data_8YD9
# 
_entry.id   8YD9 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8YD9         pdb_00008yd9 10.2210/pdb8yd9/pdb 
WWPDB D_1300045409 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-26 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8YD9 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        . 
_pdbx_database_related.db_id          7W5O 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              kinotk@omu.ac.jp 
_pdbx_contact_author.name_first         Takayoshi 
_pdbx_contact_author.name_last          Kinoshita 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2850-5409 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hasegawa, S.'  1 0009-0004-4952-0434 
'Kinoshita, T.' 2 0000-0003-2850-5409 
# 
loop_
_citation.abstract 
_citation.abstract_id_CAS 
_citation.book_id_ISBN 
_citation.book_publisher 
_citation.book_publisher_city 
_citation.book_title 
_citation.coordinate_linkage 
_citation.country 
_citation.database_id_Medline 
_citation.details 
_citation.id 
_citation.journal_abbrev 
_citation.journal_id_ASTM 
_citation.journal_id_CSD 
_citation.journal_id_ISSN 
_citation.journal_full 
_citation.journal_issue 
_citation.journal_volume 
_citation.language 
_citation.page_first 
_citation.page_last 
_citation.title 
_citation.year 
_citation.database_id_CSD 
_citation.pdbx_database_id_DOI 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_patent 
_citation.unpublished_flag 
? ? ? ? ? ? ? ?  ? ? primary 'To Be Published'            ?      0353 ?         ? ? ?   ? ?  ?  
'Identification of a novel target site for ATP-independent p38 alpha inhibitors' ?    ? ?                          ?        ? ? 
? ? ? ? ? ? ? US ? ? 1       'Biochem Biophys Res Commun' BBRCA9 0146 1090-2104 ? ? 593 ? 73 78 
'Identification of a novel target site for ATP-independent ERK2 inhibitors.'     2022 ? 10.1016/j.bbrc.2022.01.035 35063772 ? ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kinoshita, T.' 1 0000-0003-2850-5409 
primary 'Hasegawa, S.'  2 0009-0004-4952-0434 
1       'Yoshida, M.'   3 ?                   
1       'Nagao, H.'     4 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Mitogen-activated protein kinase 14' 41343.195 1   2.7.11.24 ? ? ? 
2 non-polymer syn 
;13-[4-({Imidazo[1,2-a]pyridin-2-yl}methoxy)phenyl]-4,8-dioxa-12,14,16,18-tetraazatetracyclo[9.7.0.0^{3,9}.0^{12,17}]octadeca-1(11),2,9,15,17-pentaen-15-amine
;
481.506   1   ?         ? ? ? 
3 non-polymer syn GLYCEROL 92.094    5   ?         ? ? ? 
4 water       nat water 18.015    401 ?         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;MAP kinase 14,MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSAID-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKH
ENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE
DCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVA
DPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKH
ENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE
DCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVA
DPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;13-[4-({Imidazo[1,2-a]pyridin-2-yl}methoxy)phenyl]-4,8-dioxa-12,14,16,18-tetraazatetracyclo[9.7.0.0^{3,9}.0^{12,17}]octadeca-1(11),2,9,15,17-pentaen-15-amine
;
6GI 
3 GLYCEROL GOL 
4 water HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   GLN n 
1 4   GLU n 
1 5   ARG n 
1 6   PRO n 
1 7   THR n 
1 8   PHE n 
1 9   TYR n 
1 10  ARG n 
1 11  GLN n 
1 12  GLU n 
1 13  LEU n 
1 14  ASN n 
1 15  LYS n 
1 16  THR n 
1 17  ILE n 
1 18  TRP n 
1 19  GLU n 
1 20  VAL n 
1 21  PRO n 
1 22  GLU n 
1 23  ARG n 
1 24  TYR n 
1 25  GLN n 
1 26  ASN n 
1 27  LEU n 
1 28  SER n 
1 29  PRO n 
1 30  VAL n 
1 31  GLY n 
1 32  SER n 
1 33  GLY n 
1 34  ALA n 
1 35  TYR n 
1 36  GLY n 
1 37  SER n 
1 38  VAL n 
1 39  CYS n 
1 40  ALA n 
1 41  ALA n 
1 42  PHE n 
1 43  ASP n 
1 44  THR n 
1 45  LYS n 
1 46  THR n 
1 47  GLY n 
1 48  LEU n 
1 49  ARG n 
1 50  VAL n 
1 51  ALA n 
1 52  VAL n 
1 53  LYS n 
1 54  LYS n 
1 55  LEU n 
1 56  SER n 
1 57  ARG n 
1 58  PRO n 
1 59  PHE n 
1 60  GLN n 
1 61  SER n 
1 62  ILE n 
1 63  ILE n 
1 64  HIS n 
1 65  ALA n 
1 66  LYS n 
1 67  ARG n 
1 68  THR n 
1 69  TYR n 
1 70  ARG n 
1 71  GLU n 
1 72  LEU n 
1 73  ARG n 
1 74  LEU n 
1 75  LEU n 
1 76  LYS n 
1 77  HIS n 
1 78  MET n 
1 79  LYS n 
1 80  HIS n 
1 81  GLU n 
1 82  ASN n 
1 83  VAL n 
1 84  ILE n 
1 85  GLY n 
1 86  LEU n 
1 87  LEU n 
1 88  ASP n 
1 89  VAL n 
1 90  PHE n 
1 91  THR n 
1 92  PRO n 
1 93  ALA n 
1 94  ARG n 
1 95  SER n 
1 96  LEU n 
1 97  GLU n 
1 98  GLU n 
1 99  PHE n 
1 100 ASN n 
1 101 ASP n 
1 102 VAL n 
1 103 TYR n 
1 104 LEU n 
1 105 VAL n 
1 106 THR n 
1 107 HIS n 
1 108 LEU n 
1 109 MET n 
1 110 GLY n 
1 111 ALA n 
1 112 ASP n 
1 113 LEU n 
1 114 ASN n 
1 115 ASN n 
1 116 ILE n 
1 117 VAL n 
1 118 LYS n 
1 119 CYS n 
1 120 GLN n 
1 121 LYS n 
1 122 LEU n 
1 123 THR n 
1 124 ASP n 
1 125 ASP n 
1 126 HIS n 
1 127 VAL n 
1 128 GLN n 
1 129 PHE n 
1 130 LEU n 
1 131 ILE n 
1 132 TYR n 
1 133 GLN n 
1 134 ILE n 
1 135 LEU n 
1 136 ARG n 
1 137 GLY n 
1 138 LEU n 
1 139 LYS n 
1 140 TYR n 
1 141 ILE n 
1 142 HIS n 
1 143 SER n 
1 144 ALA n 
1 145 ASP n 
1 146 ILE n 
1 147 ILE n 
1 148 HIS n 
1 149 ARG n 
1 150 ASP n 
1 151 LEU n 
1 152 LYS n 
1 153 PRO n 
1 154 SER n 
1 155 ASN n 
1 156 LEU n 
1 157 ALA n 
1 158 VAL n 
1 159 ASN n 
1 160 GLU n 
1 161 ASP n 
1 162 CYS n 
1 163 GLU n 
1 164 LEU n 
1 165 LYS n 
1 166 ILE n 
1 167 LEU n 
1 168 ASP n 
1 169 PHE n 
1 170 GLY n 
1 171 LEU n 
1 172 ALA n 
1 173 ARG n 
1 174 HIS n 
1 175 THR n 
1 176 ASP n 
1 177 ASP n 
1 178 GLU n 
1 179 MET n 
1 180 THR n 
1 181 GLY n 
1 182 TYR n 
1 183 VAL n 
1 184 ALA n 
1 185 THR n 
1 186 ARG n 
1 187 TRP n 
1 188 TYR n 
1 189 ARG n 
1 190 ALA n 
1 191 PRO n 
1 192 GLU n 
1 193 ILE n 
1 194 MET n 
1 195 LEU n 
1 196 ASN n 
1 197 TRP n 
1 198 MET n 
1 199 HIS n 
1 200 TYR n 
1 201 ASN n 
1 202 GLN n 
1 203 THR n 
1 204 VAL n 
1 205 ASP n 
1 206 ILE n 
1 207 TRP n 
1 208 SER n 
1 209 VAL n 
1 210 GLY n 
1 211 CYS n 
1 212 ILE n 
1 213 MET n 
1 214 ALA n 
1 215 GLU n 
1 216 LEU n 
1 217 LEU n 
1 218 THR n 
1 219 GLY n 
1 220 ARG n 
1 221 THR n 
1 222 LEU n 
1 223 PHE n 
1 224 PRO n 
1 225 GLY n 
1 226 THR n 
1 227 ASP n 
1 228 HIS n 
1 229 ILE n 
1 230 ASP n 
1 231 GLN n 
1 232 LEU n 
1 233 LYS n 
1 234 LEU n 
1 235 ILE n 
1 236 LEU n 
1 237 ARG n 
1 238 LEU n 
1 239 VAL n 
1 240 GLY n 
1 241 THR n 
1 242 PRO n 
1 243 GLY n 
1 244 ALA n 
1 245 GLU n 
1 246 LEU n 
1 247 LEU n 
1 248 LYS n 
1 249 LYS n 
1 250 ILE n 
1 251 SER n 
1 252 SER n 
1 253 GLU n 
1 254 SER n 
1 255 ALA n 
1 256 ARG n 
1 257 ASN n 
1 258 TYR n 
1 259 ILE n 
1 260 GLN n 
1 261 SER n 
1 262 LEU n 
1 263 THR n 
1 264 GLN n 
1 265 MET n 
1 266 PRO n 
1 267 LYS n 
1 268 MET n 
1 269 ASN n 
1 270 PHE n 
1 271 ALA n 
1 272 ASN n 
1 273 VAL n 
1 274 PHE n 
1 275 ILE n 
1 276 GLY n 
1 277 ALA n 
1 278 ASN n 
1 279 PRO n 
1 280 LEU n 
1 281 ALA n 
1 282 VAL n 
1 283 ASP n 
1 284 LEU n 
1 285 LEU n 
1 286 GLU n 
1 287 LYS n 
1 288 MET n 
1 289 LEU n 
1 290 VAL n 
1 291 LEU n 
1 292 ASP n 
1 293 SER n 
1 294 ASP n 
1 295 LYS n 
1 296 ARG n 
1 297 ILE n 
1 298 THR n 
1 299 ALA n 
1 300 ALA n 
1 301 GLN n 
1 302 ALA n 
1 303 LEU n 
1 304 ALA n 
1 305 HIS n 
1 306 ALA n 
1 307 TYR n 
1 308 PHE n 
1 309 ALA n 
1 310 GLN n 
1 311 TYR n 
1 312 HIS n 
1 313 ASP n 
1 314 PRO n 
1 315 ASP n 
1 316 ASP n 
1 317 GLU n 
1 318 PRO n 
1 319 VAL n 
1 320 ALA n 
1 321 ASP n 
1 322 PRO n 
1 323 TYR n 
1 324 ASP n 
1 325 GLN n 
1 326 SER n 
1 327 PHE n 
1 328 GLU n 
1 329 SER n 
1 330 ARG n 
1 331 ASP n 
1 332 LEU n 
1 333 LEU n 
1 334 ILE n 
1 335 ASP n 
1 336 GLU n 
1 337 TRP n 
1 338 LYS n 
1 339 SER n 
1 340 LEU n 
1 341 THR n 
1 342 TYR n 
1 343 ASP n 
1 344 GLU n 
1 345 VAL n 
1 346 ILE n 
1 347 SER n 
1 348 PHE n 
1 349 VAL n 
1 350 PRO n 
1 351 PRO n 
1 352 PRO n 
1 353 LEU n 
1 354 ASP n 
1 355 GLN n 
1 356 GLU n 
1 357 GLU n 
1 358 MET n 
1 359 GLU n 
1 360 SER n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   360 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     511693 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
6GI non-polymer         . 
;13-[4-({Imidazo[1,2-a]pyridin-2-yl}methoxy)phenyl]-4,8-dioxa-12,14,16,18-tetraazatetracyclo[9.7.0.0^{3,9}.0^{12,17}]octadeca-1(11),2,9,15,17-pentaen-15-amine
;
?                               'C26 H23 N7 O3'  481.506 
ALA 'L-peptide linking' y ALANINE ?                               'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE ?                               'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                               'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                               'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE ?                               'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                               'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                               'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE ?                               'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE ?                               'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER ?                               'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE ?                               'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE ?                               'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE ?                               'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE ?                               'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE ?                               'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE ?                               'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE ?                               'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE ?                               'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                               'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE ?                               'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE ?                               'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   SER 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   GLU 4   4   4   GLU GLU A . n 
A 1 5   ARG 5   5   5   ARG ARG A . n 
A 1 6   PRO 6   6   6   PRO PRO A . n 
A 1 7   THR 7   7   7   THR THR A . n 
A 1 8   PHE 8   8   8   PHE PHE A . n 
A 1 9   TYR 9   9   9   TYR TYR A . n 
A 1 10  ARG 10  10  10  ARG ARG A . n 
A 1 11  GLN 11  11  11  GLN GLN A . n 
A 1 12  GLU 12  12  12  GLU GLU A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  ASN 14  14  14  ASN ASN A . n 
A 1 15  LYS 15  15  15  LYS LYS A . n 
A 1 16  THR 16  16  16  THR THR A . n 
A 1 17  ILE 17  17  17  ILE ILE A . n 
A 1 18  TRP 18  18  18  TRP TRP A . n 
A 1 19  GLU 19  19  19  GLU GLU A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  PRO 21  21  21  PRO PRO A . n 
A 1 22  GLU 22  22  22  GLU GLU A . n 
A 1 23  ARG 23  23  23  ARG ARG A . n 
A 1 24  TYR 24  24  24  TYR TYR A . n 
A 1 25  GLN 25  25  25  GLN GLN A . n 
A 1 26  ASN 26  26  26  ASN ASN A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  SER 28  28  28  SER SER A . n 
A 1 29  PRO 29  29  29  PRO PRO A . n 
A 1 30  VAL 30  30  30  VAL VAL A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  SER 32  32  32  SER SER A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  ALA 34  34  34  ALA ALA A . n 
A 1 35  TYR 35  35  35  TYR TYR A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  SER 37  37  37  SER SER A . n 
A 1 38  VAL 38  38  38  VAL VAL A . n 
A 1 39  CYS 39  39  39  CYS CYS A . n 
A 1 40  ALA 40  40  40  ALA ALA A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  PHE 42  42  42  PHE PHE A . n 
A 1 43  ASP 43  43  43  ASP ASP A . n 
A 1 44  THR 44  44  44  THR THR A . n 
A 1 45  LYS 45  45  45  LYS LYS A . n 
A 1 46  THR 46  46  46  THR THR A . n 
A 1 47  GLY 47  47  47  GLY GLY A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  ARG 49  49  49  ARG ARG A . n 
A 1 50  VAL 50  50  50  VAL VAL A . n 
A 1 51  ALA 51  51  51  ALA ALA A . n 
A 1 52  VAL 52  52  52  VAL VAL A . n 
A 1 53  LYS 53  53  53  LYS LYS A . n 
A 1 54  LYS 54  54  54  LYS LYS A . n 
A 1 55  LEU 55  55  55  LEU LEU A . n 
A 1 56  SER 56  56  56  SER SER A . n 
A 1 57  ARG 57  57  57  ARG ARG A . n 
A 1 58  PRO 58  58  58  PRO PRO A . n 
A 1 59  PHE 59  59  59  PHE PHE A . n 
A 1 60  GLN 60  60  60  GLN GLN A . n 
A 1 61  SER 61  61  61  SER SER A . n 
A 1 62  ILE 62  62  62  ILE ILE A . n 
A 1 63  ILE 63  63  63  ILE ILE A . n 
A 1 64  HIS 64  64  64  HIS HIS A . n 
A 1 65  ALA 65  65  65  ALA ALA A . n 
A 1 66  LYS 66  66  66  LYS LYS A . n 
A 1 67  ARG 67  67  67  ARG ARG A . n 
A 1 68  THR 68  68  68  THR THR A . n 
A 1 69  TYR 69  69  69  TYR TYR A . n 
A 1 70  ARG 70  70  70  ARG ARG A . n 
A 1 71  GLU 71  71  71  GLU GLU A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  LEU 75  75  75  LEU LEU A . n 
A 1 76  LYS 76  76  76  LYS LYS A . n 
A 1 77  HIS 77  77  77  HIS HIS A . n 
A 1 78  MET 78  78  78  MET MET A . n 
A 1 79  LYS 79  79  79  LYS LYS A . n 
A 1 80  HIS 80  80  80  HIS HIS A . n 
A 1 81  GLU 81  81  81  GLU GLU A . n 
A 1 82  ASN 82  82  82  ASN ASN A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  ILE 84  84  84  ILE ILE A . n 
A 1 85  GLY 85  85  85  GLY GLY A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  ASP 88  88  88  ASP ASP A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  PHE 90  90  90  PHE PHE A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  PRO 92  92  92  PRO PRO A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  ARG 94  94  94  ARG ARG A . n 
A 1 95  SER 95  95  95  SER SER A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  GLU 97  97  97  GLU GLU A . n 
A 1 98  GLU 98  98  98  GLU GLU A . n 
A 1 99  PHE 99  99  99  PHE PHE A . n 
A 1 100 ASN 100 100 100 ASN ASN A . n 
A 1 101 ASP 101 101 101 ASP ASP A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 TYR 103 103 103 TYR TYR A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 VAL 105 105 105 VAL VAL A . n 
A 1 106 THR 106 106 106 THR THR A . n 
A 1 107 HIS 107 107 107 HIS HIS A . n 
A 1 108 LEU 108 108 108 LEU LEU A . n 
A 1 109 MET 109 109 109 MET MET A . n 
A 1 110 GLY 110 110 110 GLY GLY A . n 
A 1 111 ALA 111 111 111 ALA ALA A . n 
A 1 112 ASP 112 112 112 ASP ASP A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 ASN 114 114 114 ASN ASN A . n 
A 1 115 ASN 115 115 115 ASN ASN A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 VAL 117 117 117 VAL VAL A . n 
A 1 118 LYS 118 118 118 LYS LYS A . n 
A 1 119 CYS 119 119 119 CYS CYS A . n 
A 1 120 GLN 120 120 120 GLN GLN A . n 
A 1 121 LYS 121 121 121 LYS LYS A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 THR 123 123 123 THR THR A . n 
A 1 124 ASP 124 124 124 ASP ASP A . n 
A 1 125 ASP 125 125 125 ASP ASP A . n 
A 1 126 HIS 126 126 126 HIS HIS A . n 
A 1 127 VAL 127 127 127 VAL VAL A . n 
A 1 128 GLN 128 128 128 GLN GLN A . n 
A 1 129 PHE 129 129 129 PHE PHE A . n 
A 1 130 LEU 130 130 130 LEU LEU A . n 
A 1 131 ILE 131 131 131 ILE ILE A . n 
A 1 132 TYR 132 132 132 TYR TYR A . n 
A 1 133 GLN 133 133 133 GLN GLN A . n 
A 1 134 ILE 134 134 134 ILE ILE A . n 
A 1 135 LEU 135 135 135 LEU LEU A . n 
A 1 136 ARG 136 136 136 ARG ARG A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 LEU 138 138 138 LEU LEU A . n 
A 1 139 LYS 139 139 139 LYS LYS A . n 
A 1 140 TYR 140 140 140 TYR TYR A . n 
A 1 141 ILE 141 141 141 ILE ILE A . n 
A 1 142 HIS 142 142 142 HIS HIS A . n 
A 1 143 SER 143 143 143 SER SER A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 ASP 145 145 145 ASP ASP A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 ILE 147 147 147 ILE ILE A . n 
A 1 148 HIS 148 148 148 HIS HIS A . n 
A 1 149 ARG 149 149 149 ARG ARG A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 LYS 152 152 152 LYS LYS A . n 
A 1 153 PRO 153 153 153 PRO PRO A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 ASN 155 155 155 ASN ASN A . n 
A 1 156 LEU 156 156 156 LEU LEU A . n 
A 1 157 ALA 157 157 157 ALA ALA A . n 
A 1 158 VAL 158 158 158 VAL VAL A . n 
A 1 159 ASN 159 159 159 ASN ASN A . n 
A 1 160 GLU 160 160 160 GLU GLU A . n 
A 1 161 ASP 161 161 161 ASP ASP A . n 
A 1 162 CYS 162 162 162 CYS CYS A . n 
A 1 163 GLU 163 163 163 GLU GLU A . n 
A 1 164 LEU 164 164 164 LEU LEU A . n 
A 1 165 LYS 165 165 165 LYS LYS A . n 
A 1 166 ILE 166 166 166 ILE ILE A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 ASP 168 168 168 ASP ASP A . n 
A 1 169 PHE 169 169 169 PHE PHE A . n 
A 1 170 GLY 170 170 170 GLY GLY A . n 
A 1 171 LEU 171 171 171 LEU LEU A . n 
A 1 172 ALA 172 172 172 ALA ALA A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 HIS 174 174 174 HIS HIS A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 ASP 176 176 176 ASP ASP A . n 
A 1 177 ASP 177 177 177 ASP ASP A . n 
A 1 178 GLU 178 178 178 GLU GLU A . n 
A 1 179 MET 179 179 179 MET MET A . n 
A 1 180 THR 180 180 180 THR THR A . n 
A 1 181 GLY 181 181 181 GLY GLY A . n 
A 1 182 TYR 182 182 182 TYR TYR A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 ALA 184 184 184 ALA ALA A . n 
A 1 185 THR 185 185 185 THR THR A . n 
A 1 186 ARG 186 186 186 ARG ARG A . n 
A 1 187 TRP 187 187 187 TRP TRP A . n 
A 1 188 TYR 188 188 188 TYR TYR A . n 
A 1 189 ARG 189 189 189 ARG ARG A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 PRO 191 191 191 PRO PRO A . n 
A 1 192 GLU 192 192 192 GLU GLU A . n 
A 1 193 ILE 193 193 193 ILE ILE A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 LEU 195 195 195 LEU LEU A . n 
A 1 196 ASN 196 196 196 ASN ASN A . n 
A 1 197 TRP 197 197 197 TRP TRP A . n 
A 1 198 MET 198 198 198 MET MET A . n 
A 1 199 HIS 199 199 199 HIS HIS A . n 
A 1 200 TYR 200 200 200 TYR TYR A . n 
A 1 201 ASN 201 201 201 ASN ASN A . n 
A 1 202 GLN 202 202 202 GLN GLN A . n 
A 1 203 THR 203 203 203 THR THR A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 ASP 205 205 205 ASP ASP A . n 
A 1 206 ILE 206 206 206 ILE ILE A . n 
A 1 207 TRP 207 207 207 TRP TRP A . n 
A 1 208 SER 208 208 208 SER SER A . n 
A 1 209 VAL 209 209 209 VAL VAL A . n 
A 1 210 GLY 210 210 210 GLY GLY A . n 
A 1 211 CYS 211 211 211 CYS CYS A . n 
A 1 212 ILE 212 212 212 ILE ILE A . n 
A 1 213 MET 213 213 213 MET MET A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 GLU 215 215 215 GLU GLU A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 LEU 217 217 217 LEU LEU A . n 
A 1 218 THR 218 218 218 THR THR A . n 
A 1 219 GLY 219 219 219 GLY GLY A . n 
A 1 220 ARG 220 220 220 ARG ARG A . n 
A 1 221 THR 221 221 221 THR THR A . n 
A 1 222 LEU 222 222 222 LEU LEU A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 PRO 224 224 224 PRO PRO A . n 
A 1 225 GLY 225 225 225 GLY GLY A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 ASP 227 227 227 ASP ASP A . n 
A 1 228 HIS 228 228 228 HIS HIS A . n 
A 1 229 ILE 229 229 229 ILE ILE A . n 
A 1 230 ASP 230 230 230 ASP ASP A . n 
A 1 231 GLN 231 231 231 GLN GLN A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 ILE 235 235 235 ILE ILE A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 ARG 237 237 237 ARG ARG A . n 
A 1 238 LEU 238 238 238 LEU LEU A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 GLY 240 240 240 GLY GLY A . n 
A 1 241 THR 241 241 241 THR THR A . n 
A 1 242 PRO 242 242 242 PRO PRO A . n 
A 1 243 GLY 243 243 243 GLY GLY A . n 
A 1 244 ALA 244 244 244 ALA ALA A . n 
A 1 245 GLU 245 245 245 GLU GLU A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 LYS 249 249 249 LYS LYS A . n 
A 1 250 ILE 250 250 250 ILE ILE A . n 
A 1 251 SER 251 251 251 SER SER A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 GLU 253 253 253 GLU GLU A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 ARG 256 256 256 ARG ARG A . n 
A 1 257 ASN 257 257 257 ASN ASN A . n 
A 1 258 TYR 258 258 258 TYR TYR A . n 
A 1 259 ILE 259 259 259 ILE ILE A . n 
A 1 260 GLN 260 260 260 GLN GLN A . n 
A 1 261 SER 261 261 261 SER SER A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 THR 263 263 263 THR THR A . n 
A 1 264 GLN 264 264 264 GLN GLN A . n 
A 1 265 MET 265 265 265 MET MET A . n 
A 1 266 PRO 266 266 266 PRO PRO A . n 
A 1 267 LYS 267 267 267 LYS LYS A . n 
A 1 268 MET 268 268 268 MET MET A . n 
A 1 269 ASN 269 269 269 ASN ASN A . n 
A 1 270 PHE 270 270 270 PHE PHE A . n 
A 1 271 ALA 271 271 271 ALA ALA A . n 
A 1 272 ASN 272 272 272 ASN ASN A . n 
A 1 273 VAL 273 273 273 VAL VAL A . n 
A 1 274 PHE 274 274 274 PHE PHE A . n 
A 1 275 ILE 275 275 275 ILE ILE A . n 
A 1 276 GLY 276 276 276 GLY GLY A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 ASN 278 278 278 ASN ASN A . n 
A 1 279 PRO 279 279 279 PRO PRO A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 ALA 281 281 281 ALA ALA A . n 
A 1 282 VAL 282 282 282 VAL VAL A . n 
A 1 283 ASP 283 283 283 ASP ASP A . n 
A 1 284 LEU 284 284 284 LEU LEU A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 GLU 286 286 286 GLU GLU A . n 
A 1 287 LYS 287 287 287 LYS LYS A . n 
A 1 288 MET 288 288 288 MET MET A . n 
A 1 289 LEU 289 289 289 LEU LEU A . n 
A 1 290 VAL 290 290 290 VAL VAL A . n 
A 1 291 LEU 291 291 291 LEU LEU A . n 
A 1 292 ASP 292 292 292 ASP ASP A . n 
A 1 293 SER 293 293 293 SER SER A . n 
A 1 294 ASP 294 294 294 ASP ASP A . n 
A 1 295 LYS 295 295 295 LYS LYS A . n 
A 1 296 ARG 296 296 296 ARG ARG A . n 
A 1 297 ILE 297 297 297 ILE ILE A . n 
A 1 298 THR 298 298 298 THR THR A . n 
A 1 299 ALA 299 299 299 ALA ALA A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 GLN 301 301 301 GLN GLN A . n 
A 1 302 ALA 302 302 302 ALA ALA A . n 
A 1 303 LEU 303 303 303 LEU LEU A . n 
A 1 304 ALA 304 304 304 ALA ALA A . n 
A 1 305 HIS 305 305 305 HIS HIS A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 TYR 307 307 307 TYR TYR A . n 
A 1 308 PHE 308 308 308 PHE PHE A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 GLN 310 310 310 GLN GLN A . n 
A 1 311 TYR 311 311 311 TYR TYR A . n 
A 1 312 HIS 312 312 312 HIS HIS A . n 
A 1 313 ASP 313 313 313 ASP ASP A . n 
A 1 314 PRO 314 314 314 PRO PRO A . n 
A 1 315 ASP 315 315 315 ASP ASP A . n 
A 1 316 ASP 316 316 316 ASP ASP A . n 
A 1 317 GLU 317 317 317 GLU GLU A . n 
A 1 318 PRO 318 318 318 PRO PRO A . n 
A 1 319 VAL 319 319 319 VAL VAL A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 ASP 321 321 321 ASP ASP A . n 
A 1 322 PRO 322 322 322 PRO PRO A . n 
A 1 323 TYR 323 323 323 TYR TYR A . n 
A 1 324 ASP 324 324 324 ASP ASP A . n 
A 1 325 GLN 325 325 325 GLN GLN A . n 
A 1 326 SER 326 326 326 SER SER A . n 
A 1 327 PHE 327 327 327 PHE PHE A . n 
A 1 328 GLU 328 328 328 GLU GLU A . n 
A 1 329 SER 329 329 329 SER SER A . n 
A 1 330 ARG 330 330 330 ARG ARG A . n 
A 1 331 ASP 331 331 331 ASP ASP A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 LEU 333 333 333 LEU LEU A . n 
A 1 334 ILE 334 334 334 ILE ILE A . n 
A 1 335 ASP 335 335 335 ASP ASP A . n 
A 1 336 GLU 336 336 336 GLU GLU A . n 
A 1 337 TRP 337 337 337 TRP TRP A . n 
A 1 338 LYS 338 338 338 LYS LYS A . n 
A 1 339 SER 339 339 339 SER SER A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 THR 341 341 341 THR THR A . n 
A 1 342 TYR 342 342 342 TYR TYR A . n 
A 1 343 ASP 343 343 343 ASP ASP A . n 
A 1 344 GLU 344 344 344 GLU GLU A . n 
A 1 345 VAL 345 345 345 VAL VAL A . n 
A 1 346 ILE 346 346 346 ILE ILE A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 PHE 348 348 348 PHE PHE A . n 
A 1 349 VAL 349 349 349 VAL VAL A . n 
A 1 350 PRO 350 350 350 PRO PRO A . n 
A 1 351 PRO 351 351 351 PRO PRO A . n 
A 1 352 PRO 352 352 352 PRO PRO A . n 
A 1 353 LEU 353 353 353 LEU LEU A . n 
A 1 354 ASP 354 354 ?   ?   ?   A . n 
A 1 355 GLN 355 355 ?   ?   ?   A . n 
A 1 356 GLU 356 356 ?   ?   ?   A . n 
A 1 357 GLU 357 357 ?   ?   ?   A . n 
A 1 358 MET 358 358 ?   ?   ?   A . n 
A 1 359 GLU 359 359 ?   ?   ?   A . n 
A 1 360 SER 360 360 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        6GI 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   6GI 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 6GI 1   401 401 6GI HIT A . 
C 3 GOL 1   402 402 GOL GOL A . 
D 3 GOL 1   403 403 GOL GOL A . 
E 3 GOL 1   404 405 GOL GOL A . 
F 3 GOL 1   405 406 GOL GOL A . 
G 3 GOL 1   406 407 GOL GOL A . 
H 4 HOH 1   501 404 HOH HOH A . 
H 4 HOH 2   502 306 HOH HOH A . 
H 4 HOH 3   503 269 HOH HOH A . 
H 4 HOH 4   504 112 HOH HOH A . 
H 4 HOH 5   505 341 HOH HOH A . 
H 4 HOH 6   506 275 HOH HOH A . 
H 4 HOH 7   507 310 HOH HOH A . 
H 4 HOH 8   508 153 HOH HOH A . 
H 4 HOH 9   509 172 HOH HOH A . 
H 4 HOH 10  510 271 HOH HOH A . 
H 4 HOH 11  511 289 HOH HOH A . 
H 4 HOH 12  512 322 HOH HOH A . 
H 4 HOH 13  513 292 HOH HOH A . 
H 4 HOH 14  514 110 HOH HOH A . 
H 4 HOH 15  515 51  HOH HOH A . 
H 4 HOH 16  516 123 HOH HOH A . 
H 4 HOH 17  517 164 HOH HOH A . 
H 4 HOH 18  518 328 HOH HOH A . 
H 4 HOH 19  519 278 HOH HOH A . 
H 4 HOH 20  520 38  HOH HOH A . 
H 4 HOH 21  521 402 HOH HOH A . 
H 4 HOH 22  522 102 HOH HOH A . 
H 4 HOH 23  523 397 HOH HOH A . 
H 4 HOH 24  524 37  HOH HOH A . 
H 4 HOH 25  525 76  HOH HOH A . 
H 4 HOH 26  526 46  HOH HOH A . 
H 4 HOH 27  527 8   HOH HOH A . 
H 4 HOH 28  528 199 HOH HOH A . 
H 4 HOH 29  529 131 HOH HOH A . 
H 4 HOH 30  530 353 HOH HOH A . 
H 4 HOH 31  531 216 HOH HOH A . 
H 4 HOH 32  532 335 HOH HOH A . 
H 4 HOH 33  533 142 HOH HOH A . 
H 4 HOH 34  534 327 HOH HOH A . 
H 4 HOH 35  535 184 HOH HOH A . 
H 4 HOH 36  536 60  HOH HOH A . 
H 4 HOH 37  537 19  HOH HOH A . 
H 4 HOH 38  538 212 HOH HOH A . 
H 4 HOH 39  539 284 HOH HOH A . 
H 4 HOH 40  540 78  HOH HOH A . 
H 4 HOH 41  541 59  HOH HOH A . 
H 4 HOH 42  542 319 HOH HOH A . 
H 4 HOH 43  543 224 HOH HOH A . 
H 4 HOH 44  544 21  HOH HOH A . 
H 4 HOH 45  545 201 HOH HOH A . 
H 4 HOH 46  546 72  HOH HOH A . 
H 4 HOH 47  547 139 HOH HOH A . 
H 4 HOH 48  548 323 HOH HOH A . 
H 4 HOH 49  549 17  HOH HOH A . 
H 4 HOH 50  550 219 HOH HOH A . 
H 4 HOH 51  551 20  HOH HOH A . 
H 4 HOH 52  552 79  HOH HOH A . 
H 4 HOH 53  553 68  HOH HOH A . 
H 4 HOH 54  554 9   HOH HOH A . 
H 4 HOH 55  555 66  HOH HOH A . 
H 4 HOH 56  556 104 HOH HOH A . 
H 4 HOH 57  557 152 HOH HOH A . 
H 4 HOH 58  558 156 HOH HOH A . 
H 4 HOH 59  559 55  HOH HOH A . 
H 4 HOH 60  560 246 HOH HOH A . 
H 4 HOH 61  561 86  HOH HOH A . 
H 4 HOH 62  562 316 HOH HOH A . 
H 4 HOH 63  563 53  HOH HOH A . 
H 4 HOH 64  564 85  HOH HOH A . 
H 4 HOH 65  565 130 HOH HOH A . 
H 4 HOH 66  566 7   HOH HOH A . 
H 4 HOH 67  567 367 HOH HOH A . 
H 4 HOH 68  568 128 HOH HOH A . 
H 4 HOH 69  569 90  HOH HOH A . 
H 4 HOH 70  570 115 HOH HOH A . 
H 4 HOH 71  571 25  HOH HOH A . 
H 4 HOH 72  572 58  HOH HOH A . 
H 4 HOH 73  573 180 HOH HOH A . 
H 4 HOH 74  574 103 HOH HOH A . 
H 4 HOH 75  575 205 HOH HOH A . 
H 4 HOH 76  576 373 HOH HOH A . 
H 4 HOH 77  577 11  HOH HOH A . 
H 4 HOH 78  578 120 HOH HOH A . 
H 4 HOH 79  579 83  HOH HOH A . 
H 4 HOH 80  580 218 HOH HOH A . 
H 4 HOH 81  581 356 HOH HOH A . 
H 4 HOH 82  582 379 HOH HOH A . 
H 4 HOH 83  583 43  HOH HOH A . 
H 4 HOH 84  584 5   HOH HOH A . 
H 4 HOH 85  585 74  HOH HOH A . 
H 4 HOH 86  586 31  HOH HOH A . 
H 4 HOH 87  587 73  HOH HOH A . 
H 4 HOH 88  588 29  HOH HOH A . 
H 4 HOH 89  589 57  HOH HOH A . 
H 4 HOH 90  590 80  HOH HOH A . 
H 4 HOH 91  591 223 HOH HOH A . 
H 4 HOH 92  592 309 HOH HOH A . 
H 4 HOH 93  593 89  HOH HOH A . 
H 4 HOH 94  594 93  HOH HOH A . 
H 4 HOH 95  595 28  HOH HOH A . 
H 4 HOH 96  596 33  HOH HOH A . 
H 4 HOH 97  597 52  HOH HOH A . 
H 4 HOH 98  598 183 HOH HOH A . 
H 4 HOH 99  599 16  HOH HOH A . 
H 4 HOH 100 600 312 HOH HOH A . 
H 4 HOH 101 601 82  HOH HOH A . 
H 4 HOH 102 602 54  HOH HOH A . 
H 4 HOH 103 603 15  HOH HOH A . 
H 4 HOH 104 604 34  HOH HOH A . 
H 4 HOH 105 605 75  HOH HOH A . 
H 4 HOH 106 606 317 HOH HOH A . 
H 4 HOH 107 607 2   HOH HOH A . 
H 4 HOH 108 608 376 HOH HOH A . 
H 4 HOH 109 609 151 HOH HOH A . 
H 4 HOH 110 610 81  HOH HOH A . 
H 4 HOH 111 611 182 HOH HOH A . 
H 4 HOH 112 612 111 HOH HOH A . 
H 4 HOH 113 613 4   HOH HOH A . 
H 4 HOH 114 614 262 HOH HOH A . 
H 4 HOH 115 615 305 HOH HOH A . 
H 4 HOH 116 616 215 HOH HOH A . 
H 4 HOH 117 617 71  HOH HOH A . 
H 4 HOH 118 618 12  HOH HOH A . 
H 4 HOH 119 619 141 HOH HOH A . 
H 4 HOH 120 620 181 HOH HOH A . 
H 4 HOH 121 621 96  HOH HOH A . 
H 4 HOH 122 622 84  HOH HOH A . 
H 4 HOH 123 623 210 HOH HOH A . 
H 4 HOH 124 624 39  HOH HOH A . 
H 4 HOH 125 625 395 HOH HOH A . 
H 4 HOH 126 626 171 HOH HOH A . 
H 4 HOH 127 627 22  HOH HOH A . 
H 4 HOH 128 628 286 HOH HOH A . 
H 4 HOH 129 629 49  HOH HOH A . 
H 4 HOH 130 630 99  HOH HOH A . 
H 4 HOH 131 631 186 HOH HOH A . 
H 4 HOH 132 632 105 HOH HOH A . 
H 4 HOH 133 633 148 HOH HOH A . 
H 4 HOH 134 634 114 HOH HOH A . 
H 4 HOH 135 635 214 HOH HOH A . 
H 4 HOH 136 636 92  HOH HOH A . 
H 4 HOH 137 637 222 HOH HOH A . 
H 4 HOH 138 638 133 HOH HOH A . 
H 4 HOH 139 639 231 HOH HOH A . 
H 4 HOH 140 640 233 HOH HOH A . 
H 4 HOH 141 641 396 HOH HOH A . 
H 4 HOH 142 642 338 HOH HOH A . 
H 4 HOH 143 643 1   HOH HOH A . 
H 4 HOH 144 644 265 HOH HOH A . 
H 4 HOH 145 645 384 HOH HOH A . 
H 4 HOH 146 646 94  HOH HOH A . 
H 4 HOH 147 647 187 HOH HOH A . 
H 4 HOH 148 648 14  HOH HOH A . 
H 4 HOH 149 649 229 HOH HOH A . 
H 4 HOH 150 650 157 HOH HOH A . 
H 4 HOH 151 651 185 HOH HOH A . 
H 4 HOH 152 652 146 HOH HOH A . 
H 4 HOH 153 653 174 HOH HOH A . 
H 4 HOH 154 654 91  HOH HOH A . 
H 4 HOH 155 655 87  HOH HOH A . 
H 4 HOH 156 656 3   HOH HOH A . 
H 4 HOH 157 657 113 HOH HOH A . 
H 4 HOH 158 658 160 HOH HOH A . 
H 4 HOH 159 659 127 HOH HOH A . 
H 4 HOH 160 660 191 HOH HOH A . 
H 4 HOH 161 661 63  HOH HOH A . 
H 4 HOH 162 662 217 HOH HOH A . 
H 4 HOH 163 663 190 HOH HOH A . 
H 4 HOH 164 664 207 HOH HOH A . 
H 4 HOH 165 665 372 HOH HOH A . 
H 4 HOH 166 666 116 HOH HOH A . 
H 4 HOH 167 667 64  HOH HOH A . 
H 4 HOH 168 668 144 HOH HOH A . 
H 4 HOH 169 669 13  HOH HOH A . 
H 4 HOH 170 670 202 HOH HOH A . 
H 4 HOH 171 671 295 HOH HOH A . 
H 4 HOH 172 672 134 HOH HOH A . 
H 4 HOH 173 673 136 HOH HOH A . 
H 4 HOH 174 674 228 HOH HOH A . 
H 4 HOH 175 675 333 HOH HOH A . 
H 4 HOH 176 676 56  HOH HOH A . 
H 4 HOH 177 677 189 HOH HOH A . 
H 4 HOH 178 678 288 HOH HOH A . 
H 4 HOH 179 679 32  HOH HOH A . 
H 4 HOH 180 680 107 HOH HOH A . 
H 4 HOH 181 681 42  HOH HOH A . 
H 4 HOH 182 682 26  HOH HOH A . 
H 4 HOH 183 683 27  HOH HOH A . 
H 4 HOH 184 684 240 HOH HOH A . 
H 4 HOH 185 685 126 HOH HOH A . 
H 4 HOH 186 686 124 HOH HOH A . 
H 4 HOH 187 687 23  HOH HOH A . 
H 4 HOH 188 688 61  HOH HOH A . 
H 4 HOH 189 689 294 HOH HOH A . 
H 4 HOH 190 690 166 HOH HOH A . 
H 4 HOH 191 691 30  HOH HOH A . 
H 4 HOH 192 692 150 HOH HOH A . 
H 4 HOH 193 693 101 HOH HOH A . 
H 4 HOH 194 694 36  HOH HOH A . 
H 4 HOH 195 695 168 HOH HOH A . 
H 4 HOH 196 696 95  HOH HOH A . 
H 4 HOH 197 697 342 HOH HOH A . 
H 4 HOH 198 698 200 HOH HOH A . 
H 4 HOH 199 699 399 HOH HOH A . 
H 4 HOH 200 700 18  HOH HOH A . 
H 4 HOH 201 701 145 HOH HOH A . 
H 4 HOH 202 702 62  HOH HOH A . 
H 4 HOH 203 703 297 HOH HOH A . 
H 4 HOH 204 704 188 HOH HOH A . 
H 4 HOH 205 705 300 HOH HOH A . 
H 4 HOH 206 706 350 HOH HOH A . 
H 4 HOH 207 707 70  HOH HOH A . 
H 4 HOH 208 708 140 HOH HOH A . 
H 4 HOH 209 709 69  HOH HOH A . 
H 4 HOH 210 710 365 HOH HOH A . 
H 4 HOH 211 711 169 HOH HOH A . 
H 4 HOH 212 712 362 HOH HOH A . 
H 4 HOH 213 713 106 HOH HOH A . 
H 4 HOH 214 714 10  HOH HOH A . 
H 4 HOH 215 715 165 HOH HOH A . 
H 4 HOH 216 716 220 HOH HOH A . 
H 4 HOH 217 717 35  HOH HOH A . 
H 4 HOH 218 718 387 HOH HOH A . 
H 4 HOH 219 719 122 HOH HOH A . 
H 4 HOH 220 720 177 HOH HOH A . 
H 4 HOH 221 721 314 HOH HOH A . 
H 4 HOH 222 722 261 HOH HOH A . 
H 4 HOH 223 723 45  HOH HOH A . 
H 4 HOH 224 724 100 HOH HOH A . 
H 4 HOH 225 725 277 HOH HOH A . 
H 4 HOH 226 726 77  HOH HOH A . 
H 4 HOH 227 727 48  HOH HOH A . 
H 4 HOH 228 728 299 HOH HOH A . 
H 4 HOH 229 729 6   HOH HOH A . 
H 4 HOH 230 730 329 HOH HOH A . 
H 4 HOH 231 731 176 HOH HOH A . 
H 4 HOH 232 732 88  HOH HOH A . 
H 4 HOH 233 733 301 HOH HOH A . 
H 4 HOH 234 734 161 HOH HOH A . 
H 4 HOH 235 735 119 HOH HOH A . 
H 4 HOH 236 736 375 HOH HOH A . 
H 4 HOH 237 737 380 HOH HOH A . 
H 4 HOH 238 738 398 HOH HOH A . 
H 4 HOH 239 739 408 HOH HOH A . 
H 4 HOH 240 740 178 HOH HOH A . 
H 4 HOH 241 741 272 HOH HOH A . 
H 4 HOH 242 742 389 HOH HOH A . 
H 4 HOH 243 743 385 HOH HOH A . 
H 4 HOH 244 744 318 HOH HOH A . 
H 4 HOH 245 745 378 HOH HOH A . 
H 4 HOH 246 746 360 HOH HOH A . 
H 4 HOH 247 747 175 HOH HOH A . 
H 4 HOH 248 748 313 HOH HOH A . 
H 4 HOH 249 749 315 HOH HOH A . 
H 4 HOH 250 750 361 HOH HOH A . 
H 4 HOH 251 751 196 HOH HOH A . 
H 4 HOH 252 752 129 HOH HOH A . 
H 4 HOH 253 753 326 HOH HOH A . 
H 4 HOH 254 754 132 HOH HOH A . 
H 4 HOH 255 755 121 HOH HOH A . 
H 4 HOH 256 756 170 HOH HOH A . 
H 4 HOH 257 757 198 HOH HOH A . 
H 4 HOH 258 758 351 HOH HOH A . 
H 4 HOH 259 759 355 HOH HOH A . 
H 4 HOH 260 760 311 HOH HOH A . 
H 4 HOH 261 761 393 HOH HOH A . 
H 4 HOH 262 762 321 HOH HOH A . 
H 4 HOH 263 763 340 HOH HOH A . 
H 4 HOH 264 764 290 HOH HOH A . 
H 4 HOH 265 765 163 HOH HOH A . 
H 4 HOH 266 766 388 HOH HOH A . 
H 4 HOH 267 767 47  HOH HOH A . 
H 4 HOH 268 768 41  HOH HOH A . 
H 4 HOH 269 769 230 HOH HOH A . 
H 4 HOH 270 770 381 HOH HOH A . 
H 4 HOH 271 771 154 HOH HOH A . 
H 4 HOH 272 772 343 HOH HOH A . 
H 4 HOH 273 773 346 HOH HOH A . 
H 4 HOH 274 774 173 HOH HOH A . 
H 4 HOH 275 775 65  HOH HOH A . 
H 4 HOH 276 776 221 HOH HOH A . 
H 4 HOH 277 777 248 HOH HOH A . 
H 4 HOH 278 778 357 HOH HOH A . 
H 4 HOH 279 779 203 HOH HOH A . 
H 4 HOH 280 780 382 HOH HOH A . 
H 4 HOH 281 781 345 HOH HOH A . 
H 4 HOH 282 782 232 HOH HOH A . 
H 4 HOH 283 783 192 HOH HOH A . 
H 4 HOH 284 784 359 HOH HOH A . 
H 4 HOH 285 785 209 HOH HOH A . 
H 4 HOH 286 786 149 HOH HOH A . 
H 4 HOH 287 787 330 HOH HOH A . 
H 4 HOH 288 788 281 HOH HOH A . 
H 4 HOH 289 789 204 HOH HOH A . 
H 4 HOH 290 790 227 HOH HOH A . 
H 4 HOH 291 791 291 HOH HOH A . 
H 4 HOH 292 792 268 HOH HOH A . 
H 4 HOH 293 793 197 HOH HOH A . 
H 4 HOH 294 794 97  HOH HOH A . 
H 4 HOH 295 795 308 HOH HOH A . 
H 4 HOH 296 796 354 HOH HOH A . 
H 4 HOH 297 797 267 HOH HOH A . 
H 4 HOH 298 798 324 HOH HOH A . 
H 4 HOH 299 799 302 HOH HOH A . 
H 4 HOH 300 800 125 HOH HOH A . 
H 4 HOH 301 801 167 HOH HOH A . 
H 4 HOH 302 802 276 HOH HOH A . 
H 4 HOH 303 803 334 HOH HOH A . 
H 4 HOH 304 804 251 HOH HOH A . 
H 4 HOH 305 805 296 HOH HOH A . 
H 4 HOH 306 806 256 HOH HOH A . 
H 4 HOH 307 807 208 HOH HOH A . 
H 4 HOH 308 808 273 HOH HOH A . 
H 4 HOH 309 809 195 HOH HOH A . 
H 4 HOH 310 810 344 HOH HOH A . 
H 4 HOH 311 811 137 HOH HOH A . 
H 4 HOH 312 812 40  HOH HOH A . 
H 4 HOH 313 813 358 HOH HOH A . 
H 4 HOH 314 814 320 HOH HOH A . 
H 4 HOH 315 815 194 HOH HOH A . 
H 4 HOH 316 816 236 HOH HOH A . 
H 4 HOH 317 817 159 HOH HOH A . 
H 4 HOH 318 818 179 HOH HOH A . 
H 4 HOH 319 819 155 HOH HOH A . 
H 4 HOH 320 820 406 HOH HOH A . 
H 4 HOH 321 821 386 HOH HOH A . 
H 4 HOH 322 822 280 HOH HOH A . 
H 4 HOH 323 823 400 HOH HOH A . 
H 4 HOH 324 824 213 HOH HOH A . 
H 4 HOH 325 825 283 HOH HOH A . 
H 4 HOH 326 826 108 HOH HOH A . 
H 4 HOH 327 827 266 HOH HOH A . 
H 4 HOH 328 828 263 HOH HOH A . 
H 4 HOH 329 829 242 HOH HOH A . 
H 4 HOH 330 830 235 HOH HOH A . 
H 4 HOH 331 831 247 HOH HOH A . 
H 4 HOH 332 832 287 HOH HOH A . 
H 4 HOH 333 833 258 HOH HOH A . 
H 4 HOH 334 834 282 HOH HOH A . 
H 4 HOH 335 835 24  HOH HOH A . 
H 4 HOH 336 836 352 HOH HOH A . 
H 4 HOH 337 837 347 HOH HOH A . 
H 4 HOH 338 838 226 HOH HOH A . 
H 4 HOH 339 839 245 HOH HOH A . 
H 4 HOH 340 840 243 HOH HOH A . 
H 4 HOH 341 841 339 HOH HOH A . 
H 4 HOH 342 842 117 HOH HOH A . 
H 4 HOH 343 843 298 HOH HOH A . 
H 4 HOH 344 844 260 HOH HOH A . 
H 4 HOH 345 845 407 HOH HOH A . 
H 4 HOH 346 846 303 HOH HOH A . 
H 4 HOH 347 847 250 HOH HOH A . 
H 4 HOH 348 848 254 HOH HOH A . 
H 4 HOH 349 849 162 HOH HOH A . 
H 4 HOH 350 850 206 HOH HOH A . 
H 4 HOH 351 851 401 HOH HOH A . 
H 4 HOH 352 852 44  HOH HOH A . 
H 4 HOH 353 853 241 HOH HOH A . 
H 4 HOH 354 854 293 HOH HOH A . 
H 4 HOH 355 855 98  HOH HOH A . 
H 4 HOH 356 856 239 HOH HOH A . 
H 4 HOH 357 857 403 HOH HOH A . 
H 4 HOH 358 858 332 HOH HOH A . 
H 4 HOH 359 859 348 HOH HOH A . 
H 4 HOH 360 860 252 HOH HOH A . 
H 4 HOH 361 861 363 HOH HOH A . 
H 4 HOH 362 862 331 HOH HOH A . 
H 4 HOH 363 863 264 HOH HOH A . 
H 4 HOH 364 864 244 HOH HOH A . 
H 4 HOH 365 865 274 HOH HOH A . 
H 4 HOH 366 866 337 HOH HOH A . 
H 4 HOH 367 867 249 HOH HOH A . 
H 4 HOH 368 868 253 HOH HOH A . 
H 4 HOH 369 869 109 HOH HOH A . 
H 4 HOH 370 870 304 HOH HOH A . 
H 4 HOH 371 871 143 HOH HOH A . 
H 4 HOH 372 872 255 HOH HOH A . 
H 4 HOH 373 873 211 HOH HOH A . 
H 4 HOH 374 874 285 HOH HOH A . 
H 4 HOH 375 875 138 HOH HOH A . 
H 4 HOH 376 876 374 HOH HOH A . 
H 4 HOH 377 877 371 HOH HOH A . 
H 4 HOH 378 878 193 HOH HOH A . 
H 4 HOH 379 879 325 HOH HOH A . 
H 4 HOH 380 880 237 HOH HOH A . 
H 4 HOH 381 881 336 HOH HOH A . 
H 4 HOH 382 882 238 HOH HOH A . 
H 4 HOH 383 883 158 HOH HOH A . 
H 4 HOH 384 884 349 HOH HOH A . 
H 4 HOH 385 885 383 HOH HOH A . 
H 4 HOH 386 886 259 HOH HOH A . 
H 4 HOH 387 887 257 HOH HOH A . 
H 4 HOH 388 888 135 HOH HOH A . 
H 4 HOH 389 889 409 HOH HOH A . 
H 4 HOH 390 890 392 HOH HOH A . 
H 4 HOH 391 891 366 HOH HOH A . 
H 4 HOH 392 892 390 HOH HOH A . 
H 4 HOH 393 893 394 HOH HOH A . 
H 4 HOH 394 894 147 HOH HOH A . 
H 4 HOH 395 895 225 HOH HOH A . 
H 4 HOH 396 896 270 HOH HOH A . 
H 4 HOH 397 897 368 HOH HOH A . 
H 4 HOH 398 898 307 HOH HOH A . 
H 4 HOH 399 899 405 HOH HOH A . 
H 4 HOH 400 900 279 HOH HOH A . 
H 4 HOH 401 901 377 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8YD9 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     45.785 
_cell.length_a_esd                 ? 
_cell.length_b                     85.643 
_cell.length_b_esd                 ? 
_cell.length_c                     126.935 
_cell.length_c_esd                 ? 
_cell.volume                       497733.048 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8YD9 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8YD9 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.01 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          59.13 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'anmonium acetate, HEPES, PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-10-29 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    mirrors 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SPRING-8 BEAMLINE BL44XU' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL44XU 
_diffrn_source.pdbx_synchrotron_site       SPring-8 
# 
_reflns.B_iso_Wilson_estimate                          31.85 
_reflns.entry_id                                       8YD9 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.66 
_reflns.d_resolution_low                               45.61 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     59663 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          8.34 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.996 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.66 
_reflns_shell.d_res_low                                     1.76 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             59663 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.996 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               45.42 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8YD9 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.66 
_refine.ls_d_res_low                             45.61 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     59663 
_refine.ls_number_reflns_R_free                  3074 
_refine.ls_number_reflns_R_work                  58428 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.81 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1627 
_refine.ls_R_factor_R_free                       0.2049 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1604 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 20.8297 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2291 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.66 
_refine_hist.d_res_low                        45.61 
_refine_hist.number_atoms_solvent             401 
_refine_hist.number_atoms_total               3292 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2825 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         66 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0077 ? 3173 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9582 ? 4332 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0572 ? 476  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0093 ? 558  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 7.2613 ? 438  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.66 1.67  . . 134 2549 97.67  . . . . 0.3044 . . . . . . . . . . . 0.3703 
'X-RAY DIFFRACTION' 1.67 1.70  . . 139 2630 100.00 . . . . 0.2566 . . . . . . . . . . . 0.3139 
'X-RAY DIFFRACTION' 1.70 1.73  . . 136 2589 100.00 . . . . 0.2317 . . . . . . . . . . . 0.3011 
'X-RAY DIFFRACTION' 1.73 1.76  . . 140 2666 100.00 . . . . 0.2363 . . . . . . . . . . . 0.2816 
'X-RAY DIFFRACTION' 1.76 1.79  . . 138 2607 100.00 . . . . 0.2503 . . . . . . . . . . . 0.3343 
'X-RAY DIFFRACTION' 1.79 1.83  . . 138 2633 100.00 . . . . 0.2573 . . . . . . . . . . . 0.3259 
'X-RAY DIFFRACTION' 1.83 1.87  . . 139 2630 100.00 . . . . 0.2413 . . . . . . . . . . . 0.3186 
'X-RAY DIFFRACTION' 1.87 1.91  . . 139 2638 100.00 . . . . 0.2078 . . . . . . . . . . . 0.2854 
'X-RAY DIFFRACTION' 1.91 1.96  . . 137 2607 100.00 . . . . 0.1667 . . . . . . . . . . . 0.2189 
'X-RAY DIFFRACTION' 1.96 2.01  . . 139 2645 99.96  . . . . 0.1665 . . . . . . . . . . . 0.2011 
'X-RAY DIFFRACTION' 2.01 2.07  . . 139 2646 99.96  . . . . 0.1602 . . . . . . . . . . . 0.2312 
'X-RAY DIFFRACTION' 2.07 2.14  . . 138 2628 100.00 . . . . 0.1637 . . . . . . . . . . . 0.1921 
'X-RAY DIFFRACTION' 2.14 2.21  . . 141 2660 99.93  . . . . 0.1651 . . . . . . . . . . . 0.2093 
'X-RAY DIFFRACTION' 2.21 2.30  . . 138 2659 100.00 . . . . 0.1657 . . . . . . . . . . . 0.2187 
'X-RAY DIFFRACTION' 2.30 2.41  . . 140 2650 100.00 . . . . 0.1560 . . . . . . . . . . . 0.2530 
'X-RAY DIFFRACTION' 2.41 2.53  . . 140 2670 99.82  . . . . 0.1584 . . . . . . . . . . . 0.1900 
'X-RAY DIFFRACTION' 2.53 2.69  . . 142 2684 99.96  . . . . 0.1568 . . . . . . . . . . . 0.1973 
'X-RAY DIFFRACTION' 2.69 2.90  . . 139 2642 99.86  . . . . 0.1690 . . . . . . . . . . . 0.1937 
'X-RAY DIFFRACTION' 2.90 3.19  . . 142 2696 99.93  . . . . 0.1673 . . . . . . . . . . . 0.2274 
'X-RAY DIFFRACTION' 3.19 3.65  . . 141 2687 99.44  . . . . 0.1414 . . . . . . . . . . . 0.1879 
'X-RAY DIFFRACTION' 3.65 4.60  . . 145 2745 99.55  . . . . 0.1255 . . . . . . . . . . . 0.1737 
'X-RAY DIFFRACTION' 4.61 37.13 . . 150 2867 99.80  . . . . 0.1629 . . . . . . . . . . . 0.1828 
# 
_struct.entry_id                     8YD9 
_struct.title                        'Crystal structure of p38alpha with an allosteric inhibitor 3' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8YD9 
_struct_keywords.text            'Inhibitor, STRUCTURAL GENOMICS, TRANSFERASE-TRANSFERASE INHIBITOR complex' 
_struct_keywords.pdbx_keywords   'TRANSFERASE/TRANSFERASE INHIBITOR' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    MK14_HUMAN 
_struct_ref.pdbx_db_accession          Q16539 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKH
ENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE
DCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVA
DPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8YD9 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 360 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q16539 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  360 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       360 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 61  ? MET A 78  ? SER A 61  MET A 78  1 ? 18 
HELX_P HELX_P2  AA2 SER A 95  ? PHE A 99  ? SER A 95  PHE A 99  5 ? 5  
HELX_P HELX_P3  AA3 LEU A 113 ? LYS A 118 ? LEU A 113 LYS A 118 1 ? 6  
HELX_P HELX_P4  AA4 THR A 123 ? ALA A 144 ? THR A 123 ALA A 144 1 ? 22 
HELX_P HELX_P5  AA5 LYS A 152 ? SER A 154 ? LYS A 152 SER A 154 5 ? 3  
HELX_P HELX_P6  AA6 ASP A 176 ? THR A 180 ? ASP A 176 THR A 180 5 ? 5  
HELX_P HELX_P7  AA7 VAL A 183 ? TYR A 188 ? VAL A 183 TYR A 188 1 ? 6  
HELX_P HELX_P8  AA8 ALA A 190 ? LEU A 195 ? ALA A 190 LEU A 195 1 ? 6  
HELX_P HELX_P9  AA9 GLN A 202 ? GLY A 219 ? GLN A 202 GLY A 219 1 ? 18 
HELX_P HELX_P10 AB1 ASP A 227 ? GLY A 240 ? ASP A 227 GLY A 240 1 ? 14 
HELX_P HELX_P11 AB2 GLY A 243 ? LYS A 249 ? GLY A 243 LYS A 249 1 ? 7  
HELX_P HELX_P12 AB3 SER A 254 ? ILE A 259 ? SER A 254 ILE A 259 1 ? 6  
HELX_P HELX_P13 AB4 GLN A 260 ? LEU A 262 ? GLN A 260 LEU A 262 5 ? 3  
HELX_P HELX_P14 AB5 ASN A 269 ? PHE A 274 ? ASN A 269 PHE A 274 1 ? 6  
HELX_P HELX_P15 AB6 ASN A 278 ? LEU A 289 ? ASN A 278 LEU A 289 1 ? 12 
HELX_P HELX_P16 AB7 THR A 298 ? ALA A 304 ? THR A 298 ALA A 304 1 ? 7  
HELX_P HELX_P17 AB8 HIS A 305 ? ALA A 309 ? HIS A 305 ALA A 309 5 ? 5  
HELX_P HELX_P18 AB9 GLN A 325 ? ARG A 330 ? GLN A 325 ARG A 330 5 ? 6  
HELX_P HELX_P19 AC1 LEU A 333 ? SER A 347 ? LEU A 333 SER A 347 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 5 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 8   ? GLN A 11  ? PHE A 8   GLN A 11  
AA1 2 TRP A 18  ? PRO A 21  ? TRP A 18  PRO A 21  
AA2 1 TYR A 24  ? SER A 32  ? TYR A 24  SER A 32  
AA2 2 GLY A 36  ? ASP A 43  ? GLY A 36  ASP A 43  
AA2 3 ARG A 49  ? LEU A 55  ? ARG A 49  LEU A 55  
AA2 4 TYR A 103 ? HIS A 107 ? TYR A 103 HIS A 107 
AA2 5 ASP A 88  ? PHE A 90  ? ASP A 88  PHE A 90  
AA3 1 LEU A 156 ? VAL A 158 ? LEU A 156 VAL A 158 
AA3 2 LEU A 164 ? ILE A 166 ? LEU A 164 ILE A 166 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 11  ? N GLN A 11  O TRP A 18  ? O TRP A 18  
AA2 1 2 N GLY A 31  ? N GLY A 31  O VAL A 38  ? O VAL A 38  
AA2 2 3 N CYS A 39  ? N CYS A 39  O VAL A 52  ? O VAL A 52  
AA2 3 4 N ALA A 51  ? N ALA A 51  O THR A 106 ? O THR A 106 
AA2 4 5 O VAL A 105 ? O VAL A 105 N ASP A 88  ? N ASP A 88  
AA3 1 2 N ALA A 157 ? N ALA A 157 O LYS A 165 ? O LYS A 165 
# 
_pdbx_entry_details.entry_id                   8YD9 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O A HOH 798 ? ? O A HOH 879 ? ? 2.05 
2 1 O A HOH 506 ? ? O A HOH 731 ? ? 2.09 
3 1 O A HOH 737 ? ? O A HOH 875 ? ? 2.11 
4 1 O A HOH 628 ? ? O A HOH 719 ? ? 2.16 
5 1 O A HOH 770 ? ? O A HOH 780 ? ? 2.17 
6 1 O A HOH 560 ? ? O A HOH 846 ? ? 2.18 
7 1 O A HOH 640 ? ? O A HOH 863 ? ? 2.18 
8 1 O A HOH 778 ? ? O A HOH 845 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 13  ? ? 59.23   -129.58 
2  1 ASN A 14  ? ? -45.47  -108.75 
3  1 ASN A 115 ? ? -72.60  20.03   
4  1 ILE A 116 ? ? -131.08 -35.40  
5  1 LYS A 118 ? ? -105.36 74.38   
6  1 CYS A 119 ? ? -169.36 -59.84  
7  1 LEU A 122 ? ? 50.20   117.08  
8  1 ARG A 149 ? ? 86.21   -14.87  
9  1 ASP A 150 ? ? -143.21 38.35   
10 1 ASP A 150 ? ? -143.21 40.14   
11 1 CYS A 162 ? ? 57.18   19.80   
12 1 ASP A 168 ? A 41.78   72.62   
13 1 ASP A 168 ? B 78.61   -94.83  
14 1 PHE A 169 ? B 93.32   118.42  
15 1 ALA A 172 ? A 84.60   85.93   
16 1 ARG A 173 ? A -149.33 -93.52  
17 1 ARG A 173 ? B 80.42   21.32   
18 1 HIS A 174 ? A 14.47   91.27   
19 1 HIS A 174 ? B 6.36    123.51  
20 1 ASN A 257 ? A 80.37   -53.59  
21 1 LEU A 289 ? ? -94.75  59.34   
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 898 ? 5.93 . 
2 1 O ? A HOH 899 ? 6.13 . 
3 1 O ? A HOH 900 ? 6.26 . 
4 1 O ? A HOH 901 ? 6.34 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A SER 2   ? A SER 2   
3  1 Y 1 A GLN 3   ? A GLN 3   
4  1 Y 1 A ASP 354 ? A ASP 354 
5  1 Y 1 A GLN 355 ? A GLN 355 
6  1 Y 1 A GLU 356 ? A GLU 356 
7  1 Y 1 A GLU 357 ? A GLU 357 
8  1 Y 1 A MET 358 ? A MET 358 
9  1 Y 1 A GLU 359 ? A GLU 359 
10 1 Y 1 A SER 360 ? A SER 360 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
6GI C01  C Y N 1   
6GI C02  C Y N 2   
6GI C03  C Y N 3   
6GI C04  C Y N 4   
6GI C05  C Y N 5   
6GI C08  C Y N 6   
6GI C09  C Y N 7   
6GI C10  C N N 8   
6GI C12  C Y N 9   
6GI C13  C Y N 10  
6GI C14  C Y N 11  
6GI C15  C Y N 12  
6GI C16  C Y N 13  
6GI C17  C Y N 14  
6GI C18  C N R 15  
6GI C20  C Y N 16  
6GI C22  C N N 17  
6GI C25  C Y N 18  
6GI C26  C Y N 19  
6GI C28  C Y N 20  
6GI C29  C Y N 21  
6GI C30  C Y N 22  
6GI C31  C Y N 23  
6GI C33  C N N 24  
6GI C34  C N N 25  
6GI C35  C N N 26  
6GI N06  N Y N 27  
6GI N07  N Y N 28  
6GI N19  N Y N 29  
6GI N21  N N N 30  
6GI N23  N N N 31  
6GI N24  N N N 32  
6GI N27  N Y N 33  
6GI O11  O N N 34  
6GI O32  O N N 35  
6GI O36  O N N 36  
6GI H1   H N N 37  
6GI H2   H N N 38  
6GI H3   H N N 39  
6GI H4   H N N 40  
6GI H5   H N N 41  
6GI H6   H N N 42  
6GI H7   H N N 43  
6GI H8   H N N 44  
6GI H9   H N N 45  
6GI H10  H N N 46  
6GI H11  H N N 47  
6GI H12  H N N 48  
6GI H14  H N N 49  
6GI H15  H N N 50  
6GI H16  H N N 51  
6GI H17  H N N 52  
6GI H18  H N N 53  
6GI H19  H N N 54  
6GI H20  H N N 55  
6GI H21  H N N 56  
6GI H22  H N N 57  
6GI H24  H N N 58  
6GI H25  H N N 59  
ALA N    N N N 60  
ALA CA   C N S 61  
ALA C    C N N 62  
ALA O    O N N 63  
ALA CB   C N N 64  
ALA OXT  O N N 65  
ALA H    H N N 66  
ALA H2   H N N 67  
ALA HA   H N N 68  
ALA HB1  H N N 69  
ALA HB2  H N N 70  
ALA HB3  H N N 71  
ALA HXT  H N N 72  
ARG N    N N N 73  
ARG CA   C N S 74  
ARG C    C N N 75  
ARG O    O N N 76  
ARG CB   C N N 77  
ARG CG   C N N 78  
ARG CD   C N N 79  
ARG NE   N N N 80  
ARG CZ   C N N 81  
ARG NH1  N N N 82  
ARG NH2  N N N 83  
ARG OXT  O N N 84  
ARG H    H N N 85  
ARG H2   H N N 86  
ARG HA   H N N 87  
ARG HB2  H N N 88  
ARG HB3  H N N 89  
ARG HG2  H N N 90  
ARG HG3  H N N 91  
ARG HD2  H N N 92  
ARG HD3  H N N 93  
ARG HE   H N N 94  
ARG HH11 H N N 95  
ARG HH12 H N N 96  
ARG HH21 H N N 97  
ARG HH22 H N N 98  
ARG HXT  H N N 99  
ASN N    N N N 100 
ASN CA   C N S 101 
ASN C    C N N 102 
ASN O    O N N 103 
ASN CB   C N N 104 
ASN CG   C N N 105 
ASN OD1  O N N 106 
ASN ND2  N N N 107 
ASN OXT  O N N 108 
ASN H    H N N 109 
ASN H2   H N N 110 
ASN HA   H N N 111 
ASN HB2  H N N 112 
ASN HB3  H N N 113 
ASN HD21 H N N 114 
ASN HD22 H N N 115 
ASN HXT  H N N 116 
ASP N    N N N 117 
ASP CA   C N S 118 
ASP C    C N N 119 
ASP O    O N N 120 
ASP CB   C N N 121 
ASP CG   C N N 122 
ASP OD1  O N N 123 
ASP OD2  O N N 124 
ASP OXT  O N N 125 
ASP H    H N N 126 
ASP H2   H N N 127 
ASP HA   H N N 128 
ASP HB2  H N N 129 
ASP HB3  H N N 130 
ASP HD2  H N N 131 
ASP HXT  H N N 132 
CYS N    N N N 133 
CYS CA   C N R 134 
CYS C    C N N 135 
CYS O    O N N 136 
CYS CB   C N N 137 
CYS SG   S N N 138 
CYS OXT  O N N 139 
CYS H    H N N 140 
CYS H2   H N N 141 
CYS HA   H N N 142 
CYS HB2  H N N 143 
CYS HB3  H N N 144 
CYS HG   H N N 145 
CYS HXT  H N N 146 
GLN N    N N N 147 
GLN CA   C N S 148 
GLN C    C N N 149 
GLN O    O N N 150 
GLN CB   C N N 151 
GLN CG   C N N 152 
GLN CD   C N N 153 
GLN OE1  O N N 154 
GLN NE2  N N N 155 
GLN OXT  O N N 156 
GLN H    H N N 157 
GLN H2   H N N 158 
GLN HA   H N N 159 
GLN HB2  H N N 160 
GLN HB3  H N N 161 
GLN HG2  H N N 162 
GLN HG3  H N N 163 
GLN HE21 H N N 164 
GLN HE22 H N N 165 
GLN HXT  H N N 166 
GLU N    N N N 167 
GLU CA   C N S 168 
GLU C    C N N 169 
GLU O    O N N 170 
GLU CB   C N N 171 
GLU CG   C N N 172 
GLU CD   C N N 173 
GLU OE1  O N N 174 
GLU OE2  O N N 175 
GLU OXT  O N N 176 
GLU H    H N N 177 
GLU H2   H N N 178 
GLU HA   H N N 179 
GLU HB2  H N N 180 
GLU HB3  H N N 181 
GLU HG2  H N N 182 
GLU HG3  H N N 183 
GLU HE2  H N N 184 
GLU HXT  H N N 185 
GLY N    N N N 186 
GLY CA   C N N 187 
GLY C    C N N 188 
GLY O    O N N 189 
GLY OXT  O N N 190 
GLY H    H N N 191 
GLY H2   H N N 192 
GLY HA2  H N N 193 
GLY HA3  H N N 194 
GLY HXT  H N N 195 
GOL C1   C N N 196 
GOL O1   O N N 197 
GOL C2   C N N 198 
GOL O2   O N N 199 
GOL C3   C N N 200 
GOL O3   O N N 201 
GOL H11  H N N 202 
GOL H12  H N N 203 
GOL HO1  H N N 204 
GOL H2   H N N 205 
GOL HO2  H N N 206 
GOL H31  H N N 207 
GOL H32  H N N 208 
GOL HO3  H N N 209 
HIS N    N N N 210 
HIS CA   C N S 211 
HIS C    C N N 212 
HIS O    O N N 213 
HIS CB   C N N 214 
HIS CG   C Y N 215 
HIS ND1  N Y N 216 
HIS CD2  C Y N 217 
HIS CE1  C Y N 218 
HIS NE2  N Y N 219 
HIS OXT  O N N 220 
HIS H    H N N 221 
HIS H2   H N N 222 
HIS HA   H N N 223 
HIS HB2  H N N 224 
HIS HB3  H N N 225 
HIS HD1  H N N 226 
HIS HD2  H N N 227 
HIS HE1  H N N 228 
HIS HE2  H N N 229 
HIS HXT  H N N 230 
HOH O    O N N 231 
HOH H1   H N N 232 
HOH H2   H N N 233 
ILE N    N N N 234 
ILE CA   C N S 235 
ILE C    C N N 236 
ILE O    O N N 237 
ILE CB   C N S 238 
ILE CG1  C N N 239 
ILE CG2  C N N 240 
ILE CD1  C N N 241 
ILE OXT  O N N 242 
ILE H    H N N 243 
ILE H2   H N N 244 
ILE HA   H N N 245 
ILE HB   H N N 246 
ILE HG12 H N N 247 
ILE HG13 H N N 248 
ILE HG21 H N N 249 
ILE HG22 H N N 250 
ILE HG23 H N N 251 
ILE HD11 H N N 252 
ILE HD12 H N N 253 
ILE HD13 H N N 254 
ILE HXT  H N N 255 
LEU N    N N N 256 
LEU CA   C N S 257 
LEU C    C N N 258 
LEU O    O N N 259 
LEU CB   C N N 260 
LEU CG   C N N 261 
LEU CD1  C N N 262 
LEU CD2  C N N 263 
LEU OXT  O N N 264 
LEU H    H N N 265 
LEU H2   H N N 266 
LEU HA   H N N 267 
LEU HB2  H N N 268 
LEU HB3  H N N 269 
LEU HG   H N N 270 
LEU HD11 H N N 271 
LEU HD12 H N N 272 
LEU HD13 H N N 273 
LEU HD21 H N N 274 
LEU HD22 H N N 275 
LEU HD23 H N N 276 
LEU HXT  H N N 277 
LYS N    N N N 278 
LYS CA   C N S 279 
LYS C    C N N 280 
LYS O    O N N 281 
LYS CB   C N N 282 
LYS CG   C N N 283 
LYS CD   C N N 284 
LYS CE   C N N 285 
LYS NZ   N N N 286 
LYS OXT  O N N 287 
LYS H    H N N 288 
LYS H2   H N N 289 
LYS HA   H N N 290 
LYS HB2  H N N 291 
LYS HB3  H N N 292 
LYS HG2  H N N 293 
LYS HG3  H N N 294 
LYS HD2  H N N 295 
LYS HD3  H N N 296 
LYS HE2  H N N 297 
LYS HE3  H N N 298 
LYS HZ1  H N N 299 
LYS HZ2  H N N 300 
LYS HZ3  H N N 301 
LYS HXT  H N N 302 
MET N    N N N 303 
MET CA   C N S 304 
MET C    C N N 305 
MET O    O N N 306 
MET CB   C N N 307 
MET CG   C N N 308 
MET SD   S N N 309 
MET CE   C N N 310 
MET OXT  O N N 311 
MET H    H N N 312 
MET H2   H N N 313 
MET HA   H N N 314 
MET HB2  H N N 315 
MET HB3  H N N 316 
MET HG2  H N N 317 
MET HG3  H N N 318 
MET HE1  H N N 319 
MET HE2  H N N 320 
MET HE3  H N N 321 
MET HXT  H N N 322 
PHE N    N N N 323 
PHE CA   C N S 324 
PHE C    C N N 325 
PHE O    O N N 326 
PHE CB   C N N 327 
PHE CG   C Y N 328 
PHE CD1  C Y N 329 
PHE CD2  C Y N 330 
PHE CE1  C Y N 331 
PHE CE2  C Y N 332 
PHE CZ   C Y N 333 
PHE OXT  O N N 334 
PHE H    H N N 335 
PHE H2   H N N 336 
PHE HA   H N N 337 
PHE HB2  H N N 338 
PHE HB3  H N N 339 
PHE HD1  H N N 340 
PHE HD2  H N N 341 
PHE HE1  H N N 342 
PHE HE2  H N N 343 
PHE HZ   H N N 344 
PHE HXT  H N N 345 
PRO N    N N N 346 
PRO CA   C N S 347 
PRO C    C N N 348 
PRO O    O N N 349 
PRO CB   C N N 350 
PRO CG   C N N 351 
PRO CD   C N N 352 
PRO OXT  O N N 353 
PRO H    H N N 354 
PRO HA   H N N 355 
PRO HB2  H N N 356 
PRO HB3  H N N 357 
PRO HG2  H N N 358 
PRO HG3  H N N 359 
PRO HD2  H N N 360 
PRO HD3  H N N 361 
PRO HXT  H N N 362 
SER N    N N N 363 
SER CA   C N S 364 
SER C    C N N 365 
SER O    O N N 366 
SER CB   C N N 367 
SER OG   O N N 368 
SER OXT  O N N 369 
SER H    H N N 370 
SER H2   H N N 371 
SER HA   H N N 372 
SER HB2  H N N 373 
SER HB3  H N N 374 
SER HG   H N N 375 
SER HXT  H N N 376 
THR N    N N N 377 
THR CA   C N S 378 
THR C    C N N 379 
THR O    O N N 380 
THR CB   C N R 381 
THR OG1  O N N 382 
THR CG2  C N N 383 
THR OXT  O N N 384 
THR H    H N N 385 
THR H2   H N N 386 
THR HA   H N N 387 
THR HB   H N N 388 
THR HG1  H N N 389 
THR HG21 H N N 390 
THR HG22 H N N 391 
THR HG23 H N N 392 
THR HXT  H N N 393 
TRP N    N N N 394 
TRP CA   C N S 395 
TRP C    C N N 396 
TRP O    O N N 397 
TRP CB   C N N 398 
TRP CG   C Y N 399 
TRP CD1  C Y N 400 
TRP CD2  C Y N 401 
TRP NE1  N Y N 402 
TRP CE2  C Y N 403 
TRP CE3  C Y N 404 
TRP CZ2  C Y N 405 
TRP CZ3  C Y N 406 
TRP CH2  C Y N 407 
TRP OXT  O N N 408 
TRP H    H N N 409 
TRP H2   H N N 410 
TRP HA   H N N 411 
TRP HB2  H N N 412 
TRP HB3  H N N 413 
TRP HD1  H N N 414 
TRP HE1  H N N 415 
TRP HE3  H N N 416 
TRP HZ2  H N N 417 
TRP HZ3  H N N 418 
TRP HH2  H N N 419 
TRP HXT  H N N 420 
TYR N    N N N 421 
TYR CA   C N S 422 
TYR C    C N N 423 
TYR O    O N N 424 
TYR CB   C N N 425 
TYR CG   C Y N 426 
TYR CD1  C Y N 427 
TYR CD2  C Y N 428 
TYR CE1  C Y N 429 
TYR CE2  C Y N 430 
TYR CZ   C Y N 431 
TYR OH   O N N 432 
TYR OXT  O N N 433 
TYR H    H N N 434 
TYR H2   H N N 435 
TYR HA   H N N 436 
TYR HB2  H N N 437 
TYR HB3  H N N 438 
TYR HD1  H N N 439 
TYR HD2  H N N 440 
TYR HE1  H N N 441 
TYR HE2  H N N 442 
TYR HH   H N N 443 
TYR HXT  H N N 444 
VAL N    N N N 445 
VAL CA   C N S 446 
VAL C    C N N 447 
VAL O    O N N 448 
VAL CB   C N N 449 
VAL CG1  C N N 450 
VAL CG2  C N N 451 
VAL OXT  O N N 452 
VAL H    H N N 453 
VAL H2   H N N 454 
VAL HA   H N N 455 
VAL HB   H N N 456 
VAL HG11 H N N 457 
VAL HG12 H N N 458 
VAL HG13 H N N 459 
VAL HG21 H N N 460 
VAL HG22 H N N 461 
VAL HG23 H N N 462 
VAL HXT  H N N 463 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
6GI C01 C02  doub Y N 1   
6GI C01 N06  sing Y N 2   
6GI C02 C03  sing Y N 3   
6GI C03 C04  doub Y N 4   
6GI C04 C05  sing Y N 5   
6GI C05 N06  sing Y N 6   
6GI C05 N07  doub Y N 7   
6GI C08 C09  doub Y N 8   
6GI C08 C10  sing N N 9   
6GI C08 N07  sing Y N 10  
6GI C09 N06  sing Y N 11  
6GI C10 O11  sing N N 12  
6GI C12 C13  doub Y N 13  
6GI C12 C17  sing Y N 14  
6GI C12 O11  sing N N 15  
6GI C13 C14  sing Y N 16  
6GI C14 C15  doub Y N 17  
6GI C15 C16  sing Y N 18  
6GI C15 C18  sing N N 19  
6GI C16 C17  doub Y N 20  
6GI C18 N19  sing N N 21  
6GI C20 N19  sing Y N 22  
6GI C20 N21  sing N N 23  
6GI C20 N27  doub Y N 24  
6GI C22 N21  doub N N 25  
6GI C22 N23  sing N N 26  
6GI C22 N24  sing N N 27  
6GI C25 C26  doub Y N 28  
6GI C25 C28  sing Y N 29  
6GI C25 N19  sing Y N 30  
6GI C26 C31  sing Y N 31  
6GI C26 N27  sing Y N 32  
6GI C28 C29  doub Y N 33  
6GI C29 C30  sing Y N 34  
6GI C29 O32  sing N N 35  
6GI C30 C31  doub Y N 36  
6GI C30 O36  sing N N 37  
6GI C33 C34  sing N N 38  
6GI C33 O32  sing N N 39  
6GI C34 C35  sing N N 40  
6GI C35 O36  sing N N 41  
6GI C01 H1   sing N N 42  
6GI C02 H2   sing N N 43  
6GI C03 H3   sing N N 44  
6GI C04 H4   sing N N 45  
6GI C09 H5   sing N N 46  
6GI C10 H6   sing N N 47  
6GI C10 H7   sing N N 48  
6GI C13 H8   sing N N 49  
6GI C14 H9   sing N N 50  
6GI C16 H10  sing N N 51  
6GI C17 H11  sing N N 52  
6GI C18 H12  sing N N 53  
6GI C28 H14  sing N N 54  
6GI C31 H15  sing N N 55  
6GI C33 H16  sing N N 56  
6GI C33 H17  sing N N 57  
6GI C34 H18  sing N N 58  
6GI C34 H19  sing N N 59  
6GI C35 H20  sing N N 60  
6GI C35 H21  sing N N 61  
6GI N23 H22  sing N N 62  
6GI N24 H24  sing N N 63  
6GI N24 H25  sing N N 64  
6GI C18 N23  sing N N 65  
ALA N   CA   sing N N 66  
ALA N   H    sing N N 67  
ALA N   H2   sing N N 68  
ALA CA  C    sing N N 69  
ALA CA  CB   sing N N 70  
ALA CA  HA   sing N N 71  
ALA C   O    doub N N 72  
ALA C   OXT  sing N N 73  
ALA CB  HB1  sing N N 74  
ALA CB  HB2  sing N N 75  
ALA CB  HB3  sing N N 76  
ALA OXT HXT  sing N N 77  
ARG N   CA   sing N N 78  
ARG N   H    sing N N 79  
ARG N   H2   sing N N 80  
ARG CA  C    sing N N 81  
ARG CA  CB   sing N N 82  
ARG CA  HA   sing N N 83  
ARG C   O    doub N N 84  
ARG C   OXT  sing N N 85  
ARG CB  CG   sing N N 86  
ARG CB  HB2  sing N N 87  
ARG CB  HB3  sing N N 88  
ARG CG  CD   sing N N 89  
ARG CG  HG2  sing N N 90  
ARG CG  HG3  sing N N 91  
ARG CD  NE   sing N N 92  
ARG CD  HD2  sing N N 93  
ARG CD  HD3  sing N N 94  
ARG NE  CZ   sing N N 95  
ARG NE  HE   sing N N 96  
ARG CZ  NH1  sing N N 97  
ARG CZ  NH2  doub N N 98  
ARG NH1 HH11 sing N N 99  
ARG NH1 HH12 sing N N 100 
ARG NH2 HH21 sing N N 101 
ARG NH2 HH22 sing N N 102 
ARG OXT HXT  sing N N 103 
ASN N   CA   sing N N 104 
ASN N   H    sing N N 105 
ASN N   H2   sing N N 106 
ASN CA  C    sing N N 107 
ASN CA  CB   sing N N 108 
ASN CA  HA   sing N N 109 
ASN C   O    doub N N 110 
ASN C   OXT  sing N N 111 
ASN CB  CG   sing N N 112 
ASN CB  HB2  sing N N 113 
ASN CB  HB3  sing N N 114 
ASN CG  OD1  doub N N 115 
ASN CG  ND2  sing N N 116 
ASN ND2 HD21 sing N N 117 
ASN ND2 HD22 sing N N 118 
ASN OXT HXT  sing N N 119 
ASP N   CA   sing N N 120 
ASP N   H    sing N N 121 
ASP N   H2   sing N N 122 
ASP CA  C    sing N N 123 
ASP CA  CB   sing N N 124 
ASP CA  HA   sing N N 125 
ASP C   O    doub N N 126 
ASP C   OXT  sing N N 127 
ASP CB  CG   sing N N 128 
ASP CB  HB2  sing N N 129 
ASP CB  HB3  sing N N 130 
ASP CG  OD1  doub N N 131 
ASP CG  OD2  sing N N 132 
ASP OD2 HD2  sing N N 133 
ASP OXT HXT  sing N N 134 
CYS N   CA   sing N N 135 
CYS N   H    sing N N 136 
CYS N   H2   sing N N 137 
CYS CA  C    sing N N 138 
CYS CA  CB   sing N N 139 
CYS CA  HA   sing N N 140 
CYS C   O    doub N N 141 
CYS C   OXT  sing N N 142 
CYS CB  SG   sing N N 143 
CYS CB  HB2  sing N N 144 
CYS CB  HB3  sing N N 145 
CYS SG  HG   sing N N 146 
CYS OXT HXT  sing N N 147 
GLN N   CA   sing N N 148 
GLN N   H    sing N N 149 
GLN N   H2   sing N N 150 
GLN CA  C    sing N N 151 
GLN CA  CB   sing N N 152 
GLN CA  HA   sing N N 153 
GLN C   O    doub N N 154 
GLN C   OXT  sing N N 155 
GLN CB  CG   sing N N 156 
GLN CB  HB2  sing N N 157 
GLN CB  HB3  sing N N 158 
GLN CG  CD   sing N N 159 
GLN CG  HG2  sing N N 160 
GLN CG  HG3  sing N N 161 
GLN CD  OE1  doub N N 162 
GLN CD  NE2  sing N N 163 
GLN NE2 HE21 sing N N 164 
GLN NE2 HE22 sing N N 165 
GLN OXT HXT  sing N N 166 
GLU N   CA   sing N N 167 
GLU N   H    sing N N 168 
GLU N   H2   sing N N 169 
GLU CA  C    sing N N 170 
GLU CA  CB   sing N N 171 
GLU CA  HA   sing N N 172 
GLU C   O    doub N N 173 
GLU C   OXT  sing N N 174 
GLU CB  CG   sing N N 175 
GLU CB  HB2  sing N N 176 
GLU CB  HB3  sing N N 177 
GLU CG  CD   sing N N 178 
GLU CG  HG2  sing N N 179 
GLU CG  HG3  sing N N 180 
GLU CD  OE1  doub N N 181 
GLU CD  OE2  sing N N 182 
GLU OE2 HE2  sing N N 183 
GLU OXT HXT  sing N N 184 
GLY N   CA   sing N N 185 
GLY N   H    sing N N 186 
GLY N   H2   sing N N 187 
GLY CA  C    sing N N 188 
GLY CA  HA2  sing N N 189 
GLY CA  HA3  sing N N 190 
GLY C   O    doub N N 191 
GLY C   OXT  sing N N 192 
GLY OXT HXT  sing N N 193 
GOL C1  O1   sing N N 194 
GOL C1  C2   sing N N 195 
GOL C1  H11  sing N N 196 
GOL C1  H12  sing N N 197 
GOL O1  HO1  sing N N 198 
GOL C2  O2   sing N N 199 
GOL C2  C3   sing N N 200 
GOL C2  H2   sing N N 201 
GOL O2  HO2  sing N N 202 
GOL C3  O3   sing N N 203 
GOL C3  H31  sing N N 204 
GOL C3  H32  sing N N 205 
GOL O3  HO3  sing N N 206 
HIS N   CA   sing N N 207 
HIS N   H    sing N N 208 
HIS N   H2   sing N N 209 
HIS CA  C    sing N N 210 
HIS CA  CB   sing N N 211 
HIS CA  HA   sing N N 212 
HIS C   O    doub N N 213 
HIS C   OXT  sing N N 214 
HIS CB  CG   sing N N 215 
HIS CB  HB2  sing N N 216 
HIS CB  HB3  sing N N 217 
HIS CG  ND1  sing Y N 218 
HIS CG  CD2  doub Y N 219 
HIS ND1 CE1  doub Y N 220 
HIS ND1 HD1  sing N N 221 
HIS CD2 NE2  sing Y N 222 
HIS CD2 HD2  sing N N 223 
HIS CE1 NE2  sing Y N 224 
HIS CE1 HE1  sing N N 225 
HIS NE2 HE2  sing N N 226 
HIS OXT HXT  sing N N 227 
HOH O   H1   sing N N 228 
HOH O   H2   sing N N 229 
ILE N   CA   sing N N 230 
ILE N   H    sing N N 231 
ILE N   H2   sing N N 232 
ILE CA  C    sing N N 233 
ILE CA  CB   sing N N 234 
ILE CA  HA   sing N N 235 
ILE C   O    doub N N 236 
ILE C   OXT  sing N N 237 
ILE CB  CG1  sing N N 238 
ILE CB  CG2  sing N N 239 
ILE CB  HB   sing N N 240 
ILE CG1 CD1  sing N N 241 
ILE CG1 HG12 sing N N 242 
ILE CG1 HG13 sing N N 243 
ILE CG2 HG21 sing N N 244 
ILE CG2 HG22 sing N N 245 
ILE CG2 HG23 sing N N 246 
ILE CD1 HD11 sing N N 247 
ILE CD1 HD12 sing N N 248 
ILE CD1 HD13 sing N N 249 
ILE OXT HXT  sing N N 250 
LEU N   CA   sing N N 251 
LEU N   H    sing N N 252 
LEU N   H2   sing N N 253 
LEU CA  C    sing N N 254 
LEU CA  CB   sing N N 255 
LEU CA  HA   sing N N 256 
LEU C   O    doub N N 257 
LEU C   OXT  sing N N 258 
LEU CB  CG   sing N N 259 
LEU CB  HB2  sing N N 260 
LEU CB  HB3  sing N N 261 
LEU CG  CD1  sing N N 262 
LEU CG  CD2  sing N N 263 
LEU CG  HG   sing N N 264 
LEU CD1 HD11 sing N N 265 
LEU CD1 HD12 sing N N 266 
LEU CD1 HD13 sing N N 267 
LEU CD2 HD21 sing N N 268 
LEU CD2 HD22 sing N N 269 
LEU CD2 HD23 sing N N 270 
LEU OXT HXT  sing N N 271 
LYS N   CA   sing N N 272 
LYS N   H    sing N N 273 
LYS N   H2   sing N N 274 
LYS CA  C    sing N N 275 
LYS CA  CB   sing N N 276 
LYS CA  HA   sing N N 277 
LYS C   O    doub N N 278 
LYS C   OXT  sing N N 279 
LYS CB  CG   sing N N 280 
LYS CB  HB2  sing N N 281 
LYS CB  HB3  sing N N 282 
LYS CG  CD   sing N N 283 
LYS CG  HG2  sing N N 284 
LYS CG  HG3  sing N N 285 
LYS CD  CE   sing N N 286 
LYS CD  HD2  sing N N 287 
LYS CD  HD3  sing N N 288 
LYS CE  NZ   sing N N 289 
LYS CE  HE2  sing N N 290 
LYS CE  HE3  sing N N 291 
LYS NZ  HZ1  sing N N 292 
LYS NZ  HZ2  sing N N 293 
LYS NZ  HZ3  sing N N 294 
LYS OXT HXT  sing N N 295 
MET N   CA   sing N N 296 
MET N   H    sing N N 297 
MET N   H2   sing N N 298 
MET CA  C    sing N N 299 
MET CA  CB   sing N N 300 
MET CA  HA   sing N N 301 
MET C   O    doub N N 302 
MET C   OXT  sing N N 303 
MET CB  CG   sing N N 304 
MET CB  HB2  sing N N 305 
MET CB  HB3  sing N N 306 
MET CG  SD   sing N N 307 
MET CG  HG2  sing N N 308 
MET CG  HG3  sing N N 309 
MET SD  CE   sing N N 310 
MET CE  HE1  sing N N 311 
MET CE  HE2  sing N N 312 
MET CE  HE3  sing N N 313 
MET OXT HXT  sing N N 314 
PHE N   CA   sing N N 315 
PHE N   H    sing N N 316 
PHE N   H2   sing N N 317 
PHE CA  C    sing N N 318 
PHE CA  CB   sing N N 319 
PHE CA  HA   sing N N 320 
PHE C   O    doub N N 321 
PHE C   OXT  sing N N 322 
PHE CB  CG   sing N N 323 
PHE CB  HB2  sing N N 324 
PHE CB  HB3  sing N N 325 
PHE CG  CD1  doub Y N 326 
PHE CG  CD2  sing Y N 327 
PHE CD1 CE1  sing Y N 328 
PHE CD1 HD1  sing N N 329 
PHE CD2 CE2  doub Y N 330 
PHE CD2 HD2  sing N N 331 
PHE CE1 CZ   doub Y N 332 
PHE CE1 HE1  sing N N 333 
PHE CE2 CZ   sing Y N 334 
PHE CE2 HE2  sing N N 335 
PHE CZ  HZ   sing N N 336 
PHE OXT HXT  sing N N 337 
PRO N   CA   sing N N 338 
PRO N   CD   sing N N 339 
PRO N   H    sing N N 340 
PRO CA  C    sing N N 341 
PRO CA  CB   sing N N 342 
PRO CA  HA   sing N N 343 
PRO C   O    doub N N 344 
PRO C   OXT  sing N N 345 
PRO CB  CG   sing N N 346 
PRO CB  HB2  sing N N 347 
PRO CB  HB3  sing N N 348 
PRO CG  CD   sing N N 349 
PRO CG  HG2  sing N N 350 
PRO CG  HG3  sing N N 351 
PRO CD  HD2  sing N N 352 
PRO CD  HD3  sing N N 353 
PRO OXT HXT  sing N N 354 
SER N   CA   sing N N 355 
SER N   H    sing N N 356 
SER N   H2   sing N N 357 
SER CA  C    sing N N 358 
SER CA  CB   sing N N 359 
SER CA  HA   sing N N 360 
SER C   O    doub N N 361 
SER C   OXT  sing N N 362 
SER CB  OG   sing N N 363 
SER CB  HB2  sing N N 364 
SER CB  HB3  sing N N 365 
SER OG  HG   sing N N 366 
SER OXT HXT  sing N N 367 
THR N   CA   sing N N 368 
THR N   H    sing N N 369 
THR N   H2   sing N N 370 
THR CA  C    sing N N 371 
THR CA  CB   sing N N 372 
THR CA  HA   sing N N 373 
THR C   O    doub N N 374 
THR C   OXT  sing N N 375 
THR CB  OG1  sing N N 376 
THR CB  CG2  sing N N 377 
THR CB  HB   sing N N 378 
THR OG1 HG1  sing N N 379 
THR CG2 HG21 sing N N 380 
THR CG2 HG22 sing N N 381 
THR CG2 HG23 sing N N 382 
THR OXT HXT  sing N N 383 
TRP N   CA   sing N N 384 
TRP N   H    sing N N 385 
TRP N   H2   sing N N 386 
TRP CA  C    sing N N 387 
TRP CA  CB   sing N N 388 
TRP CA  HA   sing N N 389 
TRP C   O    doub N N 390 
TRP C   OXT  sing N N 391 
TRP CB  CG   sing N N 392 
TRP CB  HB2  sing N N 393 
TRP CB  HB3  sing N N 394 
TRP CG  CD1  doub Y N 395 
TRP CG  CD2  sing Y N 396 
TRP CD1 NE1  sing Y N 397 
TRP CD1 HD1  sing N N 398 
TRP CD2 CE2  doub Y N 399 
TRP CD2 CE3  sing Y N 400 
TRP NE1 CE2  sing Y N 401 
TRP NE1 HE1  sing N N 402 
TRP CE2 CZ2  sing Y N 403 
TRP CE3 CZ3  doub Y N 404 
TRP CE3 HE3  sing N N 405 
TRP CZ2 CH2  doub Y N 406 
TRP CZ2 HZ2  sing N N 407 
TRP CZ3 CH2  sing Y N 408 
TRP CZ3 HZ3  sing N N 409 
TRP CH2 HH2  sing N N 410 
TRP OXT HXT  sing N N 411 
TYR N   CA   sing N N 412 
TYR N   H    sing N N 413 
TYR N   H2   sing N N 414 
TYR CA  C    sing N N 415 
TYR CA  CB   sing N N 416 
TYR CA  HA   sing N N 417 
TYR C   O    doub N N 418 
TYR C   OXT  sing N N 419 
TYR CB  CG   sing N N 420 
TYR CB  HB2  sing N N 421 
TYR CB  HB3  sing N N 422 
TYR CG  CD1  doub Y N 423 
TYR CG  CD2  sing Y N 424 
TYR CD1 CE1  sing Y N 425 
TYR CD1 HD1  sing N N 426 
TYR CD2 CE2  doub Y N 427 
TYR CD2 HD2  sing N N 428 
TYR CE1 CZ   doub Y N 429 
TYR CE1 HE1  sing N N 430 
TYR CE2 CZ   sing Y N 431 
TYR CE2 HE2  sing N N 432 
TYR CZ  OH   sing N N 433 
TYR OH  HH   sing N N 434 
TYR OXT HXT  sing N N 435 
VAL N   CA   sing N N 436 
VAL N   H    sing N N 437 
VAL N   H2   sing N N 438 
VAL CA  C    sing N N 439 
VAL CA  CB   sing N N 440 
VAL CA  HA   sing N N 441 
VAL C   O    doub N N 442 
VAL C   OXT  sing N N 443 
VAL CB  CG1  sing N N 444 
VAL CB  CG2  sing N N 445 
VAL CB  HB   sing N N 446 
VAL CG1 HG11 sing N N 447 
VAL CG1 HG12 sing N N 448 
VAL CG1 HG13 sing N N 449 
VAL CG2 HG21 sing N N 450 
VAL CG2 HG22 sing N N 451 
VAL CG2 HG23 sing N N 452 
VAL OXT HXT  sing N N 453 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5XYY 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8YD9 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.021841 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011676 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007878 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLU A 1 4   ? -26.50300 41.25754 -37.60218 1.000 78.77803  ? 4   GLU A N   1 
ATOM   2    C CA  . GLU A 1 4   ? -26.48786 41.18670 -39.06129 1.000 77.01331  ? 4   GLU A CA  1 
ATOM   3    C C   . GLU A 1 4   ? -25.20000 40.56055 -39.58271 1.000 65.70426  ? 4   GLU A C   1 
ATOM   4    O O   . GLU A 1 4   ? -24.10473 40.89432 -39.13647 1.000 65.39182  ? 4   GLU A O   1 
ATOM   5    C CB  . GLU A 1 4   ? -26.68148 42.57743 -39.67112 1.000 82.68456  ? 4   GLU A CB  1 
ATOM   6    C CG  . GLU A 1 4   ? -28.01454 43.20544 -39.31419 1.000 90.21239  ? 4   GLU A CG  1 
ATOM   7    C CD  . GLU A 1 4   ? -29.11213 42.79947 -40.27948 1.000 96.91685  ? 4   GLU A CD  1 
ATOM   8    O OE1 . GLU A 1 4   ? -28.92420 42.98436 -41.50217 1.000 99.74263  ? 4   GLU A OE1 1 
ATOM   9    O OE2 . GLU A 1 4   ? -30.15348 42.28130 -39.81952 1.000 97.46318  ? 4   GLU A OE2 1 
ATOM   10   N N   . ARG A 1 5   ? -25.35087 39.64378 -40.52642 1.000 57.52440  ? 5   ARG A N   1 
ATOM   11   C CA  . ARG A 1 5   ? -24.19981 38.99156 -41.12040 1.000 52.76565  ? 5   ARG A CA  1 
ATOM   12   C C   . ARG A 1 5   ? -23.29801 40.02282 -41.78609 1.000 47.39395  ? 5   ARG A C   1 
ATOM   13   O O   . ARG A 1 5   ? -23.77304 40.81847 -42.60683 1.000 48.14813  ? 5   ARG A O   1 
ATOM   14   C CB  . ARG A 1 5   ? -24.64700 37.94628 -42.14275 1.000 57.86579  ? 5   ARG A CB  1 
ATOM   15   C CG  . ARG A 1 5   ? -23.55555 36.95919 -42.57235 1.000 57.74290  ? 5   ARG A CG  1 
ATOM   16   C CD  . ARG A 1 5   ? -24.15222 35.76129 -43.30888 1.000 55.01366  ? 5   ARG A CD  1 
ATOM   17   N NE  . ARG A 1 5   ? -23.14519 34.95378 -43.98559 1.000 51.82970  ? 5   ARG A NE  1 
ATOM   18   C CZ  . ARG A 1 5   ? -22.54860 35.30414 -45.11685 1.000 56.41593  ? 5   ARG A CZ  1 
ATOM   19   N NH1 . ARG A 1 5   ? -22.84812 36.44022 -45.73465 1.000 58.80292  ? 5   ARG A NH1 1 
ATOM   20   N NH2 . ARG A 1 5   ? -21.64432 34.48766 -45.65341 1.000 55.30472  ? 5   ARG A NH2 1 
ATOM   21   N N   . PRO A 1 6   ? -22.01061 40.05101 -41.46706 1.000 44.36996  ? 6   PRO A N   1 
ATOM   22   C CA  . PRO A 1 6   ? -21.08233 40.83225 -42.28279 1.000 41.27393  ? 6   PRO A CA  1 
ATOM   23   C C   . PRO A 1 6   ? -20.95066 40.23528 -43.67323 1.000 39.40189  ? 6   PRO A C   1 
ATOM   24   O O   . PRO A 1 6   ? -21.38197 39.11010 -43.94872 1.000 38.49547  ? 6   PRO A O   1 
ATOM   25   C CB  . PRO A 1 6   ? -19.76612 40.74203 -41.49913 1.000 40.56524  ? 6   PRO A CB  1 
ATOM   26   C CG  . PRO A 1 6   ? -19.84646 39.40637 -40.83796 1.000 41.78605  ? 6   PRO A CG  1 
ATOM   27   C CD  . PRO A 1 6   ? -21.30419 39.30814 -40.40451 1.000 42.61730  ? 6   PRO A CD  1 
ATOM   28   N N   . THR A 1 7   ? -20.37576 41.03859 -44.56328 1.000 36.98581  ? 7   THR A N   1 
ATOM   29   C CA  . THR A 1 7   ? -19.98450 40.57497 -45.88231 1.000 36.25783  ? 7   THR A CA  1 
ATOM   30   C C   . THR A 1 7   ? -18.64418 39.85800 -45.78890 1.000 34.95545  ? 7   THR A C   1 
ATOM   31   O O   . THR A 1 7   ? -17.71844 40.34359 -45.13379 1.000 35.69742  ? 7   THR A O   1 
ATOM   32   C CB  . THR A 1 7   ? -19.88981 41.75195 -46.85073 1.000 36.85191  ? 7   THR A CB  1 
ATOM   33   O OG1 . THR A 1 7   ? -21.18928 42.33400 -47.01014 1.000 39.17115  ? 7   THR A OG1 1 
ATOM   34   C CG2 . THR A 1 7   ? -19.34674 41.29866 -48.22144 1.000 37.83325  ? 7   THR A CG2 1 
ATOM   35   N N   . PHE A 1 8   ? -18.55992 38.69114 -46.41704 1.000 33.81759  ? 8   PHE A N   1 
ATOM   36   C CA  . PHE A 1 8   ? -17.35505 37.87869 -46.47488 1.000 35.58129  ? 8   PHE A CA  1 
ATOM   37   C C   . PHE A 1 8   ? -16.72491 38.01003 -47.85790 1.000 39.01551  ? 8   PHE A C   1 
ATOM   38   O O   . PHE A 1 8   ? -17.41361 38.26931 -48.85356 1.000 41.09174  ? 8   PHE A O   1 
ATOM   39   C CB  . PHE A 1 8   ? -17.67592 36.39922 -46.22285 1.000 37.89247  ? 8   PHE A CB  1 
ATOM   40   C CG  . PHE A 1 8   ? -18.04695 36.05811 -44.80432 1.000 36.06097  ? 8   PHE A CG  1 
ATOM   41   C CD1 . PHE A 1 8   ? -19.23202 36.50364 -44.24619 1.000 38.42941  ? 8   PHE A CD1 1 
ATOM   42   C CD2 . PHE A 1 8   ? -17.23010 35.22215 -44.04634 1.000 32.53149  ? 8   PHE A CD2 1 
ATOM   43   C CE1 . PHE A 1 8   ? -19.57562 36.16179 -42.93768 1.000 35.96158  ? 8   PHE A CE1 1 
ATOM   44   C CE2 . PHE A 1 8   ? -17.56507 34.88436 -42.75365 1.000 33.91681  ? 8   PHE A CE2 1 
ATOM   45   C CZ  . PHE A 1 8   ? -18.74422 35.35648 -42.19331 1.000 34.82395  ? 8   PHE A CZ  1 
ATOM   46   N N   . TYR A 1 9   ? -15.40572 37.82092 -47.91908 1.000 37.25196  ? 9   TYR A N   1 
ATOM   47   C CA  . TYR A 1 9   ? -14.68833 37.74278 -49.18681 1.000 36.20009  ? 9   TYR A CA  1 
ATOM   48   C C   . TYR A 1 9   ? -13.73099 36.55831 -49.13623 1.000 37.46946  ? 9   TYR A C   1 
ATOM   49   O O   . TYR A 1 9   ? -13.37842 36.07028 -48.05788 1.000 38.77841  ? 9   TYR A O   1 
ATOM   50   C CB  . TYR A 1 9   ? -13.95321 39.05983 -49.51199 1.000 34.08845  ? 9   TYR A CB  1 
ATOM   51   C CG  . TYR A 1 9   ? -12.69332 39.31736 -48.69524 1.000 36.19401  ? 9   TYR A CG  1 
ATOM   52   C CD1 . TYR A 1 9   ? -12.78093 39.77302 -47.37892 1.000 34.80533  ? 9   TYR A CD1 1 
ATOM   53   C CD2 . TYR A 1 9   ? -11.42575 39.16994 -49.25190 1.000 40.19147  ? 9   TYR A CD2 1 
ATOM   54   C CE1 . TYR A 1 9   ? -11.64795 40.03283 -46.63247 1.000 35.08664  ? 9   TYR A CE1 1 
ATOM   55   C CE2 . TYR A 1 9   ? -10.27359 39.43885 -48.50858 1.000 37.77450  ? 9   TYR A CE2 1 
ATOM   56   C CZ  . TYR A 1 9   ? -10.39319 39.86024 -47.19643 1.000 37.82768  ? 9   TYR A CZ  1 
ATOM   57   O OH  . TYR A 1 9   ? -9.26704  40.13105 -46.43655 1.000 36.81357  ? 9   TYR A OH  1 
ATOM   58   N N   . ARG A 1 10  ? -13.32058 36.09027 -50.31807 1.000 41.89150  ? 10  ARG A N   1 
ATOM   59   C CA  . ARG A 1 10  ? -12.58641 34.83672 -50.46800 1.000 46.80646  ? 10  ARG A CA  1 
ATOM   60   C C   . ARG A 1 10  ? -11.15544 35.05588 -50.94254 1.000 48.45868  ? 10  ARG A C   1 
ATOM   61   O O   . ARG A 1 10  ? -10.86325 35.99923 -51.67846 1.000 55.87316  ? 10  ARG A O   1 
ATOM   62   C CB  . ARG A 1 10  ? -13.27727 33.91102 -51.46793 1.000 56.10378  ? 10  ARG A CB  1 
ATOM   63   C CG  . ARG A 1 10  ? -14.59861 33.35477 -51.00921 1.000 65.06466  ? 10  ARG A CG  1 
ATOM   64   C CD  . ARG A 1 10  ? -15.29194 32.68012 -52.16796 1.000 72.80094  ? 10  ARG A CD  1 
ATOM   65   N NE  . ARG A 1 10  ? -15.30010 31.23656 -51.98532 1.000 79.57391  ? 10  ARG A NE  1 
ATOM   66   C CZ  . ARG A 1 10  ? -14.72609 30.37979 -52.81780 1.000 85.23423  ? 10  ARG A CZ  1 
ATOM   67   N NH1 . ARG A 1 10  ? -14.09578 30.79169 -53.90718 1.000 88.00842  ? 10  ARG A NH1 1 
ATOM   68   N NH2 . ARG A 1 10  ? -14.77625 29.07850 -52.54571 1.000 85.88669  ? 10  ARG A NH2 1 
ATOM   69   N N   . GLN A 1 11  ? -10.27903 34.12477 -50.57501 1.000 48.73056  ? 11  GLN A N   1 
ATOM   70   C CA  . GLN A 1 11  ? -8.85788  34.24195 -50.87977 1.000 52.92358  ? 11  GLN A CA  1 
ATOM   71   C C   . GLN A 1 11  ? -8.21703  32.85880 -50.79804 1.000 54.88772  ? 11  GLN A C   1 
ATOM   72   O O   . GLN A 1 11  ? -8.66369  32.00890 -50.02287 1.000 52.81572  ? 11  GLN A O   1 
ATOM   73   C CB  . GLN A 1 11  ? -8.19609  35.22536 -49.90849 1.000 53.76539  ? 11  GLN A CB  1 
ATOM   74   C CG  . GLN A 1 11  ? -7.20167  36.17636 -50.51530 1.000 63.58595  ? 11  GLN A CG  1 
ATOM   75   C CD  . GLN A 1 11  ? -6.40422  36.89839 -49.45731 1.000 69.97807  ? 11  GLN A CD  1 
ATOM   76   O OE1 . GLN A 1 11  ? -5.18419  37.02145 -49.55276 1.000 71.74059  ? 11  GLN A OE1 1 
ATOM   77   N NE2 . GLN A 1 11  ? -7.09719  37.38875 -48.43443 1.000 72.56114  ? 11  GLN A NE2 1 
ATOM   78   N N   . GLU A 1 12  ? -7.15941  32.64890 -51.59299 1.000 59.39491  ? 12  GLU A N   1 
ATOM   79   C CA  . GLU A 1 12  ? -6.50306  31.34740 -51.72487 1.000 68.51905  ? 12  GLU A CA  1 
ATOM   80   C C   . GLU A 1 12  ? -5.45998  31.06825 -50.64224 1.000 75.23088  ? 12  GLU A C   1 
ATOM   81   O O   . GLU A 1 12  ? -5.45086  29.98322 -50.06395 1.000 82.22976  ? 12  GLU A O   1 
ATOM   82   C CB  . GLU A 1 12  ? -5.84211  31.21498 -53.09532 1.000 73.97853  ? 12  GLU A CB  1 
ATOM   83   C CG  . GLU A 1 12  ? -5.17896  29.85769 -53.30757 1.000 80.13198  ? 12  GLU A CG  1 
ATOM   84   C CD  . GLU A 1 12  ? -6.17201  28.77004 -53.67752 1.000 83.90467  ? 12  GLU A CD  1 
ATOM   85   O OE1 . GLU A 1 12  ? -6.86229  28.91527 -54.70881 1.000 82.23604  ? 12  GLU A OE1 1 
ATOM   86   O OE2 . GLU A 1 12  ? -6.26180  27.76672 -52.94060 1.000 88.62158  ? 12  GLU A OE2 1 
ATOM   87   N N   . LEU A 1 13  ? -4.52865  31.98062 -50.39902 1.000 76.87406  ? 13  LEU A N   1 
ATOM   88   C CA  . LEU A 1 13  ? -3.67383  31.89476 -49.19814 1.000 82.78594  ? 13  LEU A CA  1 
ATOM   89   C C   . LEU A 1 13  ? -2.89119  30.58082 -49.19382 1.000 93.47596  ? 13  LEU A C   1 
ATOM   90   O O   . LEU A 1 13  ? -2.23316  30.27146 -50.20047 1.000 98.85146  ? 13  LEU A O   1 
ATOM   91   C CB  . LEU A 1 13  ? -4.56676  32.12324 -47.98972 1.000 79.46579  ? 13  LEU A CB  1 
ATOM   92   C CG  . LEU A 1 13  ? -4.38909  33.53097 -47.45418 1.000 77.40055  ? 13  LEU A CG  1 
ATOM   93   C CD1 . LEU A 1 13  ? -2.97822  33.68851 -46.95486 1.000 77.64235  ? 13  LEU A CD1 1 
ATOM   94   C CD2 . LEU A 1 13  ? -4.64001  34.47835 -48.59614 1.000 77.90843  ? 13  LEU A CD2 1 
ATOM   95   N N   . ASN A 1 14  ? -2.90744  29.80899 -48.09806 1.000 95.77299  ? 14  ASN A N   1 
ATOM   96   C CA  . ASN A 1 14  ? -2.13823  28.57554 -47.94826 1.000 96.93967  ? 14  ASN A CA  1 
ATOM   97   C C   . ASN A 1 14  ? -2.23362  27.68758 -49.17682 1.000 92.50379  ? 14  ASN A C   1 
ATOM   98   O O   . ASN A 1 14  ? -1.64396  27.95937 -50.22720 1.000 88.31078  ? 14  ASN A O   1 
ATOM   99   C CB  . ASN A 1 14  ? -2.63664  27.75330 -46.74953 1.000 100.87529 ? 14  ASN A CB  1 
ATOM   100  C CG  . ASN A 1 14  ? -2.19238  28.30870 -45.41284 1.000 103.06386 ? 14  ASN A CG  1 
ATOM   101  O OD1 . ASN A 1 14  ? -2.58321  29.40545 -45.01754 1.000 100.24800 ? 14  ASN A OD1 1 
ATOM   102  N ND2 . ASN A 1 14  ? -1.37384  27.54172 -44.70147 1.000 106.93441 ? 14  ASN A ND2 1 
ATOM   103  N N   . LYS A 1 15  ? -2.95456  26.58765 -49.00436 1.000 87.79483  ? 15  LYS A N   1 
ATOM   104  C CA  . LYS A 1 15  ? -3.41222  25.73513 -50.08092 1.000 81.83881  ? 15  LYS A CA  1 
ATOM   105  C C   . LYS A 1 15  ? -4.92979  25.70710 -50.10333 1.000 74.38036  ? 15  LYS A C   1 
ATOM   106  O O   . LYS A 1 15  ? -5.51808  25.02919 -50.95368 1.000 72.99815  ? 15  LYS A O   1 
ATOM   107  C CB  . LYS A 1 15  ? -2.87467  24.31579 -49.87777 1.000 86.88236  ? 15  LYS A CB  1 
ATOM   108  C CG  . LYS A 1 15  ? -1.37795  24.27664 -49.62387 1.000 91.71554  ? 15  LYS A CG  1 
ATOM   109  C CD  . LYS A 1 15  ? -0.62166  23.44181 -50.63432 1.000 95.20497  ? 15  LYS A CD  1 
ATOM   110  C CE  . LYS A 1 15  ? 0.81582   23.92303 -50.74209 1.000 97.82148  ? 15  LYS A CE  1 
ATOM   111  N NZ  . LYS A 1 15  ? 1.75051   23.02048 -50.01252 1.000 99.09011  ? 15  LYS A NZ  1 
ATOM   112  N N   A THR A 1 16  ? -5.58267  26.41097 -49.18245 0.500 69.65137  ? 16  THR A N   1 
ATOM   113  N N   B THR A 1 16  ? -5.57227  26.45678 -49.20868 0.500 70.14100  ? 16  THR A N   1 
ATOM   114  C CA  A THR A 1 16  ? -7.01481  26.30100 -48.96853 0.500 65.92323  ? 16  THR A CA  1 
ATOM   115  C CA  B THR A 1 16  ? -6.98816  26.34064 -48.90782 0.500 66.85023  ? 16  THR A CA  1 
ATOM   116  C C   A THR A 1 16  ? -7.67791  27.66342 -49.11149 0.500 62.02413  ? 16  THR A C   1 
ATOM   117  C C   B THR A 1 16  ? -7.67713  27.68104 -49.11716 0.500 62.46338  ? 16  THR A C   1 
ATOM   118  O O   A THR A 1 16  ? -7.04010  28.70752 -48.97386 0.500 60.42209  ? 16  THR A O   1 
ATOM   119  O O   B THR A 1 16  ? -7.05062  28.73654 -49.02386 0.500 60.44129  ? 16  THR A O   1 
ATOM   120  C CB  A THR A 1 16  ? -7.32268  25.71411 -47.58287 0.500 67.91219  ? 16  THR A CB  1 
ATOM   121  C CB  B THR A 1 16  ? -7.19440  25.88306 -47.45908 0.500 69.77747  ? 16  THR A CB  1 
ATOM   122  O OG1 A THR A 1 16  ? -8.63465  25.13551 -47.58246 0.500 65.99985  ? 16  THR A OG1 1 
ATOM   123  O OG1 B THR A 1 16  ? -8.11343  26.76524 -46.80399 0.500 71.62872  ? 16  THR A OG1 1 
ATOM   124  C CG2 A THR A 1 16  ? -7.23451  26.79614 -46.51005 0.500 69.07081  ? 16  THR A CG2 1 
ATOM   125  C CG2 B THR A 1 16  ? -5.86489  25.90656 -46.70717 0.500 68.24821  ? 16  THR A CG2 1 
ATOM   126  N N   . ILE A 1 17  ? -8.97770  27.63473 -49.37533 1.000 59.17286  ? 17  ILE A N   1 
ATOM   127  C CA  . ILE A 1 17  ? -9.74759  28.85067 -49.59428 1.000 55.22023  ? 17  ILE A CA  1 
ATOM   128  C C   . ILE A 1 17  ? -10.11952 29.44654 -48.24253 1.000 50.93783  ? 17  ILE A C   1 
ATOM   129  O O   . ILE A 1 17  ? -10.62502 28.74204 -47.36267 1.000 51.86047  ? 17  ILE A O   1 
ATOM   130  C CB  . ILE A 1 17  ? -10.99916 28.54598 -50.43067 1.000 58.87081  ? 17  ILE A CB  1 
ATOM   131  C CG1 . ILE A 1 17  ? -10.60035 28.15449 -51.85719 1.000 57.10567  ? 17  ILE A CG1 1 
ATOM   132  C CG2 . ILE A 1 17  ? -11.94361 29.74121 -50.43198 1.000 60.29000  ? 17  ILE A CG2 1 
ATOM   133  C CD1 . ILE A 1 17  ? -9.91672  29.24558 -52.61594 1.000 57.45744  ? 17  ILE A CD1 1 
ATOM   134  N N   . TRP A 1 18  ? -9.86834  30.74412 -48.06501 1.000 44.28264  ? 18  TRP A N   1 
ATOM   135  C CA  . TRP A 1 18  ? -10.21667 31.44331 -46.83412 1.000 40.00425  ? 18  TRP A CA  1 
ATOM   136  C C   . TRP A 1 18  ? -11.37191 32.39588 -47.10512 1.000 37.48413  ? 18  TRP A C   1 
ATOM   137  O O   . TRP A 1 18  ? -11.29950 33.20910 -48.02982 1.000 41.56632  ? 18  TRP A O   1 
ATOM   138  C CB  . TRP A 1 18  ? -9.01876  32.21771 -46.28087 1.000 39.79433  ? 18  TRP A CB  1 
ATOM   139  C CG  . TRP A 1 18  ? -7.95869  31.34468 -45.68207 1.000 46.65246  ? 18  TRP A CG  1 
ATOM   140  C CD1 . TRP A 1 18  ? -7.21084  30.39483 -46.32737 1.000 54.45860  ? 18  TRP A CD1 1 
ATOM   141  C CD2 . TRP A 1 18  ? -7.52833  31.32850 -44.31245 1.000 43.91626  ? 18  TRP A CD2 1 
ATOM   142  N NE1 . TRP A 1 18  ? -6.34356  29.79492 -45.44165 1.000 52.85022  ? 18  TRP A NE1 1 
ATOM   143  C CE2 . TRP A 1 18  ? -6.52004  30.34955 -44.19995 1.000 48.29512  ? 18  TRP A CE2 1 
ATOM   144  C CE3 . TRP A 1 18  ? -7.89671  32.04927 -43.17229 1.000 39.93113  ? 18  TRP A CE3 1 
ATOM   145  C CZ2 . TRP A 1 18  ? -5.87463  30.07421 -42.98987 1.000 42.05154  ? 18  TRP A CZ2 1 
ATOM   146  C CZ3 . TRP A 1 18  ? -7.25808  31.76710 -41.96858 1.000 40.67550  ? 18  TRP A CZ3 1 
ATOM   147  C CH2 . TRP A 1 18  ? -6.25539  30.78863 -41.89172 1.000 39.02374  ? 18  TRP A CH2 1 
ATOM   148  N N   . GLU A 1 19  ? -12.42712 32.30611 -46.29803 1.000 33.66953  ? 19  GLU A N   1 
ATOM   149  C CA  . GLU A 1 19  ? -13.60501 33.15978 -46.43826 1.000 35.55606  ? 19  GLU A CA  1 
ATOM   150  C C   . GLU A 1 19  ? -13.80781 33.90617 -45.12550 1.000 32.74224  ? 19  GLU A C   1 
ATOM   151  O O   . GLU A 1 19  ? -14.17572 33.29031 -44.11993 1.000 33.31959  ? 19  GLU A O   1 
ATOM   152  C CB  . GLU A 1 19  ? -14.84182 32.33395 -46.79827 1.000 41.07407  ? 19  GLU A CB  1 
ATOM   153  C CG  . GLU A 1 19  ? -16.04688 33.16740 -47.20017 1.000 51.43548  ? 19  GLU A CG  1 
ATOM   154  C CD  . GLU A 1 19  ? -16.92450 32.49575 -48.25051 1.000 61.26268  ? 19  GLU A CD  1 
ATOM   155  O OE1 . GLU A 1 19  ? -16.72565 31.28757 -48.52629 1.000 64.78270  ? 19  GLU A OE1 1 
ATOM   156  O OE2 . GLU A 1 19  ? -17.81481 33.18531 -48.80130 1.000 59.21050  ? 19  GLU A OE2 1 
ATOM   157  N N   . VAL A 1 20  ? -13.57020 35.21921 -45.11736 1.000 29.76057  ? 20  VAL A N   1 
ATOM   158  C CA  . VAL A 1 20  ? -13.54863 35.95601 -43.84480 1.000 28.89181  ? 20  VAL A CA  1 
ATOM   159  C C   . VAL A 1 20  ? -14.27753 37.27766 -44.00356 1.000 28.91529  ? 20  VAL A C   1 
ATOM   160  O O   . VAL A 1 20  ? -14.37698 37.82992 -45.10629 1.000 34.74577  ? 20  VAL A O   1 
ATOM   161  C CB  . VAL A 1 20  ? -12.10413 36.20107 -43.36299 1.000 30.39201  ? 20  VAL A CB  1 
ATOM   162  C CG1 . VAL A 1 20  ? -11.31643 34.87299 -43.39345 1.000 29.07997  ? 20  VAL A CG1 1 
ATOM   163  C CG2 . VAL A 1 20  ? -11.41095 37.26323 -44.24447 1.000 35.11798  ? 20  VAL A CG2 1 
ATOM   164  N N   . PRO A 1 21  ? -14.83101 37.80381 -42.90095 1.000 30.84556  ? 21  PRO A N   1 
ATOM   165  C CA  . PRO A 1 21  ? -15.47537 39.12853 -42.96070 1.000 29.26670  ? 21  PRO A CA  1 
ATOM   166  C C   . PRO A 1 21  ? -14.49860 40.19824 -43.42124 1.000 30.33201  ? 21  PRO A C   1 
ATOM   167  O O   . PRO A 1 21  ? -13.31105 40.14640 -43.10889 1.000 31.26139  ? 21  PRO A O   1 
ATOM   168  C CB  . PRO A 1 21  ? -15.94769 39.37768 -41.52264 1.000 29.11830  ? 21  PRO A CB  1 
ATOM   169  C CG  . PRO A 1 21  ? -15.96199 38.04374 -40.87573 1.000 30.91820  ? 21  PRO A CG  1 
ATOM   170  C CD  . PRO A 1 21  ? -14.92646 37.18898 -41.57436 1.000 31.97266  ? 21  PRO A CD  1 
ATOM   171  N N   A GLU A 1 22  ? -15.01582 41.18961 -44.15661 0.300 31.96674  ? 22  GLU A N   1 
ATOM   172  N N   B GLU A 1 22  ? -15.03455 41.18837 -44.15323 0.700 32.90749  ? 22  GLU A N   1 
ATOM   173  C CA  A GLU A 1 22  ? -14.14837 42.21143 -44.73798 0.300 30.98061  ? 22  GLU A CA  1 
ATOM   174  C CA  B GLU A 1 22  ? -14.20800 42.24853 -44.72183 0.700 29.66503  ? 22  GLU A CA  1 
ATOM   175  C C   A GLU A 1 22  ? -13.42262 43.05121 -43.69232 0.300 31.32007  ? 22  GLU A C   1 
ATOM   176  C C   B GLU A 1 22  ? -13.38360 42.97375 -43.67229 0.700 32.01285  ? 22  GLU A C   1 
ATOM   177  O O   A GLU A 1 22  ? -12.46846 43.75379 -44.04562 0.300 31.63990  ? 22  GLU A O   1 
ATOM   178  O O   B GLU A 1 22  ? -12.32212 43.51272 -43.99640 0.700 33.76222  ? 22  GLU A O   1 
ATOM   179  C CB  A GLU A 1 22  ? -14.94246 43.13204 -45.67190 0.300 32.70625  ? 22  GLU A CB  1 
ATOM   180  C CB  B GLU A 1 22  ? -15.06678 43.27459 -45.47615 0.700 31.05756  ? 22  GLU A CB  1 
ATOM   181  C CG  A GLU A 1 22  ? -16.38557 43.36285 -45.27007 0.300 31.86733  ? 22  GLU A CG  1 
ATOM   182  C CG  B GLU A 1 22  ? -16.01289 42.72165 -46.53207 0.700 30.96102  ? 22  GLU A CG  1 
ATOM   183  C CD  A GLU A 1 22  ? -17.17680 44.11675 -46.32858 0.300 32.05034  ? 22  GLU A CD  1 
ATOM   184  C CD  B GLU A 1 22  ? -16.83242 43.83362 -47.17536 0.700 36.80251  ? 22  GLU A CD  1 
ATOM   185  O OE1 A GLU A 1 22  ? -16.78599 44.08758 -47.51565 0.300 37.99821  ? 22  GLU A OE1 1 
ATOM   186  O OE1 B GLU A 1 22  ? -17.75393 44.34248 -46.50757 0.700 35.62012  ? 22  GLU A OE1 1 
ATOM   187  O OE2 A GLU A 1 22  ? -18.19681 44.74271 -45.96926 0.300 31.29786  ? 22  GLU A OE2 1 
ATOM   188  O OE2 B GLU A 1 22  ? -16.53688 44.22901 -48.33393 0.700 38.05139  ? 22  GLU A OE2 1 
ATOM   189  N N   . ARG A 1 23  ? -13.84243 43.00655 -42.42509 1.000 31.87117  ? 23  ARG A N   1 
ATOM   190  C CA  . ARG A 1 23  ? -13.08588 43.69835 -41.38567 1.000 31.93077  ? 23  ARG A CA  1 
ATOM   191  C C   . ARG A 1 23  ? -11.64838 43.19661 -41.30781 1.000 30.53995  ? 23  ARG A C   1 
ATOM   192  O O   . ARG A 1 23  ? -10.73856 43.96551 -40.96706 1.000 32.09597  ? 23  ARG A O   1 
ATOM   193  C CB  . ARG A 1 23  ? -13.82154 43.55510 -40.05675 1.000 32.70289  ? 23  ARG A CB  1 
ATOM   194  C CG  . ARG A 1 23  ? -13.62215 42.24052 -39.36666 1.000 32.70610  ? 23  ARG A CG  1 
ATOM   195  C CD  . ARG A 1 23  ? -14.54191 42.16838 -38.17772 1.000 31.85128  ? 23  ARG A CD  1 
ATOM   196  N NE  . ARG A 1 23  ? -13.88204 42.59382 -36.94948 1.000 31.37119  ? 23  ARG A NE  1 
ATOM   197  C CZ  . ARG A 1 23  ? -14.44381 42.54800 -35.75123 1.000 35.76036  ? 23  ARG A CZ  1 
ATOM   198  N NH1 . ARG A 1 23  ? -15.68472 42.10145 -35.58389 1.000 36.80259  ? 23  ARG A NH1 1 
ATOM   199  N NH2 . ARG A 1 23  ? -13.75940 42.98975 -34.69720 1.000 37.49457  ? 23  ARG A NH2 1 
ATOM   200  N N   . TYR A 1 24  ? -11.41108 41.92978 -41.64833 1.000 28.97907  ? 24  TYR A N   1 
ATOM   201  C CA  . TYR A 1 24  ? -10.07755 41.35414 -41.54149 1.000 27.62054  ? 24  TYR A CA  1 
ATOM   202  C C   . TYR A 1 24  ? -9.33840  41.54408 -42.86310 1.000 29.49464  ? 24  TYR A C   1 
ATOM   203  O O   . TYR A 1 24  ? -9.80174  41.08605 -43.91210 1.000 34.02336  ? 24  TYR A O   1 
ATOM   204  C CB  . TYR A 1 24  ? -10.17002 39.87762 -41.16730 1.000 27.83756  ? 24  TYR A CB  1 
ATOM   205  C CG  . TYR A 1 24  ? -10.84132 39.67446 -39.82806 1.000 30.07124  ? 24  TYR A CG  1 
ATOM   206  C CD1 . TYR A 1 24  ? -10.22192 40.10535 -38.66251 1.000 29.25671  ? 24  TYR A CD1 1 
ATOM   207  C CD2 . TYR A 1 24  ? -12.09415 39.05831 -39.72532 1.000 28.41670  ? 24  TYR A CD2 1 
ATOM   208  C CE1 . TYR A 1 24  ? -10.81135 39.96646 -37.45218 1.000 27.85105  ? 24  TYR A CE1 1 
ATOM   209  C CE2 . TYR A 1 24  ? -12.70851 38.90255 -38.49411 1.000 29.01188  ? 24  TYR A CE2 1 
ATOM   210  C CZ  . TYR A 1 24  ? -12.04816 39.34902 -37.35476 1.000 30.05207  ? 24  TYR A CZ  1 
ATOM   211  O OH  . TYR A 1 24  ? -12.62102 39.23121 -36.13600 1.000 29.49515  ? 24  TYR A OH  1 
ATOM   212  N N   . GLN A 1 25  ? -8.20701  42.23892 -42.81689 1.000 30.59373  ? 25  GLN A N   1 
ATOM   213  C CA  . GLN A 1 25  ? -7.45779  42.60147 -44.01443 1.000 35.55236  ? 25  GLN A CA  1 
ATOM   214  C C   . GLN A 1 25  ? -6.00707  42.13227 -43.91581 1.000 38.01321  ? 25  GLN A C   1 
ATOM   215  O O   . GLN A 1 25  ? -5.50332  41.81468 -42.83224 1.000 37.46833  ? 25  GLN A O   1 
ATOM   216  C CB  . GLN A 1 25  ? -7.51495  44.11679 -44.24553 1.000 32.84740  ? 25  GLN A CB  1 
ATOM   217  C CG  . GLN A 1 25  ? -8.91662  44.62215 -44.64669 1.000 32.79614  ? 25  GLN A CG  1 
ATOM   218  C CD  . GLN A 1 25  ? -9.28593  44.19363 -46.05844 1.000 35.20153  ? 25  GLN A CD  1 
ATOM   219  O OE1 . GLN A 1 25  ? -8.45824  44.25313 -46.96544 1.000 38.10119  ? 25  GLN A OE1 1 
ATOM   220  N NE2 . GLN A 1 25  ? -10.53241 43.76278 -46.24788 1.000 33.38134  ? 25  GLN A NE2 1 
ATOM   221  N N   . ASN A 1 26  ? -5.34512  42.07719 -45.07870 1.000 39.84714  ? 26  ASN A N   1 
ATOM   222  C CA  . ASN A 1 26  ? -3.90925  41.78288 -45.17075 1.000 42.09833  ? 26  ASN A CA  1 
ATOM   223  C C   . ASN A 1 26  ? -3.55837  40.42833 -44.55558 1.000 45.33056  ? 26  ASN A C   1 
ATOM   224  O O   . ASN A 1 26  ? -2.60605  40.29789 -43.78443 1.000 48.67438  ? 26  ASN A O   1 
ATOM   225  C CB  . ASN A 1 26  ? -3.07605  42.89740 -44.53413 1.000 48.32879  ? 26  ASN A CB  1 
ATOM   226  C CG  . ASN A 1 26  ? -3.46995  44.29604 -45.01873 1.000 60.02290  ? 26  ASN A CG  1 
ATOM   227  O OD1 . ASN A 1 26  ? -3.46825  45.25202 -44.23964 1.000 64.22783  ? 26  ASN A OD1 1 
ATOM   228  N ND2 . ASN A 1 26  ? -3.72575  44.43352 -46.32942 1.000 59.18203  ? 26  ASN A ND2 1 
ATOM   229  N N   . LEU A 1 27  ? -4.32373  39.40344 -44.91921 1.000 41.21478  ? 27  LEU A N   1 
ATOM   230  C CA  . LEU A 1 27  ? -4.01054  38.05452 -44.46816 1.000 40.99369  ? 27  LEU A CA  1 
ATOM   231  C C   . LEU A 1 27  ? -2.67801  37.59072 -45.03429 1.000 41.49898  ? 27  LEU A C   1 
ATOM   232  O O   . LEU A 1 27  ? -2.43067  37.69788 -46.23612 1.000 47.25555  ? 27  LEU A O   1 
ATOM   233  C CB  . LEU A 1 27  ? -5.11160  37.07883 -44.87180 1.000 38.79029  ? 27  LEU A CB  1 
ATOM   234  C CG  . LEU A 1 27  ? -6.33499  37.08149 -43.95636 1.000 43.17466  ? 27  LEU A CG  1 
ATOM   235  C CD1 . LEU A 1 27  ? -7.10378  38.38422 -44.08369 1.000 44.37912  ? 27  LEU A CD1 1 
ATOM   236  C CD2 . LEU A 1 27  ? -7.21975  35.89471 -44.29754 1.000 45.19980  ? 27  LEU A CD2 1 
ATOM   237  N N   A SER A 1 28  ? -1.80643  37.08620 -44.15975 0.480 43.94085  ? 28  SER A N   1 
ATOM   238  N N   B SER A 1 28  ? -1.83261  37.05552 -44.16176 0.520 43.69771  ? 28  SER A N   1 
ATOM   239  C CA  A SER A 1 28  ? -0.54496  36.49069 -44.58639 0.480 43.86220  ? 28  SER A CA  1 
ATOM   240  C CA  B SER A 1 28  ? -0.53675  36.51008 -44.54248 0.520 43.77241  ? 28  SER A CA  1 
ATOM   241  C C   A SER A 1 28  ? -0.33713  35.22173 -43.76564 0.480 44.52743  ? 28  SER A C   1 
ATOM   242  C C   B SER A 1 28  ? -0.29655  35.22665 -43.75115 0.520 44.90979  ? 28  SER A C   1 
ATOM   243  O O   A SER A 1 28  ? -0.40976  35.26764 -42.52377 0.480 43.18391  ? 28  SER A O   1 
ATOM   244  O O   B SER A 1 28  ? -0.31658  35.25109 -42.51342 0.520 43.52381  ? 28  SER A O   1 
ATOM   245  C CB  A SER A 1 28  ? 0.64362   37.44166 -44.41795 0.480 48.62878  ? 28  SER A CB  1 
ATOM   246  C CB  B SER A 1 28  ? 0.56605   37.54080 -44.28446 0.520 46.87559  ? 28  SER A CB  1 
ATOM   247  O OG  A SER A 1 28  ? 0.49804   38.26190 -43.27736 0.480 52.01364  ? 28  SER A OG  1 
ATOM   248  O OG  B SER A 1 28  ? 1.84816   36.94478 -44.25380 0.520 48.58214  ? 28  SER A OG  1 
ATOM   249  N N   . PRO A 1 29  ? -0.08584  34.08736 -44.41184 1.000 47.74715  ? 29  PRO A N   1 
ATOM   250  C CA  . PRO A 1 29  ? 0.08532   32.83861 -43.66302 1.000 50.74334  ? 29  PRO A CA  1 
ATOM   251  C C   . PRO A 1 29  ? 1.30331   32.88000 -42.75642 1.000 54.39158  ? 29  PRO A C   1 
ATOM   252  O O   . PRO A 1 29  ? 2.34541   33.43129 -43.10557 1.000 56.12493  ? 29  PRO A O   1 
ATOM   253  C CB  . PRO A 1 29  ? 0.22466   31.77799 -44.76382 1.000 54.42085  ? 29  PRO A CB  1 
ATOM   254  C CG  . PRO A 1 29  ? 0.56655   32.50532 -45.98856 1.000 56.73581  ? 29  PRO A CG  1 
ATOM   255  C CD  . PRO A 1 29  ? 0.01072   33.89083 -45.86568 1.000 53.75310  ? 29  PRO A CD  1 
ATOM   256  N N   . VAL A 1 30  ? 1.15891   32.29525 -41.56987 1.000 54.02179  ? 30  VAL A N   1 
ATOM   257  C CA  . VAL A 1 30  ? 2.28271   32.19404 -40.64415 1.000 58.79781  ? 30  VAL A CA  1 
ATOM   258  C C   . VAL A 1 30  ? 2.53792   30.78114 -40.16370 1.000 62.87107  ? 30  VAL A C   1 
ATOM   259  O O   . VAL A 1 30  ? 3.66818   30.46914 -39.75131 1.000 70.14553  ? 30  VAL A O   1 
ATOM   260  C CB  . VAL A 1 30  ? 2.08231   33.13513 -39.44068 1.000 60.63966  ? 30  VAL A CB  1 
ATOM   261  C CG1 . VAL A 1 30  ? 1.75517   34.53853 -39.92046 1.000 60.46441  ? 30  VAL A CG1 1 
ATOM   262  C CG2 . VAL A 1 30  ? 0.97491   32.60525 -38.55462 1.000 62.24089  ? 30  VAL A CG2 1 
ATOM   263  N N   . GLY A 1 31  ? 1.56212   29.88934 -40.19984 1.000 61.50045  ? 31  GLY A N   1 
ATOM   264  C CA  . GLY A 1 31  ? 1.78936   28.53808 -39.73414 1.000 66.07622  ? 31  GLY A CA  1 
ATOM   265  C C   . GLY A 1 31  ? 0.69029   27.62973 -40.22158 1.000 67.11533  ? 31  GLY A C   1 
ATOM   266  O O   . GLY A 1 31  ? -0.41159  28.07334 -40.56020 1.000 63.02395  ? 31  GLY A O   1 
ATOM   267  N N   . SER A 1 32  ? 1.00695   26.34274 -40.25937 1.000 69.51290  ? 32  SER A N   1 
ATOM   268  C CA  . SER A 1 32  ? 0.05475   25.35400 -40.72901 1.000 79.10489  ? 32  SER A CA  1 
ATOM   269  C C   . SER A 1 32  ? 0.42772   24.01316 -40.12131 1.000 83.58716  ? 32  SER A C   1 
ATOM   270  O O   . SER A 1 32  ? 1.61116   23.71504 -39.93906 1.000 85.82867  ? 32  SER A O   1 
ATOM   271  C CB  . SER A 1 32  ? 0.03570   25.28465 -42.26252 1.000 85.94668  ? 32  SER A CB  1 
ATOM   272  O OG  . SER A 1 32  ? 0.80698   24.19781 -42.74644 1.000 90.67586  ? 32  SER A OG  1 
ATOM   273  N N   . GLY A 1 33  ? -0.58459  23.23126 -39.79187 1.000 85.62577  ? 33  GLY A N   1 
ATOM   274  C CA  . GLY A 1 33  ? -0.38058  21.91598 -39.23746 1.000 87.87404  ? 33  GLY A CA  1 
ATOM   275  C C   . GLY A 1 33  ? -1.58689  21.04177 -39.47766 1.000 90.44613  ? 33  GLY A C   1 
ATOM   276  O O   . GLY A 1 33  ? -2.44823  21.35104 -40.30325 1.000 93.24357  ? 33  GLY A O   1 
ATOM   277  N N   . ALA A 1 34  ? -1.64220  19.93179 -38.74303 1.000 89.71800  ? 34  ALA A N   1 
ATOM   278  C CA  . ALA A 1 34  ? -2.78194  19.03019 -38.83961 1.000 89.11599  ? 34  ALA A CA  1 
ATOM   279  C C   . ALA A 1 34  ? -4.00100  19.53638 -38.08043 1.000 88.27230  ? 34  ALA A C   1 
ATOM   280  O O   . ALA A 1 34  ? -5.10354  19.02426 -38.30355 1.000 86.19357  ? 34  ALA A O   1 
ATOM   281  C CB  . ALA A 1 34  ? -2.39659  17.63974 -38.33298 1.000 89.56154  ? 34  ALA A CB  1 
ATOM   282  N N   . TYR A 1 35  ? -3.82618  20.52374 -37.19648 1.000 88.94353  ? 35  TYR A N   1 
ATOM   283  C CA  . TYR A 1 35  ? -4.94176  21.11689 -36.46538 1.000 87.27448  ? 35  TYR A CA  1 
ATOM   284  C C   . TYR A 1 35  ? -5.66404  22.17755 -37.28733 1.000 77.07759  ? 35  TYR A C   1 
ATOM   285  O O   . TYR A 1 35  ? -6.88402  22.33950 -37.15403 1.000 68.14811  ? 35  TYR A O   1 
ATOM   286  C CB  . TYR A 1 35  ? -4.43674  21.73879 -35.16047 1.000 92.97839  ? 35  TYR A CB  1 
ATOM   287  C CG  . TYR A 1 35  ? -3.42068  22.84100 -35.38429 1.000 95.71265  ? 35  TYR A CG  1 
ATOM   288  C CD1 . TYR A 1 35  ? -2.09437  22.54294 -35.67182 1.000 96.43455  ? 35  TYR A CD1 1 
ATOM   289  C CD2 . TYR A 1 35  ? -3.79202  24.18012 -35.32508 1.000 97.56421  ? 35  TYR A CD2 1 
ATOM   290  C CE1 . TYR A 1 35  ? -1.16461  23.54660 -35.88679 1.000 97.64789  ? 35  TYR A CE1 1 
ATOM   291  C CE2 . TYR A 1 35  ? -2.86806  25.19149 -35.53785 1.000 98.65922  ? 35  TYR A CE2 1 
ATOM   292  C CZ  . TYR A 1 35  ? -1.55646  24.86832 -35.81822 1.000 99.50477  ? 35  TYR A CZ  1 
ATOM   293  O OH  . TYR A 1 35  ? -0.63330  25.86745 -36.03219 1.000 102.42711 ? 35  TYR A OH  1 
ATOM   294  N N   . GLY A 1 36  ? -4.93617  22.90142 -38.12245 1.000 73.63869  ? 36  GLY A N   1 
ATOM   295  C CA  . GLY A 1 36  ? -5.49989  23.98272 -38.90260 1.000 72.88009  ? 36  GLY A CA  1 
ATOM   296  C C   . GLY A 1 36  ? -4.43749  24.97567 -39.30619 1.000 69.56202  ? 36  GLY A C   1 
ATOM   297  O O   . GLY A 1 36  ? -3.34035  25.02699 -38.74678 1.000 74.79287  ? 36  GLY A O   1 
ATOM   298  N N   . SER A 1 37  ? -4.77665  25.78040 -40.30415 1.000 57.99373  ? 37  SER A N   1 
ATOM   299  C CA  . SER A 1 37  ? -3.87550  26.78980 -40.83390 1.000 54.34905  ? 37  SER A CA  1 
ATOM   300  C C   . SER A 1 37  ? -4.10361  28.11558 -40.11519 1.000 46.54542  ? 37  SER A C   1 
ATOM   301  O O   . SER A 1 37  ? -5.22019  28.42454 -39.68391 1.000 41.08920  ? 37  SER A O   1 
ATOM   302  C CB  . SER A 1 37  ? -4.09743  26.96116 -42.33875 1.000 58.82359  ? 37  SER A CB  1 
ATOM   303  O OG  . SER A 1 37  ? -3.57806  25.85402 -43.05425 1.000 68.70032  ? 37  SER A OG  1 
ATOM   304  N N   . VAL A 1 38  ? -3.03458  28.90040 -39.98132 1.000 43.81986  ? 38  VAL A N   1 
ATOM   305  C CA  . VAL A 1 38  ? -3.11031  30.18588 -39.29336 1.000 39.96672  ? 38  VAL A CA  1 
ATOM   306  C C   . VAL A 1 38  ? -2.59512  31.29392 -40.19963 1.000 41.77963  ? 38  VAL A C   1 
ATOM   307  O O   . VAL A 1 38  ? -1.57888  31.13214 -40.88611 1.000 43.83042  ? 38  VAL A O   1 
ATOM   308  C CB  . VAL A 1 38  ? -2.32376  30.17924 -37.96912 1.000 42.05104  ? 38  VAL A CB  1 
ATOM   309  C CG1 . VAL A 1 38  ? -2.45136  31.53087 -37.29164 1.000 46.09453  ? 38  VAL A CG1 1 
ATOM   310  C CG2 . VAL A 1 38  ? -2.83795  29.09154 -37.05616 1.000 43.26009  ? 38  VAL A CG2 1 
ATOM   311  N N   . CYS A 1 39  ? -3.29431  32.43193 -40.17648 1.000 41.28538  ? 39  CYS A N   1 
ATOM   312  C CA  . CYS A 1 39  ? -2.91090  33.64071 -40.89069 1.000 39.59949  ? 39  CYS A CA  1 
ATOM   313  C C   . CYS A 1 39  ? -2.85436  34.80991 -39.92560 1.000 40.50827  ? 39  CYS A C   1 
ATOM   314  O O   . CYS A 1 39  ? -3.69822  34.92644 -39.03087 1.000 40.01656  ? 39  CYS A O   1 
ATOM   315  C CB  . CYS A 1 39  ? -3.90849  34.00100 -41.98437 1.000 45.07159  ? 39  CYS A CB  1 
ATOM   316  S SG  . CYS A 1 39  ? -3.74794  33.11798 -43.50900 1.000 50.63881  ? 39  CYS A SG  1 
ATOM   317  N N   . ALA A 1 40  ? -1.88312  35.69029 -40.13871 1.000 39.25217  ? 40  ALA A N   1 
ATOM   318  C CA  . ALA A 1 40  ? -1.89969  36.99662 -39.50442 1.000 38.09038  ? 40  ALA A CA  1 
ATOM   319  C C   . ALA A 1 40  ? -2.79414  37.93084 -40.30151 1.000 36.17620  ? 40  ALA A C   1 
ATOM   320  O O   . ALA A 1 40  ? -2.91531  37.80686 -41.52034 1.000 39.84497  ? 40  ALA A O   1 
ATOM   321  C CB  . ALA A 1 40  ? -0.48994  37.57800 -39.41330 1.000 38.38549  ? 40  ALA A CB  1 
ATOM   322  N N   . ALA A 1 41  ? -3.42985  38.86775 -39.60110 1.000 35.04121  ? 41  ALA A N   1 
ATOM   323  C CA  . ALA A 1 41  ? -4.31637  39.82103 -40.25499 1.000 32.48524  ? 41  ALA A CA  1 
ATOM   324  C C   . ALA A 1 41  ? -4.40671  41.07787 -39.41264 1.000 35.82679  ? 41  ALA A C   1 
ATOM   325  O O   . ALA A 1 41  ? -3.99403  41.10972 -38.24969 1.000 36.71660  ? 41  ALA A O   1 
ATOM   326  C CB  . ALA A 1 41  ? -5.71377  39.24958 -40.46989 1.000 32.14185  ? 41  ALA A CB  1 
ATOM   327  N N   . PHE A 1 42  ? -4.96748  42.11594 -40.01457 1.000 33.88421  ? 42  PHE A N   1 
ATOM   328  C CA  . PHE A 1 42  ? -5.24436  43.34659 -39.30501 1.000 34.93811  ? 42  PHE A CA  1 
ATOM   329  C C   . PHE A 1 42  ? -6.75414  43.49507 -39.21452 1.000 34.02353  ? 42  PHE A C   1 
ATOM   330  O O   . PHE A 1 42  ? -7.44514  43.49073 -40.24018 1.000 36.38120  ? 42  PHE A O   1 
ATOM   331  C CB  . PHE A 1 42  ? -4.59893  44.53954 -40.00519 1.000 39.25652  ? 42  PHE A CB  1 
ATOM   332  C CG  . PHE A 1 42  ? -4.87622  45.84402 -39.33553 1.000 43.82860  ? 42  PHE A CG  1 
ATOM   333  C CD1 . PHE A 1 42  ? -4.12744  46.22741 -38.23498 1.000 47.96719  ? 42  PHE A CD1 1 
ATOM   334  C CD2 . PHE A 1 42  ? -5.84171  46.71034 -39.82138 1.000 44.68910  ? 42  PHE A CD2 1 
ATOM   335  C CE1 . PHE A 1 42  ? -4.35735  47.43120 -37.60828 1.000 48.12820  ? 42  PHE A CE1 1 
ATOM   336  C CE2 . PHE A 1 42  ? -6.06810  47.92159 -39.20356 1.000 46.86734  ? 42  PHE A CE2 1 
ATOM   337  C CZ  . PHE A 1 42  ? -5.31930  48.27895 -38.08923 1.000 45.66131  ? 42  PHE A CZ  1 
ATOM   338  N N   . ASP A 1 43  ? -7.26375  43.59415 -37.99020 1.000 31.58517  ? 43  ASP A N   1 
ATOM   339  C CA  . ASP A 1 43  ? -8.69785  43.75723 -37.75145 1.000 28.89385  ? 43  ASP A CA  1 
ATOM   340  C C   . ASP A 1 43  ? -8.99771  45.24466 -37.81675 1.000 31.65266  ? 43  ASP A C   1 
ATOM   341  O O   . ASP A 1 43  ? -8.72993  45.98579 -36.86623 1.000 31.66025  ? 43  ASP A O   1 
ATOM   342  C CB  . ASP A 1 43  ? -9.09309  43.16830 -36.40284 1.000 30.85316  ? 43  ASP A CB  1 
ATOM   343  C CG  . ASP A 1 43  ? -10.57401 43.33499 -36.11475 1.000 32.79586  ? 43  ASP A CG  1 
ATOM   344  O OD1 . ASP A 1 43  ? -11.30491 43.76280 -37.03404 1.000 34.41274  ? 43  ASP A OD1 1 
ATOM   345  O OD2 . ASP A 1 43  ? -11.00624 43.02804 -34.97641 1.000 35.35290  ? 43  ASP A OD2 1 
ATOM   346  N N   . THR A 1 44  ? -9.56065  45.69329 -38.93756 1.000 32.34052  ? 44  THR A N   1 
ATOM   347  C CA  . THR A 1 44  ? -9.78443  47.12162 -39.09042 1.000 36.45211  ? 44  THR A CA  1 
ATOM   348  C C   . THR A 1 44  ? -10.85655 47.63550 -38.14737 1.000 35.59999  ? 44  THR A C   1 
ATOM   349  O O   . THR A 1 44  ? -10.94877 48.85248 -37.93319 1.000 36.26643  ? 44  THR A O   1 
ATOM   350  C CB  . THR A 1 44  ? -10.15544 47.44904 -40.53841 1.000 38.18996  ? 44  THR A CB  1 
ATOM   351  O OG1 . THR A 1 44  ? -11.32958 46.71933 -40.90060 1.000 36.35437  ? 44  THR A OG1 1 
ATOM   352  C CG2 . THR A 1 44  ? -9.01539  47.08409 -41.48582 1.000 41.21688  ? 44  THR A CG2 1 
ATOM   353  N N   . LYS A 1 45  ? -11.65538 46.75073 -37.55707 1.000 36.01492  ? 45  LYS A N   1 
ATOM   354  C CA  . LYS A 1 45  ? -12.71297 47.25780 -36.69442 1.000 40.91992  ? 45  LYS A CA  1 
ATOM   355  C C   . LYS A 1 45  ? -12.20020 47.56884 -35.29194 1.000 33.80719  ? 45  LYS A C   1 
ATOM   356  O O   . LYS A 1 45  ? -12.77056 48.43201 -34.61269 1.000 35.76046  ? 45  LYS A O   1 
ATOM   357  C CB  . LYS A 1 45  ? -13.88727 46.28091 -36.63478 1.000 45.22880  ? 45  LYS A CB  1 
ATOM   358  C CG  . LYS A 1 45  ? -14.72179 46.42078 -35.37104 1.000 57.84163  ? 45  LYS A CG  1 
ATOM   359  C CD  . LYS A 1 45  ? -15.85587 45.40752 -35.30912 1.000 67.34714  ? 45  LYS A CD  1 
ATOM   360  C CE  . LYS A 1 45  ? -16.82529 45.61094 -36.47398 1.000 74.08332  ? 45  LYS A CE  1 
ATOM   361  N NZ  . LYS A 1 45  ? -18.23999 45.75403 -36.00922 1.000 76.67512  ? 45  LYS A NZ  1 
ATOM   362  N N   . THR A 1 46  ? -11.11106 46.92135 -34.86362 1.000 32.57129  ? 46  THR A N   1 
ATOM   363  C CA  . THR A 1 46  ? -10.55180 47.11852 -33.52839 1.000 35.72627  ? 46  THR A CA  1 
ATOM   364  C C   . THR A 1 46  ? -9.15809  47.73218 -33.52082 1.000 35.62714  ? 46  THR A C   1 
ATOM   365  O O   . THR A 1 46  ? -8.69948  48.16517 -32.45324 1.000 37.00235  ? 46  THR A O   1 
ATOM   366  C CB  . THR A 1 46  ? -10.46999 45.78672 -32.76281 1.000 36.25785  ? 46  THR A CB  1 
ATOM   367  O OG1 . THR A 1 46  ? -9.62351  44.87411 -33.47671 1.000 34.11741  ? 46  THR A OG1 1 
ATOM   368  C CG2 . THR A 1 46  ? -11.85598 45.16291 -32.56722 1.000 37.25528  ? 46  THR A CG2 1 
ATOM   369  N N   . GLY A 1 47  ? -8.46280  47.75105 -34.65685 1.000 36.57941  ? 47  GLY A N   1 
ATOM   370  C CA  . GLY A 1 47  ? -7.08841  48.19620 -34.70474 1.000 36.66922  ? 47  GLY A CA  1 
ATOM   371  C C   . GLY A 1 47  ? -6.07801  47.18294 -34.22327 1.000 35.58287  ? 47  GLY A C   1 
ATOM   372  O O   . GLY A 1 47  ? -4.92658  47.55489 -33.97896 1.000 41.28696  ? 47  GLY A O   1 
ATOM   373  N N   . LEU A 1 48  ? -6.46410  45.91598 -34.06844 1.000 32.72094  ? 48  LEU A N   1 
ATOM   374  C CA  . LEU A 1 48  ? -5.57174  44.90398 -33.51975 1.000 34.33696  ? 48  LEU A CA  1 
ATOM   375  C C   . LEU A 1 48  ? -4.97689  44.03782 -34.61835 1.000 37.85722  ? 48  LEU A C   1 
ATOM   376  O O   . LEU A 1 48  ? -5.64696  43.72059 -35.60910 1.000 38.00713  ? 48  LEU A O   1 
ATOM   377  C CB  . LEU A 1 48  ? -6.29804  44.01344 -32.50353 1.000 36.87087  ? 48  LEU A CB  1 
ATOM   378  C CG  . LEU A 1 48  ? -7.01066  44.71265 -31.33262 1.000 39.92235  ? 48  LEU A CG  1 
ATOM   379  C CD1 . LEU A 1 48  ? -7.99274  43.75303 -30.64966 1.000 40.12094  ? 48  LEU A CD1 1 
ATOM   380  C CD2 . LEU A 1 48  ? -6.01690  45.28640 -30.31402 1.000 38.07912  ? 48  LEU A CD2 1 
ATOM   381  N N   . ARG A 1 49  ? -3.70379  43.67268 -34.44253 1.000 39.83166  ? 49  ARG A N   1 
ATOM   382  C CA  . ARG A 1 49  ? -3.13315  42.58498 -35.21789 1.000 41.16649  ? 49  ARG A CA  1 
ATOM   383  C C   . ARG A 1 49  ? -3.60115  41.27533 -34.60083 1.000 39.12071  ? 49  ARG A C   1 
ATOM   384  O O   . ARG A 1 49  ? -3.52481  41.08510 -33.37965 1.000 39.68936  ? 49  ARG A O   1 
ATOM   385  C CB  . ARG A 1 49  ? -1.60912  42.66438 -35.26687 1.000 47.08910  ? 49  ARG A CB  1 
ATOM   386  C CG  . ARG A 1 49  ? -1.08875  43.99168 -35.78186 1.000 62.82059  ? 49  ARG A CG  1 
ATOM   387  C CD  . ARG A 1 49  ? 0.02589   43.78588 -36.79978 1.000 79.09142  ? 49  ARG A CD  1 
ATOM   388  N NE  . ARG A 1 49  ? 0.97301   44.89547 -36.82842 1.000 90.82879  ? 49  ARG A NE  1 
ATOM   389  C CZ  . ARG A 1 49  ? 0.95524   45.87607 -37.72282 1.000 96.09140  ? 49  ARG A CZ  1 
ATOM   390  N NH1 . ARG A 1 49  ? 0.00533   45.95761 -38.64259 1.000 93.24914  ? 49  ARG A NH1 1 
ATOM   391  N NH2 . ARG A 1 49  ? 1.91158   46.80098 -37.69053 1.000 99.53711  ? 49  ARG A NH2 1 
ATOM   392  N N   . VAL A 1 50  ? -4.13371  40.39039 -35.44056 1.000 35.71633  ? 50  VAL A N   1 
ATOM   393  C CA  . VAL A 1 50  ? -4.82974  39.21137 -34.95507 1.000 33.33907  ? 50  VAL A CA  1 
ATOM   394  C C   . VAL A 1 50  ? -4.27989  37.98433 -35.66539 1.000 35.11827  ? 50  VAL A C   1 
ATOM   395  O O   . VAL A 1 50  ? -3.75179  38.05949 -36.77880 1.000 37.14974  ? 50  VAL A O   1 
ATOM   396  C CB  . VAL A 1 50  ? -6.35007  39.30530 -35.18867 1.000 31.29294  ? 50  VAL A CB  1 
ATOM   397  C CG1 . VAL A 1 50  ? -6.94830  40.42071 -34.34893 1.000 30.73450  ? 50  VAL A CG1 1 
ATOM   398  C CG2 . VAL A 1 50  ? -6.63488  39.52140 -36.67020 1.000 35.09265  ? 50  VAL A CG2 1 
ATOM   399  N N   . ALA A 1 51  ? -4.42966  36.84548 -35.00005 1.000 32.92603  ? 51  ALA A N   1 
ATOM   400  C CA  . ALA A 1 51  ? -4.23435  35.53139 -35.59720 1.000 33.15377  ? 51  ALA A CA  1 
ATOM   401  C C   . ALA A 1 51  ? -5.60279  34.94853 -35.93590 1.000 33.15213  ? 51  ALA A C   1 
ATOM   402  O O   . ALA A 1 51  ? -6.48995  34.89270 -35.07247 1.000 33.93339  ? 51  ALA A O   1 
ATOM   403  C CB  . ALA A 1 51  ? -3.48658  34.60437 -34.63539 1.000 32.88425  ? 51  ALA A CB  1 
ATOM   404  N N   . VAL A 1 52  ? -5.77563  34.52280 -37.18732 1.000 33.20322  ? 52  VAL A N   1 
ATOM   405  C CA  . VAL A 1 52  ? -7.00071  33.87489 -37.64637 1.000 31.41832  ? 52  VAL A CA  1 
ATOM   406  C C   . VAL A 1 52  ? -6.66379  32.42247 -37.93732 1.000 33.24826  ? 52  VAL A C   1 
ATOM   407  O O   . VAL A 1 52  ? -5.83330  32.13427 -38.80710 1.000 35.06434  ? 52  VAL A O   1 
ATOM   408  C CB  . VAL A 1 52  ? -7.58661  34.55420 -38.89586 1.000 31.38867  ? 52  VAL A CB  1 
ATOM   409  C CG1 . VAL A 1 52  ? -8.94218  33.92582 -39.25329 1.000 34.30865  ? 52  VAL A CG1 1 
ATOM   410  C CG2 . VAL A 1 52  ? -7.70502  36.06702 -38.69683 1.000 35.07195  ? 52  VAL A CG2 1 
ATOM   411  N N   . LYS A 1 53  ? -7.30466  31.50884 -37.21986 1.000 31.47319  ? 53  LYS A N   1 
ATOM   412  C CA  . LYS A 1 53  ? -7.03166  30.08531 -37.35920 1.000 31.51569  ? 53  LYS A CA  1 
ATOM   413  C C   . LYS A 1 53  ? -8.24977  29.42667 -37.99812 1.000 34.23947  ? 53  LYS A C   1 
ATOM   414  O O   . LYS A 1 53  ? -9.35915  29.50590 -37.46038 1.000 34.70078  ? 53  LYS A O   1 
ATOM   415  C CB  . LYS A 1 53  ? -6.73113  29.44043 -36.01150 1.000 31.92079  ? 53  LYS A CB  1 
ATOM   416  C CG  . LYS A 1 53  ? -6.49623  27.93409 -36.15472 1.000 36.33258  ? 53  LYS A CG  1 
ATOM   417  C CD  . LYS A 1 53  ? -5.81819  27.26401 -34.95200 1.000 41.23662  ? 53  LYS A CD  1 
ATOM   418  C CE  . LYS A 1 53  ? -6.70104  27.30988 -33.71762 1.000 44.76004  ? 53  LYS A CE  1 
ATOM   419  N NZ  . LYS A 1 53  ? -6.11212  26.53167 -32.58439 1.000 49.60295  ? 53  LYS A NZ  1 
ATOM   420  N N   . LYS A 1 54  ? -8.04647  28.78566 -39.13899 1.000 32.08483  ? 54  LYS A N   1 
ATOM   421  C CA  . LYS A 1 54  ? -9.09228  28.01909 -39.79594 1.000 32.90520  ? 54  LYS A CA  1 
ATOM   422  C C   . LYS A 1 54  ? -8.91982  26.56109 -39.40618 1.000 34.26736  ? 54  LYS A C   1 
ATOM   423  O O   . LYS A 1 54  ? -7.89450  25.95497 -39.72630 1.000 36.84704  ? 54  LYS A O   1 
ATOM   424  C CB  . LYS A 1 54  ? -9.02013  28.18016 -41.31716 1.000 34.25252  ? 54  LYS A CB  1 
ATOM   425  C CG  . LYS A 1 54  ? -10.07323 27.35841 -42.06786 1.000 37.35243  ? 54  LYS A CG  1 
ATOM   426  C CD  . LYS A 1 54  ? -9.89151  27.46693 -43.58408 1.000 36.83030  ? 54  LYS A CD  1 
ATOM   427  C CE  . LYS A 1 54  ? -11.08835 26.89576 -44.33561 1.000 39.16299  ? 54  LYS A CE  1 
ATOM   428  N NZ  . LYS A 1 54  ? -10.76163 26.53429 -45.72599 1.000 40.58104  ? 54  LYS A NZ  1 
ATOM   429  N N   . LEU A 1 55  ? -9.90035  26.00724 -38.70029 1.000 32.62918  ? 55  LEU A N   1 
ATOM   430  C CA  . LEU A 1 55  ? -9.77176  24.62374 -38.26152 1.000 33.08264  ? 55  LEU A CA  1 
ATOM   431  C C   . LEU A 1 55  ? -9.76963  23.69234 -39.46435 1.000 39.20221  ? 55  LEU A C   1 
ATOM   432  O O   . LEU A 1 55  ? -10.48111 23.91493 -40.44819 1.000 41.35322  ? 55  LEU A O   1 
ATOM   433  C CB  . LEU A 1 55  ? -10.90066 24.25645 -37.30945 1.000 34.60004  ? 55  LEU A CB  1 
ATOM   434  C CG  . LEU A 1 55  ? -10.86977 25.00104 -35.96798 1.000 38.80576  ? 55  LEU A CG  1 
ATOM   435  C CD1 . LEU A 1 55  ? -11.96084 24.46839 -35.03660 1.000 39.65797  ? 55  LEU A CD1 1 
ATOM   436  C CD2 . LEU A 1 55  ? -9.50478  24.89856 -35.30286 1.000 42.66286  ? 55  LEU A CD2 1 
ATOM   437  N N   . SER A 1 56  ? -8.94754  22.65430 -39.38678 1.000 41.51789  ? 56  SER A N   1 
ATOM   438  C CA  . SER A 1 56  ? -8.83499  21.65990 -40.43854 1.000 49.31052  ? 56  SER A CA  1 
ATOM   439  C C   . SER A 1 56  ? -9.73379  20.47819 -40.09029 1.000 56.28050  ? 56  SER A C   1 
ATOM   440  O O   . SER A 1 56  ? -9.55695  19.84916 -39.04407 1.000 59.09644  ? 56  SER A O   1 
ATOM   441  C CB  . SER A 1 56  ? -7.38330  21.21172 -40.59815 1.000 54.42545  ? 56  SER A CB  1 
ATOM   442  O OG  . SER A 1 56  ? -7.31140  20.10144 -41.46470 1.000 59.90386  ? 56  SER A OG  1 
ATOM   443  N N   . ARG A 1 57  ? -10.70079 20.19227 -40.95339 1.000 59.22875  ? 57  ARG A N   1 
ATOM   444  C CA  . ARG A 1 57  ? -11.59996 19.05847 -40.78240 1.000 61.94083  ? 57  ARG A CA  1 
ATOM   445  C C   . ARG A 1 57  ? -12.20214 19.06104 -39.37203 1.000 55.06526  ? 57  ARG A C   1 
ATOM   446  O O   . ARG A 1 57  ? -12.04951 18.09641 -38.62391 1.000 55.76053  ? 57  ARG A O   1 
ATOM   447  C CB  . ARG A 1 57  ? -10.87768 17.74664 -41.05763 1.000 74.46125  ? 57  ARG A CB  1 
ATOM   448  C CG  . ARG A 1 57  ? -10.82249 17.34663 -42.53708 1.000 85.28517  ? 57  ARG A CG  1 
ATOM   449  C CD  . ARG A 1 57  ? -12.06552 17.79260 -43.31254 1.000 91.76357  ? 57  ARG A CD  1 
ATOM   450  N NE  . ARG A 1 57  ? -13.29434 17.18255 -42.81233 1.000 94.43645  ? 57  ARG A NE  1 
ATOM   451  C CZ  . ARG A 1 57  ? -14.35973 16.91801 -43.55825 1.000 94.02838  ? 57  ARG A CZ  1 
ATOM   452  N NH1 . ARG A 1 57  ? -14.39657 17.22446 -44.84594 1.000 94.60295  ? 57  ARG A NH1 1 
ATOM   453  N NH2 . ARG A 1 57  ? -15.41822 16.33960 -42.99607 1.000 91.43424  ? 57  ARG A NH2 1 
ATOM   454  N N   . PRO A 1 58  ? -12.89479 20.13686 -38.99332 1.000 46.80786  ? 58  PRO A N   1 
ATOM   455  C CA  . PRO A 1 58  ? -13.40293 20.23021 -37.61155 1.000 42.00613  ? 58  PRO A CA  1 
ATOM   456  C C   . PRO A 1 58  ? -14.31958 19.09398 -37.19843 1.000 41.88288  ? 58  PRO A C   1 
ATOM   457  O O   . PRO A 1 58  ? -14.36870 18.76058 -36.00467 1.000 40.17802  ? 58  PRO A O   1 
ATOM   458  C CB  . PRO A 1 58  ? -14.14760 21.57390 -37.60074 1.000 40.98375  ? 58  PRO A CB  1 
ATOM   459  C CG  . PRO A 1 58  ? -14.49040 21.84309 -39.05330 1.000 45.62707  ? 58  PRO A CG  1 
ATOM   460  C CD  . PRO A 1 58  ? -13.39444 21.21535 -39.86152 1.000 47.96552  ? 58  PRO A CD  1 
ATOM   461  N N   . PHE A 1 59  ? -15.04858 18.48829 -38.13714 1.000 41.66277  ? 59  PHE A N   1 
ATOM   462  C CA  . PHE A 1 59  ? -16.11254 17.54666 -37.81244 1.000 39.89204  ? 59  PHE A CA  1 
ATOM   463  C C   . PHE A 1 59  ? -15.93917 16.21358 -38.53273 1.000 45.11646  ? 59  PHE A C   1 
ATOM   464  O O   . PHE A 1 59  ? -16.92185 15.52050 -38.81263 1.000 44.58445  ? 59  PHE A O   1 
ATOM   465  C CB  . PHE A 1 59  ? -17.46631 18.16051 -38.14864 1.000 39.08921  ? 59  PHE A CB  1 
ATOM   466  C CG  . PHE A 1 59  ? -17.68315 19.51112 -37.51852 1.000 40.72488  ? 59  PHE A CG  1 
ATOM   467  C CD1 . PHE A 1 59  ? -17.73094 19.64402 -36.13898 1.000 39.48470  ? 59  PHE A CD1 1 
ATOM   468  C CD2 . PHE A 1 59  ? -17.78020 20.65227 -38.29824 1.000 41.97195  ? 59  PHE A CD2 1 
ATOM   469  C CE1 . PHE A 1 59  ? -17.91703 20.89164 -35.55222 1.000 39.16860  ? 59  PHE A CE1 1 
ATOM   470  C CE2 . PHE A 1 59  ? -17.94780 21.89507 -37.72348 1.000 38.84051  ? 59  PHE A CE2 1 
ATOM   471  C CZ  . PHE A 1 59  ? -18.02299 22.01826 -36.34617 1.000 38.69585  ? 59  PHE A CZ  1 
ATOM   472  N N   A GLN A 1 60  ? -14.69874 15.81925 -38.80992 0.650 45.39572  ? 60  GLN A N   1 
ATOM   473  N N   B GLN A 1 60  ? -14.69638 15.83071 -38.82310 0.350 45.54052  ? 60  GLN A N   1 
ATOM   474  C CA  A GLN A 1 60  ? -14.48339 14.62855 -39.62238 0.650 45.43062  ? 60  GLN A CA  1 
ATOM   475  C CA  B GLN A 1 60  ? -14.45651 14.62681 -39.61113 0.350 45.93993  ? 60  GLN A CA  1 
ATOM   476  C C   A GLN A 1 60  ? -14.65542 13.32484 -38.84348 0.650 47.10458  ? 60  GLN A C   1 
ATOM   477  C C   B GLN A 1 60  ? -14.75072 13.34040 -38.84408 0.350 47.13735  ? 60  GLN A C   1 
ATOM   478  O O   A GLN A 1 60  ? -14.73748 12.26044 -39.46544 0.650 45.93383  ? 60  GLN A O   1 
ATOM   479  O O   B GLN A 1 60  ? -15.00517 12.30725 -39.47187 0.350 46.59175  ? 60  GLN A O   1 
ATOM   480  C CB  A GLN A 1 60  ? -13.09666 14.68935 -40.26495 0.650 52.54953  ? 60  GLN A CB  1 
ATOM   481  C CB  B GLN A 1 60  ? -13.01598 14.63187 -40.11464 0.350 49.26495  ? 60  GLN A CB  1 
ATOM   482  C CG  A GLN A 1 60  ? -12.13353 13.62084 -39.81135 0.650 60.65472  ? 60  GLN A CG  1 
ATOM   483  C CG  B GLN A 1 60  ? -11.99051 14.68401 -39.00672 0.350 52.69089  ? 60  GLN A CG  1 
ATOM   484  C CD  A GLN A 1 60  ? -10.88490 13.57145 -40.67595 0.650 67.36939  ? 60  GLN A CD  1 
ATOM   485  C CD  B GLN A 1 60  ? -10.60688 14.28425 -39.47492 0.350 58.67627  ? 60  GLN A CD  1 
ATOM   486  O OE1 A GLN A 1 60  ? -9.77889  13.83098 -40.20139 0.650 68.87886  ? 60  GLN A OE1 1 
ATOM   487  O OE1 B GLN A 1 60  ? -9.61396  14.91523 -39.11263 0.350 56.98050  ? 60  GLN A OE1 1 
ATOM   488  N NE2 A GLN A 1 60  ? -11.06086 13.26566 -41.95798 0.650 68.09129  ? 60  GLN A NE2 1 
ATOM   489  N NE2 B GLN A 1 60  ? -10.53257 13.23030 -40.28187 0.350 61.89853  ? 60  GLN A NE2 1 
ATOM   490  N N   . SER A 1 61  ? -14.72847 13.37430 -37.51484 1.000 46.86850  ? 61  SER A N   1 
ATOM   491  C CA  . SER A 1 61  ? -15.02771 12.19497 -36.70768 1.000 46.81804  ? 61  SER A CA  1 
ATOM   492  C C   . SER A 1 61  ? -15.63162 12.64910 -35.38642 1.000 43.50932  ? 61  SER A C   1 
ATOM   493  O O   . SER A 1 61  ? -15.64475 13.84022 -35.06049 1.000 41.36167  ? 61  SER A O   1 
ATOM   494  C CB  . SER A 1 61  ? -13.78647 11.35232 -36.43357 1.000 48.90559  ? 61  SER A CB  1 
ATOM   495  O OG  . SER A 1 61  ? -12.94564 12.02447 -35.50472 1.000 51.61926  ? 61  SER A OG  1 
ATOM   496  N N   . ILE A 1 62  ? -16.12126 11.68478 -34.60504 1.000 42.40354  ? 62  ILE A N   1 
ATOM   497  C CA  . ILE A 1 62  ? -16.67014 12.05098 -33.30369 1.000 42.81830  ? 62  ILE A CA  1 
ATOM   498  C C   . ILE A 1 62  ? -15.58593 12.68181 -32.44131 1.000 42.09427  ? 62  ILE A C   1 
ATOM   499  O O   . ILE A 1 62  ? -15.79969 13.70813 -31.78516 1.000 42.71465  ? 62  ILE A O   1 
ATOM   500  C CB  . ILE A 1 62  ? -17.28646 10.83111 -32.60589 1.000 46.33432  ? 62  ILE A CB  1 
ATOM   501  C CG1 . ILE A 1 62  ? -18.65578 10.51712 -33.20294 1.000 46.83147  ? 62  ILE A CG1 1 
ATOM   502  C CG2 . ILE A 1 62  ? -17.45256 11.13796 -31.12907 1.000 45.50252  ? 62  ILE A CG2 1 
ATOM   503  C CD1 . ILE A 1 62  ? -19.23481 9.20073  -32.71793 1.000 48.15065  ? 62  ILE A CD1 1 
ATOM   504  N N   . ILE A 1 63  ? -14.40500 12.06945 -32.42507 1.000 38.65745  ? 63  ILE A N   1 
ATOM   505  C CA  . ILE A 1 63  ? -13.30721 12.60951 -31.63350 1.000 44.66249  ? 63  ILE A CA  1 
ATOM   506  C C   . ILE A 1 63  ? -12.96375 14.02493 -32.08927 1.000 46.53351  ? 63  ILE A C   1 
ATOM   507  O O   . ILE A 1 63  ? -12.79669 14.93397 -31.26400 1.000 43.22188  ? 63  ILE A O   1 
ATOM   508  C CB  . ILE A 1 63  ? -12.09754 11.66284 -31.70246 1.000 52.59444  ? 63  ILE A CB  1 
ATOM   509  C CG1 . ILE A 1 63  ? -12.48998 10.29309 -31.14614 1.000 58.07176  ? 63  ILE A CG1 1 
ATOM   510  C CG2 . ILE A 1 63  ? -10.91752 12.23805 -30.94968 1.000 51.49530  ? 63  ILE A CG2 1 
ATOM   511  C CD1 . ILE A 1 63  ? -11.34344 9.52897  -30.53972 1.000 63.69627  ? 63  ILE A CD1 1 
ATOM   512  N N   . HIS A 1 64  ? -12.88354 14.24055 -33.40671 1.000 44.43493  ? 64  HIS A N   1 
ATOM   513  C CA  . HIS A 1 64  ? -12.61812 15.57843 -33.93250 1.000 42.82122  ? 64  HIS A CA  1 
ATOM   514  C C   . HIS A 1 64  ? -13.74102 16.55093 -33.58150 1.000 39.30229  ? 64  HIS A C   1 
ATOM   515  O O   . HIS A 1 64  ? -13.48752 17.70282 -33.21091 1.000 36.50388  ? 64  HIS A O   1 
ATOM   516  C CB  . HIS A 1 64  ? -12.42973 15.52759 -35.44908 1.000 51.18179  ? 64  HIS A CB  1 
ATOM   517  C CG  . HIS A 1 64  ? -11.15703 14.87248 -35.88753 1.000 62.37785  ? 64  HIS A CG  1 
ATOM   518  N ND1 . HIS A 1 64  ? -11.05374 13.51595 -36.11130 1.000 67.83439  ? 64  HIS A ND1 1 
ATOM   519  C CD2 . HIS A 1 64  ? -9.94110  15.39440 -36.17753 1.000 65.05561  ? 64  HIS A CD2 1 
ATOM   520  C CE1 . HIS A 1 64  ? -9.82431  13.22740 -36.50065 1.000 66.50042  ? 64  HIS A CE1 1 
ATOM   521  N NE2 . HIS A 1 64  ? -9.12982  14.35019 -36.55346 1.000 62.33016  ? 64  HIS A NE2 1 
ATOM   522  N N   . ALA A 1 65  ? -14.99325 16.11949 -33.72990 1.000 37.59067  ? 65  ALA A N   1 
ATOM   523  C CA  . ALA A 1 65  ? -16.10563 17.02832 -33.47524 1.000 34.52052  ? 65  ALA A CA  1 
ATOM   524  C C   . ALA A 1 65  ? -16.13383 17.45655 -32.01316 1.000 34.09594  ? 65  ALA A C   1 
ATOM   525  O O   . ALA A 1 65  ? -16.36917 18.63248 -31.70215 1.000 34.55243  ? 65  ALA A O   1 
ATOM   526  C CB  . ALA A 1 65  ? -17.42958 16.37338 -33.87870 1.000 35.82719  ? 65  ALA A CB  1 
ATOM   527  N N   . LYS A 1 66  ? -15.87769 16.51951 -31.09789 1.000 32.89305  ? 66  LYS A N   1 
ATOM   528  C CA  . LYS A 1 66  ? -15.85636 16.86438 -29.67810 1.000 31.22611  ? 66  LYS A CA  1 
ATOM   529  C C   . LYS A 1 66  ? -14.70089 17.80898 -29.35471 1.000 29.40786  ? 66  LYS A C   1 
ATOM   530  O O   . LYS A 1 66  ? -14.85293 18.73846 -28.55224 1.000 33.39790  ? 66  LYS A O   1 
ATOM   531  C CB  . LYS A 1 66  ? -15.77118 15.58998 -28.83308 1.000 35.68933  ? 66  LYS A CB  1 
ATOM   532  C CG  . LYS A 1 66  ? -16.12420 15.80894 -27.36434 1.000 35.30203  ? 66  LYS A CG  1 
ATOM   533  C CD  . LYS A 1 66  ? -16.16730 14.51386 -26.60393 1.000 34.49565  ? 66  LYS A CD  1 
ATOM   534  C CE  . LYS A 1 66  ? -16.22155 14.74013 -25.09155 1.000 36.46672  ? 66  LYS A CE  1 
ATOM   535  N NZ  . LYS A 1 66  ? -16.30780 13.42617 -24.40557 1.000 43.59924  ? 66  LYS A NZ  1 
ATOM   536  N N   . ARG A 1 67  ? -13.53506 17.57654 -29.95570 1.000 31.13329  ? 67  ARG A N   1 
ATOM   537  C CA  . ARG A 1 67  ? -12.37579 18.42472 -29.69750 1.000 32.52236  ? 67  ARG A CA  1 
ATOM   538  C C   . ARG A 1 67  ? -12.63989 19.84789 -30.16723 1.000 31.68606  ? 67  ARG A C   1 
ATOM   539  O O   . ARG A 1 67  ? -12.25839 20.81711 -29.49689 1.000 32.71000  ? 67  ARG A O   1 
ATOM   540  C CB  . ARG A 1 67  ? -11.14643 17.83429 -30.39375 1.000 36.17297  ? 67  ARG A CB  1 
ATOM   541  C CG  . ARG A 1 67  ? -9.79060  18.30948 -29.83922 1.000 43.76927  ? 67  ARG A CG  1 
ATOM   542  C CD  . ARG A 1 67  ? -8.80318  18.67500 -30.93406 1.000 50.75072  ? 67  ARG A CD  1 
ATOM   543  N NE  . ARG A 1 67  ? -9.33657  19.68533 -31.84263 1.000 60.97822  ? 67  ARG A NE  1 
ATOM   544  C CZ  . ARG A 1 67  ? -9.18179  20.99423 -31.67599 1.000 63.23502  ? 67  ARG A CZ  1 
ATOM   545  N NH1 . ARG A 1 67  ? -8.46756  21.48481 -30.67697 1.000 62.51628  ? 67  ARG A NH1 1 
ATOM   546  N NH2 . ARG A 1 67  ? -9.75053  21.83179 -32.53794 1.000 63.25127  ? 67  ARG A NH2 1 
ATOM   547  N N   . THR A 1 68  ? -13.29899 19.99144 -31.31802 1.000 30.21629  ? 68  THR A N   1 
ATOM   548  C CA  . THR A 1 68  ? -13.67076 21.32067 -31.80478 1.000 32.32392  ? 68  THR A CA  1 
ATOM   549  C C   . THR A 1 68  ? -14.58179 22.02567 -30.81007 1.000 31.66086  ? 68  THR A C   1 
ATOM   550  O O   . THR A 1 68  ? -14.39730 23.21192 -30.49954 1.000 30.31281  ? 68  THR A O   1 
ATOM   551  C CB  . THR A 1 68  ? -14.35159 21.19124 -33.17382 1.000 31.53406  ? 68  THR A CB  1 
ATOM   552  O OG1 . THR A 1 68  ? -13.41627 20.61281 -34.09576 1.000 34.48559  ? 68  THR A OG1 1 
ATOM   553  C CG2 . THR A 1 68  ? -14.81852 22.54891 -33.69563 1.000 30.45257  ? 68  THR A CG2 1 
ATOM   554  N N   . TYR A 1 69  ? -15.58915 21.31182 -30.31796 1.000 31.84827  ? 69  TYR A N   1 
ATOM   555  C CA  . TYR A 1 69  ? -16.47952 21.87858 -29.30810 1.000 30.04197  ? 69  TYR A CA  1 
ATOM   556  C C   . TYR A 1 69  ? -15.71506 22.22438 -28.03402 1.000 32.01916  ? 69  TYR A C   1 
ATOM   557  O O   . TYR A 1 69  ? -15.91243 23.30198 -27.44866 1.000 28.35082  ? 69  TYR A O   1 
ATOM   558  C CB  . TYR A 1 69  ? -17.61524 20.89822 -29.01332 1.000 30.49408  ? 69  TYR A CB  1 
ATOM   559  C CG  . TYR A 1 69  ? -18.59748 21.39463 -27.98437 1.000 32.37953  ? 69  TYR A CG  1 
ATOM   560  C CD1 . TYR A 1 69  ? -19.49188 22.42870 -28.26425 1.000 27.39495  ? 69  TYR A CD1 1 
ATOM   561  C CD2 . TYR A 1 69  ? -18.61695 20.83766 -26.71199 1.000 30.41484  ? 69  TYR A CD2 1 
ATOM   562  C CE1 . TYR A 1 69  ? -20.38763 22.87558 -27.29544 1.000 29.38975  ? 69  TYR A CE1 1 
ATOM   563  C CE2 . TYR A 1 69  ? -19.49003 21.27803 -25.74196 1.000 31.79355  ? 69  TYR A CE2 1 
ATOM   564  C CZ  . TYR A 1 69  ? -20.38063 22.28951 -26.03177 1.000 27.36356  ? 69  TYR A CZ  1 
ATOM   565  O OH  . TYR A 1 69  ? -21.25047 22.69631 -25.04102 1.000 32.20002  ? 69  TYR A OH  1 
ATOM   566  N N   . ARG A 1 70  ? -14.81571 21.33631 -27.60848 1.000 30.27464  ? 70  ARG A N   1 
ATOM   567  C CA  . ARG A 1 70  ? -14.04591 21.58047 -26.39341 1.000 27.75617  ? 70  ARG A CA  1 
ATOM   568  C C   . ARG A 1 70  ? -13.19718 22.84293 -26.52446 1.000 27.68403  ? 70  ARG A C   1 
ATOM   569  O O   . ARG A 1 70  ? -13.16316 23.67789 -25.60727 1.000 28.14714  ? 70  ARG A O   1 
ATOM   570  C CB  . ARG A 1 70  ? -13.16567 20.36437 -26.07079 1.000 30.55750  ? 70  ARG A CB  1 
ATOM   571  C CG  . ARG A 1 70  ? -12.14390 20.57782 -24.94239 1.000 32.33720  ? 70  ARG A CG  1 
ATOM   572  C CD  . ARG A 1 70  ? -11.17633 19.39162 -24.83170 1.000 33.90729  ? 70  ARG A CD  1 
ATOM   573  N NE  . ARG A 1 70  ? -11.89381 18.13868 -24.60378 1.000 39.20481  ? 70  ARG A NE  1 
ATOM   574  C CZ  . ARG A 1 70  ? -11.89087 17.09014 -25.42120 1.000 45.43614  ? 70  ARG A CZ  1 
ATOM   575  N NH1 . ARG A 1 70  ? -11.15907 17.07131 -26.52692 1.000 47.91841  ? 70  ARG A NH1 1 
ATOM   576  N NH2 . ARG A 1 70  ? -12.63686 16.02745 -25.11746 1.000 42.04369  ? 70  ARG A NH2 1 
ATOM   577  N N   . GLU A 1 71  ? -12.51320 23.00654 -27.66448 1.000 29.11845  ? 71  GLU A N   1 
ATOM   578  C CA  . GLU A 1 71  ? -11.67472 24.18772 -27.86636 1.000 29.06733  ? 71  GLU A CA  1 
ATOM   579  C C   . GLU A 1 71  ? -12.49552 25.47597 -27.82486 1.000 31.23054  ? 71  GLU A C   1 
ATOM   580  O O   . GLU A 1 71  ? -12.10448 26.46151 -27.18037 1.000 30.11674  ? 71  GLU A O   1 
ATOM   581  C CB  . GLU A 1 71  ? -10.91402 24.09406 -29.19901 1.000 31.11865  ? 71  GLU A CB  1 
ATOM   582  C CG  . GLU A 1 71  ? -9.75737  25.09686 -29.23085 1.000 34.61915  ? 71  GLU A CG  1 
ATOM   583  C CD  . GLU A 1 71  ? -8.98937  25.18829 -30.54050 1.000 43.66408  ? 71  GLU A CD  1 
ATOM   584  O OE1 . GLU A 1 71  ? -9.19673  24.36746 -31.46192 1.000 44.87042  ? 71  GLU A OE1 1 
ATOM   585  O OE2 . GLU A 1 71  ? -8.11578  26.08095 -30.61577 1.000 42.25460  ? 71  GLU A OE2 1 
ATOM   586  N N   . LEU A 1 72  ? -13.62913 25.49338 -28.52862 1.000 29.61284  ? 72  LEU A N   1 
ATOM   587  C CA  . LEU A 1 72  ? -14.46945 26.68581 -28.55315 1.000 28.81752  ? 72  LEU A CA  1 
ATOM   588  C C   . LEU A 1 72  ? -15.01740 27.01217 -27.16137 1.000 28.85201  ? 72  LEU A C   1 
ATOM   589  O O   . LEU A 1 72  ? -15.02207 28.17910 -26.74364 1.000 29.17007  ? 72  LEU A O   1 
ATOM   590  C CB  . LEU A 1 72  ? -15.62301 26.49260 -29.54063 1.000 27.93187  ? 72  LEU A CB  1 
ATOM   591  C CG  . LEU A 1 72  ? -16.51100 27.69498 -29.84192 1.000 29.64759  ? 72  LEU A CG  1 
ATOM   592  C CD1 . LEU A 1 72  ? -15.69015 28.98668 -29.95652 1.000 33.15163  ? 72  LEU A CD1 1 
ATOM   593  C CD2 . LEU A 1 72  ? -17.41616 27.46801 -31.06995 1.000 30.20936  ? 72  LEU A CD2 1 
ATOM   594  N N   . ARG A 1 73  ? -15.49289 25.99581 -26.42955 1.000 26.20086  ? 73  ARG A N   1 
ATOM   595  C CA  . ARG A 1 73  ? -15.97301 26.23355 -25.06436 1.000 27.14814  ? 73  ARG A CA  1 
ATOM   596  C C   . ARG A 1 73  ? -14.87913 26.83517 -24.19708 1.000 28.08934  ? 73  ARG A C   1 
ATOM   597  O O   . ARG A 1 73  ? -15.12537 27.77631 -23.42833 1.000 28.06395  ? 73  ARG A O   1 
ATOM   598  C CB  . ARG A 1 73  ? -16.48038 24.93151 -24.43906 1.000 26.41625  ? 73  ARG A CB  1 
ATOM   599  C CG  . ARG A 1 73  ? -17.85488 24.44903 -24.94262 1.000 27.70734  ? 73  ARG A CG  1 
ATOM   600  C CD  . ARG A 1 73  ? -19.00287 25.37142 -24.47861 1.000 28.35797  ? 73  ARG A CD  1 
ATOM   601  N NE  . ARG A 1 73  ? -18.96442 25.62955 -23.03812 1.000 29.82062  ? 73  ARG A NE  1 
ATOM   602  C CZ  . ARG A 1 73  ? -19.35376 24.76753 -22.10598 1.000 30.88962  ? 73  ARG A CZ  1 
ATOM   603  N NH1 . ARG A 1 73  ? -19.92124 23.61149 -22.42562 1.000 33.72786  ? 73  ARG A NH1 1 
ATOM   604  N NH2 . ARG A 1 73  ? -19.16158 25.06827 -20.82199 1.000 32.00736  ? 73  ARG A NH2 1 
ATOM   605  N N   A LEU A 1 74  ? -13.65727 26.31175 -24.30928 0.420 26.58024  ? 74  LEU A N   1 
ATOM   606  N N   B LEU A 1 74  ? -13.66614 26.28990 -24.29432 0.580 28.31552  ? 74  LEU A N   1 
ATOM   607  C CA  A LEU A 1 74  ? -12.56888 26.77035 -23.45133 0.420 26.35663  ? 74  LEU A CA  1 
ATOM   608  C CA  B LEU A 1 74  ? -12.56219 26.76987 -23.47025 0.580 29.90930  ? 74  LEU A CA  1 
ATOM   609  C C   A LEU A 1 74  ? -12.16981 28.19991 -23.79617 0.420 27.63941  ? 74  LEU A C   1 
ATOM   610  C C   B LEU A 1 74  ? -12.21809 28.21635 -23.80498 0.580 29.96377  ? 74  LEU A C   1 
ATOM   611  O O   A LEU A 1 74  ? -11.98810 29.03845 -22.90514 0.420 26.78507  ? 74  LEU A O   1 
ATOM   612  O O   B LEU A 1 74  ? -12.15700 29.07417 -22.91693 0.580 30.06586  ? 74  LEU A O   1 
ATOM   613  C CB  A LEU A 1 74  ? -11.37330 25.82867 -23.59127 0.420 27.67244  ? 74  LEU A CB  1 
ATOM   614  C CB  B LEU A 1 74  ? -11.34890 25.85901 -23.66328 0.580 35.79562  ? 74  LEU A CB  1 
ATOM   615  C CG  A LEU A 1 74  ? -11.39462 24.53878 -22.78044 0.420 26.90112  ? 74  LEU A CG  1 
ATOM   616  C CG  B LEU A 1 74  ? -10.30964 25.74264 -22.55838 0.580 39.54702  ? 74  LEU A CG  1 
ATOM   617  C CD1 A LEU A 1 74  ? -10.24999 23.64410 -23.21513 0.420 31.34656  ? 74  LEU A CD1 1 
ATOM   618  C CD1 B LEU A 1 74  ? -10.81768 24.90309 -21.39316 0.580 41.84574  ? 74  LEU A CD1 1 
ATOM   619  C CD2 A LEU A 1 74  ? -11.31415 24.82054 -21.28953 0.420 31.16760  ? 74  LEU A CD2 1 
ATOM   620  C CD2 B LEU A 1 74  ? -9.02968  25.14589 -23.13609 0.580 40.62478  ? 74  LEU A CD2 1 
ATOM   621  N N   A LEU A 1 75  ? -12.03139 28.49727 -25.09049 0.420 28.16902  ? 75  LEU A N   1 
ATOM   622  N N   B LEU A 1 75  ? -12.00799 28.51020 -25.09103 0.580 29.28921  ? 75  LEU A N   1 
ATOM   623  C CA  A LEU A 1 75  ? -11.62851 29.83989 -25.50026 0.420 29.38613  ? 75  LEU A CA  1 
ATOM   624  C CA  B LEU A 1 75  ? -11.61483 29.86059 -25.48844 0.580 29.27981  ? 75  LEU A CA  1 
ATOM   625  C C   A LEU A 1 75  ? -12.70335 30.86597 -25.16693 0.420 28.54176  ? 75  LEU A C   1 
ATOM   626  C C   B LEU A 1 75  ? -12.70570 30.88099 -25.18635 0.580 28.86698  ? 75  LEU A C   1 
ATOM   627  O O   A LEU A 1 75  ? -12.39057 31.99633 -24.77718 0.420 27.92228  ? 75  LEU A O   1 
ATOM   628  O O   B LEU A 1 75  ? -12.40256 32.02875 -24.84358 0.580 28.71464  ? 75  LEU A O   1 
ATOM   629  C CB  A LEU A 1 75  ? -11.30473 29.86259 -26.99546 0.420 29.28834  ? 75  LEU A CB  1 
ATOM   630  C CB  B LEU A 1 75  ? -11.25315 29.88513 -26.97582 0.580 26.78797  ? 75  LEU A CB  1 
ATOM   631  C CG  A LEU A 1 75  ? -9.88205  29.44703 -27.37820 0.420 32.84167  ? 75  LEU A CG  1 
ATOM   632  C CG  B LEU A 1 75  ? -9.98031  29.12017 -27.34623 0.580 27.19589  ? 75  LEU A CG  1 
ATOM   633  C CD1 A LEU A 1 75  ? -9.34149  28.40850 -26.42280 0.420 35.23658  ? 75  LEU A CD1 1 
ATOM   634  C CD1 B LEU A 1 75  ? -9.84522  29.04496 -28.85563 0.580 29.42497  ? 75  LEU A CD1 1 
ATOM   635  C CD2 A LEU A 1 75  ? -9.82532  28.94903 -28.81514 0.420 33.17874  ? 75  LEU A CD2 1 
ATOM   636  C CD2 B LEU A 1 75  ? -8.74866  29.78718 -26.74599 0.580 27.49531  ? 75  LEU A CD2 1 
ATOM   637  N N   . LYS A 1 76  ? -13.97552 30.49446 -25.31096 1.000 26.38321  ? 76  LYS A N   1 
ATOM   638  C CA  . LYS A 1 76  ? -15.04462 31.42045 -24.95411 1.000 22.73169  ? 76  LYS A CA  1 
ATOM   639  C C   . LYS A 1 76  ? -15.05376 31.72999 -23.46078 1.000 29.39049  ? 76  LYS A C   1 
ATOM   640  O O   . LYS A 1 76  ? -15.48584 32.82001 -23.06758 1.000 30.75892  ? 76  LYS A O   1 
ATOM   641  C CB  . LYS A 1 76  ? -16.40617 30.86719 -25.40636 1.000 24.21488  ? 76  LYS A CB  1 
ATOM   642  C CG  . LYS A 1 76  ? -16.68187 31.05896 -26.92299 1.000 26.67737  ? 76  LYS A CG  1 
ATOM   643  C CD  . LYS A 1 76  ? -18.09137 30.54433 -27.29370 1.000 27.69564  ? 76  LYS A CD  1 
ATOM   644  C CE  . LYS A 1 76  ? -19.19007 31.41579 -26.69378 1.000 28.23461  ? 76  LYS A CE  1 
ATOM   645  N NZ  . LYS A 1 76  ? -20.55278 31.10684 -27.22070 1.000 28.69669  ? 76  LYS A NZ  1 
ATOM   646  N N   . HIS A 1 77  ? -14.55113 30.83422 -22.61764 1.000 27.28145  ? 77  HIS A N   1 
ATOM   647  C CA  . HIS A 1 77  ? -14.65379 31.08296 -21.18670 1.000 28.66999  ? 77  HIS A CA  1 
ATOM   648  C C   . HIS A 1 77  ? -13.54026 31.95929 -20.64730 1.000 27.15650  ? 77  HIS A C   1 
ATOM   649  O O   . HIS A 1 77  ? -13.74494 32.65151 -19.64193 1.000 28.90292  ? 77  HIS A O   1 
ATOM   650  C CB  . HIS A 1 77  ? -14.66896 29.75250 -20.42469 1.000 28.86670  ? 77  HIS A CB  1 
ATOM   651  C CG  . HIS A 1 77  ? -15.12581 29.87636 -19.00640 1.000 34.01459  ? 77  HIS A CG  1 
ATOM   652  N ND1 . HIS A 1 77  ? -16.45712 29.94511 -18.66478 1.000 36.97278  ? 77  HIS A ND1 1 
ATOM   653  C CD2 . HIS A 1 77  ? -14.43584 29.87433 -17.83938 1.000 35.52852  ? 77  HIS A CD2 1 
ATOM   654  C CE1 . HIS A 1 77  ? -16.56596 30.03379 -17.34850 1.000 38.39104  ? 77  HIS A CE1 1 
ATOM   655  N NE2 . HIS A 1 77  ? -15.35409 29.98437 -16.82304 1.000 38.58417  ? 77  HIS A NE2 1 
ATOM   656  N N   . MET A 1 78  ? -12.36580 31.92926 -21.27509 1.000 28.30866  ? 78  MET A N   1 
ATOM   657  C CA  . MET A 1 78  ? -11.13006 32.45101 -20.68790 1.000 30.20602  ? 78  MET A CA  1 
ATOM   658  C C   . MET A 1 78  ? -11.13043 33.97056 -20.77182 1.000 32.65746  ? 78  MET A C   1 
ATOM   659  O O   . MET A 1 78  ? -10.92846 34.52384 -21.85359 1.000 35.29214  ? 78  MET A O   1 
ATOM   660  C CB  . MET A 1 78  ? -9.93712  31.89116 -21.46408 1.000 33.63252  ? 78  MET A CB  1 
ATOM   661  C CG  . MET A 1 78  ? -9.45068  30.51654 -21.13487 1.000 38.90993  ? 78  MET A CG  1 
ATOM   662  S SD  . MET A 1 78  ? -9.49745  29.97726 -19.43869 1.000 39.58642  ? 78  MET A SD  1 
ATOM   663  C CE  . MET A 1 78  ? -9.10295  28.25605 -19.68222 1.000 45.97673  ? 78  MET A CE  1 
ATOM   664  N N   . LYS A 1 79  ? -11.29407 34.65885 -19.63636 1.000 32.52209  ? 79  LYS A N   1 
ATOM   665  C CA  . LYS A 1 79  ? -11.33689 36.13036 -19.61348 1.000 28.69576  ? 79  LYS A CA  1 
ATOM   666  C C   . LYS A 1 79  ? -10.42980 36.61420 -18.47540 1.000 32.17815  ? 79  LYS A C   1 
ATOM   667  O O   . LYS A 1 79  ? -10.89879 36.87974 -17.35588 1.000 31.33064  ? 79  LYS A O   1 
ATOM   668  C CB  . LYS A 1 79  ? -12.79018 36.62028 -19.43920 1.000 32.16747  ? 79  LYS A CB  1 
ATOM   669  C CG  . LYS A 1 79  ? -13.59038 36.64490 -20.71445 1.000 43.18859  ? 79  LYS A CG  1 
ATOM   670  C CD  . LYS A 1 79  ? -15.02251 36.21280 -20.45250 1.000 52.13847  ? 79  LYS A CD  1 
ATOM   671  C CE  . LYS A 1 79  ? -15.78500 35.98155 -21.73825 1.000 56.36194  ? 79  LYS A CE  1 
ATOM   672  N NZ  . LYS A 1 79  ? -16.68930 37.11082 -22.09031 1.000 60.56780  ? 79  LYS A NZ  1 
ATOM   673  N N   . HIS A 1 80  ? -9.13007  36.71022 -18.76726 1.000 31.47330  ? 80  HIS A N   1 
ATOM   674  C CA  . HIS A 1 80  ? -8.09770  37.01048 -17.78414 1.000 28.95707  ? 80  HIS A CA  1 
ATOM   675  C C   . HIS A 1 80  ? -6.89863  37.63813 -18.49016 1.000 28.75167  ? 80  HIS A C   1 
ATOM   676  O O   . HIS A 1 80  ? -6.55681  37.23214 -19.60198 1.000 32.60991  ? 80  HIS A O   1 
ATOM   677  C CB  . HIS A 1 80  ? -7.66168  35.73192 -17.03642 1.000 29.45094  ? 80  HIS A CB  1 
ATOM   678  C CG  . HIS A 1 80  ? -6.74489  35.97612 -15.87541 1.000 33.23339  ? 80  HIS A CG  1 
ATOM   679  N ND1 . HIS A 1 80  ? -5.37438  36.09814 -16.02040 1.000 28.33584  ? 80  HIS A ND1 1 
ATOM   680  C CD2 . HIS A 1 80  ? -6.99638  36.09724 -14.55001 1.000 32.79586  ? 80  HIS A CD2 1 
ATOM   681  C CE1 . HIS A 1 80  ? -4.82375  36.28481 -14.83566 1.000 30.10905  ? 80  HIS A CE1 1 
ATOM   682  N NE2 . HIS A 1 80  ? -5.78730  36.30848 -13.92459 1.000 30.64272  ? 80  HIS A NE2 1 
ATOM   683  N N   . GLU A 1 81  ? -6.25687  38.61364 -17.82758 1.000 27.30942  ? 81  GLU A N   1 
ATOM   684  C CA  . GLU A 1 81  ? -5.12544  39.32247 -18.43882 1.000 29.48081  ? 81  GLU A CA  1 
ATOM   685  C C   . GLU A 1 81  ? -3.98535  38.39095 -18.83121 1.000 30.04289  ? 81  GLU A C   1 
ATOM   686  O O   . GLU A 1 81  ? -3.22993  38.70024 -19.76362 1.000 31.60195  ? 81  GLU A O   1 
ATOM   687  C CB  . GLU A 1 81  ? -4.58274  40.39784 -17.49614 1.000 36.05577  ? 81  GLU A CB  1 
ATOM   688  C CG  . GLU A 1 81  ? -5.58919  41.46196 -17.06291 1.000 43.87042  ? 81  GLU A CG  1 
ATOM   689  C CD  . GLU A 1 81  ? -4.92659  42.58482 -16.26866 1.000 59.34798  ? 81  GLU A CD  1 
ATOM   690  O OE1 . GLU A 1 81  ? -3.85576  42.33918 -15.66194 1.000 60.08098  ? 81  GLU A OE1 1 
ATOM   691  O OE2 . GLU A 1 81  ? -5.44714  43.72418 -16.28913 1.000 61.90733  ? 81  GLU A OE2 1 
ATOM   692  N N   . ASN A 1 82  ? -3.80365  37.28238 -18.11241 1.000 27.60651  ? 82  ASN A N   1 
ATOM   693  C CA  . ASN A 1 82  ? -2.65367  36.40498 -18.34021 1.000 26.64286  ? 82  ASN A CA  1 
ATOM   694  C C   . ASN A 1 82  ? -3.02638  35.12209 -19.07628 1.000 27.82839  ? 82  ASN A C   1 
ATOM   695  O O   . ASN A 1 82  ? -2.24323  34.15855 -19.06707 1.000 28.96470  ? 82  ASN A O   1 
ATOM   696  C CB  . ASN A 1 82  ? -1.94102  36.06141 -17.02412 1.000 30.86931  ? 82  ASN A CB  1 
ATOM   697  C CG  . ASN A 1 82  ? -1.47537  37.29530 -16.27183 1.000 30.85791  ? 82  ASN A CG  1 
ATOM   698  O OD1 . ASN A 1 82  ? -1.92528  37.56786 -15.14644 1.000 30.03973  ? 82  ASN A OD1 1 
ATOM   699  N ND2 . ASN A 1 82  ? -0.57593  38.06828 -16.90113 1.000 30.04564  ? 82  ASN A ND2 1 
ATOM   700  N N   . VAL A 1 83  ? -4.17440  35.10300 -19.75095 1.000 26.98005  ? 83  VAL A N   1 
ATOM   701  C CA  . VAL A 1 83  ? -4.61108  33.93567 -20.51158 1.000 27.18522  ? 83  VAL A CA  1 
ATOM   702  C C   . VAL A 1 83  ? -5.15645  34.43396 -21.83473 1.000 30.09228  ? 83  VAL A C   1 
ATOM   703  O O   . VAL A 1 83  ? -5.89215  35.42338 -21.86996 1.000 29.49035  ? 83  VAL A O   1 
ATOM   704  C CB  . VAL A 1 83  ? -5.69856  33.13684 -19.76267 1.000 29.08944  ? 83  VAL A CB  1 
ATOM   705  C CG1 . VAL A 1 83  ? -6.07001  31.88458 -20.54719 1.000 29.03839  ? 83  VAL A CG1 1 
ATOM   706  C CG2 . VAL A 1 83  ? -5.26485  32.82378 -18.29672 1.000 27.61182  ? 83  VAL A CG2 1 
ATOM   707  N N   . ILE A 1 84  ? -4.80627  33.75077 -22.92301 1.000 30.74162  ? 84  ILE A N   1 
ATOM   708  C CA  . ILE A 1 84  ? -5.33528  34.12526 -24.22476 1.000 36.99276  ? 84  ILE A CA  1 
ATOM   709  C C   . ILE A 1 84  ? -6.83894  33.92247 -24.24206 1.000 38.63459  ? 84  ILE A C   1 
ATOM   710  O O   . ILE A 1 84  ? -7.34407  32.87782 -23.82381 1.000 39.77955  ? 84  ILE A O   1 
ATOM   711  C CB  . ILE A 1 84  ? -4.64541  33.33178 -25.34026 1.000 42.80612  ? 84  ILE A CB  1 
ATOM   712  C CG1 . ILE A 1 84  ? -4.94143  33.99363 -26.67879 1.000 42.07126  ? 84  ILE A CG1 1 
ATOM   713  C CG2 . ILE A 1 84  ? -5.11351  31.87984 -25.32551 1.000 46.74246  ? 84  ILE A CG2 1 
ATOM   714  C CD1 . ILE A 1 84  ? -4.03315  35.20496 -26.96576 1.000 49.40579  ? 84  ILE A CD1 1 
ATOM   715  N N   . GLY A 1 85  ? -7.56284  34.93168 -24.71920 1.000 36.86761  ? 85  GLY A N   1 
ATOM   716  C CA  . GLY A 1 85  ? -8.99402  34.85492 -24.88600 1.000 37.66174  ? 85  GLY A CA  1 
ATOM   717  C C   . GLY A 1 85  ? -9.38742  34.83673 -26.35592 1.000 33.88260  ? 85  GLY A C   1 
ATOM   718  O O   . GLY A 1 85  ? -8.56182  34.87634 -27.26123 1.000 40.09534  ? 85  GLY A O   1 
ATOM   719  N N   A LEU A 1 86  ? -10.69689 34.76929 -26.56949 0.300 32.43816  ? 86  LEU A N   1 
ATOM   720  N N   B LEU A 1 86  ? -10.69262 34.78660 -26.57813 0.700 30.51213  ? 86  LEU A N   1 
ATOM   721  C CA  A LEU A 1 86  ? -11.27294 34.75821 -27.90828 0.300 30.89944  ? 86  LEU A CA  1 
ATOM   722  C CA  B LEU A 1 86  ? -11.25466 34.73751 -27.92347 0.700 28.75975  ? 86  LEU A CA  1 
ATOM   723  C C   A LEU A 1 86  ? -11.68710 36.17301 -28.29559 0.300 29.85529  ? 86  LEU A C   1 
ATOM   724  C C   B LEU A 1 86  ? -11.74010 36.12462 -28.34055 0.700 27.63592  ? 86  LEU A C   1 
ATOM   725  O O   A LEU A 1 86  ? -12.48913 36.80248 -27.59952 0.300 29.94532  ? 86  LEU A O   1 
ATOM   726  O O   B LEU A 1 86  ? -12.65068 36.68237 -27.71762 0.700 29.37191  ? 86  LEU A O   1 
ATOM   727  C CB  A LEU A 1 86  ? -12.47706 33.81809 -27.96766 0.300 30.21060  ? 86  LEU A CB  1 
ATOM   728  C CB  B LEU A 1 86  ? -12.40001 33.72626 -27.98465 0.700 27.52470  ? 86  LEU A CB  1 
ATOM   729  C CG  A LEU A 1 86  ? -12.32503 32.52907 -28.77660 0.300 31.85360  ? 86  LEU A CG  1 
ATOM   730  C CG  B LEU A 1 86  ? -12.93946 33.38174 -29.37610 0.700 26.78335  ? 86  LEU A CG  1 
ATOM   731  C CD1 A LEU A 1 86  ? -13.68744 31.94052 -29.08925 0.300 29.60140  ? 86  LEU A CD1 1 
ATOM   732  C CD1 B LEU A 1 86  ? -11.86222 32.75769 -30.26919 0.700 28.75776  ? 86  LEU A CD1 1 
ATOM   733  C CD2 A LEU A 1 86  ? -11.53015 32.78389 -30.05579 0.300 32.37181  ? 86  LEU A CD2 1 
ATOM   734  C CD2 B LEU A 1 86  ? -14.12876 32.45076 -29.22808 0.700 31.69549  ? 86  LEU A CD2 1 
ATOM   735  N N   . LEU A 1 87  ? -11.14057 36.67201 -29.40296 1.000 29.97857  ? 87  LEU A N   1 
ATOM   736  C CA  . LEU A 1 87  ? -11.58818 37.96059 -29.93247 1.000 29.49132  ? 87  LEU A CA  1 
ATOM   737  C C   . LEU A 1 87  ? -12.82281 37.82178 -30.81844 1.000 28.95621  ? 87  LEU A C   1 
ATOM   738  O O   . LEU A 1 87  ? -13.66735 38.72117 -30.84979 1.000 29.37738  ? 87  LEU A O   1 
ATOM   739  C CB  . LEU A 1 87  ? -10.46041 38.62704 -30.72411 1.000 30.18667  ? 87  LEU A CB  1 
ATOM   740  C CG  . LEU A 1 87  ? -9.28051  39.12941 -29.90185 1.000 32.33214  ? 87  LEU A CG  1 
ATOM   741  C CD1 . LEU A 1 87  ? -8.22693  39.67128 -30.84852 1.000 34.57982  ? 87  LEU A CD1 1 
ATOM   742  C CD2 . LEU A 1 87  ? -9.74189  40.22736 -28.94289 1.000 36.87268  ? 87  LEU A CD2 1 
ATOM   743  N N   . ASP A 1 88  ? -12.92696 36.72374 -31.55662 1.000 27.82064  ? 88  ASP A N   1 
ATOM   744  C CA  . ASP A 1 88  ? -13.98709 36.52481 -32.53676 1.000 27.46607  ? 88  ASP A CA  1 
ATOM   745  C C   . ASP A 1 88  ? -14.01007 35.06074 -32.91863 1.000 27.00938  ? 88  ASP A C   1 
ATOM   746  O O   . ASP A 1 88  ? -12.99842 34.36614 -32.81015 1.000 27.24329  ? 88  ASP A O   1 
ATOM   747  C CB  . ASP A 1 88  ? -13.78052 37.38139 -33.79783 1.000 30.12065  ? 88  ASP A CB  1 
ATOM   748  C CG  . ASP A 1 88  ? -15.07962 37.60994 -34.58759 1.000 34.05860  ? 88  ASP A CG  1 
ATOM   749  O OD1 . ASP A 1 88  ? -16.17023 37.23834 -34.09152 1.000 33.21588  ? 88  ASP A OD1 1 
ATOM   750  O OD2 . ASP A 1 88  ? -14.99467 38.10947 -35.75375 1.000 31.38495  ? 88  ASP A OD2 1 
ATOM   751  N N   . VAL A 1 89  ? -15.17720 34.59559 -33.34397 1.000 26.75203  ? 89  VAL A N   1 
ATOM   752  C CA  . VAL A 1 89  ? -15.30539 33.29543 -33.99084 1.000 29.06177  ? 89  VAL A CA  1 
ATOM   753  C C   . VAL A 1 89  ? -16.38230 33.45285 -35.04369 1.000 31.54016  ? 89  VAL A C   1 
ATOM   754  O O   . VAL A 1 89  ? -17.41593 34.07800 -34.78654 1.000 34.12380  ? 89  VAL A O   1 
ATOM   755  C CB  . VAL A 1 89  ? -15.65815 32.17146 -32.98831 1.000 29.21956  ? 89  VAL A CB  1 
ATOM   756  C CG1 . VAL A 1 89  ? -16.82520 32.58454 -32.07838 1.000 30.16619  ? 89  VAL A CG1 1 
ATOM   757  C CG2 . VAL A 1 89  ? -15.97674 30.84900 -33.72716 1.000 29.50824  ? 89  VAL A CG2 1 
ATOM   758  N N   . PHE A 1 90  ? -16.14882 32.90384 -36.23422 1.000 29.48834  ? 90  PHE A N   1 
ATOM   759  C CA  . PHE A 1 90  ? -17.14389 33.08721 -37.28142 1.000 30.22459  ? 90  PHE A CA  1 
ATOM   760  C C   . PHE A 1 90  ? -17.15584 31.87739 -38.20563 1.000 28.98052  ? 90  PHE A C   1 
ATOM   761  O O   . PHE A 1 90  ? -16.23371 31.05400 -38.20571 1.000 28.82908  ? 90  PHE A O   1 
ATOM   762  C CB  . PHE A 1 90  ? -16.90433 34.39256 -38.05178 1.000 30.71581  ? 90  PHE A CB  1 
ATOM   763  C CG  . PHE A 1 90  ? -15.56587 34.46771 -38.74484 1.000 34.75017  ? 90  PHE A CG  1 
ATOM   764  C CD1 . PHE A 1 90  ? -15.36472 33.82741 -39.96122 1.000 32.36404  ? 90  PHE A CD1 1 
ATOM   765  C CD2 . PHE A 1 90  ? -14.50572 35.18323 -38.18007 1.000 35.74421  ? 90  PHE A CD2 1 
ATOM   766  C CE1 . PHE A 1 90  ? -14.12405 33.90109 -40.62180 1.000 32.66136  ? 90  PHE A CE1 1 
ATOM   767  C CE2 . PHE A 1 90  ? -13.26524 35.26147 -38.82330 1.000 32.30545  ? 90  PHE A CE2 1 
ATOM   768  C CZ  . PHE A 1 90  ? -13.07555 34.62054 -40.06245 1.000 33.30105  ? 90  PHE A CZ  1 
ATOM   769  N N   . THR A 1 91  ? -18.23291 31.77323 -38.98424 1.000 29.61699  ? 91  THR A N   1 
ATOM   770  C CA  . THR A 1 91  ? -18.35259 30.80071 -40.06089 1.000 33.24803  ? 91  THR A CA  1 
ATOM   771  C C   . THR A 1 91  ? -19.03109 31.50015 -41.22928 1.000 33.86821  ? 91  THR A C   1 
ATOM   772  O O   . THR A 1 91  ? -19.91606 32.33870 -41.01515 1.000 34.29477  ? 91  THR A O   1 
ATOM   773  C CB  . THR A 1 91  ? -19.17050 29.55839 -39.66413 1.000 34.57530  ? 91  THR A CB  1 
ATOM   774  O OG1 . THR A 1 91  ? -19.28234 28.67637 -40.78438 1.000 37.80916  ? 91  THR A OG1 1 
ATOM   775  C CG2 . THR A 1 91  ? -20.58743 29.94098 -39.23054 1.000 30.62641  ? 91  THR A CG2 1 
ATOM   776  N N   . PRO A 1 92  ? -18.64016 31.18972 -42.46658 1.000 36.57373  ? 92  PRO A N   1 
ATOM   777  C CA  . PRO A 1 92  ? -19.36550 31.75091 -43.61738 1.000 38.97154  ? 92  PRO A CA  1 
ATOM   778  C C   . PRO A 1 92  ? -20.72159 31.11061 -43.82760 1.000 38.35549  ? 92  PRO A C   1 
ATOM   779  O O   . PRO A 1 92  ? -21.53862 31.66407 -44.57843 1.000 40.80465  ? 92  PRO A O   1 
ATOM   780  C CB  . PRO A 1 92  ? -18.42843 31.47408 -44.80409 1.000 39.52940  ? 92  PRO A CB  1 
ATOM   781  C CG  . PRO A 1 92  ? -17.57958 30.31649 -44.36264 1.000 41.03688  ? 92  PRO A CG  1 
ATOM   782  C CD  . PRO A 1 92  ? -17.42807 30.45012 -42.86517 1.000 40.02463  ? 92  PRO A CD  1 
ATOM   783  N N   . ALA A 1 93  ? -20.98701 29.96716 -43.19675 1.000 36.49085  ? 93  ALA A N   1 
ATOM   784  C CA  . ALA A 1 93  ? -22.26313 29.29423 -43.39737 1.000 38.13353  ? 93  ALA A CA  1 
ATOM   785  C C   . ALA A 1 93  ? -23.40813 30.15917 -42.88496 1.000 41.01603  ? 93  ALA A C   1 
ATOM   786  O O   . ALA A 1 93  ? -23.25965 30.92847 -41.93248 1.000 42.88428  ? 93  ALA A O   1 
ATOM   787  C CB  . ALA A 1 93  ? -22.26492 27.93757 -42.69540 1.000 39.42899  ? 93  ALA A CB  1 
ATOM   788  N N   . ARG A 1 94  ? -24.56360 30.03303 -43.52931 1.000 44.07979  ? 94  ARG A N   1 
ATOM   789  C CA  . ARG A 1 94  ? -25.72799 30.83308 -43.18121 1.000 45.81217  ? 94  ARG A CA  1 
ATOM   790  C C   . ARG A 1 94  ? -26.75509 30.02821 -42.39266 1.000 45.62247  ? 94  ARG A C   1 
ATOM   791  O O   . ARG A 1 94  ? -27.77312 30.57972 -41.96950 1.000 47.33002  ? 94  ARG A O   1 
ATOM   792  C CB  . ARG A 1 94  ? -26.34941 31.41916 -44.45882 1.000 51.12003  ? 94  ARG A CB  1 
ATOM   793  C CG  . ARG A 1 94  ? -25.52264 32.58982 -45.00150 1.000 56.11605  ? 94  ARG A CG  1 
ATOM   794  C CD  . ARG A 1 94  ? -25.88927 33.08370 -46.40456 1.000 64.38100  ? 94  ARG A CD  1 
ATOM   795  N NE  . ARG A 1 94  ? -26.11409 34.52824 -46.41860 1.000 73.05127  ? 94  ARG A NE  1 
ATOM   796  C CZ  . ARG A 1 94  ? -25.71774 35.34632 -47.38778 1.000 77.28107  ? 94  ARG A CZ  1 
ATOM   797  N NH1 . ARG A 1 94  ? -25.03041 34.90500 -48.43011 1.000 80.04562  ? 94  ARG A NH1 1 
ATOM   798  N NH2 . ARG A 1 94  ? -25.99371 36.64515 -47.29491 1.000 75.22857  ? 94  ARG A NH2 1 
ATOM   799  N N   . SER A 1 95  ? -26.48296 28.74978 -42.15265 1.000 46.15741  ? 95  SER A N   1 
ATOM   800  C CA  . SER A 1 95  ? -27.41351 27.83761 -41.50335 1.000 45.54224  ? 95  SER A CA  1 
ATOM   801  C C   . SER A 1 95  ? -26.62473 26.64142 -40.99669 1.000 43.55039  ? 95  SER A C   1 
ATOM   802  O O   . SER A 1 95  ? -25.51618 26.37287 -41.46345 1.000 42.63767  ? 95  SER A O   1 
ATOM   803  C CB  . SER A 1 95  ? -28.50506 27.38366 -42.47165 1.000 44.19260  ? 95  SER A CB  1 
ATOM   804  O OG  . SER A 1 95  ? -27.94786 26.53445 -43.46513 1.000 48.89065  ? 95  SER A OG  1 
ATOM   805  N N   . LEU A 1 96  ? -27.21707 25.90707 -40.04635 1.000 42.71442  ? 96  LEU A N   1 
ATOM   806  C CA  . LEU A 1 96  ? -26.57083 24.68680 -39.57549 1.000 44.26151  ? 96  LEU A CA  1 
ATOM   807  C C   . LEU A 1 96  ? -26.34216 23.68904 -40.71291 1.000 46.90515  ? 96  LEU A C   1 
ATOM   808  O O   . LEU A 1 96  ? -25.32548 22.98463 -40.72260 1.000 48.76346  ? 96  LEU A O   1 
ATOM   809  C CB  . LEU A 1 96  ? -27.38511 24.06114 -38.43141 1.000 47.20617  ? 96  LEU A CB  1 
ATOM   810  C CG  . LEU A 1 96  ? -26.95524 22.67355 -37.93881 1.000 44.44191  ? 96  LEU A CG  1 
ATOM   811  C CD1 . LEU A 1 96  ? -25.61430 22.75363 -37.24068 1.000 43.62247  ? 96  LEU A CD1 1 
ATOM   812  C CD2 . LEU A 1 96  ? -27.98506 22.11178 -36.94273 1.000 41.25956  ? 96  LEU A CD2 1 
ATOM   813  N N   . GLU A 1 97  ? -27.24711 23.63835 -41.69526 1.000 48.52846  ? 97  GLU A N   1 
ATOM   814  C CA  . GLU A 1 97  ? -27.14140 22.63813 -42.75793 1.000 50.82778  ? 97  GLU A CA  1 
ATOM   815  C C   . GLU A 1 97  ? -25.91801 22.85245 -43.63945 1.000 51.25669  ? 97  GLU A C   1 
ATOM   816  O O   . GLU A 1 97  ? -25.38847 21.88790 -44.20455 1.000 56.34038  ? 97  GLU A O   1 
ATOM   817  C CB  . GLU A 1 97  ? -28.41520 22.63335 -43.60781 1.000 55.96525  ? 97  GLU A CB  1 
ATOM   818  C CG  . GLU A 1 97  ? -29.67642 22.26360 -42.83040 1.000 69.09934  ? 97  GLU A CG  1 
ATOM   819  C CD  . GLU A 1 97  ? -30.08015 23.30992 -41.79503 1.000 76.67782  ? 97  GLU A CD  1 
ATOM   820  O OE1 . GLU A 1 97  ? -29.83371 24.51437 -42.02339 1.000 79.74506  ? 97  GLU A OE1 1 
ATOM   821  O OE2 . GLU A 1 97  ? -30.62436 22.91972 -40.73778 1.000 76.94699  ? 97  GLU A OE2 1 
ATOM   822  N N   . GLU A 1 98  ? -25.45766 24.09194 -43.78415 1.000 48.55154  ? 98  GLU A N   1 
ATOM   823  C CA  . GLU A 1 98  ? -24.25967 24.37700 -44.56499 1.000 51.14262  ? 98  GLU A CA  1 
ATOM   824  C C   . GLU A 1 98  ? -23.03574 24.65784 -43.68857 1.000 47.99560  ? 98  GLU A C   1 
ATOM   825  O O   . GLU A 1 98  ? -22.00775 25.11241 -44.19687 1.000 47.90017  ? 98  GLU A O   1 
ATOM   826  C CB  . GLU A 1 98  ? -24.54794 25.53249 -45.53633 1.000 54.78387  ? 98  GLU A CB  1 
ATOM   827  C CG  . GLU A 1 98  ? -24.79458 26.88964 -44.89030 1.000 58.28338  ? 98  GLU A CG  1 
ATOM   828  C CD  . GLU A 1 98  ? -25.19117 27.96084 -45.90653 1.000 65.15239  ? 98  GLU A CD  1 
ATOM   829  O OE1 . GLU A 1 98  ? -26.27471 27.81584 -46.51410 1.000 72.42740  ? 98  GLU A OE1 1 
ATOM   830  O OE2 . GLU A 1 98  ? -24.43897 28.94044 -46.10357 1.000 62.19059  ? 98  GLU A OE2 1 
ATOM   831  N N   . PHE A 1 99  ? -23.10925 24.35232 -42.39258 1.000 43.39810  ? 99  PHE A N   1 
ATOM   832  C CA  . PHE A 1 99  ? -22.02538 24.62675 -41.45399 1.000 41.00024  ? 99  PHE A CA  1 
ATOM   833  C C   . PHE A 1 99  ? -20.92781 23.57629 -41.60190 1.000 41.52705  ? 99  PHE A C   1 
ATOM   834  O O   . PHE A 1 99  ? -21.13975 22.39743 -41.30024 1.000 44.33739  ? 99  PHE A O   1 
ATOM   835  C CB  . PHE A 1 99  ? -22.59716 24.65647 -40.03771 1.000 40.53083  ? 99  PHE A CB  1 
ATOM   836  C CG  . PHE A 1 99  ? -21.58826 24.91261 -38.96342 1.000 38.33857  ? 99  PHE A CG  1 
ATOM   837  C CD1 . PHE A 1 99  ? -20.69400 25.97291 -39.05303 1.000 36.24412  ? 99  PHE A CD1 1 
ATOM   838  C CD2 . PHE A 1 99  ? -21.57349 24.11492 -37.81628 1.000 36.72082  ? 99  PHE A CD2 1 
ATOM   839  C CE1 . PHE A 1 99  ? -19.77513 26.20656 -38.03039 1.000 35.84346  ? 99  PHE A CE1 1 
ATOM   840  C CE2 . PHE A 1 99  ? -20.67422 24.34357 -36.79633 1.000 34.45744  ? 99  PHE A CE2 1 
ATOM   841  C CZ  . PHE A 1 99  ? -19.76876 25.39062 -36.89772 1.000 37.02928  ? 99  PHE A CZ  1 
ATOM   842  N N   . ASN A 1 100 ? -19.74451 24.00313 -42.04320 1.000 43.69621  ? 100 ASN A N   1 
ATOM   843  C CA  . ASN A 1 100 ? -18.60670 23.09886 -42.19865 1.000 44.57153  ? 100 ASN A CA  1 
ATOM   844  C C   . ASN A 1 100 ? -17.27732 23.69091 -41.75993 1.000 42.56846  ? 100 ASN A C   1 
ATOM   845  O O   . ASN A 1 100 ? -16.32468 22.93047 -41.56580 1.000 48.28278  ? 100 ASN A O   1 
ATOM   846  C CB  . ASN A 1 100 ? -18.46775 22.64111 -43.66123 1.000 52.79749  ? 100 ASN A CB  1 
ATOM   847  C CG  . ASN A 1 100 ? -19.66691 21.84110 -44.14391 1.000 63.09167  ? 100 ASN A CG  1 
ATOM   848  O OD1 . ASN A 1 100 ? -20.04434 20.84285 -43.52851 1.000 71.26679  ? 100 ASN A OD1 1 
ATOM   849  N ND2 . ASN A 1 100 ? -20.25899 22.26482 -45.26041 1.000 62.17328  ? 100 ASN A ND2 1 
ATOM   850  N N   . ASP A 1 101 ? -17.16936 24.99853 -41.58309 1.000 37.16216  ? 101 ASP A N   1 
ATOM   851  C CA  . ASP A 1 101 ? -15.88917 25.63289 -41.32386 1.000 37.65658  ? 101 ASP A CA  1 
ATOM   852  C C   . ASP A 1 101 ? -15.98426 26.51637 -40.08995 1.000 37.04648  ? 101 ASP A C   1 
ATOM   853  O O   . ASP A 1 101 ? -17.01473 27.15203 -39.84207 1.000 37.43907  ? 101 ASP A O   1 
ATOM   854  C CB  . ASP A 1 101 ? -15.45105 26.45948 -42.54230 1.000 44.70387  ? 101 ASP A CB  1 
ATOM   855  C CG  . ASP A 1 101 ? -14.79726 25.60704 -43.62460 1.000 53.74014  ? 101 ASP A CG  1 
ATOM   856  O OD1 . ASP A 1 101 ? -14.34000 24.48298 -43.32549 1.000 58.55561  ? 101 ASP A OD1 1 
ATOM   857  O OD2 . ASP A 1 101 ? -14.77658 26.05023 -44.78438 1.000 57.79962  ? 101 ASP A OD2 1 
ATOM   858  N N   . VAL A 1 102 ? -14.90674 26.54135 -39.31221 1.000 37.04740  ? 102 VAL A N   1 
ATOM   859  C CA  . VAL A 1 102 ? -14.81844 27.32570 -38.08558 1.000 34.81223  ? 102 VAL A CA  1 
ATOM   860  C C   . VAL A 1 102 ? -13.52639 28.12014 -38.10594 1.000 32.35784  ? 102 VAL A C   1 
ATOM   861  O O   . VAL A 1 102 ? -12.45220 27.55630 -38.34937 1.000 36.01610  ? 102 VAL A O   1 
ATOM   862  C CB  . VAL A 1 102 ? -14.86106 26.44860 -36.82411 1.000 37.22781  ? 102 VAL A CB  1 
ATOM   863  C CG1 . VAL A 1 102 ? -14.97118 27.34480 -35.62239 1.000 39.30107  ? 102 VAL A CG1 1 
ATOM   864  C CG2 . VAL A 1 102 ? -16.05796 25.51195 -36.85808 1.000 39.95723  ? 102 VAL A CG2 1 
ATOM   865  N N   . TYR A 1 103 ? -13.62999 29.42010 -37.83512 1.000 27.24054  ? 103 TYR A N   1 
ATOM   866  C CA  . TYR A 1 103 ? -12.47846 30.30595 -37.75445 1.000 26.91902  ? 103 TYR A CA  1 
ATOM   867  C C   . TYR A 1 103 ? -12.43164 30.93688 -36.36818 1.000 27.48204  ? 103 TYR A C   1 
ATOM   868  O O   . TYR A 1 103 ? -13.44895 31.42405 -35.86997 1.000 30.15436  ? 103 TYR A O   1 
ATOM   869  C CB  . TYR A 1 103 ? -12.54931 31.41596 -38.80555 1.000 30.66422  ? 103 TYR A CB  1 
ATOM   870  C CG  . TYR A 1 103 ? -12.53486 31.00311 -40.26724 1.000 31.26095  ? 103 TYR A CG  1 
ATOM   871  C CD1 . TYR A 1 103 ? -13.66457 30.45414 -40.88675 1.000 28.43026  ? 103 TYR A CD1 1 
ATOM   872  C CD2 . TYR A 1 103 ? -11.39408 31.21318 -41.04467 1.000 28.73912  ? 103 TYR A CD2 1 
ATOM   873  C CE1 . TYR A 1 103 ? -13.64222 30.10333 -42.24314 1.000 33.68268  ? 103 TYR A CE1 1 
ATOM   874  C CE2 . TYR A 1 103 ? -11.36617 30.86718 -42.39828 1.000 29.93115  ? 103 TYR A CE2 1 
ATOM   875  C CZ  . TYR A 1 103 ? -12.49259 30.32482 -42.98936 1.000 33.10649  ? 103 TYR A CZ  1 
ATOM   876  O OH  . TYR A 1 103 ? -12.42632 29.99560 -44.32550 1.000 35.65120  ? 103 TYR A OH  1 
ATOM   877  N N   . LEU A 1 104 ? -11.24587 30.93900 -35.75182 1.000 26.80159  ? 104 LEU A N   1 
ATOM   878  C CA  . LEU A 1 104 ? -11.03016 31.51621 -34.42981 1.000 29.65146  ? 104 LEU A CA  1 
ATOM   879  C C   . LEU A 1 104 ? -10.06293 32.68239 -34.56136 1.000 30.74302  ? 104 LEU A C   1 
ATOM   880  O O   . LEU A 1 104 ? -9.05023  32.57767 -35.26099 1.000 32.32960  ? 104 LEU A O   1 
ATOM   881  C CB  . LEU A 1 104 ? -10.45521 30.46843 -33.47462 1.000 29.27670  ? 104 LEU A CB  1 
ATOM   882  C CG  . LEU A 1 104 ? -11.27111 29.18680 -33.37078 1.000 28.11723  ? 104 LEU A CG  1 
ATOM   883  C CD1 . LEU A 1 104 ? -10.45537 28.12947 -32.63574 1.000 31.76322  ? 104 LEU A CD1 1 
ATOM   884  C CD2 . LEU A 1 104 ? -12.60526 29.46787 -32.66525 1.000 30.37720  ? 104 LEU A CD2 1 
ATOM   885  N N   . VAL A 1 105 ? -10.36762 33.78935 -33.87835 1.000 27.50498  ? 105 VAL A N   1 
ATOM   886  C CA  . VAL A 1 105 ? -9.56083  35.00332 -33.95510 1.000 27.44271  ? 105 VAL A CA  1 
ATOM   887  C C   . VAL A 1 105 ? -9.03121  35.32743 -32.55687 1.000 32.84069  ? 105 VAL A C   1 
ATOM   888  O O   . VAL A 1 105 ? -9.80891  35.46851 -31.60816 1.000 28.90552  ? 105 VAL A O   1 
ATOM   889  C CB  . VAL A 1 105 ? -10.37885 36.16730 -34.52798 1.000 25.66540  ? 105 VAL A CB  1 
ATOM   890  C CG1 . VAL A 1 105 ? -9.49979  37.43450 -34.66731 1.000 29.77869  ? 105 VAL A CG1 1 
ATOM   891  C CG2 . VAL A 1 105 ? -10.98931 35.77413 -35.86416 1.000 27.49856  ? 105 VAL A CG2 1 
ATOM   892  N N   . THR A 1 106 ? -7.71097  35.44967 -32.43105 1.000 31.25014  ? 106 THR A N   1 
ATOM   893  C CA  . THR A 1 106 ? -7.05986  35.78444 -31.17180 1.000 29.30551  ? 106 THR A CA  1 
ATOM   894  C C   . THR A 1 106 ? -6.00467  36.85040 -31.40742 1.000 32.92864  ? 106 THR A C   1 
ATOM   895  O O   . THR A 1 106 ? -5.64401  37.16024 -32.54401 1.000 34.27062  ? 106 THR A O   1 
ATOM   896  C CB  . THR A 1 106 ? -6.40575  34.55480 -30.53374 1.000 32.23227  ? 106 THR A CB  1 
ATOM   897  O OG1 . THR A 1 106 ? -5.38250  34.06096 -31.41544 1.000 34.98989  ? 106 THR A OG1 1 
ATOM   898  C CG2 . THR A 1 106 ? -7.43579  33.48691 -30.21434 1.000 31.50236  ? 106 THR A CG2 1 
ATOM   899  N N   . HIS A 1 107 ? -5.53098  37.43015 -30.30863 1.000 36.78974  ? 107 HIS A N   1 
ATOM   900  C CA  . HIS A 1 107 ? -4.47374  38.42462 -30.39906 1.000 39.51409  ? 107 HIS A CA  1 
ATOM   901  C C   . HIS A 1 107 ? -3.25974  37.81600 -31.08406 1.000 40.58600  ? 107 HIS A C   1 
ATOM   902  O O   . HIS A 1 107 ? -2.85012  36.70272 -30.74959 1.000 39.16360  ? 107 HIS A O   1 
ATOM   903  C CB  . HIS A 1 107 ? -4.07858  38.92829 -29.01056 1.000 43.62111  ? 107 HIS A CB  1 
ATOM   904  C CG  . HIS A 1 107 ? -4.98223  39.98725 -28.45664 1.000 49.06102  ? 107 HIS A CG  1 
ATOM   905  N ND1 . HIS A 1 107 ? -5.02516  41.26747 -28.96630 1.000 53.29831  ? 107 HIS A ND1 1 
ATOM   906  C CD2 . HIS A 1 107 ? -5.80176  39.98751 -27.37626 1.000 56.02007  ? 107 HIS A CD2 1 
ATOM   907  C CE1 . HIS A 1 107 ? -5.88123  41.99158 -28.26590 1.000 54.07177  ? 107 HIS A CE1 1 
ATOM   908  N NE2 . HIS A 1 107 ? -6.35983  41.24213 -27.28946 1.000 54.99111  ? 107 HIS A NE2 1 
ATOM   909  N N   . LEU A 1 108 ? -2.66548  38.55562 -32.02712 1.000 40.40639  ? 108 LEU A N   1 
ATOM   910  C CA  . LEU A 1 108 ? -1.43322  38.10078 -32.66259 1.000 41.11066  ? 108 LEU A CA  1 
ATOM   911  C C   . LEU A 1 108 ? -0.29182  38.19626 -31.67039 1.000 46.17716  ? 108 LEU A C   1 
ATOM   912  O O   . LEU A 1 108 ? 0.05236   39.28427 -31.20081 1.000 48.42053  ? 108 LEU A O   1 
ATOM   913  C CB  . LEU A 1 108 ? -1.12238  38.91240 -33.91667 1.000 42.31702  ? 108 LEU A CB  1 
ATOM   914  C CG  . LEU A 1 108 ? 0.11627   38.45236 -34.69282 1.000 45.03215  ? 108 LEU A CG  1 
ATOM   915  C CD1 . LEU A 1 108 ? -0.05176  37.05092 -35.27261 1.000 42.40131  ? 108 LEU A CD1 1 
ATOM   916  C CD2 . LEU A 1 108 ? 0.42940   39.44825 -35.80347 1.000 46.25519  ? 108 LEU A CD2 1 
ATOM   917  N N   . MET A 1 109 ? 0.28658   37.05913 -31.34741 1.000 48.71273  ? 109 MET A N   1 
ATOM   918  C CA  . MET A 1 109 ? 1.29876   36.98781 -30.31328 1.000 56.03525  ? 109 MET A CA  1 
ATOM   919  C C   . MET A 1 109 ? 2.64361   36.93748 -31.02587 1.000 60.72718  ? 109 MET A C   1 
ATOM   920  O O   . MET A 1 109 ? 2.78308   36.25195 -32.04463 1.000 61.08557  ? 109 MET A O   1 
ATOM   921  C CB  . MET A 1 109 ? 1.06418   35.75098 -29.44843 1.000 65.91341  ? 109 MET A CB  1 
ATOM   922  C CG  . MET A 1 109 ? -0.12384  35.90627 -28.47138 1.000 71.06612  ? 109 MET A CG  1 
ATOM   923  S SD  . MET A 1 109 ? -0.05635  37.17935 -27.18980 1.000 71.19874  ? 109 MET A SD  1 
ATOM   924  C CE  . MET A 1 109 ? -1.16117  38.42991 -27.82009 1.000 72.29953  ? 109 MET A CE  1 
ATOM   925  N N   . GLY A 1 110 ? 3.60755   37.70560 -30.53593 1.000 60.15703  ? 110 GLY A N   1 
ATOM   926  C CA  . GLY A 1 110 ? 4.90568   37.73253 -31.17810 1.000 61.65657  ? 110 GLY A CA  1 
ATOM   927  C C   . GLY A 1 110 ? 5.87134   36.74926 -30.55300 1.000 60.66760  ? 110 GLY A C   1 
ATOM   928  O O   . GLY A 1 110 ? 5.90535   35.56820 -30.91958 1.000 61.66869  ? 110 GLY A O   1 
ATOM   929  N N   . ALA A 1 111 ? 6.64936   37.22527 -29.58780 1.000 55.35275  ? 111 ALA A N   1 
ATOM   930  C CA  . ALA A 1 111 ? 7.67156   36.39733 -28.97581 1.000 50.13716  ? 111 ALA A CA  1 
ATOM   931  C C   . ALA A 1 111 ? 7.06997   35.49487 -27.90743 1.000 47.31508  ? 111 ALA A C   1 
ATOM   932  O O   . ALA A 1 111 ? 6.02686   35.79129 -27.31925 1.000 45.96875  ? 111 ALA A O   1 
ATOM   933  C CB  . ALA A 1 111 ? 8.76874   37.26852 -28.36807 1.000 49.32883  ? 111 ALA A CB  1 
ATOM   934  N N   . ASP A 1 112 ? 7.72941   34.36951 -27.67890 1.000 43.59201  ? 112 ASP A N   1 
ATOM   935  C CA  . ASP A 1 112 ? 7.38949   33.48022 -26.58580 1.000 41.12645  ? 112 ASP A CA  1 
ATOM   936  C C   . ASP A 1 112 ? 8.57283   33.40312 -25.63098 1.000 44.09372  ? 112 ASP A C   1 
ATOM   937  O O   . ASP A 1 112 ? 9.63805   33.97208 -25.88330 1.000 50.65588  ? 112 ASP A O   1 
ATOM   938  C CB  . ASP A 1 112 ? 6.97082   32.10284 -27.11878 1.000 41.72738  ? 112 ASP A CB  1 
ATOM   939  C CG  . ASP A 1 112 ? 8.10713   31.34850 -27.77041 1.000 50.94705  ? 112 ASP A CG  1 
ATOM   940  O OD1 . ASP A 1 112 ? 9.28837   31.65418 -27.50020 1.000 53.52940  ? 112 ASP A OD1 1 
ATOM   941  O OD2 . ASP A 1 112 ? 7.80964   30.46677 -28.59852 1.000 53.45539  ? 112 ASP A OD2 1 
ATOM   942  N N   . LEU A 1 113 ? 8.36822   32.70111 -24.51349 1.000 42.84047  ? 113 LEU A N   1 
ATOM   943  C CA  . LEU A 1 113 ? 9.40136   32.61725 -23.49068 1.000 43.34188  ? 113 LEU A CA  1 
ATOM   944  C C   . LEU A 1 113 ? 10.70282  32.04461 -24.03571 1.000 49.56590  ? 113 LEU A C   1 
ATOM   945  O O   . LEU A 1 113 ? 11.76915  32.33802 -23.48780 1.000 53.59344  ? 113 LEU A O   1 
ATOM   946  C CB  . LEU A 1 113 ? 8.91592   31.77313 -22.31021 1.000 45.82299  ? 113 LEU A CB  1 
ATOM   947  C CG  . LEU A 1 113 ? 9.44669   32.12634 -20.91524 1.000 47.04429  ? 113 LEU A CG  1 
ATOM   948  C CD1 . LEU A 1 113 ? 9.43474   33.63108 -20.66496 1.000 47.63825  ? 113 LEU A CD1 1 
ATOM   949  C CD2 . LEU A 1 113 ? 8.69536   31.39023 -19.83093 1.000 44.86258  ? 113 LEU A CD2 1 
ATOM   950  N N   . ASN A 1 114 ? 10.63908  31.23892 -25.09950 1.000 55.08553  ? 114 ASN A N   1 
ATOM   951  C CA  . ASN A 1 114 ? 11.85841  30.74712 -25.73711 1.000 64.76406  ? 114 ASN A CA  1 
ATOM   952  C C   . ASN A 1 114 ? 12.68439  31.88984 -26.31621 1.000 73.18988  ? 114 ASN A C   1 
ATOM   953  O O   . ASN A 1 114 ? 13.91160  31.91683 -26.15949 1.000 77.54218  ? 114 ASN A O   1 
ATOM   954  C CB  . ASN A 1 114 ? 11.50044  29.73228 -26.82330 1.000 67.83060  ? 114 ASN A CB  1 
ATOM   955  C CG  . ASN A 1 114 ? 11.49913  28.30452 -26.31175 1.000 68.70449  ? 114 ASN A CG  1 
ATOM   956  O OD1 . ASN A 1 114 ? 11.86020  28.03961 -25.16323 1.000 64.21656  ? 114 ASN A OD1 1 
ATOM   957  N ND2 . ASN A 1 114 ? 11.05535  27.37803 -27.15388 1.000 71.40180  ? 114 ASN A ND2 1 
ATOM   958  N N   . ASN A 1 115 ? 12.03276  32.84394 -26.99278 1.000 75.56798  ? 115 ASN A N   1 
ATOM   959  C CA  . ASN A 1 115 ? 12.72333  33.99755 -27.55611 1.000 78.35754  ? 115 ASN A CA  1 
ATOM   960  C C   . ASN A 1 115 ? 13.16958  34.99105 -26.49572 1.000 86.00890  ? 115 ASN A C   1 
ATOM   961  O O   . ASN A 1 115 ? 13.42289  36.15407 -26.82845 1.000 87.82507  ? 115 ASN A O   1 
ATOM   962  C CB  . ASN A 1 115 ? 11.84699  34.70825 -28.58962 1.000 76.25757  ? 115 ASN A CB  1 
ATOM   963  C CG  . ASN A 1 115 ? 11.14412  33.74717 -29.50928 1.000 76.94802  ? 115 ASN A CG  1 
ATOM   964  O OD1 . ASN A 1 115 ? 9.92001   33.78089 -29.66106 1.000 73.30189  ? 115 ASN A OD1 1 
ATOM   965  N ND2 . ASN A 1 115 ? 11.91690  32.85459 -30.11388 1.000 78.26490  ? 115 ASN A ND2 1 
ATOM   966  N N   . ILE A 1 116 ? 13.27234  34.55655 -25.23815 1.000 91.72438  ? 116 ILE A N   1 
ATOM   967  C CA  . ILE A 1 116 ? 13.71124  35.40613 -24.13546 1.000 95.44727  ? 116 ILE A CA  1 
ATOM   968  C C   . ILE A 1 116 ? 14.79668  34.70140 -23.32356 1.000 100.81773 ? 116 ILE A C   1 
ATOM   969  O O   . ILE A 1 116 ? 15.72946  35.34576 -22.82930 1.000 104.54782 ? 116 ILE A O   1 
ATOM   970  C CB  . ILE A 1 116 ? 12.52643  35.80396 -23.23105 1.000 92.18104  ? 116 ILE A CB  1 
ATOM   971  C CG1 . ILE A 1 116 ? 11.37530  36.38813 -24.05062 1.000 90.46986  ? 116 ILE A CG1 1 
ATOM   972  C CG2 . ILE A 1 116 ? 12.96621  36.80945 -22.17919 1.000 91.32061  ? 116 ILE A CG2 1 
ATOM   973  C CD1 . ILE A 1 116 ? 11.80589  37.42226 -25.06474 1.000 91.54412  ? 116 ILE A CD1 1 
ATOM   974  N N   . VAL A 1 117 ? 14.69328  33.37487 -23.18216 1.000 101.97189 ? 117 VAL A N   1 
ATOM   975  C CA  . VAL A 1 117 ? 15.58143  32.66596 -22.25965 1.000 105.25156 ? 117 VAL A CA  1 
ATOM   976  C C   . VAL A 1 117 ? 17.01382  32.64734 -22.78186 1.000 111.85279 ? 117 VAL A C   1 
ATOM   977  O O   . VAL A 1 117 ? 17.96603  32.84821 -22.01797 1.000 113.85995 ? 117 VAL A O   1 
ATOM   978  C CB  . VAL A 1 117 ? 15.06677  31.24117 -21.97257 1.000 101.10548 ? 117 VAL A CB  1 
ATOM   979  C CG1 . VAL A 1 117 ? 15.07755  30.39083 -23.23371 1.000 103.72688 ? 117 VAL A CG1 1 
ATOM   980  C CG2 . VAL A 1 117 ? 15.90922  30.58478 -20.86825 1.000 94.69114  ? 117 VAL A CG2 1 
ATOM   981  N N   . LYS A 1 118 ? 17.20156  32.39876 -24.07365 1.000 115.29357 ? 118 LYS A N   1 
ATOM   982  C CA  . LYS A 1 118 ? 18.54119  32.38494 -24.65942 1.000 116.90365 ? 118 LYS A CA  1 
ATOM   983  C C   . LYS A 1 118 ? 18.74384  33.65788 -25.47957 1.000 125.14373 ? 118 LYS A C   1 
ATOM   984  O O   . LYS A 1 118 ? 18.71763  33.65903 -26.71443 1.000 125.28376 ? 118 LYS A O   1 
ATOM   985  C CB  . LYS A 1 118 ? 18.77046  31.10533 -25.49219 1.000 108.07880 ? 118 LYS A CB  1 
ATOM   986  C CG  . LYS A 1 118 ? 19.57940  30.04237 -24.73130 1.000 98.83517  ? 118 LYS A CG  1 
ATOM   987  C CD  . LYS A 1 118 ? 21.09563  30.26167 -24.82769 1.000 90.31165  ? 118 LYS A CD  1 
ATOM   988  C CE  . LYS A 1 118 ? 21.82840  29.15988 -25.61731 1.000 81.69102  ? 118 LYS A CE  1 
ATOM   989  N NZ  . LYS A 1 118 ? 20.99966  28.42129 -26.61988 1.000 78.11844  ? 118 LYS A NZ  1 
ATOM   990  N N   . CYS A 1 119 ? 18.93513  34.76215 -24.75154 1.000 130.23353 ? 119 CYS A N   1 
ATOM   991  C CA  . CYS A 1 119 ? 19.32862  36.06239 -25.28672 1.000 131.24645 ? 119 CYS A CA  1 
ATOM   992  C C   . CYS A 1 119 ? 19.69399  36.96802 -24.11552 1.000 127.71104 ? 119 CYS A C   1 
ATOM   993  O O   . CYS A 1 119 ? 20.82942  37.44615 -24.01170 1.000 128.39233 ? 119 CYS A O   1 
ATOM   994  C CB  . CYS A 1 119 ? 18.21099  36.69321 -26.12639 1.000 134.02332 ? 119 CYS A CB  1 
ATOM   995  S SG  . CYS A 1 119 ? 17.04875  37.75565 -25.20297 1.000 135.85301 ? 119 CYS A SG  1 
ATOM   996  N N   . GLN A 1 120 ? 18.73022  37.19077 -23.22458 1.000 121.91082 ? 120 GLN A N   1 
ATOM   997  C CA  . GLN A 1 120 ? 18.92564  37.95570 -22.00250 1.000 115.57423 ? 120 GLN A CA  1 
ATOM   998  C C   . GLN A 1 120 ? 19.45379  37.04090 -20.90307 1.000 115.38947 ? 120 GLN A C   1 
ATOM   999  O O   . GLN A 1 120 ? 19.18621  35.83565 -20.89547 1.000 114.91370 ? 120 GLN A O   1 
ATOM   1000 C CB  . GLN A 1 120 ? 17.60329  38.58265 -21.54894 1.000 109.71281 ? 120 GLN A CB  1 
ATOM   1001 C CG  . GLN A 1 120 ? 17.29686  39.95797 -22.11894 1.000 104.96234 ? 120 GLN A CG  1 
ATOM   1002 C CD  . GLN A 1 120 ? 15.80096  40.20575 -22.24135 1.000 101.89206 ? 120 GLN A CD  1 
ATOM   1003 O OE1 . GLN A 1 120 ? 15.16011  40.69640 -21.30869 1.000 99.18782  ? 120 GLN A OE1 1 
ATOM   1004 N NE2 . GLN A 1 120 ? 15.23469  39.84841 -23.39051 1.000 102.24957 ? 120 GLN A NE2 1 
ATOM   1005 N N   . LYS A 1 121 ? 20.21185  37.61914 -19.96768 1.000 115.21772 ? 121 LYS A N   1 
ATOM   1006 C CA  . LYS A 1 121 ? 20.51062  36.88178 -18.74543 1.000 112.59740 ? 121 LYS A CA  1 
ATOM   1007 C C   . LYS A 1 121 ? 19.33732  36.88471 -17.77661 1.000 108.83726 ? 121 LYS A C   1 
ATOM   1008 O O   . LYS A 1 121 ? 19.35706  36.11918 -16.80693 1.000 112.84777 ? 121 LYS A O   1 
ATOM   1009 C CB  . LYS A 1 121 ? 21.75242  37.44330 -18.03529 1.000 111.97114 ? 121 LYS A CB  1 
ATOM   1010 C CG  . LYS A 1 121 ? 23.08557  36.87034 -18.52675 1.000 110.73128 ? 121 LYS A CG  1 
ATOM   1011 C CD  . LYS A 1 121 ? 23.65551  35.78610 -17.59654 1.000 108.96386 ? 121 LYS A CD  1 
ATOM   1012 C CE  . LYS A 1 121 ? 24.04263  36.31130 -16.21878 1.000 106.83387 ? 121 LYS A CE  1 
ATOM   1013 N NZ  . LYS A 1 121 ? 23.93105  35.24511 -15.17652 1.000 104.92495 ? 121 LYS A NZ  1 
ATOM   1014 N N   . LEU A 1 122 ? 18.31952  37.71261 -18.03154 1.000 99.37728  ? 122 LEU A N   1 
ATOM   1015 C CA  . LEU A 1 122 ? 17.16568  37.88037 -17.15190 1.000 87.99088  ? 122 LEU A CA  1 
ATOM   1016 C C   . LEU A 1 122 ? 17.55880  38.13864 -15.70424 1.000 78.50233  ? 122 LEU A C   1 
ATOM   1017 O O   . LEU A 1 122 ? 18.17390  37.29514 -15.04355 1.000 78.93397  ? 122 LEU A O   1 
ATOM   1018 C CB  . LEU A 1 122 ? 16.23154  36.67069 -17.23379 1.000 85.43094  ? 122 LEU A CB  1 
ATOM   1019 C CG  . LEU A 1 122 ? 15.49800  36.52212 -18.56606 1.000 84.46645  ? 122 LEU A CG  1 
ATOM   1020 C CD1 . LEU A 1 122 ? 14.43197  35.44638 -18.47644 1.000 85.03227  ? 122 LEU A CD1 1 
ATOM   1021 C CD2 . LEU A 1 122 ? 14.87342  37.85367 -18.96276 1.000 82.35556  ? 122 LEU A CD2 1 
ATOM   1022 N N   . THR A 1 123 ? 17.19276  39.30936 -15.20424 1.000 68.04359  ? 123 THR A N   1 
ATOM   1023 C CA  . THR A 1 123 ? 17.40450  39.60962 -13.80354 1.000 61.35378  ? 123 THR A CA  1 
ATOM   1024 C C   . THR A 1 123 ? 16.42643  38.81333 -12.93881 1.000 57.08302  ? 123 THR A C   1 
ATOM   1025 O O   . THR A 1 123 ? 15.40373  38.30846 -13.40953 1.000 51.22426  ? 123 THR A O   1 
ATOM   1026 C CB  . THR A 1 123 ? 17.27009  41.11671 -13.56798 1.000 62.83828  ? 123 THR A CB  1 
ATOM   1027 O OG1 . THR A 1 123 ? 15.88927  41.47591 -13.46556 1.000 56.81167  ? 123 THR A OG1 1 
ATOM   1028 C CG2 . THR A 1 123 ? 17.90439  41.89569 -14.71654 1.000 67.44985  ? 123 THR A CG2 1 
ATOM   1029 N N   . ASP A 1 124 ? 16.76899  38.67376 -11.65664 1.000 56.06738  ? 124 ASP A N   1 
ATOM   1030 C CA  . ASP A 1 124 ? 15.84956  38.00685 -10.73817 1.000 51.22206  ? 124 ASP A CA  1 
ATOM   1031 C C   . ASP A 1 124 ? 14.51559  38.73475 -10.68349 1.000 44.54283  ? 124 ASP A C   1 
ATOM   1032 O O   . ASP A 1 124 ? 13.47741  38.09782 -10.48418 1.000 42.89784  ? 124 ASP A O   1 
ATOM   1033 C CB  . ASP A 1 124 ? 16.47973  37.89141 -9.34231  1.000 48.02230  ? 124 ASP A CB  1 
ATOM   1034 C CG  . ASP A 1 124 ? 15.63716  37.07011 -8.36804  1.000 47.61734  ? 124 ASP A CG  1 
ATOM   1035 O OD1 . ASP A 1 124 ? 15.32784  35.88042 -8.64775  1.000 43.45027  ? 124 ASP A OD1 1 
ATOM   1036 O OD2 . ASP A 1 124 ? 15.30692  37.61182 -7.28883  1.000 46.42627  ? 124 ASP A OD2 1 
ATOM   1037 N N   . ASP A 1 125 ? 14.51661  40.06034 -10.87738 1.000 45.42029  ? 125 ASP A N   1 
ATOM   1038 C CA  . ASP A 1 125 ? 13.25402  40.79336 -10.92490 1.000 45.95945  ? 125 ASP A CA  1 
ATOM   1039 C C   . ASP A 1 125 ? 12.42010  40.39191 -12.13391 1.000 41.16893  ? 125 ASP A C   1 
ATOM   1040 O O   . ASP A 1 125 ? 11.19805  40.27328 -12.03007 1.000 40.71823  ? 125 ASP A O   1 
ATOM   1041 C CB  . ASP A 1 125 ? 13.50147  42.29891 -10.93293 1.000 62.97081  ? 125 ASP A CB  1 
ATOM   1042 C CG  . ASP A 1 125 ? 14.19190  42.77545 -9.67718  1.000 77.21657  ? 125 ASP A CG  1 
ATOM   1043 O OD1 . ASP A 1 125 ? 13.48589  43.06950 -8.68513  1.000 80.38136  ? 125 ASP A OD1 1 
ATOM   1044 O OD2 . ASP A 1 125 ? 15.43855  42.85223 -9.68129  1.000 83.45906  ? 125 ASP A OD2 1 
ATOM   1045 N N   . HIS A 1 126 ? 13.05188  40.20101 -13.29285 1.000 41.40595  ? 126 HIS A N   1 
ATOM   1046 C CA  . HIS A 1 126 ? 12.30241  39.70673 -14.44538 1.000 43.73207  ? 126 HIS A CA  1 
ATOM   1047 C C   . HIS A 1 126 ? 11.74400  38.30689 -14.18748 1.000 37.26772  ? 126 HIS A C   1 
ATOM   1048 O O   . HIS A 1 126 ? 10.58855  38.01763 -14.52259 1.000 36.61443  ? 126 HIS A O   1 
ATOM   1049 C CB  . HIS A 1 126 ? 13.17914  39.72888 -15.70097 1.000 51.96851  ? 126 HIS A CB  1 
ATOM   1050 C CG  . HIS A 1 126 ? 13.45317  41.10791 -16.22792 1.000 65.10328  ? 126 HIS A CG  1 
ATOM   1051 N ND1 . HIS A 1 126 ? 14.70555  41.51450 -16.63609 1.000 68.33193  ? 126 HIS A ND1 1 
ATOM   1052 C CD2 . HIS A 1 126 ? 12.63211  42.16677 -16.43022 1.000 68.64944  ? 126 HIS A CD2 1 
ATOM   1053 C CE1 . HIS A 1 126 ? 14.64714  42.76507 -17.05632 1.000 69.96238  ? 126 HIS A CE1 1 
ATOM   1054 N NE2 . HIS A 1 126 ? 13.39952  43.18378 -16.94494 1.000 70.41769  ? 126 HIS A NE2 1 
ATOM   1055 N N   . VAL A 1 127 ? 12.54399  37.42136 -13.59899 1.000 33.40436  ? 127 VAL A N   1 
ATOM   1056 C CA  . VAL A 1 127 ? 12.03787  36.08438 -13.29541 1.000 29.82270  ? 127 VAL A CA  1 
ATOM   1057 C C   . VAL A 1 127 ? 10.83528  36.16561 -12.36273 1.000 31.89022  ? 127 VAL A C   1 
ATOM   1058 O O   . VAL A 1 127 ? 9.82102   35.48815 -12.57145 1.000 32.37886  ? 127 VAL A O   1 
ATOM   1059 C CB  . VAL A 1 127 ? 13.14621  35.20040 -12.69944 1.000 31.86810  ? 127 VAL A CB  1 
ATOM   1060 C CG1 . VAL A 1 127 ? 12.57516  33.85657 -12.29414 1.000 32.03464  ? 127 VAL A CG1 1 
ATOM   1061 C CG2 . VAL A 1 127 ? 14.28177  35.00031 -13.70703 1.000 33.89096  ? 127 VAL A CG2 1 
ATOM   1062 N N   . GLN A 1 128 ? 10.93614  36.97812 -11.30903 1.000 31.29783  ? 128 GLN A N   1 
ATOM   1063 C CA  . GLN A 1 128 ? 9.81350   37.16602 -10.38166 1.000 30.81942  ? 128 GLN A CA  1 
ATOM   1064 C C   . GLN A 1 128 ? 8.53504   37.54103 -11.12282 1.000 29.64670  ? 128 GLN A C   1 
ATOM   1065 O O   . GLN A 1 128 ? 7.46381   36.96628 -10.88178 1.000 29.60768  ? 128 GLN A O   1 
ATOM   1066 C CB  . GLN A 1 128 ? 10.14922  38.25902 -9.36382  1.000 32.10693  ? 128 GLN A CB  1 
ATOM   1067 C CG  . GLN A 1 128 ? 11.23612  37.93580 -8.39488  1.000 39.05644  ? 128 GLN A CG  1 
ATOM   1068 C CD  . GLN A 1 128 ? 11.42475  39.06688 -7.39894  1.000 47.14490  ? 128 GLN A CD  1 
ATOM   1069 O OE1 . GLN A 1 128 ? 10.55045  39.92510 -7.24349  1.000 46.37970  ? 128 GLN A OE1 1 
ATOM   1070 N NE2 . GLN A 1 128 ? 12.56994  39.07604 -6.72148  1.000 49.01061  ? 128 GLN A NE2 1 
ATOM   1071 N N   . PHE A 1 129 ? 8.62966   38.54398 -12.00297 1.000 34.15382  ? 129 PHE A N   1 
ATOM   1072 C CA  . PHE A 1 129 ? 7.45220   39.06338 -12.69398 1.000 32.68085  ? 129 PHE A CA  1 
ATOM   1073 C C   . PHE A 1 129 ? 6.88141   38.04168 -13.66208 1.000 30.04156  ? 129 PHE A C   1 
ATOM   1074 O O   . PHE A 1 129 ? 5.65722   37.86070 -13.73948 1.000 29.50487  ? 129 PHE A O   1 
ATOM   1075 C CB  . PHE A 1 129 ? 7.80899   40.37283 -13.41590 1.000 32.71566  ? 129 PHE A CB  1 
ATOM   1076 C CG  . PHE A 1 129 ? 6.62723   41.07668 -14.02704 1.000 35.59621  ? 129 PHE A CG  1 
ATOM   1077 C CD1 . PHE A 1 129 ? 5.47683   41.31054 -13.28737 1.000 41.00163  ? 129 PHE A CD1 1 
ATOM   1078 C CD2 . PHE A 1 129 ? 6.69445   41.56846 -15.32118 1.000 33.80831  ? 129 PHE A CD2 1 
ATOM   1079 C CE1 . PHE A 1 129 ? 4.38872   41.96226 -13.84791 1.000 41.97160  ? 129 PHE A CE1 1 
ATOM   1080 C CE2 . PHE A 1 129 ? 5.60747   42.24548 -15.89285 1.000 37.11027  ? 129 PHE A CE2 1 
ATOM   1081 C CZ  . PHE A 1 129 ? 4.45524   42.43869 -15.15210 1.000 37.85064  ? 129 PHE A CZ  1 
ATOM   1082 N N   . LEU A 1 130 ? 7.74792   37.36456 -14.41037 1.000 28.68712  ? 130 LEU A N   1 
ATOM   1083 C CA  . LEU A 1 130 ? 7.27846   36.37041 -15.36579 1.000 27.12641  ? 130 LEU A CA  1 
ATOM   1084 C C   . LEU A 1 130 ? 6.58784   35.21114 -14.65468 1.000 28.21644  ? 130 LEU A C   1 
ATOM   1085 O O   . LEU A 1 130 ? 5.48369   34.79685 -15.04000 1.000 28.09206  ? 130 LEU A O   1 
ATOM   1086 C CB  . LEU A 1 130 ? 8.46450   35.88371 -16.20412 1.000 29.30446  ? 130 LEU A CB  1 
ATOM   1087 C CG  . LEU A 1 130 ? 8.98597   36.85660 -17.27270 1.000 34.04872  ? 130 LEU A CG  1 
ATOM   1088 C CD1 . LEU A 1 130 ? 10.19990  36.27082 -17.98724 1.000 35.25376  ? 130 LEU A CD1 1 
ATOM   1089 C CD2 . LEU A 1 130 ? 7.90052   37.20721 -18.30318 1.000 36.56778  ? 130 LEU A CD2 1 
ATOM   1090 N N   . ILE A 1 131 ? 7.21735   34.66415 -13.60807 1.000 30.30269  ? 131 ILE A N   1 
ATOM   1091 C CA  . ILE A 1 131 ? 6.59255   33.52882 -12.93139 1.000 28.38876  ? 131 ILE A CA  1 
ATOM   1092 C C   . ILE A 1 131 ? 5.33009   33.97235 -12.19590 1.000 27.54087  ? 131 ILE A C   1 
ATOM   1093 O O   . ILE A 1 131 ? 4.34642   33.23053 -12.13403 1.000 26.46070  ? 131 ILE A O   1 
ATOM   1094 C CB  . ILE A 1 131 ? 7.59412   32.82627 -11.99532 1.000 27.24424  ? 131 ILE A CB  1 
ATOM   1095 C CG1 . ILE A 1 131 ? 8.82271   32.38708 -12.80277 1.000 27.80743  ? 131 ILE A CG1 1 
ATOM   1096 C CG2 . ILE A 1 131 ? 6.94509   31.60480 -11.30097 1.000 26.48922  ? 131 ILE A CG2 1 
ATOM   1097 C CD1 . ILE A 1 131 ? 8.53433   31.35462 -13.89982 1.000 28.88398  ? 131 ILE A CD1 1 
ATOM   1098 N N   . TYR A 1 132 ? 5.33167   35.19398 -11.64167 1.000 27.54226  ? 132 TYR A N   1 
ATOM   1099 C CA  . TYR A 1 132 ? 4.14279   35.71184 -10.98113 1.000 28.59602  ? 132 TYR A CA  1 
ATOM   1100 C C   . TYR A 1 132 ? 2.94371   35.70077 -11.92076 1.000 27.26132  ? 132 TYR A C   1 
ATOM   1101 O O   . TYR A 1 132 ? 1.82501   35.31737 -11.52848 1.000 28.34706  ? 132 TYR A O   1 
ATOM   1102 C CB  . TYR A 1 132 ? 4.40894   37.13050 -10.46032 1.000 28.51070  ? 132 TYR A CB  1 
ATOM   1103 C CG  . TYR A 1 132 ? 3.13965   37.77952 -9.95847  1.000 30.42302  ? 132 TYR A CG  1 
ATOM   1104 C CD1 . TYR A 1 132 ? 2.60183   37.43397 -8.71936  1.000 30.83576  ? 132 TYR A CD1 1 
ATOM   1105 C CD2 . TYR A 1 132 ? 2.46345   38.70907 -10.72521 1.000 32.18668  ? 132 TYR A CD2 1 
ATOM   1106 C CE1 . TYR A 1 132 ? 1.42062   38.00627 -8.26545  1.000 30.40779  ? 132 TYR A CE1 1 
ATOM   1107 C CE2 . TYR A 1 132 ? 1.28072   39.27736 -10.27999 1.000 31.84482  ? 132 TYR A CE2 1 
ATOM   1108 C CZ  . TYR A 1 132 ? 0.77398   38.92528 -9.04646  1.000 34.01993  ? 132 TYR A CZ  1 
ATOM   1109 O OH  . TYR A 1 132 ? -0.40496  39.47634 -8.58529  1.000 38.97339  ? 132 TYR A OH  1 
ATOM   1110 N N   . GLN A 1 133 ? 3.15824   36.10831 -13.16916 1.000 28.46312  ? 133 GLN A N   1 
ATOM   1111 C CA  . GLN A 1 133 ? 2.06573   36.17680 -14.13172 1.000 28.95474  ? 133 GLN A CA  1 
ATOM   1112 C C   . GLN A 1 133 ? 1.58333   34.78627 -14.52689 1.000 28.80336  ? 133 GLN A C   1 
ATOM   1113 O O   . GLN A 1 133 ? 0.37373   34.56409 -14.65741 1.000 28.80119  ? 133 GLN A O   1 
ATOM   1114 C CB  . GLN A 1 133 ? 2.50856   36.96018 -15.36512 1.000 25.25497  ? 133 GLN A CB  1 
ATOM   1115 C CG  . GLN A 1 133 ? 2.79085   38.41375 -15.10101 1.000 26.56773  ? 133 GLN A CG  1 
ATOM   1116 C CD  . GLN A 1 133 ? 3.29731   39.08722 -16.33700 1.000 31.68220  ? 133 GLN A CD  1 
ATOM   1117 O OE1 . GLN A 1 133 ? 2.51687   39.56405 -17.17397 1.000 32.63946  ? 133 GLN A OE1 1 
ATOM   1118 N NE2 . GLN A 1 133 ? 4.62604   39.10851 -16.49185 1.000 31.52996  ? 133 GLN A NE2 1 
ATOM   1119 N N   . ILE A 1 134 ? 2.50299   33.83719 -14.72952 1.000 27.56628  ? 134 ILE A N   1 
ATOM   1120 C CA  A ILE A 1 134 ? 2.08966   32.45965 -14.99417 0.500 25.47347  ? 134 ILE A CA  1 
ATOM   1121 C CA  B ILE A 1 134 ? 2.07095   32.46604 -15.00154 0.500 30.92865  ? 134 ILE A CA  1 
ATOM   1122 C C   . ILE A 1 134 ? 1.19618   31.96169 -13.86648 1.000 28.91196  ? 134 ILE A C   1 
ATOM   1123 O O   . ILE A 1 134 ? 0.13607   31.36544 -14.09792 1.000 27.89252  ? 134 ILE A O   1 
ATOM   1124 C CB  A ILE A 1 134 ? 3.31379   31.54282 -15.15905 0.500 19.11786  ? 134 ILE A CB  1 
ATOM   1125 C CB  B ILE A 1 134 ? 3.27872   31.53742 -15.23809 0.500 35.82417  ? 134 ILE A CB  1 
ATOM   1126 C CG1 A ILE A 1 134 ? 4.19062   31.96853 -16.34242 0.500 15.76336  ? 134 ILE A CG1 1 
ATOM   1127 C CG1 B ILE A 1 134 ? 2.83142   30.16509 -15.74467 0.500 35.07102  ? 134 ILE A CG1 1 
ATOM   1128 C CG2 A ILE A 1 134 ? 2.85712   30.07745 -15.26278 0.500 18.61730  ? 134 ILE A CG2 1 
ATOM   1129 C CG2 B ILE A 1 134 ? 4.05723   31.32570 -13.96938 0.500 41.28761  ? 134 ILE A CG2 1 
ATOM   1130 C CD1 A ILE A 1 134 ? 5.45157   31.20351 -16.42790 0.500 16.02250  ? 134 ILE A CD1 1 
ATOM   1131 C CD1 B ILE A 1 134 ? 2.21313   30.16462 -17.10362 0.500 41.90240  ? 134 ILE A CD1 1 
ATOM   1132 N N   . LEU A 1 135 ? 1.61952   32.20117 -12.61694 1.000 28.81927  ? 135 LEU A N   1 
ATOM   1133 C CA  . LEU A 1 135 ? 0.85424   31.72128 -11.46787 1.000 26.99741  ? 135 LEU A CA  1 
ATOM   1134 C C   . LEU A 1 135 ? -0.47880  32.45754 -11.35003 1.000 24.24690  ? 135 LEU A C   1 
ATOM   1135 O O   . LEU A 1 135 ? -1.49339  31.85463 -10.97339 1.000 27.64510  ? 135 LEU A O   1 
ATOM   1136 C CB  . LEU A 1 135 ? 1.68883   31.88573 -10.19631 1.000 24.46221  ? 135 LEU A CB  1 
ATOM   1137 C CG  . LEU A 1 135 ? 2.88149   30.93758 -10.12045 1.000 26.43654  ? 135 LEU A CG  1 
ATOM   1138 C CD1 . LEU A 1 135 ? 3.79847   31.33897 -8.92515  1.000 27.99540  ? 135 LEU A CD1 1 
ATOM   1139 C CD2 . LEU A 1 135 ? 2.44023   29.47532 -9.96501  1.000 26.39926  ? 135 LEU A CD2 1 
ATOM   1140 N N   . ARG A 1 136 ? -0.49413  33.75999 -11.65567 1.000 26.39848  ? 136 ARG A N   1 
ATOM   1141 C CA  . ARG A 1 136 ? -1.75057  34.51266 -11.65893 1.000 25.37405  ? 136 ARG A CA  1 
ATOM   1142 C C   . ARG A 1 136 ? -2.74166  33.93053 -12.66286 1.000 29.15879  ? 136 ARG A C   1 
ATOM   1143 O O   . ARG A 1 136 ? -3.92737  33.73335 -12.34723 1.000 29.03468  ? 136 ARG A O   1 
ATOM   1144 C CB  . ARG A 1 136 ? -1.46447  35.98922 -11.95625 1.000 25.29792  ? 136 ARG A CB  1 
ATOM   1145 C CG  . ARG A 1 136 ? -2.64551  36.92540 -11.70119 1.000 30.94998  ? 136 ARG A CG  1 
ATOM   1146 C CD  . ARG A 1 136 ? -2.17417  38.37573 -11.68186 1.000 35.53189  ? 136 ARG A CD  1 
ATOM   1147 N NE  . ARG A 1 136 ? -3.27114  39.34158 -11.64906 1.000 39.68459  ? 136 ARG A NE  1 
ATOM   1148 C CZ  . ARG A 1 136 ? -3.80544  39.93590 -12.70962 1.000 38.02788  ? 136 ARG A CZ  1 
ATOM   1149 N NH1 . ARG A 1 136 ? -3.41459  39.64279 -13.93955 1.000 38.51131  ? 136 ARG A NH1 1 
ATOM   1150 N NH2 . ARG A 1 136 ? -4.73892  40.87212 -12.52798 1.000 40.84192  ? 136 ARG A NH2 1 
ATOM   1151 N N   . GLY A 1 137 ? -2.27752  33.66507 -13.88756 1.000 28.98540  ? 137 GLY A N   1 
ATOM   1152 C CA  . GLY A 1 137 ? -3.12740  33.00140 -14.87075 1.000 27.45381  ? 137 GLY A CA  1 
ATOM   1153 C C   . GLY A 1 137 ? -3.52960  31.59693 -14.44357 1.000 29.13500  ? 137 GLY A C   1 
ATOM   1154 O O   . GLY A 1 137 ? -4.67487  31.17198 -14.65819 1.000 28.85023  ? 137 GLY A O   1 
ATOM   1155 N N   A LEU A 1 138 ? -2.59071  30.85260 -13.84347 0.360 28.80516  ? 138 LEU A N   1 
ATOM   1156 N N   B LEU A 1 138 ? -2.60527  30.86394 -13.81002 0.640 28.76159  ? 138 LEU A N   1 
ATOM   1157 C CA  A LEU A 1 138 ? -2.89329  29.49938 -13.37911 0.360 28.85056  ? 138 LEU A CA  1 
ATOM   1158 C CA  B LEU A 1 138 ? -2.89748  29.49360 -13.39392 0.640 28.63136  ? 138 LEU A CA  1 
ATOM   1159 C C   A LEU A 1 138 ? -3.94934  29.50302 -12.28364 0.360 28.99869  ? 138 LEU A C   1 
ATOM   1160 C C   B LEU A 1 138 ? -3.89586  29.45251 -12.24086 0.640 29.08818  ? 138 LEU A C   1 
ATOM   1161 O O   A LEU A 1 138 ? -4.85482  28.66072 -12.28223 0.360 30.32019  ? 138 LEU A O   1 
ATOM   1162 O O   B LEU A 1 138 ? -4.71067  28.52667 -12.16125 0.640 28.64915  ? 138 LEU A O   1 
ATOM   1163 C CB  A LEU A 1 138 ? -1.63054  28.80515 -12.86902 0.360 29.03225  ? 138 LEU A CB  1 
ATOM   1164 C CB  B LEU A 1 138 ? -1.60717  28.78280 -12.98891 0.640 28.00526  ? 138 LEU A CB  1 
ATOM   1165 C CG  A LEU A 1 138 ? -1.33950  27.40130 -13.40517 0.360 29.93462  ? 138 LEU A CG  1 
ATOM   1166 C CG  B LEU A 1 138 ? -0.75059  28.16844 -14.09817 0.640 27.18044  ? 138 LEU A CG  1 
ATOM   1167 C CD1 A LEU A 1 138 ? -1.65925  27.27102 -14.89556 0.360 30.27686  ? 138 LEU A CD1 1 
ATOM   1168 C CD1 B LEU A 1 138 ? 0.41623   27.39502 -13.48267 0.640 27.26535  ? 138 LEU A CD1 1 
ATOM   1169 C CD2 A LEU A 1 138 ? 0.08804   26.97089 -13.09728 0.360 28.90006  ? 138 LEU A CD2 1 
ATOM   1170 C CD2 B LEU A 1 138 ? -1.57412  27.28081 -15.02807 0.640 28.51488  ? 138 LEU A CD2 1 
ATOM   1171 N N   . LYS A 1 139 ? -3.83676  30.42021 -11.32228 1.000 27.61036  ? 139 LYS A N   1 
ATOM   1172 C CA  . LYS A 1 139 ? -4.84432  30.47044 -10.26754 1.000 28.47855  ? 139 LYS A CA  1 
ATOM   1173 C C   . LYS A 1 139 ? -6.23106  30.59945 -10.88079 1.000 28.54881  ? 139 LYS A C   1 
ATOM   1174 O O   . LYS A 1 139 ? -7.18554  29.92589 -10.45524 1.000 30.09305  ? 139 LYS A O   1 
ATOM   1175 C CB  . LYS A 1 139 ? -4.56909  31.63036 -9.30521  1.000 29.00625  ? 139 LYS A CB  1 
ATOM   1176 C CG  . LYS A 1 139 ? -5.64539  31.76099 -8.23380  1.000 30.47198  ? 139 LYS A CG  1 
ATOM   1177 C CD  . LYS A 1 139 ? -5.66635  33.14048 -7.57858  1.000 32.35034  ? 139 LYS A CD  1 
ATOM   1178 C CE  . LYS A 1 139 ? -6.59113  33.13742 -6.35602  1.000 35.39734  ? 139 LYS A CE  1 
ATOM   1179 N NZ  . LYS A 1 139 ? -6.78141  34.48542 -5.74296  1.000 36.08295  ? 139 LYS A NZ  1 
ATOM   1180 N N   . TYR A 1 140 ? -6.34820  31.45379 -11.89897 1.000 26.87567  ? 140 TYR A N   1 
ATOM   1181 C CA  . TYR A 1 140 ? -7.61065  31.63547 -12.60994 1.000 26.66036  ? 140 TYR A CA  1 
ATOM   1182 C C   . TYR A 1 140 ? -8.03447  30.34863 -13.31193 1.000 23.66362  ? 140 TYR A C   1 
ATOM   1183 O O   . TYR A 1 140 ? -9.18324  29.90552 -13.16834 1.000 27.63335  ? 140 TYR A O   1 
ATOM   1184 C CB  . TYR A 1 140 ? -7.46153  32.79410 -13.61526 1.000 27.33741  ? 140 TYR A CB  1 
ATOM   1185 C CG  . TYR A 1 140 ? -8.64768  32.99309 -14.52730 1.000 26.89646  ? 140 TYR A CG  1 
ATOM   1186 C CD1 . TYR A 1 140 ? -9.71870  33.79069 -14.14913 1.000 24.53443  ? 140 TYR A CD1 1 
ATOM   1187 C CD2 . TYR A 1 140 ? -8.69422  32.38593 -15.78583 1.000 27.59823  ? 140 TYR A CD2 1 
ATOM   1188 C CE1 . TYR A 1 140 ? -10.80562 33.97889 -14.99859 1.000 26.59402  ? 140 TYR A CE1 1 
ATOM   1189 C CE2 . TYR A 1 140 ? -9.79113  32.55651 -16.63155 1.000 31.26183  ? 140 TYR A CE2 1 
ATOM   1190 C CZ  . TYR A 1 140 ? -10.84065 33.34926 -16.22691 1.000 28.20641  ? 140 TYR A CZ  1 
ATOM   1191 O OH  . TYR A 1 140 ? -11.95125 33.55496 -17.03139 1.000 28.67566  ? 140 TYR A OH  1 
ATOM   1192 N N   . ILE A 1 141 ? -7.13464  29.74624 -14.09808 1.000 27.09360  ? 141 ILE A N   1 
ATOM   1193 C CA  . ILE A 1 141 ? -7.48126  28.53246 -14.84289 1.000 32.05700  ? 141 ILE A CA  1 
ATOM   1194 C C   . ILE A 1 141 ? -7.91663  27.42335 -13.88241 1.000 31.49047  ? 141 ILE A C   1 
ATOM   1195 O O   . ILE A 1 141 ? -8.95211  26.76475 -14.08262 1.000 30.45938  ? 141 ILE A O   1 
ATOM   1196 C CB  . ILE A 1 141 ? -6.28770  28.10089 -15.72199 1.000 36.19182  ? 141 ILE A CB  1 
ATOM   1197 C CG1 . ILE A 1 141 ? -6.21859  28.97000 -16.98062 1.000 39.32076  ? 141 ILE A CG1 1 
ATOM   1198 C CG2 . ILE A 1 141 ? -6.36733  26.63922 -16.12394 1.000 41.16084  ? 141 ILE A CG2 1 
ATOM   1199 C CD1 . ILE A 1 141 ? -4.78752  29.26052 -17.42144 1.000 46.29846  ? 141 ILE A CD1 1 
ATOM   1200 N N   . HIS A 1 142 ? -7.14740  27.22257 -12.80837 1.000 28.39252  ? 142 HIS A N   1 
ATOM   1201 C CA  . HIS A 1 142 ? -7.42643  26.13065 -11.87021 1.000 29.63658  ? 142 HIS A CA  1 
ATOM   1202 C C   . HIS A 1 142 ? -8.72354  26.34743 -11.08541 1.000 29.78927  ? 142 HIS A C   1 
ATOM   1203 O O   . HIS A 1 142 ? -9.37488  25.37542 -10.67620 1.000 31.57759  ? 142 HIS A O   1 
ATOM   1204 C CB  . HIS A 1 142 ? -6.23475  25.95776 -10.92561 1.000 24.13589  ? 142 HIS A CB  1 
ATOM   1205 C CG  . HIS A 1 142 ? -5.04360  25.37442 -11.59858 1.000 23.67029  ? 142 HIS A CG  1 
ATOM   1206 N ND1 . HIS A 1 142 ? -3.81874  25.26282 -10.97721 1.000 27.90249  ? 142 HIS A ND1 1 
ATOM   1207 C CD2 . HIS A 1 142 ? -4.88638  24.85535 -12.84595 1.000 26.37076  ? 142 HIS A CD2 1 
ATOM   1208 C CE1 . HIS A 1 142 ? -2.95382  24.71684 -11.81532 1.000 28.44280  ? 142 HIS A CE1 1 
ATOM   1209 N NE2 . HIS A 1 142 ? -3.57278  24.46150 -12.95629 1.000 29.62518  ? 142 HIS A NE2 1 
ATOM   1210 N N   . SER A 1 143 ? -9.10195  27.59902 -10.84190 1.000 30.97767  ? 143 SER A N   1 
ATOM   1211 C CA  . SER A 1 143 ? -10.34557 27.88203 -10.13426 1.000 30.48843  ? 143 SER A CA  1 
ATOM   1212 C C   . SER A 1 143 ? -11.56932 27.46352 -10.93439 1.000 38.16740  ? 143 SER A C   1 
ATOM   1213 O O   . SER A 1 143 ? -12.66098 27.35076 -10.36263 1.000 39.21722  ? 143 SER A O   1 
ATOM   1214 C CB  . SER A 1 143 ? -10.41138 29.37249 -9.78608  1.000 33.54996  ? 143 SER A CB  1 
ATOM   1215 O OG  . SER A 1 143 ? -10.70660 30.14725 -10.93738 1.000 31.96881  ? 143 SER A OG  1 
ATOM   1216 N N   . ALA A 1 144 ? -11.42060 27.23232 -12.23719 1.000 35.07645  ? 144 ALA A N   1 
ATOM   1217 C CA  . ALA A 1 144 ? -12.50083 26.69986 -13.05248 1.000 36.98531  ? 144 ALA A CA  1 
ATOM   1218 C C   . ALA A 1 144 ? -12.37935 25.19112 -13.23606 1.000 35.28365  ? 144 ALA A C   1 
ATOM   1219 O O   . ALA A 1 144 ? -13.08152 24.62192 -14.07459 1.000 36.34842  ? 144 ALA A O   1 
ATOM   1220 C CB  . ALA A 1 144 ? -12.52432 27.40317 -14.41285 1.000 38.08108  ? 144 ALA A CB  1 
ATOM   1221 N N   . ASP A 1 145 ? -11.48405 24.53517 -12.48400 1.000 34.32149  ? 145 ASP A N   1 
ATOM   1222 C CA  . ASP A 1 145 ? -11.17356 23.11271 -12.68594 1.000 39.35037  ? 145 ASP A CA  1 
ATOM   1223 C C   . ASP A 1 145 ? -10.71398 22.82191 -14.11591 1.000 37.24014  ? 145 ASP A C   1 
ATOM   1224 O O   . ASP A 1 145 ? -11.02817 21.77425 -14.68263 1.000 36.55927  ? 145 ASP A O   1 
ATOM   1225 C CB  . ASP A 1 145 ? -12.35436 22.20507 -12.31451 1.000 45.10291  ? 145 ASP A CB  1 
ATOM   1226 C CG  . ASP A 1 145 ? -12.54907 22.08382 -10.81697 1.000 65.48591  ? 145 ASP A CG  1 
ATOM   1227 O OD1 . ASP A 1 145 ? -13.70016 21.85439 -10.37181 1.000 75.49509  ? 145 ASP A OD1 1 
ATOM   1228 O OD2 . ASP A 1 145 ? -11.54612 22.20643 -10.07853 1.000 71.92090  ? 145 ASP A OD2 1 
ATOM   1229 N N   . ILE A 1 146 ? -9.94613  23.73648 -14.69986 1.000 33.88550  ? 146 ILE A N   1 
ATOM   1230 C CA  . ILE A 1 146 ? -9.29399  23.50526 -15.98289 1.000 36.02490  ? 146 ILE A CA  1 
ATOM   1231 C C   . ILE A 1 146 ? -7.82054  23.24540 -15.71661 1.000 36.03661  ? 146 ILE A C   1 
ATOM   1232 O O   . ILE A 1 146 ? -7.17916  23.99566 -14.96867 1.000 37.95382  ? 146 ILE A O   1 
ATOM   1233 C CB  . ILE A 1 146 ? -9.46472  24.70365 -16.93167 1.000 36.62230  ? 146 ILE A CB  1 
ATOM   1234 C CG1 . ILE A 1 146 ? -10.94239 24.91523 -17.29889 1.000 38.16103  ? 146 ILE A CG1 1 
ATOM   1235 C CG2 . ILE A 1 146 ? -8.61928  24.50491 -18.16953 1.000 41.53427  ? 146 ILE A CG2 1 
ATOM   1236 C CD1 . ILE A 1 146 ? -11.23252 26.31915 -17.82843 1.000 39.18881  ? 146 ILE A CD1 1 
ATOM   1237 N N   . ILE A 1 147 ? -7.28913  22.17451 -16.29404 1.000 32.70128  ? 147 ILE A N   1 
ATOM   1238 C CA  . ILE A 1 147 ? -5.86520  21.86375 -16.23489 1.000 31.14948  ? 147 ILE A CA  1 
ATOM   1239 C C   . ILE A 1 147 ? -5.27422  22.15878 -17.60139 1.000 32.24780  ? 147 ILE A C   1 
ATOM   1240 O O   . ILE A 1 147 ? -5.78348  21.66966 -18.61546 1.000 35.23480  ? 147 ILE A O   1 
ATOM   1241 C CB  . ILE A 1 147 ? -5.61742  20.39593 -15.85038 1.000 33.83887  ? 147 ILE A CB  1 
ATOM   1242 C CG1 . ILE A 1 147 ? -6.44062  20.04787 -14.61419 1.000 34.79668  ? 147 ILE A CG1 1 
ATOM   1243 C CG2 . ILE A 1 147 ? -4.12862  20.14289 -15.63908 1.000 36.91177  ? 147 ILE A CG2 1 
ATOM   1244 C CD1 . ILE A 1 147 ? -6.32064  18.60012 -14.17026 1.000 38.70105  ? 147 ILE A CD1 1 
ATOM   1245 N N   . HIS A 1 148 ? -4.17771  22.91969 -17.63774 1.000 31.43279  ? 148 HIS A N   1 
ATOM   1246 C CA  . HIS A 1 148 ? -3.56344  23.19309 -18.92957 1.000 29.49262  ? 148 HIS A CA  1 
ATOM   1247 C C   . HIS A 1 148 ? -2.98866  21.92734 -19.54077 1.000 32.27673  ? 148 HIS A C   1 
ATOM   1248 O O   . HIS A 1 148 ? -3.28163  21.61057 -20.70284 1.000 29.36797  ? 148 HIS A O   1 
ATOM   1249 C CB  . HIS A 1 148 ? -2.47019  24.24884 -18.81250 1.000 30.56487  ? 148 HIS A CB  1 
ATOM   1250 C CG  . HIS A 1 148 ? -1.96156  24.73093 -20.13666 1.000 29.96762  ? 148 HIS A CG  1 
ATOM   1251 N ND1 . HIS A 1 148 ? -1.09147  23.99471 -20.91654 1.000 30.47113  ? 148 HIS A ND1 1 
ATOM   1252 C CD2 . HIS A 1 148 ? -2.21690  25.86603 -20.82790 1.000 30.31168  ? 148 HIS A CD2 1 
ATOM   1253 C CE1 . HIS A 1 148 ? -0.81850  24.66559 -22.02202 1.000 34.06008  ? 148 HIS A CE1 1 
ATOM   1254 N NE2 . HIS A 1 148 ? -1.49540  25.80117 -21.99688 1.000 33.64530  ? 148 HIS A NE2 1 
ATOM   1255 N N   . ARG A 1 149 ? -2.12217  21.23404 -18.78967 1.000 31.56941  ? 149 ARG A N   1 
ATOM   1256 C CA  . ARG A 1 149 ? -1.56857  19.93438 -19.15735 1.000 33.03459  ? 149 ARG A CA  1 
ATOM   1257 C C   . ARG A 1 149 ? -0.32093  20.02582 -20.03162 1.000 32.96205  ? 149 ARG A C   1 
ATOM   1258 O O   . ARG A 1 149 ? 0.37221   19.02439 -20.21273 1.000 39.06568  ? 149 ARG A O   1 
ATOM   1259 C CB  . ARG A 1 149 ? -2.61625  19.09158 -19.89318 1.000 36.24144  ? 149 ARG A CB  1 
ATOM   1260 C CG  . ARG A 1 149 ? -3.76498  18.63603 -19.04056 1.000 48.48755  ? 149 ARG A CG  1 
ATOM   1261 C CD  . ARG A 1 149 ? -4.60918  17.60041 -19.77170 1.000 55.43297  ? 149 ARG A CD  1 
ATOM   1262 N NE  . ARG A 1 149 ? -5.73155  17.19316 -18.94062 1.000 58.62303  ? 149 ARG A NE  1 
ATOM   1263 C CZ  . ARG A 1 149 ? -6.83420  17.91248 -18.78417 1.000 66.29079  ? 149 ARG A CZ  1 
ATOM   1264 N NH1 . ARG A 1 149 ? -7.01204  19.05655 -19.42916 1.000 70.47150  ? 149 ARG A NH1 1 
ATOM   1265 N NH2 . ARG A 1 149 ? -7.77985  17.47700 -17.95717 1.000 68.13991  ? 149 ARG A NH2 1 
ATOM   1266 N N   . ASP A 1 150 ? -0.02963  21.18626 -20.61844 1.000 31.84874  ? 150 ASP A N   1 
ATOM   1267 C CA  . ASP A 1 150 ? 1.03560   21.24338 -21.61564 1.000 32.79775  ? 150 ASP A CA  1 
ATOM   1268 C C   . ASP A 1 150 ? 1.81126   22.54878 -21.50683 1.000 30.42073  ? 150 ASP A C   1 
ATOM   1269 O O   . ASP A 1 150 ? 2.19632   23.15501 -22.51244 1.000 33.52712  ? 150 ASP A O   1 
ATOM   1270 C CB  . ASP A 1 150 ? 0.46158   21.06143 -23.02509 1.000 40.42760  ? 150 ASP A CB  1 
ATOM   1271 C CG  . ASP A 1 150 ? 1.52738   20.79363 -24.07261 1.000 47.41407  ? 150 ASP A CG  1 
ATOM   1272 O OD1 . ASP A 1 150 ? 2.53811   20.14223 -23.74138 1.000 49.84199  ? 150 ASP A OD1 1 
ATOM   1273 O OD2 . ASP A 1 150 ? 1.34721   21.22989 -25.23447 1.000 47.59551  ? 150 ASP A OD2 1 
ATOM   1274 N N   A LEU A 1 151 ? 2.03125   23.00725 -20.28311 0.500 28.21724  ? 151 LEU A N   1 
ATOM   1275 N N   B LEU A 1 151 ? 2.06724   22.99529 -20.28554 0.500 27.83611  ? 151 LEU A N   1 
ATOM   1276 C CA  A LEU A 1 151 ? 2.73886   24.25807 -20.08053 0.500 29.25875  ? 151 LEU A CA  1 
ATOM   1277 C CA  B LEU A 1 151 ? 2.76551   24.25430 -20.09818 0.500 28.96891  ? 151 LEU A CA  1 
ATOM   1278 C C   A LEU A 1 151 ? 4.21876   24.08476 -20.38212 0.500 27.58152  ? 151 LEU A C   1 
ATOM   1279 C C   B LEU A 1 151 ? 4.23702   24.07008 -20.44488 0.500 27.76224  ? 151 LEU A C   1 
ATOM   1280 O O   A LEU A 1 151 ? 4.87283   23.18367 -19.85506 0.500 27.62940  ? 151 LEU A O   1 
ATOM   1281 O O   B LEU A 1 151 ? 4.89829   23.17009 -19.92518 0.500 27.52622  ? 151 LEU A O   1 
ATOM   1282 C CB  A LEU A 1 151 ? 2.53994   24.75208 -18.65193 0.500 30.07675  ? 151 LEU A CB  1 
ATOM   1283 C CB  B LEU A 1 151 ? 2.61117   24.72452 -18.65530 0.500 29.70350  ? 151 LEU A CB  1 
ATOM   1284 C CG  A LEU A 1 151 ? 2.61497   26.26142 -18.46780 0.500 31.48910  ? 151 LEU A CG  1 
ATOM   1285 C CG  B LEU A 1 151 ? 1.37847   25.51404 -18.20978 0.500 28.87521  ? 151 LEU A CG  1 
ATOM   1286 C CD1 A LEU A 1 151 ? 1.57195   26.97326 -19.33086 0.500 34.84241  ? 151 LEU A CD1 1 
ATOM   1287 C CD1 B LEU A 1 151 ? 1.50655   25.80573 -16.71009 0.500 24.32762  ? 151 LEU A CD1 1 
ATOM   1288 C CD2 A LEU A 1 151 ? 2.46539   26.63192 -17.00099 0.500 31.44956  ? 151 LEU A CD2 1 
ATOM   1289 C CD2 B LEU A 1 151 ? 1.12921   26.78607 -19.02397 0.500 29.03247  ? 151 LEU A CD2 1 
ATOM   1290 N N   A LYS A 1 152 ? 4.73318   24.94309 -21.25171 0.500 28.52062  ? 152 LYS A N   1 
ATOM   1291 N N   B LYS A 1 152 ? 4.73489   24.90044 -21.35282 0.500 28.67837  ? 152 LYS A N   1 
ATOM   1292 C CA  A LYS A 1 152 ? 6.14741   24.98264 -21.59109 0.500 27.82918  ? 152 LYS A CA  1 
ATOM   1293 C CA  B LYS A 1 152 ? 6.13729   24.92858 -21.74001 0.500 28.70694  ? 152 LYS A CA  1 
ATOM   1294 C C   A LYS A 1 152 ? 6.44241   26.37343 -22.12012 0.500 27.28149  ? 152 LYS A C   1 
ATOM   1295 C C   B LYS A 1 152 ? 6.43549   26.32135 -22.26121 0.500 28.07263  ? 152 LYS A C   1 
ATOM   1296 O O   A LYS A 1 152 ? 5.52009   27.17332 -22.31352 0.500 28.74011  ? 152 LYS A O   1 
ATOM   1297 O O   B LYS A 1 152 ? 5.50805   27.07418 -22.57726 0.500 31.49236  ? 152 LYS A O   1 
ATOM   1298 C CB  A LYS A 1 152 ? 6.50029   23.90837 -22.62863 0.500 32.25697  ? 152 LYS A CB  1 
ATOM   1299 C CB  B LYS A 1 152 ? 6.46015   23.86819 -22.80312 0.500 34.39398  ? 152 LYS A CB  1 
ATOM   1300 C CG  A LYS A 1 152 ? 5.68458   24.04230 -23.88434 0.500 33.52688  ? 152 LYS A CG  1 
ATOM   1301 C CG  B LYS A 1 152 ? 5.27194   23.46166 -23.65127 0.500 37.48163  ? 152 LYS A CG  1 
ATOM   1302 C CD  A LYS A 1 152 ? 6.12516   23.08491 -24.96279 0.500 36.05474  ? 152 LYS A CD  1 
ATOM   1303 C CD  B LYS A 1 152 ? 5.42392   22.05692 -24.25050 0.500 33.99472  ? 152 LYS A CD  1 
ATOM   1304 C CE  A LYS A 1 152 ? 4.96304   22.74591 -25.84591 0.500 31.93962  ? 152 LYS A CE  1 
ATOM   1305 C CE  B LYS A 1 152 ? 6.03578   22.09386 -25.64311 0.500 35.35475  ? 152 LYS A CE  1 
ATOM   1306 N NZ  A LYS A 1 152 ? 3.99136   21.92415 -25.11522 0.500 32.72328  ? 152 LYS A NZ  1 
ATOM   1307 N NZ  B LYS A 1 152 ? 5.10704   21.59854 -26.72681 0.500 36.03881  ? 152 LYS A NZ  1 
ATOM   1308 N N   . PRO A 1 153 ? 7.71506   26.70704 -22.34761 1.000 28.28743  ? 153 PRO A N   1 
ATOM   1309 C CA  . PRO A 1 153 ? 8.02116   28.08492 -22.77660 1.000 28.59815  ? 153 PRO A CA  1 
ATOM   1310 C C   . PRO A 1 153 ? 7.37410   28.47581 -24.08783 1.000 28.32778  ? 153 PRO A C   1 
ATOM   1311 O O   . PRO A 1 153 ? 7.04396   29.65872 -24.26140 1.000 31.18294  ? 153 PRO A O   1 
ATOM   1312 C CB  . PRO A 1 153 ? 9.54951   28.09947 -22.87384 1.000 29.97831  ? 153 PRO A CB  1 
ATOM   1313 C CG  . PRO A 1 153 ? 9.97863   27.09840 -21.85220 1.000 28.14047  ? 153 PRO A CG  1 
ATOM   1314 C CD  . PRO A 1 153 ? 8.91702   25.98373 -21.90980 1.000 28.67469  ? 153 PRO A CD  1 
ATOM   1315 N N   . SER A 1 154 ? 7.18285   27.53829 -25.01994 1.000 29.43483  ? 154 SER A N   1 
ATOM   1316 C CA  . SER A 1 154 ? 6.59947   27.90885 -26.30648 1.000 32.51618  ? 154 SER A CA  1 
ATOM   1317 C C   . SER A 1 154 ? 5.10981   28.20503 -26.21967 1.000 31.13666  ? 154 SER A C   1 
ATOM   1318 O O   . SER A 1 154 ? 4.54203   28.72622 -27.19260 1.000 35.71089  ? 154 SER A O   1 
ATOM   1319 C CB  . SER A 1 154 ? 6.82357   26.81434 -27.34633 1.000 35.65071  ? 154 SER A CB  1 
ATOM   1320 O OG  . SER A 1 154 ? 6.34198   25.56891 -26.90216 1.000 35.02474  ? 154 SER A OG  1 
ATOM   1321 N N   A ASN A 1 155 ? 4.48277   27.91051 -25.08125 0.820 32.38008  ? 155 ASN A N   1 
ATOM   1322 N N   B ASN A 1 155 ? 4.43737   27.87159 -25.11691 0.180 32.03349  ? 155 ASN A N   1 
ATOM   1323 C CA  A ASN A 1 155 ? 3.07402   28.20214 -24.86424 0.820 34.98228  ? 155 ASN A CA  1 
ATOM   1324 C CA  B ASN A 1 155 ? 3.03697   28.24890 -24.95683 0.180 32.61430  ? 155 ASN A CA  1 
ATOM   1325 C C   A ASN A 1 155 ? 2.86871   29.44998 -24.01875 0.820 32.92063  ? 155 ASN A C   1 
ATOM   1326 C C   B ASN A 1 155 ? 2.85959   29.46315 -24.05257 0.180 31.05521  ? 155 ASN A C   1 
ATOM   1327 O O   A ASN A 1 155 ? 1.76688   29.67500 -23.49597 0.820 30.86991  ? 155 ASN A O   1 
ATOM   1328 O O   B ASN A 1 155 ? 1.76403   29.68033 -23.52259 0.180 30.81080  ? 155 ASN A O   1 
ATOM   1329 C CB  A ASN A 1 155 ? 2.38478   27.00060 -24.22271 0.820 35.54718  ? 155 ASN A CB  1 
ATOM   1330 C CB  B ASN A 1 155 ? 2.19670   27.08098 -24.43128 0.180 33.98317  ? 155 ASN A CB  1 
ATOM   1331 C CG  A ASN A 1 155 ? 2.17511   25.88768 -25.21550 0.820 40.64785  ? 155 ASN A CG  1 
ATOM   1332 C CG  B ASN A 1 155 ? 3.01324   25.84939 -24.13834 0.180 33.08204  ? 155 ASN A CG  1 
ATOM   1333 O OD1 A ASN A 1 155 ? 2.12748   26.12653 -26.42903 0.820 43.36810  ? 155 ASN A OD1 1 
ATOM   1334 O OD1 B ASN A 1 155 ? 3.42746   25.62707 -23.00516 0.180 38.18804  ? 155 ASN A OD1 1 
ATOM   1335 N ND2 A ASN A 1 155 ? 2.02632   24.68252 -24.72271 0.820 37.23502  ? 155 ASN A ND2 1 
ATOM   1336 N ND2 B ASN A 1 155 ? 3.22571   25.02276 -25.15468 0.180 30.13551  ? 155 ASN A ND2 1 
ATOM   1337 N N   . LEU A 1 156 ? 3.90780   30.26095 -23.87565 1.000 30.18347  ? 156 LEU A N   1 
ATOM   1338 C CA  . LEU A 1 156 ? 3.86028   31.48084 -23.07740 1.000 30.90532  ? 156 LEU A CA  1 
ATOM   1339 C C   . LEU A 1 156 ? 4.29436   32.63168 -23.97009 1.000 33.20302  ? 156 LEU A C   1 
ATOM   1340 O O   . LEU A 1 156 ? 5.45330   32.68076 -24.39595 1.000 37.39599  ? 156 LEU A O   1 
ATOM   1341 C CB  . LEU A 1 156 ? 4.75726   31.34181 -21.83980 1.000 29.58851  ? 156 LEU A CB  1 
ATOM   1342 C CG  . LEU A 1 156 ? 4.36561   30.15476 -20.95719 1.000 31.60261  ? 156 LEU A CG  1 
ATOM   1343 C CD1 . LEU A 1 156 ? 5.44686   29.82916 -19.97293 1.000 33.27202  ? 156 LEU A CD1 1 
ATOM   1344 C CD2 . LEU A 1 156 ? 3.03313   30.47233 -20.24431 1.000 31.53739  ? 156 LEU A CD2 1 
ATOM   1345 N N   . ALA A 1 157 ? 3.36757   33.54064 -24.27481 1.000 30.28687  ? 157 ALA A N   1 
ATOM   1346 C CA  . ALA A 1 157 ? 3.67652   34.74280 -25.04199 1.000 36.10511  ? 157 ALA A CA  1 
ATOM   1347 C C   . ALA A 1 157 ? 4.12083   35.85052 -24.10288 1.000 34.83633  ? 157 ALA A C   1 
ATOM   1348 O O   . ALA A 1 157 ? 3.54531   36.03256 -23.02687 1.000 36.27212  ? 157 ALA A O   1 
ATOM   1349 C CB  . ALA A 1 157 ? 2.45808   35.21734 -25.83106 1.000 37.75300  ? 157 ALA A CB  1 
ATOM   1350 N N   . VAL A 1 158 ? 5.13192   36.60680 -24.52404 1.000 38.26512  ? 158 VAL A N   1 
ATOM   1351 C CA  . VAL A 1 158 ? 5.68205   37.69186 -23.71684 1.000 43.19881  ? 158 VAL A CA  1 
ATOM   1352 C C   . VAL A 1 158 ? 5.91383   38.87426 -24.63877 1.000 48.51059  ? 158 VAL A C   1 
ATOM   1353 O O   . VAL A 1 158 ? 6.60950   38.74068 -25.65157 1.000 49.99182  ? 158 VAL A O   1 
ATOM   1354 C CB  . VAL A 1 158 ? 6.99190   37.28567 -23.01824 1.000 43.00130  ? 158 VAL A CB  1 
ATOM   1355 C CG1 . VAL A 1 158 ? 7.48935   38.40213 -22.11053 1.000 47.05952  ? 158 VAL A CG1 1 
ATOM   1356 C CG2 . VAL A 1 158 ? 6.78919   35.98290 -22.20645 1.000 41.80868  ? 158 VAL A CG2 1 
ATOM   1357 N N   . ASN A 1 159 ? 5.32821   40.02578 -24.31025 1.000 50.96391  ? 159 ASN A N   1 
ATOM   1358 C CA  . ASN A 1 159 ? 5.51295   41.18579 -25.16947 1.000 51.31263  ? 159 ASN A CA  1 
ATOM   1359 C C   . ASN A 1 159 ? 6.76640   41.93755 -24.72869 1.000 57.90810  ? 159 ASN A C   1 
ATOM   1360 O O   . ASN A 1 159 ? 7.47805   41.53583 -23.80421 1.000 53.58938  ? 159 ASN A O   1 
ATOM   1361 C CB  . ASN A 1 159 ? 4.26369   42.07489 -25.16992 1.000 49.58786  ? 159 ASN A CB  1 
ATOM   1362 C CG  . ASN A 1 159 ? 4.06109   42.83053 -23.86241 1.000 50.16409  ? 159 ASN A CG  1 
ATOM   1363 O OD1 . ASN A 1 159 ? 4.96109   42.91453 -23.02354 1.000 52.39710  ? 159 ASN A OD1 1 
ATOM   1364 N ND2 . ASN A 1 159 ? 2.85272   43.34072 -23.66393 1.000 52.17062  ? 159 ASN A ND2 1 
ATOM   1365 N N   . GLU A 1 160 ? 7.04642   43.05153 -25.39512 1.000 65.07794  ? 160 GLU A N   1 
ATOM   1366 C CA  . GLU A 1 160 ? 8.28252   43.76271 -25.10977 1.000 69.78790  ? 160 GLU A CA  1 
ATOM   1367 C C   . GLU A 1 160 ? 8.32227   44.30734 -23.68944 1.000 66.15033  ? 160 GLU A C   1 
ATOM   1368 O O   . GLU A 1 160 ? 9.40273   44.64499 -23.19589 1.000 66.39910  ? 160 GLU A O   1 
ATOM   1369 C CB  . GLU A 1 160 ? 8.46620   44.89081 -26.11581 1.000 76.15444  ? 160 GLU A CB  1 
ATOM   1370 C CG  . GLU A 1 160 ? 9.91179   45.18224 -26.41655 1.000 86.33432  ? 160 GLU A CG  1 
ATOM   1371 C CD  . GLU A 1 160 ? 10.08076  46.45233 -27.20656 1.000 92.18187  ? 160 GLU A CD  1 
ATOM   1372 O OE1 . GLU A 1 160 ? 11.09332  47.14681 -26.98662 1.000 94.30641  ? 160 GLU A OE1 1 
ATOM   1373 O OE2 . GLU A 1 160 ? 9.20117   46.75420 -28.04376 1.000 94.14958  ? 160 GLU A OE2 1 
ATOM   1374 N N   . ASP A 1 161 ? 7.17620   44.39623 -23.01985 1.000 62.11072  ? 161 ASP A N   1 
ATOM   1375 C CA  . ASP A 1 161 ? 7.10834   44.89247 -21.65569 1.000 61.63059  ? 161 ASP A CA  1 
ATOM   1376 C C   . ASP A 1 161 ? 7.13445   43.75752 -20.61725 1.000 57.60161  ? 161 ASP A C   1 
ATOM   1377 O O   . ASP A 1 161 ? 6.78716   43.98361 -19.45222 1.000 59.63650  ? 161 ASP A O   1 
ATOM   1378 C CB  . ASP A 1 161 ? 5.85563   45.75828 -21.49019 1.000 63.35263  ? 161 ASP A CB  1 
ATOM   1379 C CG  . ASP A 1 161 ? 5.91982   47.05118 -22.30954 1.000 69.69711  ? 161 ASP A CG  1 
ATOM   1380 O OD1 . ASP A 1 161 ? 7.03695   47.53976 -22.57937 1.000 68.85634  ? 161 ASP A OD1 1 
ATOM   1381 O OD2 . ASP A 1 161 ? 4.84712   47.57925 -22.68933 1.000 71.35981  ? 161 ASP A OD2 1 
ATOM   1382 N N   . CYS A 1 162 ? 7.56156   42.55409 -21.01357 1.000 54.05534  ? 162 CYS A N   1 
ATOM   1383 C CA  . CYS A 1 162 ? 7.53495   41.34522 -20.18101 1.000 49.15504  ? 162 CYS A CA  1 
ATOM   1384 C C   . CYS A 1 162 ? 6.13521   41.00574 -19.67361 1.000 42.93327  ? 162 CYS A C   1 
ATOM   1385 O O   . CYS A 1 162 ? 5.99190   40.26263 -18.69498 1.000 40.04247  ? 162 CYS A O   1 
ATOM   1386 C CB  . CYS A 1 162 ? 8.51174   41.43343 -18.99915 1.000 55.83826  ? 162 CYS A CB  1 
ATOM   1387 S SG  . CYS A 1 162 ? 10.29610  41.32007 -19.42786 1.000 70.37381  ? 162 CYS A SG  1 
ATOM   1388 N N   . GLU A 1 163 ? 5.08708   41.52428 -20.30900 1.000 40.92123  ? 163 GLU A N   1 
ATOM   1389 C CA  . GLU A 1 163 ? 3.74126   41.04801 -20.02126 1.000 38.85486  ? 163 GLU A CA  1 
ATOM   1390 C C   . GLU A 1 163 ? 3.52572   39.69906 -20.69126 1.000 36.87141  ? 163 GLU A C   1 
ATOM   1391 O O   . GLU A 1 163 ? 3.95130   39.48976 -21.83039 1.000 41.33357  ? 163 GLU A O   1 
ATOM   1392 C CB  . GLU A 1 163 ? 2.70054   42.05448 -20.49830 1.000 43.74674  ? 163 GLU A CB  1 
ATOM   1393 C CG  . GLU A 1 163 ? 2.63575   43.29684 -19.62269 1.000 47.48070  ? 163 GLU A CG  1 
ATOM   1394 C CD  . GLU A 1 163 ? 2.14950   44.51855 -20.35989 1.000 53.76387  ? 163 GLU A CD  1 
ATOM   1395 O OE1 . GLU A 1 163 ? 1.85976   44.41804 -21.56978 1.000 54.42549  ? 163 GLU A OE1 1 
ATOM   1396 O OE2 . GLU A 1 163 ? 2.04314   45.58106 -19.71567 1.000 60.43721  ? 163 GLU A OE2 1 
ATOM   1397 N N   . LEU A 1 164 ? 2.85777   38.78459 -19.97911 1.000 34.13962  ? 164 LEU A N   1 
ATOM   1398 C CA  . LEU A 1 164 ? 2.80804   37.37513 -20.35770 1.000 30.35706  ? 164 LEU A CA  1 
ATOM   1399 C C   . LEU A 1 164 ? 1.37226   36.87166 -20.44252 1.000 34.23920  ? 164 LEU A C   1 
ATOM   1400 O O   . LEU A 1 164 ? 0.50285   37.28210 -19.65995 1.000 33.96392  ? 164 LEU A O   1 
ATOM   1401 C CB  . LEU A 1 164 ? 3.59655   36.52729 -19.34834 1.000 30.51158  ? 164 LEU A CB  1 
ATOM   1402 C CG  . LEU A 1 164 ? 3.60812   35.00567 -19.48581 1.000 28.89241  ? 164 LEU A CG  1 
ATOM   1403 C CD1 . LEU A 1 164 ? 4.91683   34.47371 -18.93630 1.000 29.90298  ? 164 LEU A CD1 1 
ATOM   1404 C CD2 . LEU A 1 164 ? 2.40490   34.34711 -18.77274 1.000 27.58095  ? 164 LEU A CD2 1 
ATOM   1405 N N   . LYS A 1 165 ? 1.13901   35.95186 -21.39212 1.000 31.46039  ? 165 LYS A N   1 
ATOM   1406 C CA  . LYS A 1 165 ? -0.15181  35.29288 -21.56133 1.000 31.14476  ? 165 LYS A CA  1 
ATOM   1407 C C   . LYS A 1 165 ? 0.05333   33.79875 -21.79521 1.000 31.43004  ? 165 LYS A C   1 
ATOM   1408 O O   . LYS A 1 165 ? 0.93884   33.40212 -22.56094 1.000 33.53838  ? 165 LYS A O   1 
ATOM   1409 C CB  . LYS A 1 165 ? -0.92544  35.88955 -22.74375 1.000 36.14313  ? 165 LYS A CB  1 
ATOM   1410 C CG  . LYS A 1 165 ? -1.76377  37.09536 -22.41387 1.000 38.74745  ? 165 LYS A CG  1 
ATOM   1411 C CD  . LYS A 1 165 ? -2.90012  37.24213 -23.42412 1.000 43.09889  ? 165 LYS A CD  1 
ATOM   1412 C CE  . LYS A 1 165 ? -2.96599  38.65423 -23.96632 1.000 48.42713  ? 165 LYS A CE  1 
ATOM   1413 N NZ  . LYS A 1 165 ? -3.54310  39.55443 -22.93583 1.000 49.73222  ? 165 LYS A NZ  1 
ATOM   1414 N N   . ILE A 1 166 ? -0.78603  32.98144 -21.15839 1.000 27.38284  ? 166 ILE A N   1 
ATOM   1415 C CA  . ILE A 1 166 ? -0.75333  31.52941 -21.34572 1.000 26.11273  ? 166 ILE A CA  1 
ATOM   1416 C C   . ILE A 1 166 ? -1.54853  31.17277 -22.59551 1.000 28.00149  ? 166 ILE A C   1 
ATOM   1417 O O   . ILE A 1 166 ? -2.68087  31.63751 -22.76106 1.000 32.64017  ? 166 ILE A O   1 
ATOM   1418 C CB  . ILE A 1 166 ? -1.32894  30.81866 -20.11188 1.000 25.06379  ? 166 ILE A CB  1 
ATOM   1419 C CG1 . ILE A 1 166 ? -0.48787  31.12765 -18.86027 1.000 25.52969  ? 166 ILE A CG1 1 
ATOM   1420 C CG2 . ILE A 1 166 ? -1.43752  29.33905 -20.34942 1.000 29.48116  ? 166 ILE A CG2 1 
ATOM   1421 C CD1 . ILE A 1 166 ? -1.15336  30.64861 -17.54518 1.000 27.54686  ? 166 ILE A CD1 1 
ATOM   1422 N N   . LEU A 1 167 ? -0.96912  30.32991 -23.46848 1.000 28.62949  ? 167 LEU A N   1 
ATOM   1423 C CA  . LEU A 1 167 ? -1.50228  30.00171 -24.78701 1.000 32.14601  ? 167 LEU A CA  1 
ATOM   1424 C C   . LEU A 1 167 ? -1.76676  28.50178 -24.89790 1.000 37.86087  ? 167 LEU A C   1 
ATOM   1425 O O   . LEU A 1 167 ? -1.30584  27.70631 -24.07608 1.000 38.75048  ? 167 LEU A O   1 
ATOM   1426 C CB  . LEU A 1 167 ? -0.50364  30.37239 -25.89906 1.000 36.72884  ? 167 LEU A CB  1 
ATOM   1427 C CG  . LEU A 1 167 ? 0.13484   31.75602 -25.89840 1.000 43.26263  ? 167 LEU A CG  1 
ATOM   1428 C CD1 . LEU A 1 167 ? 1.02003   31.91606 -27.13023 1.000 49.92687  ? 167 LEU A CD1 1 
ATOM   1429 C CD2 . LEU A 1 167 ? -0.91433  32.82181 -25.87224 1.000 46.14829  ? 167 LEU A CD2 1 
ATOM   1430 N N   A ASP A 1 168 ? -2.45559  28.10207 -25.97564 0.660 38.86470  ? 168 ASP A N   1 
ATOM   1431 N N   B ASP A 1 168 ? -2.55463  28.15861 -25.92452 0.340 38.61938  ? 168 ASP A N   1 
ATOM   1432 C CA  A ASP A 1 168 ? -2.49648  26.71376 -26.45151 0.660 39.93920  ? 168 ASP A CA  1 
ATOM   1433 C CA  B ASP A 1 168 ? -2.87733  26.79160 -26.31610 0.340 39.87571  ? 168 ASP A CA  1 
ATOM   1434 C C   A ASP A 1 168 ? -2.63211  25.66034 -25.35468 0.660 38.37226  ? 168 ASP A C   1 
ATOM   1435 C C   B ASP A 1 168 ? -3.94362  26.16566 -25.43417 0.340 40.84983  ? 168 ASP A C   1 
ATOM   1436 O O   A ASP A 1 168 ? -1.68586  24.91200 -25.07248 0.660 37.12960  ? 168 ASP A O   1 
ATOM   1437 O O   B ASP A 1 168 ? -5.14451  26.34139 -25.67562 0.340 41.55797  ? 168 ASP A O   1 
ATOM   1438 C CB  A ASP A 1 168 ? -1.24513  26.39445 -27.27365 0.660 45.49970  ? 168 ASP A CB  1 
ATOM   1439 C CB  B ASP A 1 168 ? -1.63033  25.91245 -26.29396 0.340 42.79539  ? 168 ASP A CB  1 
ATOM   1440 C CG  A ASP A 1 168 ? -1.12648  27.25126 -28.52200 0.660 52.02303  ? 168 ASP A CG  1 
ATOM   1441 C CG  B ASP A 1 168 ? -0.76258  26.11024 -27.50646 0.340 45.86846  ? 168 ASP A CG  1 
ATOM   1442 O OD1 A ASP A 1 168 ? -2.16816  27.66842 -29.06263 0.660 49.07573  ? 168 ASP A OD1 1 
ATOM   1443 O OD1 B ASP A 1 168 ? -1.08442  26.99353 -28.33233 0.340 47.59847  ? 168 ASP A OD1 1 
ATOM   1444 O OD2 A ASP A 1 168 ? 0.01265   27.47555 -28.98520 0.660 58.25716  ? 168 ASP A OD2 1 
ATOM   1445 O OD2 B ASP A 1 168 ? 0.23364   25.37292 -27.63993 0.340 48.34324  ? 168 ASP A OD2 1 
ATOM   1446 N N   A PHE A 1 169 ? -3.81642  25.56701 -24.76329 0.660 39.87169  ? 169 PHE A N   1 
ATOM   1447 N N   B PHE A 1 169 ? -3.49010  25.43167 -24.41837 0.340 37.38118  ? 169 PHE A N   1 
ATOM   1448 C CA  A PHE A 1 169 ? -4.08490  24.56793 -23.74094 0.660 42.86752  ? 169 PHE A CA  1 
ATOM   1449 C CA  B PHE A 1 169 ? -4.30681  24.53925 -23.60625 0.340 43.07526  ? 169 PHE A CA  1 
ATOM   1450 C C   A PHE A 1 169 ? -3.91376  23.15601 -24.29293 0.660 44.91454  ? 169 PHE A C   1 
ATOM   1451 C C   B PHE A 1 169 ? -4.24678  23.13195 -24.17901 0.340 47.86729  ? 169 PHE A C   1 
ATOM   1452 O O   A PHE A 1 169 ? -3.94199  22.91954 -25.50716 0.660 41.24387  ? 169 PHE A O   1 
ATOM   1453 O O   B PHE A 1 169 ? -4.63366  22.89211 -25.32954 0.340 46.93081  ? 169 PHE A O   1 
ATOM   1454 C CB  A PHE A 1 169 ? -5.49609  24.75782 -23.19035 0.660 43.19589  ? 169 PHE A CB  1 
ATOM   1455 C CB  B PHE A 1 169 ? -5.74972  25.03186 -23.50222 0.340 41.77364  ? 169 PHE A CB  1 
ATOM   1456 C CG  A PHE A 1 169 ? -5.64018  25.99957 -22.36886 0.660 46.61871  ? 169 PHE A CG  1 
ATOM   1457 C CG  B PHE A 1 169 ? -5.90386  26.21678 -22.59862 0.340 43.59763  ? 169 PHE A CG  1 
ATOM   1458 C CD1 A PHE A 1 169 ? -5.42975  27.24441 -22.93766 0.660 45.43542  ? 169 PHE A CD1 1 
ATOM   1459 C CD1 B PHE A 1 169 ? -6.02596  26.04310 -21.23168 0.340 42.93224  ? 169 PHE A CD1 1 
ATOM   1460 C CD2 A PHE A 1 169 ? -5.94971  25.92146 -21.02742 0.660 44.50696  ? 169 PHE A CD2 1 
ATOM   1461 C CD2 B PHE A 1 169 ? -5.89155  27.50133 -23.11030 0.340 44.71191  ? 169 PHE A CD2 1 
ATOM   1462 C CE1 A PHE A 1 169 ? -5.53044  28.38500 -22.18979 0.660 41.96565  ? 169 PHE A CE1 1 
ATOM   1463 C CE1 B PHE A 1 169 ? -6.15057  27.12417 -20.39333 0.340 43.71863  ? 169 PHE A CE1 1 
ATOM   1464 C CE2 A PHE A 1 169 ? -6.05655  27.05120 -20.27271 0.660 41.52613  ? 169 PHE A CE2 1 
ATOM   1465 C CE2 B PHE A 1 169 ? -6.01470  28.59080 -22.27789 0.340 46.24580  ? 169 PHE A CE2 1 
ATOM   1466 C CZ  A PHE A 1 169 ? -5.85163  28.29479 -20.85254 0.660 43.78930  ? 169 PHE A CZ  1 
ATOM   1467 C CZ  B PHE A 1 169 ? -6.14530  28.40463 -20.91585 0.340 45.86387  ? 169 PHE A CZ  1 
ATOM   1468 N N   . GLY A 1 170 ? -3.73690  22.20858 -23.37400 1.000 48.77800  ? 170 GLY A N   1 
ATOM   1469 C CA  . GLY A 1 170 ? -3.56574  20.82157 -23.74846 1.000 58.44829  ? 170 GLY A CA  1 
ATOM   1470 C C   . GLY A 1 170 ? -4.87241  20.12698 -24.04276 1.000 66.56281  ? 170 GLY A C   1 
ATOM   1471 O O   . GLY A 1 170 ? -5.45962  19.47309 -23.17487 1.000 73.38648  ? 170 GLY A O   1 
ATOM   1472 N N   A LEU A 1 171 ? -5.38881  20.29959 -25.25598 0.500 63.94182  ? 171 LEU A N   1 
ATOM   1473 N N   B LEU A 1 171 ? -5.29477  20.25103 -25.29665 0.500 67.12212  ? 171 LEU A N   1 
ATOM   1474 C CA  A LEU A 1 171 ? -6.72302  19.79851 -25.56649 0.500 64.30022  ? 171 LEU A CA  1 
ATOM   1475 C CA  B LEU A 1 171 ? -6.32356  19.42165 -25.89250 0.500 70.46756  ? 171 LEU A CA  1 
ATOM   1476 C C   A LEU A 1 171 ? -6.75287  18.30382 -25.85381 0.500 67.37203  ? 171 LEU A C   1 
ATOM   1477 C C   B LEU A 1 171 ? -5.85761  18.73596 -27.16617 0.500 78.12911  ? 171 LEU A C   1 
ATOM   1478 O O   A LEU A 1 171 ? -7.76658  17.81361 -26.36591 0.500 62.57272  ? 171 LEU A O   1 
ATOM   1479 O O   B LEU A 1 171 ? -6.45035  17.72220 -27.55200 0.500 78.85469  ? 171 LEU A O   1 
ATOM   1480 C CB  A LEU A 1 171 ? -7.31737  20.57459 -26.74339 0.500 61.55624  ? 171 LEU A CB  1 
ATOM   1481 C CB  B LEU A 1 171 ? -7.56530  20.26692 -26.20135 0.500 65.34334  ? 171 LEU A CB  1 
ATOM   1482 C CG  A LEU A 1 171 ? -6.97112  22.06165 -26.72924 0.500 59.60703  ? 171 LEU A CG  1 
ATOM   1483 C CG  B LEU A 1 171 ? -7.15011  21.69033 -26.57832 0.500 60.30617  ? 171 LEU A CG  1 
ATOM   1484 C CD1 A LEU A 1 171 ? -6.92042  22.62305 -28.13970 0.500 61.72364  ? 171 LEU A CD1 1 
ATOM   1485 C CD1 B LEU A 1 171 ? -7.23808  21.88288 -28.07128 0.500 60.75565  ? 171 LEU A CD1 1 
ATOM   1486 C CD2 A LEU A 1 171 ? -7.96405  22.82087 -25.86608 0.500 57.23020  ? 171 LEU A CD2 1 
ATOM   1487 C CD2 B LEU A 1 171 ? -7.98675  22.71634 -25.83750 0.500 57.31278  ? 171 LEU A CD2 1 
ATOM   1488 N N   A ALA A 1 172 ? -5.67680  17.58603 -25.52086 0.500 72.92298  ? 172 ALA A N   1 
ATOM   1489 N N   B ALA A 1 172 ? -4.80258  19.24823 -27.81190 0.500 84.73404  ? 172 ALA A N   1 
ATOM   1490 C CA  A ALA A 1 172 ? -5.57782  16.14079 -25.68846 0.500 77.53760  ? 172 ALA A CA  1 
ATOM   1491 C CA  B ALA A 1 172 ? -4.30245  18.66041 -29.05083 0.500 89.11608  ? 172 ALA A CA  1 
ATOM   1492 C C   A ALA A 1 172 ? -5.14094  15.75950 -27.08852 0.500 82.62060  ? 172 ALA A C   1 
ATOM   1493 C C   B ALA A 1 172 ? -3.98985  17.17941 -28.89281 0.500 93.40431  ? 172 ALA A C   1 
ATOM   1494 O O   A ALA A 1 172 ? -5.98033  15.48109 -27.95023 0.500 82.22744  ? 172 ALA A O   1 
ATOM   1495 O O   B ALA A 1 172 ? -4.10525  16.41752 -29.85938 0.500 95.57575  ? 172 ALA A O   1 
ATOM   1496 C CB  A ALA A 1 172 ? -6.90056  15.45507 -25.39631 0.500 77.28755  ? 172 ALA A CB  1 
ATOM   1497 C CB  B ALA A 1 172 ? -3.05788  19.41326 -29.52630 0.500 88.08556  ? 172 ALA A CB  1 
ATOM   1498 N N   A ARG A 1 173 ? -3.83415  15.72834 -27.31895 0.500 87.65790  ? 173 ARG A N   1 
ATOM   1499 N N   B ARG A 1 173 ? -3.56987  16.75553 -27.69747 0.500 94.79681  ? 173 ARG A N   1 
ATOM   1500 C CA  A ARG A 1 173 ? -3.31029  15.26912 -28.59530 0.500 91.74898  ? 173 ARG A CA  1 
ATOM   1501 C CA  B ARG A 1 173 ? -3.47582  15.34578 -27.32552 0.500 96.22431  ? 173 ARG A CA  1 
ATOM   1502 C C   A ARG A 1 173 ? -1.94846  14.62487 -28.38260 0.500 94.36201  ? 173 ARG A C   1 
ATOM   1503 C C   B ARG A 1 173 ? -2.21991  14.64591 -27.84439 0.500 96.40516  ? 173 ARG A C   1 
ATOM   1504 O O   A ARG A 1 173 ? -1.86973  13.43919 -28.04315 0.500 95.80393  ? 173 ARG A O   1 
ATOM   1505 O O   B ARG A 1 173 ? -2.19846  13.41367 -27.92367 0.500 96.75264  ? 173 ARG A O   1 
ATOM   1506 C CB  A ARG A 1 173 ? -3.21674  16.42761 -29.59164 0.500 91.83928  ? 173 ARG A CB  1 
ATOM   1507 C CB  B ARG A 1 173 ? -4.74396  14.60631 -27.77506 0.500 96.75725  ? 173 ARG A CB  1 
ATOM   1508 C CG  A ARG A 1 173 ? -4.54939  16.83302 -30.21044 0.500 91.32419  ? 173 ARG A CG  1 
ATOM   1509 C CG  B ARG A 1 173 ? -4.60082  13.75076 -29.01982 0.500 97.37869  ? 173 ARG A CG  1 
ATOM   1510 C CD  A ARG A 1 173 ? -5.11107  18.05026 -29.49833 0.500 90.35092  ? 173 ARG A CD  1 
ATOM   1511 C CD  B ARG A 1 173 ? -5.02227  12.32101 -28.76707 0.500 97.57321  ? 173 ARG A CD  1 
ATOM   1512 N NE  A ARG A 1 173 ? -4.20157  18.50551 -28.45321 0.500 89.96715  ? 173 ARG A NE  1 
ATOM   1513 N NE  B ARG A 1 173 ? -5.51819  11.69619 -29.98723 0.500 97.32150  ? 173 ARG A NE  1 
ATOM   1514 C CZ  A ARG A 1 173 ? -4.00691  19.77457 -28.12155 0.500 86.80587  ? 173 ARG A CZ  1 
ATOM   1515 C CZ  B ARG A 1 173 ? -6.55986  12.13290 -30.68289 0.500 96.43332  ? 173 ARG A CZ  1 
ATOM   1516 N NH1 A ARG A 1 173 ? -4.66166  20.75473 -28.72264 0.500 85.98707  ? 173 ARG A NH1 1 
ATOM   1517 N NH1 B ARG A 1 173 ? -7.24277  13.20407 -30.30931 0.500 96.50020  ? 173 ARG A NH1 1 
ATOM   1518 N NH2 A ARG A 1 173 ? -3.13101  20.06734 -27.16390 0.500 83.26564  ? 173 ARG A NH2 1 
ATOM   1519 N NH2 B ARG A 1 173 ? -6.92863  11.47629 -31.77888 0.500 95.51413  ? 173 ARG A NH2 1 
ATOM   1520 N N   A HIS A 1 174 ? -0.88486  15.42121 -28.53703 0.500 94.72885  ? 174 HIS A N   1 
ATOM   1521 N N   B HIS A 1 174 ? -1.16885  15.40901 -28.17187 0.500 95.61899  ? 174 HIS A N   1 
ATOM   1522 C CA  A HIS A 1 174 ? 0.50574   14.97031 -28.52835 0.500 93.94640  ? 174 HIS A CA  1 
ATOM   1523 C CA  B HIS A 1 174 ? 0.16420   14.93673 -28.56091 0.500 94.18117  ? 174 HIS A CA  1 
ATOM   1524 C C   A HIS A 1 174 ? 0.62736   13.45948 -28.67555 0.500 89.59390  ? 174 HIS A C   1 
ATOM   1525 C C   B HIS A 1 174 ? 0.30647   13.42581 -28.73480 0.500 89.22509  ? 174 HIS A C   1 
ATOM   1526 O O   A HIS A 1 174 ? 0.59893   12.72326 -27.68344 0.500 89.91166  ? 174 HIS A O   1 
ATOM   1527 O O   B HIS A 1 174 ? 0.06217   12.65745 -27.79811 0.500 88.00538  ? 174 HIS A O   1 
ATOM   1528 C CB  A HIS A 1 174 ? 1.23249   15.43608 -27.25942 0.500 97.08594  ? 174 HIS A CB  1 
ATOM   1529 C CB  B HIS A 1 174 ? 1.19373   15.41072 -27.53072 0.500 96.97105  ? 174 HIS A CB  1 
ATOM   1530 C CG  A HIS A 1 174 ? 0.32373   15.86017 -26.14639 0.500 100.09677 ? 174 HIS A CG  1 
ATOM   1531 C CG  B HIS A 1 174 ? 0.63216   15.58216 -26.15339 0.500 99.63895  ? 174 HIS A CG  1 
ATOM   1532 N ND1 A HIS A 1 174 ? -0.67479  15.05210 -25.64585 0.500 100.49596 ? 174 HIS A ND1 1 
ATOM   1533 N ND1 B HIS A 1 174 ? 0.20999   14.51832 -25.38465 0.500 99.74571  ? 174 HIS A ND1 1 
ATOM   1534 C CD2 A HIS A 1 174 ? 0.26998   17.00974 -25.43171 0.500 100.77010 ? 174 HIS A CD2 1 
ATOM   1535 C CD2 B HIS A 1 174 ? 0.41881   16.69265 -25.40806 0.500 100.85801 ? 174 HIS A CD2 1 
ATOM   1536 C CE1 A HIS A 1 174 ? -1.30498  15.68555 -24.67232 0.500 100.21389 ? 174 HIS A CE1 1 
ATOM   1537 C CE1 B HIS A 1 174 ? -0.23851  14.96576 -24.22518 0.500 100.10561 ? 174 HIS A CE1 1 
ATOM   1538 N NE2 A HIS A 1 174 ? -0.75201  16.87596 -24.52325 0.500 100.65539 ? 174 HIS A NE2 1 
ATOM   1539 N NE2 B HIS A 1 174 ? -0.12278  16.28174 -24.21381 0.500 101.12769 ? 174 HIS A NE2 1 
ATOM   1540 N N   . THR A 1 175 ? 0.74674   12.99730 -29.91657 1.000 85.13688  ? 175 THR A N   1 
ATOM   1541 C CA  . THR A 1 175 ? 0.91956   11.57951 -30.19476 1.000 79.09821  ? 175 THR A CA  1 
ATOM   1542 C C   . THR A 1 175 ? 2.15277   11.01820 -29.48129 1.000 75.22663  ? 175 THR A C   1 
ATOM   1543 O O   . THR A 1 175 ? 3.07162   11.74432 -29.08942 1.000 72.79162  ? 175 THR A O   1 
ATOM   1544 C CB  . THR A 1 175 ? 1.02760   11.35062 -31.70475 1.000 76.44203  ? 175 THR A CB  1 
ATOM   1545 O OG1 . THR A 1 175 ? 2.35237   11.66889 -32.14856 1.000 73.37730  ? 175 THR A OG1 1 
ATOM   1546 C CG2 . THR A 1 175 ? 0.02069   12.21957 -32.45541 1.000 76.13392  ? 175 THR A CG2 1 
ATOM   1547 N N   . ASP A 1 176 ? 2.16224   9.69250  -29.31713 1.000 72.44824  ? 176 ASP A N   1 
ATOM   1548 C CA  . ASP A 1 176 ? 3.27163   9.04655  -28.62336 1.000 68.12590  ? 176 ASP A CA  1 
ATOM   1549 C C   . ASP A 1 176 ? 4.59337   9.32341  -29.31979 1.000 63.99200  ? 176 ASP A C   1 
ATOM   1550 O O   . ASP A 1 176 ? 5.63273   9.44540  -28.66060 1.000 60.14676  ? 176 ASP A O   1 
ATOM   1551 C CB  . ASP A 1 176 ? 3.03596   7.53925  -28.53314 1.000 72.53527  ? 176 ASP A CB  1 
ATOM   1552 C CG  . ASP A 1 176 ? 2.09709   7.16417  -27.40245 1.000 75.17385  ? 176 ASP A CG  1 
ATOM   1553 O OD1 . ASP A 1 176 ? 2.02669   7.92109  -26.40791 1.000 75.14940  ? 176 ASP A OD1 1 
ATOM   1554 O OD2 . ASP A 1 176 ? 1.43866   6.10652  -27.50825 1.000 74.17984  ? 176 ASP A OD2 1 
ATOM   1555 N N   . ASP A 1 177 ? 4.57647   9.42742  -30.64896 1.000 59.92561  ? 177 ASP A N   1 
ATOM   1556 C CA  . ASP A 1 177 ? 5.81665   9.65685  -31.37775 1.000 63.07478  ? 177 ASP A CA  1 
ATOM   1557 C C   . ASP A 1 177 ? 6.33652   11.07629 -31.15184 1.000 63.96834  ? 177 ASP A C   1 
ATOM   1558 O O   . ASP A 1 177 ? 7.55368   11.29377 -31.10998 1.000 64.40214  ? 177 ASP A O   1 
ATOM   1559 C CB  . ASP A 1 177 ? 5.59640   9.37491  -32.86530 1.000 65.63998  ? 177 ASP A CB  1 
ATOM   1560 C CG  . ASP A 1 177 ? 6.83797   9.61514  -33.69424 1.000 71.76633  ? 177 ASP A CG  1 
ATOM   1561 O OD1 . ASP A 1 177 ? 7.77705   8.79564  -33.60502 1.000 71.74652  ? 177 ASP A OD1 1 
ATOM   1562 O OD2 . ASP A 1 177 ? 6.88137   10.61779 -34.43276 1.000 75.46007  ? 177 ASP A OD2 1 
ATOM   1563 N N   . GLU A 1 178 ? 5.43470   12.04699 -30.98111 1.000 60.05371  ? 178 GLU A N   1 
ATOM   1564 C CA  . GLU A 1 178 ? 5.84824   13.41521 -30.68877 1.000 60.37533  ? 178 GLU A CA  1 
ATOM   1565 C C   . GLU A 1 178 ? 6.47561   13.54175 -29.30375 1.000 56.21880  ? 178 GLU A C   1 
ATOM   1566 O O   . GLU A 1 178 ? 7.16053   14.53418 -29.02706 1.000 57.24452  ? 178 GLU A O   1 
ATOM   1567 C CB  . GLU A 1 178 ? 4.64832   14.35870 -30.79869 1.000 65.80012  ? 178 GLU A CB  1 
ATOM   1568 C CG  . GLU A 1 178 ? 4.19459   14.63737 -32.22408 1.000 74.94486  ? 178 GLU A CG  1 
ATOM   1569 C CD  . GLU A 1 178 ? 2.86041   15.36618 -32.27957 1.000 83.94778  ? 178 GLU A CD  1 
ATOM   1570 O OE1 . GLU A 1 178 ? 1.97707   15.07121 -31.43995 1.000 85.69720  ? 178 GLU A OE1 1 
ATOM   1571 O OE2 . GLU A 1 178 ? 2.69744   16.22852 -33.17365 1.000 87.50136  ? 178 GLU A OE2 1 
ATOM   1572 N N   . MET A 1 179 ? 6.26624   12.55751 -28.43373 1.000 45.79719  ? 179 MET A N   1 
ATOM   1573 C CA  . MET A 1 179 ? 6.74777   12.63004 -27.06700 1.000 40.82614  ? 179 MET A CA  1 
ATOM   1574 C C   . MET A 1 179 ? 7.98493   11.75960 -26.86259 1.000 33.69233  ? 179 MET A C   1 
ATOM   1575 O O   . MET A 1 179 ? 8.46577   11.62108 -25.72962 1.000 33.30263  ? 179 MET A O   1 
ATOM   1576 C CB  . MET A 1 179 ? 5.63019   12.21106 -26.11736 1.000 48.34078  ? 179 MET A CB  1 
ATOM   1577 C CG  . MET A 1 179 ? 4.57119   13.29808 -25.96348 1.000 59.23420  ? 179 MET A CG  1 
ATOM   1578 S SD  . MET A 1 179 ? 4.85690   14.40822 -24.58915 1.000 66.77905  ? 179 MET A SD  1 
ATOM   1579 C CE  . MET A 1 179 ? 4.55395   13.31081 -23.20538 1.000 65.40053  ? 179 MET A CE  1 
ATOM   1580 N N   . THR A 1 180 ? 8.50538   11.17725 -27.94177 1.000 31.66092  ? 180 THR A N   1 
ATOM   1581 C CA  . THR A 1 180 ? 9.63506   10.25142 -27.90377 1.000 32.99142  ? 180 THR A CA  1 
ATOM   1582 C C   . THR A 1 180 ? 10.96544  10.97702 -28.06983 1.000 33.56394  ? 180 THR A C   1 
ATOM   1583 O O   . THR A 1 180 ? 11.10614  11.82658 -28.95744 1.000 33.26846  ? 180 THR A O   1 
ATOM   1584 C CB  . THR A 1 180 ? 9.46868   9.21441  -29.01945 1.000 32.89024  ? 180 THR A CB  1 
ATOM   1585 O OG1 . THR A 1 180 ? 8.18209   8.60850  -28.89941 1.000 35.73335  ? 180 THR A OG1 1 
ATOM   1586 C CG2 . THR A 1 180 ? 10.56781  8.15194  -29.00015 1.000 35.54497  ? 180 THR A CG2 1 
ATOM   1587 N N   . GLY A 1 181 ? 11.94259  10.63216 -27.22604 1.000 33.06351  ? 181 GLY A N   1 
ATOM   1588 C CA  . GLY A 1 181 ? 13.30696  11.08415 -27.44232 1.000 32.11426  ? 181 GLY A CA  1 
ATOM   1589 C C   . GLY A 1 181 ? 13.70615  12.38242 -26.77291 1.000 32.19493  ? 181 GLY A C   1 
ATOM   1590 O O   . GLY A 1 181 ? 13.15754  12.76001 -25.73667 1.000 32.99341  ? 181 GLY A O   1 
ATOM   1591 N N   . TYR A 1 182 ? 14.68279  13.07539 -27.36582 1.000 31.18548  ? 182 TYR A N   1 
ATOM   1592 C CA  . TYR A 1 182 ? 15.25019  14.30111 -26.79631 1.000 28.82156  ? 182 TYR A CA  1 
ATOM   1593 C C   . TYR A 1 182 ? 14.41957  15.47862 -27.30675 1.000 30.33520  ? 182 TYR A C   1 
ATOM   1594 O O   . TYR A 1 182 ? 14.77424  16.15282 -28.27833 1.000 33.78988  ? 182 TYR A O   1 
ATOM   1595 C CB  . TYR A 1 182 ? 16.72157  14.40621 -27.19222 1.000 28.33566  ? 182 TYR A CB  1 
ATOM   1596 C CG  . TYR A 1 182 ? 17.51199  15.52230 -26.52558 1.000 29.05656  ? 182 TYR A CG  1 
ATOM   1597 C CD1 . TYR A 1 182 ? 17.87251  15.44313 -25.18807 1.000 27.87468  ? 182 TYR A CD1 1 
ATOM   1598 C CD2 . TYR A 1 182 ? 17.88565  16.65338 -27.23799 1.000 29.84725  ? 182 TYR A CD2 1 
ATOM   1599 C CE1 . TYR A 1 182 ? 18.58446  16.46604 -24.57018 1.000 27.03128  ? 182 TYR A CE1 1 
ATOM   1600 C CE2 . TYR A 1 182 ? 18.59139  17.66973 -26.64275 1.000 32.76008  ? 182 TYR A CE2 1 
ATOM   1601 C CZ  . TYR A 1 182 ? 18.93920  17.57885 -25.30617 1.000 32.03682  ? 182 TYR A CZ  1 
ATOM   1602 O OH  . TYR A 1 182 ? 19.66028  18.58754 -24.70985 1.000 34.71622  ? 182 TYR A OH  1 
ATOM   1603 N N   . VAL A 1 183 ? 13.26460  15.70680 -26.65496 1.000 31.27245  ? 183 VAL A N   1 
ATOM   1604 C CA  . VAL A 1 183 ? 12.25394  16.62213 -27.18452 1.000 34.03605  ? 183 VAL A CA  1 
ATOM   1605 C C   . VAL A 1 183 ? 11.70267  17.50649 -26.07023 1.000 33.23154  ? 183 VAL A C   1 
ATOM   1606 O O   . VAL A 1 183 ? 11.31170  17.00877 -25.00887 1.000 32.23310  ? 183 VAL A O   1 
ATOM   1607 C CB  . VAL A 1 183 ? 11.09972  15.86503 -27.88505 1.000 33.01413  ? 183 VAL A CB  1 
ATOM   1608 C CG1 . VAL A 1 183 ? 11.53755  15.34146 -29.25804 1.000 34.69252  ? 183 VAL A CG1 1 
ATOM   1609 C CG2 . VAL A 1 183 ? 10.54706  14.72372 -27.01334 1.000 32.28800  ? 183 VAL A CG2 1 
ATOM   1610 N N   . ALA A 1 184 ? 11.63057  18.82234 -26.32904 1.000 32.00981  ? 184 ALA A N   1 
ATOM   1611 C CA  . ALA A 1 184 ? 11.02194  19.73539 -25.36048 1.000 33.57228  ? 184 ALA A CA  1 
ATOM   1612 C C   . ALA A 1 184 ? 9.54542   19.43792 -25.12330 1.000 35.83277  ? 184 ALA A C   1 
ATOM   1613 O O   . ALA A 1 184 ? 8.98086   19.91663 -24.12738 1.000 38.98089  ? 184 ALA A O   1 
ATOM   1614 C CB  . ALA A 1 184 ? 11.18429  21.19195 -25.81874 1.000 35.47834  ? 184 ALA A CB  1 
ATOM   1615 N N   . THR A 1 185 ? 8.91212   18.65190 -25.99018 1.000 33.99956  ? 185 THR A N   1 
ATOM   1616 C CA  . THR A 1 185 ? 7.51478   18.30420 -25.75432 1.000 35.45170  ? 185 THR A CA  1 
ATOM   1617 C C   . THR A 1 185 ? 7.32474   17.49516 -24.47643 1.000 36.01270  ? 185 THR A C   1 
ATOM   1618 O O   . THR A 1 185 ? 6.18709   17.37319 -24.01337 1.000 38.88147  ? 185 THR A O   1 
ATOM   1619 C CB  . THR A 1 185 ? 6.94923   17.51041 -26.92682 1.000 39.58043  ? 185 THR A CB  1 
ATOM   1620 O OG1 . THR A 1 185 ? 7.84100   16.43322 -27.23496 1.000 39.93993  ? 185 THR A OG1 1 
ATOM   1621 C CG2 . THR A 1 185 ? 6.81642   18.40118 -28.15173 1.000 40.98130  ? 185 THR A CG2 1 
ATOM   1622 N N   . ARG A 1 186 ? 8.39468   16.91935 -23.90954 1.000 29.12901  ? 186 ARG A N   1 
ATOM   1623 C CA  . ARG A 1 186 ? 8.28321   16.10665 -22.70635 1.000 29.15248  ? 186 ARG A CA  1 
ATOM   1624 C C   . ARG A 1 186 ? 9.02694   16.67375 -21.50842 1.000 27.55638  ? 186 ARG A C   1 
ATOM   1625 O O   . ARG A 1 186 ? 8.70556   16.29474 -20.37341 1.000 28.46241  ? 186 ARG A O   1 
ATOM   1626 C CB  . ARG A 1 186 ? 8.77110   14.66943 -22.99069 1.000 26.83892  ? 186 ARG A CB  1 
ATOM   1627 C CG  . ARG A 1 186 ? 8.20671   13.57048 -22.07006 1.000 28.21527  ? 186 ARG A CG  1 
ATOM   1628 C CD  . ARG A 1 186 ? 8.93383   12.24441 -22.27267 1.000 27.78742  ? 186 ARG A CD  1 
ATOM   1629 N NE  . ARG A 1 186 ? 10.37213  12.43043 -22.09032 1.000 28.35442  ? 186 ARG A NE  1 
ATOM   1630 C CZ  . ARG A 1 186 ? 11.25676  12.42509 -23.07219 1.000 28.53892  ? 186 ARG A CZ  1 
ATOM   1631 N NH1 . ARG A 1 186 ? 10.93200  12.01749 -24.29335 1.000 29.93334  ? 186 ARG A NH1 1 
ATOM   1632 N NH2 . ARG A 1 186 ? 12.49579  12.85172 -22.83139 1.000 26.86446  ? 186 ARG A NH2 1 
ATOM   1633 N N   . TRP A 1 187 ? 9.96453   17.60269 -21.71326 1.000 25.57643  ? 187 TRP A N   1 
ATOM   1634 C CA  . TRP A 1 187 ? 10.86106  18.03178 -20.63281 1.000 25.03125  ? 187 TRP A CA  1 
ATOM   1635 C C   . TRP A 1 187 ? 10.15875  18.75604 -19.49169 1.000 28.14039  ? 187 TRP A C   1 
ATOM   1636 O O   . TRP A 1 187 ? 10.72296  18.83646 -18.38792 1.000 27.97640  ? 187 TRP A O   1 
ATOM   1637 C CB  . TRP A 1 187 ? 11.95382  18.94653 -21.19299 1.000 24.38256  ? 187 TRP A CB  1 
ATOM   1638 C CG  . TRP A 1 187 ? 12.88046  18.24723 -22.12837 1.000 24.35023  ? 187 TRP A CG  1 
ATOM   1639 C CD1 . TRP A 1 187 ? 13.15143  16.89969 -22.17520 1.000 26.98467  ? 187 TRP A CD1 1 
ATOM   1640 C CD2 . TRP A 1 187 ? 13.68594  18.85958 -23.13656 1.000 28.74004  ? 187 TRP A CD2 1 
ATOM   1641 N NE1 . TRP A 1 187 ? 14.08114  16.64127 -23.16565 1.000 26.14805  ? 187 TRP A NE1 1 
ATOM   1642 C CE2 . TRP A 1 187 ? 14.41613  17.83053 -23.77764 1.000 27.52968  ? 187 TRP A CE2 1 
ATOM   1643 C CE3 . TRP A 1 187 ? 13.85368  20.18299 -23.56812 1.000 28.65165  ? 187 TRP A CE3 1 
ATOM   1644 C CZ2 . TRP A 1 187 ? 15.30542  18.08924 -24.82733 1.000 31.91941  ? 187 TRP A CZ2 1 
ATOM   1645 C CZ3 . TRP A 1 187 ? 14.74243  20.43979 -24.60631 1.000 32.42410  ? 187 TRP A CZ3 1 
ATOM   1646 C CH2 . TRP A 1 187 ? 15.44110  19.39535 -25.24115 1.000 31.08573  ? 187 TRP A CH2 1 
ATOM   1647 N N   . TYR A 1 188 ? 8.95111   19.27761 -19.71642 1.000 25.25994  ? 188 TYR A N   1 
ATOM   1648 C CA  . TYR A 1 188 ? 8.24686   20.04776 -18.70200 1.000 26.74468  ? 188 TYR A CA  1 
ATOM   1649 C C   . TYR A 1 188 ? 7.10569   19.26482 -18.06150 1.000 27.86120  ? 188 TYR A C   1 
ATOM   1650 O O   . TYR A 1 188 ? 6.41384   19.80434 -17.20287 1.000 28.01699  ? 188 TYR A O   1 
ATOM   1651 C CB  . TYR A 1 188 ? 7.74679   21.37366 -19.31534 1.000 26.03943  ? 188 TYR A CB  1 
ATOM   1652 C CG  . TYR A 1 188 ? 8.88594   22.11932 -19.97672 1.000 24.24440  ? 188 TYR A CG  1 
ATOM   1653 C CD1 . TYR A 1 188 ? 9.22910   21.86593 -21.30894 1.000 28.35661  ? 188 TYR A CD1 1 
ATOM   1654 C CD2 . TYR A 1 188 ? 9.65804   23.03485 -19.26114 1.000 27.37682  ? 188 TYR A CD2 1 
ATOM   1655 C CE1 . TYR A 1 188 ? 10.30353  22.52182 -21.91251 1.000 28.03719  ? 188 TYR A CE1 1 
ATOM   1656 C CE2 . TYR A 1 188 ? 10.73345  23.70196 -19.85970 1.000 28.35141  ? 188 TYR A CE2 1 
ATOM   1657 C CZ  . TYR A 1 188 ? 11.05589  23.43150 -21.17539 1.000 28.74710  ? 188 TYR A CZ  1 
ATOM   1658 O OH  . TYR A 1 188 ? 12.11784  24.09961 -21.77377 1.000 28.86047  ? 188 TYR A OH  1 
ATOM   1659 N N   . ARG A 1 189 ? 6.90949   18.00199 -18.43499 1.000 28.61495  ? 189 ARG A N   1 
ATOM   1660 C CA  . ARG A 1 189 ? 5.77932   17.23879 -17.91448 1.000 29.51165  ? 189 ARG A CA  1 
ATOM   1661 C C   . ARG A 1 189 ? 6.07883   16.62255 -16.55211 1.000 28.22255  ? 189 ARG A C   1 
ATOM   1662 O O   . ARG A 1 189 ? 7.18202   16.12002 -16.30925 1.000 28.88655  ? 189 ARG A O   1 
ATOM   1663 C CB  . ARG A 1 189 ? 5.37728   16.14207 -18.89371 1.000 34.60225  ? 189 ARG A CB  1 
ATOM   1664 C CG  . ARG A 1 189 ? 5.07201   16.65249 -20.28687 1.000 45.54384  ? 189 ARG A CG  1 
ATOM   1665 C CD  . ARG A 1 189 ? 4.57194   15.51722 -21.13704 1.000 57.00091  ? 189 ARG A CD  1 
ATOM   1666 N NE  . ARG A 1 189 ? 3.15176   15.26013 -20.94094 1.000 66.09926  ? 189 ARG A NE  1 
ATOM   1667 C CZ  . ARG A 1 189 ? 2.18375   15.95836 -21.51487 1.000 69.29139  ? 189 ARG A CZ  1 
ATOM   1668 N NH1 . ARG A 1 189 ? 2.44828   16.99149 -22.29853 1.000 70.41477  ? 189 ARG A NH1 1 
ATOM   1669 N NH2 . ARG A 1 189 ? 0.92131   15.60616 -21.30510 1.000 72.31522  ? 189 ARG A NH2 1 
ATOM   1670 N N   . ALA A 1 190 ? 5.07330   16.64975 -15.67688 1.000 29.62882  ? 190 ALA A N   1 
ATOM   1671 C CA  . ALA A 1 190 ? 5.19374   16.01779 -14.36915 1.000 28.70039  ? 190 ALA A CA  1 
ATOM   1672 C C   . ALA A 1 190 ? 5.42181   14.52123 -14.55638 1.000 31.85614  ? 190 ALA A C   1 
ATOM   1673 O O   . ALA A 1 190 ? 4.86878   13.92696 -15.48452 1.000 31.52052  ? 190 ALA A O   1 
ATOM   1674 C CB  . ALA A 1 190 ? 3.93025   16.23800 -13.52728 1.000 29.92473  ? 190 ALA A CB  1 
ATOM   1675 N N   . PRO A 1 191 ? 6.21384   13.88278 -13.69460 1.000 31.37809  ? 191 PRO A N   1 
ATOM   1676 C CA  . PRO A 1 191 ? 6.47045   12.45035 -13.88068 1.000 32.27925  ? 191 PRO A CA  1 
ATOM   1677 C C   . PRO A 1 191 ? 5.20659   11.59964 -13.83915 1.000 34.31214  ? 191 PRO A C   1 
ATOM   1678 O O   . PRO A 1 191 ? 5.12375   10.60356 -14.56889 1.000 34.76805  ? 191 PRO A O   1 
ATOM   1679 C CB  . PRO A 1 191 ? 7.43696   12.10784 -12.73758 1.000 35.08800  ? 191 PRO A CB  1 
ATOM   1680 C CG  . PRO A 1 191 ? 7.32288   13.22709 -11.74246 1.000 36.65743  ? 191 PRO A CG  1 
ATOM   1681 C CD  . PRO A 1 191 ? 6.92333   14.44758 -12.53225 1.000 32.00731  ? 191 PRO A CD  1 
ATOM   1682 N N   A GLU A 1 192 ? 4.21179   11.96667 -13.02251 0.830 32.72567  ? 192 GLU A N   1 
ATOM   1683 N N   B GLU A 1 192 ? 4.22941   11.95172 -13.00197 0.170 34.50689  ? 192 GLU A N   1 
ATOM   1684 C CA  A GLU A 1 192 ? 3.00396   11.14708 -12.93296 0.830 31.58465  ? 192 GLU A CA  1 
ATOM   1685 C CA  B GLU A 1 192 ? 2.99796   11.17086 -12.94097 0.170 35.69663  ? 192 GLU A CA  1 
ATOM   1686 C C   A GLU A 1 192 ? 2.20595   11.16405 -14.24001 0.830 39.09555  ? 192 GLU A C   1 
ATOM   1687 C C   B GLU A 1 192 ? 2.30723   11.12061 -14.29898 0.170 37.64071  ? 192 GLU A C   1 
ATOM   1688 O O   A GLU A 1 192 ? 1.47312   10.20855 -14.52647 0.830 37.94188  ? 192 GLU A O   1 
ATOM   1689 O O   B GLU A 1 192 ? 1.74826   10.08625 -14.68219 0.170 38.32136  ? 192 GLU A O   1 
ATOM   1690 C CB  A GLU A 1 192 ? 2.13415   11.60076 -11.75110 0.830 33.11692  ? 192 GLU A CB  1 
ATOM   1691 C CB  B GLU A 1 192 ? 2.06381   11.75261 -11.88023 0.170 36.41014  ? 192 GLU A CB  1 
ATOM   1692 C CG  A GLU A 1 192 ? 1.47690   12.97192 -11.93611 0.830 33.82569  ? 192 GLU A CG  1 
ATOM   1693 C CG  B GLU A 1 192 ? 1.85382   13.25349 -12.01451 0.170 37.03678  ? 192 GLU A CG  1 
ATOM   1694 C CD  A GLU A 1 192 ? 2.22721   14.08733 -11.22038 0.830 35.22661  ? 192 GLU A CD  1 
ATOM   1695 C CD  B GLU A 1 192 ? 2.78785   14.04845 -11.12331 0.170 36.22764  ? 192 GLU A CD  1 
ATOM   1696 O OE1 A GLU A 1 192 ? 3.42972   13.89896 -10.93617 0.830 37.42536  ? 192 GLU A OE1 1 
ATOM   1697 O OE1 B GLU A 1 192 ? 3.97471   13.67088 -11.02621 0.170 33.14041  ? 192 GLU A OE1 1 
ATOM   1698 O OE2 A GLU A 1 192 ? 1.63213   15.15856 -10.97540 0.830 30.56070  ? 192 GLU A OE2 1 
ATOM   1699 O OE2 B GLU A 1 192 ? 2.34035   15.05600 -10.53503 0.170 37.24427  ? 192 GLU A OE2 1 
ATOM   1700 N N   . ILE A 1 193 ? 2.33102   12.22965 -15.03753 1.000 37.47841  ? 193 ILE A N   1 
ATOM   1701 C CA  . ILE A 1 193 ? 1.73323   12.26102 -16.37203 1.000 39.54263  ? 193 ILE A CA  1 
ATOM   1702 C C   . ILE A 1 193 ? 2.62406   11.54530 -17.37974 1.000 37.25522  ? 193 ILE A C   1 
ATOM   1703 O O   . ILE A 1 193 ? 2.14505   10.76017 -18.20733 1.000 41.24774  ? 193 ILE A O   1 
ATOM   1704 C CB  . ILE A 1 193 ? 1.48915   13.71637 -16.81003 1.000 48.97882  ? 193 ILE A CB  1 
ATOM   1705 C CG1 . ILE A 1 193 ? 0.40631   14.37820 -15.98141 1.000 58.21427  ? 193 ILE A CG1 1 
ATOM   1706 C CG2 . ILE A 1 193 ? 1.09170   13.76749 -18.28268 1.000 56.22062  ? 193 ILE A CG2 1 
ATOM   1707 C CD1 . ILE A 1 193 ? -0.94003  14.32816 -16.66734 1.000 63.71378  ? 193 ILE A CD1 1 
ATOM   1708 N N   . MET A 1 194 ? 3.92682   11.85157 -17.34789 1.000 35.67102  ? 194 MET A N   1 
ATOM   1709 C CA  . MET A 1 194 ? 4.91161   11.23045 -18.23621 1.000 34.40392  ? 194 MET A CA  1 
ATOM   1710 C C   . MET A 1 194 ? 4.74149   9.72079  -18.31176 1.000 35.85587  ? 194 MET A C   1 
ATOM   1711 O O   . MET A 1 194 ? 4.76927   9.13212  -19.39886 1.000 38.78638  ? 194 MET A O   1 
ATOM   1712 C CB  . MET A 1 194 ? 6.32078   11.50753 -17.71096 1.000 34.42534  ? 194 MET A CB  1 
ATOM   1713 C CG  . MET A 1 194 ? 7.41133   10.96597 -18.57075 1.000 35.54152  ? 194 MET A CG  1 
ATOM   1714 S SD  . MET A 1 194 ? 8.84285   12.02990 -18.56094 1.000 35.70642  ? 194 MET A SD  1 
ATOM   1715 C CE  . MET A 1 194 ? 9.49135   11.30638 -17.03649 1.000 34.00789  ? 194 MET A CE  1 
ATOM   1716 N N   A LEU A 1 195 ? 4.58600   9.07219  -17.15568 0.500 34.76406  ? 195 LEU A N   1 
ATOM   1717 N N   B LEU A 1 195 ? 4.60245   9.07271  -17.15173 0.500 34.52073  ? 195 LEU A N   1 
ATOM   1718 C CA  A LEU A 1 195 ? 4.60324   7.61683  -17.05876 0.500 37.44176  ? 195 LEU A CA  1 
ATOM   1719 C CA  B LEU A 1 195 ? 4.60157   7.61788  -17.04652 0.500 36.47190  ? 195 LEU A CA  1 
ATOM   1720 C C   A LEU A 1 195 ? 3.24012   7.01877  -16.73854 0.500 38.55712  ? 195 LEU A C   1 
ATOM   1721 C C   B LEU A 1 195 ? 3.25947   7.05214  -16.59687 0.500 37.40563  ? 195 LEU A C   1 
ATOM   1722 O O   A LEU A 1 195 ? 3.15307   5.80951  -16.51437 0.500 39.36953  ? 195 LEU A O   1 
ATOM   1723 O O   B LEU A 1 195 ? 3.20549   5.90308  -16.14943 0.500 35.94180  ? 195 LEU A O   1 
ATOM   1724 C CB  A LEU A 1 195 ? 5.61212   7.15767  -15.99986 0.500 37.57645  ? 195 LEU A CB  1 
ATOM   1725 C CB  B LEU A 1 195 ? 5.70185   7.13933  -16.09343 0.500 34.70226  ? 195 LEU A CB  1 
ATOM   1726 C CG  A LEU A 1 195 ? 7.09894   7.39971  -16.27360 0.500 41.18761  ? 195 LEU A CG  1 
ATOM   1727 C CG  B LEU A 1 195 ? 7.13091   7.63616  -16.30313 0.500 34.03349  ? 195 LEU A CG  1 
ATOM   1728 C CD1 A LEU A 1 195 ? 7.34108   7.54027  -17.76486 0.500 39.39211  ? 195 LEU A CD1 1 
ATOM   1729 C CD1 B LEU A 1 195 ? 7.96147   7.44182  -15.03930 0.500 32.23335  ? 195 LEU A CD1 1 
ATOM   1730 C CD2 A LEU A 1 195 ? 7.62536   8.59990  -15.50971 0.500 43.75425  ? 195 LEU A CD2 1 
ATOM   1731 C CD2 B LEU A 1 195 ? 7.72552   6.84322  -17.44410 0.500 32.72101  ? 195 LEU A CD2 1 
ATOM   1732 N N   . ASN A 1 196 ? 2.18200   7.82836  -16.70181 1.000 41.16368  ? 196 ASN A N   1 
ATOM   1733 C CA  . ASN A 1 196 ? 0.83031   7.35189  -16.36331 1.000 47.93257  ? 196 ASN A CA  1 
ATOM   1734 C C   . ASN A 1 196 ? 0.80797   6.61327  -15.02679 1.000 41.78153  ? 196 ASN A C   1 
ATOM   1735 O O   . ASN A 1 196 ? 0.33740   5.48289  -14.91829 1.000 43.30423  ? 196 ASN A O   1 
ATOM   1736 C CB  . ASN A 1 196 ? 0.26469   6.46924  -17.47644 1.000 56.42885  ? 196 ASN A CB  1 
ATOM   1737 C CG  . ASN A 1 196 ? -0.00289  7.24117  -18.74480 1.000 69.28632  ? 196 ASN A CG  1 
ATOM   1738 O OD1 . ASN A 1 196 ? 0.91919   7.56788  -19.49602 1.000 73.82348  ? 196 ASN A OD1 1 
ATOM   1739 N ND2 . ASN A 1 196 ? -1.27408  7.53496  -18.99935 1.000 73.84827  ? 196 ASN A ND2 1 
ATOM   1740 N N   . TRP A 1 197 ? 1.31861   7.27448  -13.98929 1.000 39.50220  ? 197 TRP A N   1 
ATOM   1741 C CA  . TRP A 1 197 ? 1.36075   6.65247  -12.67041 1.000 37.67421  ? 197 TRP A CA  1 
ATOM   1742 C C   . TRP A 1 197 ? -0.01355  6.57040  -12.02758 1.000 40.87197  ? 197 TRP A C   1 
ATOM   1743 O O   . TRP A 1 197 ? -0.27308  5.66404  -11.22910 1.000 43.73353  ? 197 TRP A O   1 
ATOM   1744 C CB  . TRP A 1 197 ? 2.28216   7.44780  -11.75093 1.000 42.21215  ? 197 TRP A CB  1 
ATOM   1745 C CG  . TRP A 1 197 ? 3.72065   7.18670  -11.91370 1.000 40.69725  ? 197 TRP A CG  1 
ATOM   1746 C CD1 . TRP A 1 197 ? 4.31433   6.27546  -12.74076 1.000 41.83899  ? 197 TRP A CD1 1 
ATOM   1747 C CD2 . TRP A 1 197 ? 4.78178   7.89164  -11.26441 1.000 41.42641  ? 197 TRP A CD2 1 
ATOM   1748 N NE1 . TRP A 1 197 ? 5.68889   6.34856  -12.61751 1.000 40.83119  ? 197 TRP A NE1 1 
ATOM   1749 C CE2 . TRP A 1 197 ? 5.99759   7.33650  -11.72054 1.000 38.33533  ? 197 TRP A CE2 1 
ATOM   1750 C CE3 . TRP A 1 197 ? 4.82130   8.93473  -10.33489 1.000 43.13627  ? 197 TRP A CE3 1 
ATOM   1751 C CZ2 . TRP A 1 197 ? 7.23543   7.78652  -11.27401 1.000 41.86751  ? 197 TRP A CZ2 1 
ATOM   1752 C CZ3 . TRP A 1 197 ? 6.05822   9.37972  -9.89208  1.000 44.69046  ? 197 TRP A CZ3 1 
ATOM   1753 C CH2 . TRP A 1 197 ? 7.24402   8.81035  -10.36747 1.000 44.14122  ? 197 TRP A CH2 1 
ATOM   1754 N N   . MET A 1 198 ? -0.89023  7.51715  -12.32845 1.000 43.70851  ? 198 MET A N   1 
ATOM   1755 C CA  . MET A 1 198 ? -2.04965  7.74823  -11.48488 1.000 48.98441  ? 198 MET A CA  1 
ATOM   1756 C C   . MET A 1 198 ? -2.92129  8.79956  -12.14707 1.000 54.34678  ? 198 MET A C   1 
ATOM   1757 O O   . MET A 1 198 ? -2.51806  9.45252  -13.11234 1.000 49.85165  ? 198 MET A O   1 
ATOM   1758 C CB  . MET A 1 198 ? -1.60655  8.17730  -10.08051 1.000 51.89566  ? 198 MET A CB  1 
ATOM   1759 C CG  . MET A 1 198 ? -1.08828  9.60199  -10.01124 1.000 55.32263  ? 198 MET A CG  1 
ATOM   1760 S SD  . MET A 1 198 ? -0.40087  10.03612 -8.39621  1.000 55.95192  ? 198 MET A SD  1 
ATOM   1761 C CE  . MET A 1 198 ? 1.11794   9.11392  -8.35771  1.000 49.66857  ? 198 MET A CE  1 
ATOM   1762 N N   . HIS A 1 199 ? -4.13249  8.94174  -11.62172 1.000 62.63657  ? 199 HIS A N   1 
ATOM   1763 C CA  . HIS A 1 199 ? -5.03285  9.98520  -12.08597 1.000 71.48856  ? 199 HIS A CA  1 
ATOM   1764 C C   . HIS A 1 199 ? -4.51954  11.32350 -11.57221 1.000 66.70904  ? 199 HIS A C   1 
ATOM   1765 O O   . HIS A 1 199 ? -4.42297  11.53117 -10.35921 1.000 72.89304  ? 199 HIS A O   1 
ATOM   1766 C CB  . HIS A 1 199 ? -6.44820  9.70252  -11.59342 1.000 83.75150  ? 199 HIS A CB  1 
ATOM   1767 C CG  . HIS A 1 199 ? -7.14367  8.62574  -12.36791 1.000 94.11529  ? 199 HIS A CG  1 
ATOM   1768 N ND1 . HIS A 1 199 ? -6.87235  8.37180  -13.69537 1.000 99.68166  ? 199 HIS A ND1 1 
ATOM   1769 C CD2 . HIS A 1 199 ? -8.06920  7.71075  -11.99242 1.000 96.89036  ? 199 HIS A CD2 1 
ATOM   1770 C CE1 . HIS A 1 199 ? -7.61590  7.36179  -14.11074 1.000 100.79816 ? 199 HIS A CE1 1 
ATOM   1771 N NE2 . HIS A 1 199 ? -8.35062  6.94179  -13.09641 1.000 99.62669  ? 199 HIS A NE2 1 
ATOM   1772 N N   . TYR A 1 200 ? -4.16884  12.21974 -12.48734 1.000 57.09071  ? 200 TYR A N   1 
ATOM   1773 C CA  . TYR A 1 200 ? -3.42564  13.41991 -12.13323 1.000 59.47773  ? 200 TYR A CA  1 
ATOM   1774 C C   . TYR A 1 200 ? -4.34623  14.59559 -11.83689 1.000 59.95907  ? 200 TYR A C   1 
ATOM   1775 O O   . TYR A 1 200 ? -5.48319  14.66162 -12.31250 1.000 64.17692  ? 200 TYR A O   1 
ATOM   1776 C CB  . TYR A 1 200 ? -2.46610  13.80429 -13.25537 1.000 60.03373  ? 200 TYR A CB  1 
ATOM   1777 C CG  . TYR A 1 200 ? -3.18249  14.09971 -14.54079 1.000 60.46191  ? 200 TYR A CG  1 
ATOM   1778 C CD1 . TYR A 1 200 ? -3.56214  13.07611 -15.39453 1.000 67.82171  ? 200 TYR A CD1 1 
ATOM   1779 C CD2 . TYR A 1 200 ? -3.53536  15.39575 -14.87327 1.000 63.13081  ? 200 TYR A CD2 1 
ATOM   1780 C CE1 . TYR A 1 200 ? -4.22988  13.34416 -16.57096 1.000 74.80261  ? 200 TYR A CE1 1 
ATOM   1781 C CE2 . TYR A 1 200 ? -4.20413  15.67357 -16.04159 1.000 69.15042  ? 200 TYR A CE2 1 
ATOM   1782 C CZ  . TYR A 1 200 ? -4.55296  14.64566 -16.88892 1.000 76.68048  ? 200 TYR A CZ  1 
ATOM   1783 O OH  . TYR A 1 200 ? -5.22861  14.91958 -18.05771 1.000 82.85184  ? 200 TYR A OH  1 
ATOM   1784 N N   . ASN A 1 201 ? -3.83225  15.53901 -11.05563 1.000 55.48915  ? 201 ASN A N   1 
ATOM   1785 C CA  . ASN A 1 201 ? -4.57834  16.72845 -10.67274 1.000 53.13010  ? 201 ASN A CA  1 
ATOM   1786 C C   . ASN A 1 201 ? -3.93789  17.98445 -11.26231 1.000 42.50358  ? 201 ASN A C   1 
ATOM   1787 O O   . ASN A 1 201 ? -2.99749  17.93870 -12.05920 1.000 37.92929  ? 201 ASN A O   1 
ATOM   1788 C CB  . ASN A 1 201 ? -4.74977  16.78575 -9.14397  1.000 56.32811  ? 201 ASN A CB  1 
ATOM   1789 C CG  . ASN A 1 201 ? -3.45887  17.08868 -8.38634  1.000 58.60418  ? 201 ASN A CG  1 
ATOM   1790 O OD1 . ASN A 1 201 ? -2.50395  17.62931 -8.91991  1.000 65.09639  ? 201 ASN A OD1 1 
ATOM   1791 N ND2 . ASN A 1 201 ? -3.44088  16.71638 -7.10885  1.000 60.79817  ? 201 ASN A ND2 1 
ATOM   1792 N N   . GLN A 1 202 ? -4.50007  19.13108 -10.90738 1.000 38.80357  ? 202 GLN A N   1 
ATOM   1793 C CA  . GLN A 1 202 ? -4.03136  20.35314 -11.53762 1.000 35.67469  ? 202 GLN A CA  1 
ATOM   1794 C C   . GLN A 1 202 ? -2.62315  20.73456 -11.10271 1.000 28.86322  ? 202 GLN A C   1 
ATOM   1795 O O   . GLN A 1 202 ? -1.99276  21.56933 -11.76644 1.000 28.75899  ? 202 GLN A O   1 
ATOM   1796 C CB  . GLN A 1 202 ? -5.07789  21.43459 -11.29248 1.000 45.85865  ? 202 GLN A CB  1 
ATOM   1797 C CG  . GLN A 1 202 ? -5.31730  21.79885 -9.86971  1.000 50.01881  ? 202 GLN A CG  1 
ATOM   1798 C CD  . GLN A 1 202 ? -6.66591  22.51888 -9.71897  1.000 49.19552  ? 202 GLN A CD  1 
ATOM   1799 O OE1 . GLN A 1 202 ? -7.60875  22.25014 -10.45861 1.000 58.06984  ? 202 GLN A OE1 1 
ATOM   1800 N NE2 . GLN A 1 202 ? -6.75488  23.41315 -8.75787  1.000 47.84880  ? 202 GLN A NE2 1 
ATOM   1801 N N   . THR A 1 203 ? -2.10034  20.08188 -10.06159 1.000 33.45976  ? 203 THR A N   1 
ATOM   1802 C CA  . THR A 1 203 ? -0.69465  20.19037 -9.68253  1.000 36.67743  ? 203 THR A CA  1 
ATOM   1803 C C   . THR A 1 203 ? 0.29200   19.83020 -10.78489 1.000 32.44484  ? 203 THR A C   1 
ATOM   1804 O O   . THR A 1 203 ? 1.47459   20.20026 -10.68040 1.000 30.00525  ? 203 THR A O   1 
ATOM   1805 C CB  . THR A 1 203 ? -0.41349  19.27686 -8.48524  1.000 45.31982  ? 203 THR A CB  1 
ATOM   1806 O OG1 . THR A 1 203 ? -1.55595  19.24765 -7.61664  1.000 61.00760  ? 203 THR A OG1 1 
ATOM   1807 C CG2 . THR A 1 203 ? 0.78219   19.70453 -7.77468  1.000 51.43255  ? 203 THR A CG2 1 
ATOM   1808 N N   . VAL A 1 204 ? -0.11849  19.07403 -11.80596 1.000 33.06508  ? 204 VAL A N   1 
ATOM   1809 C CA  . VAL A 1 204 ? 0.81478   18.82182 -12.90371 1.000 32.11825  ? 204 VAL A CA  1 
ATOM   1810 C C   . VAL A 1 204 ? 1.30955   20.13566 -13.47975 1.000 30.53746  ? 204 VAL A C   1 
ATOM   1811 O O   . VAL A 1 204 ? 2.45365   20.23707 -13.92605 1.000 31.00819  ? 204 VAL A O   1 
ATOM   1812 C CB  . VAL A 1 204 ? 0.18896   17.94455 -14.00603 1.000 30.15331  ? 204 VAL A CB  1 
ATOM   1813 C CG1 . VAL A 1 204 ? -0.14114  16.58535 -13.45970 1.000 30.53429  ? 204 VAL A CG1 1 
ATOM   1814 C CG2 . VAL A 1 204 ? -1.03605  18.62838 -14.59200 1.000 34.88949  ? 204 VAL A CG2 1 
ATOM   1815 N N   . ASP A 1 205 ? 0.44440   21.15248 -13.51680 1.000 27.72117  ? 205 ASP A N   1 
ATOM   1816 C CA  . ASP A 1 205 ? 0.86281   22.43237 -14.07721 1.000 28.00954  ? 205 ASP A CA  1 
ATOM   1817 C C   . ASP A 1 205 ? 1.90980   23.10500 -13.19987 1.000 26.49589  ? 205 ASP A C   1 
ATOM   1818 O O   . ASP A 1 205 ? 2.81486   23.78440 -13.71585 1.000 28.54857  ? 205 ASP A O   1 
ATOM   1819 C CB  . ASP A 1 205 ? -0.35156  23.35773 -14.26901 1.000 27.38954  ? 205 ASP A CB  1 
ATOM   1820 C CG  . ASP A 1 205 ? -1.29409  22.90631 -15.37145 1.000 31.41794  ? 205 ASP A CG  1 
ATOM   1821 O OD1 . ASP A 1 205 ? -0.87495  22.20594 -16.33168 1.000 31.52049  ? 205 ASP A OD1 1 
ATOM   1822 O OD2 . ASP A 1 205 ? -2.47415  23.30875 -15.30176 1.000 29.63035  ? 205 ASP A OD2 1 
ATOM   1823 N N   . ILE A 1 206 ? 1.83040   22.90750 -11.88202 1.000 25.72503  ? 206 ILE A N   1 
ATOM   1824 C CA  . ILE A 1 206 ? 2.81684   23.53372 -11.00487 1.000 24.20958  ? 206 ILE A CA  1 
ATOM   1825 C C   . ILE A 1 206 ? 4.19939   22.91962 -11.23328 1.000 24.37815  ? 206 ILE A C   1 
ATOM   1826 O O   . ILE A 1 206 ? 5.22289   23.61792 -11.19204 1.000 26.97998  ? 206 ILE A O   1 
ATOM   1827 C CB  . ILE A 1 206 ? 2.37228   23.42519 -9.53593  1.000 25.25606  ? 206 ILE A CB  1 
ATOM   1828 C CG1 . ILE A 1 206 ? 1.09544   24.23945 -9.30827  1.000 25.31854  ? 206 ILE A CG1 1 
ATOM   1829 C CG2 . ILE A 1 206 ? 3.47794   23.90483 -8.57405  1.000 30.46481  ? 206 ILE A CG2 1 
ATOM   1830 C CD1 . ILE A 1 206 ? 1.29989   25.75533 -9.42600  1.000 32.61605  ? 206 ILE A CD1 1 
ATOM   1831 N N   . TRP A 1 207 ? 4.26090   21.61288 -11.49567 1.000 27.02044  ? 207 TRP A N   1 
ATOM   1832 C CA  . TRP A 1 207 ? 5.53887   20.99510 -11.85943 1.000 22.50461  ? 207 TRP A CA  1 
ATOM   1833 C C   . TRP A 1 207 ? 6.15999   21.67735 -13.07324 1.000 23.75293  ? 207 TRP A C   1 
ATOM   1834 O O   . TRP A 1 207 ? 7.34988   22.04035 -13.05651 1.000 24.91451  ? 207 TRP A O   1 
ATOM   1835 C CB  . TRP A 1 207 ? 5.34685   19.48418 -12.12872 1.000 24.71858  ? 207 TRP A CB  1 
ATOM   1836 C CG  . TRP A 1 207 ? 6.66865   18.78677 -12.45530 1.000 23.91754  ? 207 TRP A CG  1 
ATOM   1837 C CD1 . TRP A 1 207 ? 7.26045   18.66934 -13.68216 1.000 24.67232  ? 207 TRP A CD1 1 
ATOM   1838 C CD2 . TRP A 1 207 ? 7.54245   18.13974 -11.52497 1.000 26.38973  ? 207 TRP A CD2 1 
ATOM   1839 N NE1 . TRP A 1 207 ? 8.47380   17.99114 -13.56864 1.000 24.54723  ? 207 TRP A NE1 1 
ATOM   1840 C CE2 . TRP A 1 207 ? 8.65883   17.65462 -12.25202 1.000 26.45665  ? 207 TRP A CE2 1 
ATOM   1841 C CE3 . TRP A 1 207 ? 7.48434   17.91444 -10.15248 1.000 24.06359  ? 207 TRP A CE3 1 
ATOM   1842 C CZ2 . TRP A 1 207 ? 9.71052   16.96115 -11.63963 1.000 27.86359  ? 207 TRP A CZ2 1 
ATOM   1843 C CZ3 . TRP A 1 207 ? 8.52801   17.24648 -9.53862  1.000 28.06838  ? 207 TRP A CZ3 1 
ATOM   1844 C CH2 . TRP A 1 207 ? 9.62370   16.75477 -10.29008 1.000 28.19720  ? 207 TRP A CH2 1 
ATOM   1845 N N   . SER A 1 208 ? 5.35801   21.88407 -14.12244 1.000 27.01597  ? 208 SER A N   1 
ATOM   1846 C CA  . SER A 1 208 ? 5.83667   22.59329 -15.30668 1.000 24.66741  ? 208 SER A CA  1 
ATOM   1847 C C   . SER A 1 208 ? 6.34260   23.98266 -14.95060 1.000 26.40328  ? 208 SER A C   1 
ATOM   1848 O O   . SER A 1 208 ? 7.38165   24.41332 -15.46490 1.000 27.02220  ? 208 SER A O   1 
ATOM   1849 C CB  . SER A 1 208 ? 4.73020   22.69049 -16.36427 1.000 25.07705  ? 208 SER A CB  1 
ATOM   1850 O OG  . SER A 1 208 ? 4.17145   21.41037 -16.64216 1.000 29.10470  ? 208 SER A OG  1 
ATOM   1851 N N   . VAL A 1 209 ? 5.63931   24.69859 -14.06095 1.000 25.94342  ? 209 VAL A N   1 
ATOM   1852 C CA  . VAL A 1 209 ? 6.10249   26.03635 -13.70354 1.000 25.09610  ? 209 VAL A CA  1 
ATOM   1853 C C   . VAL A 1 209 ? 7.46699   25.96334 -13.02969 1.000 26.39551  ? 209 VAL A C   1 
ATOM   1854 O O   . VAL A 1 209 ? 8.34123   26.80408 -13.27412 1.000 27.63490  ? 209 VAL A O   1 
ATOM   1855 C CB  . VAL A 1 209 ? 5.07764   26.75872 -12.81119 1.000 25.66680  ? 209 VAL A CB  1 
ATOM   1856 C CG1 . VAL A 1 209 ? 5.64591   28.12172 -12.37879 1.000 26.82233  ? 209 VAL A CG1 1 
ATOM   1857 C CG2 . VAL A 1 209 ? 3.75271   26.93541 -13.55532 1.000 29.24239  ? 209 VAL A CG2 1 
ATOM   1858 N N   . GLY A 1 210 ? 7.68188   24.95186 -12.17303 1.000 23.55413  ? 210 GLY A N   1 
ATOM   1859 C CA  . GLY A 1 210 ? 8.99891   24.79716 -11.56152 1.000 24.13506  ? 210 GLY A CA  1 
ATOM   1860 C C   . GLY A 1 210 ? 10.09240  24.56873 -12.59025 1.000 26.62102  ? 210 GLY A C   1 
ATOM   1861 O O   . GLY A 1 210 ? 11.18674  25.14002 -12.48416 1.000 27.49588  ? 210 GLY A O   1 
ATOM   1862 N N   . CYS A 1 211 ? 9.81233   23.73963 -13.60289 1.000 25.00286  ? 211 CYS A N   1 
ATOM   1863 C CA  . CYS A 1 211 ? 10.78340  23.51166 -14.67170 1.000 25.91503  ? 211 CYS A CA  1 
ATOM   1864 C C   . CYS A 1 211 ? 11.07657  24.79050 -15.44634 1.000 28.86802  ? 211 CYS A C   1 
ATOM   1865 O O   . CYS A 1 211 ? 12.23111  25.04761 -15.83310 1.000 26.68099  ? 211 CYS A O   1 
ATOM   1866 C CB  . CYS A 1 211 ? 10.29989  22.40657 -15.62650 1.000 26.62533  ? 211 CYS A CB  1 
ATOM   1867 S SG  . CYS A 1 211 ? 10.10750  20.81223 -14.87665 1.000 26.91461  ? 211 CYS A SG  1 
ATOM   1868 N N   . ILE A 1 212 ? 10.04480  25.59443 -15.69422 1.000 25.62843  ? 212 ILE A N   1 
ATOM   1869 C CA  . ILE A 1 212 ? 10.22264  26.84176 -16.42318 1.000 26.31316  ? 212 ILE A CA  1 
ATOM   1870 C C   . ILE A 1 212 ? 11.00602  27.84969 -15.58974 1.000 27.59944  ? 212 ILE A C   1 
ATOM   1871 O O   . ILE A 1 212 ? 11.93772  28.49144 -16.09330 1.000 29.42284  ? 212 ILE A O   1 
ATOM   1872 C CB  . ILE A 1 212 ? 8.84651   27.39069 -16.85250 1.000 23.02484  ? 212 ILE A CB  1 
ATOM   1873 C CG1 . ILE A 1 212 ? 8.22989   26.45731 -17.90941 1.000 24.60343  ? 212 ILE A CG1 1 
ATOM   1874 C CG2 . ILE A 1 212 ? 8.93973   28.83304 -17.35019 1.000 26.38515  ? 212 ILE A CG2 1 
ATOM   1875 C CD1 . ILE A 1 212 ? 6.71383   26.60701 -18.06904 1.000 27.68949  ? 212 ILE A CD1 1 
ATOM   1876 N N   . MET A 1 213 ? 10.61218  28.03688 -14.32187 1.000 27.21575  ? 213 MET A N   1 
ATOM   1877 C CA  . MET A 1 213 ? 11.36979  28.86111 -13.37306 1.000 26.27115  ? 213 MET A CA  1 
ATOM   1878 C C   . MET A 1 213 ? 12.85402  28.52692 -13.35995 1.000 23.11088  ? 213 MET A C   1 
ATOM   1879 O O   . MET A 1 213 ? 13.71466  29.40999 -13.44552 1.000 27.31802  ? 213 MET A O   1 
ATOM   1880 C CB  . MET A 1 213 ? 10.90395  28.63523 -11.93744 1.000 27.29323  ? 213 MET A CB  1 
ATOM   1881 C CG  . MET A 1 213 ? 11.40850  29.70761 -11.01309 1.000 29.03873  ? 213 MET A CG  1 
ATOM   1882 S SD  . MET A 1 213 ? 10.39290  30.04370 -9.58941  1.000 30.97624  ? 213 MET A SD  1 
ATOM   1883 C CE  . MET A 1 213 ? 11.70886  30.46148 -8.43274  1.000 32.76649  ? 213 MET A CE  1 
ATOM   1884 N N   . ALA A 1 214 ? 13.15792  27.25310 -13.16059 1.000 27.64870  ? 214 ALA A N   1 
ATOM   1885 C CA  . ALA A 1 214 ? 14.54802  26.82693 -13.10152 1.000 26.79837  ? 214 ALA A CA  1 
ATOM   1886 C C   . ALA A 1 214 ? 15.29982  27.24338 -14.36475 1.000 30.00105  ? 214 ALA A C   1 
ATOM   1887 O O   . ALA A 1 214 ? 16.40558  27.79988 -14.30428 1.000 30.80556  ? 214 ALA A O   1 
ATOM   1888 C CB  . ALA A 1 214 ? 14.58817  25.30959 -12.91892 1.000 26.25947  ? 214 ALA A CB  1 
ATOM   1889 N N   . GLU A 1 215 ? 14.69923  26.97352 -15.52263 1.000 28.86852  ? 215 GLU A N   1 
ATOM   1890 C CA  . GLU A 1 215 ? 15.30203  27.32664 -16.80127 1.000 30.25178  ? 215 GLU A CA  1 
ATOM   1891 C C   . GLU A 1 215 ? 15.49380  28.83384 -16.96352 1.000 30.58302  ? 215 GLU A C   1 
ATOM   1892 O O   . GLU A 1 215 ? 16.49498  29.27067 -17.55199 1.000 31.87717  ? 215 GLU A O   1 
ATOM   1893 C CB  . GLU A 1 215 ? 14.44970  26.75236 -17.93329 1.000 28.54284  ? 215 GLU A CB  1 
ATOM   1894 C CG  . GLU A 1 215 ? 15.08516  26.87733 -19.29719 1.000 29.32602  ? 215 GLU A CG  1 
ATOM   1895 C CD  . GLU A 1 215 ? 14.40654  26.01383 -20.33995 1.000 29.88364  ? 215 GLU A CD  1 
ATOM   1896 O OE1 . GLU A 1 215 ? 13.74616  25.01894 -19.96289 1.000 30.79955  ? 215 GLU A OE1 1 
ATOM   1897 O OE2 . GLU A 1 215 ? 14.56468  26.30918 -21.54594 1.000 35.77218  ? 215 GLU A OE2 1 
ATOM   1898 N N   . LEU A 1 216 ? 14.54408  29.64825 -16.46556 1.000 28.45392  ? 216 LEU A N   1 
ATOM   1899 C CA  . LEU A 1 216 ? 14.73846  31.10233 -16.48771 1.000 27.61591  ? 216 LEU A CA  1 
ATOM   1900 C C   . LEU A 1 216 ? 15.92877  31.50443 -15.61709 1.000 28.36360  ? 216 LEU A C   1 
ATOM   1901 O O   . LEU A 1 216 ? 16.66797  32.44881 -15.94143 1.000 32.86379  ? 216 LEU A O   1 
ATOM   1902 C CB  . LEU A 1 216 ? 13.47880  31.80973 -15.99316 1.000 30.75765  ? 216 LEU A CB  1 
ATOM   1903 C CG  . LEU A 1 216 ? 12.30747  31.76190 -16.96987 1.000 33.46016  ? 216 LEU A CG  1 
ATOM   1904 C CD1 . LEU A 1 216 ? 11.14559  32.55275 -16.42876 1.000 32.21650  ? 216 LEU A CD1 1 
ATOM   1905 C CD2 . LEU A 1 216 ? 12.72405  32.32289 -18.31444 1.000 35.99309  ? 216 LEU A CD2 1 
ATOM   1906 N N   . LEU A 1 217 ? 16.12835  30.80342 -14.49886 1.000 27.25067  ? 217 LEU A N   1 
ATOM   1907 C CA  . LEU A 1 217 ? 17.21792  31.17129 -13.59519 1.000 29.24882  ? 217 LEU A CA  1 
ATOM   1908 C C   . LEU A 1 217 ? 18.58445  30.76699 -14.12507 1.000 30.03801  ? 217 LEU A C   1 
ATOM   1909 O O   . LEU A 1 217 ? 19.55359  31.50596 -13.94136 1.000 34.74034  ? 217 LEU A O   1 
ATOM   1910 C CB  . LEU A 1 217 ? 16.99428  30.55020 -12.21630 1.000 32.84342  ? 217 LEU A CB  1 
ATOM   1911 C CG  . LEU A 1 217 ? 15.80817  31.09732 -11.43078 1.000 33.41024  ? 217 LEU A CG  1 
ATOM   1912 C CD1 . LEU A 1 217 ? 15.51974  30.24259 -10.20416 1.000 36.29847  ? 217 LEU A CD1 1 
ATOM   1913 C CD2 . LEU A 1 217 ? 16.14340  32.53575 -11.01442 1.000 37.63437  ? 217 LEU A CD2 1 
ATOM   1914 N N   . THR A 1 218 ? 18.69840  29.58561 -14.73851 1.000 29.51540  ? 218 THR A N   1 
ATOM   1915 C CA  . THR A 1 218 ? 19.98898  29.03388 -15.12688 1.000 29.93804  ? 218 THR A CA  1 
ATOM   1916 C C   . THR A 1 218 ? 20.29861  29.20617 -16.60352 1.000 32.32193  ? 218 THR A C   1 
ATOM   1917 O O   . THR A 1 218 ? 21.47184  29.09393 -16.99389 1.000 31.23977  ? 218 THR A O   1 
ATOM   1918 C CB  . THR A 1 218 ? 20.04502  27.53614 -14.82786 1.000 29.18690  ? 218 THR A CB  1 
ATOM   1919 O OG1 . THR A 1 218 ? 19.12481  26.87797 -15.69362 1.000 29.75967  ? 218 THR A OG1 1 
ATOM   1920 C CG2 . THR A 1 218 ? 19.67840  27.23295 -13.36346 1.000 29.96725  ? 218 THR A CG2 1 
ATOM   1921 N N   . GLY A 1 219 ? 19.28352  29.45674 -17.42738 1.000 29.80333  ? 219 GLY A N   1 
ATOM   1922 C CA  . GLY A 1 219 ? 19.46269  29.45267 -18.86104 1.000 28.44233  ? 219 GLY A CA  1 
ATOM   1923 C C   . GLY A 1 219 ? 19.53754  28.07687 -19.47834 1.000 30.47822  ? 219 GLY A C   1 
ATOM   1924 O O   . GLY A 1 219 ? 19.88339  27.97138 -20.65820 1.000 34.37207  ? 219 GLY A O   1 
ATOM   1925 N N   . ARG A 1 220 ? 19.21046  27.02278 -18.72710 1.000 29.30282  ? 220 ARG A N   1 
ATOM   1926 C CA  . ARG A 1 220 ? 19.33924  25.64285 -19.18462 1.000 29.23440  ? 220 ARG A CA  1 
ATOM   1927 C C   . ARG A 1 220 ? 18.09340  24.83992 -18.83715 1.000 28.82727  ? 220 ARG A C   1 
ATOM   1928 O O   . ARG A 1 220 ? 17.48334  25.05079 -17.78881 1.000 27.98018  ? 220 ARG A O   1 
ATOM   1929 C CB  . ARG A 1 220 ? 20.55144  24.93991 -18.55111 1.000 30.24230  ? 220 ARG A CB  1 
ATOM   1930 C CG  . ARG A 1 220 ? 21.88552  25.66724 -18.70009 1.000 30.36594  ? 220 ARG A CG  1 
ATOM   1931 C CD  . ARG A 1 220 ? 22.33298  25.71246 -20.14771 1.000 31.02990  ? 220 ARG A CD  1 
ATOM   1932 N NE  . ARG A 1 220 ? 23.42972  26.65755 -20.34244 1.000 32.98795  ? 220 ARG A NE  1 
ATOM   1933 C CZ  . ARG A 1 220 ? 23.91811  27.02240 -21.52306 1.000 35.64979  ? 220 ARG A CZ  1 
ATOM   1934 N NH1 . ARG A 1 220 ? 23.40557  26.56429 -22.65433 1.000 40.37434  ? 220 ARG A NH1 1 
ATOM   1935 N NH2 . ARG A 1 220 ? 24.93767  27.88734 -21.57199 1.000 37.40347  ? 220 ARG A NH2 1 
ATOM   1936 N N   . THR A 1 221 ? 17.75138  23.88114 -19.70267 1.000 28.80215  ? 221 THR A N   1 
ATOM   1937 C CA  . THR A 1 221 ? 16.67647  22.94210 -19.39602 1.000 28.05993  ? 221 THR A CA  1 
ATOM   1938 C C   . THR A 1 221 ? 16.97245  22.20018 -18.10018 1.000 24.49665  ? 221 THR A C   1 
ATOM   1939 O O   . THR A 1 221 ? 18.09388  21.71580 -17.88705 1.000 26.91229  ? 221 THR A O   1 
ATOM   1940 C CB  . THR A 1 221 ? 16.50959  21.90949 -20.51292 1.000 31.95595  ? 221 THR A CB  1 
ATOM   1941 O OG1 . THR A 1 221 ? 16.66622  22.53946 -21.79107 1.000 35.18164  ? 221 THR A OG1 1 
ATOM   1942 C CG2 . THR A 1 221 ? 15.13656  21.24079 -20.41330 1.000 29.49901  ? 221 THR A CG2 1 
ATOM   1943 N N   . LEU A 1 222 ? 15.94795  22.07146 -17.25277 1.000 25.52686  ? 222 LEU A N   1 
ATOM   1944 C CA  . LEU A 1 222 ? 16.14993  21.42484 -15.95543 1.000 23.76032  ? 222 LEU A CA  1 
ATOM   1945 C C   . LEU A 1 222 ? 16.31613  19.91849 -16.11850 1.000 24.19111  ? 222 LEU A C   1 
ATOM   1946 O O   . LEU A 1 222 ? 17.25611  19.31873 -15.55849 1.000 25.25668  ? 222 LEU A O   1 
ATOM   1947 C CB  . LEU A 1 222 ? 14.98093  21.73967 -15.02156 1.000 28.33559  ? 222 LEU A CB  1 
ATOM   1948 C CG  . LEU A 1 222 ? 15.07507  21.16704 -13.59455 1.000 23.09292  ? 222 LEU A CG  1 
ATOM   1949 C CD1 . LEU A 1 222 ? 16.38965  21.64137 -12.92770 1.000 25.48647  ? 222 LEU A CD1 1 
ATOM   1950 C CD2 . LEU A 1 222 ? 13.87090  21.56841 -12.70418 1.000 23.56109  ? 222 LEU A CD2 1 
ATOM   1951 N N   . PHE A 1 223 ? 15.42923  19.29358 -16.89635 1.000 25.32383  ? 223 PHE A N   1 
ATOM   1952 C CA  . PHE A 1 223 ? 15.39557  17.83806 -17.05242 1.000 25.69279  ? 223 PHE A CA  1 
ATOM   1953 C C   . PHE A 1 223 ? 15.40966  17.47354 -18.53653 1.000 28.06309  ? 223 PHE A C   1 
ATOM   1954 O O   . PHE A 1 223 ? 14.40989  16.98802 -19.07779 1.000 27.71985  ? 223 PHE A O   1 
ATOM   1955 C CB  . PHE A 1 223 ? 14.15271  17.23427 -16.38967 1.000 25.42398  ? 223 PHE A CB  1 
ATOM   1956 C CG  . PHE A 1 223 ? 13.98490  17.55217 -14.91633 1.000 25.20508  ? 223 PHE A CG  1 
ATOM   1957 C CD1 . PHE A 1 223 ? 14.95506  17.16472 -13.97651 1.000 26.08649  ? 223 PHE A CD1 1 
ATOM   1958 C CD2 . PHE A 1 223 ? 12.84294  18.19764 -14.46109 1.000 22.24496  ? 223 PHE A CD2 1 
ATOM   1959 C CE1 . PHE A 1 223 ? 14.80500  17.43004 -12.61680 1.000 25.15483  ? 223 PHE A CE1 1 
ATOM   1960 C CE2 . PHE A 1 223 ? 12.68101  18.47640 -13.06895 1.000 22.27551  ? 223 PHE A CE2 1 
ATOM   1961 C CZ  . PHE A 1 223 ? 13.66773  18.08664 -12.15284 1.000 24.00533  ? 223 PHE A CZ  1 
ATOM   1962 N N   . PRO A 1 224 ? 16.53258  17.68731 -19.22940 1.000 26.33582  ? 224 PRO A N   1 
ATOM   1963 C CA  . PRO A 1 224 ? 16.57028  17.39210 -20.68338 1.000 27.40459  ? 224 PRO A CA  1 
ATOM   1964 C C   . PRO A 1 224 ? 16.81911  15.91595 -20.97329 1.000 27.14939  ? 224 PRO A C   1 
ATOM   1965 O O   . PRO A 1 224 ? 17.86198  15.49517 -21.48712 1.000 29.61246  ? 224 PRO A O   1 
ATOM   1966 C CB  . PRO A 1 224 ? 17.70895  18.28907 -21.16932 1.000 28.71513  ? 224 PRO A CB  1 
ATOM   1967 C CG  . PRO A 1 224 ? 18.65833  18.34106 -19.97473 1.000 28.20268  ? 224 PRO A CG  1 
ATOM   1968 C CD  . PRO A 1 224 ? 17.77649  18.31686 -18.74395 1.000 26.11322  ? 224 PRO A CD  1 
ATOM   1969 N N   . GLY A 1 225 ? 15.83425  15.09208 -20.64169 1.000 27.33180  ? 225 GLY A N   1 
ATOM   1970 C CA  . GLY A 1 225 ? 15.99126  13.66037 -20.81199 1.000 26.35663  ? 225 GLY A CA  1 
ATOM   1971 C C   . GLY A 1 225 ? 16.03561  13.27033 -22.28032 1.000 29.79401  ? 225 GLY A C   1 
ATOM   1972 O O   . GLY A 1 225 ? 15.36790  13.86675 -23.12814 1.000 29.31562  ? 225 GLY A O   1 
ATOM   1973 N N   . THR A 1 226 ? 16.84889  12.25091 -22.58878 1.000 27.49297  ? 226 THR A N   1 
ATOM   1974 C CA  . THR A 1 226 ? 16.90652  11.72511 -23.94949 1.000 28.70646  ? 226 THR A CA  1 
ATOM   1975 C C   . THR A 1 226 ? 15.75615  10.77940 -24.26186 1.000 29.23699  ? 226 THR A C   1 
ATOM   1976 O O   . THR A 1 226 ? 15.61961  10.34521 -25.41423 1.000 30.89028  ? 226 THR A O   1 
ATOM   1977 C CB  . THR A 1 226 ? 18.21384  10.96758 -24.18471 1.000 36.39767  ? 226 THR A CB  1 
ATOM   1978 O OG1 . THR A 1 226 ? 18.31674  9.92644  -23.20588 1.000 35.51007  ? 226 THR A OG1 1 
ATOM   1979 C CG2 . THR A 1 226 ? 19.41046  11.91120 -24.05097 1.000 35.83947  ? 226 THR A CG2 1 
ATOM   1980 N N   . ASP A 1 227 ? 14.96245  10.42996 -23.26438 1.000 29.32048  ? 227 ASP A N   1 
ATOM   1981 C CA  . ASP A 1 227 ? 13.78214  9.58841  -23.39973 1.000 28.09959  ? 227 ASP A CA  1 
ATOM   1982 C C   . ASP A 1 227 ? 13.10796  9.55842  -22.02561 1.000 28.86232  ? 227 ASP A C   1 
ATOM   1983 O O   . ASP A 1 227 ? 13.61697  10.12812 -21.05268 1.000 29.51616  ? 227 ASP A O   1 
ATOM   1984 C CB  . ASP A 1 227 ? 14.15650  8.18846  -23.89317 1.000 30.35336  ? 227 ASP A CB  1 
ATOM   1985 C CG  . ASP A 1 227 ? 15.18985  7.51499  -23.00691 1.000 37.35982  ? 227 ASP A CG  1 
ATOM   1986 O OD1 . ASP A 1 227 ? 14.83228  7.05702  -21.90353 1.000 32.30439  ? 227 ASP A OD1 1 
ATOM   1987 O OD2 . ASP A 1 227 ? 16.35810  7.40874  -23.43580 1.000 43.32240  ? 227 ASP A OD2 1 
ATOM   1988 N N   . HIS A 1 228 ? 11.95001  8.89497  -21.95502 1.000 29.14938  ? 228 HIS A N   1 
ATOM   1989 C CA  . HIS A 1 228 ? 11.15898  8.88205  -20.72590 1.000 27.41210  ? 228 HIS A CA  1 
ATOM   1990 C C   . HIS A 1 228 ? 11.98158  8.42237  -19.52350 1.000 30.63584  ? 228 HIS A C   1 
ATOM   1991 O O   . HIS A 1 228 ? 11.88174  8.99624  -18.42679 1.000 28.63775  ? 228 HIS A O   1 
ATOM   1992 C CB  . HIS A 1 228 ? 9.96008   7.94699  -20.88573 1.000 31.10668  ? 228 HIS A CB  1 
ATOM   1993 C CG  . HIS A 1 228 ? 8.91415   8.43021  -21.83605 1.000 32.63953  ? 228 HIS A CG  1 
ATOM   1994 N ND1 . HIS A 1 228 ? 9.16935   8.67997  -23.16691 1.000 35.45625  ? 228 HIS A ND1 1 
ATOM   1995 C CD2 . HIS A 1 228 ? 7.59345   8.67445  -21.65195 1.000 33.54496  ? 228 HIS A CD2 1 
ATOM   1996 C CE1 . HIS A 1 228 ? 8.05386   9.06859  -23.75912 1.000 37.67058  ? 228 HIS A CE1 1 
ATOM   1997 N NE2 . HIS A 1 228 ? 7.08125   9.06386  -22.86704 1.000 33.73778  ? 228 HIS A NE2 1 
ATOM   1998 N N   . ILE A 1 229 ? 12.73153  7.32722  -19.68823 1.000 29.09303  ? 229 ILE A N   1 
ATOM   1999 C CA  . ILE A 1 229 ? 13.41449  6.72589  -18.54549 1.000 30.17288  ? 229 ILE A CA  1 
ATOM   2000 C C   . ILE A 1 229 ? 14.63168  7.55450  -18.14348 1.000 29.22440  ? 229 ILE A C   1 
ATOM   2001 O O   . ILE A 1 229 ? 14.89943  7.75560  -16.95096 1.000 28.87212  ? 229 ILE A O   1 
ATOM   2002 C CB  . ILE A 1 229 ? 13.80083  5.26998  -18.86160 1.000 35.28204  ? 229 ILE A CB  1 
ATOM   2003 C CG1 . ILE A 1 229 ? 12.55749  4.37422  -18.99542 1.000 38.75427  ? 229 ILE A CG1 1 
ATOM   2004 C CG2 . ILE A 1 229 ? 14.73012  4.72978  -17.75740 1.000 35.12820  ? 229 ILE A CG2 1 
ATOM   2005 C CD1 . ILE A 1 229 ? 11.59788  4.39534  -17.78434 1.000 38.78868  ? 229 ILE A CD1 1 
ATOM   2006 N N   . ASP A 1 230 ? 15.39575  8.04185  -19.12364 1.000 29.85197  ? 230 ASP A N   1 
ATOM   2007 C CA  . ASP A 1 230 ? 16.48007  8.96854  -18.81260 1.000 25.55997  ? 230 ASP A CA  1 
ATOM   2008 C C   . ASP A 1 230 ? 15.95627  10.18708 -18.07822 1.000 24.38789  ? 230 ASP A C   1 
ATOM   2009 O O   . ASP A 1 230 ? 16.55153  10.63296 -17.08712 1.000 27.66367  ? 230 ASP A O   1 
ATOM   2010 C CB  . ASP A 1 230 ? 17.20414  9.38061  -20.10379 1.000 29.05457  ? 230 ASP A CB  1 
ATOM   2011 C CG  . ASP A 1 230 ? 18.40165  10.27865 -19.85590 1.000 31.98736  ? 230 ASP A CG  1 
ATOM   2012 O OD1 . ASP A 1 230 ? 19.34805  9.83348  -19.19345 1.000 32.56323  ? 230 ASP A OD1 1 
ATOM   2013 O OD2 . ASP A 1 230 ? 18.39592  11.43900 -20.33251 1.000 32.34458  ? 230 ASP A OD2 1 
ATOM   2014 N N   . GLN A 1 231 ? 14.82150  10.72542 -18.52793 1.000 24.61226  ? 231 GLN A N   1 
ATOM   2015 C CA  . GLN A 1 231 ? 14.28839  11.91197 -17.87072 1.000 24.40620  ? 231 GLN A CA  1 
ATOM   2016 C C   . GLN A 1 231 ? 13.86696  11.59782 -16.43859 1.000 25.31070  ? 231 GLN A C   1 
ATOM   2017 O O   . GLN A 1 231 ? 14.08337  12.40312 -15.51502 1.000 24.16323  ? 231 GLN A O   1 
ATOM   2018 C CB  . GLN A 1 231 ? 13.11713  12.47061 -18.67765 1.000 23.55987  ? 231 GLN A CB  1 
ATOM   2019 C CG  . GLN A 1 231 ? 12.59221  13.77384 -18.13429 1.000 23.81994  ? 231 GLN A CG  1 
ATOM   2020 C CD  . GLN A 1 231 ? 11.58958  14.43927 -19.05615 1.000 29.67567  ? 231 GLN A CD  1 
ATOM   2021 O OE1 . GLN A 1 231 ? 11.59292  14.23149 -20.28412 1.000 29.11491  ? 231 GLN A OE1 1 
ATOM   2022 N NE2 . GLN A 1 231 ? 10.67358  15.20420 -18.45772 1.000 30.22037  ? 231 GLN A NE2 1 
ATOM   2023 N N   . LEU A 1 232 ? 13.23661  10.44106 -16.22735 1.000 26.04911  ? 232 LEU A N   1 
ATOM   2024 C CA  . LEU A 1 232 ? 12.88837  10.06322 -14.86168 1.000 24.93173  ? 232 LEU A CA  1 
ATOM   2025 C C   . LEU A 1 232 ? 14.12650  10.00895 -13.97766 1.000 28.22376  ? 232 LEU A C   1 
ATOM   2026 O O   . LEU A 1 232 ? 14.09336  10.46385 -12.82696 1.000 26.81571  ? 232 LEU A O   1 
ATOM   2027 C CB  . LEU A 1 232 ? 12.15979  8.71722  -14.84609 1.000 28.29298  ? 232 LEU A CB  1 
ATOM   2028 C CG  . LEU A 1 232 ? 11.80586  8.25345  -13.42197 1.000 26.52194  ? 232 LEU A CG  1 
ATOM   2029 C CD1 . LEU A 1 232 ? 10.82381  9.17865  -12.67019 1.000 29.28896  ? 232 LEU A CD1 1 
ATOM   2030 C CD2 . LEU A 1 232 ? 11.33623  6.81884  -13.39766 1.000 29.80807  ? 232 LEU A CD2 1 
ATOM   2031 N N   . LYS A 1 233 ? 15.23138  9.45638  -14.50048 1.000 28.74611  ? 233 LYS A N   1 
ATOM   2032 C CA  . LYS A 1 233 ? 16.46455  9.38976  -13.71642 1.000 27.98549  ? 233 LYS A CA  1 
ATOM   2033 C C   . LYS A 1 233 ? 16.97702  10.77802 -13.36568 1.000 28.73282  ? 233 LYS A C   1 
ATOM   2034 O O   . LYS A 1 233 ? 17.43555  11.00530 -12.24079 1.000 31.18663  ? 233 LYS A O   1 
ATOM   2035 C CB  . LYS A 1 233 ? 17.53261  8.58503  -14.46045 1.000 30.65781  ? 233 LYS A CB  1 
ATOM   2036 C CG  . LYS A 1 233 ? 17.21596  7.08168  -14.51445 1.000 28.95504  ? 233 LYS A CG  1 
ATOM   2037 C CD  . LYS A 1 233 ? 18.20987  6.32082  -15.35251 1.000 31.44835  ? 233 LYS A CD  1 
ATOM   2038 C CE  . LYS A 1 233 ? 17.76423  4.88141  -15.56867 1.000 34.79801  ? 233 LYS A CE  1 
ATOM   2039 N NZ  . LYS A 1 233 ? 18.79152  4.15867  -16.38453 1.000 35.03743  ? 233 LYS A NZ  1 
ATOM   2040 N N   . LEU A 1 234 ? 16.90679  11.72475 -14.30909 1.000 26.16526  ? 234 LEU A N   1 
ATOM   2041 C CA  . LEU A 1 234 ? 17.31074  13.09809 -13.99635 1.000 24.83498  ? 234 LEU A CA  1 
ATOM   2042 C C   . LEU A 1 234 ? 16.43459  13.68095 -12.89445 1.000 28.79336  ? 234 LEU A C   1 
ATOM   2043 O O   . LEU A 1 234 ? 16.92836  14.37755 -11.98420 1.000 26.19337  ? 234 LEU A O   1 
ATOM   2044 C CB  . LEU A 1 234 ? 17.23442  13.96144 -15.25865 1.000 24.72923  ? 234 LEU A CB  1 
ATOM   2045 C CG  . LEU A 1 234 ? 18.15184  13.61306 -16.43996 1.000 25.59286  ? 234 LEU A CG  1 
ATOM   2046 C CD1 . LEU A 1 234 ? 17.86449  14.53767 -17.63144 1.000 29.12702  ? 234 LEU A CD1 1 
ATOM   2047 C CD2 . LEU A 1 234 ? 19.61884  13.69794 -16.04731 1.000 31.06927  ? 234 LEU A CD2 1 
ATOM   2048 N N   . ILE A 1 235 ? 15.12834  13.40824 -12.95399 1.000 24.17604  ? 235 ILE A N   1 
ATOM   2049 C CA  . ILE A 1 235 ? 14.21427  13.95399 -11.95155 1.000 26.98523  ? 235 ILE A CA  1 
ATOM   2050 C C   . ILE A 1 235 ? 14.52649  13.36394 -10.57222 1.000 24.89529  ? 235 ILE A C   1 
ATOM   2051 O O   . ILE A 1 235 ? 14.65584  14.08604 -9.57582  1.000 25.17176  ? 235 ILE A O   1 
ATOM   2052 C CB  . ILE A 1 235 ? 12.74657  13.69828 -12.35881 1.000 24.61119  ? 235 ILE A CB  1 
ATOM   2053 C CG1 . ILE A 1 235 ? 12.33398  14.60142 -13.53827 1.000 23.93368  ? 235 ILE A CG1 1 
ATOM   2054 C CG2 . ILE A 1 235 ? 11.80908  13.90035 -11.15814 1.000 24.63430  ? 235 ILE A CG2 1 
ATOM   2055 C CD1 . ILE A 1 235 ? 11.11391  14.14489 -14.27960 1.000 25.57779  ? 235 ILE A CD1 1 
ATOM   2056 N N   . LEU A 1 236 ? 14.66494  12.03825 -10.48936 1.000 25.99465  ? 236 LEU A N   1 
ATOM   2057 C CA  . LEU A 1 236 ? 14.82969  11.41511 -9.17328  1.000 25.70550  ? 236 LEU A CA  1 
ATOM   2058 C C   . LEU A 1 236 ? 16.19138  11.73142 -8.57294  1.000 29.98793  ? 236 LEU A C   1 
ATOM   2059 O O   . LEU A 1 236 ? 16.33787  11.76625 -7.33703  1.000 29.13824  ? 236 LEU A O   1 
ATOM   2060 C CB  . LEU A 1 236 ? 14.61586  9.89818  -9.26819  1.000 27.04062  ? 236 LEU A CB  1 
ATOM   2061 C CG  . LEU A 1 236 ? 13.22126  9.45144  -9.75310  1.000 29.46841  ? 236 LEU A CG  1 
ATOM   2062 C CD1 . LEU A 1 236 ? 13.12495  7.92347  -9.80465  1.000 31.98955  ? 236 LEU A CD1 1 
ATOM   2063 C CD2 . LEU A 1 236 ? 12.11967  10.05429 -8.90273  1.000 30.00530  ? 236 LEU A CD2 1 
ATOM   2064 N N   . ARG A 1 237 ? 17.19706  11.97352 -9.41531  1.000 27.14139  ? 237 ARG A N   1 
ATOM   2065 C CA  . ARG A 1 237 ? 18.47376  12.44329 -8.88467  1.000 26.69716  ? 237 ARG A CA  1 
ATOM   2066 C C   . ARG A 1 237 ? 18.32090  13.76561 -8.13749  1.000 30.84133  ? 237 ARG A C   1 
ATOM   2067 O O   . ARG A 1 237 ? 18.95851  13.97073 -7.09714  1.000 29.92567  ? 237 ARG A O   1 
ATOM   2068 C CB  . ARG A 1 237 ? 19.50059  12.57718 -10.00305 1.000 29.71773  ? 237 ARG A CB  1 
ATOM   2069 C CG  . ARG A 1 237 ? 20.92866  12.76288 -9.46599  1.000 39.69291  ? 237 ARG A CG  1 
ATOM   2070 C CD  . ARG A 1 237 ? 21.94296  12.62246 -10.57702 1.000 57.82840  ? 237 ARG A CD  1 
ATOM   2071 N NE  . ARG A 1 237 ? 22.07438  13.87159 -11.31392 1.000 69.50836  ? 237 ARG A NE  1 
ATOM   2072 C CZ  . ARG A 1 237 ? 22.00297  13.96850 -12.63508 1.000 71.07775  ? 237 ARG A CZ  1 
ATOM   2073 N NH1 . ARG A 1 237 ? 21.88411  12.89593 -13.40258 1.000 77.33410  ? 237 ARG A NH1 1 
ATOM   2074 N NH2 . ARG A 1 237 ? 22.04378  15.17061 -13.19954 1.000 65.89958  ? 237 ARG A NH2 1 
ATOM   2075 N N   . LEU A 1 238 ? 17.48429  14.67493 -8.64748  1.000 26.50174  ? 238 LEU A N   1 
ATOM   2076 C CA  . LEU A 1 238 ? 17.31564  15.97068 -7.98869  1.000 26.31828  ? 238 LEU A CA  1 
ATOM   2077 C C   . LEU A 1 238 ? 16.40858  15.87310 -6.77162  1.000 26.90952  ? 238 LEU A C   1 
ATOM   2078 O O   . LEU A 1 238 ? 16.76274  16.35410 -5.68601  1.000 28.14741  ? 238 LEU A O   1 
ATOM   2079 C CB  . LEU A 1 238 ? 16.75876  17.01720 -8.96340  1.000 28.38454  ? 238 LEU A CB  1 
ATOM   2080 C CG  . LEU A 1 238 ? 16.49380  18.38601 -8.30568  1.000 26.13566  ? 238 LEU A CG  1 
ATOM   2081 C CD1 . LEU A 1 238 ? 17.80923  19.11392 -7.93058  1.000 27.30984  ? 238 LEU A CD1 1 
ATOM   2082 C CD2 . LEU A 1 238 ? 15.61741  19.23998 -9.21499  1.000 28.08868  ? 238 LEU A CD2 1 
ATOM   2083 N N   . VAL A 1 239 ? 15.23721  15.24415 -6.91931  1.000 26.03900  ? 239 VAL A N   1 
ATOM   2084 C CA  . VAL A 1 239 ? 14.22741  15.29847 -5.85853  1.000 27.47018  ? 239 VAL A CA  1 
ATOM   2085 C C   . VAL A 1 239 ? 14.23592  14.08286 -4.94060  1.000 28.48621  ? 239 VAL A C   1 
ATOM   2086 O O   . VAL A 1 239 ? 13.52338  14.08805 -3.92348  1.000 31.70336  ? 239 VAL A O   1 
ATOM   2087 C CB  . VAL A 1 239 ? 12.81060  15.51825 -6.44489  1.000 25.93702  ? 239 VAL A CB  1 
ATOM   2088 C CG1 . VAL A 1 239 ? 12.83745  16.69401 -7.39621  1.000 26.56594  ? 239 VAL A CG1 1 
ATOM   2089 C CG2 . VAL A 1 239 ? 12.28055  14.25772 -7.20307  1.000 26.63676  ? 239 VAL A CG2 1 
ATOM   2090 N N   . GLY A 1 240 ? 15.02456  13.06270 -5.24367  1.000 27.99704  ? 240 GLY A N   1 
ATOM   2091 C CA  . GLY A 1 240 ? 15.06178  11.84814 -4.45385  1.000 28.89545  ? 240 GLY A CA  1 
ATOM   2092 C C   . GLY A 1 240 ? 14.07116  10.80944 -4.94955  1.000 29.24062  ? 240 GLY A C   1 
ATOM   2093 O O   . GLY A 1 240 ? 13.06121  11.11717 -5.57220  1.000 30.40512  ? 240 GLY A O   1 
ATOM   2094 N N   . THR A 1 241 ? 14.39236  9.54344  -4.68902  1.000 29.36982  ? 241 THR A N   1 
ATOM   2095 C CA  . THR A 1 241 ? 13.47888  8.47625  -5.05192  1.000 28.14994  ? 241 THR A CA  1 
ATOM   2096 C C   . THR A 1 241 ? 12.24857  8.49703  -4.13362  1.000 30.85224  ? 241 THR A C   1 
ATOM   2097 O O   . THR A 1 241 ? 12.29802  9.03084  -3.02309  1.000 35.04227  ? 241 THR A O   1 
ATOM   2098 C CB  . THR A 1 241 ? 14.18955  7.12211  -4.98335  1.000 28.99336  ? 241 THR A CB  1 
ATOM   2099 O OG1 . THR A 1 241 ? 14.97021  7.05451  -3.78537  1.000 32.20971  ? 241 THR A OG1 1 
ATOM   2100 C CG2 . THR A 1 241 ? 15.12467  6.95082  -6.17922  1.000 31.57930  ? 241 THR A CG2 1 
ATOM   2101 N N   . PRO A 1 242 ? 11.11904  7.95795  -4.59338  1.000 30.26573  ? 242 PRO A N   1 
ATOM   2102 C CA  . PRO A 1 242 ? 9.89689   8.00203  -3.78275  1.000 36.39333  ? 242 PRO A CA  1 
ATOM   2103 C C   . PRO A 1 242 ? 10.00634  7.15214  -2.53431  1.000 36.24583  ? 242 PRO A C   1 
ATOM   2104 O O   . PRO A 1 242 ? 10.62946  6.09053  -2.53165  1.000 35.08052  ? 242 PRO A O   1 
ATOM   2105 C CB  . PRO A 1 242 ? 8.81484   7.43217  -4.71131  1.000 34.16363  ? 242 PRO A CB  1 
ATOM   2106 C CG  . PRO A 1 242 ? 9.45100   7.25118  -6.02410  1.000 36.28656  ? 242 PRO A CG  1 
ATOM   2107 C CD  . PRO A 1 242 ? 10.92583  7.21158  -5.84187  1.000 34.31647  ? 242 PRO A CD  1 
ATOM   2108 N N   . GLY A 1 243 ? 9.33786   7.63044  -1.46042  1.000 40.07387  ? 243 GLY A N   1 
ATOM   2109 C CA  . GLY A 1 243 ? 9.12459   6.81868  -0.28348  1.000 40.48484  ? 243 GLY A CA  1 
ATOM   2110 C C   . GLY A 1 243 ? 7.86589   5.96700  -0.39412  1.000 44.84671  ? 243 GLY A C   1 
ATOM   2111 O O   . GLY A 1 243 ? 7.11481   6.04671  -1.36587  1.000 39.83464  ? 243 GLY A O   1 
ATOM   2112 N N   . ALA A 1 244 ? 7.65309   5.13500  0.63202   1.000 46.30780  ? 244 ALA A N   1 
ATOM   2113 C CA  . ALA A 1 244 ? 6.56200   4.16479  0.59864   1.000 46.89438  ? 244 ALA A CA  1 
ATOM   2114 C C   . ALA A 1 244 ? 5.20896   4.84635  0.46501   1.000 47.52265  ? 244 ALA A C   1 
ATOM   2115 O O   . ALA A 1 244 ? 4.29098   4.30776  -0.16597  1.000 47.67777  ? 244 ALA A O   1 
ATOM   2116 C CB  . ALA A 1 244 ? 6.59865   3.29952  1.85503   1.000 51.03932  ? 244 ALA A CB  1 
ATOM   2117 N N   . GLU A 1 245 ? 5.07074   6.03190  1.04380   1.000 42.60150  ? 245 GLU A N   1 
ATOM   2118 C CA  . GLU A 1 245 ? 3.78978   6.71564  1.02410   1.000 46.71421  ? 245 GLU A CA  1 
ATOM   2119 C C   . GLU A 1 245 ? 3.41063   7.11558  -0.39745  1.000 41.44189  ? 245 GLU A C   1 
ATOM   2120 O O   . GLU A 1 245 ? 2.25905   6.93784  -0.81782  1.000 43.13276  ? 245 GLU A O   1 
ATOM   2121 C CB  . GLU A 1 245 ? 3.87862   7.89696  1.99115   1.000 53.91210  ? 245 GLU A CB  1 
ATOM   2122 C CG  . GLU A 1 245 ? 2.66354   8.75899  2.18122   1.000 61.00862  ? 245 GLU A CG  1 
ATOM   2123 C CD  . GLU A 1 245 ? 3.01744   10.05104 2.92628   1.000 68.48354  ? 245 GLU A CD  1 
ATOM   2124 O OE1 . GLU A 1 245 ? 4.05480   10.05956 3.63313   1.000 69.50215  ? 245 GLU A OE1 1 
ATOM   2125 O OE2 . GLU A 1 245 ? 2.26392   11.04391 2.82386   1.000 69.75458  ? 245 GLU A OE2 1 
ATOM   2126 N N   . LEU A 1 246 ? 4.37073   7.60298  -1.17771  1.000 37.08808  ? 246 LEU A N   1 
ATOM   2127 C CA  . LEU A 1 246 ? 4.03729   7.93314  -2.55531  1.000 36.82281  ? 246 LEU A CA  1 
ATOM   2128 C C   . LEU A 1 246 ? 3.90792   6.66357  -3.38861  1.000 36.62212  ? 246 LEU A C   1 
ATOM   2129 O O   . LEU A 1 246 ? 3.03197   6.57296  -4.25353  1.000 38.69711  ? 246 LEU A O   1 
ATOM   2130 C CB  . LEU A 1 246 ? 5.08107   8.87585  -3.14915  1.000 36.79251  ? 246 LEU A CB  1 
ATOM   2131 C CG  . LEU A 1 246 ? 4.93340   9.16072  -4.65140  1.000 34.11333  ? 246 LEU A CG  1 
ATOM   2132 C CD1 . LEU A 1 246 ? 3.54440   9.77195  -4.94746  1.000 34.11919  ? 246 LEU A CD1 1 
ATOM   2133 C CD2 . LEU A 1 246 ? 6.01724   10.07469 -5.12591  1.000 39.02838  ? 246 LEU A CD2 1 
ATOM   2134 N N   . LEU A 1 247 ? 4.74747   5.65805  -3.11900  1.000 36.49131  ? 247 LEU A N   1 
ATOM   2135 C CA  . LEU A 1 247 ? 4.64343   4.38760  -3.84002  1.000 37.98184  ? 247 LEU A CA  1 
ATOM   2136 C C   . LEU A 1 247 ? 3.22369   3.83673  -3.78326  1.000 38.93893  ? 247 LEU A C   1 
ATOM   2137 O O   . LEU A 1 247 ? 2.68727   3.35876  -4.79085  1.000 43.07575  ? 247 LEU A O   1 
ATOM   2138 C CB  . LEU A 1 247 ? 5.60877   3.36282  -3.25355  1.000 44.03430  ? 247 LEU A CB  1 
ATOM   2139 C CG  . LEU A 1 247 ? 6.99061   3.27026  -3.88052  1.000 48.52127  ? 247 LEU A CG  1 
ATOM   2140 C CD1 . LEU A 1 247 ? 7.81914   2.24526  -3.11145  1.000 51.24380  ? 247 LEU A CD1 1 
ATOM   2141 C CD2 . LEU A 1 247 ? 6.91191   2.93400  -5.36932  1.000 51.17146  ? 247 LEU A CD2 1 
ATOM   2142 N N   . LYS A 1 248 ? 2.61186   3.86763  -2.59234  1.000 40.99151  ? 248 LYS A N   1 
ATOM   2143 C CA  . LYS A 1 248 ? 1.24076   3.38956  -2.44039  1.000 41.95956  ? 248 LYS A CA  1 
ATOM   2144 C C   . LYS A 1 248 ? 0.29175   4.03214  -3.43514  1.000 41.17961  ? 248 LYS A C   1 
ATOM   2145 O O   . LYS A 1 248 ? -0.70201  3.41267  -3.83009  1.000 47.97976  ? 248 LYS A O   1 
ATOM   2146 C CB  . LYS A 1 248 ? 0.72611   3.66472  -1.02682  1.000 49.53117  ? 248 LYS A CB  1 
ATOM   2147 C CG  . LYS A 1 248 ? 0.75295   2.49040  -0.06266  1.000 61.04727  ? 248 LYS A CG  1 
ATOM   2148 C CD  . LYS A 1 248 ? 0.73676   2.97609  1.38619   1.000 66.17803  ? 248 LYS A CD  1 
ATOM   2149 C CE  . LYS A 1 248 ? 1.22217   1.89989  2.35627   1.000 69.97069  ? 248 LYS A CE  1 
ATOM   2150 N NZ  . LYS A 1 248 ? 2.55054   1.31958  1.99739   1.000 70.17986  ? 248 LYS A NZ  1 
ATOM   2151 N N   . LYS A 1 249 ? 0.53980   5.28155  -3.81161  1.000 40.64224  ? 249 LYS A N   1 
ATOM   2152 C CA  . LYS A 1 249 ? -0.39580  6.01365  -4.65489  1.000 40.82096  ? 249 LYS A CA  1 
ATOM   2153 C C   . LYS A 1 249 ? -0.18893  5.78627  -6.14386  1.000 43.68787  ? 249 LYS A C   1 
ATOM   2154 O O   . LYS A 1 249 ? -0.96650  6.32091  -6.94245  1.000 44.57916  ? 249 LYS A O   1 
ATOM   2155 C CB  . LYS A 1 249 ? -0.31541  7.51406  -4.36306  1.000 39.59303  ? 249 LYS A CB  1 
ATOM   2156 C CG  . LYS A 1 249 ? -0.33181  7.84123  -2.90127  1.000 43.52751  ? 249 LYS A CG  1 
ATOM   2157 C CD  . LYS A 1 249 ? -0.27000  9.34205  -2.70668  1.000 44.84112  ? 249 LYS A CD  1 
ATOM   2158 C CE  . LYS A 1 249 ? -0.06980  9.70887  -1.24801  1.000 42.59526  ? 249 LYS A CE  1 
ATOM   2159 N NZ  . LYS A 1 249 ? 0.02071   11.18694 -1.07906  1.000 39.15348  ? 249 LYS A NZ  1 
ATOM   2160 N N   . ILE A 1 250 ? 0.82720   5.02844  -6.53893  1.000 42.16054  ? 250 ILE A N   1 
ATOM   2161 C CA  . ILE A 1 250 ? 1.03623   4.68273  -7.93990  1.000 45.67557  ? 250 ILE A CA  1 
ATOM   2162 C C   . ILE A 1 250 ? 0.21446   3.43950  -8.25807  1.000 49.12135  ? 250 ILE A C   1 
ATOM   2163 O O   . ILE A 1 250 ? 0.47458   2.35831  -7.72017  1.000 49.02310  ? 250 ILE A O   1 
ATOM   2164 C CB  . ILE A 1 250 ? 2.52533   4.46614  -8.25169  1.000 44.29225  ? 250 ILE A CB  1 
ATOM   2165 C CG1 . ILE A 1 250 ? 3.28680   5.79194  -8.12918  1.000 39.58491  ? 250 ILE A CG1 1 
ATOM   2166 C CG2 . ILE A 1 250 ? 2.70699   3.86117  -9.64209  1.000 45.32042  ? 250 ILE A CG2 1 
ATOM   2167 C CD1 . ILE A 1 250 ? 4.79606   5.64606  -8.05161  1.000 38.15815  ? 250 ILE A CD1 1 
ATOM   2168 N N   . SER A 1 251 ? -0.76953  3.59241  -9.14888  1.000 52.13529  ? 251 SER A N   1 
ATOM   2169 C CA  . SER A 1 251 ? -1.74054  2.52509  -9.37947  1.000 58.17377  ? 251 SER A CA  1 
ATOM   2170 C C   . SER A 1 251 ? -1.14165  1.37201  -10.17401 1.000 63.04265  ? 251 SER A C   1 
ATOM   2171 O O   . SER A 1 251 ? -1.38881  0.20229  -9.85845  1.000 68.37469  ? 251 SER A O   1 
ATOM   2172 C CB  . SER A 1 251 ? -2.96802  3.08695  -10.09219 1.000 61.15101  ? 251 SER A CB  1 
ATOM   2173 O OG  . SER A 1 251 ? -3.35308  4.32948  -9.52735  1.000 60.62325  ? 251 SER A OG  1 
ATOM   2174 N N   A SER A 1 252 ? -0.35450  1.67370  -11.20488 0.540 60.33613  ? 252 SER A N   1 
ATOM   2175 N N   B SER A 1 252 ? -0.36321  1.67780  -11.21089 0.460 61.47986  ? 252 SER A N   1 
ATOM   2176 C CA  A SER A 1 252 ? 0.22758   0.62596  -12.03618 0.540 58.57625  ? 252 SER A CA  1 
ATOM   2177 C CA  B SER A 1 252 ? 0.25419   0.63723  -12.02349 0.460 60.52337  ? 252 SER A CA  1 
ATOM   2178 C C   A SER A 1 252 ? 1.21114   -0.22964 -11.24637 0.540 59.76104  ? 252 SER A C   1 
ATOM   2179 C C   B SER A 1 252 ? 1.20699   -0.21960 -11.20233 0.460 60.50620  ? 252 SER A C   1 
ATOM   2180 O O   A SER A 1 252 ? 2.31682   0.21972  -10.92374 0.540 59.61522  ? 252 SER A O   1 
ATOM   2181 O O   B SER A 1 252 ? 2.29035   0.23700  -10.82189 0.460 60.29316  ? 252 SER A O   1 
ATOM   2182 C CB  A SER A 1 252 ? 0.91697   1.23886  -13.25788 0.540 54.50694  ? 252 SER A CB  1 
ATOM   2183 C CB  B SER A 1 252 ? 1.00248   1.24926  -13.20899 0.460 58.65863  ? 252 SER A CB  1 
ATOM   2184 O OG  A SER A 1 252 ? 0.73973   2.64298  -13.27698 0.540 52.93280  ? 252 SER A OG  1 
ATOM   2185 O OG  B SER A 1 252 ? 1.68115   0.24263  -13.93604 0.460 57.77086  ? 252 SER A OG  1 
ATOM   2186 N N   . GLU A 1 253 ? 0.81957   -1.46677 -10.92949 1.000 59.11110  ? 253 GLU A N   1 
ATOM   2187 C CA  . GLU A 1 253 ? 1.74375   -2.37369 -10.26320 1.000 62.00567  ? 253 GLU A CA  1 
ATOM   2188 C C   . GLU A 1 253 ? 3.03316   -2.50198 -11.05143 1.000 60.38163  ? 253 GLU A C   1 
ATOM   2189 O O   . GLU A 1 253 ? 4.10131   -2.72336 -10.47259 1.000 60.90455  ? 253 GLU A O   1 
ATOM   2190 C CB  . GLU A 1 253 ? 1.11619   -3.75379 -10.07761 1.000 69.70607  ? 253 GLU A CB  1 
ATOM   2191 C CG  . GLU A 1 253 ? 2.14972   -4.85730 -9.86946  1.000 76.53017  ? 253 GLU A CG  1 
ATOM   2192 C CD  . GLU A 1 253 ? 1.52377   -6.22946 -9.68530  1.000 83.43963  ? 253 GLU A CD  1 
ATOM   2193 O OE1 . GLU A 1 253 ? 0.36859   -6.41781 -10.12288 1.000 85.13815  ? 253 GLU A OE1 1 
ATOM   2194 O OE2 . GLU A 1 253 ? 2.18779   -7.11942 -9.10644  1.000 85.14259  ? 253 GLU A OE2 1 
ATOM   2195 N N   . SER A 1 254 ? 2.95261   -2.37663 -12.37446 1.000 58.34859  ? 254 SER A N   1 
ATOM   2196 C CA  . SER A 1 254 ? 4.15219   -2.47484 -13.18860 1.000 57.72354  ? 254 SER A CA  1 
ATOM   2197 C C   . SER A 1 254 ? 5.00589   -1.21420 -13.07810 1.000 51.79404  ? 254 SER A C   1 
ATOM   2198 O O   . SER A 1 254 ? 6.23604   -1.30568 -13.04357 1.000 51.76862  ? 254 SER A O   1 
ATOM   2199 C CB  . SER A 1 254 ? 3.76340   -2.78755 -14.63843 1.000 62.61342  ? 254 SER A CB  1 
ATOM   2200 O OG  . SER A 1 254 ? 3.77417   -1.63635 -15.44622 1.000 67.29234  ? 254 SER A OG  1 
ATOM   2201 N N   . ALA A 1 255 ? 4.38346   -0.03604 -12.98659 1.000 52.27044  ? 255 ALA A N   1 
ATOM   2202 C CA  . ALA A 1 255 ? 5.15497   1.18719  -12.76287 1.000 47.36486  ? 255 ALA A CA  1 
ATOM   2203 C C   . ALA A 1 255 ? 5.77903   1.18697  -11.37033 1.000 48.28465  ? 255 ALA A C   1 
ATOM   2204 O O   . ALA A 1 255 ? 6.95766   1.53148  -11.20865 1.000 46.41064  ? 255 ALA A O   1 
ATOM   2205 C CB  . ALA A 1 255 ? 4.27755   2.41851  -12.97577 1.000 45.57033  ? 255 ALA A CB  1 
ATOM   2206 N N   A ARG A 1 256 ? 4.98570   0.87113  -10.34940 0.440 50.32173  ? 256 ARG A N   1 
ATOM   2207 N N   B ARG A 1 256 ? 5.02550   0.74374  -10.35797 0.560 47.21321  ? 256 ARG A N   1 
ATOM   2208 C CA  A ARG A 1 256 ? 5.59008   0.29514  -9.16500  0.440 51.06035  ? 256 ARG A CA  1 
ATOM   2209 C CA  B ARG A 1 256 ? 5.57205   0.64494  -9.00148  0.560 46.38438  ? 256 ARG A CA  1 
ATOM   2210 C C   A ARG A 1 256 ? 6.33573   -0.94296 -9.61600  0.440 52.96407  ? 256 ARG A C   1 
ATOM   2211 C C   B ARG A 1 256 ? 6.79320   -0.26236 -8.96190  0.560 41.14566  ? 256 ARG A C   1 
ATOM   2212 O O   A ARG A 1 256 ? 6.09085   -1.46797 -10.69687 0.440 57.88587  ? 256 ARG A O   1 
ATOM   2213 O O   B ARG A 1 256 ? 7.83730   0.09559  -8.40649  0.560 38.10533  ? 256 ARG A O   1 
ATOM   2214 C CB  A ARG A 1 256 ? 4.55280   -0.07347 -8.10409  0.440 50.29676  ? 256 ARG A CB  1 
ATOM   2215 C CB  B ARG A 1 256 ? 4.51770   0.11564  -8.02547  0.560 48.53744  ? 256 ARG A CB  1 
ATOM   2216 C CG  A ARG A 1 256 ? 4.43247   0.92501  -6.96658  0.440 46.04230  ? 256 ARG A CG  1 
ATOM   2217 C CG  B ARG A 1 256 ? 3.44978   1.08707  -7.60144  0.560 49.79571  ? 256 ARG A CG  1 
ATOM   2218 C CD  A ARG A 1 256 ? 3.57110   0.37552  -5.82413  0.440 49.60449  ? 256 ARG A CD  1 
ATOM   2219 C CD  B ARG A 1 256 ? 2.74413   0.56059  -6.34931  0.560 51.52711  ? 256 ARG A CD  1 
ATOM   2220 N NE  A ARG A 1 256 ? 2.14486   0.34055  -6.12642  0.440 54.83209  ? 256 ARG A NE  1 
ATOM   2221 N NE  B ARG A 1 256 ? 2.48401   -0.87311 -6.41335  0.560 56.20117  ? 256 ARG A NE  1 
ATOM   2222 C CZ  A ARG A 1 256 ? 1.46170   -0.77323 -6.35156  0.440 59.99152  ? 256 ARG A CZ  1 
ATOM   2223 C CZ  B ARG A 1 256 ? 1.41664   -1.41372 -6.98483  0.560 58.66355  ? 256 ARG A CZ  1 
ATOM   2224 N NH1 A ARG A 1 256 ? 2.04255   -1.96062 -6.29916  0.440 62.02146  ? 256 ARG A NH1 1 
ATOM   2225 N NH1 B ARG A 1 256 ? 0.49111   -0.66620 -7.56581  0.560 57.22411  ? 256 ARG A NH1 1 
ATOM   2226 N NH2 A ARG A 1 256 ? 0.16599   -0.69375 -6.64163  0.440 61.13523  ? 256 ARG A NH2 1 
ATOM   2227 N NH2 B ARG A 1 256 ? 1.27346   -2.73663 -6.97330  0.560 60.34298  ? 256 ARG A NH2 1 
ATOM   2228 N N   A ASN A 1 257 ? 7.26289   -1.41036 -8.79778  0.440 50.67746  ? 257 ASN A N   1 
ATOM   2229 N N   B ASN A 1 257 ? 6.66910   -1.45822 -9.53695  0.560 42.49966  ? 257 ASN A N   1 
ATOM   2230 C CA  A ASN A 1 257 ? 8.11223   -2.49766 -9.26156  0.440 49.52038  ? 257 ASN A CA  1 
ATOM   2231 C CA  B ASN A 1 257 ? 7.75332   -2.42854 -9.48606  0.560 45.82677  ? 257 ASN A CA  1 
ATOM   2232 C C   A ASN A 1 257 ? 9.21535   -1.92261 -10.14467 0.440 44.96633  ? 257 ASN A C   1 
ATOM   2233 C C   B ASN A 1 257 ? 9.03276   -1.84725 -10.07754 0.560 44.35504  ? 257 ASN A C   1 
ATOM   2234 O O   A ASN A 1 257 ? 10.39461  -2.17544 -9.87109  0.440 45.59852  ? 257 ASN A O   1 
ATOM   2235 O O   B ASN A 1 257 ? 10.12887  -2.02914 -9.53570  0.560 47.05257  ? 257 ASN A O   1 
ATOM   2236 C CB  A ASN A 1 257 ? 7.30795   -3.56109 -10.02122 0.440 48.65447  ? 257 ASN A CB  1 
ATOM   2237 C CB  B ASN A 1 257 ? 7.33812   -3.68669 -10.24865 0.560 48.64854  ? 257 ASN A CB  1 
ATOM   2238 C CG  A ASN A 1 257 ? 7.26640   -4.89258 -9.31226  0.440 44.87835  ? 257 ASN A CG  1 
ATOM   2239 C CG  B ASN A 1 257 ? 8.37987   -4.76080 -10.18775 0.560 49.41696  ? 257 ASN A CG  1 
ATOM   2240 O OD1 A ASN A 1 257 ? 7.74207   -5.03336 -8.18756  0.440 45.01189  ? 257 ASN A OD1 1 
ATOM   2241 O OD1 B ASN A 1 257 ? 8.78687   -5.17332 -9.10646  0.560 53.63496  ? 257 ASN A OD1 1 
ATOM   2242 N ND2 A ASN A 1 257 ? 6.68486   -5.88484 -9.97290  0.440 45.74834  ? 257 ASN A ND2 1 
ATOM   2243 N ND2 B ASN A 1 257 ? 8.88029   -5.16839 -11.34366 0.560 50.66952  ? 257 ASN A ND2 1 
ATOM   2244 N N   . TYR A 1 258 ? 8.89842   -1.13884 -11.19339 1.000 42.16440  ? 258 TYR A N   1 
ATOM   2245 C CA  . TYR A 1 258 ? 10.03095  -0.53149 -11.88445 1.000 41.51695  ? 258 TYR A CA  1 
ATOM   2246 C C   . TYR A 1 258 ? 10.70227  0.51673  -11.00362 1.000 41.42886  ? 258 TYR A C   1 
ATOM   2247 O O   . TYR A 1 258 ? 11.92560  0.50354  -10.83559 1.000 43.05829  ? 258 TYR A O   1 
ATOM   2248 C CB  . TYR A 1 258 ? 9.64044   0.10101  -13.22261 1.000 41.05604  ? 258 TYR A CB  1 
ATOM   2249 C CG  . TYR A 1 258 ? 10.84242  0.85806  -13.75626 1.000 38.91445  ? 258 TYR A CG  1 
ATOM   2250 C CD1 . TYR A 1 258 ? 12.00419  0.17169  -14.12640 1.000 39.10580  ? 258 TYR A CD1 1 
ATOM   2251 C CD2 . TYR A 1 258 ? 10.85609  2.24189  -13.80970 1.000 41.47359  ? 258 TYR A CD2 1 
ATOM   2252 C CE1 . TYR A 1 258 ? 13.12908  0.84657  -14.57312 1.000 39.81290  ? 258 TYR A CE1 1 
ATOM   2253 C CE2 . TYR A 1 258 ? 11.98606  2.93906  -14.24989 1.000 40.54304  ? 258 TYR A CE2 1 
ATOM   2254 C CZ  . TYR A 1 258 ? 13.11331  2.23279  -14.62807 1.000 39.47986  ? 258 TYR A CZ  1 
ATOM   2255 O OH  . TYR A 1 258 ? 14.23234  2.90975  -15.04614 1.000 36.51770  ? 258 TYR A OH  1 
ATOM   2256 N N   A ILE A 1 259 ? 9.92008   1.45914  -10.46207 0.680 40.53095  ? 259 ILE A N   1 
ATOM   2257 N N   B ILE A 1 259 ? 9.91629   1.41772  -10.41333 0.320 40.65606  ? 259 ILE A N   1 
ATOM   2258 C CA  A ILE A 1 259 ? 10.48434  2.45518  -9.54529  0.680 39.90477  ? 259 ILE A CA  1 
ATOM   2259 C CA  B ILE A 1 259 ? 10.51225  2.46532  -9.58840  0.320 39.44461  ? 259 ILE A CA  1 
ATOM   2260 C C   A ILE A 1 259 ? 11.31416  1.76525  -8.47841  0.680 42.13513  ? 259 ILE A C   1 
ATOM   2261 C C   B ILE A 1 259 ? 11.22750  1.86662  -8.38081  0.320 41.10674  ? 259 ILE A C   1 
ATOM   2262 O O   A ILE A 1 259 ? 12.45439  2.15079  -8.19512  0.680 43.78150  ? 259 ILE A O   1 
ATOM   2263 O O   B ILE A 1 259 ? 12.22798  2.41932  -7.90813  0.320 39.89928  ? 259 ILE A O   1 
ATOM   2264 C CB  A ILE A 1 259 ? 9.37415   3.29995  -8.89751  0.680 43.99753  ? 259 ILE A CB  1 
ATOM   2265 C CB  B ILE A 1 259 ? 9.43982   3.48948  -9.17212  0.320 40.08910  ? 259 ILE A CB  1 
ATOM   2266 C CG1 A ILE A 1 259 ? 8.77940   4.27746  -9.89386  0.680 44.41548  ? 259 ILE A CG1 1 
ATOM   2267 C CG1 B ILE A 1 259 ? 10.09688  4.74673  -8.60766  0.320 38.32392  ? 259 ILE A CG1 1 
ATOM   2268 C CG2 A ILE A 1 259 ? 9.91478   4.04936  -7.68302  0.680 46.37155  ? 259 ILE A CG2 1 
ATOM   2269 C CG2 B ILE A 1 259 ? 8.48565   2.87931  -8.16886  0.320 40.51184  ? 259 ILE A CG2 1 
ATOM   2270 C CD1 A ILE A 1 259 ? 7.33294   4.55744  -9.61093  0.680 42.40046  ? 259 ILE A CD1 1 
ATOM   2271 C CD1 B ILE A 1 259 ? 9.90283   5.95782  -9.48288  0.320 37.13432  ? 259 ILE A CD1 1 
ATOM   2272 N N   . GLN A 1 260 ? 10.74423  0.72919  -7.86970  1.000 45.98440  ? 260 GLN A N   1 
ATOM   2273 C CA  . GLN A 1 260 ? 11.43237  0.01342  -6.80470  1.000 47.49339  ? 260 GLN A CA  1 
ATOM   2274 C C   . GLN A 1 260 ? 12.69927  -0.67777 -7.28726  1.000 48.08977  ? 260 GLN A C   1 
ATOM   2275 O O   . GLN A 1 260 ? 13.50572  -1.10167 -6.45404  1.000 53.01034  ? 260 GLN A O   1 
ATOM   2276 C CB  . GLN A 1 260 ? 10.49337  -1.01146 -6.16995  1.000 55.37994  ? 260 GLN A CB  1 
ATOM   2277 C CG  . GLN A 1 260 ? 9.21355   -0.41274 -5.61083  1.000 61.48316  ? 260 GLN A CG  1 
ATOM   2278 C CD  . GLN A 1 260 ? 8.43340   -1.40127 -4.76524  1.000 72.04774  ? 260 GLN A CD  1 
ATOM   2279 O OE1 . GLN A 1 260 ? 7.64872   -2.20032 -5.28195  1.000 79.04059  ? 260 GLN A OE1 1 
ATOM   2280 N NE2 . GLN A 1 260 ? 8.66239   -1.36657 -3.45868  1.000 71.52637  ? 260 GLN A NE2 1 
ATOM   2281 N N   . SER A 1 261 ? 12.89928  -0.80948 -8.59861  1.000 41.84720  ? 261 SER A N   1 
ATOM   2282 C CA  . SER A 1 261 ? 14.14298  -1.39756 -9.07069  1.000 42.03022  ? 261 SER A CA  1 
ATOM   2283 C C   . SER A 1 261 ? 15.31592  -0.43423 -8.97236  1.000 39.54779  ? 261 SER A C   1 
ATOM   2284 O O   . SER A 1 261 ? 16.46093  -0.85885 -9.14624  1.000 43.02492  ? 261 SER A O   1 
ATOM   2285 C CB  . SER A 1 261 ? 14.00716  -1.88440 -10.51928 1.000 43.96157  ? 261 SER A CB  1 
ATOM   2286 O OG  . SER A 1 261 ? 13.87826  -0.80327 -11.42564 1.000 42.78998  ? 261 SER A OG  1 
ATOM   2287 N N   . LEU A 1 262 ? 15.06302  0.84044  -8.69817  1.000 38.43981  ? 262 LEU A N   1 
ATOM   2288 C CA  . LEU A 1 262 ? 16.09958  1.86250  -8.72360  1.000 40.28048  ? 262 LEU A CA  1 
ATOM   2289 C C   . LEU A 1 262 ? 16.76432  1.99665  -7.35757  1.000 38.75302  ? 262 LEU A C   1 
ATOM   2290 O O   . LEU A 1 262 ? 16.09873  1.90970  -6.32400  1.000 40.37313  ? 262 LEU A O   1 
ATOM   2291 C CB  . LEU A 1 262 ? 15.49298  3.20211  -9.14611  1.000 39.01267  ? 262 LEU A CB  1 
ATOM   2292 C CG  . LEU A 1 262 ? 14.77651  3.19191  -10.49944 1.000 38.98074  ? 262 LEU A CG  1 
ATOM   2293 C CD1 . LEU A 1 262 ? 14.12548  4.52763  -10.78758 1.000 41.50803  ? 262 LEU A CD1 1 
ATOM   2294 C CD2 . LEU A 1 262 ? 15.76937  2.81870  -11.61707 1.000 37.54174  ? 262 LEU A CD2 1 
ATOM   2295 N N   . THR A 1 263 ? 18.08244  2.20476  -7.35966  1.000 40.91494  ? 263 THR A N   1 
ATOM   2296 C CA  . THR A 1 263 ? 18.79191  2.47672  -6.11569  1.000 41.26697  ? 263 THR A CA  1 
ATOM   2297 C C   . THR A 1 263 ? 18.26576  3.76508  -5.50157  1.000 39.96857  ? 263 THR A C   1 
ATOM   2298 O O   . THR A 1 263 ? 18.08461  4.76955  -6.19575  1.000 38.27759  ? 263 THR A O   1 
ATOM   2299 C CB  . THR A 1 263 ? 20.29620  2.60225  -6.36646  1.000 48.07747  ? 263 THR A CB  1 
ATOM   2300 O OG1 . THR A 1 263 ? 20.82213  1.34067  -6.78594  1.000 53.63469  ? 263 THR A OG1 1 
ATOM   2301 C CG2 . THR A 1 263 ? 21.01025  3.00757  -5.08734  1.000 46.80055  ? 263 THR A CG2 1 
ATOM   2302 N N   . GLN A 1 264 ? 18.01397  3.73934  -4.19612  1.000 36.21043  ? 264 GLN A N   1 
ATOM   2303 C CA  . GLN A 1 264 ? 17.44435  4.90968  -3.54386  1.000 35.54241  ? 264 GLN A CA  1 
ATOM   2304 C C   . GLN A 1 264 ? 18.45697  6.05183  -3.52047  1.000 34.54165  ? 264 GLN A C   1 
ATOM   2305 O O   . GLN A 1 264 ? 19.67534  5.83881  -3.48218  1.000 40.86037  ? 264 GLN A O   1 
ATOM   2306 C CB  . GLN A 1 264 ? 16.99121  4.55686  -2.12840  1.000 37.93545  ? 264 GLN A CB  1 
ATOM   2307 C CG  . GLN A 1 264 ? 16.26365  3.21363  -2.07931  1.000 44.79239  ? 264 GLN A CG  1 
ATOM   2308 C CD  . GLN A 1 264 ? 15.25052  3.06537  -0.95132  1.000 46.52272  ? 264 GLN A CD  1 
ATOM   2309 O OE1 . GLN A 1 264 ? 14.66052  4.03368  -0.47411  1.000 50.42186  ? 264 GLN A OE1 1 
ATOM   2310 N NE2 . GLN A 1 264 ? 15.07224  1.83255  -0.50100  1.000 43.33432  ? 264 GLN A NE2 1 
ATOM   2311 N N   . MET A 1 265 ? 17.93910  7.28005  -3.56086  1.000 31.42581  ? 265 MET A N   1 
ATOM   2312 C CA  . MET A 1 265 ? 18.75237  8.48884  -3.65475  1.000 34.13866  ? 265 MET A CA  1 
ATOM   2313 C C   . MET A 1 265 ? 18.05364  9.54300  -2.81132  1.000 29.23597  ? 265 MET A C   1 
ATOM   2314 O O   . MET A 1 265 ? 16.81244  9.64604  -2.85264  1.000 31.96188  ? 265 MET A O   1 
ATOM   2315 C CB  . MET A 1 265 ? 18.86761  8.99131  -5.09890  1.000 36.56486  ? 265 MET A CB  1 
ATOM   2316 C CG  . MET A 1 265 ? 19.43995  7.99161  -6.07420  1.000 42.26022  ? 265 MET A CG  1 
ATOM   2317 S SD  . MET A 1 265 ? 19.67464  8.76062  -7.69036  1.000 46.32177  ? 265 MET A SD  1 
ATOM   2318 C CE  . MET A 1 265 ? 18.10143  8.31915  -8.43555  1.000 43.25054  ? 265 MET A CE  1 
ATOM   2319 N N   . PRO A 1 266 ? 18.79602  10.33879 -2.05024  1.000 31.71839  ? 266 PRO A N   1 
ATOM   2320 C CA  . PRO A 1 266 ? 18.16662  11.42668 -1.29316  1.000 32.09717  ? 266 PRO A CA  1 
ATOM   2321 C C   . PRO A 1 266 ? 17.95435  12.67089 -2.14322  1.000 32.03212  ? 266 PRO A C   1 
ATOM   2322 O O   . PRO A 1 266 ? 18.62498  12.89843 -3.15032  1.000 32.81973  ? 266 PRO A O   1 
ATOM   2323 C CB  . PRO A 1 266 ? 19.17783  11.70111 -0.17872  1.000 33.77972  ? 266 PRO A CB  1 
ATOM   2324 C CG  . PRO A 1 266 ? 20.48034  11.41380 -0.81432  1.000 34.82642  ? 266 PRO A CG  1 
ATOM   2325 C CD  . PRO A 1 266 ? 20.24137  10.23907 -1.76065  1.000 31.81900  ? 266 PRO A CD  1 
ATOM   2326 N N   . LYS A 1 267 ? 17.00583  13.48935 -1.70644  1.000 29.51339  ? 267 LYS A N   1 
ATOM   2327 C CA  . LYS A 1 267 ? 16.83149  14.81096 -2.29686  1.000 25.92228  ? 267 LYS A CA  1 
ATOM   2328 C C   . LYS A 1 267 ? 18.11592  15.61369 -2.18509  1.000 28.56841  ? 267 LYS A C   1 
ATOM   2329 O O   . LYS A 1 267 ? 18.75837  15.63549 -1.13058  1.000 32.81346  ? 267 LYS A O   1 
ATOM   2330 C CB  . LYS A 1 267 ? 15.69558  15.55983 -1.59530  1.000 28.17242  ? 267 LYS A CB  1 
ATOM   2331 C CG  . LYS A 1 267 ? 15.54268  17.00977 -2.07247  1.000 33.42333  ? 267 LYS A CG  1 
ATOM   2332 C CD  . LYS A 1 267 ? 14.53080  17.78667 -1.22947  1.000 41.21948  ? 267 LYS A CD  1 
ATOM   2333 C CE  . LYS A 1 267 ? 14.63263  19.30523 -1.45397  1.000 42.93353  ? 267 LYS A CE  1 
ATOM   2334 N NZ  . LYS A 1 267 ? 15.97197  19.90589 -1.14254  1.000 41.32732  ? 267 LYS A NZ  1 
ATOM   2335 N N   . MET A 1 268 ? 18.47923  16.27826 -3.27938  1.000 26.97590  ? 268 MET A N   1 
ATOM   2336 C CA  . MET A 1 268 ? 19.67432  17.09710 -3.34924  1.000 28.85547  ? 268 MET A CA  1 
ATOM   2337 C C   . MET A 1 268 ? 19.44645  18.44743 -2.65909  1.000 26.10043  ? 268 MET A C   1 
ATOM   2338 O O   . MET A 1 268 ? 18.31387  18.86770 -2.41030  1.000 29.29852  ? 268 MET A O   1 
ATOM   2339 C CB  . MET A 1 268 ? 20.03722  17.31311 -4.81514  1.000 31.16809  ? 268 MET A CB  1 
ATOM   2340 C CG  . MET A 1 268 ? 20.92405  16.23741 -5.33434  1.000 32.67162  ? 268 MET A CG  1 
ATOM   2341 S SD  . MET A 1 268 ? 21.27198  16.43389 -7.09245  1.000 39.05886  ? 268 MET A SD  1 
ATOM   2342 C CE  . MET A 1 268 ? 23.05425  16.61064 -7.07889  1.000 46.09009  ? 268 MET A CE  1 
ATOM   2343 N N   . ASN A 1 269 ? 20.55336  19.13098 -2.34924  1.000 26.33735  ? 269 ASN A N   1 
ATOM   2344 C CA  . ASN A 1 269 ? 20.52399  20.49085 -1.81196  1.000 26.68527  ? 269 ASN A CA  1 
ATOM   2345 C C   . ASN A 1 269 ? 20.33046  21.46818 -2.97116  1.000 29.95424  ? 269 ASN A C   1 
ATOM   2346 O O   . ASN A 1 269 ? 21.21620  21.61489 -3.81829  1.000 29.30970  ? 269 ASN A O   1 
ATOM   2347 C CB  . ASN A 1 269 ? 21.81780  20.75204 -1.04548  1.000 29.61125  ? 269 ASN A CB  1 
ATOM   2348 C CG  . ASN A 1 269 ? 21.82756  22.09867 -0.35568  1.000 35.68141  ? 269 ASN A CG  1 
ATOM   2349 O OD1 . ASN A 1 269 ? 21.35244  23.07763 -0.90502  1.000 40.62671  ? 269 ASN A OD1 1 
ATOM   2350 N ND2 . ASN A 1 269 ? 22.36691  22.14856 0.85556   1.000 36.66485  ? 269 ASN A ND2 1 
ATOM   2351 N N   . PHE A 1 270 ? 19.16611  22.12271 -3.03260  1.000 28.90426  ? 270 PHE A N   1 
ATOM   2352 C CA  . PHE A 1 270 ? 18.86141  22.96379 -4.19102  1.000 27.89944  ? 270 PHE A CA  1 
ATOM   2353 C C   . PHE A 1 270 ? 19.72753  24.21890 -4.21037  1.000 28.47635  ? 270 PHE A C   1 
ATOM   2354 O O   . PHE A 1 270 ? 19.96274  24.79425 -5.28224  1.000 29.27818  ? 270 PHE A O   1 
ATOM   2355 C CB  . PHE A 1 270 ? 17.38225  23.37074 -4.20386  1.000 27.21640  ? 270 PHE A CB  1 
ATOM   2356 C CG  . PHE A 1 270 ? 16.42738  22.31138 -4.74465  1.000 29.64317  ? 270 PHE A CG  1 
ATOM   2357 C CD1 . PHE A 1 270 ? 16.63457  20.96518 -4.50380  1.000 27.68254  ? 270 PHE A CD1 1 
ATOM   2358 C CD2 . PHE A 1 270 ? 15.29671  22.69212 -5.47270  1.000 31.85976  ? 270 PHE A CD2 1 
ATOM   2359 C CE1 . PHE A 1 270 ? 15.74610  20.01306 -4.96845  1.000 30.55922  ? 270 PHE A CE1 1 
ATOM   2360 C CE2 . PHE A 1 270 ? 14.39686  21.74105 -5.95077  1.000 30.63985  ? 270 PHE A CE2 1 
ATOM   2361 C CZ  . PHE A 1 270 ? 14.63172  20.39581 -5.70726  1.000 31.22452  ? 270 PHE A CZ  1 
ATOM   2362 N N   . ALA A 1 271 ? 20.19299  24.66769 -3.03831  1.000 29.54580  ? 271 ALA A N   1 
ATOM   2363 C CA  . ALA A 1 271 ? 21.12113  25.79958 -3.00141  1.000 31.07487  ? 271 ALA A CA  1 
ATOM   2364 C C   . ALA A 1 271 ? 22.42652  25.47681 -3.70690  1.000 32.25972  ? 271 ALA A C   1 
ATOM   2365 O O   . ALA A 1 271 ? 23.09774  26.38783 -4.23191  1.000 31.82026  ? 271 ALA A O   1 
ATOM   2366 C CB  . ALA A 1 271 ? 21.39879  26.22927 -1.55870  1.000 32.68470  ? 271 ALA A CB  1 
ATOM   2367 N N   . ASN A 1 272 ? 22.81724  24.20246 -3.72537  1.000 31.29803  ? 272 ASN A N   1 
ATOM   2368 C CA  . ASN A 1 272 ? 24.02364  23.79961 -4.43666  1.000 30.92217  ? 272 ASN A CA  1 
ATOM   2369 C C   . ASN A 1 272 ? 23.75601  23.42818 -5.88732  1.000 30.24387  ? 272 ASN A C   1 
ATOM   2370 O O   . ASN A 1 272 ? 24.70926  23.21000 -6.64660  1.000 32.23586  ? 272 ASN A O   1 
ATOM   2371 C CB  . ASN A 1 272 ? 24.69843  22.63389 -3.71543  1.000 32.55785  ? 272 ASN A CB  1 
ATOM   2372 C CG  . ASN A 1 272 ? 25.31386  23.05470 -2.38970  1.000 34.53633  ? 272 ASN A CG  1 
ATOM   2373 O OD1 . ASN A 1 272 ? 25.74946  24.19546 -2.24644  1.000 35.78680  ? 272 ASN A OD1 1 
ATOM   2374 N ND2 . ASN A 1 272 ? 25.37066  22.12894 -1.41845  1.000 34.52664  ? 272 ASN A ND2 1 
ATOM   2375 N N   . VAL A 1 273 ? 22.49179  23.34110 -6.28951  1.000 30.27266  ? 273 VAL A N   1 
ATOM   2376 C CA  . VAL A 1 273 ? 22.14206  23.16019 -7.70216  1.000 29.91739  ? 273 VAL A CA  1 
ATOM   2377 C C   . VAL A 1 273 ? 21.92692  24.50116 -8.38936  1.000 30.88076  ? 273 VAL A C   1 
ATOM   2378 O O   . VAL A 1 273 ? 22.43499  24.74407 -9.48973  1.000 33.35085  ? 273 VAL A O   1 
ATOM   2379 C CB  . VAL A 1 273 ? 20.89013  22.26171 -7.82754  1.000 32.72220  ? 273 VAL A CB  1 
ATOM   2380 C CG1 . VAL A 1 273 ? 20.38805  22.23862 -9.27835  1.000 32.20967  ? 273 VAL A CG1 1 
ATOM   2381 C CG2 . VAL A 1 273 ? 21.18131  20.84203 -7.30722  1.000 33.33698  ? 273 VAL A CG2 1 
ATOM   2382 N N   . PHE A 1 274 ? 21.17418  25.39371 -7.75510  1.000 31.23183  ? 274 PHE A N   1 
ATOM   2383 C CA  . PHE A 1 274 ? 20.89021  26.70735 -8.32561  1.000 29.62213  ? 274 PHE A CA  1 
ATOM   2384 C C   . PHE A 1 274 ? 21.82385  27.74198 -7.69966  1.000 29.05378  ? 274 PHE A C   1 
ATOM   2385 O O   . PHE A 1 274 ? 21.43877  28.62596 -6.91788  1.000 35.85382  ? 274 PHE A O   1 
ATOM   2386 C CB  . PHE A 1 274 ? 19.41744  27.04343 -8.12874  1.000 29.51245  ? 274 PHE A CB  1 
ATOM   2387 C CG  . PHE A 1 274 ? 18.51511  26.02684 -8.74704  1.000 31.38005  ? 274 PHE A CG  1 
ATOM   2388 C CD1 . PHE A 1 274 ? 18.34024  25.99910 -10.12286 1.000 35.36614  ? 274 PHE A CD1 1 
ATOM   2389 C CD2 . PHE A 1 274 ? 17.88618  25.07026 -7.97166  1.000 28.41634  ? 274 PHE A CD2 1 
ATOM   2390 C CE1 . PHE A 1 274 ? 17.53115  25.04250 -10.71984 1.000 34.62611  ? 274 PHE A CE1 1 
ATOM   2391 C CE2 . PHE A 1 274 ? 17.06641  24.11426 -8.56344  1.000 29.12285  ? 274 PHE A CE2 1 
ATOM   2392 C CZ  . PHE A 1 274 ? 16.89776  24.10254 -9.94677  1.000 32.83099  ? 274 PHE A CZ  1 
ATOM   2393 N N   . ILE A 1 275 ? 23.09621  27.59468 -8.06174  1.000 31.40749  ? 275 ILE A N   1 
ATOM   2394 C CA  . ILE A 1 275 ? 24.15407  28.34672 -7.40338  1.000 33.99757  ? 275 ILE A CA  1 
ATOM   2395 C C   . ILE A 1 275 ? 23.93533  29.83484 -7.60567  1.000 35.42237  ? 275 ILE A C   1 
ATOM   2396 O O   . ILE A 1 275 ? 23.75879  30.31460 -8.73474  1.000 33.87388  ? 275 ILE A O   1 
ATOM   2397 C CB  . ILE A 1 275 ? 25.52170  27.90966 -7.93436  1.000 37.07771  ? 275 ILE A CB  1 
ATOM   2398 C CG1 . ILE A 1 275 ? 25.79360  26.45476 -7.57347  1.000 43.08512  ? 275 ILE A CG1 1 
ATOM   2399 C CG2 . ILE A 1 275 ? 26.61511  28.80902 -7.39656  1.000 37.99402  ? 275 ILE A CG2 1 
ATOM   2400 C CD1 . ILE A 1 275 ? 26.64395  25.74158 -8.61813  1.000 46.07524  ? 275 ILE A CD1 1 
ATOM   2401 N N   . GLY A 1 276 ? 23.97199  30.57502 -6.50241  1.000 36.26130  ? 276 GLY A N   1 
ATOM   2402 C CA  . GLY A 1 276 ? 23.81368  32.00392 -6.50867  1.000 40.09085  ? 276 GLY A CA  1 
ATOM   2403 C C   . GLY A 1 276 ? 22.39268  32.50173 -6.63006  1.000 41.20855  ? 276 GLY A C   1 
ATOM   2404 O O   . GLY A 1 276 ? 22.19072  33.71808 -6.65512  1.000 45.45762  ? 276 GLY A O   1 
ATOM   2405 N N   . ALA A 1 277 ? 21.39859  31.62265 -6.72112  1.000 36.48140  ? 277 ALA A N   1 
ATOM   2406 C CA  . ALA A 1 277 ? 20.04128  32.12768 -6.84696  1.000 35.58268  ? 277 ALA A CA  1 
ATOM   2407 C C   . ALA A 1 277 ? 19.54254  32.71459 -5.53126  1.000 35.86876  ? 277 ALA A C   1 
ATOM   2408 O O   . ALA A 1 277 ? 20.01089  32.36033 -4.44868  1.000 39.49468  ? 277 ALA A O   1 
ATOM   2409 C CB  . ALA A 1 277 ? 19.09506  31.02128 -7.30069  1.000 37.41478  ? 277 ALA A CB  1 
ATOM   2410 N N   . ASN A 1 278 ? 18.56841  33.62152 -5.64173  1.000 35.29621  ? 278 ASN A N   1 
ATOM   2411 C CA  . ASN A 1 278 ? 17.80294  34.17358 -4.52786  1.000 37.11850  ? 278 ASN A CA  1 
ATOM   2412 C C   . ASN A 1 278 ? 17.36362  33.03560 -3.60939  1.000 37.86292  ? 278 ASN A C   1 
ATOM   2413 O O   . ASN A 1 278 ? 16.71036  32.09314 -4.07353  1.000 37.30630  ? 278 ASN A O   1 
ATOM   2414 C CB  . ASN A 1 278 ? 16.58795  34.92634 -5.08047  1.000 38.31124  ? 278 ASN A CB  1 
ATOM   2415 C CG  . ASN A 1 278 ? 15.86166  35.75098 -4.03908  1.000 42.04806  ? 278 ASN A CG  1 
ATOM   2416 O OD1 . ASN A 1 278 ? 15.84228  35.42105 -2.85238  1.000 43.15041  ? 278 ASN A OD1 1 
ATOM   2417 N ND2 . ASN A 1 278 ? 15.17825  36.79368 -4.50239  1.000 40.95881  ? 278 ASN A ND2 1 
ATOM   2418 N N   . PRO A 1 279 ? 17.70189  33.06781 -2.31902  1.000 35.20981  ? 279 PRO A N   1 
ATOM   2419 C CA  . PRO A 1 279 ? 17.21995  32.00381 -1.42160  1.000 32.23502  ? 279 PRO A CA  1 
ATOM   2420 C C   . PRO A 1 279 ? 15.71483  31.82544 -1.45694  1.000 34.71784  ? 279 PRO A C   1 
ATOM   2421 O O   . PRO A 1 279 ? 15.23111  30.70088 -1.26692  1.000 35.84099  ? 279 PRO A O   1 
ATOM   2422 C CB  . PRO A 1 279 ? 17.70288  32.45901 -0.04387  1.000 34.14677  ? 279 PRO A CB  1 
ATOM   2423 C CG  . PRO A 1 279 ? 18.93957  33.24945 -0.34396  1.000 35.89950  ? 279 PRO A CG  1 
ATOM   2424 C CD  . PRO A 1 279 ? 18.66660  33.96077 -1.65913  1.000 36.28897  ? 279 PRO A CD  1 
ATOM   2425 N N   . LEU A 1 280 ? 14.94719  32.88987 -1.68748  1.000 31.34393  ? 280 LEU A N   1 
ATOM   2426 C CA  . LEU A 1 280 ? 13.49485  32.69923 -1.77047  1.000 33.23409  ? 280 LEU A CA  1 
ATOM   2427 C C   . LEU A 1 280 ? 13.08576  31.96875 -3.04096  1.000 33.27162  ? 280 LEU A C   1 
ATOM   2428 O O   . LEU A 1 280 ? 12.08616  31.22954 -3.03232  1.000 29.45526  ? 280 LEU A O   1 
ATOM   2429 C CB  . LEU A 1 280 ? 12.74776  34.02653 -1.66708  1.000 32.82256  ? 280 LEU A CB  1 
ATOM   2430 C CG  . LEU A 1 280 ? 12.91919  34.75376 -0.33259  1.000 34.60867  ? 280 LEU A CG  1 
ATOM   2431 C CD1 . LEU A 1 280 ? 12.49522  36.21943 -0.43491  1.000 35.84472  ? 280 LEU A CD1 1 
ATOM   2432 C CD2 . LEU A 1 280 ? 12.18442  34.02211 0.77105   1.000 38.68484  ? 280 LEU A CD2 1 
ATOM   2433 N N   . ALA A 1 281 ? 13.82400  32.16489 -4.14224  1.000 30.73578  ? 281 ALA A N   1 
ATOM   2434 C CA  . ALA A 1 281 ? 13.54990  31.38067 -5.34644  1.000 33.80008  ? 281 ALA A CA  1 
ATOM   2435 C C   . ALA A 1 281 ? 13.82752  29.90369 -5.10969  1.000 30.41984  ? 281 ALA A C   1 
ATOM   2436 O O   . ALA A 1 281 ? 13.05368  29.04267 -5.56600  1.000 30.06974  ? 281 ALA A O   1 
ATOM   2437 C CB  . ALA A 1 281 ? 14.37487  31.90112 -6.53230  1.000 32.03270  ? 281 ALA A CB  1 
ATOM   2438 N N   . VAL A 1 282 ? 14.92478  29.59078 -4.39889  1.000 30.01368  ? 282 VAL A N   1 
ATOM   2439 C CA  . VAL A 1 282 ? 15.25642  28.19948 -4.10320  1.000 32.36309  ? 282 VAL A CA  1 
ATOM   2440 C C   . VAL A 1 282 ? 14.15028  27.56312 -3.26469  1.000 32.31940  ? 282 VAL A C   1 
ATOM   2441 O O   . VAL A 1 282 ? 13.70967  26.43263 -3.53624  1.000 30.97222  ? 282 VAL A O   1 
ATOM   2442 C CB  . VAL A 1 282 ? 16.62868  28.11534 -3.39351  1.000 32.89622  ? 282 VAL A CB  1 
ATOM   2443 C CG1 . VAL A 1 282 ? 16.92490  26.66984 -2.94808  1.000 36.91672  ? 282 VAL A CG1 1 
ATOM   2444 C CG2 . VAL A 1 282 ? 17.74151  28.65321 -4.27417  1.000 35.68917  ? 282 VAL A CG2 1 
ATOM   2445 N N   . ASP A 1 283 ? 13.67033  28.28446 -2.24383  1.000 29.53342  ? 283 ASP A N   1 
ATOM   2446 C CA  . ASP A 1 283 ? 12.59259  27.76438 -1.40379  1.000 31.27407  ? 283 ASP A CA  1 
ATOM   2447 C C   . ASP A 1 283 ? 11.34066  27.47433 -2.23165  1.000 28.29945  ? 283 ASP A C   1 
ATOM   2448 O O   . ASP A 1 283 ? 10.69649  26.43355 -2.06416  1.000 30.69331  ? 283 ASP A O   1 
ATOM   2449 C CB  . ASP A 1 283 ? 12.25718  28.75641 -0.29411  1.000 33.17750  ? 283 ASP A CB  1 
ATOM   2450 C CG  . ASP A 1 283 ? 11.28901  28.18190 0.71798   1.000 35.46304  ? 283 ASP A CG  1 
ATOM   2451 O OD1 . ASP A 1 283 ? 11.65022  27.22450 1.44959   1.000 36.20302  ? 283 ASP A OD1 1 
ATOM   2452 O OD2 . ASP A 1 283 ? 10.12202  28.62987 0.71280   1.000 34.27819  ? 283 ASP A OD2 1 
ATOM   2453 N N   . LEU A 1 284 ? 10.96760  28.39507 -3.12318  1.000 28.52776  ? 284 LEU A N   1 
ATOM   2454 C CA  . LEU A 1 284 ? 9.78525   28.16521 -3.94238  1.000 26.75238  ? 284 LEU A CA  1 
ATOM   2455 C C   . LEU A 1 284 ? 9.98429   26.97220 -4.86761  1.000 31.48127  ? 284 LEU A C   1 
ATOM   2456 O O   . LEU A 1 284 ? 9.06371   26.16575 -5.05289  1.000 30.66449  ? 284 LEU A O   1 
ATOM   2457 C CB  . LEU A 1 284 ? 9.43021   29.42937 -4.73462  1.000 27.71338  ? 284 LEU A CB  1 
ATOM   2458 C CG  . LEU A 1 284 ? 8.17502   29.33595 -5.59721  1.000 26.90395  ? 284 LEU A CG  1 
ATOM   2459 C CD1 . LEU A 1 284 ? 6.89675   29.05673 -4.75637  1.000 27.97727  ? 284 LEU A CD1 1 
ATOM   2460 C CD2 . LEU A 1 284 ? 7.98712   30.56627 -6.49914  1.000 31.36645  ? 284 LEU A CD2 1 
ATOM   2461 N N   . LEU A 1 285 ? 11.18118  26.82727 -5.44065  1.000 29.17783  ? 285 LEU A N   1 
ATOM   2462 C CA  . LEU A 1 285 ? 11.44815  25.66903 -6.29174  1.000 27.54280  ? 285 LEU A CA  1 
ATOM   2463 C C   . LEU A 1 285 ? 11.32580  24.37928 -5.49840  1.000 29.46060  ? 285 LEU A C   1 
ATOM   2464 O O   . LEU A 1 285 ? 10.79271  23.38285 -6.00357  1.000 30.84007  ? 285 LEU A O   1 
ATOM   2465 C CB  . LEU A 1 285 ? 12.83902  25.78292 -6.92542  1.000 30.71426  ? 285 LEU A CB  1 
ATOM   2466 C CG  . LEU A 1 285 ? 12.95120  26.77549 -8.08320  1.000 32.66999  ? 285 LEU A CG  1 
ATOM   2467 C CD1 . LEU A 1 285 ? 14.41317  26.97734 -8.46714  1.000 36.91741  ? 285 LEU A CD1 1 
ATOM   2468 C CD2 . LEU A 1 285 ? 12.12168  26.31024 -9.29726  1.000 32.98486  ? 285 LEU A CD2 1 
ATOM   2469 N N   . GLU A 1 286 ? 11.78895  24.37839 -4.24066  1.000 27.67732  ? 286 GLU A N   1 
ATOM   2470 C CA  . GLU A 1 286 ? 11.68363  23.15995 -3.44773  1.000 28.42120  ? 286 GLU A CA  1 
ATOM   2471 C C   . GLU A 1 286 ? 10.21558  22.79686 -3.21336  1.000 32.16440  ? 286 GLU A C   1 
ATOM   2472 O O   . GLU A 1 286 ? 9.86879   21.61394 -3.08436  1.000 33.22833  ? 286 GLU A O   1 
ATOM   2473 C CB  . GLU A 1 286 ? 12.42889  23.33668 -2.12395  1.000 29.99375  ? 286 GLU A CB  1 
ATOM   2474 C CG  . GLU A 1 286 ? 13.95906  23.13278 -2.29806  1.000 32.55279  ? 286 GLU A CG  1 
ATOM   2475 C CD  . GLU A 1 286 ? 14.76530  23.26870 -1.01653  1.000 47.29476  ? 286 GLU A CD  1 
ATOM   2476 O OE1 . GLU A 1 286 ? 14.32611  24.00062 -0.09266  1.000 47.15677  ? 286 GLU A OE1 1 
ATOM   2477 O OE2 . GLU A 1 286 ? 15.84859  22.63529 -0.94624  1.000 46.78622  ? 286 GLU A OE2 1 
ATOM   2478 N N   . LYS A 1 287 ? 9.34013   23.79570 -3.18841  1.000 26.74695  ? 287 LYS A N   1 
ATOM   2479 C CA  . LYS A 1 287 ? 7.92532   23.56072 -2.93372  1.000 26.89824  ? 287 LYS A CA  1 
ATOM   2480 C C   . LYS A 1 287 ? 7.13307   23.23645 -4.19630  1.000 27.50902  ? 287 LYS A C   1 
ATOM   2481 O O   . LYS A 1 287 ? 6.07508   22.59794 -4.09603  1.000 28.67887  ? 287 LYS A O   1 
ATOM   2482 C CB  . LYS A 1 287 ? 7.33188   24.77651 -2.22776  1.000 29.88076  ? 287 LYS A CB  1 
ATOM   2483 C CG  . LYS A 1 287 ? 7.69871   24.78081 -0.74175  1.000 33.72946  ? 287 LYS A CG  1 
ATOM   2484 C CD  . LYS A 1 287 ? 7.58631   26.14140 -0.11984  1.000 39.72487  ? 287 LYS A CD  1 
ATOM   2485 C CE  . LYS A 1 287 ? 7.99753   26.07577 1.35410   1.000 44.27796  ? 287 LYS A CE  1 
ATOM   2486 N NZ  . LYS A 1 287 ? 8.29267   27.44184 1.86546   1.000 49.27953  ? 287 LYS A NZ  1 
ATOM   2487 N N   . MET A 1 288 ? 7.60457   23.64084 -5.37572  1.000 29.55383  ? 288 MET A N   1 
ATOM   2488 C CA  . MET A 1 288 ? 6.90671   23.17043 -6.56768  1.000 29.82270  ? 288 MET A CA  1 
ATOM   2489 C C   . MET A 1 288 ? 7.43697   21.85287 -7.10120  1.000 29.05816  ? 288 MET A C   1 
ATOM   2490 O O   . MET A 1 288 ? 6.64619   21.05641 -7.62656  1.000 31.63248  ? 288 MET A O   1 
ATOM   2491 C CB  . MET A 1 288 ? 6.84967   24.22139 -7.68988  1.000 32.77873  ? 288 MET A CB  1 
ATOM   2492 C CG  . MET A 1 288 ? 6.76590   25.69563 -7.30281  1.000 27.88556  ? 288 MET A CG  1 
ATOM   2493 S SD  . MET A 1 288 ? 7.24764   26.74214 -8.72340  1.000 37.59848  ? 288 MET A SD  1 
ATOM   2494 C CE  . MET A 1 288 ? 6.18575   28.13051 -8.53983  1.000 36.06747  ? 288 MET A CE  1 
ATOM   2495 N N   . LEU A 1 289 ? 8.71958   21.55850 -6.94363  1.000 25.45505  ? 289 LEU A N   1 
ATOM   2496 C CA  . LEU A 1 289 ? 9.27278   20.33484 -7.52017  1.000 24.41446  ? 289 LEU A CA  1 
ATOM   2497 C C   . LEU A 1 289 ? 9.27193   19.20722 -6.48374  1.000 28.08146  ? 289 LEU A C   1 
ATOM   2498 O O   . LEU A 1 289 ? 10.29533  18.63479 -6.12721  1.000 31.89106  ? 289 LEU A O   1 
ATOM   2499 C CB  . LEU A 1 289 ? 10.67327  20.60415 -8.05299  1.000 23.59968  ? 289 LEU A CB  1 
ATOM   2500 C CG  . LEU A 1 289 ? 10.72007  21.59270 -9.23376  1.000 23.56340  ? 289 LEU A CG  1 
ATOM   2501 C CD1 . LEU A 1 289 ? 12.16321  21.94656 -9.56752  1.000 29.16794  ? 289 LEU A CD1 1 
ATOM   2502 C CD2 . LEU A 1 289 ? 10.03248  21.03239 -10.48852 1.000 28.21056  ? 289 LEU A CD2 1 
ATOM   2503 N N   . VAL A 1 290 ? 8.07785   18.89313 -6.00120  1.000 28.60944  ? 290 VAL A N   1 
ATOM   2504 C CA  . VAL A 1 290 ? 7.84106   17.79648 -5.06571  1.000 28.69118  ? 290 VAL A CA  1 
ATOM   2505 C C   . VAL A 1 290 ? 7.25528   16.63831 -5.85340  1.000 28.58091  ? 290 VAL A C   1 
ATOM   2506 O O   . VAL A 1 290 ? 6.32923   16.83207 -6.64515  1.000 31.84731  ? 290 VAL A O   1 
ATOM   2507 C CB  . VAL A 1 290 ? 6.88139   18.22164 -3.93760  1.000 34.77089  ? 290 VAL A CB  1 
ATOM   2508 C CG1 . VAL A 1 290 ? 6.65420   17.08086 -2.98213  1.000 32.63565  ? 290 VAL A CG1 1 
ATOM   2509 C CG2 . VAL A 1 290 ? 7.46676   19.38183 -3.16572  1.000 37.71724  ? 290 VAL A CG2 1 
ATOM   2510 N N   . LEU A 1 291 ? 7.78492   15.43088 -5.63870  1.000 28.41591  ? 291 LEU A N   1 
ATOM   2511 C CA  . LEU A 1 291 ? 7.34877   14.29034 -6.43397  1.000 31.11210  ? 291 LEU A CA  1 
ATOM   2512 C C   . LEU A 1 291 ? 5.88093   13.95670 -6.16801  1.000 29.95048  ? 291 LEU A C   1 
ATOM   2513 O O   . LEU A 1 291 ? 5.11045   13.72254 -7.10545  1.000 33.60473  ? 291 LEU A O   1 
ATOM   2514 C CB  . LEU A 1 291 ? 8.25601   13.09132 -6.14509  1.000 36.11999  ? 291 LEU A CB  1 
ATOM   2515 C CG  . LEU A 1 291 ? 8.44017   12.02548 -7.21157  1.000 40.53942  ? 291 LEU A CG  1 
ATOM   2516 C CD1 . LEU A 1 291 ? 8.88398   12.60656 -8.55946  1.000 36.09814  ? 291 LEU A CD1 1 
ATOM   2517 C CD2 . LEU A 1 291 ? 9.43781   10.96944 -6.70181  1.000 41.37023  ? 291 LEU A CD2 1 
ATOM   2518 N N   . ASP A 1 292 ? 5.47290   13.91871 -4.89145  1.000 29.22714  ? 292 ASP A N   1 
ATOM   2519 C CA  . ASP A 1 292 ? 4.08272   13.63298 -4.53113  1.000 31.83787  ? 292 ASP A CA  1 
ATOM   2520 C C   . ASP A 1 292 ? 3.19152   14.83512 -4.86417  1.000 30.50755  ? 292 ASP A C   1 
ATOM   2521 O O   . ASP A 1 292 ? 3.24661   15.86590 -4.18305  1.000 32.75291  ? 292 ASP A O   1 
ATOM   2522 C CB  . ASP A 1 292 ? 4.00711   13.30419 -3.04309  1.000 33.03615  ? 292 ASP A CB  1 
ATOM   2523 C CG  . ASP A 1 292 ? 2.67820   12.68650 -2.64062  1.000 35.60091  ? 292 ASP A CG  1 
ATOM   2524 O OD1 . ASP A 1 292 ? 1.65921   12.99691 -3.29917  1.000 34.57218  ? 292 ASP A OD1 1 
ATOM   2525 O OD2 . ASP A 1 292 ? 2.64040   11.96553 -1.61329  1.000 37.35669  ? 292 ASP A OD2 1 
ATOM   2526 N N   . SER A 1 293 ? 2.33416   14.71012 -5.88350  1.000 29.24624  ? 293 SER A N   1 
ATOM   2527 C CA  . SER A 1 293 ? 1.50572   15.85381 -6.27072  1.000 32.48658  ? 293 SER A CA  1 
ATOM   2528 C C   . SER A 1 293 ? 0.51857   16.28599 -5.18478  1.000 33.42152  ? 293 SER A C   1 
ATOM   2529 O O   . SER A 1 293 ? 0.03548   17.42362 -5.23692  1.000 38.09830  ? 293 SER A O   1 
ATOM   2530 C CB  . SER A 1 293 ? 0.74560   15.56178 -7.57327  1.000 35.20463  ? 293 SER A CB  1 
ATOM   2531 O OG  . SER A 1 293 ? -0.17455  14.49143 -7.43282  1.000 35.44467  ? 293 SER A OG  1 
ATOM   2532 N N   . ASP A 1 294 ? 0.20864   15.42027 -4.20871  1.000 30.00376  ? 294 ASP A N   1 
ATOM   2533 C CA  . ASP A 1 294 ? -0.66347  15.82398 -3.10789  1.000 33.57384  ? 294 ASP A CA  1 
ATOM   2534 C C   . ASP A 1 294 ? -0.01579  16.91441 -2.26115  1.000 34.10311  ? 294 ASP A C   1 
ATOM   2535 O O   . ASP A 1 294 ? -0.71390  17.62390 -1.53346  1.000 31.20732  ? 294 ASP A O   1 
ATOM   2536 C CB  . ASP A 1 294 ? -0.98144  14.64362 -2.17689  1.000 36.87087  ? 294 ASP A CB  1 
ATOM   2537 C CG  . ASP A 1 294 ? -2.03291  13.69289 -2.73229  1.000 42.72475  ? 294 ASP A CG  1 
ATOM   2538 O OD1 . ASP A 1 294 ? -2.72370  14.03859 -3.71420  1.000 43.15541  ? 294 ASP A OD1 1 
ATOM   2539 O OD2 . ASP A 1 294 ? -2.16906  12.58564 -2.15534  1.000 43.99161  ? 294 ASP A OD2 1 
ATOM   2540 N N   . LYS A 1 295 ? 1.31062   17.03336 -2.31376  1.000 32.31866  ? 295 LYS A N   1 
ATOM   2541 C CA  . LYS A 1 295 ? 2.06877   17.89438 -1.41456  1.000 29.48826  ? 295 LYS A CA  1 
ATOM   2542 C C   . LYS A 1 295 ? 2.69429   19.08729 -2.11966  1.000 25.82910  ? 295 LYS A C   1 
ATOM   2543 O O   . LYS A 1 295 ? 3.32188   19.91991 -1.46103  1.000 29.52179  ? 295 LYS A O   1 
ATOM   2544 C CB  . LYS A 1 295 ? 3.15826   17.07908 -0.71228  1.000 30.36099  ? 295 LYS A CB  1 
ATOM   2545 C CG  . LYS A 1 295 ? 2.64220   15.76377 -0.09314  1.000 40.63816  ? 295 LYS A CG  1 
ATOM   2546 C CD  . LYS A 1 295 ? 3.44485   15.37211 1.13098   1.000 45.14669  ? 295 LYS A CD  1 
ATOM   2547 C CE  . LYS A 1 295 ? 2.63981   14.45371 2.04947   1.000 49.34725  ? 295 LYS A CE  1 
ATOM   2548 N NZ  . LYS A 1 295 ? 3.43447   13.28139 2.53089   1.000 53.89719  ? 295 LYS A NZ  1 
ATOM   2549 N N   . ARG A 1 296 ? 2.56126   19.17484 -3.43796  1.000 26.97072  ? 296 ARG A N   1 
ATOM   2550 C CA  . ARG A 1 296 ? 3.03276   20.33092 -4.18746  1.000 28.53433  ? 296 ARG A CA  1 
ATOM   2551 C C   . ARG A 1 296 ? 2.24836   21.58450 -3.80633  1.000 26.06175  ? 296 ARG A C   1 
ATOM   2552 O O   . ARG A 1 296 ? 1.05366   21.52496 -3.51957  1.000 29.57167  ? 296 ARG A O   1 
ATOM   2553 C CB  . ARG A 1 296 ? 2.85722   20.07585 -5.67829  1.000 31.46548  ? 296 ARG A CB  1 
ATOM   2554 C CG  . ARG A 1 296 ? 4.08675   19.81680 -6.46205  1.000 35.76566  ? 296 ARG A CG  1 
ATOM   2555 C CD  . ARG A 1 296 ? 3.71874   19.30889 -7.86615  1.000 30.47952  ? 296 ARG A CD  1 
ATOM   2556 N NE  . ARG A 1 296 ? 4.28293   17.98454 -8.09036  1.000 31.39138  ? 296 ARG A NE  1 
ATOM   2557 C CZ  . ARG A 1 296 ? 3.87847   17.13207 -9.01848  1.000 27.13474  ? 296 ARG A CZ  1 
ATOM   2558 N NH1 . ARG A 1 296 ? 2.90155   17.44084 -9.86990  1.000 30.07927  ? 296 ARG A NH1 1 
ATOM   2559 N NH2 . ARG A 1 296 ? 4.44989   15.93145 -9.08137  1.000 29.23066  ? 296 ARG A NH2 1 
ATOM   2560 N N   . ILE A 1 297 ? 2.92982   22.73493 -3.82635  1.000 26.15632  ? 297 ILE A N   1 
ATOM   2561 C CA  . ILE A 1 297 ? 2.24933   24.01613 -3.61314  1.000 26.18174  ? 297 ILE A CA  1 
ATOM   2562 C C   . ILE A 1 297 ? 1.24216   24.27135 -4.73785  1.000 26.72998  ? 297 ILE A C   1 
ATOM   2563 O O   . ILE A 1 297 ? 1.47903   23.91237 -5.90110  1.000 27.33247  ? 297 ILE A O   1 
ATOM   2564 C CB  . ILE A 1 297 ? 3.30239   25.13748 -3.53149  1.000 26.73584  ? 297 ILE A CB  1 
ATOM   2565 C CG1 . ILE A 1 297 ? 2.72600   26.43805 -2.95590  1.000 25.91225  ? 297 ILE A CG1 1 
ATOM   2566 C CG2 . ILE A 1 297 ? 3.94632   25.39831 -4.88614  1.000 28.57027  ? 297 ILE A CG2 1 
ATOM   2567 C CD1 . ILE A 1 297 ? 3.83588   27.32260 -2.33831  1.000 28.12018  ? 297 ILE A CD1 1 
ATOM   2568 N N   . THR A 1 298 ? 0.10383   24.89600 -4.40214  1.000 25.84273  ? 298 THR A N   1 
ATOM   2569 C CA  . THR A 1 298 ? -0.86314  25.27440 -5.41807  1.000 25.03708  ? 298 THR A CA  1 
ATOM   2570 C C   . THR A 1 298 ? -0.55526  26.67382 -5.95317  1.000 27.49456  ? 298 THR A C   1 
ATOM   2571 O O   . THR A 1 298 ? 0.22315   27.43162 -5.36817  1.000 29.88639  ? 298 THR A O   1 
ATOM   2572 C CB  . THR A 1 298 ? -2.29533  25.26979 -4.86718  1.000 27.84943  ? 298 THR A CB  1 
ATOM   2573 O OG1 . THR A 1 298 ? -2.42485  26.33602 -3.92733  1.000 29.57579  ? 298 THR A OG1 1 
ATOM   2574 C CG2 . THR A 1 298 ? -2.66771  23.92982 -4.19177  1.000 31.84913  ? 298 THR A CG2 1 
ATOM   2575 N N   . ALA A 1 299 ? -1.21867  27.04797 -7.05172  1.000 26.14763  ? 299 ALA A N   1 
ATOM   2576 C CA  . ALA A 1 299 ? -1.00545  28.39960 -7.57708  1.000 25.13097  ? 299 ALA A CA  1 
ATOM   2577 C C   . ALA A 1 299 ? -1.37336  29.45892 -6.54365  1.000 26.79893  ? 299 ALA A C   1 
ATOM   2578 O O   . ALA A 1 299 ? -0.60943  30.40665 -6.31123  1.000 25.97169  ? 299 ALA A O   1 
ATOM   2579 C CB  . ALA A 1 299 ? -1.78688  28.61656 -8.87663  1.000 28.08376  ? 299 ALA A CB  1 
ATOM   2580 N N   . ALA A 1 300 ? -2.53755  29.31330 -5.90339  1.000 26.19049  ? 300 ALA A N   1 
ATOM   2581 C CA  . ALA A 1 300 ? -2.96989  30.31095 -4.93046  1.000 27.04334  ? 300 ALA A CA  1 
ATOM   2582 C C   . ALA A 1 300 ? -1.98870  30.42428 -3.77225  1.000 29.63545  ? 300 ALA A C   1 
ATOM   2583 O O   . ALA A 1 300 ? -1.72814  31.52833 -3.27097  1.000 32.43731  ? 300 ALA A O   1 
ATOM   2584 C CB  . ALA A 1 300 ? -4.36586  29.96871 -4.40317  1.000 29.75412  ? 300 ALA A CB  1 
ATOM   2585 N N   . GLN A 1 301 ? -1.48060  29.28773 -3.29128  1.000 27.90521  ? 301 GLN A N   1 
ATOM   2586 C CA  . GLN A 1 301 ? -0.48223  29.33259 -2.22497  1.000 26.28126  ? 301 GLN A CA  1 
ATOM   2587 C C   . GLN A 1 301 ? 0.80912   29.97698 -2.71149  1.000 27.49339  ? 301 GLN A C   1 
ATOM   2588 O O   . GLN A 1 301 ? 1.45459   30.72808 -1.97121  1.000 31.34322  ? 301 GLN A O   1 
ATOM   2589 C CB  . GLN A 1 301 ? -0.20267  27.92597 -1.69720  1.000 26.68456  ? 301 GLN A CB  1 
ATOM   2590 C CG  . GLN A 1 301 ? -1.46191  27.31122 -1.05832  1.000 30.90408  ? 301 GLN A CG  1 
ATOM   2591 C CD  . GLN A 1 301 ? -1.45376  25.79284 -1.04871  1.000 33.58632  ? 301 GLN A CD  1 
ATOM   2592 O OE1 . GLN A 1 301 ? -0.49643  25.14643 -1.51437  1.000 29.43372  ? 301 GLN A OE1 1 
ATOM   2593 N NE2 . GLN A 1 301 ? -2.54109  25.20982 -0.54370  1.000 33.86242  ? 301 GLN A NE2 1 
ATOM   2594 N N   . ALA A 1 302 ? 1.21261   29.69391 -3.94952  1.000 27.46906  ? 302 ALA A N   1 
ATOM   2595 C CA  . ALA A 1 302 ? 2.48999   30.23441 -4.42254  1.000 27.15617  ? 302 ALA A CA  1 
ATOM   2596 C C   . ALA A 1 302 ? 2.42650   31.74835 -4.60484  1.000 30.88911  ? 302 ALA A C   1 
ATOM   2597 O O   . ALA A 1 302 ? 3.43150   32.43386 -4.38780  1.000 29.30520  ? 302 ALA A O   1 
ATOM   2598 C CB  . ALA A 1 302 ? 2.92704   29.54806 -5.72787  1.000 28.76378  ? 302 ALA A CB  1 
ATOM   2599 N N   . LEU A 1 303 ? 1.26630   32.30097 -4.98652  1.000 31.41822  ? 303 LEU A N   1 
ATOM   2600 C CA  . LEU A 1 303 ? 1.17428   33.75399 -5.12723  1.000 28.92083  ? 303 LEU A CA  1 
ATOM   2601 C C   . LEU A 1 303 ? 1.46009   34.47045 -3.81247  1.000 28.45345  ? 303 LEU A C   1 
ATOM   2602 O O   . LEU A 1 303 ? 1.91256   35.62131 -3.82411  1.000 31.98630  ? 303 LEU A O   1 
ATOM   2603 C CB  . LEU A 1 303 ? -0.20694  34.14786 -5.66218  1.000 30.27606  ? 303 LEU A CB  1 
ATOM   2604 C CG  . LEU A 1 303 ? -0.48467  33.81399 -7.14728  1.000 30.04822  ? 303 LEU A CG  1 
ATOM   2605 C CD1 . LEU A 1 303 ? -1.98350  33.94919 -7.42949  1.000 33.71349  ? 303 LEU A CD1 1 
ATOM   2606 C CD2 . LEU A 1 303 ? 0.31949   34.69438 -8.12650  1.000 29.78694  ? 303 LEU A CD2 1 
ATOM   2607 N N   . ALA A 1 304 ? 1.21066   33.82190 -2.67548  1.000 30.70753  ? 304 ALA A N   1 
ATOM   2608 C CA  . ALA A 1 304 ? 1.44142   34.42013 -1.36152  1.000 31.92336  ? 304 ALA A CA  1 
ATOM   2609 C C   . ALA A 1 304 ? 2.86044   34.19928 -0.83763  1.000 31.83221  ? 304 ALA A C   1 
ATOM   2610 O O   . ALA A 1 304 ? 3.16988   34.64771 0.27347   1.000 31.77016  ? 304 ALA A O   1 
ATOM   2611 C CB  . ALA A 1 304 ? 0.41047   33.87514 -0.34894  1.000 30.29779  ? 304 ALA A CB  1 
ATOM   2612 N N   . HIS A 1 305 ? 3.71610   33.51515 -1.59526  1.000 29.82495  ? 305 HIS A N   1 
ATOM   2613 C CA  . HIS A 1 305 ? 5.09643   33.25810 -1.18756  1.000 30.55279  ? 305 HIS A CA  1 
ATOM   2614 C C   . HIS A 1 305 ? 5.89992   34.54869 -1.21911  1.000 32.57597  ? 305 HIS A C   1 
ATOM   2615 O O   . HIS A 1 305 ? 5.71113   35.38997 -2.10723  1.000 31.68366  ? 305 HIS A O   1 
ATOM   2616 C CB  . HIS A 1 305 ? 5.73532   32.22120 -2.12609  1.000 29.74586  ? 305 HIS A CB  1 
ATOM   2617 C CG  . HIS A 1 305 ? 7.05452   31.67621 -1.65664  1.000 30.97562  ? 305 HIS A CG  1 
ATOM   2618 N ND1 . HIS A 1 305 ? 8.25346   32.29887 -1.93623  1.000 31.75655  ? 305 HIS A ND1 1 
ATOM   2619 C CD2 . HIS A 1 305 ? 7.37276   30.52329 -1.01472  1.000 34.58739  ? 305 HIS A CD2 1 
ATOM   2620 C CE1 . HIS A 1 305 ? 9.24921   31.58304 -1.43404  1.000 32.83106  ? 305 HIS A CE1 1 
ATOM   2621 N NE2 . HIS A 1 305 ? 8.74224   30.49691 -0.87609  1.000 32.21823  ? 305 HIS A NE2 1 
ATOM   2622 N N   . ALA A 1 306 ? 6.82576   34.68940 -0.26286  1.000 32.63466  ? 306 ALA A N   1 
ATOM   2623 C CA  . ALA A 1 306 ? 7.57602   35.93462 -0.14876  1.000 32.39594  ? 306 ALA A CA  1 
ATOM   2624 C C   . ALA A 1 306 ? 8.38192   36.24911 -1.40124  1.000 34.17725  ? 306 ALA A C   1 
ATOM   2625 O O   . ALA A 1 306 ? 8.80470   37.39749 -1.57605  1.000 35.44984  ? 306 ALA A O   1 
ATOM   2626 C CB  . ALA A 1 306 ? 8.49644   35.89044 1.07626   1.000 35.62601  ? 306 ALA A CB  1 
ATOM   2627 N N   . TYR A 1 307 ? 8.61836   35.26528 -2.27729  1.000 32.05572  ? 307 TYR A N   1 
ATOM   2628 C CA  . TYR A 1 307 ? 9.35514   35.56917 -3.50647  1.000 31.97237  ? 307 TYR A CA  1 
ATOM   2629 C C   . TYR A 1 307 ? 8.63821   36.62786 -4.34501  1.000 32.81959  ? 307 TYR A C   1 
ATOM   2630 O O   . TYR A 1 307 ? 9.29281   37.41771 -5.03910  1.000 35.25993  ? 307 TYR A O   1 
ATOM   2631 C CB  . TYR A 1 307 ? 9.57952   34.28276 -4.30555  1.000 29.31214  ? 307 TYR A CB  1 
ATOM   2632 C CG  . TYR A 1 307 ? 10.44564  34.42007 -5.54738  1.000 32.20519  ? 307 TYR A CG  1 
ATOM   2633 C CD1 . TYR A 1 307 ? 11.72524  34.97076 -5.48345  1.000 32.02829  ? 307 TYR A CD1 1 
ATOM   2634 C CD2 . TYR A 1 307 ? 9.97844   33.98731 -6.79807  1.000 33.12368  ? 307 TYR A CD2 1 
ATOM   2635 C CE1 . TYR A 1 307 ? 12.52031  35.08038 -6.63641  1.000 34.04815  ? 307 TYR A CE1 1 
ATOM   2636 C CE2 . TYR A 1 307 ? 10.76497  34.09442 -7.94199  1.000 33.28414  ? 307 TYR A CE2 1 
ATOM   2637 C CZ  . TYR A 1 307 ? 12.03616  34.64446 -7.85223  1.000 34.31151  ? 307 TYR A CZ  1 
ATOM   2638 O OH  . TYR A 1 307 ? 12.82657  34.75217 -8.98917  1.000 36.58080  ? 307 TYR A OH  1 
ATOM   2639 N N   . PHE A 1 308 ? 7.30414   36.67886 -4.27936  1.000 33.60568  ? 308 PHE A N   1 
ATOM   2640 C CA  . PHE A 1 308 ? 6.49886   37.59001 -5.09041  1.000 32.59060  ? 308 PHE A CA  1 
ATOM   2641 C C   . PHE A 1 308 ? 6.01713   38.81399 -4.31089  1.000 35.39009  ? 308 PHE A C   1 
ATOM   2642 O O   . PHE A 1 308 ? 5.07255   39.48413 -4.74242  1.000 36.71441  ? 308 PHE A O   1 
ATOM   2643 C CB  . PHE A 1 308 ? 5.29616   36.84298 -5.68262  1.000 31.87303  ? 308 PHE A CB  1 
ATOM   2644 C CG  . PHE A 1 308 ? 5.68047   35.64748 -6.50952  1.000 30.30159  ? 308 PHE A CG  1 
ATOM   2645 C CD1 . PHE A 1 308 ? 6.42914   35.81446 -7.66162  1.000 29.72721  ? 308 PHE A CD1 1 
ATOM   2646 C CD2 . PHE A 1 308 ? 5.33667   34.36958 -6.12289  1.000 29.37541  ? 308 PHE A CD2 1 
ATOM   2647 C CE1 . PHE A 1 308 ? 6.81790   34.72109 -8.42845  1.000 31.38443  ? 308 PHE A CE1 1 
ATOM   2648 C CE2 . PHE A 1 308 ? 5.71678   33.26638 -6.89022  1.000 30.09430  ? 308 PHE A CE2 1 
ATOM   2649 C CZ  . PHE A 1 308 ? 6.45265   33.45058 -8.03968  1.000 32.01844  ? 308 PHE A CZ  1 
ATOM   2650 N N   . ALA A 1 309 ? 6.65817   39.13740 -3.18663  1.000 37.85757  ? 309 ALA A N   1 
ATOM   2651 C CA  . ALA A 1 309 ? 6.13963   40.20343 -2.33499  1.000 40.34528  ? 309 ALA A CA  1 
ATOM   2652 C C   . ALA A 1 309 ? 5.98432   41.52420 -3.08720  1.000 45.77566  ? 309 ALA A C   1 
ATOM   2653 O O   . ALA A 1 309 ? 5.09134   42.32238 -2.76534  1.000 51.16766  ? 309 ALA A O   1 
ATOM   2654 C CB  . ALA A 1 309 ? 7.04658   40.39009 -1.11435  1.000 39.94368  ? 309 ALA A CB  1 
ATOM   2655 N N   . GLN A 1 310 ? 6.83541   41.79435 -4.07352  1.000 39.81824  ? 310 GLN A N   1 
ATOM   2656 C CA  . GLN A 1 310 ? 6.71698   43.09755 -4.71487  1.000 43.29013  ? 310 GLN A CA  1 
ATOM   2657 C C   . GLN A 1 310 ? 5.58301   43.15840 -5.73474  1.000 40.60781  ? 310 GLN A C   1 
ATOM   2658 O O   . GLN A 1 310 ? 5.20667   44.26355 -6.13619  1.000 41.39012  ? 310 GLN A O   1 
ATOM   2659 C CB  . GLN A 1 310 ? 8.05256   43.49918 -5.34845  1.000 49.01815  ? 310 GLN A CB  1 
ATOM   2660 C CG  . GLN A 1 310 ? 8.38934   42.85084 -6.65852  1.000 58.36075  ? 310 GLN A CG  1 
ATOM   2661 C CD  . GLN A 1 310 ? 9.47586   43.61449 -7.40337  1.000 70.30206  ? 310 GLN A CD  1 
ATOM   2662 O OE1 . GLN A 1 310 ? 10.60175  43.12685 -7.53943  1.000 71.14656  ? 310 GLN A OE1 1 
ATOM   2663 N NE2 . GLN A 1 310 ? 9.14901   44.81626 -7.88072  1.000 74.61162  ? 310 GLN A NE2 1 
ATOM   2664 N N   . TYR A 1 311 ? 5.00115   42.01472 -6.12705  1.000 38.55595  ? 311 TYR A N   1 
ATOM   2665 C CA  . TYR A 1 311 ? 3.89998   41.97882 -7.08937  1.000 37.01513  ? 311 TYR A CA  1 
ATOM   2666 C C   . TYR A 1 311 ? 2.57592   41.48508 -6.51194  1.000 35.04637  ? 311 TYR A C   1 
ATOM   2667 O O   . TYR A 1 311 ? 1.52110   41.82903 -7.05649  1.000 36.58367  ? 311 TYR A O   1 
ATOM   2668 C CB  . TYR A 1 311 ? 4.26265   41.09710 -8.30284  1.000 36.78327  ? 311 TYR A CB  1 
ATOM   2669 C CG  . TYR A 1 311 ? 5.47583   41.61507 -9.05805  1.000 36.66677  ? 311 TYR A CG  1 
ATOM   2670 C CD1 . TYR A 1 311 ? 5.38067   42.73681 -9.87698  1.000 39.60075  ? 311 TYR A CD1 1 
ATOM   2671 C CD2 . TYR A 1 311 ? 6.70689   40.98561 -8.95509  1.000 38.27060  ? 311 TYR A CD2 1 
ATOM   2672 C CE1 . TYR A 1 311 ? 6.48858   43.23854 -10.55265 1.000 40.17883  ? 311 TYR A CE1 1 
ATOM   2673 C CE2 . TYR A 1 311 ? 7.82352   41.47157 -9.63784  1.000 42.86370  ? 311 TYR A CE2 1 
ATOM   2674 C CZ  . TYR A 1 311 ? 7.70466   42.59957 -10.43106 1.000 43.97425  ? 311 TYR A CZ  1 
ATOM   2675 O OH  . TYR A 1 311 ? 8.79750   43.08107 -11.10114 1.000 47.83756  ? 311 TYR A OH  1 
ATOM   2676 N N   . HIS A 1 312 ? 2.60451   40.70865 -5.42810  1.000 33.31542  ? 312 HIS A N   1 
ATOM   2677 C CA  . HIS A 1 312 ? 1.40297   40.07140 -4.89579  1.000 33.09979  ? 312 HIS A CA  1 
ATOM   2678 C C   . HIS A 1 312 ? 0.37078   41.10611 -4.46263  1.000 35.62026  ? 312 HIS A C   1 
ATOM   2679 O O   . HIS A 1 312 ? 0.68825   42.06815 -3.74780  1.000 37.58162  ? 312 HIS A O   1 
ATOM   2680 C CB  . HIS A 1 312 ? 1.78605   39.16639 -3.71567  1.000 34.39247  ? 312 HIS A CB  1 
ATOM   2681 C CG  . HIS A 1 312 ? 0.62819   38.49104 -3.03557  1.000 34.40477  ? 312 HIS A CG  1 
ATOM   2682 N ND1 . HIS A 1 312 ? -0.38979  37.86147 -3.71887  1.000 34.14764  ? 312 HIS A ND1 1 
ATOM   2683 C CD2 . HIS A 1 312 ? 0.34622   38.33564 -1.71784  1.000 36.71879  ? 312 HIS A CD2 1 
ATOM   2684 C CE1 . HIS A 1 312 ? -1.25117  37.35083 -2.85510  1.000 35.42025  ? 312 HIS A CE1 1 
ATOM   2685 N NE2 . HIS A 1 312 ? -0.82850  37.62737 -1.63232  1.000 37.55856  ? 312 HIS A NE2 1 
ATOM   2686 N N   . ASP A 1 313 ? -0.86773  40.90252 -4.91143  1.000 33.12877  ? 313 ASP A N   1 
ATOM   2687 C CA  . ASP A 1 313 ? -1.99352  41.75895 -4.55035  1.000 34.65950  ? 313 ASP A CA  1 
ATOM   2688 C C   . ASP A 1 313 ? -3.21750  40.86291 -4.47442  1.000 34.85435  ? 313 ASP A C   1 
ATOM   2689 O O   . ASP A 1 313 ? -3.83571  40.56092 -5.50636  1.000 35.37317  ? 313 ASP A O   1 
ATOM   2690 C CB  . ASP A 1 313 ? -2.22572  42.88214 -5.55891  1.000 37.64814  ? 313 ASP A CB  1 
ATOM   2691 C CG  . ASP A 1 313 ? -3.31805  43.83504 -5.11152  1.000 43.66376  ? 313 ASP A CG  1 
ATOM   2692 O OD1 . ASP A 1 313 ? -4.10338  43.45610 -4.20868  1.000 44.83754  ? 313 ASP A OD1 1 
ATOM   2693 O OD2 . ASP A 1 313 ? -3.43193  44.93817 -5.69402  1.000 47.96084  ? 313 ASP A OD2 1 
ATOM   2694 N N   . PRO A 1 314 ? -3.62642  40.45409 -3.27413  1.000 37.60473  ? 314 PRO A N   1 
ATOM   2695 C CA  . PRO A 1 314 ? -4.75671  39.52408 -3.16180  1.000 36.34952  ? 314 PRO A CA  1 
ATOM   2696 C C   . PRO A 1 314 ? -6.06786  40.06783 -3.70961  1.000 38.45327  ? 314 PRO A C   1 
ATOM   2697 O O   . PRO A 1 314 ? -6.99739  39.27669 -3.90734  1.000 39.58882  ? 314 PRO A O   1 
ATOM   2698 C CB  . PRO A 1 314 ? -4.86292  39.27894 -1.64859  1.000 41.35687  ? 314 PRO A CB  1 
ATOM   2699 C CG  . PRO A 1 314 ? -3.67349  39.96201 -1.03677  1.000 44.71183  ? 314 PRO A CG  1 
ATOM   2700 C CD  . PRO A 1 314 ? -3.23720  41.00970 -1.97298  1.000 43.54109  ? 314 PRO A CD  1 
ATOM   2701 N N   . ASP A 1 315 ? -6.19439  41.37776 -3.93145  1.000 38.21875  ? 315 ASP A N   1 
ATOM   2702 C CA  . ASP A 1 315 ? -7.40526  41.94620 -4.50845  1.000 40.37577  ? 315 ASP A CA  1 
ATOM   2703 C C   . ASP A 1 315 ? -7.32469  42.11411 -6.01532  1.000 38.07010  ? 315 ASP A C   1 
ATOM   2704 O O   . ASP A 1 315 ? -8.24897  42.67642 -6.60695  1.000 38.10018  ? 315 ASP A O   1 
ATOM   2705 C CB  . ASP A 1 315 ? -7.72637  43.30450 -3.87665  1.000 43.98258  ? 315 ASP A CB  1 
ATOM   2706 C CG  . ASP A 1 315 ? -8.03155  43.19862 -2.40577  1.000 51.52365  ? 315 ASP A CG  1 
ATOM   2707 O OD1 . ASP A 1 315 ? -8.78464  42.27202 -2.03263  1.000 49.20332  ? 315 ASP A OD1 1 
ATOM   2708 O OD2 . ASP A 1 315 ? -7.54111  44.05233 -1.62965  1.000 57.81835  ? 315 ASP A OD2 1 
ATOM   2709 N N   . ASP A 1 316 ? -6.24675  41.65621 -6.64213  1.000 35.23943  ? 316 ASP A N   1 
ATOM   2710 C CA  . ASP A 1 316 ? -6.06066  41.73586 -8.08631  1.000 37.18232  ? 316 ASP A CA  1 
ATOM   2711 C C   . ASP A 1 316 ? -5.53378  40.42367 -8.64026  1.000 33.72992  ? 316 ASP A C   1 
ATOM   2712 O O   . ASP A 1 316 ? -4.71705  40.41051 -9.56318  1.000 36.32595  ? 316 ASP A O   1 
ATOM   2713 C CB  . ASP A 1 316 ? -5.12619  42.88007 -8.46244  1.000 44.65286  ? 316 ASP A CB  1 
ATOM   2714 C CG  . ASP A 1 316 ? -5.23405  43.25099 -9.92960  1.000 55.24484  ? 316 ASP A CG  1 
ATOM   2715 O OD1 . ASP A 1 316 ? -6.27838  42.94407 -10.54645 1.000 56.71393  ? 316 ASP A OD1 1 
ATOM   2716 O OD2 . ASP A 1 316 ? -4.26365  43.82166 -10.47244 1.000 60.20195  ? 316 ASP A OD2 1 
ATOM   2717 N N   . GLU A 1 317 ? -5.99517  39.30354 -8.07889  1.000 33.98628  ? 317 GLU A N   1 
ATOM   2718 C CA  . GLU A 1 317 ? -5.66631  37.95199 -8.54748  1.000 32.44969  ? 317 GLU A CA  1 
ATOM   2719 C C   . GLU A 1 317 ? -6.96857  37.17199 -8.67860  1.000 34.98022  ? 317 GLU A C   1 
ATOM   2720 O O   . GLU A 1 317 ? -7.28578  36.30139 -7.85253  1.000 32.14520  ? 317 GLU A O   1 
ATOM   2721 C CB  . GLU A 1 317 ? -4.67743  37.28036 -7.59519  1.000 33.06700  ? 317 GLU A CB  1 
ATOM   2722 C CG  . GLU A 1 317 ? -3.37364  38.10543 -7.52429  1.000 33.94279  ? 317 GLU A CG  1 
ATOM   2723 C CD  . GLU A 1 317 ? -2.42185  37.77211 -6.37900  1.000 36.50883  ? 317 GLU A CD  1 
ATOM   2724 O OE1 . GLU A 1 317 ? -2.79680  37.04495 -5.43007  1.000 37.90358  ? 317 GLU A OE1 1 
ATOM   2725 O OE2 . GLU A 1 317 ? -1.29342  38.31127 -6.41021  1.000 36.07778  ? 317 GLU A OE2 1 
ATOM   2726 N N   . PRO A 1 318 ? -7.76003  37.48286 -9.70258  1.000 32.31530  ? 318 PRO A N   1 
ATOM   2727 C CA  . PRO A 1 318 ? -9.15087  37.02731 -9.73880  1.000 34.64116  ? 318 PRO A CA  1 
ATOM   2728 C C   . PRO A 1 318 ? -9.28565  35.56277 -10.13871 1.000 32.49560  ? 318 PRO A C   1 
ATOM   2729 O O   . PRO A 1 318 ? -8.38880  34.94801 -10.72298 1.000 32.31902  ? 318 PRO A O   1 
ATOM   2730 C CB  . PRO A 1 318 ? -9.78759  37.94521 -10.78993 1.000 37.99559  ? 318 PRO A CB  1 
ATOM   2731 C CG  . PRO A 1 318 ? -8.64889  38.30026 -11.70965 1.000 34.01954  ? 318 PRO A CG  1 
ATOM   2732 C CD  . PRO A 1 318 ? -7.44956  38.41818 -10.79811 1.000 31.75493  ? 318 PRO A CD  1 
ATOM   2733 N N   . VAL A 1 319 ? -10.44739 35.01037 -9.80383  1.000 32.15666  ? 319 VAL A N   1 
ATOM   2734 C CA  . VAL A 1 319 ? -10.80119 33.64207 -10.14339 1.000 31.58408  ? 319 VAL A CA  1 
ATOM   2735 C C   . VAL A 1 319 ? -11.83482 33.66740 -11.26867 1.000 27.81565  ? 319 VAL A C   1 
ATOM   2736 O O   . VAL A 1 319 ? -12.40103 34.70992 -11.60787 1.000 32.51131  ? 319 VAL A O   1 
ATOM   2737 C CB  . VAL A 1 319 ? -11.33120 32.86747 -8.92270  1.000 34.93745  ? 319 VAL A CB  1 
ATOM   2738 C CG1 . VAL A 1 319 ? -10.22187 32.67478 -7.88160  1.000 39.31317  ? 319 VAL A CG1 1 
ATOM   2739 C CG2 . VAL A 1 319 ? -12.53619 33.59496 -8.32179  1.000 38.23012  ? 319 VAL A CG2 1 
ATOM   2740 N N   . ALA A 1 320 ? -12.08751 32.49859 -11.83902 1.000 31.97039  ? 320 ALA A N   1 
ATOM   2741 C CA  . ALA A 1 320 ? -12.94112 32.36060 -13.01860 1.000 30.40178  ? 320 ALA A CA  1 
ATOM   2742 C C   . ALA A 1 320 ? -14.40554 32.11191 -12.64574 1.000 27.77669  ? 320 ALA A C   1 
ATOM   2743 O O   . ALA A 1 320 ? -14.71855 31.60605 -11.56365 1.000 31.11105  ? 320 ALA A O   1 
ATOM   2744 C CB  . ALA A 1 320 ? -12.43729 31.20452 -13.88871 1.000 30.11971  ? 320 ALA A CB  1 
ATOM   2745 N N   . ASP A 1 321 ? -15.31114 32.49056 -13.55927 1.000 27.80997  ? 321 ASP A N   1 
ATOM   2746 C CA  . ASP A 1 321 ? -16.69415 32.04210 -13.45419 1.000 27.70664  ? 321 ASP A CA  1 
ATOM   2747 C C   . ASP A 1 321 ? -16.75399 30.52063 -13.52455 1.000 31.30229  ? 321 ASP A C   1 
ATOM   2748 O O   . ASP A 1 321 ? -15.87341 29.88159 -14.10997 1.000 31.58090  ? 321 ASP A O   1 
ATOM   2749 C CB  . ASP A 1 321 ? -17.54730 32.62148 -14.57680 1.000 30.39701  ? 321 ASP A CB  1 
ATOM   2750 C CG  . ASP A 1 321 ? -17.79875 34.09475 -14.41237 1.000 38.42738  ? 321 ASP A CG  1 
ATOM   2751 O OD1 . ASP A 1 321 ? -17.60170 34.59717 -13.29403 1.000 39.76388  ? 321 ASP A OD1 1 
ATOM   2752 O OD2 . ASP A 1 321 ? -18.19674 34.75236 -15.39489 1.000 46.05457  ? 321 ASP A OD2 1 
ATOM   2753 N N   . PRO A 1 322 ? -17.79706 29.92111 -12.94445 1.000 31.50156  ? 322 PRO A N   1 
ATOM   2754 C CA  . PRO A 1 322 ? -17.94153 28.46292 -13.01986 1.000 32.30786  ? 322 PRO A CA  1 
ATOM   2755 C C   . PRO A 1 322 ? -17.93603 28.00395 -14.46888 1.000 32.16625  ? 322 PRO A C   1 
ATOM   2756 O O   . PRO A 1 322 ? -18.47472 28.67398 -15.35270 1.000 34.17467  ? 322 PRO A O   1 
ATOM   2757 C CB  . PRO A 1 322 ? -19.29690 28.20487 -12.36132 1.000 33.30634  ? 322 PRO A CB  1 
ATOM   2758 C CG  . PRO A 1 322 ? -19.52253 29.42434 -11.48002 1.000 35.98449  ? 322 PRO A CG  1 
ATOM   2759 C CD  . PRO A 1 322 ? -18.92117 30.55963 -12.24157 1.000 33.30233  ? 322 PRO A CD  1 
ATOM   2760 N N   . TYR A 1 323 ? -17.32966 26.84244 -14.70871 1.000 32.23578  ? 323 TYR A N   1 
ATOM   2761 C CA  . TYR A 1 323 ? -17.14781 26.31750 -16.06007 1.000 29.66910  ? 323 TYR A CA  1 
ATOM   2762 C C   . TYR A 1 323 ? -17.74727 24.91362 -16.09796 1.000 32.82959  ? 323 TYR A C   1 
ATOM   2763 O O   . TYR A 1 323 ? -17.24741 24.00348 -15.43222 1.000 33.83363  ? 323 TYR A O   1 
ATOM   2764 C CB  . TYR A 1 323 ? -15.66522 26.30630 -16.44373 1.000 29.67187  ? 323 TYR A CB  1 
ATOM   2765 C CG  . TYR A 1 323 ? -15.40188 25.71673 -17.80682 1.000 32.30464  ? 323 TYR A CG  1 
ATOM   2766 C CD1 . TYR A 1 323 ? -15.90754 26.31143 -18.95399 1.000 38.59842  ? 323 TYR A CD1 1 
ATOM   2767 C CD2 . TYR A 1 323 ? -14.64987 24.56965 -17.94712 1.000 33.32144  ? 323 TYR A CD2 1 
ATOM   2768 C CE1 . TYR A 1 323 ? -15.64358 25.77379 -20.20548 1.000 41.64173  ? 323 TYR A CE1 1 
ATOM   2769 C CE2 . TYR A 1 323 ? -14.38200 24.03121 -19.19307 1.000 39.18599  ? 323 TYR A CE2 1 
ATOM   2770 C CZ  . TYR A 1 323 ? -14.87820 24.62817 -20.31128 1.000 43.39416  ? 323 TYR A CZ  1 
ATOM   2771 O OH  . TYR A 1 323 ? -14.61571 24.07954 -21.55155 1.000 49.03275  ? 323 TYR A OH  1 
ATOM   2772 N N   . ASP A 1 324 ? -18.81797 24.73537 -16.86774 1.000 30.99958  ? 324 ASP A N   1 
ATOM   2773 C CA  . ASP A 1 324 ? -19.56356 23.48245 -16.87374 1.000 31.09444  ? 324 ASP A CA  1 
ATOM   2774 C C   . ASP A 1 324 ? -18.91782 22.54412 -17.88318 1.000 31.99956  ? 324 ASP A C   1 
ATOM   2775 O O   . ASP A 1 324 ? -18.97406 22.78487 -19.09281 1.000 33.64190  ? 324 ASP A O   1 
ATOM   2776 C CB  . ASP A 1 324 ? -21.03812 23.75690 -17.16682 1.000 32.39568  ? 324 ASP A CB  1 
ATOM   2777 C CG  . ASP A 1 324 ? -21.87625 22.49496 -17.33286 1.000 34.37289  ? 324 ASP A CG  1 
ATOM   2778 O OD1 . ASP A 1 324 ? -21.34110 21.39811 -17.58568 1.000 36.39258  ? 324 ASP A OD1 1 
ATOM   2779 O OD2 . ASP A 1 324 ? -23.10542 22.60088 -17.07556 1.000 37.78415  ? 324 ASP A OD2 1 
ATOM   2780 N N   . GLN A 1 325 ? -18.27327 21.48865 -17.38303 1.000 32.84377  ? 325 GLN A N   1 
ATOM   2781 C CA  . GLN A 1 325 ? -17.58820 20.52259 -18.22982 1.000 32.14276  ? 325 GLN A CA  1 
ATOM   2782 C C   . GLN A 1 325 ? -18.32790 19.20313 -18.32254 1.000 36.30727  ? 325 GLN A C   1 
ATOM   2783 O O   . GLN A 1 325 ? -17.71581 18.17650 -18.64070 1.000 36.69546  ? 325 GLN A O   1 
ATOM   2784 C CB  . GLN A 1 325 ? -16.17246 20.25720 -17.72943 1.000 38.47181  ? 325 GLN A CB  1 
ATOM   2785 C CG  . GLN A 1 325 ? -15.24893 21.39448 -17.85234 1.000 44.68511  ? 325 GLN A CG  1 
ATOM   2786 C CD  . GLN A 1 325 ? -13.86153 20.96447 -17.48015 1.000 47.85312  ? 325 GLN A CD  1 
ATOM   2787 O OE1 . GLN A 1 325 ? -13.23034 20.20538 -18.22046 1.000 46.25859  ? 325 GLN A OE1 1 
ATOM   2788 N NE2 . GLN A 1 325 ? -13.38552 21.40689 -16.32015 1.000 44.50445  ? 325 GLN A NE2 1 
ATOM   2789 N N   . SER A 1 326 ? -19.62563 19.19752 -18.03732 1.000 32.53721  ? 326 SER A N   1 
ATOM   2790 C CA  . SER A 1 326 ? -20.34331 17.93033 -18.05185 1.000 34.07652  ? 326 SER A CA  1 
ATOM   2791 C C   . SER A 1 326 ? -20.27584 17.27923 -19.42361 1.000 32.22863  ? 326 SER A C   1 
ATOM   2792 O O   . SER A 1 326 ? -20.39265 16.05440 -19.52882 1.000 33.03388  ? 326 SER A O   1 
ATOM   2793 C CB  . SER A 1 326 ? -21.79762 18.12849 -17.62191 1.000 35.69117  ? 326 SER A CB  1 
ATOM   2794 O OG  . SER A 1 326 ? -22.48617 18.99385 -18.50639 1.000 37.10364  ? 326 SER A OG  1 
ATOM   2795 N N   . PHE A 1 327 ? -20.08828 18.07463 -20.48343 1.000 32.60175  ? 327 PHE A N   1 
ATOM   2796 C CA  . PHE A 1 327 ? -20.03530 17.51130 -21.82833 1.000 30.52793  ? 327 PHE A CA  1 
ATOM   2797 C C   . PHE A 1 327 ? -18.88961 16.52335 -21.98938 1.000 29.71050  ? 327 PHE A C   1 
ATOM   2798 O O   . PHE A 1 327 ? -18.93870 15.66782 -22.88011 1.000 35.70259  ? 327 PHE A O   1 
ATOM   2799 C CB  . PHE A 1 327 ? -19.92174 18.62533 -22.88478 1.000 30.47602  ? 327 PHE A CB  1 
ATOM   2800 C CG  . PHE A 1 327 ? -18.54585 19.26207 -22.96448 1.000 32.29357  ? 327 PHE A CG  1 
ATOM   2801 C CD1 . PHE A 1 327 ? -17.57593 18.74386 -23.81307 1.000 33.01215  ? 327 PHE A CD1 1 
ATOM   2802 C CD2 . PHE A 1 327 ? -18.23930 20.38957 -22.21672 1.000 33.90190  ? 327 PHE A CD2 1 
ATOM   2803 C CE1 . PHE A 1 327 ? -16.30684 19.31423 -23.89091 1.000 33.65840  ? 327 PHE A CE1 1 
ATOM   2804 C CE2 . PHE A 1 327 ? -16.97163 20.98687 -22.29930 1.000 32.61634  ? 327 PHE A CE2 1 
ATOM   2805 C CZ  . PHE A 1 327 ? -16.00592 20.44794 -23.14468 1.000 32.81569  ? 327 PHE A CZ  1 
ATOM   2806 N N   . GLU A 1 328 ? -17.87278 16.59884 -21.13525 1.000 30.38431  ? 328 GLU A N   1 
ATOM   2807 C CA  . GLU A 1 328 ? -16.72811 15.71457 -21.30879 1.000 33.94295  ? 328 GLU A CA  1 
ATOM   2808 C C   . GLU A 1 328 ? -17.11441 14.25431 -21.09847 1.000 36.41303  ? 328 GLU A C   1 
ATOM   2809 O O   . GLU A 1 328 ? -16.53884 13.36979 -21.74220 1.000 37.86206  ? 328 GLU A O   1 
ATOM   2810 C CB  . GLU A 1 328 ? -15.60177 16.13468 -20.36537 1.000 34.43935  ? 328 GLU A CB  1 
ATOM   2811 C CG  . GLU A 1 328 ? -15.00465 17.49115 -20.72490 1.000 36.20076  ? 328 GLU A CG  1 
ATOM   2812 C CD  . GLU A 1 328 ? -14.04749 17.41473 -21.91705 1.000 40.21520  ? 328 GLU A CD  1 
ATOM   2813 O OE1 . GLU A 1 328 ? -14.03070 16.37396 -22.63093 1.000 40.97653  ? 328 GLU A OE1 1 
ATOM   2814 O OE2 . GLU A 1 328 ? -13.32018 18.40958 -22.14972 1.000 39.05539  ? 328 GLU A OE2 1 
ATOM   2815 N N   . SER A 1 329 ? -18.09037 13.99327 -20.22192 1.000 38.32893  ? 329 SER A N   1 
ATOM   2816 C CA  . SER A 1 329 ? -18.62877 12.66407 -19.93358 1.000 43.91026  ? 329 SER A CA  1 
ATOM   2817 C C   . SER A 1 329 ? -19.71007 12.22699 -20.90710 1.000 44.24124  ? 329 SER A C   1 
ATOM   2818 O O   . SER A 1 329 ? -20.24238 11.12044 -20.75683 1.000 47.82498  ? 329 SER A O   1 
ATOM   2819 C CB  . SER A 1 329 ? -19.23312 12.63227 -18.53021 1.000 52.68817  ? 329 SER A CB  1 
ATOM   2820 O OG  . SER A 1 329 ? -18.42847 13.34307 -17.62013 1.000 64.57460  ? 329 SER A OG  1 
ATOM   2821 N N   . ARG A 1 330 ? -20.07417 13.07422 -21.86374 1.000 43.27052  ? 330 ARG A N   1 
ATOM   2822 C CA  . ARG A 1 330 ? -21.18042 12.80906 -22.77791 1.000 46.13295  ? 330 ARG A CA  1 
ATOM   2823 C C   . ARG A 1 330 ? -20.72248 12.09163 -24.03352 1.000 45.60119  ? 330 ARG A C   1 
ATOM   2824 O O   . ARG A 1 330 ? -19.68235 12.41674 -24.61214 1.000 47.52666  ? 330 ARG A O   1 
ATOM   2825 C CB  . ARG A 1 330 ? -21.87468 14.10424 -23.20127 1.000 43.69444  ? 330 ARG A CB  1 
ATOM   2826 C CG  . ARG A 1 330 ? -23.35475 14.11209 -23.13911 1.000 43.15634  ? 330 ARG A CG  1 
ATOM   2827 C CD  . ARG A 1 330 ? -23.87041 15.47952 -23.54223 1.000 42.41931  ? 330 ARG A CD  1 
ATOM   2828 N NE  . ARG A 1 330 ? -24.03688 16.27620 -22.33879 1.000 42.00613  ? 330 ARG A NE  1 
ATOM   2829 C CZ  . ARG A 1 330 ? -23.73775 17.56196 -22.23710 1.000 38.98183  ? 330 ARG A CZ  1 
ATOM   2830 N NH1 . ARG A 1 330 ? -23.42799 18.29195 -23.30719 1.000 38.01082  ? 330 ARG A NH1 1 
ATOM   2831 N NH2 . ARG A 1 330 ? -23.72730 18.12382 -21.03160 1.000 35.90654  ? 330 ARG A NH2 1 
ATOM   2832 N N   . ASP A 1 331 ? -21.53737 11.15239 -24.47577 1.000 42.59087  ? 331 ASP A N   1 
ATOM   2833 C CA  . ASP A 1 331 ? -21.35215 10.47969 -25.75088 1.000 42.08378  ? 331 ASP A CA  1 
ATOM   2834 C C   . ASP A 1 331 ? -22.42446 11.00241 -26.69783 1.000 39.96903  ? 331 ASP A C   1 
ATOM   2835 O O   . ASP A 1 331 ? -23.62271 10.81569 -26.44748 1.000 42.38269  ? 331 ASP A O   1 
ATOM   2836 C CB  . ASP A 1 331 ? -21.43724 8.96991  -25.55223 1.000 50.30931  ? 331 ASP A CB  1 
ATOM   2837 C CG  . ASP A 1 331 ? -20.25127 8.43450  -24.76920 1.000 64.58425  ? 331 ASP A CG  1 
ATOM   2838 O OD1 . ASP A 1 331 ? -20.44267 7.57736  -23.88460 1.000 68.26434  ? 331 ASP A OD1 1 
ATOM   2839 O OD2 . ASP A 1 331 ? -19.11776 8.88358  -25.03767 1.000 69.63611  ? 331 ASP A OD2 1 
ATOM   2840 N N   . LEU A 1 332 ? -22.00192 11.69263 -27.75734 1.000 38.62113  ? 332 LEU A N   1 
ATOM   2841 C CA  . LEU A 1 332 ? -22.91761 12.20412 -28.77005 1.000 35.97155  ? 332 LEU A CA  1 
ATOM   2842 C C   . LEU A 1 332 ? -22.44629 11.78389 -30.15675 1.000 37.69027  ? 332 LEU A C   1 
ATOM   2843 O O   . LEU A 1 332 ? -21.30988 11.33461 -30.34418 1.000 39.91846  ? 332 LEU A O   1 
ATOM   2844 C CB  . LEU A 1 332 ? -23.05043 13.73419 -28.71034 1.000 33.90320  ? 332 LEU A CB  1 
ATOM   2845 C CG  . LEU A 1 332 ? -23.61471 14.29553 -27.39575 1.000 30.51193  ? 332 LEU A CG  1 
ATOM   2846 C CD1 . LEU A 1 332 ? -23.49262 15.83048 -27.32334 1.000 32.89718  ? 332 LEU A CD1 1 
ATOM   2847 C CD2 . LEU A 1 332 ? -25.07785 13.81685 -27.16977 1.000 32.31863  ? 332 LEU A CD2 1 
ATOM   2848 N N   . LEU A 1 333 ? -23.33614 11.94955 -31.13753 1.000 35.34567  ? 333 LEU A N   1 
ATOM   2849 C CA  . LEU A 1 333 ? -23.00310 11.75367 -32.54558 1.000 36.19602  ? 333 LEU A CA  1 
ATOM   2850 C C   . LEU A 1 333 ? -22.34263 13.00516 -33.12733 1.000 36.43231  ? 333 LEU A C   1 
ATOM   2851 O O   . LEU A 1 333 ? -22.44796 14.10677 -32.57937 1.000 40.24040  ? 333 LEU A O   1 
ATOM   2852 C CB  . LEU A 1 333 ? -24.25643 11.43092 -33.36084 1.000 38.31850  ? 333 LEU A CB  1 
ATOM   2853 C CG  . LEU A 1 333 ? -25.11503 10.25931 -32.89452 1.000 43.45096  ? 333 LEU A CG  1 
ATOM   2854 C CD1 . LEU A 1 333 ? -26.53457 10.31649 -33.49161 1.000 45.97324  ? 333 LEU A CD1 1 
ATOM   2855 C CD2 . LEU A 1 333 ? -24.41652 8.97411  -33.26226 1.000 47.17932  ? 333 LEU A CD2 1 
ATOM   2856 N N   . ILE A 1 334 ? -21.68189 12.82666 -34.27732 1.000 38.61493  ? 334 ILE A N   1 
ATOM   2857 C CA  . ILE A 1 334 ? -20.97300 13.93984 -34.92155 1.000 40.37198  ? 334 ILE A CA  1 
ATOM   2858 C C   . ILE A 1 334 ? -21.89517 15.14211 -35.08608 1.000 39.20028  ? 334 ILE A C   1 
ATOM   2859 O O   . ILE A 1 334 ? -21.55530 16.27470 -34.71901 1.000 40.47052  ? 334 ILE A O   1 
ATOM   2860 C CB  . ILE A 1 334 ? -20.40697 13.50483 -36.28402 1.000 44.50788  ? 334 ILE A CB  1 
ATOM   2861 C CG1 . ILE A 1 334 ? -19.25529 12.52658 -36.11137 1.000 48.89500  ? 334 ILE A CG1 1 
ATOM   2862 C CG2 . ILE A 1 334 ? -19.94627 14.72326 -37.06662 1.000 45.54994  ? 334 ILE A CG2 1 
ATOM   2863 C CD1 . ILE A 1 334 ? -18.57826 12.16881 -37.43875 1.000 49.24335  ? 334 ILE A CD1 1 
ATOM   2864 N N   . ASP A 1 335 ? -23.07476 14.90806 -35.66011 1.000 39.63948  ? 335 ASP A N   1 
ATOM   2865 C CA  . ASP A 1 335 ? -24.00647 15.98526 -35.97082 1.000 41.36134  ? 335 ASP A CA  1 
ATOM   2866 C C   . ASP A 1 335 ? -24.49545 16.70132 -34.71698 1.000 39.37212  ? 335 ASP A C   1 
ATOM   2867 O O   . ASP A 1 335 ? -24.84761 17.88654 -34.78271 1.000 38.74430  ? 335 ASP A O   1 
ATOM   2868 C CB  . ASP A 1 335 ? -25.18471 15.41145 -36.75833 1.000 50.84205  ? 335 ASP A CB  1 
ATOM   2869 C CG  . ASP A 1 335 ? -24.91719 15.37282 -38.25180 1.000 61.60534  ? 335 ASP A CG  1 
ATOM   2870 O OD1 . ASP A 1 335 ? -23.76613 15.65396 -38.65116 1.000 61.75910  ? 335 ASP A OD1 1 
ATOM   2871 O OD2 . ASP A 1 335 ? -25.83958 15.02541 -39.02123 1.000 66.26050  ? 335 ASP A OD2 1 
ATOM   2872 N N   . GLU A 1 336 ? -24.51204 16.01515 -33.57297 1.000 34.67175  ? 336 GLU A N   1 
ATOM   2873 C CA  . GLU A 1 336 ? -24.90645 16.65433 -32.32327 1.000 34.45340  ? 336 GLU A CA  1 
ATOM   2874 C C   . GLU A 1 336 ? -23.79085 17.52955 -31.76741 1.000 35.01406  ? 336 GLU A C   1 
ATOM   2875 O O   . GLU A 1 336 ? -24.06720 18.64058 -31.31085 1.000 34.30382  ? 336 GLU A O   1 
ATOM   2876 C CB  . GLU A 1 336 ? -25.35960 15.58385 -31.33442 1.000 37.21459  ? 336 GLU A CB  1 
ATOM   2877 C CG  . GLU A 1 336 ? -26.49230 14.74781 -31.93227 1.000 38.61310  ? 336 GLU A CG  1 
ATOM   2878 C CD  . GLU A 1 336 ? -26.96666 13.63801 -31.02757 1.000 40.46589  ? 336 GLU A CD  1 
ATOM   2879 O OE1 . GLU A 1 336 ? -26.09591 12.86062 -30.57367 1.000 38.57377  ? 336 GLU A OE1 1 
ATOM   2880 O OE2 . GLU A 1 336 ? -28.19926 13.47750 -30.83508 1.000 40.69725  ? 336 GLU A OE2 1 
ATOM   2881 N N   . TRP A 1 337 ? -22.53111 17.05844 -31.79630 1.000 35.34143  ? 337 TRP A N   1 
ATOM   2882 C CA  . TRP A 1 337 ? -21.40602 17.93095 -31.44974 1.000 33.59335  ? 337 TRP A CA  1 
ATOM   2883 C C   . TRP A 1 337 ? -21.36417 19.13432 -32.37193 1.000 32.85667  ? 337 TRP A C   1 
ATOM   2884 O O   . TRP A 1 337 ? -21.04527 20.25445 -31.95150 1.000 29.42207  ? 337 TRP A O   1 
ATOM   2885 C CB  . TRP A 1 337 ? -20.07894 17.16432 -31.53632 1.000 33.97772  ? 337 TRP A CB  1 
ATOM   2886 C CG  . TRP A 1 337 ? -19.89828 16.13692 -30.44706 1.000 30.92885  ? 337 TRP A CG  1 
ATOM   2887 C CD1 . TRP A 1 337 ? -19.71456 14.79543 -30.60423 1.000 30.66755  ? 337 TRP A CD1 1 
ATOM   2888 C CD2 . TRP A 1 337 ? -19.85831 16.38766 -29.03446 1.000 30.52686  ? 337 TRP A CD2 1 
ATOM   2889 N NE1 . TRP A 1 337 ? -19.59137 14.19025 -29.37098 1.000 31.21495  ? 337 TRP A NE1 1 
ATOM   2890 C CE2 . TRP A 1 337 ? -19.67094 15.14787 -28.39324 1.000 31.11046  ? 337 TRP A CE2 1 
ATOM   2891 C CE3 . TRP A 1 337 ? -19.98156 17.54115 -28.25334 1.000 33.05944  ? 337 TRP A CE3 1 
ATOM   2892 C CZ2 . TRP A 1 337 ? -19.59410 15.02575 -27.00110 1.000 32.78283  ? 337 TRP A CZ2 1 
ATOM   2893 C CZ3 . TRP A 1 337 ? -19.89910 17.43038 -26.87328 1.000 32.69766  ? 337 TRP A CZ3 1 
ATOM   2894 C CH2 . TRP A 1 337 ? -19.71789 16.17050 -26.25580 1.000 31.63506  ? 337 TRP A CH2 1 
ATOM   2895 N N   . LYS A 1 338 ? -21.67867 18.91185 -33.64146 1.000 31.50164  ? 338 LYS A N   1 
ATOM   2896 C CA  . LYS A 1 338 ? -21.64193 19.98779 -34.61713 1.000 35.09757  ? 338 LYS A CA  1 
ATOM   2897 C C   . LYS A 1 338 ? -22.69966 21.03606 -34.31025 1.000 33.41486  ? 338 LYS A C   1 
ATOM   2898 O O   . LYS A 1 338 ? -22.43050 22.24056 -34.38198 1.000 35.12864  ? 338 LYS A O   1 
ATOM   2899 C CB  . LYS A 1 338 ? -21.83287 19.39343 -36.01057 1.000 38.78352  ? 338 LYS A CB  1 
ATOM   2900 C CG  . LYS A 1 338 ? -21.59593 20.32309 -37.15064 1.000 42.83401  ? 338 LYS A CG  1 
ATOM   2901 C CD  . LYS A 1 338 ? -21.58301 19.51137 -38.44723 1.000 44.69249  ? 338 LYS A CD  1 
ATOM   2902 C CE  . LYS A 1 338 ? -21.93665 20.36046 -39.64454 1.000 49.78072  ? 338 LYS A CE  1 
ATOM   2903 N NZ  . LYS A 1 338 ? -21.49263 19.73400 -40.93052 1.000 49.91494  ? 338 LYS A NZ  1 
ATOM   2904 N N   . SER A 1 339 ? -23.90708 20.60220 -33.95142 1.000 34.68130  ? 339 SER A N   1 
ATOM   2905 C CA  . SER A 1 339 ? -24.94997 21.57488 -33.64545 1.000 37.85073  ? 339 SER A CA  1 
ATOM   2906 C C   . SER A 1 339 ? -24.63432 22.31618 -32.34434 1.000 35.91378  ? 339 SER A C   1 
ATOM   2907 O O   . SER A 1 339 ? -24.86760 23.52856 -32.23980 1.000 33.88231  ? 339 SER A O   1 
ATOM   2908 C CB  . SER A 1 339 ? -26.30680 20.86775 -33.59334 1.000 39.25535  ? 339 SER A CB  1 
ATOM   2909 O OG  . SER A 1 339 ? -27.33717 21.69179 -33.06312 1.000 40.56145  ? 339 SER A OG  1 
ATOM   2910 N N   . LEU A 1 340 ? -24.06217 21.61805 -31.35864 1.000 32.93264  ? 340 LEU A N   1 
ATOM   2911 C CA  . LEU A 1 340 ? -23.60807 22.30111 -30.14472 1.000 32.46122  ? 340 LEU A CA  1 
ATOM   2912 C C   . LEU A 1 340 ? -22.57863 23.36842 -30.47738 1.000 32.33833  ? 340 LEU A C   1 
ATOM   2913 O O   . LEU A 1 340 ? -22.61091 24.48025 -29.93101 1.000 29.84924  ? 340 LEU A O   1 
ATOM   2914 C CB  . LEU A 1 340 ? -23.02573 21.29432 -29.15253 1.000 30.21006  ? 340 LEU A CB  1 
ATOM   2915 C CG  . LEU A 1 340 ? -24.05481 20.37751 -28.46973 1.000 33.09353  ? 340 LEU A CG  1 
ATOM   2916 C CD1 . LEU A 1 340 ? -23.38067 19.47921 -27.47273 1.000 33.92810  ? 340 LEU A CD1 1 
ATOM   2917 C CD2 . LEU A 1 340 ? -25.14290 21.19831 -27.78137 1.000 39.50741  ? 340 LEU A CD2 1 
ATOM   2918 N N   . THR A 1 341 ? -21.63025 23.02912 -31.34265 1.000 30.46125  ? 341 THR A N   1 
ATOM   2919 C CA  . THR A 1 341 ? -20.60857 23.99051 -31.74926 1.000 29.71465  ? 341 THR A CA  1 
ATOM   2920 C C   . THR A 1 341 ? -21.23352 25.18190 -32.46774 1.000 31.19107  ? 341 THR A C   1 
ATOM   2921 O O   . THR A 1 341 ? -20.92201 26.34041 -32.16737 1.000 32.89861  ? 341 THR A O   1 
ATOM   2922 C CB  . THR A 1 341 ? -19.57767 23.28713 -32.63424 1.000 30.80984  ? 341 THR A CB  1 
ATOM   2923 O OG1 . THR A 1 341 ? -18.96474 22.22469 -31.88437 1.000 32.88395  ? 341 THR A OG1 1 
ATOM   2924 C CG2 . THR A 1 341 ? -18.49448 24.26380 -33.09177 1.000 32.01115  ? 341 THR A CG2 1 
ATOM   2925 N N   . TYR A 1 342 ? -22.13260 24.91488 -33.41332 1.000 31.66441  ? 342 TYR A N   1 
ATOM   2926 C CA  . TYR A 1 342 ? -22.79721 25.99471 -34.13886 1.000 32.92974  ? 342 TYR A CA  1 
ATOM   2927 C C   . TYR A 1 342 ? -23.49729 26.95247 -33.17896 1.000 35.62286  ? 342 TYR A C   1 
ATOM   2928 O O   . TYR A 1 342 ? -23.39328 28.17906 -33.31739 1.000 37.74415  ? 342 TYR A O   1 
ATOM   2929 C CB  . TYR A 1 342 ? -23.78091 25.40383 -35.15440 1.000 32.13222  ? 342 TYR A CB  1 
ATOM   2930 C CG  . TYR A 1 342 ? -24.45375 26.41856 -36.05692 1.000 34.77492  ? 342 TYR A CG  1 
ATOM   2931 C CD1 . TYR A 1 342 ? -23.74372 27.05623 -37.06661 1.000 33.73500  ? 342 TYR A CD1 1 
ATOM   2932 C CD2 . TYR A 1 342 ? -25.80219 26.73127 -35.90622 1.000 36.19305  ? 342 TYR A CD2 1 
ATOM   2933 C CE1 . TYR A 1 342 ? -24.34838 27.98397 -37.89894 1.000 37.41712  ? 342 TYR A CE1 1 
ATOM   2934 C CE2 . TYR A 1 342 ? -26.42495 27.65989 -36.74613 1.000 39.47709  ? 342 TYR A CE2 1 
ATOM   2935 C CZ  . TYR A 1 342 ? -25.68771 28.28084 -37.73886 1.000 38.51872  ? 342 TYR A CZ  1 
ATOM   2936 O OH  . TYR A 1 342 ? -26.26831 29.21101 -38.58348 1.000 40.52421  ? 342 TYR A OH  1 
ATOM   2937 N N   . ASP A 1 343 ? -24.21721 26.40990 -32.19585 1.000 32.53404  ? 343 ASP A N   1 
ATOM   2938 C CA  . ASP A 1 343 ? -24.87037 27.25792 -31.20689 1.000 33.61553  ? 343 ASP A CA  1 
ATOM   2939 C C   . ASP A 1 343 ? -23.86781 28.18138 -30.53103 1.000 34.91257  ? 343 ASP A C   1 
ATOM   2940 O O   . ASP A 1 343 ? -24.15000 29.36878 -30.31722 1.000 33.52855  ? 343 ASP A O   1 
ATOM   2941 C CB  . ASP A 1 343 ? -25.57279 26.40557 -30.14696 1.000 33.96732  ? 343 ASP A CB  1 
ATOM   2942 C CG  . ASP A 1 343 ? -26.81959 25.70381 -30.67395 1.000 43.12448  ? 343 ASP A CG  1 
ATOM   2943 O OD1 . ASP A 1 343 ? -27.35348 26.10852 -31.72781 1.000 45.32560  ? 343 ASP A OD1 1 
ATOM   2944 O OD2 . ASP A 1 343 ? -27.28615 24.75582 -30.00215 1.000 48.15968  ? 343 ASP A OD2 1 
ATOM   2945 N N   . GLU A 1 344 ? -22.69424 27.64776 -30.16764 1.000 31.71808  ? 344 GLU A N   1 
ATOM   2946 C CA  . GLU A 1 344 ? -21.70105 28.46655 -29.48479 1.000 29.80975  ? 344 GLU A CA  1 
ATOM   2947 C C   . GLU A 1 344 ? -21.09987 29.51567 -30.41362 1.000 33.10529  ? 344 GLU A C   1 
ATOM   2948 O O   . GLU A 1 344 ? -20.72042 30.59915 -29.94683 1.000 31.64522  ? 344 GLU A O   1 
ATOM   2949 C CB  . GLU A 1 344 ? -20.58966 27.59003 -28.88362 1.000 30.87382  ? 344 GLU A CB  1 
ATOM   2950 C CG  . GLU A 1 344 ? -21.03242 26.69904 -27.72936 1.000 30.10270  ? 344 GLU A CG  1 
ATOM   2951 C CD  . GLU A 1 344 ? -21.19033 27.43708 -26.41895 1.000 32.36645  ? 344 GLU A CD  1 
ATOM   2952 O OE1 . GLU A 1 344 ? -20.63900 28.55154 -26.28123 1.000 34.11565  ? 344 GLU A OE1 1 
ATOM   2953 O OE2 . GLU A 1 344 ? -21.88053 26.89461 -25.51887 1.000 35.66661  ? 344 GLU A OE2 1 
ATOM   2954 N N   . VAL A 1 345 ? -20.98358 29.22233 -31.71354 1.000 31.83035  ? 345 VAL A N   1 
ATOM   2955 C CA  . VAL A 1 345 ? -20.53426 30.25303 -32.65505 1.000 33.42175  ? 345 VAL A CA  1 
ATOM   2956 C C   . VAL A 1 345 ? -21.52236 31.40454 -32.69308 1.000 32.68819  ? 345 VAL A C   1 
ATOM   2957 O O   . VAL A 1 345 ? -21.14257 32.58137 -32.61104 1.000 33.14433  ? 345 VAL A O   1 
ATOM   2958 C CB  . VAL A 1 345 ? -20.32766 29.66967 -34.06597 1.000 32.83438  ? 345 VAL A CB  1 
ATOM   2959 C CG1 . VAL A 1 345 ? -19.98456 30.79695 -35.08147 1.000 30.98185  ? 345 VAL A CG1 1 
ATOM   2960 C CG2 . VAL A 1 345 ? -19.23940 28.59207 -34.04900 1.000 33.18212  ? 345 VAL A CG2 1 
ATOM   2961 N N   . ILE A 1 346 ? -22.80422 31.08880 -32.87467 1.000 32.26679  ? 346 ILE A N   1 
ATOM   2962 C CA  . ILE A 1 346 ? -23.75283 32.15680 -33.11341 1.000 35.77873  ? 346 ILE A CA  1 
ATOM   2963 C C   . ILE A 1 346 ? -24.06879 32.94635 -31.84376 1.000 36.89708  ? 346 ILE A C   1 
ATOM   2964 O O   . ILE A 1 346 ? -24.46873 34.11385 -31.94011 1.000 41.37292  ? 346 ILE A O   1 
ATOM   2965 C CB  . ILE A 1 346 ? -25.01413 31.58543 -33.79346 1.000 46.07113  ? 346 ILE A CB  1 
ATOM   2966 C CG1 . ILE A 1 346 ? -25.72265 30.57928 -32.89521 1.000 56.66980  ? 346 ILE A CG1 1 
ATOM   2967 C CG2 . ILE A 1 346 ? -24.66790 30.93488 -35.14474 1.000 45.23677  ? 346 ILE A CG2 1 
ATOM   2968 C CD1 . ILE A 1 346 ? -27.06131 30.11454 -33.46735 1.000 63.86643  ? 346 ILE A CD1 1 
ATOM   2969 N N   . SER A 1 347 ? -23.86556 32.37399 -30.65598 1.000 32.71597  ? 347 SER A N   1 
ATOM   2970 C CA  . SER A 1 347 ? -24.10361 33.10963 -29.41731 1.000 35.08304  ? 347 SER A CA  1 
ATOM   2971 C C   . SER A 1 347 ? -22.90047 33.94071 -28.95532 1.000 36.23464  ? 347 SER A C   1 
ATOM   2972 O O   . SER A 1 347 ? -23.01394 34.66166 -27.95954 1.000 36.47214  ? 347 SER A O   1 
ATOM   2973 C CB  . SER A 1 347 ? -24.52102 32.14135 -28.30072 1.000 37.05513  ? 347 SER A CB  1 
ATOM   2974 O OG  . SER A 1 347 ? -23.41342 31.35407 -27.88541 1.000 38.41232  ? 347 SER A OG  1 
ATOM   2975 N N   . PHE A 1 348 ? -21.76318 33.87722 -29.64846 1.000 35.18307  ? 348 PHE A N   1 
ATOM   2976 C CA  . PHE A 1 348 ? -20.56341 34.59054 -29.20392 1.000 30.02066  ? 348 PHE A CA  1 
ATOM   2977 C C   . PHE A 1 348 ? -20.78832 36.09793 -29.16153 1.000 34.76405  ? 348 PHE A C   1 
ATOM   2978 O O   . PHE A 1 348 ? -21.32693 36.68615 -30.10188 1.000 35.40689  ? 348 PHE A O   1 
ATOM   2979 C CB  . PHE A 1 348 ? -19.38683 34.29985 -30.13052 1.000 29.26574  ? 348 PHE A CB  1 
ATOM   2980 C CG  . PHE A 1 348 ? -18.16618 35.10165 -29.81099 1.000 29.92595  ? 348 PHE A CG  1 
ATOM   2981 C CD1 . PHE A 1 348 ? -17.34366 34.74394 -28.74361 1.000 32.32342  ? 348 PHE A CD1 1 
ATOM   2982 C CD2 . PHE A 1 348 ? -17.83075 36.22204 -30.56290 1.000 35.25298  ? 348 PHE A CD2 1 
ATOM   2983 C CE1 . PHE A 1 348 ? -16.20623 35.48197 -28.44807 1.000 33.75723  ? 348 PHE A CE1 1 
ATOM   2984 C CE2 . PHE A 1 348 ? -16.68445 36.96896 -30.27232 1.000 32.86635  ? 348 PHE A CE2 1 
ATOM   2985 C CZ  . PHE A 1 348 ? -15.87824 36.60270 -29.21097 1.000 33.71353  ? 348 PHE A CZ  1 
ATOM   2986 N N   . VAL A 1 349 ? -20.32246 36.72230 -28.08196 1.000 34.59712  ? 349 VAL A N   1 
ATOM   2987 C CA  . VAL A 1 349 ? -20.36038 38.16946 -27.89633 1.000 34.32058  ? 349 VAL A CA  1 
ATOM   2988 C C   . VAL A 1 349 ? -18.93427 38.67661 -27.75054 1.000 34.72431  ? 349 VAL A C   1 
ATOM   2989 O O   . VAL A 1 349 ? -18.19853 38.18805 -26.88978 1.000 36.57647  ? 349 VAL A O   1 
ATOM   2990 C CB  . VAL A 1 349 ? -21.19284 38.58896 -26.67260 1.000 40.97195  ? 349 VAL A CB  1 
ATOM   2991 C CG1 . VAL A 1 349 ? -21.40398 40.07668 -26.68204 1.000 44.08685  ? 349 VAL A CG1 1 
ATOM   2992 C CG2 . VAL A 1 349 ? -22.53380 37.90564 -26.71963 1.000 43.82493  ? 349 VAL A CG2 1 
ATOM   2993 N N   . PRO A 1 350 ? -18.52100 39.66180 -28.54667 1.000 39.51204  ? 350 PRO A N   1 
ATOM   2994 C CA  . PRO A 1 350 ? -17.12361 40.08267 -28.53247 1.000 41.94477  ? 350 PRO A CA  1 
ATOM   2995 C C   . PRO A 1 350 ? -16.76694 40.72741 -27.19945 1.000 42.12117  ? 350 PRO A C   1 
ATOM   2996 O O   . PRO A 1 350 ? -17.63684 41.28997 -26.52011 1.000 43.93665  ? 350 PRO A O   1 
ATOM   2997 C CB  . PRO A 1 350 ? -17.05239 41.11310 -29.67261 1.000 46.19290  ? 350 PRO A CB  1 
ATOM   2998 C CG  . PRO A 1 350 ? -18.25179 40.84518 -30.50888 1.000 46.95375  ? 350 PRO A CG  1 
ATOM   2999 C CD  . PRO A 1 350 ? -19.30650 40.36706 -29.57010 1.000 43.65036  ? 350 PRO A CD  1 
ATOM   3000 N N   . PRO A 1 351 ? -15.50080 40.68644 -26.81076 1.000 43.11101  ? 351 PRO A N   1 
ATOM   3001 C CA  . PRO A 1 351 ? -15.07779 41.42000 -25.62663 1.000 49.29463  ? 351 PRO A CA  1 
ATOM   3002 C C   . PRO A 1 351 ? -15.14962 42.91331 -25.87695 1.000 57.37510  ? 351 PRO A C   1 
ATOM   3003 O O   . PRO A 1 351 ? -15.16859 43.35982 -27.03523 1.000 55.00830  ? 351 PRO A O   1 
ATOM   3004 C CB  . PRO A 1 351 ? -13.62411 40.96379 -25.43706 1.000 49.28611  ? 351 PRO A CB  1 
ATOM   3005 C CG  . PRO A 1 351 ? -13.17244 40.64672 -26.84513 1.000 45.95396  ? 351 PRO A CG  1 
ATOM   3006 C CD  . PRO A 1 351 ? -14.38011 39.98455 -27.45882 1.000 41.76386  ? 351 PRO A CD  1 
ATOM   3007 N N   . PRO A 1 352 ? -15.18403 43.71783 -24.82050 1.000 64.19440  ? 352 PRO A N   1 
ATOM   3008 C CA  . PRO A 1 352 ? -14.95000 45.15606 -24.99078 1.000 69.67292  ? 352 PRO A CA  1 
ATOM   3009 C C   . PRO A 1 352 ? -13.48339 45.42983 -25.29007 1.000 75.05046  ? 352 PRO A C   1 
ATOM   3010 O O   . PRO A 1 352 ? -12.59425 44.65619 -24.92516 1.000 73.72399  ? 352 PRO A O   1 
ATOM   3011 C CB  . PRO A 1 352 ? -15.36789 45.75631 -23.64314 1.000 70.34495  ? 352 PRO A CB  1 
ATOM   3012 C CG  . PRO A 1 352 ? -15.43615 44.60227 -22.67133 1.000 70.18140  ? 352 PRO A CG  1 
ATOM   3013 C CD  . PRO A 1 352 ? -15.29505 43.30908 -23.40962 1.000 65.79618  ? 352 PRO A CD  1 
ATOM   3014 N N   . LEU A 1 353 ? -13.23321 46.53987 -25.97612 1.000 79.78464  ? 353 LEU A N   1 
ATOM   3015 C CA  . LEU A 1 353 ? -11.85831 46.94119 -26.25973 1.000 79.98416  ? 353 LEU A CA  1 
ATOM   3016 C C   . LEU A 1 353 ? -11.23820 47.62039 -25.04127 1.000 80.53350  ? 353 LEU A C   1 
ATOM   3017 O O   . LEU A 1 353 ? -10.08752 47.35322 -24.68648 1.000 80.32977  ? 353 LEU A O   1 
ATOM   3018 C CB  . LEU A 1 353 ? -11.79442 47.87372 -27.47094 1.000 79.17853  ? 353 LEU A CB  1 
ATOM   3019 C CG  . LEU A 1 353 ? -11.40624 47.21317 -28.79743 1.000 75.67295  ? 353 LEU A CG  1 
ATOM   3020 C CD1 . LEU A 1 353 ? -11.91718 48.02058 -29.98440 1.000 75.08397  ? 353 LEU A CD1 1 
ATOM   3021 C CD2 . LEU A 1 353 ? -9.90002  47.00047 -28.87663 1.000 72.94624  ? 353 LEU A CD2 1 
HETATM 3022 C C01 . 6GI B 2 .   ? -0.24449  6.12956  -22.30584 1.000 111.83197 ? 401 6GI A C01 1 
HETATM 3023 C C02 . 6GI B 2 .   ? 0.76405   5.18619  -22.25244 1.000 107.34079 ? 401 6GI A C02 1 
HETATM 3024 C C03 . 6GI B 2 .   ? 2.13219   5.54851  -22.31130 1.000 104.54858 ? 401 6GI A C03 1 
HETATM 3025 C C04 . 6GI B 2 .   ? 2.48062   6.88586  -22.42600 1.000 104.42254 ? 401 6GI A C04 1 
HETATM 3026 C C05 . 6GI B 2 .   ? 1.43748   7.90769  -22.48602 1.000 108.96852 ? 401 6GI A C05 1 
HETATM 3027 C C08 . 6GI B 2 .   ? 0.23521   9.82479  -22.61030 1.000 110.46392 ? 401 6GI A C08 1 
HETATM 3028 C C09 . 6GI B 2 .   ? -0.67874  8.71491  -22.50239 1.000 112.22823 ? 401 6GI A C09 1 
HETATM 3029 C C10 . 6GI B 2 .   ? -0.22232  11.40909 -22.73438 1.000 109.79990 ? 401 6GI A C10 1 
HETATM 3030 C C12 . 6GI B 2 .   ? -2.17382  11.53701 -24.40469 1.000 112.35340 ? 401 6GI A C12 1 
HETATM 3031 C C13 . 6GI B 2 .   ? -2.55235  10.24602 -24.82310 1.000 111.59811 ? 401 6GI A C13 1 
HETATM 3032 C C14 . 6GI B 2 .   ? -3.87463  9.92266  -25.24440 1.000 112.13996 ? 401 6GI A C14 1 
HETATM 3033 C C15 . 6GI B 2 .   ? -4.95819  10.86015 -25.28444 1.000 114.62399 ? 401 6GI A C15 1 
HETATM 3034 C C16 . 6GI B 2 .   ? -4.55436  12.13063 -24.86663 1.000 113.73591 ? 401 6GI A C16 1 
HETATM 3035 C C17 . 6GI B 2 .   ? -3.23966  12.46867 -24.44248 1.000 113.33212 ? 401 6GI A C17 1 
HETATM 3036 C C18 . 6GI B 2 .   ? -6.48185  10.49293 -25.76899 1.000 118.18307 ? 401 6GI A C18 1 
HETATM 3037 C C20 . 6GI B 2 .   ? -8.34516  11.70505 -26.96228 1.000 119.41043 ? 401 6GI A C20 1 
HETATM 3038 C C22 . 6GI B 2 .   ? -7.16402  9.79863  -28.12278 1.000 120.84876 ? 401 6GI A C22 1 
HETATM 3039 C C25 . 6GI B 2 .   ? -8.00039  12.59905 -24.85031 1.000 120.15703 ? 401 6GI A C25 1 
HETATM 3040 C C26 . 6GI B 2 .   ? -9.04012  13.31555 -25.43902 1.000 122.12518 ? 401 6GI A C26 1 
HETATM 3041 C C28 . 6GI B 2 .   ? -7.58129  12.96551 -23.51093 1.000 118.40471 ? 401 6GI A C28 1 
HETATM 3042 C C29 . 6GI B 2 .   ? -8.21639  14.02160 -22.79841 1.000 116.06660 ? 401 6GI A C29 1 
HETATM 3043 C C30 . 6GI B 2 .   ? -9.27980  14.75596 -23.33866 1.000 116.22268 ? 401 6GI A C30 1 
HETATM 3044 C C31 . 6GI B 2 .   ? -9.69144  14.42878 -24.69278 1.000 120.32269 ? 401 6GI A C31 1 
HETATM 3045 C C33 . 6GI B 2 .   ? -8.03604  15.74303 -21.19285 1.000 110.49101 ? 401 6GI A C33 1 
HETATM 3046 C C34 . 6GI B 2 .   ? -7.70188  16.72501 -22.37603 1.000 108.29291 ? 401 6GI A C34 1 
HETATM 3047 C C35 . 6GI B 2 .   ? -9.04246  17.06534 -22.96157 1.000 108.99171 ? 401 6GI A C35 1 
HETATM 3048 N N06 . 6GI B 2 .   ? 0.10754   7.52171  -22.42579 1.000 112.73481 ? 401 6GI A N06 1 
HETATM 3049 N N07 . 6GI B 2 .   ? 1.54672   9.28641  -22.59562 1.000 109.60042 ? 401 6GI A N07 1 
HETATM 3050 N N19 . 6GI B 2 .   ? -7.51360  11.58234 -25.78881 1.000 118.93146 ? 401 6GI A N19 1 
HETATM 3051 N N21 . 6GI B 2 .   ? -8.16364  10.82545 -28.12624 1.000 118.29710 ? 401 6GI A N21 1 
HETATM 3052 N N23 . 6GI B 2 .   ? -6.41029  9.64389  -27.03945 1.000 120.43874 ? 401 6GI A N23 1 
HETATM 3053 N N24 . 6GI B 2 .   ? -7.00386  8.93942  -29.29365 1.000 123.34457 ? 401 6GI A N24 1 
HETATM 3054 N N27 . 6GI B 2 .   ? -9.26141  12.75068 -26.79225 1.000 122.47250 ? 401 6GI A N27 1 
HETATM 3055 O O11 . 6GI B 2 .   ? -0.87399  11.93368 -23.95598 1.000 111.30693 ? 401 6GI A O11 1 
HETATM 3056 O O32 . 6GI B 2 .   ? -7.76007  14.36222 -21.49528 1.000 113.75073 ? 401 6GI A O32 1 
HETATM 3057 O O36 . 6GI B 2 .   ? -9.87685  15.88161 -22.71063 1.000 112.20604 ? 401 6GI A O36 1 
HETATM 3058 H H1  . 6GI B 2 .   ? -1.27753  5.82517  -22.25823 1.000 134.20980 ? 401 6GI A H1  1 
HETATM 3059 H H2  . 6GI B 2 .   ? 0.52404   4.10428  -22.16070 1.000 128.82039 ? 401 6GI A H2  1 
HETATM 3060 H H3  . 6GI B 2 .   ? 2.90079   4.76433  -22.26525 1.000 125.46973 ? 401 6GI A H3  1 
HETATM 3061 H H4  . 6GI B 2 .   ? 3.52335   7.13539  -22.46803 1.000 125.31849 ? 401 6GI A H4  1 
HETATM 3062 H H5  . 6GI B 2 .   ? -1.74743  8.72717  -22.47954 1.000 134.68532 ? 401 6GI A H5  1 
HETATM 3063 H H6  . 6GI B 2 .   ? -0.90320  11.62079 -21.88891 1.000 131.77131 ? 401 6GI A H6  1 
HETATM 3064 H H7  . 6GI B 2 .   ? 0.67930   12.02529 -22.55942 1.000 131.77131 ? 401 6GI A H7  1 
HETATM 3065 H H8  . 6GI B 2 .   ? -1.78436  9.45710  -24.82111 1.000 133.92917 ? 401 6GI A H8  1 
HETATM 3066 H H9  . 6GI B 2 .   ? -4.04812  8.88420  -25.55249 1.000 134.57938 ? 401 6GI A H9  1 
HETATM 3067 H H10 . 6GI B 2 .   ? -5.32301  12.91749 -24.87197 1.000 136.49453 ? 401 6GI A H10 1 
HETATM 3068 H H11 . 6GI B 2 .   ? -3.05580  13.49877 -24.13367 1.000 136.00998 ? 401 6GI A H11 1 
HETATM 3069 H H12 . 6GI B 2 .   ? -6.99716  9.84955  -24.98732 1.000 141.83112 ? 401 6GI A H12 1 
HETATM 3070 H H14 . 6GI B 2 .   ? -6.77765  12.41979 -23.06709 1.000 142.09709 ? 401 6GI A H14 1 
HETATM 3071 H H15 . 6GI B 2 .   ? -10.48329 15.03208 -25.11417 1.000 144.39866 ? 401 6GI A H15 1 
HETATM 3072 H H16 . 6GI B 2 .   ? -9.08802  15.86723 -20.89632 1.000 132.60065 ? 401 6GI A H16 1 
HETATM 3073 H H17 . 6GI B 2 .   ? -7.48984  16.05386 -20.29005 1.000 132.60065 ? 401 6GI A H17 1 
HETATM 3074 H H18 . 6GI B 2 .   ? -7.13634  17.62671 -22.06107 1.000 129.96293 ? 401 6GI A H18 1 
HETATM 3075 H H19 . 6GI B 2 .   ? -7.00770  16.29650 -23.12875 1.000 129.96293 ? 401 6GI A H19 1 
HETATM 3076 H H20 . 6GI B 2 .   ? -8.95654  17.36758 -24.03138 1.000 130.80149 ? 401 6GI A H20 1 
HETATM 3077 H H21 . 6GI B 2 .   ? -9.43852  18.02188 -22.54756 1.000 130.80149 ? 401 6GI A H21 1 
HETATM 3078 H H24 . 6GI B 2 .   ? -6.33262  8.19251  -29.38917 1.000 148.02492 ? 401 6GI A H24 1 
HETATM 3079 H H25 . 6GI B 2 .   ? -7.54873  8.98421  -30.16417 1.000 148.02492 ? 401 6GI A H25 1 
HETATM 3080 C C1  . GOL C 3 .   ? 20.28321  23.09325 -21.88027 1.000 44.59056  ? 402 GOL A C1  1 
HETATM 3081 O O1  . GOL C 3 .   ? 20.47674  23.94971 -23.04424 1.000 47.98652  ? 402 GOL A O1  1 
HETATM 3082 C C2  . GOL C 3 .   ? 21.59064  22.20194 -21.79053 1.000 51.79649  ? 402 GOL A C2  1 
HETATM 3083 O O2  . GOL C 3 .   ? 21.63108  21.26009 -20.74622 1.000 49.84011  ? 402 GOL A O2  1 
HETATM 3084 C C3  . GOL C 3 .   ? 21.61407  21.50143 -23.17767 1.000 48.09922  ? 402 GOL A C3  1 
HETATM 3085 O O3  . GOL C 3 .   ? 22.92101  21.04602 -23.45838 1.000 44.79022  ? 402 GOL A O3  1 
HETATM 3086 H H11 . GOL C 3 .   ? 20.16953  23.59328 -21.05690 1.000 53.52011  ? 402 GOL A H11 1 
HETATM 3087 H H12 . GOL C 3 .   ? 19.50182  22.52340 -21.95515 1.000 53.52011  ? 402 GOL A H12 1 
HETATM 3088 H HO1 . GOL C 3 .   ? 21.34576  24.00269 -23.17661 1.000 57.59526  ? 402 GOL A HO1 1 
HETATM 3089 H H2  . GOL C 3 .   ? 22.35259  22.77287 -21.60517 1.000 62.16722  ? 402 GOL A H2  1 
HETATM 3090 H HO2 . GOL C 3 .   ? 20.87049  20.91627 -20.66946 1.000 59.81957  ? 402 GOL A HO2 1 
HETATM 3091 H H31 . GOL C 3 .   ? 20.96141  20.78401 -23.16231 1.000 57.73050  ? 402 GOL A H31 1 
HETATM 3092 H H32 . GOL C 3 .   ? 21.28613  22.13215 -23.83763 1.000 57.73050  ? 402 GOL A H32 1 
HETATM 3093 H HO3 . GOL C 3 .   ? 23.31394  21.67651 -23.85980 1.000 53.75970  ? 402 GOL A HO3 1 
HETATM 3094 C C1  . GOL D 3 .   ? 17.24723  3.26513  -21.56217 1.000 67.00668  ? 403 GOL A C1  1 
HETATM 3095 O O1  . GOL D 3 .   ? 15.84002  3.35843  -21.56712 1.000 61.83688  ? 403 GOL A O1  1 
HETATM 3096 C C2  . GOL D 3 .   ? 17.88439  4.56997  -20.99810 1.000 62.82322  ? 403 GOL A C2  1 
HETATM 3097 O O2  . GOL D 3 .   ? 17.41327  5.70021  -21.60695 1.000 58.09755  ? 403 GOL A O2  1 
HETATM 3098 C C3  . GOL D 3 .   ? 17.56760  4.55113  -19.48913 1.000 58.79657  ? 403 GOL A C3  1 
HETATM 3099 O O3  . GOL D 3 .   ? 18.41638  5.47435  -18.84336 1.000 48.60310  ? 403 GOL A O3  1 
HETATM 3100 H H11 . GOL D 3 .   ? 17.55694  2.51973  -21.02426 1.000 80.41946  ? 403 GOL A H11 1 
HETATM 3101 H H12 . GOL D 3 .   ? 17.60147  3.11549  -22.45269 1.000 80.41946  ? 403 GOL A H12 1 
HETATM 3102 H HO1 . GOL D 3 .   ? 15.63978  4.17420  -21.41096 1.000 74.21570  ? 403 GOL A HO1 1 
HETATM 3103 H H2  . GOL D 3 .   ? 18.84072  4.56556  -21.16032 1.000 75.39930  ? 403 GOL A H2  1 
HETATM 3104 H HO2 . GOL D 3 .   ? 17.02942  6.16236  -21.01005 1.000 69.72850  ? 403 GOL A HO2 1 
HETATM 3105 H H31 . GOL D 3 .   ? 16.62635  4.75385  -19.37137 1.000 70.56732  ? 403 GOL A H31 1 
HETATM 3106 H H32 . GOL D 3 .   ? 17.67682  3.64354  -19.16470 1.000 70.56732  ? 403 GOL A H32 1 
HETATM 3107 H HO3 . GOL D 3 .   ? 18.80849  5.92395  -19.45729 1.000 58.33516  ? 403 GOL A HO3 1 
HETATM 3108 C C1  . GOL E 3 .   ? -27.45876 10.08673 -30.05093 1.000 84.62285  ? 404 GOL A C1  1 
HETATM 3109 O O1  . GOL E 3 .   ? -26.36515 10.15973 -29.19824 1.000 79.93788  ? 404 GOL A O1  1 
HETATM 3110 C C2  . GOL E 3 .   ? -28.71552 9.82826  -29.17141 1.000 89.51070  ? 404 GOL A C2  1 
HETATM 3111 O O2  . GOL E 3 .   ? -28.46262 9.94596  -27.83380 1.000 91.48321  ? 404 GOL A O2  1 
HETATM 3112 C C3  . GOL E 3 .   ? -29.68471 10.88565 -29.72034 1.000 88.67261  ? 404 GOL A C3  1 
HETATM 3113 O O3  . GOL E 3 .   ? -29.54849 11.99688 -28.90320 1.000 88.94149  ? 404 GOL A O3  1 
HETATM 3114 H H11 . GOL E 3 .   ? -27.58797 10.90162 -30.56099 1.000 101.55885 ? 404 GOL A H11 1 
HETATM 3115 H H12 . GOL E 3 .   ? -27.37429 9.37482  -30.70434 1.000 101.55885 ? 404 GOL A H12 1 
HETATM 3116 H HO1 . GOL E 3 .   ? -25.82268 10.72869 -29.53375 1.000 95.93690  ? 404 GOL A HO1 1 
HETATM 3117 H H2  . GOL E 3 .   ? -29.06021 8.92527  -29.25318 1.000 107.42427 ? 404 GOL A H2  1 
HETATM 3118 H HO2 . GOL E 3 .   ? -27.75843 10.37297 -27.75220 1.000 109.79129 ? 404 GOL A HO2 1 
HETATM 3119 H H31 . GOL E 3 .   ? -29.47048 11.06030 -30.65012 1.000 106.41857 ? 404 GOL A H31 1 
HETATM 3120 H H32 . GOL E 3 .   ? -30.58276 10.51912 -29.72874 1.000 106.41857 ? 404 GOL A H32 1 
HETATM 3121 H HO3 . GOL E 3 .   ? -28.72602 12.25556 -28.92952 1.000 106.74123 ? 404 GOL A HO3 1 
HETATM 3122 C C1  . GOL F 3 .   ? -5.55131  30.05055 -31.16540 1.000 92.17060  ? 405 GOL A C1  1 
HETATM 3123 O O1  . GOL F 3 .   ? -6.76462  29.50733 -31.56720 1.000 89.94682  ? 405 GOL A O1  1 
HETATM 3124 C C2  . GOL F 3 .   ? -5.12183  29.32179 -29.89086 1.000 94.73252  ? 405 GOL A C2  1 
HETATM 3125 O O2  . GOL F 3 .   ? -4.20694  28.33573 -30.14761 1.000 95.08966  ? 405 GOL A O2  1 
HETATM 3126 C C3  . GOL F 3 .   ? -4.52011  30.43563 -29.03274 1.000 95.05840  ? 405 GOL A C3  1 
HETATM 3127 O O3  . GOL F 3 .   ? -4.03757  29.83691 -27.86622 1.000 91.37144  ? 405 GOL A O3  1 
HETATM 3128 H H11 . GOL F 3 .   ? -4.85907  29.95183 -31.83768 1.000 110.61616 ? 405 GOL A H11 1 
HETATM 3129 H H12 . GOL F 3 .   ? -5.61177  31.00149 -30.98387 1.000 110.61616 ? 405 GOL A H12 1 
HETATM 3130 H HO1 . GOL F 3 .   ? -6.70224  28.66562 -31.44902 1.000 107.94762 ? 405 GOL A HO1 1 
HETATM 3131 H H2  . GOL F 3 .   ? -5.87447  28.88638 -29.46091 1.000 113.69046 ? 405 GOL A H2  1 
HETATM 3132 H HO2 . GOL F 3 .   ? -3.47106  28.71850 -30.31376 1.000 114.11903 ? 405 GOL A HO2 1 
HETATM 3133 H H31 . GOL F 3 .   ? -3.83249  30.88920 -29.54495 1.000 114.08151 ? 405 GOL A H31 1 
HETATM 3134 H H32 . GOL F 3 .   ? -5.20094  31.10646 -28.86737 1.000 114.08151 ? 405 GOL A H32 1 
HETATM 3135 H HO3 . GOL F 3 .   ? -3.89402  29.01633 -28.05281 1.000 109.65717 ? 405 GOL A HO3 1 
HETATM 3136 C C1  . GOL G 3 .   ? -19.36750 30.17927 -23.22676 1.000 67.38016  ? 406 GOL A C1  1 
HETATM 3137 O O1  . GOL G 3 .   ? -20.28494 29.54043 -24.01784 1.000 62.66669  ? 406 GOL A O1  1 
HETATM 3138 C C2  . GOL G 3 .   ? -19.70393 31.69648 -23.16158 1.000 70.85487  ? 406 GOL A C2  1 
HETATM 3139 O O2  . GOL G 3 .   ? -21.03023 31.97525 -23.29454 1.000 70.55696  ? 406 GOL A O2  1 
HETATM 3140 C C3  . GOL G 3 .   ? -19.17100 32.04754 -21.75259 1.000 76.27354  ? 406 GOL A C3  1 
HETATM 3141 O O3  . GOL G 3 .   ? -19.05894 33.42120 -21.67063 1.000 80.47099  ? 406 GOL A O3  1 
HETATM 3142 H H11 . GOL G 3 .   ? -19.35671 29.82631 -22.32332 1.000 80.86763  ? 406 GOL A H11 1 
HETATM 3143 H H12 . GOL G 3 .   ? -18.46318 30.07767 -23.56258 1.000 80.86763  ? 406 GOL A H12 1 
HETATM 3144 H HO1 . GOL G 3 .   ? -20.95701 30.07221 -24.08415 1.000 75.21146  ? 406 GOL A HO1 1 
HETATM 3145 H H2  . GOL G 3 .   ? -19.29139 32.19457 -23.88450 1.000 85.03728  ? 406 GOL A H2  1 
HETATM 3146 H HO2 . GOL G 3 .   ? -21.36664 31.92672 -22.53781 1.000 84.67979  ? 406 GOL A HO2 1 
HETATM 3147 H H31 . GOL G 3 .   ? -19.77522 31.67402 -21.09205 1.000 91.53968  ? 406 GOL A H31 1 
HETATM 3148 H H32 . GOL G 3 .   ? -18.32782 31.58732 -21.61790 1.000 91.53968  ? 406 GOL A H32 1 
HETATM 3149 H HO3 . GOL G 3 .   ? -19.73303 33.73138 -22.08211 1.000 96.57662  ? 406 GOL A HO3 1 
HETATM 3150 O O   . HOH H 4 .   ? -2.73434  15.05167 -5.67116  1.000 62.76726  ? 501 HOH A O   1 
HETATM 3151 O O   . HOH H 4 .   ? -5.01123  23.43210 -7.36807  1.000 49.49403  ? 502 HOH A O   1 
HETATM 3152 O O   . HOH H 4 .   ? -15.81835 29.47564 -47.57009 1.000 50.62426  ? 503 HOH A O   1 
HETATM 3153 O O   . HOH H 4 .   ? 22.83276  15.42684 -15.30932 1.000 45.16289  ? 504 HOH A O   1 
HETATM 3154 O O   . HOH H 4 .   ? 6.63696   7.16331  2.34972   1.000 82.42049  ? 505 HOH A O   1 
HETATM 3155 O O   . HOH H 4 .   ? -10.97028 20.58035 -34.11778 1.000 67.64552  ? 506 HOH A O   1 
HETATM 3156 O O   . HOH H 4 .   ? 4.22541   19.46635 -22.14546 1.000 54.10830  ? 507 HOH A O   1 
HETATM 3157 O O   . HOH H 4 .   ? 4.34922   21.47530 -29.03096 1.000 75.74888  ? 508 HOH A O   1 
HETATM 3158 O O   . HOH H 4 .   ? -16.48929 39.43087 -22.90092 1.000 67.03883  ? 509 HOH A O   1 
HETATM 3159 O O   . HOH H 4 .   ? 7.44244   4.65223  -13.07581 1.000 49.44621  ? 510 HOH A O   1 
HETATM 3160 O O   . HOH H 4 .   ? 9.93213   28.46629 -29.10539 1.000 62.31230  ? 511 HOH A O   1 
HETATM 3161 O O   . HOH H 4 .   ? 5.79718   8.69310  -26.28076 1.000 54.05829  ? 512 HOH A O   1 
HETATM 3162 O O   . HOH H 4 .   ? 8.76099   40.22311 -5.51382  1.000 61.19070  ? 513 HOH A O   1 
HETATM 3163 O O   . HOH H 4 .   ? -3.38836  42.29802 -30.57348 1.000 48.73322  ? 514 HOH A O   1 
HETATM 3164 O O   . HOH H 4 .   ? 18.31707  22.71016 -0.45732  1.000 38.46773  ? 515 HOH A O   1 
HETATM 3165 O O   . HOH H 4 .   ? 20.22488  7.46803  -19.34102 1.000 47.81605  ? 516 HOH A O   1 
HETATM 3166 O O   . HOH H 4 .   ? 4.16188   19.09718 -25.37793 1.000 50.84830  ? 517 HOH A O   1 
HETATM 3167 O O   . HOH H 4 .   ? 4.85893   3.97726  -16.93204 1.000 53.35994  ? 518 HOH A O   1 
HETATM 3168 O O   . HOH H 4 .   ? -6.95448  49.18582 -30.91573 1.000 56.73932  ? 519 HOH A O   1 
HETATM 3169 O O   . HOH H 4 .   ? -22.94887 24.48410 -25.68519 1.000 34.49721  ? 520 HOH A O   1 
HETATM 3170 O O   . HOH H 4 .   ? -3.32059  7.23921  -6.55747  1.000 70.95080  ? 521 HOH A O   1 
HETATM 3171 O O   . HOH H 4 .   ? -6.31304  26.56547 -27.95192 1.000 59.62698  ? 522 HOH A O   1 
HETATM 3172 O O   . HOH H 4 .   ? 15.32889  43.93466 -13.98319 1.000 71.93128  ? 523 HOH A O   1 
HETATM 3173 O O   . HOH H 4 .   ? 4.59499   11.45925 -0.00579  1.000 44.83533  ? 524 HOH A O   1 
HETATM 3174 O O   . HOH H 4 .   ? -18.79380 43.51230 -43.77588 1.000 37.55420  ? 525 HOH A O   1 
HETATM 3175 O O   . HOH H 4 .   ? -11.09363 51.40652 -38.35713 1.000 32.77855  ? 526 HOH A O   1 
HETATM 3176 O O   . HOH H 4 .   ? -14.37877 28.62066 -45.34151 1.000 38.10967  ? 527 HOH A O   1 
HETATM 3177 O O   . HOH H 4 .   ? 18.36501  34.83120 -14.23047 1.000 66.91923  ? 528 HOH A O   1 
HETATM 3178 O O   . HOH H 4 .   ? -3.73211  10.75717 -3.15246  1.000 50.04743  ? 529 HOH A O   1 
HETATM 3179 O O   . HOH H 4 .   ? 11.52069  19.84416 -2.12038  1.000 56.01477  ? 530 HOH A O   1 
HETATM 3180 O O   . HOH H 4 .   ? 5.54805   29.68280 -29.64441 1.000 48.93829  ? 531 HOH A O   1 
HETATM 3181 O O   . HOH H 4 .   ? 11.55930  -3.82610 -8.21376  1.000 51.50066  ? 532 HOH A O   1 
HETATM 3182 O O   . HOH H 4 .   ? 2.61128   18.96237 -18.86318 1.000 43.80449  ? 533 HOH A O   1 
HETATM 3183 O O   . HOH H 4 .   ? 4.17420   12.01608 -9.00860  1.000 49.45851  ? 534 HOH A O   1 
HETATM 3184 O O   . HOH H 4 .   ? -17.71120 39.82890 -50.93396 1.000 49.16086  ? 535 HOH A O   1 
HETATM 3185 O O   . HOH H 4 .   ? -14.99313 22.87304 -14.44581 1.000 37.80011  ? 536 HOH A O   1 
HETATM 3186 O O   . HOH H 4 .   ? 20.69555  21.20441 -18.30117 1.000 35.71993  ? 537 HOH A O   1 
HETATM 3187 O O   . HOH H 4 .   ? -13.51682 24.97638 -46.81626 1.000 64.71199  ? 538 HOH A O   1 
HETATM 3188 O O   . HOH H 4 .   ? -27.92571 22.27341 -30.55963 1.000 45.77156  ? 539 HOH A O   1 
HETATM 3189 O O   . HOH H 4 .   ? 18.68603  17.18256 -14.99065 1.000 38.19403  ? 540 HOH A O   1 
HETATM 3190 O O   . HOH H 4 .   ? -12.91934 24.90705 -40.56281 1.000 41.42151  ? 541 HOH A O   1 
HETATM 3191 O O   . HOH H 4 .   ? 12.94408  42.09591 -21.62666 1.000 78.99599  ? 542 HOH A O   1 
HETATM 3192 O O   . HOH H 4 .   ? -6.35613  39.58219 -47.16529 1.000 56.87886  ? 543 HOH A O   1 
HETATM 3193 O O   . HOH H 4 .   ? -21.59874 33.20242 -25.56226 1.000 40.01764  ? 544 HOH A O   1 
HETATM 3194 O O   . HOH H 4 .   ? 23.21565  29.01150 -3.92819  1.000 47.78129  ? 545 HOH A O   1 
HETATM 3195 O O   . HOH H 4 .   ? -20.47011 30.40997 -15.41587 1.000 40.72247  ? 546 HOH A O   1 
HETATM 3196 O O   . HOH H 4 .   ? 8.20012   16.49231 -30.47103 1.000 62.15524  ? 547 HOH A O   1 
HETATM 3197 O O   . HOH H 4 .   ? -25.45900 8.92511  -26.68930 1.000 61.67739  ? 548 HOH A O   1 
HETATM 3198 O O   . HOH H 4 .   ? -4.53616  35.28475 -4.49072  1.000 39.13357  ? 549 HOH A O   1 
HETATM 3199 O O   . HOH H 4 .   ? -0.14545  10.64241 1.80238   1.000 46.66270  ? 550 HOH A O   1 
HETATM 3200 O O   . HOH H 4 .   ? -14.26129 34.06067 -15.83619 1.000 31.58420  ? 551 HOH A O   1 
HETATM 3201 O O   . HOH H 4 .   ? -13.98690 36.42616 -25.44284 1.000 39.21020  ? 552 HOH A O   1 
HETATM 3202 O O   . HOH H 4 .   ? 16.15639  36.92559 -0.69236  1.000 46.52433  ? 553 HOH A O   1 
HETATM 3203 O O   . HOH H 4 .   ? -12.43644 34.60268 -24.20526 1.000 33.17004  ? 554 HOH A O   1 
HETATM 3204 O O   . HOH H 4 .   ? -11.55317 40.73880 -33.75386 1.000 35.36043  ? 555 HOH A O   1 
HETATM 3205 O O   . HOH H 4 .   ? 11.88553  15.88152 -2.85090  1.000 39.60874  ? 556 HOH A O   1 
HETATM 3206 O O   . HOH H 4 .   ? -17.82357 15.81375 -16.85656 1.000 62.23637  ? 557 HOH A O   1 
HETATM 3207 O O   . HOH H 4 .   ? 14.79616  24.01204 -22.97817 1.000 47.46119  ? 558 HOH A O   1 
HETATM 3208 O O   . HOH H 4 .   ? -12.98958 20.84053 -21.11783 1.000 39.52315  ? 559 HOH A O   1 
HETATM 3209 O O   . HOH H 4 .   ? 15.24524  23.30590 2.30893   1.000 49.63612  ? 560 HOH A O   1 
HETATM 3210 O O   . HOH H 4 .   ? -15.72247 33.45070 -18.04462 1.000 36.63887  ? 561 HOH A O   1 
HETATM 3211 O O   . HOH H 4 .   ? 4.57440   37.94975 -27.90897 1.000 83.30884  ? 562 HOH A O   1 
HETATM 3212 O O   . HOH H 4 .   ? 13.42321  5.98348  -1.82249  1.000 39.93855  ? 563 HOH A O   1 
HETATM 3213 O O   . HOH H 4 .   ? -18.48312 28.67876 -19.86582 1.000 47.21656  ? 564 HOH A O   1 
HETATM 3214 O O   . HOH H 4 .   ? -19.86336 34.80636 -35.59047 1.000 46.38508  ? 565 HOH A O   1 
HETATM 3215 O O   . HOH H 4 .   ? -3.24880  25.40792 -8.36342  1.000 28.89397  ? 566 HOH A O   1 
HETATM 3216 O O   . HOH H 4 .   ? 4.21519   -3.21786 -5.36157  1.000 79.12851  ? 567 HOH A O   1 
HETATM 3217 O O   . HOH H 4 .   ? -25.76755 19.25329 -36.89644 1.000 49.96729  ? 568 HOH A O   1 
HETATM 3218 O O   . HOH H 4 .   ? -30.00592 15.45765 -30.81049 1.000 42.45514  ? 569 HOH A O   1 
HETATM 3219 O O   . HOH H 4 .   ? -16.43271 37.45358 -25.01085 1.000 45.31414  ? 570 HOH A O   1 
HETATM 3220 O O   . HOH H 4 .   ? -18.70210 44.78038 -49.82477 1.000 42.97819  ? 571 HOH A O   1 
HETATM 3221 O O   . HOH H 4 .   ? -5.88170  46.00993 -5.97240  1.000 58.34687  ? 572 HOH A O   1 
HETATM 3222 O O   . HOH H 4 .   ? -20.47575 34.48977 -48.07461 1.000 54.92270  ? 573 HOH A O   1 
HETATM 3223 O O   . HOH H 4 .   ? -0.61535  21.64823 -6.84067  1.000 46.27943  ? 574 HOH A O   1 
HETATM 3224 O O   . HOH H 4 .   ? -6.71267  42.31171 -47.62883 1.000 46.49596  ? 575 HOH A O   1 
HETATM 3225 O O   . HOH H 4 .   ? -28.73574 30.03757 -37.87288 1.000 59.01052  ? 576 HOH A O   1 
HETATM 3226 O O   . HOH H 4 .   ? 13.41717  23.38662 -17.84025 1.000 48.81700  ? 577 HOH A O   1 
HETATM 3227 O O   . HOH H 4 .   ? -18.40375 20.75340 -14.78846 1.000 46.71356  ? 578 HOH A O   1 
HETATM 3228 O O   . HOH H 4 .   ? -1.02763  15.06417 -10.51767 1.000 39.47719  ? 579 HOH A O   1 
HETATM 3229 O O   . HOH H 4 .   ? -26.56754 24.41075 -27.41876 1.000 51.60237  ? 580 HOH A O   1 
HETATM 3230 O O   . HOH H 4 .   ? 10.19804  46.15989 -9.98544  1.000 80.46427  ? 581 HOH A O   1 
HETATM 3231 O O   . HOH H 4 .   ? 4.14089   1.60224  -0.24485  1.000 60.82098  ? 582 HOH A O   1 
HETATM 3232 O O   . HOH H 4 .   ? -7.04329  28.44660 -8.18723  1.000 30.67761  ? 583 HOH A O   1 
HETATM 3233 O O   . HOH H 4 .   ? -17.68253 28.06561 -22.54017 1.000 30.08394  ? 584 HOH A O   1 
HETATM 3234 O O   . HOH H 4 .   ? -0.92756  19.75178 -4.10456  1.000 34.70175  ? 585 HOH A O   1 
HETATM 3235 O O   . HOH H 4 .   ? 4.40526   20.49503 -20.08766 1.000 41.38637  ? 586 HOH A O   1 
HETATM 3236 O O   . HOH H 4 .   ? -6.97022  37.01120 -27.84420 1.000 43.91252  ? 587 HOH A O   1 
HETATM 3237 O O   . HOH H 4 .   ? -8.55260  35.95230 -21.58375 1.000 32.32577  ? 588 HOH A O   1 
HETATM 3238 O O   . HOH H 4 .   ? 3.61574   37.12684 -2.28890  1.000 33.49340  ? 589 HOH A O   1 
HETATM 3239 O O   . HOH H 4 .   ? 5.19747   21.90015 -1.40740  1.000 31.01127  ? 590 HOH A O   1 
HETATM 3240 O O   . HOH H 4 .   ? 21.05538  12.05735 -20.40579 1.000 50.29289  ? 591 HOH A O   1 
HETATM 3241 O O   . HOH H 4 .   ? -9.79511  23.38180 -8.33979  1.000 68.09350  ? 592 HOH A O   1 
HETATM 3242 O O   . HOH H 4 .   ? 17.98928  14.70023 1.32261   1.000 36.30290  ? 593 HOH A O   1 
HETATM 3243 O O   . HOH H 4 .   ? -6.97406  46.36225 -47.88316 1.000 40.51625  ? 594 HOH A O   1 
HETATM 3244 O O   . HOH H 4 .   ? 17.75427  24.58848 -15.07942 1.000 33.26879  ? 595 HOH A O   1 
HETATM 3245 O O   . HOH H 4 .   ? 20.30888  12.44692 -5.26193  1.000 34.07048  ? 596 HOH A O   1 
HETATM 3246 O O   . HOH H 4 .   ? 19.51149  20.28632 -14.33353 1.000 40.18261  ? 597 HOH A O   1 
HETATM 3247 O O   . HOH H 4 .   ? -14.22559 50.53853 -35.60871 1.000 45.13846  ? 598 HOH A O   1 
HETATM 3248 O O   . HOH H 4 .   ? -12.36532 36.94090 -13.21090 1.000 36.14905  ? 599 HOH A O   1 
HETATM 3249 O O   . HOH H 4 .   ? 4.35029   9.33106  -23.19290 1.000 61.44402  ? 600 HOH A O   1 
HETATM 3250 O O   . HOH H 4 .   ? -24.75274 31.36762 -39.41618 1.000 41.81433  ? 601 HOH A O   1 
HETATM 3251 O O   . HOH H 4 .   ? -27.70856 24.42771 -33.89724 1.000 45.37424  ? 602 HOH A O   1 
HETATM 3252 O O   . HOH H 4 .   ? -10.08882 37.66343 -14.82564 1.000 32.58433  ? 603 HOH A O   1 
HETATM 3253 O O   . HOH H 4 .   ? -3.43344  33.63928 -2.71218  1.000 37.50678  ? 604 HOH A O   1 
HETATM 3254 O O   . HOH H 4 .   ? -13.06141 41.37043 -31.40819 1.000 35.22233  ? 605 HOH A O   1 
HETATM 3255 O O   . HOH H 4 .   ? -1.00698  41.41678 -29.77603 1.000 59.98273  ? 606 HOH A O   1 
HETATM 3256 O O   . HOH H 4 .   ? -17.03765 38.71855 -37.53181 1.000 35.13692  ? 607 HOH A O   1 
HETATM 3257 O O   . HOH H 4 .   ? 21.23257  10.31624 -14.19688 1.000 64.07337  ? 608 HOH A O   1 
HETATM 3258 O O   . HOH H 4 .   ? 17.72533  34.50039 -8.37275  1.000 45.46880  ? 609 HOH A O   1 
HETATM 3259 O O   . HOH H 4 .   ? -8.15039  25.60802 -7.75143  1.000 45.48370  ? 610 HOH A O   1 
HETATM 3260 O O   . HOH H 4 .   ? 2.17681   -8.65283 -6.77208  1.000 97.54222  ? 611 HOH A O   1 
HETATM 3261 O O   . HOH H 4 .   ? -25.425   14.387   -20.811   1.000 46.59887  ? 612 HOH A O   1 
HETATM 3262 O O   . HOH H 4 .   ? 9.79666   17.11634 -16.17003 1.000 24.32427  ? 613 HOH A O   1 
HETATM 3263 O O   . HOH H 4 .   ? -21.04546 44.44986 -48.84241 1.000 55.42107  ? 614 HOH A O   1 
HETATM 3264 O O   . HOH H 4 .   ? -5.00406  26.02914 -2.87147  1.000 37.46603  ? 615 HOH A O   1 
HETATM 3265 O O   . HOH H 4 .   ? -10.62465 35.96308 -47.53848 1.000 47.60340  ? 616 HOH A O   1 
HETATM 3266 O O   . HOH H 4 .   ? 2.99250   18.46645 -16.16167 1.000 32.78337  ? 617 HOH A O   1 
HETATM 3267 O O   . HOH H 4 .   ? -5.66560  35.54303 -11.03220 1.000 30.57207  ? 618 HOH A O   1 
HETATM 3268 O O   . HOH H 4 .   ? 12.04762  18.29141 -3.96409  1.000 43.20761  ? 619 HOH A O   1 
HETATM 3269 O O   . HOH H 4 .   ? -0.10191  40.58898 -41.82796 1.000 58.89237  ? 620 HOH A O   1 
HETATM 3270 O O   . HOH H 4 .   ? 18.37580  20.97362 -23.97890 1.000 45.27260  ? 621 HOH A O   1 
HETATM 3271 O O   . HOH H 4 .   ? 9.72566   14.70656 -3.74405  1.000 40.24483  ? 622 HOH A O   1 
HETATM 3272 O O   . HOH H 4 .   ? 13.53242  3.42054  -5.63235  1.000 50.92010  ? 623 HOH A O   1 
HETATM 3273 O O   . HOH H 4 .   ? -23.73812 24.13531 -14.81058 1.000 41.69741  ? 624 HOH A O   1 
HETATM 3274 O O   . HOH H 4 .   ? -2.70289  33.71351 -30.63905 1.000 57.36086  ? 625 HOH A O   1 
HETATM 3275 O O   . HOH H 4 .   ? 18.91237  8.90794  -11.08820 1.000 40.84433  ? 626 HOH A O   1 
HETATM 3276 O O   . HOH H 4 .   ? 1.52846   21.70512 -17.70472 1.000 29.69848  ? 627 HOH A O   1 
HETATM 3277 O O   . HOH H 4 .   ? 8.33883   23.64225 -27.37307 1.000 54.12112  ? 628 HOH A O   1 
HETATM 3278 O O   . HOH H 4 .   ? 2.08861   12.41294 -7.49326  1.000 41.59005  ? 629 HOH A O   1 
HETATM 3279 O O   . HOH H 4 .   ? -22.34449 33.63743 -41.60275 1.000 45.95630  ? 630 HOH A O   1 
HETATM 3280 O O   . HOH H 4 .   ? 16.75104  6.87630  -26.17657 1.000 53.30985  ? 631 HOH A O   1 
HETATM 3281 O O   . HOH H 4 .   ? -6.12332  38.42065 -22.12289 1.000 51.46730  ? 632 HOH A O   1 
HETATM 3282 O O   . HOH H 4 .   ? -17.01321 41.84731 -33.10378 1.000 54.64227  ? 633 HOH A O   1 
HETATM 3283 O O   . HOH H 4 .   ? 11.76105  24.93821 -24.44812 1.000 39.43534  ? 634 HOH A O   1 
HETATM 3284 O O   . HOH H 4 .   ? -7.09984  23.60934 -33.20078 1.000 56.17417  ? 635 HOH A O   1 
HETATM 3285 O O   . HOH H 4 .   ? -3.45881  17.75837 -0.86261  1.000 41.72923  ? 636 HOH A O   1 
HETATM 3286 O O   . HOH H 4 .   ? -10.06286 19.11543 -14.58607 1.000 59.50829  ? 637 HOH A O   1 
HETATM 3287 O O   . HOH H 4 .   ? -1.56106  41.87161 -9.55900  1.000 55.73863  ? 638 HOH A O   1 
HETATM 3288 O O   . HOH H 4 .   ? 22.07440  7.34424  -3.41239  1.000 65.88132  ? 639 HOH A O   1 
HETATM 3289 O O   . HOH H 4 .   ? -18.89946 37.17284 -34.85224 1.000 55.49050  ? 640 HOH A O   1 
HETATM 3290 O O   . HOH H 4 .   ? -21.43408 35.11578 -33.84576 1.000 67.63697  ? 641 HOH A O   1 
HETATM 3291 O O   . HOH H 4 .   ? 27.50145  23.42055 -6.20722  1.000 52.42447  ? 642 HOH A O   1 
HETATM 3292 O O   . HOH H 4 .   ? 15.24249  18.80374 -29.16678 1.000 41.54503  ? 643 HOH A O   1 
HETATM 3293 O O   . HOH H 4 .   ? -17.74792 39.17276 -32.73935 1.000 47.18086  ? 644 HOH A O   1 
HETATM 3294 O O   . HOH H 4 .   ? 11.67725  24.42019 1.00784   1.000 52.79342  ? 645 HOH A O   1 
HETATM 3295 O O   . HOH H 4 .   ? 20.91044  30.28377 -2.72666  1.000 47.67537  ? 646 HOH A O   1 
HETATM 3296 O O   . HOH H 4 .   ? -17.42960 11.08865 -25.73266 1.000 54.23478  ? 647 HOH A O   1 
HETATM 3297 O O   . HOH H 4 .   ? 19.23280  16.00248 -12.36635 1.000 35.26876  ? 648 HOH A O   1 
HETATM 3298 O O   . HOH H 4 .   ? -9.03757  20.35964 -17.61840 1.000 55.84643  ? 649 HOH A O   1 
HETATM 3299 O O   . HOH H 4 .   ? -24.33308 8.18807  -29.50603 1.000 64.34034  ? 650 HOH A O   1 
HETATM 3300 O O   . HOH H 4 .   ? -21.63415 10.30580 -35.61043 1.000 51.66754  ? 651 HOH A O   1 
HETATM 3301 O O   . HOH H 4 .   ? 14.43153  9.70686  -1.25436  1.000 45.95491  ? 652 HOH A O   1 
HETATM 3302 O O   . HOH H 4 .   ? -16.23033 9.02867  -35.64221 1.000 62.37819  ? 653 HOH A O   1 
HETATM 3303 O O   . HOH H 4 .   ? 18.85987  1.47594  -2.67751  1.000 45.09001  ? 654 HOH A O   1 
HETATM 3304 O O   . HOH H 4 .   ? -0.73069  39.95438 -20.33574 1.000 44.47029  ? 655 HOH A O   1 
HETATM 3305 O O   . HOH H 4 .   ? 12.92631  20.51833 -17.69360 1.000 26.33190  ? 656 HOH A O   1 
HETATM 3306 O O   . HOH H 4 .   ? 21.00936  10.34519 -16.91872 1.000 58.83677  ? 657 HOH A O   1 
HETATM 3307 O O   . HOH H 4 .   ? -16.32374 42.18498 -50.33084 1.000 43.62127  ? 658 HOH A O   1 
HETATM 3308 O O   . HOH H 4 .   ? -1.08461  22.24749 -26.36454 1.000 43.23064  ? 659 HOH A O   1 
HETATM 3309 O O   . HOH H 4 .   ? -6.74428  36.55845 -3.02560  1.000 51.61119  ? 660 HOH A O   1 
HETATM 3310 O O   . HOH H 4 .   ? 7.07600   19.23953 -21.88778 1.000 35.81163  ? 661 HOH A O   1 
HETATM 3311 O O   . HOH H 4 .   ? -19.63493 43.29211 -27.01329 1.000 61.20675  ? 662 HOH A O   1 
HETATM 3312 O O   . HOH H 4 .   ? 19.55529  2.40810  -9.81815  1.000 54.32052  ? 663 HOH A O   1 
HETATM 3313 O O   . HOH H 4 .   ? -8.47878  39.08260 -6.36299  1.000 48.09451  ? 664 HOH A O   1 
HETATM 3314 O O   . HOH H 4 .   ? -6.22486  44.30090 -13.08229 1.000 62.04738  ? 665 HOH A O   1 
HETATM 3315 O O   . HOH H 4 .   ? 0.43480   11.42724 -5.37586  1.000 45.59712  ? 666 HOH A O   1 
HETATM 3316 O O   . HOH H 4 .   ? 23.92711  28.05115 -15.90533 1.000 38.01442  ? 667 HOH A O   1 
HETATM 3317 O O   . HOH H 4 .   ? -21.26825 8.45751  -30.16692 1.000 59.04516  ? 668 HOH A O   1 
HETATM 3318 O O   . HOH H 4 .   ? -18.97841 26.48365 -43.29950 1.000 45.90838  ? 669 HOH A O   1 
HETATM 3319 O O   . HOH H 4 .   ? -9.69574  20.52278 -36.24116 1.000 51.52320  ? 670 HOH A O   1 
HETATM 3320 O O   . HOH H 4 .   ? 2.32452   30.36071 0.75835   1.000 55.75614  ? 671 HOH A O   1 
HETATM 3321 O O   . HOH H 4 .   ? 1.65435   24.45603 0.28870   1.000 53.57206  ? 672 HOH A O   1 
HETATM 3322 O O   . HOH H 4 .   ? -5.21011  6.51582  -9.89083  1.000 57.48509  ? 673 HOH A O   1 
HETATM 3323 O O   . HOH H 4 .   ? -29.67140 20.05751 -33.55901 1.000 58.28890  ? 674 HOH A O   1 
HETATM 3324 O O   . HOH H 4 .   ? 19.21950  5.07440  -8.84007  1.000 81.33848  ? 675 HOH A O   1 
HETATM 3325 O O   . HOH H 4 .   ? -6.45206  32.22577 -33.39250 1.000 40.82460  ? 676 HOH A O   1 
HETATM 3326 O O   . HOH H 4 .   ? 22.39673  29.15898 -11.02609 1.000 48.48095  ? 677 HOH A O   1 
HETATM 3327 O O   . HOH H 4 .   ? 12.75482  20.01740 -28.72916 1.000 42.79979  ? 678 HOH A O   1 
HETATM 3328 O O   . HOH H 4 .   ? -20.20501 27.03461 -17.98530 1.000 32.23978  ? 679 HOH A O   1 
HETATM 3329 O O   . HOH H 4 .   ? -14.59027 37.11226 -52.73393 1.000 47.80135  ? 680 HOH A O   1 
HETATM 3330 O O   . HOH H 4 .   ? 23.50804  29.95023 -18.90328 1.000 47.28368  ? 681 HOH A O   1 
HETATM 3331 O O   . HOH H 4 .   ? 7.39030   13.77312 -2.69132  1.000 35.88491  ? 682 HOH A O   1 
HETATM 3332 O O   . HOH H 4 .   ? -16.705   43.022   -41.837   1.000 35.68826  ? 683 HOH A O   1 
HETATM 3333 O O   . HOH H 4 .   ? 17.08265  19.15424 1.46114   1.000 36.75192  ? 684 HOH A O   1 
HETATM 3334 O O   . HOH H 4 .   ? -16.87661 34.40510 -25.10605 1.000 38.05273  ? 685 HOH A O   1 
HETATM 3335 O O   . HOH H 4 .   ? -11.98525 14.73248 -28.45213 1.000 44.06252  ? 686 HOH A O   1 
HETATM 3336 O O   . HOH H 4 .   ? -7.45671  39.59110 -15.33490 1.000 45.08634  ? 687 HOH A O   1 
HETATM 3337 O O   . HOH H 4 .   ? -24.31640 16.07990 -19.00014 1.000 35.65857  ? 688 HOH A O   1 
HETATM 3338 O O   . HOH H 4 .   ? 1.70832   36.80912 1.63524   1.000 62.28560  ? 689 HOH A O   1 
HETATM 3339 O O   . HOH H 4 .   ? -2.38014  44.64362 -31.99472 1.000 44.35456  ? 690 HOH A O   1 
HETATM 3340 O O   . HOH H 4 .   ? -6.95455  22.16989 -21.27991 1.000 50.19834  ? 691 HOH A O   1 
HETATM 3341 O O   . HOH H 4 .   ? -20.98817 37.73657 -47.80101 1.000 45.54676  ? 692 HOH A O   1 
HETATM 3342 O O   . HOH H 4 .   ? 10.95336  12.04154 -3.72022  1.000 43.96920  ? 693 HOH A O   1 
HETATM 3343 O O   . HOH H 4 .   ? -20.34935 33.53940 -37.92066 1.000 40.00484  ? 694 HOH A O   1 
HETATM 3344 O O   . HOH H 4 .   ? 25.10434  19.32290 -2.30652  1.000 45.19796  ? 695 HOH A O   1 
HETATM 3345 O O   . HOH H 4 .   ? -12.33484 36.95078 -8.60851  1.000 43.33861  ? 696 HOH A O   1 
HETATM 3346 O O   . HOH H 4 .   ? -0.31522  6.68224  0.62648   1.000 59.80048  ? 697 HOH A O   1 
HETATM 3347 O O   . HOH H 4 .   ? -10.97772 42.01122 -4.01813  1.000 70.93575  ? 698 HOH A O   1 
HETATM 3348 O O   . HOH H 4 .   ? 3.93440   24.86715 -28.50253 1.000 61.91139  ? 699 HOH A O   1 
HETATM 3349 O O   . HOH H 4 .   ? -19.04743 11.45283 -28.04817 1.000 39.45508  ? 700 HOH A O   1 
HETATM 3350 O O   . HOH H 4 .   ? -12.59711 13.06226 -25.50671 1.000 58.24518  ? 701 HOH A O   1 
HETATM 3351 O O   . HOH H 4 .   ? -21.02016 21.27902 -20.67225 1.000 33.76225  ? 702 HOH A O   1 
HETATM 3352 O O   . HOH H 4 .   ? 6.94063   32.74542 2.01257   1.000 37.80532  ? 703 HOH A O   1 
HETATM 3353 O O   . HOH H 4 .   ? 2.45717   8.05355  -32.25988 1.000 61.25608  ? 704 HOH A O   1 
HETATM 3354 O O   . HOH H 4 .   ? -17.93406 23.79920 -12.52284 1.000 62.24622  ? 705 HOH A O   1 
HETATM 3355 O O   . HOH H 4 .   ? 10.15545  39.28596 0.32246   1.000 65.15250  ? 706 HOH A O   1 
HETATM 3356 O O   . HOH H 4 .   ? -15.10414 42.94174 -32.01259 1.000 36.50893  ? 707 HOH A O   1 
HETATM 3357 O O   . HOH H 4 .   ? 23.09631  26.83862 -11.53787 1.000 38.56959  ? 708 HOH A O   1 
HETATM 3358 O O   . HOH H 4 .   ? -15.96169 25.53924 -12.37295 1.000 41.35363  ? 709 HOH A O   1 
HETATM 3359 O O   . HOH H 4 .   ? -26.96594 30.06811 -29.53782 1.000 52.15746  ? 710 HOH A O   1 
HETATM 3360 O O   . HOH H 4 .   ? -26.88496 18.91994 -30.30091 1.000 51.49378  ? 711 HOH A O   1 
HETATM 3361 O O   . HOH H 4 .   ? -15.32198 35.43050 -11.47495 1.000 56.66668  ? 712 HOH A O   1 
HETATM 3362 O O   . HOH H 4 .   ? -17.81240 41.28979 -37.55575 1.000 38.23611  ? 713 HOH A O   1 
HETATM 3363 O O   . HOH H 4 .   ? 0.09521   41.21176 -16.44306 1.000 60.36751  ? 714 HOH A O   1 
HETATM 3364 O O   . HOH H 4 .   ? -24.31789 24.61470 -27.43580 1.000 55.94444  ? 715 HOH A O   1 
HETATM 3365 O O   . HOH H 4 .   ? -8.71671  41.24441 -25.38984 1.000 65.30623  ? 716 HOH A O   1 
HETATM 3366 O O   . HOH H 4 .   ? -19.49276 35.00072 -25.73265 1.000 35.92043  ? 717 HOH A O   1 
HETATM 3367 O O   . HOH H 4 .   ? -14.48825 9.23852  -33.51309 1.000 64.45303  ? 718 HOH A O   1 
HETATM 3368 O O   . HOH H 4 .   ? 7.83758   21.65086 -28.05606 1.000 55.34425  ? 719 HOH A O   1 
HETATM 3369 O O   . HOH H 4 .   ? -6.38506  37.73908 -24.69927 1.000 48.67810  ? 720 HOH A O   1 
HETATM 3370 O O   . HOH H 4 .   ? -2.94555  13.31033 0.69844   1.000 43.72016  ? 721 HOH A O   1 
HETATM 3371 O O   . HOH H 4 .   ? -23.86726 39.31082 -45.94268 1.000 65.04841  ? 722 HOH A O   1 
HETATM 3372 O O   . HOH H 4 .   ? 23.14717  17.51591 -2.40877  1.000 42.24710  ? 723 HOH A O   1 
HETATM 3373 O O   . HOH H 4 .   ? -2.95146  -1.40044 -7.76748  1.000 72.84780  ? 724 HOH A O   1 
HETATM 3374 O O   . HOH H 4 .   ? -7.40912  24.69333 -42.47539 1.000 54.98274  ? 725 HOH A O   1 
HETATM 3375 O O   . HOH H 4 .   ? -23.95634 12.26582 -36.94996 1.000 48.13754  ? 726 HOH A O   1 
HETATM 3376 O O   . HOH H 4 .   ? 9.09434   25.14429 -25.23174 1.000 34.28526  ? 727 HOH A O   1 
HETATM 3377 O O   . HOH H 4 .   ? 1.25786   43.60021 -9.55403  1.000 56.06460  ? 728 HOH A O   1 
HETATM 3378 O O   . HOH H 4 .   ? -4.74597  27.46863 -6.99549  1.000 29.52388  ? 729 HOH A O   1 
HETATM 3379 O O   . HOH H 4 .   ? 20.66222  31.76577 -11.07233 1.000 61.71142  ? 730 HOH A O   1 
HETATM 3380 O O   . HOH H 4 .   ? -10.55586 18.56199 -34.44678 1.000 52.69535  ? 731 HOH A O   1 
HETATM 3381 O O   . HOH H 4 .   ? 6.65455   9.48101  -0.26568  1.000 47.91208  ? 732 HOH A O   1 
HETATM 3382 O O   . HOH H 4 .   ? -24.17821 19.96763 -15.82267 1.000 50.39384  ? 733 HOH A O   1 
HETATM 3383 O O   . HOH H 4 .   ? -15.58249 10.44465 -22.17655 1.000 69.37039  ? 734 HOH A O   1 
HETATM 3384 O O   . HOH H 4 .   ? -23.51797 10.05076 -22.34835 1.000 47.01232  ? 735 HOH A O   1 
HETATM 3385 O O   . HOH H 4 .   ? -22.73613 12.97418 -39.85093 1.000 69.11631  ? 736 HOH A O   1 
HETATM 3386 O O   . HOH H 4 .   ? -4.80093  16.50345 -4.31833  1.000 75.38433  ? 737 HOH A O   1 
HETATM 3387 O O   . HOH H 4 .   ? 16.49883  30.37636 -26.94595 1.000 73.51017  ? 738 HOH A O   1 
HETATM 3388 O O   . HOH H 4 .   ? -7.45094  42.02707 -13.52883 1.000 85.34106  ? 739 HOH A O   1 
HETATM 3389 O O   . HOH H 4 .   ? -19.41542 36.93558 -23.60038 1.000 51.09277  ? 740 HOH A O   1 
HETATM 3390 O O   . HOH H 4 .   ? 0.17540   32.26576 -50.07417 1.000 72.13428  ? 741 HOH A O   1 
HETATM 3391 O O   . HOH H 4 .   ? -0.33066  8.29987  -30.60202 1.000 76.55565  ? 742 HOH A O   1 
HETATM 3392 O O   . HOH H 4 .   ? 4.53816   46.92612 -4.62874  1.000 70.12918  ? 743 HOH A O   1 
HETATM 3393 O O   . HOH H 4 .   ? 2.87470   42.41541 -36.56810 1.000 71.91109  ? 744 HOH A O   1 
HETATM 3394 O O   . HOH H 4 .   ? -10.86309 43.10755 0.17691   1.000 65.22388  ? 745 HOH A O   1 
HETATM 3395 O O   . HOH H 4 .   ? -4.36293  44.52522 -1.25853  1.000 65.44411  ? 746 HOH A O   1 
HETATM 3396 O O   . HOH H 4 .   ? -30.35038 25.16439 -30.60533 1.000 59.49985  ? 747 HOH A O   1 
HETATM 3397 O O   . HOH H 4 .   ? 13.86019  26.60011 -28.35891 1.000 65.97441  ? 748 HOH A O   1 
HETATM 3398 O O   . HOH H 4 .   ? 16.25476  28.48172 0.72443   1.000 45.61360  ? 749 HOH A O   1 
HETATM 3399 O O   . HOH H 4 .   ? -18.68031 33.12476 -18.09420 1.000 58.95417  ? 750 HOH A O   1 
HETATM 3400 O O   . HOH H 4 .   ? -15.19129 44.87863 -29.85330 1.000 85.61029  ? 751 HOH A O   1 
HETATM 3401 O O   . HOH H 4 .   ? 22.82813  2.50924  -9.00329  1.000 71.50379  ? 752 HOH A O   1 
HETATM 3402 O O   . HOH H 4 .   ? 3.90534   11.60648 -21.25500 1.000 92.74383  ? 753 HOH A O   1 
HETATM 3403 O O   . HOH H 4 .   ? -7.62918  18.68582 -10.32019 1.000 63.37485  ? 754 HOH A O   1 
HETATM 3404 O O   . HOH H 4 .   ? -9.37609  20.19418 -12.18987 1.000 47.30971  ? 755 HOH A O   1 
HETATM 3405 O O   . HOH H 4 .   ? 13.06717  4.34294  2.32736   1.000 76.68850  ? 756 HOH A O   1 
HETATM 3406 O O   . HOH H 4 .   ? -17.81347 9.43571  -22.11199 1.000 67.75719  ? 757 HOH A O   1 
HETATM 3407 O O   . HOH H 4 .   ? 11.24817  25.92965 4.42105   1.000 74.60094  ? 758 HOH A O   1 
HETATM 3408 O O   . HOH H 4 .   ? -9.20603  41.72960 -9.73548  1.000 64.54688  ? 759 HOH A O   1 
HETATM 3409 O O   . HOH H 4 .   ? 2.29676   22.88511 -28.16423 1.000 73.14442  ? 760 HOH A O   1 
HETATM 3410 O O   . HOH H 4 .   ? 3.22884   38.21536 -41.46559 1.000 73.22975  ? 761 HOH A O   1 
HETATM 3411 O O   . HOH H 4 .   ? 1.70940   9.63347  -34.64546 1.000 79.92678  ? 762 HOH A O   1 
HETATM 3412 O O   . HOH H 4 .   ? 10.88211  0.58695  -1.97639  1.000 94.69348  ? 763 HOH A O   1 
HETATM 3413 O O   . HOH H 4 .   ? 17.48620  27.17918 -22.85507 1.000 64.72359  ? 764 HOH A O   1 
HETATM 3414 O O   . HOH H 4 .   ? -10.40860 43.31485 -27.03526 1.000 48.09942  ? 765 HOH A O   1 
HETATM 3415 O O   . HOH H 4 .   ? -19.78600 8.97818  -28.56476 1.000 67.46347  ? 766 HOH A O   1 
HETATM 3416 O O   . HOH H 4 .   ? 16.02929  12.81367 1.41528   1.000 37.59961  ? 767 HOH A O   1 
HETATM 3417 O O   . HOH H 4 .   ? -3.68119  22.16654 -1.33235  1.000 34.73916  ? 768 HOH A O   1 
HETATM 3418 O O   . HOH H 4 .   ? 14.15462  -4.36390 -6.86131  1.000 76.29379  ? 769 HOH A O   1 
HETATM 3419 O O   . HOH H 4 .   ? 14.16355  12.43918 -0.26397  1.000 63.62250  ? 770 HOH A O   1 
HETATM 3420 O O   . HOH H 4 .   ? -22.47184 18.27408 -43.79486 1.000 76.37446  ? 771 HOH A O   1 
HETATM 3421 O O   . HOH H 4 .   ? -3.24091  3.72224  -6.02590  1.000 76.55879  ? 772 HOH A O   1 
HETATM 3422 O O   . HOH H 4 .   ? -0.897    41.855   -46.273   1.000 65.81011  ? 773 HOH A O   1 
HETATM 3423 O O   . HOH H 4 .   ? 13.239    12.542   -31.516   1.000 67.56232  ? 774 HOH A O   1 
HETATM 3424 O O   . HOH H 4 .   ? -25.00828 17.40080 -16.85791 1.000 40.98852  ? 775 HOH A O   1 
HETATM 3425 O O   . HOH H 4 .   ? -28.24939 38.51460 -38.63349 1.000 77.47497  ? 776 HOH A O   1 
HETATM 3426 O O   . HOH H 4 .   ? 2.20271   18.85286 -27.54521 1.000 76.65919  ? 777 HOH A O   1 
HETATM 3427 O O   . HOH H 4 .   ? 4.10170   45.85619 -8.96493  1.000 72.82999  ? 778 HOH A O   1 
HETATM 3428 O O   . HOH H 4 .   ? 8.31260   10.80162 -2.27322  1.000 51.14083  ? 779 HOH A O   1 
HETATM 3429 O O   . HOH H 4 .   ? 12.30489  12.16107 -1.35504  1.000 79.02317  ? 780 HOH A O   1 
HETATM 3430 O O   . HOH H 4 .   ? 1.12758   -0.56800 -2.96650  1.000 75.69541  ? 781 HOH A O   1 
HETATM 3431 O O   . HOH H 4 .   ? 21.63424  32.82285 -16.36731 1.000 61.67822  ? 782 HOH A O   1 
HETATM 3432 O O   . HOH H 4 .   ? -15.67687 19.52715 -41.47726 1.000 68.90899  ? 783 HOH A O   1 
HETATM 3433 O O   . HOH H 4 .   ? -7.74282  45.92988 -7.71102  1.000 71.61910  ? 784 HOH A O   1 
HETATM 3434 O O   . HOH H 4 .   ? 11.12317  9.83940  0.53949   1.000 69.70554  ? 785 HOH A O   1 
HETATM 3435 O O   . HOH H 4 .   ? -6.66061  12.00457 -14.93523 1.000 58.67136  ? 786 HOH A O   1 
HETATM 3436 O O   . HOH H 4 .   ? -22.85662 12.01825 -18.59074 1.000 71.44666  ? 787 HOH A O   1 
HETATM 3437 O O   . HOH H 4 .   ? 3.44569   41.14217 -31.28941 1.000 77.15931  ? 788 HOH A O   1 
HETATM 3438 O O   . HOH H 4 .   ? 17.93258  32.57429 -29.97744 1.000 58.17067  ? 789 HOH A O   1 
HETATM 3439 O O   . HOH H 4 .   ? -28.70474 19.96993 -40.44432 1.000 67.82882  ? 790 HOH A O   1 
HETATM 3440 O O   . HOH H 4 .   ? 12.81782  44.78908 -13.84400 1.000 77.39972  ? 791 HOH A O   1 
HETATM 3441 O O   . HOH H 4 .   ? -22.07233 34.96520 -50.37689 1.000 71.16976  ? 792 HOH A O   1 
HETATM 3442 O O   . HOH H 4 .   ? 20.21296  4.18821  -23.24307 1.000 68.22311  ? 793 HOH A O   1 
HETATM 3443 O O   . HOH H 4 .   ? 18.97911  7.65567  0.33438   1.000 54.93001  ? 794 HOH A O   1 
HETATM 3444 O O   . HOH H 4 .   ? -6.71110  23.29682 -5.16244  1.000 62.97353  ? 795 HOH A O   1 
HETATM 3445 O O   . HOH H 4 .   ? -1.31103  42.29691 -12.29348 1.000 63.25590  ? 796 HOH A O   1 
HETATM 3446 O O   . HOH H 4 .   ? -17.81200 35.13646 -51.83775 1.000 80.16198  ? 797 HOH A O   1 
HETATM 3447 O O   . HOH H 4 .   ? 9.99206   19.96389 -29.35354 1.000 64.06761  ? 798 HOH A O   1 
HETATM 3448 O O   . HOH H 4 .   ? -15.54925 20.53607 -13.52402 1.000 61.07282  ? 799 HOH A O   1 
HETATM 3449 O O   . HOH H 4 .   ? -9.91343  20.96771 -20.51981 1.000 61.98399  ? 800 HOH A O   1 
HETATM 3450 O O   . HOH H 4 .   ? -12.10224 43.15525 -29.01918 1.000 52.81636  ? 801 HOH A O   1 
HETATM 3451 O O   . HOH H 4 .   ? -9.15828  23.64319 -44.15720 1.000 64.76132  ? 802 HOH A O   1 
HETATM 3452 O O   . HOH H 4 .   ? 18.29849  -1.89094 -6.14115  1.000 75.58920  ? 803 HOH A O   1 
HETATM 3453 O O   . HOH H 4 .   ? -20.08984 24.38472 -13.12830 1.000 50.98695  ? 804 HOH A O   1 
HETATM 3454 O O   . HOH H 4 .   ? 5.03716   28.99394 1.11845   1.000 59.90970  ? 805 HOH A O   1 
HETATM 3455 O O   . HOH H 4 .   ? -0.82705  43.53768 -41.29750 1.000 78.58876  ? 806 HOH A O   1 
HETATM 3456 O O   . HOH H 4 .   ? -2.29663  10.97284 -5.73034  1.000 51.63095  ? 807 HOH A O   1 
HETATM 3457 O O   . HOH H 4 .   ? 3.31099   33.17624 -29.82518 1.000 66.98764  ? 808 HOH A O   1 
HETATM 3458 O O   . HOH H 4 .   ? -5.78942  19.58432 -7.12411  1.000 72.98738  ? 809 HOH A O   1 
HETATM 3459 O O   . HOH H 4 .   ? -2.16468  -3.36177 -5.54539  1.000 75.50572  ? 810 HOH A O   1 
HETATM 3460 O O   . HOH H 4 .   ? -6.39976  19.02105 -34.07305 1.000 69.54128  ? 811 HOH A O   1 
HETATM 3461 O O   . HOH H 4 .   ? -6.23880  32.79852 -2.43153  1.000 41.18702  ? 812 HOH A O   1 
HETATM 3462 O O   . HOH H 4 .   ? 7.53525   45.00942 -14.06839 1.000 73.87108  ? 813 HOH A O   1 
HETATM 3463 O O   . HOH H 4 .   ? -3.33710  8.25094  -28.78072 1.000 77.83760  ? 814 HOH A O   1 
HETATM 3464 O O   . HOH H 4 .   ? -4.04407  30.67730 -33.91382 1.000 48.07235  ? 815 HOH A O   1 
HETATM 3465 O O   . HOH H 4 .   ? -4.46947  15.01965 -0.40214  1.000 47.80572  ? 816 HOH A O   1 
HETATM 3466 O O   . HOH H 4 .   ? -10.45891 37.08500 -5.91927  1.000 74.79258  ? 817 HOH A O   1 
HETATM 3467 O O   . HOH H 4 .   ? 16.69791  7.14314  0.41577   1.000 53.17780  ? 818 HOH A O   1 
HETATM 3468 O O   . HOH H 4 .   ? -14.11207 36.60753 -15.27645 1.000 47.51795  ? 819 HOH A O   1 
HETATM 3469 O O   . HOH H 4 .   ? 4.74690   43.25515 0.94239   1.000 74.29694  ? 820 HOH A O   1 
HETATM 3470 O O   . HOH H 4 .   ? -22.92222 21.90870 -13.26606 1.000 68.50143  ? 821 HOH A O   1 
HETATM 3471 O O   . HOH H 4 .   ? -2.97619  42.62955 -25.93841 1.000 60.56953  ? 822 HOH A O   1 
HETATM 3472 O O   . HOH H 4 .   ? 20.11937  18.29831 -11.88488 1.000 81.81697  ? 823 HOH A O   1 
HETATM 3473 O O   . HOH H 4 .   ? -1.32870  40.13181 1.35164   1.000 64.33509  ? 824 HOH A O   1 
HETATM 3474 O O   . HOH H 4 .   ? -9.97652  40.40906 -19.78256 1.000 62.66939  ? 825 HOH A O   1 
HETATM 3475 O O   . HOH H 4 .   ? 4.61385   8.27654  -36.64341 1.000 79.73084  ? 826 HOH A O   1 
HETATM 3476 O O   . HOH H 4 .   ? -19.72323 42.63636 -34.09192 1.000 68.32933  ? 827 HOH A O   1 
HETATM 3477 O O   . HOH H 4 .   ? -23.17350 44.24193 -49.85492 1.000 81.14643  ? 828 HOH A O   1 
HETATM 3478 O O   . HOH H 4 .   ? -4.56405  21.22946 -5.97080  1.000 42.58036  ? 829 HOH A O   1 
HETATM 3479 O O   . HOH H 4 .   ? -3.34698  4.67327  -13.58700 1.000 69.11937  ? 830 HOH A O   1 
HETATM 3480 O O   . HOH H 4 .   ? 12.54562  1.78545  -3.56540  1.000 54.24512  ? 831 HOH A O   1 
HETATM 3481 O O   . HOH H 4 .   ? 13.08346  23.97493 -26.59475 1.000 73.62089  ? 832 HOH A O   1 
HETATM 3482 O O   . HOH H 4 .   ? 3.31704   18.45119 -29.74172 1.000 80.35392  ? 833 HOH A O   1 
HETATM 3483 O O   . HOH H 4 .   ? 3.00641   40.62887 -33.56414 1.000 72.76014  ? 834 HOH A O   1 
HETATM 3484 O O   . HOH H 4 .   ? -6.28758  26.14450 -5.00974  1.000 46.08566  ? 835 HOH A O   1 
HETATM 3485 O O   . HOH H 4 .   ? 14.16832  30.91040 2.60710   1.000 70.73122  ? 836 HOH A O   1 
HETATM 3486 O O   . HOH H 4 .   ? 17.061    -4.637   -10.400   1.000 74.62891  ? 837 HOH A O   1 
HETATM 3487 O O   . HOH H 4 .   ? 23.55747  31.54110 -13.48632 1.000 62.29923  ? 838 HOH A O   1 
HETATM 3488 O O   . HOH H 4 .   ? 26.84128  18.59600 -0.09101  1.000 42.03718  ? 839 HOH A O   1 
HETATM 3489 O O   . HOH H 4 .   ? 19.50145  22.32124 3.71447   1.000 33.05225  ? 840 HOH A O   1 
HETATM 3490 O O   . HOH H 4 .   ? 6.73076   20.93731 0.48832   1.000 52.27838  ? 841 HOH A O   1 
HETATM 3491 O O   . HOH H 4 .   ? 13.70848  7.69906  1.00426   1.000 74.25330  ? 842 HOH A O   1 
HETATM 3492 O O   . HOH H 4 .   ? 9.69306   32.23243 2.68252   1.000 61.65698  ? 843 HOH A O   1 
HETATM 3493 O O   . HOH H 4 .   ? -22.95749 33.36714 -38.50227 1.000 74.40767  ? 844 HOH A O   1 
HETATM 3494 O O   . HOH H 4 .   ? 4.07526   47.76929 -7.90908  1.000 106.16306 ? 845 HOH A O   1 
HETATM 3495 O O   . HOH H 4 .   ? 15.12281  21.18765 2.81875   1.000 58.01219  ? 846 HOH A O   1 
HETATM 3496 O O   . HOH H 4 .   ? -15.69332 34.52467 -54.50854 1.000 73.78059  ? 847 HOH A O   1 
HETATM 3497 O O   . HOH H 4 .   ? 10.93891  19.21435 0.08551   1.000 79.55550  ? 848 HOH A O   1 
HETATM 3498 O O   . HOH H 4 .   ? 3.32284   38.75850 -0.09096  1.000 47.49013  ? 849 HOH A O   1 
HETATM 3499 O O   . HOH H 4 .   ? 19.71601  34.03442 -10.66985 1.000 65.18252  ? 850 HOH A O   1 
HETATM 3500 O O   . HOH H 4 .   ? 19.50240  4.39212  -12.31240 1.000 58.42848  ? 851 HOH A O   1 
HETATM 3501 O O   . HOH H 4 .   ? -18.04398 43.27840 -39.34057 1.000 37.25154  ? 852 HOH A O   1 
HETATM 3502 O O   . HOH H 4 .   ? -15.39274 36.30676 -9.16551  1.000 62.07714  ? 853 HOH A O   1 
HETATM 3503 O O   . HOH H 4 .   ? 5.41598   38.11039 1.70557   1.000 56.37527  ? 854 HOH A O   1 
HETATM 3504 O O   . HOH H 4 .   ? -9.42095  38.51714 -22.53796 1.000 58.31639  ? 855 HOH A O   1 
HETATM 3505 O O   . HOH H 4 .   ? 19.77445  23.12756 -13.93829 1.000 43.90163  ? 856 HOH A O   1 
HETATM 3506 O O   . HOH H 4 .   ? -0.11274  -8.25222 -5.78677  1.000 83.68466  ? 857 HOH A O   1 
HETATM 3507 O O   . HOH H 4 .   ? 21.53871  5.97085  -8.26009  1.000 63.40813  ? 858 HOH A O   1 
HETATM 3508 O O   . HOH H 4 .   ? 6.66048   13.60028 -0.15829  1.000 58.78872  ? 859 HOH A O   1 
HETATM 3509 O O   . HOH H 4 .   ? -28.75211 17.83592 -32.02578 1.000 44.25960  ? 860 HOH A O   1 
HETATM 3510 O O   . HOH H 4 .   ? -28.07522 13.59130 -35.07184 1.000 65.89805  ? 861 HOH A O   1 
HETATM 3511 O O   . HOH H 4 .   ? 22.45983  9.74614  -10.15904 1.000 66.01260  ? 862 HOH A O   1 
HETATM 3512 O O   . HOH H 4 .   ? -19.39200 37.59965 -36.93507 1.000 65.32543  ? 863 HOH A O   1 
HETATM 3513 O O   . HOH H 4 .   ? -22.05490 25.96339 -14.27975 1.000 40.08221  ? 864 HOH A O   1 
HETATM 3514 O O   . HOH H 4 .   ? 10.66776  37.19465 -32.23197 1.000 84.77749  ? 865 HOH A O   1 
HETATM 3515 O O   . HOH H 4 .   ? 22.84593  12.97956 -4.16797  1.000 58.42605  ? 866 HOH A O   1 
HETATM 3516 O O   . HOH H 4 .   ? 15.91174  35.56764 1.62150   1.000 48.16425  ? 867 HOH A O   1 
HETATM 3517 O O   . HOH H 4 .   ? -2.78291  5.87986  -0.88515  1.000 52.61058  ? 868 HOH A O   1 
HETATM 3518 O O   . HOH H 4 .   ? -8.38353  29.67982 -6.25567  1.000 50.88121  ? 869 HOH A O   1 
HETATM 3519 O O   . HOH H 4 .   ? -13.36968 30.07823 -6.96729  1.000 56.64158  ? 870 HOH A O   1 
HETATM 3520 O O   . HOH H 4 .   ? 15.37543  24.17588 -25.70768 1.000 57.25590  ? 871 HOH A O   1 
HETATM 3521 O O   . HOH H 4 .   ? -28.44944 22.23196 -26.53171 1.000 46.08070  ? 872 HOH A O   1 
HETATM 3522 O O   . HOH H 4 .   ? 23.01941  14.73990 -2.16954  1.000 60.04043  ? 873 HOH A O   1 
HETATM 3523 O O   . HOH H 4 .   ? -29.77515 25.75401 -35.50367 1.000 60.27533  ? 874 HOH A O   1 
HETATM 3524 O O   . HOH H 4 .   ? -4.96673  18.24073 -3.13550  1.000 42.41287  ? 875 HOH A O   1 
HETATM 3525 O O   . HOH H 4 .   ? -29.71221 28.75913 -34.54488 1.000 71.99502  ? 876 HOH A O   1 
HETATM 3526 O O   . HOH H 4 .   ? -23.37404 9.61809  -37.09403 1.000 66.05486  ? 877 HOH A O   1 
HETATM 3527 O O   . HOH H 4 .   ? -11.81485 39.60492 -9.07117  1.000 70.08213  ? 878 HOH A O   1 
HETATM 3528 O O   . HOH H 4 .   ? 10.23443  18.46754 -30.72862 1.000 71.68326  ? 879 HOH A O   1 
HETATM 3529 O O   . HOH H 4 .   ? -28.50041 20.46319 -28.73491 1.000 41.56521  ? 880 HOH A O   1 
HETATM 3530 O O   . HOH H 4 .   ? 0.32998   32.93796 3.51738   1.000 63.72872  ? 881 HOH A O   1 
HETATM 3531 O O   . HOH H 4 .   ? 13.95411  22.17430 -28.56918 1.000 70.07936  ? 882 HOH A O   1 
HETATM 3532 O O   . HOH H 4 .   ? 11.76786  15.72709 0.06279   1.000 75.87001  ? 883 HOH A O   1 
HETATM 3533 O O   . HOH H 4 .   ? 14.62955  39.20252 -0.41841  1.000 59.54077  ? 884 HOH A O   1 
HETATM 3534 O O   . HOH H 4 .   ? 3.66295   26.72851 1.39643   1.000 63.13284  ? 885 HOH A O   1 
HETATM 3535 O O   . HOH H 4 .   ? -22.88005 41.17840 -30.26834 1.000 80.86922  ? 886 HOH A O   1 
HETATM 3536 O O   . HOH H 4 .   ? 18.62810  6.53494  -11.07723 1.000 52.49485  ? 887 HOH A O   1 
HETATM 3537 O O   . HOH H 4 .   ? -11.13327 28.90505 -6.04155  1.000 62.25034  ? 888 HOH A O   1 
HETATM 3538 O O   . HOH H 4 .   ? -12.47206 51.25499 -27.00147 1.000 73.09788  ? 889 HOH A O   1 
HETATM 3539 O O   . HOH H 4 .   ? 20.645    -1.697   -11.535   1.000 74.95139  ? 890 HOH A O   1 
HETATM 3540 O O   . HOH H 4 .   ? -19.13561 40.49068 -19.49537 1.000 71.82640  ? 891 HOH A O   1 
HETATM 3541 O O   . HOH H 4 .   ? -1.17612  8.35485  -33.50916 1.000 76.92286  ? 892 HOH A O   1 
HETATM 3542 O O   . HOH H 4 .   ? 1.02753   30.99781 -35.07379 1.000 75.30486  ? 893 HOH A O   1 
HETATM 3543 O O   . HOH H 4 .   ? -4.16539  7.58427  -2.66306  1.000 48.26417  ? 894 HOH A O   1 
HETATM 3544 O O   . HOH H 4 .   ? 13.52249  16.26592 2.17792   1.000 70.25578  ? 895 HOH A O   1 
HETATM 3545 O O   . HOH H 4 .   ? 3.22240   38.40261 -38.48116 1.000 67.44563  ? 896 HOH A O   1 
HETATM 3546 O O   . HOH H 4 .   ? 2.84151   33.20148 -49.03081 1.000 76.74931  ? 897 HOH A O   1 
HETATM 3547 O O   . HOH H 4 .   ? -8.00368  28.66389 -3.68688  1.000 62.20546  ? 898 HOH A O   1 
HETATM 3548 O O   . HOH H 4 .   ? 1.27592   47.50083 -9.54129  1.000 78.23634  ? 899 HOH A O   1 
HETATM 3549 O O   . HOH H 4 .   ? -3.32623  47.59895 -27.92371 1.000 63.39433  ? 900 HOH A O   1 
HETATM 3550 O O   . HOH H 4 .   ? 25.00821  13.67827 -5.22924  1.000 75.52460  ? 901 HOH A O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . GLU A 4   ? 1.02022 1.04590 0.92709 0.09863  0.05637  -0.02797 4   GLU A N   
2    C CA  . GLU A 4   ? 0.96261 1.03585 0.92769 0.10912  0.02173  -0.03166 4   GLU A CA  
3    C C   . GLU A 4   ? 0.74687 0.89382 0.85577 0.02091  0.06817  -0.00173 4   GLU A C   
4    O O   . GLU A 4   ? 0.76879 0.86403 0.85177 0.06431  0.10551  0.01492  4   GLU A O   
5    C CB  . GLU A 4   ? 0.99469 1.17333 0.97362 0.19616  -0.04988 -0.02950 4   GLU A CB  
6    C CG  . GLU A 4   ? 1.10674 1.30896 1.01196 0.18739  -0.09901 -0.03259 4   GLU A CG  
7    C CD  . GLU A 4   ? 1.20527 1.42469 1.05243 0.17061  -0.09934 -0.03263 4   GLU A CD  
8    O OE1 . GLU A 4   ? 1.24262 1.47094 1.07621 0.16707  -0.10133 -0.04422 4   GLU A OE1 
9    O OE2 . GLU A 4   ? 1.19056 1.45494 1.05765 0.15561  -0.11206 -0.02406 4   GLU A OE2 
10   N N   . ARG A 5   ? 0.62154 0.78244 0.78169 -0.01641 0.05734  0.03520  5   ARG A N   
11   C CA  . ARG A 5   ? 0.59782 0.69161 0.71542 0.01178  0.07431  0.05068  5   ARG A CA  
12   C C   . ARG A 5   ? 0.53216 0.59931 0.66928 0.00141  0.01070  0.05734  5   ARG A C   
13   O O   . ARG A 5   ? 0.51992 0.60821 0.70129 0.08101  -0.00462 0.08674  5   ARG A O   
14   C CB  . ARG A 5   ? 0.71686 0.75196 0.72982 0.02228  0.03911  0.07136  5   ARG A CB  
15   C CG  . ARG A 5   ? 0.70442 0.76863 0.72092 0.01084  0.04118  0.04841  5   ARG A CG  
16   C CD  . ARG A 5   ? 0.65814 0.74876 0.68336 0.02834  -0.01589 0.00660  5   ARG A CD  
17   N NE  . ARG A 5   ? 0.57445 0.73809 0.65676 0.07773  -0.08716 0.01570  5   ARG A NE  
18   C CZ  . ARG A 5   ? 0.67619 0.77471 0.69264 0.12497  -0.15631 0.04211  5   ARG A CZ  
19   N NH1 . ARG A 5   ? 0.76453 0.77641 0.69331 0.23510  -0.19675 0.07967  5   ARG A NH1 
20   N NH2 . ARG A 5   ? 0.66860 0.72904 0.70369 0.08071  -0.15636 0.08934  5   ARG A NH2 
21   N N   . PRO A 6   ? 0.51036 0.57872 0.59677 -0.01093 0.05026  0.06238  6   PRO A N   
22   C CA  . PRO A 6   ? 0.43539 0.57675 0.55608 -0.11701 0.01449  0.06527  6   PRO A CA  
23   C C   . PRO A 6   ? 0.46262 0.51445 0.52003 -0.09785 -0.01113 0.06739  6   PRO A C   
24   O O   . PRO A 6   ? 0.53850 0.43899 0.48517 -0.05856 -0.02813 0.07656  6   PRO A O   
25   C CB  . PRO A 6   ? 0.40984 0.58871 0.54275 -0.04120 0.08783  0.08676  6   PRO A CB  
26   C CG  . PRO A 6   ? 0.50761 0.51491 0.56515 -0.09131 -0.00607 0.07065  6   PRO A CG  
27   C CD  . PRO A 6   ? 0.54838 0.50409 0.56680 -0.01969 0.03062  0.10064  6   PRO A CD  
28   N N   . THR A 7   ? 0.44650 0.46831 0.49048 0.00781  0.02490  0.05418  7   THR A N   
29   C CA  . THR A 7   ? 0.49683 0.43606 0.44473 0.00856  0.01379  0.06758  7   THR A CA  
30   C C   . THR A 7   ? 0.56875 0.35982 0.39958 -0.00278 -0.03895 0.05606  7   THR A C   
31   O O   . THR A 7   ? 0.53136 0.42391 0.40107 0.04558  -0.01773 0.06415  7   THR A O   
32   C CB  . THR A 7   ? 0.50657 0.44919 0.44444 0.09640  0.00845  0.08841  7   THR A CB  
33   O OG1 . THR A 7   ? 0.55541 0.46098 0.47193 -0.06661 -0.04454 0.09197  7   THR A OG1 
34   C CG2 . THR A 7   ? 0.54077 0.48735 0.40937 0.03481  0.02505  0.08172  7   THR A CG2 
35   N N   . PHE A 8   ? 0.60652 0.30987 0.36853 -0.06229 0.02414  -0.03821 8   PHE A N   
36   C CA  . PHE A 8   ? 0.61561 0.34215 0.39416 -0.04358 -0.01285 0.02142  8   PHE A CA  
37   C C   . PHE A 8   ? 0.69759 0.40899 0.37583 0.04895  -0.02822 0.09895  8   PHE A C   
38   O O   . PHE A 8   ? 0.73196 0.46074 0.36861 -0.02925 -0.02360 0.09244  8   PHE A O   
39   C CB  . PHE A 8   ? 0.64682 0.38843 0.40448 -0.06878 -0.06502 0.05846  8   PHE A CB  
40   C CG  . PHE A 8   ? 0.53168 0.43848 0.39999 -0.04096 0.00407  0.05700  8   PHE A CG  
41   C CD1 . PHE A 8   ? 0.61656 0.44243 0.40116 -0.02977 -0.02071 0.04394  8   PHE A CD1 
42   C CD2 . PHE A 8   ? 0.44691 0.38585 0.40328 -0.00978 -0.01520 0.06649  8   PHE A CD2 
43   C CE1 . PHE A 8   ? 0.53835 0.40669 0.42133 -0.10876 -0.06160 0.04037  8   PHE A CE1 
44   C CE2 . PHE A 8   ? 0.53296 0.35611 0.39961 -0.01442 -0.01564 0.05054  8   PHE A CE2 
45   C CZ  . PHE A 8   ? 0.52806 0.39439 0.40070 -0.01992 0.00172  0.04027  8   PHE A CZ  
46   N N   . TYR A 9   ? 0.62606 0.40488 0.38446 0.03885  -0.00730 0.07765  9   TYR A N   
47   C CA  . TYR A 9   ? 0.61313 0.37987 0.38244 0.00220  0.05227  0.10570  9   TYR A CA  
48   C C   . TYR A 9   ? 0.64868 0.38163 0.39336 0.01918  0.05174  0.11983  9   TYR A C   
49   O O   . TYR A 9   ? 0.77715 0.32448 0.37177 -0.03667 0.02284  0.10966  9   TYR A O   
50   C CB  . TYR A 9   ? 0.54845 0.36971 0.37704 -0.01196 -0.04951 0.10043  9   TYR A CB  
51   C CG  . TYR A 9   ? 0.62371 0.35553 0.39597 -0.02348 -0.02127 0.08139  9   TYR A CG  
52   C CD1 . TYR A 9   ? 0.58604 0.33122 0.40519 0.03265  -0.05604 0.07364  9   TYR A CD1 
53   C CD2 . TYR A 9   ? 0.75792 0.36469 0.40448 -0.00012 -0.01026 0.09064  9   TYR A CD2 
54   C CE1 . TYR A 9   ? 0.59678 0.33450 0.40185 -0.03407 0.02012  0.11141  9   TYR A CE1 
55   C CE2 . TYR A 9   ? 0.64612 0.37782 0.41132 -0.02939 0.00853  0.06760  9   TYR A CE2 
56   C CZ  . TYR A 9   ? 0.60435 0.39640 0.43653 -0.03752 -0.01159 0.06629  9   TYR A CZ  
57   O OH  . TYR A 9   ? 0.52166 0.43492 0.44216 0.04118  0.02283  0.05194  9   TYR A OH  
58   N N   . ARG A 10  ? 0.75386 0.44387 0.39396 -0.00189 0.08636  0.09052  10  ARG A N   
59   C CA  . ARG A 10  ? 0.78714 0.51096 0.48033 -0.01633 0.04332  0.10711  10  ARG A CA  
60   C C   . ARG A 10  ? 0.80732 0.52347 0.51042 0.05054  0.16623  0.09966  10  ARG A C   
61   O O   . ARG A 10  ? 1.06417 0.55306 0.50569 0.01057  0.20991  0.11532  10  ARG A O   
62   C CB  . ARG A 10  ? 0.93063 0.65585 0.54520 -0.04599 0.02768  0.08129  10  ARG A CB  
63   C CG  . ARG A 10  ? 1.08831 0.76326 0.62060 -0.13074 0.00911  0.06438  10  ARG A CG  
64   C CD  . ARG A 10  ? 1.21666 0.84629 0.70315 -0.10397 -0.03348 0.02020  10  ARG A CD  
65   N NE  . ARG A 10  ? 1.29809 0.94721 0.77814 -0.04947 -0.07176 -0.01916 10  ARG A NE  
66   C CZ  . ARG A 10  ? 1.36229 1.02954 0.84668 -0.00455 -0.09464 -0.02031 10  ARG A CZ  
67   N NH1 . ARG A 10  ? 1.40502 1.05905 0.87986 0.02732  -0.10819 -0.01447 10  ARG A NH1 
68   N NH2 . ARG A 10  ? 1.36975 1.02330 0.87025 0.01017  -0.10338 -0.02638 10  ARG A NH2 
69   N N   . GLN A 11  ? 0.68895 0.59327 0.56931 0.04411  0.20464  0.11672  11  GLN A N   
70   C CA  . GLN A 11  ? 0.66080 0.65370 0.69635 -0.00440 0.18535  0.11870  11  GLN A CA  
71   C C   . GLN A 11  ? 0.73065 0.61574 0.73909 0.00241  0.17371  0.14644  11  GLN A C   
72   O O   . GLN A 11  ? 0.76032 0.55093 0.69551 0.05113  0.22413  0.12178  11  GLN A O   
73   C CB  . GLN A 11  ? 0.56212 0.71596 0.76476 -0.09366 0.23873  0.10081  11  GLN A CB  
74   C CG  . GLN A 11  ? 0.79852 0.78958 0.82788 0.01020  0.15479  0.06172  11  GLN A CG  
75   C CD  . GLN A 11  ? 0.97002 0.82714 0.86169 0.06999  0.15299  0.06892  11  GLN A CD  
76   O OE1 . GLN A 11  ? 1.02227 0.81793 0.88561 0.09706  0.11730  0.06739  11  GLN A OE1 
77   N NE2 . GLN A 11  ? 1.08394 0.81502 0.85804 0.10116  0.14781  0.09710  11  GLN A NE2 
78   N N   . GLU A 12  ? 0.79211 0.69482 0.76980 -0.02084 0.22407  0.14113  12  GLU A N   
79   C CA  . GLU A 12  ? 0.93179 0.79552 0.87610 0.00741  0.19378  0.10828  12  GLU A CA  
80   C C   . GLU A 12  ? 0.96418 0.90081 0.99344 0.04118  0.17073  0.01302  12  GLU A C   
81   O O   . GLU A 12  ? 1.10943 0.98943 1.02550 0.02040  0.15555  0.00011  12  GLU A O   
82   C CB  . GLU A 12  ? 1.06192 0.83892 0.91001 -0.02008 0.17547  0.14756  12  GLU A CB  
83   C CG  . GLU A 12  ? 1.22588 0.86502 0.95374 -0.07274 0.13285  0.19206  12  GLU A CG  
84   C CD  . GLU A 12  ? 1.31369 0.88740 0.98690 -0.04547 0.14150  0.21285  12  GLU A CD  
85   O OE1 . GLU A 12  ? 1.23289 0.88505 1.00666 -0.00707 0.11142  0.18279  12  GLU A OE1 
86   O OE2 . GLU A 12  ? 1.44512 0.93211 0.98998 -0.05261 0.14204  0.22165  12  GLU A OE2 
87   N N   . LEU A 13  ? 0.91731 0.94305 1.06051 0.11482  0.16708  -0.02854 13  LEU A N   
88   C CA  . LEU A 13  ? 1.04678 0.99742 1.10129 0.15456  0.10408  -0.04832 13  LEU A CA  
89   C C   . LEU A 13  ? 1.35228 1.06058 1.13881 0.21261  0.12512  -0.05843 13  LEU A C   
90   O O   . LEU A 13  ? 1.50496 1.08307 1.16787 0.23769  0.13512  -0.07512 13  LEU A O   
91   C CB  . LEU A 13  ? 0.97650 0.95189 1.09095 0.07415  0.01231  -0.05023 13  LEU A CB  
92   C CG  . LEU A 13  ? 0.95086 0.88753 1.10248 -0.02955 -0.05445 -0.05666 13  LEU A CG  
93   C CD1 . LEU A 13  ? 0.99140 0.85586 1.10279 -0.08541 -0.01225 -0.04939 13  LEU A CD1 
94   C CD2 . LEU A 13  ? 0.96492 0.87000 1.12525 -0.13034 -0.05560 -0.08084 13  LEU A CD2 
95   N N   . ASN A 14  ? 1.41302 1.08431 1.14160 0.23522  0.16039  -0.03339 14  ASN A N   
96   C CA  . ASN A 14  ? 1.40257 1.10817 1.17253 0.20503  0.19480  -0.02847 14  ASN A CA  
97   C C   . ASN A 14  ? 1.23070 1.10957 1.17446 0.19085  0.27562  -0.02833 14  ASN A C   
98   O O   . ASN A 14  ? 1.07067 1.11775 1.16698 0.26424  0.46400  -0.04115 14  ASN A O   
99   C CB  . ASN A 14  ? 1.46597 1.15216 1.21466 0.22974  0.16753  -0.00351 14  ASN A CB  
100  C CG  . ASN A 14  ? 1.46731 1.18173 1.26692 0.24704  0.16944  0.04232  14  ASN A CG  
101  O OD1 . ASN A 14  ? 1.32587 1.19264 1.29046 0.29387  0.23719  0.03209  14  ASN A OD1 
102  N ND2 . ASN A 14  ? 1.56828 1.21157 1.28317 0.22115  0.14520  0.06116  14  ASN A ND2 
103  N N   . LYS A 15  ? 1.09485 1.08382 1.15714 0.14209  0.19048  -0.05213 15  LYS A N   
104  C CA  . LYS A 15  ? 0.97784 1.03181 1.09985 0.17139  0.16031  -0.09833 15  LYS A CA  
105  C C   . LYS A 15  ? 0.93226 0.92574 0.96811 0.14507  0.14247  -0.10492 15  LYS A C   
106  O O   . LYS A 15  ? 0.92926 0.89431 0.95003 0.23938  0.13338  -0.16931 15  LYS A O   
107  C CB  . LYS A 15  ? 1.03923 1.09599 1.16592 0.13741  0.12666  -0.08353 15  LYS A CB  
108  C CG  . LYS A 15  ? 1.11365 1.14489 1.22623 0.06094  0.07788  -0.06257 15  LYS A CG  
109  C CD  . LYS A 15  ? 1.15132 1.18577 1.28026 0.02279  0.06608  -0.04203 15  LYS A CD  
110  C CE  . LYS A 15  ? 1.19176 1.20977 1.31525 -0.01757 0.06443  -0.02609 15  LYS A CE  
111  N NZ  . LYS A 15  ? 1.21751 1.21600 1.33146 -0.04134 0.05339  -0.00990 15  LYS A NZ  
112  N N   A THR A 16  ? 0.87758 0.86150 0.90736 0.10692  0.16714  -0.08559 16  THR A N   
113  N N   B THR A 16  ? 0.88090 0.87416 0.90998 0.15440  0.16437  -0.05114 16  THR A N   
114  C CA  A THR A 16  ? 0.88167 0.79573 0.82738 0.08959  0.20396  -0.07626 16  THR A CA  
115  C CA  B THR A 16  ? 0.89087 0.81586 0.83328 0.18470  0.20152  -0.01675 16  THR A CA  
116  C C   A THR A 16  ? 0.88377 0.71364 0.75922 0.05756  0.21796  -0.05675 16  THR A C   
117  C C   B THR A 16  ? 0.88336 0.72590 0.76407 0.09894  0.21693  -0.02360 16  THR A C   
118  O O   A THR A 16  ? 0.89088 0.67689 0.72800 0.09830  0.29701  -0.06666 16  THR A O   
119  O O   B THR A 16  ? 0.87506 0.68635 0.73509 0.13333  0.29356  -0.02575 16  THR A O   
120  C CB  A THR A 16  ? 0.95999 0.80445 0.81591 0.06487  0.20492  -0.07077 16  THR A CB  
121  C CB  B THR A 16  ? 0.98228 0.84367 0.82527 0.23704  0.19423  0.04083  16  THR A CB  
122  O OG1 A THR A 16  ? 0.89916 0.79579 0.81274 0.00528  0.18350  -0.06965 16  THR A OG1 
123  O OG1 B THR A 16  ? 1.07455 0.84042 0.80659 0.29585  0.21325  0.06560  16  THR A OG1 
124  C CG2 A THR A 16  ? 1.04058 0.78204 0.80175 0.08197  0.23614  -0.08364 16  THR A CG2 
125  C CG2 B THR A 16  ? 0.89912 0.86619 0.82781 0.20958  0.17136  0.06534  16  THR A CG2 
126  N N   . ILE A 17  ? 0.82942 0.68790 0.73098 0.08593  0.18341  -0.01985 17  ILE A N   
127  C CA  . ILE A 17  ? 0.73211 0.67264 0.69336 0.02064  0.14642  0.00016  17  ILE A CA  
128  C C   . ILE A 17  ? 0.67151 0.63835 0.62554 0.04235  0.13614  0.08261  17  ILE A C   
129  O O   . ILE A 17  ? 0.71398 0.64035 0.61613 0.08560  0.23077  0.07730  17  ILE A O   
130  C CB  . ILE A 17  ? 0.78990 0.70583 0.74109 -0.01134 0.14504  -0.04053 17  ILE A CB  
131  C CG1 . ILE A 17  ? 0.77599 0.67621 0.71756 -0.05624 0.19971  -0.05737 17  ILE A CG1 
132  C CG2 . ILE A 17  ? 0.81745 0.70672 0.76657 -0.01939 0.10536  -0.06833 17  ILE A CG2 
133  C CD1 . ILE A 17  ? 0.75682 0.70749 0.71881 -0.00044 0.23903  -0.05770 17  ILE A CD1 
134  N N   . TRP A 18  ? 0.61172 0.53527 0.53555 -0.00415 0.09168  0.08856  18  TRP A N   
135  C CA  . TRP A 18  ? 0.54443 0.47172 0.50383 0.05127  0.05704  0.07030  18  TRP A CA  
136  C C   . TRP A 18  ? 0.55348 0.41975 0.45100 -0.02672 0.04967  0.07755  18  TRP A C   
137  O O   . TRP A 18  ? 0.63687 0.50474 0.43772 -0.01342 0.02510  0.12059  18  TRP A O   
138  C CB  . TRP A 18  ? 0.47871 0.54220 0.49110 0.11175  0.10487  0.00525  18  TRP A CB  
139  C CG  . TRP A 18  ? 0.66698 0.60617 0.49944 0.14069  0.10780  -0.03386 18  TRP A CG  
140  C CD1 . TRP A 18  ? 0.82285 0.71017 0.53616 0.20099  0.08872  -0.01232 18  TRP A CD1 
141  C CD2 . TRP A 18  ? 0.59016 0.57585 0.50261 0.09385  0.14115  -0.00866 18  TRP A CD2 
142  N NE1 . TRP A 18  ? 0.78496 0.68952 0.53360 0.23224  0.10306  0.00747  18  TRP A NE1 
143  C CE2 . TRP A 18  ? 0.70581 0.60517 0.52402 0.14855  0.10560  0.01955  18  TRP A CE2 
144  C CE3 . TRP A 18  ? 0.49144 0.52787 0.49790 -0.03466 0.08389  -0.00749 18  TRP A CE3 
145  C CZ2 . TRP A 18  ? 0.58040 0.51377 0.50360 0.05492  0.11603  -0.04471 18  TRP A CZ2 
146  C CZ3 . TRP A 18  ? 0.52833 0.52904 0.48812 -0.03574 0.08757  -0.07262 18  TRP A CZ3 
147  C CH2 . TRP A 18  ? 0.47358 0.51068 0.49847 -0.00742 0.05543  -0.02191 18  TRP A CH2 
148  N N   . GLU A 19  ? 0.55293 0.33937 0.38699 -0.02117 0.03513  0.04832  19  GLU A N   
149  C CA  . GLU A 19  ? 0.53079 0.42591 0.39426 -0.02683 0.04919  0.05850  19  GLU A CA  
150  C C   . GLU A 19  ? 0.47833 0.41260 0.35313 0.04407  0.01455  0.02793  19  GLU A C   
151  O O   . GLU A 19  ? 0.47968 0.42641 0.35991 0.02604  0.04504  0.05224  19  GLU A O   
152  C CB  . GLU A 19  ? 0.60300 0.51207 0.44555 -0.06108 0.01640  0.06236  19  GLU A CB  
153  C CG  . GLU A 19  ? 0.86201 0.61184 0.48046 -0.14738 -0.05195 0.04241  19  GLU A CG  
154  C CD  . GLU A 19  ? 1.09563 0.71496 0.51711 -0.07032 -0.08398 0.03099  19  GLU A CD  
155  O OE1 . GLU A 19  ? 1.27724 0.68344 0.50077 -0.04366 -0.03779 0.09849  19  GLU A OE1 
156  O OE2 . GLU A 19  ? 0.93579 0.75344 0.56050 -0.06846 -0.16911 0.00425  19  GLU A OE2 
157  N N   . VAL A 20  ? 0.52022 0.28316 0.32739 0.00843  0.01611  -0.02038 20  VAL A N   
158  C CA  . VAL A 20  ? 0.47364 0.26170 0.36242 0.04223  0.02233  -0.02661 20  VAL A CA  
159  C C   . VAL A 20  ? 0.42832 0.30852 0.36181 0.02842  0.05323  -0.00926 20  VAL A C   
160  O O   . VAL A 20  ? 0.56960 0.40320 0.34738 -0.03310 -0.02923 0.02978  20  VAL A O   
161  C CB  . VAL A 20  ? 0.52122 0.23316 0.40039 -0.00455 0.04883  0.07208  20  VAL A CB  
162  C CG1 . VAL A 20  ? 0.49447 0.21320 0.39724 -0.00468 0.00111  0.05650  20  VAL A CG1 
163  C CG2 . VAL A 20  ? 0.60438 0.27443 0.45552 -0.03613 0.08452  0.07579  20  VAL A CG2 
164  N N   . PRO A 21  ? 0.46055 0.36858 0.34286 -0.03968 -0.01895 0.05825  21  PRO A N   
165  C CA  . PRO A 21  ? 0.44480 0.33103 0.33617 -0.03500 0.01600  0.07691  21  PRO A CA  
166  C C   . PRO A 21  ? 0.39397 0.37103 0.38747 -0.05114 0.02278  0.04011  21  PRO A C   
167  O O   . PRO A 21  ? 0.37937 0.37205 0.43637 0.00690  0.00331  0.04962  21  PRO A O   
168  C CB  . PRO A 21  ? 0.43183 0.33179 0.34275 -0.00905 -0.02257 0.12151  21  PRO A CB  
169  C CG  . PRO A 21  ? 0.45630 0.41740 0.30104 -0.01930 -0.00326 0.11894  21  PRO A CG  
170  C CD  . PRO A 21  ? 0.42859 0.46395 0.32227 -0.03695 0.01423  0.04125  21  PRO A CD  
171  N N   A GLU A 22  ? 0.45839 0.36651 0.38969 -0.01553 0.00724  0.05059  22  GLU A N   
172  N N   B GLU A 22  ? 0.51190 0.38042 0.35801 -0.04009 0.00543  0.05021  22  GLU A N   
173  C CA  A GLU A 22  ? 0.42305 0.35960 0.39447 0.03004  -0.02477 0.06862  22  GLU A CA  
174  C CA  B GLU A 22  ? 0.42093 0.33789 0.36832 0.03292  -0.07736 0.08565  22  GLU A CA  
175  C C   A GLU A 22  ? 0.45698 0.36903 0.36401 0.03894  -0.03160 0.06272  22  GLU A C   
176  C C   B GLU A 22  ? 0.51292 0.33828 0.36515 0.02430  0.00959  0.06006  22  GLU A C   
177  O O   A GLU A 22  ? 0.51483 0.34997 0.33737 0.04638  -0.09793 0.07374  22  GLU A O   
178  O O   B GLU A 22  ? 0.61122 0.31052 0.36107 -0.01823 -0.02483 0.02924  22  GLU A O   
179  C CB  A GLU A 22  ? 0.45467 0.36778 0.42024 0.02579  -0.00193 0.08353  22  GLU A CB  
180  C CB  B GLU A 22  ? 0.43796 0.36562 0.37646 -0.02292 -0.08639 0.10753  22  GLU A CB  
181  C CG  A GLU A 22  ? 0.41690 0.35759 0.43633 0.02935  0.03355  0.07552  22  GLU A CG  
182  C CG  B GLU A 22  ? 0.43924 0.37547 0.36167 0.02429  -0.05194 0.11073  22  GLU A CG  
183  C CD  A GLU A 22  ? 0.39366 0.37252 0.45160 0.02148  0.02133  0.04237  22  GLU A CD  
184  C CD  B GLU A 22  ? 0.55285 0.47089 0.37459 -0.00294 -0.00815 0.11692  22  GLU A CD  
185  O OE1 A GLU A 22  ? 0.52949 0.42792 0.48634 0.06547  0.00269  0.02190  22  GLU A OE1 
186  O OE1 B GLU A 22  ? 0.50488 0.47462 0.37391 0.05769  -0.01504 0.08567  22  GLU A OE1 
187  O OE2 A GLU A 22  ? 0.43810 0.29626 0.45482 0.00178  0.00700  0.03384  22  GLU A OE2 
188  O OE2 B GLU A 22  ? 0.65052 0.43662 0.35863 0.03806  0.02637  0.14257  22  GLU A OE2 
189  N N   . ARG A 23  ? 0.45998 0.37726 0.37372 -0.02454 -0.04280 0.04545  23  ARG A N   
190  C CA  . ARG A 23  ? 0.43099 0.39582 0.38641 -0.02947 -0.00124 0.04688  23  ARG A CA  
191  C C   . ARG A 23  ? 0.39141 0.34801 0.42096 0.01545  -0.02102 0.03281  23  ARG A C   
192  O O   . ARG A 23  ? 0.39236 0.39584 0.43129 -0.00750 -0.00751 0.07252  23  ARG A O   
193  C CB  . ARG A 23  ? 0.46808 0.42842 0.34606 0.06200  0.05605  0.07117  23  ARG A CB  
194  C CG  . ARG A 23  ? 0.48686 0.38786 0.36796 0.04254  0.10758  0.08891  23  ARG A CG  
195  C CD  . ARG A 23  ? 0.45887 0.38826 0.36307 0.03547  0.06470  0.08179  23  ARG A CD  
196  N NE  . ARG A 23  ? 0.44690 0.37153 0.37353 0.00503  0.03251  0.06281  23  ARG A NE  
197  C CZ  . ARG A 23  ? 0.50855 0.46982 0.38036 -0.09340 0.06157  0.06760  23  ARG A CZ  
198  N NH1 . ARG A 23  ? 0.50208 0.48720 0.40904 -0.06048 0.07551  0.05371  23  ARG A NH1 
199  N NH2 . ARG A 23  ? 0.50115 0.54784 0.37563 -0.04474 -0.03444 0.02908  23  ARG A NH2 
200  N N   . TYR A 24  ? 0.41042 0.28751 0.40314 0.07059  0.04757  0.04212  24  TYR A N   
201  C CA  . TYR A 24  ? 0.37551 0.25944 0.41450 0.01136  0.08159  0.04675  24  TYR A CA  
202  C C   . TYR A 24  ? 0.34657 0.32081 0.45329 -0.06206 0.04099  0.01402  24  TYR A C   
203  O O   . TYR A 24  ? 0.47963 0.35908 0.45402 -0.04271 -0.01431 0.03231  24  TYR A O   
204  C CB  . TYR A 24  ? 0.42390 0.22728 0.40652 -0.03916 0.08324  0.07247  24  TYR A CB  
205  C CG  . TYR A 24  ? 0.43571 0.30067 0.40619 -0.06803 0.04581  0.04736  24  TYR A CG  
206  C CD1 . TYR A 24  ? 0.37275 0.31858 0.42029 0.02314  0.06002  0.06262  24  TYR A CD1 
207  C CD2 . TYR A 24  ? 0.41283 0.26274 0.40414 -0.08552 0.05507  0.05360  24  TYR A CD2 
208  C CE1 . TYR A 24  ? 0.37092 0.30456 0.38274 -0.00040 0.07857  0.07275  24  TYR A CE1 
209  C CE2 . TYR A 24  ? 0.41529 0.28288 0.40414 -0.05095 0.04699  0.06335  24  TYR A CE2 
210  C CZ  . TYR A 24  ? 0.43890 0.34027 0.36268 0.00171  0.07277  0.10788  24  TYR A CZ  
211  O OH  . TYR A 24  ? 0.37990 0.36528 0.37550 0.04722  0.00069  0.09778  24  TYR A OH  
212  N N   . GLN A 25  ? 0.35718 0.30849 0.49674 -0.09144 0.06036  0.05787  25  GLN A N   
213  C CA  . GLN A 25  ? 0.45479 0.36797 0.52807 -0.00614 0.06468  0.09299  25  GLN A CA  
214  C C   . GLN A 25  ? 0.43734 0.42501 0.58198 -0.08700 0.08906  0.06286  25  GLN A C   
215  O O   . GLN A 25  ? 0.39640 0.42367 0.60356 -0.01724 0.07276  -0.00779 25  GLN A O   
216  C CB  . GLN A 25  ? 0.42758 0.36543 0.45504 0.06817  -0.00424 0.09312  25  GLN A CB  
217  C CG  . GLN A 25  ? 0.41869 0.38167 0.44574 0.03553  -0.01626 0.07484  25  GLN A CG  
218  C CD  . GLN A 25  ? 0.52552 0.37771 0.43427 -0.03375 -0.03203 0.05277  25  GLN A CD  
219  O OE1 . GLN A 25  ? 0.59381 0.39883 0.45503 -0.08324 0.04625  0.06482  25  GLN A OE1 
220  N NE2 . GLN A 25  ? 0.52051 0.31422 0.43362 -0.09787 -0.02806 0.04371  25  GLN A NE2 
221  N N   . ASN A 26  ? 0.44744 0.44214 0.62443 -0.05359 0.18597  0.05409  26  ASN A N   
222  C CA  . ASN A 26  ? 0.50964 0.42381 0.66610 -0.09343 0.21086  0.06649  26  ASN A CA  
223  C C   . ASN A 26  ? 0.61358 0.47640 0.63237 -0.02938 0.20581  0.02726  26  ASN A C   
224  O O   . ASN A 26  ? 0.72350 0.49800 0.62791 -0.08657 0.20108  -0.02255 26  ASN A O   
225  C CB  . ASN A 26  ? 0.54252 0.52245 0.77130 -0.11424 0.20020  0.09876  26  ASN A CB  
226  C CG  . ASN A 26  ? 0.73940 0.66942 0.87178 -0.03178 0.19696  0.02176  26  ASN A CG  
227  O OD1 . ASN A 26  ? 0.84455 0.69015 0.90567 -0.00975 0.19039  -0.02751 26  ASN A OD1 
228  N ND2 . ASN A 26  ? 0.73014 0.64635 0.87216 -0.02750 0.23954  0.06838  26  ASN A ND2 
229  N N   . LEU A 27  ? 0.49554 0.44989 0.62054 -0.05807 0.18311  0.00678  27  LEU A N   
230  C CA  . LEU A 27  ? 0.44530 0.49238 0.61989 0.00855  0.12095  0.01246  27  LEU A CA  
231  C C   . LEU A 27  ? 0.45836 0.50169 0.61672 0.02548  0.12076  0.02506  27  LEU A C   
232  O O   . LEU A 27  ? 0.65105 0.57170 0.57275 -0.03733 0.11574  0.06302  27  LEU A O   
233  C CB  . LEU A 27  ? 0.36368 0.46323 0.64694 -0.02150 0.09348  -0.02697 27  LEU A CB  
234  C CG  . LEU A 27  ? 0.50068 0.46626 0.67350 -0.00595 0.07914  -0.05139 27  LEU A CG  
235  C CD1 . LEU A 27  ? 0.52734 0.48681 0.67206 -0.02906 0.03164  -0.06762 27  LEU A CD1 
236  C CD2 . LEU A 27  ? 0.50292 0.55428 0.66019 -0.00746 0.06467  -0.06085 27  LEU A CD2 
237  N N   A SER A 28  ? 0.52926 0.50180 0.63849 0.03257  0.11781  0.05186  28  SER A N   
238  N N   B SER A 28  ? 0.52649 0.48514 0.64869 0.02311  0.09148  0.04026  28  SER A N   
239  C CA  A SER A 28  ? 0.47854 0.53789 0.65013 0.03719  0.17853  0.08952  28  SER A CA  
240  C CA  B SER A 28  ? 0.48381 0.50889 0.67045 0.03191  0.12481  0.06740  28  SER A CA  
241  C C   A SER A 28  ? 0.49616 0.51726 0.67842 0.01323  0.17221  0.08355  28  SER A C   
242  C C   B SER A 28  ? 0.51039 0.50500 0.69098 0.02909  0.14628  0.06852  28  SER A C   
243  O O   A SER A 28  ? 0.50415 0.46219 0.67445 0.00920  0.11697  0.07597  28  SER A O   
244  O O   B SER A 28  ? 0.53056 0.43182 0.69133 0.07986  0.09714  0.05614  28  SER A O   
245  C CB  A SER A 28  ? 0.59688 0.62008 0.63071 0.02744  0.16424  0.09750  28  SER A CB  
246  C CB  B SER A 28  ? 0.55403 0.55992 0.66711 0.02542  0.06824  0.05201  28  SER A CB  
247  O OG  A SER A 28  ? 0.67563 0.68500 0.61566 -0.00880 0.16080  0.10568  28  SER A OG  
248  O OG  B SER A 28  ? 0.57252 0.59449 0.67889 0.03220  -0.01027 0.05695  28  SER A OG  
249  N N   . PRO A 29  ? 0.53376 0.56542 0.71500 0.06164  0.22581  0.08547  29  PRO A N   
250  C CA  . PRO A 29  ? 0.59793 0.57313 0.75696 0.19850  0.22281  0.07589  29  PRO A CA  
251  C C   . PRO A 29  ? 0.61132 0.65132 0.80399 0.18499  0.20397  0.07554  29  PRO A C   
252  O O   . PRO A 29  ? 0.55955 0.75464 0.81830 0.17701  0.20430  0.12640  29  PRO A O   
253  C CB  . PRO A 29  ? 0.69963 0.61363 0.75449 0.17701  0.29037  0.06314  29  PRO A CB  
254  C CG  . PRO A 29  ? 0.77815 0.62861 0.74894 0.18453  0.24141  0.06763  29  PRO A CG  
255  C CD  . PRO A 29  ? 0.69253 0.62937 0.72047 0.15603  0.21216  0.07632  29  PRO A CD  
256  N N   . VAL A 30  ? 0.55433 0.66342 0.83484 0.19305  0.18367  0.03614  30  VAL A N   
257  C CA  . VAL A 30  ? 0.61802 0.73751 0.87852 0.10430  0.10548  0.02782  30  VAL A CA  
258  C C   . VAL A 30  ? 0.70792 0.75598 0.92492 0.02643  0.06300  0.07033  30  VAL A C   
259  O O   . VAL A 30  ? 0.94820 0.78364 0.93337 -0.03635 0.07934  0.05534  30  VAL A O   
260  C CB  . VAL A 30  ? 0.63439 0.79552 0.87411 0.09735  0.09148  0.02388  30  VAL A CB  
261  C CG1 . VAL A 30  ? 0.65618 0.77815 0.86305 0.15224  0.02132  0.04775  30  VAL A CG1 
262  C CG2 . VAL A 30  ? 0.66848 0.81784 0.87855 0.02195  0.07451  0.01207  30  VAL A CG2 
263  N N   . GLY A 31  ? 0.59987 0.76672 0.97015 0.07666  0.02800  0.08067  31  GLY A N   
264  C CA  . GLY A 31  ? 0.68168 0.79649 1.03242 0.06808  0.01371  0.05384  31  GLY A CA  
265  C C   . GLY A 31  ? 0.66826 0.80766 1.07416 0.08139  0.01538  0.03497  31  GLY A C   
266  O O   . GLY A 31  ? 0.55364 0.77158 1.06940 0.07817  0.09571  0.03561  31  GLY A O   
267  N N   . SER A 32  ? 0.67424 0.85381 1.11312 0.15956  0.05758  0.01157  32  SER A N   
268  C CA  . SER A 32  ? 0.91025 0.93567 1.15970 0.12954  0.11122  0.01993  32  SER A CA  
269  C C   . SER A 32  ? 1.00256 0.97918 1.19419 0.06382  0.12480  0.03852  32  SER A C   
270  O O   . SER A 32  ? 1.07614 0.98497 1.19999 0.03250  0.12184  0.04929  32  SER A O   
271  C CB  . SER A 32  ? 1.10020 0.98621 1.17917 0.12244  0.12520  0.02217  32  SER A CB  
272  O OG  . SER A 32  ? 1.22866 1.02187 1.19474 0.10273  0.12899  0.00680  32  SER A OG  
273  N N   . GLY A 33  ? 1.00957 1.01821 1.22561 0.06532  0.15882  0.04325  33  GLY A N   
274  C CA  . GLY A 33  ? 1.04902 1.03603 1.25376 0.05129  0.16384  0.05832  33  GLY A CA  
275  C C   . GLY A 33  ? 1.12524 1.02963 1.28167 0.02144  0.19973  0.08375  33  GLY A C   
276  O O   . GLY A 33  ? 1.20115 1.04426 1.29743 0.00145  0.22054  0.05327  33  GLY A O   
277  N N   . ALA A 34  ? 1.12406 0.99301 1.29180 0.03110  0.16862  0.14323  34  ALA A N   
278  C CA  . ALA A 34  ? 1.14391 0.93817 1.30392 0.04150  0.14852  0.17543  34  ALA A CA  
279  C C   . ALA A 34  ? 1.16453 0.88518 1.30423 0.10120  0.08575  0.17166  34  ALA A C   
280  O O   . ALA A 34  ? 1.14340 0.82462 1.30694 0.18925  0.06584  0.20141  34  ALA A O   
281  C CB  . ALA A 34  ? 1.13574 0.95774 1.30945 0.00050  0.15961  0.19136  34  ALA A CB  
282  N N   . TYR A 35  ? 1.20734 0.87759 1.29452 0.06079  0.00234  0.13063  35  TYR A N   
283  C CA  . TYR A 35  ? 1.18151 0.85609 1.27843 0.03716  -0.05757 0.09746  35  TYR A CA  
284  C C   . TYR A 35  ? 0.99155 0.72000 1.21705 0.09428  -0.10124 0.10716  35  TYR A C   
285  O O   . TYR A 35  ? 0.81770 0.56523 1.20639 0.16963  -0.10714 0.10913  35  TYR A O   
286  C CB  . TYR A 35  ? 1.25280 0.96523 1.31472 0.00288  -0.05699 0.05893  35  TYR A CB  
287  C CG  . TYR A 35  ? 1.21323 1.07207 1.35135 -0.04538 -0.05679 0.00374  35  TYR A CG  
288  C CD1 . TYR A 35  ? 1.19360 1.10446 1.36601 -0.03344 -0.07622 -0.01346 35  TYR A CD1 
289  C CD2 . TYR A 35  ? 1.22006 1.11875 1.36819 -0.04912 -0.05208 -0.02047 35  TYR A CD2 
290  C CE1 . TYR A 35  ? 1.19927 1.13724 1.37366 -0.02346 -0.07358 -0.02172 35  TYR A CE1 
291  C CE2 . TYR A 35  ? 1.24567 1.12645 1.37648 -0.02759 -0.05325 -0.03007 35  TYR A CE2 
292  C CZ  . TYR A 35  ? 1.25898 1.14268 1.37907 -0.01800 -0.06249 -0.03848 35  TYR A CZ  
293  O OH  . TYR A 35  ? 1.35312 1.15432 1.38432 0.04467  -0.07656 -0.05887 35  TYR A OH  
294  N N   . GLY A 36  ? 0.90210 0.73886 1.15698 0.08404  -0.09525 0.12637  36  GLY A N   
295  C CA  . GLY A 36  ? 0.89744 0.77138 1.10029 0.08017  -0.06047 0.09961  36  GLY A CA  
296  C C   . GLY A 36  ? 0.83797 0.76688 1.03819 0.10831  -0.04157 0.08040  36  GLY A C   
297  O O   . GLY A 36  ? 0.89733 0.85360 1.09086 0.08720  -0.05153 0.08722  36  GLY A O   
298  N N   . SER A 37  ? 0.65556 0.63547 0.91247 0.19072  0.04782  0.08186  37  SER A N   
299  C CA  . SER A 37  ? 0.68035 0.56764 0.81703 0.18516  0.12064  0.03771  37  SER A CA  
300  C C   . SER A 37  ? 0.55791 0.51055 0.70005 0.13411  0.09989  0.02777  37  SER A C   
301  O O   . SER A 37  ? 0.49227 0.47220 0.59673 0.05137  0.04545  0.06533  37  SER A O   
302  C CB  . SER A 37  ? 0.81392 0.60450 0.81661 0.21786  0.19022  0.06722  37  SER A CB  
303  O OG  . SER A 37  ? 1.04016 0.72586 0.84428 0.11335  0.17740  0.09225  37  SER A OG  
304  N N   . VAL A 38  ? 0.51149 0.48220 0.67127 0.13832  0.08385  -0.00929 38  VAL A N   
305  C CA  . VAL A 38  ? 0.43139 0.43536 0.65181 0.11693  0.10783  0.04625  38  VAL A CA  
306  C C   . VAL A 38  ? 0.48259 0.46040 0.64444 0.08861  0.14999  0.05743  38  VAL A C   
307  O O   . VAL A 38  ? 0.47162 0.52101 0.67272 0.04890  0.19809  0.06493  38  VAL A O   
308  C CB  . VAL A 38  ? 0.45004 0.48230 0.66540 0.04748  0.12388  0.08355  38  VAL A CB  
309  C CG1 . VAL A 38  ? 0.49916 0.55408 0.69815 0.03615  0.10129  0.07700  38  VAL A CG1 
310  C CG2 . VAL A 38  ? 0.44929 0.53273 0.66166 0.02571  0.12925  0.14750  38  VAL A CG2 
311  N N   . CYS A 39  ? 0.55065 0.41410 0.60391 0.07738  0.08917  0.04619  39  CYS A N   
312  C CA  . CYS A 39  ? 0.48902 0.41183 0.60376 -0.03190 0.10467  -0.00014 39  CYS A CA  
313  C C   . CYS A 39  ? 0.48921 0.46015 0.58977 -0.01720 0.05229  0.00790  39  CYS A C   
314  O O   . CYS A 39  ? 0.47544 0.47953 0.56547 -0.04881 0.11159  0.03304  39  CYS A O   
315  C CB  . CYS A 39  ? 0.68673 0.41911 0.60667 -0.06524 0.13035  -0.01326 39  CYS A CB  
316  S SG  . CYS A 39  ? 0.70314 0.56070 0.66021 -0.05736 0.20743  -0.03620 39  CYS A SG  
317  N N   . ALA A 40  ? 0.44723 0.44211 0.60206 -0.01550 0.04454  0.01140  40  ALA A N   
318  C CA  . ALA A 40  ? 0.39538 0.45302 0.59887 -0.03331 0.06903  0.01640  40  ALA A CA  
319  C C   . ALA A 40  ? 0.38130 0.42860 0.56463 -0.01384 0.05612  0.02410  40  ALA A C   
320  O O   . ALA A 40  ? 0.51462 0.45036 0.54895 -0.00087 0.06840  0.00592  40  ALA A O   
321  C CB  . ALA A 40  ? 0.38644 0.47115 0.60089 -0.03205 0.08814  0.03004  40  ALA A CB  
322  N N   . ALA A 41  ? 0.34478 0.43078 0.55585 -0.01623 0.06889  0.02829  41  ALA A N   
323  C CA  . ALA A 41  ? 0.35803 0.35931 0.51695 -0.05285 -0.00191 0.00806  41  ALA A CA  
324  C C   . ALA A 41  ? 0.42879 0.39431 0.53815 -0.03246 0.01747  0.02667  41  ALA A C   
325  O O   . ALA A 41  ? 0.42612 0.42369 0.54526 -0.03698 0.03312  0.01532  41  ALA A O   
326  C CB  . ALA A 41  ? 0.31651 0.40355 0.50118 -0.07295 -0.02388 0.02304  41  ALA A CB  
327  N N   . PHE A 42  ? 0.32583 0.41856 0.54306 -0.03043 0.01635  0.01052  42  PHE A N   
328  C CA  . PHE A 42  ? 0.41779 0.38062 0.52908 -0.03149 0.01545  0.00154  42  PHE A CA  
329  C C   . PHE A 42  ? 0.40822 0.41211 0.47240 -0.06016 0.04154  0.00938  42  PHE A C   
330  O O   . PHE A 42  ? 0.47487 0.43034 0.47710 -0.01566 0.03420  0.00026  42  PHE A O   
331  C CB  . PHE A 42  ? 0.49702 0.42920 0.56535 -0.08649 0.00943  0.01242  42  PHE A CB  
332  C CG  . PHE A 42  ? 0.58497 0.45456 0.62576 -0.09784 0.04643  -0.00907 42  PHE A CG  
333  C CD1 . PHE A 42  ? 0.68556 0.47829 0.65868 -0.12220 0.06187  -0.02974 42  PHE A CD1 
334  C CD2 . PHE A 42  ? 0.58011 0.45969 0.65819 -0.02434 0.08221  -0.07883 42  PHE A CD2 
335  C CE1 . PHE A 42  ? 0.67171 0.49247 0.66447 -0.08730 0.05435  -0.05017 42  PHE A CE1 
336  C CE2 . PHE A 42  ? 0.61609 0.48288 0.68177 -0.07148 0.12387  -0.07480 42  PHE A CE2 
337  C CZ  . PHE A 42  ? 0.54836 0.50091 0.68565 -0.09468 0.08176  -0.03985 42  PHE A CZ  
338  N N   . ASP A 43  ? 0.40980 0.38227 0.40802 0.00748  0.03509  0.05032  43  ASP A N   
339  C CA  . ASP A 43  ? 0.30904 0.37695 0.41184 -0.03122 0.02242  0.06296  43  ASP A CA  
340  C C   . ASP A 43  ? 0.46816 0.33678 0.39772 0.01018  -0.05887 0.06337  43  ASP A C   
341  O O   . ASP A 43  ? 0.38729 0.39889 0.41677 0.01652  -0.02758 0.06321  43  ASP A O   
342  C CB  . ASP A 43  ? 0.37112 0.39950 0.40166 -0.07035 0.01541  0.07819  43  ASP A CB  
343  C CG  . ASP A 43  ? 0.42159 0.40991 0.41459 -0.02449 -0.06296 0.08781  43  ASP A CG  
344  O OD1 . ASP A 43  ? 0.43438 0.40405 0.46910 -0.01276 -0.06267 0.09870  43  ASP A OD1 
345  O OD2 . ASP A 43  ? 0.53804 0.36312 0.44209 -0.03557 -0.04655 0.04607  43  ASP A OD2 
346  N N   . THR A 44  ? 0.54962 0.27281 0.40636 -0.02678 -0.05230 0.06492  44  THR A N   
347  C CA  . THR A 44  ? 0.61733 0.34448 0.42321 0.02443  -0.02269 0.06379  44  THR A CA  
348  C C   . THR A 44  ? 0.52050 0.38779 0.44434 0.04905  -0.05561 0.09004  44  THR A C   
349  O O   . THR A 44  ? 0.53893 0.41683 0.42220 -0.00339 -0.06504 0.07702  44  THR A O   
350  C CB  . THR A 44  ? 0.64269 0.40844 0.39991 0.08303  -0.02866 0.04844  44  THR A CB  
351  O OG1 . THR A 44  ? 0.59905 0.38630 0.39595 0.04680  -0.05045 0.01610  44  THR A OG1 
352  C CG2 . THR A 44  ? 0.74830 0.42872 0.38904 0.10435  0.04316  0.00892  44  THR A CG2 
353  N N   . LYS A 45  ? 0.50048 0.35508 0.51284 0.00952  -0.02880 0.08111  45  LYS A N   
354  C CA  . LYS A 45  ? 0.54302 0.40602 0.60572 0.07927  -0.04910 0.05600  45  LYS A CA  
355  C C   . LYS A 45  ? 0.38599 0.39464 0.50389 0.09239  -0.02204 0.05870  45  LYS A C   
356  O O   . LYS A 45  ? 0.46715 0.41221 0.47938 0.03411  0.03773  0.05432  45  LYS A O   
357  C CB  . LYS A 45  ? 0.51151 0.46509 0.74189 -0.07234 0.05782  0.03465  45  LYS A CB  
358  C CG  . LYS A 45  ? 0.74158 0.57798 0.87816 -0.02597 -0.01382 -0.01349 45  LYS A CG  
359  C CD  . LYS A 45  ? 0.90283 0.65927 0.99678 0.00300  -0.03177 -0.02301 45  LYS A CD  
360  C CE  . LYS A 45  ? 1.01359 0.74267 1.05857 0.03116  -0.06224 -0.00333 45  LYS A CE  
361  N NZ  . LYS A 45  ? 1.01801 0.80118 1.09412 0.08704  -0.06459 -0.00621 45  LYS A NZ  
362  N N   . THR A 46  ? 0.37747 0.36213 0.49796 0.00273  -0.07225 0.02823  46  THR A N   
363  C CA  . THR A 46  ? 0.47820 0.40366 0.47557 -0.03112 -0.06184 0.01083  46  THR A CA  
364  C C   . THR A 46  ? 0.49437 0.41838 0.44092 -0.09548 -0.08625 -0.01684 46  THR A C   
365  O O   . THR A 46  ? 0.55990 0.41814 0.42787 -0.03624 -0.05127 -0.02398 46  THR A O   
366  C CB  . THR A 46  ? 0.48651 0.41970 0.47142 -0.00384 -0.03909 0.01943  46  THR A CB  
367  O OG1 . THR A 46  ? 0.44569 0.38921 0.46141 0.06540  0.00128  0.04479  46  THR A OG1 
368  C CG2 . THR A 46  ? 0.51219 0.43667 0.46667 0.01505  -0.00405 0.00783  46  THR A CG2 
369  N N   . GLY A 47  ? 0.48906 0.41689 0.48390 -0.00008 -0.08546 0.00119  47  GLY A N   
370  C CA  . GLY A 47  ? 0.51083 0.39833 0.48410 -0.02594 -0.12018 0.02100  47  GLY A CA  
371  C C   . GLY A 47  ? 0.46590 0.36237 0.52371 -0.02732 -0.10730 0.02899  47  GLY A C   
372  O O   . GLY A 47  ? 0.56947 0.42524 0.57401 -0.00825 -0.04165 -0.01822 47  GLY A O   
373  N N   . LEU A 48  ? 0.44967 0.29386 0.49972 -0.01622 -0.06064 0.03975  48  LEU A N   
374  C CA  . LEU A 48  ? 0.44697 0.37266 0.48502 -0.01059 -0.02927 0.05146  48  LEU A CA  
375  C C   . LEU A 48  ? 0.41908 0.46920 0.55012 -0.07045 -0.02910 0.03637  48  LEU A C   
376  O O   . LEU A 48  ? 0.40413 0.49438 0.54559 -0.03358 -0.09082 0.01132  48  LEU A O   
377  C CB  . LEU A 48  ? 0.53077 0.42034 0.44982 0.00609  -0.01594 0.02158  48  LEU A CB  
378  C CG  . LEU A 48  ? 0.60069 0.45804 0.45814 -0.03227 -0.02391 -0.01312 48  LEU A CG  
379  C CD1 . LEU A 48  ? 0.65757 0.42258 0.44427 0.02379  -0.04430 -0.03274 48  LEU A CD1 
380  C CD2 . LEU A 48  ? 0.52717 0.47283 0.44683 -0.06186 -0.08454 0.01285  48  LEU A CD2 
381  N N   . ARG A 49  ? 0.43206 0.47193 0.60943 -0.06838 -0.00425 0.04763  49  ARG A N   
382  C CA  . ARG A 49  ? 0.37542 0.52935 0.65937 -0.09960 -0.05554 0.05554  49  ARG A CA  
383  C C   . ARG A 49  ? 0.39137 0.50998 0.58506 0.00566  -0.05543 0.04790  49  ARG A C   
384  O O   . ARG A 49  ? 0.41314 0.53298 0.56189 -0.04585 -0.06373 -0.00756 49  ARG A O   
385  C CB  . ARG A 49  ? 0.40235 0.64267 0.74415 -0.11364 -0.10983 0.11623  49  ARG A CB  
386  C CG  . ARG A 49  ? 0.73508 0.77898 0.87284 -0.11006 -0.02540 0.15158  49  ARG A CG  
387  C CD  . ARG A 49  ? 1.06360 0.93100 1.01051 -0.13921 0.04274  0.16737  49  ARG A CD  
388  N NE  . ARG A 49  ? 1.27921 1.06157 1.11029 -0.12277 0.10627  0.19627  49  ARG A NE  
389  C CZ  . ARG A 49  ? 1.33520 1.14859 1.16724 -0.09037 0.13887  0.23522  49  ARG A CZ  
390  N NH1 . ARG A 49  ? 1.18140 1.16920 1.19245 -0.05513 0.13077  0.25064  49  ARG A NH1 
391  N NH2 . ARG A 49  ? 1.42968 1.15867 1.19361 -0.12559 0.15654  0.24756  49  ARG A NH2 
392  N N   . VAL A 50  ? 0.34630 0.44904 0.56172 0.02989  -0.01794 0.06542  50  VAL A N   
393  C CA  . VAL A 50  ? 0.33326 0.41899 0.51448 0.02770  0.02007  0.01944  50  VAL A CA  
394  C C   . VAL A 50  ? 0.34480 0.44430 0.54523 0.05362  -0.00005 0.03893  50  VAL A C   
395  O O   . VAL A 50  ? 0.39281 0.47074 0.54797 0.02413  0.00090  0.04226  50  VAL A O   
396  C CB  . VAL A 50  ? 0.31380 0.45288 0.42231 0.01986  0.01427  0.00769  50  VAL A CB  
397  C CG1 . VAL A 50  ? 0.37500 0.42463 0.36813 -0.01116 0.03851  0.00241  50  VAL A CG1 
398  C CG2 . VAL A 50  ? 0.43066 0.49872 0.40398 -0.06639 -0.00658 0.04000  50  VAL A CG2 
399  N N   . ALA A 51  ? 0.32547 0.36369 0.56188 -0.01269 -0.02843 0.06312  51  ALA A N   
400  C CA  . ALA A 51  ? 0.31594 0.40892 0.53483 0.05832  -0.03257 0.04841  51  ALA A CA  
401  C C   . ALA A 51  ? 0.30941 0.44456 0.50566 -0.05289 -0.00199 0.05380  51  ALA A C   
402  O O   . ALA A 51  ? 0.36263 0.42632 0.50036 -0.01896 0.05619  0.03295  51  ALA A O   
403  C CB  . ALA A 51  ? 0.32893 0.41898 0.50153 0.02747  0.00257  0.07349  51  ALA A CB  
404  N N   . VAL A 52  ? 0.33642 0.42055 0.50459 -0.01751 -0.01966 0.09160  52  VAL A N   
405  C CA  . VAL A 52  ? 0.35417 0.35376 0.48582 0.05842  -0.02434 0.07513  52  VAL A CA  
406  C C   . VAL A 52  ? 0.44766 0.34616 0.46946 0.05565  0.03600  0.07707  52  VAL A C   
407  O O   . VAL A 52  ? 0.48749 0.39643 0.44837 0.02506  0.01117  -0.03256 52  VAL A O   
408  C CB  . VAL A 52  ? 0.30642 0.37307 0.51313 -0.03988 0.00236  0.04806  52  VAL A CB  
409  C CG1 . VAL A 52  ? 0.38065 0.43540 0.48752 -0.02578 -0.05200 0.01444  52  VAL A CG1 
410  C CG2 . VAL A 52  ? 0.39722 0.40948 0.52588 0.08394  0.07496  0.13476  52  VAL A CG2 
411  N N   . LYS A 53  ? 0.42588 0.31622 0.45374 -0.00715 0.01412  0.10176  53  LYS A N   
412  C CA  . LYS A 53  ? 0.40539 0.31720 0.47486 -0.00134 -0.01368 0.09784  53  LYS A CA  
413  C C   . LYS A 53  ? 0.45553 0.39678 0.44864 -0.01490 0.02468  0.04148  53  LYS A C   
414  O O   . LYS A 53  ? 0.42259 0.41733 0.47856 0.00666  0.06219  0.00268  53  LYS A O   
415  C CB  . LYS A 53  ? 0.36983 0.35887 0.48414 0.03091  0.00027  0.12714  53  LYS A CB  
416  C CG  . LYS A 53  ? 0.44642 0.42755 0.50650 -0.01224 0.07232  0.11781  53  LYS A CG  
417  C CD  . LYS A 53  ? 0.53895 0.51615 0.51170 -0.01631 0.13181  0.16945  53  LYS A CD  
418  C CE  . LYS A 53  ? 0.58966 0.58620 0.52481 0.04135  0.06263  0.20895  53  LYS A CE  
419  N NZ  . LYS A 53  ? 0.70119 0.66100 0.52249 0.11475  -0.01857 0.21671  53  LYS A NZ  
420  N N   . LYS A 54  ? 0.48149 0.33444 0.40315 0.02507  0.01504  0.02874  54  LYS A N   
421  C CA  . LYS A 54  ? 0.47505 0.37518 0.40001 -0.02713 0.06527  0.01684  54  LYS A CA  
422  C C   . LYS A 54  ? 0.55064 0.32798 0.42338 0.00904  0.08703  0.07919  54  LYS A C   
423  O O   . LYS A 54  ? 0.55545 0.36974 0.47483 0.00511  0.09132  -0.00168 54  LYS A O   
424  C CB  . LYS A 54  ? 0.51063 0.43379 0.35702 -0.03598 0.07717  -0.01465 54  LYS A CB  
425  C CG  . LYS A 54  ? 0.60014 0.42679 0.39229 0.01961  0.08112  -0.01007 54  LYS A CG  
426  C CD  . LYS A 54  ? 0.56002 0.42597 0.41339 0.06409  0.04885  0.05012  54  LYS A CD  
427  C CE  . LYS A 54  ? 0.64227 0.39771 0.44803 0.03841  0.11387  -0.01352 54  LYS A CE  
428  N NZ  . LYS A 54  ? 0.71873 0.35596 0.46721 0.00689  0.09579  -0.02257 54  LYS A NZ  
429  N N   . LEU A 55  ? 0.52110 0.28146 0.43720 -0.00393 0.11717  0.05355  55  LEU A N   
430  C CA  . LEU A 55  ? 0.50946 0.28347 0.46407 0.04795  0.08837  0.02661  55  LEU A CA  
431  C C   . LEU A 55  ? 0.58352 0.36875 0.53724 0.04758  0.11639  0.07337  55  LEU A C   
432  O O   . LEU A 55  ? 0.61960 0.41549 0.53615 0.04642  0.03004  0.11824  55  LEU A O   
433  C CB  . LEU A 55  ? 0.50396 0.37006 0.44062 0.03543  0.16224  -0.03668 55  LEU A CB  
434  C CG  . LEU A 55  ? 0.50010 0.50512 0.46923 0.03027  0.16643  -0.00899 55  LEU A CG  
435  C CD1 . LEU A 55  ? 0.48915 0.57309 0.44458 0.01236  0.15813  0.05924  55  LEU A CD1 
436  C CD2 . LEU A 55  ? 0.62006 0.49845 0.50248 -0.02432 0.15538  -0.01770 55  LEU A CD2 
437  N N   . SER A 56  ? 0.59433 0.36506 0.61810 -0.01731 0.21894  0.05290  56  SER A N   
438  C CA  . SER A 56  ? 0.66255 0.50385 0.70717 -0.02880 0.33435  0.00324  56  SER A CA  
439  C C   . SER A 56  ? 0.83707 0.57786 0.72347 -0.00939 0.35482  -0.02094 56  SER A C   
440  O O   . SER A 56  ? 0.94274 0.56698 0.73567 -0.01734 0.33846  -0.02055 56  SER A O   
441  C CB  . SER A 56  ? 0.71519 0.57889 0.77384 0.08934  0.33455  -0.03547 56  SER A CB  
442  O OG  . SER A 56  ? 0.76603 0.68110 0.82894 0.08533  0.26116  -0.02623 56  SER A OG  
443  N N   . ARG A 57  ? 0.86953 0.64859 0.73231 -0.10001 0.37752  -0.07563 57  ARG A N   
444  C CA  . ARG A 57  ? 0.86260 0.74121 0.74965 -0.06891 0.32185  -0.07335 57  ARG A CA  
445  C C   . ARG A 57  ? 0.75363 0.64643 0.69217 -0.03035 0.29205  -0.07354 57  ARG A C   
446  O O   . ARG A 57  ? 0.75172 0.65821 0.70871 0.00372  0.33740  -0.13181 57  ARG A O   
447  C CB  . ARG A 57  ? 1.04698 0.93166 0.85055 -0.08536 0.18586  -0.04093 57  ARG A CB  
448  C CG  . ARG A 57  ? 1.17994 1.10118 0.95932 -0.10069 0.08715  -0.03141 57  ARG A CG  
449  C CD  . ARG A 57  ? 1.21736 1.23105 1.03819 -0.09507 -0.00593 -0.03846 57  ARG A CD  
450  N NE  . ARG A 57  ? 1.19351 1.31566 1.07899 -0.09246 -0.05878 -0.05138 57  ARG A NE  
451  C CZ  . ARG A 57  ? 1.12144 1.35848 1.09273 -0.10886 -0.04625 -0.07314 57  ARG A CZ  
452  N NH1 . ARG A 57  ? 1.14592 1.37105 1.07751 -0.09369 -0.08078 -0.07637 57  ARG A NH1 
453  N NH2 . ARG A 57  ? 1.00117 1.36893 1.10398 -0.12696 0.01585  -0.05968 57  ARG A NH2 
454  N N   . PRO A 58  ? 0.67785 0.50500 0.59564 -0.02370 0.17015  -0.08975 58  PRO A N   
455  C CA  . PRO A 58  ? 0.55854 0.47010 0.56741 -0.07876 0.10388  -0.05562 58  PRO A CA  
456  C C   . PRO A 58  ? 0.59304 0.46782 0.53051 -0.01813 0.12342  -0.03436 58  PRO A C   
457  O O   . PRO A 58  ? 0.46809 0.52108 0.53741 -0.02953 0.10304  0.01710  58  PRO A O   
458  C CB  . PRO A 58  ? 0.52137 0.47282 0.56301 -0.01979 0.10958  -0.05742 58  PRO A CB  
459  C CG  . PRO A 58  ? 0.66582 0.49282 0.57497 -0.03387 0.09323  -0.02314 58  PRO A CG  
460  C CD  . PRO A 58  ? 0.72953 0.52517 0.56777 -0.05579 0.10752  -0.06057 58  PRO A CD  
461  N N   . PHE A 59  ? 0.62255 0.45573 0.50472 -0.05499 0.15602  -0.09575 59  PHE A N   
462  C CA  . PHE A 59  ? 0.54332 0.44640 0.52600 -0.07364 0.18630  -0.14498 59  PHE A CA  
463  C C   . PHE A 59  ? 0.60635 0.55258 0.55528 -0.05984 0.12920  -0.14861 59  PHE A C   
464  O O   . PHE A 59  ? 0.60573 0.53502 0.55325 -0.10469 0.04736  -0.12488 59  PHE A O   
465  C CB  . PHE A 59  ? 0.47727 0.49300 0.51494 -0.04485 0.16853  -0.05552 59  PHE A CB  
466  C CG  . PHE A 59  ? 0.55765 0.48016 0.50955 -0.03021 0.10886  -0.06854 59  PHE A CG  
467  C CD1 . PHE A 59  ? 0.46934 0.49320 0.53770 -0.02167 0.13593  -0.06810 59  PHE A CD1 
468  C CD2 . PHE A 59  ? 0.60711 0.47316 0.51447 -0.05422 0.05248  -0.04616 59  PHE A CD2 
469  C CE1 . PHE A 59  ? 0.46305 0.49691 0.52827 -0.00868 0.10144  -0.04780 59  PHE A CE1 
470  C CE2 . PHE A 59  ? 0.51257 0.47099 0.49220 -0.07897 0.09757  -0.06153 59  PHE A CE2 
471  C CZ  . PHE A 59  ? 0.47007 0.47976 0.52044 -0.12071 0.06812  -0.04308 59  PHE A CZ  
472  N N   A GLN A 60  ? 0.56576 0.57129 0.58777 -0.05301 0.14546  -0.15069 60  GLN A N   
473  N N   B GLN A 60  ? 0.58316 0.56294 0.58423 -0.04514 0.15055  -0.14883 60  GLN A N   
474  C CA  A GLN A 60  ? 0.51420 0.56464 0.64732 -0.01994 0.19803  -0.14762 60  GLN A CA  
475  C CA  B GLN A 60  ? 0.56800 0.55398 0.62353 -0.02364 0.19372  -0.13866 60  GLN A CA  
476  C C   A GLN A 60  ? 0.63298 0.51280 0.64399 -0.04035 0.15697  -0.17232 60  GLN A C   
477  C C   B GLN A 60  ? 0.63395 0.52195 0.63511 -0.04735 0.18231  -0.14042 60  GLN A C   
478  O O   A GLN A 60  ? 0.61492 0.47443 0.65592 -0.06429 0.04698  -0.19065 60  GLN A O   
479  O O   B GLN A 60  ? 0.61086 0.51570 0.64371 -0.07385 0.15732  -0.12790 60  GLN A O   
480  C CB  A GLN A 60  ? 0.58359 0.68200 0.73105 -0.07518 0.15609  -0.08090 60  GLN A CB  
481  C CB  B GLN A 60  ? 0.60184 0.61232 0.65769 -0.04690 0.18995  -0.11293 60  GLN A CB  
482  C CG  A GLN A 60  ? 0.72665 0.77080 0.80716 -0.06558 0.12074  -0.04881 60  GLN A CG  
483  C CG  B GLN A 60  ? 0.66417 0.65163 0.68621 -0.05690 0.19299  -0.11804 60  GLN A CG  
484  C CD  A GLN A 60  ? 0.88820 0.82103 0.85049 -0.02105 0.08587  -0.08703 60  GLN A CD  
485  C CD  B GLN A 60  ? 0.80140 0.71221 0.71582 -0.08182 0.17115  -0.10204 60  GLN A CD  
486  O OE1 A GLN A 60  ? 0.89027 0.85020 0.87661 -0.03374 0.11632  -0.08831 60  GLN A OE1 
487  O OE1 B GLN A 60  ? 0.72663 0.72035 0.71802 -0.16437 0.20430  -0.08260 60  GLN A OE1 
488  N NE2 A GLN A 60  ? 0.93163 0.81312 0.84242 -0.00945 0.04507  -0.11131 60  GLN A NE2 
489  N NE2 B GLN A 60  ? 0.87825 0.74331 0.73031 -0.04686 0.17504  -0.10180 60  GLN A NE2 
490  N N   . SER A 61  ? 0.64568 0.49093 0.64418 -0.07065 0.21433  -0.12592 61  SER A N   
491  C CA  . SER A 61  ? 0.60868 0.52710 0.64309 -0.00989 0.21515  -0.10572 61  SER A CA  
492  C C   . SER A 61  ? 0.58110 0.49508 0.57698 -0.03406 0.17316  -0.08000 61  SER A C   
493  O O   . SER A 61  ? 0.55175 0.48046 0.53934 0.00488  0.12664  -0.09200 61  SER A O   
494  C CB  . SER A 61  ? 0.61451 0.57310 0.67058 0.04233  0.24184  -0.09943 61  SER A CB  
495  O OG  . SER A 61  ? 0.68325 0.59427 0.68377 0.02128  0.26667  -0.08327 61  SER A OG  
496  N N   . ILE A 62  ? 0.54741 0.47652 0.58721 -0.02024 0.17105  -0.04087 62  ILE A N   
497  C CA  . ILE A 62  ? 0.54656 0.46540 0.61494 -0.08090 0.12784  -0.00301 62  ILE A CA  
498  C C   . ILE A 62  ? 0.52307 0.45846 0.61786 -0.01411 0.15913  -0.02987 62  ILE A C   
499  O O   . ILE A 62  ? 0.58560 0.43387 0.60349 -0.02202 0.12722  -0.04168 62  ILE A O   
500  C CB  . ILE A 62  ? 0.69632 0.43449 0.62968 -0.08964 0.05140  0.05146  62  ILE A CB  
501  C CG1 . ILE A 62  ? 0.66627 0.43193 0.68118 -0.06542 0.01050  0.02613  62  ILE A CG1 
502  C CG2 . ILE A 62  ? 0.72298 0.40604 0.59987 -0.11749 0.07324  0.04926  62  ILE A CG2 
503  C CD1 . ILE A 62  ? 0.67292 0.45144 0.70515 -0.06254 -0.03057 -0.00250 62  ILE A CD1 
504  N N   . ILE A 63  ? 0.39343 0.43016 0.64522 0.02462  0.11468  -0.02299 63  ILE A N   
505  C CA  . ILE A 63  ? 0.53431 0.50060 0.66206 0.02835  0.12468  0.00303  63  ILE A CA  
506  C C   . ILE A 63  ? 0.64164 0.48096 0.64547 0.05245  0.09298  0.00253  63  ILE A C   
507  O O   . ILE A 63  ? 0.54096 0.46567 0.63560 -0.00084 0.03654  -0.00990 63  ILE A O   
508  C CB  . ILE A 63  ? 0.67787 0.61012 0.71036 0.04995  0.11674  -0.02126 63  ILE A CB  
509  C CG1 . ILE A 63  ? 0.76813 0.68508 0.75325 0.07068  0.05843  0.00900  63  ILE A CG1 
510  C CG2 . ILE A 63  ? 0.59500 0.66396 0.69763 0.07979  0.15196  -0.05052 63  ILE A CG2 
511  C CD1 . ILE A 63  ? 0.89229 0.74500 0.78288 -0.02114 0.04163  0.01523  63  ILE A CD1 
512  N N   . HIS A 64  ? 0.60220 0.48521 0.60091 0.11873  0.17295  0.00805  64  HIS A N   
513  C CA  . HIS A 64  ? 0.53971 0.47891 0.60839 0.06787  0.14455  -0.02049 64  HIS A CA  
514  C C   . HIS A 64  ? 0.54774 0.41049 0.53507 0.01768  0.15162  -0.01733 64  HIS A C   
515  O O   . HIS A 64  ? 0.49752 0.37461 0.51486 0.02782  0.09797  0.01113  64  HIS A O   
516  C CB  . HIS A 64  ? 0.68109 0.59388 0.66970 0.07062  0.19451  -0.00371 64  HIS A CB  
517  C CG  . HIS A 64  ? 0.85249 0.74644 0.77115 0.03990  0.15054  0.04664  64  HIS A CG  
518  N ND1 . HIS A 64  ? 0.94069 0.82333 0.81338 0.00373  0.15135  0.06133  64  HIS A ND1 
519  C CD2 . HIS A 64  ? 0.85405 0.79739 0.82037 0.01928  0.08171  0.03870  64  HIS A CD2 
520  C CE1 . HIS A 64  ? 0.86689 0.82354 0.83628 0.10333  0.15257  0.01142  64  HIS A CE1 
521  N NE2 . HIS A 64  ? 0.70807 0.82307 0.83713 0.09669  0.15600  0.01470  64  HIS A NE2 
522  N N   . ALA A 65  ? 0.49258 0.39421 0.54148 -0.04704 0.18279  -0.02339 65  ALA A N   
523  C CA  . ALA A 65  ? 0.48790 0.34500 0.47873 -0.03278 0.15290  -0.01694 65  ALA A CA  
524  C C   . ALA A 65  ? 0.44009 0.38588 0.46952 0.03793  0.11076  -0.01035 65  ALA A C   
525  O O   . ALA A 65  ? 0.48094 0.37383 0.45807 0.02784  0.11064  -0.00757 65  ALA A O   
526  C CB  . ALA A 65  ? 0.48915 0.39233 0.47979 -0.06439 0.13423  -0.07501 65  ALA A CB  
527  N N   . LYS A 66  ? 0.43900 0.35298 0.45780 -0.02513 0.06633  0.03001  66  LYS A N   
528  C CA  . LYS A 66  ? 0.44343 0.31846 0.42456 -0.00374 0.00454  0.02048  66  LYS A CA  
529  C C   . LYS A 66  ? 0.37732 0.30489 0.43515 -0.03274 0.05259  0.00086  66  LYS A C   
530  O O   . LYS A 66  ? 0.45463 0.38247 0.43187 -0.01672 0.04325  -0.03920 66  LYS A O   
531  C CB  . LYS A 66  ? 0.65972 0.29609 0.40023 0.05247  0.04659  0.03558  66  LYS A CB  
532  C CG  . LYS A 66  ? 0.60720 0.33514 0.39898 -0.01680 0.00822  0.07535  66  LYS A CG  
533  C CD  . LYS A 66  ? 0.61565 0.31046 0.38457 0.00933  0.01333  0.08553  66  LYS A CD  
534  C CE  . LYS A 66  ? 0.65570 0.34299 0.38687 -0.03177 0.08283  0.11153  66  LYS A CE  
535  N NZ  . LYS A 66  ? 0.78897 0.44245 0.42515 -0.00851 0.06059  0.07154  66  LYS A NZ  
536  N N   . ARG A 67  ? 0.33392 0.36957 0.47943 -0.04406 0.04743  -0.01903 67  ARG A N   
537  C CA  . ARG A 67  ? 0.38029 0.38557 0.46983 -0.05249 0.09830  0.01414  67  ARG A CA  
538  C C   . ARG A 67  ? 0.40773 0.34855 0.44765 0.01675  0.10878  0.04948  67  ARG A C   
539  O O   . ARG A 67  ? 0.42521 0.39782 0.41981 -0.06013 0.02865  -0.00910 67  ARG A O   
540  C CB  . ARG A 67  ? 0.37525 0.46595 0.53321 0.02120  0.08638  -0.03511 67  ARG A CB  
541  C CG  . ARG A 67  ? 0.59676 0.49944 0.56683 -0.01504 0.08989  -0.02467 67  ARG A CG  
542  C CD  . ARG A 67  ? 0.77634 0.53831 0.61364 -0.01923 0.05506  0.01846  67  ARG A CD  
543  N NE  . ARG A 67  ? 1.01474 0.63351 0.66864 0.01326  0.08515  -0.00999 67  ARG A NE  
544  C CZ  . ARG A 67  ? 1.08099 0.64028 0.68138 0.02918  0.09983  0.02849  67  ARG A CZ  
545  N NH1 . ARG A 67  ? 1.09176 0.62471 0.65886 -0.04478 0.10037  0.01207  67  ARG A NH1 
546  N NH2 . ARG A 67  ? 1.07107 0.63545 0.69673 0.08694  0.05060  0.05617  67  ARG A NH2 
547  N N   . THR A 68  ? 0.33659 0.31864 0.49286 0.05402  0.05654  0.04132  68  THR A N   
548  C CA  . THR A 68  ? 0.42778 0.35279 0.44759 0.10748  0.02149  0.01116  68  THR A CA  
549  C C   . THR A 68  ? 0.39769 0.35074 0.45454 0.01311  0.05014  -0.01656 68  THR A C   
550  O O   . THR A 68  ? 0.38155 0.30786 0.46234 0.01515  0.07925  0.00562  68  THR A O   
551  C CB  . THR A 68  ? 0.37012 0.39885 0.42919 0.04226  0.09842  0.04920  68  THR A CB  
552  O OG1 . THR A 68  ? 0.46439 0.38553 0.46038 0.06537  0.15171  0.02669  68  THR A OG1 
553  C CG2 . THR A 68  ? 0.42360 0.31395 0.41951 -0.03507 -0.02439 0.04331  68  THR A CG2 
554  N N   . TYR A 69  ? 0.36330 0.41545 0.43134 -0.01077 0.11518  -0.01544 69  TYR A N   
555  C CA  . TYR A 69  ? 0.28850 0.45175 0.40121 -0.02243 0.12161  -0.02222 69  TYR A CA  
556  C C   . TYR A 69  ? 0.40247 0.43313 0.38098 0.01621  0.09541  -0.02122 69  TYR A C   
557  O O   . TYR A 69  ? 0.30590 0.42457 0.34674 -0.00433 0.02773  0.02494  69  TYR A O   
558  C CB  . TYR A 69  ? 0.35299 0.39982 0.40583 -0.07438 0.09690  0.03727  69  TYR A CB  
559  C CG  . TYR A 69  ? 0.43207 0.37626 0.42195 -0.03070 0.10611  0.01670  69  TYR A CG  
560  C CD1 . TYR A 69  ? 0.30191 0.32626 0.41271 -0.05681 0.07473  0.06654  69  TYR A CD1 
561  C CD2 . TYR A 69  ? 0.39475 0.37454 0.38633 -0.00404 0.07261  0.00903  69  TYR A CD2 
562  C CE1 . TYR A 69  ? 0.33832 0.36533 0.41303 -0.06945 0.09788  0.08304  69  TYR A CE1 
563  C CE2 . TYR A 69  ? 0.43283 0.37313 0.40205 0.06465  0.07966  0.00569  69  TYR A CE2 
564  C CZ  . TYR A 69  ? 0.27072 0.36713 0.40184 -0.01493 0.12723  0.04978  69  TYR A CZ  
565  O OH  . TYR A 69  ? 0.37521 0.40544 0.44280 -0.06721 0.12565  0.02355  69  TYR A OH  
566  N N   . ARG A 70  ? 0.36203 0.37980 0.40847 0.06361  0.04125  0.02386  70  ARG A N   
567  C CA  . ARG A 70  ? 0.30207 0.31293 0.43961 -0.02206 0.00693  0.01548  70  ARG A CA  
568  C C   . ARG A 70  ? 0.34208 0.29052 0.41927 -0.03554 0.03730  0.02362  70  ARG A C   
569  O O   . ARG A 70  ? 0.32798 0.35733 0.38415 0.06344  0.03302  0.00944  70  ARG A O   
570  C CB  . ARG A 70  ? 0.34793 0.32602 0.48709 0.10773  0.04263  0.03348  70  ARG A CB  
571  C CG  . ARG A 70  ? 0.41810 0.29612 0.51445 0.00813  0.01310  0.06540  70  ARG A CG  
572  C CD  . ARG A 70  ? 0.41872 0.34381 0.52579 0.05127  0.02702  0.05973  70  ARG A CD  
573  N NE  . ARG A 70  ? 0.57679 0.37670 0.53612 0.10121  -0.02282 0.04802  70  ARG A NE  
574  C CZ  . ARG A 70  ? 0.78044 0.40999 0.53594 0.13558  -0.01757 0.01379  70  ARG A CZ  
575  N NH1 . ARG A 70  ? 0.91270 0.40346 0.50453 0.07924  0.03422  0.00686  70  ARG A NH1 
576  N NH2 . ARG A 70  ? 0.62041 0.41462 0.56244 0.11077  0.03851  0.00159  70  ARG A NH2 
577  N N   . GLU A 71  ? 0.37596 0.29992 0.43049 0.04566  0.08493  0.08457  71  GLU A N   
578  C CA  . GLU A 71  ? 0.33244 0.33758 0.43441 -0.03965 0.04742  0.11995  71  GLU A CA  
579  C C   . GLU A 71  ? 0.33093 0.41847 0.43721 0.03874  0.04122  0.07404  71  GLU A C   
580  O O   . GLU A 71  ? 0.31617 0.42492 0.40321 -0.02398 -0.00078 0.08249  71  GLU A O   
581  C CB  . GLU A 71  ? 0.34905 0.37901 0.45431 -0.11114 0.07911  0.09913  71  GLU A CB  
582  C CG  . GLU A 71  ? 0.38144 0.48900 0.44493 -0.05690 0.10925  0.07527  71  GLU A CG  
583  C CD  . GLU A 71  ? 0.64107 0.52721 0.49076 0.05804  0.09142  0.07881  71  GLU A CD  
584  O OE1 . GLU A 71  ? 0.66249 0.54799 0.49439 0.06932  0.10804  0.05395  71  GLU A OE1 
585  O OE2 . GLU A 71  ? 0.54582 0.54219 0.51747 0.10015  0.07574  0.06335  71  GLU A OE2 
586  N N   . LEU A 72  ? 0.28801 0.39180 0.44535 0.02806  0.04054  0.11411  72  LEU A N   
587  C CA  . LEU A 72  ? 0.30478 0.37904 0.41111 0.05968  0.04422  0.06962  72  LEU A CA  
588  C C   . LEU A 72  ? 0.32749 0.39554 0.37321 -0.00528 0.04044  0.05479  72  LEU A C   
589  O O   . LEU A 72  ? 0.35279 0.38136 0.37418 -0.03245 0.00975  0.01446  72  LEU A O   
590  C CB  . LEU A 72  ? 0.32559 0.33805 0.39764 0.02339  -0.02139 0.00722  72  LEU A CB  
591  C CG  . LEU A 72  ? 0.33946 0.37176 0.41525 0.01109  -0.00897 0.01381  72  LEU A CG  
592  C CD1 . LEU A 72  ? 0.42933 0.38373 0.44655 0.01500  0.01980  -0.01987 72  LEU A CD1 
593  C CD2 . LEU A 72  ? 0.39840 0.35308 0.39634 0.02082  -0.10297 0.02270  72  LEU A CD2 
594  N N   . ARG A 73  ? 0.28111 0.36595 0.34846 0.00686  0.04614  0.07188  73  ARG A N   
595  C CA  . ARG A 73  ? 0.32277 0.38780 0.32094 -0.01960 0.08306  0.02398  73  ARG A CA  
596  C C   . ARG A 73  ? 0.35378 0.34809 0.36540 -0.01465 0.05074  0.02346  73  ARG A C   
597  O O   . ARG A 73  ? 0.34550 0.32988 0.39093 0.01035  0.01006  -0.00873 73  ARG A O   
598  C CB  . ARG A 73  ? 0.28665 0.35546 0.36159 -0.07213 0.05716  0.02685  73  ARG A CB  
599  C CG  . ARG A 73  ? 0.29699 0.38410 0.37166 -0.03348 0.09948  0.04713  73  ARG A CG  
600  C CD  . ARG A 73  ? 0.33974 0.38350 0.35423 0.01780  0.08343  0.03751  73  ARG A CD  
601  N NE  . ARG A 73  ? 0.32233 0.44532 0.36540 -0.01432 0.10421  0.01012  73  ARG A NE  
602  C CZ  . ARG A 73  ? 0.39394 0.42993 0.34980 0.08033  0.15965  0.00891  73  ARG A CZ  
603  N NH1 . ARG A 73  ? 0.44201 0.45896 0.38053 0.04785  0.06574  0.02258  73  ARG A NH1 
604  N NH2 . ARG A 73  ? 0.41053 0.44760 0.35800 0.01484  0.13643  0.00043  73  ARG A NH2 
605  N N   A LEU A 74  ? 0.33916 0.32458 0.34619 -0.01621 0.01419  0.03192  74  LEU A N   
606  N N   B LEU A 74  ? 0.34810 0.36196 0.36580 -0.01519 0.02086  0.02059  74  LEU A N   
607  C CA  A LEU A 74  ? 0.32914 0.32677 0.34552 0.03535  0.00535  0.03927  74  LEU A CA  
608  C CA  B LEU A 74  ? 0.33786 0.40932 0.38923 0.05333  0.01502  0.02519  74  LEU A CA  
609  C C   A LEU A 74  ? 0.35860 0.33371 0.35786 0.01994  0.02492  0.04706  74  LEU A C   
610  C C   B LEU A 74  ? 0.39107 0.37210 0.37531 0.03767  0.01226  0.03464  74  LEU A C   
611  O O   A LEU A 74  ? 0.31980 0.31856 0.37935 -0.03238 0.04589  0.03587  74  LEU A O   
612  O O   B LEU A 74  ? 0.42696 0.33815 0.37725 0.03667  -0.00677 0.02713  74  LEU A O   
613  C CB  A LEU A 74  ? 0.41423 0.30478 0.33242 0.06270  -0.00157 0.06071  74  LEU A CB  
614  C CB  B LEU A 74  ? 0.44853 0.48409 0.42745 0.08145  0.03772  0.04150  74  LEU A CB  
615  C CG  A LEU A 74  ? 0.36713 0.31169 0.34330 0.04462  -0.03258 0.03288  74  LEU A CG  
616  C CG  B LEU A 74  ? 0.44714 0.58790 0.46757 0.10848  0.02272  0.02010  74  LEU A CG  
617  C CD1 A LEU A 74  ? 0.49750 0.34322 0.35031 0.04504  -0.01940 0.02247  74  LEU A CD1 
618  C CD1 B LEU A 74  ? 0.48357 0.63352 0.47286 0.09048  0.04141  0.02976  74  LEU A CD1 
619  C CD2 A LEU A 74  ? 0.46708 0.35413 0.36302 0.10517  0.01295  0.03627  74  LEU A CD2 
620  C CD2 B LEU A 74  ? 0.45284 0.59969 0.49102 0.02121  0.00057  -0.00122 74  LEU A CD2 
621  N N   A LEU A 75  ? 0.38472 0.33420 0.35138 -0.01352 0.06777  0.08093  75  LEU A N   
622  N N   B LEU A 75  ? 0.40168 0.35083 0.36034 -0.01106 0.07538  0.07475  75  LEU A N   
623  C CA  A LEU A 75  ? 0.37142 0.39654 0.34858 0.03538  0.05296  0.05489  75  LEU A CA  
624  C CA  B LEU A 75  ? 0.35497 0.41004 0.34749 0.04300  0.06432  0.02969  75  LEU A CA  
625  C C   A LEU A 75  ? 0.35590 0.38803 0.34053 0.03090  0.03242  0.04796  75  LEU A C   
626  C C   B LEU A 75  ? 0.36106 0.39737 0.33839 0.04346  0.03742  0.02451  75  LEU A C   
627  O O   A LEU A 75  ? 0.33225 0.37754 0.35113 -0.00200 -0.00784 0.04195  75  LEU A O   
628  O O   B LEU A 75  ? 0.34708 0.40004 0.34390 0.01423  -0.00115 -0.01140 75  LEU A O   
629  C CB  A LEU A 75  ? 0.34189 0.41879 0.35215 0.06409  0.06124  0.05285  75  LEU A CB  
630  C CB  B LEU A 75  ? 0.25583 0.41622 0.34577 0.08879  0.05923  -0.01252 75  LEU A CB  
631  C CG  A LEU A 75  ? 0.44179 0.44923 0.35682 0.04202  0.01770  0.06199  75  LEU A CG  
632  C CG  B LEU A 75  ? 0.24077 0.43601 0.35654 0.04094  -0.02094 -0.02237 75  LEU A CG  
633  C CD1 A LEU A 75  ? 0.50094 0.46317 0.37472 -0.04898 0.05918  0.09786  75  LEU A CD1 
634  C CD1 B LEU A 75  ? 0.32054 0.43760 0.35987 0.03901  0.02690  -0.05352 75  LEU A CD1 
635  C CD2 A LEU A 75  ? 0.43561 0.46282 0.36221 0.02532  0.01585  0.04039  75  LEU A CD2 
636  C CD2 B LEU A 75  ? 0.16704 0.48216 0.39550 -0.07381 -0.00204 -0.03558 75  LEU A CD2 
637  N N   . LYS A 76  ? 0.28254 0.39612 0.32378 -0.00754 0.04357  0.07210  76  LYS A N   
638  C CA  . LYS A 76  ? 0.19858 0.36415 0.30097 -0.02704 -0.01318 0.04492  76  LYS A CA  
639  C C   . LYS A 76  ? 0.41184 0.35121 0.35365 0.01536  0.04213  0.02641  76  LYS A C   
640  O O   . LYS A 76  ? 0.44140 0.37895 0.34836 0.01698  -0.00141 -0.04401 76  LYS A O   
641  C CB  . LYS A 76  ? 0.23018 0.35393 0.33594 0.01027  -0.03145 0.07520  76  LYS A CB  
642  C CG  . LYS A 76  ? 0.28116 0.35912 0.37334 -0.05517 0.00140  0.05405  76  LYS A CG  
643  C CD  . LYS A 76  ? 0.31646 0.34190 0.39395 0.01121  0.00244  0.00537  76  LYS A CD  
644  C CE  . LYS A 76  ? 0.33381 0.38287 0.35611 0.01062  -0.06645 0.01224  76  LYS A CE  
645  N NZ  . LYS A 76  ? 0.33303 0.41127 0.34605 -0.02920 -0.04188 0.01013  76  LYS A NZ  
646  N N   . HIS A 77  ? 0.40488 0.30757 0.32412 0.02009  0.04841  0.04665  77  HIS A N   
647  C CA  . HIS A 77  ? 0.43712 0.33231 0.31989 0.06830  -0.00168 0.07921  77  HIS A CA  
648  C C   . HIS A 77  ? 0.31511 0.36201 0.35470 0.03146  0.01955  0.01092  77  HIS A C   
649  O O   . HIS A 77  ? 0.33177 0.39193 0.37448 0.02932  -0.01341 -0.00488 77  HIS A O   
650  C CB  . HIS A 77  ? 0.42268 0.33902 0.33510 0.02670  0.03761  0.03002  77  HIS A CB  
651  C CG  . HIS A 77  ? 0.53095 0.39337 0.36807 -0.03396 0.07824  -0.02031 77  HIS A CG  
652  N ND1 . HIS A 77  ? 0.48630 0.48057 0.43792 -0.07756 0.11752  -0.05367 77  HIS A ND1 
653  C CD2 . HIS A 77  ? 0.56327 0.37021 0.41643 0.03699  0.06550  0.03547  77  HIS A CD2 
654  C CE1 . HIS A 77  ? 0.52347 0.49284 0.44237 -0.05422 0.10220  -0.07447 77  HIS A CE1 
655  N NE2 . HIS A 77  ? 0.60960 0.41420 0.44222 0.00008  0.06398  -0.01285 77  HIS A NE2 
656  N N   . MET A 78  ? 0.24098 0.44192 0.39270 0.02886  0.02742  0.07075  78  MET A N   
657  C CA  . MET A 78  ? 0.29743 0.42965 0.42061 0.10290  0.00055  0.02713  78  MET A CA  
658  C C   . MET A 78  ? 0.40802 0.43258 0.40024 0.04286  -0.02071 0.07208  78  MET A C   
659  O O   . MET A 78  ? 0.44340 0.47247 0.42507 -0.01253 -0.05698 0.11950  78  MET A O   
660  C CB  . MET A 78  ? 0.32427 0.52246 0.43116 0.08370  -0.02596 0.00245  78  MET A CB  
661  C CG  . MET A 78  ? 0.45210 0.54899 0.47731 0.04519  -0.05222 -0.02949 78  MET A CG  
662  S SD  . MET A 78  ? 0.50306 0.47273 0.52831 0.03310  -0.00164 -0.05156 78  MET A SD  
663  C CE  . MET A 78  ? 0.59697 0.55896 0.59098 0.01535  -0.02416 -0.09821 78  MET A CE  
664  N N   . LYS A 79  ? 0.39432 0.43569 0.40568 0.02502  0.04282  0.06784  79  LYS A N   
665  C CA  . LYS A 79  ? 0.25491 0.41474 0.42066 0.02885  -0.01938 0.07948  79  LYS A CA  
666  C C   . LYS A 79  ? 0.37420 0.41736 0.43106 -0.01059 0.01105  0.04831  79  LYS A C   
667  O O   . LYS A 79  ? 0.32740 0.43354 0.42949 -0.00142 0.02430  0.03363  79  LYS A O   
668  C CB  . LYS A 79  ? 0.33524 0.44201 0.44497 0.13476  -0.01193 0.10533  79  LYS A CB  
669  C CG  . LYS A 79  ? 0.62633 0.57581 0.43883 0.04027  -0.02360 0.07047  79  LYS A CG  
670  C CD  . LYS A 79  ? 0.85389 0.64327 0.48387 0.08438  -0.05038 0.02096  79  LYS A CD  
671  C CE  . LYS A 79  ? 0.93441 0.66386 0.54324 0.23706  -0.10012 0.03067  79  LYS A CE  
672  N NZ  . LYS A 79  ? 1.01576 0.68547 0.60007 0.29061  -0.09458 -0.02349 79  LYS A NZ  
673  N N   . HIS A 80  ? 0.36881 0.37988 0.44716 0.01557  -0.04910 0.00174  80  HIS A N   
674  C CA  . HIS A 80  ? 0.27178 0.38764 0.44081 0.01961  -0.04199 0.06369  80  HIS A CA  
675  C C   . HIS A 80  ? 0.28246 0.37446 0.43551 -0.09723 -0.05618 0.03624  80  HIS A C   
676  O O   . HIS A 80  ? 0.36563 0.45483 0.41857 0.02027  -0.04076 0.04344  80  HIS A O   
677  C CB  . HIS A 80  ? 0.36991 0.35907 0.39002 -0.01308 -0.01852 0.09567  80  HIS A CB  
678  C CG  . HIS A 80  ? 0.47211 0.38264 0.40797 0.01138  -0.01103 0.02882  80  HIS A CG  
679  N ND1 . HIS A 80  ? 0.33613 0.34974 0.39076 0.01177  0.03917  -0.02706 80  HIS A ND1 
680  C CD2 . HIS A 80  ? 0.49237 0.33850 0.41522 0.04601  -0.04509 0.00641  80  HIS A CD2 
681  C CE1 . HIS A 80  ? 0.40061 0.36562 0.37777 0.05878  0.02495  -0.03222 80  HIS A CE1 
682  N NE2 . HIS A 80  ? 0.45276 0.30315 0.40838 0.05073  -0.11483 0.01676  80  HIS A NE2 
683  N N   . GLU A 81  ? 0.27899 0.30258 0.45606 -0.10647 -0.06709 -0.01676 81  GLU A N   
684  C CA  . GLU A 81  ? 0.28267 0.34276 0.49471 -0.04432 -0.02898 0.04176  81  GLU A CA  
685  C C   . GLU A 81  ? 0.31698 0.34465 0.47986 0.03505  -0.02795 0.06634  81  GLU A C   
686  O O   . GLU A 81  ? 0.35502 0.33596 0.50975 -0.03523 0.01983  0.06025  81  GLU A O   
687  C CB  . GLU A 81  ? 0.41604 0.39381 0.56010 0.06442  -0.04413 0.04418  81  GLU A CB  
688  C CG  . GLU A 81  ? 0.48796 0.49111 0.68781 0.14104  -0.05506 0.07717  81  GLU A CG  
689  C CD  . GLU A 81  ? 0.80125 0.61764 0.83606 0.15891  -0.04512 0.10710  81  GLU A CD  
690  O OE1 . GLU A 81  ? 0.78913 0.61276 0.88091 0.16938  -0.10446 0.10619  81  GLU A OE1 
691  O OE2 . GLU A 81  ? 0.84329 0.64167 0.86724 0.19027  -0.05515 0.14258  81  GLU A OE2 
692  N N   . ASN A 82  ? 0.31518 0.27291 0.46083 0.08950  -0.06089 0.05157  82  ASN A N   
693  C CA  . ASN A 82  ? 0.29764 0.29788 0.41679 0.07031  -0.06042 0.02582  82  ASN A CA  
694  C C   . ASN A 82  ? 0.34482 0.31733 0.39521 0.00354  -0.02443 -0.01237 82  ASN A C   
695  O O   . ASN A 82  ? 0.31642 0.38236 0.40175 -0.01095 -0.00049 0.03026  82  ASN A O   
696  C CB  . ASN A 82  ? 0.41379 0.35582 0.40329 0.00729  -0.04207 0.04309  82  ASN A CB  
697  C CG  . ASN A 82  ? 0.33812 0.43901 0.39533 -0.03000 0.07608  0.04747  82  ASN A CG  
698  O OD1 . ASN A 82  ? 0.36110 0.40139 0.37888 0.00285  0.01635  0.00286  82  ASN A OD1 
699  N ND2 . ASN A 82  ? 0.25736 0.41166 0.47257 0.00245  0.00856  0.05222  82  ASN A ND2 
700  N N   . VAL A 83  ? 0.32764 0.31893 0.37854 0.00492  -0.01966 0.01579  83  VAL A N   
701  C CA  . VAL A 83  ? 0.32763 0.35795 0.34733 -0.04791 -0.03102 -0.02998 83  VAL A CA  
702  C C   . VAL A 83  ? 0.33732 0.43271 0.37334 -0.01718 -0.01258 -0.02305 83  VAL A C   
703  O O   . VAL A 83  ? 0.32562 0.43021 0.36467 0.03798  -0.02519 0.00853  83  VAL A O   
704  C CB  . VAL A 83  ? 0.35958 0.41524 0.33045 -0.07319 -0.03842 -0.02207 83  VAL A CB  
705  C CG1 . VAL A 83  ? 0.32421 0.43115 0.34796 -0.01420 -0.08536 -0.03577 83  VAL A CG1 
706  C CG2 . VAL A 83  ? 0.29133 0.41849 0.33930 0.02827  0.00768  0.00853  83  VAL A CG2 
707  N N   . ILE A 84  ? 0.31893 0.45236 0.39675 -0.03024 -0.07286 -0.00247 84  ILE A N   
708  C CA  . ILE A 84  ? 0.40534 0.57813 0.42208 0.03409  -0.13530 -0.01434 84  ILE A CA  
709  C C   . ILE A 84  ? 0.41538 0.63669 0.41587 -0.02445 -0.04339 0.02402  84  ILE A C   
710  O O   . ILE A 84  ? 0.33934 0.68015 0.49195 -0.01262 -0.07707 0.07823  84  ILE A O   
711  C CB  . ILE A 84  ? 0.53884 0.62295 0.46464 0.07372  -0.03796 0.02003  84  ILE A CB  
712  C CG1 . ILE A 84  ? 0.44735 0.67873 0.47244 0.12192  -0.00564 0.10665  84  ILE A CG1 
713  C CG2 . ILE A 84  ? 0.60279 0.67865 0.49456 0.09791  -0.08896 -0.01508 84  ILE A CG2 
714  C CD1 . ILE A 84  ? 0.67207 0.68988 0.51524 0.08885  -0.00394 0.16255  84  ILE A CD1 
715  N N   . GLY A 85  ? 0.37180 0.64778 0.38123 0.07280  -0.03411 -0.01938 85  GLY A N   
716  C CA  . GLY A 85  ? 0.38360 0.65472 0.39265 0.06518  0.01080  0.00993  85  GLY A CA  
717  C C   . GLY A 85  ? 0.34627 0.54395 0.39716 0.09928  -0.05396 0.01818  85  GLY A C   
718  O O   . GLY A 85  ? 0.47082 0.64722 0.40540 0.11110  -0.03101 -0.01145 85  GLY A O   
719  N N   A LEU A 86  ? 0.33909 0.48768 0.40574 0.12005  -0.03518 0.00758  86  LEU A N   
720  N N   B LEU A 86  ? 0.29397 0.46989 0.39546 0.13763  -0.02510 0.02138  86  LEU A N   
721  C CA  A LEU A 86  ? 0.35367 0.41846 0.40190 0.05338  -0.02032 0.01844  86  LEU A CA  
722  C CA  B LEU A 86  ? 0.35132 0.38676 0.35466 0.03435  0.00350  0.03593  86  LEU A CA  
723  C C   A LEU A 86  ? 0.34513 0.40318 0.38605 0.05646  -0.01113 0.04028  86  LEU A C   
724  C C   B LEU A 86  ? 0.32527 0.37792 0.34685 0.08073  0.05905  0.05379  86  LEU A C   
725  O O   A LEU A 86  ? 0.34877 0.41379 0.37522 0.04621  -0.02861 0.04307  86  LEU A O   
726  O O   B LEU A 86  ? 0.44746 0.34153 0.32701 0.07440  0.03244  0.02323  86  LEU A O   
727  C CB  A LEU A 86  ? 0.33006 0.39206 0.42574 0.05110  0.02022  0.01287  86  LEU A CB  
728  C CB  B LEU A 86  ? 0.35934 0.34844 0.33804 0.00853  0.01870  0.04539  86  LEU A CB  
729  C CG  A LEU A 86  ? 0.38524 0.37494 0.45011 0.07373  0.01476  0.00682  86  LEU A CG  
730  C CG  B LEU A 86  ? 0.35122 0.32724 0.33919 0.05949  -0.01386 0.05553  86  LEU A CG  
731  C CD1 A LEU A 86  ? 0.33398 0.32480 0.46594 0.02643  0.02965  0.01009  86  LEU A CD1 
732  C CD1 B LEU A 86  ? 0.38948 0.35093 0.35225 0.10322  0.06446  0.07888  86  LEU A CD1 
733  C CD2 A LEU A 86  ? 0.40539 0.37592 0.44867 0.06356  0.04884  0.00685  86  LEU A CD2 
734  C CD2 B LEU A 86  ? 0.47963 0.34922 0.37543 0.04916  -0.01229 0.07088  86  LEU A CD2 
735  N N   . LEU A 87  ? 0.37939 0.38382 0.37584 0.00639  -0.02353 0.05400  87  LEU A N   
736  C CA  . LEU A 87  ? 0.31953 0.37991 0.42110 0.01539  -0.04127 0.03840  87  LEU A CA  
737  C C   . LEU A 87  ? 0.34811 0.35461 0.39748 0.03643  -0.01784 0.02581  87  LEU A C   
738  O O   . LEU A 87  ? 0.36725 0.34330 0.40566 0.04707  -0.01587 -0.01834 87  LEU A O   
739  C CB  . LEU A 87  ? 0.29198 0.40824 0.44674 -0.04056 -0.01257 0.03415  87  LEU A CB  
740  C CG  . LEU A 87  ? 0.32464 0.46536 0.43847 -0.01793 -0.00882 -0.00215 87  LEU A CG  
741  C CD1 . LEU A 87  ? 0.37447 0.49770 0.44171 -0.00608 0.02470  0.09111  87  LEU A CD1 
742  C CD2 . LEU A 87  ? 0.50725 0.46771 0.42604 -0.08431 0.02533  -0.04363 87  LEU A CD2 
743  N N   . ASP A 88  ? 0.38668 0.34985 0.32053 0.00833  -0.03003 0.03503  88  ASP A N   
744  C CA  . ASP A 88  ? 0.40773 0.33043 0.30543 0.00521  -0.04528 0.10268  88  ASP A CA  
745  C C   . ASP A 88  ? 0.35956 0.32204 0.34463 0.00355  -0.03409 0.05207  88  ASP A C   
746  O O   . ASP A 88  ? 0.33876 0.30102 0.39534 0.01341  -0.00835 0.05111  88  ASP A O   
747  C CB  . ASP A 88  ? 0.50622 0.32495 0.31328 0.04887  -0.02165 0.10284  88  ASP A CB  
748  C CG  . ASP A 88  ? 0.53852 0.41087 0.34469 0.01887  0.03233  0.09834  88  ASP A CG  
749  O OD1 . ASP A 88  ? 0.44896 0.46276 0.35033 0.04384  0.01847  0.08055  88  ASP A OD1 
750  O OD2 . ASP A 88  ? 0.34334 0.48276 0.36638 0.02071  -0.00781 0.07631  88  ASP A OD2 
751  N N   . VAL A 89  ? 0.32536 0.34189 0.34921 -0.05121 -0.04330 0.02201  89  VAL A N   
752  C CA  . VAL A 89  ? 0.37224 0.37779 0.35418 -0.02883 -0.00744 0.02790  89  VAL A CA  
753  C C   . VAL A 89  ? 0.41656 0.41401 0.36781 -0.01545 -0.01974 0.05534  89  VAL A C   
754  O O   . VAL A 89  ? 0.40636 0.49080 0.39938 -0.00527 -0.01501 0.06074  89  VAL A O   
755  C CB  . VAL A 89  ? 0.42684 0.34606 0.33731 -0.04332 0.08984  0.03481  89  VAL A CB  
756  C CG1 . VAL A 89  ? 0.44919 0.39560 0.30139 -0.02168 0.04315  0.05870  89  VAL A CG1 
757  C CG2 . VAL A 89  ? 0.47317 0.30221 0.34580 0.00884  0.00286  0.04806  89  VAL A CG2 
758  N N   . PHE A 90  ? 0.40070 0.37285 0.34687 0.00472  -0.01048 0.05830  90  PHE A N   
759  C CA  . PHE A 90  ? 0.43316 0.38650 0.32873 -0.03126 -0.05996 0.06041  90  PHE A CA  
760  C C   . PHE A 90  ? 0.41754 0.33071 0.35288 0.01358  -0.02778 0.04398  90  PHE A C   
761  O O   . PHE A 90  ? 0.38908 0.31697 0.38932 0.01136  -0.02828 0.01941  90  PHE A O   
762  C CB  . PHE A 90  ? 0.49095 0.34363 0.33248 -0.04168 -0.00499 0.08971  90  PHE A CB  
763  C CG  . PHE A 90  ? 0.56126 0.41245 0.34664 -0.06872 0.02656  0.11248  90  PHE A CG  
764  C CD1 . PHE A 90  ? 0.52975 0.37874 0.32119 -0.02597 0.04910  0.16883  90  PHE A CD1 
765  C CD2 . PHE A 90  ? 0.59854 0.43000 0.32958 -0.06277 0.01680  0.12658  90  PHE A CD2 
766  C CE1 . PHE A 90  ? 0.49567 0.35925 0.38605 -0.04726 -0.02260 0.12566  90  PHE A CE1 
767  C CE2 . PHE A 90  ? 0.48419 0.40979 0.33349 -0.01980 0.01280  0.12196  90  PHE A CE2 
768  C CZ  . PHE A 90  ? 0.49104 0.42140 0.35285 0.01892  -0.01531 0.16683  90  PHE A CZ  
769  N N   . THR A 91  ? 0.38522 0.36601 0.37408 -0.04383 -0.03499 0.06093  91  THR A N   
770  C CA  . THR A 91  ? 0.49881 0.39450 0.36996 -0.00529 -0.03350 0.03803  91  THR A CA  
771  C C   . THR A 91  ? 0.48051 0.42025 0.38607 -0.00427 -0.01022 0.04413  91  THR A C   
772  O O   . THR A 91  ? 0.54338 0.37419 0.38548 -0.06345 -0.02932 0.03324  91  THR A O   
773  C CB  . THR A 91  ? 0.55022 0.39898 0.36450 -0.06303 -0.01710 0.04229  91  THR A CB  
774  O OG1 . THR A 91  ? 0.56852 0.46158 0.40648 -0.10790 -0.04013 -0.00918 91  THR A OG1 
775  C CG2 . THR A 91  ? 0.42253 0.37259 0.36855 -0.03341 0.03243  0.06459  91  THR A CG2 
776  N N   . PRO A 92  ? 0.52581 0.44132 0.42251 -0.05707 -0.06639 0.02114  92  PRO A N   
777  C CA  . PRO A 92  ? 0.58452 0.46727 0.42896 -0.09889 -0.06819 0.04257  92  PRO A CA  
778  C C   . PRO A 92  ? 0.56595 0.43533 0.45606 -0.09996 -0.08520 0.04122  92  PRO A C   
779  O O   . PRO A 92  ? 0.60534 0.46811 0.47694 -0.09281 -0.09486 0.07533  92  PRO A O   
780  C CB  . PRO A 92  ? 0.66182 0.45689 0.38323 -0.11656 0.01955  0.07204  92  PRO A CB  
781  C CG  . PRO A 92  ? 0.73288 0.42708 0.39925 0.00311  -0.02987 0.03174  92  PRO A CG  
782  C CD  . PRO A 92  ? 0.66770 0.42911 0.42394 -0.03179 -0.05365 0.03439  92  PRO A CD  
783  N N   . ALA A 93  ? 0.54373 0.39819 0.44456 -0.13365 -0.01183 0.05075  93  ALA A N   
784  C CA  . ALA A 93  ? 0.51809 0.44261 0.48820 -0.13372 -0.03526 0.09729  93  ALA A CA  
785  C C   . ALA A 93  ? 0.50312 0.55418 0.50112 -0.08899 -0.09045 0.10300  93  ALA A C   
786  O O   . ALA A 93  ? 0.55997 0.58560 0.48383 -0.04776 -0.07440 0.13775  93  ALA A O   
787  C CB  . ALA A 93  ? 0.58347 0.43116 0.48349 -0.08577 -0.06192 0.11446  93  ALA A CB  
788  N N   . ARG A 94  ? 0.53039 0.63112 0.51332 -0.06629 -0.08635 0.09667  94  ARG A N   
789  C CA  . ARG A 94  ? 0.50314 0.65464 0.58287 -0.12261 -0.10059 0.16128  94  ARG A CA  
790  C C   . ARG A 94  ? 0.48209 0.62931 0.62204 -0.04485 -0.07634 0.13826  94  ARG A C   
791  O O   . ARG A 94  ? 0.44891 0.64171 0.70770 -0.00021 -0.11517 0.11916  94  ARG A O   
792  C CB  . ARG A 94  ? 0.58150 0.73193 0.62890 -0.11852 -0.17193 0.25999  94  ARG A CB  
793  C CG  . ARG A 94  ? 0.63561 0.80714 0.68941 -0.17045 -0.16731 0.28477  94  ARG A CG  
794  C CD  . ARG A 94  ? 0.75020 0.92924 0.76675 -0.12595 -0.14769 0.24470  94  ARG A CD  
795  N NE  . ARG A 94  ? 0.89116 1.05305 0.83141 -0.02369 -0.16191 0.22211  94  ARG A NE  
796  C CZ  . ARG A 94  ? 0.93697 1.12702 0.87234 -0.01420 -0.11793 0.18562  94  ARG A CZ  
797  N NH1 . ARG A 94  ? 1.02944 1.14093 0.87100 -0.02882 -0.03970 0.15852  94  ARG A NH1 
798  N NH2 . ARG A 94  ? 0.82597 1.13346 0.89891 0.03380  -0.12593 0.17623  94  ARG A NH2 
799  N N   . SER A 95  ? 0.58619 0.60117 0.56642 -0.06176 -0.10131 0.14619  95  SER A N   
800  C CA  . SER A 95  ? 0.55088 0.63289 0.54664 -0.11022 -0.09941 0.10030  95  SER A CA  
801  C C   . SER A 95  ? 0.48684 0.64060 0.52727 -0.17546 -0.07044 0.09226  95  SER A C   
802  O O   . SER A 95  ? 0.50778 0.61922 0.49304 -0.17406 -0.06621 0.11960  95  SER A O   
803  C CB  . SER A 95  ? 0.50304 0.63296 0.54311 -0.11791 -0.12487 0.07921  95  SER A CB  
804  O OG  . SER A 95  ? 0.63854 0.69728 0.52180 -0.15529 -0.10869 0.07739  95  SER A OG  
805  N N   . LEU A 96  ? 0.46726 0.64279 0.51290 -0.18331 -0.02528 0.06450  96  LEU A N   
806  C CA  . LEU A 96  ? 0.52808 0.65074 0.50292 -0.15434 -0.06731 0.12605  96  LEU A CA  
807  C C   . LEU A 96  ? 0.55262 0.69528 0.53428 -0.15765 -0.15202 0.11783  96  LEU A C   
808  O O   . LEU A 96  ? 0.65006 0.67862 0.52411 -0.22758 -0.09971 0.14152  96  LEU A O   
809  C CB  . LEU A 96  ? 0.60959 0.67819 0.50583 -0.23315 -0.07210 0.12850  96  LEU A CB  
810  C CG  . LEU A 96  ? 0.51567 0.66393 0.50899 -0.24718 -0.07009 0.10428  96  LEU A CG  
811  C CD1 . LEU A 96  ? 0.45558 0.66650 0.53538 -0.20106 -0.04278 0.09767  96  LEU A CD1 
812  C CD2 . LEU A 96  ? 0.43257 0.64529 0.48981 -0.17007 -0.01158 0.12642  96  LEU A CD2 
813  N N   . GLU A 97  ? 0.55144 0.71669 0.57573 -0.16807 -0.10371 0.09648  97  GLU A N   
814  C CA  . GLU A 97  ? 0.58657 0.71836 0.62630 -0.12865 -0.05657 0.01171  97  GLU A CA  
815  C C   . GLU A 97  ? 0.67576 0.68430 0.58746 -0.14690 -0.06529 -0.01730 97  GLU A C   
816  O O   . GLU A 97  ? 0.89686 0.62083 0.62299 -0.14721 -0.06446 -0.01724 97  GLU A O   
817  C CB  . GLU A 97  ? 0.60381 0.81794 0.70467 -0.07671 -0.03634 -0.02427 97  GLU A CB  
818  C CG  . GLU A 97  ? 0.86880 0.94676 0.80991 -0.05266 -0.03377 -0.02744 97  GLU A CG  
819  C CD  . GLU A 97  ? 0.96892 1.06412 0.88037 -0.05868 -0.03820 -0.01154 97  GLU A CD  
820  O OE1 . GLU A 97  ? 1.08465 1.02927 0.91602 -0.09268 -0.05920 0.00916  97  GLU A OE1 
821  O OE2 . GLU A 97  ? 0.89597 1.11793 0.90974 -0.01022 -0.06807 -0.04504 97  GLU A OE2 
822  N N   . GLU A 98  ? 0.60176 0.71881 0.52417 -0.11066 -0.07922 0.00141  98  GLU A N   
823  C CA  . GLU A 98  ? 0.68850 0.73783 0.51686 -0.09958 -0.06801 0.03884  98  GLU A CA  
824  C C   . GLU A 98  ? 0.69751 0.69174 0.43436 -0.10264 -0.02535 0.04423  98  GLU A C   
825  O O   . GLU A 98  ? 0.67077 0.75034 0.39888 -0.18315 -0.04597 0.01845  98  GLU A O   
826  C CB  . GLU A 98  ? 0.72151 0.78207 0.57796 -0.06620 -0.07736 0.05326  98  GLU A CB  
827  C CG  . GLU A 98  ? 0.76052 0.83549 0.61849 -0.07623 -0.11175 0.01629  98  GLU A CG  
828  C CD  . GLU A 98  ? 0.92543 0.87205 0.67801 -0.05067 -0.18716 -0.01776 98  GLU A CD  
829  O OE1 . GLU A 98  ? 1.12177 0.91123 0.71892 -0.03910 -0.19014 -0.06550 98  GLU A OE1 
830  O OE2 . GLU A 98  ? 0.84779 0.83564 0.67953 -0.10293 -0.23140 -0.00911 98  GLU A OE2 
831  N N   . PHE A 99  ? 0.61690 0.60357 0.42846 -0.12924 -0.09256 0.04046  99  PHE A N   
832  C CA  . PHE A 99  ? 0.57362 0.55928 0.42492 -0.08687 -0.04506 0.05312  99  PHE A CA  
833  C C   . PHE A 99  ? 0.57864 0.51791 0.48129 -0.12118 -0.00510 0.02697  99  PHE A C   
834  O O   . PHE A 99  ? 0.64798 0.47331 0.56333 -0.10871 -0.05103 -0.00344 99  PHE A O   
835  C CB  . PHE A 99  ? 0.53860 0.57904 0.42235 -0.00242 -0.00454 0.05336  99  PHE A CB  
836  C CG  . PHE A 99  ? 0.47899 0.55606 0.42164 -0.02309 -0.01022 0.05317  99  PHE A CG  
837  C CD1 . PHE A 99  ? 0.40415 0.54502 0.42794 -0.01823 -0.03706 0.05734  99  PHE A CD1 
838  C CD2 . PHE A 99  ? 0.46894 0.50321 0.42308 -0.03034 0.01400  0.08461  99  PHE A CD2 
839  C CE1 . PHE A 99  ? 0.40112 0.52384 0.43693 -0.01080 -0.00158 0.12716  99  PHE A CE1 
840  C CE2 . PHE A 99  ? 0.38628 0.52045 0.40249 -0.03385 0.08611  0.09453  99  PHE A CE2 
841  C CZ  . PHE A 99  ? 0.42613 0.55688 0.42393 -0.07641 0.03261  0.11866  99  PHE A CZ  
842  N N   . ASN A 100 ? 0.64666 0.55765 0.45594 -0.07372 0.00792  0.03627  100 ASN A N   
843  C CA  . ASN A 100 ? 0.63658 0.53958 0.51736 0.00690  -0.06314 0.04083  100 ASN A CA  
844  C C   . ASN A 100 ? 0.60316 0.50156 0.51270 0.03429  -0.06270 0.05244  100 ASN A C   
845  O O   . ASN A 100 ? 0.69063 0.59744 0.54645 -0.06576 -0.06696 0.06025  100 ASN A O   
846  C CB  . ASN A 100 ? 0.82564 0.61587 0.56455 -0.07063 -0.01501 0.00518  100 ASN A CB  
847  C CG  . ASN A 100 ? 1.09886 0.65474 0.64360 -0.11648 0.03023  -0.03270 100 ASN A CG  
848  O OD1 . ASN A 100 ? 1.34389 0.66087 0.70305 -0.03043 0.01667  -0.05382 100 ASN A OD1 
849  N ND2 . ASN A 100 ? 1.03963 0.67371 0.64896 -0.09583 0.01296  -0.06389 100 ASN A ND2 
850  N N   . ASP A 101 ? 0.51450 0.41917 0.47832 -0.02005 -0.00307 0.07830  101 ASP A N   
851  C CA  . ASP A 101 ? 0.53892 0.44114 0.45072 -0.07933 0.11095  0.05321  101 ASP A CA  
852  C C   . ASP A 101 ? 0.51294 0.45042 0.44424 -0.09451 0.04290  0.05578  101 ASP A C   
853  O O   . ASP A 101 ? 0.49148 0.46232 0.46871 -0.09192 0.00466  0.02725  101 ASP A O   
854  C CB  . ASP A 101 ? 0.73189 0.48700 0.47966 -0.10757 0.16644  0.00937  101 ASP A CB  
855  C CG  . ASP A 101 ? 0.97888 0.54204 0.52096 -0.08223 0.19021  0.00563  101 ASP A CG  
856  O OD1 . ASP A 101 ? 1.05155 0.58329 0.59001 -0.10339 0.18602  -0.01761 101 ASP A OD1 
857  O OD2 . ASP A 101 ? 1.11470 0.56243 0.51900 -0.04482 0.09405  -0.00493 101 ASP A OD2 
858  N N   . VAL A 102 ? 0.55711 0.41734 0.43318 -0.02972 -0.00061 -0.03029 102 VAL A N   
859  C CA  . VAL A 102 ? 0.50420 0.39773 0.42077 -0.07959 0.04341  0.00592  102 VAL A CA  
860  C C   . VAL A 102 ? 0.44703 0.35301 0.42941 -0.08808 0.03454  0.01385  102 VAL A C   
861  O O   . VAL A 102 ? 0.50289 0.39331 0.47225 -0.06027 0.11225  0.00961  102 VAL A O   
862  C CB  . VAL A 102 ? 0.52113 0.47214 0.42122 -0.15099 0.10157  0.04842  102 VAL A CB  
863  C CG1 . VAL A 102 ? 0.62997 0.46830 0.39499 -0.09238 0.12833  0.02273  102 VAL A CG1 
864  C CG2 . VAL A 102 ? 0.52410 0.51991 0.47418 -0.10527 0.02472  0.11342  102 VAL A CG2 
865  N N   . TYR A 103 ? 0.39797 0.27230 0.36474 -0.04057 0.00132  0.04303  103 TYR A N   
866  C CA  . TYR A 103 ? 0.42874 0.25449 0.33957 -0.08710 -0.01123 0.07348  103 TYR A CA  
867  C C   . TYR A 103 ? 0.36737 0.32433 0.35250 -0.07250 -0.00791 0.04595  103 TYR A C   
868  O O   . TYR A 103 ? 0.40301 0.36467 0.37804 0.01775  0.02504  0.04429  103 TYR A O   
869  C CB  . TYR A 103 ? 0.45585 0.38230 0.32695 -0.07490 0.03167  0.04857  103 TYR A CB  
870  C CG  . TYR A 103 ? 0.50247 0.37116 0.31414 -0.05560 0.03231  -0.01181 103 TYR A CG  
871  C CD1 . TYR A 103 ? 0.45926 0.29960 0.32136 0.02227  -0.01790 0.04436  103 TYR A CD1 
872  C CD2 . TYR A 103 ? 0.44789 0.32960 0.31446 -0.00286 0.06326  -0.01193 103 TYR A CD2 
873  C CE1 . TYR A 103 ? 0.57167 0.33903 0.36909 -0.04056 0.02022  0.02550  103 TYR A CE1 
874  C CE2 . TYR A 103 ? 0.48359 0.34602 0.30764 -0.02462 0.02248  0.00038  103 TYR A CE2 
875  C CZ  . TYR A 103 ? 0.53293 0.36130 0.36366 0.00452  0.02525  0.01544  103 TYR A CZ  
876  O OH  . TYR A 103 ? 0.58060 0.39287 0.38112 0.02663  0.07118  0.05717  103 TYR A OH  
877  N N   . LEU A 104 ? 0.29979 0.39759 0.32095 0.00503  -0.02632 0.01153  104 LEU A N   
878  C CA  . LEU A 104 ? 0.37320 0.39445 0.35896 -0.01711 -0.01343 0.04690  104 LEU A CA  
879  C C   . LEU A 104 ? 0.44728 0.32803 0.39279 -0.04026 0.03629  -0.02029 104 LEU A C   
880  O O   . LEU A 104 ? 0.44815 0.35927 0.42095 -0.02618 0.06912  0.05159  104 LEU A O   
881  C CB  . LEU A 104 ? 0.36823 0.37657 0.36758 -0.05678 -0.00959 0.06084  104 LEU A CB  
882  C CG  . LEU A 104 ? 0.33987 0.32880 0.39965 0.06230  0.06028  0.05433  104 LEU A CG  
883  C CD1 . LEU A 104 ? 0.39249 0.36579 0.44858 0.07539  0.05587  0.04559  104 LEU A CD1 
884  C CD2 . LEU A 104 ? 0.41745 0.37596 0.36079 -0.00661 0.04047  0.07264  104 LEU A CD2 
885  N N   . VAL A 105 ? 0.33004 0.31805 0.39697 -0.02284 0.03057  0.01380  105 VAL A N   
886  C CA  . VAL A 105 ? 0.38159 0.27984 0.38127 0.00199  0.01560  0.10623  105 VAL A CA  
887  C C   . VAL A 105 ? 0.46461 0.39177 0.39142 -0.00217 0.01304  0.06191  105 VAL A C   
888  O O   . VAL A 105 ? 0.35573 0.34663 0.39591 -0.02133 0.00693  0.07121  105 VAL A O   
889  C CB  . VAL A 105 ? 0.34615 0.24832 0.38069 -0.00440 -0.02285 0.10940  105 VAL A CB  
890  C CG1 . VAL A 105 ? 0.44929 0.27620 0.40597 -0.04380 -0.00593 0.10907  105 VAL A CG1 
891  C CG2 . VAL A 105 ? 0.37397 0.35582 0.31504 -0.00192 -0.06491 0.01659  105 VAL A CG2 
892  N N   . THR A 106 ? 0.39381 0.37907 0.41448 0.00174  -0.03437 0.05004  106 THR A N   
893  C CA  . THR A 106 ? 0.32249 0.34774 0.44324 0.00925  -0.06430 0.06978  106 THR A CA  
894  C C   . THR A 106 ? 0.36228 0.43578 0.45309 -0.01702 -0.03264 0.04907  106 THR A C   
895  O O   . THR A 106 ? 0.39910 0.47731 0.42572 0.02032  -0.02045 0.06357  106 THR A O   
896  C CB  . THR A 106 ? 0.40470 0.37483 0.44515 0.02614  -0.01150 0.06865  106 THR A CB  
897  O OG1 . THR A 106 ? 0.45953 0.40483 0.46510 0.06180  0.04556  0.05966  106 THR A OG1 
898  C CG2 . THR A 106 ? 0.42193 0.34756 0.42746 -0.02096 -0.06793 0.01132  106 THR A CG2 
899  N N   . HIS A 107 ? 0.38005 0.51042 0.50737 0.01531  -0.01810 0.05380  107 HIS A N   
900  C CA  . HIS A 107 ? 0.39870 0.55765 0.54500 -0.03578 -0.05098 0.04181  107 HIS A CA  
901  C C   . HIS A 107 ? 0.39484 0.59665 0.55060 0.04822  -0.04256 0.08658  107 HIS A C   
902  O O   . HIS A 107 ? 0.37490 0.55403 0.55911 -0.01829 -0.07614 0.09957  107 HIS A O   
903  C CB  . HIS A 107 ? 0.50796 0.57128 0.57817 -0.07972 -0.13223 -0.00610 107 HIS A CB  
904  C CG  . HIS A 107 ? 0.60307 0.62107 0.63995 -0.02999 -0.17587 -0.00993 107 HIS A CG  
905  N ND1 . HIS A 107 ? 0.73283 0.63094 0.66133 0.02408  -0.20904 0.03057  107 HIS A ND1 
906  C CD2 . HIS A 107 ? 0.73019 0.69245 0.70587 -0.04455 -0.16878 -0.02794 107 HIS A CD2 
907  C CE1 . HIS A 107 ? 0.74936 0.63635 0.66878 0.02542  -0.21445 0.04148  107 HIS A CE1 
908  N NE2 . HIS A 107 ? 0.78685 0.61778 0.68478 0.02538  -0.15201 -0.02643 107 HIS A NE2 
909  N N   . LEU A 108 ? 0.31946 0.64885 0.56696 0.07321  -0.04030 0.13857  108 LEU A N   
910  C CA  . LEU A 108 ? 0.31737 0.65582 0.58882 0.07113  -0.06486 0.17000  108 LEU A CA  
911  C C   . LEU A 108 ? 0.39595 0.71912 0.63944 0.03241  -0.07219 0.21387  108 LEU A C   
912  O O   . LEU A 108 ? 0.40874 0.74726 0.68375 -0.10344 -0.10391 0.20919  108 LEU A O   
913  C CB  . LEU A 108 ? 0.35525 0.67652 0.57608 -0.00154 0.00399  0.14455  108 LEU A CB  
914  C CG  . LEU A 108 ? 0.44966 0.69229 0.56906 -0.06037 0.02853  0.12471  108 LEU A CG  
915  C CD1 . LEU A 108 ? 0.41977 0.64107 0.55022 -0.00510 0.06753  0.09917  108 LEU A CD1 
916  C CD2 . LEU A 108 ? 0.47694 0.72105 0.55950 -0.05563 0.02553  0.12473  108 LEU A CD2 
917  N N   . MET A 109 ? 0.40477 0.78124 0.66485 0.08663  0.02916  0.25515  109 MET A N   
918  C CA  . MET A 109 ? 0.49645 0.89597 0.73667 0.09275  0.08624  0.23830  109 MET A CA  
919  C C   . MET A 109 ? 0.60440 0.90706 0.79590 0.06227  0.01917  0.15049  109 MET A C   
920  O O   . MET A 109 ? 0.54532 0.94991 0.82574 0.12984  0.01106  0.08530  109 MET A O   
921  C CB  . MET A 109 ? 0.74848 0.98912 0.76681 0.09074  0.05405  0.30948  109 MET A CB  
922  C CG  . MET A 109 ? 0.83645 1.05727 0.80648 0.06786  0.00874  0.33383  109 MET A CG  
923  S SD  . MET A 109 ? 0.72528 1.12084 0.85912 0.02267  0.04865  0.34569  109 MET A SD  
924  C CE  . MET A 109 ? 0.73682 1.14446 0.86577 -0.07068 -0.00257 0.40312  109 MET A CE  
925  N N   . GLY A 110 ? 0.61626 0.85814 0.81129 0.05292  0.04444  0.18366  110 GLY A N   
926  C CA  . GLY A 110 ? 0.69773 0.81396 0.83098 0.03643  -0.00590 0.19617  110 GLY A CA  
927  C C   . GLY A 110 ? 0.68154 0.79095 0.83260 -0.01631 0.00121  0.14502  110 GLY A C   
928  O O   . GLY A 110 ? 0.67149 0.80196 0.86968 -0.05632 -0.03660 0.09459  110 GLY A O   
929  N N   . ALA A 111 ? 0.64987 0.70294 0.75034 -0.10661 0.06946  0.18341  111 ALA A N   
930  C CA  . ALA A 111 ? 0.60902 0.61767 0.67829 -0.06974 0.13063  0.22665  111 ALA A CA  
931  C C   . ALA A 111 ? 0.63440 0.53839 0.62497 0.00948  0.11613  0.17837  111 ALA A C   
932  O O   . ALA A 111 ? 0.70774 0.43777 0.60109 0.10767  0.19356  0.12750  111 ALA A O   
933  C CB  . ALA A 111 ? 0.60092 0.61078 0.66257 -0.02537 0.17824  0.24118  111 ALA A CB  
934  N N   . ASP A 112 ? 0.43758 0.60282 0.61590 -0.08919 0.06408  0.18044  112 ASP A N   
935  C CA  . ASP A 112 ? 0.37816 0.59263 0.59182 0.07872  0.06119  0.19876  112 ASP A CA  
936  C C   . ASP A 112 ? 0.47921 0.58314 0.61301 0.15974  0.22109  0.16032  112 ASP A C   
937  O O   . ASP A 112 ? 0.68843 0.59310 0.64317 0.15601  0.21431  0.18462  112 ASP A O   
938  C CB  . ASP A 112 ? 0.32765 0.64807 0.60972 0.11071  0.09069  0.15097  112 ASP A CB  
939  C CG  . ASP A 112 ? 0.58709 0.72650 0.62217 -0.00067 0.13046  0.11625  112 ASP A CG  
940  O OD1 . ASP A 112 ? 0.64871 0.79611 0.58904 -0.03823 0.04523  0.09204  112 ASP A OD1 
941  O OD2 . ASP A 112 ? 0.66852 0.70788 0.65466 -0.09122 0.14506  0.12303  112 ASP A OD2 
942  N N   . LEU A 113 ? 0.44718 0.55463 0.62593 0.04889  0.14730  0.17395  113 LEU A N   
943  C CA  . LEU A 113 ? 0.37758 0.61270 0.65651 0.09904  0.09019  0.16450  113 LEU A CA  
944  C C   . LEU A 113 ? 0.42801 0.74265 0.71261 0.13471  0.09973  0.13681  113 LEU A C   
945  O O   . LEU A 113 ? 0.55185 0.78500 0.69945 0.12275  0.04367  0.17066  113 LEU A O   
946  C CB  . LEU A 113 ? 0.49788 0.60880 0.63438 -0.00427 0.03967  0.13715  113 LEU A CB  
947  C CG  . LEU A 113 ? 0.60221 0.56824 0.61702 -0.06270 0.04013  0.12946  113 LEU A CG  
948  C CD1 . LEU A 113 ? 0.61108 0.56070 0.63826 0.08753  0.06522  0.10182  113 LEU A CD1 
949  C CD2 . LEU A 113 ? 0.60375 0.53535 0.56547 -0.13433 0.01849  0.16437  113 LEU A CD2 
950  N N   . ASN A 114 ? 0.52198 0.80627 0.76475 0.09898  0.15961  0.09736  114 ASN A N   
951  C CA  . ASN A 114 ? 0.75632 0.86938 0.83504 0.05252  0.12549  0.06133  114 ASN A CA  
952  C C   . ASN A 114 ? 0.91505 0.97547 0.89036 0.05251  0.05531  0.04172  114 ASN A C   
953  O O   . ASN A 114 ? 1.08740 0.97449 0.88435 0.09944  0.02364  -0.00406 114 ASN A O   
954  C CB  . ASN A 114 ? 0.87127 0.85286 0.85313 0.03460  0.15880  0.01603  114 ASN A CB  
955  C CG  . ASN A 114 ? 0.90605 0.84906 0.85535 -0.01735 0.21820  -0.03400 114 ASN A CG  
956  O OD1 . ASN A 114 ? 0.74765 0.82819 0.86410 -0.05883 0.35007  -0.07317 114 ASN A OD1 
957  N ND2 . ASN A 114 ? 1.00906 0.84520 0.85868 -0.09979 0.12694  -0.01365 114 ASN A ND2 
958  N N   . ASN A 115 ? 0.88565 1.03595 0.94964 0.05082  0.04238  0.08511  115 ASN A N   
959  C CA  . ASN A 115 ? 0.90977 1.06204 1.00543 -0.01290 0.06501  0.10788  115 ASN A CA  
960  C C   . ASN A 115 ? 1.07499 1.11746 1.07550 -0.00260 0.01558  0.07781  115 ASN A C   
961  O O   . ASN A 115 ? 1.09221 1.15184 1.09291 -0.01250 0.00738  0.08361  115 ASN A O   
962  C CB  . ASN A 115 ? 0.85342 1.05356 0.99047 0.01451  0.15193  0.16557  115 ASN A CB  
963  C CG  . ASN A 115 ? 0.87638 1.06064 0.98665 0.02450  0.25544  0.20955  115 ASN A CG  
964  O OD1 . ASN A 115 ? 0.78287 1.03307 0.96921 -0.01671 0.33846  0.26181  115 ASN A OD1 
965  N ND2 . ASN A 115 ? 0.88331 1.09195 0.99844 0.09791  0.21960  0.18332  115 ASN A ND2 
966  N N   . ILE A 116 ? 1.18824 1.16317 1.13369 0.04804  -0.00484 0.04434  116 ILE A N   
967  C CA  . ILE A 116 ? 1.21275 1.20689 1.20692 0.11468  -0.02920 -0.00150 116 ILE A CA  
968  C C   . ILE A 116 ? 1.29785 1.27166 1.26110 0.02347  -0.02909 -0.00381 116 ILE A C   
969  O O   . ILE A 116 ? 1.42244 1.27775 1.27215 0.01296  -0.03785 -0.00450 116 ILE A O   
970  C CB  . ILE A 116 ? 1.09415 1.18504 1.22327 0.28979  -0.04482 -0.03152 116 ILE A CB  
971  C CG1 . ILE A 116 ? 1.02676 1.17310 1.23759 0.36477  -0.09839 -0.03669 116 ILE A CG1 
972  C CG2 . ILE A 116 ? 1.06242 1.19429 1.21306 0.37973  -0.02043 -0.05807 116 ILE A CG2 
973  C CD1 . ILE A 116 ? 1.06372 1.17787 1.23668 0.38873  -0.10661 -0.03014 116 ILE A CD1 
974  N N   . VAL A 117 ? 1.23436 1.34538 1.29472 -0.04329 0.03122  0.01196  117 VAL A N   
975  C CA  . VAL A 117 ? 1.25600 1.41685 1.32622 -0.08305 0.13440  0.02522  117 VAL A CA  
976  C C   . VAL A 117 ? 1.41012 1.49129 1.34848 -0.05646 0.21905  0.03498  117 VAL A C   
977  O O   . VAL A 117 ? 1.45039 1.52515 1.35061 -0.07216 0.25348  0.03348  117 VAL A O   
978  C CB  . VAL A 117 ? 1.10064 1.41201 1.32890 -0.13017 0.16242  0.03565  117 VAL A CB  
979  C CG1 . VAL A 117 ? 1.17395 1.42496 1.34223 -0.12710 0.11236  0.03658  117 VAL A CG1 
980  C CG2 . VAL A 117 ? 0.89125 1.39001 1.31657 -0.15384 0.20666  0.05874  117 VAL A CG2 
981  N N   . LYS A 118 ? 1.50452 1.50912 1.36699 -0.00327 0.21157  0.04608  118 LYS A N   
982  C CA  . LYS A 118 ? 1.57223 1.49314 1.37644 0.07611  0.15780  0.03288  118 LYS A CA  
983  C C   . LYS A 118 ? 1.71056 1.62607 1.41826 0.06885  0.10111  0.03923  118 LYS A C   
984  O O   . LYS A 118 ? 1.68556 1.66805 1.40660 0.11285  0.11294  0.01977  118 LYS A O   
985  C CB  . LYS A 118 ? 1.44140 1.33453 1.33058 0.15529  0.14990  0.01100  118 LYS A CB  
986  C CG  . LYS A 118 ? 1.27394 1.19616 1.28518 0.20193  0.12342  0.03287  118 LYS A CG  
987  C CD  . LYS A 118 ? 1.09556 1.09051 1.24537 0.19344  0.08170  0.06594  118 LYS A CD  
988  C CE  . LYS A 118 ? 0.88730 1.00160 1.21499 0.19164  0.09720  0.10123  118 LYS A CE  
989  N NZ  . LYS A 118 ? 0.82587 0.95996 1.18232 0.16016  0.08413  0.10621  118 LYS A NZ  
990  N N   . CYS A 119 ? 1.81389 1.67312 1.46127 0.00872  0.03466  0.06472  119 CYS A N   
991  C CA  . CYS A 119 ? 1.81950 1.69393 1.47334 -0.04691 -0.02139 0.09540  119 CYS A CA  
992  C C   . CYS A 119 ? 1.72053 1.67882 1.45309 -0.07185 -0.02453 0.08180  119 CYS A C   
993  O O   . CYS A 119 ? 1.71816 1.70456 1.45560 -0.09817 -0.02614 0.08267  119 CYS A O   
994  C CB  . CYS A 119 ? 1.88261 1.72277 1.48689 -0.05454 -0.09147 0.14115  119 CYS A CB  
995  S SG  . CYS A 119 ? 1.92660 1.74082 1.49438 -0.05616 -0.12453 0.16796  119 CYS A SG  
996  N N   . GLN A 120 ? 1.58592 1.62684 1.41929 -0.05483 -0.00009 0.08128  120 GLN A N   
997  C CA  . GLN A 120 ? 1.44995 1.55358 1.38777 -0.01702 0.02753  0.10370  120 GLN A CA  
998  C C   . GLN A 120 ? 1.43231 1.59961 1.35236 0.01118  0.02270  0.05833  120 GLN A C   
999  O O   . GLN A 120 ? 1.37365 1.62190 1.37065 0.00539  0.00468  0.04385  120 GLN A O   
1000 C CB  . GLN A 120 ? 1.35238 1.42206 1.39415 -0.00264 0.06655  0.16737  120 GLN A CB  
1001 C CG  . GLN A 120 ? 1.28325 1.30950 1.39535 0.03517  0.10544  0.21936  120 GLN A CG  
1002 C CD  . GLN A 120 ? 1.25912 1.22583 1.38648 0.04677  0.16009  0.27069  120 GLN A CD  
1003 O OE1 . GLN A 120 ? 1.20923 1.19250 1.36695 0.02092  0.22797  0.30123  120 GLN A OE1 
1004 N NE2 . GLN A 120 ? 1.28864 1.20312 1.39325 0.08773  0.15428  0.27752  120 GLN A NE2 
1005 N N   . LYS A 121 ? 1.49226 1.59109 1.29441 0.05251  0.04712  0.02478  121 LYS A N   
1006 C CA  . LYS A 121 ? 1.48414 1.55953 1.23451 0.08400  0.10876  -0.00090 121 LYS A CA  
1007 C C   . LYS A 121 ? 1.49778 1.46995 1.16759 0.06237  0.20195  -0.00195 121 LYS A C   
1008 O O   . LYS A 121 ? 1.62534 1.48011 1.18226 0.08464  0.23811  0.00442  121 LYS A O   
1009 C CB  . LYS A 121 ? 1.41836 1.59417 1.24186 0.12488  0.06739  -0.01865 121 LYS A CB  
1010 C CG  . LYS A 121 ? 1.34626 1.62049 1.24054 0.16640  0.04630  -0.01791 121 LYS A CG  
1011 C CD  . LYS A 121 ? 1.27615 1.62884 1.23515 0.21039  0.06524  -0.01791 121 LYS A CD  
1012 C CE  . LYS A 121 ? 1.21615 1.62139 1.22166 0.27507  0.11737  -0.02333 121 LYS A CE  
1013 N NZ  . LYS A 121 ? 1.18160 1.60368 1.20138 0.33674  0.14447  -0.01764 121 LYS A NZ  
1014 N N   . LEU A 122 ? 1.34055 1.35105 1.08428 0.00811  0.18944  -0.01003 122 LEU A N   
1015 C CA  . LEU A 122 ? 1.13677 1.20747 0.99902 -0.03033 0.16529  -0.01265 122 LEU A CA  
1016 C C   . LEU A 122 ? 1.01030 1.06124 0.91119 -0.08743 0.18626  -0.02592 122 LEU A C   
1017 O O   . LEU A 122 ? 1.08296 1.02782 0.88834 -0.08173 0.23828  -0.05748 122 LEU A O   
1018 C CB  . LEU A 122 ? 1.04997 1.19986 0.99615 -0.06750 0.12203  0.00403  122 LEU A CB  
1019 C CG  . LEU A 122 ? 1.01306 1.19017 1.00611 -0.05023 0.08937  0.00464  122 LEU A CG  
1020 C CD1 . LEU A 122 ? 1.02661 1.20096 1.00327 -0.07044 0.09458  -0.00430 122 LEU A CD1 
1021 C CD2 . LEU A 122 ? 0.93448 1.18798 1.00668 0.02261  0.04002  0.00422  122 LEU A CD2 
1022 N N   . THR A 123 ? 0.78846 0.95738 0.83951 -0.12787 0.12289  0.01068  123 THR A N   
1023 C CA  . THR A 123 ? 0.67589 0.88360 0.77167 -0.13237 0.05141  0.04148  123 THR A CA  
1024 C C   . THR A 123 ? 0.69262 0.76387 0.71241 -0.15475 0.00747  0.04174  123 THR A C   
1025 O O   . THR A 123 ? 0.59862 0.66153 0.68614 -0.22073 0.04676  -0.00888 123 THR A O   
1026 C CB  . THR A 123 ? 0.68563 0.91470 0.78724 -0.12389 0.02125  0.08983  123 THR A CB  
1027 O OG1 . THR A 123 ? 0.45703 0.88391 0.81765 -0.21348 -0.02609 0.09595  123 THR A OG1 
1028 C CG2 . THR A 123 ? 0.82628 0.94704 0.78948 -0.09894 0.02408  0.10568  123 THR A CG2 
1029 N N   . ASP A 124 ? 0.67653 0.74489 0.70888 -0.16457 0.04553  0.06104  124 ASP A N   
1030 C CA  . ASP A 124 ? 0.58642 0.69311 0.66667 -0.12551 -0.00495 0.03155  124 ASP A CA  
1031 C C   . ASP A 124 ? 0.40602 0.64169 0.64472 -0.09171 -0.07839 -0.02170 124 ASP A C   
1032 O O   . ASP A 124 ? 0.41779 0.56633 0.64580 -0.06681 -0.11683 -0.09709 124 ASP A O   
1033 C CB  . ASP A 124 ? 0.52309 0.65208 0.64947 -0.04786 -0.03116 0.05774  124 ASP A CB  
1034 C CG  . ASP A 124 ? 0.58299 0.58739 0.63885 -0.00773 -0.04259 -0.00169 124 ASP A CG  
1035 O OD1 . ASP A 124 ? 0.50174 0.54650 0.60267 -0.08159 0.01056  0.00355  124 ASP A OD1 
1036 O OD2 . ASP A 124 ? 0.55436 0.53209 0.67753 -0.01095 0.02656  -0.04847 124 ASP A OD2 
1037 N N   . ASP A 125 ? 0.44385 0.64421 0.63770 -0.13044 -0.11192 -0.04192 125 ASP A N   
1038 C CA  . ASP A 125 ? 0.43914 0.64236 0.66475 -0.14529 -0.14039 -0.05683 125 ASP A CA  
1039 C C   . ASP A 125 ? 0.46459 0.49381 0.60583 -0.10804 -0.09252 -0.03680 125 ASP A C   
1040 O O   . ASP A 125 ? 0.43980 0.51546 0.59185 -0.09224 -0.03516 -0.06045 125 ASP A O   
1041 C CB  . ASP A 125 ? 0.81995 0.82535 0.74730 -0.12214 -0.08294 -0.08807 125 ASP A CB  
1042 C CG  . ASP A 125 ? 1.07611 1.03914 0.81862 -0.03681 -0.02813 -0.07459 125 ASP A CG  
1043 O OD1 . ASP A 125 ? 1.10587 1.11528 0.83297 -0.05056 -0.00201 -0.08909 125 ASP A OD1 
1044 O OD2 . ASP A 125 ? 1.21592 1.09410 0.86105 -0.03503 -0.02991 -0.04571 125 ASP A OD2 
1045 N N   . HIS A 126 ? 0.51259 0.44127 0.61938 -0.16081 -0.06857 0.04289  126 HIS A N   
1046 C CA  . HIS A 126 ? 0.57751 0.44690 0.63721 -0.12993 -0.03308 0.14428  126 HIS A CA  
1047 C C   . HIS A 126 ? 0.44797 0.42401 0.54403 -0.04341 0.00428  0.02057  126 HIS A C   
1048 O O   . HIS A 126 ? 0.43330 0.42320 0.53468 -0.03283 -0.01335 -0.02093 126 HIS A O   
1049 C CB  . HIS A 126 ? 0.64425 0.57447 0.75585 -0.23206 0.00969  0.29370  126 HIS A CB  
1050 C CG  . HIS A 126 ? 0.79422 0.77397 0.90544 -0.16962 -0.02905 0.37064  126 HIS A CG  
1051 N ND1 . HIS A 126 ? 0.79490 0.83534 0.96606 -0.22162 -0.06074 0.40882  126 HIS A ND1 
1052 C CD2 . HIS A 126 ? 0.80250 0.83950 0.96637 -0.13974 -0.06228 0.42408  126 HIS A CD2 
1053 C CE1 . HIS A 126 ? 0.79354 0.87428 0.99042 -0.17034 -0.04999 0.44570  126 HIS A CE1 
1054 N NE2 . HIS A 126 ? 0.81479 0.86716 0.99360 -0.13658 -0.06261 0.44017  126 HIS A NE2 
1055 N N   . VAL A 127 ? 0.39694 0.37615 0.49612 -0.03312 -0.00359 -0.02584 127 VAL A N   
1056 C CA  . VAL A 127 ? 0.26627 0.39733 0.46952 0.01098  0.01070  -0.04408 127 VAL A CA  
1057 C C   . VAL A 127 ? 0.35737 0.38175 0.47256 -0.01336 0.01495  -0.05364 127 VAL A C   
1058 O O   . VAL A 127 ? 0.34937 0.37698 0.50390 -0.00622 -0.05275 -0.07681 127 VAL A O   
1059 C CB  . VAL A 127 ? 0.28397 0.43727 0.48961 -0.02225 0.01922  -0.02526 127 VAL A CB  
1060 C CG1 . VAL A 127 ? 0.36252 0.39532 0.45933 -0.05074 0.03522  0.00473  127 VAL A CG1 
1061 C CG2 . VAL A 127 ? 0.34322 0.43963 0.50486 -0.01553 0.06194  -0.06017 127 VAL A CG2 
1062 N N   . GLN A 128 ? 0.34618 0.37602 0.46697 -0.01711 0.04328  -0.05429 128 GLN A N   
1063 C CA  . GLN A 128 ? 0.36267 0.33023 0.47810 -0.05905 -0.09217 -0.05624 128 GLN A CA  
1064 C C   . GLN A 128 ? 0.33630 0.34283 0.44731 -0.05026 -0.03162 -0.03335 128 GLN A C   
1065 O O   . GLN A 128 ? 0.33196 0.39929 0.39371 -0.06071 0.00873  -0.01989 128 GLN A O   
1066 C CB  . GLN A 128 ? 0.32475 0.38538 0.50978 -0.05950 -0.13591 -0.04623 128 GLN A CB  
1067 C CG  . GLN A 128 ? 0.55310 0.43004 0.50082 -0.06016 -0.20124 -0.02226 128 GLN A CG  
1068 C CD  . GLN A 128 ? 0.78286 0.48239 0.52604 0.00289  -0.20374 -0.08309 128 GLN A CD  
1069 O OE1 . GLN A 128 ? 0.80566 0.43809 0.51846 0.08273  -0.17819 -0.09807 128 GLN A OE1 
1070 N NE2 . GLN A 128 ? 0.73108 0.56800 0.56311 0.04437  -0.14874 -0.06509 128 GLN A NE2 
1071 N N   . PHE A 129 ? 0.48037 0.39324 0.42407 -0.01818 -0.03566 0.00383  129 PHE A N   
1072 C CA  . PHE A 129 ? 0.43711 0.36485 0.43977 0.03417  -0.08358 0.06123  129 PHE A CA  
1073 C C   . PHE A 129 ? 0.36437 0.36780 0.40927 -0.00439 -0.06607 0.00126  129 PHE A C   
1074 O O   . PHE A 129 ? 0.33776 0.38313 0.40016 -0.02130 -0.06400 -0.03034 129 PHE A O   
1075 C CB  . PHE A 129 ? 0.38705 0.36828 0.48772 -0.04492 -0.01439 0.06090  129 PHE A CB  
1076 C CG  . PHE A 129 ? 0.41852 0.39784 0.53613 0.01241  0.02286  0.05207  129 PHE A CG  
1077 C CD1 . PHE A 129 ? 0.57145 0.41995 0.56647 0.00005  0.05217  0.05863  129 PHE A CD1 
1078 C CD2 . PHE A 129 ? 0.36353 0.37419 0.54684 0.02453  -0.05317 0.03931  129 PHE A CD2 
1079 C CE1 . PHE A 129 ? 0.56306 0.44676 0.58491 -0.06060 0.05451  0.03657  129 PHE A CE1 
1080 C CE2 . PHE A 129 ? 0.43830 0.37888 0.59284 0.04261  0.02401  0.02857  129 PHE A CE2 
1081 C CZ  . PHE A 129 ? 0.42431 0.43384 0.58001 -0.03595 0.06721  0.01677  129 PHE A CZ  
1082 N N   . LEU A 130 ? 0.36603 0.32749 0.39646 -0.02648 0.03355  0.00026  130 LEU A N   
1083 C CA  . LEU A 130 ? 0.36171 0.29107 0.37790 0.02529  -0.02069 -0.02295 130 LEU A CA  
1084 C C   . LEU A 130 ? 0.36063 0.33627 0.37520 -0.05192 0.00033  -0.06421 130 LEU A C   
1085 O O   . LEU A 130 ? 0.34490 0.34454 0.37794 -0.04816 -0.01096 -0.00109 130 LEU A O   
1086 C CB  . LEU A 130 ? 0.42860 0.29482 0.39001 -0.00299 0.08041  0.00076  130 LEU A CB  
1087 C CG  . LEU A 130 ? 0.46490 0.38988 0.43892 0.02573  0.03388  0.05480  130 LEU A CG  
1088 C CD1 . LEU A 130 ? 0.47612 0.40151 0.46185 0.02698  -0.01119 0.05482  130 LEU A CD1 
1089 C CD2 . LEU A 130 ? 0.58366 0.37638 0.42937 0.04645  0.02361  0.08144  130 LEU A CD2 
1090 N N   . ILE A 131 ? 0.43514 0.32167 0.39455 -0.00670 -0.00490 -0.02781 131 ILE A N   
1091 C CA  . ILE A 131 ? 0.33398 0.33538 0.40928 0.00819  -0.01505 -0.00732 131 ILE A CA  
1092 C C   . ILE A 131 ? 0.34919 0.31906 0.37818 -0.01327 -0.03278 -0.01561 131 ILE A C   
1093 O O   . ILE A 131 ? 0.35309 0.30406 0.34824 -0.01945 -0.01868 -0.01384 131 ILE A O   
1094 C CB  . ILE A 131 ? 0.35619 0.33965 0.33932 -0.04402 0.00865  -0.00902 131 ILE A CB  
1095 C CG1 . ILE A 131 ? 0.33533 0.39943 0.32180 -0.03031 0.03323  -0.07880 131 ILE A CG1 
1096 C CG2 . ILE A 131 ? 0.34077 0.32328 0.34242 -0.01670 0.03463  -0.01896 131 ILE A CG2 
1097 C CD1 . ILE A 131 ? 0.31363 0.42886 0.35497 0.05149  0.00628  -0.11993 131 ILE A CD1 
1098 N N   . TYR A 132 ? 0.35826 0.32751 0.36071 0.02423  0.00098  0.00552  132 TYR A N   
1099 C CA  . TYR A 132 ? 0.38972 0.31202 0.38478 -0.02199 -0.03606 -0.02846 132 TYR A CA  
1100 C C   . TYR A 132 ? 0.25041 0.40250 0.38289 -0.01277 0.00268  -0.00751 132 TYR A C   
1101 O O   . TYR A 132 ? 0.27174 0.43986 0.36546 -0.02339 0.05906  -0.02151 132 TYR A O   
1102 C CB  . TYR A 132 ? 0.33437 0.31590 0.43301 -0.01681 0.00798  -0.03378 132 TYR A CB  
1103 C CG  . TYR A 132 ? 0.29018 0.40496 0.46079 0.00636  0.01515  -0.03817 132 TYR A CG  
1104 C CD1 . TYR A 132 ? 0.25016 0.45497 0.46648 0.03863  -0.00302 -0.04898 132 TYR A CD1 
1105 C CD2 . TYR A 132 ? 0.40318 0.36259 0.45718 0.05022  -0.06312 -0.04862 132 TYR A CD2 
1106 C CE1 . TYR A 132 ? 0.27362 0.41100 0.47073 0.08346  -0.06281 -0.04462 132 TYR A CE1 
1107 C CE2 . TYR A 132 ? 0.33289 0.41103 0.46603 0.07445  -0.00006 -0.08913 132 TYR A CE2 
1108 C CZ  . TYR A 132 ? 0.39571 0.39974 0.49715 0.00335  -0.02379 -0.08692 132 TYR A CZ  
1109 O OH  . TYR A 132 ? 0.49947 0.43768 0.54367 0.00309  -0.04929 -0.09823 132 TYR A OH  
1110 N N   . GLN A 133 ? 0.40286 0.31587 0.36274 0.02973  -0.02540 -0.01268 133 GLN A N   
1111 C CA  . GLN A 133 ? 0.41998 0.31202 0.36815 0.01914  -0.05705 0.02972  133 GLN A CA  
1112 C C   . GLN A 133 ? 0.43522 0.29544 0.36373 -0.04420 -0.01796 -0.00046 133 GLN A C   
1113 O O   . GLN A 133 ? 0.36754 0.33466 0.39211 -0.01183 0.01085  -0.03867 133 GLN A O   
1114 C CB  . GLN A 133 ? 0.40030 0.17985 0.37943 -0.00796 -0.02598 0.08069  133 GLN A CB  
1115 C CG  . GLN A 133 ? 0.34938 0.25944 0.40063 -0.03213 -0.01137 0.08037  133 GLN A CG  
1116 C CD  . GLN A 133 ? 0.40826 0.34812 0.44740 0.00316  -0.04803 0.03730  133 GLN A CD  
1117 O OE1 . GLN A 133 ? 0.46718 0.32574 0.44723 -0.02566 0.02769  0.05286  133 GLN A OE1 
1118 N NE2 . GLN A 133 ? 0.38239 0.36015 0.45546 0.00677  -0.08043 0.00087  133 GLN A NE2 
1119 N N   . ILE A 134 ? 0.33829 0.33547 0.37364 -0.00419 0.03882  0.01483  134 ILE A N   
1120 C CA  A ILE A 134 ? 0.33011 0.30322 0.33455 -0.04391 0.00091  0.02286  134 ILE A CA  
1121 C CA  B ILE A 134 ? 0.38201 0.39239 0.40075 0.00608  -0.00294 0.01884  134 ILE A CA  
1122 C C   . ILE A 134 ? 0.35579 0.37414 0.36860 -0.00755 -0.00036 0.02640  134 ILE A C   
1123 O O   . ILE A 134 ? 0.28519 0.40381 0.37079 -0.01249 -0.02507 0.02602  134 ILE A O   
1124 C CB  A ILE A 134 ? 0.28825 0.18090 0.25724 -0.02473 -0.01866 0.02403  134 ILE A CB  
1125 C CB  B ILE A 134 ? 0.44679 0.48118 0.43319 0.08693  -0.02001 -0.00427 134 ILE A CB  
1126 C CG1 A ILE A 134 ? 0.20430 0.16608 0.22855 0.03114  0.04130  0.03955  134 ILE A CG1 
1127 C CG1 B ILE A 134 ? 0.38823 0.50715 0.43716 0.12935  -0.03092 -0.00599 134 ILE A CG1 
1128 C CG2 A ILE A 134 ? 0.27457 0.19336 0.23944 -0.05372 -0.01050 -0.02386 134 ILE A CG2 
1129 C CG2 B ILE A 134 ? 0.55951 0.54984 0.45939 0.10106  0.04538  -0.01003 134 ILE A CG2 
1130 C CD1 A ILE A 134 ? 0.22093 0.17592 0.21193 0.04256  0.04567  -0.02873 134 ILE A CD1 
1131 C CD1 B ILE A 134 ? 0.57733 0.56809 0.44668 0.12140  0.03541  0.03283  134 ILE A CD1 
1132 N N   . LEU A 135 ? 0.37381 0.34133 0.37987 0.04655  0.03310  0.05050  135 LEU A N   
1133 C CA  . LEU A 135 ? 0.35380 0.32051 0.35147 -0.00542 -0.04470 0.04354  135 LEU A CA  
1134 C C   . LEU A 135 ? 0.24142 0.29342 0.38643 -0.03660 -0.01046 0.02522  135 LEU A C   
1135 O O   . LEU A 135 ? 0.29534 0.35098 0.40407 -0.00054 0.02624  0.04137  135 LEU A O   
1136 C CB  . LEU A 135 ? 0.25475 0.35509 0.31961 0.03328  -0.02441 0.06127  135 LEU A CB  
1137 C CG  . LEU A 135 ? 0.35289 0.33398 0.31760 -0.02189 -0.06648 0.07152  135 LEU A CG  
1138 C CD1 . LEU A 135 ? 0.31063 0.41301 0.34005 -0.01775 -0.03301 0.01556  135 LEU A CD1 
1139 C CD2 . LEU A 135 ? 0.37916 0.32762 0.29627 -0.02577 0.03234  0.05361  135 LEU A CD2 
1140 N N   . ARG A 136 ? 0.34120 0.30181 0.36002 0.02317  -0.06116 0.03727  136 ARG A N   
1141 C CA  . ARG A 136 ? 0.33831 0.25453 0.37125 0.00512  -0.05600 0.03180  136 ARG A CA  
1142 C C   . ARG A 136 ? 0.38055 0.33403 0.39332 -0.04617 -0.02473 -0.00049 136 ARG A C   
1143 O O   . ARG A 136 ? 0.42360 0.30492 0.37467 0.02079  -0.01457 0.03428  136 ARG A O   
1144 C CB  . ARG A 136 ? 0.31576 0.20781 0.43764 0.02851  -0.02166 0.00154  136 ARG A CB  
1145 C CG  . ARG A 136 ? 0.51416 0.25104 0.41077 0.04056  0.05164  -0.04238 136 ARG A CG  
1146 C CD  . ARG A 136 ? 0.59642 0.32070 0.43293 -0.02645 0.09939  -0.05371 136 ARG A CD  
1147 N NE  . ARG A 136 ? 0.61820 0.44407 0.44557 0.05871  0.04157  -0.04768 136 ARG A NE  
1148 C CZ  . ARG A 136 ? 0.54335 0.43996 0.46158 0.16899  0.04330  -0.07234 136 ARG A CZ  
1149 N NH1 . ARG A 136 ? 0.57827 0.45282 0.43216 0.12768  -0.00566 -0.05259 136 ARG A NH1 
1150 N NH2 . ARG A 136 ? 0.61056 0.43071 0.51054 0.23049  0.00151  -0.00286 136 ARG A NH2 
1151 N N   . GLY A 137 ? 0.40316 0.31455 0.38360 -0.01889 -0.02693 -0.03579 137 GLY A N   
1152 C CA  . GLY A 137 ? 0.32622 0.32694 0.38995 -0.04087 -0.02202 0.01612  137 GLY A CA  
1153 C C   . GLY A 137 ? 0.40320 0.32357 0.38023 0.01952  0.00858  0.00396  137 GLY A C   
1154 O O   . GLY A 137 ? 0.34350 0.37164 0.38103 0.00600  -0.02416 -0.03015 137 GLY A O   
1155 N N   A LEU A 138 ? 0.37849 0.33708 0.37890 0.03158  0.00552  0.02517  138 LEU A N   
1156 N N   B LEU A 138 ? 0.35271 0.36010 0.37999 0.03889  0.00069  0.02440  138 LEU A N   
1157 C CA  A LEU A 138 ? 0.37585 0.33977 0.38057 0.01315  -0.00175 0.02745  138 LEU A CA  
1158 C CA  B LEU A 138 ? 0.33840 0.35868 0.39078 0.00692  -0.00761 0.03131  138 LEU A CA  
1159 C C   A LEU A 138 ? 0.38537 0.34366 0.37279 0.01188  -0.01160 0.02545  138 LEU A C   
1160 C C   B LEU A 138 ? 0.35430 0.36503 0.38589 0.00038  0.01777  0.00713  138 LEU A C   
1161 O O   A LEU A 138 ? 0.43308 0.34281 0.37615 0.00379  -0.04043 0.06139  138 LEU A O   
1162 O O   B LEU A 138 ? 0.34086 0.35784 0.38983 -0.03058 0.00721  0.06336  138 LEU A O   
1163 C CB  A LEU A 138 ? 0.39048 0.32344 0.38917 0.02235  -0.04667 0.00421  138 LEU A CB  
1164 C CB  B LEU A 138 ? 0.33461 0.33136 0.39811 0.03971  -0.07534 0.03612  138 LEU A CB  
1165 C CG  A LEU A 138 ? 0.41495 0.34387 0.37856 -0.01469 -0.07412 -0.04455 138 LEU A CG  
1166 C CG  B LEU A 138 ? 0.27370 0.38976 0.36928 -0.00862 -0.06742 -0.00595 138 LEU A CG  
1167 C CD1 A LEU A 138 ? 0.40432 0.37565 0.37041 0.01076  -0.08499 -0.03473 138 LEU A CD1 
1168 C CD1 B LEU A 138 ? 0.30496 0.35306 0.37793 0.05982  -0.04412 -0.01643 138 LEU A CD1 
1169 C CD2 A LEU A 138 ? 0.38515 0.35663 0.35629 -0.02810 -0.13356 -0.07836 138 LEU A CD2 
1170 C CD2 B LEU A 138 ? 0.32725 0.41370 0.34248 -0.01706 -0.05251 -0.01795 138 LEU A CD2 
1171 N N   . LYS A 139 ? 0.35767 0.34153 0.34987 0.05322  0.01007  0.01740  139 LYS A N   
1172 C CA  . LYS A 139 ? 0.33026 0.37024 0.38155 0.03093  -0.05259 -0.01717 139 LYS A CA  
1173 C C   . LYS A 139 ? 0.33296 0.33647 0.41529 0.02584  -0.06722 0.05747  139 LYS A C   
1174 O O   . LYS A 139 ? 0.32874 0.38410 0.43056 -0.02526 -0.00870 -0.01471 139 LYS A O   
1175 C CB  . LYS A 139 ? 0.33552 0.41981 0.34678 0.03407  0.03940  -0.00787 139 LYS A CB  
1176 C CG  . LYS A 139 ? 0.31033 0.46096 0.38650 0.09339  0.03224  -0.02624 139 LYS A CG  
1177 C CD  . LYS A 139 ? 0.41330 0.45360 0.36226 0.06514  0.03459  -0.08279 139 LYS A CD  
1178 C CE  . LYS A 139 ? 0.46268 0.50913 0.37313 0.10060  -0.01165 -0.08691 139 LYS A CE  
1179 N NZ  . LYS A 139 ? 0.47048 0.50133 0.39917 0.08906  0.06420  -0.05124 139 LYS A NZ  
1180 N N   . TYR A 140 ? 0.31895 0.33609 0.36611 0.00199  -0.04738 0.09464  140 TYR A N   
1181 C CA  . TYR A 140 ? 0.31814 0.32497 0.36986 -0.04031 -0.09570 0.06656  140 TYR A CA  
1182 C C   . TYR A 140 ? 0.18591 0.33527 0.37793 -0.03224 -0.03331 0.04864  140 TYR A C   
1183 O O   . TYR A 140 ? 0.28059 0.33360 0.43575 -0.03694 -0.03158 0.08310  140 TYR A O   
1184 C CB  . TYR A 140 ? 0.31006 0.36248 0.36615 0.06551  -0.03300 0.04991  140 TYR A CB  
1185 C CG  . TYR A 140 ? 0.33217 0.31446 0.37531 0.09219  0.00341  0.03485  140 TYR A CG  
1186 C CD1 . TYR A 140 ? 0.25894 0.28016 0.39309 0.05377  -0.00224 0.06032  140 TYR A CD1 
1187 C CD2 . TYR A 140 ? 0.40712 0.29850 0.34298 0.01185  -0.05194 0.05289  140 TYR A CD2 
1188 C CE1 . TYR A 140 ? 0.32042 0.32349 0.36654 0.04267  0.00971  0.01401  140 TYR A CE1 
1189 C CE2 . TYR A 140 ? 0.44923 0.36620 0.37237 -0.00202 -0.00404 0.04547  140 TYR A CE2 
1190 C CZ  . TYR A 140 ? 0.30460 0.40026 0.36685 0.05329  -0.03371 0.01305  140 TYR A CZ  
1191 O OH  . TYR A 140 ? 0.28034 0.43031 0.37889 0.02330  -0.04083 0.01277  140 TYR A OH  
1192 N N   . ILE A 141 ? 0.29958 0.35259 0.37727 0.04276  0.03848  0.02659  141 ILE A N   
1193 C CA  . ILE A 141 ? 0.45997 0.35719 0.40086 -0.02903 0.03339  0.09100  141 ILE A CA  
1194 C C   . ILE A 141 ? 0.39763 0.36770 0.43117 -0.07200 -0.02552 0.06210  141 ILE A C   
1195 O O   . ILE A 141 ? 0.33765 0.38292 0.43674 -0.04284 -0.02634 0.07161  141 ILE A O   
1196 C CB  . ILE A 141 ? 0.63439 0.34870 0.39204 -0.18043 0.09744  0.08761  141 ILE A CB  
1197 C CG1 . ILE A 141 ? 0.70592 0.37104 0.41705 -0.16380 0.10095  0.06461  141 ILE A CG1 
1198 C CG2 . ILE A 141 ? 0.68566 0.44185 0.43641 0.02742  0.04552  0.08587  141 ILE A CG2 
1199 C CD1 . ILE A 141 ? 0.90068 0.40908 0.44937 -0.14141 0.02312  0.08224  141 ILE A CD1 
1200 N N   . HIS A 142 ? 0.27301 0.39727 0.40850 0.03829  -0.05869 0.03790  142 HIS A N   
1201 C CA  . HIS A 142 ? 0.33031 0.37266 0.42309 0.06164  -0.00810 0.05262  142 HIS A CA  
1202 C C   . HIS A 142 ? 0.28326 0.40270 0.44590 -0.01140 -0.00225 0.08710  142 HIS A C   
1203 O O   . HIS A 142 ? 0.33829 0.42055 0.44096 -0.05698 -0.01831 0.08852  142 HIS A O   
1204 C CB  . HIS A 142 ? 0.17930 0.34260 0.39516 0.07674  -0.00636 0.07293  142 HIS A CB  
1205 C CG  . HIS A 142 ? 0.18499 0.32439 0.38998 0.04317  0.03400  0.04271  142 HIS A CG  
1206 N ND1 . HIS A 142 ? 0.24809 0.40527 0.40681 0.05559  0.02838  -0.01390 142 HIS A ND1 
1207 C CD2 . HIS A 142 ? 0.30274 0.31327 0.38596 0.07393  0.02099  0.00290  142 HIS A CD2 
1208 C CE1 . HIS A 142 ? 0.28984 0.44705 0.34381 0.04324  0.06827  -0.03428 142 HIS A CE1 
1209 N NE2 . HIS A 142 ? 0.41003 0.37188 0.34371 0.00219  -0.05159 -0.00267 142 HIS A NE2 
1210 N N   . SER A 143 ? 0.24376 0.45290 0.48035 0.05614  -0.01437 0.06344  143 SER A N   
1211 C CA  . SER A 143 ? 0.20953 0.40708 0.54181 0.05307  0.04876  0.06591  143 SER A CA  
1212 C C   . SER A 143 ? 0.39989 0.44573 0.60458 0.03051  0.04284  0.04258  143 SER A C   
1213 O O   . SER A 143 ? 0.36450 0.47086 0.65471 0.01353  0.03257  0.09238  143 SER A O   
1214 C CB  . SER A 143 ? 0.36571 0.38187 0.52717 0.07696  -0.00002 0.12795  143 SER A CB  
1215 O OG  . SER A 143 ? 0.32660 0.35952 0.52855 0.02143  0.03092  0.10409  143 SER A OG  
1216 N N   . ALA A 144 ? 0.30285 0.41666 0.61323 -0.01349 -0.06417 0.00704  144 ALA A N   
1217 C CA  . ALA A 144 ? 0.41843 0.38288 0.60396 -0.06241 -0.12427 0.03429  144 ALA A CA  
1218 C C   . ALA A 144 ? 0.31128 0.41289 0.61645 -0.09669 -0.09232 0.04705  144 ALA A C   
1219 O O   . ALA A 144 ? 0.27141 0.47289 0.63677 0.00663  -0.10965 -0.00468 144 ALA A O   
1220 C CB  . ALA A 144 ? 0.48258 0.33762 0.62670 0.02659  -0.20413 0.00559  144 ALA A CB  
1221 N N   . ASP A 145 ? 0.25140 0.46662 0.58605 0.01257  -0.01095 0.10472  145 ASP A N   
1222 C CA  . ASP A 145 ? 0.43261 0.47926 0.58326 0.00421  0.09070  0.13194  145 ASP A CA  
1223 C C   . ASP A 145 ? 0.40980 0.47166 0.53349 -0.02325 -0.00839 0.08533  145 ASP A C   
1224 O O   . ASP A 145 ? 0.39550 0.42293 0.57065 -0.02914 -0.05809 0.06558  145 ASP A O   
1225 C CB  . ASP A 145 ? 0.49055 0.60094 0.62221 -0.07608 0.13221  0.17371  145 ASP A CB  
1226 C CG  . ASP A 145 ? 0.91376 0.81716 0.75724 -0.09989 0.05716  0.20941  145 ASP A CG  
1227 O OD1 . ASP A 145 ? 1.07098 0.96973 0.82776 -0.02726 -0.00953 0.21930  145 ASP A OD1 
1228 O OD2 . ASP A 145 ? 1.10545 0.84437 0.78284 -0.09685 0.06694  0.27465  145 ASP A OD2 
1229 N N   . ILE A 146 ? 0.30863 0.50539 0.47347 -0.01251 0.01752  0.10150  146 ILE A N   
1230 C CA  . ILE A 146 ? 0.34797 0.55475 0.46606 -0.01554 -0.03878 0.05898  146 ILE A CA  
1231 C C   . ILE A 146 ? 0.32685 0.56976 0.47262 -0.00952 -0.00560 0.00814  146 ILE A C   
1232 O O   . ILE A 146 ? 0.33047 0.59804 0.51356 0.01027  -0.02895 -0.05014 146 ILE A O   
1233 C CB  . ILE A 146 ? 0.26020 0.64030 0.49098 -0.05153 -0.05090 0.09164  146 ILE A CB  
1234 C CG1 . ILE A 146 ? 0.34151 0.59115 0.51729 -0.03958 -0.07553 0.13581  146 ILE A CG1 
1235 C CG2 . ILE A 146 ? 0.36704 0.68018 0.53090 -0.06470 -0.01054 0.09029  146 ILE A CG2 
1236 C CD1 . ILE A 146 ? 0.35097 0.60715 0.53088 -0.00113 -0.04161 0.11675  146 ILE A CD1 
1237 N N   . ILE A 147 ? 0.32037 0.51130 0.41083 -0.08346 0.01512  0.06143  147 ILE A N   
1238 C CA  . ILE A 147 ? 0.29104 0.48517 0.40733 -0.06095 0.04747  0.03426  147 ILE A CA  
1239 C C   . ILE A 147 ? 0.38759 0.44477 0.39290 -0.11378 -0.00280 0.02569  147 ILE A C   
1240 O O   . ILE A 147 ? 0.44827 0.48614 0.40435 -0.08596 -0.02664 -0.01027 147 ILE A O   
1241 C CB  . ILE A 147 ? 0.33932 0.52286 0.42354 -0.05796 0.03003  0.08348  147 ILE A CB  
1242 C CG1 . ILE A 147 ? 0.30429 0.54909 0.46874 -0.06486 0.05123  0.15686  147 ILE A CG1 
1243 C CG2 . ILE A 147 ? 0.42672 0.56576 0.40999 -0.06427 0.06704  0.08244  147 ILE A CG2 
1244 C CD1 . ILE A 147 ? 0.48832 0.47788 0.50427 -0.08249 0.03079  0.15344  147 ILE A CD1 
1245 N N   . HIS A 148 ? 0.35786 0.43101 0.40544 -0.04335 0.00798  0.01076  148 HIS A N   
1246 C CA  . HIS A 148 ? 0.29241 0.42994 0.39823 -0.10500 0.04534  0.00887  148 HIS A CA  
1247 C C   . HIS A 148 ? 0.38029 0.45472 0.39137 -0.03614 -0.01578 -0.05070 148 HIS A C   
1248 O O   . HIS A 148 ? 0.35979 0.45170 0.30436 -0.03560 -0.04673 -0.00441 148 HIS A O   
1249 C CB  . HIS A 148 ? 0.35272 0.42762 0.38098 -0.06998 0.01402  -0.00074 148 HIS A CB  
1250 C CG  . HIS A 148 ? 0.31128 0.49407 0.33327 0.01955  -0.00724 0.00557  148 HIS A CG  
1251 N ND1 . HIS A 148 ? 0.32452 0.53085 0.30240 -0.02021 0.03995  0.00891  148 HIS A ND1 
1252 C CD2 . HIS A 148 ? 0.37763 0.45680 0.31728 0.03965  -0.05444 0.01507  148 HIS A CD2 
1253 C CE1 . HIS A 148 ? 0.38743 0.54928 0.35742 -0.02420 0.00654  0.02450  148 HIS A CE1 
1254 N NE2 . HIS A 148 ? 0.39296 0.50014 0.38526 -0.01906 -0.00014 0.00920  148 HIS A NE2 
1255 N N   . ARG A 149 ? 0.35755 0.44153 0.40040 -0.07174 0.01282  -0.05984 149 ARG A N   
1256 C CA  . ARG A 149 ? 0.36818 0.42082 0.46617 -0.15488 0.02209  -0.01111 149 ARG A CA  
1257 C C   . ARG A 149 ? 0.32548 0.47215 0.45478 -0.03669 -0.00452 0.01040  149 ARG A C   
1258 O O   . ARG A 149 ? 0.49492 0.49289 0.49651 0.04995  -0.00290 -0.02765 149 ARG A O   
1259 C CB  . ARG A 149 ? 0.32657 0.52229 0.52815 -0.13870 -0.02558 -0.04830 149 ARG A CB  
1260 C CG  . ARG A 149 ? 0.60274 0.60336 0.63621 -0.19786 -0.02443 -0.04227 149 ARG A CG  
1261 C CD  . ARG A 149 ? 0.65691 0.71606 0.73323 -0.14121 -0.00665 -0.01355 149 ARG A CD  
1262 N NE  . ARG A 149 ? 0.64962 0.76817 0.80962 -0.03145 -0.11227 0.02116  149 ARG A NE  
1263 C CZ  . ARG A 149 ? 0.83840 0.81126 0.86908 -0.07600 -0.12962 0.06208  149 ARG A CZ  
1264 N NH1 . ARG A 149 ? 0.95882 0.82288 0.89590 -0.08912 -0.13967 0.05432  149 ARG A NH1 
1265 N NH2 . ARG A 149 ? 0.90475 0.80625 0.87800 -0.12139 -0.08627 0.11184  149 ARG A NH2 
1266 N N   . ASP A 150 ? 0.33499 0.50692 0.36820 -0.08786 0.01496  0.00188  150 ASP A N   
1267 C CA  . ASP A 150 ? 0.37555 0.50023 0.37039 -0.01570 0.01615  -0.00732 150 ASP A CA  
1268 C C   . ASP A 150 ? 0.33997 0.49102 0.32486 -0.00179 -0.00576 -0.02484 150 ASP A C   
1269 O O   . ASP A 150 ? 0.44006 0.51028 0.32354 -0.05658 0.00172  -0.04414 150 ASP A O   
1270 C CB  . ASP A 150 ? 0.55668 0.56655 0.41284 -0.00690 0.04499  -0.04634 150 ASP A CB  
1271 C CG  . ASP A 150 ? 0.77114 0.59285 0.43752 -0.05070 -0.01715 -0.04457 150 ASP A CG  
1272 O OD1 . ASP A 150 ? 0.82358 0.57066 0.49953 0.09549  -0.10798 -0.05686 150 ASP A OD1 
1273 O OD2 . ASP A 150 ? 0.74963 0.64044 0.41835 -0.16816 0.10432  -0.03152 150 ASP A OD2 
1274 N N   A LEU A 151 ? 0.37546 0.40281 0.29385 0.02426  0.02773  -0.02325 151 LEU A N   
1275 N N   B LEU A 151 ? 0.36502 0.39134 0.30129 0.02763  0.02634  -0.00683 151 LEU A N   
1276 C CA  A LEU A 151 ? 0.39073 0.41679 0.30417 -0.00697 0.02003  -0.00421 151 LEU A CA  
1277 C CA  B LEU A 151 ? 0.40128 0.38348 0.31593 -0.01107 0.02451  0.01737  151 LEU A CA  
1278 C C   A LEU A 151 ? 0.36814 0.37624 0.30359 -0.01394 -0.00343 -0.02656 151 LEU A C   
1279 C C   B LEU A 151 ? 0.35716 0.36133 0.33635 -0.01921 0.00411  0.03797  151 LEU A C   
1280 O O   A LEU A 151 ? 0.37139 0.34889 0.32952 0.02217  -0.01608 -0.04247 151 LEU A O   
1281 O O   B LEU A 151 ? 0.32710 0.34737 0.37140 0.03026  0.00227  0.05008  151 LEU A O   
1282 C CB  A LEU A 151 ? 0.36954 0.43429 0.33895 0.05904  0.05023  0.01128  151 LEU A CB  
1283 C CB  B LEU A 151 ? 0.42636 0.35787 0.34437 0.03411  0.04927  -0.00494 151 LEU A CB  
1284 C CG  A LEU A 151 ? 0.42061 0.41569 0.36014 0.00073  -0.01938 0.04582  151 LEU A CG  
1285 C CG  B LEU A 151 ? 0.46337 0.27357 0.36018 0.00848  -0.01171 -0.01311 151 LEU A CG  
1286 C CD1 A LEU A 151 ? 0.50059 0.43539 0.38787 0.06990  -0.08176 0.05360  151 LEU A CD1 
1287 C CD1 B LEU A 151 ? 0.33570 0.22942 0.35922 -0.08526 -0.00554 -0.05844 151 LEU A CD1 
1288 C CD2 A LEU A 151 ? 0.40651 0.44559 0.34284 -0.06069 -0.02854 0.08115  151 LEU A CD2 
1289 C CD2 B LEU A 151 ? 0.42286 0.28825 0.39200 0.10136  0.00342  -0.00819 151 LEU A CD2 
1290 N N   A LYS A 152 ? 0.37883 0.38868 0.31615 -0.06528 0.05542  -0.03580 152 LYS A N   
1291 N N   B LYS A 152 ? 0.36686 0.36436 0.35843 -0.07595 0.05712  0.01532  152 LYS A N   
1292 C CA  A LYS A 152 ? 0.30762 0.39564 0.35412 -0.07124 0.06689  -0.04031 152 LYS A CA  
1293 C CA  B LYS A 152 ? 0.30399 0.37778 0.40896 -0.08493 0.06113  -0.02525 152 LYS A CA  
1294 C C   A LYS A 152 ? 0.31707 0.34939 0.37011 -0.03347 0.04119  -0.01784 152 LYS A C   
1295 C C   B LYS A 152 ? 0.29577 0.35093 0.41993 -0.06151 0.03692  0.01479  152 LYS A C   
1296 O O   A LYS A 152 ? 0.40683 0.32538 0.35978 0.06317  0.00209  -0.03923 152 LYS A O   
1297 O O   B LYS A 152 ? 0.37299 0.37198 0.45160 -0.01448 -0.02102 0.03384  152 LYS A O   
1298 C CB  A LYS A 152 ? 0.35854 0.48092 0.38615 -0.00705 0.07920  -0.05578 152 LYS A CB  
1299 C CB  B LYS A 152 ? 0.39732 0.46200 0.44750 -0.02384 0.04689  -0.05240 152 LYS A CB  
1300 C CG  A LYS A 152 ? 0.33758 0.52806 0.40823 -0.00908 0.08489  -0.08076 152 LYS A CG  
1301 C CG  B LYS A 152 ? 0.46121 0.48108 0.48183 -0.06928 0.05517  -0.05788 152 LYS A CG  
1302 C CD  A LYS A 152 ? 0.46013 0.52610 0.38369 -0.00349 0.06201  -0.08481 152 LYS A CD  
1303 C CD  B LYS A 152 ? 0.38460 0.42971 0.47733 -0.06060 0.02648  -0.08147 152 LYS A CD  
1304 C CE  A LYS A 152 ? 0.36376 0.49211 0.35768 -0.01711 0.01005  -0.13086 152 LYS A CE  
1305 C CE  B LYS A 152 ? 0.48009 0.39765 0.46558 -0.08707 -0.07656 -0.09709 152 LYS A CE  
1306 N NZ  A LYS A 152 ? 0.38664 0.53819 0.31850 -0.02300 -0.00167 -0.09758 152 LYS A NZ  
1307 N NZ  B LYS A 152 ? 0.53309 0.39960 0.43662 0.01639  -0.14525 -0.10318 152 LYS A NZ  
1308 N N   . PRO A 153 ? 0.32297 0.36073 0.39109 0.01001  0.02363  -0.00679 153 PRO A N   
1309 C CA  . PRO A 153 ? 0.39556 0.31450 0.37653 -0.02152 0.00655  0.05384  153 PRO A CA  
1310 C C   . PRO A 153 ? 0.36625 0.33159 0.37849 -0.00760 -0.00556 0.07511  153 PRO A C   
1311 O O   . PRO A 153 ? 0.44641 0.33206 0.40634 0.06199  0.02252  0.06765  153 PRO A O   
1312 C CB  . PRO A 153 ? 0.38007 0.36285 0.39611 -0.02570 -0.00287 0.08285  153 PRO A CB  
1313 C CG  . PRO A 153 ? 0.27458 0.37033 0.42430 -0.01140 -0.00738 0.08620  153 PRO A CG  
1314 C CD  . PRO A 153 ? 0.27331 0.40300 0.41320 -0.04168 0.00254  0.00963  153 PRO A CD  
1315 N N   . SER A 154 ? 0.38476 0.38078 0.35285 0.01405  -0.00326 -0.02380 154 SER A N   
1316 C CA  . SER A 154 ? 0.43686 0.42846 0.37015 0.03745  0.00646  0.02918  154 SER A CA  
1317 C C   . SER A 154 ? 0.36866 0.44726 0.36713 0.00751  -0.00953 0.05886  154 SER A C   
1318 O O   . SER A 154 ? 0.45700 0.50594 0.39391 0.07331  -0.02927 0.06006  154 SER A O   
1319 C CB  . SER A 154 ? 0.54996 0.43335 0.37126 0.03046  -0.01022 0.01932  154 SER A CB  
1320 O OG  . SER A 154 ? 0.43276 0.47079 0.42723 0.02687  -0.02100 0.01917  154 SER A OG  
1321 N N   A ASN A 155 ? 0.34435 0.49026 0.39569 -0.01701 0.06253  0.01791  155 ASN A N   
1322 N N   B ASN A 155 ? 0.39758 0.43872 0.38083 -0.00581 0.00869  0.04853  155 ASN A N   
1323 C CA  A ASN A 155 ? 0.43471 0.45445 0.44001 -0.03482 0.07617  -0.01213 155 ASN A CA  
1324 C CA  B ASN A 155 ? 0.42432 0.42035 0.39453 -0.03682 0.02501  0.04384  155 ASN A CA  
1325 C C   A ASN A 155 ? 0.46902 0.36540 0.41641 0.02225  0.00320  0.01148  155 ASN A C   
1326 C C   B ASN A 155 ? 0.40415 0.39319 0.38262 -0.00865 -0.01089 0.04101  155 ASN A C   
1327 O O   A ASN A 155 ? 0.37231 0.38550 0.41511 0.03705  -0.04862 0.02645  155 ASN A O   
1328 O O   B ASN A 155 ? 0.39578 0.39701 0.37788 -0.00135 -0.02708 0.02605  155 ASN A O   
1329 C CB  A ASN A 155 ? 0.38214 0.45271 0.51578 -0.02442 0.06831  -0.09720 155 ASN A CB  
1330 C CB  B ASN A 155 ? 0.44561 0.43013 0.41546 -0.07410 0.03099  0.04653  155 ASN A CB  
1331 C CG  A ASN A 155 ? 0.52958 0.46679 0.54806 0.00951  0.06543  -0.05930 155 ASN A CG  
1332 C CG  B ASN A 155 ? 0.41643 0.42317 0.41737 -0.12143 0.03082  0.10420  155 ASN A CG  
1333 O OD1 A ASN A 155 ? 0.55135 0.52132 0.57511 -0.01746 0.03268  -0.06927 155 ASN A OD1 
1334 O OD1 B ASN A 155 ? 0.52479 0.48677 0.43941 -0.18435 0.07688  0.11060  155 ASN A OD1 
1335 N ND2 A ASN A 155 ? 0.47585 0.41765 0.52126 -0.03812 0.17929  0.05066  155 ASN A ND2 
1336 N ND2 B ASN A 155 ? 0.37715 0.35072 0.41714 -0.13682 0.04040  0.10526  155 ASN A ND2 
1337 N N   . LEU A 156 ? 0.38225 0.38404 0.38055 -0.02776 -0.03164 0.04015  156 LEU A N   
1338 C CA  . LEU A 156 ? 0.36716 0.38708 0.42002 -0.06917 -0.02296 0.02236  156 LEU A CA  
1339 C C   . LEU A 156 ? 0.38244 0.39809 0.48104 -0.00657 -0.01617 0.05400  156 LEU A C   
1340 O O   . LEU A 156 ? 0.42930 0.44794 0.54364 0.00873  0.04594  0.05040  156 LEU A O   
1341 C CB  . LEU A 156 ? 0.37328 0.35752 0.39342 0.02674  -0.03311 0.02331  156 LEU A CB  
1342 C CG  . LEU A 156 ? 0.39079 0.38669 0.42328 0.08418  -0.03583 0.05727  156 LEU A CG  
1343 C CD1 . LEU A 156 ? 0.45610 0.37908 0.42900 0.00717  0.03324  0.05943  156 LEU A CD1 
1344 C CD2 . LEU A 156 ? 0.32896 0.42093 0.44839 0.03207  -0.02711 0.04030  156 LEU A CD2 
1345 N N   . ALA A 157 ? 0.36662 0.32103 0.46311 0.04578  0.02507  0.06167  157 ALA A N   
1346 C CA  . ALA A 157 ? 0.52383 0.37258 0.47542 0.00698  -0.02008 0.08361  157 ALA A CA  
1347 C C   . ALA A 157 ? 0.44869 0.39263 0.48230 -0.02847 0.03686  0.10571  157 ALA A C   
1348 O O   . ALA A 157 ? 0.47599 0.41307 0.48911 -0.01554 0.07990  0.13560  157 ALA A O   
1349 C CB  . ALA A 157 ? 0.58617 0.37875 0.46953 0.03449  -0.06457 0.06391  157 ALA A CB  
1350 N N   . VAL A 158 ? 0.51120 0.43989 0.50281 -0.03960 0.03000  0.07087  158 VAL A N   
1351 C CA  . VAL A 158 ? 0.60809 0.47969 0.55357 -0.07962 0.06071  0.11638  158 VAL A CA  
1352 C C   . VAL A 158 ? 0.74002 0.53076 0.57241 -0.10753 0.12855  0.09447  158 VAL A C   
1353 O O   . VAL A 158 ? 0.74638 0.59012 0.56296 -0.14764 0.17536  0.05020  158 VAL A O   
1354 C CB  . VAL A 158 ? 0.60943 0.46302 0.56140 -0.06973 0.06374  0.11057  158 VAL A CB  
1355 C CG1 . VAL A 158 ? 0.75576 0.48051 0.55178 0.00241  0.07468  0.10325  158 VAL A CG1 
1356 C CG2 . VAL A 158 ? 0.55070 0.49078 0.54706 -0.04771 0.04591  0.13067  158 VAL A CG2 
1357 N N   . ASN A 159 ? 0.85711 0.48723 0.59206 -0.07576 0.15995  0.14302  159 ASN A N   
1358 C CA  . ASN A 159 ? 0.78420 0.50371 0.66174 -0.07989 0.17503  0.12353  159 ASN A CA  
1359 C C   . ASN A 159 ? 0.97864 0.50230 0.71930 -0.09456 0.25917  0.14458  159 ASN A C   
1360 O O   . ASN A 159 ? 0.89140 0.45430 0.69045 -0.10282 0.27334  0.10372  159 ASN A O   
1361 C CB  . ASN A 159 ? 0.76341 0.47585 0.64485 -0.03929 0.13174  0.11780  159 ASN A CB  
1362 C CG  . ASN A 159 ? 0.78530 0.45859 0.66212 0.01008  0.11647  0.09107  159 ASN A CG  
1363 O OD1 . ASN A 159 ? 0.88732 0.44484 0.65870 -0.08300 0.18365  0.07270  159 ASN A OD1 
1364 N ND2 . ASN A 159 ? 0.78199 0.52338 0.67687 0.00709  0.11791  0.06228  159 ASN A ND2 
1365 N N   . GLU A 160 ? 1.06585 0.60835 0.79846 -0.16591 0.26737  0.19058  160 GLU A N   
1366 C CA  . GLU A 160 ? 1.02675 0.74247 0.88241 -0.13923 0.24260  0.20964  160 GLU A CA  
1367 C C   . GLU A 160 ? 0.88133 0.72403 0.90805 -0.16051 0.20739  0.24369  160 GLU A C   
1368 O O   . GLU A 160 ? 0.86460 0.72501 0.93326 -0.10388 0.20420  0.25137  160 GLU A O   
1369 C CB  . GLU A 160 ? 1.11717 0.84252 0.93384 -0.15766 0.29650  0.25161  160 GLU A CB  
1370 C CG  . GLU A 160 ? 1.28936 0.97166 1.01929 -0.12451 0.23909  0.25706  160 GLU A CG  
1371 C CD  . GLU A 160 ? 1.34851 1.07313 1.08085 -0.15133 0.25317  0.27199  160 GLU A CD  
1372 O OE1 . GLU A 160 ? 1.33554 1.12960 1.11807 -0.13315 0.25211  0.27740  160 GLU A OE1 
1373 O OE2 . GLU A 160 ? 1.39203 1.09906 1.08617 -0.16752 0.24378  0.27022  160 GLU A OE2 
1374 N N   . ASP A 161 ? 0.78750 0.69896 0.87346 -0.18048 0.22971  0.26442  161 ASP A N   
1375 C CA  . ASP A 161 ? 0.79670 0.67298 0.87200 -0.17412 0.14915  0.25865  161 ASP A CA  
1376 C C   . ASP A 161 ? 0.66152 0.67141 0.85567 -0.18673 0.13829  0.21319  161 ASP A C   
1377 O O   . ASP A 161 ? 0.67492 0.71919 0.87181 -0.22248 0.09097  0.19612  161 ASP A O   
1378 C CB  . ASP A 161 ? 0.83278 0.67477 0.89956 -0.03995 0.09377  0.30758  161 ASP A CB  
1379 C CG  . ASP A 161 ? 0.92822 0.76109 0.95886 0.01848  0.07517  0.29313  161 ASP A CG  
1380 O OD1 . ASP A 161 ? 0.87747 0.75829 0.98047 -0.01481 0.12921  0.29521  161 ASP A OD1 
1381 O OD2 . ASP A 161 ? 0.99423 0.74572 0.97140 0.14275  -0.00502 0.32509  161 ASP A OD2 
1382 N N   . CYS A 162 ? 0.63152 0.59465 0.82768 -0.09393 0.13010  0.14275  162 CYS A N   
1383 C CA  . CYS A 162 ? 0.53063 0.54829 0.78875 -0.12590 0.17569  0.08179  162 CYS A CA  
1384 C C   . CYS A 162 ? 0.52111 0.41426 0.69591 -0.03871 0.14363  0.06918  162 CYS A C   
1385 O O   . CYS A 162 ? 0.49585 0.35044 0.67514 -0.01161 0.12115  0.06604  162 CYS A O   
1386 C CB  . CYS A 162 ? 0.54531 0.74073 0.83555 -0.20683 0.22764  0.03097  162 CYS A CB  
1387 S SG  . CYS A 162 ? 0.79848 0.96111 0.91430 -0.14457 0.00847  0.07468  162 CYS A SG  
1388 N N   . GLU A 163 ? 0.55503 0.36291 0.63688 0.01015  0.12572  0.03617  163 GLU A N   
1389 C CA  . GLU A 163 ? 0.56514 0.33627 0.57490 -0.00141 0.02335  0.00243  163 GLU A CA  
1390 C C   . GLU A 163 ? 0.51350 0.35285 0.53460 -0.06620 -0.01315 -0.01526 163 GLU A C   
1391 O O   . GLU A 163 ? 0.61956 0.42301 0.52792 -0.03802 0.01250  0.01194  163 GLU A O   
1392 C CB  . GLU A 163 ? 0.67069 0.40795 0.58354 0.01665  -0.01210 -0.00370 163 GLU A CB  
1393 C CG  . GLU A 163 ? 0.69636 0.46916 0.63853 0.04808  -0.02508 -0.00133 163 GLU A CG  
1394 C CD  . GLU A 163 ? 0.82491 0.53723 0.68064 0.07326  -0.00899 0.01099  163 GLU A CD  
1395 O OE1 . GLU A 163 ? 0.85694 0.52886 0.68212 0.06565  -0.02740 0.07288  163 GLU A OE1 
1396 O OE2 . GLU A 163 ? 0.95883 0.61024 0.72727 0.14700  0.02990  0.00466  163 GLU A OE2 
1397 N N   . LEU A 164 ? 0.47207 0.32877 0.49631 -0.02575 0.00144  -0.00431 164 LEU A N   
1398 C CA  . LEU A 164 ? 0.38625 0.28713 0.48004 -0.03869 0.04849  -0.00468 164 LEU A CA  
1399 C C   . LEU A 164 ? 0.53454 0.30046 0.46593 0.00637  -0.05597 0.00791  164 LEU A C   
1400 O O   . LEU A 164 ? 0.51590 0.31981 0.45476 -0.01302 -0.04987 -0.01584 164 LEU A O   
1401 C CB  . LEU A 164 ? 0.37525 0.32072 0.46333 -0.03094 0.01165  0.01284  164 LEU A CB  
1402 C CG  . LEU A 164 ? 0.30860 0.33199 0.45720 0.00732  0.03473  0.04064  164 LEU A CG  
1403 C CD1 . LEU A 164 ? 0.31798 0.36626 0.45194 0.04198  0.03829  0.03067  164 LEU A CD1 
1404 C CD2 . LEU A 164 ? 0.26497 0.33828 0.44470 0.04387  -0.00725 0.03511  164 LEU A CD2 
1405 N N   . LYS A 165 ? 0.45841 0.33329 0.40365 0.07145  -0.05263 -0.01605 165 LYS A N   
1406 C CA  . LYS A 165 ? 0.43395 0.32709 0.42232 0.00842  -0.03242 -0.00950 165 LYS A CA  
1407 C C   . LYS A 165 ? 0.42223 0.36884 0.40313 0.00245  0.00810  0.00261  165 LYS A C   
1408 O O   . LYS A 165 ? 0.43607 0.43782 0.40042 0.01479  0.01347  0.00983  165 LYS A O   
1409 C CB  . LYS A 165 ? 0.44248 0.45878 0.47201 0.02636  -0.04110 0.00477  165 LYS A CB  
1410 C CG  . LYS A 165 ? 0.41248 0.54633 0.51342 0.04241  -0.02249 0.00111  165 LYS A CG  
1411 C CD  . LYS A 165 ? 0.50436 0.56943 0.56377 -0.04234 0.04743  0.02581  165 LYS A CD  
1412 C CE  . LYS A 165 ? 0.61091 0.59864 0.63046 -0.07066 0.14423  0.00995  165 LYS A CE  
1413 N NZ  . LYS A 165 ? 0.65595 0.55056 0.68309 -0.01072 0.17121  0.05495  165 LYS A NZ  
1414 N N   . ILE A 166 ? 0.36649 0.33787 0.33606 -0.01440 -0.03630 0.00829  166 ILE A N   
1415 C CA  . ILE A 166 ? 0.40502 0.24658 0.34056 0.00936  -0.07316 0.03333  166 ILE A CA  
1416 C C   . ILE A 166 ? 0.35753 0.34416 0.36224 0.05772  -0.05260 0.01935  166 ILE A C   
1417 O O   . ILE A 166 ? 0.46676 0.36818 0.40523 0.04048  -0.01642 0.06401  166 ILE A O   
1418 C CB  . ILE A 166 ? 0.32049 0.29341 0.33841 0.02765  -0.02243 0.03934  166 ILE A CB  
1419 C CG1 . ILE A 166 ? 0.32004 0.34729 0.30268 -0.02541 0.01415  0.03666  166 ILE A CG1 
1420 C CG2 . ILE A 166 ? 0.38983 0.32956 0.40076 0.07622  0.03302  0.04135  166 ILE A CG2 
1421 C CD1 . ILE A 166 ? 0.39530 0.38075 0.27060 0.01505  0.07050  0.04054  166 ILE A CD1 
1422 N N   . LEU A 167 ? 0.36660 0.32761 0.39358 0.01443  0.04207  -0.01750 167 LEU A N   
1423 C CA  . LEU A 167 ? 0.40532 0.42179 0.39429 -0.02333 0.08671  -0.02222 167 LEU A CA  
1424 C C   . LEU A 167 ? 0.52825 0.49143 0.41886 -0.07154 0.03328  0.05253  167 LEU A C   
1425 O O   . LEU A 167 ? 0.53418 0.53307 0.40509 -0.09344 -0.02083 0.07154  167 LEU A O   
1426 C CB  . LEU A 167 ? 0.52735 0.48442 0.38375 -0.04746 0.02930  0.06525  167 LEU A CB  
1427 C CG  . LEU A 167 ? 0.64640 0.57780 0.41959 0.08156  0.10430  0.07939  167 LEU A CG  
1428 C CD1 . LEU A 167 ? 0.84586 0.63190 0.41923 0.03813  0.10666  0.05217  167 LEU A CD1 
1429 C CD2 . LEU A 167 ? 0.67763 0.59632 0.47948 0.21019  0.04514  0.03687  167 LEU A CD2 
1430 N N   A ASP A 168 ? 0.54480 0.51239 0.41949 -0.02365 -0.03235 0.01299  168 ASP A N   
1431 N N   B ASP A 168 ? 0.50150 0.50312 0.46273 -0.06459 -0.01200 0.03191  168 ASP A N   
1432 C CA  A ASP A 168 ? 0.54914 0.53922 0.42915 -0.00816 -0.00806 0.00246  168 ASP A CA  
1433 C CA  B ASP A 168 ? 0.48338 0.53023 0.50148 -0.12003 -0.01123 0.00963  168 ASP A CA  
1434 C C   A ASP A 168 ? 0.45287 0.54539 0.45972 -0.02373 -0.02165 -0.00773 168 ASP A C   
1435 C C   B ASP A 168 ? 0.48103 0.55606 0.51502 -0.12594 -0.01628 -0.03342 168 ASP A C   
1436 O O   A ASP A 168 ? 0.41456 0.55850 0.43769 -0.02165 0.03885  0.00907  168 ASP A O   
1437 O O   B ASP A 168 ? 0.52668 0.57037 0.48196 -0.14713 0.03566  -0.05895 168 ASP A O   
1438 C CB  A ASP A 168 ? 0.69172 0.60779 0.42927 0.04687  -0.00356 -0.00189 168 ASP A CB  
1439 C CB  B ASP A 168 ? 0.54684 0.55666 0.52253 -0.09605 -0.03401 0.01306  168 ASP A CB  
1440 C CG  A ASP A 168 ? 0.82483 0.69632 0.45550 0.10944  -0.01082 -0.00381 168 ASP A CG  
1441 C CG  B ASP A 168 ? 0.60200 0.59061 0.55018 -0.04620 0.00174  0.02591  168 ASP A CG  
1442 O OD1 A ASP A 168 ? 0.73931 0.72532 0.40003 0.18105  -0.07229 0.00616  168 ASP A OD1 
1443 O OD1 B ASP A 168 ? 0.63010 0.60266 0.57577 -0.06775 0.06186  0.02534  168 ASP A OD1 
1444 O OD2 A ASP A 168 ? 0.99350 0.72298 0.49703 0.11551  0.00724  -0.01709 168 ASP A OD2 
1445 O OD2 B ASP A 168 ? 0.65995 0.61158 0.56530 -0.01456 -0.05532 0.02363  168 ASP A OD2 
1446 N N   A PHE A 169 ? 0.46695 0.53720 0.51079 -0.03671 -0.03841 -0.01297 169 PHE A N   
1447 N N   B PHE A 169 ? 0.31194 0.55337 0.55501 -0.12184 -0.07152 -0.04790 169 PHE A N   
1448 C CA  A PHE A 169 ? 0.51793 0.52839 0.58245 0.03756  -0.00774 -0.06180 169 PHE A CA  
1449 C CA  B PHE A 169 ? 0.48759 0.55728 0.59180 -0.05493 -0.05081 -0.06113 169 PHE A CA  
1450 C C   A PHE A 169 ? 0.51961 0.59503 0.59191 -0.01419 -0.02100 -0.01779 169 PHE A C   
1451 C C   B PHE A 169 ? 0.60828 0.60631 0.60416 -0.09581 -0.08222 -0.03894 169 PHE A C   
1452 O O   A PHE A 169 ? 0.43201 0.59212 0.54294 -0.06324 0.09707  0.02211  169 PHE A O   
1453 O O   B PHE A 169 ? 0.59621 0.60465 0.58229 -0.14948 -0.17957 -0.06960 169 PHE A O   
1454 C CB  A PHE A 169 ? 0.51354 0.50289 0.62482 0.12626  0.08466  -0.09012 169 PHE A CB  
1455 C CB  B PHE A 169 ? 0.44017 0.54115 0.60589 0.03192  0.00962  -0.06112 169 PHE A CB  
1456 C CG  A PHE A 169 ? 0.60513 0.53263 0.63354 0.06903  0.12133  -0.06085 169 PHE A CG  
1457 C CG  B PHE A 169 ? 0.51306 0.53031 0.61314 0.03462  0.05817  -0.04309 169 PHE A CG  
1458 C CD1 A PHE A 169 ? 0.61886 0.46771 0.63977 0.09469  0.17957  -0.08014 169 PHE A CD1 
1459 C CD1 B PHE A 169 ? 0.48823 0.52316 0.61984 0.04412  0.06759  -0.03634 169 PHE A CD1 
1460 C CD2 A PHE A 169 ? 0.52319 0.52630 0.64157 0.06254  0.13215  -0.04660 169 PHE A CD2 
1461 C CD2 B PHE A 169 ? 0.57560 0.50236 0.62089 0.10394  0.09945  -0.04459 169 PHE A CD2 
1462 C CE1 A PHE A 169 ? 0.50913 0.44278 0.64259 0.07643  0.18054  -0.06801 169 PHE A CE1 
1463 C CE1 B PHE A 169 ? 0.52919 0.51096 0.62096 0.05218  0.04454  -0.03898 169 PHE A CE1 
1464 C CE2 A PHE A 169 ? 0.47503 0.46954 0.63323 0.09902  0.06674  -0.05641 169 PHE A CE2 
1465 C CE2 B PHE A 169 ? 0.62287 0.50865 0.62561 0.05876  0.08071  -0.03385 169 PHE A CE2 
1466 C CZ  A PHE A 169 ? 0.54928 0.47036 0.64415 0.01128  0.09509  -0.07199 169 PHE A CZ  
1467 C CZ  B PHE A 169 ? 0.59714 0.51672 0.62876 0.03368  0.05498  -0.03917 169 PHE A CZ  
1468 N N   . GLY A 170 ? 0.59261 0.63844 0.62229 -0.11152 -0.04392 0.01391  170 GLY A N   
1469 C CA  . GLY A 170 ? 0.78640 0.70947 0.72489 -0.09895 -0.02271 -0.01267 170 GLY A CA  
1470 C C   . GLY A 170 ? 0.94557 0.76467 0.81884 -0.07283 -0.02007 -0.00379 170 GLY A C   
1471 O O   . GLY A 170 ? 1.13071 0.82840 0.82924 -0.13396 -0.01726 0.01521  170 GLY A O   
1472 N N   A LEU A 171 ? 0.83437 0.75059 0.84454 0.01298  -0.01070 0.00923  171 LEU A N   
1473 N N   B LEU A 171 ? 0.89138 0.79275 0.86621 -0.00423 -0.01516 0.00505  171 LEU A N   
1474 C CA  A LEU A 171 ? 0.81047 0.76970 0.86294 0.04293  0.01748  0.03313  171 LEU A CA  
1475 C CA  B LEU A 171 ? 0.91817 0.84350 0.91577 0.02185  0.01248  0.02031  171 LEU A CA  
1476 C C   A LEU A 171 ? 0.86523 0.79811 0.89649 -0.00802 0.09463  0.02160  171 LEU A C   
1477 C C   B LEU A 171 ? 1.04032 0.94136 0.98687 0.00159  0.08903  -0.00661 171 LEU A C   
1478 O O   A LEU A 171 ? 0.76114 0.74564 0.87070 -0.03752 0.13347  0.00631  171 LEU A O   
1479 O O   B LEU A 171 ? 1.05045 0.95569 0.98998 -0.03193 0.11261  -0.01628 171 LEU A O   
1480 C CB  A LEU A 171 ? 0.72014 0.77176 0.84696 0.02232  0.00358  0.07515  171 LEU A CB  
1481 C CB  B LEU A 171 ? 0.78551 0.79878 0.89846 0.00543  -0.02326 0.05979  171 LEU A CB  
1482 C CG  A LEU A 171 ? 0.69312 0.73772 0.83395 0.01636  -0.02603 0.13643  171 LEU A CG  
1483 C CG  B LEU A 171 ? 0.70229 0.71169 0.87738 0.00195  -0.03924 0.11579  171 LEU A CG  
1484 C CD1 A LEU A 171 ? 0.72602 0.77146 0.84774 0.00799  -0.04251 0.12811  171 LEU A CD1 
1485 C CD1 B LEU A 171 ? 0.74295 0.68739 0.87811 0.01358  -0.05362 0.10609  171 LEU A CD1 
1486 C CD2 A LEU A 171 ? 0.65022 0.70709 0.81718 0.04341  -0.00319 0.14372  171 LEU A CD2 
1487 C CD2 B LEU A 171 ? 0.64397 0.67130 0.86236 0.02153  -0.02415 0.12144  171 LEU A CD2 
1488 N N   A ALA A 172 ? 0.93533 0.88392 0.95149 -0.00086 0.12144  0.01270  172 ALA A N   
1489 N N   B ALA A 172 ? 1.15553 1.00599 1.05798 0.01453  0.12654  -0.00982 172 ALA A N   
1490 C CA  A ALA A 172 ? 0.98836 0.96221 0.99551 0.03873  0.12573  -0.00008 172 ALA A CA  
1491 C CA  B ALA A 172 ? 1.21414 1.06163 1.11023 0.02731  0.12437  -0.00913 172 ALA A CA  
1492 C C   A ALA A 172 ? 1.05818 1.03987 1.04116 0.08857  0.08978  -0.00004 172 ALA A C   
1493 C C   B ALA A 172 ? 1.26883 1.12227 1.15784 0.09230  0.07989  -0.01746 172 ALA A C   
1494 O O   A ALA A 172 ? 1.02769 1.04616 1.05042 0.11717  0.09309  0.00804  172 ALA A O   
1495 O O   B ALA A 172 ? 1.31887 1.15252 1.16005 0.12313  0.07612  -0.01253 172 ALA A O   
1496 C CB  A ALA A 172 ? 0.97544 0.96693 0.99421 0.00232  0.15706  0.00436  172 ALA A CB  
1497 C CB  B ALA A 172 ? 1.17577 1.06775 1.10332 0.01275  0.15854  0.00544  172 ALA A CB  
1498 N N   A ARG A 173 ? 1.14876 1.10305 1.07879 0.10302  0.04496  -0.00060 173 ARG A N   
1499 N N   B ARG A 173 ? 1.25280 1.15968 1.18937 0.09418  0.03728  -0.01063 173 ARG A N   
1500 C CA  A ARG A 173 ? 1.21789 1.14979 1.11836 0.09441  0.02198  -0.01440 173 ARG A CA  
1501 C CA  B ARG A 173 ? 1.24908 1.19619 1.21082 0.05346  -0.00239 -0.00506 173 ARG A CA  
1502 C C   A ARG A 173 ? 1.26365 1.17927 1.14240 0.11203  0.01411  -0.02445 173 ARG A C   
1503 C C   B ARG A 173 ? 1.24617 1.20666 1.21013 0.08505  -0.01044 -0.01030 173 ARG A C   
1504 O O   A ARG A 173 ? 1.30041 1.19185 1.14785 0.08663  0.00604  -0.03728 173 ARG A O   
1505 O O   B ARG A 173 ? 1.25117 1.20535 1.21964 0.06709  -0.01490 -0.02272 173 ARG A O   
1506 C CB  A ARG A 173 ? 1.20932 1.15546 1.12469 0.07740  0.03450  -0.02628 173 ARG A CB  
1507 C CB  B ARG A 173 ? 1.24169 1.20255 1.23210 -0.00413 -0.01566 -0.00739 173 ARG A CB  
1508 C CG  A ARG A 173 ? 1.20616 1.13327 1.13048 0.05773  0.06804  -0.03273 173 ARG A CG  
1509 C CG  B ARG A 173 ? 1.24297 1.20589 1.25108 -0.03022 -0.02179 -0.01166 173 ARG A CG  
1510 C CD  A ARG A 173 ? 1.18928 1.10251 1.14113 0.02146  0.10040  -0.03900 173 ARG A CD  
1511 C CD  B ARG A 173 ? 1.23007 1.21426 1.26301 -0.01633 -0.04140 -0.01396 173 ARG A CD  
1512 N NE  A ARG A 173 ? 1.19077 1.07280 1.15477 -0.01448 0.15863  -0.04365 173 ARG A NE  
1513 N NE  B ARG A 173 ? 1.20499 1.22366 1.26912 0.00968  -0.05784 -0.01909 173 ARG A NE  
1514 C CZ  A ARG A 173 ? 1.12177 1.03532 1.14114 -0.02071 0.20650  -0.04560 173 ARG A CZ  
1515 C CZ  B ARG A 173 ? 1.16192 1.23346 1.26865 0.04240  -0.08442 -0.01991 173 ARG A CZ  
1516 N NH1 A ARG A 173 ? 1.11196 1.02441 1.13075 0.00777  0.24084  -0.03299 173 ARG A NH1 
1517 N NH1 B ARG A 173 ? 1.15540 1.23864 1.27252 0.02118  -0.10151 -0.01562 173 ARG A NH1 
1518 N NH2 A ARG A 173 ? 1.02051 1.01373 1.12947 -0.05570 0.19333  -0.06749 173 ARG A NH2 
1519 N NH2 B ARG A 173 ? 1.13237 1.23219 1.26454 0.07499  -0.07975 -0.02341 173 ARG A NH2 
1520 N N   A HIS A 174 ? 1.25281 1.19284 1.15362 0.13592  0.01830  -0.02297 174 HIS A N   
1521 N N   B HIS A 174 ? 1.23110 1.20789 1.19410 0.12390  -0.00929 -0.00761 174 HIS A N   
1522 C CA  A HIS A 174 ? 1.21963 1.18945 1.16046 0.17588  0.02536  -0.03127 174 HIS A CA  
1523 C CA  B HIS A 174 ? 1.20890 1.19461 1.17494 0.17575  -0.00716 -0.01445 174 HIS A CA  
1524 C C   A HIS A 174 ? 1.10552 1.15129 1.14734 0.30489  0.04319  -0.00399 174 HIS A C   
1525 C C   B HIS A 174 ? 1.08821 1.14899 1.15295 0.31076  0.03010  0.00430  174 HIS A C   
1526 O O   A HIS A 174 ? 1.09621 1.16114 1.15888 0.37508  0.06713  -0.01496 174 HIS A O   
1527 O O   B HIS A 174 ? 1.03489 1.14652 1.16239 0.41517  0.06228  -0.00729 174 HIS A O   
1528 C CB  A HIS A 174 ? 1.26704 1.24638 1.17540 0.07588  0.01310  -0.05624 174 HIS A CB  
1529 C CB  B HIS A 174 ? 1.26265 1.24822 1.17359 0.09945  -0.04214 -0.03223 174 HIS A CB  
1530 C CG  A HIS A 174 ? 1.31930 1.29390 1.19003 -0.01465 0.00420  -0.07355 174 HIS A CG  
1531 C CG  B HIS A 174 ? 1.31852 1.29629 1.17102 0.02691  -0.07837 -0.04093 174 HIS A CG  
1532 N ND1 A HIS A 174 ? 1.31158 1.31032 1.19649 -0.06584 0.00211  -0.08219 174 HIS A ND1 
1533 N ND1 B HIS A 174 ? 1.31409 1.30832 1.16748 -0.00562 -0.10001 -0.04250 174 HIS A ND1 
1534 C CD2 A HIS A 174 ? 1.33251 1.29889 1.19740 -0.05683 -0.00182 -0.08576 174 HIS A CD2 
1535 C CD2 B HIS A 174 ? 1.35388 1.30750 1.17077 -0.00790 -0.09494 -0.04882 174 HIS A CD2 
1536 C CE1 A HIS A 174 ? 1.29368 1.31341 1.20059 -0.07538 0.00863  -0.09003 174 HIS A CE1 
1537 C CE1 B HIS A 174 ? 1.32405 1.31511 1.16440 -0.02102 -0.10312 -0.04570 174 HIS A CE1 
1538 N NE2 A HIS A 174 ? 1.30956 1.31304 1.20184 -0.06491 0.00287  -0.09317 174 HIS A NE2 
1539 N NE2 B HIS A 174 ? 1.35238 1.32257 1.16744 -0.01636 -0.10277 -0.05074 174 HIS A NE2 
1540 N N   . THR A 175 ? 1.01091 1.10684 1.11707 0.31964  0.04005  0.03864  175 THR A N   
1541 C CA  . THR A 175 ? 0.94481 0.99868 1.06188 0.23804  0.03989  0.10006  175 THR A CA  
1542 C C   . THR A 175 ? 0.89267 0.94690 1.01869 0.17092  0.09810  0.16390  175 THR A C   
1543 O O   . THR A 175 ? 0.83024 0.93650 0.99901 0.23633  0.08321  0.19899  175 THR A O   
1544 C CB  . THR A 175 ? 0.92245 0.93058 1.05142 0.25218  -0.00918 0.12240  175 THR A CB  
1545 O OG1 . THR A 175 ? 0.88772 0.85613 1.04415 0.29686  -0.08931 0.13238  175 THR A OG1 
1546 C CG2 . THR A 175 ? 0.91828 0.92311 1.05136 0.20897  -0.01570 0.13689  175 THR A CG2 
1547 N N   . ASP A 176 ? 0.81167 0.94904 0.99199 0.06662  0.13009  0.17316  176 ASP A N   
1548 C CA  . ASP A 176 ? 0.70137 0.92640 0.96071 0.00241  0.14401  0.16506  176 ASP A CA  
1549 C C   . ASP A 176 ? 0.66090 0.86020 0.91031 0.02930  0.06268  0.14314  176 ASP A C   
1550 O O   . ASP A 176 ? 0.51812 0.88391 0.88327 -0.00865 0.01137  0.16827  176 ASP A O   
1551 C CB  . ASP A 176 ? 0.80995 0.96011 0.98595 0.05014  0.15718  0.18008  176 ASP A CB  
1552 C CG  . ASP A 176 ? 0.82711 0.99264 1.03652 0.07205  0.13918  0.17248  176 ASP A CG  
1553 O OD1 . ASP A 176 ? 0.82326 0.98631 1.04576 0.20409  0.18435  0.15448  176 ASP A OD1 
1554 O OD2 . ASP A 176 ? 0.72937 1.02081 1.06833 0.01399  0.10582  0.14390  176 ASP A OD2 
1555 N N   . ASP A 177 ? 0.63157 0.77835 0.86699 0.06322  -0.00922 0.12117  177 ASP A N   
1556 C CA  . ASP A 177 ? 0.79885 0.78291 0.81479 0.01056  0.03370  0.07583  177 ASP A CA  
1557 C C   . ASP A 177 ? 0.91226 0.76287 0.75537 0.11756  0.03594  0.08286  177 ASP A C   
1558 O O   . ASP A 177 ? 0.99720 0.72774 0.72205 0.16606  0.10986  0.09212  177 ASP A O   
1559 C CB  . ASP A 177 ? 0.87359 0.78570 0.83473 0.00525  0.05516  0.03152  177 ASP A CB  
1560 C CG  . ASP A 177 ? 1.08286 0.80058 0.84336 0.03272  0.00523  0.01980  177 ASP A CG  
1561 O OD1 . ASP A 177 ? 1.10818 0.78095 0.83691 0.00954  0.03066  0.00854  177 ASP A OD1 
1562 O OD2 . ASP A 177 ? 1.17537 0.82461 0.86715 0.08148  0.00116  0.02562  177 ASP A OD2 
1563 N N   . GLU A 178 ? 0.82866 0.71172 0.74139 0.10972  -0.11778 0.06273  178 GLU A N   
1564 C CA  . GLU A 178 ? 0.84810 0.69756 0.74833 0.14595  -0.16179 0.07635  178 GLU A CA  
1565 C C   . GLU A 178 ? 0.91640 0.58490 0.63476 0.18473  -0.18790 0.03266  178 GLU A C   
1566 O O   . GLU A 178 ? 1.13310 0.49777 0.54416 0.15770  -0.25330 0.00201  178 GLU A O   
1567 C CB  . GLU A 178 ? 0.81194 0.80965 0.87851 0.14645  -0.10754 0.10412  178 GLU A CB  
1568 C CG  . GLU A 178 ? 0.92683 0.92696 0.99377 0.09098  -0.01912 0.12504  178 GLU A CG  
1569 C CD  . GLU A 178 ? 1.07638 1.02514 1.08811 0.00470  -0.00915 0.14770  178 GLU A CD  
1570 O OE1 . GLU A 178 ? 1.08622 1.05124 1.11864 -0.03326 0.03869  0.18600  178 GLU A OE1 
1571 O OE2 . GLU A 178 ? 1.12194 1.07946 1.12325 -0.04317 0.01254  0.13451  178 GLU A OE2 
1572 N N   . MET A 179 ? 0.61803 0.53622 0.58584 0.18339  -0.17372 0.02415  179 MET A N   
1573 C CA  . MET A 179 ? 0.45922 0.51502 0.57696 0.18286  -0.07043 0.00077  179 MET A CA  
1574 C C   . MET A 179 ? 0.38214 0.41780 0.48021 0.03704  -0.00860 -0.01622 179 MET A C   
1575 O O   . MET A 179 ? 0.43635 0.40976 0.41924 0.00996  0.01669  -0.03713 179 MET A O   
1576 C CB  . MET A 179 ? 0.60061 0.59510 0.64102 0.14886  -0.00536 -0.05908 179 MET A CB  
1577 C CG  . MET A 179 ? 0.87517 0.69099 0.68447 0.06260  -0.02711 -0.10750 179 MET A CG  
1578 S SD  . MET A 179 ? 1.06897 0.74931 0.71902 0.00172  -0.03956 -0.10436 179 MET A SD  
1579 C CE  . MET A 179 ? 0.94283 0.79575 0.74634 -0.07144 -0.01732 -0.14216 179 MET A CE  
1580 N N   . THR A 180 ? 0.40359 0.37451 0.42486 -0.00088 0.00756  -0.02438 180 THR A N   
1581 C CA  . THR A 180 ? 0.43632 0.37376 0.44344 -0.03992 -0.03202 -0.06561 180 THR A CA  
1582 C C   . THR A 180 ? 0.50645 0.39315 0.37568 -0.10186 -0.00605 -0.05951 180 THR A C   
1583 O O   . THR A 180 ? 0.46197 0.44553 0.35655 -0.02974 -0.01850 -0.01358 180 THR A O   
1584 C CB  . THR A 180 ? 0.35831 0.42951 0.46186 -0.04003 -0.06076 -0.08864 180 THR A CB  
1585 O OG1 . THR A 180 ? 0.41814 0.47937 0.46020 -0.03095 -0.06735 -0.10116 180 THR A OG1 
1586 C CG2 . THR A 180 ? 0.41783 0.45421 0.47851 0.01552  0.01503  -0.09699 180 THR A CG2 
1587 N N   . GLY A 181 ? 0.54352 0.37626 0.33648 -0.11516 -0.00634 -0.07490 181 GLY A N   
1588 C CA  . GLY A 181 ? 0.50650 0.35974 0.35396 -0.11935 0.00086  -0.05529 181 GLY A CA  
1589 C C   . GLY A 181 ? 0.46017 0.38447 0.37863 -0.11426 0.01598  0.00112  181 GLY A C   
1590 O O   . GLY A 181 ? 0.43526 0.40798 0.41036 -0.04886 0.01075  -0.00750 181 GLY A O   
1591 N N   . TYR A 182 ? 0.46591 0.34919 0.36981 -0.03771 -0.00420 0.01061  182 TYR A N   
1592 C CA  . TYR A 182 ? 0.35812 0.36189 0.37507 -0.02249 0.02113  0.02078  182 TYR A CA  
1593 C C   . TYR A 182 ? 0.43842 0.38570 0.32849 0.02033  0.09599  0.01551  182 TYR A C   
1594 O O   . TYR A 182 ? 0.52841 0.43699 0.31846 -0.02477 0.01114  0.04060  182 TYR A O   
1595 C CB  . TYR A 182 ? 0.31989 0.36026 0.39648 -0.01604 0.02204  -0.02739 182 TYR A CB  
1596 C CG  . TYR A 182 ? 0.35233 0.36158 0.39010 -0.04721 -0.00588 -0.02747 182 TYR A CG  
1597 C CD1 . TYR A 182 ? 0.36390 0.33551 0.35970 -0.04335 0.01547  -0.00812 182 TYR A CD1 
1598 C CD2 . TYR A 182 ? 0.35329 0.38250 0.39827 -0.00994 0.01789  -0.00303 182 TYR A CD2 
1599 C CE1 . TYR A 182 ? 0.27402 0.39908 0.35396 -0.06843 0.04024  -0.00121 182 TYR A CE1 
1600 C CE2 . TYR A 182 ? 0.39201 0.44209 0.41063 -0.02018 0.01745  -0.00986 182 TYR A CE2 
1601 C CZ  . TYR A 182 ? 0.38943 0.42321 0.40461 -0.01130 -0.01609 -0.02814 182 TYR A CZ  
1602 O OH  . TYR A 182 ? 0.36114 0.49567 0.46225 -0.03599 0.00809  -0.06579 182 TYR A OH  
1603 N N   . VAL A 183 ? 0.42495 0.42242 0.34084 -0.00239 0.03413  -0.06544 183 VAL A N   
1604 C CA  . VAL A 183 ? 0.48832 0.41947 0.38543 0.03970  0.02157  -0.05669 183 VAL A CA  
1605 C C   . VAL A 183 ? 0.48082 0.38144 0.40039 -0.02194 -0.05930 -0.02722 183 VAL A C   
1606 O O   . VAL A 183 ? 0.38318 0.37658 0.46495 0.01442  -0.07273 -0.04475 183 VAL A O   
1607 C CB  . VAL A 183 ? 0.46733 0.40750 0.37955 0.03026  0.03199  0.00845  183 VAL A CB  
1608 C CG1 . VAL A 183 ? 0.55800 0.43459 0.32557 0.08489  0.02721  0.00242  183 VAL A CG1 
1609 C CG2 . VAL A 183 ? 0.47233 0.34686 0.40760 -0.00162 -0.02122 0.04804  183 VAL A CG2 
1610 N N   . ALA A 184 ? 0.52568 0.33615 0.35440 0.06183  0.02700  -0.02718 184 ALA A N   
1611 C CA  . ALA A 184 ? 0.54553 0.37334 0.35673 0.04880  0.02221  0.01285  184 ALA A CA  
1612 C C   . ALA A 184 ? 0.59717 0.39262 0.37169 -0.07552 0.05192  0.00581  184 ALA A C   
1613 O O   . ALA A 184 ? 0.72579 0.37115 0.38416 0.00386  -0.00189 -0.04403 184 ALA A O   
1614 C CB  . ALA A 184 ? 0.60742 0.40445 0.33614 0.06595  -0.07642 0.06317  184 ALA A CB  
1615 N N   . THR A 185 ? 0.46855 0.43390 0.38938 -0.03365 -0.01531 0.06137  185 THR A N   
1616 C CA  . THR A 185 ? 0.52338 0.43584 0.38778 -0.06362 -0.02824 0.02625  185 THR A CA  
1617 C C   . THR A 185 ? 0.51822 0.43050 0.41960 -0.02975 -0.04704 -0.02163 185 THR A C   
1618 O O   . THR A 185 ? 0.49795 0.53626 0.44311 0.02040  -0.06952 0.00900  185 THR A O   
1619 C CB  . THR A 185 ? 0.62120 0.47562 0.40706 0.00945  -0.07286 0.02163  185 THR A CB  
1620 O OG1 . THR A 185 ? 0.59617 0.47600 0.44536 -0.00376 -0.08154 -0.02589 185 THR A OG1 
1621 C CG2 . THR A 185 ? 0.63528 0.53614 0.38568 0.02661  -0.11446 0.02170  185 THR A CG2 
1622 N N   . ARG A 186 ? 0.33814 0.38322 0.38541 0.00399  -0.08492 -0.04984 186 ARG A N   
1623 C CA  . ARG A 186 ? 0.39359 0.31966 0.39441 -0.01084 -0.06674 -0.05894 186 ARG A CA  
1624 C C   . ARG A 186 ? 0.36679 0.29983 0.38040 -0.01186 -0.03841 -0.01726 186 ARG A C   
1625 O O   . ARG A 186 ? 0.38195 0.31435 0.38514 -0.01195 -0.01364 0.02343  186 ARG A O   
1626 C CB  . ARG A 186 ? 0.31624 0.30972 0.39380 -0.00975 0.00987  -0.05991 186 ARG A CB  
1627 C CG  . ARG A 186 ? 0.31725 0.37998 0.37482 0.00988  -0.01408 -0.06225 186 ARG A CG  
1628 C CD  . ARG A 186 ? 0.30924 0.37041 0.37614 -0.05833 0.01413  -0.04676 186 ARG A CD  
1629 N NE  . ARG A 186 ? 0.36861 0.32119 0.38754 -0.07633 0.06470  -0.05183 186 ARG A NE  
1630 C CZ  . ARG A 186 ? 0.36417 0.33513 0.38504 -0.00763 0.04440  -0.06328 186 ARG A CZ  
1631 N NH1 . ARG A 186 ? 0.41803 0.34716 0.37214 -0.03937 0.02480  -0.06973 186 ARG A NH1 
1632 N NH2 . ARG A 186 ? 0.35106 0.30469 0.36498 -0.00026 0.01384  -0.02742 186 ARG A NH2 
1633 N N   . TRP A 187 ? 0.38205 0.25268 0.33706 -0.06941 -0.02550 -0.05759 187 TRP A N   
1634 C CA  . TRP A 187 ? 0.30960 0.33470 0.30678 -0.05864 -0.00517 -0.05194 187 TRP A CA  
1635 C C   . TRP A 187 ? 0.39738 0.31570 0.35612 -0.05543 0.01457  -0.04264 187 TRP A C   
1636 O O   . TRP A 187 ? 0.38416 0.34186 0.33695 0.00705  0.06455  -0.06868 187 TRP A O   
1637 C CB  . TRP A 187 ? 0.23444 0.41113 0.28085 -0.03814 0.04014  -0.00853 187 TRP A CB  
1638 C CG  . TRP A 187 ? 0.29295 0.35160 0.28064 0.00815  0.04486  -0.00775 187 TRP A CG  
1639 C CD1 . TRP A 187 ? 0.41655 0.32478 0.28396 0.02120  0.00521  -0.03464 187 TRP A CD1 
1640 C CD2 . TRP A 187 ? 0.44614 0.35553 0.29033 -0.06037 0.03092  -0.00760 187 TRP A CD2 
1641 N NE1 . TRP A 187 ? 0.37444 0.34144 0.27763 -0.08404 0.03809  -0.01018 187 TRP A NE1 
1642 C CE2 . TRP A 187 ? 0.37762 0.35605 0.31234 -0.11211 0.02058  0.00127  187 TRP A CE2 
1643 C CE3 . TRP A 187 ? 0.47985 0.34316 0.26562 -0.06702 -0.02216 -0.02412 187 TRP A CE3 
1644 C CZ2 . TRP A 187 ? 0.47688 0.37579 0.36012 -0.08367 -0.00288 -0.01485 187 TRP A CZ2 
1645 C CZ3 . TRP A 187 ? 0.49173 0.42611 0.31413 -0.01601 0.08666  -0.00872 187 TRP A CZ3 
1646 C CH2 . TRP A 187 ? 0.44957 0.40622 0.32533 -0.02178 0.05534  -0.01845 187 TRP A CH2 
1647 N N   . TYR A 188 ? 0.29940 0.32747 0.33288 0.03290  0.01953  -0.02451 188 TYR A N   
1648 C CA  . TYR A 188 ? 0.36091 0.34335 0.31191 0.00625  0.00491  0.02944  188 TYR A CA  
1649 C C   . TYR A 188 ? 0.43040 0.32764 0.30055 -0.05813 -0.00262 0.00103  188 TYR A C   
1650 O O   . TYR A 188 ? 0.36885 0.37589 0.31978 -0.05328 -0.00084 -0.05129 188 TYR A O   
1651 C CB  . TYR A 188 ? 0.30919 0.35798 0.32221 -0.04845 -0.01618 0.07816  188 TYR A CB  
1652 C CG  . TYR A 188 ? 0.28213 0.31934 0.31971 0.01417  -0.00328 0.02150  188 TYR A CG  
1653 C CD1 . TYR A 188 ? 0.38987 0.37622 0.31133 -0.03908 0.00948  0.01641  188 TYR A CD1 
1654 C CD2 . TYR A 188 ? 0.34639 0.33229 0.36152 -0.04058 0.00208  0.03122  188 TYR A CD2 
1655 C CE1 . TYR A 188 ? 0.39545 0.33699 0.33284 -0.00870 0.02291  -0.00151 188 TYR A CE1 
1656 C CE2 . TYR A 188 ? 0.38848 0.35565 0.33309 -0.05416 0.00218  0.04488  188 TYR A CE2 
1657 C CZ  . TYR A 188 ? 0.39225 0.34852 0.35148 -0.04162 0.01399  -0.00019 188 TYR A CZ  
1658 O OH  . TYR A 188 ? 0.37417 0.35104 0.37136 -0.05141 -0.00697 0.00469  188 TYR A OH  
1659 N N   . ARG A 189 ? 0.44524 0.32548 0.31651 -0.05643 0.00933  -0.01537 189 ARG A N   
1660 C CA  . ARG A 189 ? 0.46087 0.35705 0.30339 -0.07280 0.05014  -0.00970 189 ARG A CA  
1661 C C   . ARG A 189 ? 0.41776 0.33900 0.31557 0.00723  0.03235  0.02713  189 ARG A C   
1662 O O   . ARG A 189 ? 0.41021 0.36536 0.32199 -0.02625 0.01874  0.04722  189 ARG A O   
1663 C CB  . ARG A 189 ? 0.47484 0.48255 0.35734 -0.01790 0.05998  -0.05559 189 ARG A CB  
1664 C CG  . ARG A 189 ? 0.58774 0.69620 0.44652 0.00035  0.18024  -0.07074 189 ARG A CG  
1665 C CD  . ARG A 189 ? 0.68619 0.90291 0.57668 0.04700  0.19804  -0.03683 189 ARG A CD  
1666 N NE  . ARG A 189 ? 0.79689 1.06024 0.65434 0.07360  0.22900  -0.01246 189 ARG A NE  
1667 C CZ  . ARG A 189 ? 0.79060 1.14411 0.69805 0.04972  0.20719  -0.00924 189 ARG A CZ  
1668 N NH1 . ARG A 189 ? 0.81246 1.14247 0.72050 0.00126  0.18342  -0.01258 189 ARG A NH1 
1669 N NH2 . ARG A 189 ? 0.88019 1.16913 0.69834 -0.02181 0.15414  0.01376  189 ARG A NH2 
1670 N N   . ALA A 190 ? 0.42078 0.35775 0.34723 -0.04375 0.10262  -0.00126 190 ALA A N   
1671 C CA  . ALA A 190 ? 0.41938 0.32026 0.35084 -0.00329 0.08931  -0.01478 190 ALA A CA  
1672 C C   . ALA A 190 ? 0.44855 0.38025 0.38160 0.00571  0.09602  -0.05017 190 ALA A C   
1673 O O   . ALA A 190 ? 0.47397 0.34071 0.38296 -0.02618 0.07334  -0.04231 190 ALA A O   
1674 C CB  . ALA A 190 ? 0.41271 0.36479 0.35951 -0.06801 0.08474  -0.03248 190 ALA A CB  
1675 N N   . PRO A 191 ? 0.44366 0.38226 0.36631 -0.11415 0.02769  -0.02427 191 PRO A N   
1676 C CA  . PRO A 191 ? 0.40860 0.40880 0.40907 -0.06305 0.00500  -0.02165 191 PRO A CA  
1677 C C   . PRO A 191 ? 0.44701 0.41088 0.44582 -0.08052 0.04038  -0.05028 191 PRO A C   
1678 O O   . PRO A 191 ? 0.48614 0.39731 0.43757 -0.06587 0.03686  -0.02251 191 PRO A O   
1679 C CB  . PRO A 191 ? 0.56342 0.38967 0.38010 -0.07566 0.01334  -0.04138 191 PRO A CB  
1680 C CG  . PRO A 191 ? 0.55273 0.42978 0.41030 -0.08736 -0.01178 0.03811  191 PRO A CG  
1681 C CD  . PRO A 191 ? 0.43096 0.39340 0.39177 -0.14106 -0.01422 0.01959  191 PRO A CD  
1682 N N   A GLU A 192 ? 0.43124 0.36691 0.44528 -0.05728 0.05770  -0.11066 192 GLU A N   
1683 N N   B GLU A 192 ? 0.43616 0.41143 0.46352 -0.06350 0.04623  -0.05559 192 GLU A N   
1684 C CA  A GLU A 192 ? 0.35677 0.37319 0.47011 -0.01720 0.08157  -0.09060 192 GLU A CA  
1685 C CA  B GLU A 192 ? 0.45405 0.42343 0.47884 -0.02844 0.05190  -0.04902 192 GLU A CA  
1686 C C   A GLU A 192 ? 0.54219 0.43073 0.51253 -0.11197 0.02655  -0.07440 192 GLU A C   
1687 C C   B GLU A 192 ? 0.49426 0.44457 0.49135 -0.06456 0.05062  -0.05321 192 GLU A C   
1688 O O   A GLU A 192 ? 0.49036 0.39947 0.55179 -0.02762 0.01045  -0.06672 192 GLU A O   
1689 O O   B GLU A 192 ? 0.53052 0.41600 0.50951 -0.02005 0.04591  -0.08246 192 GLU A O   
1690 C CB  A GLU A 192 ? 0.42869 0.36033 0.46927 -0.05185 0.09560  -0.04541 192 GLU A CB  
1691 C CB  B GLU A 192 ? 0.47613 0.42762 0.47968 0.00842  0.04854  -0.04216 192 GLU A CB  
1692 C CG  A GLU A 192 ? 0.44543 0.38354 0.45625 0.01321  0.02869  -0.04313 192 GLU A CG  
1693 C CG  B GLU A 192 ? 0.50166 0.43289 0.47268 0.02813  0.04489  -0.02721 192 GLU A CG  
1694 C CD  A GLU A 192 ? 0.58750 0.37459 0.37636 0.08136  -0.01079 -0.03924 192 GLU A CD  
1695 C CD  B GLU A 192 ? 0.48774 0.43134 0.45741 0.03058  0.05784  -0.00957 192 GLU A CD  
1696 O OE1 A GLU A 192 ? 0.66176 0.39395 0.36628 0.16407  -0.07912 -0.00522 192 GLU A OE1 
1697 O OE1 B GLU A 192 ? 0.40114 0.40746 0.45059 -0.00468 0.09291  0.02119  192 GLU A OE1 
1698 O OE2 A GLU A 192 ? 0.46613 0.36816 0.32688 0.01897  -0.00956 0.00627  192 GLU A OE2 
1699 O OE2 B GLU A 192 ? 0.51120 0.44895 0.45496 0.05792  0.04520  -0.01773 192 GLU A OE2 
1700 N N   . ILE A 193 ? 0.46292 0.48109 0.48000 -0.11786 0.07586  -0.03831 193 ILE A N   
1701 C CA  . ILE A 193 ? 0.46366 0.50536 0.53343 -0.11245 0.06427  -0.05193 193 ILE A CA  
1702 C C   . ILE A 193 ? 0.42439 0.41776 0.57337 -0.15083 0.04611  -0.04596 193 ILE A C   
1703 O O   . ILE A 193 ? 0.47195 0.46183 0.63345 -0.08735 -0.01596 -0.08298 193 ILE A O   
1704 C CB  . ILE A 193 ? 0.63137 0.62312 0.60648 0.13684  0.07548  -0.08922 193 ILE A CB  
1705 C CG1 . ILE A 193 ? 0.86257 0.68673 0.66258 0.02261  0.02824  -0.11842 193 ILE A CG1 
1706 C CG2 . ILE A 193 ? 0.80886 0.66469 0.66258 0.19260  0.02190  -0.05781 193 ILE A CG2 
1707 C CD1 . ILE A 193 ? 0.97966 0.73832 0.70285 -0.04787 0.01594  -0.10712 193 ILE A CD1 
1708 N N   . MET A 194 ? 0.37575 0.42515 0.55444 -0.10331 0.02130  0.00463  194 MET A N   
1709 C CA  . MET A 194 ? 0.37244 0.42679 0.50796 -0.04885 0.04118  0.01179  194 MET A CA  
1710 C C   . MET A 194 ? 0.44627 0.45106 0.46503 -0.08757 -0.01313 -0.02172 194 MET A C   
1711 O O   . MET A 194 ? 0.56499 0.47558 0.43313 -0.03547 0.09356  -0.00790 194 MET A O   
1712 C CB  . MET A 194 ? 0.27647 0.53741 0.49412 -0.05203 0.08829  -0.02280 194 MET A CB  
1713 C CG  . MET A 194 ? 0.41896 0.49298 0.43848 -0.16523 0.10565  -0.04856 194 MET A CG  
1714 S SD  . MET A 194 ? 0.45473 0.51211 0.38985 -0.06873 0.04437  -0.03047 194 MET A SD  
1715 C CE  . MET A 194 ? 0.42727 0.53286 0.33202 -0.10722 0.01983  -0.02027 194 MET A CE  
1716 N N   A LEU A 195 ? 0.39519 0.46868 0.45701 -0.12151 -0.03803 0.02678  195 LEU A N   
1717 N N   B LEU A 195 ? 0.39450 0.46307 0.45406 -0.11080 -0.03892 0.01653  195 LEU A N   
1718 C CA  A LEU A 195 ? 0.44034 0.48597 0.49631 -0.06814 -0.05322 0.03376  195 LEU A CA  
1719 C CA  B LEU A 195 ? 0.42252 0.47699 0.48626 -0.04283 -0.05555 0.01298  195 LEU A CA  
1720 C C   A LEU A 195 ? 0.46587 0.48113 0.51800 -0.05624 -0.02543 -0.01353 195 LEU A C   
1721 C C   B LEU A 195 ? 0.44640 0.47579 0.49905 -0.02279 -0.04819 -0.05085 195 LEU A C   
1722 O O   A LEU A 195 ? 0.50825 0.43722 0.55039 0.00926  -0.00527 -0.02647 195 LEU A O   
1723 O O   B LEU A 195 ? 0.44389 0.42554 0.49620 0.05659  -0.07697 -0.10279 195 LEU A O   
1724 C CB  A LEU A 195 ? 0.39285 0.51240 0.52249 -0.09049 -0.04440 0.07106  195 LEU A CB  
1725 C CB  B LEU A 195 ? 0.32741 0.49315 0.49797 -0.06820 -0.03696 0.05334  195 LEU A CB  
1726 C CG  A LEU A 195 ? 0.52039 0.51519 0.52936 -0.11257 -0.03330 0.09708  195 LEU A CG  
1727 C CG  B LEU A 195 ? 0.34125 0.46878 0.48309 -0.10066 -0.02406 0.07229  195 LEU A CG  
1728 C CD1 A LEU A 195 ? 0.46259 0.54009 0.49404 -0.07328 -0.04962 0.09869  195 LEU A CD1 
1729 C CD1 B LEU A 195 ? 0.30655 0.43918 0.47899 -0.06893 -0.15745 0.10719  195 LEU A CD1 
1730 C CD2 A LEU A 195 ? 0.61412 0.49854 0.54980 -0.14231 0.01373  0.11491  195 LEU A CD2 
1731 C CD2 B LEU A 195 ? 0.29351 0.49655 0.45318 -0.04903 0.12450  0.08476  195 LEU A CD2 
1732 N N   . ASN A 196 ? 0.50357 0.54221 0.51824 -0.05435 -0.00736 -0.07754 196 ASN A N   
1733 C CA  . ASN A 196 ? 0.69550 0.54744 0.57828 -0.08257 0.01712  -0.12522 196 ASN A CA  
1734 C C   . ASN A 196 ? 0.54870 0.45606 0.58274 -0.16741 0.05028  -0.10414 196 ASN A C   
1735 O O   . ASN A 196 ? 0.62924 0.41617 0.59995 -0.15840 0.04982  -0.02987 196 ASN A O   
1736 C CB  . ASN A 196 ? 0.79266 0.66340 0.68798 -0.03157 -0.04579 -0.12386 196 ASN A CB  
1737 C CG  . ASN A 196 ? 0.95411 0.86018 0.81828 0.02899  -0.07510 -0.14221 196 ASN A CG  
1738 O OD1 . ASN A 196 ? 1.02462 0.91497 0.86537 -0.02957 -0.14451 -0.12618 196 ASN A OD1 
1739 N ND2 . ASN A 196 ? 0.98662 0.90573 0.91354 0.13749  0.05526  -0.16099 196 ASN A ND2 
1740 N N   . TRP A 197 ? 0.43107 0.51596 0.55387 -0.08997 0.09604  -0.10345 197 TRP A N   
1741 C CA  . TRP A 197 ? 0.31929 0.53134 0.58082 -0.11617 0.07761  -0.07527 197 TRP A CA  
1742 C C   . TRP A 197 ? 0.39227 0.53955 0.62113 -0.10255 -0.00821 -0.08773 197 TRP A C   
1743 O O   . TRP A 197 ? 0.51581 0.52939 0.61647 -0.04694 -0.03507 -0.10391 197 TRP A O   
1744 C CB  . TRP A 197 ? 0.50367 0.51031 0.58990 -0.07027 -0.00221 -0.06030 197 TRP A CB  
1745 C CG  . TRP A 197 ? 0.44084 0.50642 0.59905 -0.06182 0.04477  0.02986  197 TRP A CG  
1746 C CD1 . TRP A 197 ? 0.53691 0.45514 0.59765 -0.01577 0.09942  0.06208  197 TRP A CD1 
1747 C CD2 . TRP A 197 ? 0.50291 0.47677 0.59433 -0.13348 -0.02416 0.07284  197 TRP A CD2 
1748 N NE1 . TRP A 197 ? 0.54855 0.40936 0.59350 -0.02036 0.02302  0.07828  197 TRP A NE1 
1749 C CE2 . TRP A 197 ? 0.40681 0.45712 0.59264 -0.10989 0.00930  0.10776  197 TRP A CE2 
1750 C CE3 . TRP A 197 ? 0.52770 0.49531 0.61597 0.01368  -0.05100 0.09733  197 TRP A CE3 
1751 C CZ2 . TRP A 197 ? 0.51881 0.49089 0.58108 -0.11394 0.00254  0.11100  197 TRP A CZ2 
1752 C CZ3 . TRP A 197 ? 0.59300 0.50462 0.60041 -0.05048 -0.06732 0.10317  197 TRP A CZ3 
1753 C CH2 . TRP A 197 ? 0.57811 0.51120 0.58785 -0.05227 -0.00683 0.13391  197 TRP A CH2 
1754 N N   . MET A 198 ? 0.40418 0.61829 0.63825 0.02124  0.05068  -0.12947 198 MET A N   
1755 C CA  . MET A 198 ? 0.52699 0.66958 0.66462 -0.02091 -0.02198 -0.11079 198 MET A CA  
1756 C C   . MET A 198 ? 0.65891 0.69812 0.70791 -0.06422 -0.08538 -0.09670 198 MET A C   
1757 O O   . MET A 198 ? 0.63169 0.61142 0.65102 -0.12861 -0.13093 -0.08890 198 MET A O   
1758 C CB  . MET A 198 ? 0.64342 0.68530 0.64308 -0.03579 -0.01784 -0.14405 198 MET A CB  
1759 C CG  . MET A 198 ? 0.74151 0.72707 0.63343 0.04285  -0.00550 -0.15543 198 MET A CG  
1760 S SD  . MET A 198 ? 0.69323 0.79631 0.63637 0.01823  0.00987  -0.14444 198 MET A SD  
1761 C CE  . MET A 198 ? 0.50345 0.78565 0.59808 0.16869  0.01324  -0.12203 198 MET A CE  
1762 N N   . HIS A 199 ? 0.77625 0.79498 0.80867 -0.09449 -0.09785 -0.06542 199 HIS A N   
1763 C CA  . HIS A 199 ? 0.90262 0.90728 0.90634 -0.08691 -0.07119 -0.03651 199 HIS A CA  
1764 C C   . HIS A 199 ? 0.79954 0.82690 0.90820 -0.06831 -0.03304 -0.01025 199 HIS A C   
1765 O O   . HIS A 199 ? 1.06394 0.78471 0.92095 -0.18565 -0.03054 0.00481  199 HIS A O   
1766 C CB  . HIS A 199 ? 1.08660 1.10276 0.99281 -0.12074 -0.03384 -0.02216 199 HIS A CB  
1767 C CG  . HIS A 199 ? 1.21333 1.28497 1.07765 -0.13843 -0.04658 -0.01396 199 HIS A CG  
1768 N ND1 . HIS A 199 ? 1.29962 1.36676 1.12107 -0.15604 -0.06074 0.00058  199 HIS A ND1 
1769 C CD2 . HIS A 199 ? 1.22168 1.35332 1.10639 -0.14795 -0.04870 -0.01093 199 HIS A CD2 
1770 C CE1 . HIS A 199 ? 1.30034 1.39679 1.13274 -0.15758 -0.06628 -0.00681 199 HIS A CE1 
1771 N NE2 . HIS A 199 ? 1.25929 1.39939 1.12668 -0.15783 -0.04917 -0.00480 199 HIS A NE2 
1772 N N   . TYR A 200 ? 0.48621 0.78366 0.89931 -0.00099 0.01497  0.02188  200 TYR A N   
1773 C CA  . TYR A 200 ? 0.61568 0.74843 0.89577 -0.01947 0.07383  0.09493  200 TYR A CA  
1774 C C   . TYR A 200 ? 0.68898 0.72219 0.86700 0.05232  0.05510  0.11734  200 TYR A C   
1775 O O   . TYR A 200 ? 0.79226 0.75669 0.88948 0.10601  0.01177  0.12216  200 TYR A O   
1776 C CB  . TYR A 200 ? 0.61280 0.75733 0.91088 -0.12915 0.09274  0.13064  200 TYR A CB  
1777 C CG  . TYR A 200 ? 0.61588 0.76496 0.91644 -0.19842 0.01298  0.15201  200 TYR A CG  
1778 C CD1 . TYR A 200 ? 0.85181 0.78895 0.93615 -0.14617 -0.06954 0.15009  200 TYR A CD1 
1779 C CD2 . TYR A 200 ? 0.68733 0.78535 0.92601 -0.13712 -0.03992 0.14812  200 TYR A CD2 
1780 C CE1 . TYR A 200 ? 1.06455 0.81358 0.96403 -0.11915 -0.09622 0.13233  200 TYR A CE1 
1781 C CE2 . TYR A 200 ? 0.85679 0.81060 0.96001 -0.13620 -0.08164 0.12570  200 TYR A CE2 
1782 C CZ  . TYR A 200 ? 1.14033 0.79913 0.97405 -0.11595 -0.09407 0.11902  200 TYR A CZ  
1783 O OH  . TYR A 200 ? 1.35396 0.80772 0.98631 -0.11236 -0.13005 0.10661  200 TYR A OH  
1784 N N   . ASN A 201 ? 0.66424 0.63894 0.80515 0.07973  0.11511  0.13536  201 ASN A N   
1785 C CA  . ASN A 201 ? 0.73009 0.55598 0.73264 0.05759  0.12900  0.16529  201 ASN A CA  
1786 C C   . ASN A 201 ? 0.49362 0.45937 0.66195 0.05773  0.05770  0.16131  201 ASN A C   
1787 O O   . ASN A 201 ? 0.41044 0.39738 0.63332 -0.04795 0.04638  0.11484  201 ASN A O   
1788 C CB  . ASN A 201 ? 0.83511 0.59720 0.70791 0.07557  0.18839  0.23650  201 ASN A CB  
1789 C CG  . ASN A 201 ? 0.87286 0.65329 0.70054 0.09733  0.21605  0.32405  201 ASN A CG  
1790 O OD1 . ASN A 201 ? 1.09775 0.66105 0.71457 0.06044  0.12981  0.30173  201 ASN A OD1 
1791 N ND2 . ASN A 201 ? 0.84699 0.70110 0.76196 0.08169  0.19879  0.32534  201 ASN A ND2 
1792 N N   . GLN A 202 ? 0.44246 0.43405 0.59785 -0.00407 0.03022  0.17884  202 GLN A N   
1793 C CA  . GLN A 202 ? 0.40741 0.39221 0.55586 -0.03822 -0.05346 0.14530  202 GLN A CA  
1794 C C   . GLN A 202 ? 0.24285 0.41745 0.43637 0.00101  -0.00099 0.06043  202 GLN A C   
1795 O O   . GLN A 202 ? 0.34978 0.40727 0.33565 -0.03060 0.01287  0.03214  202 GLN A O   
1796 C CB  . GLN A 202 ? 0.67619 0.43417 0.63206 0.00241  0.06500  0.06217  202 GLN A CB  
1797 C CG  . GLN A 202 ? 0.70587 0.49194 0.70268 0.00077  0.03585  0.12925  202 GLN A CG  
1798 C CD  . GLN A 202 ? 0.63517 0.48610 0.74794 -0.01714 0.01335  0.16326  202 GLN A CD  
1799 O OE1 . GLN A 202 ? 0.83143 0.55641 0.81855 0.00165  -0.02945 0.13038  202 GLN A OE1 
1800 N NE2 . GLN A 202 ? 0.64962 0.45521 0.71321 -0.00219 0.14133  0.17911  202 GLN A NE2 
1801 N N   . THR A 203 ? 0.36619 0.47820 0.42692 0.08992  0.04888  0.04304  203 THR A N   
1802 C CA  . THR A 203 ? 0.40366 0.56551 0.42440 0.13722  0.09523  0.04682  203 THR A CA  
1803 C C   . THR A 203 ? 0.36594 0.46009 0.40673 -0.00917 0.01395  0.00663  203 THR A C   
1804 O O   . THR A 203 ? 0.42629 0.36879 0.34498 -0.02681 0.00349  -0.03935 203 THR A O   
1805 C CB  . THR A 203 ? 0.46866 0.79115 0.46214 0.09646  0.11248  0.12360  203 THR A CB  
1806 O OG1 . THR A 203 ? 0.90953 0.88777 0.52071 0.13751  0.00031  0.16405  203 THR A OG1 
1807 C CG2 . THR A 203 ? 0.59268 0.85604 0.50549 0.17401  0.11875  0.10959  203 THR A CG2 
1808 N N   . VAL A 204 ? 0.38991 0.43210 0.43432 -0.00538 -0.00833 0.03952  204 VAL A N   
1809 C CA  . VAL A 204 ? 0.40987 0.40503 0.40544 -0.06291 0.03254  0.02288  204 VAL A CA  
1810 C C   . VAL A 204 ? 0.40143 0.37630 0.38255 -0.10299 -0.02496 0.00824  204 VAL A C   
1811 O O   . VAL A 204 ? 0.40332 0.40881 0.36604 -0.02416 0.00807  -0.03258 204 VAL A O   
1812 C CB  . VAL A 204 ? 0.40463 0.34459 0.39647 -0.08321 -0.03023 0.01852  204 VAL A CB  
1813 C CG1 . VAL A 204 ? 0.40458 0.32904 0.42654 -0.03300 0.01164  -0.02427 204 VAL A CG1 
1814 C CG2 . VAL A 204 ? 0.53413 0.39887 0.39264 -0.16414 -0.16737 -0.02056 204 VAL A CG2 
1815 N N   . ASP A 205 ? 0.29853 0.37866 0.37609 0.03098  -0.00310 0.00712  205 ASP A N   
1816 C CA  . ASP A 205 ? 0.30841 0.39251 0.36332 -0.00164 -0.01515 -0.00293 205 ASP A CA  
1817 C C   . ASP A 205 ? 0.26689 0.41544 0.32439 -0.05082 -0.00740 -0.04974 205 ASP A C   
1818 O O   . ASP A 205 ? 0.29752 0.42648 0.36072 -0.06208 -0.01803 -0.05959 205 ASP A O   
1819 C CB  . ASP A 205 ? 0.22820 0.46184 0.35064 0.00733  -0.06609 0.02305  205 ASP A CB  
1820 C CG  . ASP A 205 ? 0.37363 0.46027 0.35983 0.06331  0.00764  -0.00129 205 ASP A CG  
1821 O OD1 . ASP A 205 ? 0.38080 0.46164 0.35520 -0.04204 -0.05657 0.00095  205 ASP A OD1 
1822 O OD2 . ASP A 205 ? 0.31803 0.45841 0.34938 0.05050  0.03162  -0.04432 205 ASP A OD2 
1823 N N   . ILE A 206 ? 0.28929 0.42158 0.26656 -0.04382 -0.04410 -0.03933 206 ILE A N   
1824 C CA  . ILE A 206 ? 0.25581 0.39621 0.26784 0.00206  -0.00226 -0.05919 206 ILE A CA  
1825 C C   . ILE A 206 ? 0.27643 0.36581 0.28402 -0.02738 0.01924  -0.01549 206 ILE A C   
1826 O O   . ILE A 206 ? 0.37631 0.36645 0.28236 0.01719  -0.01839 -0.00577 206 ILE A O   
1827 C CB  . ILE A 206 ? 0.29295 0.35416 0.31251 0.09370  0.00070  -0.07151 206 ILE A CB  
1828 C CG1 . ILE A 206 ? 0.32242 0.27057 0.36900 0.09110  0.00521  -0.03015 206 ILE A CG1 
1829 C CG2 . ILE A 206 ? 0.35740 0.46069 0.33943 0.04407  0.00291  -0.06740 206 ILE A CG2 
1830 C CD1 . ILE A 206 ? 0.45890 0.36576 0.41460 0.12602  -0.00135 -0.06085 206 ILE A CD1 
1831 N N   . TRP A 207 ? 0.32501 0.36504 0.33661 0.00442  0.03486  -0.06691 207 TRP A N   
1832 C CA  . TRP A 207 ? 0.27083 0.24162 0.34262 -0.01844 0.08499  -0.02007 207 TRP A CA  
1833 C C   . TRP A 207 ? 0.21623 0.33749 0.34878 -0.02931 0.02718  -0.00603 207 TRP A C   
1834 O O   . TRP A 207 ? 0.25904 0.37985 0.30775 -0.03133 0.03055  0.00317  207 TRP A O   
1835 C CB  . TRP A 207 ? 0.31159 0.25421 0.37339 -0.00213 0.04617  -0.00731 207 TRP A CB  
1836 C CG  . TRP A 207 ? 0.26657 0.29929 0.34290 0.00418  0.01167  -0.01299 207 TRP A CG  
1837 C CD1 . TRP A 207 ? 0.27873 0.33405 0.32465 -0.00600 -0.01671 -0.04166 207 TRP A CD1 
1838 C CD2 . TRP A 207 ? 0.36986 0.32007 0.31275 0.03865  -0.02021 -0.07817 207 TRP A CD2 
1839 N NE1 . TRP A 207 ? 0.27337 0.34342 0.31590 -0.03837 -0.01448 0.02448  207 TRP A NE1 
1840 C CE2 . TRP A 207 ? 0.43036 0.28738 0.28749 -0.01358 0.03016  -0.00634 207 TRP A CE2 
1841 C CE3 . TRP A 207 ? 0.32371 0.30596 0.28463 0.01024  -0.02256 -0.05756 207 TRP A CE3 
1842 C CZ2 . TRP A 207 ? 0.50026 0.30063 0.25780 -0.01422 -0.08763 0.00022  207 TRP A CZ2 
1843 C CZ3 . TRP A 207 ? 0.42381 0.34654 0.29611 0.08134  -0.01929 -0.05585 207 TRP A CZ3 
1844 C CH2 . TRP A 207 ? 0.46298 0.35018 0.25821 -0.00178 -0.03120 0.01139  207 TRP A CH2 
1845 N N   . SER A 208 ? 0.36872 0.32477 0.33300 -0.02344 -0.05941 -0.03057 208 SER A N   
1846 C CA  . SER A 208 ? 0.28365 0.32936 0.32425 -0.10357 -0.03329 0.00237  208 SER A CA  
1847 C C   . SER A 208 ? 0.35501 0.32976 0.31844 -0.02857 -0.03997 -0.00158 208 SER A C   
1848 O O   . SER A 208 ? 0.37593 0.32255 0.32824 0.03801  -0.01419 0.02066  208 SER A O   
1849 C CB  . SER A 208 ? 0.32032 0.30683 0.32566 -0.03190 -0.06370 -0.05260 208 SER A CB  
1850 O OG  . SER A 208 ? 0.34742 0.37499 0.38343 0.00184  0.00176  -0.03831 208 SER A OG  
1851 N N   . VAL A 209 ? 0.33968 0.31716 0.32889 -0.02806 -0.00340 -0.01965 209 VAL A N   
1852 C CA  . VAL A 209 ? 0.35257 0.25617 0.34480 0.05908  0.03627  -0.03715 209 VAL A CA  
1853 C C   . VAL A 209 ? 0.38530 0.27963 0.33798 0.01962  0.01741  0.00270  209 VAL A C   
1854 O O   . VAL A 209 ? 0.35854 0.33004 0.36142 -0.04268 0.02624  -0.03513 209 VAL A O   
1855 C CB  . VAL A 209 ? 0.33068 0.26636 0.37818 0.02568  0.00644  -0.05225 209 VAL A CB  
1856 C CG1 . VAL A 209 ? 0.33700 0.24666 0.43547 -0.01437 0.00902  -0.07067 209 VAL A CG1 
1857 C CG2 . VAL A 209 ? 0.32507 0.37706 0.40895 0.04241  -0.04661 0.02527  209 VAL A CG2 
1858 N N   . GLY A 210 ? 0.26136 0.33686 0.29673 -0.02334 -0.01951 -0.06446 210 GLY A N   
1859 C CA  . GLY A 210 ? 0.23625 0.36919 0.31158 -0.04880 -0.01745 -0.01947 210 GLY A CA  
1860 C C   . GLY A 210 ? 0.33009 0.34419 0.33720 -0.05898 -0.00683 -0.02736 210 GLY A C   
1861 O O   . GLY A 210 ? 0.37715 0.30993 0.35764 -0.06957 -0.04517 -0.04025 210 GLY A O   
1862 N N   . CYS A 211 ? 0.35984 0.32603 0.26412 -0.04681 -0.01547 -0.02571 211 CYS A N   
1863 C CA  . CYS A 211 ? 0.31184 0.35230 0.32052 -0.01521 0.07550  -0.03642 211 CYS A CA  
1864 C C   . CYS A 211 ? 0.42644 0.31963 0.35078 0.00614  0.02569  -0.00900 211 CYS A C   
1865 O O   . CYS A 211 ? 0.36298 0.32692 0.32386 -0.01003 0.01760  0.00923  211 CYS A O   
1866 C CB  . CYS A 211 ? 0.38420 0.28845 0.33899 -0.01146 -0.01234 -0.02929 211 CYS A CB  
1867 S SG  . CYS A 211 ? 0.35556 0.30617 0.36090 -0.00044 -0.01596 -0.00805 211 CYS A SG  
1868 N N   . ILE A 212 ? 0.35681 0.27090 0.34606 -0.00378 0.01793  -0.00718 212 ILE A N   
1869 C CA  . ILE A 212 ? 0.39195 0.25164 0.35619 0.03784  -0.01314 0.00327  212 ILE A CA  
1870 C C   . ILE A 212 ? 0.33355 0.31293 0.40217 -0.00874 0.00882  0.00475  212 ILE A C   
1871 O O   . ILE A 212 ? 0.36171 0.35470 0.40153 -0.02651 -0.05590 -0.00107 212 ILE A O   
1872 C CB  . ILE A 212 ? 0.30133 0.22611 0.34740 0.02579  -0.05281 0.06289  212 ILE A CB  
1873 C CG1 . ILE A 212 ? 0.24955 0.32574 0.35954 -0.06721 -0.06522 0.04078  212 ILE A CG1 
1874 C CG2 . ILE A 212 ? 0.33175 0.25844 0.41233 0.01095  -0.01184 0.08100  212 ILE A CG2 
1875 C CD1 . ILE A 212 ? 0.28416 0.40467 0.36324 -0.01530 -0.09952 0.01048  212 ILE A CD1 
1876 N N   . MET A 213 ? 0.28906 0.37373 0.37128 0.02708  -0.03398 -0.00918 213 MET A N   
1877 C CA  . MET A 213 ? 0.29347 0.35366 0.35106 -0.04609 -0.15872 -0.03428 213 MET A CA  
1878 C C   . MET A 213 ? 0.16804 0.32635 0.38372 -0.03619 -0.08038 -0.00895 213 MET A C   
1879 O O   . MET A 213 ? 0.30066 0.29988 0.43742 -0.05374 0.00496  -0.07703 213 MET A O   
1880 C CB  . MET A 213 ? 0.36900 0.37357 0.29445 0.02688  -0.03334 -0.04099 213 MET A CB  
1881 C CG  . MET A 213 ? 0.38658 0.37839 0.33838 -0.02488 0.02963  -0.03956 213 MET A CG  
1882 S SD  . MET A 213 ? 0.37581 0.43261 0.36853 -0.00905 -0.02842 -0.08818 213 MET A SD  
1883 C CE  . MET A 213 ? 0.41408 0.48533 0.34556 -0.08150 -0.03489 -0.09017 213 MET A CE  
1884 N N   . ALA A 214 ? 0.33990 0.34254 0.36808 0.05628  -0.05198 0.01209  214 ALA A N   
1885 C CA  . ALA A 214 ? 0.33089 0.32441 0.36291 -0.01159 -0.01312 -0.02234 214 ALA A CA  
1886 C C   . ALA A 214 ? 0.39676 0.35232 0.39082 -0.06893 0.01271  -0.01030 214 ALA A C   
1887 O O   . ALA A 214 ? 0.40794 0.35231 0.41022 -0.02244 -0.02716 -0.04147 214 ALA A O   
1888 C CB  . ALA A 214 ? 0.36015 0.28197 0.35562 -0.00618 -0.07033 0.00041  214 ALA A CB  
1889 N N   . GLU A 215 ? 0.35575 0.36857 0.37255 -0.03277 -0.03861 -0.06644 215 GLU A N   
1890 C CA  . GLU A 215 ? 0.39580 0.37825 0.37539 -0.01346 0.00851  -0.03661 215 GLU A CA  
1891 C C   . GLU A 215 ? 0.39309 0.36511 0.40381 -0.03808 0.03372  -0.03003 215 GLU A C   
1892 O O   . GLU A 215 ? 0.39855 0.40811 0.40452 -0.03277 0.03054  -0.01987 215 GLU A O   
1893 C CB  . GLU A 215 ? 0.33176 0.39685 0.35588 -0.00852 0.01407  -0.05924 215 GLU A CB  
1894 C CG  . GLU A 215 ? 0.31621 0.45039 0.34766 -0.03766 0.00931  0.02920  215 GLU A CG  
1895 C CD  . GLU A 215 ? 0.41368 0.42211 0.29965 -0.08007 -0.04919 0.08891  215 GLU A CD  
1896 O OE1 . GLU A 215 ? 0.42250 0.41498 0.33276 -0.06775 -0.01579 0.02014  215 GLU A OE1 
1897 O OE2 . GLU A 215 ? 0.48438 0.51111 0.36369 -0.06819 -0.03766 0.01819  215 GLU A OE2 
1898 N N   . LEU A 216 ? 0.36924 0.25437 0.45751 -0.00081 0.04362  -0.03067 216 LEU A N   
1899 C CA  . LEU A 216 ? 0.28895 0.26072 0.49961 0.03398  -0.02448 -0.00706 216 LEU A CA  
1900 C C   . LEU A 216 ? 0.25770 0.31363 0.50636 0.02499  -0.00760 -0.01162 216 LEU A C   
1901 O O   . LEU A 216 ? 0.37946 0.34747 0.52175 -0.06879 -0.00348 -0.00594 216 LEU A O   
1902 C CB  . LEU A 216 ? 0.32726 0.34589 0.49550 0.05827  -0.00246 0.01143  216 LEU A CB  
1903 C CG  . LEU A 216 ? 0.38985 0.40693 0.47456 0.01497  -0.00532 0.04131  216 LEU A CG  
1904 C CD1 . LEU A 216 ? 0.31875 0.40021 0.50512 0.03933  -0.00407 0.03052  216 LEU A CD1 
1905 C CD2 . LEU A 216 ? 0.48640 0.47356 0.40761 0.03406  -0.02851 0.04482  216 LEU A CD2 
1906 N N   . LEU A 217 ? 0.27939 0.31178 0.44423 0.02263  -0.04263 -0.03453 217 LEU A N   
1907 C CA  . LEU A 217 ? 0.25550 0.37749 0.47833 -0.01155 -0.06457 -0.03209 217 LEU A CA  
1908 C C   . LEU A 217 ? 0.31793 0.34877 0.47460 -0.03007 0.00833  -0.03353 217 LEU A C   
1909 O O   . LEU A 217 ? 0.35255 0.41533 0.55209 -0.04883 -0.01339 -0.05646 217 LEU A O   
1910 C CB  . LEU A 217 ? 0.39431 0.38276 0.47082 0.02563  -0.07823 -0.05653 217 LEU A CB  
1911 C CG  . LEU A 217 ? 0.36760 0.38029 0.52155 0.03874  -0.05815 -0.08205 217 LEU A CG  
1912 C CD1 . LEU A 217 ? 0.48281 0.40172 0.49464 0.05017  -0.01690 -0.02923 217 LEU A CD1 
1913 C CD2 . LEU A 217 ? 0.47396 0.40494 0.55103 0.07537  0.04120  -0.10696 217 LEU A CD2 
1914 N N   . THR A 218 ? 0.33789 0.38722 0.39634 0.05378  -0.01851 -0.07439 218 THR A N   
1915 C CA  . THR A 218 ? 0.33134 0.40431 0.40186 0.05683  -0.02138 -0.01055 218 THR A CA  
1916 C C   . THR A 218 ? 0.35132 0.43284 0.44392 0.00301  0.00230  -0.04533 218 THR A C   
1917 O O   . THR A 218 ? 0.31775 0.38989 0.47933 -0.02665 0.02414  -0.04241 218 THR A O   
1918 C CB  . THR A 218 ? 0.36239 0.36013 0.38645 -0.03861 0.03121  -0.00622 218 THR A CB  
1919 O OG1 . THR A 218 ? 0.40499 0.34524 0.38050 -0.06037 0.01214  -0.03200 218 THR A OG1 
1920 C CG2 . THR A 218 ? 0.42030 0.37010 0.34822 -0.03948 -0.03907 0.02236  218 THR A CG2 
1921 N N   . GLY A 219 ? 0.35246 0.37873 0.40119 -0.10193 -0.03009 -0.01463 219 GLY A N   
1922 C CA  . GLY A 219 ? 0.41144 0.32723 0.34201 -0.06017 -0.04812 -0.03265 219 GLY A CA  
1923 C C   . GLY A 219 ? 0.42649 0.35934 0.37221 -0.00162 0.01539  -0.03552 219 GLY A C   
1924 O O   . GLY A 219 ? 0.49716 0.40326 0.40557 -0.04849 0.07890  -0.00938 219 GLY A O   
1925 N N   . ARG A 220 ? 0.42156 0.32288 0.36894 -0.01100 -0.00864 0.03099  220 ARG A N   
1926 C CA  . ARG A 220 ? 0.32801 0.36029 0.42248 -0.02253 0.02001  0.00461  220 ARG A CA  
1927 C C   . ARG A 220 ? 0.34816 0.33768 0.40947 -0.06861 0.01760  -0.00308 220 ARG A C   
1928 O O   . ARG A 220 ? 0.32011 0.34762 0.39539 -0.01199 -0.04645 -0.00266 220 ARG A O   
1929 C CB  . ARG A 220 ? 0.31330 0.39746 0.43832 0.00467  0.08733  0.01426  220 ARG A CB  
1930 C CG  . ARG A 220 ? 0.30167 0.41730 0.43480 -0.06792 0.06437  0.05865  220 ARG A CG  
1931 C CD  . ARG A 220 ? 0.27286 0.48678 0.41936 -0.03358 0.11733  0.07383  220 ARG A CD  
1932 N NE  . ARG A 220 ? 0.33217 0.47091 0.45032 -0.00429 0.14547  0.07379  220 ARG A NE  
1933 C CZ  . ARG A 220 ? 0.32331 0.53695 0.49427 -0.03671 0.17898  0.09280  220 ARG A CZ  
1934 N NH1 . ARG A 220 ? 0.40268 0.62702 0.50433 0.03014  0.07199  0.03785  220 ARG A NH1 
1935 N NH2 . ARG A 220 ? 0.40489 0.48911 0.52716 -0.08895 0.14401  0.09408  220 ARG A NH2 
1936 N N   . THR A 221 ? 0.39410 0.33961 0.36064 -0.05384 -0.00157 -0.03575 221 THR A N   
1937 C CA  . THR A 221 ? 0.36798 0.37272 0.32544 -0.01447 0.00376  -0.02603 221 THR A CA  
1938 C C   . THR A 221 ? 0.24845 0.36409 0.31822 -0.02387 0.00167  0.00012  221 THR A C   
1939 O O   . THR A 221 ? 0.28950 0.38321 0.34983 -0.01875 0.01025  -0.02674 221 THR A O   
1940 C CB  . THR A 221 ? 0.47404 0.40356 0.33658 -0.07488 -0.04795 -0.02966 221 THR A CB  
1941 O OG1 . THR A 221 ? 0.58640 0.41190 0.33845 -0.11751 -0.04190 0.01020  221 THR A OG1 
1942 C CG2 . THR A 221 ? 0.37550 0.38578 0.35954 -0.10757 0.00293  -0.05228 221 THR A CG2 
1943 N N   . LEU A 222 ? 0.29976 0.35000 0.32015 -0.06954 0.03319  0.02770  222 LEU A N   
1944 C CA  . LEU A 222 ? 0.37098 0.27161 0.26020 0.05279  0.07511  -0.01860 222 LEU A CA  
1945 C C   . LEU A 222 ? 0.30771 0.30037 0.31108 0.06536  0.00865  -0.04239 222 LEU A C   
1946 O O   . LEU A 222 ? 0.27751 0.36236 0.31977 -0.00138 0.01758  -0.02266 222 LEU A O   
1947 C CB  . LEU A 222 ? 0.43584 0.35523 0.28555 -0.02460 0.05021  -0.02936 222 LEU A CB  
1948 C CG  . LEU A 222 ? 0.28757 0.29892 0.29093 -0.02469 0.04744  0.01713  222 LEU A CG  
1949 C CD1 . LEU A 222 ? 0.33584 0.32988 0.30265 -0.03091 -0.02323 -0.03425 222 LEU A CD1 
1950 C CD2 . LEU A 222 ? 0.27531 0.31992 0.29998 -0.04969 0.08939  -0.01455 222 LEU A CD2 
1951 N N   . PHE A 223 ? 0.30975 0.36842 0.28402 -0.01469 0.04006  -0.01596 223 PHE A N   
1952 C CA  . PHE A 223 ? 0.35212 0.34337 0.28072 -0.02534 0.01665  -0.06866 223 PHE A CA  
1953 C C   . PHE A 223 ? 0.36915 0.38972 0.30739 -0.02908 0.01152  -0.06176 223 PHE A C   
1954 O O   . PHE A 223 ? 0.34384 0.41272 0.29667 0.00365  -0.00239 -0.01589 223 PHE A O   
1955 C CB  . PHE A 223 ? 0.29440 0.37335 0.29824 -0.04041 0.01548  -0.00097 223 PHE A CB  
1956 C CG  . PHE A 223 ? 0.35927 0.33600 0.26241 -0.05353 0.01823  -0.01749 223 PHE A CG  
1957 C CD1 . PHE A 223 ? 0.34602 0.34594 0.29920 -0.08210 0.03043  -0.00477 223 PHE A CD1 
1958 C CD2 . PHE A 223 ? 0.30779 0.28968 0.24774 -0.00739 0.04450  -0.08248 223 PHE A CD2 
1959 C CE1 . PHE A 223 ? 0.30996 0.31630 0.32950 -0.03365 0.00995  0.00154  223 PHE A CE1 
1960 C CE2 . PHE A 223 ? 0.32824 0.26514 0.25299 -0.01055 -0.00741 -0.04374 223 PHE A CE2 
1961 C CZ  . PHE A 223 ? 0.28274 0.32587 0.30349 -0.04038 -0.04129 -0.01447 223 PHE A CZ  
1962 N N   . PRO A 224 ? 0.29725 0.38107 0.32232 -0.07000 0.03824  -0.05316 224 PRO A N   
1963 C CA  . PRO A 224 ? 0.38903 0.34461 0.30761 -0.04759 0.06292  -0.07825 224 PRO A CA  
1964 C C   . PRO A 224 ? 0.39159 0.34326 0.29670 -0.02707 0.04450  -0.06513 224 PRO A C   
1965 O O   . PRO A 224 ? 0.41370 0.37697 0.33447 0.01376  0.05543  -0.03275 224 PRO A O   
1966 C CB  . PRO A 224 ? 0.41866 0.35174 0.32064 -0.06766 0.02353  -0.03547 224 PRO A CB  
1967 C CG  . PRO A 224 ? 0.41736 0.33500 0.31921 -0.02857 0.07580  -0.03206 224 PRO A CG  
1968 C CD  . PRO A 224 ? 0.33159 0.31117 0.34942 -0.08213 0.05854  -0.00786 224 PRO A CD  
1969 N N   . GLY A 225 ? 0.38700 0.33578 0.31570 -0.11548 0.02171  -0.01119 225 GLY A N   
1970 C CA  . GLY A 225 ? 0.41089 0.28637 0.30417 -0.06168 0.00355  -0.07011 225 GLY A CA  
1971 C C   . GLY A 225 ? 0.43712 0.35031 0.34461 -0.03034 0.05758  -0.04558 225 GLY A C   
1972 O O   . GLY A 225 ? 0.44232 0.34424 0.32730 -0.00367 0.07360  -0.00415 225 GLY A O   
1973 N N   . THR A 226 ? 0.37717 0.33431 0.33313 -0.09433 0.04237  -0.04379 226 THR A N   
1974 C CA  . THR A 226 ? 0.41918 0.33966 0.33188 -0.05455 0.03368  -0.06412 226 THR A CA  
1975 C C   . THR A 226 ? 0.46154 0.34983 0.29950 -0.01223 0.03795  -0.02365 226 THR A C   
1976 O O   . THR A 226 ? 0.46324 0.42190 0.28855 0.00587  0.06622  -0.00084 226 THR A O   
1977 C CB  . THR A 226 ? 0.60676 0.37227 0.40392 -0.02900 0.03121  -0.05502 226 THR A CB  
1978 O OG1 . THR A 226 ? 0.62863 0.34877 0.37182 0.03708  0.07250  -0.01440 226 THR A OG1 
1979 C CG2 . THR A 226 ? 0.55621 0.36652 0.43902 -0.02928 0.10605  -0.11632 226 THR A CG2 
1980 N N   . ASP A 227 ? 0.49427 0.27336 0.34641 0.06705  0.02218  0.00084  227 ASP A N   
1981 C CA  . ASP A 227 ? 0.45342 0.27320 0.34104 -0.01281 0.02473  -0.03176 227 ASP A CA  
1982 C C   . ASP A 227 ? 0.42923 0.32611 0.34130 -0.01624 0.02436  -0.00893 227 ASP A C   
1983 O O   . ASP A 227 ? 0.38562 0.34780 0.38806 -0.06363 0.03266  0.00535  227 ASP A O   
1984 C CB  . ASP A 227 ? 0.47213 0.29609 0.38506 0.04567  -0.00434 0.00264  227 ASP A CB  
1985 C CG  . ASP A 227 ? 0.59882 0.40453 0.41615 0.08226  0.08582  -0.01223 227 ASP A CG  
1986 O OD1 . ASP A 227 ? 0.47467 0.37113 0.38163 -0.01455 0.00234  -0.04758 227 ASP A OD1 
1987 O OD2 . ASP A 227 ? 0.69829 0.46777 0.47999 0.09816  0.05033  0.00458  227 ASP A OD2 
1988 N N   . HIS A 228 ? 0.39203 0.37276 0.34275 -0.02897 0.06429  0.03061  228 HIS A N   
1989 C CA  . HIS A 228 ? 0.31624 0.39539 0.32991 -0.04939 -0.00992 -0.00189 228 HIS A CA  
1990 C C   . HIS A 228 ? 0.46411 0.36353 0.33637 -0.04013 -0.00603 -0.05826 228 HIS A C   
1991 O O   . HIS A 228 ? 0.45731 0.29731 0.33348 -0.08010 0.05861  -0.09102 228 HIS A O   
1992 C CB  . HIS A 228 ? 0.40246 0.40409 0.37536 -0.12068 -0.02332 -0.03107 228 HIS A CB  
1993 C CG  . HIS A 228 ? 0.44699 0.42479 0.36837 -0.07657 0.00097  -0.04172 228 HIS A CG  
1994 N ND1 . HIS A 228 ? 0.55159 0.41054 0.38505 -0.14187 0.00888  0.01433  228 HIS A ND1 
1995 C CD2 . HIS A 228 ? 0.46468 0.43073 0.37914 -0.06926 -0.02404 -0.04723 228 HIS A CD2 
1996 C CE1 . HIS A 228 ? 0.62726 0.42630 0.37775 -0.06568 0.05417  -0.01181 228 HIS A CE1 
1997 N NE2 . HIS A 228 ? 0.46912 0.41743 0.39533 -0.08055 -0.01133 -0.01474 228 HIS A NE2 
1998 N N   . ILE A 229 ? 0.39889 0.34049 0.36602 -0.03186 0.01677  -0.00642 229 ILE A N   
1999 C CA  . ILE A 229 ? 0.42939 0.32891 0.38813 -0.02760 -0.01266 0.04833  229 ILE A CA  
2000 C C   . ILE A 229 ? 0.41932 0.37246 0.31862 0.00751  0.00278  -0.02713 229 ILE A C   
2001 O O   . ILE A 229 ? 0.44096 0.37783 0.27821 -0.02573 -0.01251 -0.00113 229 ILE A O   
2002 C CB  . ILE A 229 ? 0.48482 0.41160 0.44413 -0.08168 -0.10874 0.03372  229 ILE A CB  
2003 C CG1 . ILE A 229 ? 0.57216 0.44905 0.45128 -0.11948 -0.10948 0.06184  229 ILE A CG1 
2004 C CG2 . ILE A 229 ? 0.44607 0.44176 0.44688 0.01211  -0.11679 -0.06401 229 ILE A CG2 
2005 C CD1 . ILE A 229 ? 0.55779 0.45589 0.46011 -0.17328 -0.04485 0.04743  229 ILE A CD1 
2006 N N   . ASP A 230 ? 0.39739 0.37937 0.35748 -0.01401 -0.01490 -0.05486 230 ASP A N   
2007 C CA  . ASP A 230 ? 0.34685 0.31189 0.31242 0.00944  0.07798  -0.03263 230 ASP A CA  
2008 C C   . ASP A 230 ? 0.26594 0.36342 0.29727 -0.00361 -0.05589 -0.01097 230 ASP A C   
2009 O O   . ASP A 230 ? 0.35030 0.35173 0.34907 -0.01506 -0.01413 -0.00357 230 ASP A O   
2010 C CB  . ASP A 230 ? 0.40000 0.34690 0.35704 0.01799  0.06698  0.02659  230 ASP A CB  
2011 C CG  . ASP A 230 ? 0.45649 0.37960 0.37928 0.02434  0.02121  0.01284  230 ASP A CG  
2012 O OD1 . ASP A 230 ? 0.42359 0.38799 0.42567 0.02423  0.00715  0.02634  230 ASP A OD1 
2013 O OD2 . ASP A 230 ? 0.44331 0.39475 0.39089 0.02224  0.02087  -0.01064 230 ASP A OD2 
2014 N N   . GLN A 231 ? 0.29492 0.34808 0.29215 -0.04745 -0.02380 -0.04514 231 GLN A N   
2015 C CA  . GLN A 231 ? 0.35609 0.27444 0.29679 0.03487  0.01312  -0.00917 231 GLN A CA  
2016 C C   . GLN A 231 ? 0.41078 0.28753 0.26339 -0.04337 -0.01930 -0.02595 231 GLN A C   
2017 O O   . GLN A 231 ? 0.36566 0.27762 0.27482 -0.04967 -0.02859 -0.04310 231 GLN A O   
2018 C CB  . GLN A 231 ? 0.38126 0.22333 0.29058 0.08452  0.03254  0.01029  231 GLN A CB  
2019 C CG  . GLN A 231 ? 0.34376 0.23850 0.32278 0.01204  0.03694  -0.00277 231 GLN A CG  
2020 C CD  . GLN A 231 ? 0.50100 0.31791 0.30864 -0.01653 0.01843  -0.04641 231 GLN A CD  
2021 O OE1 . GLN A 231 ? 0.43765 0.38584 0.28274 0.02461  0.05759  -0.03597 231 GLN A OE1 
2022 N NE2 . GLN A 231 ? 0.52208 0.25576 0.37039 -0.06551 -0.06082 -0.04717 231 GLN A NE2 
2023 N N   . LEU A 232 ? 0.40260 0.31250 0.27465 -0.01643 -0.01421 0.00649  232 LEU A N   
2024 C CA  . LEU A 232 ? 0.34192 0.32309 0.28229 -0.02245 -0.04568 0.02331  232 LEU A CA  
2025 C C   . LEU A 232 ? 0.42585 0.30685 0.33967 -0.02035 -0.02230 -0.03217 232 LEU A C   
2026 O O   . LEU A 232 ? 0.42860 0.28669 0.30359 0.02125  0.01598  0.00887  232 LEU A O   
2027 C CB  . LEU A 232 ? 0.47293 0.32378 0.27829 -0.08194 0.01615  0.02921  232 LEU A CB  
2028 C CG  . LEU A 232 ? 0.39602 0.33388 0.27781 -0.01808 0.05290  -0.01575 232 LEU A CG  
2029 C CD1 . LEU A 232 ? 0.46009 0.34731 0.30545 0.01925  0.07123  -0.01444 232 LEU A CD1 
2030 C CD2 . LEU A 232 ? 0.49150 0.31697 0.32411 -0.01782 0.03699  0.01383  232 LEU A CD2 
2031 N N   . LYS A 233 ? 0.36504 0.34355 0.38363 0.01184  -0.03293 -0.00088 233 LYS A N   
2032 C CA  . LYS A 233 ? 0.32572 0.34644 0.39116 0.01185  0.00948  -0.01528 233 LYS A CA  
2033 C C   . LYS A 233 ? 0.40422 0.30951 0.37798 -0.01377 -0.00191 -0.02201 233 LYS A C   
2034 O O   . LYS A 233 ? 0.44859 0.34133 0.39503 0.00415  -0.00742 -0.09069 233 LYS A O   
2035 C CB  . LYS A 233 ? 0.43927 0.32521 0.40038 -0.12666 -0.03793 -0.07056 233 LYS A CB  
2036 C CG  . LYS A 233 ? 0.39150 0.28201 0.42665 -0.01703 -0.00339 -0.06697 233 LYS A CG  
2037 C CD  . LYS A 233 ? 0.42638 0.30924 0.45928 -0.00994 -0.04599 -0.07360 233 LYS A CD  
2038 C CE  . LYS A 233 ? 0.47143 0.37090 0.47983 -0.01225 -0.04518 -0.10361 233 LYS A CE  
2039 N NZ  . LYS A 233 ? 0.47779 0.34866 0.50482 0.02343  -0.04940 -0.08214 233 LYS A NZ  
2040 N N   . LEU A 234 ? 0.35062 0.29700 0.34654 0.05910  -0.00005 -0.03250 234 LEU A N   
2041 C CA  . LEU A 234 ? 0.36874 0.27107 0.30381 -0.00899 -0.01917 -0.01392 234 LEU A CA  
2042 C C   . LEU A 234 ? 0.41267 0.33819 0.34316 0.00626  -0.02292 -0.01280 234 LEU A C   
2043 O O   . LEU A 234 ? 0.29259 0.35626 0.34638 -0.00070 0.01878  -0.00483 234 LEU A O   
2044 C CB  . LEU A 234 ? 0.28590 0.34058 0.31313 -0.00808 0.03424  -0.00436 234 LEU A CB  
2045 C CG  . LEU A 234 ? 0.31314 0.34419 0.31509 0.01755  0.07686  -0.00711 234 LEU A CG  
2046 C CD1 . LEU A 234 ? 0.45205 0.39590 0.25875 -0.04403 0.03914  0.02224  234 LEU A CD1 
2047 C CD2 . LEU A 234 ? 0.38569 0.39425 0.40055 0.02634  0.08427  -0.00359 234 LEU A CD2 
2048 N N   . ILE A 235 ? 0.31779 0.29437 0.30642 -0.01842 -0.02161 0.03449  235 ILE A N   
2049 C CA  . ILE A 235 ? 0.34543 0.37695 0.30294 0.05500  0.01425  -0.01692 235 ILE A CA  
2050 C C   . ILE A 235 ? 0.35283 0.30021 0.29287 -0.01565 0.02101  -0.00710 235 ILE A C   
2051 O O   . ILE A 235 ? 0.34147 0.32491 0.29004 -0.01557 0.00303  -0.03885 235 ILE A O   
2052 C CB  . ILE A 235 ? 0.28317 0.38747 0.26448 0.04476  -0.00367 0.02755  235 ILE A CB  
2053 C CG1 . ILE A 235 ? 0.29057 0.32601 0.29278 -0.01255 -0.06096 0.00797  235 ILE A CG1 
2054 C CG2 . ILE A 235 ? 0.28641 0.36872 0.28086 -0.00970 0.02985  -0.03933 235 ILE A CG2 
2055 C CD1 . ILE A 235 ? 0.29195 0.39337 0.28652 -0.06564 -0.05451 -0.03903 235 ILE A CD1 
2056 N N   . LEU A 236 ? 0.32481 0.32239 0.34049 -0.00772 -0.05449 -0.00079 236 LEU A N   
2057 C CA  . LEU A 236 ? 0.33712 0.31866 0.32091 -0.03226 -0.04328 -0.03091 236 LEU A CA  
2058 C C   . LEU A 236 ? 0.43436 0.36265 0.34239 -0.00555 -0.02792 -0.05835 236 LEU A C   
2059 O O   . LEU A 236 ? 0.37244 0.39396 0.34072 0.03021  -0.04568 -0.03181 236 LEU A O   
2060 C CB  . LEU A 236 ? 0.33833 0.33711 0.35198 -0.05191 -0.01542 -0.02353 236 LEU A CB  
2061 C CG  . LEU A 236 ? 0.36794 0.39369 0.35803 -0.08992 0.04803  -0.03616 236 LEU A CG  
2062 C CD1 . LEU A 236 ? 0.49689 0.36112 0.35744 -0.07304 0.03209  -0.04552 236 LEU A CD1 
2063 C CD2 . LEU A 236 ? 0.32152 0.45405 0.36450 -0.02951 0.06036  -0.01686 236 LEU A CD2 
2064 N N   . ARG A 237 ? 0.32093 0.35143 0.35889 0.00920  -0.02491 -0.01805 237 ARG A N   
2065 C CA  . ARG A 237 ? 0.25805 0.34880 0.40752 0.01150  -0.00609 -0.08355 237 ARG A CA  
2066 C C   . ARG A 237 ? 0.38891 0.38230 0.40062 -0.03237 -0.02917 -0.09380 237 ARG A C   
2067 O O   . ARG A 237 ? 0.34405 0.40751 0.38548 -0.01709 -0.01853 -0.05248 237 ARG A O   
2068 C CB  . ARG A 237 ? 0.17044 0.48474 0.47396 0.02540  0.05511  -0.08947 237 ARG A CB  
2069 C CG  . ARG A 237 ? 0.35960 0.60720 0.54136 -0.02956 0.18426  -0.08551 237 ARG A CG  
2070 C CD  . ARG A 237 ? 0.79337 0.77273 0.63111 0.00778  0.14116  -0.05523 237 ARG A CD  
2071 N NE  . ARG A 237 ? 1.02077 0.91353 0.70670 -0.04216 0.15887  -0.05409 237 ARG A NE  
2072 C CZ  . ARG A 237 ? 0.95685 0.99914 0.74464 -0.08929 0.07580  -0.03327 237 ARG A CZ  
2073 N NH1 . ARG A 237 ? 1.07884 1.07520 0.78430 -0.06939 0.04262  -0.02301 237 ARG A NH1 
2074 N NH2 . ARG A 237 ? 0.74245 1.01744 0.74399 -0.12621 0.01316  -0.00333 237 ARG A NH2 
2075 N N   . LEU A 238 ? 0.32050 0.30236 0.38409 -0.02465 -0.03018 -0.02059 238 LEU A N   
2076 C CA  . LEU A 238 ? 0.35547 0.28112 0.36338 -0.01793 0.06692  -0.02827 238 LEU A CA  
2077 C C   . LEU A 238 ? 0.32486 0.33692 0.36066 -0.01458 0.00458  -0.01214 238 LEU A C   
2078 O O   . LEU A 238 ? 0.38157 0.33031 0.35759 -0.02798 -0.03633 -0.01586 238 LEU A O   
2079 C CB  . LEU A 238 ? 0.46008 0.28859 0.32981 -0.04888 0.02278  -0.05055 238 LEU A CB  
2080 C CG  . LEU A 238 ? 0.32676 0.32702 0.33926 0.01883  -0.04501 -0.02617 238 LEU A CG  
2081 C CD1 . LEU A 238 ? 0.36426 0.30368 0.36971 -0.03934 0.01346  -0.05041 238 LEU A CD1 
2082 C CD2 . LEU A 238 ? 0.38016 0.34433 0.34274 0.05273  -0.07633 0.01344  238 LEU A CD2 
2083 N N   . VAL A 239 ? 0.31345 0.33087 0.34505 -0.05283 -0.00166 0.02217  239 VAL A N   
2084 C CA  . VAL A 239 ? 0.33750 0.35077 0.35547 -0.05341 0.03160  0.02772  239 VAL A CA  
2085 C C   . VAL A 239 ? 0.38389 0.35452 0.34395 -0.06043 -0.01252 -0.00967 239 VAL A C   
2086 O O   . VAL A 239 ? 0.47591 0.36500 0.36367 -0.02892 -0.01320 -0.01385 239 VAL A O   
2087 C CB  . VAL A 239 ? 0.31851 0.29633 0.37065 0.05144  -0.00522 0.00316  239 VAL A CB  
2088 C CG1 . VAL A 239 ? 0.34308 0.32040 0.34591 0.06155  -0.01967 0.02375  239 VAL A CG1 
2089 C CG2 . VAL A 239 ? 0.33364 0.31486 0.36358 -0.04183 0.00255  -0.06494 239 VAL A CG2 
2090 N N   . GLY A 240 ? 0.38513 0.33968 0.33895 -0.02743 -0.00994 -0.05024 240 GLY A N   
2091 C CA  . GLY A 240 ? 0.39080 0.33854 0.36855 -0.07470 -0.03601 -0.00687 240 GLY A CA  
2092 C C   . GLY A 240 ? 0.41047 0.31228 0.38826 0.00839  -0.02869 -0.00319 240 GLY A C   
2093 O O   . GLY A 240 ? 0.43073 0.31489 0.40963 0.00630  -0.08441 -0.03163 240 GLY A O   
2094 N N   . THR A 241 ? 0.44761 0.26463 0.40367 -0.05679 -0.00139 -0.01364 241 THR A N   
2095 C CA  . THR A 241 ? 0.37778 0.29385 0.39794 0.02762  -0.02912 -0.04152 241 THR A CA  
2096 C C   . THR A 241 ? 0.44421 0.33330 0.39473 -0.02836 0.00524  -0.07642 241 THR A C   
2097 O O   . THR A 241 ? 0.50982 0.41480 0.40683 -0.09133 0.02562  -0.08317 241 THR A O   
2098 C CB  . THR A 241 ? 0.37131 0.37199 0.35832 0.08633  -0.01836 -0.07118 241 THR A CB  
2099 O OG1 . THR A 241 ? 0.49441 0.38142 0.34799 0.05924  -0.04781 -0.06718 241 THR A OG1 
2100 C CG2 . THR A 241 ? 0.47356 0.40463 0.32168 0.01369  0.01068  -0.06322 241 THR A CG2 
2101 N N   . PRO A 242 ? 0.37882 0.32830 0.44284 -0.04728 0.06827  -0.05107 242 PRO A N   
2102 C CA  . PRO A 242 ? 0.51054 0.42942 0.44283 0.00501  0.08651  -0.03181 242 PRO A CA  
2103 C C   . PRO A 242 ? 0.45229 0.46537 0.45951 0.02873  0.04859  -0.01448 242 PRO A C   
2104 O O   . PRO A 242 ? 0.46394 0.42876 0.44020 -0.01206 0.00402  0.00699  242 PRO A O   
2105 C CB  . PRO A 242 ? 0.45721 0.41707 0.42378 0.04435  0.00550  -0.04814 242 PRO A CB  
2106 C CG  . PRO A 242 ? 0.50958 0.43629 0.43286 0.12520  0.03662  -0.11149 242 PRO A CG  
2107 C CD  . PRO A 242 ? 0.44605 0.42486 0.43296 0.05730  -0.00162 -0.07581 242 PRO A CD  
2108 N N   . GLY A 243 ? 0.43359 0.56962 0.51942 -0.00294 0.08981  -0.00371 243 GLY A N   
2109 C CA  . GLY A 243 ? 0.43472 0.58023 0.52329 -0.05636 0.10234  0.07117  243 GLY A CA  
2110 C C   . GLY A 243 ? 0.60377 0.54684 0.55336 -0.00100 0.06473  0.08586  243 GLY A C   
2111 O O   . GLY A 243 ? 0.45708 0.48658 0.56987 0.05602  0.12209  0.07689  243 GLY A O   
2112 N N   . ALA A 244 ? 0.60457 0.62299 0.53193 0.00455  0.04884  0.10942  244 ALA A N   
2113 C CA  . ALA A 244 ? 0.61489 0.63079 0.53609 -0.03113 0.11680  0.12884  244 ALA A CA  
2114 C C   . ALA A 244 ? 0.65056 0.62134 0.53374 0.03386  0.18974  0.08457  244 ALA A C   
2115 O O   . ALA A 244 ? 0.62493 0.62325 0.56336 0.03818  0.15614  0.05899  244 ALA A O   
2116 C CB  . ALA A 244 ? 0.77089 0.63878 0.52959 -0.05942 0.09776  0.11621  244 ALA A CB  
2117 N N   . GLU A 245 ? 0.55018 0.55733 0.51115 0.04830  0.15689  0.02188  245 GLU A N   
2118 C CA  . GLU A 245 ? 0.68474 0.57639 0.51379 0.06631  0.12348  0.05032  245 GLU A CA  
2119 C C   . GLU A 245 ? 0.53812 0.52310 0.51338 -0.02585 0.13033  0.01056  245 GLU A C   
2120 O O   . GLU A 245 ? 0.63261 0.49704 0.50920 -0.03478 0.11727  0.01976  245 GLU A O   
2121 C CB  . GLU A 245 ? 0.83508 0.64681 0.56652 0.12479  0.16022  0.00775  245 GLU A CB  
2122 C CG  . GLU A 245 ? 0.86049 0.80867 0.64890 0.22471  0.09746  -0.03659 245 GLU A CG  
2123 C CD  . GLU A 245 ? 0.96235 0.93972 0.69999 0.20367  0.08506  -0.04589 245 GLU A CD  
2124 O OE1 . GLU A 245 ? 0.94309 0.99696 0.70071 0.23379  0.08375  -0.09131 245 GLU A OE1 
2125 O OE2 . GLU A 245 ? 0.97567 0.96186 0.71283 0.23094  0.07608  -0.01533 245 GLU A OE2 
2126 N N   . LEU A 246 ? 0.47068 0.47189 0.46661 -0.05588 0.11536  -0.00855 246 LEU A N   
2127 C CA  . LEU A 246 ? 0.49580 0.41921 0.48409 -0.08196 0.13134  0.01330  246 LEU A CA  
2128 C C   . LEU A 246 ? 0.49015 0.37754 0.52378 -0.09995 0.09844  -0.03185 246 LEU A C   
2129 O O   . LEU A 246 ? 0.50471 0.42402 0.54158 -0.09439 0.06096  0.01156  246 LEU A O   
2130 C CB  . LEU A 246 ? 0.52334 0.41711 0.45750 0.02793  0.10369  0.05055  246 LEU A CB  
2131 C CG  . LEU A 246 ? 0.40443 0.43307 0.45866 -0.06299 0.09447  0.06204  246 LEU A CG  
2132 C CD1 . LEU A 246 ? 0.37821 0.44086 0.47731 0.00512  -0.00888 -0.00096 246 LEU A CD1 
2133 C CD2 . LEU A 246 ? 0.53783 0.47763 0.46744 -0.08164 0.12146  0.08481  246 LEU A CD2 
2134 N N   . LEU A 247 ? 0.47102 0.33715 0.57833 -0.01219 0.01797  -0.07297 247 LEU A N   
2135 C CA  . LEU A 247 ? 0.39323 0.44736 0.60254 -0.03231 -0.01510 -0.04487 247 LEU A CA  
2136 C C   . LEU A 247 ? 0.41669 0.44324 0.61958 -0.06310 -0.05194 -0.05265 247 LEU A C   
2137 O O   . LEU A 247 ? 0.60182 0.40402 0.63084 -0.06867 -0.01085 -0.08612 247 LEU A O   
2138 C CB  . LEU A 247 ? 0.47582 0.59597 0.60131 0.03613  -0.02472 0.01749  247 LEU A CB  
2139 C CG  . LEU A 247 ? 0.51198 0.73197 0.59964 0.11836  -0.01467 0.03036  247 LEU A CG  
2140 C CD1 . LEU A 247 ? 0.58277 0.75398 0.61028 0.21602  0.00001  0.06168  247 LEU A CD1 
2141 C CD2 . LEU A 247 ? 0.53995 0.78922 0.61511 0.13060  0.04534  0.02184  247 LEU A CD2 
2142 N N   . LYS A 248 ? 0.46671 0.47988 0.61090 -0.08599 0.08421  -0.02594 248 LYS A N   
2143 C CA  . LYS A 248 ? 0.40227 0.51709 0.67491 -0.05606 0.01936  -0.01648 248 LYS A CA  
2144 C C   . LYS A 248 ? 0.41521 0.44709 0.70234 -0.15465 0.02926  -0.03867 248 LYS A C   
2145 O O   . LYS A 248 ? 0.56081 0.50976 0.75244 -0.16077 0.07652  -0.00367 248 LYS A O   
2146 C CB  . LYS A 248 ? 0.55616 0.63398 0.69182 -0.16013 0.00248  0.05727  248 LYS A CB  
2147 C CG  . LYS A 248 ? 0.79574 0.76367 0.76011 -0.05610 -0.06339 0.07260  248 LYS A CG  
2148 C CD  . LYS A 248 ? 0.87475 0.85357 0.78615 -0.05966 -0.03130 0.12897  248 LYS A CD  
2149 C CE  . LYS A 248 ? 0.93043 0.92266 0.80548 -0.10420 -0.04783 0.13659  248 LYS A CE  
2150 N NZ  . LYS A 248 ? 0.93313 0.92246 0.81093 -0.10693 -0.02366 0.15086  248 LYS A NZ  
2151 N N   . LYS A 249 ? 0.48330 0.38067 0.68025 -0.09922 0.06458  -0.01477 249 LYS A N   
2152 C CA  . LYS A 249 ? 0.49611 0.37468 0.68022 -0.07918 0.05896  -0.01246 249 LYS A CA  
2153 C C   . LYS A 249 ? 0.51872 0.44028 0.70094 -0.09017 0.03482  0.00300  249 LYS A C   
2154 O O   . LYS A 249 ? 0.49617 0.46198 0.73565 -0.02641 0.02104  -0.03205 249 LYS A O   
2155 C CB  . LYS A 249 ? 0.50091 0.33334 0.67010 -0.08864 0.07707  0.01162  249 LYS A CB  
2156 C CG  . LYS A 249 ? 0.59422 0.41603 0.64360 0.02152  0.11122  -0.00252 249 LYS A CG  
2157 C CD  . LYS A 249 ? 0.64241 0.42674 0.63461 0.10641  0.14006  0.01265  249 LYS A CD  
2158 C CE  . LYS A 249 ? 0.57352 0.45663 0.58828 0.08415  0.15399  0.05498  249 LYS A CE  
2159 N NZ  . LYS A 249 ? 0.47116 0.43839 0.57810 0.07672  0.17366  0.04401  249 LYS A NZ  
2160 N N   . ILE A 250 ? 0.43918 0.47397 0.68876 -0.05109 0.14178  -0.01781 250 ILE A N   
2161 C CA  . ILE A 250 ? 0.54380 0.50102 0.69064 -0.07458 0.04808  0.02355  250 ILE A CA  
2162 C C   . ILE A 250 ? 0.60442 0.53648 0.72548 -0.11961 0.00741  0.05453  250 ILE A C   
2163 O O   . ILE A 250 ? 0.62328 0.53688 0.70249 0.01546  0.01834  0.07778  250 ILE A O   
2164 C CB  . ILE A 250 ? 0.52907 0.49441 0.65943 -0.06270 0.07102  0.01382  250 ILE A CB  
2165 C CG1 . ILE A 250 ? 0.40265 0.43595 0.66545 -0.01498 0.05238  0.06432  250 ILE A CG1 
2166 C CG2 . ILE A 250 ? 0.59111 0.47719 0.65367 -0.02582 0.08397  -0.05162 250 ILE A CG2 
2167 C CD1 . ILE A 250 ? 0.36821 0.42077 0.66085 0.01571  0.06687  0.06811  250 ILE A CD1 
2168 N N   . SER A 251 ? 0.59373 0.60651 0.78067 -0.12240 -0.04328 0.06591  251 SER A N   
2169 C CA  . SER A 251 ? 0.67227 0.72663 0.81144 -0.08571 -0.09768 -0.01495 251 SER A CA  
2170 C C   . SER A 251 ? 0.82861 0.79720 0.76952 -0.12163 -0.02713 -0.05077 251 SER A C   
2171 O O   . SER A 251 ? 0.95737 0.85289 0.78767 -0.16873 0.01129  -0.07980 251 SER A O   
2172 C CB  . SER A 251 ? 0.68475 0.77472 0.86399 -0.07341 -0.10215 -0.05322 251 SER A CB  
2173 O OG  . SER A 251 ? 0.63146 0.78460 0.88734 -0.01527 -0.08357 -0.08797 251 SER A OG  
2174 N N   A SER A 252 ? 0.77235 0.78406 0.73609 -0.15721 -0.02973 -0.04032 252 SER A N   
2175 N N   B SER A 252 ? 0.77526 0.82393 0.73677 -0.13448 -0.01659 -0.05081 252 SER A N   
2176 C CA  A SER A 252 ? 0.71591 0.80399 0.70573 -0.14387 -0.04904 0.01131  252 SER A CA  
2177 C CA  B SER A 252 ? 0.72483 0.86965 0.70513 -0.11536 -0.01919 -0.02125 252 SER A CA  
2178 C C   A SER A 252 ? 0.76450 0.81259 0.69355 -0.13844 -0.04970 0.01533  252 SER A C   
2179 C C   B SER A 252 ? 0.76379 0.84188 0.69330 -0.12857 -0.03727 0.00037  252 SER A C   
2180 O O   A SER A 252 ? 0.76027 0.82551 0.67933 -0.19491 -0.08340 -0.00660 252 SER A O   
2181 O O   B SER A 252 ? 0.76318 0.84704 0.68065 -0.17677 -0.07060 -0.01870 252 SER A O   
2182 C CB  A SER A 252 ? 0.63423 0.76517 0.67161 -0.13615 -0.05954 0.05839  252 SER A CB  
2183 C CB  B SER A 252 ? 0.66388 0.89120 0.67368 -0.09350 -0.01246 -0.02349 252 SER A CB  
2184 O OG  A SER A 252 ? 0.62588 0.72557 0.65976 -0.10313 -0.07617 0.09909  252 SER A OG  
2185 O OG  B SER A 252 ? 0.62692 0.91007 0.65805 -0.08263 -0.00833 -0.04015 252 SER A OG  
2186 N N   . GLU A 253 ? 0.77942 0.77091 0.69562 -0.17810 -0.03632 -0.00673 253 GLU A N   
2187 C CA  . GLU A 253 ? 0.85383 0.79420 0.70791 -0.13791 -0.01478 -0.05354 253 GLU A CA  
2188 C C   . GLU A 253 ? 0.90629 0.76104 0.62690 -0.19028 -0.00400 -0.07283 253 GLU A C   
2189 O O   . GLU A 253 ? 0.94989 0.75807 0.60613 -0.24393 0.01412  -0.08316 253 GLU A O   
2190 C CB  . GLU A 253 ? 0.99448 0.86459 0.78945 -0.08822 -0.00231 -0.04921 253 GLU A CB  
2191 C CG  . GLU A 253 ? 1.11988 0.93789 0.85003 -0.03632 0.04770  -0.02873 253 GLU A CG  
2192 C CD  . GLU A 253 ? 1.24320 1.03283 0.89430 0.03830  0.07599  -0.04394 253 GLU A CD  
2193 O OE1 . GLU A 253 ? 1.25779 1.06584 0.91123 -0.01408 0.07609  -0.06987 253 GLU A OE1 
2194 O OE2 . GLU A 253 ? 1.29606 1.03167 0.90730 0.12498  0.09300  -0.04081 253 GLU A OE2 
2195 N N   . SER A 254 ? 0.90459 0.70915 0.60325 -0.25330 0.01073  -0.05915 254 SER A N   
2196 C CA  . SER A 254 ? 0.96472 0.69109 0.53743 -0.21810 0.07342  -0.07405 254 SER A CA  
2197 C C   . SER A 254 ? 0.78879 0.66586 0.51329 -0.15607 0.13414  -0.07745 254 SER A C   
2198 O O   . SER A 254 ? 0.80608 0.64024 0.52065 -0.18612 0.16036  -0.05876 254 SER A O   
2199 C CB  . SER A 254 ? 1.11613 0.70447 0.55842 -0.17637 0.10191  -0.05541 254 SER A CB  
2200 O OG  . SER A 254 ? 1.23854 0.75111 0.56715 -0.16952 0.05566  -0.09453 254 SER A OG  
2201 N N   . ALA A 255 ? 0.78192 0.69287 0.51125 -0.05233 0.03033  -0.08661 255 ALA A N   
2202 C CA  . ALA A 255 ? 0.66154 0.62231 0.51580 -0.07642 0.02975  -0.08443 255 ALA A CA  
2203 C C   . ALA A 255 ? 0.73973 0.59324 0.50163 -0.09209 0.09088  -0.09706 255 ALA A C   
2204 O O   . ALA A 255 ? 0.73744 0.57261 0.45334 -0.10614 0.12968  -0.10763 255 ALA A O   
2205 C CB  . ALA A 255 ? 0.54839 0.66076 0.52231 -0.08075 -0.01378 -0.06780 255 ALA A CB  
2206 N N   A ARG A 256 ? 0.73522 0.61456 0.56222 -0.09221 0.11062  -0.04714 256 ARG A N   
2207 N N   B ARG A 256 ? 0.72753 0.58182 0.48454 -0.13617 0.14550  -0.08457 256 ARG A N   
2208 C CA  A ARG A 256 ? 0.68746 0.62775 0.62485 -0.06803 0.10591  0.00300  256 ARG A CA  
2209 C CA  B ARG A 256 ? 0.70206 0.56904 0.49129 -0.14520 0.11948  -0.04405 256 ARG A CA  
2210 C C   A ARG A 256 ? 0.72819 0.65169 0.63251 -0.05725 0.08176  0.00759  256 ARG A C   
2211 C C   B ARG A 256 ? 0.66149 0.46953 0.43233 -0.10179 0.07553  -0.08646 256 ARG A C   
2212 O O   A ARG A 256 ? 0.82585 0.70894 0.66461 -0.08437 0.04198  0.01135  256 ARG A O   
2213 O O   B ARG A 256 ? 0.67559 0.41110 0.36114 -0.14910 0.08799  -0.15375 256 ARG A O   
2214 C CB  A ARG A 256 ? 0.62380 0.61631 0.67093 -0.04455 0.09383  0.02671  256 ARG A CB  
2215 C CB  B ARG A 256 ? 0.66746 0.62579 0.55095 -0.10677 0.15301  0.01067  256 ARG A CB  
2216 C CG  A ARG A 256 ? 0.48321 0.55054 0.71565 0.01940  0.10445  0.03676  256 ARG A CG  
2217 C CG  B ARG A 256 ? 0.67050 0.61045 0.61106 -0.06626 0.18133  0.02691  256 ARG A CG  
2218 C CD  A ARG A 256 ? 0.58759 0.53115 0.76600 0.00661  0.02653  0.09106  256 ARG A CD  
2219 C CD  B ARG A 256 ? 0.69380 0.60239 0.66160 -0.10194 0.15088  0.06614  256 ARG A CD  
2220 N NE  A ARG A 256 ? 0.70453 0.56604 0.81280 -0.03735 -0.00888 0.11827  256 ARG A NE  
2221 N NE  B ARG A 256 ? 0.75152 0.66142 0.72245 -0.01796 0.15010  0.08970  256 ARG A NE  
2222 C CZ  A ARG A 256 ? 0.78166 0.63609 0.86166 -0.03649 -0.00891 0.13635  256 ARG A CZ  
2223 C CZ  B ARG A 256 ? 0.76624 0.70574 0.75697 -0.01874 0.16891  0.12067  256 ARG A CZ  
2224 N NH1 A ARG A 256 ? 0.86735 0.62604 0.86314 -0.02256 -0.00508 0.17093  256 ARG A NH1 
2225 N NH1 B ARG A 256 ? 0.71083 0.69662 0.76681 -0.05489 0.14120  0.12412  256 ARG A NH1 
2226 N NH2 A ARG A 256 ? 0.74107 0.69144 0.89035 -0.06127 -0.00984 0.12817  256 ARG A NH2 
2227 N NH2 B ARG A 256 ? 0.82767 0.70768 0.75741 -0.04479 0.19118  0.15428  256 ARG A NH2 
2228 N N   A ASN A 257 ? 0.68204 0.62253 0.62094 -0.01555 0.07868  -0.00502 257 ASN A N   
2229 N N   B ASN A 257 ? 0.65816 0.50869 0.44794 -0.11386 -0.01391 -0.08602 257 ASN A N   
2230 C CA  A ASN A 257 ? 0.70653 0.57856 0.59647 -0.07010 0.05560  -0.03460 257 ASN A CA  
2231 C CA  B ASN A 257 ? 0.70127 0.53125 0.50869 -0.08033 0.02019  -0.11231 257 ASN A CA  
2232 C C   A ASN A 257 ? 0.67979 0.50685 0.52187 -0.09116 0.06262  -0.09038 257 ASN A C   
2233 C C   B ASN A 257 ? 0.68881 0.50409 0.49239 -0.09192 0.05586  -0.09951 257 ASN A C   
2234 O O   A ASN A 257 ? 0.76010 0.48860 0.48384 -0.08932 0.02303  -0.12612 257 ASN A O   
2235 O O   B ASN A 257 ? 0.77764 0.52815 0.48200 -0.05797 0.04466  -0.07503 257 ASN A O   
2236 C CB  A ASN A 257 ? 0.66587 0.56020 0.62258 -0.09439 0.03254  0.03427  257 ASN A CB  
2237 C CB  B ASN A 257 ? 0.71448 0.57312 0.56082 -0.06890 0.05016  -0.08076 257 ASN A CB  
2238 C CG  A ASN A 257 ? 0.59231 0.47807 0.63479 -0.05021 0.01182  0.08380  257 ASN A CG  
2239 C CG  B ASN A 257 ? 0.70482 0.57394 0.59886 0.01209  0.11086  -0.05615 257 ASN A CG  
2240 O OD1 A ASN A 257 ? 0.60225 0.46917 0.63882 -0.08220 0.02780  0.07033  257 ASN A OD1 
2241 O OD1 B ASN A 257 ? 0.81185 0.58140 0.64463 0.02109  0.15747  -0.02078 257 ASN A OD1 
2242 N ND2 A ASN A 257 ? 0.62050 0.48605 0.63168 0.02406  -0.01180 0.10557  257 ASN A ND2 
2243 N ND2 B ASN A 257 ? 0.72179 0.61219 0.59123 -0.05822 0.14014  -0.06820 257 ASN A ND2 
2244 N N   . TYR A 258 ? 0.65099 0.46057 0.49049 -0.10598 0.08861  -0.10799 258 TYR A N   
2245 C CA  . TYR A 258 ? 0.73890 0.40269 0.43587 -0.12014 0.06168  -0.12259 258 TYR A CA  
2246 C C   . TYR A 258 ? 0.73759 0.40082 0.43570 -0.10295 0.05695  -0.09677 258 TYR A C   
2247 O O   . TYR A 258 ? 0.83098 0.35684 0.44819 -0.06023 0.06727  -0.08071 258 TYR A O   
2248 C CB  . TYR A 258 ? 0.72791 0.41534 0.41669 -0.05806 0.03731  -0.12067 258 TYR A CB  
2249 C CG  . TYR A 258 ? 0.66668 0.40243 0.40946 -0.02918 0.00680  -0.09448 258 TYR A CG  
2250 C CD1 . TYR A 258 ? 0.70339 0.38345 0.39900 0.00309  -0.03019 -0.08359 258 TYR A CD1 
2251 C CD2 . TYR A 258 ? 0.73675 0.43855 0.40050 0.01033  0.01116  -0.09388 258 TYR A CD2 
2252 C CE1 . TYR A 258 ? 0.77139 0.37351 0.36781 0.03142  -0.01462 -0.07132 258 TYR A CE1 
2253 C CE2 . TYR A 258 ? 0.72015 0.44510 0.37520 0.03630  0.06900  -0.07993 258 TYR A CE2 
2254 C CZ  . TYR A 258 ? 0.73840 0.39430 0.36735 0.04037  0.01900  -0.04379 258 TYR A CZ  
2255 O OH  . TYR A 258 ? 0.66503 0.34277 0.37970 0.00293  -0.03190 -0.02632 258 TYR A OH  
2256 N N   A ILE A 259 ? 0.67592 0.45616 0.40791 -0.05209 0.04610  -0.12486 259 ILE A N   
2257 N N   B ILE A 259 ? 0.65703 0.44095 0.44676 -0.05676 0.07577  -0.10814 259 ILE A N   
2258 C CA  A ILE A 259 ? 0.58235 0.50398 0.42987 -0.04604 0.04993  -0.13319 259 ILE A CA  
2259 C CA  B ILE A 259 ? 0.56842 0.47928 0.45101 -0.04686 0.09481  -0.09469 259 ILE A CA  
2260 C C   A ILE A 259 ? 0.62366 0.55704 0.42024 -0.11002 0.03913  -0.10728 259 ILE A C   
2261 C C   B ILE A 259 ? 0.59674 0.51947 0.44565 -0.05709 0.09231  -0.12313 259 ILE A C   
2262 O O   A ILE A 259 ? 0.67965 0.59007 0.39378 -0.02900 0.02152  -0.08881 259 ILE A O   
2263 O O   B ILE A 259 ? 0.58874 0.50071 0.42655 -0.00536 0.09274  -0.18050 259 ILE A O   
2264 C CB  A ILE A 259 ? 0.65926 0.56613 0.44632 -0.02214 0.03207  -0.13958 259 ILE A CB  
2265 C CB  B ILE A 259 ? 0.54572 0.51731 0.46017 -0.06821 0.10371  -0.04499 259 ILE A CB  
2266 C CG1 A ILE A 259 ? 0.66200 0.55514 0.47045 0.04536  0.05550  -0.10010 259 ILE A CG1 
2267 C CG1 B ILE A 259 ? 0.44961 0.52308 0.48344 -0.11878 0.07967  0.01256  259 ILE A CG1 
2268 C CG2 A ILE A 259 ? 0.69063 0.60830 0.46297 0.00866  0.01548  -0.08634 259 ILE A CG2 
2269 C CG2 B ILE A 259 ? 0.52356 0.55709 0.45862 -0.09794 0.17068  -0.02366 259 ILE A CG2 
2270 C CD1 A ILE A 259 ? 0.54739 0.56588 0.49775 -0.05214 0.02433  -0.07447 259 ILE A CD1 
2271 C CD1 B ILE A 259 ? 0.38737 0.53400 0.48957 -0.23338 0.05123  0.02064  259 ILE A CD1 
2272 N N   . GLN A 260 ? 0.69459 0.57703 0.47558 -0.08968 0.07921  -0.08181 260 GLN A N   
2273 C CA  . GLN A 260 ? 0.69055 0.60468 0.50931 -0.10919 0.05745  0.00718  260 GLN A CA  
2274 C C   . GLN A 260 ? 0.77339 0.55633 0.49747 -0.08415 -0.01451 -0.00063 260 GLN A C   
2275 O O   . GLN A 260 ? 0.92349 0.60053 0.49013 -0.06876 -0.03694 0.04951  260 GLN A O   
2276 C CB  . GLN A 260 ? 0.79101 0.72232 0.59086 -0.09317 0.09307  0.07128  260 GLN A CB  
2277 C CG  . GLN A 260 ? 0.89209 0.78518 0.65881 -0.05453 0.11561  0.14914  260 GLN A CG  
2278 C CD  . GLN A 260 ? 1.11727 0.89612 0.72409 -0.02743 0.14266  0.19080  260 GLN A CD  
2279 O OE1 . GLN A 260 ? 1.26122 0.96619 0.77578 -0.04380 0.16180  0.21279  260 GLN A OE1 
2280 N NE2 . GLN A 260 ? 1.10599 0.89632 0.71537 0.02199  0.14607  0.26062  260 GLN A NE2 
2281 N N   . SER A 261 ? 0.65674 0.47439 0.45887 -0.08573 0.00982  -0.03520 261 SER A N   
2282 C CA  . SER A 261 ? 0.71942 0.43027 0.44727 -0.04363 0.03188  -0.05241 261 SER A CA  
2283 C C   . SER A 261 ? 0.68438 0.36807 0.45018 -0.04864 -0.02949 -0.07558 261 SER A C   
2284 O O   . SER A 261 ? 0.74400 0.39844 0.49231 0.06009  -0.05511 -0.04169 261 SER A O   
2285 C CB  . SER A 261 ? 0.82534 0.42448 0.42051 -0.00542 0.02191  -0.05741 261 SER A CB  
2286 O OG  . SER A 261 ? 0.76951 0.43836 0.41795 -0.03295 0.01092  -0.08323 261 SER A OG  
2287 N N   . LEU A 262 ? 0.65204 0.36458 0.44391 0.04983  0.00758  -0.08098 262 LEU A N   
2288 C CA  . LEU A 262 ? 0.57878 0.46645 0.48525 0.00073  -0.02444 -0.07651 262 LEU A CA  
2289 C C   . LEU A 262 ? 0.51968 0.47891 0.47385 0.03815  -0.03888 -0.09241 262 LEU A C   
2290 O O   . LEU A 262 ? 0.57561 0.52929 0.42909 -0.00360 -0.00601 -0.05830 262 LEU A O   
2291 C CB  . LEU A 262 ? 0.56187 0.43382 0.48661 -0.04302 -0.03527 -0.03544 262 LEU A CB  
2292 C CG  . LEU A 262 ? 0.55337 0.45861 0.46911 0.02891  -0.00385 -0.03561 262 LEU A CG  
2293 C CD1 . LEU A 262 ? 0.60833 0.46700 0.50179 0.07279  -0.05755 0.01569  262 LEU A CD1 
2294 C CD2 . LEU A 262 ? 0.58068 0.46639 0.37934 0.01242  0.03349  -0.06799 262 LEU A CD2 
2295 N N   . THR A 263 ? 0.53735 0.46398 0.55325 0.16526  -0.05459 -0.08166 263 THR A N   
2296 C CA  . THR A 263 ? 0.47614 0.49509 0.59672 0.07218  -0.05264 -0.06442 263 THR A CA  
2297 C C   . THR A 263 ? 0.51016 0.45704 0.55142 0.04688  0.00291  -0.02536 263 THR A C   
2298 O O   . THR A 263 ? 0.48211 0.42099 0.55128 0.05410  0.06354  -0.03486 263 THR A O   
2299 C CB  . THR A 263 ? 0.56576 0.56981 0.69115 0.08428  -0.03200 -0.08425 263 THR A CB  
2300 O OG1 . THR A 263 ? 0.62814 0.65088 0.75886 0.09251  0.01705  -0.08234 263 THR A OG1 
2301 C CG2 . THR A 263 ? 0.48621 0.58354 0.70845 0.15832  -0.05666 -0.05930 263 THR A CG2 
2302 N N   . GLN A 264 ? 0.41884 0.42855 0.52845 0.05924  -0.05713 -0.00351 264 GLN A N   
2303 C CA  . GLN A 264 ? 0.38544 0.43945 0.52557 0.04028  0.00888  0.02834  264 GLN A CA  
2304 C C   . GLN A 264 ? 0.34117 0.44122 0.53004 0.01272  -0.00903 -0.01499 264 GLN A C   
2305 O O   . GLN A 264 ? 0.46657 0.50807 0.57787 0.02615  -0.04832 -0.00161 264 GLN A O   
2306 C CB  . GLN A 264 ? 0.52464 0.39617 0.52056 0.02964  0.05676  0.12354  264 GLN A CB  
2307 C CG  . GLN A 264 ? 0.67387 0.44928 0.57876 -0.03614 0.07489  0.09624  264 GLN A CG  
2308 C CD  . GLN A 264 ? 0.72339 0.43222 0.61204 -0.08853 -0.01826 0.10934  264 GLN A CD  
2309 O OE1 . GLN A 264 ? 0.83200 0.43905 0.64475 -0.14355 -0.02003 0.10309  264 GLN A OE1 
2310 N NE2 . GLN A 264 ? 0.69659 0.34757 0.60234 -0.06442 -0.09226 0.12010  264 GLN A NE2 
2311 N N   . MET A 265 ? 0.39176 0.34474 0.45754 0.01842  0.04553  -0.01828 265 MET A N   
2312 C CA  . MET A 265 ? 0.45554 0.41142 0.43016 -0.01549 -0.00666 -0.01376 265 MET A CA  
2313 C C   . MET A 265 ? 0.33372 0.37291 0.40421 0.01226  0.01709  -0.00436 265 MET A C   
2314 O O   . MET A 265 ? 0.41518 0.40167 0.39755 0.03256  0.02829  -0.00242 265 MET A O   
2315 C CB  . MET A 265 ? 0.48815 0.46892 0.43223 -0.00041 0.09196  -0.08239 265 MET A CB  
2316 C CG  . MET A 265 ? 0.60871 0.52808 0.46891 -0.02214 0.10066  -0.06781 265 MET A CG  
2317 S SD  . MET A 265 ? 0.61039 0.60426 0.54537 -0.04726 0.03540  -0.05909 265 MET A SD  
2318 C CE  . MET A 265 ? 0.50249 0.59966 0.54117 -0.10260 0.02407  -0.02121 265 MET A CE  
2319 N N   . PRO A 266 ? 0.37389 0.42113 0.41014 -0.02134 -0.10145 -0.00752 266 PRO A N   
2320 C CA  . PRO A 266 ? 0.41547 0.41199 0.39208 0.03163  -0.06213 0.03114  266 PRO A CA  
2321 C C   . PRO A 266 ? 0.48557 0.34306 0.38845 0.01799  -0.03771 -0.01040 266 PRO A C   
2322 O O   . PRO A 266 ? 0.49562 0.40038 0.35100 0.01135  -0.07450 -0.06233 266 PRO A O   
2323 C CB  . PRO A 266 ? 0.45782 0.45238 0.37328 -0.01264 -0.08191 0.02754  266 PRO A CB  
2324 C CG  . PRO A 266 ? 0.43064 0.47948 0.41312 -0.05507 -0.18327 -0.00171 266 PRO A CG  
2325 C CD  . PRO A 266 ? 0.37733 0.36969 0.46196 -0.02420 -0.19122 -0.01635 266 PRO A CD  
2326 N N   . LYS A 267 ? 0.39634 0.34396 0.38107 -0.00702 0.00282  -0.00291 267 LYS A N   
2327 C CA  . LYS A 267 ? 0.32632 0.30400 0.35461 -0.06453 -0.01027 -0.04113 267 LYS A CA  
2328 C C   . LYS A 267 ? 0.36978 0.37467 0.34102 -0.08029 -0.01607 0.02168  267 LYS A C   
2329 O O   . LYS A 267 ? 0.48971 0.34924 0.40781 0.00087  -0.12269 0.01612  267 LYS A O   
2330 C CB  . LYS A 267 ? 0.33474 0.30992 0.42576 -0.00189 0.06608  -0.00998 267 LYS A CB  
2331 C CG  . LYS A 267 ? 0.52377 0.30700 0.43917 0.00496  0.01912  -0.00621 267 LYS A CG  
2332 C CD  . LYS A 267 ? 0.75710 0.38282 0.42623 0.01473  0.05410  -0.06686 267 LYS A CD  
2333 C CE  . LYS A 267 ? 0.73270 0.44789 0.45068 -0.06179 0.04318  -0.04506 267 LYS A CE  
2334 N NZ  . LYS A 267 ? 0.66103 0.45415 0.45507 -0.05623 0.00956  -0.07108 267 LYS A NZ  
2335 N N   . MET A 268 ? 0.35308 0.34737 0.32451 -0.00338 0.01765  0.02141  268 MET A N   
2336 C CA  . MET A 268 ? 0.36396 0.40395 0.32846 -0.04291 0.08124  -0.00184 268 MET A CA  
2337 C C   . MET A 268 ? 0.31648 0.34096 0.33426 -0.07551 0.01658  -0.03786 268 MET A C   
2338 O O   . MET A 268 ? 0.37419 0.38658 0.35244 0.01674  0.00642  -0.01671 268 MET A O   
2339 C CB  . MET A 268 ? 0.32503 0.50196 0.35725 -0.00666 0.06640  -0.00087 268 MET A CB  
2340 C CG  . MET A 268 ? 0.33816 0.53100 0.37220 -0.08036 0.05520  0.00131  268 MET A CG  
2341 S SD  . MET A 268 ? 0.42911 0.61325 0.44169 -0.05964 0.02550  -0.00734 268 MET A SD  
2342 C CE  . MET A 268 ? 0.50240 0.69703 0.55178 -0.03160 0.02911  -0.00638 268 MET A CE  
2343 N N   . ASN A 269 ? 0.36044 0.27121 0.36905 -0.16350 -0.08306 -0.02154 269 ASN A N   
2344 C CA  . ASN A 269 ? 0.36995 0.27421 0.36976 -0.09072 -0.12085 -0.02600 269 ASN A CA  
2345 C C   . ASN A 269 ? 0.44280 0.32656 0.36876 -0.05499 -0.06638 0.00337  269 ASN A C   
2346 O O   . ASN A 269 ? 0.41666 0.33185 0.36513 -0.06081 -0.00878 0.02897  269 ASN A O   
2347 C CB  . ASN A 269 ? 0.47543 0.29612 0.35354 -0.06389 -0.03949 -0.05086 269 ASN A CB  
2348 C CG  . ASN A 269 ? 0.56755 0.39433 0.39385 -0.05937 -0.06229 -0.05015 269 ASN A CG  
2349 O OD1 . ASN A 269 ? 0.67638 0.43556 0.43169 -0.08203 -0.14938 -0.04628 269 ASN A OD1 
2350 N ND2 . ASN A 269 ? 0.50483 0.49869 0.38958 -0.02529 -0.08721 -0.03628 269 ASN A ND2 
2351 N N   . PHE A 270 ? 0.42016 0.31978 0.35830 0.00054  -0.06937 -0.01946 270 PHE A N   
2352 C CA  . PHE A 270 ? 0.39216 0.31008 0.35782 0.02233  -0.10473 -0.01438 270 PHE A CA  
2353 C C   . PHE A 270 ? 0.36578 0.33319 0.38301 -0.03176 -0.05802 0.00926  270 PHE A C   
2354 O O   . PHE A 270 ? 0.41137 0.32202 0.37905 -0.05203 -0.02991 0.04760  270 PHE A O   
2355 C CB  . PHE A 270 ? 0.34569 0.35209 0.33631 0.06913  -0.12021 -0.04241 270 PHE A CB  
2356 C CG  . PHE A 270 ? 0.41598 0.36608 0.34425 -0.01749 -0.05411 -0.02226 270 PHE A CG  
2357 C CD1 . PHE A 270 ? 0.38620 0.31730 0.34831 -0.04183 -0.01909 -0.03576 270 PHE A CD1 
2358 C CD2 . PHE A 270 ? 0.46501 0.41585 0.32966 -0.08033 -0.00168 -0.04169 270 PHE A CD2 
2359 C CE1 . PHE A 270 ? 0.45579 0.35224 0.35309 -0.02419 -0.05751 -0.00359 270 PHE A CE1 
2360 C CE2 . PHE A 270 ? 0.45449 0.37122 0.33847 -0.09782 0.02762  -0.02340 270 PHE A CE2 
2361 C CZ  . PHE A 270 ? 0.44794 0.36488 0.37357 -0.08934 0.03629  -0.03405 270 PHE A CZ  
2362 N N   . ALA A 271 ? 0.40156 0.34647 0.37457 -0.01121 -0.06389 -0.06033 271 ALA A N   
2363 C CA  . ALA A 271 ? 0.39222 0.38066 0.40782 -0.06088 -0.01634 -0.04930 271 ALA A CA  
2364 C C   . ALA A 271 ? 0.43467 0.36959 0.42146 -0.12321 0.01595  -0.00421 271 ALA A C   
2365 O O   . ALA A 271 ? 0.38456 0.34284 0.48162 -0.06873 0.05037  -0.01303 271 ALA A O   
2366 C CB  . ALA A 271 ? 0.35332 0.48669 0.40186 -0.06232 -0.09197 -0.10451 271 ALA A CB  
2367 N N   . ASN A 272 ? 0.37576 0.42579 0.38763 -0.05170 -0.02075 0.01544  272 ASN A N   
2368 C CA  . ASN A 272 ? 0.34167 0.43530 0.39793 -0.01797 0.00123  0.01675  272 ASN A CA  
2369 C C   . ASN A 272 ? 0.34621 0.40684 0.39608 -0.06306 0.01986  0.00922  272 ASN A C   
2370 O O   . ASN A 272 ? 0.35956 0.45962 0.40564 -0.07504 0.01758  0.01901  272 ASN A O   
2371 C CB  . ASN A 272 ? 0.41555 0.42520 0.39630 0.04108  -0.03145 0.01078  272 ASN A CB  
2372 C CG  . ASN A 272 ? 0.46936 0.43936 0.40350 0.01748  -0.02629 -0.01781 272 ASN A CG  
2373 O OD1 . ASN A 272 ? 0.51977 0.46405 0.37592 -0.00414 -0.06869 -0.04832 272 ASN A OD1 
2374 N ND2 . ASN A 272 ? 0.43781 0.45485 0.41919 -0.01156 -0.07322 0.02150  272 ASN A ND2 
2375 N N   . VAL A 273 ? 0.39277 0.37764 0.37982 -0.08144 -0.07522 -0.02679 273 VAL A N   
2376 C CA  . VAL A 273 ? 0.37422 0.39945 0.36305 -0.09841 -0.02699 0.00836  273 VAL A CA  
2377 C C   . VAL A 273 ? 0.33902 0.48222 0.35209 -0.05715 0.03789  0.04326  273 VAL A C   
2378 O O   . VAL A 273 ? 0.39969 0.50837 0.35912 -0.01705 0.05064  0.00932  273 VAL A O   
2379 C CB  . VAL A 273 ? 0.40588 0.42774 0.40968 -0.03995 -0.01512 0.00447  273 VAL A CB  
2380 C CG1 . VAL A 273 ? 0.39783 0.43221 0.39378 -0.08978 -0.06851 0.05505  273 VAL A CG1 
2381 C CG2 . VAL A 273 ? 0.49041 0.38551 0.39073 -0.02952 0.04843  -0.01386 273 VAL A CG2 
2382 N N   . PHE A 274 ? 0.36686 0.44235 0.37746 -0.03068 0.00893  0.01275  274 PHE A N   
2383 C CA  . PHE A 274 ? 0.29139 0.43285 0.40127 -0.08143 -0.03275 -0.00453 274 PHE A CA  
2384 C C   . PHE A 274 ? 0.24244 0.47497 0.38650 -0.13790 0.02763  -0.00385 274 PHE A C   
2385 O O   . PHE A 274 ? 0.37098 0.59522 0.39608 -0.02482 -0.01011 -0.04611 274 PHE A O   
2386 C CB  . PHE A 274 ? 0.34614 0.39897 0.37624 -0.07877 -0.01946 -0.01002 274 PHE A CB  
2387 C CG  . PHE A 274 ? 0.39808 0.43043 0.36379 -0.09402 -0.01715 0.01794  274 PHE A CG  
2388 C CD1 . PHE A 274 ? 0.56488 0.42987 0.34900 -0.02106 -0.04605 0.00559  274 PHE A CD1 
2389 C CD2 . PHE A 274 ? 0.30585 0.40890 0.36494 -0.04150 -0.04577 -0.01794 274 PHE A CD2 
2390 C CE1 . PHE A 274 ? 0.52946 0.45316 0.33301 -0.02086 -0.05559 0.00691  274 PHE A CE1 
2391 C CE2 . PHE A 274 ? 0.33533 0.41540 0.35581 -0.06172 -0.09816 -0.05858 274 PHE A CE2 
2392 C CZ  . PHE A 274 ? 0.48609 0.41902 0.34232 -0.02494 -0.09838 -0.00717 274 PHE A CZ  
2393 N N   . ILE A 275 ? 0.31467 0.44876 0.42991 -0.04867 0.06158  0.00906  275 ILE A N   
2394 C CA  . ILE A 275 ? 0.34598 0.44585 0.49992 -0.06008 0.05291  -0.00116 275 ILE A CA  
2395 C C   . ILE A 275 ? 0.39006 0.43493 0.52089 -0.03858 0.00478  -0.01034 275 ILE A C   
2396 O O   . ILE A 275 ? 0.34497 0.39846 0.54362 -0.06453 0.01843  0.03446  275 ILE A O   
2397 C CB  . ILE A 275 ? 0.37151 0.49711 0.54016 -0.03396 0.03706  0.05675  275 ILE A CB  
2398 C CG1 . ILE A 275 ? 0.47662 0.55743 0.60298 -0.03236 0.10896  0.07009  275 ILE A CG1 
2399 C CG2 . ILE A 275 ? 0.37640 0.55494 0.51227 -0.05286 -0.01749 0.10189  275 ILE A CG2 
2400 C CD1 . ILE A 275 ? 0.50938 0.61754 0.62373 0.00572  0.16804  0.10220  275 ILE A CD1 
2401 N N   . GLY A 276 ? 0.33001 0.48430 0.56345 -0.03057 -0.04779 -0.00645 276 GLY A N   
2402 C CA  . GLY A 276 ? 0.42676 0.49339 0.60311 -0.01354 -0.04303 -0.05984 276 GLY A CA  
2403 C C   . GLY A 276 ? 0.40631 0.53498 0.62445 -0.08112 -0.03478 -0.13313 276 GLY A C   
2404 O O   . GLY A 276 ? 0.52429 0.52759 0.67530 -0.08847 -0.02045 -0.15879 276 GLY A O   
2405 N N   . ALA A 277 ? 0.27831 0.56340 0.54442 -0.11668 -0.04681 -0.11805 277 ALA A N   
2406 C CA  . ALA A 277 ? 0.29478 0.52430 0.53290 -0.04362 -0.06962 -0.12820 277 ALA A CA  
2407 C C   . ALA A 277 ? 0.32248 0.47366 0.56671 0.00565  -0.05280 -0.13999 277 ALA A C   
2408 O O   . ALA A 277 ? 0.40607 0.49783 0.59671 -0.01740 -0.05651 -0.10191 277 ALA A O   
2409 C CB  . ALA A 277 ? 0.37893 0.51807 0.52459 -0.09871 -0.06283 -0.14451 277 ALA A CB  
2410 N N   . ASN A 278 ? 0.28140 0.46120 0.59850 -0.03145 0.04358  -0.10851 278 ASN A N   
2411 C CA  . ASN A 278 ? 0.41424 0.43230 0.56379 -0.05025 0.05376  -0.09562 278 ASN A CA  
2412 C C   . ASN A 278 ? 0.46700 0.44183 0.52979 -0.06338 0.00879  -0.06377 278 ASN A C   
2413 O O   . ASN A 278 ? 0.40281 0.46970 0.54496 -0.03062 -0.00288 -0.11283 278 ASN A O   
2414 C CB  . ASN A 278 ? 0.51044 0.39681 0.54841 -0.07334 0.01270  -0.10227 278 ASN A CB  
2415 C CG  . ASN A 278 ? 0.60567 0.43683 0.55513 -0.00940 -0.02724 -0.09572 278 ASN A CG  
2416 O OD1 . ASN A 278 ? 0.58434 0.49999 0.55518 -0.06219 -0.02203 -0.09612 278 ASN A OD1 
2417 N ND2 . ASN A 278 ? 0.55297 0.43392 0.56936 -0.08427 -0.07248 -0.09545 278 ASN A ND2 
2418 N N   . PRO A 279 ? 0.42752 0.43586 0.47443 -0.02940 -0.03041 -0.05487 279 PRO A N   
2419 C CA  . PRO A 279 ? 0.33895 0.41872 0.46711 -0.01624 -0.06291 -0.02373 279 PRO A CA  
2420 C C   . PRO A 279 ? 0.35191 0.52280 0.44441 0.00378  -0.02993 -0.07228 279 PRO A C   
2421 O O   . PRO A 279 ? 0.32783 0.57976 0.45420 0.03230  -0.04882 -0.13848 279 PRO A O   
2422 C CB  . PRO A 279 ? 0.37457 0.44391 0.47895 -0.09861 -0.09298 -0.02640 279 PRO A CB  
2423 C CG  . PRO A 279 ? 0.41731 0.45894 0.48777 -0.15513 -0.04258 -0.06461 279 PRO A CG  
2424 C CD  . PRO A 279 ? 0.43449 0.46848 0.47584 -0.06293 -0.10593 -0.08926 279 PRO A CD  
2425 N N   . LEU A 280 ? 0.28381 0.49535 0.41177 0.00795  -0.04305 -0.06964 280 LEU A N   
2426 C CA  . LEU A 280 ? 0.34367 0.50381 0.41526 0.02092  -0.00307 -0.08546 280 LEU A CA  
2427 C C   . LEU A 280 ? 0.41859 0.42673 0.41884 -0.02770 -0.01273 -0.11305 280 LEU A C   
2428 O O   . LEU A 280 ? 0.31551 0.38002 0.42363 -0.03046 -0.00273 -0.10334 280 LEU A O   
2429 C CB  . LEU A 280 ? 0.35040 0.46170 0.43501 0.06646  0.01405  -0.10905 280 LEU A CB  
2430 C CG  . LEU A 280 ? 0.43768 0.43420 0.44309 0.07592  -0.02250 -0.12347 280 LEU A CG  
2431 C CD1 . LEU A 280 ? 0.47382 0.42500 0.46312 0.14258  -0.04675 -0.14436 280 LEU A CD1 
2432 C CD2 . LEU A 280 ? 0.50491 0.53126 0.43368 0.11855  0.02390  -0.14310 280 LEU A CD2 
2433 N N   . ALA A 281 ? 0.38687 0.38651 0.39443 -0.03654 -0.06297 -0.12957 281 ALA A N   
2434 C CA  . ALA A 281 ? 0.45292 0.43031 0.40102 -0.03533 -0.00661 -0.10462 281 ALA A CA  
2435 C C   . ALA A 281 ? 0.32448 0.44524 0.38610 -0.09249 -0.05804 -0.11642 281 ALA A C   
2436 O O   . ALA A 281 ? 0.29195 0.46259 0.38797 -0.05939 -0.03263 -0.09186 281 ALA A O   
2437 C CB  . ALA A 281 ? 0.37952 0.43205 0.40552 -0.09327 -0.01929 -0.11266 281 ALA A CB  
2438 N N   . VAL A 282 ? 0.29021 0.44364 0.40654 0.00479  -0.04849 -0.09536 282 VAL A N   
2439 C CA  . VAL A 282 ? 0.31393 0.47136 0.44435 0.06912  -0.04641 -0.04206 282 VAL A CA  
2440 C C   . VAL A 282 ? 0.32632 0.49011 0.41156 0.03473  -0.03526 -0.03842 282 VAL A C   
2441 O O   . VAL A 282 ? 0.30394 0.46567 0.40719 0.02167  0.02706  -0.04780 282 VAL A O   
2442 C CB  . VAL A 282 ? 0.30056 0.47115 0.47820 0.00013  0.00251  -0.05452 282 VAL A CB  
2443 C CG1 . VAL A 282 ? 0.34518 0.54815 0.50934 -0.06283 -0.07779 -0.06415 282 VAL A CG1 
2444 C CG2 . VAL A 282 ? 0.38167 0.51933 0.45502 -0.08269 0.04076  -0.08940 282 VAL A CG2 
2445 N N   . ASP A 283 ? 0.30330 0.47293 0.34590 -0.03640 0.02557  -0.03800 283 ASP A N   
2446 C CA  . ASP A 283 ? 0.32622 0.48460 0.37745 -0.02034 0.01937  -0.04170 283 ASP A CA  
2447 C C   . ASP A 283 ? 0.28684 0.43308 0.35533 -0.00387 -0.04100 0.01293  283 ASP A C   
2448 O O   . ASP A 283 ? 0.38180 0.44272 0.34168 -0.03019 -0.01507 0.01066  283 ASP A O   
2449 C CB  . ASP A 283 ? 0.34093 0.52087 0.39879 0.05345  0.04406  -0.04968 283 ASP A CB  
2450 C CG  . ASP A 283 ? 0.42426 0.51454 0.40864 0.11657  0.03987  -0.04597 283 ASP A CG  
2451 O OD1 . ASP A 283 ? 0.41154 0.49577 0.46824 0.08440  -0.05013 -0.03314 283 ASP A OD1 
2452 O OD2 . ASP A 283 ? 0.38225 0.50808 0.41209 0.03820  0.02233  -0.10677 283 ASP A OD2 
2453 N N   . LEU A 284 ? 0.30326 0.45214 0.32852 0.05363  -0.04817 -0.02987 284 LEU A N   
2454 C CA  . LEU A 284 ? 0.28088 0.39884 0.33675 0.06000  -0.12329 -0.00584 284 LEU A CA  
2455 C C   . LEU A 284 ? 0.39098 0.46824 0.33692 0.00199  -0.03167 -0.03620 284 LEU A C   
2456 O O   . LEU A 284 ? 0.32280 0.47223 0.37008 0.00265  0.01628  -0.07512 284 LEU A O   
2457 C CB  . LEU A 284 ? 0.23202 0.44524 0.37571 0.06172  -0.05293 0.01883  284 LEU A CB  
2458 C CG  . LEU A 284 ? 0.22518 0.43030 0.36675 -0.01606 -0.04513 -0.01030 284 LEU A CG  
2459 C CD1 . LEU A 284 ? 0.26008 0.39565 0.40727 -0.04125 -0.01004 0.00962  284 LEU A CD1 
2460 C CD2 . LEU A 284 ? 0.43298 0.42726 0.33154 0.00843  -0.03225 -0.05764 284 LEU A CD2 
2461 N N   . LEU A 285 ? 0.36725 0.43071 0.31067 0.02058  0.02577  -0.11204 285 LEU A N   
2462 C CA  . LEU A 285 ? 0.33796 0.38581 0.32274 0.02851  0.01813  -0.10616 285 LEU A CA  
2463 C C   . LEU A 285 ? 0.39162 0.37510 0.35265 -0.00831 0.00513  -0.11449 285 LEU A C   
2464 O O   . LEU A 285 ? 0.35769 0.42338 0.39071 0.01799  0.02721  -0.09590 285 LEU A O   
2465 C CB  . LEU A 285 ? 0.32813 0.49974 0.33913 -0.08069 0.03329  -0.03162 285 LEU A CB  
2466 C CG  . LEU A 285 ? 0.30347 0.57222 0.36562 -0.13910 -0.04155 0.00300  285 LEU A CG  
2467 C CD1 . LEU A 285 ? 0.42262 0.57990 0.40017 -0.11156 -0.03560 0.03555  285 LEU A CD1 
2468 C CD2 . LEU A 285 ? 0.38924 0.49901 0.36503 0.00059  -0.09065 0.03310  285 LEU A CD2 
2469 N N   . GLU A 286 ? 0.30720 0.41120 0.33321 -0.04762 -0.01964 -0.02300 286 GLU A N   
2470 C CA  . GLU A 286 ? 0.27267 0.43101 0.37619 -0.12292 -0.00350 0.00033  286 GLU A CA  
2471 C C   . GLU A 286 ? 0.42276 0.37332 0.42602 -0.07762 0.01951  -0.00653 286 GLU A C   
2472 O O   . GLU A 286 ? 0.36179 0.41019 0.49055 -0.01668 0.03879  -0.03609 286 GLU A O   
2473 C CB  . GLU A 286 ? 0.24653 0.51920 0.37389 -0.06307 -0.08630 -0.00412 286 GLU A CB  
2474 C CG  . GLU A 286 ? 0.28610 0.59191 0.35885 -0.05927 -0.04106 -0.04829 286 GLU A CG  
2475 C CD  . GLU A 286 ? 0.76383 0.63686 0.39629 -0.04300 -0.00423 -0.05358 286 GLU A CD  
2476 O OE1 . GLU A 286 ? 0.82549 0.59679 0.36947 0.03860  0.00756  -0.03998 286 GLU A OE1 
2477 O OE2 . GLU A 286 ? 0.77092 0.58847 0.41828 -0.11878 0.03342  -0.02491 286 GLU A OE2 
2478 N N   . LYS A 287 ? 0.26323 0.39660 0.35643 -0.03362 -0.03870 -0.01456 287 LYS A N   
2479 C CA  . LYS A 287 ? 0.24244 0.43518 0.34439 -0.02342 -0.06056 -0.03789 287 LYS A CA  
2480 C C   . LYS A 287 ? 0.25767 0.42141 0.36614 -0.02213 -0.04987 -0.01214 287 LYS A C   
2481 O O   . LYS A 287 ? 0.30059 0.42395 0.36512 -0.02096 0.03412  0.03937  287 LYS A O   
2482 C CB  . LYS A 287 ? 0.34136 0.46329 0.33068 -0.01856 0.00604  -0.04785 287 LYS A CB  
2483 C CG  . LYS A 287 ? 0.45639 0.46242 0.36276 -0.03724 -0.04438 -0.09268 287 LYS A CG  
2484 C CD  . LYS A 287 ? 0.58127 0.50878 0.41932 -0.09870 -0.10102 -0.03924 287 LYS A CD  
2485 C CE  . LYS A 287 ? 0.72716 0.50202 0.45319 -0.06034 -0.08764 0.03807  287 LYS A CE  
2486 N NZ  . LYS A 287 ? 0.76637 0.61449 0.49153 -0.03012 -0.05924 0.06787  287 LYS A NZ  
2487 N N   . MET A 288 ? 0.35862 0.40488 0.35940 0.02191  -0.01614 -0.03825 288 MET A N   
2488 C CA  . MET A 288 ? 0.34903 0.40754 0.37655 0.02859  -0.03369 -0.01992 288 MET A CA  
2489 C C   . MET A 288 ? 0.27937 0.44492 0.37979 -0.02613 0.05690  -0.06553 288 MET A C   
2490 O O   . MET A 288 ? 0.31065 0.48151 0.40974 -0.01572 0.01961  -0.06005 288 MET A O   
2491 C CB  . MET A 288 ? 0.53801 0.32428 0.38315 -0.06032 -0.07155 0.00176  288 MET A CB  
2492 C CG  . MET A 288 ? 0.39076 0.27942 0.38935 -0.03542 -0.04126 -0.00781 288 MET A CG  
2493 S SD  . MET A 288 ? 0.66717 0.37656 0.38484 0.03775  -0.00305 -0.00888 288 MET A SD  
2494 C CE  . MET A 288 ? 0.44224 0.47760 0.45056 0.05536  -0.04659 -0.03731 288 MET A CE  
2495 N N   . LEU A 289 ? 0.25986 0.36788 0.33944 0.01667  -0.00778 -0.04905 289 LEU A N   
2496 C CA  . LEU A 289 ? 0.30558 0.30339 0.31867 -0.02897 0.02687  -0.01612 289 LEU A CA  
2497 C C   . LEU A 289 ? 0.35852 0.37782 0.33063 -0.02170 0.04795  0.00369  289 LEU A C   
2498 O O   . LEU A 289 ? 0.44389 0.36461 0.40322 0.08903  0.07035  0.00236  289 LEU A O   
2499 C CB  . LEU A 289 ? 0.27475 0.32516 0.29677 -0.10341 0.05242  -0.00049 289 LEU A CB  
2500 C CG  . LEU A 289 ? 0.31639 0.31672 0.26219 -0.09126 0.04065  0.00409  289 LEU A CG  
2501 C CD1 . LEU A 289 ? 0.40188 0.36591 0.34046 -0.07865 -0.00062 -0.00510 289 LEU A CD1 
2502 C CD2 . LEU A 289 ? 0.41283 0.33482 0.32422 -0.04810 -0.01864 -0.02337 289 LEU A CD2 
2503 N N   . VAL A 290 ? 0.34077 0.39146 0.35479 -0.03573 0.07462  0.02175  290 VAL A N   
2504 C CA  . VAL A 290 ? 0.33282 0.39254 0.36477 -0.05036 0.05438  0.04450  290 VAL A CA  
2505 C C   . VAL A 290 ? 0.34993 0.36799 0.36803 0.02442  0.05597  0.05585  290 VAL A C   
2506 O O   . VAL A 290 ? 0.40574 0.44503 0.35928 -0.01884 0.01561  0.03854  290 VAL A O   
2507 C CB  . VAL A 290 ? 0.54766 0.40248 0.37100 -0.11495 -0.00389 -0.00515 290 VAL A CB  
2508 C CG1 . VAL A 290 ? 0.47283 0.38347 0.38370 -0.10967 0.06183  -0.03420 290 VAL A CG1 
2509 C CG2 . VAL A 290 ? 0.58689 0.46269 0.38350 -0.04025 0.03923  0.00613  290 VAL A CG2 
2510 N N   . LEU A 291 ? 0.29527 0.39627 0.38813 0.02188  0.05635  0.03801  291 LEU A N   
2511 C CA  . LEU A 291 ? 0.42070 0.36730 0.39412 0.15902  0.12453  0.04202  291 LEU A CA  
2512 C C   . LEU A 291 ? 0.34629 0.43666 0.35504 0.07003  0.02188  0.01050  291 LEU A C   
2513 O O   . LEU A 291 ? 0.49047 0.43702 0.34934 0.04250  0.07644  0.03291  291 LEU A O   
2514 C CB  . LEU A 291 ? 0.54932 0.40352 0.41956 0.18512  0.12657  0.03274  291 LEU A CB  
2515 C CG  . LEU A 291 ? 0.64780 0.48421 0.40831 0.14855  0.12624  0.05448  291 LEU A CG  
2516 C CD1 . LEU A 291 ? 0.61169 0.42398 0.33590 0.13237  0.14017  0.06160  291 LEU A CD1 
2517 C CD2 . LEU A 291 ? 0.68465 0.45036 0.43687 0.21225  0.03011  0.03932  291 LEU A CD2 
2518 N N   . ASP A 292 ? 0.36091 0.35570 0.39389 0.01932  0.11562  0.01368  292 ASP A N   
2519 C CA  . ASP A 292 ? 0.41782 0.37555 0.41633 -0.03119 0.09393  0.04284  292 ASP A CA  
2520 C C   . ASP A 292 ? 0.39796 0.33417 0.42702 -0.00691 0.05037  -0.00700 292 ASP A C   
2521 O O   . ASP A 292 ? 0.43406 0.39672 0.41368 0.00399  0.07251  -0.06701 292 ASP A O   
2522 C CB  . ASP A 292 ? 0.45529 0.40699 0.39294 -0.12301 0.05203  0.05363  292 ASP A CB  
2523 C CG  . ASP A 292 ? 0.51985 0.40154 0.43128 -0.09637 0.04230  0.02366  292 ASP A CG  
2524 O OD1 . ASP A 292 ? 0.47321 0.40011 0.44026 -0.05130 0.04292  -0.00968 292 ASP A OD1 
2525 O OD2 . ASP A 292 ? 0.53554 0.42475 0.45910 -0.03436 0.06397  0.02719  292 ASP A OD2 
2526 N N   . SER A 293 ? 0.39791 0.32158 0.39173 0.01685  0.00307  -0.01602 293 SER A N   
2527 C CA  . SER A 293 ? 0.47411 0.38332 0.37691 0.06624  0.03120  -0.06958 293 SER A CA  
2528 C C   . SER A 293 ? 0.45138 0.41860 0.39989 0.05794  0.03889  -0.06864 293 SER A C   
2529 O O   . SER A 293 ? 0.61521 0.41312 0.41923 0.10696  0.02264  -0.01837 293 SER A O   
2530 C CB  . SER A 293 ? 0.48832 0.44465 0.40465 -0.02968 0.02451  -0.05344 293 SER A CB  
2531 O OG  . SER A 293 ? 0.45570 0.48064 0.41039 -0.06183 0.02742  -0.04187 293 SER A OG  
2532 N N   . ASP A 294 ? 0.34435 0.44886 0.34680 -0.03940 0.05647  -0.06710 294 ASP A N   
2533 C CA  . ASP A 294 ? 0.39143 0.49479 0.38944 -0.10446 0.03029  -0.08656 294 ASP A CA  
2534 C C   . ASP A 294 ? 0.46800 0.45088 0.37689 -0.03043 0.02622  -0.06905 294 ASP A C   
2535 O O   . ASP A 294 ? 0.39122 0.43637 0.35815 0.07201  -0.00969 -0.03158 294 ASP A O   
2536 C CB  . ASP A 294 ? 0.43186 0.52385 0.44521 -0.08216 0.05946  -0.09586 294 ASP A CB  
2537 C CG  . ASP A 294 ? 0.49917 0.65778 0.46640 -0.11115 0.07783  -0.04748 294 ASP A CG  
2538 O OD1 . ASP A 294 ? 0.49946 0.70071 0.43955 -0.15365 0.01212  -0.01386 294 ASP A OD1 
2539 O OD2 . ASP A 294 ? 0.58545 0.60620 0.47983 -0.02414 0.04287  -0.05492 294 ASP A OD2 
2540 N N   . LYS A 295 ? 0.45779 0.40553 0.36464 -0.02529 0.04024  -0.00884 295 LYS A N   
2541 C CA  . LYS A 295 ? 0.40820 0.36261 0.34961 0.01006  0.05851  0.00198  295 LYS A CA  
2542 C C   . LYS A 295 ? 0.34329 0.33748 0.30063 0.00101  0.06513  -0.00861 295 LYS A C   
2543 O O   . LYS A 295 ? 0.43602 0.37479 0.31088 0.01922  0.00360  -0.01529 295 LYS A O   
2544 C CB  . LYS A 295 ? 0.37729 0.38258 0.39371 -0.00246 0.04859  0.04297  295 LYS A CB  
2545 C CG  . LYS A 295 ? 0.64503 0.43109 0.46794 -0.05205 0.00610  0.05394  295 LYS A CG  
2546 C CD  . LYS A 295 ? 0.74574 0.43912 0.53050 -0.10006 0.17371  0.08652  295 LYS A CD  
2547 C CE  . LYS A 295 ? 0.81846 0.43687 0.61964 -0.09606 0.08333  0.04933  295 LYS A CE  
2548 N NZ  . LYS A 295 ? 0.94587 0.42556 0.67642 -0.12050 0.05149  0.00729  295 LYS A NZ  
2549 N N   . ARG A 296 ? 0.41500 0.33631 0.27345 0.09003  0.06173  0.04310  296 ARG A N   
2550 C CA  . ARG A 296 ? 0.36209 0.38957 0.33251 0.04742  -0.01887 -0.00126 296 ARG A CA  
2551 C C   . ARG A 296 ? 0.32411 0.32130 0.34482 0.03108  0.02438  0.01365  296 ARG A C   
2552 O O   . ARG A 296 ? 0.26383 0.44860 0.41115 0.03493  0.03710  0.01777  296 ARG A O   
2553 C CB  . ARG A 296 ? 0.37285 0.49108 0.33161 0.03173  -0.04358 -0.05512 296 ARG A CB  
2554 C CG  . ARG A 296 ? 0.47694 0.53849 0.34351 0.01244  -0.02017 -0.09743 296 ARG A CG  
2555 C CD  . ARG A 296 ? 0.37418 0.44826 0.33564 0.04894  -0.04310 -0.08385 296 ARG A CD  
2556 N NE  . ARG A 296 ? 0.40668 0.42997 0.35608 0.03178  0.03576  -0.00740 296 ARG A NE  
2557 C CZ  . ARG A 296 ? 0.25446 0.40327 0.37327 0.07997  0.01374  0.03112  296 ARG A CZ  
2558 N NH1 . ARG A 296 ? 0.32772 0.42198 0.39318 0.03418  0.00362  0.03200  296 ARG A NH1 
2559 N NH2 . ARG A 296 ? 0.28917 0.38506 0.43641 0.01828  0.04867  0.03818  296 ARG A NH2 
2560 N N   . ILE A 297 ? 0.34966 0.28103 0.36314 -0.02325 -0.04188 0.02885  297 ILE A N   
2561 C CA  . ILE A 297 ? 0.32227 0.27794 0.39457 0.01513  -0.03038 0.02838  297 ILE A CA  
2562 C C   . ILE A 297 ? 0.29061 0.37103 0.35398 0.07877  0.00327  0.00383  297 ILE A C   
2563 O O   . ILE A 297 ? 0.29375 0.39126 0.35350 -0.00142 0.02643  -0.00759 297 ILE A O   
2564 C CB  . ILE A 297 ? 0.37657 0.28037 0.35890 -0.00654 0.02893  0.00357  297 ILE A CB  
2565 C CG1 . ILE A 297 ? 0.33617 0.31269 0.33569 -0.03841 0.04479  -0.01642 297 ILE A CG1 
2566 C CG2 . ILE A 297 ? 0.35350 0.34738 0.38465 -0.05886 0.03535  0.06135  297 ILE A CG2 
2567 C CD1 . ILE A 297 ? 0.31208 0.37100 0.38536 -0.00821 0.00055  0.00490  297 ILE A CD1 
2568 N N   . THR A 298 ? 0.26336 0.35978 0.35877 0.06646  -0.04681 0.01265  298 THR A N   
2569 C CA  . THR A 298 ? 0.27098 0.31954 0.36078 -0.00274 -0.01997 0.02759  298 THR A CA  
2570 C C   . THR A 298 ? 0.33287 0.34157 0.37023 0.02385  0.02679  0.01586  298 THR A C   
2571 O O   . THR A 298 ? 0.32527 0.43860 0.37168 0.02639  -0.02539 0.01787  298 THR A O   
2572 C CB  . THR A 298 ? 0.34314 0.33716 0.37786 0.02189  0.04126  0.00058  298 THR A CB  
2573 O OG1 . THR A 298 ? 0.32102 0.40788 0.39484 0.01862  0.04703  0.02102  298 THR A OG1 
2574 C CG2 . THR A 298 ? 0.53849 0.28306 0.38857 0.08075  0.08025  -0.00857 298 THR A CG2 
2575 N N   . ALA A 299 ? 0.35828 0.29586 0.33935 0.03757  0.01933  0.04336  299 ALA A N   
2576 C CA  . ALA A 299 ? 0.31167 0.34071 0.30248 0.03375  -0.04172 0.01103  299 ALA A CA  
2577 C C   . ALA A 299 ? 0.31015 0.37360 0.33450 0.02066  0.02652  0.02942  299 ALA A C   
2578 O O   . ALA A 299 ? 0.36047 0.29363 0.33271 0.01382  0.00609  0.01016  299 ALA A O   
2579 C CB  . ALA A 299 ? 0.38274 0.38150 0.30282 0.01198  -0.02368 -0.00361 299 ALA A CB  
2580 N N   . ALA A 300 ? 0.27162 0.41931 0.30419 0.05913  0.03640  0.01880  300 ALA A N   
2581 C CA  . ALA A 300 ? 0.31109 0.37809 0.33834 0.06717  0.07512  -0.01335 300 ALA A CA  
2582 C C   . ALA A 300 ? 0.38136 0.38479 0.35986 0.04001  0.01589  0.02787  300 ALA A C   
2583 O O   . ALA A 300 ? 0.47499 0.40099 0.35648 0.03030  0.03913  -0.00989 300 ALA A O   
2584 C CB  . ALA A 300 ? 0.35690 0.38154 0.39208 0.11244  0.06609  -0.02548 300 ALA A CB  
2585 N N   . GLN A 301 ? 0.32346 0.35999 0.37682 0.03896  -0.00047 0.02945  301 GLN A N   
2586 C CA  . GLN A 301 ? 0.26039 0.37319 0.36499 0.00982  -0.06601 0.05901  301 GLN A CA  
2587 C C   . GLN A 301 ? 0.31751 0.38260 0.34452 -0.02157 -0.05598 0.00985  301 GLN A C   
2588 O O   . GLN A 301 ? 0.46127 0.38874 0.34090 -0.01514 -0.06506 -0.00795 301 GLN A O   
2589 C CB  . GLN A 301 ? 0.32435 0.33793 0.35161 0.00159  0.00105  0.09210  301 GLN A CB  
2590 C CG  . GLN A 301 ? 0.40956 0.38958 0.37507 -0.02650 0.05542  0.02744  301 GLN A CG  
2591 C CD  . GLN A 301 ? 0.43320 0.45475 0.38818 -0.01960 0.07109  0.03473  301 GLN A CD  
2592 O OE1 . GLN A 301 ? 0.32970 0.44097 0.34768 0.04058  0.05293  -0.04552 301 GLN A OE1 
2593 N NE2 . GLN A 301 ? 0.43956 0.49110 0.35596 0.10873  -0.00114 0.05732  301 GLN A NE2 
2594 N N   . ALA A 302 ? 0.39333 0.36447 0.28590 0.00960  0.01162  -0.03663 302 ALA A N   
2595 C CA  . ALA A 302 ? 0.33877 0.35942 0.33362 0.01411  0.03049  -0.03789 302 ALA A CA  
2596 C C   . ALA A 302 ? 0.39708 0.41237 0.36419 0.03270  -0.00998 -0.03090 302 ALA A C   
2597 O O   . ALA A 302 ? 0.34295 0.39602 0.37449 0.00163  -0.00695 -0.02494 302 ALA A O   
2598 C CB  . ALA A 302 ? 0.34246 0.37034 0.38010 0.03974  0.01191  0.00690  302 ALA A CB  
2599 N N   . LEU A 303 ? 0.43507 0.38953 0.36916 0.10641  0.04861  0.00602  303 LEU A N   
2600 C CA  . LEU A 303 ? 0.35907 0.38174 0.35805 0.03158  -0.08618 -0.01649 303 LEU A CA  
2601 C C   . LEU A 303 ? 0.29824 0.36610 0.41676 -0.06354 -0.04752 -0.01440 303 LEU A C   
2602 O O   . LEU A 303 ? 0.36299 0.38959 0.46275 -0.01716 -0.00256 -0.03275 303 LEU A O   
2603 C CB  . LEU A 303 ? 0.41596 0.38598 0.34841 0.01802  -0.13167 0.01356  303 LEU A CB  
2604 C CG  . LEU A 303 ? 0.32220 0.42993 0.38957 -0.05466 -0.09048 -0.02782 303 LEU A CG  
2605 C CD1 . LEU A 303 ? 0.36645 0.50767 0.40684 -0.01948 -0.04979 -0.06604 303 LEU A CD1 
2606 C CD2 . LEU A 303 ? 0.31768 0.42161 0.39247 -0.01404 -0.00449 -0.03258 303 LEU A CD2 
2607 N N   . ALA A 304 ? 0.37319 0.41885 0.37471 -0.05451 -0.03760 0.00395  304 ALA A N   
2608 C CA  . ALA A 304 ? 0.41609 0.40071 0.39614 -0.02651 0.00386  0.01605  304 ALA A CA  
2609 C C   . ALA A 304 ? 0.38852 0.41858 0.40239 -0.02652 -0.06081 -0.04424 304 ALA A C   
2610 O O   . ALA A 304 ? 0.34394 0.47459 0.38860 0.02443  -0.06096 -0.09274 304 ALA A O   
2611 C CB  . ALA A 304 ? 0.38159 0.37651 0.39308 -0.02068 0.05799  0.03726  304 ALA A CB  
2612 N N   . HIS A 305 ? 0.29514 0.42296 0.41512 0.00450  -0.02756 -0.05200 305 HIS A N   
2613 C CA  . HIS A 305 ? 0.31888 0.41141 0.43057 0.01936  -0.01204 -0.06613 305 HIS A CA  
2614 C C   . HIS A 305 ? 0.33876 0.45326 0.44573 -0.03007 -0.02025 -0.08392 305 HIS A C   
2615 O O   . HIS A 305 ? 0.35048 0.45668 0.39667 -0.03891 0.00722  -0.08169 305 HIS A O   
2616 C CB  . HIS A 305 ? 0.27778 0.44860 0.40382 0.04215  0.01636  -0.07054 305 HIS A CB  
2617 C CG  . HIS A 305 ? 0.37524 0.41203 0.38966 0.03974  -0.01802 -0.03206 305 HIS A CG  
2618 N ND1 . HIS A 305 ? 0.41959 0.40269 0.38433 -0.11809 0.01847  0.01264  305 HIS A ND1 
2619 C CD2 . HIS A 305 ? 0.48290 0.44278 0.38849 0.05569  -0.04190 -0.05878 305 HIS A CD2 
2620 C CE1 . HIS A 305 ? 0.44330 0.39133 0.41280 -0.03938 -0.05385 -0.00963 305 HIS A CE1 
2621 N NE2 . HIS A 305 ? 0.45688 0.37806 0.38920 0.04796  -0.01949 -0.04744 305 HIS A NE2 
2622 N N   . ALA A 306 ? 0.32804 0.47975 0.43218 -0.07231 -0.08364 -0.07945 306 ALA A N   
2623 C CA  . ALA A 306 ? 0.34496 0.44361 0.44232 -0.03408 -0.08572 -0.09168 306 ALA A CA  
2624 C C   . ALA A 306 ? 0.39082 0.42941 0.47836 -0.03013 -0.05518 -0.10807 306 ALA A C   
2625 O O   . ALA A 306 ? 0.41423 0.39127 0.54143 -0.03840 -0.00923 -0.08134 306 ALA A O   
2626 C CB  . ALA A 306 ? 0.43747 0.47057 0.44559 -0.06644 -0.04874 -0.12211 306 ALA A CB  
2627 N N   . TYR A 307 ? 0.34443 0.41998 0.45356 0.00943  -0.08063 -0.08047 307 TYR A N   
2628 C CA  . TYR A 307 ? 0.40555 0.38776 0.42149 -0.01639 -0.03691 -0.07489 307 TYR A CA  
2629 C C   . TYR A 307 ? 0.38147 0.39781 0.46771 -0.00764 -0.02990 -0.06302 307 TYR A C   
2630 O O   . TYR A 307 ? 0.46542 0.37196 0.50234 -0.05301 0.01829  -0.03909 307 TYR A O   
2631 C CB  . TYR A 307 ? 0.37533 0.34812 0.39028 -0.00488 -0.02070 -0.07955 307 TYR A CB  
2632 C CG  . TYR A 307 ? 0.44322 0.38182 0.39861 -0.03010 -0.01488 -0.03863 307 TYR A CG  
2633 C CD1 . TYR A 307 ? 0.41599 0.40288 0.39806 -0.03296 0.00150  -0.03468 307 TYR A CD1 
2634 C CD2 . TYR A 307 ? 0.41824 0.41082 0.42949 -0.03537 0.00844  -0.02427 307 TYR A CD2 
2635 C CE1 . TYR A 307 ? 0.46945 0.41459 0.40963 0.00012  0.03332  -0.02302 307 TYR A CE1 
2636 C CE2 . TYR A 307 ? 0.42933 0.39857 0.43675 -0.02418 0.03115  0.01529  307 TYR A CE2 
2637 C CZ  . TYR A 307 ? 0.48455 0.39835 0.42078 0.03687  0.05045  0.00586  307 TYR A CZ  
2638 O OH  . TYR A 307 ? 0.54544 0.44538 0.39909 -0.05378 0.01963  -0.07356 307 TYR A OH  
2639 N N   . PHE A 308 ? 0.38619 0.41397 0.47671 0.00398  -0.05638 -0.09006 308 PHE A N   
2640 C CA  . PHE A 308 ? 0.38502 0.38028 0.47299 -0.03976 -0.07887 -0.08641 308 PHE A CA  
2641 C C   . PHE A 308 ? 0.44948 0.38780 0.50739 -0.05257 -0.04070 -0.11030 308 PHE A C   
2642 O O   . PHE A 308 ? 0.45117 0.42145 0.52237 -0.00012 -0.05466 -0.12728 308 PHE A O   
2643 C CB  . PHE A 308 ? 0.38401 0.40148 0.42554 0.00018  -0.07651 -0.05287 308 PHE A CB  
2644 C CG  . PHE A 308 ? 0.34169 0.39088 0.41875 -0.00214 -0.02926 -0.05492 308 PHE A CG  
2645 C CD1 . PHE A 308 ? 0.30622 0.41274 0.41053 0.00384  0.01557  -0.06406 308 PHE A CD1 
2646 C CD2 . PHE A 308 ? 0.31028 0.41544 0.39041 -0.06045 -0.04227 0.00169  308 PHE A CD2 
2647 C CE1 . PHE A 308 ? 0.35628 0.42483 0.41136 -0.02247 -0.01276 -0.05903 308 PHE A CE1 
2648 C CE2 . PHE A 308 ? 0.35561 0.46175 0.32608 -0.01894 -0.02978 -0.03948 308 PHE A CE2 
2649 C CZ  . PHE A 308 ? 0.37345 0.47533 0.36777 -0.02008 0.02027  -0.04380 308 PHE A CZ  
2650 N N   . ALA A 309 ? 0.55434 0.36241 0.52167 -0.05144 -0.00892 -0.14872 309 ALA A N   
2651 C CA  . ALA A 309 ? 0.68108 0.33905 0.51281 -0.06250 -0.09400 -0.14497 309 ALA A CA  
2652 C C   . ALA A 309 ? 0.84988 0.37566 0.51373 -0.03938 -0.09213 -0.10996 309 ALA A C   
2653 O O   . ALA A 309 ? 1.09034 0.32873 0.52506 0.02310  -0.03192 -0.11800 309 ALA A O   
2654 C CB  . ALA A 309 ? 0.65930 0.35635 0.50202 0.05066  -0.13750 -0.11305 309 ALA A CB  
2655 N N   . GLN A 310 ? 0.61341 0.38512 0.51438 -0.11822 -0.08189 -0.08841 310 GLN A N   
2656 C CA  . GLN A 310 ? 0.62698 0.42777 0.59007 -0.07409 -0.05668 -0.04081 310 GLN A CA  
2657 C C   . GLN A 310 ? 0.52843 0.42021 0.59427 -0.01161 -0.04911 -0.02295 310 GLN A C   
2658 O O   . GLN A 310 ? 0.56351 0.36254 0.64659 -0.03670 -0.04299 -0.02838 310 GLN A O   
2659 C CB  . GLN A 310 ? 0.72149 0.49088 0.65010 -0.07165 0.01058  -0.00472 310 GLN A CB  
2660 C CG  . GLN A 310 ? 0.79941 0.69451 0.72352 -0.07904 -0.00519 0.02955  310 GLN A CG  
2661 C CD  . GLN A 310 ? 0.96516 0.89260 0.81340 -0.08195 -0.02770 0.02343  310 GLN A CD  
2662 O OE1 . GLN A 310 ? 0.87124 0.98513 0.84687 -0.05758 -0.03973 0.03122  310 GLN A OE1 
2663 N NE2 . GLN A 310 ? 1.08701 0.90364 0.84425 -0.07742 -0.03052 0.00054  310 GLN A NE2 
2664 N N   . TYR A 311 ? 0.48412 0.43342 0.54740 -0.03231 0.01102  -0.05688 311 TYR A N   
2665 C CA  . TYR A 311 ? 0.46715 0.42906 0.51020 -0.00584 -0.00009 -0.03925 311 TYR A CA  
2666 C C   . TYR A 311 ? 0.42414 0.38599 0.52147 -0.04559 -0.00451 -0.05355 311 TYR A C   
2667 O O   . TYR A 311 ? 0.49381 0.34468 0.55152 -0.04055 0.00500  -0.04158 311 TYR A O   
2668 C CB  . TYR A 311 ? 0.49124 0.41401 0.49234 -0.07577 -0.01854 -0.01056 311 TYR A CB  
2669 C CG  . TYR A 311 ? 0.43239 0.43066 0.53013 -0.12181 0.01986  -0.03000 311 TYR A CG  
2670 C CD1 . TYR A 311 ? 0.47836 0.49341 0.53288 0.04993  0.03403  0.04012  311 TYR A CD1 
2671 C CD2 . TYR A 311 ? 0.52818 0.39306 0.53287 -0.07677 0.08509  -0.07307 311 TYR A CD2 
2672 C CE1 . TYR A 311 ? 0.45537 0.52135 0.54989 0.04458  0.05831  0.01185  311 TYR A CE1 
2673 C CE2 . TYR A 311 ? 0.65220 0.46193 0.51450 -0.07535 0.10146  -0.05534 311 TYR A CE2 
2674 C CZ  . TYR A 311 ? 0.62806 0.52201 0.52076 -0.07413 0.05576  -0.04131 311 TYR A CZ  
2675 O OH  . TYR A 311 ? 0.74302 0.55426 0.52033 -0.14928 0.07819  -0.06880 311 TYR A OH  
2676 N N   . HIS A 312 ? 0.39961 0.36710 0.49912 -0.00425 0.06141  -0.06163 312 HIS A N   
2677 C CA  . HIS A 312 ? 0.37389 0.38850 0.49525 -0.02447 0.00691  -0.03310 312 HIS A CA  
2678 C C   . HIS A 312 ? 0.42950 0.37767 0.54625 -0.06969 -0.04171 -0.04699 312 HIS A C   
2679 O O   . HIS A 312 ? 0.50297 0.33617 0.58879 -0.00448 -0.07324 -0.10501 312 HIS A O   
2680 C CB  . HIS A 312 ? 0.39757 0.41716 0.49203 0.03221  -0.02033 0.03831  312 HIS A CB  
2681 C CG  . HIS A 312 ? 0.40889 0.42992 0.46842 -0.02635 -0.02720 0.00308  312 HIS A CG  
2682 N ND1 . HIS A 312 ? 0.42425 0.41637 0.45683 -0.04679 0.02878  0.01329  312 HIS A ND1 
2683 C CD2 . HIS A 312 ? 0.48395 0.45050 0.46070 -0.04604 0.01457  -0.00647 312 HIS A CD2 
2684 C CE1 . HIS A 312 ? 0.42855 0.47005 0.44722 0.01472  -0.00791 -0.01804 312 HIS A CE1 
2685 N NE2 . HIS A 312 ? 0.51792 0.46622 0.44291 -0.01749 0.02832  -0.00679 312 HIS A NE2 
2686 N N   . ASP A 313 ? 0.34722 0.37259 0.53893 -0.01785 -0.03508 -0.04576 313 ASP A N   
2687 C CA  . ASP A 313 ? 0.39902 0.38196 0.53593 0.08852  0.00588  0.00277  313 ASP A CA  
2688 C C   . ASP A 313 ? 0.46867 0.36747 0.48817 0.07740  0.03810  0.01313  313 ASP A C   
2689 O O   . ASP A 313 ? 0.47555 0.39378 0.47469 0.04867  0.02964  0.04031  313 ASP A O   
2690 C CB  . ASP A 313 ? 0.46571 0.39356 0.57118 0.17028  -0.01109 -0.00767 313 ASP A CB  
2691 C CG  . ASP A 313 ? 0.60202 0.44870 0.60831 0.09401  -0.02572 -0.00213 313 ASP A CG  
2692 O OD1 . ASP A 313 ? 0.61290 0.49958 0.59114 0.07532  -0.00153 -0.06948 313 ASP A OD1 
2693 O OD2 . ASP A 313 ? 0.71859 0.43403 0.66967 0.09632  -0.03606 0.01843  313 ASP A OD2 
2694 N N   . PRO A 314 ? 0.48183 0.46485 0.48213 0.10199  0.02967  0.02938  314 PRO A N   
2695 C CA  . PRO A 314 ? 0.44018 0.48036 0.46058 0.00593  0.06398  0.11146  314 PRO A CA  
2696 C C   . PRO A 314 ? 0.47064 0.48638 0.50404 0.00743  0.04718  0.04450  314 PRO A C   
2697 O O   . PRO A 314 ? 0.42021 0.52373 0.56025 -0.00376 -0.02445 0.04320  314 PRO A O   
2698 C CB  . PRO A 314 ? 0.53050 0.59929 0.44158 -0.04366 0.01783  0.13119  314 PRO A CB  
2699 C CG  . PRO A 314 ? 0.63881 0.59721 0.46283 -0.04581 -0.02610 0.09053  314 PRO A CG  
2700 C CD  . PRO A 314 ? 0.63756 0.55463 0.46217 0.04106  -0.04023 0.04447  314 PRO A CD  
2701 N N   . ASP A 315 ? 0.48806 0.46895 0.49512 0.05266  0.07789  -0.01107 315 ASP A N   
2702 C CA  . ASP A 315 ? 0.54889 0.51070 0.47451 0.12422  0.08926  -0.05218 315 ASP A CA  
2703 C C   . ASP A 315 ? 0.53122 0.48573 0.42955 0.09987  0.04235  -0.03677 315 ASP A C   
2704 O O   . ASP A 315 ? 0.47410 0.53690 0.43663 0.10738  -0.00021 -0.03047 315 ASP A O   
2705 C CB  . ASP A 315 ? 0.61356 0.54209 0.51549 0.11576  0.14678  -0.09172 315 ASP A CB  
2706 C CG  . ASP A 315 ? 0.77696 0.62340 0.55731 0.13098  0.13498  -0.07562 315 ASP A CG  
2707 O OD1 . ASP A 315 ? 0.63887 0.64183 0.58880 0.13071  0.13467  -0.06939 315 ASP A OD1 
2708 O OD2 . ASP A 315 ? 0.94164 0.68300 0.57220 0.08067  0.11951  -0.06549 315 ASP A OD2 
2709 N N   . ASP A 316 ? 0.42043 0.46773 0.45078 0.06352  -0.02808 -0.03166 316 ASP A N   
2710 C CA  . ASP A 316 ? 0.57248 0.43957 0.40072 0.07910  -0.03018 -0.02399 316 ASP A CA  
2711 C C   . ASP A 316 ? 0.47982 0.40301 0.39876 0.04020  -0.08988 -0.06231 316 ASP A C   
2712 O O   . ASP A 316 ? 0.53385 0.45004 0.39633 0.04137  0.00603  -0.02138 316 ASP A O   
2713 C CB  . ASP A 316 ? 0.78498 0.44240 0.46923 0.05682  0.04870  -0.02951 316 ASP A CB  
2714 C CG  . ASP A 316 ? 0.96999 0.55406 0.57500 0.09607  0.13275  0.02089  316 ASP A CG  
2715 O OD1 . ASP A 316 ? 0.95533 0.60084 0.59871 0.24102  0.15797  0.05683  316 ASP A OD1 
2716 O OD2 . ASP A 316 ? 1.04662 0.57624 0.66454 0.04418  0.15736  0.01946  316 ASP A OD2 
2717 N N   . GLU A 317 ? 0.49321 0.38427 0.41385 0.07957  0.01909  -0.01624 317 GLU A N   
2718 C CA  . GLU A 317 ? 0.38510 0.43902 0.40881 0.02858  -0.06283 -0.06115 317 GLU A CA  
2719 C C   . GLU A 317 ? 0.46925 0.44717 0.41267 0.02663  0.00440  -0.04909 317 GLU A C   
2720 O O   . GLU A 317 ? 0.38999 0.41495 0.41643 0.05146  -0.01748 -0.00573 317 GLU A O   
2721 C CB  . GLU A 317 ? 0.37983 0.42944 0.44713 0.05331  -0.11762 -0.05417 317 GLU A CB  
2722 C CG  . GLU A 317 ? 0.39735 0.44487 0.44745 -0.04378 -0.06432 -0.05400 317 GLU A CG  
2723 C CD  . GLU A 317 ? 0.46554 0.47539 0.44623 0.08659  -0.04183 -0.04051 317 GLU A CD  
2724 O OE1 . GLU A 317 ? 0.55247 0.49743 0.39026 0.06039  -0.10101 -0.02706 317 GLU A OE1 
2725 O OE2 . GLU A 317 ? 0.43775 0.47150 0.46154 0.01860  0.03508  -0.08875 317 GLU A OE2 
2726 N N   . PRO A 318 ? 0.38562 0.43020 0.41202 0.03425  -0.01833 -0.02086 318 PRO A N   
2727 C CA  . PRO A 318 ? 0.48291 0.41133 0.42196 0.03797  -0.03289 0.00565  318 PRO A CA  
2728 C C   . PRO A 318 ? 0.38839 0.40001 0.44629 0.02562  0.00965  -0.04025 318 PRO A C   
2729 O O   . PRO A 318 ? 0.37257 0.39085 0.46455 0.04019  0.01878  0.02102  318 PRO A O   
2730 C CB  . PRO A 318 ? 0.53954 0.44809 0.45603 0.00716  -0.00248 0.01495  318 PRO A CB  
2731 C CG  . PRO A 318 ? 0.40126 0.44694 0.44439 0.07775  0.02159  0.01976  318 PRO A CG  
2732 C CD  . PRO A 318 ? 0.34615 0.43297 0.42742 0.04094  -0.03524 0.00465  318 PRO A CD  
2733 N N   . VAL A 319 ? 0.35402 0.37582 0.49197 -0.00328 0.02643  -0.03705 319 VAL A N   
2734 C CA  . VAL A 319 ? 0.31487 0.39657 0.48861 0.02879  0.01624  -0.01626 319 VAL A CA  
2735 C C   . VAL A 319 ? 0.22239 0.38541 0.44907 0.01269  -0.00570 0.01464  319 VAL A C   
2736 O O   . VAL A 319 ? 0.35095 0.42474 0.45959 0.04825  -0.00626 0.00299  319 VAL A O   
2737 C CB  . VAL A 319 ? 0.32161 0.50146 0.50439 0.09978  -0.05991 0.00703  319 VAL A CB  
2738 C CG1 . VAL A 319 ? 0.40514 0.57283 0.51575 0.07450  -0.03065 -0.00396 319 VAL A CG1 
2739 C CG2 . VAL A 319 ? 0.38046 0.55666 0.51545 0.10112  -0.01565 0.04187  319 VAL A CG2 
2740 N N   . ALA A 320 ? 0.37231 0.36912 0.47330 -0.00342 -0.03001 0.01391  320 ALA A N   
2741 C CA  . ALA A 320 ? 0.26909 0.43526 0.45078 0.03320  0.04447  0.00205  320 ALA A CA  
2742 C C   . ALA A 320 ? 0.25728 0.36974 0.42837 0.03620  0.01485  0.01356  320 ALA A C   
2743 O O   . ALA A 320 ? 0.34820 0.41014 0.42375 0.04326  0.05139  0.01788  320 ALA A O   
2744 C CB  . ALA A 320 ? 0.28725 0.42170 0.43546 0.00573  0.07343  -0.00941 320 ALA A CB  
2745 N N   . ASP A 321 ? 0.28325 0.38009 0.39331 0.03294  -0.00010 0.00466  321 ASP A N   
2746 C CA  . ASP A 321 ? 0.28655 0.34904 0.41713 0.05489  0.05906  0.02276  321 ASP A CA  
2747 C C   . ASP A 321 ? 0.34933 0.42353 0.41649 0.01518  0.07311  0.03867  321 ASP A C   
2748 O O   . ASP A 321 ? 0.36436 0.44755 0.38802 -0.02805 0.00521  0.01966  321 ASP A O   
2749 C CB  . ASP A 321 ? 0.33793 0.36885 0.44817 0.14007  0.00515  0.00855  321 ASP A CB  
2750 C CG  . ASP A 321 ? 0.56617 0.42368 0.47021 0.16416  0.03216  -0.02188 321 ASP A CG  
2751 O OD1 . ASP A 321 ? 0.57789 0.42729 0.50567 0.07342  -0.04425 -0.05770 321 ASP A OD1 
2752 O OD2 . ASP A 321 ? 0.73903 0.49730 0.51353 0.05877  0.08464  -0.03212 321 ASP A OD2 
2753 N N   . PRO A 322 ? 0.29409 0.47095 0.43188 -0.02821 0.09362  0.00401  322 PRO A N   
2754 C CA  . PRO A 322 ? 0.37181 0.44063 0.41511 -0.01827 0.06452  0.01897  322 PRO A CA  
2755 C C   . PRO A 322 ? 0.35812 0.43241 0.43164 -0.02356 0.05932  0.00410  322 PRO A C   
2756 O O   . PRO A 322 ? 0.40882 0.40520 0.48446 -0.06426 0.02026  0.03199  322 PRO A O   
2757 C CB  . PRO A 322 ? 0.34479 0.50628 0.41443 0.01652  0.10746  0.00847  322 PRO A CB  
2758 C CG  . PRO A 322 ? 0.43681 0.47874 0.45170 0.00839  0.11103  0.02446  322 PRO A CG  
2759 C CD  . PRO A 322 ? 0.33357 0.49066 0.44111 -0.00618 0.12813  0.00650  322 PRO A CD  
2760 N N   . TYR A 323 ? 0.32256 0.47828 0.42397 -0.00861 0.01312  -0.03395 323 TYR A N   
2761 C CA  . TYR A 323 ? 0.27277 0.44305 0.41146 0.02962  0.04888  -0.02408 323 TYR A CA  
2762 C C   . TYR A 323 ? 0.35313 0.44219 0.45205 -0.04965 -0.03817 0.00147  323 TYR A C   
2763 O O   . TYR A 323 ? 0.41760 0.41969 0.44823 -0.07509 -0.04643 0.06073  323 TYR A O   
2764 C CB  . TYR A 323 ? 0.28912 0.45780 0.38047 0.04944  0.03543  0.00208  323 TYR A CB  
2765 C CG  . TYR A 323 ? 0.33228 0.49854 0.39661 -0.04531 0.03459  0.04288  323 TYR A CG  
2766 C CD1 . TYR A 323 ? 0.47944 0.53695 0.45017 -0.05730 -0.02621 0.03927  323 TYR A CD1 
2767 C CD2 . TYR A 323 ? 0.28550 0.56567 0.41490 -0.01414 0.07441  0.00642  323 TYR A CD2 
2768 C CE1 . TYR A 323 ? 0.46156 0.62645 0.49418 -0.08276 -0.01654 0.01691  323 TYR A CE1 
2769 C CE2 . TYR A 323 ? 0.38033 0.65805 0.45051 -0.04687 0.03912  0.03124  323 TYR A CE2 
2770 C CZ  . TYR A 323 ? 0.41964 0.71868 0.51046 -0.11239 0.02480  0.01432  323 TYR A CZ  
2771 O OH  . TYR A 323 ? 0.48461 0.81219 0.56622 -0.18241 0.04064  0.01100  323 TYR A OH  
2772 N N   . ASP A 324 ? 0.35187 0.35889 0.46708 -0.11735 -0.02186 -0.01363 324 ASP A N   
2773 C CA  . ASP A 324 ? 0.31344 0.39273 0.47528 -0.05880 -0.00612 0.00326  324 ASP A CA  
2774 C C   . ASP A 324 ? 0.30515 0.44777 0.46291 -0.03813 0.00711  0.01394  324 ASP A C   
2775 O O   . ASP A 324 ? 0.36114 0.48806 0.42905 -0.07437 0.07066  -0.01063 324 ASP A O   
2776 C CB  . ASP A 324 ? 0.30794 0.41372 0.50923 -0.13505 -0.00928 -0.04396 324 ASP A CB  
2777 C CG  . ASP A 324 ? 0.32205 0.41628 0.56769 0.01454  -0.03591 -0.03138 324 ASP A CG  
2778 O OD1 . ASP A 324 ? 0.38938 0.42449 0.56889 -0.05576 0.08483  0.00319  324 ASP A OD1 
2779 O OD2 . ASP A 324 ? 0.38583 0.43363 0.61617 -0.03986 -0.04013 -0.03684 324 ASP A OD2 
2780 N N   . GLN A 325 ? 0.35597 0.41894 0.47300 -0.04627 -0.00309 0.03998  325 GLN A N   
2781 C CA  . GLN A 325 ? 0.24224 0.46151 0.51752 -0.07025 0.04457  0.00865  325 GLN A CA  
2782 C C   . GLN A 325 ? 0.41391 0.45740 0.50820 -0.06384 -0.02412 0.06202  325 GLN A C   
2783 O O   . GLN A 325 ? 0.34432 0.49462 0.55532 -0.07397 -0.05295 0.08387  325 GLN A O   
2784 C CB  . GLN A 325 ? 0.34336 0.50553 0.61286 -0.02286 0.11043  -0.05456 325 GLN A CB  
2785 C CG  . GLN A 325 ? 0.42790 0.61232 0.65761 0.06603  0.05118  -0.07543 325 GLN A CG  
2786 C CD  . GLN A 325 ? 0.49783 0.64054 0.67984 0.04495  -0.02616 -0.07096 325 GLN A CD  
2787 O OE1 . GLN A 325 ? 0.42414 0.61894 0.71454 0.03034  0.01270  -0.12866 325 GLN A OE1 
2788 N NE2 . GLN A 325 ? 0.44627 0.58951 0.65518 -0.02235 -0.09062 -0.05661 325 GLN A NE2 
2789 N N   . SER A 326 ? 0.33943 0.43492 0.46192 -0.11250 -0.02097 0.08400  326 SER A N   
2790 C CA  . SER A 326 ? 0.37538 0.43652 0.48285 -0.04816 -0.00967 0.03000  326 SER A CA  
2791 C C   . SER A 326 ? 0.34897 0.40996 0.46561 -0.01308 0.01578  0.02142  326 SER A C   
2792 O O   . SER A 326 ? 0.38376 0.38907 0.48231 -0.04663 0.02209  0.01726  326 SER A O   
2793 C CB  . SER A 326 ? 0.36037 0.51216 0.48357 0.03307  -0.03388 -0.01483 326 SER A CB  
2794 O OG  . SER A 326 ? 0.34008 0.58330 0.48639 0.01240  -0.03528 -0.03302 326 SER A OG  
2795 N N   . PHE A 327 ? 0.34983 0.41162 0.47727 -0.00638 0.05365  0.02787  327 PHE A N   
2796 C CA  . PHE A 327 ? 0.36025 0.35408 0.44559 0.00482  0.03709  0.04472  327 PHE A CA  
2797 C C   . PHE A 327 ? 0.31967 0.37288 0.43632 -0.03789 -0.01064 0.06025  327 PHE A C   
2798 O O   . PHE A 327 ? 0.57814 0.37321 0.40518 0.02357  0.05671  0.02898  327 PHE A O   
2799 C CB  . PHE A 327 ? 0.32648 0.38547 0.44600 -0.04740 -0.00395 0.06127  327 PHE A CB  
2800 C CG  . PHE A 327 ? 0.40522 0.36011 0.46168 -0.02407 0.01608  0.07513  327 PHE A CG  
2801 C CD1 . PHE A 327 ? 0.38030 0.41616 0.45785 -0.03087 0.02521  0.07183  327 PHE A CD1 
2802 C CD2 . PHE A 327 ? 0.44064 0.34780 0.49968 -0.03459 0.02089  0.07474  327 PHE A CD2 
2803 C CE1 . PHE A 327 ? 0.43628 0.39249 0.45009 -0.00852 0.03566  0.09073  327 PHE A CE1 
2804 C CE2 . PHE A 327 ? 0.41870 0.33519 0.48538 0.02786  0.07698  0.07801  327 PHE A CE2 
2805 C CZ  . PHE A 327 ? 0.40930 0.37373 0.46382 -0.00002 0.04433  0.13048  327 PHE A CZ  
2806 N N   . GLU A 328 ? 0.28135 0.39687 0.47625 0.03939  0.04689  0.09664  328 GLU A N   
2807 C CA  . GLU A 328 ? 0.36714 0.41326 0.50928 0.06011  0.02387  0.07701  328 GLU A CA  
2808 C C   . GLU A 328 ? 0.45438 0.40188 0.52727 0.03531  0.05261  0.10594  328 GLU A C   
2809 O O   . GLU A 328 ? 0.52101 0.42551 0.49207 0.06220  0.04508  0.08741  328 GLU A O   
2810 C CB  . GLU A 328 ? 0.37153 0.41621 0.52080 -0.02404 0.07142  0.04248  328 GLU A CB  
2811 C CG  . GLU A 328 ? 0.47001 0.39546 0.50999 -0.05970 0.07265  0.05976  328 GLU A CG  
2812 C CD  . GLU A 328 ? 0.51652 0.46293 0.54855 -0.02168 0.04570  0.07517  328 GLU A CD  
2813 O OE1 . GLU A 328 ? 0.53409 0.47544 0.54739 0.06196  0.03292  0.10937  328 GLU A OE1 
2814 O OE2 . GLU A 328 ? 0.39756 0.50688 0.57949 -0.02628 0.04822  0.07466  328 GLU A OE2 
2815 N N   . SER A 329 ? 0.43634 0.45307 0.56692 0.05293  0.06885  0.11957  329 SER A N   
2816 C CA  . SER A 329 ? 0.57794 0.48459 0.60585 -0.04235 0.11395  0.17260  329 SER A CA  
2817 C C   . SER A 329 ? 0.61732 0.42183 0.64182 -0.01439 0.11602  0.13484  329 SER A C   
2818 O O   . SER A 329 ? 0.72055 0.42326 0.67332 -0.00065 0.10628  0.18734  329 SER A O   
2819 C CB  . SER A 329 ? 0.81460 0.56289 0.62442 -0.15700 0.08901  0.24121  329 SER A CB  
2820 O OG  . SER A 329 ? 1.11894 0.68608 0.64852 -0.08864 0.05869  0.27323  329 SER A OG  
2821 N N   . ARG A 330 ? 0.60700 0.39985 0.63723 0.05313  0.11811  0.08229  330 ARG A N   
2822 C CA  . ARG A 330 ? 0.64391 0.44832 0.66061 -0.05389 0.11642  0.10940  330 ARG A CA  
2823 C C   . ARG A 330 ? 0.62704 0.45149 0.65411 -0.04411 0.08911  0.08310  330 ARG A C   
2824 O O   . ARG A 330 ? 0.69410 0.46823 0.64347 -0.10479 0.10354  0.07654  330 ARG A O   
2825 C CB  . ARG A 330 ? 0.59762 0.41021 0.65237 0.05365  0.10704  0.04733  330 ARG A CB  
2826 C CG  . ARG A 330 ? 0.60353 0.42498 0.61124 -0.05168 0.08952  0.01844  330 ARG A CG  
2827 C CD  . ARG A 330 ? 0.55960 0.49838 0.55376 -0.03983 0.09560  0.00930  330 ARG A CD  
2828 N NE  . ARG A 330 ? 0.48809 0.57122 0.53674 0.09493  0.04208  -0.03329 330 ARG A NE  
2829 C CZ  . ARG A 330 ? 0.46773 0.54850 0.46491 0.03674  0.06879  -0.05981 330 ARG A CZ  
2830 N NH1 . ARG A 330 ? 0.51564 0.48938 0.43922 -0.04259 0.05975  0.05860  330 ARG A NH1 
2831 N NH2 . ARG A 330 ? 0.36565 0.63288 0.36576 0.04995  0.00084  -0.14129 330 ARG A NH2 
2832 N N   . ASP A 331 ? 0.52674 0.43060 0.66092 0.02771  -0.01451 0.12656  331 ASP A N   
2833 C CA  . ASP A 331 ? 0.53816 0.41677 0.64406 0.02086  -0.01317 0.09909  331 ASP A CA  
2834 C C   . ASP A 331 ? 0.50368 0.42330 0.59167 -0.09127 0.04860  0.05513  331 ASP A C   
2835 O O   . ASP A 331 ? 0.57350 0.43488 0.60197 -0.09351 0.12024  0.03908  331 ASP A O   
2836 C CB  . ASP A 331 ? 0.72430 0.48881 0.69842 -0.00411 -0.06056 0.17302  331 ASP A CB  
2837 C CG  . ASP A 331 ? 1.08360 0.59929 0.77102 -0.08831 -0.02080 0.20699  331 ASP A CG  
2838 O OD1 . ASP A 331 ? 1.16124 0.64223 0.79026 -0.14371 -0.02746 0.19988  331 ASP A OD1 
2839 O OD2 . ASP A 331 ? 1.22653 0.63483 0.78449 -0.04657 -0.03611 0.24308  331 ASP A OD2 
2840 N N   . LEU A 332 ? 0.50409 0.43466 0.52868 -0.12211 0.02174  -0.00829 332 LEU A N   
2841 C CA  . LEU A 332 ? 0.49250 0.41224 0.46201 -0.02288 0.04168  -0.07877 332 LEU A CA  
2842 C C   . LEU A 332 ? 0.52804 0.43501 0.46902 0.02511  0.04895  -0.08118 332 LEU A C   
2843 O O   . LEU A 332 ? 0.55499 0.46062 0.50111 0.06885  0.01131  -0.04934 332 LEU A O   
2844 C CB  . LEU A 332 ? 0.54340 0.32259 0.42218 0.01197  0.06781  -0.11997 332 LEU A CB  
2845 C CG  . LEU A 332 ? 0.45365 0.32117 0.38450 -0.10158 0.04802  -0.12360 332 LEU A CG  
2846 C CD1 . LEU A 332 ? 0.56621 0.31258 0.37115 -0.06149 -0.01695 -0.09496 332 LEU A CD1 
2847 C CD2 . LEU A 332 ? 0.36663 0.46213 0.39921 -0.13932 0.03300  -0.05070 332 LEU A CD2 
2848 N N   . LEU A 333 ? 0.46314 0.43417 0.44567 -0.07550 0.00334  -0.04660 333 LEU A N   
2849 C CA  . LEU A 333 ? 0.47147 0.42677 0.47704 -0.08928 0.04558  -0.05924 333 LEU A CA  
2850 C C   . LEU A 333 ? 0.46023 0.49939 0.42464 -0.08198 0.06332  -0.02705 333 LEU A C   
2851 O O   . LEU A 333 ? 0.62811 0.51178 0.38906 -0.03619 0.02917  -0.05587 333 LEU A O   
2852 C CB  . LEU A 333 ? 0.49889 0.43401 0.52303 -0.05991 0.05289  -0.11122 333 LEU A CB  
2853 C CG  . LEU A 333 ? 0.55575 0.50920 0.58599 -0.06418 -0.00148 -0.13105 333 LEU A CG  
2854 C CD1 . LEU A 333 ? 0.60708 0.56850 0.57119 -0.06318 -0.03367 -0.08811 333 LEU A CD1 
2855 C CD2 . LEU A 333 ? 0.66979 0.46609 0.65672 -0.05508 -0.00622 -0.13393 333 LEU A CD2 
2856 N N   . ILE A 334 ? 0.53809 0.52432 0.40479 -0.06206 0.12247  -0.02780 334 ILE A N   
2857 C CA  . ILE A 334 ? 0.48378 0.63378 0.41639 -0.07327 0.10848  -0.05998 334 ILE A CA  
2858 C C   . ILE A 334 ? 0.45953 0.61052 0.41938 -0.10542 0.09967  -0.07740 334 ILE A C   
2859 O O   . ILE A 334 ? 0.50224 0.59854 0.43691 -0.10659 0.10451  -0.11094 334 ILE A O   
2860 C CB  . ILE A 334 ? 0.59955 0.65985 0.43169 0.00498  0.16784  -0.09588 334 ILE A CB  
2861 C CG1 . ILE A 334 ? 0.72490 0.64994 0.48295 0.01311  0.15861  -0.13539 334 ILE A CG1 
2862 C CG2 . ILE A 334 ? 0.66131 0.68277 0.38661 -0.09486 0.18917  -0.07276 334 ILE A CG2 
2863 C CD1 . ILE A 334 ? 0.74351 0.64553 0.48197 -0.09672 0.16323  -0.14197 334 ILE A CD1 
2864 N N   . ASP A 335 ? 0.45286 0.63196 0.42130 -0.14092 0.04935  -0.05739 335 ASP A N   
2865 C CA  . ASP A 335 ? 0.50951 0.64626 0.41577 -0.06061 0.08985  -0.06902 335 ASP A CA  
2866 C C   . ASP A 335 ? 0.54226 0.56454 0.38917 -0.06289 0.04592  0.00192  335 ASP A C   
2867 O O   . ASP A 335 ? 0.59165 0.52993 0.35053 -0.10171 0.02932  0.04335  335 ASP A O   
2868 C CB  . ASP A 335 ? 0.73685 0.75913 0.43578 0.00333  0.02172  -0.10387 335 ASP A CB  
2869 C CG  . ASP A 335 ? 0.94363 0.87284 0.52425 0.06697  -0.02511 -0.11604 335 ASP A CG  
2870 O OD1 . ASP A 335 ? 0.92535 0.93281 0.48841 0.02336  0.02847  -0.10801 335 ASP A OD1 
2871 O OD2 . ASP A 335 ? 1.07668 0.88194 0.55898 0.08667  -0.09575 -0.11039 335 ASP A OD2 
2872 N N   . GLU A 336 ? 0.52498 0.44323 0.34915 -0.07580 0.09434  0.00144  336 GLU A N   
2873 C CA  . GLU A 336 ? 0.49702 0.45852 0.35353 -0.12210 0.05781  0.04200  336 GLU A CA  
2874 C C   . GLU A 336 ? 0.50120 0.45747 0.37170 -0.12567 0.00995  0.02037  336 GLU A C   
2875 O O   . GLU A 336 ? 0.42693 0.45533 0.42113 -0.05003 0.01870  0.03236  336 GLU A O   
2876 C CB  . GLU A 336 ? 0.59004 0.44412 0.37983 -0.01979 0.02179  0.01752  336 GLU A CB  
2877 C CG  . GLU A 336 ? 0.59490 0.43871 0.43351 -0.09058 0.02142  0.02558  336 GLU A CG  
2878 C CD  . GLU A 336 ? 0.55082 0.51506 0.47164 -0.04883 0.02156  0.01605  336 GLU A CD  
2879 O OE1 . GLU A 336 ? 0.48986 0.46123 0.51453 -0.03407 0.01838  0.06291  336 GLU A OE1 
2880 O OE2 . GLU A 336 ? 0.58217 0.51441 0.44972 -0.10596 -0.03937 0.04493  336 GLU A OE2 
2881 N N   . TRP A 337 ? 0.52004 0.44826 0.37451 -0.10185 0.05013  -0.03685 337 TRP A N   
2882 C CA  . TRP A 337 ? 0.45670 0.43145 0.38824 -0.09044 0.01036  -0.00816 337 TRP A CA  
2883 C C   . TRP A 337 ? 0.50002 0.37236 0.37603 -0.09574 0.03300  -0.03108 337 TRP A C   
2884 O O   . TRP A 337 ? 0.40460 0.35573 0.35757 -0.01933 0.03007  -0.00405 337 TRP A O   
2885 C CB  . TRP A 337 ? 0.45612 0.43792 0.39696 -0.03072 0.04010  -0.02156 337 TRP A CB  
2886 C CG  . TRP A 337 ? 0.40880 0.36200 0.40435 -0.01103 0.05656  0.02136  337 TRP A CG  
2887 C CD1 . TRP A 337 ? 0.36619 0.38502 0.41402 0.00468  0.09691  0.01555  337 TRP A CD1 
2888 C CD2 . TRP A 337 ? 0.37425 0.35891 0.42672 0.00931  0.05007  0.00248  337 TRP A CD2 
2889 N NE1 . TRP A 337 ? 0.36503 0.38999 0.43101 0.00154  0.09322  -0.03230 337 TRP A NE1 
2890 C CE2 . TRP A 337 ? 0.38540 0.36748 0.42918 0.02358  0.06016  -0.06282 337 TRP A CE2 
2891 C CE3 . TRP A 337 ? 0.46785 0.33606 0.45220 0.01403  0.07510  0.02462  337 TRP A CE3 
2892 C CZ2 . TRP A 337 ? 0.42284 0.36033 0.46243 -0.02435 0.07235  -0.02667 337 TRP A CZ2 
2893 C CZ3 . TRP A 337 ? 0.45102 0.32292 0.46843 -0.02682 0.07934  0.05259  337 TRP A CZ3 
2894 C CH2 . TRP A 337 ? 0.41158 0.33333 0.45707 0.03143  0.07374  0.02123  337 TRP A CH2 
2895 N N   . LYS A 338 ? 0.48154 0.38513 0.33025 -0.06209 0.02613  0.04791  338 LYS A N   
2896 C CA  . LYS A 338 ? 0.51502 0.47330 0.34523 -0.05829 0.03044  0.01435  338 LYS A CA  
2897 C C   . LYS A 338 ? 0.43629 0.47318 0.36014 -0.08519 0.02897  0.02048  338 LYS A C   
2898 O O   . LYS A 338 ? 0.48916 0.45603 0.38953 -0.07973 0.01208  0.02056  338 LYS A O   
2899 C CB  . LYS A 338 ? 0.63036 0.51087 0.33237 -0.17196 0.04555  -0.02198 338 LYS A CB  
2900 C CG  . LYS A 338 ? 0.65321 0.59476 0.37953 -0.19452 0.15456  -0.04843 338 LYS A CG  
2901 C CD  . LYS A 338 ? 0.68875 0.62116 0.38820 -0.12407 0.02692  -0.09509 338 LYS A CD  
2902 C CE  . LYS A 338 ? 0.81342 0.64028 0.43773 -0.12738 0.00668  -0.07521 338 LYS A CE  
2903 N NZ  . LYS A 338 ? 0.86389 0.58969 0.44296 -0.20339 -0.00033 -0.11574 338 LYS A NZ  
2904 N N   . SER A 339 ? 0.49019 0.45792 0.36962 -0.15387 0.04278  0.04797  339 SER A N   
2905 C CA  . SER A 339 ? 0.53595 0.52819 0.37401 -0.10687 0.02973  0.02761  339 SER A CA  
2906 C C   . SER A 339 ? 0.48534 0.46667 0.41255 -0.09938 -0.05125 0.01935  339 SER A C   
2907 O O   . SER A 339 ? 0.43474 0.42202 0.43061 -0.01835 -0.00936 0.04984  339 SER A O   
2908 C CB  . SER A 339 ? 0.55150 0.51220 0.42782 -0.12838 0.00884  0.00432  339 SER A CB  
2909 O OG  . SER A 339 ? 0.52708 0.55988 0.45419 -0.07820 -0.02837 0.04286  339 SER A OG  
2910 N N   . LEU A 340 ? 0.41608 0.44106 0.39416 -0.13155 -0.05364 0.04247  340 LEU A N   
2911 C CA  . LEU A 340 ? 0.42941 0.41399 0.38998 -0.10443 -0.04148 0.05701  340 LEU A CA  
2912 C C   . LEU A 340 ? 0.40090 0.44180 0.38601 -0.02241 -0.01346 0.07537  340 LEU A C   
2913 O O   . LEU A 340 ? 0.33433 0.41887 0.38093 0.03179  0.03974  0.01572  340 LEU A O   
2914 C CB  . LEU A 340 ? 0.34823 0.40747 0.39215 -0.05954 0.06815  0.09253  340 LEU A CB  
2915 C CG  . LEU A 340 ? 0.39405 0.41346 0.44989 -0.03618 0.08698  0.08622  340 LEU A CG  
2916 C CD1 . LEU A 340 ? 0.45579 0.37651 0.45681 -0.08502 0.01184  0.10248  340 LEU A CD1 
2917 C CD2 . LEU A 340 ? 0.53956 0.47215 0.48940 -0.03739 0.10361  0.14407  340 LEU A CD2 
2918 N N   . THR A 341 ? 0.34360 0.43918 0.37460 -0.10095 0.00893  0.10822  341 THR A N   
2919 C CA  . THR A 341 ? 0.29421 0.42689 0.40792 -0.08977 0.01490  0.05847  341 THR A CA  
2920 C C   . THR A 341 ? 0.34667 0.44414 0.39431 -0.04892 0.00555  0.06856  341 THR A C   
2921 O O   . THR A 341 ? 0.37234 0.48027 0.39738 -0.04342 0.02439  0.10648  341 THR A O   
2922 C CB  . THR A 341 ? 0.34987 0.36895 0.45181 -0.08966 0.04213  0.06475  341 THR A CB  
2923 O OG1 . THR A 341 ? 0.45293 0.33258 0.46393 0.01171  0.01881  0.00794  341 THR A OG1 
2924 C CG2 . THR A 341 ? 0.43979 0.36993 0.40656 -0.10410 0.01655  0.04900  341 THR A CG2 
2925 N N   . TYR A 342 ? 0.40543 0.39701 0.40066 0.00418  -0.06662 0.03373  342 TYR A N   
2926 C CA  . TYR A 342 ? 0.37422 0.46058 0.41638 -0.03709 0.01275  0.05176  342 TYR A CA  
2927 C C   . TYR A 342 ? 0.39973 0.50414 0.44965 -0.04903 -0.00098 0.08466  342 TYR A C   
2928 O O   . TYR A 342 ? 0.42127 0.56015 0.45269 -0.04693 -0.00753 0.11393  342 TYR A O   
2929 C CB  . TYR A 342 ? 0.38128 0.44351 0.39608 -0.05012 -0.01357 0.03180  342 TYR A CB  
2930 C CG  . TYR A 342 ? 0.42665 0.47719 0.41745 -0.07739 -0.02138 0.02457  342 TYR A CG  
2931 C CD1 . TYR A 342 ? 0.36142 0.49818 0.42218 -0.09684 -0.01573 0.06256  342 TYR A CD1 
2932 C CD2 . TYR A 342 ? 0.42406 0.51092 0.44019 -0.04612 0.00129  0.06968  342 TYR A CD2 
2933 C CE1 . TYR A 342 ? 0.43460 0.54205 0.44503 0.00049  -0.06791 0.10418  342 TYR A CE1 
2934 C CE2 . TYR A 342 ? 0.48585 0.55988 0.45422 -0.03468 -0.03779 0.11696  342 TYR A CE2 
2935 C CZ  . TYR A 342 ? 0.44553 0.56987 0.44813 -0.03639 -0.11541 0.14131  342 TYR A CZ  
2936 O OH  . TYR A 342 ? 0.45617 0.57474 0.50882 -0.06244 -0.11471 0.14111  342 TYR A OH  
2937 N N   . ASP A 343 ? 0.34150 0.46084 0.43380 -0.03265 0.01712  0.07153  343 ASP A N   
2938 C CA  . ASP A 343 ? 0.30022 0.50876 0.46825 -0.08476 -0.00516 0.06784  343 ASP A CA  
2939 C C   . ASP A 343 ? 0.37389 0.50519 0.44744 -0.05576 0.00847  0.08271  343 ASP A C   
2940 O O   . ASP A 343 ? 0.34749 0.46654 0.45991 -0.02911 -0.02715 0.09938  343 ASP A O   
2941 C CB  . ASP A 343 ? 0.30395 0.49652 0.49013 -0.08865 0.02143  0.08581  343 ASP A CB  
2942 C CG  . ASP A 343 ? 0.49248 0.57525 0.57081 -0.01812 0.08865  0.04572  343 ASP A CG  
2943 O OD1 . ASP A 343 ? 0.47669 0.62313 0.62234 0.03796  0.03712  0.03570  343 ASP A OD1 
2944 O OD2 . ASP A 343 ? 0.62611 0.58053 0.62321 -0.04143 0.14736  -0.00483 343 ASP A OD2 
2945 N N   . GLU A 344 ? 0.31542 0.49164 0.39808 -0.05463 -0.02650 0.07890  344 GLU A N   
2946 C CA  . GLU A 344 ? 0.27723 0.46272 0.39268 0.01143  -0.02915 0.09040  344 GLU A CA  
2947 C C   . GLU A 344 ? 0.41066 0.45131 0.39588 -0.00803 0.01839  0.10351  344 GLU A C   
2948 O O   . GLU A 344 ? 0.33301 0.44916 0.42021 -0.00371 0.01628  0.08374  344 GLU A O   
2949 C CB  . GLU A 344 ? 0.39492 0.42761 0.35053 0.00692  -0.06443 0.04824  344 GLU A CB  
2950 C CG  . GLU A 344 ? 0.36033 0.44289 0.34054 -0.07900 0.03974  0.03941  344 GLU A CG  
2951 C CD  . GLU A 344 ? 0.38819 0.44270 0.39889 -0.05109 0.04104  0.05110  344 GLU A CD  
2952 O OE1 . GLU A 344 ? 0.43462 0.48901 0.37260 0.00537  0.00342  0.00497  344 GLU A OE1 
2953 O OE2 . GLU A 344 ? 0.49674 0.41643 0.44200 -0.06112 0.11664  0.01125  344 GLU A OE2 
2954 N N   . VAL A 345 ? 0.43626 0.43746 0.33568 0.02843  0.01986  0.09007  345 VAL A N   
2955 C CA  . VAL A 345 ? 0.47780 0.42273 0.36934 -0.01315 -0.03098 0.07828  345 VAL A CA  
2956 C C   . VAL A 345 ? 0.37641 0.44105 0.42455 -0.03045 -0.05096 0.08731  345 VAL A C   
2957 O O   . VAL A 345 ? 0.44248 0.40372 0.41313 -0.00887 0.00227  0.08131  345 VAL A O   
2958 C CB  . VAL A 345 ? 0.49569 0.42102 0.33085 -0.02392 -0.04648 0.11670  345 VAL A CB  
2959 C CG1 . VAL A 345 ? 0.43688 0.35482 0.38547 0.02485  -0.04926 0.11656  345 VAL A CG1 
2960 C CG2 . VAL A 345 ? 0.45646 0.45763 0.34668 -0.13592 -0.01924 0.06574  345 VAL A CG2 
2961 N N   . ILE A 346 ? 0.31052 0.46778 0.44769 0.01696  -0.06953 0.06519  346 ILE A N   
2962 C CA  . ILE A 346 ? 0.33255 0.51892 0.50796 0.03926  -0.09737 0.01630  346 ILE A CA  
2963 C C   . ILE A 346 ? 0.37951 0.49835 0.52406 0.09203  -0.08227 -0.00652 346 ILE A C   
2964 O O   . ILE A 346 ? 0.47203 0.52334 0.57661 0.17919  -0.09185 -0.03503 346 ILE A O   
2965 C CB  . ILE A 346 ? 0.52846 0.64340 0.57863 0.07734  -0.08942 0.00470  346 ILE A CB  
2966 C CG1 . ILE A 346 ? 0.72345 0.79422 0.63553 0.15407  -0.06328 -0.01809 346 ILE A CG1 
2967 C CG2 . ILE A 346 ? 0.48514 0.64100 0.59264 0.05576  -0.09353 -0.05471 346 ILE A CG2 
2968 C CD1 . ILE A 346 ? 0.89004 0.86639 0.67021 0.27235  -0.03361 -0.03145 346 ILE A CD1 
2969 N N   . SER A 347 ? 0.31471 0.45271 0.47564 0.00980  -0.03225 -0.01616 347 SER A N   
2970 C CA  . SER A 347 ? 0.38001 0.47406 0.47893 0.01915  0.00590  0.04164  347 SER A CA  
2971 C C   . SER A 347 ? 0.38137 0.49609 0.49929 0.02428  0.03806  0.02479  347 SER A C   
2972 O O   . SER A 347 ? 0.35104 0.52374 0.51100 0.03876  0.05823  0.00829  347 SER A O   
2973 C CB  . SER A 347 ? 0.47905 0.49603 0.43284 0.01205  -0.00706 0.09653  347 SER A CB  
2974 O OG  . SER A 347 ? 0.50633 0.55990 0.39327 -0.02853 0.02977  0.08262  347 SER A OG  
2975 N N   . PHE A 348 ? 0.34028 0.48946 0.50705 -0.02668 0.03528  0.04415  348 PHE A N   
2976 C CA  . PHE A 348 ? 0.23738 0.40104 0.50223 0.01413  0.06127  0.03907  348 PHE A CA  
2977 C C   . PHE A 348 ? 0.40657 0.39480 0.51950 0.02469  -0.00947 0.03309  348 PHE A C   
2978 O O   . PHE A 348 ? 0.41905 0.40632 0.51993 0.00210  -0.00264 0.08504  348 PHE A O   
2979 C CB  . PHE A 348 ? 0.21953 0.39045 0.50199 -0.01644 0.03590  0.02257  348 PHE A CB  
2980 C CG  . PHE A 348 ? 0.28113 0.39867 0.45725 0.00139  -0.01178 0.04739  348 PHE A CG  
2981 C CD1 . PHE A 348 ? 0.34160 0.43446 0.45209 0.07176  0.03192  -0.00464 348 PHE A CD1 
2982 C CD2 . PHE A 348 ? 0.46305 0.42486 0.45154 0.02364  0.00205  0.04640  348 PHE A CD2 
2983 C CE1 . PHE A 348 ? 0.40058 0.42209 0.45995 0.03982  0.02708  0.00362  348 PHE A CE1 
2984 C CE2 . PHE A 348 ? 0.42915 0.36809 0.45153 0.05602  0.03230  0.03994  348 PHE A CE2 
2985 C CZ  . PHE A 348 ? 0.41219 0.39785 0.47092 0.02390  0.05993  0.02619  348 PHE A CZ  
2986 N N   . VAL A 349 ? 0.39520 0.36035 0.55898 -0.01391 -0.00551 0.01977  349 VAL A N   
2987 C CA  . VAL A 349 ? 0.33599 0.38330 0.58473 0.00020  0.05269  0.00366  349 VAL A CA  
2988 C C   . VAL A 349 ? 0.35821 0.38899 0.57217 0.00251  0.00258  0.01665  349 VAL A C   
2989 O O   . VAL A 349 ? 0.46867 0.37008 0.55099 0.10469  0.06660  0.03241  349 VAL A O   
2990 C CB  . VAL A 349 ? 0.49261 0.42487 0.63927 0.05913  0.07576  0.05309  349 VAL A CB  
2991 C CG1 . VAL A 349 ? 0.53450 0.48780 0.65280 0.15530  0.03937  0.06756  349 VAL A CG1 
2992 C CG2 . VAL A 349 ? 0.51291 0.48538 0.66686 0.05605  0.03234  0.03193  349 VAL A CG2 
2993 N N   . PRO A 350 ? 0.51596 0.39814 0.58718 0.07984  -0.00877 0.05232  350 PRO A N   
2994 C CA  . PRO A 350 ? 0.58646 0.41650 0.59075 0.03110  -0.01435 0.05715  350 PRO A CA  
2995 C C   . PRO A 350 ? 0.52900 0.43171 0.63970 0.07223  -0.01123 0.03936  350 PRO A C   
2996 O O   . PRO A 350 ? 0.62674 0.40319 0.63946 0.08220  0.02473  0.00134  350 PRO A O   
2997 C CB  . PRO A 350 ? 0.70388 0.48616 0.56508 -0.05900 -0.00945 0.07393  350 PRO A CB  
2998 C CG  . PRO A 350 ? 0.68663 0.52481 0.57258 0.07660  -0.00380 0.09213  350 PRO A CG  
2999 C CD  . PRO A 350 ? 0.63181 0.45881 0.56789 0.12071  -0.06377 0.09506  350 PRO A CD  
3000 N N   . PRO A 351 ? 0.45225 0.49204 0.69374 -0.03800 -0.07804 0.00034  351 PRO A N   
3001 C CA  . PRO A 351 ? 0.58061 0.52470 0.76766 0.01153  -0.07756 -0.01053 351 PRO A CA  
3002 C C   . PRO A 351 ? 0.74802 0.60215 0.82982 0.03809  -0.07058 -0.02697 351 PRO A C   
3003 O O   . PRO A 351 ? 0.71461 0.57114 0.80432 -0.06777 -0.08676 -0.01700 351 PRO A O   
3004 C CB  . PRO A 351 ? 0.59420 0.52693 0.75152 -0.06092 -0.09017 0.01062  351 PRO A CB  
3005 C CG  . PRO A 351 ? 0.54217 0.49572 0.70816 -0.06713 -0.09840 -0.00579 351 PRO A CG  
3006 C CD  . PRO A 351 ? 0.40752 0.48530 0.69401 -0.01506 -0.06639 -0.01688 351 PRO A CD  
3007 N N   . PRO A 352 ? 0.83143 0.71909 0.88858 0.14205  0.02156  -0.02075 352 PRO A N   
3008 C CA  . PRO A 352 ? 0.89518 0.81725 0.93482 0.12404  0.03249  0.00346  352 PRO A CA  
3009 C C   . PRO A 352 ? 1.00225 0.87843 0.97089 -0.00900 -0.00757 0.02508  352 PRO A C   
3010 O O   . PRO A 352 ? 0.95910 0.87036 0.97172 -0.04127 -0.02646 -0.02842 352 PRO A O   
3011 C CB  . PRO A 352 ? 0.94356 0.80656 0.92266 0.15987  0.07584  -0.00679 352 PRO A CB  
3012 C CG  . PRO A 352 ? 0.94546 0.81677 0.90435 0.19121  0.08074  0.00456  352 PRO A CG  
3013 C CD  . PRO A 352 ? 0.86971 0.73486 0.89538 0.20117  0.08428  0.00949  352 PRO A CD  
3014 N N   . LEU A 353 ? 1.08203 0.95548 0.99394 -0.02296 0.00658  0.04019  353 LEU A N   
3015 C CA  . LEU A 353 ? 1.02747 1.01070 1.00087 0.01657  0.04979  0.08070  353 LEU A CA  
3016 C C   . LEU A 353 ? 0.99856 1.03110 1.03025 0.03939  -0.01593 0.12536  353 LEU A C   
3017 O O   . LEU A 353 ? 0.96130 1.04557 1.04529 0.10294  -0.02876 0.15947  353 LEU A O   
3018 C CB  . LEU A 353 ? 1.03303 0.98661 0.98878 0.06637  0.10870  0.05699  353 LEU A CB  
3019 C CG  . LEU A 353 ? 0.93401 0.97356 0.96766 0.09756  0.16281  0.03437  353 LEU A CG  
3020 C CD1 . LEU A 353 ? 0.94361 0.95156 0.95768 0.13609  0.20156  0.02719  353 LEU A CD1 
3021 C CD2 . LEU A 353 ? 0.86013 0.95586 0.95563 0.06699  0.20437  0.02114  353 LEU A CD2 
3022 C C01 . 6GI B .   ? 1.38736 1.33092 1.53083 0.13348  0.19628  0.21308  401 6GI A C01 
3023 C C02 . 6GI B .   ? 1.25627 1.29580 1.52638 0.22057  0.23277  0.20834  401 6GI A C02 
3024 C C03 . 6GI B .   ? 1.14178 1.31075 1.51984 0.23570  0.26447  0.20682  401 6GI A C03 
3025 C C04 . 6GI B .   ? 1.13406 1.31767 1.51585 0.18534  0.26201  0.21593  401 6GI A C04 
3026 C C05 . 6GI B .   ? 1.29047 1.32664 1.52319 0.09372  0.20687  0.23481  401 6GI A C05 
3027 C C08 . 6GI B .   ? 1.32555 1.34244 1.52913 0.05815  0.10180  0.21850  401 6GI A C08 
3028 C C09 . 6GI B .   ? 1.39337 1.33366 1.53713 0.08213  0.12084  0.22736  401 6GI A C09 
3029 C C10 . 6GI B .   ? 1.27378 1.37701 1.52111 0.05593  0.01412  0.17742  401 6GI A C10 
3030 C C12 . 6GI B .   ? 1.31631 1.46188 1.49073 0.02515  -0.05411 0.07332  401 6GI A C12 
3031 C C13 . 6GI B .   ? 1.29498 1.46793 1.47731 0.02133  -0.08568 0.03518  401 6GI A C13 
3032 C C14 . 6GI B .   ? 1.30519 1.49132 1.46430 0.03438  -0.07571 0.00642  401 6GI A C14 
3033 C C15 . 6GI B .   ? 1.37833 1.52379 1.45307 0.05658  -0.06490 -0.01519 401 6GI A C15 
3034 C C16 . 6GI B .   ? 1.35687 1.49888 1.46569 -0.00938 -0.07104 0.00672  401 6GI A C16 
3035 C C17 . 6GI B .   ? 1.34666 1.48064 1.47880 -0.00089 -0.06550 0.04038  401 6GI A C17 
3036 C C18 . 6GI B .   ? 1.50216 1.56012 1.42814 0.19705  -0.05752 -0.06072 401 6GI A C18 
3037 C C20 . 6GI B .   ? 1.55131 1.57825 1.40749 0.37422  -0.05283 -0.08603 401 6GI A C20 
3038 C C22 . 6GI B .   ? 1.59091 1.58694 1.41385 0.23319  -0.01330 -0.09382 401 6GI A C22 
3039 C C25 . 6GI B .   ? 1.62025 1.54599 1.39919 0.39131  -0.09479 -0.08028 401 6GI A C25 
3040 C C26 . 6GI B .   ? 1.70609 1.54073 1.39339 0.41338  -0.09878 -0.08636 401 6GI A C26 
3041 C C28 . 6GI B .   ? 1.58007 1.52455 1.39421 0.37463  -0.11431 -0.07397 401 6GI A C28 
3042 C C29 . 6GI B .   ? 1.53487 1.48872 1.38642 0.32345  -0.12120 -0.07017 401 6GI A C29 
3043 C C30 . 6GI B .   ? 1.54156 1.49421 1.38017 0.32513  -0.10442 -0.05917 401 6GI A C30 
3044 C C31 . 6GI B .   ? 1.67392 1.51644 1.38135 0.39919  -0.09809 -0.07509 401 6GI A C31 
3045 C C33 . 6GI B .   ? 1.38268 1.45173 1.36374 0.14413  -0.11620 -0.05703 401 6GI A C33 
3046 C C34 . 6GI B .   ? 1.30939 1.44688 1.35837 0.09947  -0.13372 -0.05045 401 6GI A C34 
3047 C C35 . 6GI B .   ? 1.31717 1.45242 1.37160 0.15151  -0.13487 -0.04150 401 6GI A C35 
3048 N N06 . 6GI B .   ? 1.40979 1.34030 1.53332 0.09628  0.16157  0.22818  401 6GI A N06 
3049 N N07 . 6GI B .   ? 1.30382 1.33684 1.52365 0.04454  0.16865  0.24376  401 6GI A N07 
3050 N N19 . 6GI B .   ? 1.54177 1.56463 1.41246 0.34140  -0.06265 -0.07538 401 6GI A N19 
3051 N N21 . 6GI B .   ? 1.50498 1.58140 1.40836 0.32942  -0.03278 -0.08903 401 6GI A N21 
3052 N N23 . 6GI B .   ? 1.57748 1.57941 1.41923 0.20579  -0.03382 -0.08881 401 6GI A N23 
3053 N N24 . 6GI B .   ? 1.66641 1.60322 1.41690 0.18914  -0.00068 -0.09397 401 6GI A N24 
3054 N N27 . 6GI B .   ? 1.67971 1.57208 1.40161 0.41517  -0.09034 -0.09138 401 6GI A N27 
3055 O O11 . 6GI B .   ? 1.29460 1.42432 1.51024 0.04699  -0.03967 0.13505  401 6GI A O11 
3056 O O32 . 6GI B .   ? 1.46855 1.47327 1.38020 0.23886  -0.11224 -0.06894 401 6GI A O32 
3057 O O36 . 6GI B .   ? 1.40229 1.48098 1.38005 0.22623  -0.12488 -0.03390 401 6GI A O36 
3080 C C1  . GOL C .   ? 0.40439 0.77663 0.51321 0.15398  -0.07919 0.07744  402 GOL A C1  
3081 O O1  . GOL C .   ? 0.68281 0.69936 0.44110 0.25186  -0.07684 0.03497  402 GOL A O1  
3082 C C2  . GOL C .   ? 0.58007 0.83495 0.55300 -0.02926 0.04616  0.06012  402 GOL A C2  
3083 O O2  . GOL C .   ? 0.51066 0.79569 0.58735 -0.19421 0.09219  0.13291  402 GOL A O2  
3084 C C3  . GOL C .   ? 0.49729 0.79541 0.53486 -0.10847 0.04756  0.00789  402 GOL A C3  
3085 O O3  . GOL C .   ? 0.41570 0.76541 0.52072 0.02655  0.04487  0.05922  402 GOL A O3  
3094 C C1  . GOL D .   ? 0.91759 0.77686 0.85150 -0.03633 -0.09309 -0.13320 403 GOL A C1  
3095 O O1  . GOL D .   ? 0.80447 0.70352 0.84153 -0.10001 -0.16279 -0.15127 403 GOL A O1  
3096 C C2  . GOL D .   ? 0.75815 0.79624 0.83260 -0.02563 -0.05988 -0.11612 403 GOL A C2  
3097 O O2  . GOL D .   ? 0.63369 0.76828 0.80547 0.13737  -0.12351 -0.16253 403 GOL A O2  
3098 C C3  . GOL D .   ? 0.63051 0.78503 0.81846 -0.01254 0.02174  -0.01981 403 GOL A C3  
3099 O O3  . GOL D .   ? 0.37204 0.68747 0.78719 0.06021  -0.00356 0.02284  403 GOL A O3  
3108 C C1  . GOL E .   ? 0.85706 1.20911 1.14911 0.08298  0.35613  -0.08374 404 GOL A C1  
3109 O O1  . GOL E .   ? 0.69977 1.18087 1.15663 0.03367  0.29722  -0.07678 404 GOL A O1  
3110 C C2  . GOL E .   ? 1.03138 1.23101 1.13861 0.05612  0.42809  -0.09481 404 GOL A C2  
3111 O O2  . GOL E .   ? 1.11576 1.23452 1.12567 0.04914  0.38726  -0.11989 404 GOL A O2  
3112 C C3  . GOL E .   ? 0.98694 1.25664 1.12557 0.01168  0.55661  -0.08932 404 GOL A C3  
3113 O O3  . GOL E .   ? 0.99831 1.25183 1.12924 -0.05437 0.61799  -0.07065 404 GOL A O3  
3122 C C1  . GOL F .   ? 1.12039 1.05016 1.33151 0.38019  -0.10301 -0.08476 405 GOL A C1  
3123 O O1  . GOL F .   ? 1.06361 1.02048 1.33348 0.36237  -0.12124 -0.06909 405 GOL A O1  
3124 C C2  . GOL F .   ? 1.18224 1.08609 1.33107 0.38935  -0.08387 -0.09756 405 GOL A C2  
3125 O O2  . GOL F .   ? 1.16453 1.10654 1.34190 0.37667  -0.03895 -0.11019 405 GOL A O2  
3126 C C3  . GOL F .   ? 1.21541 1.07076 1.32561 0.48463  -0.10296 -0.09339 405 GOL A C3  
3127 O O3  . GOL F .   ? 1.10075 1.05064 1.32031 0.62592  -0.17820 -0.07918 405 GOL A O3  
3136 C C1  . GOL G .   ? 0.75956 0.85521 0.94537 0.00451  0.19424  -0.07448 406 GOL A C1  
3137 O O1  . GOL G .   ? 0.76317 0.73328 0.88459 -0.15943 0.14060  -0.14913 406 GOL A O1  
3138 C C2  . GOL G .   ? 0.82374 0.86645 1.00197 0.06635  0.21643  -0.08216 406 GOL A C2  
3139 O O2  . GOL G .   ? 0.81629 0.85388 1.01067 0.02713  0.25065  -0.07427 406 GOL A O2  
3140 C C3  . GOL G .   ? 0.95317 0.89087 1.05402 0.07543  0.17684  -0.09965 406 GOL A C3  
3141 O O3  . GOL G .   ? 1.04320 0.93355 1.08078 0.00235  0.14342  -0.07843 406 GOL A O3  
# 
