  . ASN B 1 296 ? -37.02543 28.79784 -25.92299 1.000 30.31826 ? 297 ASN B CB  1 
ATOM   4531 C CG  . ASN B 1 296 ? -38.36266 29.51147 -25.96448 1.000 35.31213 ? 297 ASN B CG  1 
ATOM   4532 O OD1 . ASN B 1 296 ? -39.08763 29.57104 -24.96097 1.000 34.49253 ? 297 ASN B OD1 1 
ATOM   4533 N ND2 . ASN B 1 296 ? -38.69044 30.07725 -27.12506 1.000 32.40292 ? 297 ASN B ND2 1 
ATOM   4534 N N   . MET B 1 297 ? -34.15786 27.86505 -24.99567 1.000 32.17347 ? 298 MET B N   1 
ATOM   4535 C CA  . MET B 1 297 ? -33.38243 26.71962 -24.53323 1.000 32.97500 ? 298 MET B CA  1 
ATOM   4536 C C   . MET B 1 297 ? -32.39962 27.08093 -23.41974 1.000 33.79777 ? 298 MET B C   1 
ATOM   4537 O O   . MET B 1 297 ? -32.03059 26.20084 -22.63611 1.000 33.88370 ? 298 MET B O   1 
ATOM   4538 C CB  . MET B 1 297 ? -32.66457 26.03900 -25.71047 1.000 37.79541 ? 298 MET B CB  1 
ATOM   4539 C CG  . MET B 1 297 ? -31.76050 26.91953 -26.54931 1.000 38.86718 ? 298 MET B CG  1 
ATOM   4540 S SD  . MET B 1 297 ? -30.72880 25.96998 -27.70823 1.000 54.57861 ? 298 MET B SD  1 
ATOM   4541 C CE  . MET B 1 297 ? -31.97501 24.93631 -28.49448 1.000 44.14800 ? 298 MET B CE  1 
ATOM   4542 N N   . GLN B 1 298 ? -32.02415 28.35467 -23.27645 1.000 31.45143 ? 299 GLN B N   1 
ATOM   4543 C CA  . GLN B 1 298 ? -31.02802 28.73851 -22.28081 1.000 30.82399 ? 299 GLN B CA  1 
ATOM   4544 C C   . GLN B 1 298 ? -31.62617 29.25882 -20.97874 1.000 35.38195 ? 299 GLN B C   1 
ATOM   4545 O O   . GLN B 1 298 ? -30.98291 29.14064 -19.92886 1.000 32.57429 ? 299 GLN B O   1 
ATOM   4546 C CB  . GLN B 1 298 ? -30.07979 29.79713 -22.86064 1.000 28.01140 ? 299 GLN B CB  1 
ATOM   4547 C CG  . GLN B 1 298 ? -29.13907 29.25538 -23.92743 1.000 28.80949 ? 299 GLN B CG  1 
ATOM   4548 C CD  . GLN B 1 298 ? -28.05845 30.25114 -24.31213 1.000 30.37783 ? 299 GLN B CD  1 
ATOM   4549 O OE1 . GLN B 1 298 ? -27.62128 31.04594 -23.48558 1.000 28.66479 ? 299 GLN B OE1 1 
ATOM   4550 N NE2 . GLN B 1 298 ? -27.61658 30.20612 -25.57213 1.000 27.69158 ? 299 GLN B NE2 1 
ATOM   4551 N N   . ILE B 1 299 ? -32.83392 29.81920 -21.00500 1.000 36.43747 ? 300 ILE B N   1 
ATOM   4552 C CA  . ILE B 1 299 ? -33.42490 30.40603 -19.79839 1.000 39.25614 ? 300 ILE B CA  1 
ATOM   4553 C C   . ILE B 1 299 ? -34.59966 29.59091 -19.24918 1.000 42.23206 ? 300 ILE B C   1 
ATOM   4554 O O   . ILE B 1 299 ? -35.45282 29.10538 -20.00006 1.000 43.85368 ? 300 ILE B O   1 
ATOM   4555 C CB  . ILE B 1 299 ? -33.86720 31.84663 -20.06063 1.000 40.40202 ? 300 ILE B CB  1 
ATOM   4556 C CG1 . ILE B 1 299 ? -32.71280 32.66143 -20.64052 1.000 39.30306 ? 300 ILE B CG1 1 
ATOM   4557 C CG2 . ILE B 1 299 ? -34.35535 32.49188 -18.78153 1.000 43.98576 ? 300 ILE B CG2 1 
ATOM   4558 C CD1 . ILE B 1 299 ? -31.42520 32.56014 -19.85059 1.000 41.63565 ? 300 ILE B CD1 1 
HETATM 4559 C C02 . X77 C 2 .   ? -27.48742 18.20274 -11.78494 1.000 27.35389 ? 401 X77 A C02 1 
HETATM 4560 C C04 . X77 C 2 .   ? -27.59624 20.51190 -10.68707 1.000 26.75617 ? 401 X77 A C04 1 
HETATM 4561 C C05 . X77 C 2 .   ? -27.04477 21.24402 -9.47191  1.000 32.22474 ? 401 X77 A C05 1 
HETATM 4562 C C07 . X77 C 2 .   ? -27.53814 22.39072 -7.30006  1.000 36.99753 ? 401 X77 A C07 1 
HETATM 4563 C C08 . X77 C 2 .   ? -28.65225 23.32235 -6.82602  1.000 39.09834 ? 401 X77 A C08 1 
HETATM 4564 C C09 . X77 C 2 .   ? -28.57205 23.58934 -5.32811  1.000 44.68979 ? 401 X77 A C09 1 
HETATM 4565 C C10 . X77 C 2 .   ? -27.15745 23.39198 -4.77682  1.000 46.22441 ? 401 X77 A C10 1 
HETATM 4566 C C11 . X77 C 2 .   ? -26.70331 21.93964 -4.91623  1.000 47.91731 ? 401 X77 A C11 1 
HETATM 4567 C C12 . X77 C 2 .   ? -27.07198 21.34722 -6.28053  1.000 38.91027 ? 401 X77 A C12 1 
HETATM 4568 C C14 . X77 C 2 .   ? -27.13411 21.31397 -11.89711 1.000 26.60734 ? 401 X77 A C14 1 
HETATM 4569 C C15 . X77 C 2 .   ? -28.15110 22.12280 -12.63313 1.000 26.96123 ? 401 X77 A C15 1 
HETATM 4570 C C16 . X77 C 2 .   ? -27.72300 22.95368 -13.80232 1.000 31.21188 ? 401 X77 A C16 1 
HETATM 4571 C C17 . X77 C 2 .   ? -26.25918 22.95941 -14.21485 1.000 29.60828 ? 401 X77 A C17 1 
HETATM 4572 C C19 . X77 C 2 .   ? -25.66235 21.31513 -12.30729 1.000 29.57829 ? 401 X77 A C19 1 
HETATM 4573 C C20 . X77 C 2 .   ? -26.57865 18.61789 -9.42193  1.000 29.36669 ? 401 X77 A C20 1 
HETATM 4574 C C21 . X77 C 2 .   ? -27.59810 18.14590 -8.38973  1.000 31.16282 ? 401 X77 A C21 1 
HETATM 4575 C C22 . X77 C 2 .   ? -27.12185 17.60025 -7.04228  1.000 29.85373 ? 401 X77 A C22 1 
HETATM 4576 C C23 . X77 C 2 .   ? -25.61922 17.55231 -6.75814  1.000 30.13151 ? 401 X77 A C23 1 
HETATM 4577 C C24 . X77 C 2 .   ? -25.20815 16.97043 -5.39272  1.000 33.41827 ? 401 X77 A C24 1 
HETATM 4578 C C25 . X77 C 2 .   ? -25.93573 17.69516 -4.26917  1.000 35.34190 ? 401 X77 A C25 1 
HETATM 4579 C C26 . X77 C 2 .   ? -23.71601 17.04401 -5.19269  1.000 29.37944 ? 401 X77 A C26 1 
HETATM 4580 C C27 . X77 C 2 .   ? -25.63606 15.48676 -5.44889  1.000 30.88246 ? 401 X77 A C27 1 
HETATM 4581 C C28 . X77 C 2 .   ? -24.59119 18.01387 -7.79391  1.000 30.00817 ? 401 X77 A C28 1 
HETATM 4582 C C29 . X77 C 2 .   ? -25.06066 18.56485 -9.16140  1.000 32.10846 ? 401 X77 A C29 1 
HETATM 4583 C C30 . X77 C 2 .   ? -27.12163 16.71357 -11.75369 1.000 32.45783 ? 401 X77 A C30 1 
HETATM 4584 C C31 . X77 C 2 .   ? -27.40063 15.83050 -12.76663 1.000 31.56495 ? 401 X77 A C31 1 
HETATM 4585 C C33 . X77 C 2 .   ? -26.43499 14.76548 -11.17151 1.000 28.78261 ? 401 X77 A C33 1 
HETATM 4586 N N03 . X77 C 2 .   ? -27.18559 19.11002 -10.66067 1.000 29.18189 ? 401 X77 A N03 1 
HETATM 4587 N N06 . X77 C 2 .   ? -28.02599 21.67151 -8.47914  1.000 30.30371 ? 401 X77 A N06 1 
HETATM 4588 N N18 . X77 C 2 .   ? -25.26683 22.15059 -13.47215 1.000 25.44563 ? 401 X77 A N18 1 
HETATM 4589 N N32 . X77 C 2 .   ? -26.96846 14.64669 -12.40077 1.000 34.36908 ? 401 X77 A N32 1 
HETATM 4590 N N34 . X77 C 2 .   ? -26.53572 16.05306 -10.78412 1.000 32.48795 ? 401 X77 A N34 1 
HETATM 4591 O O01 . X77 C 2 .   ? -28.04045 18.63194 -12.73579 1.000 30.14997 ? 401 X77 A O01 1 
HETATM 4592 O O13 . X77 C 2 .   ? -25.88091 21.49109 -9.32453  1.000 28.39258 ? 401 X77 A O13 1 
HETATM 4593 C C02 . X77 D 2 .   ? -9.51738  33.72641 -49.74389 1.000 33.05387 ? 401 X77 B C02 1 
HETATM 4594 C C04 . X77 D 2 .   ? -10.22065 36.13730 -49.30127 1.000 36.45458 ? 401 X77 B C04 1 
HETATM 4595 C C05 . X77 D 2 .   ? -11.15131 37.19186 -49.87581 1.000 33.73427 ? 401 X77 B C05 1 
HETATM 4596 C C07 . X77 D 2 .   ? -11.43300 39.39296 -51.04265 1.000 42.91391 ? 401 X77 B C07 1 
HETATM 4597 C C08 . X77 D 2 .   ? -10.63584 40.69896 -51.06178 1.000 42.07210 ? 401 X77 B C08 1 
HETATM 4598 C C09 . X77 D 2 .   ? -11.21618 41.76601 -51.99308 1.000 48.40003 ? 401 X77 B C09 1 
HETATM 4599 C C10 . X77 D 2 .   ? -12.47790 41.30859 -52.73041 1.000 49.91658 ? 401 X77 B C10 1 
HETATM 4600 C C11 . X77 D 2 .   ? -12.24689 39.96752 -53.41430 1.000 46.02311 ? 401 X77 B C11 1 
HETATM 4601 C C12 . X77 D 2 .   ? -11.91610 38.86435 -52.40119 1.000 44.10699 ? 401 X77 B C12 1 
HETATM 4602 C C14 . X77 D 2 .   ? -10.75442 35.85100 -47.90535 1.000 31.72105 ? 401 X77 B C14 1 
HETATM 4603 C C15 . X77 D 2 .   ? -9.96132  36.33884 -46.74839 1.000 33.10234 ? 401 X77 B C15 1 
HETATM 4604 C C16 . X77 D 2 .   ? -10.46025 36.09501 -45.37280 1.000 34.45353 ? 401 X77 B C16 1 
HETATM 4605 C C17 . X77 D 2 .   ? -11.77830 35.36477 -45.17877 1.000 28.04220 ? 401 X77 B C17 1 
HETATM 4606 C C19 . X77 D 2 .   ? -12.08011 35.12429 -47.72694 1.000 31.11808 ? 401 X77 B C19 1 
HETATM 4607 C C20 . X77 D 2 .   ? -10.80575 35.08123 -51.50986 1.000 35.13514 ? 401 X77 B C20 1 
HETATM 4608 C C21 . X77 D 2 .   ? -9.88506  35.65359 -52.57507 1.000 34.30291 ? 401 X77 B C21 1 
HETATM 4609 C C22 . X77 D 2 .   ? -10.41901 35.82812 -53.99674 1.000 35.48431 ? 401 X77 B C22 1 
HETATM 4610 C C23 . X77 D 2 .   ? -11.86830 35.43018 -54.30809 1.000 33.96011 ? 401 X77 B C23 1 
HETATM 4611 C C24 . X77 D 2 .   ? -12.33642 35.62514 -55.75107 1.000 41.79837 ? 401 X77 B C24 1 
HETATM 4612 C C25 . X77 D 2 .   ? -11.99097 37.05141 -56.15955 1.000 48.14252 ? 401 X77 B C25 1 
HETATM 4613 C C26 . X77 D 2 .   ? -13.82654 35.39954 -55.86835 1.000 36.51935 ? 401 X77 B C26 1 
HETATM 4614 C C27 . X77 D 2 .   ? -11.54749 34.59836 -56.60196 1.000 42.25836 ? 401 X77 B C27 1 
HETATM 4615 C C28 . X77 D 2 .   ? -12.79944 34.85385 -53.24444 1.000 35.04856 ? 401 X77 B C28 1 
HETATM 4616 C C29 . X77 D 2 .   ? -12.25844 34.67813 -51.81298 1.000 32.80032 ? 401 X77 B C29 1 
HETATM 4617 C C30 . X77 D 2 .   ? -9.44124  32.47211 -50.63272 1.000 34.29433 ? 401 X77 B C30 1 
HETATM 4618 C C31 . X77 D 2 .   ? -8.75966  31.33960 -50.29677 1.000 31.67951 ? 401 X77 B C31 1 
HETATM 4619 C C33 . X77 D 2 .   ? -9.66398  31.04907 -52.22943 1.000 34.64661 ? 401 X77 B C33 1 
HETATM 4620 N N03 . X77 D 2 .   ? -10.20388 34.95695 -50.17181 1.000 32.87910 ? 401 X77 B N03 1 
HETATM 4621 N N06 . X77 D 2 .   ? -10.54476 38.37242 -50.48521 1.000 38.22264 ? 401 X77 B N06 1 
HETATM 4622 N N18 . X77 D 2 .   ? -12.56025 34.90031 -46.34328 1.000 29.04762 ? 401 X77 B N18 1 
HETATM 4623 N N32 . X77 D 2 .   ? -8.90553  30.48024 -51.27544 1.000 38.61715 ? 401 X77 B N32 1 
HETATM 4624 N N34 . X77 D 2 .   ? -9.98278  32.29193 -51.81427 1.000 37.46952 ? 401 X77 B N34 1 
HETATM 4625 O O01 . X77 D 2 .   ? -9.01472  33.70587 -48.67953 1.000 34.43876 ? 401 X77 B O01 1 
HETATM 4626 O O13 . X77 D 2 .   ? -12.33112 37.07910 -49.82925 1.000 30.43582 ? 401 X77 B O13 1 
HETATM 4627 O O   . HOH E 3 .   ? -21.49332 -0.91833 -17.69033 1.000 32.68049 ? 501 HOH A O   1 
HETATM 4628 O O   . HOH E 3 .   ? -11.42689 11.30997 -30.41400 1.000 24.82232 ? 502 HOH A O   1 
HETATM 4629 O O   . HOH E 3 .   ? -26.95961 13.67774 -18.00127 1.000 25.81258 ? 503 HOH A O   1 
HETATM 4630 O O   . HOH E 3 .   ? -10.64077 -0.82444 -28.25897 1.000 33.81195 ? 504 HOH A O   1 
HETATM 4631 O O   . HOH E 3 .   ? -10.00119 32.33928 -30.08215 1.000 32.85027 ? 505 HOH A O   1 
HETATM 4632 O O   . HOH E 3 .   ? -15.13473 5.49911  -29.07495 1.000 32.55680 ? 506 HOH A O   1 
HETATM 4633 O O   . HOH E 3 .   ? -13.90754 20.16680 -2.95533  1.000 35.61350 ? 507 HOH A O   1 
HETATM 4634 O O   . HOH E 3 .   ? -11.80998 32.51244 -26.29821 1.000 31.40633 ? 508 HOH A O   1 
HETATM 4635 O O   . HOH E 3 .   ? -16.92783 39.72255 -17.43970 1.000 39.77290 ? 509 HOH A O   1 
HETATM 4636 O O   . HOH E 3 .   ? -3.49288  38.13904 -12.56411 1.000 33.27767 ? 510 HOH A O   1 
HETATM 4637 O O   . HOH E 3 .   ? -10.46179 2.48413  -11.57454 1.000 27.49522 ? 511 HOH A O   1 
HETATM 4638 O O   . HOH E 3 .   ? -8.02698  2.93288  -15.23945 1.000 26.14967 ? 512 HOH A O   1 
HETATM 4639 O O   . HOH E 3 .   ? -7.22202  3.74978  -26.37603 1.000 29.56167 ? 513 HOH A O   1 
HETATM 4640 O O   . HOH E 3 .   ? -1.24523  36.25042 -22.77024 1.000 29.45939 ? 514 HOH A O   1 
HETATM 4641 O O   . HOH E 3 .   ? -5.951    -2.091   -22.334   1.000 30.59528 ? 515 HOH A O   1 
HETATM 4642 O O   . HOH E 3 .   ? -26.37162 1.10306  -9.84105  1.000 34.76798 ? 516 HOH A O   1 
HETATM 4643 O O   . HOH E 3 .   ? -25.04535 12.88427 -9.58613  1.000 30.07575 ? 517 HOH A O   1 
HETATM 4644 O O   . HOH E 3 .   ? -9.07566  30.50985 -26.99179 1.000 34.96499 ? 518 HOH A O   1 
HETATM 4645 O O   . HOH E 3 .   ? -26.02834 22.30534 -24.97579 1.000 27.64327 ? 519 HOH A O   1 
HETATM 4646 O O   . HOH E 3 .   ? -17.79301 29.26544 -29.19523 1.000 31.35235 ? 520 HOH A O   1 
HETATM 4647 O O   . HOH E 3 .   ? -5.20914  13.66560 -30.94946 1.000 29.51930 ? 521 HOH A O   1 
HETATM 4648 O O   . HOH E 3 .   ? -14.35178 27.57344 -1.43063  1.000 42.75763 ? 522 HOH A O   1 
HETATM 4649 O O   . HOH E 3 .   ? -1.05569  37.32761 -18.00840 1.000 28.67710 ? 523 HOH A O   1 
HETATM 4650 O O   . HOH E 3 .   ? -0.47826  13.24279 -20.99133 1.000 32.20647 ? 524 HOH A O   1 
HETATM 4651 O O   . HOH E 3 .   ? 2.02080   58.18555 -24.36228 1.000 24.33332 ? 525 HOH A O   1 
HETATM 4652 O O   . HOH E 3 .   ? -18.25183 16.93686 -22.58117 1.000 27.93254 ? 526 HOH A O   1 
HETATM 4653 O O   . HOH E 3 .   ? -26.00332 23.36371 -22.12505 1.000 28.78218 ? 527 HOH A O   1 
HETATM 4654 O O   . HOH E 3 .   ? 0.85716   17.57242 -31.57355 1.000 36.68276 ? 528 HOH A O   1 
HETATM 4655 O O   . HOH E 3 .   ? -18.77790 14.98972 -7.36102  1.000 25.86208 ? 529 HOH A O   1 
HETATM 4656 O O   . HOH E 3 .   ? 5.30105   49.34883 -22.27947 1.000 30.71311 ? 530 HOH A O   1 
HETATM 4657 O O   . HOH E 3 .   ? -6.22915  28.55887 -22.32437 1.000 23.94776 ? 531 HOH A O   1 
HETATM 4658 O O   . HOH E 3 .   ? -5.50461  35.71749 -20.22382 1.000 23.42751 ? 532 HOH A O   1 
HETATM 4659 O O   . HOH E 3 .   ? -19.73480 31.85353 -31.25366 1.000 24.62899 ? 533 HOH A O   1 
HETATM 4660 O O   . HOH E 3 .   ? -19.75317 31.13115 -22.86029 1.000 33.45583 ? 534 HOH A O   1 
HETATM 4661 O O   . HOH E 3 .   ? -21.92072 13.81813 -30.93677 1.000 32.95835 ? 535 HOH A O   1 
HETATM 4662 O O   . HOH E 3 .   ? 4.80151   45.66763 -24.25296 1.000 23.69804 ? 536 HOH A O   1 
HETATM 4663 O O   . HOH E 3 .   ? -22.18545 8.77631  -25.84344 1.000 30.39604 ? 537 HOH A O   1 
HETATM 4664 O O   . HOH E 3 .   ? -5.86873  42.80759 -7.92812  1.000 30.90416 ? 538 HOH A O   1 
HETATM 4665 O O   . HOH E 3 .   ? 2.18924   55.85164 -27.79232 1.000 29.72447 ? 539 HOH A O   1 
HETATM 4666 O O   . HOH E 3 .   ? -6.67518  31.75829 -25.30142 1.000 25.89540 ? 540 HOH A O   1 
HETATM 4667 O O   . HOH E 3 .   ? -18.28071 16.93156 -0.35745  1.000 36.99502 ? 541 HOH A O   1 
HETATM 4668 O O   . HOH E 3 .   ? -8.80245  22.77637 -9.59416  1.000 29.00421 ? 542 HOH A O   1 
HETATM 4669 O O   . HOH E 3 .   ? -2.45658  52.09066 -34.02139 1.000 42.63631 ? 543 HOH A O   1 
HETATM 4670 O O   . HOH E 3 .   ? -15.03963 31.69854 -5.09769  1.000 33.19202 ? 544 HOH A O   1 
HETATM 4671 O O   . HOH E 3 .   ? 3.76237   42.48278 -33.28154 1.000 28.38450 ? 545 HOH A O   1 
HETATM 4672 O O   . HOH E 3 .   ? -6.91738  52.56145 -34.49249 1.000 33.11602 ? 546 HOH A O   1 
HETATM 4673 O O   . HOH E 3 .   ? -16.51285 12.50623 -33.08821 1.000 27.64065 ? 547 HOH A O   1 
HETATM 4674 O O   . HOH E 3 .   ? -0.30991  34.97291 -29.04932 1.000 29.80523 ? 548 HOH A O   1 
HETATM 4675 O O   . HOH E 3 .   ? -7.09572  56.97422 -21.97981 1.000 30.36467 ? 549 HOH A O   1 
HETATM 4676 O O   . HOH E 3 .   ? -4.49921  56.33756 -22.50686 1.000 26.10639 ? 550 HOH A O   1 
HETATM 4677 O O   . HOH E 3 .   ? 4.81778   49.95180 -15.99460 1.000 30.49708 ? 551 HOH A O   1 
HETATM 4678 O O   . HOH E 3 .   ? -7.26892  8.64156  -18.14930 1.000 24.90345 ? 552 HOH A O   1 
HETATM 4679 O O   . HOH E 3 .   ? -10.16531 5.08983  -4.41530  1.000 33.31097 ? 553 HOH A O   1 
HETATM 4680 O O   . HOH E 3 .   ? -5.28733  12.57378 -12.77036 1.000 32.26247 ? 554 HOH A O   1 
HETATM 4681 O O   . HOH E 3 .   ? -8.98808  26.34839 -6.98658  1.000 33.37847 ? 555 HOH A O   1 
HETATM 4682 O O   . HOH E 3 .   ? -7.23311  18.87873 -15.46365 1.000 23.74490 ? 556 HOH A O   1 
HETATM 4683 O O   . HOH E 3 .   ? -19.04401 15.10579 1.37957   1.000 39.11829 ? 557 HOH A O   1 
HETATM 4684 O O   . HOH E 3 .   ? -2.95515  39.45482 -15.63752 1.000 33.26307 ? 558 HOH A O   1 
HETATM 4685 O O   . HOH E 3 .   ? 4.48816   42.51389 -20.86832 1.000 32.51593 ? 559 HOH A O   1 
HETATM 4686 O O   . HOH E 3 .   ? -18.99647 13.22029 -33.56156 1.000 38.17442 ? 560 HOH A O   1 
HETATM 4687 O O   . HOH E 3 .   ? -1.13483  15.29560 -18.08052 1.000 32.07461 ? 561 HOH A O   1 
HETATM 4688 O O   . HOH E 3 .   ? 5.264     54.095   -19.969   1.000 28.50810 ? 562 HOH A O   1 
HETATM 4689 O O   . HOH E 3 .   ? -11.30204 19.72998 -4.19400  1.000 28.55628 ? 563 HOH A O   1 
HETATM 4690 O O   . HOH E 3 .   ? 5.903     49.538   -32.259   1.000 31.25983 ? 564 HOH A O   1 
HETATM 4691 O O   . HOH E 3 .   ? -4.36989  28.38694 -17.56994 1.000 22.43484 ? 565 HOH A O   1 
HETATM 4692 O O   . HOH E 3 .   ? -5.231    1.549    -22.723   1.000 28.58372 ? 566 HOH A O   1 
HETATM 4693 O O   . HOH E 3 .   ? -1.80265  10.92407 -22.05528 1.000 29.57299 ? 567 HOH A O   1 
HETATM 4694 O O   . HOH E 3 .   ? -11.47684 40.56478 -23.40441 1.000 21.77584 ? 568 HOH A O   1 
HETATM 4695 O O   . HOH E 3 .   ? 1.59793   55.53606 -13.00901 1.000 29.22663 ? 569 HOH A O   1 
HETATM 4696 O O   . HOH E 3 .   ? -11.65014 12.05415 -2.21765  1.000 29.28089 ? 570 HOH A O   1 
HETATM 4697 O O   . HOH E 3 .   ? -0.88132  56.56712 -28.77502 1.000 29.59256 ? 571 HOH A O   1 
HETATM 4698 O O   . HOH E 3 .   ? -0.85724  59.57701 -15.38349 1.000 34.14486 ? 572 HOH A O   1 
HETATM 4699 O O   . HOH E 3 .   ? -13.63450 29.99633 -3.68354  1.000 36.76172 ? 573 HOH A O   1 
HETATM 4700 O O   . HOH E 3 .   ? 3.79968   42.73987 -16.28738 1.000 35.16321 ? 574 HOH A O   1 
HETATM 4701 O O   . HOH E 3 .   ? -20.42770 -2.25711 -15.85692 1.000 34.68701 ? 575 HOH A O   1 
HETATM 4702 O O   . HOH E 3 .   ? -4.74328  33.50999 -21.69873 1.000 25.29615 ? 576 HOH A O   1 
HETATM 4703 O O   . HOH E 3 .   ? -9.41081  -2.82689 -25.50628 1.000 29.13520 ? 577 HOH A O   1 
HETATM 4704 O O   . HOH E 3 .   ? -5.22858  18.90645 -13.45585 1.000 32.17364 ? 578 HOH A O   1 
HETATM 4705 O O   . HOH E 3 .   ? -5.22389  39.09666 -9.21600  1.000 30.52562 ? 579 HOH A O   1 
HETATM 4706 O O   . HOH E 3 .   ? -7.95972  34.97348 -8.77810  1.000 36.02739 ? 580 HOH A O   1 
HETATM 4707 O O   . HOH E 3 .   ? -2.10849  57.67773 -14.11259 1.000 30.91453 ? 581 HOH A O   1 
HETATM 4708 O O   . HOH E 3 .   ? 3.82601   50.23793 -28.29851 1.000 28.17630 ? 582 HOH A O   1 
HETATM 4709 O O   . HOH E 3 .   ? -19.59000 34.91215 -31.19041 1.000 28.20084 ? 583 HOH A O   1 
HETATM 4710 O O   . HOH E 3 .   ? 2.45936   34.96193 -24.35399 1.000 31.60780 ? 584 HOH A O   1 
HETATM 4711 O O   . HOH E 3 .   ? 0.64237   60.01291 -17.76045 1.000 27.88382 ? 585 HOH A O   1 
HETATM 4712 O O   . HOH E 3 .   ? -6.18181  3.32255  -19.39099 1.000 21.78883 ? 586 HOH A O   1 
HETATM 4713 O O   . HOH E 3 .   ? -2.51212  61.63419 -16.10386 1.000 36.40795 ? 587 HOH A O   1 
HETATM 4714 O O   . HOH E 3 .   ? -8.39128  -3.18365 -22.95789 1.000 30.29037 ? 588 HOH A O   1 
HETATM 4715 O O   . HOH E 3 .   ? -11.61421 28.02530 -26.45273 1.000 26.73223 ? 589 HOH A O   1 
HETATM 4716 O O   . HOH E 3 .   ? -12.89329 33.29026 -28.53025 1.000 31.48799 ? 590 HOH A O   1 
HETATM 4717 O O   . HOH E 3 .   ? -11.68616 -1.66766 -8.03554  1.000 33.93663 ? 591 HOH A O   1 
HETATM 4718 O O   . HOH E 3 .   ? -9.50922  -3.41119 -18.38993 1.000 30.75138 ? 592 HOH A O   1 
HETATM 4719 O O   . HOH E 3 .   ? -6.28686  31.28905 -22.55064 1.000 21.79659 ? 593 HOH A O   1 
HETATM 4720 O O   . HOH E 3 .   ? -16.02093 -4.74665 -7.15123  1.000 36.77220 ? 594 HOH A O   1 
HETATM 4721 O O   . HOH E 3 .   ? 3.84265   48.23609 -24.01032 1.000 25.61400 ? 595 HOH A O   1 
HETATM 4722 O O   . HOH E 3 .   ? -13.63712 32.57663 -23.91863 1.000 32.82889 ? 596 HOH A O   1 
HETATM 4723 O O   . HOH E 3 .   ? -5.81282  40.45788 -7.18998  1.000 38.44876 ? 597 HOH A O   1 
HETATM 4724 O O   . HOH E 3 .   ? -9.60025  57.46890 -21.58302 1.000 39.16769 ? 598 HOH A O   1 
HETATM 4725 O O   . HOH E 3 .   ? -3.02729  17.17658 -13.36706 1.000 38.06583 ? 599 HOH A O   1 
HETATM 4726 O O   . HOH E 3 .   ? -5.00243  35.59006 -17.50134 1.000 26.82829 ? 600 HOH A O   1 
HETATM 4727 O O   . HOH E 3 .   ? -7.79115  9.39913  -32.08368 1.000 43.27126 ? 601 HOH A O   1 
HETATM 4728 O O   . HOH E 3 .   ? -8.65932  -4.75322 -20.48492 1.000 33.80785 ? 602 HOH A O   1 
HETATM 4729 O O   . HOH E 3 .   ? -5.67462  36.51883 -13.07397 1.000 30.09074 ? 603 HOH A O   1 
HETATM 4730 O O   . HOH E 3 .   ? 4.05453   54.34931 -17.54419 1.000 29.25167 ? 604 HOH A O   1 
HETATM 4731 O O   . HOH E 3 .   ? -5.860    5.369    -32.896   1.000 35.37389 ? 605 HOH A O   1 
HETATM 4732 O O   . HOH E 3 .   ? 3.020     59.449   -17.219   1.000 31.27332 ? 606 HOH A O   1 
HETATM 4733 O O   . HOH E 3 .   ? 3.72820   44.45733 -19.00072 1.000 32.88936 ? 607 HOH A O   1 
HETATM 4734 O O   . HOH E 3 .   ? -3.55745  14.25032 -13.03809 1.000 35.25932 ? 608 HOH A O   1 
HETATM 4735 O O   . HOH E 3 .   ? -4.52719  10.31225 -14.04913 1.000 32.53709 ? 609 HOH A O   1 
HETATM 4736 O O   . HOH E 3 .   ? -12.45282 11.05374 -33.19066 1.000 27.73970 ? 610 HOH A O   1 
HETATM 4737 O O   . HOH E 3 .   ? -5.38362  27.85974 -24.86923 1.000 31.85138 ? 611 HOH A O   1 
HETATM 4738 O O   . HOH E 3 .   ? -8.22020  27.76306 -5.01758  1.000 46.06169 ? 612 HOH A O   1 
HETATM 4739 O O   . HOH E 3 .   ? -4.52540  30.34256 -25.93082 1.000 33.52985 ? 613 HOH A O   1 
HETATM 4740 O O   . HOH E 3 .   ? -2.52754  36.41237 -20.37862 1.000 29.20926 ? 614 HOH A O   1 
HETATM 4741 O O   . HOH E 3 .   ? -7.58660  25.23589 -9.27563  1.000 31.16352 ? 615 HOH A O   1 
HETATM 4742 O O   . HOH E 3 .   ? -6.59976  36.19003 -10.50502 1.000 33.56068 ? 616 HOH A O   1 
HETATM 4743 O O   . HOH E 3 .   ? -3.56915  29.68541 -28.15301 1.000 38.50828 ? 617 HOH A O   1 
HETATM 4744 O O   . HOH F 3 .   ? -15.89903 10.41373 -43.42800 1.000 31.67082 ? 501 HOH B O   1 
HETATM 4745 O O   . HOH F 3 .   ? -27.22676 32.75176 -31.14607 1.000 37.64687 ? 502 HOH B O   1 
HETATM 4746 O O   . HOH F 3 .   ? -29.13517 29.15331 -31.89862 1.000 31.44316 ? 503 HOH B O   1 
HETATM 4747 O O   . HOH F 3 .   ? -10.47104 30.01876 -54.92076 1.000 33.52497 ? 504 HOH B O   1 
HETATM 4748 O O   . HOH F 3 .   ? -16.49149 23.72368 -42.55820 1.000 31.50660 ? 505 HOH B O   1 
HETATM 4749 O O   . HOH F 3 .   ? -38.25871 32.14019 -33.74065 1.000 32.61918 ? 506 HOH B O   1 
HETATM 4750 O O   . HOH F 3 .   ? -10.73154 28.75425 -36.74664 1.000 25.25418 ? 507 HOH B O   1 
HETATM 4751 O O   . HOH F 3 .   ? -21.16522 35.54719 -33.15249 1.000 29.04384 ? 508 HOH B O   1 
HETATM 4752 O O   . HOH F 3 .   ? -38.08449 27.48506 -29.24146 1.000 33.23563 ? 509 HOH B O   1 
HETATM 4753 O O   . HOH F 3 .   ? -8.42012  13.84724 -56.32766 1.000 33.25545 ? 510 HOH B O   1 
HETATM 4754 O O   . HOH F 3 .   ? -20.70586 16.19976 -60.51908 1.000 34.97506 ? 511 HOH B O   1 
HETATM 4755 O O   . HOH F 3 .   ? -33.12127 41.69963 -44.82883 1.000 36.99318 ? 512 HOH B O   1 
HETATM 4756 O O   . HOH F 3 .   ? -17.26772 4.44404  -48.64488 1.000 37.28518 ? 513 HOH B O   1 
HETATM 4757 O O   . HOH F 3 .   ? -31.68248 29.79720 -32.96160 1.000 29.15935 ? 514 HOH B O   1 
HETATM 4758 O O   . HOH F 3 .   ? -38.27569 46.85736 -42.38229 1.000 34.16989 ? 515 HOH B O   1 
HETATM 4759 O O   . HOH F 3 .   ? -23.97548 35.81564 -56.97649 1.000 38.97326 ? 516 HOH B O   1 
HETATM 4760 O O   . HOH F 3 .   ? -40.92080 46.26644 -42.08217 1.000 32.60387 ? 517 HOH B O   1 
HETATM 4761 O O   . HOH F 3 .   ? -20.56300 12.64562 -39.94807 1.000 24.68706 ? 518 HOH B O   1 
HETATM 4762 O O   . HOH F 3 .   ? -23.53114 37.89934 -38.24930 1.000 25.40445 ? 519 HOH B O   1 
HETATM 4763 O O   . HOH F 3 .   ? -17.32653 30.80661 -56.07568 1.000 28.03603 ? 520 HOH B O   1 
HETATM 4764 O O   . HOH F 3 .   ? -20.72831 37.39425 -35.00415 1.000 29.69788 ? 521 HOH B O   1 
HETATM 4765 O O   . HOH F 3 .   ? -28.36028 25.52392 -48.38604 1.000 28.73244 ? 522 HOH B O   1 
HETATM 4766 O O   . HOH F 3 .   ? -7.74095  26.40800 -47.40271 1.000 28.83414 ? 523 HOH B O   1 
HETATM 4767 O O   . HOH F 3 .   ? -26.18042 43.85471 -34.17117 1.000 39.56114 ? 524 HOH B O   1 
HETATM 4768 O O   . HOH F 3 .   ? -25.92564 43.72196 -48.73129 1.000 33.11842 ? 525 HOH B O   1 
HETATM 4769 O O   . HOH F 3 .   ? -11.34290 31.08790 -38.35425 1.000 25.03706 ? 526 HOH B O   1 
HETATM 4770 O O   . HOH F 3 .   ? -44.90434 48.40201 -23.85442 1.000 28.24861 ? 527 HOH B O   1 
HETATM 4771 O O   . HOH F 3 .   ? -25.78554 32.86291 -33.43189 1.000 33.61466 ? 528 HOH B O   1 
HETATM 4772 O O   . HOH F 3 .   ? -45.47957 39.78768 -39.86752 1.000 34.95476 ? 529 HOH B O   1 
HETATM 4773 O O   . HOH F 3 .   ? -31.62124 28.68546 -37.29145 1.000 30.56953 ? 530 HOH B O   1 
HETATM 4774 O O   . HOH F 3 .   ? -43.402   29.066   -35.680   1.000 31.44348 ? 531 HOH B O   1 
HETATM 4775 O O   . HOH F 3 .   ? -31.06001 39.09822 -29.37419 1.000 21.29832 ? 532 HOH B O   1 
HETATM 4776 O O   . HOH F 3 .   ? -9.95932  16.60750 -44.46770 1.000 31.49531 ? 533 HOH B O   1 
HETATM 4777 O O   . HOH F 3 .   ? -21.53477 16.22504 -34.23099 1.000 27.75858 ? 534 HOH B O   1 
HETATM 4778 O O   . HOH F 3 .   ? -26.10926 31.02679 -29.14645 1.000 33.24272 ? 535 HOH B O   1 
HETATM 4779 O O   . HOH F 3 .   ? -25.21663 35.39344 -32.84011 1.000 35.20663 ? 536 HOH B O   1 
HETATM 4780 O O   . HOH F 3 .   ? -51.59472 45.91010 -22.92197 1.000 34.53013 ? 537 HOH B O   1 
HETATM 4781 O O   . HOH F 3 .   ? -39.18583 35.31047 -37.36172 1.000 29.38790 ? 538 HOH B O   1 
HETATM 4782 O O   . HOH F 3 .   ? -32.75060 19.58495 -48.93772 1.000 39.66278 ? 539 HOH B O   1 
HETATM 4783 O O   . HOH F 3 .   ? -34.73493 34.76147 -35.40557 1.000 27.04021 ? 540 HOH B O   1 
HETATM 4784 O O   . HOH F 3 .   ? -18.41567 15.65201 -65.53808 1.000 36.96927 ? 541 HOH B O   1 
HETATM 4785 O O   . HOH F 3 .   ? -30.08902 36.46750 -50.67250 1.000 32.42228 ? 542 HOH B O   1 
HETATM 4786 O O   . HOH F 3 .   ? -26.98741 20.12274 -31.07195 1.000 30.39489 ? 543 HOH B O   1 
HETATM 4787 O O   . HOH F 3 .   ? -24.58430 39.66904 -35.65652 1.000 31.09413 ? 544 HOH B O   1 
HETATM 4788 O O   . HOH F 3 .   ? -25.86967 33.96439 -56.63683 1.000 33.69522 ? 545 HOH B O   1 
HETATM 4789 O O   . HOH F 3 .   ? -19.00213 30.58657 -26.80212 1.000 29.01973 ? 546 HOH B O   1 
HETATM 4790 O O   . HOH F 3 .   ? -12.11998 17.59001 -33.07329 1.000 26.46710 ? 547 HOH B O   1 
HETATM 4791 O O   . HOH F 3 .   ? -34.05443 30.69453 -41.47206 1.000 33.45078 ? 548 HOH B O   1 
HETATM 4792 O O   . HOH F 3 .   ? -34.40615 32.04303 -35.35197 1.000 30.10443 ? 549 HOH B O   1 
HETATM 4793 O O   . HOH F 3 .   ? -20.35718 29.48907 -30.07301 1.000 33.24074 ? 550 HOH B O   1 
HETATM 4794 O O   . HOH F 3 .   ? -38.63276 45.19382 -13.70626 1.000 46.26732 ? 551 HOH B O   1 
HETATM 4795 O O   . HOH F 3 .   ? -32.30201 30.59215 -35.55777 1.000 26.60789 ? 552 HOH B O   1 
HETATM 4796 O O   . HOH F 3 .   ? -46.02097 37.85754 -37.93633 1.000 34.91131 ? 553 HOH B O   1 
HETATM 4797 O O   . HOH F 3 .   ? -30.51245 25.94858 -50.04682 1.000 32.02617 ? 554 HOH B O   1 
HETATM 4798 O O   . HOH F 3 .   ? -17.93450 4.04221  -51.68905 1.000 32.70630 ? 555 HOH B O   1 
HETATM 4799 O O   . HOH F 3 .   ? -20.63342 33.53703 -25.17383 1.000 27.39395 ? 556 HOH B O   1 
HETATM 4800 O O   . HOH F 3 .   ? -37.29079 43.07922 -43.31914 1.000 32.84585 ? 557 HOH B O   1 
HETATM 4801 O O   . HOH F 3 .   ? -5.43117  19.94542 -58.97270 1.000 36.70571 ? 558 HOH B O   1 
HETATM 4802 O O   . HOH F 3 .   ? -48.04176 37.95155 -27.87367 1.000 32.68014 ? 559 HOH B O   1 
HETATM 4803 O O   . HOH F 3 .   ? -23.67441 37.11520 -35.17673 1.000 24.83225 ? 560 HOH B O   1 
HETATM 4804 O O   . HOH F 3 .   ? -26.93952 26.21847 -31.16822 1.000 32.84092 ? 561 HOH B O   1 
HETATM 4805 O O   . HOH F 3 .   ? -27.82625 11.15605 -47.23121 1.000 44.89215 ? 562 HOH B O   1 
HETATM 4806 O O   . HOH F 3 .   ? -25.76818 31.95755 -58.74629 1.000 36.09985 ? 563 HOH B O   1 
HETATM 4807 O O   . HOH F 3 .   ? -37.46754 33.85453 -35.61740 1.000 30.84513 ? 564 HOH B O   1 
HETATM 4808 O O   . HOH F 3 .   ? -32.82096 27.25168 -33.22948 1.000 37.36831 ? 565 HOH B O   1 
HETATM 4809 O O   . HOH F 3 .   ? -49.30075 37.51909 -25.82020 1.000 38.61852 ? 566 HOH B O   1 
HETATM 4810 O O   . HOH F 3 .   ? -31.91790 26.46149 -35.83537 1.000 35.47220 ? 567 HOH B O   1 
HETATM 4811 O O   . HOH F 3 .   ? -35.98890 32.22672 -40.01338 1.000 36.58054 ? 568 HOH B O   1 
HETATM 4812 O O   . HOH F 3 .   ? -32.82376 28.44341 -39.75755 1.000 31.98946 ? 569 HOH B O   1 
HETATM 4813 O O   . HOH F 3 .   ? -30.81209 33.98706 -49.70210 1.000 29.67736 ? 570 HOH B O   1 
# 
