data_8YH0
# 
_entry.id   8YH0 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8YH0         pdb_00008yh0 10.2210/pdb8yh0/pdb 
WWPDB D_1300045571 ?            ?                   
EMDB  EMD-39278    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_CSD'          
4  2 'Structure model' '_citation.journal_id_ISSN'         
5  2 'Structure model' '_citation.journal_volume'          
6  2 'Structure model' '_citation.page_first'              
7  2 'Structure model' '_citation.page_last'               
8  2 'Structure model' '_citation.pdbx_database_id_DOI'    
9  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
10 2 'Structure model' '_citation.title'                   
11 2 'Structure model' '_citation.year'                    
12 2 'Structure model' '_citation_author.identifier_ORCID' 
13 2 'Structure model' '_citation_author.name'             
14 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8YH0 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'A3R-Gi complex bound to NECA' EMD-39278 'associated EM volume' 
EMDB .                              EMD-61664 'focused EM volume'    
EMDB .                              EMD-61666 'focused EM volume'    
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              nureki@bs.s.u-tokyo.ac.jp 
_pdbx_contact_author.name_first         Osamu 
_pdbx_contact_author.name_last          Nureki 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1813-7008 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Oshima, H.S.' 1 0009-0000-0341-707X 
'Shihoya, W.'  2 0000-0003-4813-5740 
'Nureki, O.'   3 0000-0003-1813-7008 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                9294 
_citation.page_last                 9294 
_citation.title                     'Structural insights into the agonist selectivity of the adenosine A 3 receptor.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-53473-1 
_citation.pdbx_database_id_PubMed   39511145 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Oshima, H.S.'  1  0009-0000-0341-707X 
primary 'Ogawa, A.'     2  ?                   
primary 'Sano, F.K.'    3  0000-0002-8965-788X 
primary 'Akasaka, H.'   4  0000-0003-2118-0912 
primary 'Kawakami, T.'  5  ?                   
primary 'Iwama, A.'     6  ?                   
primary 'Okamoto, H.H.' 7  ?                   
primary 'Nagiri, C.'    8  ?                   
primary 'Wei, F.Y.'     9  0000-0002-4843-724X 
primary 'Shihoya, W.'   10 0000-0003-4813-5740 
primary 'Nureki, O.'    11 0000-0003-1813-7008 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'HA tag,Adenosine receptor A3,LgBiT,eGFP chimera' 88315.891 1 ? ? ? 'FLAG tag (DYKDDDDK)' 
2 polymer     man 
'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-1' 
48846.695 2 ? ? ? ?                     
3 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1' 40586.332 1 ? ? ? ?                     
4 polymer     man scfv16 27720.795 1 ? ? ? ?                     
5 non-polymer syn 
;N-ETHYL-5'-CARBOXAMIDO ADENOSINE
;
308.293   1 ? ? ? ?                     
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
2 'G gamma-I,Adenylate cyclase-inhibiting G alpha protein' 
3 'Transducin beta chain 1'                                
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MKTIIALSYIFCLVFADYKDDDDAMGPVNSTAVSWTSVTYITVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLA
LADIAVGVLVMPLAIVISLGVTIHFYSCLFMTCLMLIFTHASIMSLLAIAVDRYLRVKLTVRYRRVTTQRRIWLALGLCW
LVSFLVGLTPMFGWNMKLSSADENLTFLPCRFRSVMRMDYMVYFSFFLWILVPLVVMCAIYFDIFYIIRNRLSQSFSGSR
ETGAFYGREFKTAKSLLLVLFLFALCWLPLSIINCILYFDGQVPQTVLYLGILLSHANSMMNPIVYAYKIKKFKETYLLI
LKACVICQPSKSMDPSTEQTSEGSGGGGSGGSSSGGVFTLEDFVGDWEQTAAYNLDQVLEQGGVSSLLQNLAVSVTPIQR
IVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILPYGTLVIDGVTPNMLNYFGRPYEGIAVFDGK
KITVTGTLWNGNKIIDERLITPDGSMLFRVTINSGGSGGGGSGGSSSGGLEVLFQGPGSAAAAVSKGEELFTGVVPILVE
LDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERT
IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQ
LADHYQQNTPIGDGPVLLPDNHYLSTQSKLSKDPNEKRDHMVLLEFVTAAGITLGMDELYKSGLRSHHHHHHHH
;
;MKTIIALSYIFCLVFADYKDDDDAMGPVNSTAVSWTSVTYITVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLA
LADIAVGVLVMPLAIVISLGVTIHFYSCLFMTCLMLIFTHASIMSLLAIAVDRYLRVKLTVRYRRVTTQRRIWLALGLCW
LVSFLVGLTPMFGWNMKLSSADENLTFLPCRFRSVMRMDYMVYFSFFLWILVPLVVMCAIYFDIFYIIRNRLSQSFSGSR
ETGAFYGREFKTAKSLLLVLFLFALCWLPLSIINCILYFDGQVPQTVLYLGILLSHANSMMNPIVYAYKIKKFKETYLLI
LKACVICQPSKSMDPSTEQTSEGSGGGGSGGSSSGGVFTLEDFVGDWEQTAAYNLDQVLEQGGVSSLLQNLAVSVTPIQR
IVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILPYGTLVIDGVTPNMLNYFGRPYEGIAVFDGK
KITVTGTLWNGNKIIDERLITPDGSMLFRVTINSGGSGGGGSGGSSSGGLEVLFQGPGSAAAAVSKGEELFTGVVPILVE
LDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERT
IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQ
LADHYQQNTPIGDGPVLLPDNHYLSTQSKLSKDPNEKRDHMVLLEFVTAAGITLGMDELYKSGLRSHHHHHHHH
;
R   ? 
2 'polypeptide(L)' no no 
;MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAILGSAGSAGSA
MCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSI
IAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDR
IAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMN
RMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYT
HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAILGSAGSAGSA
MCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSI
IAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDR
IAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMN
RMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYT
HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
A,G ? 
3 'polypeptide(L)' no no 
;MGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQ
DGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN
QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF
PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV
SCLGVTDDGMAVATGSWDSFLKIWNGASGGGSGGNSGSSGGSSGVSGWRLFKKIS
;
;MGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQ
DGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN
QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF
PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV
SCLGVTDDGMAVATGSWDSFLKIWNGASGGGSGGNSGSSGGSSGVSGWRLFKKIS
;
B   ? 
4 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAAASSEDLYFQ
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAAASSEDLYFQ
;
S   ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        
;N-ETHYL-5'-CARBOXAMIDO ADENOSINE
;
_pdbx_entity_nonpoly.comp_id     NEC 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   THR n 
1 4   ILE n 
1 5   ILE n 
1 6   ALA n 
1 7   LEU n 
1 8   SER n 
1 9   TYR n 
1 10  ILE n 
1 11  PHE n 
1 12  CYS n 
1 13  LEU n 
1 14  VAL n 
1 15  PHE n 
1 16  ALA n 
1 17  ASP n 
1 18  TYR n 
1 19  LYS n 
1 20  ASP n 
1 21  ASP n 
1 22  ASP n 
1 23  ASP n 
1 24  ALA n 
1 25  MET n 
1 26  GLY n 
1 27  PRO n 
1 28  VAL n 
1 29  ASN n 
1 30  SER n 
1 31  THR n 
1 32  ALA n 
1 33  VAL n 
1 34  SER n 
1 35  TRP n 
1 36  THR n 
1 37  SER n 
1 38  VAL n 
1 39  THR n 
1 40  TYR n 
1 41  ILE n 
1 42  THR n 
1 43  VAL n 
1 44  GLU n 
1 45  ILE n 
1 46  LEU n 
1 47  ILE n 
1 48  GLY n 
1 49  LEU n 
1 50  CYS n 
1 51  ALA n 
1 52  ILE n 
1 53  VAL n 
1 54  GLY n 
1 55  ASN n 
1 56  VAL n 
1 57  LEU n 
1 58  VAL n 
1 59  ILE n 
1 60  TRP n 
1 61  VAL n 
1 62  VAL n 
1 63  LYS n 
1 64  LEU n 
1 65  ASN n 
1 66  PRO n 
1 67  SER n 
1 68  LEU n 
1 69  GLN n 
1 70  THR n 
1 71  THR n 
1 72  THR n 
1 73  PHE n 
1 74  TYR n 
1 75  PHE n 
1 76  ILE n 
1 77  VAL n 
1 78  SER n 
1 79  LEU n 
1 80  ALA n 
1 81  LEU n 
1 82  ALA n 
1 83  ASP n 
1 84  ILE n 
1 85  ALA n 
1 86  VAL n 
1 87  GLY n 
1 88  VAL n 
1 89  LEU n 
1 90  VAL n 
1 91  MET n 
1 92  PRO n 
1 93  LEU n 
1 94  ALA n 
1 95  ILE n 
1 96  VAL n 
1 97  ILE n 
1 98  SER n 
1 99  LEU n 
1 100 GLY n 
1 101 VAL n 
1 102 THR n 
1 103 ILE n 
1 104 HIS n 
1 105 PHE n 
1 106 TYR n 
1 107 SER n 
1 108 CYS n 
1 109 LEU n 
1 110 PHE n 
1 111 MET n 
1 112 THR n 
1 113 CYS n 
1 114 LEU n 
1 115 MET n 
1 116 LEU n 
1 117 ILE n 
1 118 PHE n 
1 119 THR n 
1 120 HIS n 
1 121 ALA n 
1 122 SER n 
1 123 ILE n 
1 124 MET n 
1 125 SER n 
1 126 LEU n 
1 127 LEU n 
1 128 ALA n 
1 129 ILE n 
1 130 ALA n 
1 131 VAL n 
1 132 ASP n 
1 133 ARG n 
1 134 TYR n 
1 135 LEU n 
1 136 ARG n 
1 137 VAL n 
1 138 LYS n 
1 139 LEU n 
1 140 THR n 
1 141 VAL n 
1 142 ARG n 
1 143 TYR n 
1 144 ARG n 
1 145 ARG n 
1 146 VAL n 
1 147 THR n 
1 148 THR n 
1 149 GLN n 
1 150 ARG n 
1 151 ARG n 
1 152 ILE n 
1 153 TRP n 
1 154 LEU n 
1 155 ALA n 
1 156 LEU n 
1 157 GLY n 
1 158 LEU n 
1 159 CYS n 
1 160 TRP n 
1 161 LEU n 
1 162 VAL n 
1 163 SER n 
1 164 PHE n 
1 165 LEU n 
1 166 VAL n 
1 167 GLY n 
1 168 LEU n 
1 169 THR n 
1 170 PRO n 
1 171 MET n 
1 172 PHE n 
1 173 GLY n 
1 174 TRP n 
1 175 ASN n 
1 176 MET n 
1 177 LYS n 
1 178 LEU n 
1 179 SER n 
1 180 SER n 
1 181 ALA n 
1 182 ASP n 
1 183 GLU n 
1 184 ASN n 
1 185 LEU n 
1 186 THR n 
1 187 PHE n 
1 188 LEU n 
1 189 PRO n 
1 190 CYS n 
1 191 ARG n 
1 192 PHE n 
1 193 ARG n 
1 194 SER n 
1 195 VAL n 
1 196 MET n 
1 197 ARG n 
1 198 MET n 
1 199 ASP n 
1 200 TYR n 
1 201 MET n 
1 202 VAL n 
1 203 TYR n 
1 204 PHE n 
1 205 SER n 
1 206 PHE n 
1 207 PHE n 
1 208 LEU n 
1 209 TRP n 
1 210 ILE n 
1 211 LEU n 
1 212 VAL n 
1 213 PRO n 
1 214 LEU n 
1 215 VAL n 
1 216 VAL n 
1 217 MET n 
1 218 CYS n 
1 219 ALA n 
1 220 ILE n 
1 221 TYR n 
1 222 PHE n 
1 223 ASP n 
1 224 ILE n 
1 225 PHE n 
1 226 TYR n 
1 227 ILE n 
1 228 ILE n 
1 229 ARG n 
1 230 ASN n 
1 231 ARG n 
1 232 LEU n 
1 233 SER n 
1 234 GLN n 
1 235 SER n 
1 236 PHE n 
1 237 SER n 
1 238 GLY n 
1 239 SER n 
1 240 ARG n 
1 241 GLU n 
1 242 THR n 
1 243 GLY n 
1 244 ALA n 
1 245 PHE n 
1 246 TYR n 
1 247 GLY n 
1 248 ARG n 
1 249 GLU n 
1 250 PHE n 
1 251 LYS n 
1 252 THR n 
1 253 ALA n 
1 254 LYS n 
1 255 SER n 
1 256 LEU n 
1 257 LEU n 
1 258 LEU n 
1 259 VAL n 
1 260 LEU n 
1 261 PHE n 
1 262 LEU n 
1 263 PHE n 
1 264 ALA n 
1 265 LEU n 
1 266 CYS n 
1 267 TRP n 
1 268 LEU n 
1 269 PRO n 
1 270 LEU n 
1 271 SER n 
1 272 ILE n 
1 273 ILE n 
1 274 ASN n 
1 275 CYS n 
1 276 ILE n 
1 277 LEU n 
1 278 TYR n 
1 279 PHE n 
1 280 ASP n 
1 281 GLY n 
1 282 GLN n 
1 283 VAL n 
1 284 PRO n 
1 285 GLN n 
1 286 THR n 
1 287 VAL n 
1 288 LEU n 
1 289 TYR n 
1 290 LEU n 
1 291 GLY n 
1 292 ILE n 
1 293 LEU n 
1 294 LEU n 
1 295 SER n 
1 296 HIS n 
1 297 ALA n 
1 298 ASN n 
1 299 SER n 
1 300 MET n 
1 301 MET n 
1 302 ASN n 
1 303 PRO n 
1 304 ILE n 
1 305 VAL n 
1 306 TYR n 
1 307 ALA n 
1 308 TYR n 
1 309 LYS n 
1 310 ILE n 
1 311 LYS n 
1 312 LYS n 
1 313 PHE n 
1 314 LYS n 
1 315 GLU n 
1 316 THR n 
1 317 TYR n 
1 318 LEU n 
1 319 LEU n 
1 320 ILE n 
1 321 LEU n 
1 322 LYS n 
1 323 ALA n 
1 324 CYS n 
1 325 VAL n 
1 326 ILE n 
1 327 CYS n 
1 328 GLN n 
1 329 PRO n 
1 330 SER n 
1 331 LYS n 
1 332 SER n 
1 333 MET n 
1 334 ASP n 
1 335 PRO n 
1 336 SER n 
1 337 THR n 
1 338 GLU n 
1 339 GLN n 
1 340 THR n 
1 341 SER n 
1 342 GLU n 
1 343 GLY n 
1 344 SER n 
1 345 GLY n 
1 346 GLY n 
1 347 GLY n 
1 348 GLY n 
1 349 SER n 
1 350 GLY n 
1 351 GLY n 
1 352 SER n 
1 353 SER n 
1 354 SER n 
1 355 GLY n 
1 356 GLY n 
1 357 VAL n 
1 358 PHE n 
1 359 THR n 
1 360 LEU n 
1 361 GLU n 
1 362 ASP n 
1 363 PHE n 
1 364 VAL n 
1 365 GLY n 
1 366 ASP n 
1 367 TRP n 
1 368 GLU n 
1 369 GLN n 
1 370 THR n 
1 371 ALA n 
1 372 ALA n 
1 373 TYR n 
1 374 ASN n 
1 375 LEU n 
1 376 ASP n 
1 377 GLN n 
1 378 VAL n 
1 379 LEU n 
1 380 GLU n 
1 381 GLN n 
1 382 GLY n 
1 383 GLY n 
1 384 VAL n 
1 385 SER n 
1 386 SER n 
1 387 LEU n 
1 388 LEU n 
1 389 GLN n 
1 390 ASN n 
1 391 LEU n 
1 392 ALA n 
1 393 VAL n 
1 394 SER n 
1 395 VAL n 
1 396 THR n 
1 397 PRO n 
1 398 ILE n 
1 399 GLN n 
1 400 ARG n 
1 401 ILE n 
1 402 VAL n 
1 403 ARG n 
1 404 SER n 
1 405 GLY n 
1 406 GLU n 
1 407 ASN n 
1 408 ALA n 
1 409 LEU n 
1 410 LYS n 
1 411 ILE n 
1 412 ASP n 
1 413 ILE n 
1 414 HIS n 
1 415 VAL n 
1 416 ILE n 
1 417 ILE n 
1 418 PRO n 
1 419 TYR n 
1 420 GLU n 
1 421 GLY n 
1 422 LEU n 
1 423 SER n 
1 424 ALA n 
1 425 ASP n 
1 426 GLN n 
1 427 MET n 
1 428 ALA n 
1 429 GLN n 
1 430 ILE n 
1 431 GLU n 
1 432 GLU n 
1 433 VAL n 
1 434 PHE n 
1 435 LYS n 
1 436 VAL n 
1 437 VAL n 
1 438 TYR n 
1 439 PRO n 
1 440 VAL n 
1 441 ASP n 
1 442 ASP n 
1 443 HIS n 
1 444 HIS n 
1 445 PHE n 
1 446 LYS n 
1 447 VAL n 
1 448 ILE n 
1 449 LEU n 
1 450 PRO n 
1 451 TYR n 
1 452 GLY n 
1 453 THR n 
1 454 LEU n 
1 455 VAL n 
1 456 ILE n 
1 457 ASP n 
1 458 GLY n 
1 459 VAL n 
1 460 THR n 
1 461 PRO n 
1 462 ASN n 
1 463 MET n 
1 464 LEU n 
1 465 ASN n 
1 466 TYR n 
1 467 PHE n 
1 468 GLY n 
1 469 ARG n 
1 470 PRO n 
1 471 TYR n 
1 472 GLU n 
1 473 GLY n 
1 474 ILE n 
1 475 ALA n 
1 476 VAL n 
1 477 PHE n 
1 478 ASP n 
1 479 GLY n 
1 480 LYS n 
1 481 LYS n 
1 482 ILE n 
1 483 THR n 
1 484 VAL n 
1 485 THR n 
1 486 GLY n 
1 487 THR n 
1 488 LEU n 
1 489 TRP n 
1 490 ASN n 
1 491 GLY n 
1 492 ASN n 
1 493 LYS n 
1 494 ILE n 
1 495 ILE n 
1 496 ASP n 
1 497 GLU n 
1 498 ARG n 
1 499 LEU n 
1 500 ILE n 
1 501 THR n 
1 502 PRO n 
1 503 ASP n 
1 504 GLY n 
1 505 SER n 
1 506 MET n 
1 507 LEU n 
1 508 PHE n 
1 509 ARG n 
1 510 VAL n 
1 511 THR n 
1 512 ILE n 
1 513 ASN n 
1 514 SER n 
1 515 GLY n 
1 516 GLY n 
1 517 SER n 
1 518 GLY n 
1 519 GLY n 
1 520 GLY n 
1 521 GLY n 
1 522 SER n 
1 523 GLY n 
1 524 GLY n 
1 525 SER n 
1 526 SER n 
1 527 SER n 
1 528 GLY n 
1 529 GLY n 
1 530 LEU n 
1 531 GLU n 
1 532 VAL n 
1 533 LEU n 
1 534 PHE n 
1 535 GLN n 
1 536 GLY n 
1 537 PRO n 
1 538 GLY n 
1 539 SER n 
1 540 ALA n 
1 541 ALA n 
1 542 ALA n 
1 543 ALA n 
1 544 VAL n 
1 545 SER n 
1 546 LYS n 
1 547 GLY n 
1 548 GLU n 
1 549 GLU n 
1 550 LEU n 
1 551 PHE n 
1 552 THR n 
1 553 GLY n 
1 554 VAL n 
1 555 VAL n 
1 556 PRO n 
1 557 ILE n 
1 558 LEU n 
1 559 VAL n 
1 560 GLU n 
1 561 LEU n 
1 562 ASP n 
1 563 GLY n 
1 564 ASP n 
1 565 VAL n 
1 566 ASN n 
1 567 GLY n 
1 568 HIS n 
1 569 LYS n 
1 570 PHE n 
1 571 SER n 
1 572 VAL n 
1 573 SER n 
1 574 GLY n 
1 575 GLU n 
1 576 GLY n 
1 577 GLU n 
1 578 GLY n 
1 579 ASP n 
1 580 ALA n 
1 581 THR n 
1 582 TYR n 
1 583 GLY n 
1 584 LYS n 
1 585 LEU n 
1 586 THR n 
1 587 LEU n 
1 588 LYS n 
1 589 PHE n 
1 590 ILE n 
1 591 CYS n 
1 592 THR n 
1 593 THR n 
1 594 GLY n 
1 595 LYS n 
1 596 LEU n 
1 597 PRO n 
1 598 VAL n 
1 599 PRO n 
1 600 TRP n 
1 601 PRO n 
1 602 THR n 
1 603 LEU n 
1 604 VAL n 
1 605 THR n 
1 606 THR n 
1 607 LEU n 
1 608 THR n 
1 609 TYR n 
1 610 GLY n 
1 611 VAL n 
1 612 GLN n 
1 613 CYS n 
1 614 PHE n 
1 615 SER n 
1 616 ARG n 
1 617 TYR n 
1 618 PRO n 
1 619 ASP n 
1 620 HIS n 
1 621 MET n 
1 622 LYS n 
1 623 GLN n 
1 624 HIS n 
1 625 ASP n 
1 626 PHE n 
1 627 PHE n 
1 628 LYS n 
1 629 SER n 
1 630 ALA n 
1 631 MET n 
1 632 PRO n 
1 633 GLU n 
1 634 GLY n 
1 635 TYR n 
1 636 VAL n 
1 637 GLN n 
1 638 GLU n 
1 639 ARG n 
1 640 THR n 
1 641 ILE n 
1 642 PHE n 
1 643 PHE n 
1 644 LYS n 
1 645 ASP n 
1 646 ASP n 
1 647 GLY n 
1 648 ASN n 
1 649 TYR n 
1 650 LYS n 
1 651 THR n 
1 652 ARG n 
1 653 ALA n 
1 654 GLU n 
1 655 VAL n 
1 656 LYS n 
1 657 PHE n 
1 658 GLU n 
1 659 GLY n 
1 660 ASP n 
1 661 THR n 
1 662 LEU n 
1 663 VAL n 
1 664 ASN n 
1 665 ARG n 
1 666 ILE n 
1 667 GLU n 
1 668 LEU n 
1 669 LYS n 
1 670 GLY n 
1 671 ILE n 
1 672 ASP n 
1 673 PHE n 
1 674 LYS n 
1 675 GLU n 
1 676 ASP n 
1 677 GLY n 
1 678 ASN n 
1 679 ILE n 
1 680 LEU n 
1 681 GLY n 
1 682 HIS n 
1 683 LYS n 
1 684 LEU n 
1 685 GLU n 
1 686 TYR n 
1 687 ASN n 
1 688 TYR n 
1 689 ASN n 
1 690 SER n 
1 691 HIS n 
1 692 ASN n 
1 693 VAL n 
1 694 TYR n 
1 695 ILE n 
1 696 MET n 
1 697 ALA n 
1 698 ASP n 
1 699 LYS n 
1 700 GLN n 
1 701 LYS n 
1 702 ASN n 
1 703 GLY n 
1 704 ILE n 
1 705 LYS n 
1 706 VAL n 
1 707 ASN n 
1 708 PHE n 
1 709 LYS n 
1 710 ILE n 
1 711 ARG n 
1 712 HIS n 
1 713 ASN n 
1 714 ILE n 
1 715 GLU n 
1 716 ASP n 
1 717 GLY n 
1 718 SER n 
1 719 VAL n 
1 720 GLN n 
1 721 LEU n 
1 722 ALA n 
1 723 ASP n 
1 724 HIS n 
1 725 TYR n 
1 726 GLN n 
1 727 GLN n 
1 728 ASN n 
1 729 THR n 
1 730 PRO n 
1 731 ILE n 
1 732 GLY n 
1 733 ASP n 
1 734 GLY n 
1 735 PRO n 
1 736 VAL n 
1 737 LEU n 
1 738 LEU n 
1 739 PRO n 
1 740 ASP n 
1 741 ASN n 
1 742 HIS n 
1 743 TYR n 
1 744 LEU n 
1 745 SER n 
1 746 THR n 
1 747 GLN n 
1 748 SER n 
1 749 LYS n 
1 750 LEU n 
1 751 SER n 
1 752 LYS n 
1 753 ASP n 
1 754 PRO n 
1 755 ASN n 
1 756 GLU n 
1 757 LYS n 
1 758 ARG n 
1 759 ASP n 
1 760 HIS n 
1 761 MET n 
1 762 VAL n 
1 763 LEU n 
1 764 LEU n 
1 765 GLU n 
1 766 PHE n 
1 767 VAL n 
1 768 THR n 
1 769 ALA n 
1 770 ALA n 
1 771 GLY n 
1 772 ILE n 
1 773 THR n 
1 774 LEU n 
1 775 GLY n 
1 776 MET n 
1 777 ASP n 
1 778 GLU n 
1 779 LEU n 
1 780 TYR n 
1 781 LYS n 
1 782 SER n 
1 783 GLY n 
1 784 LEU n 
1 785 ARG n 
1 786 SER n 
1 787 HIS n 
1 788 HIS n 
1 789 HIS n 
1 790 HIS n 
1 791 HIS n 
1 792 HIS n 
1 793 HIS n 
1 794 HIS n 
2 1   MET n 
2 2   ALA n 
2 3   SER n 
2 4   ASN n 
2 5   ASN n 
2 6   THR n 
2 7   ALA n 
2 8   SER n 
2 9   ILE n 
2 10  ALA n 
2 11  GLN n 
2 12  ALA n 
2 13  ARG n 
2 14  LYS n 
2 15  LEU n 
2 16  VAL n 
2 17  GLU n 
2 18  GLN n 
2 19  LEU n 
2 20  LYS n 
2 21  MET n 
2 22  GLU n 
2 23  ALA n 
2 24  ASN n 
2 25  ILE n 
2 26  ASP n 
2 27  ARG n 
2 28  ILE n 
2 29  LYS n 
2 30  VAL n 
2 31  SER n 
2 32  LYS n 
2 33  ALA n 
2 34  ALA n 
2 35  ALA n 
2 36  ASP n 
2 37  LEU n 
2 38  MET n 
2 39  ALA n 
2 40  TYR n 
2 41  CYS n 
2 42  GLU n 
2 43  ALA n 
2 44  HIS n 
2 45  ALA n 
2 46  LYS n 
2 47  GLU n 
2 48  ASP n 
2 49  PRO n 
2 50  LEU n 
2 51  LEU n 
2 52  THR n 
2 53  PRO n 
2 54  VAL n 
2 55  PRO n 
2 56  ALA n 
2 57  SER n 
2 58  GLU n 
2 59  ASN n 
2 60  PRO n 
2 61  PHE n 
2 62  ARG n 
2 63  GLU n 
2 64  LYS n 
2 65  LYS n 
2 66  PHE n 
2 67  PHE n 
2 68  CYS n 
2 69  ALA n 
2 70  ILE n 
2 71  LEU n 
2 72  GLY n 
2 73  SER n 
2 74  ALA n 
2 75  GLY n 
2 76  SER n 
2 77  ALA n 
2 78  GLY n 
2 79  SER n 
2 80  ALA n 
2 81  MET n 
2 82  CYS n 
2 83  THR n 
2 84  LEU n 
2 85  SER n 
2 86  ALA n 
2 87  GLU n 
2 88  ASP n 
2 89  LYS n 
2 90  ALA n 
2 91  ALA n 
2 92  VAL n 
2 93  GLU n 
2 94  ARG n 
2 95  SER n 
2 96  LYS n 
2 97  MET n 
2 98  ILE n 
2 99  ASP n 
2 100 ARG n 
2 101 ASN n 
2 102 LEU n 
2 103 ARG n 
2 104 GLU n 
2 105 ASP n 
2 106 GLY n 
2 107 GLU n 
2 108 LYS n 
2 109 ALA n 
2 110 ALA n 
2 111 ARG n 
2 112 GLU n 
2 113 VAL n 
2 114 LYS n 
2 115 LEU n 
2 116 LEU n 
2 117 LEU n 
2 118 LEU n 
2 119 GLY n 
2 120 ALA n 
2 121 GLY n 
2 122 GLU n 
2 123 SER n 
2 124 GLY n 
2 125 LYS n 
2 126 SER n 
2 127 THR n 
2 128 ILE n 
2 129 VAL n 
2 130 LYS n 
2 131 GLN n 
2 132 MET n 
2 133 LYS n 
2 134 ILE n 
2 135 ILE n 
2 136 HIS n 
2 137 GLU n 
2 138 ALA n 
2 139 GLY n 
2 140 TYR n 
2 141 SER n 
2 142 GLU n 
2 143 GLU n 
2 144 GLU n 
2 145 CYS n 
2 146 LYS n 
2 147 GLN n 
2 148 TYR n 
2 149 LYS n 
2 150 ALA n 
2 151 VAL n 
2 152 VAL n 
2 153 TYR n 
2 154 SER n 
2 155 ASN n 
2 156 THR n 
2 157 ILE n 
2 158 GLN n 
2 159 SER n 
2 160 ILE n 
2 161 ILE n 
2 162 ALA n 
2 163 ILE n 
2 164 ILE n 
2 165 ARG n 
2 166 ALA n 
2 167 MET n 
2 168 GLY n 
2 169 ARG n 
2 170 LEU n 
2 171 LYS n 
2 172 ILE n 
2 173 ASP n 
2 174 PHE n 
2 175 GLY n 
2 176 ASP n 
2 177 SER n 
2 178 ALA n 
2 179 ARG n 
2 180 ALA n 
2 181 ASP n 
2 182 ASP n 
2 183 ALA n 
2 184 ARG n 
2 185 GLN n 
2 186 LEU n 
2 187 PHE n 
2 188 VAL n 
2 189 LEU n 
2 190 ALA n 
2 191 GLY n 
2 192 ALA n 
2 193 ALA n 
2 194 GLU n 
2 195 GLU n 
2 196 GLY n 
2 197 PHE n 
2 198 MET n 
2 199 THR n 
2 200 ALA n 
2 201 GLU n 
2 202 LEU n 
2 203 ALA n 
2 204 GLY n 
2 205 VAL n 
2 206 ILE n 
2 207 LYS n 
2 208 ARG n 
2 209 LEU n 
2 210 TRP n 
2 211 LYS n 
2 212 ASP n 
2 213 SER n 
2 214 GLY n 
2 215 VAL n 
2 216 GLN n 
2 217 ALA n 
2 218 CYS n 
2 219 PHE n 
2 220 ASN n 
2 221 ARG n 
2 222 SER n 
2 223 ARG n 
2 224 GLU n 
2 225 TYR n 
2 226 GLN n 
2 227 LEU n 
2 228 ASN n 
2 229 ASP n 
2 230 SER n 
2 231 ALA n 
2 232 ALA n 
2 233 TYR n 
2 234 TYR n 
2 235 LEU n 
2 236 ASN n 
2 237 ASP n 
2 238 LEU n 
2 239 ASP n 
2 240 ARG n 
2 241 ILE n 
2 242 ALA n 
2 243 GLN n 
2 244 PRO n 
2 245 ASN n 
2 246 TYR n 
2 247 ILE n 
2 248 PRO n 
2 249 THR n 
2 250 GLN n 
2 251 GLN n 
2 252 ASP n 
2 253 VAL n 
2 254 LEU n 
2 255 ARG n 
2 256 THR n 
2 257 ARG n 
2 258 VAL n 
2 259 LYS n 
2 260 THR n 
2 261 THR n 
2 262 GLY n 
2 263 ILE n 
2 264 VAL n 
2 265 GLU n 
2 266 THR n 
2 267 HIS n 
2 268 PHE n 
2 269 THR n 
2 270 PHE n 
2 271 LYS n 
2 272 ASP n 
2 273 LEU n 
2 274 HIS n 
2 275 PHE n 
2 276 LYS n 
2 277 MET n 
2 278 PHE n 
2 279 ASP n 
2 280 VAL n 
2 281 GLY n 
2 282 GLY n 
2 283 GLN n 
2 284 ARG n 
2 285 SER n 
2 286 GLU n 
2 287 ARG n 
2 288 LYS n 
2 289 LYS n 
2 290 TRP n 
2 291 ILE n 
2 292 HIS n 
2 293 CYS n 
2 294 PHE n 
2 295 GLU n 
2 296 GLY n 
2 297 VAL n 
2 298 THR n 
2 299 ALA n 
2 300 ILE n 
2 301 ILE n 
2 302 PHE n 
2 303 CYS n 
2 304 VAL n 
2 305 ALA n 
2 306 LEU n 
2 307 SER n 
2 308 ASP n 
2 309 TYR n 
2 310 ASP n 
2 311 LEU n 
2 312 VAL n 
2 313 LEU n 
2 314 ALA n 
2 315 GLU n 
2 316 ASP n 
2 317 GLU n 
2 318 GLU n 
2 319 MET n 
2 320 ASN n 
2 321 ARG n 
2 322 MET n 
2 323 HIS n 
2 324 GLU n 
2 325 SER n 
2 326 MET n 
2 327 LYS n 
2 328 LEU n 
2 329 PHE n 
2 330 ASP n 
2 331 SER n 
2 332 ILE n 
2 333 CYS n 
2 334 ASN n 
2 335 ASN n 
2 336 LYS n 
2 337 TRP n 
2 338 PHE n 
2 339 THR n 
2 340 ASP n 
2 341 THR n 
2 342 SER n 
2 343 ILE n 
2 344 ILE n 
2 345 LEU n 
2 346 PHE n 
2 347 LEU n 
2 348 ASN n 
2 349 LYS n 
2 350 LYS n 
2 351 ASP n 
2 352 LEU n 
2 353 PHE n 
2 354 GLU n 
2 355 GLU n 
2 356 LYS n 
2 357 ILE n 
2 358 LYS n 
2 359 LYS n 
2 360 SER n 
2 361 PRO n 
2 362 LEU n 
2 363 THR n 
2 364 ILE n 
2 365 CYS n 
2 366 TYR n 
2 367 PRO n 
2 368 GLU n 
2 369 TYR n 
2 370 ALA n 
2 371 GLY n 
2 372 SER n 
2 373 ASN n 
2 374 THR n 
2 375 TYR n 
2 376 GLU n 
2 377 GLU n 
2 378 ALA n 
2 379 ALA n 
2 380 ALA n 
2 381 TYR n 
2 382 ILE n 
2 383 GLN n 
2 384 CYS n 
2 385 GLN n 
2 386 PHE n 
2 387 GLU n 
2 388 ASP n 
2 389 LEU n 
2 390 ASN n 
2 391 LYS n 
2 392 ARG n 
2 393 LYS n 
2 394 ASP n 
2 395 THR n 
2 396 LYS n 
2 397 GLU n 
2 398 ILE n 
2 399 TYR n 
2 400 THR n 
2 401 HIS n 
2 402 PHE n 
2 403 THR n 
2 404 CYS n 
2 405 ALA n 
2 406 THR n 
2 407 ASP n 
2 408 THR n 
2 409 LYS n 
2 410 ASN n 
2 411 VAL n 
2 412 GLN n 
2 413 PHE n 
2 414 VAL n 
2 415 PHE n 
2 416 ASP n 
2 417 ALA n 
2 418 VAL n 
2 419 THR n 
2 420 ASP n 
2 421 VAL n 
2 422 ILE n 
2 423 ILE n 
2 424 LYS n 
2 425 ASN n 
2 426 ASN n 
2 427 LEU n 
2 428 LYS n 
2 429 ASP n 
2 430 CYS n 
2 431 GLY n 
2 432 LEU n 
2 433 PHE n 
3 1   MET n 
3 2   GLY n 
3 3   SER n 
3 4   LEU n 
3 5   LEU n 
3 6   GLN n 
3 7   SER n 
3 8   GLU n 
3 9   LEU n 
3 10  ASP n 
3 11  GLN n 
3 12  LEU n 
3 13  ARG n 
3 14  GLN n 
3 15  GLU n 
3 16  ALA n 
3 17  GLU n 
3 18  GLN n 
3 19  LEU n 
3 20  LYS n 
3 21  ASN n 
3 22  GLN n 
3 23  ILE n 
3 24  ARG n 
3 25  ASP n 
3 26  ALA n 
3 27  ARG n 
3 28  LYS n 
3 29  ALA n 
3 30  CYS n 
3 31  ALA n 
3 32  ASP n 
3 33  ALA n 
3 34  THR n 
3 35  LEU n 
3 36  SER n 
3 37  GLN n 
3 38  ILE n 
3 39  THR n 
3 40  ASN n 
3 41  ASN n 
3 42  ILE n 
3 43  ASP n 
3 44  PRO n 
3 45  VAL n 
3 46  GLY n 
3 47  ARG n 
3 48  ILE n 
3 49  GLN n 
3 50  MET n 
3 51  ARG n 
3 52  THR n 
3 53  ARG n 
3 54  ARG n 
3 55  THR n 
3 56  LEU n 
3 57  ARG n 
3 58  GLY n 
3 59  HIS n 
3 60  LEU n 
3 61  ALA n 
3 62  LYS n 
3 63  ILE n 
3 64  TYR n 
3 65  ALA n 
3 66  MET n 
3 67  HIS n 
3 68  TRP n 
3 69  GLY n 
3 70  THR n 
3 71  ASP n 
3 72  SER n 
3 73  ARG n 
3 74  LEU n 
3 75  LEU n 
3 76  VAL n 
3 77  SER n 
3 78  ALA n 
3 79  SER n 
3 80  GLN n 
3 81  ASP n 
3 82  GLY n 
3 83  LYS n 
3 84  LEU n 
3 85  ILE n 
3 86  ILE n 
3 87  TRP n 
3 88  ASP n 
3 89  SER n 
3 90  TYR n 
3 91  THR n 
3 92  THR n 
3 93  ASN n 
3 94  LYS n 
3 95  VAL n 
3 96  HIS n 
3 97  ALA n 
3 98  ILE n 
3 99  PRO n 
3 100 LEU n 
3 101 ARG n 
3 102 SER n 
3 103 SER n 
3 104 TRP n 
3 105 VAL n 
3 106 MET n 
3 107 THR n 
3 108 CYS n 
3 109 ALA n 
3 110 TYR n 
3 111 ALA n 
3 112 PRO n 
3 113 SER n 
3 114 GLY n 
3 115 ASN n 
3 116 TYR n 
3 117 VAL n 
3 118 ALA n 
3 119 CYS n 
3 120 GLY n 
3 121 GLY n 
3 122 LEU n 
3 123 ASP n 
3 124 ASN n 
3 125 ILE n 
3 126 CYS n 
3 127 SER n 
3 128 ILE n 
3 129 TYR n 
3 130 ASN n 
3 131 LEU n 
3 132 LYS n 
3 133 THR n 
3 134 ARG n 
3 135 GLU n 
3 136 GLY n 
3 137 ASN n 
3 138 VAL n 
3 139 ARG n 
3 140 VAL n 
3 141 SER n 
3 142 ARG n 
3 143 GLU n 
3 144 LEU n 
3 145 ALA n 
3 146 GLY n 
3 147 HIS n 
3 148 THR n 
3 149 GLY n 
3 150 TYR n 
3 151 LEU n 
3 152 SER n 
3 153 CYS n 
3 154 CYS n 
3 155 ARG n 
3 156 PHE n 
3 157 LEU n 
3 158 ASP n 
3 159 ASP n 
3 160 ASN n 
3 161 GLN n 
3 162 ILE n 
3 163 VAL n 
3 164 THR n 
3 165 SER n 
3 166 SER n 
3 167 GLY n 
3 168 ASP n 
3 169 THR n 
3 170 THR n 
3 171 CYS n 
3 172 ALA n 
3 173 LEU n 
3 174 TRP n 
3 175 ASP n 
3 176 ILE n 
3 177 GLU n 
3 178 THR n 
3 179 GLY n 
3 180 GLN n 
3 181 GLN n 
3 182 THR n 
3 183 THR n 
3 184 THR n 
3 185 PHE n 
3 186 THR n 
3 187 GLY n 
3 188 HIS n 
3 189 THR n 
3 190 GLY n 
3 191 ASP n 
3 192 VAL n 
3 193 MET n 
3 194 SER n 
3 195 LEU n 
3 196 SER n 
3 197 LEU n 
3 198 ALA n 
3 199 PRO n 
3 200 ASP n 
3 201 THR n 
3 202 ARG n 
3 203 LEU n 
3 204 PHE n 
3 205 VAL n 
3 206 SER n 
3 207 GLY n 
3 208 ALA n 
3 209 CYS n 
3 210 ASP n 
3 211 ALA n 
3 212 SER n 
3 213 ALA n 
3 214 LYS n 
3 215 LEU n 
3 216 TRP n 
3 217 ASP n 
3 218 VAL n 
3 219 ARG n 
3 220 GLU n 
3 221 GLY n 
3 222 MET n 
3 223 CYS n 
3 224 ARG n 
3 225 GLN n 
3 226 THR n 
3 227 PHE n 
3 228 THR n 
3 229 GLY n 
3 230 HIS n 
3 231 GLU n 
3 232 SER n 
3 233 ASP n 
3 234 ILE n 
3 235 ASN n 
3 236 ALA n 
3 237 ILE n 
3 238 CYS n 
3 239 PHE n 
3 240 PHE n 
3 241 PRO n 
3 242 ASN n 
3 243 GLY n 
3 244 ASN n 
3 245 ALA n 
3 246 PHE n 
3 247 ALA n 
3 248 THR n 
3 249 GLY n 
3 250 SER n 
3 251 ASP n 
3 252 ASP n 
3 253 ALA n 
3 254 THR n 
3 255 CYS n 
3 256 ARG n 
3 257 LEU n 
3 258 PHE n 
3 259 ASP n 
3 260 LEU n 
3 261 ARG n 
3 262 ALA n 
3 263 ASP n 
3 264 GLN n 
3 265 GLU n 
3 266 LEU n 
3 267 MET n 
3 268 THR n 
3 269 TYR n 
3 270 SER n 
3 271 HIS n 
3 272 ASP n 
3 273 ASN n 
3 274 ILE n 
3 275 ILE n 
3 276 CYS n 
3 277 GLY n 
3 278 ILE n 
3 279 THR n 
3 280 SER n 
3 281 VAL n 
3 282 SER n 
3 283 PHE n 
3 284 SER n 
3 285 LYS n 
3 286 SER n 
3 287 GLY n 
3 288 ARG n 
3 289 LEU n 
3 290 LEU n 
3 291 LEU n 
3 292 ALA n 
3 293 GLY n 
3 294 TYR n 
3 295 ASP n 
3 296 ASP n 
3 297 PHE n 
3 298 ASN n 
3 299 CYS n 
3 300 ASN n 
3 301 VAL n 
3 302 TRP n 
3 303 ASP n 
3 304 ALA n 
3 305 LEU n 
3 306 LYS n 
3 307 ALA n 
3 308 ASP n 
3 309 ARG n 
3 310 ALA n 
3 311 GLY n 
3 312 VAL n 
3 313 LEU n 
3 314 ALA n 
3 315 GLY n 
3 316 HIS n 
3 317 ASP n 
3 318 ASN n 
3 319 ARG n 
3 320 VAL n 
3 321 SER n 
3 322 CYS n 
3 323 LEU n 
3 324 GLY n 
3 325 VAL n 
3 326 THR n 
3 327 ASP n 
3 328 ASP n 
3 329 GLY n 
3 330 MET n 
3 331 ALA n 
3 332 VAL n 
3 333 ALA n 
3 334 THR n 
3 335 GLY n 
3 336 SER n 
3 337 TRP n 
3 338 ASP n 
3 339 SER n 
3 340 PHE n 
3 341 LEU n 
3 342 LYS n 
3 343 ILE n 
3 344 TRP n 
3 345 ASN n 
3 346 GLY n 
3 347 ALA n 
3 348 SER n 
3 349 GLY n 
3 350 GLY n 
3 351 GLY n 
3 352 SER n 
3 353 GLY n 
3 354 GLY n 
3 355 ASN n 
3 356 SER n 
3 357 GLY n 
3 358 SER n 
3 359 SER n 
3 360 GLY n 
3 361 GLY n 
3 362 SER n 
3 363 SER n 
3 364 GLY n 
3 365 VAL n 
3 366 SER n 
3 367 GLY n 
3 368 TRP n 
3 369 ARG n 
3 370 LEU n 
3 371 PHE n 
3 372 LYS n 
3 373 LYS n 
3 374 ILE n 
3 375 SER n 
4 1   ASP n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   VAL n 
4 6   GLU n 
4 7   SER n 
4 8   GLY n 
4 9   GLY n 
4 10  GLY n 
4 11  LEU n 
4 12  VAL n 
4 13  GLN n 
4 14  PRO n 
4 15  GLY n 
4 16  GLY n 
4 17  SER n 
4 18  ARG n 
4 19  LYS n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  SER n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  PHE n 
4 28  ALA n 
4 29  PHE n 
4 30  SER n 
4 31  SER n 
4 32  PHE n 
4 33  GLY n 
4 34  MET n 
4 35  HIS n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  GLN n 
4 40  ALA n 
4 41  PRO n 
4 42  GLU n 
4 43  LYS n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  TRP n 
4 48  VAL n 
4 49  ALA n 
4 50  TYR n 
4 51  ILE n 
4 52  SER n 
4 53  SER n 
4 54  GLY n 
4 55  SER n 
4 56  GLY n 
4 57  THR n 
4 58  ILE n 
4 59  TYR n 
4 60  TYR n 
4 61  ALA n 
4 62  ASP n 
4 63  THR n 
4 64  VAL n 
4 65  LYS n 
4 66  GLY n 
4 67  ARG n 
4 68  PHE n 
4 69  THR n 
4 70  ILE n 
4 71  SER n 
4 72  ARG n 
4 73  ASP n 
4 74  ASP n 
4 75  PRO n 
4 76  LYS n 
4 77  ASN n 
4 78  THR n 
4 79  LEU n 
4 80  PHE n 
4 81  LEU n 
4 82  GLN n 
4 83  MET n 
4 84  THR n 
4 85  SER n 
4 86  LEU n 
4 87  ARG n 
4 88  SER n 
4 89  GLU n 
4 90  ASP n 
4 91  THR n 
4 92  ALA n 
4 93  MET n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  VAL n 
4 98  ARG n 
4 99  SER n 
4 100 ILE n 
4 101 TYR n 
4 102 TYR n 
4 103 TYR n 
4 104 GLY n 
4 105 SER n 
4 106 SER n 
4 107 PRO n 
4 108 PHE n 
4 109 ASP n 
4 110 PHE n 
4 111 TRP n 
4 112 GLY n 
4 113 GLN n 
4 114 GLY n 
4 115 THR n 
4 116 THR n 
4 117 LEU n 
4 118 THR n 
4 119 VAL n 
4 120 SER n 
4 121 SER n 
4 122 GLY n 
4 123 GLY n 
4 124 GLY n 
4 125 GLY n 
4 126 SER n 
4 127 GLY n 
4 128 GLY n 
4 129 GLY n 
4 130 GLY n 
4 131 SER n 
4 132 GLY n 
4 133 GLY n 
4 134 GLY n 
4 135 GLY n 
4 136 SER n 
4 137 ASP n 
4 138 ILE n 
4 139 VAL n 
4 140 MET n 
4 141 THR n 
4 142 GLN n 
4 143 ALA n 
4 144 THR n 
4 145 SER n 
4 146 SER n 
4 147 VAL n 
4 148 PRO n 
4 149 VAL n 
4 150 THR n 
4 151 PRO n 
4 152 GLY n 
4 153 GLU n 
4 154 SER n 
4 155 VAL n 
4 156 SER n 
4 157 ILE n 
4 158 SER n 
4 159 CYS n 
4 160 ARG n 
4 161 SER n 
4 162 SER n 
4 163 LYS n 
4 164 SER n 
4 165 LEU n 
4 166 LEU n 
4 167 HIS n 
4 168 SER n 
4 169 ASN n 
4 170 GLY n 
4 171 ASN n 
4 172 THR n 
4 173 TYR n 
4 174 LEU n 
4 175 TYR n 
4 176 TRP n 
4 177 PHE n 
4 178 LEU n 
4 179 GLN n 
4 180 ARG n 
4 181 PRO n 
4 182 GLY n 
4 183 GLN n 
4 184 SER n 
4 185 PRO n 
4 186 GLN n 
4 187 LEU n 
4 188 LEU n 
4 189 ILE n 
4 190 TYR n 
4 191 ARG n 
4 192 MET n 
4 193 SER n 
4 194 ASN n 
4 195 LEU n 
4 196 ALA n 
4 197 SER n 
4 198 GLY n 
4 199 VAL n 
4 200 PRO n 
4 201 ASP n 
4 202 ARG n 
4 203 PHE n 
4 204 SER n 
4 205 GLY n 
4 206 SER n 
4 207 GLY n 
4 208 SER n 
4 209 GLY n 
4 210 THR n 
4 211 ALA n 
4 212 PHE n 
4 213 THR n 
4 214 LEU n 
4 215 THR n 
4 216 ILE n 
4 217 SER n 
4 218 ARG n 
4 219 LEU n 
4 220 GLU n 
4 221 ALA n 
4 222 GLU n 
4 223 ASP n 
4 224 VAL n 
4 225 GLY n 
4 226 VAL n 
4 227 TYR n 
4 228 TYR n 
4 229 CYS n 
4 230 MET n 
4 231 GLN n 
4 232 HIS n 
4 233 LEU n 
4 234 GLU n 
4 235 TYR n 
4 236 PRO n 
4 237 LEU n 
4 238 THR n 
4 239 PHE n 
4 240 GLY n 
4 241 ALA n 
4 242 GLY n 
4 243 THR n 
4 244 LYS n 
4 245 LEU n 
4 246 GLU n 
4 247 LEU n 
4 248 LYS n 
4 249 ALA n 
4 250 ALA n 
4 251 ALA n 
4 252 ALA n 
4 253 SER n 
4 254 SER n 
4 255 GLU n 
4 256 ASP n 
4 257 LEU n 
4 258 TYR n 
4 259 PHE n 
4 260 GLN n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   16  ?           ? HA     ? ? ? ? ? ? 'Influenza A virus (A/Victoria/3/1975(H3N2))' 392809 ? ? 
? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 17  356 sheep       ? ADORA3 ? ? ? ? ? ? 'Ovis aries'                                  9940   ? ? 
? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
1 3 sample 'Biological sequence' 357 514 ?           ? ?      ? ? ? ? ? ? 'Ovis aries'                                  9940   ? ? 
? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
1 4 sample 'Biological sequence' 515 794 ?           ? ?      ? ? ? ? ? ? 'Ovis aries'                                  9940   ? ? 
? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   71  human       ? GNG2   ? ? ? ? ? ? 'Homo sapiens'                                9606   ? ? 
? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
2 2 sample 'Biological sequence' 72  433 human       ? GNAI1  ? ? ? ? ? ? 'Homo sapiens'                                9606   ? ? 
? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   375 'black rat' ? GNB1   ? ? ? ? ? ? 'Rattus rattus'                               10117  ? ? 
? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   260 ?           ? ?      ? ? ? ? ? ? 'Mus musculus'                                10090  ? ? 
? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                            ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                           ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                         ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                    ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                           ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                          ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                    ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                            ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                          ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                         ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                            ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                             ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                         ? 'C5 H11 N O2 S'  149.211 
NEC non-polymer         . 
;N-ETHYL-5'-CARBOXAMIDO ADENOSINE
;
? 'C12 H16 N6 O4'  308.293 
PHE 'L-peptide linking' y PHENYLALANINE                      ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                            ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                             ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                          ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                         ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                           ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                             ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -24 ?   ?   ?   R . n 
A 1 2   LYS 2   -23 ?   ?   ?   R . n 
A 1 3   THR 3   -22 ?   ?   ?   R . n 
A 1 4   ILE 4   -21 ?   ?   ?   R . n 
A 1 5   ILE 5   -20 ?   ?   ?   R . n 
A 1 6   ALA 6   -19 ?   ?   ?   R . n 
A 1 7   LEU 7   -18 ?   ?   ?   R . n 
A 1 8   SER 8   -17 ?   ?   ?   R . n 
A 1 9   TYR 9   -16 ?   ?   ?   R . n 
A 1 10  ILE 10  -15 ?   ?   ?   R . n 
A 1 11  PHE 11  -14 ?   ?   ?   R . n 
A 1 12  CYS 12  -13 ?   ?   ?   R . n 
A 1 13  LEU 13  -12 ?   ?   ?   R . n 
A 1 14  VAL 14  -11 ?   ?   ?   R . n 
A 1 15  PHE 15  -10 ?   ?   ?   R . n 
A 1 16  ALA 16  -9  ?   ?   ?   R . n 
A 1 17  ASP 17  -8  ?   ?   ?   R . n 
A 1 18  TYR 18  -7  ?   ?   ?   R . n 
A 1 19  LYS 19  -6  ?   ?   ?   R . n 
A 1 20  ASP 20  -5  ?   ?   ?   R . n 
A 1 21  ASP 21  -4  ?   ?   ?   R . n 
A 1 22  ASP 22  -3  ?   ?   ?   R . n 
A 1 23  ASP 23  -2  ?   ?   ?   R . n 
A 1 24  ALA 24  -1  ?   ?   ?   R . n 
A 1 25  MET 25  0   ?   ?   ?   R . n 
A 1 26  GLY 26  1   ?   ?   ?   R . n 
A 1 27  PRO 27  2   ?   ?   ?   R . n 
A 1 28  VAL 28  3   ?   ?   ?   R . n 
A 1 29  ASN 29  4   ?   ?   ?   R . n 
A 1 30  SER 30  5   ?   ?   ?   R . n 
A 1 31  THR 31  6   ?   ?   ?   R . n 
A 1 32  ALA 32  7   ?   ?   ?   R . n 
A 1 33  VAL 33  8   ?   ?   ?   R . n 
A 1 34  SER 34  9   9   SER SER R . n 
A 1 35  TRP 35  10  10  TRP TRP R . n 
A 1 36  THR 36  11  11  THR THR R . n 
A 1 37  SER 37  12  12  SER SER R . n 
A 1 38  VAL 38  13  13  VAL VAL R . n 
A 1 39  THR 39  14  14  THR THR R . n 
A 1 40  TYR 40  15  15  TYR TYR R . n 
A 1 41  ILE 41  16  16  ILE ILE R . n 
A 1 42  THR 42  17  17  THR THR R . n 
A 1 43  VAL 43  18  18  VAL VAL R . n 
A 1 44  GLU 44  19  19  GLU GLU R . n 
A 1 45  ILE 45  20  20  ILE ILE R . n 
A 1 46  LEU 46  21  21  LEU LEU R . n 
A 1 47  ILE 47  22  22  ILE ILE R . n 
A 1 48  GLY 48  23  23  GLY GLY R . n 
A 1 49  LEU 49  24  24  LEU LEU R . n 
A 1 50  CYS 50  25  25  CYS CYS R . n 
A 1 51  ALA 51  26  26  ALA ALA R . n 
A 1 52  ILE 52  27  27  ILE ILE R . n 
A 1 53  VAL 53  28  28  VAL VAL R . n 
A 1 54  GLY 54  29  29  GLY GLY R . n 
A 1 55  ASN 55  30  30  ASN ASN R . n 
A 1 56  VAL 56  31  31  VAL VAL R . n 
A 1 57  LEU 57  32  32  LEU LEU R . n 
A 1 58  VAL 58  33  33  VAL VAL R . n 
A 1 59  ILE 59  34  34  ILE ILE R . n 
A 1 60  TRP 60  35  35  TRP TRP R . n 
A 1 61  VAL 61  36  36  VAL VAL R . n 
A 1 62  VAL 62  37  37  VAL VAL R . n 
A 1 63  LYS 63  38  38  LYS LYS R . n 
A 1 64  LEU 64  39  39  LEU LEU R . n 
A 1 65  ASN 65  40  40  ASN ASN R . n 
A 1 66  PRO 66  41  41  PRO PRO R . n 
A 1 67  SER 67  42  42  SER SER R . n 
A 1 68  LEU 68  43  43  LEU LEU R . n 
A 1 69  GLN 69  44  44  GLN GLN R . n 
A 1 70  THR 70  45  45  THR THR R . n 
A 1 71  THR 71  46  46  THR THR R . n 
A 1 72  THR 72  47  47  THR THR R . n 
A 1 73  PHE 73  48  48  PHE PHE R . n 
A 1 74  TYR 74  49  49  TYR TYR R . n 
A 1 75  PHE 75  50  50  PHE PHE R . n 
A 1 76  ILE 76  51  51  ILE ILE R . n 
A 1 77  VAL 77  52  52  VAL VAL R . n 
A 1 78  SER 78  53  53  SER SER R . n 
A 1 79  LEU 79  54  54  LEU LEU R . n 
A 1 80  ALA 80  55  55  ALA ALA R . n 
A 1 81  LEU 81  56  56  LEU LEU R . n 
A 1 82  ALA 82  57  57  ALA ALA R . n 
A 1 83  ASP 83  58  58  ASP ASP R . n 
A 1 84  ILE 84  59  59  ILE ILE R . n 
A 1 85  ALA 85  60  60  ALA ALA R . n 
A 1 86  VAL 86  61  61  VAL VAL R . n 
A 1 87  GLY 87  62  62  GLY GLY R . n 
A 1 88  VAL 88  63  63  VAL VAL R . n 
A 1 89  LEU 89  64  64  LEU LEU R . n 
A 1 90  VAL 90  65  65  VAL VAL R . n 
A 1 91  MET 91  66  66  MET MET R . n 
A 1 92  PRO 92  67  67  PRO PRO R . n 
A 1 93  LEU 93  68  68  LEU LEU R . n 
A 1 94  ALA 94  69  69  ALA ALA R . n 
A 1 95  ILE 95  70  70  ILE ILE R . n 
A 1 96  VAL 96  71  71  VAL VAL R . n 
A 1 97  ILE 97  72  72  ILE ILE R . n 
A 1 98  SER 98  73  73  SER SER R . n 
A 1 99  LEU 99  74  74  LEU LEU R . n 
A 1 100 GLY 100 75  75  GLY GLY R . n 
A 1 101 VAL 101 76  76  VAL VAL R . n 
A 1 102 THR 102 77  77  THR THR R . n 
A 1 103 ILE 103 78  78  ILE ILE R . n 
A 1 104 HIS 104 79  79  HIS HIS R . n 
A 1 105 PHE 105 80  80  PHE PHE R . n 
A 1 106 TYR 106 81  81  TYR TYR R . n 
A 1 107 SER 107 82  82  SER SER R . n 
A 1 108 CYS 108 83  83  CYS CYS R . n 
A 1 109 LEU 109 84  84  LEU LEU R . n 
A 1 110 PHE 110 85  85  PHE PHE R . n 
A 1 111 MET 111 86  86  MET MET R . n 
A 1 112 THR 112 87  87  THR THR R . n 
A 1 113 CYS 113 88  88  CYS CYS R . n 
A 1 114 LEU 114 89  89  LEU LEU R . n 
A 1 115 MET 115 90  90  MET MET R . n 
A 1 116 LEU 116 91  91  LEU LEU R . n 
A 1 117 ILE 117 92  92  ILE ILE R . n 
A 1 118 PHE 118 93  93  PHE PHE R . n 
A 1 119 THR 119 94  94  THR THR R . n 
A 1 120 HIS 120 95  95  HIS HIS R . n 
A 1 121 ALA 121 96  96  ALA ALA R . n 
A 1 122 SER 122 97  97  SER SER R . n 
A 1 123 ILE 123 98  98  ILE ILE R . n 
A 1 124 MET 124 99  99  MET MET R . n 
A 1 125 SER 125 100 100 SER SER R . n 
A 1 126 LEU 126 101 101 LEU LEU R . n 
A 1 127 LEU 127 102 102 LEU LEU R . n 
A 1 128 ALA 128 103 103 ALA ALA R . n 
A 1 129 ILE 129 104 104 ILE ILE R . n 
A 1 130 ALA 130 105 105 ALA ALA R . n 
A 1 131 VAL 131 106 106 VAL VAL R . n 
A 1 132 ASP 132 107 107 ASP ASP R . n 
A 1 133 ARG 133 108 108 ARG ARG R . n 
A 1 134 TYR 134 109 109 TYR TYR R . n 
A 1 135 LEU 135 110 110 LEU LEU R . n 
A 1 136 ARG 136 111 111 ARG ARG R . n 
A 1 137 VAL 137 112 112 VAL VAL R . n 
A 1 138 LYS 138 113 113 LYS LYS R . n 
A 1 139 LEU 139 114 114 LEU LEU R . n 
A 1 140 THR 140 115 115 THR THR R . n 
A 1 141 VAL 141 116 116 VAL VAL R . n 
A 1 142 ARG 142 117 117 ARG ARG R . n 
A 1 143 TYR 143 118 118 TYR TYR R . n 
A 1 144 ARG 144 119 119 ARG ARG R . n 
A 1 145 ARG 145 120 120 ARG ARG R . n 
A 1 146 VAL 146 121 121 VAL VAL R . n 
A 1 147 THR 147 122 122 THR THR R . n 
A 1 148 THR 148 123 123 THR THR R . n 
A 1 149 GLN 149 124 124 GLN GLN R . n 
A 1 150 ARG 150 125 125 ARG ARG R . n 
A 1 151 ARG 151 126 126 ARG ARG R . n 
A 1 152 ILE 152 127 127 ILE ILE R . n 
A 1 153 TRP 153 128 128 TRP TRP R . n 
A 1 154 LEU 154 129 129 LEU LEU R . n 
A 1 155 ALA 155 130 130 ALA ALA R . n 
A 1 156 LEU 156 131 131 LEU LEU R . n 
A 1 157 GLY 157 132 132 GLY GLY R . n 
A 1 158 LEU 158 133 133 LEU LEU R . n 
A 1 159 CYS 159 134 134 CYS CYS R . n 
A 1 160 TRP 160 135 135 TRP TRP R . n 
A 1 161 LEU 161 136 136 LEU LEU R . n 
A 1 162 VAL 162 137 137 VAL VAL R . n 
A 1 163 SER 163 138 138 SER SER R . n 
A 1 164 PHE 164 139 139 PHE PHE R . n 
A 1 165 LEU 165 140 140 LEU LEU R . n 
A 1 166 VAL 166 141 141 VAL VAL R . n 
A 1 167 GLY 167 142 142 GLY GLY R . n 
A 1 168 LEU 168 143 143 LEU LEU R . n 
A 1 169 THR 169 144 144 THR THR R . n 
A 1 170 PRO 170 145 145 PRO PRO R . n 
A 1 171 MET 171 146 146 MET MET R . n 
A 1 172 PHE 172 147 147 PHE PHE R . n 
A 1 173 GLY 173 148 148 GLY GLY R . n 
A 1 174 TRP 174 149 149 TRP TRP R . n 
A 1 175 ASN 175 150 150 ASN ASN R . n 
A 1 176 MET 176 151 151 MET MET R . n 
A 1 177 LYS 177 152 152 LYS LYS R . n 
A 1 178 LEU 178 153 153 LEU LEU R . n 
A 1 179 SER 179 154 154 SER SER R . n 
A 1 180 SER 180 155 155 SER SER R . n 
A 1 181 ALA 181 156 156 ALA ALA R . n 
A 1 182 ASP 182 157 157 ASP ASP R . n 
A 1 183 GLU 183 158 158 GLU GLU R . n 
A 1 184 ASN 184 159 159 ASN ASN R . n 
A 1 185 LEU 185 160 160 LEU LEU R . n 
A 1 186 THR 186 161 161 THR THR R . n 
A 1 187 PHE 187 162 162 PHE PHE R . n 
A 1 188 LEU 188 163 163 LEU LEU R . n 
A 1 189 PRO 189 164 164 PRO PRO R . n 
A 1 190 CYS 190 165 165 CYS CYS R . n 
A 1 191 ARG 191 166 166 ARG ARG R . n 
A 1 192 PHE 192 167 167 PHE PHE R . n 
A 1 193 ARG 193 168 168 ARG ARG R . n 
A 1 194 SER 194 169 169 SER SER R . n 
A 1 195 VAL 195 170 170 VAL VAL R . n 
A 1 196 MET 196 171 171 MET MET R . n 
A 1 197 ARG 197 172 172 ARG ARG R . n 
A 1 198 MET 198 173 173 MET MET R . n 
A 1 199 ASP 199 174 174 ASP ASP R . n 
A 1 200 TYR 200 175 175 TYR TYR R . n 
A 1 201 MET 201 176 176 MET MET R . n 
A 1 202 VAL 202 177 177 VAL VAL R . n 
A 1 203 TYR 203 178 178 TYR TYR R . n 
A 1 204 PHE 204 179 179 PHE PHE R . n 
A 1 205 SER 205 180 180 SER SER R . n 
A 1 206 PHE 206 181 181 PHE PHE R . n 
A 1 207 PHE 207 182 182 PHE PHE R . n 
A 1 208 LEU 208 183 183 LEU LEU R . n 
A 1 209 TRP 209 184 184 TRP TRP R . n 
A 1 210 ILE 210 185 185 ILE ILE R . n 
A 1 211 LEU 211 186 186 LEU LEU R . n 
A 1 212 VAL 212 187 187 VAL VAL R . n 
A 1 213 PRO 213 188 188 PRO PRO R . n 
A 1 214 LEU 214 189 189 LEU LEU R . n 
A 1 215 VAL 215 190 190 VAL VAL R . n 
A 1 216 VAL 216 191 191 VAL VAL R . n 
A 1 217 MET 217 192 192 MET MET R . n 
A 1 218 CYS 218 193 193 CYS CYS R . n 
A 1 219 ALA 219 194 194 ALA ALA R . n 
A 1 220 ILE 220 195 195 ILE ILE R . n 
A 1 221 TYR 221 196 196 TYR TYR R . n 
A 1 222 PHE 222 197 197 PHE PHE R . n 
A 1 223 ASP 223 198 198 ASP ASP R . n 
A 1 224 ILE 224 199 199 ILE ILE R . n 
A 1 225 PHE 225 200 200 PHE PHE R . n 
A 1 226 TYR 226 201 201 TYR TYR R . n 
A 1 227 ILE 227 202 202 ILE ILE R . n 
A 1 228 ILE 228 203 203 ILE ILE R . n 
A 1 229 ARG 229 204 204 ARG ARG R . n 
A 1 230 ASN 230 205 205 ASN ASN R . n 
A 1 231 ARG 231 206 206 ARG ARG R . n 
A 1 232 LEU 232 207 207 LEU LEU R . n 
A 1 233 SER 233 208 ?   ?   ?   R . n 
A 1 234 GLN 234 209 ?   ?   ?   R . n 
A 1 235 SER 235 210 ?   ?   ?   R . n 
A 1 236 PHE 236 211 ?   ?   ?   R . n 
A 1 237 SER 237 212 ?   ?   ?   R . n 
A 1 238 GLY 238 213 ?   ?   ?   R . n 
A 1 239 SER 239 214 ?   ?   ?   R . n 
A 1 240 ARG 240 215 ?   ?   ?   R . n 
A 1 241 GLU 241 216 ?   ?   ?   R . n 
A 1 242 THR 242 217 ?   ?   ?   R . n 
A 1 243 GLY 243 218 ?   ?   ?   R . n 
A 1 244 ALA 244 219 ?   ?   ?   R . n 
A 1 245 PHE 245 220 ?   ?   ?   R . n 
A 1 246 TYR 246 221 ?   ?   ?   R . n 
A 1 247 GLY 247 222 ?   ?   ?   R . n 
A 1 248 ARG 248 223 ?   ?   ?   R . n 
A 1 249 GLU 249 224 224 GLU GLU R . n 
A 1 250 PHE 250 225 225 PHE PHE R . n 
A 1 251 LYS 251 226 226 LYS LYS R . n 
A 1 252 THR 252 227 227 THR THR R . n 
A 1 253 ALA 253 228 228 ALA ALA R . n 
A 1 254 LYS 254 229 229 LYS LYS R . n 
A 1 255 SER 255 230 230 SER SER R . n 
A 1 256 LEU 256 231 231 LEU LEU R . n 
A 1 257 LEU 257 232 232 LEU LEU R . n 
A 1 258 LEU 258 233 233 LEU LEU R . n 
A 1 259 VAL 259 234 234 VAL VAL R . n 
A 1 260 LEU 260 235 235 LEU LEU R . n 
A 1 261 PHE 261 236 236 PHE PHE R . n 
A 1 262 LEU 262 237 237 LEU LEU R . n 
A 1 263 PHE 263 238 238 PHE PHE R . n 
A 1 264 ALA 264 239 239 ALA ALA R . n 
A 1 265 LEU 265 240 240 LEU LEU R . n 
A 1 266 CYS 266 241 241 CYS CYS R . n 
A 1 267 TRP 267 242 242 TRP TRP R . n 
A 1 268 LEU 268 243 243 LEU LEU R . n 
A 1 269 PRO 269 244 244 PRO PRO R . n 
A 1 270 LEU 270 245 245 LEU LEU R . n 
A 1 271 SER 271 246 246 SER SER R . n 
A 1 272 ILE 272 247 247 ILE ILE R . n 
A 1 273 ILE 273 248 248 ILE ILE R . n 
A 1 274 ASN 274 249 249 ASN ASN R . n 
A 1 275 CYS 275 250 250 CYS CYS R . n 
A 1 276 ILE 276 251 251 ILE ILE R . n 
A 1 277 LEU 277 252 252 LEU LEU R . n 
A 1 278 TYR 278 253 253 TYR TYR R . n 
A 1 279 PHE 279 254 254 PHE PHE R . n 
A 1 280 ASP 280 255 255 ASP ASP R . n 
A 1 281 GLY 281 256 256 GLY GLY R . n 
A 1 282 GLN 282 257 257 GLN GLN R . n 
A 1 283 VAL 283 258 258 VAL VAL R . n 
A 1 284 PRO 284 259 259 PRO PRO R . n 
A 1 285 GLN 285 260 260 GLN GLN R . n 
A 1 286 THR 286 261 261 THR THR R . n 
A 1 287 VAL 287 262 262 VAL VAL R . n 
A 1 288 LEU 288 263 263 LEU LEU R . n 
A 1 289 TYR 289 264 264 TYR TYR R . n 
A 1 290 LEU 290 265 265 LEU LEU R . n 
A 1 291 GLY 291 266 266 GLY GLY R . n 
A 1 292 ILE 292 267 267 ILE ILE R . n 
A 1 293 LEU 293 268 268 LEU LEU R . n 
A 1 294 LEU 294 269 269 LEU LEU R . n 
A 1 295 SER 295 270 270 SER SER R . n 
A 1 296 HIS 296 271 271 HIS HIS R . n 
A 1 297 ALA 297 272 272 ALA ALA R . n 
A 1 298 ASN 298 273 273 ASN ASN R . n 
A 1 299 SER 299 274 274 SER SER R . n 
A 1 300 MET 300 275 275 MET MET R . n 
A 1 301 MET 301 276 276 MET MET R . n 
A 1 302 ASN 302 277 277 ASN ASN R . n 
A 1 303 PRO 303 278 278 PRO PRO R . n 
A 1 304 ILE 304 279 279 ILE ILE R . n 
A 1 305 VAL 305 280 280 VAL VAL R . n 
A 1 306 TYR 306 281 281 TYR TYR R . n 
A 1 307 ALA 307 282 282 ALA ALA R . n 
A 1 308 TYR 308 283 283 TYR TYR R . n 
A 1 309 LYS 309 284 284 LYS LYS R . n 
A 1 310 ILE 310 285 285 ILE ILE R . n 
A 1 311 LYS 311 286 286 LYS LYS R . n 
A 1 312 LYS 312 287 287 LYS LYS R . n 
A 1 313 PHE 313 288 288 PHE PHE R . n 
A 1 314 LYS 314 289 289 LYS LYS R . n 
A 1 315 GLU 315 290 290 GLU GLU R . n 
A 1 316 THR 316 291 291 THR THR R . n 
A 1 317 TYR 317 292 292 TYR TYR R . n 
A 1 318 LEU 318 293 293 LEU LEU R . n 
A 1 319 LEU 319 294 294 LEU LEU R . n 
A 1 320 ILE 320 295 295 ILE ILE R . n 
A 1 321 LEU 321 296 ?   ?   ?   R . n 
A 1 322 LYS 322 297 ?   ?   ?   R . n 
A 1 323 ALA 323 298 ?   ?   ?   R . n 
A 1 324 CYS 324 299 ?   ?   ?   R . n 
A 1 325 VAL 325 300 ?   ?   ?   R . n 
A 1 326 ILE 326 301 ?   ?   ?   R . n 
A 1 327 CYS 327 302 ?   ?   ?   R . n 
A 1 328 GLN 328 303 ?   ?   ?   R . n 
A 1 329 PRO 329 304 ?   ?   ?   R . n 
A 1 330 SER 330 305 ?   ?   ?   R . n 
A 1 331 LYS 331 306 ?   ?   ?   R . n 
A 1 332 SER 332 307 ?   ?   ?   R . n 
A 1 333 MET 333 308 ?   ?   ?   R . n 
A 1 334 ASP 334 309 ?   ?   ?   R . n 
A 1 335 PRO 335 310 ?   ?   ?   R . n 
A 1 336 SER 336 311 ?   ?   ?   R . n 
A 1 337 THR 337 312 ?   ?   ?   R . n 
A 1 338 GLU 338 313 ?   ?   ?   R . n 
A 1 339 GLN 339 314 ?   ?   ?   R . n 
A 1 340 THR 340 315 ?   ?   ?   R . n 
A 1 341 SER 341 316 ?   ?   ?   R . n 
A 1 342 GLU 342 317 ?   ?   ?   R . n 
A 1 343 GLY 343 318 ?   ?   ?   R . n 
A 1 344 SER 344 319 ?   ?   ?   R . n 
A 1 345 GLY 345 320 ?   ?   ?   R . n 
A 1 346 GLY 346 321 ?   ?   ?   R . n 
A 1 347 GLY 347 322 ?   ?   ?   R . n 
A 1 348 GLY 348 323 ?   ?   ?   R . n 
A 1 349 SER 349 324 ?   ?   ?   R . n 
A 1 350 GLY 350 325 ?   ?   ?   R . n 
A 1 351 GLY 351 326 ?   ?   ?   R . n 
A 1 352 SER 352 327 ?   ?   ?   R . n 
A 1 353 SER 353 328 ?   ?   ?   R . n 
A 1 354 SER 354 329 ?   ?   ?   R . n 
A 1 355 GLY 355 330 ?   ?   ?   R . n 
A 1 356 GLY 356 331 ?   ?   ?   R . n 
A 1 357 VAL 357 332 ?   ?   ?   R . n 
A 1 358 PHE 358 333 ?   ?   ?   R . n 
A 1 359 THR 359 334 ?   ?   ?   R . n 
A 1 360 LEU 360 335 ?   ?   ?   R . n 
A 1 361 GLU 361 336 ?   ?   ?   R . n 
A 1 362 ASP 362 337 ?   ?   ?   R . n 
A 1 363 PHE 363 338 ?   ?   ?   R . n 
A 1 364 VAL 364 339 ?   ?   ?   R . n 
A 1 365 GLY 365 340 ?   ?   ?   R . n 
A 1 366 ASP 366 341 ?   ?   ?   R . n 
A 1 367 TRP 367 342 ?   ?   ?   R . n 
A 1 368 GLU 368 343 ?   ?   ?   R . n 
A 1 369 GLN 369 344 ?   ?   ?   R . n 
A 1 370 THR 370 345 ?   ?   ?   R . n 
A 1 371 ALA 371 346 ?   ?   ?   R . n 
A 1 372 ALA 372 347 ?   ?   ?   R . n 
A 1 373 TYR 373 348 ?   ?   ?   R . n 
A 1 374 ASN 374 349 ?   ?   ?   R . n 
A 1 375 LEU 375 350 ?   ?   ?   R . n 
A 1 376 ASP 376 351 ?   ?   ?   R . n 
A 1 377 GLN 377 352 ?   ?   ?   R . n 
A 1 378 VAL 378 353 ?   ?   ?   R . n 
A 1 379 LEU 379 354 ?   ?   ?   R . n 
A 1 380 GLU 380 355 ?   ?   ?   R . n 
A 1 381 GLN 381 356 ?   ?   ?   R . n 
A 1 382 GLY 382 357 ?   ?   ?   R . n 
A 1 383 GLY 383 358 ?   ?   ?   R . n 
A 1 384 VAL 384 359 ?   ?   ?   R . n 
A 1 385 SER 385 360 ?   ?   ?   R . n 
A 1 386 SER 386 361 ?   ?   ?   R . n 
A 1 387 LEU 387 362 ?   ?   ?   R . n 
A 1 388 LEU 388 363 ?   ?   ?   R . n 
A 1 389 GLN 389 364 ?   ?   ?   R . n 
A 1 390 ASN 390 365 ?   ?   ?   R . n 
A 1 391 LEU 391 366 ?   ?   ?   R . n 
A 1 392 ALA 392 367 ?   ?   ?   R . n 
A 1 393 VAL 393 368 ?   ?   ?   R . n 
A 1 394 SER 394 369 ?   ?   ?   R . n 
A 1 395 VAL 395 370 ?   ?   ?   R . n 
A 1 396 THR 396 371 ?   ?   ?   R . n 
A 1 397 PRO 397 372 ?   ?   ?   R . n 
A 1 398 ILE 398 373 ?   ?   ?   R . n 
A 1 399 GLN 399 374 ?   ?   ?   R . n 
A 1 400 ARG 400 375 ?   ?   ?   R . n 
A 1 401 ILE 401 376 ?   ?   ?   R . n 
A 1 402 VAL 402 377 ?   ?   ?   R . n 
A 1 403 ARG 403 378 ?   ?   ?   R . n 
A 1 404 SER 404 379 ?   ?   ?   R . n 
A 1 405 GLY 405 380 ?   ?   ?   R . n 
A 1 406 GLU 406 381 ?   ?   ?   R . n 
A 1 407 ASN 407 382 ?   ?   ?   R . n 
A 1 408 ALA 408 383 ?   ?   ?   R . n 
A 1 409 LEU 409 384 ?   ?   ?   R . n 
A 1 410 LYS 410 385 ?   ?   ?   R . n 
A 1 411 ILE 411 386 ?   ?   ?   R . n 
A 1 412 ASP 412 387 ?   ?   ?   R . n 
A 1 413 ILE 413 388 ?   ?   ?   R . n 
A 1 414 HIS 414 389 ?   ?   ?   R . n 
A 1 415 VAL 415 390 ?   ?   ?   R . n 
A 1 416 ILE 416 391 ?   ?   ?   R . n 
A 1 417 ILE 417 392 ?   ?   ?   R . n 
A 1 418 PRO 418 393 ?   ?   ?   R . n 
A 1 419 TYR 419 394 ?   ?   ?   R . n 
A 1 420 GLU 420 395 ?   ?   ?   R . n 
A 1 421 GLY 421 396 ?   ?   ?   R . n 
A 1 422 LEU 422 397 ?   ?   ?   R . n 
A 1 423 SER 423 398 ?   ?   ?   R . n 
A 1 424 ALA 424 399 ?   ?   ?   R . n 
A 1 425 ASP 425 400 ?   ?   ?   R . n 
A 1 426 GLN 426 401 ?   ?   ?   R . n 
A 1 427 MET 427 402 ?   ?   ?   R . n 
A 1 428 ALA 428 403 ?   ?   ?   R . n 
A 1 429 GLN 429 404 ?   ?   ?   R . n 
A 1 430 ILE 430 405 ?   ?   ?   R . n 
A 1 431 GLU 431 406 ?   ?   ?   R . n 
A 1 432 GLU 432 407 ?   ?   ?   R . n 
A 1 433 VAL 433 408 ?   ?   ?   R . n 
A 1 434 PHE 434 409 ?   ?   ?   R . n 
A 1 435 LYS 435 410 ?   ?   ?   R . n 
A 1 436 VAL 436 411 ?   ?   ?   R . n 
A 1 437 VAL 437 412 ?   ?   ?   R . n 
A 1 438 TYR 438 413 ?   ?   ?   R . n 
A 1 439 PRO 439 414 ?   ?   ?   R . n 
A 1 440 VAL 440 415 ?   ?   ?   R . n 
A 1 441 ASP 441 416 ?   ?   ?   R . n 
A 1 442 ASP 442 417 ?   ?   ?   R . n 
A 1 443 HIS 443 418 ?   ?   ?   R . n 
A 1 444 HIS 444 419 ?   ?   ?   R . n 
A 1 445 PHE 445 420 ?   ?   ?   R . n 
A 1 446 LYS 446 421 ?   ?   ?   R . n 
A 1 447 VAL 447 422 ?   ?   ?   R . n 
A 1 448 ILE 448 423 ?   ?   ?   R . n 
A 1 449 LEU 449 424 ?   ?   ?   R . n 
A 1 450 PRO 450 425 ?   ?   ?   R . n 
A 1 451 TYR 451 426 ?   ?   ?   R . n 
A 1 452 GLY 452 427 ?   ?   ?   R . n 
A 1 453 THR 453 428 ?   ?   ?   R . n 
A 1 454 LEU 454 429 ?   ?   ?   R . n 
A 1 455 VAL 455 430 ?   ?   ?   R . n 
A 1 456 ILE 456 431 ?   ?   ?   R . n 
A 1 457 ASP 457 432 ?   ?   ?   R . n 
A 1 458 GLY 458 433 ?   ?   ?   R . n 
A 1 459 VAL 459 434 ?   ?   ?   R . n 
A 1 460 THR 460 435 ?   ?   ?   R . n 
A 1 461 PRO 461 436 ?   ?   ?   R . n 
A 1 462 ASN 462 437 ?   ?   ?   R . n 
A 1 463 MET 463 438 ?   ?   ?   R . n 
A 1 464 LEU 464 439 ?   ?   ?   R . n 
A 1 465 ASN 465 440 ?   ?   ?   R . n 
A 1 466 TYR 466 441 ?   ?   ?   R . n 
A 1 467 PHE 467 442 ?   ?   ?   R . n 
A 1 468 GLY 468 443 ?   ?   ?   R . n 
A 1 469 ARG 469 444 ?   ?   ?   R . n 
A 1 470 PRO 470 445 ?   ?   ?   R . n 
A 1 471 TYR 471 446 ?   ?   ?   R . n 
A 1 472 GLU 472 447 ?   ?   ?   R . n 
A 1 473 GLY 473 448 ?   ?   ?   R . n 
A 1 474 ILE 474 449 ?   ?   ?   R . n 
A 1 475 ALA 475 450 ?   ?   ?   R . n 
A 1 476 VAL 476 451 ?   ?   ?   R . n 
A 1 477 PHE 477 452 ?   ?   ?   R . n 
A 1 478 ASP 478 453 ?   ?   ?   R . n 
A 1 479 GLY 479 454 ?   ?   ?   R . n 
A 1 480 LYS 480 455 ?   ?   ?   R . n 
A 1 481 LYS 481 456 ?   ?   ?   R . n 
A 1 482 ILE 482 457 ?   ?   ?   R . n 
A 1 483 THR 483 458 ?   ?   ?   R . n 
A 1 484 VAL 484 459 ?   ?   ?   R . n 
A 1 485 THR 485 460 ?   ?   ?   R . n 
A 1 486 GLY 486 461 ?   ?   ?   R . n 
A 1 487 THR 487 462 ?   ?   ?   R . n 
A 1 488 LEU 488 463 ?   ?   ?   R . n 
A 1 489 TRP 489 464 ?   ?   ?   R . n 
A 1 490 ASN 490 465 ?   ?   ?   R . n 
A 1 491 GLY 491 466 ?   ?   ?   R . n 
A 1 492 ASN 492 467 ?   ?   ?   R . n 
A 1 493 LYS 493 468 ?   ?   ?   R . n 
A 1 494 ILE 494 469 ?   ?   ?   R . n 
A 1 495 ILE 495 470 ?   ?   ?   R . n 
A 1 496 ASP 496 471 ?   ?   ?   R . n 
A 1 497 GLU 497 472 ?   ?   ?   R . n 
A 1 498 ARG 498 473 ?   ?   ?   R . n 
A 1 499 LEU 499 474 ?   ?   ?   R . n 
A 1 500 ILE 500 475 ?   ?   ?   R . n 
A 1 501 THR 501 476 ?   ?   ?   R . n 
A 1 502 PRO 502 477 ?   ?   ?   R . n 
A 1 503 ASP 503 478 ?   ?   ?   R . n 
A 1 504 GLY 504 479 ?   ?   ?   R . n 
A 1 505 SER 505 480 ?   ?   ?   R . n 
A 1 506 MET 506 481 ?   ?   ?   R . n 
A 1 507 LEU 507 482 ?   ?   ?   R . n 
A 1 508 PHE 508 483 ?   ?   ?   R . n 
A 1 509 ARG 509 484 ?   ?   ?   R . n 
A 1 510 VAL 510 485 ?   ?   ?   R . n 
A 1 511 THR 511 486 ?   ?   ?   R . n 
A 1 512 ILE 512 487 ?   ?   ?   R . n 
A 1 513 ASN 513 488 ?   ?   ?   R . n 
A 1 514 SER 514 489 ?   ?   ?   R . n 
A 1 515 GLY 515 490 ?   ?   ?   R . n 
A 1 516 GLY 516 491 ?   ?   ?   R . n 
A 1 517 SER 517 492 ?   ?   ?   R . n 
A 1 518 GLY 518 493 ?   ?   ?   R . n 
A 1 519 GLY 519 494 ?   ?   ?   R . n 
A 1 520 GLY 520 495 ?   ?   ?   R . n 
A 1 521 GLY 521 496 ?   ?   ?   R . n 
A 1 522 SER 522 497 ?   ?   ?   R . n 
A 1 523 GLY 523 498 ?   ?   ?   R . n 
A 1 524 GLY 524 499 ?   ?   ?   R . n 
A 1 525 SER 525 500 ?   ?   ?   R . n 
A 1 526 SER 526 501 ?   ?   ?   R . n 
A 1 527 SER 527 502 ?   ?   ?   R . n 
A 1 528 GLY 528 503 ?   ?   ?   R . n 
A 1 529 GLY 529 504 ?   ?   ?   R . n 
A 1 530 LEU 530 505 ?   ?   ?   R . n 
A 1 531 GLU 531 506 ?   ?   ?   R . n 
A 1 532 VAL 532 507 ?   ?   ?   R . n 
A 1 533 LEU 533 508 ?   ?   ?   R . n 
A 1 534 PHE 534 509 ?   ?   ?   R . n 
A 1 535 GLN 535 510 ?   ?   ?   R . n 
A 1 536 GLY 536 511 ?   ?   ?   R . n 
A 1 537 PRO 537 512 ?   ?   ?   R . n 
A 1 538 GLY 538 513 ?   ?   ?   R . n 
A 1 539 SER 539 514 ?   ?   ?   R . n 
A 1 540 ALA 540 515 ?   ?   ?   R . n 
A 1 541 ALA 541 516 ?   ?   ?   R . n 
A 1 542 ALA 542 517 ?   ?   ?   R . n 
A 1 543 ALA 543 518 ?   ?   ?   R . n 
A 1 544 VAL 544 519 ?   ?   ?   R . n 
A 1 545 SER 545 520 ?   ?   ?   R . n 
A 1 546 LYS 546 521 ?   ?   ?   R . n 
A 1 547 GLY 547 522 ?   ?   ?   R . n 
A 1 548 GLU 548 523 ?   ?   ?   R . n 
A 1 549 GLU 549 524 ?   ?   ?   R . n 
A 1 550 LEU 550 525 ?   ?   ?   R . n 
A 1 551 PHE 551 526 ?   ?   ?   R . n 
A 1 552 THR 552 527 ?   ?   ?   R . n 
A 1 553 GLY 553 528 ?   ?   ?   R . n 
A 1 554 VAL 554 529 ?   ?   ?   R . n 
A 1 555 VAL 555 530 ?   ?   ?   R . n 
A 1 556 PRO 556 531 ?   ?   ?   R . n 
A 1 557 ILE 557 532 ?   ?   ?   R . n 
A 1 558 LEU 558 533 ?   ?   ?   R . n 
A 1 559 VAL 559 534 ?   ?   ?   R . n 
A 1 560 GLU 560 535 ?   ?   ?   R . n 
A 1 561 LEU 561 536 ?   ?   ?   R . n 
A 1 562 ASP 562 537 ?   ?   ?   R . n 
A 1 563 GLY 563 538 ?   ?   ?   R . n 
A 1 564 ASP 564 539 ?   ?   ?   R . n 
A 1 565 VAL 565 540 ?   ?   ?   R . n 
A 1 566 ASN 566 541 ?   ?   ?   R . n 
A 1 567 GLY 567 542 ?   ?   ?   R . n 
A 1 568 HIS 568 543 ?   ?   ?   R . n 
A 1 569 LYS 569 544 ?   ?   ?   R . n 
A 1 570 PHE 570 545 ?   ?   ?   R . n 
A 1 571 SER 571 546 ?   ?   ?   R . n 
A 1 572 VAL 572 547 ?   ?   ?   R . n 
A 1 573 SER 573 548 ?   ?   ?   R . n 
A 1 574 GLY 574 549 ?   ?   ?   R . n 
A 1 575 GLU 575 550 ?   ?   ?   R . n 
A 1 576 GLY 576 551 ?   ?   ?   R . n 
A 1 577 GLU 577 552 ?   ?   ?   R . n 
A 1 578 GLY 578 553 ?   ?   ?   R . n 
A 1 579 ASP 579 554 ?   ?   ?   R . n 
A 1 580 ALA 580 555 ?   ?   ?   R . n 
A 1 581 THR 581 556 ?   ?   ?   R . n 
A 1 582 TYR 582 557 ?   ?   ?   R . n 
A 1 583 GLY 583 558 ?   ?   ?   R . n 
A 1 584 LYS 584 559 ?   ?   ?   R . n 
A 1 585 LEU 585 560 ?   ?   ?   R . n 
A 1 586 THR 586 561 ?   ?   ?   R . n 
A 1 587 LEU 587 562 ?   ?   ?   R . n 
A 1 588 LYS 588 563 ?   ?   ?   R . n 
A 1 589 PHE 589 564 ?   ?   ?   R . n 
A 1 590 ILE 590 565 ?   ?   ?   R . n 
A 1 591 CYS 591 566 ?   ?   ?   R . n 
A 1 592 THR 592 567 ?   ?   ?   R . n 
A 1 593 THR 593 568 ?   ?   ?   R . n 
A 1 594 GLY 594 569 ?   ?   ?   R . n 
A 1 595 LYS 595 570 ?   ?   ?   R . n 
A 1 596 LEU 596 571 ?   ?   ?   R . n 
A 1 597 PRO 597 572 ?   ?   ?   R . n 
A 1 598 VAL 598 573 ?   ?   ?   R . n 
A 1 599 PRO 599 574 ?   ?   ?   R . n 
A 1 600 TRP 600 575 ?   ?   ?   R . n 
A 1 601 PRO 601 576 ?   ?   ?   R . n 
A 1 602 THR 602 577 ?   ?   ?   R . n 
A 1 603 LEU 603 578 ?   ?   ?   R . n 
A 1 604 VAL 604 579 ?   ?   ?   R . n 
A 1 605 THR 605 580 ?   ?   ?   R . n 
A 1 606 THR 606 581 ?   ?   ?   R . n 
A 1 607 LEU 607 582 ?   ?   ?   R . n 
A 1 608 THR 608 583 ?   ?   ?   R . n 
A 1 609 TYR 609 584 ?   ?   ?   R . n 
A 1 610 GLY 610 585 ?   ?   ?   R . n 
A 1 611 VAL 611 586 ?   ?   ?   R . n 
A 1 612 GLN 612 587 ?   ?   ?   R . n 
A 1 613 CYS 613 588 ?   ?   ?   R . n 
A 1 614 PHE 614 589 ?   ?   ?   R . n 
A 1 615 SER 615 590 ?   ?   ?   R . n 
A 1 616 ARG 616 591 ?   ?   ?   R . n 
A 1 617 TYR 617 592 ?   ?   ?   R . n 
A 1 618 PRO 618 593 ?   ?   ?   R . n 
A 1 619 ASP 619 594 ?   ?   ?   R . n 
A 1 620 HIS 620 595 ?   ?   ?   R . n 
A 1 621 MET 621 596 ?   ?   ?   R . n 
A 1 622 LYS 622 597 ?   ?   ?   R . n 
A 1 623 GLN 623 598 ?   ?   ?   R . n 
A 1 624 HIS 624 599 ?   ?   ?   R . n 
A 1 625 ASP 625 600 ?   ?   ?   R . n 
A 1 626 PHE 626 601 ?   ?   ?   R . n 
A 1 627 PHE 627 602 ?   ?   ?   R . n 
A 1 628 LYS 628 603 ?   ?   ?   R . n 
A 1 629 SER 629 604 ?   ?   ?   R . n 
A 1 630 ALA 630 605 ?   ?   ?   R . n 
A 1 631 MET 631 606 ?   ?   ?   R . n 
A 1 632 PRO 632 607 ?   ?   ?   R . n 
A 1 633 GLU 633 608 ?   ?   ?   R . n 
A 1 634 GLY 634 609 ?   ?   ?   R . n 
A 1 635 TYR 635 610 ?   ?   ?   R . n 
A 1 636 VAL 636 611 ?   ?   ?   R . n 
A 1 637 GLN 637 612 ?   ?   ?   R . n 
A 1 638 GLU 638 613 ?   ?   ?   R . n 
A 1 639 ARG 639 614 ?   ?   ?   R . n 
A 1 640 THR 640 615 ?   ?   ?   R . n 
A 1 641 ILE 641 616 ?   ?   ?   R . n 
A 1 642 PHE 642 617 ?   ?   ?   R . n 
A 1 643 PHE 643 618 ?   ?   ?   R . n 
A 1 644 LYS 644 619 ?   ?   ?   R . n 
A 1 645 ASP 645 620 ?   ?   ?   R . n 
A 1 646 ASP 646 621 ?   ?   ?   R . n 
A 1 647 GLY 647 622 ?   ?   ?   R . n 
A 1 648 ASN 648 623 ?   ?   ?   R . n 
A 1 649 TYR 649 624 ?   ?   ?   R . n 
A 1 650 LYS 650 625 ?   ?   ?   R . n 
A 1 651 THR 651 626 ?   ?   ?   R . n 
A 1 652 ARG 652 627 ?   ?   ?   R . n 
A 1 653 ALA 653 628 ?   ?   ?   R . n 
A 1 654 GLU 654 629 ?   ?   ?   R . n 
A 1 655 VAL 655 630 ?   ?   ?   R . n 
A 1 656 LYS 656 631 ?   ?   ?   R . n 
A 1 657 PHE 657 632 ?   ?   ?   R . n 
A 1 658 GLU 658 633 ?   ?   ?   R . n 
A 1 659 GLY 659 634 ?   ?   ?   R . n 
A 1 660 ASP 660 635 ?   ?   ?   R . n 
A 1 661 THR 661 636 ?   ?   ?   R . n 
A 1 662 LEU 662 637 ?   ?   ?   R . n 
A 1 663 VAL 663 638 ?   ?   ?   R . n 
A 1 664 ASN 664 639 ?   ?   ?   R . n 
A 1 665 ARG 665 640 ?   ?   ?   R . n 
A 1 666 ILE 666 641 ?   ?   ?   R . n 
A 1 667 GLU 667 642 ?   ?   ?   R . n 
A 1 668 LEU 668 643 ?   ?   ?   R . n 
A 1 669 LYS 669 644 ?   ?   ?   R . n 
A 1 670 GLY 670 645 ?   ?   ?   R . n 
A 1 671 ILE 671 646 ?   ?   ?   R . n 
A 1 672 ASP 672 647 ?   ?   ?   R . n 
A 1 673 PHE 673 648 ?   ?   ?   R . n 
A 1 674 LYS 674 649 ?   ?   ?   R . n 
A 1 675 GLU 675 650 ?   ?   ?   R . n 
A 1 676 ASP 676 651 ?   ?   ?   R . n 
A 1 677 GLY 677 652 ?   ?   ?   R . n 
A 1 678 ASN 678 653 ?   ?   ?   R . n 
A 1 679 ILE 679 654 ?   ?   ?   R . n 
A 1 680 LEU 680 655 ?   ?   ?   R . n 
A 1 681 GLY 681 656 ?   ?   ?   R . n 
A 1 682 HIS 682 657 ?   ?   ?   R . n 
A 1 683 LYS 683 658 ?   ?   ?   R . n 
A 1 684 LEU 684 659 ?   ?   ?   R . n 
A 1 685 GLU 685 660 ?   ?   ?   R . n 
A 1 686 TYR 686 661 ?   ?   ?   R . n 
A 1 687 ASN 687 662 ?   ?   ?   R . n 
A 1 688 TYR 688 663 ?   ?   ?   R . n 
A 1 689 ASN 689 664 ?   ?   ?   R . n 
A 1 690 SER 690 665 ?   ?   ?   R . n 
A 1 691 HIS 691 666 ?   ?   ?   R . n 
A 1 692 ASN 692 667 ?   ?   ?   R . n 
A 1 693 VAL 693 668 ?   ?   ?   R . n 
A 1 694 TYR 694 669 ?   ?   ?   R . n 
A 1 695 ILE 695 670 ?   ?   ?   R . n 
A 1 696 MET 696 671 ?   ?   ?   R . n 
A 1 697 ALA 697 672 ?   ?   ?   R . n 
A 1 698 ASP 698 673 ?   ?   ?   R . n 
A 1 699 LYS 699 674 ?   ?   ?   R . n 
A 1 700 GLN 700 675 ?   ?   ?   R . n 
A 1 701 LYS 701 676 ?   ?   ?   R . n 
A 1 702 ASN 702 677 ?   ?   ?   R . n 
A 1 703 GLY 703 678 ?   ?   ?   R . n 
A 1 704 ILE 704 679 ?   ?   ?   R . n 
A 1 705 LYS 705 680 ?   ?   ?   R . n 
A 1 706 VAL 706 681 ?   ?   ?   R . n 
A 1 707 ASN 707 682 ?   ?   ?   R . n 
A 1 708 PHE 708 683 ?   ?   ?   R . n 
A 1 709 LYS 709 684 ?   ?   ?   R . n 
A 1 710 ILE 710 685 ?   ?   ?   R . n 
A 1 711 ARG 711 686 ?   ?   ?   R . n 
A 1 712 HIS 712 687 ?   ?   ?   R . n 
A 1 713 ASN 713 688 ?   ?   ?   R . n 
A 1 714 ILE 714 689 ?   ?   ?   R . n 
A 1 715 GLU 715 690 ?   ?   ?   R . n 
A 1 716 ASP 716 691 ?   ?   ?   R . n 
A 1 717 GLY 717 692 ?   ?   ?   R . n 
A 1 718 SER 718 693 ?   ?   ?   R . n 
A 1 719 VAL 719 694 ?   ?   ?   R . n 
A 1 720 GLN 720 695 ?   ?   ?   R . n 
A 1 721 LEU 721 696 ?   ?   ?   R . n 
A 1 722 ALA 722 697 ?   ?   ?   R . n 
A 1 723 ASP 723 698 ?   ?   ?   R . n 
A 1 724 HIS 724 699 ?   ?   ?   R . n 
A 1 725 TYR 725 700 ?   ?   ?   R . n 
A 1 726 GLN 726 701 ?   ?   ?   R . n 
A 1 727 GLN 727 702 ?   ?   ?   R . n 
A 1 728 ASN 728 703 ?   ?   ?   R . n 
A 1 729 THR 729 704 ?   ?   ?   R . n 
A 1 730 PRO 730 705 ?   ?   ?   R . n 
A 1 731 ILE 731 706 ?   ?   ?   R . n 
A 1 732 GLY 732 707 ?   ?   ?   R . n 
A 1 733 ASP 733 708 ?   ?   ?   R . n 
A 1 734 GLY 734 709 ?   ?   ?   R . n 
A 1 735 PRO 735 710 ?   ?   ?   R . n 
A 1 736 VAL 736 711 ?   ?   ?   R . n 
A 1 737 LEU 737 712 ?   ?   ?   R . n 
A 1 738 LEU 738 713 ?   ?   ?   R . n 
A 1 739 PRO 739 714 ?   ?   ?   R . n 
A 1 740 ASP 740 715 ?   ?   ?   R . n 
A 1 741 ASN 741 716 ?   ?   ?   R . n 
A 1 742 HIS 742 717 ?   ?   ?   R . n 
A 1 743 TYR 743 718 ?   ?   ?   R . n 
A 1 744 LEU 744 719 ?   ?   ?   R . n 
A 1 745 SER 745 720 ?   ?   ?   R . n 
A 1 746 THR 746 721 ?   ?   ?   R . n 
A 1 747 GLN 747 722 ?   ?   ?   R . n 
A 1 748 SER 748 723 ?   ?   ?   R . n 
A 1 749 LYS 749 724 ?   ?   ?   R . n 
A 1 750 LEU 750 725 ?   ?   ?   R . n 
A 1 751 SER 751 726 ?   ?   ?   R . n 
A 1 752 LYS 752 727 ?   ?   ?   R . n 
A 1 753 ASP 753 728 ?   ?   ?   R . n 
A 1 754 PRO 754 729 ?   ?   ?   R . n 
A 1 755 ASN 755 730 ?   ?   ?   R . n 
A 1 756 GLU 756 731 ?   ?   ?   R . n 
A 1 757 LYS 757 732 ?   ?   ?   R . n 
A 1 758 ARG 758 733 ?   ?   ?   R . n 
A 1 759 ASP 759 734 ?   ?   ?   R . n 
A 1 760 HIS 760 735 ?   ?   ?   R . n 
A 1 761 MET 761 736 ?   ?   ?   R . n 
A 1 762 VAL 762 737 ?   ?   ?   R . n 
A 1 763 LEU 763 738 ?   ?   ?   R . n 
A 1 764 LEU 764 739 ?   ?   ?   R . n 
A 1 765 GLU 765 740 ?   ?   ?   R . n 
A 1 766 PHE 766 741 ?   ?   ?   R . n 
A 1 767 VAL 767 742 ?   ?   ?   R . n 
A 1 768 THR 768 743 ?   ?   ?   R . n 
A 1 769 ALA 769 744 ?   ?   ?   R . n 
A 1 770 ALA 770 745 ?   ?   ?   R . n 
A 1 771 GLY 771 746 ?   ?   ?   R . n 
A 1 772 ILE 772 747 ?   ?   ?   R . n 
A 1 773 THR 773 748 ?   ?   ?   R . n 
A 1 774 LEU 774 749 ?   ?   ?   R . n 
A 1 775 GLY 775 750 ?   ?   ?   R . n 
A 1 776 MET 776 751 ?   ?   ?   R . n 
A 1 777 ASP 777 752 ?   ?   ?   R . n 
A 1 778 GLU 778 753 ?   ?   ?   R . n 
A 1 779 LEU 779 754 ?   ?   ?   R . n 
A 1 780 TYR 780 755 ?   ?   ?   R . n 
A 1 781 LYS 781 756 ?   ?   ?   R . n 
A 1 782 SER 782 757 ?   ?   ?   R . n 
A 1 783 GLY 783 758 ?   ?   ?   R . n 
A 1 784 LEU 784 759 ?   ?   ?   R . n 
A 1 785 ARG 785 760 ?   ?   ?   R . n 
A 1 786 SER 786 761 ?   ?   ?   R . n 
A 1 787 HIS 787 762 ?   ?   ?   R . n 
A 1 788 HIS 788 763 ?   ?   ?   R . n 
A 1 789 HIS 789 764 ?   ?   ?   R . n 
A 1 790 HIS 790 765 ?   ?   ?   R . n 
A 1 791 HIS 791 766 ?   ?   ?   R . n 
A 1 792 HIS 792 767 ?   ?   ?   R . n 
A 1 793 HIS 793 768 ?   ?   ?   R . n 
A 1 794 HIS 794 769 ?   ?   ?   R . n 
B 2 1   MET 1   -78 ?   ?   ?   A . n 
B 2 2   ALA 2   -77 ?   ?   ?   A . n 
B 2 3   SER 3   -76 ?   ?   ?   A . n 
B 2 4   ASN 4   -75 ?   ?   ?   A . n 
B 2 5   ASN 5   -74 ?   ?   ?   A . n 
B 2 6   THR 6   -73 ?   ?   ?   A . n 
B 2 7   ALA 7   -72 ?   ?   ?   A . n 
B 2 8   SER 8   -71 ?   ?   ?   A . n 
B 2 9   ILE 9   -70 ?   ?   ?   A . n 
B 2 10  ALA 10  -69 ?   ?   ?   A . n 
B 2 11  GLN 11  -68 ?   ?   ?   A . n 
B 2 12  ALA 12  -67 ?   ?   ?   A . n 
B 2 13  ARG 13  -66 ?   ?   ?   A . n 
B 2 14  LYS 14  -65 ?   ?   ?   A . n 
B 2 15  LEU 15  -64 ?   ?   ?   A . n 
B 2 16  VAL 16  -63 ?   ?   ?   A . n 
B 2 17  GLU 17  -62 ?   ?   ?   A . n 
B 2 18  GLN 18  -61 ?   ?   ?   A . n 
B 2 19  LEU 19  -60 ?   ?   ?   A . n 
B 2 20  LYS 20  -59 ?   ?   ?   A . n 
B 2 21  MET 21  -58 ?   ?   ?   A . n 
B 2 22  GLU 22  -57 ?   ?   ?   A . n 
B 2 23  ALA 23  -56 ?   ?   ?   A . n 
B 2 24  ASN 24  -55 ?   ?   ?   A . n 
B 2 25  ILE 25  -54 ?   ?   ?   A . n 
B 2 26  ASP 26  -53 ?   ?   ?   A . n 
B 2 27  ARG 27  -52 ?   ?   ?   A . n 
B 2 28  ILE 28  -51 ?   ?   ?   A . n 
B 2 29  LYS 29  -50 ?   ?   ?   A . n 
B 2 30  VAL 30  -49 ?   ?   ?   A . n 
B 2 31  SER 31  -48 ?   ?   ?   A . n 
B 2 32  LYS 32  -47 ?   ?   ?   A . n 
B 2 33  ALA 33  -46 ?   ?   ?   A . n 
B 2 34  ALA 34  -45 ?   ?   ?   A . n 
B 2 35  ALA 35  -44 ?   ?   ?   A . n 
B 2 36  ASP 36  -43 ?   ?   ?   A . n 
B 2 37  LEU 37  -42 ?   ?   ?   A . n 
B 2 38  MET 38  -41 ?   ?   ?   A . n 
B 2 39  ALA 39  -40 ?   ?   ?   A . n 
B 2 40  TYR 40  -39 ?   ?   ?   A . n 
B 2 41  CYS 41  -38 ?   ?   ?   A . n 
B 2 42  GLU 42  -37 ?   ?   ?   A . n 
B 2 43  ALA 43  -36 ?   ?   ?   A . n 
B 2 44  HIS 44  -35 ?   ?   ?   A . n 
B 2 45  ALA 45  -34 ?   ?   ?   A . n 
B 2 46  LYS 46  -33 ?   ?   ?   A . n 
B 2 47  GLU 47  -32 ?   ?   ?   A . n 
B 2 48  ASP 48  -31 ?   ?   ?   A . n 
B 2 49  PRO 49  -30 ?   ?   ?   A . n 
B 2 50  LEU 50  -29 ?   ?   ?   A . n 
B 2 51  LEU 51  -28 ?   ?   ?   A . n 
B 2 52  THR 52  -27 ?   ?   ?   A . n 
B 2 53  PRO 53  -26 ?   ?   ?   A . n 
B 2 54  VAL 54  -25 ?   ?   ?   A . n 
B 2 55  PRO 55  -24 ?   ?   ?   A . n 
B 2 56  ALA 56  -23 ?   ?   ?   A . n 
B 2 57  SER 57  -22 ?   ?   ?   A . n 
B 2 58  GLU 58  -21 ?   ?   ?   A . n 
B 2 59  ASN 59  -20 ?   ?   ?   A . n 
B 2 60  PRO 60  -19 ?   ?   ?   A . n 
B 2 61  PHE 61  -18 ?   ?   ?   A . n 
B 2 62  ARG 62  -17 ?   ?   ?   A . n 
B 2 63  GLU 63  -16 ?   ?   ?   A . n 
B 2 64  LYS 64  -15 ?   ?   ?   A . n 
B 2 65  LYS 65  -14 ?   ?   ?   A . n 
B 2 66  PHE 66  -13 ?   ?   ?   A . n 
B 2 67  PHE 67  -12 ?   ?   ?   A . n 
B 2 68  CYS 68  -11 ?   ?   ?   A . n 
B 2 69  ALA 69  -10 ?   ?   ?   A . n 
B 2 70  ILE 70  -9  ?   ?   ?   A . n 
B 2 71  LEU 71  -8  ?   ?   ?   A . n 
B 2 72  GLY 72  -7  ?   ?   ?   A . n 
B 2 73  SER 73  -6  ?   ?   ?   A . n 
B 2 74  ALA 74  -5  ?   ?   ?   A . n 
B 2 75  GLY 75  -4  ?   ?   ?   A . n 
B 2 76  SER 76  -3  ?   ?   ?   A . n 
B 2 77  ALA 77  -2  ?   ?   ?   A . n 
B 2 78  GLY 78  -1  ?   ?   ?   A . n 
B 2 79  SER 79  0   ?   ?   ?   A . n 
B 2 80  ALA 80  1   ?   ?   ?   A . n 
B 2 81  MET 81  2   ?   ?   ?   A . n 
B 2 82  CYS 82  3   ?   ?   ?   A . n 
B 2 83  THR 83  4   4   THR THR A . n 
B 2 84  LEU 84  5   5   LEU LEU A . n 
B 2 85  SER 85  6   6   SER SER A . n 
B 2 86  ALA 86  7   7   ALA ALA A . n 
B 2 87  GLU 87  8   8   GLU GLU A . n 
B 2 88  ASP 88  9   9   ASP ASP A . n 
B 2 89  LYS 89  10  10  LYS LYS A . n 
B 2 90  ALA 90  11  11  ALA ALA A . n 
B 2 91  ALA 91  12  12  ALA ALA A . n 
B 2 92  VAL 92  13  13  VAL VAL A . n 
B 2 93  GLU 93  14  14  GLU GLU A . n 
B 2 94  ARG 94  15  15  ARG ARG A . n 
B 2 95  SER 95  16  16  SER SER A . n 
B 2 96  LYS 96  17  17  LYS LYS A . n 
B 2 97  MET 97  18  18  MET MET A . n 
B 2 98  ILE 98  19  19  ILE ILE A . n 
B 2 99  ASP 99  20  20  ASP ASP A . n 
B 2 100 ARG 100 21  21  ARG ARG A . n 
B 2 101 ASN 101 22  22  ASN ASN A . n 
B 2 102 LEU 102 23  23  LEU LEU A . n 
B 2 103 ARG 103 24  24  ARG ARG A . n 
B 2 104 GLU 104 25  25  GLU GLU A . n 
B 2 105 ASP 105 26  26  ASP ASP A . n 
B 2 106 GLY 106 27  27  GLY GLY A . n 
B 2 107 GLU 107 28  28  GLU GLU A . n 
B 2 108 LYS 108 29  29  LYS LYS A . n 
B 2 109 ALA 109 30  30  ALA ALA A . n 
B 2 110 ALA 110 31  31  ALA ALA A . n 
B 2 111 ARG 111 32  32  ARG ARG A . n 
B 2 112 GLU 112 33  33  GLU GLU A . n 
B 2 113 VAL 113 34  34  VAL VAL A . n 
B 2 114 LYS 114 35  35  LYS LYS A . n 
B 2 115 LEU 115 36  36  LEU LEU A . n 
B 2 116 LEU 116 37  37  LEU LEU A . n 
B 2 117 LEU 117 38  38  LEU LEU A . n 
B 2 118 LEU 118 39  39  LEU LEU A . n 
B 2 119 GLY 119 40  40  GLY GLY A . n 
B 2 120 ALA 120 41  41  ALA ALA A . n 
B 2 121 GLY 121 42  42  GLY GLY A . n 
B 2 122 GLU 122 43  43  GLU GLU A . n 
B 2 123 SER 123 44  44  SER SER A . n 
B 2 124 GLY 124 45  45  GLY GLY A . n 
B 2 125 LYS 125 46  46  LYS LYS A . n 
B 2 126 SER 126 47  47  SER SER A . n 
B 2 127 THR 127 48  48  THR THR A . n 
B 2 128 ILE 128 49  49  ILE ILE A . n 
B 2 129 VAL 129 50  50  VAL VAL A . n 
B 2 130 LYS 130 51  51  LYS LYS A . n 
B 2 131 GLN 131 52  52  GLN GLN A . n 
B 2 132 MET 132 53  53  MET MET A . n 
B 2 133 LYS 133 54  54  LYS LYS A . n 
B 2 134 ILE 134 55  ?   ?   ?   A . n 
B 2 135 ILE 135 56  ?   ?   ?   A . n 
B 2 136 HIS 136 57  ?   ?   ?   A . n 
B 2 137 GLU 137 58  ?   ?   ?   A . n 
B 2 138 ALA 138 59  ?   ?   ?   A . n 
B 2 139 GLY 139 60  ?   ?   ?   A . n 
B 2 140 TYR 140 61  ?   ?   ?   A . n 
B 2 141 SER 141 62  ?   ?   ?   A . n 
B 2 142 GLU 142 63  ?   ?   ?   A . n 
B 2 143 GLU 143 64  ?   ?   ?   A . n 
B 2 144 GLU 144 65  ?   ?   ?   A . n 
B 2 145 CYS 145 66  ?   ?   ?   A . n 
B 2 146 LYS 146 67  ?   ?   ?   A . n 
B 2 147 GLN 147 68  ?   ?   ?   A . n 
B 2 148 TYR 148 69  ?   ?   ?   A . n 
B 2 149 LYS 149 70  ?   ?   ?   A . n 
B 2 150 ALA 150 71  ?   ?   ?   A . n 
B 2 151 VAL 151 72  ?   ?   ?   A . n 
B 2 152 VAL 152 73  ?   ?   ?   A . n 
B 2 153 TYR 153 74  ?   ?   ?   A . n 
B 2 154 SER 154 75  ?   ?   ?   A . n 
B 2 155 ASN 155 76  ?   ?   ?   A . n 
B 2 156 THR 156 77  ?   ?   ?   A . n 
B 2 157 ILE 157 78  ?   ?   ?   A . n 
B 2 158 GLN 158 79  ?   ?   ?   A . n 
B 2 159 SER 159 80  ?   ?   ?   A . n 
B 2 160 ILE 160 81  ?   ?   ?   A . n 
B 2 161 ILE 161 82  ?   ?   ?   A . n 
B 2 162 ALA 162 83  ?   ?   ?   A . n 
B 2 163 ILE 163 84  ?   ?   ?   A . n 
B 2 164 ILE 164 85  ?   ?   ?   A . n 
B 2 165 ARG 165 86  ?   ?   ?   A . n 
B 2 166 ALA 166 87  ?   ?   ?   A . n 
B 2 167 MET 167 88  ?   ?   ?   A . n 
B 2 168 GLY 168 89  ?   ?   ?   A . n 
B 2 169 ARG 169 90  ?   ?   ?   A . n 
B 2 170 LEU 170 91  ?   ?   ?   A . n 
B 2 171 LYS 171 92  ?   ?   ?   A . n 
B 2 172 ILE 172 93  ?   ?   ?   A . n 
B 2 173 ASP 173 94  ?   ?   ?   A . n 
B 2 174 PHE 174 95  ?   ?   ?   A . n 
B 2 175 GLY 175 96  ?   ?   ?   A . n 
B 2 176 ASP 176 97  ?   ?   ?   A . n 
B 2 177 SER 177 98  ?   ?   ?   A . n 
B 2 178 ALA 178 99  ?   ?   ?   A . n 
B 2 179 ARG 179 100 ?   ?   ?   A . n 
B 2 180 ALA 180 101 ?   ?   ?   A . n 
B 2 181 ASP 181 102 ?   ?   ?   A . n 
B 2 182 ASP 182 103 ?   ?   ?   A . n 
B 2 183 ALA 183 104 ?   ?   ?   A . n 
B 2 184 ARG 184 105 ?   ?   ?   A . n 
B 2 185 GLN 185 106 ?   ?   ?   A . n 
B 2 186 LEU 186 107 ?   ?   ?   A . n 
B 2 187 PHE 187 108 ?   ?   ?   A . n 
B 2 188 VAL 188 109 ?   ?   ?   A . n 
B 2 189 LEU 189 110 ?   ?   ?   A . n 
B 2 190 ALA 190 111 ?   ?   ?   A . n 
B 2 191 GLY 191 112 ?   ?   ?   A . n 
B 2 192 ALA 192 113 ?   ?   ?   A . n 
B 2 193 ALA 193 114 ?   ?   ?   A . n 
B 2 194 GLU 194 115 ?   ?   ?   A . n 
B 2 195 GLU 195 116 ?   ?   ?   A . n 
B 2 196 GLY 196 117 ?   ?   ?   A . n 
B 2 197 PHE 197 118 ?   ?   ?   A . n 
B 2 198 MET 198 119 ?   ?   ?   A . n 
B 2 199 THR 199 120 ?   ?   ?   A . n 
B 2 200 ALA 200 121 ?   ?   ?   A . n 
B 2 201 GLU 201 122 ?   ?   ?   A . n 
B 2 202 LEU 202 123 ?   ?   ?   A . n 
B 2 203 ALA 203 124 ?   ?   ?   A . n 
B 2 204 GLY 204 125 ?   ?   ?   A . n 
B 2 205 VAL 205 126 ?   ?   ?   A . n 
B 2 206 ILE 206 127 ?   ?   ?   A . n 
B 2 207 LYS 207 128 ?   ?   ?   A . n 
B 2 208 ARG 208 129 ?   ?   ?   A . n 
B 2 209 LEU 209 130 ?   ?   ?   A . n 
B 2 210 TRP 210 131 ?   ?   ?   A . n 
B 2 211 LYS 211 132 ?   ?   ?   A . n 
B 2 212 ASP 212 133 ?   ?   ?   A . n 
B 2 213 SER 213 134 ?   ?   ?   A . n 
B 2 214 GLY 214 135 ?   ?   ?   A . n 
B 2 215 VAL 215 136 ?   ?   ?   A . n 
B 2 216 GLN 216 137 ?   ?   ?   A . n 
B 2 217 ALA 217 138 ?   ?   ?   A . n 
B 2 218 CYS 218 139 ?   ?   ?   A . n 
B 2 219 PHE 219 140 ?   ?   ?   A . n 
B 2 220 ASN 220 141 ?   ?   ?   A . n 
B 2 221 ARG 221 142 ?   ?   ?   A . n 
B 2 222 SER 222 143 ?   ?   ?   A . n 
B 2 223 ARG 223 144 ?   ?   ?   A . n 
B 2 224 GLU 224 145 ?   ?   ?   A . n 
B 2 225 TYR 225 146 ?   ?   ?   A . n 
B 2 226 GLN 226 147 ?   ?   ?   A . n 
B 2 227 LEU 227 148 ?   ?   ?   A . n 
B 2 228 ASN 228 149 ?   ?   ?   A . n 
B 2 229 ASP 229 150 ?   ?   ?   A . n 
B 2 230 SER 230 151 ?   ?   ?   A . n 
B 2 231 ALA 231 152 ?   ?   ?   A . n 
B 2 232 ALA 232 153 ?   ?   ?   A . n 
B 2 233 TYR 233 154 ?   ?   ?   A . n 
B 2 234 TYR 234 155 ?   ?   ?   A . n 
B 2 235 LEU 235 156 ?   ?   ?   A . n 
B 2 236 ASN 236 157 ?   ?   ?   A . n 
B 2 237 ASP 237 158 ?   ?   ?   A . n 
B 2 238 LEU 238 159 ?   ?   ?   A . n 
B 2 239 ASP 239 160 ?   ?   ?   A . n 
B 2 240 ARG 240 161 ?   ?   ?   A . n 
B 2 241 ILE 241 162 ?   ?   ?   A . n 
B 2 242 ALA 242 163 ?   ?   ?   A . n 
B 2 243 GLN 243 164 ?   ?   ?   A . n 
B 2 244 PRO 244 165 ?   ?   ?   A . n 
B 2 245 ASN 245 166 ?   ?   ?   A . n 
B 2 246 TYR 246 167 ?   ?   ?   A . n 
B 2 247 ILE 247 168 ?   ?   ?   A . n 
B 2 248 PRO 248 169 ?   ?   ?   A . n 
B 2 249 THR 249 170 ?   ?   ?   A . n 
B 2 250 GLN 250 171 ?   ?   ?   A . n 
B 2 251 GLN 251 172 ?   ?   ?   A . n 
B 2 252 ASP 252 173 ?   ?   ?   A . n 
B 2 253 VAL 253 174 ?   ?   ?   A . n 
B 2 254 LEU 254 175 ?   ?   ?   A . n 
B 2 255 ARG 255 176 ?   ?   ?   A . n 
B 2 256 THR 256 177 ?   ?   ?   A . n 
B 2 257 ARG 257 178 ?   ?   ?   A . n 
B 2 258 VAL 258 179 ?   ?   ?   A . n 
B 2 259 LYS 259 180 ?   ?   ?   A . n 
B 2 260 THR 260 181 ?   ?   ?   A . n 
B 2 261 THR 261 182 ?   ?   ?   A . n 
B 2 262 GLY 262 183 183 GLY GLY A . n 
B 2 263 ILE 263 184 184 ILE ILE A . n 
B 2 264 VAL 264 185 185 VAL VAL A . n 
B 2 265 GLU 265 186 186 GLU GLU A . n 
B 2 266 THR 266 187 187 THR THR A . n 
B 2 267 HIS 267 188 188 HIS HIS A . n 
B 2 268 PHE 268 189 189 PHE PHE A . n 
B 2 269 THR 269 190 190 THR THR A . n 
B 2 270 PHE 270 191 191 PHE PHE A . n 
B 2 271 LYS 271 192 192 LYS LYS A . n 
B 2 272 ASP 272 193 193 ASP ASP A . n 
B 2 273 LEU 273 194 194 LEU LEU A . n 
B 2 274 HIS 274 195 195 HIS HIS A . n 
B 2 275 PHE 275 196 196 PHE PHE A . n 
B 2 276 LYS 276 197 197 LYS LYS A . n 
B 2 277 MET 277 198 198 MET MET A . n 
B 2 278 PHE 278 199 199 PHE PHE A . n 
B 2 279 ASP 279 200 200 ASP ASP A . n 
B 2 280 VAL 280 201 201 VAL VAL A . n 
B 2 281 GLY 281 202 202 GLY GLY A . n 
B 2 282 GLY 282 203 203 GLY GLY A . n 
B 2 283 GLN 283 204 204 GLN GLN A . n 
B 2 284 ARG 284 205 205 ARG ARG A . n 
B 2 285 SER 285 206 206 SER SER A . n 
B 2 286 GLU 286 207 207 GLU GLU A . n 
B 2 287 ARG 287 208 208 ARG ARG A . n 
B 2 288 LYS 288 209 209 LYS LYS A . n 
B 2 289 LYS 289 210 210 LYS LYS A . n 
B 2 290 TRP 290 211 211 TRP TRP A . n 
B 2 291 ILE 291 212 212 ILE ILE A . n 
B 2 292 HIS 292 213 213 HIS HIS A . n 
B 2 293 CYS 293 214 214 CYS CYS A . n 
B 2 294 PHE 294 215 215 PHE PHE A . n 
B 2 295 GLU 295 216 216 GLU GLU A . n 
B 2 296 GLY 296 217 217 GLY GLY A . n 
B 2 297 VAL 297 218 218 VAL VAL A . n 
B 2 298 THR 298 219 219 THR THR A . n 
B 2 299 ALA 299 220 220 ALA ALA A . n 
B 2 300 ILE 300 221 221 ILE ILE A . n 
B 2 301 ILE 301 222 222 ILE ILE A . n 
B 2 302 PHE 302 223 223 PHE PHE A . n 
B 2 303 CYS 303 224 224 CYS CYS A . n 
B 2 304 VAL 304 225 225 VAL VAL A . n 
B 2 305 ALA 305 226 226 ALA ALA A . n 
B 2 306 LEU 306 227 227 LEU LEU A . n 
B 2 307 SER 307 228 228 SER SER A . n 
B 2 308 ASP 308 229 ?   ?   ?   A . n 
B 2 309 TYR 309 230 ?   ?   ?   A . n 
B 2 310 ASP 310 231 ?   ?   ?   A . n 
B 2 311 LEU 311 232 ?   ?   ?   A . n 
B 2 312 VAL 312 233 ?   ?   ?   A . n 
B 2 313 LEU 313 234 ?   ?   ?   A . n 
B 2 314 ALA 314 235 ?   ?   ?   A . n 
B 2 315 GLU 315 236 ?   ?   ?   A . n 
B 2 316 ASP 316 237 ?   ?   ?   A . n 
B 2 317 GLU 317 238 ?   ?   ?   A . n 
B 2 318 GLU 318 239 ?   ?   ?   A . n 
B 2 319 MET 319 240 ?   ?   ?   A . n 
B 2 320 ASN 320 241 241 ASN ASN A . n 
B 2 321 ARG 321 242 242 ARG ARG A . n 
B 2 322 MET 322 243 243 MET MET A . n 
B 2 323 HIS 323 244 244 HIS HIS A . n 
B 2 324 GLU 324 245 245 GLU GLU A . n 
B 2 325 SER 325 246 246 SER SER A . n 
B 2 326 MET 326 247 247 MET MET A . n 
B 2 327 LYS 327 248 248 LYS LYS A . n 
B 2 328 LEU 328 249 249 LEU LEU A . n 
B 2 329 PHE 329 250 250 PHE PHE A . n 
B 2 330 ASP 330 251 251 ASP ASP A . n 
B 2 331 SER 331 252 252 SER SER A . n 
B 2 332 ILE 332 253 253 ILE ILE A . n 
B 2 333 CYS 333 254 254 CYS CYS A . n 
B 2 334 ASN 334 255 255 ASN ASN A . n 
B 2 335 ASN 335 256 256 ASN ASN A . n 
B 2 336 LYS 336 257 257 LYS LYS A . n 
B 2 337 TRP 337 258 258 TRP TRP A . n 
B 2 338 PHE 338 259 259 PHE PHE A . n 
B 2 339 THR 339 260 260 THR THR A . n 
B 2 340 ASP 340 261 261 ASP ASP A . n 
B 2 341 THR 341 262 262 THR THR A . n 
B 2 342 SER 342 263 263 SER SER A . n 
B 2 343 ILE 343 264 264 ILE ILE A . n 
B 2 344 ILE 344 265 265 ILE ILE A . n 
B 2 345 LEU 345 266 266 LEU LEU A . n 
B 2 346 PHE 346 267 267 PHE PHE A . n 
B 2 347 LEU 347 268 268 LEU LEU A . n 
B 2 348 ASN 348 269 269 ASN ASN A . n 
B 2 349 LYS 349 270 270 LYS LYS A . n 
B 2 350 LYS 350 271 271 LYS LYS A . n 
B 2 351 ASP 351 272 272 ASP ASP A . n 
B 2 352 LEU 352 273 273 LEU LEU A . n 
B 2 353 PHE 353 274 274 PHE PHE A . n 
B 2 354 GLU 354 275 275 GLU GLU A . n 
B 2 355 GLU 355 276 276 GLU GLU A . n 
B 2 356 LYS 356 277 277 LYS LYS A . n 
B 2 357 ILE 357 278 278 ILE ILE A . n 
B 2 358 LYS 358 279 279 LYS LYS A . n 
B 2 359 LYS 359 280 280 LYS LYS A . n 
B 2 360 SER 360 281 281 SER SER A . n 
B 2 361 PRO 361 282 282 PRO PRO A . n 
B 2 362 LEU 362 283 283 LEU LEU A . n 
B 2 363 THR 363 284 284 THR THR A . n 
B 2 364 ILE 364 285 285 ILE ILE A . n 
B 2 365 CYS 365 286 286 CYS CYS A . n 
B 2 366 TYR 366 287 287 TYR TYR A . n 
B 2 367 PRO 367 288 288 PRO PRO A . n 
B 2 368 GLU 368 289 289 GLU GLU A . n 
B 2 369 TYR 369 290 290 TYR TYR A . n 
B 2 370 ALA 370 291 291 ALA ALA A . n 
B 2 371 GLY 371 292 292 GLY GLY A . n 
B 2 372 SER 372 293 293 SER SER A . n 
B 2 373 ASN 373 294 294 ASN ASN A . n 
B 2 374 THR 374 295 295 THR THR A . n 
B 2 375 TYR 375 296 296 TYR TYR A . n 
B 2 376 GLU 376 297 297 GLU GLU A . n 
B 2 377 GLU 377 298 298 GLU GLU A . n 
B 2 378 ALA 378 299 299 ALA ALA A . n 
B 2 379 ALA 379 300 300 ALA ALA A . n 
B 2 380 ALA 380 301 301 ALA ALA A . n 
B 2 381 TYR 381 302 302 TYR TYR A . n 
B 2 382 ILE 382 303 303 ILE ILE A . n 
B 2 383 GLN 383 304 304 GLN GLN A . n 
B 2 384 CYS 384 305 305 CYS CYS A . n 
B 2 385 GLN 385 306 306 GLN GLN A . n 
B 2 386 PHE 386 307 307 PHE PHE A . n 
B 2 387 GLU 387 308 308 GLU GLU A . n 
B 2 388 ASP 388 309 309 ASP ASP A . n 
B 2 389 LEU 389 310 310 LEU LEU A . n 
B 2 390 ASN 390 311 311 ASN ASN A . n 
B 2 391 LYS 391 312 312 LYS LYS A . n 
B 2 392 ARG 392 313 313 ARG ARG A . n 
B 2 393 LYS 393 314 314 LYS LYS A . n 
B 2 394 ASP 394 315 315 ASP ASP A . n 
B 2 395 THR 395 316 316 THR THR A . n 
B 2 396 LYS 396 317 317 LYS LYS A . n 
B 2 397 GLU 397 318 318 GLU GLU A . n 
B 2 398 ILE 398 319 319 ILE ILE A . n 
B 2 399 TYR 399 320 320 TYR TYR A . n 
B 2 400 THR 400 321 321 THR THR A . n 
B 2 401 HIS 401 322 322 HIS HIS A . n 
B 2 402 PHE 402 323 323 PHE PHE A . n 
B 2 403 THR 403 324 324 THR THR A . n 
B 2 404 CYS 404 325 325 CYS CYS A . n 
B 2 405 ALA 405 326 326 ALA ALA A . n 
B 2 406 THR 406 327 327 THR THR A . n 
B 2 407 ASP 407 328 328 ASP ASP A . n 
B 2 408 THR 408 329 329 THR THR A . n 
B 2 409 LYS 409 330 330 LYS LYS A . n 
B 2 410 ASN 410 331 331 ASN ASN A . n 
B 2 411 VAL 411 332 332 VAL VAL A . n 
B 2 412 GLN 412 333 333 GLN GLN A . n 
B 2 413 PHE 413 334 334 PHE PHE A . n 
B 2 414 VAL 414 335 335 VAL VAL A . n 
B 2 415 PHE 415 336 336 PHE PHE A . n 
B 2 416 ASP 416 337 337 ASP ASP A . n 
B 2 417 ALA 417 338 338 ALA ALA A . n 
B 2 418 VAL 418 339 339 VAL VAL A . n 
B 2 419 THR 419 340 340 THR THR A . n 
B 2 420 ASP 420 341 341 ASP ASP A . n 
B 2 421 VAL 421 342 342 VAL VAL A . n 
B 2 422 ILE 422 343 343 ILE ILE A . n 
B 2 423 ILE 423 344 344 ILE ILE A . n 
B 2 424 LYS 424 345 345 LYS LYS A . n 
B 2 425 ASN 425 346 346 ASN ASN A . n 
B 2 426 ASN 426 347 347 ASN ASN A . n 
B 2 427 LEU 427 348 348 LEU LEU A . n 
B 2 428 LYS 428 349 349 LYS LYS A . n 
B 2 429 ASP 429 350 350 ASP ASP A . n 
B 2 430 CYS 430 351 351 CYS CYS A . n 
B 2 431 GLY 431 352 352 GLY GLY A . n 
B 2 432 LEU 432 353 353 LEU LEU A . n 
B 2 433 PHE 433 354 354 PHE PHE A . n 
C 3 1   MET 1   -4  ?   ?   ?   B . n 
C 3 2   GLY 2   -3  ?   ?   ?   B . n 
C 3 3   SER 3   -2  ?   ?   ?   B . n 
C 3 4   LEU 4   -1  ?   ?   ?   B . n 
C 3 5   LEU 5   0   ?   ?   ?   B . n 
C 3 6   GLN 6   1   ?   ?   ?   B . n 
C 3 7   SER 7   2   ?   ?   ?   B . n 
C 3 8   GLU 8   3   ?   ?   ?   B . n 
C 3 9   LEU 9   4   ?   ?   ?   B . n 
C 3 10  ASP 10  5   5   ASP ASP B . n 
C 3 11  GLN 11  6   6   GLN GLN B . n 
C 3 12  LEU 12  7   7   LEU LEU B . n 
C 3 13  ARG 13  8   8   ARG ARG B . n 
C 3 14  GLN 14  9   9   GLN GLN B . n 
C 3 15  GLU 15  10  10  GLU GLU B . n 
C 3 16  ALA 16  11  11  ALA ALA B . n 
C 3 17  GLU 17  12  12  GLU GLU B . n 
C 3 18  GLN 18  13  13  GLN GLN B . n 
C 3 19  LEU 19  14  14  LEU LEU B . n 
C 3 20  LYS 20  15  15  LYS LYS B . n 
C 3 21  ASN 21  16  16  ASN ASN B . n 
C 3 22  GLN 22  17  17  GLN GLN B . n 
C 3 23  ILE 23  18  18  ILE ILE B . n 
C 3 24  ARG 24  19  19  ARG ARG B . n 
C 3 25  ASP 25  20  20  ASP ASP B . n 
C 3 26  ALA 26  21  21  ALA ALA B . n 
C 3 27  ARG 27  22  22  ARG ARG B . n 
C 3 28  LYS 28  23  23  LYS LYS B . n 
C 3 29  ALA 29  24  24  ALA ALA B . n 
C 3 30  CYS 30  25  25  CYS CYS B . n 
C 3 31  ALA 31  26  26  ALA ALA B . n 
C 3 32  ASP 32  27  27  ASP ASP B . n 
C 3 33  ALA 33  28  28  ALA ALA B . n 
C 3 34  THR 34  29  29  THR THR B . n 
C 3 35  LEU 35  30  30  LEU LEU B . n 
C 3 36  SER 36  31  31  SER SER B . n 
C 3 37  GLN 37  32  32  GLN GLN B . n 
C 3 38  ILE 38  33  33  ILE ILE B . n 
C 3 39  THR 39  34  34  THR THR B . n 
C 3 40  ASN 40  35  35  ASN ASN B . n 
C 3 41  ASN 41  36  36  ASN ASN B . n 
C 3 42  ILE 42  37  37  ILE ILE B . n 
C 3 43  ASP 43  38  38  ASP ASP B . n 
C 3 44  PRO 44  39  39  PRO PRO B . n 
C 3 45  VAL 45  40  40  VAL VAL B . n 
C 3 46  GLY 46  41  41  GLY GLY B . n 
C 3 47  ARG 47  42  42  ARG ARG B . n 
C 3 48  ILE 48  43  43  ILE ILE B . n 
C 3 49  GLN 49  44  44  GLN GLN B . n 
C 3 50  MET 50  45  45  MET MET B . n 
C 3 51  ARG 51  46  46  ARG ARG B . n 
C 3 52  THR 52  47  47  THR THR B . n 
C 3 53  ARG 53  48  48  ARG ARG B . n 
C 3 54  ARG 54  49  49  ARG ARG B . n 
C 3 55  THR 55  50  50  THR THR B . n 
C 3 56  LEU 56  51  51  LEU LEU B . n 
C 3 57  ARG 57  52  52  ARG ARG B . n 
C 3 58  GLY 58  53  53  GLY GLY B . n 
C 3 59  HIS 59  54  54  HIS HIS B . n 
C 3 60  LEU 60  55  55  LEU LEU B . n 
C 3 61  ALA 61  56  56  ALA ALA B . n 
C 3 62  LYS 62  57  57  LYS LYS B . n 
C 3 63  ILE 63  58  58  ILE ILE B . n 
C 3 64  TYR 64  59  59  TYR TYR B . n 
C 3 65  ALA 65  60  60  ALA ALA B . n 
C 3 66  MET 66  61  61  MET MET B . n 
C 3 67  HIS 67  62  62  HIS HIS B . n 
C 3 68  TRP 68  63  63  TRP TRP B . n 
C 3 69  GLY 69  64  64  GLY GLY B . n 
C 3 70  THR 70  65  65  THR THR B . n 
C 3 71  ASP 71  66  66  ASP ASP B . n 
C 3 72  SER 72  67  67  SER SER B . n 
C 3 73  ARG 73  68  68  ARG ARG B . n 
C 3 74  LEU 74  69  69  LEU LEU B . n 
C 3 75  LEU 75  70  70  LEU LEU B . n 
C 3 76  VAL 76  71  71  VAL VAL B . n 
C 3 77  SER 77  72  72  SER SER B . n 
C 3 78  ALA 78  73  73  ALA ALA B . n 
C 3 79  SER 79  74  74  SER SER B . n 
C 3 80  GLN 80  75  75  GLN GLN B . n 
C 3 81  ASP 81  76  76  ASP ASP B . n 
C 3 82  GLY 82  77  77  GLY GLY B . n 
C 3 83  LYS 83  78  78  LYS LYS B . n 
C 3 84  LEU 84  79  79  LEU LEU B . n 
C 3 85  ILE 85  80  80  ILE ILE B . n 
C 3 86  ILE 86  81  81  ILE ILE B . n 
C 3 87  TRP 87  82  82  TRP TRP B . n 
C 3 88  ASP 88  83  83  ASP ASP B . n 
C 3 89  SER 89  84  84  SER SER B . n 
C 3 90  TYR 90  85  85  TYR TYR B . n 
C 3 91  THR 91  86  86  THR THR B . n 
C 3 92  THR 92  87  87  THR THR B . n 
C 3 93  ASN 93  88  88  ASN ASN B . n 
C 3 94  LYS 94  89  89  LYS LYS B . n 
C 3 95  VAL 95  90  90  VAL VAL B . n 
C 3 96  HIS 96  91  91  HIS HIS B . n 
C 3 97  ALA 97  92  92  ALA ALA B . n 
C 3 98  ILE 98  93  93  ILE ILE B . n 
C 3 99  PRO 99  94  94  PRO PRO B . n 
C 3 100 LEU 100 95  95  LEU LEU B . n 
C 3 101 ARG 101 96  96  ARG ARG B . n 
C 3 102 SER 102 97  97  SER SER B . n 
C 3 103 SER 103 98  98  SER SER B . n 
C 3 104 TRP 104 99  99  TRP TRP B . n 
C 3 105 VAL 105 100 100 VAL VAL B . n 
C 3 106 MET 106 101 101 MET MET B . n 
C 3 107 THR 107 102 102 THR THR B . n 
C 3 108 CYS 108 103 103 CYS CYS B . n 
C 3 109 ALA 109 104 104 ALA ALA B . n 
C 3 110 TYR 110 105 105 TYR TYR B . n 
C 3 111 ALA 111 106 106 ALA ALA B . n 
C 3 112 PRO 112 107 107 PRO PRO B . n 
C 3 113 SER 113 108 108 SER SER B . n 
C 3 114 GLY 114 109 109 GLY GLY B . n 
C 3 115 ASN 115 110 110 ASN ASN B . n 
C 3 116 TYR 116 111 111 TYR TYR B . n 
C 3 117 VAL 117 112 112 VAL VAL B . n 
C 3 118 ALA 118 113 113 ALA ALA B . n 
C 3 119 CYS 119 114 114 CYS CYS B . n 
C 3 120 GLY 120 115 115 GLY GLY B . n 
C 3 121 GLY 121 116 116 GLY GLY B . n 
C 3 122 LEU 122 117 117 LEU LEU B . n 
C 3 123 ASP 123 118 118 ASP ASP B . n 
C 3 124 ASN 124 119 119 ASN ASN B . n 
C 3 125 ILE 125 120 120 ILE ILE B . n 
C 3 126 CYS 126 121 121 CYS CYS B . n 
C 3 127 SER 127 122 122 SER SER B . n 
C 3 128 ILE 128 123 123 ILE ILE B . n 
C 3 129 TYR 129 124 124 TYR TYR B . n 
C 3 130 ASN 130 125 125 ASN ASN B . n 
C 3 131 LEU 131 126 126 LEU LEU B . n 
C 3 132 LYS 132 127 127 LYS LYS B . n 
C 3 133 THR 133 128 128 THR THR B . n 
C 3 134 ARG 134 129 129 ARG ARG B . n 
C 3 135 GLU 135 130 130 GLU GLU B . n 
C 3 136 GLY 136 131 131 GLY GLY B . n 
C 3 137 ASN 137 132 132 ASN ASN B . n 
C 3 138 VAL 138 133 133 VAL VAL B . n 
C 3 139 ARG 139 134 134 ARG ARG B . n 
C 3 140 VAL 140 135 135 VAL VAL B . n 
C 3 141 SER 141 136 136 SER SER B . n 
C 3 142 ARG 142 137 137 ARG ARG B . n 
C 3 143 GLU 143 138 138 GLU GLU B . n 
C 3 144 LEU 144 139 139 LEU LEU B . n 
C 3 145 ALA 145 140 140 ALA ALA B . n 
C 3 146 GLY 146 141 141 GLY GLY B . n 
C 3 147 HIS 147 142 142 HIS HIS B . n 
C 3 148 THR 148 143 143 THR THR B . n 
C 3 149 GLY 149 144 144 GLY GLY B . n 
C 3 150 TYR 150 145 145 TYR TYR B . n 
C 3 151 LEU 151 146 146 LEU LEU B . n 
C 3 152 SER 152 147 147 SER SER B . n 
C 3 153 CYS 153 148 148 CYS CYS B . n 
C 3 154 CYS 154 149 149 CYS CYS B . n 
C 3 155 ARG 155 150 150 ARG ARG B . n 
C 3 156 PHE 156 151 151 PHE PHE B . n 
C 3 157 LEU 157 152 152 LEU LEU B . n 
C 3 158 ASP 158 153 153 ASP ASP B . n 
C 3 159 ASP 159 154 154 ASP ASP B . n 
C 3 160 ASN 160 155 155 ASN ASN B . n 
C 3 161 GLN 161 156 156 GLN GLN B . n 
C 3 162 ILE 162 157 157 ILE ILE B . n 
C 3 163 VAL 163 158 158 VAL VAL B . n 
C 3 164 THR 164 159 159 THR THR B . n 
C 3 165 SER 165 160 160 SER SER B . n 
C 3 166 SER 166 161 161 SER SER B . n 
C 3 167 GLY 167 162 162 GLY GLY B . n 
C 3 168 ASP 168 163 163 ASP ASP B . n 
C 3 169 THR 169 164 164 THR THR B . n 
C 3 170 THR 170 165 165 THR THR B . n 
C 3 171 CYS 171 166 166 CYS CYS B . n 
C 3 172 ALA 172 167 167 ALA ALA B . n 
C 3 173 LEU 173 168 168 LEU LEU B . n 
C 3 174 TRP 174 169 169 TRP TRP B . n 
C 3 175 ASP 175 170 170 ASP ASP B . n 
C 3 176 ILE 176 171 171 ILE ILE B . n 
C 3 177 GLU 177 172 172 GLU GLU B . n 
C 3 178 THR 178 173 173 THR THR B . n 
C 3 179 GLY 179 174 174 GLY GLY B . n 
C 3 180 GLN 180 175 175 GLN GLN B . n 
C 3 181 GLN 181 176 176 GLN GLN B . n 
C 3 182 THR 182 177 177 THR THR B . n 
C 3 183 THR 183 178 178 THR THR B . n 
C 3 184 THR 184 179 179 THR THR B . n 
C 3 185 PHE 185 180 180 PHE PHE B . n 
C 3 186 THR 186 181 181 THR THR B . n 
C 3 187 GLY 187 182 182 GLY GLY B . n 
C 3 188 HIS 188 183 183 HIS HIS B . n 
C 3 189 THR 189 184 184 THR THR B . n 
C 3 190 GLY 190 185 185 GLY GLY B . n 
C 3 191 ASP 191 186 186 ASP ASP B . n 
C 3 192 VAL 192 187 187 VAL VAL B . n 
C 3 193 MET 193 188 188 MET MET B . n 
C 3 194 SER 194 189 189 SER SER B . n 
C 3 195 LEU 195 190 190 LEU LEU B . n 
C 3 196 SER 196 191 191 SER SER B . n 
C 3 197 LEU 197 192 192 LEU LEU B . n 
C 3 198 ALA 198 193 193 ALA ALA B . n 
C 3 199 PRO 199 194 194 PRO PRO B . n 
C 3 200 ASP 200 195 195 ASP ASP B . n 
C 3 201 THR 201 196 196 THR THR B . n 
C 3 202 ARG 202 197 197 ARG ARG B . n 
C 3 203 LEU 203 198 198 LEU LEU B . n 
C 3 204 PHE 204 199 199 PHE PHE B . n 
C 3 205 VAL 205 200 200 VAL VAL B . n 
C 3 206 SER 206 201 201 SER SER B . n 
C 3 207 GLY 207 202 202 GLY GLY B . n 
C 3 208 ALA 208 203 203 ALA ALA B . n 
C 3 209 CYS 209 204 204 CYS CYS B . n 
C 3 210 ASP 210 205 205 ASP ASP B . n 
C 3 211 ALA 211 206 206 ALA ALA B . n 
C 3 212 SER 212 207 207 SER SER B . n 
C 3 213 ALA 213 208 208 ALA ALA B . n 
C 3 214 LYS 214 209 209 LYS LYS B . n 
C 3 215 LEU 215 210 210 LEU LEU B . n 
C 3 216 TRP 216 211 211 TRP TRP B . n 
C 3 217 ASP 217 212 212 ASP ASP B . n 
C 3 218 VAL 218 213 213 VAL VAL B . n 
C 3 219 ARG 219 214 214 ARG ARG B . n 
C 3 220 GLU 220 215 215 GLU GLU B . n 
C 3 221 GLY 221 216 216 GLY GLY B . n 
C 3 222 MET 222 217 217 MET MET B . n 
C 3 223 CYS 223 218 218 CYS CYS B . n 
C 3 224 ARG 224 219 219 ARG ARG B . n 
C 3 225 GLN 225 220 220 GLN GLN B . n 
C 3 226 THR 226 221 221 THR THR B . n 
C 3 227 PHE 227 222 222 PHE PHE B . n 
C 3 228 THR 228 223 223 THR THR B . n 
C 3 229 GLY 229 224 224 GLY GLY B . n 
C 3 230 HIS 230 225 225 HIS HIS B . n 
C 3 231 GLU 231 226 226 GLU GLU B . n 
C 3 232 SER 232 227 227 SER SER B . n 
C 3 233 ASP 233 228 228 ASP ASP B . n 
C 3 234 ILE 234 229 229 ILE ILE B . n 
C 3 235 ASN 235 230 230 ASN ASN B . n 
C 3 236 ALA 236 231 231 ALA ALA B . n 
C 3 237 ILE 237 232 232 ILE ILE B . n 
C 3 238 CYS 238 233 233 CYS CYS B . n 
C 3 239 PHE 239 234 234 PHE PHE B . n 
C 3 240 PHE 240 235 235 PHE PHE B . n 
C 3 241 PRO 241 236 236 PRO PRO B . n 
C 3 242 ASN 242 237 237 ASN ASN B . n 
C 3 243 GLY 243 238 238 GLY GLY B . n 
C 3 244 ASN 244 239 239 ASN ASN B . n 
C 3 245 ALA 245 240 240 ALA ALA B . n 
C 3 246 PHE 246 241 241 PHE PHE B . n 
C 3 247 ALA 247 242 242 ALA ALA B . n 
C 3 248 THR 248 243 243 THR THR B . n 
C 3 249 GLY 249 244 244 GLY GLY B . n 
C 3 250 SER 250 245 245 SER SER B . n 
C 3 251 ASP 251 246 246 ASP ASP B . n 
C 3 252 ASP 252 247 247 ASP ASP B . n 
C 3 253 ALA 253 248 248 ALA ALA B . n 
C 3 254 THR 254 249 249 THR THR B . n 
C 3 255 CYS 255 250 250 CYS CYS B . n 
C 3 256 ARG 256 251 251 ARG ARG B . n 
C 3 257 LEU 257 252 252 LEU LEU B . n 
C 3 258 PHE 258 253 253 PHE PHE B . n 
C 3 259 ASP 259 254 254 ASP ASP B . n 
C 3 260 LEU 260 255 255 LEU LEU B . n 
C 3 261 ARG 261 256 256 ARG ARG B . n 
C 3 262 ALA 262 257 257 ALA ALA B . n 
C 3 263 ASP 263 258 258 ASP ASP B . n 
C 3 264 GLN 264 259 259 GLN GLN B . n 
C 3 265 GLU 265 260 260 GLU GLU B . n 
C 3 266 LEU 266 261 261 LEU LEU B . n 
C 3 267 MET 267 262 262 MET MET B . n 
C 3 268 THR 268 263 263 THR THR B . n 
C 3 269 TYR 269 264 264 TYR TYR B . n 
C 3 270 SER 270 265 265 SER SER B . n 
C 3 271 HIS 271 266 266 HIS HIS B . n 
C 3 272 ASP 272 267 267 ASP ASP B . n 
C 3 273 ASN 273 268 268 ASN ASN B . n 
C 3 274 ILE 274 269 269 ILE ILE B . n 
C 3 275 ILE 275 270 270 ILE ILE B . n 
C 3 276 CYS 276 271 271 CYS CYS B . n 
C 3 277 GLY 277 272 272 GLY GLY B . n 
C 3 278 ILE 278 273 273 ILE ILE B . n 
C 3 279 THR 279 274 274 THR THR B . n 
C 3 280 SER 280 275 275 SER SER B . n 
C 3 281 VAL 281 276 276 VAL VAL B . n 
C 3 282 SER 282 277 277 SER SER B . n 
C 3 283 PHE 283 278 278 PHE PHE B . n 
C 3 284 SER 284 279 279 SER SER B . n 
C 3 285 LYS 285 280 280 LYS LYS B . n 
C 3 286 SER 286 281 281 SER SER B . n 
C 3 287 GLY 287 282 282 GLY GLY B . n 
C 3 288 ARG 288 283 283 ARG ARG B . n 
C 3 289 LEU 289 284 284 LEU LEU B . n 
C 3 290 LEU 290 285 285 LEU LEU B . n 
C 3 291 LEU 291 286 286 LEU LEU B . n 
C 3 292 ALA 292 287 287 ALA ALA B . n 
C 3 293 GLY 293 288 288 GLY GLY B . n 
C 3 294 TYR 294 289 289 TYR TYR B . n 
C 3 295 ASP 295 290 290 ASP ASP B . n 
C 3 296 ASP 296 291 291 ASP ASP B . n 
C 3 297 PHE 297 292 292 PHE PHE B . n 
C 3 298 ASN 298 293 293 ASN ASN B . n 
C 3 299 CYS 299 294 294 CYS CYS B . n 
C 3 300 ASN 300 295 295 ASN ASN B . n 
C 3 301 VAL 301 296 296 VAL VAL B . n 
C 3 302 TRP 302 297 297 TRP TRP B . n 
C 3 303 ASP 303 298 298 ASP ASP B . n 
C 3 304 ALA 304 299 299 ALA ALA B . n 
C 3 305 LEU 305 300 300 LEU LEU B . n 
C 3 306 LYS 306 301 301 LYS LYS B . n 
C 3 307 ALA 307 302 302 ALA ALA B . n 
C 3 308 ASP 308 303 303 ASP ASP B . n 
C 3 309 ARG 309 304 304 ARG ARG B . n 
C 3 310 ALA 310 305 305 ALA ALA B . n 
C 3 311 GLY 311 306 306 GLY GLY B . n 
C 3 312 VAL 312 307 307 VAL VAL B . n 
C 3 313 LEU 313 308 308 LEU LEU B . n 
C 3 314 ALA 314 309 309 ALA ALA B . n 
C 3 315 GLY 315 310 310 GLY GLY B . n 
C 3 316 HIS 316 311 311 HIS HIS B . n 
C 3 317 ASP 317 312 312 ASP ASP B . n 
C 3 318 ASN 318 313 313 ASN ASN B . n 
C 3 319 ARG 319 314 314 ARG ARG B . n 
C 3 320 VAL 320 315 315 VAL VAL B . n 
C 3 321 SER 321 316 316 SER SER B . n 
C 3 322 CYS 322 317 317 CYS CYS B . n 
C 3 323 LEU 323 318 318 LEU LEU B . n 
C 3 324 GLY 324 319 319 GLY GLY B . n 
C 3 325 VAL 325 320 320 VAL VAL B . n 
C 3 326 THR 326 321 321 THR THR B . n 
C 3 327 ASP 327 322 322 ASP ASP B . n 
C 3 328 ASP 328 323 323 ASP ASP B . n 
C 3 329 GLY 329 324 324 GLY GLY B . n 
C 3 330 MET 330 325 325 MET MET B . n 
C 3 331 ALA 331 326 326 ALA ALA B . n 
C 3 332 VAL 332 327 327 VAL VAL B . n 
C 3 333 ALA 333 328 328 ALA ALA B . n 
C 3 334 THR 334 329 329 THR THR B . n 
C 3 335 GLY 335 330 330 GLY GLY B . n 
C 3 336 SER 336 331 331 SER SER B . n 
C 3 337 TRP 337 332 332 TRP TRP B . n 
C 3 338 ASP 338 333 333 ASP ASP B . n 
C 3 339 SER 339 334 334 SER SER B . n 
C 3 340 PHE 340 335 335 PHE PHE B . n 
C 3 341 LEU 341 336 336 LEU LEU B . n 
C 3 342 LYS 342 337 337 LYS LYS B . n 
C 3 343 ILE 343 338 338 ILE ILE B . n 
C 3 344 TRP 344 339 339 TRP TRP B . n 
C 3 345 ASN 345 340 340 ASN ASN B . n 
C 3 346 GLY 346 341 ?   ?   ?   B . n 
C 3 347 ALA 347 342 ?   ?   ?   B . n 
C 3 348 SER 348 343 ?   ?   ?   B . n 
C 3 349 GLY 349 344 ?   ?   ?   B . n 
C 3 350 GLY 350 345 ?   ?   ?   B . n 
C 3 351 GLY 351 346 ?   ?   ?   B . n 
C 3 352 SER 352 347 ?   ?   ?   B . n 
C 3 353 GLY 353 348 ?   ?   ?   B . n 
C 3 354 GLY 354 349 ?   ?   ?   B . n 
C 3 355 ASN 355 350 ?   ?   ?   B . n 
C 3 356 SER 356 351 ?   ?   ?   B . n 
C 3 357 GLY 357 352 ?   ?   ?   B . n 
C 3 358 SER 358 353 ?   ?   ?   B . n 
C 3 359 SER 359 354 ?   ?   ?   B . n 
C 3 360 GLY 360 355 ?   ?   ?   B . n 
C 3 361 GLY 361 356 ?   ?   ?   B . n 
C 3 362 SER 362 357 ?   ?   ?   B . n 
C 3 363 SER 363 358 ?   ?   ?   B . n 
C 3 364 GLY 364 359 ?   ?   ?   B . n 
C 3 365 VAL 365 360 ?   ?   ?   B . n 
C 3 366 SER 366 361 ?   ?   ?   B . n 
C 3 367 GLY 367 362 ?   ?   ?   B . n 
C 3 368 TRP 368 363 ?   ?   ?   B . n 
C 3 369 ARG 369 364 ?   ?   ?   B . n 
C 3 370 LEU 370 365 ?   ?   ?   B . n 
C 3 371 PHE 371 366 ?   ?   ?   B . n 
C 3 372 LYS 372 367 ?   ?   ?   B . n 
C 3 373 LYS 373 368 ?   ?   ?   B . n 
C 3 374 ILE 374 369 ?   ?   ?   B . n 
C 3 375 SER 375 370 ?   ?   ?   B . n 
D 2 1   MET 1   1   ?   ?   ?   G . n 
D 2 2   ALA 2   2   ?   ?   ?   G . n 
D 2 3   SER 3   3   ?   ?   ?   G . n 
D 2 4   ASN 4   4   ?   ?   ?   G . n 
D 2 5   ASN 5   5   ?   ?   ?   G . n 
D 2 6   THR 6   6   ?   ?   ?   G . n 
D 2 7   ALA 7   7   ?   ?   ?   G . n 
D 2 8   SER 8   8   ?   ?   ?   G . n 
D 2 9   ILE 9   9   9   ILE ILE G . n 
D 2 10  ALA 10  10  10  ALA ALA G . n 
D 2 11  GLN 11  11  11  GLN GLN G . n 
D 2 12  ALA 12  12  12  ALA ALA G . n 
D 2 13  ARG 13  13  13  ARG ARG G . n 
D 2 14  LYS 14  14  14  LYS LYS G . n 
D 2 15  LEU 15  15  15  LEU LEU G . n 
D 2 16  VAL 16  16  16  VAL VAL G . n 
D 2 17  GLU 17  17  17  GLU GLU G . n 
D 2 18  GLN 18  18  18  GLN GLN G . n 
D 2 19  LEU 19  19  19  LEU LEU G . n 
D 2 20  LYS 20  20  20  LYS LYS G . n 
D 2 21  MET 21  21  21  MET MET G . n 
D 2 22  GLU 22  22  22  GLU GLU G . n 
D 2 23  ALA 23  23  23  ALA ALA G . n 
D 2 24  ASN 24  24  24  ASN ASN G . n 
D 2 25  ILE 25  25  25  ILE ILE G . n 
D 2 26  ASP 26  26  26  ASP ASP G . n 
D 2 27  ARG 27  27  27  ARG ARG G . n 
D 2 28  ILE 28  28  28  ILE ILE G . n 
D 2 29  LYS 29  29  29  LYS LYS G . n 
D 2 30  VAL 30  30  30  VAL VAL G . n 
D 2 31  SER 31  31  31  SER SER G . n 
D 2 32  LYS 32  32  32  LYS LYS G . n 
D 2 33  ALA 33  33  33  ALA ALA G . n 
D 2 34  ALA 34  34  34  ALA ALA G . n 
D 2 35  ALA 35  35  35  ALA ALA G . n 
D 2 36  ASP 36  36  36  ASP ASP G . n 
D 2 37  LEU 37  37  37  LEU LEU G . n 
D 2 38  MET 38  38  38  MET MET G . n 
D 2 39  ALA 39  39  39  ALA ALA G . n 
D 2 40  TYR 40  40  40  TYR TYR G . n 
D 2 41  CYS 41  41  41  CYS CYS G . n 
D 2 42  GLU 42  42  42  GLU GLU G . n 
D 2 43  ALA 43  43  43  ALA ALA G . n 
D 2 44  HIS 44  44  44  HIS HIS G . n 
D 2 45  ALA 45  45  45  ALA ALA G . n 
D 2 46  LYS 46  46  46  LYS LYS G . n 
D 2 47  GLU 47  47  47  GLU GLU G . n 
D 2 48  ASP 48  48  48  ASP ASP G . n 
D 2 49  PRO 49  49  49  PRO PRO G . n 
D 2 50  LEU 50  50  50  LEU LEU G . n 
D 2 51  LEU 51  51  51  LEU LEU G . n 
D 2 52  THR 52  52  52  THR THR G . n 
D 2 53  PRO 53  53  53  PRO PRO G . n 
D 2 54  VAL 54  54  54  VAL VAL G . n 
D 2 55  PRO 55  55  55  PRO PRO G . n 
D 2 56  ALA 56  56  56  ALA ALA G . n 
D 2 57  SER 57  57  57  SER SER G . n 
D 2 58  GLU 58  58  58  GLU GLU G . n 
D 2 59  ASN 59  59  59  ASN ASN G . n 
D 2 60  PRO 60  60  60  PRO PRO G . n 
D 2 61  PHE 61  61  61  PHE PHE G . n 
D 2 62  ARG 62  62  ?   ?   ?   G . n 
D 2 63  GLU 63  63  ?   ?   ?   G . n 
D 2 64  LYS 64  64  ?   ?   ?   G . n 
D 2 65  LYS 65  65  ?   ?   ?   G . n 
D 2 66  PHE 66  66  ?   ?   ?   G . n 
D 2 67  PHE 67  67  ?   ?   ?   G . n 
D 2 68  CYS 68  68  ?   ?   ?   G . n 
D 2 69  ALA 69  69  ?   ?   ?   G . n 
D 2 70  ILE 70  70  ?   ?   ?   G . n 
D 2 71  LEU 71  71  ?   ?   ?   G . n 
D 2 72  GLY 72  72  ?   ?   ?   G . n 
D 2 73  SER 73  73  ?   ?   ?   G . n 
D 2 74  ALA 74  74  ?   ?   ?   G . n 
D 2 75  GLY 75  75  ?   ?   ?   G . n 
D 2 76  SER 76  76  ?   ?   ?   G . n 
D 2 77  ALA 77  77  ?   ?   ?   G . n 
D 2 78  GLY 78  78  ?   ?   ?   G . n 
D 2 79  SER 79  79  ?   ?   ?   G . n 
D 2 80  ALA 80  80  ?   ?   ?   G . n 
D 2 81  MET 81  81  ?   ?   ?   G . n 
D 2 82  CYS 82  82  ?   ?   ?   G . n 
D 2 83  THR 83  83  ?   ?   ?   G . n 
D 2 84  LEU 84  84  ?   ?   ?   G . n 
D 2 85  SER 85  85  ?   ?   ?   G . n 
D 2 86  ALA 86  86  ?   ?   ?   G . n 
D 2 87  GLU 87  87  ?   ?   ?   G . n 
D 2 88  ASP 88  88  ?   ?   ?   G . n 
D 2 89  LYS 89  89  ?   ?   ?   G . n 
D 2 90  ALA 90  90  ?   ?   ?   G . n 
D 2 91  ALA 91  91  ?   ?   ?   G . n 
D 2 92  VAL 92  92  ?   ?   ?   G . n 
D 2 93  GLU 93  93  ?   ?   ?   G . n 
D 2 94  ARG 94  94  ?   ?   ?   G . n 
D 2 95  SER 95  95  ?   ?   ?   G . n 
D 2 96  LYS 96  96  ?   ?   ?   G . n 
D 2 97  MET 97  97  ?   ?   ?   G . n 
D 2 98  ILE 98  98  ?   ?   ?   G . n 
D 2 99  ASP 99  99  ?   ?   ?   G . n 
D 2 100 ARG 100 100 ?   ?   ?   G . n 
D 2 101 ASN 101 101 ?   ?   ?   G . n 
D 2 102 LEU 102 102 ?   ?   ?   G . n 
D 2 103 ARG 103 103 ?   ?   ?   G . n 
D 2 104 GLU 104 104 ?   ?   ?   G . n 
D 2 105 ASP 105 105 ?   ?   ?   G . n 
D 2 106 GLY 106 106 ?   ?   ?   G . n 
D 2 107 GLU 107 107 ?   ?   ?   G . n 
D 2 108 LYS 108 108 ?   ?   ?   G . n 
D 2 109 ALA 109 109 ?   ?   ?   G . n 
D 2 110 ALA 110 110 ?   ?   ?   G . n 
D 2 111 ARG 111 111 ?   ?   ?   G . n 
D 2 112 GLU 112 112 ?   ?   ?   G . n 
D 2 113 VAL 113 113 ?   ?   ?   G . n 
D 2 114 LYS 114 114 ?   ?   ?   G . n 
D 2 115 LEU 115 115 ?   ?   ?   G . n 
D 2 116 LEU 116 116 ?   ?   ?   G . n 
D 2 117 LEU 117 117 ?   ?   ?   G . n 
D 2 118 LEU 118 118 ?   ?   ?   G . n 
D 2 119 GLY 119 119 ?   ?   ?   G . n 
D 2 120 ALA 120 120 ?   ?   ?   G . n 
D 2 121 GLY 121 121 ?   ?   ?   G . n 
D 2 122 GLU 122 122 ?   ?   ?   G . n 
D 2 123 SER 123 123 ?   ?   ?   G . n 
D 2 124 GLY 124 124 ?   ?   ?   G . n 
D 2 125 LYS 125 125 ?   ?   ?   G . n 
D 2 126 SER 126 126 ?   ?   ?   G . n 
D 2 127 THR 127 127 ?   ?   ?   G . n 
D 2 128 ILE 128 128 ?   ?   ?   G . n 
D 2 129 VAL 129 129 ?   ?   ?   G . n 
D 2 130 LYS 130 130 ?   ?   ?   G . n 
D 2 131 GLN 131 131 ?   ?   ?   G . n 
D 2 132 MET 132 132 ?   ?   ?   G . n 
D 2 133 LYS 133 133 ?   ?   ?   G . n 
D 2 134 ILE 134 134 ?   ?   ?   G . n 
D 2 135 ILE 135 135 ?   ?   ?   G . n 
D 2 136 HIS 136 136 ?   ?   ?   G . n 
D 2 137 GLU 137 137 ?   ?   ?   G . n 
D 2 138 ALA 138 138 ?   ?   ?   G . n 
D 2 139 GLY 139 139 ?   ?   ?   G . n 
D 2 140 TYR 140 140 ?   ?   ?   G . n 
D 2 141 SER 141 141 ?   ?   ?   G . n 
D 2 142 GLU 142 142 ?   ?   ?   G . n 
D 2 143 GLU 143 143 ?   ?   ?   G . n 
D 2 144 GLU 144 144 ?   ?   ?   G . n 
D 2 145 CYS 145 145 ?   ?   ?   G . n 
D 2 146 LYS 146 146 ?   ?   ?   G . n 
D 2 147 GLN 147 147 ?   ?   ?   G . n 
D 2 148 TYR 148 148 ?   ?   ?   G . n 
D 2 149 LYS 149 149 ?   ?   ?   G . n 
D 2 150 ALA 150 150 ?   ?   ?   G . n 
D 2 151 VAL 151 151 ?   ?   ?   G . n 
D 2 152 VAL 152 152 ?   ?   ?   G . n 
D 2 153 TYR 153 153 ?   ?   ?   G . n 
D 2 154 SER 154 154 ?   ?   ?   G . n 
D 2 155 ASN 155 155 ?   ?   ?   G . n 
D 2 156 THR 156 156 ?   ?   ?   G . n 
D 2 157 ILE 157 157 ?   ?   ?   G . n 
D 2 158 GLN 158 158 ?   ?   ?   G . n 
D 2 159 SER 159 159 ?   ?   ?   G . n 
D 2 160 ILE 160 160 ?   ?   ?   G . n 
D 2 161 ILE 161 161 ?   ?   ?   G . n 
D 2 162 ALA 162 162 ?   ?   ?   G . n 
D 2 163 ILE 163 163 ?   ?   ?   G . n 
D 2 164 ILE 164 164 ?   ?   ?   G . n 
D 2 165 ARG 165 165 ?   ?   ?   G . n 
D 2 166 ALA 166 166 ?   ?   ?   G . n 
D 2 167 MET 167 167 ?   ?   ?   G . n 
D 2 168 GLY 168 168 ?   ?   ?   G . n 
D 2 169 ARG 169 169 ?   ?   ?   G . n 
D 2 170 LEU 170 170 ?   ?   ?   G . n 
D 2 171 LYS 171 171 ?   ?   ?   G . n 
D 2 172 ILE 172 172 ?   ?   ?   G . n 
D 2 173 ASP 173 173 ?   ?   ?   G . n 
D 2 174 PHE 174 174 ?   ?   ?   G . n 
D 2 175 GLY 175 175 ?   ?   ?   G . n 
D 2 176 ASP 176 176 ?   ?   ?   G . n 
D 2 177 SER 177 177 ?   ?   ?   G . n 
D 2 178 ALA 178 178 ?   ?   ?   G . n 
D 2 179 ARG 179 179 ?   ?   ?   G . n 
D 2 180 ALA 180 180 ?   ?   ?   G . n 
D 2 181 ASP 181 181 ?   ?   ?   G . n 
D 2 182 ASP 182 182 ?   ?   ?   G . n 
D 2 183 ALA 183 183 ?   ?   ?   G . n 
D 2 184 ARG 184 184 ?   ?   ?   G . n 
D 2 185 GLN 185 185 ?   ?   ?   G . n 
D 2 186 LEU 186 186 ?   ?   ?   G . n 
D 2 187 PHE 187 187 ?   ?   ?   G . n 
D 2 188 VAL 188 188 ?   ?   ?   G . n 
D 2 189 LEU 189 189 ?   ?   ?   G . n 
D 2 190 ALA 190 190 ?   ?   ?   G . n 
D 2 191 GLY 191 191 ?   ?   ?   G . n 
D 2 192 ALA 192 192 ?   ?   ?   G . n 
D 2 193 ALA 193 193 ?   ?   ?   G . n 
D 2 194 GLU 194 194 ?   ?   ?   G . n 
D 2 195 GLU 195 195 ?   ?   ?   G . n 
D 2 196 GLY 196 196 ?   ?   ?   G . n 
D 2 197 PHE 197 197 ?   ?   ?   G . n 
D 2 198 MET 198 198 ?   ?   ?   G . n 
D 2 199 THR 199 199 ?   ?   ?   G . n 
D 2 200 ALA 200 200 ?   ?   ?   G . n 
D 2 201 GLU 201 201 ?   ?   ?   G . n 
D 2 202 LEU 202 202 ?   ?   ?   G . n 
D 2 203 ALA 203 203 ?   ?   ?   G . n 
D 2 204 GLY 204 204 ?   ?   ?   G . n 
D 2 205 VAL 205 205 ?   ?   ?   G . n 
D 2 206 ILE 206 206 ?   ?   ?   G . n 
D 2 207 LYS 207 207 ?   ?   ?   G . n 
D 2 208 ARG 208 208 ?   ?   ?   G . n 
D 2 209 LEU 209 209 ?   ?   ?   G . n 
D 2 210 TRP 210 210 ?   ?   ?   G . n 
D 2 211 LYS 211 211 ?   ?   ?   G . n 
D 2 212 ASP 212 212 ?   ?   ?   G . n 
D 2 213 SER 213 213 ?   ?   ?   G . n 
D 2 214 GLY 214 214 ?   ?   ?   G . n 
D 2 215 VAL 215 215 ?   ?   ?   G . n 
D 2 216 GLN 216 216 ?   ?   ?   G . n 
D 2 217 ALA 217 217 ?   ?   ?   G . n 
D 2 218 CYS 218 218 ?   ?   ?   G . n 
D 2 219 PHE 219 219 ?   ?   ?   G . n 
D 2 220 ASN 220 220 ?   ?   ?   G . n 
D 2 221 ARG 221 221 ?   ?   ?   G . n 
D 2 222 SER 222 222 ?   ?   ?   G . n 
D 2 223 ARG 223 223 ?   ?   ?   G . n 
D 2 224 GLU 224 224 ?   ?   ?   G . n 
D 2 225 TYR 225 225 ?   ?   ?   G . n 
D 2 226 GLN 226 226 ?   ?   ?   G . n 
D 2 227 LEU 227 227 ?   ?   ?   G . n 
D 2 228 ASN 228 228 ?   ?   ?   G . n 
D 2 229 ASP 229 229 ?   ?   ?   G . n 
D 2 230 SER 230 230 ?   ?   ?   G . n 
D 2 231 ALA 231 231 ?   ?   ?   G . n 
D 2 232 ALA 232 232 ?   ?   ?   G . n 
D 2 233 TYR 233 233 ?   ?   ?   G . n 
D 2 234 TYR 234 234 ?   ?   ?   G . n 
D 2 235 LEU 235 235 ?   ?   ?   G . n 
D 2 236 ASN 236 236 ?   ?   ?   G . n 
D 2 237 ASP 237 237 ?   ?   ?   G . n 
D 2 238 LEU 238 238 ?   ?   ?   G . n 
D 2 239 ASP 239 239 ?   ?   ?   G . n 
D 2 240 ARG 240 240 ?   ?   ?   G . n 
D 2 241 ILE 241 241 ?   ?   ?   G . n 
D 2 242 ALA 242 242 ?   ?   ?   G . n 
D 2 243 GLN 243 243 ?   ?   ?   G . n 
D 2 244 PRO 244 244 ?   ?   ?   G . n 
D 2 245 ASN 245 245 ?   ?   ?   G . n 
D 2 246 TYR 246 246 ?   ?   ?   G . n 
D 2 247 ILE 247 247 ?   ?   ?   G . n 
D 2 248 PRO 248 248 ?   ?   ?   G . n 
D 2 249 THR 249 249 ?   ?   ?   G . n 
D 2 250 GLN 250 250 ?   ?   ?   G . n 
D 2 251 GLN 251 251 ?   ?   ?   G . n 
D 2 252 ASP 252 252 ?   ?   ?   G . n 
D 2 253 VAL 253 253 ?   ?   ?   G . n 
D 2 254 LEU 254 254 ?   ?   ?   G . n 
D 2 255 ARG 255 255 ?   ?   ?   G . n 
D 2 256 THR 256 256 ?   ?   ?   G . n 
D 2 257 ARG 257 257 ?   ?   ?   G . n 
D 2 258 VAL 258 258 ?   ?   ?   G . n 
D 2 259 LYS 259 259 ?   ?   ?   G . n 
D 2 260 THR 260 260 ?   ?   ?   G . n 
D 2 261 THR 261 261 ?   ?   ?   G . n 
D 2 262 GLY 262 262 ?   ?   ?   G . n 
D 2 263 ILE 263 263 ?   ?   ?   G . n 
D 2 264 VAL 264 264 ?   ?   ?   G . n 
D 2 265 GLU 265 265 ?   ?   ?   G . n 
D 2 266 THR 266 266 ?   ?   ?   G . n 
D 2 267 HIS 267 267 ?   ?   ?   G . n 
D 2 268 PHE 268 268 ?   ?   ?   G . n 
D 2 269 THR 269 269 ?   ?   ?   G . n 
D 2 270 PHE 270 270 ?   ?   ?   G . n 
D 2 271 LYS 271 271 ?   ?   ?   G . n 
D 2 272 ASP 272 272 ?   ?   ?   G . n 
D 2 273 LEU 273 273 ?   ?   ?   G . n 
D 2 274 HIS 274 274 ?   ?   ?   G . n 
D 2 275 PHE 275 275 ?   ?   ?   G . n 
D 2 276 LYS 276 276 ?   ?   ?   G . n 
D 2 277 MET 277 277 ?   ?   ?   G . n 
D 2 278 PHE 278 278 ?   ?   ?   G . n 
D 2 279 ASP 279 279 ?   ?   ?   G . n 
D 2 280 VAL 280 280 ?   ?   ?   G . n 
D 2 281 GLY 281 281 ?   ?   ?   G . n 
D 2 282 GLY 282 282 ?   ?   ?   G . n 
D 2 283 GLN 283 283 ?   ?   ?   G . n 
D 2 284 ARG 284 284 ?   ?   ?   G . n 
D 2 285 SER 285 285 ?   ?   ?   G . n 
D 2 286 GLU 286 286 ?   ?   ?   G . n 
D 2 287 ARG 287 287 ?   ?   ?   G . n 
D 2 288 LYS 288 288 ?   ?   ?   G . n 
D 2 289 LYS 289 289 ?   ?   ?   G . n 
D 2 290 TRP 290 290 ?   ?   ?   G . n 
D 2 291 ILE 291 291 ?   ?   ?   G . n 
D 2 292 HIS 292 292 ?   ?   ?   G . n 
D 2 293 CYS 293 293 ?   ?   ?   G . n 
D 2 294 PHE 294 294 ?   ?   ?   G . n 
D 2 295 GLU 295 295 ?   ?   ?   G . n 
D 2 296 GLY 296 296 ?   ?   ?   G . n 
D 2 297 VAL 297 297 ?   ?   ?   G . n 
D 2 298 THR 298 298 ?   ?   ?   G . n 
D 2 299 ALA 299 299 ?   ?   ?   G . n 
D 2 300 ILE 300 300 ?   ?   ?   G . n 
D 2 301 ILE 301 301 ?   ?   ?   G . n 
D 2 302 PHE 302 302 ?   ?   ?   G . n 
D 2 303 CYS 303 303 ?   ?   ?   G . n 
D 2 304 VAL 304 304 ?   ?   ?   G . n 
D 2 305 ALA 305 305 ?   ?   ?   G . n 
D 2 306 LEU 306 306 ?   ?   ?   G . n 
D 2 307 SER 307 307 ?   ?   ?   G . n 
D 2 308 ASP 308 308 ?   ?   ?   G . n 
D 2 309 TYR 309 309 ?   ?   ?   G . n 
D 2 310 ASP 310 310 ?   ?   ?   G . n 
D 2 311 LEU 311 311 ?   ?   ?   G . n 
D 2 312 VAL 312 312 ?   ?   ?   G . n 
D 2 313 LEU 313 313 ?   ?   ?   G . n 
D 2 314 ALA 314 314 ?   ?   ?   G . n 
D 2 315 GLU 315 315 ?   ?   ?   G . n 
D 2 316 ASP 316 316 ?   ?   ?   G . n 
D 2 317 GLU 317 317 ?   ?   ?   G . n 
D 2 318 GLU 318 318 ?   ?   ?   G . n 
D 2 319 MET 319 319 ?   ?   ?   G . n 
D 2 320 ASN 320 320 ?   ?   ?   G . n 
D 2 321 ARG 321 321 ?   ?   ?   G . n 
D 2 322 MET 322 322 ?   ?   ?   G . n 
D 2 323 HIS 323 323 ?   ?   ?   G . n 
D 2 324 GLU 324 324 ?   ?   ?   G . n 
D 2 325 SER 325 325 ?   ?   ?   G . n 
D 2 326 MET 326 326 ?   ?   ?   G . n 
D 2 327 LYS 327 327 ?   ?   ?   G . n 
D 2 328 LEU 328 328 ?   ?   ?   G . n 
D 2 329 PHE 329 329 ?   ?   ?   G . n 
D 2 330 ASP 330 330 ?   ?   ?   G . n 
D 2 331 SER 331 331 ?   ?   ?   G . n 
D 2 332 ILE 332 332 ?   ?   ?   G . n 
D 2 333 CYS 333 333 ?   ?   ?   G . n 
D 2 334 ASN 334 334 ?   ?   ?   G . n 
D 2 335 ASN 335 335 ?   ?   ?   G . n 
D 2 336 LYS 336 336 ?   ?   ?   G . n 
D 2 337 TRP 337 337 ?   ?   ?   G . n 
D 2 338 PHE 338 338 ?   ?   ?   G . n 
D 2 339 THR 339 339 ?   ?   ?   G . n 
D 2 340 ASP 340 340 ?   ?   ?   G . n 
D 2 341 THR 341 341 ?   ?   ?   G . n 
D 2 342 SER 342 342 ?   ?   ?   G . n 
D 2 343 ILE 343 343 ?   ?   ?   G . n 
D 2 344 ILE 344 344 ?   ?   ?   G . n 
D 2 345 LEU 345 345 ?   ?   ?   G . n 
D 2 346 PHE 346 346 ?   ?   ?   G . n 
D 2 347 LEU 347 347 ?   ?   ?   G . n 
D 2 348 ASN 348 348 ?   ?   ?   G . n 
D 2 349 LYS 349 349 ?   ?   ?   G . n 
D 2 350 LYS 350 350 ?   ?   ?   G . n 
D 2 351 ASP 351 351 ?   ?   ?   G . n 
D 2 352 LEU 352 352 ?   ?   ?   G . n 
D 2 353 PHE 353 353 ?   ?   ?   G . n 
D 2 354 GLU 354 354 ?   ?   ?   G . n 
D 2 355 GLU 355 355 ?   ?   ?   G . n 
D 2 356 LYS 356 356 ?   ?   ?   G . n 
D 2 357 ILE 357 357 ?   ?   ?   G . n 
D 2 358 LYS 358 358 ?   ?   ?   G . n 
D 2 359 LYS 359 359 ?   ?   ?   G . n 
D 2 360 SER 360 360 ?   ?   ?   G . n 
D 2 361 PRO 361 361 ?   ?   ?   G . n 
D 2 362 LEU 362 362 ?   ?   ?   G . n 
D 2 363 THR 363 363 ?   ?   ?   G . n 
D 2 364 ILE 364 364 ?   ?   ?   G . n 
D 2 365 CYS 365 365 ?   ?   ?   G . n 
D 2 366 TYR 366 366 ?   ?   ?   G . n 
D 2 367 PRO 367 367 ?   ?   ?   G . n 
D 2 368 GLU 368 368 ?   ?   ?   G . n 
D 2 369 TYR 369 369 ?   ?   ?   G . n 
D 2 370 ALA 370 370 ?   ?   ?   G . n 
D 2 371 GLY 371 371 ?   ?   ?   G . n 
D 2 372 SER 372 372 ?   ?   ?   G . n 
D 2 373 ASN 373 373 ?   ?   ?   G . n 
D 2 374 THR 374 374 ?   ?   ?   G . n 
D 2 375 TYR 375 375 ?   ?   ?   G . n 
D 2 376 GLU 376 376 ?   ?   ?   G . n 
D 2 377 GLU 377 377 ?   ?   ?   G . n 
D 2 378 ALA 378 378 ?   ?   ?   G . n 
D 2 379 ALA 379 379 ?   ?   ?   G . n 
D 2 380 ALA 380 380 ?   ?   ?   G . n 
D 2 381 TYR 381 381 ?   ?   ?   G . n 
D 2 382 ILE 382 382 ?   ?   ?   G . n 
D 2 383 GLN 383 383 ?   ?   ?   G . n 
D 2 384 CYS 384 384 ?   ?   ?   G . n 
D 2 385 GLN 385 385 ?   ?   ?   G . n 
D 2 386 PHE 386 386 ?   ?   ?   G . n 
D 2 387 GLU 387 387 ?   ?   ?   G . n 
D 2 388 ASP 388 388 ?   ?   ?   G . n 
D 2 389 LEU 389 389 ?   ?   ?   G . n 
D 2 390 ASN 390 390 ?   ?   ?   G . n 
D 2 391 LYS 391 391 ?   ?   ?   G . n 
D 2 392 ARG 392 392 ?   ?   ?   G . n 
D 2 393 LYS 393 393 ?   ?   ?   G . n 
D 2 394 ASP 394 394 ?   ?   ?   G . n 
D 2 395 THR 395 395 ?   ?   ?   G . n 
D 2 396 LYS 396 396 ?   ?   ?   G . n 
D 2 397 GLU 397 397 ?   ?   ?   G . n 
D 2 398 ILE 398 398 ?   ?   ?   G . n 
D 2 399 TYR 399 399 ?   ?   ?   G . n 
D 2 400 THR 400 400 ?   ?   ?   G . n 
D 2 401 HIS 401 401 ?   ?   ?   G . n 
D 2 402 PHE 402 402 ?   ?   ?   G . n 
D 2 403 THR 403 403 ?   ?   ?   G . n 
D 2 404 CYS 404 404 ?   ?   ?   G . n 
D 2 405 ALA 405 405 ?   ?   ?   G . n 
D 2 406 THR 406 406 ?   ?   ?   G . n 
D 2 407 ASP 407 407 ?   ?   ?   G . n 
D 2 408 THR 408 408 ?   ?   ?   G . n 
D 2 409 LYS 409 409 ?   ?   ?   G . n 
D 2 410 ASN 410 410 ?   ?   ?   G . n 
D 2 411 VAL 411 411 ?   ?   ?   G . n 
D 2 412 GLN 412 412 ?   ?   ?   G . n 
D 2 413 PHE 413 413 ?   ?   ?   G . n 
D 2 414 VAL 414 414 ?   ?   ?   G . n 
D 2 415 PHE 415 415 ?   ?   ?   G . n 
D 2 416 ASP 416 416 ?   ?   ?   G . n 
D 2 417 ALA 417 417 ?   ?   ?   G . n 
D 2 418 VAL 418 418 ?   ?   ?   G . n 
D 2 419 THR 419 419 ?   ?   ?   G . n 
D 2 420 ASP 420 420 ?   ?   ?   G . n 
D 2 421 VAL 421 421 ?   ?   ?   G . n 
D 2 422 ILE 422 422 ?   ?   ?   G . n 
D 2 423 ILE 423 423 ?   ?   ?   G . n 
D 2 424 LYS 424 424 ?   ?   ?   G . n 
D 2 425 ASN 425 425 ?   ?   ?   G . n 
D 2 426 ASN 426 426 ?   ?   ?   G . n 
D 2 427 LEU 427 427 ?   ?   ?   G . n 
D 2 428 LYS 428 428 ?   ?   ?   G . n 
D 2 429 ASP 429 429 ?   ?   ?   G . n 
D 2 430 CYS 430 430 ?   ?   ?   G . n 
D 2 431 GLY 431 431 ?   ?   ?   G . n 
D 2 432 LEU 432 432 ?   ?   ?   G . n 
D 2 433 PHE 433 433 ?   ?   ?   G . n 
E 4 1   ASP 1   1   ?   ?   ?   S . n 
E 4 2   VAL 2   2   2   VAL VAL S . n 
E 4 3   GLN 3   3   3   GLN GLN S . n 
E 4 4   LEU 4   4   4   LEU LEU S . n 
E 4 5   VAL 5   5   5   VAL VAL S . n 
E 4 6   GLU 6   6   6   GLU GLU S . n 
E 4 7   SER 7   7   7   SER SER S . n 
E 4 8   GLY 8   8   8   GLY GLY S . n 
E 4 9   GLY 9   9   9   GLY GLY S . n 
E 4 10  GLY 10  10  10  GLY GLY S . n 
E 4 11  LEU 11  11  11  LEU LEU S . n 
E 4 12  VAL 12  12  12  VAL VAL S . n 
E 4 13  GLN 13  13  13  GLN GLN S . n 
E 4 14  PRO 14  14  14  PRO PRO S . n 
E 4 15  GLY 15  15  15  GLY GLY S . n 
E 4 16  GLY 16  16  16  GLY GLY S . n 
E 4 17  SER 17  17  17  SER SER S . n 
E 4 18  ARG 18  18  18  ARG ARG S . n 
E 4 19  LYS 19  19  19  LYS LYS S . n 
E 4 20  LEU 20  20  20  LEU LEU S . n 
E 4 21  SER 21  21  21  SER SER S . n 
E 4 22  CYS 22  22  22  CYS CYS S . n 
E 4 23  SER 23  23  23  SER SER S . n 
E 4 24  ALA 24  24  24  ALA ALA S . n 
E 4 25  SER 25  25  25  SER SER S . n 
E 4 26  GLY 26  26  26  GLY GLY S . n 
E 4 27  PHE 27  27  27  PHE PHE S . n 
E 4 28  ALA 28  28  28  ALA ALA S . n 
E 4 29  PHE 29  29  29  PHE PHE S . n 
E 4 30  SER 30  30  30  SER SER S . n 
E 4 31  SER 31  31  31  SER SER S . n 
E 4 32  PHE 32  32  32  PHE PHE S . n 
E 4 33  GLY 33  33  33  GLY GLY S . n 
E 4 34  MET 34  34  34  MET MET S . n 
E 4 35  HIS 35  35  35  HIS HIS S . n 
E 4 36  TRP 36  36  36  TRP TRP S . n 
E 4 37  VAL 37  37  37  VAL VAL S . n 
E 4 38  ARG 38  38  38  ARG ARG S . n 
E 4 39  GLN 39  39  39  GLN GLN S . n 
E 4 40  ALA 40  40  40  ALA ALA S . n 
E 4 41  PRO 41  41  41  PRO PRO S . n 
E 4 42  GLU 42  42  42  GLU GLU S . n 
E 4 43  LYS 43  43  43  LYS LYS S . n 
E 4 44  GLY 44  44  44  GLY GLY S . n 
E 4 45  LEU 45  45  45  LEU LEU S . n 
E 4 46  GLU 46  46  46  GLU GLU S . n 
E 4 47  TRP 47  47  47  TRP TRP S . n 
E 4 48  VAL 48  48  48  VAL VAL S . n 
E 4 49  ALA 49  49  49  ALA ALA S . n 
E 4 50  TYR 50  50  50  TYR TYR S . n 
E 4 51  ILE 51  51  51  ILE ILE S . n 
E 4 52  SER 52  52  52  SER SER S . n 
E 4 53  SER 53  53  53  SER SER S . n 
E 4 54  GLY 54  54  54  GLY GLY S . n 
E 4 55  SER 55  55  55  SER SER S . n 
E 4 56  GLY 56  56  56  GLY GLY S . n 
E 4 57  THR 57  57  57  THR THR S . n 
E 4 58  ILE 58  58  58  ILE ILE S . n 
E 4 59  TYR 59  59  59  TYR TYR S . n 
E 4 60  TYR 60  60  60  TYR TYR S . n 
E 4 61  ALA 61  61  61  ALA ALA S . n 
E 4 62  ASP 62  62  62  ASP ASP S . n 
E 4 63  THR 63  63  63  THR THR S . n 
E 4 64  VAL 64  64  64  VAL VAL S . n 
E 4 65  LYS 65  65  65  LYS LYS S . n 
E 4 66  GLY 66  66  66  GLY GLY S . n 
E 4 67  ARG 67  67  67  ARG ARG S . n 
E 4 68  PHE 68  68  68  PHE PHE S . n 
E 4 69  THR 69  69  69  THR THR S . n 
E 4 70  ILE 70  70  70  ILE ILE S . n 
E 4 71  SER 71  71  71  SER SER S . n 
E 4 72  ARG 72  72  72  ARG ARG S . n 
E 4 73  ASP 73  73  73  ASP ASP S . n 
E 4 74  ASP 74  74  74  ASP ASP S . n 
E 4 75  PRO 75  75  75  PRO PRO S . n 
E 4 76  LYS 76  76  76  LYS LYS S . n 
E 4 77  ASN 77  77  77  ASN ASN S . n 
E 4 78  THR 78  78  78  THR THR S . n 
E 4 79  LEU 79  79  79  LEU LEU S . n 
E 4 80  PHE 80  80  80  PHE PHE S . n 
E 4 81  LEU 81  81  81  LEU LEU S . n 
E 4 82  GLN 82  82  82  GLN GLN S . n 
E 4 83  MET 83  83  83  MET MET S . n 
E 4 84  THR 84  84  84  THR THR S . n 
E 4 85  SER 85  85  85  SER SER S . n 
E 4 86  LEU 86  86  86  LEU LEU S . n 
E 4 87  ARG 87  87  87  ARG ARG S . n 
E 4 88  SER 88  88  88  SER SER S . n 
E 4 89  GLU 89  89  89  GLU GLU S . n 
E 4 90  ASP 90  90  90  ASP ASP S . n 
E 4 91  THR 91  91  91  THR THR S . n 
E 4 92  ALA 92  92  92  ALA ALA S . n 
E 4 93  MET 93  93  93  MET MET S . n 
E 4 94  TYR 94  94  94  TYR TYR S . n 
E 4 95  TYR 95  95  95  TYR TYR S . n 
E 4 96  CYS 96  96  96  CYS CYS S . n 
E 4 97  VAL 97  97  97  VAL VAL S . n 
E 4 98  ARG 98  98  98  ARG ARG S . n 
E 4 99  SER 99  99  99  SER SER S . n 
E 4 100 ILE 100 100 100 ILE ILE S . n 
E 4 101 TYR 101 101 101 TYR TYR S . n 
E 4 102 TYR 102 102 102 TYR TYR S . n 
E 4 103 TYR 103 103 103 TYR TYR S . n 
E 4 104 GLY 104 104 104 GLY GLY S . n 
E 4 105 SER 105 105 105 SER SER S . n 
E 4 106 SER 106 106 106 SER SER S . n 
E 4 107 PRO 107 107 107 PRO PRO S . n 
E 4 108 PHE 108 108 108 PHE PHE S . n 
E 4 109 ASP 109 109 109 ASP ASP S . n 
E 4 110 PHE 110 110 110 PHE PHE S . n 
E 4 111 TRP 111 111 111 TRP TRP S . n 
E 4 112 GLY 112 112 112 GLY GLY S . n 
E 4 113 GLN 113 113 113 GLN GLN S . n 
E 4 114 GLY 114 114 114 GLY GLY S . n 
E 4 115 THR 115 115 115 THR THR S . n 
E 4 116 THR 116 116 116 THR THR S . n 
E 4 117 LEU 117 117 117 LEU LEU S . n 
E 4 118 THR 118 118 118 THR THR S . n 
E 4 119 VAL 119 119 119 VAL VAL S . n 
E 4 120 SER 120 120 120 SER SER S . n 
E 4 121 SER 121 121 121 SER SER S . n 
E 4 122 GLY 122 121 ?   ?   ?   S A n 
E 4 123 GLY 123 121 ?   ?   ?   S B n 
E 4 124 GLY 124 121 ?   ?   ?   S C n 
E 4 125 GLY 125 121 ?   ?   ?   S D n 
E 4 126 SER 126 121 ?   ?   ?   S E n 
E 4 127 GLY 127 121 ?   ?   ?   S F n 
E 4 128 GLY 128 121 ?   ?   ?   S G n 
E 4 129 GLY 129 121 ?   ?   ?   S H n 
E 4 130 GLY 130 121 ?   ?   ?   S I n 
E 4 131 SER 131 121 ?   ?   ?   S J n 
E 4 132 GLY 132 121 ?   ?   ?   S K n 
E 4 133 GLY 133 121 ?   ?   ?   S L n 
E 4 134 GLY 134 121 ?   ?   ?   S M n 
E 4 135 GLY 135 121 ?   ?   ?   S N n 
E 4 136 SER 136 124 124 SER SER S . n 
E 4 137 ASP 137 125 125 ASP ASP S . n 
E 4 138 ILE 138 126 126 ILE ILE S . n 
E 4 139 VAL 139 127 127 VAL VAL S . n 
E 4 140 MET 140 128 128 MET MET S . n 
E 4 141 THR 141 129 129 THR THR S . n 
E 4 142 GLN 142 130 130 GLN GLN S . n 
E 4 143 ALA 143 131 131 ALA ALA S . n 
E 4 144 THR 144 132 132 THR THR S . n 
E 4 145 SER 145 133 133 SER SER S . n 
E 4 146 SER 146 134 134 SER SER S . n 
E 4 147 VAL 147 135 135 VAL VAL S . n 
E 4 148 PRO 148 136 136 PRO PRO S . n 
E 4 149 VAL 149 137 137 VAL VAL S . n 
E 4 150 THR 150 138 138 THR THR S . n 
E 4 151 PRO 151 139 139 PRO PRO S . n 
E 4 152 GLY 152 140 140 GLY GLY S . n 
E 4 153 GLU 153 141 141 GLU GLU S . n 
E 4 154 SER 154 142 142 SER SER S . n 
E 4 155 VAL 155 143 143 VAL VAL S . n 
E 4 156 SER 156 144 144 SER SER S . n 
E 4 157 ILE 157 145 145 ILE ILE S . n 
E 4 158 SER 158 146 146 SER SER S . n 
E 4 159 CYS 159 147 147 CYS CYS S . n 
E 4 160 ARG 160 148 148 ARG ARG S . n 
E 4 161 SER 161 149 149 SER SER S . n 
E 4 162 SER 162 150 150 SER SER S . n 
E 4 163 LYS 163 151 151 LYS LYS S . n 
E 4 164 SER 164 152 152 SER SER S . n 
E 4 165 LEU 165 153 153 LEU LEU S . n 
E 4 166 LEU 166 154 154 LEU LEU S . n 
E 4 167 HIS 167 155 155 HIS HIS S . n 
E 4 168 SER 168 156 156 SER SER S . n 
E 4 169 ASN 169 157 157 ASN ASN S . n 
E 4 170 GLY 170 158 158 GLY GLY S . n 
E 4 171 ASN 171 159 159 ASN ASN S . n 
E 4 172 THR 172 160 160 THR THR S . n 
E 4 173 TYR 173 161 161 TYR TYR S . n 
E 4 174 LEU 174 162 162 LEU LEU S . n 
E 4 175 TYR 175 163 163 TYR TYR S . n 
E 4 176 TRP 176 164 164 TRP TRP S . n 
E 4 177 PHE 177 165 165 PHE PHE S . n 
E 4 178 LEU 178 166 166 LEU LEU S . n 
E 4 179 GLN 179 167 167 GLN GLN S . n 
E 4 180 ARG 180 168 168 ARG ARG S . n 
E 4 181 PRO 181 169 169 PRO PRO S . n 
E 4 182 GLY 182 170 170 GLY GLY S . n 
E 4 183 GLN 183 171 171 GLN GLN S . n 
E 4 184 SER 184 172 172 SER SER S . n 
E 4 185 PRO 185 173 173 PRO PRO S . n 
E 4 186 GLN 186 174 174 GLN GLN S . n 
E 4 187 LEU 187 175 175 LEU LEU S . n 
E 4 188 LEU 188 176 176 LEU LEU S . n 
E 4 189 ILE 189 177 177 ILE ILE S . n 
E 4 190 TYR 190 178 178 TYR TYR S . n 
E 4 191 ARG 191 179 179 ARG ARG S . n 
E 4 192 MET 192 180 180 MET MET S . n 
E 4 193 SER 193 181 181 SER SER S . n 
E 4 194 ASN 194 182 182 ASN ASN S . n 
E 4 195 LEU 195 183 183 LEU LEU S . n 
E 4 196 ALA 196 184 184 ALA ALA S . n 
E 4 197 SER 197 185 185 SER SER S . n 
E 4 198 GLY 198 186 186 GLY GLY S . n 
E 4 199 VAL 199 187 187 VAL VAL S . n 
E 4 200 PRO 200 188 188 PRO PRO S . n 
E 4 201 ASP 201 189 189 ASP ASP S . n 
E 4 202 ARG 202 190 190 ARG ARG S . n 
E 4 203 PHE 203 191 191 PHE PHE S . n 
E 4 204 SER 204 192 192 SER SER S . n 
E 4 205 GLY 205 193 193 GLY GLY S . n 
E 4 206 SER 206 194 194 SER SER S . n 
E 4 207 GLY 207 195 195 GLY GLY S . n 
E 4 208 SER 208 196 196 SER SER S . n 
E 4 209 GLY 209 197 197 GLY GLY S . n 
E 4 210 THR 210 198 198 THR THR S . n 
E 4 211 ALA 211 199 199 ALA ALA S . n 
E 4 212 PHE 212 200 200 PHE PHE S . n 
E 4 213 THR 213 201 201 THR THR S . n 
E 4 214 LEU 214 202 202 LEU LEU S . n 
E 4 215 THR 215 203 203 THR THR S . n 
E 4 216 ILE 216 204 204 ILE ILE S . n 
E 4 217 SER 217 205 205 SER SER S . n 
E 4 218 ARG 218 206 206 ARG ARG S . n 
E 4 219 LEU 219 207 207 LEU LEU S . n 
E 4 220 GLU 220 208 208 GLU GLU S . n 
E 4 221 ALA 221 209 209 ALA ALA S . n 
E 4 222 GLU 222 210 210 GLU GLU S . n 
E 4 223 ASP 223 211 211 ASP ASP S . n 
E 4 224 VAL 224 212 212 VAL VAL S . n 
E 4 225 GLY 225 213 213 GLY GLY S . n 
E 4 226 VAL 226 214 214 VAL VAL S . n 
E 4 227 TYR 227 215 215 TYR TYR S . n 
E 4 228 TYR 228 216 216 TYR TYR S . n 
E 4 229 CYS 229 217 217 CYS CYS S . n 
E 4 230 MET 230 218 218 MET MET S . n 
E 4 231 GLN 231 219 219 GLN GLN S . n 
E 4 232 HIS 232 220 220 HIS HIS S . n 
E 4 233 LEU 233 221 221 LEU LEU S . n 
E 4 234 GLU 234 222 222 GLU GLU S . n 
E 4 235 TYR 235 223 223 TYR TYR S . n 
E 4 236 PRO 236 224 224 PRO PRO S . n 
E 4 237 LEU 237 225 225 LEU LEU S . n 
E 4 238 THR 238 226 226 THR THR S . n 
E 4 239 PHE 239 227 227 PHE PHE S . n 
E 4 240 GLY 240 228 228 GLY GLY S . n 
E 4 241 ALA 241 229 229 ALA ALA S . n 
E 4 242 GLY 242 230 230 GLY GLY S . n 
E 4 243 THR 243 231 231 THR THR S . n 
E 4 244 LYS 244 232 232 LYS LYS S . n 
E 4 245 LEU 245 233 233 LEU LEU S . n 
E 4 246 GLU 246 234 234 GLU GLU S . n 
E 4 247 LEU 247 235 235 LEU LEU S . n 
E 4 248 LYS 248 236 ?   ?   ?   S . n 
E 4 249 ALA 249 237 ?   ?   ?   S . n 
E 4 250 ALA 250 238 ?   ?   ?   S . n 
E 4 251 ALA 251 239 ?   ?   ?   S . n 
E 4 252 ALA 252 240 ?   ?   ?   S . n 
E 4 253 SER 253 241 ?   ?   ?   S . n 
E 4 254 SER 254 242 ?   ?   ?   S . n 
E 4 255 GLU 255 243 ?   ?   ?   S . n 
E 4 256 ASP 256 244 ?   ?   ?   S . n 
E 4 257 LEU 257 245 ?   ?   ?   S . n 
E 4 258 TYR 258 246 ?   ?   ?   S . n 
E 4 259 PHE 259 247 ?   ?   ?   S . n 
E 4 260 GLN 260 248 ?   ?   ?   S . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NEC 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NEC 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       5 
_pdbx_nonpoly_scheme.mon_id          NEC 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     801 
_pdbx_nonpoly_scheme.auth_seq_num    400 
_pdbx_nonpoly_scheme.pdb_mon_id      NEC 
_pdbx_nonpoly_scheme.auth_mon_id     NEC 
_pdbx_nonpoly_scheme.pdb_strand_id   R 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8YH0 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8YH0 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8YH0 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8YH0 
_struct.title                        'A3R-Gi complex bound to NECA' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8YH0 
_struct_keywords.text            'GPCR, complex, adenosine receptor, adenosine, g protein, SIGNALING PROTEIN' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 2 ? 
E N N 4 ? 
F N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP HEMA_I75A3      P03435     ? 1 MKTIIALSYIFCLVFA 1   
2 UNP W5QED6_SHEEP    W5QED6     ? 1 
;PVNSTAVSWTSVTYITVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVISLGVTIHFY
SCLFMTCLMLIFTHASIMSLLAIAVDRYLRVKLTVRYRRVTTQRRIWLALGLCWLVSFLVGLTPMFGWNMKLSSADENLT
FLPCRFRSVMRMDYMVYFSFFLWILVPLVVMCAIYFDIFYIIRNRLSQSFSGSRETGAFYGREFKTAKSLLLVLFLFALC
WLPLSIINCILYFDGQVPQTVLYLGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVICQPSKSMDPSTEQTSE
;
2   
3 PDB 8YH0            8YH0       ? 1 ? 357 
4 UNP A0A5P9VSM6_HRSV A0A5P9VSM6 ? 1 
;VSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQ
HDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNG
IKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSKLSKDPNEKRDHMVLLEFVTAAGITLGMDELYK
;
2   
5 UNP GBG2_HUMAN      P59768     ? 2 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1   
6 UNP GNAI1_HUMAN     P63096     ? 2 
;CTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSII
AIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRI
AQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNR
MHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTH
FTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
3   
7 UNP GBB1_BOVIN      P62871     ? 3 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2   
8 PDB 8YH0            8YH0       ? 4 ? 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1  1 8YH0 R 1   ? 16  ? P03435     1   ? 16  ? -24 -9  
2  2 8YH0 R 27  ? 342 ? W5QED6     2   ? 317 ? 2   317 
3  3 8YH0 R 357 ? 514 ? 8YH0       332 ? 489 ? 332 489 
4  4 8YH0 R 544 ? 781 ? A0A5P9VSM6 2   ? 239 ? 519 756 
5  5 8YH0 A 1   ? 71  ? P59768     1   ? 71  ? -78 -8  
6  6 8YH0 A 82  ? 433 ? P63096     3   ? 354 ? 3   354 
7  7 8YH0 B 7   ? 345 ? P62871     2   ? 340 ? 2   340 
8  5 8YH0 G 1   ? 71  ? P59768     1   ? 71  ? 1   71  
9  6 8YH0 G 82  ? 433 ? P63096     3   ? 354 ? 82  433 
10 8 8YH0 S 1   ? 260 ? 8YH0       1   ? 248 ? 1   248 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8YH0 ASP R 17  ? UNP P03435     ? ? linker                  -8  1   
1 8YH0 TYR R 18  ? UNP P03435     ? ? linker                  -7  2   
1 8YH0 LYS R 19  ? UNP P03435     ? ? linker                  -6  3   
1 8YH0 ASP R 20  ? UNP P03435     ? ? linker                  -5  4   
1 8YH0 ASP R 21  ? UNP P03435     ? ? linker                  -4  5   
1 8YH0 ASP R 22  ? UNP P03435     ? ? linker                  -3  6   
1 8YH0 ASP R 23  ? UNP P03435     ? ? linker                  -2  7   
1 8YH0 ALA R 24  ? UNP P03435     ? ? linker                  -1  8   
1 8YH0 MET R 25  ? UNP P03435     ? ? linker                  0   9   
1 8YH0 GLY R 26  ? UNP P03435     ? ? linker                  1   10  
2 8YH0 GLY R 343 ? UNP W5QED6     ? ? linker                  318 11  
2 8YH0 SER R 344 ? UNP W5QED6     ? ? linker                  319 12  
2 8YH0 GLY R 345 ? UNP W5QED6     ? ? linker                  320 13  
2 8YH0 GLY R 346 ? UNP W5QED6     ? ? linker                  321 14  
2 8YH0 GLY R 347 ? UNP W5QED6     ? ? linker                  322 15  
2 8YH0 GLY R 348 ? UNP W5QED6     ? ? linker                  323 16  
2 8YH0 SER R 349 ? UNP W5QED6     ? ? linker                  324 17  
2 8YH0 GLY R 350 ? UNP W5QED6     ? ? linker                  325 18  
2 8YH0 GLY R 351 ? UNP W5QED6     ? ? linker                  326 19  
2 8YH0 SER R 352 ? UNP W5QED6     ? ? linker                  327 20  
2 8YH0 SER R 353 ? UNP W5QED6     ? ? linker                  328 21  
2 8YH0 SER R 354 ? UNP W5QED6     ? ? linker                  329 22  
2 8YH0 GLY R 355 ? UNP W5QED6     ? ? linker                  330 23  
2 8YH0 GLY R 356 ? UNP W5QED6     ? ? linker                  331 24  
2 8YH0 GLY R 515 ? UNP W5QED6     ? ? linker                  490 25  
2 8YH0 GLY R 516 ? UNP W5QED6     ? ? linker                  491 26  
2 8YH0 SER R 517 ? UNP W5QED6     ? ? linker                  492 27  
2 8YH0 GLY R 518 ? UNP W5QED6     ? ? linker                  493 28  
2 8YH0 GLY R 519 ? UNP W5QED6     ? ? linker                  494 29  
2 8YH0 GLY R 520 ? UNP W5QED6     ? ? linker                  495 30  
2 8YH0 GLY R 521 ? UNP W5QED6     ? ? linker                  496 31  
2 8YH0 SER R 522 ? UNP W5QED6     ? ? linker                  497 32  
2 8YH0 GLY R 523 ? UNP W5QED6     ? ? linker                  498 33  
2 8YH0 GLY R 524 ? UNP W5QED6     ? ? linker                  499 34  
2 8YH0 SER R 525 ? UNP W5QED6     ? ? linker                  500 35  
2 8YH0 SER R 526 ? UNP W5QED6     ? ? linker                  501 36  
2 8YH0 SER R 527 ? UNP W5QED6     ? ? linker                  502 37  
2 8YH0 GLY R 528 ? UNP W5QED6     ? ? linker                  503 38  
2 8YH0 GLY R 529 ? UNP W5QED6     ? ? linker                  504 39  
2 8YH0 LEU R 530 ? UNP W5QED6     ? ? linker                  505 40  
2 8YH0 GLU R 531 ? UNP W5QED6     ? ? linker                  506 41  
2 8YH0 VAL R 532 ? UNP W5QED6     ? ? linker                  507 42  
2 8YH0 LEU R 533 ? UNP W5QED6     ? ? linker                  508 43  
2 8YH0 PHE R 534 ? UNP W5QED6     ? ? linker                  509 44  
2 8YH0 GLN R 535 ? UNP W5QED6     ? ? linker                  510 45  
2 8YH0 GLY R 536 ? UNP W5QED6     ? ? linker                  511 46  
2 8YH0 PRO R 537 ? UNP W5QED6     ? ? linker                  512 47  
2 8YH0 GLY R 538 ? UNP W5QED6     ? ? linker                  513 48  
2 8YH0 SER R 539 ? UNP W5QED6     ? ? linker                  514 49  
2 8YH0 ALA R 540 ? UNP W5QED6     ? ? linker                  515 50  
2 8YH0 ALA R 541 ? UNP W5QED6     ? ? linker                  516 51  
2 8YH0 ALA R 542 ? UNP W5QED6     ? ? linker                  517 52  
2 8YH0 ALA R 543 ? UNP W5QED6     ? ? linker                  518 53  
4 8YH0 SER R 782 ? UNP A0A5P9VSM6 ? ? 'expression tag'        757 54  
4 8YH0 GLY R 783 ? UNP A0A5P9VSM6 ? ? 'expression tag'        758 55  
4 8YH0 LEU R 784 ? UNP A0A5P9VSM6 ? ? 'expression tag'        759 56  
4 8YH0 ARG R 785 ? UNP A0A5P9VSM6 ? ? 'expression tag'        760 57  
4 8YH0 SER R 786 ? UNP A0A5P9VSM6 ? ? 'expression tag'        761 58  
4 8YH0 HIS R 787 ? UNP A0A5P9VSM6 ? ? 'expression tag'        762 59  
4 8YH0 HIS R 788 ? UNP A0A5P9VSM6 ? ? 'expression tag'        763 60  
4 8YH0 HIS R 789 ? UNP A0A5P9VSM6 ? ? 'expression tag'        764 61  
4 8YH0 HIS R 790 ? UNP A0A5P9VSM6 ? ? 'expression tag'        765 62  
4 8YH0 HIS R 791 ? UNP A0A5P9VSM6 ? ? 'expression tag'        766 63  
4 8YH0 HIS R 792 ? UNP A0A5P9VSM6 ? ? 'expression tag'        767 64  
4 8YH0 HIS R 793 ? UNP A0A5P9VSM6 ? ? 'expression tag'        768 65  
4 8YH0 HIS R 794 ? UNP A0A5P9VSM6 ? ? 'expression tag'        769 66  
5 8YH0 GLY A 72  ? UNP P59768     ? ? linker                  -7  67  
5 8YH0 SER A 73  ? UNP P59768     ? ? linker                  -6  68  
5 8YH0 ALA A 74  ? UNP P59768     ? ? linker                  -5  69  
5 8YH0 GLY A 75  ? UNP P59768     ? ? linker                  -4  70  
5 8YH0 SER A 76  ? UNP P59768     ? ? linker                  -3  71  
5 8YH0 ALA A 77  ? UNP P59768     ? ? linker                  -2  72  
5 8YH0 GLY A 78  ? UNP P59768     ? ? linker                  -1  73  
5 8YH0 SER A 79  ? UNP P59768     ? ? linker                  0   74  
5 8YH0 ALA A 80  ? UNP P59768     ? ? linker                  1   75  
5 8YH0 MET A 81  ? UNP P59768     ? ? linker                  2   76  
7 8YH0 MET B 1   ? UNP P62871     ? ? 'initiating methionine' -4  77  
7 8YH0 GLY B 2   ? UNP P62871     ? ? 'expression tag'        -3  78  
7 8YH0 SER B 3   ? UNP P62871     ? ? 'expression tag'        -2  79  
7 8YH0 LEU B 4   ? UNP P62871     ? ? 'expression tag'        -1  80  
7 8YH0 LEU B 5   ? UNP P62871     ? ? 'expression tag'        0   81  
7 8YH0 GLN B 6   ? UNP P62871     ? ? 'expression tag'        1   82  
7 8YH0 GLY B 346 ? UNP P62871     ? ? 'expression tag'        341 83  
7 8YH0 ALA B 347 ? UNP P62871     ? ? 'expression tag'        342 84  
7 8YH0 SER B 348 ? UNP P62871     ? ? 'expression tag'        343 85  
7 8YH0 GLY B 349 ? UNP P62871     ? ? 'expression tag'        344 86  
7 8YH0 GLY B 350 ? UNP P62871     ? ? 'expression tag'        345 87  
7 8YH0 GLY B 351 ? UNP P62871     ? ? 'expression tag'        346 88  
7 8YH0 SER B 352 ? UNP P62871     ? ? 'expression tag'        347 89  
7 8YH0 GLY B 353 ? UNP P62871     ? ? 'expression tag'        348 90  
7 8YH0 GLY B 354 ? UNP P62871     ? ? 'expression tag'        349 91  
7 8YH0 ASN B 355 ? UNP P62871     ? ? 'expression tag'        350 92  
7 8YH0 SER B 356 ? UNP P62871     ? ? 'expression tag'        351 93  
7 8YH0 GLY B 357 ? UNP P62871     ? ? 'expression tag'        352 94  
7 8YH0 SER B 358 ? UNP P62871     ? ? 'expression tag'        353 95  
7 8YH0 SER B 359 ? UNP P62871     ? ? 'expression tag'        354 96  
7 8YH0 GLY B 360 ? UNP P62871     ? ? 'expression tag'        355 97  
7 8YH0 GLY B 361 ? UNP P62871     ? ? 'expression tag'        356 98  
7 8YH0 SER B 362 ? UNP P62871     ? ? 'expression tag'        357 99  
7 8YH0 SER B 363 ? UNP P62871     ? ? 'expression tag'        358 100 
7 8YH0 GLY B 364 ? UNP P62871     ? ? 'expression tag'        359 101 
7 8YH0 VAL B 365 ? UNP P62871     ? ? 'expression tag'        360 102 
7 8YH0 SER B 366 ? UNP P62871     ? ? 'expression tag'        361 103 
7 8YH0 GLY B 367 ? UNP P62871     ? ? 'expression tag'        362 104 
7 8YH0 TRP B 368 ? UNP P62871     ? ? 'expression tag'        363 105 
7 8YH0 ARG B 369 ? UNP P62871     ? ? 'expression tag'        364 106 
7 8YH0 LEU B 370 ? UNP P62871     ? ? 'expression tag'        365 107 
7 8YH0 PHE B 371 ? UNP P62871     ? ? 'expression tag'        366 108 
7 8YH0 LYS B 372 ? UNP P62871     ? ? 'expression tag'        367 109 
7 8YH0 LYS B 373 ? UNP P62871     ? ? 'expression tag'        368 110 
7 8YH0 ILE B 374 ? UNP P62871     ? ? 'expression tag'        369 111 
7 8YH0 SER B 375 ? UNP P62871     ? ? 'expression tag'        370 112 
8 8YH0 GLY G 72  ? UNP P59768     ? ? linker                  72  113 
8 8YH0 SER G 73  ? UNP P59768     ? ? linker                  73  114 
8 8YH0 ALA G 74  ? UNP P59768     ? ? linker                  74  115 
8 8YH0 GLY G 75  ? UNP P59768     ? ? linker                  75  116 
8 8YH0 SER G 76  ? UNP P59768     ? ? linker                  76  117 
8 8YH0 ALA G 77  ? UNP P59768     ? ? linker                  77  118 
8 8YH0 GLY G 78  ? UNP P59768     ? ? linker                  78  119 
8 8YH0 SER G 79  ? UNP P59768     ? ? linker                  79  120 
8 8YH0 ALA G 80  ? UNP P59768     ? ? linker                  80  121 
8 8YH0 MET G 81  ? UNP P59768     ? ? linker                  81  122 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 34  ? ASN A 65  ? SER R 9   ASN R 40  1 ? 32 
HELX_P HELX_P2  AA2 PRO A 66  ? GLN A 69  ? PRO R 41  GLN R 44  5 ? 4  
HELX_P HELX_P3  AA3 THR A 70  ? LEU A 89  ? THR R 45  LEU R 64  1 ? 20 
HELX_P HELX_P4  AA4 LEU A 89  ? GLY A 100 ? LEU R 64  GLY R 75  1 ? 12 
HELX_P HELX_P5  AA5 HIS A 104 ? THR A 140 ? HIS R 79  THR R 115 1 ? 37 
HELX_P HELX_P6  AA6 ARG A 142 ? THR A 147 ? ARG R 117 THR R 122 1 ? 6  
HELX_P HELX_P7  AA7 THR A 148 ? THR A 169 ? THR R 123 THR R 144 1 ? 22 
HELX_P HELX_P8  AA8 PRO A 170 ? GLY A 173 ? PRO R 145 GLY R 148 5 ? 4  
HELX_P HELX_P9  AA9 ASN A 175 ? SER A 179 ? ASN R 150 SER R 154 5 ? 5  
HELX_P HELX_P10 AB1 ARG A 191 ? MET A 196 ? ARG R 166 MET R 171 1 ? 6  
HELX_P HELX_P11 AB2 ARG A 197 ? PHE A 204 ? ARG R 172 PHE R 179 1 ? 8  
HELX_P HELX_P12 AB3 PHE A 204 ? ILE A 210 ? PHE R 179 ILE R 185 1 ? 7  
HELX_P HELX_P13 AB4 ILE A 210 ? LEU A 232 ? ILE R 185 LEU R 207 1 ? 23 
HELX_P HELX_P14 AB5 PHE A 250 ? PHE A 279 ? PHE R 225 PHE R 254 1 ? 30 
HELX_P HELX_P15 AB6 PRO A 284 ? ALA A 307 ? PRO R 259 ALA R 282 1 ? 24 
HELX_P HELX_P16 AB7 ILE A 310 ? ILE A 320 ? ILE R 285 ILE R 295 1 ? 11 
HELX_P HELX_P17 AB8 SER B 85  ? ARG B 111 ? SER A 6   ARG A 32  1 ? 27 
HELX_P HELX_P18 AB9 GLY B 124 ? MET B 132 ? GLY A 45  MET A 53  1 ? 9  
HELX_P HELX_P19 AC1 TRP B 290 ? GLU B 295 ? TRP A 211 GLU A 216 5 ? 6  
HELX_P HELX_P20 AC2 ARG B 321 ? ASN B 335 ? ARG A 242 ASN A 256 1 ? 15 
HELX_P HELX_P21 AC3 THR B 374 ? LEU B 389 ? THR A 295 LEU A 310 1 ? 16 
HELX_P HELX_P22 AC4 LYS B 409 ? LYS B 428 ? LYS A 330 LYS A 349 1 ? 20 
HELX_P HELX_P23 AC5 GLN C 11  ? ALA C 31  ? GLN B 6   ALA B 26  1 ? 21 
HELX_P HELX_P24 AC6 THR C 34  ? THR C 39  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P25 AC7 ALA D 10  ? ASN D 24  ? ALA G 10  ASN G 24  1 ? 15 
HELX_P HELX_P26 AC8 LYS D 29  ? HIS D 44  ? LYS G 29  HIS G 44  1 ? 16 
HELX_P HELX_P27 AC9 ALA E 28  ? PHE E 32  ? ALA S 28  PHE S 32  5 ? 5  
HELX_P HELX_P28 AD1 ARG E 87  ? THR E 91  ? ARG S 87  THR S 91  5 ? 5  
HELX_P HELX_P29 AD2 GLU E 220 ? VAL E 224 ? GLU S 208 VAL S 212 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 108 SG ? ? ? 1_555 A CYS 190 SG ? ? R CYS 83  R CYS 165 1_555 ? ? ? ? ? ? ? 2.026 ? ? 
disulf2 disulf ? ? E CYS 22  SG ? ? ? 1_555 E CYS 96  SG ? ? S CYS 22  S CYS 96  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf3 disulf ? ? E CYS 159 SG ? ? ? 1_555 E CYS 229 SG ? ? S CYS 147 S CYS 217 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 108 ? CYS A 190 ? CYS R 83  ? 1_555 CYS R 165 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS E 22  ? CYS E 96  ? CYS S 22  ? 1_555 CYS S 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 159 ? CYS E 229 ? CYS S 147 ? 1_555 CYS S 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           235 
_struct_mon_prot_cis.label_asym_id          E 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            223 
_struct_mon_prot_cis.auth_asym_id           S 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    236 
_struct_mon_prot_cis.pdbx_label_asym_id_2   E 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     224 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    S 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       1.74 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL B 264 ? PHE B 270 ? VAL A 185 PHE A 191 
AA1 2 LEU B 273 ? ASP B 279 ? LEU A 194 ASP A 200 
AA1 3 VAL B 113 ? GLY B 119 ? VAL A 34  GLY A 40  
AA1 4 ALA B 299 ? CYS B 303 ? ALA A 220 CYS A 224 
AA1 5 SER B 342 ? PHE B 346 ? SER A 263 PHE A 267 
AA1 6 ILE B 398 ? HIS B 401 ? ILE A 319 HIS A 322 
AA2 1 THR C 52  ? LEU C 56  ? THR B 47  LEU B 51  
AA2 2 LEU C 341 ? TRP C 344 ? LEU B 336 TRP B 339 
AA2 3 VAL C 332 ? SER C 336 ? VAL B 327 SER B 331 
AA2 4 VAL C 320 ? VAL C 325 ? VAL B 315 VAL B 320 
AA3 1 ILE C 63  ? TRP C 68  ? ILE B 58  TRP B 63  
AA3 2 LEU C 74  ? SER C 79  ? LEU B 69  SER B 74  
AA3 3 LYS C 83  ? ASP C 88  ? LYS B 78  ASP B 83  
AA3 4 ASN C 93  ? PRO C 99  ? ASN B 88  PRO B 94  
AA4 1 VAL C 105 ? TYR C 110 ? VAL B 100 TYR B 105 
AA4 2 TYR C 116 ? GLY C 121 ? TYR B 111 GLY B 116 
AA4 3 ILE C 125 ? ASN C 130 ? ILE B 120 ASN B 125 
AA4 4 ARG C 139 ? ALA C 145 ? ARG B 134 ALA B 140 
AA5 1 LEU C 151 ? ASP C 158 ? LEU B 146 ASP B 153 
AA5 2 GLN C 161 ? SER C 166 ? GLN B 156 SER B 161 
AA5 3 THR C 170 ? ASP C 175 ? THR B 165 ASP B 170 
AA5 4 GLN C 181 ? THR C 186 ? GLN B 176 THR B 181 
AA6 1 VAL C 192 ? LEU C 197 ? VAL B 187 LEU B 192 
AA6 2 LEU C 203 ? ALA C 208 ? LEU B 198 ALA B 203 
AA6 3 ALA C 213 ? ASP C 217 ? ALA B 208 ASP B 212 
AA6 4 CYS C 223 ? PHE C 227 ? CYS B 218 PHE B 222 
AA7 1 ILE C 234 ? PHE C 239 ? ILE B 229 PHE B 234 
AA7 2 ALA C 245 ? SER C 250 ? ALA B 240 SER B 245 
AA7 3 CYS C 255 ? ASP C 259 ? CYS B 250 ASP B 254 
AA7 4 GLU C 265 ? TYR C 269 ? GLU B 260 TYR B 264 
AA8 1 ILE C 278 ? PHE C 283 ? ILE B 273 PHE B 278 
AA8 2 LEU C 289 ? TYR C 294 ? LEU B 284 TYR B 289 
AA8 3 CYS C 299 ? ASP C 303 ? CYS B 294 ASP B 298 
AA8 4 ARG C 309 ? VAL C 312 ? ARG B 304 VAL B 307 
AA9 1 GLN E 3   ? SER E 7   ? GLN S 3   SER S 7   
AA9 2 ARG E 18  ? SER E 25  ? ARG S 18  SER S 25  
AA9 3 THR E 78  ? MET E 83  ? THR S 78  MET S 83  
AA9 4 THR E 69  ? ASP E 73  ? THR S 69  ASP S 73  
AB1 1 GLY E 10  ? VAL E 12  ? GLY S 10  VAL S 12  
AB1 2 THR E 115 ? VAL E 119 ? THR S 115 VAL S 119 
AB1 3 ALA E 92  ? SER E 99  ? ALA S 92  SER S 99  
AB1 4 GLY E 33  ? ALA E 40  ? GLY S 33  ALA S 40  
AB1 5 GLY E 44  ? ILE E 51  ? GLY S 44  ILE S 51  
AB1 6 ILE E 58  ? TYR E 60  ? ILE S 58  TYR S 60  
AB2 1 MET E 140 ? GLN E 142 ? MET S 128 GLN S 130 
AB2 2 VAL E 155 ? SER E 161 ? VAL S 143 SER S 149 
AB2 3 ALA E 211 ? ILE E 216 ? ALA S 199 ILE S 204 
AB2 4 PHE E 203 ? SER E 208 ? PHE S 191 SER S 196 
AB3 1 SER E 146 ? PRO E 148 ? SER S 134 PRO S 136 
AB3 2 THR E 243 ? GLU E 246 ? THR S 231 GLU S 234 
AB3 3 VAL E 226 ? TYR E 228 ? VAL S 214 TYR S 216 
AB3 4 TRP E 176 ? GLN E 179 ? TRP S 164 GLN S 167 
AB3 5 PRO E 185 ? ILE E 189 ? PRO S 173 ILE S 177 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE B 268 ? N PHE A 189 O PHE B 275 ? O PHE A 196 
AA1 2 3 O LYS B 276 ? O LYS A 197 N LEU B 115 ? N LEU A 36  
AA1 3 4 N LEU B 116 ? N LEU A 37  O ILE B 301 ? O ILE A 222 
AA1 4 5 N ILE B 300 ? N ILE A 221 O ILE B 344 ? O ILE A 265 
AA1 5 6 N ILE B 343 ? N ILE A 264 O TYR B 399 ? O TYR A 320 
AA2 1 2 N ARG C 54  ? N ARG B 49  O ILE C 343 ? O ILE B 338 
AA2 2 3 O TRP C 344 ? O TRP B 339 N VAL C 332 ? N VAL B 327 
AA2 3 4 O GLY C 335 ? O GLY B 330 N CYS C 322 ? N CYS B 317 
AA3 1 2 N HIS C 67  ? N HIS B 62  O VAL C 76  ? O VAL B 71  
AA3 2 3 N SER C 77  ? N SER B 72  O ILE C 85  ? O ILE B 80  
AA3 3 4 N ASP C 88  ? N ASP B 83  O ASN C 93  ? O ASN B 88  
AA4 1 2 N MET C 106 ? N MET B 101 O GLY C 120 ? O GLY B 115 
AA4 2 3 N VAL C 117 ? N VAL B 112 O TYR C 129 ? O TYR B 124 
AA4 3 4 N ILE C 128 ? N ILE B 123 O ARG C 142 ? O ARG B 137 
AA5 1 2 N LEU C 157 ? N LEU B 152 O GLN C 161 ? O GLN B 156 
AA5 2 3 N ILE C 162 ? N ILE B 157 O TRP C 174 ? O TRP B 169 
AA5 3 4 N CYS C 171 ? N CYS B 166 O PHE C 185 ? O PHE B 180 
AA6 1 2 N MET C 193 ? N MET B 188 O GLY C 207 ? O GLY B 202 
AA6 2 3 N SER C 206 ? N SER B 201 O LYS C 214 ? O LYS B 209 
AA6 3 4 N ALA C 213 ? N ALA B 208 O PHE C 227 ? O PHE B 222 
AA7 1 2 N ALA C 236 ? N ALA B 231 O GLY C 249 ? O GLY B 244 
AA7 2 3 N PHE C 246 ? N PHE B 241 O PHE C 258 ? O PHE B 253 
AA7 3 4 N CYS C 255 ? N CYS B 250 O TYR C 269 ? O TYR B 264 
AA8 1 2 N THR C 279 ? N THR B 274 O GLY C 293 ? O GLY B 288 
AA8 2 3 N LEU C 290 ? N LEU B 285 O TRP C 302 ? O TRP B 297 
AA8 3 4 N VAL C 301 ? N VAL B 296 O ALA C 310 ? O ALA B 305 
AA9 1 2 N VAL E 5   ? N VAL S 5   O SER E 23  ? O SER S 23  
AA9 2 3 N LEU E 20  ? N LEU S 20  O LEU E 81  ? O LEU S 81  
AA9 3 4 O PHE E 80  ? O PHE S 80  N SER E 71  ? N SER S 71  
AB1 1 2 N GLY E 10  ? N GLY S 10  O THR E 118 ? O THR S 118 
AB1 2 3 O THR E 115 ? O THR S 115 N TYR E 94  ? N TYR S 94  
AB1 3 4 O MET E 93  ? O MET S 93  N GLN E 39  ? N GLN S 39  
AB1 4 5 N ARG E 38  ? N ARG S 38  O GLU E 46  ? O GLU S 46  
AB1 5 6 N TYR E 50  ? N TYR S 50  O TYR E 59  ? O TYR S 59  
AB2 1 2 N THR E 141 ? N THR S 129 O ARG E 160 ? O ARG S 148 
AB2 2 3 N VAL E 155 ? N VAL S 143 O ILE E 216 ? O ILE S 204 
AB2 3 4 O THR E 213 ? O THR S 201 N SER E 206 ? N SER S 194 
AB3 1 2 N VAL E 147 ? N VAL S 135 O GLU E 246 ? O GLU S 234 
AB3 2 3 O THR E 243 ? O THR S 231 N TYR E 227 ? N TYR S 215 
AB3 3 4 O VAL E 226 ? O VAL S 214 N GLN E 179 ? N GLN S 167 
AB3 4 5 N TRP E 176 ? N TRP S 164 O LEU E 188 ? O LEU S 176 
# 
_pdbx_entry_details.entry_id                   8YH0 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   B ILE 58  ? ? OG  B SER 316 ? ? 2.10 
2 1 OE1 A GLU 14  ? ? OG1 S THR 57  ? ? 2.10 
3 1 OE1 S GLN 130 ? ? OG1 S THR 231 ? ? 2.12 
4 1 OH  B TYR 264 ? ? O   B ALA 299 ? ? 2.13 
5 1 OH  A TYR 287 ? ? OE1 A GLN 306 ? ? 2.19 
6 1 OG  S SER 99  ? ? O   S PRO 107 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 HIS R 79  ? ? 71.01   151.67  
2  1 THR R 115 ? ? 64.31   -121.14 
3  1 PHE R 147 ? ? -99.21  30.52   
4  1 LYS A 349 ? ? -69.22  0.57    
5  1 LEU A 353 ? ? -76.91  31.29   
6  1 PHE S 68  ? ? 118.14  160.17  
7  1 THR S 84  ? ? -90.88  -60.47  
8  1 PHE S 108 ? ? -142.00 45.08   
9  1 ARG S 179 ? ? -128.81 -63.93  
10 1 SER S 181 ? ? 68.15   -3.22   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8YH0 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8YH0 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.86 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               210192 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'A3R-Gi complex bound to NECA' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2,3,4 
# 
_em_imaging.entry_id                        8YH0 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8YH0 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8YH0 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1    1 Y 1 R MET -24 ? A MET 1   
2    1 Y 1 R LYS -23 ? A LYS 2   
3    1 Y 1 R THR -22 ? A THR 3   
4    1 Y 1 R ILE -21 ? A ILE 4   
5    1 Y 1 R ILE -20 ? A ILE 5   
6    1 Y 1 R ALA -19 ? A ALA 6   
7    1 Y 1 R LEU -18 ? A LEU 7   
8    1 Y 1 R SER -17 ? A SER 8   
9    1 Y 1 R TYR -16 ? A TYR 9   
10   1 Y 1 R ILE -15 ? A ILE 10  
11   1 Y 1 R PHE -14 ? A PHE 11  
12   1 Y 1 R CYS -13 ? A CYS 12  
13   1 Y 1 R LEU -12 ? A LEU 13  
14   1 Y 1 R VAL -11 ? A VAL 14  
15   1 Y 1 R PHE -10 ? A PHE 15  
16   1 Y 1 R ALA -9  ? A ALA 16  
17   1 Y 1 R ASP -8  ? A ASP 17  
18   1 Y 1 R TYR -7  ? A TYR 18  
19   1 Y 1 R LYS -6  ? A LYS 19  
20   1 Y 1 R ASP -5  ? A ASP 20  
21   1 Y 1 R ASP -4  ? A ASP 21  
22   1 Y 1 R ASP -3  ? A ASP 22  
23   1 Y 1 R ASP -2  ? A ASP 23  
24   1 Y 1 R ALA -1  ? A ALA 24  
25   1 Y 1 R MET 0   ? A MET 25  
26   1 Y 1 R GLY 1   ? A GLY 26  
27   1 Y 1 R PRO 2   ? A PRO 27  
28   1 Y 1 R VAL 3   ? A VAL 28  
29   1 Y 1 R ASN 4   ? A ASN 29  
30   1 Y 1 R SER 5   ? A SER 30  
31   1 Y 1 R THR 6   ? A THR 31  
32   1 Y 1 R ALA 7   ? A ALA 32  
33   1 Y 1 R VAL 8   ? A VAL 33  
34   1 Y 1 R SER 208 ? A SER 233 
35   1 Y 1 R GLN 209 ? A GLN 234 
36   1 Y 1 R SER 210 ? A SER 235 
37   1 Y 1 R PHE 211 ? A PHE 236 
38   1 Y 1 R SER 212 ? A SER 237 
39   1 Y 1 R GLY 213 ? A GLY 238 
40   1 Y 1 R SER 214 ? A SER 239 
41   1 Y 1 R ARG 215 ? A ARG 240 
42   1 Y 1 R GLU 216 ? A GLU 241 
43   1 Y 1 R THR 217 ? A THR 242 
44   1 Y 1 R GLY 218 ? A GLY 243 
45   1 Y 1 R ALA 219 ? A ALA 244 
46   1 Y 1 R PHE 220 ? A PHE 245 
47   1 Y 1 R TYR 221 ? A TYR 246 
48   1 Y 1 R GLY 222 ? A GLY 247 
49   1 Y 1 R ARG 223 ? A ARG 248 
50   1 Y 1 R LEU 296 ? A LEU 321 
51   1 Y 1 R LYS 297 ? A LYS 322 
52   1 Y 1 R ALA 298 ? A ALA 323 
53   1 Y 1 R CYS 299 ? A CYS 324 
54   1 Y 1 R VAL 300 ? A VAL 325 
55   1 Y 1 R ILE 301 ? A ILE 326 
56   1 Y 1 R CYS 302 ? A CYS 327 
57   1 Y 1 R GLN 303 ? A GLN 328 
58   1 Y 1 R PRO 304 ? A PRO 329 
59   1 Y 1 R SER 305 ? A SER 330 
60   1 Y 1 R LYS 306 ? A LYS 331 
61   1 Y 1 R SER 307 ? A SER 332 
62   1 Y 1 R MET 308 ? A MET 333 
63   1 Y 1 R ASP 309 ? A ASP 334 
64   1 Y 1 R PRO 310 ? A PRO 335 
65   1 Y 1 R SER 311 ? A SER 336 
66   1 Y 1 R THR 312 ? A THR 337 
67   1 Y 1 R GLU 313 ? A GLU 338 
68   1 Y 1 R GLN 314 ? A GLN 339 
69   1 Y 1 R THR 315 ? A THR 340 
70   1 Y 1 R SER 316 ? A SER 341 
71   1 Y 1 R GLU 317 ? A GLU 342 
72   1 Y 1 R GLY 318 ? A GLY 343 
73   1 Y 1 R SER 319 ? A SER 344 
74   1 Y 1 R GLY 320 ? A GLY 345 
75   1 Y 1 R GLY 321 ? A GLY 346 
76   1 Y 1 R GLY 322 ? A GLY 347 
77   1 Y 1 R GLY 323 ? A GLY 348 
78   1 Y 1 R SER 324 ? A SER 349 
79   1 Y 1 R GLY 325 ? A GLY 350 
80   1 Y 1 R GLY 326 ? A GLY 351 
81   1 Y 1 R SER 327 ? A SER 352 
82   1 Y 1 R SER 328 ? A SER 353 
83   1 Y 1 R SER 329 ? A SER 354 
84   1 Y 1 R GLY 330 ? A GLY 355 
85   1 Y 1 R GLY 331 ? A GLY 356 
86   1 Y 1 R VAL 332 ? A VAL 357 
87   1 Y 1 R PHE 333 ? A PHE 358 
88   1 Y 1 R THR 334 ? A THR 359 
89   1 Y 1 R LEU 335 ? A LEU 360 
90   1 Y 1 R GLU 336 ? A GLU 361 
91   1 Y 1 R ASP 337 ? A ASP 362 
92   1 Y 1 R PHE 338 ? A PHE 363 
93   1 Y 1 R VAL 339 ? A VAL 364 
94   1 Y 1 R GLY 340 ? A GLY 365 
95   1 Y 1 R ASP 341 ? A ASP 366 
96   1 Y 1 R TRP 342 ? A TRP 367 
97   1 Y 1 R GLU 343 ? A GLU 368 
98   1 Y 1 R GLN 344 ? A GLN 369 
99   1 Y 1 R THR 345 ? A THR 370 
100  1 Y 1 R ALA 346 ? A ALA 371 
101  1 Y 1 R ALA 347 ? A ALA 372 
102  1 Y 1 R TYR 348 ? A TYR 373 
103  1 Y 1 R ASN 349 ? A ASN 374 
104  1 Y 1 R LEU 350 ? A LEU 375 
105  1 Y 1 R ASP 351 ? A ASP 376 
106  1 Y 1 R GLN 352 ? A GLN 377 
107  1 Y 1 R VAL 353 ? A VAL 378 
108  1 Y 1 R LEU 354 ? A LEU 379 
109  1 Y 1 R GLU 355 ? A GLU 380 
110  1 Y 1 R GLN 356 ? A GLN 381 
111  1 Y 1 R GLY 357 ? A GLY 382 
112  1 Y 1 R GLY 358 ? A GLY 383 
113  1 Y 1 R VAL 359 ? A VAL 384 
114  1 Y 1 R SER 360 ? A SER 385 
115  1 Y 1 R SER 361 ? A SER 386 
116  1 Y 1 R LEU 362 ? A LEU 387 
117  1 Y 1 R LEU 363 ? A LEU 388 
118  1 Y 1 R GLN 364 ? A GLN 389 
119  1 Y 1 R ASN 365 ? A ASN 390 
120  1 Y 1 R LEU 366 ? A LEU 391 
121  1 Y 1 R ALA 367 ? A ALA 392 
122  1 Y 1 R VAL 368 ? A VAL 393 
123  1 Y 1 R SER 369 ? A SER 394 
124  1 Y 1 R VAL 370 ? A VAL 395 
125  1 Y 1 R THR 371 ? A THR 396 
126  1 Y 1 R PRO 372 ? A PRO 397 
127  1 Y 1 R ILE 373 ? A ILE 398 
128  1 Y 1 R GLN 374 ? A GLN 399 
129  1 Y 1 R ARG 375 ? A ARG 400 
130  1 Y 1 R ILE 376 ? A ILE 401 
131  1 Y 1 R VAL 377 ? A VAL 402 
132  1 Y 1 R ARG 378 ? A ARG 403 
133  1 Y 1 R SER 379 ? A SER 404 
134  1 Y 1 R GLY 380 ? A GLY 405 
135  1 Y 1 R GLU 381 ? A GLU 406 
136  1 Y 1 R ASN 382 ? A ASN 407 
137  1 Y 1 R ALA 383 ? A ALA 408 
138  1 Y 1 R LEU 384 ? A LEU 409 
139  1 Y 1 R LYS 385 ? A LYS 410 
140  1 Y 1 R ILE 386 ? A ILE 411 
141  1 Y 1 R ASP 387 ? A ASP 412 
142  1 Y 1 R ILE 388 ? A ILE 413 
143  1 Y 1 R HIS 389 ? A HIS 414 
144  1 Y 1 R VAL 390 ? A VAL 415 
145  1 Y 1 R ILE 391 ? A ILE 416 
146  1 Y 1 R ILE 392 ? A ILE 417 
147  1 Y 1 R PRO 393 ? A PRO 418 
148  1 Y 1 R TYR 394 ? A TYR 419 
149  1 Y 1 R GLU 395 ? A GLU 420 
150  1 Y 1 R GLY 396 ? A GLY 421 
151  1 Y 1 R LEU 397 ? A LEU 422 
152  1 Y 1 R SER 398 ? A SER 423 
153  1 Y 1 R ALA 399 ? A ALA 424 
154  1 Y 1 R ASP 400 ? A ASP 425 
155  1 Y 1 R GLN 401 ? A GLN 426 
156  1 Y 1 R MET 402 ? A MET 427 
157  1 Y 1 R ALA 403 ? A ALA 428 
158  1 Y 1 R GLN 404 ? A GLN 429 
159  1 Y 1 R ILE 405 ? A ILE 430 
160  1 Y 1 R GLU 406 ? A GLU 431 
161  1 Y 1 R GLU 407 ? A GLU 432 
162  1 Y 1 R VAL 408 ? A VAL 433 
163  1 Y 1 R PHE 409 ? A PHE 434 
164  1 Y 1 R LYS 410 ? A LYS 435 
165  1 Y 1 R VAL 411 ? A VAL 436 
166  1 Y 1 R VAL 412 ? A VAL 437 
167  1 Y 1 R TYR 413 ? A TYR 438 
168  1 Y 1 R PRO 414 ? A PRO 439 
169  1 Y 1 R VAL 415 ? A VAL 440 
170  1 Y 1 R ASP 416 ? A ASP 441 
171  1 Y 1 R ASP 417 ? A ASP 442 
172  1 Y 1 R HIS 418 ? A HIS 443 
173  1 Y 1 R HIS 419 ? A HIS 444 
174  1 Y 1 R PHE 420 ? A PHE 445 
175  1 Y 1 R LYS 421 ? A LYS 446 
176  1 Y 1 R VAL 422 ? A VAL 447 
177  1 Y 1 R ILE 423 ? A ILE 448 
178  1 Y 1 R LEU 424 ? A LEU 449 
179  1 Y 1 R PRO 425 ? A PRO 450 
180  1 Y 1 R TYR 426 ? A TYR 451 
181  1 Y 1 R GLY 427 ? A GLY 452 
182  1 Y 1 R THR 428 ? A THR 453 
183  1 Y 1 R LEU 429 ? A LEU 454 
184  1 Y 1 R VAL 430 ? A VAL 455 
185  1 Y 1 R ILE 431 ? A ILE 456 
186  1 Y 1 R ASP 432 ? A ASP 457 
187  1 Y 1 R GLY 433 ? A GLY 458 
188  1 Y 1 R VAL 434 ? A VAL 459 
189  1 Y 1 R THR 435 ? A THR 460 
190  1 Y 1 R PRO 436 ? A PRO 461 
191  1 Y 1 R ASN 437 ? A ASN 462 
192  1 Y 1 R MET 438 ? A MET 463 
193  1 Y 1 R LEU 439 ? A LEU 464 
194  1 Y 1 R ASN 440 ? A ASN 465 
195  1 Y 1 R TYR 441 ? A TYR 466 
196  1 Y 1 R PHE 442 ? A PHE 467 
197  1 Y 1 R GLY 443 ? A GLY 468 
198  1 Y 1 R ARG 444 ? A ARG 469 
199  1 Y 1 R PRO 445 ? A PRO 470 
200  1 Y 1 R TYR 446 ? A TYR 471 
201  1 Y 1 R GLU 447 ? A GLU 472 
202  1 Y 1 R GLY 448 ? A GLY 473 
203  1 Y 1 R ILE 449 ? A ILE 474 
204  1 Y 1 R ALA 450 ? A ALA 475 
205  1 Y 1 R VAL 451 ? A VAL 476 
206  1 Y 1 R PHE 452 ? A PHE 477 
207  1 Y 1 R ASP 453 ? A ASP 478 
208  1 Y 1 R GLY 454 ? A GLY 479 
209  1 Y 1 R LYS 455 ? A LYS 480 
210  1 Y 1 R LYS 456 ? A LYS 481 
211  1 Y 1 R ILE 457 ? A ILE 482 
212  1 Y 1 R THR 458 ? A THR 483 
213  1 Y 1 R VAL 459 ? A VAL 484 
214  1 Y 1 R THR 460 ? A THR 485 
215  1 Y 1 R GLY 461 ? A GLY 486 
216  1 Y 1 R THR 462 ? A THR 487 
217  1 Y 1 R LEU 463 ? A LEU 488 
218  1 Y 1 R TRP 464 ? A TRP 489 
219  1 Y 1 R ASN 465 ? A ASN 490 
220  1 Y 1 R GLY 466 ? A GLY 491 
221  1 Y 1 R ASN 467 ? A ASN 492 
222  1 Y 1 R LYS 468 ? A LYS 493 
223  1 Y 1 R ILE 469 ? A ILE 494 
224  1 Y 1 R ILE 470 ? A ILE 495 
225  1 Y 1 R ASP 471 ? A ASP 496 
226  1 Y 1 R GLU 472 ? A GLU 497 
227  1 Y 1 R ARG 473 ? A ARG 498 
228  1 Y 1 R LEU 474 ? A LEU 499 
229  1 Y 1 R ILE 475 ? A ILE 500 
230  1 Y 1 R THR 476 ? A THR 501 
231  1 Y 1 R PRO 477 ? A PRO 502 
232  1 Y 1 R ASP 478 ? A ASP 503 
233  1 Y 1 R GLY 479 ? A GLY 504 
234  1 Y 1 R SER 480 ? A SER 505 
235  1 Y 1 R MET 481 ? A MET 506 
236  1 Y 1 R LEU 482 ? A LEU 507 
237  1 Y 1 R PHE 483 ? A PHE 508 
238  1 Y 1 R ARG 484 ? A ARG 509 
239  1 Y 1 R VAL 485 ? A VAL 510 
240  1 Y 1 R THR 486 ? A THR 511 
241  1 Y 1 R ILE 487 ? A ILE 512 
242  1 Y 1 R ASN 488 ? A ASN 513 
243  1 Y 1 R SER 489 ? A SER 514 
244  1 Y 1 R GLY 490 ? A GLY 515 
245  1 Y 1 R GLY 491 ? A GLY 516 
246  1 Y 1 R SER 492 ? A SER 517 
247  1 Y 1 R GLY 493 ? A GLY 518 
248  1 Y 1 R GLY 494 ? A GLY 519 
249  1 Y 1 R GLY 495 ? A GLY 520 
250  1 Y 1 R GLY 496 ? A GLY 521 
251  1 Y 1 R SER 497 ? A SER 522 
252  1 Y 1 R GLY 498 ? A GLY 523 
253  1 Y 1 R GLY 499 ? A GLY 524 
254  1 Y 1 R SER 500 ? A SER 525 
255  1 Y 1 R SER 501 ? A SER 526 
256  1 Y 1 R SER 502 ? A SER 527 
257  1 Y 1 R GLY 503 ? A GLY 528 
258  1 Y 1 R GLY 504 ? A GLY 529 
259  1 Y 1 R LEU 505 ? A LEU 530 
260  1 Y 1 R GLU 506 ? A GLU 531 
261  1 Y 1 R VAL 507 ? A VAL 532 
262  1 Y 1 R LEU 508 ? A LEU 533 
263  1 Y 1 R PHE 509 ? A PHE 534 
264  1 Y 1 R GLN 510 ? A GLN 535 
265  1 Y 1 R GLY 511 ? A GLY 536 
266  1 Y 1 R PRO 512 ? A PRO 537 
267  1 Y 1 R GLY 513 ? A GLY 538 
268  1 Y 1 R SER 514 ? A SER 539 
269  1 Y 1 R ALA 515 ? A ALA 540 
270  1 Y 1 R ALA 516 ? A ALA 541 
271  1 Y 1 R ALA 517 ? A ALA 542 
272  1 Y 1 R ALA 518 ? A ALA 543 
273  1 Y 1 R VAL 519 ? A VAL 544 
274  1 Y 1 R SER 520 ? A SER 545 
275  1 Y 1 R LYS 521 ? A LYS 546 
276  1 Y 1 R GLY 522 ? A GLY 547 
277  1 Y 1 R GLU 523 ? A GLU 548 
278  1 Y 1 R GLU 524 ? A GLU 549 
279  1 Y 1 R LEU 525 ? A LEU 550 
280  1 Y 1 R PHE 526 ? A PHE 551 
281  1 Y 1 R THR 527 ? A THR 552 
282  1 Y 1 R GLY 528 ? A GLY 553 
283  1 Y 1 R VAL 529 ? A VAL 554 
284  1 Y 1 R VAL 530 ? A VAL 555 
285  1 Y 1 R PRO 531 ? A PRO 556 
286  1 Y 1 R ILE 532 ? A ILE 557 
287  1 Y 1 R LEU 533 ? A LEU 558 
288  1 Y 1 R VAL 534 ? A VAL 559 
289  1 Y 1 R GLU 535 ? A GLU 560 
290  1 Y 1 R LEU 536 ? A LEU 561 
291  1 Y 1 R ASP 537 ? A ASP 562 
292  1 Y 1 R GLY 538 ? A GLY 563 
293  1 Y 1 R ASP 539 ? A ASP 564 
294  1 Y 1 R VAL 540 ? A VAL 565 
295  1 Y 1 R ASN 541 ? A ASN 566 
296  1 Y 1 R GLY 542 ? A GLY 567 
297  1 Y 1 R HIS 543 ? A HIS 568 
298  1 Y 1 R LYS 544 ? A LYS 569 
299  1 Y 1 R PHE 545 ? A PHE 570 
300  1 Y 1 R SER 546 ? A SER 571 
301  1 Y 1 R VAL 547 ? A VAL 572 
302  1 Y 1 R SER 548 ? A SER 573 
303  1 Y 1 R GLY 549 ? A GLY 574 
304  1 Y 1 R GLU 550 ? A GLU 575 
305  1 Y 1 R GLY 551 ? A GLY 576 
306  1 Y 1 R GLU 552 ? A GLU 577 
307  1 Y 1 R GLY 553 ? A GLY 578 
308  1 Y 1 R ASP 554 ? A ASP 579 
309  1 Y 1 R ALA 555 ? A ALA 580 
310  1 Y 1 R THR 556 ? A THR 581 
311  1 Y 1 R TYR 557 ? A TYR 582 
312  1 Y 1 R GLY 558 ? A GLY 583 
313  1 Y 1 R LYS 559 ? A LYS 584 
314  1 Y 1 R LEU 560 ? A LEU 585 
315  1 Y 1 R THR 561 ? A THR 586 
316  1 Y 1 R LEU 562 ? A LEU 587 
317  1 Y 1 R LYS 563 ? A LYS 588 
318  1 Y 1 R PHE 564 ? A PHE 589 
319  1 Y 1 R ILE 565 ? A ILE 590 
320  1 Y 1 R CYS 566 ? A CYS 591 
321  1 Y 1 R THR 567 ? A THR 592 
322  1 Y 1 R THR 568 ? A THR 593 
323  1 Y 1 R GLY 569 ? A GLY 594 
324  1 Y 1 R LYS 570 ? A LYS 595 
325  1 Y 1 R LEU 571 ? A LEU 596 
326  1 Y 1 R PRO 572 ? A PRO 597 
327  1 Y 1 R VAL 573 ? A VAL 598 
328  1 Y 1 R PRO 574 ? A PRO 599 
329  1 Y 1 R TRP 575 ? A TRP 600 
330  1 Y 1 R PRO 576 ? A PRO 601 
331  1 Y 1 R THR 577 ? A THR 602 
332  1 Y 1 R LEU 578 ? A LEU 603 
333  1 Y 1 R VAL 579 ? A VAL 604 
334  1 Y 1 R THR 580 ? A THR 605 
335  1 Y 1 R THR 581 ? A THR 606 
336  1 Y 1 R LEU 582 ? A LEU 607 
337  1 Y 1 R THR 583 ? A THR 608 
338  1 Y 1 R TYR 584 ? A TYR 609 
339  1 Y 1 R GLY 585 ? A GLY 610 
340  1 Y 1 R VAL 586 ? A VAL 611 
341  1 Y 1 R GLN 587 ? A GLN 612 
342  1 Y 1 R CYS 588 ? A CYS 613 
343  1 Y 1 R PHE 589 ? A PHE 614 
344  1 Y 1 R SER 590 ? A SER 615 
345  1 Y 1 R ARG 591 ? A ARG 616 
346  1 Y 1 R TYR 592 ? A TYR 617 
347  1 Y 1 R PRO 593 ? A PRO 618 
348  1 Y 1 R ASP 594 ? A ASP 619 
349  1 Y 1 R HIS 595 ? A HIS 620 
350  1 Y 1 R MET 596 ? A MET 621 
351  1 Y 1 R LYS 597 ? A LYS 622 
352  1 Y 1 R GLN 598 ? A GLN 623 
353  1 Y 1 R HIS 599 ? A HIS 624 
354  1 Y 1 R ASP 600 ? A ASP 625 
355  1 Y 1 R PHE 601 ? A PHE 626 
356  1 Y 1 R PHE 602 ? A PHE 627 
357  1 Y 1 R LYS 603 ? A LYS 628 
358  1 Y 1 R SER 604 ? A SER 629 
359  1 Y 1 R ALA 605 ? A ALA 630 
360  1 Y 1 R MET 606 ? A MET 631 
361  1 Y 1 R PRO 607 ? A PRO 632 
362  1 Y 1 R GLU 608 ? A GLU 633 
363  1 Y 1 R GLY 609 ? A GLY 634 
364  1 Y 1 R TYR 610 ? A TYR 635 
365  1 Y 1 R VAL 611 ? A VAL 636 
366  1 Y 1 R GLN 612 ? A GLN 637 
367  1 Y 1 R GLU 613 ? A GLU 638 
368  1 Y 1 R ARG 614 ? A ARG 639 
369  1 Y 1 R THR 615 ? A THR 640 
370  1 Y 1 R ILE 616 ? A ILE 641 
371  1 Y 1 R PHE 617 ? A PHE 642 
372  1 Y 1 R PHE 618 ? A PHE 643 
373  1 Y 1 R LYS 619 ? A LYS 644 
374  1 Y 1 R ASP 620 ? A ASP 645 
375  1 Y 1 R ASP 621 ? A ASP 646 
376  1 Y 1 R GLY 622 ? A GLY 647 
377  1 Y 1 R ASN 623 ? A ASN 648 
378  1 Y 1 R TYR 624 ? A TYR 649 
379  1 Y 1 R LYS 625 ? A LYS 650 
380  1 Y 1 R THR 626 ? A THR 651 
381  1 Y 1 R ARG 627 ? A ARG 652 
382  1 Y 1 R ALA 628 ? A ALA 653 
383  1 Y 1 R GLU 629 ? A GLU 654 
384  1 Y 1 R VAL 630 ? A VAL 655 
385  1 Y 1 R LYS 631 ? A LYS 656 
386  1 Y 1 R PHE 632 ? A PHE 657 
387  1 Y 1 R GLU 633 ? A GLU 658 
388  1 Y 1 R GLY 634 ? A GLY 659 
389  1 Y 1 R ASP 635 ? A ASP 660 
390  1 Y 1 R THR 636 ? A THR 661 
391  1 Y 1 R LEU 637 ? A LEU 662 
392  1 Y 1 R VAL 638 ? A VAL 663 
393  1 Y 1 R ASN 639 ? A ASN 664 
394  1 Y 1 R ARG 640 ? A ARG 665 
395  1 Y 1 R ILE 641 ? A ILE 666 
396  1 Y 1 R GLU 642 ? A GLU 667 
397  1 Y 1 R LEU 643 ? A LEU 668 
398  1 Y 1 R LYS 644 ? A LYS 669 
399  1 Y 1 R GLY 645 ? A GLY 670 
400  1 Y 1 R ILE 646 ? A ILE 671 
401  1 Y 1 R ASP 647 ? A ASP 672 
402  1 Y 1 R PHE 648 ? A PHE 673 
403  1 Y 1 R LYS 649 ? A LYS 674 
404  1 Y 1 R GLU 650 ? A GLU 675 
405  1 Y 1 R ASP 651 ? A ASP 676 
406  1 Y 1 R GLY 652 ? A GLY 677 
407  1 Y 1 R ASN 653 ? A ASN 678 
408  1 Y 1 R ILE 654 ? A ILE 679 
409  1 Y 1 R LEU 655 ? A LEU 680 
410  1 Y 1 R GLY 656 ? A GLY 681 
411  1 Y 1 R HIS 657 ? A HIS 682 
412  1 Y 1 R LYS 658 ? A LYS 683 
413  1 Y 1 R LEU 659 ? A LEU 684 
414  1 Y 1 R GLU 660 ? A GLU 685 
415  1 Y 1 R TYR 661 ? A TYR 686 
416  1 Y 1 R ASN 662 ? A ASN 687 
417  1 Y 1 R TYR 663 ? A TYR 688 
418  1 Y 1 R ASN 664 ? A ASN 689 
419  1 Y 1 R SER 665 ? A SER 690 
420  1 Y 1 R HIS 666 ? A HIS 691 
421  1 Y 1 R ASN 667 ? A ASN 692 
422  1 Y 1 R VAL 668 ? A VAL 693 
423  1 Y 1 R TYR 669 ? A TYR 694 
424  1 Y 1 R ILE 670 ? A ILE 695 
425  1 Y 1 R MET 671 ? A MET 696 
426  1 Y 1 R ALA 672 ? A ALA 697 
427  1 Y 1 R ASP 673 ? A ASP 698 
428  1 Y 1 R LYS 674 ? A LYS 699 
429  1 Y 1 R GLN 675 ? A GLN 700 
430  1 Y 1 R LYS 676 ? A LYS 701 
431  1 Y 1 R ASN 677 ? A ASN 702 
432  1 Y 1 R GLY 678 ? A GLY 703 
433  1 Y 1 R ILE 679 ? A ILE 704 
434  1 Y 1 R LYS 680 ? A LYS 705 
435  1 Y 1 R VAL 681 ? A VAL 706 
436  1 Y 1 R ASN 682 ? A ASN 707 
437  1 Y 1 R PHE 683 ? A PHE 708 
438  1 Y 1 R LYS 684 ? A LYS 709 
439  1 Y 1 R ILE 685 ? A ILE 710 
440  1 Y 1 R ARG 686 ? A ARG 711 
441  1 Y 1 R HIS 687 ? A HIS 712 
442  1 Y 1 R ASN 688 ? A ASN 713 
443  1 Y 1 R ILE 689 ? A ILE 714 
444  1 Y 1 R GLU 690 ? A GLU 715 
445  1 Y 1 R ASP 691 ? A ASP 716 
446  1 Y 1 R GLY 692 ? A GLY 717 
447  1 Y 1 R SER 693 ? A SER 718 
448  1 Y 1 R VAL 694 ? A VAL 719 
449  1 Y 1 R GLN 695 ? A GLN 720 
450  1 Y 1 R LEU 696 ? A LEU 721 
451  1 Y 1 R ALA 697 ? A ALA 722 
452  1 Y 1 R ASP 698 ? A ASP 723 
453  1 Y 1 R HIS 699 ? A HIS 724 
454  1 Y 1 R TYR 700 ? A TYR 725 
455  1 Y 1 R GLN 701 ? A GLN 726 
456  1 Y 1 R GLN 702 ? A GLN 727 
457  1 Y 1 R ASN 703 ? A ASN 728 
458  1 Y 1 R THR 704 ? A THR 729 
459  1 Y 1 R PRO 705 ? A PRO 730 
460  1 Y 1 R ILE 706 ? A ILE 731 
461  1 Y 1 R GLY 707 ? A GLY 732 
462  1 Y 1 R ASP 708 ? A ASP 733 
463  1 Y 1 R GLY 709 ? A GLY 734 
464  1 Y 1 R PRO 710 ? A PRO 735 
465  1 Y 1 R VAL 711 ? A VAL 736 
466  1 Y 1 R LEU 712 ? A LEU 737 
467  1 Y 1 R LEU 713 ? A LEU 738 
468  1 Y 1 R PRO 714 ? A PRO 739 
469  1 Y 1 R ASP 715 ? A ASP 740 
470  1 Y 1 R ASN 716 ? A ASN 741 
471  1 Y 1 R HIS 717 ? A HIS 742 
472  1 Y 1 R TYR 718 ? A TYR 743 
473  1 Y 1 R LEU 719 ? A LEU 744 
474  1 Y 1 R SER 720 ? A SER 745 
475  1 Y 1 R THR 721 ? A THR 746 
476  1 Y 1 R GLN 722 ? A GLN 747 
477  1 Y 1 R SER 723 ? A SER 748 
478  1 Y 1 R LYS 724 ? A LYS 749 
479  1 Y 1 R LEU 725 ? A LEU 750 
480  1 Y 1 R SER 726 ? A SER 751 
481  1 Y 1 R LYS 727 ? A LYS 752 
482  1 Y 1 R ASP 728 ? A ASP 753 
483  1 Y 1 R PRO 729 ? A PRO 754 
484  1 Y 1 R ASN 730 ? A ASN 755 
485  1 Y 1 R GLU 731 ? A GLU 756 
486  1 Y 1 R LYS 732 ? A LYS 757 
487  1 Y 1 R ARG 733 ? A ARG 758 
488  1 Y 1 R ASP 734 ? A ASP 759 
489  1 Y 1 R HIS 735 ? A HIS 760 
490  1 Y 1 R MET 736 ? A MET 761 
491  1 Y 1 R VAL 737 ? A VAL 762 
492  1 Y 1 R LEU 738 ? A LEU 763 
493  1 Y 1 R LEU 739 ? A LEU 764 
494  1 Y 1 R GLU 740 ? A GLU 765 
495  1 Y 1 R PHE 741 ? A PHE 766 
496  1 Y 1 R VAL 742 ? A VAL 767 
497  1 Y 1 R THR 743 ? A THR 768 
498  1 Y 1 R ALA 744 ? A ALA 769 
499  1 Y 1 R ALA 745 ? A ALA 770 
500  1 Y 1 R GLY 746 ? A GLY 771 
501  1 Y 1 R ILE 747 ? A ILE 772 
502  1 Y 1 R THR 748 ? A THR 773 
503  1 Y 1 R LEU 749 ? A LEU 774 
504  1 Y 1 R GLY 750 ? A GLY 775 
505  1 Y 1 R MET 751 ? A MET 776 
506  1 Y 1 R ASP 752 ? A ASP 777 
507  1 Y 1 R GLU 753 ? A GLU 778 
508  1 Y 1 R LEU 754 ? A LEU 779 
509  1 Y 1 R TYR 755 ? A TYR 780 
510  1 Y 1 R LYS 756 ? A LYS 781 
511  1 Y 1 R SER 757 ? A SER 782 
512  1 Y 1 R GLY 758 ? A GLY 783 
513  1 Y 1 R LEU 759 ? A LEU 784 
514  1 Y 1 R ARG 760 ? A ARG 785 
515  1 Y 1 R SER 761 ? A SER 786 
516  1 Y 1 R HIS 762 ? A HIS 787 
517  1 Y 1 R HIS 763 ? A HIS 788 
518  1 Y 1 R HIS 764 ? A HIS 789 
519  1 Y 1 R HIS 765 ? A HIS 790 
520  1 Y 1 R HIS 766 ? A HIS 791 
521  1 Y 1 R HIS 767 ? A HIS 792 
522  1 Y 1 R HIS 768 ? A HIS 793 
523  1 Y 1 R HIS 769 ? A HIS 794 
524  1 Y 1 A MET -78 ? B MET 1   
525  1 Y 1 A ALA -77 ? B ALA 2   
526  1 Y 1 A SER -76 ? B SER 3   
527  1 Y 1 A ASN -75 ? B ASN 4   
528  1 Y 1 A ASN -74 ? B ASN 5   
529  1 Y 1 A THR -73 ? B THR 6   
530  1 Y 1 A ALA -72 ? B ALA 7   
531  1 Y 1 A SER -71 ? B SER 8   
532  1 Y 1 A ILE -70 ? B ILE 9   
533  1 Y 1 A ALA -69 ? B ALA 10  
534  1 Y 1 A GLN -68 ? B GLN 11  
535  1 Y 1 A ALA -67 ? B ALA 12  
536  1 Y 1 A ARG -66 ? B ARG 13  
537  1 Y 1 A LYS -65 ? B LYS 14  
538  1 Y 1 A LEU -64 ? B LEU 15  
539  1 Y 1 A VAL -63 ? B VAL 16  
540  1 Y 1 A GLU -62 ? B GLU 17  
541  1 Y 1 A GLN -61 ? B GLN 18  
542  1 Y 1 A LEU -60 ? B LEU 19  
543  1 Y 1 A LYS -59 ? B LYS 20  
544  1 Y 1 A MET -58 ? B MET 21  
545  1 Y 1 A GLU -57 ? B GLU 22  
546  1 Y 1 A ALA -56 ? B ALA 23  
547  1 Y 1 A ASN -55 ? B ASN 24  
548  1 Y 1 A ILE -54 ? B ILE 25  
549  1 Y 1 A ASP -53 ? B ASP 26  
550  1 Y 1 A ARG -52 ? B ARG 27  
551  1 Y 1 A ILE -51 ? B ILE 28  
552  1 Y 1 A LYS -50 ? B LYS 29  
553  1 Y 1 A VAL -49 ? B VAL 30  
554  1 Y 1 A SER -48 ? B SER 31  
555  1 Y 1 A LYS -47 ? B LYS 32  
556  1 Y 1 A ALA -46 ? B ALA 33  
557  1 Y 1 A ALA -45 ? B ALA 34  
558  1 Y 1 A ALA -44 ? B ALA 35  
559  1 Y 1 A ASP -43 ? B ASP 36  
560  1 Y 1 A LEU -42 ? B LEU 37  
561  1 Y 1 A MET -41 ? B MET 38  
562  1 Y 1 A ALA -40 ? B ALA 39  
563  1 Y 1 A TYR -39 ? B TYR 40  
564  1 Y 1 A CYS -38 ? B CYS 41  
565  1 Y 1 A GLU -37 ? B GLU 42  
566  1 Y 1 A ALA -36 ? B ALA 43  
567  1 Y 1 A HIS -35 ? B HIS 44  
568  1 Y 1 A ALA -34 ? B ALA 45  
569  1 Y 1 A LYS -33 ? B LYS 46  
570  1 Y 1 A GLU -32 ? B GLU 47  
571  1 Y 1 A ASP -31 ? B ASP 48  
572  1 Y 1 A PRO -30 ? B PRO 49  
573  1 Y 1 A LEU -29 ? B LEU 50  
574  1 Y 1 A LEU -28 ? B LEU 51  
575  1 Y 1 A THR -27 ? B THR 52  
576  1 Y 1 A PRO -26 ? B PRO 53  
577  1 Y 1 A VAL -25 ? B VAL 54  
578  1 Y 1 A PRO -24 ? B PRO 55  
579  1 Y 1 A ALA -23 ? B ALA 56  
580  1 Y 1 A SER -22 ? B SER 57  
581  1 Y 1 A GLU -21 ? B GLU 58  
582  1 Y 1 A ASN -20 ? B ASN 59  
583  1 Y 1 A PRO -19 ? B PRO 60  
584  1 Y 1 A PHE -18 ? B PHE 61  
585  1 Y 1 A ARG -17 ? B ARG 62  
586  1 Y 1 A GLU -16 ? B GLU 63  
587  1 Y 1 A LYS -15 ? B LYS 64  
588  1 Y 1 A LYS -14 ? B LYS 65  
589  1 Y 1 A PHE -13 ? B PHE 66  
590  1 Y 1 A PHE -12 ? B PHE 67  
591  1 Y 1 A CYS -11 ? B CYS 68  
592  1 Y 1 A ALA -10 ? B ALA 69  
593  1 Y 1 A ILE -9  ? B ILE 70  
594  1 Y 1 A LEU -8  ? B LEU 71  
595  1 Y 1 A GLY -7  ? B GLY 72  
596  1 Y 1 A SER -6  ? B SER 73  
597  1 Y 1 A ALA -5  ? B ALA 74  
598  1 Y 1 A GLY -4  ? B GLY 75  
599  1 Y 1 A SER -3  ? B SER 76  
600  1 Y 1 A ALA -2  ? B ALA 77  
601  1 Y 1 A GLY -1  ? B GLY 78  
602  1 Y 1 A SER 0   ? B SER 79  
603  1 Y 1 A ALA 1   ? B ALA 80  
604  1 Y 1 A MET 2   ? B MET 81  
605  1 Y 1 A CYS 3   ? B CYS 82  
606  1 Y 1 A ILE 55  ? B ILE 134 
607  1 Y 1 A ILE 56  ? B ILE 135 
608  1 Y 1 A HIS 57  ? B HIS 136 
609  1 Y 1 A GLU 58  ? B GLU 137 
610  1 Y 1 A ALA 59  ? B ALA 138 
611  1 Y 1 A GLY 60  ? B GLY 139 
612  1 Y 1 A TYR 61  ? B TYR 140 
613  1 Y 1 A SER 62  ? B SER 141 
614  1 Y 1 A GLU 63  ? B GLU 142 
615  1 Y 1 A GLU 64  ? B GLU 143 
616  1 Y 1 A GLU 65  ? B GLU 144 
617  1 Y 1 A CYS 66  ? B CYS 145 
618  1 Y 1 A LYS 67  ? B LYS 146 
619  1 Y 1 A GLN 68  ? B GLN 147 
620  1 Y 1 A TYR 69  ? B TYR 148 
621  1 Y 1 A LYS 70  ? B LYS 149 
622  1 Y 1 A ALA 71  ? B ALA 150 
623  1 Y 1 A VAL 72  ? B VAL 151 
624  1 Y 1 A VAL 73  ? B VAL 152 
625  1 Y 1 A TYR 74  ? B TYR 153 
626  1 Y 1 A SER 75  ? B SER 154 
627  1 Y 1 A ASN 76  ? B ASN 155 
628  1 Y 1 A THR 77  ? B THR 156 
629  1 Y 1 A ILE 78  ? B ILE 157 
630  1 Y 1 A GLN 79  ? B GLN 158 
631  1 Y 1 A SER 80  ? B SER 159 
632  1 Y 1 A ILE 81  ? B ILE 160 
633  1 Y 1 A ILE 82  ? B ILE 161 
634  1 Y 1 A ALA 83  ? B ALA 162 
635  1 Y 1 A ILE 84  ? B ILE 163 
636  1 Y 1 A ILE 85  ? B ILE 164 
637  1 Y 1 A ARG 86  ? B ARG 165 
638  1 Y 1 A ALA 87  ? B ALA 166 
639  1 Y 1 A MET 88  ? B MET 167 
640  1 Y 1 A GLY 89  ? B GLY 168 
641  1 Y 1 A ARG 90  ? B ARG 169 
642  1 Y 1 A LEU 91  ? B LEU 170 
643  1 Y 1 A LYS 92  ? B LYS 171 
644  1 Y 1 A ILE 93  ? B ILE 172 
645  1 Y 1 A ASP 94  ? B ASP 173 
646  1 Y 1 A PHE 95  ? B PHE 174 
647  1 Y 1 A GLY 96  ? B GLY 175 
648  1 Y 1 A ASP 97  ? B ASP 176 
649  1 Y 1 A SER 98  ? B SER 177 
650  1 Y 1 A ALA 99  ? B ALA 178 
651  1 Y 1 A ARG 100 ? B ARG 179 
652  1 Y 1 A ALA 101 ? B ALA 180 
653  1 Y 1 A ASP 102 ? B ASP 181 
654  1 Y 1 A ASP 103 ? B ASP 182 
655  1 Y 1 A ALA 104 ? B ALA 183 
656  1 Y 1 A ARG 105 ? B ARG 184 
657  1 Y 1 A GLN 106 ? B GLN 185 
658  1 Y 1 A LEU 107 ? B LEU 186 
659  1 Y 1 A PHE 108 ? B PHE 187 
660  1 Y 1 A VAL 109 ? B VAL 188 
661  1 Y 1 A LEU 110 ? B LEU 189 
662  1 Y 1 A ALA 111 ? B ALA 190 
663  1 Y 1 A GLY 112 ? B GLY 191 
664  1 Y 1 A ALA 113 ? B ALA 192 
665  1 Y 1 A ALA 114 ? B ALA 193 
666  1 Y 1 A GLU 115 ? B GLU 194 
667  1 Y 1 A GLU 116 ? B GLU 195 
668  1 Y 1 A GLY 117 ? B GLY 196 
669  1 Y 1 A PHE 118 ? B PHE 197 
670  1 Y 1 A MET 119 ? B MET 198 
671  1 Y 1 A THR 120 ? B THR 199 
672  1 Y 1 A ALA 121 ? B ALA 200 
673  1 Y 1 A GLU 122 ? B GLU 201 
674  1 Y 1 A LEU 123 ? B LEU 202 
675  1 Y 1 A ALA 124 ? B ALA 203 
676  1 Y 1 A GLY 125 ? B GLY 204 
677  1 Y 1 A VAL 126 ? B VAL 205 
678  1 Y 1 A ILE 127 ? B ILE 206 
679  1 Y 1 A LYS 128 ? B LYS 207 
680  1 Y 1 A ARG 129 ? B ARG 208 
681  1 Y 1 A LEU 130 ? B LEU 209 
682  1 Y 1 A TRP 131 ? B TRP 210 
683  1 Y 1 A LYS 132 ? B LYS 211 
684  1 Y 1 A ASP 133 ? B ASP 212 
685  1 Y 1 A SER 134 ? B SER 213 
686  1 Y 1 A GLY 135 ? B GLY 214 
687  1 Y 1 A VAL 136 ? B VAL 215 
688  1 Y 1 A GLN 137 ? B GLN 216 
689  1 Y 1 A ALA 138 ? B ALA 217 
690  1 Y 1 A CYS 139 ? B CYS 218 
691  1 Y 1 A PHE 140 ? B PHE 219 
692  1 Y 1 A ASN 141 ? B ASN 220 
693  1 Y 1 A ARG 142 ? B ARG 221 
694  1 Y 1 A SER 143 ? B SER 222 
695  1 Y 1 A ARG 144 ? B ARG 223 
696  1 Y 1 A GLU 145 ? B GLU 224 
697  1 Y 1 A TYR 146 ? B TYR 225 
698  1 Y 1 A GLN 147 ? B GLN 226 
699  1 Y 1 A LEU 148 ? B LEU 227 
700  1 Y 1 A ASN 149 ? B ASN 228 
701  1 Y 1 A ASP 150 ? B ASP 229 
702  1 Y 1 A SER 151 ? B SER 230 
703  1 Y 1 A ALA 152 ? B ALA 231 
704  1 Y 1 A ALA 153 ? B ALA 232 
705  1 Y 1 A TYR 154 ? B TYR 233 
706  1 Y 1 A TYR 155 ? B TYR 234 
707  1 Y 1 A LEU 156 ? B LEU 235 
708  1 Y 1 A ASN 157 ? B ASN 236 
709  1 Y 1 A ASP 158 ? B ASP 237 
710  1 Y 1 A LEU 159 ? B LEU 238 
711  1 Y 1 A ASP 160 ? B ASP 239 
712  1 Y 1 A ARG 161 ? B ARG 240 
713  1 Y 1 A ILE 162 ? B ILE 241 
714  1 Y 1 A ALA 163 ? B ALA 242 
715  1 Y 1 A GLN 164 ? B GLN 243 
716  1 Y 1 A PRO 165 ? B PRO 244 
717  1 Y 1 A ASN 166 ? B ASN 245 
718  1 Y 1 A TYR 167 ? B TYR 246 
719  1 Y 1 A ILE 168 ? B ILE 247 
720  1 Y 1 A PRO 169 ? B PRO 248 
721  1 Y 1 A THR 170 ? B THR 249 
722  1 Y 1 A GLN 171 ? B GLN 250 
723  1 Y 1 A GLN 172 ? B GLN 251 
724  1 Y 1 A ASP 173 ? B ASP 252 
725  1 Y 1 A VAL 174 ? B VAL 253 
726  1 Y 1 A LEU 175 ? B LEU 254 
727  1 Y 1 A ARG 176 ? B ARG 255 
728  1 Y 1 A THR 177 ? B THR 256 
729  1 Y 1 A ARG 178 ? B ARG 257 
730  1 Y 1 A VAL 179 ? B VAL 258 
731  1 Y 1 A LYS 180 ? B LYS 259 
732  1 Y 1 A THR 181 ? B THR 260 
733  1 Y 1 A THR 182 ? B THR 261 
734  1 Y 1 A ASP 229 ? B ASP 308 
735  1 Y 1 A TYR 230 ? B TYR 309 
736  1 Y 1 A ASP 231 ? B ASP 310 
737  1 Y 1 A LEU 232 ? B LEU 311 
738  1 Y 1 A VAL 233 ? B VAL 312 
739  1 Y 1 A LEU 234 ? B LEU 313 
740  1 Y 1 A ALA 235 ? B ALA 314 
741  1 Y 1 A GLU 236 ? B GLU 315 
742  1 Y 1 A ASP 237 ? B ASP 316 
743  1 Y 1 A GLU 238 ? B GLU 317 
744  1 Y 1 A GLU 239 ? B GLU 318 
745  1 Y 1 A MET 240 ? B MET 319 
746  1 Y 1 B MET -4  ? C MET 1   
747  1 Y 1 B GLY -3  ? C GLY 2   
748  1 Y 1 B SER -2  ? C SER 3   
749  1 Y 1 B LEU -1  ? C LEU 4   
750  1 Y 1 B LEU 0   ? C LEU 5   
751  1 Y 1 B GLN 1   ? C GLN 6   
752  1 Y 1 B SER 2   ? C SER 7   
753  1 Y 1 B GLU 3   ? C GLU 8   
754  1 Y 1 B LEU 4   ? C LEU 9   
755  1 Y 1 B GLY 341 ? C GLY 346 
756  1 Y 1 B ALA 342 ? C ALA 347 
757  1 Y 1 B SER 343 ? C SER 348 
758  1 Y 1 B GLY 344 ? C GLY 349 
759  1 Y 1 B GLY 345 ? C GLY 350 
760  1 Y 1 B GLY 346 ? C GLY 351 
761  1 Y 1 B SER 347 ? C SER 352 
762  1 Y 1 B GLY 348 ? C GLY 353 
763  1 Y 1 B GLY 349 ? C GLY 354 
764  1 Y 1 B ASN 350 ? C ASN 355 
765  1 Y 1 B SER 351 ? C SER 356 
766  1 Y 1 B GLY 352 ? C GLY 357 
767  1 Y 1 B SER 353 ? C SER 358 
768  1 Y 1 B SER 354 ? C SER 359 
769  1 Y 1 B GLY 355 ? C GLY 360 
770  1 Y 1 B GLY 356 ? C GLY 361 
771  1 Y 1 B SER 357 ? C SER 362 
772  1 Y 1 B SER 358 ? C SER 363 
773  1 Y 1 B GLY 359 ? C GLY 364 
774  1 Y 1 B VAL 360 ? C VAL 365 
775  1 Y 1 B SER 361 ? C SER 366 
776  1 Y 1 B GLY 362 ? C GLY 367 
777  1 Y 1 B TRP 363 ? C TRP 368 
778  1 Y 1 B ARG 364 ? C ARG 369 
779  1 Y 1 B LEU 365 ? C LEU 370 
780  1 Y 1 B PHE 366 ? C PHE 371 
781  1 Y 1 B LYS 367 ? C LYS 372 
782  1 Y 1 B LYS 368 ? C LYS 373 
783  1 Y 1 B ILE 369 ? C ILE 374 
784  1 Y 1 B SER 370 ? C SER 375 
785  1 Y 1 G MET 1   ? D MET 1   
786  1 Y 1 G ALA 2   ? D ALA 2   
787  1 Y 1 G SER 3   ? D SER 3   
788  1 Y 1 G ASN 4   ? D ASN 4   
789  1 Y 1 G ASN 5   ? D ASN 5   
790  1 Y 1 G THR 6   ? D THR 6   
791  1 Y 1 G ALA 7   ? D ALA 7   
792  1 Y 1 G SER 8   ? D SER 8   
793  1 Y 1 G ARG 62  ? D ARG 62  
794  1 Y 1 G GLU 63  ? D GLU 63  
795  1 Y 1 G LYS 64  ? D LYS 64  
796  1 Y 1 G LYS 65  ? D LYS 65  
797  1 Y 1 G PHE 66  ? D PHE 66  
798  1 Y 1 G PHE 67  ? D PHE 67  
799  1 Y 1 G CYS 68  ? D CYS 68  
800  1 Y 1 G ALA 69  ? D ALA 69  
801  1 Y 1 G ILE 70  ? D ILE 70  
802  1 Y 1 G LEU 71  ? D LEU 71  
803  1 Y 1 G GLY 72  ? D GLY 72  
804  1 Y 1 G SER 73  ? D SER 73  
805  1 Y 1 G ALA 74  ? D ALA 74  
806  1 Y 1 G GLY 75  ? D GLY 75  
807  1 Y 1 G SER 76  ? D SER 76  
808  1 Y 1 G ALA 77  ? D ALA 77  
809  1 Y 1 G GLY 78  ? D GLY 78  
810  1 Y 1 G SER 79  ? D SER 79  
811  1 Y 1 G ALA 80  ? D ALA 80  
812  1 Y 1 G MET 81  ? D MET 81  
813  1 Y 1 G CYS 82  ? D CYS 82  
814  1 Y 1 G THR 83  ? D THR 83  
815  1 Y 1 G LEU 84  ? D LEU 84  
816  1 Y 1 G SER 85  ? D SER 85  
817  1 Y 1 G ALA 86  ? D ALA 86  
818  1 Y 1 G GLU 87  ? D GLU 87  
819  1 Y 1 G ASP 88  ? D ASP 88  
820  1 Y 1 G LYS 89  ? D LYS 89  
821  1 Y 1 G ALA 90  ? D ALA 90  
822  1 Y 1 G ALA 91  ? D ALA 91  
823  1 Y 1 G VAL 92  ? D VAL 92  
824  1 Y 1 G GLU 93  ? D GLU 93  
825  1 Y 1 G ARG 94  ? D ARG 94  
826  1 Y 1 G SER 95  ? D SER 95  
827  1 Y 1 G LYS 96  ? D LYS 96  
828  1 Y 1 G MET 97  ? D MET 97  
829  1 Y 1 G ILE 98  ? D ILE 98  
830  1 Y 1 G ASP 99  ? D ASP 99  
831  1 Y 1 G ARG 100 ? D ARG 100 
832  1 Y 1 G ASN 101 ? D ASN 101 
833  1 Y 1 G LEU 102 ? D LEU 102 
834  1 Y 1 G ARG 103 ? D ARG 103 
835  1 Y 1 G GLU 104 ? D GLU 104 
836  1 Y 1 G ASP 105 ? D ASP 105 
837  1 Y 1 G GLY 106 ? D GLY 106 
838  1 Y 1 G GLU 107 ? D GLU 107 
839  1 Y 1 G LYS 108 ? D LYS 108 
840  1 Y 1 G ALA 109 ? D ALA 109 
841  1 Y 1 G ALA 110 ? D ALA 110 
842  1 Y 1 G ARG 111 ? D ARG 111 
843  1 Y 1 G GLU 112 ? D GLU 112 
844  1 Y 1 G VAL 113 ? D VAL 113 
845  1 Y 1 G LYS 114 ? D LYS 114 
846  1 Y 1 G LEU 115 ? D LEU 115 
847  1 Y 1 G LEU 116 ? D LEU 116 
848  1 Y 1 G LEU 117 ? D LEU 117 
849  1 Y 1 G LEU 118 ? D LEU 118 
850  1 Y 1 G GLY 119 ? D GLY 119 
851  1 Y 1 G ALA 120 ? D ALA 120 
852  1 Y 1 G GLY 121 ? D GLY 121 
853  1 Y 1 G GLU 122 ? D GLU 122 
854  1 Y 1 G SER 123 ? D SER 123 
855  1 Y 1 G GLY 124 ? D GLY 124 
856  1 Y 1 G LYS 125 ? D LYS 125 
857  1 Y 1 G SER 126 ? D SER 126 
858  1 Y 1 G THR 127 ? D THR 127 
859  1 Y 1 G ILE 128 ? D ILE 128 
860  1 Y 1 G VAL 129 ? D VAL 129 
861  1 Y 1 G LYS 130 ? D LYS 130 
862  1 Y 1 G GLN 131 ? D GLN 131 
863  1 Y 1 G MET 132 ? D MET 132 
864  1 Y 1 G LYS 133 ? D LYS 133 
865  1 Y 1 G ILE 134 ? D ILE 134 
866  1 Y 1 G ILE 135 ? D ILE 135 
867  1 Y 1 G HIS 136 ? D HIS 136 
868  1 Y 1 G GLU 137 ? D GLU 137 
869  1 Y 1 G ALA 138 ? D ALA 138 
870  1 Y 1 G GLY 139 ? D GLY 139 
871  1 Y 1 G TYR 140 ? D TYR 140 
872  1 Y 1 G SER 141 ? D SER 141 
873  1 Y 1 G GLU 142 ? D GLU 142 
874  1 Y 1 G GLU 143 ? D GLU 143 
875  1 Y 1 G GLU 144 ? D GLU 144 
876  1 Y 1 G CYS 145 ? D CYS 145 
877  1 Y 1 G LYS 146 ? D LYS 146 
878  1 Y 1 G GLN 147 ? D GLN 147 
879  1 Y 1 G TYR 148 ? D TYR 148 
880  1 Y 1 G LYS 149 ? D LYS 149 
881  1 Y 1 G ALA 150 ? D ALA 150 
882  1 Y 1 G VAL 151 ? D VAL 151 
883  1 Y 1 G VAL 152 ? D VAL 152 
884  1 Y 1 G TYR 153 ? D TYR 153 
885  1 Y 1 G SER 154 ? D SER 154 
886  1 Y 1 G ASN 155 ? D ASN 155 
887  1 Y 1 G THR 156 ? D THR 156 
888  1 Y 1 G ILE 157 ? D ILE 157 
889  1 Y 1 G GLN 158 ? D GLN 158 
890  1 Y 1 G SER 159 ? D SER 159 
891  1 Y 1 G ILE 160 ? D ILE 160 
892  1 Y 1 G ILE 161 ? D ILE 161 
893  1 Y 1 G ALA 162 ? D ALA 162 
894  1 Y 1 G ILE 163 ? D ILE 163 
895  1 Y 1 G ILE 164 ? D ILE 164 
896  1 Y 1 G ARG 165 ? D ARG 165 
897  1 Y 1 G ALA 166 ? D ALA 166 
898  1 Y 1 G MET 167 ? D MET 167 
899  1 Y 1 G GLY 168 ? D GLY 168 
900  1 Y 1 G ARG 169 ? D ARG 169 
901  1 Y 1 G LEU 170 ? D LEU 170 
902  1 Y 1 G LYS 171 ? D LYS 171 
903  1 Y 1 G ILE 172 ? D ILE 172 
904  1 Y 1 G ASP 173 ? D ASP 173 
905  1 Y 1 G PHE 174 ? D PHE 174 
906  1 Y 1 G GLY 175 ? D GLY 175 
907  1 Y 1 G ASP 176 ? D ASP 176 
908  1 Y 1 G SER 177 ? D SER 177 
909  1 Y 1 G ALA 178 ? D ALA 178 
910  1 Y 1 G ARG 179 ? D ARG 179 
911  1 Y 1 G ALA 180 ? D ALA 180 
912  1 Y 1 G ASP 181 ? D ASP 181 
913  1 Y 1 G ASP 182 ? D ASP 182 
914  1 Y 1 G ALA 183 ? D ALA 183 
915  1 Y 1 G ARG 184 ? D ARG 184 
916  1 Y 1 G GLN 185 ? D GLN 185 
917  1 Y 1 G LEU 186 ? D LEU 186 
918  1 Y 1 G PHE 187 ? D PHE 187 
919  1 Y 1 G VAL 188 ? D VAL 188 
920  1 Y 1 G LEU 189 ? D LEU 189 
921  1 Y 1 G ALA 190 ? D ALA 190 
922  1 Y 1 G GLY 191 ? D GLY 191 
923  1 Y 1 G ALA 192 ? D ALA 192 
924  1 Y 1 G ALA 193 ? D ALA 193 
925  1 Y 1 G GLU 194 ? D GLU 194 
926  1 Y 1 G GLU 195 ? D GLU 195 
927  1 Y 1 G GLY 196 ? D GLY 196 
928  1 Y 1 G PHE 197 ? D PHE 197 
929  1 Y 1 G MET 198 ? D MET 198 
930  1 Y 1 G THR 199 ? D THR 199 
931  1 Y 1 G ALA 200 ? D ALA 200 
932  1 Y 1 G GLU 201 ? D GLU 201 
933  1 Y 1 G LEU 202 ? D LEU 202 
934  1 Y 1 G ALA 203 ? D ALA 203 
935  1 Y 1 G GLY 204 ? D GLY 204 
936  1 Y 1 G VAL 205 ? D VAL 205 
937  1 Y 1 G ILE 206 ? D ILE 206 
938  1 Y 1 G LYS 207 ? D LYS 207 
939  1 Y 1 G ARG 208 ? D ARG 208 
940  1 Y 1 G LEU 209 ? D LEU 209 
941  1 Y 1 G TRP 210 ? D TRP 210 
942  1 Y 1 G LYS 211 ? D LYS 211 
943  1 Y 1 G ASP 212 ? D ASP 212 
944  1 Y 1 G SER 213 ? D SER 213 
945  1 Y 1 G GLY 214 ? D GLY 214 
946  1 Y 1 G VAL 215 ? D VAL 215 
947  1 Y 1 G GLN 216 ? D GLN 216 
948  1 Y 1 G ALA 217 ? D ALA 217 
949  1 Y 1 G CYS 218 ? D CYS 218 
950  1 Y 1 G PHE 219 ? D PHE 219 
951  1 Y 1 G ASN 220 ? D ASN 220 
952  1 Y 1 G ARG 221 ? D ARG 221 
953  1 Y 1 G SER 222 ? D SER 222 
954  1 Y 1 G ARG 223 ? D ARG 223 
955  1 Y 1 G GLU 224 ? D GLU 224 
956  1 Y 1 G TYR 225 ? D TYR 225 
957  1 Y 1 G GLN 226 ? D GLN 226 
958  1 Y 1 G LEU 227 ? D LEU 227 
959  1 Y 1 G ASN 228 ? D ASN 228 
960  1 Y 1 G ASP 229 ? D ASP 229 
961  1 Y 1 G SER 230 ? D SER 230 
962  1 Y 1 G ALA 231 ? D ALA 231 
963  1 Y 1 G ALA 232 ? D ALA 232 
964  1 Y 1 G TYR 233 ? D TYR 233 
965  1 Y 1 G TYR 234 ? D TYR 234 
966  1 Y 1 G LEU 235 ? D LEU 235 
967  1 Y 1 G ASN 236 ? D ASN 236 
968  1 Y 1 G ASP 237 ? D ASP 237 
969  1 Y 1 G LEU 238 ? D LEU 238 
970  1 Y 1 G ASP 239 ? D ASP 239 
971  1 Y 1 G ARG 240 ? D ARG 240 
972  1 Y 1 G ILE 241 ? D ILE 241 
973  1 Y 1 G ALA 242 ? D ALA 242 
974  1 Y 1 G GLN 243 ? D GLN 243 
975  1 Y 1 G PRO 244 ? D PRO 244 
976  1 Y 1 G ASN 245 ? D ASN 245 
977  1 Y 1 G TYR 246 ? D TYR 246 
978  1 Y 1 G ILE 247 ? D ILE 247 
979  1 Y 1 G PRO 248 ? D PRO 248 
980  1 Y 1 G THR 249 ? D THR 249 
981  1 Y 1 G GLN 250 ? D GLN 250 
982  1 Y 1 G GLN 251 ? D GLN 251 
983  1 Y 1 G ASP 252 ? D ASP 252 
984  1 Y 1 G VAL 253 ? D VAL 253 
985  1 Y 1 G LEU 254 ? D LEU 254 
986  1 Y 1 G ARG 255 ? D ARG 255 
987  1 Y 1 G THR 256 ? D THR 256 
988  1 Y 1 G ARG 257 ? D ARG 257 
989  1 Y 1 G VAL 258 ? D VAL 258 
990  1 Y 1 G LYS 259 ? D LYS 259 
991  1 Y 1 G THR 260 ? D THR 260 
992  1 Y 1 G THR 261 ? D THR 261 
993  1 Y 1 G GLY 262 ? D GLY 262 
994  1 Y 1 G ILE 263 ? D ILE 263 
995  1 Y 1 G VAL 264 ? D VAL 264 
996  1 Y 1 G GLU 265 ? D GLU 265 
997  1 Y 1 G THR 266 ? D THR 266 
998  1 Y 1 G HIS 267 ? D HIS 267 
999  1 Y 1 G PHE 268 ? D PHE 268 
1000 1 Y 1 G THR 269 ? D THR 269 
1001 1 Y 1 G PHE 270 ? D PHE 270 
1002 1 Y 1 G LYS 271 ? D LYS 271 
1003 1 Y 1 G ASP 272 ? D ASP 272 
1004 1 Y 1 G LEU 273 ? D LEU 273 
1005 1 Y 1 G HIS 274 ? D HIS 274 
1006 1 Y 1 G PHE 275 ? D PHE 275 
1007 1 Y 1 G LYS 276 ? D LYS 276 
1008 1 Y 1 G MET 277 ? D MET 277 
1009 1 Y 1 G PHE 278 ? D PHE 278 
1010 1 Y 1 G ASP 279 ? D ASP 279 
1011 1 Y 1 G VAL 280 ? D VAL 280 
1012 1 Y 1 G GLY 281 ? D GLY 281 
1013 1 Y 1 G GLY 282 ? D GLY 282 
1014 1 Y 1 G GLN 283 ? D GLN 283 
1015 1 Y 1 G ARG 284 ? D ARG 284 
1016 1 Y 1 G SER 285 ? D SER 285 
1017 1 Y 1 G GLU 286 ? D GLU 286 
1018 1 Y 1 G ARG 287 ? D ARG 287 
1019 1 Y 1 G LYS 288 ? D LYS 288 
1020 1 Y 1 G LYS 289 ? D LYS 289 
1021 1 Y 1 G TRP 290 ? D TRP 290 
1022 1 Y 1 G ILE 291 ? D ILE 291 
1023 1 Y 1 G HIS 292 ? D HIS 292 
1024 1 Y 1 G CYS 293 ? D CYS 293 
1025 1 Y 1 G PHE 294 ? D PHE 294 
1026 1 Y 1 G GLU 295 ? D GLU 295 
1027 1 Y 1 G GLY 296 ? D GLY 296 
1028 1 Y 1 G VAL 297 ? D VAL 297 
1029 1 Y 1 G THR 298 ? D THR 298 
1030 1 Y 1 G ALA 299 ? D ALA 299 
1031 1 Y 1 G ILE 300 ? D ILE 300 
1032 1 Y 1 G ILE 301 ? D ILE 301 
1033 1 Y 1 G PHE 302 ? D PHE 302 
1034 1 Y 1 G CYS 303 ? D CYS 303 
1035 1 Y 1 G VAL 304 ? D VAL 304 
1036 1 Y 1 G ALA 305 ? D ALA 305 
1037 1 Y 1 G LEU 306 ? D LEU 306 
1038 1 Y 1 G SER 307 ? D SER 307 
1039 1 Y 1 G ASP 308 ? D ASP 308 
1040 1 Y 1 G TYR 309 ? D TYR 309 
1041 1 Y 1 G ASP 310 ? D ASP 310 
1042 1 Y 1 G LEU 311 ? D LEU 311 
1043 1 Y 1 G VAL 312 ? D VAL 312 
1044 1 Y 1 G LEU 313 ? D LEU 313 
1045 1 Y 1 G ALA 314 ? D ALA 314 
1046 1 Y 1 G GLU 315 ? D GLU 315 
1047 1 Y 1 G ASP 316 ? D ASP 316 
1048 1 Y 1 G GLU 317 ? D GLU 317 
1049 1 Y 1 G GLU 318 ? D GLU 318 
1050 1 Y 1 G MET 319 ? D MET 319 
1051 1 Y 1 G ASN 320 ? D ASN 320 
1052 1 Y 1 G ARG 321 ? D ARG 321 
1053 1 Y 1 G MET 322 ? D MET 322 
1054 1 Y 1 G HIS 323 ? D HIS 323 
1055 1 Y 1 G GLU 324 ? D GLU 324 
1056 1 Y 1 G SER 325 ? D SER 325 
1057 1 Y 1 G MET 326 ? D MET 326 
1058 1 Y 1 G LYS 327 ? D LYS 327 
1059 1 Y 1 G LEU 328 ? D LEU 328 
1060 1 Y 1 G PHE 329 ? D PHE 329 
1061 1 Y 1 G ASP 330 ? D ASP 330 
1062 1 Y 1 G SER 331 ? D SER 331 
1063 1 Y 1 G ILE 332 ? D ILE 332 
1064 1 Y 1 G CYS 333 ? D CYS 333 
1065 1 Y 1 G ASN 334 ? D ASN 334 
1066 1 Y 1 G ASN 335 ? D ASN 335 
1067 1 Y 1 G LYS 336 ? D LYS 336 
1068 1 Y 1 G TRP 337 ? D TRP 337 
1069 1 Y 1 G PHE 338 ? D PHE 338 
1070 1 Y 1 G THR 339 ? D THR 339 
1071 1 Y 1 G ASP 340 ? D ASP 340 
1072 1 Y 1 G THR 341 ? D THR 341 
1073 1 Y 1 G SER 342 ? D SER 342 
1074 1 Y 1 G ILE 343 ? D ILE 343 
1075 1 Y 1 G ILE 344 ? D ILE 344 
1076 1 Y 1 G LEU 345 ? D LEU 345 
1077 1 Y 1 G PHE 346 ? D PHE 346 
1078 1 Y 1 G LEU 347 ? D LEU 347 
1079 1 Y 1 G ASN 348 ? D ASN 348 
1080 1 Y 1 G LYS 349 ? D LYS 349 
1081 1 Y 1 G LYS 350 ? D LYS 350 
1082 1 Y 1 G ASP 351 ? D ASP 351 
1083 1 Y 1 G LEU 352 ? D LEU 352 
1084 1 Y 1 G PHE 353 ? D PHE 353 
1085 1 Y 1 G GLU 354 ? D GLU 354 
1086 1 Y 1 G GLU 355 ? D GLU 355 
1087 1 Y 1 G LYS 356 ? D LYS 356 
1088 1 Y 1 G ILE 357 ? D ILE 357 
1089 1 Y 1 G LYS 358 ? D LYS 358 
1090 1 Y 1 G LYS 359 ? D LYS 359 
1091 1 Y 1 G SER 360 ? D SER 360 
1092 1 Y 1 G PRO 361 ? D PRO 361 
1093 1 Y 1 G LEU 362 ? D LEU 362 
1094 1 Y 1 G THR 363 ? D THR 363 
1095 1 Y 1 G ILE 364 ? D ILE 364 
1096 1 Y 1 G CYS 365 ? D CYS 365 
1097 1 Y 1 G TYR 366 ? D TYR 366 
1098 1 Y 1 G PRO 367 ? D PRO 367 
1099 1 Y 1 G GLU 368 ? D GLU 368 
1100 1 Y 1 G TYR 369 ? D TYR 369 
1101 1 Y 1 G ALA 370 ? D ALA 370 
1102 1 Y 1 G GLY 371 ? D GLY 371 
1103 1 Y 1 G SER 372 ? D SER 372 
1104 1 Y 1 G ASN 373 ? D ASN 373 
1105 1 Y 1 G THR 374 ? D THR 374 
1106 1 Y 1 G TYR 375 ? D TYR 375 
1107 1 Y 1 G GLU 376 ? D GLU 376 
1108 1 Y 1 G GLU 377 ? D GLU 377 
1109 1 Y 1 G ALA 378 ? D ALA 378 
1110 1 Y 1 G ALA 379 ? D ALA 379 
1111 1 Y 1 G ALA 380 ? D ALA 380 
1112 1 Y 1 G TYR 381 ? D TYR 381 
1113 1 Y 1 G ILE 382 ? D ILE 382 
1114 1 Y 1 G GLN 383 ? D GLN 383 
1115 1 Y 1 G CYS 384 ? D CYS 384 
1116 1 Y 1 G GLN 385 ? D GLN 385 
1117 1 Y 1 G PHE 386 ? D PHE 386 
1118 1 Y 1 G GLU 387 ? D GLU 387 
1119 1 Y 1 G ASP 388 ? D ASP 388 
1120 1 Y 1 G LEU 389 ? D LEU 389 
1121 1 Y 1 G ASN 390 ? D ASN 390 
1122 1 Y 1 G LYS 391 ? D LYS 391 
1123 1 Y 1 G ARG 392 ? D ARG 392 
1124 1 Y 1 G LYS 393 ? D LYS 393 
1125 1 Y 1 G ASP 394 ? D ASP 394 
1126 1 Y 1 G THR 395 ? D THR 395 
1127 1 Y 1 G LYS 396 ? D LYS 396 
1128 1 Y 1 G GLU 397 ? D GLU 397 
1129 1 Y 1 G ILE 398 ? D ILE 398 
1130 1 Y 1 G TYR 399 ? D TYR 399 
1131 1 Y 1 G THR 400 ? D THR 400 
1132 1 Y 1 G HIS 401 ? D HIS 401 
1133 1 Y 1 G PHE 402 ? D PHE 402 
1134 1 Y 1 G THR 403 ? D THR 403 
1135 1 Y 1 G CYS 404 ? D CYS 404 
1136 1 Y 1 G ALA 405 ? D ALA 405 
1137 1 Y 1 G THR 406 ? D THR 406 
1138 1 Y 1 G ASP 407 ? D ASP 407 
1139 1 Y 1 G THR 408 ? D THR 408 
1140 1 Y 1 G LYS 409 ? D LYS 409 
1141 1 Y 1 G ASN 410 ? D ASN 410 
1142 1 Y 1 G VAL 411 ? D VAL 411 
1143 1 Y 1 G GLN 412 ? D GLN 412 
1144 1 Y 1 G PHE 413 ? D PHE 413 
1145 1 Y 1 G VAL 414 ? D VAL 414 
1146 1 Y 1 G PHE 415 ? D PHE 415 
1147 1 Y 1 G ASP 416 ? D ASP 416 
1148 1 Y 1 G ALA 417 ? D ALA 417 
1149 1 Y 1 G VAL 418 ? D VAL 418 
1150 1 Y 1 G THR 419 ? D THR 419 
1151 1 Y 1 G ASP 420 ? D ASP 420 
1152 1 Y 1 G VAL 421 ? D VAL 421 
1153 1 Y 1 G ILE 422 ? D ILE 422 
1154 1 Y 1 G ILE 423 ? D ILE 423 
1155 1 Y 1 G LYS 424 ? D LYS 424 
1156 1 Y 1 G ASN 425 ? D ASN 425 
1157 1 Y 1 G ASN 426 ? D ASN 426 
1158 1 Y 1 G LEU 427 ? D LEU 427 
1159 1 Y 1 G LYS 428 ? D LYS 428 
1160 1 Y 1 G ASP 429 ? D ASP 429 
1161 1 Y 1 G CYS 430 ? D CYS 430 
1162 1 Y 1 G GLY 431 ? D GLY 431 
1163 1 Y 1 G LEU 432 ? D LEU 432 
1164 1 Y 1 G PHE 433 ? D PHE 433 
1165 1 Y 1 S ASP 1   ? E ASP 1   
1166 1 Y 1 S GLY 121 A E GLY 122 
1167 1 Y 1 S GLY 121 B E GLY 123 
1168 1 Y 1 S GLY 121 C E GLY 124 
1169 1 Y 1 S GLY 121 D E GLY 125 
1170 1 Y 1 S SER 121 E E SER 126 
1171 1 Y 1 S GLY 121 F E GLY 127 
1172 1 Y 1 S GLY 121 G E GLY 128 
1173 1 Y 1 S GLY 121 H E GLY 129 
1174 1 Y 1 S GLY 121 I E GLY 130 
1175 1 Y 1 S SER 121 J E SER 131 
1176 1 Y 1 S GLY 121 K E GLY 132 
1177 1 Y 1 S GLY 121 L E GLY 133 
1178 1 Y 1 S GLY 121 M E GLY 134 
1179 1 Y 1 S GLY 121 N E GLY 135 
1180 1 Y 1 S LYS 236 ? E LYS 248 
1181 1 Y 1 S ALA 237 ? E ALA 249 
1182 1 Y 1 S ALA 238 ? E ALA 250 
1183 1 Y 1 S ALA 239 ? E ALA 251 
1184 1 Y 1 S ALA 240 ? E ALA 252 
1185 1 Y 1 S SER 241 ? E SER 253 
1186 1 Y 1 S SER 242 ? E SER 254 
1187 1 Y 1 S GLU 243 ? E GLU 255 
1188 1 Y 1 S ASP 244 ? E ASP 256 
1189 1 Y 1 S LEU 245 ? E LEU 257 
1190 1 Y 1 S TYR 246 ? E TYR 258 
1191 1 Y 1 S PHE 247 ? E PHE 259 
1192 1 Y 1 S GLN 248 ? E GLN 260 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
GLN N      N N N 88  
GLN CA     C N S 89  
GLN C      C N N 90  
GLN O      O N N 91  
GLN CB     C N N 92  
GLN CG     C N N 93  
GLN CD     C N N 94  
GLN OE1    O N N 95  
GLN NE2    N N N 96  
GLN OXT    O N N 97  
GLN H      H N N 98  
GLN H2     H N N 99  
GLN HA     H N N 100 
GLN HB2    H N N 101 
GLN HB3    H N N 102 
GLN HG2    H N N 103 
GLN HG3    H N N 104 
GLN HE21   H N N 105 
GLN HE22   H N N 106 
GLN HXT    H N N 107 
GLU N      N N N 108 
GLU CA     C N S 109 
GLU C      C N N 110 
GLU O      O N N 111 
GLU CB     C N N 112 
GLU CG     C N N 113 
GLU CD     C N N 114 
GLU OE1    O N N 115 
GLU OE2    O N N 116 
GLU OXT    O N N 117 
GLU H      H N N 118 
GLU H2     H N N 119 
GLU HA     H N N 120 
GLU HB2    H N N 121 
GLU HB3    H N N 122 
GLU HG2    H N N 123 
GLU HG3    H N N 124 
GLU HE2    H N N 125 
GLU HXT    H N N 126 
GLY N      N N N 127 
GLY CA     C N N 128 
GLY C      C N N 129 
GLY O      O N N 130 
GLY OXT    O N N 131 
GLY H      H N N 132 
GLY H2     H N N 133 
GLY HA2    H N N 134 
GLY HA3    H N N 135 
GLY HXT    H N N 136 
HIS N      N N N 137 
HIS CA     C N S 138 
HIS C      C N N 139 
HIS O      O N N 140 
HIS CB     C N N 141 
HIS CG     C Y N 142 
HIS ND1    N Y N 143 
HIS CD2    C Y N 144 
HIS CE1    C Y N 145 
HIS NE2    N Y N 146 
HIS OXT    O N N 147 
HIS H      H N N 148 
HIS H2     H N N 149 
HIS HA     H N N 150 
HIS HB2    H N N 151 
HIS HB3    H N N 152 
HIS HD1    H N N 153 
HIS HD2    H N N 154 
HIS HE1    H N N 155 
HIS HE2    H N N 156 
HIS HXT    H N N 157 
ILE N      N N N 158 
ILE CA     C N S 159 
ILE C      C N N 160 
ILE O      O N N 161 
ILE CB     C N S 162 
ILE CG1    C N N 163 
ILE CG2    C N N 164 
ILE CD1    C N N 165 
ILE OXT    O N N 166 
ILE H      H N N 167 
ILE H2     H N N 168 
ILE HA     H N N 169 
ILE HB     H N N 170 
ILE HG12   H N N 171 
ILE HG13   H N N 172 
ILE HG21   H N N 173 
ILE HG22   H N N 174 
ILE HG23   H N N 175 
ILE HD11   H N N 176 
ILE HD12   H N N 177 
ILE HD13   H N N 178 
ILE HXT    H N N 179 
LEU N      N N N 180 
LEU CA     C N S 181 
LEU C      C N N 182 
LEU O      O N N 183 
LEU CB     C N N 184 
LEU CG     C N N 185 
LEU CD1    C N N 186 
LEU CD2    C N N 187 
LEU OXT    O N N 188 
LEU H      H N N 189 
LEU H2     H N N 190 
LEU HA     H N N 191 
LEU HB2    H N N 192 
LEU HB3    H N N 193 
LEU HG     H N N 194 
LEU HD11   H N N 195 
LEU HD12   H N N 196 
LEU HD13   H N N 197 
LEU HD21   H N N 198 
LEU HD22   H N N 199 
LEU HD23   H N N 200 
LEU HXT    H N N 201 
LYS N      N N N 202 
LYS CA     C N S 203 
LYS C      C N N 204 
LYS O      O N N 205 
LYS CB     C N N 206 
LYS CG     C N N 207 
LYS CD     C N N 208 
LYS CE     C N N 209 
LYS NZ     N N N 210 
LYS OXT    O N N 211 
LYS H      H N N 212 
LYS H2     H N N 213 
LYS HA     H N N 214 
LYS HB2    H N N 215 
LYS HB3    H N N 216 
LYS HG2    H N N 217 
LYS HG3    H N N 218 
LYS HD2    H N N 219 
LYS HD3    H N N 220 
LYS HE2    H N N 221 
LYS HE3    H N N 222 
LYS HZ1    H N N 223 
LYS HZ2    H N N 224 
LYS HZ3    H N N 225 
LYS HXT    H N N 226 
MET N      N N N 227 
MET CA     C N S 228 
MET C      C N N 229 
MET O      O N N 230 
MET CB     C N N 231 
MET CG     C N N 232 
MET SD     S N N 233 
MET CE     C N N 234 
MET OXT    O N N 235 
MET H      H N N 236 
MET H2     H N N 237 
MET HA     H N N 238 
MET HB2    H N N 239 
MET HB3    H N N 240 
MET HG2    H N N 241 
MET HG3    H N N 242 
MET HE1    H N N 243 
MET HE2    H N N 244 
MET HE3    H N N 245 
MET HXT    H N N 246 
NEC "C5'"  C N N 247 
NEC "O5'"  O N N 248 
NEC "N5'"  N N N 249 
NEC C51    C N N 250 
NEC C52    C N N 251 
NEC "C4'"  C N S 252 
NEC "O4'"  O N N 253 
NEC "C3'"  C N S 254 
NEC "O3'"  O N N 255 
NEC "C2'"  C N R 256 
NEC "O2'"  O N N 257 
NEC "C1'"  C N R 258 
NEC N9     N Y N 259 
NEC C8     C Y N 260 
NEC N7     N Y N 261 
NEC C5     C Y N 262 
NEC C6     C Y N 263 
NEC N6     N N N 264 
NEC N1     N Y N 265 
NEC C2     C Y N 266 
NEC N3     N Y N 267 
NEC C4     C Y N 268 
NEC HN5    H N N 269 
NEC H511   H N N 270 
NEC H512   H N N 271 
NEC H521   H N N 272 
NEC H522   H N N 273 
NEC H523   H N N 274 
NEC "H4'"  H N N 275 
NEC "H3'"  H N N 276 
NEC "HO3'" H N N 277 
NEC "H2'"  H N N 278 
NEC "HO2'" H N N 279 
NEC "H1'"  H N N 280 
NEC H8     H N N 281 
NEC HN61   H N N 282 
NEC HN62   H N N 283 
NEC H2     H N N 284 
PHE N      N N N 285 
PHE CA     C N S 286 
PHE C      C N N 287 
PHE O      O N N 288 
PHE CB     C N N 289 
PHE CG     C Y N 290 
PHE CD1    C Y N 291 
PHE CD2    C Y N 292 
PHE CE1    C Y N 293 
PHE CE2    C Y N 294 
PHE CZ     C Y N 295 
PHE OXT    O N N 296 
PHE H      H N N 297 
PHE H2     H N N 298 
PHE HA     H N N 299 
PHE HB2    H N N 300 
PHE HB3    H N N 301 
PHE HD1    H N N 302 
PHE HD2    H N N 303 
PHE HE1    H N N 304 
PHE HE2    H N N 305 
PHE HZ     H N N 306 
PHE HXT    H N N 307 
PRO N      N N N 308 
PRO CA     C N S 309 
PRO C      C N N 310 
PRO O      O N N 311 
PRO CB     C N N 312 
PRO CG     C N N 313 
PRO CD     C N N 314 
PRO OXT    O N N 315 
PRO H      H N N 316 
PRO HA     H N N 317 
PRO HB2    H N N 318 
PRO HB3    H N N 319 
PRO HG2    H N N 320 
PRO HG3    H N N 321 
PRO HD2    H N N 322 
PRO HD3    H N N 323 
PRO HXT    H N N 324 
SER N      N N N 325 
SER CA     C N S 326 
SER C      C N N 327 
SER O      O N N 328 
SER CB     C N N 329 
SER OG     O N N 330 
SER OXT    O N N 331 
SER H      H N N 332 
SER H2     H N N 333 
SER HA     H N N 334 
SER HB2    H N N 335 
SER HB3    H N N 336 
SER HG     H N N 337 
SER HXT    H N N 338 
THR N      N N N 339 
THR CA     C N S 340 
THR C      C N N 341 
THR O      O N N 342 
THR CB     C N R 343 
THR OG1    O N N 344 
THR CG2    C N N 345 
THR OXT    O N N 346 
THR H      H N N 347 
THR H2     H N N 348 
THR HA     H N N 349 
THR HB     H N N 350 
THR HG1    H N N 351 
THR HG21   H N N 352 
THR HG22   H N N 353 
THR HG23   H N N 354 
THR HXT    H N N 355 
TRP N      N N N 356 
TRP CA     C N S 357 
TRP C      C N N 358 
TRP O      O N N 359 
TRP CB     C N N 360 
TRP CG     C Y N 361 
TRP CD1    C Y N 362 
TRP CD2    C Y N 363 
TRP NE1    N Y N 364 
TRP CE2    C Y N 365 
TRP CE3    C Y N 366 
TRP CZ2    C Y N 367 
TRP CZ3    C Y N 368 
TRP CH2    C Y N 369 
TRP OXT    O N N 370 
TRP H      H N N 371 
TRP H2     H N N 372 
TRP HA     H N N 373 
TRP HB2    H N N 374 
TRP HB3    H N N 375 
TRP HD1    H N N 376 
TRP HE1    H N N 377 
TRP HE3    H N N 378 
TRP HZ2    H N N 379 
TRP HZ3    H N N 380 
TRP HH2    H N N 381 
TRP HXT    H N N 382 
TYR N      N N N 383 
TYR CA     C N S 384 
TYR C      C N N 385 
TYR O      O N N 386 
TYR CB     C N N 387 
TYR CG     C Y N 388 
TYR CD1    C Y N 389 
TYR CD2    C Y N 390 
TYR CE1    C Y N 391 
TYR CE2    C Y N 392 
TYR CZ     C Y N 393 
TYR OH     O N N 394 
TYR OXT    O N N 395 
TYR H      H N N 396 
TYR H2     H N N 397 
TYR HA     H N N 398 
TYR HB2    H N N 399 
TYR HB3    H N N 400 
TYR HD1    H N N 401 
TYR HD2    H N N 402 
TYR HE1    H N N 403 
TYR HE2    H N N 404 
TYR HH     H N N 405 
TYR HXT    H N N 406 
VAL N      N N N 407 
VAL CA     C N S 408 
VAL C      C N N 409 
VAL O      O N N 410 
VAL CB     C N N 411 
VAL CG1    C N N 412 
VAL CG2    C N N 413 
VAL OXT    O N N 414 
VAL H      H N N 415 
VAL H2     H N N 416 
VAL HA     H N N 417 
VAL HB     H N N 418 
VAL HG11   H N N 419 
VAL HG12   H N N 420 
VAL HG13   H N N 421 
VAL HG21   H N N 422 
VAL HG22   H N N 423 
VAL HG23   H N N 424 
VAL HXT    H N N 425 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
GLN N     CA     sing N N 83  
GLN N     H      sing N N 84  
GLN N     H2     sing N N 85  
GLN CA    C      sing N N 86  
GLN CA    CB     sing N N 87  
GLN CA    HA     sing N N 88  
GLN C     O      doub N N 89  
GLN C     OXT    sing N N 90  
GLN CB    CG     sing N N 91  
GLN CB    HB2    sing N N 92  
GLN CB    HB3    sing N N 93  
GLN CG    CD     sing N N 94  
GLN CG    HG2    sing N N 95  
GLN CG    HG3    sing N N 96  
GLN CD    OE1    doub N N 97  
GLN CD    NE2    sing N N 98  
GLN NE2   HE21   sing N N 99  
GLN NE2   HE22   sing N N 100 
GLN OXT   HXT    sing N N 101 
GLU N     CA     sing N N 102 
GLU N     H      sing N N 103 
GLU N     H2     sing N N 104 
GLU CA    C      sing N N 105 
GLU CA    CB     sing N N 106 
GLU CA    HA     sing N N 107 
GLU C     O      doub N N 108 
GLU C     OXT    sing N N 109 
GLU CB    CG     sing N N 110 
GLU CB    HB2    sing N N 111 
GLU CB    HB3    sing N N 112 
GLU CG    CD     sing N N 113 
GLU CG    HG2    sing N N 114 
GLU CG    HG3    sing N N 115 
GLU CD    OE1    doub N N 116 
GLU CD    OE2    sing N N 117 
GLU OE2   HE2    sing N N 118 
GLU OXT   HXT    sing N N 119 
GLY N     CA     sing N N 120 
GLY N     H      sing N N 121 
GLY N     H2     sing N N 122 
GLY CA    C      sing N N 123 
GLY CA    HA2    sing N N 124 
GLY CA    HA3    sing N N 125 
GLY C     O      doub N N 126 
GLY C     OXT    sing N N 127 
GLY OXT   HXT    sing N N 128 
HIS N     CA     sing N N 129 
HIS N     H      sing N N 130 
HIS N     H2     sing N N 131 
HIS CA    C      sing N N 132 
HIS CA    CB     sing N N 133 
HIS CA    HA     sing N N 134 
HIS C     O      doub N N 135 
HIS C     OXT    sing N N 136 
HIS CB    CG     sing N N 137 
HIS CB    HB2    sing N N 138 
HIS CB    HB3    sing N N 139 
HIS CG    ND1    sing Y N 140 
HIS CG    CD2    doub Y N 141 
HIS ND1   CE1    doub Y N 142 
HIS ND1   HD1    sing N N 143 
HIS CD2   NE2    sing Y N 144 
HIS CD2   HD2    sing N N 145 
HIS CE1   NE2    sing Y N 146 
HIS CE1   HE1    sing N N 147 
HIS NE2   HE2    sing N N 148 
HIS OXT   HXT    sing N N 149 
ILE N     CA     sing N N 150 
ILE N     H      sing N N 151 
ILE N     H2     sing N N 152 
ILE CA    C      sing N N 153 
ILE CA    CB     sing N N 154 
ILE CA    HA     sing N N 155 
ILE C     O      doub N N 156 
ILE C     OXT    sing N N 157 
ILE CB    CG1    sing N N 158 
ILE CB    CG2    sing N N 159 
ILE CB    HB     sing N N 160 
ILE CG1   CD1    sing N N 161 
ILE CG1   HG12   sing N N 162 
ILE CG1   HG13   sing N N 163 
ILE CG2   HG21   sing N N 164 
ILE CG2   HG22   sing N N 165 
ILE CG2   HG23   sing N N 166 
ILE CD1   HD11   sing N N 167 
ILE CD1   HD12   sing N N 168 
ILE CD1   HD13   sing N N 169 
ILE OXT   HXT    sing N N 170 
LEU N     CA     sing N N 171 
LEU N     H      sing N N 172 
LEU N     H2     sing N N 173 
LEU CA    C      sing N N 174 
LEU CA    CB     sing N N 175 
LEU CA    HA     sing N N 176 
LEU C     O      doub N N 177 
LEU C     OXT    sing N N 178 
LEU CB    CG     sing N N 179 
LEU CB    HB2    sing N N 180 
LEU CB    HB3    sing N N 181 
LEU CG    CD1    sing N N 182 
LEU CG    CD2    sing N N 183 
LEU CG    HG     sing N N 184 
LEU CD1   HD11   sing N N 185 
LEU CD1   HD12   sing N N 186 
LEU CD1   HD13   sing N N 187 
LEU CD2   HD21   sing N N 188 
LEU CD2   HD22   sing N N 189 
LEU CD2   HD23   sing N N 190 
LEU OXT   HXT    sing N N 191 
LYS N     CA     sing N N 192 
LYS N     H      sing N N 193 
LYS N     H2     sing N N 194 
LYS CA    C      sing N N 195 
LYS CA    CB     sing N N 196 
LYS CA    HA     sing N N 197 
LYS C     O      doub N N 198 
LYS C     OXT    sing N N 199 
LYS CB    CG     sing N N 200 
LYS CB    HB2    sing N N 201 
LYS CB    HB3    sing N N 202 
LYS CG    CD     sing N N 203 
LYS CG    HG2    sing N N 204 
LYS CG    HG3    sing N N 205 
LYS CD    CE     sing N N 206 
LYS CD    HD2    sing N N 207 
LYS CD    HD3    sing N N 208 
LYS CE    NZ     sing N N 209 
LYS CE    HE2    sing N N 210 
LYS CE    HE3    sing N N 211 
LYS NZ    HZ1    sing N N 212 
LYS NZ    HZ2    sing N N 213 
LYS NZ    HZ3    sing N N 214 
LYS OXT   HXT    sing N N 215 
MET N     CA     sing N N 216 
MET N     H      sing N N 217 
MET N     H2     sing N N 218 
MET CA    C      sing N N 219 
MET CA    CB     sing N N 220 
MET CA    HA     sing N N 221 
MET C     O      doub N N 222 
MET C     OXT    sing N N 223 
MET CB    CG     sing N N 224 
MET CB    HB2    sing N N 225 
MET CB    HB3    sing N N 226 
MET CG    SD     sing N N 227 
MET CG    HG2    sing N N 228 
MET CG    HG3    sing N N 229 
MET SD    CE     sing N N 230 
MET CE    HE1    sing N N 231 
MET CE    HE2    sing N N 232 
MET CE    HE3    sing N N 233 
MET OXT   HXT    sing N N 234 
NEC "C5'" "O5'"  doub N N 235 
NEC "C5'" "N5'"  sing N N 236 
NEC "C5'" "C4'"  sing N N 237 
NEC "N5'" C51    sing N N 238 
NEC "N5'" HN5    sing N N 239 
NEC C51   C52    sing N N 240 
NEC C51   H511   sing N N 241 
NEC C51   H512   sing N N 242 
NEC C52   H521   sing N N 243 
NEC C52   H522   sing N N 244 
NEC C52   H523   sing N N 245 
NEC "C4'" "O4'"  sing N N 246 
NEC "C4'" "C3'"  sing N N 247 
NEC "C4'" "H4'"  sing N N 248 
NEC "O4'" "C1'"  sing N N 249 
NEC "C3'" "O3'"  sing N N 250 
NEC "C3'" "C2'"  sing N N 251 
NEC "C3'" "H3'"  sing N N 252 
NEC "O3'" "HO3'" sing N N 253 
NEC "C2'" "O2'"  sing N N 254 
NEC "C2'" "C1'"  sing N N 255 
NEC "C2'" "H2'"  sing N N 256 
NEC "O2'" "HO2'" sing N N 257 
NEC "C1'" N9     sing N N 258 
NEC "C1'" "H1'"  sing N N 259 
NEC N9    C8     sing Y N 260 
NEC N9    C4     sing Y N 261 
NEC C8    N7     doub Y N 262 
NEC C8    H8     sing N N 263 
NEC N7    C5     sing Y N 264 
NEC C5    C6     sing Y N 265 
NEC C5    C4     doub Y N 266 
NEC C6    N6     sing N N 267 
NEC C6    N1     doub Y N 268 
NEC N6    HN61   sing N N 269 
NEC N6    HN62   sing N N 270 
NEC N1    C2     sing Y N 271 
NEC C2    N3     doub Y N 272 
NEC C2    H2     sing N N 273 
NEC N3    C4     sing Y N 274 
PHE N     CA     sing N N 275 
PHE N     H      sing N N 276 
PHE N     H2     sing N N 277 
PHE CA    C      sing N N 278 
PHE CA    CB     sing N N 279 
PHE CA    HA     sing N N 280 
PHE C     O      doub N N 281 
PHE C     OXT    sing N N 282 
PHE CB    CG     sing N N 283 
PHE CB    HB2    sing N N 284 
PHE CB    HB3    sing N N 285 
PHE CG    CD1    doub Y N 286 
PHE CG    CD2    sing Y N 287 
PHE CD1   CE1    sing Y N 288 
PHE CD1   HD1    sing N N 289 
PHE CD2   CE2    doub Y N 290 
PHE CD2   HD2    sing N N 291 
PHE CE1   CZ     doub Y N 292 
PHE CE1   HE1    sing N N 293 
PHE CE2   CZ     sing Y N 294 
PHE CE2   HE2    sing N N 295 
PHE CZ    HZ     sing N N 296 
PHE OXT   HXT    sing N N 297 
PRO N     CA     sing N N 298 
PRO N     CD     sing N N 299 
PRO N     H      sing N N 300 
PRO CA    C      sing N N 301 
PRO CA    CB     sing N N 302 
PRO CA    HA     sing N N 303 
PRO C     O      doub N N 304 
PRO C     OXT    sing N N 305 
PRO CB    CG     sing N N 306 
PRO CB    HB2    sing N N 307 
PRO CB    HB3    sing N N 308 
PRO CG    CD     sing N N 309 
PRO CG    HG2    sing N N 310 
PRO CG    HG3    sing N N 311 
PRO CD    HD2    sing N N 312 
PRO CD    HD3    sing N N 313 
PRO OXT   HXT    sing N N 314 
SER N     CA     sing N N 315 
SER N     H      sing N N 316 
SER N     H2     sing N N 317 
SER CA    C      sing N N 318 
SER CA    CB     sing N N 319 
SER CA    HA     sing N N 320 
SER C     O      doub N N 321 
SER C     OXT    sing N N 322 
SER CB    OG     sing N N 323 
SER CB    HB2    sing N N 324 
SER CB    HB3    sing N N 325 
SER OG    HG     sing N N 326 
SER OXT   HXT    sing N N 327 
THR N     CA     sing N N 328 
THR N     H      sing N N 329 
THR N     H2     sing N N 330 
THR CA    C      sing N N 331 
THR CA    CB     sing N N 332 
THR CA    HA     sing N N 333 
THR C     O      doub N N 334 
THR C     OXT    sing N N 335 
THR CB    OG1    sing N N 336 
THR CB    CG2    sing N N 337 
THR CB    HB     sing N N 338 
THR OG1   HG1    sing N N 339 
THR CG2   HG21   sing N N 340 
THR CG2   HG22   sing N N 341 
THR CG2   HG23   sing N N 342 
THR OXT   HXT    sing N N 343 
TRP N     CA     sing N N 344 
TRP N     H      sing N N 345 
TRP N     H2     sing N N 346 
TRP CA    C      sing N N 347 
TRP CA    CB     sing N N 348 
TRP CA    HA     sing N N 349 
TRP C     O      doub N N 350 
TRP C     OXT    sing N N 351 
TRP CB    CG     sing N N 352 
TRP CB    HB2    sing N N 353 
TRP CB    HB3    sing N N 354 
TRP CG    CD1    doub Y N 355 
TRP CG    CD2    sing Y N 356 
TRP CD1   NE1    sing Y N 357 
TRP CD1   HD1    sing N N 358 
TRP CD2   CE2    doub Y N 359 
TRP CD2   CE3    sing Y N 360 
TRP NE1   CE2    sing Y N 361 
TRP NE1   HE1    sing N N 362 
TRP CE2   CZ2    sing Y N 363 
TRP CE3   CZ3    doub Y N 364 
TRP CE3   HE3    sing N N 365 
TRP CZ2   CH2    doub Y N 366 
TRP CZ2   HZ2    sing N N 367 
TRP CZ3   CH2    sing Y N 368 
TRP CZ3   HZ3    sing N N 369 
TRP CH2   HH2    sing N N 370 
TRP OXT   HXT    sing N N 371 
TYR N     CA     sing N N 372 
TYR N     H      sing N N 373 
TYR N     H2     sing N N 374 
TYR CA    C      sing N N 375 
TYR CA    CB     sing N N 376 
TYR CA    HA     sing N N 377 
TYR C     O      doub N N 378 
TYR C     OXT    sing N N 379 
TYR CB    CG     sing N N 380 
TYR CB    HB2    sing N N 381 
TYR CB    HB3    sing N N 382 
TYR CG    CD1    doub Y N 383 
TYR CG    CD2    sing Y N 384 
TYR CD1   CE1    sing Y N 385 
TYR CD1   HD1    sing N N 386 
TYR CD2   CE2    doub Y N 387 
TYR CD2   HD2    sing N N 388 
TYR CE1   CZ     doub Y N 389 
TYR CE1   HE1    sing N N 390 
TYR CE2   CZ     sing Y N 391 
TYR CE2   HE2    sing N N 392 
TYR CZ    OH     sing N N 393 
TYR OH    HH     sing N N 394 
TYR OXT   HXT    sing N N 395 
VAL N     CA     sing N N 396 
VAL N     H      sing N N 397 
VAL N     H2     sing N N 398 
VAL CA    C      sing N N 399 
VAL CA    CB     sing N N 400 
VAL CA    HA     sing N N 401 
VAL C     O      doub N N 402 
VAL C     OXT    sing N N 403 
VAL CB    CG1    sing N N 404 
VAL CB    CG2    sing N N 405 
VAL CB    HB     sing N N 406 
VAL CG1   HG11   sing N N 407 
VAL CG1   HG12   sing N N 408 
VAL CG1   HG13   sing N N 409 
VAL CG2   HG21   sing N N 410 
VAL CG2   HG22   sing N N 411 
VAL CG2   HG23   sing N N 412 
VAL OXT   HXT    sing N N 413 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-02-27 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8YH0 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-06 
_em_admin.title              'A3R-Gi complex bound to NECA' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9940 
_em_entity_assembly_naturalsource.organism             'Ovis aries' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?         ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?         ? 
MASKING                    ? 3  ? ? ? ?         ? 
'CTF CORRECTION'           ? 4  1 ? ? ?         ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ? 
'MODEL FITTING'            ? 7  ? ? ? ?         ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ?         ? 
OTHER                      ? 9  ? ? ? ?         ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? cryoSPARC ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?         ? 
CLASSIFICATION             ? 12 1 ? ? ?         ? 
RECONSTRUCTION             ? 13 1 ? ? ?         ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Japan Society for the Promotion of Science (JSPS)' 
_pdbx_audit_support.country                Japan 
_pdbx_audit_support.grant_number           21H05037 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8YH0 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . SER A 1 34  ? 83.901  118.636 151.185 1.00 54.89  ? 9   SER R N     1 
ATOM   2    C CA    . SER A 1 34  ? 84.212  119.975 151.762 1.00 54.89  ? 9   SER R CA    1 
ATOM   3    C C     . SER A 1 34  ? 84.613  120.957 150.666 1.00 54.89  ? 9   SER R C     1 
ATOM   4    O O     . SER A 1 34  ? 84.840  120.566 149.522 1.00 54.89  ? 9   SER R O     1 
ATOM   5    C CB    . SER A 1 34  ? 85.328  119.863 152.802 1.00 54.89  ? 9   SER R CB    1 
ATOM   6    O OG    . SER A 1 34  ? 86.496  119.295 152.236 1.00 54.89  ? 9   SER R OG    1 
ATOM   7    N N     . TRP A 1 35  ? 84.696  122.239 151.026 1.00 56.86  ? 10  TRP R N     1 
ATOM   8    C CA    . TRP A 1 35  ? 85.109  123.254 150.061 1.00 56.86  ? 10  TRP R CA    1 
ATOM   9    C C     . TRP A 1 35  ? 86.540  123.011 149.598 1.00 56.86  ? 10  TRP R C     1 
ATOM   10   O O     . TRP A 1 35  ? 86.856  123.155 148.410 1.00 56.86  ? 10  TRP R O     1 
ATOM   11   C CB    . TRP A 1 35  ? 84.977  124.646 150.680 1.00 56.86  ? 10  TRP R CB    1 
ATOM   12   C CG    . TRP A 1 35  ? 83.561  125.115 150.831 1.00 56.86  ? 10  TRP R CG    1 
ATOM   13   C CD1   . TRP A 1 35  ? 82.427  124.406 150.561 1.00 56.86  ? 10  TRP R CD1   1 
ATOM   14   C CD2   . TRP A 1 35  ? 83.129  126.401 151.293 1.00 56.86  ? 10  TRP R CD2   1 
ATOM   15   N NE1   . TRP A 1 35  ? 81.316  125.171 150.824 1.00 56.86  ? 10  TRP R NE1   1 
ATOM   16   C CE2   . TRP A 1 35  ? 81.721  126.400 151.275 1.00 56.86  ? 10  TRP R CE2   1 
ATOM   17   C CE3   . TRP A 1 35  ? 83.798  127.552 151.719 1.00 56.86  ? 10  TRP R CE3   1 
ATOM   18   C CZ2   . TRP A 1 35  ? 80.969  127.505 151.667 1.00 56.86  ? 10  TRP R CZ2   1 
ATOM   19   C CZ3   . TRP A 1 35  ? 83.050  128.649 152.108 1.00 56.86  ? 10  TRP R CZ3   1 
ATOM   20   C CH2   . TRP A 1 35  ? 81.650  128.617 152.079 1.00 56.86  ? 10  TRP R CH2   1 
ATOM   21   N N     . THR A 1 36  ? 87.421  122.641 150.529 1.00 51.07  ? 11  THR R N     1 
ATOM   22   C CA    . THR A 1 36  ? 88.821  122.423 150.186 1.00 51.07  ? 11  THR R CA    1 
ATOM   23   C C     . THR A 1 36  ? 88.964  121.307 149.160 1.00 51.07  ? 11  THR R C     1 
ATOM   24   O O     . THR A 1 36  ? 89.736  121.422 148.203 1.00 51.07  ? 11  THR R O     1 
ATOM   25   C CB    . THR A 1 36  ? 89.626  122.096 151.445 1.00 51.07  ? 11  THR R CB    1 
ATOM   26   O OG1   . THR A 1 36  ? 89.070  120.941 152.085 1.00 51.07  ? 11  THR R OG1   1 
ATOM   27   C CG2   . THR A 1 36  ? 89.604  123.269 152.415 1.00 51.07  ? 11  THR R CG2   1 
ATOM   28   N N     . SER A 1 37  ? 88.226  120.212 149.348 1.00 49.30  ? 12  SER R N     1 
ATOM   29   C CA    . SER A 1 37  ? 88.313  119.089 148.422 1.00 49.30  ? 12  SER R CA    1 
ATOM   30   C C     . SER A 1 37  ? 87.879  119.502 147.020 1.00 49.30  ? 12  SER R C     1 
ATOM   31   O O     . SER A 1 37  ? 88.535  119.172 146.026 1.00 49.30  ? 12  SER R O     1 
ATOM   32   C CB    . SER A 1 37  ? 87.457  117.928 148.934 1.00 49.30  ? 12  SER R CB    1 
ATOM   33   O OG    . SER A 1 37  ? 88.061  117.304 150.053 1.00 49.30  ? 12  SER R OG    1 
ATOM   34   N N     . VAL A 1 38  ? 86.765  120.232 146.926 1.00 50.40  ? 13  VAL R N     1 
ATOM   35   C CA    . VAL A 1 38  ? 86.258  120.652 145.621 1.00 50.40  ? 13  VAL R CA    1 
ATOM   36   C C     . VAL A 1 38  ? 87.255  121.583 144.944 1.00 50.40  ? 13  VAL R C     1 
ATOM   37   O O     . VAL A 1 38  ? 87.546  121.451 143.747 1.00 50.40  ? 13  VAL R O     1 
ATOM   38   C CB    . VAL A 1 38  ? 84.880  121.320 145.773 1.00 50.40  ? 13  VAL R CB    1 
ATOM   39   C CG1   . VAL A 1 38  ? 84.497  122.052 144.495 1.00 50.40  ? 13  VAL R CG1   1 
ATOM   40   C CG2   . VAL A 1 38  ? 83.828  120.285 146.139 1.00 50.40  ? 13  VAL R CG2   1 
ATOM   41   N N     . THR A 1 39  ? 87.787  122.544 145.700 1.00 47.07  ? 14  THR R N     1 
ATOM   42   C CA    . THR A 1 39  ? 88.754  123.482 145.140 1.00 47.07  ? 14  THR R CA    1 
ATOM   43   C C     . THR A 1 39  ? 89.993  122.746 144.645 1.00 47.07  ? 14  THR R C     1 
ATOM   44   O O     . THR A 1 39  ? 90.507  123.019 143.553 1.00 47.07  ? 14  THR R O     1 
ATOM   45   C CB    . THR A 1 39  ? 89.131  124.530 146.190 1.00 47.07  ? 14  THR R CB    1 
ATOM   46   O OG1   . THR A 1 39  ? 87.972  125.291 146.550 1.00 47.07  ? 14  THR R OG1   1 
ATOM   47   C CG2   . THR A 1 39  ? 90.205  125.467 145.656 1.00 47.07  ? 14  THR R CG2   1 
ATOM   48   N N     . TYR A 1 40  ? 90.485  121.801 145.447 1.00 41.97  ? 15  TYR R N     1 
ATOM   49   C CA    . TYR A 1 40  ? 91.662  121.030 145.072 1.00 41.97  ? 15  TYR R CA    1 
ATOM   50   C C     . TYR A 1 40  ? 91.411  120.241 143.795 1.00 41.97  ? 15  TYR R C     1 
ATOM   51   O O     . TYR A 1 40  ? 92.242  120.228 142.884 1.00 41.97  ? 15  TYR R O     1 
ATOM   52   C CB    . TYR A 1 40  ? 92.046  120.098 146.223 1.00 41.97  ? 15  TYR R CB    1 
ATOM   53   C CG    . TYR A 1 40  ? 93.024  119.010 145.845 1.00 41.97  ? 15  TYR R CG    1 
ATOM   54   C CD1   . TYR A 1 40  ? 94.355  119.303 145.584 1.00 41.97  ? 15  TYR R CD1   1 
ATOM   55   C CD2   . TYR A 1 40  ? 92.615  117.687 145.757 1.00 41.97  ? 15  TYR R CD2   1 
ATOM   56   C CE1   . TYR A 1 40  ? 95.249  118.308 145.243 1.00 41.97  ? 15  TYR R CE1   1 
ATOM   57   C CE2   . TYR A 1 40  ? 93.501  116.687 145.416 1.00 41.97  ? 15  TYR R CE2   1 
ATOM   58   C CZ    . TYR A 1 40  ? 94.816  117.002 145.161 1.00 41.97  ? 15  TYR R CZ    1 
ATOM   59   O OH    . TYR A 1 40  ? 95.701  116.005 144.821 1.00 41.97  ? 15  TYR R OH    1 
ATOM   60   N N     . ILE A 1 41  ? 90.252  119.585 143.708 1.00 44.45  ? 16  ILE R N     1 
ATOM   61   C CA    . ILE A 1 41  ? 89.938  118.786 142.525 1.00 44.45  ? 16  ILE R CA    1 
ATOM   62   C C     . ILE A 1 41  ? 89.866  119.675 141.290 1.00 44.45  ? 16  ILE R C     1 
ATOM   63   O O     . ILE A 1 41  ? 90.399  119.338 140.226 1.00 44.45  ? 16  ILE R O     1 
ATOM   64   C CB    . ILE A 1 41  ? 88.628  118.005 142.736 1.00 44.45  ? 16  ILE R CB    1 
ATOM   65   C CG1   . ILE A 1 41  ? 88.818  116.943 143.822 1.00 44.45  ? 16  ILE R CG1   1 
ATOM   66   C CG2   . ILE A 1 41  ? 88.175  117.366 141.430 1.00 44.45  ? 16  ILE R CG2   1 
ATOM   67   C CD1   . ILE A 1 41  ? 87.526  116.309 144.298 1.00 44.45  ? 16  ILE R CD1   1 
ATOM   68   N N     . THR A 1 42  ? 89.201  120.826 141.413 1.00 44.65  ? 17  THR R N     1 
ATOM   69   C CA    . THR A 1 42  ? 89.053  121.725 140.273 1.00 44.65  ? 17  THR R CA    1 
ATOM   70   C C     . THR A 1 42  ? 90.410  122.234 139.795 1.00 44.65  ? 17  THR R C     1 
ATOM   71   O O     . THR A 1 42  ? 90.721  122.202 138.596 1.00 44.65  ? 17  THR R O     1 
ATOM   72   C CB    . THR A 1 42  ? 88.141  122.894 140.649 1.00 44.65  ? 17  THR R CB    1 
ATOM   73   O OG1   . THR A 1 42  ? 86.838  122.399 140.984 1.00 44.65  ? 17  THR R OG1   1 
ATOM   74   C CG2   . THR A 1 42  ? 88.024  123.879 139.493 1.00 44.65  ? 17  THR R CG2   1 
ATOM   75   N N     . VAL A 1 43  ? 91.235  122.713 140.728 1.00 41.15  ? 18  VAL R N     1 
ATOM   76   C CA    . VAL A 1 43  ? 92.542  123.242 140.349 1.00 41.15  ? 18  VAL R CA    1 
ATOM   77   C C     . VAL A 1 43  ? 93.395  122.137 139.739 1.00 41.15  ? 18  VAL R C     1 
ATOM   78   O O     . VAL A 1 43  ? 94.103  122.349 138.749 1.00 41.15  ? 18  VAL R O     1 
ATOM   79   C CB    . VAL A 1 43  ? 93.238  123.889 141.559 1.00 41.15  ? 18  VAL R CB    1 
ATOM   80   C CG1   . VAL A 1 43  ? 94.631  124.364 141.174 1.00 41.15  ? 18  VAL R CG1   1 
ATOM   81   C CG2   . VAL A 1 43  ? 92.411  125.050 142.092 1.00 41.15  ? 18  VAL R CG2   1 
ATOM   82   N N     . GLU A 1 44  ? 93.334  120.938 140.321 1.00 41.83  ? 19  GLU R N     1 
ATOM   83   C CA    . GLU A 1 44  ? 94.115  119.814 139.823 1.00 41.83  ? 19  GLU R CA    1 
ATOM   84   C C     . GLU A 1 44  ? 93.726  119.470 138.392 1.00 41.83  ? 19  GLU R C     1 
ATOM   85   O O     . GLU A 1 44  ? 94.588  119.288 137.525 1.00 41.83  ? 19  GLU R O     1 
ATOM   86   C CB    . GLU A 1 44  ? 93.907  118.613 140.749 1.00 41.83  ? 19  GLU R CB    1 
ATOM   87   C CG    . GLU A 1 44  ? 94.663  117.354 140.360 1.00 41.83  ? 19  GLU R CG    1 
ATOM   88   C CD    . GLU A 1 44  ? 96.012  117.252 141.038 1.00 41.83  ? 19  GLU R CD    1 
ATOM   89   O OE1   . GLU A 1 44  ? 96.466  118.252 141.631 1.00 41.83  ? 19  GLU R OE1   1 
ATOM   90   O OE2   . GLU A 1 44  ? 96.611  116.161 140.990 1.00 41.83  ? 19  GLU R OE2   1 
ATOM   91   N N     . ILE A 1 45  ? 92.422  119.369 138.124 1.00 44.06  ? 20  ILE R N     1 
ATOM   92   C CA    . ILE A 1 45  ? 91.980  118.988 136.786 1.00 44.06  ? 20  ILE R CA    1 
ATOM   93   C C     . ILE A 1 45  ? 92.357  120.068 135.778 1.00 44.06  ? 20  ILE R C     1 
ATOM   94   O O     . ILE A 1 45  ? 92.830  119.771 134.674 1.00 44.06  ? 20  ILE R O     1 
ATOM   95   C CB    . ILE A 1 45  ? 90.468  118.687 136.772 1.00 44.06  ? 20  ILE R CB    1 
ATOM   96   C CG1   . ILE A 1 45  ? 90.047  118.163 135.396 1.00 44.06  ? 20  ILE R CG1   1 
ATOM   97   C CG2   . ILE A 1 45  ? 89.651  119.912 137.151 1.00 44.06  ? 20  ILE R CG2   1 
ATOM   98   C CD1   . ILE A 1 45  ? 88.638  117.610 135.355 1.00 44.06  ? 20  ILE R CD1   1 
ATOM   99   N N     . LEU A 1 46  ? 92.169  121.339 136.145 1.00 43.65  ? 21  LEU R N     1 
ATOM   100  C CA    . LEU A 1 46  ? 92.534  122.418 135.232 1.00 43.65  ? 21  LEU R CA    1 
ATOM   101  C C     . LEU A 1 46  ? 94.028  122.394 134.925 1.00 43.65  ? 21  LEU R C     1 
ATOM   102  O O     . LEU A 1 46  ? 94.442  122.526 133.766 1.00 43.65  ? 21  LEU R O     1 
ATOM   103  C CB    . LEU A 1 46  ? 92.126  123.767 135.825 1.00 43.65  ? 21  LEU R CB    1 
ATOM   104  C CG    . LEU A 1 46  ? 90.621  124.030 135.883 1.00 43.65  ? 21  LEU R CG    1 
ATOM   105  C CD1   . LEU A 1 46  ? 90.308  125.147 136.865 1.00 43.65  ? 21  LEU R CD1   1 
ATOM   106  C CD2   . LEU A 1 46  ? 90.083  124.364 134.501 1.00 43.65  ? 21  LEU R CD2   1 
ATOM   107  N N     . ILE A 1 47  ? 94.856  122.212 135.957 1.00 39.19  ? 22  ILE R N     1 
ATOM   108  C CA    . ILE A 1 47  ? 96.303  122.217 135.766 1.00 39.19  ? 22  ILE R CA    1 
ATOM   109  C C     . ILE A 1 47  ? 96.728  121.040 134.898 1.00 39.19  ? 22  ILE R C     1 
ATOM   110  O O     . ILE A 1 47  ? 97.587  121.172 134.018 1.00 39.19  ? 22  ILE R O     1 
ATOM   111  C CB    . ILE A 1 47  ? 97.016  122.205 137.130 1.00 39.19  ? 22  ILE R CB    1 
ATOM   112  C CG1   . ILE A 1 47  ? 96.938  123.592 137.772 1.00 39.19  ? 22  ILE R CG1   1 
ATOM   113  C CG2   . ILE A 1 47  ? 98.460  121.765 136.970 1.00 39.19  ? 22  ILE R CG2   1 
ATOM   114  C CD1   . ILE A 1 47  ? 97.410  123.636 139.210 1.00 39.19  ? 22  ILE R CD1   1 
ATOM   115  N N     . GLY A 1 48  ? 96.148  119.864 135.143 1.00 41.06  ? 23  GLY R N     1 
ATOM   116  C CA    . GLY A 1 48  ? 96.492  118.705 134.336 1.00 41.06  ? 23  GLY R CA    1 
ATOM   117  C C     . GLY A 1 48  ? 96.100  118.880 132.882 1.00 41.06  ? 23  GLY R C     1 
ATOM   118  O O     . GLY A 1 48  ? 96.848  118.507 131.972 1.00 41.06  ? 23  GLY R O     1 
ATOM   119  N N     . LEU A 1 49  ? 94.916  119.447 132.641 1.00 44.24  ? 24  LEU R N     1 
ATOM   120  C CA    . LEU A 1 49  ? 94.502  119.720 131.269 1.00 44.24  ? 24  LEU R CA    1 
ATOM   121  C C     . LEU A 1 49  ? 95.461  120.694 130.599 1.00 44.24  ? 24  LEU R C     1 
ATOM   122  O O     . LEU A 1 49  ? 95.833  120.516 129.432 1.00 44.24  ? 24  LEU R O     1 
ATOM   123  C CB    . LEU A 1 49  ? 93.073  120.266 131.248 1.00 44.24  ? 24  LEU R CB    1 
ATOM   124  C CG    . LEU A 1 49  ? 91.948  119.245 131.044 1.00 44.24  ? 24  LEU R CG    1 
ATOM   125  C CD1   . LEU A 1 49  ? 92.036  118.610 129.663 1.00 44.24  ? 24  LEU R CD1   1 
ATOM   126  C CD2   . LEU A 1 49  ? 91.964  118.174 132.126 1.00 44.24  ? 24  LEU R CD2   1 
ATOM   127  N N     . CYS A 1 50  ? 95.875  121.735 131.325 1.00 43.70  ? 25  CYS R N     1 
ATOM   128  C CA    . CYS A 1 50  ? 96.829  122.689 130.767 1.00 43.70  ? 25  CYS R CA    1 
ATOM   129  C C     . CYS A 1 50  ? 98.147  122.004 130.420 1.00 43.70  ? 25  CYS R C     1 
ATOM   130  O O     . CYS A 1 50  ? 98.732  122.254 129.359 1.00 43.70  ? 25  CYS R O     1 
ATOM   131  C CB    . CYS A 1 50  ? 97.060  123.834 131.753 1.00 43.70  ? 25  CYS R CB    1 
ATOM   132  S SG    . CYS A 1 50  ? 95.575  124.785 132.152 1.00 43.70  ? 25  CYS R SG    1 
ATOM   133  N N     . ALA A 1 51  ? 98.630  121.137 131.312 1.00 39.74  ? 26  ALA R N     1 
ATOM   134  C CA    . ALA A 1 51  ? 99.876  120.420 131.060 1.00 39.74  ? 26  ALA R CA    1 
ATOM   135  C C     . ALA A 1 51  ? 99.762  119.564 129.806 1.00 39.74  ? 26  ALA R C     1 
ATOM   136  O O     . ALA A 1 51  ? 100.654 119.558 128.948 1.00 39.74  ? 26  ALA R O     1 
ATOM   137  C CB    . ALA A 1 51  ? 100.232 119.548 132.266 1.00 39.74  ? 26  ALA R CB    1 
ATOM   138  N N     . ILE A 1 52  ? 98.655  118.827 129.691 1.00 40.46  ? 27  ILE R N     1 
ATOM   139  C CA    . ILE A 1 52  ? 98.457  117.957 128.534 1.00 40.46  ? 27  ILE R CA    1 
ATOM   140  C C     . ILE A 1 52  ? 98.432  118.784 127.257 1.00 40.46  ? 27  ILE R C     1 
ATOM   141  O O     . ILE A 1 52  ? 99.066  118.435 126.256 1.00 40.46  ? 27  ILE R O     1 
ATOM   142  C CB    . ILE A 1 52  ? 97.166  117.135 128.695 1.00 40.46  ? 27  ILE R CB    1 
ATOM   143  C CG1   . ILE A 1 52  ? 97.331  116.095 129.803 1.00 40.46  ? 27  ILE R CG1   1 
ATOM   144  C CG2   . ILE A 1 52  ? 96.800  116.455 127.385 1.00 40.46  ? 27  ILE R CG2   1 
ATOM   145  C CD1   . ILE A 1 52  ? 96.019  115.621 130.383 1.00 40.46  ? 27  ILE R CD1   1 
ATOM   146  N N     . VAL A 1 53  ? 97.700  119.900 127.276 1.00 41.61  ? 28  VAL R N     1 
ATOM   147  C CA    . VAL A 1 53  ? 97.580  120.728 126.077 1.00 41.61  ? 28  VAL R CA    1 
ATOM   148  C C     . VAL A 1 53  ? 98.944  121.272 125.673 1.00 41.61  ? 28  VAL R C     1 
ATOM   149  O O     . VAL A 1 53  ? 99.333  121.223 124.499 1.00 41.61  ? 28  VAL R O     1 
ATOM   150  C CB    . VAL A 1 53  ? 96.565  121.862 126.310 1.00 41.61  ? 28  VAL R CB    1 
ATOM   151  C CG1   . VAL A 1 53  ? 96.707  122.937 125.242 1.00 41.61  ? 28  VAL R CG1   1 
ATOM   152  C CG2   . VAL A 1 53  ? 95.149  121.309 126.330 1.00 41.61  ? 28  VAL R CG2   1 
ATOM   153  N N     . GLY A 1 54  ? 99.694  121.796 126.644 1.00 39.42  ? 29  GLY R N     1 
ATOM   154  C CA    . GLY A 1 54  ? 100.994 122.365 126.327 1.00 39.42  ? 29  GLY R CA    1 
ATOM   155  C C     . GLY A 1 54  ? 101.957 121.335 125.769 1.00 39.42  ? 29  GLY R C     1 
ATOM   156  O O     . GLY A 1 54  ? 102.641 121.577 124.770 1.00 39.42  ? 29  GLY R O     1 
ATOM   157  N N     . ASN A 1 55  ? 102.017 120.163 126.402 1.00 37.56  ? 30  ASN R N     1 
ATOM   158  C CA    . ASN A 1 55  ? 102.946 119.139 125.940 1.00 37.56  ? 30  ASN R CA    1 
ATOM   159  C C     . ASN A 1 55  ? 102.533 118.591 124.579 1.00 37.56  ? 30  ASN R C     1 
ATOM   160  O O     . ASN A 1 55  ? 103.390 118.287 123.740 1.00 37.56  ? 30  ASN R O     1 
ATOM   161  C CB    . ASN A 1 55  ? 103.039 118.022 126.973 1.00 37.56  ? 30  ASN R CB    1 
ATOM   162  C CG    . ASN A 1 55  ? 103.493 118.523 128.328 1.00 37.56  ? 30  ASN R CG    1 
ATOM   163  O OD1   . ASN A 1 55  ? 104.609 119.018 128.477 1.00 37.56  ? 30  ASN R OD1   1 
ATOM   164  N ND2   . ASN A 1 55  ? 102.623 118.406 129.323 1.00 37.56  ? 30  ASN R ND2   1 
ATOM   165  N N     . VAL A 1 56  ? 101.227 118.465 124.334 1.00 39.67  ? 31  VAL R N     1 
ATOM   166  C CA    . VAL A 1 56  ? 100.764 118.014 123.026 1.00 39.67  ? 31  VAL R CA    1 
ATOM   167  C C     . VAL A 1 56  ? 101.138 119.030 121.958 1.00 39.67  ? 31  VAL R C     1 
ATOM   168  O O     . VAL A 1 56  ? 101.549 118.665 120.851 1.00 39.67  ? 31  VAL R O     1 
ATOM   169  C CB    . VAL A 1 56  ? 99.246  117.753 123.057 1.00 39.67  ? 31  VAL R CB    1 
ATOM   170  C CG1   . VAL A 1 56  ? 98.684  117.699 121.643 1.00 39.67  ? 31  VAL R CG1   1 
ATOM   171  C CG2   . VAL A 1 56  ? 98.948  116.462 123.802 1.00 39.67  ? 31  VAL R CG2   1 
ATOM   172  N N     . LEU A 1 57  ? 100.996 120.321 122.267 1.00 41.63  ? 32  LEU R N     1 
ATOM   173  C CA    . LEU A 1 57  ? 101.412 121.351 121.320 1.00 41.63  ? 32  LEU R CA    1 
ATOM   174  C C     . LEU A 1 57  ? 102.907 121.260 121.043 1.00 41.63  ? 32  LEU R C     1 
ATOM   175  O O     . LEU A 1 57  ? 103.349 121.404 119.897 1.00 41.63  ? 32  LEU R O     1 
ATOM   176  C CB    . LEU A 1 57  ? 101.047 122.735 121.857 1.00 41.63  ? 32  LEU R CB    1 
ATOM   177  C CG    . LEU A 1 57  ? 99.558  123.087 121.862 1.00 41.63  ? 32  LEU R CG    1 
ATOM   178  C CD1   . LEU A 1 57  ? 99.326  124.404 122.586 1.00 41.63  ? 32  LEU R CD1   1 
ATOM   179  C CD2   . LEU A 1 57  ? 99.013  123.153 120.444 1.00 41.63  ? 32  LEU R CD2   1 
ATOM   180  N N     . VAL A 1 58  ? 103.704 121.022 122.087 1.00 39.24  ? 33  VAL R N     1 
ATOM   181  C CA    . VAL A 1 58  ? 105.152 120.902 121.907 1.00 39.24  ? 33  VAL R CA    1 
ATOM   182  C C     . VAL A 1 58  ? 105.470 119.737 120.976 1.00 39.24  ? 33  VAL R C     1 
ATOM   183  O O     . VAL A 1 58  ? 106.288 119.852 120.054 1.00 39.24  ? 33  VAL R O     1 
ATOM   184  C CB    . VAL A 1 58  ? 105.854 120.739 123.266 1.00 39.24  ? 33  VAL R CB    1 
ATOM   185  C CG1   . VAL A 1 58  ? 107.248 120.152 123.086 1.00 39.24  ? 33  VAL R CG1   1 
ATOM   186  C CG2   . VAL A 1 58  ? 105.924 122.073 123.990 1.00 39.24  ? 33  VAL R CG2   1 
ATOM   187  N N     . ILE A 1 59  ? 104.827 118.592 121.213 1.00 39.79  ? 34  ILE R N     1 
ATOM   188  C CA    . ILE A 1 59  ? 105.078 117.412 120.387 1.00 39.79  ? 34  ILE R CA    1 
ATOM   189  C C     . ILE A 1 59  ? 104.669 117.680 118.944 1.00 39.79  ? 34  ILE R C     1 
ATOM   190  O O     . ILE A 1 59  ? 105.379 117.316 117.998 1.00 39.79  ? 34  ILE R O     1 
ATOM   191  C CB    . ILE A 1 59  ? 104.343 116.186 120.960 1.00 39.79  ? 34  ILE R CB    1 
ATOM   192  C CG1   . ILE A 1 59  ? 104.933 115.779 122.315 1.00 39.79  ? 34  ILE R CG1   1 
ATOM   193  C CG2   . ILE A 1 59  ? 104.404 115.023 119.980 1.00 39.79  ? 34  ILE R CG2   1 
ATOM   194  C CD1   . ILE A 1 59  ? 106.423 115.497 122.291 1.00 39.79  ? 34  ILE R CD1   1 
ATOM   195  N N     . TRP A 1 60  ? 103.504 118.301 118.755 1.00 46.83  ? 35  TRP R N     1 
ATOM   196  C CA    . TRP A 1 60  ? 103.032 118.629 117.416 1.00 46.83  ? 35  TRP R CA    1 
ATOM   197  C C     . TRP A 1 60  ? 104.047 119.504 116.692 1.00 46.83  ? 35  TRP R C     1 
ATOM   198  O O     . TRP A 1 60  ? 104.424 119.235 115.544 1.00 46.83  ? 35  TRP R O     1 
ATOM   199  C CB    . TRP A 1 60  ? 101.677 119.333 117.519 1.00 46.83  ? 35  TRP R CB    1 
ATOM   200  C CG    . TRP A 1 60  ? 101.023 119.632 116.206 1.00 46.83  ? 35  TRP R CG    1 
ATOM   201  C CD1   . TRP A 1 60  ? 100.836 120.861 115.646 1.00 46.83  ? 35  TRP R CD1   1 
ATOM   202  C CD2   . TRP A 1 60  ? 100.447 118.685 115.299 1.00 46.83  ? 35  TRP R CD2   1 
ATOM   203  N NE1   . TRP A 1 60  ? 100.188 120.739 114.441 1.00 46.83  ? 35  TRP R NE1   1 
ATOM   204  C CE2   . TRP A 1 60  ? 99.936  119.413 114.206 1.00 46.83  ? 35  TRP R CE2   1 
ATOM   205  C CE3   . TRP A 1 60  ? 100.316 117.294 115.302 1.00 46.83  ? 35  TRP R CE3   1 
ATOM   206  C CZ2   . TRP A 1 60  ? 99.309  118.796 113.126 1.00 46.83  ? 35  TRP R CZ2   1 
ATOM   207  C CZ3   . TRP A 1 60  ? 99.693  116.683 114.229 1.00 46.83  ? 35  TRP R CZ3   1 
ATOM   208  C CH2   . TRP A 1 60  ? 99.197  117.434 113.156 1.00 46.83  ? 35  TRP R CH2   1 
ATOM   209  N N     . VAL A 1 61  ? 104.520 120.551 117.370 1.00 44.61  ? 36  VAL R N     1 
ATOM   210  C CA    . VAL A 1 61  ? 105.476 121.470 116.758 1.00 44.61  ? 36  VAL R CA    1 
ATOM   211  C C     . VAL A 1 61  ? 106.752 120.731 116.380 1.00 44.61  ? 36  VAL R C     1 
ATOM   212  O O     . VAL A 1 61  ? 107.283 120.891 115.275 1.00 44.61  ? 36  VAL R O     1 
ATOM   213  C CB    . VAL A 1 61  ? 105.767 122.646 117.707 1.00 44.61  ? 36  VAL R CB    1 
ATOM   214  C CG1   . VAL A 1 61  ? 106.987 123.417 117.240 1.00 44.61  ? 36  VAL R CG1   1 
ATOM   215  C CG2   . VAL A 1 61  ? 104.557 123.562 117.800 1.00 44.61  ? 36  VAL R CG2   1 
ATOM   216  N N     . VAL A 1 62  ? 107.264 119.904 117.295 1.00 41.25  ? 37  VAL R N     1 
ATOM   217  C CA    . VAL A 1 62  ? 108.532 119.225 117.039 1.00 41.25  ? 37  VAL R CA    1 
ATOM   218  C C     . VAL A 1 62  ? 108.400 118.267 115.862 1.00 41.25  ? 37  VAL R C     1 
ATOM   219  O O     . VAL A 1 62  ? 109.267 118.223 114.981 1.00 41.25  ? 37  VAL R O     1 
ATOM   220  C CB    . VAL A 1 62  ? 109.017 118.498 118.305 1.00 41.25  ? 37  VAL R CB    1 
ATOM   221  C CG1   . VAL A 1 62  ? 110.157 117.551 117.963 1.00 41.25  ? 37  VAL R CG1   1 
ATOM   222  C CG2   . VAL A 1 62  ? 109.453 119.504 119.357 1.00 41.25  ? 37  VAL R CG2   1 
ATOM   223  N N     . LYS A 1 63  ? 107.321 117.483 115.825 1.00 43.51  ? 38  LYS R N     1 
ATOM   224  C CA    . LYS A 1 63  ? 107.162 116.504 114.754 1.00 43.51  ? 38  LYS R CA    1 
ATOM   225  C C     . LYS A 1 63  ? 106.873 117.154 113.407 1.00 43.51  ? 38  LYS R C     1 
ATOM   226  O O     . LYS A 1 63  ? 107.285 116.618 112.372 1.00 43.51  ? 38  LYS R O     1 
ATOM   227  C CB    . LYS A 1 63  ? 106.047 115.513 115.099 1.00 43.51  ? 38  LYS R CB    1 
ATOM   228  C CG    . LYS A 1 63  ? 106.269 114.664 116.359 1.00 43.51  ? 38  LYS R CG    1 
ATOM   229  C CD    . LYS A 1 63  ? 107.730 114.285 116.589 1.00 43.51  ? 38  LYS R CD    1 
ATOM   230  C CE    . LYS A 1 63  ? 107.920 113.597 117.931 1.00 43.51  ? 38  LYS R CE    1 
ATOM   231  N NZ    . LYS A 1 63  ? 109.347 113.253 118.180 1.00 43.51  ? 38  LYS R NZ    1 
ATOM   232  N N     . LEU A 1 64  ? 106.176 118.292 113.386 1.00 45.67  ? 39  LEU R N     1 
ATOM   233  C CA    . LEU A 1 64  ? 105.842 118.911 112.106 1.00 45.67  ? 39  LEU R CA    1 
ATOM   234  C C     . LEU A 1 64  ? 107.091 119.346 111.348 1.00 45.67  ? 39  LEU R C     1 
ATOM   235  O O     . LEU A 1 64  ? 107.160 119.196 110.122 1.00 45.67  ? 39  LEU R O     1 
ATOM   236  C CB    . LEU A 1 64  ? 104.904 120.098 112.322 1.00 45.67  ? 39  LEU R CB    1 
ATOM   237  C CG    . LEU A 1 64  ? 103.437 119.793 112.013 1.00 45.67  ? 39  LEU R CG    1 
ATOM   238  C CD1   . LEU A 1 64  ? 102.876 118.786 113.000 1.00 45.67  ? 39  LEU R CD1   1 
ATOM   239  C CD2   . LEU A 1 64  ? 102.611 121.069 112.019 1.00 45.67  ? 39  LEU R CD2   1 
ATOM   240  N N     . ASN A 1 65  ? 108.086 119.886 112.052 1.00 42.86  ? 40  ASN R N     1 
ATOM   241  C CA    . ASN A 1 65  ? 109.284 120.406 111.409 1.00 42.86  ? 40  ASN R CA    1 
ATOM   242  C C     . ASN A 1 65  ? 110.432 119.423 111.580 1.00 42.86  ? 40  ASN R C     1 
ATOM   243  O O     . ASN A 1 65  ? 110.908 119.237 112.710 1.00 42.86  ? 40  ASN R O     1 
ATOM   244  C CB    . ASN A 1 65  ? 109.655 121.763 112.000 1.00 42.86  ? 40  ASN R CB    1 
ATOM   245  C CG    . ASN A 1 65  ? 108.667 122.846 111.625 1.00 42.86  ? 40  ASN R CG    1 
ATOM   246  O OD1   . ASN A 1 65  ? 107.462 122.695 111.821 1.00 42.86  ? 40  ASN R OD1   1 
ATOM   247  N ND2   . ASN A 1 65  ? 109.173 123.948 111.082 1.00 42.86  ? 40  ASN R ND2   1 
ATOM   248  N N     . PRO A 1 66  ? 110.913 118.776 110.513 1.00 36.67  ? 41  PRO R N     1 
ATOM   249  C CA    . PRO A 1 66  ? 112.075 117.884 110.657 1.00 36.67  ? 41  PRO R CA    1 
ATOM   250  C C     . PRO A 1 66  ? 113.335 118.592 111.126 1.00 36.67  ? 41  PRO R C     1 
ATOM   251  O O     . PRO A 1 66  ? 114.245 117.922 111.631 1.00 36.67  ? 41  PRO R O     1 
ATOM   252  C CB    . PRO A 1 66  ? 112.256 117.313 109.246 1.00 36.67  ? 41  PRO R CB    1 
ATOM   253  C CG    . PRO A 1 66  ? 110.912 117.419 108.623 1.00 36.67  ? 41  PRO R CG    1 
ATOM   254  C CD    . PRO A 1 66  ? 110.329 118.690 109.164 1.00 36.67  ? 41  PRO R CD    1 
ATOM   255  N N     . SER A 1 67  ? 113.426 119.914 110.968 1.00 40.13  ? 42  SER R N     1 
ATOM   256  C CA    . SER A 1 67  ? 114.594 120.641 111.449 1.00 40.13  ? 42  SER R CA    1 
ATOM   257  C C     . SER A 1 67  ? 114.689 120.641 112.968 1.00 40.13  ? 42  SER R C     1 
ATOM   258  O O     . SER A 1 67  ? 115.759 120.941 113.509 1.00 40.13  ? 42  SER R O     1 
ATOM   259  C CB    . SER A 1 67  ? 114.562 122.081 110.935 1.00 40.13  ? 42  SER R CB    1 
ATOM   260  O OG    . SER A 1 67  ? 115.672 122.817 111.417 1.00 40.13  ? 42  SER R OG    1 
ATOM   261  N N     . LEU A 1 68  ? 113.600 120.313 113.666 1.00 41.82  ? 43  LEU R N     1 
ATOM   262  C CA    . LEU A 1 68  ? 113.558 120.310 115.123 1.00 41.82  ? 43  LEU R CA    1 
ATOM   263  C C     . LEU A 1 68  ? 113.699 118.905 115.699 1.00 41.82  ? 43  LEU R C     1 
ATOM   264  O O     . LEU A 1 68  ? 113.057 118.579 116.703 1.00 41.82  ? 43  LEU R O     1 
ATOM   265  C CB    . LEU A 1 68  ? 112.259 120.951 115.612 1.00 41.82  ? 43  LEU R CB    1 
ATOM   266  C CG    . LEU A 1 68  ? 111.958 122.374 115.133 1.00 41.82  ? 43  LEU R CG    1 
ATOM   267  C CD1   . LEU A 1 68  ? 110.581 122.796 115.616 1.00 41.82  ? 43  LEU R CD1   1 
ATOM   268  C CD2   . LEU A 1 68  ? 113.003 123.379 115.593 1.00 41.82  ? 43  LEU R CD2   1 
ATOM   269  N N     . GLN A 1 69  ? 114.533 118.067 115.084 1.00 39.01  ? 44  GLN R N     1 
ATOM   270  C CA    . GLN A 1 69  ? 114.670 116.674 115.493 1.00 39.01  ? 44  GLN R CA    1 
ATOM   271  C C     . GLN A 1 69  ? 116.122 116.341 115.808 1.00 39.01  ? 44  GLN R C     1 
ATOM   272  O O     . GLN A 1 69  ? 116.659 115.344 115.315 1.00 39.01  ? 44  GLN R O     1 
ATOM   273  C CB    . GLN A 1 69  ? 114.131 115.741 114.408 1.00 39.01  ? 44  GLN R CB    1 
ATOM   274  C CG    . GLN A 1 69  ? 112.755 116.130 113.895 1.00 39.01  ? 44  GLN R CG    1 
ATOM   275  C CD    . GLN A 1 69  ? 112.007 114.961 113.284 1.00 39.01  ? 44  GLN R CD    1 
ATOM   276  O OE1   . GLN A 1 69  ? 112.607 113.957 112.901 1.00 39.01  ? 44  GLN R OE1   1 
ATOM   277  N NE2   . GLN A 1 69  ? 110.689 115.087 113.190 1.00 39.01  ? 44  GLN R NE2   1 
ATOM   278  N N     . THR A 1 70  ? 116.762 117.176 116.625 1.00 36.47  ? 45  THR R N     1 
ATOM   279  C CA    . THR A 1 70  ? 118.144 116.956 117.031 1.00 36.47  ? 45  THR R CA    1 
ATOM   280  C C     . THR A 1 70  ? 118.218 116.692 118.529 1.00 36.47  ? 45  THR R C     1 
ATOM   281  O O     . THR A 1 70  ? 117.186 116.542 119.191 1.00 36.47  ? 45  THR R O     1 
ATOM   282  C CB    . THR A 1 70  ? 119.016 118.157 116.658 1.00 36.47  ? 45  THR R CB    1 
ATOM   283  O OG1   . THR A 1 70  ? 118.675 119.276 117.486 1.00 36.47  ? 45  THR R OG1   1 
ATOM   284  C CG2   . THR A 1 70  ? 118.820 118.528 115.196 1.00 36.47  ? 45  THR R CG2   1 
ATOM   285  N N     . THR A 1 71  ? 119.434 116.635 119.071 1.00 31.88  ? 46  THR R N     1 
ATOM   286  C CA    . THR A 1 71  ? 119.657 116.204 120.447 1.00 31.88  ? 46  THR R CA    1 
ATOM   287  C C     . THR A 1 71  ? 118.835 117.003 121.454 1.00 31.88  ? 46  THR R C     1 
ATOM   288  O O     . THR A 1 71  ? 118.117 116.417 122.278 1.00 31.88  ? 46  THR R O     1 
ATOM   289  C CB    . THR A 1 71  ? 121.144 116.324 120.796 1.00 31.88  ? 46  THR R CB    1 
ATOM   290  O OG1   . THR A 1 71  ? 121.500 117.705 120.919 1.00 31.88  ? 46  THR R OG1   1 
ATOM   291  C CG2   . THR A 1 71  ? 122.004 115.698 119.707 1.00 31.88  ? 46  THR R CG2   1 
ATOM   292  N N     . THR A 1 72  ? 118.922 118.334 121.400 1.00 33.13  ? 47  THR R N     1 
ATOM   293  C CA    . THR A 1 72  ? 118.173 119.157 122.342 1.00 33.13  ? 47  THR R CA    1 
ATOM   294  C C     . THR A 1 72  ? 116.682 118.869 122.238 1.00 33.13  ? 47  THR R C     1 
ATOM   295  O O     . THR A 1 72  ? 115.982 118.772 123.253 1.00 33.13  ? 47  THR R O     1 
ATOM   296  C CB    . THR A 1 72  ? 118.461 120.641 122.097 1.00 33.13  ? 47  THR R CB    1 
ATOM   297  O OG1   . THR A 1 72  ? 117.938 121.418 123.182 1.00 33.13  ? 47  THR R OG1   1 
ATOM   298  C CG2   . THR A 1 72  ? 117.842 121.115 120.788 1.00 33.13  ? 47  THR R CG2   1 
ATOM   299  N N     . PHE A 1 73  ? 116.178 118.707 121.014 1.00 36.48  ? 48  PHE R N     1 
ATOM   300  C CA    . PHE A 1 73  ? 114.767 118.398 120.843 1.00 36.48  ? 48  PHE R CA    1 
ATOM   301  C C     . PHE A 1 73  ? 114.437 116.967 121.238 1.00 36.48  ? 48  PHE R C     1 
ATOM   302  O O     . PHE A 1 73  ? 113.310 116.709 121.660 1.00 36.48  ? 48  PHE R O     1 
ATOM   303  C CB    . PHE A 1 73  ? 114.341 118.674 119.403 1.00 36.48  ? 48  PHE R CB    1 
ATOM   304  C CG    . PHE A 1 73  ? 114.378 120.129 119.042 1.00 36.48  ? 48  PHE R CG    1 
ATOM   305  C CD1   . PHE A 1 73  ? 113.339 120.968 119.406 1.00 36.48  ? 48  PHE R CD1   1 
ATOM   306  C CD2   . PHE A 1 73  ? 115.456 120.662 118.355 1.00 36.48  ? 48  PHE R CD2   1 
ATOM   307  C CE1   . PHE A 1 73  ? 113.367 122.309 119.085 1.00 36.48  ? 48  PHE R CE1   1 
ATOM   308  C CE2   . PHE A 1 73  ? 115.489 122.004 118.030 1.00 36.48  ? 48  PHE R CE2   1 
ATOM   309  C CZ    . PHE A 1 73  ? 114.445 122.828 118.398 1.00 36.48  ? 48  PHE R CZ    1 
ATOM   310  N N     . TYR A 1 74  ? 115.390 116.038 121.143 1.00 31.95  ? 49  TYR R N     1 
ATOM   311  C CA    . TYR A 1 74  ? 115.176 114.712 121.714 1.00 31.95  ? 49  TYR R CA    1 
ATOM   312  C C     . TYR A 1 74  ? 114.914 114.817 123.212 1.00 31.95  ? 49  TYR R C     1 
ATOM   313  O O     . TYR A 1 74  ? 113.947 114.250 123.738 1.00 31.95  ? 49  TYR R O     1 
ATOM   314  C CB    . TYR A 1 74  ? 116.390 113.816 121.444 1.00 31.95  ? 49  TYR R CB    1 
ATOM   315  C CG    . TYR A 1 74  ? 116.489 113.262 120.035 1.00 31.95  ? 49  TYR R CG    1 
ATOM   316  C CD1   . TYR A 1 74  ? 115.526 113.549 119.073 1.00 31.95  ? 49  TYR R CD1   1 
ATOM   317  C CD2   . TYR A 1 74  ? 117.552 112.448 119.670 1.00 31.95  ? 49  TYR R CD2   1 
ATOM   318  C CE1   . TYR A 1 74  ? 115.623 113.040 117.793 1.00 31.95  ? 49  TYR R CE1   1 
ATOM   319  C CE2   . TYR A 1 74  ? 117.657 111.936 118.393 1.00 31.95  ? 49  TYR R CE2   1 
ATOM   320  C CZ    . TYR A 1 74  ? 116.690 112.235 117.458 1.00 31.95  ? 49  TYR R CZ    1 
ATOM   321  O OH    . TYR A 1 74  ? 116.791 111.726 116.184 1.00 31.95  ? 49  TYR R OH    1 
ATOM   322  N N     . PHE A 1 75  ? 115.770 115.562 123.915 1.00 26.24  ? 50  PHE R N     1 
ATOM   323  C CA    . PHE A 1 75  ? 115.572 115.738 125.351 1.00 26.24  ? 50  PHE R CA    1 
ATOM   324  C C     . PHE A 1 75  ? 114.256 116.453 125.640 1.00 26.24  ? 50  PHE R C     1 
ATOM   325  O O     . PHE A 1 75  ? 113.527 116.086 126.572 1.00 26.24  ? 50  PHE R O     1 
ATOM   326  C CB    . PHE A 1 75  ? 116.746 116.513 125.946 1.00 26.24  ? 50  PHE R CB    1 
ATOM   327  C CG    . PHE A 1 75  ? 118.042 115.758 125.919 1.00 26.24  ? 50  PHE R CG    1 
ATOM   328  C CD1   . PHE A 1 75  ? 118.268 114.709 126.790 1.00 26.24  ? 50  PHE R CD1   1 
ATOM   329  C CD2   . PHE A 1 75  ? 119.035 116.098 125.019 1.00 26.24  ? 50  PHE R CD2   1 
ATOM   330  C CE1   . PHE A 1 75  ? 119.460 114.013 126.765 1.00 26.24  ? 50  PHE R CE1   1 
ATOM   331  C CE2   . PHE A 1 75  ? 120.227 115.406 124.988 1.00 26.24  ? 50  PHE R CE2   1 
ATOM   332  C CZ    . PHE A 1 75  ? 120.440 114.362 125.863 1.00 26.24  ? 50  PHE R CZ    1 
ATOM   333  N N     . ILE A 1 76  ? 113.934 117.476 124.848 1.00 29.89  ? 51  ILE R N     1 
ATOM   334  C CA    . ILE A 1 76  ? 112.718 118.244 125.084 1.00 29.89  ? 51  ILE R CA    1 
ATOM   335  C C     . ILE A 1 76  ? 111.481 117.377 124.881 1.00 29.89  ? 51  ILE R C     1 
ATOM   336  O O     . ILE A 1 76  ? 110.519 117.466 125.649 1.00 29.89  ? 51  ILE R O     1 
ATOM   337  C CB    . ILE A 1 76  ? 112.694 119.494 124.186 1.00 29.89  ? 51  ILE R CB    1 
ATOM   338  C CG1   . ILE A 1 76  ? 113.722 120.511 124.685 1.00 29.89  ? 51  ILE R CG1   1 
ATOM   339  C CG2   . ILE A 1 76  ? 111.300 120.106 124.161 1.00 29.89  ? 51  ILE R CG2   1 
ATOM   340  C CD1   . ILE A 1 76  ? 113.978 121.649 123.726 1.00 29.89  ? 51  ILE R CD1   1 
ATOM   341  N N     . VAL A 1 77  ? 111.474 116.530 123.849 1.00 32.21  ? 52  VAL R N     1 
ATOM   342  C CA    . VAL A 1 77  ? 110.313 115.672 123.628 1.00 32.21  ? 52  VAL R CA    1 
ATOM   343  C C     . VAL A 1 77  ? 110.233 114.588 124.692 1.00 32.21  ? 52  VAL R C     1 
ATOM   344  O O     . VAL A 1 77  ? 109.134 114.169 125.072 1.00 32.21  ? 52  VAL R O     1 
ATOM   345  C CB    . VAL A 1 77  ? 110.325 115.066 122.211 1.00 32.21  ? 52  VAL R CB    1 
ATOM   346  C CG1   . VAL A 1 77  ? 110.299 116.165 121.164 1.00 32.21  ? 52  VAL R CG1   1 
ATOM   347  C CG2   . VAL A 1 77  ? 111.524 114.152 122.015 1.00 32.21  ? 52  VAL R CG2   1 
ATOM   348  N N     . SER A 1 78  ? 111.372 114.102 125.190 1.00 28.62  ? 53  SER R N     1 
ATOM   349  C CA    . SER A 1 78  ? 111.318 113.169 126.312 1.00 28.62  ? 53  SER R CA    1 
ATOM   350  C C     . SER A 1 78  ? 110.652 113.824 127.515 1.00 28.62  ? 53  SER R C     1 
ATOM   351  O O     . SER A 1 78  ? 109.779 113.232 128.165 1.00 28.62  ? 53  SER R O     1 
ATOM   352  C CB    . SER A 1 78  ? 112.723 112.693 126.669 1.00 28.62  ? 53  SER R CB    1 
ATOM   353  O OG    . SER A 1 78  ? 113.498 113.751 127.204 1.00 28.62  ? 53  SER R OG    1 
ATOM   354  N N     . LEU A 1 79  ? 111.044 115.064 127.814 1.00 27.04  ? 54  LEU R N     1 
ATOM   355  C CA    . LEU A 1 79  ? 110.392 115.813 128.883 1.00 27.04  ? 54  LEU R CA    1 
ATOM   356  C C     . LEU A 1 79  ? 108.907 115.996 128.591 1.00 27.04  ? 54  LEU R C     1 
ATOM   357  O O     . LEU A 1 79  ? 108.070 115.942 129.497 1.00 27.04  ? 54  LEU R O     1 
ATOM   358  C CB    . LEU A 1 79  ? 111.078 117.167 129.063 1.00 27.04  ? 54  LEU R CB    1 
ATOM   359  C CG    . LEU A 1 79  ? 110.617 118.011 130.253 1.00 27.04  ? 54  LEU R CG    1 
ATOM   360  C CD1   . LEU A 1 79  ? 111.738 118.904 130.734 1.00 27.04  ? 54  LEU R CD1   1 
ATOM   361  C CD2   . LEU A 1 79  ? 109.411 118.858 129.892 1.00 27.04  ? 54  LEU R CD2   1 
ATOM   362  N N     . ALA A 1 80  ? 108.567 116.239 127.325 1.00 31.75  ? 55  ALA R N     1 
ATOM   363  C CA    . ALA A 1 80  ? 107.171 116.441 126.958 1.00 31.75  ? 55  ALA R CA    1 
ATOM   364  C C     . ALA A 1 80  ? 106.344 115.190 127.223 1.00 31.75  ? 55  ALA R C     1 
ATOM   365  O O     . ALA A 1 80  ? 105.230 115.276 127.746 1.00 31.75  ? 55  ALA R O     1 
ATOM   366  C CB    . ALA A 1 80  ? 107.070 116.849 125.489 1.00 31.75  ? 55  ALA R CB    1 
ATOM   367  N N     . LEU A 1 81  ? 106.867 114.019 126.860 1.00 31.18  ? 56  LEU R N     1 
ATOM   368  C CA    . LEU A 1 81  ? 106.159 112.776 127.160 1.00 31.18  ? 56  LEU R CA    1 
ATOM   369  C C     . LEU A 1 81  ? 106.058 112.549 128.663 1.00 31.18  ? 56  LEU R C     1 
ATOM   370  O O     . LEU A 1 81  ? 105.022 112.088 129.159 1.00 31.18  ? 56  LEU R O     1 
ATOM   371  C CB    . LEU A 1 81  ? 106.842 111.586 126.485 1.00 31.18  ? 56  LEU R CB    1 
ATOM   372  C CG    . LEU A 1 81  ? 106.541 111.362 124.999 1.00 31.18  ? 56  LEU R CG    1 
ATOM   373  C CD1   . LEU A 1 81  ? 107.184 112.405 124.108 1.00 31.18  ? 56  LEU R CD1   1 
ATOM   374  C CD2   . LEU A 1 81  ? 106.992 109.968 124.591 1.00 31.18  ? 56  LEU R CD2   1 
ATOM   375  N N     . ALA A 1 82  ? 107.120 112.865 129.406 1.00 28.83  ? 57  ALA R N     1 
ATOM   376  C CA    . ALA A 1 82  ? 107.050 112.739 130.858 1.00 28.83  ? 57  ALA R CA    1 
ATOM   377  C C     . ALA A 1 82  ? 105.937 113.611 131.425 1.00 28.83  ? 57  ALA R C     1 
ATOM   378  O O     . ALA A 1 82  ? 105.175 113.177 132.296 1.00 28.83  ? 57  ALA R O     1 
ATOM   379  C CB    . ALA A 1 82  ? 108.394 113.111 131.485 1.00 28.83  ? 57  ALA R CB    1 
ATOM   380  N N     . ASP A 1 83  ? 105.819 114.842 130.930 1.00 31.30  ? 58  ASP R N     1 
ATOM   381  C CA    . ASP A 1 83  ? 104.788 115.748 131.421 1.00 31.30  ? 58  ASP R CA    1 
ATOM   382  C C     . ASP A 1 83  ? 103.394 115.326 130.973 1.00 31.30  ? 58  ASP R C     1 
ATOM   383  O O     . ASP A 1 83  ? 102.431 115.496 131.726 1.00 31.30  ? 58  ASP R O     1 
ATOM   384  C CB    . ASP A 1 83  ? 105.083 117.175 130.959 1.00 31.30  ? 58  ASP R CB    1 
ATOM   385  C CG    . ASP A 1 83  ? 106.334 117.747 131.601 1.00 31.30  ? 58  ASP R CG    1 
ATOM   386  O OD1   . ASP A 1 83  ? 106.869 117.114 132.535 1.00 31.30  ? 58  ASP R OD1   1 
ATOM   387  O OD2   . ASP A 1 83  ? 106.778 118.834 131.176 1.00 31.30  ? 58  ASP R OD2   1 
ATOM   388  N N     . ILE A 1 84  ? 103.261 114.772 129.766 1.00 34.04  ? 59  ILE R N     1 
ATOM   389  C CA    . ILE A 1 84  ? 101.982 114.209 129.353 1.00 34.04  ? 59  ILE R CA    1 
ATOM   390  C C     . ILE A 1 84  ? 101.566 113.078 130.273 1.00 34.04  ? 59  ILE R C     1 
ATOM   391  O O     . ILE A 1 84  ? 100.390 112.981 130.637 1.00 34.04  ? 59  ILE R O     1 
ATOM   392  C CB    . ILE A 1 84  ? 102.031 113.712 127.896 1.00 34.04  ? 59  ILE R CB    1 
ATOM   393  C CG1   . ILE A 1 84  ? 102.287 114.881 126.947 1.00 34.04  ? 59  ILE R CG1   1 
ATOM   394  C CG2   . ILE A 1 84  ? 100.734 112.997 127.539 1.00 34.04  ? 59  ILE R CG2   1 
ATOM   395  C CD1   . ILE A 1 84  ? 102.611 114.469 125.526 1.00 34.04  ? 59  ILE R CD1   1 
ATOM   396  N N     . ALA A 1 85  ? 102.499 112.210 130.654 1.00 32.69  ? 60  ALA R N     1 
ATOM   397  C CA    . ALA A 1 85  ? 102.195 111.163 131.618 1.00 32.69  ? 60  ALA R CA    1 
ATOM   398  C C     . ALA A 1 85  ? 101.833 111.723 132.987 1.00 32.69  ? 60  ALA R C     1 
ATOM   399  O O     . ALA A 1 85  ? 100.921 111.204 133.639 1.00 32.69  ? 60  ALA R O     1 
ATOM   400  C CB    . ALA A 1 85  ? 103.382 110.208 131.752 1.00 32.69  ? 60  ALA R CB    1 
ATOM   401  N N     . VAL A 1 86  ? 102.532 112.770 133.437 1.00 31.72  ? 61  VAL R N     1 
ATOM   402  C CA    . VAL A 1 86  ? 102.216 113.410 134.714 1.00 31.72  ? 61  VAL R CA    1 
ATOM   403  C C     . VAL A 1 86  ? 100.901 114.171 134.678 1.00 31.72  ? 61  VAL R C     1 
ATOM   404  O O     . VAL A 1 86  ? 100.346 114.480 135.740 1.00 31.72  ? 61  VAL R O     1 
ATOM   405  C CB    . VAL A 1 86  ? 103.355 114.365 135.130 1.00 31.72  ? 61  VAL R CB    1 
ATOM   406  C CG1   . VAL A 1 86  ? 102.951 115.200 136.335 1.00 31.72  ? 61  VAL R CG1   1 
ATOM   407  C CG2   . VAL A 1 86  ? 104.620 113.581 135.435 1.00 31.72  ? 61  VAL R CG2   1 
ATOM   408  N N     . GLY A 1 87  ? 100.390 114.495 133.497 1.00 36.98  ? 62  GLY R N     1 
ATOM   409  C CA    . GLY A 1 87  ? 99.138  115.220 133.401 1.00 36.98  ? 62  GLY R CA    1 
ATOM   410  C C     . GLY A 1 87  ? 97.937  114.351 133.085 1.00 36.98  ? 62  GLY R C     1 
ATOM   411  O O     . GLY A 1 87  ? 96.803  114.721 133.402 1.00 36.98  ? 62  GLY R O     1 
ATOM   412  N N     . VAL A 1 88  ? 98.167  113.194 132.462 1.00 37.23  ? 63  VAL R N     1 
ATOM   413  C CA    . VAL A 1 88  ? 97.053  112.369 132.002 1.00 37.23  ? 63  VAL R CA    1 
ATOM   414  C C     . VAL A 1 88  ? 96.657  111.342 133.055 1.00 37.23  ? 63  VAL R C     1 
ATOM   415  O O     . VAL A 1 88  ? 95.468  111.158 133.335 1.00 37.23  ? 63  VAL R O     1 
ATOM   416  C CB    . VAL A 1 88  ? 97.405  111.700 130.660 1.00 37.23  ? 63  VAL R CB    1 
ATOM   417  C CG1   . VAL A 1 88  ? 98.558  110.717 130.821 1.00 37.23  ? 63  VAL R CG1   1 
ATOM   418  C CG2   . VAL A 1 88  ? 96.183  111.000 130.084 1.00 37.23  ? 63  VAL R CG2   1 
ATOM   419  N N     . LEU A 1 89  ? 97.631  110.654 133.649 1.00 36.46  ? 64  LEU R N     1 
ATOM   420  C CA    . LEU A 1 89  ? 97.359  109.630 134.653 1.00 36.46  ? 64  LEU R CA    1 
ATOM   421  C C     . LEU A 1 89  ? 97.459  110.183 136.070 1.00 36.46  ? 64  LEU R C     1 
ATOM   422  O O     . LEU A 1 89  ? 96.571  109.951 136.896 1.00 36.46  ? 64  LEU R O     1 
ATOM   423  C CB    . LEU A 1 89  ? 98.326  108.451 134.481 1.00 36.46  ? 64  LEU R CB    1 
ATOM   424  C CG    . LEU A 1 89  ? 98.107  107.559 133.260 1.00 36.46  ? 64  LEU R CG    1 
ATOM   425  C CD1   . LEU A 1 89  ? 99.253  106.574 133.122 1.00 36.46  ? 64  LEU R CD1   1 
ATOM   426  C CD2   . LEU A 1 89  ? 96.777  106.826 133.364 1.00 36.46  ? 64  LEU R CD2   1 
ATOM   427  N N     . VAL A 1 90  ? 98.533  110.917 136.365 1.00 34.24  ? 65  VAL R N     1 
ATOM   428  C CA    . VAL A 1 90  ? 98.760  111.389 137.724 1.00 34.24  ? 65  VAL R CA    1 
ATOM   429  C C     . VAL A 1 90  ? 97.662  112.335 138.190 1.00 34.24  ? 65  VAL R C     1 
ATOM   430  O O     . VAL A 1 90  ? 97.425  112.448 139.394 1.00 34.24  ? 65  VAL R O     1 
ATOM   431  C CB    . VAL A 1 90  ? 100.145 112.054 137.822 1.00 34.24  ? 65  VAL R CB    1 
ATOM   432  C CG1   . VAL A 1 90  ? 100.372 112.620 139.213 1.00 34.24  ? 65  VAL R CG1   1 
ATOM   433  C CG2   . VAL A 1 90  ? 101.233 111.058 137.450 1.00 34.24  ? 65  VAL R CG2   1 
ATOM   434  N N     . MET A 1 91  ? 96.974  113.010 137.276 1.00 41.57  ? 66  MET R N     1 
ATOM   435  C CA    . MET A 1 91  ? 95.894  113.913 137.657 1.00 41.57  ? 66  MET R CA    1 
ATOM   436  C C     . MET A 1 91  ? 94.670  113.124 138.124 1.00 41.57  ? 66  MET R C     1 
ATOM   437  O O     . MET A 1 91  ? 94.248  113.277 139.282 1.00 41.57  ? 66  MET R O     1 
ATOM   438  C CB    . MET A 1 91  ? 95.563  114.849 136.488 1.00 41.57  ? 66  MET R CB    1 
ATOM   439  C CG    . MET A 1 91  ? 94.178  115.483 136.525 1.00 41.57  ? 66  MET R CG    1 
ATOM   440  S SD    . MET A 1 91  ? 93.810  116.389 135.009 1.00 41.57  ? 66  MET R SD    1 
ATOM   441  C CE    . MET A 1 91  ? 93.184  115.082 133.955 1.00 41.57  ? 66  MET R CE    1 
ATOM   442  N N     . PRO A 1 92  ? 94.058  112.288 137.272 1.00 40.10  ? 67  PRO R N     1 
ATOM   443  C CA    . PRO A 1 92  ? 92.967  111.441 137.779 1.00 40.10  ? 67  PRO R CA    1 
ATOM   444  C C     . PRO A 1 92  ? 93.397  110.575 138.942 1.00 40.10  ? 67  PRO R C     1 
ATOM   445  O O     . PRO A 1 92  ? 92.603  110.334 139.859 1.00 40.10  ? 67  PRO R O     1 
ATOM   446  C CB    . PRO A 1 92  ? 92.579  110.600 136.557 1.00 40.10  ? 67  PRO R CB    1 
ATOM   447  C CG    . PRO A 1 92  ? 92.988  111.407 135.406 1.00 40.10  ? 67  PRO R CG    1 
ATOM   448  C CD    . PRO A 1 92  ? 94.235  112.119 135.817 1.00 40.10  ? 67  PRO R CD    1 
ATOM   449  N N     . LEU A 1 93  ? 94.641  110.090 138.926 1.00 38.24  ? 68  LEU R N     1 
ATOM   450  C CA    . LEU A 1 93  ? 95.112  109.271 140.035 1.00 38.24  ? 68  LEU R CA    1 
ATOM   451  C C     . LEU A 1 93  ? 95.135  110.061 141.335 1.00 38.24  ? 68  LEU R C     1 
ATOM   452  O O     . LEU A 1 93  ? 94.715  109.548 142.374 1.00 38.24  ? 68  LEU R O     1 
ATOM   453  C CB    . LEU A 1 93  ? 96.502  108.713 139.732 1.00 38.24  ? 68  LEU R CB    1 
ATOM   454  C CG    . LEU A 1 93  ? 96.597  107.412 138.924 1.00 38.24  ? 68  LEU R CG    1 
ATOM   455  C CD1   . LEU A 1 93  ? 98.023  106.886 138.966 1.00 38.24  ? 68  LEU R CD1   1 
ATOM   456  C CD2   . LEU A 1 93  ? 95.619  106.350 139.410 1.00 38.24  ? 68  LEU R CD2   1 
ATOM   457  N N     . ALA A 1 94  ? 95.616  111.305 141.302 1.00 38.54  ? 69  ALA R N     1 
ATOM   458  C CA    . ALA A 1 94  ? 95.610  112.130 142.504 1.00 38.54  ? 69  ALA R CA    1 
ATOM   459  C C     . ALA A 1 94  ? 94.191  112.396 142.983 1.00 38.54  ? 69  ALA R C     1 
ATOM   460  O O     . ALA A 1 94  ? 93.912  112.320 144.187 1.00 38.54  ? 69  ALA R O     1 
ATOM   461  C CB    . ALA A 1 94  ? 96.336  113.448 142.239 1.00 38.54  ? 69  ALA R CB    1 
ATOM   462  N N     . ILE A 1 95  ? 93.281  112.703 142.056 1.00 42.97  ? 70  ILE R N     1 
ATOM   463  C CA    . ILE A 1 95  ? 91.886  112.896 142.449 1.00 42.97  ? 70  ILE R CA    1 
ATOM   464  C C     . ILE A 1 95  ? 91.358  111.645 143.141 1.00 42.97  ? 70  ILE R C     1 
ATOM   465  O O     . ILE A 1 95  ? 90.704  111.724 144.187 1.00 42.97  ? 70  ILE R O     1 
ATOM   466  C CB    . ILE A 1 95  ? 91.022  113.282 141.232 1.00 42.97  ? 70  ILE R CB    1 
ATOM   467  C CG1   . ILE A 1 95  ? 91.601  114.517 140.534 1.00 42.97  ? 70  ILE R CG1   1 
ATOM   468  C CG2   . ILE A 1 95  ? 89.580  113.540 141.662 1.00 42.97  ? 70  ILE R CG2   1 
ATOM   469  C CD1   . ILE A 1 95  ? 90.826  114.959 139.309 1.00 42.97  ? 70  ILE R CD1   1 
ATOM   470  N N     . VAL A 1 96  ? 91.646  110.472 142.576 1.00 42.31  ? 71  VAL R N     1 
ATOM   471  C CA    . VAL A 1 96  ? 91.158  109.223 143.155 1.00 42.31  ? 71  VAL R CA    1 
ATOM   472  C C     . VAL A 1 96  ? 91.754  109.008 144.542 1.00 42.31  ? 71  VAL R C     1 
ATOM   473  O O     . VAL A 1 96  ? 91.053  108.615 145.482 1.00 42.31  ? 71  VAL R O     1 
ATOM   474  C CB    . VAL A 1 96  ? 91.472  108.044 142.216 1.00 42.31  ? 71  VAL R CB    1 
ATOM   475  C CG1   . VAL A 1 96  ? 91.350  106.719 142.955 1.00 42.31  ? 71  VAL R CG1   1 
ATOM   476  C CG2   . VAL A 1 96  ? 90.550  108.073 141.007 1.00 42.31  ? 71  VAL R CG2   1 
ATOM   477  N N     . ILE A 1 97  ? 93.056  109.257 144.692 1.00 41.92  ? 72  ILE R N     1 
ATOM   478  C CA    . ILE A 1 97  ? 93.711  109.111 145.983 1.00 41.92  ? 72  ILE R CA    1 
ATOM   479  C C     . ILE A 1 97  ? 93.100  110.018 147.036 1.00 41.92  ? 72  ILE R C     1 
ATOM   480  O O     . ILE A 1 97  ? 92.944  109.601 148.187 1.00 41.92  ? 72  ILE R O     1 
ATOM   481  C CB    . ILE A 1 97  ? 95.227  109.401 145.874 1.00 41.92  ? 72  ILE R CB    1 
ATOM   482  C CG1   . ILE A 1 97  ? 95.920  108.423 144.919 1.00 41.92  ? 72  ILE R CG1   1 
ATOM   483  C CG2   . ILE A 1 97  ? 95.875  109.349 147.248 1.00 41.92  ? 72  ILE R CG2   1 
ATOM   484  C CD1   . ILE A 1 97  ? 95.893  106.990 145.353 1.00 41.92  ? 72  ILE R CD1   1 
ATOM   485  N N     . SER A 1 98  ? 92.748  111.250 146.671 1.00 45.24  ? 73  SER R N     1 
ATOM   486  C CA    . SER A 1 98  ? 92.162  112.188 147.625 1.00 45.24  ? 73  SER R CA    1 
ATOM   487  C C     . SER A 1 98  ? 90.818  111.687 148.151 1.00 45.24  ? 73  SER R C     1 
ATOM   488  O O     . SER A 1 98  ? 90.523  111.816 149.343 1.00 45.24  ? 73  SER R O     1 
ATOM   489  C CB    . SER A 1 98  ? 92.003  113.565 146.972 1.00 45.24  ? 73  SER R CB    1 
ATOM   490  O OG    . SER A 1 98  ? 90.840  113.613 146.165 1.00 45.24  ? 73  SER R OG    1 
ATOM   491  N N     . LEU A 1 99  ? 89.996  111.113 147.272 1.00 47.76  ? 74  LEU R N     1 
ATOM   492  C CA    . LEU A 1 99  ? 88.653  110.681 147.639 1.00 47.76  ? 74  LEU R CA    1 
ATOM   493  C C     . LEU A 1 99  ? 88.684  109.575 148.689 1.00 47.76  ? 74  LEU R C     1 
ATOM   494  O O     . LEU A 1 99  ? 87.777  109.481 149.522 1.00 47.76  ? 74  LEU R O     1 
ATOM   495  C CB    . LEU A 1 99  ? 87.894  110.208 146.397 1.00 47.76  ? 74  LEU R CB    1 
ATOM   496  C CG    . LEU A 1 99  ? 87.651  111.271 145.322 1.00 47.76  ? 74  LEU R CG    1 
ATOM   497  C CD1   . LEU A 1 99  ? 86.875  110.683 144.156 1.00 47.76  ? 74  LEU R CD1   1 
ATOM   498  C CD2   . LEU A 1 99  ? 86.923  112.478 145.895 1.00 47.76  ? 74  LEU R CD2   1 
ATOM   499  N N     . GLY A 1 100 ? 89.716  108.739 148.661 1.00 51.15  ? 75  GLY R N     1 
ATOM   500  C CA    . GLY A 1 100 ? 89.834  107.672 149.645 1.00 51.15  ? 75  GLY R CA    1 
ATOM   501  C C     . GLY A 1 100 ? 88.775  106.596 149.536 1.00 51.15  ? 75  GLY R C     1 
ATOM   502  O O     . GLY A 1 100 ? 88.216  106.174 150.557 1.00 51.15  ? 75  GLY R O     1 
ATOM   503  N N     . VAL A 1 101 ? 88.485  106.137 148.318 1.00 54.81  ? 76  VAL R N     1 
ATOM   504  C CA    . VAL A 1 101 ? 87.512  105.067 148.131 1.00 54.81  ? 76  VAL R CA    1 
ATOM   505  C C     . VAL A 1 101 ? 88.110  103.746 148.597 1.00 54.81  ? 76  VAL R C     1 
ATOM   506  O O     . VAL A 1 101 ? 89.332  103.548 148.562 1.00 54.81  ? 76  VAL R O     1 
ATOM   507  C CB    . VAL A 1 101 ? 87.079  104.992 146.656 1.00 54.81  ? 76  VAL R CB    1 
ATOM   508  C CG1   . VAL A 1 101 ? 86.012  103.922 146.464 1.00 54.81  ? 76  VAL R CG1   1 
ATOM   509  C CG2   . VAL A 1 101 ? 86.576  106.347 146.178 1.00 54.81  ? 76  VAL R CG2   1 
ATOM   510  N N     . THR A 1 102 ? 87.246  102.830 149.032 1.00 54.79  ? 77  THR R N     1 
ATOM   511  C CA    . THR A 1 102 ? 87.678  101.520 149.515 1.00 54.79  ? 77  THR R CA    1 
ATOM   512  C C     . THR A 1 102 ? 88.072  100.661 148.321 1.00 54.79  ? 77  THR R C     1 
ATOM   513  O O     . THR A 1 102 ? 87.222  99.998  147.718 1.00 54.79  ? 77  THR R O     1 
ATOM   514  C CB    . THR A 1 102 ? 86.566  100.856 150.322 1.00 54.79  ? 77  THR R CB    1 
ATOM   515  O OG1   . THR A 1 102 ? 85.328  100.956 149.608 1.00 54.79  ? 77  THR R OG1   1 
ATOM   516  C CG2   . THR A 1 102 ? 86.420  101.525 151.680 1.00 54.79  ? 77  THR R CG2   1 
ATOM   517  N N     . ILE A 1 103 ? 89.360  100.669 147.977 1.00 53.08  ? 78  ILE R N     1 
ATOM   518  C CA    . ILE A 1 103 ? 89.801  100.036 146.734 1.00 53.08  ? 78  ILE R CA    1 
ATOM   519  C C     . ILE A 1 103 ? 90.988  99.102  146.939 1.00 53.08  ? 78  ILE R C     1 
ATOM   520  O O     . ILE A 1 103 ? 91.816  98.941  146.036 1.00 53.08  ? 78  ILE R O     1 
ATOM   521  C CB    . ILE A 1 103 ? 90.132  101.097 145.667 1.00 53.08  ? 78  ILE R CB    1 
ATOM   522  C CG1   . ILE A 1 103 ? 91.241  102.030 146.153 1.00 53.08  ? 78  ILE R CG1   1 
ATOM   523  C CG2   . ILE A 1 103 ? 88.888  101.897 145.317 1.00 53.08  ? 78  ILE R CG2   1 
ATOM   524  C CD1   . ILE A 1 103 ? 91.809  102.910 145.059 1.00 53.08  ? 78  ILE R CD1   1 
ATOM   525  N N     . HIS A 1 104 ? 91.096  98.495  148.119 1.00 56.64  ? 79  HIS R N     1 
ATOM   526  C CA    . HIS A 1 104 ? 92.126  97.487  148.355 1.00 56.64  ? 79  HIS R CA    1 
ATOM   527  C C     . HIS A 1 104 ? 93.518  98.104  148.430 1.00 56.64  ? 79  HIS R C     1 
ATOM   528  O O     . HIS A 1 104 ? 93.785  99.144  147.820 1.00 56.64  ? 79  HIS R O     1 
ATOM   529  C CB    . HIS A 1 104 ? 92.088  96.420  147.257 1.00 56.64  ? 79  HIS R CB    1 
ATOM   530  C CG    . HIS A 1 104 ? 92.750  95.133  147.640 1.00 56.64  ? 79  HIS R CG    1 
ATOM   531  N ND1   . HIS A 1 104 ? 92.107  94.151  148.363 1.00 56.64  ? 79  HIS R ND1   1 
ATOM   532  C CD2   . HIS A 1 104 ? 93.996  94.665  147.395 1.00 56.64  ? 79  HIS R CD2   1 
ATOM   533  C CE1   . HIS A 1 104 ? 92.930  93.134  148.549 1.00 56.64  ? 79  HIS R CE1   1 
ATOM   534  N NE2   . HIS A 1 104 ? 94.083  93.421  147.972 1.00 56.64  ? 79  HIS R NE2   1 
ATOM   535  N N     . PHE A 1 105 ? 94.411  97.456  149.183 1.00 52.61  ? 80  PHE R N     1 
ATOM   536  C CA    . PHE A 1 105 ? 95.750  97.985  149.414 1.00 52.61  ? 80  PHE R CA    1 
ATOM   537  C C     . PHE A 1 105 ? 96.588  98.066  148.145 1.00 52.61  ? 80  PHE R C     1 
ATOM   538  O O     . PHE A 1 105 ? 97.154  99.129  147.849 1.00 52.61  ? 80  PHE R O     1 
ATOM   539  C CB    . PHE A 1 105 ? 96.465  97.104  150.442 1.00 52.61  ? 80  PHE R CB    1 
ATOM   540  C CG    . PHE A 1 105 ? 97.851  97.566  150.783 1.00 52.61  ? 80  PHE R CG    1 
ATOM   541  C CD1   . PHE A 1 105 ? 98.051  98.629  151.645 1.00 52.61  ? 80  PHE R CD1   1 
ATOM   542  C CD2   . PHE A 1 105 ? 98.956  96.930  150.244 1.00 52.61  ? 80  PHE R CD2   1 
ATOM   543  C CE1   . PHE A 1 105 ? 99.328  99.051  151.961 1.00 52.61  ? 80  PHE R CE1   1 
ATOM   544  C CE2   . PHE A 1 105 ? 100.234 97.348  150.557 1.00 52.61  ? 80  PHE R CE2   1 
ATOM   545  C CZ    . PHE A 1 105 ? 100.420 98.409  151.416 1.00 52.61  ? 80  PHE R CZ    1 
ATOM   546  N N     . TYR A 1 106 ? 96.683  96.976  147.386 1.00 48.85  ? 81  TYR R N     1 
ATOM   547  C CA    . TYR A 1 106 ? 97.631  96.887  146.284 1.00 48.85  ? 81  TYR R CA    1 
ATOM   548  C C     . TYR A 1 106 ? 97.262  97.743  145.085 1.00 48.85  ? 81  TYR R C     1 
ATOM   549  O O     . TYR A 1 106 ? 98.160  98.272  144.431 1.00 48.85  ? 81  TYR R O     1 
ATOM   550  C CB    . TYR A 1 106 ? 97.786  95.429  145.836 1.00 48.85  ? 81  TYR R CB    1 
ATOM   551  C CG    . TYR A 1 106 ? 98.713  94.634  146.728 1.00 48.85  ? 81  TYR R CG    1 
ATOM   552  C CD1   . TYR A 1 106 ? 100.051 94.981  146.855 1.00 48.85  ? 81  TYR R CD1   1 
ATOM   553  C CD2   . TYR A 1 106 ? 98.248  93.546  147.452 1.00 48.85  ? 81  TYR R CD2   1 
ATOM   554  C CE1   . TYR A 1 106 ? 100.901 94.264  147.672 1.00 48.85  ? 81  TYR R CE1   1 
ATOM   555  C CE2   . TYR A 1 106 ? 99.092  92.821  148.273 1.00 48.85  ? 81  TYR R CE2   1 
ATOM   556  C CZ    . TYR A 1 106 ? 100.416 93.185  148.379 1.00 48.85  ? 81  TYR R CZ    1 
ATOM   557  O OH    . TYR A 1 106 ? 101.261 92.468  149.194 1.00 48.85  ? 81  TYR R OH    1 
ATOM   558  N N     . SER A 1 107 ? 95.975  97.912  144.783 1.00 48.86  ? 82  SER R N     1 
ATOM   559  C CA    . SER A 1 107 ? 95.598  98.852  143.732 1.00 48.86  ? 82  SER R CA    1 
ATOM   560  C C     . SER A 1 107 ? 96.024  100.269 144.095 1.00 48.86  ? 82  SER R C     1 
ATOM   561  O O     . SER A 1 107 ? 96.553  101.006 143.253 1.00 48.86  ? 82  SER R O     1 
ATOM   562  C CB    . SER A 1 107 ? 94.091  98.789  143.488 1.00 48.86  ? 82  SER R CB    1 
ATOM   563  O OG    . SER A 1 107 ? 93.754  97.679  142.675 1.00 48.86  ? 82  SER R OG    1 
ATOM   564  N N     . CYS A 1 108 ? 95.809  100.662 145.352 1.00 47.75  ? 83  CYS R N     1 
ATOM   565  C CA    . CYS A 1 108 ? 96.235  101.977 145.817 1.00 47.75  ? 83  CYS R CA    1 
ATOM   566  C C     . CYS A 1 108 ? 97.747  102.132 145.701 1.00 47.75  ? 83  CYS R C     1 
ATOM   567  O O     . CYS A 1 108 ? 98.252  103.169 145.247 1.00 47.75  ? 83  CYS R O     1 
ATOM   568  C CB    . CYS A 1 108 ? 95.779  102.174 147.264 1.00 47.75  ? 83  CYS R CB    1 
ATOM   569  S SG    . CYS A 1 108 ? 95.952  103.852 147.889 1.00 47.75  ? 83  CYS R SG    1 
ATOM   570  N N     . LEU A 1 109 ? 98.490  101.104 146.120 1.00 41.73  ? 84  LEU R N     1 
ATOM   571  C CA    . LEU A 1 109 ? 99.942  101.156 145.996 1.00 41.73  ? 84  LEU R CA    1 
ATOM   572  C C     . LEU A 1 109 ? 100.355 101.288 144.536 1.00 41.73  ? 84  LEU R C     1 
ATOM   573  O O     . LEU A 1 109 ? 101.310 102.003 144.213 1.00 41.73  ? 84  LEU R O     1 
ATOM   574  C CB    . LEU A 1 109 ? 100.566 99.911  146.625 1.00 41.73  ? 84  LEU R CB    1 
ATOM   575  C CG    . LEU A 1 109 ? 102.088 99.929  146.779 1.00 41.73  ? 84  LEU R CG    1 
ATOM   576  C CD1   . LEU A 1 109 ? 102.512 100.937 147.833 1.00 41.73  ? 84  LEU R CD1   1 
ATOM   577  C CD2   . LEU A 1 109 ? 102.607 98.545  147.126 1.00 41.73  ? 84  LEU R CD2   1 
ATOM   578  N N     . PHE A 1 110 ? 99.643  100.605 143.638 1.00 39.95  ? 85  PHE R N     1 
ATOM   579  C CA    . PHE A 1 110 ? 99.927  100.725 142.213 1.00 39.95  ? 85  PHE R CA    1 
ATOM   580  C C     . PHE A 1 110 ? 99.717  102.153 141.724 1.00 39.95  ? 85  PHE R C     1 
ATOM   581  O O     . PHE A 1 110 ? 100.544 102.684 140.974 1.00 39.95  ? 85  PHE R O     1 
ATOM   582  C CB    . PHE A 1 110 ? 99.047  99.752  141.427 1.00 39.95  ? 85  PHE R CB    1 
ATOM   583  C CG    . PHE A 1 110 ? 99.345  99.712  139.956 1.00 39.95  ? 85  PHE R CG    1 
ATOM   584  C CD1   . PHE A 1 110 ? 100.450 99.031  139.477 1.00 39.95  ? 85  PHE R CD1   1 
ATOM   585  C CD2   . PHE A 1 110 ? 98.518  100.357 139.052 1.00 39.95  ? 85  PHE R CD2   1 
ATOM   586  C CE1   . PHE A 1 110 ? 100.725 98.993  138.125 1.00 39.95  ? 85  PHE R CE1   1 
ATOM   587  C CE2   . PHE A 1 110 ? 98.788  100.321 137.700 1.00 39.95  ? 85  PHE R CE2   1 
ATOM   588  C CZ    . PHE A 1 110 ? 99.894  99.639  137.236 1.00 39.95  ? 85  PHE R CZ    1 
ATOM   589  N N     . MET A 1 111 ? 98.614  102.789 142.128 1.00 41.63  ? 86  MET R N     1 
ATOM   590  C CA    . MET A 1 111 ? 98.378  104.169 141.705 1.00 41.63  ? 86  MET R CA    1 
ATOM   591  C C     . MET A 1 111 ? 99.482  105.088 142.213 1.00 41.63  ? 86  MET R C     1 
ATOM   592  O O     . MET A 1 111 ? 99.999  105.938 141.471 1.00 41.63  ? 86  MET R O     1 
ATOM   593  C CB    . MET A 1 111 ? 97.015  104.667 142.194 1.00 41.63  ? 86  MET R CB    1 
ATOM   594  C CG    . MET A 1 111 ? 95.885  103.662 142.121 1.00 41.63  ? 86  MET R CG    1 
ATOM   595  S SD    . MET A 1 111 ? 94.262  104.434 142.254 1.00 41.63  ? 86  MET R SD    1 
ATOM   596  C CE    . MET A 1 111 ? 93.203  103.077 141.761 1.00 41.63  ? 86  MET R CE    1 
ATOM   597  N N     . THR A 1 112 ? 99.859  104.931 143.483 1.00 37.56  ? 87  THR R N     1 
ATOM   598  C CA    . THR A 1 112 ? 100.913 105.773 144.040 1.00 37.56  ? 87  THR R CA    1 
ATOM   599  C C     . THR A 1 112 ? 102.228 105.561 143.302 1.00 37.56  ? 87  THR R C     1 
ATOM   600  O O     . THR A 1 112 ? 102.953 106.522 143.014 1.00 37.56  ? 87  THR R O     1 
ATOM   601  C CB    . THR A 1 112 ? 101.086 105.491 145.531 1.00 37.56  ? 87  THR R CB    1 
ATOM   602  O OG1   . THR A 1 112 ? 101.625 104.176 145.710 1.00 37.56  ? 87  THR R OG1   1 
ATOM   603  C CG2   . THR A 1 112 ? 99.757  105.608 146.265 1.00 37.56  ? 87  THR R CG2   1 
ATOM   604  N N     . CYS A 1 113 ? 102.552 104.308 142.981 1.00 35.34  ? 88  CYS R N     1 
ATOM   605  C CA    . CYS A 1 113 ? 103.800 104.030 142.283 1.00 35.34  ? 88  CYS R CA    1 
ATOM   606  C C     . CYS A 1 113 ? 103.780 104.597 140.869 1.00 35.34  ? 88  CYS R C     1 
ATOM   607  O O     . CYS A 1 113 ? 104.809 105.063 140.370 1.00 35.34  ? 88  CYS R O     1 
ATOM   608  C CB    . CYS A 1 113 ? 104.063 102.527 142.264 1.00 35.34  ? 88  CYS R CB    1 
ATOM   609  S SG    . CYS A 1 113 ? 104.895 101.925 143.750 1.00 35.34  ? 88  CYS R SG    1 
ATOM   610  N N     . LEU A 1 114 ? 102.622 104.562 140.202 1.00 34.81  ? 89  LEU R N     1 
ATOM   611  C CA    . LEU A 1 114 ? 102.517 105.207 138.897 1.00 34.81  ? 89  LEU R CA    1 
ATOM   612  C C     . LEU A 1 114 ? 102.792 106.701 139.009 1.00 34.81  ? 89  LEU R C     1 
ATOM   613  O O     . LEU A 1 114 ? 103.549 107.273 138.207 1.00 34.81  ? 89  LEU R O     1 
ATOM   614  C CB    . LEU A 1 114 ? 101.134 104.967 138.294 1.00 34.81  ? 89  LEU R CB    1 
ATOM   615  C CG    . LEU A 1 114 ? 100.807 103.543 137.840 1.00 34.81  ? 89  LEU R CG    1 
ATOM   616  C CD1   . LEU A 1 114 ? 99.410  103.501 137.236 1.00 34.81  ? 89  LEU R CD1   1 
ATOM   617  C CD2   . LEU A 1 114 ? 101.841 103.022 136.851 1.00 34.81  ? 89  LEU R CD2   1 
ATOM   618  N N     . MET A 1 115 ? 102.191 107.346 140.010 1.00 33.40  ? 90  MET R N     1 
ATOM   619  C CA    . MET A 1 115 ? 102.448 108.763 140.239 1.00 33.40  ? 90  MET R CA    1 
ATOM   620  C C     . MET A 1 115 ? 103.941 109.017 140.403 1.00 33.40  ? 90  MET R C     1 
ATOM   621  O O     . MET A 1 115 ? 104.513 109.927 139.784 1.00 33.40  ? 90  MET R O     1 
ATOM   622  C CB    . MET A 1 115 ? 101.684 109.231 141.479 1.00 33.40  ? 90  MET R CB    1 
ATOM   623  C CG    . MET A 1 115 ? 100.175 109.272 141.307 1.00 33.40  ? 90  MET R CG    1 
ATOM   624  S SD    . MET A 1 115 ? 99.307  109.363 142.883 1.00 33.40  ? 90  MET R SD    1 
ATOM   625  C CE    . MET A 1 115 ? 98.773  111.070 142.876 1.00 33.40  ? 90  MET R CE    1 
ATOM   626  N N     . LEU A 1 116 ? 104.590 108.209 141.243 1.00 31.11  ? 91  LEU R N     1 
ATOM   627  C CA    . LEU A 1 116 ? 106.007 108.409 141.524 1.00 31.11  ? 91  LEU R CA    1 
ATOM   628  C C     . LEU A 1 116 ? 106.854 108.226 140.271 1.00 31.11  ? 91  LEU R C     1 
ATOM   629  O O     . LEU A 1 116 ? 107.751 109.031 139.996 1.00 31.11  ? 91  LEU R O     1 
ATOM   630  C CB    . LEU A 1 116 ? 106.464 107.451 142.624 1.00 31.11  ? 91  LEU R CB    1 
ATOM   631  C CG    . LEU A 1 116 ? 105.809 107.646 143.992 1.00 31.11  ? 91  LEU R CG    1 
ATOM   632  C CD1   . LEU A 1 116 ? 106.258 106.558 144.950 1.00 31.11  ? 91  LEU R CD1   1 
ATOM   633  C CD2   . LEU A 1 116 ? 106.120 109.019 144.560 1.00 31.11  ? 91  LEU R CD2   1 
ATOM   634  N N     . ILE A 1 117 ? 106.589 107.172 139.494 1.00 30.96  ? 92  ILE R N     1 
ATOM   635  C CA    . ILE A 1 117 ? 107.408 106.922 138.310 1.00 30.96  ? 92  ILE R CA    1 
ATOM   636  C C     . ILE A 1 117 ? 107.279 108.081 137.332 1.00 30.96  ? 92  ILE R C     1 
ATOM   637  O O     . ILE A 1 117 ? 108.275 108.560 136.783 1.00 30.96  ? 92  ILE R O     1 
ATOM   638  C CB    . ILE A 1 117 ? 107.046 105.578 137.644 1.00 30.96  ? 92  ILE R CB    1 
ATOM   639  C CG1   . ILE A 1 117 ? 105.576 105.531 137.238 1.00 30.96  ? 92  ILE R CG1   1 
ATOM   640  C CG2   . ILE A 1 117 ? 107.384 104.409 138.554 1.00 30.96  ? 92  ILE R CG2   1 
ATOM   641  C CD1   . ILE A 1 117 ? 105.216 104.342 136.375 1.00 30.96  ? 92  ILE R CD1   1 
ATOM   642  N N     . PHE A 1 118 ? 106.055 108.567 137.110 1.00 31.03  ? 93  PHE R N     1 
ATOM   643  C CA    . PHE A 1 118 ? 105.897 109.616 136.106 1.00 31.03  ? 93  PHE R CA    1 
ATOM   644  C C     . PHE A 1 118 ? 106.504 110.940 136.566 1.00 31.03  ? 93  PHE R C     1 
ATOM   645  O O     . PHE A 1 118 ? 107.176 111.624 135.776 1.00 31.03  ? 93  PHE R O     1 
ATOM   646  C CB    . PHE A 1 118 ? 104.421 109.782 135.751 1.00 31.03  ? 93  PHE R CB    1 
ATOM   647  C CG    . PHE A 1 118 ? 103.827 108.575 135.080 1.00 31.03  ? 93  PHE R CG    1 
ATOM   648  C CD1   . PHE A 1 118 ? 104.445 108.005 133.979 1.00 31.03  ? 93  PHE R CD1   1 
ATOM   649  C CD2   . PHE A 1 118 ? 102.648 108.016 135.542 1.00 31.03  ? 93  PHE R CD2   1 
ATOM   650  C CE1   . PHE A 1 118 ? 103.904 106.898 133.358 1.00 31.03  ? 93  PHE R CE1   1 
ATOM   651  C CE2   . PHE A 1 118 ? 102.102 106.907 134.923 1.00 31.03  ? 93  PHE R CE2   1 
ATOM   652  C CZ    . PHE A 1 118 ? 102.731 106.349 133.830 1.00 31.03  ? 93  PHE R CZ    1 
ATOM   653  N N     . THR A 1 119 ? 106.302 111.318 137.831 1.00 28.58  ? 94  THR R N     1 
ATOM   654  C CA    . THR A 1 119 ? 106.907 112.557 138.309 1.00 28.58  ? 94  THR R CA    1 
ATOM   655  C C     . THR A 1 119 ? 108.432 112.477 138.299 1.00 28.58  ? 94  THR R C     1 
ATOM   656  O O     . THR A 1 119 ? 109.108 113.431 137.883 1.00 28.58  ? 94  THR R O     1 
ATOM   657  C CB    . THR A 1 119 ? 106.390 112.885 139.709 1.00 28.58  ? 94  THR R CB    1 
ATOM   658  O OG1   . THR A 1 119 ? 106.613 111.771 140.580 1.00 28.58  ? 94  THR R OG1   1 
ATOM   659  C CG2   . THR A 1 119 ? 104.902 113.201 139.666 1.00 28.58  ? 94  THR R CG2   1 
ATOM   660  N N     . HIS A 1 120 ? 108.997 111.350 138.741 1.00 26.87  ? 95  HIS R N     1 
ATOM   661  C CA    . HIS A 1 120 ? 110.443 111.197 138.689 1.00 26.87  ? 95  HIS R CA    1 
ATOM   662  C C     . HIS A 1 120 ? 110.949 111.181 137.254 1.00 26.87  ? 95  HIS R C     1 
ATOM   663  O O     . HIS A 1 120 ? 112.069 111.625 136.994 1.00 26.87  ? 95  HIS R O     1 
ATOM   664  C CB    . HIS A 1 120 ? 110.863 109.921 139.417 1.00 26.87  ? 95  HIS R CB    1 
ATOM   665  C CG    . HIS A 1 120 ? 110.783 110.025 140.908 1.00 26.87  ? 95  HIS R CG    1 
ATOM   666  N ND1   . HIS A 1 120 ? 109.697 109.578 141.627 1.00 26.87  ? 95  HIS R ND1   1 
ATOM   667  C CD2   . HIS A 1 120 ? 111.652 110.532 141.814 1.00 26.87  ? 95  HIS R CD2   1 
ATOM   668  C CE1   . HIS A 1 120 ? 109.902 109.800 142.913 1.00 26.87  ? 95  HIS R CE1   1 
ATOM   669  N NE2   . HIS A 1 120 ? 111.080 110.379 143.053 1.00 26.87  ? 95  HIS R NE2   1 
ATOM   670  N N     . ALA A 1 121 ? 110.145 110.686 136.312 1.00 27.68  ? 96  ALA R N     1 
ATOM   671  C CA    . ALA A 1 121 ? 110.535 110.737 134.908 1.00 27.68  ? 96  ALA R CA    1 
ATOM   672  C C     . ALA A 1 121 ? 110.628 112.176 134.423 1.00 27.68  ? 96  ALA R C     1 
ATOM   673  O O     . ALA A 1 121 ? 111.561 112.541 133.700 1.00 27.68  ? 96  ALA R O     1 
ATOM   674  C CB    . ALA A 1 121 ? 109.542 109.945 134.059 1.00 27.68  ? 96  ALA R CB    1 
ATOM   675  N N     . SER A 1 122 ? 109.662 113.011 134.810 1.00 26.09  ? 97  SER R N     1 
ATOM   676  C CA    . SER A 1 122 ? 109.734 114.425 134.444 1.00 26.09  ? 97  SER R CA    1 
ATOM   677  C C     . SER A 1 122 ? 110.983 115.078 135.032 1.00 26.09  ? 97  SER R C     1 
ATOM   678  O O     . SER A 1 122 ? 111.698 115.830 134.350 1.00 26.09  ? 97  SER R O     1 
ATOM   679  C CB    . SER A 1 122 ? 108.474 115.151 134.916 1.00 26.09  ? 97  SER R CB    1 
ATOM   680  O OG    . SER A 1 122 ? 108.404 115.179 136.330 1.00 26.09  ? 97  SER R OG    1 
ATOM   681  N N     . ILE A 1 123 ? 111.266 114.792 136.304 1.00 24.82  ? 98  ILE R N     1 
ATOM   682  C CA    . ILE A 1 123 ? 112.447 115.371 136.944 1.00 24.82  ? 98  ILE R CA    1 
ATOM   683  C C     . ILE A 1 123 ? 113.718 114.905 136.243 1.00 24.82  ? 98  ILE R C     1 
ATOM   684  O O     . ILE A 1 123 ? 114.659 115.684 136.036 1.00 24.82  ? 98  ILE R O     1 
ATOM   685  C CB    . ILE A 1 123 ? 112.467 115.023 138.443 1.00 24.82  ? 98  ILE R CB    1 
ATOM   686  C CG1   . ILE A 1 123 ? 111.350 115.769 139.174 1.00 24.82  ? 98  ILE R CG1   1 
ATOM   687  C CG2   . ILE A 1 123 ? 113.814 115.370 139.052 1.00 24.82  ? 98  ILE R CG2   1 
ATOM   688  C CD1   . ILE A 1 123 ? 110.785 115.014 140.349 1.00 24.82  ? 98  ILE R CD1   1 
ATOM   689  N N     . MET A 1 124 ? 113.771 113.624 135.875 1.00 23.59  ? 99  MET R N     1 
ATOM   690  C CA    . MET A 1 124 ? 114.942 113.093 135.188 1.00 23.59  ? 99  MET R CA    1 
ATOM   691  C C     . MET A 1 124 ? 115.107 113.724 133.813 1.00 23.59  ? 99  MET R C     1 
ATOM   692  O O     . MET A 1 124 ? 116.233 113.951 133.362 1.00 23.59  ? 99  MET R O     1 
ATOM   693  C CB    . MET A 1 124 ? 114.831 111.574 135.071 1.00 23.59  ? 99  MET R CB    1 
ATOM   694  C CG    . MET A 1 124 ? 115.175 110.837 136.352 1.00 23.59  ? 99  MET R CG    1 
ATOM   695  S SD    . MET A 1 124 ? 116.942 110.828 136.693 1.00 23.59  ? 99  MET R SD    1 
ATOM   696  C CE    . MET A 1 124 ? 116.958 111.490 138.355 1.00 23.59  ? 99  MET R CE    1 
ATOM   697  N N     . SER A 1 125 ? 113.999 114.002 133.125 1.00 23.82  ? 100 SER R N     1 
ATOM   698  C CA    . SER A 1 125 ? 114.087 114.698 131.845 1.00 23.82  ? 100 SER R CA    1 
ATOM   699  C C     . SER A 1 125 ? 114.672 116.093 132.023 1.00 23.82  ? 100 SER R C     1 
ATOM   700  O O     . SER A 1 125 ? 115.507 116.535 131.221 1.00 23.82  ? 100 SER R O     1 
ATOM   701  C CB    . SER A 1 125 ? 112.708 114.776 131.196 1.00 23.82  ? 100 SER R CB    1 
ATOM   702  O OG    . SER A 1 125 ? 112.116 113.493 131.105 1.00 23.82  ? 100 SER R OG    1 
ATOM   703  N N     . LEU A 1 126 ? 114.242 116.806 133.066 1.00 23.99  ? 101 LEU R N     1 
ATOM   704  C CA    . LEU A 1 126 ? 114.827 118.117 133.341 1.00 23.99  ? 101 LEU R CA    1 
ATOM   705  C C     . LEU A 1 126 ? 116.327 118.002 133.595 1.00 23.99  ? 101 LEU R C     1 
ATOM   706  O O     . LEU A 1 126 ? 117.127 118.792 133.072 1.00 23.99  ? 101 LEU R O     1 
ATOM   707  C CB    . LEU A 1 126 ? 114.131 118.762 134.540 1.00 23.99  ? 101 LEU R CB    1 
ATOM   708  C CG    . LEU A 1 126 ? 112.665 119.138 134.329 1.00 23.99  ? 101 LEU R CG    1 
ATOM   709  C CD1   . LEU A 1 126 ? 111.923 119.218 135.651 1.00 23.99  ? 101 LEU R CD1   1 
ATOM   710  C CD2   . LEU A 1 126 ? 112.573 120.457 133.595 1.00 23.99  ? 101 LEU R CD2   1 
ATOM   711  N N     . LEU A 1 127 ? 116.726 117.013 134.396 1.00 21.63  ? 102 LEU R N     1 
ATOM   712  C CA    . LEU A 1 127 ? 118.145 116.815 134.668 1.00 21.63  ? 102 LEU R CA    1 
ATOM   713  C C     . LEU A 1 127 ? 118.911 116.499 133.389 1.00 21.63  ? 102 LEU R C     1 
ATOM   714  O O     . LEU A 1 127 ? 120.043 116.961 133.201 1.00 21.63  ? 102 LEU R O     1 
ATOM   715  C CB    . LEU A 1 127 ? 118.328 115.697 135.693 1.00 21.63  ? 102 LEU R CB    1 
ATOM   716  C CG    . LEU A 1 127 ? 119.770 115.273 135.972 1.00 21.63  ? 102 LEU R CG    1 
ATOM   717  C CD1   . LEU A 1 127 ? 120.617 116.471 136.368 1.00 21.63  ? 102 LEU R CD1   1 
ATOM   718  C CD2   . LEU A 1 127 ? 119.808 114.207 137.051 1.00 21.63  ? 102 LEU R CD2   1 
ATOM   719  N N     . ALA A 1 128 ? 118.315 115.701 132.503 1.00 22.70  ? 103 ALA R N     1 
ATOM   720  C CA    . ALA A 1 128 ? 118.969 115.359 131.245 1.00 22.70  ? 103 ALA R CA    1 
ATOM   721  C C     . ALA A 1 128 ? 119.164 116.595 130.379 1.00 22.70  ? 103 ALA R C     1 
ATOM   722  O O     . ALA A 1 128 ? 120.214 116.763 129.749 1.00 22.70  ? 103 ALA R O     1 
ATOM   723  C CB    . ALA A 1 128 ? 118.153 114.304 130.501 1.00 22.70  ? 103 ALA R CB    1 
ATOM   724  N N     . ILE A 1 129 ? 118.155 117.467 130.323 1.00 22.97  ? 104 ILE R N     1 
ATOM   725  C CA    . ILE A 1 129 ? 118.300 118.713 129.571 1.00 22.97  ? 104 ILE R CA    1 
ATOM   726  C C     . ILE A 1 129 ? 119.446 119.538 130.142 1.00 22.97  ? 104 ILE R C     1 
ATOM   727  O O     . ILE A 1 129 ? 120.272 120.096 129.405 1.00 22.97  ? 104 ILE R O     1 
ATOM   728  C CB    . ILE A 1 129 ? 116.982 119.506 129.578 1.00 22.97  ? 104 ILE R CB    1 
ATOM   729  C CG1   . ILE A 1 129 ? 115.948 118.827 128.683 1.00 22.97  ? 104 ILE R CG1   1 
ATOM   730  C CG2   . ILE A 1 129 ? 117.216 120.933 129.115 1.00 22.97  ? 104 ILE R CG2   1 
ATOM   731  C CD1   . ILE A 1 129 ? 114.528 119.106 129.088 1.00 22.97  ? 104 ILE R CD1   1 
ATOM   732  N N     . ALA A 1 130 ? 119.508 119.633 131.471 1.00 21.95  ? 105 ALA R N     1 
ATOM   733  C CA    . ALA A 1 130 ? 120.579 120.402 132.099 1.00 21.95  ? 105 ALA R CA    1 
ATOM   734  C C     . ALA A 1 130 ? 121.945 119.829 131.741 1.00 21.95  ? 105 ALA R C     1 
ATOM   735  O O     . ALA A 1 130 ? 122.879 120.571 131.408 1.00 21.95  ? 105 ALA R O     1 
ATOM   736  C CB    . ALA A 1 130 ? 120.385 120.428 133.614 1.00 21.95  ? 105 ALA R CB    1 
ATOM   737  N N     . VAL A 1 131 ? 122.080 118.503 131.798 1.00 23.18  ? 106 VAL R N     1 
ATOM   738  C CA    . VAL A 1 131 ? 123.368 117.876 131.509 1.00 23.18  ? 106 VAL R CA    1 
ATOM   739  C C     . VAL A 1 131 ? 123.739 118.067 130.044 1.00 23.18  ? 106 VAL R C     1 
ATOM   740  O O     . VAL A 1 131 ? 124.913 118.260 129.706 1.00 23.18  ? 106 VAL R O     1 
ATOM   741  C CB    . VAL A 1 131 ? 123.339 116.386 131.895 1.00 23.18  ? 106 VAL R CB    1 
ATOM   742  C CG1   . VAL A 1 131 ? 124.640 115.709 131.490 1.00 23.18  ? 106 VAL R CG1   1 
ATOM   743  C CG2   . VAL A 1 131 ? 123.107 116.229 133.388 1.00 23.18  ? 106 VAL R CG2   1 
ATOM   744  N N     . ASP A 1 132 ? 122.752 118.002 129.150 1.00 24.72  ? 107 ASP R N     1 
ATOM   745  C CA    . ASP A 1 132 ? 123.018 118.225 127.733 1.00 24.72  ? 107 ASP R CA    1 
ATOM   746  C C     . ASP A 1 132 ? 123.531 119.639 127.495 1.00 24.72  ? 107 ASP R C     1 
ATOM   747  O O     . ASP A 1 132 ? 124.489 119.853 126.741 1.00 24.72  ? 107 ASP R O     1 
ATOM   748  C CB    . ASP A 1 132 ? 121.750 117.966 126.921 1.00 24.72  ? 107 ASP R CB    1 
ATOM   749  C CG    . ASP A 1 132 ? 121.818 118.560 125.531 1.00 24.72  ? 107 ASP R CG    1 
ATOM   750  O OD1   . ASP A 1 132 ? 122.884 118.454 124.890 1.00 24.72  ? 107 ASP R OD1   1 
ATOM   751  O OD2   . ASP A 1 132 ? 120.808 119.139 125.080 1.00 24.72  ? 107 ASP R OD2   1 
ATOM   752  N N     . ARG A 1 133 ? 122.895 120.626 128.131 1.00 24.43  ? 108 ARG R N     1 
ATOM   753  C CA    . ARG A 1 133 ? 123.371 122.000 128.007 1.00 24.43  ? 108 ARG R CA    1 
ATOM   754  C C     . ARG A 1 133 ? 124.788 122.134 128.546 1.00 24.43  ? 108 ARG R C     1 
ATOM   755  O O     . ARG A 1 133 ? 125.630 122.824 127.956 1.00 24.43  ? 108 ARG R O     1 
ATOM   756  C CB    . ARG A 1 133 ? 122.428 122.952 128.742 1.00 24.43  ? 108 ARG R CB    1 
ATOM   757  C CG    . ARG A 1 133 ? 121.067 123.095 128.094 1.00 24.43  ? 108 ARG R CG    1 
ATOM   758  C CD    . ARG A 1 133 ? 120.169 124.017 128.896 1.00 24.43  ? 108 ARG R CD    1 
ATOM   759  N NE    . ARG A 1 133 ? 118.942 124.342 128.179 1.00 24.43  ? 108 ARG R NE    1 
ATOM   760  C CZ    . ARG A 1 133 ? 117.967 125.096 128.665 1.00 24.43  ? 108 ARG R CZ    1 
ATOM   761  N NH1   . ARG A 1 133 ? 118.035 125.619 129.879 1.00 24.43  ? 108 ARG R NH1   1 
ATOM   762  N NH2   . ARG A 1 133 ? 116.895 125.333 127.915 1.00 24.43  ? 108 ARG R NH2   1 
ATOM   763  N N     . TYR A 1 134 ? 125.070 121.478 129.673 1.00 25.37  ? 109 TYR R N     1 
ATOM   764  C CA    . TYR A 1 134 ? 126.414 121.521 130.238 1.00 25.37  ? 109 TYR R CA    1 
ATOM   765  C C     . TYR A 1 134 ? 127.431 120.962 129.255 1.00 25.37  ? 109 TYR R C     1 
ATOM   766  O O     . TYR A 1 134 ? 128.506 121.538 129.054 1.00 25.37  ? 109 TYR R O     1 
ATOM   767  C CB    . TYR A 1 134 ? 126.454 120.730 131.542 1.00 25.37  ? 109 TYR R CB    1 
ATOM   768  C CG    . TYR A 1 134 ? 127.758 120.848 132.295 1.00 25.37  ? 109 TYR R CG    1 
ATOM   769  C CD1   . TYR A 1 134 ? 128.264 122.089 132.655 1.00 25.37  ? 109 TYR R CD1   1 
ATOM   770  C CD2   . TYR A 1 134 ? 128.478 119.719 132.654 1.00 25.37  ? 109 TYR R CD2   1 
ATOM   771  C CE1   . TYR A 1 134 ? 129.451 122.201 133.346 1.00 25.37  ? 109 TYR R CE1   1 
ATOM   772  C CE2   . TYR A 1 134 ? 129.666 119.821 133.344 1.00 25.37  ? 109 TYR R CE2   1 
ATOM   773  C CZ    . TYR A 1 134 ? 130.148 121.063 133.688 1.00 25.37  ? 109 TYR R CZ    1 
ATOM   774  O OH    . TYR A 1 134 ? 131.333 121.166 134.378 1.00 25.37  ? 109 TYR R OH    1 
ATOM   775  N N     . LEU A 1 135 ? 127.107 119.824 128.640 1.00 25.16  ? 110 LEU R N     1 
ATOM   776  C CA    . LEU A 1 135 ? 128.021 119.214 127.683 1.00 25.16  ? 110 LEU R CA    1 
ATOM   777  C C     . LEU A 1 135 ? 128.254 120.138 126.496 1.00 25.16  ? 110 LEU R C     1 
ATOM   778  O O     . LEU A 1 135 ? 129.395 120.342 126.068 1.00 25.16  ? 110 LEU R O     1 
ATOM   779  C CB    . LEU A 1 135 ? 127.468 117.867 127.219 1.00 25.16  ? 110 LEU R CB    1 
ATOM   780  C CG    . LEU A 1 135 ? 127.574 116.709 128.214 1.00 25.16  ? 110 LEU R CG    1 
ATOM   781  C CD1   . LEU A 1 135 ? 126.939 115.458 127.630 1.00 25.16  ? 110 LEU R CD1   1 
ATOM   782  C CD2   . LEU A 1 135 ? 129.021 116.444 128.601 1.00 25.16  ? 110 LEU R CD2   1 
ATOM   783  N N     . ARG A 1 136 ? 127.183 120.722 125.962 1.00 26.66  ? 111 ARG R N     1 
ATOM   784  C CA    . ARG A 1 136 ? 127.320 121.642 124.840 1.00 26.66  ? 111 ARG R CA    1 
ATOM   785  C C     . ARG A 1 136 ? 128.256 122.785 125.201 1.00 26.66  ? 111 ARG R C     1 
ATOM   786  O O     . ARG A 1 136 ? 129.141 123.144 124.418 1.00 26.66  ? 111 ARG R O     1 
ATOM   787  C CB    . ARG A 1 136 ? 125.961 122.201 124.420 1.00 26.66  ? 111 ARG R CB    1 
ATOM   788  C CG    . ARG A 1 136 ? 125.171 121.281 123.523 1.00 26.66  ? 111 ARG R CG    1 
ATOM   789  C CD    . ARG A 1 136 ? 123.725 121.706 123.454 1.00 26.66  ? 111 ARG R CD    1 
ATOM   790  N NE    . ARG A 1 136 ? 122.919 120.793 122.651 1.00 26.66  ? 111 ARG R NE    1 
ATOM   791  C CZ    . ARG A 1 136 ? 122.284 121.120 121.532 1.00 26.66  ? 111 ARG R CZ    1 
ATOM   792  N NH1   . ARG A 1 136 ? 122.352 122.340 121.023 1.00 26.66  ? 111 ARG R NH1   1 
ATOM   793  N NH2   . ARG A 1 136 ? 121.565 120.196 120.901 1.00 26.66  ? 111 ARG R NH2   1 
ATOM   794  N N     . VAL A 1 137 ? 128.067 123.365 126.387 1.00 27.17  ? 112 VAL R N     1 
ATOM   795  C CA    . VAL A 1 137 ? 128.885 124.508 126.788 1.00 27.17  ? 112 VAL R CA    1 
ATOM   796  C C     . VAL A 1 137 ? 130.342 124.092 126.949 1.00 27.17  ? 112 VAL R C     1 
ATOM   797  O O     . VAL A 1 137 ? 131.260 124.790 126.501 1.00 27.17  ? 112 VAL R O     1 
ATOM   798  C CB    . VAL A 1 137 ? 128.330 125.135 128.080 1.00 27.17  ? 112 VAL R CB    1 
ATOM   799  C CG1   . VAL A 1 137 ? 129.388 125.992 128.762 1.00 27.17  ? 112 VAL R CG1   1 
ATOM   800  C CG2   . VAL A 1 137 ? 127.089 125.956 127.772 1.00 27.17  ? 112 VAL R CG2   1 
ATOM   801  N N     . LYS A 1 138 ? 130.578 122.945 127.588 1.00 26.96  ? 113 LYS R N     1 
ATOM   802  C CA    . LYS A 1 138 ? 131.926 122.582 128.010 1.00 26.96  ? 113 LYS R CA    1 
ATOM   803  C C     . LYS A 1 138 ? 132.682 121.727 126.999 1.00 26.96  ? 113 LYS R C     1 
ATOM   804  O O     . LYS A 1 138 ? 133.917 121.728 127.025 1.00 26.96  ? 113 LYS R O     1 
ATOM   805  C CB    . LYS A 1 138 ? 131.866 121.847 129.351 1.00 26.96  ? 113 LYS R CB    1 
ATOM   806  C CG    . LYS A 1 138 ? 133.219 121.301 129.812 1.00 26.96  ? 113 LYS R CG    1 
ATOM   807  C CD    . LYS A 1 138 ? 133.388 121.168 131.335 1.00 26.96  ? 113 LYS R CD    1 
ATOM   808  C CE    . LYS A 1 138 ? 132.996 122.414 132.129 1.00 26.96  ? 113 LYS R CE    1 
ATOM   809  N NZ    . LYS A 1 138 ? 133.914 123.555 131.865 1.00 26.96  ? 113 LYS R NZ    1 
ATOM   810  N N     . LEU A 1 139 ? 131.994 121.003 126.116 1.00 26.21  ? 114 LEU R N     1 
ATOM   811  C CA    . LEU A 1 139 ? 132.676 120.178 125.125 1.00 26.21  ? 114 LEU R CA    1 
ATOM   812  C C     . LEU A 1 139 ? 133.089 120.958 123.886 1.00 26.21  ? 114 LEU R C     1 
ATOM   813  O O     . LEU A 1 139 ? 134.051 120.569 123.216 1.00 26.21  ? 114 LEU R O     1 
ATOM   814  C CB    . LEU A 1 139 ? 131.786 119.002 124.702 1.00 26.21  ? 114 LEU R CB    1 
ATOM   815  C CG    . LEU A 1 139 ? 131.791 117.754 125.594 1.00 26.21  ? 114 LEU R CG    1 
ATOM   816  C CD1   . LEU A 1 139 ? 130.987 116.639 124.945 1.00 26.21  ? 114 LEU R CD1   1 
ATOM   817  C CD2   . LEU A 1 139 ? 133.205 117.276 125.895 1.00 26.21  ? 114 LEU R CD2   1 
ATOM   818  N N     . THR A 1 140 ? 132.389 122.045 123.569 1.00 27.72  ? 115 THR R N     1 
ATOM   819  C CA    . THR A 1 140 ? 132.771 122.966 122.495 1.00 27.72  ? 115 THR R CA    1 
ATOM   820  C C     . THR A 1 140 ? 132.699 122.218 121.169 1.00 27.72  ? 115 THR R C     1 
ATOM   821  O O     . THR A 1 140 ? 131.614 121.718 120.823 1.00 27.72  ? 115 THR R O     1 
ATOM   822  C CB    . THR A 1 140 ? 134.133 123.577 122.833 1.00 27.72  ? 115 THR R CB    1 
ATOM   823  O OG1   . THR A 1 140 ? 135.158 122.587 122.673 1.00 27.72  ? 115 THR R OG1   1 
ATOM   824  C CG2   . THR A 1 140 ? 134.151 124.099 124.262 1.00 27.72  ? 115 THR R CG2   1 
ATOM   825  N N     . VAL A 1 141 ? 133.788 122.114 120.406 1.00 26.14  ? 116 VAL R N     1 
ATOM   826  C CA    . VAL A 1 141 ? 133.712 121.544 119.064 1.00 26.14  ? 116 VAL R CA    1 
ATOM   827  C C     . VAL A 1 141 ? 133.455 120.043 119.125 1.00 26.14  ? 116 VAL R C     1 
ATOM   828  O O     . VAL A 1 141 ? 132.704 119.496 118.307 1.00 26.14  ? 116 VAL R O     1 
ATOM   829  C CB    . VAL A 1 141 ? 134.995 121.871 118.279 1.00 26.14  ? 116 VAL R CB    1 
ATOM   830  C CG1   . VAL A 1 141 ? 135.248 123.369 118.288 1.00 26.14  ? 116 VAL R CG1   1 
ATOM   831  C CG2   . VAL A 1 141 ? 136.189 121.124 118.857 1.00 26.14  ? 116 VAL R CG2   1 
ATOM   832  N N     . ARG A 1 142 ? 134.065 119.353 120.086 1.00 27.54  ? 117 ARG R N     1 
ATOM   833  C CA    . ARG A 1 142 ? 133.977 117.899 120.168 1.00 27.54  ? 117 ARG R CA    1 
ATOM   834  C C     . ARG A 1 142 ? 132.609 117.410 120.627 1.00 27.54  ? 117 ARG R C     1 
ATOM   835  O O     . ARG A 1 142 ? 132.385 116.196 120.657 1.00 27.54  ? 117 ARG R O     1 
ATOM   836  C CB    . ARG A 1 142 ? 135.054 117.351 121.108 1.00 27.54  ? 117 ARG R CB    1 
ATOM   837  C CG    . ARG A 1 142 ? 136.384 118.087 121.048 1.00 27.54  ? 117 ARG R CG    1 
ATOM   838  C CD    . ARG A 1 142 ? 137.475 117.316 121.776 1.00 27.54  ? 117 ARG R CD    1 
ATOM   839  N NE    . ARG A 1 142 ? 137.150 117.090 123.180 1.00 27.54  ? 117 ARG R NE    1 
ATOM   840  C CZ    . ARG A 1 142 ? 137.119 118.038 124.108 1.00 27.54  ? 117 ARG R CZ    1 
ATOM   841  N NH1   . ARG A 1 142 ? 137.401 119.298 123.820 1.00 27.54  ? 117 ARG R NH1   1 
ATOM   842  N NH2   . ARG A 1 142 ? 136.799 117.712 125.357 1.00 27.54  ? 117 ARG R NH2   1 
ATOM   843  N N     . TYR A 1 143 ? 131.695 118.315 120.982 1.00 26.39  ? 118 TYR R N     1 
ATOM   844  C CA    . TYR A 1 143 ? 130.382 117.893 121.458 1.00 26.39  ? 118 TYR R CA    1 
ATOM   845  C C     . TYR A 1 143 ? 129.704 116.970 120.453 1.00 26.39  ? 118 TYR R C     1 
ATOM   846  O O     . TYR A 1 143 ? 129.293 115.855 120.798 1.00 26.39  ? 118 TYR R O     1 
ATOM   847  C CB    . TYR A 1 143 ? 129.513 119.120 121.738 1.00 26.39  ? 118 TYR R CB    1 
ATOM   848  C CG    . TYR A 1 143 ? 128.041 118.811 121.892 1.00 26.39  ? 118 TYR R CG    1 
ATOM   849  C CD1   . TYR A 1 143 ? 127.559 118.180 123.029 1.00 26.39  ? 118 TYR R CD1   1 
ATOM   850  C CD2   . TYR A 1 143 ? 127.134 119.153 120.899 1.00 26.39  ? 118 TYR R CD2   1 
ATOM   851  C CE1   . TYR A 1 143 ? 126.216 117.897 123.172 1.00 26.39  ? 118 TYR R CE1   1 
ATOM   852  C CE2   . TYR A 1 143 ? 125.790 118.874 121.034 1.00 26.39  ? 118 TYR R CE2   1 
ATOM   853  C CZ    . TYR A 1 143 ? 125.336 118.245 122.171 1.00 26.39  ? 118 TYR R CZ    1 
ATOM   854  O OH    . TYR A 1 143 ? 123.997 117.966 122.309 1.00 26.39  ? 118 TYR R OH    1 
ATOM   855  N N     . ARG A 1 144 ? 129.603 117.402 119.194 1.00 27.49  ? 119 ARG R N     1 
ATOM   856  C CA    . ARG A 1 144 ? 128.973 116.567 118.180 1.00 27.49  ? 119 ARG R CA    1 
ATOM   857  C C     . ARG A 1 144 ? 129.730 115.266 117.958 1.00 27.49  ? 119 ARG R C     1 
ATOM   858  O O     . ARG A 1 144 ? 129.132 114.284 117.505 1.00 27.49  ? 119 ARG R O     1 
ATOM   859  C CB    . ARG A 1 144 ? 128.860 117.329 116.859 1.00 27.49  ? 119 ARG R CB    1 
ATOM   860  C CG    . ARG A 1 144 ? 128.085 118.644 116.957 1.00 27.49  ? 119 ARG R CG    1 
ATOM   861  C CD    . ARG A 1 144 ? 126.569 118.472 116.824 1.00 27.49  ? 119 ARG R CD    1 
ATOM   862  N NE    . ARG A 1 144 ? 126.179 117.359 115.967 1.00 27.49  ? 119 ARG R NE    1 
ATOM   863  C CZ    . ARG A 1 144 ? 126.167 117.398 114.641 1.00 27.49  ? 119 ARG R CZ    1 
ATOM   864  N NH1   . ARG A 1 144 ? 126.522 118.486 113.977 1.00 27.49  ? 119 ARG R NH1   1 
ATOM   865  N NH2   . ARG A 1 144 ? 125.788 116.318 113.964 1.00 27.49  ? 119 ARG R NH2   1 
ATOM   866  N N     . ARG A 1 145 ? 131.027 115.235 118.268 1.00 27.35  ? 120 ARG R N     1 
ATOM   867  C CA    . ARG A 1 145 ? 131.808 114.014 118.129 1.00 27.35  ? 120 ARG R CA    1 
ATOM   868  C C     . ARG A 1 145 ? 131.643 113.075 119.316 1.00 27.35  ? 120 ARG R C     1 
ATOM   869  O O     . ARG A 1 145 ? 132.072 111.919 119.236 1.00 27.35  ? 120 ARG R O     1 
ATOM   870  C CB    . ARG A 1 145 ? 133.289 114.358 117.954 1.00 27.35  ? 120 ARG R CB    1 
ATOM   871  C CG    . ARG A 1 145 ? 134.128 113.214 117.418 1.00 27.35  ? 120 ARG R CG    1 
ATOM   872  C CD    . ARG A 1 145 ? 135.591 113.601 117.296 1.00 27.35  ? 120 ARG R CD    1 
ATOM   873  N NE    . ARG A 1 145 ? 136.356 112.593 116.571 1.00 27.35  ? 120 ARG R NE    1 
ATOM   874  C CZ    . ARG A 1 145 ? 137.661 112.657 116.344 1.00 27.35  ? 120 ARG R CZ    1 
ATOM   875  N NH1   . ARG A 1 145 ? 138.388 113.676 116.772 1.00 27.35  ? 120 ARG R NH1   1 
ATOM   876  N NH2   . ARG A 1 145 ? 138.251 111.675 115.671 1.00 27.35  ? 120 ARG R NH2   1 
ATOM   877  N N     . VAL A 1 146 ? 131.034 113.538 120.407 1.00 26.08  ? 121 VAL R N     1 
ATOM   878  C CA    . VAL A 1 146 ? 130.877 112.721 121.605 1.00 26.08  ? 121 VAL R CA    1 
ATOM   879  C C     . VAL A 1 146 ? 129.406 112.376 121.792 1.00 26.08  ? 121 VAL R C     1 
ATOM   880  O O     . VAL A 1 146 ? 129.070 111.337 122.369 1.00 26.08  ? 121 VAL R O     1 
ATOM   881  C CB    . VAL A 1 146 ? 131.440 113.443 122.843 1.00 26.08  ? 121 VAL R CB    1 
ATOM   882  C CG1   . VAL A 1 146 ? 130.995 112.746 124.120 1.00 26.08  ? 121 VAL R CG1   1 
ATOM   883  C CG2   . VAL A 1 146 ? 132.957 113.513 122.771 1.00 26.08  ? 121 VAL R CG2   1 
ATOM   884  N N     . THR A 1 147 ? 128.522 113.237 121.297 1.00 26.91  ? 122 THR R N     1 
ATOM   885  C CA    . THR A 1 147 ? 127.081 113.072 121.469 1.00 26.91  ? 122 THR R CA    1 
ATOM   886  C C     . THR A 1 147 ? 126.487 112.585 120.152 1.00 26.91  ? 122 THR R C     1 
ATOM   887  O O     . THR A 1 147 ? 126.191 113.382 119.257 1.00 26.91  ? 122 THR R O     1 
ATOM   888  C CB    . THR A 1 147 ? 126.440 114.379 121.923 1.00 26.91  ? 122 THR R CB    1 
ATOM   889  O OG1   . THR A 1 147 ? 126.880 114.692 123.251 1.00 26.91  ? 122 THR R OG1   1 
ATOM   890  C CG2   . THR A 1 147 ? 124.923 114.268 121.906 1.00 26.91  ? 122 THR R CG2   1 
ATOM   891  N N     . THR A 1 148 ? 126.312 111.273 120.040 1.00 27.99  ? 123 THR R N     1 
ATOM   892  C CA    . THR A 1 148 ? 125.672 110.652 118.892 1.00 27.99  ? 123 THR R CA    1 
ATOM   893  C C     . THR A 1 148 ? 124.256 110.221 119.258 1.00 27.99  ? 123 THR R C     1 
ATOM   894  O O     . THR A 1 148 ? 123.871 110.185 120.428 1.00 27.99  ? 123 THR R O     1 
ATOM   895  C CB    . THR A 1 148 ? 126.488 109.450 118.403 1.00 27.99  ? 123 THR R CB    1 
ATOM   896  O OG1   . THR A 1 148 ? 126.776 108.580 119.503 1.00 27.99  ? 123 THR R OG1   1 
ATOM   897  C CG2   . THR A 1 148 ? 127.793 109.911 117.778 1.00 27.99  ? 123 THR R CG2   1 
ATOM   898  N N     . GLN A 1 149 ? 123.473 109.887 118.230 1.00 32.38  ? 124 GLN R N     1 
ATOM   899  C CA    . GLN A 1 149 ? 122.078 109.525 118.462 1.00 32.38  ? 124 GLN R CA    1 
ATOM   900  C C     . GLN A 1 149 ? 121.966 108.315 119.380 1.00 32.38  ? 124 GLN R C     1 
ATOM   901  O O     . GLN A 1 149 ? 121.140 108.299 120.302 1.00 32.38  ? 124 GLN R O     1 
ATOM   902  C CB    . GLN A 1 149 ? 121.379 109.254 117.130 1.00 32.38  ? 124 GLN R CB    1 
ATOM   903  C CG    . GLN A 1 149 ? 120.895 110.505 116.427 1.00 32.38  ? 124 GLN R CG    1 
ATOM   904  C CD    . GLN A 1 149 ? 120.008 110.189 115.244 1.00 32.38  ? 124 GLN R CD    1 
ATOM   905  O OE1   . GLN A 1 149 ? 119.682 109.030 114.990 1.00 32.38  ? 124 GLN R OE1   1 
ATOM   906  N NE2   . GLN A 1 149 ? 119.609 111.221 114.513 1.00 32.38  ? 124 GLN R NE2   1 
ATOM   907  N N     . ARG A 1 150 ? 122.802 107.300 119.157 1.00 34.75  ? 125 ARG R N     1 
ATOM   908  C CA    . ARG A 1 150 ? 122.720 106.080 119.951 1.00 34.75  ? 125 ARG R CA    1 
ATOM   909  C C     . ARG A 1 150 ? 122.892 106.387 121.433 1.00 34.75  ? 125 ARG R C     1 
ATOM   910  O O     . ARG A 1 150 ? 122.133 105.898 122.278 1.00 34.75  ? 125 ARG R O     1 
ATOM   911  C CB    . ARG A 1 150 ? 123.779 105.082 119.480 1.00 34.75  ? 125 ARG R CB    1 
ATOM   912  C CG    . ARG A 1 150 ? 123.312 104.160 118.367 1.00 34.75  ? 125 ARG R CG    1 
ATOM   913  C CD    . ARG A 1 150 ? 124.495 103.499 117.678 1.00 34.75  ? 125 ARG R CD    1 
ATOM   914  N NE    . ARG A 1 150 ? 124.124 102.856 116.423 1.00 34.75  ? 125 ARG R NE    1 
ATOM   915  C CZ    . ARG A 1 150 ? 124.991 102.319 115.575 1.00 34.75  ? 125 ARG R CZ    1 
ATOM   916  N NH1   . ARG A 1 150 ? 126.292 102.320 115.821 1.00 34.75  ? 125 ARG R NH1   1 
ATOM   917  N NH2   . ARG A 1 150 ? 124.543 101.768 114.451 1.00 34.75  ? 125 ARG R NH2   1 
ATOM   918  N N     . ARG A 1 151 ? 123.884 107.216 121.766 1.00 27.95  ? 126 ARG R N     1 
ATOM   919  C CA    . ARG A 1 151 ? 124.109 107.563 123.164 1.00 27.95  ? 126 ARG R CA    1 
ATOM   920  C C     . ARG A 1 151 ? 122.952 108.385 123.717 1.00 27.95  ? 126 ARG R C     1 
ATOM   921  O O     . ARG A 1 151 ? 122.633 108.296 124.907 1.00 27.95  ? 126 ARG R O     1 
ATOM   922  C CB    . ARG A 1 151 ? 125.430 108.316 123.309 1.00 27.95  ? 126 ARG R CB    1 
ATOM   923  C CG    . ARG A 1 151 ? 126.617 107.545 122.760 1.00 27.95  ? 126 ARG R CG    1 
ATOM   924  C CD    . ARG A 1 151 ? 127.936 108.022 123.342 1.00 27.95  ? 126 ARG R CD    1 
ATOM   925  N NE    . ARG A 1 151 ? 128.983 108.075 122.327 1.00 27.95  ? 126 ARG R NE    1 
ATOM   926  C CZ    . ARG A 1 151 ? 130.015 107.243 122.249 1.00 27.95  ? 126 ARG R CZ    1 
ATOM   927  N NH1   . ARG A 1 151 ? 130.176 106.250 123.110 1.00 27.95  ? 126 ARG R NH1   1 
ATOM   928  N NH2   . ARG A 1 151 ? 130.907 107.408 121.277 1.00 27.95  ? 126 ARG R NH2   1 
ATOM   929  N N     . ILE A 1 152 ? 122.301 109.181 122.869 1.00 28.41  ? 127 ILE R N     1 
ATOM   930  C CA    . ILE A 1 152 ? 121.159 109.967 123.330 1.00 28.41  ? 127 ILE R CA    1 
ATOM   931  C C     . ILE A 1 152 ? 120.002 109.051 123.711 1.00 28.41  ? 127 ILE R C     1 
ATOM   932  O O     . ILE A 1 152 ? 119.402 109.196 124.783 1.00 28.41  ? 127 ILE R O     1 
ATOM   933  C CB    . ILE A 1 152 ? 120.742 110.989 122.259 1.00 28.41  ? 127 ILE R CB    1 
ATOM   934  C CG1   . ILE A 1 152 ? 121.818 112.064 122.122 1.00 28.41  ? 127 ILE R CG1   1 
ATOM   935  C CG2   . ILE A 1 152 ? 119.407 111.620 122.615 1.00 28.41  ? 127 ILE R CG2   1 
ATOM   936  C CD1   . ILE A 1 152 ? 121.825 112.737 120.784 1.00 28.41  ? 127 ILE R CD1   1 
ATOM   937  N N     . TRP A 1 153 ? 119.663 108.098 122.838 1.00 31.03  ? 128 TRP R N     1 
ATOM   938  C CA    . TRP A 1 153 ? 118.614 107.155 123.211 1.00 31.03  ? 128 TRP R CA    1 
ATOM   939  C C     . TRP A 1 153 ? 119.021 106.272 124.381 1.00 31.03  ? 128 TRP R C     1 
ATOM   940  O O     . TRP A 1 153 ? 118.149 105.850 125.147 1.00 31.03  ? 128 TRP R O     1 
ATOM   941  C CB    . TRP A 1 153 ? 118.200 106.261 122.037 1.00 31.03  ? 128 TRP R CB    1 
ATOM   942  C CG    . TRP A 1 153 ? 117.821 106.983 120.781 1.00 31.03  ? 128 TRP R CG    1 
ATOM   943  C CD1   . TRP A 1 153 ? 118.622 107.247 119.714 1.00 31.03  ? 128 TRP R CD1   1 
ATOM   944  C CD2   . TRP A 1 153 ? 116.541 107.547 120.470 1.00 31.03  ? 128 TRP R CD2   1 
ATOM   945  N NE1   . TRP A 1 153 ? 117.922 107.930 118.749 1.00 31.03  ? 128 TRP R NE1   1 
ATOM   946  C CE2   . TRP A 1 153 ? 116.641 108.129 119.191 1.00 31.03  ? 128 TRP R CE2   1 
ATOM   947  C CE3   . TRP A 1 153 ? 115.319 107.615 121.148 1.00 31.03  ? 128 TRP R CE3   1 
ATOM   948  C CZ2   . TRP A 1 153 ? 115.570 108.768 118.576 1.00 31.03  ? 128 TRP R CZ2   1 
ATOM   949  C CZ3   . TRP A 1 153 ? 114.254 108.250 120.535 1.00 31.03  ? 128 TRP R CZ3   1 
ATOM   950  C CH2   . TRP A 1 153 ? 114.387 108.819 119.261 1.00 31.03  ? 128 TRP R CH2   1 
ATOM   951  N N     . LEU A 1 154 ? 120.312 105.986 124.542 1.00 29.25  ? 129 LEU R N     1 
ATOM   952  C CA    . LEU A 1 154 ? 120.776 105.203 125.677 1.00 29.25  ? 129 LEU R CA    1 
ATOM   953  C C     . LEU A 1 154 ? 120.699 105.967 126.990 1.00 29.25  ? 129 LEU R C     1 
ATOM   954  O O     . LEU A 1 154 ? 120.472 105.351 128.037 1.00 29.25  ? 129 LEU R O     1 
ATOM   955  C CB    . LEU A 1 154 ? 122.219 104.749 125.436 1.00 29.25  ? 129 LEU R CB    1 
ATOM   956  C CG    . LEU A 1 154 ? 122.786 103.717 126.409 1.00 29.25  ? 129 LEU R CG    1 
ATOM   957  C CD1   . LEU A 1 154 ? 123.723 102.774 125.675 1.00 29.25  ? 129 LEU R CD1   1 
ATOM   958  C CD2   . LEU A 1 154 ? 123.507 104.395 127.565 1.00 29.25  ? 129 LEU R CD2   1 
ATOM   959  N N     . ALA A 1 155 ? 120.889 107.285 126.959 1.00 26.45  ? 130 ALA R N     1 
ATOM   960  C CA    . ALA A 1 155 ? 120.726 108.116 128.143 1.00 26.45  ? 130 ALA R CA    1 
ATOM   961  C C     . ALA A 1 155 ? 119.258 108.334 128.485 1.00 26.45  ? 130 ALA R C     1 
ATOM   962  O O     . ALA A 1 155 ? 118.879 108.259 129.658 1.00 26.45  ? 130 ALA R O     1 
ATOM   963  C CB    . ALA A 1 155 ? 121.419 109.464 127.938 1.00 26.45  ? 130 ALA R CB    1 
ATOM   964  N N     . LEU A 1 156 ? 118.420 108.596 127.480 1.00 26.11  ? 131 LEU R N     1 
ATOM   965  C CA    . LEU A 1 156 ? 116.990 108.746 127.734 1.00 26.11  ? 131 LEU R CA    1 
ATOM   966  C C     . LEU A 1 156 ? 116.386 107.452 128.267 1.00 26.11  ? 131 LEU R C     1 
ATOM   967  O O     . LEU A 1 156 ? 115.608 107.467 129.233 1.00 26.11  ? 131 LEU R O     1 
ATOM   968  C CB    . LEU A 1 156 ? 116.278 109.178 126.453 1.00 26.11  ? 131 LEU R CB    1 
ATOM   969  C CG    . LEU A 1 156 ? 116.214 110.679 126.173 1.00 26.11  ? 131 LEU R CG    1 
ATOM   970  C CD1   . LEU A 1 156 ? 117.570 111.229 125.789 1.00 26.11  ? 131 LEU R CD1   1 
ATOM   971  C CD2   . LEU A 1 156 ? 115.216 110.943 125.067 1.00 26.11  ? 131 LEU R CD2   1 
ATOM   972  N N     . GLY A 1 157 ? 116.731 106.323 127.648 1.00 25.12  ? 132 GLY R N     1 
ATOM   973  C CA    . GLY A 1 157 ? 116.245 105.047 128.140 1.00 25.12  ? 132 GLY R CA    1 
ATOM   974  C C     . GLY A 1 157 ? 116.733 104.751 129.543 1.00 25.12  ? 132 GLY R C     1 
ATOM   975  O O     . GLY A 1 157 ? 115.988 104.216 130.367 1.00 25.12  ? 132 GLY R O     1 
ATOM   976  N N     . LEU A 1 158 ? 117.989 105.094 129.836 1.00 25.57  ? 133 LEU R N     1 
ATOM   977  C CA    . LEU A 1 158 ? 118.505 104.906 131.187 1.00 25.57  ? 133 LEU R CA    1 
ATOM   978  C C     . LEU A 1 158 ? 117.734 105.753 132.190 1.00 25.57  ? 133 LEU R C     1 
ATOM   979  O O     . LEU A 1 158 ? 117.403 105.285 133.285 1.00 25.57  ? 133 LEU R O     1 
ATOM   980  C CB    . LEU A 1 158 ? 119.993 105.247 131.231 1.00 25.57  ? 133 LEU R CB    1 
ATOM   981  C CG    . LEU A 1 158 ? 120.689 105.032 132.578 1.00 25.57  ? 133 LEU R CG    1 
ATOM   982  C CD1   . LEU A 1 158 ? 120.504 103.604 133.068 1.00 25.57  ? 133 LEU R CD1   1 
ATOM   983  C CD2   . LEU A 1 158 ? 122.166 105.378 132.478 1.00 25.57  ? 133 LEU R CD2   1 
ATOM   984  N N     . CYS A 1 159 ? 117.444 107.003 131.836 1.00 25.30  ? 134 CYS R N     1 
ATOM   985  C CA    . CYS A 1 159 ? 116.686 107.888 132.711 1.00 25.30  ? 134 CYS R CA    1 
ATOM   986  C C     . CYS A 1 159 ? 115.316 107.296 133.008 1.00 25.30  ? 134 CYS R C     1 
ATOM   987  O O     . CYS A 1 159 ? 114.895 107.236 134.168 1.00 25.30  ? 134 CYS R O     1 
ATOM   988  C CB    . CYS A 1 159 ? 116.539 109.272 132.077 1.00 25.30  ? 134 CYS R CB    1 
ATOM   989  S SG    . CYS A 1 159 ? 118.072 110.224 132.009 1.00 25.30  ? 134 CYS R SG    1 
ATOM   990  N N     . TRP A 1 160 ? 114.612 106.852 131.963 1.00 24.53  ? 135 TRP R N     1 
ATOM   991  C CA    . TRP A 1 160 ? 113.277 106.299 132.176 1.00 24.53  ? 135 TRP R CA    1 
ATOM   992  C C     . TRP A 1 160 ? 113.324 104.992 132.960 1.00 24.53  ? 135 TRP R C     1 
ATOM   993  O O     . TRP A 1 160 ? 112.445 104.736 133.791 1.00 24.53  ? 135 TRP R O     1 
ATOM   994  C CB    . TRP A 1 160 ? 112.567 106.100 130.840 1.00 24.53  ? 135 TRP R CB    1 
ATOM   995  C CG    . TRP A 1 160 ? 111.989 107.367 130.298 1.00 24.53  ? 135 TRP R CG    1 
ATOM   996  C CD1   . TRP A 1 160 ? 112.651 108.345 129.620 1.00 24.53  ? 135 TRP R CD1   1 
ATOM   997  C CD2   . TRP A 1 160 ? 110.629 107.801 130.403 1.00 24.53  ? 135 TRP R CD2   1 
ATOM   998  N NE1   . TRP A 1 160 ? 111.787 109.359 129.289 1.00 24.53  ? 135 TRP R NE1   1 
ATOM   999  C CE2   . TRP A 1 160 ? 110.538 109.048 129.759 1.00 24.53  ? 135 TRP R CE2   1 
ATOM   1000 C CE3   . TRP A 1 160 ? 109.478 107.253 130.976 1.00 24.53  ? 135 TRP R CE3   1 
ATOM   1001 C CZ2   . TRP A 1 160 ? 109.344 109.757 129.671 1.00 24.53  ? 135 TRP R CZ2   1 
ATOM   1002 C CZ3   . TRP A 1 160 ? 108.293 107.958 130.887 1.00 24.53  ? 135 TRP R CZ3   1 
ATOM   1003 C CH2   . TRP A 1 160 ? 108.235 109.196 130.241 1.00 24.53  ? 135 TRP R CH2   1 
ATOM   1004 N N     . LEU A 1 161 ? 114.337 104.158 132.721 1.00 26.20  ? 136 LEU R N     1 
ATOM   1005 C CA    . LEU A 1 161 ? 114.478 102.928 133.491 1.00 26.20  ? 136 LEU R CA    1 
ATOM   1006 C C     . LEU A 1 161 ? 114.708 103.234 134.966 1.00 26.20  ? 136 LEU R C     1 
ATOM   1007 O O     . LEU A 1 161 ? 114.130 102.582 135.843 1.00 26.20  ? 136 LEU R O     1 
ATOM   1008 C CB    . LEU A 1 161 ? 115.626 102.090 132.928 1.00 26.20  ? 136 LEU R CB    1 
ATOM   1009 C CG    . LEU A 1 161 ? 115.908 100.759 133.628 1.00 26.20  ? 136 LEU R CG    1 
ATOM   1010 C CD1   . LEU A 1 161 ? 114.706 99.835  133.546 1.00 26.20  ? 136 LEU R CD1   1 
ATOM   1011 C CD2   . LEU A 1 161 ? 117.135 100.099 133.025 1.00 26.20  ? 136 LEU R CD2   1 
ATOM   1012 N N     . VAL A 1 162 ? 115.554 104.223 135.258 1.00 25.50  ? 137 VAL R N     1 
ATOM   1013 C CA    . VAL A 1 162 ? 115.801 104.597 136.648 1.00 25.50  ? 137 VAL R CA    1 
ATOM   1014 C C     . VAL A 1 162 ? 114.531 105.143 137.283 1.00 25.50  ? 137 VAL R C     1 
ATOM   1015 O O     . VAL A 1 162 ? 114.238 104.870 138.452 1.00 25.50  ? 137 VAL R O     1 
ATOM   1016 C CB    . VAL A 1 162 ? 116.958 105.609 136.735 1.00 25.50  ? 137 VAL R CB    1 
ATOM   1017 C CG1   . VAL A 1 162 ? 117.047 106.193 138.133 1.00 25.50  ? 137 VAL R CG1   1 
ATOM   1018 C CG2   . VAL A 1 162 ? 118.270 104.945 136.355 1.00 25.50  ? 137 VAL R CG2   1 
ATOM   1019 N N     . SER A 1 163 ? 113.764 105.934 136.532 1.00 26.18  ? 138 SER R N     1 
ATOM   1020 C CA    . SER A 1 163 ? 112.499 106.446 137.049 1.00 26.18  ? 138 SER R CA    1 
ATOM   1021 C C     . SER A 1 163 ? 111.562 105.299 137.411 1.00 26.18  ? 138 SER R C     1 
ATOM   1022 O O     . SER A 1 163 ? 110.970 105.275 138.497 1.00 26.18  ? 138 SER R O     1 
ATOM   1023 C CB    . SER A 1 163 ? 111.849 107.369 136.018 1.00 26.18  ? 138 SER R CB    1 
ATOM   1024 O OG    . SER A 1 163 ? 112.741 108.392 135.614 1.00 26.18  ? 138 SER R OG    1 
ATOM   1025 N N     . PHE A 1 164 ? 111.422 104.333 136.499 1.00 27.10  ? 139 PHE R N     1 
ATOM   1026 C CA    . PHE A 1 164 ? 110.568 103.180 136.766 1.00 27.10  ? 139 PHE R CA    1 
ATOM   1027 C C     . PHE A 1 164 ? 111.042 102.418 137.995 1.00 27.10  ? 139 PHE R C     1 
ATOM   1028 O O     . PHE A 1 164 ? 110.235 102.035 138.848 1.00 27.10  ? 139 PHE R O     1 
ATOM   1029 C CB    . PHE A 1 164 ? 110.537 102.251 135.552 1.00 27.10  ? 139 PHE R CB    1 
ATOM   1030 C CG    . PHE A 1 164 ? 109.422 102.542 134.587 1.00 27.10  ? 139 PHE R CG    1 
ATOM   1031 C CD1   . PHE A 1 164 ? 109.516 103.591 133.690 1.00 27.10  ? 139 PHE R CD1   1 
ATOM   1032 C CD2   . PHE A 1 164 ? 108.283 101.758 134.574 1.00 27.10  ? 139 PHE R CD2   1 
ATOM   1033 C CE1   . PHE A 1 164 ? 108.493 103.853 132.802 1.00 27.10  ? 139 PHE R CE1   1 
ATOM   1034 C CE2   . PHE A 1 164 ? 107.257 102.017 133.689 1.00 27.10  ? 139 PHE R CE2   1 
ATOM   1035 C CZ    . PHE A 1 164 ? 107.363 103.066 132.802 1.00 27.10  ? 139 PHE R CZ    1 
ATOM   1036 N N     . LEU A 1 165 ? 112.349 102.190 138.103 1.00 27.69  ? 140 LEU R N     1 
ATOM   1037 C CA    . LEU A 1 165 ? 112.910 101.458 139.232 1.00 27.69  ? 140 LEU R CA    1 
ATOM   1038 C C     . LEU A 1 165 ? 112.600 102.169 140.542 1.00 27.69  ? 140 LEU R C     1 
ATOM   1039 O O     . LEU A 1 165 ? 112.103 101.555 141.494 1.00 27.69  ? 140 LEU R O     1 
ATOM   1040 C CB    . LEU A 1 165 ? 114.422 101.301 139.058 1.00 27.69  ? 140 LEU R CB    1 
ATOM   1041 C CG    . LEU A 1 165 ? 115.127 100.305 139.981 1.00 27.69  ? 140 LEU R CG    1 
ATOM   1042 C CD1   . LEU A 1 165 ? 116.314 99.675  139.270 1.00 27.69  ? 140 LEU R CD1   1 
ATOM   1043 C CD2   . LEU A 1 165 ? 115.571 100.977 141.272 1.00 27.69  ? 140 LEU R CD2   1 
ATOM   1044 N N     . VAL A 1 166 ? 112.882 103.472 140.591 1.00 28.38  ? 141 VAL R N     1 
ATOM   1045 C CA    . VAL A 1 166 ? 112.681 104.238 141.816 1.00 28.38  ? 141 VAL R CA    1 
ATOM   1046 C C     . VAL A 1 166 ? 111.216 104.256 142.209 1.00 28.38  ? 141 VAL R C     1 
ATOM   1047 O O     . VAL A 1 166 ? 110.881 104.120 143.392 1.00 28.38  ? 141 VAL R O     1 
ATOM   1048 C CB    . VAL A 1 166 ? 113.231 105.668 141.642 1.00 28.38  ? 141 VAL R CB    1 
ATOM   1049 C CG1   . VAL A 1 166 ? 112.761 106.563 142.779 1.00 28.38  ? 141 VAL R CG1   1 
ATOM   1050 C CG2   . VAL A 1 166 ? 114.746 105.644 141.566 1.00 28.38  ? 141 VAL R CG2   1 
ATOM   1051 N N     . GLY A 1 167 ? 110.319 104.424 141.241 1.00 29.34  ? 142 GLY R N     1 
ATOM   1052 C CA    . GLY A 1 167 ? 108.913 104.531 141.566 1.00 29.34  ? 142 GLY R CA    1 
ATOM   1053 C C     . GLY A 1 167 ? 108.239 103.208 141.871 1.00 29.34  ? 142 GLY R C     1 
ATOM   1054 O O     . GLY A 1 167 ? 107.236 103.183 142.588 1.00 29.34  ? 142 GLY R O     1 
ATOM   1055 N N     . LEU A 1 168 ? 108.768 102.102 141.343 1.00 30.75  ? 143 LEU R N     1 
ATOM   1056 C CA    . LEU A 1 168 ? 108.209 100.783 141.607 1.00 30.75  ? 143 LEU R CA    1 
ATOM   1057 C C     . LEU A 1 168 ? 108.923 100.042 142.728 1.00 30.75  ? 143 LEU R C     1 
ATOM   1058 O O     . LEU A 1 168 ? 108.503 98.935  143.078 1.00 30.75  ? 143 LEU R O     1 
ATOM   1059 C CB    . LEU A 1 168 ? 108.247 99.928  140.334 1.00 30.75  ? 143 LEU R CB    1 
ATOM   1060 C CG    . LEU A 1 168 ? 107.250 100.312 139.238 1.00 30.75  ? 143 LEU R CG    1 
ATOM   1061 C CD1   . LEU A 1 168 ? 107.575 99.581  137.948 1.00 30.75  ? 143 LEU R CD1   1 
ATOM   1062 C CD2   . LEU A 1 168 ? 105.825 100.012 139.672 1.00 30.75  ? 143 LEU R CD2   1 
ATOM   1063 N N     . THR A 1 169 ? 109.982 100.617 143.296 1.00 34.55  ? 144 THR R N     1 
ATOM   1064 C CA    . THR A 1 169 ? 110.633 100.007 144.454 1.00 34.55  ? 144 THR R CA    1 
ATOM   1065 C C     . THR A 1 169 ? 109.668 99.665  145.583 1.00 34.55  ? 144 THR R C     1 
ATOM   1066 O O     . THR A 1 169 ? 109.822 98.591  146.186 1.00 34.55  ? 144 THR R O     1 
ATOM   1067 C CB    . THR A 1 169 ? 111.739 100.943 144.958 1.00 34.55  ? 144 THR R CB    1 
ATOM   1068 O OG1   . THR A 1 169 ? 112.751 101.077 143.952 1.00 34.55  ? 144 THR R OG1   1 
ATOM   1069 C CG2   . THR A 1 169 ? 112.365 100.396 146.232 1.00 34.55  ? 144 THR R CG2   1 
ATOM   1070 N N     . PRO A 1 170 ? 108.682 100.500 145.926 1.00 37.72  ? 145 PRO R N     1 
ATOM   1071 C CA    . PRO A 1 170 ? 107.828 100.175 147.082 1.00 37.72  ? 145 PRO R CA    1 
ATOM   1072 C C     . PRO A 1 170 ? 107.137 98.826  146.980 1.00 37.72  ? 145 PRO R C     1 
ATOM   1073 O O     . PRO A 1 170 ? 106.896 98.190  148.013 1.00 37.72  ? 145 PRO R O     1 
ATOM   1074 C CB    . PRO A 1 170 ? 106.814 101.327 147.100 1.00 37.72  ? 145 PRO R CB    1 
ATOM   1075 C CG    . PRO A 1 170 ? 107.498 102.445 146.412 1.00 37.72  ? 145 PRO R CG    1 
ATOM   1076 C CD    . PRO A 1 170 ? 108.344 101.814 145.353 1.00 37.72  ? 145 PRO R CD    1 
ATOM   1077 N N     . MET A 1 171 ? 106.808 98.365  145.772 1.00 38.95  ? 146 MET R N     1 
ATOM   1078 C CA    . MET A 1 171 ? 106.139 97.077  145.628 1.00 38.95  ? 146 MET R CA    1 
ATOM   1079 C C     . MET A 1 171 ? 107.008 95.906  146.064 1.00 38.95  ? 146 MET R C     1 
ATOM   1080 O O     . MET A 1 171 ? 106.480 94.802  146.239 1.00 38.95  ? 146 MET R O     1 
ATOM   1081 C CB    . MET A 1 171 ? 105.707 96.865  144.178 1.00 38.95  ? 146 MET R CB    1 
ATOM   1082 C CG    . MET A 1 171 ? 104.598 97.785  143.718 1.00 38.95  ? 146 MET R CG    1 
ATOM   1083 S SD    . MET A 1 171 ? 104.097 97.451  142.019 1.00 38.95  ? 146 MET R SD    1 
ATOM   1084 C CE    . MET A 1 171 ? 102.967 98.805  141.728 1.00 38.95  ? 146 MET R CE    1 
ATOM   1085 N N     . PHE A 1 172 ? 108.313 96.110  146.243 1.00 41.64  ? 147 PHE R N     1 
ATOM   1086 C CA    . PHE A 1 172 ? 109.230 95.039  146.605 1.00 41.64  ? 147 PHE R CA    1 
ATOM   1087 C C     . PHE A 1 172 ? 109.545 95.016  148.098 1.00 41.64  ? 147 PHE R C     1 
ATOM   1088 O O     . PHE A 1 172 ? 110.648 94.613  148.485 1.00 41.64  ? 147 PHE R O     1 
ATOM   1089 C CB    . PHE A 1 172 ? 110.524 95.156  145.796 1.00 41.64  ? 147 PHE R CB    1 
ATOM   1090 C CG    . PHE A 1 172 ? 110.339 94.934  144.320 1.00 41.64  ? 147 PHE R CG    1 
ATOM   1091 C CD1   . PHE A 1 172 ? 109.701 95.879  143.536 1.00 41.64  ? 147 PHE R CD1   1 
ATOM   1092 C CD2   . PHE A 1 172 ? 110.797 93.773  143.720 1.00 41.64  ? 147 PHE R CD2   1 
ATOM   1093 C CE1   . PHE A 1 172 ? 109.531 95.675  142.180 1.00 41.64  ? 147 PHE R CE1   1 
ATOM   1094 C CE2   . PHE A 1 172 ? 110.628 93.563  142.365 1.00 41.64  ? 147 PHE R CE2   1 
ATOM   1095 C CZ    . PHE A 1 172 ? 109.994 94.515  141.595 1.00 41.64  ? 147 PHE R CZ    1 
ATOM   1096 N N     . GLY A 1 173 ? 108.607 95.442  148.941 1.00 46.64  ? 148 GLY R N     1 
ATOM   1097 C CA    . GLY A 1 173 ? 108.760 95.294  150.376 1.00 46.64  ? 148 GLY R CA    1 
ATOM   1098 C C     . GLY A 1 173 ? 108.539 96.561  151.179 1.00 46.64  ? 148 GLY R C     1 
ATOM   1099 O O     . GLY A 1 173 ? 107.964 96.509  152.270 1.00 46.64  ? 148 GLY R O     1 
ATOM   1100 N N     . TRP A 1 174 ? 108.983 97.705  150.658 1.00 49.07  ? 149 TRP R N     1 
ATOM   1101 C CA    . TRP A 1 174 ? 108.885 98.971  151.386 1.00 49.07  ? 149 TRP R CA    1 
ATOM   1102 C C     . TRP A 1 174 ? 107.499 99.567  151.160 1.00 49.07  ? 149 TRP R C     1 
ATOM   1103 O O     . TRP A 1 174 ? 107.229 100.263 150.178 1.00 49.07  ? 149 TRP R O     1 
ATOM   1104 C CB    . TRP A 1 174 ? 109.987 99.932  150.956 1.00 49.07  ? 149 TRP R CB    1 
ATOM   1105 C CG    . TRP A 1 174 ? 111.365 99.496  151.368 1.00 49.07  ? 149 TRP R CG    1 
ATOM   1106 C CD1   . TRP A 1 174 ? 111.684 98.463  152.203 1.00 49.07  ? 149 TRP R CD1   1 
ATOM   1107 C CD2   . TRP A 1 174 ? 112.608 100.089 150.973 1.00 49.07  ? 149 TRP R CD2   1 
ATOM   1108 N NE1   . TRP A 1 174 ? 113.047 98.374  152.346 1.00 49.07  ? 149 TRP R NE1   1 
ATOM   1109 C CE2   . TRP A 1 174 ? 113.638 99.361  151.602 1.00 49.07  ? 149 TRP R CE2   1 
ATOM   1110 C CE3   . TRP A 1 174 ? 112.951 101.164 150.147 1.00 49.07  ? 149 TRP R CE3   1 
ATOM   1111 C CZ2   . TRP A 1 174 ? 114.985 99.672  151.431 1.00 49.07  ? 149 TRP R CZ2   1 
ATOM   1112 C CZ3   . TRP A 1 174 ? 114.290 101.471 149.978 1.00 49.07  ? 149 TRP R CZ3   1 
ATOM   1113 C CH2   . TRP A 1 174 ? 115.290 100.728 150.617 1.00 49.07  ? 149 TRP R CH2   1 
ATOM   1114 N N     . ASN A 1 175 ? 106.601 99.276  152.098 1.00 50.38  ? 150 ASN R N     1 
ATOM   1115 C CA    . ASN A 1 175 ? 105.267 99.857  152.103 1.00 50.38  ? 150 ASN R CA    1 
ATOM   1116 C C     . ASN A 1 175 ? 104.687 99.731  153.504 1.00 50.38  ? 150 ASN R C     1 
ATOM   1117 O O     . ASN A 1 175 ? 105.275 99.103  154.389 1.00 50.38  ? 150 ASN R O     1 
ATOM   1118 C CB    . ASN A 1 175 ? 104.361 99.194  151.056 1.00 50.38  ? 150 ASN R CB    1 
ATOM   1119 C CG    . ASN A 1 175 ? 104.116 97.724  151.337 1.00 50.38  ? 150 ASN R CG    1 
ATOM   1120 O OD1   . ASN A 1 175 ? 104.513 97.199  152.376 1.00 50.38  ? 150 ASN R OD1   1 
ATOM   1121 N ND2   . ASN A 1 175 ? 103.457 97.050  150.402 1.00 50.38  ? 150 ASN R ND2   1 
ATOM   1122 N N     . MET A 1 176 ? 103.518 100.344 153.701 1.00 51.30  ? 151 MET R N     1 
ATOM   1123 C CA    . MET A 1 176 ? 102.897 100.340 155.022 1.00 51.30  ? 151 MET R CA    1 
ATOM   1124 C C     . MET A 1 176 ? 102.568 98.923  155.476 1.00 51.30  ? 151 MET R C     1 
ATOM   1125 O O     . MET A 1 176 ? 102.601 98.626  156.677 1.00 51.30  ? 151 MET R O     1 
ATOM   1126 C CB    . MET A 1 176 ? 101.635 101.204 155.009 1.00 51.30  ? 151 MET R CB    1 
ATOM   1127 C CG    . MET A 1 176 ? 101.906 102.698 154.916 1.00 51.30  ? 151 MET R CG    1 
ATOM   1128 S SD    . MET A 1 176 ? 102.788 103.350 156.347 1.00 51.30  ? 151 MET R SD    1 
ATOM   1129 C CE    . MET A 1 176 ? 101.524 103.232 157.610 1.00 51.30  ? 151 MET R CE    1 
ATOM   1130 N N     . LYS A 1 177 ? 102.249 98.033  154.533 1.00 58.99  ? 152 LYS R N     1 
ATOM   1131 C CA    . LYS A 1 177 ? 101.888 96.668  154.899 1.00 58.99  ? 152 LYS R CA    1 
ATOM   1132 C C     . LYS A 1 177 ? 102.992 95.987  155.695 1.00 58.99  ? 152 LYS R C     1 
ATOM   1133 O O     . LYS A 1 177 ? 102.710 95.150  156.560 1.00 58.99  ? 152 LYS R O     1 
ATOM   1134 C CB    . LYS A 1 177 ? 101.569 95.857  153.641 1.00 58.99  ? 152 LYS R CB    1 
ATOM   1135 C CG    . LYS A 1 177 ? 101.077 94.441  153.912 1.00 58.99  ? 152 LYS R CG    1 
ATOM   1136 C CD    . LYS A 1 177 ? 99.700  94.448  154.555 1.00 58.99  ? 152 LYS R CD    1 
ATOM   1137 C CE    . LYS A 1 177 ? 99.136  93.043  154.681 1.00 58.99  ? 152 LYS R CE    1 
ATOM   1138 N NZ    . LYS A 1 177 ? 97.803  93.036  155.345 1.00 58.99  ? 152 LYS R NZ    1 
ATOM   1139 N N     . LEU A 1 178 ? 104.253 96.329  155.421 1.00 56.93  ? 153 LEU R N     1 
ATOM   1140 C CA    . LEU A 1 178 ? 105.364 95.712  156.135 1.00 56.93  ? 153 LEU R CA    1 
ATOM   1141 C C     . LEU A 1 178 ? 105.346 96.028  157.625 1.00 56.93  ? 153 LEU R C     1 
ATOM   1142 O O     . LEU A 1 178 ? 105.959 95.293  158.406 1.00 56.93  ? 153 LEU R O     1 
ATOM   1143 C CB    . LEU A 1 178 ? 106.693 96.168  155.529 1.00 56.93  ? 153 LEU R CB    1 
ATOM   1144 C CG    . LEU A 1 178 ? 107.938 95.390  155.966 1.00 56.93  ? 153 LEU R CG    1 
ATOM   1145 C CD1   . LEU A 1 178 ? 107.892 93.957  155.458 1.00 56.93  ? 153 LEU R CD1   1 
ATOM   1146 C CD2   . LEU A 1 178 ? 109.201 96.090  155.488 1.00 56.93  ? 153 LEU R CD2   1 
ATOM   1147 N N     . SER A 1 179 ? 104.660 97.096  158.035 1.00 58.91  ? 154 SER R N     1 
ATOM   1148 C CA    . SER A 1 179 ? 104.613 97.499  159.433 1.00 58.91  ? 154 SER R CA    1 
ATOM   1149 C C     . SER A 1 179 ? 103.253 97.287  160.081 1.00 58.91  ? 154 SER R C     1 
ATOM   1150 O O     . SER A 1 179 ? 103.166 97.305  161.314 1.00 58.91  ? 154 SER R O     1 
ATOM   1151 C CB    . SER A 1 179 ? 105.005 98.979  159.568 1.00 58.91  ? 154 SER R CB    1 
ATOM   1152 O OG    . SER A 1 179 ? 106.380 99.169  159.287 1.00 58.91  ? 154 SER R OG    1 
ATOM   1153 N N     . SER A 1 180 ? 102.197 97.087  159.297 1.00 65.55  ? 155 SER R N     1 
ATOM   1154 C CA    . SER A 1 180 ? 100.863 96.906  159.852 1.00 65.55  ? 155 SER R CA    1 
ATOM   1155 C C     . SER A 1 180 ? 100.783 95.587  160.609 1.00 65.55  ? 155 SER R C     1 
ATOM   1156 O O     . SER A 1 180 ? 101.254 94.553  160.126 1.00 65.55  ? 155 SER R O     1 
ATOM   1157 C CB    . SER A 1 180 ? 99.816  96.940  158.739 1.00 65.55  ? 155 SER R CB    1 
ATOM   1158 O OG    . SER A 1 180 ? 99.835  98.183  158.059 1.00 65.55  ? 155 SER R OG    1 
ATOM   1159 N N     . ALA A 1 181 ? 100.184 95.628  161.801 1.00 71.08  ? 156 ALA R N     1 
ATOM   1160 C CA    . ALA A 1 181 ? 100.001 94.419  162.594 1.00 71.08  ? 156 ALA R CA    1 
ATOM   1161 C C     . ALA A 1 181 ? 98.793  93.606  162.150 1.00 71.08  ? 156 ALA R C     1 
ATOM   1162 O O     . ALA A 1 181 ? 98.669  92.441  162.544 1.00 71.08  ? 156 ALA R O     1 
ATOM   1163 C CB    . ALA A 1 181 ? 99.859  94.778  164.074 1.00 71.08  ? 156 ALA R CB    1 
ATOM   1164 N N     . ASP A 1 182 ? 97.904  94.188  161.343 1.00 72.53  ? 157 ASP R N     1 
ATOM   1165 C CA    . ASP A 1 182 ? 96.716  93.488  160.853 1.00 72.53  ? 157 ASP R CA    1 
ATOM   1166 C C     . ASP A 1 182 ? 97.015  92.952  159.456 1.00 72.53  ? 157 ASP R C     1 
ATOM   1167 O O     . ASP A 1 182 ? 96.698  93.562  158.433 1.00 72.53  ? 157 ASP R O     1 
ATOM   1168 C CB    . ASP A 1 182 ? 95.508  94.416  160.858 1.00 72.53  ? 157 ASP R CB    1 
ATOM   1169 C CG    . ASP A 1 182 ? 94.771  94.408  162.183 1.00 72.53  ? 157 ASP R CG    1 
ATOM   1170 O OD1   . ASP A 1 182 ? 94.463  93.308  162.688 1.00 72.53  ? 157 ASP R OD1   1 
ATOM   1171 O OD2   . ASP A 1 182 ? 94.501  95.502  162.721 1.00 72.53  ? 157 ASP R OD2   1 
ATOM   1172 N N     . GLU A 1 183 ? 97.642  91.775  159.423 1.00 72.12  ? 158 GLU R N     1 
ATOM   1173 C CA    . GLU A 1 183 ? 98.006  91.148  158.159 1.00 72.12  ? 158 GLU R CA    1 
ATOM   1174 C C     . GLU A 1 183 ? 96.798  90.663  157.370 1.00 72.12  ? 158 GLU R C     1 
ATOM   1175 O O     . GLU A 1 183 ? 96.951  90.312  156.195 1.00 72.12  ? 158 GLU R O     1 
ATOM   1176 C CB    . GLU A 1 183 ? 98.956  89.975  158.412 1.00 72.12  ? 158 GLU R CB    1 
ATOM   1177 C CG    . GLU A 1 183 ? 100.356 90.388  158.848 1.00 72.12  ? 158 GLU R CG    1 
ATOM   1178 C CD    . GLU A 1 183 ? 100.418 90.818  160.302 1.00 72.12  ? 158 GLU R CD    1 
ATOM   1179 O OE1   . GLU A 1 183 ? 99.545  90.394  161.089 1.00 72.12  ? 158 GLU R OE1   1 
ATOM   1180 O OE2   . GLU A 1 183 ? 101.342 91.579  160.659 1.00 72.12  ? 158 GLU R OE2   1 
ATOM   1181 N N     . ASN A 1 184 ? 95.614  90.633  157.976 1.00 70.80  ? 159 ASN R N     1 
ATOM   1182 C CA    . ASN A 1 184 ? 94.408  90.150  157.316 1.00 70.80  ? 159 ASN R CA    1 
ATOM   1183 C C     . ASN A 1 184 ? 93.606  91.260  156.649 1.00 70.80  ? 159 ASN R C     1 
ATOM   1184 O O     . ASN A 1 184 ? 92.525  90.987  156.117 1.00 70.80  ? 159 ASN R O     1 
ATOM   1185 C CB    . ASN A 1 184 ? 93.520  89.415  158.325 1.00 70.80  ? 159 ASN R CB    1 
ATOM   1186 C CG    . ASN A 1 184 ? 94.269  88.339  159.086 1.00 70.80  ? 159 ASN R CG    1 
ATOM   1187 O OD1   . ASN A 1 184 ? 95.147  87.673  158.538 1.00 70.80  ? 159 ASN R OD1   1 
ATOM   1188 N ND2   . ASN A 1 184 ? 93.924  88.163  160.356 1.00 70.80  ? 159 ASN R ND2   1 
ATOM   1189 N N     . LEU A 1 185 ? 94.099  92.497  156.661 1.00 67.04  ? 160 LEU R N     1 
ATOM   1190 C CA    . LEU A 1 185 ? 93.377  93.621  156.074 1.00 67.04  ? 160 LEU R CA    1 
ATOM   1191 C C     . LEU A 1 185 ? 93.584  93.610  154.564 1.00 67.04  ? 160 LEU R C     1 
ATOM   1192 O O     . LEU A 1 185 ? 94.707  93.787  154.081 1.00 67.04  ? 160 LEU R O     1 
ATOM   1193 C CB    . LEU A 1 185 ? 93.855  94.936  156.684 1.00 67.04  ? 160 LEU R CB    1 
ATOM   1194 C CG    . LEU A 1 185 ? 92.985  96.159  156.390 1.00 67.04  ? 160 LEU R CG    1 
ATOM   1195 C CD1   . LEU A 1 185 ? 91.703  96.117  157.208 1.00 67.04  ? 160 LEU R CD1   1 
ATOM   1196 C CD2   . LEU A 1 185 ? 93.757  97.441  156.664 1.00 67.04  ? 160 LEU R CD2   1 
ATOM   1197 N N     . THR A 1 186 ? 92.499  93.404  153.817 1.00 64.56  ? 161 THR R N     1 
ATOM   1198 C CA    . THR A 1 186 ? 92.545  93.339  152.361 1.00 64.56  ? 161 THR R CA    1 
ATOM   1199 C C     . THR A 1 186 ? 91.960  94.575  151.690 1.00 64.56  ? 161 THR R C     1 
ATOM   1200 O O     . THR A 1 186 ? 92.572  95.116  150.765 1.00 64.56  ? 161 THR R O     1 
ATOM   1201 C CB    . THR A 1 186 ? 91.794  92.099  151.865 1.00 64.56  ? 161 THR R CB    1 
ATOM   1202 O OG1   . THR A 1 186 ? 90.508  92.030  152.493 1.00 64.56  ? 161 THR R OG1   1 
ATOM   1203 C CG2   . THR A 1 186 ? 92.581  90.835  152.183 1.00 64.56  ? 161 THR R CG2   1 
ATOM   1204 N N     . PHE A 1 187 ? 90.794  95.035  152.134 1.00 61.02  ? 162 PHE R N     1 
ATOM   1205 C CA    . PHE A 1 187 ? 90.127  96.193  151.557 1.00 61.02  ? 162 PHE R CA    1 
ATOM   1206 C C     . PHE A 1 187 ? 90.231  97.368  152.517 1.00 61.02  ? 162 PHE R C     1 
ATOM   1207 O O     . PHE A 1 187 ? 90.003  97.213  153.721 1.00 61.02  ? 162 PHE R O     1 
ATOM   1208 C CB    . PHE A 1 187 ? 88.658  95.889  151.256 1.00 61.02  ? 162 PHE R CB    1 
ATOM   1209 C CG    . PHE A 1 187 ? 88.448  95.092  150.001 1.00 61.02  ? 162 PHE R CG    1 
ATOM   1210 C CD1   . PHE A 1 187 ? 88.676  93.726  149.984 1.00 61.02  ? 162 PHE R CD1   1 
ATOM   1211 C CD2   . PHE A 1 187 ? 88.022  95.710  148.838 1.00 61.02  ? 162 PHE R CD2   1 
ATOM   1212 C CE1   . PHE A 1 187 ? 88.483  92.993  148.829 1.00 61.02  ? 162 PHE R CE1   1 
ATOM   1213 C CE2   . PHE A 1 187 ? 87.827  94.982  147.680 1.00 61.02  ? 162 PHE R CE2   1 
ATOM   1214 C CZ    . PHE A 1 187 ? 88.057  93.622  147.676 1.00 61.02  ? 162 PHE R CZ    1 
ATOM   1215 N N     . LEU A 1 188 ? 90.578  98.534  151.986 1.00 56.86  ? 163 LEU R N     1 
ATOM   1216 C CA    . LEU A 1 188 ? 90.704  99.736  152.795 1.00 56.86  ? 163 LEU R CA    1 
ATOM   1217 C C     . LEU A 1 188 ? 90.487  100.945 151.907 1.00 56.86  ? 163 LEU R C     1 
ATOM   1218 O O     . LEU A 1 188 ? 90.592  100.854 150.672 1.00 56.86  ? 163 LEU R O     1 
ATOM   1219 C CB    . LEU A 1 188 ? 92.072  99.808  153.485 1.00 56.86  ? 163 LEU R CB    1 
ATOM   1220 C CG    . LEU A 1 188 ? 93.309  99.771  152.583 1.00 56.86  ? 163 LEU R CG    1 
ATOM   1221 C CD1   . LEU A 1 188 ? 93.700  101.165 152.111 1.00 56.86  ? 163 LEU R CD1   1 
ATOM   1222 C CD2   . LEU A 1 188 ? 94.471  99.110  153.308 1.00 56.86  ? 163 LEU R CD2   1 
ATOM   1223 N N     . PRO A 1 189 ? 90.159  102.097 152.495 1.00 54.67  ? 164 PRO R N     1 
ATOM   1224 C CA    . PRO A 1 189 ? 90.109  103.340 151.716 1.00 54.67  ? 164 PRO R CA    1 
ATOM   1225 C C     . PRO A 1 189 ? 91.510  103.777 151.316 1.00 54.67  ? 164 PRO R C     1 
ATOM   1226 O O     . PRO A 1 189 ? 92.424  103.821 152.143 1.00 54.67  ? 164 PRO R O     1 
ATOM   1227 C CB    . PRO A 1 189 ? 89.451  104.337 152.675 1.00 54.67  ? 164 PRO R CB    1 
ATOM   1228 C CG    . PRO A 1 189 ? 89.767  103.810 154.031 1.00 54.67  ? 164 PRO R CG    1 
ATOM   1229 C CD    . PRO A 1 189 ? 89.760  102.314 153.898 1.00 54.67  ? 164 PRO R CD    1 
ATOM   1230 N N     . CYS A 1 190 ? 91.670  104.103 150.039 1.00 51.64  ? 165 CYS R N     1 
ATOM   1231 C CA    . CYS A 1 190 ? 92.984  104.379 149.467 1.00 51.64  ? 165 CYS R CA    1 
ATOM   1232 C C     . CYS A 1 190 ? 93.416  105.797 149.816 1.00 51.64  ? 165 CYS R C     1 
ATOM   1233 O O     . CYS A 1 190 ? 92.947  106.769 149.221 1.00 51.64  ? 165 CYS R O     1 
ATOM   1234 C CB    . CYS A 1 190 ? 92.945  104.173 147.959 1.00 51.64  ? 165 CYS R CB    1 
ATOM   1235 S SG    . CYS A 1 190 ? 94.368  104.828 147.086 1.00 51.64  ? 165 CYS R SG    1 
ATOM   1236 N N     . ARG A 1 191 ? 94.327  105.916 150.777 1.00 46.57  ? 166 ARG R N     1 
ATOM   1237 C CA    . ARG A 1 191 ? 94.950  107.181 151.130 1.00 46.57  ? 166 ARG R CA    1 
ATOM   1238 C C     . ARG A 1 191 ? 96.453  107.058 150.931 1.00 46.57  ? 166 ARG R C     1 
ATOM   1239 O O     . ARG A 1 191 ? 97.055  106.046 151.305 1.00 46.57  ? 166 ARG R O     1 
ATOM   1240 C CB    . ARG A 1 191 ? 94.638  107.575 152.577 1.00 46.57  ? 166 ARG R CB    1 
ATOM   1241 C CG    . ARG A 1 191 ? 93.164  107.841 152.837 1.00 46.57  ? 166 ARG R CG    1 
ATOM   1242 C CD    . ARG A 1 191 ? 92.924  108.387 154.237 1.00 46.57  ? 166 ARG R CD    1 
ATOM   1243 N NE    . ARG A 1 191 ? 93.624  109.645 154.467 1.00 46.57  ? 166 ARG R NE    1 
ATOM   1244 C CZ    . ARG A 1 191 ? 93.491  110.389 155.556 1.00 46.57  ? 166 ARG R CZ    1 
ATOM   1245 N NH1   . ARG A 1 191 ? 92.683  110.034 156.543 1.00 46.57  ? 166 ARG R NH1   1 
ATOM   1246 N NH2   . ARG A 1 191 ? 94.184  111.520 155.659 1.00 46.57  ? 166 ARG R NH2   1 
ATOM   1247 N N     . PHE A 1 192 ? 97.055  108.091 150.338 1.00 37.26  ? 167 PHE R N     1 
ATOM   1248 C CA    . PHE A 1 192 ? 98.475  108.027 150.012 1.00 37.26  ? 167 PHE R CA    1 
ATOM   1249 C C     . PHE A 1 192 ? 99.307  107.689 151.242 1.00 37.26  ? 167 PHE R C     1 
ATOM   1250 O O     . PHE A 1 192 ? 100.317 106.983 151.146 1.00 37.26  ? 167 PHE R O     1 
ATOM   1251 C CB    . PHE A 1 192 ? 98.937  109.352 149.406 1.00 37.26  ? 167 PHE R CB    1 
ATOM   1252 C CG    . PHE A 1 192 ? 100.344 109.318 148.881 1.00 37.26  ? 167 PHE R CG    1 
ATOM   1253 C CD1   . PHE A 1 192 ? 101.420 109.540 149.723 1.00 37.26  ? 167 PHE R CD1   1 
ATOM   1254 C CD2   . PHE A 1 192 ? 100.589 109.055 147.545 1.00 37.26  ? 167 PHE R CD2   1 
ATOM   1255 C CE1   . PHE A 1 192 ? 102.712 109.504 149.240 1.00 37.26  ? 167 PHE R CE1   1 
ATOM   1256 C CE2   . PHE A 1 192 ? 101.877 109.019 147.057 1.00 37.26  ? 167 PHE R CE2   1 
ATOM   1257 C CZ    . PHE A 1 192 ? 102.940 109.242 147.905 1.00 37.26  ? 167 PHE R CZ    1 
ATOM   1258 N N     . ARG A 1 193 ? 98.899  108.186 152.409 1.00 42.54  ? 168 ARG R N     1 
ATOM   1259 C CA    . ARG A 1 193 ? 99.621  107.911 153.643 1.00 42.54  ? 168 ARG R CA    1 
ATOM   1260 C C     . ARG A 1 193 ? 99.321  106.531 154.211 1.00 42.54  ? 168 ARG R C     1 
ATOM   1261 O O     . ARG A 1 193 ? 100.008 106.102 155.144 1.00 42.54  ? 168 ARG R O     1 
ATOM   1262 C CB    . ARG A 1 193 ? 99.287  108.976 154.690 1.00 42.54  ? 168 ARG R CB    1 
ATOM   1263 C CG    . ARG A 1 193 ? 99.562  110.402 154.226 1.00 42.54  ? 168 ARG R CG    1 
ATOM   1264 C CD    . ARG A 1 193 ? 99.952  111.331 155.372 1.00 42.54  ? 168 ARG R CD    1 
ATOM   1265 N NE    . ARG A 1 193 ? 100.985 110.764 156.233 1.00 42.54  ? 168 ARG R NE    1 
ATOM   1266 C CZ    . ARG A 1 193 ? 101.126 111.038 157.523 1.00 42.54  ? 168 ARG R CZ    1 
ATOM   1267 N NH1   . ARG A 1 193 ? 100.320 111.883 158.146 1.00 42.54  ? 168 ARG R NH1   1 
ATOM   1268 N NH2   . ARG A 1 193 ? 102.104 110.450 158.206 1.00 42.54  ? 168 ARG R NH2   1 
ATOM   1269 N N     . SER A 1 194 ? 98.320  105.830 153.679 1.00 45.43  ? 169 SER R N     1 
ATOM   1270 C CA    . SER A 1 194 ? 97.969  104.501 154.160 1.00 45.43  ? 169 SER R CA    1 
ATOM   1271 C C     . SER A 1 194 ? 98.735  103.387 153.457 1.00 45.43  ? 169 SER R C     1 
ATOM   1272 O O     . SER A 1 194 ? 98.663  102.237 153.902 1.00 45.43  ? 169 SER R O     1 
ATOM   1273 C CB    . SER A 1 194 ? 96.466  104.261 153.989 1.00 45.43  ? 169 SER R CB    1 
ATOM   1274 O OG    . SER A 1 194 ? 95.717  105.058 154.890 1.00 45.43  ? 169 SER R OG    1 
ATOM   1275 N N     . VAL A 1 195 ? 99.462  103.694 152.381 1.00 44.49  ? 170 VAL R N     1 
ATOM   1276 C CA    . VAL A 1 195 ? 100.199 102.698 151.618 1.00 44.49  ? 170 VAL R CA    1 
ATOM   1277 C C     . VAL A 1 195 ? 101.681 103.035 151.522 1.00 44.49  ? 170 VAL R C     1 
ATOM   1278 O O     . VAL A 1 195 ? 102.533 102.159 151.706 1.00 44.49  ? 170 VAL R O     1 
ATOM   1279 C CB    . VAL A 1 195 ? 99.594  102.520 150.208 1.00 44.49  ? 170 VAL R CB    1 
ATOM   1280 C CG1   . VAL A 1 195 ? 98.135  102.115 150.309 1.00 44.49  ? 170 VAL R CG1   1 
ATOM   1281 C CG2   . VAL A 1 195 ? 99.739  103.793 149.389 1.00 44.49  ? 170 VAL R CG2   1 
ATOM   1282 N N     . MET A 1 196 ? 102.014 104.292 151.238 1.00 39.71  ? 171 MET R N     1 
ATOM   1283 C CA    . MET A 1 196 ? 103.397 104.707 151.028 1.00 39.71  ? 171 MET R CA    1 
ATOM   1284 C C     . MET A 1 196 ? 103.991 105.168 152.353 1.00 39.71  ? 171 MET R C     1 
ATOM   1285 O O     . MET A 1 196 ? 103.538 106.158 152.935 1.00 39.71  ? 171 MET R O     1 
ATOM   1286 C CB    . MET A 1 196 ? 103.466 105.820 149.986 1.00 39.71  ? 171 MET R CB    1 
ATOM   1287 C CG    . MET A 1 196 ? 104.876 106.116 149.486 1.00 39.71  ? 171 MET R CG    1 
ATOM   1288 S SD    . MET A 1 196 ? 105.445 105.058 148.139 1.00 39.71  ? 171 MET R SD    1 
ATOM   1289 C CE    . MET A 1 196 ? 104.077 105.151 146.989 1.00 39.71  ? 171 MET R CE    1 
ATOM   1290 N N     . ARG A 1 197 ? 105.007 104.453 152.829 1.00 44.47  ? 172 ARG R N     1 
ATOM   1291 C CA    . ARG A 1 197 ? 105.714 104.882 154.025 1.00 44.47  ? 172 ARG R CA    1 
ATOM   1292 C C     . ARG A 1 197 ? 106.356 106.242 153.787 1.00 44.47  ? 172 ARG R C     1 
ATOM   1293 O O     . ARG A 1 197 ? 107.027 106.462 152.776 1.00 44.47  ? 172 ARG R O     1 
ATOM   1294 C CB    . ARG A 1 197 ? 106.781 103.856 154.406 1.00 44.47  ? 172 ARG R CB    1 
ATOM   1295 C CG    . ARG A 1 197 ? 106.230 102.481 154.744 1.00 44.47  ? 172 ARG R CG    1 
ATOM   1296 C CD    . ARG A 1 197 ? 107.298 101.583 155.351 1.00 44.47  ? 172 ARG R CD    1 
ATOM   1297 N NE    . ARG A 1 197 ? 107.803 102.098 156.618 1.00 44.47  ? 172 ARG R NE    1 
ATOM   1298 C CZ    . ARG A 1 197 ? 108.769 101.529 157.328 1.00 44.47  ? 172 ARG R CZ    1 
ATOM   1299 N NH1   . ARG A 1 197 ? 109.359 100.416 156.924 1.00 44.47  ? 172 ARG R NH1   1 
ATOM   1300 N NH2   . ARG A 1 197 ? 109.152 102.091 158.471 1.00 44.47  ? 172 ARG R NH2   1 
ATOM   1301 N N     . MET A 1 198 ? 106.150 107.162 154.732 1.00 40.28  ? 173 MET R N     1 
ATOM   1302 C CA    . MET A 1 198 ? 106.698 108.505 154.575 1.00 40.28  ? 173 MET R CA    1 
ATOM   1303 C C     . MET A 1 198 ? 108.220 108.492 154.581 1.00 40.28  ? 173 MET R C     1 
ATOM   1304 O O     . MET A 1 198 ? 108.850 109.347 153.947 1.00 40.28  ? 173 MET R O     1 
ATOM   1305 C CB    . MET A 1 198 ? 106.169 109.418 155.680 1.00 40.28  ? 173 MET R CB    1 
ATOM   1306 C CG    . MET A 1 198 ? 104.682 109.727 155.573 1.00 40.28  ? 173 MET R CG    1 
ATOM   1307 S SD    . MET A 1 198 ? 104.320 111.108 154.471 1.00 40.28  ? 173 MET R SD    1 
ATOM   1308 C CE    . MET A 1 198 ? 104.183 110.271 152.892 1.00 40.28  ? 173 MET R CE    1 
ATOM   1309 N N     . ASP A 1 199 ? 108.828 107.533 155.284 1.00 40.62  ? 174 ASP R N     1 
ATOM   1310 C CA    . ASP A 1 199 ? 110.283 107.436 155.288 1.00 40.62  ? 174 ASP R CA    1 
ATOM   1311 C C     . ASP A 1 199 ? 110.826 107.181 153.890 1.00 40.62  ? 174 ASP R C     1 
ATOM   1312 O O     . ASP A 1 199 ? 111.881 107.716 153.530 1.00 40.62  ? 174 ASP R O     1 
ATOM   1313 C CB    . ASP A 1 199 ? 110.733 106.332 156.245 1.00 40.62  ? 174 ASP R CB    1 
ATOM   1314 C CG    . ASP A 1 199 ? 110.253 104.958 155.821 1.00 40.62  ? 174 ASP R CG    1 
ATOM   1315 O OD1   . ASP A 1 199 ? 109.521 104.864 154.814 1.00 40.62  ? 174 ASP R OD1   1 
ATOM   1316 O OD2   . ASP A 1 199 ? 110.609 103.970 156.496 1.00 40.62  ? 174 ASP R OD2   1 
ATOM   1317 N N     . TYR A 1 200 ? 110.130 106.369 153.093 1.00 37.55  ? 175 TYR R N     1 
ATOM   1318 C CA    . TYR A 1 200 ? 110.542 106.155 151.710 1.00 37.55  ? 175 TYR R CA    1 
ATOM   1319 C C     . TYR A 1 200 ? 110.504 107.461 150.928 1.00 37.55  ? 175 TYR R C     1 
ATOM   1320 O O     . TYR A 1 200 ? 111.465 107.816 150.236 1.00 37.55  ? 175 TYR R O     1 
ATOM   1321 C CB    . TYR A 1 200 ? 109.640 105.107 151.055 1.00 37.55  ? 175 TYR R CB    1 
ATOM   1322 C CG    . TYR A 1 200 ? 109.642 105.150 149.543 1.00 37.55  ? 175 TYR R CG    1 
ATOM   1323 C CD1   . TYR A 1 200 ? 110.587 104.444 148.811 1.00 37.55  ? 175 TYR R CD1   1 
ATOM   1324 C CD2   . TYR A 1 200 ? 108.699 105.894 148.848 1.00 37.55  ? 175 TYR R CD2   1 
ATOM   1325 C CE1   . TYR A 1 200 ? 110.594 104.478 147.432 1.00 37.55  ? 175 TYR R CE1   1 
ATOM   1326 C CE2   . TYR A 1 200 ? 108.700 105.936 147.468 1.00 37.55  ? 175 TYR R CE2   1 
ATOM   1327 C CZ    . TYR A 1 200 ? 109.649 105.225 146.765 1.00 37.55  ? 175 TYR R CZ    1 
ATOM   1328 O OH    . TYR A 1 200 ? 109.658 105.261 145.390 1.00 37.55  ? 175 TYR R OH    1 
ATOM   1329 N N     . MET A 1 201 ? 109.396 108.197 151.034 1.00 35.18  ? 176 MET R N     1 
ATOM   1330 C CA    . MET A 1 201 ? 109.257 109.447 150.299 1.00 35.18  ? 176 MET R CA    1 
ATOM   1331 C C     . MET A 1 201 ? 110.259 110.499 150.749 1.00 35.18  ? 176 MET R C     1 
ATOM   1332 O O     . MET A 1 201 ? 110.599 111.392 149.965 1.00 35.18  ? 176 MET R O     1 
ATOM   1333 C CB    . MET A 1 201 ? 107.839 109.993 150.463 1.00 35.18  ? 176 MET R CB    1 
ATOM   1334 C CG    . MET A 1 201 ? 106.780 109.160 149.776 1.00 35.18  ? 176 MET R CG    1 
ATOM   1335 S SD    . MET A 1 201 ? 106.817 109.360 147.989 1.00 35.18  ? 176 MET R SD    1 
ATOM   1336 C CE    . MET A 1 201 ? 105.903 110.886 147.808 1.00 35.18  ? 176 MET R CE    1 
ATOM   1337 N N     . VAL A 1 202 ? 110.740 110.422 151.987 1.00 36.29  ? 177 VAL R N     1 
ATOM   1338 C CA    . VAL A 1 202 ? 111.630 111.450 152.516 1.00 36.29  ? 177 VAL R CA    1 
ATOM   1339 C C     . VAL A 1 202 ? 113.079 111.093 152.212 1.00 36.29  ? 177 VAL R C     1 
ATOM   1340 O O     . VAL A 1 202 ? 113.783 111.842 151.527 1.00 36.29  ? 177 VAL R O     1 
ATOM   1341 C CB    . VAL A 1 202 ? 111.415 111.639 154.029 1.00 36.29  ? 177 VAL R CB    1 
ATOM   1342 C CG1   . VAL A 1 202 ? 112.611 112.343 154.660 1.00 36.29  ? 177 VAL R CG1   1 
ATOM   1343 C CG2   . VAL A 1 202 ? 110.135 112.417 154.285 1.00 36.29  ? 177 VAL R CG2   1 
ATOM   1344 N N     . TYR A 1 203 ? 113.538 109.949 152.723 1.00 37.91  ? 178 TYR R N     1 
ATOM   1345 C CA    . TYR A 1 203 ? 114.951 109.606 152.605 1.00 37.91  ? 178 TYR R CA    1 
ATOM   1346 C C     . TYR A 1 203 ? 115.317 109.142 151.201 1.00 37.91  ? 178 TYR R C     1 
ATOM   1347 O O     . TYR A 1 203 ? 116.413 109.449 150.719 1.00 37.91  ? 178 TYR R O     1 
ATOM   1348 C CB    . TYR A 1 203 ? 115.312 108.526 153.624 1.00 37.91  ? 178 TYR R CB    1 
ATOM   1349 C CG    . TYR A 1 203 ? 115.315 109.011 155.057 1.00 37.91  ? 178 TYR R CG    1 
ATOM   1350 C CD1   . TYR A 1 203 ? 116.030 110.142 155.427 1.00 37.91  ? 178 TYR R CD1   1 
ATOM   1351 C CD2   . TYR A 1 203 ? 114.599 108.340 156.038 1.00 37.91  ? 178 TYR R CD2   1 
ATOM   1352 C CE1   . TYR A 1 203 ? 116.035 110.589 156.734 1.00 37.91  ? 178 TYR R CE1   1 
ATOM   1353 C CE2   . TYR A 1 203 ? 114.598 108.779 157.348 1.00 37.91  ? 178 TYR R CE2   1 
ATOM   1354 C CZ    . TYR A 1 203 ? 115.317 109.904 157.690 1.00 37.91  ? 178 TYR R CZ    1 
ATOM   1355 O OH    . TYR A 1 203 ? 115.320 110.347 158.993 1.00 37.91  ? 178 TYR R OH    1 
ATOM   1356 N N     . PHE A 1 204 ? 114.429 108.406 150.532 1.00 35.44  ? 179 PHE R N     1 
ATOM   1357 C CA    . PHE A 1 204 ? 114.757 107.829 149.232 1.00 35.44  ? 179 PHE R CA    1 
ATOM   1358 C C     . PHE A 1 204 ? 114.311 108.726 148.081 1.00 35.44  ? 179 PHE R C     1 
ATOM   1359 O O     . PHE A 1 204 ? 115.130 109.136 147.253 1.00 35.44  ? 179 PHE R O     1 
ATOM   1360 C CB    . PHE A 1 204 ? 114.124 106.440 149.097 1.00 35.44  ? 179 PHE R CB    1 
ATOM   1361 C CG    . PHE A 1 204 ? 114.691 105.625 147.968 1.00 35.44  ? 179 PHE R CG    1 
ATOM   1362 C CD1   . PHE A 1 204 ? 116.035 105.298 147.938 1.00 35.44  ? 179 PHE R CD1   1 
ATOM   1363 C CD2   . PHE A 1 204 ? 113.880 105.193 146.934 1.00 35.44  ? 179 PHE R CD2   1 
ATOM   1364 C CE1   . PHE A 1 204 ? 116.558 104.551 146.901 1.00 35.44  ? 179 PHE R CE1   1 
ATOM   1365 C CE2   . PHE A 1 204 ? 114.398 104.447 145.895 1.00 35.44  ? 179 PHE R CE2   1 
ATOM   1366 C CZ    . PHE A 1 204 ? 115.738 104.126 145.878 1.00 35.44  ? 179 PHE R CZ    1 
ATOM   1367 N N     . SER A 1 205 ? 113.016 109.037 148.014 1.00 31.88  ? 180 SER R N     1 
ATOM   1368 C CA    . SER A 1 205 ? 112.507 109.796 146.878 1.00 31.88  ? 180 SER R CA    1 
ATOM   1369 C C     . SER A 1 205 ? 113.063 111.213 146.869 1.00 31.88  ? 180 SER R C     1 
ATOM   1370 O O     . SER A 1 205 ? 113.820 111.589 145.967 1.00 31.88  ? 180 SER R O     1 
ATOM   1371 C CB    . SER A 1 205 ? 110.979 109.822 146.909 1.00 31.88  ? 180 SER R CB    1 
ATOM   1372 O OG    . SER A 1 205 ? 110.463 110.592 145.839 1.00 31.88  ? 180 SER R OG    1 
ATOM   1373 N N     . PHE A 1 206 ? 112.725 112.008 147.882 1.00 30.88  ? 181 PHE R N     1 
ATOM   1374 C CA    . PHE A 1 206 ? 113.094 113.416 147.889 1.00 30.88  ? 181 PHE R CA    1 
ATOM   1375 C C     . PHE A 1 206 ? 114.593 113.656 147.983 1.00 30.88  ? 181 PHE R C     1 
ATOM   1376 O O     . PHE A 1 206 ? 115.136 114.405 147.163 1.00 30.88  ? 181 PHE R O     1 
ATOM   1377 C CB    . PHE A 1 206 ? 112.408 114.138 149.051 1.00 30.88  ? 181 PHE R CB    1 
ATOM   1378 C CG    . PHE A 1 206 ? 112.911 115.535 149.271 1.00 30.88  ? 181 PHE R CG    1 
ATOM   1379 C CD1   . PHE A 1 206 ? 112.934 116.450 148.233 1.00 30.88  ? 181 PHE R CD1   1 
ATOM   1380 C CD2   . PHE A 1 206 ? 113.361 115.934 150.517 1.00 30.88  ? 181 PHE R CD2   1 
ATOM   1381 C CE1   . PHE A 1 206 ? 113.396 117.735 148.434 1.00 30.88  ? 181 PHE R CE1   1 
ATOM   1382 C CE2   . PHE A 1 206 ? 113.824 117.217 150.724 1.00 30.88  ? 181 PHE R CE2   1 
ATOM   1383 C CZ    . PHE A 1 206 ? 113.841 118.118 149.681 1.00 30.88  ? 181 PHE R CZ    1 
ATOM   1384 N N     . PHE A 1 207 ? 115.275 113.041 148.945 1.00 33.16  ? 182 PHE R N     1 
ATOM   1385 C CA    . PHE A 1 207 ? 116.679 113.339 149.193 1.00 33.16  ? 182 PHE R CA    1 
ATOM   1386 C C     . PHE A 1 207 ? 117.606 112.811 148.110 1.00 33.16  ? 182 PHE R C     1 
ATOM   1387 O O     . PHE A 1 207 ? 118.734 113.299 147.988 1.00 33.16  ? 182 PHE R O     1 
ATOM   1388 C CB    . PHE A 1 207 ? 117.110 112.759 150.545 1.00 33.16  ? 182 PHE R CB    1 
ATOM   1389 C CG    . PHE A 1 207 ? 118.599 112.712 150.737 1.00 33.16  ? 182 PHE R CG    1 
ATOM   1390 C CD1   . PHE A 1 207 ? 119.330 113.881 150.861 1.00 33.16  ? 182 PHE R CD1   1 
ATOM   1391 C CD2   . PHE A 1 207 ? 119.267 111.501 150.786 1.00 33.16  ? 182 PHE R CD2   1 
ATOM   1392 C CE1   . PHE A 1 207 ? 120.699 113.843 151.034 1.00 33.16  ? 182 PHE R CE1   1 
ATOM   1393 C CE2   . PHE A 1 207 ? 120.638 111.456 150.959 1.00 33.16  ? 182 PHE R CE2   1 
ATOM   1394 C CZ    . PHE A 1 207 ? 121.354 112.630 151.084 1.00 33.16  ? 182 PHE R CZ    1 
ATOM   1395 N N     . LEU A 1 208 ? 117.161 111.842 147.313 1.00 31.03  ? 183 LEU R N     1 
ATOM   1396 C CA    . LEU A 1 208 ? 118.030 111.167 146.357 1.00 31.03  ? 183 LEU R CA    1 
ATOM   1397 C C     . LEU A 1 208 ? 117.659 111.446 144.905 1.00 31.03  ? 183 LEU R C     1 
ATOM   1398 O O     . LEU A 1 208 ? 118.537 111.439 144.038 1.00 31.03  ? 183 LEU R O     1 
ATOM   1399 C CB    . LEU A 1 208 ? 118.007 109.655 146.615 1.00 31.03  ? 183 LEU R CB    1 
ATOM   1400 C CG    . LEU A 1 208 ? 119.279 108.860 146.306 1.00 31.03  ? 183 LEU R CG    1 
ATOM   1401 C CD1   . LEU A 1 208 ? 120.500 109.455 146.999 1.00 31.03  ? 183 LEU R CD1   1 
ATOM   1402 C CD2   . LEU A 1 208 ? 119.097 107.401 146.697 1.00 31.03  ? 183 LEU R CD2   1 
ATOM   1403 N N     . TRP A 1 209 ? 116.381 111.692 144.614 1.00 27.61  ? 184 TRP R N     1 
ATOM   1404 C CA    . TRP A 1 209 ? 115.912 111.813 143.240 1.00 27.61  ? 184 TRP R CA    1 
ATOM   1405 C C     . TRP A 1 209 ? 115.152 113.109 142.983 1.00 27.61  ? 184 TRP R C     1 
ATOM   1406 O O     . TRP A 1 209 ? 114.648 113.306 141.872 1.00 27.61  ? 184 TRP R O     1 
ATOM   1407 C CB    . TRP A 1 209 ? 115.037 110.610 142.888 1.00 27.61  ? 184 TRP R CB    1 
ATOM   1408 C CG    . TRP A 1 209 ? 115.764 109.309 143.032 1.00 27.61  ? 184 TRP R CG    1 
ATOM   1409 C CD1   . TRP A 1 209 ? 115.630 108.406 144.045 1.00 27.61  ? 184 TRP R CD1   1 
ATOM   1410 C CD2   . TRP A 1 209 ? 116.750 108.771 142.144 1.00 27.61  ? 184 TRP R CD2   1 
ATOM   1411 N NE1   . TRP A 1 209 ? 116.467 107.337 143.841 1.00 27.61  ? 184 TRP R NE1   1 
ATOM   1412 C CE2   . TRP A 1 209 ? 117.167 107.537 142.681 1.00 27.61  ? 184 TRP R CE2   1 
ATOM   1413 C CE3   . TRP A 1 209 ? 117.320 109.211 140.946 1.00 27.61  ? 184 TRP R CE3   1 
ATOM   1414 C CZ2   . TRP A 1 209 ? 118.123 106.739 142.061 1.00 27.61  ? 184 TRP R CZ2   1 
ATOM   1415 C CZ3   . TRP A 1 209 ? 118.270 108.418 140.333 1.00 27.61  ? 184 TRP R CZ3   1 
ATOM   1416 C CH2   . TRP A 1 209 ? 118.662 107.196 140.891 1.00 27.61  ? 184 TRP R CH2   1 
ATOM   1417 N N     . ILE A 1 210 ? 115.047 113.989 143.977 1.00 27.83  ? 185 ILE R N     1 
ATOM   1418 C CA    . ILE A 1 210 ? 114.433 115.299 143.786 1.00 27.83  ? 185 ILE R CA    1 
ATOM   1419 C C     . ILE A 1 210 ? 115.438 116.373 144.179 1.00 27.83  ? 185 ILE R C     1 
ATOM   1420 O O     . ILE A 1 210 ? 115.623 117.360 143.459 1.00 27.83  ? 185 ILE R O     1 
ATOM   1421 C CB    . ILE A 1 210 ? 113.133 115.442 144.597 1.00 27.83  ? 185 ILE R CB    1 
ATOM   1422 C CG1   . ILE A 1 210 ? 112.076 114.464 144.078 1.00 27.83  ? 185 ILE R CG1   1 
ATOM   1423 C CG2   . ILE A 1 210 ? 112.621 116.876 144.520 1.00 27.83  ? 185 ILE R CG2   1 
ATOM   1424 C CD1   . ILE A 1 210 ? 110.781 114.479 144.865 1.00 27.83  ? 185 ILE R CD1   1 
ATOM   1425 N N     . LEU A 1 211 ? 116.088 116.190 145.329 1.00 27.74  ? 186 LEU R N     1 
ATOM   1426 C CA    . LEU A 1 211 ? 117.057 117.175 145.798 1.00 27.74  ? 186 LEU R CA    1 
ATOM   1427 C C     . LEU A 1 211 ? 118.352 117.101 144.999 1.00 27.74  ? 186 LEU R C     1 
ATOM   1428 O O     . LEU A 1 211 ? 118.933 118.134 144.644 1.00 27.74  ? 186 LEU R O     1 
ATOM   1429 C CB    . LEU A 1 211 ? 117.333 116.966 147.287 1.00 27.74  ? 186 LEU R CB    1 
ATOM   1430 C CG    . LEU A 1 211 ? 118.040 118.108 148.022 1.00 27.74  ? 186 LEU R CG    1 
ATOM   1431 C CD1   . LEU A 1 211 ? 117.226 119.391 147.965 1.00 27.74  ? 186 LEU R CD1   1 
ATOM   1432 C CD2   . LEU A 1 211 ? 118.320 117.716 149.464 1.00 27.74  ? 186 LEU R CD2   1 
ATOM   1433 N N     . VAL A 1 212 ? 118.831 115.893 144.723 1.00 26.29  ? 187 VAL R N     1 
ATOM   1434 C CA    . VAL A 1 212 ? 120.101 115.713 144.022 1.00 26.29  ? 187 VAL R CA    1 
ATOM   1435 C C     . VAL A 1 212 ? 119.996 116.313 142.623 1.00 26.29  ? 187 VAL R C     1 
ATOM   1436 O O     . VAL A 1 212 ? 120.899 117.053 142.210 1.00 26.29  ? 187 VAL R O     1 
ATOM   1437 C CB    . VAL A 1 212 ? 120.512 114.232 143.977 1.00 26.29  ? 187 VAL R CB    1 
ATOM   1438 C CG1   . VAL A 1 212 ? 121.726 114.044 143.081 1.00 26.29  ? 187 VAL R CG1   1 
ATOM   1439 C CG2   . VAL A 1 212 ? 120.805 113.729 145.378 1.00 26.29  ? 187 VAL R CG2   1 
ATOM   1440 N N     . PRO A 1 213 ? 118.934 116.033 141.855 1.00 25.23  ? 188 PRO R N     1 
ATOM   1441 C CA    . PRO A 1 213 ? 118.780 116.718 140.566 1.00 25.23  ? 188 PRO R CA    1 
ATOM   1442 C C     . PRO A 1 213 ? 118.800 118.232 140.702 1.00 25.23  ? 188 PRO R C     1 
ATOM   1443 O O     . PRO A 1 213 ? 119.418 118.921 139.889 1.00 25.23  ? 188 PRO R O     1 
ATOM   1444 C CB    . PRO A 1 213 ? 117.420 116.219 140.067 1.00 25.23  ? 188 PRO R CB    1 
ATOM   1445 C CG    . PRO A 1 213 ? 117.288 114.879 140.658 1.00 25.23  ? 188 PRO R CG    1 
ATOM   1446 C CD    . PRO A 1 213 ? 117.938 114.957 142.013 1.00 25.23  ? 188 PRO R CD    1 
ATOM   1447 N N     . LEU A 1 214 ? 118.145 118.765 141.734 1.00 24.89  ? 189 LEU R N     1 
ATOM   1448 C CA    . LEU A 1 214 ? 118.091 120.214 141.890 1.00 24.89  ? 189 LEU R CA    1 
ATOM   1449 C C     . LEU A 1 214 ? 119.476 120.796 142.142 1.00 24.89  ? 189 LEU R C     1 
ATOM   1450 O O     . LEU A 1 214 ? 119.862 121.792 141.518 1.00 24.89  ? 189 LEU R O     1 
ATOM   1451 C CB    . LEU A 1 214 ? 117.137 120.582 143.026 1.00 24.89  ? 189 LEU R CB    1 
ATOM   1452 C CG    . LEU A 1 214 ? 116.892 122.071 143.289 1.00 24.89  ? 189 LEU R CG    1 
ATOM   1453 C CD1   . LEU A 1 214 ? 116.755 122.868 141.997 1.00 24.89  ? 189 LEU R CD1   1 
ATOM   1454 C CD2   . LEU A 1 214 ? 115.655 122.246 144.155 1.00 24.89  ? 189 LEU R CD2   1 
ATOM   1455 N N     . VAL A 1 215 ? 120.245 120.181 143.041 1.00 25.82  ? 190 VAL R N     1 
ATOM   1456 C CA    . VAL A 1 215 ? 121.571 120.704 143.362 1.00 25.82  ? 190 VAL R CA    1 
ATOM   1457 C C     . VAL A 1 215 ? 122.488 120.616 142.149 1.00 25.82  ? 190 VAL R C     1 
ATOM   1458 O O     . VAL A 1 215 ? 123.250 121.549 141.854 1.00 25.82  ? 190 VAL R O     1 
ATOM   1459 C CB    . VAL A 1 215 ? 122.160 119.957 144.571 1.00 25.82  ? 190 VAL R CB    1 
ATOM   1460 C CG1   . VAL A 1 215 ? 123.580 120.426 144.845 1.00 25.82  ? 190 VAL R CG1   1 
ATOM   1461 C CG2   . VAL A 1 215 ? 121.286 120.163 145.796 1.00 25.82  ? 190 VAL R CG2   1 
ATOM   1462 N N     . VAL A 1 216 ? 122.441 119.491 141.433 1.00 23.90  ? 191 VAL R N     1 
ATOM   1463 C CA    . VAL A 1 216 ? 123.333 119.321 140.293 1.00 23.90  ? 191 VAL R CA    1 
ATOM   1464 C C     . VAL A 1 216 ? 122.958 120.285 139.175 1.00 23.90  ? 191 VAL R C     1 
ATOM   1465 O O     . VAL A 1 216 ? 123.835 120.853 138.518 1.00 23.90  ? 191 VAL R O     1 
ATOM   1466 C CB    . VAL A 1 216 ? 123.339 117.855 139.818 1.00 23.90  ? 191 VAL R CB    1 
ATOM   1467 C CG1   . VAL A 1 216 ? 122.050 117.499 139.101 1.00 23.90  ? 191 VAL R CG1   1 
ATOM   1468 C CG2   . VAL A 1 216 ? 124.542 117.595 138.925 1.00 23.90  ? 191 VAL R CG2   1 
ATOM   1469 N N     . MET A 1 217 ? 121.660 120.505 138.944 1.00 23.72  ? 192 MET R N     1 
ATOM   1470 C CA    . MET A 1 217 ? 121.257 121.505 137.961 1.00 23.72  ? 192 MET R CA    1 
ATOM   1471 C C     . MET A 1 217 ? 121.693 122.900 138.384 1.00 23.72  ? 192 MET R C     1 
ATOM   1472 O O     . MET A 1 217 ? 122.094 123.713 137.544 1.00 23.72  ? 192 MET R O     1 
ATOM   1473 C CB    . MET A 1 217 ? 119.744 121.464 137.741 1.00 23.72  ? 192 MET R CB    1 
ATOM   1474 C CG    . MET A 1 217 ? 119.225 120.135 137.222 1.00 23.72  ? 192 MET R CG    1 
ATOM   1475 S SD    . MET A 1 217 ? 117.438 119.963 137.382 1.00 23.72  ? 192 MET R SD    1 
ATOM   1476 C CE    . MET A 1 217 ? 116.876 121.525 136.712 1.00 23.72  ? 192 MET R CE    1 
ATOM   1477 N N     . CYS A 1 218 ? 121.615 123.203 139.678 1.00 25.75  ? 193 CYS R N     1 
ATOM   1478 C CA    . CYS A 1 218 ? 122.079 124.492 140.176 1.00 25.75  ? 193 CYS R CA    1 
ATOM   1479 C C     . CYS A 1 218 ? 123.547 124.693 139.827 1.00 25.75  ? 193 CYS R C     1 
ATOM   1480 O O     . CYS A 1 218 ? 123.926 125.724 139.256 1.00 25.75  ? 193 CYS R O     1 
ATOM   1481 C CB    . CYS A 1 218 ? 121.875 124.584 141.690 1.00 25.75  ? 193 CYS R CB    1 
ATOM   1482 S SG    . CYS A 1 218 ? 121.791 126.272 142.331 1.00 25.75  ? 193 CYS R SG    1 
ATOM   1483 N N     . ALA A 1 219 ? 124.377 123.705 140.165 1.00 24.58  ? 194 ALA R N     1 
ATOM   1484 C CA    . ALA A 1 219 ? 125.807 123.810 139.887 1.00 24.58  ? 194 ALA R CA    1 
ATOM   1485 C C     . ALA A 1 219 ? 126.068 123.911 138.388 1.00 24.58  ? 194 ALA R C     1 
ATOM   1486 O O     . ALA A 1 219 ? 126.895 124.715 137.937 1.00 24.58  ? 194 ALA R O     1 
ATOM   1487 C CB    . ALA A 1 219 ? 126.543 122.610 140.483 1.00 24.58  ? 194 ALA R CB    1 
ATOM   1488 N N     . ILE A 1 220 ? 125.363 123.098 137.599 1.00 23.91  ? 195 ILE R N     1 
ATOM   1489 C CA    . ILE A 1 220 ? 125.533 123.102 136.148 1.00 23.91  ? 195 ILE R CA    1 
ATOM   1490 C C     . ILE A 1 220 ? 125.228 124.478 135.574 1.00 23.91  ? 195 ILE R C     1 
ATOM   1491 O O     . ILE A 1 220 ? 125.987 125.013 134.761 1.00 23.91  ? 195 ILE R O     1 
ATOM   1492 C CB    . ILE A 1 220 ? 124.647 122.023 135.503 1.00 23.91  ? 195 ILE R CB    1 
ATOM   1493 C CG1   . ILE A 1 220 ? 125.158 120.626 135.872 1.00 23.91  ? 195 ILE R CG1   1 
ATOM   1494 C CG2   . ILE A 1 220 ? 124.548 122.242 134.008 1.00 23.91  ? 195 ILE R CG2   1 
ATOM   1495 C CD1   . ILE A 1 220 ? 124.212 119.505 135.502 1.00 23.91  ? 195 ILE R CD1   1 
ATOM   1496 N N     . TYR A 1 221 ? 124.103 125.065 135.978 1.00 24.37  ? 196 TYR R N     1 
ATOM   1497 C CA    . TYR A 1 221 ? 123.713 126.350 135.413 1.00 24.37  ? 196 TYR R CA    1 
ATOM   1498 C C     . TYR A 1 221 ? 124.626 127.467 135.891 1.00 24.37  ? 196 TYR R C     1 
ATOM   1499 O O     . TYR A 1 221 ? 124.927 128.391 135.126 1.00 24.37  ? 196 TYR R O     1 
ATOM   1500 C CB    . TYR A 1 221 ? 122.254 126.650 135.760 1.00 24.37  ? 196 TYR R CB    1 
ATOM   1501 C CG    . TYR A 1 221 ? 121.242 125.841 134.966 1.00 24.37  ? 196 TYR R CG    1 
ATOM   1502 C CD1   . TYR A 1 221 ? 121.603 125.166 133.805 1.00 24.37  ? 196 TYR R CD1   1 
ATOM   1503 C CD2   . TYR A 1 221 ? 119.924 125.753 135.382 1.00 24.37  ? 196 TYR R CD2   1 
ATOM   1504 C CE1   . TYR A 1 221 ? 120.683 124.434 133.087 1.00 24.37  ? 196 TYR R CE1   1 
ATOM   1505 C CE2   . TYR A 1 221 ? 118.997 125.022 134.669 1.00 24.37  ? 196 TYR R CE2   1 
ATOM   1506 C CZ    . TYR A 1 221 ? 119.382 124.364 133.523 1.00 24.37  ? 196 TYR R CZ    1 
ATOM   1507 O OH    . TYR A 1 221 ? 118.462 123.634 132.808 1.00 24.37  ? 196 TYR R OH    1 
ATOM   1508 N N     . PHE A 1 222 ? 125.096 127.398 137.137 1.00 30.03  ? 197 PHE R N     1 
ATOM   1509 C CA    . PHE A 1 222 ? 126.069 128.381 137.602 1.00 30.03  ? 197 PHE R CA    1 
ATOM   1510 C C     . PHE A 1 222 ? 127.339 128.318 136.760 1.00 30.03  ? 197 PHE R C     1 
ATOM   1511 O O     . PHE A 1 222 ? 127.861 129.349 136.314 1.00 30.03  ? 197 PHE R O     1 
ATOM   1512 C CB    . PHE A 1 222 ? 126.383 128.145 139.080 1.00 30.03  ? 197 PHE R CB    1 
ATOM   1513 C CG    . PHE A 1 222 ? 127.481 129.017 139.613 1.00 30.03  ? 197 PHE R CG    1 
ATOM   1514 C CD1   . PHE A 1 222 ? 127.369 130.397 139.573 1.00 30.03  ? 197 PHE R CD1   1 
ATOM   1515 C CD2   . PHE A 1 222 ? 128.626 128.458 140.155 1.00 30.03  ? 197 PHE R CD2   1 
ATOM   1516 C CE1   . PHE A 1 222 ? 128.379 131.202 140.062 1.00 30.03  ? 197 PHE R CE1   1 
ATOM   1517 C CE2   . PHE A 1 222 ? 129.638 129.259 140.646 1.00 30.03  ? 197 PHE R CE2   1 
ATOM   1518 C CZ    . PHE A 1 222 ? 129.514 130.632 140.600 1.00 30.03  ? 197 PHE R CZ    1 
ATOM   1519 N N     . ASP A 1 223 ? 127.842 127.105 136.516 1.00 28.95  ? 198 ASP R N     1 
ATOM   1520 C CA    . ASP A 1 223 ? 129.047 126.954 135.707 1.00 28.95  ? 198 ASP R CA    1 
ATOM   1521 C C     . ASP A 1 223 ? 128.810 127.412 134.272 1.00 28.95  ? 198 ASP R C     1 
ATOM   1522 O O     . ASP A 1 223 ? 129.690 128.019 133.650 1.00 28.95  ? 198 ASP R O     1 
ATOM   1523 C CB    . ASP A 1 223 ? 129.515 125.499 135.735 1.00 28.95  ? 198 ASP R CB    1 
ATOM   1524 C CG    . ASP A 1 223 ? 131.003 125.362 135.499 1.00 28.95  ? 198 ASP R CG    1 
ATOM   1525 O OD1   . ASP A 1 223 ? 131.503 125.931 134.508 1.00 28.95  ? 198 ASP R OD1   1 
ATOM   1526 O OD2   . ASP A 1 223 ? 131.675 124.685 136.306 1.00 28.95  ? 198 ASP R OD2   1 
ATOM   1527 N N     . ILE A 1 224 ? 127.629 127.118 133.725 1.00 27.40  ? 199 ILE R N     1 
ATOM   1528 C CA    . ILE A 1 224 ? 127.305 127.526 132.359 1.00 27.40  ? 199 ILE R CA    1 
ATOM   1529 C C     . ILE A 1 224 ? 127.316 129.044 132.252 1.00 27.40  ? 199 ILE R C     1 
ATOM   1530 O O     . ILE A 1 224 ? 127.866 129.619 131.305 1.00 27.40  ? 199 ILE R O     1 
ATOM   1531 C CB    . ILE A 1 224 ? 125.944 126.947 131.933 1.00 27.40  ? 199 ILE R CB    1 
ATOM   1532 C CG1   . ILE A 1 224 ? 126.088 125.467 131.575 1.00 27.40  ? 199 ILE R CG1   1 
ATOM   1533 C CG2   . ILE A 1 224 ? 125.369 127.739 130.760 1.00 27.40  ? 199 ILE R CG2   1 
ATOM   1534 C CD1   . ILE A 1 224 ? 124.771 124.772 131.305 1.00 27.40  ? 199 ILE R CD1   1 
ATOM   1535 N N     . PHE A 1 225 ? 126.686 129.715 133.219 1.00 31.82  ? 200 PHE R N     1 
ATOM   1536 C CA    . PHE A 1 225 ? 126.677 131.173 133.206 1.00 31.82  ? 200 PHE R CA    1 
ATOM   1537 C C     . PHE A 1 225 ? 128.088 131.726 133.340 1.00 31.82  ? 200 PHE R C     1 
ATOM   1538 O O     . PHE A 1 225 ? 128.454 132.684 132.650 1.00 31.82  ? 200 PHE R O     1 
ATOM   1539 C CB    . PHE A 1 225 ? 125.786 131.712 134.322 1.00 31.82  ? 200 PHE R CB    1 
ATOM   1540 C CG    . PHE A 1 225 ? 125.647 133.208 134.311 1.00 31.82  ? 200 PHE R CG    1 
ATOM   1541 C CD1   . PHE A 1 225 ? 125.075 133.854 133.229 1.00 31.82  ? 200 PHE R CD1   1 
ATOM   1542 C CD2   . PHE A 1 225 ? 126.100 133.969 135.375 1.00 31.82  ? 200 PHE R CD2   1 
ATOM   1543 C CE1   . PHE A 1 225 ? 124.950 135.229 133.213 1.00 31.82  ? 200 PHE R CE1   1 
ATOM   1544 C CE2   . PHE A 1 225 ? 125.978 135.343 135.362 1.00 31.82  ? 200 PHE R CE2   1 
ATOM   1545 C CZ    . PHE A 1 225 ? 125.402 135.973 134.280 1.00 31.82  ? 200 PHE R CZ    1 
ATOM   1546 N N     . TYR A 1 226 ? 128.899 131.131 134.216 1.00 33.84  ? 201 TYR R N     1 
ATOM   1547 C CA    . TYR A 1 226 ? 130.278 131.584 134.362 1.00 33.84  ? 201 TYR R CA    1 
ATOM   1548 C C     . TYR A 1 226 ? 131.032 131.469 133.042 1.00 33.84  ? 201 TYR R C     1 
ATOM   1549 O O     . TYR A 1 226 ? 131.721 132.405 132.620 1.00 33.84  ? 201 TYR R O     1 
ATOM   1550 C CB    . TYR A 1 226 ? 130.979 130.775 135.454 1.00 33.84  ? 201 TYR R CB    1 
ATOM   1551 C CG    . TYR A 1 226 ? 132.482 130.729 135.308 1.00 33.84  ? 201 TYR R CG    1 
ATOM   1552 C CD1   . TYR A 1 226 ? 133.256 131.860 135.531 1.00 33.84  ? 201 TYR R CD1   1 
ATOM   1553 C CD2   . TYR A 1 226 ? 133.128 129.555 134.946 1.00 33.84  ? 201 TYR R CD2   1 
ATOM   1554 C CE1   . TYR A 1 226 ? 134.630 131.823 135.398 1.00 33.84  ? 201 TYR R CE1   1 
ATOM   1555 C CE2   . TYR A 1 226 ? 134.502 129.507 134.811 1.00 33.84  ? 201 TYR R CE2   1 
ATOM   1556 C CZ    . TYR A 1 226 ? 135.248 130.644 135.038 1.00 33.84  ? 201 TYR R CZ    1 
ATOM   1557 O OH    . TYR A 1 226 ? 136.617 130.602 134.905 1.00 33.84  ? 201 TYR R OH    1 
ATOM   1558 N N     . ILE A 1 227 ? 130.897 130.326 132.366 1.00 30.14  ? 202 ILE R N     1 
ATOM   1559 C CA    . ILE A 1 227 ? 131.635 130.103 131.125 1.00 30.14  ? 202 ILE R CA    1 
ATOM   1560 C C     . ILE A 1 227 ? 131.166 131.069 130.043 1.00 30.14  ? 202 ILE R C     1 
ATOM   1561 O O     . ILE A 1 227 ? 131.979 131.668 129.328 1.00 30.14  ? 202 ILE R O     1 
ATOM   1562 C CB    . ILE A 1 227 ? 131.495 128.640 130.668 1.00 30.14  ? 202 ILE R CB    1 
ATOM   1563 C CG1   . ILE A 1 227 ? 132.140 127.697 131.685 1.00 30.14  ? 202 ILE R CG1   1 
ATOM   1564 C CG2   . ILE A 1 227 ? 132.130 128.453 129.298 1.00 30.14  ? 202 ILE R CG2   1 
ATOM   1565 C CD1   . ILE A 1 227 ? 131.667 126.263 131.569 1.00 30.14  ? 202 ILE R CD1   1 
ATOM   1566 N N     . ILE A 1 228 ? 129.849 131.231 129.898 1.00 32.76  ? 203 ILE R N     1 
ATOM   1567 C CA    . ILE A 1 228 ? 129.334 132.095 128.837 1.00 32.76  ? 203 ILE R CA    1 
ATOM   1568 C C     . ILE A 1 228 ? 129.718 133.545 129.098 1.00 32.76  ? 203 ILE R C     1 
ATOM   1569 O O     . ILE A 1 228 ? 129.988 134.308 128.162 1.00 32.76  ? 203 ILE R O     1 
ATOM   1570 C CB    . ILE A 1 228 ? 127.810 131.925 128.689 1.00 32.76  ? 203 ILE R CB    1 
ATOM   1571 C CG1   . ILE A 1 228 ? 127.325 132.605 127.407 1.00 32.76  ? 203 ILE R CG1   1 
ATOM   1572 C CG2   . ILE A 1 228 ? 127.085 132.498 129.884 1.00 32.76  ? 203 ILE R CG2   1 
ATOM   1573 C CD1   . ILE A 1 228 ? 125.903 132.251 127.032 1.00 32.76  ? 203 ILE R CD1   1 
ATOM   1574 N N     . ARG A 1 229 ? 129.742 133.956 130.369 1.00 34.59  ? 204 ARG R N     1 
ATOM   1575 C CA    . ARG A 1 229 ? 130.193 135.306 130.691 1.00 34.59  ? 204 ARG R CA    1 
ATOM   1576 C C     . ARG A 1 229 ? 131.671 135.475 130.367 1.00 34.59  ? 204 ARG R C     1 
ATOM   1577 O O     . ARG A 1 229 ? 132.081 136.496 129.802 1.00 34.59  ? 204 ARG R O     1 
ATOM   1578 C CB    . ARG A 1 229 ? 129.925 135.612 132.165 1.00 34.59  ? 204 ARG R CB    1 
ATOM   1579 C CG    . ARG A 1 229 ? 130.471 136.958 132.626 1.00 34.59  ? 204 ARG R CG    1 
ATOM   1580 C CD    . ARG A 1 229 ? 131.787 136.813 133.380 1.00 34.59  ? 204 ARG R CD    1 
ATOM   1581 N NE    . ARG A 1 229 ? 131.658 135.987 134.574 1.00 34.59  ? 204 ARG R NE    1 
ATOM   1582 C CZ    . ARG A 1 229 ? 130.969 136.329 135.655 1.00 34.59  ? 204 ARG R CZ    1 
ATOM   1583 N NH1   . ARG A 1 229 ? 130.351 137.496 135.742 1.00 34.59  ? 204 ARG R NH1   1 
ATOM   1584 N NH2   . ARG A 1 229 ? 130.903 135.481 136.677 1.00 34.59  ? 204 ARG R NH2   1 
ATOM   1585 N N     . ASN A 1 230 ? 132.491 134.482 130.720 1.00 35.61  ? 205 ASN R N     1 
ATOM   1586 C CA    . ASN A 1 230 ? 133.916 134.563 130.425 1.00 35.61  ? 205 ASN R CA    1 
ATOM   1587 C C     . ASN A 1 230 ? 134.188 134.599 128.928 1.00 35.61  ? 205 ASN R C     1 
ATOM   1588 O O     . ASN A 1 230 ? 135.148 135.248 128.500 1.00 35.61  ? 205 ASN R O     1 
ATOM   1589 C CB    . ASN A 1 230 ? 134.648 133.379 131.062 1.00 35.61  ? 205 ASN R CB    1 
ATOM   1590 C CG    . ASN A 1 230 ? 136.156 133.518 130.990 1.00 35.61  ? 205 ASN R CG    1 
ATOM   1591 O OD1   . ASN A 1 230 ? 136.677 134.528 130.517 1.00 35.61  ? 205 ASN R OD1   1 
ATOM   1592 N ND2   . ASN A 1 230 ? 136.866 132.502 131.466 1.00 35.61  ? 205 ASN R ND2   1 
ATOM   1593 N N     . ARG A 1 231 ? 133.370 133.919 128.125 1.00 31.02  ? 206 ARG R N     1 
ATOM   1594 C CA    . ARG A 1 231 ? 133.538 133.933 126.677 1.00 31.02  ? 206 ARG R CA    1 
ATOM   1595 C C     . ARG A 1 231 ? 133.103 135.261 126.066 1.00 31.02  ? 206 ARG R C     1 
ATOM   1596 O O     . ARG A 1 231 ? 133.831 135.840 125.253 1.00 31.02  ? 206 ARG R O     1 
ATOM   1597 C CB    . ARG A 1 231 ? 132.751 132.781 126.045 1.00 31.02  ? 206 ARG R CB    1 
ATOM   1598 C CG    . ARG A 1 231 ? 132.713 132.824 124.527 1.00 31.02  ? 206 ARG R CG    1 
ATOM   1599 C CD    . ARG A 1 231 ? 132.531 131.438 123.932 1.00 31.02  ? 206 ARG R CD    1 
ATOM   1600 N NE    . ARG A 1 231 ? 133.723 130.612 124.094 1.00 31.02  ? 206 ARG R NE    1 
ATOM   1601 C CZ    . ARG A 1 231 ? 134.740 130.581 123.243 1.00 31.02  ? 206 ARG R CZ    1 
ATOM   1602 N NH1   . ARG A 1 231 ? 134.755 131.330 122.153 1.00 31.02  ? 206 ARG R NH1   1 
ATOM   1603 N NH2   . ARG A 1 231 ? 135.770 129.778 123.494 1.00 31.02  ? 206 ARG R NH2   1 
ATOM   1604 N N     . LEU A 1 232 ? 131.930 135.756 126.447 1.00 36.94  ? 207 LEU R N     1 
ATOM   1605 C CA    . LEU A 1 232 ? 131.428 137.020 125.921 1.00 36.94  ? 207 LEU R CA    1 
ATOM   1606 C C     . LEU A 1 232 ? 132.265 138.187 126.432 1.00 36.94  ? 207 LEU R C     1 
ATOM   1607 O O     . LEU A 1 232 ? 133.189 138.643 125.758 1.00 36.94  ? 207 LEU R O     1 
ATOM   1608 C CB    . LEU A 1 232 ? 129.960 137.220 126.305 1.00 36.94  ? 207 LEU R CB    1 
ATOM   1609 C CG    . LEU A 1 232 ? 128.922 136.630 125.348 1.00 36.94  ? 207 LEU R CG    1 
ATOM   1610 C CD1   . LEU A 1 232 ? 127.551 136.593 126.003 1.00 36.94  ? 207 LEU R CD1   1 
ATOM   1611 C CD2   . LEU A 1 232 ? 128.870 137.423 124.051 1.00 36.94  ? 207 LEU R CD2   1 
ATOM   1612 N N     . GLU A 1 249 ? 124.282 139.066 127.968 1.00 44.02  ? 224 GLU R N     1 
ATOM   1613 C CA    . GLU A 1 249 ? 124.529 137.845 128.724 1.00 44.02  ? 224 GLU R CA    1 
ATOM   1614 C C     . GLU A 1 249 ? 123.492 137.659 129.826 1.00 44.02  ? 224 GLU R C     1 
ATOM   1615 O O     . GLU A 1 249 ? 123.392 136.586 130.421 1.00 44.02  ? 224 GLU R O     1 
ATOM   1616 C CB    . GLU A 1 249 ? 125.933 137.862 129.330 1.00 44.02  ? 224 GLU R CB    1 
ATOM   1617 C CG    . GLU A 1 249 ? 126.152 138.968 130.349 1.00 44.02  ? 224 GLU R CG    1 
ATOM   1618 C CD    . GLU A 1 249 ? 127.316 138.683 131.278 1.00 44.02  ? 224 GLU R CD    1 
ATOM   1619 O OE1   . GLU A 1 249 ? 127.922 137.599 131.158 1.00 44.02  ? 224 GLU R OE1   1 
ATOM   1620 O OE2   . GLU A 1 249 ? 127.623 139.544 132.129 1.00 44.02  ? 224 GLU R OE2   1 
ATOM   1621 N N     . PHE A 1 250 ? 122.720 138.714 130.095 1.00 42.67  ? 225 PHE R N     1 
ATOM   1622 C CA    . PHE A 1 250 ? 121.728 138.642 131.163 1.00 42.67  ? 225 PHE R CA    1 
ATOM   1623 C C     . PHE A 1 250 ? 120.479 137.886 130.731 1.00 42.67  ? 225 PHE R C     1 
ATOM   1624 O O     . PHE A 1 250 ? 119.705 137.441 131.584 1.00 42.67  ? 225 PHE R O     1 
ATOM   1625 C CB    . PHE A 1 250 ? 121.366 140.048 131.640 1.00 42.67  ? 225 PHE R CB    1 
ATOM   1626 C CG    . PHE A 1 250 ? 122.500 140.767 132.313 1.00 42.67  ? 225 PHE R CG    1 
ATOM   1627 C CD1   . PHE A 1 250 ? 123.243 140.143 133.300 1.00 42.67  ? 225 PHE R CD1   1 
ATOM   1628 C CD2   . PHE A 1 250 ? 122.823 142.066 131.960 1.00 42.67  ? 225 PHE R CD2   1 
ATOM   1629 C CE1   . PHE A 1 250 ? 124.287 140.799 133.922 1.00 42.67  ? 225 PHE R CE1   1 
ATOM   1630 C CE2   . PHE A 1 250 ? 123.866 142.729 132.579 1.00 42.67  ? 225 PHE R CE2   1 
ATOM   1631 C CZ    . PHE A 1 250 ? 124.599 142.094 133.561 1.00 42.67  ? 225 PHE R CZ    1 
ATOM   1632 N N     . LYS A 1 251 ? 120.259 137.729 129.425 1.00 39.32  ? 226 LYS R N     1 
ATOM   1633 C CA    . LYS A 1 251 ? 119.130 136.926 128.964 1.00 39.32  ? 226 LYS R CA    1 
ATOM   1634 C C     . LYS A 1 251 ? 119.308 135.464 129.357 1.00 39.32  ? 226 LYS R C     1 
ATOM   1635 O O     . LYS A 1 251 ? 118.370 134.813 129.838 1.00 39.32  ? 226 LYS R O     1 
ATOM   1636 C CB    . LYS A 1 251 ? 118.973 137.068 127.450 1.00 39.32  ? 226 LYS R CB    1 
ATOM   1637 C CG    . LYS A 1 251 ? 117.752 136.367 126.881 1.00 39.32  ? 226 LYS R CG    1 
ATOM   1638 C CD    . LYS A 1 251 ? 117.325 136.995 125.565 1.00 39.32  ? 226 LYS R CD    1 
ATOM   1639 C CE    . LYS A 1 251 ? 115.887 136.642 125.225 1.00 39.32  ? 226 LYS R CE    1 
ATOM   1640 N NZ    . LYS A 1 251 ? 115.393 137.407 124.048 1.00 39.32  ? 226 LYS R NZ    1 
ATOM   1641 N N     . THR A 1 252 ? 120.515 134.931 129.160 1.00 35.25  ? 227 THR R N     1 
ATOM   1642 C CA    . THR A 1 252 ? 120.802 133.558 129.560 1.00 35.25  ? 227 THR R CA    1 
ATOM   1643 C C     . THR A 1 252 ? 120.646 133.392 131.066 1.00 35.25  ? 227 THR R C     1 
ATOM   1644 O O     . THR A 1 252 ? 120.097 132.392 131.544 1.00 35.25  ? 227 THR R O     1 
ATOM   1645 C CB    . THR A 1 252 ? 122.214 133.168 129.117 1.00 35.25  ? 227 THR R CB    1 
ATOM   1646 O OG1   . THR A 1 252 ? 122.337 133.342 127.700 1.00 35.25  ? 227 THR R OG1   1 
ATOM   1647 C CG2   . THR A 1 252 ? 122.501 131.719 129.470 1.00 35.25  ? 227 THR R CG2   1 
ATOM   1648 N N     . ALA A 1 253 ? 121.135 134.368 131.833 1.00 31.43  ? 228 ALA R N     1 
ATOM   1649 C CA    . ALA A 1 253 ? 120.998 134.329 133.282 1.00 31.43  ? 228 ALA R CA    1 
ATOM   1650 C C     . ALA A 1 253 ? 119.529 134.318 133.685 1.00 31.43  ? 228 ALA R C     1 
ATOM   1651 O O     . ALA A 1 253 ? 119.120 133.567 134.575 1.00 31.43  ? 228 ALA R O     1 
ATOM   1652 C CB    . ALA A 1 253 ? 121.720 135.527 133.905 1.00 31.43  ? 228 ALA R CB    1 
ATOM   1653 N N     . LYS A 1 254 ? 118.721 135.150 133.027 1.00 31.64  ? 229 LYS R N     1 
ATOM   1654 C CA    . LYS A 1 254 ? 117.293 135.191 133.315 1.00 31.64  ? 229 LYS R CA    1 
ATOM   1655 C C     . LYS A 1 254 ? 116.642 133.842 133.037 1.00 31.64  ? 229 LYS R C     1 
ATOM   1656 O O     . LYS A 1 254 ? 115.841 133.346 133.835 1.00 31.64  ? 229 LYS R O     1 
ATOM   1657 C CB    . LYS A 1 254 ? 116.629 136.293 132.486 1.00 31.64  ? 229 LYS R CB    1 
ATOM   1658 C CG    . LYS A 1 254 ? 115.112 136.196 132.427 1.00 31.64  ? 229 LYS R CG    1 
ATOM   1659 C CD    . LYS A 1 254 ? 114.481 137.530 132.066 1.00 31.64  ? 229 LYS R CD    1 
ATOM   1660 C CE    . LYS A 1 254 ? 112.968 137.420 131.963 1.00 31.64  ? 229 LYS R CE    1 
ATOM   1661 N NZ    . LYS A 1 254 ? 112.334 137.016 133.249 1.00 31.64  ? 229 LYS R NZ    1 
ATOM   1662 N N     . SER A 1 255 ? 116.981 133.230 131.901 1.00 31.03  ? 230 SER R N     1 
ATOM   1663 C CA    . SER A 1 255 ? 116.393 131.937 131.558 1.00 31.03  ? 230 SER R CA    1 
ATOM   1664 C C     . SER A 1 255 ? 116.785 130.865 132.571 1.00 31.03  ? 230 SER R C     1 
ATOM   1665 O O     . SER A 1 255 ? 115.940 130.086 133.036 1.00 31.03  ? 230 SER R O     1 
ATOM   1666 C CB    . SER A 1 255 ? 116.824 131.529 130.149 1.00 31.03  ? 230 SER R CB    1 
ATOM   1667 O OG    . SER A 1 255 ? 116.516 132.543 129.210 1.00 31.03  ? 230 SER R OG    1 
ATOM   1668 N N     . LEU A 1 256 ? 118.071 130.813 132.928 1.00 27.79  ? 231 LEU R N     1 
ATOM   1669 C CA    . LEU A 1 256 ? 118.540 129.812 133.881 1.00 27.79  ? 231 LEU R CA    1 
ATOM   1670 C C     . LEU A 1 256 ? 117.892 130.011 135.246 1.00 27.79  ? 231 LEU R C     1 
ATOM   1671 O O     . LEU A 1 256 ? 117.497 129.045 135.912 1.00 27.79  ? 231 LEU R O     1 
ATOM   1672 C CB    . LEU A 1 256 ? 120.066 129.876 133.995 1.00 27.79  ? 231 LEU R CB    1 
ATOM   1673 C CG    . LEU A 1 256 ? 120.888 129.528 132.747 1.00 27.79  ? 231 LEU R CG    1 
ATOM   1674 C CD1   . LEU A 1 256 ? 122.315 129.174 133.129 1.00 27.79  ? 231 LEU R CD1   1 
ATOM   1675 C CD2   . LEU A 1 256 ? 120.259 128.392 131.954 1.00 27.79  ? 231 LEU R CD2   1 
ATOM   1676 N N     . LEU A 1 257 ? 117.778 131.268 135.681 1.00 26.23  ? 232 LEU R N     1 
ATOM   1677 C CA    . LEU A 1 257 ? 117.134 131.554 136.955 1.00 26.23  ? 232 LEU R CA    1 
ATOM   1678 C C     . LEU A 1 257 ? 115.667 131.155 136.922 1.00 26.23  ? 232 LEU R C     1 
ATOM   1679 O O     . LEU A 1 257 ? 115.145 130.603 137.891 1.00 26.23  ? 232 LEU R O     1 
ATOM   1680 C CB    . LEU A 1 257 ? 117.283 133.037 137.299 1.00 26.23  ? 232 LEU R CB    1 
ATOM   1681 C CG    . LEU A 1 257 ? 118.672 133.521 137.727 1.00 26.23  ? 232 LEU R CG    1 
ATOM   1682 C CD1   . LEU A 1 257 ? 118.602 134.968 138.185 1.00 26.23  ? 232 LEU R CD1   1 
ATOM   1683 C CD2   . LEU A 1 257 ? 119.256 132.645 138.826 1.00 26.23  ? 232 LEU R CD2   1 
ATOM   1684 N N     . LEU A 1 258 ? 114.982 131.430 135.814 1.00 26.99  ? 233 LEU R N     1 
ATOM   1685 C CA    . LEU A 1 258 ? 113.585 131.039 135.678 1.00 26.99  ? 233 LEU R CA    1 
ATOM   1686 C C     . LEU A 1 258 ? 113.446 129.533 135.839 1.00 26.99  ? 233 LEU R C     1 
ATOM   1687 O O     . LEU A 1 258 ? 112.600 129.056 136.603 1.00 26.99  ? 233 LEU R O     1 
ATOM   1688 C CB    . LEU A 1 258 ? 113.035 131.481 134.322 1.00 26.99  ? 233 LEU R CB    1 
ATOM   1689 C CG    . LEU A 1 258 ? 111.535 131.275 134.104 1.00 26.99  ? 233 LEU R CG    1 
ATOM   1690 C CD1   . LEU A 1 258 ? 110.721 132.130 135.063 1.00 26.99  ? 233 LEU R CD1   1 
ATOM   1691 C CD2   . LEU A 1 258 ? 111.165 131.580 132.662 1.00 26.99  ? 233 LEU R CD2   1 
ATOM   1692 N N     . VAL A 1 259 ? 114.286 128.780 135.132 1.00 26.35  ? 234 VAL R N     1 
ATOM   1693 C CA    . VAL A 1 259 ? 114.252 127.322 135.184 1.00 26.35  ? 234 VAL R CA    1 
ATOM   1694 C C     . VAL A 1 259 ? 114.442 126.842 136.618 1.00 26.35  ? 234 VAL R C     1 
ATOM   1695 O O     . VAL A 1 259 ? 113.607 126.100 137.163 1.00 26.35  ? 234 VAL R O     1 
ATOM   1696 C CB    . VAL A 1 259 ? 115.333 126.728 134.261 1.00 26.35  ? 234 VAL R CB    1 
ATOM   1697 C CG1   . VAL A 1 259 ? 115.613 125.279 134.617 1.00 26.35  ? 234 VAL R CG1   1 
ATOM   1698 C CG2   . VAL A 1 259 ? 114.912 126.850 132.809 1.00 26.35  ? 234 VAL R CG2   1 
ATOM   1699 N N     . LEU A 1 260 ? 115.554 127.256 137.231 1.00 24.29  ? 235 LEU R N     1 
ATOM   1700 C CA    . LEU A 1 260 ? 115.895 126.772 138.564 1.00 24.29  ? 235 LEU R CA    1 
ATOM   1701 C C     . LEU A 1 260 ? 114.827 127.161 139.577 1.00 24.29  ? 235 LEU R C     1 
ATOM   1702 O O     . LEU A 1 260 ? 114.427 126.351 140.423 1.00 24.29  ? 235 LEU R O     1 
ATOM   1703 C CB    . LEU A 1 260 ? 117.257 127.330 138.981 1.00 24.29  ? 235 LEU R CB    1 
ATOM   1704 C CG    . LEU A 1 260 ? 118.472 126.427 138.755 1.00 24.29  ? 235 LEU R CG    1 
ATOM   1705 C CD1   . LEU A 1 260 ? 119.752 127.197 139.026 1.00 24.29  ? 235 LEU R CD1   1 
ATOM   1706 C CD2   . LEU A 1 260 ? 118.410 125.185 139.627 1.00 24.29  ? 235 LEU R CD2   1 
ATOM   1707 N N     . PHE A 1 261 ? 114.354 128.407 139.505 1.00 27.22  ? 236 PHE R N     1 
ATOM   1708 C CA    . PHE A 1 261 ? 113.359 128.889 140.452 1.00 27.22  ? 236 PHE R CA    1 
ATOM   1709 C C     . PHE A 1 261 ? 112.056 128.120 140.313 1.00 27.22  ? 236 PHE R C     1 
ATOM   1710 O O     . PHE A 1 261 ? 111.453 127.731 141.314 1.00 27.22  ? 236 PHE R O     1 
ATOM   1711 C CB    . PHE A 1 261 ? 113.127 130.386 140.245 1.00 27.22  ? 236 PHE R CB    1 
ATOM   1712 C CG    . PHE A 1 261 ? 112.057 130.962 141.126 1.00 27.22  ? 236 PHE R CG    1 
ATOM   1713 C CD1   . PHE A 1 261 ? 112.353 131.385 142.410 1.00 27.22  ? 236 PHE R CD1   1 
ATOM   1714 C CD2   . PHE A 1 261 ? 110.756 131.083 140.669 1.00 27.22  ? 236 PHE R CD2   1 
ATOM   1715 C CE1   . PHE A 1 261 ? 111.371 131.914 143.223 1.00 27.22  ? 236 PHE R CE1   1 
ATOM   1716 C CE2   . PHE A 1 261 ? 109.770 131.612 141.477 1.00 27.22  ? 236 PHE R CE2   1 
ATOM   1717 C CZ    . PHE A 1 261 ? 110.079 132.028 142.756 1.00 27.22  ? 236 PHE R CZ    1 
ATOM   1718 N N     . LEU A 1 262 ? 111.600 127.886 139.082 1.00 27.51  ? 237 LEU R N     1 
ATOM   1719 C CA    . LEU A 1 262 ? 110.369 127.128 138.901 1.00 27.51  ? 237 LEU R CA    1 
ATOM   1720 C C     . LEU A 1 262 ? 110.508 125.733 139.492 1.00 27.51  ? 237 LEU R C     1 
ATOM   1721 O O     . LEU A 1 262 ? 109.666 125.288 140.283 1.00 27.51  ? 237 LEU R O     1 
ATOM   1722 C CB    . LEU A 1 262 ? 110.007 127.053 137.417 1.00 27.51  ? 237 LEU R CB    1 
ATOM   1723 C CG    . LEU A 1 262 ? 109.467 128.336 136.786 1.00 27.51  ? 237 LEU R CG    1 
ATOM   1724 C CD1   . LEU A 1 262 ? 109.192 128.113 135.314 1.00 27.51  ? 237 LEU R CD1   1 
ATOM   1725 C CD2   . LEU A 1 262 ? 108.211 128.812 137.496 1.00 27.51  ? 237 LEU R CD2   1 
ATOM   1726 N N     . PHE A 1 263 ? 111.588 125.033 139.137 1.00 25.43  ? 238 PHE R N     1 
ATOM   1727 C CA    . PHE A 1 263 ? 111.751 123.666 139.622 1.00 25.43  ? 238 PHE R CA    1 
ATOM   1728 C C     . PHE A 1 263 ? 111.781 123.625 141.146 1.00 25.43  ? 238 PHE R C     1 
ATOM   1729 O O     . PHE A 1 263 ? 111.052 122.846 141.777 1.00 25.43  ? 238 PHE R O     1 
ATOM   1730 C CB    . PHE A 1 263 ? 113.026 123.050 139.045 1.00 25.43  ? 238 PHE R CB    1 
ATOM   1731 C CG    . PHE A 1 263 ? 113.220 121.607 139.413 1.00 25.43  ? 238 PHE R CG    1 
ATOM   1732 C CD1   . PHE A 1 263 ? 112.591 120.607 138.696 1.00 25.43  ? 238 PHE R CD1   1 
ATOM   1733 C CD2   . PHE A 1 263 ? 114.025 121.251 140.479 1.00 25.43  ? 238 PHE R CD2   1 
ATOM   1734 C CE1   . PHE A 1 263 ? 112.767 119.280 139.031 1.00 25.43  ? 238 PHE R CE1   1 
ATOM   1735 C CE2   . PHE A 1 263 ? 114.204 119.925 140.819 1.00 25.43  ? 238 PHE R CE2   1 
ATOM   1736 C CZ    . PHE A 1 263 ? 113.574 118.939 140.095 1.00 25.43  ? 238 PHE R CZ    1 
ATOM   1737 N N     . ALA A 1 264 ? 112.618 124.466 141.759 1.00 26.84  ? 239 ALA R N     1 
ATOM   1738 C CA    . ALA A 1 264 ? 112.740 124.453 143.213 1.00 26.84  ? 239 ALA R CA    1 
ATOM   1739 C C     . ALA A 1 264 ? 111.429 124.850 143.877 1.00 26.84  ? 239 ALA R C     1 
ATOM   1740 O O     . ALA A 1 264 ? 110.941 124.159 144.777 1.00 26.84  ? 239 ALA R O     1 
ATOM   1741 C CB    . ALA A 1 264 ? 113.869 125.386 143.650 1.00 26.84  ? 239 ALA R CB    1 
ATOM   1742 N N     . LEU A 1 265 ? 110.837 125.963 143.442 1.00 26.53  ? 240 LEU R N     1 
ATOM   1743 C CA    . LEU A 1 265 ? 109.610 126.443 144.060 1.00 26.53  ? 240 LEU R CA    1 
ATOM   1744 C C     . LEU A 1 265 ? 108.495 125.418 143.964 1.00 26.53  ? 240 LEU R C     1 
ATOM   1745 O O     . LEU A 1 265 ? 107.641 125.353 144.854 1.00 26.53  ? 240 LEU R O     1 
ATOM   1746 C CB    . LEU A 1 265 ? 109.176 127.752 143.400 1.00 26.53  ? 240 LEU R CB    1 
ATOM   1747 C CG    . LEU A 1 265 ? 107.920 128.424 143.962 1.00 26.53  ? 240 LEU R CG    1 
ATOM   1748 C CD1   . LEU A 1 265 ? 108.278 129.329 145.129 1.00 26.53  ? 240 LEU R CD1   1 
ATOM   1749 C CD2   . LEU A 1 265 ? 107.195 129.200 142.873 1.00 26.53  ? 240 LEU R CD2   1 
ATOM   1750 N N     . CYS A 1 266 ? 108.468 124.619 142.899 1.00 28.13  ? 241 CYS R N     1 
ATOM   1751 C CA    . CYS A 1 266 ? 107.368 123.685 142.718 1.00 28.13  ? 241 CYS R CA    1 
ATOM   1752 C C     . CYS A 1 266 ? 107.653 122.285 143.244 1.00 28.13  ? 241 CYS R C     1 
ATOM   1753 O O     . CYS A 1 266 ? 106.722 121.476 143.314 1.00 28.13  ? 241 CYS R O     1 
ATOM   1754 C CB    . CYS A 1 266 ? 107.001 123.591 141.241 1.00 28.13  ? 241 CYS R CB    1 
ATOM   1755 S SG    . CYS A 1 266 ? 106.002 124.968 140.628 1.00 28.13  ? 241 CYS R SG    1 
ATOM   1756 N N     . TRP A 1 267 ? 108.893 121.967 143.608 1.00 26.93  ? 242 TRP R N     1 
ATOM   1757 C CA    . TRP A 1 267 ? 109.168 120.641 144.155 1.00 26.93  ? 242 TRP R CA    1 
ATOM   1758 C C     . TRP A 1 267 ? 109.601 120.647 145.612 1.00 26.93  ? 242 TRP R C     1 
ATOM   1759 O O     . TRP A 1 267 ? 109.521 119.607 146.270 1.00 26.93  ? 242 TRP R O     1 
ATOM   1760 C CB    . TRP A 1 267 ? 110.235 119.931 143.307 1.00 26.93  ? 242 TRP R CB    1 
ATOM   1761 C CG    . TRP A 1 267 ? 109.653 119.252 142.101 1.00 26.93  ? 242 TRP R CG    1 
ATOM   1762 C CD1   . TRP A 1 267 ? 109.939 119.514 140.795 1.00 26.93  ? 242 TRP R CD1   1 
ATOM   1763 C CD2   . TRP A 1 267 ? 108.672 118.207 142.096 1.00 26.93  ? 242 TRP R CD2   1 
ATOM   1764 N NE1   . TRP A 1 267 ? 109.201 118.694 139.975 1.00 26.93  ? 242 TRP R NE1   1 
ATOM   1765 C CE2   . TRP A 1 267 ? 108.416 117.883 140.751 1.00 26.93  ? 242 TRP R CE2   1 
ATOM   1766 C CE3   . TRP A 1 267 ? 107.988 117.514 143.099 1.00 26.93  ? 242 TRP R CE3   1 
ATOM   1767 C CZ2   . TRP A 1 267 ? 107.506 116.896 140.383 1.00 26.93  ? 242 TRP R CZ2   1 
ATOM   1768 C CZ3   . TRP A 1 267 ? 107.087 116.536 142.731 1.00 26.93  ? 242 TRP R CZ3   1 
ATOM   1769 C CH2   . TRP A 1 267 ? 106.854 116.236 141.386 1.00 26.93  ? 242 TRP R CH2   1 
ATOM   1770 N N     . LEU A 1 268 ? 110.053 121.780 146.147 1.00 30.22  ? 243 LEU R N     1 
ATOM   1771 C CA    . LEU A 1 268 ? 110.486 121.840 147.538 1.00 30.22  ? 243 LEU R CA    1 
ATOM   1772 C C     . LEU A 1 268 ? 109.312 121.927 148.511 1.00 30.22  ? 243 LEU R C     1 
ATOM   1773 O O     . LEU A 1 268 ? 109.376 121.334 149.594 1.00 30.22  ? 243 LEU R O     1 
ATOM   1774 C CB    . LEU A 1 268 ? 111.424 123.030 147.748 1.00 30.22  ? 243 LEU R CB    1 
ATOM   1775 C CG    . LEU A 1 268 ? 112.924 122.727 147.663 1.00 30.22  ? 243 LEU R CG    1 
ATOM   1776 C CD1   . LEU A 1 268 ? 113.731 124.011 147.742 1.00 30.22  ? 243 LEU R CD1   1 
ATOM   1777 C CD2   . LEU A 1 268 ? 113.354 121.763 148.758 1.00 30.22  ? 243 LEU R CD2   1 
ATOM   1778 N N     . PRO A 1 269 ? 108.244 122.678 148.198 1.00 30.99  ? 244 PRO R N     1 
ATOM   1779 C CA    . PRO A 1 269 ? 107.124 122.778 149.146 1.00 30.99  ? 244 PRO R CA    1 
ATOM   1780 C C     . PRO A 1 269 ? 106.552 121.433 149.570 1.00 30.99  ? 244 PRO R C     1 
ATOM   1781 O O     . PRO A 1 269 ? 106.482 121.140 150.767 1.00 30.99  ? 244 PRO R O     1 
ATOM   1782 C CB    . PRO A 1 269 ? 106.083 123.600 148.377 1.00 30.99  ? 244 PRO R CB    1 
ATOM   1783 C CG    . PRO A 1 269 ? 106.852 124.393 147.407 1.00 30.99  ? 244 PRO R CG    1 
ATOM   1784 C CD    . PRO A 1 269 ? 108.151 123.688 147.130 1.00 30.99  ? 244 PRO R CD    1 
ATOM   1785 N N     . LEU A 1 270 ? 106.127 120.613 148.605 1.00 31.95  ? 245 LEU R N     1 
ATOM   1786 C CA    . LEU A 1 270 ? 105.536 119.324 148.948 1.00 31.95  ? 245 LEU R CA    1 
ATOM   1787 C C     . LEU A 1 270 ? 106.551 118.404 149.611 1.00 31.95  ? 245 LEU R C     1 
ATOM   1788 O O     . LEU A 1 270 ? 106.193 117.610 150.489 1.00 31.95  ? 245 LEU R O     1 
ATOM   1789 C CB    . LEU A 1 270 ? 104.956 118.664 147.695 1.00 31.95  ? 245 LEU R CB    1 
ATOM   1790 C CG    . LEU A 1 270 ? 104.295 117.298 147.893 1.00 31.95  ? 245 LEU R CG    1 
ATOM   1791 C CD1   . LEU A 1 270 ? 103.086 117.409 148.806 1.00 31.95  ? 245 LEU R CD1   1 
ATOM   1792 C CD2   . LEU A 1 270 ? 103.896 116.707 146.555 1.00 31.95  ? 245 LEU R CD2   1 
ATOM   1793 N N     . SER A 1 271 ? 107.818 118.492 149.207 1.00 32.17  ? 246 SER R N     1 
ATOM   1794 C CA    . SER A 1 271 ? 108.850 117.680 149.842 1.00 32.17  ? 246 SER R CA    1 
ATOM   1795 C C     . SER A 1 271 ? 109.006 118.038 151.314 1.00 32.17  ? 246 SER R C     1 
ATOM   1796 O O     . SER A 1 271 ? 109.114 117.150 152.167 1.00 32.17  ? 246 SER R O     1 
ATOM   1797 C CB    . SER A 1 271 ? 110.175 117.859 149.109 1.00 32.17  ? 246 SER R CB    1 
ATOM   1798 O OG    . SER A 1 271 ? 110.106 117.325 147.799 1.00 32.17  ? 246 SER R OG    1 
ATOM   1799 N N     . ILE A 1 272 ? 109.018 119.332 151.633 1.00 33.65  ? 247 ILE R N     1 
ATOM   1800 C CA    . ILE A 1 272 ? 109.113 119.748 153.028 1.00 33.65  ? 247 ILE R CA    1 
ATOM   1801 C C     . ILE A 1 272 ? 107.841 119.376 153.778 1.00 33.65  ? 247 ILE R C     1 
ATOM   1802 O O     . ILE A 1 272 ? 107.878 119.045 154.968 1.00 33.65  ? 247 ILE R O     1 
ATOM   1803 C CB    . ILE A 1 272 ? 109.411 121.256 153.115 1.00 33.65  ? 247 ILE R CB    1 
ATOM   1804 C CG1   . ILE A 1 272 ? 110.805 121.542 152.546 1.00 33.65  ? 247 ILE R CG1   1 
ATOM   1805 C CG2   . ILE A 1 272 ? 109.304 121.736 154.560 1.00 33.65  ? 247 ILE R CG2   1 
ATOM   1806 C CD1   . ILE A 1 272 ? 111.189 123.008 152.538 1.00 33.65  ? 247 ILE R CD1   1 
ATOM   1807 N N     . ILE A 1 273 ? 106.693 119.431 153.098 1.00 35.10  ? 248 ILE R N     1 
ATOM   1808 C CA    . ILE A 1 273 ? 105.440 118.998 153.713 1.00 35.10  ? 248 ILE R CA    1 
ATOM   1809 C C     . ILE A 1 273 ? 105.556 117.544 154.149 1.00 35.10  ? 248 ILE R C     1 
ATOM   1810 O O     . ILE A 1 273 ? 105.213 117.179 155.280 1.00 35.10  ? 248 ILE R O     1 
ATOM   1811 C CB    . ILE A 1 273 ? 104.267 119.196 152.737 1.00 35.10  ? 248 ILE R CB    1 
ATOM   1812 C CG1   . ILE A 1 273 ? 103.839 120.664 152.715 1.00 35.10  ? 248 ILE R CG1   1 
ATOM   1813 C CG2   . ILE A 1 273 ? 103.094 118.302 153.124 1.00 35.10  ? 248 ILE R CG2   1 
ATOM   1814 C CD1   . ILE A 1 273 ? 102.891 121.006 151.584 1.00 35.10  ? 248 ILE R CD1   1 
ATOM   1815 N N     . ASN A 1 274 ? 106.048 116.692 153.247 1.00 35.08  ? 249 ASN R N     1 
ATOM   1816 C CA    . ASN A 1 274 ? 106.240 115.283 153.581 1.00 35.08  ? 249 ASN R CA    1 
ATOM   1817 C C     . ASN A 1 274 ? 107.265 115.116 154.696 1.00 35.08  ? 249 ASN R C     1 
ATOM   1818 O O     . ASN A 1 274 ? 107.091 114.282 155.592 1.00 35.08  ? 249 ASN R O     1 
ATOM   1819 C CB    . ASN A 1 274 ? 106.675 114.502 152.342 1.00 35.08  ? 249 ASN R CB    1 
ATOM   1820 C CG    . ASN A 1 274 ? 105.541 114.277 151.366 1.00 35.08  ? 249 ASN R CG    1 
ATOM   1821 O OD1   . ASN A 1 274 ? 104.429 113.924 151.758 1.00 35.08  ? 249 ASN R OD1   1 
ATOM   1822 N ND2   . ASN A 1 274 ? 105.818 114.480 150.085 1.00 35.08  ? 249 ASN R ND2   1 
ATOM   1823 N N     . CYS A 1 275 ? 108.347 115.895 154.653 1.00 39.62  ? 250 CYS R N     1 
ATOM   1824 C CA    . CYS A 1 275 ? 109.380 115.787 155.678 1.00 39.62  ? 250 CYS R CA    1 
ATOM   1825 C C     . CYS A 1 275 ? 108.814 116.107 157.056 1.00 39.62  ? 250 CYS R C     1 
ATOM   1826 O O     . CYS A 1 275 ? 109.124 115.430 158.042 1.00 39.62  ? 250 CYS R O     1 
ATOM   1827 C CB    . CYS A 1 275 ? 110.543 116.720 155.341 1.00 39.62  ? 250 CYS R CB    1 
ATOM   1828 S SG    . CYS A 1 275 ? 112.106 116.284 156.137 1.00 39.62  ? 250 CYS R SG    1 
ATOM   1829 N N     . ILE A 1 276 ? 107.981 117.145 157.142 1.00 39.43  ? 251 ILE R N     1 
ATOM   1830 C CA    . ILE A 1 276 ? 107.362 117.494 158.416 1.00 39.43  ? 251 ILE R CA    1 
ATOM   1831 C C     . ILE A 1 276 ? 106.357 116.427 158.828 1.00 39.43  ? 251 ILE R C     1 
ATOM   1832 O O     . ILE A 1 276 ? 106.295 116.033 159.999 1.00 39.43  ? 251 ILE R O     1 
ATOM   1833 C CB    . ILE A 1 276 ? 106.714 118.888 158.329 1.00 39.43  ? 251 ILE R CB    1 
ATOM   1834 C CG1   . ILE A 1 276 ? 107.774 119.971 158.548 1.00 39.43  ? 251 ILE R CG1   1 
ATOM   1835 C CG2   . ILE A 1 276 ? 105.590 119.025 159.353 1.00 39.43  ? 251 ILE R CG2   1 
ATOM   1836 C CD1   . ILE A 1 276 ? 107.297 121.377 158.247 1.00 39.43  ? 251 ILE R CD1   1 
ATOM   1837 N N     . LEU A 1 277 ? 105.554 115.939 157.880 1.00 39.11  ? 252 LEU R N     1 
ATOM   1838 C CA    . LEU A 1 277 ? 104.596 114.885 158.182 1.00 39.11  ? 252 LEU R CA    1 
ATOM   1839 C C     . LEU A 1 277 ? 105.271 113.597 158.630 1.00 39.11  ? 252 LEU R C     1 
ATOM   1840 O O     . LEU A 1 277 ? 104.622 112.771 159.280 1.00 39.11  ? 252 LEU R O     1 
ATOM   1841 C CB    . LEU A 1 277 ? 103.725 114.607 156.955 1.00 39.11  ? 252 LEU R CB    1 
ATOM   1842 C CG    . LEU A 1 277 ? 102.668 115.663 156.630 1.00 39.11  ? 252 LEU R CG    1 
ATOM   1843 C CD1   . LEU A 1 277 ? 102.135 115.464 155.221 1.00 39.11  ? 252 LEU R CD1   1 
ATOM   1844 C CD2   . LEU A 1 277 ? 101.533 115.624 157.640 1.00 39.11  ? 252 LEU R CD2   1 
ATOM   1845 N N     . TYR A 1 278 ? 106.547 113.406 158.300 1.00 40.98  ? 253 TYR R N     1 
ATOM   1846 C CA    . TYR A 1 278 ? 107.285 112.217 158.704 1.00 40.98  ? 253 TYR R CA    1 
ATOM   1847 C C     . TYR A 1 278 ? 107.914 112.345 160.082 1.00 40.98  ? 253 TYR R C     1 
ATOM   1848 O O     . TYR A 1 278 ? 108.110 111.328 160.757 1.00 40.98  ? 253 TYR R O     1 
ATOM   1849 C CB    . TYR A 1 278 ? 108.385 111.909 157.681 1.00 40.98  ? 253 TYR R CB    1 
ATOM   1850 C CG    . TYR A 1 278 ? 109.489 111.020 158.208 1.00 40.98  ? 253 TYR R CG    1 
ATOM   1851 C CD1   . TYR A 1 278 ? 109.333 109.642 158.256 1.00 40.98  ? 253 TYR R CD1   1 
ATOM   1852 C CD2   . TYR A 1 278 ? 110.689 111.559 158.650 1.00 40.98  ? 253 TYR R CD2   1 
ATOM   1853 C CE1   . TYR A 1 278 ? 110.338 108.826 158.735 1.00 40.98  ? 253 TYR R CE1   1 
ATOM   1854 C CE2   . TYR A 1 278 ? 111.701 110.751 159.131 1.00 40.98  ? 253 TYR R CE2   1 
ATOM   1855 C CZ    . TYR A 1 278 ? 111.520 109.385 159.170 1.00 40.98  ? 253 TYR R CZ    1 
ATOM   1856 O OH    . TYR A 1 278 ? 112.523 108.574 159.647 1.00 40.98  ? 253 TYR R OH    1 
ATOM   1857 N N     . PHE A 1 279 ? 108.225 113.564 160.520 1.00 44.46  ? 254 PHE R N     1 
ATOM   1858 C CA    . PHE A 1 279 ? 108.861 113.796 161.809 1.00 44.46  ? 254 PHE R CA    1 
ATOM   1859 C C     . PHE A 1 279 ? 107.850 114.039 162.926 1.00 44.46  ? 254 PHE R C     1 
ATOM   1860 O O     . PHE A 1 279 ? 108.169 114.731 163.900 1.00 44.46  ? 254 PHE R O     1 
ATOM   1861 C CB    . PHE A 1 279 ? 109.834 114.974 161.704 1.00 44.46  ? 254 PHE R CB    1 
ATOM   1862 C CG    . PHE A 1 279 ? 111.153 114.616 161.077 1.00 44.46  ? 254 PHE R CG    1 
ATOM   1863 C CD1   . PHE A 1 279 ? 111.995 113.694 161.677 1.00 44.46  ? 254 PHE R CD1   1 
ATOM   1864 C CD2   . PHE A 1 279 ? 111.549 115.198 159.884 1.00 44.46  ? 254 PHE R CD2   1 
ATOM   1865 C CE1   . PHE A 1 279 ? 113.206 113.361 161.102 1.00 44.46  ? 254 PHE R CE1   1 
ATOM   1866 C CE2   . PHE A 1 279 ? 112.760 114.869 159.304 1.00 44.46  ? 254 PHE R CE2   1 
ATOM   1867 C CZ    . PHE A 1 279 ? 113.589 113.949 159.914 1.00 44.46  ? 254 PHE R CZ    1 
ATOM   1868 N N     . ASP A 1 280 ? 106.642 113.490 162.803 1.00 48.73  ? 255 ASP R N     1 
ATOM   1869 C CA    . ASP A 1 280 ? 105.581 113.545 163.807 1.00 48.73  ? 255 ASP R CA    1 
ATOM   1870 C C     . ASP A 1 280 ? 104.881 114.896 163.840 1.00 48.73  ? 255 ASP R C     1 
ATOM   1871 O O     . ASP A 1 280 ? 104.099 115.151 164.769 1.00 48.73  ? 255 ASP R O     1 
ATOM   1872 C CB    . ASP A 1 280 ? 106.104 113.225 165.212 1.00 48.73  ? 255 ASP R CB    1 
ATOM   1873 C CG    . ASP A 1 280 ? 107.006 112.006 165.236 1.00 48.73  ? 255 ASP R CG    1 
ATOM   1874 O OD1   . ASP A 1 280 ? 106.521 110.899 164.919 1.00 48.73  ? 255 ASP R OD1   1 
ATOM   1875 O OD2   . ASP A 1 280 ? 108.200 112.154 165.569 1.00 48.73  ? 255 ASP R OD2   1 
ATOM   1876 N N     . GLY A 1 281 ? 105.125 115.769 162.867 1.00 45.17  ? 256 GLY R N     1 
ATOM   1877 C CA    . GLY A 1 281 ? 104.471 117.058 162.818 1.00 45.17  ? 256 GLY R CA    1 
ATOM   1878 C C     . GLY A 1 281 ? 103.081 116.967 162.217 1.00 45.17  ? 256 GLY R C     1 
ATOM   1879 O O     . GLY A 1 281 ? 102.555 115.891 161.926 1.00 45.17  ? 256 GLY R O     1 
ATOM   1880 N N     . GLN A 1 282 ? 102.476 118.138 162.033 1.00 46.38  ? 257 GLN R N     1 
ATOM   1881 C CA    . GLN A 1 282 ? 101.156 118.255 161.434 1.00 46.38  ? 257 GLN R CA    1 
ATOM   1882 C C     . GLN A 1 282 ? 101.182 119.342 160.370 1.00 46.38  ? 257 GLN R C     1 
ATOM   1883 O O     . GLN A 1 282 ? 101.982 120.279 160.427 1.00 46.38  ? 257 GLN R O     1 
ATOM   1884 C CB    . GLN A 1 282 ? 100.082 118.577 162.484 1.00 46.38  ? 257 GLN R CB    1 
ATOM   1885 C CG    . GLN A 1 282 ? 99.835  117.459 163.486 1.00 46.38  ? 257 GLN R CG    1 
ATOM   1886 C CD    . GLN A 1 282 ? 100.842 117.453 164.620 1.00 46.38  ? 257 GLN R CD    1 
ATOM   1887 O OE1   . GLN A 1 282 ? 101.533 118.443 164.859 1.00 46.38  ? 257 GLN R OE1   1 
ATOM   1888 N NE2   . GLN A 1 282 ? 100.929 116.332 165.326 1.00 46.38  ? 257 GLN R NE2   1 
ATOM   1889 N N     . VAL A 1 283 ? 100.294 119.202 159.391 1.00 41.15  ? 258 VAL R N     1 
ATOM   1890 C CA    . VAL A 1 283 ? 100.201 120.154 158.287 1.00 41.15  ? 258 VAL R CA    1 
ATOM   1891 C C     . VAL A 1 283 ? 98.734  120.324 157.908 1.00 41.15  ? 258 VAL R C     1 
ATOM   1892 O O     . VAL A 1 283 ? 98.026  119.321 157.736 1.00 41.15  ? 258 VAL R O     1 
ATOM   1893 C CB    . VAL A 1 283 ? 101.032 119.690 157.080 1.00 41.15  ? 258 VAL R CB    1 
ATOM   1894 C CG1   . VAL A 1 283 ? 100.795 120.604 155.886 1.00 41.15  ? 258 VAL R CG1   1 
ATOM   1895 C CG2   . VAL A 1 283 ? 102.510 119.642 157.436 1.00 41.15  ? 258 VAL R CG2   1 
ATOM   1896 N N     . PRO A 1 284 ? 98.230  121.551 157.774 1.00 42.15  ? 259 PRO R N     1 
ATOM   1897 C CA    . PRO A 1 284 ? 96.852  121.720 157.300 1.00 42.15  ? 259 PRO R CA    1 
ATOM   1898 C C     . PRO A 1 284 ? 96.648  121.059 155.946 1.00 42.15  ? 259 PRO R C     1 
ATOM   1899 O O     . PRO A 1 284 ? 97.532  121.061 155.087 1.00 42.15  ? 259 PRO R O     1 
ATOM   1900 C CB    . PRO A 1 284 ? 96.682  123.241 157.206 1.00 42.15  ? 259 PRO R CB    1 
ATOM   1901 C CG    . PRO A 1 284 ? 97.804  123.844 157.974 1.00 42.15  ? 259 PRO R CG    1 
ATOM   1902 C CD    . PRO A 1 284 ? 98.770  122.779 158.380 1.00 42.15  ? 259 PRO R CD    1 
ATOM   1903 N N     . GLN A 1 285 ? 95.458  120.484 155.764 1.00 43.05  ? 260 GLN R N     1 
ATOM   1904 C CA    . GLN A 1 285 ? 95.147  119.805 154.510 1.00 43.05  ? 260 GLN R CA    1 
ATOM   1905 C C     . GLN A 1 285 ? 95.259  120.751 153.320 1.00 43.05  ? 260 GLN R C     1 
ATOM   1906 O O     . GLN A 1 285 ? 95.669  120.335 152.226 1.00 43.05  ? 260 GLN R O     1 
ATOM   1907 C CB    . GLN A 1 285 ? 93.743  119.204 154.587 1.00 43.05  ? 260 GLN R CB    1 
ATOM   1908 C CG    . GLN A 1 285 ? 93.318  118.437 153.351 1.00 43.05  ? 260 GLN R CG    1 
ATOM   1909 C CD    . GLN A 1 285 ? 94.359  117.436 152.898 1.00 43.05  ? 260 GLN R CD    1 
ATOM   1910 O OE1   . GLN A 1 285 ? 94.922  117.557 151.811 1.00 43.05  ? 260 GLN R OE1   1 
ATOM   1911 N NE2   . GLN A 1 285 ? 94.622  116.438 153.734 1.00 43.05  ? 260 GLN R NE2   1 
ATOM   1912 N N     . THR A 1 286 ? 94.904  122.023 153.512 1.00 42.13  ? 261 THR R N     1 
ATOM   1913 C CA    . THR A 1 286 ? 95.018  122.997 152.433 1.00 42.13  ? 261 THR R CA    1 
ATOM   1914 C C     . THR A 1 286 ? 96.462  123.124 151.967 1.00 42.13  ? 261 THR R C     1 
ATOM   1915 O O     . THR A 1 286 ? 96.727  123.276 150.770 1.00 42.13  ? 261 THR R O     1 
ATOM   1916 C CB    . THR A 1 286 ? 94.479  124.353 152.891 1.00 42.13  ? 261 THR R CB    1 
ATOM   1917 O OG1   . THR A 1 286 ? 93.112  124.214 153.299 1.00 42.13  ? 261 THR R OG1   1 
ATOM   1918 C CG2   . THR A 1 286 ? 94.568  125.374 151.765 1.00 42.13  ? 261 THR R CG2   1 
ATOM   1919 N N     . VAL A 1 287 ? 97.413  123.061 152.901 1.00 40.10  ? 262 VAL R N     1 
ATOM   1920 C CA    . VAL A 1 287 ? 98.825  123.129 152.534 1.00 40.10  ? 262 VAL R CA    1 
ATOM   1921 C C     . VAL A 1 287 ? 99.212  121.928 151.677 1.00 40.10  ? 262 VAL R C     1 
ATOM   1922 O O     . VAL A 1 287 ? 99.994  122.047 150.724 1.00 40.10  ? 262 VAL R O     1 
ATOM   1923 C CB    . VAL A 1 287 ? 99.693  123.229 153.804 1.00 40.10  ? 262 VAL R CB    1 
ATOM   1924 C CG1   . VAL A 1 287 ? 101.147 122.929 153.492 1.00 40.10  ? 262 VAL R CG1   1 
ATOM   1925 C CG2   . VAL A 1 287 ? 99.552  124.607 154.430 1.00 40.10  ? 262 VAL R CG2   1 
ATOM   1926 N N     . LEU A 1 288 ? 98.679  120.752 152.006 1.00 38.29  ? 263 LEU R N     1 
ATOM   1927 C CA    . LEU A 1 288 ? 98.945  119.546 151.232 1.00 38.29  ? 263 LEU R CA    1 
ATOM   1928 C C     . LEU A 1 288 ? 98.420  119.705 149.811 1.00 38.29  ? 263 LEU R C     1 
ATOM   1929 O O     . LEU A 1 288 ? 99.113  119.380 148.834 1.00 38.29  ? 263 LEU R O     1 
ATOM   1930 C CB    . LEU A 1 288 ? 98.303  118.334 151.909 1.00 38.29  ? 263 LEU R CB    1 
ATOM   1931 C CG    . LEU A 1 288 ? 98.613  116.961 151.312 1.00 38.29  ? 263 LEU R CG    1 
ATOM   1932 C CD1   . LEU A 1 288 ? 100.093 116.645 151.432 1.00 38.29  ? 263 LEU R CD1   1 
ATOM   1933 C CD2   . LEU A 1 288 ? 97.777  115.887 151.991 1.00 38.29  ? 263 LEU R CD2   1 
ATOM   1934 N N     . TYR A 1 289 ? 97.192  120.208 149.689 1.00 41.04  ? 264 TYR R N     1 
ATOM   1935 C CA    . TYR A 1 289 ? 96.627  120.455 148.370 1.00 41.04  ? 264 TYR R CA    1 
ATOM   1936 C C     . TYR A 1 289 ? 97.505  121.446 147.618 1.00 41.04  ? 264 TYR R C     1 
ATOM   1937 O O     . TYR A 1 289 ? 97.746  121.285 146.419 1.00 41.04  ? 264 TYR R O     1 
ATOM   1938 C CB    . TYR A 1 289 ? 95.194  120.987 148.468 1.00 41.04  ? 264 TYR R CB    1 
ATOM   1939 C CG    . TYR A 1 289 ? 94.181  120.005 149.019 1.00 41.04  ? 264 TYR R CG    1 
ATOM   1940 C CD1   . TYR A 1 289 ? 94.305  118.640 148.795 1.00 41.04  ? 264 TYR R CD1   1 
ATOM   1941 C CD2   . TYR A 1 289 ? 93.078  120.450 149.736 1.00 41.04  ? 264 TYR R CD2   1 
ATOM   1942 C CE1   . TYR A 1 289 ? 93.373  117.747 149.288 1.00 41.04  ? 264 TYR R CE1   1 
ATOM   1943 C CE2   . TYR A 1 289 ? 92.140  119.566 150.229 1.00 41.04  ? 264 TYR R CE2   1 
ATOM   1944 C CZ    . TYR A 1 289 ? 92.293  118.215 150.003 1.00 41.04  ? 264 TYR R CZ    1 
ATOM   1945 O OH    . TYR A 1 289 ? 91.362  117.331 150.495 1.00 41.04  ? 264 TYR R OH    1 
ATOM   1946 N N     . LEU A 1 290 ? 97.982  122.473 148.317 1.00 38.07  ? 265 LEU R N     1 
ATOM   1947 C CA    . LEU A 1 290 ? 98.837  123.487 147.716 1.00 38.07  ? 265 LEU R CA    1 
ATOM   1948 C C     . LEU A 1 290 ? 100.090 122.856 147.127 1.00 38.07  ? 265 LEU R C     1 
ATOM   1949 O O     . LEU A 1 290 ? 100.466 123.158 145.992 1.00 38.07  ? 265 LEU R O     1 
ATOM   1950 C CB    . LEU A 1 290 ? 99.217  124.544 148.754 1.00 38.07  ? 265 LEU R CB    1 
ATOM   1951 C CG    . LEU A 1 290 ? 99.776  125.857 148.203 1.00 38.07  ? 265 LEU R CG    1 
ATOM   1952 C CD1   . LEU A 1 290 ? 98.646  126.801 147.823 1.00 38.07  ? 265 LEU R CD1   1 
ATOM   1953 C CD2   . LEU A 1 290 ? 100.707 126.506 149.216 1.00 38.07  ? 265 LEU R CD2   1 
ATOM   1954 N N     . GLY A 1 291 ? 100.745 121.988 147.893 1.00 34.94  ? 266 GLY R N     1 
ATOM   1955 C CA    . GLY A 1 291 ? 101.948 121.324 147.421 1.00 34.94  ? 266 GLY R CA    1 
ATOM   1956 C C     . GLY A 1 291 ? 101.706 120.455 146.201 1.00 34.94  ? 266 GLY R C     1 
ATOM   1957 O O     . GLY A 1 291 ? 102.465 120.497 145.217 1.00 34.94  ? 266 GLY R O     1 
ATOM   1958 N N     . ILE A 1 292 ? 100.639 119.653 146.259 1.00 34.88  ? 267 ILE R N     1 
ATOM   1959 C CA    . ILE A 1 292 ? 100.299 118.803 145.119 1.00 34.88  ? 267 ILE R CA    1 
ATOM   1960 C C     . ILE A 1 292 ? 100.070 119.659 143.879 1.00 34.88  ? 267 ILE R C     1 
ATOM   1961 O O     . ILE A 1 292 ? 100.567 119.355 142.783 1.00 34.88  ? 267 ILE R O     1 
ATOM   1962 C CB    . ILE A 1 292 ? 99.065  117.942 145.441 1.00 34.88  ? 267 ILE R CB    1 
ATOM   1963 C CG1   . ILE A 1 292 ? 99.384  116.953 146.564 1.00 34.88  ? 267 ILE R CG1   1 
ATOM   1964 C CG2   . ILE A 1 292 ? 98.599  117.207 144.193 1.00 34.88  ? 267 ILE R CG2   1 
ATOM   1965 C CD1   . ILE A 1 292 ? 98.161  116.285 147.153 1.00 34.88  ? 267 ILE R CD1   1 
ATOM   1966 N N     . LEU A 1 293 ? 99.312  120.744 144.038 1.00 37.93  ? 268 LEU R N     1 
ATOM   1967 C CA    . LEU A 1 293 ? 99.019  121.616 142.909 1.00 37.93  ? 268 LEU R CA    1 
ATOM   1968 C C     . LEU A 1 293 ? 100.281 122.284 142.386 1.00 37.93  ? 268 LEU R C     1 
ATOM   1969 O O     . LEU A 1 293 ? 100.426 122.479 141.178 1.00 37.93  ? 268 LEU R O     1 
ATOM   1970 C CB    . LEU A 1 293 ? 97.981  122.661 143.316 1.00 37.93  ? 268 LEU R CB    1 
ATOM   1971 C CG    . LEU A 1 293 ? 96.612  122.099 143.704 1.00 37.93  ? 268 LEU R CG    1 
ATOM   1972 C CD1   . LEU A 1 293 ? 95.728  123.197 144.271 1.00 37.93  ? 268 LEU R CD1   1 
ATOM   1973 C CD2   . LEU A 1 293 ? 95.951  121.425 142.513 1.00 37.93  ? 268 LEU R CD2   1 
ATOM   1974 N N     . LEU A 1 294 ? 101.209 122.645 143.274 1.00 33.10  ? 269 LEU R N     1 
ATOM   1975 C CA    . LEU A 1 294 ? 102.452 123.266 142.827 1.00 33.10  ? 269 LEU R CA    1 
ATOM   1976 C C     . LEU A 1 294 ? 103.260 122.309 141.959 1.00 33.10  ? 269 LEU R C     1 
ATOM   1977 O O     . LEU A 1 294 ? 103.780 122.692 140.902 1.00 33.10  ? 269 LEU R O     1 
ATOM   1978 C CB    . LEU A 1 294 ? 103.275 123.723 144.034 1.00 33.10  ? 269 LEU R CB    1 
ATOM   1979 C CG    . LEU A 1 294 ? 102.838 124.993 144.775 1.00 33.10  ? 269 LEU R CG    1 
ATOM   1980 C CD1   . LEU A 1 294 ? 103.975 125.512 145.638 1.00 33.10  ? 269 LEU R CD1   1 
ATOM   1981 C CD2   . LEU A 1 294 ? 102.359 126.083 143.825 1.00 33.10  ? 269 LEU R CD2   1 
ATOM   1982 N N     . SER A 1 295 ? 103.382 121.053 142.392 1.00 30.78  ? 270 SER R N     1 
ATOM   1983 C CA    . SER A 1 295 ? 104.108 120.080 141.576 1.00 30.78  ? 270 SER R CA    1 
ATOM   1984 C C     . SER A 1 295 ? 103.427 119.878 140.224 1.00 30.78  ? 270 SER R C     1 
ATOM   1985 O O     . SER A 1 295 ? 104.069 119.963 139.161 1.00 30.78  ? 270 SER R O     1 
ATOM   1986 C CB    . SER A 1 295 ? 104.220 118.754 142.326 1.00 30.78  ? 270 SER R CB    1 
ATOM   1987 O OG    . SER A 1 295 ? 104.612 118.964 143.671 1.00 30.78  ? 270 SER R OG    1 
ATOM   1988 N N     . HIS A 1 296 ? 102.118 119.633 140.239 1.00 34.07  ? 271 HIS R N     1 
ATOM   1989 C CA    . HIS A 1 296 ? 101.418 119.404 138.983 1.00 34.07  ? 271 HIS R CA    1 
ATOM   1990 C C     . HIS A 1 296 ? 101.327 120.674 138.145 1.00 34.07  ? 271 HIS R C     1 
ATOM   1991 O O     . HIS A 1 296 ? 100.970 120.601 136.965 1.00 34.07  ? 271 HIS R O     1 
ATOM   1992 C CB    . HIS A 1 296 ? 100.031 118.826 139.263 1.00 34.07  ? 271 HIS R CB    1 
ATOM   1993 C CG    . HIS A 1 296 ? 100.060 117.553 140.053 1.00 34.07  ? 271 HIS R CG    1 
ATOM   1994 N ND1   . HIS A 1 296 ? 99.033  116.635 140.023 1.00 34.07  ? 271 HIS R ND1   1 
ATOM   1995 C CD2   . HIS A 1 296 ? 100.996 117.042 140.888 1.00 34.07  ? 271 HIS R CD2   1 
ATOM   1996 C CE1   . HIS A 1 296 ? 99.334  115.616 140.809 1.00 34.07  ? 271 HIS R CE1   1 
ATOM   1997 N NE2   . HIS A 1 296 ? 100.519 115.839 141.346 1.00 34.07  ? 271 HIS R NE2   1 
ATOM   1998 N N     . ALA A 1 297 ? 101.647 121.831 138.731 1.00 34.14  ? 272 ALA R N     1 
ATOM   1999 C CA    . ALA A 1 297 ? 101.717 123.067 137.963 1.00 34.14  ? 272 ALA R CA    1 
ATOM   2000 C C     . ALA A 1 297 ? 103.078 123.222 137.305 1.00 34.14  ? 272 ALA R C     1 
ATOM   2001 O O     . ALA A 1 297 ? 103.179 123.764 136.201 1.00 34.14  ? 272 ALA R O     1 
ATOM   2002 C CB    . ALA A 1 297 ? 101.423 124.262 138.867 1.00 34.14  ? 272 ALA R CB    1 
ATOM   2003 N N     . ASN A 1 298 ? 104.141 122.777 137.976 1.00 30.11  ? 273 ASN R N     1 
ATOM   2004 C CA    . ASN A 1 298 ? 105.426 122.655 137.292 1.00 30.11  ? 273 ASN R CA    1 
ATOM   2005 C C     . ASN A 1 298 ? 105.285 121.761 136.073 1.00 30.11  ? 273 ASN R C     1 
ATOM   2006 O O     . ASN A 1 298 ? 105.885 122.012 135.017 1.00 30.11  ? 273 ASN R O     1 
ATOM   2007 C CB    . ASN A 1 298 ? 106.485 122.087 138.231 1.00 30.11  ? 273 ASN R CB    1 
ATOM   2008 C CG    . ASN A 1 298 ? 107.875 122.130 137.631 1.00 30.11  ? 273 ASN R CG    1 
ATOM   2009 O OD1   . ASN A 1 298 ? 108.059 122.561 136.493 1.00 30.11  ? 273 ASN R OD1   1 
ATOM   2010 N ND2   . ASN A 1 298 ? 108.863 121.668 138.388 1.00 30.11  ? 273 ASN R ND2   1 
ATOM   2011 N N     . SER A 1 299 ? 104.487 120.700 136.211 1.00 33.45  ? 274 SER R N     1 
ATOM   2012 C CA    . SER A 1 299 ? 104.245 119.804 135.086 1.00 33.45  ? 274 SER R CA    1 
ATOM   2013 C C     . SER A 1 299 ? 103.830 120.576 133.833 1.00 33.45  ? 274 SER R C     1 
ATOM   2014 O O     . SER A 1 299 ? 104.321 120.303 132.732 1.00 33.45  ? 274 SER R O     1 
ATOM   2015 C CB    . SER A 1 299 ? 103.175 118.774 135.457 1.00 33.45  ? 274 SER R CB    1 
ATOM   2016 O OG    . SER A 1 299 ? 102.867 117.949 134.348 1.00 33.45  ? 274 SER R OG    1 
ATOM   2017 N N     . MET A 1 300 ? 102.919 121.545 133.980 1.00 36.65  ? 275 MET R N     1 
ATOM   2018 C CA    . MET A 1 300 ? 102.471 122.333 132.834 1.00 36.65  ? 275 MET R CA    1 
ATOM   2019 C C     . MET A 1 300 ? 103.390 123.507 132.523 1.00 36.65  ? 275 MET R C     1 
ATOM   2020 O O     . MET A 1 300 ? 103.418 123.965 131.376 1.00 36.65  ? 275 MET R O     1 
ATOM   2021 C CB    . MET A 1 300 ? 101.056 122.877 133.064 1.00 36.65  ? 275 MET R CB    1 
ATOM   2022 C CG    . MET A 1 300 ? 100.945 123.882 134.197 1.00 36.65  ? 275 MET R CG    1 
ATOM   2023 S SD    . MET A 1 300 ? 99.259  124.460 134.464 1.00 36.65  ? 275 MET R SD    1 
ATOM   2024 C CE    . MET A 1 300 ? 99.502  125.580 135.841 1.00 36.65  ? 275 MET R CE    1 
ATOM   2025 N N     . MET A 1 301 ? 104.118 124.018 133.515 1.00 33.35  ? 276 MET R N     1 
ATOM   2026 C CA    . MET A 1 301 ? 104.972 125.178 133.296 1.00 33.35  ? 276 MET R CA    1 
ATOM   2027 C C     . MET A 1 301 ? 106.235 124.824 132.527 1.00 33.35  ? 276 MET R C     1 
ATOM   2028 O O     . MET A 1 301 ? 106.812 125.694 131.866 1.00 33.35  ? 276 MET R O     1 
ATOM   2029 C CB    . MET A 1 301 ? 105.347 125.816 134.635 1.00 33.35  ? 276 MET R CB    1 
ATOM   2030 C CG    . MET A 1 301 ? 104.220 126.590 135.303 1.00 33.35  ? 276 MET R CG    1 
ATOM   2031 S SD    . MET A 1 301 ? 103.669 128.016 134.347 1.00 33.35  ? 276 MET R SD    1 
ATOM   2032 C CE    . MET A 1 301 ? 105.098 129.088 134.478 1.00 33.35  ? 276 MET R CE    1 
ATOM   2033 N N     . ASN A 1 302 ? 106.682 123.572 132.605 1.00 30.51  ? 277 ASN R N     1 
ATOM   2034 C CA    . ASN A 1 302 ? 107.922 123.198 131.925 1.00 30.51  ? 277 ASN R CA    1 
ATOM   2035 C C     . ASN A 1 302 ? 107.922 123.575 130.449 1.00 30.51  ? 277 ASN R C     1 
ATOM   2036 O O     . ASN A 1 302 ? 108.922 124.148 129.981 1.00 30.51  ? 277 ASN R O     1 
ATOM   2037 C CB    . ASN A 1 302 ? 108.172 121.698 132.101 1.00 30.51  ? 277 ASN R CB    1 
ATOM   2038 C CG    . ASN A 1 302 ? 108.930 121.376 133.371 1.00 30.51  ? 277 ASN R CG    1 
ATOM   2039 O OD1   . ASN A 1 302 ? 109.506 122.257 134.008 1.00 30.51  ? 277 ASN R OD1   1 
ATOM   2040 N ND2   . ASN A 1 302 ? 108.933 120.103 133.747 1.00 30.51  ? 277 ASN R ND2   1 
ATOM   2041 N N     . PRO A 1 303 ? 106.879 123.292 129.666 1.00 32.93  ? 278 PRO R N     1 
ATOM   2042 C CA    . PRO A 1 303 ? 106.915 123.656 128.239 1.00 32.93  ? 278 PRO R CA    1 
ATOM   2043 C C     . PRO A 1 303 ? 107.184 125.126 127.969 1.00 32.93  ? 278 PRO R C     1 
ATOM   2044 O O     . PRO A 1 303 ? 107.897 125.446 127.009 1.00 32.93  ? 278 PRO R O     1 
ATOM   2045 C CB    . PRO A 1 303 ? 105.519 123.253 127.750 1.00 32.93  ? 278 PRO R CB    1 
ATOM   2046 C CG    . PRO A 1 303 ? 105.120 122.133 128.630 1.00 32.93  ? 278 PRO R CG    1 
ATOM   2047 C CD    . PRO A 1 303 ? 105.800 122.334 129.962 1.00 32.93  ? 278 PRO R CD    1 
ATOM   2048 N N     . ILE A 1 304 ? 106.639 126.034 128.776 1.00 32.08  ? 279 ILE R N     1 
ATOM   2049 C CA    . ILE A 1 304 ? 106.766 127.462 128.506 1.00 32.08  ? 279 ILE R CA    1 
ATOM   2050 C C     . ILE A 1 304 ? 108.173 127.990 128.771 1.00 32.08  ? 279 ILE R C     1 
ATOM   2051 O O     . ILE A 1 304 ? 108.507 129.087 128.298 1.00 32.08  ? 279 ILE R O     1 
ATOM   2052 C CB    . ILE A 1 304 ? 105.733 128.265 129.327 1.00 32.08  ? 279 ILE R CB    1 
ATOM   2053 C CG1   . ILE A 1 304 ? 104.310 127.936 128.864 1.00 32.08  ? 279 ILE R CG1   1 
ATOM   2054 C CG2   . ILE A 1 304 ? 105.987 129.764 129.210 1.00 32.08  ? 279 ILE R CG2   1 
ATOM   2055 C CD1   . ILE A 1 304 ? 103.659 126.803 129.627 1.00 32.08  ? 279 ILE R CD1   1 
ATOM   2056 N N     . VAL A 1 305 ? 109.013 127.241 129.486 1.00 28.98  ? 280 VAL R N     1 
ATOM   2057 C CA    . VAL A 1 305 ? 110.321 127.727 129.905 1.00 28.98  ? 280 VAL R CA    1 
ATOM   2058 C C     . VAL A 1 305 ? 111.459 127.012 129.183 1.00 28.98  ? 280 VAL R C     1 
ATOM   2059 O O     . VAL A 1 305 ? 112.602 127.477 129.227 1.00 28.98  ? 280 VAL R O     1 
ATOM   2060 C CB    . VAL A 1 305 ? 110.475 127.607 131.430 1.00 28.98  ? 280 VAL R CB    1 
ATOM   2061 C CG1   . VAL A 1 305 ? 111.887 127.969 131.869 1.00 28.98  ? 280 VAL R CG1   1 
ATOM   2062 C CG2   . VAL A 1 305 ? 109.447 128.486 132.128 1.00 28.98  ? 280 VAL R CG2   1 
ATOM   2063 N N     . TYR A 1 306 ? 111.175 125.897 128.510 1.00 26.53  ? 281 TYR R N     1 
ATOM   2064 C CA    . TYR A 1 306 ? 112.221 125.141 127.830 1.00 26.53  ? 281 TYR R CA    1 
ATOM   2065 C C     . TYR A 1 306 ? 112.043 125.162 126.318 1.00 26.53  ? 281 TYR R C     1 
ATOM   2066 O O     . TYR A 1 306 ? 112.948 125.574 125.587 1.00 26.53  ? 281 TYR R O     1 
ATOM   2067 C CB    . TYR A 1 306 ? 112.235 123.696 128.329 1.00 26.53  ? 281 TYR R CB    1 
ATOM   2068 C CG    . TYR A 1 306 ? 113.057 123.489 129.577 1.00 26.53  ? 281 TYR R CG    1 
ATOM   2069 C CD1   . TYR A 1 306 ? 114.442 123.455 129.518 1.00 26.53  ? 281 TYR R CD1   1 
ATOM   2070 C CD2   . TYR A 1 306 ? 112.450 123.324 130.812 1.00 26.53  ? 281 TYR R CD2   1 
ATOM   2071 C CE1   . TYR A 1 306 ? 115.199 123.263 130.655 1.00 26.53  ? 281 TYR R CE1   1 
ATOM   2072 C CE2   . TYR A 1 306 ? 113.199 123.133 131.953 1.00 26.53  ? 281 TYR R CE2   1 
ATOM   2073 C CZ    . TYR A 1 306 ? 114.572 123.102 131.869 1.00 26.53  ? 281 TYR R CZ    1 
ATOM   2074 O OH    . TYR A 1 306 ? 115.324 122.908 133.002 1.00 26.53  ? 281 TYR R OH    1 
ATOM   2075 N N     . ALA A 1 307 ? 110.879 124.721 125.838 1.00 34.60  ? 282 ALA R N     1 
ATOM   2076 C CA    . ALA A 1 307 ? 110.669 124.625 124.398 1.00 34.60  ? 282 ALA R CA    1 
ATOM   2077 C C     . ALA A 1 307 ? 110.434 125.991 123.770 1.00 34.60  ? 282 ALA R C     1 
ATOM   2078 O O     . ALA A 1 307 ? 110.743 126.192 122.590 1.00 34.60  ? 282 ALA R O     1 
ATOM   2079 C CB    . ALA A 1 307 ? 109.492 123.697 124.102 1.00 34.60  ? 282 ALA R CB    1 
ATOM   2080 N N     . TYR A 1 308 ? 109.895 126.937 124.533 1.00 38.96  ? 283 TYR R N     1 
ATOM   2081 C CA    . TYR A 1 308 ? 109.542 128.249 124.011 1.00 38.96  ? 283 TYR R CA    1 
ATOM   2082 C C     . TYR A 1 308 ? 110.727 129.203 123.937 1.00 38.96  ? 283 TYR R C     1 
ATOM   2083 O O     . TYR A 1 308 ? 110.588 130.293 123.375 1.00 38.96  ? 283 TYR R O     1 
ATOM   2084 C CB    . TYR A 1 308 ? 108.439 128.872 124.872 1.00 38.96  ? 283 TYR R CB    1 
ATOM   2085 C CG    . TYR A 1 308 ? 107.722 130.024 124.207 1.00 38.96  ? 283 TYR R CG    1 
ATOM   2086 C CD1   . TYR A 1 308 ? 106.717 129.798 123.278 1.00 38.96  ? 283 TYR R CD1   1 
ATOM   2087 C CD2   . TYR A 1 308 ? 108.047 131.338 124.514 1.00 38.96  ? 283 TYR R CD2   1 
ATOM   2088 C CE1   . TYR A 1 308 ? 106.059 130.849 122.669 1.00 38.96  ? 283 TYR R CE1   1 
ATOM   2089 C CE2   . TYR A 1 308 ? 107.395 132.394 123.911 1.00 38.96  ? 283 TYR R CE2   1 
ATOM   2090 C CZ    . TYR A 1 308 ? 106.402 132.144 122.989 1.00 38.96  ? 283 TYR R CZ    1 
ATOM   2091 O OH    . TYR A 1 308 ? 105.749 133.195 122.386 1.00 38.96  ? 283 TYR R OH    1 
ATOM   2092 N N     . LYS A 1 309 ? 111.884 128.826 124.479 1.00 34.77  ? 284 LYS R N     1 
ATOM   2093 C CA    . LYS A 1 309 ? 113.052 129.697 124.451 1.00 34.77  ? 284 LYS R CA    1 
ATOM   2094 C C     . LYS A 1 309 ? 113.918 129.498 123.216 1.00 34.77  ? 284 LYS R C     1 
ATOM   2095 O O     . LYS A 1 309 ? 114.875 130.256 123.021 1.00 34.77  ? 284 LYS R O     1 
ATOM   2096 C CB    . LYS A 1 309 ? 113.902 129.478 125.706 1.00 34.77  ? 284 LYS R CB    1 
ATOM   2097 C CG    . LYS A 1 309 ? 113.103 129.444 127.002 1.00 34.77  ? 284 LYS R CG    1 
ATOM   2098 C CD    . LYS A 1 309 ? 112.444 130.783 127.306 1.00 34.77  ? 284 LYS R CD    1 
ATOM   2099 C CE    . LYS A 1 309 ? 113.418 131.748 127.962 1.00 34.77  ? 284 LYS R CE    1 
ATOM   2100 N NZ    . LYS A 1 309 ? 113.817 131.301 129.324 1.00 34.77  ? 284 LYS R NZ    1 
ATOM   2101 N N     . ILE A 1 310 ? 113.613 128.508 122.383 1.00 38.66  ? 285 ILE R N     1 
ATOM   2102 C CA    . ILE A 1 310 ? 114.322 128.299 121.126 1.00 38.66  ? 285 ILE R CA    1 
ATOM   2103 C C     . ILE A 1 310 ? 113.606 129.094 120.041 1.00 38.66  ? 285 ILE R C     1 
ATOM   2104 O O     . ILE A 1 310 ? 112.397 128.937 119.841 1.00 38.66  ? 285 ILE R O     1 
ATOM   2105 C CB    . ILE A 1 310 ? 114.393 126.808 120.765 1.00 38.66  ? 285 ILE R CB    1 
ATOM   2106 C CG1   . ILE A 1 310 ? 115.219 126.051 121.805 1.00 38.66  ? 285 ILE R CG1   1 
ATOM   2107 C CG2   . ILE A 1 310 ? 114.992 126.622 119.377 1.00 38.66  ? 285 ILE R CG2   1 
ATOM   2108 C CD1   . ILE A 1 310 ? 114.397 125.443 122.915 1.00 38.66  ? 285 ILE R CD1   1 
ATOM   2109 N N     . LYS A 1 311 ? 114.354 129.947 119.338 1.00 44.65  ? 286 LYS R N     1 
ATOM   2110 C CA    . LYS A 1 311 ? 113.743 130.792 118.318 1.00 44.65  ? 286 LYS R CA    1 
ATOM   2111 C C     . LYS A 1 311 ? 113.083 129.953 117.232 1.00 44.65  ? 286 LYS R C     1 
ATOM   2112 O O     . LYS A 1 311 ? 112.027 130.325 116.707 1.00 44.65  ? 286 LYS R O     1 
ATOM   2113 C CB    . LYS A 1 311 ? 114.793 131.729 117.717 1.00 44.65  ? 286 LYS R CB    1 
ATOM   2114 C CG    . LYS A 1 311 ? 114.345 132.453 116.452 1.00 44.65  ? 286 LYS R CG    1 
ATOM   2115 C CD    . LYS A 1 311 ? 115.437 133.363 115.914 1.00 44.65  ? 286 LYS R CD    1 
ATOM   2116 C CE    . LYS A 1 311 ? 115.596 134.609 116.772 1.00 44.65  ? 286 LYS R CE    1 
ATOM   2117 N NZ    . LYS A 1 311 ? 116.302 135.700 116.045 1.00 44.65  ? 286 LYS R NZ    1 
ATOM   2118 N N     . LYS A 1 312 ? 113.692 128.821 116.875 1.00 43.80  ? 287 LYS R N     1 
ATOM   2119 C CA    . LYS A 1 312 ? 113.096 127.955 115.863 1.00 43.80  ? 287 LYS R CA    1 
ATOM   2120 C C     . LYS A 1 312 ? 111.738 127.439 116.319 1.00 43.80  ? 287 LYS R C     1 
ATOM   2121 O O     . LYS A 1 312 ? 110.777 127.419 115.539 1.00 43.80  ? 287 LYS R O     1 
ATOM   2122 C CB    . LYS A 1 312 ? 114.033 126.787 115.552 1.00 43.80  ? 287 LYS R CB    1 
ATOM   2123 C CG    . LYS A 1 312 ? 115.448 127.194 115.168 1.00 43.80  ? 287 LYS R CG    1 
ATOM   2124 C CD    . LYS A 1 312 ? 116.379 125.993 115.142 1.00 43.80  ? 287 LYS R CD    1 
ATOM   2125 C CE    . LYS A 1 312 ? 117.836 126.418 115.048 1.00 43.80  ? 287 LYS R CE    1 
ATOM   2126 N NZ    . LYS A 1 312 ? 118.754 125.253 114.910 1.00 43.80  ? 287 LYS R NZ    1 
ATOM   2127 N N     . PHE A 1 313 ? 111.640 127.015 117.581 1.00 42.27  ? 288 PHE R N     1 
ATOM   2128 C CA    . PHE A 1 313 ? 110.366 126.532 118.099 1.00 42.27  ? 288 PHE R CA    1 
ATOM   2129 C C     . PHE A 1 313 ? 109.319 127.638 118.100 1.00 42.27  ? 288 PHE R C     1 
ATOM   2130 O O     . PHE A 1 313 ? 108.160 127.401 117.742 1.00 42.27  ? 288 PHE R O     1 
ATOM   2131 C CB    . PHE A 1 313 ? 110.552 125.974 119.509 1.00 42.27  ? 288 PHE R CB    1 
ATOM   2132 C CG    . PHE A 1 313 ? 109.324 125.310 120.061 1.00 42.27  ? 288 PHE R CG    1 
ATOM   2133 C CD1   . PHE A 1 313 ? 109.091 123.964 119.842 1.00 42.27  ? 288 PHE R CD1   1 
ATOM   2134 C CD2   . PHE A 1 313 ? 108.398 126.035 120.791 1.00 42.27  ? 288 PHE R CD2   1 
ATOM   2135 C CE1   . PHE A 1 313 ? 107.962 123.352 120.347 1.00 42.27  ? 288 PHE R CE1   1 
ATOM   2136 C CE2   . PHE A 1 313 ? 107.267 125.429 121.297 1.00 42.27  ? 288 PHE R CE2   1 
ATOM   2137 C CZ    . PHE A 1 313 ? 107.048 124.086 121.074 1.00 42.27  ? 288 PHE R CZ    1 
ATOM   2138 N N     . LYS A 1 314 ? 109.704 128.849 118.507 1.00 45.14  ? 289 LYS R N     1 
ATOM   2139 C CA    . LYS A 1 314 ? 108.765 129.966 118.501 1.00 45.14  ? 289 LYS R CA    1 
ATOM   2140 C C     . LYS A 1 314 ? 108.269 130.250 117.090 1.00 45.14  ? 289 LYS R C     1 
ATOM   2141 O O     . LYS A 1 314 ? 107.071 130.459 116.866 1.00 45.14  ? 289 LYS R O     1 
ATOM   2142 C CB    . LYS A 1 314 ? 109.426 131.211 119.091 1.00 45.14  ? 289 LYS R CB    1 
ATOM   2143 C CG    . LYS A 1 314 ? 109.785 131.096 120.564 1.00 45.14  ? 289 LYS R CG    1 
ATOM   2144 C CD    . LYS A 1 314 ? 110.583 132.301 121.060 1.00 45.14  ? 289 LYS R CD    1 
ATOM   2145 C CE    . LYS A 1 314 ? 109.970 133.629 120.632 1.00 45.14  ? 289 LYS R CE    1 
ATOM   2146 N NZ    . LYS A 1 314 ? 108.529 133.733 120.993 1.00 45.14  ? 289 LYS R NZ    1 
ATOM   2147 N N     . GLU A 1 315 ? 109.187 130.268 116.121 1.00 49.78  ? 290 GLU R N     1 
ATOM   2148 C CA    . GLU A 1 315 ? 108.796 130.532 114.743 1.00 49.78  ? 290 GLU R CA    1 
ATOM   2149 C C     . GLU A 1 315 ? 107.849 129.456 114.229 1.00 49.78  ? 290 GLU R C     1 
ATOM   2150 O O     . GLU A 1 315 ? 106.843 129.763 113.580 1.00 49.78  ? 290 GLU R O     1 
ATOM   2151 C CB    . GLU A 1 315 ? 110.036 130.623 113.855 1.00 49.78  ? 290 GLU R CB    1 
ATOM   2152 C CG    . GLU A 1 315 ? 110.904 131.842 114.129 1.00 49.78  ? 290 GLU R CG    1 
ATOM   2153 C CD    . GLU A 1 315 ? 112.295 131.718 113.536 1.00 49.78  ? 290 GLU R CD    1 
ATOM   2154 O OE1   . GLU A 1 315 ? 112.623 130.638 113.001 1.00 49.78  ? 290 GLU R OE1   1 
ATOM   2155 O OE2   . GLU A 1 315 ? 113.060 132.702 113.605 1.00 49.78  ? 290 GLU R OE2   1 
ATOM   2156 N N     . THR A 1 316 ? 108.150 128.188 114.516 1.00 47.41  ? 291 THR R N     1 
ATOM   2157 C CA    . THR A 1 316 ? 107.280 127.107 114.066 1.00 47.41  ? 291 THR R CA    1 
ATOM   2158 C C     . THR A 1 316 ? 105.901 127.213 114.706 1.00 47.41  ? 291 THR R C     1 
ATOM   2159 O O     . THR A 1 316 ? 104.876 127.034 114.038 1.00 47.41  ? 291 THR R O     1 
ATOM   2160 C CB    . THR A 1 316 ? 107.918 125.755 114.385 1.00 47.41  ? 291 THR R CB    1 
ATOM   2161 O OG1   . THR A 1 316 ? 109.195 125.662 113.742 1.00 47.41  ? 291 THR R OG1   1 
ATOM   2162 C CG2   . THR A 1 316 ? 107.030 124.621 113.897 1.00 47.41  ? 291 THR R CG2   1 
ATOM   2163 N N     . TYR A 1 317 ? 105.858 127.504 116.007 1.00 48.33  ? 292 TYR R N     1 
ATOM   2164 C CA    . TYR A 1 317 ? 104.585 127.620 116.708 1.00 48.33  ? 292 TYR R CA    1 
ATOM   2165 C C     . TYR A 1 317 ? 103.751 128.759 116.135 1.00 48.33  ? 292 TYR R C     1 
ATOM   2166 O O     . TYR A 1 317 ? 102.541 128.620 115.924 1.00 48.33  ? 292 TYR R O     1 
ATOM   2167 C CB    . TYR A 1 317 ? 104.838 127.827 118.203 1.00 48.33  ? 292 TYR R CB    1 
ATOM   2168 C CG    . TYR A 1 317 ? 103.592 128.126 119.005 1.00 48.33  ? 292 TYR R CG    1 
ATOM   2169 C CD1   . TYR A 1 317 ? 102.687 127.121 119.316 1.00 48.33  ? 292 TYR R CD1   1 
ATOM   2170 C CD2   . TYR A 1 317 ? 103.324 129.411 119.455 1.00 48.33  ? 292 TYR R CD2   1 
ATOM   2171 C CE1   . TYR A 1 317 ? 101.547 127.388 120.049 1.00 48.33  ? 292 TYR R CE1   1 
ATOM   2172 C CE2   . TYR A 1 317 ? 102.187 129.688 120.190 1.00 48.33  ? 292 TYR R CE2   1 
ATOM   2173 C CZ    . TYR A 1 317 ? 101.302 128.672 120.484 1.00 48.33  ? 292 TYR R CZ    1 
ATOM   2174 O OH    . TYR A 1 317 ? 100.168 128.942 121.215 1.00 48.33  ? 292 TYR R OH    1 
ATOM   2175 N N     . LEU A 1 318 ? 104.389 129.901 115.874 1.00 51.58  ? 293 LEU R N     1 
ATOM   2176 C CA    . LEU A 1 318 ? 103.672 131.030 115.292 1.00 51.58  ? 293 LEU R CA    1 
ATOM   2177 C C     . LEU A 1 318 ? 103.175 130.695 113.891 1.00 51.58  ? 293 LEU R C     1 
ATOM   2178 O O     . LEU A 1 318 ? 102.066 131.080 113.503 1.00 51.58  ? 293 LEU R O     1 
ATOM   2179 C CB    . LEU A 1 318 ? 104.573 132.265 115.269 1.00 51.58  ? 293 LEU R CB    1 
ATOM   2180 C CG    . LEU A 1 318 ? 104.953 132.827 116.642 1.00 51.58  ? 293 LEU R CG    1 
ATOM   2181 C CD1   . LEU A 1 318 ? 105.980 133.939 116.500 1.00 51.58  ? 293 LEU R CD1   1 
ATOM   2182 C CD2   . LEU A 1 318 ? 103.722 133.328 117.384 1.00 51.58  ? 293 LEU R CD2   1 
ATOM   2183 N N     . LEU A 1 319 ? 103.988 129.974 113.114 1.00 53.01  ? 294 LEU R N     1 
ATOM   2184 C CA    . LEU A 1 319 ? 103.562 129.567 111.779 1.00 53.01  ? 294 LEU R CA    1 
ATOM   2185 C C     . LEU A 1 319 ? 102.326 128.680 111.844 1.00 53.01  ? 294 LEU R C     1 
ATOM   2186 O O     . LEU A 1 319 ? 101.393 128.840 111.048 1.00 53.01  ? 294 LEU R O     1 
ATOM   2187 C CB    . LEU A 1 319 ? 104.702 128.837 111.066 1.00 53.01  ? 294 LEU R CB    1 
ATOM   2188 C CG    . LEU A 1 319 ? 105.883 129.699 110.616 1.00 53.01  ? 294 LEU R CG    1 
ATOM   2189 C CD1   . LEU A 1 319 ? 107.089 128.827 110.308 1.00 53.01  ? 294 LEU R CD1   1 
ATOM   2190 C CD2   . LEU A 1 319 ? 105.505 130.538 109.405 1.00 53.01  ? 294 LEU R CD2   1 
ATOM   2191 N N     . ILE A 1 320 ? 102.301 127.742 112.784 1.00 50.24  ? 295 ILE R N     1 
ATOM   2192 C CA    . ILE A 1 320 ? 101.169 126.837 112.937 1.00 50.24  ? 295 ILE R CA    1 
ATOM   2193 C C     . ILE A 1 320 ? 100.000 127.580 113.572 1.00 50.24  ? 295 ILE R C     1 
ATOM   2194 O O     . ILE A 1 320 ? 98.840  127.226 113.362 1.00 50.24  ? 295 ILE R O     1 
ATOM   2195 C CB    . ILE A 1 320 ? 101.553 125.601 113.772 1.00 50.24  ? 295 ILE R CB    1 
ATOM   2196 C CG1   . ILE A 1 320 ? 102.689 124.830 113.093 1.00 50.24  ? 295 ILE R CG1   1 
ATOM   2197 C CG2   . ILE A 1 320 ? 100.344 124.697 113.970 1.00 50.24  ? 295 ILE R CG2   1 
ATOM   2198 C CD1   . ILE A 1 320 ? 103.416 123.875 114.015 1.00 50.24  ? 295 ILE R CD1   1 
ATOM   2199 N N     . THR B 2 83  ? 104.215 91.069  103.332 1.00 16.64  ? 4   THR A N     1 
ATOM   2200 C CA    . THR B 2 83  ? 104.341 90.041  102.306 1.00 16.64  ? 4   THR A CA    1 
ATOM   2201 C C     . THR B 2 83  ? 105.549 90.314  101.417 1.00 16.64  ? 4   THR A C     1 
ATOM   2202 O O     . THR B 2 83  ? 105.487 91.139  100.506 1.00 16.64  ? 4   THR A O     1 
ATOM   2203 C CB    . THR B 2 83  ? 103.079 89.961  101.428 1.00 16.64  ? 4   THR A CB    1 
ATOM   2204 O OG1   . THR B 2 83  ? 101.926 89.765  102.258 1.00 16.64  ? 4   THR A OG1   1 
ATOM   2205 C CG2   . THR B 2 83  ? 103.188 88.813  100.434 1.00 16.64  ? 4   THR A CG2   1 
ATOM   2206 N N     . LEU B 2 84  ? 106.648 89.616  101.689 1.00 11.85  ? 5   LEU A N     1 
ATOM   2207 C CA    . LEU B 2 84  ? 107.879 89.755  100.928 1.00 11.85  ? 5   LEU A CA    1 
ATOM   2208 C C     . LEU B 2 84  ? 108.277 88.411  100.338 1.00 11.85  ? 5   LEU A C     1 
ATOM   2209 O O     . LEU B 2 84  ? 108.147 87.367  100.984 1.00 11.85  ? 5   LEU A O     1 
ATOM   2210 C CB    . LEU B 2 84  ? 109.024 90.288  101.804 1.00 11.85  ? 5   LEU A CB    1 
ATOM   2211 C CG    . LEU B 2 84  ? 109.034 91.780  102.153 1.00 11.85  ? 5   LEU A CG    1 
ATOM   2212 C CD1   . LEU B 2 84  ? 110.379 92.165  102.743 1.00 11.85  ? 5   LEU A CD1   1 
ATOM   2213 C CD2   . LEU B 2 84  ? 108.718 92.648  100.945 1.00 11.85  ? 5   LEU A CD2   1 
ATOM   2214 N N     . SER B 2 85  ? 108.758 88.447  99.100  1.00 13.64  ? 6   SER A N     1 
ATOM   2215 C CA    . SER B 2 85  ? 109.310 87.260  98.471  1.00 13.64  ? 6   SER A CA    1 
ATOM   2216 C C     . SER B 2 85  ? 110.743 87.035  98.948  1.00 13.64  ? 6   SER A C     1 
ATOM   2217 O O     . SER B 2 85  ? 111.368 87.902  99.562  1.00 13.64  ? 6   SER A O     1 
ATOM   2218 C CB    . SER B 2 85  ? 109.268 87.387  96.951  1.00 13.64  ? 6   SER A CB    1 
ATOM   2219 O OG    . SER B 2 85  ? 110.126 88.420  96.506  1.00 13.64  ? 6   SER A OG    1 
ATOM   2220 N N     . ALA B 2 86  ? 111.266 85.845  98.654  1.00 13.38  ? 7   ALA A N     1 
ATOM   2221 C CA    . ALA B 2 86  ? 112.615 85.508  99.088  1.00 13.38  ? 7   ALA A CA    1 
ATOM   2222 C C     . ALA B 2 86  ? 113.646 86.508  98.586  1.00 13.38  ? 7   ALA A C     1 
ATOM   2223 O O     . ALA B 2 86  ? 114.662 86.722  99.257  1.00 13.38  ? 7   ALA A O     1 
ATOM   2224 C CB    . ALA B 2 86  ? 112.982 84.104  98.613  1.00 13.38  ? 7   ALA A CB    1 
ATOM   2225 N N     . GLU B 2 87  ? 113.410 87.125  97.429  1.00 12.22  ? 8   GLU A N     1 
ATOM   2226 C CA    . GLU B 2 87  ? 114.353 88.083  96.866  1.00 12.22  ? 8   GLU A CA    1 
ATOM   2227 C C     . GLU B 2 87  ? 114.110 89.499  97.370  1.00 12.22  ? 8   GLU A C     1 
ATOM   2228 O O     . GLU B 2 87  ? 115.062 90.271  97.523  1.00 12.22  ? 8   GLU A O     1 
ATOM   2229 C CB    . GLU B 2 87  ? 114.281 88.053  95.338  1.00 12.22  ? 8   GLU A CB    1 
ATOM   2230 C CG    . GLU B 2 87  ? 114.494 86.669  94.746  1.00 12.22  ? 8   GLU A CG    1 
ATOM   2231 C CD    . GLU B 2 87  ? 115.207 86.697  93.409  1.00 12.22  ? 8   GLU A CD    1 
ATOM   2232 O OE1   . GLU B 2 87  ? 116.007 87.626  93.175  1.00 12.22  ? 8   GLU A OE1   1 
ATOM   2233 O OE2   . GLU B 2 87  ? 114.974 85.783  92.593  1.00 12.22  ? 8   GLU A OE2   1 
ATOM   2234 N N     . ASP B 2 88  ? 112.852 89.860  97.635  1.00 10.77  ? 9   ASP A N     1 
ATOM   2235 C CA    . ASP B 2 88  ? 112.572 91.187  98.172  1.00 10.77  ? 9   ASP A CA    1 
ATOM   2236 C C     . ASP B 2 88  ? 113.175 91.356  99.559  1.00 10.77  ? 9   ASP A C     1 
ATOM   2237 O O     . ASP B 2 88  ? 113.564 92.464  99.942  1.00 10.77  ? 9   ASP A O     1 
ATOM   2238 C CB    . ASP B 2 88  ? 111.066 91.433  98.214  1.00 10.77  ? 9   ASP A CB    1 
ATOM   2239 C CG    . ASP B 2 88  ? 110.426 91.371  96.844  1.00 10.77  ? 9   ASP A CG    1 
ATOM   2240 O OD1   . ASP B 2 88  ? 111.166 91.334  95.839  1.00 10.77  ? 9   ASP A OD1   1 
ATOM   2241 O OD2   . ASP B 2 88  ? 109.181 91.361  96.774  1.00 10.77  ? 9   ASP A OD2   1 
ATOM   2242 N N     . LYS B 2 89  ? 113.255 90.273  100.331 1.00 9.88   ? 10  LYS A N     1 
ATOM   2243 C CA    . LYS B 2 89  ? 113.869 90.358  101.652 1.00 9.88   ? 10  LYS A CA    1 
ATOM   2244 C C     . LYS B 2 89  ? 115.351 90.699  101.546 1.00 9.88   ? 10  LYS A C     1 
ATOM   2245 O O     . LYS B 2 89  ? 115.867 91.516  102.318 1.00 9.88   ? 10  LYS A O     1 
ATOM   2246 C CB    . LYS B 2 89  ? 113.663 89.043  102.402 1.00 9.88   ? 10  LYS A CB    1 
ATOM   2247 C CG    . LYS B 2 89  ? 112.203 88.736  102.688 1.00 9.88   ? 10  LYS A CG    1 
ATOM   2248 C CD    . LYS B 2 89  ? 112.046 87.514  103.573 1.00 9.88   ? 10  LYS A CD    1 
ATOM   2249 C CE    . LYS B 2 89  ? 110.610 87.350  104.043 1.00 9.88   ? 10  LYS A CE    1 
ATOM   2250 N NZ    . LYS B 2 89  ? 109.941 86.181  103.410 1.00 9.88   ? 10  LYS A NZ    1 
ATOM   2251 N N     . ALA B 2 90  ? 116.050 90.094  100.584 1.00 8.51   ? 11  ALA A N     1 
ATOM   2252 C CA    . ALA B 2 90  ? 117.456 90.422  100.378 1.00 8.51   ? 11  ALA A CA    1 
ATOM   2253 C C     . ALA B 2 90  ? 117.620 91.849  99.869  1.00 8.51   ? 11  ALA A C     1 
ATOM   2254 O O     . ALA B 2 90  ? 118.568 92.546  100.249 1.00 8.51   ? 11  ALA A O     1 
ATOM   2255 C CB    . ALA B 2 90  ? 118.086 89.428  99.405  1.00 8.51   ? 11  ALA A CB    1 
ATOM   2256 N N     . ALA B 2 91  ? 116.708 92.303  99.008  1.00 7.17   ? 12  ALA A N     1 
ATOM   2257 C CA    . ALA B 2 91  ? 116.753 93.685  98.544  1.00 7.17   ? 12  ALA A CA    1 
ATOM   2258 C C     . ALA B 2 91  ? 116.555 94.654  99.702  1.00 7.17   ? 12  ALA A C     1 
ATOM   2259 O O     . ALA B 2 91  ? 117.225 95.689  99.782  1.00 7.17   ? 12  ALA A O     1 
ATOM   2260 C CB    . ALA B 2 91  ? 115.695 93.909  97.464  1.00 7.17   ? 12  ALA A CB    1 
ATOM   2261 N N     . VAL B 2 92  ? 115.633 94.335  100.612 1.00 6.92   ? 13  VAL A N     1 
ATOM   2262 C CA    . VAL B 2 92  ? 115.407 95.186  101.776 1.00 6.92   ? 13  VAL A CA    1 
ATOM   2263 C C     . VAL B 2 92  ? 116.629 95.177  102.683 1.00 6.92   ? 13  VAL A C     1 
ATOM   2264 O O     . VAL B 2 92  ? 116.995 96.204  103.263 1.00 6.92   ? 13  VAL A O     1 
ATOM   2265 C CB    . VAL B 2 92  ? 114.139 94.739  102.526 1.00 6.92   ? 13  VAL A CB    1 
ATOM   2266 C CG1   . VAL B 2 92  ? 114.047 95.429  103.874 1.00 6.92   ? 13  VAL A CG1   1 
ATOM   2267 C CG2   . VAL B 2 92  ? 112.902 95.035  101.698 1.00 6.92   ? 13  VAL A CG2   1 
ATOM   2268 N N     . GLU B 2 93  ? 117.273 94.019  102.831 1.00 7.69   ? 14  GLU A N     1 
ATOM   2269 C CA    . GLU B 2 93  ? 118.510 93.967  103.604 1.00 7.69   ? 14  GLU A CA    1 
ATOM   2270 C C     . GLU B 2 93  ? 119.584 94.852  102.987 1.00 7.69   ? 14  GLU A C     1 
ATOM   2271 O O     . GLU B 2 93  ? 120.299 95.563  103.706 1.00 7.69   ? 14  GLU A O     1 
ATOM   2272 C CB    . GLU B 2 93  ? 119.005 92.525  103.698 1.00 7.69   ? 14  GLU A CB    1 
ATOM   2273 C CG    . GLU B 2 93  ? 118.619 91.821  104.981 1.00 7.69   ? 14  GLU A CG    1 
ATOM   2274 C CD    . GLU B 2 93  ? 119.212 90.432  105.079 1.00 7.69   ? 14  GLU A CD    1 
ATOM   2275 O OE1   . GLU B 2 93  ? 118.490 89.504  105.499 1.00 7.69   ? 14  GLU A OE1   1 
ATOM   2276 O OE2   . GLU B 2 93  ? 120.402 90.269  104.736 1.00 7.69   ? 14  GLU A OE2   1 
ATOM   2277 N N     . ARG B 2 94  ? 119.708 94.825  101.659 1.00 6.40   ? 15  ARG A N     1 
ATOM   2278 C CA    . ARG B 2 94  ? 120.675 95.681  100.980 1.00 6.40   ? 15  ARG A CA    1 
ATOM   2279 C C     . ARG B 2 94  ? 120.334 97.154  101.185 1.00 6.40   ? 15  ARG A C     1 
ATOM   2280 O O     . ARG B 2 94  ? 121.222 97.985  101.406 1.00 6.40   ? 15  ARG A O     1 
ATOM   2281 C CB    . ARG B 2 94  ? 120.715 95.327  99.493  1.00 6.40   ? 15  ARG A CB    1 
ATOM   2282 C CG    . ARG B 2 94  ? 121.706 96.128  98.662  1.00 6.40   ? 15  ARG A CG    1 
ATOM   2283 C CD    . ARG B 2 94  ? 121.408 95.977  97.181  1.00 6.40   ? 15  ARG A CD    1 
ATOM   2284 N NE    . ARG B 2 94  ? 122.193 96.886  96.354  1.00 6.40   ? 15  ARG A NE    1 
ATOM   2285 C CZ    . ARG B 2 94  ? 123.486 96.742  96.099  1.00 6.40   ? 15  ARG A CZ    1 
ATOM   2286 N NH1   . ARG B 2 94  ? 124.182 95.734  96.598  1.00 6.40   ? 15  ARG A NH1   1 
ATOM   2287 N NH2   . ARG B 2 94  ? 124.095 97.632  95.322  1.00 6.40   ? 15  ARG A NH2   1 
ATOM   2288 N N     . SER B 2 95  ? 119.046 97.494  101.114 1.00 6.08   ? 16  SER A N     1 
ATOM   2289 C CA    . SER B 2 95  ? 118.631 98.876  101.338 1.00 6.08   ? 16  SER A CA    1 
ATOM   2290 C C     . SER B 2 95  ? 118.950 99.325  102.758 1.00 6.08   ? 16  SER A C     1 
ATOM   2291 O O     . SER B 2 95  ? 119.373 100.464 102.975 1.00 6.08   ? 16  SER A O     1 
ATOM   2292 C CB    . SER B 2 95  ? 117.137 99.028  101.058 1.00 6.08   ? 16  SER A CB    1 
ATOM   2293 O OG    . SER B 2 95  ? 116.821 98.593  99.749  1.00 6.08   ? 16  SER A OG    1 
ATOM   2294 N N     . LYS B 2 96  ? 118.736 98.450  103.742 1.00 7.20   ? 17  LYS A N     1 
ATOM   2295 C CA    . LYS B 2 96  ? 119.062 98.792  105.124 1.00 7.20   ? 17  LYS A CA    1 
ATOM   2296 C C     . LYS B 2 96  ? 120.564 98.966  105.307 1.00 7.20   ? 17  LYS A C     1 
ATOM   2297 O O     . LYS B 2 96  ? 121.008 99.850  106.048 1.00 7.20   ? 17  LYS A O     1 
ATOM   2298 C CB    . LYS B 2 96  ? 118.527 97.719  106.072 1.00 7.20   ? 17  LYS A CB    1 
ATOM   2299 C CG    . LYS B 2 96  ? 117.010 97.584  106.082 1.00 7.20   ? 17  LYS A CG    1 
ATOM   2300 C CD    . LYS B 2 96  ? 116.327 98.828  106.621 1.00 7.20   ? 17  LYS A CD    1 
ATOM   2301 C CE    . LYS B 2 96  ? 114.816 98.674  106.614 1.00 7.20   ? 17  LYS A CE    1 
ATOM   2302 N NZ    . LYS B 2 96  ? 114.357 97.624  107.564 1.00 7.20   ? 17  LYS A NZ    1 
ATOM   2303 N N     . MET B 2 97  ? 121.364 98.125  104.650 1.00 8.94   ? 18  MET A N     1 
ATOM   2304 C CA    . MET B 2 97  ? 122.812 98.306  104.705 1.00 8.94   ? 18  MET A CA    1 
ATOM   2305 C C     . MET B 2 97  ? 123.219 99.640  104.091 1.00 8.94   ? 18  MET A C     1 
ATOM   2306 O O     . MET B 2 97  ? 124.095 100.337 104.620 1.00 8.94   ? 18  MET A O     1 
ATOM   2307 C CB    . MET B 2 97  ? 123.508 97.150  103.990 1.00 8.94   ? 18  MET A CB    1 
ATOM   2308 C CG    . MET B 2 97  ? 124.976 96.995  104.356 1.00 8.94   ? 18  MET A CG    1 
ATOM   2309 S SD    . MET B 2 97  ? 125.565 95.295  104.246 1.00 8.94   ? 18  MET A SD    1 
ATOM   2310 C CE    . MET B 2 97  ? 124.495 94.485  105.431 1.00 8.94   ? 18  MET A CE    1 
ATOM   2311 N N     . ILE B 2 98  ? 122.593 100.012 102.973 1.00 6.97   ? 19  ILE A N     1 
ATOM   2312 C CA    . ILE B 2 98  ? 122.876 101.305 102.360 1.00 6.97   ? 19  ILE A CA    1 
ATOM   2313 C C     . ILE B 2 98  ? 122.464 102.437 103.292 1.00 6.97   ? 19  ILE A C     1 
ATOM   2314 O O     . ILE B 2 98  ? 123.144 103.463 103.378 1.00 6.97   ? 19  ILE A O     1 
ATOM   2315 C CB    . ILE B 2 98  ? 122.181 101.413 100.990 1.00 6.97   ? 19  ILE A CB    1 
ATOM   2316 C CG1   . ILE B 2 98  ? 122.837 100.464 99.987  1.00 6.97   ? 19  ILE A CG1   1 
ATOM   2317 C CG2   . ILE B 2 98  ? 122.255 102.838 100.466 1.00 6.97   ? 19  ILE A CG2   1 
ATOM   2318 C CD1   . ILE B 2 98  ? 121.975 100.142 98.795  1.00 6.97   ? 19  ILE A CD1   1 
ATOM   2319 N N     . ASP B 2 99  ? 121.335 102.281 103.987 1.00 7.54   ? 20  ASP A N     1 
ATOM   2320 C CA    . ASP B 2 99  ? 120.912 103.285 104.959 1.00 7.54   ? 20  ASP A CA    1 
ATOM   2321 C C     . ASP B 2 99  ? 121.952 103.445 106.057 1.00 7.54   ? 20  ASP A C     1 
ATOM   2322 O O     . ASP B 2 99  ? 122.287 104.565 106.460 1.00 7.54   ? 20  ASP A O     1 
ATOM   2323 C CB    . ASP B 2 99  ? 119.567 102.892 105.570 1.00 7.54   ? 20  ASP A CB    1 
ATOM   2324 C CG    . ASP B 2 99  ? 118.447 102.879 104.558 1.00 7.54   ? 20  ASP A CG    1 
ATOM   2325 O OD1   . ASP B 2 99  ? 118.620 103.474 103.478 1.00 7.54   ? 20  ASP A OD1   1 
ATOM   2326 O OD2   . ASP B 2 99  ? 117.392 102.275 104.843 1.00 7.54   ? 20  ASP A OD2   1 
ATOM   2327 N N     . ARG B 2 100 ? 122.460 102.323 106.568 1.00 10.06  ? 21  ARG A N     1 
ATOM   2328 C CA    . ARG B 2 100 ? 123.490 102.378 107.599 1.00 10.06  ? 21  ARG A CA    1 
ATOM   2329 C C     . ARG B 2 100 ? 124.729 103.099 107.088 1.00 10.06  ? 21  ARG A C     1 
ATOM   2330 O O     . ARG B 2 100 ? 125.310 103.933 107.794 1.00 10.06  ? 21  ARG A O     1 
ATOM   2331 C CB    . ARG B 2 100 ? 123.845 100.963 108.053 1.00 10.06  ? 21  ARG A CB    1 
ATOM   2332 C CG    . ARG B 2 100 ? 122.834 100.341 109.003 1.00 10.06  ? 21  ARG A CG    1 
ATOM   2333 C CD    . ARG B 2 100 ? 123.504 99.411  110.004 1.00 10.06  ? 21  ARG A CD    1 
ATOM   2334 N NE    . ARG B 2 100 ? 123.930 98.159  109.389 1.00 10.06  ? 21  ARG A NE    1 
ATOM   2335 C CZ    . ARG B 2 100 ? 123.105 97.211  108.965 1.00 10.06  ? 21  ARG A CZ    1 
ATOM   2336 N NH1   . ARG B 2 100 ? 121.793 97.332  109.078 1.00 10.06  ? 21  ARG A NH1   1 
ATOM   2337 N NH2   . ARG B 2 100 ? 123.611 96.112  108.411 1.00 10.06  ? 21  ARG A NH2   1 
ATOM   2338 N N     . ASN B 2 101 ? 125.146 102.790 105.859 1.00 10.53  ? 22  ASN A N     1 
ATOM   2339 C CA    . ASN B 2 101 ? 126.323 103.440 105.292 1.00 10.53  ? 22  ASN A CA    1 
ATOM   2340 C C     . ASN B 2 101 ? 126.097 104.937 105.116 1.00 10.53  ? 22  ASN A C     1 
ATOM   2341 O O     . ASN B 2 101 ? 126.986 105.748 105.406 1.00 10.53  ? 22  ASN A O     1 
ATOM   2342 C CB    . ASN B 2 101 ? 126.684 102.786 103.959 1.00 10.53  ? 22  ASN A CB    1 
ATOM   2343 C CG    . ASN B 2 101 ? 127.500 101.521 104.137 1.00 10.53  ? 22  ASN A CG    1 
ATOM   2344 O OD1   . ASN B 2 101 ? 127.050 100.426 103.804 1.00 10.53  ? 22  ASN A OD1   1 
ATOM   2345 N ND2   . ASN B 2 101 ? 128.708 101.667 104.668 1.00 10.53  ? 22  ASN A ND2   1 
ATOM   2346 N N     . LEU B 2 102 ? 124.910 105.323 104.647 1.00 8.34   ? 23  LEU A N     1 
ATOM   2347 C CA    . LEU B 2 102 ? 124.603 106.739 104.480 1.00 8.34   ? 23  LEU A CA    1 
ATOM   2348 C C     . LEU B 2 102 ? 124.628 107.462 105.819 1.00 8.34   ? 23  LEU A C     1 
ATOM   2349 O O     . LEU B 2 102 ? 125.173 108.563 105.931 1.00 8.34   ? 23  LEU A O     1 
ATOM   2350 C CB    . LEU B 2 102 ? 123.242 106.908 103.808 1.00 8.34   ? 23  LEU A CB    1 
ATOM   2351 C CG    . LEU B 2 102 ? 123.152 106.493 102.342 1.00 8.34   ? 23  LEU A CG    1 
ATOM   2352 C CD1   . LEU B 2 102 ? 121.709 106.516 101.890 1.00 8.34   ? 23  LEU A CD1   1 
ATOM   2353 C CD2   . LEU B 2 102 ? 124.004 107.392 101.466 1.00 8.34   ? 23  LEU A CD2   1 
ATOM   2354 N N     . ARG B 2 103 ? 124.037 106.859 106.851 1.00 10.90  ? 24  ARG A N     1 
ATOM   2355 C CA    . ARG B 2 103 ? 124.034 107.503 108.159 1.00 10.90  ? 24  ARG A CA    1 
ATOM   2356 C C     . ARG B 2 103 ? 125.448 107.641 108.708 1.00 10.90  ? 24  ARG A C     1 
ATOM   2357 O O     . ARG B 2 103 ? 125.817 108.701 109.230 1.00 10.90  ? 24  ARG A O     1 
ATOM   2358 C CB    . ARG B 2 103 ? 123.152 106.721 109.132 1.00 10.90  ? 24  ARG A CB    1 
ATOM   2359 C CG    . ARG B 2 103 ? 121.661 106.890 108.873 1.00 10.90  ? 24  ARG A CG    1 
ATOM   2360 C CD    . ARG B 2 103 ? 120.827 106.381 110.037 1.00 10.90  ? 24  ARG A CD    1 
ATOM   2361 N NE    . ARG B 2 103 ? 120.831 104.925 110.124 1.00 10.90  ? 24  ARG A NE    1 
ATOM   2362 C CZ    . ARG B 2 103 ? 119.920 104.132 109.575 1.00 10.90  ? 24  ARG A CZ    1 
ATOM   2363 N NH1   . ARG B 2 103 ? 118.910 104.618 108.871 1.00 10.90  ? 24  ARG A NH1   1 
ATOM   2364 N NH2   . ARG B 2 103 ? 120.026 102.817 109.734 1.00 10.90  ? 24  ARG A NH2   1 
ATOM   2365 N N     . GLU B 2 104 ? 126.264 106.591 108.584 1.00 13.87  ? 25  GLU A N     1 
ATOM   2366 C CA    . GLU B 2 104 ? 127.602 106.647 109.160 1.00 13.87  ? 25  GLU A CA    1 
ATOM   2367 C C     . GLU B 2 104 ? 128.537 107.557 108.373 1.00 13.87  ? 25  GLU A C     1 
ATOM   2368 O O     . GLU B 2 104 ? 129.513 108.053 108.945 1.00 13.87  ? 25  GLU A O     1 
ATOM   2369 C CB    . GLU B 2 104 ? 128.205 105.244 109.266 1.00 13.87  ? 25  GLU A CB    1 
ATOM   2370 C CG    . GLU B 2 104 ? 128.380 104.523 107.945 1.00 13.87  ? 25  GLU A CG    1 
ATOM   2371 C CD    . GLU B 2 104 ? 129.686 104.863 107.247 1.00 13.87  ? 25  GLU A CD    1 
ATOM   2372 O OE1   . GLU B 2 104 ? 130.619 105.350 107.920 1.00 13.87  ? 25  GLU A OE1   1 
ATOM   2373 O OE2   . GLU B 2 104 ? 129.779 104.639 106.021 1.00 13.87  ? 25  GLU A OE2   1 
ATOM   2374 N N     . ASP B 2 105 ? 128.274 107.791 107.084 1.00 13.87  ? 26  ASP A N     1 
ATOM   2375 C CA    . ASP B 2 105 ? 129.078 108.762 106.349 1.00 13.87  ? 26  ASP A CA    1 
ATOM   2376 C C     . ASP B 2 105 ? 128.576 110.187 106.539 1.00 13.87  ? 26  ASP A C     1 
ATOM   2377 O O     . ASP B 2 105 ? 129.381 111.125 106.548 1.00 13.87  ? 26  ASP A O     1 
ATOM   2378 C CB    . ASP B 2 105 ? 129.127 108.400 104.856 1.00 13.87  ? 26  ASP A CB    1 
ATOM   2379 C CG    . ASP B 2 105 ? 127.809 108.634 104.130 1.00 13.87  ? 26  ASP A CG    1 
ATOM   2380 O OD1   . ASP B 2 105 ? 126.993 109.466 104.572 1.00 13.87  ? 26  ASP A OD1   1 
ATOM   2381 O OD2   . ASP B 2 105 ? 127.593 107.974 103.092 1.00 13.87  ? 26  ASP A OD2   1 
ATOM   2382 N N     . GLY B 2 106 ? 127.267 110.375 106.711 1.00 14.70  ? 27  GLY A N     1 
ATOM   2383 C CA    . GLY B 2 106 ? 126.761 111.692 107.053 1.00 14.70  ? 27  GLY A CA    1 
ATOM   2384 C C     . GLY B 2 106 ? 127.238 112.148 108.417 1.00 14.70  ? 27  GLY A C     1 
ATOM   2385 O O     . GLY B 2 106 ? 127.542 113.328 108.616 1.00 14.70  ? 27  GLY A O     1 
ATOM   2386 N N     . GLU B 2 107 ? 127.305 111.224 109.378 1.00 19.63  ? 28  GLU A N     1 
ATOM   2387 C CA    . GLU B 2 107 ? 127.919 111.556 110.658 1.00 19.63  ? 28  GLU A CA    1 
ATOM   2388 C C     . GLU B 2 107 ? 129.332 112.084 110.454 1.00 19.63  ? 28  GLU A C     1 
ATOM   2389 O O     . GLU B 2 107 ? 129.668 113.175 110.926 1.00 19.63  ? 28  GLU A O     1 
ATOM   2390 C CB    . GLU B 2 107 ? 127.934 110.332 111.571 1.00 19.63  ? 28  GLU A CB    1 
ATOM   2391 C CG    . GLU B 2 107 ? 126.588 109.992 112.182 1.00 19.63  ? 28  GLU A CG    1 
ATOM   2392 C CD    . GLU B 2 107 ? 126.696 108.953 113.281 1.00 19.63  ? 28  GLU A CD    1 
ATOM   2393 O OE1   . GLU B 2 107 ? 127.434 109.196 114.259 1.00 19.63  ? 28  GLU A OE1   1 
ATOM   2394 O OE2   . GLU B 2 107 ? 126.047 107.892 113.168 1.00 19.63  ? 28  GLU A OE2   1 
ATOM   2395 N N     . LYS B 2 108 ? 130.162 111.343 109.721 1.00 20.19  ? 29  LYS A N     1 
ATOM   2396 C CA    . LYS B 2 108 ? 131.511 111.787 109.401 1.00 20.19  ? 29  LYS A CA    1 
ATOM   2397 C C     . LYS B 2 108 ? 131.539 113.144 108.711 1.00 20.19  ? 29  LYS A C     1 
ATOM   2398 O O     . LYS B 2 108 ? 132.460 113.928 108.959 1.00 20.19  ? 29  LYS A O     1 
ATOM   2399 C CB    . LYS B 2 108 ? 132.197 110.751 108.509 1.00 20.19  ? 29  LYS A CB    1 
ATOM   2400 C CG    . LYS B 2 108 ? 133.633 111.086 108.146 1.00 20.19  ? 29  LYS A CG    1 
ATOM   2401 C CD    . LYS B 2 108 ? 134.257 109.985 107.307 1.00 20.19  ? 29  LYS A CD    1 
ATOM   2402 C CE    . LYS B 2 108 ? 135.713 110.282 106.996 1.00 20.19  ? 29  LYS A CE    1 
ATOM   2403 N NZ    . LYS B 2 108 ? 135.855 111.452 106.085 1.00 20.19  ? 29  LYS A NZ    1 
ATOM   2404 N N     . ALA B 2 109 ? 130.560 113.436 107.858 1.00 20.35  ? 30  ALA A N     1 
ATOM   2405 C CA    . ALA B 2 109 ? 130.495 114.714 107.165 1.00 20.35  ? 30  ALA A CA    1 
ATOM   2406 C C     . ALA B 2 109 ? 129.939 115.838 108.031 1.00 20.35  ? 30  ALA A C     1 
ATOM   2407 O O     . ALA B 2 109 ? 130.033 117.004 107.635 1.00 20.35  ? 30  ALA A O     1 
ATOM   2408 C CB    . ALA B 2 109 ? 129.639 114.587 105.899 1.00 20.35  ? 30  ALA A CB    1 
ATOM   2409 N N     . ALA B 2 110 ? 129.362 115.522 109.190 1.00 22.58  ? 31  ALA A N     1 
ATOM   2410 C CA    . ALA B 2 110 ? 128.791 116.527 110.077 1.00 22.58  ? 31  ALA A CA    1 
ATOM   2411 C C     . ALA B 2 110 ? 129.756 116.980 111.167 1.00 22.58  ? 31  ALA A C     1 
ATOM   2412 O O     . ALA B 2 110 ? 129.436 117.911 111.912 1.00 22.58  ? 31  ALA A O     1 
ATOM   2413 C CB    . ALA B 2 110 ? 127.505 115.995 110.711 1.00 22.58  ? 31  ALA A CB    1 
ATOM   2414 N N     . ARG B 2 111 ? 130.927 116.351 111.283 1.00 24.77  ? 32  ARG A N     1 
ATOM   2415 C CA    . ARG B 2 111 ? 131.952 116.784 112.224 1.00 24.77  ? 32  ARG A CA    1 
ATOM   2416 C C     . ARG B 2 111 ? 133.012 117.657 111.570 1.00 24.77  ? 32  ARG A C     1 
ATOM   2417 O O     . ARG B 2 111 ? 134.030 117.953 112.205 1.00 24.77  ? 32  ARG A O     1 
ATOM   2418 C CB    . ARG B 2 111 ? 132.637 115.576 112.882 1.00 24.77  ? 32  ARG A CB    1 
ATOM   2419 C CG    . ARG B 2 111 ? 131.826 114.879 113.967 1.00 24.77  ? 32  ARG A CG    1 
ATOM   2420 C CD    . ARG B 2 111 ? 130.659 114.121 113.381 1.00 24.77  ? 32  ARG A CD    1 
ATOM   2421 N NE    . ARG B 2 111 ? 129.992 113.266 114.357 1.00 24.77  ? 32  ARG A NE    1 
ATOM   2422 C CZ    . ARG B 2 111 ? 130.322 112.005 114.605 1.00 24.77  ? 32  ARG A CZ    1 
ATOM   2423 N NH1   . ARG B 2 111 ? 131.325 111.412 113.977 1.00 24.77  ? 32  ARG A NH1   1 
ATOM   2424 N NH2   . ARG B 2 111 ? 129.626 111.319 115.507 1.00 24.77  ? 32  ARG A NH2   1 
ATOM   2425 N N     . GLU B 2 112 ? 132.802 118.077 110.328 1.00 25.37  ? 33  GLU A N     1 
ATOM   2426 C CA    . GLU B 2 112 ? 133.815 118.765 109.544 1.00 25.37  ? 33  GLU A CA    1 
ATOM   2427 C C     . GLU B 2 112 ? 133.432 120.227 109.366 1.00 25.37  ? 33  GLU A C     1 
ATOM   2428 O O     . GLU B 2 112 ? 132.279 120.545 109.057 1.00 25.37  ? 33  GLU A O     1 
ATOM   2429 C CB    . GLU B 2 112 ? 133.983 118.084 108.186 1.00 25.37  ? 33  GLU A CB    1 
ATOM   2430 C CG    . GLU B 2 112 ? 134.570 116.685 108.298 1.00 25.37  ? 33  GLU A CG    1 
ATOM   2431 C CD    . GLU B 2 112 ? 134.718 115.996 106.958 1.00 25.37  ? 33  GLU A CD    1 
ATOM   2432 O OE1   . GLU B 2 112 ? 134.247 116.555 105.948 1.00 25.37  ? 33  GLU A OE1   1 
ATOM   2433 O OE2   . GLU B 2 112 ? 135.306 114.895 106.915 1.00 25.37  ? 33  GLU A OE2   1 
ATOM   2434 N N     . VAL B 2 113 ? 134.406 121.110 109.567 1.00 22.09  ? 34  VAL A N     1 
ATOM   2435 C CA    . VAL B 2 113 ? 134.183 122.550 109.503 1.00 22.09  ? 34  VAL A CA    1 
ATOM   2436 C C     . VAL B 2 113 ? 134.287 122.990 108.046 1.00 22.09  ? 34  VAL A C     1 
ATOM   2437 O O     . VAL B 2 113 ? 135.354 122.902 107.436 1.00 22.09  ? 34  VAL A O     1 
ATOM   2438 C CB    . VAL B 2 113 ? 135.183 123.307 110.383 1.00 22.09  ? 34  VAL A CB    1 
ATOM   2439 C CG1   . VAL B 2 113 ? 135.040 124.803 110.189 1.00 22.09  ? 34  VAL A CG1   1 
ATOM   2440 C CG2   . VAL B 2 113 ? 134.986 122.938 111.843 1.00 22.09  ? 34  VAL A CG2   1 
ATOM   2441 N N     . LYS B 2 114 ? 133.182 123.478 107.493 1.00 20.86  ? 35  LYS A N     1 
ATOM   2442 C CA    . LYS B 2 114 ? 133.151 123.948 106.114 1.00 20.86  ? 35  LYS A CA    1 
ATOM   2443 C C     . LYS B 2 114 ? 133.343 125.460 106.087 1.00 20.86  ? 35  LYS A C     1 
ATOM   2444 O O     . LYS B 2 114 ? 132.562 126.199 106.695 1.00 20.86  ? 35  LYS A O     1 
ATOM   2445 C CB    . LYS B 2 114 ? 131.829 123.559 105.459 1.00 20.86  ? 35  LYS A CB    1 
ATOM   2446 C CG    . LYS B 2 114 ? 131.698 122.073 105.174 1.00 20.86  ? 35  LYS A CG    1 
ATOM   2447 C CD    . LYS B 2 114 ? 130.573 121.784 104.195 1.00 20.86  ? 35  LYS A CD    1 
ATOM   2448 C CE    . LYS B 2 114 ? 129.250 122.366 104.668 1.00 20.86  ? 35  LYS A CE    1 
ATOM   2449 N NZ    . LYS B 2 114 ? 128.107 121.889 103.843 1.00 20.86  ? 35  LYS A NZ    1 
ATOM   2450 N N     . LEU B 2 115 ? 134.375 125.920 105.383 1.00 21.02  ? 36  LEU A N     1 
ATOM   2451 C CA    . LEU B 2 115 ? 134.720 127.334 105.319 1.00 21.02  ? 36  LEU A CA    1 
ATOM   2452 C C     . LEU B 2 115 ? 134.727 127.797 103.872 1.00 21.02  ? 36  LEU A C     1 
ATOM   2453 O O     . LEU B 2 115 ? 135.511 127.294 103.062 1.00 21.02  ? 36  LEU A O     1 
ATOM   2454 C CB    . LEU B 2 115 ? 136.093 127.590 105.944 1.00 21.02  ? 36  LEU A CB    1 
ATOM   2455 C CG    . LEU B 2 115 ? 136.224 127.295 107.436 1.00 21.02  ? 36  LEU A CG    1 
ATOM   2456 C CD1   . LEU B 2 115 ? 137.677 127.377 107.860 1.00 21.02  ? 36  LEU A CD1   1 
ATOM   2457 C CD2   . LEU B 2 115 ? 135.375 128.255 108.244 1.00 21.02  ? 36  LEU A CD2   1 
ATOM   2458 N N     . LEU B 2 116 ? 133.877 128.769 103.553 1.00 19.59  ? 37  LEU A N     1 
ATOM   2459 C CA    . LEU B 2 116 ? 133.902 129.380 102.231 1.00 19.59  ? 37  LEU A CA    1 
ATOM   2460 C C     . LEU B 2 116 ? 135.042 130.385 102.184 1.00 19.59  ? 37  LEU A C     1 
ATOM   2461 O O     . LEU B 2 116 ? 135.375 130.994 103.199 1.00 19.59  ? 37  LEU A O     1 
ATOM   2462 C CB    . LEU B 2 116 ? 132.572 130.069 101.922 1.00 19.59  ? 37  LEU A CB    1 
ATOM   2463 C CG    . LEU B 2 116 ? 132.456 130.790 100.578 1.00 19.59  ? 37  LEU A CG    1 
ATOM   2464 C CD1   . LEU B 2 116 ? 132.815 129.877 99.417  1.00 19.59  ? 37  LEU A CD1   1 
ATOM   2465 C CD2   . LEU B 2 116 ? 131.051 131.338 100.406 1.00 19.59  ? 37  LEU A CD2   1 
ATOM   2466 N N     . LEU B 2 117 ? 135.665 130.534 101.017 1.00 25.10  ? 38  LEU A N     1 
ATOM   2467 C CA    . LEU B 2 117 ? 136.739 131.500 100.822 1.00 25.10  ? 38  LEU A CA    1 
ATOM   2468 C C     . LEU B 2 117 ? 136.317 132.481 99.738  1.00 25.10  ? 38  LEU A C     1 
ATOM   2469 O O     . LEU B 2 117 ? 135.965 132.070 98.627  1.00 25.10  ? 38  LEU A O     1 
ATOM   2470 C CB    . LEU B 2 117 ? 138.042 130.795 100.446 1.00 25.10  ? 38  LEU A CB    1 
ATOM   2471 C CG    . LEU B 2 117 ? 139.256 131.689 100.184 1.00 25.10  ? 38  LEU A CG    1 
ATOM   2472 C CD1   . LEU B 2 117 ? 139.555 132.565 101.386 1.00 25.10  ? 38  LEU A CD1   1 
ATOM   2473 C CD2   . LEU B 2 117 ? 140.467 130.848 99.823  1.00 25.10  ? 38  LEU A CD2   1 
ATOM   2474 N N     . LEU B 2 118 ? 136.354 133.772 100.061 1.00 25.04  ? 39  LEU A N     1 
ATOM   2475 C CA    . LEU B 2 118 ? 135.919 134.824 99.156  1.00 25.04  ? 39  LEU A CA    1 
ATOM   2476 C C     . LEU B 2 118 ? 136.948 135.945 99.160  1.00 25.04  ? 39  LEU A C     1 
ATOM   2477 O O     . LEU B 2 118 ? 137.944 135.903 99.886  1.00 25.04  ? 39  LEU A O     1 
ATOM   2478 C CB    . LEU B 2 118 ? 134.535 135.357 99.555  1.00 25.04  ? 39  LEU A CB    1 
ATOM   2479 C CG    . LEU B 2 118 ? 133.337 134.574 99.012  1.00 25.04  ? 39  LEU A CG    1 
ATOM   2480 C CD1   . LEU B 2 118 ? 132.043 135.101 99.599  1.00 25.04  ? 39  LEU A CD1   1 
ATOM   2481 C CD2   . LEU B 2 118 ? 133.288 134.638 97.494  1.00 25.04  ? 39  LEU A CD2   1 
ATOM   2482 N N     . GLY B 2 119 ? 136.706 136.946 98.332  1.00 33.69  ? 40  GLY A N     1 
ATOM   2483 C CA    . GLY B 2 119 ? 137.584 138.095 98.218  1.00 33.69  ? 40  GLY A CA    1 
ATOM   2484 C C     . GLY B 2 119 ? 137.830 138.453 96.766  1.00 33.69  ? 40  GLY A C     1 
ATOM   2485 O O     . GLY B 2 119 ? 137.494 137.712 95.842  1.00 33.69  ? 40  GLY A O     1 
ATOM   2486 N N     . ALA B 2 120 ? 138.433 139.622 96.562  1.00 42.75  ? 41  ALA A N     1 
ATOM   2487 C CA    . ALA B 2 120 ? 138.730 140.108 95.225  1.00 42.75  ? 41  ALA A CA    1 
ATOM   2488 C C     . ALA B 2 120 ? 140.063 139.542 94.741  1.00 42.75  ? 41  ALA A C     1 
ATOM   2489 O O     . ALA B 2 120 ? 140.767 138.828 95.460  1.00 42.75  ? 41  ALA A O     1 
ATOM   2490 C CB    . ALA B 2 120 ? 138.745 141.635 95.209  1.00 42.75  ? 41  ALA A CB    1 
ATOM   2491 N N     . GLY B 2 121 ? 140.415 139.864 93.499  1.00 47.51  ? 42  GLY A N     1 
ATOM   2492 C CA    . GLY B 2 121 ? 141.674 139.400 92.952  1.00 47.51  ? 42  GLY A CA    1 
ATOM   2493 C C     . GLY B 2 121 ? 142.861 140.087 93.598  1.00 47.51  ? 42  GLY A C     1 
ATOM   2494 O O     . GLY B 2 121 ? 142.785 141.230 94.050  1.00 47.51  ? 42  GLY A O     1 
ATOM   2495 N N     . GLU B 2 122 ? 143.984 139.369 93.638  1.00 51.10  ? 43  GLU A N     1 
ATOM   2496 C CA    . GLU B 2 122 ? 145.219 139.875 94.235  1.00 51.10  ? 43  GLU A CA    1 
ATOM   2497 C C     . GLU B 2 122 ? 144.979 140.316 95.679  1.00 51.10  ? 43  GLU A C     1 
ATOM   2498 O O     . GLU B 2 122 ? 145.562 141.287 96.165  1.00 51.10  ? 43  GLU A O     1 
ATOM   2499 C CB    . GLU B 2 122 ? 145.799 141.020 93.401  1.00 51.10  ? 43  GLU A CB    1 
ATOM   2500 C CG    . GLU B 2 122 ? 146.370 140.586 92.061  1.00 51.10  ? 43  GLU A CG    1 
ATOM   2501 C CD    . GLU B 2 122 ? 147.620 139.739 92.205  1.00 51.10  ? 43  GLU A CD    1 
ATOM   2502 O OE1   . GLU B 2 122 ? 148.431 140.023 93.111  1.00 51.10  ? 43  GLU A OE1   1 
ATOM   2503 O OE2   . GLU B 2 122 ? 147.792 138.791 91.410  1.00 51.10  ? 43  GLU A OE2   1 
ATOM   2504 N N     . SER B 2 123 ? 144.105 139.582 96.369  1.00 46.17  ? 44  SER A N     1 
ATOM   2505 C CA    . SER B 2 123 ? 143.741 139.887 97.744  1.00 46.17  ? 44  SER A CA    1 
ATOM   2506 C C     . SER B 2 123 ? 144.420 138.985 98.764  1.00 46.17  ? 44  SER A C     1 
ATOM   2507 O O     . SER B 2 123 ? 144.079 139.058 99.949  1.00 46.17  ? 44  SER A O     1 
ATOM   2508 C CB    . SER B 2 123 ? 142.219 139.783 97.924  1.00 46.17  ? 44  SER A CB    1 
ATOM   2509 O OG    . SER B 2 123 ? 141.550 140.813 97.220  1.00 46.17  ? 44  SER A OG    1 
ATOM   2510 N N     . GLY B 2 124 ? 145.364 138.146 98.346  1.00 44.27  ? 45  GLY A N     1 
ATOM   2511 C CA    . GLY B 2 124 ? 145.980 137.182 99.232  1.00 44.27  ? 45  GLY A CA    1 
ATOM   2512 C C     . GLY B 2 124 ? 145.284 135.840 99.283  1.00 44.27  ? 45  GLY A C     1 
ATOM   2513 O O     . GLY B 2 124 ? 145.709 134.972 100.056 1.00 44.27  ? 45  GLY A O     1 
ATOM   2514 N N     . LYS B 2 125 ? 144.226 135.646 98.494  1.00 35.27  ? 46  LYS A N     1 
ATOM   2515 C CA    . LYS B 2 125 ? 143.550 134.355 98.442  1.00 35.27  ? 46  LYS A CA    1 
ATOM   2516 C C     . LYS B 2 125 ? 144.545 133.242 98.130  1.00 35.27  ? 46  LYS A C     1 
ATOM   2517 O O     . LYS B 2 125 ? 144.625 132.235 98.844  1.00 35.27  ? 46  LYS A O     1 
ATOM   2518 C CB    . LYS B 2 125 ? 142.438 134.407 97.393  1.00 35.27  ? 46  LYS A CB    1 
ATOM   2519 C CG    . LYS B 2 125 ? 141.604 133.143 97.273  1.00 35.27  ? 46  LYS A CG    1 
ATOM   2520 C CD    . LYS B 2 125 ? 140.753 133.170 96.007  1.00 35.27  ? 46  LYS A CD    1 
ATOM   2521 C CE    . LYS B 2 125 ? 139.573 134.121 96.126  1.00 35.27  ? 46  LYS A CE    1 
ATOM   2522 N NZ    . LYS B 2 125 ? 138.539 133.621 97.070  1.00 35.27  ? 46  LYS A NZ    1 
ATOM   2523 N N     . SER B 2 126 ? 145.326 133.421 97.062  1.00 42.68  ? 47  SER A N     1 
ATOM   2524 C CA    . SER B 2 126 ? 146.374 132.458 96.743  1.00 42.68  ? 47  SER A CA    1 
ATOM   2525 C C     . SER B 2 126 ? 147.404 132.386 97.862  1.00 42.68  ? 47  SER A C     1 
ATOM   2526 O O     . SER B 2 126 ? 147.923 131.307 98.173  1.00 42.68  ? 47  SER A O     1 
ATOM   2527 C CB    . SER B 2 126 ? 147.045 132.831 95.422  1.00 42.68  ? 47  SER A CB    1 
ATOM   2528 O OG    . SER B 2 126 ? 146.126 132.763 94.346  1.00 42.68  ? 47  SER A OG    1 
ATOM   2529 N N     . THR B 2 127 ? 147.724 133.529 98.471  1.00 48.06  ? 48  THR A N     1 
ATOM   2530 C CA    . THR B 2 127 ? 148.659 133.529 99.590  1.00 48.06  ? 48  THR A CA    1 
ATOM   2531 C C     . THR B 2 127 ? 148.091 132.774 100.785 1.00 48.06  ? 48  THR A C     1 
ATOM   2532 O O     . THR B 2 127 ? 148.810 132.016 101.444 1.00 48.06  ? 48  THR A O     1 
ATOM   2533 C CB    . THR B 2 127 ? 149.005 134.965 99.982  1.00 48.06  ? 48  THR A CB    1 
ATOM   2534 O OG1   . THR B 2 127 ? 149.748 135.586 98.925  1.00 48.06  ? 48  THR A OG1   1 
ATOM   2535 C CG2   . THR B 2 127 ? 149.831 134.989 101.263 1.00 48.06  ? 48  THR A CG2   1 
ATOM   2536 N N     . ILE B 2 128 ? 146.803 132.964 101.078 1.00 41.98  ? 49  ILE A N     1 
ATOM   2537 C CA    . ILE B 2 128 ? 146.207 132.335 102.252 1.00 41.98  ? 49  ILE A CA    1 
ATOM   2538 C C     . ILE B 2 128 ? 146.074 130.830 102.059 1.00 41.98  ? 49  ILE A C     1 
ATOM   2539 O O     . ILE B 2 128 ? 146.337 130.053 102.984 1.00 41.98  ? 49  ILE A O     1 
ATOM   2540 C CB    . ILE B 2 128 ? 144.850 132.990 102.573 1.00 41.98  ? 49  ILE A CB    1 
ATOM   2541 C CG1   . ILE B 2 128 ? 145.050 134.345 103.262 1.00 41.98  ? 49  ILE A CG1   1 
ATOM   2542 C CG2   . ILE B 2 128 ? 143.996 132.072 103.444 1.00 41.98  ? 49  ILE A CG2   1 
ATOM   2543 C CD1   . ILE B 2 128 ? 145.758 134.280 104.608 1.00 41.98  ? 49  ILE A CD1   1 
ATOM   2544 N N     . VAL B 2 129 ? 145.660 130.386 100.868 1.00 39.90  ? 50  VAL A N     1 
ATOM   2545 C CA    . VAL B 2 129 ? 145.463 128.952 100.661 1.00 39.90  ? 50  VAL A CA    1 
ATOM   2546 C C     . VAL B 2 129 ? 146.765 128.194 100.877 1.00 39.90  ? 50  VAL A C     1 
ATOM   2547 O O     . VAL B 2 129 ? 146.760 127.073 101.401 1.00 39.90  ? 50  VAL A O     1 
ATOM   2548 C CB    . VAL B 2 129 ? 144.875 128.673 99.262  1.00 39.90  ? 50  VAL A CB    1 
ATOM   2549 C CG1   . VAL B 2 129 ? 143.480 129.268 99.143  1.00 39.90  ? 50  VAL A CG1   1 
ATOM   2550 C CG2   . VAL B 2 129 ? 145.784 129.212 98.173  1.00 39.90  ? 50  VAL A CG2   1 
ATOM   2551 N N     . LYS B 2 130 ? 147.896 128.779 100.483 1.00 45.91  ? 51  LYS A N     1 
ATOM   2552 C CA    . LYS B 2 130 ? 149.193 128.181 100.776 1.00 45.91  ? 51  LYS A CA    1 
ATOM   2553 C C     . LYS B 2 130 ? 149.574 128.351 102.240 1.00 45.91  ? 51  LYS A C     1 
ATOM   2554 O O     . LYS B 2 130 ? 150.116 127.425 102.853 1.00 45.91  ? 51  LYS A O     1 
ATOM   2555 C CB    . LYS B 2 130 ? 150.275 128.796 99.885  1.00 45.91  ? 51  LYS A CB    1 
ATOM   2556 C CG    . LYS B 2 130 ? 150.209 128.354 98.431  1.00 45.91  ? 51  LYS A CG    1 
ATOM   2557 C CD    . LYS B 2 130 ? 151.321 128.979 97.599  1.00 45.91  ? 51  LYS A CD    1 
ATOM   2558 C CE    . LYS B 2 130 ? 152.694 128.462 98.008  1.00 45.91  ? 51  LYS A CE    1 
ATOM   2559 N NZ    . LYS B 2 130 ? 153.774 128.977 97.121  1.00 45.91  ? 51  LYS A NZ    1 
ATOM   2560 N N     . GLN B 2 131 ? 149.300 129.525 102.813 1.00 47.29  ? 52  GLN A N     1 
ATOM   2561 C CA    . GLN B 2 131 ? 149.533 129.728 104.238 1.00 47.29  ? 52  GLN A CA    1 
ATOM   2562 C C     . GLN B 2 131 ? 148.669 128.797 105.075 1.00 47.29  ? 52  GLN A C     1 
ATOM   2563 O O     . GLN B 2 131 ? 149.111 128.312 106.122 1.00 47.29  ? 52  GLN A O     1 
ATOM   2564 C CB    . GLN B 2 131 ? 149.252 131.184 104.609 1.00 47.29  ? 52  GLN A CB    1 
ATOM   2565 C CG    . GLN B 2 131 ? 149.994 131.670 105.843 1.00 47.29  ? 52  GLN A CG    1 
ATOM   2566 C CD    . GLN B 2 131 ? 151.491 131.788 105.623 1.00 47.29  ? 52  GLN A CD    1 
ATOM   2567 O OE1   . GLN B 2 131 ? 152.287 131.337 106.447 1.00 47.29  ? 52  GLN A OE1   1 
ATOM   2568 N NE2   . GLN B 2 131 ? 151.882 132.405 104.513 1.00 47.29  ? 52  GLN A NE2   1 
ATOM   2569 N N     . MET B 2 132 ? 147.442 128.537 104.631 1.00 38.44  ? 53  MET A N     1 
ATOM   2570 C CA    . MET B 2 132 ? 146.533 127.692 105.385 1.00 38.44  ? 53  MET A CA    1 
ATOM   2571 C C     . MET B 2 132 ? 147.110 126.284 105.516 1.00 38.44  ? 53  MET A C     1 
ATOM   2572 O O     . MET B 2 132 ? 147.691 125.729 104.579 1.00 38.44  ? 53  MET A O     1 
ATOM   2573 C CB    . MET B 2 132 ? 145.166 127.640 104.701 1.00 38.44  ? 53  MET A CB    1 
ATOM   2574 C CG    . MET B 2 132 ? 144.107 126.883 105.481 1.00 38.44  ? 53  MET A CG    1 
ATOM   2575 S SD    . MET B 2 132 ? 143.739 127.685 107.054 1.00 38.44  ? 53  MET A SD    1 
ATOM   2576 C CE    . MET B 2 132 ? 142.830 129.122 106.492 1.00 38.44  ? 53  MET A CE    1 
ATOM   2577 N N     . LYS B 2 133 ? 146.943 125.707 106.701 1.00 37.27  ? 54  LYS A N     1 
ATOM   2578 C CA    . LYS B 2 133 ? 147.494 124.388 106.990 1.00 37.27  ? 54  LYS A CA    1 
ATOM   2579 C C     . LYS B 2 133 ? 146.911 123.345 106.041 1.00 37.27  ? 54  LYS A C     1 
ATOM   2580 O O     . LYS B 2 133 ? 147.485 123.058 104.990 1.00 37.27  ? 54  LYS A O     1 
ATOM   2581 C CB    . LYS B 2 133 ? 147.218 123.998 108.444 1.00 37.27  ? 54  LYS A CB    1 
ATOM   2582 C CG    . LYS B 2 133 ? 147.818 122.663 108.861 1.00 37.27  ? 54  LYS A CG    1 
ATOM   2583 C CD    . LYS B 2 133 ? 149.337 122.722 108.896 1.00 37.27  ? 54  LYS A CD    1 
ATOM   2584 C CE    . LYS B 2 133 ? 149.931 121.453 109.485 1.00 37.27  ? 54  LYS A CE    1 
ATOM   2585 N NZ    . LYS B 2 133 ? 149.575 120.246 108.688 1.00 37.27  ? 54  LYS A NZ    1 
ATOM   2586 N N     . GLY B 2 262 ? 137.760 125.215 88.303  1.00 18.81  ? 183 GLY A N     1 
ATOM   2587 C CA    . GLY B 2 262 ? 136.509 125.455 88.998  1.00 18.81  ? 183 GLY A CA    1 
ATOM   2588 C C     . GLY B 2 262 ? 136.699 125.641 90.490  1.00 18.81  ? 183 GLY A C     1 
ATOM   2589 O O     . GLY B 2 262 ? 137.566 126.398 90.925  1.00 18.81  ? 183 GLY A O     1 
ATOM   2590 N N     . ILE B 2 263 ? 135.879 124.947 91.279  1.00 18.44  ? 184 ILE A N     1 
ATOM   2591 C CA    . ILE B 2 263 ? 135.992 125.026 92.729  1.00 18.44  ? 184 ILE A CA    1 
ATOM   2592 C C     . ILE B 2 263 ? 137.213 124.242 93.186  1.00 18.44  ? 184 ILE A C     1 
ATOM   2593 O O     . ILE B 2 263 ? 137.473 123.128 92.712  1.00 18.44  ? 184 ILE A O     1 
ATOM   2594 C CB    . ILE B 2 263 ? 134.712 124.499 93.397  1.00 18.44  ? 184 ILE A CB    1 
ATOM   2595 C CG1   . ILE B 2 263 ? 134.749 124.765 94.902  1.00 18.44  ? 184 ILE A CG1   1 
ATOM   2596 C CG2   . ILE B 2 263 ? 134.540 123.009 93.132  1.00 18.44  ? 184 ILE A CG2   1 
ATOM   2597 C CD1   . ILE B 2 263 ? 133.380 124.842 95.531  1.00 18.44  ? 184 ILE A CD1   1 
ATOM   2598 N N     . VAL B 2 264 ? 137.972 124.821 94.112  1.00 22.09  ? 185 VAL A N     1 
ATOM   2599 C CA    . VAL B 2 264 ? 139.174 124.196 94.653  1.00 22.09  ? 185 VAL A CA    1 
ATOM   2600 C C     . VAL B 2 264 ? 138.935 123.920 96.130  1.00 22.09  ? 185 VAL A C     1 
ATOM   2601 O O     . VAL B 2 264 ? 138.676 124.844 96.910  1.00 22.09  ? 185 VAL A O     1 
ATOM   2602 C CB    . VAL B 2 264 ? 140.413 125.080 94.449  1.00 22.09  ? 185 VAL A CB    1 
ATOM   2603 C CG1   . VAL B 2 264 ? 141.654 124.388 94.992  1.00 22.09  ? 185 VAL A CG1   1 
ATOM   2604 C CG2   . VAL B 2 264 ? 140.586 125.417 92.977  1.00 22.09  ? 185 VAL A CG2   1 
ATOM   2605 N N     . GLU B 2 265 ? 139.027 122.653 96.518  1.00 21.74  ? 186 GLU A N     1 
ATOM   2606 C CA    . GLU B 2 265 ? 138.806 122.237 97.895  1.00 21.74  ? 186 GLU A CA    1 
ATOM   2607 C C     . GLU B 2 265 ? 140.143 121.934 98.556  1.00 21.74  ? 186 GLU A C     1 
ATOM   2608 O O     . GLU B 2 265 ? 140.964 121.199 97.998  1.00 21.74  ? 186 GLU A O     1 
ATOM   2609 C CB    . GLU B 2 265 ? 137.900 121.007 97.952  1.00 21.74  ? 186 GLU A CB    1 
ATOM   2610 C CG    . GLU B 2 265 ? 136.620 121.142 97.146  1.00 21.74  ? 186 GLU A CG    1 
ATOM   2611 C CD    . GLU B 2 265 ? 135.597 120.082 97.502  1.00 21.74  ? 186 GLU A CD    1 
ATOM   2612 O OE1   . GLU B 2 265 ? 136.003 118.942 97.809  1.00 21.74  ? 186 GLU A OE1   1 
ATOM   2613 O OE2   . GLU B 2 265 ? 134.387 120.387 97.479  1.00 21.74  ? 186 GLU A OE2   1 
ATOM   2614 N N     . THR B 2 266 ? 140.358 122.501 99.741  1.00 25.12  ? 187 THR A N     1 
ATOM   2615 C CA    . THR B 2 266 ? 141.556 122.254 100.533 1.00 25.12  ? 187 THR A CA    1 
ATOM   2616 C C     . THR B 2 266 ? 141.134 121.630 101.854 1.00 25.12  ? 187 THR A C     1 
ATOM   2617 O O     . THR B 2 266 ? 140.407 122.253 102.633 1.00 25.12  ? 187 THR A O     1 
ATOM   2618 C CB    . THR B 2 266 ? 142.339 123.546 100.774 1.00 25.12  ? 187 THR A CB    1 
ATOM   2619 O OG1   . THR B 2 266 ? 142.860 124.034 99.531  1.00 25.12  ? 187 THR A OG1   1 
ATOM   2620 C CG2   . THR B 2 266 ? 143.491 123.303 101.739 1.00 25.12  ? 187 THR A CG2   1 
ATOM   2621 N N     . HIS B 2 267 ? 141.581 120.403 102.099 1.00 25.92  ? 188 HIS A N     1 
ATOM   2622 C CA    . HIS B 2 267 ? 141.266 119.678 103.321 1.00 25.92  ? 188 HIS A CA    1 
ATOM   2623 C C     . HIS B 2 267 ? 142.483 119.705 104.232 1.00 25.92  ? 188 HIS A C     1 
ATOM   2624 O O     . HIS B 2 267 ? 143.575 119.297 103.822 1.00 25.92  ? 188 HIS A O     1 
ATOM   2625 C CB    . HIS B 2 267 ? 140.868 118.232 103.017 1.00 25.92  ? 188 HIS A CB    1 
ATOM   2626 C CG    . HIS B 2 267 ? 139.771 118.103 102.007 1.00 25.92  ? 188 HIS A CG    1 
ATOM   2627 N ND1   . HIS B 2 267 ? 139.889 118.567 100.714 1.00 25.92  ? 188 HIS A ND1   1 
ATOM   2628 C CD2   . HIS B 2 267 ? 138.537 117.553 102.096 1.00 25.92  ? 188 HIS A CD2   1 
ATOM   2629 C CE1   . HIS B 2 267 ? 138.774 118.313 100.053 1.00 25.92  ? 188 HIS A CE1   1 
ATOM   2630 N NE2   . HIS B 2 267 ? 137.938 117.698 100.869 1.00 25.92  ? 188 HIS A NE2   1 
ATOM   2631 N N     . PHE B 2 268 ? 142.299 120.184 105.460 1.00 29.15  ? 189 PHE A N     1 
ATOM   2632 C CA    . PHE B 2 268 ? 143.409 120.255 106.402 1.00 29.15  ? 189 PHE A CA    1 
ATOM   2633 C C     . PHE B 2 268 ? 142.918 120.061 107.828 1.00 29.15  ? 189 PHE A C     1 
ATOM   2634 O O     . PHE B 2 268 ? 141.807 120.463 108.170 1.00 29.15  ? 189 PHE A O     1 
ATOM   2635 C CB    . PHE B 2 268 ? 144.164 121.588 106.280 1.00 29.15  ? 189 PHE A CB    1 
ATOM   2636 C CG    . PHE B 2 268 ? 143.337 122.794 106.620 1.00 29.15  ? 189 PHE A CG    1 
ATOM   2637 C CD1   . PHE B 2 268 ? 142.340 123.229 105.763 1.00 29.15  ? 189 PHE A CD1   1 
ATOM   2638 C CD2   . PHE B 2 268 ? 143.585 123.520 107.771 1.00 29.15  ? 189 PHE A CD2   1 
ATOM   2639 C CE1   . PHE B 2 268 ? 141.589 124.348 106.060 1.00 29.15  ? 189 PHE A CE1   1 
ATOM   2640 C CE2   . PHE B 2 268 ? 142.832 124.636 108.078 1.00 29.15  ? 189 PHE A CE2   1 
ATOM   2641 C CZ    . PHE B 2 268 ? 141.834 125.050 107.220 1.00 29.15  ? 189 PHE A CZ    1 
ATOM   2642 N N     . THR B 2 269 ? 143.761 119.458 108.660 1.00 30.25  ? 190 THR A N     1 
ATOM   2643 C CA    . THR B 2 269 ? 143.425 119.157 110.046 1.00 30.25  ? 190 THR A CA    1 
ATOM   2644 C C     . THR B 2 269 ? 144.222 120.076 110.961 1.00 30.25  ? 190 THR A C     1 
ATOM   2645 O O     . THR B 2 269 ? 145.431 120.249 110.773 1.00 30.25  ? 190 THR A O     1 
ATOM   2646 C CB    . THR B 2 269 ? 143.713 117.692 110.375 1.00 30.25  ? 190 THR A CB    1 
ATOM   2647 O OG1   . THR B 2 269 ? 142.915 116.845 109.540 1.00 30.25  ? 190 THR A OG1   1 
ATOM   2648 C CG2   . THR B 2 269 ? 143.397 117.399 111.835 1.00 30.25  ? 190 THR A CG2   1 
ATOM   2649 N N     . PHE B 2 270 ? 143.544 120.664 111.944 1.00 31.69  ? 191 PHE A N     1 
ATOM   2650 C CA    . PHE B 2 270 ? 144.170 121.535 112.931 1.00 31.69  ? 191 PHE A CA    1 
ATOM   2651 C C     . PHE B 2 270 ? 143.520 121.288 114.283 1.00 31.69  ? 191 PHE A C     1 
ATOM   2652 O O     . PHE B 2 270 ? 142.315 121.509 114.443 1.00 31.69  ? 191 PHE A O     1 
ATOM   2653 C CB    . PHE B 2 270 ? 144.035 123.007 112.532 1.00 31.69  ? 191 PHE A CB    1 
ATOM   2654 C CG    . PHE B 2 270 ? 145.030 123.911 113.202 1.00 31.69  ? 191 PHE A CG    1 
ATOM   2655 C CD1   . PHE B 2 270 ? 146.371 123.861 112.862 1.00 31.69  ? 191 PHE A CD1   1 
ATOM   2656 C CD2   . PHE B 2 270 ? 144.622 124.812 114.169 1.00 31.69  ? 191 PHE A CD2   1 
ATOM   2657 C CE1   . PHE B 2 270 ? 147.286 124.693 113.478 1.00 31.69  ? 191 PHE A CE1   1 
ATOM   2658 C CE2   . PHE B 2 270 ? 145.533 125.645 114.788 1.00 31.69  ? 191 PHE A CE2   1 
ATOM   2659 C CZ    . PHE B 2 270 ? 146.867 125.585 114.441 1.00 31.69  ? 191 PHE A CZ    1 
ATOM   2660 N N     . LYS B 2 271 ? 144.316 120.826 115.249 1.00 31.39  ? 192 LYS A N     1 
ATOM   2661 C CA    . LYS B 2 271 ? 143.857 120.635 116.625 1.00 31.39  ? 192 LYS A CA    1 
ATOM   2662 C C     . LYS B 2 271 ? 142.571 119.813 116.676 1.00 31.39  ? 192 LYS A C     1 
ATOM   2663 O O     . LYS B 2 271 ? 141.608 120.166 117.360 1.00 31.39  ? 192 LYS A O     1 
ATOM   2664 C CB    . LYS B 2 271 ? 143.666 121.982 117.326 1.00 31.39  ? 192 LYS A CB    1 
ATOM   2665 C CG    . LYS B 2 271 ? 144.871 122.921 117.260 1.00 31.39  ? 192 LYS A CG    1 
ATOM   2666 C CD    . LYS B 2 271 ? 146.149 122.304 117.822 1.00 31.39  ? 192 LYS A CD    1 
ATOM   2667 C CE    . LYS B 2 271 ? 147.381 122.867 117.134 1.00 31.39  ? 192 LYS A CE    1 
ATOM   2668 N NZ    . LYS B 2 271 ? 147.747 122.089 115.919 1.00 31.39  ? 192 LYS A NZ    1 
ATOM   2669 N N     . ASP B 2 272 ? 142.557 118.704 115.942 1.00 30.46  ? 193 ASP A N     1 
ATOM   2670 C CA    . ASP B 2 272 ? 141.480 117.718 115.907 1.00 30.46  ? 193 ASP A CA    1 
ATOM   2671 C C     . ASP B 2 272 ? 140.286 118.196 115.088 1.00 30.46  ? 193 ASP A C     1 
ATOM   2672 O O     . ASP B 2 272 ? 139.303 117.454 114.977 1.00 30.46  ? 193 ASP A O     1 
ATOM   2673 C CB    . ASP B 2 272 ? 140.990 117.336 117.313 1.00 30.46  ? 193 ASP A CB    1 
ATOM   2674 C CG    . ASP B 2 272 ? 140.271 116.002 117.339 1.00 30.46  ? 193 ASP A CG    1 
ATOM   2675 O OD1   . ASP B 2 272 ? 140.152 115.364 116.272 1.00 30.46  ? 193 ASP A OD1   1 
ATOM   2676 O OD2   . ASP B 2 272 ? 139.821 115.590 118.430 1.00 30.46  ? 193 ASP A OD2   1 
ATOM   2677 N N     . LEU B 2 273 ? 140.328 119.394 114.513 1.00 26.28  ? 194 LEU A N     1 
ATOM   2678 C CA    . LEU B 2 273 ? 139.251 119.901 113.675 1.00 26.28  ? 194 LEU A CA    1 
ATOM   2679 C C     . LEU B 2 273 ? 139.640 119.741 112.212 1.00 26.28  ? 194 LEU A C     1 
ATOM   2680 O O     . LEU B 2 273 ? 140.697 120.221 111.793 1.00 26.28  ? 194 LEU A O     1 
ATOM   2681 C CB    . LEU B 2 273 ? 138.966 121.372 113.982 1.00 26.28  ? 194 LEU A CB    1 
ATOM   2682 C CG    . LEU B 2 273 ? 137.830 121.697 114.953 1.00 26.28  ? 194 LEU A CG    1 
ATOM   2683 C CD1   . LEU B 2 273 ? 137.703 123.203 115.111 1.00 26.28  ? 194 LEU A CD1   1 
ATOM   2684 C CD2   . LEU B 2 273 ? 136.515 121.099 114.483 1.00 26.28  ? 194 LEU A CD2   1 
ATOM   2685 N N     . HIS B 2 274 ? 138.786 119.075 111.441 1.00 26.30  ? 195 HIS A N     1 
ATOM   2686 C CA    . HIS B 2 274 ? 139.035 118.841 110.024 1.00 26.30  ? 195 HIS A CA    1 
ATOM   2687 C C     . HIS B 2 274 ? 138.272 119.887 109.222 1.00 26.30  ? 195 HIS A C     1 
ATOM   2688 O O     . HIS B 2 274 ? 137.039 119.939 109.275 1.00 26.30  ? 195 HIS A O     1 
ATOM   2689 C CB    . HIS B 2 274 ? 138.613 117.429 109.619 1.00 26.30  ? 195 HIS A CB    1 
ATOM   2690 C CG    . HIS B 2 274 ? 138.666 117.182 108.143 1.00 26.30  ? 195 HIS A CG    1 
ATOM   2691 N ND1   . HIS B 2 274 ? 137.535 117.069 107.364 1.00 26.30  ? 195 HIS A ND1   1 
ATOM   2692 C CD2   . HIS B 2 274 ? 139.717 117.016 107.306 1.00 26.30  ? 195 HIS A CD2   1 
ATOM   2693 C CE1   . HIS B 2 274 ? 137.887 116.851 106.110 1.00 26.30  ? 195 HIS A CE1   1 
ATOM   2694 N NE2   . HIS B 2 274 ? 139.205 116.814 106.047 1.00 26.30  ? 195 HIS A NE2   1 
ATOM   2695 N N     . PHE B 2 275 ? 139.006 120.712 108.482 1.00 25.01  ? 196 PHE A N     1 
ATOM   2696 C CA    . PHE B 2 275 ? 138.465 121.847 107.754 1.00 25.01  ? 196 PHE A CA    1 
ATOM   2697 C C     . PHE B 2 275 ? 138.463 121.553 106.263 1.00 25.01  ? 196 PHE A C     1 
ATOM   2698 O O     . PHE B 2 275 ? 139.474 121.097 105.711 1.00 25.01  ? 196 PHE A O     1 
ATOM   2699 C CB    . PHE B 2 275 ? 139.297 123.104 108.012 1.00 25.01  ? 196 PHE A CB    1 
ATOM   2700 C CG    . PHE B 2 275 ? 139.332 123.534 109.444 1.00 25.01  ? 196 PHE A CG    1 
ATOM   2701 C CD1   . PHE B 2 275 ? 140.323 123.077 110.293 1.00 25.01  ? 196 PHE A CD1   1 
ATOM   2702 C CD2   . PHE B 2 275 ? 138.388 124.414 109.936 1.00 25.01  ? 196 PHE A CD2   1 
ATOM   2703 C CE1   . PHE B 2 275 ? 140.363 123.480 111.609 1.00 25.01  ? 196 PHE A CE1   1 
ATOM   2704 C CE2   . PHE B 2 275 ? 138.422 124.817 111.248 1.00 25.01  ? 196 PHE A CE2   1 
ATOM   2705 C CZ    . PHE B 2 275 ? 139.411 124.352 112.088 1.00 25.01  ? 196 PHE A CZ    1 
ATOM   2706 N N     . LYS B 2 276 ? 137.330 121.825 105.623 1.00 24.30  ? 197 LYS A N     1 
ATOM   2707 C CA    . LYS B 2 276 ? 137.207 121.863 104.172 1.00 24.30  ? 197 LYS A CA    1 
ATOM   2708 C C     . LYS B 2 276 ? 137.048 123.324 103.771 1.00 24.30  ? 197 LYS A C     1 
ATOM   2709 O O     . LYS B 2 276 ? 135.996 123.926 104.012 1.00 24.30  ? 197 LYS A O     1 
ATOM   2710 C CB    . LYS B 2 276 ? 136.011 121.046 103.689 1.00 24.30  ? 197 LYS A CB    1 
ATOM   2711 C CG    . LYS B 2 276 ? 136.140 119.545 103.840 1.00 24.30  ? 197 LYS A CG    1 
ATOM   2712 C CD    . LYS B 2 276 ? 135.286 118.823 102.801 1.00 24.30  ? 197 LYS A CD    1 
ATOM   2713 C CE    . LYS B 2 276 ? 134.312 117.846 103.434 1.00 24.30  ? 197 LYS A CE    1 
ATOM   2714 N NZ    . LYS B 2 276 ? 133.147 117.569 102.550 1.00 24.30  ? 197 LYS A NZ    1 
ATOM   2715 N N     . MET B 2 277 ? 138.086 123.894 103.167 1.00 25.51  ? 198 MET A N     1 
ATOM   2716 C CA    . MET B 2 277 ? 138.057 125.269 102.690 1.00 25.51  ? 198 MET A CA    1 
ATOM   2717 C C     . MET B 2 277 ? 137.777 125.256 101.193 1.00 25.51  ? 198 MET A C     1 
ATOM   2718 O O     . MET B 2 277 ? 138.535 124.659 100.421 1.00 25.51  ? 198 MET A O     1 
ATOM   2719 C CB    . MET B 2 277 ? 139.377 125.976 102.994 1.00 25.51  ? 198 MET A CB    1 
ATOM   2720 C CG    . MET B 2 277 ? 139.358 127.467 102.715 1.00 25.51  ? 198 MET A CG    1 
ATOM   2721 S SD    . MET B 2 277 ? 140.764 128.320 103.449 1.00 25.51  ? 198 MET A SD    1 
ATOM   2722 C CE    . MET B 2 277 ? 142.110 127.652 102.479 1.00 25.51  ? 198 MET A CE    1 
ATOM   2723 N N     . PHE B 2 278 ? 136.692 125.906 100.791 1.00 20.34  ? 199 PHE A N     1 
ATOM   2724 C CA    . PHE B 2 278 ? 136.243 125.908 99.405  1.00 20.34  ? 199 PHE A CA    1 
ATOM   2725 C C     . PHE B 2 278 ? 136.531 127.266 98.782  1.00 20.34  ? 199 PHE A C     1 
ATOM   2726 O O     . PHE B 2 278 ? 135.977 128.281 99.216  1.00 20.34  ? 199 PHE A O     1 
ATOM   2727 C CB    . PHE B 2 278 ? 134.753 125.586 99.325  1.00 20.34  ? 199 PHE A CB    1 
ATOM   2728 C CG    . PHE B 2 278 ? 134.338 124.455 100.210 1.00 20.34  ? 199 PHE A CG    1 
ATOM   2729 C CD1   . PHE B 2 278 ? 134.722 123.158 99.918  1.00 20.34  ? 199 PHE A CD1   1 
ATOM   2730 C CD2   . PHE B 2 278 ? 133.582 124.686 101.343 1.00 20.34  ? 199 PHE A CD2   1 
ATOM   2731 C CE1   . PHE B 2 278 ? 134.347 122.114 100.732 1.00 20.34  ? 199 PHE A CE1   1 
ATOM   2732 C CE2   . PHE B 2 278 ? 133.208 123.645 102.162 1.00 20.34  ? 199 PHE A CE2   1 
ATOM   2733 C CZ    . PHE B 2 278 ? 133.590 122.357 101.858 1.00 20.34  ? 199 PHE A CZ    1 
ATOM   2734 N N     . ASP B 2 279 ? 137.386 127.277 97.762  1.00 23.72  ? 200 ASP A N     1 
ATOM   2735 C CA    . ASP B 2 279 ? 137.743 128.482 97.029  1.00 23.72  ? 200 ASP A CA    1 
ATOM   2736 C C     . ASP B 2 279 ? 136.988 128.459 95.706  1.00 23.72  ? 200 ASP A C     1 
ATOM   2737 O O     . ASP B 2 279 ? 137.086 127.487 94.947  1.00 23.72  ? 200 ASP A O     1 
ATOM   2738 C CB    . ASP B 2 279 ? 139.257 128.536 96.811  1.00 23.72  ? 200 ASP A CB    1 
ATOM   2739 C CG    . ASP B 2 279 ? 139.694 129.607 95.814  1.00 23.72  ? 200 ASP A CG    1 
ATOM   2740 O OD1   . ASP B 2 279 ? 138.882 130.082 94.995  1.00 23.72  ? 200 ASP A OD1   1 
ATOM   2741 O OD2   . ASP B 2 279 ? 140.887 129.970 95.853  1.00 23.72  ? 200 ASP A OD2   1 
ATOM   2742 N N     . VAL B 2 280 ? 136.239 129.526 95.435  1.00 21.88  ? 201 VAL A N     1 
ATOM   2743 C CA    . VAL B 2 280 ? 135.441 129.627 94.219  1.00 21.88  ? 201 VAL A CA    1 
ATOM   2744 C C     . VAL B 2 280 ? 135.904 130.823 93.398  1.00 21.88  ? 201 VAL A C     1 
ATOM   2745 O O     . VAL B 2 280 ? 135.116 131.429 92.664  1.00 21.88  ? 201 VAL A O     1 
ATOM   2746 C CB    . VAL B 2 280 ? 133.940 129.735 94.545  1.00 21.88  ? 201 VAL A CB    1 
ATOM   2747 C CG1   . VAL B 2 280 ? 133.467 128.491 95.272  1.00 21.88  ? 201 VAL A CG1   1 
ATOM   2748 C CG2   . VAL B 2 280 ? 133.657 130.984 95.373  1.00 21.88  ? 201 VAL A CG2   1 
ATOM   2749 N N     . GLY B 2 281 ? 137.188 131.172 93.516  1.00 25.19  ? 202 GLY A N     1 
ATOM   2750 C CA    . GLY B 2 281 ? 137.729 132.266 92.731  1.00 25.19  ? 202 GLY A CA    1 
ATOM   2751 C C     . GLY B 2 281 ? 137.897 131.953 91.262  1.00 25.19  ? 202 GLY A C     1 
ATOM   2752 O O     . GLY B 2 281 ? 137.929 132.877 90.443  1.00 25.19  ? 202 GLY A O     1 
ATOM   2753 N N     . GLY B 2 282 ? 138.000 130.671 90.908  1.00 27.83  ? 203 GLY A N     1 
ATOM   2754 C CA    . GLY B 2 282 ? 138.123 130.291 89.512  1.00 27.83  ? 203 GLY A CA    1 
ATOM   2755 C C     . GLY B 2 282 ? 136.878 130.555 88.696  1.00 27.83  ? 203 GLY A C     1 
ATOM   2756 O O     . GLY B 2 282 ? 136.977 130.747 87.480  1.00 27.83  ? 203 GLY A O     1 
ATOM   2757 N N     . GLN B 2 283 ? 135.710 130.569 89.333  1.00 23.62  ? 204 GLN A N     1 
ATOM   2758 C CA    . GLN B 2 283 ? 134.480 130.883 88.621  1.00 23.62  ? 204 GLN A CA    1 
ATOM   2759 C C     . GLN B 2 283 ? 134.546 132.304 88.079  1.00 23.62  ? 204 GLN A C     1 
ATOM   2760 O O     . GLN B 2 283 ? 134.490 133.275 88.838  1.00 23.62  ? 204 GLN A O     1 
ATOM   2761 C CB    . GLN B 2 283 ? 133.278 130.723 89.551  1.00 23.62  ? 204 GLN A CB    1 
ATOM   2762 C CG    . GLN B 2 283 ? 132.838 129.279 89.754  1.00 23.62  ? 204 GLN A CG    1 
ATOM   2763 C CD    . GLN B 2 283 ? 132.208 128.665 88.516  1.00 23.62  ? 204 GLN A CD    1 
ATOM   2764 O OE1   . GLN B 2 283 ? 132.473 127.510 88.185  1.00 23.62  ? 204 GLN A OE1   1 
ATOM   2765 N NE2   . GLN B 2 283 ? 131.365 129.429 87.831  1.00 23.62  ? 204 GLN A NE2   1 
ATOM   2766 N N     . ARG B 2 284 ? 134.657 132.423 86.756  1.00 30.68  ? 205 ARG A N     1 
ATOM   2767 C CA    . ARG B 2 284 ? 134.834 133.714 86.110  1.00 30.68  ? 205 ARG A CA    1 
ATOM   2768 C C     . ARG B 2 284 ? 133.533 134.475 85.915  1.00 30.68  ? 205 ARG A C     1 
ATOM   2769 O O     . ARG B 2 284 ? 133.574 135.634 85.487  1.00 30.68  ? 205 ARG A O     1 
ATOM   2770 C CB    . ARG B 2 284 ? 135.524 133.532 84.750  1.00 30.68  ? 205 ARG A CB    1 
ATOM   2771 C CG    . ARG B 2 284 ? 136.984 133.120 84.860  1.00 30.68  ? 205 ARG A CG    1 
ATOM   2772 C CD    . ARG B 2 284 ? 137.572 132.756 83.507  1.00 30.68  ? 205 ARG A CD    1 
ATOM   2773 N NE    . ARG B 2 284 ? 138.979 132.385 83.612  1.00 30.68  ? 205 ARG A NE    1 
ATOM   2774 C CZ    . ARG B 2 284 ? 139.750 132.065 82.582  1.00 30.68  ? 205 ARG A CZ    1 
ATOM   2775 N NH1   . ARG B 2 284 ? 139.284 132.055 81.344  1.00 30.68  ? 205 ARG A NH1   1 
ATOM   2776 N NH2   . ARG B 2 284 ? 141.023 131.747 82.800  1.00 30.68  ? 205 ARG A NH2   1 
ATOM   2777 N N     . SER B 2 285 ? 132.389 133.864 86.210  1.00 28.34  ? 206 SER A N     1 
ATOM   2778 C CA    . SER B 2 285 ? 131.109 134.556 86.139  1.00 28.34  ? 206 SER A CA    1 
ATOM   2779 C C     . SER B 2 285 ? 130.722 135.037 87.532  1.00 28.34  ? 206 SER A C     1 
ATOM   2780 O O     . SER B 2 285 ? 130.590 134.230 88.457  1.00 28.34  ? 206 SER A O     1 
ATOM   2781 C CB    . SER B 2 285 ? 130.035 133.632 85.572  1.00 28.34  ? 206 SER A CB    1 
ATOM   2782 O OG    . SER B 2 285 ? 129.811 132.528 86.432  1.00 28.34  ? 206 SER A OG    1 
ATOM   2783 N N     . GLU B 2 286 ? 130.554 136.348 87.688  1.00 35.65  ? 207 GLU A N     1 
ATOM   2784 C CA    . GLU B 2 286 ? 130.117 136.925 88.959  1.00 35.65  ? 207 GLU A CA    1 
ATOM   2785 C C     . GLU B 2 286 ? 128.600 136.985 89.060  1.00 35.65  ? 207 GLU A C     1 
ATOM   2786 O O     . GLU B 2 286 ? 128.026 138.044 89.330  1.00 35.65  ? 207 GLU A O     1 
ATOM   2787 C CB    . GLU B 2 286 ? 130.731 138.312 89.129  1.00 35.65  ? 207 GLU A CB    1 
ATOM   2788 C CG    . GLU B 2 286 ? 132.124 138.301 89.750  1.00 35.65  ? 207 GLU A CG    1 
ATOM   2789 C CD    . GLU B 2 286 ? 133.231 138.130 88.724  1.00 35.65  ? 207 GLU A CD    1 
ATOM   2790 O OE1   . GLU B 2 286 ? 133.004 138.440 87.535  1.00 35.65  ? 207 GLU A OE1   1 
ATOM   2791 O OE2   . GLU B 2 286 ? 134.331 137.681 89.108  1.00 35.65  ? 207 GLU A OE2   1 
ATOM   2792 N N     . ARG B 2 287 ? 127.923 135.857 88.851  1.00 28.06  ? 208 ARG A N     1 
ATOM   2793 C CA    . ARG B 2 287 ? 126.468 135.816 88.809  1.00 28.06  ? 208 ARG A CA    1 
ATOM   2794 C C     . ARG B 2 287 ? 125.854 135.153 90.038  1.00 28.06  ? 208 ARG A C     1 
ATOM   2795 O O     . ARG B 2 287 ? 124.644 134.907 90.050  1.00 28.06  ? 208 ARG A O     1 
ATOM   2796 C CB    . ARG B 2 287 ? 126.003 135.096 87.539  1.00 28.06  ? 208 ARG A CB    1 
ATOM   2797 C CG    . ARG B 2 287 ? 124.561 135.382 87.123  1.00 28.06  ? 208 ARG A CG    1 
ATOM   2798 C CD    . ARG B 2 287 ? 124.255 136.873 87.050  1.00 28.06  ? 208 ARG A CD    1 
ATOM   2799 N NE    . ARG B 2 287 ? 122.961 137.144 86.435  1.00 28.06  ? 208 ARG A NE    1 
ATOM   2800 C CZ    . ARG B 2 287 ? 121.790 136.892 87.005  1.00 28.06  ? 208 ARG A CZ    1 
ATOM   2801 N NH1   . ARG B 2 287 ? 121.709 136.347 88.209  1.00 28.06  ? 208 ARG A NH1   1 
ATOM   2802 N NH2   . ARG B 2 287 ? 120.673 137.196 86.353  1.00 28.06  ? 208 ARG A NH2   1 
ATOM   2803 N N     . LYS B 2 288 ? 126.657 134.858 91.063  1.00 23.90  ? 209 LYS A N     1 
ATOM   2804 C CA    . LYS B 2 288 ? 126.166 134.383 92.355  1.00 23.90  ? 209 LYS A CA    1 
ATOM   2805 C C     . LYS B 2 288 ? 125.061 133.338 92.238  1.00 23.90  ? 209 LYS A C     1 
ATOM   2806 O O     . LYS B 2 288 ? 124.172 133.275 93.092  1.00 23.90  ? 209 LYS A O     1 
ATOM   2807 C CB    . LYS B 2 288 ? 125.684 135.564 93.215  1.00 23.90  ? 209 LYS A CB    1 
ATOM   2808 C CG    . LYS B 2 288 ? 124.564 136.450 92.639  1.00 23.90  ? 209 LYS A CG    1 
ATOM   2809 C CD    . LYS B 2 288 ? 123.170 135.924 92.940  1.00 23.90  ? 209 LYS A CD    1 
ATOM   2810 C CE    . LYS B 2 288 ? 122.102 136.925 92.531  1.00 23.90  ? 209 LYS A CE    1 
ATOM   2811 N NZ    . LYS B 2 288 ? 120.730 136.421 92.815  1.00 23.90  ? 209 LYS A NZ    1 
ATOM   2812 N N     . LYS B 2 289 ? 125.121 132.491 91.213  1.00 21.12  ? 210 LYS A N     1 
ATOM   2813 C CA    . LYS B 2 289 ? 124.139 131.432 91.030  1.00 21.12  ? 210 LYS A CA    1 
ATOM   2814 C C     . LYS B 2 289 ? 124.442 130.198 91.871  1.00 21.12  ? 210 LYS A C     1 
ATOM   2815 O O     . LYS B 2 289 ? 123.725 129.199 91.763  1.00 21.12  ? 210 LYS A O     1 
ATOM   2816 C CB    . LYS B 2 289 ? 124.055 131.034 89.555  1.00 21.12  ? 210 LYS A CB    1 
ATOM   2817 C CG    . LYS B 2 289 ? 123.660 132.158 88.608  1.00 21.12  ? 210 LYS A CG    1 
ATOM   2818 C CD    . LYS B 2 289 ? 122.276 132.724 88.905  1.00 21.12  ? 210 LYS A CD    1 
ATOM   2819 C CE    . LYS B 2 289 ? 121.175 131.806 88.411  1.00 21.12  ? 210 LYS A CE    1 
ATOM   2820 N NZ    . LYS B 2 289 ? 119.867 132.132 89.039  1.00 21.12  ? 210 LYS A NZ    1 
ATOM   2821 N N     . TRP B 2 290 ? 125.487 130.244 92.698  1.00 20.38  ? 211 TRP A N     1 
ATOM   2822 C CA    . TRP B 2 290 ? 125.873 129.101 93.510  1.00 20.38  ? 211 TRP A CA    1 
ATOM   2823 C C     . TRP B 2 290 ? 126.218 129.465 94.945  1.00 20.38  ? 211 TRP A C     1 
ATOM   2824 O O     . TRP B 2 290 ? 126.533 128.563 95.727  1.00 20.38  ? 211 TRP A O     1 
ATOM   2825 C CB    . TRP B 2 290 ? 127.074 128.389 92.878  1.00 20.38  ? 211 TRP A CB    1 
ATOM   2826 C CG    . TRP B 2 290 ? 128.186 129.326 92.575  1.00 20.38  ? 211 TRP A CG    1 
ATOM   2827 C CD1   . TRP B 2 290 ? 129.268 129.601 93.357  1.00 20.38  ? 211 TRP A CD1   1 
ATOM   2828 C CD2   . TRP B 2 290 ? 128.317 130.135 91.408  1.00 20.38  ? 211 TRP A CD2   1 
ATOM   2829 N NE1   . TRP B 2 290 ? 130.071 130.529 92.740  1.00 20.38  ? 211 TRP A NE1   1 
ATOM   2830 C CE2   . TRP B 2 290 ? 129.507 130.872 91.541  1.00 20.38  ? 211 TRP A CE2   1 
ATOM   2831 C CE3   . TRP B 2 290 ? 127.542 130.305 90.259  1.00 20.38  ? 211 TRP A CE3   1 
ATOM   2832 C CZ2   . TRP B 2 290 ? 129.941 131.764 90.567  1.00 20.38  ? 211 TRP A CZ2   1 
ATOM   2833 C CZ3   . TRP B 2 290 ? 127.973 131.188 89.296  1.00 20.38  ? 211 TRP A CZ3   1 
ATOM   2834 C CH2   . TRP B 2 290 ? 129.160 131.907 89.454  1.00 20.38  ? 211 TRP A CH2   1 
ATOM   2835 N N     . ILE B 2 291 ? 126.180 130.745 95.319  1.00 20.08  ? 212 ILE A N     1 
ATOM   2836 C CA    . ILE B 2 291 ? 126.496 131.113 96.695  1.00 20.08  ? 212 ILE A CA    1 
ATOM   2837 C C     . ILE B 2 291 ? 125.496 130.490 97.655  1.00 20.08  ? 212 ILE A C     1 
ATOM   2838 O O     . ILE B 2 291 ? 125.846 130.145 98.790  1.00 20.08  ? 212 ILE A O     1 
ATOM   2839 C CB    . ILE B 2 291 ? 126.546 132.644 96.848  1.00 20.08  ? 212 ILE A CB    1 
ATOM   2840 C CG1   . ILE B 2 291 ? 125.257 133.281 96.328  1.00 20.08  ? 212 ILE A CG1   1 
ATOM   2841 C CG2   . ILE B 2 291 ? 127.751 133.204 96.117  1.00 20.08  ? 212 ILE A CG2   1 
ATOM   2842 C CD1   . ILE B 2 291 ? 125.081 134.706 96.762  1.00 20.08  ? 212 ILE A CD1   1 
ATOM   2843 N N     . HIS B 2 292 ? 124.243 130.329 97.225  1.00 16.09  ? 213 HIS A N     1 
ATOM   2844 C CA    . HIS B 2 292 ? 123.258 129.667 98.069  1.00 16.09  ? 213 HIS A CA    1 
ATOM   2845 C C     . HIS B 2 292 ? 123.653 128.230 98.370  1.00 16.09  ? 213 HIS A C     1 
ATOM   2846 O O     . HIS B 2 292 ? 123.141 127.644 99.330  1.00 16.09  ? 213 HIS A O     1 
ATOM   2847 C CB    . HIS B 2 292 ? 121.878 129.706 97.410  1.00 16.09  ? 213 HIS A CB    1 
ATOM   2848 C CG    . HIS B 2 292 ? 121.842 129.111 96.036  1.00 16.09  ? 213 HIS A CG    1 
ATOM   2849 N ND1   . HIS B 2 292 ? 121.445 129.827 94.928  1.00 16.09  ? 213 HIS A ND1   1 
ATOM   2850 C CD2   . HIS B 2 292 ? 122.139 127.866 95.593  1.00 16.09  ? 213 HIS A CD2   1 
ATOM   2851 C CE1   . HIS B 2 292 ? 121.506 129.051 93.860  1.00 16.09  ? 213 HIS A CE1   1 
ATOM   2852 N NE2   . HIS B 2 292 ? 121.924 127.857 94.237  1.00 16.09  ? 213 HIS A NE2   1 
ATOM   2853 N N     . CYS B 2 293 ? 124.550 127.651 97.572  1.00 15.70  ? 214 CYS A N     1 
ATOM   2854 C CA    . CYS B 2 293 ? 125.050 126.310 97.835  1.00 15.70  ? 214 CYS A CA    1 
ATOM   2855 C C     . CYS B 2 293 ? 125.982 126.259 99.034  1.00 15.70  ? 214 CYS A C     1 
ATOM   2856 O O     . CYS B 2 293 ? 126.346 125.159 99.464  1.00 15.70  ? 214 CYS A O     1 
ATOM   2857 C CB    . CYS B 2 293 ? 125.776 125.770 96.602  1.00 15.70  ? 214 CYS A CB    1 
ATOM   2858 S SG    . CYS B 2 293 ? 124.809 125.839 95.079  1.00 15.70  ? 214 CYS A SG    1 
ATOM   2859 N N     . PHE B 2 294 ? 126.376 127.408 99.581  1.00 17.05  ? 215 PHE A N     1 
ATOM   2860 C CA    . PHE B 2 294 ? 127.323 127.463 100.686 1.00 17.05  ? 215 PHE A CA    1 
ATOM   2861 C C     . PHE B 2 294 ? 126.659 127.844 102.005 1.00 17.05  ? 215 PHE A C     1 
ATOM   2862 O O     . PHE B 2 294 ? 127.331 128.346 102.910 1.00 17.05  ? 215 PHE A O     1 
ATOM   2863 C CB    . PHE B 2 294 ? 128.460 128.428 100.353 1.00 17.05  ? 215 PHE A CB    1 
ATOM   2864 C CG    . PHE B 2 294 ? 129.429 127.886 99.344  1.00 17.05  ? 215 PHE A CG    1 
ATOM   2865 C CD1   . PHE B 2 294 ? 130.434 127.015 99.730  1.00 17.05  ? 215 PHE A CD1   1 
ATOM   2866 C CD2   . PHE B 2 294 ? 129.329 128.235 98.009  1.00 17.05  ? 215 PHE A CD2   1 
ATOM   2867 C CE1   . PHE B 2 294 ? 131.326 126.509 98.805  1.00 17.05  ? 215 PHE A CE1   1 
ATOM   2868 C CE2   . PHE B 2 294 ? 130.218 127.731 97.079  1.00 17.05  ? 215 PHE A CE2   1 
ATOM   2869 C CZ    . PHE B 2 294 ? 131.217 126.868 97.479  1.00 17.05  ? 215 PHE A CZ    1 
ATOM   2870 N N     . GLU B 2 295 ? 125.353 127.622 102.134 1.00 16.80  ? 216 GLU A N     1 
ATOM   2871 C CA    . GLU B 2 295 ? 124.737 127.659 103.450 1.00 16.80  ? 216 GLU A CA    1 
ATOM   2872 C C     . GLU B 2 295 ? 125.396 126.634 104.366 1.00 16.80  ? 216 GLU A C     1 
ATOM   2873 O O     . GLU B 2 295 ? 126.100 125.723 103.924 1.00 16.80  ? 216 GLU A O     1 
ATOM   2874 C CB    . GLU B 2 295 ? 123.241 127.367 103.371 1.00 16.80  ? 216 GLU A CB    1 
ATOM   2875 C CG    . GLU B 2 295 ? 122.366 128.552 103.040 1.00 16.80  ? 216 GLU A CG    1 
ATOM   2876 C CD    . GLU B 2 295 ? 120.898 128.238 103.245 1.00 16.80  ? 216 GLU A CD    1 
ATOM   2877 O OE1   . GLU B 2 295 ? 120.571 127.058 103.484 1.00 16.80  ? 216 GLU A OE1   1 
ATOM   2878 O OE2   . GLU B 2 295 ? 120.070 129.167 103.193 1.00 16.80  ? 216 GLU A OE2   1 
ATOM   2879 N N     . GLY B 2 296 ? 125.160 126.794 105.665 1.00 18.89  ? 217 GLY A N     1 
ATOM   2880 C CA    . GLY B 2 296 ? 125.672 125.867 106.647 1.00 18.89  ? 217 GLY A CA    1 
ATOM   2881 C C     . GLY B 2 296 ? 127.168 125.902 106.846 1.00 18.89  ? 217 GLY A C     1 
ATOM   2882 O O     . GLY B 2 296 ? 127.658 125.304 107.812 1.00 18.89  ? 217 GLY A O     1 
ATOM   2883 N N     . VAL B 2 297 ? 127.917 126.571 105.970 1.00 18.35  ? 218 VAL A N     1 
ATOM   2884 C CA    . VAL B 2 297 ? 129.352 126.705 106.173 1.00 18.35  ? 218 VAL A CA    1 
ATOM   2885 C C     . VAL B 2 297 ? 129.591 127.451 107.476 1.00 18.35  ? 218 VAL A C     1 
ATOM   2886 O O     . VAL B 2 297 ? 128.874 128.405 107.805 1.00 18.35  ? 218 VAL A O     1 
ATOM   2887 C CB    . VAL B 2 297 ? 130.006 127.424 104.984 1.00 18.35  ? 218 VAL A CB    1 
ATOM   2888 C CG1   . VAL B 2 297 ? 129.756 126.654 103.696 1.00 18.35  ? 218 VAL A CG1   1 
ATOM   2889 C CG2   . VAL B 2 297 ? 129.498 128.855 104.872 1.00 18.35  ? 218 VAL A CG2   1 
ATOM   2890 N N     . THR B 2 298 ? 130.597 127.014 108.231 1.00 20.28  ? 219 THR A N     1 
ATOM   2891 C CA    . THR B 2 298 ? 130.848 127.604 109.539 1.00 20.28  ? 219 THR A CA    1 
ATOM   2892 C C     . THR B 2 298 ? 131.150 129.093 109.417 1.00 20.28  ? 219 THR A C     1 
ATOM   2893 O O     . THR B 2 298 ? 130.660 129.906 110.207 1.00 20.28  ? 219 THR A O     1 
ATOM   2894 C CB    . THR B 2 298 ? 131.996 126.866 110.229 1.00 20.28  ? 219 THR A CB    1 
ATOM   2895 O OG1   . THR B 2 298 ? 131.687 125.469 110.302 1.00 20.28  ? 219 THR A OG1   1 
ATOM   2896 C CG2   . THR B 2 298 ? 132.214 127.405 111.635 1.00 20.28  ? 219 THR A CG2   1 
ATOM   2897 N N     . ALA B 2 299 ? 131.952 129.472 108.424 1.00 20.08  ? 220 ALA A N     1 
ATOM   2898 C CA    . ALA B 2 299 ? 132.342 130.862 108.250 1.00 20.08  ? 220 ALA A CA    1 
ATOM   2899 C C     . ALA B 2 299 ? 132.734 131.133 106.800 1.00 20.08  ? 220 ALA A C     1 
ATOM   2900 O O     . ALA B 2 299 ? 132.927 130.217 105.986 1.00 20.08  ? 220 ALA A O     1 
ATOM   2901 C CB    . ALA B 2 299 ? 133.494 131.230 109.193 1.00 20.08  ? 220 ALA A CB    1 
ATOM   2902 N N     . ILE B 2 300 ? 132.842 132.424 106.493 1.00 21.15  ? 221 ILE A N     1 
ATOM   2903 C CA    . ILE B 2 300 ? 133.355 132.917 105.222 1.00 21.15  ? 221 ILE A CA    1 
ATOM   2904 C C     . ILE B 2 300 ? 134.657 133.634 105.551 1.00 21.15  ? 221 ILE A C     1 
ATOM   2905 O O     . ILE B 2 300 ? 134.665 134.600 106.321 1.00 21.15  ? 221 ILE A O     1 
ATOM   2906 C CB    . ILE B 2 300 ? 132.376 133.858 104.516 1.00 21.15  ? 221 ILE A CB    1 
ATOM   2907 C CG1   . ILE B 2 300 ? 131.008 133.194 104.378 1.00 21.15  ? 221 ILE A CG1   1 
ATOM   2908 C CG2   . ILE B 2 300 ? 132.915 134.249 103.143 1.00 21.15  ? 221 ILE A CG2   1 
ATOM   2909 C CD1   . ILE B 2 300 ? 130.035 133.969 103.520 1.00 21.15  ? 221 ILE A CD1   1 
ATOM   2910 N N     . ILE B 2 301 ? 135.759 133.163 104.974 1.00 24.58  ? 222 ILE A N     1 
ATOM   2911 C CA    . ILE B 2 301 ? 137.060 133.816 105.077 1.00 24.58  ? 222 ILE A CA    1 
ATOM   2912 C C     . ILE B 2 301 ? 137.168 134.780 103.900 1.00 24.58  ? 222 ILE A C     1 
ATOM   2913 O O     . ILE B 2 301 ? 137.287 134.359 102.749 1.00 24.58  ? 222 ILE A O     1 
ATOM   2914 C CB    . ILE B 2 301 ? 138.204 132.802 105.089 1.00 24.58  ? 222 ILE A CB    1 
ATOM   2915 C CG1   . ILE B 2 301 ? 138.073 131.876 106.303 1.00 24.58  ? 222 ILE A CG1   1 
ATOM   2916 C CG2   . ILE B 2 301 ? 139.544 133.515 105.042 1.00 24.58  ? 222 ILE A CG2   1 
ATOM   2917 C CD1   . ILE B 2 301 ? 138.963 130.658 106.255 1.00 24.58  ? 222 ILE A CD1   1 
ATOM   2918 N N     . PHE B 2 302 ? 137.113 136.077 104.186 1.00 30.78  ? 223 PHE A N     1 
ATOM   2919 C CA    . PHE B 2 302 ? 137.212 137.115 103.171 1.00 30.78  ? 223 PHE A CA    1 
ATOM   2920 C C     . PHE B 2 302 ? 138.565 137.798 103.297 1.00 30.78  ? 223 PHE A C     1 
ATOM   2921 O O     . PHE B 2 302 ? 138.938 138.252 104.383 1.00 30.78  ? 223 PHE A O     1 
ATOM   2922 C CB    . PHE B 2 302 ? 136.078 138.131 103.321 1.00 30.78  ? 223 PHE A CB    1 
ATOM   2923 C CG    . PHE B 2 302 ? 136.027 139.158 102.224 1.00 30.78  ? 223 PHE A CG    1 
ATOM   2924 C CD1   . PHE B 2 302 ? 136.904 140.229 102.210 1.00 30.78  ? 223 PHE A CD1   1 
ATOM   2925 C CD2   . PHE B 2 302 ? 135.097 139.052 101.205 1.00 30.78  ? 223 PHE A CD2   1 
ATOM   2926 C CE1   . PHE B 2 302 ? 136.853 141.173 101.202 1.00 30.78  ? 223 PHE A CE1   1 
ATOM   2927 C CE2   . PHE B 2 302 ? 135.040 139.993 100.196 1.00 30.78  ? 223 PHE A CE2   1 
ATOM   2928 C CZ    . PHE B 2 302 ? 135.919 141.053 100.194 1.00 30.78  ? 223 PHE A CZ    1 
ATOM   2929 N N     . CYS B 2 303 ? 139.295 137.866 102.189 1.00 35.77  ? 224 CYS A N     1 
ATOM   2930 C CA    . CYS B 2 303 ? 140.649 138.397 102.172 1.00 35.77  ? 224 CYS A CA    1 
ATOM   2931 C C     . CYS B 2 303 ? 140.667 139.738 101.455 1.00 35.77  ? 224 CYS A C     1 
ATOM   2932 O O     . CYS B 2 303 ? 140.074 139.889 100.382 1.00 35.77  ? 224 CYS A O     1 
ATOM   2933 C CB    . CYS B 2 303 ? 141.609 137.425 101.484 1.00 35.77  ? 224 CYS A CB    1 
ATOM   2934 S SG    . CYS B 2 303 ? 141.918 135.916 102.421 1.00 35.77  ? 224 CYS A SG    1 
ATOM   2935 N N     . VAL B 2 304 ? 141.342 140.714 102.063 1.00 43.43  ? 225 VAL A N     1 
ATOM   2936 C CA    . VAL B 2 304 ? 141.533 142.029 101.470 1.00 43.43  ? 225 VAL A CA    1 
ATOM   2937 C C     . VAL B 2 304 ? 142.990 142.426 101.657 1.00 43.43  ? 225 VAL A C     1 
ATOM   2938 O O     . VAL B 2 304 ? 143.674 141.958 102.569 1.00 43.43  ? 225 VAL A O     1 
ATOM   2939 C CB    . VAL B 2 304 ? 140.599 143.094 102.090 1.00 43.43  ? 225 VAL A CB    1 
ATOM   2940 C CG1   . VAL B 2 304 ? 140.937 143.313 103.558 1.00 43.43  ? 225 VAL A CG1   1 
ATOM   2941 C CG2   . VAL B 2 304 ? 140.688 144.399 101.316 1.00 43.43  ? 225 VAL A CG2   1 
ATOM   2942 N N     . ALA B 2 305 ? 143.461 143.301 100.774 1.00 52.39  ? 226 ALA A N     1 
ATOM   2943 C CA    . ALA B 2 305 ? 144.833 143.785 100.798 1.00 52.39  ? 226 ALA A CA    1 
ATOM   2944 C C     . ALA B 2 305 ? 144.834 145.279 101.086 1.00 52.39  ? 226 ALA A C     1 
ATOM   2945 O O     . ALA B 2 305 ? 144.137 146.045 100.412 1.00 52.39  ? 226 ALA A O     1 
ATOM   2946 C CB    . ALA B 2 305 ? 145.542 143.498 99.472  1.00 52.39  ? 226 ALA A CB    1 
ATOM   2947 N N     . LEU B 2 306 ? 145.615 145.687 102.086 1.00 60.79  ? 227 LEU A N     1 
ATOM   2948 C CA    . LEU B 2 306 ? 145.756 147.099 102.413 1.00 60.79  ? 227 LEU A CA    1 
ATOM   2949 C C     . LEU B 2 306 ? 146.476 147.885 101.327 1.00 60.79  ? 227 LEU A C     1 
ATOM   2950 O O     . LEU B 2 306 ? 146.347 149.113 101.285 1.00 60.79  ? 227 LEU A O     1 
ATOM   2951 C CB    . LEU B 2 306 ? 146.511 147.259 103.734 1.00 60.79  ? 227 LEU A CB    1 
ATOM   2952 C CG    . LEU B 2 306 ? 146.674 148.707 104.234 1.00 60.79  ? 227 LEU A CG    1 
ATOM   2953 C CD1   . LEU B 2 306 ? 145.434 149.556 104.592 1.00 60.79  ? 227 LEU A CD1   1 
ATOM   2954 C CD2   . LEU B 2 306 ? 148.028 149.200 104.803 1.00 60.79  ? 227 LEU A CD2   1 
ATOM   2955 N N     . SER B 2 307 ? 147.225 147.214 100.458 1.00 63.53  ? 228 SER A N     1 
ATOM   2956 C CA    . SER B 2 307 ? 147.948 147.885 99.388  1.00 63.53  ? 228 SER A CA    1 
ATOM   2957 C C     . SER B 2 307 ? 146.981 148.450 98.353  1.00 63.53  ? 228 SER A C     1 
ATOM   2958 O O     . SER B 2 307 ? 145.848 147.983 98.228  1.00 63.53  ? 228 SER A O     1 
ATOM   2959 C CB    . SER B 2 307 ? 148.929 146.918 98.724  1.00 63.53  ? 228 SER A CB    1 
ATOM   2960 O OG    . SER B 2 307 ? 149.929 146.500 99.638  1.00 63.53  ? 228 SER A OG    1 
ATOM   2961 N N     . ASN B 2 320 ? 140.547 152.285 92.467  1.00 57.82  ? 241 ASN A N     1 
ATOM   2962 C CA    . ASN B 2 320 ? 139.917 152.209 93.779  1.00 57.82  ? 241 ASN A CA    1 
ATOM   2963 C C     . ASN B 2 320 ? 139.541 150.770 94.115  1.00 57.82  ? 241 ASN A C     1 
ATOM   2964 O O     . ASN B 2 320 ? 138.376 150.466 94.374  1.00 57.82  ? 241 ASN A O     1 
ATOM   2965 C CB    . ASN B 2 320 ? 138.678 153.105 93.830  1.00 57.82  ? 241 ASN A CB    1 
ATOM   2966 C CG    . ASN B 2 320 ? 137.736 152.861 92.667  1.00 57.82  ? 241 ASN A CG    1 
ATOM   2967 O OD1   . ASN B 2 320 ? 136.871 151.988 92.726  1.00 57.82  ? 241 ASN A OD1   1 
ATOM   2968 N ND2   . ASN B 2 320 ? 137.902 153.634 91.601  1.00 57.82  ? 241 ASN A ND2   1 
ATOM   2969 N N     . ARG B 2 321 ? 140.539 149.884 94.110  1.00 56.54  ? 242 ARG A N     1 
ATOM   2970 C CA    . ARG B 2 321 ? 140.281 148.482 94.418  1.00 56.54  ? 242 ARG A CA    1 
ATOM   2971 C C     . ARG B 2 321 ? 139.772 148.310 95.843  1.00 56.54  ? 242 ARG A C     1 
ATOM   2972 O O     . ARG B 2 321 ? 139.080 147.329 96.142  1.00 56.54  ? 242 ARG A O     1 
ATOM   2973 C CB    . ARG B 2 321 ? 141.551 147.660 94.200  1.00 56.54  ? 242 ARG A CB    1 
ATOM   2974 C CG    . ARG B 2 321 ? 142.065 147.710 92.770  1.00 56.54  ? 242 ARG A CG    1 
ATOM   2975 C CD    . ARG B 2 321 ? 143.023 146.572 92.463  1.00 56.54  ? 242 ARG A CD    1 
ATOM   2976 N NE    . ARG B 2 321 ? 143.029 146.247 91.040  1.00 56.54  ? 242 ARG A NE    1 
ATOM   2977 C CZ    . ARG B 2 321 ? 144.114 146.158 90.280  1.00 56.54  ? 242 ARG A CZ    1 
ATOM   2978 N NH1   . ARG B 2 321 ? 145.329 146.348 90.773  1.00 56.54  ? 242 ARG A NH1   1 
ATOM   2979 N NH2   . ARG B 2 321 ? 143.978 145.867 88.990  1.00 56.54  ? 242 ARG A NH2   1 
ATOM   2980 N N     . MET B 2 322 ? 140.101 149.247 96.734  1.00 53.40  ? 243 MET A N     1 
ATOM   2981 C CA    . MET B 2 322 ? 139.560 149.191 98.086  1.00 53.40  ? 243 MET A CA    1 
ATOM   2982 C C     . MET B 2 322 ? 138.043 149.322 98.069  1.00 53.40  ? 243 MET A C     1 
ATOM   2983 O O     . MET B 2 322 ? 137.348 148.629 98.819  1.00 53.40  ? 243 MET A O     1 
ATOM   2984 C CB    . MET B 2 322 ? 140.187 150.284 98.950  1.00 53.40  ? 243 MET A CB    1 
ATOM   2985 C CG    . MET B 2 322 ? 139.895 150.140 100.435 1.00 53.40  ? 243 MET A CG    1 
ATOM   2986 S SD    . MET B 2 322 ? 140.633 148.658 101.149 1.00 53.40  ? 243 MET A SD    1 
ATOM   2987 C CE    . MET B 2 322 ? 142.258 149.264 101.595 1.00 53.40  ? 243 MET A CE    1 
ATOM   2988 N N     . HIS B 2 323 ? 137.511 150.204 97.220  1.00 54.38  ? 244 HIS A N     1 
ATOM   2989 C CA    . HIS B 2 323 ? 136.063 150.294 97.068  1.00 54.38  ? 244 HIS A CA    1 
ATOM   2990 C C     . HIS B 2 323 ? 135.485 149.012 96.482  1.00 54.38  ? 244 HIS A C     1 
ATOM   2991 O O     . HIS B 2 323 ? 134.362 148.625 96.827  1.00 54.38  ? 244 HIS A O     1 
ATOM   2992 C CB    . HIS B 2 323 ? 135.700 151.493 96.194  1.00 54.38  ? 244 HIS A CB    1 
ATOM   2993 C CG    . HIS B 2 323 ? 135.899 152.813 96.871  1.00 54.38  ? 244 HIS A CG    1 
ATOM   2994 N ND1   . HIS B 2 323 ? 137.124 153.229 97.346  1.00 54.38  ? 244 HIS A ND1   1 
ATOM   2995 C CD2   . HIS B 2 323 ? 135.028 153.811 97.153  1.00 54.38  ? 244 HIS A CD2   1 
ATOM   2996 C CE1   . HIS B 2 323 ? 137.000 154.425 97.892  1.00 54.38  ? 244 HIS A CE1   1 
ATOM   2997 N NE2   . HIS B 2 323 ? 135.738 154.801 97.788  1.00 54.38  ? 244 HIS A NE2   1 
ATOM   2998 N N     . GLU B 2 324 ? 136.229 148.342 95.599  1.00 49.88  ? 245 GLU A N     1 
ATOM   2999 C CA    . GLU B 2 324 ? 135.789 147.041 95.108  1.00 49.88  ? 245 GLU A CA    1 
ATOM   3000 C C     . GLU B 2 324 ? 135.673 146.044 96.255  1.00 49.88  ? 245 GLU A C     1 
ATOM   3001 O O     . GLU B 2 324 ? 134.683 145.308 96.358  1.00 49.88  ? 245 GLU A O     1 
ATOM   3002 C CB    . GLU B 2 324 ? 136.762 146.527 94.047  1.00 49.88  ? 245 GLU A CB    1 
ATOM   3003 C CG    . GLU B 2 324 ? 136.189 145.441 93.151  1.00 49.88  ? 245 GLU A CG    1 
ATOM   3004 C CD    . GLU B 2 324 ? 135.129 145.969 92.203  1.00 49.88  ? 245 GLU A CD    1 
ATOM   3005 O OE1   . GLU B 2 324 ? 135.178 147.170 91.865  1.00 49.88  ? 245 GLU A OE1   1 
ATOM   3006 O OE2   . GLU B 2 324 ? 134.247 145.183 91.796  1.00 49.88  ? 245 GLU A OE2   1 
ATOM   3007 N N     . SER B 2 325 ? 136.673 146.018 97.138  1.00 46.87  ? 246 SER A N     1 
ATOM   3008 C CA    . SER B 2 325 ? 136.609 145.135 98.296  1.00 46.87  ? 246 SER A CA    1 
ATOM   3009 C C     . SER B 2 325 ? 135.441 145.502 99.203  1.00 46.87  ? 246 SER A C     1 
ATOM   3010 O O     . SER B 2 325 ? 134.765 144.618 99.740  1.00 46.87  ? 246 SER A O     1 
ATOM   3011 C CB    . SER B 2 325 ? 137.926 145.189 99.069  1.00 46.87  ? 246 SER A CB    1 
ATOM   3012 O OG    . SER B 2 325 ? 139.030 144.990 98.205  1.00 46.87  ? 246 SER A OG    1 
ATOM   3013 N N     . MET B 2 326 ? 135.192 146.799 99.392  1.00 48.15  ? 247 MET A N     1 
ATOM   3014 C CA    . MET B 2 326 ? 134.080 147.218 100.240 1.00 48.15  ? 247 MET A CA    1 
ATOM   3015 C C     . MET B 2 326 ? 132.743 146.770 99.663  1.00 48.15  ? 247 MET A C     1 
ATOM   3016 O O     . MET B 2 326 ? 131.880 146.275 100.398 1.00 48.15  ? 247 MET A O     1 
ATOM   3017 C CB    . MET B 2 326 ? 134.090 148.736 100.428 1.00 48.15  ? 247 MET A CB    1 
ATOM   3018 C CG    . MET B 2 326 ? 135.360 149.286 101.052 1.00 48.15  ? 247 MET A CG    1 
ATOM   3019 S SD    . MET B 2 326 ? 135.045 150.686 102.141 1.00 48.15  ? 247 MET A SD    1 
ATOM   3020 C CE    . MET B 2 326 ? 136.683 151.400 102.257 1.00 48.15  ? 247 MET A CE    1 
ATOM   3021 N N     . LYS B 2 327 ? 132.543 146.945 98.355  1.00 45.97  ? 248 LYS A N     1 
ATOM   3022 C CA    . LYS B 2 327 ? 131.284 146.517 97.754  1.00 45.97  ? 248 LYS A CA    1 
ATOM   3023 C C     . LYS B 2 327 ? 131.140 145.002 97.811  1.00 45.97  ? 248 LYS A C     1 
ATOM   3024 O O     . LYS B 2 327 ? 130.041 144.488 98.044  1.00 45.97  ? 248 LYS A O     1 
ATOM   3025 C CB    . LYS B 2 327 ? 131.171 147.019 96.313  1.00 45.97  ? 248 LYS A CB    1 
ATOM   3026 C CG    . LYS B 2 327 ? 132.212 146.469 95.365  1.00 45.97  ? 248 LYS A CG    1 
ATOM   3027 C CD    . LYS B 2 327 ? 131.975 146.942 93.940  1.00 45.97  ? 248 LYS A CD    1 
ATOM   3028 C CE    . LYS B 2 327 ? 132.325 148.410 93.766  1.00 45.97  ? 248 LYS A CE    1 
ATOM   3029 N NZ    . LYS B 2 327 ? 132.224 148.833 92.343  1.00 45.97  ? 248 LYS A NZ    1 
ATOM   3030 N N     . LEU B 2 328 ? 132.238 144.266 97.613  1.00 40.37  ? 249 LEU A N     1 
ATOM   3031 C CA    . LEU B 2 328 ? 132.179 142.814 97.755  1.00 40.37  ? 249 LEU A CA    1 
ATOM   3032 C C     . LEU B 2 328 ? 131.785 142.415 99.174  1.00 40.37  ? 249 LEU A C     1 
ATOM   3033 O O     . LEU B 2 328 ? 130.960 141.515 99.372  1.00 40.37  ? 249 LEU A O     1 
ATOM   3034 C CB    . LEU B 2 328 ? 133.525 142.192 97.379  1.00 40.37  ? 249 LEU A CB    1 
ATOM   3035 C CG    . LEU B 2 328 ? 133.692 141.685 95.942  1.00 40.37  ? 249 LEU A CG    1 
ATOM   3036 C CD1   . LEU B 2 328 ? 132.793 140.483 95.696  1.00 40.37  ? 249 LEU A CD1   1 
ATOM   3037 C CD2   . LEU B 2 328 ? 133.415 142.779 94.921  1.00 40.37  ? 249 LEU A CD2   1 
ATOM   3038 N N     . PHE B 2 329 ? 132.379 143.067 100.175 1.00 36.42  ? 250 PHE A N     1 
ATOM   3039 C CA    . PHE B 2 329 ? 132.070 142.745 101.563 1.00 36.42  ? 250 PHE A CA    1 
ATOM   3040 C C     . PHE B 2 329 ? 130.614 143.052 101.889 1.00 36.42  ? 250 PHE A C     1 
ATOM   3041 O O     . PHE B 2 329 ? 129.943 142.257 102.561 1.00 36.42  ? 250 PHE A O     1 
ATOM   3042 C CB    . PHE B 2 329 ? 133.001 143.529 102.486 1.00 36.42  ? 250 PHE A CB    1 
ATOM   3043 C CG    . PHE B 2 329 ? 132.804 143.237 103.942 1.00 36.42  ? 250 PHE A CG    1 
ATOM   3044 C CD1   . PHE B 2 329 ? 133.284 142.061 104.492 1.00 36.42  ? 250 PHE A CD1   1 
ATOM   3045 C CD2   . PHE B 2 329 ? 132.137 144.131 104.759 1.00 36.42  ? 250 PHE A CD2   1 
ATOM   3046 C CE1   . PHE B 2 329 ? 133.110 141.787 105.833 1.00 36.42  ? 250 PHE A CE1   1 
ATOM   3047 C CE2   . PHE B 2 329 ? 131.958 143.862 106.100 1.00 36.42  ? 250 PHE A CE2   1 
ATOM   3048 C CZ    . PHE B 2 329 ? 132.444 142.687 106.637 1.00 36.42  ? 250 PHE A CZ    1 
ATOM   3049 N N     . ASP B 2 330 ? 130.112 144.195 101.419 1.00 38.66  ? 251 ASP A N     1 
ATOM   3050 C CA    . ASP B 2 330 ? 128.701 144.517 101.599 1.00 38.66  ? 251 ASP A CA    1 
ATOM   3051 C C     . ASP B 2 330 ? 127.826 143.467 100.930 1.00 38.66  ? 251 ASP A C     1 
ATOM   3052 O O     . ASP B 2 330 ? 126.808 143.040 101.487 1.00 38.66  ? 251 ASP A O     1 
ATOM   3053 C CB    . ASP B 2 330 ? 128.407 145.905 101.027 1.00 38.66  ? 251 ASP A CB    1 
ATOM   3054 C CG    . ASP B 2 330 ? 127.014 146.403 101.375 1.00 38.66  ? 251 ASP A CG    1 
ATOM   3055 O OD1   . ASP B 2 330 ? 126.126 145.571 101.655 1.00 38.66  ? 251 ASP A OD1   1 
ATOM   3056 O OD2   . ASP B 2 330 ? 126.808 147.634 101.370 1.00 38.66  ? 251 ASP A OD2   1 
ATOM   3057 N N     . SER B 2 331 ? 128.214 143.034 99.730  1.00 36.43  ? 252 SER A N     1 
ATOM   3058 C CA    . SER B 2 331 ? 127.448 142.010 99.033  1.00 36.43  ? 252 SER A CA    1 
ATOM   3059 C C     . SER B 2 331 ? 127.372 140.731 99.852  1.00 36.43  ? 252 SER A C     1 
ATOM   3060 O O     . SER B 2 331 ? 126.282 140.192 100.064 1.00 36.43  ? 252 SER A O     1 
ATOM   3061 C CB    . SER B 2 331 ? 128.070 141.733 97.666  1.00 36.43  ? 252 SER A CB    1 
ATOM   3062 O OG    . SER B 2 331 ? 129.407 141.285 97.800  1.00 36.43  ? 252 SER A OG    1 
ATOM   3063 N N     . ILE B 2 332 ? 128.515 140.242 100.342 1.00 32.67  ? 253 ILE A N     1 
ATOM   3064 C CA    . ILE B 2 332 ? 128.513 138.972 101.066 1.00 32.67  ? 253 ILE A CA    1 
ATOM   3065 C C     . ILE B 2 332 ? 127.709 139.095 102.356 1.00 32.67  ? 253 ILE A C     1 
ATOM   3066 O O     . ILE B 2 332 ? 126.934 138.199 102.706 1.00 32.67  ? 253 ILE A O     1 
ATOM   3067 C CB    . ILE B 2 332 ? 129.946 138.469 101.333 1.00 32.67  ? 253 ILE A CB    1 
ATOM   3068 C CG1   . ILE B 2 332 ? 130.663 139.332 102.372 1.00 32.67  ? 253 ILE A CG1   1 
ATOM   3069 C CG2   . ILE B 2 332 ? 130.735 138.390 100.035 1.00 32.67  ? 253 ILE A CG2   1 
ATOM   3070 C CD1   . ILE B 2 332 ? 132.045 138.844 102.714 1.00 32.67  ? 253 ILE A CD1   1 
ATOM   3071 N N     . CYS B 2 333 ? 127.877 140.203 103.085 1.00 31.98  ? 254 CYS A N     1 
ATOM   3072 C CA    . CYS B 2 333 ? 127.137 140.354 104.335 1.00 31.98  ? 254 CYS A CA    1 
ATOM   3073 C C     . CYS B 2 333 ? 125.638 140.484 104.093 1.00 31.98  ? 254 CYS A C     1 
ATOM   3074 O O     . CYS B 2 333 ? 124.838 140.011 104.907 1.00 31.98  ? 254 CYS A O     1 
ATOM   3075 C CB    . CYS B 2 333 ? 127.647 141.565 105.114 1.00 31.98  ? 254 CYS A CB    1 
ATOM   3076 S SG    . CYS B 2 333 ? 129.398 141.502 105.542 1.00 31.98  ? 254 CYS A SG    1 
ATOM   3077 N N     . ASN B 2 334 ? 125.239 141.115 102.987 1.00 37.45  ? 255 ASN A N     1 
ATOM   3078 C CA    . ASN B 2 334 ? 123.830 141.419 102.763 1.00 37.45  ? 255 ASN A CA    1 
ATOM   3079 C C     . ASN B 2 334 ? 123.025 140.183 102.374 1.00 37.45  ? 255 ASN A C     1 
ATOM   3080 O O     . ASN B 2 334 ? 121.790 140.214 102.412 1.00 37.45  ? 255 ASN A O     1 
ATOM   3081 C CB    . ASN B 2 334 ? 123.700 142.494 101.681 1.00 37.45  ? 255 ASN A CB    1 
ATOM   3082 C CG    . ASN B 2 334 ? 122.315 143.115 101.634 1.00 37.45  ? 255 ASN A CG    1 
ATOM   3083 O OD1   . ASN B 2 334 ? 121.439 142.773 102.428 1.00 37.45  ? 255 ASN A OD1   1 
ATOM   3084 N ND2   . ASN B 2 334 ? 122.112 144.036 100.698 1.00 37.45  ? 255 ASN A ND2   1 
ATOM   3085 N N     . ASN B 2 335 ? 123.688 139.093 101.991 1.00 26.04  ? 256 ASN A N     1 
ATOM   3086 C CA    . ASN B 2 335 ? 122.966 137.928 101.491 1.00 26.04  ? 256 ASN A CA    1 
ATOM   3087 C C     . ASN B 2 335 ? 121.990 137.397 102.525 1.00 26.04  ? 256 ASN A C     1 
ATOM   3088 O O     . ASN B 2 335 ? 122.296 137.344 103.719 1.00 26.04  ? 256 ASN A O     1 
ATOM   3089 C CB    . ASN B 2 335 ? 123.933 136.813 101.089 1.00 26.04  ? 256 ASN A CB    1 
ATOM   3090 C CG    . ASN B 2 335 ? 124.914 137.246 100.038 1.00 26.04  ? 256 ASN A CG    1 
ATOM   3091 O OD1   . ASN B 2 335 ? 125.908 137.890 100.340 1.00 26.04  ? 256 ASN A OD1   1 
ATOM   3092 N ND2   . ASN B 2 335 ? 124.627 136.918 98.787  1.00 26.04  ? 256 ASN A ND2   1 
ATOM   3093 N N     . LYS B 2 336 ? 120.809 137.002 102.050 1.00 22.49  ? 257 LYS A N     1 
ATOM   3094 C CA    . LYS B 2 336 ? 119.885 136.258 102.894 1.00 22.49  ? 257 LYS A CA    1 
ATOM   3095 C C     . LYS B 2 336 ? 120.447 134.890 103.258 1.00 22.49  ? 257 LYS A C     1 
ATOM   3096 O O     . LYS B 2 336 ? 120.000 134.276 104.233 1.00 22.49  ? 257 LYS A O     1 
ATOM   3097 C CB    . LYS B 2 336 ? 118.541 136.114 102.182 1.00 22.49  ? 257 LYS A CB    1 
ATOM   3098 C CG    . LYS B 2 336 ? 118.605 135.260 100.925 1.00 22.49  ? 257 LYS A CG    1 
ATOM   3099 C CD    . LYS B 2 336 ? 117.257 135.177 100.228 1.00 22.49  ? 257 LYS A CD    1 
ATOM   3100 C CE    . LYS B 2 336 ? 116.919 136.468 99.500  1.00 22.49  ? 257 LYS A CE    1 
ATOM   3101 N NZ    . LYS B 2 336 ? 117.860 136.746 98.379  1.00 22.49  ? 257 LYS A NZ    1 
ATOM   3102 N N     . TRP B 2 337 ? 121.420 134.396 102.492 1.00 18.28  ? 258 TRP A N     1 
ATOM   3103 C CA    . TRP B 2 337 ? 121.999 133.081 102.728 1.00 18.28  ? 258 TRP A CA    1 
ATOM   3104 C C     . TRP B 2 337 ? 123.142 133.103 103.733 1.00 18.28  ? 258 TRP A C     1 
ATOM   3105 O O     . TRP B 2 337 ? 123.584 132.034 104.164 1.00 18.28  ? 258 TRP A O     1 
ATOM   3106 C CB    . TRP B 2 337 ? 122.511 132.472 101.417 1.00 18.28  ? 258 TRP A CB    1 
ATOM   3107 C CG    . TRP B 2 337 ? 121.531 132.508 100.288 1.00 18.28  ? 258 TRP A CG    1 
ATOM   3108 C CD1   . TRP B 2 337 ? 121.673 133.156 99.096  1.00 18.28  ? 258 TRP A CD1   1 
ATOM   3109 C CD2   . TRP B 2 337 ? 120.245 131.884 100.254 1.00 18.28  ? 258 TRP A CD2   1 
ATOM   3110 N NE1   . TRP B 2 337 ? 120.560 132.960 98.317  1.00 18.28  ? 258 TRP A NE1   1 
ATOM   3111 C CE2   . TRP B 2 337 ? 119.667 132.185 99.007  1.00 18.28  ? 258 TRP A CE2   1 
ATOM   3112 C CE3   . TRP B 2 337 ? 119.528 131.099 101.157 1.00 18.28  ? 258 TRP A CE3   1 
ATOM   3113 C CZ2   . TRP B 2 337 ? 118.405 131.725 98.642  1.00 18.28  ? 258 TRP A CZ2   1 
ATOM   3114 C CZ3   . TRP B 2 337 ? 118.279 130.644 100.794 1.00 18.28  ? 258 TRP A CZ3   1 
ATOM   3115 C CH2   . TRP B 2 337 ? 117.729 130.957 99.550  1.00 18.28  ? 258 TRP A CH2   1 
ATOM   3116 N N     . PHE B 2 338 ? 123.630 134.283 104.118 1.00 22.24  ? 259 PHE A N     1 
ATOM   3117 C CA    . PHE B 2 338 ? 124.772 134.360 105.018 1.00 22.24  ? 259 PHE A CA    1 
ATOM   3118 C C     . PHE B 2 338 ? 124.502 135.236 106.236 1.00 22.24  ? 259 PHE A C     1 
ATOM   3119 O O     . PHE B 2 338 ? 125.459 135.680 106.882 1.00 22.24  ? 259 PHE A O     1 
ATOM   3120 C CB    . PHE B 2 338 ? 126.005 134.883 104.274 1.00 22.24  ? 259 PHE A CB    1 
ATOM   3121 C CG    . PHE B 2 338 ? 126.486 133.970 103.182 1.00 22.24  ? 259 PHE A CG    1 
ATOM   3122 C CD1   . PHE B 2 338 ? 127.014 132.726 103.480 1.00 22.24  ? 259 PHE A CD1   1 
ATOM   3123 C CD2   . PHE B 2 338 ? 126.426 134.364 101.857 1.00 22.24  ? 259 PHE A CD2   1 
ATOM   3124 C CE1   . PHE B 2 338 ? 127.461 131.889 102.479 1.00 22.24  ? 259 PHE A CE1   1 
ATOM   3125 C CE2   . PHE B 2 338 ? 126.872 133.530 100.853 1.00 22.24  ? 259 PHE A CE2   1 
ATOM   3126 C CZ    . PHE B 2 338 ? 127.391 132.292 101.165 1.00 22.24  ? 259 PHE A CZ    1 
ATOM   3127 N N     . THR B 2 339 ? 123.241 135.498 106.573 1.00 31.10  ? 260 THR A N     1 
ATOM   3128 C CA    . THR B 2 339 ? 122.908 136.317 107.729 1.00 31.10  ? 260 THR A CA    1 
ATOM   3129 C C     . THR B 2 339 ? 123.292 135.664 109.050 1.00 31.10  ? 260 THR A C     1 
ATOM   3130 O O     . THR B 2 339 ? 123.404 136.367 110.060 1.00 31.10  ? 260 THR A O     1 
ATOM   3131 C CB    . THR B 2 339 ? 121.408 136.628 107.742 1.00 31.10  ? 260 THR A CB    1 
ATOM   3132 O OG1   . THR B 2 339 ? 120.987 137.022 106.431 1.00 31.10  ? 260 THR A OG1   1 
ATOM   3133 C CG2   . THR B 2 339 ? 121.102 137.747 108.726 1.00 31.10  ? 260 THR A CG2   1 
ATOM   3134 N N     . ASP B 2 340 ? 123.496 134.349 109.067 1.00 29.16  ? 261 ASP A N     1 
ATOM   3135 C CA    . ASP B 2 340 ? 123.837 133.623 110.280 1.00 29.16  ? 261 ASP A CA    1 
ATOM   3136 C C     . ASP B 2 340 ? 125.294 133.182 110.322 1.00 29.16  ? 261 ASP A C     1 
ATOM   3137 O O     . ASP B 2 340 ? 125.750 132.703 111.365 1.00 29.16  ? 261 ASP A O     1 
ATOM   3138 C CB    . ASP B 2 340 ? 122.929 132.398 110.425 1.00 29.16  ? 261 ASP A CB    1 
ATOM   3139 C CG    . ASP B 2 340 ? 121.489 132.772 110.719 1.00 29.16  ? 261 ASP A CG    1 
ATOM   3140 O OD1   . ASP B 2 340 ? 121.263 133.832 111.340 1.00 29.16  ? 261 ASP A OD1   1 
ATOM   3141 O OD2   . ASP B 2 340 ? 120.582 132.008 110.324 1.00 29.16  ? 261 ASP A OD2   1 
ATOM   3142 N N     . THR B 2 341 ? 126.035 133.335 109.227 1.00 21.89  ? 262 THR A N     1 
ATOM   3143 C CA    . THR B 2 341 ? 127.405 132.851 109.129 1.00 21.89  ? 262 THR A CA    1 
ATOM   3144 C C     . THR B 2 341 ? 128.365 133.993 109.415 1.00 21.89  ? 262 THR A C     1 
ATOM   3145 O O     . THR B 2 341 ? 128.331 135.022 108.734 1.00 21.89  ? 262 THR A O     1 
ATOM   3146 C CB    . THR B 2 341 ? 127.696 132.269 107.743 1.00 21.89  ? 262 THR A CB    1 
ATOM   3147 O OG1   . THR B 2 341 ? 127.535 133.289 106.751 1.00 21.89  ? 262 THR A OG1   1 
ATOM   3148 C CG2   . THR B 2 341 ? 126.752 131.116 107.435 1.00 21.89  ? 262 THR A CG2   1 
ATOM   3149 N N     . SER B 2 342 ? 129.223 133.807 110.412 1.00 22.69  ? 263 SER A N     1 
ATOM   3150 C CA    . SER B 2 342 ? 130.237 134.799 110.717 1.00 22.69  ? 263 SER A CA    1 
ATOM   3151 C C     . SER B 2 342 ? 131.181 134.968 109.529 1.00 22.69  ? 263 SER A C     1 
ATOM   3152 O O     . SER B 2 342 ? 131.226 134.146 108.610 1.00 22.69  ? 263 SER A O     1 
ATOM   3153 C CB    . SER B 2 342 ? 131.020 134.396 111.964 1.00 22.69  ? 263 SER A CB    1 
ATOM   3154 O OG    . SER B 2 342 ? 130.186 134.392 113.109 1.00 22.69  ? 263 SER A OG    1 
ATOM   3155 N N     . ILE B 2 343 ? 131.942 136.058 109.552 1.00 23.98  ? 264 ILE A N     1 
ATOM   3156 C CA    . ILE B 2 343 ? 132.890 136.380 108.494 1.00 23.98  ? 264 ILE A CA    1 
ATOM   3157 C C     . ILE B 2 343 ? 134.243 136.647 109.133 1.00 23.98  ? 264 ILE A C     1 
ATOM   3158 O O     . ILE B 2 343 ? 134.339 137.417 110.096 1.00 23.98  ? 264 ILE A O     1 
ATOM   3159 C CB    . ILE B 2 343 ? 132.430 137.594 107.664 1.00 23.98  ? 264 ILE A CB    1 
ATOM   3160 C CG1   . ILE B 2 343 ? 131.289 137.190 106.729 1.00 23.98  ? 264 ILE A CG1   1 
ATOM   3161 C CG2   . ILE B 2 343 ? 133.593 138.167 106.868 1.00 23.98  ? 264 ILE A CG2   1 
ATOM   3162 C CD1   . ILE B 2 343 ? 130.553 138.359 106.122 1.00 23.98  ? 264 ILE A CD1   1 
ATOM   3163 N N     . ILE B 2 344 ? 135.282 136.017 108.597 1.00 24.31  ? 265 ILE A N     1 
ATOM   3164 C CA    . ILE B 2 344 ? 136.647 136.188 109.075 1.00 24.31  ? 265 ILE A CA    1 
ATOM   3165 C C     . ILE B 2 344 ? 137.396 137.015 108.038 1.00 24.31  ? 265 ILE A C     1 
ATOM   3166 O O     . ILE B 2 344 ? 137.793 136.502 106.987 1.00 24.31  ? 265 ILE A O     1 
ATOM   3167 C CB    . ILE B 2 344 ? 137.333 134.838 109.323 1.00 24.31  ? 265 ILE A CB    1 
ATOM   3168 C CG1   . ILE B 2 344 ? 136.501 133.994 110.289 1.00 24.31  ? 265 ILE A CG1   1 
ATOM   3169 C CG2   . ILE B 2 344 ? 138.728 135.045 109.894 1.00 24.31  ? 265 ILE A CG2   1 
ATOM   3170 C CD1   . ILE B 2 344 ? 137.094 132.635 110.584 1.00 24.31  ? 265 ILE A CD1   1 
ATOM   3171 N N     . LEU B 2 345 ? 137.589 138.296 108.335 1.00 32.08  ? 266 LEU A N     1 
ATOM   3172 C CA    . LEU B 2 345 ? 138.299 139.209 107.451 1.00 32.08  ? 266 LEU A CA    1 
ATOM   3173 C C     . LEU B 2 345 ? 139.776 139.234 107.826 1.00 32.08  ? 266 LEU A C     1 
ATOM   3174 O O     . LEU B 2 345 ? 140.122 139.352 109.006 1.00 32.08  ? 266 LEU A O     1 
ATOM   3175 C CB    . LEU B 2 345 ? 137.692 140.610 107.543 1.00 32.08  ? 266 LEU A CB    1 
ATOM   3176 C CG    . LEU B 2 345 ? 138.434 141.767 106.871 1.00 32.08  ? 266 LEU A CG    1 
ATOM   3177 C CD1   . LEU B 2 345 ? 138.109 141.810 105.389 1.00 32.08  ? 266 LEU A CD1   1 
ATOM   3178 C CD2   . LEU B 2 345 ? 138.075 143.083 107.538 1.00 32.08  ? 266 LEU A CD2   1 
ATOM   3179 N N     . PHE B 2 346 ? 140.641 139.121 106.820 1.00 33.81  ? 267 PHE A N     1 
ATOM   3180 C CA    . PHE B 2 346 ? 142.085 139.081 107.016 1.00 33.81  ? 267 PHE A CA    1 
ATOM   3181 C C     . PHE B 2 346 ? 142.763 140.271 106.356 1.00 33.81  ? 267 PHE A C     1 
ATOM   3182 O O     . PHE B 2 346 ? 142.411 140.658 105.237 1.00 33.81  ? 267 PHE A O     1 
ATOM   3183 C CB    . PHE B 2 346 ? 142.691 137.787 106.462 1.00 33.81  ? 267 PHE A CB    1 
ATOM   3184 C CG    . PHE B 2 346 ? 142.359 136.569 107.265 1.00 33.81  ? 267 PHE A CG    1 
ATOM   3185 C CD1   . PHE B 2 346 ? 143.064 136.289 108.420 1.00 33.81  ? 267 PHE A CD1   1 
ATOM   3186 C CD2   . PHE B 2 346 ? 141.353 135.709 106.876 1.00 33.81  ? 267 PHE A CD2   1 
ATOM   3187 C CE1   . PHE B 2 346 ? 142.775 135.177 109.171 1.00 33.81  ? 267 PHE A CE1   1 
ATOM   3188 C CE2   . PHE B 2 346 ? 141.059 134.590 107.629 1.00 33.81  ? 267 PHE A CE2   1 
ATOM   3189 C CZ    . PHE B 2 346 ? 141.772 134.327 108.776 1.00 33.81  ? 267 PHE A CZ    1 
ATOM   3190 N N     . LEU B 2 347 ? 143.732 140.847 107.069 1.00 48.53  ? 268 LEU A N     1 
ATOM   3191 C CA    . LEU B 2 347 ? 144.784 141.687 106.497 1.00 48.53  ? 268 LEU A CA    1 
ATOM   3192 C C     . LEU B 2 347 ? 146.080 141.015 106.950 1.00 48.53  ? 268 LEU A C     1 
ATOM   3193 O O     . LEU B 2 347 ? 146.661 141.372 107.977 1.00 48.53  ? 268 LEU A O     1 
ATOM   3194 C CB    . LEU B 2 347 ? 144.680 143.138 106.964 1.00 48.53  ? 268 LEU A CB    1 
ATOM   3195 C CG    . LEU B 2 347 ? 143.418 143.901 106.551 1.00 48.53  ? 268 LEU A CG    1 
ATOM   3196 C CD1   . LEU B 2 347 ? 142.245 143.589 107.472 1.00 48.53  ? 268 LEU A CD1   1 
ATOM   3197 C CD2   . LEU B 2 347 ? 143.697 145.396 106.527 1.00 48.53  ? 268 LEU A CD2   1 
ATOM   3198 N N     . ASN B 2 348 ? 146.526 140.029 106.171 1.00 52.85  ? 269 ASN A N     1 
ATOM   3199 C CA    . ASN B 2 348 ? 147.521 139.078 106.660 1.00 52.85  ? 269 ASN A CA    1 
ATOM   3200 C C     . ASN B 2 348 ? 148.937 139.642 106.581 1.00 52.85  ? 269 ASN A C     1 
ATOM   3201 O O     . ASN B 2 348 ? 149.626 139.755 107.601 1.00 52.85  ? 269 ASN A O     1 
ATOM   3202 C CB    . ASN B 2 348 ? 147.414 137.765 105.875 1.00 52.85  ? 269 ASN A CB    1 
ATOM   3203 C CG    . ASN B 2 348 ? 147.431 137.976 104.371 1.00 52.85  ? 269 ASN A CG    1 
ATOM   3204 O OD1   . ASN B 2 348 ? 147.419 139.110 103.892 1.00 52.85  ? 269 ASN A OD1   1 
ATOM   3205 N ND2   . ASN B 2 348 ? 147.461 136.882 103.620 1.00 52.85  ? 269 ASN A ND2   1 
ATOM   3206 N N     . LYS B 2 349 ? 149.390 139.995 105.382 1.00 58.71  ? 270 LYS A N     1 
ATOM   3207 C CA    . LYS B 2 349 ? 150.750 140.489 105.224 1.00 58.71  ? 270 LYS A CA    1 
ATOM   3208 C C     . LYS B 2 349 ? 150.934 141.796 105.987 1.00 58.71  ? 270 LYS A C     1 
ATOM   3209 O O     . LYS B 2 349 ? 150.043 142.648 106.031 1.00 58.71  ? 270 LYS A O     1 
ATOM   3210 C CB    . LYS B 2 349 ? 151.083 140.697 103.745 1.00 58.71  ? 270 LYS A CB    1 
ATOM   3211 C CG    . LYS B 2 349 ? 150.805 139.493 102.854 1.00 58.71  ? 270 LYS A CG    1 
ATOM   3212 C CD    . LYS B 2 349 ? 150.771 139.892 101.387 1.00 58.71  ? 270 LYS A CD    1 
ATOM   3213 C CE    . LYS B 2 349 ? 150.442 138.708 100.491 1.00 58.71  ? 270 LYS A CE    1 
ATOM   3214 N NZ    . LYS B 2 349 ? 148.993 138.365 100.524 1.00 58.71  ? 270 LYS A NZ    1 
ATOM   3215 N N     . LYS B 2 350 ? 152.112 141.947 106.597 1.00 66.38  ? 271 LYS A N     1 
ATOM   3216 C CA    . LYS B 2 350 ? 152.419 143.135 107.384 1.00 66.38  ? 271 LYS A CA    1 
ATOM   3217 C C     . LYS B 2 350 ? 153.831 143.637 107.104 1.00 66.38  ? 271 LYS A C     1 
ATOM   3218 O O     . LYS B 2 350 ? 154.358 144.469 107.851 1.00 66.38  ? 271 LYS A O     1 
ATOM   3219 C CB    . LYS B 2 350 ? 152.248 142.857 108.880 1.00 66.38  ? 271 LYS A CB    1 
ATOM   3220 C CG    . LYS B 2 350 ? 151.988 144.098 109.718 1.00 66.38  ? 271 LYS A CG    1 
ATOM   3221 C CD    . LYS B 2 350 ? 151.999 143.779 111.204 1.00 66.38  ? 271 LYS A CD    1 
ATOM   3222 C CE    . LYS B 2 350 ? 153.364 144.044 111.819 1.00 66.38  ? 271 LYS A CE    1 
ATOM   3223 N NZ    . LYS B 2 350 ? 153.402 143.713 113.270 1.00 66.38  ? 271 LYS A NZ    1 
ATOM   3224 N N     . ASP B 2 351 ? 154.457 143.148 106.032 1.00 68.90  ? 272 ASP A N     1 
ATOM   3225 C CA    . ASP B 2 351 ? 155.786 143.590 105.637 1.00 68.90  ? 272 ASP A CA    1 
ATOM   3226 C C     . ASP B 2 351 ? 155.767 144.566 104.470 1.00 68.90  ? 272 ASP A C     1 
ATOM   3227 O O     . ASP B 2 351 ? 156.784 145.220 104.216 1.00 68.90  ? 272 ASP A O     1 
ATOM   3228 C CB    . ASP B 2 351 ? 156.659 142.381 105.269 1.00 68.90  ? 272 ASP A CB    1 
ATOM   3229 C CG    . ASP B 2 351 ? 156.950 141.488 106.460 1.00 68.90  ? 272 ASP A CG    1 
ATOM   3230 O OD1   . ASP B 2 351 ? 156.730 141.932 107.606 1.00 68.90  ? 272 ASP A OD1   1 
ATOM   3231 O OD2   . ASP B 2 351 ? 157.399 140.342 106.249 1.00 68.90  ? 272 ASP A OD2   1 
ATOM   3232 N N     . LEU B 2 352 ? 154.643 144.679 103.757 1.00 67.81  ? 273 LEU A N     1 
ATOM   3233 C CA    . LEU B 2 352 ? 154.503 145.666 102.695 1.00 67.81  ? 273 LEU A CA    1 
ATOM   3234 C C     . LEU B 2 352 ? 153.324 146.599 102.949 1.00 67.81  ? 273 LEU A C     1 
ATOM   3235 O O     . LEU B 2 352 ? 153.004 147.420 102.080 1.00 67.81  ? 273 LEU A O     1 
ATOM   3236 C CB    . LEU B 2 352 ? 154.337 144.971 101.335 1.00 67.81  ? 273 LEU A CB    1 
ATOM   3237 C CG    . LEU B 2 352 ? 154.540 145.827 100.081 1.00 67.81  ? 273 LEU A CG    1 
ATOM   3238 C CD1   . LEU B 2 352 ? 156.022 146.043 99.817  1.00 67.81  ? 273 LEU A CD1   1 
ATOM   3239 C CD2   . LEU B 2 352 ? 153.866 145.186 98.878  1.00 67.81  ? 273 LEU A CD2   1 
ATOM   3240 N N     . PHE B 2 353 ? 152.673 146.503 104.107 1.00 63.50  ? 274 PHE A N     1 
ATOM   3241 C CA    . PHE B 2 353 ? 151.511 147.322 104.418 1.00 63.50  ? 274 PHE A CA    1 
ATOM   3242 C C     . PHE B 2 353 ? 151.874 148.662 105.045 1.00 63.50  ? 274 PHE A C     1 
ATOM   3243 O O     . PHE B 2 353 ? 150.989 149.507 105.211 1.00 63.50  ? 274 PHE A O     1 
ATOM   3244 C CB    . PHE B 2 353 ? 150.569 146.561 105.363 1.00 63.50  ? 274 PHE A CB    1 
ATOM   3245 C CG    . PHE B 2 353 ? 149.761 145.479 104.689 1.00 63.50  ? 274 PHE A CG    1 
ATOM   3246 C CD1   . PHE B 2 353 ? 150.186 144.901 103.503 1.00 63.50  ? 274 PHE A CD1   1 
ATOM   3247 C CD2   . PHE B 2 353 ? 148.573 145.041 105.250 1.00 63.50  ? 274 PHE A CD2   1 
ATOM   3248 C CE1   . PHE B 2 353 ? 149.441 143.911 102.891 1.00 63.50  ? 274 PHE A CE1   1 
ATOM   3249 C CE2   . PHE B 2 353 ? 147.825 144.051 104.641 1.00 63.50  ? 274 PHE A CE2   1 
ATOM   3250 C CZ    . PHE B 2 353 ? 148.260 143.485 103.461 1.00 63.50  ? 274 PHE A CZ    1 
ATOM   3251 N N     . GLU B 2 354 ? 153.141 148.877 105.393 1.00 71.28  ? 275 GLU A N     1 
ATOM   3252 C CA    . GLU B 2 354 ? 153.592 150.112 106.025 1.00 71.28  ? 275 GLU A CA    1 
ATOM   3253 C C     . GLU B 2 354 ? 154.436 150.986 105.113 1.00 71.28  ? 275 GLU A C     1 
ATOM   3254 O O     . GLU B 2 354 ? 154.283 152.210 105.127 1.00 71.28  ? 275 GLU A O     1 
ATOM   3255 C CB    . GLU B 2 354 ? 154.404 149.791 107.286 1.00 71.28  ? 275 GLU A CB    1 
ATOM   3256 C CG    . GLU B 2 354 ? 153.584 149.201 108.420 1.00 71.28  ? 275 GLU A CG    1 
ATOM   3257 C CD    . GLU B 2 354 ? 153.435 147.695 108.322 1.00 71.28  ? 275 GLU A CD    1 
ATOM   3258 O OE1   . GLU B 2 354 ? 154.040 147.088 107.413 1.00 71.28  ? 275 GLU A OE1   1 
ATOM   3259 O OE2   . GLU B 2 354 ? 152.708 147.117 109.157 1.00 71.28  ? 275 GLU A OE2   1 
ATOM   3260 N N     . GLU B 2 355 ? 155.325 150.388 104.318 1.00 74.24  ? 276 GLU A N     1 
ATOM   3261 C CA    . GLU B 2 355 ? 156.278 151.170 103.540 1.00 74.24  ? 276 GLU A CA    1 
ATOM   3262 C C     . GLU B 2 355 ? 155.602 152.069 102.513 1.00 74.24  ? 276 GLU A C     1 
ATOM   3263 O O     . GLU B 2 355 ? 156.168 153.107 102.152 1.00 74.24  ? 276 GLU A O     1 
ATOM   3264 C CB    . GLU B 2 355 ? 157.264 150.236 102.838 1.00 74.24  ? 276 GLU A CB    1 
ATOM   3265 C CG    . GLU B 2 355 ? 158.396 149.754 103.730 1.00 74.24  ? 276 GLU A CG    1 
ATOM   3266 C CD    . GLU B 2 355 ? 157.929 148.767 104.782 1.00 74.24  ? 276 GLU A CD    1 
ATOM   3267 O OE1   . GLU B 2 355 ? 156.737 148.395 104.761 1.00 74.24  ? 276 GLU A OE1   1 
ATOM   3268 O OE2   . GLU B 2 355 ? 158.753 148.364 105.629 1.00 74.24  ? 276 GLU A OE2   1 
ATOM   3269 N N     . LYS B 2 356 ? 154.413 151.705 102.035 1.00 74.08  ? 277 LYS A N     1 
ATOM   3270 C CA    . LYS B 2 356 ? 153.740 152.457 100.984 1.00 74.08  ? 277 LYS A CA    1 
ATOM   3271 C C     . LYS B 2 356 ? 152.688 153.417 101.524 1.00 74.08  ? 277 LYS A C     1 
ATOM   3272 O O     . LYS B 2 356 ? 151.981 154.051 100.735 1.00 74.08  ? 277 LYS A O     1 
ATOM   3273 C CB    . LYS B 2 356 ? 153.106 151.499 99.971  1.00 74.08  ? 277 LYS A CB    1 
ATOM   3274 C CG    . LYS B 2 356 ? 151.839 150.806 100.454 1.00 74.08  ? 277 LYS A CG    1 
ATOM   3275 C CD    . LYS B 2 356 ? 151.282 149.871 99.391  1.00 74.08  ? 277 LYS A CD    1 
ATOM   3276 C CE    . LYS B 2 356 ? 150.703 150.642 98.213  1.00 74.08  ? 277 LYS A CE    1 
ATOM   3277 N NZ    . LYS B 2 356 ? 150.142 149.743 97.168  1.00 74.08  ? 277 LYS A NZ    1 
ATOM   3278 N N     . ILE B 2 357 ? 152.562 153.541 102.847 1.00 73.62  ? 278 ILE A N     1 
ATOM   3279 C CA    . ILE B 2 357 ? 151.627 154.511 103.406 1.00 73.62  ? 278 ILE A CA    1 
ATOM   3280 C C     . ILE B 2 357 ? 152.189 155.926 103.363 1.00 73.62  ? 278 ILE A C     1 
ATOM   3281 O O     . ILE B 2 357 ? 151.417 156.893 103.391 1.00 73.62  ? 278 ILE A O     1 
ATOM   3282 C CB    . ILE B 2 357 ? 151.252 154.136 104.851 1.00 73.62  ? 278 ILE A CB    1 
ATOM   3283 C CG1   . ILE B 2 357 ? 150.456 152.828 104.866 1.00 73.62  ? 278 ILE A CG1   1 
ATOM   3284 C CG2   . ILE B 2 357 ? 150.451 155.262 105.501 1.00 73.62  ? 278 ILE A CG2   1 
ATOM   3285 C CD1   . ILE B 2 357 ? 150.209 152.266 106.254 1.00 73.62  ? 278 ILE A CD1   1 
ATOM   3286 N N     . LYS B 2 358 ? 153.511 156.076 103.285 1.00 76.76  ? 279 LYS A N     1 
ATOM   3287 C CA    . LYS B 2 358 ? 154.133 157.393 103.275 1.00 76.76  ? 279 LYS A CA    1 
ATOM   3288 C C     . LYS B 2 358 ? 154.034 158.093 101.926 1.00 76.76  ? 279 LYS A C     1 
ATOM   3289 O O     . LYS B 2 358 ? 154.301 159.298 101.856 1.00 76.76  ? 279 LYS A O     1 
ATOM   3290 C CB    . LYS B 2 358 ? 155.606 157.280 103.679 1.00 76.76  ? 279 LYS A CB    1 
ATOM   3291 C CG    . LYS B 2 358 ? 155.848 157.349 105.181 1.00 76.76  ? 279 LYS A CG    1 
ATOM   3292 C CD    . LYS B 2 358 ? 155.493 156.045 105.883 1.00 76.76  ? 279 LYS A CD    1 
ATOM   3293 C CE    . LYS B 2 358 ? 156.526 154.961 105.614 1.00 76.76  ? 279 LYS A CE    1 
ATOM   3294 N NZ    . LYS B 2 358 ? 156.274 153.736 106.423 1.00 76.76  ? 279 LYS A NZ    1 
ATOM   3295 N N     . LYS B 2 359 ? 153.662 157.382 100.859 1.00 78.57  ? 280 LYS A N     1 
ATOM   3296 C CA    . LYS B 2 359 ? 153.567 158.023 99.551  1.00 78.57  ? 280 LYS A CA    1 
ATOM   3297 C C     . LYS B 2 359 ? 152.497 159.107 99.547  1.00 78.57  ? 280 LYS A C     1 
ATOM   3298 O O     . LYS B 2 359 ? 152.682 160.168 98.939  1.00 78.57  ? 280 LYS A O     1 
ATOM   3299 C CB    . LYS B 2 359 ? 153.291 156.977 98.468  1.00 78.57  ? 280 LYS A CB    1 
ATOM   3300 C CG    . LYS B 2 359 ? 151.857 156.451 98.411  1.00 78.57  ? 280 LYS A CG    1 
ATOM   3301 C CD    . LYS B 2 359 ? 151.620 155.626 97.155  1.00 78.57  ? 280 LYS A CD    1 
ATOM   3302 C CE    . LYS B 2 359 ? 152.010 154.171 97.354  1.00 78.57  ? 280 LYS A CE    1 
ATOM   3303 N NZ    . LYS B 2 359 ? 151.484 153.307 96.261  1.00 78.57  ? 280 LYS A NZ    1 
ATOM   3304 N N     . SER B 2 360 ? 151.377 158.861 100.214 1.00 80.60  ? 281 SER A N     1 
ATOM   3305 C CA    . SER B 2 360 ? 150.274 159.809 100.271 1.00 80.60  ? 281 SER A CA    1 
ATOM   3306 C C     . SER B 2 360 ? 149.298 159.339 101.345 1.00 80.60  ? 281 SER A C     1 
ATOM   3307 O O     . SER B 2 360 ? 149.267 158.150 101.674 1.00 80.60  ? 281 SER A O     1 
ATOM   3308 C CB    . SER B 2 360 ? 149.564 159.924 98.912  1.00 80.60  ? 281 SER A CB    1 
ATOM   3309 O OG    . SER B 2 360 ? 148.949 158.699 98.554  1.00 80.60  ? 281 SER A OG    1 
ATOM   3310 N N     . PRO B 2 361 ? 148.499 160.251 101.901 1.00 79.85  ? 282 PRO A N     1 
ATOM   3311 C CA    . PRO B 2 361 ? 147.519 159.840 102.917 1.00 79.85  ? 282 PRO A CA    1 
ATOM   3312 C C     . PRO B 2 361 ? 146.411 158.984 102.328 1.00 79.85  ? 282 PRO A C     1 
ATOM   3313 O O     . PRO B 2 361 ? 146.381 158.739 101.118 1.00 79.85  ? 282 PRO A O     1 
ATOM   3314 C CB    . PRO B 2 361 ? 146.978 161.173 103.452 1.00 79.85  ? 282 PRO A CB    1 
ATOM   3315 C CG    . PRO B 2 361 ? 147.258 162.168 102.384 1.00 79.85  ? 282 PRO A CG    1 
ATOM   3316 C CD    . PRO B 2 361 ? 148.487 161.705 101.667 1.00 79.85  ? 282 PRO A CD    1 
ATOM   3317 N N     . LEU B 2 362 ? 145.494 158.521 103.178 1.00 74.66  ? 283 LEU A N     1 
ATOM   3318 C CA    . LEU B 2 362 ? 144.355 157.720 102.733 1.00 74.66  ? 283 LEU A CA    1 
ATOM   3319 C C     . LEU B 2 362 ? 143.269 158.631 102.156 1.00 74.66  ? 283 LEU A C     1 
ATOM   3320 O O     . LEU B 2 362 ? 142.118 158.644 102.592 1.00 74.66  ? 283 LEU A O     1 
ATOM   3321 C CB    . LEU B 2 362 ? 143.823 156.881 103.888 1.00 74.66  ? 283 LEU A CB    1 
ATOM   3322 C CG    . LEU B 2 362 ? 142.777 155.820 103.536 1.00 74.66  ? 283 LEU A CG    1 
ATOM   3323 C CD1   . LEU B 2 362 ? 143.414 154.659 102.792 1.00 74.66  ? 283 LEU A CD1   1 
ATOM   3324 C CD2   . LEU B 2 362 ? 142.070 155.331 104.790 1.00 74.66  ? 283 LEU A CD2   1 
ATOM   3325 N N     . THR B 2 363 ? 143.666 159.411 101.147 1.00 78.74  ? 284 THR A N     1 
ATOM   3326 C CA    . THR B 2 363 ? 142.758 160.366 100.526 1.00 78.74  ? 284 THR A CA    1 
ATOM   3327 C C     . THR B 2 363 ? 142.878 160.393 99.007  1.00 78.74  ? 284 THR A C     1 
ATOM   3328 O O     . THR B 2 363 ? 142.274 161.267 98.372  1.00 78.74  ? 284 THR A O     1 
ATOM   3329 C CB    . THR B 2 363 ? 142.995 161.778 101.081 1.00 78.74  ? 284 THR A CB    1 
ATOM   3330 O OG1   . THR B 2 363 ? 144.297 162.237 100.698 1.00 78.74  ? 284 THR A OG1   1 
ATOM   3331 C CG2   . THR B 2 363 ? 142.876 161.786 102.600 1.00 78.74  ? 284 THR A CG2   1 
ATOM   3332 N N     . ILE B 2 364 ? 143.633 159.474 98.401  1.00 80.27  ? 285 ILE A N     1 
ATOM   3333 C CA    . ILE B 2 364 ? 143.698 159.423 96.944  1.00 80.27  ? 285 ILE A CA    1 
ATOM   3334 C C     . ILE B 2 364 ? 142.311 159.178 96.370  1.00 80.27  ? 285 ILE A C     1 
ATOM   3335 O O     . ILE B 2 364 ? 141.943 159.736 95.328  1.00 80.27  ? 285 ILE A O     1 
ATOM   3336 C CB    . ILE B 2 364 ? 144.703 158.348 96.486  1.00 80.27  ? 285 ILE A CB    1 
ATOM   3337 C CG1   . ILE B 2 364 ? 144.251 156.954 96.934  1.00 80.27  ? 285 ILE A CG1   1 
ATOM   3338 C CG2   . ILE B 2 364 ? 146.086 158.658 97.026  1.00 80.27  ? 285 ILE A CG2   1 
ATOM   3339 C CD1   . ILE B 2 364 ? 145.290 155.874 96.701  1.00 80.27  ? 285 ILE A CD1   1 
ATOM   3340 N N     . CYS B 2 365 ? 141.522 158.335 97.037  1.00 78.38  ? 286 CYS A N     1 
ATOM   3341 C CA    . CYS B 2 365 ? 140.128 158.142 96.663  1.00 78.38  ? 286 CYS A CA    1 
ATOM   3342 C C     . CYS B 2 365 ? 139.213 158.088 97.881  1.00 78.38  ? 286 CYS A C     1 
ATOM   3343 O O     . CYS B 2 365 ? 138.055 157.673 97.746  1.00 78.38  ? 286 CYS A O     1 
ATOM   3344 C CB    . CYS B 2 365 ? 139.970 156.864 95.831  1.00 78.38  ? 286 CYS A CB    1 
ATOM   3345 S SG    . CYS B 2 365 ? 140.908 156.875 94.285  1.00 78.38  ? 286 CYS A SG    1 
ATOM   3346 N N     . TYR B 2 366 ? 139.689 158.494 99.061  1.00 77.24  ? 287 TYR A N     1 
ATOM   3347 C CA    . TYR B 2 366 ? 138.898 158.506 100.290 1.00 77.24  ? 287 TYR A CA    1 
ATOM   3348 C C     . TYR B 2 366 ? 139.061 159.851 100.996 1.00 77.24  ? 287 TYR A C     1 
ATOM   3349 O O     . TYR B 2 366 ? 139.871 159.986 101.924 1.00 77.24  ? 287 TYR A O     1 
ATOM   3350 C CB    . TYR B 2 366 ? 139.299 157.366 101.220 1.00 77.24  ? 287 TYR A CB    1 
ATOM   3351 C CG    . TYR B 2 366 ? 138.370 157.239 102.394 1.00 77.24  ? 287 TYR A CG    1 
ATOM   3352 C CD1   . TYR B 2 366 ? 137.121 156.649 102.260 1.00 77.24  ? 287 TYR A CD1   1 
ATOM   3353 C CD2   . TYR B 2 366 ? 138.738 157.732 103.631 1.00 77.24  ? 287 TYR A CD2   1 
ATOM   3354 C CE1   . TYR B 2 366 ? 136.272 156.541 103.336 1.00 77.24  ? 287 TYR A CE1   1 
ATOM   3355 C CE2   . TYR B 2 366 ? 137.902 157.632 104.710 1.00 77.24  ? 287 TYR A CE2   1 
ATOM   3356 C CZ    . TYR B 2 366 ? 136.670 157.044 104.558 1.00 77.24  ? 287 TYR A CZ    1 
ATOM   3357 O OH    . TYR B 2 366 ? 135.839 156.952 105.652 1.00 77.24  ? 287 TYR A OH    1 
ATOM   3358 N N     . PRO B 2 367 ? 138.297 160.865 100.588 1.00 80.75  ? 288 PRO A N     1 
ATOM   3359 C CA    . PRO B 2 367 ? 138.449 162.193 101.209 1.00 80.75  ? 288 PRO A CA    1 
ATOM   3360 C C     . PRO B 2 367 ? 138.164 162.217 102.704 1.00 80.75  ? 288 PRO A C     1 
ATOM   3361 O O     . PRO B 2 367 ? 138.756 163.037 103.417 1.00 80.75  ? 288 PRO A O     1 
ATOM   3362 C CB    . PRO B 2 367 ? 137.439 163.057 100.437 1.00 80.75  ? 288 PRO A CB    1 
ATOM   3363 C CG    . PRO B 2 367 ? 137.173 162.306 99.162  1.00 80.75  ? 288 PRO A CG    1 
ATOM   3364 C CD    . PRO B 2 367 ? 137.275 160.864 99.530  1.00 80.75  ? 288 PRO A CD    1 
ATOM   3365 N N     . GLU B 2 368 ? 137.281 161.349 103.202 1.00 80.67  ? 289 GLU A N     1 
ATOM   3366 C CA    . GLU B 2 368 ? 136.745 161.492 104.552 1.00 80.67  ? 289 GLU A CA    1 
ATOM   3367 C C     . GLU B 2 368 ? 137.783 161.298 105.653 1.00 80.67  ? 289 GLU A C     1 
ATOM   3368 O O     . GLU B 2 368 ? 137.583 161.816 106.756 1.00 80.67  ? 289 GLU A O     1 
ATOM   3369 C CB    . GLU B 2 368 ? 135.603 160.496 104.761 1.00 80.67  ? 289 GLU A CB    1 
ATOM   3370 C CG    . GLU B 2 368 ? 134.444 160.666 103.795 1.00 80.67  ? 289 GLU A CG    1 
ATOM   3371 C CD    . GLU B 2 368 ? 133.735 161.994 103.959 1.00 80.67  ? 289 GLU A CD    1 
ATOM   3372 O OE1   . GLU B 2 368 ? 133.877 162.617 105.033 1.00 80.67  ? 289 GLU A OE1   1 
ATOM   3373 O OE2   . GLU B 2 368 ? 133.036 162.415 103.014 1.00 80.67  ? 289 GLU A OE2   1 
ATOM   3374 N N     . TYR B 2 369 ? 138.872 160.577 105.399 1.00 77.49  ? 290 TYR A N     1 
ATOM   3375 C CA    . TYR B 2 369 ? 139.832 160.280 106.455 1.00 77.49  ? 290 TYR A CA    1 
ATOM   3376 C C     . TYR B 2 369 ? 140.598 161.538 106.842 1.00 77.49  ? 290 TYR A C     1 
ATOM   3377 O O     . TYR B 2 369 ? 141.102 162.262 105.978 1.00 77.49  ? 290 TYR A O     1 
ATOM   3378 C CB    . TYR B 2 369 ? 140.807 159.189 106.016 1.00 77.49  ? 290 TYR A CB    1 
ATOM   3379 C CG    . TYR B 2 369 ? 141.830 158.844 107.075 1.00 77.49  ? 290 TYR A CG    1 
ATOM   3380 C CD1   . TYR B 2 369 ? 141.437 158.337 108.306 1.00 77.49  ? 290 TYR A CD1   1 
ATOM   3381 C CD2   . TYR B 2 369 ? 143.188 159.021 106.844 1.00 77.49  ? 290 TYR A CD2   1 
ATOM   3382 C CE1   . TYR B 2 369 ? 142.364 158.019 109.277 1.00 77.49  ? 290 TYR A CE1   1 
ATOM   3383 C CE2   . TYR B 2 369 ? 144.124 158.703 107.810 1.00 77.49  ? 290 TYR A CE2   1 
ATOM   3384 C CZ    . TYR B 2 369 ? 143.706 158.203 109.025 1.00 77.49  ? 290 TYR A CZ    1 
ATOM   3385 O OH    . TYR B 2 369 ? 144.630 157.885 109.993 1.00 77.49  ? 290 TYR A OH    1 
ATOM   3386 N N     . ALA B 2 370 ? 140.687 161.793 108.149 1.00 79.04  ? 291 ALA A N     1 
ATOM   3387 C CA    . ALA B 2 370 ? 141.370 162.967 108.678 1.00 79.04  ? 291 ALA A CA    1 
ATOM   3388 C C     . ALA B 2 370 ? 142.255 162.601 109.864 1.00 79.04  ? 291 ALA A C     1 
ATOM   3389 O O     . ALA B 2 370 ? 142.540 163.447 110.716 1.00 79.04  ? 291 ALA A O     1 
ATOM   3390 C CB    . ALA B 2 370 ? 140.363 164.045 109.076 1.00 79.04  ? 291 ALA A CB    1 
ATOM   3391 N N     . GLY B 2 371 ? 142.698 161.346 109.934 1.00 77.88  ? 292 GLY A N     1 
ATOM   3392 C CA    . GLY B 2 371 ? 143.533 160.883 111.020 1.00 77.88  ? 292 GLY A CA    1 
ATOM   3393 C C     . GLY B 2 371 ? 145.011 160.877 110.656 1.00 77.88  ? 292 GLY A C     1 
ATOM   3394 O O     . GLY B 2 371 ? 145.411 161.190 109.538 1.00 77.88  ? 292 GLY A O     1 
ATOM   3395 N N     . SER B 2 372 ? 145.826 160.507 111.642 1.00 78.00  ? 293 SER A N     1 
ATOM   3396 C CA    . SER B 2 372 ? 147.267 160.437 111.439 1.00 78.00  ? 293 SER A CA    1 
ATOM   3397 C C     . SER B 2 372 ? 147.597 159.456 110.322 1.00 78.00  ? 293 SER A C     1 
ATOM   3398 O O     . SER B 2 372 ? 147.062 158.345 110.276 1.00 78.00  ? 293 SER A O     1 
ATOM   3399 C CB    . SER B 2 372 ? 147.961 160.018 112.734 1.00 78.00  ? 293 SER A CB    1 
ATOM   3400 O OG    . SER B 2 372 ? 149.370 160.060 112.594 1.00 78.00  ? 293 SER A OG    1 
ATOM   3401 N N     . ASN B 2 373 ? 148.487 159.869 109.422 1.00 77.23  ? 294 ASN A N     1 
ATOM   3402 C CA    . ASN B 2 373 ? 148.858 159.050 108.268 1.00 77.23  ? 294 ASN A CA    1 
ATOM   3403 C C     . ASN B 2 373 ? 149.971 158.067 108.639 1.00 77.23  ? 294 ASN A C     1 
ATOM   3404 O O     . ASN B 2 373 ? 151.030 158.006 108.016 1.00 77.23  ? 294 ASN A O     1 
ATOM   3405 C CB    . ASN B 2 373 ? 149.271 159.941 107.101 1.00 77.23  ? 294 ASN A CB    1 
ATOM   3406 C CG    . ASN B 2 373 ? 150.450 160.834 107.436 1.00 77.23  ? 294 ASN A CG    1 
ATOM   3407 O OD1   . ASN B 2 373 ? 150.995 160.777 108.538 1.00 77.23  ? 294 ASN A OD1   1 
ATOM   3408 N ND2   . ASN B 2 373 ? 150.852 161.664 106.480 1.00 77.23  ? 294 ASN A ND2   1 
ATOM   3409 N N     . THR B 2 374 ? 149.705 157.285 109.682 1.00 74.59  ? 295 THR A N     1 
ATOM   3410 C CA    . THR B 2 374 ? 150.602 156.233 110.127 1.00 74.59  ? 295 THR A CA    1 
ATOM   3411 C C     . THR B 2 374 ? 149.957 154.871 109.878 1.00 74.59  ? 295 THR A C     1 
ATOM   3412 O O     . THR B 2 374 ? 148.822 154.766 109.407 1.00 74.59  ? 295 THR A O     1 
ATOM   3413 C CB    . THR B 2 374 ? 150.956 156.413 111.605 1.00 74.59  ? 295 THR A CB    1 
ATOM   3414 O OG1   . THR B 2 374 ? 149.764 156.348 112.398 1.00 74.59  ? 295 THR A OG1   1 
ATOM   3415 C CG2   . THR B 2 374 ? 151.643 157.752 111.831 1.00 74.59  ? 295 THR A CG2   1 
ATOM   3416 N N     . TYR B 2 375 ? 150.696 153.811 110.204 1.00 69.89  ? 296 TYR A N     1 
ATOM   3417 C CA    . TYR B 2 375 ? 150.199 152.460 109.962 1.00 69.89  ? 296 TYR A CA    1 
ATOM   3418 C C     . TYR B 2 375 ? 149.025 152.132 110.876 1.00 69.89  ? 296 TYR A C     1 
ATOM   3419 O O     . TYR B 2 375 ? 147.920 151.834 110.408 1.00 69.89  ? 296 TYR A O     1 
ATOM   3420 C CB    . TYR B 2 375 ? 151.324 151.443 110.156 1.00 69.89  ? 296 TYR A CB    1 
ATOM   3421 C CG    . TYR B 2 375 ? 150.824 150.032 110.365 1.00 69.89  ? 296 TYR A CG    1 
ATOM   3422 C CD1   . TYR B 2 375 ? 150.121 149.368 109.369 1.00 69.89  ? 296 TYR A CD1   1 
ATOM   3423 C CD2   . TYR B 2 375 ? 151.051 149.365 111.561 1.00 69.89  ? 296 TYR A CD2   1 
ATOM   3424 C CE1   . TYR B 2 375 ? 149.661 148.078 109.557 1.00 69.89  ? 296 TYR A CE1   1 
ATOM   3425 C CE2   . TYR B 2 375 ? 150.595 148.076 111.758 1.00 69.89  ? 296 TYR A CE2   1 
ATOM   3426 C CZ    . TYR B 2 375 ? 149.901 147.437 110.753 1.00 69.89  ? 296 TYR A CZ    1 
ATOM   3427 O OH    . TYR B 2 375 ? 149.445 146.153 110.947 1.00 69.89  ? 296 TYR A OH    1 
ATOM   3428 N N     . GLU B 2 376 ? 149.248 152.184 112.191 1.00 71.01  ? 297 GLU A N     1 
ATOM   3429 C CA    . GLU B 2 376 ? 148.227 151.726 113.128 1.00 71.01  ? 297 GLU A CA    1 
ATOM   3430 C C     . GLU B 2 376 ? 146.947 152.540 112.995 1.00 71.01  ? 297 GLU A C     1 
ATOM   3431 O O     . GLU B 2 376 ? 145.847 151.978 112.975 1.00 71.01  ? 297 GLU A O     1 
ATOM   3432 C CB    . GLU B 2 376 ? 148.763 151.795 114.557 1.00 71.01  ? 297 GLU A CB    1 
ATOM   3433 C CG    . GLU B 2 376 ? 147.916 151.044 115.577 1.00 71.01  ? 297 GLU A CG    1 
ATOM   3434 C CD    . GLU B 2 376 ? 146.787 151.884 116.145 1.00 71.01  ? 297 GLU A CD    1 
ATOM   3435 O OE1   . GLU B 2 376 ? 146.939 153.121 116.222 1.00 71.01  ? 297 GLU A OE1   1 
ATOM   3436 O OE2   . GLU B 2 376 ? 145.745 151.304 116.518 1.00 71.01  ? 297 GLU A OE2   1 
ATOM   3437 N N     . GLU B 2 377 ? 147.067 153.864 112.893 1.00 72.99  ? 298 GLU A N     1 
ATOM   3438 C CA    . GLU B 2 377 ? 145.877 154.705 112.823 1.00 72.99  ? 298 GLU A CA    1 
ATOM   3439 C C     . GLU B 2 377 ? 145.071 154.418 111.560 1.00 72.99  ? 298 GLU A C     1 
ATOM   3440 O O     . GLU B 2 377 ? 143.869 154.133 111.629 1.00 72.99  ? 298 GLU A O     1 
ATOM   3441 C CB    . GLU B 2 377 ? 146.279 156.179 112.881 1.00 72.99  ? 298 GLU A CB    1 
ATOM   3442 C CG    . GLU B 2 377 ? 145.135 157.125 113.206 1.00 72.99  ? 298 GLU A CG    1 
ATOM   3443 C CD    . GLU B 2 377 ? 144.726 157.069 114.666 1.00 72.99  ? 298 GLU A CD    1 
ATOM   3444 O OE1   . GLU B 2 377 ? 145.572 156.703 115.509 1.00 72.99  ? 298 GLU A OE1   1 
ATOM   3445 O OE2   . GLU B 2 377 ? 143.559 157.392 114.970 1.00 72.99  ? 298 GLU A OE2   1 
ATOM   3446 N N     . ALA B 2 378 ? 145.721 154.472 110.395 1.00 68.97  ? 299 ALA A N     1 
ATOM   3447 C CA    . ALA B 2 378 ? 145.007 154.258 109.141 1.00 68.97  ? 299 ALA A CA    1 
ATOM   3448 C C     . ALA B 2 378 ? 144.505 152.827 109.017 1.00 68.97  ? 299 ALA A C     1 
ATOM   3449 O O     . ALA B 2 378 ? 143.387 152.601 108.537 1.00 68.97  ? 299 ALA A O     1 
ATOM   3450 C CB    . ALA B 2 378 ? 145.908 154.604 107.957 1.00 68.97  ? 299 ALA A CB    1 
ATOM   3451 N N     . ALA B 2 379 ? 145.314 151.851 109.430 1.00 62.95  ? 300 ALA A N     1 
ATOM   3452 C CA    . ALA B 2 379 ? 144.889 150.458 109.356 1.00 62.95  ? 300 ALA A CA    1 
ATOM   3453 C C     . ALA B 2 379 ? 143.681 150.211 110.251 1.00 62.95  ? 300 ALA A C     1 
ATOM   3454 O O     . ALA B 2 379 ? 142.724 149.537 109.853 1.00 62.95  ? 300 ALA A O     1 
ATOM   3455 C CB    . ALA B 2 379 ? 146.049 149.540 109.739 1.00 62.95  ? 300 ALA A CB    1 
ATOM   3456 N N     . ALA B 2 380 ? 143.708 150.754 111.471 1.00 63.25  ? 301 ALA A N     1 
ATOM   3457 C CA    . ALA B 2 380 ? 142.566 150.618 112.368 1.00 63.25  ? 301 ALA A CA    1 
ATOM   3458 C C     . ALA B 2 380 ? 141.336 151.306 111.795 1.00 63.25  ? 301 ALA A C     1 
ATOM   3459 O O     . ALA B 2 380 ? 140.218 150.792 111.909 1.00 63.25  ? 301 ALA A O     1 
ATOM   3460 C CB    . ALA B 2 380 ? 142.908 151.191 113.742 1.00 63.25  ? 301 ALA A CB    1 
ATOM   3461 N N     . TYR B 2 381 ? 141.519 152.477 111.182 1.00 66.21  ? 302 TYR A N     1 
ATOM   3462 C CA    . TYR B 2 381 ? 140.388 153.167 110.574 1.00 66.21  ? 302 TYR A CA    1 
ATOM   3463 C C     . TYR B 2 381 ? 139.773 152.334 109.457 1.00 66.21  ? 302 TYR A C     1 
ATOM   3464 O O     . TYR B 2 381 ? 138.546 152.229 109.352 1.00 66.21  ? 302 TYR A O     1 
ATOM   3465 C CB    . TYR B 2 381 ? 140.832 154.529 110.045 1.00 66.21  ? 302 TYR A CB    1 
ATOM   3466 C CG    . TYR B 2 381 ? 139.697 155.375 109.522 1.00 66.21  ? 302 TYR A CG    1 
ATOM   3467 C CD1   . TYR B 2 381 ? 138.940 156.161 110.378 1.00 66.21  ? 302 TYR A CD1   1 
ATOM   3468 C CD2   . TYR B 2 381 ? 139.387 155.392 108.170 1.00 66.21  ? 302 TYR A CD2   1 
ATOM   3469 C CE1   . TYR B 2 381 ? 137.902 156.936 109.903 1.00 66.21  ? 302 TYR A CE1   1 
ATOM   3470 C CE2   . TYR B 2 381 ? 138.353 156.163 107.687 1.00 66.21  ? 302 TYR A CE2   1 
ATOM   3471 C CZ    . TYR B 2 381 ? 137.613 156.934 108.556 1.00 66.21  ? 302 TYR A CZ    1 
ATOM   3472 O OH    . TYR B 2 381 ? 136.580 157.706 108.078 1.00 66.21  ? 302 TYR A OH    1 
ATOM   3473 N N     . ILE B 2 382 ? 140.612 151.731 108.614 1.00 58.60  ? 303 ILE A N     1 
ATOM   3474 C CA    . ILE B 2 382 ? 140.101 150.902 107.528 1.00 58.60  ? 303 ILE A CA    1 
ATOM   3475 C C     . ILE B 2 382 ? 139.393 149.671 108.082 1.00 58.60  ? 303 ILE A C     1 
ATOM   3476 O O     . ILE B 2 382 ? 138.339 149.264 107.577 1.00 58.60  ? 303 ILE A O     1 
ATOM   3477 C CB    . ILE B 2 382 ? 141.243 150.521 106.570 1.00 58.60  ? 303 ILE A CB    1 
ATOM   3478 C CG1   . ILE B 2 382 ? 141.693 151.754 105.784 1.00 58.60  ? 303 ILE A CG1   1 
ATOM   3479 C CG2   . ILE B 2 382 ? 140.793 149.419 105.627 1.00 58.60  ? 303 ILE A CG2   1 
ATOM   3480 C CD1   . ILE B 2 382 ? 143.007 151.581 105.072 1.00 58.60  ? 303 ILE A CD1   1 
ATOM   3481 N N     . GLN B 2 383 ? 139.961 149.054 109.120 1.00 51.83  ? 304 GLN A N     1 
ATOM   3482 C CA    . GLN B 2 383 ? 139.310 147.915 109.759 1.00 51.83  ? 304 GLN A CA    1 
ATOM   3483 C C     . GLN B 2 383 ? 137.932 148.300 110.280 1.00 51.83  ? 304 GLN A C     1 
ATOM   3484 O O     . GLN B 2 383 ? 136.946 147.589 110.057 1.00 51.83  ? 304 GLN A O     1 
ATOM   3485 C CB    . GLN B 2 383 ? 140.195 147.391 110.894 1.00 51.83  ? 304 GLN A CB    1 
ATOM   3486 C CG    . GLN B 2 383 ? 139.482 146.560 111.958 1.00 51.83  ? 304 GLN A CG    1 
ATOM   3487 C CD    . GLN B 2 383 ? 140.358 146.303 113.167 1.00 51.83  ? 304 GLN A CD    1 
ATOM   3488 O OE1   . GLN B 2 383 ? 139.880 145.867 114.213 1.00 51.83  ? 304 GLN A OE1   1 
ATOM   3489 N NE2   . GLN B 2 383 ? 141.652 146.556 113.023 1.00 51.83  ? 304 GLN A NE2   1 
ATOM   3490 N N     . CYS B 2 384 ? 137.849 149.428 110.984 1.00 56.18  ? 305 CYS A N     1 
ATOM   3491 C CA    . CYS B 2 384 ? 136.570 149.862 111.534 1.00 56.18  ? 305 CYS A CA    1 
ATOM   3492 C C     . CYS B 2 384 ? 135.575 150.170 110.423 1.00 56.18  ? 305 CYS A C     1 
ATOM   3493 O O     . CYS B 2 384 ? 134.384 149.852 110.541 1.00 56.18  ? 305 CYS A O     1 
ATOM   3494 C CB    . CYS B 2 384 ? 136.778 151.082 112.431 1.00 56.18  ? 305 CYS A CB    1 
ATOM   3495 S SG    . CYS B 2 384 ? 137.601 150.711 114.001 1.00 56.18  ? 305 CYS A SG    1 
ATOM   3496 N N     . GLN B 2 385 ? 136.040 150.782 109.333 1.00 54.76  ? 306 GLN A N     1 
ATOM   3497 C CA    . GLN B 2 385 ? 135.136 151.071 108.233 1.00 54.76  ? 306 GLN A CA    1 
ATOM   3498 C C     . GLN B 2 385 ? 134.644 149.817 107.527 1.00 54.76  ? 306 GLN A C     1 
ATOM   3499 O O     . GLN B 2 385 ? 133.488 149.793 107.101 1.00 54.76  ? 306 GLN A O     1 
ATOM   3500 C CB    . GLN B 2 385 ? 135.797 152.002 107.226 1.00 54.76  ? 306 GLN A CB    1 
ATOM   3501 C CG    . GLN B 2 385 ? 135.830 153.437 107.688 1.00 54.76  ? 306 GLN A CG    1 
ATOM   3502 C CD    . GLN B 2 385 ? 134.667 154.236 107.139 1.00 54.76  ? 306 GLN A CD    1 
ATOM   3503 O OE1   . GLN B 2 385 ? 134.854 155.105 106.288 1.00 54.76  ? 306 GLN A OE1   1 
ATOM   3504 N NE2   . GLN B 2 385 ? 133.471 153.967 107.629 1.00 54.76  ? 306 GLN A NE2   1 
ATOM   3505 N N     . PHE B 2 386 ? 135.472 148.781 107.390 1.00 47.24  ? 307 PHE A N     1 
ATOM   3506 C CA    . PHE B 2 386 ? 134.960 147.498 106.914 1.00 47.24  ? 307 PHE A CA    1 
ATOM   3507 C C     . PHE B 2 386 ? 133.975 146.878 107.895 1.00 47.24  ? 307 PHE A C     1 
ATOM   3508 O O     . PHE B 2 386 ? 132.966 146.303 107.476 1.00 47.24  ? 307 PHE A O     1 
ATOM   3509 C CB    . PHE B 2 386 ? 136.107 146.521 106.637 1.00 47.24  ? 307 PHE A CB    1 
ATOM   3510 C CG    . PHE B 2 386 ? 136.775 146.728 105.304 1.00 47.24  ? 307 PHE A CG    1 
ATOM   3511 C CD1   . PHE B 2 386 ? 136.217 146.190 104.156 1.00 47.24  ? 307 PHE A CD1   1 
ATOM   3512 C CD2   . PHE B 2 386 ? 137.950 147.449 105.194 1.00 47.24  ? 307 PHE A CD2   1 
ATOM   3513 C CE1   . PHE B 2 386 ? 136.819 146.365 102.928 1.00 47.24  ? 307 PHE A CE1   1 
ATOM   3514 C CE2   . PHE B 2 386 ? 138.555 147.628 103.964 1.00 47.24  ? 307 PHE A CE2   1 
ATOM   3515 C CZ    . PHE B 2 386 ? 137.987 147.085 102.831 1.00 47.24  ? 307 PHE A CZ    1 
ATOM   3516 N N     . GLU B 2 387 ? 134.245 146.990 109.197 1.00 46.01  ? 308 GLU A N     1 
ATOM   3517 C CA    . GLU B 2 387 ? 133.294 146.501 110.190 1.00 46.01  ? 308 GLU A CA    1 
ATOM   3518 C C     . GLU B 2 387 ? 131.948 147.200 110.049 1.00 46.01  ? 308 GLU A C     1 
ATOM   3519 O O     . GLU B 2 387 ? 130.895 146.588 110.261 1.00 46.01  ? 308 GLU A O     1 
ATOM   3520 C CB    . GLU B 2 387 ? 133.845 146.719 111.599 1.00 46.01  ? 308 GLU A CB    1 
ATOM   3521 C CG    . GLU B 2 387 ? 135.079 145.908 111.941 1.00 46.01  ? 308 GLU A CG    1 
ATOM   3522 C CD    . GLU B 2 387 ? 134.797 144.430 112.004 1.00 46.01  ? 308 GLU A CD    1 
ATOM   3523 O OE1   . GLU B 2 387 ? 133.664 144.066 112.378 1.00 46.01  ? 308 GLU A OE1   1 
ATOM   3524 O OE2   . GLU B 2 387 ? 135.707 143.635 111.690 1.00 46.01  ? 308 GLU A OE2   1 
ATOM   3525 N N     . ASP B 2 388 ? 131.967 148.485 109.693 1.00 47.78  ? 309 ASP A N     1 
ATOM   3526 C CA    . ASP B 2 388 ? 130.741 149.276 109.679 1.00 47.78  ? 309 ASP A CA    1 
ATOM   3527 C C     . ASP B 2 388 ? 129.719 148.776 108.663 1.00 47.78  ? 309 ASP A C     1 
ATOM   3528 O O     . ASP B 2 388 ? 128.529 149.068 108.816 1.00 47.78  ? 309 ASP A O     1 
ATOM   3529 C CB    . ASP B 2 388 ? 131.069 150.743 109.397 1.00 47.78  ? 309 ASP A CB    1 
ATOM   3530 C CG    . ASP B 2 388 ? 129.877 151.657 109.608 1.00 47.78  ? 309 ASP A CG    1 
ATOM   3531 O OD1   . ASP B 2 388 ? 129.479 151.858 110.776 1.00 47.78  ? 309 ASP A OD1   1 
ATOM   3532 O OD2   . ASP B 2 388 ? 129.336 152.175 108.609 1.00 47.78  ? 309 ASP A OD2   1 
ATOM   3533 N N     . LEU B 2 389 ? 130.142 148.036 107.634 1.00 42.43  ? 310 LEU A N     1 
ATOM   3534 C CA    . LEU B 2 389 ? 129.189 147.574 106.628 1.00 42.43  ? 310 LEU A CA    1 
ATOM   3535 C C     . LEU B 2 389 ? 128.296 146.453 107.139 1.00 42.43  ? 310 LEU A C     1 
ATOM   3536 O O     . LEU B 2 389 ? 127.317 146.109 106.468 1.00 42.43  ? 310 LEU A O     1 
ATOM   3537 C CB    . LEU B 2 389 ? 129.910 147.110 105.360 1.00 42.43  ? 310 LEU A CB    1 
ATOM   3538 C CG    . LEU B 2 389 ? 130.585 148.200 104.525 1.00 42.43  ? 310 LEU A CG    1 
ATOM   3539 C CD1   . LEU B 2 389 ? 131.956 148.511 105.062 1.00 42.43  ? 310 LEU A CD1   1 
ATOM   3540 C CD2   . LEU B 2 389 ? 130.661 147.803 103.063 1.00 42.43  ? 310 LEU A CD2   1 
ATOM   3541 N N     . ASN B 2 390 ? 128.602 145.871 108.297 1.00 36.40  ? 311 ASN A N     1 
ATOM   3542 C CA    . ASN B 2 390 ? 127.726 144.859 108.869 1.00 36.40  ? 311 ASN A CA    1 
ATOM   3543 C C     . ASN B 2 390 ? 126.398 145.509 109.235 1.00 36.40  ? 311 ASN A C     1 
ATOM   3544 O O     . ASN B 2 390 ? 126.309 146.241 110.225 1.00 36.40  ? 311 ASN A O     1 
ATOM   3545 C CB    . ASN B 2 390 ? 128.377 144.209 110.091 1.00 36.40  ? 311 ASN A CB    1 
ATOM   3546 C CG    . ASN B 2 390 ? 127.599 143.017 110.605 1.00 36.40  ? 311 ASN A CG    1 
ATOM   3547 O OD1   . ASN B 2 390 ? 126.540 142.679 110.080 1.00 36.40  ? 311 ASN A OD1   1 
ATOM   3548 N ND2   . ASN B 2 390 ? 128.125 142.367 111.636 1.00 36.40  ? 311 ASN A ND2   1 
ATOM   3549 N N     . LYS B 2 391 ? 125.359 145.243 108.441 1.00 41.45  ? 312 LYS A N     1 
ATOM   3550 C CA    . LYS B 2 391 ? 124.100 145.967 108.561 1.00 41.45  ? 312 LYS A CA    1 
ATOM   3551 C C     . LYS B 2 391 ? 123.207 145.440 109.675 1.00 41.45  ? 312 LYS A C     1 
ATOM   3552 O O     . LYS B 2 391 ? 122.251 146.127 110.053 1.00 41.45  ? 312 LYS A O     1 
ATOM   3553 C CB    . LYS B 2 391 ? 123.349 145.916 107.230 1.00 41.45  ? 312 LYS A CB    1 
ATOM   3554 C CG    . LYS B 2 391 ? 123.954 146.814 106.164 1.00 41.45  ? 312 LYS A CG    1 
ATOM   3555 C CD    . LYS B 2 391 ? 123.080 146.896 104.926 1.00 41.45  ? 312 LYS A CD    1 
ATOM   3556 C CE    . LYS B 2 391 ? 123.629 147.907 103.934 1.00 41.45  ? 312 LYS A CE    1 
ATOM   3557 N NZ    . LYS B 2 391 ? 124.988 147.533 103.451 1.00 41.45  ? 312 LYS A NZ    1 
ATOM   3558 N N     . ARG B 2 392 ? 123.485 144.253 110.209 1.00 41.30  ? 313 ARG A N     1 
ATOM   3559 C CA    . ARG B 2 392 ? 122.758 143.728 111.365 1.00 41.30  ? 313 ARG A CA    1 
ATOM   3560 C C     . ARG B 2 392 ? 123.748 142.924 112.202 1.00 41.30  ? 313 ARG A C     1 
ATOM   3561 O O     . ARG B 2 392 ? 124.037 141.764 111.895 1.00 41.30  ? 313 ARG A O     1 
ATOM   3562 C CB    . ARG B 2 392 ? 121.559 142.882 110.947 1.00 41.30  ? 313 ARG A CB    1 
ATOM   3563 C CG    . ARG B 2 392 ? 121.861 141.782 109.942 1.00 41.30  ? 313 ARG A CG    1 
ATOM   3564 C CD    . ARG B 2 392 ? 120.627 141.449 109.113 1.00 41.30  ? 313 ARG A CD    1 
ATOM   3565 N NE    . ARG B 2 392 ? 120.296 142.502 108.160 1.00 41.30  ? 313 ARG A NE    1 
ATOM   3566 C CZ    . ARG B 2 392 ? 120.922 142.696 107.007 1.00 41.30  ? 313 ARG A CZ    1 
ATOM   3567 N NH1   . ARG B 2 392 ? 121.922 141.920 106.623 1.00 41.30  ? 313 ARG A NH1   1 
ATOM   3568 N NH2   . ARG B 2 392 ? 120.533 143.693 106.218 1.00 41.30  ? 313 ARG A NH2   1 
ATOM   3569 N N     . LYS B 2 393 ? 124.263 143.550 113.257 1.00 41.50  ? 314 LYS A N     1 
ATOM   3570 C CA    . LYS B 2 393 ? 125.219 142.923 114.158 1.00 41.50  ? 314 LYS A CA    1 
ATOM   3571 C C     . LYS B 2 393 ? 124.553 142.016 115.184 1.00 41.50  ? 314 LYS A C     1 
ATOM   3572 O O     . LYS B 2 393 ? 125.244 141.474 116.053 1.00 41.50  ? 314 LYS A O     1 
ATOM   3573 C CB    . LYS B 2 393 ? 126.037 143.999 114.878 1.00 41.50  ? 314 LYS A CB    1 
ATOM   3574 C CG    . LYS B 2 393 ? 126.743 144.970 113.943 1.00 41.50  ? 314 LYS A CG    1 
ATOM   3575 C CD    . LYS B 2 393 ? 127.325 146.150 114.702 1.00 41.50  ? 314 LYS A CD    1 
ATOM   3576 C CE    . LYS B 2 393 ? 128.241 146.982 113.820 1.00 41.50  ? 314 LYS A CE    1 
ATOM   3577 N NZ    . LYS B 2 393 ? 127.496 147.677 112.736 1.00 41.50  ? 314 LYS A NZ    1 
ATOM   3578 N N     . ASP B 2 394 ? 123.232 141.844 115.106 1.00 43.43  ? 315 ASP A N     1 
ATOM   3579 C CA    . ASP B 2 394 ? 122.521 141.044 116.096 1.00 43.43  ? 315 ASP A CA    1 
ATOM   3580 C C     . ASP B 2 394 ? 122.741 139.551 115.885 1.00 43.43  ? 315 ASP A C     1 
ATOM   3581 O O     . ASP B 2 394 ? 122.864 138.798 116.857 1.00 43.43  ? 315 ASP A O     1 
ATOM   3582 C CB    . ASP B 2 394 ? 121.027 141.368 116.048 1.00 43.43  ? 315 ASP A CB    1 
ATOM   3583 C CG    . ASP B 2 394 ? 120.719 142.774 116.524 1.00 43.43  ? 315 ASP A CG    1 
ATOM   3584 O OD1   . ASP B 2 394 ? 121.596 143.394 117.161 1.00 43.43  ? 315 ASP A OD1   1 
ATOM   3585 O OD2   . ASP B 2 394 ? 119.599 143.259 116.261 1.00 43.43  ? 315 ASP A OD2   1 
ATOM   3586 N N     . THR B 2 395 ? 122.795 139.104 114.630 1.00 36.78  ? 316 THR A N     1 
ATOM   3587 C CA    . THR B 2 395 ? 122.849 137.682 114.310 1.00 36.78  ? 316 THR A CA    1 
ATOM   3588 C C     . THR B 2 395 ? 124.266 137.177 114.070 1.00 36.78  ? 316 THR A C     1 
ATOM   3589 O O     . THR B 2 395 ? 124.646 136.131 114.605 1.00 36.78  ? 316 THR A O     1 
ATOM   3590 C CB    . THR B 2 395 ? 121.985 137.390 113.076 1.00 36.78  ? 316 THR A CB    1 
ATOM   3591 O OG1   . THR B 2 395 ? 122.450 138.167 111.966 1.00 36.78  ? 316 THR A OG1   1 
ATOM   3592 C CG2   . THR B 2 395 ? 120.527 137.721 113.352 1.00 36.78  ? 316 THR A CG2   1 
ATOM   3593 N N     . LYS B 2 396 ? 125.056 137.891 113.276 1.00 29.61  ? 317 LYS A N     1 
ATOM   3594 C CA    . LYS B 2 396 ? 126.381 137.445 112.873 1.00 29.61  ? 317 LYS A CA    1 
ATOM   3595 C C     . LYS B 2 396 ? 127.453 138.358 113.454 1.00 29.61  ? 317 LYS A C     1 
ATOM   3596 O O     . LYS B 2 396 ? 127.171 139.428 114.000 1.00 29.61  ? 317 LYS A O     1 
ATOM   3597 C CB    . LYS B 2 396 ? 126.488 137.395 111.345 1.00 29.61  ? 317 LYS A CB    1 
ATOM   3598 C CG    . LYS B 2 396 ? 126.191 138.715 110.657 1.00 29.61  ? 317 LYS A CG    1 
ATOM   3599 C CD    . LYS B 2 396 ? 126.207 138.573 109.143 1.00 29.61  ? 317 LYS A CD    1 
ATOM   3600 C CE    . LYS B 2 396 ? 127.592 138.245 108.618 1.00 29.61  ? 317 LYS A CE    1 
ATOM   3601 N NZ    . LYS B 2 396 ? 128.620 139.213 109.081 1.00 29.61  ? 317 LYS A NZ    1 
ATOM   3602 N N     . GLU B 2 397 ? 128.703 137.916 113.323 1.00 26.81  ? 318 GLU A N     1 
ATOM   3603 C CA    . GLU B 2 397 ? 129.844 138.619 113.888 1.00 26.81  ? 318 GLU A CA    1 
ATOM   3604 C C     . GLU B 2 397 ? 130.977 138.635 112.871 1.00 26.81  ? 318 GLU A C     1 
ATOM   3605 O O     . GLU B 2 397 ? 131.028 137.813 111.954 1.00 26.81  ? 318 GLU A O     1 
ATOM   3606 C CB    . GLU B 2 397 ? 130.300 137.965 115.199 1.00 26.81  ? 318 GLU A CB    1 
ATOM   3607 C CG    . GLU B 2 397 ? 131.574 138.547 115.788 1.00 26.81  ? 318 GLU A CG    1 
ATOM   3608 C CD    . GLU B 2 397 ? 131.789 138.139 117.232 1.00 26.81  ? 318 GLU A CD    1 
ATOM   3609 O OE1   . GLU B 2 397 ? 131.024 137.288 117.732 1.00 26.81  ? 318 GLU A OE1   1 
ATOM   3610 O OE2   . GLU B 2 397 ? 132.725 138.669 117.866 1.00 26.81  ? 318 GLU A OE2   1 
ATOM   3611 N N     . ILE B 2 398 ? 131.886 139.593 113.042 1.00 27.34  ? 319 ILE A N     1 
ATOM   3612 C CA    . ILE B 2 398 ? 133.044 139.765 112.173 1.00 27.34  ? 319 ILE A CA    1 
ATOM   3613 C C     . ILE B 2 398 ? 134.304 139.597 113.010 1.00 27.34  ? 319 ILE A C     1 
ATOM   3614 O O     . ILE B 2 398 ? 134.448 140.229 114.063 1.00 27.34  ? 319 ILE A O     1 
ATOM   3615 C CB    . ILE B 2 398 ? 133.039 141.145 111.486 1.00 27.34  ? 319 ILE A CB    1 
ATOM   3616 C CG1   . ILE B 2 398 ? 131.702 141.410 110.787 1.00 27.34  ? 319 ILE A CG1   1 
ATOM   3617 C CG2   . ILE B 2 398 ? 134.200 141.258 110.507 1.00 27.34  ? 319 ILE A CG2   1 
ATOM   3618 C CD1   . ILE B 2 398 ? 131.390 140.465 109.654 1.00 27.34  ? 319 ILE A CD1   1 
ATOM   3619 N N     . TYR B 2 399 ? 135.216 138.747 112.542 1.00 24.63  ? 320 TYR A N     1 
ATOM   3620 C CA    . TYR B 2 399 ? 136.498 138.519 113.204 1.00 24.63  ? 320 TYR A CA    1 
ATOM   3621 C C     . TYR B 2 399 ? 137.601 139.039 112.291 1.00 24.63  ? 320 TYR A C     1 
ATOM   3622 O O     . TYR B 2 399 ? 137.788 138.524 111.186 1.00 24.63  ? 320 TYR A O     1 
ATOM   3623 C CB    . TYR B 2 399 ? 136.702 137.037 113.522 1.00 24.63  ? 320 TYR A CB    1 
ATOM   3624 C CG    . TYR B 2 399 ? 135.568 136.408 114.301 1.00 24.63  ? 320 TYR A CG    1 
ATOM   3625 C CD1   . TYR B 2 399 ? 134.359 136.108 113.690 1.00 24.63  ? 320 TYR A CD1   1 
ATOM   3626 C CD2   . TYR B 2 399 ? 135.710 136.108 115.649 1.00 24.63  ? 320 TYR A CD2   1 
ATOM   3627 C CE1   . TYR B 2 399 ? 133.324 135.534 114.398 1.00 24.63  ? 320 TYR A CE1   1 
ATOM   3628 C CE2   . TYR B 2 399 ? 134.679 135.532 116.365 1.00 24.63  ? 320 TYR A CE2   1 
ATOM   3629 C CZ    . TYR B 2 399 ? 133.488 135.247 115.733 1.00 24.63  ? 320 TYR A CZ    1 
ATOM   3630 O OH    . TYR B 2 399 ? 132.455 134.674 116.436 1.00 24.63  ? 320 TYR A OH    1 
ATOM   3631 N N     . THR B 2 400 ? 138.338 140.044 112.753 1.00 37.02  ? 321 THR A N     1 
ATOM   3632 C CA    . THR B 2 400 ? 139.352 140.694 111.936 1.00 37.02  ? 321 THR A CA    1 
ATOM   3633 C C     . THR B 2 400 ? 140.751 140.236 112.332 1.00 37.02  ? 321 THR A C     1 
ATOM   3634 O O     . THR B 2 400 ? 141.019 139.921 113.493 1.00 37.02  ? 321 THR A O     1 
ATOM   3635 C CB    . THR B 2 400 ? 139.254 142.214 112.063 1.00 37.02  ? 321 THR A CB    1 
ATOM   3636 O OG1   . THR B 2 400 ? 140.137 142.831 111.119 1.00 37.02  ? 321 THR A OG1   1 
ATOM   3637 C CG2   . THR B 2 400 ? 139.630 142.660 113.468 1.00 37.02  ? 321 THR A CG2   1 
ATOM   3638 N N     . HIS B 2 401 ? 141.645 140.203 111.343 1.00 41.63  ? 322 HIS A N     1 
ATOM   3639 C CA    . HIS B 2 401 ? 143.016 139.746 111.534 1.00 41.63  ? 322 HIS A CA    1 
ATOM   3640 C C     . HIS B 2 401 ? 144.000 140.760 110.967 1.00 41.63  ? 322 HIS A C     1 
ATOM   3641 O O     . HIS B 2 401 ? 143.775 141.322 109.890 1.00 41.63  ? 322 HIS A O     1 
ATOM   3642 C CB    . HIS B 2 401 ? 143.233 138.392 110.864 1.00 41.63  ? 322 HIS A CB    1 
ATOM   3643 C CG    . HIS B 2 401 ? 144.407 137.633 111.396 1.00 41.63  ? 322 HIS A CG    1 
ATOM   3644 N ND1   . HIS B 2 401 ? 145.697 138.113 111.329 1.00 41.63  ? 322 HIS A ND1   1 
ATOM   3645 C CD2   . HIS B 2 401 ? 144.487 136.421 111.992 1.00 41.63  ? 322 HIS A CD2   1 
ATOM   3646 C CE1   . HIS B 2 401 ? 146.520 137.231 111.865 1.00 41.63  ? 322 HIS A CE1   1 
ATOM   3647 N NE2   . HIS B 2 401 ? 145.812 136.196 112.277 1.00 41.63  ? 322 HIS A NE2   1 
ATOM   3648 N N     . PHE B 2 402 ? 145.095 140.985 111.697 1.00 52.93  ? 323 PHE A N     1 
ATOM   3649 C CA    . PHE B 2 402 ? 146.123 141.938 111.286 1.00 52.93  ? 323 PHE A CA    1 
ATOM   3650 C C     . PHE B 2 402 ? 147.526 141.340 111.307 1.00 52.93  ? 323 PHE A C     1 
ATOM   3651 O O     . PHE B 2 402 ? 148.365 141.700 110.475 1.00 52.93  ? 323 PHE A O     1 
ATOM   3652 C CB    . PHE B 2 402 ? 146.091 143.175 112.185 1.00 52.93  ? 323 PHE A CB    1 
ATOM   3653 C CG    . PHE B 2 402 ? 145.170 144.252 111.699 1.00 52.93  ? 323 PHE A CG    1 
ATOM   3654 C CD1   . PHE B 2 402 ? 143.824 144.002 111.501 1.00 52.93  ? 323 PHE A CD1   1 
ATOM   3655 C CD2   . PHE B 2 402 ? 145.655 145.520 111.439 1.00 52.93  ? 323 PHE A CD2   1 
ATOM   3656 C CE1   . PHE B 2 402 ? 142.983 144.997 111.052 1.00 52.93  ? 323 PHE A CE1   1 
ATOM   3657 C CE2   . PHE B 2 402 ? 144.820 146.515 110.992 1.00 52.93  ? 323 PHE A CE2   1 
ATOM   3658 C CZ    . PHE B 2 402 ? 143.484 146.256 110.798 1.00 52.93  ? 323 PHE A CZ    1 
ATOM   3659 N N     . THR B 2 403 ? 147.794 140.440 112.252 1.00 56.60  ? 324 THR A N     1 
ATOM   3660 C CA    . THR B 2 403 ? 149.154 139.971 112.499 1.00 56.60  ? 324 THR A CA    1 
ATOM   3661 C C     . THR B 2 403 ? 149.787 139.427 111.224 1.00 56.60  ? 324 THR A C     1 
ATOM   3662 O O     . THR B 2 403 ? 149.116 138.806 110.396 1.00 56.60  ? 324 THR A O     1 
ATOM   3663 C CB    . THR B 2 403 ? 149.151 138.896 113.589 1.00 56.60  ? 324 THR A CB    1 
ATOM   3664 O OG1   . THR B 2 403 ? 148.682 139.461 114.820 1.00 56.60  ? 324 THR A OG1   1 
ATOM   3665 C CG2   . THR B 2 403 ? 150.551 138.334 113.796 1.00 56.60  ? 324 THR A CG2   1 
ATOM   3666 N N     . CYS B 2 404 ? 151.089 139.678 111.076 1.00 62.02  ? 325 CYS A N     1 
ATOM   3667 C CA    . CYS B 2 404 ? 151.809 139.370 109.846 1.00 62.02  ? 325 CYS A CA    1 
ATOM   3668 C C     . CYS B 2 404 ? 151.550 137.941 109.388 1.00 62.02  ? 325 CYS A C     1 
ATOM   3669 O O     . CYS B 2 404 ? 151.333 137.039 110.201 1.00 62.02  ? 325 CYS A O     1 
ATOM   3670 C CB    . CYS B 2 404 ? 153.311 139.585 110.054 1.00 62.02  ? 325 CYS A CB    1 
ATOM   3671 S SG    . CYS B 2 404 ? 154.306 139.341 108.565 1.00 62.02  ? 325 CYS A SG    1 
ATOM   3672 N N     . ALA B 2 405 ? 151.570 137.749 108.066 1.00 57.84  ? 326 ALA A N     1 
ATOM   3673 C CA    . ALA B 2 405 ? 151.373 136.418 107.505 1.00 57.84  ? 326 ALA A CA    1 
ATOM   3674 C C     . ALA B 2 405 ? 152.568 135.513 107.770 1.00 57.84  ? 326 ALA A C     1 
ATOM   3675 O O     . ALA B 2 405 ? 152.417 134.287 107.823 1.00 57.84  ? 326 ALA A O     1 
ATOM   3676 C CB    . ALA B 2 405 ? 151.112 136.516 106.002 1.00 57.84  ? 326 ALA A CB    1 
ATOM   3677 N N     . THR B 2 406 ? 153.761 136.091 107.934 1.00 60.20  ? 327 THR A N     1 
ATOM   3678 C CA    . THR B 2 406 ? 154.947 135.273 108.165 1.00 60.20  ? 327 THR A CA    1 
ATOM   3679 C C     . THR B 2 406 ? 154.805 134.450 109.439 1.00 60.20  ? 327 THR A C     1 
ATOM   3680 O O     . THR B 2 406 ? 155.151 133.263 109.462 1.00 60.20  ? 327 THR A O     1 
ATOM   3681 C CB    . THR B 2 406 ? 156.192 136.157 108.239 1.00 60.20  ? 327 THR A CB    1 
ATOM   3682 O OG1   . THR B 2 406 ? 156.017 137.153 109.254 1.00 60.20  ? 327 THR A OG1   1 
ATOM   3683 C CG2   . THR B 2 406 ? 156.448 136.837 106.900 1.00 60.20  ? 327 THR A CG2   1 
ATOM   3684 N N     . ASP B 2 407 ? 154.299 135.060 110.506 1.00 57.02  ? 328 ASP A N     1 
ATOM   3685 C CA    . ASP B 2 407 ? 154.049 134.323 111.735 1.00 57.02  ? 328 ASP A CA    1 
ATOM   3686 C C     . ASP B 2 407 ? 152.930 133.312 111.518 1.00 57.02  ? 328 ASP A C     1 
ATOM   3687 O O     . ASP B 2 407 ? 151.942 133.591 110.833 1.00 57.02  ? 328 ASP A O     1 
ATOM   3688 C CB    . ASP B 2 407 ? 153.684 135.284 112.866 1.00 57.02  ? 328 ASP A CB    1 
ATOM   3689 C CG    . ASP B 2 407 ? 153.735 134.625 114.231 1.00 57.02  ? 328 ASP A CG    1 
ATOM   3690 O OD1   . ASP B 2 407 ? 154.064 133.422 114.301 1.00 57.02  ? 328 ASP A OD1   1 
ATOM   3691 O OD2   . ASP B 2 407 ? 153.450 135.311 115.234 1.00 57.02  ? 328 ASP A OD2   1 
ATOM   3692 N N     . THR B 2 408 ? 153.088 132.131 112.108 1.00 54.17  ? 329 THR A N     1 
ATOM   3693 C CA    . THR B 2 408 ? 152.129 131.040 111.933 1.00 54.17  ? 329 THR A CA    1 
ATOM   3694 C C     . THR B 2 408 ? 150.930 131.192 112.866 1.00 54.17  ? 329 THR A C     1 
ATOM   3695 O O     . THR B 2 408 ? 150.630 130.317 113.677 1.00 54.17  ? 329 THR A O     1 
ATOM   3696 C CB    . THR B 2 408 ? 152.823 129.701 112.153 1.00 54.17  ? 329 THR A CB    1 
ATOM   3697 O OG1   . THR B 2 408 ? 153.415 129.672 113.458 1.00 54.17  ? 329 THR A OG1   1 
ATOM   3698 C CG2   . THR B 2 408 ? 153.903 129.480 111.103 1.00 54.17  ? 329 THR A CG2   1 
ATOM   3699 N N     . LYS B 2 409 ? 150.234 132.322 112.749 1.00 48.44  ? 330 LYS A N     1 
ATOM   3700 C CA    . LYS B 2 409 ? 149.038 132.599 113.533 1.00 48.44  ? 330 LYS A CA    1 
ATOM   3701 C C     . LYS B 2 409 ? 147.773 132.641 112.688 1.00 48.44  ? 330 LYS A C     1 
ATOM   3702 O O     . LYS B 2 409 ? 146.675 132.715 113.248 1.00 48.44  ? 330 LYS A O     1 
ATOM   3703 C CB    . LYS B 2 409 ? 149.190 133.930 114.277 1.00 48.44  ? 330 LYS A CB    1 
ATOM   3704 C CG    . LYS B 2 409 ? 150.416 134.023 115.171 1.00 48.44  ? 330 LYS A CG    1 
ATOM   3705 C CD    . LYS B 2 409 ? 150.063 133.739 116.626 1.00 48.44  ? 330 LYS A CD    1 
ATOM   3706 C CE    . LYS B 2 409 ? 151.225 134.026 117.568 1.00 48.44  ? 330 LYS A CE    1 
ATOM   3707 N NZ    . LYS B 2 409 ? 151.902 135.322 117.283 1.00 48.44  ? 330 LYS A NZ    1 
ATOM   3708 N N     . ASN B 2 410 ? 147.895 132.601 111.360 1.00 41.48  ? 331 ASN A N     1 
ATOM   3709 C CA    . ASN B 2 410 ? 146.718 132.735 110.506 1.00 41.48  ? 331 ASN A CA    1 
ATOM   3710 C C     . ASN B 2 410 ? 145.738 131.593 110.736 1.00 41.48  ? 331 ASN A C     1 
ATOM   3711 O O     . ASN B 2 410 ? 144.527 131.814 110.845 1.00 41.48  ? 331 ASN A O     1 
ATOM   3712 C CB    . ASN B 2 410 ? 147.140 132.794 109.038 1.00 41.48  ? 331 ASN A CB    1 
ATOM   3713 C CG    . ASN B 2 410 ? 148.224 133.821 108.784 1.00 41.48  ? 331 ASN A CG    1 
ATOM   3714 O OD1   . ASN B 2 410 ? 149.364 133.473 108.479 1.00 41.48  ? 331 ASN A OD1   1 
ATOM   3715 N ND2   . ASN B 2 410 ? 147.874 135.095 108.909 1.00 41.48  ? 331 ASN A ND2   1 
ATOM   3716 N N     . VAL B 2 411 ? 146.242 130.360 110.805 1.00 34.08  ? 332 VAL A N     1 
ATOM   3717 C CA    . VAL B 2 411 ? 145.364 129.216 111.030 1.00 34.08  ? 332 VAL A CA    1 
ATOM   3718 C C     . VAL B 2 411 ? 144.832 129.226 112.457 1.00 34.08  ? 332 VAL A C     1 
ATOM   3719 O O     . VAL B 2 411 ? 143.666 128.896 112.702 1.00 34.08  ? 332 VAL A O     1 
ATOM   3720 C CB    . VAL B 2 411 ? 146.098 127.902 110.711 1.00 34.08  ? 332 VAL A CB    1 
ATOM   3721 C CG1   . VAL B 2 411 ? 145.116 126.743 110.687 1.00 34.08  ? 332 VAL A CG1   1 
ATOM   3722 C CG2   . VAL B 2 411 ? 146.828 128.007 109.381 1.00 34.08  ? 332 VAL A CG2   1 
ATOM   3723 N N     . GLN B 2 412 ? 145.676 129.603 113.420 1.00 33.23  ? 333 GLN A N     1 
ATOM   3724 C CA    . GLN B 2 412 ? 145.249 129.609 114.815 1.00 33.23  ? 333 GLN A CA    1 
ATOM   3725 C C     . GLN B 2 412 ? 144.063 130.541 115.023 1.00 33.23  ? 333 GLN A C     1 
ATOM   3726 O O     . GLN B 2 412 ? 143.116 130.201 115.742 1.00 33.23  ? 333 GLN A O     1 
ATOM   3727 C CB    . GLN B 2 412 ? 146.417 130.013 115.715 1.00 33.23  ? 333 GLN A CB    1 
ATOM   3728 C CG    . GLN B 2 412 ? 146.088 130.018 117.200 1.00 33.23  ? 333 GLN A CG    1 
ATOM   3729 C CD    . GLN B 2 412 ? 145.683 128.651 117.709 1.00 33.23  ? 333 GLN A CD    1 
ATOM   3730 O OE1   . GLN B 2 412 ? 144.500 128.375 117.908 1.00 33.23  ? 333 GLN A OE1   1 
ATOM   3731 N NE2   . GLN B 2 412 ? 146.666 127.784 117.924 1.00 33.23  ? 333 GLN A NE2   1 
ATOM   3732 N N     . PHE B 2 413 ? 144.097 131.723 114.406 1.00 31.10  ? 334 PHE A N     1 
ATOM   3733 C CA    . PHE B 2 413 ? 142.970 132.643 114.517 1.00 31.10  ? 334 PHE A CA    1 
ATOM   3734 C C     . PHE B 2 413 ? 141.719 132.046 113.887 1.00 31.10  ? 334 PHE A C     1 
ATOM   3735 O O     . PHE B 2 413 ? 140.610 132.210 114.407 1.00 31.10  ? 334 PHE A O     1 
ATOM   3736 C CB    . PHE B 2 413 ? 143.323 133.981 113.867 1.00 31.10  ? 334 PHE A CB    1 
ATOM   3737 C CG    . PHE B 2 413 ? 142.252 135.026 114.007 1.00 31.10  ? 334 PHE A CG    1 
ATOM   3738 C CD1   . PHE B 2 413 ? 141.172 135.057 113.140 1.00 31.10  ? 334 PHE A CD1   1 
ATOM   3739 C CD2   . PHE B 2 413 ? 142.327 135.980 115.006 1.00 31.10  ? 334 PHE A CD2   1 
ATOM   3740 C CE1   . PHE B 2 413 ? 140.190 136.018 113.269 1.00 31.10  ? 334 PHE A CE1   1 
ATOM   3741 C CE2   . PHE B 2 413 ? 141.348 136.942 115.139 1.00 31.10  ? 334 PHE A CE2   1 
ATOM   3742 C CZ    . PHE B 2 413 ? 140.279 136.961 114.269 1.00 31.10  ? 334 PHE A CZ    1 
ATOM   3743 N N     . VAL B 2 414 ? 141.877 131.353 112.759 1.00 28.34  ? 335 VAL A N     1 
ATOM   3744 C CA    . VAL B 2 414 ? 140.738 130.679 112.143 1.00 28.34  ? 335 VAL A CA    1 
ATOM   3745 C C     . VAL B 2 414 ? 140.184 129.620 113.085 1.00 28.34  ? 335 VAL A C     1 
ATOM   3746 O O     . VAL B 2 414 ? 138.965 129.450 113.203 1.00 28.34  ? 335 VAL A O     1 
ATOM   3747 C CB    . VAL B 2 414 ? 141.144 130.071 110.787 1.00 28.34  ? 335 VAL A CB    1 
ATOM   3748 C CG1   . VAL B 2 414 ? 139.984 129.294 110.186 1.00 28.34  ? 335 VAL A CG1   1 
ATOM   3749 C CG2   . VAL B 2 414 ? 141.604 131.156 109.833 1.00 28.34  ? 335 VAL A CG2   1 
ATOM   3750 N N     . PHE B 2 415 ? 141.069 128.890 113.767 1.00 27.91  ? 336 PHE A N     1 
ATOM   3751 C CA    . PHE B 2 415 ? 140.624 127.859 114.698 1.00 27.91  ? 336 PHE A CA    1 
ATOM   3752 C C     . PHE B 2 415 ? 139.820 128.462 115.844 1.00 27.91  ? 336 PHE A C     1 
ATOM   3753 O O     . PHE B 2 415 ? 138.794 127.910 116.256 1.00 27.91  ? 336 PHE A O     1 
ATOM   3754 C CB    . PHE B 2 415 ? 141.831 127.087 115.232 1.00 27.91  ? 336 PHE A CB    1 
ATOM   3755 C CG    . PHE B 2 415 ? 141.498 126.134 116.342 1.00 27.91  ? 336 PHE A CG    1 
ATOM   3756 C CD1   . PHE B 2 415 ? 140.874 124.929 116.073 1.00 27.91  ? 336 PHE A CD1   1 
ATOM   3757 C CD2   . PHE B 2 415 ? 141.808 126.444 117.654 1.00 27.91  ? 336 PHE A CD2   1 
ATOM   3758 C CE1   . PHE B 2 415 ? 140.565 124.052 117.092 1.00 27.91  ? 336 PHE A CE1   1 
ATOM   3759 C CE2   . PHE B 2 415 ? 141.502 125.570 118.677 1.00 27.91  ? 336 PHE A CE2   1 
ATOM   3760 C CZ    . PHE B 2 415 ? 140.880 124.372 118.395 1.00 27.91  ? 336 PHE A CZ    1 
ATOM   3761 N N     . ASP B 2 416 ? 140.281 129.592 116.384 1.00 27.32  ? 337 ASP A N     1 
ATOM   3762 C CA    . ASP B 2 416 ? 139.547 130.242 117.466 1.00 27.32  ? 337 ASP A CA    1 
ATOM   3763 C C     . ASP B 2 416 ? 138.197 130.756 116.986 1.00 27.32  ? 337 ASP A C     1 
ATOM   3764 O O     . ASP B 2 416 ? 137.181 130.596 117.674 1.00 27.32  ? 337 ASP A O     1 
ATOM   3765 C CB    . ASP B 2 416 ? 140.377 131.386 118.045 1.00 27.32  ? 337 ASP A CB    1 
ATOM   3766 C CG    . ASP B 2 416 ? 141.765 130.947 118.458 1.00 27.32  ? 337 ASP A CG    1 
ATOM   3767 O OD1   . ASP B 2 416 ? 142.032 129.727 118.443 1.00 27.32  ? 337 ASP A OD1   1 
ATOM   3768 O OD2   . ASP B 2 416 ? 142.590 131.821 118.798 1.00 27.32  ? 337 ASP A OD2   1 
ATOM   3769 N N     . ALA B 2 417 ? 138.166 131.381 115.807 1.00 23.51  ? 338 ALA A N     1 
ATOM   3770 C CA    . ALA B 2 417 ? 136.919 131.943 115.302 1.00 23.51  ? 338 ALA A CA    1 
ATOM   3771 C C     . ALA B 2 417 ? 135.881 130.857 115.058 1.00 23.51  ? 338 ALA A C     1 
ATOM   3772 O O     . ALA B 2 417 ? 134.705 131.028 115.396 1.00 23.51  ? 338 ALA A O     1 
ATOM   3773 C CB    . ALA B 2 417 ? 137.183 132.729 114.019 1.00 23.51  ? 338 ALA A CB    1 
ATOM   3774 N N     . VAL B 2 418 ? 136.294 129.731 114.476 1.00 23.39  ? 339 VAL A N     1 
ATOM   3775 C CA    . VAL B 2 418 ? 135.347 128.648 114.238 1.00 23.39  ? 339 VAL A CA    1 
ATOM   3776 C C     . VAL B 2 418 ? 134.888 128.036 115.553 1.00 23.39  ? 339 VAL A C     1 
ATOM   3777 O O     . VAL B 2 418 ? 133.722 127.653 115.685 1.00 23.39  ? 339 VAL A O     1 
ATOM   3778 C CB    . VAL B 2 418 ? 135.957 127.583 113.312 1.00 23.39  ? 339 VAL A CB    1 
ATOM   3779 C CG1   . VAL B 2 418 ? 136.272 128.181 111.949 1.00 23.39  ? 339 VAL A CG1   1 
ATOM   3780 C CG2   . VAL B 2 418 ? 137.199 126.969 113.943 1.00 23.39  ? 339 VAL A CG2   1 
ATOM   3781 N N     . THR B 2 419 ? 135.780 127.922 116.538 1.00 24.95  ? 340 THR A N     1 
ATOM   3782 C CA    . THR B 2 419 ? 135.373 127.417 117.845 1.00 24.95  ? 340 THR A CA    1 
ATOM   3783 C C     . THR B 2 419 ? 134.309 128.315 118.463 1.00 24.95  ? 340 THR A C     1 
ATOM   3784 O O     . THR B 2 419 ? 133.295 127.834 118.982 1.00 24.95  ? 340 THR A O     1 
ATOM   3785 C CB    . THR B 2 419 ? 136.588 127.313 118.768 1.00 24.95  ? 340 THR A CB    1 
ATOM   3786 O OG1   . THR B 2 419 ? 137.562 126.438 118.186 1.00 24.95  ? 340 THR A OG1   1 
ATOM   3787 C CG2   . THR B 2 419 ? 136.181 126.778 120.130 1.00 24.95  ? 340 THR A CG2   1 
ATOM   3788 N N     . ASP B 2 420 ? 134.523 129.631 118.404 1.00 25.09  ? 341 ASP A N     1 
ATOM   3789 C CA    . ASP B 2 420 ? 133.539 130.570 118.930 1.00 25.09  ? 341 ASP A CA    1 
ATOM   3790 C C     . ASP B 2 420 ? 132.217 130.458 118.180 1.00 25.09  ? 341 ASP A C     1 
ATOM   3791 O O     . ASP B 2 420 ? 131.138 130.456 118.788 1.00 25.09  ? 341 ASP A O     1 
ATOM   3792 C CB    . ASP B 2 420 ? 134.090 131.993 118.842 1.00 25.09  ? 341 ASP A CB    1 
ATOM   3793 C CG    . ASP B 2 420 ? 133.200 133.005 119.524 1.00 25.09  ? 341 ASP A CG    1 
ATOM   3794 O OD1   . ASP B 2 420 ? 132.987 132.885 120.748 1.00 25.09  ? 341 ASP A OD1   1 
ATOM   3795 O OD2   . ASP B 2 420 ? 132.706 133.923 118.836 1.00 25.09  ? 341 ASP A OD2   1 
ATOM   3796 N N     . VAL B 2 421 ? 132.283 130.365 116.850 1.00 22.17  ? 342 VAL A N     1 
ATOM   3797 C CA    . VAL B 2 421 ? 131.066 130.265 116.051 1.00 22.17  ? 342 VAL A CA    1 
ATOM   3798 C C     . VAL B 2 421 ? 130.292 129.008 116.421 1.00 22.17  ? 342 VAL A C     1 
ATOM   3799 O O     . VAL B 2 421 ? 129.070 129.044 116.594 1.00 22.17  ? 342 VAL A O     1 
ATOM   3800 C CB    . VAL B 2 421 ? 131.410 130.292 114.550 1.00 22.17  ? 342 VAL A CB    1 
ATOM   3801 C CG1   . VAL B 2 421 ? 130.182 129.958 113.716 1.00 22.17  ? 342 VAL A CG1   1 
ATOM   3802 C CG2   . VAL B 2 421 ? 131.968 131.647 114.156 1.00 22.17  ? 342 VAL A CG2   1 
ATOM   3803 N N     . ILE B 2 422 ? 130.990 127.879 116.550 1.00 24.03  ? 343 ILE A N     1 
ATOM   3804 C CA    . ILE B 2 422 ? 130.323 126.619 116.857 1.00 24.03  ? 343 ILE A CA    1 
ATOM   3805 C C     . ILE B 2 422 ? 129.720 126.665 118.254 1.00 24.03  ? 343 ILE A C     1 
ATOM   3806 O O     . ILE B 2 422 ? 128.612 126.169 118.485 1.00 24.03  ? 343 ILE A O     1 
ATOM   3807 C CB    . ILE B 2 422 ? 131.304 125.442 116.706 1.00 24.03  ? 343 ILE A CB    1 
ATOM   3808 C CG1   . ILE B 2 422 ? 131.695 125.245 115.237 1.00 24.03  ? 343 ILE A CG1   1 
ATOM   3809 C CG2   . ILE B 2 422 ? 130.696 124.168 117.274 1.00 24.03  ? 343 ILE A CG2   1 
ATOM   3810 C CD1   . ILE B 2 422 ? 130.545 124.866 114.321 1.00 24.03  ? 343 ILE A CD1   1 
ATOM   3811 N N     . ILE B 2 423 ? 130.444 127.249 119.212 1.00 25.82  ? 344 ILE A N     1 
ATOM   3812 C CA    . ILE B 2 423 ? 129.924 127.346 120.574 1.00 25.82  ? 344 ILE A CA    1 
ATOM   3813 C C     . ILE B 2 423 ? 128.649 128.179 120.593 1.00 25.82  ? 344 ILE A C     1 
ATOM   3814 O O     . ILE B 2 423 ? 127.652 127.811 121.226 1.00 25.82  ? 344 ILE A O     1 
ATOM   3815 C CB    . ILE B 2 423 ? 130.994 127.925 121.516 1.00 25.82  ? 344 ILE A CB    1 
ATOM   3816 C CG1   . ILE B 2 423 ? 132.103 126.895 121.743 1.00 25.82  ? 344 ILE A CG1   1 
ATOM   3817 C CG2   . ILE B 2 423 ? 130.370 128.336 122.839 1.00 25.82  ? 344 ILE A CG2   1 
ATOM   3818 C CD1   . ILE B 2 423 ? 133.370 127.476 122.324 1.00 25.82  ? 344 ILE A CD1   1 
ATOM   3819 N N     . LYS B 2 424 ? 128.660 129.320 119.898 1.00 25.93  ? 345 LYS A N     1 
ATOM   3820 C CA    . LYS B 2 424 ? 127.465 130.158 119.873 1.00 25.93  ? 345 LYS A CA    1 
ATOM   3821 C C     . LYS B 2 424 ? 126.322 129.481 119.127 1.00 25.93  ? 345 LYS A C     1 
ATOM   3822 O O     . LYS B 2 424 ? 125.155 129.659 119.488 1.00 25.93  ? 345 LYS A O     1 
ATOM   3823 C CB    . LYS B 2 424 ? 127.776 131.523 119.261 1.00 25.93  ? 345 LYS A CB    1 
ATOM   3824 C CG    . LYS B 2 424 ? 128.622 132.417 120.154 1.00 25.93  ? 345 LYS A CG    1 
ATOM   3825 C CD    . LYS B 2 424 ? 128.439 133.883 119.782 1.00 25.93  ? 345 LYS A CD    1 
ATOM   3826 C CE    . LYS B 2 424 ? 129.383 134.795 120.551 1.00 25.93  ? 345 LYS A CE    1 
ATOM   3827 N NZ    . LYS B 2 424 ? 130.811 134.425 120.392 1.00 25.93  ? 345 LYS A NZ    1 
ATOM   3828 N N     . ASN B 2 425 ? 126.626 128.709 118.083 1.00 25.28  ? 346 ASN A N     1 
ATOM   3829 C CA    . ASN B 2 425 ? 125.574 127.968 117.393 1.00 25.28  ? 346 ASN A CA    1 
ATOM   3830 C C     . ASN B 2 425 ? 124.948 126.933 118.318 1.00 25.28  ? 346 ASN A C     1 
ATOM   3831 O O     . ASN B 2 425 ? 123.724 126.766 118.348 1.00 25.28  ? 346 ASN A O     1 
ATOM   3832 C CB    . ASN B 2 425 ? 126.134 127.297 116.139 1.00 25.28  ? 346 ASN A CB    1 
ATOM   3833 C CG    . ASN B 2 425 ? 126.691 128.291 115.141 1.00 25.28  ? 346 ASN A CG    1 
ATOM   3834 O OD1   . ASN B 2 425 ? 127.791 128.113 114.622 1.00 25.28  ? 346 ASN A OD1   1 
ATOM   3835 N ND2   . ASN B 2 425 ? 125.930 129.344 114.865 1.00 25.28  ? 346 ASN A ND2   1 
ATOM   3836 N N     . ASN B 2 426 ? 125.781 126.222 119.080 1.00 26.85  ? 347 ASN A N     1 
ATOM   3837 C CA    . ASN B 2 426 ? 125.266 125.251 120.038 1.00 26.85  ? 347 ASN A CA    1 
ATOM   3838 C C     . ASN B 2 426 ? 124.376 125.929 121.070 1.00 26.85  ? 347 ASN A C     1 
ATOM   3839 O O     . ASN B 2 426 ? 123.261 125.472 121.348 1.00 26.85  ? 347 ASN A O     1 
ATOM   3840 C CB    . ASN B 2 426 ? 126.428 124.530 120.725 1.00 26.85  ? 347 ASN A CB    1 
ATOM   3841 C CG    . ASN B 2 426 ? 126.904 123.318 119.951 1.00 26.85  ? 347 ASN A CG    1 
ATOM   3842 O OD1   . ASN B 2 426 ? 126.183 122.775 119.115 1.00 26.85  ? 347 ASN A OD1   1 
ATOM   3843 N ND2   . ASN B 2 426 ? 128.129 122.886 120.228 1.00 26.85  ? 347 ASN A ND2   1 
ATOM   3844 N N     . LEU B 2 427 ? 124.854 127.035 121.644 1.00 28.87  ? 348 LEU A N     1 
ATOM   3845 C CA    . LEU B 2 427 ? 124.073 127.738 122.656 1.00 28.87  ? 348 LEU A CA    1 
ATOM   3846 C C     . LEU B 2 427 ? 122.755 128.245 122.084 1.00 28.87  ? 348 LEU A C     1 
ATOM   3847 O O     . LEU B 2 427 ? 121.707 128.140 122.731 1.00 28.87  ? 348 LEU A O     1 
ATOM   3848 C CB    . LEU B 2 427 ? 124.887 128.894 123.234 1.00 28.87  ? 348 LEU A CB    1 
ATOM   3849 C CG    . LEU B 2 427 ? 125.736 128.568 124.465 1.00 28.87  ? 348 LEU A CG    1 
ATOM   3850 C CD1   . LEU B 2 427 ? 126.504 127.269 124.281 1.00 28.87  ? 348 LEU A CD1   1 
ATOM   3851 C CD2   . LEU B 2 427 ? 126.688 129.713 124.761 1.00 28.87  ? 348 LEU A CD2   1 
ATOM   3852 N N     . LYS B 2 428 ? 122.815 128.828 120.891 1.00 31.96  ? 349 LYS A N     1 
ATOM   3853 C CA    . LYS B 2 428 ? 121.598 129.405 120.266 1.00 31.96  ? 349 LYS A CA    1 
ATOM   3854 C C     . LYS B 2 428 ? 120.657 128.266 119.872 1.00 31.96  ? 349 LYS A C     1 
ATOM   3855 O O     . LYS B 2 428 ? 119.572 128.550 119.334 1.00 31.96  ? 349 LYS A O     1 
ATOM   3856 C CB    . LYS B 2 428 ? 122.001 130.253 119.057 1.00 31.96  ? 349 LYS A CB    1 
ATOM   3857 C CG    . LYS B 2 428 ? 120.924 131.169 118.493 1.00 31.96  ? 349 LYS A CG    1 
ATOM   3858 C CD    . LYS B 2 428 ? 121.455 132.121 117.445 1.00 31.96  ? 349 LYS A CD    1 
ATOM   3859 C CE    . LYS B 2 428 ? 122.250 131.425 116.361 1.00 31.96  ? 349 LYS A CE    1 
ATOM   3860 N NZ    . LYS B 2 428 ? 122.782 132.388 115.369 1.00 31.96  ? 349 LYS A NZ    1 
ATOM   3861 N N     . ASP B 2 429 ? 121.053 127.023 120.148 1.00 35.05  ? 350 ASP A N     1 
ATOM   3862 C CA    . ASP B 2 429 ? 120.235 125.861 119.710 1.00 35.05  ? 350 ASP A CA    1 
ATOM   3863 C C     . ASP B 2 429 ? 119.442 125.327 120.905 1.00 35.05  ? 350 ASP A C     1 
ATOM   3864 O O     . ASP B 2 429 ? 118.290 124.905 120.700 1.00 35.05  ? 350 ASP A O     1 
ATOM   3865 C CB    . ASP B 2 429 ? 121.125 124.796 119.063 1.00 35.05  ? 350 ASP A CB    1 
ATOM   3866 C CG    . ASP B 2 429 ? 120.357 123.706 118.338 1.00 35.05  ? 350 ASP A CG    1 
ATOM   3867 O OD1   . ASP B 2 429 ? 119.575 124.048 117.427 1.00 35.05  ? 350 ASP A OD1   1 
ATOM   3868 O OD2   . ASP B 2 429 ? 120.562 122.524 118.677 1.00 35.05  ? 350 ASP A OD2   1 
ATOM   3869 N N     . CYS B 2 430 ? 120.042 125.355 122.099 1.00 32.81  ? 351 CYS A N     1 
ATOM   3870 C CA    . CYS B 2 430 ? 119.363 124.865 123.327 1.00 32.81  ? 351 CYS A CA    1 
ATOM   3871 C C     . CYS B 2 430 ? 118.575 126.013 123.966 1.00 32.81  ? 351 CYS A C     1 
ATOM   3872 O O     . CYS B 2 430 ? 118.053 125.818 125.076 1.00 32.81  ? 351 CYS A O     1 
ATOM   3873 C CB    . CYS B 2 430 ? 120.379 124.299 124.311 1.00 32.81  ? 351 CYS A CB    1 
ATOM   3874 S SG    . CYS B 2 430 ? 121.763 125.410 124.668 1.00 32.81  ? 351 CYS A SG    1 
ATOM   3875 N N     . GLY B 2 431 ? 118.498 127.161 123.292 1.00 35.24  ? 352 GLY A N     1 
ATOM   3876 C CA    . GLY B 2 431 ? 117.723 128.305 123.804 1.00 35.24  ? 352 GLY A CA    1 
ATOM   3877 C C     . GLY B 2 431 ? 118.517 129.135 124.792 1.00 35.24  ? 352 GLY A C     1 
ATOM   3878 O O     . GLY B 2 431 ? 117.992 130.165 125.251 1.00 35.24  ? 352 GLY A O     1 
ATOM   3879 N N     . LEU B 2 432 ? 119.748 128.720 125.093 1.00 31.33  ? 353 LEU A N     1 
ATOM   3880 C CA    . LEU B 2 432 ? 120.604 129.464 126.053 1.00 31.33  ? 353 LEU A CA    1 
ATOM   3881 C C     . LEU B 2 432 ? 121.173 130.705 125.362 1.00 31.33  ? 353 LEU A C     1 
ATOM   3882 O O     . LEU B 2 432 ? 122.300 131.103 125.718 1.00 31.33  ? 353 LEU A O     1 
ATOM   3883 C CB    . LEU B 2 432 ? 121.732 128.554 126.545 1.00 31.33  ? 353 LEU A CB    1 
ATOM   3884 C CG    . LEU B 2 432 ? 121.326 127.519 127.590 1.00 31.33  ? 353 LEU A CG    1 
ATOM   3885 C CD1   . LEU B 2 432 ? 122.534 127.071 128.397 1.00 31.33  ? 353 LEU A CD1   1 
ATOM   3886 C CD2   . LEU B 2 432 ? 120.250 128.081 128.503 1.00 31.33  ? 353 LEU A CD2   1 
ATOM   3887 N N     . PHE B 2 433 ? 120.429 131.284 124.413 1.00 35.35  ? 354 PHE A N     1 
ATOM   3888 C CA    . PHE B 2 433 ? 120.876 132.535 123.749 1.00 35.35  ? 354 PHE A CA    1 
ATOM   3889 C C     . PHE B 2 433 ? 119.822 133.625 123.971 1.00 35.35  ? 354 PHE A C     1 
ATOM   3890 O O     . PHE B 2 433 ? 119.908 134.666 123.323 1.00 35.35  ? 354 PHE A O     1 
ATOM   3891 C CB    . PHE B 2 433 ? 121.133 132.301 122.262 1.00 35.35  ? 354 PHE A CB    1 
ATOM   3892 C CG    . PHE B 2 433 ? 122.411 132.919 121.754 1.00 35.35  ? 354 PHE A CG    1 
ATOM   3893 C CD1   . PHE B 2 433 ? 123.630 132.588 122.323 1.00 35.35  ? 354 PHE A CD1   1 
ATOM   3894 C CD2   . PHE B 2 433 ? 122.397 133.829 120.710 1.00 35.35  ? 354 PHE A CD2   1 
ATOM   3895 C CE1   . PHE B 2 433 ? 124.806 133.156 121.860 1.00 35.35  ? 354 PHE A CE1   1 
ATOM   3896 C CE2   . PHE B 2 433 ? 123.575 134.394 120.246 1.00 35.35  ? 354 PHE A CE2   1 
ATOM   3897 C CZ    . PHE B 2 433 ? 124.777 134.057 120.823 1.00 35.35  ? 354 PHE A CZ    1 
ATOM   3898 O OXT   . PHE B 2 433 ? 118.928 133.404 124.802 1.00 35.35  ? 354 PHE A OXT   1 
ATOM   3899 N N     . ASP C 3 10  ? 126.426 154.576 60.263  1.00 108.84 ? 5   ASP B N     1 
ATOM   3900 C CA    . ASP C 3 10  ? 126.826 153.184 60.620  1.00 108.84 ? 5   ASP B CA    1 
ATOM   3901 C C     . ASP C 3 10  ? 126.167 152.181 59.681  1.00 108.84 ? 5   ASP B C     1 
ATOM   3902 O O     . ASP C 3 10  ? 125.083 152.435 59.155  1.00 108.84 ? 5   ASP B O     1 
ATOM   3903 C CB    . ASP C 3 10  ? 126.447 152.870 62.067  1.00 108.84 ? 5   ASP B CB    1 
ATOM   3904 C CG    . ASP C 3 10  ? 124.962 153.035 62.328  1.00 108.84 ? 5   ASP B CG    1 
ATOM   3905 O OD1   . ASP C 3 10  ? 124.316 153.827 61.610  1.00 108.84 ? 5   ASP B OD1   1 
ATOM   3906 O OD2   . ASP C 3 10  ? 124.441 152.371 63.248  1.00 108.84 ? 5   ASP B OD2   1 
ATOM   3907 N N     . GLN C 3 11  ? 126.828 151.042 59.472  1.00 108.88 ? 6   GLN B N     1 
ATOM   3908 C CA    . GLN C 3 11  ? 126.292 149.983 58.623  1.00 108.88 ? 6   GLN B CA    1 
ATOM   3909 C C     . GLN C 3 11  ? 126.111 148.677 59.385  1.00 108.88 ? 6   GLN B C     1 
ATOM   3910 O O     . GLN C 3 11  ? 125.047 148.059 59.283  1.00 108.88 ? 6   GLN B O     1 
ATOM   3911 C CB    . GLN C 3 11  ? 127.194 149.791 57.394  1.00 108.88 ? 6   GLN B CB    1 
ATOM   3912 C CG    . GLN C 3 11  ? 128.630 149.375 57.692  1.00 108.88 ? 6   GLN B CG    1 
ATOM   3913 C CD    . GLN C 3 11  ? 128.818 147.871 57.731  1.00 108.88 ? 6   GLN B CD    1 
ATOM   3914 O OE1   . GLN C 3 11  ? 128.107 147.125 57.057  1.00 108.88 ? 6   GLN B OE1   1 
ATOM   3915 N NE2   . GLN C 3 11  ? 129.792 147.419 58.512  1.00 108.88 ? 6   GLN B NE2   1 
ATOM   3916 N N     . LEU C 3 12  ? 127.111 148.234 60.151  1.00 108.95 ? 7   LEU B N     1 
ATOM   3917 C CA    . LEU C 3 12  ? 126.960 146.990 60.901  1.00 108.95 ? 7   LEU B CA    1 
ATOM   3918 C C     . LEU C 3 12  ? 126.002 147.168 62.075  1.00 108.95 ? 7   LEU B C     1 
ATOM   3919 O O     . LEU C 3 12  ? 125.105 146.343 62.284  1.00 108.95 ? 7   LEU B O     1 
ATOM   3920 C CB    . LEU C 3 12  ? 128.335 146.481 61.350  1.00 108.95 ? 7   LEU B CB    1 
ATOM   3921 C CG    . LEU C 3 12  ? 129.249 147.288 62.278  1.00 108.95 ? 7   LEU B CG    1 
ATOM   3922 C CD1   . LEU C 3 12  ? 128.914 147.109 63.754  1.00 108.95 ? 7   LEU B CD1   1 
ATOM   3923 C CD2   . LEU C 3 12  ? 130.693 146.896 62.007  1.00 108.95 ? 7   LEU B CD2   1 
ATOM   3924 N N     . ARG C 3 13  ? 126.154 148.253 62.840  1.00 108.85 ? 8   ARG B N     1 
ATOM   3925 C CA    . ARG C 3 13  ? 125.198 148.517 63.911  1.00 108.85 ? 8   ARG B CA    1 
ATOM   3926 C C     . ARG C 3 13  ? 123.817 148.807 63.342  1.00 108.85 ? 8   ARG B C     1 
ATOM   3927 O O     . ARG C 3 13  ? 122.807 148.301 63.846  1.00 108.85 ? 8   ARG B O     1 
ATOM   3928 C CB    . ARG C 3 13  ? 125.668 149.686 64.780  1.00 108.85 ? 8   ARG B CB    1 
ATOM   3929 C CG    . ARG C 3 13  ? 127.062 149.528 65.361  1.00 108.85 ? 8   ARG B CG    1 
ATOM   3930 C CD    . ARG C 3 13  ? 127.114 148.394 66.381  1.00 108.85 ? 8   ARG B CD    1 
ATOM   3931 N NE    . ARG C 3 13  ? 128.476 148.067 66.785  1.00 108.85 ? 8   ARG B NE    1 
ATOM   3932 C CZ    . ARG C 3 13  ? 129.262 148.865 67.495  1.00 108.85 ? 8   ARG B CZ    1 
ATOM   3933 N NH1   . ARG C 3 13  ? 128.844 150.046 67.923  1.00 108.85 ? 8   ARG B NH1   1 
ATOM   3934 N NH2   . ARG C 3 13  ? 130.495 148.466 67.790  1.00 108.85 ? 8   ARG B NH2   1 
ATOM   3935 N N     . GLN C 3 14  ? 123.756 149.621 62.287  1.00 106.38 ? 9   GLN B N     1 
ATOM   3936 C CA    . GLN C 3 14  ? 122.478 149.915 61.651  1.00 106.38 ? 9   GLN B CA    1 
ATOM   3937 C C     . GLN C 3 14  ? 121.853 148.649 61.081  1.00 106.38 ? 9   GLN B C     1 
ATOM   3938 O O     . GLN C 3 14  ? 120.642 148.436 61.205  1.00 106.38 ? 9   GLN B O     1 
ATOM   3939 C CB    . GLN C 3 14  ? 122.674 150.969 60.558  1.00 106.38 ? 9   GLN B CB    1 
ATOM   3940 C CG    . GLN C 3 14  ? 121.631 150.951 59.450  1.00 106.38 ? 9   GLN B CG    1 
ATOM   3941 C CD    . GLN C 3 14  ? 120.219 151.113 59.976  1.00 106.38 ? 9   GLN B CD    1 
ATOM   3942 O OE1   . GLN C 3 14  ? 120.012 151.568 61.101  1.00 106.38 ? 9   GLN B OE1   1 
ATOM   3943 N NE2   . GLN C 3 14  ? 119.239 150.738 59.164  1.00 106.38 ? 9   GLN B NE2   1 
ATOM   3944 N N     . GLU C 3 15  ? 122.664 147.798 60.448  1.00 102.26 ? 10  GLU B N     1 
ATOM   3945 C CA    . GLU C 3 15  ? 122.140 146.553 59.896  1.00 102.26 ? 10  GLU B CA    1 
ATOM   3946 C C     . GLU C 3 15  ? 121.575 145.665 60.997  1.00 102.26 ? 10  GLU B C     1 
ATOM   3947 O O     . GLU C 3 15  ? 120.473 145.123 60.868  1.00 102.26 ? 10  GLU B O     1 
ATOM   3948 C CB    . GLU C 3 15  ? 123.237 145.820 59.123  1.00 102.26 ? 10  GLU B CB    1 
ATOM   3949 C CG    . GLU C 3 15  ? 122.821 144.447 58.611  1.00 102.26 ? 10  GLU B CG    1 
ATOM   3950 C CD    . GLU C 3 15  ? 123.621 144.000 57.400  1.00 102.26 ? 10  GLU B CD    1 
ATOM   3951 O OE1   . GLU C 3 15  ? 124.451 144.790 56.903  1.00 102.26 ? 10  GLU B OE1   1 
ATOM   3952 O OE2   . GLU C 3 15  ? 123.419 142.855 56.945  1.00 102.26 ? 10  GLU B OE2   1 
ATOM   3953 N N     . ALA C 3 16  ? 122.312 145.517 62.100  1.00 101.70 ? 11  ALA B N     1 
ATOM   3954 C CA    . ALA C 3 16  ? 121.828 144.687 63.199  1.00 101.70 ? 11  ALA B CA    1 
ATOM   3955 C C     . ALA C 3 16  ? 120.523 145.236 63.762  1.00 101.70 ? 11  ALA B C     1 
ATOM   3956 O O     . ALA C 3 16  ? 119.555 144.491 63.974  1.00 101.70 ? 11  ALA B O     1 
ATOM   3957 C CB    . ALA C 3 16  ? 122.888 144.604 64.296  1.00 101.70 ? 11  ALA B CB    1 
ATOM   3958 N N     . GLU C 3 17  ? 120.479 146.547 64.011  1.00 99.86  ? 12  GLU B N     1 
ATOM   3959 C CA    . GLU C 3 17  ? 119.293 147.149 64.606  1.00 99.86  ? 12  GLU B CA    1 
ATOM   3960 C C     . GLU C 3 17  ? 118.088 147.003 63.686  1.00 99.86  ? 12  GLU B C     1 
ATOM   3961 O O     . GLU C 3 17  ? 117.013 146.570 64.118  1.00 99.86  ? 12  GLU B O     1 
ATOM   3962 C CB    . GLU C 3 17  ? 119.561 148.622 64.920  1.00 99.86  ? 12  GLU B CB    1 
ATOM   3963 C CG    . GLU C 3 17  ? 118.479 149.294 65.751  1.00 99.86  ? 12  GLU B CG    1 
ATOM   3964 C CD    . GLU C 3 17  ? 118.432 148.778 67.177  1.00 99.86  ? 12  GLU B CD    1 
ATOM   3965 O OE1   . GLU C 3 17  ? 119.274 147.927 67.532  1.00 99.86  ? 12  GLU B OE1   1 
ATOM   3966 O OE2   . GLU C 3 17  ? 117.552 149.223 67.943  1.00 99.86  ? 12  GLU B OE2   1 
ATOM   3967 N N     . GLN C 3 18  ? 118.251 147.355 62.408  1.00 99.18  ? 13  GLN B N     1 
ATOM   3968 C CA    . GLN C 3 18  ? 117.130 147.280 61.479  1.00 99.18  ? 13  GLN B CA    1 
ATOM   3969 C C     . GLN C 3 18  ? 116.670 145.841 61.293  1.00 99.18  ? 13  GLN B C     1 
ATOM   3970 O O     . GLN C 3 18  ? 115.465 145.574 61.240  1.00 99.18  ? 13  GLN B O     1 
ATOM   3971 C CB    . GLN C 3 18  ? 117.506 147.918 60.139  1.00 99.18  ? 13  GLN B CB    1 
ATOM   3972 C CG    . GLN C 3 18  ? 118.534 147.153 59.318  1.00 99.18  ? 13  GLN B CG    1 
ATOM   3973 C CD    . GLN C 3 18  ? 117.914 146.088 58.431  1.00 99.18  ? 13  GLN B CD    1 
ATOM   3974 O OE1   . GLN C 3 18  ? 116.694 146.024 58.276  1.00 99.18  ? 13  GLN B OE1   1 
ATOM   3975 N NE2   . GLN C 3 18  ? 118.755 145.248 57.841  1.00 99.18  ? 13  GLN B NE2   1 
ATOM   3976 N N     . LEU C 3 19  ? 117.608 144.895 61.206  1.00 94.33  ? 14  LEU B N     1 
ATOM   3977 C CA    . LEU C 3 19  ? 117.230 143.493 61.119  1.00 94.33  ? 14  LEU B CA    1 
ATOM   3978 C C     . LEU C 3 19  ? 116.363 143.146 62.317  1.00 94.33  ? 14  LEU B C     1 
ATOM   3979 O O     . LEU C 3 19  ? 115.150 142.968 62.173  1.00 94.33  ? 14  LEU B O     1 
ATOM   3980 C CB    . LEU C 3 19  ? 118.469 142.595 61.072  1.00 94.33  ? 14  LEU B CB    1 
ATOM   3981 C CG    . LEU C 3 19  ? 119.129 142.375 59.709  1.00 94.33  ? 14  LEU B CG    1 
ATOM   3982 C CD1   . LEU C 3 19  ? 120.372 141.512 59.859  1.00 94.33  ? 14  LEU B CD1   1 
ATOM   3983 C CD2   . LEU C 3 19  ? 118.159 141.744 58.721  1.00 94.33  ? 14  LEU B CD2   1 
ATOM   3984 N N     . LYS C 3 20  ? 116.948 143.175 63.517  1.00 88.78  ? 15  LYS B N     1 
ATOM   3985 C CA    . LYS C 3 20  ? 116.206 142.750 64.699  1.00 88.78  ? 15  LYS B CA    1 
ATOM   3986 C C     . LYS C 3 20  ? 114.835 143.414 64.747  1.00 88.78  ? 15  LYS B C     1 
ATOM   3987 O O     . LYS C 3 20  ? 113.815 142.747 64.964  1.00 88.78  ? 15  LYS B O     1 
ATOM   3988 C CB    . LYS C 3 20  ? 117.003 143.071 65.966  1.00 88.78  ? 15  LYS B CB    1 
ATOM   3989 C CG    . LYS C 3 20  ? 118.079 142.047 66.341  1.00 88.78  ? 15  LYS B CG    1 
ATOM   3990 C CD    . LYS C 3 20  ? 117.578 140.600 66.343  1.00 88.78  ? 15  LYS B CD    1 
ATOM   3991 C CE    . LYS C 3 20  ? 116.279 140.430 67.122  1.00 88.78  ? 15  LYS B CE    1 
ATOM   3992 N NZ    . LYS C 3 20  ? 115.789 139.024 67.079  1.00 88.78  ? 15  LYS B NZ    1 
ATOM   3993 N N     . ASN C 3 21  ? 114.787 144.727 64.505  1.00 91.01  ? 16  ASN B N     1 
ATOM   3994 C CA    . ASN C 3 21  ? 113.523 145.446 64.595  1.00 91.01  ? 16  ASN B CA    1 
ATOM   3995 C C     . ASN C 3 21  ? 112.509 144.918 63.588  1.00 91.01  ? 16  ASN B C     1 
ATOM   3996 O O     . ASN C 3 21  ? 111.347 144.688 63.933  1.00 91.01  ? 16  ASN B O     1 
ATOM   3997 C CB    . ASN C 3 21  ? 113.756 146.943 64.389  1.00 91.01  ? 16  ASN B CB    1 
ATOM   3998 C CG    . ASN C 3 21  ? 114.364 147.610 65.606  1.00 91.01  ? 16  ASN B CG    1 
ATOM   3999 O OD1   . ASN C 3 21  ? 115.463 148.158 65.544  1.00 91.01  ? 16  ASN B OD1   1 
ATOM   4000 N ND2   . ASN C 3 21  ? 113.648 147.564 66.724  1.00 91.01  ? 16  ASN B ND2   1 
ATOM   4001 N N     . GLN C 3 22  ? 112.928 144.705 62.336  1.00 88.82  ? 17  GLN B N     1 
ATOM   4002 C CA    . GLN C 3 22  ? 111.960 144.325 61.311  1.00 88.82  ? 17  GLN B CA    1 
ATOM   4003 C C     . GLN C 3 22  ? 111.517 142.874 61.470  1.00 88.82  ? 17  GLN B C     1 
ATOM   4004 O O     . GLN C 3 22  ? 110.332 142.564 61.295  1.00 88.82  ? 17  GLN B O     1 
ATOM   4005 C CB    . GLN C 3 22  ? 112.534 144.582 59.915  1.00 88.82  ? 17  GLN B CB    1 
ATOM   4006 C CG    . GLN C 3 22  ? 113.503 143.534 59.405  1.00 88.82  ? 17  GLN B CG    1 
ATOM   4007 C CD    . GLN C 3 22  ? 112.821 142.425 58.620  1.00 88.82  ? 17  GLN B CD    1 
ATOM   4008 O OE1   . GLN C 3 22  ? 111.628 142.497 58.326  1.00 88.82  ? 17  GLN B OE1   1 
ATOM   4009 N NE2   . GLN C 3 22  ? 113.582 141.393 58.274  1.00 88.82  ? 17  GLN B NE2   1 
ATOM   4010 N N     . ILE C 3 23  ? 112.437 141.969 61.817  1.00 84.62  ? 18  ILE B N     1 
ATOM   4011 C CA    . ILE C 3 23  ? 112.025 140.593 62.097  1.00 84.62  ? 18  ILE B CA    1 
ATOM   4012 C C     . ILE C 3 23  ? 111.039 140.558 63.258  1.00 84.62  ? 18  ILE B C     1 
ATOM   4013 O O     . ILE C 3 23  ? 110.003 139.886 63.190  1.00 84.62  ? 18  ILE B O     1 
ATOM   4014 C CB    . ILE C 3 23  ? 113.238 139.678 62.359  1.00 84.62  ? 18  ILE B CB    1 
ATOM   4015 C CG1   . ILE C 3 23  ? 114.099 139.509 61.100  1.00 84.62  ? 18  ILE B CG1   1 
ATOM   4016 C CG2   . ILE C 3 23  ? 112.775 138.314 62.862  1.00 84.62  ? 18  ILE B CG2   1 
ATOM   4017 C CD1   . ILE C 3 23  ? 115.196 140.504 60.929  1.00 84.62  ? 18  ILE B CD1   1 
ATOM   4018 N N     . ARG C 3 24  ? 111.338 141.278 64.344  1.00 78.59  ? 19  ARG B N     1 
ATOM   4019 C CA    . ARG C 3 24  ? 110.438 141.246 65.493  1.00 78.59  ? 19  ARG B CA    1 
ATOM   4020 C C     . ARG C 3 24  ? 109.096 141.894 65.167  1.00 78.59  ? 19  ARG B C     1 
ATOM   4021 O O     . ARG C 3 24  ? 108.047 141.414 65.612  1.00 78.59  ? 19  ARG B O     1 
ATOM   4022 C CB    . ARG C 3 24  ? 111.097 141.923 66.694  1.00 78.59  ? 19  ARG B CB    1 
ATOM   4023 C CG    . ARG C 3 24  ? 112.229 141.102 67.291  1.00 78.59  ? 19  ARG B CG    1 
ATOM   4024 C CD    . ARG C 3 24  ? 112.635 141.601 68.667  1.00 78.59  ? 19  ARG B CD    1 
ATOM   4025 N NE    . ARG C 3 24  ? 113.732 140.817 69.223  1.00 78.59  ? 19  ARG B NE    1 
ATOM   4026 C CZ    . ARG C 3 24  ? 113.618 139.567 69.652  1.00 78.59  ? 19  ARG B CZ    1 
ATOM   4027 N NH1   . ARG C 3 24  ? 112.461 138.924 69.615  1.00 78.59  ? 19  ARG B NH1   1 
ATOM   4028 N NH2   . ARG C 3 24  ? 114.691 138.945 70.131  1.00 78.59  ? 19  ARG B NH2   1 
ATOM   4029 N N     . ASP C 3 25  ? 109.105 142.979 64.389  1.00 79.69  ? 20  ASP B N     1 
ATOM   4030 C CA    . ASP C 3 25  ? 107.854 143.624 64.008  1.00 79.69  ? 20  ASP B CA    1 
ATOM   4031 C C     . ASP C 3 25  ? 107.005 142.705 63.140  1.00 79.69  ? 20  ASP B C     1 
ATOM   4032 O O     . ASP C 3 25  ? 105.787 142.621 63.327  1.00 79.69  ? 20  ASP B O     1 
ATOM   4033 C CB    . ASP C 3 25  ? 108.145 144.935 63.277  1.00 79.69  ? 20  ASP B CB    1 
ATOM   4034 C CG    . ASP C 3 25  ? 106.886 145.618 62.777  1.00 79.69  ? 20  ASP B CG    1 
ATOM   4035 O OD1   . ASP C 3 25  ? 105.787 145.286 63.270  1.00 79.69  ? 20  ASP B OD1   1 
ATOM   4036 O OD2   . ASP C 3 25  ? 106.995 146.489 61.889  1.00 79.69  ? 20  ASP B OD2   1 
ATOM   4037 N N     . ALA C 3 26  ? 107.626 142.012 62.183  1.00 75.16  ? 21  ALA B N     1 
ATOM   4038 C CA    . ALA C 3 26  ? 106.882 141.063 61.362  1.00 75.16  ? 21  ALA B CA    1 
ATOM   4039 C C     . ALA C 3 26  ? 106.335 139.921 62.208  1.00 75.16  ? 21  ALA B C     1 
ATOM   4040 O O     . ALA C 3 26  ? 105.192 139.486 62.016  1.00 75.16  ? 21  ALA B O     1 
ATOM   4041 C CB    . ALA C 3 26  ? 107.775 140.528 60.244  1.00 75.16  ? 21  ALA B CB    1 
ATOM   4042 N N     . ARG C 3 27  ? 107.137 139.424 63.152  1.00 69.18  ? 22  ARG B N     1 
ATOM   4043 C CA    . ARG C 3 27  ? 106.675 138.360 64.037  1.00 69.18  ? 22  ARG B CA    1 
ATOM   4044 C C     . ARG C 3 27  ? 105.458 138.810 64.835  1.00 69.18  ? 22  ARG B C     1 
ATOM   4045 O O     . ARG C 3 27  ? 104.475 138.071 64.965  1.00 69.18  ? 22  ARG B O     1 
ATOM   4046 C CB    . ARG C 3 27  ? 107.810 137.940 64.972  1.00 69.18  ? 22  ARG B CB    1 
ATOM   4047 C CG    . ARG C 3 27  ? 107.545 136.664 65.755  1.00 69.18  ? 22  ARG B CG    1 
ATOM   4048 C CD    . ARG C 3 27  ? 108.509 136.514 66.923  1.00 69.18  ? 22  ARG B CD    1 
ATOM   4049 N NE    . ARG C 3 27  ? 109.889 136.800 66.553  1.00 69.18  ? 22  ARG B NE    1 
ATOM   4050 C CZ    . ARG C 3 27  ? 110.916 136.736 67.390  1.00 69.18  ? 22  ARG B CZ    1 
ATOM   4051 N NH1   . ARG C 3 27  ? 110.756 136.392 68.657  1.00 69.18  ? 22  ARG B NH1   1 
ATOM   4052 N NH2   . ARG C 3 27  ? 112.136 137.025 66.944  1.00 69.18  ? 22  ARG B NH2   1 
ATOM   4053 N N     . LYS C 3 28  ? 105.509 140.027 65.380  1.00 71.26  ? 23  LYS B N     1 
ATOM   4054 C CA    . LYS C 3 28  ? 104.378 140.546 66.143  1.00 71.26  ? 23  LYS B CA    1 
ATOM   4055 C C     . LYS C 3 28  ? 103.155 140.735 65.253  1.00 71.26  ? 23  LYS B C     1 
ATOM   4056 O O     . LYS C 3 28  ? 102.033 140.396 65.645  1.00 71.26  ? 23  LYS B O     1 
ATOM   4057 C CB    . LYS C 3 28  ? 104.767 141.864 66.814  1.00 71.26  ? 23  LYS B CB    1 
ATOM   4058 C CG    . LYS C 3 28  ? 103.603 142.634 67.435  1.00 71.26  ? 23  LYS B CG    1 
ATOM   4059 C CD    . LYS C 3 28  ? 102.827 141.795 68.444  1.00 71.26  ? 23  LYS B CD    1 
ATOM   4060 C CE    . LYS C 3 28  ? 103.732 141.227 69.527  1.00 71.26  ? 23  LYS B CE    1 
ATOM   4061 N NZ    . LYS C 3 28  ? 102.957 140.659 70.664  1.00 71.26  ? 23  LYS B NZ    1 
ATOM   4062 N N     . ALA C 3 29  ? 103.353 141.278 64.049  1.00 73.70  ? 24  ALA B N     1 
ATOM   4063 C CA    . ALA C 3 29  ? 102.226 141.549 63.163  1.00 73.70  ? 24  ALA B CA    1 
ATOM   4064 C C     . ALA C 3 29  ? 101.536 140.261 62.735  1.00 73.70  ? 24  ALA B C     1 
ATOM   4065 O O     . ALA C 3 29  ? 100.302 140.187 62.716  1.00 73.70  ? 24  ALA B O     1 
ATOM   4066 C CB    . ALA C 3 29  ? 102.701 142.333 61.939  1.00 73.70  ? 24  ALA B CB    1 
ATOM   4067 N N     . CYS C 3 30  ? 102.312 139.235 62.389  1.00 67.75  ? 25  CYS B N     1 
ATOM   4068 C CA    . CYS C 3 30  ? 101.739 137.964 61.971  1.00 67.75  ? 25  CYS B CA    1 
ATOM   4069 C C     . CYS C 3 30  ? 101.292 137.102 63.143  1.00 67.75  ? 25  CYS B C     1 
ATOM   4070 O O     . CYS C 3 30  ? 100.663 136.062 62.920  1.00 67.75  ? 25  CYS B O     1 
ATOM   4071 C CB    . CYS C 3 30  ? 102.743 137.186 61.114  1.00 67.75  ? 25  CYS B CB    1 
ATOM   4072 S SG    . CYS C 3 30  ? 103.283 138.080 59.639  1.00 67.75  ? 25  CYS B SG    1 
ATOM   4073 N N     . ALA C 3 31  ? 101.599 137.500 64.376  1.00 63.52  ? 26  ALA B N     1 
ATOM   4074 C CA    . ALA C 3 31  ? 101.053 136.812 65.536  1.00 63.52  ? 26  ALA B CA    1 
ATOM   4075 C C     . ALA C 3 31  ? 99.536  136.936 65.541  1.00 63.52  ? 26  ALA B C     1 
ATOM   4076 O O     . ALA C 3 31  ? 98.989  138.032 65.395  1.00 63.52  ? 26  ALA B O     1 
ATOM   4077 C CB    . ALA C 3 31  ? 101.640 137.397 66.822  1.00 63.52  ? 26  ALA B CB    1 
ATOM   4078 N N     . ASP C 3 32  ? 98.857  135.803 65.712  1.00 59.20  ? 27  ASP B N     1 
ATOM   4079 C CA    . ASP C 3 32  ? 97.401  135.765 65.618  1.00 59.20  ? 27  ASP B CA    1 
ATOM   4080 C C     . ASP C 3 32  ? 96.743  135.909 66.987  1.00 59.20  ? 27  ASP B C     1 
ATOM   4081 O O     . ASP C 3 32  ? 95.949  136.829 67.207  1.00 59.20  ? 27  ASP B O     1 
ATOM   4082 C CB    . ASP C 3 32  ? 96.962  134.463 64.941  1.00 59.20  ? 27  ASP B CB    1 
ATOM   4083 C CG    . ASP C 3 32  ? 97.461  134.351 63.515  1.00 59.20  ? 27  ASP B CG    1 
ATOM   4084 O OD1   . ASP C 3 32  ? 97.746  135.400 62.900  1.00 59.20  ? 27  ASP B OD1   1 
ATOM   4085 O OD2   . ASP C 3 32  ? 97.571  133.214 63.011  1.00 59.20  ? 27  ASP B OD2   1 
ATOM   4086 N N     . ALA C 3 33  ? 97.062  135.009 67.914  1.00 57.27  ? 28  ALA B N     1 
ATOM   4087 C CA    . ALA C 3 33  ? 96.459  135.043 69.237  1.00 57.27  ? 28  ALA B CA    1 
ATOM   4088 C C     . ALA C 3 33  ? 97.350  134.285 70.209  1.00 57.27  ? 28  ALA B C     1 
ATOM   4089 O O     . ALA C 3 33  ? 98.217  133.505 69.807  1.00 57.27  ? 28  ALA B O     1 
ATOM   4090 C CB    . ALA C 3 33  ? 95.048  134.448 69.224  1.00 57.27  ? 28  ALA B CB    1 
ATOM   4091 N N     . THR C 3 34  ? 97.122  134.529 71.496  1.00 52.12  ? 29  THR B N     1 
ATOM   4092 C CA    . THR C 3 34  ? 97.890  133.876 72.543  1.00 52.12  ? 29  THR B CA    1 
ATOM   4093 C C     . THR C 3 34  ? 97.343  132.476 72.815  1.00 52.12  ? 29  THR B C     1 
ATOM   4094 O O     . THR C 3 34  ? 96.324  132.053 72.263  1.00 52.12  ? 29  THR B O     1 
ATOM   4095 C CB    . THR C 3 34  ? 97.866  134.710 73.824  1.00 52.12  ? 29  THR B CB    1 
ATOM   4096 O OG1   . THR C 3 34  ? 96.510  135.023 74.170  1.00 52.12  ? 29  THR B OG1   1 
ATOM   4097 C CG2   . THR C 3 34  ? 98.653  136.000 73.638  1.00 52.12  ? 29  THR B CG2   1 
ATOM   4098 N N     . LEU C 3 35  ? 98.045  131.749 73.688  1.00 43.40  ? 30  LEU B N     1 
ATOM   4099 C CA    . LEU C 3 35  ? 97.625  130.394 74.030  1.00 43.40  ? 30  LEU B CA    1 
ATOM   4100 C C     . LEU C 3 35  ? 96.248  130.390 74.683  1.00 43.40  ? 30  LEU B C     1 
ATOM   4101 O O     . LEU C 3 35  ? 95.406  129.541 74.368  1.00 43.40  ? 30  LEU B O     1 
ATOM   4102 C CB    . LEU C 3 35  ? 98.661  129.751 74.954  1.00 43.40  ? 30  LEU B CB    1 
ATOM   4103 C CG    . LEU C 3 35  ? 98.499  128.264 75.283  1.00 43.40  ? 30  LEU B CG    1 
ATOM   4104 C CD1   . LEU C 3 35  ? 98.206  127.442 74.040  1.00 43.40  ? 30  LEU B CD1   1 
ATOM   4105 C CD2   . LEU C 3 35  ? 99.748  127.745 75.980  1.00 43.40  ? 30  LEU B CD2   1 
ATOM   4106 N N     . SER C 3 36  ? 96.000  131.334 75.594  1.00 49.14  ? 31  SER B N     1 
ATOM   4107 C CA    . SER C 3 36  ? 94.721  131.369 76.295  1.00 49.14  ? 31  SER B CA    1 
ATOM   4108 C C     . SER C 3 36  ? 93.564  131.684 75.355  1.00 49.14  ? 31  SER B C     1 
ATOM   4109 O O     . SER C 3 36  ? 92.447  131.199 75.566  1.00 49.14  ? 31  SER B O     1 
ATOM   4110 C CB    . SER C 3 36  ? 94.774  132.397 77.425  1.00 49.14  ? 31  SER B CB    1 
ATOM   4111 O OG    . SER C 3 36  ? 94.929  133.708 76.914  1.00 49.14  ? 31  SER B OG    1 
ATOM   4112 N N     . GLN C 3 37  ? 93.807  132.492 74.321  1.00 54.70  ? 32  GLN B N     1 
ATOM   4113 C CA    . GLN C 3 37  ? 92.717  132.937 73.458  1.00 54.70  ? 32  GLN B CA    1 
ATOM   4114 C C     . GLN C 3 37  ? 92.075  131.775 72.710  1.00 54.70  ? 32  GLN B C     1 
ATOM   4115 O O     . GLN C 3 37  ? 90.868  131.803 72.444  1.00 54.70  ? 32  GLN B O     1 
ATOM   4116 C CB    . GLN C 3 37  ? 93.235  133.983 72.470  1.00 54.70  ? 32  GLN B CB    1 
ATOM   4117 C CG    . GLN C 3 37  ? 92.171  134.573 71.553  1.00 54.70  ? 32  GLN B CG    1 
ATOM   4118 C CD    . GLN C 3 37  ? 91.137  135.391 72.302  1.00 54.70  ? 32  GLN B CD    1 
ATOM   4119 O OE1   . GLN C 3 37  ? 91.207  135.537 73.522  1.00 54.70  ? 32  GLN B OE1   1 
ATOM   4120 N NE2   . GLN C 3 37  ? 90.170  135.933 71.571  1.00 54.70  ? 32  GLN B NE2   1 
ATOM   4121 N N     . ILE C 3 38  ? 92.857  130.750 72.362  1.00 52.16  ? 33  ILE B N     1 
ATOM   4122 C CA    . ILE C 3 38  ? 92.345  129.628 71.579  1.00 52.16  ? 33  ILE B CA    1 
ATOM   4123 C C     . ILE C 3 38  ? 91.766  128.517 72.446  1.00 52.16  ? 33  ILE B C     1 
ATOM   4124 O O     . ILE C 3 38  ? 91.029  127.664 71.924  1.00 52.16  ? 33  ILE B O     1 
ATOM   4125 C CB    . ILE C 3 38  ? 93.444  129.043 70.664  1.00 52.16  ? 33  ILE B CB    1 
ATOM   4126 C CG1   . ILE C 3 38  ? 94.133  130.155 69.867  1.00 52.16  ? 33  ILE B CG1   1 
ATOM   4127 C CG2   . ILE C 3 38  ? 92.858  128.001 69.721  1.00 52.16  ? 33  ILE B CG2   1 
ATOM   4128 C CD1   . ILE C 3 38  ? 93.195  130.975 69.001  1.00 52.16  ? 33  ILE B CD1   1 
ATOM   4129 N N     . THR C 3 39  ? 92.060  128.502 73.747  1.00 45.73  ? 34  THR B N     1 
ATOM   4130 C CA    . THR C 3 39  ? 91.593  127.450 74.644  1.00 45.73  ? 34  THR B CA    1 
ATOM   4131 C C     . THR C 3 39  ? 90.602  127.974 75.678  1.00 45.73  ? 34  THR B C     1 
ATOM   4132 O O     . THR C 3 39  ? 90.391  127.331 76.711  1.00 45.73  ? 34  THR B O     1 
ATOM   4133 C CB    . THR C 3 39  ? 92.778  126.781 75.344  1.00 45.73  ? 34  THR B CB    1 
ATOM   4134 O OG1   . THR C 3 39  ? 92.329  125.612 76.042  1.00 45.73  ? 34  THR B OG1   1 
ATOM   4135 C CG2   . THR C 3 39  ? 93.431  127.737 76.330  1.00 45.73  ? 34  THR B CG2   1 
ATOM   4136 N N     . ASN C 3 40  ? 89.986  129.131 75.422  1.00 49.78  ? 35  ASN B N     1 
ATOM   4137 C CA    . ASN C 3 40  ? 89.017  129.671 76.370  1.00 49.78  ? 35  ASN B CA    1 
ATOM   4138 C C     . ASN C 3 40  ? 87.800  128.764 76.503  1.00 49.78  ? 35  ASN B C     1 
ATOM   4139 O O     . ASN C 3 40  ? 87.227  128.650 77.593  1.00 49.78  ? 35  ASN B O     1 
ATOM   4140 C CB    . ASN C 3 40  ? 88.589  131.073 75.939  1.00 49.78  ? 35  ASN B CB    1 
ATOM   4141 C CG    . ASN C 3 40  ? 87.739  131.771 76.983  1.00 49.78  ? 35  ASN B CG    1 
ATOM   4142 O OD1   . ASN C 3 40  ? 87.586  131.284 78.103  1.00 49.78  ? 35  ASN B OD1   1 
ATOM   4143 N ND2   . ASN C 3 40  ? 87.181  132.920 76.619  1.00 49.78  ? 35  ASN B ND2   1 
ATOM   4144 N N     . ASN C 3 41  ? 87.391  128.114 75.412  1.00 49.99  ? 36  ASN B N     1 
ATOM   4145 C CA    . ASN C 3 41  ? 86.236  127.225 75.461  1.00 49.99  ? 36  ASN B CA    1 
ATOM   4146 C C     . ASN C 3 41  ? 86.547  125.903 76.149  1.00 49.99  ? 36  ASN B C     1 
ATOM   4147 O O     . ASN C 3 41  ? 85.617  125.199 76.558  1.00 49.99  ? 36  ASN B O     1 
ATOM   4148 C CB    . ASN C 3 41  ? 85.718  126.957 74.047  1.00 49.99  ? 36  ASN B CB    1 
ATOM   4149 C CG    . ASN C 3 41  ? 86.786  126.388 73.133  1.00 49.99  ? 36  ASN B CG    1 
ATOM   4150 O OD1   . ASN C 3 41  ? 87.980  126.481 73.420  1.00 49.99  ? 36  ASN B OD1   1 
ATOM   4151 N ND2   . ASN C 3 41  ? 86.361  125.790 72.026  1.00 49.99  ? 36  ASN B ND2   1 
ATOM   4152 N N     . ILE C 3 42  ? 87.821  125.549 76.286  1.00 43.40  ? 37  ILE B N     1 
ATOM   4153 C CA    . ILE C 3 42  ? 88.204  124.271 76.873  1.00 43.40  ? 37  ILE B CA    1 
ATOM   4154 C C     . ILE C 3 42  ? 87.988  124.320 78.378  1.00 43.40  ? 37  ILE B C     1 
ATOM   4155 O O     . ILE C 3 42  ? 88.329  125.307 79.041  1.00 43.40  ? 37  ILE B O     1 
ATOM   4156 C CB    . ILE C 3 42  ? 89.667  123.938 76.529  1.00 43.40  ? 37  ILE B CB    1 
ATOM   4157 C CG1   . ILE C 3 42  ? 89.874  123.929 75.009  1.00 43.40  ? 37  ILE B CG1   1 
ATOM   4158 C CG2   . ILE C 3 42  ? 90.065  122.599 77.133  1.00 43.40  ? 37  ILE B CG2   1 
ATOM   4159 C CD1   . ILE C 3 42  ? 89.012  122.924 74.264  1.00 43.40  ? 37  ILE B CD1   1 
ATOM   4160 N N     . ASP C 3 43  ? 87.413  123.251 78.923  1.00 40.56  ? 38  ASP B N     1 
ATOM   4161 C CA    . ASP C 3 43  ? 87.162  123.192 80.353  1.00 40.56  ? 38  ASP B CA    1 
ATOM   4162 C C     . ASP C 3 43  ? 88.474  123.004 81.116  1.00 40.56  ? 38  ASP B C     1 
ATOM   4163 O O     . ASP C 3 43  ? 89.455  122.498 80.566  1.00 40.56  ? 38  ASP B O     1 
ATOM   4164 C CB    . ASP C 3 43  ? 86.205  122.050 80.686  1.00 40.56  ? 38  ASP B CB    1 
ATOM   4165 C CG    . ASP C 3 43  ? 86.618  120.736 80.051  1.00 40.56  ? 38  ASP B CG    1 
ATOM   4166 O OD1   . ASP C 3 43  ? 87.510  120.753 79.177  1.00 40.56  ? 38  ASP B OD1   1 
ATOM   4167 O OD2   . ASP C 3 43  ? 86.053  119.688 80.427  1.00 40.56  ? 38  ASP B OD2   1 
ATOM   4168 N N     . PRO C 3 44  ? 88.518  123.407 82.390  1.00 34.09  ? 39  PRO B N     1 
ATOM   4169 C CA    . PRO C 3 44  ? 89.751  123.251 83.171  1.00 34.09  ? 39  PRO B CA    1 
ATOM   4170 C C     . PRO C 3 44  ? 89.980  121.826 83.648  1.00 34.09  ? 39  PRO B C     1 
ATOM   4171 O O     . PRO C 3 44  ? 89.204  120.921 83.325  1.00 34.09  ? 39  PRO B O     1 
ATOM   4172 C CB    . PRO C 3 44  ? 89.510  124.210 84.340  1.00 34.09  ? 39  PRO B CB    1 
ATOM   4173 C CG    . PRO C 3 44  ? 88.051  124.012 84.581  1.00 34.09  ? 39  PRO B CG    1 
ATOM   4174 C CD    . PRO C 3 44  ? 87.511  124.149 83.173  1.00 34.09  ? 39  PRO B CD    1 
ATOM   4175 N N     . VAL C 3 45  ? 91.051  121.619 84.419  1.00 25.92  ? 40  VAL B N     1 
ATOM   4176 C CA    . VAL C 3 45  ? 91.365  120.302 84.965  1.00 25.92  ? 40  VAL B CA    1 
ATOM   4177 C C     . VAL C 3 45  ? 90.807  120.098 86.365  1.00 25.92  ? 40  VAL B C     1 
ATOM   4178 O O     . VAL C 3 45  ? 90.767  118.951 86.841  1.00 25.92  ? 40  VAL B O     1 
ATOM   4179 C CB    . VAL C 3 45  ? 92.890  120.054 84.989  1.00 25.92  ? 40  VAL B CB    1 
ATOM   4180 C CG1   . VAL C 3 45  ? 93.464  120.144 83.592  1.00 25.92  ? 40  VAL B CG1   1 
ATOM   4181 C CG2   . VAL C 3 45  ? 93.587  121.034 85.924  1.00 25.92  ? 40  VAL B CG2   1 
ATOM   4182 N N     . GLY C 3 46  ? 90.371  121.159 87.037  1.00 27.44  ? 41  GLY B N     1 
ATOM   4183 C CA    . GLY C 3 46  ? 90.010  121.057 88.434  1.00 27.44  ? 41  GLY B CA    1 
ATOM   4184 C C     . GLY C 3 46  ? 91.233  121.210 89.322  1.00 27.44  ? 41  GLY B C     1 
ATOM   4185 O O     . GLY C 3 46  ? 92.288  121.697 88.904  1.00 27.44  ? 41  GLY B O     1 
ATOM   4186 N N     . ARG C 3 47  ? 91.084  120.782 90.571  1.00 21.02  ? 42  ARG B N     1 
ATOM   4187 C CA    . ARG C 3 47  ? 92.162  120.845 91.549  1.00 21.02  ? 42  ARG B CA    1 
ATOM   4188 C C     . ARG C 3 47  ? 92.941  119.537 91.510  1.00 21.02  ? 42  ARG B C     1 
ATOM   4189 O O     . ARG C 3 47  ? 92.366  118.460 91.702  1.00 21.02  ? 42  ARG B O     1 
ATOM   4190 C CB    . ARG C 3 47  ? 91.616  121.107 92.953  1.00 21.02  ? 42  ARG B CB    1 
ATOM   4191 C CG    . ARG C 3 47  ? 92.632  121.723 93.911  1.00 21.02  ? 42  ARG B CG    1 
ATOM   4192 C CD    . ARG C 3 47  ? 92.969  123.161 93.535  1.00 21.02  ? 42  ARG B CD    1 
ATOM   4193 N NE    . ARG C 3 47  ? 94.028  123.716 94.369  1.00 21.02  ? 42  ARG B NE    1 
ATOM   4194 C CZ    . ARG C 3 47  ? 94.620  124.882 94.149  1.00 21.02  ? 42  ARG B CZ    1 
ATOM   4195 N NH1   . ARG C 3 47  ? 94.287  125.645 93.121  1.00 21.02  ? 42  ARG B NH1   1 
ATOM   4196 N NH2   . ARG C 3 47  ? 95.574  125.293 94.981  1.00 21.02  ? 42  ARG B NH2   1 
ATOM   4197 N N     . ILE C 3 48  ? 94.243  119.634 91.264  1.00 17.68  ? 43  ILE B N     1 
ATOM   4198 C CA    . ILE C 3 48  ? 95.105  118.444 91.176  1.00 17.68  ? 43  ILE B CA    1 
ATOM   4199 C C     . ILE C 3 48  ? 95.567  118.155 92.596  1.00 17.68  ? 43  ILE B C     1 
ATOM   4200 O O     . ILE C 3 48  ? 96.640  118.567 93.046  1.00 17.68  ? 43  ILE B O     1 
ATOM   4201 C CB    . ILE C 3 48  ? 96.269  118.644 90.198  1.00 17.68  ? 43  ILE B CB    1 
ATOM   4202 C CG1   . ILE C 3 48  ? 95.752  118.889 88.775  1.00 17.68  ? 43  ILE B CG1   1 
ATOM   4203 C CG2   . ILE C 3 48  ? 97.202  117.441 90.220  1.00 17.68  ? 43  ILE B CG2   1 
ATOM   4204 C CD1   . ILE C 3 48  ? 94.657  117.942 88.330  1.00 17.68  ? 43  ILE B CD1   1 
ATOM   4205 N N     . GLN C 3 49  ? 94.732  117.422 93.329  1.00 17.31  ? 44  GLN B N     1 
ATOM   4206 C CA    . GLN C 3 49  ? 95.048  117.029 94.696  1.00 17.31  ? 44  GLN B CA    1 
ATOM   4207 C C     . GLN C 3 49  ? 95.885  115.758 94.650  1.00 17.31  ? 44  GLN B C     1 
ATOM   4208 O O     . GLN C 3 49  ? 95.390  114.693 94.267  1.00 17.31  ? 44  GLN B O     1 
ATOM   4209 C CB    . GLN C 3 49  ? 93.768  116.822 95.500  1.00 17.31  ? 44  GLN B CB    1 
ATOM   4210 C CG    . GLN C 3 49  ? 93.984  116.717 97.001  1.00 17.31  ? 44  GLN B CG    1 
ATOM   4211 C CD    . GLN C 3 49  ? 94.541  117.994 97.601  1.00 17.31  ? 44  GLN B CD    1 
ATOM   4212 O OE1   . GLN C 3 49  ? 95.623  117.996 98.189  1.00 17.31  ? 44  GLN B OE1   1 
ATOM   4213 N NE2   . GLN C 3 49  ? 93.805  119.089 97.450  1.00 17.31  ? 44  GLN B NE2   1 
ATOM   4214 N N     . MET C 3 50  ? 97.151  115.866 95.037  1.00 11.47  ? 45  MET B N     1 
ATOM   4215 C CA    . MET C 3 50  ? 98.089  114.758 94.975  1.00 11.47  ? 45  MET B CA    1 
ATOM   4216 C C     . MET C 3 50  ? 98.668  114.494 96.357  1.00 11.47  ? 45  MET B C     1 
ATOM   4217 O O     . MET C 3 50  ? 99.015  115.423 97.092  1.00 11.47  ? 45  MET B O     1 
ATOM   4218 C CB    . MET C 3 50  ? 99.213  115.053 93.975  1.00 11.47  ? 45  MET B CB    1 
ATOM   4219 C CG    . MET C 3 50  ? 98.796  114.870 92.523  1.00 11.47  ? 45  MET B CG    1 
ATOM   4220 S SD    . MET C 3 50  ? 99.948  115.587 91.337  1.00 11.47  ? 45  MET B SD    1 
ATOM   4221 C CE    . MET C 3 50  ? 101.510 114.991 91.967  1.00 11.47  ? 45  MET B CE    1 
ATOM   4222 N N     . ARG C 3 51  ? 98.771  113.214 96.701  1.00 11.74  ? 46  ARG B N     1 
ATOM   4223 C CA    . ARG C 3 51  ? 99.238  112.780 98.008  1.00 11.74  ? 46  ARG B CA    1 
ATOM   4224 C C     . ARG C 3 51  ? 100.645 112.212 97.895  1.00 11.74  ? 46  ARG B C     1 
ATOM   4225 O O     . ARG C 3 51  ? 101.038 111.684 96.852  1.00 11.74  ? 46  ARG B O     1 
ATOM   4226 C CB    . ARG C 3 51  ? 98.296  111.725 98.608  1.00 11.74  ? 46  ARG B CB    1 
ATOM   4227 C CG    . ARG C 3 51  ? 97.061  112.305 99.284  1.00 11.74  ? 46  ARG B CG    1 
ATOM   4228 C CD    . ARG C 3 51  ? 96.019  112.780 98.280  1.00 11.74  ? 46  ARG B CD    1 
ATOM   4229 N NE    . ARG C 3 51  ? 95.568  111.721 97.382  1.00 11.74  ? 46  ARG B NE    1 
ATOM   4230 C CZ    . ARG C 3 51  ? 94.453  111.018 97.537  1.00 11.74  ? 46  ARG B CZ    1 
ATOM   4231 N NH1   . ARG C 3 51  ? 93.651  111.206 98.573  1.00 11.74  ? 46  ARG B NH1   1 
ATOM   4232 N NH2   . ARG C 3 51  ? 94.133  110.102 96.627  1.00 11.74  ? 46  ARG B NH2   1 
ATOM   4233 N N     . THR C 3 52  ? 101.403 112.330 98.982  1.00 7.99   ? 47  THR B N     1 
ATOM   4234 C CA    . THR C 3 52  ? 102.774 111.828 99.034  1.00 7.99   ? 47  THR B CA    1 
ATOM   4235 C C     . THR C 3 52  ? 102.717 110.329 99.297  1.00 7.99   ? 47  THR B C     1 
ATOM   4236 O O     . THR C 3 52  ? 102.588 109.875 100.434 1.00 7.99   ? 47  THR B O     1 
ATOM   4237 C CB    . THR C 3 52  ? 103.574 112.552 100.109 1.00 7.99   ? 47  THR B CB    1 
ATOM   4238 O OG1   . THR C 3 52  ? 103.608 113.954 99.819  1.00 7.99   ? 47  THR B OG1   1 
ATOM   4239 C CG2   . THR C 3 52  ? 104.997 112.021 100.165 1.00 7.99   ? 47  THR B CG2   1 
ATOM   4240 N N     . ARG C 3 53  ? 102.818 109.548 98.221  1.00 10.59  ? 48  ARG B N     1 
ATOM   4241 C CA    . ARG C 3 53  ? 102.741 108.098 98.358  1.00 10.59  ? 48  ARG B CA    1 
ATOM   4242 C C     . ARG C 3 53  ? 104.004 107.536 98.996  1.00 10.59  ? 48  ARG B C     1 
ATOM   4243 O O     . ARG C 3 53  ? 103.930 106.663 99.868  1.00 10.59  ? 48  ARG B O     1 
ATOM   4244 C CB    . ARG C 3 53  ? 102.500 107.459 96.992  1.00 10.59  ? 48  ARG B CB    1 
ATOM   4245 C CG    . ARG C 3 53  ? 101.139 107.770 96.403  1.00 10.59  ? 48  ARG B CG    1 
ATOM   4246 C CD    . ARG C 3 53  ? 100.022 107.067 97.160  1.00 10.59  ? 48  ARG B CD    1 
ATOM   4247 N NE    . ARG C 3 53  ? 98.858  107.926 97.338  1.00 10.59  ? 48  ARG B NE    1 
ATOM   4248 C CZ    . ARG C 3 53  ? 97.939  108.149 96.408  1.00 10.59  ? 48  ARG B CZ    1 
ATOM   4249 N NH1   . ARG C 3 53  ? 98.013  107.588 95.212  1.00 10.59  ? 48  ARG B NH1   1 
ATOM   4250 N NH2   . ARG C 3 53  ? 96.920  108.956 96.685  1.00 10.59  ? 48  ARG B NH2   1 
ATOM   4251 N N     . ARG C 3 54  ? 105.167 108.021 98.577  1.00 8.41   ? 49  ARG B N     1 
ATOM   4252 C CA    . ARG C 3 54  ? 106.442 107.581 99.118  1.00 8.41   ? 49  ARG B CA    1 
ATOM   4253 C C     . ARG C 3 54  ? 107.276 108.798 99.487  1.00 8.41   ? 49  ARG B C     1 
ATOM   4254 O O     . ARG C 3 54  ? 107.177 109.853 98.856  1.00 8.41   ? 49  ARG B O     1 
ATOM   4255 C CB    . ARG C 3 54  ? 107.215 106.708 98.117  1.00 8.41   ? 49  ARG B CB    1 
ATOM   4256 C CG    . ARG C 3 54  ? 106.415 105.563 97.507  1.00 8.41   ? 49  ARG B CG    1 
ATOM   4257 C CD    . ARG C 3 54  ? 106.601 104.272 98.296  1.00 8.41   ? 49  ARG B CD    1 
ATOM   4258 N NE    . ARG C 3 54  ? 105.833 103.158 97.752  1.00 8.41   ? 49  ARG B NE    1 
ATOM   4259 C CZ    . ARG C 3 54  ? 104.509 103.091 97.729  1.00 8.41   ? 49  ARG B CZ    1 
ATOM   4260 N NH1   . ARG C 3 54  ? 103.756 104.055 98.233  1.00 8.41   ? 49  ARG B NH1   1 
ATOM   4261 N NH2   . ARG C 3 54  ? 103.924 102.024 97.194  1.00 8.41   ? 49  ARG B NH2   1 
ATOM   4262 N N     . THR C 3 55  ? 108.096 108.642 100.521 1.00 6.52   ? 50  THR B N     1 
ATOM   4263 C CA    . THR C 3 55  ? 109.021 109.680 100.955 1.00 6.52   ? 50  THR B CA    1 
ATOM   4264 C C     . THR C 3 55  ? 110.401 109.057 101.076 1.00 6.52   ? 50  THR B C     1 
ATOM   4265 O O     . THR C 3 55  ? 110.628 108.212 101.948 1.00 6.52   ? 50  THR B O     1 
ATOM   4266 C CB    . THR C 3 55  ? 108.585 110.296 102.288 1.00 6.52   ? 50  THR B CB    1 
ATOM   4267 O OG1   . THR C 3 55  ? 107.401 111.078 102.090 1.00 6.52   ? 50  THR B OG1   1 
ATOM   4268 C CG2   . THR C 3 55  ? 109.685 111.181 102.860 1.00 6.52   ? 50  THR B CG2   1 
ATOM   4269 N N     . LEU C 3 56  ? 111.316 109.469 100.205 1.00 6.41   ? 51  LEU B N     1 
ATOM   4270 C CA    . LEU C 3 56  ? 112.651 108.890 100.154 1.00 6.41   ? 51  LEU B CA    1 
ATOM   4271 C C     . LEU C 3 56  ? 113.543 109.582 101.175 1.00 6.41   ? 51  LEU B C     1 
ATOM   4272 O O     . LEU C 3 56  ? 113.955 110.729 100.973 1.00 6.41   ? 51  LEU B O     1 
ATOM   4273 C CB    . LEU C 3 56  ? 113.242 109.013 98.752  1.00 6.41   ? 51  LEU B CB    1 
ATOM   4274 C CG    . LEU C 3 56  ? 112.299 108.722 97.586  1.00 6.41   ? 51  LEU B CG    1 
ATOM   4275 C CD1   . LEU C 3 56  ? 113.013 108.961 96.266  1.00 6.41   ? 51  LEU B CD1   1 
ATOM   4276 C CD2   . LEU C 3 56  ? 111.766 107.301 97.668  1.00 6.41   ? 51  LEU B CD2   1 
ATOM   4277 N N     . ARG C 3 57  ? 113.841 108.882 102.263 1.00 7.18   ? 52  ARG B N     1 
ATOM   4278 C CA    . ARG C 3 57  ? 114.729 109.370 103.304 1.00 7.18   ? 52  ARG B CA    1 
ATOM   4279 C C     . ARG C 3 57  ? 116.101 108.732 103.147 1.00 7.18   ? 52  ARG B C     1 
ATOM   4280 O O     . ARG C 3 57  ? 116.221 107.574 102.738 1.00 7.18   ? 52  ARG B O     1 
ATOM   4281 C CB    . ARG C 3 57  ? 114.166 109.063 104.693 1.00 7.18   ? 52  ARG B CB    1 
ATOM   4282 C CG    . ARG C 3 57  ? 112.873 109.790 105.003 1.00 7.18   ? 52  ARG B CG    1 
ATOM   4283 C CD    . ARG C 3 57  ? 112.304 109.377 106.348 1.00 7.18   ? 52  ARG B CD    1 
ATOM   4284 N NE    . ARG C 3 57  ? 111.060 110.078 106.644 1.00 7.18   ? 52  ARG B NE    1 
ATOM   4285 C CZ    . ARG C 3 57  ? 109.847 109.622 106.358 1.00 7.18   ? 52  ARG B CZ    1 
ATOM   4286 N NH1   . ARG C 3 57  ? 109.668 108.459 105.752 1.00 7.18   ? 52  ARG B NH1   1 
ATOM   4287 N NH2   . ARG C 3 57  ? 108.786 110.354 106.684 1.00 7.18   ? 52  ARG B NH2   1 
ATOM   4288 N N     . GLY C 3 58  ? 117.134 109.497 103.480 1.00 6.78   ? 53  GLY B N     1 
ATOM   4289 C CA    . GLY C 3 58  ? 118.497 109.021 103.359 1.00 6.78   ? 53  GLY B CA    1 
ATOM   4290 C C     . GLY C 3 58  ? 119.451 110.103 102.906 1.00 6.78   ? 53  GLY B C     1 
ATOM   4291 O O     . GLY C 3 58  ? 120.646 110.049 103.210 1.00 6.78   ? 53  GLY B O     1 
ATOM   4292 N N     . HIS C 3 59  ? 118.940 111.091 102.177 1.00 6.70   ? 54  HIS B N     1 
ATOM   4293 C CA    . HIS C 3 59  ? 119.749 112.252 101.833 1.00 6.70   ? 54  HIS B CA    1 
ATOM   4294 C C     . HIS C 3 59  ? 119.888 113.151 103.054 1.00 6.70   ? 54  HIS B C     1 
ATOM   4295 O O     . HIS C 3 59  ? 118.902 113.447 103.735 1.00 6.70   ? 54  HIS B O     1 
ATOM   4296 C CB    . HIS C 3 59  ? 119.121 113.017 100.670 1.00 6.70   ? 54  HIS B CB    1 
ATOM   4297 C CG    . HIS C 3 59  ? 119.582 112.553 99.322  1.00 6.70   ? 54  HIS B CG    1 
ATOM   4298 N ND1   . HIS C 3 59  ? 120.910 112.349 99.019  1.00 6.70   ? 54  HIS B ND1   1 
ATOM   4299 C CD2   . HIS C 3 59  ? 118.891 112.266 98.194  1.00 6.70   ? 54  HIS B CD2   1 
ATOM   4300 C CE1   . HIS C 3 59  ? 121.018 111.950 97.764  1.00 6.70   ? 54  HIS B CE1   1 
ATOM   4301 N NE2   . HIS C 3 59  ? 119.807 111.892 97.242  1.00 6.70   ? 54  HIS B NE2   1 
ATOM   4302 N N     . LEU C 3 60  ? 121.118 113.578 103.338 1.00 8.48   ? 55  LEU B N     1 
ATOM   4303 C CA    . LEU C 3 60  ? 121.431 114.323 104.550 1.00 8.48   ? 55  LEU B CA    1 
ATOM   4304 C C     . LEU C 3 60  ? 121.902 115.743 104.246 1.00 8.48   ? 55  LEU B C     1 
ATOM   4305 O O     . LEU C 3 60  ? 122.714 116.305 104.982 1.00 8.48   ? 55  LEU B O     1 
ATOM   4306 C CB    . LEU C 3 60  ? 122.484 113.575 105.364 1.00 8.48   ? 55  LEU B CB    1 
ATOM   4307 C CG    . LEU C 3 60  ? 121.986 112.300 106.049 1.00 8.48   ? 55  LEU B CG    1 
ATOM   4308 C CD1   . LEU C 3 60  ? 123.152 111.501 106.595 1.00 8.48   ? 55  LEU B CD1   1 
ATOM   4309 C CD2   . LEU C 3 60  ? 120.999 112.626 107.158 1.00 8.48   ? 55  LEU B CD2   1 
ATOM   4310 N N     . ALA C 3 61  ? 121.400 116.330 103.169 1.00 8.04   ? 56  ALA B N     1 
ATOM   4311 C CA    . ALA C 3 61  ? 121.746 117.692 102.774 1.00 8.04   ? 56  ALA B CA    1 
ATOM   4312 C C     . ALA C 3 61  ? 120.753 118.119 101.699 1.00 8.04   ? 56  ALA B C     1 
ATOM   4313 O O     . ALA C 3 61  ? 119.788 117.403 101.407 1.00 8.04   ? 56  ALA B O     1 
ATOM   4314 C CB    . ALA C 3 61  ? 123.194 117.782 102.292 1.00 8.04   ? 56  ALA B CB    1 
ATOM   4315 N N     . LYS C 3 62  ? 120.983 119.289 101.111 1.00 9.97   ? 57  LYS B N     1 
ATOM   4316 C CA    . LYS C 3 62  ? 120.086 119.791 100.082 1.00 9.97   ? 57  LYS B CA    1 
ATOM   4317 C C     . LYS C 3 62  ? 120.176 118.930 98.829  1.00 9.97   ? 57  LYS B C     1 
ATOM   4318 O O     . LYS C 3 62  ? 121.266 118.559 98.386  1.00 9.97   ? 57  LYS B O     1 
ATOM   4319 C CB    . LYS C 3 62  ? 120.419 121.244 99.741  1.00 9.97   ? 57  LYS B CB    1 
ATOM   4320 C CG    . LYS C 3 62  ? 120.436 122.183 100.937 1.00 9.97   ? 57  LYS B CG    1 
ATOM   4321 C CD    . LYS C 3 62  ? 121.169 123.475 100.613 1.00 9.97   ? 57  LYS B CD    1 
ATOM   4322 C CE    . LYS C 3 62  ? 121.050 124.494 101.737 1.00 9.97   ? 57  LYS B CE    1 
ATOM   4323 N NZ    . LYS C 3 62  ? 121.020 123.871 103.090 1.00 9.97   ? 57  LYS B NZ    1 
ATOM   4324 N N     . ILE C 3 63  ? 119.019 118.618 98.256  1.00 7.55   ? 58  ILE B N     1 
ATOM   4325 C CA    . ILE C 3 63  ? 118.924 117.815 97.044  1.00 7.55   ? 58  ILE B CA    1 
ATOM   4326 C C     . ILE C 3 63  ? 118.865 118.770 95.862  1.00 7.55   ? 58  ILE B C     1 
ATOM   4327 O O     . ILE C 3 63  ? 117.960 119.610 95.779  1.00 7.55   ? 58  ILE B O     1 
ATOM   4328 C CB    . ILE C 3 63  ? 117.694 116.896 97.081  1.00 7.55   ? 58  ILE B CB    1 
ATOM   4329 C CG1   . ILE C 3 63  ? 117.963 115.690 97.979  1.00 7.55   ? 58  ILE B CG1   1 
ATOM   4330 C CG2   . ILE C 3 63  ? 117.328 116.429 95.684  1.00 7.55   ? 58  ILE B CG2   1 
ATOM   4331 C CD1   . ILE C 3 63  ? 116.717 115.100 98.572  1.00 7.55   ? 58  ILE B CD1   1 
ATOM   4332 N N     . TYR C 3 64  ? 119.823 118.647 94.942  1.00 10.07  ? 59  TYR B N     1 
ATOM   4333 C CA    . TYR C 3 64  ? 119.934 119.630 93.869  1.00 10.07  ? 59  TYR B CA    1 
ATOM   4334 C C     . TYR C 3 64  ? 119.351 119.142 92.552  1.00 10.07  ? 59  TYR B C     1 
ATOM   4335 O O     . TYR C 3 64  ? 118.657 119.902 91.868  1.00 10.07  ? 59  TYR B O     1 
ATOM   4336 C CB    . TYR C 3 64  ? 121.398 120.023 93.671  1.00 10.07  ? 59  TYR B CB    1 
ATOM   4337 C CG    . TYR C 3 64  ? 121.854 121.079 94.644  1.00 10.07  ? 59  TYR B CG    1 
ATOM   4338 C CD1   . TYR C 3 64  ? 121.389 122.382 94.550  1.00 10.07  ? 59  TYR B CD1   1 
ATOM   4339 C CD2   . TYR C 3 64  ? 122.735 120.770 95.669  1.00 10.07  ? 59  TYR B CD2   1 
ATOM   4340 C CE1   . TYR C 3 64  ? 121.796 123.348 95.441  1.00 10.07  ? 59  TYR B CE1   1 
ATOM   4341 C CE2   . TYR C 3 64  ? 123.147 121.729 96.563  1.00 10.07  ? 59  TYR B CE2   1 
ATOM   4342 C CZ    . TYR C 3 64  ? 122.674 123.015 96.446  1.00 10.07  ? 59  TYR B CZ    1 
ATOM   4343 O OH    . TYR C 3 64  ? 123.085 123.970 97.340  1.00 10.07  ? 59  TYR B OH    1 
ATOM   4344 N N     . ALA C 3 65  ? 119.612 117.894 92.179  1.00 7.59   ? 60  ALA B N     1 
ATOM   4345 C CA    . ALA C 3 65  ? 119.176 117.362 90.901  1.00 7.59   ? 60  ALA B CA    1 
ATOM   4346 C C     . ALA C 3 65  ? 118.549 115.992 91.099  1.00 7.59   ? 60  ALA B C     1 
ATOM   4347 O O     . ALA C 3 65  ? 118.841 115.287 92.068  1.00 7.59   ? 60  ALA B O     1 
ATOM   4348 C CB    . ALA C 3 65  ? 120.340 117.265 89.912  1.00 7.59   ? 60  ALA B CB    1 
ATOM   4349 N N     . MET C 3 66  ? 117.675 115.628 90.165  1.00 6.65   ? 61  MET B N     1 
ATOM   4350 C CA    . MET C 3 66  ? 116.985 114.351 90.202  1.00 6.65   ? 61  MET B CA    1 
ATOM   4351 C C     . MET C 3 66  ? 116.471 114.044 88.805  1.00 6.65   ? 61  MET B C     1 
ATOM   4352 O O     . MET C 3 66  ? 115.973 114.929 88.104  1.00 6.65   ? 61  MET B O     1 
ATOM   4353 C CB    . MET C 3 66  ? 115.836 114.372 91.217  1.00 6.65   ? 61  MET B CB    1 
ATOM   4354 C CG    . MET C 3 66  ? 114.956 113.133 91.206  1.00 6.65   ? 61  MET B CG    1 
ATOM   4355 S SD    . MET C 3 66  ? 113.643 113.191 89.969  1.00 6.65   ? 61  MET B SD    1 
ATOM   4356 C CE    . MET C 3 66  ? 112.740 114.634 90.514  1.00 6.65   ? 61  MET B CE    1 
ATOM   4357 N N     . HIS C 3 67  ? 116.597 112.780 88.406  1.00 6.25   ? 62  HIS B N     1 
ATOM   4358 C CA    . HIS C 3 67  ? 116.193 112.363 87.071  1.00 6.25   ? 62  HIS B CA    1 
ATOM   4359 C C     . HIS C 3 67  ? 115.596 110.967 87.138  1.00 6.25   ? 62  HIS B C     1 
ATOM   4360 O O     . HIS C 3 67  ? 116.170 110.071 87.763  1.00 6.25   ? 62  HIS B O     1 
ATOM   4361 C CB    . HIS C 3 67  ? 117.380 112.396 86.102  1.00 6.25   ? 62  HIS B CB    1 
ATOM   4362 C CG    . HIS C 3 67  ? 116.980 112.427 84.660  1.00 6.25   ? 62  HIS B CG    1 
ATOM   4363 N ND1   . HIS C 3 67  ? 117.131 111.345 83.822  1.00 6.25   ? 62  HIS B ND1   1 
ATOM   4364 C CD2   . HIS C 3 67  ? 116.412 113.403 83.914  1.00 6.25   ? 62  HIS B CD2   1 
ATOM   4365 C CE1   . HIS C 3 67  ? 116.687 111.657 82.618  1.00 6.25   ? 62  HIS B CE1   1 
ATOM   4366 N NE2   . HIS C 3 67  ? 116.244 112.900 82.647  1.00 6.25   ? 62  HIS B NE2   1 
ATOM   4367 N N     . TRP C 3 68  ? 114.444 110.796 86.500  1.00 6.99   ? 63  TRP B N     1 
ATOM   4368 C CA    . TRP C 3 68  ? 113.774 109.508 86.441  1.00 6.99   ? 63  TRP B CA    1 
ATOM   4369 C C     . TRP C 3 68  ? 114.463 108.587 85.443  1.00 6.99   ? 63  TRP B C     1 
ATOM   4370 O O     . TRP C 3 68  ? 114.960 109.023 84.402  1.00 6.99   ? 63  TRP B O     1 
ATOM   4371 C CB    . TRP C 3 68  ? 112.312 109.687 86.032  1.00 6.99   ? 63  TRP B CB    1 
ATOM   4372 C CG    . TRP C 3 68  ? 111.379 109.936 87.168  1.00 6.99   ? 63  TRP B CG    1 
ATOM   4373 C CD1   . TRP C 3 68  ? 110.778 111.115 87.484  1.00 6.99   ? 63  TRP B CD1   1 
ATOM   4374 C CD2   . TRP C 3 68  ? 110.917 108.980 88.127  1.00 6.99   ? 63  TRP B CD2   1 
ATOM   4375 N NE1   . TRP C 3 68  ? 109.979 110.960 88.588  1.00 6.99   ? 63  TRP B NE1   1 
ATOM   4376 C CE2   . TRP C 3 68  ? 110.046 109.656 89.002  1.00 6.99   ? 63  TRP B CE2   1 
ATOM   4377 C CE3   . TRP C 3 68  ? 111.158 107.619 88.334  1.00 6.99   ? 63  TRP B CE3   1 
ATOM   4378 C CZ2   . TRP C 3 68  ? 109.415 109.020 90.068  1.00 6.99   ? 63  TRP B CZ2   1 
ATOM   4379 C CZ3   . TRP C 3 68  ? 110.530 106.988 89.393  1.00 6.99   ? 63  TRP B CZ3   1 
ATOM   4380 C CH2   . TRP C 3 68  ? 109.672 107.689 90.247  1.00 6.99   ? 63  TRP B CH2   1 
ATOM   4381 N N     . GLY C 3 69  ? 114.478 107.294 85.768  1.00 7.38   ? 64  GLY B N     1 
ATOM   4382 C CA    . GLY C 3 69  ? 114.890 106.294 84.810  1.00 7.38   ? 64  GLY B CA    1 
ATOM   4383 C C     . GLY C 3 69  ? 113.807 106.032 83.782  1.00 7.38   ? 64  GLY B C     1 
ATOM   4384 O O     . GLY C 3 69  ? 112.633 106.342 83.978  1.00 7.38   ? 64  GLY B O     1 
ATOM   4385 N N     . THR C 3 70  ? 114.216 105.445 82.657  1.00 7.71   ? 65  THR B N     1 
ATOM   4386 C CA    . THR C 3 70  ? 113.280 105.221 81.562  1.00 7.71   ? 65  THR B CA    1 
ATOM   4387 C C     . THR C 3 70  ? 112.248 104.147 81.879  1.00 7.71   ? 65  THR B C     1 
ATOM   4388 O O     . THR C 3 70  ? 111.220 104.083 81.197  1.00 7.71   ? 65  THR B O     1 
ATOM   4389 C CB    . THR C 3 70  ? 114.042 104.842 80.290  1.00 7.71   ? 65  THR B CB    1 
ATOM   4390 O OG1   . THR C 3 70  ? 114.936 105.902 79.930  1.00 7.71   ? 65  THR B OG1   1 
ATOM   4391 C CG2   . THR C 3 70  ? 113.075 104.595 79.142  1.00 7.71   ? 65  THR B CG2   1 
ATOM   4392 N N     . ASP C 3 71  ? 112.485 103.316 82.890  1.00 7.55   ? 66  ASP B N     1 
ATOM   4393 C CA    . ASP C 3 71  ? 111.526 102.298 83.295  1.00 7.55   ? 66  ASP B CA    1 
ATOM   4394 C C     . ASP C 3 71  ? 110.423 102.848 84.190  1.00 7.55   ? 66  ASP B C     1 
ATOM   4395 O O     . ASP C 3 71  ? 109.501 102.105 84.537  1.00 7.55   ? 66  ASP B O     1 
ATOM   4396 C CB    . ASP C 3 71  ? 112.243 101.152 84.018  1.00 7.55   ? 66  ASP B CB    1 
ATOM   4397 C CG    . ASP C 3 71  ? 113.031 101.624 85.222  1.00 7.55   ? 66  ASP B CG    1 
ATOM   4398 O OD1   . ASP C 3 71  ? 113.377 102.821 85.277  1.00 7.55   ? 66  ASP B OD1   1 
ATOM   4399 O OD2   . ASP C 3 71  ? 113.309 100.795 86.113  1.00 7.55   ? 66  ASP B OD2   1 
ATOM   4400 N N     . SER C 3 72  ? 110.498 104.123 84.572  1.00 9.30   ? 67  SER B N     1 
ATOM   4401 C CA    . SER C 3 72  ? 109.502 104.776 85.413  1.00 9.30   ? 67  SER B CA    1 
ATOM   4402 C C     . SER C 3 72  ? 109.435 104.179 86.812  1.00 9.30   ? 67  SER B C     1 
ATOM   4403 O O     . SER C 3 72  ? 108.428 104.344 87.507  1.00 9.30   ? 67  SER B O     1 
ATOM   4404 C CB    . SER C 3 72  ? 108.116 104.723 84.763  1.00 9.30   ? 67  SER B CB    1 
ATOM   4405 O OG    . SER C 3 72  ? 108.117 105.394 83.516  1.00 9.30   ? 67  SER B OG    1 
ATOM   4406 N N     . ARG C 3 73  ? 110.487 103.485 87.243  1.00 6.58   ? 68  ARG B N     1 
ATOM   4407 C CA    . ARG C 3 73  ? 110.507 102.875 88.566  1.00 6.58   ? 68  ARG B CA    1 
ATOM   4408 C C     . ARG C 3 73  ? 111.767 103.264 89.327  1.00 6.58   ? 68  ARG B C     1 
ATOM   4409 O O     . ARG C 3 73  ? 111.749 103.361 90.557  1.00 6.58   ? 68  ARG B O     1 
ATOM   4410 C CB    . ARG C 3 73  ? 110.406 101.354 88.449  1.00 6.58   ? 68  ARG B CB    1 
ATOM   4411 C CG    . ARG C 3 73  ? 110.710 100.618 89.738  1.00 6.58   ? 68  ARG B CG    1 
ATOM   4412 C CD    . ARG C 3 73  ? 110.135 99.216  89.725  1.00 6.58   ? 68  ARG B CD    1 
ATOM   4413 N NE    . ARG C 3 73  ? 110.446 98.493  90.951  1.00 6.58   ? 68  ARG B NE    1 
ATOM   4414 C CZ    . ARG C 3 73  ? 109.924 97.321  91.286  1.00 6.58   ? 68  ARG B CZ    1 
ATOM   4415 N NH1   . ARG C 3 73  ? 109.054 96.703  90.504  1.00 6.58   ? 68  ARG B NH1   1 
ATOM   4416 N NH2   . ARG C 3 73  ? 110.286 96.755  92.432  1.00 6.58   ? 68  ARG B NH2   1 
ATOM   4417 N N     . LEU C 3 74  ? 112.860 103.494 88.609  1.00 6.22   ? 69  LEU B N     1 
ATOM   4418 C CA    . LEU C 3 74  ? 114.134 103.846 89.213  1.00 6.22   ? 69  LEU B CA    1 
ATOM   4419 C C     . LEU C 3 74  ? 114.341 105.354 89.171  1.00 6.22   ? 69  LEU B C     1 
ATOM   4420 O O     . LEU C 3 74  ? 113.933 106.037 88.228  1.00 6.22   ? 69  LEU B O     1 
ATOM   4421 C CB    . LEU C 3 74  ? 115.293 103.140 88.501  1.00 6.22   ? 69  LEU B CB    1 
ATOM   4422 C CG    . LEU C 3 74  ? 115.500 101.669 88.866  1.00 6.22   ? 69  LEU B CG    1 
ATOM   4423 C CD1   . LEU C 3 74  ? 116.316 100.963 87.797  1.00 6.22   ? 69  LEU B CD1   1 
ATOM   4424 C CD2   . LEU C 3 74  ? 116.168 101.538 90.222  1.00 6.22   ? 69  LEU B CD2   1 
ATOM   4425 N N     . LEU C 3 75  ? 114.986 105.866 90.217  1.00 6.34   ? 70  LEU B N     1 
ATOM   4426 C CA    . LEU C 3 75  ? 115.294 107.284 90.335  1.00 6.34   ? 70  LEU B CA    1 
ATOM   4427 C C     . LEU C 3 75  ? 116.774 107.445 90.625  1.00 6.34   ? 70  LEU B C     1 
ATOM   4428 O O     . LEU C 3 75  ? 117.402 106.549 91.184  1.00 6.34   ? 70  LEU B O     1 
ATOM   4429 C CB    . LEU C 3 75  ? 114.495 107.956 91.459  1.00 6.34   ? 70  LEU B CB    1 
ATOM   4430 C CG    . LEU C 3 75  ? 113.160 108.585 91.079  1.00 6.34   ? 70  LEU B CG    1 
ATOM   4431 C CD1   . LEU C 3 75  ? 112.283 108.751 92.306  1.00 6.34   ? 70  LEU B CD1   1 
ATOM   4432 C CD2   . LEU C 3 75  ? 113.381 109.920 90.393  1.00 6.34   ? 70  LEU B CD2   1 
ATOM   4433 N N     . VAL C 3 76  ? 117.325 108.593 90.246  1.00 6.02   ? 71  VAL B N     1 
ATOM   4434 C CA    . VAL C 3 76  ? 118.659 109.004 90.666  1.00 6.02   ? 71  VAL B CA    1 
ATOM   4435 C C     . VAL C 3 76  ? 118.569 110.439 91.163  1.00 6.02   ? 71  VAL B C     1 
ATOM   4436 O O     . VAL C 3 76  ? 117.977 111.295 90.497  1.00 6.02   ? 71  VAL B O     1 
ATOM   4437 C CB    . VAL C 3 76  ? 119.691 108.871 89.530  1.00 6.02   ? 71  VAL B CB    1 
ATOM   4438 C CG1   . VAL C 3 76  ? 119.477 109.937 88.465  1.00 6.02   ? 71  VAL B CG1   1 
ATOM   4439 C CG2   . VAL C 3 76  ? 121.103 108.943 90.088  1.00 6.02   ? 71  VAL B CG2   1 
ATOM   4440 N N     . SER C 3 77  ? 119.137 110.695 92.338  1.00 6.27   ? 72  SER B N     1 
ATOM   4441 C CA    . SER C 3 77  ? 119.122 112.024 92.932  1.00 6.27   ? 72  SER B CA    1 
ATOM   4442 C C     . SER C 3 77  ? 120.487 112.339 93.522  1.00 6.27   ? 72  SER B C     1 
ATOM   4443 O O     . SER C 3 77  ? 121.131 111.469 94.114  1.00 6.27   ? 72  SER B O     1 
ATOM   4444 C CB    . SER C 3 77  ? 118.050 112.134 94.019  1.00 6.27   ? 72  SER B CB    1 
ATOM   4445 O OG    . SER C 3 77  ? 118.427 111.420 95.182  1.00 6.27   ? 72  SER B OG    1 
ATOM   4446 N N     . ALA C 3 78  ? 120.917 113.589 93.374  1.00 7.29   ? 73  ALA B N     1 
ATOM   4447 C CA    . ALA C 3 78  ? 122.183 114.056 93.921  1.00 7.29   ? 73  ALA B CA    1 
ATOM   4448 C C     . ALA C 3 78  ? 121.935 115.079 95.019  1.00 7.29   ? 73  ALA B C     1 
ATOM   4449 O O     . ALA C 3 78  ? 121.072 115.958 94.887  1.00 7.29   ? 73  ALA B O     1 
ATOM   4450 C CB    . ALA C 3 78  ? 123.066 114.677 92.839  1.00 7.29   ? 73  ALA B CB    1 
ATOM   4451 N N     . SER C 3 79  ? 122.704 114.965 96.097  1.00 8.58   ? 74  SER B N     1 
ATOM   4452 C CA    . SER C 3 79  ? 122.575 115.864 97.231  1.00 8.58   ? 74  SER B CA    1 
ATOM   4453 C C     . SER C 3 79  ? 123.870 116.634 97.448  1.00 8.58   ? 74  SER B C     1 
ATOM   4454 O O     . SER C 3 79  ? 124.943 116.241 96.983  1.00 8.58   ? 74  SER B O     1 
ATOM   4455 C CB    . SER C 3 79  ? 122.205 115.101 98.506  1.00 8.58   ? 74  SER B CB    1 
ATOM   4456 O OG    . SER C 3 79  ? 122.169 115.967 99.623  1.00 8.58   ? 74  SER B OG    1 
ATOM   4457 N N     . GLN C 3 80  ? 123.748 117.748 98.171  1.00 11.04  ? 75  GLN B N     1 
ATOM   4458 C CA    . GLN C 3 80  ? 124.901 118.561 98.533  1.00 11.04  ? 75  GLN B CA    1 
ATOM   4459 C C     . GLN C 3 80  ? 125.901 117.799 99.389  1.00 11.04  ? 75  GLN B C     1 
ATOM   4460 O O     . GLN C 3 80  ? 127.057 118.222 99.487  1.00 11.04  ? 75  GLN B O     1 
ATOM   4461 C CB    . GLN C 3 80  ? 124.430 119.811 99.279  1.00 11.04  ? 75  GLN B CB    1 
ATOM   4462 C CG    . GLN C 3 80  ? 125.469 120.921 99.385  1.00 11.04  ? 75  GLN B CG    1 
ATOM   4463 C CD    . GLN C 3 80  ? 125.335 121.726 100.664 1.00 11.04  ? 75  GLN B CD    1 
ATOM   4464 O OE1   . GLN C 3 80  ? 124.644 121.321 101.599 1.00 11.04  ? 75  GLN B OE1   1 
ATOM   4465 N NE2   . GLN C 3 80  ? 125.997 122.876 100.709 1.00 11.04  ? 75  GLN B NE2   1 
ATOM   4466 N N     . ASP C 3 81  ? 125.487 116.693 100.001 1.00 8.58   ? 76  ASP B N     1 
ATOM   4467 C CA    . ASP C 3 81  ? 126.361 115.850 100.804 1.00 8.58   ? 76  ASP B CA    1 
ATOM   4468 C C     . ASP C 3 81  ? 127.311 115.004 99.962  1.00 8.58   ? 76  ASP B C     1 
ATOM   4469 O O     . ASP C 3 81  ? 127.949 114.094 100.502 1.00 8.58   ? 76  ASP B O     1 
ATOM   4470 C CB    . ASP C 3 81  ? 125.519 114.941 101.704 1.00 8.58   ? 76  ASP B CB    1 
ATOM   4471 C CG    . ASP C 3 81  ? 124.551 114.075 100.919 1.00 8.58   ? 76  ASP B CG    1 
ATOM   4472 O OD1   . ASP C 3 81  ? 124.910 113.620 99.816  1.00 8.58   ? 76  ASP B OD1   1 
ATOM   4473 O OD2   . ASP C 3 81  ? 123.423 113.853 101.404 1.00 8.58   ? 76  ASP B OD2   1 
ATOM   4474 N N     . GLY C 3 82  ? 127.419 115.276 98.663  1.00 8.70   ? 77  GLY B N     1 
ATOM   4475 C CA    . GLY C 3 82  ? 128.293 114.509 97.800  1.00 8.70   ? 77  GLY B CA    1 
ATOM   4476 C C     . GLY C 3 82  ? 127.861 113.066 97.660  1.00 8.70   ? 77  GLY B C     1 
ATOM   4477 O O     . GLY C 3 82  ? 128.683 112.152 97.772  1.00 8.70   ? 77  GLY B O     1 
ATOM   4478 N N     . LYS C 3 83  ? 126.570 112.850 97.419  1.00 7.73   ? 78  LYS B N     1 
ATOM   4479 C CA    . LYS C 3 83  ? 126.035 111.502 97.291  1.00 7.73   ? 78  LYS B CA    1 
ATOM   4480 C C     . LYS C 3 83  ? 125.009 111.467 96.170  1.00 7.73   ? 78  LYS B C     1 
ATOM   4481 O O     . LYS C 3 83  ? 124.155 112.358 96.072  1.00 7.73   ? 78  LYS B O     1 
ATOM   4482 C CB    . LYS C 3 83  ? 125.400 111.035 98.605  1.00 7.73   ? 78  LYS B CB    1 
ATOM   4483 C CG    . LYS C 3 83  ? 125.235 109.522 98.710  1.00 7.73   ? 78  LYS B CG    1 
ATOM   4484 C CD    . LYS C 3 83  ? 126.536 108.779 99.026  1.00 7.73   ? 78  LYS B CD    1 
ATOM   4485 C CE    . LYS C 3 83  ? 127.382 109.461 100.089 1.00 7.73   ? 78  LYS B CE    1 
ATOM   4486 N NZ    . LYS C 3 83  ? 128.503 108.594 100.539 1.00 7.73   ? 78  LYS B NZ    1 
ATOM   4487 N N     . LEU C 3 84  ? 125.100 110.430 95.336  1.00 6.56   ? 79  LEU B N     1 
ATOM   4488 C CA    . LEU C 3 84  ? 124.148 110.164 94.265  1.00 6.56   ? 79  LEU B CA    1 
ATOM   4489 C C     . LEU C 3 84  ? 123.449 108.850 94.591  1.00 6.56   ? 79  LEU B C     1 
ATOM   4490 O O     . LEU C 3 84  ? 124.053 107.779 94.493  1.00 6.56   ? 79  LEU B O     1 
ATOM   4491 C CB    . LEU C 3 84  ? 124.859 110.095 92.916  1.00 6.56   ? 79  LEU B CB    1 
ATOM   4492 C CG    . LEU C 3 84  ? 123.978 109.918 91.680  1.00 6.56   ? 79  LEU B CG    1 
ATOM   4493 C CD1   . LEU C 3 84  ? 123.097 111.133 91.465  1.00 6.56   ? 79  LEU B CD1   1 
ATOM   4494 C CD2   . LEU C 3 84  ? 124.841 109.638 90.457  1.00 6.56   ? 79  LEU B CD2   1 
ATOM   4495 N N     . ILE C 3 85  ? 122.186 108.929 94.983  1.00 5.84   ? 80  ILE B N     1 
ATOM   4496 C CA    . ILE C 3 85  ? 121.429 107.757 95.401  1.00 5.84   ? 80  ILE B CA    1 
ATOM   4497 C C     . ILE C 3 85  ? 120.505 107.349 94.266  1.00 5.84   ? 80  ILE B C     1 
ATOM   4498 O O     . ILE C 3 85  ? 119.764 108.180 93.724  1.00 5.84   ? 80  ILE B O     1 
ATOM   4499 C CB    . ILE C 3 85  ? 120.633 108.030 96.689  1.00 5.84   ? 80  ILE B CB    1 
ATOM   4500 C CG1   . ILE C 3 85  ? 121.589 108.216 97.869  1.00 5.84   ? 80  ILE B CG1   1 
ATOM   4501 C CG2   . ILE C 3 85  ? 119.686 106.875 96.977  1.00 5.84   ? 80  ILE B CG2   1 
ATOM   4502 C CD1   . ILE C 3 85  ? 120.911 108.667 99.145  1.00 5.84   ? 80  ILE B CD1   1 
ATOM   4503 N N     . ILE C 3 86  ? 120.565 106.073 93.896  1.00 5.86   ? 81  ILE B N     1 
ATOM   4504 C CA    . ILE C 3 86  ? 119.629 105.475 92.955  1.00 5.86   ? 81  ILE B CA    1 
ATOM   4505 C C     . ILE C 3 86  ? 118.609 104.692 93.766  1.00 5.86   ? 81  ILE B C     1 
ATOM   4506 O O     . ILE C 3 86  ? 118.961 103.722 94.452  1.00 5.86   ? 81  ILE B O     1 
ATOM   4507 C CB    . ILE C 3 86  ? 120.342 104.578 91.933  1.00 5.86   ? 81  ILE B CB    1 
ATOM   4508 C CG1   . ILE C 3 86  ? 121.294 105.414 91.072  1.00 5.86   ? 81  ILE B CG1   1 
ATOM   4509 C CG2   . ILE C 3 86  ? 119.326 103.849 91.059  1.00 5.86   ? 81  ILE B CG2   1 
ATOM   4510 C CD1   . ILE C 3 86  ? 122.230 104.602 90.216  1.00 5.86   ? 81  ILE B CD1   1 
ATOM   4511 N N     . TRP C 3 87  ? 117.351 105.113 93.656  1.00 6.13   ? 82  TRP B N     1 
ATOM   4512 C CA    . TRP C 3 87  ? 116.237 104.633 94.456  1.00 6.13   ? 82  TRP B CA    1 
ATOM   4513 C C     . TRP C 3 87  ? 115.344 103.721 93.631  1.00 6.13   ? 82  TRP B C     1 
ATOM   4514 O O     . TRP C 3 87  ? 115.157 103.929 92.427  1.00 6.13   ? 82  TRP B O     1 
ATOM   4515 C CB    . TRP C 3 87  ? 115.352 105.789 94.959  1.00 6.13   ? 82  TRP B CB    1 
ATOM   4516 C CG    . TRP C 3 87  ? 116.037 106.881 95.713  1.00 6.13   ? 82  TRP B CG    1 
ATOM   4517 C CD1   . TRP C 3 87  ? 116.667 107.967 95.184  1.00 6.13   ? 82  TRP B CD1   1 
ATOM   4518 C CD2   . TRP C 3 87  ? 116.115 107.026 97.136  1.00 6.13   ? 82  TRP B CD2   1 
ATOM   4519 N NE1   . TRP C 3 87  ? 117.154 108.768 96.186  1.00 6.13   ? 82  TRP B NE1   1 
ATOM   4520 C CE2   . TRP C 3 87  ? 116.824 108.215 97.395  1.00 6.13   ? 82  TRP B CE2   1 
ATOM   4521 C CE3   . TRP C 3 87  ? 115.661 106.263 98.215  1.00 6.13   ? 82  TRP B CE3   1 
ATOM   4522 C CZ2   . TRP C 3 87  ? 117.096 108.654 98.687  1.00 6.13   ? 82  TRP B CZ2   1 
ATOM   4523 C CZ3   . TRP C 3 87  ? 115.933 106.702 99.497  1.00 6.13   ? 82  TRP B CZ3   1 
ATOM   4524 C CH2   . TRP C 3 87  ? 116.640 107.888 99.721  1.00 6.13   ? 82  TRP B CH2   1 
ATOM   4525 N N     . ASP C 3 88  ? 114.765 102.730 94.305  1.00 6.03   ? 83  ASP B N     1 
ATOM   4526 C CA    . ASP C 3 88  ? 113.603 102.001 93.805  1.00 6.03   ? 83  ASP B CA    1 
ATOM   4527 C C     . ASP C 3 88  ? 112.378 102.699 94.385  1.00 6.03   ? 83  ASP B C     1 
ATOM   4528 O O     . ASP C 3 88  ? 112.060 102.539 95.566  1.00 6.03   ? 83  ASP B O     1 
ATOM   4529 C CB    . ASP C 3 88  ? 113.657 100.531 94.205  1.00 6.03   ? 83  ASP B CB    1 
ATOM   4530 C CG    . ASP C 3 88  ? 112.534 99.718  93.593  1.00 6.03   ? 83  ASP B CG    1 
ATOM   4531 O OD1   . ASP C 3 88  ? 111.585 100.320 93.052  1.00 6.03   ? 83  ASP B OD1   1 
ATOM   4532 O OD2   . ASP C 3 88  ? 112.595 98.474  93.659  1.00 6.03   ? 83  ASP B OD2   1 
ATOM   4533 N N     . SER C 3 89  ? 111.692 103.483 93.552  1.00 7.38   ? 84  SER B N     1 
ATOM   4534 C CA    . SER C 3 89  ? 110.583 104.288 94.052  1.00 7.38   ? 84  SER B CA    1 
ATOM   4535 C C     . SER C 3 89  ? 109.425 103.421 94.526  1.00 7.38   ? 84  SER B C     1 
ATOM   4536 O O     . SER C 3 89  ? 108.677 103.826 95.423  1.00 7.38   ? 84  SER B O     1 
ATOM   4537 C CB    . SER C 3 89  ? 110.108 105.256 92.968  1.00 7.38   ? 84  SER B CB    1 
ATOM   4538 O OG    . SER C 3 89  ? 109.424 104.572 91.935  1.00 7.38   ? 84  SER B OG    1 
ATOM   4539 N N     . TYR C 3 90  ? 109.259 102.231 93.944  1.00 7.56   ? 85  TYR B N     1 
ATOM   4540 C CA    . TYR C 3 90  ? 108.115 101.395 94.292  1.00 7.56   ? 85  TYR B CA    1 
ATOM   4541 C C     . TYR C 3 90  ? 108.131 100.992 95.758  1.00 7.56   ? 85  TYR B C     1 
ATOM   4542 O O     . TYR C 3 90  ? 107.087 101.025 96.418  1.00 7.56   ? 85  TYR B O     1 
ATOM   4543 C CB    . TYR C 3 90  ? 108.087 100.146 93.413  1.00 7.56   ? 85  TYR B CB    1 
ATOM   4544 C CG    . TYR C 3 90  ? 107.501 100.368 92.038  1.00 7.56   ? 85  TYR B CG    1 
ATOM   4545 C CD1   . TYR C 3 90  ? 107.525 101.622 91.443  1.00 7.56   ? 85  TYR B CD1   1 
ATOM   4546 C CD2   . TYR C 3 90  ? 106.925 99.322  91.334  1.00 7.56   ? 85  TYR B CD2   1 
ATOM   4547 C CE1   . TYR C 3 90  ? 106.991 101.825 90.189  1.00 7.56   ? 85  TYR B CE1   1 
ATOM   4548 C CE2   . TYR C 3 90  ? 106.388 99.516  90.080  1.00 7.56   ? 85  TYR B CE2   1 
ATOM   4549 C CZ    . TYR C 3 90  ? 106.426 100.769 89.512  1.00 7.56   ? 85  TYR B CZ    1 
ATOM   4550 O OH    . TYR C 3 90  ? 105.892 100.967 88.261  1.00 7.56   ? 85  TYR B OH    1 
ATOM   4551 N N     . THR C 3 91  ? 109.296 100.613 96.283  1.00 6.33   ? 86  THR B N     1 
ATOM   4552 C CA    . THR C 3 91  ? 109.399 100.108 97.645  1.00 6.33   ? 86  THR B CA    1 
ATOM   4553 C C     . THR C 3 91  ? 110.203 101.037 98.549  1.00 6.33   ? 86  THR B C     1 
ATOM   4554 O O     . THR C 3 91  ? 110.267 100.800 99.760  1.00 6.33   ? 86  THR B O     1 
ATOM   4555 C CB    . THR C 3 91  ? 110.030 98.710  97.636  1.00 6.33   ? 86  THR B CB    1 
ATOM   4556 O OG1   . THR C 3 91  ? 109.214 97.826  96.858  1.00 6.33   ? 86  THR B OG1   1 
ATOM   4557 C CG2   . THR C 3 91  ? 110.129 98.151  99.047  1.00 6.33   ? 86  THR B CG2   1 
ATOM   4558 N N     . THR C 3 92  ? 110.788 102.102 98.002  1.00 6.48   ? 87  THR B N     1 
ATOM   4559 C CA    . THR C 3 92  ? 111.707 102.963 98.749  1.00 6.48   ? 87  THR B CA    1 
ATOM   4560 C C     . THR C 3 92  ? 112.991 102.214 99.092  1.00 6.48   ? 87  THR B C     1 
ATOM   4561 O O     . THR C 3 92  ? 113.640 102.477 100.105 1.00 6.48   ? 87  THR B O     1 
ATOM   4562 C CB    . THR C 3 92  ? 111.054 103.515 100.019 1.00 6.48   ? 87  THR B CB    1 
ATOM   4563 O OG1   . THR C 3 92  ? 110.787 102.444 100.932 1.00 6.48   ? 87  THR B OG1   1 
ATOM   4564 C CG2   . THR C 3 92  ? 109.758 104.223 99.690  1.00 6.48   ? 87  THR B CG2   1 
ATOM   4565 N N     . ASN C 3 93  ? 113.361 101.270 98.232  1.00 5.91   ? 88  ASN B N     1 
ATOM   4566 C CA    . ASN C 3 93  ? 114.582 100.488 98.404  1.00 5.91   ? 88  ASN B CA    1 
ATOM   4567 C C     . ASN C 3 93  ? 115.725 101.255 97.753  1.00 5.91   ? 88  ASN B C     1 
ATOM   4568 O O     . ASN C 3 93  ? 115.649 101.629 96.581  1.00 5.91   ? 88  ASN B O     1 
ATOM   4569 C CB    . ASN C 3 93  ? 114.431 99.103  97.784  1.00 5.91   ? 88  ASN B CB    1 
ATOM   4570 C CG    . ASN C 3 93  ? 113.726 98.126  98.697  1.00 5.91   ? 88  ASN B CG    1 
ATOM   4571 O OD1   . ASN C 3 93  ? 112.881 97.347  98.261  1.00 5.91   ? 88  ASN B OD1   1 
ATOM   4572 N ND2   . ASN C 3 93  ? 114.060 98.174  99.978  1.00 5.91   ? 88  ASN B ND2   1 
ATOM   4573 N N     . LYS C 3 94  ? 116.793 101.489 98.511  1.00 5.97   ? 89  LYS B N     1 
ATOM   4574 C CA    . LYS C 3 94  ? 117.973 102.121 97.940  1.00 5.97   ? 89  LYS B CA    1 
ATOM   4575 C C     . LYS C 3 94  ? 118.735 101.114 97.091  1.00 5.97   ? 89  LYS B C     1 
ATOM   4576 O O     . LYS C 3 94  ? 119.341 100.179 97.621  1.00 5.97   ? 89  LYS B O     1 
ATOM   4577 C CB    . LYS C 3 94  ? 118.877 102.685 99.035  1.00 5.97   ? 89  LYS B CB    1 
ATOM   4578 C CG    . LYS C 3 94  ? 118.524 104.099 99.453  1.00 5.97   ? 89  LYS B CG    1 
ATOM   4579 C CD    . LYS C 3 94  ? 119.239 104.485 100.732 1.00 5.97   ? 89  LYS B CD    1 
ATOM   4580 C CE    . LYS C 3 94  ? 118.431 105.461 101.567 1.00 5.97   ? 89  LYS B CE    1 
ATOM   4581 N NZ    . LYS C 3 94  ? 117.148 104.875 102.050 1.00 5.97   ? 89  LYS B NZ    1 
ATOM   4582 N N     . VAL C 3 95  ? 118.706 101.294 95.770  1.00 5.39   ? 90  VAL B N     1 
ATOM   4583 C CA    . VAL C 3 95  ? 119.392 100.358 94.887  1.00 5.39   ? 90  VAL B CA    1 
ATOM   4584 C C     . VAL C 3 95  ? 120.891 100.620 94.893  1.00 5.39   ? 90  VAL B C     1 
ATOM   4585 O O     . VAL C 3 95  ? 121.694 99.688  95.018  1.00 5.39   ? 90  VAL B O     1 
ATOM   4586 C CB    . VAL C 3 95  ? 118.810 100.438 93.465  1.00 5.39   ? 90  VAL B CB    1 
ATOM   4587 C CG1   . VAL C 3 95  ? 119.368 99.320  92.603  1.00 5.39   ? 90  VAL B CG1   1 
ATOM   4588 C CG2   . VAL C 3 95  ? 117.293 100.376 93.508  1.00 5.39   ? 90  VAL B CG2   1 
ATOM   4589 N N     . HIS C 3 96  ? 121.297 101.881 94.760  1.00 5.56   ? 91  HIS B N     1 
ATOM   4590 C CA    . HIS C 3 96  ? 122.722 102.193 94.712  1.00 5.56   ? 91  HIS B CA    1 
ATOM   4591 C C     . HIS C 3 96  ? 122.996 103.477 95.479  1.00 5.56   ? 91  HIS B C     1 
ATOM   4592 O O     . HIS C 3 96  ? 122.131 104.348 95.586  1.00 5.56   ? 91  HIS B O     1 
ATOM   4593 C CB    . HIS C 3 96  ? 123.228 102.340 93.270  1.00 5.56   ? 91  HIS B CB    1 
ATOM   4594 C CG    . HIS C 3 96  ? 123.316 101.050 92.516  1.00 5.56   ? 91  HIS B CG    1 
ATOM   4595 N ND1   . HIS C 3 96  ? 124.215 100.056 92.839  1.00 5.56   ? 91  HIS B ND1   1 
ATOM   4596 C CD2   . HIS C 3 96  ? 122.626 100.598 91.442  1.00 5.56   ? 91  HIS B CD2   1 
ATOM   4597 C CE1   . HIS C 3 96  ? 124.068 99.044  92.003  1.00 5.56   ? 91  HIS B CE1   1 
ATOM   4598 N NE2   . HIS C 3 96  ? 123.111 99.347  91.146  1.00 5.56   ? 91  HIS B NE2   1 
ATOM   4599 N N     . ALA C 3 97  ? 124.220 103.588 95.991  1.00 6.32   ? 92  ALA B N     1 
ATOM   4600 C CA    . ALA C 3 97  ? 124.714 104.807 96.624  1.00 6.32   ? 92  ALA B CA    1 
ATOM   4601 C C     . ALA C 3 97  ? 126.113 105.079 96.089  1.00 6.32   ? 92  ALA B C     1 
ATOM   4602 O O     . ALA C 3 97  ? 127.071 104.402 96.478  1.00 6.32   ? 92  ALA B O     1 
ATOM   4603 C CB    . ALA C 3 97  ? 124.725 104.676 98.146  1.00 6.32   ? 92  ALA B CB    1 
ATOM   4604 N N     . ILE C 3 98  ? 126.232 106.062 95.201  1.00 6.78   ? 93  ILE B N     1 
ATOM   4605 C CA    . ILE C 3 98  ? 127.496 106.403 94.552  1.00 6.78   ? 93  ILE B CA    1 
ATOM   4606 C C     . ILE C 3 98  ? 128.084 107.606 95.286  1.00 6.78   ? 93  ILE B C     1 
ATOM   4607 O O     . ILE C 3 98  ? 127.447 108.675 95.311  1.00 6.78   ? 93  ILE B O     1 
ATOM   4608 C CB    . ILE C 3 98  ? 127.295 106.709 93.062  1.00 6.78   ? 93  ILE B CB    1 
ATOM   4609 C CG1   . ILE C 3 98  ? 126.527 105.574 92.382  1.00 6.78   ? 93  ILE B CG1   1 
ATOM   4610 C CG2   . ILE C 3 98  ? 128.632 106.914 92.374  1.00 6.78   ? 93  ILE B CG2   1 
ATOM   4611 C CD1   . ILE C 3 98  ? 125.087 105.907 92.087  1.00 6.78   ? 93  ILE B CD1   1 
ATOM   4612 N N     . PRO C 3 99  ? 129.261 107.486 95.903  1.00 7.60   ? 94  PRO B N     1 
ATOM   4613 C CA    . PRO C 3 99  ? 129.919 108.671 96.474  1.00 7.60   ? 94  PRO B CA    1 
ATOM   4614 C C     . PRO C 3 99  ? 130.592 109.488 95.381  1.00 7.60   ? 94  PRO B C     1 
ATOM   4615 O O     . PRO C 3 99  ? 131.581 109.056 94.786  1.00 7.60   ? 94  PRO B O     1 
ATOM   4616 C CB    . PRO C 3 99  ? 130.939 108.073 97.448  1.00 7.60   ? 94  PRO B CB    1 
ATOM   4617 C CG    . PRO C 3 99  ? 131.254 106.740 96.873  1.00 7.60   ? 94  PRO B CG    1 
ATOM   4618 C CD    . PRO C 3 99  ? 129.982 106.246 96.241  1.00 7.60   ? 94  PRO B CD    1 
ATOM   4619 N N     . LEU C 3 100 ? 130.050 110.674 95.119  1.00 8.30   ? 95  LEU B N     1 
ATOM   4620 C CA    . LEU C 3 100 ? 130.600 111.546 94.094  1.00 8.30   ? 95  LEU B CA    1 
ATOM   4621 C C     . LEU C 3 100 ? 131.950 112.101 94.530  1.00 8.30   ? 95  LEU B C     1 
ATOM   4622 O O     . LEU C 3 100 ? 132.227 112.257 95.722  1.00 8.30   ? 95  LEU B O     1 
ATOM   4623 C CB    . LEU C 3 100 ? 129.639 112.695 93.793  1.00 8.30   ? 95  LEU B CB    1 
ATOM   4624 C CG    . LEU C 3 100 ? 128.230 112.278 93.370  1.00 8.30   ? 95  LEU B CG    1 
ATOM   4625 C CD1   . LEU C 3 100 ? 127.271 113.449 93.476  1.00 8.30   ? 95  LEU B CD1   1 
ATOM   4626 C CD2   . LEU C 3 100 ? 128.243 111.718 91.959  1.00 8.30   ? 95  LEU B CD2   1 
ATOM   4627 N N     . ARG C 3 101 ? 132.795 112.400 93.543  1.00 11.29  ? 96  ARG B N     1 
ATOM   4628 C CA    . ARG C 3 101 ? 134.135 112.895 93.837  1.00 11.29  ? 96  ARG B CA    1 
ATOM   4629 C C     . ARG C 3 101 ? 134.100 114.334 94.339  1.00 11.29  ? 96  ARG B C     1 
ATOM   4630 O O     . ARG C 3 101 ? 134.927 114.723 95.171  1.00 11.29  ? 96  ARG B O     1 
ATOM   4631 C CB    . ARG C 3 101 ? 135.017 112.784 92.594  1.00 11.29  ? 96  ARG B CB    1 
ATOM   4632 C CG    . ARG C 3 101 ? 136.503 112.930 92.873  1.00 11.29  ? 96  ARG B CG    1 
ATOM   4633 C CD    . ARG C 3 101 ? 137.333 112.601 91.642  1.00 11.29  ? 96  ARG B CD    1 
ATOM   4634 N NE    . ARG C 3 101 ? 137.670 111.182 91.568  1.00 11.29  ? 96  ARG B NE    1 
ATOM   4635 C CZ    . ARG C 3 101 ? 137.047 110.293 90.804  1.00 11.29  ? 96  ARG B CZ    1 
ATOM   4636 N NH1   . ARG C 3 101 ? 136.025 110.631 90.033  1.00 11.29  ? 96  ARG B NH1   1 
ATOM   4637 N NH2   . ARG C 3 101 ? 137.459 109.028 90.814  1.00 11.29  ? 96  ARG B NH2   1 
ATOM   4638 N N     . SER C 3 102 ? 133.159 115.135 93.845  1.00 12.28  ? 97  SER B N     1 
ATOM   4639 C CA    . SER C 3 102 ? 132.969 116.509 94.289  1.00 12.28  ? 97  SER B CA    1 
ATOM   4640 C C     . SER C 3 102 ? 131.592 116.641 94.923  1.00 12.28  ? 97  SER B C     1 
ATOM   4641 O O     . SER C 3 102 ? 130.588 116.239 94.325  1.00 12.28  ? 97  SER B O     1 
ATOM   4642 C CB    . SER C 3 102 ? 133.105 117.490 93.124  1.00 12.28  ? 97  SER B CB    1 
ATOM   4643 O OG    . SER C 3 102 ? 131.932 117.500 92.331  1.00 12.28  ? 97  SER B OG    1 
ATOM   4644 N N     . SER C 3 103 ? 131.547 117.210 96.129  1.00 11.81  ? 98  SER B N     1 
ATOM   4645 C CA    . SER C 3 103 ? 130.285 117.330 96.847  1.00 11.81  ? 98  SER B CA    1 
ATOM   4646 C C     . SER C 3 103 ? 129.392 118.427 96.282  1.00 11.81  ? 98  SER B C     1 
ATOM   4647 O O     . SER C 3 103 ? 128.212 118.491 96.639  1.00 11.81  ? 98  SER B O     1 
ATOM   4648 C CB    . SER C 3 103 ? 130.552 117.587 98.331  1.00 11.81  ? 98  SER B CB    1 
ATOM   4649 O OG    . SER C 3 103 ? 131.230 118.814 98.527  1.00 11.81  ? 98  SER B OG    1 
ATOM   4650 N N     . TRP C 3 104 ? 129.923 119.286 95.413  1.00 14.57  ? 99  TRP B N     1 
ATOM   4651 C CA    . TRP C 3 104 ? 129.153 120.391 94.840  1.00 14.57  ? 99  TRP B CA    1 
ATOM   4652 C C     . TRP C 3 104 ? 128.615 119.975 93.472  1.00 14.57  ? 99  TRP B C     1 
ATOM   4653 O O     . TRP C 3 104 ? 129.161 120.298 92.418  1.00 14.57  ? 99  TRP B O     1 
ATOM   4654 C CB    . TRP C 3 104 ? 130.016 121.642 94.758  1.00 14.57  ? 99  TRP B CB    1 
ATOM   4655 C CG    . TRP C 3 104 ? 130.784 121.871 96.011  1.00 14.57  ? 99  TRP B CG    1 
ATOM   4656 C CD1   . TRP C 3 104 ? 132.093 121.577 96.232  1.00 14.57  ? 99  TRP B CD1   1 
ATOM   4657 C CD2   . TRP C 3 104 ? 130.284 122.430 97.229  1.00 14.57  ? 99  TRP B CD2   1 
ATOM   4658 N NE1   . TRP C 3 104 ? 132.445 121.922 97.514  1.00 14.57  ? 99  TRP B NE1   1 
ATOM   4659 C CE2   . TRP C 3 104 ? 131.350 122.448 98.146  1.00 14.57  ? 99  TRP B CE2   1 
ATOM   4660 C CE3   . TRP C 3 104 ? 129.039 122.918 97.632  1.00 14.57  ? 99  TRP B CE3   1 
ATOM   4661 C CZ2   . TRP C 3 104 ? 131.211 122.937 99.440  1.00 14.57  ? 99  TRP B CZ2   1 
ATOM   4662 C CZ3   . TRP C 3 104 ? 128.903 123.403 98.916  1.00 14.57  ? 99  TRP B CZ3   1 
ATOM   4663 C CH2   . TRP C 3 104 ? 129.982 123.409 99.806  1.00 14.57  ? 99  TRP B CH2   1 
ATOM   4664 N N     . VAL C 3 105 ? 127.511 119.236 93.519  1.00 10.48  ? 100 VAL B N     1 
ATOM   4665 C CA    . VAL C 3 105 ? 126.889 118.652 92.337  1.00 10.48  ? 100 VAL B CA    1 
ATOM   4666 C C     . VAL C 3 105 ? 125.540 119.321 92.119  1.00 10.48  ? 100 VAL B C     1 
ATOM   4667 O O     . VAL C 3 105 ? 124.728 119.416 93.047  1.00 10.48  ? 100 VAL B O     1 
ATOM   4668 C CB    . VAL C 3 105 ? 126.739 117.129 92.491  1.00 10.48  ? 100 VAL B CB    1 
ATOM   4669 C CG1   . VAL C 3 105 ? 125.780 116.797 93.621  1.00 10.48  ? 100 VAL B CG1   1 
ATOM   4670 C CG2   . VAL C 3 105 ? 126.272 116.506 91.189  1.00 10.48  ? 100 VAL B CG2   1 
ATOM   4671 N N     . MET C 3 106 ? 125.298 119.785 90.892  1.00 12.03  ? 101 MET B N     1 
ATOM   4672 C CA    . MET C 3 106 ? 124.109 120.560 90.578  1.00 12.03  ? 101 MET B CA    1 
ATOM   4673 C C     . MET C 3 106 ? 123.203 119.923 89.535  1.00 12.03  ? 101 MET B C     1 
ATOM   4674 O O     . MET C 3 106 ? 122.107 120.445 89.304  1.00 12.03  ? 101 MET B O     1 
ATOM   4675 C CB    . MET C 3 106 ? 124.506 121.960 90.084  1.00 12.03  ? 101 MET B CB    1 
ATOM   4676 C CG    . MET C 3 106 ? 125.239 122.796 91.122  1.00 12.03  ? 101 MET B CG    1 
ATOM   4677 S SD    . MET C 3 106 ? 126.123 124.189 90.397  1.00 12.03  ? 101 MET B SD    1 
ATOM   4678 C CE    . MET C 3 106 ? 124.776 125.086 89.633  1.00 12.03  ? 101 MET B CE    1 
ATOM   4679 N N     . THR C 3 107 ? 123.614 118.824 88.903  1.00 10.85  ? 102 THR B N     1 
ATOM   4680 C CA    . THR C 3 107 ? 122.815 118.215 87.849  1.00 10.85  ? 102 THR B CA    1 
ATOM   4681 C C     . THR C 3 107 ? 122.931 116.699 87.917  1.00 10.85  ? 102 THR B C     1 
ATOM   4682 O O     . THR C 3 107 ? 123.934 116.155 88.387  1.00 10.85  ? 102 THR B O     1 
ATOM   4683 C CB    . THR C 3 107 ? 123.242 118.707 86.461  1.00 10.85  ? 102 THR B CB    1 
ATOM   4684 O OG1   . THR C 3 107 ? 122.467 118.037 85.461  1.00 10.85  ? 102 THR B OG1   1 
ATOM   4685 C CG2   . THR C 3 107 ? 124.721 118.446 86.221  1.00 10.85  ? 102 THR B CG2   1 
ATOM   4686 N N     . CYS C 3 108 ? 121.883 116.027 87.440  1.00 8.08   ? 103 CYS B N     1 
ATOM   4687 C CA    . CYS C 3 108 ? 121.838 114.576 87.332  1.00 8.08   ? 103 CYS B CA    1 
ATOM   4688 C C     . CYS C 3 108 ? 121.255 114.190 85.984  1.00 8.08   ? 103 CYS B C     1 
ATOM   4689 O O     . CYS C 3 108 ? 120.429 114.916 85.425  1.00 8.08   ? 103 CYS B O     1 
ATOM   4690 C CB    . CYS C 3 108 ? 120.983 113.939 88.434  1.00 8.08   ? 103 CYS B CB    1 
ATOM   4691 S SG    . CYS C 3 108 ? 121.735 113.900 90.055  1.00 8.08   ? 103 CYS B SG    1 
ATOM   4692 N N     . ALA C 3 109 ? 121.682 113.041 85.473  1.00 7.86   ? 104 ALA B N     1 
ATOM   4693 C CA    . ALA C 3 109 ? 121.077 112.434 84.301  1.00 7.86   ? 104 ALA B CA    1 
ATOM   4694 C C     . ALA C 3 109 ? 121.103 110.922 84.459  1.00 7.86   ? 104 ALA B C     1 
ATOM   4695 O O     . ALA C 3 109 ? 122.027 110.348 85.042  1.00 7.86   ? 104 ALA B O     1 
ATOM   4696 C CB    . ALA C 3 109 ? 121.796 112.852 83.013  1.00 7.86   ? 104 ALA B CB    1 
ATOM   4697 N N     . TYR C 3 110 ? 120.068 110.276 83.931  1.00 6.97   ? 105 TYR B N     1 
ATOM   4698 C CA    . TYR C 3 110 ? 119.953 108.825 83.939  1.00 6.97   ? 105 TYR B CA    1 
ATOM   4699 C C     . TYR C 3 110 ? 119.941 108.368 82.489  1.00 6.97   ? 105 TYR B C     1 
ATOM   4700 O O     . TYR C 3 110 ? 119.101 108.818 81.703  1.00 6.97   ? 105 TYR B O     1 
ATOM   4701 C CB    . TYR C 3 110 ? 118.685 108.375 84.668  1.00 6.97   ? 105 TYR B CB    1 
ATOM   4702 C CG    . TYR C 3 110 ? 118.762 106.971 85.222  1.00 6.97   ? 105 TYR B CG    1 
ATOM   4703 C CD1   . TYR C 3 110 ? 118.595 105.864 84.406  1.00 6.97   ? 105 TYR B CD1   1 
ATOM   4704 C CD2   . TYR C 3 110 ? 119.027 106.757 86.568  1.00 6.97   ? 105 TYR B CD2   1 
ATOM   4705 C CE1   . TYR C 3 110 ? 118.675 104.584 84.919  1.00 6.97   ? 105 TYR B CE1   1 
ATOM   4706 C CE2   . TYR C 3 110 ? 119.105 105.484 87.088  1.00 6.97   ? 105 TYR B CE2   1 
ATOM   4707 C CZ    . TYR C 3 110 ? 118.931 104.401 86.260  1.00 6.97   ? 105 TYR B CZ    1 
ATOM   4708 O OH    . TYR C 3 110 ? 119.011 103.129 86.776  1.00 6.97   ? 105 TYR B OH    1 
ATOM   4709 N N     . ALA C 3 111 ? 120.870 107.487 82.135  1.00 6.89   ? 106 ALA B N     1 
ATOM   4710 C CA    . ALA C 3 111 ? 121.025 107.107 80.740  1.00 6.89   ? 106 ALA B CA    1 
ATOM   4711 C C     . ALA C 3 111 ? 119.753 106.429 80.237  1.00 6.89   ? 106 ALA B C     1 
ATOM   4712 O O     . ALA C 3 111 ? 119.154 105.622 80.957  1.00 6.89   ? 106 ALA B O     1 
ATOM   4713 C CB    . ALA C 3 111 ? 122.222 106.171 80.570  1.00 6.89   ? 106 ALA B CB    1 
ATOM   4714 N N     . PRO C 3 112 ? 119.310 106.723 79.011  1.00 7.26   ? 107 PRO B N     1 
ATOM   4715 C CA    . PRO C 3 112 ? 118.074 106.093 78.514  1.00 7.26   ? 107 PRO B CA    1 
ATOM   4716 C C     . PRO C 3 112 ? 118.133 104.577 78.501  1.00 7.26   ? 107 PRO B C     1 
ATOM   4717 O O     . PRO C 3 112 ? 117.100 103.930 78.710  1.00 7.26   ? 107 PRO B O     1 
ATOM   4718 C CB    . PRO C 3 112 ? 117.922 106.658 77.094  1.00 7.26   ? 107 PRO B CB    1 
ATOM   4719 C CG    . PRO C 3 112 ? 118.839 107.818 77.010  1.00 7.26   ? 107 PRO B CG    1 
ATOM   4720 C CD    . PRO C 3 112 ? 119.912 107.637 78.025  1.00 7.26   ? 107 PRO B CD    1 
ATOM   4721 N N     . SER C 3 113 ? 119.303 103.990 78.258  1.00 7.82   ? 108 SER B N     1 
ATOM   4722 C CA    . SER C 3 113 ? 119.460 102.545 78.341  1.00 7.82   ? 108 SER B CA    1 
ATOM   4723 C C     . SER C 3 113 ? 119.403 102.040 79.773  1.00 7.82   ? 108 SER B C     1 
ATOM   4724 O O     . SER C 3 113 ? 118.965 100.908 80.008  1.00 7.82   ? 108 SER B O     1 
ATOM   4725 C CB    . SER C 3 113 ? 120.786 102.121 77.708  1.00 7.82   ? 108 SER B CB    1 
ATOM   4726 O OG    . SER C 3 113 ? 121.878 102.761 78.344  1.00 7.82   ? 108 SER B OG    1 
ATOM   4727 N N     . GLY C 3 114 ? 119.831 102.855 80.732  1.00 6.48   ? 109 GLY B N     1 
ATOM   4728 C CA    . GLY C 3 114 ? 119.838 102.474 82.125  1.00 6.48   ? 109 GLY B CA    1 
ATOM   4729 C C     . GLY C 3 114 ? 121.159 101.954 82.640  1.00 6.48   ? 109 GLY B C     1 
ATOM   4730 O O     . GLY C 3 114 ? 121.215 101.495 83.785  1.00 6.48   ? 109 GLY B O     1 
ATOM   4731 N N     . ASN C 3 115 ? 122.220 102.012 81.837  1.00 7.08   ? 110 ASN B N     1 
ATOM   4732 C CA    . ASN C 3 115 ? 123.517 101.489 82.241  1.00 7.08   ? 110 ASN B CA    1 
ATOM   4733 C C     . ASN C 3 115 ? 124.420 102.540 82.870  1.00 7.08   ? 110 ASN B C     1 
ATOM   4734 O O     . ASN C 3 115 ? 125.408 102.175 83.516  1.00 7.08   ? 110 ASN B O     1 
ATOM   4735 C CB    . ASN C 3 115 ? 124.240 100.882 81.034  1.00 7.08   ? 110 ASN B CB    1 
ATOM   4736 C CG    . ASN C 3 115 ? 123.383 99.889  80.278  1.00 7.08   ? 110 ASN B CG    1 
ATOM   4737 O OD1   . ASN C 3 115 ? 122.416 99.348  80.813  1.00 7.08   ? 110 ASN B OD1   1 
ATOM   4738 N ND2   . ASN C 3 115 ? 123.731 99.646  79.021  1.00 7.08   ? 110 ASN B ND2   1 
ATOM   4739 N N     . TYR C 3 116 ? 124.109 103.824 82.704  1.00 7.58   ? 111 TYR B N     1 
ATOM   4740 C CA    . TYR C 3 116 ? 125.003 104.895 83.116  1.00 7.58   ? 111 TYR B CA    1 
ATOM   4741 C C     . TYR C 3 116 ? 124.214 105.990 83.818  1.00 7.58   ? 111 TYR B C     1 
ATOM   4742 O O     . TYR C 3 116 ? 123.010 106.152 83.607  1.00 7.58   ? 111 TYR B O     1 
ATOM   4743 C CB    . TYR C 3 116 ? 125.751 105.493 81.916  1.00 7.58   ? 111 TYR B CB    1 
ATOM   4744 C CG    . TYR C 3 116 ? 126.690 104.531 81.227  1.00 7.58   ? 111 TYR B CG    1 
ATOM   4745 C CD1   . TYR C 3 116 ? 127.918 104.212 81.785  1.00 7.58   ? 111 TYR B CD1   1 
ATOM   4746 C CD2   . TYR C 3 116 ? 126.347 103.942 80.018  1.00 7.58   ? 111 TYR B CD2   1 
ATOM   4747 C CE1   . TYR C 3 116 ? 128.778 103.335 81.162  1.00 7.58   ? 111 TYR B CE1   1 
ATOM   4748 C CE2   . TYR C 3 116 ? 127.201 103.062 79.387  1.00 7.58   ? 111 TYR B CE2   1 
ATOM   4749 C CZ    . TYR C 3 116 ? 128.416 102.763 79.963  1.00 7.58   ? 111 TYR B CZ    1 
ATOM   4750 O OH    . TYR C 3 116 ? 129.275 101.887 79.340  1.00 7.58   ? 111 TYR B OH    1 
ATOM   4751 N N     . VAL C 3 117 ? 124.916 106.744 84.662  1.00 7.34   ? 112 VAL B N     1 
ATOM   4752 C CA    . VAL C 3 117 ? 124.367 107.949 85.280  1.00 7.34   ? 112 VAL B CA    1 
ATOM   4753 C C     . VAL C 3 117 ? 125.417 109.048 85.200  1.00 7.34   ? 112 VAL B C     1 
ATOM   4754 O O     . VAL C 3 117 ? 126.606 108.790 85.400  1.00 7.34   ? 112 VAL B O     1 
ATOM   4755 C CB    . VAL C 3 117 ? 123.937 107.720 86.744  1.00 7.34   ? 112 VAL B CB    1 
ATOM   4756 C CG1   . VAL C 3 117 ? 122.649 106.916 86.801  1.00 7.34   ? 112 VAL B CG1   1 
ATOM   4757 C CG2   . VAL C 3 117 ? 125.040 107.034 87.533  1.00 7.34   ? 112 VAL B CG2   1 
ATOM   4758 N N     . ALA C 3 118 ? 124.983 110.273 84.920  1.00 8.78   ? 113 ALA B N     1 
ATOM   4759 C CA    . ALA C 3 118 ? 125.889 111.406 84.799  1.00 8.78   ? 113 ALA B CA    1 
ATOM   4760 C C     . ALA C 3 118 ? 125.599 112.455 85.867  1.00 8.78   ? 113 ALA B C     1 
ATOM   4761 O O     . ALA C 3 118 ? 124.453 112.678 86.264  1.00 8.78   ? 113 ALA B O     1 
ATOM   4762 C CB    . ALA C 3 118 ? 125.786 112.036 83.408  1.00 8.78   ? 113 ALA B CB    1 
ATOM   4763 N N     . CYS C 3 119 ? 126.668 113.100 86.330  1.00 10.28  ? 114 CYS B N     1 
ATOM   4764 C CA    . CYS C 3 119 ? 126.566 114.129 87.358  1.00 10.28  ? 114 CYS B CA    1 
ATOM   4765 C C     . CYS C 3 119 ? 127.708 115.120 87.185  1.00 10.28  ? 114 CYS B C     1 
ATOM   4766 O O     . CYS C 3 119 ? 128.590 114.944 86.345  1.00 10.28  ? 114 CYS B O     1 
ATOM   4767 C CB    . CYS C 3 119 ? 126.592 113.526 88.764  1.00 10.28  ? 114 CYS B CB    1 
ATOM   4768 S SG    . CYS C 3 119 ? 125.065 112.710 89.246  1.00 10.28  ? 114 CYS B SG    1 
ATOM   4769 N N     . GLY C 3 120 ? 127.668 116.170 87.983  1.00 11.52  ? 115 GLY B N     1 
ATOM   4770 C CA    . GLY C 3 120 ? 128.721 117.164 88.018  1.00 11.52  ? 115 GLY B CA    1 
ATOM   4771 C C     . GLY C 3 120 ? 128.198 118.483 88.546  1.00 11.52  ? 115 GLY B C     1 
ATOM   4772 O O     . GLY C 3 120 ? 127.018 118.654 88.843  1.00 11.52  ? 115 GLY B O     1 
ATOM   4773 N N     . GLY C 3 121 ? 129.107 119.443 88.678  1.00 13.01  ? 116 GLY B N     1 
ATOM   4774 C CA    . GLY C 3 121 ? 128.757 120.716 89.278  1.00 13.01  ? 116 GLY B CA    1 
ATOM   4775 C C     . GLY C 3 121 ? 129.865 121.746 89.217  1.00 13.01  ? 116 GLY B C     1 
ATOM   4776 O O     . GLY C 3 121 ? 130.488 121.943 88.170  1.00 13.01  ? 116 GLY B O     1 
ATOM   4777 N N     . LEU C 3 122 ? 130.113 122.414 90.342  1.00 15.51  ? 117 LEU B N     1 
ATOM   4778 C CA    . LEU C 3 122 ? 131.112 123.472 90.428  1.00 15.51  ? 117 LEU B CA    1 
ATOM   4779 C C     . LEU C 3 122 ? 132.522 122.996 90.102  1.00 15.51  ? 117 LEU B C     1 
ATOM   4780 O O     . LEU C 3 122 ? 133.443 123.819 90.085  1.00 15.51  ? 117 LEU B O     1 
ATOM   4781 C CB    . LEU C 3 122 ? 131.104 124.082 91.833  1.00 15.51  ? 117 LEU B CB    1 
ATOM   4782 C CG    . LEU C 3 122 ? 129.795 124.714 92.314  1.00 15.51  ? 117 LEU B CG    1 
ATOM   4783 C CD1   . LEU C 3 122 ? 129.966 125.290 93.710  1.00 15.51  ? 117 LEU B CD1   1 
ATOM   4784 C CD2   . LEU C 3 122 ? 129.315 125.783 91.351  1.00 15.51  ? 117 LEU B CD2   1 
ATOM   4785 N N     . ASP C 3 123 ? 132.720 121.702 89.852  1.00 14.05  ? 118 ASP B N     1 
ATOM   4786 C CA    . ASP C 3 123 ? 134.018 121.173 89.461  1.00 14.05  ? 118 ASP B CA    1 
ATOM   4787 C C     . ASP C 3 123 ? 134.274 121.267 87.962  1.00 14.05  ? 118 ASP B C     1 
ATOM   4788 O O     . ASP C 3 123 ? 135.371 120.916 87.516  1.00 14.05  ? 118 ASP B O     1 
ATOM   4789 C CB    . ASP C 3 123 ? 134.144 119.714 89.913  1.00 14.05  ? 118 ASP B CB    1 
ATOM   4790 C CG    . ASP C 3 123 ? 133.112 118.808 89.266  1.00 14.05  ? 118 ASP B CG    1 
ATOM   4791 O OD1   . ASP C 3 123 ? 131.947 119.233 89.125  1.00 14.05  ? 118 ASP B OD1   1 
ATOM   4792 O OD2   . ASP C 3 123 ? 133.461 117.662 88.912  1.00 14.05  ? 118 ASP B OD2   1 
ATOM   4793 N N     . ASN C 3 124 ? 133.299 121.731 87.180  1.00 14.47  ? 119 ASN B N     1 
ATOM   4794 C CA    . ASN C 3 124 ? 133.433 121.920 85.739  1.00 14.47  ? 119 ASN B CA    1 
ATOM   4795 C C     . ASN C 3 124 ? 133.659 120.612 84.993  1.00 14.47  ? 119 ASN B C     1 
ATOM   4796 O O     . ASN C 3 124 ? 134.248 120.611 83.908  1.00 14.47  ? 119 ASN B O     1 
ATOM   4797 C CB    . ASN C 3 124 ? 134.569 122.898 85.412  1.00 14.47  ? 119 ASN B CB    1 
ATOM   4798 C CG    . ASN C 3 124 ? 134.305 124.293 85.933  1.00 14.47  ? 119 ASN B CG    1 
ATOM   4799 O OD1   . ASN C 3 124 ? 133.161 124.673 86.170  1.00 14.47  ? 119 ASN B OD1   1 
ATOM   4800 N ND2   . ASN C 3 124 ? 135.367 125.065 86.117  1.00 14.47  ? 119 ASN B ND2   1 
ATOM   4801 N N     . ILE C 3 125 ? 133.199 119.495 85.549  1.00 12.43  ? 120 ILE B N     1 
ATOM   4802 C CA    . ILE C 3 125 ? 133.401 118.181 84.957  1.00 12.43  ? 120 ILE B CA    1 
ATOM   4803 C C     . ILE C 3 125 ? 132.080 117.429 84.973  1.00 12.43  ? 120 ILE B C     1 
ATOM   4804 O O     . ILE C 3 125 ? 131.301 117.524 85.926  1.00 12.43  ? 120 ILE B O     1 
ATOM   4805 C CB    . ILE C 3 125 ? 134.487 117.377 85.704  1.00 12.43  ? 120 ILE B CB    1 
ATOM   4806 C CG1   . ILE C 3 125 ? 135.858 118.026 85.515  1.00 12.43  ? 120 ILE B CG1   1 
ATOM   4807 C CG2   . ILE C 3 125 ? 134.511 115.939 85.220  1.00 12.43  ? 120 ILE B CG2   1 
ATOM   4808 C CD1   . ILE C 3 125 ? 136.854 117.653 86.588  1.00 12.43  ? 120 ILE B CD1   1 
ATOM   4809 N N     . CYS C 3 126 ? 131.828 116.680 83.905  1.00 10.92  ? 121 CYS B N     1 
ATOM   4810 C CA    . CYS C 3 126 ? 130.668 115.795 83.818  1.00 10.92  ? 121 CYS B CA    1 
ATOM   4811 C C     . CYS C 3 126 ? 131.167 114.365 84.001  1.00 10.92  ? 121 CYS B C     1 
ATOM   4812 O O     . CYS C 3 126 ? 131.750 113.780 83.087  1.00 10.92  ? 121 CYS B O     1 
ATOM   4813 C CB    . CYS C 3 126 ? 129.937 115.969 82.491  1.00 10.92  ? 121 CYS B CB    1 
ATOM   4814 S SG    . CYS C 3 126 ? 128.325 115.160 82.429  1.00 10.92  ? 121 CYS B SG    1 
ATOM   4815 N N     . SER C 3 127 ? 130.956 113.816 85.192  1.00 9.57   ? 122 SER B N     1 
ATOM   4816 C CA    . SER C 3 127 ? 131.345 112.445 85.470  1.00 9.57   ? 122 SER B CA    1 
ATOM   4817 C C     . SER C 3 127 ? 130.228 111.489 85.077  1.00 9.57   ? 122 SER B C     1 
ATOM   4818 O O     . SER C 3 127 ? 129.047 111.732 85.342  1.00 9.57   ? 122 SER B O     1 
ATOM   4819 C CB    . SER C 3 127 ? 131.682 112.272 86.951  1.00 9.57   ? 122 SER B CB    1 
ATOM   4820 O OG    . SER C 3 127 ? 132.875 112.958 87.286  1.00 9.57   ? 122 SER B OG    1 
ATOM   4821 N N     . ILE C 3 128 ? 130.617 110.388 84.437  1.00 9.82   ? 123 ILE B N     1 
ATOM   4822 C CA    . ILE C 3 128 ? 129.696 109.364 83.965  1.00 9.82   ? 123 ILE B CA    1 
ATOM   4823 C C     . ILE C 3 128 ? 130.084 108.055 84.636  1.00 9.82   ? 123 ILE B C     1 
ATOM   4824 O O     . ILE C 3 128 ? 131.220 107.586 84.475  1.00 9.82   ? 123 ILE B O     1 
ATOM   4825 C CB    . ILE C 3 128 ? 129.727 109.225 82.435  1.00 9.82   ? 123 ILE B CB    1 
ATOM   4826 C CG1   . ILE C 3 128 ? 129.336 110.558 81.788  1.00 9.82   ? 123 ILE B CG1   1 
ATOM   4827 C CG2   . ILE C 3 128 ? 128.803 108.100 81.987  1.00 9.82   ? 123 ILE B CG2   1 
ATOM   4828 C CD1   . ILE C 3 128 ? 129.226 110.514 80.285  1.00 9.82   ? 123 ILE B CD1   1 
ATOM   4829 N N     . TYR C 3 129 ? 129.140 107.471 85.372  1.00 8.55   ? 124 TYR B N     1 
ATOM   4830 C CA    . TYR C 3 129 ? 129.336 106.263 86.157  1.00 8.55   ? 124 TYR B CA    1 
ATOM   4831 C C     . TYR C 3 129 ? 128.592 105.106 85.506  1.00 8.55   ? 124 TYR B C     1 
ATOM   4832 O O     . TYR C 3 129 ? 127.444 105.261 85.073  1.00 8.55   ? 124 TYR B O     1 
ATOM   4833 C CB    . TYR C 3 129 ? 128.818 106.443 87.588  1.00 8.55   ? 124 TYR B CB    1 
ATOM   4834 C CG    . TYR C 3 129 ? 129.472 107.559 88.369  1.00 8.55   ? 124 TYR B CG    1 
ATOM   4835 C CD1   . TYR C 3 129 ? 129.129 108.885 88.144  1.00 8.55   ? 124 TYR B CD1   1 
ATOM   4836 C CD2   . TYR C 3 129 ? 130.423 107.286 89.341  1.00 8.55   ? 124 TYR B CD2   1 
ATOM   4837 C CE1   . TYR C 3 129 ? 129.720 109.906 88.857  1.00 8.55   ? 124 TYR B CE1   1 
ATOM   4838 C CE2   . TYR C 3 129 ? 131.017 108.300 90.061  1.00 8.55   ? 124 TYR B CE2   1 
ATOM   4839 C CZ    . TYR C 3 129 ? 130.666 109.608 89.815  1.00 8.55   ? 124 TYR B CZ    1 
ATOM   4840 O OH    . TYR C 3 129 ? 131.261 110.620 90.533  1.00 8.55   ? 124 TYR B OH    1 
ATOM   4841 N N     . ASN C 3 130 ? 129.246 103.945 85.462  1.00 8.76   ? 125 ASN B N     1 
ATOM   4842 C CA    . ASN C 3 130 ? 128.683 102.740 84.863  1.00 8.76   ? 125 ASN B CA    1 
ATOM   4843 C C     . ASN C 3 130 ? 127.983 101.911 85.935  1.00 8.76   ? 125 ASN B C     1 
ATOM   4844 O O     . ASN C 3 130 ? 128.595 101.547 86.944  1.00 8.76   ? 125 ASN B O     1 
ATOM   4845 C CB    . ASN C 3 130 ? 129.782 101.921 84.185  1.00 8.76   ? 125 ASN B CB    1 
ATOM   4846 C CG    . ASN C 3 130 ? 129.241 100.708 83.457  1.00 8.76   ? 125 ASN B CG    1 
ATOM   4847 O OD1   . ASN C 3 130 ? 128.047 100.618 83.176  1.00 8.76   ? 125 ASN B OD1   1 
ATOM   4848 N ND2   . ASN C 3 130 ? 130.121 99.766  83.147  1.00 8.76   ? 125 ASN B ND2   1 
ATOM   4849 N N     . LEU C 3 131 ? 126.706 101.607 85.708  1.00 7.17   ? 126 LEU B N     1 
ATOM   4850 C CA    . LEU C 3 131 ? 125.905 100.872 86.680  1.00 7.17   ? 126 LEU B CA    1 
ATOM   4851 C C     . LEU C 3 131 ? 125.999 99.361  86.500  1.00 7.17   ? 126 LEU B C     1 
ATOM   4852 O O     . LEU C 3 131 ? 126.093 98.627  87.490  1.00 7.17   ? 126 LEU B O     1 
ATOM   4853 C CB    . LEU C 3 131 ? 124.439 101.302 86.582  1.00 7.17   ? 126 LEU B CB    1 
ATOM   4854 C CG    . LEU C 3 131 ? 124.126 102.768 86.884  1.00 7.17   ? 126 LEU B CG    1 
ATOM   4855 C CD1   . LEU C 3 131 ? 122.636 103.019 86.744  1.00 7.17   ? 126 LEU B CD1   1 
ATOM   4856 C CD2   . LEU C 3 131 ? 124.609 103.163 88.268  1.00 7.17   ? 126 LEU B CD2   1 
ATOM   4857 N N     . LYS C 3 132 ? 125.976 98.880  85.256  1.00 7.57   ? 127 LYS B N     1 
ATOM   4858 C CA    . LYS C 3 132 ? 125.919 97.445  84.974  1.00 7.57   ? 127 LYS B CA    1 
ATOM   4859 C C     . LYS C 3 132 ? 127.333 96.930  84.721  1.00 7.57   ? 127 LYS B C     1 
ATOM   4860 O O     . LYS C 3 132 ? 127.767 96.730  83.585  1.00 7.57   ? 127 LYS B O     1 
ATOM   4861 C CB    . LYS C 3 132 ? 125.004 97.166  83.788  1.00 7.57   ? 127 LYS B CB    1 
ATOM   4862 C CG    . LYS C 3 132 ? 123.712 97.971  83.770  1.00 7.57   ? 127 LYS B CG    1 
ATOM   4863 C CD    . LYS C 3 132 ? 122.684 97.397  84.728  1.00 7.57   ? 127 LYS B CD    1 
ATOM   4864 C CE    . LYS C 3 132 ? 121.318 98.039  84.543  1.00 7.57   ? 127 LYS B CE    1 
ATOM   4865 N NZ    . LYS C 3 132 ? 120.856 98.040  83.126  1.00 7.57   ? 127 LYS B NZ    1 
ATOM   4866 N N     . THR C 3 133 ? 128.057 96.704  85.811  1.00 10.63  ? 128 THR B N     1 
ATOM   4867 C CA    . THR C 3 133 ? 129.395 96.137  85.765  1.00 10.63  ? 128 THR B CA    1 
ATOM   4868 C C     . THR C 3 133 ? 129.356 94.673  86.183  1.00 10.63  ? 128 THR B C     1 
ATOM   4869 O O     . THR C 3 133 ? 128.401 94.206  86.808  1.00 10.63  ? 128 THR B O     1 
ATOM   4870 C CB    . THR C 3 133 ? 130.359 96.907  86.677  1.00 10.63  ? 128 THR B CB    1 
ATOM   4871 O OG1   . THR C 3 133 ? 129.931 96.792  88.039  1.00 10.63  ? 128 THR B OG1   1 
ATOM   4872 C CG2   . THR C 3 133 ? 130.414 98.376  86.288  1.00 10.63  ? 128 THR B CG2   1 
ATOM   4873 N N     . ARG C 3 134 ? 130.415 93.949  85.824  1.00 14.14  ? 129 ARG B N     1 
ATOM   4874 C CA    . ARG C 3 134 ? 130.554 92.554  86.219  1.00 14.14  ? 129 ARG B CA    1 
ATOM   4875 C C     . ARG C 3 134 ? 131.085 92.397  87.637  1.00 14.14  ? 129 ARG B C     1 
ATOM   4876 O O     . ARG C 3 134 ? 131.076 91.281  88.164  1.00 14.14  ? 129 ARG B O     1 
ATOM   4877 C CB    . ARG C 3 134 ? 131.483 91.827  85.242  1.00 14.14  ? 129 ARG B CB    1 
ATOM   4878 C CG    . ARG C 3 134 ? 131.408 90.309  85.311  1.00 14.14  ? 129 ARG B CG    1 
ATOM   4879 C CD    . ARG C 3 134 ? 130.400 89.756  84.319  1.00 14.14  ? 129 ARG B CD    1 
ATOM   4880 N NE    . ARG C 3 134 ? 130.872 89.863  82.944  1.00 14.14  ? 129 ARG B NE    1 
ATOM   4881 C CZ    . ARG C 3 134 ? 131.589 88.940  82.317  1.00 14.14  ? 129 ARG B CZ    1 
ATOM   4882 N NH1   . ARG C 3 134 ? 131.952 87.817  82.917  1.00 14.14  ? 129 ARG B NH1   1 
ATOM   4883 N NH2   . ARG C 3 134 ? 131.953 89.148  81.055  1.00 14.14  ? 129 ARG B NH2   1 
ATOM   4884 N N     . GLU C 3 135 ? 131.539 93.479  88.264  1.00 12.40  ? 130 GLU B N     1 
ATOM   4885 C CA    . GLU C 3 135 ? 132.113 93.428  89.600  1.00 12.40  ? 130 GLU B CA    1 
ATOM   4886 C C     . GLU C 3 135 ? 131.092 93.699  90.698  1.00 12.40  ? 130 GLU B C     1 
ATOM   4887 O O     . GLU C 3 135 ? 131.445 93.632  91.879  1.00 12.40  ? 130 GLU B O     1 
ATOM   4888 C CB    . GLU C 3 135 ? 133.261 94.434  89.710  1.00 12.40  ? 130 GLU B CB    1 
ATOM   4889 C CG    . GLU C 3 135 ? 134.581 93.922  89.164  1.00 12.40  ? 130 GLU B CG    1 
ATOM   4890 C CD    . GLU C 3 135 ? 134.610 93.880  87.649  1.00 12.40  ? 130 GLU B CD    1 
ATOM   4891 O OE1   . GLU C 3 135 ? 135.342 93.036  87.090  1.00 12.40  ? 130 GLU B OE1   1 
ATOM   4892 O OE2   . GLU C 3 135 ? 133.901 94.689  87.015  1.00 12.40  ? 130 GLU B OE2   1 
ATOM   4893 N N     . GLY C 3 136 ? 129.846 94.006  90.344  1.00 10.69  ? 131 GLY B N     1 
ATOM   4894 C CA    . GLY C 3 136 ? 128.813 94.196  91.341  1.00 10.69  ? 131 GLY B CA    1 
ATOM   4895 C C     . GLY C 3 136 ? 128.769 95.563  91.983  1.00 10.69  ? 131 GLY B C     1 
ATOM   4896 O O     . GLY C 3 136 ? 128.013 95.755  92.939  1.00 10.69  ? 131 GLY B O     1 
ATOM   4897 N N     . ASN C 3 137 ? 129.550 96.518  91.495  1.00 10.82  ? 132 ASN B N     1 
ATOM   4898 C CA    . ASN C 3 137 ? 129.578 97.874  92.024  1.00 10.82  ? 132 ASN B CA    1 
ATOM   4899 C C     . ASN C 3 137 ? 129.330 98.869  90.893  1.00 10.82  ? 132 ASN B C     1 
ATOM   4900 O O     . ASN C 3 137 ? 129.066 98.492  89.749  1.00 10.82  ? 132 ASN B O     1 
ATOM   4901 C CB    . ASN C 3 137 ? 130.913 98.153  92.722  1.00 10.82  ? 132 ASN B CB    1 
ATOM   4902 C CG    . ASN C 3 137 ? 132.107 97.839  91.844  1.00 10.82  ? 132 ASN B CG    1 
ATOM   4903 O OD1   . ASN C 3 137 ? 132.011 97.849  90.618  1.00 10.82  ? 132 ASN B OD1   1 
ATOM   4904 N ND2   . ASN C 3 137 ? 133.242 97.555  92.471  1.00 10.82  ? 132 ASN B ND2   1 
ATOM   4905 N N     . VAL C 3 138 ? 129.412 100.153 91.228  1.00 8.50   ? 133 VAL B N     1 
ATOM   4906 C CA    . VAL C 3 138 ? 129.286 101.242 90.266  1.00 8.50   ? 133 VAL B CA    1 
ATOM   4907 C C     . VAL C 3 138 ? 130.609 101.994 90.239  1.00 8.50   ? 133 VAL B C     1 
ATOM   4908 O O     . VAL C 3 138 ? 131.138 102.369 91.292  1.00 8.50   ? 133 VAL B O     1 
ATOM   4909 C CB    . VAL C 3 138 ? 128.121 102.181 90.624  1.00 8.50   ? 133 VAL B CB    1 
ATOM   4910 C CG1   . VAL C 3 138 ? 128.055 103.352 89.653  1.00 8.50   ? 133 VAL B CG1   1 
ATOM   4911 C CG2   . VAL C 3 138 ? 126.810 101.416 90.632  1.00 8.50   ? 133 VAL B CG2   1 
ATOM   4912 N N     . ARG C 3 139 ? 131.141 102.211 89.039  1.00 11.17  ? 134 ARG B N     1 
ATOM   4913 C CA    . ARG C 3 139 ? 132.443 102.831 88.854  1.00 11.17  ? 134 ARG B CA    1 
ATOM   4914 C C     . ARG C 3 139 ? 132.326 104.036 87.930  1.00 11.17  ? 134 ARG B C     1 
ATOM   4915 O O     . ARG C 3 139 ? 131.353 104.186 87.186  1.00 11.17  ? 134 ARG B O     1 
ATOM   4916 C CB    . ARG C 3 139 ? 133.454 101.827 88.282  1.00 11.17  ? 134 ARG B CB    1 
ATOM   4917 C CG    . ARG C 3 139 ? 133.083 101.280 86.910  1.00 11.17  ? 134 ARG B CG    1 
ATOM   4918 C CD    . ARG C 3 139 ? 134.315 100.918 86.100  1.00 11.17  ? 134 ARG B CD    1 
ATOM   4919 N NE    . ARG C 3 139 ? 135.080 99.845  86.727  1.00 11.17  ? 134 ARG B NE    1 
ATOM   4920 C CZ    . ARG C 3 139 ? 135.023 98.567  86.374  1.00 11.17  ? 134 ARG B CZ    1 
ATOM   4921 N NH1   . ARG C 3 139 ? 134.234 98.150  85.396  1.00 11.17  ? 134 ARG B NH1   1 
ATOM   4922 N NH2   . ARG C 3 139 ? 135.776 97.683  87.022  1.00 11.17  ? 134 ARG B NH2   1 
ATOM   4923 N N     . VAL C 3 140 ? 133.340 104.894 87.984  1.00 10.61  ? 135 VAL B N     1 
ATOM   4924 C CA    . VAL C 3 140 ? 133.416 106.075 87.132  1.00 10.61  ? 135 VAL B CA    1 
ATOM   4925 C C     . VAL C 3 140 ? 133.820 105.612 85.738  1.00 10.61  ? 135 VAL B C     1 
ATOM   4926 O O     . VAL C 3 140 ? 134.972 105.235 85.509  1.00 10.61  ? 135 VAL B O     1 
ATOM   4927 C CB    . VAL C 3 140 ? 134.413 107.104 87.680  1.00 10.61  ? 135 VAL B CB    1 
ATOM   4928 C CG1   . VAL C 3 140 ? 134.565 108.265 86.712  1.00 10.61  ? 135 VAL B CG1   1 
ATOM   4929 C CG2   . VAL C 3 140 ? 133.976 107.609 89.040  1.00 10.61  ? 135 VAL B CG2   1 
ATOM   4930 N N     . SER C 3 141 ? 132.872 105.637 84.801  1.00 10.25  ? 136 SER B N     1 
ATOM   4931 C CA    . SER C 3 141 ? 133.192 105.252 83.432  1.00 10.25  ? 136 SER B CA    1 
ATOM   4932 C C     . SER C 3 141 ? 134.092 106.288 82.772  1.00 10.25  ? 136 SER B C     1 
ATOM   4933 O O     . SER C 3 141 ? 135.121 105.941 82.182  1.00 10.25  ? 136 SER B O     1 
ATOM   4934 C CB    . SER C 3 141 ? 131.908 105.065 82.625  1.00 10.25  ? 136 SER B CB    1 
ATOM   4935 O OG    . SER C 3 141 ? 131.355 106.314 82.257  1.00 10.25  ? 136 SER B OG    1 
ATOM   4936 N N     . ARG C 3 142 ? 133.728 107.566 82.872  1.00 13.70  ? 137 ARG B N     1 
ATOM   4937 C CA    . ARG C 3 142 ? 134.496 108.623 82.223  1.00 13.70  ? 137 ARG B CA    1 
ATOM   4938 C C     . ARG C 3 142 ? 134.299 109.943 82.955  1.00 13.70  ? 137 ARG B C     1 
ATOM   4939 O O     . ARG C 3 142 ? 133.390 110.077 83.775  1.00 13.70  ? 137 ARG B O     1 
ATOM   4940 C CB    . ARG C 3 142 ? 134.097 108.800 80.750  1.00 13.70  ? 137 ARG B CB    1 
ATOM   4941 C CG    . ARG C 3 142 ? 134.456 107.643 79.827  1.00 13.70  ? 137 ARG B CG    1 
ATOM   4942 C CD    . ARG C 3 142 ? 135.959 107.384 79.780  1.00 13.70  ? 137 ARG B CD    1 
ATOM   4943 N NE    . ARG C 3 142 ? 136.712 108.525 79.270  1.00 13.70  ? 137 ARG B NE    1 
ATOM   4944 C CZ    . ARG C 3 142 ? 137.058 108.698 78.002  1.00 13.70  ? 137 ARG B CZ    1 
ATOM   4945 N NH1   . ARG C 3 142 ? 136.705 107.837 77.062  1.00 13.70  ? 137 ARG B NH1   1 
ATOM   4946 N NH2   . ARG C 3 142 ? 137.784 109.761 77.669  1.00 13.70  ? 137 ARG B NH2   1 
ATOM   4947 N N     . GLU C 3 143 ? 135.166 110.906 82.654  1.00 12.23  ? 138 GLU B N     1 
ATOM   4948 C CA    . GLU C 3 143 ? 135.018 112.285 83.102  1.00 12.23  ? 138 GLU B CA    1 
ATOM   4949 C C     . GLU C 3 143 ? 135.216 113.207 81.906  1.00 12.23  ? 138 GLU B C     1 
ATOM   4950 O O     . GLU C 3 143 ? 136.272 113.180 81.266  1.00 12.23  ? 138 GLU B O     1 
ATOM   4951 C CB    . GLU C 3 143 ? 136.017 112.614 84.210  1.00 12.23  ? 138 GLU B CB    1 
ATOM   4952 C CG    . GLU C 3 143 ? 135.722 111.921 85.525  1.00 12.23  ? 138 GLU B CG    1 
ATOM   4953 C CD    . GLU C 3 143 ? 136.912 111.912 86.459  1.00 12.23  ? 138 GLU B CD    1 
ATOM   4954 O OE1   . GLU C 3 143 ? 137.849 112.706 86.236  1.00 12.23  ? 138 GLU B OE1   1 
ATOM   4955 O OE2   . GLU C 3 143 ? 136.911 111.111 87.416  1.00 12.23  ? 138 GLU B OE2   1 
ATOM   4956 N N     . LEU C 3 144 ? 134.202 114.016 81.608  1.00 12.19  ? 139 LEU B N     1 
ATOM   4957 C CA    . LEU C 3 144 ? 134.247 114.958 80.498  1.00 12.19  ? 139 LEU B CA    1 
ATOM   4958 C C     . LEU C 3 144 ? 134.640 116.330 81.031  1.00 12.19  ? 139 LEU B C     1 
ATOM   4959 O O     . LEU C 3 144 ? 133.956 116.881 81.902  1.00 12.19  ? 139 LEU B O     1 
ATOM   4960 C CB    . LEU C 3 144 ? 132.891 115.022 79.798  1.00 12.19  ? 139 LEU B CB    1 
ATOM   4961 C CG    . LEU C 3 144 ? 132.364 113.696 79.247  1.00 12.19  ? 139 LEU B CG    1 
ATOM   4962 C CD1   . LEU C 3 144 ? 130.873 113.784 79.001  1.00 12.19  ? 139 LEU B CD1   1 
ATOM   4963 C CD2   . LEU C 3 144 ? 133.092 113.309 77.972  1.00 12.19  ? 139 LEU B CD2   1 
ATOM   4964 N N     . ALA C 3 145 ? 135.735 116.876 80.508  1.00 13.26  ? 140 ALA B N     1 
ATOM   4965 C CA    . ALA C 3 145 ? 136.281 118.149 80.948  1.00 13.26  ? 140 ALA B CA    1 
ATOM   4966 C C     . ALA C 3 145 ? 136.503 119.062 79.750  1.00 13.26  ? 140 ALA B C     1 
ATOM   4967 O O     . ALA C 3 145 ? 136.657 118.600 78.616  1.00 13.26  ? 140 ALA B O     1 
ATOM   4968 C CB    . ALA C 3 145 ? 137.602 117.956 81.701  1.00 13.26  ? 140 ALA B CB    1 
ATOM   4969 N N     . GLY C 3 146 ? 136.529 120.365 80.015  1.00 13.54  ? 141 GLY B N     1 
ATOM   4970 C CA    . GLY C 3 146 ? 136.696 121.352 78.967  1.00 13.54  ? 141 GLY B CA    1 
ATOM   4971 C C     . GLY C 3 146 ? 135.857 122.592 79.190  1.00 13.54  ? 141 GLY B C     1 
ATOM   4972 O O     . GLY C 3 146 ? 136.190 123.671 78.691  1.00 13.54  ? 141 GLY B O     1 
ATOM   4973 N N     . HIS C 3 147 ? 134.760 122.452 79.931  1.00 14.93  ? 142 HIS B N     1 
ATOM   4974 C CA    . HIS C 3 147 ? 133.967 123.611 80.316  1.00 14.93  ? 142 HIS B CA    1 
ATOM   4975 C C     . HIS C 3 147 ? 134.740 124.465 81.310  1.00 14.93  ? 142 HIS B C     1 
ATOM   4976 O O     . HIS C 3 147 ? 135.485 123.950 82.148  1.00 14.93  ? 142 HIS B O     1 
ATOM   4977 C CB    . HIS C 3 147 ? 132.638 123.167 80.930  1.00 14.93  ? 142 HIS B CB    1 
ATOM   4978 C CG    . HIS C 3 147 ? 131.562 122.909 79.922  1.00 14.93  ? 142 HIS B CG    1 
ATOM   4979 N ND1   . HIS C 3 147 ? 131.238 123.809 78.931  1.00 14.93  ? 142 HIS B ND1   1 
ATOM   4980 C CD2   . HIS C 3 147 ? 130.725 121.857 79.762  1.00 14.93  ? 142 HIS B CD2   1 
ATOM   4981 C CE1   . HIS C 3 147 ? 130.254 123.320 78.199  1.00 14.93  ? 142 HIS B CE1   1 
ATOM   4982 N NE2   . HIS C 3 147 ? 129.924 122.137 78.682  1.00 14.93  ? 142 HIS B NE2   1 
ATOM   4983 N N     . THR C 3 148 ? 134.561 125.782 81.214  1.00 18.48  ? 143 THR B N     1 
ATOM   4984 C CA    . THR C 3 148 ? 135.220 126.709 82.123  1.00 18.48  ? 143 THR B CA    1 
ATOM   4985 C C     . THR C 3 148 ? 134.325 127.158 83.269  1.00 18.48  ? 143 THR B C     1 
ATOM   4986 O O     . THR C 3 148 ? 134.829 127.378 84.376  1.00 18.48  ? 143 THR B O     1 
ATOM   4987 C CB    . THR C 3 148 ? 135.709 127.947 81.362  1.00 18.48  ? 143 THR B CB    1 
ATOM   4988 O OG1   . THR C 3 148 ? 136.662 127.554 80.367  1.00 18.48  ? 143 THR B OG1   1 
ATOM   4989 C CG2   . THR C 3 148 ? 136.359 128.941 82.311  1.00 18.48  ? 143 THR B CG2   1 
ATOM   4990 N N     . GLY C 3 149 ? 133.019 127.294 83.036  1.00 16.99  ? 144 GLY B N     1 
ATOM   4991 C CA    . GLY C 3 149 ? 132.085 127.653 84.077  1.00 16.99  ? 144 GLY B CA    1 
ATOM   4992 C C     . GLY C 3 149 ? 131.452 126.423 84.707  1.00 16.99  ? 144 GLY B C     1 
ATOM   4993 O O     . GLY C 3 149 ? 131.568 125.306 84.211  1.00 16.99  ? 144 GLY B O     1 
ATOM   4994 N N     . TYR C 3 150 ? 130.768 126.652 85.826  1.00 16.56  ? 145 TYR B N     1 
ATOM   4995 C CA    . TYR C 3 150 ? 130.165 125.551 86.561  1.00 16.56  ? 145 TYR B CA    1 
ATOM   4996 C C     . TYR C 3 150 ? 129.224 124.757 85.660  1.00 16.56  ? 145 TYR B C     1 
ATOM   4997 O O     . TYR C 3 150 ? 128.773 125.227 84.612  1.00 16.56  ? 145 TYR B O     1 
ATOM   4998 C CB    . TYR C 3 150 ? 129.419 126.069 87.791  1.00 16.56  ? 145 TYR B CB    1 
ATOM   4999 C CG    . TYR C 3 150 ? 128.184 126.877 87.475  1.00 16.56  ? 145 TYR B CG    1 
ATOM   5000 C CD1   . TYR C 3 150 ? 126.951 126.264 87.308  1.00 16.56  ? 145 TYR B CD1   1 
ATOM   5001 C CD2   . TYR C 3 150 ? 128.252 128.255 87.344  1.00 16.56  ? 145 TYR B CD2   1 
ATOM   5002 C CE1   . TYR C 3 150 ? 125.824 127.001 87.015  1.00 16.56  ? 145 TYR B CE1   1 
ATOM   5003 C CE2   . TYR C 3 150 ? 127.131 128.998 87.053  1.00 16.56  ? 145 TYR B CE2   1 
ATOM   5004 C CZ    . TYR C 3 150 ? 125.920 128.368 86.890  1.00 16.56  ? 145 TYR B CZ    1 
ATOM   5005 O OH    . TYR C 3 150 ? 124.802 129.111 86.602  1.00 16.56  ? 145 TYR B OH    1 
ATOM   5006 N N     . LEU C 3 151 ? 128.933 123.532 86.084  1.00 13.56  ? 146 LEU B N     1 
ATOM   5007 C CA    . LEU C 3 151 ? 128.139 122.592 85.305  1.00 13.56  ? 146 LEU B CA    1 
ATOM   5008 C C     . LEU C 3 151 ? 126.676 122.725 85.706  1.00 13.56  ? 146 LEU B C     1 
ATOM   5009 O O     . LEU C 3 151 ? 126.290 122.313 86.804  1.00 13.56  ? 146 LEU B O     1 
ATOM   5010 C CB    . LEU C 3 151 ? 128.628 121.163 85.532  1.00 13.56  ? 146 LEU B CB    1 
ATOM   5011 C CG    . LEU C 3 151 ? 127.932 120.096 84.691  1.00 13.56  ? 146 LEU B CG    1 
ATOM   5012 C CD1   . LEU C 3 151 ? 128.252 120.323 83.245  1.00 13.56  ? 146 LEU B CD1   1 
ATOM   5013 C CD2   . LEU C 3 151 ? 128.339 118.704 85.111  1.00 13.56  ? 146 LEU B CD2   1 
ATOM   5014 N N     . SER C 3 152 ? 125.866 123.287 84.814  1.00 14.36  ? 147 SER B N     1 
ATOM   5015 C CA    . SER C 3 152 ? 124.461 123.553 85.098  1.00 14.36  ? 147 SER B CA    1 
ATOM   5016 C C     . SER C 3 152 ? 123.556 122.360 84.825  1.00 14.36  ? 147 SER B C     1 
ATOM   5017 O O     . SER C 3 152 ? 122.708 122.033 85.659  1.00 14.36  ? 147 SER B O     1 
ATOM   5018 C CB    . SER C 3 152 ? 123.978 124.750 84.276  1.00 14.36  ? 147 SER B CB    1 
ATOM   5019 O OG    . SER C 3 152 ? 124.871 125.842 84.393  1.00 14.36  ? 147 SER B OG    1 
ATOM   5020 N N     . CYS C 3 153 ? 123.707 121.701 83.678  1.00 12.79  ? 148 CYS B N     1 
ATOM   5021 C CA    . CYS C 3 153 ? 122.839 120.587 83.330  1.00 12.79  ? 148 CYS B CA    1 
ATOM   5022 C C     . CYS C 3 153 ? 123.547 119.684 82.330  1.00 12.79  ? 148 CYS B C     1 
ATOM   5023 O O     . CYS C 3 153 ? 124.476 120.100 81.633  1.00 12.79  ? 148 CYS B O     1 
ATOM   5024 C CB    . CYS C 3 153 ? 121.505 121.079 82.759  1.00 12.79  ? 148 CYS B CB    1 
ATOM   5025 S SG    . CYS C 3 153 ? 120.160 119.878 82.857  1.00 12.79  ? 148 CYS B SG    1 
ATOM   5026 N N     . CYS C 3 154 ? 123.083 118.437 82.264  1.00 10.91  ? 149 CYS B N     1 
ATOM   5027 C CA    . CYS C 3 154 ? 123.647 117.443 81.363  1.00 10.91  ? 149 CYS B CA    1 
ATOM   5028 C C     . CYS C 3 154 ? 122.591 116.383 81.091  1.00 10.91  ? 149 CYS B C     1 
ATOM   5029 O O     . CYS C 3 154 ? 121.849 116.000 81.997  1.00 10.91  ? 149 CYS B O     1 
ATOM   5030 C CB    . CYS C 3 154 ? 124.908 116.803 81.955  1.00 10.91  ? 149 CYS B CB    1 
ATOM   5031 S SG    . CYS C 3 154 ? 124.604 115.755 83.394  1.00 10.91  ? 149 CYS B SG    1 
ATOM   5032 N N     . ARG C 3 155 ? 122.527 115.922 79.843  1.00 10.45  ? 150 ARG B N     1 
ATOM   5033 C CA    . ARG C 3 155 ? 121.540 114.927 79.440  1.00 10.45  ? 150 ARG B CA    1 
ATOM   5034 C C     . ARG C 3 155 ? 122.150 113.972 78.426  1.00 10.45  ? 150 ARG B C     1 
ATOM   5035 O O     . ARG C 3 155 ? 122.773 114.407 77.452  1.00 10.45  ? 150 ARG B O     1 
ATOM   5036 C CB    . ARG C 3 155 ? 120.293 115.594 78.850  1.00 10.45  ? 150 ARG B CB    1 
ATOM   5037 C CG    . ARG C 3 155 ? 119.450 116.343 79.865  1.00 10.45  ? 150 ARG B CG    1 
ATOM   5038 C CD    . ARG C 3 155 ? 118.897 115.403 80.918  1.00 10.45  ? 150 ARG B CD    1 
ATOM   5039 N NE    . ARG C 3 155 ? 117.758 115.979 81.625  1.00 10.45  ? 150 ARG B NE    1 
ATOM   5040 C CZ    . ARG C 3 155 ? 117.712 116.225 82.928  1.00 10.45  ? 150 ARG B CZ    1 
ATOM   5041 N NH1   . ARG C 3 155 ? 118.739 115.971 83.724  1.00 10.45  ? 150 ARG B NH1   1 
ATOM   5042 N NH2   . ARG C 3 155 ? 116.601 116.740 83.449  1.00 10.45  ? 150 ARG B NH2   1 
ATOM   5043 N N     . PHE C 3 156 ? 121.962 112.675 78.659  1.00 9.58   ? 151 PHE B N     1 
ATOM   5044 C CA    . PHE C 3 156 ? 122.436 111.660 77.729  1.00 9.58   ? 151 PHE B CA    1 
ATOM   5045 C C     . PHE C 3 156 ? 121.635 111.707 76.436  1.00 9.58   ? 151 PHE B C     1 
ATOM   5046 O O     . PHE C 3 156 ? 120.402 111.749 76.458  1.00 9.58   ? 151 PHE B O     1 
ATOM   5047 C CB    . PHE C 3 156 ? 122.311 110.271 78.349  1.00 9.58   ? 151 PHE B CB    1 
ATOM   5048 C CG    . PHE C 3 156 ? 123.421 109.915 79.290  1.00 9.58   ? 151 PHE B CG    1 
ATOM   5049 C CD1   . PHE C 3 156 ? 124.626 109.440 78.810  1.00 9.58   ? 151 PHE B CD1   1 
ATOM   5050 C CD2   . PHE C 3 156 ? 123.248 110.032 80.655  1.00 9.58   ? 151 PHE B CD2   1 
ATOM   5051 C CE1   . PHE C 3 156 ? 125.644 109.103 79.676  1.00 9.58   ? 151 PHE B CE1   1 
ATOM   5052 C CE2   . PHE C 3 156 ? 124.261 109.696 81.524  1.00 9.58   ? 151 PHE B CE2   1 
ATOM   5053 C CZ    . PHE C 3 156 ? 125.460 109.231 81.035  1.00 9.58   ? 151 PHE B CZ    1 
ATOM   5054 N N     . LEU C 3 157 ? 122.339 111.697 75.305  1.00 15.07  ? 152 LEU B N     1 
ATOM   5055 C CA    . LEU C 3 157 ? 121.699 111.447 74.020  1.00 15.07  ? 152 LEU B CA    1 
ATOM   5056 C C     . LEU C 3 157 ? 121.648 109.957 73.714  1.00 15.07  ? 152 LEU B C     1 
ATOM   5057 O O     . LEU C 3 157 ? 120.656 109.466 73.164  1.00 15.07  ? 152 LEU B O     1 
ATOM   5058 C CB    . LEU C 3 157 ? 122.443 112.183 72.903  1.00 15.07  ? 152 LEU B CB    1 
ATOM   5059 C CG    . LEU C 3 157 ? 122.245 113.697 72.851  1.00 15.07  ? 152 LEU B CG    1 
ATOM   5060 C CD1   . LEU C 3 157 ? 123.489 114.370 72.314  1.00 15.07  ? 152 LEU B CD1   1 
ATOM   5061 C CD2   . LEU C 3 157 ? 121.041 114.057 72.001  1.00 15.07  ? 152 LEU B CD2   1 
ATOM   5062 N N     . ASP C 3 158 ? 122.703 109.235 74.070  1.00 14.88  ? 153 ASP B N     1 
ATOM   5063 C CA    . ASP C 3 158 ? 122.778 107.792 73.902  1.00 14.88  ? 153 ASP B CA    1 
ATOM   5064 C C     . ASP C 3 158 ? 123.747 107.261 74.953  1.00 14.88  ? 153 ASP B C     1 
ATOM   5065 O O     . ASP C 3 158 ? 124.160 107.993 75.859  1.00 14.88  ? 153 ASP B O     1 
ATOM   5066 C CB    . ASP C 3 158 ? 123.192 107.442 72.462  1.00 14.88  ? 153 ASP B CB    1 
ATOM   5067 C CG    . ASP C 3 158 ? 122.005 107.305 71.533  1.00 14.88  ? 153 ASP B CG    1 
ATOM   5068 O OD1   . ASP C 3 158 ? 121.070 106.550 71.872  1.00 14.88  ? 153 ASP B OD1   1 
ATOM   5069 O OD2   . ASP C 3 158 ? 122.009 107.951 70.464  1.00 14.88  ? 153 ASP B OD2   1 
ATOM   5070 N N     . ASP C 3 159 ? 124.117 105.992 74.838  1.00 13.26  ? 154 ASP B N     1 
ATOM   5071 C CA    . ASP C 3 159 ? 125.077 105.385 75.747  1.00 13.26  ? 154 ASP B CA    1 
ATOM   5072 C C     . ASP C 3 159 ? 126.494 105.903 75.542  1.00 13.26  ? 154 ASP B C     1 
ATOM   5073 O O     . ASP C 3 159 ? 127.367 105.617 76.367  1.00 13.26  ? 154 ASP B O     1 
ATOM   5074 C CB    . ASP C 3 159 ? 125.051 103.860 75.589  1.00 13.26  ? 154 ASP B CB    1 
ATOM   5075 C CG    . ASP C 3 159 ? 125.466 103.408 74.201  1.00 13.26  ? 154 ASP B CG    1 
ATOM   5076 O OD1   . ASP C 3 159 ? 125.738 104.273 73.342  1.00 13.26  ? 154 ASP B OD1   1 
ATOM   5077 O OD2   . ASP C 3 159 ? 125.518 102.182 73.967  1.00 13.26  ? 154 ASP B OD2   1 
ATOM   5078 N N     . ASN C 3 160 ? 126.742 106.660 74.469  1.00 14.81  ? 155 ASN B N     1 
ATOM   5079 C CA    . ASN C 3 160 ? 128.077 107.158 74.163  1.00 14.81  ? 155 ASN B CA    1 
ATOM   5080 C C     . ASN C 3 160 ? 128.079 108.620 73.732  1.00 14.81  ? 155 ASN B C     1 
ATOM   5081 O O     . ASN C 3 160 ? 129.102 109.099 73.229  1.00 14.81  ? 155 ASN B O     1 
ATOM   5082 C CB    . ASN C 3 160 ? 128.725 106.302 73.069  1.00 14.81  ? 155 ASN B CB    1 
ATOM   5083 C CG    . ASN C 3 160 ? 130.235 106.418 73.058  1.00 14.81  ? 155 ASN B CG    1 
ATOM   5084 O OD1   . ASN C 3 160 ? 130.888 106.253 74.087  1.00 14.81  ? 155 ASN B OD1   1 
ATOM   5085 N ND2   . ASN C 3 160 ? 130.797 106.705 71.891  1.00 14.81  ? 155 ASN B ND2   1 
ATOM   5086 N N     . GLN C 3 161 ? 126.976 109.343 73.912  1.00 14.02  ? 156 GLN B N     1 
ATOM   5087 C CA    . GLN C 3 161 ? 126.869 110.714 73.428  1.00 14.02  ? 156 GLN B CA    1 
ATOM   5088 C C     . GLN C 3 161 ? 125.992 111.504 74.389  1.00 14.02  ? 156 GLN B C     1 
ATOM   5089 O O     . GLN C 3 161 ? 124.832 111.145 74.610  1.00 14.02  ? 156 GLN B O     1 
ATOM   5090 C CB    . GLN C 3 161 ? 126.301 110.731 72.007  1.00 14.02  ? 156 GLN B CB    1 
ATOM   5091 C CG    . GLN C 3 161 ? 126.342 112.070 71.311  1.00 14.02  ? 156 GLN B CG    1 
ATOM   5092 C CD    . GLN C 3 161 ? 125.905 111.965 69.864  1.00 14.02  ? 156 GLN B CD    1 
ATOM   5093 O OE1   . GLN C 3 161 ? 125.552 110.886 69.391  1.00 14.02  ? 156 GLN B OE1   1 
ATOM   5094 N NE2   . GLN C 3 161 ? 125.936 113.082 69.150  1.00 14.02  ? 156 GLN B NE2   1 
ATOM   5095 N N     . ILE C 3 162 ? 126.552 112.568 74.965  1.00 11.86  ? 157 ILE B N     1 
ATOM   5096 C CA    . ILE C 3 162 ? 125.898 113.359 76.001  1.00 11.86  ? 157 ILE B CA    1 
ATOM   5097 C C     . ILE C 3 162 ? 126.014 114.834 75.637  1.00 11.86  ? 157 ILE B C     1 
ATOM   5098 O O     . ILE C 3 162 ? 126.932 115.241 74.918  1.00 11.86  ? 157 ILE B O     1 
ATOM   5099 C CB    . ILE C 3 162 ? 126.522 113.078 77.388  1.00 11.86  ? 157 ILE B CB    1 
ATOM   5100 C CG1   . ILE C 3 162 ? 125.745 113.788 78.495  1.00 11.86  ? 157 ILE B CG1   1 
ATOM   5101 C CG2   . ILE C 3 162 ? 127.979 113.502 77.421  1.00 11.86  ? 157 ILE B CG2   1 
ATOM   5102 C CD1   . ILE C 3 162 ? 125.888 113.139 79.850  1.00 11.86  ? 157 ILE B CD1   1 
ATOM   5103 N N     . VAL C 3 163 ? 125.076 115.638 76.137  1.00 13.37  ? 158 VAL B N     1 
ATOM   5104 C CA    . VAL C 3 163 ? 125.048 117.077 75.888  1.00 13.37  ? 158 VAL B CA    1 
ATOM   5105 C C     . VAL C 3 163 ? 125.058 117.795 77.230  1.00 13.37  ? 158 VAL B C     1 
ATOM   5106 O O     . VAL C 3 163 ? 124.415 117.348 78.186  1.00 13.37  ? 158 VAL B O     1 
ATOM   5107 C CB    . VAL C 3 163 ? 123.825 117.488 75.049  1.00 13.37  ? 158 VAL B CB    1 
ATOM   5108 C CG1   . VAL C 3 163 ? 122.532 117.089 75.740  1.00 13.37  ? 158 VAL B CG1   1 
ATOM   5109 C CG2   . VAL C 3 163 ? 123.850 118.984 74.777  1.00 13.37  ? 158 VAL B CG2   1 
ATOM   5110 N N     . THR C 3 164 ? 125.793 118.902 77.301  1.00 13.92  ? 159 THR B N     1 
ATOM   5111 C CA    . THR C 3 164 ? 126.049 119.602 78.551  1.00 13.92  ? 159 THR B CA    1 
ATOM   5112 C C     . THR C 3 164 ? 125.855 121.101 78.378  1.00 13.92  ? 159 THR B C     1 
ATOM   5113 O O     . THR C 3 164 ? 126.057 121.638 77.287  1.00 13.92  ? 159 THR B O     1 
ATOM   5114 C CB    . THR C 3 164 ? 127.475 119.326 79.033  1.00 13.92  ? 159 THR B CB    1 
ATOM   5115 O OG1   . THR C 3 164 ? 127.611 117.941 79.374  1.00 13.92  ? 159 THR B OG1   1 
ATOM   5116 C CG2   . THR C 3 164 ? 127.816 120.180 80.222  1.00 13.92  ? 159 THR B CG2   1 
ATOM   5117 N N     . SER C 3 165 ? 125.478 121.769 79.465  1.00 15.89  ? 160 SER B N     1 
ATOM   5118 C CA    . SER C 3 165 ? 125.451 123.222 79.556  1.00 15.89  ? 160 SER B CA    1 
ATOM   5119 C C     . SER C 3 165 ? 126.402 123.674 80.656  1.00 15.89  ? 160 SER B C     1 
ATOM   5120 O O     . SER C 3 165 ? 126.664 122.932 81.606  1.00 15.89  ? 160 SER B O     1 
ATOM   5121 C CB    . SER C 3 165 ? 124.040 123.729 79.857  1.00 15.89  ? 160 SER B CB    1 
ATOM   5122 O OG    . SER C 3 165 ? 124.063 125.097 80.209  1.00 15.89  ? 160 SER B OG    1 
ATOM   5123 N N     . SER C 3 166 ? 126.923 124.896 80.532  1.00 16.86  ? 161 SER B N     1 
ATOM   5124 C CA    . SER C 3 166 ? 127.840 125.416 81.538  1.00 16.86  ? 161 SER B CA    1 
ATOM   5125 C C     . SER C 3 166 ? 127.571 126.894 81.780  1.00 16.86  ? 161 SER B C     1 
ATOM   5126 O O     . SER C 3 166 ? 126.776 127.532 81.085  1.00 16.86  ? 161 SER B O     1 
ATOM   5127 C CB    . SER C 3 166 ? 129.299 125.207 81.123  1.00 16.86  ? 161 SER B CB    1 
ATOM   5128 O OG    . SER C 3 166 ? 130.182 125.643 82.141  1.00 16.86  ? 161 SER B OG    1 
ATOM   5129 N N     . GLY C 3 167 ? 128.249 127.433 82.791  1.00 18.79  ? 162 GLY B N     1 
ATOM   5130 C CA    . GLY C 3 167 ? 128.154 128.841 83.118  1.00 18.79  ? 162 GLY B CA    1 
ATOM   5131 C C     . GLY C 3 167 ? 129.138 129.684 82.333  1.00 18.79  ? 162 GLY B C     1 
ATOM   5132 O O     . GLY C 3 167 ? 129.297 130.878 82.602  1.00 18.79  ? 162 GLY B O     1 
ATOM   5133 N N     . ASP C 3 168 ? 129.804 129.071 81.356  1.00 20.05  ? 163 ASP B N     1 
ATOM   5134 C CA    . ASP C 3 168 ? 130.689 129.781 80.446  1.00 20.05  ? 163 ASP B CA    1 
ATOM   5135 C C     . ASP C 3 168 ? 129.918 130.398 79.285  1.00 20.05  ? 163 ASP B C     1 
ATOM   5136 O O     . ASP C 3 168 ? 130.534 130.879 78.330  1.00 20.05  ? 163 ASP B O     1 
ATOM   5137 C CB    . ASP C 3 168 ? 131.763 128.819 79.909  1.00 20.05  ? 163 ASP B CB    1 
ATOM   5138 C CG    . ASP C 3 168 ? 132.898 129.528 79.172  1.00 20.05  ? 163 ASP B CG    1 
ATOM   5139 O OD1   . ASP C 3 168 ? 132.755 130.701 78.775  1.00 20.05  ? 163 ASP B OD1   1 
ATOM   5140 O OD2   . ASP C 3 168 ? 133.946 128.884 78.958  1.00 20.05  ? 163 ASP B OD2   1 
ATOM   5141 N N     . THR C 3 169 ? 128.587 130.391 79.343  1.00 21.30  ? 164 THR B N     1 
ATOM   5142 C CA    . THR C 3 169 ? 127.763 130.882 78.247  1.00 21.30  ? 164 THR B CA    1 
ATOM   5143 C C     . THR C 3 169 ? 127.829 129.902 77.084  1.00 21.30  ? 164 THR B C     1 
ATOM   5144 O O     . THR C 3 169 ? 127.697 130.301 75.922  1.00 21.30  ? 164 THR B O     1 
ATOM   5145 C CB    . THR C 3 169 ? 128.219 132.270 77.787  1.00 21.30  ? 164 THR B CB    1 
ATOM   5146 O OG1   . THR C 3 169 ? 129.472 132.161 77.099  1.00 21.30  ? 164 THR B OG1   1 
ATOM   5147 C CG2   . THR C 3 169 ? 128.388 133.207 78.973  1.00 21.30  ? 164 THR B CG2   1 
ATOM   5148 N N     . THR C 3 170 ? 128.032 128.620 77.384  1.00 19.61  ? 165 THR B N     1 
ATOM   5149 C CA    . THR C 3 170 ? 128.294 127.638 76.344  1.00 19.61  ? 165 THR B CA    1 
ATOM   5150 C C     . THR C 3 170 ? 127.599 126.321 76.661  1.00 19.61  ? 165 THR B C     1 
ATOM   5151 O O     . THR C 3 170 ? 127.240 126.038 77.811  1.00 19.61  ? 165 THR B O     1 
ATOM   5152 C CB    . THR C 3 170 ? 129.800 127.389 76.174  1.00 19.61  ? 165 THR B CB    1 
ATOM   5153 O OG1   . THR C 3 170 ? 130.369 126.995 77.429  1.00 19.61  ? 165 THR B OG1   1 
ATOM   5154 C CG2   . THR C 3 170 ? 130.501 128.644 75.674  1.00 19.61  ? 165 THR B CG2   1 
ATOM   5155 N N     . CYS C 3 171 ? 127.397 125.535 75.609  1.00 18.41  ? 166 CYS B N     1 
ATOM   5156 C CA    . CYS C 3 171 ? 127.005 124.137 75.703  1.00 18.41  ? 166 CYS B CA    1 
ATOM   5157 C C     . CYS C 3 171 ? 127.992 123.290 74.909  1.00 18.41  ? 166 CYS B C     1 
ATOM   5158 O O     . CYS C 3 171 ? 128.716 123.784 74.044  1.00 18.41  ? 166 CYS B O     1 
ATOM   5159 C CB    . CYS C 3 171 ? 125.574 123.930 75.193  1.00 18.41  ? 166 CYS B CB    1 
ATOM   5160 S SG    . CYS C 3 171 ? 124.297 124.603 76.283  1.00 18.41  ? 166 CYS B SG    1 
ATOM   5161 N N     . ALA C 3 172 ? 128.018 121.998 75.214  1.00 16.35  ? 167 ALA B N     1 
ATOM   5162 C CA    . ALA C 3 172 ? 129.011 121.104 74.625  1.00 16.35  ? 167 ALA B CA    1 
ATOM   5163 C C     . ALA C 3 172 ? 128.377 119.759 74.315  1.00 16.35  ? 167 ALA B C     1 
ATOM   5164 O O     . ALA C 3 172 ? 127.725 119.164 75.177  1.00 16.35  ? 167 ALA B O     1 
ATOM   5165 C CB    . ALA C 3 172 ? 130.204 120.927 75.565  1.00 16.35  ? 167 ALA B CB    1 
ATOM   5166 N N     . LEU C 3 173 ? 128.572 119.287 73.087  1.00 16.79  ? 168 LEU B N     1 
ATOM   5167 C CA    . LEU C 3 173 ? 128.222 117.927 72.702  1.00 16.79  ? 168 LEU B CA    1 
ATOM   5168 C C     . LEU C 3 173 ? 129.491 117.085 72.715  1.00 16.79  ? 168 LEU B C     1 
ATOM   5169 O O     . LEU C 3 173 ? 130.442 117.377 71.981  1.00 16.79  ? 168 LEU B O     1 
ATOM   5170 C CB    . LEU C 3 173 ? 127.575 117.905 71.319  1.00 16.79  ? 168 LEU B CB    1 
ATOM   5171 C CG    . LEU C 3 173 ? 127.250 116.522 70.752  1.00 16.79  ? 168 LEU B CG    1 
ATOM   5172 C CD1   . LEU C 3 173 ? 126.051 115.936 71.468  1.00 16.79  ? 168 LEU B CD1   1 
ATOM   5173 C CD2   . LEU C 3 173 ? 127.006 116.608 69.256  1.00 16.79  ? 168 LEU B CD2   1 
ATOM   5174 N N     . TRP C 3 174 ? 129.499 116.041 73.537  1.00 13.80  ? 169 TRP B N     1 
ATOM   5175 C CA    . TRP C 3 174 ? 130.673 115.209 73.748  1.00 13.80  ? 169 TRP B CA    1 
ATOM   5176 C C     . TRP C 3 174 ? 130.496 113.843 73.099  1.00 13.80  ? 169 TRP B C     1 
ATOM   5177 O O     . TRP C 3 174 ? 129.397 113.437 72.715  1.00 13.80  ? 169 TRP B O     1 
ATOM   5178 C CB    . TRP C 3 174 ? 130.959 115.027 75.243  1.00 13.80  ? 169 TRP B CB    1 
ATOM   5179 C CG    . TRP C 3 174 ? 130.915 116.284 76.042  1.00 13.80  ? 169 TRP B CG    1 
ATOM   5180 C CD1   . TRP C 3 174 ? 129.806 116.984 76.408  1.00 13.80  ? 169 TRP B CD1   1 
ATOM   5181 C CD2   . TRP C 3 174 ? 132.034 116.989 76.587  1.00 13.80  ? 169 TRP B CD2   1 
ATOM   5182 N NE1   . TRP C 3 174 ? 130.165 118.085 77.145  1.00 13.80  ? 169 TRP B NE1   1 
ATOM   5183 C CE2   . TRP C 3 174 ? 131.528 118.110 77.269  1.00 13.80  ? 169 TRP B CE2   1 
ATOM   5184 C CE3   . TRP C 3 174 ? 133.415 116.780 76.564  1.00 13.80  ? 169 TRP B CE3   1 
ATOM   5185 C CZ2   . TRP C 3 174 ? 132.353 119.020 77.920  1.00 13.80  ? 169 TRP B CZ2   1 
ATOM   5186 C CZ3   . TRP C 3 174 ? 134.231 117.684 77.210  1.00 13.80  ? 169 TRP B CZ3   1 
ATOM   5187 C CH2   . TRP C 3 174 ? 133.699 118.791 77.879  1.00 13.80  ? 169 TRP B CH2   1 
ATOM   5188 N N     . ASP C 3 175 ? 131.619 113.138 72.987  1.00 16.10  ? 170 ASP B N     1 
ATOM   5189 C CA    . ASP C 3 175 ? 131.656 111.732 72.593  1.00 16.10  ? 170 ASP B CA    1 
ATOM   5190 C C     . ASP C 3 175 ? 132.296 110.991 73.762  1.00 16.10  ? 170 ASP B C     1 
ATOM   5191 O O     . ASP C 3 175 ? 133.502 111.111 73.995  1.00 16.10  ? 170 ASP B O     1 
ATOM   5192 C CB    . ASP C 3 175 ? 132.435 111.535 71.298  1.00 16.10  ? 170 ASP B CB    1 
ATOM   5193 C CG    . ASP C 3 175 ? 132.388 110.106 70.803  1.00 16.10  ? 170 ASP B CG    1 
ATOM   5194 O OD1   . ASP C 3 175 ? 131.339 109.696 70.266  1.00 16.10  ? 170 ASP B OD1   1 
ATOM   5195 O OD2   . ASP C 3 175 ? 133.401 109.391 70.953  1.00 16.10  ? 170 ASP B OD2   1 
ATOM   5196 N N     . ILE C 3 176 ? 131.485 110.228 74.497  1.00 13.09  ? 171 ILE B N     1 
ATOM   5197 C CA    . ILE C 3 176 ? 131.939 109.672 75.768  1.00 13.09  ? 171 ILE B CA    1 
ATOM   5198 C C     . ILE C 3 176 ? 133.111 108.724 75.562  1.00 13.09  ? 171 ILE B C     1 
ATOM   5199 O O     . ILE C 3 176 ? 134.016 108.654 76.402  1.00 13.09  ? 171 ILE B O     1 
ATOM   5200 C CB    . ILE C 3 176 ? 130.768 108.979 76.494  1.00 13.09  ? 171 ILE B CB    1 
ATOM   5201 C CG1   . ILE C 3 176 ? 129.601 109.955 76.679  1.00 13.09  ? 171 ILE B CG1   1 
ATOM   5202 C CG2   . ILE C 3 176 ? 131.226 108.446 77.843  1.00 13.09  ? 171 ILE B CG2   1 
ATOM   5203 C CD1   . ILE C 3 176 ? 128.316 109.308 77.136  1.00 13.09  ? 171 ILE B CD1   1 
ATOM   5204 N N     . GLU C 3 177 ? 133.120 107.980 74.456  1.00 17.16  ? 172 GLU B N     1 
ATOM   5205 C CA    . GLU C 3 177 ? 134.210 107.043 74.203  1.00 17.16  ? 172 GLU B CA    1 
ATOM   5206 C C     . GLU C 3 177 ? 135.542 107.775 74.071  1.00 17.16  ? 172 GLU B C     1 
ATOM   5207 O O     . GLU C 3 177 ? 136.528 107.421 74.727  1.00 17.16  ? 172 GLU B O     1 
ATOM   5208 C CB    . GLU C 3 177 ? 133.913 106.230 72.941  1.00 17.16  ? 172 GLU B CB    1 
ATOM   5209 C CG    . GLU C 3 177 ? 134.985 105.212 72.569  1.00 17.16  ? 172 GLU B CG    1 
ATOM   5210 C CD    . GLU C 3 177 ? 135.423 104.354 73.741  1.00 17.16  ? 172 GLU B CD    1 
ATOM   5211 O OE1   . GLU C 3 177 ? 135.048 103.164 73.779  1.00 17.16  ? 172 GLU B OE1   1 
ATOM   5212 O OE2   . GLU C 3 177 ? 136.144 104.867 74.623  1.00 17.16  ? 172 GLU B OE2   1 
ATOM   5213 N N     . THR C 3 178 ? 135.589 108.806 73.224  1.00 17.14  ? 173 THR B N     1 
ATOM   5214 C CA    . THR C 3 178 ? 136.840 109.529 73.012  1.00 17.14  ? 173 THR B CA    1 
ATOM   5215 C C     . THR C 3 178 ? 137.139 110.478 74.167  1.00 17.14  ? 173 THR B C     1 
ATOM   5216 O O     . THR C 3 178 ? 138.306 110.704 74.505  1.00 17.14  ? 173 THR B O     1 
ATOM   5217 C CB    . THR C 3 178 ? 136.784 110.300 71.694  1.00 17.14  ? 173 THR B CB    1 
ATOM   5218 O OG1   . THR C 3 178 ? 135.634 111.153 71.682  1.00 17.14  ? 173 THR B OG1   1 
ATOM   5219 C CG2   . THR C 3 178 ? 136.713 109.341 70.515  1.00 17.14  ? 173 THR B CG2   1 
ATOM   5220 N N     . GLY C 3 179 ? 136.103 111.043 74.781  1.00 16.22  ? 174 GLY B N     1 
ATOM   5221 C CA    . GLY C 3 179 ? 136.279 111.998 75.854  1.00 16.22  ? 174 GLY B CA    1 
ATOM   5222 C C     . GLY C 3 179 ? 136.491 113.427 75.414  1.00 16.22  ? 174 GLY B C     1 
ATOM   5223 O O     . GLY C 3 179 ? 136.740 114.288 76.266  1.00 16.22  ? 174 GLY B O     1 
ATOM   5224 N N     . GLN C 3 180 ? 136.403 113.708 74.119  1.00 18.06  ? 175 GLN B N     1 
ATOM   5225 C CA    . GLN C 3 180 ? 136.551 115.053 73.589  1.00 18.06  ? 175 GLN B CA    1 
ATOM   5226 C C     . GLN C 3 180 ? 135.183 115.623 73.240  1.00 18.06  ? 175 GLN B C     1 
ATOM   5227 O O     . GLN C 3 180 ? 134.256 114.889 72.889  1.00 18.06  ? 175 GLN B O     1 
ATOM   5228 C CB    . GLN C 3 180 ? 137.448 115.063 72.349  1.00 18.06  ? 175 GLN B CB    1 
ATOM   5229 C CG    . GLN C 3 180 ? 138.624 114.098 72.406  1.00 18.06  ? 175 GLN B CG    1 
ATOM   5230 C CD    . GLN C 3 180 ? 139.663 114.508 73.431  1.00 18.06  ? 175 GLN B CD    1 
ATOM   5231 O OE1   . GLN C 3 180 ? 140.151 115.637 73.419  1.00 18.06  ? 175 GLN B OE1   1 
ATOM   5232 N NE2   . GLN C 3 180 ? 140.010 113.588 74.325  1.00 18.06  ? 175 GLN B NE2   1 
ATOM   5233 N N     . GLN C 3 181 ? 135.063 116.944 73.344  1.00 17.14  ? 176 GLN B N     1 
ATOM   5234 C CA    . GLN C 3 181 ? 133.805 117.613 73.031  1.00 17.14  ? 176 GLN B CA    1 
ATOM   5235 C C     . GLN C 3 181 ? 133.659 117.722 71.518  1.00 17.14  ? 176 GLN B C     1 
ATOM   5236 O O     . GLN C 3 181 ? 134.412 118.444 70.859  1.00 17.14  ? 176 GLN B O     1 
ATOM   5237 C CB    . GLN C 3 181 ? 133.750 118.980 73.708  1.00 17.14  ? 176 GLN B CB    1 
ATOM   5238 C CG    . GLN C 3 181 ? 134.800 119.978 73.255  1.00 17.14  ? 176 GLN B CG    1 
ATOM   5239 C CD    . GLN C 3 181 ? 134.747 121.266 74.053  1.00 17.14  ? 176 GLN B CD    1 
ATOM   5240 O OE1   . GLN C 3 181 ? 133.898 121.432 74.927  1.00 17.14  ? 176 GLN B OE1   1 
ATOM   5241 N NE2   . GLN C 3 181 ? 135.657 122.185 73.754  1.00 17.14  ? 176 GLN B NE2   1 
ATOM   5242 N N     . THR C 3 182 ? 132.697 116.983 70.963  1.00 17.34  ? 177 THR B N     1 
ATOM   5243 C CA    . THR C 3 182 ? 132.523 116.955 69.515  1.00 17.34  ? 177 THR B CA    1 
ATOM   5244 C C     . THR C 3 182 ? 132.127 118.325 68.981  1.00 17.34  ? 177 THR B C     1 
ATOM   5245 O O     . THR C 3 182 ? 132.660 118.782 67.963  1.00 17.34  ? 177 THR B O     1 
ATOM   5246 C CB    . THR C 3 182 ? 131.475 115.909 69.136  1.00 17.34  ? 177 THR B CB    1 
ATOM   5247 O OG1   . THR C 3 182 ? 131.905 114.616 69.580  1.00 17.34  ? 177 THR B OG1   1 
ATOM   5248 C CG2   . THR C 3 182 ? 131.264 115.882 67.630  1.00 17.34  ? 177 THR B CG2   1 
ATOM   5249 N N     . THR C 3 183 ? 131.195 118.997 69.652  1.00 19.67  ? 178 THR B N     1 
ATOM   5250 C CA    . THR C 3 183 ? 130.715 120.300 69.218  1.00 19.67  ? 178 THR B CA    1 
ATOM   5251 C C     . THR C 3 183 ? 130.670 121.252 70.403  1.00 19.67  ? 178 THR B C     1 
ATOM   5252 O O     . THR C 3 183 ? 130.434 120.840 71.540  1.00 19.67  ? 178 THR B O     1 
ATOM   5253 C CB    . THR C 3 183 ? 129.319 120.204 68.583  1.00 19.67  ? 178 THR B CB    1 
ATOM   5254 O OG1   . THR C 3 183 ? 129.315 119.181 67.580  1.00 19.67  ? 178 THR B OG1   1 
ATOM   5255 C CG2   . THR C 3 183 ? 128.924 121.528 67.949  1.00 19.67  ? 178 THR B CG2   1 
ATOM   5256 N N     . THR C 3 184 ? 130.896 122.532 70.124  1.00 19.87  ? 179 THR B N     1 
ATOM   5257 C CA    . THR C 3 184 ? 130.763 123.591 71.114  1.00 19.87  ? 179 THR B CA    1 
ATOM   5258 C C     . THR C 3 184 ? 129.758 124.609 70.601  1.00 19.87  ? 179 THR B C     1 
ATOM   5259 O O     . THR C 3 184 ? 129.920 125.150 69.502  1.00 19.87  ? 179 THR B O     1 
ATOM   5260 C CB    . THR C 3 184 ? 132.110 124.264 71.397  1.00 19.87  ? 179 THR B CB    1 
ATOM   5261 O OG1   . THR C 3 184 ? 133.036 123.295 71.902  1.00 19.87  ? 179 THR B OG1   1 
ATOM   5262 C CG2   . THR C 3 184 ? 131.948 125.381 72.419  1.00 19.87  ? 179 THR B CG2   1 
ATOM   5263 N N     . PHE C 3 185 ? 128.723 124.865 71.394  1.00 22.00  ? 180 PHE B N     1 
ATOM   5264 C CA    . PHE C 3 185 ? 127.647 125.781 71.041  1.00 22.00  ? 180 PHE B CA    1 
ATOM   5265 C C     . PHE C 3 185 ? 127.827 127.049 71.866  1.00 22.00  ? 180 PHE B C     1 
ATOM   5266 O O     . PHE C 3 185 ? 127.856 126.992 73.102  1.00 22.00  ? 180 PHE B O     1 
ATOM   5267 C CB    . PHE C 3 185 ? 126.280 125.150 71.300  1.00 22.00  ? 180 PHE B CB    1 
ATOM   5268 C CG    . PHE C 3 185 ? 126.167 123.721 70.841  1.00 22.00  ? 180 PHE B CG    1 
ATOM   5269 C CD1   . PHE C 3 185 ? 126.719 122.692 71.586  1.00 22.00  ? 180 PHE B CD1   1 
ATOM   5270 C CD2   . PHE C 3 185 ? 125.497 123.407 69.673  1.00 22.00  ? 180 PHE B CD2   1 
ATOM   5271 C CE1   . PHE C 3 185 ? 126.613 121.381 71.169  1.00 22.00  ? 180 PHE B CE1   1 
ATOM   5272 C CE2   . PHE C 3 185 ? 125.386 122.096 69.254  1.00 22.00  ? 180 PHE B CE2   1 
ATOM   5273 C CZ    . PHE C 3 185 ? 125.945 121.083 70.003  1.00 22.00  ? 180 PHE B CZ    1 
ATOM   5274 N N     . THR C 3 186 ? 127.945 128.182 71.181  1.00 23.45  ? 181 THR B N     1 
ATOM   5275 C CA    . THR C 3 186 ? 128.139 129.482 71.801  1.00 23.45  ? 181 THR B CA    1 
ATOM   5276 C C     . THR C 3 186 ? 127.121 130.478 71.260  1.00 23.45  ? 181 THR B C     1 
ATOM   5277 O O     . THR C 3 186 ? 126.436 130.225 70.265  1.00 23.45  ? 181 THR B O     1 
ATOM   5278 C CB    . THR C 3 186 ? 129.558 130.005 71.550  1.00 23.45  ? 181 THR B CB    1 
ATOM   5279 O OG1   . THR C 3 186 ? 129.639 130.563 70.233  1.00 23.45  ? 181 THR B OG1   1 
ATOM   5280 C CG2   . THR C 3 186 ? 130.577 128.885 71.690  1.00 23.45  ? 181 THR B CG2   1 
ATOM   5281 N N     . GLY C 3 187 ? 127.032 131.621 71.934  1.00 27.42  ? 182 GLY B N     1 
ATOM   5282 C CA    . GLY C 3 187 ? 126.094 132.659 71.553  1.00 27.42  ? 182 GLY B CA    1 
ATOM   5283 C C     . GLY C 3 187 ? 125.460 133.334 72.751  1.00 27.42  ? 182 GLY B C     1 
ATOM   5284 O O     . GLY C 3 187 ? 125.032 134.489 72.669  1.00 27.42  ? 182 GLY B O     1 
ATOM   5285 N N     . HIS C 3 188 ? 125.392 132.621 73.870  1.00 24.13  ? 183 HIS B N     1 
ATOM   5286 C CA    . HIS C 3 188 ? 124.898 133.201 75.106  1.00 24.13  ? 183 HIS B CA    1 
ATOM   5287 C C     . HIS C 3 188 ? 125.894 134.222 75.648  1.00 24.13  ? 183 HIS B C     1 
ATOM   5288 O O     . HIS C 3 188 ? 127.101 134.146 75.404  1.00 24.13  ? 183 HIS B O     1 
ATOM   5289 C CB    . HIS C 3 188 ? 124.652 132.114 76.153  1.00 24.13  ? 183 HIS B CB    1 
ATOM   5290 C CG    . HIS C 3 188 ? 123.289 131.499 76.082  1.00 24.13  ? 183 HIS B CG    1 
ATOM   5291 N ND1   . HIS C 3 188 ? 122.135 132.251 76.036  1.00 24.13  ? 183 HIS B ND1   1 
ATOM   5292 C CD2   . HIS C 3 188 ? 122.896 130.204 76.055  1.00 24.13  ? 183 HIS B CD2   1 
ATOM   5293 C CE1   . HIS C 3 188 ? 121.090 131.445 75.984  1.00 24.13  ? 183 HIS B CE1   1 
ATOM   5294 N NE2   . HIS C 3 188 ? 121.524 130.198 75.992  1.00 24.13  ? 183 HIS B NE2   1 
ATOM   5295 N N     . THR C 3 189 ? 125.366 135.195 76.390  1.00 23.98  ? 184 THR B N     1 
ATOM   5296 C CA    . THR C 3 189 ? 126.184 136.186 77.071  1.00 23.98  ? 184 THR B CA    1 
ATOM   5297 C C     . THR C 3 189 ? 126.160 136.022 78.583  1.00 23.98  ? 184 THR B C     1 
ATOM   5298 O O     . THR C 3 189 ? 126.903 136.724 79.279  1.00 23.98  ? 184 THR B O     1 
ATOM   5299 C CB    . THR C 3 189 ? 125.725 137.603 76.705  1.00 23.98  ? 184 THR B CB    1 
ATOM   5300 O OG1   . THR C 3 189 ? 124.368 137.794 77.123  1.00 23.98  ? 184 THR B OG1   1 
ATOM   5301 C CG2   . THR C 3 189 ? 125.827 137.826 75.204  1.00 23.98  ? 184 THR B CG2   1 
ATOM   5302 N N     . GLY C 3 190 ? 125.333 135.117 79.109  1.00 21.84  ? 185 GLY B N     1 
ATOM   5303 C CA    . GLY C 3 190 ? 125.277 134.854 80.531  1.00 21.84  ? 185 GLY B CA    1 
ATOM   5304 C C     . GLY C 3 190 ? 125.349 133.363 80.811  1.00 21.84  ? 185 GLY B C     1 
ATOM   5305 O O     . GLY C 3 190 ? 125.331 132.536 79.897  1.00 21.84  ? 185 GLY B O     1 
ATOM   5306 N N     . ASP C 3 191 ? 125.431 133.044 82.098  1.00 19.17  ? 186 ASP B N     1 
ATOM   5307 C CA    . ASP C 3 191 ? 125.573 131.660 82.536  1.00 19.17  ? 186 ASP B CA    1 
ATOM   5308 C C     . ASP C 3 191 ? 124.377 130.847 82.055  1.00 19.17  ? 186 ASP B C     1 
ATOM   5309 O O     . ASP C 3 191 ? 123.225 131.202 82.322  1.00 19.17  ? 186 ASP B O     1 
ATOM   5310 C CB    . ASP C 3 191 ? 125.696 131.605 84.055  1.00 19.17  ? 186 ASP B CB    1 
ATOM   5311 C CG    . ASP C 3 191 ? 127.052 132.070 84.544  1.00 19.17  ? 186 ASP B CG    1 
ATOM   5312 O OD1   . ASP C 3 191 ? 127.766 132.737 83.766  1.00 19.17  ? 186 ASP B OD1   1 
ATOM   5313 O OD2   . ASP C 3 191 ? 127.404 131.773 85.704  1.00 19.17  ? 186 ASP B OD2   1 
ATOM   5314 N N     . VAL C 3 192 ? 124.648 129.755 81.342  1.00 18.26  ? 187 VAL B N     1 
ATOM   5315 C CA    . VAL C 3 192 ? 123.597 128.863 80.864  1.00 18.26  ? 187 VAL B CA    1 
ATOM   5316 C C     . VAL C 3 192 ? 123.216 127.930 82.006  1.00 18.26  ? 187 VAL B C     1 
ATOM   5317 O O     . VAL C 3 192 ? 124.075 127.240 82.567  1.00 18.26  ? 187 VAL B O     1 
ATOM   5318 C CB    . VAL C 3 192 ? 124.051 128.077 79.622  1.00 18.26  ? 187 VAL B CB    1 
ATOM   5319 C CG1   . VAL C 3 192 ? 122.869 127.420 78.963  1.00 18.26  ? 187 VAL B CG1   1 
ATOM   5320 C CG2   . VAL C 3 192 ? 124.763 128.991 78.644  1.00 18.26  ? 187 VAL B CG2   1 
ATOM   5321 N N     . MET C 3 193 ? 121.947 127.947 82.429  1.00 16.66  ? 188 MET B N     1 
ATOM   5322 C CA    . MET C 3 193 ? 121.531 127.235 83.671  1.00 16.66  ? 188 MET B CA    1 
ATOM   5323 C C     . MET C 3 193 ? 120.765 125.929 83.432  1.00 16.66  ? 188 MET B C     1 
ATOM   5324 O O     . MET C 3 193 ? 120.715 125.135 84.393  1.00 16.66  ? 188 MET B O     1 
ATOM   5325 C CB    . MET C 3 193 ? 120.641 128.173 84.490  1.00 16.66  ? 188 MET B CB    1 
ATOM   5326 C CG    . MET C 3 193 ? 121.407 129.007 85.499  1.00 16.66  ? 188 MET B CG    1 
ATOM   5327 S SD    . MET C 3 193 ? 121.863 128.070 86.978  1.00 16.66  ? 188 MET B SD    1 
ATOM   5328 C CE    . MET C 3 193 ? 120.262 127.920 87.767  1.00 16.66  ? 188 MET B CE    1 
ATOM   5329 N N     . SER C 3 194 ? 120.147 125.693 82.271  1.00 16.13  ? 189 SER B N     1 
ATOM   5330 C CA    . SER C 3 194 ? 119.373 124.472 82.105  1.00 16.13  ? 189 SER B CA    1 
ATOM   5331 C C     . SER C 3 194 ? 119.234 124.158 80.624  1.00 16.13  ? 189 SER B C     1 
ATOM   5332 O O     . SER C 3 194 ? 119.111 125.067 79.800  1.00 16.13  ? 189 SER B O     1 
ATOM   5333 C CB    . SER C 3 194 ? 117.991 124.606 82.753  1.00 16.13  ? 189 SER B CB    1 
ATOM   5334 O OG    . SER C 3 194 ? 117.299 123.370 82.739  1.00 16.13  ? 189 SER B OG    1 
ATOM   5335 N N     . LEU C 3 195 ? 119.261 122.868 80.300  1.00 14.80  ? 190 LEU B N     1 
ATOM   5336 C CA    . LEU C 3 195 ? 119.042 122.395 78.942  1.00 14.80  ? 190 LEU B CA    1 
ATOM   5337 C C     . LEU C 3 195 ? 118.048 121.248 78.984  1.00 14.80  ? 190 LEU B C     1 
ATOM   5338 O O     . LEU C 3 195 ? 118.000 120.494 79.959  1.00 14.80  ? 190 LEU B O     1 
ATOM   5339 C CB    . LEU C 3 195 ? 120.349 121.932 78.281  1.00 14.80  ? 190 LEU B CB    1 
ATOM   5340 C CG    . LEU C 3 195 ? 121.055 120.722 78.903  1.00 14.80  ? 190 LEU B CG    1 
ATOM   5341 C CD1   . LEU C 3 195 ? 120.523 119.401 78.344  1.00 14.80  ? 190 LEU B CD1   1 
ATOM   5342 C CD2   . LEU C 3 195 ? 122.557 120.822 78.707  1.00 14.80  ? 190 LEU B CD2   1 
ATOM   5343 N N     . SER C 3 196 ? 117.254 121.126 77.926  1.00 15.87  ? 191 SER B N     1 
ATOM   5344 C CA    . SER C 3 196 ? 116.317 120.024 77.763  1.00 15.87  ? 191 SER B CA    1 
ATOM   5345 C C     . SER C 3 196 ? 116.599 119.363 76.424  1.00 15.87  ? 191 SER B C     1 
ATOM   5346 O O     . SER C 3 196 ? 116.874 120.051 75.437  1.00 15.87  ? 191 SER B O     1 
ATOM   5347 C CB    . SER C 3 196 ? 114.870 120.515 77.834  1.00 15.87  ? 191 SER B CB    1 
ATOM   5348 O OG    . SER C 3 196 ? 113.958 119.432 77.827  1.00 15.87  ? 191 SER B OG    1 
ATOM   5349 N N     . LEU C 3 197 ? 116.560 118.035 76.398  1.00 15.92  ? 192 LEU B N     1 
ATOM   5350 C CA    . LEU C 3 197 ? 116.759 117.301 75.158  1.00 15.92  ? 192 LEU B CA    1 
ATOM   5351 C C     . LEU C 3 197 ? 115.419 117.014 74.497  1.00 15.92  ? 192 LEU B C     1 
ATOM   5352 O O     . LEU C 3 197 ? 114.446 116.652 75.163  1.00 15.92  ? 192 LEU B O     1 
ATOM   5353 C CB    . LEU C 3 197 ? 117.498 115.990 75.421  1.00 15.92  ? 192 LEU B CB    1 
ATOM   5354 C CG    . LEU C 3 197 ? 119.004 115.987 75.157  1.00 15.92  ? 192 LEU B CG    1 
ATOM   5355 C CD1   . LEU C 3 197 ? 119.593 114.647 75.554  1.00 15.92  ? 192 LEU B CD1   1 
ATOM   5356 C CD2   . LEU C 3 197 ? 119.320 116.296 73.701  1.00 15.92  ? 192 LEU B CD2   1 
ATOM   5357 N N     . ALA C 3 198 ? 115.374 117.177 73.180  1.00 22.00  ? 193 ALA B N     1 
ATOM   5358 C CA    . ALA C 3 198 ? 114.158 116.904 72.443  1.00 22.00  ? 193 ALA B CA    1 
ATOM   5359 C C     . ALA C 3 198 ? 113.848 115.410 72.477  1.00 22.00  ? 193 ALA B C     1 
ATOM   5360 O O     . ALA C 3 198 ? 114.747 114.583 72.647  1.00 22.00  ? 193 ALA B O     1 
ATOM   5361 C CB    . ALA C 3 198 ? 114.293 117.383 71.001  1.00 22.00  ? 193 ALA B CB    1 
ATOM   5362 N N     . PRO C 3 199 ? 112.575 115.037 72.325  1.00 26.70  ? 194 PRO B N     1 
ATOM   5363 C CA    . PRO C 3 199 ? 112.233 113.604 72.345  1.00 26.70  ? 194 PRO B CA    1 
ATOM   5364 C C     . PRO C 3 199 ? 113.003 112.787 71.322  1.00 26.70  ? 194 PRO B C     1 
ATOM   5365 O O     . PRO C 3 199 ? 113.370 111.639 71.603  1.00 26.70  ? 194 PRO B O     1 
ATOM   5366 C CB    . PRO C 3 199 ? 110.722 113.596 72.058  1.00 26.70  ? 194 PRO B CB    1 
ATOM   5367 C CG    . PRO C 3 199 ? 110.383 114.978 71.586  1.00 26.70  ? 194 PRO B CG    1 
ATOM   5368 C CD    . PRO C 3 199 ? 111.380 115.887 72.212  1.00 26.70  ? 194 PRO B CD    1 
ATOM   5369 N N     . ASP C 3 200 ? 113.261 113.346 70.138  1.00 26.77  ? 195 ASP B N     1 
ATOM   5370 C CA    . ASP C 3 200 ? 114.017 112.638 69.113  1.00 26.77  ? 195 ASP B CA    1 
ATOM   5371 C C     . ASP C 3 200 ? 115.523 112.818 69.257  1.00 26.77  ? 195 ASP B C     1 
ATOM   5372 O O     . ASP C 3 200 ? 116.274 112.265 68.447  1.00 26.77  ? 195 ASP B O     1 
ATOM   5373 C CB    . ASP C 3 200 ? 113.575 113.099 67.720  1.00 26.77  ? 195 ASP B CB    1 
ATOM   5374 C CG    . ASP C 3 200 ? 113.851 114.570 67.473  1.00 26.77  ? 195 ASP B CG    1 
ATOM   5375 O OD1   . ASP C 3 200 ? 114.347 115.253 68.393  1.00 26.77  ? 195 ASP B OD1   1 
ATOM   5376 O OD2   . ASP C 3 200 ? 113.573 115.044 66.351  1.00 26.77  ? 195 ASP B OD2   1 
ATOM   5377 N N     . THR C 3 201 ? 115.979 113.571 70.259  1.00 23.56  ? 196 THR B N     1 
ATOM   5378 C CA    . THR C 3 201 ? 117.408 113.742 70.523  1.00 23.56  ? 196 THR B CA    1 
ATOM   5379 C C     . THR C 3 201 ? 118.132 114.324 69.311  1.00 23.56  ? 196 THR B C     1 
ATOM   5380 O O     . THR C 3 201 ? 119.273 113.965 69.015  1.00 23.56  ? 196 THR B O     1 
ATOM   5381 C CB    . THR C 3 201 ? 118.048 112.417 70.946  1.00 23.56  ? 196 THR B CB    1 
ATOM   5382 O OG1   . THR C 3 201 ? 118.094 111.524 69.827  1.00 23.56  ? 196 THR B OG1   1 
ATOM   5383 C CG2   . THR C 3 201 ? 117.260 111.776 72.080  1.00 23.56  ? 196 THR B CG2   1 
ATOM   5384 N N     . ARG C 3 202 ? 117.464 115.238 68.605  1.00 29.19  ? 197 ARG B N     1 
ATOM   5385 C CA    . ARG C 3 202 ? 118.037 115.889 67.437  1.00 29.19  ? 197 ARG B CA    1 
ATOM   5386 C C     . ARG C 3 202 ? 118.276 117.379 67.635  1.00 29.19  ? 197 ARG B C     1 
ATOM   5387 O O     . ARG C 3 202 ? 119.029 117.973 66.855  1.00 29.19  ? 197 ARG B O     1 
ATOM   5388 C CB    . ARG C 3 202 ? 117.129 115.677 66.214  1.00 29.19  ? 197 ARG B CB    1 
ATOM   5389 C CG    . ARG C 3 202 ? 117.702 116.190 64.902  1.00 29.19  ? 197 ARG B CG    1 
ATOM   5390 C CD    . ARG C 3 202 ? 116.740 115.951 63.750  1.00 29.19  ? 197 ARG B CD    1 
ATOM   5391 N NE    . ARG C 3 202 ? 116.635 114.537 63.408  1.00 29.19  ? 197 ARG B NE    1 
ATOM   5392 C CZ    . ARG C 3 202 ? 117.452 113.897 62.582  1.00 29.19  ? 197 ARG B CZ    1 
ATOM   5393 N NH1   . ARG C 3 202 ? 118.460 114.515 61.987  1.00 29.19  ? 197 ARG B NH1   1 
ATOM   5394 N NH2   . ARG C 3 202 ? 117.254 112.603 62.346  1.00 29.19  ? 197 ARG B NH2   1 
ATOM   5395 N N     . LEU C 3 203 ? 117.673 117.994 68.649  1.00 26.53  ? 198 LEU B N     1 
ATOM   5396 C CA    . LEU C 3 203 ? 117.893 119.400 68.956  1.00 26.53  ? 198 LEU B CA    1 
ATOM   5397 C C     . LEU C 3 203 ? 117.956 119.549 70.468  1.00 26.53  ? 198 LEU B C     1 
ATOM   5398 O O     . LEU C 3 203 ? 117.916 118.565 71.209  1.00 26.53  ? 198 LEU B O     1 
ATOM   5399 C CB    . LEU C 3 203 ? 116.780 120.284 68.381  1.00 26.53  ? 198 LEU B CB    1 
ATOM   5400 C CG    . LEU C 3 203 ? 116.479 120.156 66.887  1.00 26.53  ? 198 LEU B CG    1 
ATOM   5401 C CD1   . LEU C 3 203 ? 115.156 120.827 66.564  1.00 26.53  ? 198 LEU B CD1   1 
ATOM   5402 C CD2   . LEU C 3 203 ? 117.595 120.751 66.051  1.00 26.53  ? 198 LEU B CD2   1 
ATOM   5403 N N     . PHE C 3 204 ? 118.059 120.794 70.926  1.00 21.11  ? 199 PHE B N     1 
ATOM   5404 C CA    . PHE C 3 204 ? 117.839 121.068 72.340  1.00 21.11  ? 199 PHE B CA    1 
ATOM   5405 C C     . PHE C 3 204 ? 117.598 122.558 72.520  1.00 21.11  ? 199 PHE B C     1 
ATOM   5406 O O     . PHE C 3 204 ? 117.833 123.355 71.612  1.00 21.11  ? 199 PHE B O     1 
ATOM   5407 C CB    . PHE C 3 204 ? 119.008 120.580 73.206  1.00 21.11  ? 199 PHE B CB    1 
ATOM   5408 C CG    . PHE C 3 204 ? 120.311 121.264 72.924  1.00 21.11  ? 199 PHE B CG    1 
ATOM   5409 C CD1   . PHE C 3 204 ? 121.009 121.004 71.758  1.00 21.11  ? 199 PHE B CD1   1 
ATOM   5410 C CD2   . PHE C 3 204 ? 120.850 122.151 73.837  1.00 21.11  ? 199 PHE B CD2   1 
ATOM   5411 C CE1   . PHE C 3 204 ? 122.212 121.628 71.502  1.00 21.11  ? 199 PHE B CE1   1 
ATOM   5412 C CE2   . PHE C 3 204 ? 122.052 122.778 73.587  1.00 21.11  ? 199 PHE B CE2   1 
ATOM   5413 C CZ    . PHE C 3 204 ? 122.735 122.515 72.420  1.00 21.11  ? 199 PHE B CZ    1 
ATOM   5414 N N     . VAL C 3 205 ? 117.086 122.918 73.693  1.00 20.20  ? 200 VAL B N     1 
ATOM   5415 C CA    . VAL C 3 205 ? 116.831 124.306 74.056  1.00 20.20  ? 200 VAL B CA    1 
ATOM   5416 C C     . VAL C 3 205 ? 117.505 124.573 75.390  1.00 20.20  ? 200 VAL B C     1 
ATOM   5417 O O     . VAL C 3 205 ? 117.518 123.708 76.273  1.00 20.20  ? 200 VAL B O     1 
ATOM   5418 C CB    . VAL C 3 205 ? 115.323 124.626 74.139  1.00 20.20  ? 200 VAL B CB    1 
ATOM   5419 C CG1   . VAL C 3 205 ? 114.675 124.512 72.767  1.00 20.20  ? 200 VAL B CG1   1 
ATOM   5420 C CG2   . VAL C 3 205 ? 114.633 123.732 75.161  1.00 20.20  ? 200 VAL B CG2   1 
ATOM   5421 N N     . SER C 3 206 ? 118.073 125.766 75.533  1.00 20.26  ? 201 SER B N     1 
ATOM   5422 C CA    . SER C 3 206 ? 118.795 126.131 76.742  1.00 20.26  ? 201 SER B CA    1 
ATOM   5423 C C     . SER C 3 206 ? 118.558 127.597 77.074  1.00 20.26  ? 201 SER B C     1 
ATOM   5424 O O     . SER C 3 206 ? 118.542 128.450 76.182  1.00 20.26  ? 201 SER B O     1 
ATOM   5425 C CB    . SER C 3 206 ? 120.289 125.865 76.584  1.00 20.26  ? 201 SER B CB    1 
ATOM   5426 O OG    . SER C 3 206 ? 120.931 125.881 77.841  1.00 20.26  ? 201 SER B OG    1 
ATOM   5427 N N     . GLY C 3 207 ? 118.369 127.877 78.362  1.00 18.91  ? 202 GLY B N     1 
ATOM   5428 C CA    . GLY C 3 207 ? 118.190 129.229 78.856  1.00 18.91  ? 202 GLY B CA    1 
ATOM   5429 C C     . GLY C 3 207 ? 119.400 129.666 79.659  1.00 18.91  ? 202 GLY B C     1 
ATOM   5430 O O     . GLY C 3 207 ? 120.051 128.848 80.318  1.00 18.91  ? 202 GLY B O     1 
ATOM   5431 N N     . ALA C 3 208 ? 119.701 130.962 79.609  1.00 20.21  ? 203 ALA B N     1 
ATOM   5432 C CA    . ALA C 3 208 ? 120.904 131.485 80.237  1.00 20.21  ? 203 ALA B CA    1 
ATOM   5433 C C     . ALA C 3 208 ? 120.563 132.644 81.161  1.00 20.21  ? 203 ALA B C     1 
ATOM   5434 O O     . ALA C 3 208 ? 119.432 133.137 81.197  1.00 20.21  ? 203 ALA B O     1 
ATOM   5435 C CB    . ALA C 3 208 ? 121.931 131.930 79.188  1.00 20.21  ? 203 ALA B CB    1 
ATOM   5436 N N     . CYS C 3 209 ? 121.573 133.073 81.919  1.00 22.43  ? 204 CYS B N     1 
ATOM   5437 C CA    . CYS C 3 209 ? 121.435 134.203 82.827  1.00 22.43  ? 204 CYS B CA    1 
ATOM   5438 C C     . CYS C 3 209 ? 121.337 135.532 82.098  1.00 22.43  ? 204 CYS B C     1 
ATOM   5439 O O     . CYS C 3 209 ? 121.077 136.552 82.744  1.00 22.43  ? 204 CYS B O     1 
ATOM   5440 C CB    . CYS C 3 209 ? 122.606 134.233 83.809  1.00 22.43  ? 204 CYS B CB    1 
ATOM   5441 S SG    . CYS C 3 209 ? 122.419 133.096 85.198  1.00 22.43  ? 204 CYS B SG    1 
ATOM   5442 N N     . ASP C 3 210 ? 121.537 135.548 80.783  1.00 22.55  ? 205 ASP B N     1 
ATOM   5443 C CA    . ASP C 3 210 ? 121.283 136.726 79.969  1.00 22.55  ? 205 ASP B CA    1 
ATOM   5444 C C     . ASP C 3 210 ? 119.794 136.970 79.750  1.00 22.55  ? 205 ASP B C     1 
ATOM   5445 O O     . ASP C 3 210 ? 119.430 137.801 78.912  1.00 22.55  ? 205 ASP B O     1 
ATOM   5446 C CB    . ASP C 3 210 ? 121.999 136.597 78.621  1.00 22.55  ? 205 ASP B CB    1 
ATOM   5447 C CG    . ASP C 3 210 ? 121.348 135.575 77.703  1.00 22.55  ? 205 ASP B CG    1 
ATOM   5448 O OD1   . ASP C 3 210 ? 120.520 134.772 78.182  1.00 22.55  ? 205 ASP B OD1   1 
ATOM   5449 O OD2   . ASP C 3 210 ? 121.669 135.572 76.496  1.00 22.55  ? 205 ASP B OD2   1 
ATOM   5450 N N     . ALA C 3 211 ? 118.930 136.261 80.480  1.00 23.35  ? 206 ALA B N     1 
ATOM   5451 C CA    . ALA C 3 211 ? 117.482 136.425 80.380  1.00 23.35  ? 206 ALA B CA    1 
ATOM   5452 C C     . ALA C 3 211 ? 116.968 136.041 78.998  1.00 23.35  ? 206 ALA B C     1 
ATOM   5453 O O     . ALA C 3 211 ? 115.964 136.578 78.527  1.00 23.35  ? 206 ALA B O     1 
ATOM   5454 C CB    . ALA C 3 211 ? 117.062 137.856 80.724  1.00 23.35  ? 206 ALA B CB    1 
ATOM   5455 N N     . SER C 3 212 ? 117.650 135.109 78.338  1.00 24.34  ? 207 SER B N     1 
ATOM   5456 C CA    . SER C 3 212 ? 117.263 134.655 77.013  1.00 24.34  ? 207 SER B CA    1 
ATOM   5457 C C     . SER C 3 212 ? 117.396 133.142 76.921  1.00 24.34  ? 207 SER B C     1 
ATOM   5458 O O     . SER C 3 212 ? 118.261 132.533 77.562  1.00 24.34  ? 207 SER B O     1 
ATOM   5459 C CB    . SER C 3 212 ? 118.120 135.312 75.925  1.00 24.34  ? 207 SER B CB    1 
ATOM   5460 O OG    . SER C 3 212 ? 119.354 134.635 75.773  1.00 24.34  ? 207 SER B OG    1 
ATOM   5461 N N     . ALA C 3 213 ? 116.528 132.545 76.108  1.00 25.99  ? 208 ALA B N     1 
ATOM   5462 C CA    . ALA C 3 213 ? 116.596 131.130 75.788  1.00 25.99  ? 208 ALA B CA    1 
ATOM   5463 C C     . ALA C 3 213 ? 116.970 130.986 74.322  1.00 25.99  ? 208 ALA B C     1 
ATOM   5464 O O     . ALA C 3 213 ? 116.981 131.961 73.569  1.00 25.99  ? 208 ALA B O     1 
ATOM   5465 C CB    . ALA C 3 213 ? 115.263 130.425 76.069  1.00 25.99  ? 208 ALA B CB    1 
ATOM   5466 N N     . LYS C 3 214 ? 117.292 129.765 73.910  1.00 28.29  ? 209 LYS B N     1 
ATOM   5467 C CA    . LYS C 3 214 ? 117.591 129.551 72.503  1.00 28.29  ? 209 LYS B CA    1 
ATOM   5468 C C     . LYS C 3 214 ? 117.604 128.069 72.168  1.00 28.29  ? 209 LYS B C     1 
ATOM   5469 O O     . LYS C 3 214 ? 117.937 127.220 73.001  1.00 28.29  ? 209 LYS B O     1 
ATOM   5470 C CB    . LYS C 3 214 ? 118.925 130.196 72.117  1.00 28.29  ? 209 LYS B CB    1 
ATOM   5471 C CG    . LYS C 3 214 ? 120.064 129.879 73.056  1.00 28.29  ? 209 LYS B CG    1 
ATOM   5472 C CD    . LYS C 3 214 ? 121.365 130.492 72.569  1.00 28.29  ? 209 LYS B CD    1 
ATOM   5473 C CE    . LYS C 3 214 ? 121.306 132.012 72.524  1.00 28.29  ? 209 LYS B CE    1 
ATOM   5474 N NZ    . LYS C 3 214 ? 122.607 132.592 72.111  1.00 28.29  ? 209 LYS B NZ    1 
ATOM   5475 N N     . LEU C 3 215 ? 117.248 127.784 70.919  1.00 30.08  ? 210 LEU B N     1 
ATOM   5476 C CA    . LEU C 3 215 ? 117.214 126.436 70.374  1.00 30.08  ? 210 LEU B CA    1 
ATOM   5477 C C     . LEU C 3 215 ? 118.479 126.208 69.559  1.00 30.08  ? 210 LEU B C     1 
ATOM   5478 O O     . LEU C 3 215 ? 118.740 126.935 68.591  1.00 30.08  ? 210 LEU B O     1 
ATOM   5479 C CB    . LEU C 3 215 ? 115.970 126.234 69.509  1.00 30.08  ? 210 LEU B CB    1 
ATOM   5480 C CG    . LEU C 3 215 ? 115.993 125.073 68.513  1.00 30.08  ? 210 LEU B CG    1 
ATOM   5481 C CD1   . LEU C 3 215 ? 116.122 123.749 69.239  1.00 30.08  ? 210 LEU B CD1   1 
ATOM   5482 C CD2   . LEU C 3 215 ? 114.743 125.092 67.656  1.00 30.08  ? 210 LEU B CD2   1 
ATOM   5483 N N     . TRP C 3 216 ? 119.247 125.195 69.952  1.00 27.20  ? 211 TRP B N     1 
ATOM   5484 C CA    . TRP C 3 216 ? 120.504 124.833 69.319  1.00 27.20  ? 211 TRP B CA    1 
ATOM   5485 C C     . TRP C 3 216 ? 120.382 123.449 68.693  1.00 27.20  ? 211 TRP B C     1 
ATOM   5486 O O     . TRP C 3 216 ? 119.897 122.506 69.334  1.00 27.20  ? 211 TRP B O     1 
ATOM   5487 C CB    . TRP C 3 216 ? 121.645 124.861 70.342  1.00 27.20  ? 211 TRP B CB    1 
ATOM   5488 C CG    . TRP C 3 216 ? 122.228 126.232 70.572  1.00 27.20  ? 211 TRP B CG    1 
ATOM   5489 C CD1   . TRP C 3 216 ? 122.081 127.324 69.775  1.00 27.20  ? 211 TRP B CD1   1 
ATOM   5490 C CD2   . TRP C 3 216 ? 123.051 126.650 71.669  1.00 27.20  ? 211 TRP B CD2   1 
ATOM   5491 N NE1   . TRP C 3 216 ? 122.760 128.394 70.297  1.00 27.20  ? 211 TRP B NE1   1 
ATOM   5492 C CE2   . TRP C 3 216 ? 123.364 128.008 71.462  1.00 27.20  ? 211 TRP B CE2   1 
ATOM   5493 C CE3   . TRP C 3 216 ? 123.554 126.010 72.805  1.00 27.20  ? 211 TRP B CE3   1 
ATOM   5494 C CZ2   . TRP C 3 216 ? 124.155 128.736 72.346  1.00 27.20  ? 211 TRP B CZ2   1 
ATOM   5495 C CZ3   . TRP C 3 216 ? 124.340 126.739 73.682  1.00 27.20  ? 211 TRP B CZ3   1 
ATOM   5496 C CH2   . TRP C 3 216 ? 124.631 128.085 73.448  1.00 27.20  ? 211 TRP B CH2   1 
ATOM   5497 N N     . ASP C 3 217 ? 120.818 123.339 67.438  1.00 32.56  ? 212 ASP B N     1 
ATOM   5498 C CA    . ASP C 3 217 ? 120.819 122.074 66.713  1.00 32.56  ? 212 ASP B CA    1 
ATOM   5499 C C     . ASP C 3 217 ? 122.068 121.279 67.076  1.00 32.56  ? 212 ASP B C     1 
ATOM   5500 O O     . ASP C 3 217 ? 123.185 121.806 67.021  1.00 32.56  ? 212 ASP B O     1 
ATOM   5501 C CB    . ASP C 3 217 ? 120.763 122.330 65.208  1.00 32.56  ? 212 ASP B CB    1 
ATOM   5502 C CG    . ASP C 3 217 ? 120.443 121.081 64.413  1.00 32.56  ? 212 ASP B CG    1 
ATOM   5503 O OD1   . ASP C 3 217 ? 121.248 120.127 64.451  1.00 32.56  ? 212 ASP B OD1   1 
ATOM   5504 O OD2   . ASP C 3 217 ? 119.388 121.053 63.746  1.00 32.56  ? 212 ASP B OD2   1 
ATOM   5505 N N     . VAL C 3 218 ? 121.881 120.009 67.440  1.00 25.92  ? 213 VAL B N     1 
ATOM   5506 C CA    . VAL C 3 218 ? 122.994 119.198 67.920  1.00 25.92  ? 213 VAL B CA    1 
ATOM   5507 C C     . VAL C 3 218 ? 123.919 118.761 66.793  1.00 25.92  ? 213 VAL B C     1 
ATOM   5508 O O     . VAL C 3 218 ? 125.106 118.517 67.034  1.00 25.92  ? 213 VAL B O     1 
ATOM   5509 C CB    . VAL C 3 218 ? 122.464 117.967 68.678  1.00 25.92  ? 213 VAL B CB    1 
ATOM   5510 C CG1   . VAL C 3 218 ? 121.740 117.028 67.727  1.00 25.92  ? 213 VAL B CG1   1 
ATOM   5511 C CG2   . VAL C 3 218 ? 123.602 117.247 69.381  1.00 25.92  ? 213 VAL B CG2   1 
ATOM   5512 N N     . ARG C 3 219 ? 123.413 118.652 65.565  1.00 32.90  ? 214 ARG B N     1 
ATOM   5513 C CA    . ARG C 3 219 ? 124.211 118.134 64.460  1.00 32.90  ? 214 ARG B CA    1 
ATOM   5514 C C     . ARG C 3 219 ? 125.140 119.190 63.868  1.00 32.90  ? 214 ARG B C     1 
ATOM   5515 O O     . ARG C 3 219 ? 126.358 118.995 63.827  1.00 32.90  ? 214 ARG B O     1 
ATOM   5516 C CB    . ARG C 3 219 ? 123.293 117.577 63.367  1.00 32.90  ? 214 ARG B CB    1 
ATOM   5517 C CG    . ARG C 3 219 ? 122.184 116.672 63.880  1.00 32.90  ? 214 ARG B CG    1 
ATOM   5518 C CD    . ARG C 3 219 ? 121.330 116.146 62.737  1.00 32.90  ? 214 ARG B CD    1 
ATOM   5519 N NE    . ARG C 3 219 ? 121.815 114.868 62.228  1.00 32.90  ? 214 ARG B NE    1 
ATOM   5520 C CZ    . ARG C 3 219 ? 121.727 113.716 62.881  1.00 32.90  ? 214 ARG B CZ    1 
ATOM   5521 N NH1   . ARG C 3 219 ? 121.169 113.640 64.078  1.00 32.90  ? 214 ARG B NH1   1 
ATOM   5522 N NH2   . ARG C 3 219 ? 122.211 112.613 62.317  1.00 32.90  ? 214 ARG B NH2   1 
ATOM   5523 N N     . GLU C 3 220 ? 124.585 120.312 63.413  1.00 39.50  ? 215 GLU B N     1 
ATOM   5524 C CA    . GLU C 3 220 ? 125.365 121.330 62.723  1.00 39.50  ? 215 GLU B CA    1 
ATOM   5525 C C     . GLU C 3 220 ? 126.124 122.252 63.668  1.00 39.50  ? 215 GLU B C     1 
ATOM   5526 O O     . GLU C 3 220 ? 126.996 122.997 63.209  1.00 39.50  ? 215 GLU B O     1 
ATOM   5527 C CB    . GLU C 3 220 ? 124.451 122.174 61.827  1.00 39.50  ? 215 GLU B CB    1 
ATOM   5528 C CG    . GLU C 3 220 ? 124.335 121.667 60.396  1.00 39.50  ? 215 GLU B CG    1 
ATOM   5529 C CD    . GLU C 3 220 ? 123.195 120.682 60.211  1.00 39.50  ? 215 GLU B CD    1 
ATOM   5530 O OE1   . GLU C 3 220 ? 122.651 120.197 61.225  1.00 39.50  ? 215 GLU B OE1   1 
ATOM   5531 O OE2   . GLU C 3 220 ? 122.842 120.392 59.048  1.00 39.50  ? 215 GLU B OE2   1 
ATOM   5532 N N     . GLY C 3 221 ? 125.823 122.224 64.963  1.00 34.24  ? 216 GLY B N     1 
ATOM   5533 C CA    . GLY C 3 221 ? 126.487 123.120 65.890  1.00 34.24  ? 216 GLY B CA    1 
ATOM   5534 C C     . GLY C 3 221 ? 126.169 124.580 65.673  1.00 34.24  ? 216 GLY B C     1 
ATOM   5535 O O     . GLY C 3 221 ? 126.843 125.444 66.239  1.00 34.24  ? 216 GLY B O     1 
ATOM   5536 N N     . MET C 3 222 ? 125.154 124.881 64.870  1.00 41.96  ? 217 MET B N     1 
ATOM   5537 C CA    . MET C 3 222 ? 124.759 126.248 64.570  1.00 41.96  ? 217 MET B CA    1 
ATOM   5538 C C     . MET C 3 222 ? 123.653 126.691 65.517  1.00 41.96  ? 217 MET B C     1 
ATOM   5539 O O     . MET C 3 222 ? 122.911 125.869 66.063  1.00 41.96  ? 217 MET B O     1 
ATOM   5540 C CB    . MET C 3 222 ? 124.278 126.369 63.123  1.00 41.96  ? 217 MET B CB    1 
ATOM   5541 C CG    . MET C 3 222 ? 122.922 125.725 62.874  1.00 41.96  ? 217 MET B CG    1 
ATOM   5542 S SD    . MET C 3 222 ? 122.638 125.312 61.142  1.00 41.96  ? 217 MET B SD    1 
ATOM   5543 C CE    . MET C 3 222 ? 121.306 124.124 61.295  1.00 41.96  ? 217 MET B CE    1 
ATOM   5544 N N     . CYS C 3 223 ? 123.548 128.003 65.709  1.00 41.85  ? 218 CYS B N     1 
ATOM   5545 C CA    . CYS C 3 223 ? 122.518 128.572 66.575  1.00 41.85  ? 218 CYS B CA    1 
ATOM   5546 C C     . CYS C 3 223 ? 121.230 128.688 65.773  1.00 41.85  ? 218 CYS B C     1 
ATOM   5547 O O     . CYS C 3 223 ? 121.050 129.626 64.993  1.00 41.85  ? 218 CYS B O     1 
ATOM   5548 C CB    . CYS C 3 223 ? 122.962 129.923 67.123  1.00 41.85  ? 218 CYS B CB    1 
ATOM   5549 S SG    . CYS C 3 223 ? 121.859 130.613 68.380  1.00 41.85  ? 218 CYS B SG    1 
ATOM   5550 N N     . ARG C 3 224 ? 120.322 127.727 65.961  1.00 38.80  ? 219 ARG B N     1 
ATOM   5551 C CA    . ARG C 3 224 ? 119.117 127.693 65.140  1.00 38.80  ? 219 ARG B CA    1 
ATOM   5552 C C     . ARG C 3 224 ? 118.186 128.856 65.457  1.00 38.80  ? 219 ARG B C     1 
ATOM   5553 O O     . ARG C 3 224 ? 117.744 129.563 64.544  1.00 38.80  ? 219 ARG B O     1 
ATOM   5554 C CB    . ARG C 3 224 ? 118.385 126.365 65.321  1.00 38.80  ? 219 ARG B CB    1 
ATOM   5555 C CG    . ARG C 3 224 ? 117.690 125.887 64.055  1.00 38.80  ? 219 ARG B CG    1 
ATOM   5556 C CD    . ARG C 3 224 ? 116.435 125.094 64.365  1.00 38.80  ? 219 ARG B CD    1 
ATOM   5557 N NE    . ARG C 3 224 ? 116.032 124.247 63.248  1.00 38.80  ? 219 ARG B NE    1 
ATOM   5558 C CZ    . ARG C 3 224 ? 115.227 124.630 62.265  1.00 38.80  ? 219 ARG B CZ    1 
ATOM   5559 N NH1   . ARG C 3 224 ? 114.726 125.854 62.215  1.00 38.80  ? 219 ARG B NH1   1 
ATOM   5560 N NH2   . ARG C 3 224 ? 114.917 123.762 61.306  1.00 38.80  ? 219 ARG B NH2   1 
ATOM   5561 N N     . GLN C 3 225 ? 117.880 129.082 66.733  1.00 40.79  ? 220 GLN B N     1 
ATOM   5562 C CA    . GLN C 3 225 ? 116.922 130.123 67.084  1.00 40.79  ? 220 GLN B CA    1 
ATOM   5563 C C     . GLN C 3 225 ? 117.243 130.684 68.460  1.00 40.79  ? 220 GLN B C     1 
ATOM   5564 O O     . GLN C 3 225 ? 117.911 130.048 69.275  1.00 40.79  ? 220 GLN B O     1 
ATOM   5565 C CB    . GLN C 3 225 ? 115.484 129.598 67.065  1.00 40.79  ? 220 GLN B CB    1 
ATOM   5566 C CG    . GLN C 3 225 ? 114.824 129.619 65.701  1.00 40.79  ? 220 GLN B CG    1 
ATOM   5567 C CD    . GLN C 3 225 ? 113.563 128.785 65.663  1.00 40.79  ? 220 GLN B CD    1 
ATOM   5568 O OE1   . GLN C 3 225 ? 113.453 127.835 64.888  1.00 40.79  ? 220 GLN B OE1   1 
ATOM   5569 N NE2   . GLN C 3 225 ? 112.602 129.135 66.507  1.00 40.79  ? 220 GLN B NE2   1 
ATOM   5570 N N     . THR C 3 226 ? 116.718 131.881 68.719  1.00 41.07  ? 221 THR B N     1 
ATOM   5571 C CA    . THR C 3 226 ? 116.856 132.533 70.015  1.00 41.07  ? 221 THR B CA    1 
ATOM   5572 C C     . THR C 3 226 ? 115.516 133.147 70.394  1.00 41.07  ? 221 THR B C     1 
ATOM   5573 O O     . THR C 3 226 ? 114.811 133.678 69.532  1.00 41.07  ? 221 THR B O     1 
ATOM   5574 C CB    . THR C 3 226 ? 117.951 133.606 69.984  1.00 41.07  ? 221 THR B CB    1 
ATOM   5575 O OG1   . THR C 3 226 ? 118.353 133.923 71.323  1.00 41.07  ? 221 THR B OG1   1 
ATOM   5576 C CG2   . THR C 3 226 ? 117.459 134.868 69.285  1.00 41.07  ? 221 THR B CG2   1 
ATOM   5577 N N     . PHE C 3 227 ? 115.168 133.062 71.675  1.00 34.40  ? 222 PHE B N     1 
ATOM   5578 C CA    . PHE C 3 227 ? 113.918 133.578 72.203  1.00 34.40  ? 222 PHE B CA    1 
ATOM   5579 C C     . PHE C 3 227 ? 114.202 134.531 73.355  1.00 34.40  ? 222 PHE B C     1 
ATOM   5580 O O     . PHE C 3 227 ? 115.050 134.272 74.219  1.00 34.40  ? 222 PHE B O     1 
ATOM   5581 C CB    . PHE C 3 227 ? 113.000 132.448 72.694  1.00 34.40  ? 222 PHE B CB    1 
ATOM   5582 C CG    . PHE C 3 227 ? 112.881 131.297 71.737  1.00 34.40  ? 222 PHE B CG    1 
ATOM   5583 C CD1   . PHE C 3 227 ? 113.867 130.325 71.674  1.00 34.40  ? 222 PHE B CD1   1 
ATOM   5584 C CD2   . PHE C 3 227 ? 111.781 131.184 70.904  1.00 34.40  ? 222 PHE B CD2   1 
ATOM   5585 C CE1   . PHE C 3 227 ? 113.758 129.265 70.798  1.00 34.40  ? 222 PHE B CE1   1 
ATOM   5586 C CE2   . PHE C 3 227 ? 111.668 130.128 70.026  1.00 34.40  ? 222 PHE B CE2   1 
ATOM   5587 C CZ    . PHE C 3 227 ? 112.658 129.167 69.972  1.00 34.40  ? 222 PHE B CZ    1 
ATOM   5588 N N     . THR C 3 228 ? 113.451 135.632 73.368  1.00 40.82  ? 223 THR B N     1 
ATOM   5589 C CA    . THR C 3 228 ? 113.613 136.679 74.369  1.00 40.82  ? 223 THR B CA    1 
ATOM   5590 C C     . THR C 3 228 ? 112.246 137.161 74.835  1.00 40.82  ? 223 THR B C     1 
ATOM   5591 O O     . THR C 3 228 ? 111.230 136.508 74.576  1.00 40.82  ? 223 THR B O     1 
ATOM   5592 C CB    . THR C 3 228 ? 114.429 137.848 73.810  1.00 40.82  ? 223 THR B CB    1 
ATOM   5593 O OG1   . THR C 3 228 ? 113.698 138.487 72.757  1.00 40.82  ? 223 THR B OG1   1 
ATOM   5594 C CG2   . THR C 3 228 ? 115.769 137.363 73.275  1.00 40.82  ? 223 THR B CG2   1 
ATOM   5595 N N     . GLY C 3 229 ? 112.210 138.298 75.524  1.00 37.43  ? 224 GLY B N     1 
ATOM   5596 C CA    . GLY C 3 229 ? 110.990 138.734 76.172  1.00 37.43  ? 224 GLY B CA    1 
ATOM   5597 C C     . GLY C 3 229 ? 110.939 138.376 77.636  1.00 37.43  ? 224 GLY B C     1 
ATOM   5598 O O     . GLY C 3 229 ? 109.935 137.832 78.102  1.00 37.43  ? 224 GLY B O     1 
ATOM   5599 N N     . HIS C 3 230 ? 112.005 138.661 78.376  1.00 27.96  ? 225 HIS B N     1 
ATOM   5600 C CA    . HIS C 3 230 ? 112.173 138.178 79.737  1.00 27.96  ? 225 HIS B CA    1 
ATOM   5601 C C     . HIS C 3 230 ? 112.927 139.221 80.550  1.00 27.96  ? 225 HIS B C     1 
ATOM   5602 O O     . HIS C 3 230 ? 113.700 140.007 79.992  1.00 27.96  ? 225 HIS B O     1 
ATOM   5603 C CB    . HIS C 3 230 ? 112.926 136.851 79.730  1.00 27.96  ? 225 HIS B CB    1 
ATOM   5604 C CG    . HIS C 3 230 ? 112.786 136.076 80.996  1.00 27.96  ? 225 HIS B CG    1 
ATOM   5605 N ND1   . HIS C 3 230 ? 113.396 136.456 82.170  1.00 27.96  ? 225 HIS B ND1   1 
ATOM   5606 C CD2   . HIS C 3 230 ? 112.102 134.942 81.273  1.00 27.96  ? 225 HIS B CD2   1 
ATOM   5607 C CE1   . HIS C 3 230 ? 113.091 135.591 83.119  1.00 27.96  ? 225 HIS B CE1   1 
ATOM   5608 N NE2   . HIS C 3 230 ? 112.310 134.660 82.600  1.00 27.96  ? 225 HIS B NE2   1 
ATOM   5609 N N     . GLU C 3 231 ? 112.707 139.224 81.865  1.00 26.66  ? 226 GLU B N     1 
ATOM   5610 C CA    . GLU C 3 231 ? 113.311 140.231 82.730  1.00 26.66  ? 226 GLU B CA    1 
ATOM   5611 C C     . GLU C 3 231 ? 114.555 139.734 83.453  1.00 26.66  ? 226 GLU B C     1 
ATOM   5612 O O     . GLU C 3 231 ? 115.562 140.450 83.492  1.00 26.66  ? 226 GLU B O     1 
ATOM   5613 C CB    . GLU C 3 231 ? 112.293 140.715 83.766  1.00 26.66  ? 226 GLU B CB    1 
ATOM   5614 C CG    . GLU C 3 231 ? 111.121 141.470 83.170  1.00 26.66  ? 226 GLU B CG    1 
ATOM   5615 C CD    . GLU C 3 231 ? 111.537 142.789 82.552  1.00 26.66  ? 226 GLU B CD    1 
ATOM   5616 O OE1   . GLU C 3 231 ? 112.500 143.404 83.055  1.00 26.66  ? 226 GLU B OE1   1 
ATOM   5617 O OE2   . GLU C 3 231 ? 110.901 143.212 81.563  1.00 26.66  ? 226 GLU B OE2   1 
ATOM   5618 N N     . SER C 3 232 ? 114.516 138.535 84.020  1.00 22.70  ? 227 SER B N     1 
ATOM   5619 C CA    . SER C 3 232 ? 115.601 138.004 84.834  1.00 22.70  ? 227 SER B CA    1 
ATOM   5620 C C     . SER C 3 232 ? 116.179 136.752 84.182  1.00 22.70  ? 227 SER B C     1 
ATOM   5621 O O     . SER C 3 232 ? 115.839 136.391 83.053  1.00 22.70  ? 227 SER B O     1 
ATOM   5622 C CB    . SER C 3 232 ? 115.117 137.699 86.253  1.00 22.70  ? 227 SER B CB    1 
ATOM   5623 O OG    . SER C 3 232 ? 116.210 137.454 87.118  1.00 22.70  ? 227 SER B OG    1 
ATOM   5624 N N     . ASP C 3 233 ? 117.071 136.092 84.913  1.00 21.51  ? 228 ASP B N     1 
ATOM   5625 C CA    . ASP C 3 233 ? 117.730 134.900 84.401  1.00 21.51  ? 228 ASP B CA    1 
ATOM   5626 C C     . ASP C 3 233 ? 116.766 133.721 84.350  1.00 21.51  ? 228 ASP B C     1 
ATOM   5627 O O     . ASP C 3 233 ? 115.700 133.729 84.970  1.00 21.51  ? 228 ASP B O     1 
ATOM   5628 C CB    . ASP C 3 233 ? 118.934 134.543 85.271  1.00 21.51  ? 228 ASP B CB    1 
ATOM   5629 C CG    . ASP C 3 233 ? 118.583 134.435 86.736  1.00 21.51  ? 228 ASP B CG    1 
ATOM   5630 O OD1   . ASP C 3 233 ? 118.522 135.484 87.411  1.00 21.51  ? 228 ASP B OD1   1 
ATOM   5631 O OD2   . ASP C 3 233 ? 118.368 133.302 87.212  1.00 21.51  ? 228 ASP B OD2   1 
ATOM   5632 N N     . ILE C 3 234 ? 117.155 132.699 83.593  1.00 18.67  ? 229 ILE B N     1 
ATOM   5633 C CA    . ILE C 3 234 ? 116.393 131.461 83.488  1.00 18.67  ? 229 ILE B CA    1 
ATOM   5634 C C     . ILE C 3 234 ? 117.149 130.366 84.226  1.00 18.67  ? 229 ILE B C     1 
ATOM   5635 O O     . ILE C 3 234 ? 118.333 130.132 83.963  1.00 18.67  ? 229 ILE B O     1 
ATOM   5636 C CB    . ILE C 3 234 ? 116.165 131.075 82.018  1.00 18.67  ? 229 ILE B CB    1 
ATOM   5637 C CG1   . ILE C 3 234 ? 115.661 132.277 81.216  1.00 18.67  ? 229 ILE B CG1   1 
ATOM   5638 C CG2   . ILE C 3 234 ? 115.182 129.917 81.925  1.00 18.67  ? 229 ILE B CG2   1 
ATOM   5639 C CD1   . ILE C 3 234 ? 115.607 132.031 79.732  1.00 18.67  ? 229 ILE B CD1   1 
ATOM   5640 N N     . ASN C 3 235 ? 116.466 129.699 85.157  1.00 17.26  ? 230 ASN B N     1 
ATOM   5641 C CA    . ASN C 3 235 ? 117.063 128.637 85.952  1.00 17.26  ? 230 ASN B CA    1 
ATOM   5642 C C     . ASN C 3 235 ? 116.550 127.250 85.596  1.00 17.26  ? 230 ASN B C     1 
ATOM   5643 O O     . ASN C 3 235 ? 117.100 126.261 86.092  1.00 17.26  ? 230 ASN B O     1 
ATOM   5644 C CB    . ASN C 3 235 ? 116.811 128.892 87.445  1.00 17.26  ? 230 ASN B CB    1 
ATOM   5645 C CG    . ASN C 3 235 ? 117.121 130.315 87.852  1.00 17.26  ? 230 ASN B CG    1 
ATOM   5646 O OD1   . ASN C 3 235 ? 118.261 130.766 87.752  1.00 17.26  ? 230 ASN B OD1   1 
ATOM   5647 N ND2   . ASN C 3 235 ? 116.106 131.034 88.314  1.00 17.26  ? 230 ASN B ND2   1 
ATOM   5648 N N     . ALA C 3 236 ? 115.519 127.145 84.760  1.00 14.62  ? 231 ALA B N     1 
ATOM   5649 C CA    . ALA C 3 236 ? 114.924 125.858 84.437  1.00 14.62  ? 231 ALA B CA    1 
ATOM   5650 C C     . ALA C 3 236 ? 114.300 125.922 83.052  1.00 14.62  ? 231 ALA B C     1 
ATOM   5651 O O     . ALA C 3 236 ? 113.729 126.946 82.670  1.00 14.62  ? 231 ALA B O     1 
ATOM   5652 C CB    . ALA C 3 236 ? 113.870 125.462 85.475  1.00 14.62  ? 231 ALA B CB    1 
ATOM   5653 N N     . ILE C 3 237 ? 114.411 124.822 82.309  1.00 17.18  ? 232 ILE B N     1 
ATOM   5654 C CA    . ILE C 3 237 ? 113.854 124.724 80.965  1.00 17.18  ? 232 ILE B CA    1 
ATOM   5655 C C     . ILE C 3 237 ? 113.496 123.271 80.694  1.00 17.18  ? 232 ILE B C     1 
ATOM   5656 O O     . ILE C 3 237 ? 114.159 122.349 81.178  1.00 17.18  ? 232 ILE B O     1 
ATOM   5657 C CB    . ILE C 3 237 ? 114.833 125.269 79.898  1.00 17.18  ? 232 ILE B CB    1 
ATOM   5658 C CG1   . ILE C 3 237 ? 114.098 125.501 78.576  1.00 17.18  ? 232 ILE B CG1   1 
ATOM   5659 C CG2   . ILE C 3 237 ? 116.002 124.319 79.708  1.00 17.18  ? 232 ILE B CG2   1 
ATOM   5660 C CD1   . ILE C 3 237 ? 114.831 126.413 77.622  1.00 17.18  ? 232 ILE B CD1   1 
ATOM   5661 N N     . CYS C 3 238 ? 112.432 123.071 79.919  1.00 17.88  ? 233 CYS B N     1 
ATOM   5662 C CA    . CYS C 3 238 ? 111.962 121.734 79.588  1.00 17.88  ? 233 CYS B CA    1 
ATOM   5663 C C     . CYS C 3 238 ? 111.147 121.796 78.304  1.00 17.88  ? 233 CYS B C     1 
ATOM   5664 O O     . CYS C 3 238 ? 110.484 122.795 78.017  1.00 17.88  ? 233 CYS B O     1 
ATOM   5665 C CB    . CYS C 3 238 ? 111.125 121.140 80.729  1.00 17.88  ? 233 CYS B CB    1 
ATOM   5666 S SG    . CYS C 3 238 ? 110.550 119.450 80.443  1.00 17.88  ? 233 CYS B SG    1 
ATOM   5667 N N     . PHE C 3 239 ? 111.204 120.713 77.531  1.00 19.23  ? 234 PHE B N     1 
ATOM   5668 C CA    . PHE C 3 239 ? 110.420 120.578 76.310  1.00 19.23  ? 234 PHE B CA    1 
ATOM   5669 C C     . PHE C 3 239 ? 109.005 120.108 76.603  1.00 19.23  ? 234 PHE B C     1 
ATOM   5670 O O     . PHE C 3 239 ? 108.763 119.376 77.567  1.00 19.23  ? 234 PHE B O     1 
ATOM   5671 C CB    . PHE C 3 239 ? 111.048 119.588 75.324  1.00 19.23  ? 234 PHE B CB    1 
ATOM   5672 C CG    . PHE C 3 239 ? 112.119 120.173 74.453  1.00 19.23  ? 234 PHE B CG    1 
ATOM   5673 C CD1   . PHE C 3 239 ? 111.776 120.893 73.322  1.00 19.23  ? 234 PHE B CD1   1 
ATOM   5674 C CD2   . PHE C 3 239 ? 113.456 119.956 74.720  1.00 19.23  ? 234 PHE B CD2   1 
ATOM   5675 C CE1   . PHE C 3 239 ? 112.745 121.419 72.500  1.00 19.23  ? 234 PHE B CE1   1 
ATOM   5676 C CE2   . PHE C 3 239 ? 114.429 120.478 73.894  1.00 19.23  ? 234 PHE B CE2   1 
ATOM   5677 C CZ    . PHE C 3 239 ? 114.073 121.208 72.785  1.00 19.23  ? 234 PHE B CZ    1 
ATOM   5678 N N     . PHE C 3 240 ? 108.076 120.536 75.755  1.00 28.43  ? 235 PHE B N     1 
ATOM   5679 C CA    . PHE C 3 240 ? 106.800 119.859 75.640  1.00 28.43  ? 235 PHE B CA    1 
ATOM   5680 C C     . PHE C 3 240 ? 107.049 118.429 75.161  1.00 28.43  ? 235 PHE B C     1 
ATOM   5681 O O     . PHE C 3 240 ? 108.024 118.172 74.450  1.00 28.43  ? 235 PHE B O     1 
ATOM   5682 C CB    . PHE C 3 240 ? 105.899 120.606 74.656  1.00 28.43  ? 235 PHE B CB    1 
ATOM   5683 C CG    . PHE C 3 240 ? 104.435 120.364 74.860  1.00 28.43  ? 235 PHE B CG    1 
ATOM   5684 C CD1   . PHE C 3 240 ? 103.823 120.693 76.054  1.00 28.43  ? 235 PHE B CD1   1 
ATOM   5685 C CD2   . PHE C 3 240 ? 103.668 119.806 73.853  1.00 28.43  ? 235 PHE B CD2   1 
ATOM   5686 C CE1   . PHE C 3 240 ? 102.478 120.472 76.238  1.00 28.43  ? 235 PHE B CE1   1 
ATOM   5687 C CE2   . PHE C 3 240 ? 102.321 119.581 74.033  1.00 28.43  ? 235 PHE B CE2   1 
ATOM   5688 C CZ    . PHE C 3 240 ? 101.725 119.914 75.226  1.00 28.43  ? 235 PHE B CZ    1 
ATOM   5689 N N     . PRO C 3 241 ? 106.193 117.471 75.534  1.00 28.67  ? 236 PRO B N     1 
ATOM   5690 C CA    . PRO C 3 241 ? 106.513 116.067 75.239  1.00 28.67  ? 236 PRO B CA    1 
ATOM   5691 C C     . PRO C 3 241 ? 106.689 115.786 73.754  1.00 28.67  ? 236 PRO B C     1 
ATOM   5692 O O     . PRO C 3 241 ? 107.328 114.795 73.387  1.00 28.67  ? 236 PRO B O     1 
ATOM   5693 C CB    . PRO C 3 241 ? 105.319 115.299 75.820  1.00 28.67  ? 236 PRO B CB    1 
ATOM   5694 C CG    . PRO C 3 241 ? 104.675 116.230 76.779  1.00 28.67  ? 236 PRO B CG    1 
ATOM   5695 C CD    . PRO C 3 241 ? 104.911 117.600 76.249  1.00 28.67  ? 236 PRO B CD    1 
ATOM   5696 N N     . ASN C 3 242 ? 106.138 116.636 72.890  1.00 32.36  ? 237 ASN B N     1 
ATOM   5697 C CA    . ASN C 3 242 ? 106.298 116.473 71.450  1.00 32.36  ? 237 ASN B CA    1 
ATOM   5698 C C     . ASN C 3 242 ? 107.511 117.210 70.898  1.00 32.36  ? 237 ASN B C     1 
ATOM   5699 O O     . ASN C 3 242 ? 107.751 117.154 69.688  1.00 32.36  ? 237 ASN B O     1 
ATOM   5700 C CB    . ASN C 3 242 ? 105.044 116.954 70.714  1.00 32.36  ? 237 ASN B CB    1 
ATOM   5701 C CG    . ASN C 3 242 ? 104.790 118.436 70.894  1.00 32.36  ? 237 ASN B CG    1 
ATOM   5702 O OD1   . ASN C 3 242 ? 105.606 119.154 71.470  1.00 32.36  ? 237 ASN B OD1   1 
ATOM   5703 N ND2   . ASN C 3 242 ? 103.658 118.907 70.384  1.00 32.36  ? 237 ASN B ND2   1 
ATOM   5704 N N     . GLY C 3 243 ? 108.274 117.894 71.743  1.00 28.59  ? 238 GLY B N     1 
ATOM   5705 C CA    . GLY C 3 243 ? 109.434 118.628 71.264  1.00 28.59  ? 238 GLY B CA    1 
ATOM   5706 C C     . GLY C 3 243 ? 109.083 119.764 70.329  1.00 28.59  ? 238 GLY B C     1 
ATOM   5707 O O     . GLY C 3 243 ? 109.919 120.178 69.516  1.00 28.59  ? 238 GLY B O     1 
ATOM   5708 N N     . ASN C 3 244 ? 107.859 120.284 70.427  1.00 34.60  ? 239 ASN B N     1 
ATOM   5709 C CA    . ASN C 3 244 ? 107.415 121.397 69.602  1.00 34.60  ? 239 ASN B CA    1 
ATOM   5710 C C     . ASN C 3 244 ? 107.272 122.693 70.386  1.00 34.60  ? 239 ASN B C     1 
ATOM   5711 O O     . ASN C 3 244 ? 106.758 123.675 69.841  1.00 34.60  ? 239 ASN B O     1 
ATOM   5712 C CB    . ASN C 3 244 ? 106.077 121.064 68.927  1.00 34.60  ? 239 ASN B CB    1 
ATOM   5713 C CG    . ASN C 3 244 ? 106.236 120.127 67.748  1.00 34.60  ? 239 ASN B CG    1 
ATOM   5714 O OD1   . ASN C 3 244 ? 107.350 119.847 67.307  1.00 34.60  ? 239 ASN B OD1   1 
ATOM   5715 N ND2   . ASN C 3 244 ? 105.117 119.632 67.232  1.00 34.60  ? 239 ASN B ND2   1 
ATOM   5716 N N     . ALA C 3 245 ? 107.710 122.725 71.638  1.00 29.74  ? 240 ALA B N     1 
ATOM   5717 C CA    . ALA C 3 245 ? 107.629 123.914 72.479  1.00 29.74  ? 240 ALA B CA    1 
ATOM   5718 C C     . ALA C 3 245 ? 108.487 123.654 73.709  1.00 29.74  ? 240 ALA B C     1 
ATOM   5719 O O     . ALA C 3 245 ? 109.066 122.575 73.866  1.00 29.74  ? 240 ALA B O     1 
ATOM   5720 C CB    . ALA C 3 245 ? 106.182 124.236 72.857  1.00 29.74  ? 240 ALA B CB    1 
ATOM   5721 N N     . PHE C 3 246 ? 108.573 124.653 74.582  1.00 24.31  ? 241 PHE B N     1 
ATOM   5722 C CA    . PHE C 3 246 ? 109.328 124.470 75.814  1.00 24.31  ? 241 PHE B CA    1 
ATOM   5723 C C     . PHE C 3 246 ? 108.949 125.553 76.811  1.00 24.31  ? 241 PHE B C     1 
ATOM   5724 O O     . PHE C 3 246 ? 108.621 126.679 76.432  1.00 24.31  ? 241 PHE B O     1 
ATOM   5725 C CB    . PHE C 3 246 ? 110.840 124.492 75.563  1.00 24.31  ? 241 PHE B CB    1 
ATOM   5726 C CG    . PHE C 3 246 ? 111.318 125.712 74.829  1.00 24.31  ? 241 PHE B CG    1 
ATOM   5727 C CD1   . PHE C 3 246 ? 111.007 125.908 73.495  1.00 24.31  ? 241 PHE B CD1   1 
ATOM   5728 C CD2   . PHE C 3 246 ? 112.080 126.665 75.480  1.00 24.31  ? 241 PHE B CD2   1 
ATOM   5729 C CE1   . PHE C 3 246 ? 111.447 127.028 72.831  1.00 24.31  ? 241 PHE B CE1   1 
ATOM   5730 C CE2   . PHE C 3 246 ? 112.522 127.786 74.818  1.00 24.31  ? 241 PHE B CE2   1 
ATOM   5731 C CZ    . PHE C 3 246 ? 112.205 127.967 73.493  1.00 24.31  ? 241 PHE B CZ    1 
ATOM   5732 N N     . ALA C 3 247 ? 109.026 125.204 78.092  1.00 18.41  ? 242 ALA B N     1 
ATOM   5733 C CA    . ALA C 3 247 ? 108.706 126.113 79.181  1.00 18.41  ? 242 ALA B CA    1 
ATOM   5734 C C     . ALA C 3 247 ? 109.967 126.435 79.969  1.00 18.41  ? 242 ALA B C     1 
ATOM   5735 O O     . ALA C 3 247 ? 110.826 125.571 80.168  1.00 18.41  ? 242 ALA B O     1 
ATOM   5736 C CB    . ALA C 3 247 ? 107.647 125.517 80.112  1.00 18.41  ? 242 ALA B CB    1 
ATOM   5737 N N     . THR C 3 248 ? 110.065 127.683 80.411  1.00 19.99  ? 243 THR B N     1 
ATOM   5738 C CA    . THR C 3 248 ? 111.206 128.193 81.151  1.00 19.99  ? 243 THR B CA    1 
ATOM   5739 C C     . THR C 3 248 ? 110.742 128.766 82.482  1.00 19.99  ? 243 THR B C     1 
ATOM   5740 O O     . THR C 3 248 ? 109.663 129.353 82.584  1.00 19.99  ? 243 THR B O     1 
ATOM   5741 C CB    . THR C 3 248 ? 111.943 129.283 80.361  1.00 19.99  ? 243 THR B CB    1 
ATOM   5742 O OG1   . THR C 3 248 ? 111.058 130.385 80.127  1.00 19.99  ? 243 THR B OG1   1 
ATOM   5743 C CG2   . THR C 3 248 ? 112.435 128.749 79.034  1.00 19.99  ? 243 THR B CG2   1 
ATOM   5744 N N     . GLY C 3 249 ? 111.584 128.599 83.499  1.00 16.64  ? 244 GLY B N     1 
ATOM   5745 C CA    . GLY C 3 249 ? 111.342 129.165 84.811  1.00 16.64  ? 244 GLY B CA    1 
ATOM   5746 C C     . GLY C 3 249 ? 112.469 130.096 85.205  1.00 16.64  ? 244 GLY B C     1 
ATOM   5747 O O     . GLY C 3 249 ? 113.613 129.882 84.798  1.00 16.64  ? 244 GLY B O     1 
ATOM   5748 N N     . SER C 3 250 ? 112.175 131.123 85.994  1.00 19.24  ? 245 SER B N     1 
ATOM   5749 C CA    . SER C 3 250 ? 113.111 132.216 86.207  1.00 19.24  ? 245 SER B CA    1 
ATOM   5750 C C     . SER C 3 250 ? 113.009 132.784 87.616  1.00 19.24  ? 245 SER B C     1 
ATOM   5751 O O     . SER C 3 250 ? 112.058 132.528 88.358  1.00 19.24  ? 245 SER B O     1 
ATOM   5752 C CB    . SER C 3 250 ? 112.855 133.327 85.191  1.00 19.24  ? 245 SER B CB    1 
ATOM   5753 O OG    . SER C 3 250 ? 113.148 132.886 83.878  1.00 19.24  ? 245 SER B OG    1 
ATOM   5754 N N     . ASP C 3 251 ? 114.020 133.580 87.967  1.00 17.97  ? 246 ASP B N     1 
ATOM   5755 C CA    . ASP C 3 251 ? 113.999 134.393 89.176  1.00 17.97  ? 246 ASP B CA    1 
ATOM   5756 C C     . ASP C 3 251 ? 112.982 135.521 89.097  1.00 17.97  ? 246 ASP B C     1 
ATOM   5757 O O     . ASP C 3 251 ? 112.701 136.156 90.119  1.00 17.97  ? 246 ASP B O     1 
ATOM   5758 C CB    . ASP C 3 251 ? 115.389 134.974 89.442  1.00 17.97  ? 246 ASP B CB    1 
ATOM   5759 C CG    . ASP C 3 251 ? 116.310 133.990 90.134  1.00 17.97  ? 246 ASP B CG    1 
ATOM   5760 O OD1   . ASP C 3 251 ? 115.814 132.967 90.651  1.00 17.97  ? 246 ASP B OD1   1 
ATOM   5761 O OD2   . ASP C 3 251 ? 117.533 134.240 90.163  1.00 17.97  ? 246 ASP B OD2   1 
ATOM   5762 N N     . ASP C 3 252 ? 112.426 135.777 87.913  1.00 20.50  ? 247 ASP B N     1 
ATOM   5763 C CA    . ASP C 3 252 ? 111.364 136.757 87.742  1.00 20.50  ? 247 ASP B CA    1 
ATOM   5764 C C     . ASP C 3 252 ? 110.117 136.396 88.539  1.00 20.50  ? 247 ASP B C     1 
ATOM   5765 O O     . ASP C 3 252 ? 109.280 137.272 88.776  1.00 20.50  ? 247 ASP B O     1 
ATOM   5766 C CB    . ASP C 3 252 ? 111.022 136.866 86.251  1.00 20.50  ? 247 ASP B CB    1 
ATOM   5767 C CG    . ASP C 3 252 ? 110.142 138.064 85.921  1.00 20.50  ? 247 ASP B CG    1 
ATOM   5768 O OD1   . ASP C 3 252 ? 109.383 138.537 86.790  1.00 20.50  ? 247 ASP B OD1   1 
ATOM   5769 O OD2   . ASP C 3 252 ? 110.199 138.525 84.763  1.00 20.50  ? 247 ASP B OD2   1 
ATOM   5770 N N     . ALA C 3 253 ? 109.990 135.142 88.974  1.00 17.84  ? 248 ALA B N     1 
ATOM   5771 C CA    . ALA C 3 253 ? 108.781 134.590 89.575  1.00 17.84  ? 248 ALA B CA    1 
ATOM   5772 C C     . ALA C 3 253 ? 107.726 134.285 88.524  1.00 17.84  ? 248 ALA B C     1 
ATOM   5773 O O     . ALA C 3 253 ? 106.532 134.229 88.835  1.00 17.84  ? 248 ALA B O     1 
ATOM   5774 C CB    . ALA C 3 253 ? 108.192 135.520 90.641  1.00 17.84  ? 248 ALA B CB    1 
ATOM   5775 N N     . THR C 3 254 ? 108.149 134.086 87.279  1.00 19.57  ? 249 THR B N     1 
ATOM   5776 C CA    . THR C 3 254 ? 107.259 133.781 86.173  1.00 19.57  ? 249 THR B CA    1 
ATOM   5777 C C     . THR C 3 254 ? 107.802 132.584 85.408  1.00 19.57  ? 249 THR B C     1 
ATOM   5778 O O     . THR C 3 254 ? 109.012 132.344 85.375  1.00 19.57  ? 249 THR B O     1 
ATOM   5779 C CB    . THR C 3 254 ? 107.114 134.981 85.225  1.00 19.57  ? 249 THR B CB    1 
ATOM   5780 O OG1   . THR C 3 254 ? 106.619 136.111 85.953  1.00 19.57  ? 249 THR B OG1   1 
ATOM   5781 C CG2   . THR C 3 254 ? 106.166 134.659 84.079  1.00 19.57  ? 249 THR B CG2   1 
ATOM   5782 N N     . CYS C 3 255 ? 106.892 131.826 84.807  1.00 20.22  ? 250 CYS B N     1 
ATOM   5783 C CA    . CYS C 3 255 ? 107.240 130.749 83.895  1.00 20.22  ? 250 CYS B CA    1 
ATOM   5784 C C     . CYS C 3 255 ? 106.624 131.047 82.537  1.00 20.22  ? 250 CYS B C     1 
ATOM   5785 O O     . CYS C 3 255 ? 105.472 131.482 82.448  1.00 20.22  ? 250 CYS B O     1 
ATOM   5786 C CB    . CYS C 3 255 ? 106.765 129.388 84.420  1.00 20.22  ? 250 CYS B CB    1 
ATOM   5787 S SG    . CYS C 3 255 ? 107.917 128.592 85.561  1.00 20.22  ? 250 CYS B SG    1 
ATOM   5788 N N     . ARG C 3 256 ? 107.404 130.825 81.484  1.00 26.53  ? 251 ARG B N     1 
ATOM   5789 C CA    . ARG C 3 256 ? 107.048 131.252 80.135  1.00 26.53  ? 251 ARG B CA    1 
ATOM   5790 C C     . ARG C 3 256 ? 107.106 130.061 79.191  1.00 26.53  ? 251 ARG B C     1 
ATOM   5791 O O     . ARG C 3 256 ? 108.099 129.330 79.171  1.00 26.53  ? 251 ARG B O     1 
ATOM   5792 C CB    . ARG C 3 256 ? 107.989 132.360 79.656  1.00 26.53  ? 251 ARG B CB    1 
ATOM   5793 C CG    . ARG C 3 256 ? 107.929 133.615 80.507  1.00 26.53  ? 251 ARG B CG    1 
ATOM   5794 C CD    . ARG C 3 256 ? 108.818 134.717 79.961  1.00 26.53  ? 251 ARG B CD    1 
ATOM   5795 N NE    . ARG C 3 256 ? 108.917 135.836 80.891  1.00 26.53  ? 251 ARG B NE    1 
ATOM   5796 C CZ    . ARG C 3 256 ? 108.216 136.959 80.804  1.00 26.53  ? 251 ARG B CZ    1 
ATOM   5797 N NH1   . ARG C 3 256 ? 107.328 137.151 79.843  1.00 26.53  ? 251 ARG B NH1   1 
ATOM   5798 N NH2   . ARG C 3 256 ? 108.407 137.913 81.711  1.00 26.53  ? 251 ARG B NH2   1 
ATOM   5799 N N     . LEU C 3 257 ? 106.052 129.880 78.402  1.00 30.37  ? 252 LEU B N     1 
ATOM   5800 C CA    . LEU C 3 257 ? 105.999 128.826 77.399  1.00 30.37  ? 252 LEU B CA    1 
ATOM   5801 C C     . LEU C 3 257 ? 106.204 129.437 76.019  1.00 30.37  ? 252 LEU B C     1 
ATOM   5802 O O     . LEU C 3 257 ? 105.436 130.317 75.604  1.00 30.37  ? 252 LEU B O     1 
ATOM   5803 C CB    . LEU C 3 257 ? 104.662 128.086 77.467  1.00 30.37  ? 252 LEU B CB    1 
ATOM   5804 C CG    . LEU C 3 257 ? 104.431 126.954 76.460  1.00 30.37  ? 252 LEU B CG    1 
ATOM   5805 C CD1   . LEU C 3 257 ? 103.491 125.914 77.043  1.00 30.37  ? 252 LEU B CD1   1 
ATOM   5806 C CD2   . LEU C 3 257 ? 103.875 127.471 75.144  1.00 30.37  ? 252 LEU B CD2   1 
ATOM   5807 N N     . PHE C 3 258 ? 107.243 128.963 75.323  1.00 30.28  ? 253 PHE B N     1 
ATOM   5808 C CA    . PHE C 3 258 ? 107.612 129.396 73.984  1.00 30.28  ? 253 PHE B CA    1 
ATOM   5809 C C     . PHE C 3 258 ? 107.401 128.260 72.992  1.00 30.28  ? 253 PHE B C     1 
ATOM   5810 O O     . PHE C 3 258 ? 107.447 127.079 73.354  1.00 30.28  ? 253 PHE B O     1 
ATOM   5811 C CB    . PHE C 3 258 ? 109.089 129.820 73.903  1.00 30.28  ? 253 PHE B CB    1 
ATOM   5812 C CG    . PHE C 3 258 ? 109.493 130.857 74.907  1.00 30.28  ? 253 PHE B CG    1 
ATOM   5813 C CD1   . PHE C 3 258 ? 109.927 130.485 76.167  1.00 30.28  ? 253 PHE B CD1   1 
ATOM   5814 C CD2   . PHE C 3 258 ? 109.465 132.201 74.584  1.00 30.28  ? 253 PHE B CD2   1 
ATOM   5815 C CE1   . PHE C 3 258 ? 110.308 131.435 77.090  1.00 30.28  ? 253 PHE B CE1   1 
ATOM   5816 C CE2   . PHE C 3 258 ? 109.845 133.153 75.503  1.00 30.28  ? 253 PHE B CE2   1 
ATOM   5817 C CZ    . PHE C 3 258 ? 110.267 132.771 76.757  1.00 30.28  ? 253 PHE B CZ    1 
ATOM   5818 N N     . ASP C 3 259 ? 107.198 128.634 71.732  1.00 41.35  ? 254 ASP B N     1 
ATOM   5819 C CA    . ASP C 3 259 ? 107.168 127.708 70.610  1.00 41.35  ? 254 ASP B CA    1 
ATOM   5820 C C     . ASP C 3 259 ? 108.363 127.974 69.703  1.00 41.35  ? 254 ASP B C     1 
ATOM   5821 O O     . ASP C 3 259 ? 108.713 129.127 69.435  1.00 41.35  ? 254 ASP B O     1 
ATOM   5822 C CB    . ASP C 3 259 ? 105.871 127.850 69.810  1.00 41.35  ? 254 ASP B CB    1 
ATOM   5823 C CG    . ASP C 3 259 ? 105.693 126.749 68.785  1.00 41.35  ? 254 ASP B CG    1 
ATOM   5824 O OD1   . ASP C 3 259 ? 105.310 125.628 69.178  1.00 41.35  ? 254 ASP B OD1   1 
ATOM   5825 O OD2   . ASP C 3 259 ? 105.934 127.003 67.586  1.00 41.35  ? 254 ASP B OD2   1 
ATOM   5826 N N     . LEU C 3 260 ? 108.989 126.898 69.226  1.00 37.56  ? 255 LEU B N     1 
ATOM   5827 C CA    . LEU C 3 260 ? 110.189 127.004 68.408  1.00 37.56  ? 255 LEU B CA    1 
ATOM   5828 C C     . LEU C 3 260 ? 109.870 127.251 66.938  1.00 37.56  ? 255 LEU B C     1 
ATOM   5829 O O     . LEU C 3 260 ? 110.790 127.417 66.130  1.00 37.56  ? 255 LEU B O     1 
ATOM   5830 C CB    . LEU C 3 260 ? 111.049 125.746 68.551  1.00 37.56  ? 255 LEU B CB    1 
ATOM   5831 C CG    . LEU C 3 260 ? 110.640 124.500 67.756  1.00 37.56  ? 255 LEU B CG    1 
ATOM   5832 C CD1   . LEU C 3 260 ? 111.770 123.479 67.759  1.00 37.56  ? 255 LEU B CD1   1 
ATOM   5833 C CD2   . LEU C 3 260 ? 109.366 123.887 68.293  1.00 37.56  ? 255 LEU B CD2   1 
ATOM   5834 N N     . ARG C 3 261 ? 108.590 127.282 66.575  1.00 49.67  ? 256 ARG B N     1 
ATOM   5835 C CA    . ARG C 3 261 ? 108.181 127.546 65.200  1.00 49.67  ? 256 ARG B CA    1 
ATOM   5836 C C     . ARG C 3 261 ? 107.665 128.969 65.039  1.00 49.67  ? 256 ARG B C     1 
ATOM   5837 O O     . ARG C 3 261 ? 108.048 129.653 64.084  1.00 49.67  ? 256 ARG B O     1 
ATOM   5838 C CB    . ARG C 3 261 ? 107.124 126.523 64.763  1.00 49.67  ? 256 ARG B CB    1 
ATOM   5839 C CG    . ARG C 3 261 ? 107.379 125.119 65.292  1.00 49.67  ? 256 ARG B CG    1 
ATOM   5840 C CD    . ARG C 3 261 ? 106.478 124.088 64.633  1.00 49.67  ? 256 ARG B CD    1 
ATOM   5841 N NE    . ARG C 3 261 ? 105.065 124.425 64.749  1.00 49.67  ? 256 ARG B NE    1 
ATOM   5842 C CZ    . ARG C 3 261 ? 104.076 123.679 64.276  1.00 49.67  ? 256 ARG B CZ    1 
ATOM   5843 N NH1   . ARG C 3 261 ? 104.309 122.539 63.646  1.00 49.67  ? 256 ARG B NH1   1 
ATOM   5844 N NH2   . ARG C 3 261 ? 102.821 124.088 64.438  1.00 49.67  ? 256 ARG B NH2   1 
ATOM   5845 N N     . ALA C 3 262 ? 106.807 129.438 65.947  1.00 54.31  ? 257 ALA B N     1 
ATOM   5846 C CA    . ALA C 3 262 ? 106.357 130.823 65.889  1.00 54.31  ? 257 ALA B CA    1 
ATOM   5847 C C     . ALA C 3 262 ? 107.479 131.794 66.226  1.00 54.31  ? 257 ALA B C     1 
ATOM   5848 O O     . ALA C 3 262 ? 107.420 132.968 65.843  1.00 54.31  ? 257 ALA B O     1 
ATOM   5849 C CB    . ALA C 3 262 ? 105.179 131.031 66.841  1.00 54.31  ? 257 ALA B CB    1 
ATOM   5850 N N     . ASP C 3 263 ? 108.502 131.331 66.943  1.00 56.07  ? 258 ASP B N     1 
ATOM   5851 C CA    . ASP C 3 263 ? 109.636 132.127 67.397  1.00 56.07  ? 258 ASP B CA    1 
ATOM   5852 C C     . ASP C 3 263 ? 109.229 133.184 68.413  1.00 56.07  ? 258 ASP B C     1 
ATOM   5853 O O     . ASP C 3 263 ? 110.048 134.050 68.745  1.00 56.07  ? 258 ASP B O     1 
ATOM   5854 C CB    . ASP C 3 263 ? 110.367 132.816 66.235  1.00 56.07  ? 258 ASP B CB    1 
ATOM   5855 C CG    . ASP C 3 263 ? 110.923 131.829 65.230  1.00 56.07  ? 258 ASP B CG    1 
ATOM   5856 O OD1   . ASP C 3 263 ? 110.675 130.615 65.388  1.00 56.07  ? 258 ASP B OD1   1 
ATOM   5857 O OD2   . ASP C 3 263 ? 111.611 132.265 64.283  1.00 56.07  ? 258 ASP B OD2   1 
ATOM   5858 N N     . GLN C 3 264 ? 108.000 133.146 68.921  1.00 55.45  ? 259 GLN B N     1 
ATOM   5859 C CA    . GLN C 3 264 ? 107.501 134.127 69.870  1.00 55.45  ? 259 GLN B CA    1 
ATOM   5860 C C     . GLN C 3 264 ? 107.017 133.424 71.130  1.00 55.45  ? 259 GLN B C     1 
ATOM   5861 O O     . GLN C 3 264 ? 106.598 132.263 71.100  1.00 55.45  ? 259 GLN B O     1 
ATOM   5862 C CB    . GLN C 3 264 ? 106.354 134.950 69.268  1.00 55.45  ? 259 GLN B CB    1 
ATOM   5863 C CG    . GLN C 3 264 ? 105.906 136.117 70.134  1.00 55.45  ? 259 GLN B CG    1 
ATOM   5864 C CD    . GLN C 3 264 ? 104.824 136.947 69.476  1.00 55.45  ? 259 GLN B CD    1 
ATOM   5865 O OE1   . GLN C 3 264 ? 104.346 136.617 68.390  1.00 55.45  ? 259 GLN B OE1   1 
ATOM   5866 N NE2   . GLN C 3 264 ? 104.431 138.033 70.130  1.00 55.45  ? 259 GLN B NE2   1 
ATOM   5867 N N     . GLU C 3 265 ? 107.083 134.143 72.246  1.00 39.07  ? 260 GLU B N     1 
ATOM   5868 C CA    . GLU C 3 265 ? 106.561 133.620 73.499  1.00 39.07  ? 260 GLU B CA    1 
ATOM   5869 C C     . GLU C 3 265 ? 105.061 133.385 73.381  1.00 39.07  ? 260 GLU B C     1 
ATOM   5870 O O     . GLU C 3 265 ? 104.318 134.241 72.893  1.00 39.07  ? 260 GLU B O     1 
ATOM   5871 C CB    . GLU C 3 265 ? 106.856 134.591 74.641  1.00 39.07  ? 260 GLU B CB    1 
ATOM   5872 C CG    . GLU C 3 265 ? 106.485 134.068 76.016  1.00 39.07  ? 260 GLU B CG    1 
ATOM   5873 C CD    . GLU C 3 265 ? 106.587 135.132 77.087  1.00 39.07  ? 260 GLU B CD    1 
ATOM   5874 O OE1   . GLU C 3 265 ? 106.976 136.272 76.759  1.00 39.07  ? 260 GLU B OE1   1 
ATOM   5875 O OE2   . GLU C 3 265 ? 106.276 134.829 78.257  1.00 39.07  ? 260 GLU B OE2   1 
ATOM   5876 N N     . LEU C 3 266 ? 104.615 132.214 73.833  1.00 40.89  ? 261 LEU B N     1 
ATOM   5877 C CA    . LEU C 3 266 ? 103.205 131.861 73.729  1.00 40.89  ? 261 LEU B CA    1 
ATOM   5878 C C     . LEU C 3 266 ? 102.423 132.232 74.981  1.00 40.89  ? 261 LEU B C     1 
ATOM   5879 O O     . LEU C 3 266 ? 101.359 132.851 74.884  1.00 40.89  ? 261 LEU B O     1 
ATOM   5880 C CB    . LEU C 3 266 ? 103.045 130.363 73.456  1.00 40.89  ? 261 LEU B CB    1 
ATOM   5881 C CG    . LEU C 3 266 ? 103.233 129.862 72.025  1.00 40.89  ? 261 LEU B CG    1 
ATOM   5882 C CD1   . LEU C 3 266 ? 103.105 128.348 72.005  1.00 40.89  ? 261 LEU B CD1   1 
ATOM   5883 C CD2   . LEU C 3 266 ? 102.232 130.501 71.075  1.00 40.89  ? 261 LEU B CD2   1 
ATOM   5884 N N     . MET C 3 267 ? 102.921 131.862 76.160  1.00 35.35  ? 262 MET B N     1 
ATOM   5885 C CA    . MET C 3 267 ? 102.118 132.038 77.364  1.00 35.35  ? 262 MET B CA    1 
ATOM   5886 C C     . MET C 3 267 ? 103.001 132.390 78.552  1.00 35.35  ? 262 MET B C     1 
ATOM   5887 O O     . MET C 3 267 ? 104.179 132.035 78.606  1.00 35.35  ? 262 MET B O     1 
ATOM   5888 C CB    . MET C 3 267 ? 101.300 130.777 77.671  1.00 35.35  ? 262 MET B CB    1 
ATOM   5889 C CG    . MET C 3 267 ? 100.542 130.832 78.986  1.00 35.35  ? 262 MET B CG    1 
ATOM   5890 S SD    . MET C 3 267 ? 99.109  129.743 79.004  1.00 35.35  ? 262 MET B SD    1 
ATOM   5891 C CE    . MET C 3 267 ? 97.782  130.921 78.777  1.00 35.35  ? 262 MET B CE    1 
ATOM   5892 N N     . THR C 3 268 ? 102.402 133.092 79.513  1.00 27.88  ? 263 THR B N     1 
ATOM   5893 C CA    . THR C 3 268 ? 103.043 133.451 80.768  1.00 27.88  ? 263 THR B CA    1 
ATOM   5894 C C     . THR C 3 268 ? 102.364 132.722 81.921  1.00 27.88  ? 263 THR B C     1 
ATOM   5895 O O     . THR C 3 268 ? 101.140 132.563 81.942  1.00 27.88  ? 263 THR B O     1 
ATOM   5896 C CB    . THR C 3 268 ? 102.980 134.962 81.013  1.00 27.88  ? 263 THR B CB    1 
ATOM   5897 O OG1   . THR C 3 268 ? 101.612 135.378 81.098  1.00 27.88  ? 263 THR B OG1   1 
ATOM   5898 C CG2   . THR C 3 268 ? 103.669 135.719 79.890  1.00 27.88  ? 263 THR B CG2   1 
ATOM   5899 N N     . TYR C 3 269 ? 103.173 132.280 82.886  1.00 22.52  ? 264 TYR B N     1 
ATOM   5900 C CA    . TYR C 3 269 ? 102.697 131.513 84.036  1.00 22.52  ? 264 TYR B CA    1 
ATOM   5901 C C     . TYR C 3 269 ? 103.144 132.241 85.306  1.00 22.52  ? 264 TYR B C     1 
ATOM   5902 O O     . TYR C 3 269 ? 104.195 131.944 85.877  1.00 22.52  ? 264 TYR B O     1 
ATOM   5903 C CB    . TYR C 3 269 ? 103.231 130.081 83.996  1.00 22.52  ? 264 TYR B CB    1 
ATOM   5904 C CG    . TYR C 3 269 ? 102.727 129.259 82.832  1.00 22.52  ? 264 TYR B CG    1 
ATOM   5905 C CD1   . TYR C 3 269 ? 101.373 129.119 82.588  1.00 22.52  ? 264 TYR B CD1   1 
ATOM   5906 C CD2   . TYR C 3 269 ? 103.615 128.637 81.965  1.00 22.52  ? 264 TYR B CD2   1 
ATOM   5907 C CE1   . TYR C 3 269 ? 100.915 128.372 81.523  1.00 22.52  ? 264 TYR B CE1   1 
ATOM   5908 C CE2   . TYR C 3 269 ? 103.166 127.892 80.897  1.00 22.52  ? 264 TYR B CE2   1 
ATOM   5909 C CZ    . TYR C 3 269 ? 101.815 127.763 80.680  1.00 22.52  ? 264 TYR B CZ    1 
ATOM   5910 O OH    . TYR C 3 269 ? 101.362 127.020 79.617  1.00 22.52  ? 264 TYR B OH    1 
ATOM   5911 N N     . SER C 3 270 ? 102.330 133.196 85.752  1.00 21.25  ? 265 SER B N     1 
ATOM   5912 C CA    . SER C 3 270 ? 102.657 134.023 86.903  1.00 21.25  ? 265 SER B CA    1 
ATOM   5913 C C     . SER C 3 270 ? 101.400 134.325 87.704  1.00 21.25  ? 265 SER B C     1 
ATOM   5914 O O     . SER C 3 270 ? 100.286 134.316 87.174  1.00 21.25  ? 265 SER B O     1 
ATOM   5915 C CB    . SER C 3 270 ? 103.320 135.339 86.477  1.00 21.25  ? 265 SER B CB    1 
ATOM   5916 O OG    . SER C 3 270 ? 103.869 136.015 87.594  1.00 21.25  ? 265 SER B OG    1 
ATOM   5917 N N     . HIS C 3 271 ? 101.595 134.589 88.993  1.00 22.08  ? 266 HIS B N     1 
ATOM   5918 C CA    . HIS C 3 271 ? 100.529 135.006 89.891  1.00 22.08  ? 266 HIS B CA    1 
ATOM   5919 C C     . HIS C 3 271 ? 101.057 136.097 90.811  1.00 22.08  ? 266 HIS B C     1 
ATOM   5920 O O     . HIS C 3 271 ? 102.253 136.138 91.116  1.00 22.08  ? 266 HIS B O     1 
ATOM   5921 C CB    . HIS C 3 271 ? 99.996  133.826 90.709  1.00 22.08  ? 266 HIS B CB    1 
ATOM   5922 C CG    . HIS C 3 271 ? 98.831  134.172 91.581  1.00 22.08  ? 266 HIS B CG    1 
ATOM   5923 N ND1   . HIS C 3 271 ? 97.602  134.535 91.073  1.00 22.08  ? 266 HIS B ND1   1 
ATOM   5924 C CD2   . HIS C 3 271 ? 98.706  134.204 92.929  1.00 22.08  ? 266 HIS B CD2   1 
ATOM   5925 C CE1   . HIS C 3 271 ? 96.772  134.781 92.070  1.00 22.08  ? 266 HIS B CE1   1 
ATOM   5926 N NE2   . HIS C 3 271 ? 97.416  134.588 93.207  1.00 22.08  ? 266 HIS B NE2   1 
ATOM   5927 N N     . ASP C 3 272 ? 100.158 136.980 91.252  1.00 25.93  ? 267 ASP B N     1 
ATOM   5928 C CA    . ASP C 3 272 ? 100.582 138.144 92.023  1.00 25.93  ? 267 ASP B CA    1 
ATOM   5929 C C     . ASP C 3 272 ? 101.202 137.738 93.355  1.00 25.93  ? 267 ASP B C     1 
ATOM   5930 O O     . ASP C 3 272 ? 102.206 138.319 93.783  1.00 25.93  ? 267 ASP B O     1 
ATOM   5931 C CB    . ASP C 3 272 ? 99.394  139.078 92.248  1.00 25.93  ? 267 ASP B CB    1 
ATOM   5932 C CG    . ASP C 3 272 ? 99.819  140.489 92.597  1.00 25.93  ? 267 ASP B CG    1 
ATOM   5933 O OD1   . ASP C 3 272 ? 101.040 140.744 92.667  1.00 25.93  ? 267 ASP B OD1   1 
ATOM   5934 O OD2   . ASP C 3 272 ? 98.932  141.344 92.798  1.00 25.93  ? 267 ASP B OD2   1 
ATOM   5935 N N     . ASN C 3 273 ? 100.618 136.745 94.028  1.00 23.55  ? 268 ASN B N     1 
ATOM   5936 C CA    . ASN C 3 273 ? 101.137 136.323 95.324  1.00 23.55  ? 268 ASN B CA    1 
ATOM   5937 C C     . ASN C 3 273 ? 102.491 135.637 95.212  1.00 23.55  ? 268 ASN B C     1 
ATOM   5938 O O     . ASN C 3 273 ? 103.180 135.486 96.226  1.00 23.55  ? 268 ASN B O     1 
ATOM   5939 C CB    . ASN C 3 273 ? 100.140 135.389 96.011  1.00 23.55  ? 268 ASN B CB    1 
ATOM   5940 C CG    . ASN C 3 273 ? 98.734  135.955 96.038  1.00 23.55  ? 268 ASN B CG    1 
ATOM   5941 O OD1   . ASN C 3 273 ? 97.807  135.374 95.475  1.00 23.55  ? 268 ASN B OD1   1 
ATOM   5942 N ND2   . ASN C 3 273 ? 98.569  137.097 96.696  1.00 23.55  ? 268 ASN B ND2   1 
ATOM   5943 N N     . ILE C 3 274 ? 102.886 135.217 94.015  1.00 18.80  ? 269 ILE B N     1 
ATOM   5944 C CA    . ILE C 3 274 ? 104.181 134.580 93.801  1.00 18.80  ? 269 ILE B CA    1 
ATOM   5945 C C     . ILE C 3 274 ? 105.231 135.677 93.689  1.00 18.80  ? 269 ILE B C     1 
ATOM   5946 O O     . ILE C 3 274 ? 105.167 136.519 92.787  1.00 18.80  ? 269 ILE B O     1 
ATOM   5947 C CB    . ILE C 3 274 ? 104.167 133.696 92.545  1.00 18.80  ? 269 ILE B CB    1 
ATOM   5948 C CG1   . ILE C 3 274 ? 103.053 132.646 92.631  1.00 18.80  ? 269 ILE B CG1   1 
ATOM   5949 C CG2   . ILE C 3 274 ? 105.513 133.015 92.361  1.00 18.80  ? 269 ILE B CG2   1 
ATOM   5950 C CD1   . ILE C 3 274 ? 103.242 131.617 93.728  1.00 18.80  ? 269 ILE B CD1   1 
ATOM   5951 N N     . ILE C 3 275 ? 106.200 135.666 94.602  1.00 19.40  ? 270 ILE B N     1 
ATOM   5952 C CA    . ILE C 3 275 ? 107.200 136.724 94.686  1.00 19.40  ? 270 ILE B CA    1 
ATOM   5953 C C     . ILE C 3 275 ? 108.611 136.231 94.410  1.00 19.40  ? 270 ILE B C     1 
ATOM   5954 O O     . ILE C 3 275 ? 109.499 137.061 94.160  1.00 19.40  ? 270 ILE B O     1 
ATOM   5955 C CB    . ILE C 3 275 ? 107.155 137.428 96.061  1.00 19.40  ? 270 ILE B CB    1 
ATOM   5956 C CG1   . ILE C 3 275 ? 105.713 137.775 96.446  1.00 19.40  ? 270 ILE B CG1   1 
ATOM   5957 C CG2   . ILE C 3 275 ? 108.019 138.681 96.053  1.00 19.40  ? 270 ILE B CG2   1 
ATOM   5958 C CD1   . ILE C 3 275 ? 105.019 138.713 95.478  1.00 19.40  ? 270 ILE B CD1   1 
ATOM   5959 N N     . CYS C 3 276 ? 108.853 134.925 94.434  1.00 15.84  ? 271 CYS B N     1 
ATOM   5960 C CA    . CYS C 3 276 ? 110.188 134.372 94.277  1.00 15.84  ? 271 CYS B CA    1 
ATOM   5961 C C     . CYS C 3 276 ? 110.273 133.553 92.995  1.00 15.84  ? 271 CYS B C     1 
ATOM   5962 O O     . CYS C 3 276 ? 109.274 133.324 92.308  1.00 15.84  ? 271 CYS B O     1 
ATOM   5963 C CB    . CYS C 3 276 ? 110.566 133.510 95.484  1.00 15.84  ? 271 CYS B CB    1 
ATOM   5964 S SG    . CYS C 3 276 ? 109.357 132.232 95.876  1.00 15.84  ? 271 CYS B SG    1 
ATOM   5965 N N     . GLY C 3 277 ? 111.493 133.101 92.687  1.00 14.36  ? 272 GLY B N     1 
ATOM   5966 C CA    . GLY C 3 277 ? 111.768 132.469 91.414  1.00 14.36  ? 272 GLY B CA    1 
ATOM   5967 C C     . GLY C 3 277 ? 111.352 131.010 91.346  1.00 14.36  ? 272 GLY B C     1 
ATOM   5968 O O     . GLY C 3 277 ? 110.830 130.433 92.297  1.00 14.36  ? 272 GLY B O     1 
ATOM   5969 N N     . ILE C 3 278 ? 111.597 130.420 90.180  1.00 12.94  ? 273 ILE B N     1 
ATOM   5970 C CA    . ILE C 3 278 ? 111.276 129.022 89.916  1.00 12.94  ? 273 ILE B CA    1 
ATOM   5971 C C     . ILE C 3 278 ? 112.583 128.254 89.775  1.00 12.94  ? 273 ILE B C     1 
ATOM   5972 O O     . ILE C 3 278 ? 113.433 128.607 88.951  1.00 12.94  ? 273 ILE B O     1 
ATOM   5973 C CB    . ILE C 3 278 ? 110.416 128.881 88.652  1.00 12.94  ? 273 ILE B CB    1 
ATOM   5974 C CG1   . ILE C 3 278 ? 109.081 129.596 88.843  1.00 12.94  ? 273 ILE B CG1   1 
ATOM   5975 C CG2   . ILE C 3 278 ? 110.190 127.415 88.325  1.00 12.94  ? 273 ILE B CG2   1 
ATOM   5976 C CD1   . ILE C 3 278 ? 109.107 131.049 88.443  1.00 12.94  ? 273 ILE B CD1   1 
ATOM   5977 N N     . THR C 3 279 ? 112.746 127.205 90.578  1.00 9.56   ? 274 THR B N     1 
ATOM   5978 C CA    . THR C 3 279 ? 113.984 126.436 90.580  1.00 9.56   ? 274 THR B CA    1 
ATOM   5979 C C     . THR C 3 279 ? 113.988 125.301 89.566  1.00 9.56   ? 274 THR B C     1 
ATOM   5980 O O     . THR C 3 279 ? 115.057 124.939 89.062  1.00 9.56   ? 274 THR B O     1 
ATOM   5981 C CB    . THR C 3 279 ? 114.242 125.854 91.971  1.00 9.56   ? 274 THR B CB    1 
ATOM   5982 O OG1   . THR C 3 279 ? 113.021 125.329 92.507  1.00 9.56   ? 274 THR B OG1   1 
ATOM   5983 C CG2   . THR C 3 279 ? 114.786 126.914 92.905  1.00 9.56   ? 274 THR B CG2   1 
ATOM   5984 N N     . SER C 3 280 ? 112.827 124.729 89.259  1.00 9.09   ? 275 SER B N     1 
ATOM   5985 C CA    . SER C 3 280 ? 112.745 123.578 88.375  1.00 9.09   ? 275 SER B CA    1 
ATOM   5986 C C     . SER C 3 280 ? 111.408 123.588 87.654  1.00 9.09   ? 275 SER B C     1 
ATOM   5987 O O     . SER C 3 280 ? 110.414 124.101 88.169  1.00 9.09   ? 275 SER B O     1 
ATOM   5988 C CB    . SER C 3 280 ? 112.909 122.267 89.150  1.00 9.09   ? 275 SER B CB    1 
ATOM   5989 O OG    . SER C 3 280 ? 111.937 122.165 90.173  1.00 9.09   ? 275 SER B OG    1 
ATOM   5990 N N     . VAL C 3 281 ? 111.395 123.003 86.460  1.00 13.01  ? 276 VAL B N     1 
ATOM   5991 C CA    . VAL C 3 281 ? 110.199 122.930 85.633  1.00 13.01  ? 276 VAL B CA    1 
ATOM   5992 C C     . VAL C 3 281 ? 110.092 121.527 85.056  1.00 13.01  ? 276 VAL B C     1 
ATOM   5993 O O     . VAL C 3 281 ? 111.096 120.899 84.707  1.00 13.01  ? 276 VAL B O     1 
ATOM   5994 C CB    . VAL C 3 281 ? 110.214 123.986 84.505  1.00 13.01  ? 276 VAL B CB    1 
ATOM   5995 C CG1   . VAL C 3 281 ? 108.963 123.873 83.658  1.00 13.01  ? 276 VAL B CG1   1 
ATOM   5996 C CG2   . VAL C 3 281 ? 110.322 125.380 85.090  1.00 13.01  ? 276 VAL B CG2   1 
ATOM   5997 N N     . SER C 3 282 ? 108.860 121.032 84.965  1.00 12.05  ? 277 SER B N     1 
ATOM   5998 C CA    . SER C 3 282 ? 108.610 119.710 84.412  1.00 12.05  ? 277 SER B CA    1 
ATOM   5999 C C     . SER C 3 282 ? 107.195 119.677 83.861  1.00 12.05  ? 277 SER B C     1 
ATOM   6000 O O     . SER C 3 282 ? 106.340 120.476 84.248  1.00 12.05  ? 277 SER B O     1 
ATOM   6001 C CB    . SER C 3 282 ? 108.808 118.613 85.462  1.00 12.05  ? 277 SER B CB    1 
ATOM   6002 O OG    . SER C 3 282 ? 110.145 118.593 85.932  1.00 12.05  ? 277 SER B OG    1 
ATOM   6003 N N     . PHE C 3 283 ? 106.959 118.733 82.957  1.00 16.69  ? 278 PHE B N     1 
ATOM   6004 C CA    . PHE C 3 283 ? 105.682 118.597 82.278  1.00 16.69  ? 278 PHE B CA    1 
ATOM   6005 C C     . PHE C 3 283 ? 105.042 117.260 82.622  1.00 16.69  ? 278 PHE B C     1 
ATOM   6006 O O     . PHE C 3 283 ? 105.723 116.281 82.939  1.00 16.69  ? 278 PHE B O     1 
ATOM   6007 C CB    . PHE C 3 283 ? 105.846 118.701 80.758  1.00 16.69  ? 278 PHE B CB    1 
ATOM   6008 C CG    . PHE C 3 283 ? 105.837 120.108 80.238  1.00 16.69  ? 278 PHE B CG    1 
ATOM   6009 C CD1   . PHE C 3 283 ? 106.983 120.883 80.281  1.00 16.69  ? 278 PHE B CD1   1 
ATOM   6010 C CD2   . PHE C 3 283 ? 104.684 120.653 79.700  1.00 16.69  ? 278 PHE B CD2   1 
ATOM   6011 C CE1   . PHE C 3 283 ? 106.978 122.175 79.798  1.00 16.69  ? 278 PHE B CE1   1 
ATOM   6012 C CE2   . PHE C 3 283 ? 104.674 121.944 79.217  1.00 16.69  ? 278 PHE B CE2   1 
ATOM   6013 C CZ    . PHE C 3 283 ? 105.821 122.706 79.264  1.00 16.69  ? 278 PHE B CZ    1 
ATOM   6014 N N     . SER C 3 284 ? 103.716 117.232 82.554  1.00 19.17  ? 279 SER B N     1 
ATOM   6015 C CA    . SER C 3 284 ? 102.983 115.985 82.669  1.00 19.17  ? 279 SER B CA    1 
ATOM   6016 C C     . SER C 3 284 ? 103.205 115.136 81.422  1.00 19.17  ? 279 SER B C     1 
ATOM   6017 O O     . SER C 3 284 ? 103.606 115.631 80.365  1.00 19.17  ? 279 SER B O     1 
ATOM   6018 C CB    . SER C 3 284 ? 101.491 116.253 82.862  1.00 19.17  ? 279 SER B CB    1 
ATOM   6019 O OG    . SER C 3 284 ? 100.751 115.046 82.858  1.00 19.17  ? 279 SER B OG    1 
ATOM   6020 N N     . LYS C 3 285 ? 102.940 113.835 81.556  1.00 20.48  ? 280 LYS B N     1 
ATOM   6021 C CA    . LYS C 3 285 ? 103.093 112.939 80.415  1.00 20.48  ? 280 LYS B CA    1 
ATOM   6022 C C     . LYS C 3 285 ? 102.272 113.417 79.227  1.00 20.48  ? 280 LYS B C     1 
ATOM   6023 O O     . LYS C 3 285 ? 102.673 113.222 78.074  1.00 20.48  ? 280 LYS B O     1 
ATOM   6024 C CB    . LYS C 3 285 ? 102.683 111.518 80.804  1.00 20.48  ? 280 LYS B CB    1 
ATOM   6025 C CG    . LYS C 3 285 ? 103.281 110.439 79.917  1.00 20.48  ? 280 LYS B CG    1 
ATOM   6026 C CD    . LYS C 3 285 ? 102.284 109.328 79.635  1.00 20.48  ? 280 LYS B CD    1 
ATOM   6027 C CE    . LYS C 3 285 ? 102.868 108.286 78.695  1.00 20.48  ? 280 LYS B CE    1 
ATOM   6028 N NZ    . LYS C 3 285 ? 102.033 107.055 78.632  1.00 20.48  ? 280 LYS B NZ    1 
ATOM   6029 N N     . SER C 3 286 ? 101.128 114.044 79.484  1.00 27.99  ? 281 SER B N     1 
ATOM   6030 C CA    . SER C 3 286 ? 100.310 114.635 78.435  1.00 27.99  ? 281 SER B CA    1 
ATOM   6031 C C     . SER C 3 286 ? 100.718 116.060 78.096  1.00 27.99  ? 281 SER B C     1 
ATOM   6032 O O     . SER C 3 286 ? 100.182 116.629 77.140  1.00 27.99  ? 281 SER B O     1 
ATOM   6033 C CB    . SER C 3 286 ? 98.837  114.634 78.852  1.00 27.99  ? 281 SER B CB    1 
ATOM   6034 O OG    . SER C 3 286 ? 98.025  115.223 77.852  1.00 27.99  ? 281 SER B OG    1 
ATOM   6035 N N     . GLY C 3 287 ? 101.643 116.649 78.849  1.00 25.78  ? 282 GLY B N     1 
ATOM   6036 C CA    . GLY C 3 287 ? 101.927 118.061 78.695  1.00 25.78  ? 282 GLY B CA    1 
ATOM   6037 C C     . GLY C 3 287 ? 100.778 118.947 79.119  1.00 25.78  ? 282 GLY B C     1 
ATOM   6038 O O     . GLY C 3 287 ? 100.728 120.117 78.731  1.00 25.78  ? 282 GLY B O     1 
ATOM   6039 N N     . ARG C 3 288 ? 99.849  118.413 79.911  1.00 27.33  ? 283 ARG B N     1 
ATOM   6040 C CA    . ARG C 3 288 ? 98.677  119.156 80.350  1.00 27.33  ? 283 ARG B CA    1 
ATOM   6041 C C     . ARG C 3 288 ? 98.892  119.882 81.668  1.00 27.33  ? 283 ARG B C     1 
ATOM   6042 O O     . ARG C 3 288 ? 98.181  120.854 81.943  1.00 27.33  ? 283 ARG B O     1 
ATOM   6043 C CB    . ARG C 3 288 ? 97.479  118.206 80.482  1.00 27.33  ? 283 ARG B CB    1 
ATOM   6044 C CG    . ARG C 3 288 ? 96.225  118.823 81.082  1.00 27.33  ? 283 ARG B CG    1 
ATOM   6045 C CD    . ARG C 3 288 ? 95.694  119.970 80.240  1.00 27.33  ? 283 ARG B CD    1 
ATOM   6046 N NE    . ARG C 3 288 ? 94.399  120.430 80.725  1.00 27.33  ? 283 ARG B NE    1 
ATOM   6047 C CZ    . ARG C 3 288 ? 93.790  121.533 80.312  1.00 27.33  ? 283 ARG B CZ    1 
ATOM   6048 N NH1   . ARG C 3 288 ? 94.338  122.330 79.410  1.00 27.33  ? 283 ARG B NH1   1 
ATOM   6049 N NH2   . ARG C 3 288 ? 92.601  121.845 80.818  1.00 27.33  ? 283 ARG B NH2   1 
ATOM   6050 N N     . LEU C 3 289 ? 99.848  119.441 82.480  1.00 19.36  ? 284 LEU B N     1 
ATOM   6051 C CA    . LEU C 3 289 ? 100.164 120.088 83.746  1.00 19.36  ? 284 LEU B CA    1 
ATOM   6052 C C     . LEU C 3 289 ? 101.639 120.448 83.748  1.00 19.36  ? 284 LEU B C     1 
ATOM   6053 O O     . LEU C 3 289 ? 102.494 119.575 83.572  1.00 19.36  ? 284 LEU B O     1 
ATOM   6054 C CB    . LEU C 3 289 ? 99.838  119.180 84.935  1.00 19.36  ? 284 LEU B CB    1 
ATOM   6055 C CG    . LEU C 3 289 ? 98.440  118.561 84.965  1.00 19.36  ? 284 LEU B CG    1 
ATOM   6056 C CD1   . LEU C 3 289 ? 98.341  117.554 86.096  1.00 19.36  ? 284 LEU B CD1   1 
ATOM   6057 C CD2   . LEU C 3 289 ? 97.381  119.640 85.107  1.00 19.36  ? 284 LEU B CD2   1 
ATOM   6058 N N     . LEU C 3 290 ? 101.934 121.729 83.945  1.00 15.46  ? 285 LEU B N     1 
ATOM   6059 C CA    . LEU C 3 290 ? 103.306 122.209 84.078  1.00 15.46  ? 285 LEU B CA    1 
ATOM   6060 C C     . LEU C 3 290 ? 103.608 122.309 85.567  1.00 15.46  ? 285 LEU B C     1 
ATOM   6061 O O     . LEU C 3 290 ? 103.005 123.108 86.283  1.00 15.46  ? 285 LEU B O     1 
ATOM   6062 C CB    . LEU C 3 290 ? 103.473 123.548 83.370  1.00 15.46  ? 285 LEU B CB    1 
ATOM   6063 C CG    . LEU C 3 290 ? 104.794 124.287 83.588  1.00 15.46  ? 285 LEU B CG    1 
ATOM   6064 C CD1   . LEU C 3 290 ? 105.886 123.701 82.717  1.00 15.46  ? 285 LEU B CD1   1 
ATOM   6065 C CD2   . LEU C 3 290 ? 104.618 125.765 83.299  1.00 15.46  ? 285 LEU B CD2   1 
ATOM   6066 N N     . LEU C 3 291 ? 104.530 121.485 86.044  1.00 12.04  ? 286 LEU B N     1 
ATOM   6067 C CA    . LEU C 3 291 ? 104.901 121.491 87.449  1.00 12.04  ? 286 LEU B CA    1 
ATOM   6068 C C     . LEU C 3 291 ? 106.142 122.352 87.633  1.00 12.04  ? 286 LEU B C     1 
ATOM   6069 O O     . LEU C 3 291 ? 107.133 122.182 86.917  1.00 12.04  ? 286 LEU B O     1 
ATOM   6070 C CB    . LEU C 3 291 ? 105.149 120.067 87.945  1.00 12.04  ? 286 LEU B CB    1 
ATOM   6071 C CG    . LEU C 3 291 ? 103.881 119.219 88.088  1.00 12.04  ? 286 LEU B CG    1 
ATOM   6072 C CD1   . LEU C 3 291 ? 103.415 118.682 86.742  1.00 12.04  ? 286 LEU B CD1   1 
ATOM   6073 C CD2   . LEU C 3 291 ? 104.115 118.084 89.057  1.00 12.04  ? 286 LEU B CD2   1 
ATOM   6074 N N     . ALA C 3 292 ? 106.082 123.281 88.585  1.00 10.52  ? 287 ALA B N     1 
ATOM   6075 C CA    . ALA C 3 292 ? 107.154 124.241 88.800  1.00 10.52  ? 287 ALA B CA    1 
ATOM   6076 C C     . ALA C 3 292 ? 107.517 124.277 90.274  1.00 10.52  ? 287 ALA B C     1 
ATOM   6077 O O     . ALA C 3 292 ? 106.640 124.416 91.131  1.00 10.52  ? 287 ALA B O     1 
ATOM   6078 C CB    . ALA C 3 292 ? 106.744 125.637 88.321  1.00 10.52  ? 287 ALA B CB    1 
ATOM   6079 N N     . GLY C 3 293 ? 108.809 124.163 90.563  1.00 8.91   ? 288 GLY B N     1 
ATOM   6080 C CA    . GLY C 3 293 ? 109.298 124.289 91.922  1.00 8.91   ? 288 GLY B CA    1 
ATOM   6081 C C     . GLY C 3 293 ? 109.771 125.709 92.188  1.00 8.91   ? 288 GLY B C     1 
ATOM   6082 O O     . GLY C 3 293 ? 110.574 126.262 91.440  1.00 8.91   ? 288 GLY B O     1 
ATOM   6083 N N     . TYR C 3 294 ? 109.262 126.287 93.269  1.00 10.92  ? 289 TYR B N     1 
ATOM   6084 C CA    . TYR C 3 294 ? 109.526 127.672 93.624  1.00 10.92  ? 289 TYR B CA    1 
ATOM   6085 C C     . TYR C 3 294 ? 110.409 127.733 94.862  1.00 10.92  ? 289 TYR B C     1 
ATOM   6086 O O     . TYR C 3 294 ? 110.676 126.725 95.521  1.00 10.92  ? 289 TYR B O     1 
ATOM   6087 C CB    . TYR C 3 294 ? 108.217 128.430 93.872  1.00 10.92  ? 289 TYR B CB    1 
ATOM   6088 C CG    . TYR C 3 294 ? 107.359 128.578 92.641  1.00 10.92  ? 289 TYR B CG    1 
ATOM   6089 C CD1   . TYR C 3 294 ? 106.679 127.493 92.113  1.00 10.92  ? 289 TYR B CD1   1 
ATOM   6090 C CD2   . TYR C 3 294 ? 107.221 129.805 92.011  1.00 10.92  ? 289 TYR B CD2   1 
ATOM   6091 C CE1   . TYR C 3 294 ? 105.893 127.624 90.989  1.00 10.92  ? 289 TYR B CE1   1 
ATOM   6092 C CE2   . TYR C 3 294 ? 106.436 129.945 90.886  1.00 10.92  ? 289 TYR B CE2   1 
ATOM   6093 C CZ    . TYR C 3 294 ? 105.775 128.850 90.380  1.00 10.92  ? 289 TYR B CZ    1 
ATOM   6094 O OH    . TYR C 3 294 ? 104.991 128.982 89.260  1.00 10.92  ? 289 TYR B OH    1 
ATOM   6095 N N     . ASP C 3 295 ? 110.870 128.942 95.169  1.00 11.87  ? 290 ASP B N     1 
ATOM   6096 C CA    . ASP C 3 295 ? 111.628 129.196 96.383  1.00 11.87  ? 290 ASP B CA    1 
ATOM   6097 C C     . ASP C 3 295 ? 110.729 129.354 97.600  1.00 11.87  ? 290 ASP B C     1 
ATOM   6098 O O     . ASP C 3 295 ? 111.236 129.475 98.720  1.00 11.87  ? 290 ASP B O     1 
ATOM   6099 C CB    . ASP C 3 295 ? 112.489 130.449 96.215  1.00 11.87  ? 290 ASP B CB    1 
ATOM   6100 C CG    . ASP C 3 295 ? 113.249 130.464 94.904  1.00 11.87  ? 290 ASP B CG    1 
ATOM   6101 O OD1   . ASP C 3 295 ? 114.084 129.566 94.682  1.00 11.87  ? 290 ASP B OD1   1 
ATOM   6102 O OD2   . ASP C 3 295 ? 113.014 131.384 94.094  1.00 11.87  ? 290 ASP B OD2   1 
ATOM   6103 N N     . ASP C 3 296 ? 109.413 129.350 97.405  1.00 12.43  ? 291 ASP B N     1 
ATOM   6104 C CA    . ASP C 3 296 ? 108.442 129.493 98.479  1.00 12.43  ? 291 ASP B CA    1 
ATOM   6105 C C     . ASP C 3 296 ? 108.215 128.198 99.243  1.00 12.43  ? 291 ASP B C     1 
ATOM   6106 O O     . ASP C 3 296 ? 107.203 128.081 99.942  1.00 12.43  ? 291 ASP B O     1 
ATOM   6107 C CB    . ASP C 3 296 ? 107.112 129.996 97.914  1.00 12.43  ? 291 ASP B CB    1 
ATOM   6108 C CG    . ASP C 3 296 ? 106.279 130.730 98.945  1.00 12.43  ? 291 ASP B CG    1 
ATOM   6109 O OD1   . ASP C 3 296 ? 106.672 130.741 100.131 1.00 12.43  ? 291 ASP B OD1   1 
ATOM   6110 O OD2   . ASP C 3 296 ? 105.231 131.297 98.571  1.00 12.43  ? 291 ASP B OD2   1 
ATOM   6111 N N     . PHE C 3 297 ? 109.114 127.224 99.106  1.00 9.88   ? 292 PHE B N     1 
ATOM   6112 C CA    . PHE C 3 297 ? 109.060 125.931 99.780  1.00 9.88   ? 292 PHE B CA    1 
ATOM   6113 C C     . PHE C 3 297 ? 107.974 125.025 99.219  1.00 9.88   ? 292 PHE B C     1 
ATOM   6114 O O     . PHE C 3 297 ? 107.753 123.933 99.756  1.00 9.88   ? 292 PHE B O     1 
ATOM   6115 C CB    . PHE C 3 297 ? 108.852 126.082 101.294 1.00 9.88   ? 292 PHE B CB    1 
ATOM   6116 C CG    . PHE C 3 297 ? 110.010 126.721 102.017 1.00 9.88   ? 292 PHE B CG    1 
ATOM   6117 C CD1   . PHE C 3 297 ? 111.086 127.255 101.325 1.00 9.88   ? 292 PHE B CD1   1 
ATOM   6118 C CD2   . PHE C 3 297 ? 110.017 126.783 103.398 1.00 9.88   ? 292 PHE B CD2   1 
ATOM   6119 C CE1   . PHE C 3 297 ? 112.141 127.835 101.999 1.00 9.88   ? 292 PHE B CE1   1 
ATOM   6120 C CE2   . PHE C 3 297 ? 111.071 127.362 104.076 1.00 9.88   ? 292 PHE B CE2   1 
ATOM   6121 C CZ    . PHE C 3 297 ? 112.133 127.889 103.376 1.00 9.88   ? 292 PHE B CZ    1 
ATOM   6122 N N     . ASN C 3 298 ? 107.293 125.437 98.153  1.00 10.28  ? 293 ASN B N     1 
ATOM   6123 C CA    . ASN C 3 298 ? 106.195 124.673 97.584  1.00 10.28  ? 293 ASN B CA    1 
ATOM   6124 C C     . ASN C 3 298 ? 106.446 124.429 96.104  1.00 10.28  ? 293 ASN B C     1 
ATOM   6125 O O     . ASN C 3 298 ? 107.345 125.014 95.496  1.00 10.28  ? 293 ASN B O     1 
ATOM   6126 C CB    . ASN C 3 298 ? 104.852 125.395 97.765  1.00 10.28  ? 293 ASN B CB    1 
ATOM   6127 C CG    . ASN C 3 298 ? 104.550 125.710 99.215  1.00 10.28  ? 293 ASN B CG    1 
ATOM   6128 O OD1   . ASN C 3 298 ? 105.198 125.191 100.124 1.00 10.28  ? 293 ASN B OD1   1 
ATOM   6129 N ND2   . ASN C 3 298 ? 103.560 126.567 99.441  1.00 10.28  ? 293 ASN B ND2   1 
ATOM   6130 N N     . CYS C 3 299 ? 105.636 123.542 95.537  1.00 9.14   ? 294 CYS B N     1 
ATOM   6131 C CA    . CYS C 3 299 ? 105.624 123.263 94.109  1.00 9.14   ? 294 CYS B CA    1 
ATOM   6132 C C     . CYS C 3 299 ? 104.215 123.493 93.588  1.00 9.14   ? 294 CYS B C     1 
ATOM   6133 O O     . CYS C 3 299 ? 103.246 122.988 94.165  1.00 9.14   ? 294 CYS B O     1 
ATOM   6134 C CB    . CYS C 3 299 ? 106.077 121.829 93.822  1.00 9.14   ? 294 CYS B CB    1 
ATOM   6135 S SG    . CYS C 3 299 ? 105.834 121.300 92.112  1.00 9.14   ? 294 CYS B SG    1 
ATOM   6136 N N     . ASN C 3 300 ? 104.103 124.255 92.506  1.00 11.67  ? 295 ASN B N     1 
ATOM   6137 C CA    . ASN C 3 300 ? 102.817 124.631 91.941  1.00 11.67  ? 295 ASN B CA    1 
ATOM   6138 C C     . ASN C 3 300 ? 102.564 123.865 90.651  1.00 11.67  ? 295 ASN B C     1 
ATOM   6139 O O     . ASN C 3 300 ? 103.476 123.664 89.842  1.00 11.67  ? 295 ASN B O     1 
ATOM   6140 C CB    . ASN C 3 300 ? 102.750 126.136 91.666  1.00 11.67  ? 295 ASN B CB    1 
ATOM   6141 C CG    . ASN C 3 300 ? 102.914 126.966 92.923  1.00 11.67  ? 295 ASN B CG    1 
ATOM   6142 O OD1   . ASN C 3 300 ? 103.992 127.013 93.515  1.00 11.67  ? 295 ASN B OD1   1 
ATOM   6143 N ND2   . ASN C 3 300 ? 101.841 127.625 93.339  1.00 11.67  ? 295 ASN B ND2   1 
ATOM   6144 N N     . VAL C 3 301 ? 101.320 123.437 90.471  1.00 13.92  ? 296 VAL B N     1 
ATOM   6145 C CA    . VAL C 3 301 ? 100.872 122.794 89.244  1.00 13.92  ? 296 VAL B CA    1 
ATOM   6146 C C     . VAL C 3 301 ? 100.061 123.811 88.457  1.00 13.92  ? 296 VAL B C     1 
ATOM   6147 O O     . VAL C 3 301 ? 99.081  124.366 88.969  1.00 13.92  ? 296 VAL B O     1 
ATOM   6148 C CB    . VAL C 3 301 ? 100.041 121.535 89.545  1.00 13.92  ? 296 VAL B CB    1 
ATOM   6149 C CG1   . VAL C 3 301 ? 99.632  120.845 88.257  1.00 13.92  ? 296 VAL B CG1   1 
ATOM   6150 C CG2   . VAL C 3 301 ? 100.825 120.585 90.436  1.00 13.92  ? 296 VAL B CG2   1 
ATOM   6151 N N     . TRP C 3 302 ? 100.467 124.059 87.216  1.00 14.03  ? 297 TRP B N     1 
ATOM   6152 C CA    . TRP C 3 302 ? 99.854  125.063 86.364  1.00 14.03  ? 297 TRP B CA    1 
ATOM   6153 C C     . TRP C 3 302 ? 99.158  124.382 85.198  1.00 14.03  ? 297 TRP B C     1 
ATOM   6154 O O     . TRP C 3 302 ? 99.731  123.500 84.553  1.00 14.03  ? 297 TRP B O     1 
ATOM   6155 C CB    . TRP C 3 302 ? 100.903 126.044 85.827  1.00 14.03  ? 297 TRP B CB    1 
ATOM   6156 C CG    . TRP C 3 302 ? 101.614 126.819 86.888  1.00 14.03  ? 297 TRP B CG    1 
ATOM   6157 C CD1   . TRP C 3 302 ? 102.720 126.432 87.584  1.00 14.03  ? 297 TRP B CD1   1 
ATOM   6158 C CD2   . TRP C 3 302 ? 101.272 128.122 87.371  1.00 14.03  ? 297 TRP B CD2   1 
ATOM   6159 N NE1   . TRP C 3 302 ? 103.085 127.411 88.475  1.00 14.03  ? 297 TRP B NE1   1 
ATOM   6160 C CE2   . TRP C 3 302 ? 102.211 128.459 88.362  1.00 14.03  ? 297 TRP B CE2   1 
ATOM   6161 C CE3   . TRP C 3 302 ? 100.261 129.034 87.062  1.00 14.03  ? 297 TRP B CE3   1 
ATOM   6162 C CZ2   . TRP C 3 302 ? 102.169 129.669 89.045  1.00 14.03  ? 297 TRP B CZ2   1 
ATOM   6163 C CZ3   . TRP C 3 302 ? 100.221 130.232 87.740  1.00 14.03  ? 297 TRP B CZ3   1 
ATOM   6164 C CH2   . TRP C 3 302 ? 101.168 130.540 88.721  1.00 14.03  ? 297 TRP B CH2   1 
ATOM   6165 N N     . ASP C 3 303 ? 97.921  124.782 84.933  1.00 25.28  ? 298 ASP B N     1 
ATOM   6166 C CA    . ASP C 3 303 ? 97.282  124.380 83.692  1.00 25.28  ? 298 ASP B CA    1 
ATOM   6167 C C     . ASP C 3 303 ? 98.046  124.975 82.517  1.00 25.28  ? 298 ASP B C     1 
ATOM   6168 O O     . ASP C 3 303 ? 98.005  126.185 82.276  1.00 25.28  ? 298 ASP B O     1 
ATOM   6169 C CB    . ASP C 3 303 ? 95.826  124.839 83.668  1.00 25.28  ? 298 ASP B CB    1 
ATOM   6170 C CG    . ASP C 3 303 ? 94.954  123.957 82.803  1.00 25.28  ? 298 ASP B CG    1 
ATOM   6171 O OD1   . ASP C 3 303 ? 95.304  123.750 81.623  1.00 25.28  ? 298 ASP B OD1   1 
ATOM   6172 O OD2   . ASP C 3 303 ? 93.915  123.475 83.300  1.00 25.28  ? 298 ASP B OD2   1 
ATOM   6173 N N     . ALA C 3 304 ? 98.749  124.114 81.780  1.00 24.55  ? 299 ALA B N     1 
ATOM   6174 C CA    . ALA C 3 304 ? 99.637  124.581 80.724  1.00 24.55  ? 299 ALA B CA    1 
ATOM   6175 C C     . ALA C 3 304 ? 98.905  125.362 79.643  1.00 24.55  ? 299 ALA B C     1 
ATOM   6176 O O     . ALA C 3 304 ? 99.541  126.145 78.929  1.00 24.55  ? 299 ALA B O     1 
ATOM   6177 C CB    . ALA C 3 304 ? 100.371 123.397 80.093  1.00 24.55  ? 299 ALA B CB    1 
ATOM   6178 N N     . LEU C 3 305 ? 97.592  125.173 79.506  1.00 35.16  ? 300 LEU B N     1 
ATOM   6179 C CA    . LEU C 3 305 ? 96.802  125.906 78.530  1.00 35.16  ? 300 LEU B CA    1 
ATOM   6180 C C     . LEU C 3 305 ? 96.004  127.056 79.125  1.00 35.16  ? 300 LEU B C     1 
ATOM   6181 O O     . LEU C 3 305 ? 95.703  128.010 78.399  1.00 35.16  ? 300 LEU B O     1 
ATOM   6182 C CB    . LEU C 3 305 ? 95.826  124.961 77.810  1.00 35.16  ? 300 LEU B CB    1 
ATOM   6183 C CG    . LEU C 3 305 ? 96.441  123.755 77.096  1.00 35.16  ? 300 LEU B CG    1 
ATOM   6184 C CD1   . LEU C 3 305 ? 95.351  122.912 76.449  1.00 35.16  ? 300 LEU B CD1   1 
ATOM   6185 C CD2   . LEU C 3 305 ? 97.469  124.192 76.063  1.00 35.16  ? 300 LEU B CD2   1 
ATOM   6186 N N     . LYS C 3 306 ? 95.663  127.003 80.415  1.00 33.65  ? 301 LYS B N     1 
ATOM   6187 C CA    . LYS C 3 306 ? 94.892  128.056 81.060  1.00 33.65  ? 301 LYS B CA    1 
ATOM   6188 C C     . LYS C 3 306 ? 95.729  128.968 81.943  1.00 33.65  ? 301 LYS B C     1 
ATOM   6189 O O     . LYS C 3 306 ? 95.236  130.025 82.348  1.00 33.65  ? 301 LYS B O     1 
ATOM   6190 C CB    . LYS C 3 306 ? 93.768  127.451 81.913  1.00 33.65  ? 301 LYS B CB    1 
ATOM   6191 C CG    . LYS C 3 306 ? 93.029  126.300 81.253  1.00 33.65  ? 301 LYS B CG    1 
ATOM   6192 C CD    . LYS C 3 306 ? 92.270  126.757 80.024  1.00 33.65  ? 301 LYS B CD    1 
ATOM   6193 C CE    . LYS C 3 306 ? 91.143  125.797 79.686  1.00 33.65  ? 301 LYS B CE    1 
ATOM   6194 N NZ    . LYS C 3 306 ? 90.036  125.864 80.679  1.00 33.65  ? 301 LYS B NZ    1 
ATOM   6195 N N     . ALA C 3 307 ? 96.964  128.584 82.260  1.00 26.51  ? 302 ALA B N     1 
ATOM   6196 C CA    . ALA C 3 307 ? 97.882  129.387 83.064  1.00 26.51  ? 302 ALA B CA    1 
ATOM   6197 C C     . ALA C 3 307 ? 97.454  129.484 84.524  1.00 26.51  ? 302 ALA B C     1 
ATOM   6198 O O     . ALA C 3 307 ? 98.131  130.133 85.327  1.00 26.51  ? 302 ALA B O     1 
ATOM   6199 C CB    . ALA C 3 307 ? 98.047  130.794 82.479  1.00 26.51  ? 302 ALA B CB    1 
ATOM   6200 N N     . ASP C 3 308 ? 96.344  128.853 84.893  1.00 22.76  ? 303 ASP B N     1 
ATOM   6201 C CA    . ASP C 3 308 ? 95.897  128.870 86.274  1.00 22.76  ? 303 ASP B CA    1 
ATOM   6202 C C     . ASP C 3 308 ? 96.667  127.837 87.091  1.00 22.76  ? 303 ASP B C     1 
ATOM   6203 O O     . ASP C 3 308 ? 97.235  126.881 86.560  1.00 22.76  ? 303 ASP B O     1 
ATOM   6204 C CB    . ASP C 3 308 ? 94.396  128.598 86.350  1.00 22.76  ? 303 ASP B CB    1 
ATOM   6205 C CG    . ASP C 3 308 ? 93.583  129.596 85.552  1.00 22.76  ? 303 ASP B CG    1 
ATOM   6206 O OD1   . ASP C 3 308 ? 94.136  130.652 85.177  1.00 22.76  ? 303 ASP B OD1   1 
ATOM   6207 O OD2   . ASP C 3 308 ? 92.390  129.327 85.298  1.00 22.76  ? 303 ASP B OD2   1 
ATOM   6208 N N     . ARG C 3 309 ? 96.682  128.038 88.405  1.00 17.71  ? 304 ARG B N     1 
ATOM   6209 C CA    . ARG C 3 309 ? 97.300  127.101 89.335  1.00 17.71  ? 304 ARG B CA    1 
ATOM   6210 C C     . ARG C 3 309 ? 96.308  125.973 89.589  1.00 17.71  ? 304 ARG B C     1 
ATOM   6211 O O     . ARG C 3 309 ? 95.278  126.176 90.239  1.00 17.71  ? 304 ARG B O     1 
ATOM   6212 C CB    . ARG C 3 309 ? 97.693  127.794 90.638  1.00 17.71  ? 304 ARG B CB    1 
ATOM   6213 C CG    . ARG C 3 309 ? 98.755  128.865 90.473  1.00 17.71  ? 304 ARG B CG    1 
ATOM   6214 C CD    . ARG C 3 309 ? 99.237  129.386 91.816  1.00 17.71  ? 304 ARG B CD    1 
ATOM   6215 N NE    . ARG C 3 309 ? 98.264  130.281 92.435  1.00 17.71  ? 304 ARG B NE    1 
ATOM   6216 C CZ    . ARG C 3 309 ? 97.558  130.006 93.525  1.00 17.71  ? 304 ARG B CZ    1 
ATOM   6217 N NH1   . ARG C 3 309 ? 97.674  128.850 94.159  1.00 17.71  ? 304 ARG B NH1   1 
ATOM   6218 N NH2   . ARG C 3 309 ? 96.708  130.917 93.991  1.00 17.71  ? 304 ARG B NH2   1 
ATOM   6219 N N     . ALA C 3 310 ? 96.616  124.789 89.067  1.00 17.57  ? 305 ALA B N     1 
ATOM   6220 C CA    . ALA C 3 310 ? 95.748  123.628 89.199  1.00 17.57  ? 305 ALA B CA    1 
ATOM   6221 C C     . ALA C 3 310 ? 95.970  122.868 90.498  1.00 17.57  ? 305 ALA B C     1 
ATOM   6222 O O     . ALA C 3 310 ? 95.239  121.911 90.770  1.00 17.57  ? 305 ALA B O     1 
ATOM   6223 C CB    . ALA C 3 310 ? 95.954  122.683 88.012  1.00 17.57  ? 305 ALA B CB    1 
ATOM   6224 N N     . GLY C 3 311 ? 96.950  123.264 91.300  1.00 14.04  ? 306 GLY B N     1 
ATOM   6225 C CA    . GLY C 3 311 ? 97.192  122.596 92.559  1.00 14.04  ? 306 GLY B CA    1 
ATOM   6226 C C     . GLY C 3 311 ? 98.497  123.066 93.167  1.00 14.04  ? 306 GLY B C     1 
ATOM   6227 O O     . GLY C 3 311 ? 99.155  123.969 92.650  1.00 14.04  ? 306 GLY B O     1 
ATOM   6228 N N     . VAL C 3 312 ? 98.852  122.431 94.280  1.00 10.56  ? 307 VAL B N     1 
ATOM   6229 C CA    . VAL C 3 312 ? 100.095 122.740 94.976  1.00 10.56  ? 307 VAL B CA    1 
ATOM   6230 C C     . VAL C 3 312 ? 100.578 121.493 95.702  1.00 10.56  ? 307 VAL B C     1 
ATOM   6231 O O     . VAL C 3 312 ? 99.817  120.854 96.437  1.00 10.56  ? 307 VAL B O     1 
ATOM   6232 C CB    . VAL C 3 312 ? 99.912  123.915 95.953  1.00 10.56  ? 307 VAL B CB    1 
ATOM   6233 C CG1   . VAL C 3 312 ? 98.950  123.540 97.070  1.00 10.56  ? 307 VAL B CG1   1 
ATOM   6234 C CG2   . VAL C 3 312 ? 101.253 124.346 96.525  1.00 10.56  ? 307 VAL B CG2   1 
ATOM   6235 N N     . LEU C 3 313 ? 101.842 121.137 95.496  1.00 9.01   ? 308 LEU B N     1 
ATOM   6236 C CA    . LEU C 3 313 ? 102.449 120.006 96.191  1.00 9.01   ? 308 LEU B CA    1 
ATOM   6237 C C     . LEU C 3 313 ? 103.113 120.504 97.473  1.00 9.01   ? 308 LEU B C     1 
ATOM   6238 O O     . LEU C 3 313 ? 104.333 120.488 97.638  1.00 9.01   ? 308 LEU B O     1 
ATOM   6239 C CB    . LEU C 3 313 ? 103.440 119.292 95.277  1.00 9.01   ? 308 LEU B CB    1 
ATOM   6240 C CG    . LEU C 3 313 ? 102.843 118.370 94.213  1.00 9.01   ? 308 LEU B CG    1 
ATOM   6241 C CD1   . LEU C 3 313 ? 102.162 119.173 93.117  1.00 9.01   ? 308 LEU B CD1   1 
ATOM   6242 C CD2   . LEU C 3 313 ? 103.924 117.487 93.622  1.00 9.01   ? 308 LEU B CD2   1 
ATOM   6243 N N     . ALA C 3 314 ? 102.266 120.967 98.386  1.00 9.05   ? 309 ALA B N     1 
ATOM   6244 C CA    . ALA C 3 314 ? 102.736 121.406 99.691  1.00 9.05   ? 309 ALA B CA    1 
ATOM   6245 C C     . ALA C 3 314 ? 103.137 120.206 100.537 1.00 9.05   ? 309 ALA B C     1 
ATOM   6246 O O     . ALA C 3 314 ? 102.542 119.130 100.440 1.00 9.05   ? 309 ALA B O     1 
ATOM   6247 C CB    . ALA C 3 314 ? 101.653 122.214 100.401 1.00 9.05   ? 309 ALA B CB    1 
ATOM   6248 N N     . GLY C 3 315 ? 104.145 120.400 101.382 1.00 7.21   ? 310 GLY B N     1 
ATOM   6249 C CA    . GLY C 3 315 ? 104.675 119.315 102.183 1.00 7.21   ? 310 GLY B CA    1 
ATOM   6250 C C     . GLY C 3 315 ? 106.187 119.308 102.253 1.00 7.21   ? 310 GLY B C     1 
ATOM   6251 O O     . GLY C 3 315 ? 106.782 118.400 102.840 1.00 7.21   ? 310 GLY B O     1 
ATOM   6252 N N     . HIS C 3 316 ? 106.821 120.313 101.660 1.00 7.08   ? 311 HIS B N     1 
ATOM   6253 C CA    . HIS C 3 316 ? 108.263 120.484 101.727 1.00 7.08   ? 311 HIS B CA    1 
ATOM   6254 C C     . HIS C 3 316 ? 108.581 121.654 102.647 1.00 7.08   ? 311 HIS B C     1 
ATOM   6255 O O     . HIS C 3 316 ? 107.953 122.713 102.560 1.00 7.08   ? 311 HIS B O     1 
ATOM   6256 C CB    . HIS C 3 316 ? 108.856 120.718 100.335 1.00 7.08   ? 311 HIS B CB    1 
ATOM   6257 C CG    . HIS C 3 316 ? 109.155 119.455 99.588  1.00 7.08   ? 311 HIS B CG    1 
ATOM   6258 N ND1   . HIS C 3 316 ? 110.140 118.574 99.980  1.00 7.08   ? 311 HIS B ND1   1 
ATOM   6259 C CD2   . HIS C 3 316 ? 108.607 118.929 98.467  1.00 7.08   ? 311 HIS B CD2   1 
ATOM   6260 C CE1   . HIS C 3 316 ? 110.180 117.558 99.138  1.00 7.08   ? 311 HIS B CE1   1 
ATOM   6261 N NE2   . HIS C 3 316 ? 109.260 117.749 98.210  1.00 7.08   ? 311 HIS B NE2   1 
ATOM   6262 N N     . ASP C 3 317 ? 109.557 121.455 103.531 1.00 11.96  ? 312 ASP B N     1 
ATOM   6263 C CA    . ASP C 3 317 ? 109.911 122.436 104.546 1.00 11.96  ? 312 ASP B CA    1 
ATOM   6264 C C     . ASP C 3 317 ? 111.051 123.347 104.111 1.00 11.96  ? 312 ASP B C     1 
ATOM   6265 O O     . ASP C 3 317 ? 111.583 124.095 104.937 1.00 11.96  ? 312 ASP B O     1 
ATOM   6266 C CB    . ASP C 3 317 ? 110.281 121.728 105.852 1.00 11.96  ? 312 ASP B CB    1 
ATOM   6267 C CG    . ASP C 3 317 ? 109.070 121.167 106.573 1.00 11.96  ? 312 ASP B CG    1 
ATOM   6268 O OD1   . ASP C 3 317 ? 108.286 121.964 107.131 1.00 11.96  ? 312 ASP B OD1   1 
ATOM   6269 O OD2   . ASP C 3 317 ? 108.903 119.930 106.584 1.00 11.96  ? 312 ASP B OD2   1 
ATOM   6270 N N     . ASN C 3 318 ? 111.440 123.299 102.841 1.00 9.53   ? 313 ASN B N     1 
ATOM   6271 C CA    . ASN C 3 318 ? 112.472 124.180 102.315 1.00 9.53   ? 313 ASN B CA    1 
ATOM   6272 C C     . ASN C 3 318 ? 112.280 124.283 100.806 1.00 9.53   ? 313 ASN B C     1 
ATOM   6273 O O     . ASN C 3 318 ? 111.343 123.711 100.242 1.00 9.53   ? 313 ASN B O     1 
ATOM   6274 C CB    . ASN C 3 318 ? 113.864 123.671 102.707 1.00 9.53   ? 313 ASN B CB    1 
ATOM   6275 C CG    . ASN C 3 318 ? 114.897 124.778 102.756 1.00 9.53   ? 313 ASN B CG    1 
ATOM   6276 O OD1   . ASN C 3 318 ? 114.682 125.864 102.225 1.00 9.53   ? 313 ASN B OD1   1 
ATOM   6277 N ND2   . ASN C 3 318 ? 116.023 124.508 103.402 1.00 9.53   ? 313 ASN B ND2   1 
ATOM   6278 N N     . ARG C 3 319 ? 113.175 125.017 100.150 1.00 10.68  ? 314 ARG B N     1 
ATOM   6279 C CA    . ARG C 3 319 ? 113.043 125.275 98.721  1.00 10.68  ? 314 ARG B CA    1 
ATOM   6280 C C     . ARG C 3 319 ? 112.986 123.980 97.922  1.00 10.68  ? 314 ARG B C     1 
ATOM   6281 O O     . ARG C 3 319 ? 113.788 123.066 98.132  1.00 10.68  ? 314 ARG B O     1 
ATOM   6282 C CB    . ARG C 3 319 ? 114.211 126.139 98.246  1.00 10.68  ? 314 ARG B CB    1 
ATOM   6283 C CG    . ARG C 3 319 ? 114.228 126.387 96.751  1.00 10.68  ? 314 ARG B CG    1 
ATOM   6284 C CD    . ARG C 3 319 ? 115.283 127.405 96.356  1.00 10.68  ? 314 ARG B CD    1 
ATOM   6285 N NE    . ARG C 3 319 ? 115.104 128.690 97.020  1.00 10.68  ? 314 ARG B NE    1 
ATOM   6286 C CZ    . ARG C 3 319 ? 115.870 129.752 96.810  1.00 10.68  ? 314 ARG B CZ    1 
ATOM   6287 N NH1   . ARG C 3 319 ? 116.907 129.706 95.990  1.00 10.68  ? 314 ARG B NH1   1 
ATOM   6288 N NH2   . ARG C 3 319 ? 115.581 130.892 97.429  1.00 10.68  ? 314 ARG B NH2   1 
ATOM   6289 N N     . VAL C 3 320 ? 112.035 123.914 96.990  1.00 8.25   ? 315 VAL B N     1 
ATOM   6290 C CA    . VAL C 3 320 ? 111.882 122.768 96.095  1.00 8.25   ? 315 VAL B CA    1 
ATOM   6291 C C     . VAL C 3 320 ? 112.865 122.962 94.945  1.00 8.25   ? 315 VAL B C     1 
ATOM   6292 O O     . VAL C 3 320 ? 112.640 123.778 94.051  1.00 8.25   ? 315 VAL B O     1 
ATOM   6293 C CB    . VAL C 3 320 ? 110.444 122.624 95.592  1.00 8.25   ? 315 VAL B CB    1 
ATOM   6294 C CG1   . VAL C 3 320 ? 110.385 121.667 94.412  1.00 8.25   ? 315 VAL B CG1   1 
ATOM   6295 C CG2   . VAL C 3 320 ? 109.540 122.145 96.709  1.00 8.25   ? 315 VAL B CG2   1 
ATOM   6296 N N     . SER C 3 321 ? 113.958 122.199 94.958  1.00 7.74   ? 316 SER B N     1 
ATOM   6297 C CA    . SER C 3 321 ? 115.043 122.397 94.010  1.00 7.74   ? 316 SER B CA    1 
ATOM   6298 C C     . SER C 3 321 ? 114.841 121.681 92.683  1.00 7.74   ? 316 SER B C     1 
ATOM   6299 O O     . SER C 3 321 ? 115.236 122.224 91.646  1.00 7.74   ? 316 SER B O     1 
ATOM   6300 C CB    . SER C 3 321 ? 116.368 121.931 94.622  1.00 7.74   ? 316 SER B CB    1 
ATOM   6301 O OG    . SER C 3 321 ? 116.229 120.669 95.245  1.00 7.74   ? 316 SER B OG    1 
ATOM   6302 N N     . CYS C 3 322 ? 114.244 120.491 92.676  1.00 6.87   ? 317 CYS B N     1 
ATOM   6303 C CA    . CYS C 3 322 ? 114.150 119.707 91.453  1.00 6.87   ? 317 CYS B CA    1 
ATOM   6304 C C     . CYS C 3 322 ? 112.785 119.049 91.337  1.00 6.87   ? 317 CYS B C     1 
ATOM   6305 O O     . CYS C 3 322 ? 112.168 118.685 92.341  1.00 6.87   ? 317 CYS B O     1 
ATOM   6306 C CB    . CYS C 3 322 ? 115.243 118.633 91.394  1.00 6.87   ? 317 CYS B CB    1 
ATOM   6307 S SG    . CYS C 3 322 ? 115.456 117.705 92.920  1.00 6.87   ? 317 CYS B SG    1 
ATOM   6308 N N     . LEU C 3 323 ? 112.338 118.889 90.095  1.00 8.71   ? 318 LEU B N     1 
ATOM   6309 C CA    . LEU C 3 323 ? 111.113 118.187 89.759  1.00 8.71   ? 318 LEU B CA    1 
ATOM   6310 C C     . LEU C 3 323 ? 111.444 117.050 88.804  1.00 8.71   ? 318 LEU B C     1 
ATOM   6311 O O     . LEU C 3 323 ? 112.529 116.993 88.220  1.00 8.71   ? 318 LEU B O     1 
ATOM   6312 C CB    . LEU C 3 323 ? 110.086 119.125 89.110  1.00 8.71   ? 318 LEU B CB    1 
ATOM   6313 C CG    . LEU C 3 323 ? 109.115 119.830 90.051  1.00 8.71   ? 318 LEU B CG    1 
ATOM   6314 C CD1   . LEU C 3 323 ? 108.479 120.999 89.340  1.00 8.71   ? 318 LEU B CD1   1 
ATOM   6315 C CD2   . LEU C 3 323 ? 108.059 118.865 90.544  1.00 8.71   ? 318 LEU B CD2   1 
ATOM   6316 N N     . GLY C 3 324 ? 110.494 116.135 88.653  1.00 8.27   ? 319 GLY B N     1 
ATOM   6317 C CA    . GLY C 3 324 ? 110.629 115.085 87.665  1.00 8.27   ? 319 GLY B CA    1 
ATOM   6318 C C     . GLY C 3 324 ? 109.357 114.285 87.510  1.00 8.27   ? 319 GLY B C     1 
ATOM   6319 O O     . GLY C 3 324 ? 108.653 114.041 88.490  1.00 8.27   ? 319 GLY B O     1 
ATOM   6320 N N     . VAL C 3 325 ? 109.047 113.874 86.286  1.00 10.87  ? 320 VAL B N     1 
ATOM   6321 C CA    . VAL C 3 325 ? 107.872 113.062 86.001  1.00 10.87  ? 320 VAL B CA    1 
ATOM   6322 C C     . VAL C 3 325 ? 108.326 111.797 85.292  1.00 10.87  ? 320 VAL B C     1 
ATOM   6323 O O     . VAL C 3 325 ? 109.189 111.845 84.408  1.00 10.87  ? 320 VAL B O     1 
ATOM   6324 C CB    . VAL C 3 325 ? 106.841 113.827 85.147  1.00 10.87  ? 320 VAL B CB    1 
ATOM   6325 C CG1   . VAL C 3 325 ? 105.565 113.014 85.007  1.00 10.87  ? 320 VAL B CG1   1 
ATOM   6326 C CG2   . VAL C 3 325 ? 106.551 115.186 85.761  1.00 10.87  ? 320 VAL B CG2   1 
ATOM   6327 N N     . THR C 3 326 ? 107.750 110.665 85.684  1.00 10.95  ? 321 THR B N     1 
ATOM   6328 C CA    . THR C 3 326 ? 108.103 109.395 85.075  1.00 10.95  ? 321 THR B CA    1 
ATOM   6329 C C     . THR C 3 326 ? 107.783 109.417 83.583  1.00 10.95  ? 321 THR B C     1 
ATOM   6330 O O     . THR C 3 326 ? 107.074 110.292 83.079  1.00 10.95  ? 321 THR B O     1 
ATOM   6331 C CB    . THR C 3 326 ? 107.356 108.246 85.752  1.00 10.95  ? 321 THR B CB    1 
ATOM   6332 O OG1   . THR C 3 326 ? 105.944 108.470 85.661  1.00 10.95  ? 321 THR B OG1   1 
ATOM   6333 C CG2   . THR C 3 326 ? 107.753 108.122 87.210  1.00 10.95  ? 321 THR B CG2   1 
ATOM   6334 N N     . ASP C 3 327 ? 108.325 108.431 82.869  1.00 12.81  ? 322 ASP B N     1 
ATOM   6335 C CA    . ASP C 3 327 ? 108.065 108.323 81.440  1.00 12.81  ? 322 ASP B CA    1 
ATOM   6336 C C     . ASP C 3 327 ? 106.654 107.823 81.159  1.00 12.81  ? 322 ASP B C     1 
ATOM   6337 O O     . ASP C 3 327 ? 106.104 108.107 80.090  1.00 12.81  ? 322 ASP B O     1 
ATOM   6338 C CB    . ASP C 3 327 ? 109.096 107.400 80.792  1.00 12.81  ? 322 ASP B CB    1 
ATOM   6339 C CG    . ASP C 3 327 ? 110.518 107.888 80.995  1.00 12.81  ? 322 ASP B CG    1 
ATOM   6340 O OD1   . ASP C 3 327 ? 110.981 107.910 82.155  1.00 12.81  ? 322 ASP B OD1   1 
ATOM   6341 O OD2   . ASP C 3 327 ? 111.172 108.252 79.995  1.00 12.81  ? 322 ASP B OD2   1 
ATOM   6342 N N     . ASP C 3 328 ? 106.058 107.086 82.095  1.00 14.64  ? 323 ASP B N     1 
ATOM   6343 C CA    . ASP C 3 328 ? 104.672 106.658 81.974  1.00 14.64  ? 323 ASP B CA    1 
ATOM   6344 C C     . ASP C 3 328 ? 103.697 107.611 82.650  1.00 14.64  ? 323 ASP B C     1 
ATOM   6345 O O     . ASP C 3 328 ? 102.483 107.410 82.538  1.00 14.64  ? 323 ASP B O     1 
ATOM   6346 C CB    . ASP C 3 328 ? 104.495 105.254 82.563  1.00 14.64  ? 323 ASP B CB    1 
ATOM   6347 C CG    . ASP C 3 328 ? 104.979 105.158 83.995  1.00 14.64  ? 323 ASP B CG    1 
ATOM   6348 O OD1   . ASP C 3 328 ? 105.458 106.180 84.529  1.00 14.64  ? 323 ASP B OD1   1 
ATOM   6349 O OD2   . ASP C 3 328 ? 104.882 104.062 84.585  1.00 14.64  ? 323 ASP B OD2   1 
ATOM   6350 N N     . GLY C 3 329 ? 104.191 108.633 83.346  1.00 16.07  ? 324 GLY B N     1 
ATOM   6351 C CA    . GLY C 3 329 ? 103.315 109.607 83.966  1.00 16.07  ? 324 GLY B CA    1 
ATOM   6352 C C     . GLY C 3 329 ? 102.600 109.120 85.203  1.00 16.07  ? 324 GLY B C     1 
ATOM   6353 O O     . GLY C 3 329 ? 101.584 109.701 85.586  1.00 16.07  ? 324 GLY B O     1 
ATOM   6354 N N     . MET C 3 330 ? 103.099 108.063 85.841  1.00 14.96  ? 325 MET B N     1 
ATOM   6355 C CA    . MET C 3 330 ? 102.436 107.509 87.013  1.00 14.96  ? 325 MET B CA    1 
ATOM   6356 C C     . MET C 3 330 ? 102.657 108.335 88.273  1.00 14.96  ? 325 MET B C     1 
ATOM   6357 O O     . MET C 3 330 ? 101.765 108.378 89.126  1.00 14.96  ? 325 MET B O     1 
ATOM   6358 C CB    . MET C 3 330 ? 102.915 106.076 87.253  1.00 14.96  ? 325 MET B CB    1 
ATOM   6359 C CG    . MET C 3 330 ? 101.931 105.224 88.038  1.00 14.96  ? 325 MET B CG    1 
ATOM   6360 S SD    . MET C 3 330 ? 100.500 104.689 87.078  1.00 14.96  ? 325 MET B SD    1 
ATOM   6361 C CE    . MET C 3 330 ? 101.279 103.741 85.774  1.00 14.96  ? 325 MET B CE    1 
ATOM   6362 N N     . ALA C 3 331 ? 103.807 108.991 88.415  1.00 10.19  ? 326 ALA B N     1 
ATOM   6363 C CA    . ALA C 3 331 ? 104.124 109.693 89.650  1.00 10.19  ? 326 ALA B CA    1 
ATOM   6364 C C     . ALA C 3 331 ? 105.061 110.855 89.357  1.00 10.19  ? 326 ALA B C     1 
ATOM   6365 O O     . ALA C 3 331 ? 105.683 110.930 88.295  1.00 10.19  ? 326 ALA B O     1 
ATOM   6366 C CB    . ALA C 3 331 ? 104.748 108.746 90.677  1.00 10.19  ? 326 ALA B CB    1 
ATOM   6367 N N     . VAL C 3 332 ? 105.152 111.771 90.321  1.00 8.98   ? 327 VAL B N     1 
ATOM   6368 C CA    . VAL C 3 332 ? 106.034 112.930 90.241  1.00 8.98   ? 327 VAL B CA    1 
ATOM   6369 C C     . VAL C 3 332 ? 106.990 112.891 91.421  1.00 8.98   ? 327 VAL B C     1 
ATOM   6370 O O     . VAL C 3 332 ? 106.556 112.785 92.571  1.00 8.98   ? 327 VAL B O     1 
ATOM   6371 C CB    . VAL C 3 332 ? 105.253 114.258 90.248  1.00 8.98   ? 327 VAL B CB    1 
ATOM   6372 C CG1   . VAL C 3 332 ? 106.208 115.435 90.401  1.00 8.98   ? 327 VAL B CG1   1 
ATOM   6373 C CG2   . VAL C 3 332 ? 104.431 114.400 88.988  1.00 8.98   ? 327 VAL B CG2   1 
ATOM   6374 N N     . ALA C 3 333 ? 108.279 113.002 91.143  1.00 6.97   ? 328 ALA B N     1 
ATOM   6375 C CA    . ALA C 3 333 ? 109.285 113.144 92.180  1.00 6.97   ? 328 ALA B CA    1 
ATOM   6376 C C     . ALA C 3 333 ? 109.618 114.619 92.353  1.00 6.97   ? 328 ALA B C     1 
ATOM   6377 O O     . ALA C 3 333 ? 109.766 115.352 91.371  1.00 6.97   ? 328 ALA B O     1 
ATOM   6378 C CB    . ALA C 3 333 ? 110.546 112.353 91.835  1.00 6.97   ? 328 ALA B CB    1 
ATOM   6379 N N     . THR C 3 334 ? 109.700 115.056 93.609  1.00 7.06   ? 329 THR B N     1 
ATOM   6380 C CA    . THR C 3 334 ? 110.102 116.419 93.929  1.00 7.06   ? 329 THR B CA    1 
ATOM   6381 C C     . THR C 3 334 ? 111.177 116.368 95.000  1.00 7.06   ? 329 THR B C     1 
ATOM   6382 O O     . THR C 3 334 ? 111.004 115.697 96.020  1.00 7.06   ? 329 THR B O     1 
ATOM   6383 C CB    . THR C 3 334 ? 108.919 117.267 94.417  1.00 7.06   ? 329 THR B CB    1 
ATOM   6384 O OG1   . THR C 3 334 ? 108.611 116.928 95.774  1.00 7.06   ? 329 THR B OG1   1 
ATOM   6385 C CG2   . THR C 3 334 ? 107.693 117.038 93.548  1.00 7.06   ? 329 THR B CG2   1 
ATOM   6386 N N     . GLY C 3 335 ? 112.272 117.075 94.766  1.00 6.94   ? 330 GLY B N     1 
ATOM   6387 C CA    . GLY C 3 335 ? 113.368 117.149 95.720  1.00 6.94   ? 330 GLY B CA    1 
ATOM   6388 C C     . GLY C 3 335 ? 113.581 118.581 96.167  1.00 6.94   ? 330 GLY B C     1 
ATOM   6389 O O     . GLY C 3 335 ? 113.553 119.503 95.350  1.00 6.94   ? 330 GLY B O     1 
ATOM   6390 N N     . SER C 3 336 ? 113.814 118.755 97.465  1.00 7.95   ? 331 SER B N     1 
ATOM   6391 C CA    . SER C 3 336 ? 113.925 120.070 98.075  1.00 7.95   ? 331 SER B CA    1 
ATOM   6392 C C     . SER C 3 336 ? 115.203 120.158 98.896  1.00 7.95   ? 331 SER B C     1 
ATOM   6393 O O     . SER C 3 336 ? 115.923 119.173 99.086  1.00 7.95   ? 331 SER B O     1 
ATOM   6394 C CB    . SER C 3 336 ? 112.711 120.376 98.962  1.00 7.95   ? 331 SER B CB    1 
ATOM   6395 O OG    . SER C 3 336 ? 111.527 120.439 98.196  1.00 7.95   ? 331 SER B OG    1 
ATOM   6396 N N     . TRP C 3 337 ? 115.476 121.367 99.382  1.00 9.76   ? 332 TRP B N     1 
ATOM   6397 C CA    . TRP C 3 337 ? 116.597 121.620 100.275 1.00 9.76   ? 332 TRP B CA    1 
ATOM   6398 C C     . TRP C 3 337 ? 116.394 121.015 101.657 1.00 9.76   ? 332 TRP B C     1 
ATOM   6399 O O     . TRP C 3 337 ? 117.337 121.007 102.456 1.00 9.76   ? 332 TRP B O     1 
ATOM   6400 C CB    . TRP C 3 337 ? 116.831 123.129 100.399 1.00 9.76   ? 332 TRP B CB    1 
ATOM   6401 C CG    . TRP C 3 337 ? 117.292 123.789 99.128  1.00 9.76   ? 332 TRP B CG    1 
ATOM   6402 C CD1   . TRP C 3 337 ? 117.249 123.267 97.869  1.00 9.76   ? 332 TRP B CD1   1 
ATOM   6403 C CD2   . TRP C 3 337 ? 117.864 125.097 98.999  1.00 9.76   ? 332 TRP B CD2   1 
ATOM   6404 N NE1   . TRP C 3 337 ? 117.760 124.165 96.965  1.00 9.76   ? 332 TRP B NE1   1 
ATOM   6405 C CE2   . TRP C 3 337 ? 118.143 125.297 97.632  1.00 9.76   ? 332 TRP B CE2   1 
ATOM   6406 C CE3   . TRP C 3 337 ? 118.167 126.117 99.905  1.00 9.76   ? 332 TRP B CE3   1 
ATOM   6407 C CZ2   . TRP C 3 337 ? 118.713 126.474 97.151  1.00 9.76   ? 332 TRP B CZ2   1 
ATOM   6408 C CZ3   . TRP C 3 337 ? 118.731 127.285 99.424  1.00 9.76   ? 332 TRP B CZ3   1 
ATOM   6409 C CH2   . TRP C 3 337 ? 118.996 127.454 98.060  1.00 9.76   ? 332 TRP B CH2   1 
ATOM   6410 N N     . ASP C 3 338 ? 115.194 120.510 101.958 1.00 8.53   ? 333 ASP B N     1 
ATOM   6411 C CA    . ASP C 3 338 ? 114.944 119.889 103.253 1.00 8.53   ? 333 ASP B CA    1 
ATOM   6412 C C     . ASP C 3 338 ? 115.439 118.449 103.309 1.00 8.53   ? 333 ASP B C     1 
ATOM   6413 O O     . ASP C 3 338 ? 115.143 117.744 104.279 1.00 8.53   ? 333 ASP B O     1 
ATOM   6414 C CB    . ASP C 3 338 ? 113.450 119.942 103.579 1.00 8.53   ? 333 ASP B CB    1 
ATOM   6415 C CG    . ASP C 3 338 ? 112.622 119.059 102.671 1.00 8.53   ? 333 ASP B CG    1 
ATOM   6416 O OD1   . ASP C 3 338 ? 113.123 118.677 101.596 1.00 8.53   ? 333 ASP B OD1   1 
ATOM   6417 O OD2   . ASP C 3 338 ? 111.464 118.756 103.025 1.00 8.53   ? 333 ASP B OD2   1 
ATOM   6418 N N     . SER C 3 339 ? 116.164 117.997 102.282 1.00 7.48   ? 334 SER B N     1 
ATOM   6419 C CA    . SER C 3 339 ? 116.868 116.718 102.295 1.00 7.48   ? 334 SER B CA    1 
ATOM   6420 C C     . SER C 3 339 ? 115.938 115.530 102.089 1.00 7.48   ? 334 SER B C     1 
ATOM   6421 O O     . SER C 3 339 ? 116.292 114.400 102.440 1.00 7.48   ? 334 SER B O     1 
ATOM   6422 C CB    . SER C 3 339 ? 117.642 116.545 103.605 1.00 7.48   ? 334 SER B CB    1 
ATOM   6423 O OG    . SER C 3 339 ? 118.580 117.591 103.783 1.00 7.48   ? 334 SER B OG    1 
ATOM   6424 N N     . PHE C 3 340 ? 114.754 115.760 101.526 1.00 7.09   ? 335 PHE B N     1 
ATOM   6425 C CA    . PHE C 3 340 ? 113.812 114.682 101.260 1.00 7.09   ? 335 PHE B CA    1 
ATOM   6426 C C     . PHE C 3 340 ? 113.321 114.760 99.825  1.00 7.09   ? 335 PHE B C     1 
ATOM   6427 O O     . PHE C 3 340 ? 113.016 115.845 99.323  1.00 7.09   ? 335 PHE B O     1 
ATOM   6428 C CB    . PHE C 3 340 ? 112.603 114.736 102.205 1.00 7.09   ? 335 PHE B CB    1 
ATOM   6429 C CG    . PHE C 3 340 ? 112.964 114.657 103.656 1.00 7.09   ? 335 PHE B CG    1 
ATOM   6430 C CD1   . PHE C 3 340 ? 113.659 113.567 104.151 1.00 7.09   ? 335 PHE B CD1   1 
ATOM   6431 C CD2   . PHE C 3 340 ? 112.607 115.670 104.526 1.00 7.09   ? 335 PHE B CD2   1 
ATOM   6432 C CE1   . PHE C 3 340 ? 113.994 113.493 105.486 1.00 7.09   ? 335 PHE B CE1   1 
ATOM   6433 C CE2   . PHE C 3 340 ? 112.940 115.601 105.862 1.00 7.09   ? 335 PHE B CE2   1 
ATOM   6434 C CZ    . PHE C 3 340 ? 113.634 114.510 106.343 1.00 7.09   ? 335 PHE B CZ    1 
ATOM   6435 N N     . LEU C 3 341 ? 113.241 113.605 99.173  1.00 6.44   ? 336 LEU B N     1 
ATOM   6436 C CA    . LEU C 3 341 ? 112.498 113.461 97.933  1.00 6.44   ? 336 LEU B CA    1 
ATOM   6437 C C     . LEU C 3 341 ? 111.126 112.892 98.253  1.00 6.44   ? 336 LEU B C     1 
ATOM   6438 O O     . LEU C 3 341 ? 110.981 112.029 99.121  1.00 6.44   ? 336 LEU B O     1 
ATOM   6439 C CB    . LEU C 3 341 ? 113.205 112.542 96.933  1.00 6.44   ? 336 LEU B CB    1 
ATOM   6440 C CG    . LEU C 3 341 ? 114.509 113.039 96.316  1.00 6.44   ? 336 LEU B CG    1 
ATOM   6441 C CD1   . LEU C 3 341 ? 115.683 112.487 97.090  1.00 6.44   ? 336 LEU B CD1   1 
ATOM   6442 C CD2   . LEU C 3 341 ? 114.591 112.654 94.851  1.00 6.44   ? 336 LEU B CD2   1 
ATOM   6443 N N     . LYS C 3 342 ? 110.117 113.390 97.550  1.00 6.67   ? 337 LYS B N     1 
ATOM   6444 C CA    . LYS C 3 342 ? 108.752 112.936 97.756  1.00 6.67   ? 337 LYS B CA    1 
ATOM   6445 C C     . LYS C 3 342 ? 108.154 112.542 96.418  1.00 6.67   ? 337 LYS B C     1 
ATOM   6446 O O     . LYS C 3 342 ? 108.259 113.290 95.442  1.00 6.67   ? 337 LYS B O     1 
ATOM   6447 C CB    . LYS C 3 342 ? 107.902 114.018 98.430  1.00 6.67   ? 337 LYS B CB    1 
ATOM   6448 C CG    . LYS C 3 342 ? 108.071 114.061 99.939  1.00 6.67   ? 337 LYS B CG    1 
ATOM   6449 C CD    . LYS C 3 342 ? 107.468 115.313 100.542 1.00 6.67   ? 337 LYS B CD    1 
ATOM   6450 C CE    . LYS C 3 342 ? 107.400 115.220 102.057 1.00 6.67   ? 337 LYS B CE    1 
ATOM   6451 N NZ    . LYS C 3 342 ? 106.035 114.856 102.531 1.00 6.67   ? 337 LYS B NZ    1 
ATOM   6452 N N     . ILE C 3 343 ? 107.547 111.360 96.379  1.00 7.09   ? 338 ILE B N     1 
ATOM   6453 C CA    . ILE C 3 343 ? 106.834 110.869 95.208  1.00 7.09   ? 338 ILE B CA    1 
ATOM   6454 C C     . ILE C 3 343 ? 105.349 111.105 95.430  1.00 7.09   ? 338 ILE B C     1 
ATOM   6455 O O     . ILE C 3 343 ? 104.802 110.739 96.476  1.00 7.09   ? 338 ILE B O     1 
ATOM   6456 C CB    . ILE C 3 343 ? 107.136 109.383 94.946  1.00 7.09   ? 338 ILE B CB    1 
ATOM   6457 C CG1   . ILE C 3 343 ? 108.623 109.189 94.636  1.00 7.09   ? 338 ILE B CG1   1 
ATOM   6458 C CG2   . ILE C 3 343 ? 106.299 108.866 93.791  1.00 7.09   ? 338 ILE B CG2   1 
ATOM   6459 C CD1   . ILE C 3 343 ? 109.487 108.956 95.844  1.00 7.09   ? 338 ILE B CD1   1 
ATOM   6460 N N     . TRP C 3 344 ? 104.706 111.727 94.450  1.00 7.44   ? 339 TRP B N     1 
ATOM   6461 C CA    . TRP C 3 344 ? 103.324 112.164 94.543  1.00 7.44   ? 339 TRP B CA    1 
ATOM   6462 C C     . TRP C 3 344 ? 102.525 111.526 93.419  1.00 7.44   ? 339 TRP B C     1 
ATOM   6463 O O     . TRP C 3 344 ? 103.013 111.402 92.290  1.00 7.44   ? 339 TRP B O     1 
ATOM   6464 C CB    . TRP C 3 344 ? 103.217 113.693 94.450  1.00 7.44   ? 339 TRP B CB    1 
ATOM   6465 C CG    . TRP C 3 344 ? 104.184 114.437 95.328  1.00 7.44   ? 339 TRP B CG    1 
ATOM   6466 C CD1   . TRP C 3 344 ? 105.539 114.496 95.189  1.00 7.44   ? 339 TRP B CD1   1 
ATOM   6467 C CD2   . TRP C 3 344 ? 103.865 115.239 96.471  1.00 7.44   ? 339 TRP B CD2   1 
ATOM   6468 N NE1   . TRP C 3 344 ? 106.085 115.276 96.176  1.00 7.44   ? 339 TRP B NE1   1 
ATOM   6469 C CE2   . TRP C 3 344 ? 105.078 115.745 96.977  1.00 7.44   ? 339 TRP B CE2   1 
ATOM   6470 C CE3   . TRP C 3 344 ? 102.672 115.576 97.118  1.00 7.44   ? 339 TRP B CE3   1 
ATOM   6471 C CZ2   . TRP C 3 344 ? 105.134 116.570 98.098  1.00 7.44   ? 339 TRP B CZ2   1 
ATOM   6472 C CZ3   . TRP C 3 344 ? 102.730 116.394 98.230  1.00 7.44   ? 339 TRP B CZ3   1 
ATOM   6473 C CH2   . TRP C 3 344 ? 103.952 116.881 98.709  1.00 7.44   ? 339 TRP B CH2   1 
ATOM   6474 N N     . ASN C 3 345 ? 101.299 111.124 93.733  1.00 11.67  ? 340 ASN B N     1 
ATOM   6475 C CA    . ASN C 3 345 ? 100.424 110.500 92.753  1.00 11.67  ? 340 ASN B CA    1 
ATOM   6476 C C     . ASN C 3 345 ? 98.969  110.816 93.070  1.00 11.67  ? 340 ASN B C     1 
ATOM   6477 O O     . ASN C 3 345 ? 98.105  110.785 92.194  1.00 11.67  ? 340 ASN B O     1 
ATOM   6478 C CB    . ASN C 3 345 ? 100.644 108.988 92.725  1.00 11.67  ? 340 ASN B CB    1 
ATOM   6479 C CG    . ASN C 3 345 ? 100.026 108.333 91.508  1.00 11.67  ? 340 ASN B CG    1 
ATOM   6480 O OD1   . ASN C 3 345 ? 99.321  108.978 90.733  1.00 11.67  ? 340 ASN B OD1   1 
ATOM   6481 N ND2   . ASN C 3 345 ? 100.293 107.045 91.331  1.00 11.67  ? 340 ASN B ND2   1 
ATOM   6482 N N     . ILE D 2 9   ? 136.410 144.127 62.299  1.00 108.27 ? 9   ILE G N     1 
ATOM   6483 C CA    . ILE D 2 9   ? 135.119 144.384 61.602  1.00 108.27 ? 9   ILE G CA    1 
ATOM   6484 C C     . ILE D 2 9   ? 134.281 143.111 61.573  1.00 108.27 ? 9   ILE G C     1 
ATOM   6485 O O     . ILE D 2 9   ? 133.051 143.167 61.538  1.00 108.27 ? 9   ILE G O     1 
ATOM   6486 C CB    . ILE D 2 9   ? 135.354 144.919 60.175  1.00 108.27 ? 9   ILE G CB    1 
ATOM   6487 C CG1   . ILE D 2 9   ? 134.073 145.545 59.617  1.00 108.27 ? 9   ILE G CG1   1 
ATOM   6488 C CG2   . ILE D 2 9   ? 135.837 143.805 59.258  1.00 108.27 ? 9   ILE G CG2   1 
ATOM   6489 C CD1   . ILE D 2 9   ? 133.692 146.857 60.273  1.00 108.27 ? 9   ILE G CD1   1 
ATOM   6490 N N     . ALA D 2 10  ? 134.954 141.958 61.587  1.00 108.68 ? 10  ALA G N     1 
ATOM   6491 C CA    . ALA D 2 10  ? 134.257 140.679 61.559  1.00 108.68 ? 10  ALA G CA    1 
ATOM   6492 C C     . ALA D 2 10  ? 133.602 140.337 62.891  1.00 108.68 ? 10  ALA G C     1 
ATOM   6493 O O     . ALA D 2 10  ? 132.688 139.503 62.921  1.00 108.68 ? 10  ALA G O     1 
ATOM   6494 C CB    . ALA D 2 10  ? 135.225 139.563 61.163  1.00 108.68 ? 10  ALA G CB    1 
ATOM   6495 N N     . GLN D 2 11  ? 134.039 140.970 63.983  1.00 108.30 ? 11  GLN G N     1 
ATOM   6496 C CA    . GLN D 2 11  ? 133.499 140.644 65.299  1.00 108.30 ? 11  GLN G CA    1 
ATOM   6497 C C     . GLN D 2 11  ? 131.994 140.869 65.342  1.00 108.30 ? 11  GLN G C     1 
ATOM   6498 O O     . GLN D 2 11  ? 131.242 140.030 65.851  1.00 108.30 ? 11  GLN G O     1 
ATOM   6499 C CB    . GLN D 2 11  ? 134.206 141.478 66.369  1.00 108.30 ? 11  GLN G CB    1 
ATOM   6500 C CG    . GLN D 2 11  ? 133.839 141.107 67.800  1.00 108.30 ? 11  GLN G CG    1 
ATOM   6501 C CD    . GLN D 2 11  ? 132.597 141.825 68.298  1.00 108.30 ? 11  GLN G CD    1 
ATOM   6502 O OE1   . GLN D 2 11  ? 132.131 142.786 67.686  1.00 108.30 ? 11  GLN G OE1   1 
ATOM   6503 N NE2   . GLN D 2 11  ? 132.057 141.360 69.419  1.00 108.30 ? 11  GLN G NE2   1 
ATOM   6504 N N     . ALA D 2 12  ? 131.534 142.006 64.817  1.00 106.33 ? 12  ALA G N     1 
ATOM   6505 C CA    . ALA D 2 12  ? 130.103 142.250 64.698  1.00 106.33 ? 12  ALA G CA    1 
ATOM   6506 C C     . ALA D 2 12  ? 129.518 141.647 63.428  1.00 106.33 ? 12  ALA G C     1 
ATOM   6507 O O     . ALA D 2 12  ? 128.299 141.451 63.354  1.00 106.33 ? 12  ALA G O     1 
ATOM   6508 C CB    . ALA D 2 12  ? 129.821 143.753 64.731  1.00 106.33 ? 12  ALA G CB    1 
ATOM   6509 N N     . ARG D 2 13  ? 130.356 141.349 62.432  1.00 105.04 ? 13  ARG G N     1 
ATOM   6510 C CA    . ARG D 2 13  ? 129.855 140.715 61.218  1.00 105.04 ? 13  ARG G CA    1 
ATOM   6511 C C     . ARG D 2 13  ? 129.277 139.342 61.530  1.00 105.04 ? 13  ARG G C     1 
ATOM   6512 O O     . ARG D 2 13  ? 128.211 138.977 61.022  1.00 105.04 ? 13  ARG G O     1 
ATOM   6513 C CB    . ARG D 2 13  ? 130.970 140.606 60.179  1.00 105.04 ? 13  ARG G CB    1 
ATOM   6514 C CG    . ARG D 2 13  ? 130.497 140.202 58.780  1.00 105.04 ? 13  ARG G CG    1 
ATOM   6515 C CD    . ARG D 2 13  ? 130.301 138.696 58.606  1.00 105.04 ? 13  ARG G CD    1 
ATOM   6516 N NE    . ARG D 2 13  ? 131.371 137.906 59.205  1.00 105.04 ? 13  ARG G NE    1 
ATOM   6517 C CZ    . ARG D 2 13  ? 131.268 136.622 59.521  1.00 105.04 ? 13  ARG G CZ    1 
ATOM   6518 N NH1   . ARG D 2 13  ? 130.154 135.941 59.304  1.00 105.04 ? 13  ARG G NH1   1 
ATOM   6519 N NH2   . ARG D 2 13  ? 132.311 136.003 60.068  1.00 105.04 ? 13  ARG G NH2   1 
ATOM   6520 N N     . LYS D 2 14  ? 129.962 138.565 62.374  1.00 104.79 ? 14  LYS G N     1 
ATOM   6521 C CA    . LYS D 2 14  ? 129.426 137.260 62.745  1.00 104.79 ? 14  LYS G CA    1 
ATOM   6522 C C     . LYS D 2 14  ? 128.146 137.394 63.563  1.00 104.79 ? 14  LYS G C     1 
ATOM   6523 O O     . LYS D 2 14  ? 127.230 136.578 63.416  1.00 104.79 ? 14  LYS G O     1 
ATOM   6524 C CB    . LYS D 2 14  ? 130.475 136.451 63.511  1.00 104.79 ? 14  LYS G CB    1 
ATOM   6525 C CG    . LYS D 2 14  ? 130.817 136.981 64.893  1.00 104.79 ? 14  LYS G CG    1 
ATOM   6526 C CD    . LYS D 2 14  ? 131.799 136.059 65.600  1.00 104.79 ? 14  LYS G CD    1 
ATOM   6527 C CE    . LYS D 2 14  ? 132.099 136.532 67.013  1.00 104.79 ? 14  LYS G CE    1 
ATOM   6528 N NZ    . LYS D 2 14  ? 132.871 137.803 67.025  1.00 104.79 ? 14  LYS G NZ    1 
ATOM   6529 N N     . LEU D 2 15  ? 128.058 138.413 64.420  1.00 101.90 ? 15  LEU G N     1 
ATOM   6530 C CA    . LEU D 2 15  ? 126.835 138.626 65.190  1.00 101.90 ? 15  LEU G CA    1 
ATOM   6531 C C     . LEU D 2 15  ? 125.659 138.940 64.271  1.00 101.90 ? 15  LEU G C     1 
ATOM   6532 O O     . LEU D 2 15  ? 124.563 138.388 64.430  1.00 101.90 ? 15  LEU G O     1 
ATOM   6533 C CB    . LEU D 2 15  ? 127.049 139.755 66.200  1.00 101.90 ? 15  LEU G CB    1 
ATOM   6534 C CG    . LEU D 2 15  ? 125.881 140.069 67.138  1.00 101.90 ? 15  LEU G CG    1 
ATOM   6535 C CD1   . LEU D 2 15  ? 125.619 138.908 68.084  1.00 101.90 ? 15  LEU G CD1   1 
ATOM   6536 C CD2   . LEU D 2 15  ? 126.154 141.347 67.918  1.00 101.90 ? 15  LEU G CD2   1 
ATOM   6537 N N     . VAL D 2 16  ? 125.871 139.825 63.294  1.00 101.36 ? 16  VAL G N     1 
ATOM   6538 C CA    . VAL D 2 16  ? 124.789 140.149 62.368  1.00 101.36 ? 16  VAL G CA    1 
ATOM   6539 C C     . VAL D 2 16  ? 124.457 138.946 61.495  1.00 101.36 ? 16  VAL G C     1 
ATOM   6540 O O     . VAL D 2 16  ? 123.298 138.754 61.111  1.00 101.36 ? 16  VAL G O     1 
ATOM   6541 C CB    . VAL D 2 16  ? 125.136 141.387 61.519  1.00 101.36 ? 16  VAL G CB    1 
ATOM   6542 C CG1   . VAL D 2 16  ? 125.303 142.604 62.412  1.00 101.36 ? 16  VAL G CG1   1 
ATOM   6543 C CG2   . VAL D 2 16  ? 126.383 141.153 60.698  1.00 101.36 ? 16  VAL G CG2   1 
ATOM   6544 N N     . GLU D 2 17  ? 125.451 138.120 61.161  1.00 100.09 ? 17  GLU G N     1 
ATOM   6545 C CA    . GLU D 2 17  ? 125.165 136.893 60.423  1.00 100.09 ? 17  GLU G CA    1 
ATOM   6546 C C     . GLU D 2 17  ? 124.298 135.950 61.249  1.00 100.09 ? 17  GLU G C     1 
ATOM   6547 O O     . GLU D 2 17  ? 123.393 135.299 60.717  1.00 100.09 ? 17  GLU G O     1 
ATOM   6548 C CB    . GLU D 2 17  ? 126.470 136.209 60.017  1.00 100.09 ? 17  GLU G CB    1 
ATOM   6549 C CG    . GLU D 2 17  ? 126.287 135.060 59.033  1.00 100.09 ? 17  GLU G CG    1 
ATOM   6550 C CD    . GLU D 2 17  ? 126.106 133.715 59.715  1.00 100.09 ? 17  GLU G CD    1 
ATOM   6551 O OE1   . GLU D 2 17  ? 126.023 133.676 60.961  1.00 100.09 ? 17  GLU G OE1   1 
ATOM   6552 O OE2   . GLU D 2 17  ? 126.047 132.692 59.000  1.00 100.09 ? 17  GLU G OE2   1 
ATOM   6553 N N     . GLN D 2 18  ? 124.569 135.856 62.552  1.00 96.63  ? 18  GLN G N     1 
ATOM   6554 C CA    . GLN D 2 18  ? 123.722 135.050 63.426  1.00 96.63  ? 18  GLN G CA    1 
ATOM   6555 C C     . GLN D 2 18  ? 122.302 135.602 63.472  1.00 96.63  ? 18  GLN G C     1 
ATOM   6556 O O     . GLN D 2 18  ? 121.329 134.838 63.449  1.00 96.63  ? 18  GLN G O     1 
ATOM   6557 C CB    . GLN D 2 18  ? 124.319 134.994 64.832  1.00 96.63  ? 18  GLN G CB    1 
ATOM   6558 C CG    . GLN D 2 18  ? 125.524 134.075 64.958  1.00 96.63  ? 18  GLN G CG    1 
ATOM   6559 C CD    . GLN D 2 18  ? 126.516 134.553 66.000  1.00 96.63  ? 18  GLN G CD    1 
ATOM   6560 O OE1   . GLN D 2 18  ? 126.131 135.052 67.057  1.00 96.63  ? 18  GLN G OE1   1 
ATOM   6561 N NE2   . GLN D 2 18  ? 127.802 134.401 65.706  1.00 96.63  ? 18  GLN G NE2   1 
ATOM   6562 N N     . LEU D 2 19  ? 122.164 136.928 63.539  1.00 94.31  ? 19  LEU G N     1 
ATOM   6563 C CA    . LEU D 2 19  ? 120.831 137.526 63.496  1.00 94.31  ? 19  LEU G CA    1 
ATOM   6564 C C     . LEU D 2 19  ? 120.123 137.193 62.187  1.00 94.31  ? 19  LEU G C     1 
ATOM   6565 O O     . LEU D 2 19  ? 118.929 136.872 62.181  1.00 94.31  ? 19  LEU G O     1 
ATOM   6566 C CB    . LEU D 2 19  ? 120.919 139.040 63.685  1.00 94.31  ? 19  LEU G CB    1 
ATOM   6567 C CG    . LEU D 2 19  ? 121.587 139.535 64.968  1.00 94.31  ? 19  LEU G CG    1 
ATOM   6568 C CD1   . LEU D 2 19  ? 121.733 141.049 64.945  1.00 94.31  ? 19  LEU G CD1   1 
ATOM   6569 C CD2   . LEU D 2 19  ? 120.798 139.089 66.189  1.00 94.31  ? 19  LEU G CD2   1 
ATOM   6570 N N     . LYS D 2 20  ? 120.843 137.267 61.067  1.00 94.54  ? 20  LYS G N     1 
ATOM   6571 C CA    . LYS D 2 20  ? 120.247 136.933 59.777  1.00 94.54  ? 20  LYS G CA    1 
ATOM   6572 C C     . LYS D 2 20  ? 119.811 135.474 59.735  1.00 94.54  ? 20  LYS G C     1 
ATOM   6573 O O     . LYS D 2 20  ? 118.739 135.155 59.208  1.00 94.54  ? 20  LYS G O     1 
ATOM   6574 C CB    . LYS D 2 20  ? 121.238 137.225 58.651  1.00 94.54  ? 20  LYS G CB    1 
ATOM   6575 C CG    . LYS D 2 20  ? 121.462 138.706 58.389  1.00 94.54  ? 20  LYS G CG    1 
ATOM   6576 C CD    . LYS D 2 20  ? 122.291 138.929 57.134  1.00 94.54  ? 20  LYS G CD    1 
ATOM   6577 C CE    . LYS D 2 20  ? 123.744 138.534 57.347  1.00 94.54  ? 20  LYS G CE    1 
ATOM   6578 N NZ    . LYS D 2 20  ? 124.571 138.767 56.131  1.00 94.54  ? 20  LYS G NZ    1 
ATOM   6579 N N     . MET D 2 21  ? 120.631 134.575 60.280  1.00 87.50  ? 21  MET G N     1 
ATOM   6580 C CA    . MET D 2 21  ? 120.245 133.170 60.355  1.00 87.50  ? 21  MET G CA    1 
ATOM   6581 C C     . MET D 2 21  ? 118.976 133.007 61.180  1.00 87.50  ? 21  MET G C     1 
ATOM   6582 O O     . MET D 2 21  ? 118.071 132.250 60.810  1.00 87.50  ? 21  MET G O     1 
ATOM   6583 C CB    . MET D 2 21  ? 121.386 132.346 60.953  1.00 87.50  ? 21  MET G CB    1 
ATOM   6584 C CG    . MET D 2 21  ? 122.597 132.208 60.044  1.00 87.50  ? 21  MET G CG    1 
ATOM   6585 S SD    . MET D 2 21  ? 122.258 131.239 58.562  1.00 87.50  ? 21  MET G SD    1 
ATOM   6586 C CE    . MET D 2 21  ? 122.097 129.597 59.261  1.00 87.50  ? 21  MET G CE    1 
ATOM   6587 N N     . GLU D 2 22  ? 118.892 133.715 62.308  1.00 78.42  ? 22  GLU G N     1 
ATOM   6588 C CA    . GLU D 2 22  ? 117.667 133.708 63.099  1.00 78.42  ? 22  GLU G CA    1 
ATOM   6589 C C     . GLU D 2 22  ? 116.493 134.306 62.336  1.00 78.42  ? 22  GLU G C     1 
ATOM   6590 O O     . GLU D 2 22  ? 115.339 134.005 62.660  1.00 78.42  ? 22  GLU G O     1 
ATOM   6591 C CB    . GLU D 2 22  ? 117.877 134.478 64.404  1.00 78.42  ? 22  GLU G CB    1 
ATOM   6592 C CG    . GLU D 2 22  ? 118.842 133.814 65.373  1.00 78.42  ? 22  GLU G CG    1 
ATOM   6593 C CD    . GLU D 2 22  ? 119.336 134.763 66.450  1.00 78.42  ? 22  GLU G CD    1 
ATOM   6594 O OE1   . GLU D 2 22  ? 118.951 135.951 66.422  1.00 78.42  ? 22  GLU G OE1   1 
ATOM   6595 O OE2   . GLU D 2 22  ? 120.110 134.320 67.325  1.00 78.42  ? 22  GLU G OE2   1 
ATOM   6596 N N     . ALA D 2 23  ? 116.760 135.145 61.334  1.00 83.21  ? 23  ALA G N     1 
ATOM   6597 C CA    . ALA D 2 23  ? 115.687 135.808 60.601  1.00 83.21  ? 23  ALA G CA    1 
ATOM   6598 C C     . ALA D 2 23  ? 115.006 134.860 59.621  1.00 83.21  ? 23  ALA G C     1 
ATOM   6599 O O     . ALA D 2 23  ? 113.780 134.707 59.645  1.00 83.21  ? 23  ALA G O     1 
ATOM   6600 C CB    . ALA D 2 23  ? 116.238 137.029 59.863  1.00 83.21  ? 23  ALA G CB    1 
ATOM   6601 N N     . ASN D 2 24  ? 115.784 134.214 58.751  1.00 78.88  ? 24  ASN G N     1 
ATOM   6602 C CA    . ASN D 2 24  ? 115.233 133.358 57.700  1.00 78.88  ? 24  ASN G CA    1 
ATOM   6603 C C     . ASN D 2 24  ? 114.760 132.051 58.332  1.00 78.88  ? 24  ASN G C     1 
ATOM   6604 O O     . ASN D 2 24  ? 115.468 131.041 58.373  1.00 78.88  ? 24  ASN G O     1 
ATOM   6605 C CB    . ASN D 2 24  ? 116.267 133.113 56.609  1.00 78.88  ? 24  ASN G CB    1 
ATOM   6606 C CG    . ASN D 2 24  ? 115.715 132.298 55.456  1.00 78.88  ? 24  ASN G CG    1 
ATOM   6607 O OD1   . ASN D 2 24  ? 114.506 132.094 55.347  1.00 78.88  ? 24  ASN G OD1   1 
ATOM   6608 N ND2   . ASN D 2 24  ? 116.602 131.826 54.587  1.00 78.88  ? 24  ASN G ND2   1 
ATOM   6609 N N     . ILE D 2 25  ? 113.527 132.080 58.832  1.00 68.64  ? 25  ILE G N     1 
ATOM   6610 C CA    . ILE D 2 25  ? 112.905 130.939 59.492  1.00 68.64  ? 25  ILE G CA    1 
ATOM   6611 C C     . ILE D 2 25  ? 111.499 130.766 58.937  1.00 68.64  ? 25  ILE G C     1 
ATOM   6612 O O     . ILE D 2 25  ? 110.815 131.750 58.635  1.00 68.64  ? 25  ILE G O     1 
ATOM   6613 C CB    . ILE D 2 25  ? 112.859 131.121 61.024  1.00 68.64  ? 25  ILE G CB    1 
ATOM   6614 C CG1   . ILE D 2 25  ? 114.252 131.440 61.577  1.00 68.64  ? 25  ILE G CG1   1 
ATOM   6615 C CG2   . ILE D 2 25  ? 112.290 129.877 61.691  1.00 68.64  ? 25  ILE G CG2   1 
ATOM   6616 C CD1   . ILE D 2 25  ? 115.249 130.308 61.440  1.00 68.64  ? 25  ILE G CD1   1 
ATOM   6617 N N     . ASP D 2 26  ? 111.068 129.511 58.801  1.00 69.22  ? 26  ASP G N     1 
ATOM   6618 C CA    . ASP D 2 26  ? 109.701 129.203 58.381  1.00 69.22  ? 26  ASP G CA    1 
ATOM   6619 C C     . ASP D 2 26  ? 108.778 129.485 59.563  1.00 69.22  ? 26  ASP G C     1 
ATOM   6620 O O     . ASP D 2 26  ? 108.429 128.606 60.354  1.00 69.22  ? 26  ASP G O     1 
ATOM   6621 C CB    . ASP D 2 26  ? 109.579 127.758 57.909  1.00 69.22  ? 26  ASP G CB    1 
ATOM   6622 C CG    . ASP D 2 26  ? 110.209 126.771 58.874  1.00 69.22  ? 26  ASP G CG    1 
ATOM   6623 O OD1   . ASP D 2 26  ? 110.958 127.211 59.772  1.00 69.22  ? 26  ASP G OD1   1 
ATOM   6624 O OD2   . ASP D 2 26  ? 109.949 125.557 58.737  1.00 69.22  ? 26  ASP G OD2   1 
ATOM   6625 N N     . ARG D 2 27  ? 108.378 130.748 59.679  1.00 66.88  ? 27  ARG G N     1 
ATOM   6626 C CA    . ARG D 2 27  ? 107.612 131.210 60.832  1.00 66.88  ? 27  ARG G CA    1 
ATOM   6627 C C     . ARG D 2 27  ? 106.190 130.666 60.764  1.00 66.88  ? 27  ARG G C     1 
ATOM   6628 O O     . ARG D 2 27  ? 105.482 130.869 59.773  1.00 66.88  ? 27  ARG G O     1 
ATOM   6629 C CB    . ARG D 2 27  ? 107.619 132.734 60.875  1.00 66.88  ? 27  ARG G CB    1 
ATOM   6630 C CG    . ARG D 2 27  ? 107.224 133.325 62.215  1.00 66.88  ? 27  ARG G CG    1 
ATOM   6631 C CD    . ARG D 2 27  ? 107.509 134.815 62.245  1.00 66.88  ? 27  ARG G CD    1 
ATOM   6632 N NE    . ARG D 2 27  ? 106.786 135.524 61.196  1.00 66.88  ? 27  ARG G NE    1 
ATOM   6633 C CZ    . ARG D 2 27  ? 107.176 136.672 60.657  1.00 66.88  ? 27  ARG G CZ    1 
ATOM   6634 N NH1   . ARG D 2 27  ? 108.275 137.289 61.061  1.00 66.88  ? 27  ARG G NH1   1 
ATOM   6635 N NH2   . ARG D 2 27  ? 106.447 137.212 59.686  1.00 66.88  ? 27  ARG G NH2   1 
ATOM   6636 N N     . ILE D 2 28  ? 105.776 129.972 61.819  1.00 57.99  ? 28  ILE G N     1 
ATOM   6637 C CA    . ILE D 2 28  ? 104.443 129.392 61.926  1.00 57.99  ? 28  ILE G CA    1 
ATOM   6638 C C     . ILE D 2 28  ? 103.690 130.182 62.989  1.00 57.99  ? 28  ILE G C     1 
ATOM   6639 O O     . ILE D 2 28  ? 104.089 130.202 64.157  1.00 57.99  ? 28  ILE G O     1 
ATOM   6640 C CB    . ILE D 2 28  ? 104.507 127.898 62.270  1.00 57.99  ? 28  ILE G CB    1 
ATOM   6641 C CG1   . ILE D 2 28  ? 104.981 127.098 61.053  1.00 57.99  ? 28  ILE G CG1   1 
ATOM   6642 C CG2   . ILE D 2 28  ? 103.151 127.395 62.745  1.00 57.99  ? 28  ILE G CG2   1 
ATOM   6643 C CD1   . ILE D 2 28  ? 105.688 125.808 61.405  1.00 57.99  ? 28  ILE G CD1   1 
ATOM   6644 N N     . LYS D 2 29  ? 102.592 130.825 62.587  1.00 59.90  ? 29  LYS G N     1 
ATOM   6645 C CA    . LYS D 2 29  ? 101.865 131.745 63.456  1.00 59.90  ? 29  LYS G CA    1 
ATOM   6646 C C     . LYS D 2 29  ? 101.608 131.145 64.834  1.00 59.90  ? 29  LYS G C     1 
ATOM   6647 O O     . LYS D 2 29  ? 101.462 129.927 64.975  1.00 59.90  ? 29  LYS G O     1 
ATOM   6648 C CB    . LYS D 2 29  ? 100.543 132.160 62.807  1.00 59.90  ? 29  LYS G CB    1 
ATOM   6649 C CG    . LYS D 2 29  ? 100.672 132.549 61.340  1.00 59.90  ? 29  LYS G CG    1 
ATOM   6650 C CD    . LYS D 2 29  ? 99.636  133.584 60.933  1.00 59.90  ? 29  LYS G CD    1 
ATOM   6651 C CE    . LYS D 2 29  ? 100.060 134.326 59.676  1.00 59.90  ? 29  LYS G CE    1 
ATOM   6652 N NZ    . LYS D 2 29  ? 99.202  135.513 59.409  1.00 59.90  ? 29  LYS G NZ    1 
ATOM   6653 N N     . VAL D 2 30  ? 101.556 132.004 65.856  1.00 54.81  ? 30  VAL G N     1 
ATOM   6654 C CA    . VAL D 2 30  ? 101.441 131.527 67.233  1.00 54.81  ? 30  VAL G CA    1 
ATOM   6655 C C     . VAL D 2 30  ? 100.152 130.738 67.427  1.00 54.81  ? 30  VAL G C     1 
ATOM   6656 O O     . VAL D 2 30  ? 100.144 129.688 68.081  1.00 54.81  ? 30  VAL G O     1 
ATOM   6657 C CB    . VAL D 2 30  ? 101.540 132.706 68.221  1.00 54.81  ? 30  VAL G CB    1 
ATOM   6658 C CG1   . VAL D 2 30  ? 102.957 133.258 68.249  1.00 54.81  ? 30  VAL G CG1   1 
ATOM   6659 C CG2   . VAL D 2 30  ? 100.544 133.807 67.870  1.00 54.81  ? 30  VAL G CG2   1 
ATOM   6660 N N     . SER D 2 31  ? 99.040  131.227 66.871  1.00 56.13  ? 31  SER G N     1 
ATOM   6661 C CA    . SER D 2 31  ? 97.769  130.531 67.049  1.00 56.13  ? 31  SER G CA    1 
ATOM   6662 C C     . SER D 2 31  ? 97.838  129.115 66.494  1.00 56.13  ? 31  SER G C     1 
ATOM   6663 O O     . SER D 2 31  ? 97.196  128.200 67.025  1.00 56.13  ? 31  SER G O     1 
ATOM   6664 C CB    . SER D 2 31  ? 96.640  131.313 66.379  1.00 56.13  ? 31  SER G CB    1 
ATOM   6665 O OG    . SER D 2 31  ? 95.407  130.625 66.496  1.00 56.13  ? 31  SER G OG    1 
ATOM   6666 N N     . LYS D 2 32  ? 98.604  128.915 65.421  1.00 55.99  ? 32  LYS G N     1 
ATOM   6667 C CA    . LYS D 2 32  ? 98.822  127.565 64.912  1.00 55.99  ? 32  LYS G CA    1 
ATOM   6668 C C     . LYS D 2 32  ? 99.584  126.721 65.926  1.00 55.99  ? 32  LYS G C     1 
ATOM   6669 O O     . LYS D 2 32  ? 99.280  125.539 66.124  1.00 55.99  ? 32  LYS G O     1 
ATOM   6670 C CB    . LYS D 2 32  ? 99.573  127.626 63.581  1.00 55.99  ? 32  LYS G CB    1 
ATOM   6671 C CG    . LYS D 2 32  ? 98.820  128.359 62.477  1.00 55.99  ? 32  LYS G CG    1 
ATOM   6672 C CD    . LYS D 2 32  ? 99.767  128.971 61.456  1.00 55.99  ? 32  LYS G CD    1 
ATOM   6673 C CE    . LYS D 2 32  ? 100.308 127.927 60.493  1.00 55.99  ? 32  LYS G CE    1 
ATOM   6674 N NZ    . LYS D 2 32  ? 101.507 128.417 59.755  1.00 55.99  ? 32  LYS G NZ    1 
ATOM   6675 N N     . ALA D 2 33  ? 100.585 127.316 66.581  1.00 50.01  ? 33  ALA G N     1 
ATOM   6676 C CA    . ALA D 2 33  ? 101.359 126.580 67.575  1.00 50.01  ? 33  ALA G CA    1 
ATOM   6677 C C     . ALA D 2 33  ? 100.496 126.177 68.763  1.00 50.01  ? 33  ALA G C     1 
ATOM   6678 O O     . ALA D 2 33  ? 100.615 125.059 69.277  1.00 50.01  ? 33  ALA G O     1 
ATOM   6679 C CB    . ALA D 2 33  ? 102.546 127.422 68.041  1.00 50.01  ? 33  ALA G CB    1 
ATOM   6680 N N     . ALA D 2 34  ? 99.622  127.078 69.219  1.00 47.91  ? 34  ALA G N     1 
ATOM   6681 C CA    . ALA D 2 34  ? 98.770  126.771 70.363  1.00 47.91  ? 34  ALA G CA    1 
ATOM   6682 C C     . ALA D 2 34  ? 97.857  125.588 70.065  1.00 47.91  ? 34  ALA G C     1 
ATOM   6683 O O     . ALA D 2 34  ? 97.666  124.705 70.909  1.00 47.91  ? 34  ALA G O     1 
ATOM   6684 C CB    . ALA D 2 34  ? 97.949  128.002 70.745  1.00 47.91  ? 34  ALA G CB    1 
ATOM   6685 N N     . ALA D 2 35  ? 97.282  125.557 68.861  1.00 50.13  ? 35  ALA G N     1 
ATOM   6686 C CA    . ALA D 2 35  ? 96.380  124.470 68.498  1.00 50.13  ? 35  ALA G CA    1 
ATOM   6687 C C     . ALA D 2 35  ? 97.103  123.130 68.519  1.00 50.13  ? 35  ALA G C     1 
ATOM   6688 O O     . ALA D 2 35  ? 96.533  122.110 68.923  1.00 50.13  ? 35  ALA G O     1 
ATOM   6689 C CB    . ALA D 2 35  ? 95.773  124.733 67.121  1.00 50.13  ? 35  ALA G CB    1 
ATOM   6690 N N     . ASP D 2 36  ? 98.360  123.109 68.071  1.00 46.87  ? 36  ASP G N     1 
ATOM   6691 C CA    . ASP D 2 36  ? 99.111  121.858 68.054  1.00 46.87  ? 36  ASP G CA    1 
ATOM   6692 C C     . ASP D 2 36  ? 99.326  121.325 69.465  1.00 46.87  ? 36  ASP G C     1 
ATOM   6693 O O     . ASP D 2 36  ? 99.136  120.129 69.721  1.00 46.87  ? 36  ASP G O     1 
ATOM   6694 C CB    . ASP D 2 36  ? 100.450 122.065 67.346  1.00 46.87  ? 36  ASP G CB    1 
ATOM   6695 C CG    . ASP D 2 36  ? 101.106 120.757 66.945  1.00 46.87  ? 36  ASP G CG    1 
ATOM   6696 O OD1   . ASP D 2 36  ? 100.542 119.686 67.253  1.00 46.87  ? 36  ASP G OD1   1 
ATOM   6697 O OD2   . ASP D 2 36  ? 102.183 120.802 66.314  1.00 46.87  ? 36  ASP G OD2   1 
ATOM   6698 N N     . LEU D 2 37  ? 99.719  122.197 70.397  1.00 39.68  ? 37  LEU G N     1 
ATOM   6699 C CA    . LEU D 2 37  ? 99.896  121.765 71.779  1.00 39.68  ? 37  LEU G CA    1 
ATOM   6700 C C     . LEU D 2 37  ? 98.573  121.319 72.387  1.00 39.68  ? 37  LEU G C     1 
ATOM   6701 O O     . LEU D 2 37  ? 98.524  120.329 73.126  1.00 39.68  ? 37  LEU G O     1 
ATOM   6702 C CB    . LEU D 2 37  ? 100.512 122.891 72.609  1.00 39.68  ? 37  LEU G CB    1 
ATOM   6703 C CG    . LEU D 2 37  ? 102.036 122.999 72.551  1.00 39.68  ? 37  LEU G CG    1 
ATOM   6704 C CD1   . LEU D 2 37  ? 102.476 123.669 71.260  1.00 39.68  ? 37  LEU G CD1   1 
ATOM   6705 C CD2   . LEU D 2 37  ? 102.565 123.755 73.760  1.00 39.68  ? 37  LEU G CD2   1 
ATOM   6706 N N     . MET D 2 38  ? 97.490  122.042 72.093  1.00 45.46  ? 38  MET G N     1 
ATOM   6707 C CA    . MET D 2 38  ? 96.181  121.627 72.583  1.00 45.46  ? 38  MET G CA    1 
ATOM   6708 C C     . MET D 2 38  ? 95.825  120.232 72.090  1.00 45.46  ? 38  MET G C     1 
ATOM   6709 O O     . MET D 2 38  ? 95.397  119.385 72.882  1.00 45.46  ? 38  MET G O     1 
ATOM   6710 C CB    . MET D 2 38  ? 95.119  122.639 72.145  1.00 45.46  ? 38  MET G CB    1 
ATOM   6711 C CG    . MET D 2 38  ? 93.712  122.350 72.652  1.00 45.46  ? 38  MET G CG    1 
ATOM   6712 S SD    . MET D 2 38  ? 92.823  121.127 71.667  1.00 45.46  ? 38  MET G SD    1 
ATOM   6713 C CE    . MET D 2 38  ? 92.479  122.068 70.182  1.00 45.46  ? 38  MET G CE    1 
ATOM   6714 N N     . ALA D 2 39  ? 96.009  119.970 70.795  1.00 44.00  ? 39  ALA G N     1 
ATOM   6715 C CA    . ALA D 2 39  ? 95.691  118.654 70.254  1.00 44.00  ? 39  ALA G CA    1 
ATOM   6716 C C     . ALA D 2 39  ? 96.567  117.577 70.879  1.00 44.00  ? 39  ALA G C     1 
ATOM   6717 O O     . ALA D 2 39  ? 96.076  116.499 71.236  1.00 44.00  ? 39  ALA G O     1 
ATOM   6718 C CB    . ALA D 2 39  ? 95.852  118.661 68.735  1.00 44.00  ? 39  ALA G CB    1 
ATOM   6719 N N     . TYR D 2 40  ? 97.867  117.849 71.023  1.00 37.93  ? 40  TYR G N     1 
ATOM   6720 C CA    . TYR D 2 40  ? 98.762  116.857 71.602  1.00 37.93  ? 40  TYR G CA    1 
ATOM   6721 C C     . TYR D 2 40  ? 98.409  116.532 73.045  1.00 37.93  ? 40  TYR G C     1 
ATOM   6722 O O     . TYR D 2 40  ? 98.427  115.355 73.421  1.00 37.93  ? 40  TYR G O     1 
ATOM   6723 C CB    . TYR D 2 40  ? 100.211 117.334 71.534  1.00 37.93  ? 40  TYR G CB    1 
ATOM   6724 C CG    . TYR D 2 40  ? 101.194 116.285 71.996  1.00 37.93  ? 40  TYR G CG    1 
ATOM   6725 C CD1   . TYR D 2 40  ? 101.733 115.368 71.103  1.00 37.93  ? 40  TYR G CD1   1 
ATOM   6726 C CD2   . TYR D 2 40  ? 101.578 116.206 73.326  1.00 37.93  ? 40  TYR G CD2   1 
ATOM   6727 C CE1   . TYR D 2 40  ? 102.628 114.404 71.523  1.00 37.93  ? 40  TYR G CE1   1 
ATOM   6728 C CE2   . TYR D 2 40  ? 102.469 115.247 73.754  1.00 37.93  ? 40  TYR G CE2   1 
ATOM   6729 C CZ    . TYR D 2 40  ? 102.995 114.349 72.850  1.00 37.93  ? 40  TYR G CZ    1 
ATOM   6730 O OH    . TYR D 2 40  ? 103.887 113.391 73.274  1.00 37.93  ? 40  TYR G OH    1 
ATOM   6731 N N     . CYS D 2 41  ? 98.088  117.536 73.859  1.00 37.57  ? 41  CYS G N     1 
ATOM   6732 C CA    . CYS D 2 41  ? 97.752  117.313 75.257  1.00 37.57  ? 41  CYS G CA    1 
ATOM   6733 C C     . CYS D 2 41  ? 96.323  116.825 75.445  1.00 37.57  ? 41  CYS G C     1 
ATOM   6734 O O     . CYS D 2 41  ? 95.979  116.370 76.540  1.00 37.57  ? 41  CYS G O     1 
ATOM   6735 C CB    . CYS D 2 41  ? 97.971  118.595 76.066  1.00 37.57  ? 41  CYS G CB    1 
ATOM   6736 S SG    . CYS D 2 41  ? 96.830  119.931 75.665  1.00 37.57  ? 41  CYS G SG    1 
ATOM   6737 N N     . GLU D 2 42  ? 95.485  116.913 74.413  1.00 41.96  ? 42  GLU G N     1 
ATOM   6738 C CA    . GLU D 2 42  ? 94.167  116.293 74.455  1.00 41.96  ? 42  GLU G CA    1 
ATOM   6739 C C     . GLU D 2 42  ? 94.215  114.824 74.057  1.00 41.96  ? 42  GLU G C     1 
ATOM   6740 O O     . GLU D 2 42  ? 93.492  114.003 74.630  1.00 41.96  ? 42  GLU G O     1 
ATOM   6741 C CB    . GLU D 2 42  ? 93.201  117.043 73.534  1.00 41.96  ? 42  GLU G CB    1 
ATOM   6742 C CG    . GLU D 2 42  ? 92.571  118.279 74.164  1.00 41.96  ? 42  GLU G CG    1 
ATOM   6743 C CD    . GLU D 2 42  ? 91.198  118.012 74.757  1.00 41.96  ? 42  GLU G CD    1 
ATOM   6744 O OE1   . GLU D 2 42  ? 90.600  116.959 74.450  1.00 41.96  ? 42  GLU G OE1   1 
ATOM   6745 O OE2   . GLU D 2 42  ? 90.713  118.861 75.534  1.00 41.96  ? 42  GLU G OE2   1 
ATOM   6746 N N     . ALA D 2 43  ? 95.058  114.478 73.081  1.00 41.40  ? 43  ALA G N     1 
ATOM   6747 C CA    . ALA D 2 43  ? 95.139  113.103 72.607  1.00 41.40  ? 43  ALA G CA    1 
ATOM   6748 C C     . ALA D 2 43  ? 95.869  112.180 73.575  1.00 41.40  ? 43  ALA G C     1 
ATOM   6749 O O     . ALA D 2 43  ? 95.724  110.957 73.469  1.00 41.40  ? 43  ALA G O     1 
ATOM   6750 C CB    . ALA D 2 43  ? 95.832  113.061 71.244  1.00 41.40  ? 43  ALA G CB    1 
ATOM   6751 N N     . HIS D 2 44  ? 96.641  112.730 74.511  1.00 38.58  ? 44  HIS G N     1 
ATOM   6752 C CA    . HIS D 2 44  ? 97.412  111.945 75.470  1.00 38.58  ? 44  HIS G CA    1 
ATOM   6753 C C     . HIS D 2 44  ? 96.890  112.132 76.892  1.00 38.58  ? 44  HIS G C     1 
ATOM   6754 O O     . HIS D 2 44  ? 97.619  111.945 77.866  1.00 38.58  ? 44  HIS G O     1 
ATOM   6755 C CB    . HIS D 2 44  ? 98.891  112.318 75.402  1.00 38.58  ? 44  HIS G CB    1 
ATOM   6756 C CG    . HIS D 2 44  ? 99.544  111.973 74.100  1.00 38.58  ? 44  HIS G CG    1 
ATOM   6757 N ND1   . HIS D 2 44  ? 99.474  112.792 72.994  1.00 38.58  ? 44  HIS G ND1   1 
ATOM   6758 C CD2   . HIS D 2 44  ? 100.286 110.903 73.730  1.00 38.58  ? 44  HIS G CD2   1 
ATOM   6759 C CE1   . HIS D 2 44  ? 100.141 112.239 71.997  1.00 38.58  ? 44  HIS G CE1   1 
ATOM   6760 N NE2   . HIS D 2 44  ? 100.643 111.092 72.417  1.00 38.58  ? 44  HIS G NE2   1 
ATOM   6761 N N     . ALA D 2 45  ? 95.613  112.486 77.027  1.00 34.57  ? 45  ALA G N     1 
ATOM   6762 C CA    . ALA D 2 45  ? 95.016  112.792 78.321  1.00 34.57  ? 45  ALA G CA    1 
ATOM   6763 C C     . ALA D 2 45  ? 94.446  111.565 79.014  1.00 34.57  ? 45  ALA G C     1 
ATOM   6764 O O     . ALA D 2 45  ? 94.611  111.408 80.227  1.00 34.57  ? 45  ALA G O     1 
ATOM   6765 C CB    . ALA D 2 45  ? 93.915  113.848 78.151  1.00 34.57  ? 45  ALA G CB    1 
ATOM   6766 N N     . LYS D 2 46  ? 93.774  110.682 78.272  1.00 34.59  ? 46  LYS G N     1 
ATOM   6767 C CA    . LYS D 2 46  ? 93.184  109.498 78.883  1.00 34.59  ? 46  LYS G CA    1 
ATOM   6768 C C     . LYS D 2 46  ? 94.239  108.587 79.500  1.00 34.59  ? 46  LYS G C     1 
ATOM   6769 O O     . LYS D 2 46  ? 93.915  107.799 80.395  1.00 34.59  ? 46  LYS G O     1 
ATOM   6770 C CB    . LYS D 2 46  ? 92.362  108.735 77.839  1.00 34.59  ? 46  LYS G CB    1 
ATOM   6771 C CG    . LYS D 2 46  ? 91.797  107.400 78.311  1.00 34.59  ? 46  LYS G CG    1 
ATOM   6772 C CD    . LYS D 2 46  ? 90.653  107.606 79.295  1.00 34.59  ? 46  LYS G CD    1 
ATOM   6773 C CE    . LYS D 2 46  ? 89.774  106.368 79.436  1.00 34.59  ? 46  LYS G CE    1 
ATOM   6774 N NZ    . LYS D 2 46  ? 89.382  105.766 78.131  1.00 34.59  ? 46  LYS G NZ    1 
ATOM   6775 N N     . GLU D 2 47  ? 95.490  108.681 79.050  1.00 33.85  ? 47  GLU G N     1 
ATOM   6776 C CA    . GLU D 2 47  ? 96.580  107.856 79.556  1.00 33.85  ? 47  GLU G CA    1 
ATOM   6777 C C     . GLU D 2 47  ? 97.578  108.670 80.374  1.00 33.85  ? 47  GLU G C     1 
ATOM   6778 O O     . GLU D 2 47  ? 98.778  108.388 80.358  1.00 33.85  ? 47  GLU G O     1 
ATOM   6779 C CB    . GLU D 2 47  ? 97.293  107.149 78.404  1.00 33.85  ? 47  GLU G CB    1 
ATOM   6780 C CG    . GLU D 2 47  ? 96.361  106.449 77.426  1.00 33.85  ? 47  GLU G CG    1 
ATOM   6781 C CD    . GLU D 2 47  ? 95.601  105.304 78.066  1.00 33.85  ? 47  GLU G CD    1 
ATOM   6782 O OE1   . GLU D 2 47  ? 96.240  104.292 78.423  1.00 33.85  ? 47  GLU G OE1   1 
ATOM   6783 O OE2   . GLU D 2 47  ? 94.367  105.415 78.215  1.00 33.85  ? 47  GLU G OE2   1 
ATOM   6784 N N     . ASP D 2 48  ? 97.095  109.682 81.096  1.00 25.54  ? 48  ASP G N     1 
ATOM   6785 C CA    . ASP D 2 48  ? 97.942  110.505 81.954  1.00 25.54  ? 48  ASP G CA    1 
ATOM   6786 C C     . ASP D 2 48  ? 97.552  110.267 83.408  1.00 25.54  ? 48  ASP G C     1 
ATOM   6787 O O     . ASP D 2 48  ? 96.577  110.861 83.893  1.00 25.54  ? 48  ASP G O     1 
ATOM   6788 C CB    . ASP D 2 48  ? 97.801  111.987 81.595  1.00 25.54  ? 48  ASP G CB    1 
ATOM   6789 C CG    . ASP D 2 48  ? 98.861  112.851 82.253  1.00 25.54  ? 48  ASP G CG    1 
ATOM   6790 O OD1   . ASP D 2 48  ? 98.982  112.807 83.495  1.00 25.54  ? 48  ASP G OD1   1 
ATOM   6791 O OD2   . ASP D 2 48  ? 99.573  113.578 81.530  1.00 25.54  ? 48  ASP G OD2   1 
ATOM   6792 N N     . PRO D 2 49  ? 98.270  109.414 84.144  1.00 21.20  ? 49  PRO G N     1 
ATOM   6793 C CA    . PRO D 2 49  ? 97.849  109.124 85.528  1.00 21.20  ? 49  PRO G CA    1 
ATOM   6794 C C     . PRO D 2 49  ? 97.774  110.356 86.415  1.00 21.20  ? 49  PRO G C     1 
ATOM   6795 O O     . PRO D 2 49  ? 96.777  110.543 87.125  1.00 21.20  ? 49  PRO G O     1 
ATOM   6796 C CB    . PRO D 2 49  ? 98.914  108.129 86.011  1.00 21.20  ? 49  PRO G CB    1 
ATOM   6797 C CG    . PRO D 2 49  ? 99.469  107.520 84.769  1.00 21.20  ? 49  PRO G CG    1 
ATOM   6798 C CD    . PRO D 2 49  ? 99.409  108.581 83.721  1.00 21.20  ? 49  PRO G CD    1 
ATOM   6799 N N     . LEU D 2 50  ? 98.800  111.209 86.394  1.00 15.78  ? 50  LEU G N     1 
ATOM   6800 C CA    . LEU D 2 50  ? 98.801  112.385 87.258  1.00 15.78  ? 50  LEU G CA    1 
ATOM   6801 C C     . LEU D 2 50  ? 97.625  113.309 86.978  1.00 15.78  ? 50  LEU G C     1 
ATOM   6802 O O     . LEU D 2 50  ? 97.220  114.065 87.867  1.00 15.78  ? 50  LEU G O     1 
ATOM   6803 C CB    . LEU D 2 50  ? 100.110 113.153 87.094  1.00 15.78  ? 50  LEU G CB    1 
ATOM   6804 C CG    . LEU D 2 50  ? 101.365 112.372 87.483  1.00 15.78  ? 50  LEU G CG    1 
ATOM   6805 C CD1   . LEU D 2 50  ? 102.593 112.988 86.839  1.00 15.78  ? 50  LEU G CD1   1 
ATOM   6806 C CD2   . LEU D 2 50  ? 101.512 112.310 88.994  1.00 15.78  ? 50  LEU G CD2   1 
ATOM   6807 N N     . LEU D 2 51  ? 97.070  113.266 85.769  1.00 24.17  ? 51  LEU G N     1 
ATOM   6808 C CA    . LEU D 2 51  ? 95.913  114.072 85.408  1.00 24.17  ? 51  LEU G CA    1 
ATOM   6809 C C     . LEU D 2 51  ? 94.601  113.328 85.613  1.00 24.17  ? 51  LEU G C     1 
ATOM   6810 O O     . LEU D 2 51  ? 93.600  113.939 86.002  1.00 24.17  ? 51  LEU G O     1 
ATOM   6811 C CB    . LEU D 2 51  ? 96.029  114.519 83.947  1.00 24.17  ? 51  LEU G CB    1 
ATOM   6812 C CG    . LEU D 2 51  ? 94.958  115.475 83.423  1.00 24.17  ? 51  LEU G CG    1 
ATOM   6813 C CD1   . LEU D 2 51  ? 95.218  116.884 83.927  1.00 24.17  ? 51  LEU G CD1   1 
ATOM   6814 C CD2   . LEU D 2 51  ? 94.922  115.444 81.904  1.00 24.17  ? 51  LEU G CD2   1 
ATOM   6815 N N     . THR D 2 52  ? 94.587  112.022 85.358  1.00 26.51  ? 52  THR G N     1 
ATOM   6816 C CA    . THR D 2 52  ? 93.431  111.161 85.610  1.00 26.51  ? 52  THR G CA    1 
ATOM   6817 C C     . THR D 2 52  ? 93.918  109.916 86.342  1.00 26.51  ? 52  THR G C     1 
ATOM   6818 O O     . THR D 2 52  ? 94.143  108.866 85.727  1.00 26.51  ? 52  THR G O     1 
ATOM   6819 C CB    . THR D 2 52  ? 92.720  110.791 84.308  1.00 26.51  ? 52  THR G CB    1 
ATOM   6820 O OG1   . THR D 2 52  ? 93.560  109.932 83.526  1.00 26.51  ? 52  THR G OG1   1 
ATOM   6821 C CG2   . THR D 2 52  ? 92.390  112.040 83.505  1.00 26.51  ? 52  THR G CG2   1 
ATOM   6822 N N     . PRO D 2 53  ? 94.095  109.997 87.665  1.00 25.36  ? 53  PRO G N     1 
ATOM   6823 C CA    . PRO D 2 53  ? 94.716  108.874 88.388  1.00 25.36  ? 53  PRO G CA    1 
ATOM   6824 C C     . PRO D 2 53  ? 94.150  107.462 88.299  1.00 25.36  ? 53  PRO G C     1 
ATOM   6825 O O     . PRO D 2 53  ? 92.932  107.257 88.313  1.00 25.36  ? 53  PRO G O     1 
ATOM   6826 C CB    . PRO D 2 53  ? 94.838  109.391 89.832  1.00 25.36  ? 53  PRO G CB    1 
ATOM   6827 C CG    . PRO D 2 53  ? 93.878  110.527 89.932  1.00 25.36  ? 53  PRO G CG    1 
ATOM   6828 C CD    . PRO D 2 53  ? 93.751  111.117 88.560  1.00 25.36  ? 53  PRO G CD    1 
ATOM   6829 N N     . VAL D 2 54  ? 95.047  106.485 88.207  1.00 23.77  ? 54  VAL G N     1 
ATOM   6830 C CA    . VAL D 2 54  ? 94.688  105.080 88.033  1.00 23.77  ? 54  VAL G CA    1 
ATOM   6831 C C     . VAL D 2 54  ? 94.028  104.572 89.310  1.00 23.77  ? 54  VAL G C     1 
ATOM   6832 O O     . VAL D 2 54  ? 94.340  105.069 90.402  1.00 23.77  ? 54  VAL G O     1 
ATOM   6833 C CB    . VAL D 2 54  ? 95.929  104.244 87.676  1.00 23.77  ? 54  VAL G CB    1 
ATOM   6834 C CG1   . VAL D 2 54  ? 96.873  104.155 88.869  1.00 23.77  ? 54  VAL G CG1   1 
ATOM   6835 C CG2   . VAL D 2 54  ? 95.536  102.856 87.194  1.00 23.77  ? 54  VAL G CG2   1 
ATOM   6836 N N     . PRO D 2 55  ? 93.118  103.599 89.234  1.00 26.94  ? 55  PRO G N     1 
ATOM   6837 C CA    . PRO D 2 55  ? 92.587  103.001 90.465  1.00 26.94  ? 55  PRO G CA    1 
ATOM   6838 C C     . PRO D 2 55  ? 93.695  102.388 91.308  1.00 26.94  ? 55  PRO G C     1 
ATOM   6839 O O     . PRO D 2 55  ? 94.729  101.951 90.797  1.00 26.94  ? 55  PRO G O     1 
ATOM   6840 C CB    . PRO D 2 55  ? 91.607  101.934 89.956  1.00 26.94  ? 55  PRO G CB    1 
ATOM   6841 C CG    . PRO D 2 55  ? 91.877  101.803 88.483  1.00 26.94  ? 55  PRO G CG    1 
ATOM   6842 C CD    . PRO D 2 55  ? 92.369  103.140 88.054  1.00 26.94  ? 55  PRO G CD    1 
ATOM   6843 N N     . ALA D 2 56  ? 93.463  102.365 92.623  1.00 27.05  ? 56  ALA G N     1 
ATOM   6844 C CA    . ALA D 2 56  ? 94.505  101.962 93.562  1.00 27.05  ? 56  ALA G CA    1 
ATOM   6845 C C     . ALA D 2 56  ? 95.064  100.581 93.251  1.00 27.05  ? 56  ALA G C     1 
ATOM   6846 O O     . ALA D 2 56  ? 96.231  100.303 93.552  1.00 27.05  ? 56  ALA G O     1 
ATOM   6847 C CB    . ALA D 2 56  ? 93.957  101.991 94.990  1.00 27.05  ? 56  ALA G CB    1 
ATOM   6848 N N     . SER D 2 57  ? 94.256  99.700  92.659  1.00 28.26  ? 57  SER G N     1 
ATOM   6849 C CA    . SER D 2 57  ? 94.719  98.342  92.390  1.00 28.26  ? 57  SER G CA    1 
ATOM   6850 C C     . SER D 2 57  ? 95.953  98.349  91.496  1.00 28.26  ? 57  SER G C     1 
ATOM   6851 O O     . SER D 2 57  ? 96.978  97.741  91.825  1.00 28.26  ? 57  SER G O     1 
ATOM   6852 C CB    . SER D 2 57  ? 93.596  97.527  91.749  1.00 28.26  ? 57  SER G CB    1 
ATOM   6853 O OG    . SER D 2 57  ? 92.426  97.554  92.548  1.00 28.26  ? 57  SER G OG    1 
ATOM   6854 N N     . GLU D 2 58  ? 95.874  99.039  90.356  1.00 24.97  ? 58  GLU G N     1 
ATOM   6855 C CA    . GLU D 2 58  ? 96.996  99.061  89.424  1.00 24.97  ? 58  GLU G CA    1 
ATOM   6856 C C     . GLU D 2 58  ? 98.097  100.011 89.879  1.00 24.97  ? 58  GLU G C     1 
ATOM   6857 O O     . GLU D 2 58  ? 99.263  99.823  89.513  1.00 24.97  ? 58  GLU G O     1 
ATOM   6858 C CB    . GLU D 2 58  ? 96.508  99.451  88.029  1.00 24.97  ? 58  GLU G CB    1 
ATOM   6859 C CG    . GLU D 2 58  ? 95.663  98.385  87.349  1.00 24.97  ? 58  GLU G CG    1 
ATOM   6860 C CD    . GLU D 2 58  ? 96.456  97.135  87.016  1.00 24.97  ? 58  GLU G CD    1 
ATOM   6861 O OE1   . GLU D 2 58  ? 97.640  97.263  86.640  1.00 24.97  ? 58  GLU G OE1   1 
ATOM   6862 O OE2   . GLU D 2 58  ? 95.895  96.025  87.130  1.00 24.97  ? 58  GLU G OE2   1 
ATOM   6863 N N     . ASN D 2 59  ? 97.752  101.032 90.664  1.00 18.97  ? 59  ASN G N     1 
ATOM   6864 C CA    . ASN D 2 59  ? 98.700  102.062 91.070  1.00 18.97  ? 59  ASN G CA    1 
ATOM   6865 C C     . ASN D 2 59  ? 99.920  101.409 91.714  1.00 18.97  ? 59  ASN G C     1 
ATOM   6866 O O     . ASN D 2 59  ? 99.802  100.821 92.796  1.00 18.97  ? 59  ASN G O     1 
ATOM   6867 C CB    . ASN D 2 59  ? 98.031  103.043 92.040  1.00 18.97  ? 59  ASN G CB    1 
ATOM   6868 C CG    . ASN D 2 59  ? 98.996  104.080 92.602  1.00 18.97  ? 59  ASN G CG    1 
ATOM   6869 O OD1   . ASN D 2 59  ? 100.208 103.874 92.650  1.00 18.97  ? 59  ASN G OD1   1 
ATOM   6870 N ND2   . ASN D 2 59  ? 98.448  105.211 93.032  1.00 18.97  ? 59  ASN G ND2   1 
ATOM   6871 N N     . PRO D 2 60  ? 101.103 101.482 91.093  1.00 13.86  ? 60  PRO G N     1 
ATOM   6872 C CA    . PRO D 2 60  ? 102.299 100.902 91.723  1.00 13.86  ? 60  PRO G CA    1 
ATOM   6873 C C     . PRO D 2 60  ? 102.703 101.577 93.023  1.00 13.86  ? 60  PRO G C     1 
ATOM   6874 O O     . PRO D 2 60  ? 103.441 100.971 93.807  1.00 13.86  ? 60  PRO G O     1 
ATOM   6875 C CB    . PRO D 2 60  ? 103.385 101.085 90.654  1.00 13.86  ? 60  PRO G CB    1 
ATOM   6876 C CG    . PRO D 2 60  ? 102.907 102.184 89.795  1.00 13.86  ? 60  PRO G CG    1 
ATOM   6877 C CD    . PRO D 2 60  ? 101.414 102.109 89.797  1.00 13.86  ? 60  PRO G CD    1 
ATOM   6878 N N     . PHE D 2 61  ? 102.257 102.804 93.269  1.00 11.13  ? 61  PHE G N     1 
ATOM   6879 C CA    . PHE D 2 61  ? 102.563 103.502 94.511  1.00 11.13  ? 61  PHE G CA    1 
ATOM   6880 C C     . PHE D 2 61  ? 101.344 103.526 95.426  1.00 11.13  ? 61  PHE G C     1 
ATOM   6881 O O     . PHE D 2 61  ? 100.423 104.318 95.227  1.00 11.13  ? 61  PHE G O     1 
ATOM   6882 C CB    . PHE D 2 61  ? 103.036 104.928 94.226  1.00 11.13  ? 61  PHE G CB    1 
ATOM   6883 C CG    . PHE D 2 61  ? 104.241 105.001 93.333  1.00 11.13  ? 61  PHE G CG    1 
ATOM   6884 C CD1   . PHE D 2 61  ? 105.516 104.882 93.859  1.00 11.13  ? 61  PHE G CD1   1 
ATOM   6885 C CD2   . PHE D 2 61  ? 104.099 105.192 91.969  1.00 11.13  ? 61  PHE G CD2   1 
ATOM   6886 C CE1   . PHE D 2 61  ? 106.625 104.950 93.042  1.00 11.13  ? 61  PHE G CE1   1 
ATOM   6887 C CE2   . PHE D 2 61  ? 105.204 105.261 91.148  1.00 11.13  ? 61  PHE G CE2   1 
ATOM   6888 C CZ    . PHE D 2 61  ? 106.469 105.140 91.685  1.00 11.13  ? 61  PHE G CZ    1 
ATOM   6889 N N     . VAL E 4 2   ? 135.991 87.642  87.314  1.00 12.83  ? 2   VAL S N     1 
ATOM   6890 C CA    . VAL E 4 2   ? 135.236 86.856  88.329  1.00 12.83  ? 2   VAL S CA    1 
ATOM   6891 C C     . VAL E 4 2   ? 135.848 85.468  88.453  1.00 12.83  ? 2   VAL S C     1 
ATOM   6892 O O     . VAL E 4 2   ? 136.120 84.808  87.452  1.00 12.83  ? 2   VAL S O     1 
ATOM   6893 C CB    . VAL E 4 2   ? 133.741 86.767  87.968  1.00 12.83  ? 2   VAL S CB    1 
ATOM   6894 C CG1   . VAL E 4 2   ? 133.054 88.090  88.243  1.00 12.83  ? 2   VAL S CG1   1 
ATOM   6895 C CG2   . VAL E 4 2   ? 133.562 86.364  86.510  1.00 12.83  ? 2   VAL S CG2   1 
ATOM   6896 N N     . GLN E 4 3   ? 136.071 85.028  89.689  1.00 15.45  ? 3   GLN S N     1 
ATOM   6897 C CA    . GLN E 4 3   ? 136.689 83.727  89.930  1.00 15.45  ? 3   GLN S CA    1 
ATOM   6898 C C     . GLN E 4 3   ? 136.310 83.254  91.323  1.00 15.45  ? 3   GLN S C     1 
ATOM   6899 O O     . GLN E 4 3   ? 136.551 83.964  92.305  1.00 15.45  ? 3   GLN S O     1 
ATOM   6900 C CB    . GLN E 4 3   ? 138.208 83.811  89.781  1.00 15.45  ? 3   GLN S CB    1 
ATOM   6901 C CG    . GLN E 4 3   ? 138.877 82.478  89.502  1.00 15.45  ? 3   GLN S CG    1 
ATOM   6902 C CD    . GLN E 4 3   ? 140.384 82.596  89.396  1.00 15.45  ? 3   GLN S CD    1 
ATOM   6903 O OE1   . GLN E 4 3   ? 140.937 83.694  89.439  1.00 15.45  ? 3   GLN S OE1   1 
ATOM   6904 N NE2   . GLN E 4 3   ? 141.059 81.460  89.260  1.00 15.45  ? 3   GLN S NE2   1 
ATOM   6905 N N     . LEU E 4 4   ? 135.713 82.066  91.404  1.00 14.00  ? 4   LEU S N     1 
ATOM   6906 C CA    . LEU E 4 4   ? 135.377 81.414  92.666  1.00 14.00  ? 4   LEU S CA    1 
ATOM   6907 C C     . LEU E 4 4   ? 136.006 80.027  92.648  1.00 14.00  ? 4   LEU S C     1 
ATOM   6908 O O     . LEU E 4 4   ? 135.582 79.161  91.876  1.00 14.00  ? 4   LEU S O     1 
ATOM   6909 C CB    . LEU E 4 4   ? 133.864 81.326  92.854  1.00 14.00  ? 4   LEU S CB    1 
ATOM   6910 C CG    . LEU E 4 4   ? 133.137 82.637  93.155  1.00 14.00  ? 4   LEU S CG    1 
ATOM   6911 C CD1   . LEU E 4 4   ? 131.646 82.482  92.929  1.00 14.00  ? 4   LEU S CD1   1 
ATOM   6912 C CD2   . LEU E 4 4   ? 133.415 83.092  94.574  1.00 14.00  ? 4   LEU S CD2   1 
ATOM   6913 N N     . VAL E 4 5   ? 137.011 79.815  93.494  1.00 17.50  ? 5   VAL S N     1 
ATOM   6914 C CA    . VAL E 4 5   ? 137.757 78.560  93.530  1.00 17.50  ? 5   VAL S CA    1 
ATOM   6915 C C     . VAL E 4 5   ? 137.504 77.890  94.872  1.00 17.50  ? 5   VAL S C     1 
ATOM   6916 O O     . VAL E 4 5   ? 137.765 78.477  95.929  1.00 17.50  ? 5   VAL S O     1 
ATOM   6917 C CB    . VAL E 4 5   ? 139.258 78.788  93.301  1.00 17.50  ? 5   VAL S CB    1 
ATOM   6918 C CG1   . VAL E 4 5   ? 140.021 77.478  93.444  1.00 17.50  ? 5   VAL S CG1   1 
ATOM   6919 C CG2   . VAL E 4 5   ? 139.495 79.403  91.933  1.00 17.50  ? 5   VAL S CG2   1 
ATOM   6920 N N     . GLU E 4 6   ? 137.004 76.661  94.830  1.00 22.32  ? 6   GLU S N     1 
ATOM   6921 C CA    . GLU E 4 6   ? 136.712 75.888  96.026  1.00 22.32  ? 6   GLU S CA    1 
ATOM   6922 C C     . GLU E 4 6   ? 137.869 74.955  96.361  1.00 22.32  ? 6   GLU S C     1 
ATOM   6923 O O     . GLU E 4 6   ? 138.702 74.621  95.515  1.00 22.32  ? 6   GLU S O     1 
ATOM   6924 C CB    . GLU E 4 6   ? 135.427 75.078  95.847  1.00 22.32  ? 6   GLU S CB    1 
ATOM   6925 C CG    . GLU E 4 6   ? 134.182 75.928  95.648  1.00 22.32  ? 6   GLU S CG    1 
ATOM   6926 C CD    . GLU E 4 6   ? 133.801 76.083  94.192  1.00 22.32  ? 6   GLU S CD    1 
ATOM   6927 O OE1   . GLU E 4 6   ? 134.646 75.798  93.319  1.00 22.32  ? 6   GLU S OE1   1 
ATOM   6928 O OE2   . GLU E 4 6   ? 132.650 76.476  93.918  1.00 22.32  ? 6   GLU S OE2   1 
ATOM   6929 N N     . SER E 4 7   ? 137.905 74.536  97.622  1.00 27.38  ? 7   SER S N     1 
ATOM   6930 C CA    . SER E 4 7   ? 138.948 73.643  98.107  1.00 27.38  ? 7   SER S CA    1 
ATOM   6931 C C     . SER E 4 7   ? 138.458 72.981  99.387  1.00 27.38  ? 7   SER S C     1 
ATOM   6932 O O     . SER E 4 7   ? 137.432 73.361  99.954  1.00 27.38  ? 7   SER S O     1 
ATOM   6933 C CB    . SER E 4 7   ? 140.261 74.394  98.346  1.00 27.38  ? 7   SER S CB    1 
ATOM   6934 O OG    . SER E 4 7   ? 140.134 75.317  99.414  1.00 27.38  ? 7   SER S OG    1 
ATOM   6935 N N     . GLY E 4 8   ? 139.218 71.987  99.841  1.00 29.65  ? 8   GLY S N     1 
ATOM   6936 C CA    . GLY E 4 8   ? 138.898 71.255  101.051 1.00 29.65  ? 8   GLY S CA    1 
ATOM   6937 C C     . GLY E 4 8   ? 138.243 69.912  100.821 1.00 29.65  ? 8   GLY S C     1 
ATOM   6938 O O     . GLY E 4 8   ? 137.897 69.239  101.799 1.00 29.65  ? 8   GLY S O     1 
ATOM   6939 N N     . GLY E 4 9   ? 138.059 69.498  99.569  1.00 32.12  ? 9   GLY S N     1 
ATOM   6940 C CA    . GLY E 4 9   ? 137.448 68.219  99.288  1.00 32.12  ? 9   GLY S CA    1 
ATOM   6941 C C     . GLY E 4 9   ? 138.409 67.060  99.469  1.00 32.12  ? 9   GLY S C     1 
ATOM   6942 O O     . GLY E 4 9   ? 139.622 67.226  99.590  1.00 32.12  ? 9   GLY S O     1 
ATOM   6943 N N     . GLY E 4 10  ? 137.843 65.864  99.488  1.00 36.89  ? 10  GLY S N     1 
ATOM   6944 C CA    . GLY E 4 10  ? 138.617 64.652  99.658  1.00 36.89  ? 10  GLY S CA    1 
ATOM   6945 C C     . GLY E 4 10  ? 137.723 63.520  100.122 1.00 36.89  ? 10  GLY S C     1 
ATOM   6946 O O     . GLY E 4 10  ? 136.503 63.614  100.054 1.00 36.89  ? 10  GLY S O     1 
ATOM   6947 N N     . LEU E 4 11  ? 138.356 62.451  100.594 1.00 39.97  ? 11  LEU S N     1 
ATOM   6948 C CA    . LEU E 4 11  ? 137.647 61.293  101.122 1.00 39.97  ? 11  LEU S CA    1 
ATOM   6949 C C     . LEU E 4 11  ? 137.625 61.374  102.643 1.00 39.97  ? 11  LEU S C     1 
ATOM   6950 O O     . LEU E 4 11  ? 138.652 61.657  103.269 1.00 39.97  ? 11  LEU S O     1 
ATOM   6951 C CB    . LEU E 4 11  ? 138.298 59.989  100.652 1.00 39.97  ? 11  LEU S CB    1 
ATOM   6952 C CG    . LEU E 4 11  ? 139.750 59.696  101.048 1.00 39.97  ? 11  LEU S CG    1 
ATOM   6953 C CD1   . LEU E 4 11  ? 139.849 59.047  102.426 1.00 39.97  ? 11  LEU S CD1   1 
ATOM   6954 C CD2   . LEU E 4 11  ? 140.416 58.824  99.995  1.00 39.97  ? 11  LEU S CD2   1 
ATOM   6955 N N     . VAL E 4 12  ? 136.450 61.158  103.228 1.00 40.17  ? 12  VAL S N     1 
ATOM   6956 C CA    . VAL E 4 12  ? 136.252 61.290  104.667 1.00 40.17  ? 12  VAL S CA    1 
ATOM   6957 C C     . VAL E 4 12  ? 135.384 60.138  105.149 1.00 40.17  ? 12  VAL S C     1 
ATOM   6958 O O     . VAL E 4 12  ? 134.357 59.828  104.537 1.00 40.17  ? 12  VAL S O     1 
ATOM   6959 C CB    . VAL E 4 12  ? 135.607 62.642  105.028 1.00 40.17  ? 12  VAL S CB    1 
ATOM   6960 C CG1   . VAL E 4 12  ? 134.187 62.714  104.492 1.00 40.17  ? 12  VAL S CG1   1 
ATOM   6961 C CG2   . VAL E 4 12  ? 135.627 62.856  106.534 1.00 40.17  ? 12  VAL S CG2   1 
ATOM   6962 N N     . GLN E 4 13  ? 135.794 59.505  106.245 1.00 44.54  ? 13  GLN S N     1 
ATOM   6963 C CA    . GLN E 4 13  ? 135.004 58.435  106.827 1.00 44.54  ? 13  GLN S CA    1 
ATOM   6964 C C     . GLN E 4 13  ? 133.776 59.006  107.536 1.00 44.54  ? 13  GLN S C     1 
ATOM   6965 O O     . GLN E 4 13  ? 133.773 60.169  107.946 1.00 44.54  ? 13  GLN S O     1 
ATOM   6966 C CB    . GLN E 4 13  ? 135.842 57.634  107.816 1.00 44.54  ? 13  GLN S CB    1 
ATOM   6967 C CG    . GLN E 4 13  ? 136.892 56.756  107.160 1.00 44.54  ? 13  GLN S CG    1 
ATOM   6968 C CD    . GLN E 4 13  ? 136.285 55.636  106.340 1.00 44.54  ? 13  GLN S CD    1 
ATOM   6969 O OE1   . GLN E 4 13  ? 135.368 54.948  106.790 1.00 44.54  ? 13  GLN S OE1   1 
ATOM   6970 N NE2   . GLN E 4 13  ? 136.791 55.448  105.127 1.00 44.54  ? 13  GLN S NE2   1 
ATOM   6971 N N     . PRO E 4 14  ? 132.717 58.210  107.691 1.00 44.86  ? 14  PRO S N     1 
ATOM   6972 C CA    . PRO E 4 14  ? 131.538 58.702  108.412 1.00 44.86  ? 14  PRO S CA    1 
ATOM   6973 C C     . PRO E 4 14  ? 131.882 59.070  109.847 1.00 44.86  ? 14  PRO S C     1 
ATOM   6974 O O     . PRO E 4 14  ? 132.742 58.457  110.483 1.00 44.86  ? 14  PRO S O     1 
ATOM   6975 C CB    . PRO E 4 14  ? 130.562 57.521  108.353 1.00 44.86  ? 14  PRO S CB    1 
ATOM   6976 C CG    . PRO E 4 14  ? 131.029 56.684  107.214 1.00 44.86  ? 14  PRO S CG    1 
ATOM   6977 C CD    . PRO E 4 14  ? 132.513 56.851  107.163 1.00 44.86  ? 14  PRO S CD    1 
ATOM   6978 N N     . GLY E 4 15  ? 131.194 60.091  110.355 1.00 42.32  ? 15  GLY S N     1 
ATOM   6979 C CA    . GLY E 4 15  ? 131.427 60.580  111.696 1.00 42.32  ? 15  GLY S CA    1 
ATOM   6980 C C     . GLY E 4 15  ? 132.503 61.637  111.813 1.00 42.32  ? 15  GLY S C     1 
ATOM   6981 O O     . GLY E 4 15  ? 132.749 62.125  112.924 1.00 42.32  ? 15  GLY S O     1 
ATOM   6982 N N     . GLY E 4 16  ? 133.156 62.004  110.710 1.00 41.81  ? 16  GLY S N     1 
ATOM   6983 C CA    . GLY E 4 16  ? 134.157 63.045  110.715 1.00 41.81  ? 16  GLY S CA    1 
ATOM   6984 C C     . GLY E 4 16  ? 133.578 64.401  110.335 1.00 41.81  ? 16  GLY S C     1 
ATOM   6985 O O     . GLY E 4 16  ? 132.408 64.546  109.989 1.00 41.81  ? 16  GLY S O     1 
ATOM   6986 N N     . SER E 4 17  ? 134.442 65.411  110.404 1.00 37.10  ? 17  SER S N     1 
ATOM   6987 C CA    . SER E 4 17  ? 134.067 66.781  110.091 1.00 37.10  ? 17  SER S CA    1 
ATOM   6988 C C     . SER E 4 17  ? 135.153 67.414  109.236 1.00 37.10  ? 17  SER S C     1 
ATOM   6989 O O     . SER E 4 17  ? 136.335 67.084  109.363 1.00 37.10  ? 17  SER S O     1 
ATOM   6990 C CB    . SER E 4 17  ? 133.851 67.608  111.365 1.00 37.10  ? 17  SER S CB    1 
ATOM   6991 O OG    . SER E 4 17  ? 135.079 67.850  112.030 1.00 37.10  ? 17  SER S OG    1 
ATOM   6992 N N     . ARG E 4 18  ? 134.742 68.331  108.362 1.00 34.35  ? 18  ARG S N     1 
ATOM   6993 C CA    . ARG E 4 18  ? 135.666 69.021  107.473 1.00 34.35  ? 18  ARG S CA    1 
ATOM   6994 C C     . ARG E 4 18  ? 135.163 70.438  107.246 1.00 34.35  ? 18  ARG S C     1 
ATOM   6995 O O     . ARG E 4 18  ? 134.121 70.838  107.766 1.00 34.35  ? 18  ARG S O     1 
ATOM   6996 C CB    . ARG E 4 18  ? 135.824 68.277  106.140 1.00 34.35  ? 18  ARG S CB    1 
ATOM   6997 C CG    . ARG E 4 18  ? 136.583 66.968  106.262 1.00 34.35  ? 18  ARG S CG    1 
ATOM   6998 C CD    . ARG E 4 18  ? 136.562 66.181  104.967 1.00 34.35  ? 18  ARG S CD    1 
ATOM   6999 N NE    . ARG E 4 18  ? 137.305 66.843  103.901 1.00 34.35  ? 18  ARG S NE    1 
ATOM   7000 C CZ    . ARG E 4 18  ? 138.616 66.743  103.727 1.00 34.35  ? 18  ARG S CZ    1 
ATOM   7001 N NH1   . ARG E 4 18  ? 139.372 66.037  104.551 1.00 34.35  ? 18  ARG S NH1   1 
ATOM   7002 N NH2   . ARG E 4 18  ? 139.183 67.368  102.700 1.00 34.35  ? 18  ARG S NH2   1 
ATOM   7003 N N     . LYS E 4 19  ? 135.922 71.211  106.472 1.00 26.10  ? 19  LYS S N     1 
ATOM   7004 C CA    . LYS E 4 19  ? 135.566 72.593  106.165 1.00 26.10  ? 19  LYS S CA    1 
ATOM   7005 C C     . LYS E 4 19  ? 135.891 72.878  104.706 1.00 26.10  ? 19  LYS S C     1 
ATOM   7006 O O     . LYS E 4 19  ? 137.064 73.015  104.342 1.00 26.10  ? 19  LYS S O     1 
ATOM   7007 C CB    . LYS E 4 19  ? 136.302 73.568  107.084 1.00 26.10  ? 19  LYS S CB    1 
ATOM   7008 C CG    . LYS E 4 19  ? 135.864 75.015  106.920 1.00 26.10  ? 19  LYS S CG    1 
ATOM   7009 C CD    . LYS E 4 19  ? 136.225 75.850  108.138 1.00 26.10  ? 19  LYS S CD    1 
ATOM   7010 C CE    . LYS E 4 19  ? 137.729 76.028  108.269 1.00 26.10  ? 19  LYS S CE    1 
ATOM   7011 N NZ    . LYS E 4 19  ? 138.103 77.442  108.543 1.00 26.10  ? 19  LYS S NZ    1 
ATOM   7012 N N     . LEU E 4 20  ? 134.857 72.965  103.876 1.00 23.96  ? 20  LEU S N     1 
ATOM   7013 C CA    . LEU E 4 20  ? 135.023 73.416  102.504 1.00 23.96  ? 20  LEU S CA    1 
ATOM   7014 C C     . LEU E 4 20  ? 135.266 74.919  102.490 1.00 23.96  ? 20  LEU S C     1 
ATOM   7015 O O     . LEU E 4 20  ? 134.602 75.675  103.205 1.00 23.96  ? 20  LEU S O     1 
ATOM   7016 C CB    . LEU E 4 20  ? 133.783 73.081  101.675 1.00 23.96  ? 20  LEU S CB    1 
ATOM   7017 C CG    . LEU E 4 20  ? 133.424 71.603  101.517 1.00 23.96  ? 20  LEU S CG    1 
ATOM   7018 C CD1   . LEU E 4 20  ? 132.297 71.445  100.509 1.00 23.96  ? 20  LEU S CD1   1 
ATOM   7019 C CD2   . LEU E 4 20  ? 134.632 70.781  101.099 1.00 23.96  ? 20  LEU S CD2   1 
ATOM   7020 N N     . SER E 4 21  ? 136.221 75.349  101.673 1.00 24.38  ? 21  SER S N     1 
ATOM   7021 C CA    . SER E 4 21  ? 136.584 76.752  101.558 1.00 24.38  ? 21  SER S CA    1 
ATOM   7022 C C     . SER E 4 21  ? 136.339 77.236  100.135 1.00 24.38  ? 21  SER S C     1 
ATOM   7023 O O     . SER E 4 21  ? 136.404 76.460  99.178  1.00 24.38  ? 21  SER S O     1 
ATOM   7024 C CB    . SER E 4 21  ? 138.052 76.971  101.937 1.00 24.38  ? 21  SER S CB    1 
ATOM   7025 O OG    . SER E 4 21  ? 138.297 76.574  103.275 1.00 24.38  ? 21  SER S OG    1 
ATOM   7026 N N     . CYS E 4 22  ? 136.061 78.531  100.010 1.00 19.22  ? 22  CYS S N     1 
ATOM   7027 C CA    . CYS E 4 22  ? 135.788 79.175  98.729  1.00 19.22  ? 22  CYS S CA    1 
ATOM   7028 C C     . CYS E 4 22  ? 136.502 80.517  98.704  1.00 19.22  ? 22  CYS S C     1 
ATOM   7029 O O     . CYS E 4 22  ? 136.161 81.418  99.478  1.00 19.22  ? 22  CYS S O     1 
ATOM   7030 C CB    . CYS E 4 22  ? 134.286 79.357  98.520  1.00 19.22  ? 22  CYS S CB    1 
ATOM   7031 S SG    . CYS E 4 22  ? 133.812 80.132  96.962  1.00 19.22  ? 22  CYS S SG    1 
ATOM   7032 N N     . SER E 4 23  ? 137.491 80.643  97.821  1.00 17.06  ? 23  SER S N     1 
ATOM   7033 C CA    . SER E 4 23  ? 138.218 81.889  97.632  1.00 17.06  ? 23  SER S CA    1 
ATOM   7034 C C     . SER E 4 23  ? 137.655 82.626  96.424  1.00 17.06  ? 23  SER S C     1 
ATOM   7035 O O     . SER E 4 23  ? 137.452 82.030  95.360  1.00 17.06  ? 23  SER S O     1 
ATOM   7036 C CB    . SER E 4 23  ? 139.710 81.619  97.441  1.00 17.06  ? 23  SER S CB    1 
ATOM   7037 O OG    . SER E 4 23  ? 139.946 80.916  96.234  1.00 17.06  ? 23  SER S OG    1 
ATOM   7038 N N     . ALA E 4 24  ? 137.409 83.921  96.594  1.00 14.98  ? 24  ALA S N     1 
ATOM   7039 C CA    . ALA E 4 24  ? 136.809 84.761  95.571  1.00 14.98  ? 24  ALA S CA    1 
ATOM   7040 C C     . ALA E 4 24  ? 137.804 85.816  95.109  1.00 14.98  ? 24  ALA S C     1 
ATOM   7041 O O     . ALA E 4 24  ? 138.626 86.304  95.889  1.00 14.98  ? 24  ALA S O     1 
ATOM   7042 C CB    . ALA E 4 24  ? 135.544 85.439  96.099  1.00 14.98  ? 24  ALA S CB    1 
ATOM   7043 N N     . SER E 4 25  ? 137.728 86.161  93.826  1.00 13.64  ? 25  SER S N     1 
ATOM   7044 C CA    . SER E 4 25  ? 138.616 87.180  93.271  1.00 13.64  ? 25  SER S CA    1 
ATOM   7045 C C     . SER E 4 25  ? 138.015 87.715  91.984  1.00 13.64  ? 25  SER S C     1 
ATOM   7046 O O     . SER E 4 25  ? 137.775 86.945  91.049  1.00 13.64  ? 25  SER S O     1 
ATOM   7047 C CB    . SER E 4 25  ? 140.008 86.603  93.014  1.00 13.64  ? 25  SER S CB    1 
ATOM   7048 O OG    . SER E 4 25  ? 139.971 85.617  91.997  1.00 13.64  ? 25  SER S OG    1 
ATOM   7049 N N     . GLY E 4 26  ? 137.772 89.024  91.934  1.00 12.14  ? 26  GLY S N     1 
ATOM   7050 C CA    . GLY E 4 26  ? 137.366 89.668  90.700  1.00 12.14  ? 26  GLY S CA    1 
ATOM   7051 C C     . GLY E 4 26  ? 136.026 90.372  90.753  1.00 12.14  ? 26  GLY S C     1 
ATOM   7052 O O     . GLY E 4 26  ? 135.474 90.722  89.707  1.00 12.14  ? 26  GLY S O     1 
ATOM   7053 N N     . PHE E 4 27  ? 135.486 90.589  91.949  1.00 11.17  ? 27  PHE S N     1 
ATOM   7054 C CA    . PHE E 4 27  ? 134.197 91.255  92.078  1.00 11.17  ? 27  PHE S CA    1 
ATOM   7055 C C     . PHE E 4 27  ? 134.059 91.803  93.490  1.00 11.17  ? 27  PHE S C     1 
ATOM   7056 O O     . PHE E 4 27  ? 134.883 91.536  94.368  1.00 11.17  ? 27  PHE S O     1 
ATOM   7057 C CB    . PHE E 4 27  ? 133.041 90.307  91.736  1.00 11.17  ? 27  PHE S CB    1 
ATOM   7058 C CG    . PHE E 4 27  ? 132.967 89.092  92.616  1.00 11.17  ? 27  PHE S CG    1 
ATOM   7059 C CD1   . PHE E 4 27  ? 133.901 88.077  92.501  1.00 11.17  ? 27  PHE S CD1   1 
ATOM   7060 C CD2   . PHE E 4 27  ? 131.958 88.961  93.552  1.00 11.17  ? 27  PHE S CD2   1 
ATOM   7061 C CE1   . PHE E 4 27  ? 133.831 86.963  93.304  1.00 11.17  ? 27  PHE S CE1   1 
ATOM   7062 C CE2   . PHE E 4 27  ? 131.885 87.847  94.359  1.00 11.17  ? 27  PHE S CE2   1 
ATOM   7063 C CZ    . PHE E 4 27  ? 132.822 86.847  94.235  1.00 11.17  ? 27  PHE S CZ    1 
ATOM   7064 N N     . ALA E 4 28  ? 132.996 92.584  93.693  1.00 11.39  ? 28  ALA S N     1 
ATOM   7065 C CA    . ALA E 4 28  ? 132.698 93.194  94.989  1.00 11.39  ? 28  ALA S CA    1 
ATOM   7066 C C     . ALA E 4 28  ? 132.053 92.137  95.880  1.00 11.39  ? 28  ALA S C     1 
ATOM   7067 O O     . ALA E 4 28  ? 130.837 92.091  96.078  1.00 11.39  ? 28  ALA S O     1 
ATOM   7068 C CB    . ALA E 4 28  ? 131.799 94.411  94.817  1.00 11.39  ? 28  ALA S CB    1 
ATOM   7069 N N     . PHE E 4 29  ? 132.905 91.282  96.448  1.00 13.25  ? 29  PHE S N     1 
ATOM   7070 C CA    . PHE E 4 29  ? 132.416 90.116  97.175  1.00 13.25  ? 29  PHE S CA    1 
ATOM   7071 C C     . PHE E 4 29  ? 131.550 90.517  98.363  1.00 13.25  ? 29  PHE S C     1 
ATOM   7072 O O     . PHE E 4 29  ? 130.510 89.899  98.617  1.00 13.25  ? 29  PHE S O     1 
ATOM   7073 C CB    . PHE E 4 29  ? 133.603 89.263  97.624  1.00 13.25  ? 29  PHE S CB    1 
ATOM   7074 C CG    . PHE E 4 29  ? 133.223 88.075  98.457  1.00 13.25  ? 29  PHE S CG    1 
ATOM   7075 C CD1   . PHE E 4 29  ? 132.817 86.895  97.860  1.00 13.25  ? 29  PHE S CD1   1 
ATOM   7076 C CD2   . PHE E 4 29  ? 133.272 88.137  99.838  1.00 13.25  ? 29  PHE S CD2   1 
ATOM   7077 C CE1   . PHE E 4 29  ? 132.470 85.801  98.625  1.00 13.25  ? 29  PHE S CE1   1 
ATOM   7078 C CE2   . PHE E 4 29  ? 132.929 87.046  100.607 1.00 13.25  ? 29  PHE S CE2   1 
ATOM   7079 C CZ    . PHE E 4 29  ? 132.524 85.877  100.000 1.00 13.25  ? 29  PHE S CZ    1 
ATOM   7080 N N     . SER E 4 30  ? 131.957 91.553  99.102  1.00 13.24  ? 30  SER S N     1 
ATOM   7081 C CA    . SER E 4 30  ? 131.218 91.951  100.295 1.00 13.24  ? 30  SER S CA    1 
ATOM   7082 C C     . SER E 4 30  ? 129.761 92.272  99.995  1.00 13.24  ? 30  SER S C     1 
ATOM   7083 O O     . SER E 4 30  ? 128.904 92.079  100.864 1.00 13.24  ? 30  SER S O     1 
ATOM   7084 C CB    . SER E 4 30  ? 131.883 93.163  100.944 1.00 13.24  ? 30  SER S CB    1 
ATOM   7085 O OG    . SER E 4 30  ? 131.795 94.301  100.105 1.00 13.24  ? 30  SER S OG    1 
ATOM   7086 N N     . SER E 4 31  ? 129.460 92.754  98.793  1.00 10.05  ? 31  SER S N     1 
ATOM   7087 C CA    . SER E 4 31  ? 128.098 93.080  98.397  1.00 10.05  ? 31  SER S CA    1 
ATOM   7088 C C     . SER E 4 31  ? 127.358 91.889  97.808  1.00 10.05  ? 31  SER S C     1 
ATOM   7089 O O     . SER E 4 31  ? 126.227 92.048  97.342  1.00 10.05  ? 31  SER S O     1 
ATOM   7090 C CB    . SER E 4 31  ? 128.106 94.229  97.387  1.00 10.05  ? 31  SER S CB    1 
ATOM   7091 O OG    . SER E 4 31  ? 128.775 93.852  96.197  1.00 10.05  ? 31  SER S OG    1 
ATOM   7092 N N     . PHE E 4 32  ? 127.967 90.706  97.817  1.00 10.34  ? 32  PHE S N     1 
ATOM   7093 C CA    . PHE E 4 32  ? 127.379 89.500  97.256  1.00 10.34  ? 32  PHE S CA    1 
ATOM   7094 C C     . PHE E 4 32  ? 127.035 88.529  98.374  1.00 10.34  ? 32  PHE S C     1 
ATOM   7095 O O     . PHE E 4 32  ? 127.863 88.269  99.253  1.00 10.34  ? 32  PHE S O     1 
ATOM   7096 C CB    . PHE E 4 32  ? 128.342 88.826  96.272  1.00 10.34  ? 32  PHE S CB    1 
ATOM   7097 C CG    . PHE E 4 32  ? 128.221 89.318  94.858  1.00 10.34  ? 32  PHE S CG    1 
ATOM   7098 C CD1   . PHE E 4 32  ? 127.344 88.717  93.975  1.00 10.34  ? 32  PHE S CD1   1 
ATOM   7099 C CD2   . PHE E 4 32  ? 128.990 90.376  94.411  1.00 10.34  ? 32  PHE S CD2   1 
ATOM   7100 C CE1   . PHE E 4 32  ? 127.239 89.164  92.674  1.00 10.34  ? 32  PHE S CE1   1 
ATOM   7101 C CE2   . PHE E 4 32  ? 128.888 90.828  93.114  1.00 10.34  ? 32  PHE S CE2   1 
ATOM   7102 C CZ    . PHE E 4 32  ? 128.011 90.223  92.245  1.00 10.34  ? 32  PHE S CZ    1 
ATOM   7103 N N     . GLY E 4 33  ? 125.812 88.009  98.344  1.00 11.52  ? 33  GLY S N     1 
ATOM   7104 C CA    . GLY E 4 33  ? 125.498 86.820  99.101  1.00 11.52  ? 33  GLY S CA    1 
ATOM   7105 C C     . GLY E 4 33  ? 126.087 85.583  98.454  1.00 11.52  ? 33  GLY S C     1 
ATOM   7106 O O     . GLY E 4 33  ? 126.454 85.582  97.281  1.00 11.52  ? 33  GLY S O     1 
ATOM   7107 N N     . MET E 4 34  ? 126.181 84.507  99.228  1.00 12.31  ? 34  MET S N     1 
ATOM   7108 C CA    . MET E 4 34  ? 126.783 83.268  98.758  1.00 12.31  ? 34  MET S CA    1 
ATOM   7109 C C     . MET E 4 34  ? 125.842 82.098  98.998  1.00 12.31  ? 34  MET S C     1 
ATOM   7110 O O     . MET E 4 34  ? 125.203 82.009  100.051 1.00 12.31  ? 34  MET S O     1 
ATOM   7111 C CB    . MET E 4 34  ? 128.121 83.012  99.449  1.00 12.31  ? 34  MET S CB    1 
ATOM   7112 C CG    . MET E 4 34  ? 129.117 84.152  99.316  1.00 12.31  ? 34  MET S CG    1 
ATOM   7113 S SD    . MET E 4 34  ? 129.462 84.592  97.601  1.00 12.31  ? 34  MET S SD    1 
ATOM   7114 C CE    . MET E 4 34  ? 130.354 83.142  97.045  1.00 12.31  ? 34  MET S CE    1 
ATOM   7115 N N     . HIS E 4 35  ? 125.760 81.211  98.014  1.00 12.05  ? 35  HIS S N     1 
ATOM   7116 C CA    . HIS E 4 35  ? 125.054 79.946  98.126  1.00 12.05  ? 35  HIS S CA    1 
ATOM   7117 C C     . HIS E 4 35  ? 126.046 78.794  98.049  1.00 12.05  ? 35  HIS S C     1 
ATOM   7118 O O     . HIS E 4 35  ? 127.035 78.845  97.309  1.00 12.05  ? 35  HIS S O     1 
ATOM   7119 C CB    . HIS E 4 35  ? 124.012 79.787  97.018  1.00 12.05  ? 35  HIS S CB    1 
ATOM   7120 C CG    . HIS E 4 35  ? 122.909 80.797  97.072  1.00 12.05  ? 35  HIS S CG    1 
ATOM   7121 N ND1   . HIS E 4 35  ? 121.719 80.567  97.727  1.00 12.05  ? 35  HIS S ND1   1 
ATOM   7122 C CD2   . HIS E 4 35  ? 122.811 82.037  96.539  1.00 12.05  ? 35  HIS S CD2   1 
ATOM   7123 C CE1   . HIS E 4 35  ? 120.938 81.624  97.601  1.00 12.05  ? 35  HIS S CE1   1 
ATOM   7124 N NE2   . HIS E 4 35  ? 121.577 82.530  96.884  1.00 12.05  ? 35  HIS S NE2   1 
ATOM   7125 N N     . TRP E 4 36  ? 125.776 77.758  98.833  1.00 15.97  ? 36  TRP S N     1 
ATOM   7126 C CA    . TRP E 4 36  ? 126.476 76.487  98.742  1.00 15.97  ? 36  TRP S CA    1 
ATOM   7127 C C     . TRP E 4 36  ? 125.503 75.482  98.151  1.00 15.97  ? 36  TRP S C     1 
ATOM   7128 O O     . TRP E 4 36  ? 124.409 75.287  98.694  1.00 15.97  ? 36  TRP S O     1 
ATOM   7129 C CB    . TRP E 4 36  ? 126.965 76.018  100.111 1.00 15.97  ? 36  TRP S CB    1 
ATOM   7130 C CG    . TRP E 4 36  ? 128.326 76.512  100.483 1.00 15.97  ? 36  TRP S CG    1 
ATOM   7131 C CD1   . TRP E 4 36  ? 128.625 77.443  101.430 1.00 15.97  ? 36  TRP S CD1   1 
ATOM   7132 C CD2   . TRP E 4 36  ? 129.577 76.091  99.926  1.00 15.97  ? 36  TRP S CD2   1 
ATOM   7133 N NE1   . TRP E 4 36  ? 129.981 77.634  101.496 1.00 15.97  ? 36  TRP S NE1   1 
ATOM   7134 C CE2   . TRP E 4 36  ? 130.590 76.815  100.583 1.00 15.97  ? 36  TRP S CE2   1 
ATOM   7135 C CE3   . TRP E 4 36  ? 129.939 75.175  98.935  1.00 15.97  ? 36  TRP S CE3   1 
ATOM   7136 C CZ2   . TRP E 4 36  ? 131.939 76.653  100.283 1.00 15.97  ? 36  TRP S CZ2   1 
ATOM   7137 C CZ3   . TRP E 4 36  ? 131.280 75.015  98.638  1.00 15.97  ? 36  TRP S CZ3   1 
ATOM   7138 C CH2   . TRP E 4 36  ? 132.263 75.750  99.310  1.00 15.97  ? 36  TRP S CH2   1 
ATOM   7139 N N     . VAL E 4 37  ? 125.900 74.858  97.043  1.00 17.04  ? 37  VAL S N     1 
ATOM   7140 C CA    . VAL E 4 37  ? 125.085 73.880  96.337  1.00 17.04  ? 37  VAL S CA    1 
ATOM   7141 C C     . VAL E 4 37  ? 125.894 72.592  96.267  1.00 17.04  ? 37  VAL S C     1 
ATOM   7142 O O     . VAL E 4 37  ? 127.094 72.581  96.533  1.00 17.04  ? 37  VAL S O     1 
ATOM   7143 C CB    . VAL E 4 37  ? 124.689 74.385  94.930  1.00 17.04  ? 37  VAL S CB    1 
ATOM   7144 C CG1   . VAL E 4 37  ? 124.003 73.304  94.114  1.00 17.04  ? 37  VAL S CG1   1 
ATOM   7145 C CG2   . VAL E 4 37  ? 123.795 75.608  95.043  1.00 17.04  ? 37  VAL S CG2   1 
ATOM   7146 N N     . ARG E 4 38  ? 125.227 71.489  95.934  1.00 23.25  ? 38  ARG S N     1 
ATOM   7147 C CA    . ARG E 4 38  ? 125.930 70.226  95.772  1.00 23.25  ? 38  ARG S CA    1 
ATOM   7148 C C     . ARG E 4 38  ? 125.271 69.400  94.679  1.00 23.25  ? 38  ARG S C     1 
ATOM   7149 O O     . ARG E 4 38  ? 124.086 69.557  94.377  1.00 23.25  ? 38  ARG S O     1 
ATOM   7150 C CB    . ARG E 4 38  ? 125.979 69.441  97.091  1.00 23.25  ? 38  ARG S CB    1 
ATOM   7151 C CG    . ARG E 4 38  ? 124.823 68.489  97.326  1.00 23.25  ? 38  ARG S CG    1 
ATOM   7152 C CD    . ARG E 4 38  ? 124.820 68.001  98.766  1.00 23.25  ? 38  ARG S CD    1 
ATOM   7153 N NE    . ARG E 4 38  ? 123.678 67.148  99.069  1.00 23.25  ? 38  ARG S NE    1 
ATOM   7154 C CZ    . ARG E 4 38  ? 123.438 66.613  100.259 1.00 23.25  ? 38  ARG S CZ    1 
ATOM   7155 N NH1   . ARG E 4 38  ? 124.238 66.831  101.289 1.00 23.25  ? 38  ARG S NH1   1 
ATOM   7156 N NH2   . ARG E 4 38  ? 122.368 65.841  100.418 1.00 23.25  ? 38  ARG S NH2   1 
ATOM   7157 N N     . GLN E 4 39  ? 126.070 68.517  94.083  1.00 25.26  ? 39  GLN S N     1 
ATOM   7158 C CA    . GLN E 4 39  ? 125.607 67.586  93.062  1.00 25.26  ? 39  GLN S CA    1 
ATOM   7159 C C     . GLN E 4 39  ? 126.141 66.204  93.398  1.00 25.26  ? 39  GLN S C     1 
ATOM   7160 O O     . GLN E 4 39  ? 127.358 66.000  93.425  1.00 25.26  ? 39  GLN S O     1 
ATOM   7161 C CB    . GLN E 4 39  ? 126.073 68.008  91.666  1.00 25.26  ? 39  GLN S CB    1 
ATOM   7162 C CG    . GLN E 4 39  ? 125.634 67.059  90.563  1.00 25.26  ? 39  GLN S CG    1 
ATOM   7163 C CD    . GLN E 4 39  ? 125.939 67.586  89.177  1.00 25.26  ? 39  GLN S CD    1 
ATOM   7164 O OE1   . GLN E 4 39  ? 125.037 67.805  88.371  1.00 25.26  ? 39  GLN S OE1   1 
ATOM   7165 N NE2   . GLN E 4 39  ? 127.219 67.784  88.890  1.00 25.26  ? 39  GLN S NE2   1 
ATOM   7166 N N     . ALA E 4 40  ? 125.240 65.267  93.664  1.00 33.18  ? 40  ALA S N     1 
ATOM   7167 C CA    . ALA E 4 40  ? 125.641 63.898  93.931  1.00 33.18  ? 40  ALA S CA    1 
ATOM   7168 C C     . ALA E 4 40  ? 126.018 63.197  92.631  1.00 33.18  ? 40  ALA S C     1 
ATOM   7169 O O     . ALA E 4 40  ? 125.572 63.593  91.551  1.00 33.18  ? 40  ALA S O     1 
ATOM   7170 C CB    . ALA E 4 40  ? 124.515 63.146  94.631  1.00 33.18  ? 40  ALA S CB    1 
ATOM   7171 N N     . PRO E 4 41  ? 126.846 62.148  92.706  1.00 38.19  ? 41  PRO S N     1 
ATOM   7172 C CA    . PRO E 4 41  ? 127.283 61.469  91.478  1.00 38.19  ? 41  PRO S CA    1 
ATOM   7173 C C     . PRO E 4 41  ? 126.129 61.106  90.557  1.00 38.19  ? 41  PRO S C     1 
ATOM   7174 O O     . PRO E 4 41  ? 125.292 60.264  90.895  1.00 38.19  ? 41  PRO S O     1 
ATOM   7175 C CB    . PRO E 4 41  ? 127.992 60.218  92.007  1.00 38.19  ? 41  PRO S CB    1 
ATOM   7176 C CG    . PRO E 4 41  ? 128.486 60.610  93.353  1.00 38.19  ? 41  PRO S CG    1 
ATOM   7177 C CD    . PRO E 4 41  ? 127.472 61.571  93.909  1.00 38.19  ? 41  PRO S CD    1 
ATOM   7178 N N     . GLU E 4 42  ? 126.089 61.747  89.387  1.00 42.35  ? 42  GLU S N     1 
ATOM   7179 C CA    . GLU E 4 42  ? 125.077 61.489  88.359  1.00 42.35  ? 42  GLU S CA    1 
ATOM   7180 C C     . GLU E 4 42  ? 123.682 61.326  88.959  1.00 42.35  ? 42  GLU S C     1 
ATOM   7181 O O     . GLU E 4 42  ? 122.940 60.404  88.616  1.00 42.35  ? 42  GLU S O     1 
ATOM   7182 C CB    . GLU E 4 42  ? 125.454 60.268  87.513  1.00 42.35  ? 42  GLU S CB    1 
ATOM   7183 C CG    . GLU E 4 42  ? 125.497 58.937  88.262  1.00 42.35  ? 42  GLU S CG    1 
ATOM   7184 C CD    . GLU E 4 42  ? 126.881 58.592  88.786  1.00 42.35  ? 42  GLU S CD    1 
ATOM   7185 O OE1   . GLU E 4 42  ? 127.840 59.340  88.499  1.00 42.35  ? 42  GLU S OE1   1 
ATOM   7186 O OE2   . GLU E 4 42  ? 127.010 57.567  89.489  1.00 42.35  ? 42  GLU S OE2   1 
ATOM   7187 N N     . LYS E 4 43  ? 123.319 62.232  89.865  1.00 37.64  ? 43  LYS S N     1 
ATOM   7188 C CA    . LYS E 4 43  ? 121.974 62.260  90.431  1.00 37.64  ? 43  LYS S CA    1 
ATOM   7189 C C     . LYS E 4 43  ? 121.324 63.633  90.381  1.00 37.64  ? 43  LYS S C     1 
ATOM   7190 O O     . LYS E 4 43  ? 120.095 63.719  90.306  1.00 37.64  ? 43  LYS S O     1 
ATOM   7191 C CB    . LYS E 4 43  ? 121.994 61.753  91.883  1.00 37.64  ? 43  LYS S CB    1 
ATOM   7192 C CG    . LYS E 4 43  ? 122.174 60.243  91.994  1.00 37.64  ? 43  LYS S CG    1 
ATOM   7193 C CD    . LYS E 4 43  ? 121.798 59.715  93.372  1.00 37.64  ? 43  LYS S CD    1 
ATOM   7194 C CE    . LYS E 4 43  ? 122.765 60.186  94.444  1.00 37.64  ? 43  LYS S CE    1 
ATOM   7195 N NZ    . LYS E 4 43  ? 122.416 59.647  95.788  1.00 37.64  ? 43  LYS S NZ    1 
ATOM   7196 N N     . GLY E 4 44  ? 122.105 64.712  90.425  1.00 28.56  ? 44  GLY S N     1 
ATOM   7197 C CA    . GLY E 4 44  ? 121.552 66.044  90.255  1.00 28.56  ? 44  GLY S CA    1 
ATOM   7198 C C     . GLY E 4 44  ? 121.997 67.056  91.292  1.00 28.56  ? 44  GLY S C     1 
ATOM   7199 O O     . GLY E 4 44  ? 122.632 66.702  92.288  1.00 28.56  ? 44  GLY S O     1 
ATOM   7200 N N     . LEU E 4 45  ? 121.654 68.322  91.065  1.00 21.85  ? 45  LEU S N     1 
ATOM   7201 C CA    . LEU E 4 45  ? 122.030 69.402  91.966  1.00 21.85  ? 45  LEU S CA    1 
ATOM   7202 C C     . LEU E 4 45  ? 121.110 69.446  93.181  1.00 21.85  ? 45  LEU S C     1 
ATOM   7203 O O     . LEU E 4 45  ? 119.911 69.167  93.093  1.00 21.85  ? 45  LEU S O     1 
ATOM   7204 C CB    . LEU E 4 45  ? 121.981 70.746  91.239  1.00 21.85  ? 45  LEU S CB    1 
ATOM   7205 C CG    . LEU E 4 45  ? 123.207 71.115  90.403  1.00 21.85  ? 45  LEU S CG    1 
ATOM   7206 C CD1   . LEU E 4 45  ? 123.457 70.067  89.346  1.00 21.85  ? 45  LEU S CD1   1 
ATOM   7207 C CD2   . LEU E 4 45  ? 123.017 72.476  89.761  1.00 21.85  ? 45  LEU S CD2   1 
ATOM   7208 N N     . GLU E 4 46  ? 121.687 69.808  94.325  1.00 21.27  ? 46  GLU S N     1 
ATOM   7209 C CA    . GLU E 4 46  ? 120.932 69.924  95.569  1.00 21.27  ? 46  GLU S CA    1 
ATOM   7210 C C     . GLU E 4 46  ? 121.484 71.096  96.366  1.00 21.27  ? 46  GLU S C     1 
ATOM   7211 O O     . GLU E 4 46  ? 122.675 71.121  96.688  1.00 21.27  ? 46  GLU S O     1 
ATOM   7212 C CB    . GLU E 4 46  ? 121.012 68.630  96.383  1.00 21.27  ? 46  GLU S CB    1 
ATOM   7213 C CG    . GLU E 4 46  ? 120.226 68.667  97.683  1.00 21.27  ? 46  GLU S CG    1 
ATOM   7214 C CD    . GLU E 4 46  ? 120.261 67.346  98.423  1.00 21.27  ? 46  GLU S CD    1 
ATOM   7215 O OE1   . GLU E 4 46  ? 120.856 66.384  97.896  1.00 21.27  ? 46  GLU S OE1   1 
ATOM   7216 O OE2   . GLU E 4 46  ? 119.696 67.271  99.533  1.00 21.27  ? 46  GLU S OE2   1 
ATOM   7217 N N     . TRP E 4 47  ? 120.619 72.059  96.679  1.00 16.62  ? 47  TRP S N     1 
ATOM   7218 C CA    . TRP E 4 47  ? 121.035 73.215  97.461  1.00 16.62  ? 47  TRP S CA    1 
ATOM   7219 C C     . TRP E 4 47  ? 121.471 72.785  98.856  1.00 16.62  ? 47  TRP S C     1 
ATOM   7220 O O     . TRP E 4 47  ? 120.894 71.870  99.450  1.00 16.62  ? 47  TRP S O     1 
ATOM   7221 C CB    . TRP E 4 47  ? 119.891 74.225  97.556  1.00 16.62  ? 47  TRP S CB    1 
ATOM   7222 C CG    . TRP E 4 47  ? 120.197 75.399  98.429  1.00 16.62  ? 47  TRP S CG    1 
ATOM   7223 C CD1   . TRP E 4 47  ? 121.130 76.367  98.202  1.00 16.62  ? 47  TRP S CD1   1 
ATOM   7224 C CD2   . TRP E 4 47  ? 119.566 75.734  99.672  1.00 16.62  ? 47  TRP S CD2   1 
ATOM   7225 N NE1   . TRP E 4 47  ? 121.120 77.282  99.225  1.00 16.62  ? 47  TRP S NE1   1 
ATOM   7226 C CE2   . TRP E 4 47  ? 120.169 76.916  100.140 1.00 16.62  ? 47  TRP S CE2   1 
ATOM   7227 C CE3   . TRP E 4 47  ? 118.551 75.148  100.433 1.00 16.62  ? 47  TRP S CE3   1 
ATOM   7228 C CZ2   . TRP E 4 47  ? 119.790 77.523  101.334 1.00 16.62  ? 47  TRP S CZ2   1 
ATOM   7229 C CZ3   . TRP E 4 47  ? 118.178 75.754  101.619 1.00 16.62  ? 47  TRP S CZ3   1 
ATOM   7230 C CH2   . TRP E 4 47  ? 118.795 76.928  102.056 1.00 16.62  ? 47  TRP S CH2   1 
ATOM   7231 N N     . VAL E 4 48  ? 122.499 73.454  99.382  1.00 17.87  ? 48  VAL S N     1 
ATOM   7232 C CA    . VAL E 4 48  ? 123.056 73.134  100.687 1.00 17.87  ? 48  VAL S CA    1 
ATOM   7233 C C     . VAL E 4 48  ? 122.811 74.244  101.700 1.00 17.87  ? 48  VAL S C     1 
ATOM   7234 O O     . VAL E 4 48  ? 122.397 73.971  102.832 1.00 17.87  ? 48  VAL S O     1 
ATOM   7235 C CB    . VAL E 4 48  ? 124.565 72.821  100.587 1.00 17.87  ? 48  VAL S CB    1 
ATOM   7236 C CG1   . VAL E 4 48  ? 125.203 72.821  101.965 1.00 17.87  ? 48  VAL S CG1   1 
ATOM   7237 C CG2   . VAL E 4 48  ? 124.783 71.489  99.903  1.00 17.87  ? 48  VAL S CG2   1 
ATOM   7238 N N     . ALA E 4 49  ? 123.060 75.497  101.328 1.00 15.11  ? 49  ALA S N     1 
ATOM   7239 C CA    . ALA E 4 49  ? 122.942 76.577  102.303 1.00 15.11  ? 49  ALA S CA    1 
ATOM   7240 C C     . ALA E 4 49  ? 123.064 77.926  101.610 1.00 15.11  ? 49  ALA S C     1 
ATOM   7241 O O     . ALA E 4 49  ? 123.369 78.006  100.417 1.00 15.11  ? 49  ALA S O     1 
ATOM   7242 C CB    . ALA E 4 49  ? 124.003 76.453  103.401 1.00 15.11  ? 49  ALA S CB    1 
ATOM   7243 N N     . TYR E 4 50  ? 122.849 78.987  102.389 1.00 12.07  ? 50  TYR S N     1 
ATOM   7244 C CA    . TYR E 4 50  ? 122.902 80.354  101.889 1.00 12.07  ? 50  TYR S CA    1 
ATOM   7245 C C     . TYR E 4 50  ? 123.275 81.303  103.019 1.00 12.07  ? 50  TYR S C     1 
ATOM   7246 O O     . TYR E 4 50  ? 122.841 81.121  104.158 1.00 12.07  ? 50  TYR S O     1 
ATOM   7247 C CB    . TYR E 4 50  ? 121.551 80.762  101.281 1.00 12.07  ? 50  TYR S CB    1 
ATOM   7248 C CG    . TYR E 4 50  ? 121.377 82.250  101.076 1.00 12.07  ? 50  TYR S CG    1 
ATOM   7249 C CD1   . TYR E 4 50  ? 122.293 82.983  100.336 1.00 12.07  ? 50  TYR S CD1   1 
ATOM   7250 C CD2   . TYR E 4 50  ? 120.290 82.920  101.617 1.00 12.07  ? 50  TYR S CD2   1 
ATOM   7251 C CE1   . TYR E 4 50  ? 122.134 84.340  100.144 1.00 12.07  ? 50  TYR S CE1   1 
ATOM   7252 C CE2   . TYR E 4 50  ? 120.123 84.276  101.430 1.00 12.07  ? 50  TYR S CE2   1 
ATOM   7253 C CZ    . TYR E 4 50  ? 121.048 84.981  100.693 1.00 12.07  ? 50  TYR S CZ    1 
ATOM   7254 O OH    . TYR E 4 50  ? 120.886 86.333  100.504 1.00 12.07  ? 50  TYR S OH    1 
ATOM   7255 N N     . ILE E 4 51  ? 124.086 82.311  102.701 1.00 12.41  ? 51  ILE S N     1 
ATOM   7256 C CA    . ILE E 4 51  ? 124.418 83.390  103.626 1.00 12.41  ? 51  ILE S CA    1 
ATOM   7257 C C     . ILE E 4 51  ? 124.347 84.709  102.868 1.00 12.41  ? 51  ILE S C     1 
ATOM   7258 O O     . ILE E 4 51  ? 124.997 84.867  101.830 1.00 12.41  ? 51  ILE S O     1 
ATOM   7259 C CB    . ILE E 4 51  ? 125.811 83.196  104.260 1.00 12.41  ? 51  ILE S CB    1 
ATOM   7260 C CG1   . ILE E 4 51  ? 126.114 84.337  105.231 1.00 12.41  ? 51  ILE S CG1   1 
ATOM   7261 C CG2   . ILE E 4 51  ? 126.890 83.099  103.191 1.00 12.41  ? 51  ILE S CG2   1 
ATOM   7262 C CD1   . ILE E 4 51  ? 127.150 83.990  106.267 1.00 12.41  ? 51  ILE S CD1   1 
ATOM   7263 N N     . SER E 4 52  ? 123.581 85.659  103.393 1.00 11.10  ? 52  SER S N     1 
ATOM   7264 C CA    . SER E 4 52  ? 123.332 86.908  102.690 1.00 11.10  ? 52  SER S CA    1 
ATOM   7265 C C     . SER E 4 52  ? 124.476 87.896  102.902 1.00 11.10  ? 52  SER S C     1 
ATOM   7266 O O     . SER E 4 52  ? 125.389 87.676  103.701 1.00 11.10  ? 52  SER S O     1 
ATOM   7267 C CB    . SER E 4 52  ? 122.015 87.530  103.151 1.00 11.10  ? 52  SER S CB    1 
ATOM   7268 O OG    . SER E 4 52  ? 122.193 88.259  104.351 1.00 11.10  ? 52  SER S OG    1 
ATOM   7269 N N     . SER E 4 53  ? 124.416 89.002  102.165 1.00 11.94  ? 53  SER S N     1 
ATOM   7270 C CA    . SER E 4 53  ? 125.420 90.049  102.297 1.00 11.94  ? 53  SER S CA    1 
ATOM   7271 C C     . SER E 4 53  ? 125.286 90.732  103.652 1.00 11.94  ? 53  SER S C     1 
ATOM   7272 O O     . SER E 4 53  ? 124.255 91.341  103.952 1.00 11.94  ? 53  SER S O     1 
ATOM   7273 C CB    . SER E 4 53  ? 125.268 91.067  101.170 1.00 11.94  ? 53  SER S CB    1 
ATOM   7274 O OG    . SER E 4 53  ? 124.136 91.891  101.382 1.00 11.94  ? 53  SER S OG    1 
ATOM   7275 N N     . GLY E 4 54  ? 126.334 90.634  104.465 1.00 12.79  ? 54  GLY S N     1 
ATOM   7276 C CA    . GLY E 4 54  ? 126.316 91.155  105.814 1.00 12.79  ? 54  GLY S CA    1 
ATOM   7277 C C     . GLY E 4 54  ? 126.075 90.118  106.888 1.00 12.79  ? 54  GLY S C     1 
ATOM   7278 O O     . GLY E 4 54  ? 126.020 90.479  108.069 1.00 12.79  ? 54  GLY S O     1 
ATOM   7279 N N     . SER E 4 55  ? 125.926 88.847  106.519 1.00 12.01  ? 55  SER S N     1 
ATOM   7280 C CA    . SER E 4 55  ? 125.716 87.758  107.468 1.00 12.01  ? 55  SER S CA    1 
ATOM   7281 C C     . SER E 4 55  ? 124.424 87.920  108.260 1.00 12.01  ? 55  SER S C     1 
ATOM   7282 O O     . SER E 4 55  ? 124.236 87.263  109.288 1.00 12.01  ? 55  SER S O     1 
ATOM   7283 C CB    . SER E 4 55  ? 126.904 87.632  108.428 1.00 12.01  ? 55  SER S CB    1 
ATOM   7284 O OG    . SER E 4 55  ? 128.124 87.525  107.718 1.00 12.01  ? 55  SER S OG    1 
ATOM   7285 N N     . GLY E 4 56  ? 123.517 88.784  107.798 1.00 11.78  ? 56  GLY S N     1 
ATOM   7286 C CA    . GLY E 4 56  ? 122.282 89.018  108.524 1.00 11.78  ? 56  GLY S CA    1 
ATOM   7287 C C     . GLY E 4 56  ? 121.240 87.937  108.354 1.00 11.78  ? 56  GLY S C     1 
ATOM   7288 O O     . GLY E 4 56  ? 120.281 87.891  109.131 1.00 11.78  ? 56  GLY S O     1 
ATOM   7289 N N     . THR E 4 57  ? 121.401 87.068  107.359 1.00 11.16  ? 57  THR S N     1 
ATOM   7290 C CA    . THR E 4 57  ? 120.451 85.991  107.084 1.00 11.16  ? 57  THR S CA    1 
ATOM   7291 C C     . THR E 4 57  ? 121.243 84.761  106.655 1.00 11.16  ? 57  THR S C     1 
ATOM   7292 O O     . THR E 4 57  ? 121.942 84.789  105.639 1.00 11.16  ? 57  THR S O     1 
ATOM   7293 C CB    . THR E 4 57  ? 119.448 86.400  106.011 1.00 11.16  ? 57  THR S CB    1 
ATOM   7294 O OG1   . THR E 4 57  ? 118.812 87.626  106.390 1.00 11.16  ? 57  THR S OG1   1 
ATOM   7295 C CG2   . THR E 4 57  ? 118.392 85.322  105.828 1.00 11.16  ? 57  THR S CG2   1 
ATOM   7296 N N     . ILE E 4 58  ? 121.137 83.688  107.434 1.00 12.68  ? 58  ILE S N     1 
ATOM   7297 C CA    . ILE E 4 58  ? 121.782 82.417  107.130 1.00 12.68  ? 58  ILE S CA    1 
ATOM   7298 C C     . ILE E 4 58  ? 120.701 81.349  107.071 1.00 12.68  ? 58  ILE S C     1 
ATOM   7299 O O     . ILE E 4 58  ? 119.958 81.152  108.040 1.00 12.68  ? 58  ILE S O     1 
ATOM   7300 C CB    . ILE E 4 58  ? 122.855 82.064  108.169 1.00 12.68  ? 58  ILE S CB    1 
ATOM   7301 C CG1   . ILE E 4 58  ? 124.019 83.054  108.079 1.00 12.68  ? 58  ILE S CG1   1 
ATOM   7302 C CG2   . ILE E 4 58  ? 123.335 80.641  107.957 1.00 12.68  ? 58  ILE S CG2   1 
ATOM   7303 C CD1   . ILE E 4 58  ? 125.043 82.905  109.179 1.00 12.68  ? 58  ILE S CD1   1 
ATOM   7304 N N     . TYR E 4 59  ? 120.617 80.657  105.938 1.00 14.12  ? 59  TYR S N     1 
ATOM   7305 C CA    . TYR E 4 59  ? 119.626 79.618  105.706 1.00 14.12  ? 59  TYR S CA    1 
ATOM   7306 C C     . TYR E 4 59  ? 120.333 78.299  105.438 1.00 14.12  ? 59  TYR S C     1 
ATOM   7307 O O     . TYR E 4 59  ? 121.402 78.273  104.818 1.00 14.12  ? 59  TYR S O     1 
ATOM   7308 C CB    . TYR E 4 59  ? 118.724 79.967  104.515 1.00 14.12  ? 59  TYR S CB    1 
ATOM   7309 C CG    . TYR E 4 59  ? 117.655 81.003  104.795 1.00 14.12  ? 59  TYR S CG    1 
ATOM   7310 C CD1   . TYR E 4 59  ? 117.421 81.476  106.080 1.00 14.12  ? 59  TYR S CD1   1 
ATOM   7311 C CD2   . TYR E 4 59  ? 116.877 81.509  103.764 1.00 14.12  ? 59  TYR S CD2   1 
ATOM   7312 C CE1   . TYR E 4 59  ? 116.444 82.419  106.327 1.00 14.12  ? 59  TYR S CE1   1 
ATOM   7313 C CE2   . TYR E 4 59  ? 115.898 82.452  104.002 1.00 14.12  ? 59  TYR S CE2   1 
ATOM   7314 C CZ    . TYR E 4 59  ? 115.685 82.903  105.285 1.00 14.12  ? 59  TYR S CZ    1 
ATOM   7315 O OH    . TYR E 4 59  ? 114.711 83.844  105.525 1.00 14.12  ? 59  TYR S OH    1 
ATOM   7316 N N     . TYR E 4 60  ? 119.724 77.207  105.893 1.00 17.28  ? 60  TYR S N     1 
ATOM   7317 C CA    . TYR E 4 60  ? 120.267 75.870  105.723 1.00 17.28  ? 60  TYR S CA    1 
ATOM   7318 C C     . TYR E 4 60  ? 119.210 74.967  105.106 1.00 17.28  ? 60  TYR S C     1 
ATOM   7319 O O     . TYR E 4 60  ? 118.008 75.211  105.238 1.00 17.28  ? 60  TYR S O     1 
ATOM   7320 C CB    . TYR E 4 60  ? 120.732 75.287  107.061 1.00 17.28  ? 60  TYR S CB    1 
ATOM   7321 C CG    . TYR E 4 60  ? 121.911 76.013  107.663 1.00 17.28  ? 60  TYR S CG    1 
ATOM   7322 C CD1   . TYR E 4 60  ? 123.187 75.868  107.137 1.00 17.28  ? 60  TYR S CD1   1 
ATOM   7323 C CD2   . TYR E 4 60  ? 121.745 76.852  108.755 1.00 17.28  ? 60  TYR S CD2   1 
ATOM   7324 C CE1   . TYR E 4 60  ? 124.263 76.536  107.685 1.00 17.28  ? 60  TYR S CE1   1 
ATOM   7325 C CE2   . TYR E 4 60  ? 122.813 77.521  109.308 1.00 17.28  ? 60  TYR S CE2   1 
ATOM   7326 C CZ    . TYR E 4 60  ? 124.068 77.363  108.770 1.00 17.28  ? 60  TYR S CZ    1 
ATOM   7327 O OH    . TYR E 4 60  ? 125.132 78.034  109.325 1.00 17.28  ? 60  TYR S OH    1 
ATOM   7328 N N     . ALA E 4 61  ? 119.670 73.923  104.422 1.00 21.34  ? 61  ALA S N     1 
ATOM   7329 C CA    . ALA E 4 61  ? 118.755 72.977  103.798 1.00 21.34  ? 61  ALA S CA    1 
ATOM   7330 C C     . ALA E 4 61  ? 118.233 71.994  104.836 1.00 21.34  ? 61  ALA S C     1 
ATOM   7331 O O     . ALA E 4 61  ? 118.984 71.533  105.702 1.00 21.34  ? 61  ALA S O     1 
ATOM   7332 C CB    . ALA E 4 61  ? 119.455 72.230  102.665 1.00 21.34  ? 61  ALA S CB    1 
ATOM   7333 N N     . ASP E 4 62  ? 116.943 71.664  104.742 1.00 27.54  ? 62  ASP S N     1 
ATOM   7334 C CA    . ASP E 4 62  ? 116.341 70.747  105.705 1.00 27.54  ? 62  ASP S CA    1 
ATOM   7335 C C     . ASP E 4 62  ? 117.128 69.446  105.789 1.00 27.54  ? 62  ASP S C     1 
ATOM   7336 O O     . ASP E 4 62  ? 117.264 68.860  106.870 1.00 27.54  ? 62  ASP S O     1 
ATOM   7337 C CB    . ASP E 4 62  ? 114.887 70.467  105.323 1.00 27.54  ? 62  ASP S CB    1 
ATOM   7338 C CG    . ASP E 4 62  ? 113.994 71.681  105.499 1.00 27.54  ? 62  ASP S CG    1 
ATOM   7339 O OD1   . ASP E 4 62  ? 114.285 72.514  106.383 1.00 27.54  ? 62  ASP S OD1   1 
ATOM   7340 O OD2   . ASP E 4 62  ? 113.000 71.802  104.752 1.00 27.54  ? 62  ASP S OD2   1 
ATOM   7341 N N     . THR E 4 63  ? 117.656 68.979  104.657 1.00 26.63  ? 63  THR S N     1 
ATOM   7342 C CA    . THR E 4 63  ? 118.457 67.760  104.664 1.00 26.63  ? 63  THR S CA    1 
ATOM   7343 C C     . THR E 4 63  ? 119.650 67.890  105.603 1.00 26.63  ? 63  THR S C     1 
ATOM   7344 O O     . THR E 4 63  ? 120.075 66.904  106.217 1.00 26.63  ? 63  THR S O     1 
ATOM   7345 C CB    . THR E 4 63  ? 118.930 67.437  103.246 1.00 26.63  ? 63  THR S CB    1 
ATOM   7346 O OG1   . THR E 4 63  ? 117.795 67.246  102.393 1.00 26.63  ? 63  THR S OG1   1 
ATOM   7347 C CG2   . THR E 4 63  ? 119.786 66.179  103.239 1.00 26.63  ? 63  THR S CG2   1 
ATOM   7348 N N     . VAL E 4 64  ? 120.211 69.092  105.718 1.00 26.50  ? 64  VAL S N     1 
ATOM   7349 C CA    . VAL E 4 64  ? 121.370 69.321  106.574 1.00 26.50  ? 64  VAL S CA    1 
ATOM   7350 C C     . VAL E 4 64  ? 121.124 70.521  107.480 1.00 26.50  ? 64  VAL S C     1 
ATOM   7351 O O     . VAL E 4 64  ? 122.072 71.130  107.985 1.00 26.50  ? 64  VAL S O     1 
ATOM   7352 C CB    . VAL E 4 64  ? 122.646 69.526  105.736 1.00 26.50  ? 64  VAL S CB    1 
ATOM   7353 C CG1   . VAL E 4 64  ? 122.948 68.283  104.917 1.00 26.50  ? 64  VAL S CG1   1 
ATOM   7354 C CG2   . VAL E 4 64  ? 122.509 70.746  104.834 1.00 26.50  ? 64  VAL S CG2   1 
ATOM   7355 N N     . LYS E 4 65  ? 119.860 70.879  107.692 1.00 23.91  ? 65  LYS S N     1 
ATOM   7356 C CA    . LYS E 4 65  ? 119.512 71.984  108.576 1.00 23.91  ? 65  LYS S CA    1 
ATOM   7357 C C     . LYS E 4 65  ? 119.805 71.556  110.008 1.00 23.91  ? 65  LYS S C     1 
ATOM   7358 O O     . LYS E 4 65  ? 119.378 70.479  110.438 1.00 23.91  ? 65  LYS S O     1 
ATOM   7359 C CB    . LYS E 4 65  ? 118.046 72.386  108.417 1.00 23.91  ? 65  LYS S CB    1 
ATOM   7360 C CG    . LYS E 4 65  ? 117.646 73.587  109.259 1.00 23.91  ? 65  LYS S CG    1 
ATOM   7361 C CD    . LYS E 4 65  ? 116.354 74.217  108.760 1.00 23.91  ? 65  LYS S CD    1 
ATOM   7362 C CE    . LYS E 4 65  ? 116.183 75.632  109.288 1.00 23.91  ? 65  LYS S CE    1 
ATOM   7363 N NZ    . LYS E 4 65  ? 117.051 76.604  108.567 1.00 23.91  ? 65  LYS S NZ    1 
ATOM   7364 N N     . GLY E 4 66  ? 120.539 72.392  110.738 1.00 28.65  ? 66  GLY S N     1 
ATOM   7365 C CA    . GLY E 4 66  ? 120.995 72.071  112.068 1.00 28.65  ? 66  GLY S CA    1 
ATOM   7366 C C     . GLY E 4 66  ? 122.287 71.283  112.105 1.00 28.65  ? 66  GLY S C     1 
ATOM   7367 O O     . GLY E 4 66  ? 122.888 71.150  113.177 1.00 28.65  ? 66  GLY S O     1 
ATOM   7368 N N     . ARG E 4 67  ? 122.726 70.761  110.962 1.00 31.65  ? 67  ARG S N     1 
ATOM   7369 C CA    . ARG E 4 67  ? 123.981 70.028  110.838 1.00 31.65  ? 67  ARG S CA    1 
ATOM   7370 C C     . ARG E 4 67  ? 124.717 70.598  109.633 1.00 31.65  ? 67  ARG S C     1 
ATOM   7371 O O     . ARG E 4 67  ? 124.307 70.364  108.493 1.00 31.65  ? 67  ARG S O     1 
ATOM   7372 C CB    . ARG E 4 67  ? 123.721 68.528  110.689 1.00 31.65  ? 67  ARG S CB    1 
ATOM   7373 C CG    . ARG E 4 67  ? 124.934 67.701  110.289 1.00 31.65  ? 67  ARG S CG    1 
ATOM   7374 C CD    . ARG E 4 67  ? 124.550 66.253  110.025 1.00 31.65  ? 67  ARG S CD    1 
ATOM   7375 N NE    . ARG E 4 67  ? 123.761 66.096  108.808 1.00 31.65  ? 67  ARG S NE    1 
ATOM   7376 C CZ    . ARG E 4 67  ? 124.172 65.483  107.704 1.00 31.65  ? 67  ARG S CZ    1 
ATOM   7377 N NH1   . ARG E 4 67  ? 125.389 64.971  107.603 1.00 31.65  ? 67  ARG S NH1   1 
ATOM   7378 N NH2   . ARG E 4 67  ? 123.340 65.379  106.673 1.00 31.65  ? 67  ARG S NH2   1 
ATOM   7379 N N     . PHE E 4 68  ? 125.814 71.317  109.902 1.00 27.57  ? 68  PHE S N     1 
ATOM   7380 C CA    . PHE E 4 68  ? 126.562 72.155  108.961 1.00 27.57  ? 68  PHE S CA    1 
ATOM   7381 C C     . PHE E 4 68  ? 126.521 73.598  109.448 1.00 27.57  ? 68  PHE S C     1 
ATOM   7382 O O     . PHE E 4 68  ? 125.655 73.963  110.249 1.00 27.57  ? 68  PHE S O     1 
ATOM   7383 C CB    . PHE E 4 68  ? 126.023 72.113  107.524 1.00 27.57  ? 68  PHE S CB    1 
ATOM   7384 C CG    . PHE E 4 68  ? 126.318 70.835  106.778 1.00 27.57  ? 68  PHE S CG    1 
ATOM   7385 C CD1   . PHE E 4 68  ? 126.926 69.759  107.402 1.00 27.57  ? 68  PHE S CD1   1 
ATOM   7386 C CD2   . PHE E 4 68  ? 125.973 70.717  105.442 1.00 27.57  ? 68  PHE S CD2   1 
ATOM   7387 C CE1   . PHE E 4 68  ? 127.183 68.595  106.706 1.00 27.57  ? 68  PHE S CE1   1 
ATOM   7388 C CE2   . PHE E 4 68  ? 126.230 69.558  104.744 1.00 27.57  ? 68  PHE S CE2   1 
ATOM   7389 C CZ    . PHE E 4 68  ? 126.837 68.496  105.376 1.00 27.57  ? 68  PHE S CZ    1 
ATOM   7390 N N     . THR E 4 69  ? 127.452 74.424  108.976 1.00 22.80  ? 69  THR S N     1 
ATOM   7391 C CA    . THR E 4 69  ? 127.387 75.857  109.225 1.00 22.80  ? 69  THR S CA    1 
ATOM   7392 C C     . THR E 4 69  ? 128.093 76.594  108.094 1.00 22.80  ? 69  THR S C     1 
ATOM   7393 O O     . THR E 4 69  ? 129.080 76.109  107.539 1.00 22.80  ? 69  THR S O     1 
ATOM   7394 C CB    . THR E 4 69  ? 127.998 76.233  110.582 1.00 22.80  ? 69  THR S CB    1 
ATOM   7395 O OG1   . THR E 4 69  ? 127.830 77.637  110.813 1.00 22.80  ? 69  THR S OG1   1 
ATOM   7396 C CG2   . THR E 4 69  ? 129.474 75.883  110.635 1.00 22.80  ? 69  THR S CG2   1 
ATOM   7397 N N     . ILE E 4 70  ? 127.570 77.770  107.753 1.00 15.60  ? 70  ILE S N     1 
ATOM   7398 C CA    . ILE E 4 70  ? 128.084 78.585  106.655 1.00 15.60  ? 70  ILE S CA    1 
ATOM   7399 C C     . ILE E 4 70  ? 128.584 79.899  107.238 1.00 15.60  ? 70  ILE S C     1 
ATOM   7400 O O     . ILE E 4 70  ? 127.844 80.592  107.947 1.00 15.60  ? 70  ILE S O     1 
ATOM   7401 C CB    . ILE E 4 70  ? 127.016 78.826  105.573 1.00 15.60  ? 70  ILE S CB    1 
ATOM   7402 C CG1   . ILE E 4 70  ? 127.625 79.554  104.373 1.00 15.60  ? 70  ILE S CG1   1 
ATOM   7403 C CG2   . ILE E 4 70  ? 125.846 79.618  106.130 1.00 15.60  ? 70  ILE S CG2   1 
ATOM   7404 C CD1   . ILE E 4 70  ? 126.683 79.682  103.199 1.00 15.60  ? 70  ILE S CD1   1 
ATOM   7405 N N     . SER E 4 71  ? 129.835 80.244  106.938 1.00 16.69  ? 71  SER S N     1 
ATOM   7406 C CA    . SER E 4 71  ? 130.505 81.389  107.542 1.00 16.69  ? 71  SER S CA    1 
ATOM   7407 C C     . SER E 4 71  ? 131.074 82.300  106.462 1.00 16.69  ? 71  SER S C     1 
ATOM   7408 O O     . SER E 4 71  ? 131.611 81.824  105.457 1.00 16.69  ? 71  SER S O     1 
ATOM   7409 C CB    . SER E 4 71  ? 131.622 80.930  108.482 1.00 16.69  ? 71  SER S CB    1 
ATOM   7410 O OG    . SER E 4 71  ? 132.509 81.994  108.777 1.00 16.69  ? 71  SER S OG    1 
ATOM   7411 N N     . ARG E 4 72  ? 130.971 83.605  106.689 1.00 15.74  ? 72  ARG S N     1 
ATOM   7412 C CA    . ARG E 4 72  ? 131.462 84.629  105.779 1.00 15.74  ? 72  ARG S CA    1 
ATOM   7413 C C     . ARG E 4 72  ? 132.754 85.241  106.317 1.00 15.74  ? 72  ARG S C     1 
ATOM   7414 O O     . ARG E 4 72  ? 132.968 85.331  107.528 1.00 15.74  ? 72  ARG S O     1 
ATOM   7415 C CB    . ARG E 4 72  ? 130.406 85.724  105.605 1.00 15.74  ? 72  ARG S CB    1 
ATOM   7416 C CG    . ARG E 4 72  ? 130.815 86.868  104.694 1.00 15.74  ? 72  ARG S CG    1 
ATOM   7417 C CD    . ARG E 4 72  ? 130.884 86.437  103.251 1.00 15.74  ? 72  ARG S CD    1 
ATOM   7418 N NE    . ARG E 4 72  ? 129.557 86.098  102.754 1.00 15.74  ? 72  ARG S NE    1 
ATOM   7419 C CZ    . ARG E 4 72  ? 128.682 86.988  102.307 1.00 15.74  ? 72  ARG S CZ    1 
ATOM   7420 N NH1   . ARG E 4 72  ? 128.974 88.276  102.240 1.00 15.74  ? 72  ARG S NH1   1 
ATOM   7421 N NH2   . ARG E 4 72  ? 127.480 86.577  101.920 1.00 15.74  ? 72  ARG S NH2   1 
ATOM   7422 N N     . ASP E 4 73  ? 133.632 85.672  105.389 1.00 20.83  ? 73  ASP S N     1 
ATOM   7423 C CA    . ASP E 4 73  ? 134.788 86.505  105.732 1.00 20.83  ? 73  ASP S CA    1 
ATOM   7424 C C     . ASP E 4 73  ? 134.919 87.554  104.625 1.00 20.83  ? 73  ASP S C     1 
ATOM   7425 O O     . ASP E 4 73  ? 135.614 87.351  103.624 1.00 20.83  ? 73  ASP S O     1 
ATOM   7426 C CB    . ASP E 4 73  ? 136.059 85.672  105.882 1.00 20.83  ? 73  ASP S CB    1 
ATOM   7427 C CG    . ASP E 4 73  ? 137.128 86.377  106.696 1.00 20.83  ? 73  ASP S CG    1 
ATOM   7428 O OD1   . ASP E 4 73  ? 136.887 87.520  107.140 1.00 20.83  ? 73  ASP S OD1   1 
ATOM   7429 O OD2   . ASP E 4 73  ? 138.212 85.788  106.890 1.00 20.83  ? 73  ASP S OD2   1 
ATOM   7430 N N     . ASP E 4 74  ? 134.234 88.682  104.811 1.00 19.00  ? 74  ASP S N     1 
ATOM   7431 C CA    . ASP E 4 74  ? 134.279 89.744  103.810 1.00 19.00  ? 74  ASP S CA    1 
ATOM   7432 C C     . ASP E 4 74  ? 135.665 90.355  103.654 1.00 19.00  ? 74  ASP S C     1 
ATOM   7433 O O     . ASP E 4 74  ? 136.117 90.502  102.505 1.00 19.00  ? 74  ASP S O     1 
ATOM   7434 C CB    . ASP E 4 74  ? 133.246 90.825  104.156 1.00 19.00  ? 74  ASP S CB    1 
ATOM   7435 C CG    . ASP E 4 74  ? 131.825 90.402  103.834 1.00 19.00  ? 74  ASP S CG    1 
ATOM   7436 O OD1   . ASP E 4 74  ? 131.649 89.455  103.042 1.00 19.00  ? 74  ASP S OD1   1 
ATOM   7437 O OD2   . ASP E 4 74  ? 130.883 91.018  104.372 1.00 19.00  ? 74  ASP S OD2   1 
ATOM   7438 N N     . PRO E 4 75  ? 136.379 90.731  104.719 1.00 22.64  ? 75  PRO S N     1 
ATOM   7439 C CA    . PRO E 4 75  ? 137.713 91.322  104.528 1.00 22.64  ? 75  PRO S CA    1 
ATOM   7440 C C     . PRO E 4 75  ? 138.679 90.417  103.788 1.00 22.64  ? 75  PRO S C     1 
ATOM   7441 O O     . PRO E 4 75  ? 139.529 90.922  103.044 1.00 22.64  ? 75  PRO S O     1 
ATOM   7442 C CB    . PRO E 4 75  ? 138.186 91.589  105.963 1.00 22.64  ? 75  PRO S CB    1 
ATOM   7443 C CG    . PRO E 4 75  ? 136.933 91.701  106.755 1.00 22.64  ? 75  PRO S CG    1 
ATOM   7444 C CD    . PRO E 4 75  ? 135.994 90.711  106.140 1.00 22.64  ? 75  PRO S CD    1 
ATOM   7445 N N     . LYS E 4 76  ? 138.582 89.099  103.965 1.00 23.10  ? 76  LYS S N     1 
ATOM   7446 C CA    . LYS E 4 76  ? 139.432 88.157  103.252 1.00 23.10  ? 76  LYS S CA    1 
ATOM   7447 C C     . LYS E 4 76  ? 138.774 87.579  102.008 1.00 23.10  ? 76  LYS S C     1 
ATOM   7448 O O     . LYS E 4 76  ? 139.390 86.744  101.337 1.00 23.10  ? 76  LYS S O     1 
ATOM   7449 C CB    . LYS E 4 76  ? 139.852 87.010  104.183 1.00 23.10  ? 76  LYS S CB    1 
ATOM   7450 C CG    . LYS E 4 76  ? 140.746 87.455  105.329 1.00 23.10  ? 76  LYS S CG    1 
ATOM   7451 C CD    . LYS E 4 76  ? 141.893 86.483  105.560 1.00 23.10  ? 76  LYS S CD    1 
ATOM   7452 C CE    . LYS E 4 76  ? 142.902 87.040  106.551 1.00 23.10  ? 76  LYS S CE    1 
ATOM   7453 N NZ    . LYS E 4 76  ? 142.307 87.253  107.899 1.00 23.10  ? 76  LYS S NZ    1 
ATOM   7454 N N     . ASN E 4 77  ? 137.555 88.000  101.681 1.00 19.84  ? 77  ASN S N     1 
ATOM   7455 C CA    . ASN E 4 77  ? 136.861 87.565  100.471 1.00 19.84  ? 77  ASN S CA    1 
ATOM   7456 C C     . ASN E 4 77  ? 136.794 86.037  100.404 1.00 19.84  ? 77  ASN S C     1 
ATOM   7457 O O     . ASN E 4 77  ? 137.166 85.409  99.413  1.00 19.84  ? 77  ASN S O     1 
ATOM   7458 C CB    . ASN E 4 77  ? 137.556 88.133  99.230  1.00 19.84  ? 77  ASN S CB    1 
ATOM   7459 C CG    . ASN E 4 77  ? 137.456 89.644  99.143  1.00 19.84  ? 77  ASN S CG    1 
ATOM   7460 O OD1   . ASN E 4 77  ? 136.459 90.187  98.671  1.00 19.84  ? 77  ASN S OD1   1 
ATOM   7461 N ND2   . ASN E 4 77  ? 138.497 90.331  99.600  1.00 19.84  ? 77  ASN S ND2   1 
ATOM   7462 N N     . THR E 4 78  ? 136.305 85.451  101.497 1.00 18.82  ? 78  THR S N     1 
ATOM   7463 C CA    . THR E 4 78  ? 136.316 84.000  101.634 1.00 18.82  ? 78  THR S CA    1 
ATOM   7464 C C     . THR E 4 78  ? 134.989 83.513  102.197 1.00 18.82  ? 78  THR S C     1 
ATOM   7465 O O     . THR E 4 78  ? 134.331 84.214  102.970 1.00 18.82  ? 78  THR S O     1 
ATOM   7466 C CB    . THR E 4 78  ? 137.468 83.536  102.534 1.00 18.82  ? 78  THR S CB    1 
ATOM   7467 O OG1   . THR E 4 78  ? 138.703 84.081  102.054 1.00 18.82  ? 78  THR S OG1   1 
ATOM   7468 C CG2   . THR E 4 78  ? 137.567 82.018  102.542 1.00 18.82  ? 78  THR S CG2   1 
ATOM   7469 N N     . LEU E 4 79  ? 134.605 82.304  101.796 1.00 16.38  ? 79  LEU S N     1 
ATOM   7470 C CA    . LEU E 4 79  ? 133.397 81.649  102.280 1.00 16.38  ? 79  LEU S CA    1 
ATOM   7471 C C     . LEU E 4 79  ? 133.770 80.280  102.830 1.00 16.38  ? 79  LEU S C     1 
ATOM   7472 O O     . LEU E 4 79  ? 134.617 79.591  102.257 1.00 16.38  ? 79  LEU S O     1 
ATOM   7473 C CB    . LEU E 4 79  ? 132.367 81.508  101.160 1.00 16.38  ? 79  LEU S CB    1 
ATOM   7474 C CG    . LEU E 4 79  ? 131.022 80.883  101.519 1.00 16.38  ? 79  LEU S CG    1 
ATOM   7475 C CD1   . LEU E 4 79  ? 130.262 81.728  102.524 1.00 16.38  ? 79  LEU S CD1   1 
ATOM   7476 C CD2   . LEU E 4 79  ? 130.206 80.649  100.263 1.00 16.38  ? 79  LEU S CD2   1 
ATOM   7477 N N     . PHE E 4 80  ? 133.151 79.890  103.941 1.00 19.38  ? 80  PHE S N     1 
ATOM   7478 C CA    . PHE E 4 80  ? 133.402 78.596  104.554 1.00 19.38  ? 80  PHE S CA    1 
ATOM   7479 C C     . PHE E 4 80  ? 132.098 77.831  104.736 1.00 19.38  ? 80  PHE S C     1 
ATOM   7480 O O     . PHE E 4 80  ? 131.053 78.413  105.039 1.00 19.38  ? 80  PHE S O     1 
ATOM   7481 C CB    . PHE E 4 80  ? 134.091 78.746  105.915 1.00 19.38  ? 80  PHE S CB    1 
ATOM   7482 C CG    . PHE E 4 80  ? 135.279 79.665  105.901 1.00 19.38  ? 80  PHE S CG    1 
ATOM   7483 C CD1   . PHE E 4 80  ? 136.513 79.214  105.467 1.00 19.38  ? 80  PHE S CD1   1 
ATOM   7484 C CD2   . PHE E 4 80  ? 135.165 80.973  106.336 1.00 19.38  ? 80  PHE S CD2   1 
ATOM   7485 C CE1   . PHE E 4 80  ? 137.608 80.054  105.460 1.00 19.38  ? 80  PHE S CE1   1 
ATOM   7486 C CE2   . PHE E 4 80  ? 136.257 81.817  106.331 1.00 19.38  ? 80  PHE S CE2   1 
ATOM   7487 C CZ    . PHE E 4 80  ? 137.480 81.356  105.892 1.00 19.38  ? 80  PHE S CZ    1 
ATOM   7488 N N     . LEU E 4 81  ? 132.180 76.514  104.558 1.00 20.79  ? 81  LEU S N     1 
ATOM   7489 C CA    . LEU E 4 81  ? 131.103 75.593  104.903 1.00 20.79  ? 81  LEU S CA    1 
ATOM   7490 C C     . LEU E 4 81  ? 131.713 74.501  105.767 1.00 20.79  ? 81  LEU S C     1 
ATOM   7491 O O     . LEU E 4 81  ? 132.405 73.616  105.257 1.00 20.79  ? 81  LEU S O     1 
ATOM   7492 C CB    . LEU E 4 81  ? 130.445 75.003  103.656 1.00 20.79  ? 81  LEU S CB    1 
ATOM   7493 C CG    . LEU E 4 81  ? 129.265 74.059  103.896 1.00 20.79  ? 81  LEU S CG    1 
ATOM   7494 C CD1   . LEU E 4 81  ? 128.045 74.840  104.351 1.00 20.79  ? 81  LEU S CD1   1 
ATOM   7495 C CD2   . LEU E 4 81  ? 128.952 73.262  102.642 1.00 20.79  ? 81  LEU S CD2   1 
ATOM   7496 N N     . GLN E 4 82  ? 131.473 74.576  107.073 1.00 26.77  ? 82  GLN S N     1 
ATOM   7497 C CA    . GLN E 4 82  ? 132.007 73.615  108.035 1.00 26.77  ? 82  GLN S CA    1 
ATOM   7498 C C     . GLN E 4 82  ? 130.949 72.534  108.222 1.00 26.77  ? 82  GLN S C     1 
ATOM   7499 O O     . GLN E 4 82  ? 129.841 72.795  108.692 1.00 26.77  ? 82  GLN S O     1 
ATOM   7500 C CB    . GLN E 4 82  ? 132.368 74.307  109.344 1.00 26.77  ? 82  GLN S CB    1 
ATOM   7501 C CG    . GLN E 4 82  ? 132.584 73.375  110.522 1.00 26.77  ? 82  GLN S CG    1 
ATOM   7502 C CD    . GLN E 4 82  ? 133.515 72.226  110.196 1.00 26.77  ? 82  GLN S CD    1 
ATOM   7503 O OE1   . GLN E 4 82  ? 134.671 72.433  109.833 1.00 26.77  ? 82  GLN S OE1   1 
ATOM   7504 N NE2   . GLN E 4 82  ? 133.016 71.004  110.331 1.00 26.77  ? 82  GLN S NE2   1 
ATOM   7505 N N     . MET E 4 83  ? 131.297 71.311  107.829 1.00 30.12  ? 83  MET S N     1 
ATOM   7506 C CA    . MET E 4 83  ? 130.397 70.173  107.936 1.00 30.12  ? 83  MET S CA    1 
ATOM   7507 C C     . MET E 4 83  ? 130.822 69.298  109.109 1.00 30.12  ? 83  MET S C     1 
ATOM   7508 O O     . MET E 4 83  ? 131.979 68.868  109.189 1.00 30.12  ? 83  MET S O     1 
ATOM   7509 C CB    . MET E 4 83  ? 130.414 69.375  106.635 1.00 30.12  ? 83  MET S CB    1 
ATOM   7510 C CG    . MET E 4 83  ? 129.871 70.148  105.441 1.00 30.12  ? 83  MET S CG    1 
ATOM   7511 S SD    . MET E 4 83  ? 129.872 69.196  103.913 1.00 30.12  ? 83  MET S SD    1 
ATOM   7512 C CE    . MET E 4 83  ? 131.620 69.197  103.529 1.00 30.12  ? 83  MET S CE    1 
ATOM   7513 N N     . THR E 4 84  ? 129.881 69.031  110.016 1.00 33.48  ? 84  THR S N     1 
ATOM   7514 C CA    . THR E 4 84  ? 130.171 68.383  111.291 1.00 33.48  ? 84  THR S CA    1 
ATOM   7515 C C     . THR E 4 84  ? 130.056 66.864  111.226 1.00 33.48  ? 84  THR S C     1 
ATOM   7516 O O     . THR E 4 84  ? 131.036 66.159  111.481 1.00 33.48  ? 84  THR S O     1 
ATOM   7517 C CB    . THR E 4 84  ? 129.226 68.921  112.372 1.00 33.48  ? 84  THR S CB    1 
ATOM   7518 O OG1   . THR E 4 84  ? 127.886 68.497  112.092 1.00 33.48  ? 84  THR S OG1   1 
ATOM   7519 C CG2   . THR E 4 84  ? 129.274 70.443  112.420 1.00 33.48  ? 84  THR S CG2   1 
ATOM   7520 N N     . SER E 4 85  ? 128.876 66.346  110.896 1.00 36.75  ? 85  SER S N     1 
ATOM   7521 C CA    . SER E 4 85  ? 128.645 64.913  110.772 1.00 36.75  ? 85  SER S CA    1 
ATOM   7522 C C     . SER E 4 85  ? 128.328 64.600  109.318 1.00 36.75  ? 85  SER S C     1 
ATOM   7523 O O     . SER E 4 85  ? 127.464 65.245  108.716 1.00 36.75  ? 85  SER S O     1 
ATOM   7524 C CB    . SER E 4 85  ? 127.503 64.454  111.682 1.00 36.75  ? 85  SER S CB    1 
ATOM   7525 O OG    . SER E 4 85  ? 127.832 64.645  113.046 1.00 36.75  ? 85  SER S OG    1 
ATOM   7526 N N     . LEU E 4 86  ? 129.029 63.618  108.757 1.00 36.49  ? 86  LEU S N     1 
ATOM   7527 C CA    . LEU E 4 86  ? 128.959 63.315  107.332 1.00 36.49  ? 86  LEU S CA    1 
ATOM   7528 C C     . LEU E 4 86  ? 128.493 61.876  107.153 1.00 36.49  ? 86  LEU S C     1 
ATOM   7529 O O     . LEU E 4 86  ? 129.247 60.936  107.425 1.00 36.49  ? 86  LEU S O     1 
ATOM   7530 C CB    . LEU E 4 86  ? 130.315 63.543  106.667 1.00 36.49  ? 86  LEU S CB    1 
ATOM   7531 C CG    . LEU E 4 86  ? 130.558 64.977  106.189 1.00 36.49  ? 86  LEU S CG    1 
ATOM   7532 C CD1   . LEU E 4 86  ? 130.595 65.936  107.366 1.00 36.49  ? 86  LEU S CD1   1 
ATOM   7533 C CD2   . LEU E 4 86  ? 131.846 65.066  105.395 1.00 36.49  ? 86  LEU S CD2   1 
ATOM   7534 N N     . ARG E 4 87  ? 127.257 61.709  106.694 1.00 39.29  ? 87  ARG S N     1 
ATOM   7535 C CA    . ARG E 4 87  ? 126.707 60.396  106.400 1.00 39.29  ? 87  ARG S CA    1 
ATOM   7536 C C     . ARG E 4 87  ? 127.148 59.971  105.001 1.00 39.29  ? 87  ARG S C     1 
ATOM   7537 O O     . ARG E 4 87  ? 127.842 60.706  104.294 1.00 39.29  ? 87  ARG S O     1 
ATOM   7538 C CB    . ARG E 4 87  ? 125.186 60.421  106.531 1.00 39.29  ? 87  ARG S CB    1 
ATOM   7539 C CG    . ARG E 4 87  ? 124.682 60.414  107.964 1.00 39.29  ? 87  ARG S CG    1 
ATOM   7540 C CD    . ARG E 4 87  ? 124.619 61.819  108.538 1.00 39.29  ? 87  ARG S CD    1 
ATOM   7541 N NE    . ARG E 4 87  ? 123.901 61.859  109.806 1.00 39.29  ? 87  ARG S NE    1 
ATOM   7542 C CZ    . ARG E 4 87  ? 124.460 61.685  110.997 1.00 39.29  ? 87  ARG S CZ    1 
ATOM   7543 N NH1   . ARG E 4 87  ? 125.754 61.439  111.126 1.00 39.29  ? 87  ARG S NH1   1 
ATOM   7544 N NH2   . ARG E 4 87  ? 123.701 61.755  112.086 1.00 39.29  ? 87  ARG S NH2   1 
ATOM   7545 N N     . SER E 4 88  ? 126.739 58.777  104.579 1.00 41.55  ? 88  SER S N     1 
ATOM   7546 C CA    . SER E 4 88  ? 127.051 58.298  103.239 1.00 41.55  ? 88  SER S CA    1 
ATOM   7547 C C     . SER E 4 88  ? 126.309 59.067  102.154 1.00 41.55  ? 88  SER S C     1 
ATOM   7548 O O     . SER E 4 88  ? 126.644 58.918  100.973 1.00 41.55  ? 88  SER S O     1 
ATOM   7549 C CB    . SER E 4 88  ? 126.727 56.807  103.124 1.00 41.55  ? 88  SER S CB    1 
ATOM   7550 O OG    . SER E 4 88  ? 125.346 56.567  103.332 1.00 41.55  ? 88  SER S OG    1 
ATOM   7551 N N     . GLU E 4 89  ? 125.320 59.878  102.520 1.00 38.39  ? 89  GLU S N     1 
ATOM   7552 C CA    . GLU E 4 89  ? 124.566 60.680  101.568 1.00 38.39  ? 89  GLU S CA    1 
ATOM   7553 C C     . GLU E 4 89  ? 125.200 62.044  101.329 1.00 38.39  ? 89  GLU S C     1 
ATOM   7554 O O     . GLU E 4 89  ? 124.764 62.768  100.430 1.00 38.39  ? 89  GLU S O     1 
ATOM   7555 C CB    . GLU E 4 89  ? 123.123 60.847  102.063 1.00 38.39  ? 89  GLU S CB    1 
ATOM   7556 C CG    . GLU E 4 89  ? 122.103 61.201  100.984 1.00 38.39  ? 89  GLU S CG    1 
ATOM   7557 C CD    . GLU E 4 89  ? 122.031 62.687  100.695 1.00 38.39  ? 89  GLU S CD    1 
ATOM   7558 O OE1   . GLU E 4 89  ? 121.714 63.461  101.623 1.00 38.39  ? 89  GLU S OE1   1 
ATOM   7559 O OE2   . GLU E 4 89  ? 122.289 63.082  99.538  1.00 38.39  ? 89  GLU S OE2   1 
ATOM   7560 N N     . ASP E 4 90  ? 126.233 62.400  102.093 1.00 34.54  ? 90  ASP S N     1 
ATOM   7561 C CA    . ASP E 4 90  ? 126.926 63.672  101.938 1.00 34.54  ? 90  ASP S CA    1 
ATOM   7562 C C     . ASP E 4 90  ? 128.063 63.594  100.925 1.00 34.54  ? 90  ASP S C     1 
ATOM   7563 O O     . ASP E 4 90  ? 128.942 64.461  100.922 1.00 34.54  ? 90  ASP S O     1 
ATOM   7564 C CB    . ASP E 4 90  ? 127.459 64.147  103.290 1.00 34.54  ? 90  ASP S CB    1 
ATOM   7565 C CG    . ASP E 4 90  ? 126.354 64.545  104.247 1.00 34.54  ? 90  ASP S CG    1 
ATOM   7566 O OD1   . ASP E 4 90  ? 125.588 65.474  103.919 1.00 34.54  ? 90  ASP S OD1   1 
ATOM   7567 O OD2   . ASP E 4 90  ? 126.250 63.928  105.328 1.00 34.54  ? 90  ASP S OD2   1 
ATOM   7568 N N     . THR E 4 91  ? 128.065 62.574  100.069 1.00 36.09  ? 91  THR S N     1 
ATOM   7569 C CA    . THR E 4 91  ? 129.080 62.427  99.029  1.00 36.09  ? 91  THR S CA    1 
ATOM   7570 C C     . THR E 4 91  ? 128.587 63.144  97.777  1.00 36.09  ? 91  THR S C     1 
ATOM   7571 O O     . THR E 4 91  ? 127.522 62.819  97.244  1.00 36.09  ? 91  THR S O     1 
ATOM   7572 C CB    . THR E 4 91  ? 129.366 60.953  98.749  1.00 36.09  ? 91  THR S CB    1 
ATOM   7573 O OG1   . THR E 4 91  ? 130.446 60.842  97.814  1.00 36.09  ? 91  THR S OG1   1 
ATOM   7574 C CG2   . THR E 4 91  ? 128.137 60.249  98.180  1.00 36.09  ? 91  THR S CG2   1 
ATOM   7575 N N     . ALA E 4 92  ? 129.355 64.126  97.314  1.00 29.62  ? 92  ALA S N     1 
ATOM   7576 C CA    . ALA E 4 92  ? 128.937 64.938  96.180  1.00 29.62  ? 92  ALA S CA    1 
ATOM   7577 C C     . ALA E 4 92  ? 130.035 65.936  95.854  1.00 29.62  ? 92  ALA S C     1 
ATOM   7578 O O     . ALA E 4 92  ? 131.012 66.078  96.593  1.00 29.62  ? 92  ALA S O     1 
ATOM   7579 C CB    . ALA E 4 92  ? 127.621 65.668  96.470  1.00 29.62  ? 92  ALA S CB    1 
ATOM   7580 N N     . MET E 4 93  ? 129.862 66.625  94.732  1.00 26.62  ? 93  MET S N     1 
ATOM   7581 C CA    . MET E 4 93  ? 130.726 67.737  94.366  1.00 26.62  ? 93  MET S CA    1 
ATOM   7582 C C     . MET E 4 93  ? 129.994 69.028  94.720  1.00 26.62  ? 93  MET S C     1 
ATOM   7583 O O     . MET E 4 93  ? 128.873 69.261  94.255  1.00 26.62  ? 93  MET S O     1 
ATOM   7584 C CB    . MET E 4 93  ? 131.094 67.662  92.882  1.00 26.62  ? 93  MET S CB    1 
ATOM   7585 C CG    . MET E 4 93  ? 131.614 68.946  92.244  1.00 26.62  ? 93  MET S CG    1 
ATOM   7586 S SD    . MET E 4 93  ? 131.376 68.931  90.458  1.00 26.62  ? 93  MET S SD    1 
ATOM   7587 C CE    . MET E 4 93  ? 132.615 67.737  89.961  1.00 26.62  ? 93  MET S CE    1 
ATOM   7588 N N     . TYR E 4 94  ? 130.619 69.842  95.565  1.00 23.80  ? 94  TYR S N     1 
ATOM   7589 C CA    . TYR E 4 94  ? 129.993 71.013  96.159  1.00 23.80  ? 94  TYR S CA    1 
ATOM   7590 C C     . TYR E 4 94  ? 130.434 72.267  95.417  1.00 23.80  ? 94  TYR S C     1 
ATOM   7591 O O     . TYR E 4 94  ? 131.623 72.439  95.126  1.00 23.80  ? 94  TYR S O     1 
ATOM   7592 C CB    . TYR E 4 94  ? 130.354 71.119  97.641  1.00 23.80  ? 94  TYR S CB    1 
ATOM   7593 C CG    . TYR E 4 94  ? 129.655 70.097  98.511  1.00 23.80  ? 94  TYR S CG    1 
ATOM   7594 C CD1   . TYR E 4 94  ? 128.398 70.351  99.041  1.00 23.80  ? 94  TYR S CD1   1 
ATOM   7595 C CD2   . TYR E 4 94  ? 130.253 68.877  98.801  1.00 23.80  ? 94  TYR S CD2   1 
ATOM   7596 C CE1   . TYR E 4 94  ? 127.755 69.421  99.833  1.00 23.80  ? 94  TYR S CE1   1 
ATOM   7597 C CE2   . TYR E 4 94  ? 129.617 67.940  99.594  1.00 23.80  ? 94  TYR S CE2   1 
ATOM   7598 C CZ    . TYR E 4 94  ? 128.367 68.218  100.106 1.00 23.80  ? 94  TYR S CZ    1 
ATOM   7599 O OH    . TYR E 4 94  ? 127.724 67.293  100.896 1.00 23.80  ? 94  TYR S OH    1 
ATOM   7600 N N     . TYR E 4 95  ? 129.472 73.138  95.127  1.00 20.86  ? 95  TYR S N     1 
ATOM   7601 C CA    . TYR E 4 95  ? 129.675 74.353  94.356  1.00 20.86  ? 95  TYR S CA    1 
ATOM   7602 C C     . TYR E 4 95  ? 129.481 75.582  95.231  1.00 20.86  ? 95  TYR S C     1 
ATOM   7603 O O     . TYR E 4 95  ? 128.591 75.620  96.090  1.00 20.86  ? 95  TYR S O     1 
ATOM   7604 C CB    . TYR E 4 95  ? 128.701 74.426  93.179  1.00 20.86  ? 95  TYR S CB    1 
ATOM   7605 C CG    . TYR E 4 95  ? 128.822 73.287  92.201  1.00 20.86  ? 95  TYR S CG    1 
ATOM   7606 C CD1   . TYR E 4 95  ? 130.045 72.966  91.628  1.00 20.86  ? 95  TYR S CD1   1 
ATOM   7607 C CD2   . TYR E 4 95  ? 127.711 72.532  91.845  1.00 20.86  ? 95  TYR S CD2   1 
ATOM   7608 C CE1   . TYR E 4 95  ? 130.158 71.929  90.730  1.00 20.86  ? 95  TYR S CE1   1 
ATOM   7609 C CE2   . TYR E 4 95  ? 127.815 71.492  90.949  1.00 20.86  ? 95  TYR S CE2   1 
ATOM   7610 C CZ    . TYR E 4 95  ? 129.040 71.194  90.395  1.00 20.86  ? 95  TYR S CZ    1 
ATOM   7611 O OH    . TYR E 4 95  ? 129.153 70.156  89.501  1.00 20.86  ? 95  TYR S OH    1 
ATOM   7612 N N     . CYS E 4 96  ? 130.314 76.586  94.982  1.00 17.04  ? 96  CYS S N     1 
ATOM   7613 C CA    . CYS E 4 96  ? 130.245 77.895  95.614  1.00 17.04  ? 96  CYS S CA    1 
ATOM   7614 C C     . CYS E 4 96  ? 129.691 78.878  94.591  1.00 17.04  ? 96  CYS S C     1 
ATOM   7615 O O     . CYS E 4 96  ? 130.229 78.988  93.485  1.00 17.04  ? 96  CYS S O     1 
ATOM   7616 C CB    . CYS E 4 96  ? 131.638 78.309  96.088  1.00 17.04  ? 96  CYS S CB    1 
ATOM   7617 S SG    . CYS E 4 96  ? 131.795 79.898  96.897  1.00 17.04  ? 96  CYS S SG    1 
ATOM   7618 N N     . VAL E 4 97  ? 128.619 79.584  94.951  1.00 12.77  ? 97  VAL S N     1 
ATOM   7619 C CA    . VAL E 4 97  ? 127.910 80.437  94.008  1.00 12.77  ? 97  VAL S CA    1 
ATOM   7620 C C     . VAL E 4 97  ? 127.700 81.810  94.631  1.00 12.77  ? 97  VAL S C     1 
ATOM   7621 O O     . VAL E 4 97  ? 127.461 81.944  95.831  1.00 12.77  ? 97  VAL S O     1 
ATOM   7622 C CB    . VAL E 4 97  ? 126.561 79.819  93.590  1.00 12.77  ? 97  VAL S CB    1 
ATOM   7623 C CG1   . VAL E 4 97  ? 125.913 80.644  92.499  1.00 12.77  ? 97  VAL S CG1   1 
ATOM   7624 C CG2   . VAL E 4 97  ? 126.758 78.381  93.140  1.00 12.77  ? 97  VAL S CG2   1 
ATOM   7625 N N     . ARG E 4 98  ? 127.791 82.840  93.792  1.00 11.44  ? 98  ARG S N     1 
ATOM   7626 C CA    . ARG E 4 98  ? 127.555 84.217  94.203  1.00 11.44  ? 98  ARG S CA    1 
ATOM   7627 C C     . ARG E 4 98  ? 126.162 84.647  93.764  1.00 11.44  ? 98  ARG S C     1 
ATOM   7628 O O     . ARG E 4 98  ? 125.645 84.182  92.745  1.00 11.44  ? 98  ARG S O     1 
ATOM   7629 C CB    . ARG E 4 98  ? 128.614 85.165  93.620  1.00 11.44  ? 98  ARG S CB    1 
ATOM   7630 C CG    . ARG E 4 98  ? 128.534 85.368  92.112  1.00 11.44  ? 98  ARG S CG    1 
ATOM   7631 C CD    . ARG E 4 98  ? 129.389 86.541  91.663  1.00 11.44  ? 98  ARG S CD    1 
ATOM   7632 N NE    . ARG E 4 98  ? 128.869 87.168  90.455  1.00 11.44  ? 98  ARG S NE    1 
ATOM   7633 C CZ    . ARG E 4 98  ? 129.443 88.189  89.833  1.00 11.44  ? 98  ARG S CZ    1 
ATOM   7634 N NH1   . ARG E 4 98  ? 130.563 88.732  90.282  1.00 11.44  ? 98  ARG S NH1   1 
ATOM   7635 N NH2   . ARG E 4 98  ? 128.880 88.678  88.732  1.00 11.44  ? 98  ARG S NH2   1 
ATOM   7636 N N     . SER E 4 99  ? 125.558 85.543  94.542  1.00 10.79  ? 99  SER S N     1 
ATOM   7637 C CA    . SER E 4 99  ? 124.176 85.943  94.317  1.00 10.79  ? 99  SER S CA    1 
ATOM   7638 C C     . SER E 4 99  ? 123.935 87.307  94.942  1.00 10.79  ? 99  SER S C     1 
ATOM   7639 O O     . SER E 4 99  ? 124.043 87.452  96.161  1.00 10.79  ? 99  SER S O     1 
ATOM   7640 C CB    . SER E 4 99  ? 123.216 84.915  94.921  1.00 10.79  ? 99  SER S CB    1 
ATOM   7641 O OG    . SER E 4 99  ? 121.886 85.157  94.503  1.00 10.79  ? 99  SER S OG    1 
ATOM   7642 N N     . ILE E 4 100 ? 123.582 88.289  94.118  1.00 8.58   ? 100 ILE S N     1 
ATOM   7643 C CA    . ILE E 4 100 ? 123.312 89.648  94.572  1.00 8.58   ? 100 ILE S CA    1 
ATOM   7644 C C     . ILE E 4 100 ? 121.853 89.959  94.279  1.00 8.58   ? 100 ILE S C     1 
ATOM   7645 O O     . ILE E 4 100 ? 121.349 89.631  93.199  1.00 8.58   ? 100 ILE S O     1 
ATOM   7646 C CB    . ILE E 4 100 ? 124.245 90.672  93.898  1.00 8.58   ? 100 ILE S CB    1 
ATOM   7647 C CG1   . ILE E 4 100 ? 124.260 91.983  94.685  1.00 8.58   ? 100 ILE S CG1   1 
ATOM   7648 C CG2   . ILE E 4 100 ? 123.827 90.922  92.458  1.00 8.58   ? 100 ILE S CG2   1 
ATOM   7649 C CD1   . ILE E 4 100 ? 125.451 92.858  94.379  1.00 8.58   ? 100 ILE S CD1   1 
ATOM   7650 N N     . TYR E 4 101 ? 121.176 90.581  95.242  1.00 8.65   ? 101 TYR S N     1 
ATOM   7651 C CA    . TYR E 4 101 ? 119.738 90.820  95.166  1.00 8.65   ? 101 TYR S CA    1 
ATOM   7652 C C     . TYR E 4 101 ? 119.461 92.316  95.223  1.00 8.65   ? 101 TYR S C     1 
ATOM   7653 O O     . TYR E 4 101 ? 119.639 92.951  96.267  1.00 8.65   ? 101 TYR S O     1 
ATOM   7654 C CB    . TYR E 4 101 ? 119.006 90.091  96.290  1.00 8.65   ? 101 TYR S CB    1 
ATOM   7655 C CG    . TYR E 4 101 ? 119.254 88.604  96.309  1.00 8.65   ? 101 TYR S CG    1 
ATOM   7656 C CD1   . TYR E 4 101 ? 118.485 87.746  95.539  1.00 8.65   ? 101 TYR S CD1   1 
ATOM   7657 C CD2   . TYR E 4 101 ? 120.257 88.058  97.096  1.00 8.65   ? 101 TYR S CD2   1 
ATOM   7658 C CE1   . TYR E 4 101 ? 118.706 86.390  95.551  1.00 8.65   ? 101 TYR S CE1   1 
ATOM   7659 C CE2   . TYR E 4 101 ? 120.485 86.700  97.115  1.00 8.65   ? 101 TYR S CE2   1 
ATOM   7660 C CZ    . TYR E 4 101 ? 119.706 85.870  96.341  1.00 8.65   ? 101 TYR S CZ    1 
ATOM   7661 O OH    . TYR E 4 101 ? 119.926 84.512  96.356  1.00 8.65   ? 101 TYR S OH    1 
ATOM   7662 N N     . TYR E 4 102 ? 119.032 92.868  94.094  1.00 6.05   ? 102 TYR S N     1 
ATOM   7663 C CA    . TYR E 4 102 ? 118.453 94.200  94.027  1.00 6.05   ? 102 TYR S CA    1 
ATOM   7664 C C     . TYR E 4 102 ? 117.630 94.247  92.752  1.00 6.05   ? 102 TYR S C     1 
ATOM   7665 O O     . TYR E 4 102 ? 117.741 93.370  91.893  1.00 6.05   ? 102 TYR S O     1 
ATOM   7666 C CB    . TYR E 4 102 ? 119.521 95.301  94.058  1.00 6.05   ? 102 TYR S CB    1 
ATOM   7667 C CG    . TYR E 4 102 ? 120.566 95.208  92.970  1.00 6.05   ? 102 TYR S CG    1 
ATOM   7668 C CD1   . TYR E 4 102 ? 120.308 95.678  91.689  1.00 6.05   ? 102 TYR S CD1   1 
ATOM   7669 C CD2   . TYR E 4 102 ? 121.815 94.662  93.226  1.00 6.05   ? 102 TYR S CD2   1 
ATOM   7670 C CE1   . TYR E 4 102 ? 121.259 95.599  90.696  1.00 6.05   ? 102 TYR S CE1   1 
ATOM   7671 C CE2   . TYR E 4 102 ? 122.772 94.579  92.239  1.00 6.05   ? 102 TYR S CE2   1 
ATOM   7672 C CZ    . TYR E 4 102 ? 122.490 95.049  90.976  1.00 6.05   ? 102 TYR S CZ    1 
ATOM   7673 O OH    . TYR E 4 102 ? 123.445 94.967  89.990  1.00 6.05   ? 102 TYR S OH    1 
ATOM   7674 N N     . TYR E 4 103 ? 116.788 95.270  92.640  1.00 6.18   ? 103 TYR S N     1 
ATOM   7675 C CA    . TYR E 4 103 ? 115.883 95.348  91.502  1.00 6.18   ? 103 TYR S CA    1 
ATOM   7676 C C     . TYR E 4 103 ? 116.653 95.188  90.197  1.00 6.18   ? 103 TYR S C     1 
ATOM   7677 O O     . TYR E 4 103 ? 117.518 96.009  89.874  1.00 6.18   ? 103 TYR S O     1 
ATOM   7678 C CB    . TYR E 4 103 ? 115.119 96.670  91.499  1.00 6.18   ? 103 TYR S CB    1 
ATOM   7679 C CG    . TYR E 4 103 ? 114.219 96.822  90.297  1.00 6.18   ? 103 TYR S CG    1 
ATOM   7680 C CD1   . TYR E 4 103 ? 113.013 96.142  90.220  1.00 6.18   ? 103 TYR S CD1   1 
ATOM   7681 C CD2   . TYR E 4 103 ? 114.584 97.629  89.231  1.00 6.18   ? 103 TYR S CD2   1 
ATOM   7682 C CE1   . TYR E 4 103 ? 112.191 96.270  89.120  1.00 6.18   ? 103 TYR S CE1   1 
ATOM   7683 C CE2   . TYR E 4 103 ? 113.768 97.764  88.128  1.00 6.18   ? 103 TYR S CE2   1 
ATOM   7684 C CZ    . TYR E 4 103 ? 112.573 97.082  88.077  1.00 6.18   ? 103 TYR S CZ    1 
ATOM   7685 O OH    . TYR E 4 103 ? 111.756 97.214  86.979  1.00 6.18   ? 103 TYR S OH    1 
ATOM   7686 N N     . GLY E 4 104 ? 116.353 94.127  89.449  1.00 7.25   ? 104 GLY S N     1 
ATOM   7687 C CA    . GLY E 4 104 ? 116.954 93.892  88.151  1.00 7.25   ? 104 GLY S CA    1 
ATOM   7688 C C     . GLY E 4 104 ? 118.220 93.062  88.163  1.00 7.25   ? 104 GLY S C     1 
ATOM   7689 O O     . GLY E 4 104 ? 118.751 92.771  87.085  1.00 7.25   ? 104 GLY S O     1 
ATOM   7690 N N     . SER E 4 105 ? 118.720 92.664  89.329  1.00 7.73   ? 105 SER S N     1 
ATOM   7691 C CA    . SER E 4 105 ? 119.979 91.940  89.396  1.00 7.73   ? 105 SER S CA    1 
ATOM   7692 C C     . SER E 4 105 ? 119.801 90.483  88.976  1.00 7.73   ? 105 SER S C     1 
ATOM   7693 O O     . SER E 4 105 ? 118.694 89.938  88.961  1.00 7.73   ? 105 SER S O     1 
ATOM   7694 C CB    . SER E 4 105 ? 120.561 91.995  90.808  1.00 7.73   ? 105 SER S CB    1 
ATOM   7695 O OG    . SER E 4 105 ? 119.750 91.287  91.726  1.00 7.73   ? 105 SER S OG    1 
ATOM   7696 N N     . SER E 4 106 ? 120.924 89.854  88.627  1.00 11.98  ? 106 SER S N     1 
ATOM   7697 C CA    . SER E 4 106 ? 120.963 88.432  88.328  1.00 11.98  ? 106 SER S CA    1 
ATOM   7698 C C     . SER E 4 106 ? 121.547 87.703  89.529  1.00 11.98  ? 106 SER S C     1 
ATOM   7699 O O     . SER E 4 106 ? 122.747 87.854  89.804  1.00 11.98  ? 106 SER S O     1 
ATOM   7700 C CB    . SER E 4 106 ? 121.805 88.168  87.084  1.00 11.98  ? 106 SER S CB    1 
ATOM   7701 O OG    . SER E 4 106 ? 123.187 88.206  87.391  1.00 11.98  ? 106 SER S OG    1 
ATOM   7702 N N     . PRO E 4 107 ? 120.769 86.914  90.267  1.00 12.99  ? 107 PRO S N     1 
ATOM   7703 C CA    . PRO E 4 107 ? 121.258 86.350  91.534  1.00 12.99  ? 107 PRO S CA    1 
ATOM   7704 C C     . PRO E 4 107 ? 122.002 85.024  91.432  1.00 12.99  ? 107 PRO S C     1 
ATOM   7705 O O     . PRO E 4 107 ? 122.313 84.447  92.475  1.00 12.99  ? 107 PRO S O     1 
ATOM   7706 C CB    . PRO E 4 107 ? 119.959 86.169  92.329  1.00 12.99  ? 107 PRO S CB    1 
ATOM   7707 C CG    . PRO E 4 107 ? 118.922 85.907  91.306  1.00 12.99  ? 107 PRO S CG    1 
ATOM   7708 C CD    . PRO E 4 107 ? 119.343 86.611  90.048  1.00 12.99  ? 107 PRO S CD    1 
ATOM   7709 N N     . PHE E 4 108 ? 122.269 84.495  90.242  1.00 14.70  ? 108 PHE S N     1 
ATOM   7710 C CA    . PHE E 4 108 ? 123.126 83.319  90.109  1.00 14.70  ? 108 PHE S CA    1 
ATOM   7711 C C     . PHE E 4 108 ? 124.008 83.430  88.874  1.00 14.70  ? 108 PHE S C     1 
ATOM   7712 O O     . PHE E 4 108 ? 124.155 82.475  88.106  1.00 14.70  ? 108 PHE S O     1 
ATOM   7713 C CB    . PHE E 4 108 ? 122.301 82.034  90.086  1.00 14.70  ? 108 PHE S CB    1 
ATOM   7714 C CG    . PHE E 4 108 ? 121.808 81.612  91.441  1.00 14.70  ? 108 PHE S CG    1 
ATOM   7715 C CD1   . PHE E 4 108 ? 122.605 80.838  92.266  1.00 14.70  ? 108 PHE S CD1   1 
ATOM   7716 C CD2   . PHE E 4 108 ? 120.557 81.983  91.890  1.00 14.70  ? 108 PHE S CD2   1 
ATOM   7717 C CE1   . PHE E 4 108 ? 122.163 80.444  93.513  1.00 14.70  ? 108 PHE S CE1   1 
ATOM   7718 C CE2   . PHE E 4 108 ? 120.112 81.594  93.139  1.00 14.70  ? 108 PHE S CE2   1 
ATOM   7719 C CZ    . PHE E 4 108 ? 120.914 80.822  93.948  1.00 14.70  ? 108 PHE S CZ    1 
ATOM   7720 N N     . ASP E 4 109 ? 124.610 84.603  88.667  1.00 14.07  ? 109 ASP S N     1 
ATOM   7721 C CA    . ASP E 4 109 ? 125.381 84.834  87.450  1.00 14.07  ? 109 ASP S CA    1 
ATOM   7722 C C     . ASP E 4 109 ? 126.558 83.873  87.335  1.00 14.07  ? 109 ASP S C     1 
ATOM   7723 O O     . ASP E 4 109 ? 126.815 83.329  86.255  1.00 14.07  ? 109 ASP S O     1 
ATOM   7724 C CB    . ASP E 4 109 ? 125.875 86.280  87.413  1.00 14.07  ? 109 ASP S CB    1 
ATOM   7725 C CG    . ASP E 4 109 ? 125.784 86.895  86.026  1.00 14.07  ? 109 ASP S CG    1 
ATOM   7726 O OD1   . ASP E 4 109 ? 125.950 86.156  85.031  1.00 14.07  ? 109 ASP S OD1   1 
ATOM   7727 O OD2   . ASP E 4 109 ? 125.550 88.119  85.931  1.00 14.07  ? 109 ASP S OD2   1 
ATOM   7728 N N     . PHE E 4 110 ? 127.282 83.646  88.427  1.00 12.28  ? 110 PHE S N     1 
ATOM   7729 C CA    . PHE E 4 110 ? 128.556 82.942  88.385  1.00 12.28  ? 110 PHE S CA    1 
ATOM   7730 C C     . PHE E 4 110 ? 128.554 81.772  89.358  1.00 12.28  ? 110 PHE S C     1 
ATOM   7731 O O     . PHE E 4 110 ? 128.231 81.939  90.537  1.00 12.28  ? 110 PHE S O     1 
ATOM   7732 C CB    . PHE E 4 110 ? 129.708 83.897  88.714  1.00 12.28  ? 110 PHE S CB    1 
ATOM   7733 C CG    . PHE E 4 110 ? 131.058 83.384  88.305  1.00 12.28  ? 110 PHE S CG    1 
ATOM   7734 C CD1   . PHE E 4 110 ? 131.363 83.182  86.971  1.00 12.28  ? 110 PHE S CD1   1 
ATOM   7735 C CD2   . PHE E 4 110 ? 132.023 83.109  89.257  1.00 12.28  ? 110 PHE S CD2   1 
ATOM   7736 C CE1   . PHE E 4 110 ? 132.604 82.711  86.597  1.00 12.28  ? 110 PHE S CE1   1 
ATOM   7737 C CE2   . PHE E 4 110 ? 133.266 82.638  88.887  1.00 12.28  ? 110 PHE S CE2   1 
ATOM   7738 C CZ    . PHE E 4 110 ? 133.556 82.439  87.557  1.00 12.28  ? 110 PHE S CZ    1 
ATOM   7739 N N     . TRP E 4 111 ? 128.924 80.596  88.857  1.00 14.86  ? 111 TRP S N     1 
ATOM   7740 C CA    . TRP E 4 111 ? 129.172 79.415  89.669  1.00 14.86  ? 111 TRP S CA    1 
ATOM   7741 C C     . TRP E 4 111 ? 130.667 79.135  89.721  1.00 14.86  ? 111 TRP S C     1 
ATOM   7742 O O     . TRP E 4 111 ? 131.415 79.499  88.810  1.00 14.86  ? 111 TRP S O     1 
ATOM   7743 C CB    . TRP E 4 111 ? 128.457 78.184  89.106  1.00 14.86  ? 111 TRP S CB    1 
ATOM   7744 C CG    . TRP E 4 111 ? 126.967 78.220  89.191  1.00 14.86  ? 111 TRP S CG    1 
ATOM   7745 C CD1   . TRP E 4 111 ? 126.136 79.170  88.678  1.00 14.86  ? 111 TRP S CD1   1 
ATOM   7746 C CD2   . TRP E 4 111 ? 126.127 77.246  89.817  1.00 14.86  ? 111 TRP S CD2   1 
ATOM   7747 N NE1   . TRP E 4 111 ? 124.828 78.851  88.950  1.00 14.86  ? 111 TRP S NE1   1 
ATOM   7748 C CE2   . TRP E 4 111 ? 124.796 77.673  89.649  1.00 14.86  ? 111 TRP S CE2   1 
ATOM   7749 C CE3   . TRP E 4 111 ? 126.371 76.054  90.506  1.00 14.86  ? 111 TRP S CE3   1 
ATOM   7750 C CZ2   . TRP E 4 111 ? 123.714 76.951  90.147  1.00 14.86  ? 111 TRP S CZ2   1 
ATOM   7751 C CZ3   . TRP E 4 111 ? 125.296 75.341  90.997  1.00 14.86  ? 111 TRP S CZ3   1 
ATOM   7752 C CH2   . TRP E 4 111 ? 123.985 75.791  90.815  1.00 14.86  ? 111 TRP S CH2   1 
ATOM   7753 N N     . GLY E 4 112 ? 131.099 78.478  90.795  1.00 16.22  ? 112 GLY S N     1 
ATOM   7754 C CA    . GLY E 4 112 ? 132.468 78.031  90.925  1.00 16.22  ? 112 GLY S CA    1 
ATOM   7755 C C     . GLY E 4 112 ? 132.709 76.731  90.181  1.00 16.22  ? 112 GLY S C     1 
ATOM   7756 O O     . GLY E 4 112 ? 131.822 76.172  89.534  1.00 16.22  ? 112 GLY S O     1 
ATOM   7757 N N     . GLN E 4 113 ? 133.949 76.244  90.279  1.00 21.25  ? 113 GLN S N     1 
ATOM   7758 C CA    . GLN E 4 113 ? 134.319 74.999  89.615  1.00 21.25  ? 113 GLN S CA    1 
ATOM   7759 C C     . GLN E 4 113 ? 134.018 73.767  90.460  1.00 21.25  ? 113 GLN S C     1 
ATOM   7760 O O     . GLN E 4 113 ? 134.053 72.649  89.933  1.00 21.25  ? 113 GLN S O     1 
ATOM   7761 C CB    . GLN E 4 113 ? 135.809 75.018  89.257  1.00 21.25  ? 113 GLN S CB    1 
ATOM   7762 C CG    . GLN E 4 113 ? 136.212 76.040  88.191  1.00 21.25  ? 113 GLN S CG    1 
ATOM   7763 C CD    . GLN E 4 113 ? 135.173 76.227  87.096  1.00 21.25  ? 113 GLN S CD    1 
ATOM   7764 O OE1   . GLN E 4 113 ? 134.561 75.265  86.631  1.00 21.25  ? 113 GLN S OE1   1 
ATOM   7765 N NE2   . GLN E 4 113 ? 134.968 77.472  86.682  1.00 21.25  ? 113 GLN S NE2   1 
ATOM   7766 N N     . GLY E 4 114 ? 133.730 73.941  91.746  1.00 23.37  ? 114 GLY S N     1 
ATOM   7767 C CA    . GLY E 4 114 ? 133.333 72.848  92.606  1.00 23.37  ? 114 GLY S CA    1 
ATOM   7768 C C     . GLY E 4 114 ? 134.510 72.119  93.232  1.00 23.37  ? 114 GLY S C     1 
ATOM   7769 O O     . GLY E 4 114 ? 135.665 72.246  92.820  1.00 23.37  ? 114 GLY S O     1 
ATOM   7770 N N     . THR E 4 115 ? 134.196 71.334  94.264  1.00 26.01  ? 115 THR S N     1 
ATOM   7771 C CA    . THR E 4 115 ? 135.178 70.494  94.937  1.00 26.01  ? 115 THR S CA    1 
ATOM   7772 C C     . THR E 4 115 ? 134.505 69.203  95.378  1.00 26.01  ? 115 THR S C     1 
ATOM   7773 O O     . THR E 4 115 ? 133.375 69.226  95.866  1.00 26.01  ? 115 THR S O     1 
ATOM   7774 C CB    . THR E 4 115 ? 135.798 71.205  96.149  1.00 26.01  ? 115 THR S CB    1 
ATOM   7775 O OG1   . THR E 4 115 ? 136.824 70.383  96.717  1.00 26.01  ? 115 THR S OG1   1 
ATOM   7776 C CG2   . THR E 4 115 ? 134.743 71.497  97.206  1.00 26.01  ? 115 THR S CG2   1 
ATOM   7777 N N     . THR E 4 116 ? 135.202 68.082  95.218  1.00 29.82  ? 116 THR S N     1 
ATOM   7778 C CA    . THR E 4 116 ? 134.605 66.769  95.437  1.00 29.82  ? 116 THR S CA    1 
ATOM   7779 C C     . THR E 4 116 ? 134.792 66.311  96.877  1.00 29.82  ? 116 THR S C     1 
ATOM   7780 O O     . THR E 4 116 ? 135.856 66.505  97.471  1.00 29.82  ? 116 THR S O     1 
ATOM   7781 C CB    . THR E 4 116 ? 135.216 65.735  94.489  1.00 29.82  ? 116 THR S CB    1 
ATOM   7782 O OG1   . THR E 4 116 ? 134.531 64.485  94.637  1.00 29.82  ? 116 THR S OG1   1 
ATOM   7783 C CG2   . THR E 4 116 ? 136.699 65.532  94.784  1.00 29.82  ? 116 THR S CG2   1 
ATOM   7784 N N     . LEU E 4 117 ? 133.751 65.689  97.432  1.00 33.44  ? 117 LEU S N     1 
ATOM   7785 C CA    . LEU E 4 117 ? 133.807 65.065  98.748  1.00 33.44  ? 117 LEU S CA    1 
ATOM   7786 C C     . LEU E 4 117 ? 133.205 63.673  98.645  1.00 33.44  ? 117 LEU S C     1 
ATOM   7787 O O     . LEU E 4 117 ? 132.079 63.516  98.160  1.00 33.44  ? 117 LEU S O     1 
ATOM   7788 C CB    . LEU E 4 117 ? 133.055 65.893  99.792  1.00 33.44  ? 117 LEU S CB    1 
ATOM   7789 C CG    . LEU E 4 117 ? 133.420 65.604  101.250 1.00 33.44  ? 117 LEU S CG    1 
ATOM   7790 C CD1   . LEU E 4 117 ? 134.814 66.114  101.575 1.00 33.44  ? 117 LEU S CD1   1 
ATOM   7791 C CD2   . LEU E 4 117 ? 132.392 66.213  102.183 1.00 33.44  ? 117 LEU S CD2   1 
ATOM   7792 N N     . THR E 4 118 ? 133.950 62.674  99.105  1.00 39.40  ? 118 THR S N     1 
ATOM   7793 C CA    . THR E 4 118 ? 133.514 61.287  99.104  1.00 39.40  ? 118 THR S CA    1 
ATOM   7794 C C     . THR E 4 118 ? 133.373 60.797  100.538 1.00 39.40  ? 118 THR S C     1 
ATOM   7795 O O     . THR E 4 118 ? 134.192 61.129  101.401 1.00 39.40  ? 118 THR S O     1 
ATOM   7796 C CB    . THR E 4 118 ? 134.505 60.398  98.348  1.00 39.40  ? 118 THR S CB    1 
ATOM   7797 O OG1   . THR E 4 118 ? 134.904 61.045  97.133  1.00 39.40  ? 118 THR S OG1   1 
ATOM   7798 C CG2   . THR E 4 118 ? 133.875 59.053  98.020  1.00 39.40  ? 118 THR S CG2   1 
ATOM   7799 N N     . VAL E 4 119 ? 132.318 60.025  100.789 1.00 40.53  ? 119 VAL S N     1 
ATOM   7800 C CA    . VAL E 4 119 ? 132.050 59.442  102.097 1.00 40.53  ? 119 VAL S CA    1 
ATOM   7801 C C     . VAL E 4 119 ? 131.873 57.942  101.919 1.00 40.53  ? 119 VAL S C     1 
ATOM   7802 O O     . VAL E 4 119 ? 131.148 57.501  101.020 1.00 40.53  ? 119 VAL S O     1 
ATOM   7803 C CB    . VAL E 4 119 ? 130.803 60.062  102.755 1.00 40.53  ? 119 VAL S CB    1 
ATOM   7804 C CG1   . VAL E 4 119 ? 130.752 59.698  104.234 1.00 40.53  ? 119 VAL S CG1   1 
ATOM   7805 C CG2   . VAL E 4 119 ? 130.790 61.571  102.562 1.00 40.53  ? 119 VAL S CG2   1 
ATOM   7806 N N     . SER E 4 120 ? 132.533 57.164  102.771 1.00 47.20  ? 120 SER S N     1 
ATOM   7807 C CA    . SER E 4 120 ? 132.432 55.715  102.688 1.00 47.20  ? 120 SER S CA    1 
ATOM   7808 C C     . SER E 4 120 ? 131.021 55.255  103.040 1.00 47.20  ? 120 SER S C     1 
ATOM   7809 O O     . SER E 4 120 ? 130.193 56.028  103.529 1.00 47.20  ? 120 SER S O     1 
ATOM   7810 C CB    . SER E 4 120 ? 133.445 55.055  103.622 1.00 47.20  ? 120 SER S CB    1 
ATOM   7811 O OG    . SER E 4 120 ? 133.319 53.644  103.594 1.00 47.20  ? 120 SER S OG    1 
ATOM   7812 N N     . SER E 4 121 ? 130.753 53.980  102.778 1.00 51.99  ? 121 SER S N     1 
ATOM   7813 C CA    . SER E 4 121 ? 129.448 53.397  103.062 1.00 51.99  ? 121 SER S CA    1 
ATOM   7814 C C     . SER E 4 121 ? 129.406 52.832  104.478 1.00 51.99  ? 121 SER S C     1 
ATOM   7815 O O     . SER E 4 121 ? 129.548 53.568  105.455 1.00 51.99  ? 121 SER S O     1 
ATOM   7816 C CB    . SER E 4 121 ? 129.119 52.301  102.047 1.00 51.99  ? 121 SER S CB    1 
ATOM   7817 O OG    . SER E 4 121 ? 128.923 52.846  100.755 1.00 51.99  ? 121 SER S OG    1 
ATOM   7818 N N     . SER E 4 136 ? 105.343 70.717  101.828 1.00 30.96  ? 124 SER S N     1 
ATOM   7819 C CA    . SER E 4 136 ? 106.128 71.834  102.341 1.00 30.96  ? 124 SER S CA    1 
ATOM   7820 C C     . SER E 4 136 ? 107.063 72.373  101.265 1.00 30.96  ? 124 SER S C     1 
ATOM   7821 O O     . SER E 4 136 ? 106.738 73.337  100.572 1.00 30.96  ? 124 SER S O     1 
ATOM   7822 C CB    . SER E 4 136 ? 106.930 71.404  103.571 1.00 30.96  ? 124 SER S CB    1 
ATOM   7823 O OG    . SER E 4 136 ? 107.735 70.273  103.283 1.00 30.96  ? 124 SER S OG    1 
ATOM   7824 N N     . ASP E 4 137 ? 108.228 71.742  101.130 1.00 27.52  ? 125 ASP S N     1 
ATOM   7825 C CA    . ASP E 4 137 ? 109.192 72.160  100.122 1.00 27.52  ? 125 ASP S CA    1 
ATOM   7826 C C     . ASP E 4 137 ? 108.610 71.972  98.728  1.00 27.52  ? 125 ASP S C     1 
ATOM   7827 O O     . ASP E 4 137 ? 107.962 70.961  98.443  1.00 27.52  ? 125 ASP S O     1 
ATOM   7828 C CB    . ASP E 4 137 ? 110.485 71.361  100.268 1.00 27.52  ? 125 ASP S CB    1 
ATOM   7829 C CG    . ASP E 4 137 ? 111.141 71.560  101.617 1.00 27.52  ? 125 ASP S CG    1 
ATOM   7830 O OD1   . ASP E 4 137 ? 110.532 72.220  102.484 1.00 27.52  ? 125 ASP S OD1   1 
ATOM   7831 O OD2   . ASP E 4 137 ? 112.266 71.055  101.811 1.00 27.52  ? 125 ASP S OD2   1 
ATOM   7832 N N     . ILE E 4 138 ? 108.843 72.953  97.857  1.00 22.67  ? 126 ILE S N     1 
ATOM   7833 C CA    . ILE E 4 138 ? 108.333 72.878  96.495  1.00 22.67  ? 126 ILE S CA    1 
ATOM   7834 C C     . ILE E 4 138 ? 109.072 71.779  95.746  1.00 22.67  ? 126 ILE S C     1 
ATOM   7835 O O     . ILE E 4 138 ? 110.304 71.680  95.808  1.00 22.67  ? 126 ILE S O     1 
ATOM   7836 C CB    . ILE E 4 138 ? 108.478 74.233  95.788  1.00 22.67  ? 126 ILE S CB    1 
ATOM   7837 C CG1   . ILE E 4 138 ? 107.777 75.325  96.599  1.00 22.67  ? 126 ILE S CG1   1 
ATOM   7838 C CG2   . ILE E 4 138 ? 107.906 74.165  94.376  1.00 22.67  ? 126 ILE S CG2   1 
ATOM   7839 C CD1   . ILE E 4 138 ? 107.857 76.702  95.982  1.00 22.67  ? 126 ILE S CD1   1 
ATOM   7840 N N     . VAL E 4 139 ? 108.319 70.944  95.038  1.00 23.69  ? 127 VAL S N     1 
ATOM   7841 C CA    . VAL E 4 139 ? 108.872 69.855  94.243  1.00 23.69  ? 127 VAL S CA    1 
ATOM   7842 C C     . VAL E 4 139 ? 108.746 70.226  92.775  1.00 23.69  ? 127 VAL S C     1 
ATOM   7843 O O     . VAL E 4 139 ? 107.670 70.632  92.317  1.00 23.69  ? 127 VAL S O     1 
ATOM   7844 C CB    . VAL E 4 139 ? 108.155 68.527  94.539  1.00 23.69  ? 127 VAL S CB    1 
ATOM   7845 C CG1   . VAL E 4 139 ? 108.598 67.452  93.558  1.00 23.69  ? 127 VAL S CG1   1 
ATOM   7846 C CG2   . VAL E 4 139 ? 108.416 68.091  95.971  1.00 23.69  ? 127 VAL S CG2   1 
ATOM   7847 N N     . MET E 4 140 ? 109.845 70.100  92.038  1.00 24.43  ? 128 MET S N     1 
ATOM   7848 C CA    . MET E 4 140 ? 109.876 70.381  90.611  1.00 24.43  ? 128 MET S CA    1 
ATOM   7849 C C     . MET E 4 140 ? 110.353 69.141  89.872  1.00 24.43  ? 128 MET S C     1 
ATOM   7850 O O     . MET E 4 140 ? 111.337 68.512  90.274  1.00 24.43  ? 128 MET S O     1 
ATOM   7851 C CB    . MET E 4 140 ? 110.784 71.568  90.300  1.00 24.43  ? 128 MET S CB    1 
ATOM   7852 C CG    . MET E 4 140 ? 110.129 72.914  90.552  1.00 24.43  ? 128 MET S CG    1 
ATOM   7853 S SD    . MET E 4 140 ? 111.291 74.112  91.213  1.00 24.43  ? 128 MET S SD    1 
ATOM   7854 C CE    . MET E 4 140 ? 112.679 73.826  90.126  1.00 24.43  ? 128 MET S CE    1 
ATOM   7855 N N     . THR E 4 141 ? 109.655 68.801  88.796  1.00 29.64  ? 129 THR S N     1 
ATOM   7856 C CA    . THR E 4 141 ? 109.913 67.585  88.040  1.00 29.64  ? 129 THR S CA    1 
ATOM   7857 C C     . THR E 4 141 ? 110.304 67.931  86.611  1.00 29.64  ? 129 THR S C     1 
ATOM   7858 O O     . THR E 4 141 ? 109.688 68.795  85.979  1.00 29.64  ? 129 THR S O     1 
ATOM   7859 C CB    . THR E 4 141 ? 108.684 66.667  88.029  1.00 29.64  ? 129 THR S CB    1 
ATOM   7860 O OG1   . THR E 4 141 ? 107.763 67.107  87.024  1.00 29.64  ? 129 THR S OG1   1 
ATOM   7861 C CG2   . THR E 4 141 ? 107.993 66.680  89.385  1.00 29.64  ? 129 THR S CG2   1 
ATOM   7862 N N     . GLN E 4 142 ? 111.326 67.248  86.106  1.00 32.38  ? 130 GLN S N     1 
ATOM   7863 C CA    . GLN E 4 142 ? 111.741 67.365  84.715  1.00 32.38  ? 130 GLN S CA    1 
ATOM   7864 C C     . GLN E 4 142 ? 111.147 66.198  83.937  1.00 32.38  ? 130 GLN S C     1 
ATOM   7865 O O     . GLN E 4 142 ? 111.405 65.034  84.262  1.00 32.38  ? 130 GLN S O     1 
ATOM   7866 C CB    . GLN E 4 142 ? 113.263 67.385  84.597  1.00 32.38  ? 130 GLN S CB    1 
ATOM   7867 C CG    . GLN E 4 142 ? 113.897 68.642  85.175  1.00 32.38  ? 130 GLN S CG    1 
ATOM   7868 C CD    . GLN E 4 142 ? 115.249 68.949  84.568  1.00 32.38  ? 130 GLN S CD    1 
ATOM   7869 O OE1   . GLN E 4 142 ? 115.739 68.214  83.714  1.00 32.38  ? 130 GLN S OE1   1 
ATOM   7870 N NE2   . GLN E 4 142 ? 115.857 70.043  85.004  1.00 32.38  ? 130 GLN S NE2   1 
ATOM   7871 N N     . ALA E 4 143 ? 110.353 66.515  82.911  1.00 39.68  ? 131 ALA S N     1 
ATOM   7872 C CA    . ALA E 4 143 ? 109.567 65.493  82.230  1.00 39.68  ? 131 ALA S CA    1 
ATOM   7873 C C     . ALA E 4 143 ? 110.434 64.374  81.670  1.00 39.68  ? 131 ALA S C     1 
ATOM   7874 O O     . ALA E 4 143 ? 109.997 63.219  81.619  1.00 39.68  ? 131 ALA S O     1 
ATOM   7875 C CB    . ALA E 4 143 ? 108.748 66.129  81.106  1.00 39.68  ? 131 ALA S CB    1 
ATOM   7876 N N     . THR E 4 144 ? 111.654 64.688  81.243  1.00 40.27  ? 132 THR S N     1 
ATOM   7877 C CA    . THR E 4 144 ? 112.538 63.714  80.620  1.00 40.27  ? 132 THR S CA    1 
ATOM   7878 C C     . THR E 4 144 ? 113.933 63.835  81.220  1.00 40.27  ? 132 THR S C     1 
ATOM   7879 O O     . THR E 4 144 ? 114.205 64.703  82.055  1.00 40.27  ? 132 THR S O     1 
ATOM   7880 C CB    . THR E 4 144 ? 112.588 63.904  79.099  1.00 40.27  ? 132 THR S CB    1 
ATOM   7881 O OG1   . THR E 4 144 ? 113.110 65.203  78.793  1.00 40.27  ? 132 THR S OG1   1 
ATOM   7882 C CG2   . THR E 4 144 ? 111.198 63.761  78.495  1.00 40.27  ? 132 THR S CG2   1 
ATOM   7883 N N     . SER E 4 145 ? 114.821 62.939  80.788  1.00 40.89  ? 133 SER S N     1 
ATOM   7884 C CA    . SER E 4 145 ? 116.213 62.962  81.216  1.00 40.89  ? 133 SER S CA    1 
ATOM   7885 C C     . SER E 4 145 ? 117.205 62.801  80.075  1.00 40.89  ? 133 SER S C     1 
ATOM   7886 O O     . SER E 4 145 ? 118.409 62.930  80.317  1.00 40.89  ? 133 SER S O     1 
ATOM   7887 C CB    . SER E 4 145 ? 116.470 61.860  82.254  1.00 40.89  ? 133 SER S CB    1 
ATOM   7888 O OG    . SER E 4 145 ? 117.828 61.850  82.661  1.00 40.89  ? 133 SER S OG    1 
ATOM   7889 N N     . SER E 4 146 ? 116.757 62.523  78.853  1.00 42.94  ? 134 SER S N     1 
ATOM   7890 C CA    . SER E 4 146 ? 117.650 62.389  77.712  1.00 42.94  ? 134 SER S CA    1 
ATOM   7891 C C     . SER E 4 146 ? 116.843 62.611  76.442  1.00 42.94  ? 134 SER S C     1 
ATOM   7892 O O     . SER E 4 146 ? 115.748 62.062  76.296  1.00 42.94  ? 134 SER S O     1 
ATOM   7893 C CB    . SER E 4 146 ? 118.323 61.012  77.687  1.00 42.94  ? 134 SER S CB    1 
ATOM   7894 O OG    . SER E 4 146 ? 119.219 60.901  76.594  1.00 42.94  ? 134 SER S OG    1 
ATOM   7895 N N     . VAL E 4 147 ? 117.387 63.415  75.533  1.00 44.45  ? 135 VAL S N     1 
ATOM   7896 C CA    . VAL E 4 147 ? 116.693 63.760  74.293  1.00 44.45  ? 135 VAL S CA    1 
ATOM   7897 C C     . VAL E 4 147 ? 117.702 63.819  73.151  1.00 44.45  ? 135 VAL S C     1 
ATOM   7898 O O     . VAL E 4 147 ? 118.544 64.728  73.123  1.00 44.45  ? 135 VAL S O     1 
ATOM   7899 C CB    . VAL E 4 147 ? 115.942 65.093  74.434  1.00 44.45  ? 135 VAL S CB    1 
ATOM   7900 C CG1   . VAL E 4 147 ? 115.603 65.668  73.065  1.00 44.45  ? 135 VAL S CG1   1 
ATOM   7901 C CG2   . VAL E 4 147 ? 114.681 64.906  75.265  1.00 44.45  ? 135 VAL S CG2   1 
ATOM   7902 N N     . PRO E 4 148 ? 117.668 62.888  72.197  1.00 47.44  ? 136 PRO S N     1 
ATOM   7903 C CA    . PRO E 4 148 ? 118.571 62.994  71.044  1.00 47.44  ? 136 PRO S CA    1 
ATOM   7904 C C     . PRO E 4 148 ? 118.236 64.205  70.188  1.00 47.44  ? 136 PRO S C     1 
ATOM   7905 O O     . PRO E 4 148 ? 117.074 64.601  70.065  1.00 47.44  ? 136 PRO S O     1 
ATOM   7906 C CB    . PRO E 4 148 ? 118.337 61.685  70.277  1.00 47.44  ? 136 PRO S CB    1 
ATOM   7907 C CG    . PRO E 4 148 ? 117.607 60.784  71.219  1.00 47.44  ? 136 PRO S CG    1 
ATOM   7908 C CD    . PRO E 4 148 ? 116.839 61.672  72.137  1.00 47.44  ? 136 PRO S CD    1 
ATOM   7909 N N     . VAL E 4 149 ? 119.272 64.797  69.593  1.00 48.28  ? 137 VAL S N     1 
ATOM   7910 C CA    . VAL E 4 149 ? 119.100 65.921  68.679  1.00 48.28  ? 137 VAL S CA    1 
ATOM   7911 C C     . VAL E 4 149 ? 120.391 66.101  67.898  1.00 48.28  ? 137 VAL S C     1 
ATOM   7912 O O     . VAL E 4 149 ? 121.464 65.682  68.337  1.00 48.28  ? 137 VAL S O     1 
ATOM   7913 C CB    . VAL E 4 149 ? 118.714 67.217  69.438  1.00 48.28  ? 137 VAL S CB    1 
ATOM   7914 C CG1   . VAL E 4 149 ? 119.817 67.619  70.407  1.00 48.28  ? 137 VAL S CG1   1 
ATOM   7915 C CG2   . VAL E 4 149 ? 118.427 68.337  68.449  1.00 48.28  ? 137 VAL S CG2   1 
ATOM   7916 N N     . THR E 4 150 ? 120.287 66.736  66.729  1.00 51.30  ? 138 THR S N     1 
ATOM   7917 C CA    . THR E 4 150 ? 121.431 67.057  65.894  1.00 51.30  ? 138 THR S CA    1 
ATOM   7918 C C     . THR E 4 150 ? 121.622 68.570  65.818  1.00 51.30  ? 138 THR S C     1 
ATOM   7919 O O     . THR E 4 150 ? 120.668 69.329  66.016  1.00 51.30  ? 138 THR S O     1 
ATOM   7920 C CB    . THR E 4 150 ? 121.260 66.504  64.474  1.00 51.30  ? 138 THR S CB    1 
ATOM   7921 O OG1   . THR E 4 150 ? 119.989 66.908  63.950  1.00 51.30  ? 138 THR S OG1   1 
ATOM   7922 C CG2   . THR E 4 150 ? 121.346 64.985  64.478  1.00 51.30  ? 138 THR S CG2   1 
ATOM   7923 N N     . PRO E 4 151 ? 122.836 69.042  65.536  1.00 53.52  ? 139 PRO S N     1 
ATOM   7924 C CA    . PRO E 4 151 ? 123.053 70.490  65.437  1.00 53.52  ? 139 PRO S CA    1 
ATOM   7925 C C     . PRO E 4 151 ? 122.147 71.119  64.388  1.00 53.52  ? 139 PRO S C     1 
ATOM   7926 O O     . PRO E 4 151 ? 121.876 70.532  63.338  1.00 53.52  ? 139 PRO S O     1 
ATOM   7927 C CB    . PRO E 4 151 ? 124.531 70.598  65.047  1.00 53.52  ? 139 PRO S CB    1 
ATOM   7928 C CG    . PRO E 4 151 ? 125.147 69.350  65.564  1.00 53.52  ? 139 PRO S CG    1 
ATOM   7929 C CD    . PRO E 4 151 ? 124.097 68.289  65.409  1.00 53.52  ? 139 PRO S CD    1 
ATOM   7930 N N     . GLY E 4 152 ? 121.674 72.329  64.686  1.00 53.77  ? 140 GLY S N     1 
ATOM   7931 C CA    . GLY E 4 152 ? 120.787 73.051  63.801  1.00 53.77  ? 140 GLY S CA    1 
ATOM   7932 C C     . GLY E 4 152 ? 119.313 72.797  64.027  1.00 53.77  ? 140 GLY S C     1 
ATOM   7933 O O     . GLY E 4 152 ? 118.483 73.491  63.424  1.00 53.77  ? 140 GLY S O     1 
ATOM   7934 N N     . GLU E 4 153 ? 118.957 71.836  64.875  1.00 52.63  ? 141 GLU S N     1 
ATOM   7935 C CA    . GLU E 4 153 ? 117.567 71.523  65.174  1.00 52.63  ? 141 GLU S CA    1 
ATOM   7936 C C     . GLU E 4 153 ? 117.201 72.107  66.532  1.00 52.63  ? 141 GLU S C     1 
ATOM   7937 O O     . GLU E 4 153 ? 117.856 71.813  67.537  1.00 52.63  ? 141 GLU S O     1 
ATOM   7938 C CB    . GLU E 4 153 ? 117.333 70.011  65.168  1.00 52.63  ? 141 GLU S CB    1 
ATOM   7939 C CG    . GLU E 4 153 ? 117.804 69.311  63.900  1.00 52.63  ? 141 GLU S CG    1 
ATOM   7940 C CD    . GLU E 4 153 ? 116.846 69.495  62.739  1.00 52.63  ? 141 GLU S CD    1 
ATOM   7941 O OE1   . GLU E 4 153 ? 115.663 69.810  62.983  1.00 52.63  ? 141 GLU S OE1   1 
ATOM   7942 O OE2   . GLU E 4 153 ? 117.278 69.324  61.580  1.00 52.63  ? 141 GLU S OE2   1 
ATOM   7943 N N     . SER E 4 154 ? 116.156 72.930  66.557  1.00 49.78  ? 142 SER S N     1 
ATOM   7944 C CA    . SER E 4 154 ? 115.756 73.592  67.788  1.00 49.78  ? 142 SER S CA    1 
ATOM   7945 C C     . SER E 4 154 ? 115.287 72.574  68.822  1.00 49.78  ? 142 SER S C     1 
ATOM   7946 O O     . SER E 4 154 ? 114.689 71.546  68.490  1.00 49.78  ? 142 SER S O     1 
ATOM   7947 C CB    . SER E 4 154 ? 114.646 74.605  67.512  1.00 49.78  ? 142 SER S CB    1 
ATOM   7948 O OG    . SER E 4 154 ? 115.018 75.496  66.476  1.00 49.78  ? 142 SER S OG    1 
ATOM   7949 N N     . VAL E 4 155 ? 115.566 72.872  70.089  1.00 44.10  ? 143 VAL S N     1 
ATOM   7950 C CA    . VAL E 4 155 ? 115.215 71.998  71.201  1.00 44.10  ? 143 VAL S CA    1 
ATOM   7951 C C     . VAL E 4 155 ? 114.343 72.767  72.181  1.00 44.10  ? 143 VAL S C     1 
ATOM   7952 O O     . VAL E 4 155 ? 114.394 73.999  72.257  1.00 44.10  ? 143 VAL S O     1 
ATOM   7953 C CB    . VAL E 4 155 ? 116.468 71.445  71.912  1.00 44.10  ? 143 VAL S CB    1 
ATOM   7954 C CG1   . VAL E 4 155 ? 116.081 70.362  72.905  1.00 44.10  ? 143 VAL S CG1   1 
ATOM   7955 C CG2   . VAL E 4 155 ? 117.448 70.909  70.893  1.00 44.10  ? 143 VAL S CG2   1 
ATOM   7956 N N     . SER E 4 156 ? 113.540 72.025  72.942  1.00 39.91  ? 144 SER S N     1 
ATOM   7957 C CA    . SER E 4 156 ? 112.640 72.600  73.936  1.00 39.91  ? 144 SER S CA    1 
ATOM   7958 C C     . SER E 4 156 ? 112.667 71.727  75.183  1.00 39.91  ? 144 SER S C     1 
ATOM   7959 O O     . SER E 4 156 ? 112.029 70.670  75.220  1.00 39.91  ? 144 SER S O     1 
ATOM   7960 C CB    . SER E 4 156 ? 111.219 72.720  73.386  1.00 39.91  ? 144 SER S CB    1 
ATOM   7961 O OG    . SER E 4 156 ? 110.311 73.101  74.403  1.00 39.91  ? 144 SER S OG    1 
ATOM   7962 N N     . ILE E 4 157 ? 113.404 72.168  76.197  1.00 33.57  ? 145 ILE S N     1 
ATOM   7963 C CA    . ILE E 4 157 ? 113.388 71.529  77.503  1.00 33.57  ? 145 ILE S CA    1 
ATOM   7964 C C     . ILE E 4 157 ? 112.204 72.084  78.284  1.00 33.57  ? 145 ILE S C     1 
ATOM   7965 O O     . ILE E 4 157 ? 111.717 73.182  78.014  1.00 33.57  ? 145 ILE S O     1 
ATOM   7966 C CB    . ILE E 4 157 ? 114.715 71.763  78.258  1.00 33.57  ? 145 ILE S CB    1 
ATOM   7967 C CG1   . ILE E 4 157 ? 115.898 71.228  77.448  1.00 33.57  ? 145 ILE S CG1   1 
ATOM   7968 C CG2   . ILE E 4 157 ? 114.679 71.109  79.632  1.00 33.57  ? 145 ILE S CG2   1 
ATOM   7969 C CD1   . ILE E 4 157 ? 116.058 69.729  77.512  1.00 33.57  ? 145 ILE S CD1   1 
ATOM   7970 N N     . SER E 4 158 ? 111.728 71.324  79.267  1.00 33.02  ? 146 SER S N     1 
ATOM   7971 C CA    . SER E 4 158 ? 110.606 71.785  80.072  1.00 33.02  ? 146 SER S CA    1 
ATOM   7972 C C     . SER E 4 158 ? 110.667 71.150  81.452  1.00 33.02  ? 146 SER S C     1 
ATOM   7973 O O     . SER E 4 158 ? 111.274 70.093  81.648  1.00 33.02  ? 146 SER S O     1 
ATOM   7974 C CB    . SER E 4 158 ? 109.265 71.463  79.403  1.00 33.02  ? 146 SER S CB    1 
ATOM   7975 O OG    . SER E 4 158 ? 109.025 70.067  79.387  1.00 33.02  ? 146 SER S OG    1 
ATOM   7976 N N     . CYS E 4 159 ? 110.029 71.817  82.411  1.00 32.46  ? 147 CYS S N     1 
ATOM   7977 C CA    . CYS E 4 159 ? 109.860 71.255  83.742  1.00 32.46  ? 147 CYS S CA    1 
ATOM   7978 C C     . CYS E 4 159 ? 108.634 71.871  84.405  1.00 32.46  ? 147 CYS S C     1 
ATOM   7979 O O     . CYS E 4 159 ? 108.183 72.964  84.041  1.00 32.46  ? 147 CYS S O     1 
ATOM   7980 C CB    . CYS E 4 159 ? 111.118 71.451  84.609  1.00 32.46  ? 147 CYS S CB    1 
ATOM   7981 S SG    . CYS E 4 159 ? 111.440 73.124  85.230  1.00 32.46  ? 147 CYS S SG    1 
ATOM   7982 N N     . ARG E 4 160 ? 108.102 71.146  85.386  1.00 32.39  ? 148 ARG S N     1 
ATOM   7983 C CA    . ARG E 4 160 ? 106.895 71.518  86.105  1.00 32.39  ? 148 ARG S CA    1 
ATOM   7984 C C     . ARG E 4 160 ? 107.224 71.767  87.571  1.00 32.39  ? 148 ARG S C     1 
ATOM   7985 O O     . ARG E 4 160 ? 108.183 71.215  88.115  1.00 32.39  ? 148 ARG S O     1 
ATOM   7986 C CB    . ARG E 4 160 ? 105.830 70.420  85.997  1.00 32.39  ? 148 ARG S CB    1 
ATOM   7987 C CG    . ARG E 4 160 ? 105.433 70.046  84.574  1.00 32.39  ? 148 ARG S CG    1 
ATOM   7988 C CD    . ARG E 4 160 ? 104.247 70.858  84.073  1.00 32.39  ? 148 ARG S CD    1 
ATOM   7989 N NE    . ARG E 4 160 ? 103.545 70.179  82.988  1.00 32.39  ? 148 ARG S NE    1 
ATOM   7990 C CZ    . ARG E 4 160 ? 103.660 70.476  81.700  1.00 32.39  ? 148 ARG S CZ    1 
ATOM   7991 N NH1   . ARG E 4 160 ? 104.478 71.427  81.275  1.00 32.39  ? 148 ARG S NH1   1 
ATOM   7992 N NH2   . ARG E 4 160 ? 102.941 69.796  80.812  1.00 32.39  ? 148 ARG S NH2   1 
ATOM   7993 N N     . SER E 4 161 ? 106.401 72.597  88.210  1.00 27.93  ? 149 SER S N     1 
ATOM   7994 C CA    . SER E 4 161 ? 106.569 72.950  89.612  1.00 27.93  ? 149 SER S CA    1 
ATOM   7995 C C     . SER E 4 161 ? 105.266 72.707  90.362  1.00 27.93  ? 149 SER S C     1 
ATOM   7996 O O     . SER E 4 161 ? 104.191 72.598  89.767  1.00 27.93  ? 149 SER S O     1 
ATOM   7997 C CB    . SER E 4 161 ? 106.997 74.414  89.777  1.00 27.93  ? 149 SER S CB    1 
ATOM   7998 O OG    . SER E 4 161 ? 105.927 75.295  89.483  1.00 27.93  ? 149 SER S OG    1 
ATOM   7999 N N     . SER E 4 162 ? 105.376 72.625  91.689  1.00 26.20  ? 150 SER S N     1 
ATOM   8000 C CA    . SER E 4 162 ? 104.210 72.348  92.523  1.00 26.20  ? 150 SER S CA    1 
ATOM   8001 C C     . SER E 4 162 ? 103.334 73.587  92.681  1.00 26.20  ? 150 SER S C     1 
ATOM   8002 O O     . SER E 4 162 ? 102.168 73.591  92.273  1.00 26.20  ? 150 SER S O     1 
ATOM   8003 C CB    . SER E 4 162 ? 104.659 71.832  93.893  1.00 26.20  ? 150 SER S CB    1 
ATOM   8004 O OG    . SER E 4 162 ? 105.484 70.689  93.761  1.00 26.20  ? 150 SER S OG    1 
ATOM   8005 N N     . LYS E 4 163 ? 103.881 74.648  93.270  1.00 25.08  ? 151 LYS S N     1 
ATOM   8006 C CA    . LYS E 4 163 ? 103.138 75.883  93.456  1.00 25.08  ? 151 LYS S CA    1 
ATOM   8007 C C     . LYS E 4 163 ? 103.350 76.814  92.267  1.00 25.08  ? 151 LYS S C     1 
ATOM   8008 O O     . LYS E 4 163 ? 104.035 76.488  91.294  1.00 25.08  ? 151 LYS S O     1 
ATOM   8009 C CB    . LYS E 4 163 ? 103.555 76.591  94.746  1.00 25.08  ? 151 LYS S CB    1 
ATOM   8010 C CG    . LYS E 4 163 ? 103.766 75.690  95.951  1.00 25.08  ? 151 LYS S CG    1 
ATOM   8011 C CD    . LYS E 4 163 ? 104.366 76.447  97.142  1.00 25.08  ? 151 LYS S CD    1 
ATOM   8012 C CE    . LYS E 4 163 ? 103.675 77.782  97.424  1.00 25.08  ? 151 LYS S CE    1 
ATOM   8013 N NZ    . LYS E 4 163 ? 104.385 78.558  98.477  1.00 25.08  ? 151 LYS S NZ    1 
ATOM   8014 N N     . SER E 4 164 ? 102.750 77.998  92.351  1.00 24.44  ? 152 SER S N     1 
ATOM   8015 C CA    . SER E 4 164 ? 102.958 79.052  91.368  1.00 24.44  ? 152 SER S CA    1 
ATOM   8016 C C     . SER E 4 164 ? 104.156 79.883  91.810  1.00 24.44  ? 152 SER S C     1 
ATOM   8017 O O     . SER E 4 164 ? 104.091 80.588  92.822  1.00 24.44  ? 152 SER S O     1 
ATOM   8018 C CB    . SER E 4 164 ? 101.709 79.918  91.231  1.00 24.44  ? 152 SER S CB    1 
ATOM   8019 O OG    . SER E 4 164 ? 101.853 80.854  90.178  1.00 24.44  ? 152 SER S OG    1 
ATOM   8020 N N     . LEU E 4 165 ? 105.254 79.793  91.058  1.00 21.25  ? 153 LEU S N     1 
ATOM   8021 C CA    . LEU E 4 165 ? 106.423 80.607  91.360  1.00 21.25  ? 153 LEU S CA    1 
ATOM   8022 C C     . LEU E 4 165 ? 106.161 82.089  91.133  1.00 21.25  ? 153 LEU S C     1 
ATOM   8023 O O     . LEU E 4 165 ? 106.931 82.924  91.619  1.00 21.25  ? 153 LEU S O     1 
ATOM   8024 C CB    . LEU E 4 165 ? 107.612 80.140  90.521  1.00 21.25  ? 153 LEU S CB    1 
ATOM   8025 C CG    . LEU E 4 165 ? 108.048 78.694  90.770  1.00 21.25  ? 153 LEU S CG    1 
ATOM   8026 C CD1   . LEU E 4 165 ? 109.199 78.310  89.863  1.00 21.25  ? 153 LEU S CD1   1 
ATOM   8027 C CD2   . LEU E 4 165 ? 108.437 78.491  92.227  1.00 21.25  ? 153 LEU S CD2   1 
ATOM   8028 N N     . LEU E 4 166 ? 105.091 82.432  90.416  1.00 21.12  ? 154 LEU S N     1 
ATOM   8029 C CA    . LEU E 4 166 ? 104.716 83.824  90.205  1.00 21.12  ? 154 LEU S CA    1 
ATOM   8030 C C     . LEU E 4 166 ? 104.298 84.471  91.519  1.00 21.12  ? 154 LEU S C     1 
ATOM   8031 O O     . LEU E 4 166 ? 103.238 84.149  92.067  1.00 21.12  ? 154 LEU S O     1 
ATOM   8032 C CB    . LEU E 4 166 ? 103.583 83.918  89.182  1.00 21.12  ? 154 LEU S CB    1 
ATOM   8033 C CG    . LEU E 4 166 ? 103.215 85.322  88.697  1.00 21.12  ? 154 LEU S CG    1 
ATOM   8034 C CD1   . LEU E 4 166 ? 102.807 85.285  87.234  1.00 21.12  ? 154 LEU S CD1   1 
ATOM   8035 C CD2   . LEU E 4 166 ? 102.102 85.918  89.544  1.00 21.12  ? 154 LEU S CD2   1 
ATOM   8036 N N     . HIS E 4 167 ? 105.123 85.382  92.031  1.00 18.13  ? 155 HIS S N     1 
ATOM   8037 C CA    . HIS E 4 167 ? 104.833 86.075  93.275  1.00 18.13  ? 155 HIS S CA    1 
ATOM   8038 C C     . HIS E 4 167 ? 104.024 87.342  92.997  1.00 18.13  ? 155 HIS S C     1 
ATOM   8039 O O     . HIS E 4 167 ? 103.775 87.718  91.849  1.00 18.13  ? 155 HIS S O     1 
ATOM   8040 C CB    . HIS E 4 167 ? 106.132 86.401  94.009  1.00 18.13  ? 155 HIS S CB    1 
ATOM   8041 C CG    . HIS E 4 167 ? 105.952 86.678  95.469  1.00 18.13  ? 155 HIS S CG    1 
ATOM   8042 N ND1   . HIS E 4 167 ? 105.810 87.953  95.971  1.00 18.13  ? 155 HIS S ND1   1 
ATOM   8043 C CD2   . HIS E 4 167 ? 105.888 85.845  96.535  1.00 18.13  ? 155 HIS S CD2   1 
ATOM   8044 C CE1   . HIS E 4 167 ? 105.668 87.894  97.283  1.00 18.13  ? 155 HIS S CE1   1 
ATOM   8045 N NE2   . HIS E 4 167 ? 105.712 86.626  97.650  1.00 18.13  ? 155 HIS S NE2   1 
ATOM   8046 N N     . SER E 4 168 ? 103.599 88.009  94.073  1.00 19.07  ? 156 SER S N     1 
ATOM   8047 C CA    . SER E 4 168 ? 102.878 89.268  93.937  1.00 19.07  ? 156 SER S CA    1 
ATOM   8048 C C     . SER E 4 168 ? 103.717 90.342  93.258  1.00 19.07  ? 156 SER S C     1 
ATOM   8049 O O     . SER E 4 168 ? 103.154 91.292  92.704  1.00 19.07  ? 156 SER S O     1 
ATOM   8050 C CB    . SER E 4 168 ? 102.423 89.759  95.311  1.00 19.07  ? 156 SER S CB    1 
ATOM   8051 O OG    . SER E 4 168 ? 103.510 89.799  96.218  1.00 19.07  ? 156 SER S OG    1 
ATOM   8052 N N     . ASN E 4 169 ? 105.045 90.216  93.291  1.00 17.94  ? 157 ASN S N     1 
ATOM   8053 C CA    . ASN E 4 169 ? 105.904 91.169  92.600  1.00 17.94  ? 157 ASN S CA    1 
ATOM   8054 C C     . ASN E 4 169 ? 105.722 91.121  91.091  1.00 17.94  ? 157 ASN S C     1 
ATOM   8055 O O     . ASN E 4 169 ? 106.127 92.062  90.400  1.00 17.94  ? 157 ASN S O     1 
ATOM   8056 C CB    . ASN E 4 169 ? 107.371 90.895  92.929  1.00 17.94  ? 157 ASN S CB    1 
ATOM   8057 C CG    . ASN E 4 169 ? 107.629 90.816  94.412  1.00 17.94  ? 157 ASN S CG    1 
ATOM   8058 O OD1   . ASN E 4 169 ? 108.242 89.865  94.894  1.00 17.94  ? 157 ASN S OD1   1 
ATOM   8059 N ND2   . ASN E 4 169 ? 107.162 91.814  95.150  1.00 17.94  ? 157 ASN S ND2   1 
ATOM   8060 N N     . GLY E 4 170 ? 105.125 90.056  90.568  1.00 18.67  ? 158 GLY S N     1 
ATOM   8061 C CA    . GLY E 4 170 ? 105.128 89.795  89.147  1.00 18.67  ? 158 GLY S CA    1 
ATOM   8062 C C     . GLY E 4 170 ? 106.328 89.014  88.668  1.00 18.67  ? 158 GLY S C     1 
ATOM   8063 O O     . GLY E 4 170 ? 106.420 88.729  87.468  1.00 18.67  ? 158 GLY S O     1 
ATOM   8064 N N     . ASN E 4 171 ? 107.245 88.658  89.564  1.00 18.53  ? 159 ASN S N     1 
ATOM   8065 C CA    . ASN E 4 171 ? 108.438 87.897  89.223  1.00 18.53  ? 159 ASN S CA    1 
ATOM   8066 C C     . ASN E 4 171 ? 108.146 86.413  89.400  1.00 18.53  ? 159 ASN S C     1 
ATOM   8067 O O     . ASN E 4 171 ? 107.718 85.986  90.478  1.00 18.53  ? 159 ASN S O     1 
ATOM   8068 C CB    . ASN E 4 171 ? 109.618 88.310  90.103  1.00 18.53  ? 159 ASN S CB    1 
ATOM   8069 C CG    . ASN E 4 171 ? 110.092 89.720  89.823  1.00 18.53  ? 159 ASN S CG    1 
ATOM   8070 O OD1   . ASN E 4 171 ? 110.220 90.534  90.736  1.00 18.53  ? 159 ASN S OD1   1 
ATOM   8071 N ND2   . ASN E 4 171 ? 110.359 90.016  88.558  1.00 18.53  ? 159 ASN S ND2   1 
ATOM   8072 N N     . THR E 4 172 ? 108.375 85.634  88.346  1.00 20.53  ? 160 THR S N     1 
ATOM   8073 C CA    . THR E 4 172 ? 108.285 84.177  88.422  1.00 20.53  ? 160 THR S CA    1 
ATOM   8074 C C     . THR E 4 172 ? 109.689 83.662  88.700  1.00 20.53  ? 160 THR S C     1 
ATOM   8075 O O     . THR E 4 172 ? 110.511 83.509  87.796  1.00 20.53  ? 160 THR S O     1 
ATOM   8076 C CB    . THR E 4 172 ? 107.710 83.595  87.137  1.00 20.53  ? 160 THR S CB    1 
ATOM   8077 O OG1   . THR E 4 172 ? 106.596 84.387  86.706  1.00 20.53  ? 160 THR S OG1   1 
ATOM   8078 C CG2   . THR E 4 172 ? 107.255 82.159  87.358  1.00 20.53  ? 160 THR S CG2   1 
ATOM   8079 N N     . TYR E 4 173 ? 109.966 83.385  89.972  1.00 17.18  ? 161 TYR S N     1 
ATOM   8080 C CA    . TYR E 4 173 ? 111.320 83.063  90.401  1.00 17.18  ? 161 TYR S CA    1 
ATOM   8081 C C     . TYR E 4 173 ? 111.716 81.649  90.000  1.00 17.18  ? 161 TYR S C     1 
ATOM   8082 O O     . TYR E 4 173 ? 111.965 80.799  90.861  1.00 17.18  ? 161 TYR S O     1 
ATOM   8083 C CB    . TYR E 4 173 ? 111.450 83.235  91.915  1.00 17.18  ? 161 TYR S CB    1 
ATOM   8084 C CG    . TYR E 4 173 ? 111.239 84.655  92.385  1.00 17.18  ? 161 TYR S CG    1 
ATOM   8085 C CD1   . TYR E 4 173 ? 112.027 85.688  91.901  1.00 17.18  ? 161 TYR S CD1   1 
ATOM   8086 C CD2   . TYR E 4 173 ? 110.257 84.962  93.314  1.00 17.18  ? 161 TYR S CD2   1 
ATOM   8087 C CE1   . TYR E 4 173 ? 111.842 86.986  92.325  1.00 17.18  ? 161 TYR S CE1   1 
ATOM   8088 C CE2   . TYR E 4 173 ? 110.065 86.259  93.745  1.00 17.18  ? 161 TYR S CE2   1 
ATOM   8089 C CZ    . TYR E 4 173 ? 110.860 87.267  93.247  1.00 17.18  ? 161 TYR S CZ    1 
ATOM   8090 O OH    . TYR E 4 173 ? 110.675 88.562  93.672  1.00 17.18  ? 161 TYR S OH    1 
ATOM   8091 N N     . LEU E 4 174 ? 111.777 81.392  88.698  1.00 20.40  ? 162 LEU S N     1 
ATOM   8092 C CA    . LEU E 4 174 ? 112.318 80.150  88.165  1.00 20.40  ? 162 LEU S CA    1 
ATOM   8093 C C     . LEU E 4 174 ? 113.582 80.457  87.378  1.00 20.40  ? 162 LEU S C     1 
ATOM   8094 O O     . LEU E 4 174 ? 113.616 81.406  86.590  1.00 20.40  ? 162 LEU S O     1 
ATOM   8095 C CB    . LEU E 4 174 ? 111.295 79.431  87.286  1.00 20.40  ? 162 LEU S CB    1 
ATOM   8096 C CG    . LEU E 4 174 ? 111.708 78.032  86.819  1.00 20.40  ? 162 LEU S CG    1 
ATOM   8097 C CD1   . LEU E 4 174 ? 110.489 77.184  86.635  1.00 20.40  ? 162 LEU S CD1   1 
ATOM   8098 C CD2   . LEU E 4 174 ? 112.474 78.081  85.505  1.00 20.40  ? 162 LEU S CD2   1 
ATOM   8099 N N     . TYR E 4 175 ? 114.612 79.652  87.594  1.00 18.98  ? 163 TYR S N     1 
ATOM   8100 C CA    . TYR E 4 175 ? 115.923 79.877  87.015  1.00 18.98  ? 163 TYR S CA    1 
ATOM   8101 C C     . TYR E 4 175 ? 116.186 78.802  85.966  1.00 18.98  ? 163 TYR S C     1 
ATOM   8102 O O     . TYR E 4 175 ? 115.435 77.834  85.833  1.00 18.98  ? 163 TYR S O     1 
ATOM   8103 C CB    . TYR E 4 175 ? 116.992 79.834  88.110  1.00 18.98  ? 163 TYR S CB    1 
ATOM   8104 C CG    . TYR E 4 175 ? 116.900 80.972  89.103  1.00 18.98  ? 163 TYR S CG    1 
ATOM   8105 C CD1   . TYR E 4 175 ? 116.132 82.096  88.849  1.00 18.98  ? 163 TYR S CD1   1 
ATOM   8106 C CD2   . TYR E 4 175 ? 117.561 80.906  90.314  1.00 18.98  ? 163 TYR S CD2   1 
ATOM   8107 C CE1   . TYR E 4 175 ? 116.035 83.117  89.777  1.00 18.98  ? 163 TYR S CE1   1 
ATOM   8108 C CE2   . TYR E 4 175 ? 117.471 81.928  91.237  1.00 18.98  ? 163 TYR S CE2   1 
ATOM   8109 C CZ    . TYR E 4 175 ? 116.713 83.032  90.960  1.00 18.98  ? 163 TYR S CZ    1 
ATOM   8110 O OH    . TYR E 4 175 ? 116.621 84.053  91.878  1.00 18.98  ? 163 TYR S OH    1 
ATOM   8111 N N     . TRP E 4 176 ? 117.275 78.972  85.220  1.00 22.91  ? 164 TRP S N     1 
ATOM   8112 C CA    . TRP E 4 176 ? 117.642 77.990  84.201  1.00 22.91  ? 164 TRP S CA    1 
ATOM   8113 C C     . TRP E 4 176 ? 119.162 77.991  84.080  1.00 22.91  ? 164 TRP S C     1 
ATOM   8114 O O     . TRP E 4 176 ? 119.743 78.982  83.620  1.00 22.91  ? 164 TRP S O     1 
ATOM   8115 C CB    . TRP E 4 176 ? 116.983 78.307  82.867  1.00 22.91  ? 164 TRP S CB    1 
ATOM   8116 C CG    . TRP E 4 176 ? 115.722 77.551  82.605  1.00 22.91  ? 164 TRP S CG    1 
ATOM   8117 C CD1   . TRP E 4 176 ? 114.488 78.077  82.366  1.00 22.91  ? 164 TRP S CD1   1 
ATOM   8118 C CD2   . TRP E 4 176 ? 115.572 76.128  82.543  1.00 22.91  ? 164 TRP S CD2   1 
ATOM   8119 N NE1   . TRP E 4 176 ? 113.576 77.070  82.162  1.00 22.91  ? 164 TRP S NE1   1 
ATOM   8120 C CE2   . TRP E 4 176 ? 114.217 75.864  82.265  1.00 22.91  ? 164 TRP S CE2   1 
ATOM   8121 C CE3   . TRP E 4 176 ? 116.451 75.053  82.695  1.00 22.91  ? 164 TRP S CE3   1 
ATOM   8122 C CZ2   . TRP E 4 176 ? 113.721 74.570  82.138  1.00 22.91  ? 164 TRP S CZ2   1 
ATOM   8123 C CZ3   . TRP E 4 176 ? 115.957 73.770  82.569  1.00 22.91  ? 164 TRP S CZ3   1 
ATOM   8124 C CH2   . TRP E 4 176 ? 114.605 73.539  82.292  1.00 22.91  ? 164 TRP S CH2   1 
ATOM   8125 N N     . PHE E 4 177 ? 119.781 76.883  84.489  1.00 20.29  ? 165 PHE S N     1 
ATOM   8126 C CA    . PHE E 4 177 ? 121.211 76.650  84.353  1.00 20.29  ? 165 PHE S CA    1 
ATOM   8127 C C     . PHE E 4 177 ? 121.468 75.525  83.354  1.00 20.29  ? 165 PHE S C     1 
ATOM   8128 O O     . PHE E 4 177 ? 120.626 74.652  83.124  1.00 20.29  ? 165 PHE S O     1 
ATOM   8129 C CB    . PHE E 4 177 ? 121.847 76.278  85.698  1.00 20.29  ? 165 PHE S CB    1 
ATOM   8130 C CG    . PHE E 4 177 ? 121.339 77.072  86.866  1.00 20.29  ? 165 PHE S CG    1 
ATOM   8131 C CD1   . PHE E 4 177 ? 120.194 76.683  87.539  1.00 20.29  ? 165 PHE S CD1   1 
ATOM   8132 C CD2   . PHE E 4 177 ? 122.022 78.189  87.309  1.00 20.29  ? 165 PHE S CD2   1 
ATOM   8133 C CE1   . PHE E 4 177 ? 119.731 77.406  88.619  1.00 20.29  ? 165 PHE S CE1   1 
ATOM   8134 C CE2   . PHE E 4 177 ? 121.564 78.914  88.389  1.00 20.29  ? 165 PHE S CE2   1 
ATOM   8135 C CZ    . PHE E 4 177 ? 120.419 78.522  89.045  1.00 20.29  ? 165 PHE S CZ    1 
ATOM   8136 N N     . LEU E 4 178 ? 122.664 75.545  82.771  1.00 26.21  ? 166 LEU S N     1 
ATOM   8137 C CA    . LEU E 4 178 ? 123.117 74.463  81.903  1.00 26.21  ? 166 LEU S CA    1 
ATOM   8138 C C     . LEU E 4 178 ? 124.488 74.012  82.378  1.00 26.21  ? 166 LEU S C     1 
ATOM   8139 O O     . LEU E 4 178 ? 125.403 74.831  82.501  1.00 26.21  ? 166 LEU S O     1 
ATOM   8140 C CB    . LEU E 4 178 ? 123.167 74.908  80.439  1.00 26.21  ? 166 LEU S CB    1 
ATOM   8141 C CG    . LEU E 4 178 ? 123.854 73.958  79.452  1.00 26.21  ? 166 LEU S CG    1 
ATOM   8142 C CD1   . LEU E 4 178 ? 123.008 72.718  79.217  1.00 26.21  ? 166 LEU S CD1   1 
ATOM   8143 C CD2   . LEU E 4 178 ? 124.131 74.671  78.140  1.00 26.21  ? 166 LEU S CD2   1 
ATOM   8144 N N     . GLN E 4 179 ? 124.624 72.716  82.644  1.00 25.62  ? 167 GLN S N     1 
ATOM   8145 C CA    . GLN E 4 179 ? 125.886 72.115  83.055  1.00 25.62  ? 167 GLN S CA    1 
ATOM   8146 C C     . GLN E 4 179 ? 126.438 71.321  81.879  1.00 25.62  ? 167 GLN S C     1 
ATOM   8147 O O     . GLN E 4 179 ? 125.862 70.301  81.484  1.00 25.62  ? 167 GLN S O     1 
ATOM   8148 C CB    . GLN E 4 179 ? 125.687 71.223  84.277  1.00 25.62  ? 167 GLN S CB    1 
ATOM   8149 C CG    . GLN E 4 179 ? 126.966 70.611  84.807  1.00 25.62  ? 167 GLN S CG    1 
ATOM   8150 C CD    . GLN E 4 179 ? 126.842 70.173  86.248  1.00 25.62  ? 167 GLN S CD    1 
ATOM   8151 O OE1   . GLN E 4 179 ? 125.841 69.577  86.641  1.00 25.62  ? 167 GLN S OE1   1 
ATOM   8152 N NE2   . GLN E 4 179 ? 127.864 70.462  87.045  1.00 25.62  ? 167 GLN S NE2   1 
ATOM   8153 N N     . ARG E 4 180 ? 127.547 71.798  81.312  1.00 31.77  ? 168 ARG S N     1 
ATOM   8154 C CA    . ARG E 4 180 ? 128.188 71.129  80.194  1.00 31.77  ? 168 ARG S CA    1 
ATOM   8155 C C     . ARG E 4 180 ? 129.061 69.982  80.691  1.00 31.77  ? 168 ARG S C     1 
ATOM   8156 O O     . ARG E 4 180 ? 129.508 69.989  81.842  1.00 31.77  ? 168 ARG S O     1 
ATOM   8157 C CB    . ARG E 4 180 ? 129.043 72.116  79.405  1.00 31.77  ? 168 ARG S CB    1 
ATOM   8158 C CG    . ARG E 4 180 ? 128.250 73.026  78.483  1.00 31.77  ? 168 ARG S CG    1 
ATOM   8159 C CD    . ARG E 4 180 ? 129.141 74.078  77.844  1.00 31.77  ? 168 ARG S CD    1 
ATOM   8160 N NE    . ARG E 4 180 ? 128.363 75.096  77.145  1.00 31.77  ? 168 ARG S NE    1 
ATOM   8161 C CZ    . ARG E 4 180 ? 128.343 76.388  77.450  1.00 31.77  ? 168 ARG S CZ    1 
ATOM   8162 N NH1   . ARG E 4 180 ? 129.047 76.878  78.458  1.00 31.77  ? 168 ARG S NH1   1 
ATOM   8163 N NH2   . ARG E 4 180 ? 127.592 77.212  76.725  1.00 31.77  ? 168 ARG S NH2   1 
ATOM   8164 N N     . PRO E 4 181 ? 129.313 68.977  79.846  1.00 35.83  ? 169 PRO S N     1 
ATOM   8165 C CA    . PRO E 4 181 ? 130.137 67.839  80.280  1.00 35.83  ? 169 PRO S CA    1 
ATOM   8166 C C     . PRO E 4 181 ? 131.463 68.258  80.894  1.00 35.83  ? 169 PRO S C     1 
ATOM   8167 O O     . PRO E 4 181 ? 132.267 68.940  80.252  1.00 35.83  ? 169 PRO S O     1 
ATOM   8168 C CB    . PRO E 4 181 ? 130.360 67.042  78.987  1.00 35.83  ? 169 PRO S CB    1 
ATOM   8169 C CG    . PRO E 4 181 ? 129.351 67.529  78.006  1.00 35.83  ? 169 PRO S CG    1 
ATOM   8170 C CD    . PRO E 4 181 ? 128.660 68.740  78.548  1.00 35.83  ? 169 PRO S CD    1 
ATOM   8171 N N     . GLY E 4 182 ? 131.698 67.854  82.141  1.00 35.62  ? 170 GLY S N     1 
ATOM   8172 C CA    . GLY E 4 182 ? 132.995 68.049  82.757  1.00 35.62  ? 170 GLY S CA    1 
ATOM   8173 C C     . GLY E 4 182 ? 133.291 69.454  83.227  1.00 35.62  ? 170 GLY S C     1 
ATOM   8174 O O     . GLY E 4 182 ? 134.457 69.780  83.462  1.00 35.62  ? 170 GLY S O     1 
ATOM   8175 N N     . GLN E 4 183 ? 132.275 70.302  83.373  1.00 30.19  ? 171 GLN S N     1 
ATOM   8176 C CA    . GLN E 4 183 ? 132.475 71.656  83.868  1.00 30.19  ? 171 GLN S CA    1 
ATOM   8177 C C     . GLN E 4 183 ? 131.260 72.087  84.677  1.00 30.19  ? 171 GLN S C     1 
ATOM   8178 O O     . GLN E 4 183 ? 130.172 71.516  84.562  1.00 30.19  ? 171 GLN S O     1 
ATOM   8179 C CB    . GLN E 4 183 ? 132.744 72.643  82.724  1.00 30.19  ? 171 GLN S CB    1 
ATOM   8180 C CG    . GLN E 4 183 ? 131.859 72.462  81.507  1.00 30.19  ? 171 GLN S CG    1 
ATOM   8181 C CD    . GLN E 4 183 ? 132.068 73.553  80.477  1.00 30.19  ? 171 GLN S CD    1 
ATOM   8182 O OE1   . GLN E 4 183 ? 132.403 74.687  80.816  1.00 30.19  ? 171 GLN S OE1   1 
ATOM   8183 N NE2   . GLN E 4 183 ? 131.886 73.212  79.208  1.00 30.19  ? 171 GLN S NE2   1 
ATOM   8184 N N     . SER E 4 184 ? 131.464 73.111  85.500  1.00 22.43  ? 172 SER S N     1 
ATOM   8185 C CA    . SER E 4 184 ? 130.457 73.510  86.469  1.00 22.43  ? 172 SER S CA    1 
ATOM   8186 C C     . SER E 4 184 ? 129.250 74.138  85.771  1.00 22.43  ? 172 SER S C     1 
ATOM   8187 O O     . SER E 4 184 ? 129.341 74.564  84.616  1.00 22.43  ? 172 SER S O     1 
ATOM   8188 C CB    . SER E 4 184 ? 131.048 74.496  87.472  1.00 22.43  ? 172 SER S CB    1 
ATOM   8189 O OG    . SER E 4 184 ? 131.824 75.486  86.822  1.00 22.43  ? 172 SER S OG    1 
ATOM   8190 N N     . PRO E 4 185 ? 128.106 74.209  86.451  1.00 20.43  ? 173 PRO S N     1 
ATOM   8191 C CA    . PRO E 4 185 ? 126.904 74.755  85.815  1.00 20.43  ? 173 PRO S CA    1 
ATOM   8192 C C     . PRO E 4 185 ? 127.080 76.218  85.438  1.00 20.43  ? 173 PRO S C     1 
ATOM   8193 O O     . PRO E 4 185 ? 127.887 76.949  86.016  1.00 20.43  ? 173 PRO S O     1 
ATOM   8194 C CB    . PRO E 4 185 ? 125.821 74.584  86.889  1.00 20.43  ? 173 PRO S CB    1 
ATOM   8195 C CG    . PRO E 4 185 ? 126.352 73.541  87.807  1.00 20.43  ? 173 PRO S CG    1 
ATOM   8196 C CD    . PRO E 4 185 ? 127.829 73.753  87.823  1.00 20.43  ? 173 PRO S CD    1 
ATOM   8197 N N     . GLN E 4 186 ? 126.304 76.638  84.443  1.00 21.67  ? 174 GLN S N     1 
ATOM   8198 C CA    . GLN E 4 186 ? 126.335 78.005  83.949  1.00 21.67  ? 174 GLN S CA    1 
ATOM   8199 C C     . GLN E 4 186 ? 124.915 78.543  83.885  1.00 21.67  ? 174 GLN S C     1 
ATOM   8200 O O     . GLN E 4 186 ? 124.007 77.863  83.402  1.00 21.67  ? 174 GLN S O     1 
ATOM   8201 C CB    . GLN E 4 186 ? 126.985 78.085  82.562  1.00 21.67  ? 174 GLN S CB    1 
ATOM   8202 C CG    . GLN E 4 186 ? 127.336 79.495  82.123  1.00 21.67  ? 174 GLN S CG    1 
ATOM   8203 C CD    . GLN E 4 186 ? 127.072 79.729  80.648  1.00 21.67  ? 174 GLN S CD    1 
ATOM   8204 O OE1   . GLN E 4 186 ? 125.984 79.443  80.147  1.00 21.67  ? 174 GLN S OE1   1 
ATOM   8205 N NE2   . GLN E 4 186 ? 128.068 80.252  79.943  1.00 21.67  ? 174 GLN S NE2   1 
ATOM   8206 N N     . LEU E 4 187 ? 124.730 79.763  84.378  1.00 19.21  ? 175 LEU S N     1 
ATOM   8207 C CA    . LEU E 4 187 ? 123.421 80.394  84.334  1.00 19.21  ? 175 LEU S CA    1 
ATOM   8208 C C     . LEU E 4 187 ? 123.031 80.724  82.900  1.00 19.21  ? 175 LEU S C     1 
ATOM   8209 O O     . LEU E 4 187 ? 123.847 81.185  82.098  1.00 19.21  ? 175 LEU S O     1 
ATOM   8210 C CB    . LEU E 4 187 ? 123.414 81.671  85.174  1.00 19.21  ? 175 LEU S CB    1 
ATOM   8211 C CG    . LEU E 4 187 ? 122.077 82.418  85.232  1.00 19.21  ? 175 LEU S CG    1 
ATOM   8212 C CD1   . LEU E 4 187 ? 121.049 81.626  86.023  1.00 19.21  ? 175 LEU S CD1   1 
ATOM   8213 C CD2   . LEU E 4 187 ? 122.251 83.806  85.817  1.00 19.21  ? 175 LEU S CD2   1 
ATOM   8214 N N     . LEU E 4 188 ? 121.774 80.482  82.585  1.00 23.33  ? 176 LEU S N     1 
ATOM   8215 C CA    . LEU E 4 188 ? 121.198 80.886  81.309  1.00 23.33  ? 176 LEU S CA    1 
ATOM   8216 C C     . LEU E 4 188 ? 120.076 81.896  81.476  1.00 23.33  ? 176 LEU S C     1 
ATOM   8217 O O     . LEU E 4 188 ? 120.073 82.917  80.786  1.00 23.33  ? 176 LEU S O     1 
ATOM   8218 C CB    . LEU E 4 188 ? 120.670 79.664  80.543  1.00 23.33  ? 176 LEU S CB    1 
ATOM   8219 C CG    . LEU E 4 188 ? 121.606 78.463  80.425  1.00 23.33  ? 176 LEU S CG    1 
ATOM   8220 C CD1   . LEU E 4 188 ? 120.874 77.309  79.766  1.00 23.33  ? 176 LEU S CD1   1 
ATOM   8221 C CD2   . LEU E 4 188 ? 122.861 78.823  79.651  1.00 23.33  ? 176 LEU S CD2   1 
ATOM   8222 N N     . ILE E 4 189 ? 119.127 81.638  82.371  1.00 22.79  ? 177 ILE S N     1 
ATOM   8223 C CA    . ILE E 4 189 ? 118.007 82.544  82.610  1.00 22.79  ? 177 ILE S CA    1 
ATOM   8224 C C     . ILE E 4 189 ? 117.857 82.733  84.110  1.00 22.79  ? 177 ILE S C     1 
ATOM   8225 O O     . ILE E 4 189 ? 117.986 81.772  84.875  1.00 22.79  ? 177 ILE S O     1 
ATOM   8226 C CB    . ILE E 4 189 ? 116.692 82.009  82.005  1.00 22.79  ? 177 ILE S CB    1 
ATOM   8227 C CG1   . ILE E 4 189 ? 116.876 81.644  80.527  1.00 22.79  ? 177 ILE S CG1   1 
ATOM   8228 C CG2   . ILE E 4 189 ? 115.576 83.019  82.182  1.00 22.79  ? 177 ILE S CG2   1 
ATOM   8229 C CD1   . ILE E 4 189 ? 117.099 82.823  79.619  1.00 22.79  ? 177 ILE S CD1   1 
ATOM   8230 N N     . TYR E 4 190 ? 117.558 83.966  84.534  1.00 18.56  ? 178 TYR S N     1 
ATOM   8231 C CA    . TYR E 4 190 ? 117.461 84.255  85.958  1.00 18.56  ? 178 TYR S CA    1 
ATOM   8232 C C     . TYR E 4 190 ? 116.080 84.682  86.440  1.00 18.56  ? 178 TYR S C     1 
ATOM   8233 O O     . TYR E 4 190 ? 115.866 84.695  87.652  1.00 18.56  ? 178 TYR S O     1 
ATOM   8234 C CB    . TYR E 4 190 ? 118.494 85.314  86.380  1.00 18.56  ? 178 TYR S CB    1 
ATOM   8235 C CG    . TYR E 4 190 ? 118.529 86.583  85.567  1.00 18.56  ? 178 TYR S CG    1 
ATOM   8236 C CD1   . TYR E 4 190 ? 117.556 87.559  85.724  1.00 18.56  ? 178 TYR S CD1   1 
ATOM   8237 C CD2   . TYR E 4 190 ? 119.562 86.823  84.671  1.00 18.56  ? 178 TYR S CD2   1 
ATOM   8238 C CE1   . TYR E 4 190 ? 117.599 88.728  84.995  1.00 18.56  ? 178 TYR S CE1   1 
ATOM   8239 C CE2   . TYR E 4 190 ? 119.612 87.986  83.938  1.00 18.56  ? 178 TYR S CE2   1 
ATOM   8240 C CZ    . TYR E 4 190 ? 118.630 88.936  84.104  1.00 18.56  ? 178 TYR S CZ    1 
ATOM   8241 O OH    . TYR E 4 190 ? 118.681 90.097  83.369  1.00 18.56  ? 178 TYR S OH    1 
ATOM   8242 N N     . ARG E 4 191 ? 115.155 85.105  85.577  1.00 18.04  ? 179 ARG S N     1 
ATOM   8243 C CA    . ARG E 4 191 ? 113.756 84.979  85.987  1.00 18.04  ? 179 ARG S CA    1 
ATOM   8244 C C     . ARG E 4 191 ? 112.879 84.283  84.952  1.00 18.04  ? 179 ARG S C     1 
ATOM   8245 O O     . ARG E 4 191 ? 112.371 83.186  85.202  1.00 18.04  ? 179 ARG S O     1 
ATOM   8246 C CB    . ARG E 4 191 ? 113.185 86.356  86.335  1.00 18.04  ? 179 ARG S CB    1 
ATOM   8247 C CG    . ARG E 4 191 ? 113.461 86.742  87.783  1.00 18.04  ? 179 ARG S CG    1 
ATOM   8248 C CD    . ARG E 4 191 ? 113.362 88.234  88.034  1.00 18.04  ? 179 ARG S CD    1 
ATOM   8249 N NE    . ARG E 4 191 ? 114.285 88.647  89.088  1.00 18.04  ? 179 ARG S NE    1 
ATOM   8250 C CZ    . ARG E 4 191 ? 115.371 89.389  88.906  1.00 18.04  ? 179 ARG S CZ    1 
ATOM   8251 N NH1   . ARG E 4 191 ? 115.707 89.852  87.712  1.00 18.04  ? 179 ARG S NH1   1 
ATOM   8252 N NH2   . ARG E 4 191 ? 116.143 89.673  89.950  1.00 18.04  ? 179 ARG S NH2   1 
ATOM   8253 N N     . MET E 4 192 ? 112.726 84.895  83.773  1.00 25.35  ? 180 MET S N     1 
ATOM   8254 C CA    . MET E 4 192 ? 111.887 84.338  82.707  1.00 25.35  ? 180 MET S CA    1 
ATOM   8255 C C     . MET E 4 192 ? 112.349 84.979  81.399  1.00 25.35  ? 180 MET S C     1 
ATOM   8256 O O     . MET E 4 192 ? 112.021 86.138  81.131  1.00 25.35  ? 180 MET S O     1 
ATOM   8257 C CB    . MET E 4 192 ? 110.403 84.593  82.940  1.00 25.35  ? 180 MET S CB    1 
ATOM   8258 C CG    . MET E 4 192 ? 109.808 84.040  84.230  1.00 25.35  ? 180 MET S CG    1 
ATOM   8259 S SD    . MET E 4 192 ? 109.577 82.247  84.182  1.00 25.35  ? 180 MET S SD    1 
ATOM   8260 C CE    . MET E 4 192 ? 108.187 82.054  83.058  1.00 25.35  ? 180 MET S CE    1 
ATOM   8261 N N     . SER E 4 193 ? 113.098 84.226  80.599  1.00 29.84  ? 181 SER S N     1 
ATOM   8262 C CA    . SER E 4 193 ? 113.664 84.680  79.335  1.00 29.84  ? 181 SER S CA    1 
ATOM   8263 C C     . SER E 4 193 ? 114.744 85.734  79.527  1.00 29.84  ? 181 SER S C     1 
ATOM   8264 O O     . SER E 4 193 ? 115.353 86.161  78.538  1.00 29.84  ? 181 SER S O     1 
ATOM   8265 C CB    . SER E 4 193 ? 112.597 85.253  78.391  1.00 29.84  ? 181 SER S CB    1 
ATOM   8266 O OG    . SER E 4 193 ? 112.182 86.539  78.816  1.00 29.84  ? 181 SER S OG    1 
ATOM   8267 N N     . ASN E 4 194 ? 115.010 86.170  80.759  1.00 22.97  ? 182 ASN S N     1 
ATOM   8268 C CA    . ASN E 4 194 ? 115.984 87.229  81.009  1.00 22.97  ? 182 ASN S CA    1 
ATOM   8269 C C     . ASN E 4 194 ? 117.379 86.624  80.885  1.00 22.97  ? 182 ASN S C     1 
ATOM   8270 O O     . ASN E 4 194 ? 117.975 86.132  81.845  1.00 22.97  ? 182 ASN S O     1 
ATOM   8271 C CB    . ASN E 4 194 ? 115.760 87.859  82.376  1.00 22.97  ? 182 ASN S CB    1 
ATOM   8272 C CG    . ASN E 4 194 ? 114.570 88.799  82.401  1.00 22.97  ? 182 ASN S CG    1 
ATOM   8273 O OD1   . ASN E 4 194 ? 114.370 89.593  81.481  1.00 22.97  ? 182 ASN S OD1   1 
ATOM   8274 N ND2   . ASN E 4 194 ? 113.777 88.719  83.462  1.00 22.97  ? 182 ASN S ND2   1 
ATOM   8275 N N     . LEU E 4 195 ? 117.902 86.668  79.663  1.00 25.64  ? 183 LEU S N     1 
ATOM   8276 C CA    . LEU E 4 195 ? 119.194 86.063  79.377  1.00 25.64  ? 183 LEU S CA    1 
ATOM   8277 C C     . LEU E 4 195 ? 120.285 86.700  80.227  1.00 25.64  ? 183 LEU S C     1 
ATOM   8278 O O     . LEU E 4 195 ? 120.292 87.912  80.455  1.00 25.64  ? 183 LEU S O     1 
ATOM   8279 C CB    . LEU E 4 195 ? 119.523 86.216  77.893  1.00 25.64  ? 183 LEU S CB    1 
ATOM   8280 C CG    . LEU E 4 195 ? 120.655 85.340  77.361  1.00 25.64  ? 183 LEU S CG    1 
ATOM   8281 C CD1   . LEU E 4 195 ? 120.268 83.872  77.422  1.00 25.64  ? 183 LEU S CD1   1 
ATOM   8282 C CD2   . LEU E 4 195 ? 121.010 85.748  75.944  1.00 25.64  ? 183 LEU S CD2   1 
ATOM   8283 N N     . ALA E 4 196 ? 121.211 85.870  80.698  1.00 23.73  ? 184 ALA S N     1 
ATOM   8284 C CA    . ALA E 4 196 ? 122.305 86.340  81.530  1.00 23.73  ? 184 ALA S CA    1 
ATOM   8285 C C     . ALA E 4 196 ? 123.335 87.079  80.678  1.00 23.73  ? 184 ALA S C     1 
ATOM   8286 O O     . ALA E 4 196 ? 123.171 87.262  79.469  1.00 23.73  ? 184 ALA S O     1 
ATOM   8287 C CB    . ALA E 4 196 ? 122.944 85.168  82.273  1.00 23.73  ? 184 ALA S CB    1 
ATOM   8288 N N     . SER E 4 197 ? 124.417 87.509  81.321  1.00 23.37  ? 185 SER S N     1 
ATOM   8289 C CA    . SER E 4 197 ? 125.481 88.251  80.655  1.00 23.37  ? 185 SER S CA    1 
ATOM   8290 C C     . SER E 4 197 ? 126.487 87.259  80.084  1.00 23.37  ? 185 SER S C     1 
ATOM   8291 O O     . SER E 4 197 ? 127.039 86.432  80.818  1.00 23.37  ? 185 SER S O     1 
ATOM   8292 C CB    . SER E 4 197 ? 126.153 89.215  81.630  1.00 23.37  ? 185 SER S CB    1 
ATOM   8293 O OG    . SER E 4 197 ? 127.211 89.921  81.006  1.00 23.37  ? 185 SER S OG    1 
ATOM   8294 N N     . GLY E 4 198 ? 126.724 87.339  78.779  1.00 26.18  ? 186 GLY S N     1 
ATOM   8295 C CA    . GLY E 4 198 ? 127.672 86.475  78.099  1.00 26.18  ? 186 GLY S CA    1 
ATOM   8296 C C     . GLY E 4 198 ? 127.059 85.257  77.442  1.00 26.18  ? 186 GLY S C     1 
ATOM   8297 O O     . GLY E 4 198 ? 127.797 84.461  76.843  1.00 26.18  ? 186 GLY S O     1 
ATOM   8298 N N     . VAL E 4 199 ? 125.746 85.071  77.526  1.00 27.50  ? 187 VAL S N     1 
ATOM   8299 C CA    . VAL E 4 199 ? 125.085 83.899  76.959  1.00 27.50  ? 187 VAL S CA    1 
ATOM   8300 C C     . VAL E 4 199 ? 124.605 84.250  75.555  1.00 27.50  ? 187 VAL S C     1 
ATOM   8301 O O     . VAL E 4 199 ? 124.114 85.367  75.336  1.00 27.50  ? 187 VAL S O     1 
ATOM   8302 C CB    . VAL E 4 199 ? 123.923 83.434  77.852  1.00 27.50  ? 187 VAL S CB    1 
ATOM   8303 C CG1   . VAL E 4 199 ? 123.259 82.188  77.280  1.00 27.50  ? 187 VAL S CG1   1 
ATOM   8304 C CG2   . VAL E 4 199 ? 124.413 83.177  79.268  1.00 27.50  ? 187 VAL S CG2   1 
ATOM   8305 N N     . PRO E 4 200 ? 124.725 83.351  74.576  1.00 32.54  ? 188 PRO S N     1 
ATOM   8306 C CA    . PRO E 4 200 ? 124.218 83.661  73.235  1.00 32.54  ? 188 PRO S CA    1 
ATOM   8307 C C     . PRO E 4 200 ? 122.715 83.891  73.246  1.00 32.54  ? 188 PRO S C     1 
ATOM   8308 O O     . PRO E 4 200 ? 121.977 83.305  74.040  1.00 32.54  ? 188 PRO S O     1 
ATOM   8309 C CB    . PRO E 4 200 ? 124.593 82.423  72.412  1.00 32.54  ? 188 PRO S CB    1 
ATOM   8310 C CG    . PRO E 4 200 ? 124.848 81.349  73.409  1.00 32.54  ? 188 PRO S CG    1 
ATOM   8311 C CD    . PRO E 4 200 ? 125.381 82.034  74.621  1.00 32.54  ? 188 PRO S CD    1 
ATOM   8312 N N     . ASP E 4 201 ? 122.264 84.759  72.338  1.00 34.93  ? 189 ASP S N     1 
ATOM   8313 C CA    . ASP E 4 201 ? 120.866 85.170  72.304  1.00 34.93  ? 189 ASP S CA    1 
ATOM   8314 C C     . ASP E 4 201 ? 119.919 84.048  71.900  1.00 34.93  ? 189 ASP S C     1 
ATOM   8315 O O     . ASP E 4 201 ? 118.703 84.214  72.042  1.00 34.93  ? 189 ASP S O     1 
ATOM   8316 C CB    . ASP E 4 201 ? 120.693 86.346  71.341  1.00 34.93  ? 189 ASP S CB    1 
ATOM   8317 C CG    . ASP E 4 201 ? 121.005 85.974  69.905  1.00 34.93  ? 189 ASP S CG    1 
ATOM   8318 O OD1   . ASP E 4 201 ? 121.745 84.992  69.690  1.00 34.93  ? 189 ASP S OD1   1 
ATOM   8319 O OD2   . ASP E 4 201 ? 120.508 86.664  68.989  1.00 34.93  ? 189 ASP S OD2   1 
ATOM   8320 N N     . ARG E 4 202 ? 120.431 82.922  71.399  1.00 39.08  ? 190 ARG S N     1 
ATOM   8321 C CA    . ARG E 4 202 ? 119.543 81.853  70.951  1.00 39.08  ? 190 ARG S CA    1 
ATOM   8322 C C     . ARG E 4 202 ? 118.732 81.280  72.108  1.00 39.08  ? 190 ARG S C     1 
ATOM   8323 O O     . ARG E 4 202 ? 117.538 81.000  71.955  1.00 39.08  ? 190 ARG S O     1 
ATOM   8324 C CB    . ARG E 4 202 ? 120.348 80.754  70.256  1.00 39.08  ? 190 ARG S CB    1 
ATOM   8325 C CG    . ARG E 4 202 ? 121.346 80.030  71.144  1.00 39.08  ? 190 ARG S CG    1 
ATOM   8326 C CD    . ARG E 4 202 ? 122.098 78.964  70.360  1.00 39.08  ? 190 ARG S CD    1 
ATOM   8327 N NE    . ARG E 4 202 ? 123.448 78.747  70.866  1.00 39.08  ? 190 ARG S NE    1 
ATOM   8328 C CZ    . ARG E 4 202 ? 124.514 79.439  70.488  1.00 39.08  ? 190 ARG S CZ    1 
ATOM   8329 N NH1   . ARG E 4 202 ? 124.427 80.418  69.602  1.00 39.08  ? 190 ARG S NH1   1 
ATOM   8330 N NH2   . ARG E 4 202 ? 125.700 79.140  71.012  1.00 39.08  ? 190 ARG S NH2   1 
ATOM   8331 N N     . PHE E 4 203 ? 119.358 81.097  73.269  1.00 32.60  ? 191 PHE S N     1 
ATOM   8332 C CA    . PHE E 4 203 ? 118.642 80.572  74.425  1.00 32.60  ? 191 PHE S CA    1 
ATOM   8333 C C     . PHE E 4 203 ? 117.521 81.519  74.830  1.00 32.60  ? 191 PHE S C     1 
ATOM   8334 O O     . PHE E 4 203 ? 117.714 82.736  74.901  1.00 32.60  ? 191 PHE S O     1 
ATOM   8335 C CB    . PHE E 4 203 ? 119.604 80.371  75.596  1.00 32.60  ? 191 PHE S CB    1 
ATOM   8336 C CG    . PHE E 4 203 ? 120.557 79.228  75.409  1.00 32.60  ? 191 PHE S CG    1 
ATOM   8337 C CD1   . PHE E 4 203 ? 121.657 79.354  74.580  1.00 32.60  ? 191 PHE S CD1   1 
ATOM   8338 C CD2   . PHE E 4 203 ? 120.354 78.028  76.066  1.00 32.60  ? 191 PHE S CD2   1 
ATOM   8339 C CE1   . PHE E 4 203 ? 122.536 78.304  74.410  1.00 32.60  ? 191 PHE S CE1   1 
ATOM   8340 C CE2   . PHE E 4 203 ? 121.229 76.975  75.898  1.00 32.60  ? 191 PHE S CE2   1 
ATOM   8341 C CZ    . PHE E 4 203 ? 122.321 77.114  75.069  1.00 32.60  ? 191 PHE S CZ    1 
ATOM   8342 N N     . SER E 4 204 ? 116.344 80.957  75.101  1.00 31.01  ? 192 SER S N     1 
ATOM   8343 C CA    . SER E 4 204 ? 115.203 81.730  75.567  1.00 31.01  ? 192 SER S CA    1 
ATOM   8344 C C     . SER E 4 204 ? 114.436 80.911  76.592  1.00 31.01  ? 192 SER S C     1 
ATOM   8345 O O     . SER E 4 204 ? 114.518 79.682  76.608  1.00 31.01  ? 192 SER S O     1 
ATOM   8346 C CB    . SER E 4 204 ? 114.278 82.125  74.409  1.00 31.01  ? 192 SER S CB    1 
ATOM   8347 O OG    . SER E 4 204 ? 113.001 82.511  74.885  1.00 31.01  ? 192 SER S OG    1 
ATOM   8348 N N     . GLY E 4 205 ? 113.689 81.604  77.452  1.00 29.14  ? 193 GLY S N     1 
ATOM   8349 C CA    . GLY E 4 205 ? 112.869 80.946  78.442  1.00 29.14  ? 193 GLY S CA    1 
ATOM   8350 C C     . GLY E 4 205 ? 111.446 81.468  78.395  1.00 29.14  ? 193 GLY S C     1 
ATOM   8351 O O     . GLY E 4 205 ? 111.167 82.526  77.833  1.00 29.14  ? 193 GLY S O     1 
ATOM   8352 N N     . SER E 4 206 ? 110.544 80.698  78.985  1.00 30.58  ? 194 SER S N     1 
ATOM   8353 C CA    . SER E 4 206 ? 109.142 81.097  79.076  1.00 30.58  ? 194 SER S CA    1 
ATOM   8354 C C     . SER E 4 206 ? 108.432 80.110  79.996  1.00 30.58  ? 194 SER S C     1 
ATOM   8355 O O     . SER E 4 206 ? 109.037 79.151  80.490  1.00 30.58  ? 194 SER S O     1 
ATOM   8356 C CB    . SER E 4 206 ? 108.496 81.160  77.691  1.00 30.58  ? 194 SER S CB    1 
ATOM   8357 O OG    . SER E 4 206 ? 108.622 79.923  77.012  1.00 30.58  ? 194 SER S OG    1 
ATOM   8358 N N     . GLY E 4 207 ? 107.148 80.338  80.220  1.00 32.02  ? 195 GLY S N     1 
ATOM   8359 C CA    . GLY E 4 207 ? 106.336 79.484  81.053  1.00 32.02  ? 195 GLY S CA    1 
ATOM   8360 C C     . GLY E 4 207 ? 105.235 80.283  81.707  1.00 32.02  ? 195 GLY S C     1 
ATOM   8361 O O     . GLY E 4 207 ? 105.088 81.483  81.476  1.00 32.02  ? 195 GLY S O     1 
ATOM   8362 N N     . SER E 4 208 ? 104.442 79.602  82.536  1.00 32.44  ? 196 SER S N     1 
ATOM   8363 C CA    . SER E 4 208 ? 103.330 80.265  83.218  1.00 32.44  ? 196 SER S CA    1 
ATOM   8364 C C     . SER E 4 208 ? 102.970 79.456  84.464  1.00 32.44  ? 196 SER S C     1 
ATOM   8365 O O     . SER E 4 208 ? 102.395 78.370  84.353  1.00 32.44  ? 196 SER S O     1 
ATOM   8366 C CB    . SER E 4 208 ? 102.136 80.415  82.289  1.00 32.44  ? 196 SER S CB    1 
ATOM   8367 O OG    . SER E 4 208 ? 101.734 79.160  81.768  1.00 32.44  ? 196 SER S OG    1 
ATOM   8368 N N     . GLY E 4 209 ? 103.312 79.995  85.632  1.00 29.68  ? 197 GLY S N     1 
ATOM   8369 C CA    . GLY E 4 209 ? 102.846 79.448  86.891  1.00 29.68  ? 197 GLY S CA    1 
ATOM   8370 C C     . GLY E 4 209 ? 103.523 78.161  87.310  1.00 29.68  ? 197 GLY S C     1 
ATOM   8371 O O     . GLY E 4 209 ? 104.287 78.144  88.280  1.00 29.68  ? 197 GLY S O     1 
ATOM   8372 N N     . THR E 4 210 ? 103.253 77.078  86.592  1.00 30.65  ? 198 THR S N     1 
ATOM   8373 C CA    . THR E 4 210 ? 103.767 75.760  86.950  1.00 30.65  ? 198 THR S CA    1 
ATOM   8374 C C     . THR E 4 210 ? 104.528 75.089  85.818  1.00 30.65  ? 198 THR S C     1 
ATOM   8375 O O     . THR E 4 210 ? 105.534 74.424  86.075  1.00 30.65  ? 198 THR S O     1 
ATOM   8376 C CB    . THR E 4 210 ? 102.611 74.852  87.398  1.00 30.65  ? 198 THR S CB    1 
ATOM   8377 O OG1   . THR E 4 210 ? 101.683 74.688  86.319  1.00 30.65  ? 198 THR S OG1   1 
ATOM   8378 C CG2   . THR E 4 210 ? 101.892 75.450  88.597  1.00 30.65  ? 198 THR S CG2   1 
ATOM   8379 N N     . ALA E 4 211 ? 104.080 75.248  84.577  1.00 32.67  ? 199 ALA S N     1 
ATOM   8380 C CA    . ALA E 4 211 ? 104.748 74.658  83.425  1.00 32.67  ? 199 ALA S CA    1 
ATOM   8381 C C     . ALA E 4 211 ? 105.705 75.682  82.832  1.00 32.67  ? 199 ALA S C     1 
ATOM   8382 O O     . ALA E 4 211 ? 105.294 76.804  82.507  1.00 32.67  ? 199 ALA S O     1 
ATOM   8383 C CB    . ALA E 4 211 ? 103.727 74.207  82.382  1.00 32.67  ? 199 ALA S CB    1 
ATOM   8384 N N     . PHE E 4 212 ? 106.974 75.298  82.677  1.00 28.41  ? 200 PHE S N     1 
ATOM   8385 C CA    . PHE E 4 212 ? 108.010 76.211  82.221  1.00 28.41  ? 200 PHE S CA    1 
ATOM   8386 C C     . PHE E 4 212 ? 108.871 75.524  81.174  1.00 28.41  ? 200 PHE S C     1 
ATOM   8387 O O     . PHE E 4 212 ? 109.105 74.314  81.250  1.00 28.41  ? 200 PHE S O     1 
ATOM   8388 C CB    . PHE E 4 212 ? 108.854 76.667  83.401  1.00 28.41  ? 200 PHE S CB    1 
ATOM   8389 C CG    . PHE E 4 212 ? 108.059 77.362  84.465  1.00 28.41  ? 200 PHE S CG    1 
ATOM   8390 C CD1   . PHE E 4 212 ? 107.715 78.694  84.329  1.00 28.41  ? 200 PHE S CD1   1 
ATOM   8391 C CD2   . PHE E 4 212 ? 107.610 76.668  85.576  1.00 28.41  ? 200 PHE S CD2   1 
ATOM   8392 C CE1   . PHE E 4 212 ? 106.977 79.334  85.300  1.00 28.41  ? 200 PHE S CE1   1 
ATOM   8393 C CE2   . PHE E 4 212 ? 106.875 77.305  86.552  1.00 28.41  ? 200 PHE S CE2   1 
ATOM   8394 C CZ    . PHE E 4 212 ? 106.554 78.639  86.411  1.00 28.41  ? 200 PHE S CZ    1 
ATOM   8395 N N     . THR E 4 213 ? 109.337 76.300  80.195  1.00 31.37  ? 201 THR S N     1 
ATOM   8396 C CA    . THR E 4 213 ? 110.050 75.768  79.045  1.00 31.37  ? 201 THR S CA    1 
ATOM   8397 C C     . THR E 4 213 ? 111.260 76.632  78.717  1.00 31.37  ? 201 THR S C     1 
ATOM   8398 O O     . THR E 4 213 ? 111.252 77.850  78.930  1.00 31.37  ? 201 THR S O     1 
ATOM   8399 C CB    . THR E 4 213 ? 109.133 75.679  77.816  1.00 31.37  ? 201 THR S CB    1 
ATOM   8400 O OG1   . THR E 4 213 ? 109.847 75.084  76.725  1.00 31.37  ? 201 THR S OG1   1 
ATOM   8401 C CG2   . THR E 4 213 ? 108.644 77.061  77.407  1.00 31.37  ? 201 THR S CG2   1 
ATOM   8402 N N     . LEU E 4 214 ? 112.300 75.979  78.210  1.00 29.36  ? 202 LEU S N     1 
ATOM   8403 C CA    . LEU E 4 214 ? 113.514 76.622  77.726  1.00 29.36  ? 202 LEU S CA    1 
ATOM   8404 C C     . LEU E 4 214 ? 113.715 76.217  76.271  1.00 29.36  ? 202 LEU S C     1 
ATOM   8405 O O     . LEU E 4 214 ? 113.821 75.024  75.967  1.00 29.36  ? 202 LEU S O     1 
ATOM   8406 C CB    . LEU E 4 214 ? 114.718 76.211  78.575  1.00 29.36  ? 202 LEU S CB    1 
ATOM   8407 C CG    . LEU E 4 214 ? 116.055 76.886  78.271  1.00 29.36  ? 202 LEU S CG    1 
ATOM   8408 C CD1   . LEU E 4 214 ? 116.055 78.329  78.744  1.00 29.36  ? 202 LEU S CD1   1 
ATOM   8409 C CD2   . LEU E 4 214 ? 117.188 76.112  78.913  1.00 29.36  ? 202 LEU S CD2   1 
ATOM   8410 N N     . THR E 4 215 ? 113.778 77.202  75.381  1.00 34.11  ? 203 THR S N     1 
ATOM   8411 C CA    . THR E 4 215 ? 113.871 76.970  73.946  1.00 34.11  ? 203 THR S CA    1 
ATOM   8412 C C     . THR E 4 215 ? 115.262 77.341  73.452  1.00 34.11  ? 203 THR S C     1 
ATOM   8413 O O     . THR E 4 215 ? 115.831 78.354  73.877  1.00 34.11  ? 203 THR S O     1 
ATOM   8414 C CB    . THR E 4 215 ? 112.819 77.782  73.189  1.00 34.11  ? 203 THR S CB    1 
ATOM   8415 O OG1   . THR E 4 215 ? 113.081 79.180  73.355  1.00 34.11  ? 203 THR S OG1   1 
ATOM   8416 C CG2   . THR E 4 215 ? 111.424 77.463  73.704  1.00 34.11  ? 203 THR S CG2   1 
ATOM   8417 N N     . ILE E 4 216 ? 115.808 76.515  72.565  1.00 39.32  ? 204 ILE S N     1 
ATOM   8418 C CA    . ILE E 4 216 ? 117.115 76.745  71.963  1.00 39.32  ? 204 ILE S CA    1 
ATOM   8419 C C     . ILE E 4 216 ? 116.943 76.657  70.454  1.00 39.32  ? 204 ILE S C     1 
ATOM   8420 O O     . ILE E 4 216 ? 116.553 75.609  69.925  1.00 39.32  ? 204 ILE S O     1 
ATOM   8421 C CB    . ILE E 4 216 ? 118.158 75.736  72.457  1.00 39.32  ? 204 ILE S CB    1 
ATOM   8422 C CG1   . ILE E 4 216 ? 118.315 75.837  73.973  1.00 39.32  ? 204 ILE S CG1   1 
ATOM   8423 C CG2   . ILE E 4 216 ? 119.498 75.977  71.772  1.00 39.32  ? 204 ILE S CG2   1 
ATOM   8424 C CD1   . ILE E 4 216 ? 119.010 74.656  74.579  1.00 39.32  ? 204 ILE S CD1   1 
ATOM   8425 N N     . SER E 4 217 ? 117.233 77.755  69.763  1.00 46.29  ? 205 SER S N     1 
ATOM   8426 C CA    . SER E 4 217 ? 117.216 77.785  68.309  1.00 46.29  ? 205 SER S CA    1 
ATOM   8427 C C     . SER E 4 217 ? 118.640 77.705  67.779  1.00 46.29  ? 205 SER S C     1 
ATOM   8428 O O     . SER E 4 217 ? 119.554 78.332  68.323  1.00 46.29  ? 205 SER S O     1 
ATOM   8429 C CB    . SER E 4 217 ? 116.537 79.059  67.804  1.00 46.29  ? 205 SER S CB    1 
ATOM   8430 O OG    . SER E 4 217 ? 115.176 79.101  68.196  1.00 46.29  ? 205 SER S OG    1 
ATOM   8431 N N     . ARG E 4 218 ? 118.827 76.925  66.718  1.00 49.55  ? 206 ARG S N     1 
ATOM   8432 C CA    . ARG E 4 218 ? 120.139 76.740  66.103  1.00 49.55  ? 206 ARG S CA    1 
ATOM   8433 C C     . ARG E 4 218 ? 121.136 76.181  67.121  1.00 49.55  ? 206 ARG S C     1 
ATOM   8434 O O     . ARG E 4 218 ? 122.136 76.805  67.478  1.00 49.55  ? 206 ARG S O     1 
ATOM   8435 C CB    . ARG E 4 218 ? 120.645 78.058  65.510  1.00 49.55  ? 206 ARG S CB    1 
ATOM   8436 C CG    . ARG E 4 218 ? 119.710 78.691  64.491  1.00 49.55  ? 206 ARG S CG    1 
ATOM   8437 C CD    . ARG E 4 218 ? 120.119 80.125  64.192  1.00 49.55  ? 206 ARG S CD    1 
ATOM   8438 N NE    . ARG E 4 218 ? 119.444 80.659  63.016  1.00 49.55  ? 206 ARG S NE    1 
ATOM   8439 C CZ    . ARG E 4 218 ? 119.679 81.857  62.496  1.00 49.55  ? 206 ARG S CZ    1 
ATOM   8440 N NH1   . ARG E 4 218 ? 120.571 82.678  63.025  1.00 49.55  ? 206 ARG S NH1   1 
ATOM   8441 N NH2   . ARG E 4 218 ? 119.000 82.241  61.419  1.00 49.55  ? 206 ARG S NH2   1 
ATOM   8442 N N     . LEU E 4 219 ? 120.825 74.973  67.584  1.00 47.15  ? 207 LEU S N     1 
ATOM   8443 C CA    . LEU E 4 219 ? 121.665 74.310  68.572  1.00 47.15  ? 207 LEU S CA    1 
ATOM   8444 C C     . LEU E 4 219 ? 123.069 74.097  68.021  1.00 47.15  ? 207 LEU S C     1 
ATOM   8445 O O     . LEU E 4 219 ? 123.252 73.791  66.839  1.00 47.15  ? 207 LEU S O     1 
ATOM   8446 C CB    . LEU E 4 219 ? 121.034 72.976  68.979  1.00 47.15  ? 207 LEU S CB    1 
ATOM   8447 C CG    . LEU E 4 219 ? 121.665 72.196  70.136  1.00 47.15  ? 207 LEU S CG    1 
ATOM   8448 C CD1   . LEU E 4 219 ? 120.612 71.338  70.803  1.00 47.15  ? 207 LEU S CD1   1 
ATOM   8449 C CD2   . LEU E 4 219 ? 122.806 71.309  69.657  1.00 47.15  ? 207 LEU S CD2   1 
ATOM   8450 N N     . GLU E 4 220 ? 124.064 74.261  68.887  1.00 46.41  ? 208 GLU S N     1 
ATOM   8451 C CA    . GLU E 4 220 ? 125.469 74.140  68.524  1.00 46.41  ? 208 GLU S CA    1 
ATOM   8452 C C     . GLU E 4 220 ? 126.125 73.046  69.368  1.00 46.41  ? 208 GLU S C     1 
ATOM   8453 O O     . GLU E 4 220 ? 125.515 72.482  70.280  1.00 46.41  ? 208 GLU S O     1 
ATOM   8454 C CB    . GLU E 4 220 ? 126.176 75.486  68.693  1.00 46.41  ? 208 GLU S CB    1 
ATOM   8455 C CG    . GLU E 4 220 ? 125.668 76.569  67.756  1.00 46.41  ? 208 GLU S CG    1 
ATOM   8456 C CD    . GLU E 4 220 ? 126.528 77.816  67.783  1.00 46.41  ? 208 GLU S CD    1 
ATOM   8457 O OE1   . GLU E 4 220 ? 127.606 77.783  68.412  1.00 46.41  ? 208 GLU S OE1   1 
ATOM   8458 O OE2   . GLU E 4 220 ? 126.124 78.831  67.176  1.00 46.41  ? 208 GLU S OE2   1 
ATOM   8459 N N     . ALA E 4 221 ? 127.391 72.757  69.060  1.00 47.30  ? 209 ALA S N     1 
ATOM   8460 C CA    . ALA E 4 221 ? 128.087 71.652  69.709  1.00 47.30  ? 209 ALA S CA    1 
ATOM   8461 C C     . ALA E 4 221 ? 128.359 71.922  71.183  1.00 47.30  ? 209 ALA S C     1 
ATOM   8462 O O     . ALA E 4 221 ? 128.537 70.974  71.957  1.00 47.30  ? 209 ALA S O     1 
ATOM   8463 C CB    . ALA E 4 221 ? 129.403 71.364  68.985  1.00 47.30  ? 209 ALA S CB    1 
ATOM   8464 N N     . GLU E 4 222 ? 128.400 73.188  71.591  1.00 44.35  ? 210 GLU S N     1 
ATOM   8465 C CA    . GLU E 4 222 ? 128.656 73.538  72.982  1.00 44.35  ? 210 GLU S CA    1 
ATOM   8466 C C     . GLU E 4 222 ? 127.392 73.556  73.833  1.00 44.35  ? 210 GLU S C     1 
ATOM   8467 O O     . GLU E 4 222 ? 127.479 73.846  75.031  1.00 44.35  ? 210 GLU S O     1 
ATOM   8468 C CB    . GLU E 4 222 ? 129.344 74.904  73.060  1.00 44.35  ? 210 GLU S CB    1 
ATOM   8469 C CG    . GLU E 4 222 ? 130.521 75.067  72.106  1.00 44.35  ? 210 GLU S CG    1 
ATOM   8470 C CD    . GLU E 4 222 ? 131.471 73.885  72.139  1.00 44.35  ? 210 GLU S CD    1 
ATOM   8471 O OE1   . GLU E 4 222 ? 131.818 73.430  73.249  1.00 44.35  ? 210 GLU S OE1   1 
ATOM   8472 O OE2   . GLU E 4 222 ? 131.871 73.411  71.055  1.00 44.35  ? 210 GLU S OE2   1 
ATOM   8473 N N     . ASP E 4 223 ? 126.232 73.257  73.255  1.00 40.33  ? 211 ASP S N     1 
ATOM   8474 C CA    . ASP E 4 223 ? 124.970 73.276  73.981  1.00 40.33  ? 211 ASP S CA    1 
ATOM   8475 C C     . ASP E 4 223 ? 124.592 71.917  74.558  1.00 40.33  ? 211 ASP S C     1 
ATOM   8476 O O     . ASP E 4 223 ? 123.499 71.782  75.117  1.00 40.33  ? 211 ASP S O     1 
ATOM   8477 C CB    . ASP E 4 223 ? 123.846 73.771  73.066  1.00 40.33  ? 211 ASP S CB    1 
ATOM   8478 C CG    . ASP E 4 223 ? 124.111 75.159  72.520  1.00 40.33  ? 211 ASP S CG    1 
ATOM   8479 O OD1   . ASP E 4 223 ? 125.234 75.669  72.713  1.00 40.33  ? 211 ASP S OD1   1 
ATOM   8480 O OD2   . ASP E 4 223 ? 123.197 75.742  71.900  1.00 40.33  ? 211 ASP S OD2   1 
ATOM   8481 N N     . VAL E 4 224 ? 125.457 70.915  74.437  1.00 39.47  ? 212 VAL S N     1 
ATOM   8482 C CA    . VAL E 4 224 ? 125.169 69.593  74.981  1.00 39.47  ? 212 VAL S CA    1 
ATOM   8483 C C     . VAL E 4 224 ? 125.504 69.574  76.466  1.00 39.47  ? 212 VAL S C     1 
ATOM   8484 O O     . VAL E 4 224 ? 126.516 70.130  76.909  1.00 39.47  ? 212 VAL S O     1 
ATOM   8485 C CB    . VAL E 4 224 ? 125.949 68.506  74.214  1.00 39.47  ? 212 VAL S CB    1 
ATOM   8486 C CG1   . VAL E 4 224 ? 125.706 68.635  72.719  1.00 39.47  ? 212 VAL S CG1   1 
ATOM   8487 C CG2   . VAL E 4 224 ? 127.436 68.586  74.530  1.00 39.47  ? 212 VAL S CG2   1 
ATOM   8488 N N     . GLY E 4 225 ? 124.649 68.924  77.243  1.00 35.39  ? 213 GLY S N     1 
ATOM   8489 C CA    . GLY E 4 225 ? 124.812 68.825  78.674  1.00 35.39  ? 213 GLY S CA    1 
ATOM   8490 C C     . GLY E 4 225 ? 123.474 68.615  79.346  1.00 35.39  ? 213 GLY S C     1 
ATOM   8491 O O     . GLY E 4 225 ? 122.508 68.161  78.732  1.00 35.39  ? 213 GLY S O     1 
ATOM   8492 N N     . VAL E 4 226 ? 123.421 68.962  80.630  1.00 30.31  ? 214 VAL S N     1 
ATOM   8493 C CA    . VAL E 4 226 ? 122.230 68.780  81.453  1.00 30.31  ? 214 VAL S CA    1 
ATOM   8494 C C     . VAL E 4 226 ? 121.625 70.144  81.752  1.00 30.31  ? 214 VAL S C     1 
ATOM   8495 O O     . VAL E 4 226 ? 122.319 71.051  82.225  1.00 30.31  ? 214 VAL S O     1 
ATOM   8496 C CB    . VAL E 4 226 ? 122.562 68.035  82.758  1.00 30.31  ? 214 VAL S CB    1 
ATOM   8497 C CG1   . VAL E 4 226 ? 121.284 67.629  83.474  1.00 30.31  ? 214 VAL S CG1   1 
ATOM   8498 C CG2   . VAL E 4 226 ? 123.433 66.823  82.478  1.00 30.31  ? 214 VAL S CG2   1 
ATOM   8499 N N     . TYR E 4 227 ? 120.331 70.287  81.490  1.00 30.00  ? 215 TYR S N     1 
ATOM   8500 C CA    . TYR E 4 227 ? 119.604 71.504  81.807  1.00 30.00  ? 215 TYR S CA    1 
ATOM   8501 C C     . TYR E 4 227 ? 118.894 71.345  83.143  1.00 30.00  ? 215 TYR S C     1 
ATOM   8502 O O     . TYR E 4 227 ? 118.239 70.326  83.397  1.00 30.00  ? 215 TYR S O     1 
ATOM   8503 C CB    . TYR E 4 227 ? 118.599 71.834  80.703  1.00 30.00  ? 215 TYR S CB    1 
ATOM   8504 C CG    . TYR E 4 227 ? 119.269 72.212  79.408  1.00 30.00  ? 215 TYR S CG    1 
ATOM   8505 C CD1   . TYR E 4 227 ? 119.833 71.243  78.591  1.00 30.00  ? 215 TYR S CD1   1 
ATOM   8506 C CD2   . TYR E 4 227 ? 119.365 73.537  79.015  1.00 30.00  ? 215 TYR S CD2   1 
ATOM   8507 C CE1   . TYR E 4 227 ? 120.459 71.582  77.412  1.00 30.00  ? 215 TYR S CE1   1 
ATOM   8508 C CE2   . TYR E 4 227 ? 119.992 73.886  77.838  1.00 30.00  ? 215 TYR S CE2   1 
ATOM   8509 C CZ    . TYR E 4 227 ? 120.537 72.905  77.040  1.00 30.00  ? 215 TYR S CZ    1 
ATOM   8510 O OH    . TYR E 4 227 ? 121.163 73.245  75.864  1.00 30.00  ? 215 TYR S OH    1 
ATOM   8511 N N     . TYR E 4 228 ? 119.046 72.355  83.999  1.00 24.92  ? 216 TYR S N     1 
ATOM   8512 C CA    . TYR E 4 228 ? 118.524 72.343  85.358  1.00 24.92  ? 216 TYR S CA    1 
ATOM   8513 C C     . TYR E 4 228 ? 117.624 73.551  85.554  1.00 24.92  ? 216 TYR S C     1 
ATOM   8514 O O     . TYR E 4 228 ? 117.997 74.670  85.187  1.00 24.92  ? 216 TYR S O     1 
ATOM   8515 C CB    . TYR E 4 228 ? 119.665 72.378  86.379  1.00 24.92  ? 216 TYR S CB    1 
ATOM   8516 C CG    . TYR E 4 228 ? 120.501 71.121  86.425  1.00 24.92  ? 216 TYR S CG    1 
ATOM   8517 C CD1   . TYR E 4 228 ? 119.960 69.918  86.850  1.00 24.92  ? 216 TYR S CD1   1 
ATOM   8518 C CD2   . TYR E 4 228 ? 121.831 71.139  86.034  1.00 24.92  ? 216 TYR S CD2   1 
ATOM   8519 C CE1   . TYR E 4 228 ? 120.725 68.770  86.895  1.00 24.92  ? 216 TYR S CE1   1 
ATOM   8520 C CE2   . TYR E 4 228 ? 122.602 69.996  86.073  1.00 24.92  ? 216 TYR S CE2   1 
ATOM   8521 C CZ    . TYR E 4 228 ? 122.044 68.814  86.501  1.00 24.92  ? 216 TYR S CZ    1 
ATOM   8522 O OH    . TYR E 4 228 ? 122.811 67.674  86.541  1.00 24.92  ? 216 TYR S OH    1 
ATOM   8523 N N     . CYS E 4 229 ? 116.445 73.330  86.129  1.00 21.66  ? 217 CYS S N     1 
ATOM   8524 C CA    . CYS E 4 229 ? 115.552 74.413  86.523  1.00 21.66  ? 217 CYS S CA    1 
ATOM   8525 C C     . CYS E 4 229 ? 115.421 74.406  88.040  1.00 21.66  ? 217 CYS S C     1 
ATOM   8526 O O     . CYS E 4 229 ? 115.063 73.382  88.632  1.00 21.66  ? 217 CYS S O     1 
ATOM   8527 C CB    . CYS E 4 229 ? 114.184 74.292  85.844  1.00 21.66  ? 217 CYS S CB    1 
ATOM   8528 S SG    . CYS E 4 229 ? 113.116 72.922  86.372  1.00 21.66  ? 217 CYS S SG    1 
ATOM   8529 N N     . MET E 4 230 ? 115.728 75.542  88.658  1.00 18.77  ? 218 MET S N     1 
ATOM   8530 C CA    . MET E 4 230 ? 115.633 75.741  90.095  1.00 18.77  ? 218 MET S CA    1 
ATOM   8531 C C     . MET E 4 230 ? 114.593 76.819  90.379  1.00 18.77  ? 218 MET S C     1 
ATOM   8532 O O     . MET E 4 230 ? 114.178 77.557  89.485  1.00 18.77  ? 218 MET S O     1 
ATOM   8533 C CB    . MET E 4 230 ? 116.995 76.143  90.676  1.00 18.77  ? 218 MET S CB    1 
ATOM   8534 C CG    . MET E 4 230 ? 117.106 76.001  92.186  1.00 18.77  ? 218 MET S CG    1 
ATOM   8535 S SD    . MET E 4 230 ? 118.582 76.772  92.869  1.00 18.77  ? 218 MET S SD    1 
ATOM   8536 C CE    . MET E 4 230 ? 118.168 78.496  92.683  1.00 18.77  ? 218 MET S CE    1 
ATOM   8537 N N     . GLN E 4 231 ? 114.150 76.889  91.630  1.00 18.28  ? 219 GLN S N     1 
ATOM   8538 C CA    . GLN E 4 231 ? 113.226 77.925  92.066  1.00 18.28  ? 219 GLN S CA    1 
ATOM   8539 C C     . GLN E 4 231 ? 113.816 78.680  93.248  1.00 18.28  ? 219 GLN S C     1 
ATOM   8540 O O     . GLN E 4 231 ? 114.567 78.120  94.052  1.00 18.28  ? 219 GLN S O     1 
ATOM   8541 C CB    . GLN E 4 231 ? 111.858 77.338  92.444  1.00 18.28  ? 219 GLN S CB    1 
ATOM   8542 C CG    . GLN E 4 231 ? 111.866 76.447  93.676  1.00 18.28  ? 219 GLN S CG    1 
ATOM   8543 C CD    . GLN E 4 231 ? 111.634 77.218  94.960  1.00 18.28  ? 219 GLN S CD    1 
ATOM   8544 O OE1   . GLN E 4 231 ? 110.755 78.076  95.031  1.00 18.28  ? 219 GLN S OE1   1 
ATOM   8545 N NE2   . GLN E 4 231 ? 112.420 76.912  95.986  1.00 18.28  ? 219 GLN S NE2   1 
ATOM   8546 N N     . HIS E 4 232 ? 113.472 79.966  93.338  1.00 15.31  ? 220 HIS S N     1 
ATOM   8547 C CA    . HIS E 4 232 ? 113.959 80.833  94.402  1.00 15.31  ? 220 HIS S CA    1 
ATOM   8548 C C     . HIS E 4 232 ? 112.823 81.501  95.166  1.00 15.31  ? 220 HIS S C     1 
ATOM   8549 O O     . HIS E 4 232 ? 113.087 82.364  96.010  1.00 15.31  ? 220 HIS S O     1 
ATOM   8550 C CB    . HIS E 4 232 ? 114.895 81.903  93.827  1.00 15.31  ? 220 HIS S CB    1 
ATOM   8551 C CG    . HIS E 4 232 ? 115.916 82.406  94.800  1.00 15.31  ? 220 HIS S CG    1 
ATOM   8552 N ND1   . HIS E 4 232 ? 115.644 83.394  95.721  1.00 15.31  ? 220 HIS S ND1   1 
ATOM   8553 C CD2   . HIS E 4 232 ? 117.214 82.069  94.983  1.00 15.31  ? 220 HIS S CD2   1 
ATOM   8554 C CE1   . HIS E 4 232 ? 116.727 83.636  96.437  1.00 15.31  ? 220 HIS S CE1   1 
ATOM   8555 N NE2   . HIS E 4 232 ? 117.694 82.847  96.008  1.00 15.31  ? 220 HIS S NE2   1 
ATOM   8556 N N     . LEU E 4 233 ? 111.569 81.125  94.897  1.00 18.14  ? 221 LEU S N     1 
ATOM   8557 C CA    . LEU E 4 233 ? 110.441 81.775  95.558  1.00 18.14  ? 221 LEU S CA    1 
ATOM   8558 C C     . LEU E 4 233 ? 110.505 81.591  97.067  1.00 18.14  ? 221 LEU S C     1 
ATOM   8559 O O     . LEU E 4 233 ? 110.293 82.544  97.826  1.00 18.14  ? 221 LEU S O     1 
ATOM   8560 C CB    . LEU E 4 233 ? 109.127 81.216  95.010  1.00 18.14  ? 221 LEU S CB    1 
ATOM   8561 C CG    . LEU E 4 233 ? 107.833 81.720  95.658  1.00 18.14  ? 221 LEU S CG    1 
ATOM   8562 C CD1   . LEU E 4 233 ? 107.510 83.132  95.195  1.00 18.14  ? 221 LEU S CD1   1 
ATOM   8563 C CD2   . LEU E 4 233 ? 106.675 80.777  95.369  1.00 18.14  ? 221 LEU S CD2   1 
ATOM   8564 N N     . GLU E 4 234 ? 110.790 80.374  97.521  1.00 19.50  ? 222 GLU S N     1 
ATOM   8565 C CA    . GLU E 4 234 ? 110.840 80.074  98.943  1.00 19.50  ? 222 GLU S CA    1 
ATOM   8566 C C     . GLU E 4 234 ? 112.012 79.146  99.212  1.00 19.50  ? 222 GLU S C     1 
ATOM   8567 O O     . GLU E 4 234 ? 112.428 78.381  98.339  1.00 19.50  ? 222 GLU S O     1 
ATOM   8568 C CB    . GLU E 4 234 ? 109.540 79.424  99.428  1.00 19.50  ? 222 GLU S CB    1 
ATOM   8569 C CG    . GLU E 4 234 ? 108.334 80.341  99.388  1.00 19.50  ? 222 GLU S CG    1 
ATOM   8570 C CD    . GLU E 4 234 ? 107.060 79.644  99.817  1.00 19.50  ? 222 GLU S CD    1 
ATOM   8571 O OE1   . GLU E 4 234 ? 107.093 78.412  100.017 1.00 19.50  ? 222 GLU S OE1   1 
ATOM   8572 O OE2   . GLU E 4 234 ? 106.025 80.329  99.953  1.00 19.50  ? 222 GLU S OE2   1 
ATOM   8573 N N     . TYR E 4 235 ? 112.539 79.225  100.426 1.00 15.65  ? 223 TYR S N     1 
ATOM   8574 C CA    . TYR E 4 235 ? 113.569 78.270  100.808 1.00 15.65  ? 223 TYR S CA    1 
ATOM   8575 C C     . TYR E 4 235 ? 112.931 77.042  101.456 1.00 15.65  ? 223 TYR S C     1 
ATOM   8576 O O     . TYR E 4 235 ? 111.849 77.144  102.042 1.00 15.65  ? 223 TYR S O     1 
ATOM   8577 C CB    . TYR E 4 235 ? 114.564 78.905  101.772 1.00 15.65  ? 223 TYR S CB    1 
ATOM   8578 C CG    . TYR E 4 235 ? 115.349 80.037  101.156 1.00 15.65  ? 223 TYR S CG    1 
ATOM   8579 C CD1   . TYR E 4 235 ? 114.803 81.307  101.042 1.00 15.65  ? 223 TYR S CD1   1 
ATOM   8580 C CD2   . TYR E 4 235 ? 116.636 79.833  100.680 1.00 15.65  ? 223 TYR S CD2   1 
ATOM   8581 C CE1   . TYR E 4 235 ? 115.519 82.343  100.476 1.00 15.65  ? 223 TYR S CE1   1 
ATOM   8582 C CE2   . TYR E 4 235 ? 117.358 80.862  100.112 1.00 15.65  ? 223 TYR S CE2   1 
ATOM   8583 C CZ    . TYR E 4 235 ? 116.796 82.114  100.012 1.00 15.65  ? 223 TYR S CZ    1 
ATOM   8584 O OH    . TYR E 4 235 ? 117.516 83.140  99.446  1.00 15.65  ? 223 TYR S OH    1 
ATOM   8585 N N     . PRO E 4 236 ? 113.566 75.863  101.374 1.00 20.38  ? 224 PRO S N     1 
ATOM   8586 C CA    . PRO E 4 236 ? 114.866 75.626  100.738 1.00 20.38  ? 224 PRO S CA    1 
ATOM   8587 C C     . PRO E 4 236 ? 114.797 75.630  99.214  1.00 20.38  ? 224 PRO S C     1 
ATOM   8588 O O     . PRO E 4 236 ? 113.760 75.285  98.648  1.00 20.38  ? 224 PRO S O     1 
ATOM   8589 C CB    . PRO E 4 236 ? 115.258 74.244  101.261 1.00 20.38  ? 224 PRO S CB    1 
ATOM   8590 C CG    . PRO E 4 236 ? 113.967 73.555  101.504 1.00 20.38  ? 224 PRO S CG    1 
ATOM   8591 C CD    . PRO E 4 236 ? 112.965 74.615  101.876 1.00 20.38  ? 224 PRO S CD    1 
ATOM   8592 N N     . LEU E 4 237 ? 115.891 76.021  98.565  1.00 16.82  ? 225 LEU S N     1 
ATOM   8593 C CA    . LEU E 4 237 ? 115.937 76.024  97.108  1.00 16.82  ? 225 LEU S CA    1 
ATOM   8594 C C     . LEU E 4 237 ? 115.989 74.593  96.586  1.00 16.82  ? 225 LEU S C     1 
ATOM   8595 O O     . LEU E 4 237 ? 116.777 73.774  97.068  1.00 16.82  ? 225 LEU S O     1 
ATOM   8596 C CB    . LEU E 4 237 ? 117.150 76.813  96.618  1.00 16.82  ? 225 LEU S CB    1 
ATOM   8597 C CG    . LEU E 4 237 ? 117.340 78.206  97.226  1.00 16.82  ? 225 LEU S CG    1 
ATOM   8598 C CD1   . LEU E 4 237 ? 118.659 78.812  96.772  1.00 16.82  ? 225 LEU S CD1   1 
ATOM   8599 C CD2   . LEU E 4 237 ? 116.182 79.115  96.862  1.00 16.82  ? 225 LEU S CD2   1 
ATOM   8600 N N     . THR E 4 238 ? 115.151 74.294  95.597  1.00 19.27  ? 226 THR S N     1 
ATOM   8601 C CA    . THR E 4 238 ? 115.021 72.944  95.061  1.00 19.27  ? 226 THR S CA    1 
ATOM   8602 C C     . THR E 4 238 ? 115.347 72.959  93.576  1.00 19.27  ? 226 THR S C     1 
ATOM   8603 O O     . THR E 4 238 ? 114.739 73.717  92.812  1.00 19.27  ? 226 THR S O     1 
ATOM   8604 C CB    . THR E 4 238 ? 113.609 72.395  95.294  1.00 19.27  ? 226 THR S CB    1 
ATOM   8605 O OG1   . THR E 4 238 ? 112.639 73.356  94.858  1.00 19.27  ? 226 THR S OG1   1 
ATOM   8606 C CG2   . THR E 4 238 ? 113.389 72.095  96.767  1.00 19.27  ? 226 THR S CG2   1 
ATOM   8607 N N     . PHE E 4 239 ? 116.302 72.126  93.173  1.00 19.56  ? 227 PHE S N     1 
ATOM   8608 C CA    . PHE E 4 239 ? 116.629 71.932  91.770  1.00 19.56  ? 227 PHE S CA    1 
ATOM   8609 C C     . PHE E 4 239 ? 115.760 70.829  91.175  1.00 19.56  ? 227 PHE S C     1 
ATOM   8610 O O     . PHE E 4 239 ? 114.942 70.206  91.855  1.00 19.56  ? 227 PHE S O     1 
ATOM   8611 C CB    . PHE E 4 239 ? 118.104 71.567  91.594  1.00 19.56  ? 227 PHE S CB    1 
ATOM   8612 C CG    . PHE E 4 239 ? 119.063 72.590  92.127  1.00 19.56  ? 227 PHE S CG    1 
ATOM   8613 C CD1   . PHE E 4 239 ? 119.324 72.679  93.484  1.00 19.56  ? 227 PHE S CD1   1 
ATOM   8614 C CD2   . PHE E 4 239 ? 119.729 73.447  91.266  1.00 19.56  ? 227 PHE S CD2   1 
ATOM   8615 C CE1   . PHE E 4 239 ? 120.217 73.613  93.972  1.00 19.56  ? 227 PHE S CE1   1 
ATOM   8616 C CE2   . PHE E 4 239 ? 120.625 74.381  91.750  1.00 19.56  ? 227 PHE S CE2   1 
ATOM   8617 C CZ    . PHE E 4 239 ? 120.870 74.462  93.104  1.00 19.56  ? 227 PHE S CZ    1 
ATOM   8618 N N     . GLY E 4 240 ? 115.953 70.587  89.878  1.00 25.56  ? 228 GLY S N     1 
ATOM   8619 C CA    . GLY E 4 240 ? 115.333 69.474  89.199  1.00 25.56  ? 228 GLY S CA    1 
ATOM   8620 C C     . GLY E 4 240 ? 116.295 68.304  89.043  1.00 25.56  ? 228 GLY S C     1 
ATOM   8621 O O     . GLY E 4 240 ? 117.462 68.356  89.424  1.00 25.56  ? 228 GLY S O     1 
ATOM   8622 N N     . ALA E 4 241 ? 115.770 67.222  88.465  1.00 28.87  ? 229 ALA S N     1 
ATOM   8623 C CA    . ALA E 4 241 ? 116.592 66.039  88.235  1.00 28.87  ? 229 ALA S CA    1 
ATOM   8624 C C     . ALA E 4 241 ? 117.721 66.340  87.256  1.00 28.87  ? 229 ALA S C     1 
ATOM   8625 O O     . ALA E 4 241 ? 118.875 65.956  87.482  1.00 28.87  ? 229 ALA S O     1 
ATOM   8626 C CB    . ALA E 4 241 ? 115.724 64.892  87.720  1.00 28.87  ? 229 ALA S CB    1 
ATOM   8627 N N     . GLY E 4 242 ? 117.405 67.031  86.163  1.00 30.28  ? 230 GLY S N     1 
ATOM   8628 C CA    . GLY E 4 242 ? 118.387 67.349  85.144  1.00 30.28  ? 230 GLY S CA    1 
ATOM   8629 C C     . GLY E 4 242 ? 118.074 66.681  83.823  1.00 30.28  ? 230 GLY S C     1 
ATOM   8630 O O     . GLY E 4 242 ? 118.130 65.452  83.720  1.00 30.28  ? 230 GLY S O     1 
ATOM   8631 N N     . THR E 4 243 ? 117.743 67.472  82.802  1.00 34.16  ? 231 THR S N     1 
ATOM   8632 C CA    . THR E 4 243 ? 117.367 66.940  81.497  1.00 34.16  ? 231 THR S CA    1 
ATOM   8633 C C     . THR E 4 243 ? 118.590 66.946  80.589  1.00 34.16  ? 231 THR S C     1 
ATOM   8634 O O     . THR E 4 243 ? 119.117 68.013  80.265  1.00 34.16  ? 231 THR S O     1 
ATOM   8635 C CB    . THR E 4 243 ? 116.237 67.760  80.876  1.00 34.16  ? 231 THR S CB    1 
ATOM   8636 O OG1   . THR E 4 243 ? 115.099 67.747  81.747  1.00 34.16  ? 231 THR S OG1   1 
ATOM   8637 C CG2   . THR E 4 243 ? 115.835 67.178  79.530  1.00 34.16  ? 231 THR S CG2   1 
ATOM   8638 N N     . LYS E 4 244 ? 119.040 65.762  80.184  1.00 37.01  ? 232 LYS S N     1 
ATOM   8639 C CA    . LYS E 4 244 ? 120.246 65.620  79.380  1.00 37.01  ? 232 LYS S CA    1 
ATOM   8640 C C     . LYS E 4 244 ? 119.923 65.777  77.901  1.00 37.01  ? 232 LYS S C     1 
ATOM   8641 O O     . LYS E 4 244 ? 118.833 65.412  77.450  1.00 37.01  ? 232 LYS S O     1 
ATOM   8642 C CB    . LYS E 4 244 ? 120.907 64.261  79.620  1.00 37.01  ? 232 LYS S CB    1 
ATOM   8643 C CG    . LYS E 4 244 ? 122.421 64.285  79.492  1.00 37.01  ? 232 LYS S CG    1 
ATOM   8644 C CD    . LYS E 4 244 ? 123.027 62.914  79.733  1.00 37.01  ? 232 LYS S CD    1 
ATOM   8645 C CE    . LYS E 4 244 ? 123.226 62.158  78.430  1.00 37.01  ? 232 LYS S CE    1 
ATOM   8646 N NZ    . LYS E 4 244 ? 124.025 60.917  78.622  1.00 37.01  ? 232 LYS S NZ    1 
ATOM   8647 N N     . LEU E 4 245 ? 120.874 66.329  77.153  1.00 39.71  ? 233 LEU S N     1 
ATOM   8648 C CA    . LEU E 4 245 ? 120.768 66.436  75.704  1.00 39.71  ? 233 LEU S CA    1 
ATOM   8649 C C     . LEU E 4 245 ? 121.819 65.546  75.056  1.00 39.71  ? 233 LEU S C     1 
ATOM   8650 O O     . LEU E 4 245 ? 123.007 65.643  75.379  1.00 39.71  ? 233 LEU S O     1 
ATOM   8651 C CB    . LEU E 4 245 ? 120.948 67.883  75.240  1.00 39.71  ? 233 LEU S CB    1 
ATOM   8652 C CG    . LEU E 4 245 ? 119.759 68.840  75.375  1.00 39.71  ? 233 LEU S CG    1 
ATOM   8653 C CD1   . LEU E 4 245 ? 119.995 70.081  74.530  1.00 39.71  ? 233 LEU S CD1   1 
ATOM   8654 C CD2   . LEU E 4 245 ? 118.443 68.182  74.988  1.00 39.71  ? 233 LEU S CD2   1 
ATOM   8655 N N     . GLU E 4 246 ? 121.377 64.687  74.142  1.00 46.27  ? 234 GLU S N     1 
ATOM   8656 C CA    . GLU E 4 246 ? 122.251 63.769  73.431  1.00 46.27  ? 234 GLU S CA    1 
ATOM   8657 C C     . GLU E 4 246 ? 122.493 64.270  72.014  1.00 46.27  ? 234 GLU S C     1 
ATOM   8658 O O     . GLU E 4 246 ? 121.764 65.126  71.506  1.00 46.27  ? 234 GLU S O     1 
ATOM   8659 C CB    . GLU E 4 246 ? 121.651 62.360  73.389  1.00 46.27  ? 234 GLU S CB    1 
ATOM   8660 C CG    . GLU E 4 246 ? 121.984 61.504  74.603  1.00 46.27  ? 234 GLU S CG    1 
ATOM   8661 C CD    . GLU E 4 246 ? 123.459 61.155  74.687  1.00 46.27  ? 234 GLU S CD    1 
ATOM   8662 O OE1   . GLU E 4 246 ? 124.130 61.134  73.633  1.00 46.27  ? 234 GLU S OE1   1 
ATOM   8663 O OE2   . GLU E 4 246 ? 123.948 60.900  75.807  1.00 46.27  ? 234 GLU S OE2   1 
ATOM   8664 N N     . LEU E 4 247 ? 123.527 63.727  71.382  1.00 47.95  ? 235 LEU S N     1 
ATOM   8665 C CA    . LEU E 4 247 ? 123.889 64.119  70.027  1.00 47.95  ? 235 LEU S CA    1 
ATOM   8666 C C     . LEU E 4 247 ? 124.505 62.942  69.280  1.00 47.95  ? 235 LEU S C     1 
ATOM   8667 O O     . LEU E 4 247 ? 124.207 61.784  69.574  1.00 47.95  ? 235 LEU S O     1 
ATOM   8668 C CB    . LEU E 4 247 ? 124.861 65.302  70.057  1.00 47.95  ? 235 LEU S CB    1 
ATOM   8669 C CG    . LEU E 4 247 ? 125.176 65.965  68.714  1.00 47.95  ? 235 LEU S CG    1 
ATOM   8670 C CD1   . LEU E 4 247 ? 125.408 67.454  68.904  1.00 47.95  ? 235 LEU S CD1   1 
ATOM   8671 C CD2   . LEU E 4 247 ? 126.385 65.320  68.050  1.00 47.95  ? 235 LEU S CD2   1 
HETATM 8672 C "C5'" . NEC F 5 .   ? 105.433 113.058 144.268 1.00 30.40  ? 801 NEC R "C5'" 1 
HETATM 8673 O "O5'" . NEC F 5 .   ? 105.746 113.660 145.238 1.00 30.40  ? 801 NEC R "O5'" 1 
HETATM 8674 N "N5'" . NEC F 5 .   ? 106.458 112.521 143.392 1.00 30.40  ? 801 NEC R "N5'" 1 
HETATM 8675 C C51   . NEC F 5 .   ? 107.860 112.724 143.705 1.00 30.40  ? 801 NEC R C51   1 
HETATM 8676 C C52   . NEC F 5 .   ? 108.656 112.908 142.416 1.00 30.40  ? 801 NEC R C52   1 
HETATM 8677 C "C4'" . NEC F 5 .   ? 103.981 112.851 143.952 1.00 30.40  ? 801 NEC R "C4'" 1 
HETATM 8678 O "O4'" . NEC F 5 .   ? 103.370 112.024 144.978 1.00 30.40  ? 801 NEC R "O4'" 1 
HETATM 8679 C "C3'" . NEC F 5 .   ? 103.261 114.163 143.954 1.00 30.40  ? 801 NEC R "C3'" 1 
HETATM 8680 O "O3'" . NEC F 5 .   ? 102.857 114.501 142.626 1.00 30.40  ? 801 NEC R "O3'" 1 
HETATM 8681 C "C2'" . NEC F 5 .   ? 102.065 114.006 144.811 1.00 30.40  ? 801 NEC R "C2'" 1 
HETATM 8682 O "O2'" . NEC F 5 .   ? 100.892 114.000 143.997 1.00 30.40  ? 801 NEC R "O2'" 1 
HETATM 8683 C "C1'" . NEC F 5 .   ? 102.195 112.694 145.519 1.00 30.40  ? 801 NEC R "C1'" 1 
HETATM 8684 N N9    . NEC F 5 .   ? 102.348 112.888 146.925 1.00 30.40  ? 801 NEC R N9    1 
HETATM 8685 C C8    . NEC F 5 .   ? 103.502 112.991 147.406 1.00 30.40  ? 801 NEC R C8    1 
HETATM 8686 N N7    . NEC F 5 .   ? 103.349 113.156 148.723 1.00 30.40  ? 801 NEC R N7    1 
HETATM 8687 C C5    . NEC F 5 .   ? 101.857 113.141 149.031 1.00 30.40  ? 801 NEC R C5    1 
HETATM 8688 C C6    . NEC F 5 .   ? 100.931 113.240 150.058 1.00 30.40  ? 801 NEC R C6    1 
HETATM 8689 N N6    . NEC F 5 .   ? 101.385 113.435 151.422 1.00 30.40  ? 801 NEC R N6    1 
HETATM 8690 N N1    . NEC F 5 .   ? 99.646  113.160 149.798 1.00 30.40  ? 801 NEC R N1    1 
HETATM 8691 C C2    . NEC F 5 .   ? 99.197  112.984 148.579 1.00 30.40  ? 801 NEC R C2    1 
HETATM 8692 N N3    . NEC F 5 .   ? 99.986  112.877 147.529 1.00 30.40  ? 801 NEC R N3    1 
HETATM 8693 C C4    . NEC F 5 .   ? 101.304 112.945 147.673 1.00 30.40  ? 801 NEC R C4    1 
# 
