data_8Y5Z
# 
_entry.id   8Y5Z 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Y5Z         pdb_00008y5z 10.2210/pdb8y5z/pdb 
WWPDB D_1300044952 ?            ?                   
EMDB  EMD-38960    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Y5Z 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'human NaS1 inward state' 
_pdbx_database_related.db_id          EMD-38960 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhang.ss@phytovent.com 
_pdbx_contact_author.name_first         Sensen 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8827-3959 
# 
_audit_author.name               'Zhang, S.S.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0001-8827-3959 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Sci Adv' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2375-2548 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            10 
_citation.language                  ? 
_citation.page_first                eado6778 
_citation.page_last                 eado6778 
_citation.title                     
'Structural basis for the reaction cycle and transport mechanism of human Na + -sulfate cotransporter NaS1 (SLC13A1).' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/sciadv.ado6778 
_citation.pdbx_database_id_PubMed   39576865 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chen, X.'  1  0000-0002-2989-5608 
primary 'Zhang, Y.' 2  0009-0002-4992-8750 
primary 'Yin, J.'   3  0000-0002-2251-8674 
primary 'Liu, C.'   4  ?                   
primary 'Xie, M.'   5  0000-0001-5659-7211 
primary 'Wang, Y.'  6  0000-0001-5254-5940 
primary 'Chen, M.'  7  0009-0004-3038-9587 
primary 'Zhang, R.' 8  0009-0005-1071-4079 
primary 'Yuan, X.'  9  0009-0007-3574-8018 
primary 'Li, D.'    10 0009-0003-1748-6449 
primary 'Chen, X.'  11 0000-0001-8774-6021 
primary 'Gao, X.'   12 0000-0002-7108-3574 
primary 'Cai, G.'   13 0000-0001-8586-6353 
primary 'Zhang, S.' 14 0000-0001-8827-3959 
primary 'Zhou, B.'  15 0000-0001-8207-7367 
primary 'Yang, M.'  16 0000-0002-6798-3094 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Solute carrier family 13 member 1' 66184.859 2 ? ? ? ? 
2 non-polymer syn 'SULFATE ION'                       96.063    2 ? ? ? ? 
3 non-polymer syn 'SODIUM ION'                        22.990    2 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Renal sodium/sulfate cotransporter,Na(+)/sulfate cotransporter,hNaSi-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASA
YFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIIN
AEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT
CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGK
TKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIP
AKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM
VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIV
GVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASA
YFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIIN
AEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT
CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGK
TKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIP
AKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM
VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIV
GVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP
;
_entity_poly.pdbx_strand_id                 B,A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SULFATE ION' SO4 
3 'SODIUM ION'  NA  
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   PHE n 
1 4   PHE n 
1 5   SER n 
1 6   TYR n 
1 7   ILE n 
1 8   LEU n 
1 9   VAL n 
1 10  TYR n 
1 11  ARG n 
1 12  ARG n 
1 13  PHE n 
1 14  LEU n 
1 15  PHE n 
1 16  VAL n 
1 17  VAL n 
1 18  PHE n 
1 19  THR n 
1 20  VAL n 
1 21  LEU n 
1 22  VAL n 
1 23  LEU n 
1 24  LEU n 
1 25  PRO n 
1 26  LEU n 
1 27  PRO n 
1 28  ILE n 
1 29  VAL n 
1 30  LEU n 
1 31  HIS n 
1 32  THR n 
1 33  LYS n 
1 34  GLU n 
1 35  ALA n 
1 36  GLU n 
1 37  CYS n 
1 38  ALA n 
1 39  TYR n 
1 40  THR n 
1 41  LEU n 
1 42  PHE n 
1 43  VAL n 
1 44  VAL n 
1 45  ALA n 
1 46  THR n 
1 47  PHE n 
1 48  TRP n 
1 49  LEU n 
1 50  THR n 
1 51  GLU n 
1 52  ALA n 
1 53  LEU n 
1 54  PRO n 
1 55  LEU n 
1 56  SER n 
1 57  VAL n 
1 58  THR n 
1 59  ALA n 
1 60  LEU n 
1 61  LEU n 
1 62  PRO n 
1 63  SER n 
1 64  LEU n 
1 65  MET n 
1 66  LEU n 
1 67  PRO n 
1 68  MET n 
1 69  PHE n 
1 70  GLY n 
1 71  ILE n 
1 72  MET n 
1 73  PRO n 
1 74  SER n 
1 75  LYS n 
1 76  LYS n 
1 77  VAL n 
1 78  ALA n 
1 79  SER n 
1 80  ALA n 
1 81  TYR n 
1 82  PHE n 
1 83  LYS n 
1 84  ASP n 
1 85  PHE n 
1 86  HIS n 
1 87  LEU n 
1 88  LEU n 
1 89  LEU n 
1 90  ILE n 
1 91  GLY n 
1 92  VAL n 
1 93  ILE n 
1 94  CYS n 
1 95  LEU n 
1 96  ALA n 
1 97  THR n 
1 98  SER n 
1 99  ILE n 
1 100 GLU n 
1 101 LYS n 
1 102 TRP n 
1 103 ASN n 
1 104 LEU n 
1 105 HIS n 
1 106 LYS n 
1 107 ARG n 
1 108 ILE n 
1 109 ALA n 
1 110 LEU n 
1 111 LYS n 
1 112 MET n 
1 113 VAL n 
1 114 MET n 
1 115 MET n 
1 116 VAL n 
1 117 GLY n 
1 118 VAL n 
1 119 ASN n 
1 120 PRO n 
1 121 ALA n 
1 122 TRP n 
1 123 LEU n 
1 124 THR n 
1 125 LEU n 
1 126 GLY n 
1 127 PHE n 
1 128 MET n 
1 129 SER n 
1 130 SER n 
1 131 THR n 
1 132 ALA n 
1 133 PHE n 
1 134 LEU n 
1 135 SER n 
1 136 MET n 
1 137 TRP n 
1 138 LEU n 
1 139 SER n 
1 140 ASN n 
1 141 THR n 
1 142 SER n 
1 143 THR n 
1 144 ALA n 
1 145 ALA n 
1 146 MET n 
1 147 VAL n 
1 148 MET n 
1 149 PRO n 
1 150 ILE n 
1 151 ALA n 
1 152 GLU n 
1 153 ALA n 
1 154 VAL n 
1 155 VAL n 
1 156 GLN n 
1 157 GLN n 
1 158 ILE n 
1 159 ILE n 
1 160 ASN n 
1 161 ALA n 
1 162 GLU n 
1 163 ALA n 
1 164 GLU n 
1 165 VAL n 
1 166 GLU n 
1 167 ALA n 
1 168 THR n 
1 169 GLN n 
1 170 MET n 
1 171 THR n 
1 172 TYR n 
1 173 PHE n 
1 174 ASN n 
1 175 GLY n 
1 176 SER n 
1 177 THR n 
1 178 ASN n 
1 179 HIS n 
1 180 GLY n 
1 181 LEU n 
1 182 GLU n 
1 183 ILE n 
1 184 ASP n 
1 185 GLU n 
1 186 SER n 
1 187 VAL n 
1 188 ASN n 
1 189 GLY n 
1 190 HIS n 
1 191 GLU n 
1 192 ILE n 
1 193 ASN n 
1 194 GLU n 
1 195 ARG n 
1 196 LYS n 
1 197 GLU n 
1 198 LYS n 
1 199 THR n 
1 200 LYS n 
1 201 PRO n 
1 202 VAL n 
1 203 PRO n 
1 204 GLY n 
1 205 TYR n 
1 206 ASN n 
1 207 ASN n 
1 208 ASP n 
1 209 THR n 
1 210 GLY n 
1 211 LYS n 
1 212 ILE n 
1 213 SER n 
1 214 SER n 
1 215 LYS n 
1 216 VAL n 
1 217 GLU n 
1 218 LEU n 
1 219 GLU n 
1 220 LYS n 
1 221 ASN n 
1 222 SER n 
1 223 GLY n 
1 224 MET n 
1 225 ARG n 
1 226 THR n 
1 227 LYS n 
1 228 TYR n 
1 229 ARG n 
1 230 THR n 
1 231 LYS n 
1 232 LYS n 
1 233 GLY n 
1 234 HIS n 
1 235 VAL n 
1 236 THR n 
1 237 ARG n 
1 238 LYS n 
1 239 LEU n 
1 240 THR n 
1 241 CYS n 
1 242 LEU n 
1 243 CYS n 
1 244 ILE n 
1 245 ALA n 
1 246 TYR n 
1 247 SER n 
1 248 SER n 
1 249 THR n 
1 250 ILE n 
1 251 GLY n 
1 252 GLY n 
1 253 LEU n 
1 254 THR n 
1 255 THR n 
1 256 ILE n 
1 257 THR n 
1 258 GLY n 
1 259 THR n 
1 260 SER n 
1 261 THR n 
1 262 ASN n 
1 263 LEU n 
1 264 ILE n 
1 265 PHE n 
1 266 ALA n 
1 267 GLU n 
1 268 TYR n 
1 269 PHE n 
1 270 ASN n 
1 271 THR n 
1 272 ARG n 
1 273 TYR n 
1 274 PRO n 
1 275 ASP n 
1 276 CYS n 
1 277 ARG n 
1 278 CYS n 
1 279 LEU n 
1 280 ASN n 
1 281 PHE n 
1 282 GLY n 
1 283 SER n 
1 284 TRP n 
1 285 PHE n 
1 286 THR n 
1 287 PHE n 
1 288 SER n 
1 289 PHE n 
1 290 PRO n 
1 291 ALA n 
1 292 ALA n 
1 293 LEU n 
1 294 ILE n 
1 295 ILE n 
1 296 LEU n 
1 297 LEU n 
1 298 LEU n 
1 299 SER n 
1 300 TRP n 
1 301 ILE n 
1 302 TRP n 
1 303 LEU n 
1 304 GLN n 
1 305 TRP n 
1 306 LEU n 
1 307 PHE n 
1 308 LEU n 
1 309 GLY n 
1 310 PHE n 
1 311 ASN n 
1 312 PHE n 
1 313 LYS n 
1 314 GLU n 
1 315 MET n 
1 316 PHE n 
1 317 LYS n 
1 318 CYS n 
1 319 GLY n 
1 320 LYS n 
1 321 THR n 
1 322 LYS n 
1 323 THR n 
1 324 VAL n 
1 325 GLN n 
1 326 GLN n 
1 327 LYS n 
1 328 ALA n 
1 329 CYS n 
1 330 ALA n 
1 331 GLU n 
1 332 VAL n 
1 333 ILE n 
1 334 LYS n 
1 335 GLN n 
1 336 GLU n 
1 337 TYR n 
1 338 GLN n 
1 339 LYS n 
1 340 LEU n 
1 341 GLY n 
1 342 PRO n 
1 343 ILE n 
1 344 ARG n 
1 345 TYR n 
1 346 GLN n 
1 347 GLU n 
1 348 ILE n 
1 349 VAL n 
1 350 THR n 
1 351 LEU n 
1 352 VAL n 
1 353 LEU n 
1 354 PHE n 
1 355 ILE n 
1 356 ILE n 
1 357 MET n 
1 358 ALA n 
1 359 LEU n 
1 360 LEU n 
1 361 TRP n 
1 362 PHE n 
1 363 SER n 
1 364 ARG n 
1 365 ASP n 
1 366 PRO n 
1 367 GLY n 
1 368 PHE n 
1 369 VAL n 
1 370 PRO n 
1 371 GLY n 
1 372 TRP n 
1 373 SER n 
1 374 ALA n 
1 375 LEU n 
1 376 PHE n 
1 377 SER n 
1 378 GLU n 
1 379 TYR n 
1 380 PRO n 
1 381 GLY n 
1 382 PHE n 
1 383 ALA n 
1 384 THR n 
1 385 ASP n 
1 386 SER n 
1 387 THR n 
1 388 VAL n 
1 389 ALA n 
1 390 LEU n 
1 391 LEU n 
1 392 ILE n 
1 393 GLY n 
1 394 LEU n 
1 395 LEU n 
1 396 PHE n 
1 397 PHE n 
1 398 LEU n 
1 399 ILE n 
1 400 PRO n 
1 401 ALA n 
1 402 LYS n 
1 403 THR n 
1 404 LEU n 
1 405 THR n 
1 406 LYS n 
1 407 THR n 
1 408 THR n 
1 409 PRO n 
1 410 THR n 
1 411 GLY n 
1 412 GLU n 
1 413 ILE n 
1 414 VAL n 
1 415 ALA n 
1 416 PHE n 
1 417 ASP n 
1 418 TYR n 
1 419 SER n 
1 420 PRO n 
1 421 LEU n 
1 422 ILE n 
1 423 THR n 
1 424 TRP n 
1 425 LYS n 
1 426 GLU n 
1 427 PHE n 
1 428 GLN n 
1 429 SER n 
1 430 PHE n 
1 431 MET n 
1 432 PRO n 
1 433 TRP n 
1 434 ASP n 
1 435 ILE n 
1 436 ALA n 
1 437 ILE n 
1 438 LEU n 
1 439 VAL n 
1 440 GLY n 
1 441 GLY n 
1 442 GLY n 
1 443 PHE n 
1 444 ALA n 
1 445 LEU n 
1 446 ALA n 
1 447 ASP n 
1 448 GLY n 
1 449 CYS n 
1 450 GLU n 
1 451 GLU n 
1 452 SER n 
1 453 GLY n 
1 454 LEU n 
1 455 SER n 
1 456 LYS n 
1 457 TRP n 
1 458 ILE n 
1 459 GLY n 
1 460 ASN n 
1 461 LYS n 
1 462 LEU n 
1 463 SER n 
1 464 PRO n 
1 465 LEU n 
1 466 GLY n 
1 467 SER n 
1 468 LEU n 
1 469 PRO n 
1 470 ALA n 
1 471 TRP n 
1 472 LEU n 
1 473 ILE n 
1 474 ILE n 
1 475 LEU n 
1 476 ILE n 
1 477 SER n 
1 478 SER n 
1 479 LEU n 
1 480 MET n 
1 481 VAL n 
1 482 THR n 
1 483 SER n 
1 484 LEU n 
1 485 THR n 
1 486 GLU n 
1 487 VAL n 
1 488 ALA n 
1 489 SER n 
1 490 ASN n 
1 491 PRO n 
1 492 ALA n 
1 493 THR n 
1 494 ILE n 
1 495 THR n 
1 496 LEU n 
1 497 PHE n 
1 498 LEU n 
1 499 PRO n 
1 500 ILE n 
1 501 LEU n 
1 502 SER n 
1 503 PRO n 
1 504 LEU n 
1 505 ALA n 
1 506 GLU n 
1 507 ALA n 
1 508 ILE n 
1 509 HIS n 
1 510 VAL n 
1 511 ASN n 
1 512 PRO n 
1 513 LEU n 
1 514 TYR n 
1 515 ILE n 
1 516 LEU n 
1 517 ILE n 
1 518 PRO n 
1 519 SER n 
1 520 THR n 
1 521 LEU n 
1 522 CYS n 
1 523 THR n 
1 524 SER n 
1 525 PHE n 
1 526 ALA n 
1 527 PHE n 
1 528 LEU n 
1 529 LEU n 
1 530 PRO n 
1 531 VAL n 
1 532 ALA n 
1 533 ASN n 
1 534 PRO n 
1 535 PRO n 
1 536 ASN n 
1 537 ALA n 
1 538 ILE n 
1 539 VAL n 
1 540 PHE n 
1 541 SER n 
1 542 TYR n 
1 543 GLY n 
1 544 HIS n 
1 545 LEU n 
1 546 LYS n 
1 547 VAL n 
1 548 ILE n 
1 549 ASP n 
1 550 MET n 
1 551 VAL n 
1 552 LYS n 
1 553 ALA n 
1 554 GLY n 
1 555 LEU n 
1 556 GLY n 
1 557 VAL n 
1 558 ASN n 
1 559 ILE n 
1 560 VAL n 
1 561 GLY n 
1 562 VAL n 
1 563 ALA n 
1 564 VAL n 
1 565 VAL n 
1 566 MET n 
1 567 LEU n 
1 568 GLY n 
1 569 ILE n 
1 570 CYS n 
1 571 THR n 
1 572 TRP n 
1 573 ILE n 
1 574 VAL n 
1 575 PRO n 
1 576 MET n 
1 577 PHE n 
1 578 ASP n 
1 579 LEU n 
1 580 TYR n 
1 581 THR n 
1 582 TYR n 
1 583 PRO n 
1 584 SER n 
1 585 TRP n 
1 586 ALA n 
1 587 PRO n 
1 588 ALA n 
1 589 MET n 
1 590 SER n 
1 591 ASN n 
1 592 GLU n 
1 593 THR n 
1 594 MET n 
1 595 PRO n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   595 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'SLC13A1, NAS1, NASI1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            HEK293F 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
NA  non-polymer         . 'SODIUM ION'    ? 'Na 1'           22.990  
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   B . n 
A 1 2   LYS 2   2   2   LYS LYS B . n 
A 1 3   PHE 3   3   3   PHE PHE B . n 
A 1 4   PHE 4   4   4   PHE PHE B . n 
A 1 5   SER 5   5   5   SER SER B . n 
A 1 6   TYR 6   6   6   TYR TYR B . n 
A 1 7   ILE 7   7   7   ILE ILE B . n 
A 1 8   LEU 8   8   8   LEU LEU B . n 
A 1 9   VAL 9   9   9   VAL VAL B . n 
A 1 10  TYR 10  10  10  TYR TYR B . n 
A 1 11  ARG 11  11  11  ARG ARG B . n 
A 1 12  ARG 12  12  12  ARG ARG B . n 
A 1 13  PHE 13  13  13  PHE PHE B . n 
A 1 14  LEU 14  14  14  LEU LEU B . n 
A 1 15  PHE 15  15  15  PHE PHE B . n 
A 1 16  VAL 16  16  16  VAL VAL B . n 
A 1 17  VAL 17  17  17  VAL VAL B . n 
A 1 18  PHE 18  18  18  PHE PHE B . n 
A 1 19  THR 19  19  19  THR THR B . n 
A 1 20  VAL 20  20  20  VAL VAL B . n 
A 1 21  LEU 21  21  21  LEU LEU B . n 
A 1 22  VAL 22  22  22  VAL VAL B . n 
A 1 23  LEU 23  23  23  LEU LEU B . n 
A 1 24  LEU 24  24  24  LEU LEU B . n 
A 1 25  PRO 25  25  25  PRO PRO B . n 
A 1 26  LEU 26  26  26  LEU LEU B . n 
A 1 27  PRO 27  27  27  PRO PRO B . n 
A 1 28  ILE 28  28  28  ILE ILE B . n 
A 1 29  VAL 29  29  29  VAL VAL B . n 
A 1 30  LEU 30  30  30  LEU LEU B . n 
A 1 31  HIS 31  31  31  HIS HIS B . n 
A 1 32  THR 32  32  32  THR THR B . n 
A 1 33  LYS 33  33  33  LYS LYS B . n 
A 1 34  GLU 34  34  34  GLU GLU B . n 
A 1 35  ALA 35  35  35  ALA ALA B . n 
A 1 36  GLU 36  36  36  GLU GLU B . n 
A 1 37  CYS 37  37  37  CYS CYS B . n 
A 1 38  ALA 38  38  38  ALA ALA B . n 
A 1 39  TYR 39  39  39  TYR TYR B . n 
A 1 40  THR 40  40  40  THR THR B . n 
A 1 41  LEU 41  41  41  LEU LEU B . n 
A 1 42  PHE 42  42  42  PHE PHE B . n 
A 1 43  VAL 43  43  43  VAL VAL B . n 
A 1 44  VAL 44  44  44  VAL VAL B . n 
A 1 45  ALA 45  45  45  ALA ALA B . n 
A 1 46  THR 46  46  46  THR THR B . n 
A 1 47  PHE 47  47  47  PHE PHE B . n 
A 1 48  TRP 48  48  48  TRP TRP B . n 
A 1 49  LEU 49  49  49  LEU LEU B . n 
A 1 50  THR 50  50  50  THR THR B . n 
A 1 51  GLU 51  51  51  GLU GLU B . n 
A 1 52  ALA 52  52  52  ALA ALA B . n 
A 1 53  LEU 53  53  53  LEU LEU B . n 
A 1 54  PRO 54  54  54  PRO PRO B . n 
A 1 55  LEU 55  55  55  LEU LEU B . n 
A 1 56  SER 56  56  56  SER SER B . n 
A 1 57  VAL 57  57  57  VAL VAL B . n 
A 1 58  THR 58  58  58  THR THR B . n 
A 1 59  ALA 59  59  59  ALA ALA B . n 
A 1 60  LEU 60  60  60  LEU LEU B . n 
A 1 61  LEU 61  61  61  LEU LEU B . n 
A 1 62  PRO 62  62  62  PRO PRO B . n 
A 1 63  SER 63  63  63  SER SER B . n 
A 1 64  LEU 64  64  64  LEU LEU B . n 
A 1 65  MET 65  65  65  MET MET B . n 
A 1 66  LEU 66  66  66  LEU LEU B . n 
A 1 67  PRO 67  67  67  PRO PRO B . n 
A 1 68  MET 68  68  68  MET MET B . n 
A 1 69  PHE 69  69  69  PHE PHE B . n 
A 1 70  GLY 70  70  70  GLY GLY B . n 
A 1 71  ILE 71  71  71  ILE ILE B . n 
A 1 72  MET 72  72  72  MET MET B . n 
A 1 73  PRO 73  73  73  PRO PRO B . n 
A 1 74  SER 74  74  74  SER SER B . n 
A 1 75  LYS 75  75  75  LYS LYS B . n 
A 1 76  LYS 76  76  76  LYS LYS B . n 
A 1 77  VAL 77  77  77  VAL VAL B . n 
A 1 78  ALA 78  78  78  ALA ALA B . n 
A 1 79  SER 79  79  79  SER SER B . n 
A 1 80  ALA 80  80  80  ALA ALA B . n 
A 1 81  TYR 81  81  81  TYR TYR B . n 
A 1 82  PHE 82  82  82  PHE PHE B . n 
A 1 83  LYS 83  83  83  LYS LYS B . n 
A 1 84  ASP 84  84  84  ASP ASP B . n 
A 1 85  PHE 85  85  85  PHE PHE B . n 
A 1 86  HIS 86  86  86  HIS HIS B . n 
A 1 87  LEU 87  87  87  LEU LEU B . n 
A 1 88  LEU 88  88  88  LEU LEU B . n 
A 1 89  LEU 89  89  89  LEU LEU B . n 
A 1 90  ILE 90  90  90  ILE ILE B . n 
A 1 91  GLY 91  91  91  GLY GLY B . n 
A 1 92  VAL 92  92  92  VAL VAL B . n 
A 1 93  ILE 93  93  93  ILE ILE B . n 
A 1 94  CYS 94  94  94  CYS CYS B . n 
A 1 95  LEU 95  95  95  LEU LEU B . n 
A 1 96  ALA 96  96  96  ALA ALA B . n 
A 1 97  THR 97  97  97  THR THR B . n 
A 1 98  SER 98  98  98  SER SER B . n 
A 1 99  ILE 99  99  99  ILE ILE B . n 
A 1 100 GLU 100 100 100 GLU GLU B . n 
A 1 101 LYS 101 101 101 LYS LYS B . n 
A 1 102 TRP 102 102 102 TRP TRP B . n 
A 1 103 ASN 103 103 103 ASN ASN B . n 
A 1 104 LEU 104 104 104 LEU LEU B . n 
A 1 105 HIS 105 105 105 HIS HIS B . n 
A 1 106 LYS 106 106 106 LYS LYS B . n 
A 1 107 ARG 107 107 107 ARG ARG B . n 
A 1 108 ILE 108 108 108 ILE ILE B . n 
A 1 109 ALA 109 109 109 ALA ALA B . n 
A 1 110 LEU 110 110 110 LEU LEU B . n 
A 1 111 LYS 111 111 111 LYS LYS B . n 
A 1 112 MET 112 112 112 MET MET B . n 
A 1 113 VAL 113 113 113 VAL VAL B . n 
A 1 114 MET 114 114 114 MET MET B . n 
A 1 115 MET 115 115 115 MET MET B . n 
A 1 116 VAL 116 116 116 VAL VAL B . n 
A 1 117 GLY 117 117 117 GLY GLY B . n 
A 1 118 VAL 118 118 118 VAL VAL B . n 
A 1 119 ASN 119 119 119 ASN ASN B . n 
A 1 120 PRO 120 120 120 PRO PRO B . n 
A 1 121 ALA 121 121 121 ALA ALA B . n 
A 1 122 TRP 122 122 122 TRP TRP B . n 
A 1 123 LEU 123 123 123 LEU LEU B . n 
A 1 124 THR 124 124 124 THR THR B . n 
A 1 125 LEU 125 125 125 LEU LEU B . n 
A 1 126 GLY 126 126 126 GLY GLY B . n 
A 1 127 PHE 127 127 127 PHE PHE B . n 
A 1 128 MET 128 128 128 MET MET B . n 
A 1 129 SER 129 129 129 SER SER B . n 
A 1 130 SER 130 130 130 SER SER B . n 
A 1 131 THR 131 131 131 THR THR B . n 
A 1 132 ALA 132 132 132 ALA ALA B . n 
A 1 133 PHE 133 133 133 PHE PHE B . n 
A 1 134 LEU 134 134 134 LEU LEU B . n 
A 1 135 SER 135 135 135 SER SER B . n 
A 1 136 MET 136 136 136 MET MET B . n 
A 1 137 TRP 137 137 137 TRP TRP B . n 
A 1 138 LEU 138 138 138 LEU LEU B . n 
A 1 139 SER 139 139 139 SER SER B . n 
A 1 140 ASN 140 140 140 ASN ASN B . n 
A 1 141 THR 141 141 141 THR THR B . n 
A 1 142 SER 142 142 142 SER SER B . n 
A 1 143 THR 143 143 143 THR THR B . n 
A 1 144 ALA 144 144 144 ALA ALA B . n 
A 1 145 ALA 145 145 145 ALA ALA B . n 
A 1 146 MET 146 146 146 MET MET B . n 
A 1 147 VAL 147 147 147 VAL VAL B . n 
A 1 148 MET 148 148 148 MET MET B . n 
A 1 149 PRO 149 149 149 PRO PRO B . n 
A 1 150 ILE 150 150 150 ILE ILE B . n 
A 1 151 ALA 151 151 151 ALA ALA B . n 
A 1 152 GLU 152 152 152 GLU GLU B . n 
A 1 153 ALA 153 153 153 ALA ALA B . n 
A 1 154 VAL 154 154 154 VAL VAL B . n 
A 1 155 VAL 155 155 155 VAL VAL B . n 
A 1 156 GLN 156 156 156 GLN GLN B . n 
A 1 157 GLN 157 157 157 GLN GLN B . n 
A 1 158 ILE 158 158 158 ILE ILE B . n 
A 1 159 ILE 159 159 159 ILE ILE B . n 
A 1 160 ASN 160 160 160 ASN ASN B . n 
A 1 161 ALA 161 161 161 ALA ALA B . n 
A 1 162 GLU 162 162 ?   ?   ?   B . n 
A 1 163 ALA 163 163 ?   ?   ?   B . n 
A 1 164 GLU 164 164 ?   ?   ?   B . n 
A 1 165 VAL 165 165 ?   ?   ?   B . n 
A 1 166 GLU 166 166 ?   ?   ?   B . n 
A 1 167 ALA 167 167 ?   ?   ?   B . n 
A 1 168 THR 168 168 ?   ?   ?   B . n 
A 1 169 GLN 169 169 ?   ?   ?   B . n 
A 1 170 MET 170 170 ?   ?   ?   B . n 
A 1 171 THR 171 171 ?   ?   ?   B . n 
A 1 172 TYR 172 172 ?   ?   ?   B . n 
A 1 173 PHE 173 173 ?   ?   ?   B . n 
A 1 174 ASN 174 174 ?   ?   ?   B . n 
A 1 175 GLY 175 175 ?   ?   ?   B . n 
A 1 176 SER 176 176 ?   ?   ?   B . n 
A 1 177 THR 177 177 ?   ?   ?   B . n 
A 1 178 ASN 178 178 ?   ?   ?   B . n 
A 1 179 HIS 179 179 ?   ?   ?   B . n 
A 1 180 GLY 180 180 ?   ?   ?   B . n 
A 1 181 LEU 181 181 ?   ?   ?   B . n 
A 1 182 GLU 182 182 ?   ?   ?   B . n 
A 1 183 ILE 183 183 ?   ?   ?   B . n 
A 1 184 ASP 184 184 ?   ?   ?   B . n 
A 1 185 GLU 185 185 ?   ?   ?   B . n 
A 1 186 SER 186 186 ?   ?   ?   B . n 
A 1 187 VAL 187 187 ?   ?   ?   B . n 
A 1 188 ASN 188 188 ?   ?   ?   B . n 
A 1 189 GLY 189 189 ?   ?   ?   B . n 
A 1 190 HIS 190 190 ?   ?   ?   B . n 
A 1 191 GLU 191 191 ?   ?   ?   B . n 
A 1 192 ILE 192 192 ?   ?   ?   B . n 
A 1 193 ASN 193 193 ?   ?   ?   B . n 
A 1 194 GLU 194 194 ?   ?   ?   B . n 
A 1 195 ARG 195 195 ?   ?   ?   B . n 
A 1 196 LYS 196 196 ?   ?   ?   B . n 
A 1 197 GLU 197 197 ?   ?   ?   B . n 
A 1 198 LYS 198 198 ?   ?   ?   B . n 
A 1 199 THR 199 199 ?   ?   ?   B . n 
A 1 200 LYS 200 200 ?   ?   ?   B . n 
A 1 201 PRO 201 201 ?   ?   ?   B . n 
A 1 202 VAL 202 202 ?   ?   ?   B . n 
A 1 203 PRO 203 203 ?   ?   ?   B . n 
A 1 204 GLY 204 204 ?   ?   ?   B . n 
A 1 205 TYR 205 205 ?   ?   ?   B . n 
A 1 206 ASN 206 206 ?   ?   ?   B . n 
A 1 207 ASN 207 207 ?   ?   ?   B . n 
A 1 208 ASP 208 208 ?   ?   ?   B . n 
A 1 209 THR 209 209 ?   ?   ?   B . n 
A 1 210 GLY 210 210 ?   ?   ?   B . n 
A 1 211 LYS 211 211 ?   ?   ?   B . n 
A 1 212 ILE 212 212 ?   ?   ?   B . n 
A 1 213 SER 213 213 ?   ?   ?   B . n 
A 1 214 SER 214 214 ?   ?   ?   B . n 
A 1 215 LYS 215 215 ?   ?   ?   B . n 
A 1 216 VAL 216 216 ?   ?   ?   B . n 
A 1 217 GLU 217 217 ?   ?   ?   B . n 
A 1 218 LEU 218 218 ?   ?   ?   B . n 
A 1 219 GLU 219 219 ?   ?   ?   B . n 
A 1 220 LYS 220 220 ?   ?   ?   B . n 
A 1 221 ASN 221 221 ?   ?   ?   B . n 
A 1 222 SER 222 222 ?   ?   ?   B . n 
A 1 223 GLY 223 223 ?   ?   ?   B . n 
A 1 224 MET 224 224 ?   ?   ?   B . n 
A 1 225 ARG 225 225 ?   ?   ?   B . n 
A 1 226 THR 226 226 ?   ?   ?   B . n 
A 1 227 LYS 227 227 ?   ?   ?   B . n 
A 1 228 TYR 228 228 ?   ?   ?   B . n 
A 1 229 ARG 229 229 ?   ?   ?   B . n 
A 1 230 THR 230 230 230 THR THR B . n 
A 1 231 LYS 231 231 231 LYS LYS B . n 
A 1 232 LYS 232 232 232 LYS LYS B . n 
A 1 233 GLY 233 233 233 GLY GLY B . n 
A 1 234 HIS 234 234 234 HIS HIS B . n 
A 1 235 VAL 235 235 235 VAL VAL B . n 
A 1 236 THR 236 236 236 THR THR B . n 
A 1 237 ARG 237 237 237 ARG ARG B . n 
A 1 238 LYS 238 238 238 LYS LYS B . n 
A 1 239 LEU 239 239 239 LEU LEU B . n 
A 1 240 THR 240 240 240 THR THR B . n 
A 1 241 CYS 241 241 241 CYS CYS B . n 
A 1 242 LEU 242 242 242 LEU LEU B . n 
A 1 243 CYS 243 243 243 CYS CYS B . n 
A 1 244 ILE 244 244 244 ILE ILE B . n 
A 1 245 ALA 245 245 245 ALA ALA B . n 
A 1 246 TYR 246 246 246 TYR TYR B . n 
A 1 247 SER 247 247 247 SER SER B . n 
A 1 248 SER 248 248 248 SER SER B . n 
A 1 249 THR 249 249 249 THR THR B . n 
A 1 250 ILE 250 250 250 ILE ILE B . n 
A 1 251 GLY 251 251 251 GLY GLY B . n 
A 1 252 GLY 252 252 252 GLY GLY B . n 
A 1 253 LEU 253 253 253 LEU LEU B . n 
A 1 254 THR 254 254 254 THR THR B . n 
A 1 255 THR 255 255 255 THR THR B . n 
A 1 256 ILE 256 256 256 ILE ILE B . n 
A 1 257 THR 257 257 257 THR THR B . n 
A 1 258 GLY 258 258 258 GLY GLY B . n 
A 1 259 THR 259 259 259 THR THR B . n 
A 1 260 SER 260 260 260 SER SER B . n 
A 1 261 THR 261 261 261 THR THR B . n 
A 1 262 ASN 262 262 262 ASN ASN B . n 
A 1 263 LEU 263 263 263 LEU LEU B . n 
A 1 264 ILE 264 264 264 ILE ILE B . n 
A 1 265 PHE 265 265 265 PHE PHE B . n 
A 1 266 ALA 266 266 266 ALA ALA B . n 
A 1 267 GLU 267 267 267 GLU GLU B . n 
A 1 268 TYR 268 268 268 TYR TYR B . n 
A 1 269 PHE 269 269 269 PHE PHE B . n 
A 1 270 ASN 270 270 270 ASN ASN B . n 
A 1 271 THR 271 271 271 THR THR B . n 
A 1 272 ARG 272 272 272 ARG ARG B . n 
A 1 273 TYR 273 273 273 TYR TYR B . n 
A 1 274 PRO 274 274 274 PRO PRO B . n 
A 1 275 ASP 275 275 275 ASP ASP B . n 
A 1 276 CYS 276 276 276 CYS CYS B . n 
A 1 277 ARG 277 277 277 ARG ARG B . n 
A 1 278 CYS 278 278 278 CYS CYS B . n 
A 1 279 LEU 279 279 279 LEU LEU B . n 
A 1 280 ASN 280 280 280 ASN ASN B . n 
A 1 281 PHE 281 281 281 PHE PHE B . n 
A 1 282 GLY 282 282 282 GLY GLY B . n 
A 1 283 SER 283 283 283 SER SER B . n 
A 1 284 TRP 284 284 284 TRP TRP B . n 
A 1 285 PHE 285 285 285 PHE PHE B . n 
A 1 286 THR 286 286 286 THR THR B . n 
A 1 287 PHE 287 287 287 PHE PHE B . n 
A 1 288 SER 288 288 288 SER SER B . n 
A 1 289 PHE 289 289 289 PHE PHE B . n 
A 1 290 PRO 290 290 290 PRO PRO B . n 
A 1 291 ALA 291 291 291 ALA ALA B . n 
A 1 292 ALA 292 292 292 ALA ALA B . n 
A 1 293 LEU 293 293 293 LEU LEU B . n 
A 1 294 ILE 294 294 294 ILE ILE B . n 
A 1 295 ILE 295 295 295 ILE ILE B . n 
A 1 296 LEU 296 296 296 LEU LEU B . n 
A 1 297 LEU 297 297 297 LEU LEU B . n 
A 1 298 LEU 298 298 298 LEU LEU B . n 
A 1 299 SER 299 299 299 SER SER B . n 
A 1 300 TRP 300 300 300 TRP TRP B . n 
A 1 301 ILE 301 301 301 ILE ILE B . n 
A 1 302 TRP 302 302 302 TRP TRP B . n 
A 1 303 LEU 303 303 303 LEU LEU B . n 
A 1 304 GLN 304 304 304 GLN GLN B . n 
A 1 305 TRP 305 305 305 TRP TRP B . n 
A 1 306 LEU 306 306 306 LEU LEU B . n 
A 1 307 PHE 307 307 307 PHE PHE B . n 
A 1 308 LEU 308 308 308 LEU LEU B . n 
A 1 309 GLY 309 309 309 GLY GLY B . n 
A 1 310 PHE 310 310 310 PHE PHE B . n 
A 1 311 ASN 311 311 311 ASN ASN B . n 
A 1 312 PHE 312 312 312 PHE PHE B . n 
A 1 313 LYS 313 313 313 LYS LYS B . n 
A 1 314 GLU 314 314 314 GLU GLU B . n 
A 1 315 MET 315 315 315 MET MET B . n 
A 1 316 PHE 316 316 316 PHE PHE B . n 
A 1 317 LYS 317 317 ?   ?   ?   B . n 
A 1 318 CYS 318 318 ?   ?   ?   B . n 
A 1 319 GLY 319 319 ?   ?   ?   B . n 
A 1 320 LYS 320 320 ?   ?   ?   B . n 
A 1 321 THR 321 321 321 THR THR B . n 
A 1 322 LYS 322 322 322 LYS LYS B . n 
A 1 323 THR 323 323 323 THR THR B . n 
A 1 324 VAL 324 324 324 VAL VAL B . n 
A 1 325 GLN 325 325 325 GLN GLN B . n 
A 1 326 GLN 326 326 326 GLN GLN B . n 
A 1 327 LYS 327 327 327 LYS LYS B . n 
A 1 328 ALA 328 328 328 ALA ALA B . n 
A 1 329 CYS 329 329 329 CYS CYS B . n 
A 1 330 ALA 330 330 330 ALA ALA B . n 
A 1 331 GLU 331 331 331 GLU GLU B . n 
A 1 332 VAL 332 332 332 VAL VAL B . n 
A 1 333 ILE 333 333 333 ILE ILE B . n 
A 1 334 LYS 334 334 334 LYS LYS B . n 
A 1 335 GLN 335 335 335 GLN GLN B . n 
A 1 336 GLU 336 336 336 GLU GLU B . n 
A 1 337 TYR 337 337 337 TYR TYR B . n 
A 1 338 GLN 338 338 338 GLN GLN B . n 
A 1 339 LYS 339 339 339 LYS LYS B . n 
A 1 340 LEU 340 340 340 LEU LEU B . n 
A 1 341 GLY 341 341 341 GLY GLY B . n 
A 1 342 PRO 342 342 342 PRO PRO B . n 
A 1 343 ILE 343 343 343 ILE ILE B . n 
A 1 344 ARG 344 344 344 ARG ARG B . n 
A 1 345 TYR 345 345 345 TYR TYR B . n 
A 1 346 GLN 346 346 346 GLN GLN B . n 
A 1 347 GLU 347 347 347 GLU GLU B . n 
A 1 348 ILE 348 348 348 ILE ILE B . n 
A 1 349 VAL 349 349 349 VAL VAL B . n 
A 1 350 THR 350 350 350 THR THR B . n 
A 1 351 LEU 351 351 351 LEU LEU B . n 
A 1 352 VAL 352 352 352 VAL VAL B . n 
A 1 353 LEU 353 353 353 LEU LEU B . n 
A 1 354 PHE 354 354 354 PHE PHE B . n 
A 1 355 ILE 355 355 355 ILE ILE B . n 
A 1 356 ILE 356 356 356 ILE ILE B . n 
A 1 357 MET 357 357 357 MET MET B . n 
A 1 358 ALA 358 358 358 ALA ALA B . n 
A 1 359 LEU 359 359 359 LEU LEU B . n 
A 1 360 LEU 360 360 360 LEU LEU B . n 
A 1 361 TRP 361 361 361 TRP TRP B . n 
A 1 362 PHE 362 362 362 PHE PHE B . n 
A 1 363 SER 363 363 363 SER SER B . n 
A 1 364 ARG 364 364 364 ARG ARG B . n 
A 1 365 ASP 365 365 365 ASP ASP B . n 
A 1 366 PRO 366 366 366 PRO PRO B . n 
A 1 367 GLY 367 367 367 GLY GLY B . n 
A 1 368 PHE 368 368 368 PHE PHE B . n 
A 1 369 VAL 369 369 369 VAL VAL B . n 
A 1 370 PRO 370 370 370 PRO PRO B . n 
A 1 371 GLY 371 371 371 GLY GLY B . n 
A 1 372 TRP 372 372 372 TRP TRP B . n 
A 1 373 SER 373 373 373 SER SER B . n 
A 1 374 ALA 374 374 374 ALA ALA B . n 
A 1 375 LEU 375 375 375 LEU LEU B . n 
A 1 376 PHE 376 376 376 PHE PHE B . n 
A 1 377 SER 377 377 377 SER SER B . n 
A 1 378 GLU 378 378 378 GLU GLU B . n 
A 1 379 TYR 379 379 379 TYR TYR B . n 
A 1 380 PRO 380 380 380 PRO PRO B . n 
A 1 381 GLY 381 381 381 GLY GLY B . n 
A 1 382 PHE 382 382 382 PHE PHE B . n 
A 1 383 ALA 383 383 383 ALA ALA B . n 
A 1 384 THR 384 384 384 THR THR B . n 
A 1 385 ASP 385 385 385 ASP ASP B . n 
A 1 386 SER 386 386 386 SER SER B . n 
A 1 387 THR 387 387 387 THR THR B . n 
A 1 388 VAL 388 388 388 VAL VAL B . n 
A 1 389 ALA 389 389 389 ALA ALA B . n 
A 1 390 LEU 390 390 390 LEU LEU B . n 
A 1 391 LEU 391 391 391 LEU LEU B . n 
A 1 392 ILE 392 392 392 ILE ILE B . n 
A 1 393 GLY 393 393 393 GLY GLY B . n 
A 1 394 LEU 394 394 394 LEU LEU B . n 
A 1 395 LEU 395 395 395 LEU LEU B . n 
A 1 396 PHE 396 396 396 PHE PHE B . n 
A 1 397 PHE 397 397 397 PHE PHE B . n 
A 1 398 LEU 398 398 398 LEU LEU B . n 
A 1 399 ILE 399 399 399 ILE ILE B . n 
A 1 400 PRO 400 400 400 PRO PRO B . n 
A 1 401 ALA 401 401 401 ALA ALA B . n 
A 1 402 LYS 402 402 402 LYS LYS B . n 
A 1 403 THR 403 403 403 THR THR B . n 
A 1 404 LEU 404 404 404 LEU LEU B . n 
A 1 405 THR 405 405 ?   ?   ?   B . n 
A 1 406 LYS 406 406 ?   ?   ?   B . n 
A 1 407 THR 407 407 ?   ?   ?   B . n 
A 1 408 THR 408 408 ?   ?   ?   B . n 
A 1 409 PRO 409 409 ?   ?   ?   B . n 
A 1 410 THR 410 410 ?   ?   ?   B . n 
A 1 411 GLY 411 411 ?   ?   ?   B . n 
A 1 412 GLU 412 412 412 GLU GLU B . n 
A 1 413 ILE 413 413 413 ILE ILE B . n 
A 1 414 VAL 414 414 414 VAL VAL B . n 
A 1 415 ALA 415 415 415 ALA ALA B . n 
A 1 416 PHE 416 416 416 PHE PHE B . n 
A 1 417 ASP 417 417 417 ASP ASP B . n 
A 1 418 TYR 418 418 418 TYR TYR B . n 
A 1 419 SER 419 419 419 SER SER B . n 
A 1 420 PRO 420 420 420 PRO PRO B . n 
A 1 421 LEU 421 421 421 LEU LEU B . n 
A 1 422 ILE 422 422 422 ILE ILE B . n 
A 1 423 THR 423 423 423 THR THR B . n 
A 1 424 TRP 424 424 424 TRP TRP B . n 
A 1 425 LYS 425 425 425 LYS LYS B . n 
A 1 426 GLU 426 426 426 GLU GLU B . n 
A 1 427 PHE 427 427 427 PHE PHE B . n 
A 1 428 GLN 428 428 428 GLN GLN B . n 
A 1 429 SER 429 429 429 SER SER B . n 
A 1 430 PHE 430 430 430 PHE PHE B . n 
A 1 431 MET 431 431 431 MET MET B . n 
A 1 432 PRO 432 432 432 PRO PRO B . n 
A 1 433 TRP 433 433 433 TRP TRP B . n 
A 1 434 ASP 434 434 434 ASP ASP B . n 
A 1 435 ILE 435 435 435 ILE ILE B . n 
A 1 436 ALA 436 436 436 ALA ALA B . n 
A 1 437 ILE 437 437 437 ILE ILE B . n 
A 1 438 LEU 438 438 438 LEU LEU B . n 
A 1 439 VAL 439 439 439 VAL VAL B . n 
A 1 440 GLY 440 440 440 GLY GLY B . n 
A 1 441 GLY 441 441 441 GLY GLY B . n 
A 1 442 GLY 442 442 442 GLY GLY B . n 
A 1 443 PHE 443 443 443 PHE PHE B . n 
A 1 444 ALA 444 444 444 ALA ALA B . n 
A 1 445 LEU 445 445 445 LEU LEU B . n 
A 1 446 ALA 446 446 446 ALA ALA B . n 
A 1 447 ASP 447 447 447 ASP ASP B . n 
A 1 448 GLY 448 448 448 GLY GLY B . n 
A 1 449 CYS 449 449 449 CYS CYS B . n 
A 1 450 GLU 450 450 450 GLU GLU B . n 
A 1 451 GLU 451 451 451 GLU GLU B . n 
A 1 452 SER 452 452 452 SER SER B . n 
A 1 453 GLY 453 453 453 GLY GLY B . n 
A 1 454 LEU 454 454 454 LEU LEU B . n 
A 1 455 SER 455 455 455 SER SER B . n 
A 1 456 LYS 456 456 456 LYS LYS B . n 
A 1 457 TRP 457 457 457 TRP TRP B . n 
A 1 458 ILE 458 458 458 ILE ILE B . n 
A 1 459 GLY 459 459 459 GLY GLY B . n 
A 1 460 ASN 460 460 460 ASN ASN B . n 
A 1 461 LYS 461 461 461 LYS LYS B . n 
A 1 462 LEU 462 462 462 LEU LEU B . n 
A 1 463 SER 463 463 463 SER SER B . n 
A 1 464 PRO 464 464 464 PRO PRO B . n 
A 1 465 LEU 465 465 465 LEU LEU B . n 
A 1 466 GLY 466 466 466 GLY GLY B . n 
A 1 467 SER 467 467 467 SER SER B . n 
A 1 468 LEU 468 468 468 LEU LEU B . n 
A 1 469 PRO 469 469 469 PRO PRO B . n 
A 1 470 ALA 470 470 470 ALA ALA B . n 
A 1 471 TRP 471 471 471 TRP TRP B . n 
A 1 472 LEU 472 472 472 LEU LEU B . n 
A 1 473 ILE 473 473 473 ILE ILE B . n 
A 1 474 ILE 474 474 474 ILE ILE B . n 
A 1 475 LEU 475 475 475 LEU LEU B . n 
A 1 476 ILE 476 476 476 ILE ILE B . n 
A 1 477 SER 477 477 477 SER SER B . n 
A 1 478 SER 478 478 478 SER SER B . n 
A 1 479 LEU 479 479 479 LEU LEU B . n 
A 1 480 MET 480 480 480 MET MET B . n 
A 1 481 VAL 481 481 481 VAL VAL B . n 
A 1 482 THR 482 482 482 THR THR B . n 
A 1 483 SER 483 483 483 SER SER B . n 
A 1 484 LEU 484 484 484 LEU LEU B . n 
A 1 485 THR 485 485 485 THR THR B . n 
A 1 486 GLU 486 486 486 GLU GLU B . n 
A 1 487 VAL 487 487 487 VAL VAL B . n 
A 1 488 ALA 488 488 488 ALA ALA B . n 
A 1 489 SER 489 489 489 SER SER B . n 
A 1 490 ASN 490 490 490 ASN ASN B . n 
A 1 491 PRO 491 491 491 PRO PRO B . n 
A 1 492 ALA 492 492 492 ALA ALA B . n 
A 1 493 THR 493 493 493 THR THR B . n 
A 1 494 ILE 494 494 494 ILE ILE B . n 
A 1 495 THR 495 495 495 THR THR B . n 
A 1 496 LEU 496 496 496 LEU LEU B . n 
A 1 497 PHE 497 497 497 PHE PHE B . n 
A 1 498 LEU 498 498 498 LEU LEU B . n 
A 1 499 PRO 499 499 499 PRO PRO B . n 
A 1 500 ILE 500 500 500 ILE ILE B . n 
A 1 501 LEU 501 501 501 LEU LEU B . n 
A 1 502 SER 502 502 502 SER SER B . n 
A 1 503 PRO 503 503 503 PRO PRO B . n 
A 1 504 LEU 504 504 504 LEU LEU B . n 
A 1 505 ALA 505 505 505 ALA ALA B . n 
A 1 506 GLU 506 506 506 GLU GLU B . n 
A 1 507 ALA 507 507 507 ALA ALA B . n 
A 1 508 ILE 508 508 508 ILE ILE B . n 
A 1 509 HIS 509 509 509 HIS HIS B . n 
A 1 510 VAL 510 510 510 VAL VAL B . n 
A 1 511 ASN 511 511 511 ASN ASN B . n 
A 1 512 PRO 512 512 512 PRO PRO B . n 
A 1 513 LEU 513 513 513 LEU LEU B . n 
A 1 514 TYR 514 514 514 TYR TYR B . n 
A 1 515 ILE 515 515 515 ILE ILE B . n 
A 1 516 LEU 516 516 516 LEU LEU B . n 
A 1 517 ILE 517 517 517 ILE ILE B . n 
A 1 518 PRO 518 518 518 PRO PRO B . n 
A 1 519 SER 519 519 519 SER SER B . n 
A 1 520 THR 520 520 520 THR THR B . n 
A 1 521 LEU 521 521 521 LEU LEU B . n 
A 1 522 CYS 522 522 522 CYS CYS B . n 
A 1 523 THR 523 523 523 THR THR B . n 
A 1 524 SER 524 524 524 SER SER B . n 
A 1 525 PHE 525 525 525 PHE PHE B . n 
A 1 526 ALA 526 526 526 ALA ALA B . n 
A 1 527 PHE 527 527 527 PHE PHE B . n 
A 1 528 LEU 528 528 528 LEU LEU B . n 
A 1 529 LEU 529 529 529 LEU LEU B . n 
A 1 530 PRO 530 530 530 PRO PRO B . n 
A 1 531 VAL 531 531 531 VAL VAL B . n 
A 1 532 ALA 532 532 532 ALA ALA B . n 
A 1 533 ASN 533 533 533 ASN ASN B . n 
A 1 534 PRO 534 534 534 PRO PRO B . n 
A 1 535 PRO 535 535 535 PRO PRO B . n 
A 1 536 ASN 536 536 536 ASN ASN B . n 
A 1 537 ALA 537 537 537 ALA ALA B . n 
A 1 538 ILE 538 538 538 ILE ILE B . n 
A 1 539 VAL 539 539 539 VAL VAL B . n 
A 1 540 PHE 540 540 540 PHE PHE B . n 
A 1 541 SER 541 541 541 SER SER B . n 
A 1 542 TYR 542 542 542 TYR TYR B . n 
A 1 543 GLY 543 543 543 GLY GLY B . n 
A 1 544 HIS 544 544 544 HIS HIS B . n 
A 1 545 LEU 545 545 545 LEU LEU B . n 
A 1 546 LYS 546 546 546 LYS LYS B . n 
A 1 547 VAL 547 547 547 VAL VAL B . n 
A 1 548 ILE 548 548 548 ILE ILE B . n 
A 1 549 ASP 549 549 549 ASP ASP B . n 
A 1 550 MET 550 550 550 MET MET B . n 
A 1 551 VAL 551 551 551 VAL VAL B . n 
A 1 552 LYS 552 552 552 LYS LYS B . n 
A 1 553 ALA 553 553 553 ALA ALA B . n 
A 1 554 GLY 554 554 554 GLY GLY B . n 
A 1 555 LEU 555 555 555 LEU LEU B . n 
A 1 556 GLY 556 556 556 GLY GLY B . n 
A 1 557 VAL 557 557 557 VAL VAL B . n 
A 1 558 ASN 558 558 558 ASN ASN B . n 
A 1 559 ILE 559 559 559 ILE ILE B . n 
A 1 560 VAL 560 560 560 VAL VAL B . n 
A 1 561 GLY 561 561 561 GLY GLY B . n 
A 1 562 VAL 562 562 562 VAL VAL B . n 
A 1 563 ALA 563 563 563 ALA ALA B . n 
A 1 564 VAL 564 564 564 VAL VAL B . n 
A 1 565 VAL 565 565 565 VAL VAL B . n 
A 1 566 MET 566 566 566 MET MET B . n 
A 1 567 LEU 567 567 567 LEU LEU B . n 
A 1 568 GLY 568 568 568 GLY GLY B . n 
A 1 569 ILE 569 569 569 ILE ILE B . n 
A 1 570 CYS 570 570 570 CYS CYS B . n 
A 1 571 THR 571 571 571 THR THR B . n 
A 1 572 TRP 572 572 572 TRP TRP B . n 
A 1 573 ILE 573 573 573 ILE ILE B . n 
A 1 574 VAL 574 574 574 VAL VAL B . n 
A 1 575 PRO 575 575 575 PRO PRO B . n 
A 1 576 MET 576 576 576 MET MET B . n 
A 1 577 PHE 577 577 577 PHE PHE B . n 
A 1 578 ASP 578 578 578 ASP ASP B . n 
A 1 579 LEU 579 579 579 LEU LEU B . n 
A 1 580 TYR 580 580 580 TYR TYR B . n 
A 1 581 THR 581 581 581 THR THR B . n 
A 1 582 TYR 582 582 582 TYR TYR B . n 
A 1 583 PRO 583 583 583 PRO PRO B . n 
A 1 584 SER 584 584 584 SER SER B . n 
A 1 585 TRP 585 585 585 TRP TRP B . n 
A 1 586 ALA 586 586 586 ALA ALA B . n 
A 1 587 PRO 587 587 587 PRO PRO B . n 
A 1 588 ALA 588 588 588 ALA ALA B . n 
A 1 589 MET 589 589 ?   ?   ?   B . n 
A 1 590 SER 590 590 ?   ?   ?   B . n 
A 1 591 ASN 591 591 ?   ?   ?   B . n 
A 1 592 GLU 592 592 ?   ?   ?   B . n 
A 1 593 THR 593 593 ?   ?   ?   B . n 
A 1 594 MET 594 594 ?   ?   ?   B . n 
A 1 595 PRO 595 595 ?   ?   ?   B . n 
B 1 1   MET 1   1   ?   ?   ?   A . n 
B 1 2   LYS 2   2   2   LYS LYS A . n 
B 1 3   PHE 3   3   3   PHE PHE A . n 
B 1 4   PHE 4   4   4   PHE PHE A . n 
B 1 5   SER 5   5   5   SER SER A . n 
B 1 6   TYR 6   6   6   TYR TYR A . n 
B 1 7   ILE 7   7   7   ILE ILE A . n 
B 1 8   LEU 8   8   8   LEU LEU A . n 
B 1 9   VAL 9   9   9   VAL VAL A . n 
B 1 10  TYR 10  10  10  TYR TYR A . n 
B 1 11  ARG 11  11  11  ARG ARG A . n 
B 1 12  ARG 12  12  12  ARG ARG A . n 
B 1 13  PHE 13  13  13  PHE PHE A . n 
B 1 14  LEU 14  14  14  LEU LEU A . n 
B 1 15  PHE 15  15  15  PHE PHE A . n 
B 1 16  VAL 16  16  16  VAL VAL A . n 
B 1 17  VAL 17  17  17  VAL VAL A . n 
B 1 18  PHE 18  18  18  PHE PHE A . n 
B 1 19  THR 19  19  19  THR THR A . n 
B 1 20  VAL 20  20  20  VAL VAL A . n 
B 1 21  LEU 21  21  21  LEU LEU A . n 
B 1 22  VAL 22  22  22  VAL VAL A . n 
B 1 23  LEU 23  23  23  LEU LEU A . n 
B 1 24  LEU 24  24  24  LEU LEU A . n 
B 1 25  PRO 25  25  25  PRO PRO A . n 
B 1 26  LEU 26  26  26  LEU LEU A . n 
B 1 27  PRO 27  27  27  PRO PRO A . n 
B 1 28  ILE 28  28  28  ILE ILE A . n 
B 1 29  VAL 29  29  29  VAL VAL A . n 
B 1 30  LEU 30  30  30  LEU LEU A . n 
B 1 31  HIS 31  31  31  HIS HIS A . n 
B 1 32  THR 32  32  32  THR THR A . n 
B 1 33  LYS 33  33  33  LYS LYS A . n 
B 1 34  GLU 34  34  34  GLU GLU A . n 
B 1 35  ALA 35  35  35  ALA ALA A . n 
B 1 36  GLU 36  36  36  GLU GLU A . n 
B 1 37  CYS 37  37  37  CYS CYS A . n 
B 1 38  ALA 38  38  38  ALA ALA A . n 
B 1 39  TYR 39  39  39  TYR TYR A . n 
B 1 40  THR 40  40  40  THR THR A . n 
B 1 41  LEU 41  41  41  LEU LEU A . n 
B 1 42  PHE 42  42  42  PHE PHE A . n 
B 1 43  VAL 43  43  43  VAL VAL A . n 
B 1 44  VAL 44  44  44  VAL VAL A . n 
B 1 45  ALA 45  45  45  ALA ALA A . n 
B 1 46  THR 46  46  46  THR THR A . n 
B 1 47  PHE 47  47  47  PHE PHE A . n 
B 1 48  TRP 48  48  48  TRP TRP A . n 
B 1 49  LEU 49  49  49  LEU LEU A . n 
B 1 50  THR 50  50  50  THR THR A . n 
B 1 51  GLU 51  51  51  GLU GLU A . n 
B 1 52  ALA 52  52  52  ALA ALA A . n 
B 1 53  LEU 53  53  53  LEU LEU A . n 
B 1 54  PRO 54  54  54  PRO PRO A . n 
B 1 55  LEU 55  55  55  LEU LEU A . n 
B 1 56  SER 56  56  56  SER SER A . n 
B 1 57  VAL 57  57  57  VAL VAL A . n 
B 1 58  THR 58  58  58  THR THR A . n 
B 1 59  ALA 59  59  59  ALA ALA A . n 
B 1 60  LEU 60  60  60  LEU LEU A . n 
B 1 61  LEU 61  61  61  LEU LEU A . n 
B 1 62  PRO 62  62  62  PRO PRO A . n 
B 1 63  SER 63  63  63  SER SER A . n 
B 1 64  LEU 64  64  64  LEU LEU A . n 
B 1 65  MET 65  65  65  MET MET A . n 
B 1 66  LEU 66  66  66  LEU LEU A . n 
B 1 67  PRO 67  67  67  PRO PRO A . n 
B 1 68  MET 68  68  68  MET MET A . n 
B 1 69  PHE 69  69  69  PHE PHE A . n 
B 1 70  GLY 70  70  70  GLY GLY A . n 
B 1 71  ILE 71  71  71  ILE ILE A . n 
B 1 72  MET 72  72  72  MET MET A . n 
B 1 73  PRO 73  73  73  PRO PRO A . n 
B 1 74  SER 74  74  74  SER SER A . n 
B 1 75  LYS 75  75  75  LYS LYS A . n 
B 1 76  LYS 76  76  76  LYS LYS A . n 
B 1 77  VAL 77  77  77  VAL VAL A . n 
B 1 78  ALA 78  78  78  ALA ALA A . n 
B 1 79  SER 79  79  79  SER SER A . n 
B 1 80  ALA 80  80  80  ALA ALA A . n 
B 1 81  TYR 81  81  81  TYR TYR A . n 
B 1 82  PHE 82  82  82  PHE PHE A . n 
B 1 83  LYS 83  83  83  LYS LYS A . n 
B 1 84  ASP 84  84  84  ASP ASP A . n 
B 1 85  PHE 85  85  85  PHE PHE A . n 
B 1 86  HIS 86  86  86  HIS HIS A . n 
B 1 87  LEU 87  87  87  LEU LEU A . n 
B 1 88  LEU 88  88  88  LEU LEU A . n 
B 1 89  LEU 89  89  89  LEU LEU A . n 
B 1 90  ILE 90  90  90  ILE ILE A . n 
B 1 91  GLY 91  91  91  GLY GLY A . n 
B 1 92  VAL 92  92  92  VAL VAL A . n 
B 1 93  ILE 93  93  93  ILE ILE A . n 
B 1 94  CYS 94  94  94  CYS CYS A . n 
B 1 95  LEU 95  95  95  LEU LEU A . n 
B 1 96  ALA 96  96  96  ALA ALA A . n 
B 1 97  THR 97  97  97  THR THR A . n 
B 1 98  SER 98  98  98  SER SER A . n 
B 1 99  ILE 99  99  99  ILE ILE A . n 
B 1 100 GLU 100 100 100 GLU GLU A . n 
B 1 101 LYS 101 101 101 LYS LYS A . n 
B 1 102 TRP 102 102 102 TRP TRP A . n 
B 1 103 ASN 103 103 103 ASN ASN A . n 
B 1 104 LEU 104 104 104 LEU LEU A . n 
B 1 105 HIS 105 105 105 HIS HIS A . n 
B 1 106 LYS 106 106 106 LYS LYS A . n 
B 1 107 ARG 107 107 107 ARG ARG A . n 
B 1 108 ILE 108 108 108 ILE ILE A . n 
B 1 109 ALA 109 109 109 ALA ALA A . n 
B 1 110 LEU 110 110 110 LEU LEU A . n 
B 1 111 LYS 111 111 111 LYS LYS A . n 
B 1 112 MET 112 112 112 MET MET A . n 
B 1 113 VAL 113 113 113 VAL VAL A . n 
B 1 114 MET 114 114 114 MET MET A . n 
B 1 115 MET 115 115 115 MET MET A . n 
B 1 116 VAL 116 116 116 VAL VAL A . n 
B 1 117 GLY 117 117 117 GLY GLY A . n 
B 1 118 VAL 118 118 118 VAL VAL A . n 
B 1 119 ASN 119 119 119 ASN ASN A . n 
B 1 120 PRO 120 120 120 PRO PRO A . n 
B 1 121 ALA 121 121 121 ALA ALA A . n 
B 1 122 TRP 122 122 122 TRP TRP A . n 
B 1 123 LEU 123 123 123 LEU LEU A . n 
B 1 124 THR 124 124 124 THR THR A . n 
B 1 125 LEU 125 125 125 LEU LEU A . n 
B 1 126 GLY 126 126 126 GLY GLY A . n 
B 1 127 PHE 127 127 127 PHE PHE A . n 
B 1 128 MET 128 128 128 MET MET A . n 
B 1 129 SER 129 129 129 SER SER A . n 
B 1 130 SER 130 130 130 SER SER A . n 
B 1 131 THR 131 131 131 THR THR A . n 
B 1 132 ALA 132 132 132 ALA ALA A . n 
B 1 133 PHE 133 133 133 PHE PHE A . n 
B 1 134 LEU 134 134 134 LEU LEU A . n 
B 1 135 SER 135 135 135 SER SER A . n 
B 1 136 MET 136 136 136 MET MET A . n 
B 1 137 TRP 137 137 137 TRP TRP A . n 
B 1 138 LEU 138 138 138 LEU LEU A . n 
B 1 139 SER 139 139 139 SER SER A . n 
B 1 140 ASN 140 140 140 ASN ASN A . n 
B 1 141 THR 141 141 141 THR THR A . n 
B 1 142 SER 142 142 142 SER SER A . n 
B 1 143 THR 143 143 143 THR THR A . n 
B 1 144 ALA 144 144 144 ALA ALA A . n 
B 1 145 ALA 145 145 145 ALA ALA A . n 
B 1 146 MET 146 146 146 MET MET A . n 
B 1 147 VAL 147 147 147 VAL VAL A . n 
B 1 148 MET 148 148 148 MET MET A . n 
B 1 149 PRO 149 149 149 PRO PRO A . n 
B 1 150 ILE 150 150 150 ILE ILE A . n 
B 1 151 ALA 151 151 151 ALA ALA A . n 
B 1 152 GLU 152 152 152 GLU GLU A . n 
B 1 153 ALA 153 153 153 ALA ALA A . n 
B 1 154 VAL 154 154 154 VAL VAL A . n 
B 1 155 VAL 155 155 155 VAL VAL A . n 
B 1 156 GLN 156 156 156 GLN GLN A . n 
B 1 157 GLN 157 157 157 GLN GLN A . n 
B 1 158 ILE 158 158 158 ILE ILE A . n 
B 1 159 ILE 159 159 159 ILE ILE A . n 
B 1 160 ASN 160 160 160 ASN ASN A . n 
B 1 161 ALA 161 161 161 ALA ALA A . n 
B 1 162 GLU 162 162 ?   ?   ?   A . n 
B 1 163 ALA 163 163 ?   ?   ?   A . n 
B 1 164 GLU 164 164 ?   ?   ?   A . n 
B 1 165 VAL 165 165 ?   ?   ?   A . n 
B 1 166 GLU 166 166 ?   ?   ?   A . n 
B 1 167 ALA 167 167 ?   ?   ?   A . n 
B 1 168 THR 168 168 ?   ?   ?   A . n 
B 1 169 GLN 169 169 ?   ?   ?   A . n 
B 1 170 MET 170 170 ?   ?   ?   A . n 
B 1 171 THR 171 171 ?   ?   ?   A . n 
B 1 172 TYR 172 172 ?   ?   ?   A . n 
B 1 173 PHE 173 173 ?   ?   ?   A . n 
B 1 174 ASN 174 174 ?   ?   ?   A . n 
B 1 175 GLY 175 175 ?   ?   ?   A . n 
B 1 176 SER 176 176 ?   ?   ?   A . n 
B 1 177 THR 177 177 ?   ?   ?   A . n 
B 1 178 ASN 178 178 ?   ?   ?   A . n 
B 1 179 HIS 179 179 ?   ?   ?   A . n 
B 1 180 GLY 180 180 ?   ?   ?   A . n 
B 1 181 LEU 181 181 ?   ?   ?   A . n 
B 1 182 GLU 182 182 ?   ?   ?   A . n 
B 1 183 ILE 183 183 ?   ?   ?   A . n 
B 1 184 ASP 184 184 ?   ?   ?   A . n 
B 1 185 GLU 185 185 ?   ?   ?   A . n 
B 1 186 SER 186 186 ?   ?   ?   A . n 
B 1 187 VAL 187 187 ?   ?   ?   A . n 
B 1 188 ASN 188 188 ?   ?   ?   A . n 
B 1 189 GLY 189 189 ?   ?   ?   A . n 
B 1 190 HIS 190 190 ?   ?   ?   A . n 
B 1 191 GLU 191 191 ?   ?   ?   A . n 
B 1 192 ILE 192 192 ?   ?   ?   A . n 
B 1 193 ASN 193 193 ?   ?   ?   A . n 
B 1 194 GLU 194 194 ?   ?   ?   A . n 
B 1 195 ARG 195 195 ?   ?   ?   A . n 
B 1 196 LYS 196 196 ?   ?   ?   A . n 
B 1 197 GLU 197 197 ?   ?   ?   A . n 
B 1 198 LYS 198 198 ?   ?   ?   A . n 
B 1 199 THR 199 199 ?   ?   ?   A . n 
B 1 200 LYS 200 200 ?   ?   ?   A . n 
B 1 201 PRO 201 201 ?   ?   ?   A . n 
B 1 202 VAL 202 202 ?   ?   ?   A . n 
B 1 203 PRO 203 203 ?   ?   ?   A . n 
B 1 204 GLY 204 204 ?   ?   ?   A . n 
B 1 205 TYR 205 205 ?   ?   ?   A . n 
B 1 206 ASN 206 206 ?   ?   ?   A . n 
B 1 207 ASN 207 207 ?   ?   ?   A . n 
B 1 208 ASP 208 208 ?   ?   ?   A . n 
B 1 209 THR 209 209 ?   ?   ?   A . n 
B 1 210 GLY 210 210 ?   ?   ?   A . n 
B 1 211 LYS 211 211 ?   ?   ?   A . n 
B 1 212 ILE 212 212 ?   ?   ?   A . n 
B 1 213 SER 213 213 ?   ?   ?   A . n 
B 1 214 SER 214 214 ?   ?   ?   A . n 
B 1 215 LYS 215 215 ?   ?   ?   A . n 
B 1 216 VAL 216 216 ?   ?   ?   A . n 
B 1 217 GLU 217 217 ?   ?   ?   A . n 
B 1 218 LEU 218 218 ?   ?   ?   A . n 
B 1 219 GLU 219 219 ?   ?   ?   A . n 
B 1 220 LYS 220 220 ?   ?   ?   A . n 
B 1 221 ASN 221 221 ?   ?   ?   A . n 
B 1 222 SER 222 222 ?   ?   ?   A . n 
B 1 223 GLY 223 223 ?   ?   ?   A . n 
B 1 224 MET 224 224 ?   ?   ?   A . n 
B 1 225 ARG 225 225 ?   ?   ?   A . n 
B 1 226 THR 226 226 ?   ?   ?   A . n 
B 1 227 LYS 227 227 ?   ?   ?   A . n 
B 1 228 TYR 228 228 ?   ?   ?   A . n 
B 1 229 ARG 229 229 ?   ?   ?   A . n 
B 1 230 THR 230 230 230 THR THR A . n 
B 1 231 LYS 231 231 231 LYS LYS A . n 
B 1 232 LYS 232 232 232 LYS LYS A . n 
B 1 233 GLY 233 233 233 GLY GLY A . n 
B 1 234 HIS 234 234 234 HIS HIS A . n 
B 1 235 VAL 235 235 235 VAL VAL A . n 
B 1 236 THR 236 236 236 THR THR A . n 
B 1 237 ARG 237 237 237 ARG ARG A . n 
B 1 238 LYS 238 238 238 LYS LYS A . n 
B 1 239 LEU 239 239 239 LEU LEU A . n 
B 1 240 THR 240 240 240 THR THR A . n 
B 1 241 CYS 241 241 241 CYS CYS A . n 
B 1 242 LEU 242 242 242 LEU LEU A . n 
B 1 243 CYS 243 243 243 CYS CYS A . n 
B 1 244 ILE 244 244 244 ILE ILE A . n 
B 1 245 ALA 245 245 245 ALA ALA A . n 
B 1 246 TYR 246 246 246 TYR TYR A . n 
B 1 247 SER 247 247 247 SER SER A . n 
B 1 248 SER 248 248 248 SER SER A . n 
B 1 249 THR 249 249 249 THR THR A . n 
B 1 250 ILE 250 250 250 ILE ILE A . n 
B 1 251 GLY 251 251 251 GLY GLY A . n 
B 1 252 GLY 252 252 252 GLY GLY A . n 
B 1 253 LEU 253 253 253 LEU LEU A . n 
B 1 254 THR 254 254 254 THR THR A . n 
B 1 255 THR 255 255 255 THR THR A . n 
B 1 256 ILE 256 256 256 ILE ILE A . n 
B 1 257 THR 257 257 257 THR THR A . n 
B 1 258 GLY 258 258 258 GLY GLY A . n 
B 1 259 THR 259 259 259 THR THR A . n 
B 1 260 SER 260 260 260 SER SER A . n 
B 1 261 THR 261 261 261 THR THR A . n 
B 1 262 ASN 262 262 262 ASN ASN A . n 
B 1 263 LEU 263 263 263 LEU LEU A . n 
B 1 264 ILE 264 264 264 ILE ILE A . n 
B 1 265 PHE 265 265 265 PHE PHE A . n 
B 1 266 ALA 266 266 266 ALA ALA A . n 
B 1 267 GLU 267 267 267 GLU GLU A . n 
B 1 268 TYR 268 268 268 TYR TYR A . n 
B 1 269 PHE 269 269 269 PHE PHE A . n 
B 1 270 ASN 270 270 270 ASN ASN A . n 
B 1 271 THR 271 271 271 THR THR A . n 
B 1 272 ARG 272 272 272 ARG ARG A . n 
B 1 273 TYR 273 273 273 TYR TYR A . n 
B 1 274 PRO 274 274 274 PRO PRO A . n 
B 1 275 ASP 275 275 275 ASP ASP A . n 
B 1 276 CYS 276 276 276 CYS CYS A . n 
B 1 277 ARG 277 277 277 ARG ARG A . n 
B 1 278 CYS 278 278 278 CYS CYS A . n 
B 1 279 LEU 279 279 279 LEU LEU A . n 
B 1 280 ASN 280 280 280 ASN ASN A . n 
B 1 281 PHE 281 281 281 PHE PHE A . n 
B 1 282 GLY 282 282 282 GLY GLY A . n 
B 1 283 SER 283 283 283 SER SER A . n 
B 1 284 TRP 284 284 284 TRP TRP A . n 
B 1 285 PHE 285 285 285 PHE PHE A . n 
B 1 286 THR 286 286 286 THR THR A . n 
B 1 287 PHE 287 287 287 PHE PHE A . n 
B 1 288 SER 288 288 288 SER SER A . n 
B 1 289 PHE 289 289 289 PHE PHE A . n 
B 1 290 PRO 290 290 290 PRO PRO A . n 
B 1 291 ALA 291 291 291 ALA ALA A . n 
B 1 292 ALA 292 292 292 ALA ALA A . n 
B 1 293 LEU 293 293 293 LEU LEU A . n 
B 1 294 ILE 294 294 294 ILE ILE A . n 
B 1 295 ILE 295 295 295 ILE ILE A . n 
B 1 296 LEU 296 296 296 LEU LEU A . n 
B 1 297 LEU 297 297 297 LEU LEU A . n 
B 1 298 LEU 298 298 298 LEU LEU A . n 
B 1 299 SER 299 299 299 SER SER A . n 
B 1 300 TRP 300 300 300 TRP TRP A . n 
B 1 301 ILE 301 301 301 ILE ILE A . n 
B 1 302 TRP 302 302 302 TRP TRP A . n 
B 1 303 LEU 303 303 303 LEU LEU A . n 
B 1 304 GLN 304 304 304 GLN GLN A . n 
B 1 305 TRP 305 305 305 TRP TRP A . n 
B 1 306 LEU 306 306 306 LEU LEU A . n 
B 1 307 PHE 307 307 307 PHE PHE A . n 
B 1 308 LEU 308 308 308 LEU LEU A . n 
B 1 309 GLY 309 309 309 GLY GLY A . n 
B 1 310 PHE 310 310 310 PHE PHE A . n 
B 1 311 ASN 311 311 311 ASN ASN A . n 
B 1 312 PHE 312 312 312 PHE PHE A . n 
B 1 313 LYS 313 313 313 LYS LYS A . n 
B 1 314 GLU 314 314 314 GLU GLU A . n 
B 1 315 MET 315 315 315 MET MET A . n 
B 1 316 PHE 316 316 316 PHE PHE A . n 
B 1 317 LYS 317 317 ?   ?   ?   A . n 
B 1 318 CYS 318 318 ?   ?   ?   A . n 
B 1 319 GLY 319 319 ?   ?   ?   A . n 
B 1 320 LYS 320 320 ?   ?   ?   A . n 
B 1 321 THR 321 321 321 THR THR A . n 
B 1 322 LYS 322 322 322 LYS LYS A . n 
B 1 323 THR 323 323 323 THR THR A . n 
B 1 324 VAL 324 324 324 VAL VAL A . n 
B 1 325 GLN 325 325 325 GLN GLN A . n 
B 1 326 GLN 326 326 326 GLN GLN A . n 
B 1 327 LYS 327 327 327 LYS LYS A . n 
B 1 328 ALA 328 328 328 ALA ALA A . n 
B 1 329 CYS 329 329 329 CYS CYS A . n 
B 1 330 ALA 330 330 330 ALA ALA A . n 
B 1 331 GLU 331 331 331 GLU GLU A . n 
B 1 332 VAL 332 332 332 VAL VAL A . n 
B 1 333 ILE 333 333 333 ILE ILE A . n 
B 1 334 LYS 334 334 334 LYS LYS A . n 
B 1 335 GLN 335 335 335 GLN GLN A . n 
B 1 336 GLU 336 336 336 GLU GLU A . n 
B 1 337 TYR 337 337 337 TYR TYR A . n 
B 1 338 GLN 338 338 338 GLN GLN A . n 
B 1 339 LYS 339 339 339 LYS LYS A . n 
B 1 340 LEU 340 340 340 LEU LEU A . n 
B 1 341 GLY 341 341 341 GLY GLY A . n 
B 1 342 PRO 342 342 342 PRO PRO A . n 
B 1 343 ILE 343 343 343 ILE ILE A . n 
B 1 344 ARG 344 344 344 ARG ARG A . n 
B 1 345 TYR 345 345 345 TYR TYR A . n 
B 1 346 GLN 346 346 346 GLN GLN A . n 
B 1 347 GLU 347 347 347 GLU GLU A . n 
B 1 348 ILE 348 348 348 ILE ILE A . n 
B 1 349 VAL 349 349 349 VAL VAL A . n 
B 1 350 THR 350 350 350 THR THR A . n 
B 1 351 LEU 351 351 351 LEU LEU A . n 
B 1 352 VAL 352 352 352 VAL VAL A . n 
B 1 353 LEU 353 353 353 LEU LEU A . n 
B 1 354 PHE 354 354 354 PHE PHE A . n 
B 1 355 ILE 355 355 355 ILE ILE A . n 
B 1 356 ILE 356 356 356 ILE ILE A . n 
B 1 357 MET 357 357 357 MET MET A . n 
B 1 358 ALA 358 358 358 ALA ALA A . n 
B 1 359 LEU 359 359 359 LEU LEU A . n 
B 1 360 LEU 360 360 360 LEU LEU A . n 
B 1 361 TRP 361 361 361 TRP TRP A . n 
B 1 362 PHE 362 362 362 PHE PHE A . n 
B 1 363 SER 363 363 363 SER SER A . n 
B 1 364 ARG 364 364 364 ARG ARG A . n 
B 1 365 ASP 365 365 365 ASP ASP A . n 
B 1 366 PRO 366 366 366 PRO PRO A . n 
B 1 367 GLY 367 367 367 GLY GLY A . n 
B 1 368 PHE 368 368 368 PHE PHE A . n 
B 1 369 VAL 369 369 369 VAL VAL A . n 
B 1 370 PRO 370 370 370 PRO PRO A . n 
B 1 371 GLY 371 371 371 GLY GLY A . n 
B 1 372 TRP 372 372 372 TRP TRP A . n 
B 1 373 SER 373 373 373 SER SER A . n 
B 1 374 ALA 374 374 374 ALA ALA A . n 
B 1 375 LEU 375 375 375 LEU LEU A . n 
B 1 376 PHE 376 376 376 PHE PHE A . n 
B 1 377 SER 377 377 377 SER SER A . n 
B 1 378 GLU 378 378 378 GLU GLU A . n 
B 1 379 TYR 379 379 379 TYR TYR A . n 
B 1 380 PRO 380 380 380 PRO PRO A . n 
B 1 381 GLY 381 381 381 GLY GLY A . n 
B 1 382 PHE 382 382 382 PHE PHE A . n 
B 1 383 ALA 383 383 383 ALA ALA A . n 
B 1 384 THR 384 384 384 THR THR A . n 
B 1 385 ASP 385 385 385 ASP ASP A . n 
B 1 386 SER 386 386 386 SER SER A . n 
B 1 387 THR 387 387 387 THR THR A . n 
B 1 388 VAL 388 388 388 VAL VAL A . n 
B 1 389 ALA 389 389 389 ALA ALA A . n 
B 1 390 LEU 390 390 390 LEU LEU A . n 
B 1 391 LEU 391 391 391 LEU LEU A . n 
B 1 392 ILE 392 392 392 ILE ILE A . n 
B 1 393 GLY 393 393 393 GLY GLY A . n 
B 1 394 LEU 394 394 394 LEU LEU A . n 
B 1 395 LEU 395 395 395 LEU LEU A . n 
B 1 396 PHE 396 396 396 PHE PHE A . n 
B 1 397 PHE 397 397 397 PHE PHE A . n 
B 1 398 LEU 398 398 398 LEU LEU A . n 
B 1 399 ILE 399 399 399 ILE ILE A . n 
B 1 400 PRO 400 400 400 PRO PRO A . n 
B 1 401 ALA 401 401 401 ALA ALA A . n 
B 1 402 LYS 402 402 402 LYS LYS A . n 
B 1 403 THR 403 403 403 THR THR A . n 
B 1 404 LEU 404 404 404 LEU LEU A . n 
B 1 405 THR 405 405 ?   ?   ?   A . n 
B 1 406 LYS 406 406 ?   ?   ?   A . n 
B 1 407 THR 407 407 ?   ?   ?   A . n 
B 1 408 THR 408 408 ?   ?   ?   A . n 
B 1 409 PRO 409 409 ?   ?   ?   A . n 
B 1 410 THR 410 410 ?   ?   ?   A . n 
B 1 411 GLY 411 411 ?   ?   ?   A . n 
B 1 412 GLU 412 412 412 GLU GLU A . n 
B 1 413 ILE 413 413 413 ILE ILE A . n 
B 1 414 VAL 414 414 414 VAL VAL A . n 
B 1 415 ALA 415 415 415 ALA ALA A . n 
B 1 416 PHE 416 416 416 PHE PHE A . n 
B 1 417 ASP 417 417 417 ASP ASP A . n 
B 1 418 TYR 418 418 418 TYR TYR A . n 
B 1 419 SER 419 419 419 SER SER A . n 
B 1 420 PRO 420 420 420 PRO PRO A . n 
B 1 421 LEU 421 421 421 LEU LEU A . n 
B 1 422 ILE 422 422 422 ILE ILE A . n 
B 1 423 THR 423 423 423 THR THR A . n 
B 1 424 TRP 424 424 424 TRP TRP A . n 
B 1 425 LYS 425 425 425 LYS LYS A . n 
B 1 426 GLU 426 426 426 GLU GLU A . n 
B 1 427 PHE 427 427 427 PHE PHE A . n 
B 1 428 GLN 428 428 428 GLN GLN A . n 
B 1 429 SER 429 429 429 SER SER A . n 
B 1 430 PHE 430 430 430 PHE PHE A . n 
B 1 431 MET 431 431 431 MET MET A . n 
B 1 432 PRO 432 432 432 PRO PRO A . n 
B 1 433 TRP 433 433 433 TRP TRP A . n 
B 1 434 ASP 434 434 434 ASP ASP A . n 
B 1 435 ILE 435 435 435 ILE ILE A . n 
B 1 436 ALA 436 436 436 ALA ALA A . n 
B 1 437 ILE 437 437 437 ILE ILE A . n 
B 1 438 LEU 438 438 438 LEU LEU A . n 
B 1 439 VAL 439 439 439 VAL VAL A . n 
B 1 440 GLY 440 440 440 GLY GLY A . n 
B 1 441 GLY 441 441 441 GLY GLY A . n 
B 1 442 GLY 442 442 442 GLY GLY A . n 
B 1 443 PHE 443 443 443 PHE PHE A . n 
B 1 444 ALA 444 444 444 ALA ALA A . n 
B 1 445 LEU 445 445 445 LEU LEU A . n 
B 1 446 ALA 446 446 446 ALA ALA A . n 
B 1 447 ASP 447 447 447 ASP ASP A . n 
B 1 448 GLY 448 448 448 GLY GLY A . n 
B 1 449 CYS 449 449 449 CYS CYS A . n 
B 1 450 GLU 450 450 450 GLU GLU A . n 
B 1 451 GLU 451 451 451 GLU GLU A . n 
B 1 452 SER 452 452 452 SER SER A . n 
B 1 453 GLY 453 453 453 GLY GLY A . n 
B 1 454 LEU 454 454 454 LEU LEU A . n 
B 1 455 SER 455 455 455 SER SER A . n 
B 1 456 LYS 456 456 456 LYS LYS A . n 
B 1 457 TRP 457 457 457 TRP TRP A . n 
B 1 458 ILE 458 458 458 ILE ILE A . n 
B 1 459 GLY 459 459 459 GLY GLY A . n 
B 1 460 ASN 460 460 460 ASN ASN A . n 
B 1 461 LYS 461 461 461 LYS LYS A . n 
B 1 462 LEU 462 462 462 LEU LEU A . n 
B 1 463 SER 463 463 463 SER SER A . n 
B 1 464 PRO 464 464 464 PRO PRO A . n 
B 1 465 LEU 465 465 465 LEU LEU A . n 
B 1 466 GLY 466 466 466 GLY GLY A . n 
B 1 467 SER 467 467 467 SER SER A . n 
B 1 468 LEU 468 468 468 LEU LEU A . n 
B 1 469 PRO 469 469 469 PRO PRO A . n 
B 1 470 ALA 470 470 470 ALA ALA A . n 
B 1 471 TRP 471 471 471 TRP TRP A . n 
B 1 472 LEU 472 472 472 LEU LEU A . n 
B 1 473 ILE 473 473 473 ILE ILE A . n 
B 1 474 ILE 474 474 474 ILE ILE A . n 
B 1 475 LEU 475 475 475 LEU LEU A . n 
B 1 476 ILE 476 476 476 ILE ILE A . n 
B 1 477 SER 477 477 477 SER SER A . n 
B 1 478 SER 478 478 478 SER SER A . n 
B 1 479 LEU 479 479 479 LEU LEU A . n 
B 1 480 MET 480 480 480 MET MET A . n 
B 1 481 VAL 481 481 481 VAL VAL A . n 
B 1 482 THR 482 482 482 THR THR A . n 
B 1 483 SER 483 483 483 SER SER A . n 
B 1 484 LEU 484 484 484 LEU LEU A . n 
B 1 485 THR 485 485 485 THR THR A . n 
B 1 486 GLU 486 486 486 GLU GLU A . n 
B 1 487 VAL 487 487 487 VAL VAL A . n 
B 1 488 ALA 488 488 488 ALA ALA A . n 
B 1 489 SER 489 489 489 SER SER A . n 
B 1 490 ASN 490 490 490 ASN ASN A . n 
B 1 491 PRO 491 491 491 PRO PRO A . n 
B 1 492 ALA 492 492 492 ALA ALA A . n 
B 1 493 THR 493 493 493 THR THR A . n 
B 1 494 ILE 494 494 494 ILE ILE A . n 
B 1 495 THR 495 495 495 THR THR A . n 
B 1 496 LEU 496 496 496 LEU LEU A . n 
B 1 497 PHE 497 497 497 PHE PHE A . n 
B 1 498 LEU 498 498 498 LEU LEU A . n 
B 1 499 PRO 499 499 499 PRO PRO A . n 
B 1 500 ILE 500 500 500 ILE ILE A . n 
B 1 501 LEU 501 501 501 LEU LEU A . n 
B 1 502 SER 502 502 502 SER SER A . n 
B 1 503 PRO 503 503 503 PRO PRO A . n 
B 1 504 LEU 504 504 504 LEU LEU A . n 
B 1 505 ALA 505 505 505 ALA ALA A . n 
B 1 506 GLU 506 506 506 GLU GLU A . n 
B 1 507 ALA 507 507 507 ALA ALA A . n 
B 1 508 ILE 508 508 508 ILE ILE A . n 
B 1 509 HIS 509 509 509 HIS HIS A . n 
B 1 510 VAL 510 510 510 VAL VAL A . n 
B 1 511 ASN 511 511 511 ASN ASN A . n 
B 1 512 PRO 512 512 512 PRO PRO A . n 
B 1 513 LEU 513 513 513 LEU LEU A . n 
B 1 514 TYR 514 514 514 TYR TYR A . n 
B 1 515 ILE 515 515 515 ILE ILE A . n 
B 1 516 LEU 516 516 516 LEU LEU A . n 
B 1 517 ILE 517 517 517 ILE ILE A . n 
B 1 518 PRO 518 518 518 PRO PRO A . n 
B 1 519 SER 519 519 519 SER SER A . n 
B 1 520 THR 520 520 520 THR THR A . n 
B 1 521 LEU 521 521 521 LEU LEU A . n 
B 1 522 CYS 522 522 522 CYS CYS A . n 
B 1 523 THR 523 523 523 THR THR A . n 
B 1 524 SER 524 524 524 SER SER A . n 
B 1 525 PHE 525 525 525 PHE PHE A . n 
B 1 526 ALA 526 526 526 ALA ALA A . n 
B 1 527 PHE 527 527 527 PHE PHE A . n 
B 1 528 LEU 528 528 528 LEU LEU A . n 
B 1 529 LEU 529 529 529 LEU LEU A . n 
B 1 530 PRO 530 530 530 PRO PRO A . n 
B 1 531 VAL 531 531 531 VAL VAL A . n 
B 1 532 ALA 532 532 532 ALA ALA A . n 
B 1 533 ASN 533 533 533 ASN ASN A . n 
B 1 534 PRO 534 534 534 PRO PRO A . n 
B 1 535 PRO 535 535 535 PRO PRO A . n 
B 1 536 ASN 536 536 536 ASN ASN A . n 
B 1 537 ALA 537 537 537 ALA ALA A . n 
B 1 538 ILE 538 538 538 ILE ILE A . n 
B 1 539 VAL 539 539 539 VAL VAL A . n 
B 1 540 PHE 540 540 540 PHE PHE A . n 
B 1 541 SER 541 541 541 SER SER A . n 
B 1 542 TYR 542 542 542 TYR TYR A . n 
B 1 543 GLY 543 543 543 GLY GLY A . n 
B 1 544 HIS 544 544 544 HIS HIS A . n 
B 1 545 LEU 545 545 545 LEU LEU A . n 
B 1 546 LYS 546 546 546 LYS LYS A . n 
B 1 547 VAL 547 547 547 VAL VAL A . n 
B 1 548 ILE 548 548 548 ILE ILE A . n 
B 1 549 ASP 549 549 549 ASP ASP A . n 
B 1 550 MET 550 550 550 MET MET A . n 
B 1 551 VAL 551 551 551 VAL VAL A . n 
B 1 552 LYS 552 552 552 LYS LYS A . n 
B 1 553 ALA 553 553 553 ALA ALA A . n 
B 1 554 GLY 554 554 554 GLY GLY A . n 
B 1 555 LEU 555 555 555 LEU LEU A . n 
B 1 556 GLY 556 556 556 GLY GLY A . n 
B 1 557 VAL 557 557 557 VAL VAL A . n 
B 1 558 ASN 558 558 558 ASN ASN A . n 
B 1 559 ILE 559 559 559 ILE ILE A . n 
B 1 560 VAL 560 560 560 VAL VAL A . n 
B 1 561 GLY 561 561 561 GLY GLY A . n 
B 1 562 VAL 562 562 562 VAL VAL A . n 
B 1 563 ALA 563 563 563 ALA ALA A . n 
B 1 564 VAL 564 564 564 VAL VAL A . n 
B 1 565 VAL 565 565 565 VAL VAL A . n 
B 1 566 MET 566 566 566 MET MET A . n 
B 1 567 LEU 567 567 567 LEU LEU A . n 
B 1 568 GLY 568 568 568 GLY GLY A . n 
B 1 569 ILE 569 569 569 ILE ILE A . n 
B 1 570 CYS 570 570 570 CYS CYS A . n 
B 1 571 THR 571 571 571 THR THR A . n 
B 1 572 TRP 572 572 572 TRP TRP A . n 
B 1 573 ILE 573 573 573 ILE ILE A . n 
B 1 574 VAL 574 574 574 VAL VAL A . n 
B 1 575 PRO 575 575 575 PRO PRO A . n 
B 1 576 MET 576 576 576 MET MET A . n 
B 1 577 PHE 577 577 577 PHE PHE A . n 
B 1 578 ASP 578 578 578 ASP ASP A . n 
B 1 579 LEU 579 579 579 LEU LEU A . n 
B 1 580 TYR 580 580 580 TYR TYR A . n 
B 1 581 THR 581 581 581 THR THR A . n 
B 1 582 TYR 582 582 582 TYR TYR A . n 
B 1 583 PRO 583 583 583 PRO PRO A . n 
B 1 584 SER 584 584 584 SER SER A . n 
B 1 585 TRP 585 585 585 TRP TRP A . n 
B 1 586 ALA 586 586 586 ALA ALA A . n 
B 1 587 PRO 587 587 587 PRO PRO A . n 
B 1 588 ALA 588 588 588 ALA ALA A . n 
B 1 589 MET 589 589 ?   ?   ?   A . n 
B 1 590 SER 590 590 ?   ?   ?   A . n 
B 1 591 ASN 591 591 ?   ?   ?   A . n 
B 1 592 GLU 592 592 ?   ?   ?   A . n 
B 1 593 THR 593 593 ?   ?   ?   A . n 
B 1 594 MET 594 594 ?   ?   ?   A . n 
B 1 595 PRO 595 595 ?   ?   ?   A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 SO4 1 601 899 SO4 SO4 B . 
D 3 NA  1 602 902 NA  NA  B . 
E 2 SO4 1 601 899 SO4 SO4 A . 
F 3 NA  1 602 902 NA  NA  A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 B LYS 75  ? CG  ? A LYS 75  CG  
2  1 Y 1 B LYS 75  ? CD  ? A LYS 75  CD  
3  1 Y 1 B LYS 75  ? CE  ? A LYS 75  CE  
4  1 Y 1 B LYS 75  ? NZ  ? A LYS 75  NZ  
5  1 Y 1 B CYS 276 ? SG  ? A CYS 276 SG  
6  1 Y 1 B GLU 314 ? CG  ? A GLU 314 CG  
7  1 Y 1 B GLU 314 ? CD  ? A GLU 314 CD  
8  1 Y 1 B GLU 314 ? OE1 ? A GLU 314 OE1 
9  1 Y 1 B GLU 314 ? OE2 ? A GLU 314 OE2 
10 1 Y 1 B THR 321 ? OG1 ? A THR 321 OG1 
11 1 Y 1 B THR 321 ? CG2 ? A THR 321 CG2 
12 1 Y 1 B LYS 322 ? CG  ? A LYS 322 CG  
13 1 Y 1 B LYS 322 ? CD  ? A LYS 322 CD  
14 1 Y 1 B LYS 322 ? CE  ? A LYS 322 CE  
15 1 Y 1 B LYS 322 ? NZ  ? A LYS 322 NZ  
16 1 Y 1 B PHE 368 ? CG  ? A PHE 368 CG  
17 1 Y 1 B PHE 368 ? CD1 ? A PHE 368 CD1 
18 1 Y 1 B PHE 368 ? CD2 ? A PHE 368 CD2 
19 1 Y 1 B PHE 368 ? CE1 ? A PHE 368 CE1 
20 1 Y 1 B PHE 368 ? CE2 ? A PHE 368 CE2 
21 1 Y 1 B PHE 368 ? CZ  ? A PHE 368 CZ  
22 1 Y 1 B TRP 372 ? CG  ? A TRP 372 CG  
23 1 Y 1 B TRP 372 ? CD1 ? A TRP 372 CD1 
24 1 Y 1 B TRP 372 ? CD2 ? A TRP 372 CD2 
25 1 Y 1 B TRP 372 ? NE1 ? A TRP 372 NE1 
26 1 Y 1 B TRP 372 ? CE2 ? A TRP 372 CE2 
27 1 Y 1 B TRP 372 ? CE3 ? A TRP 372 CE3 
28 1 Y 1 B TRP 372 ? CZ2 ? A TRP 372 CZ2 
29 1 Y 1 B TRP 372 ? CZ3 ? A TRP 372 CZ3 
30 1 Y 1 B TRP 372 ? CH2 ? A TRP 372 CH2 
31 1 Y 1 A LYS 75  ? CG  ? B LYS 75  CG  
32 1 Y 1 A LYS 75  ? CD  ? B LYS 75  CD  
33 1 Y 1 A LYS 75  ? CE  ? B LYS 75  CE  
34 1 Y 1 A LYS 75  ? NZ  ? B LYS 75  NZ  
35 1 Y 1 A CYS 276 ? SG  ? B CYS 276 SG  
36 1 Y 1 A GLU 314 ? CG  ? B GLU 314 CG  
37 1 Y 1 A GLU 314 ? CD  ? B GLU 314 CD  
38 1 Y 1 A GLU 314 ? OE1 ? B GLU 314 OE1 
39 1 Y 1 A GLU 314 ? OE2 ? B GLU 314 OE2 
40 1 Y 1 A THR 321 ? OG1 ? B THR 321 OG1 
41 1 Y 1 A THR 321 ? CG2 ? B THR 321 CG2 
42 1 Y 1 A LYS 322 ? CG  ? B LYS 322 CG  
43 1 Y 1 A LYS 322 ? CD  ? B LYS 322 CD  
44 1 Y 1 A LYS 322 ? CE  ? B LYS 322 CE  
45 1 Y 1 A LYS 322 ? NZ  ? B LYS 322 NZ  
46 1 Y 1 A PHE 368 ? CG  ? B PHE 368 CG  
47 1 Y 1 A PHE 368 ? CD1 ? B PHE 368 CD1 
48 1 Y 1 A PHE 368 ? CD2 ? B PHE 368 CD2 
49 1 Y 1 A PHE 368 ? CE1 ? B PHE 368 CE1 
50 1 Y 1 A PHE 368 ? CE2 ? B PHE 368 CE2 
51 1 Y 1 A PHE 368 ? CZ  ? B PHE 368 CZ  
52 1 Y 1 A TRP 372 ? CG  ? B TRP 372 CG  
53 1 Y 1 A TRP 372 ? CD1 ? B TRP 372 CD1 
54 1 Y 1 A TRP 372 ? CD2 ? B TRP 372 CD2 
55 1 Y 1 A TRP 372 ? NE1 ? B TRP 372 NE1 
56 1 Y 1 A TRP 372 ? CE2 ? B TRP 372 CE2 
57 1 Y 1 A TRP 372 ? CE3 ? B TRP 372 CE3 
58 1 Y 1 A TRP 372 ? CZ2 ? B TRP 372 CZ2 
59 1 Y 1 A TRP 372 ? CZ3 ? B TRP 372 CZ3 
60 1 Y 1 A TRP 372 ? CH2 ? B TRP 372 CH2 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Y5Z 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8Y5Z 
_struct.title                        'human NaS1 inward state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Y5Z 
_struct_keywords.text            'membrane sodium anion transproter, PROTEIN TRANSPORT' 
_struct_keywords.pdbx_keywords   'PROTEIN TRANSPORT' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 2 ? 
F N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    S13A1_HUMAN 
_struct_ref.pdbx_db_accession          Q9BZW2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASA
YFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIIN
AEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT
CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGK
TKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIP
AKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM
VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIV
GVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP
;
_struct_ref.pdbx_align_begin           0 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8Y5Z B 1 ? 595 ? Q9BZW2 1 ? 595 ? 1 595 
2 1 8Y5Z A 1 ? 595 ? Q9BZW2 1 ? 595 ? 1 595 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 2   ? TYR A 10  ? LYS B 2   TYR B 10  1 ? 9  
HELX_P HELX_P2  AA2 TYR A 10  ? LEU A 23  ? TYR B 10  LEU B 23  1 ? 14 
HELX_P HELX_P3  AA3 LEU A 24  ? VAL A 29  ? LEU B 24  VAL B 29  1 ? 6  
HELX_P HELX_P4  AA4 THR A 32  ? GLU A 51  ? THR B 32  GLU B 51  1 ? 20 
HELX_P HELX_P5  AA5 PRO A 54  ? LEU A 61  ? PRO B 54  LEU B 61  1 ? 8  
HELX_P HELX_P6  AA6 LEU A 64  ? PHE A 69  ? LEU B 64  PHE B 69  1 ? 6  
HELX_P HELX_P7  AA7 LYS A 83  ? TRP A 102 ? LYS B 83  TRP B 102 1 ? 20 
HELX_P HELX_P8  AA8 ASN A 103 ? GLY A 117 ? ASN B 103 GLY B 117 1 ? 15 
HELX_P HELX_P9  AA9 ASN A 119 ? LEU A 138 ? ASN B 119 LEU B 138 1 ? 20 
HELX_P HELX_P10 AB1 SER A 139 ? ASN A 160 ? SER B 139 ASN B 160 1 ? 22 
HELX_P HELX_P11 AB2 LYS A 231 ? LEU A 253 ? LYS B 231 LEU B 253 1 ? 23 
HELX_P HELX_P12 AB3 THR A 255 ? GLY A 258 ? THR B 255 GLY B 258 5 ? 4  
HELX_P HELX_P13 AB4 THR A 259 ? TYR A 273 ? THR B 259 TYR B 273 1 ? 15 
HELX_P HELX_P14 AB5 ASN A 280 ? LEU A 308 ? ASN B 280 LEU B 308 1 ? 29 
HELX_P HELX_P15 AB6 ASN A 311 ? PHE A 316 ? ASN B 311 PHE B 316 1 ? 6  
HELX_P HELX_P16 AB7 THR A 323 ? GLY A 341 ? THR B 323 GLY B 341 1 ? 19 
HELX_P HELX_P17 AB8 ARG A 344 ? LEU A 359 ? ARG B 344 LEU B 359 1 ? 16 
HELX_P HELX_P18 AB9 THR A 384 ? LEU A 394 ? THR B 384 LEU B 394 1 ? 11 
HELX_P HELX_P19 AC1 LEU A 395 ? LEU A 398 ? LEU B 395 LEU B 398 5 ? 4  
HELX_P HELX_P20 AC2 ILE A 413 ? ASP A 417 ? ILE B 413 ASP B 417 5 ? 5  
HELX_P HELX_P21 AC3 THR A 423 ? SER A 429 ? THR B 423 SER B 429 1 ? 7  
HELX_P HELX_P22 AC4 PRO A 432 ? CYS A 449 ? PRO B 432 CYS B 449 1 ? 18 
HELX_P HELX_P23 AC5 GLY A 453 ? ASN A 460 ? GLY B 453 ASN B 460 1 ? 8  
HELX_P HELX_P24 AC6 LYS A 461 ? SER A 463 ? LYS B 461 SER B 463 5 ? 3  
HELX_P HELX_P25 AC7 PRO A 469 ? GLU A 486 ? PRO B 469 GLU B 486 1 ? 18 
HELX_P HELX_P26 AC8 SER A 489 ? ILE A 508 ? SER B 489 ILE B 508 1 ? 20 
HELX_P HELX_P27 AC9 ASN A 511 ? SER A 524 ? ASN B 511 SER B 524 1 ? 14 
HELX_P HELX_P28 AD1 ASN A 533 ? TYR A 542 ? ASN B 533 TYR B 542 1 ? 10 
HELX_P HELX_P29 AD2 LYS A 546 ? TRP A 572 ? LYS B 546 TRP B 572 1 ? 27 
HELX_P HELX_P30 AD3 TRP A 572 ? ASP A 578 ? TRP B 572 ASP B 578 1 ? 7  
HELX_P HELX_P31 AD4 PHE B 3   ? TYR B 10  ? PHE A 3   TYR A 10  1 ? 8  
HELX_P HELX_P32 AD5 TYR B 10  ? LEU B 23  ? TYR A 10  LEU A 23  1 ? 14 
HELX_P HELX_P33 AD6 LEU B 24  ? VAL B 29  ? LEU A 24  VAL A 29  1 ? 6  
HELX_P HELX_P34 AD7 THR B 32  ? GLU B 51  ? THR A 32  GLU A 51  1 ? 20 
HELX_P HELX_P35 AD8 PRO B 54  ? LEU B 61  ? PRO A 54  LEU A 61  1 ? 8  
HELX_P HELX_P36 AD9 LEU B 64  ? PHE B 69  ? LEU A 64  PHE A 69  1 ? 6  
HELX_P HELX_P37 AE1 LYS B 83  ? TRP B 102 ? LYS A 83  TRP A 102 1 ? 20 
HELX_P HELX_P38 AE2 ASN B 103 ? GLY B 117 ? ASN A 103 GLY A 117 1 ? 15 
HELX_P HELX_P39 AE3 ASN B 119 ? LEU B 138 ? ASN A 119 LEU A 138 1 ? 20 
HELX_P HELX_P40 AE4 SER B 139 ? ASN B 160 ? SER A 139 ASN A 160 1 ? 22 
HELX_P HELX_P41 AE5 LYS B 231 ? LEU B 253 ? LYS A 231 LEU A 253 1 ? 23 
HELX_P HELX_P42 AE6 THR B 255 ? GLY B 258 ? THR A 255 GLY A 258 5 ? 4  
HELX_P HELX_P43 AE7 THR B 259 ? TYR B 273 ? THR A 259 TYR A 273 1 ? 15 
HELX_P HELX_P44 AE8 ASN B 280 ? LEU B 308 ? ASN A 280 LEU A 308 1 ? 29 
HELX_P HELX_P45 AE9 ASN B 311 ? PHE B 316 ? ASN A 311 PHE A 316 1 ? 6  
HELX_P HELX_P46 AF1 THR B 323 ? GLY B 341 ? THR A 323 GLY A 341 1 ? 19 
HELX_P HELX_P47 AF2 ARG B 344 ? LEU B 359 ? ARG A 344 LEU A 359 1 ? 16 
HELX_P HELX_P48 AF3 THR B 384 ? LEU B 394 ? THR A 384 LEU A 394 1 ? 11 
HELX_P HELX_P49 AF4 LEU B 395 ? LEU B 398 ? LEU A 395 LEU A 398 5 ? 4  
HELX_P HELX_P50 AF5 ILE B 413 ? ASP B 417 ? ILE A 413 ASP A 417 5 ? 5  
HELX_P HELX_P51 AF6 THR B 423 ? SER B 429 ? THR A 423 SER A 429 1 ? 7  
HELX_P HELX_P52 AF7 PRO B 432 ? CYS B 449 ? PRO A 432 CYS A 449 1 ? 18 
HELX_P HELX_P53 AF8 GLY B 453 ? ASN B 460 ? GLY A 453 ASN A 460 1 ? 8  
HELX_P HELX_P54 AF9 LYS B 461 ? SER B 463 ? LYS A 461 SER A 463 5 ? 3  
HELX_P HELX_P55 AG1 PRO B 469 ? GLU B 486 ? PRO A 469 GLU A 486 1 ? 18 
HELX_P HELX_P56 AG2 SER B 489 ? ILE B 508 ? SER A 489 ILE A 508 1 ? 20 
HELX_P HELX_P57 AG3 ASN B 511 ? SER B 524 ? ASN A 511 SER A 524 1 ? 14 
HELX_P HELX_P58 AG4 ASN B 533 ? TYR B 542 ? ASN A 533 TYR A 542 1 ? 10 
HELX_P HELX_P59 AG5 LYS B 546 ? TRP B 572 ? LYS A 546 TRP A 572 1 ? 27 
HELX_P HELX_P60 AG6 TRP B 572 ? ASP B 578 ? TRP A 572 ASP A 578 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A SER 135 O   ? ? ? 1_555 D NA . NA ? ? B SER 135 B NA 602 1_555 ? ? ? ? ? ? ? 2.943 ? ? 
metalc2  metalc ? ? A SER 135 OG  ? ? ? 1_555 D NA . NA ? ? B SER 135 B NA 602 1_555 ? ? ? ? ? ? ? 3.105 ? ? 
metalc3  metalc ? ? A LEU 138 O   ? ? ? 1_555 D NA . NA ? ? B LEU 138 B NA 602 1_555 ? ? ? ? ? ? ? 2.362 ? ? 
metalc4  metalc ? ? A ASN 140 OD1 ? ? ? 1_555 D NA . NA ? ? B ASN 140 B NA 602 1_555 ? ? ? ? ? ? ? 2.375 ? ? 
metalc5  metalc ? ? A GLY 258 O   ? ? ? 1_555 D NA . NA ? ? B GLY 258 B NA 602 1_555 ? ? ? ? ? ? ? 2.422 ? ? 
metalc6  metalc ? ? B SER 135 O   ? ? ? 1_555 F NA . NA ? ? A SER 135 A NA 602 1_555 ? ? ? ? ? ? ? 2.943 ? ? 
metalc7  metalc ? ? B SER 135 OG  ? ? ? 1_555 F NA . NA ? ? A SER 135 A NA 602 1_555 ? ? ? ? ? ? ? 3.104 ? ? 
metalc8  metalc ? ? B LEU 138 O   ? ? ? 1_555 F NA . NA ? ? A LEU 138 A NA 602 1_555 ? ? ? ? ? ? ? 2.361 ? ? 
metalc9  metalc ? ? B ASN 140 OD1 ? ? ? 1_555 F NA . NA ? ? A ASN 140 A NA 602 1_555 ? ? ? ? ? ? ? 2.374 ? ? 
metalc10 metalc ? ? B GLY 258 O   ? ? ? 1_555 F NA . NA ? ? A GLY 258 A NA 602 1_555 ? ? ? ? ? ? ? 2.423 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? A SER 135 ? B SER 135 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 OG  ? A SER 135 ? B SER 135 ? 1_555 53.2  ? 
2  O   ? A SER 135 ? B SER 135 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 O   ? A LEU 138 ? B LEU 138 ? 1_555 68.6  ? 
3  OG  ? A SER 135 ? B SER 135 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 O   ? A LEU 138 ? B LEU 138 ? 1_555 109.2 ? 
4  O   ? A SER 135 ? B SER 135 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 OD1 ? A ASN 140 ? B ASN 140 ? 1_555 99.4  ? 
5  OG  ? A SER 135 ? B SER 135 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 OD1 ? A ASN 140 ? B ASN 140 ? 1_555 54.1  ? 
6  O   ? A LEU 138 ? B LEU 138 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 OD1 ? A ASN 140 ? B ASN 140 ? 1_555 162.8 ? 
7  O   ? A SER 135 ? B SER 135 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 O   ? A GLY 258 ? B GLY 258 ? 1_555 101.5 ? 
8  OG  ? A SER 135 ? B SER 135 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 O   ? A GLY 258 ? B GLY 258 ? 1_555 120.9 ? 
9  O   ? A LEU 138 ? B LEU 138 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 O   ? A GLY 258 ? B GLY 258 ? 1_555 105.7 ? 
10 OD1 ? A ASN 140 ? B ASN 140 ? 1_555 NA ? D NA . ? B NA 602 ? 1_555 O   ? A GLY 258 ? B GLY 258 ? 1_555 88.3  ? 
11 O   ? B SER 135 ? A SER 135 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 OG  ? B SER 135 ? A SER 135 ? 1_555 53.2  ? 
12 O   ? B SER 135 ? A SER 135 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 O   ? B LEU 138 ? A LEU 138 ? 1_555 68.6  ? 
13 OG  ? B SER 135 ? A SER 135 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 O   ? B LEU 138 ? A LEU 138 ? 1_555 109.3 ? 
14 O   ? B SER 135 ? A SER 135 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 OD1 ? B ASN 140 ? A ASN 140 ? 1_555 99.5  ? 
15 OG  ? B SER 135 ? A SER 135 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 OD1 ? B ASN 140 ? A ASN 140 ? 1_555 54.3  ? 
16 O   ? B LEU 138 ? A LEU 138 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 OD1 ? B ASN 140 ? A ASN 140 ? 1_555 163.1 ? 
17 O   ? B SER 135 ? A SER 135 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 O   ? B GLY 258 ? A GLY 258 ? 1_555 101.5 ? 
18 OG  ? B SER 135 ? A SER 135 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 O   ? B GLY 258 ? A GLY 258 ? 1_555 120.9 ? 
19 O   ? B LEU 138 ? A LEU 138 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 O   ? B GLY 258 ? A GLY 258 ? 1_555 105.7 ? 
20 OD1 ? B ASN 140 ? A ASN 140 ? 1_555 NA ? F NA . ? A NA 602 ? 1_555 O   ? B GLY 258 ? A GLY 258 ? 1_555 88.1  ? 
# 
_pdbx_entry_details.entry_id                   8Y5Z 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR B 10  ? ? -95.82  57.53   
2  1 LYS B 75  ? ? 63.10   -166.13 
3  1 ALA B 80  ? ? 58.98   -118.79 
4  1 PHE B 82  ? ? 56.59   -166.66 
5  1 LEU B 360 ? ? 70.54   -7.43   
6  1 PHE B 368 ? ? -95.44  -60.76  
7  1 ALA B 415 ? ? 67.24   -5.80   
8  1 LEU B 421 ? ? 73.91   -11.90  
9  1 PHE B 430 ? ? 59.27   16.81   
10 1 CYS B 449 ? ? -90.97  49.29   
11 1 SER B 452 ? ? 62.37   -125.56 
12 1 PHE B 527 ? ? -90.33  45.81   
13 1 LEU B 528 ? ? -131.76 -39.72  
14 1 THR B 571 ? ? -95.36  -63.11  
15 1 TYR A 10  ? ? -95.78  57.42   
16 1 LYS A 75  ? ? 63.09   -166.14 
17 1 ALA A 80  ? ? 58.88   -118.75 
18 1 PHE A 82  ? ? 56.59   -166.58 
19 1 LEU A 360 ? ? 70.55   -7.36   
20 1 PHE A 368 ? ? -95.47  -60.73  
21 1 ALA A 415 ? ? 67.34   -5.82   
22 1 LEU A 421 ? ? 74.01   -11.98  
23 1 PHE A 430 ? ? 59.88   16.60   
24 1 CYS A 449 ? ? -91.00  49.23   
25 1 SER A 452 ? ? 62.32   -125.58 
26 1 PHE A 527 ? ? -90.50  44.27   
27 1 LEU A 528 ? ? -131.03 -38.50  
28 1 THR A 571 ? ? -95.39  -63.09  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8Y5Z 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8Y5Z 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.35 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               34318 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.2 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'membrane sodium anion transproter IN' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8Y5Z 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8Y5Z 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8Y5Z 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 B MET 1   ? A MET 1   
2   1 Y 1 B GLU 162 ? A GLU 162 
3   1 Y 1 B ALA 163 ? A ALA 163 
4   1 Y 1 B GLU 164 ? A GLU 164 
5   1 Y 1 B VAL 165 ? A VAL 165 
6   1 Y 1 B GLU 166 ? A GLU 166 
7   1 Y 1 B ALA 167 ? A ALA 167 
8   1 Y 1 B THR 168 ? A THR 168 
9   1 Y 1 B GLN 169 ? A GLN 169 
10  1 Y 1 B MET 170 ? A MET 170 
11  1 Y 1 B THR 171 ? A THR 171 
12  1 Y 1 B TYR 172 ? A TYR 172 
13  1 Y 1 B PHE 173 ? A PHE 173 
14  1 Y 1 B ASN 174 ? A ASN 174 
15  1 Y 1 B GLY 175 ? A GLY 175 
16  1 Y 1 B SER 176 ? A SER 176 
17  1 Y 1 B THR 177 ? A THR 177 
18  1 Y 1 B ASN 178 ? A ASN 178 
19  1 Y 1 B HIS 179 ? A HIS 179 
20  1 Y 1 B GLY 180 ? A GLY 180 
21  1 Y 1 B LEU 181 ? A LEU 181 
22  1 Y 1 B GLU 182 ? A GLU 182 
23  1 Y 1 B ILE 183 ? A ILE 183 
24  1 Y 1 B ASP 184 ? A ASP 184 
25  1 Y 1 B GLU 185 ? A GLU 185 
26  1 Y 1 B SER 186 ? A SER 186 
27  1 Y 1 B VAL 187 ? A VAL 187 
28  1 Y 1 B ASN 188 ? A ASN 188 
29  1 Y 1 B GLY 189 ? A GLY 189 
30  1 Y 1 B HIS 190 ? A HIS 190 
31  1 Y 1 B GLU 191 ? A GLU 191 
32  1 Y 1 B ILE 192 ? A ILE 192 
33  1 Y 1 B ASN 193 ? A ASN 193 
34  1 Y 1 B GLU 194 ? A GLU 194 
35  1 Y 1 B ARG 195 ? A ARG 195 
36  1 Y 1 B LYS 196 ? A LYS 196 
37  1 Y 1 B GLU 197 ? A GLU 197 
38  1 Y 1 B LYS 198 ? A LYS 198 
39  1 Y 1 B THR 199 ? A THR 199 
40  1 Y 1 B LYS 200 ? A LYS 200 
41  1 Y 1 B PRO 201 ? A PRO 201 
42  1 Y 1 B VAL 202 ? A VAL 202 
43  1 Y 1 B PRO 203 ? A PRO 203 
44  1 Y 1 B GLY 204 ? A GLY 204 
45  1 Y 1 B TYR 205 ? A TYR 205 
46  1 Y 1 B ASN 206 ? A ASN 206 
47  1 Y 1 B ASN 207 ? A ASN 207 
48  1 Y 1 B ASP 208 ? A ASP 208 
49  1 Y 1 B THR 209 ? A THR 209 
50  1 Y 1 B GLY 210 ? A GLY 210 
51  1 Y 1 B LYS 211 ? A LYS 211 
52  1 Y 1 B ILE 212 ? A ILE 212 
53  1 Y 1 B SER 213 ? A SER 213 
54  1 Y 1 B SER 214 ? A SER 214 
55  1 Y 1 B LYS 215 ? A LYS 215 
56  1 Y 1 B VAL 216 ? A VAL 216 
57  1 Y 1 B GLU 217 ? A GLU 217 
58  1 Y 1 B LEU 218 ? A LEU 218 
59  1 Y 1 B GLU 219 ? A GLU 219 
60  1 Y 1 B LYS 220 ? A LYS 220 
61  1 Y 1 B ASN 221 ? A ASN 221 
62  1 Y 1 B SER 222 ? A SER 222 
63  1 Y 1 B GLY 223 ? A GLY 223 
64  1 Y 1 B MET 224 ? A MET 224 
65  1 Y 1 B ARG 225 ? A ARG 225 
66  1 Y 1 B THR 226 ? A THR 226 
67  1 Y 1 B LYS 227 ? A LYS 227 
68  1 Y 1 B TYR 228 ? A TYR 228 
69  1 Y 1 B ARG 229 ? A ARG 229 
70  1 Y 1 B LYS 317 ? A LYS 317 
71  1 Y 1 B CYS 318 ? A CYS 318 
72  1 Y 1 B GLY 319 ? A GLY 319 
73  1 Y 1 B LYS 320 ? A LYS 320 
74  1 Y 1 B THR 405 ? A THR 405 
75  1 Y 1 B LYS 406 ? A LYS 406 
76  1 Y 1 B THR 407 ? A THR 407 
77  1 Y 1 B THR 408 ? A THR 408 
78  1 Y 1 B PRO 409 ? A PRO 409 
79  1 Y 1 B THR 410 ? A THR 410 
80  1 Y 1 B GLY 411 ? A GLY 411 
81  1 Y 1 B MET 589 ? A MET 589 
82  1 Y 1 B SER 590 ? A SER 590 
83  1 Y 1 B ASN 591 ? A ASN 591 
84  1 Y 1 B GLU 592 ? A GLU 592 
85  1 Y 1 B THR 593 ? A THR 593 
86  1 Y 1 B MET 594 ? A MET 594 
87  1 Y 1 B PRO 595 ? A PRO 595 
88  1 Y 1 A MET 1   ? B MET 1   
89  1 Y 1 A GLU 162 ? B GLU 162 
90  1 Y 1 A ALA 163 ? B ALA 163 
91  1 Y 1 A GLU 164 ? B GLU 164 
92  1 Y 1 A VAL 165 ? B VAL 165 
93  1 Y 1 A GLU 166 ? B GLU 166 
94  1 Y 1 A ALA 167 ? B ALA 167 
95  1 Y 1 A THR 168 ? B THR 168 
96  1 Y 1 A GLN 169 ? B GLN 169 
97  1 Y 1 A MET 170 ? B MET 170 
98  1 Y 1 A THR 171 ? B THR 171 
99  1 Y 1 A TYR 172 ? B TYR 172 
100 1 Y 1 A PHE 173 ? B PHE 173 
101 1 Y 1 A ASN 174 ? B ASN 174 
102 1 Y 1 A GLY 175 ? B GLY 175 
103 1 Y 1 A SER 176 ? B SER 176 
104 1 Y 1 A THR 177 ? B THR 177 
105 1 Y 1 A ASN 178 ? B ASN 178 
106 1 Y 1 A HIS 179 ? B HIS 179 
107 1 Y 1 A GLY 180 ? B GLY 180 
108 1 Y 1 A LEU 181 ? B LEU 181 
109 1 Y 1 A GLU 182 ? B GLU 182 
110 1 Y 1 A ILE 183 ? B ILE 183 
111 1 Y 1 A ASP 184 ? B ASP 184 
112 1 Y 1 A GLU 185 ? B GLU 185 
113 1 Y 1 A SER 186 ? B SER 186 
114 1 Y 1 A VAL 187 ? B VAL 187 
115 1 Y 1 A ASN 188 ? B ASN 188 
116 1 Y 1 A GLY 189 ? B GLY 189 
117 1 Y 1 A HIS 190 ? B HIS 190 
118 1 Y 1 A GLU 191 ? B GLU 191 
119 1 Y 1 A ILE 192 ? B ILE 192 
120 1 Y 1 A ASN 193 ? B ASN 193 
121 1 Y 1 A GLU 194 ? B GLU 194 
122 1 Y 1 A ARG 195 ? B ARG 195 
123 1 Y 1 A LYS 196 ? B LYS 196 
124 1 Y 1 A GLU 197 ? B GLU 197 
125 1 Y 1 A LYS 198 ? B LYS 198 
126 1 Y 1 A THR 199 ? B THR 199 
127 1 Y 1 A LYS 200 ? B LYS 200 
128 1 Y 1 A PRO 201 ? B PRO 201 
129 1 Y 1 A VAL 202 ? B VAL 202 
130 1 Y 1 A PRO 203 ? B PRO 203 
131 1 Y 1 A GLY 204 ? B GLY 204 
132 1 Y 1 A TYR 205 ? B TYR 205 
133 1 Y 1 A ASN 206 ? B ASN 206 
134 1 Y 1 A ASN 207 ? B ASN 207 
135 1 Y 1 A ASP 208 ? B ASP 208 
136 1 Y 1 A THR 209 ? B THR 209 
137 1 Y 1 A GLY 210 ? B GLY 210 
138 1 Y 1 A LYS 211 ? B LYS 211 
139 1 Y 1 A ILE 212 ? B ILE 212 
140 1 Y 1 A SER 213 ? B SER 213 
141 1 Y 1 A SER 214 ? B SER 214 
142 1 Y 1 A LYS 215 ? B LYS 215 
143 1 Y 1 A VAL 216 ? B VAL 216 
144 1 Y 1 A GLU 217 ? B GLU 217 
145 1 Y 1 A LEU 218 ? B LEU 218 
146 1 Y 1 A GLU 219 ? B GLU 219 
147 1 Y 1 A LYS 220 ? B LYS 220 
148 1 Y 1 A ASN 221 ? B ASN 221 
149 1 Y 1 A SER 222 ? B SER 222 
150 1 Y 1 A GLY 223 ? B GLY 223 
151 1 Y 1 A MET 224 ? B MET 224 
152 1 Y 1 A ARG 225 ? B ARG 225 
153 1 Y 1 A THR 226 ? B THR 226 
154 1 Y 1 A LYS 227 ? B LYS 227 
155 1 Y 1 A TYR 228 ? B TYR 228 
156 1 Y 1 A ARG 229 ? B ARG 229 
157 1 Y 1 A LYS 317 ? B LYS 317 
158 1 Y 1 A CYS 318 ? B CYS 318 
159 1 Y 1 A GLY 319 ? B GLY 319 
160 1 Y 1 A LYS 320 ? B LYS 320 
161 1 Y 1 A THR 405 ? B THR 405 
162 1 Y 1 A LYS 406 ? B LYS 406 
163 1 Y 1 A THR 407 ? B THR 407 
164 1 Y 1 A THR 408 ? B THR 408 
165 1 Y 1 A PRO 409 ? B PRO 409 
166 1 Y 1 A THR 410 ? B THR 410 
167 1 Y 1 A GLY 411 ? B GLY 411 
168 1 Y 1 A MET 589 ? B MET 589 
169 1 Y 1 A SER 590 ? B SER 590 
170 1 Y 1 A ASN 591 ? B ASN 591 
171 1 Y 1 A GLU 592 ? B GLU 592 
172 1 Y 1 A THR 593 ? B THR 593 
173 1 Y 1 A MET 594 ? B MET 594 
174 1 Y 1 A PRO 595 ? B PRO 595 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
NA  NA   NA N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
SO4 S    S  N N 302 
SO4 O1   O  N N 303 
SO4 O2   O  N N 304 
SO4 O3   O  N N 305 
SO4 O4   O  N N 306 
THR N    N  N N 307 
THR CA   C  N S 308 
THR C    C  N N 309 
THR O    O  N N 310 
THR CB   C  N R 311 
THR OG1  O  N N 312 
THR CG2  C  N N 313 
THR OXT  O  N N 314 
THR H    H  N N 315 
THR H2   H  N N 316 
THR HA   H  N N 317 
THR HB   H  N N 318 
THR HG1  H  N N 319 
THR HG21 H  N N 320 
THR HG22 H  N N 321 
THR HG23 H  N N 322 
THR HXT  H  N N 323 
TRP N    N  N N 324 
TRP CA   C  N S 325 
TRP C    C  N N 326 
TRP O    O  N N 327 
TRP CB   C  N N 328 
TRP CG   C  Y N 329 
TRP CD1  C  Y N 330 
TRP CD2  C  Y N 331 
TRP NE1  N  Y N 332 
TRP CE2  C  Y N 333 
TRP CE3  C  Y N 334 
TRP CZ2  C  Y N 335 
TRP CZ3  C  Y N 336 
TRP CH2  C  Y N 337 
TRP OXT  O  N N 338 
TRP H    H  N N 339 
TRP H2   H  N N 340 
TRP HA   H  N N 341 
TRP HB2  H  N N 342 
TRP HB3  H  N N 343 
TRP HD1  H  N N 344 
TRP HE1  H  N N 345 
TRP HE3  H  N N 346 
TRP HZ2  H  N N 347 
TRP HZ3  H  N N 348 
TRP HH2  H  N N 349 
TRP HXT  H  N N 350 
TYR N    N  N N 351 
TYR CA   C  N S 352 
TYR C    C  N N 353 
TYR O    O  N N 354 
TYR CB   C  N N 355 
TYR CG   C  Y N 356 
TYR CD1  C  Y N 357 
TYR CD2  C  Y N 358 
TYR CE1  C  Y N 359 
TYR CE2  C  Y N 360 
TYR CZ   C  Y N 361 
TYR OH   O  N N 362 
TYR OXT  O  N N 363 
TYR H    H  N N 364 
TYR H2   H  N N 365 
TYR HA   H  N N 366 
TYR HB2  H  N N 367 
TYR HB3  H  N N 368 
TYR HD1  H  N N 369 
TYR HD2  H  N N 370 
TYR HE1  H  N N 371 
TYR HE2  H  N N 372 
TYR HH   H  N N 373 
TYR HXT  H  N N 374 
VAL N    N  N N 375 
VAL CA   C  N S 376 
VAL C    C  N N 377 
VAL O    O  N N 378 
VAL CB   C  N N 379 
VAL CG1  C  N N 380 
VAL CG2  C  N N 381 
VAL OXT  O  N N 382 
VAL H    H  N N 383 
VAL H2   H  N N 384 
VAL HA   H  N N 385 
VAL HB   H  N N 386 
VAL HG11 H  N N 387 
VAL HG12 H  N N 388 
VAL HG13 H  N N 389 
VAL HG21 H  N N 390 
VAL HG22 H  N N 391 
VAL HG23 H  N N 392 
VAL HXT  H  N N 393 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
SO4 S   O1   doub N N 288 
SO4 S   O2   doub N N 289 
SO4 S   O3   sing N N 290 
SO4 S   O4   sing N N 291 
THR N   CA   sing N N 292 
THR N   H    sing N N 293 
THR N   H2   sing N N 294 
THR CA  C    sing N N 295 
THR CA  CB   sing N N 296 
THR CA  HA   sing N N 297 
THR C   O    doub N N 298 
THR C   OXT  sing N N 299 
THR CB  OG1  sing N N 300 
THR CB  CG2  sing N N 301 
THR CB  HB   sing N N 302 
THR OG1 HG1  sing N N 303 
THR CG2 HG21 sing N N 304 
THR CG2 HG22 sing N N 305 
THR CG2 HG23 sing N N 306 
THR OXT HXT  sing N N 307 
TRP N   CA   sing N N 308 
TRP N   H    sing N N 309 
TRP N   H2   sing N N 310 
TRP CA  C    sing N N 311 
TRP CA  CB   sing N N 312 
TRP CA  HA   sing N N 313 
TRP C   O    doub N N 314 
TRP C   OXT  sing N N 315 
TRP CB  CG   sing N N 316 
TRP CB  HB2  sing N N 317 
TRP CB  HB3  sing N N 318 
TRP CG  CD1  doub Y N 319 
TRP CG  CD2  sing Y N 320 
TRP CD1 NE1  sing Y N 321 
TRP CD1 HD1  sing N N 322 
TRP CD2 CE2  doub Y N 323 
TRP CD2 CE3  sing Y N 324 
TRP NE1 CE2  sing Y N 325 
TRP NE1 HE1  sing N N 326 
TRP CE2 CZ2  sing Y N 327 
TRP CE3 CZ3  doub Y N 328 
TRP CE3 HE3  sing N N 329 
TRP CZ2 CH2  doub Y N 330 
TRP CZ2 HZ2  sing N N 331 
TRP CZ3 CH2  sing Y N 332 
TRP CZ3 HZ3  sing N N 333 
TRP CH2 HH2  sing N N 334 
TRP OXT HXT  sing N N 335 
TYR N   CA   sing N N 336 
TYR N   H    sing N N 337 
TYR N   H2   sing N N 338 
TYR CA  C    sing N N 339 
TYR CA  CB   sing N N 340 
TYR CA  HA   sing N N 341 
TYR C   O    doub N N 342 
TYR C   OXT  sing N N 343 
TYR CB  CG   sing N N 344 
TYR CB  HB2  sing N N 345 
TYR CB  HB3  sing N N 346 
TYR CG  CD1  doub Y N 347 
TYR CG  CD2  sing Y N 348 
TYR CD1 CE1  sing Y N 349 
TYR CD1 HD1  sing N N 350 
TYR CD2 CE2  doub Y N 351 
TYR CD2 HD2  sing N N 352 
TYR CE1 CZ   doub Y N 353 
TYR CE1 HE1  sing N N 354 
TYR CE2 CZ   sing Y N 355 
TYR CE2 HE2  sing N N 356 
TYR CZ  OH   sing N N 357 
TYR OH  HH   sing N N 358 
TYR OXT HXT  sing N N 359 
VAL N   CA   sing N N 360 
VAL N   H    sing N N 361 
VAL N   H2   sing N N 362 
VAL CA  C    sing N N 363 
VAL CA  CB   sing N N 364 
VAL CA  HA   sing N N 365 
VAL C   O    doub N N 366 
VAL C   OXT  sing N N 367 
VAL CB  CG1  sing N N 368 
VAL CB  CG2  sing N N 369 
VAL CB  HB   sing N N 370 
VAL CG1 HG11 sing N N 371 
VAL CG1 HG12 sing N N 372 
VAL CG1 HG13 sing N N 373 
VAL CG2 HG21 sing N N 374 
VAL CG2 HG22 sing N N 375 
VAL CG2 HG23 sing N N 376 
VAL OXT HXT  sing N N 377 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-02-01 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8Y5Z 
_em_admin.last_update        2025-01-22 
_em_admin.map_release_date   2025-01-22 
_em_admin.title              'human NaS1 inward state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32030056 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8Y5Z 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
N  
NA 
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . LYS A 1 2   ? 162.578 115.748 145.479 1.00 108.94 ? 2   LYS B N   1 
ATOM   2    C  CA  . LYS A 1 2   ? 161.170 116.119 145.412 1.00 108.94 ? 2   LYS B CA  1 
ATOM   3    C  C   . LYS A 1 2   ? 160.716 116.238 143.959 1.00 108.94 ? 2   LYS B C   1 
ATOM   4    O  O   . LYS A 1 2   ? 159.549 116.511 143.681 1.00 108.94 ? 2   LYS B O   1 
ATOM   5    C  CB  . LYS A 1 2   ? 160.926 117.433 146.157 1.00 108.94 ? 2   LYS B CB  1 
ATOM   6    C  CG  . LYS A 1 2   ? 159.494 117.628 146.628 1.00 108.94 ? 2   LYS B CG  1 
ATOM   7    C  CD  . LYS A 1 2   ? 159.105 116.577 147.654 1.00 108.94 ? 2   LYS B CD  1 
ATOM   8    C  CE  . LYS A 1 2   ? 157.706 116.821 148.193 1.00 108.94 ? 2   LYS B CE  1 
ATOM   9    N  NZ  . LYS A 1 2   ? 157.296 115.772 149.167 1.00 108.94 ? 2   LYS B NZ  1 
ATOM   10   N  N   . PHE A 1 3   ? 161.655 116.028 143.034 1.00 110.85 ? 3   PHE B N   1 
ATOM   11   C  CA  . PHE A 1 3   ? 161.325 116.104 141.615 1.00 110.85 ? 3   PHE B CA  1 
ATOM   12   C  C   . PHE A 1 3   ? 160.352 115.007 141.204 1.00 110.85 ? 3   PHE B C   1 
ATOM   13   O  O   . PHE A 1 3   ? 159.490 115.233 140.346 1.00 110.85 ? 3   PHE B O   1 
ATOM   14   C  CB  . PHE A 1 3   ? 162.600 116.019 140.776 1.00 110.85 ? 3   PHE B CB  1 
ATOM   15   C  CG  . PHE A 1 3   ? 163.511 117.201 140.938 1.00 110.85 ? 3   PHE B CG  1 
ATOM   16   C  CD1 . PHE A 1 3   ? 163.267 118.379 140.253 1.00 110.85 ? 3   PHE B CD1 1 
ATOM   17   C  CD2 . PHE A 1 3   ? 164.610 117.135 141.777 1.00 110.85 ? 3   PHE B CD2 1 
ATOM   18   C  CE1 . PHE A 1 3   ? 164.104 119.469 140.400 1.00 110.85 ? 3   PHE B CE1 1 
ATOM   19   C  CE2 . PHE A 1 3   ? 165.451 118.221 141.930 1.00 110.85 ? 3   PHE B CE2 1 
ATOM   20   C  CZ  . PHE A 1 3   ? 165.197 119.390 141.240 1.00 110.85 ? 3   PHE B CZ  1 
ATOM   21   N  N   . PHE A 1 4   ? 160.478 113.817 141.797 1.00 109.92 ? 4   PHE B N   1 
ATOM   22   C  CA  . PHE A 1 4   ? 159.620 112.700 141.416 1.00 109.92 ? 4   PHE B CA  1 
ATOM   23   C  C   . PHE A 1 4   ? 158.156 113.001 141.712 1.00 109.92 ? 4   PHE B C   1 
ATOM   24   O  O   . PHE A 1 4   ? 157.284 112.784 140.862 1.00 109.92 ? 4   PHE B O   1 
ATOM   25   C  CB  . PHE A 1 4   ? 160.063 111.433 142.146 1.00 109.92 ? 4   PHE B CB  1 
ATOM   26   C  CG  . PHE A 1 4   ? 161.404 110.914 141.707 1.00 109.92 ? 4   PHE B CG  1 
ATOM   27   C  CD1 . PHE A 1 4   ? 161.993 111.368 140.538 1.00 109.92 ? 4   PHE B CD1 1 
ATOM   28   C  CD2 . PHE A 1 4   ? 162.081 109.979 142.472 1.00 109.92 ? 4   PHE B CD2 1 
ATOM   29   C  CE1 . PHE A 1 4   ? 163.228 110.894 140.137 1.00 109.92 ? 4   PHE B CE1 1 
ATOM   30   C  CE2 . PHE A 1 4   ? 163.317 109.501 142.076 1.00 109.92 ? 4   PHE B CE2 1 
ATOM   31   C  CZ  . PHE A 1 4   ? 163.890 109.959 140.907 1.00 109.92 ? 4   PHE B CZ  1 
ATOM   32   N  N   . SER A 1 5   ? 157.869 113.511 142.912 1.00 105.80 ? 5   SER B N   1 
ATOM   33   C  CA  . SER A 1 5   ? 156.494 113.849 143.264 1.00 105.80 ? 5   SER B CA  1 
ATOM   34   C  C   . SER A 1 5   ? 155.958 114.971 142.384 1.00 105.80 ? 5   SER B C   1 
ATOM   35   O  O   . SER A 1 5   ? 154.798 114.933 141.958 1.00 105.80 ? 5   SER B O   1 
ATOM   36   C  CB  . SER A 1 5   ? 156.411 114.238 144.740 1.00 105.80 ? 5   SER B CB  1 
ATOM   37   O  OG  . SER A 1 5   ? 155.084 114.573 145.105 1.00 105.80 ? 5   SER B OG  1 
ATOM   38   N  N   . TYR A 1 6   ? 156.787 115.979 142.104 1.00 102.60 ? 6   TYR B N   1 
ATOM   39   C  CA  . TYR A 1 6   ? 156.344 117.087 141.265 1.00 102.60 ? 6   TYR B CA  1 
ATOM   40   C  C   . TYR A 1 6   ? 156.003 116.610 139.859 1.00 102.60 ? 6   TYR B C   1 
ATOM   41   O  O   . TYR A 1 6   ? 155.007 117.047 139.271 1.00 102.60 ? 6   TYR B O   1 
ATOM   42   C  CB  . TYR A 1 6   ? 157.419 118.172 141.222 1.00 102.60 ? 6   TYR B CB  1 
ATOM   43   C  CG  . TYR A 1 6   ? 157.422 119.080 142.433 1.00 102.60 ? 6   TYR B CG  1 
ATOM   44   C  CD1 . TYR A 1 6   ? 156.595 118.824 143.519 1.00 102.60 ? 6   TYR B CD1 1 
ATOM   45   C  CD2 . TYR A 1 6   ? 158.255 120.189 142.491 1.00 102.60 ? 6   TYR B CD2 1 
ATOM   46   C  CE1 . TYR A 1 6   ? 156.597 119.649 144.628 1.00 102.60 ? 6   TYR B CE1 1 
ATOM   47   C  CE2 . TYR A 1 6   ? 158.264 121.020 143.596 1.00 102.60 ? 6   TYR B CE2 1 
ATOM   48   C  CZ  . TYR A 1 6   ? 157.432 120.745 144.661 1.00 102.60 ? 6   TYR B CZ  1 
ATOM   49   O  OH  . TYR A 1 6   ? 157.437 121.569 145.763 1.00 102.60 ? 6   TYR B OH  1 
ATOM   50   N  N   . ILE A 1 7   ? 156.820 115.713 139.303 1.00 97.60  ? 7   ILE B N   1 
ATOM   51   C  CA  . ILE A 1 7   ? 156.519 115.151 137.990 1.00 97.60  ? 7   ILE B CA  1 
ATOM   52   C  C   . ILE A 1 7   ? 155.241 114.325 138.045 1.00 97.60  ? 7   ILE B C   1 
ATOM   53   O  O   . ILE A 1 7   ? 154.388 114.414 137.153 1.00 97.60  ? 7   ILE B O   1 
ATOM   54   C  CB  . ILE A 1 7   ? 157.711 114.320 137.478 1.00 97.60  ? 7   ILE B CB  1 
ATOM   55   C  CG1 . ILE A 1 7   ? 158.889 115.232 137.130 1.00 97.60  ? 7   ILE B CG1 1 
ATOM   56   C  CG2 . ILE A 1 7   ? 157.305 113.489 136.272 1.00 97.60  ? 7   ILE B CG2 1 
ATOM   57   C  CD1 . ILE A 1 7   ? 158.519 116.396 136.239 1.00 97.60  ? 7   ILE B CD1 1 
ATOM   58   N  N   . LEU A 1 8   ? 155.081 113.516 139.095 1.00 94.93  ? 8   LEU B N   1 
ATOM   59   C  CA  . LEU A 1 8   ? 153.900 112.669 139.211 1.00 94.93  ? 8   LEU B CA  1 
ATOM   60   C  C   . LEU A 1 8   ? 152.630 113.475 139.456 1.00 94.93  ? 8   LEU B C   1 
ATOM   61   O  O   . LEU A 1 8   ? 151.531 112.961 139.225 1.00 94.93  ? 8   LEU B O   1 
ATOM   62   C  CB  . LEU A 1 8   ? 154.117 111.636 140.323 1.00 94.93  ? 8   LEU B CB  1 
ATOM   63   C  CG  . LEU A 1 8   ? 153.133 110.480 140.535 1.00 94.93  ? 8   LEU B CG  1 
ATOM   64   C  CD1 . LEU A 1 8   ? 153.873 109.277 141.091 1.00 94.93  ? 8   LEU B CD1 1 
ATOM   65   C  CD2 . LEU A 1 8   ? 152.006 110.863 141.482 1.00 94.93  ? 8   LEU B CD2 1 
ATOM   66   N  N   . VAL A 1 9   ? 152.748 114.721 139.911 1.00 89.75  ? 9   VAL B N   1 
ATOM   67   C  CA  . VAL A 1 9   ? 151.560 115.541 140.126 1.00 89.75  ? 9   VAL B CA  1 
ATOM   68   C  C   . VAL A 1 9   ? 151.132 116.223 138.832 1.00 89.75  ? 9   VAL B C   1 
ATOM   69   O  O   . VAL A 1 9   ? 149.964 116.152 138.432 1.00 89.75  ? 9   VAL B O   1 
ATOM   70   C  CB  . VAL A 1 9   ? 151.809 116.566 141.247 1.00 89.75  ? 9   VAL B CB  1 
ATOM   71   C  CG1 . VAL A 1 9   ? 150.750 117.654 141.211 1.00 89.75  ? 9   VAL B CG1 1 
ATOM   72   C  CG2 . VAL A 1 9   ? 151.813 115.877 142.600 1.00 89.75  ? 9   VAL B CG2 1 
ATOM   73   N  N   . TYR A 1 10  ? 152.063 116.893 138.161 1.00 81.81  ? 10  TYR B N   1 
ATOM   74   C  CA  . TYR A 1 10  ? 151.758 117.629 136.933 1.00 81.81  ? 10  TYR B CA  1 
ATOM   75   C  C   . TYR A 1 10  ? 152.067 116.781 135.700 1.00 81.81  ? 10  TYR B C   1 
ATOM   76   O  O   . TYR A 1 10  ? 152.850 117.160 134.831 1.00 81.81  ? 10  TYR B O   1 
ATOM   77   C  CB  . TYR A 1 10  ? 152.531 118.945 136.901 1.00 81.81  ? 10  TYR B CB  1 
ATOM   78   C  CG  . TYR A 1 10  ? 152.299 119.830 138.104 1.00 81.81  ? 10  TYR B CG  1 
ATOM   79   C  CD1 . TYR A 1 10  ? 153.044 119.667 139.263 1.00 81.81  ? 10  TYR B CD1 1 
ATOM   80   C  CD2 . TYR A 1 10  ? 151.336 120.828 138.079 1.00 81.81  ? 10  TYR B CD2 1 
ATOM   81   C  CE1 . TYR A 1 10  ? 152.835 120.473 140.364 1.00 81.81  ? 10  TYR B CE1 1 
ATOM   82   C  CE2 . TYR A 1 10  ? 151.120 121.638 139.175 1.00 81.81  ? 10  TYR B CE2 1 
ATOM   83   C  CZ  . TYR A 1 10  ? 151.872 121.457 140.315 1.00 81.81  ? 10  TYR B CZ  1 
ATOM   84   O  OH  . TYR A 1 10  ? 151.661 122.262 141.410 1.00 81.81  ? 10  TYR B OH  1 
ATOM   85   N  N   . ARG A 1 11  ? 151.433 115.609 135.627 1.00 75.52  ? 11  ARG B N   1 
ATOM   86   C  CA  . ARG A 1 11  ? 151.597 114.774 134.442 1.00 75.52  ? 11  ARG B CA  1 
ATOM   87   C  C   . ARG A 1 11  ? 150.845 115.344 133.250 1.00 75.52  ? 11  ARG B C   1 
ATOM   88   O  O   . ARG A 1 11  ? 151.292 115.193 132.110 1.00 75.52  ? 11  ARG B O   1 
ATOM   89   C  CB  . ARG A 1 11  ? 151.124 113.348 134.715 1.00 75.52  ? 11  ARG B CB  1 
ATOM   90   C  CG  . ARG A 1 11  ? 151.413 112.839 136.108 1.00 75.52  ? 11  ARG B CG  1 
ATOM   91   C  CD  . ARG A 1 11  ? 150.421 111.759 136.500 1.00 75.52  ? 11  ARG B CD  1 
ATOM   92   N  NE  . ARG A 1 11  ? 149.048 112.245 136.458 1.00 75.52  ? 11  ARG B NE  1 
ATOM   93   C  CZ  . ARG A 1 11  ? 147.995 111.490 136.179 1.00 75.52  ? 11  ARG B CZ  1 
ATOM   94   N  NH1 . ARG A 1 11  ? 148.120 110.201 135.910 1.00 75.52  ? 11  ARG B NH1 1 
ATOM   95   N  NH2 . ARG A 1 11  ? 146.785 112.042 136.170 1.00 75.52  ? 11  ARG B NH2 1 
ATOM   96   N  N   . ARG A 1 12  ? 149.708 115.996 133.492 1.00 70.57  ? 12  ARG B N   1 
ATOM   97   C  CA  . ARG A 1 12  ? 148.872 116.482 132.400 1.00 70.57  ? 12  ARG B CA  1 
ATOM   98   C  C   . ARG A 1 12  ? 149.568 117.588 131.615 1.00 70.57  ? 12  ARG B C   1 
ATOM   99   O  O   . ARG A 1 12  ? 149.662 117.526 130.383 1.00 70.57  ? 12  ARG B O   1 
ATOM   100  C  CB  . ARG A 1 12  ? 147.542 116.970 132.972 1.00 70.57  ? 12  ARG B CB  1 
ATOM   101  C  CG  . ARG A 1 12  ? 146.477 117.299 131.955 1.00 70.57  ? 12  ARG B CG  1 
ATOM   102  C  CD  . ARG A 1 12  ? 145.185 117.679 132.661 1.00 70.57  ? 12  ARG B CD  1 
ATOM   103  N  NE  . ARG A 1 12  ? 144.657 116.573 133.450 1.00 70.57  ? 12  ARG B NE  1 
ATOM   104  C  CZ  . ARG A 1 12  ? 144.591 116.563 134.774 1.00 70.57  ? 12  ARG B CZ  1 
ATOM   105  N  NH1 . ARG A 1 12  ? 145.004 117.592 135.495 1.00 70.57  ? 12  ARG B NH1 1 
ATOM   106  N  NH2 . ARG A 1 12  ? 144.098 115.493 135.391 1.00 70.57  ? 12  ARG B NH2 1 
ATOM   107  N  N   . PHE A 1 13  ? 150.071 118.605 132.316 1.00 64.98  ? 13  PHE B N   1 
ATOM   108  C  CA  . PHE A 1 13  ? 150.750 119.717 131.656 1.00 64.98  ? 13  PHE B CA  1 
ATOM   109  C  C   . PHE A 1 13  ? 152.006 119.243 130.935 1.00 64.98  ? 13  PHE B C   1 
ATOM   110  O  O   . PHE A 1 13  ? 152.257 119.615 129.779 1.00 64.98  ? 13  PHE B O   1 
ATOM   111  C  CB  . PHE A 1 13  ? 151.088 120.788 132.695 1.00 64.98  ? 13  PHE B CB  1 
ATOM   112  C  CG  . PHE A 1 13  ? 151.695 122.034 132.123 1.00 64.98  ? 13  PHE B CG  1 
ATOM   113  C  CD1 . PHE A 1 13  ? 153.067 122.152 131.988 1.00 64.98  ? 13  PHE B CD1 1 
ATOM   114  C  CD2 . PHE A 1 13  ? 150.898 123.098 131.744 1.00 64.98  ? 13  PHE B CD2 1 
ATOM   115  C  CE1 . PHE A 1 13  ? 153.629 123.298 131.471 1.00 64.98  ? 13  PHE B CE1 1 
ATOM   116  C  CE2 . PHE A 1 13  ? 151.456 124.247 131.229 1.00 64.98  ? 13  PHE B CE2 1 
ATOM   117  C  CZ  . PHE A 1 13  ? 152.822 124.348 131.091 1.00 64.98  ? 13  PHE B CZ  1 
ATOM   118  N  N   . LEU A 1 14  ? 152.806 118.413 131.607 1.00 66.15  ? 14  LEU B N   1 
ATOM   119  C  CA  . LEU A 1 14  ? 154.034 117.915 131.002 1.00 66.15  ? 14  LEU B CA  1 
ATOM   120  C  C   . LEU A 1 14  ? 153.737 117.077 129.768 1.00 66.15  ? 14  LEU B C   1 
ATOM   121  O  O   . LEU A 1 14  ? 154.426 117.196 128.750 1.00 66.15  ? 14  LEU B O   1 
ATOM   122  C  CB  . LEU A 1 14  ? 154.832 117.103 132.022 1.00 66.15  ? 14  LEU B CB  1 
ATOM   123  C  CG  . LEU A 1 14  ? 155.901 117.853 132.818 1.00 66.15  ? 14  LEU B CG  1 
ATOM   124  C  CD1 . LEU A 1 14  ? 156.989 118.362 131.885 1.00 66.15  ? 14  LEU B CD1 1 
ATOM   125  C  CD2 . LEU A 1 14  ? 155.302 118.996 133.621 1.00 66.15  ? 14  LEU B CD2 1 
ATOM   126  N  N   . PHE A 1 15  ? 152.711 116.226 129.837 1.00 62.68  ? 15  PHE B N   1 
ATOM   127  C  CA  . PHE A 1 15  ? 152.373 115.396 128.689 1.00 62.68  ? 15  PHE B CA  1 
ATOM   128  C  C   . PHE A 1 15  ? 151.859 116.235 127.529 1.00 62.68  ? 15  PHE B C   1 
ATOM   129  O  O   . PHE A 1 15  ? 152.187 115.957 126.373 1.00 62.68  ? 15  PHE B O   1 
ATOM   130  C  CB  . PHE A 1 15  ? 151.340 114.341 129.069 1.00 62.68  ? 15  PHE B CB  1 
ATOM   131  C  CG  . PHE A 1 15  ? 151.049 113.373 127.965 1.00 62.68  ? 15  PHE B CG  1 
ATOM   132  C  CD1 . PHE A 1 15  ? 152.082 112.727 127.310 1.00 62.68  ? 15  PHE B CD1 1 
ATOM   133  C  CD2 . PHE A 1 15  ? 149.750 113.126 127.563 1.00 62.68  ? 15  PHE B CD2 1 
ATOM   134  C  CE1 . PHE A 1 15  ? 151.825 111.839 126.287 1.00 62.68  ? 15  PHE B CE1 1 
ATOM   135  C  CE2 . PHE A 1 15  ? 149.488 112.241 126.537 1.00 62.68  ? 15  PHE B CE2 1 
ATOM   136  C  CZ  . PHE A 1 15  ? 150.526 111.596 125.900 1.00 62.68  ? 15  PHE B CZ  1 
ATOM   137  N  N   . VAL A 1 16  ? 151.046 117.255 127.810 1.00 61.98  ? 16  VAL B N   1 
ATOM   138  C  CA  . VAL A 1 16  ? 150.565 118.125 126.739 1.00 61.98  ? 16  VAL B CA  1 
ATOM   139  C  C   . VAL A 1 16  ? 151.739 118.806 126.050 1.00 61.98  ? 16  VAL B C   1 
ATOM   140  O  O   . VAL A 1 16  ? 151.838 118.821 124.815 1.00 61.98  ? 16  VAL B O   1 
ATOM   141  C  CB  . VAL A 1 16  ? 149.563 119.156 127.289 1.00 61.98  ? 16  VAL B CB  1 
ATOM   142  C  CG1 . VAL A 1 16  ? 149.353 120.275 126.286 1.00 61.98  ? 16  VAL B CG1 1 
ATOM   143  C  CG2 . VAL A 1 16  ? 148.248 118.491 127.623 1.00 61.98  ? 16  VAL B CG2 1 
ATOM   144  N  N   . VAL A 1 17  ? 152.659 119.362 126.843 1.00 66.13  ? 17  VAL B N   1 
ATOM   145  C  CA  . VAL A 1 17  ? 153.806 120.058 126.267 1.00 66.13  ? 17  VAL B CA  1 
ATOM   146  C  C   . VAL A 1 17  ? 154.666 119.094 125.458 1.00 66.13  ? 17  VAL B C   1 
ATOM   147  O  O   . VAL A 1 17  ? 155.091 119.409 124.338 1.00 66.13  ? 17  VAL B O   1 
ATOM   148  C  CB  . VAL A 1 17  ? 154.618 120.752 127.376 1.00 66.13  ? 17  VAL B CB  1 
ATOM   149  C  CG1 . VAL A 1 17  ? 155.983 121.169 126.857 1.00 66.13  ? 17  VAL B CG1 1 
ATOM   150  C  CG2 . VAL A 1 17  ? 153.856 121.951 127.910 1.00 66.13  ? 17  VAL B CG2 1 
ATOM   151  N  N   . PHE A 1 18  ? 154.929 117.905 126.005 1.00 66.39  ? 18  PHE B N   1 
ATOM   152  C  CA  . PHE A 1 18  ? 155.766 116.934 125.309 1.00 66.39  ? 18  PHE B CA  1 
ATOM   153  C  C   . PHE A 1 18  ? 155.124 116.475 124.008 1.00 66.39  ? 18  PHE B C   1 
ATOM   154  O  O   . PHE A 1 18  ? 155.801 116.367 122.980 1.00 66.39  ? 18  PHE B O   1 
ATOM   155  C  CB  . PHE A 1 18  ? 156.045 115.741 126.221 1.00 66.39  ? 18  PHE B CB  1 
ATOM   156  C  CG  . PHE A 1 18  ? 156.936 114.705 125.605 1.00 66.39  ? 18  PHE B CG  1 
ATOM   157  C  CD1 . PHE A 1 18  ? 158.128 115.069 125.003 1.00 66.39  ? 18  PHE B CD1 1 
ATOM   158  C  CD2 . PHE A 1 18  ? 156.584 113.367 125.629 1.00 66.39  ? 18  PHE B CD2 1 
ATOM   159  C  CE1 . PHE A 1 18  ? 158.953 114.118 124.435 1.00 66.39  ? 18  PHE B CE1 1 
ATOM   160  C  CE2 . PHE A 1 18  ? 157.404 112.411 125.063 1.00 66.39  ? 18  PHE B CE2 1 
ATOM   161  C  CZ  . PHE A 1 18  ? 158.590 112.787 124.465 1.00 66.39  ? 18  PHE B CZ  1 
ATOM   162  N  N   . THR A 1 19  ? 153.819 116.191 124.032 1.00 64.87  ? 19  THR B N   1 
ATOM   163  C  CA  . THR A 1 19  ? 153.134 115.756 122.821 1.00 64.87  ? 19  THR B CA  1 
ATOM   164  C  C   . THR A 1 19  ? 153.153 116.845 121.761 1.00 64.87  ? 19  THR B C   1 
ATOM   165  O  O   . THR A 1 19  ? 153.358 116.562 120.575 1.00 64.87  ? 19  THR B O   1 
ATOM   166  C  CB  . THR A 1 19  ? 151.695 115.353 123.145 1.00 64.87  ? 19  THR B CB  1 
ATOM   167  O  OG1 . THR A 1 19  ? 151.700 114.276 124.090 1.00 64.87  ? 19  THR B OG1 1 
ATOM   168  C  CG2 . THR A 1 19  ? 150.971 114.907 121.887 1.00 64.87  ? 19  THR B CG2 1 
ATOM   169  N  N   . VAL A 1 20  ? 152.945 118.099 122.168 1.00 64.95  ? 20  VAL B N   1 
ATOM   170  C  CA  . VAL A 1 20  ? 152.984 119.195 121.205 1.00 64.95  ? 20  VAL B CA  1 
ATOM   171  C  C   . VAL A 1 20  ? 154.376 119.319 120.597 1.00 64.95  ? 20  VAL B C   1 
ATOM   172  O  O   . VAL A 1 20  ? 154.529 119.449 119.377 1.00 64.95  ? 20  VAL B O   1 
ATOM   173  C  CB  . VAL A 1 20  ? 152.537 120.510 121.868 1.00 64.95  ? 20  VAL B CB  1 
ATOM   174  C  CG1 . VAL A 1 20  ? 152.894 121.694 120.991 1.00 64.95  ? 20  VAL B CG1 1 
ATOM   175  C  CG2 . VAL A 1 20  ? 151.044 120.482 122.135 1.00 64.95  ? 20  VAL B CG2 1 
ATOM   176  N  N   . LEU A 1 21  ? 155.413 119.258 121.435 1.00 69.68  ? 21  LEU B N   1 
ATOM   177  C  CA  . LEU A 1 21  ? 156.760 119.570 120.965 1.00 69.68  ? 21  LEU B CA  1 
ATOM   178  C  C   . LEU A 1 21  ? 157.392 118.434 120.163 1.00 69.68  ? 21  LEU B C   1 
ATOM   179  O  O   . LEU A 1 21  ? 158.046 118.690 119.147 1.00 69.68  ? 21  LEU B O   1 
ATOM   180  C  CB  . LEU A 1 21  ? 157.657 119.939 122.147 1.00 69.68  ? 21  LEU B CB  1 
ATOM   181  C  CG  . LEU A 1 21  ? 157.740 121.422 122.520 1.00 69.68  ? 21  LEU B CG  1 
ATOM   182  C  CD1 . LEU A 1 21  ? 158.362 122.212 121.382 1.00 69.68  ? 21  LEU B CD1 1 
ATOM   183  C  CD2 . LEU A 1 21  ? 156.382 121.994 122.889 1.00 69.68  ? 21  LEU B CD2 1 
ATOM   184  N  N   . VAL A 1 22  ? 157.217 117.181 120.592 1.00 69.01  ? 22  VAL B N   1 
ATOM   185  C  CA  . VAL A 1 22  ? 158.038 116.100 120.054 1.00 69.01  ? 22  VAL B CA  1 
ATOM   186  C  C   . VAL A 1 22  ? 157.710 115.780 118.598 1.00 69.01  ? 22  VAL B C   1 
ATOM   187  O  O   . VAL A 1 22  ? 158.540 115.186 117.899 1.00 69.01  ? 22  VAL B O   1 
ATOM   188  C  CB  . VAL A 1 22  ? 157.907 114.844 120.940 1.00 69.01  ? 22  VAL B CB  1 
ATOM   189  C  CG1 . VAL A 1 22  ? 156.539 114.211 120.787 1.00 69.01  ? 22  VAL B CG1 1 
ATOM   190  C  CG2 . VAL A 1 22  ? 159.014 113.841 120.637 1.00 69.01  ? 22  VAL B CG2 1 
ATOM   191  N  N   . LEU A 1 23  ? 156.536 116.165 118.106 1.00 69.77  ? 23  LEU B N   1 
ATOM   192  C  CA  . LEU A 1 23  ? 156.169 115.883 116.724 1.00 69.77  ? 23  LEU B CA  1 
ATOM   193  C  C   . LEU A 1 23  ? 156.601 116.970 115.749 1.00 69.77  ? 23  LEU B C   1 
ATOM   194  O  O   . LEU A 1 23  ? 156.328 116.842 114.552 1.00 69.77  ? 23  LEU B O   1 
ATOM   195  C  CB  . LEU A 1 23  ? 154.657 115.669 116.597 1.00 69.77  ? 23  LEU B CB  1 
ATOM   196  C  CG  . LEU A 1 23  ? 154.060 114.290 116.885 1.00 69.77  ? 23  LEU B CG  1 
ATOM   197  C  CD1 . LEU A 1 23  ? 153.998 113.996 118.369 1.00 69.77  ? 23  LEU B CD1 1 
ATOM   198  C  CD2 . LEU A 1 23  ? 152.684 114.195 116.268 1.00 69.77  ? 23  LEU B CD2 1 
ATOM   199  N  N   . LEU A 1 24  ? 157.259 118.029 116.222 1.00 75.09  ? 24  LEU B N   1 
ATOM   200  C  CA  . LEU A 1 24  ? 157.737 119.068 115.314 1.00 75.09  ? 24  LEU B CA  1 
ATOM   201  C  C   . LEU A 1 24  ? 158.676 118.571 114.215 1.00 75.09  ? 24  LEU B C   1 
ATOM   202  O  O   . LEU A 1 24  ? 158.706 119.213 113.149 1.00 75.09  ? 24  LEU B O   1 
ATOM   203  C  CB  . LEU A 1 24  ? 158.416 120.189 116.115 1.00 75.09  ? 24  LEU B CB  1 
ATOM   204  C  CG  . LEU A 1 24  ? 157.544 121.382 116.510 1.00 75.09  ? 24  LEU B CG  1 
ATOM   205  C  CD1 . LEU A 1 24  ? 157.080 122.125 115.269 1.00 75.09  ? 24  LEU B CD1 1 
ATOM   206  C  CD2 . LEU A 1 24  ? 156.356 120.948 117.339 1.00 75.09  ? 24  LEU B CD2 1 
ATOM   207  N  N   . PRO A 1 25  ? 159.469 117.504 114.397 1.00 76.72  ? 25  PRO B N   1 
ATOM   208  C  CA  . PRO A 1 25  ? 160.243 116.984 113.259 1.00 76.72  ? 25  PRO B CA  1 
ATOM   209  C  C   . PRO A 1 25  ? 159.411 116.701 112.020 1.00 76.72  ? 25  PRO B C   1 
ATOM   210  O  O   . PRO A 1 25  ? 159.878 116.962 110.906 1.00 76.72  ? 25  PRO B O   1 
ATOM   211  C  CB  . PRO A 1 25  ? 160.863 115.702 113.824 1.00 76.72  ? 25  PRO B CB  1 
ATOM   212  C  CG  . PRO A 1 25  ? 161.013 115.963 115.275 1.00 76.72  ? 25  PRO B CG  1 
ATOM   213  C  CD  . PRO A 1 25  ? 160.021 117.025 115.678 1.00 76.72  ? 25  PRO B CD  1 
ATOM   214  N  N   . LEU A 1 26  ? 158.192 116.184 112.176 1.00 77.33  ? 26  LEU B N   1 
ATOM   215  C  CA  . LEU A 1 26  ? 157.379 115.871 111.002 1.00 77.33  ? 26  LEU B CA  1 
ATOM   216  C  C   . LEU A 1 26  ? 157.109 117.095 110.135 1.00 77.33  ? 26  LEU B C   1 
ATOM   217  O  O   . LEU A 1 26  ? 157.274 116.998 108.907 1.00 77.33  ? 26  LEU B O   1 
ATOM   218  C  CB  . LEU A 1 26  ? 156.082 115.178 111.435 1.00 77.33  ? 26  LEU B CB  1 
ATOM   219  C  CG  . LEU A 1 26  ? 156.046 113.650 111.351 1.00 77.33  ? 26  LEU B CG  1 
ATOM   220  C  CD1 . LEU A 1 26  ? 157.213 113.029 112.106 1.00 77.33  ? 26  LEU B CD1 1 
ATOM   221  C  CD2 . LEU A 1 26  ? 154.723 113.118 111.875 1.00 77.33  ? 26  LEU B CD2 1 
ATOM   222  N  N   . PRO A 1 27  ? 156.702 118.252 110.670 1.00 77.40  ? 27  PRO B N   1 
ATOM   223  C  CA  . PRO A 1 27  ? 156.600 119.429 109.794 1.00 77.40  ? 27  PRO B CA  1 
ATOM   224  C  C   . PRO A 1 27  ? 157.938 120.039 109.409 1.00 77.40  ? 27  PRO B C   1 
ATOM   225  O  O   . PRO A 1 27  ? 158.111 120.416 108.244 1.00 77.40  ? 27  PRO B O   1 
ATOM   226  C  CB  . PRO A 1 27  ? 155.748 120.406 110.618 1.00 77.40  ? 27  PRO B CB  1 
ATOM   227  C  CG  . PRO A 1 27  ? 155.019 119.552 111.581 1.00 77.40  ? 27  PRO B CG  1 
ATOM   228  C  CD  . PRO A 1 27  ? 155.993 118.483 111.939 1.00 77.40  ? 27  PRO B CD  1 
ATOM   229  N  N   . ILE A 1 28  ? 158.893 120.160 110.340 1.00 79.47  ? 28  ILE B N   1 
ATOM   230  C  CA  . ILE A 1 28  ? 160.036 121.034 110.073 1.00 79.47  ? 28  ILE B CA  1 
ATOM   231  C  C   . ILE A 1 28  ? 160.952 120.443 109.003 1.00 79.47  ? 28  ILE B C   1 
ATOM   232  O  O   . ILE A 1 28  ? 161.446 121.168 108.131 1.00 79.47  ? 28  ILE B O   1 
ATOM   233  C  CB  . ILE A 1 28  ? 160.809 121.360 111.366 1.00 79.47  ? 28  ILE B CB  1 
ATOM   234  C  CG1 . ILE A 1 28  ? 161.395 120.103 112.007 1.00 79.47  ? 28  ILE B CG1 1 
ATOM   235  C  CG2 . ILE A 1 28  ? 159.915 122.107 112.347 1.00 79.47  ? 28  ILE B CG2 1 
ATOM   236  C  CD1 . ILE A 1 28  ? 162.352 120.388 113.143 1.00 79.47  ? 28  ILE B CD1 1 
ATOM   237  N  N   . VAL A 1 29  ? 161.198 119.133 109.040 1.00 82.67  ? 29  VAL B N   1 
ATOM   238  C  CA  . VAL A 1 29  ? 162.166 118.539 108.120 1.00 82.67  ? 29  VAL B CA  1 
ATOM   239  C  C   . VAL A 1 29  ? 161.459 118.025 106.872 1.00 82.67  ? 29  VAL B C   1 
ATOM   240  O  O   . VAL A 1 29  ? 162.069 117.357 106.031 1.00 82.67  ? 29  VAL B O   1 
ATOM   241  C  CB  . VAL A 1 29  ? 162.985 117.421 108.795 1.00 82.67  ? 29  VAL B CB  1 
ATOM   242  C  CG1 . VAL A 1 29  ? 163.542 117.895 110.129 1.00 82.67  ? 29  VAL B CG1 1 
ATOM   243  C  CG2 . VAL A 1 29  ? 162.157 116.161 108.969 1.00 82.67  ? 29  VAL B CG2 1 
ATOM   244  N  N   . LEU A 1 30  ? 160.175 118.340 106.738 1.00 81.93  ? 30  LEU B N   1 
ATOM   245  C  CA  . LEU A 1 30  ? 159.421 118.015 105.532 1.00 81.93  ? 30  LEU B CA  1 
ATOM   246  C  C   . LEU A 1 30  ? 158.918 119.240 104.789 1.00 81.93  ? 30  LEU B C   1 
ATOM   247  O  O   . LEU A 1 30  ? 159.052 119.305 103.564 1.00 81.93  ? 30  LEU B O   1 
ATOM   248  C  CB  . LEU A 1 30  ? 158.227 117.109 105.864 1.00 81.93  ? 30  LEU B CB  1 
ATOM   249  C  CG  . LEU A 1 30  ? 158.442 115.593 105.845 1.00 81.93  ? 30  LEU B CG  1 
ATOM   250  C  CD1 . LEU A 1 30  ? 158.853 115.134 104.454 1.00 81.93  ? 30  LEU B CD1 1 
ATOM   251  C  CD2 . LEU A 1 30  ? 159.454 115.145 106.883 1.00 81.93  ? 30  LEU B CD2 1 
ATOM   252  N  N   . HIS A 1 31  ? 158.349 120.217 105.500 1.00 85.15  ? 31  HIS B N   1 
ATOM   253  C  CA  . HIS A 1 31  ? 157.747 121.399 104.880 1.00 85.15  ? 31  HIS B CA  1 
ATOM   254  C  C   . HIS A 1 31  ? 156.726 120.991 103.821 1.00 85.15  ? 31  HIS B C   1 
ATOM   255  O  O   . HIS A 1 31  ? 156.662 121.559 102.729 1.00 85.15  ? 31  HIS B O   1 
ATOM   256  C  CB  . HIS A 1 31  ? 158.816 122.321 104.290 1.00 85.15  ? 31  HIS B CB  1 
ATOM   257  C  CG  . HIS A 1 31  ? 158.331 123.709 104.010 1.00 85.15  ? 31  HIS B CG  1 
ATOM   258  N  ND1 . HIS A 1 31  ? 157.770 124.511 104.980 1.00 85.15  ? 31  HIS B ND1 1 
ATOM   259  C  CD2 . HIS A 1 31  ? 158.324 124.438 102.869 1.00 85.15  ? 31  HIS B CD2 1 
ATOM   260  C  CE1 . HIS A 1 31  ? 157.437 125.674 104.449 1.00 85.15  ? 31  HIS B CE1 1 
ATOM   261  N  NE2 . HIS A 1 31  ? 157.763 125.656 103.169 1.00 85.15  ? 31  HIS B NE2 1 
ATOM   262  N  N   . THR A 1 32  ? 155.923 119.984 104.152 1.00 85.88  ? 32  THR B N   1 
ATOM   263  C  CA  . THR A 1 32  ? 154.962 119.399 103.231 1.00 85.88  ? 32  THR B CA  1 
ATOM   264  C  C   . THR A 1 32  ? 153.584 119.407 103.874 1.00 85.88  ? 32  THR B C   1 
ATOM   265  O  O   . THR A 1 32  ? 153.443 119.090 105.059 1.00 85.88  ? 32  THR B O   1 
ATOM   266  C  CB  . THR A 1 32  ? 155.367 117.966 102.859 1.00 85.88  ? 32  THR B CB  1 
ATOM   267  O  OG1 . THR A 1 32  ? 156.675 117.976 102.274 1.00 85.88  ? 32  THR B OG1 1 
ATOM   268  C  CG2 . THR A 1 32  ? 154.390 117.369 101.867 1.00 85.88  ? 32  THR B CG2 1 
ATOM   269  N  N   . LYS A 1 33  ? 152.569 119.777 103.089 1.00 86.00  ? 33  LYS B N   1 
ATOM   270  C  CA  . LYS A 1 33  ? 151.209 119.828 103.617 1.00 86.00  ? 33  LYS B CA  1 
ATOM   271  C  C   . LYS A 1 33  ? 150.729 118.449 104.048 1.00 86.00  ? 33  LYS B C   1 
ATOM   272  O  O   . LYS A 1 33  ? 149.957 118.324 105.006 1.00 86.00  ? 33  LYS B O   1 
ATOM   273  C  CB  . LYS A 1 33  ? 150.264 120.427 102.578 1.00 86.00  ? 33  LYS B CB  1 
ATOM   274  C  CG  . LYS A 1 33  ? 150.400 121.931 102.420 1.00 86.00  ? 33  LYS B CG  1 
ATOM   275  C  CD  . LYS A 1 33  ? 149.341 122.484 101.485 1.00 86.00  ? 33  LYS B CD  1 
ATOM   276  C  CE  . LYS A 1 33  ? 149.526 123.975 101.268 1.00 86.00  ? 33  LYS B CE  1 
ATOM   277  N  NZ  . LYS A 1 33  ? 149.228 124.750 102.502 1.00 86.00  ? 33  LYS B NZ  1 
ATOM   278  N  N   . GLU A 1 34  ? 151.180 117.399 103.355 1.00 90.70  ? 34  GLU B N   1 
ATOM   279  C  CA  . GLU A 1 34  ? 150.820 116.042 103.750 1.00 90.70  ? 34  GLU B CA  1 
ATOM   280  C  C   . GLU A 1 34  ? 151.295 115.724 105.160 1.00 90.70  ? 34  GLU B C   1 
ATOM   281  O  O   . GLU A 1 34  ? 150.561 115.103 105.936 1.00 90.70  ? 34  GLU B O   1 
ATOM   282  C  CB  . GLU A 1 34  ? 151.397 115.036 102.755 1.00 90.70  ? 34  GLU B CB  1 
ATOM   283  C  CG  . GLU A 1 34  ? 150.745 115.058 101.381 1.00 90.70  ? 34  GLU B CG  1 
ATOM   284  C  CD  . GLU A 1 34  ? 151.337 116.102 100.453 1.00 90.70  ? 34  GLU B CD  1 
ATOM   285  O  OE1 . GLU A 1 34  ? 151.699 115.747 99.311  1.00 90.70  ? 34  GLU B OE1 1 
ATOM   286  O  OE2 . GLU A 1 34  ? 151.415 117.283 100.852 1.00 90.70  ? 34  GLU B OE2 1 
ATOM   287  N  N   . ALA A 1 35  ? 152.510 116.138 105.512 1.00 84.50  ? 35  ALA B N   1 
ATOM   288  C  CA  . ALA A 1 35  ? 153.011 115.941 106.865 1.00 84.50  ? 35  ALA B CA  1 
ATOM   289  C  C   . ALA A 1 35  ? 152.418 116.930 107.856 1.00 84.50  ? 35  ALA B C   1 
ATOM   290  O  O   . ALA A 1 35  ? 152.217 116.581 109.024 1.00 84.50  ? 35  ALA B O   1 
ATOM   291  C  CB  . ALA A 1 35  ? 154.537 116.049 106.886 1.00 84.50  ? 35  ALA B CB  1 
ATOM   292  N  N   . GLU A 1 36  ? 152.130 118.156 107.415 1.00 84.03  ? 36  GLU B N   1 
ATOM   293  C  CA  . GLU A 1 36  ? 151.576 119.156 108.321 1.00 84.03  ? 36  GLU B CA  1 
ATOM   294  C  C   . GLU A 1 36  ? 150.149 118.819 108.733 1.00 84.03  ? 36  GLU B C   1 
ATOM   295  O  O   . GLU A 1 36  ? 149.738 119.147 109.851 1.00 84.03  ? 36  GLU B O   1 
ATOM   296  C  CB  . GLU A 1 36  ? 151.645 120.539 107.674 1.00 84.03  ? 36  GLU B CB  1 
ATOM   297  C  CG  . GLU A 1 36  ? 153.054 121.114 107.628 1.00 84.03  ? 36  GLU B CG  1 
ATOM   298  C  CD  . GLU A 1 36  ? 153.203 122.232 106.617 1.00 84.03  ? 36  GLU B CD  1 
ATOM   299  O  OE1 . GLU A 1 36  ? 152.226 122.977 106.400 1.00 84.03  ? 36  GLU B OE1 1 
ATOM   300  O  OE2 . GLU A 1 36  ? 154.302 122.368 106.040 1.00 84.03  ? 36  GLU B OE2 1 
ATOM   301  N  N   . CYS A 1 37  ? 149.378 118.175 107.854 1.00 80.68  ? 37  CYS B N   1 
ATOM   302  C  CA  . CYS A 1 37  ? 148.048 117.721 108.249 1.00 80.68  ? 37  CYS B CA  1 
ATOM   303  C  C   . CYS A 1 37  ? 148.134 116.505 109.164 1.00 80.68  ? 37  CYS B C   1 
ATOM   304  O  O   . CYS A 1 37  ? 147.348 116.374 110.112 1.00 80.68  ? 37  CYS B O   1 
ATOM   305  C  CB  . CYS A 1 37  ? 147.211 117.407 107.011 1.00 80.68  ? 37  CYS B CB  1 
ATOM   306  S  SG  . CYS A 1 37  ? 145.444 117.235 107.335 1.00 80.68  ? 37  CYS B SG  1 
ATOM   307  N  N   . ALA A 1 38  ? 149.084 115.606 108.895 1.00 78.26  ? 38  ALA B N   1 
ATOM   308  C  CA  . ALA A 1 38  ? 149.271 114.440 109.750 1.00 78.26  ? 38  ALA B CA  1 
ATOM   309  C  C   . ALA A 1 38  ? 149.723 114.835 111.148 1.00 78.26  ? 38  ALA B C   1 
ATOM   310  O  O   . ALA A 1 38  ? 149.362 114.170 112.123 1.00 78.26  ? 38  ALA B O   1 
ATOM   311  C  CB  . ALA A 1 38  ? 150.277 113.479 109.119 1.00 78.26  ? 38  ALA B CB  1 
ATOM   312  N  N   . TYR A 1 39  ? 150.512 115.903 111.263 1.00 71.20  ? 39  TYR B N   1 
ATOM   313  C  CA  . TYR A 1 39  ? 150.910 116.400 112.576 1.00 71.20  ? 39  TYR B CA  1 
ATOM   314  C  C   . TYR A 1 39  ? 149.691 116.785 113.407 1.00 71.20  ? 39  TYR B C   1 
ATOM   315  O  O   . TYR A 1 39  ? 149.550 116.366 114.565 1.00 71.20  ? 39  TYR B O   1 
ATOM   316  C  CB  . TYR A 1 39  ? 151.851 117.592 112.403 1.00 71.20  ? 39  TYR B CB  1 
ATOM   317  C  CG  . TYR A 1 39  ? 152.090 118.403 113.654 1.00 71.20  ? 39  TYR B CG  1 
ATOM   318  C  CD1 . TYR A 1 39  ? 152.933 117.942 114.651 1.00 71.20  ? 39  TYR B CD1 1 
ATOM   319  C  CD2 . TYR A 1 39  ? 151.479 119.634 113.833 1.00 71.20  ? 39  TYR B CD2 1 
ATOM   320  C  CE1 . TYR A 1 39  ? 153.159 118.682 115.793 1.00 71.20  ? 39  TYR B CE1 1 
ATOM   321  C  CE2 . TYR A 1 39  ? 151.698 120.380 114.972 1.00 71.20  ? 39  TYR B CE2 1 
ATOM   322  C  CZ  . TYR A 1 39  ? 152.539 119.899 115.949 1.00 71.20  ? 39  TYR B CZ  1 
ATOM   323  O  OH  . TYR A 1 39  ? 152.763 120.636 117.088 1.00 71.20  ? 39  TYR B OH  1 
ATOM   324  N  N   . THR A 1 40  ? 148.788 117.574 112.820 1.00 68.90  ? 40  THR B N   1 
ATOM   325  C  CA  . THR A 1 40  ? 147.570 117.966 113.520 1.00 68.90  ? 40  THR B CA  1 
ATOM   326  C  C   . THR A 1 40  ? 146.705 116.758 113.843 1.00 68.90  ? 40  THR B C   1 
ATOM   327  O  O   . THR A 1 40  ? 146.145 116.662 114.943 1.00 68.90  ? 40  THR B O   1 
ATOM   328  C  CB  . THR A 1 40  ? 146.781 118.971 112.683 1.00 68.90  ? 40  THR B CB  1 
ATOM   329  O  OG1 . THR A 1 40  ? 147.618 120.086 112.357 1.00 68.90  ? 40  THR B OG1 1 
ATOM   330  C  CG2 . THR A 1 40  ? 145.562 119.455 113.445 1.00 68.90  ? 40  THR B CG2 1 
ATOM   331  N  N   . LEU A 1 41  ? 146.576 115.827 112.895 1.00 65.92  ? 41  LEU B N   1 
ATOM   332  C  CA  . LEU A 1 41  ? 145.769 114.637 113.139 1.00 65.92  ? 41  LEU B CA  1 
ATOM   333  C  C   . LEU A 1 41  ? 146.316 113.841 114.317 1.00 65.92  ? 41  LEU B C   1 
ATOM   334  O  O   . LEU A 1 41  ? 145.561 113.420 115.200 1.00 65.92  ? 41  LEU B O   1 
ATOM   335  C  CB  . LEU A 1 41  ? 145.714 113.774 111.878 1.00 65.92  ? 41  LEU B CB  1 
ATOM   336  C  CG  . LEU A 1 41  ? 144.834 112.523 111.924 1.00 65.92  ? 41  LEU B CG  1 
ATOM   337  C  CD1 . LEU A 1 41  ? 144.109 112.340 110.606 1.00 65.92  ? 41  LEU B CD1 1 
ATOM   338  C  CD2 . LEU A 1 41  ? 145.662 111.290 112.236 1.00 65.92  ? 41  LEU B CD2 1 
ATOM   339  N  N   . PHE A 1 42  ? 147.635 113.642 114.354 1.00 63.44  ? 42  PHE B N   1 
ATOM   340  C  CA  . PHE A 1 42  ? 148.243 112.876 115.435 1.00 63.44  ? 42  PHE B CA  1 
ATOM   341  C  C   . PHE A 1 42  ? 148.073 113.579 116.774 1.00 63.44  ? 42  PHE B C   1 
ATOM   342  O  O   . PHE A 1 42  ? 147.746 112.939 117.779 1.00 63.44  ? 42  PHE B O   1 
ATOM   343  C  CB  . PHE A 1 42  ? 149.724 112.642 115.143 1.00 63.44  ? 42  PHE B CB  1 
ATOM   344  C  CG  . PHE A 1 42  ? 149.994 111.478 114.230 1.00 63.44  ? 42  PHE B CG  1 
ATOM   345  C  CD1 . PHE A 1 42  ? 149.047 111.058 113.314 1.00 63.44  ? 42  PHE B CD1 1 
ATOM   346  C  CD2 . PHE A 1 42  ? 151.206 110.813 114.282 1.00 63.44  ? 42  PHE B CD2 1 
ATOM   347  C  CE1 . PHE A 1 42  ? 149.299 109.993 112.474 1.00 63.44  ? 42  PHE B CE1 1 
ATOM   348  C  CE2 . PHE A 1 42  ? 151.465 109.747 113.445 1.00 63.44  ? 42  PHE B CE2 1 
ATOM   349  C  CZ  . PHE A 1 42  ? 150.510 109.337 112.540 1.00 63.44  ? 42  PHE B CZ  1 
ATOM   350  N  N   . VAL A 1 43  ? 148.286 114.898 116.808 1.00 60.01  ? 43  VAL B N   1 
ATOM   351  C  CA  . VAL A 1 43  ? 148.165 115.632 118.067 1.00 60.01  ? 43  VAL B CA  1 
ATOM   352  C  C   . VAL A 1 43  ? 146.735 115.563 118.591 1.00 60.01  ? 43  VAL B C   1 
ATOM   353  O  O   . VAL A 1 43  ? 146.498 115.282 119.775 1.00 60.01  ? 43  VAL B O   1 
ATOM   354  C  CB  . VAL A 1 43  ? 148.632 117.087 117.887 1.00 60.01  ? 43  VAL B CB  1 
ATOM   355  C  CG1 . VAL A 1 43  ? 148.193 117.932 119.063 1.00 60.01  ? 43  VAL B CG1 1 
ATOM   356  C  CG2 . VAL A 1 43  ? 150.139 117.137 117.739 1.00 60.01  ? 43  VAL B CG2 1 
ATOM   357  N  N   . VAL A 1 44  ? 145.758 115.809 117.715 1.00 57.11  ? 44  VAL B N   1 
ATOM   358  C  CA  . VAL A 1 44  ? 144.364 115.793 118.141 1.00 57.11  ? 44  VAL B CA  1 
ATOM   359  C  C   . VAL A 1 44  ? 143.952 114.395 118.582 1.00 57.11  ? 44  VAL B C   1 
ATOM   360  O  O   . VAL A 1 44  ? 143.248 114.232 119.586 1.00 57.11  ? 44  VAL B O   1 
ATOM   361  C  CB  . VAL A 1 44  ? 143.458 116.332 117.020 1.00 57.11  ? 44  VAL B CB  1 
ATOM   362  C  CG1 . VAL A 1 44  ? 141.998 116.139 117.378 1.00 57.11  ? 44  VAL B CG1 1 
ATOM   363  C  CG2 . VAL A 1 44  ? 143.749 117.800 116.774 1.00 57.11  ? 44  VAL B CG2 1 
ATOM   364  N  N   . ALA A 1 45  ? 144.382 113.364 117.850 1.00 54.51  ? 45  ALA B N   1 
ATOM   365  C  CA  . ALA A 1 45  ? 144.040 111.999 118.233 1.00 54.51  ? 45  ALA B CA  1 
ATOM   366  C  C   . ALA A 1 45  ? 144.643 111.633 119.583 1.00 54.51  ? 45  ALA B C   1 
ATOM   367  O  O   . ALA A 1 45  ? 143.983 110.995 120.412 1.00 54.51  ? 45  ALA B O   1 
ATOM   368  C  CB  . ALA A 1 45  ? 144.503 111.021 117.155 1.00 54.51  ? 45  ALA B CB  1 
ATOM   369  N  N   . THR A 1 46  ? 145.898 112.021 119.822 1.00 53.33  ? 46  THR B N   1 
ATOM   370  C  CA  . THR A 1 46  ? 146.523 111.726 121.106 1.00 53.33  ? 46  THR B CA  1 
ATOM   371  C  C   . THR A 1 46  ? 145.795 112.426 122.244 1.00 53.33  ? 46  THR B C   1 
ATOM   372  O  O   . THR A 1 46  ? 145.543 111.823 123.295 1.00 53.33  ? 46  THR B O   1 
ATOM   373  C  CB  . THR A 1 46  ? 147.995 112.134 121.082 1.00 53.33  ? 46  THR B CB  1 
ATOM   374  O  OG1 . THR A 1 46  ? 148.690 111.357 120.101 1.00 53.33  ? 46  THR B OG1 1 
ATOM   375  C  CG2 . THR A 1 46  ? 148.631 111.907 122.441 1.00 53.33  ? 46  THR B CG2 1 
ATOM   376  N  N   . PHE A 1 47  ? 145.436 113.698 122.050 1.00 51.74  ? 47  PHE B N   1 
ATOM   377  C  CA  . PHE A 1 47  ? 144.717 114.412 123.099 1.00 51.74  ? 47  PHE B CA  1 
ATOM   378  C  C   . PHE A 1 47  ? 143.334 113.819 123.339 1.00 51.74  ? 47  PHE B C   1 
ATOM   379  O  O   . PHE A 1 47  ? 142.866 113.789 124.482 1.00 51.74  ? 47  PHE B O   1 
ATOM   380  C  CB  . PHE A 1 47  ? 144.608 115.895 122.753 1.00 51.74  ? 47  PHE B CB  1 
ATOM   381  C  CG  . PHE A 1 47  ? 145.897 116.647 122.899 1.00 51.74  ? 47  PHE B CG  1 
ATOM   382  C  CD1 . PHE A 1 47  ? 146.965 116.090 123.578 1.00 51.74  ? 47  PHE B CD1 1 
ATOM   383  C  CD2 . PHE A 1 47  ? 146.039 117.912 122.362 1.00 51.74  ? 47  PHE B CD2 1 
ATOM   384  C  CE1 . PHE A 1 47  ? 148.149 116.778 123.713 1.00 51.74  ? 47  PHE B CE1 1 
ATOM   385  C  CE2 . PHE A 1 47  ? 147.222 118.605 122.495 1.00 51.74  ? 47  PHE B CE2 1 
ATOM   386  C  CZ  . PHE A 1 47  ? 148.278 118.037 123.171 1.00 51.74  ? 47  PHE B CZ  1 
ATOM   387  N  N   . TRP A 1 48  ? 142.665 113.352 122.282 1.00 51.57  ? 48  TRP B N   1 
ATOM   388  C  CA  . TRP A 1 48  ? 141.357 112.726 122.450 1.00 51.57  ? 48  TRP B CA  1 
ATOM   389  C  C   . TRP A 1 48  ? 141.465 111.414 123.214 1.00 51.57  ? 48  TRP B C   1 
ATOM   390  O  O   . TRP A 1 48  ? 140.693 111.161 124.145 1.00 51.57  ? 48  TRP B O   1 
ATOM   391  C  CB  . TRP A 1 48  ? 140.707 112.495 121.086 1.00 51.57  ? 48  TRP B CB  1 
ATOM   392  C  CG  . TRP A 1 48  ? 139.845 113.619 120.625 1.00 51.57  ? 48  TRP B CG  1 
ATOM   393  C  CD1 . TRP A 1 48  ? 139.296 114.599 121.394 1.00 51.57  ? 48  TRP B CD1 1 
ATOM   394  C  CD2 . TRP A 1 48  ? 139.425 113.880 119.282 1.00 51.57  ? 48  TRP B CD2 1 
ATOM   395  N  NE1 . TRP A 1 48  ? 138.560 115.456 120.615 1.00 51.57  ? 48  TRP B NE1 1 
ATOM   396  C  CE2 . TRP A 1 48  ? 138.625 115.037 119.313 1.00 51.57  ? 48  TRP B CE2 1 
ATOM   397  C  CE3 . TRP A 1 48  ? 139.650 113.249 118.057 1.00 51.57  ? 48  TRP B CE3 1 
ATOM   398  C  CZ2 . TRP A 1 48  ? 138.049 115.576 118.167 1.00 51.57  ? 48  TRP B CZ2 1 
ATOM   399  C  CZ3 . TRP A 1 48  ? 139.077 113.785 116.920 1.00 51.57  ? 48  TRP B CZ3 1 
ATOM   400  C  CH2 . TRP A 1 48  ? 138.286 114.936 116.983 1.00 51.57  ? 48  TRP B CH2 1 
ATOM   401  N  N   . LEU A 1 49  ? 142.420 110.563 122.834 1.00 49.87  ? 49  LEU B N   1 
ATOM   402  C  CA  . LEU A 1 49  ? 142.509 109.239 123.437 1.00 49.87  ? 49  LEU B CA  1 
ATOM   403  C  C   . LEU A 1 49  ? 143.073 109.269 124.851 1.00 49.87  ? 49  LEU B C   1 
ATOM   404  O  O   . LEU A 1 49  ? 142.686 108.432 125.671 1.00 49.87  ? 49  LEU B O   1 
ATOM   405  C  CB  . LEU A 1 49  ? 143.356 108.317 122.560 1.00 49.87  ? 49  LEU B CB  1 
ATOM   406  C  CG  . LEU A 1 49  ? 142.850 108.118 121.132 1.00 49.87  ? 49  LEU B CG  1 
ATOM   407  C  CD1 . LEU A 1 49  ? 143.954 107.575 120.243 1.00 49.87  ? 49  LEU B CD1 1 
ATOM   408  C  CD2 . LEU A 1 49  ? 141.642 107.200 121.116 1.00 49.87  ? 49  LEU B CD2 1 
ATOM   409  N  N   . THR A 1 50  ? 143.968 110.206 125.161 1.00 51.78  ? 50  THR B N   1 
ATOM   410  C  CA  . THR A 1 50  ? 144.568 110.255 126.486 1.00 51.78  ? 50  THR B CA  1 
ATOM   411  C  C   . THR A 1 50  ? 143.796 111.136 127.459 1.00 51.78  ? 50  THR B C   1 
ATOM   412  O  O   . THR A 1 50  ? 143.994 111.013 128.673 1.00 51.78  ? 50  THR B O   1 
ATOM   413  C  CB  . THR A 1 50  ? 146.017 110.747 126.390 1.00 51.78  ? 50  THR B CB  1 
ATOM   414  O  OG1 . THR A 1 50  ? 146.673 110.076 125.309 1.00 51.78  ? 50  THR B OG1 1 
ATOM   415  C  CG2 . THR A 1 50  ? 146.774 110.435 127.670 1.00 51.78  ? 50  THR B CG2 1 
ATOM   416  N  N   . GLU A 1 51  ? 142.910 111.998 126.959 1.00 56.69  ? 51  GLU B N   1 
ATOM   417  C  CA  . GLU A 1 51  ? 142.135 112.924 127.784 1.00 56.69  ? 51  GLU B CA  1 
ATOM   418  C  C   . GLU A 1 51  ? 143.066 113.837 128.587 1.00 56.69  ? 51  GLU B C   1 
ATOM   419  O  O   . GLU A 1 51  ? 142.971 113.964 129.809 1.00 56.69  ? 51  GLU B O   1 
ATOM   420  C  CB  . GLU A 1 51  ? 141.162 112.165 128.697 1.00 56.69  ? 51  GLU B CB  1 
ATOM   421  C  CG  . GLU A 1 51  ? 140.130 113.037 129.400 1.00 56.69  ? 51  GLU B CG  1 
ATOM   422  C  CD  . GLU A 1 51  ? 138.945 113.363 128.519 1.00 56.69  ? 51  GLU B CD  1 
ATOM   423  O  OE1 . GLU A 1 51  ? 138.886 112.839 127.388 1.00 56.69  ? 51  GLU B OE1 1 
ATOM   424  O  OE2 . GLU A 1 51  ? 138.072 114.140 128.958 1.00 56.69  ? 51  GLU B OE2 1 
ATOM   425  N  N   . ALA A 1 52  ? 143.997 114.461 127.866 1.00 56.74  ? 52  ALA B N   1 
ATOM   426  C  CA  . ALA A 1 52  ? 144.864 115.459 128.480 1.00 56.74  ? 52  ALA B CA  1 
ATOM   427  C  C   . ALA A 1 52  ? 144.125 116.781 128.651 1.00 56.74  ? 52  ALA B C   1 
ATOM   428  O  O   . ALA A 1 52  ? 144.210 117.425 129.700 1.00 56.74  ? 52  ALA B O   1 
ATOM   429  C  CB  . ALA A 1 52  ? 146.129 115.642 127.642 1.00 56.74  ? 52  ALA B CB  1 
ATOM   430  N  N   . LEU A 1 53  ? 143.400 117.194 127.633 1.00 54.86  ? 53  LEU B N   1 
ATOM   431  C  CA  . LEU A 1 53  ? 142.503 118.334 127.688 1.00 54.86  ? 53  LEU B CA  1 
ATOM   432  C  C   . LEU A 1 53  ? 141.067 117.875 127.493 1.00 54.86  ? 53  LEU B C   1 
ATOM   433  O  O   . LEU A 1 53  ? 140.822 116.781 126.976 1.00 54.86  ? 53  LEU B O   1 
ATOM   434  C  CB  . LEU A 1 53  ? 142.875 119.362 126.614 1.00 54.86  ? 53  LEU B CB  1 
ATOM   435  C  CG  . LEU A 1 53  ? 144.361 119.675 126.447 1.00 54.86  ? 53  LEU B CG  1 
ATOM   436  C  CD1 . LEU A 1 53  ? 144.571 120.667 125.318 1.00 54.86  ? 53  LEU B CD1 1 
ATOM   437  C  CD2 . LEU A 1 53  ? 144.937 120.209 127.743 1.00 54.86  ? 53  LEU B CD2 1 
ATOM   438  N  N   . PRO A 1 54  ? 140.086 118.675 127.911 1.00 57.26  ? 54  PRO B N   1 
ATOM   439  C  CA  . PRO A 1 54  ? 138.689 118.306 127.662 1.00 57.26  ? 54  PRO B CA  1 
ATOM   440  C  C   . PRO A 1 54  ? 138.430 118.119 126.175 1.00 57.26  ? 54  PRO B C   1 
ATOM   441  O  O   . PRO A 1 54  ? 139.065 118.747 125.326 1.00 57.26  ? 54  PRO B O   1 
ATOM   442  C  CB  . PRO A 1 54  ? 137.901 119.492 128.226 1.00 57.26  ? 54  PRO B CB  1 
ATOM   443  C  CG  . PRO A 1 54  ? 138.791 120.063 129.269 1.00 57.26  ? 54  PRO B CG  1 
ATOM   444  C  CD  . PRO A 1 54  ? 140.195 119.867 128.771 1.00 57.26  ? 54  PRO B CD  1 
ATOM   445  N  N   . LEU A 1 55  ? 137.491 117.221 125.868 1.00 56.48  ? 55  LEU B N   1 
ATOM   446  C  CA  . LEU A 1 55  ? 137.295 116.787 124.489 1.00 56.48  ? 55  LEU B CA  1 
ATOM   447  C  C   . LEU A 1 55  ? 136.929 117.951 123.576 1.00 56.48  ? 55  LEU B C   1 
ATOM   448  O  O   . LEU A 1 55  ? 137.392 118.018 122.433 1.00 56.48  ? 55  LEU B O   1 
ATOM   449  C  CB  . LEU A 1 55  ? 136.223 115.701 124.435 1.00 56.48  ? 55  LEU B CB  1 
ATOM   450  C  CG  . LEU A 1 55  ? 136.612 114.385 125.107 1.00 56.48  ? 55  LEU B CG  1 
ATOM   451  C  CD1 . LEU A 1 55  ? 135.503 113.359 124.964 1.00 56.48  ? 55  LEU B CD1 1 
ATOM   452  C  CD2 . LEU A 1 55  ? 137.908 113.865 124.515 1.00 56.48  ? 55  LEU B CD2 1 
ATOM   453  N  N   . SER A 1 56  ? 136.094 118.874 124.055 1.00 56.05  ? 56  SER B N   1 
ATOM   454  C  CA  . SER A 1 56  ? 135.768 120.048 123.252 1.00 56.05  ? 56  SER B CA  1 
ATOM   455  C  C   . SER A 1 56  ? 136.987 120.942 123.062 1.00 56.05  ? 56  SER B C   1 
ATOM   456  O  O   . SER A 1 56  ? 137.185 121.516 121.983 1.00 56.05  ? 56  SER B O   1 
ATOM   457  C  CB  . SER A 1 56  ? 134.625 120.822 123.901 1.00 56.05  ? 56  SER B CB  1 
ATOM   458  O  OG  . SER A 1 56  ? 133.561 119.953 124.238 1.00 56.05  ? 56  SER B OG  1 
ATOM   459  N  N   . VAL A 1 57  ? 137.817 121.068 124.099 1.00 55.03  ? 57  VAL B N   1 
ATOM   460  C  CA  . VAL A 1 57  ? 139.043 121.853 123.985 1.00 55.03  ? 57  VAL B CA  1 
ATOM   461  C  C   . VAL A 1 57  ? 139.942 121.277 122.900 1.00 55.03  ? 57  VAL B C   1 
ATOM   462  O  O   . VAL A 1 57  ? 140.502 122.014 122.079 1.00 55.03  ? 57  VAL B O   1 
ATOM   463  C  CB  . VAL A 1 57  ? 139.761 121.915 125.344 1.00 55.03  ? 57  VAL B CB  1 
ATOM   464  C  CG1 . VAL A 1 57  ? 141.039 122.721 125.237 1.00 55.03  ? 57  VAL B CG1 1 
ATOM   465  C  CG2 . VAL A 1 57  ? 138.842 122.505 126.396 1.00 55.03  ? 57  VAL B CG2 1 
ATOM   466  N  N   . THR A 1 58  ? 140.095 119.952 122.877 1.00 55.44  ? 58  THR B N   1 
ATOM   467  C  CA  . THR A 1 58  ? 140.878 119.318 121.822 1.00 55.44  ? 58  THR B CA  1 
ATOM   468  C  C   . THR A 1 58  ? 140.227 119.511 120.459 1.00 55.44  ? 58  THR B C   1 
ATOM   469  O  O   . THR A 1 58  ? 140.914 119.784 119.468 1.00 55.44  ? 58  THR B O   1 
ATOM   470  C  CB  . THR A 1 58  ? 141.057 117.832 122.124 1.00 55.44  ? 58  THR B CB  1 
ATOM   471  O  OG1 . THR A 1 58  ? 141.817 117.675 123.328 1.00 55.44  ? 58  THR B OG1 1 
ATOM   472  C  CG2 . THR A 1 58  ? 141.777 117.141 120.981 1.00 55.44  ? 58  THR B CG2 1 
ATOM   473  N  N   . ALA A 1 59  ? 138.900 119.381 120.389 1.00 57.00  ? 59  ALA B N   1 
ATOM   474  C  CA  . ALA A 1 59  ? 138.207 119.524 119.114 1.00 57.00  ? 59  ALA B CA  1 
ATOM   475  C  C   . ALA A 1 59  ? 138.341 120.934 118.559 1.00 57.00  ? 59  ALA B C   1 
ATOM   476  O  O   . ALA A 1 59  ? 138.215 121.140 117.347 1.00 57.00  ? 59  ALA B O   1 
ATOM   477  C  CB  . ALA A 1 59  ? 136.734 119.153 119.272 1.00 57.00  ? 59  ALA B CB  1 
ATOM   478  N  N   . LEU A 1 60  ? 138.574 121.917 119.427 1.00 58.99  ? 60  LEU B N   1 
ATOM   479  C  CA  . LEU A 1 60  ? 138.808 123.274 118.951 1.00 58.99  ? 60  LEU B CA  1 
ATOM   480  C  C   . LEU A 1 60  ? 140.175 123.436 118.294 1.00 58.99  ? 60  LEU B C   1 
ATOM   481  O  O   . LEU A 1 60  ? 140.375 124.397 117.545 1.00 58.99  ? 60  LEU B O   1 
ATOM   482  C  CB  . LEU A 1 60  ? 138.666 124.268 120.102 1.00 58.99  ? 60  LEU B CB  1 
ATOM   483  C  CG  . LEU A 1 60  ? 137.238 124.511 120.588 1.00 58.99  ? 60  LEU B CG  1 
ATOM   484  C  CD1 . LEU A 1 60  ? 137.241 125.096 121.988 1.00 58.99  ? 60  LEU B CD1 1 
ATOM   485  C  CD2 . LEU A 1 60  ? 136.504 125.424 119.625 1.00 58.99  ? 60  LEU B CD2 1 
ATOM   486  N  N   . LEU A 1 61  ? 141.113 122.524 118.558 1.00 64.12  ? 61  LEU B N   1 
ATOM   487  C  CA  . LEU A 1 61  ? 142.467 122.663 118.022 1.00 64.12  ? 61  LEU B CA  1 
ATOM   488  C  C   . LEU A 1 61  ? 142.534 122.656 116.498 1.00 64.12  ? 61  LEU B C   1 
ATOM   489  O  O   . LEU A 1 61  ? 143.255 123.498 115.937 1.00 64.12  ? 61  LEU B O   1 
ATOM   490  C  CB  . LEU A 1 61  ? 143.372 121.579 118.619 1.00 64.12  ? 61  LEU B CB  1 
ATOM   491  C  CG  . LEU A 1 61  ? 143.758 121.756 120.087 1.00 64.12  ? 61  LEU B CG  1 
ATOM   492  C  CD1 . LEU A 1 61  ? 145.025 120.982 120.401 1.00 64.12  ? 61  LEU B CD1 1 
ATOM   493  C  CD2 . LEU A 1 61  ? 143.935 123.227 120.418 1.00 64.12  ? 61  LEU B CD2 1 
ATOM   494  N  N   . PRO A 1 62  ? 141.852 121.761 115.772 1.00 67.81  ? 62  PRO B N   1 
ATOM   495  C  CA  . PRO A 1 62  ? 141.979 121.778 114.304 1.00 67.81  ? 62  PRO B CA  1 
ATOM   496  C  C   . PRO A 1 62  ? 141.531 123.077 113.662 1.00 67.81  ? 62  PRO B C   1 
ATOM   497  O  O   . PRO A 1 62  ? 141.904 123.340 112.514 1.00 67.81  ? 62  PRO B O   1 
ATOM   498  C  CB  . PRO A 1 62  ? 141.097 120.606 113.860 1.00 67.81  ? 62  PRO B CB  1 
ATOM   499  C  CG  . PRO A 1 62  ? 141.079 119.697 115.019 1.00 67.81  ? 62  PRO B CG  1 
ATOM   500  C  CD  . PRO A 1 62  ? 141.089 120.584 116.224 1.00 67.81  ? 62  PRO B CD  1 
ATOM   501  N  N   . SER A 1 63  ? 140.735 123.893 114.350 1.00 67.70  ? 63  SER B N   1 
ATOM   502  C  CA  . SER A 1 63  ? 140.359 125.188 113.802 1.00 67.70  ? 63  SER B CA  1 
ATOM   503  C  C   . SER A 1 63  ? 141.462 126.228 113.943 1.00 67.70  ? 63  SER B C   1 
ATOM   504  O  O   . SER A 1 63  ? 141.421 127.250 113.250 1.00 67.70  ? 63  SER B O   1 
ATOM   505  C  CB  . SER A 1 63  ? 139.085 125.697 114.478 1.00 67.70  ? 63  SER B CB  1 
ATOM   506  O  OG  . SER A 1 63  ? 137.990 124.841 114.208 1.00 67.70  ? 63  SER B OG  1 
ATOM   507  N  N   . LEU A 1 64  ? 142.445 125.989 114.810 1.00 68.70  ? 64  LEU B N   1 
ATOM   508  C  CA  . LEU A 1 64  ? 143.493 126.962 115.092 1.00 68.70  ? 64  LEU B CA  1 
ATOM   509  C  C   . LEU A 1 64  ? 144.827 126.587 114.464 1.00 68.70  ? 64  LEU B C   1 
ATOM   510  O  O   . LEU A 1 64  ? 145.402 127.381 113.716 1.00 68.70  ? 64  LEU B O   1 
ATOM   511  C  CB  . LEU A 1 64  ? 143.662 127.122 116.605 1.00 68.70  ? 64  LEU B CB  1 
ATOM   512  C  CG  . LEU A 1 64  ? 142.353 127.293 117.361 1.00 68.70  ? 64  LEU B CG  1 
ATOM   513  C  CD1 . LEU A 1 64  ? 142.575 127.090 118.846 1.00 68.70  ? 64  LEU B CD1 1 
ATOM   514  C  CD2 . LEU A 1 64  ? 141.813 128.675 117.067 1.00 68.70  ? 64  LEU B CD2 1 
ATOM   515  N  N   . MET A 1 65  ? 145.343 125.396 114.764 1.00 75.39  ? 65  MET B N   1 
ATOM   516  C  CA  . MET A 1 65  ? 146.680 125.034 114.314 1.00 75.39  ? 65  MET B CA  1 
ATOM   517  C  C   . MET A 1 65  ? 146.712 124.661 112.838 1.00 75.39  ? 65  MET B C   1 
ATOM   518  O  O   . MET A 1 65  ? 147.758 124.797 112.195 1.00 75.39  ? 65  MET B O   1 
ATOM   519  C  CB  . MET A 1 65  ? 147.223 123.895 115.177 1.00 75.39  ? 65  MET B CB  1 
ATOM   520  C  CG  . MET A 1 65  ? 146.539 122.563 114.964 1.00 75.39  ? 65  MET B CG  1 
ATOM   521  S  SD  . MET A 1 65  ? 146.840 121.423 116.326 1.00 75.39  ? 65  MET B SD  1 
ATOM   522  C  CE  . MET A 1 65  ? 148.628 121.432 116.391 1.00 75.39  ? 65  MET B CE  1 
ATOM   523  N  N   . LEU A 1 66  ? 145.596 124.189 112.288 1.00 76.09  ? 66  LEU B N   1 
ATOM   524  C  CA  . LEU A 1 66  ? 145.553 123.878 110.861 1.00 76.09  ? 66  LEU B CA  1 
ATOM   525  C  C   . LEU A 1 66  ? 145.746 125.109 109.981 1.00 76.09  ? 66  LEU B C   1 
ATOM   526  O  O   . LEU A 1 66  ? 146.563 125.044 109.046 1.00 76.09  ? 66  LEU B O   1 
ATOM   527  C  CB  . LEU A 1 66  ? 144.248 123.145 110.535 1.00 76.09  ? 66  LEU B CB  1 
ATOM   528  C  CG  . LEU A 1 66  ? 144.175 122.358 109.229 1.00 76.09  ? 66  LEU B CG  1 
ATOM   529  C  CD1 . LEU A 1 66  ? 145.115 121.167 109.275 1.00 76.09  ? 66  LEU B CD1 1 
ATOM   530  C  CD2 . LEU A 1 66  ? 142.748 121.908 108.969 1.00 76.09  ? 66  LEU B CD2 1 
ATOM   531  N  N   . PRO A 1 67  ? 145.054 126.236 110.197 1.00 77.08  ? 67  PRO B N   1 
ATOM   532  C  CA  . PRO A 1 67  ? 145.307 127.413 109.348 1.00 77.08  ? 67  PRO B CA  1 
ATOM   533  C  C   . PRO A 1 67  ? 146.725 127.950 109.434 1.00 77.08  ? 67  PRO B C   1 
ATOM   534  O  O   . PRO A 1 67  ? 147.174 128.610 108.489 1.00 77.08  ? 67  PRO B O   1 
ATOM   535  C  CB  . PRO A 1 67  ? 144.288 128.442 109.858 1.00 77.08  ? 67  PRO B CB  1 
ATOM   536  C  CG  . PRO A 1 67  ? 143.219 127.631 110.478 1.00 77.08  ? 67  PRO B CG  1 
ATOM   537  C  CD  . PRO A 1 67  ? 143.923 126.476 111.111 1.00 77.08  ? 67  PRO B CD  1 
ATOM   538  N  N   . MET A 1 68  ? 147.446 127.700 110.529 1.00 76.59  ? 68  MET B N   1 
ATOM   539  C  CA  . MET A 1 68  ? 148.827 128.156 110.620 1.00 76.59  ? 68  MET B CA  1 
ATOM   540  C  C   . MET A 1 68  ? 149.726 127.483 109.593 1.00 76.59  ? 68  MET B C   1 
ATOM   541  O  O   . MET A 1 68  ? 150.754 128.055 109.218 1.00 76.59  ? 68  MET B O   1 
ATOM   542  C  CB  . MET A 1 68  ? 149.379 127.909 112.023 1.00 76.59  ? 68  MET B CB  1 
ATOM   543  C  CG  . MET A 1 68  ? 148.384 128.165 113.135 1.00 76.59  ? 68  MET B CG  1 
ATOM   544  S  SD  . MET A 1 68  ? 148.315 129.894 113.629 1.00 76.59  ? 68  MET B SD  1 
ATOM   545  C  CE  . MET A 1 68  ? 150.045 130.229 113.935 1.00 76.59  ? 68  MET B CE  1 
ATOM   546  N  N   . PHE A 1 69  ? 149.362 126.290 109.131 1.00 79.34  ? 69  PHE B N   1 
ATOM   547  C  CA  . PHE A 1 69  ? 150.163 125.541 108.174 1.00 79.34  ? 69  PHE B CA  1 
ATOM   548  C  C   . PHE A 1 69  ? 149.798 125.843 106.727 1.00 79.34  ? 69  PHE B C   1 
ATOM   549  O  O   . PHE A 1 69  ? 150.397 125.260 105.819 1.00 79.34  ? 69  PHE B O   1 
ATOM   550  C  CB  . PHE A 1 69  ? 150.016 124.038 108.432 1.00 79.34  ? 69  PHE B CB  1 
ATOM   551  C  CG  . PHE A 1 69  ? 150.563 123.596 109.755 1.00 79.34  ? 69  PHE B CG  1 
ATOM   552  C  CD1 . PHE A 1 69  ? 151.845 123.943 110.140 1.00 79.34  ? 69  PHE B CD1 1 
ATOM   553  C  CD2 . PHE A 1 69  ? 149.795 122.834 110.615 1.00 79.34  ? 69  PHE B CD2 1 
ATOM   554  C  CE1 . PHE A 1 69  ? 152.350 123.538 111.358 1.00 79.34  ? 69  PHE B CE1 1 
ATOM   555  C  CE2 . PHE A 1 69  ? 150.295 122.426 111.834 1.00 79.34  ? 69  PHE B CE2 1 
ATOM   556  C  CZ  . PHE A 1 69  ? 151.574 122.779 112.205 1.00 79.34  ? 69  PHE B CZ  1 
ATOM   557  N  N   . GLY A 1 70  ? 148.842 126.739 106.491 1.00 82.92  ? 70  GLY B N   1 
ATOM   558  C  CA  . GLY A 1 70  ? 148.364 127.009 105.154 1.00 82.92  ? 70  GLY B CA  1 
ATOM   559  C  C   . GLY A 1 70  ? 147.138 126.226 104.744 1.00 82.92  ? 70  GLY B C   1 
ATOM   560  O  O   . GLY A 1 70  ? 146.562 126.520 103.689 1.00 82.92  ? 70  GLY B O   1 
ATOM   561  N  N   . ILE A 1 71  ? 146.720 125.243 105.532 1.00 85.57  ? 71  ILE B N   1 
ATOM   562  C  CA  . ILE A 1 71  ? 145.508 124.483 105.258 1.00 85.57  ? 71  ILE B CA  1 
ATOM   563  C  C   . ILE A 1 71  ? 144.354 125.131 106.007 1.00 85.57  ? 71  ILE B C   1 
ATOM   564  O  O   . ILE A 1 71  ? 144.375 125.223 107.239 1.00 85.57  ? 71  ILE B O   1 
ATOM   565  C  CB  . ILE A 1 71  ? 145.675 123.012 105.671 1.00 85.57  ? 71  ILE B CB  1 
ATOM   566  C  CG1 . ILE A 1 71  ? 146.912 122.407 105.008 1.00 85.57  ? 71  ILE B CG1 1 
ATOM   567  C  CG2 . ILE A 1 71  ? 144.432 122.217 105.313 1.00 85.57  ? 71  ILE B CG2 1 
ATOM   568  C  CD1 . ILE A 1 71  ? 147.055 120.919 105.229 1.00 85.57  ? 71  ILE B CD1 1 
ATOM   569  N  N   . MET A 1 72  ? 143.343 125.570 105.272 1.00 93.68  ? 72  MET B N   1 
ATOM   570  C  CA  . MET A 1 72  ? 142.204 126.265 105.845 1.00 93.68  ? 72  MET B CA  1 
ATOM   571  C  C   . MET A 1 72  ? 140.933 125.513 105.488 1.00 93.68  ? 72  MET B C   1 
ATOM   572  O  O   . MET A 1 72  ? 140.902 124.767 104.504 1.00 93.68  ? 72  MET B O   1 
ATOM   573  C  CB  . MET A 1 72  ? 142.110 127.714 105.346 1.00 93.68  ? 72  MET B CB  1 
ATOM   574  C  CG  . MET A 1 72  ? 143.056 128.680 106.041 1.00 93.68  ? 72  MET B CG  1 
ATOM   575  S  SD  . MET A 1 72  ? 144.767 128.521 105.502 1.00 93.68  ? 72  MET B SD  1 
ATOM   576  C  CE  . MET A 1 72  ? 144.785 129.629 104.096 1.00 93.68  ? 72  MET B CE  1 
ATOM   577  N  N   . PRO A 1 73  ? 139.878 125.667 106.286 1.00 98.82  ? 73  PRO B N   1 
ATOM   578  C  CA  . PRO A 1 73  ? 138.585 125.076 105.925 1.00 98.82  ? 73  PRO B CA  1 
ATOM   579  C  C   . PRO A 1 73  ? 138.145 125.529 104.542 1.00 98.82  ? 73  PRO B C   1 
ATOM   580  O  O   . PRO A 1 73  ? 138.285 126.697 104.175 1.00 98.82  ? 73  PRO B O   1 
ATOM   581  C  CB  . PRO A 1 73  ? 137.637 125.596 107.013 1.00 98.82  ? 73  PRO B CB  1 
ATOM   582  C  CG  . PRO A 1 73  ? 138.498 126.262 108.056 1.00 98.82  ? 73  PRO B CG  1 
ATOM   583  C  CD  . PRO A 1 73  ? 139.932 126.058 107.703 1.00 98.82  ? 73  PRO B CD  1 
ATOM   584  N  N   . SER A 1 74  ? 137.608 124.589 103.769 1.00 106.66 ? 74  SER B N   1 
ATOM   585  C  CA  . SER A 1 74  ? 137.230 124.857 102.391 1.00 106.66 ? 74  SER B CA  1 
ATOM   586  C  C   . SER A 1 74  ? 135.868 124.238 102.121 1.00 106.66 ? 74  SER B C   1 
ATOM   587  O  O   . SER A 1 74  ? 135.155 123.825 103.040 1.00 106.66 ? 74  SER B O   1 
ATOM   588  C  CB  . SER A 1 74  ? 138.277 124.320 101.410 1.00 106.66 ? 74  SER B CB  1 
ATOM   589  O  OG  . SER A 1 74  ? 138.323 122.905 101.439 1.00 106.66 ? 74  SER B OG  1 
ATOM   590  N  N   . LYS A 1 75  ? 135.507 124.201 100.836 1.00 117.61 ? 75  LYS B N   1 
ATOM   591  C  CA  . LYS A 1 75  ? 134.253 123.623 100.366 1.00 117.61 ? 75  LYS B CA  1 
ATOM   592  C  C   . LYS A 1 75  ? 133.056 124.385 100.922 1.00 117.61 ? 75  LYS B C   1 
ATOM   593  O  O   . LYS A 1 75  ? 133.205 125.491 101.451 1.00 117.61 ? 75  LYS B O   1 
ATOM   594  C  CB  . LYS A 1 75  ? 134.163 122.139 100.734 1.00 117.61 ? 75  LYS B CB  1 
ATOM   595  N  N   . LYS A 1 76  ? 131.870 123.802 100.807 1.00 126.02 ? 76  LYS B N   1 
ATOM   596  C  CA  . LYS A 1 76  ? 130.643 124.449 101.254 1.00 126.02 ? 76  LYS B CA  1 
ATOM   597  C  C   . LYS A 1 76  ? 129.728 123.373 101.831 1.00 126.02 ? 76  LYS B C   1 
ATOM   598  O  O   . LYS A 1 76  ? 130.140 122.231 102.064 1.00 126.02 ? 76  LYS B O   1 
ATOM   599  C  CB  . LYS A 1 76  ? 130.000 125.233 100.100 1.00 126.02 ? 76  LYS B CB  1 
ATOM   600  C  CG  . LYS A 1 76  ? 129.549 124.364 98.939  1.00 126.02 ? 76  LYS B CG  1 
ATOM   601  C  CD  . LYS A 1 76  ? 128.997 125.206 97.801  1.00 126.02 ? 76  LYS B CD  1 
ATOM   602  C  CE  . LYS A 1 76  ? 128.522 124.333 96.652  1.00 126.02 ? 76  LYS B CE  1 
ATOM   603  N  NZ  . LYS A 1 76  ? 129.651 123.619 95.995  1.00 126.02 ? 76  LYS B NZ  1 
ATOM   604  N  N   . VAL A 1 77  ? 128.470 123.736 102.072 1.00 131.61 ? 77  VAL B N   1 
ATOM   605  C  CA  . VAL A 1 77  ? 127.495 122.819 102.648 1.00 131.61 ? 77  VAL B CA  1 
ATOM   606  C  C   . VAL A 1 77  ? 126.116 123.241 102.154 1.00 131.61 ? 77  VAL B C   1 
ATOM   607  O  O   . VAL A 1 77  ? 125.960 124.321 101.576 1.00 131.61 ? 77  VAL B O   1 
ATOM   608  C  CB  . VAL A 1 77  ? 127.584 122.824 104.188 1.00 131.61 ? 77  VAL B CB  1 
ATOM   609  C  CG1 . VAL A 1 77  ? 127.160 124.178 104.747 1.00 131.61 ? 77  VAL B CG1 1 
ATOM   610  C  CG2 . VAL A 1 77  ? 126.795 121.672 104.812 1.00 131.61 ? 77  VAL B CG2 1 
ATOM   611  N  N   . ALA A 1 78  ? 125.110 122.389 102.355 1.00 133.91 ? 78  ALA B N   1 
ATOM   612  C  CA  . ALA A 1 78  ? 123.716 122.718 102.066 1.00 133.91 ? 78  ALA B CA  1 
ATOM   613  C  C   . ALA A 1 78  ? 122.903 122.576 103.353 1.00 133.91 ? 78  ALA B C   1 
ATOM   614  O  O   . ALA A 1 78  ? 121.807 122.017 103.379 1.00 133.91 ? 78  ALA B O   1 
ATOM   615  C  CB  . ALA A 1 78  ? 123.155 121.839 100.952 1.00 133.91 ? 78  ALA B CB  1 
ATOM   616  N  N   . SER A 1 79  ? 123.466 123.100 104.443 1.00 130.47 ? 79  SER B N   1 
ATOM   617  C  CA  . SER A 1 79  ? 122.898 122.863 105.766 1.00 130.47 ? 79  SER B CA  1 
ATOM   618  C  C   . SER A 1 79  ? 121.615 123.655 105.985 1.00 130.47 ? 79  SER B C   1 
ATOM   619  O  O   . SER A 1 79  ? 120.766 123.249 106.788 1.00 130.47 ? 79  SER B O   1 
ATOM   620  C  CB  . SER A 1 79  ? 123.927 123.209 106.843 1.00 130.47 ? 79  SER B CB  1 
ATOM   621  O  OG  . SER A 1 79  ? 123.486 122.794 108.124 1.00 130.47 ? 79  SER B OG  1 
ATOM   622  N  N   . ALA A 1 80  ? 121.458 124.781 105.290 1.00 123.59 ? 80  ALA B N   1 
ATOM   623  C  CA  . ALA A 1 80  ? 120.377 125.742 105.558 1.00 123.59 ? 80  ALA B CA  1 
ATOM   624  C  C   . ALA A 1 80  ? 120.564 126.176 107.011 1.00 123.59 ? 80  ALA B C   1 
ATOM   625  O  O   . ALA A 1 80  ? 121.617 126.747 107.338 1.00 123.59 ? 80  ALA B O   1 
ATOM   626  C  CB  . ALA A 1 80  ? 119.017 125.146 105.209 1.00 123.59 ? 80  ALA B CB  1 
ATOM   627  N  N   . TYR A 1 81  ? 119.604 125.940 107.902 1.00 102.39 ? 81  TYR B N   1 
ATOM   628  C  CA  . TYR A 1 81  ? 119.837 126.144 109.324 1.00 102.39 ? 81  TYR B CA  1 
ATOM   629  C  C   . TYR A 1 81  ? 119.027 125.134 110.121 1.00 102.39 ? 81  TYR B C   1 
ATOM   630  O  O   . TYR A 1 81  ? 118.039 124.579 109.631 1.00 102.39 ? 81  TYR B O   1 
ATOM   631  C  CB  . TYR A 1 81  ? 119.487 127.565 109.777 1.00 102.39 ? 81  TYR B CB  1 
ATOM   632  C  CG  . TYR A 1 81  ? 120.208 127.963 111.044 1.00 102.39 ? 81  TYR B CG  1 
ATOM   633  C  CD1 . TYR A 1 81  ? 121.527 128.396 111.005 1.00 102.39 ? 81  TYR B CD1 1 
ATOM   634  C  CD2 . TYR A 1 81  ? 119.586 127.875 112.281 1.00 102.39 ? 81  TYR B CD2 1 
ATOM   635  C  CE1 . TYR A 1 81  ? 122.197 128.752 112.159 1.00 102.39 ? 81  TYR B CE1 1 
ATOM   636  C  CE2 . TYR A 1 81  ? 120.251 128.220 113.439 1.00 102.39 ? 81  TYR B CE2 1 
ATOM   637  C  CZ  . TYR A 1 81  ? 121.554 128.662 113.373 1.00 102.39 ? 81  TYR B CZ  1 
ATOM   638  O  OH  . TYR A 1 81  ? 122.217 129.011 114.527 1.00 102.39 ? 81  TYR B OH  1 
ATOM   639  N  N   . PHE A 1 82  ? 119.460 124.907 111.355 1.00 89.82  ? 82  PHE B N   1 
ATOM   640  C  CA  . PHE A 1 82  ? 118.882 123.926 112.278 1.00 89.82  ? 82  PHE B CA  1 
ATOM   641  C  C   . PHE A 1 82  ? 118.905 122.544 111.623 1.00 89.82  ? 82  PHE B C   1 
ATOM   642  O  O   . PHE A 1 82  ? 119.562 122.335 110.598 1.00 89.82  ? 82  PHE B O   1 
ATOM   643  C  CB  . PHE A 1 82  ? 117.505 124.390 112.722 1.00 89.82  ? 82  PHE B CB  1 
ATOM   644  C  CG  . PHE A 1 82  ? 117.525 125.299 113.916 1.00 89.82  ? 82  PHE B CG  1 
ATOM   645  C  CD1 . PHE A 1 82  ? 116.669 126.384 113.991 1.00 89.82  ? 82  PHE B CD1 1 
ATOM   646  C  CD2 . PHE A 1 82  ? 118.391 125.062 114.969 1.00 89.82  ? 82  PHE B CD2 1 
ATOM   647  C  CE1 . PHE A 1 82  ? 116.681 127.219 115.093 1.00 89.82  ? 82  PHE B CE1 1 
ATOM   648  C  CE2 . PHE A 1 82  ? 118.408 125.894 116.072 1.00 89.82  ? 82  PHE B CE2 1 
ATOM   649  C  CZ  . PHE A 1 82  ? 117.552 126.974 116.133 1.00 89.82  ? 82  PHE B CZ  1 
ATOM   650  N  N   . LYS A 1 83  ? 118.176 121.597 112.206 1.00 79.41  ? 83  LYS B N   1 
ATOM   651  C  CA  . LYS A 1 83  ? 118.098 120.231 111.708 1.00 79.41  ? 83  LYS B CA  1 
ATOM   652  C  C   . LYS A 1 83  ? 116.818 119.607 112.239 1.00 79.41  ? 83  LYS B C   1 
ATOM   653  O  O   . LYS A 1 83  ? 116.092 120.207 113.034 1.00 79.41  ? 83  LYS B O   1 
ATOM   654  C  CB  . LYS A 1 83  ? 119.310 119.391 112.131 1.00 79.41  ? 83  LYS B CB  1 
ATOM   655  C  CG  . LYS A 1 83  ? 120.556 119.553 111.277 1.00 79.41  ? 83  LYS B CG  1 
ATOM   656  C  CD  . LYS A 1 83  ? 121.771 118.958 111.967 1.00 79.41  ? 83  LYS B CD  1 
ATOM   657  C  CE  . LYS A 1 83  ? 123.058 119.574 111.450 1.00 79.41  ? 83  LYS B CE  1 
ATOM   658  N  NZ  . LYS A 1 83  ? 124.233 119.160 112.265 1.00 79.41  ? 83  LYS B NZ  1 
ATOM   659  N  N   . ASP A 1 84  ? 116.548 118.387 111.782 1.00 76.80  ? 84  ASP B N   1 
ATOM   660  C  CA  . ASP A 1 84  ? 115.498 117.574 112.375 1.00 76.80  ? 84  ASP B CA  1 
ATOM   661  C  C   . ASP A 1 84  ? 115.961 116.873 113.644 1.00 76.80  ? 84  ASP B C   1 
ATOM   662  O  O   . ASP A 1 84  ? 115.125 116.344 114.383 1.00 76.80  ? 84  ASP B O   1 
ATOM   663  C  CB  . ASP A 1 84  ? 115.001 116.538 111.363 1.00 76.80  ? 84  ASP B CB  1 
ATOM   664  C  CG  . ASP A 1 84  ? 113.543 116.176 111.564 1.00 76.80  ? 84  ASP B CG  1 
ATOM   665  O  OD1 . ASP A 1 84  ? 112.951 115.571 110.646 1.00 76.80  ? 84  ASP B OD1 1 
ATOM   666  O  OD2 . ASP A 1 84  ? 112.987 116.497 112.634 1.00 76.80  ? 84  ASP B OD2 1 
ATOM   667  N  N   . PHE A 1 85  ? 117.266 116.866 113.913 1.00 68.87  ? 85  PHE B N   1 
ATOM   668  C  CA  . PHE A 1 85  ? 117.824 116.180 115.072 1.00 68.87  ? 85  PHE B CA  1 
ATOM   669  C  C   . PHE A 1 85  ? 118.039 117.109 116.259 1.00 68.87  ? 85  PHE B C   1 
ATOM   670  O  O   . PHE A 1 85  ? 117.852 116.694 117.407 1.00 68.87  ? 85  PHE B O   1 
ATOM   671  C  CB  . PHE A 1 85  ? 119.150 115.514 114.702 1.00 68.87  ? 85  PHE B CB  1 
ATOM   672  C  CG  . PHE A 1 85  ? 119.816 114.823 115.852 1.00 68.87  ? 85  PHE B CG  1 
ATOM   673  C  CD1 . PHE A 1 85  ? 119.246 113.702 116.427 1.00 68.87  ? 85  PHE B CD1 1 
ATOM   674  C  CD2 . PHE A 1 85  ? 121.003 115.308 116.374 1.00 68.87  ? 85  PHE B CD2 1 
ATOM   675  C  CE1 . PHE A 1 85  ? 119.854 113.069 117.490 1.00 68.87  ? 85  PHE B CE1 1 
ATOM   676  C  CE2 . PHE A 1 85  ? 121.615 114.679 117.438 1.00 68.87  ? 85  PHE B CE2 1 
ATOM   677  C  CZ  . PHE A 1 85  ? 121.040 113.558 117.997 1.00 68.87  ? 85  PHE B CZ  1 
ATOM   678  N  N   . HIS A 1 86  ? 118.439 118.357 116.008 1.00 69.59  ? 86  HIS B N   1 
ATOM   679  C  CA  . HIS A 1 86  ? 118.668 119.290 117.107 1.00 69.59  ? 86  HIS B CA  1 
ATOM   680  C  C   . HIS A 1 86  ? 117.385 119.547 117.885 1.00 69.59  ? 86  HIS B C   1 
ATOM   681  O  O   . HIS A 1 86  ? 117.401 119.615 119.119 1.00 69.59  ? 86  HIS B O   1 
ATOM   682  C  CB  . HIS A 1 86  ? 119.241 120.600 116.570 1.00 69.59  ? 86  HIS B CB  1 
ATOM   683  C  CG  . HIS A 1 86  ? 120.709 120.547 116.286 1.00 69.59  ? 86  HIS B CG  1 
ATOM   684  N  ND1 . HIS A 1 86  ? 121.220 120.096 115.088 1.00 69.59  ? 86  HIS B ND1 1 
ATOM   685  C  CD2 . HIS A 1 86  ? 121.777 120.892 117.043 1.00 69.59  ? 86  HIS B CD2 1 
ATOM   686  C  CE1 . HIS A 1 86  ? 122.539 120.163 115.120 1.00 69.59  ? 86  HIS B CE1 1 
ATOM   687  N  NE2 . HIS A 1 86  ? 122.902 120.643 116.295 1.00 69.59  ? 86  HIS B NE2 1 
ATOM   688  N  N   . LEU A 1 87  ? 116.263 119.691 117.179 1.00 65.08  ? 87  LEU B N   1 
ATOM   689  C  CA  . LEU A 1 87  ? 114.986 119.932 117.841 1.00 65.08  ? 87  LEU B CA  1 
ATOM   690  C  C   . LEU A 1 87  ? 114.571 118.744 118.703 1.00 65.08  ? 87  LEU B C   1 
ATOM   691  O  O   . LEU A 1 87  ? 114.123 118.916 119.846 1.00 65.08  ? 87  LEU B O   1 
ATOM   692  C  CB  . LEU A 1 87  ? 113.923 120.237 116.790 1.00 65.08  ? 87  LEU B CB  1 
ATOM   693  C  CG  . LEU A 1 87  ? 114.295 121.322 115.778 1.00 65.08  ? 87  LEU B CG  1 
ATOM   694  C  CD1 . LEU A 1 87  ? 113.158 121.565 114.804 1.00 65.08  ? 87  LEU B CD1 1 
ATOM   695  C  CD2 . LEU A 1 87  ? 114.675 122.607 116.491 1.00 65.08  ? 87  LEU B CD2 1 
ATOM   696  N  N   . LEU A 1 88  ? 114.718 117.529 118.171 1.00 62.58  ? 88  LEU B N   1 
ATOM   697  C  CA  . LEU A 1 88  ? 114.408 116.334 118.945 1.00 62.58  ? 88  LEU B CA  1 
ATOM   698  C  C   . LEU A 1 88  ? 115.300 116.233 120.173 1.00 62.58  ? 88  LEU B C   1 
ATOM   699  O  O   . LEU A 1 88  ? 114.838 115.874 121.264 1.00 62.58  ? 88  LEU B O   1 
ATOM   700  C  CB  . LEU A 1 88  ? 114.563 115.095 118.066 1.00 62.58  ? 88  LEU B CB  1 
ATOM   701  C  CG  . LEU A 1 88  ? 114.414 113.739 118.747 1.00 62.58  ? 88  LEU B CG  1 
ATOM   702  C  CD1 . LEU A 1 88  ? 113.006 113.579 119.271 1.00 62.58  ? 88  LEU B CD1 1 
ATOM   703  C  CD2 . LEU A 1 88  ? 114.760 112.620 117.782 1.00 62.58  ? 88  LEU B CD2 1 
ATOM   704  N  N   . LEU A 1 89  ? 116.586 116.547 120.012 1.00 58.75  ? 89  LEU B N   1 
ATOM   705  C  CA  . LEU A 1 89  ? 117.508 116.517 121.140 1.00 58.75  ? 89  LEU B CA  1 
ATOM   706  C  C   . LEU A 1 89  ? 117.105 117.524 122.207 1.00 58.75  ? 89  LEU B C   1 
ATOM   707  O  O   . LEU A 1 89  ? 117.157 117.223 123.404 1.00 58.75  ? 89  LEU B O   1 
ATOM   708  C  CB  . LEU A 1 89  ? 118.927 116.787 120.648 1.00 58.75  ? 89  LEU B CB  1 
ATOM   709  C  CG  . LEU A 1 89  ? 120.033 116.906 121.691 1.00 58.75  ? 89  LEU B CG  1 
ATOM   710  C  CD1 . LEU A 1 89  ? 120.062 115.674 122.574 1.00 58.75  ? 89  LEU B CD1 1 
ATOM   711  C  CD2 . LEU A 1 89  ? 121.363 117.105 120.991 1.00 58.75  ? 89  LEU B CD2 1 
ATOM   712  N  N   . ILE A 1 90  ? 116.696 118.725 121.792 1.00 56.31  ? 90  ILE B N   1 
ATOM   713  C  CA  . ILE A 1 90  ? 116.271 119.738 122.754 1.00 56.31  ? 90  ILE B CA  1 
ATOM   714  C  C   . ILE A 1 90  ? 115.037 119.266 123.514 1.00 56.31  ? 90  ILE B C   1 
ATOM   715  O  O   . ILE A 1 90  ? 114.943 119.428 124.738 1.00 56.31  ? 90  ILE B O   1 
ATOM   716  C  CB  . ILE A 1 90  ? 116.024 121.082 122.044 1.00 56.31  ? 90  ILE B CB  1 
ATOM   717  C  CG1 . ILE A 1 90  ? 117.340 121.659 121.524 1.00 56.31  ? 90  ILE B CG1 1 
ATOM   718  C  CG2 . ILE A 1 90  ? 115.380 122.074 122.990 1.00 56.31  ? 90  ILE B CG2 1 
ATOM   719  C  CD1 . ILE A 1 90  ? 117.181 122.948 120.748 1.00 56.31  ? 90  ILE B CD1 1 
ATOM   720  N  N   . GLY A 1 91  ? 114.074 118.672 122.805 1.00 54.24  ? 91  GLY B N   1 
ATOM   721  C  CA  . GLY A 1 91  ? 112.894 118.152 123.481 1.00 54.24  ? 91  GLY B CA  1 
ATOM   722  C  C   . GLY A 1 91  ? 113.222 117.060 124.484 1.00 54.24  ? 91  GLY B C   1 
ATOM   723  O  O   . GLY A 1 91  ? 112.712 117.057 125.613 1.00 54.24  ? 91  GLY B O   1 
ATOM   724  N  N   . VAL A 1 92  ? 114.089 116.123 124.094 1.00 51.50  ? 92  VAL B N   1 
ATOM   725  C  CA  . VAL A 1 92  ? 114.459 115.036 124.997 1.00 51.50  ? 92  VAL B CA  1 
ATOM   726  C  C   . VAL A 1 92  ? 115.206 115.577 126.209 1.00 51.50  ? 92  VAL B C   1 
ATOM   727  O  O   . VAL A 1 92  ? 115.035 115.086 127.331 1.00 51.50  ? 92  VAL B O   1 
ATOM   728  C  CB  . VAL A 1 92  ? 115.283 113.972 124.252 1.00 51.50  ? 92  VAL B CB  1 
ATOM   729  C  CG1 . VAL A 1 92  ? 115.781 112.924 125.224 1.00 51.50  ? 92  VAL B CG1 1 
ATOM   730  C  CG2 . VAL A 1 92  ? 114.447 113.324 123.166 1.00 51.50  ? 92  VAL B CG2 1 
ATOM   731  N  N   . ILE A 1 93  ? 116.045 116.595 126.009 1.00 52.06  ? 93  ILE B N   1 
ATOM   732  C  CA  . ILE A 1 93  ? 116.774 117.168 127.136 1.00 52.06  ? 93  ILE B CA  1 
ATOM   733  C  C   . ILE A 1 93  ? 115.822 117.894 128.077 1.00 52.06  ? 93  ILE B C   1 
ATOM   734  O  O   . ILE A 1 93  ? 115.995 117.857 129.301 1.00 52.06  ? 93  ILE B O   1 
ATOM   735  C  CB  . ILE A 1 93  ? 117.902 118.087 126.638 1.00 52.06  ? 93  ILE B CB  1 
ATOM   736  C  CG1 . ILE A 1 93  ? 118.978 117.264 125.931 1.00 52.06  ? 93  ILE B CG1 1 
ATOM   737  C  CG2 . ILE A 1 93  ? 118.524 118.833 127.800 1.00 52.06  ? 93  ILE B CG2 1 
ATOM   738  C  CD1 . ILE A 1 93  ? 119.467 116.079 126.729 1.00 52.06  ? 93  ILE B CD1 1 
ATOM   739  N  N   . CYS A 1 94  ? 114.804 118.563 127.531 1.00 51.34  ? 94  CYS B N   1 
ATOM   740  C  CA  . CYS A 1 94  ? 113.775 119.156 128.383 1.00 51.34  ? 94  CYS B CA  1 
ATOM   741  C  C   . CYS A 1 94  ? 113.105 118.089 129.237 1.00 51.34  ? 94  CYS B C   1 
ATOM   742  O  O   . CYS A 1 94  ? 112.930 118.259 130.453 1.00 51.34  ? 94  CYS B O   1 
ATOM   743  C  CB  . CYS A 1 94  ? 112.733 119.880 127.530 1.00 51.34  ? 94  CYS B CB  1 
ATOM   744  S  SG  . CYS A 1 94  ? 113.277 121.429 126.793 1.00 51.34  ? 94  CYS B SG  1 
ATOM   745  N  N   . LEU A 1 95  ? 112.734 116.971 128.610 1.00 51.25  ? 95  LEU B N   1 
ATOM   746  C  CA  . LEU A 1 95  ? 112.095 115.883 129.345 1.00 51.25  ? 95  LEU B CA  1 
ATOM   747  C  C   . LEU A 1 95  ? 113.007 115.351 130.446 1.00 51.25  ? 95  LEU B C   1 
ATOM   748  O  O   . LEU A 1 95  ? 112.571 115.137 131.584 1.00 51.25  ? 95  LEU B O   1 
ATOM   749  C  CB  . LEU A 1 95  ? 111.712 114.763 128.381 1.00 51.25  ? 95  LEU B CB  1 
ATOM   750  C  CG  . LEU A 1 95  ? 111.111 113.507 129.005 1.00 51.25  ? 95  LEU B CG  1 
ATOM   751  C  CD1 . LEU A 1 95  ? 109.864 113.851 129.800 1.00 51.25  ? 95  LEU B CD1 1 
ATOM   752  C  CD2 . LEU A 1 95  ? 110.813 112.477 127.933 1.00 51.25  ? 95  LEU B CD2 1 
ATOM   753  N  N   . ALA A 1 96  ? 114.282 115.134 130.119 1.00 50.22  ? 96  ALA B N   1 
ATOM   754  C  CA  . ALA A 1 96  ? 115.223 114.589 131.093 1.00 50.22  ? 96  ALA B CA  1 
ATOM   755  C  C   . ALA A 1 96  ? 115.445 115.552 132.251 1.00 50.22  ? 96  ALA B C   1 
ATOM   756  O  O   . ALA A 1 96  ? 115.524 115.127 133.409 1.00 50.22  ? 96  ALA B O   1 
ATOM   757  C  CB  . ALA A 1 96  ? 116.548 114.255 130.412 1.00 50.22  ? 96  ALA B CB  1 
ATOM   758  N  N   . THR A 1 97  ? 115.558 116.849 131.960 1.00 50.79  ? 97  THR B N   1 
ATOM   759  C  CA  . THR A 1 97  ? 115.740 117.837 133.017 1.00 50.79  ? 97  THR B CA  1 
ATOM   760  C  C   . THR A 1 97  ? 114.539 117.865 133.950 1.00 50.79  ? 97  THR B C   1 
ATOM   761  O  O   . THR A 1 97  ? 114.690 117.894 135.178 1.00 50.79  ? 97  THR B O   1 
ATOM   762  C  CB  . THR A 1 97  ? 115.973 119.217 132.404 1.00 50.79  ? 97  THR B CB  1 
ATOM   763  O  OG1 . THR A 1 97  ? 116.872 119.104 131.295 1.00 50.79  ? 97  THR B OG1 1 
ATOM   764  C  CG2 . THR A 1 97  ? 116.560 120.164 133.435 1.00 50.79  ? 97  THR B CG2 1 
ATOM   765  N  N   . SER A 1 98  ? 113.331 117.852 133.381 1.00 51.02  ? 98  SER B N   1 
ATOM   766  C  CA  . SER A 1 98  ? 112.137 117.860 134.219 1.00 51.02  ? 98  SER B CA  1 
ATOM   767  C  C   . SER A 1 98  ? 112.054 116.601 135.070 1.00 51.02  ? 98  SER B C   1 
ATOM   768  O  O   . SER A 1 98  ? 111.660 116.660 136.240 1.00 51.02  ? 98  SER B O   1 
ATOM   769  C  CB  . SER A 1 98  ? 110.887 118.007 133.357 1.00 51.02  ? 98  SER B CB  1 
ATOM   770  O  OG  . SER A 1 98  ? 109.719 117.839 134.140 1.00 51.02  ? 98  SER B OG  1 
ATOM   771  N  N   . ILE A 1 99  ? 112.417 115.450 134.500 1.00 53.27  ? 99  ILE B N   1 
ATOM   772  C  CA  . ILE A 1 99  ? 112.401 114.205 135.265 1.00 53.27  ? 99  ILE B CA  1 
ATOM   773  C  C   . ILE A 1 99  ? 113.404 114.272 136.410 1.00 53.27  ? 99  ILE B C   1 
ATOM   774  O  O   . ILE A 1 99  ? 113.104 113.895 137.548 1.00 53.27  ? 99  ILE B O   1 
ATOM   775  C  CB  . ILE A 1 99  ? 112.681 113.005 134.343 1.00 53.27  ? 99  ILE B CB  1 
ATOM   776  C  CG1 . ILE A 1 99  ? 111.451 112.674 133.502 1.00 53.27  ? 99  ILE B CG1 1 
ATOM   777  C  CG2 . ILE A 1 99  ? 113.102 111.793 135.151 1.00 53.27  ? 99  ILE B CG2 1 
ATOM   778  C  CD1 . ILE A 1 99  ? 111.707 111.616 132.459 1.00 53.27  ? 99  ILE B CD1 1 
ATOM   779  N  N   . GLU A 1 100 ? 114.610 114.766 136.125 1.00 59.22  ? 100 GLU B N   1 
ATOM   780  C  CA  . GLU A 1 100 ? 115.690 114.700 137.102 1.00 59.22  ? 100 GLU B CA  1 
ATOM   781  C  C   . GLU A 1 100 ? 115.476 115.683 138.246 1.00 59.22  ? 100 GLU B C   1 
ATOM   782  O  O   . GLU A 1 100 ? 115.656 115.331 139.418 1.00 59.22  ? 100 GLU B O   1 
ATOM   783  C  CB  . GLU A 1 100 ? 117.030 114.958 136.412 1.00 59.22  ? 100 GLU B CB  1 
ATOM   784  C  CG  . GLU A 1 100 ? 118.242 114.803 137.314 1.00 59.22  ? 100 GLU B CG  1 
ATOM   785  C  CD  . GLU A 1 100 ? 118.693 116.118 137.921 1.00 59.22  ? 100 GLU B CD  1 
ATOM   786  O  OE1 . GLU A 1 100 ? 118.058 117.154 137.635 1.00 59.22  ? 100 GLU B OE1 1 
ATOM   787  O  OE2 . GLU A 1 100 ? 119.684 116.115 138.681 1.00 59.22  ? 100 GLU B OE2 1 
ATOM   788  N  N   . LYS A 1 101 ? 115.091 116.923 137.932 1.00 58.31  ? 101 LYS B N   1 
ATOM   789  C  CA  . LYS A 1 101 ? 115.061 117.953 138.967 1.00 58.31  ? 101 LYS B CA  1 
ATOM   790  C  C   . LYS A 1 101 ? 113.962 117.726 139.998 1.00 58.31  ? 101 LYS B C   1 
ATOM   791  O  O   . LYS A 1 101 ? 113.995 118.354 141.061 1.00 58.31  ? 101 LYS B O   1 
ATOM   792  C  CB  . LYS A 1 101 ? 114.902 119.338 138.340 1.00 58.31  ? 101 LYS B CB  1 
ATOM   793  C  CG  . LYS A 1 101 ? 113.496 119.658 137.883 1.00 58.31  ? 101 LYS B CG  1 
ATOM   794  C  CD  . LYS A 1 101 ? 113.329 121.143 137.614 1.00 58.31  ? 101 LYS B CD  1 
ATOM   795  C  CE  . LYS A 1 101 ? 113.165 121.922 138.908 1.00 58.31  ? 101 LYS B CE  1 
ATOM   796  N  NZ  . LYS A 1 101 ? 112.742 123.328 138.662 1.00 58.31  ? 101 LYS B NZ  1 
ATOM   797  N  N   . TRP A 1 102 ? 112.995 116.852 139.719 1.00 59.69  ? 102 TRP B N   1 
ATOM   798  C  CA  . TRP A 1 102 ? 111.930 116.546 140.665 1.00 59.69  ? 102 TRP B CA  1 
ATOM   799  C  C   . TRP A 1 102 ? 112.055 115.151 141.263 1.00 59.69  ? 102 TRP B C   1 
ATOM   800  O  O   . TRP A 1 102 ? 111.137 114.703 141.959 1.00 59.69  ? 102 TRP B O   1 
ATOM   801  C  CB  . TRP A 1 102 ? 110.564 116.716 139.998 1.00 59.69  ? 102 TRP B CB  1 
ATOM   802  C  CG  . TRP A 1 102 ? 110.336 118.102 139.500 1.00 59.69  ? 102 TRP B CG  1 
ATOM   803  C  CD1 . TRP A 1 102 ? 110.335 118.515 138.204 1.00 59.69  ? 102 TRP B CD1 1 
ATOM   804  C  CD2 . TRP A 1 102 ? 110.089 119.269 140.293 1.00 59.69  ? 102 TRP B CD2 1 
ATOM   805  N  NE1 . TRP A 1 102 ? 110.100 119.865 138.137 1.00 59.69  ? 102 TRP B NE1 1 
ATOM   806  C  CE2 . TRP A 1 102 ? 109.943 120.351 139.407 1.00 59.69  ? 102 TRP B CE2 1 
ATOM   807  C  CE3 . TRP A 1 102 ? 109.972 119.501 141.666 1.00 59.69  ? 102 TRP B CE3 1 
ATOM   808  C  CZ2 . TRP A 1 102 ? 109.688 121.646 139.847 1.00 59.69  ? 102 TRP B CZ2 1 
ATOM   809  C  CZ3 . TRP A 1 102 ? 109.720 120.787 142.100 1.00 59.69  ? 102 TRP B CZ3 1 
ATOM   810  C  CH2 . TRP A 1 102 ? 109.580 121.843 141.194 1.00 59.69  ? 102 TRP B CH2 1 
ATOM   811  N  N   . ASN A 1 103 ? 113.166 114.459 141.010 1.00 65.02  ? 103 ASN B N   1 
ATOM   812  C  CA  . ASN A 1 103 ? 113.447 113.150 141.602 1.00 65.02  ? 103 ASN B CA  1 
ATOM   813  C  C   . ASN A 1 103 ? 112.340 112.141 141.298 1.00 65.02  ? 103 ASN B C   1 
ATOM   814  O  O   . ASN A 1 103 ? 111.935 111.351 142.151 1.00 65.02  ? 103 ASN B O   1 
ATOM   815  C  CB  . ASN A 1 103 ? 113.676 113.273 143.110 1.00 65.02  ? 103 ASN B CB  1 
ATOM   816  C  CG  . ASN A 1 103 ? 114.721 114.312 143.456 1.00 65.02  ? 103 ASN B CG  1 
ATOM   817  O  OD1 . ASN A 1 103 ? 115.492 114.740 142.599 1.00 65.02  ? 103 ASN B OD1 1 
ATOM   818  N  ND2 . ASN A 1 103 ? 114.752 114.724 144.717 1.00 65.02  ? 103 ASN B ND2 1 
ATOM   819  N  N   . LEU A 1 104 ? 111.841 112.180 140.061 1.00 63.99  ? 104 LEU B N   1 
ATOM   820  C  CA  . LEU A 1 104 ? 110.898 111.161 139.614 1.00 63.99  ? 104 LEU B CA  1 
ATOM   821  C  C   . LEU A 1 104 ? 111.600 109.849 139.290 1.00 63.99  ? 104 LEU B C   1 
ATOM   822  O  O   . LEU A 1 104 ? 111.018 108.772 139.477 1.00 63.99  ? 104 LEU B O   1 
ATOM   823  C  CB  . LEU A 1 104 ? 110.124 111.660 138.394 1.00 63.99  ? 104 LEU B CB  1 
ATOM   824  C  CG  . LEU A 1 104 ? 109.128 110.686 137.767 1.00 63.99  ? 104 LEU B CG  1 
ATOM   825  C  CD1 . LEU A 1 104 ? 108.011 110.370 138.743 1.00 63.99  ? 104 LEU B CD1 1 
ATOM   826  C  CD2 . LEU A 1 104 ? 108.568 111.247 136.474 1.00 63.99  ? 104 LEU B CD2 1 
ATOM   827  N  N   . HIS A 1 105 ? 112.847 109.920 138.816 1.00 64.74  ? 105 HIS B N   1 
ATOM   828  C  CA  . HIS A 1 105 ? 113.583 108.708 138.475 1.00 64.74  ? 105 HIS B CA  1 
ATOM   829  C  C   . HIS A 1 105 ? 113.800 107.834 139.701 1.00 64.74  ? 105 HIS B C   1 
ATOM   830  O  O   . HIS A 1 105 ? 113.767 106.602 139.607 1.00 64.74  ? 105 HIS B O   1 
ATOM   831  C  CB  . HIS A 1 105 ? 114.919 109.067 137.829 1.00 64.74  ? 105 HIS B CB  1 
ATOM   832  C  CG  . HIS A 1 105 ? 115.642 110.184 138.512 1.00 64.74  ? 105 HIS B CG  1 
ATOM   833  N  ND1 . HIS A 1 105 ? 116.329 110.014 139.694 1.00 64.74  ? 105 HIS B ND1 1 
ATOM   834  C  CD2 . HIS A 1 105 ? 115.793 111.486 138.174 1.00 64.74  ? 105 HIS B CD2 1 
ATOM   835  C  CE1 . HIS A 1 105 ? 116.869 111.164 140.057 1.00 64.74  ? 105 HIS B CE1 1 
ATOM   836  N  NE2 . HIS A 1 105 ? 116.558 112.073 139.152 1.00 64.74  ? 105 HIS B NE2 1 
ATOM   837  N  N   . LYS A 1 106 ? 114.033 108.452 140.861 1.00 66.88  ? 106 LYS B N   1 
ATOM   838  C  CA  . LYS A 1 106 ? 114.158 107.675 142.088 1.00 66.88  ? 106 LYS B CA  1 
ATOM   839  C  C   . LYS A 1 106 ? 112.873 106.915 142.385 1.00 66.88  ? 106 LYS B C   1 
ATOM   840  O  O   . LYS A 1 106 ? 112.912 105.732 142.745 1.00 66.88  ? 106 LYS B O   1 
ATOM   841  C  CB  . LYS A 1 106 ? 114.523 108.588 143.257 1.00 66.88  ? 106 LYS B CB  1 
ATOM   842  C  CG  . LYS A 1 106 ? 115.861 109.283 143.104 1.00 66.88  ? 106 LYS B CG  1 
ATOM   843  C  CD  . LYS A 1 106 ? 115.994 110.445 144.070 1.00 66.88  ? 106 LYS B CD  1 
ATOM   844  C  CE  . LYS A 1 106 ? 117.429 110.609 144.539 1.00 66.88  ? 106 LYS B CE  1 
ATOM   845  N  NZ  . LYS A 1 106 ? 117.501 110.986 145.977 1.00 66.88  ? 106 LYS B NZ  1 
ATOM   846  N  N   . ARG A 1 107 ? 111.723 107.573 142.230 1.00 67.78  ? 107 ARG B N   1 
ATOM   847  C  CA  . ARG A 1 107 ? 110.455 106.896 142.470 1.00 67.78  ? 107 ARG B CA  1 
ATOM   848  C  C   . ARG A 1 107 ? 110.258 105.743 141.498 1.00 67.78  ? 107 ARG B C   1 
ATOM   849  O  O   . ARG A 1 107 ? 109.826 104.655 141.896 1.00 67.78  ? 107 ARG B O   1 
ATOM   850  C  CB  . ARG A 1 107 ? 109.297 107.885 142.369 1.00 67.78  ? 107 ARG B CB  1 
ATOM   851  C  CG  . ARG A 1 107 ? 107.976 107.326 142.865 1.00 67.78  ? 107 ARG B CG  1 
ATOM   852  C  CD  . ARG A 1 107 ? 106.937 108.418 143.018 1.00 67.78  ? 107 ARG B CD  1 
ATOM   853  N  NE  . ARG A 1 107 ? 107.495 109.609 143.645 1.00 67.78  ? 107 ARG B NE  1 
ATOM   854  C  CZ  . ARG A 1 107 ? 107.380 109.899 144.933 1.00 67.78  ? 107 ARG B CZ  1 
ATOM   855  N  NH1 . ARG A 1 107 ? 106.728 109.104 145.764 1.00 67.78  ? 107 ARG B NH1 1 
ATOM   856  N  NH2 . ARG A 1 107 ? 107.935 111.015 145.398 1.00 67.78  ? 107 ARG B NH2 1 
ATOM   857  N  N   . ILE A 1 108 ? 110.584 105.955 140.221 1.00 64.36  ? 108 ILE B N   1 
ATOM   858  C  CA  . ILE A 1 108 ? 110.427 104.894 139.227 1.00 64.36  ? 108 ILE B CA  1 
ATOM   859  C  C   . ILE A 1 108 ? 111.317 103.705 139.569 1.00 64.36  ? 108 ILE B C   1 
ATOM   860  O  O   . ILE A 1 108 ? 110.881 102.545 139.536 1.00 64.36  ? 108 ILE B O   1 
ATOM   861  C  CB  . ILE A 1 108 ? 110.728 105.432 137.817 1.00 64.36  ? 108 ILE B CB  1 
ATOM   862  C  CG1 . ILE A 1 108 ? 109.788 106.583 137.467 1.00 64.36  ? 108 ILE B CG1 1 
ATOM   863  C  CG2 . ILE A 1 108 ? 110.612 104.325 136.790 1.00 64.36  ? 108 ILE B CG2 1 
ATOM   864  C  CD1 . ILE A 1 108 ? 110.056 107.187 136.109 1.00 64.36  ? 108 ILE B CD1 1 
ATOM   865  N  N   . ALA A 1 109 ? 112.582 103.976 139.899 1.00 63.16  ? 109 ALA B N   1 
ATOM   866  C  CA  . ALA A 1 109 ? 113.523 102.902 140.195 1.00 63.16  ? 109 ALA B CA  1 
ATOM   867  C  C   . ALA A 1 109 ? 113.095 102.120 141.429 1.00 63.16  ? 109 ALA B C   1 
ATOM   868  O  O   . ALA A 1 109 ? 113.116 100.883 141.430 1.00 63.16  ? 109 ALA B O   1 
ATOM   869  C  CB  . ALA A 1 109 ? 114.928 103.474 140.379 1.00 63.16  ? 109 ALA B CB  1 
ATOM   870  N  N   . LEU A 1 110 ? 112.699 102.823 142.492 1.00 67.52  ? 110 LEU B N   1 
ATOM   871  C  CA  . LEU A 1 110 ? 112.260 102.133 143.700 1.00 67.52  ? 110 LEU B CA  1 
ATOM   872  C  C   . LEU A 1 110 ? 110.995 101.326 143.446 1.00 67.52  ? 110 LEU B C   1 
ATOM   873  O  O   . LEU A 1 110 ? 110.852 100.210 143.959 1.00 67.52  ? 110 LEU B O   1 
ATOM   874  C  CB  . LEU A 1 110 ? 112.047 103.129 144.839 1.00 67.52  ? 110 LEU B CB  1 
ATOM   875  C  CG  . LEU A 1 110 ? 113.259 103.460 145.716 1.00 67.52  ? 110 LEU B CG  1 
ATOM   876  C  CD1 . LEU A 1 110 ? 113.716 102.216 146.458 1.00 67.52  ? 110 LEU B CD1 1 
ATOM   877  C  CD2 . LEU A 1 110 ? 114.406 104.052 144.922 1.00 67.52  ? 110 LEU B CD2 1 
ATOM   878  N  N   . LYS A 1 111 ? 110.065 101.867 142.654 1.00 71.68  ? 111 LYS B N   1 
ATOM   879  C  CA  . LYS A 1 111 ? 108.848 101.127 142.350 1.00 71.68  ? 111 LYS B CA  1 
ATOM   880  C  C   . LYS A 1 111 ? 109.158 99.842  141.597 1.00 71.68  ? 111 LYS B C   1 
ATOM   881  O  O   . LYS A 1 111 ? 108.627 98.778  141.934 1.00 71.68  ? 111 LYS B O   1 
ATOM   882  C  CB  . LYS A 1 111 ? 107.887 102.002 141.546 1.00 71.68  ? 111 LYS B CB  1 
ATOM   883  C  CG  . LYS A 1 111 ? 106.573 101.320 141.207 1.00 71.68  ? 111 LYS B CG  1 
ATOM   884  C  CD  . LYS A 1 111 ? 105.881 100.793 142.451 1.00 71.68  ? 111 LYS B CD  1 
ATOM   885  C  CE  . LYS A 1 111 ? 105.391 101.928 143.329 1.00 71.68  ? 111 LYS B CE  1 
ATOM   886  N  NZ  . LYS A 1 111 ? 104.686 101.429 144.539 1.00 71.68  ? 111 LYS B NZ  1 
ATOM   887  N  N   . MET A 1 112 ? 110.025 99.913  140.583 1.00 69.07  ? 112 MET B N   1 
ATOM   888  C  CA  . MET A 1 112 ? 110.372 98.698  139.849 1.00 69.07  ? 112 MET B CA  1 
ATOM   889  C  C   . MET A 1 112 ? 111.096 97.697  140.740 1.00 69.07  ? 112 MET B C   1 
ATOM   890  O  O   . MET A 1 112 ? 110.806 96.494  140.693 1.00 69.07  ? 112 MET B O   1 
ATOM   891  C  CB  . MET A 1 112 ? 111.213 99.029  138.617 1.00 69.07  ? 112 MET B CB  1 
ATOM   892  C  CG  . MET A 1 112 ? 110.463 99.795  137.542 1.00 69.07  ? 112 MET B CG  1 
ATOM   893  S  SD  . MET A 1 112 ? 111.492 100.167 136.112 1.00 69.07  ? 112 MET B SD  1 
ATOM   894  C  CE  . MET A 1 112 ? 110.354 101.126 135.120 1.00 69.07  ? 112 MET B CE  1 
ATOM   895  N  N   . VAL A 1 113 ? 112.033 98.170  141.566 1.00 71.15  ? 113 VAL B N   1 
ATOM   896  C  CA  . VAL A 1 113 ? 112.777 97.263  142.437 1.00 71.15  ? 113 VAL B CA  1 
ATOM   897  C  C   . VAL A 1 113 ? 111.834 96.557  143.403 1.00 71.15  ? 113 VAL B C   1 
ATOM   898  O  O   . VAL A 1 113 ? 111.939 95.344  143.620 1.00 71.15  ? 113 VAL B O   1 
ATOM   899  C  CB  . VAL A 1 113 ? 113.887 98.026  143.182 1.00 71.15  ? 113 VAL B CB  1 
ATOM   900  C  CG1 . VAL A 1 113 ? 114.431 97.191  144.326 1.00 71.15  ? 113 VAL B CG1 1 
ATOM   901  C  CG2 . VAL A 1 113 ? 115.002 98.399  142.224 1.00 71.15  ? 113 VAL B CG2 1 
ATOM   902  N  N   . MET A 1 114 ? 110.895 97.300  143.993 1.00 78.27  ? 114 MET B N   1 
ATOM   903  C  CA  . MET A 1 114 ? 109.941 96.689  144.911 1.00 78.27  ? 114 MET B CA  1 
ATOM   904  C  C   . MET A 1 114 ? 109.012 95.723  144.185 1.00 78.27  ? 114 MET B C   1 
ATOM   905  O  O   . MET A 1 114 ? 108.673 94.660  144.717 1.00 78.27  ? 114 MET B O   1 
ATOM   906  C  CB  . MET A 1 114 ? 109.136 97.773  145.626 1.00 78.27  ? 114 MET B CB  1 
ATOM   907  C  CG  . MET A 1 114 ? 108.062 97.236  146.554 1.00 78.27  ? 114 MET B CG  1 
ATOM   908  S  SD  . MET A 1 114 ? 107.152 98.542  147.397 1.00 78.27  ? 114 MET B SD  1 
ATOM   909  C  CE  . MET A 1 114 ? 105.815 98.818  146.239 1.00 78.27  ? 114 MET B CE  1 
ATOM   910  N  N   . MET A 1 115 ? 108.594 96.071  142.965 1.00 79.52  ? 115 MET B N   1 
ATOM   911  C  CA  . MET A 1 115 ? 107.595 95.271  142.269 1.00 79.52  ? 115 MET B CA  1 
ATOM   912  C  C   . MET A 1 115 ? 108.171 93.969  141.726 1.00 79.52  ? 115 MET B C   1 
ATOM   913  O  O   . MET A 1 115 ? 107.467 92.953  141.699 1.00 79.52  ? 115 MET B O   1 
ATOM   914  C  CB  . MET A 1 115 ? 106.975 96.091  141.138 1.00 79.52  ? 115 MET B CB  1 
ATOM   915  C  CG  . MET A 1 115 ? 105.891 95.370  140.357 1.00 79.52  ? 115 MET B CG  1 
ATOM   916  S  SD  . MET A 1 115 ? 105.512 96.186  138.795 1.00 79.52  ? 115 MET B SD  1 
ATOM   917  C  CE  . MET A 1 115 ? 105.507 97.903  139.304 1.00 79.52  ? 115 MET B CE  1 
ATOM   918  N  N   . VAL A 1 116 ? 109.435 93.971  141.290 1.00 79.06  ? 116 VAL B N   1 
ATOM   919  C  CA  . VAL A 1 116 ? 109.981 92.794  140.614 1.00 79.06  ? 116 VAL B CA  1 
ATOM   920  C  C   . VAL A 1 116 ? 109.995 91.587  141.546 1.00 79.06  ? 116 VAL B C   1 
ATOM   921  O  O   . VAL A 1 116 ? 109.569 90.489  141.165 1.00 79.06  ? 116 VAL B O   1 
ATOM   922  C  CB  . VAL A 1 116 ? 111.381 93.093  140.050 1.00 79.06  ? 116 VAL B CB  1 
ATOM   923  C  CG1 . VAL A 1 116 ? 112.074 91.803  139.663 1.00 79.06  ? 116 VAL B CG1 1 
ATOM   924  C  CG2 . VAL A 1 116 ? 111.272 93.998  138.839 1.00 79.06  ? 116 VAL B CG2 1 
ATOM   925  N  N   . GLY A 1 117 ? 110.469 91.762  142.768 1.00 82.85  ? 117 GLY B N   1 
ATOM   926  C  CA  . GLY A 1 117 ? 110.461 90.684  143.733 1.00 82.85  ? 117 GLY B CA  1 
ATOM   927  C  C   . GLY A 1 117 ? 111.555 90.863  144.765 1.00 82.85  ? 117 GLY B C   1 
ATOM   928  O  O   . GLY A 1 117 ? 112.212 91.897  144.833 1.00 82.85  ? 117 GLY B O   1 
ATOM   929  N  N   . VAL A 1 118 ? 111.732 89.819  145.573 1.00 89.51  ? 118 VAL B N   1 
ATOM   930  C  CA  . VAL A 1 118 ? 112.713 89.824  146.653 1.00 89.51  ? 118 VAL B CA  1 
ATOM   931  C  C   . VAL A 1 118 ? 113.798 88.774  146.476 1.00 89.51  ? 118 VAL B C   1 
ATOM   932  O  O   . VAL A 1 118 ? 114.780 88.791  147.235 1.00 89.51  ? 118 VAL B O   1 
ATOM   933  C  CB  . VAL A 1 118 ? 112.035 89.647  148.029 1.00 89.51  ? 118 VAL B CB  1 
ATOM   934  C  CG1 . VAL A 1 118 ? 111.101 90.813  148.313 1.00 89.51  ? 118 VAL B CG1 1 
ATOM   935  C  CG2 . VAL A 1 118 ? 111.282 88.328  148.081 1.00 89.51  ? 118 VAL B CG2 1 
ATOM   936  N  N   . ASN A 1 119 ? 113.659 87.860  145.523 1.00 84.73  ? 119 ASN B N   1 
ATOM   937  C  CA  . ASN A 1 119 ? 114.712 86.893  145.253 1.00 84.73  ? 119 ASN B CA  1 
ATOM   938  C  C   . ASN A 1 119 ? 115.969 87.628  144.797 1.00 84.73  ? 119 ASN B C   1 
ATOM   939  O  O   . ASN A 1 119 ? 115.883 88.503  143.924 1.00 84.73  ? 119 ASN B O   1 
ATOM   940  C  CB  . ASN A 1 119 ? 114.251 85.904  144.182 1.00 84.73  ? 119 ASN B CB  1 
ATOM   941  C  CG  . ASN A 1 119 ? 114.933 84.553  144.292 1.00 84.73  ? 119 ASN B CG  1 
ATOM   942  O  OD1 . ASN A 1 119 ? 116.135 84.466  144.534 1.00 84.73  ? 119 ASN B OD1 1 
ATOM   943  N  ND2 . ASN A 1 119 ? 114.162 83.488  144.111 1.00 84.73  ? 119 ASN B ND2 1 
ATOM   944  N  N   . PRO A 1 120 ? 117.140 87.325  145.368 1.00 78.84  ? 120 PRO B N   1 
ATOM   945  C  CA  . PRO A 1 120 ? 118.353 88.078  144.997 1.00 78.84  ? 120 PRO B CA  1 
ATOM   946  C  C   . PRO A 1 120 ? 118.643 88.094  143.505 1.00 78.84  ? 120 PRO B C   1 
ATOM   947  O  O   . PRO A 1 120 ? 119.052 89.135  142.975 1.00 78.84  ? 120 PRO B O   1 
ATOM   948  C  CB  . PRO A 1 120 ? 119.453 87.355  145.783 1.00 78.84  ? 120 PRO B CB  1 
ATOM   949  C  CG  . PRO A 1 120 ? 118.754 86.818  146.982 1.00 78.84  ? 120 PRO B CG  1 
ATOM   950  C  CD  . PRO A 1 120 ? 117.362 86.458  146.539 1.00 78.84  ? 120 PRO B CD  1 
ATOM   951  N  N   . ALA A 1 121 ? 118.435 86.977  142.807 1.00 72.17  ? 121 ALA B N   1 
ATOM   952  C  CA  . ALA A 1 121 ? 118.562 86.990  141.354 1.00 72.17  ? 121 ALA B CA  1 
ATOM   953  C  C   . ALA A 1 121 ? 117.515 87.904  140.730 1.00 72.17  ? 121 ALA B C   1 
ATOM   954  O  O   . ALA A 1 121 ? 117.824 88.725  139.856 1.00 72.17  ? 121 ALA B O   1 
ATOM   955  C  CB  . ALA A 1 121 ? 118.440 85.570  140.803 1.00 72.17  ? 121 ALA B CB  1 
ATOM   956  N  N   . TRP A 1 122 ? 116.267 87.787  141.186 1.00 74.07  ? 122 TRP B N   1 
ATOM   957  C  CA  . TRP A 1 122 ? 115.224 88.679  140.700 1.00 74.07  ? 122 TRP B CA  1 
ATOM   958  C  C   . TRP A 1 122 ? 115.482 90.116  141.127 1.00 74.07  ? 122 TRP B C   1 
ATOM   959  O  O   . TRP A 1 122 ? 115.131 91.047  140.398 1.00 74.07  ? 122 TRP B O   1 
ATOM   960  C  CB  . TRP A 1 122 ? 113.857 88.207  141.190 1.00 74.07  ? 122 TRP B CB  1 
ATOM   961  C  CG  . TRP A 1 122 ? 113.343 87.006  140.454 1.00 74.07  ? 122 TRP B CG  1 
ATOM   962  C  CD1 . TRP A 1 122 ? 113.225 85.737  140.939 1.00 74.07  ? 122 TRP B CD1 1 
ATOM   963  C  CD2 . TRP A 1 122 ? 112.886 86.960  139.097 1.00 74.07  ? 122 TRP B CD2 1 
ATOM   964  N  NE1 . TRP A 1 122 ? 112.719 84.905  139.971 1.00 74.07  ? 122 TRP B NE1 1 
ATOM   965  C  CE2 . TRP A 1 122 ? 112.503 85.632  138.831 1.00 74.07  ? 122 TRP B CE2 1 
ATOM   966  C  CE3 . TRP A 1 122 ? 112.761 87.914  138.084 1.00 74.07  ? 122 TRP B CE3 1 
ATOM   967  C  CZ2 . TRP A 1 122 ? 112.005 85.234  137.594 1.00 74.07  ? 122 TRP B CZ2 1 
ATOM   968  C  CZ3 . TRP A 1 122 ? 112.266 87.517  136.857 1.00 74.07  ? 122 TRP B CZ3 1 
ATOM   969  C  CH2 . TRP A 1 122 ? 111.895 86.189  136.622 1.00 74.07  ? 122 TRP B CH2 1 
ATOM   970  N  N   . LEU A 1 123 ? 116.100 90.320  142.292 1.00 67.85  ? 123 LEU B N   1 
ATOM   971  C  CA  . LEU A 1 123 ? 116.448 91.673  142.713 1.00 67.85  ? 123 LEU B CA  1 
ATOM   972  C  C   . LEU A 1 123 ? 117.483 92.296  141.782 1.00 67.85  ? 123 LEU B C   1 
ATOM   973  O  O   . LEU A 1 123 ? 117.358 93.466  141.399 1.00 67.85  ? 123 LEU B O   1 
ATOM   974  C  CB  . LEU A 1 123 ? 116.959 91.658  144.152 1.00 67.85  ? 123 LEU B CB  1 
ATOM   975  C  CG  . LEU A 1 123 ? 117.118 93.020  144.822 1.00 67.85  ? 123 LEU B CG  1 
ATOM   976  C  CD1 . LEU A 1 123 ? 115.784 93.740  144.867 1.00 67.85  ? 123 LEU B CD1 1 
ATOM   977  C  CD2 . LEU A 1 123 ? 117.688 92.860  146.219 1.00 67.85  ? 123 LEU B CD2 1 
ATOM   978  N  N   . THR A 1 124 ? 118.510 91.530  141.403 1.00 64.55  ? 124 THR B N   1 
ATOM   979  C  CA  . THR A 1 124 ? 119.491 92.042  140.450 1.00 64.55  ? 124 THR B CA  1 
ATOM   980  C  C   . THR A 1 124 ? 118.853 92.297  139.092 1.00 64.55  ? 124 THR B C   1 
ATOM   981  O  O   . THR A 1 124 ? 119.176 93.285  138.422 1.00 64.55  ? 124 THR B O   1 
ATOM   982  C  CB  . THR A 1 124 ? 120.667 91.075  140.313 1.00 64.55  ? 124 THR B CB  1 
ATOM   983  O  OG1 . THR A 1 124 ? 120.196 89.808  139.838 1.00 64.55  ? 124 THR B OG1 1 
ATOM   984  C  CG2 . THR A 1 124 ? 121.367 90.891  141.649 1.00 64.55  ? 124 THR B CG2 1 
ATOM   985  N  N   . LEU A 1 125 ? 117.945 91.414  138.664 1.00 59.48  ? 125 LEU B N   1 
ATOM   986  C  CA  . LEU A 1 125 ? 117.250 91.640  137.400 1.00 59.48  ? 125 LEU B CA  1 
ATOM   987  C  C   . LEU A 1 125 ? 116.421 92.917  137.450 1.00 59.48  ? 125 LEU B C   1 
ATOM   988  O  O   . LEU A 1 125 ? 116.383 93.678  136.477 1.00 59.48  ? 125 LEU B O   1 
ATOM   989  C  CB  . LEU A 1 125 ? 116.368 90.443  137.055 1.00 59.48  ? 125 LEU B CB  1 
ATOM   990  C  CG  . LEU A 1 125 ? 115.678 90.491  135.689 1.00 59.48  ? 125 LEU B CG  1 
ATOM   991  C  CD1 . LEU A 1 125 ? 116.625 90.997  134.611 1.00 59.48  ? 125 LEU B CD1 1 
ATOM   992  C  CD2 . LEU A 1 125 ? 115.129 89.125  135.319 1.00 59.48  ? 125 LEU B CD2 1 
ATOM   993  N  N   . GLY A 1 126 ? 115.748 93.165  138.573 1.00 60.43  ? 126 GLY B N   1 
ATOM   994  C  CA  . GLY A 1 126 ? 114.987 94.395  138.712 1.00 60.43  ? 126 GLY B CA  1 
ATOM   995  C  C   . GLY A 1 126 ? 115.868 95.627  138.702 1.00 60.43  ? 126 GLY B C   1 
ATOM   996  O  O   . GLY A 1 126 ? 115.528 96.639  138.083 1.00 60.43  ? 126 GLY B O   1 
ATOM   997  N  N   . PHE A 1 127 ? 117.013 95.560  139.387 1.00 57.80  ? 127 PHE B N   1 
ATOM   998  C  CA  . PHE A 1 127 ? 117.960 96.671  139.354 1.00 57.80  ? 127 PHE B CA  1 
ATOM   999  C  C   . PHE A 1 127 ? 118.418 96.952  137.929 1.00 57.80  ? 127 PHE B C   1 
ATOM   1000 O  O   . PHE A 1 127 ? 118.438 98.107  137.484 1.00 57.80  ? 127 PHE B O   1 
ATOM   1001 C  CB  . PHE A 1 127 ? 119.163 96.365  140.247 1.00 57.80  ? 127 PHE B CB  1 
ATOM   1002 C  CG  . PHE A 1 127 ? 118.992 96.799  141.671 1.00 57.80  ? 127 PHE B CG  1 
ATOM   1003 C  CD1 . PHE A 1 127 ? 118.832 98.136  141.986 1.00 57.80  ? 127 PHE B CD1 1 
ATOM   1004 C  CD2 . PHE A 1 127 ? 119.009 95.871  142.698 1.00 57.80  ? 127 PHE B CD2 1 
ATOM   1005 C  CE1 . PHE A 1 127 ? 118.678 98.538  143.297 1.00 57.80  ? 127 PHE B CE1 1 
ATOM   1006 C  CE2 . PHE A 1 127 ? 118.858 96.268  144.010 1.00 57.80  ? 127 PHE B CE2 1 
ATOM   1007 C  CZ  . PHE A 1 127 ? 118.693 97.602  144.311 1.00 57.80  ? 127 PHE B CZ  1 
ATOM   1008 N  N   . MET A 1 128 ? 118.780 95.898  137.194 1.00 53.55  ? 128 MET B N   1 
ATOM   1009 C  CA  . MET A 1 128 ? 119.240 96.066  135.821 1.00 53.55  ? 128 MET B CA  1 
ATOM   1010 C  C   . MET A 1 128 ? 118.147 96.650  134.937 1.00 53.55  ? 128 MET B C   1 
ATOM   1011 O  O   . MET A 1 128 ? 118.405 97.559  134.139 1.00 53.55  ? 128 MET B O   1 
ATOM   1012 C  CB  . MET A 1 128 ? 119.715 94.726  135.263 1.00 53.55  ? 128 MET B CB  1 
ATOM   1013 C  CG  . MET A 1 128 ? 120.955 94.190  135.942 1.00 53.55  ? 128 MET B CG  1 
ATOM   1014 S  SD  . MET A 1 128 ? 121.454 92.574  135.332 1.00 53.55  ? 128 MET B SD  1 
ATOM   1015 C  CE  . MET A 1 128 ? 122.037 92.999  133.696 1.00 53.55  ? 128 MET B CE  1 
ATOM   1016 N  N   . SER A 1 129 ? 116.921 96.139  135.063 1.00 54.67  ? 129 SER B N   1 
ATOM   1017 C  CA  . SER A 1 129 ? 115.825 96.626  134.233 1.00 54.67  ? 129 SER B CA  1 
ATOM   1018 C  C   . SER A 1 129 ? 115.518 98.087  134.526 1.00 54.67  ? 129 SER B C   1 
ATOM   1019 O  O   . SER A 1 129 ? 115.333 98.887  133.600 1.00 54.67  ? 129 SER B O   1 
ATOM   1020 C  CB  . SER A 1 129 ? 114.584 95.764  134.448 1.00 54.67  ? 129 SER B CB  1 
ATOM   1021 O  OG  . SER A 1 129 ? 113.489 96.254  133.696 1.00 54.67  ? 129 SER B OG  1 
ATOM   1022 N  N   . SER A 1 130 ? 115.462 98.458  135.807 1.00 52.91  ? 130 SER B N   1 
ATOM   1023 C  CA  . SER A 1 130 ? 115.189 99.847  136.157 1.00 52.91  ? 130 SER B CA  1 
ATOM   1024 C  C   . SER A 1 130 ? 116.294 100.767 135.657 1.00 52.91  ? 130 SER B C   1 
ATOM   1025 O  O   . SER A 1 130 ? 116.015 101.840 135.107 1.00 52.91  ? 130 SER B O   1 
ATOM   1026 C  CB  . SER A 1 130 ? 115.021 99.982  137.669 1.00 52.91  ? 130 SER B CB  1 
ATOM   1027 O  OG  . SER A 1 130 ? 116.201 99.591  138.345 1.00 52.91  ? 130 SER B OG  1 
ATOM   1028 N  N   . THR A 1 131 ? 117.555 100.360 135.828 1.00 52.87  ? 131 THR B N   1 
ATOM   1029 C  CA  . THR A 1 131 ? 118.661 101.192 135.371 1.00 52.87  ? 131 THR B CA  1 
ATOM   1030 C  C   . THR A 1 131 ? 118.637 101.361 133.858 1.00 52.87  ? 131 THR B C   1 
ATOM   1031 O  O   . THR A 1 131 ? 118.858 102.465 133.350 1.00 52.87  ? 131 THR B O   1 
ATOM   1032 C  CB  . THR A 1 131 ? 119.992 100.595 135.823 1.00 52.87  ? 131 THR B CB  1 
ATOM   1033 O  OG1 . THR A 1 131 ? 119.973 100.408 137.242 1.00 52.87  ? 131 THR B OG1 1 
ATOM   1034 C  CG2 . THR A 1 131 ? 121.133 101.523 135.464 1.00 52.87  ? 131 THR B CG2 1 
ATOM   1035 N  N   . ALA A 1 132 ? 118.367 100.281 133.120 1.00 52.03  ? 132 ALA B N   1 
ATOM   1036 C  CA  . ALA A 1 132 ? 118.305 100.381 131.666 1.00 52.03  ? 132 ALA B CA  1 
ATOM   1037 C  C   . ALA A 1 132 ? 117.154 101.273 131.219 1.00 52.03  ? 132 ALA B C   1 
ATOM   1038 O  O   . ALA A 1 132 ? 117.316 102.107 130.318 1.00 52.03  ? 132 ALA B O   1 
ATOM   1039 C  CB  . ALA A 1 132 ? 118.175 98.990  131.049 1.00 52.03  ? 132 ALA B CB  1 
ATOM   1040 N  N   . PHE A 1 133 ? 115.983 101.118 131.841 1.00 50.72  ? 133 PHE B N   1 
ATOM   1041 C  CA  . PHE A 1 133 ? 114.842 101.942 131.460 1.00 50.72  ? 133 PHE B CA  1 
ATOM   1042 C  C   . PHE A 1 133 ? 115.116 103.415 131.728 1.00 50.72  ? 133 PHE B C   1 
ATOM   1043 O  O   . PHE A 1 133 ? 114.771 104.275 130.910 1.00 50.72  ? 133 PHE B O   1 
ATOM   1044 C  CB  . PHE A 1 133 ? 113.589 101.485 132.201 1.00 50.72  ? 133 PHE B CB  1 
ATOM   1045 C  CG  . PHE A 1 133 ? 112.342 102.199 131.771 1.00 50.72  ? 133 PHE B CG  1 
ATOM   1046 C  CD1 . PHE A 1 133 ? 111.635 101.774 130.662 1.00 50.72  ? 133 PHE B CD1 1 
ATOM   1047 C  CD2 . PHE A 1 133 ? 111.882 103.300 132.471 1.00 50.72  ? 133 PHE B CD2 1 
ATOM   1048 C  CE1 . PHE A 1 133 ? 110.492 102.430 130.262 1.00 50.72  ? 133 PHE B CE1 1 
ATOM   1049 C  CE2 . PHE A 1 133 ? 110.740 103.960 132.075 1.00 50.72  ? 133 PHE B CE2 1 
ATOM   1050 C  CZ  . PHE A 1 133 ? 110.044 103.525 130.970 1.00 50.72  ? 133 PHE B CZ  1 
ATOM   1051 N  N   . LEU A 1 134 ? 115.732 103.728 132.869 1.00 52.15  ? 134 LEU B N   1 
ATOM   1052 C  CA  . LEU A 1 134 ? 116.061 105.120 133.159 1.00 52.15  ? 134 LEU B CA  1 
ATOM   1053 C  C   . LEU A 1 134 ? 117.123 105.652 132.204 1.00 52.15  ? 134 LEU B C   1 
ATOM   1054 O  O   . LEU A 1 134 ? 117.028 106.792 131.736 1.00 52.15  ? 134 LEU B O   1 
ATOM   1055 C  CB  . LEU A 1 134 ? 116.519 105.262 134.608 1.00 52.15  ? 134 LEU B CB  1 
ATOM   1056 C  CG  . LEU A 1 134 ? 115.454 104.932 135.650 1.00 52.15  ? 134 LEU B CG  1 
ATOM   1057 C  CD1 . LEU A 1 134 ? 116.037 104.987 137.049 1.00 52.15  ? 134 LEU B CD1 1 
ATOM   1058 C  CD2 . LEU A 1 134 ? 114.278 105.880 135.512 1.00 52.15  ? 134 LEU B CD2 1 
ATOM   1059 N  N   . SER A 1 135 ? 118.140 104.843 131.896 1.00 50.76  ? 135 SER B N   1 
ATOM   1060 C  CA  . SER A 1 135 ? 119.205 105.274 131.001 1.00 50.76  ? 135 SER B CA  1 
ATOM   1061 C  C   . SER A 1 135 ? 118.750 105.392 129.555 1.00 50.76  ? 135 SER B C   1 
ATOM   1062 O  O   . SER A 1 135 ? 119.470 105.989 128.748 1.00 50.76  ? 135 SER B O   1 
ATOM   1063 C  CB  . SER A 1 135 ? 120.385 104.309 131.089 1.00 50.76  ? 135 SER B CB  1 
ATOM   1064 O  OG  . SER A 1 135 ? 121.371 104.631 130.125 1.00 50.76  ? 135 SER B OG  1 
ATOM   1065 N  N   . MET A 1 136 ? 117.594 104.824 129.206 1.00 48.82  ? 136 MET B N   1 
ATOM   1066 C  CA  . MET A 1 136 ? 117.057 105.030 127.864 1.00 48.82  ? 136 MET B CA  1 
ATOM   1067 C  C   . MET A 1 136 ? 116.846 106.512 127.577 1.00 48.82  ? 136 MET B C   1 
ATOM   1068 O  O   . MET A 1 136 ? 117.146 106.987 126.475 1.00 48.82  ? 136 MET B O   1 
ATOM   1069 C  CB  . MET A 1 136 ? 115.745 104.266 127.695 1.00 48.82  ? 136 MET B CB  1 
ATOM   1070 C  CG  . MET A 1 136 ? 115.916 102.801 127.354 1.00 48.82  ? 136 MET B CG  1 
ATOM   1071 S  SD  . MET A 1 136 ? 114.519 102.143 126.429 1.00 48.82  ? 136 MET B SD  1 
ATOM   1072 C  CE  . MET A 1 136 ? 113.154 102.929 127.277 1.00 48.82  ? 136 MET B CE  1 
ATOM   1073 N  N   . TRP A 1 137 ? 116.334 107.260 128.554 1.00 51.06  ? 137 TRP B N   1 
ATOM   1074 C  CA  . TRP A 1 137 ? 116.072 108.687 128.402 1.00 51.06  ? 137 TRP B CA  1 
ATOM   1075 C  C   . TRP A 1 137 ? 117.142 109.554 129.053 1.00 51.06  ? 137 TRP B C   1 
ATOM   1076 O  O   . TRP A 1 137 ? 117.675 110.466 128.414 1.00 51.06  ? 137 TRP B O   1 
ATOM   1077 C  CB  . TRP A 1 137 ? 114.697 109.030 128.984 1.00 51.06  ? 137 TRP B CB  1 
ATOM   1078 C  CG  . TRP A 1 137 ? 113.660 108.007 128.668 1.00 51.06  ? 137 TRP B CG  1 
ATOM   1079 C  CD1 . TRP A 1 137 ? 113.188 107.037 129.500 1.00 51.06  ? 137 TRP B CD1 1 
ATOM   1080 C  CD2 . TRP A 1 137 ? 112.969 107.843 127.426 1.00 51.06  ? 137 TRP B CD2 1 
ATOM   1081 N  NE1 . TRP A 1 137 ? 112.243 106.279 128.854 1.00 51.06  ? 137 TRP B NE1 1 
ATOM   1082 C  CE2 . TRP A 1 137 ? 112.090 106.755 127.579 1.00 51.06  ? 137 TRP B CE2 1 
ATOM   1083 C  CE3 . TRP A 1 137 ? 113.007 108.513 126.200 1.00 51.06  ? 137 TRP B CE3 1 
ATOM   1084 C  CZ2 . TRP A 1 137 ? 111.257 106.320 126.553 1.00 51.06  ? 137 TRP B CZ2 1 
ATOM   1085 C  CZ3 . TRP A 1 137 ? 112.179 108.079 125.183 1.00 51.06  ? 137 TRP B CZ3 1 
ATOM   1086 C  CH2 . TRP A 1 137 ? 111.316 106.994 125.365 1.00 51.06  ? 137 TRP B CH2 1 
ATOM   1087 N  N   . LEU A 1 138 ? 117.468 109.290 130.315 1.00 51.17  ? 138 LEU B N   1 
ATOM   1088 C  CA  . LEU A 1 138 ? 118.501 110.047 131.004 1.00 51.17  ? 138 LEU B CA  1 
ATOM   1089 C  C   . LEU A 1 138 ? 119.876 109.689 130.441 1.00 51.17  ? 138 LEU B C   1 
ATOM   1090 O  O   . LEU A 1 138 ? 120.018 108.859 129.541 1.00 51.17  ? 138 LEU B O   1 
ATOM   1091 C  CB  . LEU A 1 138 ? 118.440 109.779 132.506 1.00 51.17  ? 138 LEU B CB  1 
ATOM   1092 C  CG  . LEU A 1 138 ? 117.365 110.515 133.308 1.00 51.17  ? 138 LEU B CG  1 
ATOM   1093 C  CD1 . LEU A 1 138 ? 116.953 109.700 134.521 1.00 51.17  ? 138 LEU B CD1 1 
ATOM   1094 C  CD2 . LEU A 1 138 ? 117.861 111.886 133.731 1.00 51.17  ? 138 LEU B CD2 1 
ATOM   1095 N  N   . SER A 1 139 ? 120.906 110.331 130.980 1.00 53.05  ? 139 SER B N   1 
ATOM   1096 C  CA  . SER A 1 139 ? 122.276 110.041 130.590 1.00 53.05  ? 139 SER B CA  1 
ATOM   1097 C  C   . SER A 1 139 ? 122.822 108.885 131.416 1.00 53.05  ? 139 SER B C   1 
ATOM   1098 O  O   . SER A 1 139 ? 122.389 108.646 132.545 1.00 53.05  ? 139 SER B O   1 
ATOM   1099 C  CB  . SER A 1 139 ? 123.163 111.274 130.764 1.00 53.05  ? 139 SER B CB  1 
ATOM   1100 O  OG  . SER A 1 139 ? 124.392 111.115 130.078 1.00 53.05  ? 139 SER B OG  1 
ATOM   1101 N  N   . ASN A 1 140 ? 123.784 108.162 130.835 1.00 53.63  ? 140 ASN B N   1 
ATOM   1102 C  CA  . ASN A 1 140 ? 124.365 107.014 131.525 1.00 53.63  ? 140 ASN B CA  1 
ATOM   1103 C  C   . ASN A 1 140 ? 125.036 107.433 132.826 1.00 53.63  ? 140 ASN B C   1 
ATOM   1104 O  O   . ASN A 1 140 ? 124.856 106.784 133.865 1.00 53.63  ? 140 ASN B O   1 
ATOM   1105 C  CB  . ASN A 1 140 ? 125.371 106.312 130.613 1.00 53.63  ? 140 ASN B CB  1 
ATOM   1106 C  CG  . ASN A 1 140 ? 124.712 105.622 129.439 1.00 53.63  ? 140 ASN B CG  1 
ATOM   1107 O  OD1 . ASN A 1 140 ? 123.509 105.751 129.223 1.00 53.63  ? 140 ASN B OD1 1 
ATOM   1108 N  ND2 . ASN A 1 140 ? 125.501 104.886 128.668 1.00 53.63  ? 140 ASN B ND2 1 
ATOM   1109 N  N   . THR A 1 141 ? 125.806 108.521 132.788 1.00 56.11  ? 141 THR B N   1 
ATOM   1110 C  CA  . THR A 1 141 ? 126.524 108.980 133.973 1.00 56.11  ? 141 THR B CA  1 
ATOM   1111 C  C   . THR A 1 141 ? 125.561 109.332 135.099 1.00 56.11  ? 141 THR B C   1 
ATOM   1112 O  O   . THR A 1 141 ? 125.713 108.863 136.233 1.00 56.11  ? 141 THR B O   1 
ATOM   1113 C  CB  . THR A 1 141 ? 127.392 110.185 133.612 1.00 56.11  ? 141 THR B CB  1 
ATOM   1114 O  OG1 . THR A 1 141 ? 128.367 109.799 132.637 1.00 56.11  ? 141 THR B OG1 1 
ATOM   1115 C  CG2 . THR A 1 141 ? 128.093 110.730 134.839 1.00 56.11  ? 141 THR B CG2 1 
ATOM   1116 N  N   . SER A 1 142 ? 124.556 110.160 134.799 1.00 57.21  ? 142 SER B N   1 
ATOM   1117 C  CA  . SER A 1 142 ? 123.600 110.569 135.822 1.00 57.21  ? 142 SER B CA  1 
ATOM   1118 C  C   . SER A 1 142 ? 122.791 109.383 136.328 1.00 57.21  ? 142 SER B C   1 
ATOM   1119 O  O   . SER A 1 142 ? 122.544 109.261 137.534 1.00 57.21  ? 142 SER B O   1 
ATOM   1120 C  CB  . SER A 1 142 ? 122.674 111.651 135.269 1.00 57.21  ? 142 SER B CB  1 
ATOM   1121 O  OG  . SER A 1 142 ? 123.415 112.678 134.636 1.00 57.21  ? 142 SER B OG  1 
ATOM   1122 N  N   . THR A 1 143 ? 122.371 108.497 135.422 1.00 54.71  ? 143 THR B N   1 
ATOM   1123 C  CA  . THR A 1 143 ? 121.591 107.336 135.833 1.00 54.71  ? 143 THR B CA  1 
ATOM   1124 C  C   . THR A 1 143 ? 122.380 106.450 136.785 1.00 54.71  ? 143 THR B C   1 
ATOM   1125 O  O   . THR A 1 143 ? 121.862 106.034 137.827 1.00 54.71  ? 143 THR B O   1 
ATOM   1126 C  CB  . THR A 1 143 ? 121.148 106.537 134.610 1.00 54.71  ? 143 THR B CB  1 
ATOM   1127 O  OG1 . THR A 1 143 ? 120.390 107.382 133.737 1.00 54.71  ? 143 THR B OG1 1 
ATOM   1128 C  CG2 . THR A 1 143 ? 120.291 105.360 135.029 1.00 54.71  ? 143 THR B CG2 1 
ATOM   1129 N  N   . ALA A 1 144 ? 123.639 106.155 136.451 1.00 59.17  ? 144 ALA B N   1 
ATOM   1130 C  CA  . ALA A 1 144 ? 124.453 105.330 137.338 1.00 59.17  ? 144 ALA B CA  1 
ATOM   1131 C  C   . ALA A 1 144 ? 124.707 106.029 138.668 1.00 59.17  ? 144 ALA B C   1 
ATOM   1132 O  O   . ALA A 1 144 ? 124.571 105.414 139.734 1.00 59.17  ? 144 ALA B O   1 
ATOM   1133 C  CB  . ALA A 1 144 ? 125.773 104.971 136.659 1.00 59.17  ? 144 ALA B CB  1 
ATOM   1134 N  N   . ALA A 1 145 ? 125.063 107.318 138.628 1.00 60.74  ? 145 ALA B N   1 
ATOM   1135 C  CA  . ALA A 1 145 ? 125.370 108.047 139.852 1.00 60.74  ? 145 ALA B CA  1 
ATOM   1136 C  C   . ALA A 1 145 ? 124.154 108.214 140.750 1.00 60.74  ? 145 ALA B C   1 
ATOM   1137 O  O   . ALA A 1 145 ? 124.316 108.407 141.959 1.00 60.74  ? 145 ALA B O   1 
ATOM   1138 C  CB  . ALA A 1 145 ? 125.955 109.418 139.514 1.00 60.74  ? 145 ALA B CB  1 
ATOM   1139 N  N   . MET A 1 146 ? 122.947 108.153 140.192 1.00 63.69  ? 146 MET B N   1 
ATOM   1140 C  CA  . MET A 1 146 ? 121.741 108.222 141.004 1.00 63.69  ? 146 MET B CA  1 
ATOM   1141 C  C   . MET A 1 146 ? 121.336 106.851 141.535 1.00 63.69  ? 146 MET B C   1 
ATOM   1142 O  O   . MET A 1 146 ? 120.962 106.723 142.705 1.00 63.69  ? 146 MET B O   1 
ATOM   1143 C  CB  . MET A 1 146 ? 120.600 108.837 140.188 1.00 63.69  ? 146 MET B CB  1 
ATOM   1144 C  CG  . MET A 1 146 ? 119.228 108.738 140.834 1.00 63.69  ? 146 MET B CG  1 
ATOM   1145 S  SD  . MET A 1 146 ? 118.310 107.272 140.322 1.00 63.69  ? 146 MET B SD  1 
ATOM   1146 C  CE  . MET A 1 146 ? 118.187 107.554 138.560 1.00 63.69  ? 146 MET B CE  1 
ATOM   1147 N  N   . VAL A 1 147 ? 121.403 105.820 140.690 1.00 61.47  ? 147 VAL B N   1 
ATOM   1148 C  CA  . VAL A 1 147 ? 120.946 104.497 141.098 1.00 61.47  ? 147 VAL B CA  1 
ATOM   1149 C  C   . VAL A 1 147 ? 121.889 103.870 142.118 1.00 61.47  ? 147 VAL B C   1 
ATOM   1150 O  O   . VAL A 1 147 ? 121.436 103.183 143.042 1.00 61.47  ? 147 VAL B O   1 
ATOM   1151 C  CB  . VAL A 1 147 ? 120.760 103.595 139.864 1.00 61.47  ? 147 VAL B CB  1 
ATOM   1152 C  CG1 . VAL A 1 147 ? 120.448 102.174 140.284 1.00 61.47  ? 147 VAL B CG1 1 
ATOM   1153 C  CG2 . VAL A 1 147 ? 119.643 104.131 138.991 1.00 61.47  ? 147 VAL B CG2 1 
ATOM   1154 N  N   . MET A 1 148 ? 123.201 104.086 141.983 1.00 65.55  ? 148 MET B N   1 
ATOM   1155 C  CA  . MET A 1 148 ? 124.153 103.386 142.846 1.00 65.55  ? 148 MET B CA  1 
ATOM   1156 C  C   . MET A 1 148 ? 123.928 103.607 144.339 1.00 65.55  ? 148 MET B C   1 
ATOM   1157 O  O   . MET A 1 148 ? 123.982 102.619 145.092 1.00 65.55  ? 148 MET B O   1 
ATOM   1158 C  CB  . MET A 1 148 ? 125.584 103.753 142.445 1.00 65.55  ? 148 MET B CB  1 
ATOM   1159 C  CG  . MET A 1 148 ? 126.631 103.044 143.284 1.00 65.55  ? 148 MET B CG  1 
ATOM   1160 S  SD  . MET A 1 148 ? 126.438 101.254 143.274 1.00 65.55  ? 148 MET B SD  1 
ATOM   1161 C  CE  . MET A 1 148 ? 127.394 100.820 141.833 1.00 65.55  ? 148 MET B CE  1 
ATOM   1162 N  N   . PRO A 1 149 ? 123.713 104.830 144.844 1.00 67.57  ? 149 PRO B N   1 
ATOM   1163 C  CA  . PRO A 1 149 ? 123.476 104.966 146.293 1.00 67.57  ? 149 PRO B CA  1 
ATOM   1164 C  C   . PRO A 1 149 ? 122.282 104.170 146.790 1.00 67.57  ? 149 PRO B C   1 
ATOM   1165 O  O   . PRO A 1 149 ? 122.335 103.587 147.883 1.00 67.57  ? 149 PRO B O   1 
ATOM   1166 C  CB  . PRO A 1 149 ? 123.265 106.475 146.469 1.00 67.57  ? 149 PRO B CB  1 
ATOM   1167 C  CG  . PRO A 1 149 ? 124.001 107.085 145.339 1.00 67.57  ? 149 PRO B CG  1 
ATOM   1168 C  CD  . PRO A 1 149 ? 123.810 106.147 144.189 1.00 67.57  ? 149 PRO B CD  1 
ATOM   1169 N  N   . ILE A 1 150 ? 121.204 104.118 146.004 1.00 68.75  ? 150 ILE B N   1 
ATOM   1170 C  CA  . ILE A 1 150 ? 120.017 103.374 146.414 1.00 68.75  ? 150 ILE B CA  1 
ATOM   1171 C  C   . ILE A 1 150 ? 120.342 101.893 146.550 1.00 68.75  ? 150 ILE B C   1 
ATOM   1172 O  O   . ILE A 1 150 ? 119.993 101.251 147.546 1.00 68.75  ? 150 ILE B O   1 
ATOM   1173 C  CB  . ILE A 1 150 ? 118.867 103.608 145.419 1.00 68.75  ? 150 ILE B CB  1 
ATOM   1174 C  CG1 . ILE A 1 150 ? 118.404 105.065 145.470 1.00 68.75  ? 150 ILE B CG1 1 
ATOM   1175 C  CG2 . ILE A 1 150 ? 117.713 102.669 145.711 1.00 68.75  ? 150 ILE B CG2 1 
ATOM   1176 C  CD1 . ILE A 1 150 ? 117.729 105.532 144.201 1.00 68.75  ? 150 ILE B CD1 1 
ATOM   1177 N  N   . ALA A 1 151 ? 121.029 101.332 145.553 1.00 73.85  ? 151 ALA B N   1 
ATOM   1178 C  CA  . ALA A 1 151 ? 121.383 99.918  145.607 1.00 73.85  ? 151 ALA B CA  1 
ATOM   1179 C  C   . ALA A 1 151 ? 122.358 99.634  146.739 1.00 73.85  ? 151 ALA B C   1 
ATOM   1180 O  O   . ALA A 1 151 ? 122.295 98.574  147.370 1.00 73.85  ? 151 ALA B O   1 
ATOM   1181 C  CB  . ALA A 1 151 ? 121.972 99.470  144.274 1.00 73.85  ? 151 ALA B CB  1 
ATOM   1182 N  N   . GLU A 1 152 ? 123.284 100.560 146.995 1.00 81.49  ? 152 GLU B N   1 
ATOM   1183 C  CA  . GLU A 1 152 ? 124.212 100.381 148.106 1.00 81.49  ? 152 GLU B CA  1 
ATOM   1184 C  C   . GLU A 1 152 ? 123.466 100.326 149.432 1.00 81.49  ? 152 GLU B C   1 
ATOM   1185 O  O   . GLU A 1 152 ? 123.751 99.472  150.280 1.00 81.49  ? 152 GLU B O   1 
ATOM   1186 C  CB  . GLU A 1 152 ? 125.247 101.506 148.111 1.00 81.49  ? 152 GLU B CB  1 
ATOM   1187 C  CG  . GLU A 1 152 ? 126.354 101.327 149.133 1.00 81.49  ? 152 GLU B CG  1 
ATOM   1188 C  CD  . GLU A 1 152 ? 127.288 100.185 148.784 1.00 81.49  ? 152 GLU B CD  1 
ATOM   1189 O  OE1 . GLU A 1 152 ? 127.413 99.863  147.584 1.00 81.49  ? 152 GLU B OE1 1 
ATOM   1190 O  OE2 . GLU A 1 152 ? 127.898 99.611  149.710 1.00 81.49  ? 152 GLU B OE2 1 
ATOM   1191 N  N   . ALA A 1 153 ? 122.491 101.217 149.622 1.00 82.90  ? 153 ALA B N   1 
ATOM   1192 C  CA  . ALA A 1 153 ? 121.672 101.165 150.829 1.00 82.90  ? 153 ALA B CA  1 
ATOM   1193 C  C   . ALA A 1 153 ? 120.893 99.855  150.905 1.00 82.90  ? 153 ALA B C   1 
ATOM   1194 O  O   . ALA A 1 153 ? 120.801 99.230  151.969 1.00 82.90  ? 153 ALA B O   1 
ATOM   1195 C  CB  . ALA A 1 153 ? 120.725 102.363 150.870 1.00 82.90  ? 153 ALA B CB  1 
ATOM   1196 N  N   . VAL A 1 154 ? 120.327 99.421  149.778 1.00 84.10  ? 154 VAL B N   1 
ATOM   1197 C  CA  . VAL A 1 154 ? 119.540 98.192  149.778 1.00 84.10  ? 154 VAL B CA  1 
ATOM   1198 C  C   . VAL A 1 154 ? 120.398 97.002  150.181 1.00 84.10  ? 154 VAL B C   1 
ATOM   1199 O  O   . VAL A 1 154 ? 119.990 96.186  151.015 1.00 84.10  ? 154 VAL B O   1 
ATOM   1200 C  CB  . VAL A 1 154 ? 118.880 97.969  148.408 1.00 84.10  ? 154 VAL B CB  1 
ATOM   1201 C  CG1 . VAL A 1 154 ? 118.181 96.625  148.383 1.00 84.10  ? 154 VAL B CG1 1 
ATOM   1202 C  CG2 . VAL A 1 154 ? 117.888 99.073  148.119 1.00 84.10  ? 154 VAL B CG2 1 
ATOM   1203 N  N   . VAL A 1 155 ? 121.597 96.882  149.608 1.00 88.62  ? 155 VAL B N   1 
ATOM   1204 C  CA  . VAL A 1 155 ? 122.445 95.739  149.934 1.00 88.62  ? 155 VAL B CA  1 
ATOM   1205 C  C   . VAL A 1 155 ? 122.957 95.839  151.368 1.00 88.62  ? 155 VAL B C   1 
ATOM   1206 O  O   . VAL A 1 155 ? 123.071 94.825  152.069 1.00 88.62  ? 155 VAL B O   1 
ATOM   1207 C  CB  . VAL A 1 155 ? 123.591 95.586  148.916 1.00 88.62  ? 155 VAL B CB  1 
ATOM   1208 C  CG1 . VAL A 1 155 ? 123.032 95.329  147.525 1.00 88.62  ? 155 VAL B CG1 1 
ATOM   1209 C  CG2 . VAL A 1 155 ? 124.502 96.798  148.914 1.00 88.62  ? 155 VAL B CG2 1 
ATOM   1210 N  N   . GLN A 1 156 ? 123.258 97.055  151.838 1.00 94.68  ? 156 GLN B N   1 
ATOM   1211 C  CA  . GLN A 1 156 ? 123.750 97.207  153.203 1.00 94.68  ? 156 GLN B CA  1 
ATOM   1212 C  C   . GLN A 1 156 ? 122.703 96.777  154.222 1.00 94.68  ? 156 GLN B C   1 
ATOM   1213 O  O   . GLN A 1 156 ? 123.019 96.069  155.185 1.00 94.68  ? 156 GLN B O   1 
ATOM   1214 C  CB  . GLN A 1 156 ? 124.180 98.653  153.449 1.00 94.68  ? 156 GLN B CB  1 
ATOM   1215 C  CG  . GLN A 1 156 ? 125.187 98.832  154.581 1.00 94.68  ? 156 GLN B CG  1 
ATOM   1216 C  CD  . GLN A 1 156 ? 126.164 97.673  154.711 1.00 94.68  ? 156 GLN B CD  1 
ATOM   1217 O  OE1 . GLN A 1 156 ? 126.781 97.246  153.733 1.00 94.68  ? 156 GLN B OE1 1 
ATOM   1218 N  NE2 . GLN A 1 156 ? 126.306 97.158  155.926 1.00 94.68  ? 156 GLN B NE2 1 
ATOM   1219 N  N   . GLN A 1 157 ? 121.449 97.191  154.031 1.00 94.03  ? 157 GLN B N   1 
ATOM   1220 C  CA  . GLN A 1 157 ? 120.393 96.773  154.948 1.00 94.03  ? 157 GLN B CA  1 
ATOM   1221 C  C   . GLN A 1 157 ? 119.898 95.347  154.725 1.00 94.03  ? 157 GLN B C   1 
ATOM   1222 O  O   . GLN A 1 157 ? 119.384 94.742  155.672 1.00 94.03  ? 157 GLN B O   1 
ATOM   1223 C  CB  . GLN A 1 157 ? 119.225 97.763  154.901 1.00 94.03  ? 157 GLN B CB  1 
ATOM   1224 C  CG  . GLN A 1 157 ? 119.458 99.060  155.687 1.00 94.03  ? 157 GLN B CG  1 
ATOM   1225 C  CD  . GLN A 1 157 ? 120.235 100.123 154.943 1.00 94.03  ? 157 GLN B CD  1 
ATOM   1226 O  OE1 . GLN A 1 157 ? 121.303 99.858  154.397 1.00 94.03  ? 157 GLN B OE1 1 
ATOM   1227 N  NE2 . GLN A 1 157 ? 119.699 101.338 154.917 1.00 94.03  ? 157 GLN B NE2 1 
ATOM   1228 N  N   . ILE A 1 158 ? 120.026 94.784  153.520 1.00 97.07  ? 158 ILE B N   1 
ATOM   1229 C  CA  . ILE A 1 158 ? 119.652 93.381  153.365 1.00 97.07  ? 158 ILE B CA  1 
ATOM   1230 C  C   . ILE A 1 158 ? 120.698 92.478  154.009 1.00 97.07  ? 158 ILE B C   1 
ATOM   1231 O  O   . ILE A 1 158 ? 120.360 91.427  154.567 1.00 97.07  ? 158 ILE B O   1 
ATOM   1232 C  CB  . ILE A 1 158 ? 119.419 93.014  151.885 1.00 97.07  ? 158 ILE B CB  1 
ATOM   1233 C  CG1 . ILE A 1 158 ? 118.782 91.630  151.773 1.00 97.07  ? 158 ILE B CG1 1 
ATOM   1234 C  CG2 . ILE A 1 158 ? 120.709 92.989  151.109 1.00 97.07  ? 158 ILE B CG2 1 
ATOM   1235 C  CD1 . ILE A 1 158 ? 118.234 91.327  150.398 1.00 97.07  ? 158 ILE B CD1 1 
ATOM   1236 N  N   . ILE A 1 159 ? 121.976 92.864  153.954 1.00 98.71  ? 159 ILE B N   1 
ATOM   1237 C  CA  . ILE A 1 159 ? 123.009 92.047  154.580 1.00 98.71  ? 159 ILE B CA  1 
ATOM   1238 C  C   . ILE A 1 159 ? 123.094 92.304  156.079 1.00 98.71  ? 159 ILE B C   1 
ATOM   1239 O  O   . ILE A 1 159 ? 123.661 91.484  156.811 1.00 98.71  ? 159 ILE B O   1 
ATOM   1240 C  CB  . ILE A 1 159 ? 124.372 92.282  153.907 1.00 98.71  ? 159 ILE B CB  1 
ATOM   1241 C  CG1 . ILE A 1 159 ? 125.328 91.130  154.221 1.00 98.71  ? 159 ILE B CG1 1 
ATOM   1242 C  CG2 . ILE A 1 159 ? 124.976 93.600  154.361 1.00 98.71  ? 159 ILE B CG2 1 
ATOM   1243 C  CD1 . ILE A 1 159 ? 124.875 89.800  153.666 1.00 98.71  ? 159 ILE B CD1 1 
ATOM   1244 N  N   . ASN A 1 160 ? 122.530 93.413  156.561 1.00 101.52 ? 160 ASN B N   1 
ATOM   1245 C  CA  . ASN A 1 160 ? 122.510 93.684  157.993 1.00 101.52 ? 160 ASN B CA  1 
ATOM   1246 C  C   . ASN A 1 160 ? 121.563 92.766  158.751 1.00 101.52 ? 160 ASN B C   1 
ATOM   1247 O  O   . ASN A 1 160 ? 121.607 92.744  159.986 1.00 101.52 ? 160 ASN B O   1 
ATOM   1248 C  CB  . ASN A 1 160 ? 122.128 95.143  158.246 1.00 101.52 ? 160 ASN B CB  1 
ATOM   1249 C  CG  . ASN A 1 160 ? 123.328 96.067  158.241 1.00 101.52 ? 160 ASN B CG  1 
ATOM   1250 O  OD1 . ASN A 1 160 ? 124.473 95.616  158.273 1.00 101.52 ? 160 ASN B OD1 1 
ATOM   1251 N  ND2 . ASN A 1 160 ? 123.073 97.369  158.201 1.00 101.52 ? 160 ASN B ND2 1 
ATOM   1252 N  N   . ALA A 1 161 ? 120.715 92.017  158.053 1.00 102.75 ? 161 ALA B N   1 
ATOM   1253 C  CA  . ALA A 1 161 ? 119.794 91.093  158.700 1.00 102.75 ? 161 ALA B CA  1 
ATOM   1254 C  C   . ALA A 1 161 ? 120.260 89.653  158.517 1.00 102.75 ? 161 ALA B C   1 
ATOM   1255 O  O   . ALA A 1 161 ? 121.423 89.403  158.202 1.00 102.75 ? 161 ALA B O   1 
ATOM   1256 C  CB  . ALA A 1 161 ? 118.388 91.273  158.151 1.00 102.75 ? 161 ALA B CB  1 
ATOM   1257 N  N   . THR A 1 230 ? 131.189 87.576  156.517 1.00 98.51  ? 230 THR B N   1 
ATOM   1258 C  CA  . THR A 1 230 ? 130.168 87.214  155.540 1.00 98.51  ? 230 THR B CA  1 
ATOM   1259 C  C   . THR A 1 230 ? 130.572 87.656  154.138 1.00 98.51  ? 230 THR B C   1 
ATOM   1260 O  O   . THR A 1 230 ? 130.255 88.767  153.713 1.00 98.51  ? 230 THR B O   1 
ATOM   1261 C  CB  . THR A 1 230 ? 128.805 87.837  155.889 1.00 98.51  ? 230 THR B CB  1 
ATOM   1262 O  OG1 . THR A 1 230 ? 128.932 89.263  155.952 1.00 98.51  ? 230 THR B OG1 1 
ATOM   1263 C  CG2 . THR A 1 230 ? 128.312 87.319  157.230 1.00 98.51  ? 230 THR B CG2 1 
ATOM   1264 N  N   . LYS A 1 231 ? 131.276 86.778  153.420 1.00 96.55  ? 231 LYS B N   1 
ATOM   1265 C  CA  . LYS A 1 231 ? 131.695 87.097  152.061 1.00 96.55  ? 231 LYS B CA  1 
ATOM   1266 C  C   . LYS A 1 231 ? 130.526 87.117  151.086 1.00 96.55  ? 231 LYS B C   1 
ATOM   1267 O  O   . LYS A 1 231 ? 130.673 87.638  149.974 1.00 96.55  ? 231 LYS B O   1 
ATOM   1268 C  CB  . LYS A 1 231 ? 132.764 86.102  151.595 1.00 96.55  ? 231 LYS B CB  1 
ATOM   1269 C  CG  . LYS A 1 231 ? 132.307 84.648  151.519 1.00 96.55  ? 231 LYS B CG  1 
ATOM   1270 C  CD  . LYS A 1 231 ? 131.883 84.256  150.108 1.00 96.55  ? 231 LYS B CD  1 
ATOM   1271 C  CE  . LYS A 1 231 ? 131.551 82.775  150.020 1.00 96.55  ? 231 LYS B CE  1 
ATOM   1272 N  NZ  . LYS A 1 231 ? 131.133 82.381  148.647 1.00 96.55  ? 231 LYS B NZ  1 
ATOM   1273 N  N   . LYS A 1 232 ? 129.375 86.562  151.475 1.00 95.12  ? 232 LYS B N   1 
ATOM   1274 C  CA  . LYS A 1 232 ? 128.206 86.593  150.603 1.00 95.12  ? 232 LYS B CA  1 
ATOM   1275 C  C   . LYS A 1 232 ? 127.757 88.024  150.339 1.00 95.12  ? 232 LYS B C   1 
ATOM   1276 O  O   . LYS A 1 232 ? 127.387 88.367  149.210 1.00 95.12  ? 232 LYS B O   1 
ATOM   1277 C  CB  . LYS A 1 232 ? 127.069 85.777  151.218 1.00 95.12  ? 232 LYS B CB  1 
ATOM   1278 C  CG  . LYS A 1 232 ? 127.391 84.303  151.390 1.00 95.12  ? 232 LYS B CG  1 
ATOM   1279 C  CD  . LYS A 1 232 ? 127.842 83.679  150.079 1.00 95.12  ? 232 LYS B CD  1 
ATOM   1280 C  CE  . LYS A 1 232 ? 126.715 83.658  149.058 1.00 95.12  ? 232 LYS B CE  1 
ATOM   1281 N  NZ  . LYS A 1 232 ? 125.458 83.106  149.633 1.00 95.12  ? 232 LYS B NZ  1 
ATOM   1282 N  N   . GLY A 1 233 ? 127.780 88.872  151.368 1.00 91.11  ? 233 GLY B N   1 
ATOM   1283 C  CA  . GLY A 1 233 ? 127.448 90.272  151.163 1.00 91.11  ? 233 GLY B CA  1 
ATOM   1284 C  C   . GLY A 1 233 ? 128.413 90.964  150.222 1.00 91.11  ? 233 GLY B C   1 
ATOM   1285 O  O   . GLY A 1 233 ? 128.002 91.749  149.365 1.00 91.11  ? 233 GLY B O   1 
ATOM   1286 N  N   . HIS A 1 234 ? 129.708 90.674  150.361 1.00 88.86  ? 234 HIS B N   1 
ATOM   1287 C  CA  . HIS A 1 234 ? 130.708 91.255  149.469 1.00 88.86  ? 234 HIS B CA  1 
ATOM   1288 C  C   . HIS A 1 234 ? 130.469 90.826  148.026 1.00 88.86  ? 234 HIS B C   1 
ATOM   1289 O  O   . HIS A 1 234 ? 130.506 91.650  147.102 1.00 88.86  ? 234 HIS B O   1 
ATOM   1290 C  CB  . HIS A 1 234 ? 132.106 90.848  149.938 1.00 88.86  ? 234 HIS B CB  1 
ATOM   1291 C  CG  . HIS A 1 234 ? 133.214 91.343  149.061 1.00 88.86  ? 234 HIS B CG  1 
ATOM   1292 N  ND1 . HIS A 1 234 ? 133.538 92.678  148.951 1.00 88.86  ? 234 HIS B ND1 1 
ATOM   1293 C  CD2 . HIS A 1 234 ? 134.085 90.678  148.266 1.00 88.86  ? 234 HIS B CD2 1 
ATOM   1294 C  CE1 . HIS A 1 234 ? 134.555 92.815  148.119 1.00 88.86  ? 234 HIS B CE1 1 
ATOM   1295 N  NE2 . HIS A 1 234 ? 134.907 91.617  147.691 1.00 88.86  ? 234 HIS B NE2 1 
ATOM   1296 N  N   . VAL A 1 235 ? 130.203 89.535  147.817 1.00 82.89  ? 235 VAL B N   1 
ATOM   1297 C  CA  . VAL A 1 235 ? 129.971 89.029  146.466 1.00 82.89  ? 235 VAL B CA  1 
ATOM   1298 C  C   . VAL A 1 235 ? 128.710 89.644  145.873 1.00 82.89  ? 235 VAL B C   1 
ATOM   1299 O  O   . VAL A 1 235 ? 128.696 90.066  144.709 1.00 82.89  ? 235 VAL B O   1 
ATOM   1300 C  CB  . VAL A 1 235 ? 129.903 87.491  146.479 1.00 82.89  ? 235 VAL B CB  1 
ATOM   1301 C  CG1 . VAL A 1 235 ? 129.464 86.966  145.125 1.00 82.89  ? 235 VAL B CG1 1 
ATOM   1302 C  CG2 . VAL A 1 235 ? 131.252 86.908  146.865 1.00 82.89  ? 235 VAL B CG2 1 
ATOM   1303 N  N   . THR A 1 236 ? 127.636 89.715  146.662 1.00 79.14  ? 236 THR B N   1 
ATOM   1304 C  CA  . THR A 1 236 ? 126.390 90.289  146.166 1.00 79.14  ? 236 THR B CA  1 
ATOM   1305 C  C   . THR A 1 236 ? 126.556 91.768  145.843 1.00 79.14  ? 236 THR B C   1 
ATOM   1306 O  O   . THR A 1 236 ? 125.996 92.264  144.858 1.00 79.14  ? 236 THR B O   1 
ATOM   1307 C  CB  . THR A 1 236 ? 125.275 90.082  147.190 1.00 79.14  ? 236 THR B CB  1 
ATOM   1308 O  OG1 . THR A 1 236 ? 125.118 88.682  147.448 1.00 79.14  ? 236 THR B OG1 1 
ATOM   1309 C  CG2 . THR A 1 236 ? 123.960 90.637  146.670 1.00 79.14  ? 236 THR B CG2 1 
ATOM   1310 N  N   . ARG A 1 237 ? 127.319 92.492  146.663 1.00 79.75  ? 237 ARG B N   1 
ATOM   1311 C  CA  . ARG A 1 237 ? 127.538 93.908  146.403 1.00 79.75  ? 237 ARG B CA  1 
ATOM   1312 C  C   . ARG A 1 237 ? 128.362 94.114  145.137 1.00 79.75  ? 237 ARG B C   1 
ATOM   1313 O  O   . ARG A 1 237 ? 128.073 95.018  144.341 1.00 79.75  ? 237 ARG B O   1 
ATOM   1314 C  CB  . ARG A 1 237 ? 128.204 94.557  147.613 1.00 79.75  ? 237 ARG B CB  1 
ATOM   1315 C  CG  . ARG A 1 237 ? 128.020 96.057  147.682 1.00 79.75  ? 237 ARG B CG  1 
ATOM   1316 C  CD  . ARG A 1 237 ? 129.004 96.696  148.641 1.00 79.75  ? 237 ARG B CD  1 
ATOM   1317 N  NE  . ARG A 1 237 ? 128.539 96.665  150.023 1.00 79.75  ? 237 ARG B NE  1 
ATOM   1318 C  CZ  . ARG A 1 237 ? 128.812 95.699  150.889 1.00 79.75  ? 237 ARG B CZ  1 
ATOM   1319 N  NH1 . ARG A 1 237 ? 129.564 94.663  150.556 1.00 79.75  ? 237 ARG B NH1 1 
ATOM   1320 N  NH2 . ARG A 1 237 ? 128.323 95.777  152.123 1.00 79.75  ? 237 ARG B NH2 1 
ATOM   1321 N  N   . LYS A 1 238 ? 129.381 93.277  144.920 1.00 74.37  ? 238 LYS B N   1 
ATOM   1322 C  CA  . LYS A 1 238 ? 130.108 93.336  143.655 1.00 74.37  ? 238 LYS B CA  1 
ATOM   1323 C  C   . LYS A 1 238 ? 129.178 93.061  142.482 1.00 74.37  ? 238 LYS B C   1 
ATOM   1324 O  O   . LYS A 1 238 ? 129.233 93.751  141.454 1.00 74.37  ? 238 LYS B O   1 
ATOM   1325 C  CB  . LYS A 1 238 ? 131.262 92.334  143.658 1.00 74.37  ? 238 LYS B CB  1 
ATOM   1326 C  CG  . LYS A 1 238 ? 132.365 92.645  144.646 1.00 74.37  ? 238 LYS B CG  1 
ATOM   1327 C  CD  . LYS A 1 238 ? 133.187 91.404  144.941 1.00 74.37  ? 238 LYS B CD  1 
ATOM   1328 C  CE  . LYS A 1 238 ? 134.432 91.347  144.072 1.00 74.37  ? 238 LYS B CE  1 
ATOM   1329 N  NZ  . LYS A 1 238 ? 135.333 92.509  144.312 1.00 74.37  ? 238 LYS B NZ  1 
ATOM   1330 N  N   . LEU A 1 239 ? 128.307 92.060  142.627 1.00 67.38  ? 239 LEU B N   1 
ATOM   1331 C  CA  . LEU A 1 239 ? 127.381 91.706  141.558 1.00 67.38  ? 239 LEU B CA  1 
ATOM   1332 C  C   . LEU A 1 239 ? 126.460 92.870  141.220 1.00 67.38  ? 239 LEU B C   1 
ATOM   1333 O  O   . LEU A 1 239 ? 126.256 93.193  140.045 1.00 67.38  ? 239 LEU B O   1 
ATOM   1334 C  CB  . LEU A 1 239 ? 126.570 90.477  141.968 1.00 67.38  ? 239 LEU B CB  1 
ATOM   1335 C  CG  . LEU A 1 239 ? 125.401 90.057  141.078 1.00 67.38  ? 239 LEU B CG  1 
ATOM   1336 C  CD1 . LEU A 1 239 ? 125.849 89.898  139.639 1.00 67.38  ? 239 LEU B CD1 1 
ATOM   1337 C  CD2 . LEU A 1 239 ? 124.780 88.772  141.593 1.00 67.38  ? 239 LEU B CD2 1 
ATOM   1338 N  N   . THR A 1 240 ? 125.901 93.523  142.241 1.00 66.07  ? 240 THR B N   1 
ATOM   1339 C  CA  . THR A 1 240 ? 124.958 94.605  141.976 1.00 66.07  ? 240 THR B CA  1 
ATOM   1340 C  C   . THR A 1 240 ? 125.667 95.833  141.411 1.00 66.07  ? 240 THR B C   1 
ATOM   1341 O  O   . THR A 1 240 ? 125.131 96.509  140.521 1.00 66.07  ? 240 THR B O   1 
ATOM   1342 C  CB  . THR A 1 240 ? 124.158 94.948  143.238 1.00 66.07  ? 240 THR B CB  1 
ATOM   1343 O  OG1 . THR A 1 240 ? 123.118 95.875  142.906 1.00 66.07  ? 240 THR B OG1 1 
ATOM   1344 C  CG2 . THR A 1 240 ? 125.033 95.552  144.316 1.00 66.07  ? 240 THR B CG2 1 
ATOM   1345 N  N   . CYS A 1 241 ? 126.885 96.122  141.881 1.00 62.62  ? 241 CYS B N   1 
ATOM   1346 C  CA  . CYS A 1 241 ? 127.645 97.226  141.307 1.00 62.62  ? 241 CYS B CA  1 
ATOM   1347 C  C   . CYS A 1 241 ? 127.910 96.988  139.827 1.00 62.62  ? 241 CYS B C   1 
ATOM   1348 O  O   . CYS A 1 241 ? 127.671 97.867  138.985 1.00 62.62  ? 241 CYS B O   1 
ATOM   1349 C  CB  . CYS A 1 241 ? 128.959 97.406  142.066 1.00 62.62  ? 241 CYS B CB  1 
ATOM   1350 S  SG  . CYS A 1 241 ? 128.780 98.071  143.734 1.00 62.62  ? 241 CYS B SG  1 
ATOM   1351 N  N   . LEU A 1 242 ? 128.383 95.787  139.488 1.00 59.32  ? 242 LEU B N   1 
ATOM   1352 C  CA  . LEU A 1 242 ? 128.681 95.483  138.095 1.00 59.32  ? 242 LEU B CA  1 
ATOM   1353 C  C   . LEU A 1 242 ? 127.423 95.504  137.241 1.00 59.32  ? 242 LEU B C   1 
ATOM   1354 O  O   . LEU A 1 242 ? 127.449 95.985  136.101 1.00 59.32  ? 242 LEU B O   1 
ATOM   1355 C  CB  . LEU A 1 242 ? 129.376 94.128  137.992 1.00 59.32  ? 242 LEU B CB  1 
ATOM   1356 C  CG  . LEU A 1 242 ? 130.897 94.192  138.095 1.00 59.32  ? 242 LEU B CG  1 
ATOM   1357 C  CD1 . LEU A 1 242 ? 131.499 92.827  137.848 1.00 59.32  ? 242 LEU B CD1 1 
ATOM   1358 C  CD2 . LEU A 1 242 ? 131.448 95.210  137.114 1.00 59.32  ? 242 LEU B CD2 1 
ATOM   1359 N  N   . CYS A 1 243 ? 126.311 94.982  137.765 1.00 55.54  ? 243 CYS B N   1 
ATOM   1360 C  CA  . CYS A 1 243 ? 125.097 94.932  136.960 1.00 55.54  ? 243 CYS B CA  1 
ATOM   1361 C  C   . CYS A 1 243 ? 124.566 96.331  136.687 1.00 55.54  ? 243 CYS B C   1 
ATOM   1362 O  O   . CYS A 1 243 ? 124.116 96.616  135.574 1.00 55.54  ? 243 CYS B O   1 
ATOM   1363 C  CB  . CYS A 1 243 ? 124.030 94.072  137.635 1.00 55.54  ? 243 CYS B CB  1 
ATOM   1364 S  SG  . CYS A 1 243 ? 123.148 94.850  138.996 1.00 55.54  ? 243 CYS B SG  1 
ATOM   1365 N  N   . ILE A 1 244 ? 124.623 97.226  137.678 1.00 50.43  ? 244 ILE B N   1 
ATOM   1366 C  CA  . ILE A 1 244 ? 124.209 98.605  137.430 1.00 50.43  ? 244 ILE B CA  1 
ATOM   1367 C  C   . ILE A 1 244 ? 125.123 99.260  136.403 1.00 50.43  ? 244 ILE B C   1 
ATOM   1368 O  O   . ILE A 1 244 ? 124.657 99.924  135.462 1.00 50.43  ? 244 ILE B O   1 
ATOM   1369 C  CB  . ILE A 1 244 ? 124.182 99.401  138.746 1.00 50.43  ? 244 ILE B CB  1 
ATOM   1370 C  CG1 . ILE A 1 244 ? 123.010 98.951  139.609 1.00 50.43  ? 244 ILE B CG1 1 
ATOM   1371 C  CG2 . ILE A 1 244 ? 124.080 100.887 138.467 1.00 50.43  ? 244 ILE B CG2 1 
ATOM   1372 C  CD1 . ILE A 1 244 ? 122.974 99.624  140.939 1.00 50.43  ? 244 ILE B CD1 1 
ATOM   1373 N  N   . ALA A 1 245 ? 126.440 99.071  136.557 1.00 50.48  ? 245 ALA B N   1 
ATOM   1374 C  CA  . ALA A 1 245 ? 127.391 99.692  135.640 1.00 50.48  ? 245 ALA B CA  1 
ATOM   1375 C  C   . ALA A 1 245 ? 127.152 99.239  134.208 1.00 50.48  ? 245 ALA B C   1 
ATOM   1376 O  O   . ALA A 1 245 ? 127.207 100.046 133.273 1.00 50.48  ? 245 ALA B O   1 
ATOM   1377 C  CB  . ALA A 1 245 ? 128.821 99.360  136.062 1.00 50.48  ? 245 ALA B CB  1 
ATOM   1378 N  N   . TYR A 1 246 ? 126.889 97.947  134.014 1.00 49.72  ? 246 TYR B N   1 
ATOM   1379 C  CA  . TYR A 1 246 ? 126.691 97.430  132.666 1.00 49.72  ? 246 TYR B CA  1 
ATOM   1380 C  C   . TYR A 1 246 ? 125.320 97.803  132.118 1.00 49.72  ? 246 TYR B C   1 
ATOM   1381 O  O   . TYR A 1 246 ? 125.186 98.102  130.925 1.00 49.72  ? 246 TYR B O   1 
ATOM   1382 C  CB  . TYR A 1 246 ? 126.875 95.914  132.654 1.00 49.72  ? 246 TYR B CB  1 
ATOM   1383 C  CG  . TYR A 1 246 ? 128.291 95.457  132.944 1.00 49.72  ? 246 TYR B CG  1 
ATOM   1384 C  CD1 . TYR A 1 246 ? 129.323 96.370  133.101 1.00 49.72  ? 246 TYR B CD1 1 
ATOM   1385 C  CD2 . TYR A 1 246 ? 128.587 94.110  133.058 1.00 49.72  ? 246 TYR B CD2 1 
ATOM   1386 C  CE1 . TYR A 1 246 ? 130.611 95.955  133.361 1.00 49.72  ? 246 TYR B CE1 1 
ATOM   1387 C  CE2 . TYR A 1 246 ? 129.876 93.685  133.320 1.00 49.72  ? 246 TYR B CE2 1 
ATOM   1388 C  CZ  . TYR A 1 246 ? 130.883 94.611  133.470 1.00 49.72  ? 246 TYR B CZ  1 
ATOM   1389 O  OH  . TYR A 1 246 ? 132.164 94.191  133.731 1.00 49.72  ? 246 TYR B OH  1 
ATOM   1390 N  N   . SER A 1 247 ? 124.294 97.809  132.972 1.00 48.02  ? 247 SER B N   1 
ATOM   1391 C  CA  . SER A 1 247 ? 122.946 98.100  132.508 1.00 48.02  ? 247 SER B CA  1 
ATOM   1392 C  C   . SER A 1 247 ? 122.795 99.548  132.084 1.00 48.02  ? 247 SER B C   1 
ATOM   1393 O  O   . SER A 1 247 ? 122.015 99.836  131.172 1.00 48.02  ? 247 SER B O   1 
ATOM   1394 C  CB  . SER A 1 247 ? 121.933 97.763  133.595 1.00 48.02  ? 247 SER B CB  1 
ATOM   1395 O  OG  . SER A 1 247 ? 121.926 96.372  133.843 1.00 48.02  ? 247 SER B OG  1 
ATOM   1396 N  N   . SER A 1 248 ? 123.516 100.471 132.725 1.00 47.83  ? 248 SER B N   1 
ATOM   1397 C  CA  . SER A 1 248 ? 123.460 101.860 132.277 1.00 47.83  ? 248 SER B CA  1 
ATOM   1398 C  C   . SER A 1 248 ? 123.823 101.970 130.800 1.00 47.83  ? 248 SER B C   1 
ATOM   1399 O  O   . SER A 1 248 ? 123.054 102.511 129.992 1.00 47.83  ? 248 SER B O   1 
ATOM   1400 C  CB  . SER A 1 248 ? 124.393 102.721 133.125 1.00 47.83  ? 248 SER B CB  1 
ATOM   1401 O  OG  . SER A 1 248 ? 123.916 102.833 134.452 1.00 47.83  ? 248 SER B OG  1 
ATOM   1402 N  N   . THR A 1 249 ? 124.977 101.419 130.421 1.00 47.77  ? 249 THR B N   1 
ATOM   1403 C  CA  . THR A 1 249 ? 125.406 101.477 129.028 1.00 47.77  ? 249 THR B CA  1 
ATOM   1404 C  C   . THR A 1 249 ? 124.496 100.652 128.128 1.00 47.77  ? 249 THR B C   1 
ATOM   1405 O  O   . THR A 1 249 ? 124.182 101.074 127.010 1.00 47.77  ? 249 THR B O   1 
ATOM   1406 C  CB  . THR A 1 249 ? 126.850 101.002 128.901 1.00 47.77  ? 249 THR B CB  1 
ATOM   1407 O  OG1 . THR A 1 249 ? 126.955 99.679  129.429 1.00 47.77  ? 249 THR B OG1 1 
ATOM   1408 C  CG2 . THR A 1 249 ? 127.780 101.916 129.674 1.00 47.77  ? 249 THR B CG2 1 
ATOM   1409 N  N   . ILE A 1 250 ? 124.058 99.478  128.593 1.00 46.42  ? 250 ILE B N   1 
ATOM   1410 C  CA  . ILE A 1 250 ? 123.220 98.618  127.760 1.00 46.42  ? 250 ILE B CA  1 
ATOM   1411 C  C   . ILE A 1 250 ? 121.909 99.313  127.415 1.00 46.42  ? 250 ILE B C   1 
ATOM   1412 O  O   . ILE A 1 250 ? 121.440 99.252  126.273 1.00 46.42  ? 250 ILE B O   1 
ATOM   1413 C  CB  . ILE A 1 250 ? 122.979 97.266  128.455 1.00 46.42  ? 250 ILE B CB  1 
ATOM   1414 C  CG1 . ILE A 1 250 ? 124.219 96.381  128.351 1.00 46.42  ? 250 ILE B CG1 1 
ATOM   1415 C  CG2 . ILE A 1 250 ? 121.782 96.564  127.851 1.00 46.42  ? 250 ILE B CG2 1 
ATOM   1416 C  CD1 . ILE A 1 250 ? 124.206 95.211  129.304 1.00 46.42  ? 250 ILE B CD1 1 
ATOM   1417 N  N   . GLY A 1 251 ? 121.293 99.978  128.393 1.00 46.09  ? 251 GLY B N   1 
ATOM   1418 C  CA  . GLY A 1 251 ? 120.115 100.774 128.114 1.00 46.09  ? 251 GLY B CA  1 
ATOM   1419 C  C   . GLY A 1 251 ? 120.408 102.039 127.342 1.00 46.09  ? 251 GLY B C   1 
ATOM   1420 O  O   . GLY A 1 251 ? 119.499 102.598 126.722 1.00 46.09  ? 251 GLY B O   1 
ATOM   1421 N  N   . GLY A 1 252 ? 121.658 102.507 127.370 1.00 48.33  ? 252 GLY B N   1 
ATOM   1422 C  CA  . GLY A 1 252 ? 122.020 103.650 126.547 1.00 48.33  ? 252 GLY B CA  1 
ATOM   1423 C  C   . GLY A 1 252 ? 121.882 103.377 125.060 1.00 48.33  ? 252 GLY B C   1 
ATOM   1424 O  O   . GLY A 1 252 ? 121.554 104.276 124.283 1.00 48.33  ? 252 GLY B O   1 
ATOM   1425 N  N   . LEU A 1 253 ? 122.131 102.133 124.644 1.00 47.05  ? 253 LEU B N   1 
ATOM   1426 C  CA  . LEU A 1 253 ? 122.077 101.779 123.228 1.00 47.05  ? 253 LEU B CA  1 
ATOM   1427 C  C   . LEU A 1 253 ? 120.683 101.913 122.632 1.00 47.05  ? 253 LEU B C   1 
ATOM   1428 O  O   . LEU A 1 253 ? 120.561 102.142 121.424 1.00 47.05  ? 253 LEU B O   1 
ATOM   1429 C  CB  . LEU A 1 253 ? 122.554 100.341 123.019 1.00 47.05  ? 253 LEU B CB  1 
ATOM   1430 C  CG  . LEU A 1 253 ? 124.035 100.045 122.800 1.00 47.05  ? 253 LEU B CG  1 
ATOM   1431 C  CD1 . LEU A 1 253 ? 124.811 100.216 124.080 1.00 47.05  ? 253 LEU B CD1 1 
ATOM   1432 C  CD2 . LEU A 1 253 ? 124.199 98.635  122.267 1.00 47.05  ? 253 LEU B CD2 1 
ATOM   1433 N  N   . THR A 1 254 ? 119.634 101.765 123.442 1.00 48.45  ? 254 THR B N   1 
ATOM   1434 C  CA  . THR A 1 254 ? 118.298 101.564 122.892 1.00 48.45  ? 254 THR B CA  1 
ATOM   1435 C  C   . THR A 1 254 ? 117.795 102.792 122.140 1.00 48.45  ? 254 THR B C   1 
ATOM   1436 O  O   . THR A 1 254 ? 117.184 102.661 121.074 1.00 48.45  ? 254 THR B O   1 
ATOM   1437 C  CB  . THR A 1 254 ? 117.329 101.181 124.006 1.00 48.45  ? 254 THR B CB  1 
ATOM   1438 O  OG1 . THR A 1 254 ? 117.928 100.171 124.826 1.00 48.45  ? 254 THR B OG1 1 
ATOM   1439 C  CG2 . THR A 1 254 ? 116.048 100.631 123.418 1.00 48.45  ? 254 THR B CG2 1 
ATOM   1440 N  N   . THR A 1 255 ? 118.034 103.988 122.669 1.00 50.77  ? 255 THR B N   1 
ATOM   1441 C  CA  . THR A 1 255 ? 117.532 105.213 122.065 1.00 50.77  ? 255 THR B CA  1 
ATOM   1442 C  C   . THR A 1 255 ? 118.685 106.075 121.569 1.00 50.77  ? 255 THR B C   1 
ATOM   1443 O  O   . THR A 1 255 ? 119.835 105.912 121.982 1.00 50.77  ? 255 THR B O   1 
ATOM   1444 C  CB  . THR A 1 255 ? 116.676 106.016 123.052 1.00 50.77  ? 255 THR B CB  1 
ATOM   1445 O  OG1 . THR A 1 255 ? 117.413 106.232 124.260 1.00 50.77  ? 255 THR B OG1 1 
ATOM   1446 C  CG2 . THR A 1 255 ? 115.395 105.271 123.372 1.00 50.77  ? 255 THR B CG2 1 
ATOM   1447 N  N   . ILE A 1 256 ? 118.355 107.003 120.668 1.00 53.20  ? 256 ILE B N   1 
ATOM   1448 C  CA  . ILE A 1 256 ? 119.369 107.885 120.100 1.00 53.20  ? 256 ILE B CA  1 
ATOM   1449 C  C   . ILE A 1 256 ? 119.967 108.782 121.174 1.00 53.20  ? 256 ILE B C   1 
ATOM   1450 O  O   . ILE A 1 256 ? 121.179 109.018 121.201 1.00 53.20  ? 256 ILE B O   1 
ATOM   1451 C  CB  . ILE A 1 256 ? 118.780 108.712 118.944 1.00 53.20  ? 256 ILE B CB  1 
ATOM   1452 C  CG1 . ILE A 1 256 ? 118.217 107.796 117.861 1.00 53.20  ? 256 ILE B CG1 1 
ATOM   1453 C  CG2 . ILE A 1 256 ? 119.835 109.626 118.356 1.00 53.20  ? 256 ILE B CG2 1 
ATOM   1454 C  CD1 . ILE A 1 256 ? 117.671 108.541 116.667 1.00 53.20  ? 256 ILE B CD1 1 
ATOM   1455 N  N   . THR A 1 257 ? 119.136 109.297 122.073 1.00 54.22  ? 257 THR B N   1 
ATOM   1456 C  CA  . THR A 1 257 ? 119.593 110.228 123.094 1.00 54.22  ? 257 THR B CA  1 
ATOM   1457 C  C   . THR A 1 257 ? 120.188 109.535 124.312 1.00 54.22  ? 257 THR B C   1 
ATOM   1458 O  O   . THR A 1 257 ? 120.585 110.218 125.261 1.00 54.22  ? 257 THR B O   1 
ATOM   1459 C  CB  . THR A 1 257 ? 118.440 111.131 123.535 1.00 54.22  ? 257 THR B CB  1 
ATOM   1460 O  OG1 . THR A 1 257 ? 117.443 110.343 124.195 1.00 54.22  ? 257 THR B OG1 1 
ATOM   1461 C  CG2 . THR A 1 257 ? 117.821 111.819 122.331 1.00 54.22  ? 257 THR B CG2 1 
ATOM   1462 N  N   . GLY A 1 258 ? 120.255 108.203 124.311 1.00 52.12  ? 258 GLY B N   1 
ATOM   1463 C  CA  . GLY A 1 258 ? 120.766 107.499 125.475 1.00 52.12  ? 258 GLY B CA  1 
ATOM   1464 C  C   . GLY A 1 258 ? 122.230 107.786 125.749 1.00 52.12  ? 258 GLY B C   1 
ATOM   1465 O  O   . GLY A 1 258 ? 122.627 107.985 126.899 1.00 52.12  ? 258 GLY B O   1 
ATOM   1466 N  N   . THR A 1 259 ? 123.050 107.815 124.702 1.00 53.65  ? 259 THR B N   1 
ATOM   1467 C  CA  . THR A 1 259 ? 124.491 107.955 124.844 1.00 53.65  ? 259 THR B CA  1 
ATOM   1468 C  C   . THR A 1 259 ? 124.995 109.023 123.884 1.00 53.65  ? 259 THR B C   1 
ATOM   1469 O  O   . THR A 1 259 ? 124.450 109.205 122.792 1.00 53.65  ? 259 THR B O   1 
ATOM   1470 C  CB  . THR A 1 259 ? 125.203 106.614 124.577 1.00 53.65  ? 259 THR B CB  1 
ATOM   1471 O  OG1 . THR A 1 259 ? 124.679 105.613 125.457 1.00 53.65  ? 259 THR B OG1 1 
ATOM   1472 C  CG2 . THR A 1 259 ? 126.702 106.728 124.811 1.00 53.65  ? 259 THR B CG2 1 
ATOM   1473 N  N   . SER A 1 260 ? 126.042 109.738 124.307 1.00 53.80  ? 260 SER B N   1 
ATOM   1474 C  CA  . SER A 1 260 ? 126.644 110.752 123.449 1.00 53.80  ? 260 SER B CA  1 
ATOM   1475 C  C   . SER A 1 260 ? 127.210 110.147 122.171 1.00 53.80  ? 260 SER B C   1 
ATOM   1476 O  O   . SER A 1 260 ? 127.294 110.832 121.146 1.00 53.80  ? 260 SER B O   1 
ATOM   1477 C  CB  . SER A 1 260 ? 127.739 111.500 124.208 1.00 53.80  ? 260 SER B CB  1 
ATOM   1478 O  OG  . SER A 1 260 ? 128.731 110.606 124.681 1.00 53.80  ? 260 SER B OG  1 
ATOM   1479 N  N   . THR A 1 261 ? 127.611 108.874 122.212 1.00 49.98  ? 261 THR B N   1 
ATOM   1480 C  CA  . THR A 1 261 ? 128.082 108.207 121.002 1.00 49.98  ? 261 THR B CA  1 
ATOM   1481 C  C   . THR A 1 261 ? 126.983 108.144 119.950 1.00 49.98  ? 261 THR B C   1 
ATOM   1482 O  O   . THR A 1 261 ? 127.231 108.382 118.760 1.00 49.98  ? 261 THR B O   1 
ATOM   1483 C  CB  . THR A 1 261 ? 128.581 106.803 121.340 1.00 49.98  ? 261 THR B CB  1 
ATOM   1484 O  OG1 . THR A 1 261 ? 129.621 106.887 122.321 1.00 49.98  ? 261 THR B OG1 1 
ATOM   1485 C  CG2 . THR A 1 261 ? 129.115 106.113 120.103 1.00 49.98  ? 261 THR B CG2 1 
ATOM   1486 N  N   . ASN A 1 262 ? 125.759 107.826 120.371 1.00 51.56  ? 262 ASN B N   1 
ATOM   1487 C  CA  . ASN A 1 262 ? 124.640 107.810 119.439 1.00 51.56  ? 262 ASN B CA  1 
ATOM   1488 C  C   . ASN A 1 262 ? 124.349 109.208 118.907 1.00 51.56  ? 262 ASN B C   1 
ATOM   1489 O  O   . ASN A 1 262 ? 123.991 109.366 117.736 1.00 51.56  ? 262 ASN B O   1 
ATOM   1490 C  CB  . ASN A 1 262 ? 123.407 107.214 120.111 1.00 51.56  ? 262 ASN B CB  1 
ATOM   1491 C  CG  . ASN A 1 262 ? 123.623 105.784 120.556 1.00 51.56  ? 262 ASN B CG  1 
ATOM   1492 O  OD1 . ASN A 1 262 ? 124.489 105.084 120.035 1.00 51.56  ? 262 ASN B OD1 1 
ATOM   1493 N  ND2 . ASN A 1 262 ? 122.835 105.341 121.525 1.00 51.56  ? 262 ASN B ND2 1 
ATOM   1494 N  N   . LEU A 1 263 ? 124.503 110.234 119.749 1.00 55.11  ? 263 LEU B N   1 
ATOM   1495 C  CA  . LEU A 1 263 ? 124.353 111.607 119.274 1.00 55.11  ? 263 LEU B CA  1 
ATOM   1496 C  C   . LEU A 1 263 ? 125.374 111.932 118.192 1.00 55.11  ? 263 LEU B C   1 
ATOM   1497 O  O   . LEU A 1 263 ? 125.033 112.527 117.163 1.00 55.11  ? 263 LEU B O   1 
ATOM   1498 C  CB  . LEU A 1 263 ? 124.492 112.591 120.435 1.00 55.11  ? 263 LEU B CB  1 
ATOM   1499 C  CG  . LEU A 1 263 ? 123.228 113.110 121.120 1.00 55.11  ? 263 LEU B CG  1 
ATOM   1500 C  CD1 . LEU A 1 263 ? 122.310 111.975 121.500 1.00 55.11  ? 263 LEU B CD1 1 
ATOM   1501 C  CD2 . LEU A 1 263 ? 123.596 113.926 122.343 1.00 55.11  ? 263 LEU B CD2 1 
ATOM   1502 N  N   . ILE A 1 264 ? 126.634 111.552 118.411 1.00 52.11  ? 264 ILE B N   1 
ATOM   1503 C  CA  . ILE A 1 264 ? 127.676 111.830 117.428 1.00 52.11  ? 264 ILE B CA  1 
ATOM   1504 C  C   . ILE A 1 264 ? 127.380 111.107 116.123 1.00 52.11  ? 264 ILE B C   1 
ATOM   1505 O  O   . ILE A 1 264 ? 127.487 111.689 115.036 1.00 52.11  ? 264 ILE B O   1 
ATOM   1506 C  CB  . ILE A 1 264 ? 129.057 111.443 117.985 1.00 52.11  ? 264 ILE B CB  1 
ATOM   1507 C  CG1 . ILE A 1 264 ? 129.410 112.322 119.181 1.00 52.11  ? 264 ILE B CG1 1 
ATOM   1508 C  CG2 . ILE A 1 264 ? 130.117 111.564 116.908 1.00 52.11  ? 264 ILE B CG2 1 
ATOM   1509 C  CD1 . ILE A 1 264 ? 130.711 111.961 119.835 1.00 52.11  ? 264 ILE B CD1 1 
ATOM   1510 N  N   . PHE A 1 265 ? 127.000 109.830 116.207 1.00 54.24  ? 265 PHE B N   1 
ATOM   1511 C  CA  . PHE A 1 265 ? 126.697 109.084 114.990 1.00 54.24  ? 265 PHE B CA  1 
ATOM   1512 C  C   . PHE A 1 265 ? 125.514 109.693 114.252 1.00 54.24  ? 265 PHE B C   1 
ATOM   1513 O  O   . PHE A 1 265 ? 125.545 109.828 113.024 1.00 54.24  ? 265 PHE B O   1 
ATOM   1514 C  CB  . PHE A 1 265 ? 126.416 107.620 115.310 1.00 54.24  ? 265 PHE B CB  1 
ATOM   1515 C  CG  . PHE A 1 265 ? 125.792 106.869 114.170 1.00 54.24  ? 265 PHE B CG  1 
ATOM   1516 C  CD1 . PHE A 1 265 ? 126.470 106.714 112.976 1.00 54.24  ? 265 PHE B CD1 1 
ATOM   1517 C  CD2 . PHE A 1 265 ? 124.522 106.335 114.283 1.00 54.24  ? 265 PHE B CD2 1 
ATOM   1518 C  CE1 . PHE A 1 265 ? 125.900 106.030 111.922 1.00 54.24  ? 265 PHE B CE1 1 
ATOM   1519 C  CE2 . PHE A 1 265 ? 123.948 105.650 113.230 1.00 54.24  ? 265 PHE B CE2 1 
ATOM   1520 C  CZ  . PHE A 1 265 ? 124.638 105.498 112.050 1.00 54.24  ? 265 PHE B CZ  1 
ATOM   1521 N  N   . ALA A 1 266 ? 124.462 110.069 114.982 1.00 59.46  ? 266 ALA B N   1 
ATOM   1522 C  CA  . ALA A 1 266 ? 123.284 110.643 114.345 1.00 59.46  ? 266 ALA B CA  1 
ATOM   1523 C  C   . ALA A 1 266 ? 123.618 111.958 113.656 1.00 59.46  ? 266 ALA B C   1 
ATOM   1524 O  O   . ALA A 1 266 ? 123.213 112.192 112.512 1.00 59.46  ? 266 ALA B O   1 
ATOM   1525 C  CB  . ALA A 1 266 ? 122.175 110.840 115.378 1.00 59.46  ? 266 ALA B CB  1 
ATOM   1526 N  N   . GLU A 1 267 ? 124.368 112.829 114.336 1.00 62.39  ? 267 GLU B N   1 
ATOM   1527 C  CA  . GLU A 1 267 ? 124.725 114.114 113.745 1.00 62.39  ? 267 GLU B CA  1 
ATOM   1528 C  C   . GLU A 1 267 ? 125.596 113.927 112.510 1.00 62.39  ? 267 GLU B C   1 
ATOM   1529 O  O   . GLU A 1 267 ? 125.366 114.561 111.472 1.00 62.39  ? 267 GLU B O   1 
ATOM   1530 C  CB  . GLU A 1 267 ? 125.435 114.986 114.778 1.00 62.39  ? 267 GLU B CB  1 
ATOM   1531 C  CG  . GLU A 1 267 ? 124.531 116.000 115.448 1.00 62.39  ? 267 GLU B CG  1 
ATOM   1532 C  CD  . GLU A 1 267 ? 125.070 116.461 116.785 1.00 62.39  ? 267 GLU B CD  1 
ATOM   1533 O  OE1 . GLU A 1 267 ? 126.295 116.350 117.001 1.00 62.39  ? 267 GLU B OE1 1 
ATOM   1534 O  OE2 . GLU A 1 267 ? 124.269 116.933 117.619 1.00 62.39  ? 267 GLU B OE2 1 
ATOM   1535 N  N   . TYR A 1 268 ? 126.602 113.052 112.600 1.00 59.70  ? 268 TYR B N   1 
ATOM   1536 C  CA  . TYR A 1 268 ? 127.481 112.825 111.460 1.00 59.70  ? 268 TYR B CA  1 
ATOM   1537 C  C   . TYR A 1 268 ? 126.716 112.243 110.281 1.00 59.70  ? 268 TYR B C   1 
ATOM   1538 O  O   . TYR A 1 268 ? 126.936 112.642 109.133 1.00 59.70  ? 268 TYR B O   1 
ATOM   1539 C  CB  . TYR A 1 268 ? 128.632 111.904 111.859 1.00 59.70  ? 268 TYR B CB  1 
ATOM   1540 C  CG  . TYR A 1 268 ? 129.603 111.604 110.738 1.00 59.70  ? 268 TYR B CG  1 
ATOM   1541 C  CD1 . TYR A 1 268 ? 129.396 110.531 109.882 1.00 59.70  ? 268 TYR B CD1 1 
ATOM   1542 C  CD2 . TYR A 1 268 ? 130.733 112.384 110.547 1.00 59.70  ? 268 TYR B CD2 1 
ATOM   1543 C  CE1 . TYR A 1 268 ? 130.277 110.254 108.861 1.00 59.70  ? 268 TYR B CE1 1 
ATOM   1544 C  CE2 . TYR A 1 268 ? 131.624 112.112 109.528 1.00 59.70  ? 268 TYR B CE2 1 
ATOM   1545 C  CZ  . TYR A 1 268 ? 131.390 111.045 108.688 1.00 59.70  ? 268 TYR B CZ  1 
ATOM   1546 O  OH  . TYR A 1 268 ? 132.272 110.766 107.670 1.00 59.70  ? 268 TYR B OH  1 
ATOM   1547 N  N   . PHE A 1 269 ? 125.816 111.293 110.540 1.00 64.02  ? 269 PHE B N   1 
ATOM   1548 C  CA  . PHE A 1 269 ? 125.064 110.686 109.450 1.00 64.02  ? 269 PHE B CA  1 
ATOM   1549 C  C   . PHE A 1 269 ? 124.089 111.676 108.830 1.00 64.02  ? 269 PHE B C   1 
ATOM   1550 O  O   . PHE A 1 269 ? 123.871 111.658 107.613 1.00 64.02  ? 269 PHE B O   1 
ATOM   1551 C  CB  . PHE A 1 269 ? 124.330 109.445 109.944 1.00 64.02  ? 269 PHE B CB  1 
ATOM   1552 C  CG  . PHE A 1 269 ? 123.611 108.707 108.862 1.00 64.02  ? 269 PHE B CG  1 
ATOM   1553 C  CD1 . PHE A 1 269 ? 124.314 107.979 107.923 1.00 64.02  ? 269 PHE B CD1 1 
ATOM   1554 C  CD2 . PHE A 1 269 ? 122.231 108.741 108.781 1.00 64.02  ? 269 PHE B CD2 1 
ATOM   1555 C  CE1 . PHE A 1 269 ? 123.656 107.305 106.920 1.00 64.02  ? 269 PHE B CE1 1 
ATOM   1556 C  CE2 . PHE A 1 269 ? 121.567 108.062 107.782 1.00 64.02  ? 269 PHE B CE2 1 
ATOM   1557 C  CZ  . PHE A 1 269 ? 122.281 107.341 106.852 1.00 64.02  ? 269 PHE B CZ  1 
ATOM   1558 N  N   . ASN A 1 270 ? 123.484 112.540 109.646 1.00 65.17  ? 270 ASN B N   1 
ATOM   1559 C  CA  . ASN A 1 270 ? 122.574 113.543 109.106 1.00 65.17  ? 270 ASN B CA  1 
ATOM   1560 C  C   . ASN A 1 270 ? 123.318 114.564 108.256 1.00 65.17  ? 270 ASN B C   1 
ATOM   1561 O  O   . ASN A 1 270 ? 122.816 114.991 107.210 1.00 65.17  ? 270 ASN B O   1 
ATOM   1562 C  CB  . ASN A 1 270 ? 121.819 114.230 110.242 1.00 65.17  ? 270 ASN B CB  1 
ATOM   1563 C  CG  . ASN A 1 270 ? 120.592 113.454 110.675 1.00 65.17  ? 270 ASN B CG  1 
ATOM   1564 O  OD1 . ASN A 1 270 ? 120.459 112.266 110.382 1.00 65.17  ? 270 ASN B OD1 1 
ATOM   1565 N  ND2 . ASN A 1 270 ? 119.687 114.123 111.378 1.00 65.17  ? 270 ASN B ND2 1 
ATOM   1566 N  N   . THR A 1 271 ? 124.514 114.973 108.687 1.00 67.01  ? 271 THR B N   1 
ATOM   1567 C  CA  . THR A 1 271 ? 125.275 115.943 107.904 1.00 67.01  ? 271 THR B CA  1 
ATOM   1568 C  C   . THR A 1 271 ? 125.820 115.326 106.621 1.00 67.01  ? 271 THR B C   1 
ATOM   1569 O  O   . THR A 1 271 ? 125.711 115.924 105.545 1.00 67.01  ? 271 THR B O   1 
ATOM   1570 C  CB  . THR A 1 271 ? 126.417 116.522 108.736 1.00 67.01  ? 271 THR B CB  1 
ATOM   1571 O  OG1 . THR A 1 271 ? 127.253 115.458 109.206 1.00 67.01  ? 271 THR B OG1 1 
ATOM   1572 C  CG2 . THR A 1 271 ? 125.875 117.307 109.920 1.00 67.01  ? 271 THR B CG2 1 
ATOM   1573 N  N   . ARG A 1 272 ? 126.410 114.131 106.711 1.00 65.53  ? 272 ARG B N   1 
ATOM   1574 C  CA  . ARG A 1 272 ? 127.090 113.556 105.556 1.00 65.53  ? 272 ARG B CA  1 
ATOM   1575 C  C   . ARG A 1 272 ? 126.110 113.039 104.510 1.00 65.53  ? 272 ARG B C   1 
ATOM   1576 O  O   . ARG A 1 272 ? 126.413 113.072 103.313 1.00 65.53  ? 272 ARG B O   1 
ATOM   1577 C  CB  . ARG A 1 272 ? 128.030 112.438 106.002 1.00 65.53  ? 272 ARG B CB  1 
ATOM   1578 C  CG  . ARG A 1 272 ? 129.176 112.180 105.038 1.00 65.53  ? 272 ARG B CG  1 
ATOM   1579 C  CD  . ARG A 1 272 ? 129.598 110.720 105.054 1.00 65.53  ? 272 ARG B CD  1 
ATOM   1580 N  NE  . ARG A 1 272 ? 130.541 110.404 103.988 1.00 65.53  ? 272 ARG B NE  1 
ATOM   1581 C  CZ  . ARG A 1 272 ? 131.803 110.809 103.954 1.00 65.53  ? 272 ARG B CZ  1 
ATOM   1582 N  NH1 . ARG A 1 272 ? 132.323 111.536 104.929 1.00 65.53  ? 272 ARG B NH1 1 
ATOM   1583 N  NH2 . ARG A 1 272 ? 132.565 110.471 102.918 1.00 65.53  ? 272 ARG B NH2 1 
ATOM   1584 N  N   . TYR A 1 273 ? 124.943 112.559 104.931 1.00 67.14  ? 273 TYR B N   1 
ATOM   1585 C  CA  . TYR A 1 273 ? 123.912 112.064 104.019 1.00 67.14  ? 273 TYR B CA  1 
ATOM   1586 C  C   . TYR A 1 273 ? 122.594 112.762 104.324 1.00 67.14  ? 273 TYR B C   1 
ATOM   1587 O  O   . TYR A 1 273 ? 121.690 112.177 104.933 1.00 67.14  ? 273 TYR B O   1 
ATOM   1588 C  CB  . TYR A 1 273 ? 123.761 110.546 104.124 1.00 67.14  ? 273 TYR B CB  1 
ATOM   1589 C  CG  . TYR A 1 273 ? 125.050 109.776 103.966 1.00 67.14  ? 273 TYR B CG  1 
ATOM   1590 C  CD1 . TYR A 1 273 ? 125.593 109.546 102.711 1.00 67.14  ? 273 TYR B CD1 1 
ATOM   1591 C  CD2 . TYR A 1 273 ? 125.717 109.268 105.070 1.00 67.14  ? 273 TYR B CD2 1 
ATOM   1592 C  CE1 . TYR A 1 273 ? 126.769 108.838 102.561 1.00 67.14  ? 273 TYR B CE1 1 
ATOM   1593 C  CE2 . TYR A 1 273 ? 126.890 108.557 104.931 1.00 67.14  ? 273 TYR B CE2 1 
ATOM   1594 C  CZ  . TYR A 1 273 ? 127.412 108.346 103.675 1.00 67.14  ? 273 TYR B CZ  1 
ATOM   1595 O  OH  . TYR A 1 273 ? 128.584 107.640 103.531 1.00 67.14  ? 273 TYR B OH  1 
ATOM   1596 N  N   . PRO A 1 274 ? 122.454 114.026 103.918 1.00 73.48  ? 274 PRO B N   1 
ATOM   1597 C  CA  . PRO A 1 274 ? 121.182 114.730 104.151 1.00 73.48  ? 274 PRO B CA  1 
ATOM   1598 C  C   . PRO A 1 274 ? 119.997 114.073 103.467 1.00 73.48  ? 274 PRO B C   1 
ATOM   1599 O  O   . PRO A 1 274 ? 118.874 114.158 103.978 1.00 73.48  ? 274 PRO B O   1 
ATOM   1600 C  CB  . PRO A 1 274 ? 121.449 116.137 103.594 1.00 73.48  ? 274 PRO B CB  1 
ATOM   1601 C  CG  . PRO A 1 274 ? 122.941 116.247 103.492 1.00 73.48  ? 274 PRO B CG  1 
ATOM   1602 C  CD  . PRO A 1 274 ? 123.430 114.868 103.209 1.00 73.48  ? 274 PRO B CD  1 
ATOM   1603 N  N   . ASP A 1 275 ? 120.214 113.426 102.319 1.00 79.43  ? 275 ASP B N   1 
ATOM   1604 C  CA  . ASP A 1 275 ? 119.121 112.749 101.629 1.00 79.43  ? 275 ASP B CA  1 
ATOM   1605 C  C   . ASP A 1 275 ? 118.582 111.593 102.464 1.00 79.43  ? 275 ASP B C   1 
ATOM   1606 O  O   . ASP A 1 275 ? 117.368 111.360 102.507 1.00 79.43  ? 275 ASP B O   1 
ATOM   1607 C  CB  . ASP A 1 275 ? 119.601 112.264 100.258 1.00 79.43  ? 275 ASP B CB  1 
ATOM   1608 C  CG  . ASP A 1 275 ? 118.463 111.833 99.342  1.00 79.43  ? 275 ASP B CG  1 
ATOM   1609 O  OD1 . ASP A 1 275 ? 117.520 111.157 99.803  1.00 79.43  ? 275 ASP B OD1 1 
ATOM   1610 O  OD2 . ASP A 1 275 ? 118.515 112.179 98.143  1.00 79.43  ? 275 ASP B OD2 1 
ATOM   1611 N  N   . CYS A 1 276 ? 119.467 110.865 103.141 1.00 77.88  ? 276 CYS B N   1 
ATOM   1612 C  CA  . CYS A 1 276 ? 119.049 109.732 103.958 1.00 77.88  ? 276 CYS B CA  1 
ATOM   1613 C  C   . CYS A 1 276 ? 118.251 110.220 105.161 1.00 77.88  ? 276 CYS B C   1 
ATOM   1614 O  O   . CYS A 1 276 ? 118.750 111.012 105.967 1.00 77.88  ? 276 CYS B O   1 
ATOM   1615 C  CB  . CYS A 1 276 ? 120.267 108.935 104.415 1.00 77.88  ? 276 CYS B CB  1 
ATOM   1616 N  N   . ARG A 1 277 ? 117.011 109.743 105.282 1.00 80.08  ? 277 ARG B N   1 
ATOM   1617 C  CA  . ARG A 1 277 ? 116.142 110.116 106.391 1.00 80.08  ? 277 ARG B CA  1 
ATOM   1618 C  C   . ARG A 1 277 ? 115.595 108.903 107.132 1.00 80.08  ? 277 ARG B C   1 
ATOM   1619 O  O   . ARG A 1 277 ? 114.719 109.061 107.990 1.00 80.08  ? 277 ARG B O   1 
ATOM   1620 C  CB  . ARG A 1 277 ? 114.981 110.986 105.896 1.00 80.08  ? 277 ARG B CB  1 
ATOM   1621 C  CG  . ARG A 1 277 ? 115.399 112.098 104.950 1.00 80.08  ? 277 ARG B CG  1 
ATOM   1622 C  CD  . ARG A 1 277 ? 114.205 112.940 104.516 1.00 80.08  ? 277 ARG B CD  1 
ATOM   1623 N  NE  . ARG A 1 277 ? 114.587 114.250 103.995 1.00 80.08  ? 277 ARG B NE  1 
ATOM   1624 C  CZ  . ARG A 1 277 ? 115.240 115.183 104.676 1.00 80.08  ? 277 ARG B CZ  1 
ATOM   1625 N  NH1 . ARG A 1 277 ? 115.569 115.016 105.947 1.00 80.08  ? 277 ARG B NH1 1 
ATOM   1626 N  NH2 . ARG A 1 277 ? 115.559 116.323 104.069 1.00 80.08  ? 277 ARG B NH2 1 
ATOM   1627 N  N   . CYS A 1 278 ? 116.085 107.699 106.826 1.00 75.83  ? 278 CYS B N   1 
ATOM   1628 C  CA  . CYS A 1 278 ? 115.590 106.496 107.484 1.00 75.83  ? 278 CYS B CA  1 
ATOM   1629 C  C   . CYS A 1 278 ? 116.003 106.420 108.947 1.00 75.83  ? 278 CYS B C   1 
ATOM   1630 O  O   . CYS A 1 278 ? 115.435 105.618 109.696 1.00 75.83  ? 278 CYS B O   1 
ATOM   1631 C  CB  . CYS A 1 278 ? 116.081 105.252 106.743 1.00 75.83  ? 278 CYS B CB  1 
ATOM   1632 S  SG  . CYS A 1 278 ? 117.878 105.082 106.692 1.00 75.83  ? 278 CYS B SG  1 
ATOM   1633 N  N   . LEU A 1 279 ? 116.972 107.227 109.369 1.00 66.53  ? 279 LEU B N   1 
ATOM   1634 C  CA  . LEU A 1 279 ? 117.450 107.219 110.747 1.00 66.53  ? 279 LEU B CA  1 
ATOM   1635 C  C   . LEU A 1 279 ? 116.666 108.251 111.550 1.00 66.53  ? 279 LEU B C   1 
ATOM   1636 O  O   . LEU A 1 279 ? 116.788 109.457 111.312 1.00 66.53  ? 279 LEU B O   1 
ATOM   1637 C  CB  . LEU A 1 279 ? 118.947 107.508 110.798 1.00 66.53  ? 279 LEU B CB  1 
ATOM   1638 C  CG  . LEU A 1 279 ? 119.665 107.036 112.061 1.00 66.53  ? 279 LEU B CG  1 
ATOM   1639 C  CD1 . LEU A 1 279 ? 119.786 105.523 112.063 1.00 66.53  ? 279 LEU B CD1 1 
ATOM   1640 C  CD2 . LEU A 1 279 ? 121.030 107.692 112.179 1.00 66.53  ? 279 LEU B CD2 1 
ATOM   1641 N  N   . ASN A 1 280 ? 115.866 107.779 112.499 1.00 65.00  ? 280 ASN B N   1 
ATOM   1642 C  CA  . ASN A 1 280 ? 115.120 108.649 113.399 1.00 65.00  ? 280 ASN B CA  1 
ATOM   1643 C  C   . ASN A 1 280 ? 114.853 107.873 114.684 1.00 65.00  ? 280 ASN B C   1 
ATOM   1644 O  O   . ASN A 1 280 ? 115.334 106.748 114.859 1.00 65.00  ? 280 ASN B O   1 
ATOM   1645 C  CB  . ASN A 1 280 ? 113.832 109.154 112.740 1.00 65.00  ? 280 ASN B CB  1 
ATOM   1646 C  CG  . ASN A 1 280 ? 113.092 108.065 111.997 1.00 65.00  ? 280 ASN B CG  1 
ATOM   1647 O  OD1 . ASN A 1 280 ? 113.488 106.902 112.024 1.00 65.00  ? 280 ASN B OD1 1 
ATOM   1648 N  ND2 . ASN A 1 280 ? 112.008 108.437 111.326 1.00 65.00  ? 280 ASN B ND2 1 
ATOM   1649 N  N   . PHE A 1 281 ? 114.083 108.479 115.590 1.00 61.86  ? 281 PHE B N   1 
ATOM   1650 C  CA  . PHE A 1 281 ? 113.877 107.892 116.911 1.00 61.86  ? 281 PHE B CA  1 
ATOM   1651 C  C   . PHE A 1 281 ? 113.165 106.547 116.820 1.00 61.86  ? 281 PHE B C   1 
ATOM   1652 O  O   . PHE A 1 281 ? 113.604 105.556 117.419 1.00 61.86  ? 281 PHE B O   1 
ATOM   1653 C  CB  . PHE A 1 281 ? 113.084 108.864 117.784 1.00 61.86  ? 281 PHE B CB  1 
ATOM   1654 C  CG  . PHE A 1 281 ? 113.267 108.648 119.255 1.00 61.86  ? 281 PHE B CG  1 
ATOM   1655 C  CD1 . PHE A 1 281 ? 114.352 109.196 119.917 1.00 61.86  ? 281 PHE B CD1 1 
ATOM   1656 C  CD2 . PHE A 1 281 ? 112.351 107.906 119.979 1.00 61.86  ? 281 PHE B CD2 1 
ATOM   1657 C  CE1 . PHE A 1 281 ? 114.523 109.002 121.272 1.00 61.86  ? 281 PHE B CE1 1 
ATOM   1658 C  CE2 . PHE A 1 281 ? 112.515 107.708 121.334 1.00 61.86  ? 281 PHE B CE2 1 
ATOM   1659 C  CZ  . PHE A 1 281 ? 113.603 108.257 121.982 1.00 61.86  ? 281 PHE B CZ  1 
ATOM   1660 N  N   . GLY A 1 282 ? 112.065 106.494 116.068 1.00 61.22  ? 282 GLY B N   1 
ATOM   1661 C  CA  . GLY A 1 282 ? 111.280 105.272 116.009 1.00 61.22  ? 282 GLY B CA  1 
ATOM   1662 C  C   . GLY A 1 282 ? 112.038 104.116 115.386 1.00 61.22  ? 282 GLY B C   1 
ATOM   1663 O  O   . GLY A 1 282 ? 112.049 103.005 115.920 1.00 61.22  ? 282 GLY B O   1 
ATOM   1664 N  N   . SER A 1 283 ? 112.691 104.366 114.249 1.00 58.38  ? 283 SER B N   1 
ATOM   1665 C  CA  . SER A 1 283 ? 113.444 103.306 113.587 1.00 58.38  ? 283 SER B CA  1 
ATOM   1666 C  C   . SER A 1 283 ? 114.610 102.841 114.448 1.00 58.38  ? 283 SER B C   1 
ATOM   1667 O  O   . SER A 1 283 ? 114.893 101.637 114.529 1.00 58.38  ? 283 SER B O   1 
ATOM   1668 C  CB  . SER A 1 283 ? 113.940 103.783 112.225 1.00 58.38  ? 283 SER B CB  1 
ATOM   1669 O  OG  . SER A 1 283 ? 114.985 104.727 112.371 1.00 58.38  ? 283 SER B OG  1 
ATOM   1670 N  N   . TRP A 1 284 ? 115.299 103.782 115.097 1.00 55.61  ? 284 TRP B N   1 
ATOM   1671 C  CA  . TRP A 1 284 ? 116.412 103.414 115.963 1.00 55.61  ? 284 TRP B CA  1 
ATOM   1672 C  C   . TRP A 1 284 ? 115.944 102.521 117.102 1.00 55.61  ? 284 TRP B C   1 
ATOM   1673 O  O   . TRP A 1 284 ? 116.550 101.477 117.376 1.00 55.61  ? 284 TRP B O   1 
ATOM   1674 C  CB  . TRP A 1 284 ? 117.099 104.664 116.508 1.00 55.61  ? 284 TRP B CB  1 
ATOM   1675 C  CG  . TRP A 1 284 ? 118.326 104.353 117.303 1.00 55.61  ? 284 TRP B CG  1 
ATOM   1676 C  CD1 . TRP A 1 284 ? 118.381 103.997 118.617 1.00 55.61  ? 284 TRP B CD1 1 
ATOM   1677 C  CD2 . TRP A 1 284 ? 119.679 104.362 116.834 1.00 55.61  ? 284 TRP B CD2 1 
ATOM   1678 N  NE1 . TRP A 1 284 ? 119.683 103.785 118.997 1.00 55.61  ? 284 TRP B NE1 1 
ATOM   1679 C  CE2 . TRP A 1 284 ? 120.500 104.003 117.920 1.00 55.61  ? 284 TRP B CE2 1 
ATOM   1680 C  CE3 . TRP A 1 284 ? 120.275 104.640 115.602 1.00 55.61  ? 284 TRP B CE3 1 
ATOM   1681 C  CZ2 . TRP A 1 284 ? 121.884 103.916 117.812 1.00 55.61  ? 284 TRP B CZ2 1 
ATOM   1682 C  CZ3 . TRP A 1 284 ? 121.649 104.552 115.497 1.00 55.61  ? 284 TRP B CZ3 1 
ATOM   1683 C  CH2 . TRP A 1 284 ? 122.439 104.193 116.594 1.00 55.61  ? 284 TRP B CH2 1 
ATOM   1684 N  N   . PHE A 1 285 ? 114.854 102.907 117.770 1.00 57.10  ? 285 PHE B N   1 
ATOM   1685 C  CA  . PHE A 1 285 ? 114.337 102.070 118.845 1.00 57.10  ? 285 PHE B CA  1 
ATOM   1686 C  C   . PHE A 1 285 ? 113.919 100.704 118.322 1.00 57.10  ? 285 PHE B C   1 
ATOM   1687 O  O   . PHE A 1 285 ? 114.215 99.680  118.946 1.00 57.10  ? 285 PHE B O   1 
ATOM   1688 C  CB  . PHE A 1 285 ? 113.165 102.754 119.546 1.00 57.10  ? 285 PHE B CB  1 
ATOM   1689 C  CG  . PHE A 1 285 ? 112.605 101.961 120.695 1.00 57.10  ? 285 PHE B CG  1 
ATOM   1690 C  CD1 . PHE A 1 285 ? 113.128 102.099 121.967 1.00 57.10  ? 285 PHE B CD1 1 
ATOM   1691 C  CD2 . PHE A 1 285 ? 111.560 101.074 120.500 1.00 57.10  ? 285 PHE B CD2 1 
ATOM   1692 C  CE1 . PHE A 1 285 ? 112.619 101.370 123.022 1.00 57.10  ? 285 PHE B CE1 1 
ATOM   1693 C  CE2 . PHE A 1 285 ? 111.050 100.342 121.552 1.00 57.10  ? 285 PHE B CE2 1 
ATOM   1694 C  CZ  . PHE A 1 285 ? 111.580 100.491 122.814 1.00 57.10  ? 285 PHE B CZ  1 
ATOM   1695 N  N   . THR A 1 286 ? 113.243 100.664 117.171 1.00 59.14  ? 286 THR B N   1 
ATOM   1696 C  CA  . THR A 1 286 ? 112.753 99.388  116.660 1.00 59.14  ? 286 THR B CA  1 
ATOM   1697 C  C   . THR A 1 286 ? 113.898 98.437  116.344 1.00 59.14  ? 286 THR B C   1 
ATOM   1698 O  O   . THR A 1 286 ? 113.816 97.241  116.649 1.00 59.14  ? 286 THR B O   1 
ATOM   1699 C  CB  . THR A 1 286 ? 111.884 99.599  115.420 1.00 59.14  ? 286 THR B CB  1 
ATOM   1700 O  OG1 . THR A 1 286 ? 112.563 100.451 114.493 1.00 59.14  ? 286 THR B OG1 1 
ATOM   1701 C  CG2 . THR A 1 286 ? 110.549 100.218 115.800 1.00 59.14  ? 286 THR B CG2 1 
ATOM   1702 N  N   . PHE A 1 287 ? 114.975 98.934  115.735 1.00 56.73  ? 287 PHE B N   1 
ATOM   1703 C  CA  . PHE A 1 287 ? 116.046 98.011  115.380 1.00 56.73  ? 287 PHE B CA  1 
ATOM   1704 C  C   . PHE A 1 287 ? 117.032 97.776  116.516 1.00 56.73  ? 287 PHE B C   1 
ATOM   1705 O  O   . PHE A 1 287 ? 117.828 96.837  116.431 1.00 56.73  ? 287 PHE B O   1 
ATOM   1706 C  CB  . PHE A 1 287 ? 116.807 98.487  114.130 1.00 56.73  ? 287 PHE B CB  1 
ATOM   1707 C  CG  . PHE A 1 287 ? 117.999 99.362  114.417 1.00 56.73  ? 287 PHE B CG  1 
ATOM   1708 C  CD1 . PHE A 1 287 ? 117.874 100.733 114.482 1.00 56.73  ? 287 PHE B CD1 1 
ATOM   1709 C  CD2 . PHE A 1 287 ? 119.261 98.806  114.570 1.00 56.73  ? 287 PHE B CD2 1 
ATOM   1710 C  CE1 . PHE A 1 287 ? 118.975 101.531 114.729 1.00 56.73  ? 287 PHE B CE1 1 
ATOM   1711 C  CE2 . PHE A 1 287 ? 120.358 99.598  114.821 1.00 56.73  ? 287 PHE B CE2 1 
ATOM   1712 C  CZ  . PHE A 1 287 ? 120.216 100.962 114.898 1.00 56.73  ? 287 PHE B CZ  1 
ATOM   1713 N  N   . SER A 1 288 ? 116.997 98.582  117.580 1.00 52.33  ? 288 SER B N   1 
ATOM   1714 C  CA  . SER A 1 288 ? 117.945 98.400  118.670 1.00 52.33  ? 288 SER B CA  1 
ATOM   1715 C  C   . SER A 1 288 ? 117.356 97.715  119.894 1.00 52.33  ? 288 SER B C   1 
ATOM   1716 O  O   . SER A 1 288 ? 118.120 97.181  120.705 1.00 52.33  ? 288 SER B O   1 
ATOM   1717 C  CB  . SER A 1 288 ? 118.530 99.751  119.093 1.00 52.33  ? 288 SER B CB  1 
ATOM   1718 O  OG  . SER A 1 288 ? 119.468 99.589  120.140 1.00 52.33  ? 288 SER B OG  1 
ATOM   1719 N  N   . PHE A 1 289 ? 116.033 97.718  120.058 1.00 53.71  ? 289 PHE B N   1 
ATOM   1720 C  CA  . PHE A 1 289 ? 115.439 97.134  121.259 1.00 53.71  ? 289 PHE B CA  1 
ATOM   1721 C  C   . PHE A 1 289 ? 115.686 95.637  121.396 1.00 53.71  ? 289 PHE B C   1 
ATOM   1722 O  O   . PHE A 1 289 ? 116.075 95.203  122.493 1.00 53.71  ? 289 PHE B O   1 
ATOM   1723 C  CB  . PHE A 1 289 ? 113.942 97.453  121.299 1.00 53.71  ? 289 PHE B CB  1 
ATOM   1724 C  CG  . PHE A 1 289 ? 113.256 96.966  122.539 1.00 53.71  ? 289 PHE B CG  1 
ATOM   1725 C  CD1 . PHE A 1 289 ? 113.429 97.622  123.744 1.00 53.71  ? 289 PHE B CD1 1 
ATOM   1726 C  CD2 . PHE A 1 289 ? 112.441 95.848  122.502 1.00 53.71  ? 289 PHE B CD2 1 
ATOM   1727 C  CE1 . PHE A 1 289 ? 112.800 97.176  124.887 1.00 53.71  ? 289 PHE B CE1 1 
ATOM   1728 C  CE2 . PHE A 1 289 ? 111.810 95.398  123.643 1.00 53.71  ? 289 PHE B CE2 1 
ATOM   1729 C  CZ  . PHE A 1 289 ? 111.990 96.063  124.836 1.00 53.71  ? 289 PHE B CZ  1 
ATOM   1730 N  N   . PRO A 1 290 ? 115.457 94.794  120.378 1.00 52.11  ? 290 PRO B N   1 
ATOM   1731 C  CA  . PRO A 1 290 ? 115.699 93.353  120.583 1.00 52.11  ? 290 PRO B CA  1 
ATOM   1732 C  C   . PRO A 1 290 ? 117.133 93.027  120.956 1.00 52.11  ? 290 PRO B C   1 
ATOM   1733 O  O   . PRO A 1 290 ? 117.367 92.176  121.826 1.00 52.11  ? 290 PRO B O   1 
ATOM   1734 C  CB  . PRO A 1 290 ? 115.310 92.739  119.231 1.00 52.11  ? 290 PRO B CB  1 
ATOM   1735 C  CG  . PRO A 1 290 ? 114.394 93.727  118.613 1.00 52.11  ? 290 PRO B CG  1 
ATOM   1736 C  CD  . PRO A 1 290 ? 114.914 95.061  119.035 1.00 52.11  ? 290 PRO B CD  1 
ATOM   1737 N  N   . ALA A 1 291 ? 118.103 93.693  120.328 1.00 52.70  ? 291 ALA B N   1 
ATOM   1738 C  CA  . ALA A 1 291 ? 119.502 93.448  120.655 1.00 52.70  ? 291 ALA B CA  1 
ATOM   1739 C  C   . ALA A 1 291 ? 119.798 93.835  122.097 1.00 52.70  ? 291 ALA B C   1 
ATOM   1740 O  O   . ALA A 1 291 ? 120.454 93.089  122.831 1.00 52.70  ? 291 ALA B O   1 
ATOM   1741 C  CB  . ALA A 1 291 ? 120.409 94.214  119.693 1.00 52.70  ? 291 ALA B CB  1 
ATOM   1742 N  N   . ALA A 1 292 ? 119.304 95.000  122.524 1.00 49.74  ? 292 ALA B N   1 
ATOM   1743 C  CA  . ALA A 1 292 ? 119.529 95.438  123.896 1.00 49.74  ? 292 ALA B CA  1 
ATOM   1744 C  C   . ALA A 1 292 ? 118.881 94.488  124.891 1.00 49.74  ? 292 ALA B C   1 
ATOM   1745 O  O   . ALA A 1 292 ? 119.470 94.172  125.928 1.00 49.74  ? 292 ALA B O   1 
ATOM   1746 C  CB  . ALA A 1 292 ? 119.002 96.859  124.088 1.00 49.74  ? 292 ALA B CB  1 
ATOM   1747 N  N   . LEU A 1 293 ? 117.669 94.015  124.592 1.00 48.88  ? 293 LEU B N   1 
ATOM   1748 C  CA  . LEU A 1 293 ? 116.978 93.107  125.503 1.00 48.88  ? 293 LEU B CA  1 
ATOM   1749 C  C   . LEU A 1 293 ? 117.712 91.776  125.623 1.00 48.88  ? 293 LEU B C   1 
ATOM   1750 O  O   . LEU A 1 293 ? 117.886 91.247  126.731 1.00 48.88  ? 293 LEU B O   1 
ATOM   1751 C  CB  . LEU A 1 293 ? 115.544 92.887  125.029 1.00 48.88  ? 293 LEU B CB  1 
ATOM   1752 C  CG  . LEU A 1 293 ? 114.654 92.064  125.958 1.00 48.88  ? 293 LEU B CG  1 
ATOM   1753 C  CD1 . LEU A 1 293 ? 114.349 92.841  127.228 1.00 48.88  ? 293 LEU B CD1 1 
ATOM   1754 C  CD2 . LEU A 1 293 ? 113.373 91.659  125.250 1.00 48.88  ? 293 LEU B CD2 1 
ATOM   1755 N  N   . ILE A 1 294 ? 118.144 91.212  124.492 1.00 49.24  ? 294 ILE B N   1 
ATOM   1756 C  CA  . ILE A 1 294 ? 118.868 89.945  124.533 1.00 49.24  ? 294 ILE B CA  1 
ATOM   1757 C  C   . ILE A 1 294 ? 120.184 90.110  125.281 1.00 49.24  ? 294 ILE B C   1 
ATOM   1758 O  O   . ILE A 1 294 ? 120.558 89.264  126.104 1.00 49.24  ? 294 ILE B O   1 
ATOM   1759 C  CB  . ILE A 1 294 ? 119.089 89.404  123.110 1.00 49.24  ? 294 ILE B CB  1 
ATOM   1760 C  CG1 . ILE A 1 294 ? 117.756 89.001  122.480 1.00 49.24  ? 294 ILE B CG1 1 
ATOM   1761 C  CG2 . ILE A 1 294 ? 120.026 88.214  123.135 1.00 49.24  ? 294 ILE B CG2 1 
ATOM   1762 C  CD1 . ILE A 1 294 ? 117.864 88.634  121.018 1.00 49.24  ? 294 ILE B CD1 1 
ATOM   1763 N  N   . ILE A 1 295 ? 120.906 91.202  125.011 1.00 48.86  ? 295 ILE B N   1 
ATOM   1764 C  CA  . ILE A 1 295 ? 122.160 91.452  125.711 1.00 48.86  ? 295 ILE B CA  1 
ATOM   1765 C  C   . ILE A 1 295 ? 121.913 91.597  127.204 1.00 48.86  ? 295 ILE B C   1 
ATOM   1766 O  O   . ILE A 1 295 ? 122.681 91.086  128.023 1.00 48.86  ? 295 ILE B O   1 
ATOM   1767 C  CB  . ILE A 1 295 ? 122.864 92.692  125.130 1.00 48.86  ? 295 ILE B CB  1 
ATOM   1768 C  CG1 . ILE A 1 295 ? 123.396 92.394  123.730 1.00 48.86  ? 295 ILE B CG1 1 
ATOM   1769 C  CG2 . ILE A 1 295 ? 124.004 93.131  126.029 1.00 48.86  ? 295 ILE B CG2 1 
ATOM   1770 C  CD1 . ILE A 1 295 ? 123.940 93.609  123.021 1.00 48.86  ? 295 ILE B CD1 1 
ATOM   1771 N  N   . LEU A 1 296 ? 120.836 92.287  127.584 1.00 47.90  ? 296 LEU B N   1 
ATOM   1772 C  CA  . LEU A 1 296 ? 120.533 92.477  128.998 1.00 47.90  ? 296 LEU B CA  1 
ATOM   1773 C  C   . LEU A 1 296 ? 120.256 91.147  129.685 1.00 47.90  ? 296 LEU B C   1 
ATOM   1774 O  O   . LEU A 1 296 ? 120.785 90.875  130.768 1.00 47.90  ? 296 LEU B O   1 
ATOM   1775 C  CB  . LEU A 1 296 ? 119.340 93.419  129.152 1.00 47.90  ? 296 LEU B CB  1 
ATOM   1776 C  CG  . LEU A 1 296 ? 119.152 94.061  130.523 1.00 47.90  ? 296 LEU B CG  1 
ATOM   1777 C  CD1 . LEU A 1 296 ? 120.324 94.963  130.841 1.00 47.90  ? 296 LEU B CD1 1 
ATOM   1778 C  CD2 . LEU A 1 296 ? 117.852 94.838  130.570 1.00 47.90  ? 296 LEU B CD2 1 
ATOM   1779 N  N   . LEU A 1 297 ? 119.432 90.300  129.066 1.00 50.28  ? 297 LEU B N   1 
ATOM   1780 C  CA  . LEU A 1 297 ? 119.108 89.017  129.683 1.00 50.28  ? 297 LEU B CA  1 
ATOM   1781 C  C   . LEU A 1 297 ? 120.346 88.135  129.801 1.00 50.28  ? 297 LEU B C   1 
ATOM   1782 O  O   . LEU A 1 297 ? 120.609 87.547  130.860 1.00 50.28  ? 297 LEU B O   1 
ATOM   1783 C  CB  . LEU A 1 297 ? 118.015 88.308  128.885 1.00 50.28  ? 297 LEU B CB  1 
ATOM   1784 C  CG  . LEU A 1 297 ? 116.594 88.844  129.067 1.00 50.28  ? 297 LEU B CG  1 
ATOM   1785 C  CD1 . LEU A 1 297 ? 115.578 87.860  128.515 1.00 50.28  ? 297 LEU B CD1 1 
ATOM   1786 C  CD2 . LEU A 1 297 ? 116.314 89.142  130.529 1.00 50.28  ? 297 LEU B CD2 1 
ATOM   1787 N  N   . LEU A 1 298 ? 121.130 88.041  128.724 1.00 51.24  ? 298 LEU B N   1 
ATOM   1788 C  CA  . LEU A 1 298 ? 122.326 87.205  128.763 1.00 51.24  ? 298 LEU B CA  1 
ATOM   1789 C  C   . LEU A 1 298 ? 123.349 87.745  129.754 1.00 51.24  ? 298 LEU B C   1 
ATOM   1790 O  O   . LEU A 1 298 ? 124.011 86.969  130.450 1.00 51.24  ? 298 LEU B O   1 
ATOM   1791 C  CB  . LEU A 1 298 ? 122.936 87.081  127.367 1.00 51.24  ? 298 LEU B CB  1 
ATOM   1792 C  CG  . LEU A 1 298 ? 122.412 85.969  126.454 1.00 51.24  ? 298 LEU B CG  1 
ATOM   1793 C  CD1 . LEU A 1 298 ? 122.727 84.611  127.057 1.00 51.24  ? 298 LEU B CD1 1 
ATOM   1794 C  CD2 . LEU A 1 298 ? 120.925 86.097  126.176 1.00 51.24  ? 298 LEU B CD2 1 
ATOM   1795 N  N   . SER A 1 299 ? 123.495 89.069  129.836 1.00 52.67  ? 299 SER B N   1 
ATOM   1796 C  CA  . SER A 1 299 ? 124.427 89.657  130.788 1.00 52.67  ? 299 SER B CA  1 
ATOM   1797 C  C   . SER A 1 299 ? 123.982 89.408  132.219 1.00 52.67  ? 299 SER B C   1 
ATOM   1798 O  O   . SER A 1 299 ? 124.814 89.140  133.092 1.00 52.67  ? 299 SER B O   1 
ATOM   1799 C  CB  . SER A 1 299 ? 124.570 91.154  130.524 1.00 52.67  ? 299 SER B CB  1 
ATOM   1800 O  OG  . SER A 1 299 ? 125.201 91.389  129.279 1.00 52.67  ? 299 SER B OG  1 
ATOM   1801 N  N   . TRP A 1 300 ? 122.677 89.498  132.486 1.00 54.40  ? 300 TRP B N   1 
ATOM   1802 C  CA  . TRP A 1 300 ? 122.183 89.183  133.821 1.00 54.40  ? 300 TRP B CA  1 
ATOM   1803 C  C   . TRP A 1 300 ? 122.483 87.736  134.178 1.00 54.40  ? 300 TRP B C   1 
ATOM   1804 O  O   . TRP A 1 300 ? 122.952 87.441  135.283 1.00 54.40  ? 300 TRP B O   1 
ATOM   1805 C  CB  . TRP A 1 300 ? 120.682 89.449  133.908 1.00 54.40  ? 300 TRP B CB  1 
ATOM   1806 C  CG  . TRP A 1 300 ? 120.052 88.813  135.103 1.00 54.40  ? 300 TRP B CG  1 
ATOM   1807 C  CD1 . TRP A 1 300 ? 120.294 89.110  136.409 1.00 54.40  ? 300 TRP B CD1 1 
ATOM   1808 C  CD2 . TRP A 1 300 ? 119.080 87.762  135.104 1.00 54.40  ? 300 TRP B CD2 1 
ATOM   1809 N  NE1 . TRP A 1 300 ? 119.531 88.314  137.226 1.00 54.40  ? 300 TRP B NE1 1 
ATOM   1810 C  CE2 . TRP A 1 300 ? 118.776 87.477  136.448 1.00 54.40  ? 300 TRP B CE2 1 
ATOM   1811 C  CE3 . TRP A 1 300 ? 118.437 87.035  134.099 1.00 54.40  ? 300 TRP B CE3 1 
ATOM   1812 C  CZ2 . TRP A 1 300 ? 117.858 86.497  136.814 1.00 54.40  ? 300 TRP B CZ2 1 
ATOM   1813 C  CZ3 . TRP A 1 300 ? 117.525 86.064  134.464 1.00 54.40  ? 300 TRP B CZ3 1 
ATOM   1814 C  CH2 . TRP A 1 300 ? 117.244 85.804  135.809 1.00 54.40  ? 300 TRP B CH2 1 
ATOM   1815 N  N   . ILE A 1 301 ? 122.233 86.818  133.241 1.00 53.25  ? 301 ILE B N   1 
ATOM   1816 C  CA  . ILE A 1 301 ? 122.497 85.405  133.502 1.00 53.25  ? 301 ILE B CA  1 
ATOM   1817 C  C   . ILE A 1 301 ? 123.982 85.183  133.767 1.00 53.25  ? 301 ILE B C   1 
ATOM   1818 O  O   . ILE A 1 301 ? 124.367 84.475  134.706 1.00 53.25  ? 301 ILE B O   1 
ATOM   1819 C  CB  . ILE A 1 301 ? 121.996 84.540  132.332 1.00 53.25  ? 301 ILE B CB  1 
ATOM   1820 C  CG1 . ILE A 1 301 ? 120.469 84.544  132.285 1.00 53.25  ? 301 ILE B CG1 1 
ATOM   1821 C  CG2 . ILE A 1 301 ? 122.520 83.121  132.455 1.00 53.25  ? 301 ILE B CG2 1 
ATOM   1822 C  CD1 . ILE A 1 301 ? 119.892 83.697  131.178 1.00 53.25  ? 301 ILE B CD1 1 
ATOM   1823 N  N   . TRP A 1 302 ? 124.837 85.793  132.945 1.00 53.24  ? 302 TRP B N   1 
ATOM   1824 C  CA  . TRP A 1 302 ? 126.277 85.603  133.080 1.00 53.24  ? 302 TRP B CA  1 
ATOM   1825 C  C   . TRP A 1 302 ? 126.792 86.171  134.397 1.00 53.24  ? 302 TRP B C   1 
ATOM   1826 O  O   . TRP A 1 302 ? 127.602 85.537  135.081 1.00 53.24  ? 302 TRP B O   1 
ATOM   1827 C  CB  . TRP A 1 302 ? 126.994 86.247  131.895 1.00 53.24  ? 302 TRP B CB  1 
ATOM   1828 C  CG  . TRP A 1 302 ? 128.447 86.474  132.121 1.00 53.24  ? 302 TRP B CG  1 
ATOM   1829 C  CD1 . TRP A 1 302 ? 129.066 87.670  132.317 1.00 53.24  ? 302 TRP B CD1 1 
ATOM   1830 C  CD2 . TRP A 1 302 ? 129.471 85.477  132.172 1.00 53.24  ? 302 TRP B CD2 1 
ATOM   1831 N  NE1 . TRP A 1 302 ? 130.415 87.482  132.487 1.00 53.24  ? 302 TRP B NE1 1 
ATOM   1832 C  CE2 . TRP A 1 302 ? 130.689 86.143  132.402 1.00 53.24  ? 302 TRP B CE2 1 
ATOM   1833 C  CE3 . TRP A 1 302 ? 129.476 84.086  132.044 1.00 53.24  ? 302 TRP B CE3 1 
ATOM   1834 C  CZ2 . TRP A 1 302 ? 131.899 85.466  132.509 1.00 53.24  ? 302 TRP B CZ2 1 
ATOM   1835 C  CZ3 . TRP A 1 302 ? 130.678 83.416  132.150 1.00 53.24  ? 302 TRP B CZ3 1 
ATOM   1836 C  CH2 . TRP A 1 302 ? 131.873 84.105  132.380 1.00 53.24  ? 302 TRP B CH2 1 
ATOM   1837 N  N   . LEU A 1 303 ? 126.336 87.369  134.768 1.00 54.57  ? 303 LEU B N   1 
ATOM   1838 C  CA  . LEU A 1 303 ? 126.771 87.968  136.024 1.00 54.57  ? 303 LEU B CA  1 
ATOM   1839 C  C   . LEU A 1 303 ? 126.285 87.158  137.216 1.00 54.57  ? 303 LEU B C   1 
ATOM   1840 O  O   . LEU A 1 303 ? 127.015 86.989  138.200 1.00 54.57  ? 303 LEU B O   1 
ATOM   1841 C  CB  . LEU A 1 303 ? 126.279 89.411  136.118 1.00 54.57  ? 303 LEU B CB  1 
ATOM   1842 C  CG  . LEU A 1 303 ? 126.991 90.425  135.224 1.00 54.57  ? 303 LEU B CG  1 
ATOM   1843 C  CD1 . LEU A 1 303 ? 126.390 91.806  135.402 1.00 54.57  ? 303 LEU B CD1 1 
ATOM   1844 C  CD2 . LEU A 1 303 ? 128.476 90.444  135.523 1.00 54.57  ? 303 LEU B CD2 1 
ATOM   1845 N  N   . GLN A 1 304 ? 125.051 86.650  137.152 1.00 62.85  ? 304 GLN B N   1 
ATOM   1846 C  CA  . GLN A 1 304 ? 124.546 85.814  138.234 1.00 62.85  ? 304 GLN B CA  1 
ATOM   1847 C  C   . GLN A 1 304 ? 125.360 84.534  138.365 1.00 62.85  ? 304 GLN B C   1 
ATOM   1848 O  O   . GLN A 1 304 ? 125.679 84.106  139.479 1.00 62.85  ? 304 GLN B O   1 
ATOM   1849 C  CB  . GLN A 1 304 ? 123.072 85.491  138.000 1.00 62.85  ? 304 GLN B CB  1 
ATOM   1850 C  CG  . GLN A 1 304 ? 122.314 85.130  139.259 1.00 62.85  ? 304 GLN B CG  1 
ATOM   1851 C  CD  . GLN A 1 304 ? 122.248 86.280  140.240 1.00 62.85  ? 304 GLN B CD  1 
ATOM   1852 O  OE1 . GLN A 1 304 ? 122.251 87.446  139.847 1.00 62.85  ? 304 GLN B OE1 1 
ATOM   1853 N  NE2 . GLN A 1 304 ? 122.190 85.958  141.526 1.00 62.85  ? 304 GLN B NE2 1 
ATOM   1854 N  N   . TRP A 1 305 ? 125.709 83.913  137.238 1.00 63.23  ? 305 TRP B N   1 
ATOM   1855 C  CA  . TRP A 1 305 ? 126.470 82.671  137.281 1.00 63.23  ? 305 TRP B CA  1 
ATOM   1856 C  C   . TRP A 1 305 ? 127.905 82.888  137.741 1.00 63.23  ? 305 TRP B C   1 
ATOM   1857 O  O   . TRP A 1 305 ? 128.467 82.026  138.425 1.00 63.23  ? 305 TRP B O   1 
ATOM   1858 C  CB  . TRP A 1 305 ? 126.459 82.004  135.906 1.00 63.23  ? 305 TRP B CB  1 
ATOM   1859 C  CG  . TRP A 1 305 ? 127.124 80.666  135.880 1.00 63.23  ? 305 TRP B CG  1 
ATOM   1860 C  CD1 . TRP A 1 305 ? 126.529 79.454  136.062 1.00 63.23  ? 305 TRP B CD1 1 
ATOM   1861 C  CD2 . TRP A 1 305 ? 128.513 80.402  135.657 1.00 63.23  ? 305 TRP B CD2 1 
ATOM   1862 N  NE1 . TRP A 1 305 ? 127.461 78.450  135.968 1.00 63.23  ? 305 TRP B NE1 1 
ATOM   1863 C  CE2 . TRP A 1 305 ? 128.688 79.007  135.719 1.00 63.23  ? 305 TRP B CE2 1 
ATOM   1864 C  CE3 . TRP A 1 305 ? 129.627 81.211  135.412 1.00 63.23  ? 305 TRP B CE3 1 
ATOM   1865 C  CZ2 . TRP A 1 305 ? 129.930 78.402  135.545 1.00 63.23  ? 305 TRP B CZ2 1 
ATOM   1866 C  CZ3 . TRP A 1 305 ? 130.858 80.608  135.240 1.00 63.23  ? 305 TRP B CZ3 1 
ATOM   1867 C  CH2 . TRP A 1 305 ? 131.000 79.218  135.307 1.00 63.23  ? 305 TRP B CH2 1 
ATOM   1868 N  N   . LEU A 1 306 ? 128.514 84.017  137.374 1.00 59.39  ? 306 LEU B N   1 
ATOM   1869 C  CA  . LEU A 1 306 ? 129.921 84.235  137.692 1.00 59.39  ? 306 LEU B CA  1 
ATOM   1870 C  C   . LEU A 1 306 ? 130.138 84.419  139.189 1.00 59.39  ? 306 LEU B C   1 
ATOM   1871 O  O   . LEU A 1 306 ? 131.066 83.836  139.762 1.00 59.39  ? 306 LEU B O   1 
ATOM   1872 C  CB  . LEU A 1 306 ? 130.448 85.444  136.923 1.00 59.39  ? 306 LEU B CB  1 
ATOM   1873 C  CG  . LEU A 1 306 ? 131.956 85.685  136.986 1.00 59.39  ? 306 LEU B CG  1 
ATOM   1874 C  CD1 . LEU A 1 306 ? 132.693 84.639  136.172 1.00 59.39  ? 306 LEU B CD1 1 
ATOM   1875 C  CD2 . LEU A 1 306 ? 132.293 87.082  136.497 1.00 59.39  ? 306 LEU B CD2 1 
ATOM   1876 N  N   . PHE A 1 307 ? 129.296 85.221  139.839 1.00 65.45  ? 307 PHE B N   1 
ATOM   1877 C  CA  . PHE A 1 307 ? 129.492 85.546  141.249 1.00 65.45  ? 307 PHE B CA  1 
ATOM   1878 C  C   . PHE A 1 307 ? 128.710 84.606  142.163 1.00 65.45  ? 307 PHE B C   1 
ATOM   1879 O  O   . PHE A 1 307 ? 129.295 83.923  143.009 1.00 65.45  ? 307 PHE B O   1 
ATOM   1880 C  CB  . PHE A 1 307 ? 129.101 87.005  141.506 1.00 65.45  ? 307 PHE B CB  1 
ATOM   1881 C  CG  . PHE A 1 307 ? 130.009 87.997  140.843 1.00 65.45  ? 307 PHE B CG  1 
ATOM   1882 C  CD1 . PHE A 1 307 ? 129.870 88.295  139.499 1.00 65.45  ? 307 PHE B CD1 1 
ATOM   1883 C  CD2 . PHE A 1 307 ? 131.010 88.624  141.562 1.00 65.45  ? 307 PHE B CD2 1 
ATOM   1884 C  CE1 . PHE A 1 307 ? 130.708 89.205  138.887 1.00 65.45  ? 307 PHE B CE1 1 
ATOM   1885 C  CE2 . PHE A 1 307 ? 131.851 89.534  140.956 1.00 65.45  ? 307 PHE B CE2 1 
ATOM   1886 C  CZ  . PHE A 1 307 ? 131.699 89.824  139.616 1.00 65.45  ? 307 PHE B CZ  1 
ATOM   1887 N  N   . LEU A 1 308 ? 127.392 84.566  142.007 1.00 68.80  ? 308 LEU B N   1 
ATOM   1888 C  CA  . LEU A 1 308 ? 126.559 83.653  142.771 1.00 68.80  ? 308 LEU B CA  1 
ATOM   1889 C  C   . LEU A 1 308 ? 126.354 82.368  141.972 1.00 68.80  ? 308 LEU B C   1 
ATOM   1890 O  O   . LEU A 1 308 ? 127.008 82.130  140.954 1.00 68.80  ? 308 LEU B O   1 
ATOM   1891 C  CB  . LEU A 1 308 ? 125.233 84.319  143.132 1.00 68.80  ? 308 LEU B CB  1 
ATOM   1892 C  CG  . LEU A 1 308 ? 125.186 85.083  144.456 1.00 68.80  ? 308 LEU B CG  1 
ATOM   1893 C  CD1 . LEU A 1 308 ? 125.906 86.413  144.339 1.00 68.80  ? 308 LEU B CD1 1 
ATOM   1894 C  CD2 . LEU A 1 308 ? 123.748 85.289  144.898 1.00 68.80  ? 308 LEU B CD2 1 
ATOM   1895 N  N   . GLY A 1 309 ? 125.444 81.520  142.433 1.00 81.08  ? 309 GLY B N   1 
ATOM   1896 C  CA  . GLY A 1 309 ? 125.067 80.308  141.722 1.00 81.08  ? 309 GLY B CA  1 
ATOM   1897 C  C   . GLY A 1 309 ? 123.665 80.455  141.159 1.00 81.08  ? 309 GLY B C   1 
ATOM   1898 O  O   . GLY A 1 309 ? 122.763 80.951  141.840 1.00 81.08  ? 309 GLY B O   1 
ATOM   1899 N  N   . PHE A 1 310 ? 123.489 80.025  139.913 1.00 88.94  ? 310 PHE B N   1 
ATOM   1900 C  CA  . PHE A 1 310 ? 122.197 80.125  139.239 1.00 88.94  ? 310 PHE B CA  1 
ATOM   1901 C  C   . PHE A 1 310 ? 121.356 78.920  139.638 1.00 88.94  ? 310 PHE B C   1 
ATOM   1902 O  O   . PHE A 1 310 ? 121.420 77.864  139.006 1.00 88.94  ? 310 PHE B O   1 
ATOM   1903 C  CB  . PHE A 1 310 ? 122.374 80.208  137.728 1.00 88.94  ? 310 PHE B CB  1 
ATOM   1904 C  CG  . PHE A 1 310 ? 121.206 80.828  137.020 1.00 88.94  ? 310 PHE B CG  1 
ATOM   1905 C  CD1 . PHE A 1 310 ? 120.813 82.124  137.309 1.00 88.94  ? 310 PHE B CD1 1 
ATOM   1906 C  CD2 . PHE A 1 310 ? 120.494 80.114  136.071 1.00 88.94  ? 310 PHE B CD2 1 
ATOM   1907 C  CE1 . PHE A 1 310 ? 119.737 82.697  136.664 1.00 88.94  ? 310 PHE B CE1 1 
ATOM   1908 C  CE2 . PHE A 1 310 ? 119.416 80.683  135.422 1.00 88.94  ? 310 PHE B CE2 1 
ATOM   1909 C  CZ  . PHE A 1 310 ? 119.037 81.976  135.719 1.00 88.94  ? 310 PHE B CZ  1 
ATOM   1910 N  N   . ASN A 1 311 ? 120.560 79.081  140.693 1.00 105.01 ? 311 ASN B N   1 
ATOM   1911 C  CA  . ASN A 1 311 ? 119.677 78.023  141.176 1.00 105.01 ? 311 ASN B CA  1 
ATOM   1912 C  C   . ASN A 1 311 ? 118.389 78.081  140.366 1.00 105.01 ? 311 ASN B C   1 
ATOM   1913 O  O   . ASN A 1 311 ? 117.528 78.931  140.604 1.00 105.01 ? 311 ASN B O   1 
ATOM   1914 C  CB  . ASN A 1 311 ? 119.409 78.181  142.668 1.00 105.01 ? 311 ASN B CB  1 
ATOM   1915 C  CG  . ASN A 1 311 ? 120.658 77.999  143.505 1.00 105.01 ? 311 ASN B CG  1 
ATOM   1916 O  OD1 . ASN A 1 311 ? 121.734 77.712  142.981 1.00 105.01 ? 311 ASN B OD1 1 
ATOM   1917 N  ND2 . ASN A 1 311 ? 120.522 78.165  144.816 1.00 105.01 ? 311 ASN B ND2 1 
ATOM   1918 N  N   . PHE A 1 312 ? 118.260 77.172  139.397 1.00 121.19 ? 312 PHE B N   1 
ATOM   1919 C  CA  . PHE A 1 312 ? 117.055 77.134  138.576 1.00 121.19 ? 312 PHE B CA  1 
ATOM   1920 C  C   . PHE A 1 312 ? 115.827 76.776  139.402 1.00 121.19 ? 312 PHE B C   1 
ATOM   1921 O  O   . PHE A 1 312 ? 114.724 77.253  139.113 1.00 121.19 ? 312 PHE B O   1 
ATOM   1922 C  CB  . PHE A 1 312 ? 117.234 76.142  137.427 1.00 121.19 ? 312 PHE B CB  1 
ATOM   1923 C  CG  . PHE A 1 312 ? 116.276 76.352  136.291 1.00 121.19 ? 312 PHE B CG  1 
ATOM   1924 C  CD1 . PHE A 1 312 ? 116.310 77.518  135.545 1.00 121.19 ? 312 PHE B CD1 1 
ATOM   1925 C  CD2 . PHE A 1 312 ? 115.341 75.383  135.967 1.00 121.19 ? 312 PHE B CD2 1 
ATOM   1926 C  CE1 . PHE A 1 312 ? 115.430 77.714  134.498 1.00 121.19 ? 312 PHE B CE1 1 
ATOM   1927 C  CE2 . PHE A 1 312 ? 114.458 75.572  134.921 1.00 121.19 ? 312 PHE B CE2 1 
ATOM   1928 C  CZ  . PHE A 1 312 ? 114.503 76.739  134.186 1.00 121.19 ? 312 PHE B CZ  1 
ATOM   1929 N  N   . LYS A 1 313 ? 115.996 75.934  140.425 1.00 123.30 ? 313 LYS B N   1 
ATOM   1930 C  CA  . LYS A 1 313 ? 114.876 75.591  141.295 1.00 123.30 ? 313 LYS B CA  1 
ATOM   1931 C  C   . LYS A 1 313 ? 114.376 76.812  142.057 1.00 123.30 ? 313 LYS B C   1 
ATOM   1932 O  O   . LYS A 1 313 ? 113.164 77.000  142.213 1.00 123.30 ? 313 LYS B O   1 
ATOM   1933 C  CB  . LYS A 1 313 ? 115.285 74.482  142.264 1.00 123.30 ? 313 LYS B CB  1 
ATOM   1934 C  CG  . LYS A 1 313 ? 116.203 73.431  141.659 1.00 123.30 ? 313 LYS B CG  1 
ATOM   1935 C  CD  . LYS A 1 313 ? 115.525 72.691  140.516 1.00 123.30 ? 313 LYS B CD  1 
ATOM   1936 C  CE  . LYS A 1 313 ? 116.535 71.909  139.690 1.00 123.30 ? 313 LYS B CE  1 
ATOM   1937 N  NZ  . LYS A 1 313 ? 115.925 71.343  138.456 1.00 123.30 ? 313 LYS B NZ  1 
ATOM   1938 N  N   . GLU A 1 314 ? 115.294 77.652  142.541 1.00 119.06 ? 314 GLU B N   1 
ATOM   1939 C  CA  . GLU A 1 314 ? 114.900 78.859  143.257 1.00 119.06 ? 314 GLU B CA  1 
ATOM   1940 C  C   . GLU A 1 314 ? 114.188 79.860  142.358 1.00 119.06 ? 314 GLU B C   1 
ATOM   1941 O  O   . GLU A 1 314 ? 113.447 80.709  142.863 1.00 119.06 ? 314 GLU B O   1 
ATOM   1942 C  CB  . GLU A 1 314 ? 116.124 79.514  143.899 1.00 119.06 ? 314 GLU B CB  1 
ATOM   1943 N  N   . MET A 1 315 ? 114.410 79.793  141.043 1.00 119.65 ? 315 MET B N   1 
ATOM   1944 C  CA  . MET A 1 315 ? 113.693 80.672  140.126 1.00 119.65 ? 315 MET B CA  1 
ATOM   1945 C  C   . MET A 1 315 ? 112.200 80.364  140.128 1.00 119.65 ? 315 MET B C   1 
ATOM   1946 O  O   . MET A 1 315 ? 111.373 81.256  140.344 1.00 119.65 ? 315 MET B O   1 
ATOM   1947 C  CB  . MET A 1 315 ? 114.273 80.536  138.717 1.00 119.65 ? 315 MET B CB  1 
ATOM   1948 C  CG  . MET A 1 315 ? 113.811 81.603  137.740 1.00 119.65 ? 315 MET B CG  1 
ATOM   1949 S  SD  . MET A 1 315 ? 113.886 81.043  136.027 1.00 119.65 ? 315 MET B SD  1 
ATOM   1950 C  CE  . MET A 1 315 ? 113.874 82.606  135.153 1.00 119.65 ? 315 MET B CE  1 
ATOM   1951 N  N   . PHE A 1 316 ? 111.850 79.093  139.922 1.00 123.42 ? 316 PHE B N   1 
ATOM   1952 C  CA  . PHE A 1 316 ? 110.471 78.590  139.828 1.00 123.42 ? 316 PHE B CA  1 
ATOM   1953 C  C   . PHE A 1 316 ? 109.448 79.610  139.328 1.00 123.42 ? 316 PHE B C   1 
ATOM   1954 O  O   . PHE A 1 316 ? 109.621 80.208  138.265 1.00 123.42 ? 316 PHE B O   1 
ATOM   1955 C  CB  . PHE A 1 316 ? 110.022 78.027  141.185 1.00 123.42 ? 316 PHE B CB  1 
ATOM   1956 C  CG  . PHE A 1 316 ? 109.584 79.072  142.175 1.00 123.42 ? 316 PHE B CG  1 
ATOM   1957 C  CD1 . PHE A 1 316 ? 110.513 79.742  142.953 1.00 123.42 ? 316 PHE B CD1 1 
ATOM   1958 C  CD2 . PHE A 1 316 ? 108.241 79.365  142.346 1.00 123.42 ? 316 PHE B CD2 1 
ATOM   1959 C  CE1 . PHE A 1 316 ? 110.114 80.696  143.869 1.00 123.42 ? 316 PHE B CE1 1 
ATOM   1960 C  CE2 . PHE A 1 316 ? 107.835 80.319  143.260 1.00 123.42 ? 316 PHE B CE2 1 
ATOM   1961 C  CZ  . PHE A 1 316 ? 108.773 80.984  144.023 1.00 123.42 ? 316 PHE B CZ  1 
ATOM   1962 N  N   . THR A 1 321 ? 104.606 81.541  151.090 1.00 112.41 ? 321 THR B N   1 
ATOM   1963 C  CA  . THR A 1 321 ? 105.736 81.040  151.864 1.00 112.41 ? 321 THR B CA  1 
ATOM   1964 C  C   . THR A 1 321 ? 106.952 81.944  151.702 1.00 112.41 ? 321 THR B C   1 
ATOM   1965 O  O   . THR A 1 321 ? 107.667 81.866  150.704 1.00 112.41 ? 321 THR B O   1 
ATOM   1966 C  CB  . THR A 1 321 ? 106.114 79.606  151.449 1.00 112.41 ? 321 THR B CB  1 
ATOM   1967 N  N   . LYS A 1 322 ? 107.182 82.804  152.693 1.00 114.54 ? 322 LYS B N   1 
ATOM   1968 C  CA  . LYS A 1 322 ? 108.291 83.745  152.673 1.00 114.54 ? 322 LYS B CA  1 
ATOM   1969 C  C   . LYS A 1 322 ? 109.134 83.572  153.927 1.00 114.54 ? 322 LYS B C   1 
ATOM   1970 O  O   . LYS A 1 322 ? 108.600 83.400  155.026 1.00 114.54 ? 322 LYS B O   1 
ATOM   1971 C  CB  . LYS A 1 322 ? 107.792 85.192  152.573 1.00 114.54 ? 322 LYS B CB  1 
ATOM   1972 N  N   . THR A 1 323 ? 110.452 83.618  153.755 1.00 116.55 ? 323 THR B N   1 
ATOM   1973 C  CA  . THR A 1 323 ? 111.366 83.504  154.878 1.00 116.55 ? 323 THR B CA  1 
ATOM   1974 C  C   . THR A 1 323 ? 111.509 84.849  155.587 1.00 116.55 ? 323 THR B C   1 
ATOM   1975 O  O   . THR A 1 323 ? 111.005 85.881  155.137 1.00 116.55 ? 323 THR B O   1 
ATOM   1976 C  CB  . THR A 1 323 ? 112.732 83.002  154.416 1.00 116.55 ? 323 THR B CB  1 
ATOM   1977 O  OG1 . THR A 1 323 ? 113.531 82.668  155.559 1.00 116.55 ? 323 THR B OG1 1 
ATOM   1978 C  CG2 . THR A 1 323 ? 113.446 84.072  153.608 1.00 116.55 ? 323 THR B CG2 1 
ATOM   1979 N  N   . VAL A 1 324 ? 112.213 84.825  156.721 1.00 114.93 ? 324 VAL B N   1 
ATOM   1980 C  CA  . VAL A 1 324 ? 112.410 86.042  157.503 1.00 114.93 ? 324 VAL B CA  1 
ATOM   1981 C  C   . VAL A 1 324 ? 113.247 87.050  156.725 1.00 114.93 ? 324 VAL B C   1 
ATOM   1982 O  O   . VAL A 1 324 ? 112.986 88.259  156.768 1.00 114.93 ? 324 VAL B O   1 
ATOM   1983 C  CB  . VAL A 1 324 ? 113.049 85.705  158.863 1.00 114.93 ? 324 VAL B CB  1 
ATOM   1984 C  CG1 . VAL A 1 324 ? 113.092 86.938  159.751 1.00 114.93 ? 324 VAL B CG1 1 
ATOM   1985 C  CG2 . VAL A 1 324 ? 112.284 84.580  159.541 1.00 114.93 ? 324 VAL B CG2 1 
ATOM   1986 N  N   . GLN A 1 325 ? 114.268 86.573  156.010 1.00 115.77 ? 325 GLN B N   1 
ATOM   1987 C  CA  . GLN A 1 325 ? 115.123 87.474  155.243 1.00 115.77 ? 325 GLN B CA  1 
ATOM   1988 C  C   . GLN A 1 325 ? 114.340 88.176  154.140 1.00 115.77 ? 325 GLN B C   1 
ATOM   1989 O  O   . GLN A 1 325 ? 114.542 89.371  153.887 1.00 115.77 ? 325 GLN B O   1 
ATOM   1990 C  CB  . GLN A 1 325 ? 116.303 86.699  154.656 1.00 115.77 ? 325 GLN B CB  1 
ATOM   1991 C  CG  . GLN A 1 325 ? 117.328 87.566  153.942 1.00 115.77 ? 325 GLN B CG  1 
ATOM   1992 C  CD  . GLN A 1 325 ? 118.326 88.190  154.898 1.00 115.77 ? 325 GLN B CD  1 
ATOM   1993 O  OE1 . GLN A 1 325 ? 118.359 87.858  156.083 1.00 115.77 ? 325 GLN B OE1 1 
ATOM   1994 N  NE2 . GLN A 1 325 ? 119.148 89.100  154.386 1.00 115.77 ? 325 GLN B NE2 1 
ATOM   1995 N  N   . GLN A 1 326 ? 113.449 87.446  153.464 1.00 113.69 ? 326 GLN B N   1 
ATOM   1996 C  CA  . GLN A 1 326 ? 112.631 88.056  152.420 1.00 113.69 ? 326 GLN B CA  1 
ATOM   1997 C  C   . GLN A 1 326 ? 111.713 89.127  152.993 1.00 113.69 ? 326 GLN B C   1 
ATOM   1998 O  O   . GLN A 1 326 ? 111.569 90.211  152.413 1.00 113.69 ? 326 GLN B O   1 
ATOM   1999 C  CB  . GLN A 1 326 ? 111.824 86.981  151.692 1.00 113.69 ? 326 GLN B CB  1 
ATOM   2000 C  CG  . GLN A 1 326 ? 112.645 86.152  150.716 1.00 113.69 ? 326 GLN B CG  1 
ATOM   2001 C  CD  . GLN A 1 326 ? 112.004 84.816  150.398 1.00 113.69 ? 326 GLN B CD  1 
ATOM   2002 O  OE1 . GLN A 1 326 ? 110.948 84.479  150.933 1.00 113.69 ? 326 GLN B OE1 1 
ATOM   2003 N  NE2 . GLN A 1 326 ? 112.642 84.047  149.524 1.00 113.69 ? 326 GLN B NE2 1 
ATOM   2004 N  N   . LYS A 1 327 ? 111.088 88.848  154.139 1.00 114.03 ? 327 LYS B N   1 
ATOM   2005 C  CA  . LYS A 1 327 ? 110.247 89.853  154.779 1.00 114.03 ? 327 LYS B CA  1 
ATOM   2006 C  C   . LYS A 1 327 ? 111.064 91.074  155.175 1.00 114.03 ? 327 LYS B C   1 
ATOM   2007 O  O   . LYS A 1 327 ? 110.620 92.214  154.994 1.00 114.03 ? 327 LYS B O   1 
ATOM   2008 C  CB  . LYS A 1 327 ? 109.548 89.253  155.998 1.00 114.03 ? 327 LYS B CB  1 
ATOM   2009 C  CG  . LYS A 1 327 ? 108.675 88.049  155.684 1.00 114.03 ? 327 LYS B CG  1 
ATOM   2010 C  CD  . LYS A 1 327 ? 107.901 87.593  156.909 1.00 114.03 ? 327 LYS B CD  1 
ATOM   2011 C  CE  . LYS A 1 327 ? 107.447 86.150  156.766 1.00 114.03 ? 327 LYS B CE  1 
ATOM   2012 N  NZ  . LYS A 1 327 ? 108.588 85.199  156.853 1.00 114.03 ? 327 LYS B NZ  1 
ATOM   2013 N  N   . ALA A 1 328 ? 112.269 90.855  155.707 1.00 112.62 ? 328 ALA B N   1 
ATOM   2014 C  CA  . ALA A 1 328 ? 113.114 91.970  156.118 1.00 112.62 ? 328 ALA B CA  1 
ATOM   2015 C  C   . ALA A 1 328 ? 113.508 92.839  154.930 1.00 112.62 ? 328 ALA B C   1 
ATOM   2016 O  O   . ALA A 1 328 ? 113.448 94.072  155.009 1.00 112.62 ? 328 ALA B O   1 
ATOM   2017 C  CB  . ALA A 1 328 ? 114.358 91.447  156.835 1.00 112.62 ? 328 ALA B CB  1 
ATOM   2018 N  N   . CYS A 1 329 ? 113.908 92.220  153.816 1.00 107.71 ? 329 CYS B N   1 
ATOM   2019 C  CA  . CYS A 1 329 ? 114.327 93.016  152.666 1.00 107.71 ? 329 CYS B CA  1 
ATOM   2020 C  C   . CYS A 1 329 ? 113.143 93.732  152.029 1.00 107.71 ? 329 CYS B C   1 
ATOM   2021 O  O   . CYS A 1 329 ? 113.278 94.872  151.567 1.00 107.71 ? 329 CYS B O   1 
ATOM   2022 C  CB  . CYS A 1 329 ? 115.050 92.146  151.637 1.00 107.71 ? 329 CYS B CB  1 
ATOM   2023 S  SG  . CYS A 1 329 ? 114.064 90.862  150.851 1.00 107.71 ? 329 CYS B SG  1 
ATOM   2024 N  N   . ALA A 1 330 ? 111.972 93.087  151.998 1.00 105.49 ? 330 ALA B N   1 
ATOM   2025 C  CA  . ALA A 1 330 ? 110.779 93.766  151.506 1.00 105.49 ? 330 ALA B CA  1 
ATOM   2026 C  C   . ALA A 1 330 ? 110.435 94.965  152.379 1.00 105.49 ? 330 ALA B C   1 
ATOM   2027 O  O   . ALA A 1 330 ? 110.069 96.031  151.870 1.00 105.49 ? 330 ALA B O   1 
ATOM   2028 C  CB  . ALA A 1 330 ? 109.605 92.790  151.444 1.00 105.49 ? 330 ALA B CB  1 
ATOM   2029 N  N   . GLU A 1 331 ? 110.559 94.810  153.700 1.00 103.51 ? 331 GLU B N   1 
ATOM   2030 C  CA  . GLU A 1 331 ? 110.313 95.923  154.609 1.00 103.51 ? 331 GLU B CA  1 
ATOM   2031 C  C   . GLU A 1 331 ? 111.307 97.051  154.356 1.00 103.51 ? 331 GLU B C   1 
ATOM   2032 O  O   . GLU A 1 331 ? 110.932 98.227  154.340 1.00 103.51 ? 331 GLU B O   1 
ATOM   2033 C  CB  . GLU A 1 331 ? 110.398 95.421  156.054 1.00 103.51 ? 331 GLU B CB  1 
ATOM   2034 C  CG  . GLU A 1 331 ? 110.362 96.462  157.181 1.00 103.51 ? 331 GLU B CG  1 
ATOM   2035 C  CD  . GLU A 1 331 ? 109.452 97.647  156.904 1.00 103.51 ? 331 GLU B CD  1 
ATOM   2036 O  OE1 . GLU A 1 331 ? 109.964 98.767  156.701 1.00 103.51 ? 331 GLU B OE1 1 
ATOM   2037 O  OE2 . GLU A 1 331 ? 108.218 97.455  156.890 1.00 103.51 ? 331 GLU B OE2 1 
ATOM   2038 N  N   . VAL A 1 332 ? 112.579 96.707  154.134 1.00 100.19 ? 332 VAL B N   1 
ATOM   2039 C  CA  . VAL A 1 332 ? 113.598 97.725  153.881 1.00 100.19 ? 332 VAL B CA  1 
ATOM   2040 C  C   . VAL A 1 332 ? 113.282 98.494  152.602 1.00 100.19 ? 332 VAL B C   1 
ATOM   2041 O  O   . VAL A 1 332 ? 113.358 99.730  152.562 1.00 100.19 ? 332 VAL B O   1 
ATOM   2042 C  CB  . VAL A 1 332 ? 114.995 97.083  153.821 1.00 100.19 ? 332 VAL B CB  1 
ATOM   2043 C  CG1 . VAL A 1 332 ? 116.007 98.069  153.264 1.00 100.19 ? 332 VAL B CG1 1 
ATOM   2044 C  CG2 . VAL A 1 332 ? 115.418 96.614  155.202 1.00 100.19 ? 332 VAL B CG2 1 
ATOM   2045 N  N   . ILE A 1 333 ? 112.927 97.772  151.536 1.00 94.54  ? 333 ILE B N   1 
ATOM   2046 C  CA  . ILE A 1 333 ? 112.580 98.430  150.278 1.00 94.54  ? 333 ILE B CA  1 
ATOM   2047 C  C   . ILE A 1 333 ? 111.371 99.337  150.467 1.00 94.54  ? 333 ILE B C   1 
ATOM   2048 O  O   . ILE A 1 333 ? 111.355 100.483 150.000 1.00 94.54  ? 333 ILE B O   1 
ATOM   2049 C  CB  . ILE A 1 333 ? 112.332 97.386  149.175 1.00 94.54  ? 333 ILE B CB  1 
ATOM   2050 C  CG1 . ILE A 1 333 ? 113.600 96.581  148.905 1.00 94.54  ? 333 ILE B CG1 1 
ATOM   2051 C  CG2 . ILE A 1 333 ? 111.876 98.065  147.900 1.00 94.54  ? 333 ILE B CG2 1 
ATOM   2052 C  CD1 . ILE A 1 333 ? 114.682 97.387  148.248 1.00 94.54  ? 333 ILE B CD1 1 
ATOM   2053 N  N   . LYS A 1 334 ? 110.346 98.844  151.164 1.00 96.45  ? 334 LYS B N   1 
ATOM   2054 C  CA  . LYS A 1 334 ? 109.147 99.643  151.383 1.00 96.45  ? 334 LYS B CA  1 
ATOM   2055 C  C   . LYS A 1 334 ? 109.466 100.909 152.165 1.00 96.45  ? 334 LYS B C   1 
ATOM   2056 O  O   . LYS A 1 334 ? 108.979 101.996 151.833 1.00 96.45  ? 334 LYS B O   1 
ATOM   2057 C  CB  . LYS A 1 334 ? 108.094 98.809  152.113 1.00 96.45  ? 334 LYS B CB  1 
ATOM   2058 C  CG  . LYS A 1 334 ? 106.663 99.258  151.878 1.00 96.45  ? 334 LYS B CG  1 
ATOM   2059 C  CD  . LYS A 1 334 ? 105.674 98.234  152.414 1.00 96.45  ? 334 LYS B CD  1 
ATOM   2060 C  CE  . LYS A 1 334 ? 106.121 97.684  153.761 1.00 96.45  ? 334 LYS B CE  1 
ATOM   2061 N  NZ  . LYS A 1 334 ? 105.366 96.460  154.144 1.00 96.45  ? 334 LYS B NZ  1 
ATOM   2062 N  N   . GLN A 1 335 ? 110.292 100.793 153.208 1.00 96.71  ? 335 GLN B N   1 
ATOM   2063 C  CA  . GLN A 1 335 ? 110.561 101.960 154.038 1.00 96.71  ? 335 GLN B CA  1 
ATOM   2064 C  C   . GLN A 1 335 ? 111.472 102.953 153.328 1.00 96.71  ? 335 GLN B C   1 
ATOM   2065 O  O   . GLN A 1 335 ? 111.340 104.160 153.543 1.00 96.71  ? 335 GLN B O   1 
ATOM   2066 C  CB  . GLN A 1 335 ? 111.113 101.535 155.407 1.00 96.71  ? 335 GLN B CB  1 
ATOM   2067 C  CG  . GLN A 1 335 ? 112.442 100.794 155.449 1.00 96.71  ? 335 GLN B CG  1 
ATOM   2068 C  CD  . GLN A 1 335 ? 113.641 101.687 155.220 1.00 96.71  ? 335 GLN B CD  1 
ATOM   2069 O  OE1 . GLN A 1 335 ? 113.771 102.743 155.837 1.00 96.71  ? 335 GLN B OE1 1 
ATOM   2070 N  NE2 . GLN A 1 335 ? 114.546 101.246 154.359 1.00 96.71  ? 335 GLN B NE2 1 
ATOM   2071 N  N   . GLU A 1 336 ? 112.360 102.487 152.443 1.00 92.34  ? 336 GLU B N   1 
ATOM   2072 C  CA  . GLU A 1 336 ? 113.039 103.429 151.555 1.00 92.34  ? 336 GLU B CA  1 
ATOM   2073 C  C   . GLU A 1 336 ? 112.043 104.126 150.636 1.00 92.34  ? 336 GLU B C   1 
ATOM   2074 O  O   . GLU A 1 336 ? 112.175 105.324 150.353 1.00 92.34  ? 336 GLU B O   1 
ATOM   2075 C  CB  . GLU A 1 336 ? 114.117 102.730 150.727 1.00 92.34  ? 336 GLU B CB  1 
ATOM   2076 C  CG  . GLU A 1 336 ? 115.322 102.263 151.515 1.00 92.34  ? 336 GLU B CG  1 
ATOM   2077 C  CD  . GLU A 1 336 ? 116.390 101.652 150.633 1.00 92.34  ? 336 GLU B CD  1 
ATOM   2078 O  OE1 . GLU A 1 336 ? 116.145 101.505 149.418 1.00 92.34  ? 336 GLU B OE1 1 
ATOM   2079 O  OE2 . GLU A 1 336 ? 117.476 101.320 151.154 1.00 92.34  ? 336 GLU B OE2 1 
ATOM   2080 N  N   . TYR A 1 337 ? 111.041 103.387 150.154 1.00 85.96  ? 337 TYR B N   1 
ATOM   2081 C  CA  . TYR A 1 337 ? 110.040 103.990 149.282 1.00 85.96  ? 337 TYR B CA  1 
ATOM   2082 C  C   . TYR A 1 337 ? 109.274 105.095 150.000 1.00 85.96  ? 337 TYR B C   1 
ATOM   2083 O  O   . TYR A 1 337 ? 109.028 106.161 149.425 1.00 85.96  ? 337 TYR B O   1 
ATOM   2084 C  CB  . TYR A 1 337 ? 109.084 102.919 148.760 1.00 85.96  ? 337 TYR B CB  1 
ATOM   2085 C  CG  . TYR A 1 337 ? 108.101 103.427 147.733 1.00 85.96  ? 337 TYR B CG  1 
ATOM   2086 C  CD1 . TYR A 1 337 ? 108.541 104.000 146.549 1.00 85.96  ? 337 TYR B CD1 1 
ATOM   2087 C  CD2 . TYR A 1 337 ? 106.734 103.330 147.946 1.00 85.96  ? 337 TYR B CD2 1 
ATOM   2088 C  CE1 . TYR A 1 337 ? 107.648 104.464 145.607 1.00 85.96  ? 337 TYR B CE1 1 
ATOM   2089 C  CE2 . TYR A 1 337 ? 105.832 103.791 147.010 1.00 85.96  ? 337 TYR B CE2 1 
ATOM   2090 C  CZ  . TYR A 1 337 ? 106.294 104.357 145.842 1.00 85.96  ? 337 TYR B CZ  1 
ATOM   2091 O  OH  . TYR A 1 337 ? 105.397 104.819 144.907 1.00 85.96  ? 337 TYR B OH  1 
ATOM   2092 N  N   . GLN A 1 338 ? 108.884 104.862 151.257 1.00 90.12  ? 338 GLN B N   1 
ATOM   2093 C  CA  . GLN A 1 338 ? 108.260 105.949 152.012 1.00 90.12  ? 338 GLN B CA  1 
ATOM   2094 C  C   . GLN A 1 338 ? 109.260 107.052 152.340 1.00 90.12  ? 338 GLN B C   1 
ATOM   2095 O  O   . GLN A 1 338 ? 108.873 108.222 152.443 1.00 90.12  ? 338 GLN B O   1 
ATOM   2096 C  CB  . GLN A 1 338 ? 107.589 105.467 153.304 1.00 90.12  ? 338 GLN B CB  1 
ATOM   2097 C  CG  . GLN A 1 338 ? 106.287 104.693 153.119 1.00 90.12  ? 338 GLN B CG  1 
ATOM   2098 C  CD  . GLN A 1 338 ? 106.468 103.196 153.144 1.00 90.12  ? 338 GLN B CD  1 
ATOM   2099 O  OE1 . GLN A 1 338 ? 107.423 102.690 153.727 1.00 90.12  ? 338 GLN B OE1 1 
ATOM   2100 N  NE2 . GLN A 1 338 ? 105.550 102.475 152.511 1.00 90.12  ? 338 GLN B NE2 1 
ATOM   2101 N  N   . LYS A 1 339 ? 110.539 106.706 152.514 1.00 91.15  ? 339 LYS B N   1 
ATOM   2102 C  CA  . LYS A 1 339 ? 111.562 107.725 152.716 1.00 91.15  ? 339 LYS B CA  1 
ATOM   2103 C  C   . LYS A 1 339 ? 111.660 108.656 151.518 1.00 91.15  ? 339 LYS B C   1 
ATOM   2104 O  O   . LYS A 1 339 ? 112.007 109.833 151.672 1.00 91.15  ? 339 LYS B O   1 
ATOM   2105 C  CB  . LYS A 1 339 ? 112.914 107.063 152.986 1.00 91.15  ? 339 LYS B CB  1 
ATOM   2106 C  CG  . LYS A 1 339 ? 113.987 108.011 153.490 1.00 91.15  ? 339 LYS B CG  1 
ATOM   2107 C  CD  . LYS A 1 339 ? 115.073 107.261 154.243 1.00 91.15  ? 339 LYS B CD  1 
ATOM   2108 C  CE  . LYS A 1 339 ? 116.234 106.910 153.327 1.00 91.15  ? 339 LYS B CE  1 
ATOM   2109 N  NZ  . LYS A 1 339 ? 117.177 105.947 153.960 1.00 91.15  ? 339 LYS B NZ  1 
ATOM   2110 N  N   . LEU A 1 340 ? 111.366 108.148 150.318 1.00 84.76  ? 340 LEU B N   1 
ATOM   2111 C  CA  . LEU A 1 340 ? 111.305 109.019 149.149 1.00 84.76  ? 340 LEU B CA  1 
ATOM   2112 C  C   . LEU A 1 340 ? 110.224 110.080 149.313 1.00 84.76  ? 340 LEU B C   1 
ATOM   2113 O  O   . LEU A 1 340 ? 110.416 111.238 148.925 1.00 84.76  ? 340 LEU B O   1 
ATOM   2114 C  CB  . LEU A 1 340 ? 111.062 108.196 147.884 1.00 84.76  ? 340 LEU B CB  1 
ATOM   2115 C  CG  . LEU A 1 340 ? 112.305 107.596 147.227 1.00 84.76  ? 340 LEU B CG  1 
ATOM   2116 C  CD1 . LEU A 1 340 ? 111.992 107.149 145.813 1.00 84.76  ? 340 LEU B CD1 1 
ATOM   2117 C  CD2 . LEU A 1 340 ? 113.450 108.594 147.232 1.00 84.76  ? 340 LEU B CD2 1 
ATOM   2118 N  N   . GLY A 1 341 ? 109.084 109.704 149.885 1.00 82.50  ? 341 GLY B N   1 
ATOM   2119 C  CA  . GLY A 1 341 ? 108.034 110.648 150.179 1.00 82.50  ? 341 GLY B CA  1 
ATOM   2120 C  C   . GLY A 1 341 ? 106.830 110.492 149.275 1.00 82.50  ? 341 GLY B C   1 
ATOM   2121 O  O   . GLY A 1 341 ? 106.886 109.837 148.229 1.00 82.50  ? 341 GLY B O   1 
ATOM   2122 N  N   . PRO A 1 342 ? 105.709 111.091 149.669 1.00 76.27  ? 342 PRO B N   1 
ATOM   2123 C  CA  . PRO A 1 342 ? 104.506 111.024 148.835 1.00 76.27  ? 342 PRO B CA  1 
ATOM   2124 C  C   . PRO A 1 342 ? 104.687 111.788 147.534 1.00 76.27  ? 342 PRO B C   1 
ATOM   2125 O  O   . PRO A 1 342 ? 105.463 112.743 147.447 1.00 76.27  ? 342 PRO B O   1 
ATOM   2126 C  CB  . PRO A 1 342 ? 103.428 111.668 149.713 1.00 76.27  ? 342 PRO B CB  1 
ATOM   2127 C  CG  . PRO A 1 342 ? 104.184 112.563 150.634 1.00 76.27  ? 342 PRO B CG  1 
ATOM   2128 C  CD  . PRO A 1 342 ? 105.495 111.879 150.894 1.00 76.27  ? 342 PRO B CD  1 
ATOM   2129 N  N   . ILE A 1 343 ? 103.952 111.349 146.511 1.00 70.62  ? 343 ILE B N   1 
ATOM   2130 C  CA  . ILE A 1 343 ? 104.069 111.952 145.190 1.00 70.62  ? 343 ILE B CA  1 
ATOM   2131 C  C   . ILE A 1 343 ? 103.566 113.391 145.230 1.00 70.62  ? 343 ILE B C   1 
ATOM   2132 O  O   . ILE A 1 343 ? 102.730 113.764 146.064 1.00 70.62  ? 343 ILE B O   1 
ATOM   2133 C  CB  . ILE A 1 343 ? 103.302 111.114 144.149 1.00 70.62  ? 343 ILE B CB  1 
ATOM   2134 C  CG1 . ILE A 1 343 ? 103.819 111.399 142.738 1.00 70.62  ? 343 ILE B CG1 1 
ATOM   2135 C  CG2 . ILE A 1 343 ? 101.806 111.370 144.241 1.00 70.62  ? 343 ILE B CG2 1 
ATOM   2136 C  CD1 . ILE A 1 343 ? 103.349 110.400 141.706 1.00 70.62  ? 343 ILE B CD1 1 
ATOM   2137 N  N   . ARG A 1 344 ? 104.095 114.215 144.331 1.00 66.60  ? 344 ARG B N   1 
ATOM   2138 C  CA  . ARG A 1 344 ? 103.763 115.629 144.259 1.00 66.60  ? 344 ARG B CA  1 
ATOM   2139 C  C   . ARG A 1 344 ? 103.142 115.953 142.906 1.00 66.60  ? 344 ARG B C   1 
ATOM   2140 O  O   . ARG A 1 344 ? 103.112 115.126 141.991 1.00 66.60  ? 344 ARG B O   1 
ATOM   2141 C  CB  . ARG A 1 344 ? 105.002 116.501 144.493 1.00 66.60  ? 344 ARG B CB  1 
ATOM   2142 C  CG  . ARG A 1 344 ? 105.262 116.835 145.950 1.00 66.60  ? 344 ARG B CG  1 
ATOM   2143 C  CD  . ARG A 1 344 ? 106.689 117.312 146.155 1.00 66.60  ? 344 ARG B CD  1 
ATOM   2144 N  NE  . ARG A 1 344 ? 107.655 116.424 145.518 1.00 66.60  ? 344 ARG B NE  1 
ATOM   2145 C  CZ  . ARG A 1 344 ? 108.733 116.835 144.864 1.00 66.60  ? 344 ARG B CZ  1 
ATOM   2146 N  NH1 . ARG A 1 344 ? 109.018 118.120 144.740 1.00 66.60  ? 344 ARG B NH1 1 
ATOM   2147 N  NH2 . ARG A 1 344 ? 109.544 115.933 144.321 1.00 66.60  ? 344 ARG B NH2 1 
ATOM   2148 N  N   . TYR A 1 345 ? 102.636 117.183 142.796 1.00 65.00  ? 345 TYR B N   1 
ATOM   2149 C  CA  . TYR A 1 345 ? 102.018 117.627 141.551 1.00 65.00  ? 345 TYR B CA  1 
ATOM   2150 C  C   . TYR A 1 345 ? 103.039 117.721 140.424 1.00 65.00  ? 345 TYR B C   1 
ATOM   2151 O  O   . TYR A 1 345 ? 102.744 117.357 139.278 1.00 65.00  ? 345 TYR B O   1 
ATOM   2152 C  CB  . TYR A 1 345 ? 101.328 118.972 141.769 1.00 65.00  ? 345 TYR B CB  1 
ATOM   2153 C  CG  . TYR A 1 345 ? 101.203 119.804 140.518 1.00 65.00  ? 345 TYR B CG  1 
ATOM   2154 C  CD1 . TYR A 1 345 ? 100.321 119.447 139.509 1.00 65.00  ? 345 TYR B CD1 1 
ATOM   2155 C  CD2 . TYR A 1 345 ? 101.965 120.950 140.348 1.00 65.00  ? 345 TYR B CD2 1 
ATOM   2156 C  CE1 . TYR A 1 345 ? 100.203 120.207 138.364 1.00 65.00  ? 345 TYR B CE1 1 
ATOM   2157 C  CE2 . TYR A 1 345 ? 101.854 121.716 139.208 1.00 65.00  ? 345 TYR B CE2 1 
ATOM   2158 C  CZ  . TYR A 1 345 ? 100.972 121.340 138.219 1.00 65.00  ? 345 TYR B CZ  1 
ATOM   2159 O  OH  . TYR A 1 345 ? 100.858 122.100 137.079 1.00 65.00  ? 345 TYR B OH  1 
ATOM   2160 N  N   . GLN A 1 346 ? 104.241 118.218 140.724 1.00 61.45  ? 346 GLN B N   1 
ATOM   2161 C  CA  . GLN A 1 346 ? 105.277 118.300 139.700 1.00 61.45  ? 346 GLN B CA  1 
ATOM   2162 C  C   . GLN A 1 346 ? 105.634 116.918 139.172 1.00 61.45  ? 346 GLN B C   1 
ATOM   2163 O  O   . GLN A 1 346 ? 105.776 116.725 137.958 1.00 61.45  ? 346 GLN B O   1 
ATOM   2164 C  CB  . GLN A 1 346 ? 106.515 118.999 140.259 1.00 61.45  ? 346 GLN B CB  1 
ATOM   2165 C  CG  . GLN A 1 346 ? 106.246 120.390 140.800 1.00 61.45  ? 346 GLN B CG  1 
ATOM   2166 C  CD  . GLN A 1 346 ? 106.118 120.413 142.307 1.00 61.45  ? 346 GLN B CD  1 
ATOM   2167 O  OE1 . GLN A 1 346 ? 106.909 119.796 143.018 1.00 61.45  ? 346 GLN B OE1 1 
ATOM   2168 N  NE2 . GLN A 1 346 ? 105.114 121.125 142.805 1.00 61.45  ? 346 GLN B NE2 1 
ATOM   2169 N  N   . GLU A 1 347 ? 105.767 115.939 140.067 1.00 64.08  ? 347 GLU B N   1 
ATOM   2170 C  CA  . GLU A 1 347 ? 106.105 114.588 139.634 1.00 64.08  ? 347 GLU B CA  1 
ATOM   2171 C  C   . GLU A 1 347 ? 105.012 113.995 138.753 1.00 64.08  ? 347 GLU B C   1 
ATOM   2172 O  O   . GLU A 1 347 ? 105.306 113.376 137.726 1.00 64.08  ? 347 GLU B O   1 
ATOM   2173 C  CB  . GLU A 1 347 ? 106.366 113.698 140.848 1.00 64.08  ? 347 GLU B CB  1 
ATOM   2174 C  CG  . GLU A 1 347 ? 107.524 114.167 141.712 1.00 64.08  ? 347 GLU B CG  1 
ATOM   2175 C  CD  . GLU A 1 347 ? 107.867 113.187 142.815 1.00 64.08  ? 347 GLU B CD  1 
ATOM   2176 O  OE1 . GLU A 1 347 ? 107.643 111.974 142.626 1.00 64.08  ? 347 GLU B OE1 1 
ATOM   2177 O  OE2 . GLU A 1 347 ? 108.363 113.630 143.872 1.00 64.08  ? 347 GLU B OE2 1 
ATOM   2178 N  N   . ILE A 1 348 ? 103.745 114.183 139.127 1.00 57.66  ? 348 ILE B N   1 
ATOM   2179 C  CA  . ILE A 1 348 ? 102.666 113.573 138.356 1.00 57.66  ? 348 ILE B CA  1 
ATOM   2180 C  C   . ILE A 1 348 ? 102.520 114.250 136.996 1.00 57.66  ? 348 ILE B C   1 
ATOM   2181 O  O   . ILE A 1 348 ? 102.272 113.582 135.985 1.00 57.66  ? 348 ILE B O   1 
ATOM   2182 C  CB  . ILE A 1 348 ? 101.346 113.573 139.154 1.00 57.66  ? 348 ILE B CB  1 
ATOM   2183 C  CG1 . ILE A 1 348 ? 100.305 112.696 138.459 1.00 57.66  ? 348 ILE B CG1 1 
ATOM   2184 C  CG2 . ILE A 1 348 ? 100.798 114.970 139.345 1.00 57.66  ? 348 ILE B CG2 1 
ATOM   2185 C  CD1 . ILE A 1 348 ? 100.634 111.224 138.482 1.00 57.66  ? 348 ILE B CD1 1 
ATOM   2186 N  N   . VAL A 1 349 ? 102.687 115.575 136.932 1.00 56.63  ? 349 VAL B N   1 
ATOM   2187 C  CA  . VAL A 1 349 ? 102.583 116.241 135.636 1.00 56.63  ? 349 VAL B CA  1 
ATOM   2188 C  C   . VAL A 1 349 ? 103.767 115.871 134.746 1.00 56.63  ? 349 VAL B C   1 
ATOM   2189 O  O   . VAL A 1 349 ? 103.612 115.684 133.530 1.00 56.63  ? 349 VAL B O   1 
ATOM   2190 C  CB  . VAL A 1 349 ? 102.431 117.766 135.807 1.00 56.63  ? 349 VAL B CB  1 
ATOM   2191 C  CG1 . VAL A 1 349 ? 103.707 118.407 136.316 1.00 56.63  ? 349 VAL B CG1 1 
ATOM   2192 C  CG2 . VAL A 1 349 ? 102.003 118.400 134.496 1.00 56.63  ? 349 VAL B CG2 1 
ATOM   2193 N  N   . THR A 1 350 ? 104.963 115.735 135.332 1.00 55.09  ? 350 THR B N   1 
ATOM   2194 C  CA  . THR A 1 350 ? 106.112 115.281 134.557 1.00 55.09  ? 350 THR B CA  1 
ATOM   2195 C  C   . THR A 1 350 ? 105.892 113.870 134.034 1.00 55.09  ? 350 THR B C   1 
ATOM   2196 O  O   . THR A 1 350 ? 106.224 113.569 132.884 1.00 55.09  ? 350 THR B O   1 
ATOM   2197 C  CB  . THR A 1 350 ? 107.380 115.342 135.408 1.00 55.09  ? 350 THR B CB  1 
ATOM   2198 O  OG1 . THR A 1 350 ? 107.631 116.697 135.796 1.00 55.09  ? 350 THR B OG1 1 
ATOM   2199 C  CG2 . THR A 1 350 ? 108.571 114.817 134.627 1.00 55.09  ? 350 THR B CG2 1 
ATOM   2200 N  N   . LEU A 1 351 ? 105.324 112.993 134.863 1.00 53.62  ? 351 LEU B N   1 
ATOM   2201 C  CA  . LEU A 1 351 ? 105.033 111.634 134.423 1.00 53.62  ? 351 LEU B CA  1 
ATOM   2202 C  C   . LEU A 1 351 ? 104.009 111.626 133.296 1.00 53.62  ? 351 LEU B C   1 
ATOM   2203 O  O   . LEU A 1 351 ? 104.135 110.852 132.343 1.00 53.62  ? 351 LEU B O   1 
ATOM   2204 C  CB  . LEU A 1 351 ? 104.544 110.797 135.604 1.00 53.62  ? 351 LEU B CB  1 
ATOM   2205 C  CG  . LEU A 1 351 ? 104.349 109.299 135.381 1.00 53.62  ? 351 LEU B CG  1 
ATOM   2206 C  CD1 . LEU A 1 351 ? 104.862 108.525 136.580 1.00 53.62  ? 351 LEU B CD1 1 
ATOM   2207 C  CD2 . LEU A 1 351 ? 102.884 108.983 135.137 1.00 53.62  ? 351 LEU B CD2 1 
ATOM   2208 N  N   . VAL A 1 352 ? 102.984 112.475 133.389 1.00 50.49  ? 352 VAL B N   1 
ATOM   2209 C  CA  . VAL A 1 352 ? 101.967 112.528 132.341 1.00 50.49  ? 352 VAL B CA  1 
ATOM   2210 C  C   . VAL A 1 352 ? 102.581 112.984 131.023 1.00 50.49  ? 352 VAL B C   1 
ATOM   2211 O  O   . VAL A 1 352 ? 102.348 112.384 129.965 1.00 50.49  ? 352 VAL B O   1 
ATOM   2212 C  CB  . VAL A 1 352 ? 100.803 113.438 132.767 1.00 50.49  ? 352 VAL B CB  1 
ATOM   2213 C  CG1 . VAL A 1 352 ? 99.964  113.821 131.561 1.00 50.49  ? 352 VAL B CG1 1 
ATOM   2214 C  CG2 . VAL A 1 352 ? 99.949  112.743 133.810 1.00 50.49  ? 352 VAL B CG2 1 
ATOM   2215 N  N   . LEU A 1 353 ? 103.383 114.051 131.065 1.00 46.99  ? 353 LEU B N   1 
ATOM   2216 C  CA  . LEU A 1 353 ? 104.014 114.533 129.839 1.00 46.99  ? 353 LEU B CA  1 
ATOM   2217 C  C   . LEU A 1 353 ? 105.004 113.512 129.289 1.00 46.99  ? 353 LEU B C   1 
ATOM   2218 O  O   . LEU A 1 353 ? 105.124 113.347 128.070 1.00 46.99  ? 353 LEU B O   1 
ATOM   2219 C  CB  . LEU A 1 353 ? 104.696 115.876 130.089 1.00 46.99  ? 353 LEU B CB  1 
ATOM   2220 C  CG  . LEU A 1 353 ? 103.737 117.058 130.242 1.00 46.99  ? 353 LEU B CG  1 
ATOM   2221 C  CD1 . LEU A 1 353 ? 104.478 118.320 130.630 1.00 46.99  ? 353 LEU B CD1 1 
ATOM   2222 C  CD2 . LEU A 1 353 ? 102.957 117.273 128.960 1.00 46.99  ? 353 LEU B CD2 1 
ATOM   2223 N  N   . PHE A 1 354 ? 105.716 112.811 130.172 1.00 48.97  ? 354 PHE B N   1 
ATOM   2224 C  CA  . PHE A 1 354 ? 106.644 111.776 129.734 1.00 48.97  ? 354 PHE B CA  1 
ATOM   2225 C  C   . PHE A 1 354 ? 105.909 110.623 129.061 1.00 48.97  ? 354 PHE B C   1 
ATOM   2226 O  O   . PHE A 1 354 ? 106.379 110.081 128.056 1.00 48.97  ? 354 PHE B O   1 
ATOM   2227 C  CB  . PHE A 1 354 ? 107.461 111.287 130.931 1.00 48.97  ? 354 PHE B CB  1 
ATOM   2228 C  CG  . PHE A 1 354 ? 108.255 110.043 130.666 1.00 48.97  ? 354 PHE B CG  1 
ATOM   2229 C  CD1 . PHE A 1 354 ? 109.072 109.944 129.556 1.00 48.97  ? 354 PHE B CD1 1 
ATOM   2230 C  CD2 . PHE A 1 354 ? 108.193 108.974 131.542 1.00 48.97  ? 354 PHE B CD2 1 
ATOM   2231 C  CE1 . PHE A 1 354 ? 109.802 108.800 129.319 1.00 48.97  ? 354 PHE B CE1 1 
ATOM   2232 C  CE2 . PHE A 1 354 ? 108.921 107.829 131.311 1.00 48.97  ? 354 PHE B CE2 1 
ATOM   2233 C  CZ  . PHE A 1 354 ? 109.727 107.742 130.199 1.00 48.97  ? 354 PHE B CZ  1 
ATOM   2234 N  N   . ILE A 1 355 ? 104.757 110.229 129.606 1.00 46.30  ? 355 ILE B N   1 
ATOM   2235 C  CA  . ILE A 1 355 ? 103.959 109.177 128.982 1.00 46.30  ? 355 ILE B CA  1 
ATOM   2236 C  C   . ILE A 1 355 ? 103.456 109.633 127.620 1.00 46.30  ? 355 ILE B C   1 
ATOM   2237 O  O   . ILE A 1 355 ? 103.455 108.863 126.651 1.00 46.30  ? 355 ILE B O   1 
ATOM   2238 C  CB  . ILE A 1 355 ? 102.800 108.762 129.906 1.00 46.30  ? 355 ILE B CB  1 
ATOM   2239 C  CG1 . ILE A 1 355 ? 103.334 108.049 131.148 1.00 46.30  ? 355 ILE B CG1 1 
ATOM   2240 C  CG2 . ILE A 1 355 ? 101.824 107.866 129.171 1.00 46.30  ? 355 ILE B CG2 1 
ATOM   2241 C  CD1 . ILE A 1 355 ? 104.181 106.843 130.841 1.00 46.30  ? 355 ILE B CD1 1 
ATOM   2242 N  N   . ILE A 1 356 ? 103.021 110.892 127.523 1.00 49.54  ? 356 ILE B N   1 
ATOM   2243 C  CA  . ILE A 1 356 ? 102.565 111.421 126.239 1.00 49.54  ? 356 ILE B CA  1 
ATOM   2244 C  C   . ILE A 1 356 ? 103.704 111.421 125.226 1.00 49.54  ? 356 ILE B C   1 
ATOM   2245 O  O   . ILE A 1 356 ? 103.498 111.145 124.039 1.00 49.54  ? 356 ILE B O   1 
ATOM   2246 C  CB  . ILE A 1 356 ? 101.964 112.827 126.422 1.00 49.54  ? 356 ILE B CB  1 
ATOM   2247 C  CG1 . ILE A 1 356 ? 100.676 112.751 127.240 1.00 49.54  ? 356 ILE B CG1 1 
ATOM   2248 C  CG2 . ILE A 1 356 ? 101.691 113.474 125.077 1.00 49.54  ? 356 ILE B CG2 1 
ATOM   2249 C  CD1 . ILE A 1 356 ? 99.592  111.927 126.589 1.00 49.54  ? 356 ILE B CD1 1 
ATOM   2250 N  N   . MET A 1 357 ? 104.922 111.729 125.677 1.00 54.12  ? 357 MET B N   1 
ATOM   2251 C  CA  . MET A 1 357 ? 106.072 111.698 124.777 1.00 54.12  ? 357 MET B CA  1 
ATOM   2252 C  C   . MET A 1 357 ? 106.458 110.276 124.395 1.00 54.12  ? 357 MET B C   1 
ATOM   2253 O  O   . MET A 1 357 ? 106.982 110.054 123.299 1.00 54.12  ? 357 MET B O   1 
ATOM   2254 C  CB  . MET A 1 357 ? 107.266 112.402 125.414 1.00 54.12  ? 357 MET B CB  1 
ATOM   2255 C  CG  . MET A 1 357 ? 107.501 113.808 124.909 1.00 54.12  ? 357 MET B CG  1 
ATOM   2256 S  SD  . MET A 1 357 ? 108.932 114.553 125.703 1.00 54.12  ? 357 MET B SD  1 
ATOM   2257 C  CE  . MET A 1 357 ? 108.504 116.281 125.602 1.00 54.12  ? 357 MET B CE  1 
ATOM   2258 N  N   . ALA A 1 358 ? 106.238 109.308 125.287 1.00 56.16  ? 358 ALA B N   1 
ATOM   2259 C  CA  . ALA A 1 358 ? 106.517 107.917 124.949 1.00 56.16  ? 358 ALA B CA  1 
ATOM   2260 C  C   . ALA A 1 358 ? 105.661 107.470 123.773 1.00 56.16  ? 358 ALA B C   1 
ATOM   2261 O  O   . ALA A 1 358 ? 106.160 106.870 122.815 1.00 56.16  ? 358 ALA B O   1 
ATOM   2262 C  CB  . ALA A 1 358 ? 106.283 107.022 126.165 1.00 56.16  ? 358 ALA B CB  1 
ATOM   2263 N  N   . LEU A 1 359 ? 104.366 107.765 123.824 1.00 54.51  ? 359 LEU B N   1 
ATOM   2264 C  CA  . LEU A 1 359 ? 103.538 107.648 122.640 1.00 54.51  ? 359 LEU B CA  1 
ATOM   2265 C  C   . LEU A 1 359 ? 103.870 108.784 121.677 1.00 54.51  ? 359 LEU B C   1 
ATOM   2266 O  O   . LEU A 1 359 ? 104.612 109.712 122.006 1.00 54.51  ? 359 LEU B O   1 
ATOM   2267 C  CB  . LEU A 1 359 ? 102.056 107.673 123.011 1.00 54.51  ? 359 LEU B CB  1 
ATOM   2268 C  CG  . LEU A 1 359 ? 101.633 106.826 124.211 1.00 54.51  ? 359 LEU B CG  1 
ATOM   2269 C  CD1 . LEU A 1 359 ? 100.137 106.941 124.439 1.00 54.51  ? 359 LEU B CD1 1 
ATOM   2270 C  CD2 . LEU A 1 359 ? 102.034 105.375 124.012 1.00 54.51  ? 359 LEU B CD2 1 
ATOM   2271 N  N   . LEU A 1 360 ? 103.358 108.670 120.453 1.00 60.92  ? 360 LEU B N   1 
ATOM   2272 C  CA  . LEU A 1 360 ? 103.498 109.707 119.434 1.00 60.92  ? 360 LEU B CA  1 
ATOM   2273 C  C   . LEU A 1 360 ? 104.936 109.794 118.932 1.00 60.92  ? 360 LEU B C   1 
ATOM   2274 O  O   . LEU A 1 360 ? 105.222 110.522 117.976 1.00 60.92  ? 360 LEU B O   1 
ATOM   2275 C  CB  . LEU A 1 360 ? 103.026 111.063 119.969 1.00 60.92  ? 360 LEU B CB  1 
ATOM   2276 C  CG  . LEU A 1 360 ? 101.542 111.207 120.303 1.00 60.92  ? 360 LEU B CG  1 
ATOM   2277 C  CD1 . LEU A 1 360 ? 101.275 112.555 120.948 1.00 60.92  ? 360 LEU B CD1 1 
ATOM   2278 C  CD2 . LEU A 1 360 ? 100.690 111.030 119.058 1.00 60.92  ? 360 LEU B CD2 1 
ATOM   2279 N  N   . TRP A 1 361 ? 105.847 109.062 119.572 1.00 61.33  ? 361 TRP B N   1 
ATOM   2280 C  CA  . TRP A 1 361 ? 107.157 108.753 119.014 1.00 61.33  ? 361 TRP B CA  1 
ATOM   2281 C  C   . TRP A 1 361 ? 107.178 107.349 118.432 1.00 61.33  ? 361 TRP B C   1 
ATOM   2282 O  O   . TRP A 1 361 ? 107.529 107.160 117.264 1.00 61.33  ? 361 TRP B O   1 
ATOM   2283 C  CB  . TRP A 1 361 ? 108.251 108.898 120.078 1.00 61.33  ? 361 TRP B CB  1 
ATOM   2284 C  CG  . TRP A 1 361 ? 108.848 110.268 120.150 1.00 61.33  ? 361 TRP B CG  1 
ATOM   2285 C  CD1 . TRP A 1 361 ? 108.842 111.215 119.173 1.00 61.33  ? 361 TRP B CD1 1 
ATOM   2286 C  CD2 . TRP A 1 361 ? 109.560 110.837 121.255 1.00 61.33  ? 361 TRP B CD2 1 
ATOM   2287 N  NE1 . TRP A 1 361 ? 109.495 112.344 119.602 1.00 61.33  ? 361 TRP B NE1 1 
ATOM   2288 C  CE2 . TRP A 1 361 ? 109.946 112.136 120.878 1.00 61.33  ? 361 TRP B CE2 1 
ATOM   2289 C  CE3 . TRP A 1 361 ? 109.905 110.375 122.528 1.00 61.33  ? 361 TRP B CE3 1 
ATOM   2290 C  CZ2 . TRP A 1 361 ? 110.656 112.978 121.728 1.00 61.33  ? 361 TRP B CZ2 1 
ATOM   2291 C  CZ3 . TRP A 1 361 ? 110.610 111.213 123.369 1.00 61.33  ? 361 TRP B CZ3 1 
ATOM   2292 C  CH2 . TRP A 1 361 ? 110.978 112.498 122.966 1.00 61.33  ? 361 TRP B CH2 1 
ATOM   2293 N  N   . PHE A 1 362 ? 106.803 106.357 119.233 1.00 69.79  ? 362 PHE B N   1 
ATOM   2294 C  CA  . PHE A 1 362 ? 106.371 105.085 118.689 1.00 69.79  ? 362 PHE B CA  1 
ATOM   2295 C  C   . PHE A 1 362 ? 104.944 105.228 118.166 1.00 69.79  ? 362 PHE B C   1 
ATOM   2296 O  O   . PHE A 1 362 ? 104.252 106.213 118.437 1.00 69.79  ? 362 PHE B O   1 
ATOM   2297 C  CB  . PHE A 1 362 ? 106.457 103.982 119.744 1.00 69.79  ? 362 PHE B CB  1 
ATOM   2298 C  CG  . PHE A 1 362 ? 107.654 104.095 120.646 1.00 69.79  ? 362 PHE B CG  1 
ATOM   2299 C  CD1 . PHE A 1 362 ? 108.935 104.120 120.121 1.00 69.79  ? 362 PHE B CD1 1 
ATOM   2300 C  CD2 . PHE A 1 362 ? 107.498 104.166 122.019 1.00 69.79  ? 362 PHE B CD2 1 
ATOM   2301 C  CE1 . PHE A 1 362 ? 110.036 104.225 120.950 1.00 69.79  ? 362 PHE B CE1 1 
ATOM   2302 C  CE2 . PHE A 1 362 ? 108.594 104.269 122.852 1.00 69.79  ? 362 PHE B CE2 1 
ATOM   2303 C  CZ  . PHE A 1 362 ? 109.865 104.299 122.317 1.00 69.79  ? 362 PHE B CZ  1 
ATOM   2304 N  N   . SER A 1 363 ? 104.510 104.237 117.389 1.00 88.41  ? 363 SER B N   1 
ATOM   2305 C  CA  . SER A 1 363 ? 103.224 104.208 116.698 1.00 88.41  ? 363 SER B CA  1 
ATOM   2306 C  C   . SER A 1 363 ? 103.116 105.279 115.619 1.00 88.41  ? 363 SER B C   1 
ATOM   2307 O  O   . SER A 1 363 ? 102.064 105.384 114.976 1.00 88.41  ? 363 SER B O   1 
ATOM   2308 C  CB  . SER A 1 363 ? 102.032 104.347 117.657 1.00 88.41  ? 363 SER B CB  1 
ATOM   2309 O  OG  . SER A 1 363 ? 101.924 105.674 118.141 1.00 88.41  ? 363 SER B OG  1 
ATOM   2310 N  N   . ARG A 1 364 ? 104.158 106.080 115.397 1.00 89.30  ? 364 ARG B N   1 
ATOM   2311 C  CA  . ARG A 1 364 ? 104.148 107.036 114.291 1.00 89.30  ? 364 ARG B CA  1 
ATOM   2312 C  C   . ARG A 1 364 ? 104.536 106.345 112.988 1.00 89.30  ? 364 ARG B C   1 
ATOM   2313 O  O   . ARG A 1 364 ? 103.737 106.263 112.050 1.00 89.30  ? 364 ARG B O   1 
ATOM   2314 C  CB  . ARG A 1 364 ? 105.095 108.202 114.595 1.00 89.30  ? 364 ARG B CB  1 
ATOM   2315 C  CG  . ARG A 1 364 ? 104.683 109.516 113.964 1.00 89.30  ? 364 ARG B CG  1 
ATOM   2316 C  CD  . ARG A 1 364 ? 105.603 110.643 114.400 1.00 89.30  ? 364 ARG B CD  1 
ATOM   2317 N  NE  . ARG A 1 364 ? 106.994 110.393 114.037 1.00 89.30  ? 364 ARG B NE  1 
ATOM   2318 C  CZ  . ARG A 1 364 ? 107.459 110.369 112.796 1.00 89.30  ? 364 ARG B CZ  1 
ATOM   2319 N  NH1 . ARG A 1 364 ? 106.675 110.601 111.756 1.00 89.30  ? 364 ARG B NH1 1 
ATOM   2320 N  NH2 . ARG A 1 364 ? 108.748 110.112 112.592 1.00 89.30  ? 364 ARG B NH2 1 
ATOM   2321 N  N   . ASP A 1 365 ? 105.764 105.835 112.922 1.00 99.19  ? 365 ASP B N   1 
ATOM   2322 C  CA  . ASP A 1 365 ? 106.243 105.052 111.781 1.00 99.19  ? 365 ASP B CA  1 
ATOM   2323 C  C   . ASP A 1 365 ? 106.978 103.825 112.300 1.00 99.19  ? 365 ASP B C   1 
ATOM   2324 O  O   . ASP A 1 365 ? 108.204 103.715 112.176 1.00 99.19  ? 365 ASP B O   1 
ATOM   2325 C  CB  . ASP A 1 365 ? 107.146 105.895 110.880 1.00 99.19  ? 365 ASP B CB  1 
ATOM   2326 C  CG  . ASP A 1 365 ? 106.423 107.074 110.268 1.00 99.19  ? 365 ASP B CG  1 
ATOM   2327 O  OD1 . ASP A 1 365 ? 105.295 106.886 109.766 1.00 99.19  ? 365 ASP B OD1 1 
ATOM   2328 O  OD2 . ASP A 1 365 ? 106.983 108.190 110.290 1.00 99.19  ? 365 ASP B OD2 1 
ATOM   2329 N  N   . PRO A 1 366 ? 106.258 102.880 112.901 1.00 106.10 ? 366 PRO B N   1 
ATOM   2330 C  CA  . PRO A 1 366 ? 106.919 101.677 113.415 1.00 106.10 ? 366 PRO B CA  1 
ATOM   2331 C  C   . PRO A 1 366 ? 107.468 100.823 112.284 1.00 106.10 ? 366 PRO B C   1 
ATOM   2332 O  O   . PRO A 1 366 ? 106.918 100.777 111.181 1.00 106.10 ? 366 PRO B O   1 
ATOM   2333 C  CB  . PRO A 1 366 ? 105.803 100.947 114.175 1.00 106.10 ? 366 PRO B CB  1 
ATOM   2334 C  CG  . PRO A 1 366 ? 104.669 101.929 114.277 1.00 106.10 ? 366 PRO B CG  1 
ATOM   2335 C  CD  . PRO A 1 366 ? 104.802 102.830 113.100 1.00 106.10 ? 366 PRO B CD  1 
ATOM   2336 N  N   . GLY A 1 367 ? 108.579 100.144 112.574 1.00 111.54 ? 367 GLY B N   1 
ATOM   2337 C  CA  . GLY A 1 367 ? 109.218 99.325  111.556 1.00 111.54 ? 367 GLY B CA  1 
ATOM   2338 C  C   . GLY A 1 367 ? 108.376 98.132  111.143 1.00 111.54 ? 367 GLY B C   1 
ATOM   2339 O  O   . GLY A 1 367 ? 108.241 97.835  109.953 1.00 111.54 ? 367 GLY B O   1 
ATOM   2340 N  N   . PHE A 1 368 ? 107.798 97.431  112.119 1.00 119.14 ? 368 PHE B N   1 
ATOM   2341 C  CA  . PHE A 1 368 ? 107.057 96.201  111.855 1.00 119.14 ? 368 PHE B CA  1 
ATOM   2342 C  C   . PHE A 1 368 ? 105.557 96.441  111.717 1.00 119.14 ? 368 PHE B C   1 
ATOM   2343 O  O   . PHE A 1 368 ? 104.974 96.166  110.664 1.00 119.14 ? 368 PHE B O   1 
ATOM   2344 C  CB  . PHE A 1 368 ? 107.334 95.180  112.967 1.00 119.14 ? 368 PHE B CB  1 
ATOM   2345 N  N   . VAL A 1 369 ? 104.922 96.952  112.762 1.00 119.54 ? 369 VAL B N   1 
ATOM   2346 C  CA  . VAL A 1 369 ? 103.468 97.128  112.757 1.00 119.54 ? 369 VAL B CA  1 
ATOM   2347 C  C   . VAL A 1 369 ? 103.130 98.437  112.049 1.00 119.54 ? 369 VAL B C   1 
ATOM   2348 O  O   . VAL A 1 369 ? 103.682 99.486  112.412 1.00 119.54 ? 369 VAL B O   1 
ATOM   2349 C  CB  . VAL A 1 369 ? 102.922 97.117  114.181 1.00 119.54 ? 369 VAL B CB  1 
ATOM   2350 C  CG1 . VAL A 1 369 ? 101.401 97.198  114.168 1.00 119.54 ? 369 VAL B CG1 1 
ATOM   2351 C  CG2 . VAL A 1 369 ? 103.387 95.868  114.916 1.00 119.54 ? 369 VAL B CG2 1 
ATOM   2352 N  N   . PRO A 1 370 ? 102.248 98.424  111.049 1.00 119.43 ? 370 PRO B N   1 
ATOM   2353 C  CA  . PRO A 1 370 ? 101.866 99.678  110.382 1.00 119.43 ? 370 PRO B CA  1 
ATOM   2354 C  C   . PRO A 1 370 ? 101.078 100.573 111.327 1.00 119.43 ? 370 PRO B C   1 
ATOM   2355 O  O   . PRO A 1 370 ? 99.983  100.220 111.770 1.00 119.43 ? 370 PRO B O   1 
ATOM   2356 C  CB  . PRO A 1 370 ? 101.013 99.203  109.200 1.00 119.43 ? 370 PRO B CB  1 
ATOM   2357 C  CG  . PRO A 1 370 ? 100.449 97.898  109.656 1.00 119.43 ? 370 PRO B CG  1 
ATOM   2358 C  CD  . PRO A 1 370 ? 101.515 97.264  110.512 1.00 119.43 ? 370 PRO B CD  1 
ATOM   2359 N  N   . GLY A 1 371 ? 101.643 101.737 111.635 1.00 117.77 ? 371 GLY B N   1 
ATOM   2360 C  CA  . GLY A 1 371 ? 100.998 102.675 112.531 1.00 117.77 ? 371 GLY B CA  1 
ATOM   2361 C  C   . GLY A 1 371 ? 100.367 103.845 111.806 1.00 117.77 ? 371 GLY B C   1 
ATOM   2362 O  O   . GLY A 1 371 ? 101.071 104.731 111.312 1.00 117.77 ? 371 GLY B O   1 
ATOM   2363 N  N   . TRP A 1 372 ? 99.036  103.859 111.739 1.00 121.07 ? 372 TRP B N   1 
ATOM   2364 C  CA  . TRP A 1 372 ? 98.301  104.905 111.038 1.00 121.07 ? 372 TRP B CA  1 
ATOM   2365 C  C   . TRP A 1 372 ? 97.618  105.880 111.989 1.00 121.07 ? 372 TRP B C   1 
ATOM   2366 O  O   . TRP A 1 372 ? 96.922  106.792 111.526 1.00 121.07 ? 372 TRP B O   1 
ATOM   2367 C  CB  . TRP A 1 372 ? 97.266  104.285 110.094 1.00 121.07 ? 372 TRP B CB  1 
ATOM   2368 N  N   . SER A 1 373 ? 97.787  105.709 113.302 1.00 119.51 ? 373 SER B N   1 
ATOM   2369 C  CA  . SER A 1 373 ? 97.225  106.668 114.247 1.00 119.51 ? 373 SER B CA  1 
ATOM   2370 C  C   . SER A 1 373 ? 97.874  108.037 114.086 1.00 119.51 ? 373 SER B C   1 
ATOM   2371 O  O   . SER A 1 373 ? 97.193  109.068 114.137 1.00 119.51 ? 373 SER B O   1 
ATOM   2372 C  CB  . SER A 1 373 ? 97.390  106.155 115.678 1.00 119.51 ? 373 SER B CB  1 
ATOM   2373 O  OG  . SER A 1 373 ? 96.655  106.949 116.593 1.00 119.51 ? 373 SER B OG  1 
ATOM   2374 N  N   . ALA A 1 374 ? 99.187  108.066 113.892 1.00 109.31 ? 374 ALA B N   1 
ATOM   2375 C  CA  . ALA A 1 374 ? 99.923  109.288 113.616 1.00 109.31 ? 374 ALA B CA  1 
ATOM   2376 C  C   . ALA A 1 374 ? 100.439 109.262 112.183 1.00 109.31 ? 374 ALA B C   1 
ATOM   2377 O  O   . ALA A 1 374 ? 100.523 108.207 111.549 1.00 109.31 ? 374 ALA B O   1 
ATOM   2378 C  CB  . ALA A 1 374 ? 101.085 109.467 114.600 1.00 109.31 ? 374 ALA B CB  1 
ATOM   2379 N  N   . LEU A 1 375 ? 100.776 110.450 111.677 1.00 106.56 ? 375 LEU B N   1 
ATOM   2380 C  CA  . LEU A 1 375 ? 101.196 110.636 110.288 1.00 106.56 ? 375 LEU B CA  1 
ATOM   2381 C  C   . LEU A 1 375 ? 100.126 110.160 109.307 1.00 106.56 ? 375 LEU B C   1 
ATOM   2382 O  O   . LEU A 1 375 ? 100.434 109.674 108.216 1.00 106.56 ? 375 LEU B O   1 
ATOM   2383 C  CB  . LEU A 1 375 ? 102.536 109.948 110.005 1.00 106.56 ? 375 LEU B CB  1 
ATOM   2384 C  CG  . LEU A 1 375 ? 103.357 110.542 108.855 1.00 106.56 ? 375 LEU B CG  1 
ATOM   2385 C  CD1 . LEU A 1 375 ? 103.436 112.057 108.962 1.00 106.56 ? 375 LEU B CD1 1 
ATOM   2386 C  CD2 . LEU A 1 375 ? 104.747 109.935 108.807 1.00 106.56 ? 375 LEU B CD2 1 
ATOM   2387 N  N   . PHE A 1 376 ? 98.859  110.285 109.694 1.00 111.15 ? 376 PHE B N   1 
ATOM   2388 C  CA  . PHE A 1 376 ? 97.750  110.054 108.782 1.00 111.15 ? 376 PHE B CA  1 
ATOM   2389 C  C   . PHE A 1 376 ? 97.272  111.331 108.106 1.00 111.15 ? 376 PHE B C   1 
ATOM   2390 O  O   . PHE A 1 376 ? 96.413  111.263 107.221 1.00 111.15 ? 376 PHE B O   1 
ATOM   2391 C  CB  . PHE A 1 376 ? 96.579  109.400 109.525 1.00 111.15 ? 376 PHE B CB  1 
ATOM   2392 C  CG  . PHE A 1 376 ? 95.698  110.377 110.249 1.00 111.15 ? 376 PHE B CG  1 
ATOM   2393 C  CD1 . PHE A 1 376 ? 96.106  110.942 111.445 1.00 111.15 ? 376 PHE B CD1 1 
ATOM   2394 C  CD2 . PHE A 1 376 ? 94.461  110.730 109.735 1.00 111.15 ? 376 PHE B CD2 1 
ATOM   2395 C  CE1 . PHE A 1 376 ? 95.299  111.841 112.115 1.00 111.15 ? 376 PHE B CE1 1 
ATOM   2396 C  CE2 . PHE A 1 376 ? 93.649  111.629 110.400 1.00 111.15 ? 376 PHE B CE2 1 
ATOM   2397 C  CZ  . PHE A 1 376 ? 94.069  112.185 111.591 1.00 111.15 ? 376 PHE B CZ  1 
ATOM   2398 N  N   . SER A 1 377 ? 97.806  112.484 108.500 1.00 110.26 ? 377 SER B N   1 
ATOM   2399 C  CA  . SER A 1 377 ? 97.372  113.750 107.930 1.00 110.26 ? 377 SER B CA  1 
ATOM   2400 C  C   . SER A 1 377 ? 98.036  113.989 106.580 1.00 110.26 ? 377 SER B C   1 
ATOM   2401 O  O   . SER A 1 377 ? 99.225  113.718 106.395 1.00 110.26 ? 377 SER B O   1 
ATOM   2402 C  CB  . SER A 1 377 ? 97.697  114.898 108.884 1.00 110.26 ? 377 SER B CB  1 
ATOM   2403 O  OG  . SER A 1 377 ? 97.131  114.673 110.164 1.00 110.26 ? 377 SER B OG  1 
ATOM   2404 N  N   . GLU A 1 378 ? 97.252  114.504 105.629 1.00 111.34 ? 378 GLU B N   1 
ATOM   2405 C  CA  . GLU A 1 378 ? 97.794  114.848 104.321 1.00 111.34 ? 378 GLU B CA  1 
ATOM   2406 C  C   . GLU A 1 378 ? 98.660  116.100 104.368 1.00 111.34 ? 378 GLU B C   1 
ATOM   2407 O  O   . GLU A 1 378 ? 99.439  116.333 103.438 1.00 111.34 ? 378 GLU B O   1 
ATOM   2408 C  CB  . GLU A 1 378 ? 96.659  115.032 103.312 1.00 111.34 ? 378 GLU B CB  1 
ATOM   2409 C  CG  . GLU A 1 378 ? 95.579  116.012 103.748 1.00 111.34 ? 378 GLU B CG  1 
ATOM   2410 C  CD  . GLU A 1 378 ? 95.904  117.447 103.379 1.00 111.34 ? 378 GLU B CD  1 
ATOM   2411 O  OE1 . GLU A 1 378 ? 96.744  117.656 102.479 1.00 111.34 ? 378 GLU B OE1 1 
ATOM   2412 O  OE2 . GLU A 1 378 ? 95.317  118.367 103.987 1.00 111.34 ? 378 GLU B OE2 1 
ATOM   2413 N  N   . TYR A 1 379 ? 98.533  116.906 105.414 1.00 108.25 ? 379 TYR B N   1 
ATOM   2414 C  CA  . TYR A 1 379 ? 99.374  118.088 105.553 1.00 108.25 ? 379 TYR B CA  1 
ATOM   2415 C  C   . TYR A 1 379 ? 100.822 117.665 105.771 1.00 108.25 ? 379 TYR B C   1 
ATOM   2416 O  O   . TYR A 1 379 ? 101.086 116.772 106.584 1.00 108.25 ? 379 TYR B O   1 
ATOM   2417 C  CB  . TYR A 1 379 ? 98.902  118.961 106.717 1.00 108.25 ? 379 TYR B CB  1 
ATOM   2418 C  CG  . TYR A 1 379 ? 97.409  119.208 106.762 1.00 108.25 ? 379 TYR B CG  1 
ATOM   2419 C  CD1 . TYR A 1 379 ? 96.870  120.395 106.283 1.00 108.25 ? 379 TYR B CD1 1 
ATOM   2420 C  CD2 . TYR A 1 379 ? 96.541  118.268 107.305 1.00 108.25 ? 379 TYR B CD2 1 
ATOM   2421 C  CE1 . TYR A 1 379 ? 95.509  120.632 106.326 1.00 108.25 ? 379 TYR B CE1 1 
ATOM   2422 C  CE2 . TYR A 1 379 ? 95.179  118.496 107.352 1.00 108.25 ? 379 TYR B CE2 1 
ATOM   2423 C  CZ  . TYR A 1 379 ? 94.669  119.679 106.862 1.00 108.25 ? 379 TYR B CZ  1 
ATOM   2424 O  OH  . TYR A 1 379 ? 93.313  119.911 106.908 1.00 108.25 ? 379 TYR B OH  1 
ATOM   2425 N  N   . PRO A 1 380 ? 101.780 118.270 105.076 1.00 102.15 ? 380 PRO B N   1 
ATOM   2426 C  CA  . PRO A 1 380 ? 103.180 117.885 105.263 1.00 102.15 ? 380 PRO B CA  1 
ATOM   2427 C  C   . PRO A 1 380 ? 103.794 118.570 106.472 1.00 102.15 ? 380 PRO B C   1 
ATOM   2428 O  O   . PRO A 1 380 ? 103.568 119.753 106.736 1.00 102.15 ? 380 PRO B O   1 
ATOM   2429 C  CB  . PRO A 1 380 ? 103.849 118.349 103.964 1.00 102.15 ? 380 PRO B CB  1 
ATOM   2430 C  CG  . PRO A 1 380 ? 102.970 119.456 103.442 1.00 102.15 ? 380 PRO B CG  1 
ATOM   2431 C  CD  . PRO A 1 380 ? 101.629 119.390 104.133 1.00 102.15 ? 380 PRO B CD  1 
ATOM   2432 N  N   . GLY A 1 381 ? 104.580 117.795 107.217 1.00 94.39  ? 381 GLY B N   1 
ATOM   2433 C  CA  . GLY A 1 381 ? 105.223 118.286 108.415 1.00 94.39  ? 381 GLY B CA  1 
ATOM   2434 C  C   . GLY A 1 381 ? 104.339 118.339 109.639 1.00 94.39  ? 381 GLY B C   1 
ATOM   2435 O  O   . GLY A 1 381 ? 104.814 118.745 110.707 1.00 94.39  ? 381 GLY B O   1 
ATOM   2436 N  N   . PHE A 1 382 ? 103.069 117.945 109.523 1.00 96.60  ? 382 PHE B N   1 
ATOM   2437 C  CA  . PHE A 1 382 ? 102.176 117.958 110.677 1.00 96.60  ? 382 PHE B CA  1 
ATOM   2438 C  C   . PHE A 1 382 ? 102.652 117.001 111.761 1.00 96.60  ? 382 PHE B C   1 
ATOM   2439 O  O   . PHE A 1 382 ? 102.626 117.337 112.950 1.00 96.60  ? 382 PHE B O   1 
ATOM   2440 C  CB  . PHE A 1 382 ? 100.755 117.608 110.239 1.00 96.60  ? 382 PHE B CB  1 
ATOM   2441 C  CG  . PHE A 1 382 ? 99.768  117.547 111.369 1.00 96.60  ? 382 PHE B CG  1 
ATOM   2442 C  CD1 . PHE A 1 382 ? 99.304  118.706 111.965 1.00 96.60  ? 382 PHE B CD1 1 
ATOM   2443 C  CD2 . PHE A 1 382 ? 99.296  116.327 111.826 1.00 96.60  ? 382 PHE B CD2 1 
ATOM   2444 C  CE1 . PHE A 1 382 ? 98.393  118.651 113.004 1.00 96.60  ? 382 PHE B CE1 1 
ATOM   2445 C  CE2 . PHE A 1 382 ? 98.385  116.265 112.863 1.00 96.60  ? 382 PHE B CE2 1 
ATOM   2446 C  CZ  . PHE A 1 382 ? 97.933  117.428 113.453 1.00 96.60  ? 382 PHE B CZ  1 
ATOM   2447 N  N   . ALA A 1 383 ? 103.090 115.807 111.371 1.00 91.59  ? 383 ALA B N   1 
ATOM   2448 C  CA  . ALA A 1 383 ? 103.536 114.780 112.309 1.00 91.59  ? 383 ALA B CA  1 
ATOM   2449 C  C   . ALA A 1 383 ? 104.987 114.435 111.992 1.00 91.59  ? 383 ALA B C   1 
ATOM   2450 O  O   . ALA A 1 383 ? 105.272 113.762 110.997 1.00 91.59  ? 383 ALA B O   1 
ATOM   2451 C  CB  . ALA A 1 383 ? 102.642 113.546 112.239 1.00 91.59  ? 383 ALA B CB  1 
ATOM   2452 N  N   . THR A 1 384 ? 105.900 114.900 112.840 1.00 79.48  ? 384 THR B N   1 
ATOM   2453 C  CA  . THR A 1 384 ? 107.310 114.566 112.721 1.00 79.48  ? 384 THR B CA  1 
ATOM   2454 C  C   . THR A 1 384 ? 107.908 114.530 114.118 1.00 79.48  ? 384 THR B C   1 
ATOM   2455 O  O   . THR A 1 384 ? 107.317 115.031 115.078 1.00 79.48  ? 384 THR B O   1 
ATOM   2456 C  CB  . THR A 1 384 ? 108.063 115.558 111.827 1.00 79.48  ? 384 THR B CB  1 
ATOM   2457 O  OG1 . THR A 1 384 ? 109.410 115.107 111.637 1.00 79.48  ? 384 THR B OG1 1 
ATOM   2458 C  CG2 . THR A 1 384 ? 108.081 116.937 112.454 1.00 79.48  ? 384 THR B CG2 1 
ATOM   2459 N  N   . ASP A 1 385 ? 109.089 113.917 114.224 1.00 74.22  ? 385 ASP B N   1 
ATOM   2460 C  CA  . ASP A 1 385 ? 109.702 113.718 115.534 1.00 74.22  ? 385 ASP B CA  1 
ATOM   2461 C  C   . ASP A 1 385 ? 110.017 115.043 116.216 1.00 74.22  ? 385 ASP B C   1 
ATOM   2462 O  O   . ASP A 1 385 ? 109.790 115.194 117.421 1.00 74.22  ? 385 ASP B O   1 
ATOM   2463 C  CB  . ASP A 1 385 ? 110.965 112.871 115.397 1.00 74.22  ? 385 ASP B CB  1 
ATOM   2464 C  CG  . ASP A 1 385 ? 110.663 111.439 115.012 1.00 74.22  ? 385 ASP B CG  1 
ATOM   2465 O  OD1 . ASP A 1 385 ? 109.575 110.942 115.371 1.00 74.22  ? 385 ASP B OD1 1 
ATOM   2466 O  OD2 . ASP A 1 385 ? 111.513 110.810 114.349 1.00 74.22  ? 385 ASP B OD2 1 
ATOM   2467 N  N   . SER A 1 386 ? 110.542 116.015 115.466 1.00 70.94  ? 386 SER B N   1 
ATOM   2468 C  CA  . SER A 1 386 ? 110.905 117.296 116.066 1.00 70.94  ? 386 SER B CA  1 
ATOM   2469 C  C   . SER A 1 386 ? 109.680 118.035 116.590 1.00 70.94  ? 386 SER B C   1 
ATOM   2470 O  O   . SER A 1 386 ? 109.711 118.608 117.688 1.00 70.94  ? 386 SER B O   1 
ATOM   2471 C  CB  . SER A 1 386 ? 111.644 118.156 115.045 1.00 70.94  ? 386 SER B CB  1 
ATOM   2472 O  OG  . SER A 1 386 ? 110.772 118.573 114.010 1.00 70.94  ? 386 SER B OG  1 
ATOM   2473 N  N   . THR A 1 387 ? 108.597 118.048 115.812 1.00 68.49  ? 387 THR B N   1 
ATOM   2474 C  CA  . THR A 1 387 ? 107.384 118.736 116.240 1.00 68.49  ? 387 THR B CA  1 
ATOM   2475 C  C   . THR A 1 387 ? 106.789 118.083 117.479 1.00 68.49  ? 387 THR B C   1 
ATOM   2476 O  O   . THR A 1 387 ? 106.529 118.755 118.482 1.00 68.49  ? 387 THR B O   1 
ATOM   2477 C  CB  . THR A 1 387 ? 106.360 118.755 115.108 1.00 68.49  ? 387 THR B CB  1 
ATOM   2478 O  OG1 . THR A 1 387 ? 106.856 119.549 114.023 1.00 68.49  ? 387 THR B OG1 1 
ATOM   2479 C  CG2 . THR A 1 387 ? 105.047 119.331 115.596 1.00 68.49  ? 387 THR B CG2 1 
ATOM   2480 N  N   . VAL A 1 388 ? 106.568 116.768 117.433 1.00 63.35  ? 388 VAL B N   1 
ATOM   2481 C  CA  . VAL A 1 388 ? 105.991 116.084 118.582 1.00 63.35  ? 388 VAL B CA  1 
ATOM   2482 C  C   . VAL A 1 388 ? 106.932 116.122 119.776 1.00 63.35  ? 388 VAL B C   1 
ATOM   2483 O  O   . VAL A 1 388 ? 106.490 115.962 120.920 1.00 63.35  ? 388 VAL B O   1 
ATOM   2484 C  CB  . VAL A 1 388 ? 105.615 114.636 118.218 1.00 63.35  ? 388 VAL B CB  1 
ATOM   2485 C  CG1 . VAL A 1 388 ? 106.860 113.792 118.029 1.00 63.35  ? 388 VAL B CG1 1 
ATOM   2486 C  CG2 . VAL A 1 388 ? 104.710 114.041 119.276 1.00 63.35  ? 388 VAL B CG2 1 
ATOM   2487 N  N   . ALA A 1 389 ? 108.225 116.346 119.544 1.00 61.55  ? 389 ALA B N   1 
ATOM   2488 C  CA  . ALA A 1 389 ? 109.161 116.487 120.650 1.00 61.55  ? 389 ALA B CA  1 
ATOM   2489 C  C   . ALA A 1 389 ? 109.005 117.843 121.322 1.00 61.55  ? 389 ALA B C   1 
ATOM   2490 O  O   . ALA A 1 389 ? 108.636 117.928 122.497 1.00 61.55  ? 389 ALA B O   1 
ATOM   2491 C  CB  . ALA A 1 389 ? 110.593 116.288 120.154 1.00 61.55  ? 389 ALA B CB  1 
ATOM   2492 N  N   . LEU A 1 390 ? 109.256 118.925 120.582 1.00 57.37  ? 390 LEU B N   1 
ATOM   2493 C  CA  . LEU A 1 390 ? 109.287 120.232 121.233 1.00 57.37  ? 390 LEU B CA  1 
ATOM   2494 C  C   . LEU A 1 390 ? 107.907 120.780 121.568 1.00 57.37  ? 390 LEU B C   1 
ATOM   2495 O  O   . LEU A 1 390 ? 107.778 121.501 122.560 1.00 57.37  ? 390 LEU B O   1 
ATOM   2496 C  CB  . LEU A 1 390 ? 110.048 121.259 120.402 1.00 57.37  ? 390 LEU B CB  1 
ATOM   2497 C  CG  . LEU A 1 390 ? 111.550 121.029 120.304 1.00 57.37  ? 390 LEU B CG  1 
ATOM   2498 C  CD1 . LEU A 1 390 ? 112.123 121.834 119.170 1.00 57.37  ? 390 LEU B CD1 1 
ATOM   2499 C  CD2 . LEU A 1 390 ? 112.209 121.391 121.613 1.00 57.37  ? 390 LEU B CD2 1 
ATOM   2500 N  N   . LEU A 1 391 ? 106.873 120.474 120.781 1.00 52.53  ? 391 LEU B N   1 
ATOM   2501 C  CA  . LEU A 1 391 ? 105.542 120.971 121.109 1.00 52.53  ? 391 LEU B CA  1 
ATOM   2502 C  C   . LEU A 1 391 ? 105.108 120.515 122.496 1.00 52.53  ? 391 LEU B C   1 
ATOM   2503 O  O   . LEU A 1 391 ? 104.285 121.177 123.138 1.00 52.53  ? 391 LEU B O   1 
ATOM   2504 C  CB  . LEU A 1 391 ? 104.546 120.508 120.045 1.00 52.53  ? 391 LEU B CB  1 
ATOM   2505 C  CG  . LEU A 1 391 ? 103.048 120.684 120.293 1.00 52.53  ? 391 LEU B CG  1 
ATOM   2506 C  CD1 . LEU A 1 391 ? 102.704 122.151 120.481 1.00 52.53  ? 391 LEU B CD1 1 
ATOM   2507 C  CD2 . LEU A 1 391 ? 102.245 120.081 119.152 1.00 52.53  ? 391 LEU B CD2 1 
ATOM   2508 N  N   . ILE A 1 392 ? 105.663 119.405 122.980 1.00 51.19  ? 392 ILE B N   1 
ATOM   2509 C  CA  . ILE A 1 392 ? 105.374 118.906 124.319 1.00 51.19  ? 392 ILE B CA  1 
ATOM   2510 C  C   . ILE A 1 392 ? 106.473 119.351 125.279 1.00 51.19  ? 392 ILE B C   1 
ATOM   2511 O  O   . ILE A 1 392 ? 106.206 119.640 126.450 1.00 51.19  ? 392 ILE B O   1 
ATOM   2512 C  CB  . ILE A 1 392 ? 105.226 117.374 124.317 1.00 51.19  ? 392 ILE B CB  1 
ATOM   2513 C  CG1 . ILE A 1 392 ? 104.167 116.941 123.303 1.00 51.19  ? 392 ILE B CG1 1 
ATOM   2514 C  CG2 . ILE A 1 392 ? 104.847 116.872 125.697 1.00 51.19  ? 392 ILE B CG2 1 
ATOM   2515 C  CD1 . ILE A 1 392 ? 102.786 117.472 123.597 1.00 51.19  ? 392 ILE B CD1 1 
ATOM   2516 N  N   . GLY A 1 393 ? 107.714 119.415 124.791 1.00 50.71  ? 393 GLY B N   1 
ATOM   2517 C  CA  . GLY A 1 393 ? 108.824 119.770 125.661 1.00 50.71  ? 393 GLY B CA  1 
ATOM   2518 C  C   . GLY A 1 393 ? 108.761 121.197 126.166 1.00 50.71  ? 393 GLY B C   1 
ATOM   2519 O  O   . GLY A 1 393 ? 109.023 121.458 127.342 1.00 50.71  ? 393 GLY B O   1 
ATOM   2520 N  N   . LEU A 1 394 ? 108.420 122.142 125.288 1.00 50.73  ? 394 LEU B N   1 
ATOM   2521 C  CA  . LEU A 1 394 ? 108.331 123.539 125.692 1.00 50.73  ? 394 LEU B CA  1 
ATOM   2522 C  C   . LEU A 1 394 ? 107.217 123.779 126.698 1.00 50.73  ? 394 LEU B C   1 
ATOM   2523 O  O   . LEU A 1 394 ? 107.214 124.820 127.362 1.00 50.73  ? 394 LEU B O   1 
ATOM   2524 C  CB  . LEU A 1 394 ? 108.137 124.437 124.470 1.00 50.73  ? 394 LEU B CB  1 
ATOM   2525 C  CG  . LEU A 1 394 ? 109.396 124.969 123.777 1.00 50.73  ? 394 LEU B CG  1 
ATOM   2526 C  CD1 . LEU A 1 394 ? 110.471 123.906 123.635 1.00 50.73  ? 394 LEU B CD1 1 
ATOM   2527 C  CD2 . LEU A 1 394 ? 109.042 125.548 122.420 1.00 50.73  ? 394 LEU B CD2 1 
ATOM   2528 N  N   . LEU A 1 395 ? 106.272 122.845 126.825 1.00 47.56  ? 395 LEU B N   1 
ATOM   2529 C  CA  . LEU A 1 395 ? 105.292 122.933 127.898 1.00 47.56  ? 395 LEU B CA  1 
ATOM   2530 C  C   . LEU A 1 395 ? 105.948 122.838 129.267 1.00 47.56  ? 395 LEU B C   1 
ATOM   2531 O  O   . LEU A 1 395 ? 105.381 123.323 130.250 1.00 47.56  ? 395 LEU B O   1 
ATOM   2532 C  CB  . LEU A 1 395 ? 104.239 121.838 127.741 1.00 47.56  ? 395 LEU B CB  1 
ATOM   2533 C  CG  . LEU A 1 395 ? 102.895 122.275 127.160 1.00 47.56  ? 395 LEU B CG  1 
ATOM   2534 C  CD1 . LEU A 1 395 ? 103.082 122.868 125.777 1.00 47.56  ? 395 LEU B CD1 1 
ATOM   2535 C  CD2 . LEU A 1 395 ? 101.930 121.105 127.114 1.00 47.56  ? 395 LEU B CD2 1 
ATOM   2536 N  N   . PHE A 1 396 ? 107.131 122.227 129.352 1.00 47.18  ? 396 PHE B N   1 
ATOM   2537 C  CA  . PHE A 1 396 ? 107.889 122.218 130.595 1.00 47.18  ? 396 PHE B CA  1 
ATOM   2538 C  C   . PHE A 1 396 ? 108.400 123.596 130.977 1.00 47.18  ? 396 PHE B C   1 
ATOM   2539 O  O   . PHE A 1 396 ? 108.832 123.779 132.117 1.00 47.18  ? 396 PHE B O   1 
ATOM   2540 C  CB  . PHE A 1 396 ? 109.074 121.260 130.490 1.00 47.18  ? 396 PHE B CB  1 
ATOM   2541 C  CG  . PHE A 1 396 ? 108.694 119.811 130.543 1.00 47.18  ? 396 PHE B CG  1 
ATOM   2542 C  CD1 . PHE A 1 396 ? 108.078 119.284 131.661 1.00 47.18  ? 396 PHE B CD1 1 
ATOM   2543 C  CD2 . PHE A 1 396 ? 108.956 118.976 129.474 1.00 47.18  ? 396 PHE B CD2 1 
ATOM   2544 C  CE1 . PHE A 1 396 ? 107.733 117.951 131.710 1.00 47.18  ? 396 PHE B CE1 1 
ATOM   2545 C  CE2 . PHE A 1 396 ? 108.612 117.644 129.519 1.00 47.18  ? 396 PHE B CE2 1 
ATOM   2546 C  CZ  . PHE A 1 396 ? 107.999 117.132 130.637 1.00 47.18  ? 396 PHE B CZ  1 
ATOM   2547 N  N   . PHE A 1 397 ? 108.385 124.556 130.053 1.00 46.99  ? 397 PHE B N   1 
ATOM   2548 C  CA  . PHE A 1 397 ? 108.871 125.902 130.319 1.00 46.99  ? 397 PHE B CA  1 
ATOM   2549 C  C   . PHE A 1 397 ? 107.774 126.875 130.723 1.00 46.99  ? 397 PHE B C   1 
ATOM   2550 O  O   . PHE A 1 397 ? 108.080 128.034 131.017 1.00 46.99  ? 397 PHE B O   1 
ATOM   2551 C  CB  . PHE A 1 397 ? 109.595 126.456 129.087 1.00 46.99  ? 397 PHE B CB  1 
ATOM   2552 C  CG  . PHE A 1 397 ? 111.027 126.032 128.983 1.00 46.99  ? 397 PHE B CG  1 
ATOM   2553 C  CD1 . PHE A 1 397 ? 111.997 126.631 129.762 1.00 46.99  ? 397 PHE B CD1 1 
ATOM   2554 C  CD2 . PHE A 1 397 ? 111.406 125.042 128.098 1.00 46.99  ? 397 PHE B CD2 1 
ATOM   2555 C  CE1 . PHE A 1 397 ? 113.315 126.246 129.667 1.00 46.99  ? 397 PHE B CE1 1 
ATOM   2556 C  CE2 . PHE A 1 397 ? 112.722 124.655 127.998 1.00 46.99  ? 397 PHE B CE2 1 
ATOM   2557 C  CZ  . PHE A 1 397 ? 113.677 125.256 128.783 1.00 46.99  ? 397 PHE B CZ  1 
ATOM   2558 N  N   . LEU A 1 398 ? 106.512 126.446 130.739 1.00 51.49  ? 398 LEU B N   1 
ATOM   2559 C  CA  . LEU A 1 398 ? 105.411 127.338 131.068 1.00 51.49  ? 398 LEU B CA  1 
ATOM   2560 C  C   . LEU A 1 398 ? 104.390 126.755 132.034 1.00 51.49  ? 398 LEU B C   1 
ATOM   2561 O  O   . LEU A 1 398 ? 103.564 127.515 132.550 1.00 51.49  ? 398 LEU B O   1 
ATOM   2562 C  CB  . LEU A 1 398 ? 104.695 127.797 129.786 1.00 51.49  ? 398 LEU B CB  1 
ATOM   2563 C  CG  . LEU A 1 398 ? 104.036 126.774 128.855 1.00 51.49  ? 398 LEU B CG  1 
ATOM   2564 C  CD1 . LEU A 1 398 ? 102.630 126.401 129.295 1.00 51.49  ? 398 LEU B CD1 1 
ATOM   2565 C  CD2 . LEU A 1 398 ? 104.025 127.296 127.428 1.00 51.49  ? 398 LEU B CD2 1 
ATOM   2566 N  N   . ILE A 1 399 ? 104.409 125.454 132.290 1.00 53.70  ? 399 ILE B N   1 
ATOM   2567 C  CA  . ILE A 1 399 ? 103.462 124.869 133.246 1.00 53.70  ? 399 ILE B CA  1 
ATOM   2568 C  C   . ILE A 1 399 ? 103.787 125.377 134.646 1.00 53.70  ? 399 ILE B C   1 
ATOM   2569 O  O   . ILE A 1 399 ? 104.958 125.334 135.061 1.00 53.70  ? 399 ILE B O   1 
ATOM   2570 C  CB  . ILE A 1 399 ? 103.518 123.342 133.185 1.00 53.70  ? 399 ILE B CB  1 
ATOM   2571 C  CG1 . ILE A 1 399 ? 102.774 122.832 131.952 1.00 53.70  ? 399 ILE B CG1 1 
ATOM   2572 C  CG2 . ILE A 1 399 ? 102.923 122.733 134.440 1.00 53.70  ? 399 ILE B CG2 1 
ATOM   2573 C  CD1 . ILE A 1 399 ? 101.284 123.062 132.002 1.00 53.70  ? 399 ILE B CD1 1 
ATOM   2574 N  N   . PRO A 1 400 ? 102.806 125.873 135.404 1.00 61.37  ? 400 PRO B N   1 
ATOM   2575 C  CA  . PRO A 1 400 ? 103.087 126.409 136.745 1.00 61.37  ? 400 PRO B CA  1 
ATOM   2576 C  C   . PRO A 1 400 ? 103.329 125.286 137.742 1.00 61.37  ? 400 PRO B C   1 
ATOM   2577 O  O   . PRO A 1 400 ? 102.444 124.467 137.999 1.00 61.37  ? 400 PRO B O   1 
ATOM   2578 C  CB  . PRO A 1 400 ? 101.817 127.199 137.082 1.00 61.37  ? 400 PRO B CB  1 
ATOM   2579 C  CG  . PRO A 1 400 ? 100.746 126.530 136.294 1.00 61.37  ? 400 PRO B CG  1 
ATOM   2580 C  CD  . PRO A 1 400 ? 101.389 126.024 135.031 1.00 61.37  ? 400 PRO B CD  1 
ATOM   2581 N  N   . ALA A 1 401 ? 104.533 125.251 138.312 1.00 63.93  ? 401 ALA B N   1 
ATOM   2582 C  CA  . ALA A 1 401 ? 104.900 124.234 139.291 1.00 63.93  ? 401 ALA B CA  1 
ATOM   2583 C  C   . ALA A 1 401 ? 104.823 124.757 140.720 1.00 63.93  ? 401 ALA B C   1 
ATOM   2584 O  O   . ALA A 1 401 ? 104.075 124.221 141.543 1.00 63.93  ? 401 ALA B O   1 
ATOM   2585 C  CB  . ALA A 1 401 ? 106.310 123.710 139.001 1.00 63.93  ? 401 ALA B CB  1 
ATOM   2586 N  N   . LYS A 1 402 ? 105.582 125.804 141.029 1.00 68.84  ? 402 LYS B N   1 
ATOM   2587 C  CA  . LYS A 1 402 ? 105.670 126.345 142.377 1.00 68.84  ? 402 LYS B CA  1 
ATOM   2588 C  C   . LYS A 1 402 ? 105.300 127.820 142.351 1.00 68.84  ? 402 LYS B C   1 
ATOM   2589 O  O   . LYS A 1 402 ? 105.865 128.591 141.569 1.00 68.84  ? 402 LYS B O   1 
ATOM   2590 C  CB  . LYS A 1 402 ? 107.077 126.159 142.949 1.00 68.84  ? 402 LYS B CB  1 
ATOM   2591 C  CG  . LYS A 1 402 ? 107.201 126.492 144.424 1.00 68.84  ? 402 LYS B CG  1 
ATOM   2592 C  CD  . LYS A 1 402 ? 108.365 125.746 145.056 1.00 68.84  ? 402 LYS B CD  1 
ATOM   2593 C  CE  . LYS A 1 402 ? 108.223 124.245 144.870 1.00 68.84  ? 402 LYS B CE  1 
ATOM   2594 N  NZ  . LYS A 1 402 ? 109.188 123.485 145.710 1.00 68.84  ? 402 LYS B NZ  1 
ATOM   2595 N  N   . THR A 1 403 ? 104.361 128.208 143.208 1.00 80.12  ? 403 THR B N   1 
ATOM   2596 C  CA  . THR A 1 403 ? 103.945 129.598 143.298 1.00 80.12  ? 403 THR B CA  1 
ATOM   2597 C  C   . THR A 1 403 ? 104.968 130.401 144.099 1.00 80.12  ? 403 THR B C   1 
ATOM   2598 O  O   . THR A 1 403 ? 105.993 129.881 144.549 1.00 80.12  ? 403 THR B O   1 
ATOM   2599 C  CB  . THR A 1 403 ? 102.558 129.700 143.926 1.00 80.12  ? 403 THR B CB  1 
ATOM   2600 O  OG1 . THR A 1 403 ? 102.175 131.078 144.017 1.00 80.12  ? 403 THR B OG1 1 
ATOM   2601 C  CG2 . THR A 1 403 ? 102.560 129.089 145.317 1.00 80.12  ? 403 THR B CG2 1 
ATOM   2602 N  N   . LEU A 1 404 ? 104.681 131.689 144.273 1.00 85.48  ? 404 LEU B N   1 
ATOM   2603 C  CA  . LEU A 1 404 ? 105.538 132.599 145.031 1.00 85.48  ? 404 LEU B CA  1 
ATOM   2604 C  C   . LEU A 1 404 ? 106.965 132.619 144.487 1.00 85.48  ? 404 LEU B C   1 
ATOM   2605 O  O   . LEU A 1 404 ? 107.362 133.554 143.790 1.00 85.48  ? 404 LEU B O   1 
ATOM   2606 C  CB  . LEU A 1 404 ? 105.546 132.218 146.515 1.00 85.48  ? 404 LEU B CB  1 
ATOM   2607 C  CG  . LEU A 1 404 ? 104.205 132.313 147.245 1.00 85.48  ? 404 LEU B CG  1 
ATOM   2608 C  CD1 . LEU A 1 404 ? 104.330 131.794 148.670 1.00 85.48  ? 404 LEU B CD1 1 
ATOM   2609 C  CD2 . LEU A 1 404 ? 103.689 133.742 147.235 1.00 85.48  ? 404 LEU B CD2 1 
ATOM   2610 N  N   . GLU A 1 412 ? 106.135 139.088 152.585 1.00 102.35 ? 412 GLU B N   1 
ATOM   2611 C  CA  . GLU A 1 412 ? 105.478 137.792 152.463 1.00 102.35 ? 412 GLU B CA  1 
ATOM   2612 C  C   . GLU A 1 412 ? 104.813 137.638 151.098 1.00 102.35 ? 412 GLU B C   1 
ATOM   2613 O  O   . GLU A 1 412 ? 104.218 136.602 150.801 1.00 102.35 ? 412 GLU B O   1 
ATOM   2614 C  CB  . GLU A 1 412 ? 104.445 137.607 153.577 1.00 102.35 ? 412 GLU B CB  1 
ATOM   2615 C  CG  . GLU A 1 412 ? 103.181 138.435 153.401 1.00 102.35 ? 412 GLU B CG  1 
ATOM   2616 C  CD  . GLU A 1 412 ? 103.258 139.777 154.104 1.00 102.35 ? 412 GLU B CD  1 
ATOM   2617 O  OE1 . GLU A 1 412 ? 104.176 139.967 154.929 1.00 102.35 ? 412 GLU B OE1 1 
ATOM   2618 O  OE2 . GLU A 1 412 ? 102.400 140.643 153.832 1.00 102.35 ? 412 GLU B OE2 1 
ATOM   2619 N  N   . ILE A 1 413 ? 104.914 138.682 150.273 1.00 99.91  ? 413 ILE B N   1 
ATOM   2620 C  CA  . ILE A 1 413 ? 104.314 138.635 148.943 1.00 99.91  ? 413 ILE B CA  1 
ATOM   2621 C  C   . ILE A 1 413 ? 105.076 137.671 148.041 1.00 99.91  ? 413 ILE B C   1 
ATOM   2622 O  O   . ILE A 1 413 ? 104.471 136.892 147.294 1.00 99.91  ? 413 ILE B O   1 
ATOM   2623 C  CB  . ILE A 1 413 ? 104.243 140.050 148.339 1.00 99.91  ? 413 ILE B CB  1 
ATOM   2624 C  CG1 . ILE A 1 413 ? 105.598 140.754 148.442 1.00 99.91  ? 413 ILE B CG1 1 
ATOM   2625 C  CG2 . ILE A 1 413 ? 103.171 140.871 149.036 1.00 99.91  ? 413 ILE B CG2 1 
ATOM   2626 C  CD1 . ILE A 1 413 ? 105.662 142.068 147.695 1.00 99.91  ? 413 ILE B CD1 1 
ATOM   2627 N  N   . VAL A 1 414 ? 106.410 137.706 148.097 1.00 98.62  ? 414 VAL B N   1 
ATOM   2628 C  CA  . VAL A 1 414 ? 107.291 136.871 147.282 1.00 98.62  ? 414 VAL B CA  1 
ATOM   2629 C  C   . VAL A 1 414 ? 106.958 137.105 145.810 1.00 98.62  ? 414 VAL B C   1 
ATOM   2630 O  O   . VAL A 1 414 ? 106.963 136.175 144.995 1.00 98.62  ? 414 VAL B O   1 
ATOM   2631 C  CB  . VAL A 1 414 ? 107.177 135.383 147.679 1.00 98.62  ? 414 VAL B CB  1 
ATOM   2632 C  CG1 . VAL A 1 414 ? 108.314 134.558 147.075 1.00 98.62  ? 414 VAL B CG1 1 
ATOM   2633 C  CG2 . VAL A 1 414 ? 107.164 135.237 149.195 1.00 98.62  ? 414 VAL B CG2 1 
ATOM   2634 N  N   . ALA A 1 415 ? 106.614 138.353 145.477 1.00 97.07  ? 415 ALA B N   1 
ATOM   2635 C  CA  . ALA A 1 415 ? 106.380 138.815 144.111 1.00 97.07  ? 415 ALA B CA  1 
ATOM   2636 C  C   . ALA A 1 415 ? 105.142 138.186 143.479 1.00 97.07  ? 415 ALA B C   1 
ATOM   2637 O  O   . ALA A 1 415 ? 104.742 138.580 142.378 1.00 97.07  ? 415 ALA B O   1 
ATOM   2638 C  CB  . ALA A 1 415 ? 107.608 138.551 143.234 1.00 97.07  ? 415 ALA B CB  1 
ATOM   2639 N  N   . PHE A 1 416 ? 104.519 137.237 144.176 1.00 95.38  ? 416 PHE B N   1 
ATOM   2640 C  CA  . PHE A 1 416 ? 103.302 136.560 143.729 1.00 95.38  ? 416 PHE B CA  1 
ATOM   2641 C  C   . PHE A 1 416 ? 103.404 136.121 142.266 1.00 95.38  ? 416 PHE B C   1 
ATOM   2642 O  O   . PHE A 1 416 ? 102.618 136.519 141.406 1.00 95.38  ? 416 PHE B O   1 
ATOM   2643 C  CB  . PHE A 1 416 ? 102.077 137.448 143.957 1.00 95.38  ? 416 PHE B CB  1 
ATOM   2644 C  CG  . PHE A 1 416 ? 101.611 137.476 145.384 1.00 95.38  ? 416 PHE B CG  1 
ATOM   2645 C  CD1 . PHE A 1 416 ? 101.414 136.297 146.084 1.00 95.38  ? 416 PHE B CD1 1 
ATOM   2646 C  CD2 . PHE A 1 416 ? 101.370 138.679 146.027 1.00 95.38  ? 416 PHE B CD2 1 
ATOM   2647 C  CE1 . PHE A 1 416 ? 100.985 136.316 147.398 1.00 95.38  ? 416 PHE B CE1 1 
ATOM   2648 C  CE2 . PHE A 1 416 ? 100.941 138.704 147.342 1.00 95.38  ? 416 PHE B CE2 1 
ATOM   2649 C  CZ  . PHE A 1 416 ? 100.749 137.521 148.028 1.00 95.38  ? 416 PHE B CZ  1 
ATOM   2650 N  N   . ASP A 1 417 ? 104.404 135.285 141.998 1.00 84.63  ? 417 ASP B N   1 
ATOM   2651 C  CA  . ASP A 1 417 ? 104.629 134.729 140.672 1.00 84.63  ? 417 ASP B CA  1 
ATOM   2652 C  C   . ASP A 1 417 ? 104.914 133.240 140.792 1.00 84.63  ? 417 ASP B C   1 
ATOM   2653 O  O   . ASP A 1 417 ? 105.399 132.766 141.823 1.00 84.63  ? 417 ASP B O   1 
ATOM   2654 C  CB  . ASP A 1 417 ? 105.789 135.432 139.953 1.00 84.63  ? 417 ASP B CB  1 
ATOM   2655 C  CG  . ASP A 1 417 ? 105.693 135.322 138.444 1.00 84.63  ? 417 ASP B CG  1 
ATOM   2656 O  OD1 . ASP A 1 417 ? 105.361 134.227 137.945 1.00 84.63  ? 417 ASP B OD1 1 
ATOM   2657 O  OD2 . ASP A 1 417 ? 105.952 136.331 137.756 1.00 84.63  ? 417 ASP B OD2 1 
ATOM   2658 N  N   . TYR A 1 418 ? 104.609 132.505 139.730 1.00 70.28  ? 418 TYR B N   1 
ATOM   2659 C  CA  . TYR A 1 418 ? 104.779 131.062 139.734 1.00 70.28  ? 418 TYR B CA  1 
ATOM   2660 C  C   . TYR A 1 418 ? 106.139 130.671 139.157 1.00 70.28  ? 418 TYR B C   1 
ATOM   2661 O  O   . TYR A 1 418 ? 106.907 131.504 138.674 1.00 70.28  ? 418 TYR B O   1 
ATOM   2662 C  CB  . TYR A 1 418 ? 103.650 130.388 138.953 1.00 70.28  ? 418 TYR B CB  1 
ATOM   2663 C  CG  . TYR A 1 418 ? 103.741 130.562 137.455 1.00 70.28  ? 418 TYR B CG  1 
ATOM   2664 C  CD1 . TYR A 1 418 ? 103.182 131.665 136.830 1.00 70.28  ? 418 TYR B CD1 1 
ATOM   2665 C  CD2 . TYR A 1 418 ? 104.380 129.619 136.665 1.00 70.28  ? 418 TYR B CD2 1 
ATOM   2666 C  CE1 . TYR A 1 418 ? 103.262 131.824 135.463 1.00 70.28  ? 418 TYR B CE1 1 
ATOM   2667 C  CE2 . TYR A 1 418 ? 104.464 129.769 135.299 1.00 70.28  ? 418 TYR B CE2 1 
ATOM   2668 C  CZ  . TYR A 1 418 ? 103.905 130.873 134.703 1.00 70.28  ? 418 TYR B CZ  1 
ATOM   2669 O  OH  . TYR A 1 418 ? 103.989 131.022 133.339 1.00 70.28  ? 418 TYR B OH  1 
ATOM   2670 N  N   . SER A 1 419 ? 106.429 129.367 139.216 1.00 62.72  ? 419 SER B N   1 
ATOM   2671 C  CA  . SER A 1 419 ? 107.648 128.790 138.677 1.00 62.72  ? 419 SER B CA  1 
ATOM   2672 C  C   . SER A 1 419 ? 107.348 128.013 137.401 1.00 62.72  ? 419 SER B C   1 
ATOM   2673 O  O   . SER A 1 419 ? 106.349 127.289 137.336 1.00 62.72  ? 419 SER B O   1 
ATOM   2674 C  CB  . SER A 1 419 ? 108.314 127.857 139.694 1.00 62.72  ? 419 SER B CB  1 
ATOM   2675 O  OG  . SER A 1 419 ? 108.652 128.557 140.878 1.00 62.72  ? 419 SER B OG  1 
ATOM   2676 N  N   . PRO A 1 420 ? 108.196 128.131 136.378 1.00 53.81  ? 420 PRO B N   1 
ATOM   2677 C  CA  . PRO A 1 420 ? 107.877 127.548 135.070 1.00 53.81  ? 420 PRO B CA  1 
ATOM   2678 C  C   . PRO A 1 420 ? 108.025 126.038 134.995 1.00 53.81  ? 420 PRO B C   1 
ATOM   2679 O  O   . PRO A 1 420 ? 107.849 125.484 133.905 1.00 53.81  ? 420 PRO B O   1 
ATOM   2680 C  CB  . PRO A 1 420 ? 108.887 128.235 134.131 1.00 53.81  ? 420 PRO B CB  1 
ATOM   2681 C  CG  . PRO A 1 420 ? 109.524 129.335 134.940 1.00 53.81  ? 420 PRO B CG  1 
ATOM   2682 C  CD  . PRO A 1 420 ? 109.463 128.874 136.351 1.00 53.81  ? 420 PRO B CD  1 
ATOM   2683 N  N   . LEU A 1 421 ? 108.364 125.377 136.107 1.00 50.01  ? 421 LEU B N   1 
ATOM   2684 C  CA  . LEU A 1 421 ? 108.606 123.936 136.208 1.00 50.01  ? 421 LEU B CA  1 
ATOM   2685 C  C   . LEU A 1 421 ? 109.944 123.561 135.577 1.00 50.01  ? 421 LEU B C   1 
ATOM   2686 O  O   . LEU A 1 421 ? 110.458 122.464 135.814 1.00 50.01  ? 421 LEU B O   1 
ATOM   2687 C  CB  . LEU A 1 421 ? 107.455 123.146 135.566 1.00 50.01  ? 421 LEU B CB  1 
ATOM   2688 C  CG  . LEU A 1 421 ? 107.461 121.618 135.490 1.00 50.01  ? 421 LEU B CG  1 
ATOM   2689 C  CD1 . LEU A 1 421 ? 107.355 121.003 136.866 1.00 50.01  ? 421 LEU B CD1 1 
ATOM   2690 C  CD2 . LEU A 1 421 ? 106.327 121.132 134.611 1.00 50.01  ? 421 LEU B CD2 1 
ATOM   2691 N  N   . ILE A 1 422 ? 110.543 124.499 134.842 1.00 49.17  ? 422 ILE B N   1 
ATOM   2692 C  CA  . ILE A 1 422 ? 111.892 124.419 134.285 1.00 49.17  ? 422 ILE B CA  1 
ATOM   2693 C  C   . ILE A 1 422 ? 112.389 125.845 134.098 1.00 49.17  ? 422 ILE B C   1 
ATOM   2694 O  O   . ILE A 1 422 ? 111.685 126.687 133.531 1.00 49.17  ? 422 ILE B O   1 
ATOM   2695 C  CB  . ILE A 1 422 ? 111.954 123.659 132.943 1.00 49.17  ? 422 ILE B CB  1 
ATOM   2696 C  CG1 . ILE A 1 422 ? 111.656 122.170 133.098 1.00 49.17  ? 422 ILE B CG1 1 
ATOM   2697 C  CG2 . ILE A 1 422 ? 113.318 123.825 132.299 1.00 49.17  ? 422 ILE B CG2 1 
ATOM   2698 C  CD1 . ILE A 1 422 ? 112.701 121.439 133.903 1.00 49.17  ? 422 ILE B CD1 1 
ATOM   2699 N  N   . THR A 1 423 ? 113.597 126.130 134.563 1.00 52.07  ? 423 THR B N   1 
ATOM   2700 C  CA  . THR A 1 423 ? 114.231 127.413 134.313 1.00 52.07  ? 423 THR B CA  1 
ATOM   2701 C  C   . THR A 1 423 ? 115.275 127.256 133.216 1.00 52.07  ? 423 THR B C   1 
ATOM   2702 O  O   . THR A 1 423 ? 115.908 126.206 133.086 1.00 52.07  ? 423 THR B O   1 
ATOM   2703 C  CB  . THR A 1 423 ? 114.881 127.964 135.583 1.00 52.07  ? 423 THR B CB  1 
ATOM   2704 O  OG1 . THR A 1 423 ? 116.005 127.151 135.936 1.00 52.07  ? 423 THR B OG1 1 
ATOM   2705 C  CG2 . THR A 1 423 ? 113.885 127.962 136.728 1.00 52.07  ? 423 THR B CG2 1 
ATOM   2706 N  N   . TRP A 1 424 ? 115.441 128.310 132.413 1.00 51.79  ? 424 TRP B N   1 
ATOM   2707 C  CA  . TRP A 1 424 ? 116.386 128.230 131.305 1.00 51.79  ? 424 TRP B CA  1 
ATOM   2708 C  C   . TRP A 1 424 ? 117.812 128.021 131.792 1.00 51.79  ? 424 TRP B C   1 
ATOM   2709 O  O   . TRP A 1 424 ? 118.625 127.419 131.084 1.00 51.79  ? 424 TRP B O   1 
ATOM   2710 C  CB  . TRP A 1 424 ? 116.310 129.484 130.438 1.00 51.79  ? 424 TRP B CB  1 
ATOM   2711 C  CG  . TRP A 1 424 ? 117.311 129.455 129.333 1.00 51.79  ? 424 TRP B CG  1 
ATOM   2712 C  CD1 . TRP A 1 424 ? 118.494 130.130 129.283 1.00 51.79  ? 424 TRP B CD1 1 
ATOM   2713 C  CD2 . TRP A 1 424 ? 117.236 128.686 128.129 1.00 51.79  ? 424 TRP B CD2 1 
ATOM   2714 N  NE1 . TRP A 1 424 ? 119.155 129.840 128.114 1.00 51.79  ? 424 TRP B NE1 1 
ATOM   2715 C  CE2 . TRP A 1 424 ? 118.403 128.955 127.389 1.00 51.79  ? 424 TRP B CE2 1 
ATOM   2716 C  CE3 . TRP A 1 424 ? 116.292 127.802 127.601 1.00 51.79  ? 424 TRP B CE3 1 
ATOM   2717 C  CZ2 . TRP A 1 424 ? 118.651 128.372 126.150 1.00 51.79  ? 424 TRP B CZ2 1 
ATOM   2718 C  CZ3 . TRP A 1 424 ? 116.539 127.226 126.372 1.00 51.79  ? 424 TRP B CZ3 1 
ATOM   2719 C  CH2 . TRP A 1 424 ? 117.709 127.511 125.661 1.00 51.79  ? 424 TRP B CH2 1 
ATOM   2720 N  N   . LYS A 1 425 ? 118.140 128.509 132.989 1.00 52.82  ? 425 LYS B N   1 
ATOM   2721 C  CA  . LYS A 1 425 ? 119.468 128.251 133.534 1.00 52.82  ? 425 LYS B CA  1 
ATOM   2722 C  C   . LYS A 1 425 ? 119.664 126.775 133.853 1.00 52.82  ? 425 LYS B C   1 
ATOM   2723 O  O   . LYS A 1 425 ? 120.797 126.282 133.823 1.00 52.82  ? 425 LYS B O   1 
ATOM   2724 C  CB  . LYS A 1 425 ? 119.705 129.127 134.768 1.00 52.82  ? 425 LYS B CB  1 
ATOM   2725 C  CG  . LYS A 1 425 ? 118.754 128.890 135.936 1.00 52.82  ? 425 LYS B CG  1 
ATOM   2726 C  CD  . LYS A 1 425 ? 119.303 127.890 136.941 1.00 52.82  ? 425 LYS B CD  1 
ATOM   2727 C  CE  . LYS A 1 425 ? 118.391 127.770 138.150 1.00 52.82  ? 425 LYS B CE  1 
ATOM   2728 N  NZ  . LYS A 1 425 ? 118.906 126.782 139.137 1.00 52.82  ? 425 LYS B NZ  1 
ATOM   2729 N  N   . GLU A 1 426 ? 118.582 126.056 134.160 1.00 54.84  ? 426 GLU B N   1 
ATOM   2730 C  CA  . GLU A 1 426 ? 118.683 124.616 134.376 1.00 54.84  ? 426 GLU B CA  1 
ATOM   2731 C  C   . GLU A 1 426 ? 118.799 123.858 133.060 1.00 54.84  ? 426 GLU B C   1 
ATOM   2732 O  O   . GLU A 1 426 ? 119.499 122.843 132.987 1.00 54.84  ? 426 GLU B O   1 
ATOM   2733 C  CB  . GLU A 1 426 ? 117.483 124.118 135.179 1.00 54.84  ? 426 GLU B CB  1 
ATOM   2734 C  CG  . GLU A 1 426 ? 117.549 124.478 136.652 1.00 54.84  ? 426 GLU B CG  1 
ATOM   2735 C  CD  . GLU A 1 426 ? 116.243 124.236 137.372 1.00 54.84  ? 426 GLU B CD  1 
ATOM   2736 O  OE1 . GLU A 1 426 ? 115.901 123.058 137.599 1.00 54.84  ? 426 GLU B OE1 1 
ATOM   2737 O  OE2 . GLU A 1 426 ? 115.557 125.221 137.711 1.00 54.84  ? 426 GLU B OE2 1 
ATOM   2738 N  N   . PHE A 1 427 ? 118.120 124.330 132.013 1.00 49.65  ? 427 PHE B N   1 
ATOM   2739 C  CA  . PHE A 1 427 ? 118.268 123.715 130.700 1.00 49.65  ? 427 PHE B CA  1 
ATOM   2740 C  C   . PHE A 1 427 ? 119.613 124.041 130.065 1.00 49.65  ? 427 PHE B C   1 
ATOM   2741 O  O   . PHE A 1 427 ? 120.055 123.311 129.172 1.00 49.65  ? 427 PHE B O   1 
ATOM   2742 C  CB  . PHE A 1 427 ? 117.130 124.157 129.781 1.00 49.65  ? 427 PHE B CB  1 
ATOM   2743 C  CG  . PHE A 1 427 ? 117.170 123.525 128.423 1.00 49.65  ? 427 PHE B CG  1 
ATOM   2744 C  CD1 . PHE A 1 427 ? 116.653 122.262 128.217 1.00 49.65  ? 427 PHE B CD1 1 
ATOM   2745 C  CD2 . PHE A 1 427 ? 117.720 124.199 127.348 1.00 49.65  ? 427 PHE B CD2 1 
ATOM   2746 C  CE1 . PHE A 1 427 ? 116.689 121.682 126.968 1.00 49.65  ? 427 PHE B CE1 1 
ATOM   2747 C  CE2 . PHE A 1 427 ? 117.757 123.622 126.098 1.00 49.65  ? 427 PHE B CE2 1 
ATOM   2748 C  CZ  . PHE A 1 427 ? 117.241 122.363 125.909 1.00 49.65  ? 427 PHE B CZ  1 
ATOM   2749 N  N   . GLN A 1 428 ? 120.267 125.118 130.502 1.00 57.47  ? 428 GLN B N   1 
ATOM   2750 C  CA  . GLN A 1 428 ? 121.616 125.407 130.028 1.00 57.47  ? 428 GLN B CA  1 
ATOM   2751 C  C   . GLN A 1 428 ? 122.569 124.280 130.400 1.00 57.47  ? 428 GLN B C   1 
ATOM   2752 O  O   . GLN A 1 428 ? 123.428 123.892 129.600 1.00 57.47  ? 428 GLN B O   1 
ATOM   2753 C  CB  . GLN A 1 428 ? 122.101 126.735 130.606 1.00 57.47  ? 428 GLN B CB  1 
ATOM   2754 C  CG  . GLN A 1 428 ? 123.350 127.287 129.944 1.00 57.47  ? 428 GLN B CG  1 
ATOM   2755 C  CD  . GLN A 1 428 ? 123.041 128.347 128.907 1.00 57.47  ? 428 GLN B CD  1 
ATOM   2756 O  OE1 . GLN A 1 428 ? 121.900 128.786 128.773 1.00 57.47  ? 428 GLN B OE1 1 
ATOM   2757 N  NE2 . GLN A 1 428 ? 124.062 128.767 128.168 1.00 57.47  ? 428 GLN B NE2 1 
ATOM   2758 N  N   . SER A 1 429 ? 122.437 123.750 131.613 1.00 57.57  ? 429 SER B N   1 
ATOM   2759 C  CA  . SER A 1 429 ? 123.117 122.525 131.991 1.00 57.57  ? 429 SER B CA  1 
ATOM   2760 C  C   . SER A 1 429 ? 122.308 121.327 131.505 1.00 57.57  ? 429 SER B C   1 
ATOM   2761 O  O   . SER A 1 429 ? 121.248 121.469 130.890 1.00 57.57  ? 429 SER B O   1 
ATOM   2762 C  CB  . SER A 1 429 ? 123.323 122.471 133.502 1.00 57.57  ? 429 SER B CB  1 
ATOM   2763 O  OG  . SER A 1 429 ? 122.083 122.524 134.183 1.00 57.57  ? 429 SER B OG  1 
ATOM   2764 N  N   . PHE A 1 430 ? 122.814 120.127 131.776 1.00 59.24  ? 430 PHE B N   1 
ATOM   2765 C  CA  . PHE A 1 430 ? 122.181 118.868 131.392 1.00 59.24  ? 430 PHE B CA  1 
ATOM   2766 C  C   . PHE A 1 430 ? 121.989 118.744 129.886 1.00 59.24  ? 430 PHE B C   1 
ATOM   2767 O  O   . PHE A 1 430 ? 121.202 117.904 129.436 1.00 59.24  ? 430 PHE B O   1 
ATOM   2768 C  CB  . PHE A 1 430 ? 120.824 118.669 132.092 1.00 59.24  ? 430 PHE B CB  1 
ATOM   2769 C  CG  . PHE A 1 430 ? 120.883 118.721 133.598 1.00 59.24  ? 430 PHE B CG  1 
ATOM   2770 C  CD1 . PHE A 1 430 ? 122.092 118.729 134.276 1.00 59.24  ? 430 PHE B CD1 1 
ATOM   2771 C  CD2 . PHE A 1 430 ? 119.713 118.776 134.335 1.00 59.24  ? 430 PHE B CD2 1 
ATOM   2772 C  CE1 . PHE A 1 430 ? 122.130 118.782 135.657 1.00 59.24  ? 430 PHE B CE1 1 
ATOM   2773 C  CE2 . PHE A 1 430 ? 119.744 118.832 135.712 1.00 59.24  ? 430 PHE B CE2 1 
ATOM   2774 C  CZ  . PHE A 1 430 ? 120.954 118.833 136.375 1.00 59.24  ? 430 PHE B CZ  1 
ATOM   2775 N  N   . MET A 1 431 ? 122.684 119.559 129.092 1.00 57.94  ? 431 MET B N   1 
ATOM   2776 C  CA  . MET A 1 431 ? 122.462 119.610 127.660 1.00 57.94  ? 431 MET B CA  1 
ATOM   2777 C  C   . MET A 1 431 ? 123.755 119.341 126.898 1.00 57.94  ? 431 MET B C   1 
ATOM   2778 O  O   . MET A 1 431 ? 124.818 119.836 127.287 1.00 57.94  ? 431 MET B O   1 
ATOM   2779 C  CB  . MET A 1 431 ? 121.896 120.978 127.254 1.00 57.94  ? 431 MET B CB  1 
ATOM   2780 C  CG  . MET A 1 431 ? 121.705 121.152 125.767 1.00 57.94  ? 431 MET B CG  1 
ATOM   2781 S  SD  . MET A 1 431 ? 120.139 120.522 125.150 1.00 57.94  ? 431 MET B SD  1 
ATOM   2782 C  CE  . MET A 1 431 ? 120.354 120.737 123.389 1.00 57.94  ? 431 MET B CE  1 
ATOM   2783 N  N   . PRO A 1 432 ? 123.700 118.560 125.813 1.00 58.79  ? 432 PRO B N   1 
ATOM   2784 C  CA  . PRO A 1 432 ? 124.909 118.221 125.039 1.00 58.79  ? 432 PRO B CA  1 
ATOM   2785 C  C   . PRO A 1 432 ? 125.338 119.323 124.073 1.00 58.79  ? 432 PRO B C   1 
ATOM   2786 O  O   . PRO A 1 432 ? 125.330 119.159 122.850 1.00 58.79  ? 432 PRO B O   1 
ATOM   2787 C  CB  . PRO A 1 432 ? 124.479 116.939 124.317 1.00 58.79  ? 432 PRO B CB  1 
ATOM   2788 C  CG  . PRO A 1 432 ? 123.032 117.084 124.135 1.00 58.79  ? 432 PRO B CG  1 
ATOM   2789 C  CD  . PRO A 1 432 ? 122.517 117.827 125.328 1.00 58.79  ? 432 PRO B CD  1 
ATOM   2790 N  N   . TRP A 1 433 ? 125.722 120.467 124.630 1.00 62.82  ? 433 TRP B N   1 
ATOM   2791 C  CA  . TRP A 1 433 ? 126.370 121.549 123.894 1.00 62.82  ? 433 TRP B CA  1 
ATOM   2792 C  C   . TRP A 1 433 ? 127.880 121.391 123.765 1.00 62.82  ? 433 TRP B C   1 
ATOM   2793 O  O   . TRP A 1 433 ? 128.521 122.258 123.164 1.00 62.82  ? 433 TRP B O   1 
ATOM   2794 C  CB  . TRP A 1 433 ? 125.997 122.892 124.534 1.00 62.82  ? 433 TRP B CB  1 
ATOM   2795 C  CG  . TRP A 1 433 ? 124.554 123.251 124.309 1.00 62.82  ? 433 TRP B CG  1 
ATOM   2796 C  CD1 . TRP A 1 433 ? 123.679 122.603 123.492 1.00 62.82  ? 433 TRP B CD1 1 
ATOM   2797 C  CD2 . TRP A 1 433 ? 123.793 124.273 124.972 1.00 62.82  ? 433 TRP B CD2 1 
ATOM   2798 N  NE1 . TRP A 1 433 ? 122.446 123.200 123.543 1.00 62.82  ? 433 TRP B NE1 1 
ATOM   2799 C  CE2 . TRP A 1 433 ? 122.484 124.217 124.459 1.00 62.82  ? 433 TRP B CE2 1 
ATOM   2800 C  CE3 . TRP A 1 433 ? 124.093 125.237 125.933 1.00 62.82  ? 433 TRP B CE3 1 
ATOM   2801 C  CZ2 . TRP A 1 433 ? 121.482 125.087 124.874 1.00 62.82  ? 433 TRP B CZ2 1 
ATOM   2802 C  CZ3 . TRP A 1 433 ? 123.100 126.103 126.341 1.00 62.82  ? 433 TRP B CZ3 1 
ATOM   2803 C  CH2 . TRP A 1 433 ? 121.809 126.022 125.814 1.00 62.82  ? 433 TRP B CH2 1 
ATOM   2804 N  N   . ASP A 1 434 ? 128.466 120.319 124.296 1.00 60.20  ? 434 ASP B N   1 
ATOM   2805 C  CA  . ASP A 1 434 ? 129.867 120.032 124.008 1.00 60.20  ? 434 ASP B CA  1 
ATOM   2806 C  C   . ASP A 1 434 ? 130.049 118.983 122.914 1.00 60.20  ? 434 ASP B C   1 
ATOM   2807 O  O   . ASP A 1 434 ? 131.073 119.001 122.218 1.00 60.20  ? 434 ASP B O   1 
ATOM   2808 C  CB  . ASP A 1 434 ? 130.600 119.616 125.290 1.00 60.20  ? 434 ASP B CB  1 
ATOM   2809 C  CG  . ASP A 1 434 ? 129.814 118.629 126.124 1.00 60.20  ? 434 ASP B CG  1 
ATOM   2810 O  OD1 . ASP A 1 434 ? 129.171 117.738 125.547 1.00 60.20  ? 434 ASP B OD1 1 
ATOM   2811 O  OD2 . ASP A 1 434 ? 129.840 118.749 127.368 1.00 60.20  ? 434 ASP B OD2 1 
ATOM   2812 N  N   . ILE A 1 435 ? 129.081 118.080 122.728 1.00 60.78  ? 435 ILE B N   1 
ATOM   2813 C  CA  . ILE A 1 435 ? 129.114 117.194 121.564 1.00 60.78  ? 435 ILE B CA  1 
ATOM   2814 C  C   . ILE A 1 435 ? 129.018 117.986 120.266 1.00 60.78  ? 435 ILE B C   1 
ATOM   2815 O  O   . ILE A 1 435 ? 129.573 117.576 119.240 1.00 60.78  ? 435 ILE B O   1 
ATOM   2816 C  CB  . ILE A 1 435 ? 128.020 116.104 121.650 1.00 60.78  ? 435 ILE B CB  1 
ATOM   2817 C  CG1 . ILE A 1 435 ? 128.243 115.169 122.846 1.00 60.78  ? 435 ILE B CG1 1 
ATOM   2818 C  CG2 . ILE A 1 435 ? 127.920 115.311 120.362 1.00 60.78  ? 435 ILE B CG2 1 
ATOM   2819 C  CD1 . ILE A 1 435 ? 127.616 115.587 124.132 1.00 60.78  ? 435 ILE B CD1 1 
ATOM   2820 N  N   . ALA A 1 436 ? 128.329 119.129 120.280 1.00 64.39  ? 436 ALA B N   1 
ATOM   2821 C  CA  . ALA A 1 436 ? 128.278 119.964 119.083 1.00 64.39  ? 436 ALA B CA  1 
ATOM   2822 C  C   . ALA A 1 436 ? 129.675 120.417 118.673 1.00 64.39  ? 436 ALA B C   1 
ATOM   2823 O  O   . ALA A 1 436 ? 130.079 120.260 117.514 1.00 64.39  ? 436 ALA B O   1 
ATOM   2824 C  CB  . ALA A 1 436 ? 127.366 121.167 119.323 1.00 64.39  ? 436 ALA B CB  1 
ATOM   2825 N  N   . ILE A 1 437 ? 130.438 120.959 119.624 1.00 62.97  ? 437 ILE B N   1 
ATOM   2826 C  CA  . ILE A 1 437 ? 131.804 121.387 119.333 1.00 62.97  ? 437 ILE B CA  1 
ATOM   2827 C  C   . ILE A 1 437 ? 132.672 120.189 118.975 1.00 62.97  ? 437 ILE B C   1 
ATOM   2828 O  O   . ILE A 1 437 ? 133.570 120.284 118.130 1.00 62.97  ? 437 ILE B O   1 
ATOM   2829 C  CB  . ILE A 1 437 ? 132.384 122.167 120.526 1.00 62.97  ? 437 ILE B CB  1 
ATOM   2830 C  CG1 . ILE A 1 437 ? 131.364 123.183 121.045 1.00 62.97  ? 437 ILE B CG1 1 
ATOM   2831 C  CG2 . ILE A 1 437 ? 133.679 122.856 120.134 1.00 62.97  ? 437 ILE B CG2 1 
ATOM   2832 C  CD1 . ILE A 1 437 ? 131.882 124.045 122.173 1.00 62.97  ? 437 ILE B CD1 1 
ATOM   2833 N  N   . LEU A 1 438 ? 132.428 119.046 119.618 1.00 62.25  ? 438 LEU B N   1 
ATOM   2834 C  CA  . LEU A 1 438 ? 133.219 117.853 119.334 1.00 62.25  ? 438 LEU B CA  1 
ATOM   2835 C  C   . LEU A 1 438 ? 133.041 117.404 117.887 1.00 62.25  ? 438 LEU B C   1 
ATOM   2836 O  O   . LEU A 1 438 ? 134.021 117.163 117.170 1.00 62.25  ? 438 LEU B O   1 
ATOM   2837 C  CB  . LEU A 1 438 ? 132.830 116.739 120.306 1.00 62.25  ? 438 LEU B CB  1 
ATOM   2838 C  CG  . LEU A 1 438 ? 133.779 115.553 120.454 1.00 62.25  ? 438 LEU B CG  1 
ATOM   2839 C  CD1 . LEU A 1 438 ? 133.738 115.038 121.878 1.00 62.25  ? 438 LEU B CD1 1 
ATOM   2840 C  CD2 . LEU A 1 438 ? 133.402 114.454 119.489 1.00 62.25  ? 438 LEU B CD2 1 
ATOM   2841 N  N   . VAL A 1 439 ? 131.791 117.290 117.436 1.00 68.45  ? 439 VAL B N   1 
ATOM   2842 C  CA  . VAL A 1 439 ? 131.543 116.866 116.063 1.00 68.45  ? 439 VAL B CA  1 
ATOM   2843 C  C   . VAL A 1 439 ? 131.982 117.947 115.084 1.00 68.45  ? 439 VAL B C   1 
ATOM   2844 O  O   . VAL A 1 439 ? 132.382 117.643 113.954 1.00 68.45  ? 439 VAL B O   1 
ATOM   2845 C  CB  . VAL A 1 439 ? 130.065 116.472 115.871 1.00 68.45  ? 439 VAL B CB  1 
ATOM   2846 C  CG1 . VAL A 1 439 ? 129.152 117.677 115.996 1.00 68.45  ? 439 VAL B CG1 1 
ATOM   2847 C  CG2 . VAL A 1 439 ? 129.870 115.773 114.536 1.00 68.45  ? 439 VAL B CG2 1 
ATOM   2848 N  N   . GLY A 1 440 ? 131.936 119.219 115.490 1.00 74.69  ? 440 GLY B N   1 
ATOM   2849 C  CA  . GLY A 1 440 ? 132.483 120.264 114.641 1.00 74.69  ? 440 GLY B CA  1 
ATOM   2850 C  C   . GLY A 1 440 ? 133.979 120.124 114.436 1.00 74.69  ? 440 GLY B C   1 
ATOM   2851 O  O   . GLY A 1 440 ? 134.481 120.278 113.320 1.00 74.69  ? 440 GLY B O   1 
ATOM   2852 N  N   . GLY A 1 441 ? 134.711 119.834 115.511 1.00 71.78  ? 441 GLY B N   1 
ATOM   2853 C  CA  . GLY A 1 441 ? 136.134 119.576 115.373 1.00 71.78  ? 441 GLY B CA  1 
ATOM   2854 C  C   . GLY A 1 441 ? 136.415 118.341 114.541 1.00 71.78  ? 441 GLY B C   1 
ATOM   2855 O  O   . GLY A 1 441 ? 137.377 118.304 113.770 1.00 71.78  ? 441 GLY B O   1 
ATOM   2856 N  N   . GLY A 1 442 ? 135.580 117.312 114.688 1.00 72.20  ? 442 GLY B N   1 
ATOM   2857 C  CA  . GLY A 1 442 ? 135.710 116.144 113.833 1.00 72.20  ? 442 GLY B CA  1 
ATOM   2858 C  C   . GLY A 1 442 ? 135.533 116.481 112.364 1.00 72.20  ? 442 GLY B C   1 
ATOM   2859 O  O   . GLY A 1 442 ? 136.295 116.016 111.514 1.00 72.20  ? 442 GLY B O   1 
ATOM   2860 N  N   . PHE A 1 443 ? 134.528 117.302 112.050 1.00 77.42  ? 443 PHE B N   1 
ATOM   2861 C  CA  . PHE A 1 443 ? 134.329 117.750 110.674 1.00 77.42  ? 443 PHE B CA  1 
ATOM   2862 C  C   . PHE A 1 443 ? 135.520 118.553 110.177 1.00 77.42  ? 443 PHE B C   1 
ATOM   2863 O  O   . PHE A 1 443 ? 135.949 118.393 109.029 1.00 77.42  ? 443 PHE B O   1 
ATOM   2864 C  CB  . PHE A 1 443 ? 133.057 118.589 110.566 1.00 77.42  ? 443 PHE B CB  1 
ATOM   2865 C  CG  . PHE A 1 443 ? 131.793 117.812 110.770 1.00 77.42  ? 443 PHE B CG  1 
ATOM   2866 C  CD1 . PHE A 1 443 ? 131.796 116.430 110.727 1.00 77.42  ? 443 PHE B CD1 1 
ATOM   2867 C  CD2 . PHE A 1 443 ? 130.599 118.469 111.012 1.00 77.42  ? 443 PHE B CD2 1 
ATOM   2868 C  CE1 . PHE A 1 443 ? 130.631 115.719 110.914 1.00 77.42  ? 443 PHE B CE1 1 
ATOM   2869 C  CE2 . PHE A 1 443 ? 129.430 117.762 111.202 1.00 77.42  ? 443 PHE B CE2 1 
ATOM   2870 C  CZ  . PHE A 1 443 ? 129.446 116.386 111.152 1.00 77.42  ? 443 PHE B CZ  1 
ATOM   2871 N  N   . ALA A 1 444 ? 136.054 119.440 111.018 1.00 78.35  ? 444 ALA B N   1 
ATOM   2872 C  CA  . ALA A 1 444 ? 137.198 120.249 110.610 1.00 78.35  ? 444 ALA B CA  1 
ATOM   2873 C  C   . ALA A 1 444 ? 138.403 119.371 110.302 1.00 78.35  ? 444 ALA B C   1 
ATOM   2874 O  O   . ALA A 1 444 ? 139.087 119.564 109.291 1.00 78.35  ? 444 ALA B O   1 
ATOM   2875 C  CB  . ALA A 1 444 ? 137.534 121.270 111.696 1.00 78.35  ? 444 ALA B CB  1 
ATOM   2876 N  N   . LEU A 1 445 ? 138.670 118.387 111.163 1.00 77.50  ? 445 LEU B N   1 
ATOM   2877 C  CA  . LEU A 1 445 ? 139.803 117.496 110.937 1.00 77.50  ? 445 LEU B CA  1 
ATOM   2878 C  C   . LEU A 1 445 ? 139.597 116.638 109.696 1.00 77.50  ? 445 LEU B C   1 
ATOM   2879 O  O   . LEU A 1 445 ? 140.537 116.417 108.924 1.00 77.50  ? 445 LEU B O   1 
ATOM   2880 C  CB  . LEU A 1 445 ? 140.036 116.618 112.165 1.00 77.50  ? 445 LEU B CB  1 
ATOM   2881 C  CG  . LEU A 1 445 ? 141.429 115.999 112.271 1.00 77.50  ? 445 LEU B CG  1 
ATOM   2882 C  CD1 . LEU A 1 445 ? 142.497 117.063 112.098 1.00 77.50  ? 445 LEU B CD1 1 
ATOM   2883 C  CD2 . LEU A 1 445 ? 141.594 115.279 113.598 1.00 77.50  ? 445 LEU B CD2 1 
ATOM   2884 N  N   . ALA A 1 446 ? 138.376 116.138 109.488 1.00 82.97  ? 446 ALA B N   1 
ATOM   2885 C  CA  . ALA A 1 446 ? 138.105 115.328 108.306 1.00 82.97  ? 446 ALA B CA  1 
ATOM   2886 C  C   . ALA A 1 446 ? 138.258 116.143 107.029 1.00 82.97  ? 446 ALA B C   1 
ATOM   2887 O  O   . ALA A 1 446 ? 138.856 115.674 106.054 1.00 82.97  ? 446 ALA B O   1 
ATOM   2888 C  CB  . ALA A 1 446 ? 136.704 114.725 108.393 1.00 82.97  ? 446 ALA B CB  1 
ATOM   2889 N  N   . ASP A 1 447 ? 137.732 117.371 107.018 1.00 91.82  ? 447 ASP B N   1 
ATOM   2890 C  CA  . ASP A 1 447 ? 137.864 118.230 105.847 1.00 91.82  ? 447 ASP B CA  1 
ATOM   2891 C  C   . ASP A 1 447 ? 139.313 118.622 105.605 1.00 91.82  ? 447 ASP B C   1 
ATOM   2892 O  O   . ASP A 1 447 ? 139.726 118.777 104.450 1.00 91.82  ? 447 ASP B O   1 
ATOM   2893 C  CB  . ASP A 1 447 ? 136.994 119.476 106.009 1.00 91.82  ? 447 ASP B CB  1 
ATOM   2894 C  CG  . ASP A 1 447 ? 136.545 120.050 104.679 1.00 91.82  ? 447 ASP B CG  1 
ATOM   2895 O  OD1 . ASP A 1 447 ? 137.189 119.752 103.651 1.00 91.82  ? 447 ASP B OD1 1 
ATOM   2896 O  OD2 . ASP A 1 447 ? 135.546 120.800 104.661 1.00 91.82  ? 447 ASP B OD2 1 
ATOM   2897 N  N   . GLY A 1 448 ? 140.095 118.795 106.672 1.00 90.34  ? 448 GLY B N   1 
ATOM   2898 C  CA  . GLY A 1 448 ? 141.524 118.986 106.496 1.00 90.34  ? 448 GLY B CA  1 
ATOM   2899 C  C   . GLY A 1 448 ? 142.172 117.811 105.793 1.00 90.34  ? 448 GLY B C   1 
ATOM   2900 O  O   . GLY A 1 448 ? 143.091 117.983 104.989 1.00 90.34  ? 448 GLY B O   1 
ATOM   2901 N  N   . CYS A 1 449 ? 141.698 116.602 106.080 1.00 94.74  ? 449 CYS B N   1 
ATOM   2902 C  CA  . CYS A 1 449 ? 142.164 115.401 105.392 1.00 94.74  ? 449 CYS B CA  1 
ATOM   2903 C  C   . CYS A 1 449 ? 141.308 115.100 104.166 1.00 94.74  ? 449 CYS B C   1 
ATOM   2904 O  O   . CYS A 1 449 ? 140.849 113.977 103.962 1.00 94.74  ? 449 CYS B O   1 
ATOM   2905 C  CB  . CYS A 1 449 ? 142.167 114.221 106.357 1.00 94.74  ? 449 CYS B CB  1 
ATOM   2906 S  SG  . CYS A 1 449 ? 143.232 114.438 107.794 1.00 94.74  ? 449 CYS B SG  1 
ATOM   2907 N  N   . GLU A 1 450 ? 141.092 116.116 103.333 1.00 97.76  ? 450 GLU B N   1 
ATOM   2908 C  CA  . GLU A 1 450 ? 140.394 115.943 102.065 1.00 97.76  ? 450 GLU B CA  1 
ATOM   2909 C  C   . GLU A 1 450 ? 141.170 116.650 100.966 1.00 97.76  ? 450 GLU B C   1 
ATOM   2910 O  O   . GLU A 1 450 ? 141.036 116.320 99.783  1.00 97.76  ? 450 GLU B O   1 
ATOM   2911 C  CB  . GLU A 1 450 ? 138.962 116.477 102.144 1.00 97.76  ? 450 GLU B CB  1 
ATOM   2912 C  CG  . GLU A 1 450 ? 138.039 115.663 103.036 1.00 97.76  ? 450 GLU B CG  1 
ATOM   2913 C  CD  . GLU A 1 450 ? 136.634 115.551 102.478 1.00 97.76  ? 450 GLU B CD  1 
ATOM   2914 O  OE1 . GLU A 1 450 ? 136.478 115.013 101.362 1.00 97.76  ? 450 GLU B OE1 1 
ATOM   2915 O  OE2 . GLU A 1 450 ? 135.684 115.999 103.155 1.00 97.76  ? 450 GLU B OE2 1 
ATOM   2916 N  N   . GLU A 1 451 ? 141.984 117.623 101.353 1.00 99.72  ? 451 GLU B N   1 
ATOM   2917 C  CA  . GLU A 1 451 ? 142.867 118.336 100.445 1.00 99.72  ? 451 GLU B CA  1 
ATOM   2918 C  C   . GLU A 1 451 ? 144.309 117.938 100.752 1.00 99.72  ? 451 GLU B C   1 
ATOM   2919 O  O   . GLU A 1 451 ? 144.564 117.034 101.554 1.00 99.72  ? 451 GLU B O   1 
ATOM   2920 C  CB  . GLU A 1 451 ? 142.647 119.847 100.544 1.00 99.72  ? 451 GLU B CB  1 
ATOM   2921 C  CG  . GLU A 1 451 ? 143.214 120.494 101.790 1.00 99.72  ? 451 GLU B CG  1 
ATOM   2922 C  CD  . GLU A 1 451 ? 143.065 122.001 101.769 1.00 99.72  ? 451 GLU B CD  1 
ATOM   2923 O  OE1 . GLU A 1 451 ? 141.930 122.484 101.571 1.00 99.72  ? 451 GLU B OE1 1 
ATOM   2924 O  OE2 . GLU A 1 451 ? 144.083 122.703 101.942 1.00 99.72  ? 451 GLU B OE2 1 
ATOM   2925 N  N   . SER A 1 452 ? 145.249 118.614 100.091 1.00 99.44  ? 452 SER B N   1 
ATOM   2926 C  CA  . SER A 1 452 ? 146.660 118.246 100.123 1.00 99.44  ? 452 SER B CA  1 
ATOM   2927 C  C   . SER A 1 452 ? 146.831 116.856 99.523  1.00 99.44  ? 452 SER B C   1 
ATOM   2928 O  O   . SER A 1 452 ? 146.403 116.612 98.390  1.00 99.44  ? 452 SER B O   1 
ATOM   2929 C  CB  . SER A 1 452 ? 147.221 118.311 101.548 1.00 99.44  ? 452 SER B CB  1 
ATOM   2930 O  OG  . SER A 1 452 ? 148.433 117.586 101.653 1.00 99.44  ? 452 SER B OG  1 
ATOM   2931 N  N   . GLY A 1 453 ? 147.454 115.941 100.258 1.00 100.51 ? 453 GLY B N   1 
ATOM   2932 C  CA  . GLY A 1 453 ? 147.635 114.597 99.748  1.00 100.51 ? 453 GLY B CA  1 
ATOM   2933 C  C   . GLY A 1 453 ? 147.554 113.516 100.804 1.00 100.51 ? 453 GLY B C   1 
ATOM   2934 O  O   . GLY A 1 453 ? 147.844 112.349 100.525 1.00 100.51 ? 453 GLY B O   1 
ATOM   2935 N  N   . LEU A 1 454 ? 147.168 113.890 102.026 1.00 96.75  ? 454 LEU B N   1 
ATOM   2936 C  CA  . LEU A 1 454 ? 147.122 112.913 103.108 1.00 96.75  ? 454 LEU B CA  1 
ATOM   2937 C  C   . LEU A 1 454 ? 146.055 111.856 102.856 1.00 96.75  ? 454 LEU B C   1 
ATOM   2938 O  O   . LEU A 1 454 ? 146.265 110.671 103.143 1.00 96.75  ? 454 LEU B O   1 
ATOM   2939 C  CB  . LEU A 1 454 ? 146.889 113.615 104.445 1.00 96.75  ? 454 LEU B CB  1 
ATOM   2940 C  CG  . LEU A 1 454 ? 146.891 112.689 105.660 1.00 96.75  ? 454 LEU B CG  1 
ATOM   2941 C  CD1 . LEU A 1 454 ? 148.247 112.029 105.807 1.00 96.75  ? 454 LEU B CD1 1 
ATOM   2942 C  CD2 . LEU A 1 454 ? 146.549 113.462 106.916 1.00 96.75  ? 454 LEU B CD2 1 
ATOM   2943 N  N   . SER A 1 455 ? 144.903 112.263 102.315 1.00 97.02  ? 455 SER B N   1 
ATOM   2944 C  CA  . SER A 1 455 ? 143.846 111.299 102.028 1.00 97.02  ? 455 SER B CA  1 
ATOM   2945 C  C   . SER A 1 455 ? 144.315 110.242 101.039 1.00 97.02  ? 455 SER B C   1 
ATOM   2946 O  O   . SER A 1 455 ? 144.077 109.048 101.240 1.00 97.02  ? 455 SER B O   1 
ATOM   2947 C  CB  . SER A 1 455 ? 142.608 112.014 101.492 1.00 97.02  ? 455 SER B CB  1 
ATOM   2948 O  OG  . SER A 1 455 ? 141.980 112.771 102.506 1.00 97.02  ? 455 SER B OG  1 
ATOM   2949 N  N   . LYS A 1 456 ? 144.992 110.661 99.969  1.00 101.21 ? 456 LYS B N   1 
ATOM   2950 C  CA  . LYS A 1 456 ? 145.516 109.696 99.008  1.00 101.21 ? 456 LYS B CA  1 
ATOM   2951 C  C   . LYS A 1 456 ? 146.639 108.867 99.617  1.00 101.21 ? 456 LYS B C   1 
ATOM   2952 O  O   . LYS A 1 456 ? 146.776 107.675 99.314  1.00 101.21 ? 456 LYS B O   1 
ATOM   2953 C  CB  . LYS A 1 456 ? 145.997 110.418 97.751  1.00 101.21 ? 456 LYS B CB  1 
ATOM   2954 C  CG  . LYS A 1 456 ? 144.902 111.178 97.022  1.00 101.21 ? 456 LYS B CG  1 
ATOM   2955 C  CD  . LYS A 1 456 ? 145.458 111.951 95.837  1.00 101.21 ? 456 LYS B CD  1 
ATOM   2956 C  CE  . LYS A 1 456 ? 146.359 111.079 94.979  1.00 101.21 ? 456 LYS B CE  1 
ATOM   2957 N  NZ  . LYS A 1 456 ? 145.579 110.265 94.007  1.00 101.21 ? 456 LYS B NZ  1 
ATOM   2958 N  N   . TRP A 1 457 ? 147.456 109.482 100.477 1.00 103.11 ? 457 TRP B N   1 
ATOM   2959 C  CA  . TRP A 1 457 ? 148.533 108.749 101.132 1.00 103.11 ? 457 TRP B CA  1 
ATOM   2960 C  C   . TRP A 1 457 ? 147.988 107.649 102.034 1.00 103.11 ? 457 TRP B C   1 
ATOM   2961 O  O   . TRP A 1 457 ? 148.638 106.614 102.211 1.00 103.11 ? 457 TRP B O   1 
ATOM   2962 C  CB  . TRP A 1 457 ? 149.411 109.717 101.926 1.00 103.11 ? 457 TRP B CB  1 
ATOM   2963 C  CG  . TRP A 1 457 ? 150.790 109.204 102.227 1.00 103.11 ? 457 TRP B CG  1 
ATOM   2964 C  CD1 . TRP A 1 457 ? 151.118 108.017 102.812 1.00 103.11 ? 457 TRP B CD1 1 
ATOM   2965 C  CD2 . TRP A 1 457 ? 152.029 109.870 101.953 1.00 103.11 ? 457 TRP B CD2 1 
ATOM   2966 N  NE1 . TRP A 1 457 ? 152.482 107.901 102.920 1.00 103.11 ? 457 TRP B NE1 1 
ATOM   2967 C  CE2 . TRP A 1 457 ? 153.064 109.027 102.399 1.00 103.11 ? 457 TRP B CE2 1 
ATOM   2968 C  CE3 . TRP A 1 457 ? 152.362 111.098 101.373 1.00 103.11 ? 457 TRP B CE3 1 
ATOM   2969 C  CZ2 . TRP A 1 457 ? 154.409 109.371 102.284 1.00 103.11 ? 457 TRP B CZ2 1 
ATOM   2970 C  CZ3 . TRP A 1 457 ? 153.698 111.438 101.260 1.00 103.11 ? 457 TRP B CZ3 1 
ATOM   2971 C  CH2 . TRP A 1 457 ? 154.704 110.578 101.713 1.00 103.11 ? 457 TRP B CH2 1 
ATOM   2972 N  N   . ILE A 1 458 ? 146.805 107.850 102.612 1.00 101.34 ? 458 ILE B N   1 
ATOM   2973 C  CA  . ILE A 1 458 ? 146.191 106.787 103.404 1.00 101.34 ? 458 ILE B CA  1 
ATOM   2974 C  C   . ILE A 1 458 ? 145.464 105.793 102.506 1.00 101.34 ? 458 ILE B C   1 
ATOM   2975 O  O   . ILE A 1 458 ? 145.490 104.583 102.753 1.00 101.34 ? 458 ILE B O   1 
ATOM   2976 C  CB  . ILE A 1 458 ? 145.254 107.380 104.472 1.00 101.34 ? 458 ILE B CB  1 
ATOM   2977 C  CG1 . ILE A 1 458 ? 145.977 108.442 105.304 1.00 101.34 ? 458 ILE B CG1 1 
ATOM   2978 C  CG2 . ILE A 1 458 ? 144.709 106.285 105.374 1.00 101.34 ? 458 ILE B CG2 1 
ATOM   2979 C  CD1 . ILE A 1 458 ? 147.361 108.031 105.769 1.00 101.34 ? 458 ILE B CD1 1 
ATOM   2980 N  N   . GLY A 1 459 ? 144.812 106.279 101.450 1.00 106.77 ? 459 GLY B N   1 
ATOM   2981 C  CA  . GLY A 1 459 ? 144.024 105.423 100.586 1.00 106.77 ? 459 GLY B CA  1 
ATOM   2982 C  C   . GLY A 1 459 ? 144.808 104.528 99.655  1.00 106.77 ? 459 GLY B C   1 
ATOM   2983 O  O   . GLY A 1 459 ? 144.251 103.541 99.166  1.00 106.77 ? 459 GLY B O   1 
ATOM   2984 N  N   . ASN A 1 460 ? 146.076 104.843 99.380  1.00 109.07 ? 460 ASN B N   1 
ATOM   2985 C  CA  . ASN A 1 460 ? 146.861 103.955 98.528  1.00 109.07 ? 460 ASN B CA  1 
ATOM   2986 C  C   . ASN A 1 460 ? 147.174 102.639 99.232  1.00 109.07 ? 460 ASN B C   1 
ATOM   2987 O  O   . ASN A 1 460 ? 147.454 101.633 98.569  1.00 109.07 ? 460 ASN B O   1 
ATOM   2988 C  CB  . ASN A 1 460 ? 148.142 104.651 98.056  1.00 109.07 ? 460 ASN B CB  1 
ATOM   2989 C  CG  . ASN A 1 460 ? 149.105 104.948 99.186  1.00 109.07 ? 460 ASN B CG  1 
ATOM   2990 O  OD1 . ASN A 1 460 ? 148.822 104.680 100.348 1.00 109.07 ? 460 ASN B OD1 1 
ATOM   2991 N  ND2 . ASN A 1 460 ? 150.261 105.505 98.842  1.00 109.07 ? 460 ASN B ND2 1 
ATOM   2992 N  N   . LYS A 1 461 ? 147.135 102.622 100.569 1.00 109.98 ? 461 LYS B N   1 
ATOM   2993 C  CA  . LYS A 1 461 ? 147.204 101.359 101.296 1.00 109.98 ? 461 LYS B CA  1 
ATOM   2994 C  C   . LYS A 1 461 ? 145.990 100.478 101.037 1.00 109.98 ? 461 LYS B C   1 
ATOM   2995 O  O   . LYS A 1 461 ? 146.071 99.260  101.227 1.00 109.98 ? 461 LYS B O   1 
ATOM   2996 C  CB  . LYS A 1 461 ? 147.339 101.599 102.802 1.00 109.98 ? 461 LYS B CB  1 
ATOM   2997 C  CG  . LYS A 1 461 ? 148.764 101.803 103.305 1.00 109.98 ? 461 LYS B CG  1 
ATOM   2998 C  CD  . LYS A 1 461 ? 149.310 103.174 102.965 1.00 109.98 ? 461 LYS B CD  1 
ATOM   2999 C  CE  . LYS A 1 461 ? 150.694 103.378 103.558 1.00 109.98 ? 461 LYS B CE  1 
ATOM   3000 N  NZ  . LYS A 1 461 ? 151.296 104.673 103.138 1.00 109.98 ? 461 LYS B NZ  1 
ATOM   3001 N  N   . LEU A 1 462 ? 144.865 101.064 100.622 1.00 111.15 ? 462 LEU B N   1 
ATOM   3002 C  CA  . LEU A 1 462 ? 143.685 100.269 100.306 1.00 111.15 ? 462 LEU B CA  1 
ATOM   3003 C  C   . LEU A 1 462 ? 143.841 99.504  98.999  1.00 111.15 ? 462 LEU B C   1 
ATOM   3004 O  O   . LEU A 1 462 ? 143.103 98.541  98.769  1.00 111.15 ? 462 LEU B O   1 
ATOM   3005 C  CB  . LEU A 1 462 ? 142.447 101.170 100.247 1.00 111.15 ? 462 LEU B CB  1 
ATOM   3006 C  CG  . LEU A 1 462 ? 141.069 100.511 100.152 1.00 111.15 ? 462 LEU B CG  1 
ATOM   3007 C  CD1 . LEU A 1 462 ? 140.804 99.641  101.368 1.00 111.15 ? 462 LEU B CD1 1 
ATOM   3008 C  CD2 . LEU A 1 462 ? 139.981 101.561 99.993  1.00 111.15 ? 462 LEU B CD2 1 
ATOM   3009 N  N   . SER A 1 463 ? 144.779 99.907  98.140  1.00 111.77 ? 463 SER B N   1 
ATOM   3010 C  CA  . SER A 1 463 ? 144.971 99.200  96.875  1.00 111.77 ? 463 SER B CA  1 
ATOM   3011 C  C   . SER A 1 463 ? 145.394 97.749  97.072  1.00 111.77 ? 463 SER B C   1 
ATOM   3012 O  O   . SER A 1 463 ? 144.795 96.867  96.432  1.00 111.77 ? 463 SER B O   1 
ATOM   3013 C  CB  . SER A 1 463 ? 145.964 99.971  95.998  1.00 111.77 ? 463 SER B CB  1 
ATOM   3014 O  OG  . SER A 1 463 ? 145.357 101.115 95.425  1.00 111.77 ? 463 SER B OG  1 
ATOM   3015 N  N   . PRO A 1 464 ? 146.393 97.420  97.904  1.00 112.96 ? 464 PRO B N   1 
ATOM   3016 C  CA  . PRO A 1 464 ? 146.637 95.997  98.195  1.00 112.96 ? 464 PRO B CA  1 
ATOM   3017 C  C   . PRO A 1 464 ? 145.454 95.315  98.854  1.00 112.96 ? 464 PRO B C   1 
ATOM   3018 O  O   . PRO A 1 464 ? 145.225 94.121  98.622  1.00 112.96 ? 464 PRO B O   1 
ATOM   3019 C  CB  . PRO A 1 464 ? 147.860 96.030  99.122  1.00 112.96 ? 464 PRO B CB  1 
ATOM   3020 C  CG  . PRO A 1 464 ? 148.520 97.328  98.837  1.00 112.96 ? 464 PRO B CG  1 
ATOM   3021 C  CD  . PRO A 1 464 ? 147.409 98.281  98.537  1.00 112.96 ? 464 PRO B CD  1 
ATOM   3022 N  N   . LEU A 1 465 ? 144.696 96.039  99.671  1.00 108.71 ? 465 LEU B N   1 
ATOM   3023 C  CA  . LEU A 1 465 ? 143.509 95.507  100.320 1.00 108.71 ? 465 LEU B CA  1 
ATOM   3024 C  C   . LEU A 1 465 ? 142.307 95.677  99.391  1.00 108.71 ? 465 LEU B C   1 
ATOM   3025 O  O   . LEU A 1 465 ? 142.449 95.938  98.193  1.00 108.71 ? 465 LEU B O   1 
ATOM   3026 C  CB  . LEU A 1 465 ? 143.291 96.184  101.672 1.00 108.71 ? 465 LEU B CB  1 
ATOM   3027 C  CG  . LEU A 1 465 ? 143.980 95.567  102.893 1.00 108.71 ? 465 LEU B CG  1 
ATOM   3028 C  CD1 . LEU A 1 465 ? 143.500 94.141  103.116 1.00 108.71 ? 465 LEU B CD1 1 
ATOM   3029 C  CD2 . LEU A 1 465 ? 145.497 95.616  102.772 1.00 108.71 ? 465 LEU B CD2 1 
ATOM   3030 N  N   . GLY A 1 466 ? 141.103 95.509  99.933  1.00 101.36 ? 466 GLY B N   1 
ATOM   3031 C  CA  . GLY A 1 466 ? 139.887 95.628  99.166  1.00 101.36 ? 466 GLY B CA  1 
ATOM   3032 C  C   . GLY A 1 466 ? 139.347 94.320  98.633  1.00 101.36 ? 466 GLY B C   1 
ATOM   3033 O  O   . GLY A 1 466 ? 138.163 94.250  98.285  1.00 101.36 ? 466 GLY B O   1 
ATOM   3034 N  N   . SER A 1 467 ? 140.179 93.282  98.559  1.00 98.04  ? 467 SER B N   1 
ATOM   3035 C  CA  . SER A 1 467 ? 139.708 91.950  98.213  1.00 98.04  ? 467 SER B CA  1 
ATOM   3036 C  C   . SER A 1 467 ? 139.036 91.252  99.385  1.00 98.04  ? 467 SER B C   1 
ATOM   3037 O  O   . SER A 1 467 ? 138.390 90.218  99.184  1.00 98.04  ? 467 SER B O   1 
ATOM   3038 C  CB  . SER A 1 467 ? 140.871 91.096  97.703  1.00 98.04  ? 467 SER B CB  1 
ATOM   3039 O  OG  . SER A 1 467 ? 141.994 91.205  98.560  1.00 98.04  ? 467 SER B OG  1 
ATOM   3040 N  N   . LEU A 1 468 ? 139.179 91.788  100.592 1.00 87.06  ? 468 LEU B N   1 
ATOM   3041 C  CA  . LEU A 1 468 ? 138.523 91.210  101.751 1.00 87.06  ? 468 LEU B CA  1 
ATOM   3042 C  C   . LEU A 1 468 ? 137.009 91.371  101.626 1.00 87.06  ? 468 LEU B C   1 
ATOM   3043 O  O   . LEU A 1 468 ? 136.531 92.412  101.164 1.00 87.06  ? 468 LEU B O   1 
ATOM   3044 C  CB  . LEU A 1 468 ? 139.018 91.886  103.028 1.00 87.06  ? 468 LEU B CB  1 
ATOM   3045 C  CG  . LEU A 1 468 ? 140.473 91.615  103.419 1.00 87.06  ? 468 LEU B CG  1 
ATOM   3046 C  CD1 . LEU A 1 468 ? 140.687 91.840  104.908 1.00 87.06  ? 468 LEU B CD1 1 
ATOM   3047 C  CD2 . LEU A 1 468 ? 140.890 90.206  103.023 1.00 87.06  ? 468 LEU B CD2 1 
ATOM   3048 N  N   . PRO A 1 469 ? 136.233 90.367  102.020 1.00 79.36  ? 469 PRO B N   1 
ATOM   3049 C  CA  . PRO A 1 469 ? 134.775 90.486  101.938 1.00 79.36  ? 469 PRO B CA  1 
ATOM   3050 C  C   . PRO A 1 469 ? 134.242 91.495  102.944 1.00 79.36  ? 469 PRO B C   1 
ATOM   3051 O  O   . PRO A 1 469 ? 134.912 91.873  103.907 1.00 79.36  ? 469 PRO B O   1 
ATOM   3052 C  CB  . PRO A 1 469 ? 134.281 89.071  102.251 1.00 79.36  ? 469 PRO B CB  1 
ATOM   3053 C  CG  . PRO A 1 469 ? 135.381 88.458  103.047 1.00 79.36  ? 469 PRO B CG  1 
ATOM   3054 C  CD  . PRO A 1 469 ? 136.657 89.051  102.527 1.00 79.36  ? 469 PRO B CD  1 
ATOM   3055 N  N   . ALA A 1 470 ? 133.007 91.936  102.696 1.00 74.16  ? 470 ALA B N   1 
ATOM   3056 C  CA  . ALA A 1 470 ? 132.409 92.979  103.525 1.00 74.16  ? 470 ALA B CA  1 
ATOM   3057 C  C   . ALA A 1 470 ? 132.258 92.527  104.972 1.00 74.16  ? 470 ALA B C   1 
ATOM   3058 O  O   . ALA A 1 470 ? 132.534 93.296  105.900 1.00 74.16  ? 470 ALA B O   1 
ATOM   3059 C  CB  . ALA A 1 470 ? 131.056 93.395  102.949 1.00 74.16  ? 470 ALA B CB  1 
ATOM   3060 N  N   . TRP A 1 471 ? 131.822 91.283  105.187 1.00 73.75  ? 471 TRP B N   1 
ATOM   3061 C  CA  . TRP A 1 471 ? 131.636 90.793  106.550 1.00 73.75  ? 471 TRP B CA  1 
ATOM   3062 C  C   . TRP A 1 471 ? 132.956 90.765  107.309 1.00 73.75  ? 471 TRP B C   1 
ATOM   3063 O  O   . TRP A 1 471 ? 133.000 91.063  108.508 1.00 73.75  ? 471 TRP B O   1 
ATOM   3064 C  CB  . TRP A 1 471 ? 130.995 89.405  106.531 1.00 73.75  ? 471 TRP B CB  1 
ATOM   3065 C  CG  . TRP A 1 471 ? 131.798 88.372  105.804 1.00 73.75  ? 471 TRP B CG  1 
ATOM   3066 C  CD1 . TRP A 1 471 ? 131.692 88.030  104.489 1.00 73.75  ? 471 TRP B CD1 1 
ATOM   3067 C  CD2 . TRP A 1 471 ? 132.829 87.541  106.352 1.00 73.75  ? 471 TRP B CD2 1 
ATOM   3068 N  NE1 . TRP A 1 471 ? 132.592 87.040  104.183 1.00 73.75  ? 471 TRP B NE1 1 
ATOM   3069 C  CE2 . TRP A 1 471 ? 133.303 86.723  105.309 1.00 73.75  ? 471 TRP B CE2 1 
ATOM   3070 C  CE3 . TRP A 1 471 ? 133.397 87.411  107.622 1.00 73.75  ? 471 TRP B CE3 1 
ATOM   3071 C  CZ2 . TRP A 1 471 ? 134.318 85.789  105.497 1.00 73.75  ? 471 TRP B CZ2 1 
ATOM   3072 C  CZ3 . TRP A 1 471 ? 134.405 86.483  107.806 1.00 73.75  ? 471 TRP B CZ3 1 
ATOM   3073 C  CH2 . TRP A 1 471 ? 134.855 85.684  106.750 1.00 73.75  ? 471 TRP B CH2 1 
ATOM   3074 N  N   . LEU A 1 472 ? 134.044 90.413  106.627 1.00 70.30  ? 472 LEU B N   1 
ATOM   3075 C  CA  . LEU A 1 472 ? 135.345 90.406  107.283 1.00 70.30  ? 472 LEU B CA  1 
ATOM   3076 C  C   . LEU A 1 472 ? 135.751 91.816  107.699 1.00 70.30  ? 472 LEU B C   1 
ATOM   3077 O  O   . LEU A 1 472 ? 136.253 92.023  108.811 1.00 70.30  ? 472 LEU B O   1 
ATOM   3078 C  CB  . LEU A 1 472 ? 136.384 89.782  106.355 1.00 70.30  ? 472 LEU B CB  1 
ATOM   3079 C  CG  . LEU A 1 472 ? 137.814 89.645  106.867 1.00 70.30  ? 472 LEU B CG  1 
ATOM   3080 C  CD1 . LEU A 1 472 ? 137.823 88.812  108.136 1.00 70.30  ? 472 LEU B CD1 1 
ATOM   3081 C  CD2 . LEU A 1 472 ? 138.680 89.001  105.806 1.00 70.30  ? 472 LEU B CD2 1 
ATOM   3082 N  N   . ILE A 1 473 ? 135.527 92.798  106.822 1.00 65.33  ? 473 ILE B N   1 
ATOM   3083 C  CA  . ILE A 1 473 ? 135.813 94.187  107.167 1.00 65.33  ? 473 ILE B CA  1 
ATOM   3084 C  C   . ILE A 1 473 ? 134.983 94.612  108.368 1.00 65.33  ? 473 ILE B C   1 
ATOM   3085 O  O   . ILE A 1 473 ? 135.469 95.320  109.259 1.00 65.33  ? 473 ILE B O   1 
ATOM   3086 C  CB  . ILE A 1 473 ? 135.565 95.101  105.954 1.00 65.33  ? 473 ILE B CB  1 
ATOM   3087 C  CG1 . ILE A 1 473 ? 136.415 94.652  104.765 1.00 65.33  ? 473 ILE B CG1 1 
ATOM   3088 C  CG2 . ILE A 1 473 ? 135.857 96.547  106.309 1.00 65.33  ? 473 ILE B CG2 1 
ATOM   3089 C  CD1 . ILE A 1 473 ? 137.890 94.929  104.928 1.00 65.33  ? 473 ILE B CD1 1 
ATOM   3090 N  N   . ILE A 1 474 ? 133.721 94.180  108.415 1.00 62.93  ? 474 ILE B N   1 
ATOM   3091 C  CA  . ILE A 1 474 ? 132.885 94.425  109.587 1.00 62.93  ? 474 ILE B CA  1 
ATOM   3092 C  C   . ILE A 1 474 ? 133.536 93.845  110.832 1.00 62.93  ? 474 ILE B C   1 
ATOM   3093 O  O   . ILE A 1 474 ? 133.562 94.479  111.894 1.00 62.93  ? 474 ILE B O   1 
ATOM   3094 C  CB  . ILE A 1 474 ? 131.479 93.837  109.374 1.00 62.93  ? 474 ILE B CB  1 
ATOM   3095 C  CG1 . ILE A 1 474 ? 130.788 94.523  108.203 1.00 62.93  ? 474 ILE B CG1 1 
ATOM   3096 C  CG2 . ILE A 1 474 ? 130.647 93.966  110.639 1.00 62.93  ? 474 ILE B CG2 1 
ATOM   3097 C  CD1 . ILE A 1 474 ? 130.295 95.883  108.546 1.00 62.93  ? 474 ILE B CD1 1 
ATOM   3098 N  N   . LEU A 1 475 ? 134.062 92.625  110.722 1.00 62.07  ? 475 LEU B N   1 
ATOM   3099 C  CA  . LEU A 1 475 ? 134.639 91.955  111.882 1.00 62.07  ? 475 LEU B CA  1 
ATOM   3100 C  C   . LEU A 1 475 ? 135.837 92.728  112.424 1.00 62.07  ? 475 LEU B C   1 
ATOM   3101 O  O   . LEU A 1 475 ? 135.901 93.035  113.622 1.00 62.07  ? 475 LEU B O   1 
ATOM   3102 C  CB  . LEU A 1 475 ? 135.034 90.526  111.509 1.00 62.07  ? 475 LEU B CB  1 
ATOM   3103 C  CG  . LEU A 1 475 ? 135.596 89.645  112.623 1.00 62.07  ? 475 LEU B CG  1 
ATOM   3104 C  CD1 . LEU A 1 475 ? 134.550 89.442  113.703 1.00 62.07  ? 475 LEU B CD1 1 
ATOM   3105 C  CD2 . LEU A 1 475 ? 136.057 88.309  112.065 1.00 62.07  ? 475 LEU B CD2 1 
ATOM   3106 N  N   . ILE A 1 476 ? 136.795 93.064  111.553 1.00 61.12  ? 476 ILE B N   1 
ATOM   3107 C  CA  . ILE A 1 476 ? 137.953 93.832  112.022 1.00 61.12  ? 476 ILE B CA  1 
ATOM   3108 C  C   . ILE A 1 476 ? 137.533 95.199  112.550 1.00 61.12  ? 476 ILE B C   1 
ATOM   3109 O  O   . ILE A 1 476 ? 138.051 95.657  113.574 1.00 61.12  ? 476 ILE B O   1 
ATOM   3110 C  CB  . ILE A 1 476 ? 139.063 93.954  110.956 1.00 61.12  ? 476 ILE B CB  1 
ATOM   3111 C  CG1 . ILE A 1 476 ? 139.676 92.597  110.590 1.00 61.12  ? 476 ILE B CG1 1 
ATOM   3112 C  CG2 . ILE A 1 476 ? 140.156 94.905  111.419 1.00 61.12  ? 476 ILE B CG2 1 
ATOM   3113 C  CD1 . ILE A 1 476 ? 139.036 91.857  109.501 1.00 61.12  ? 476 ILE B CD1 1 
ATOM   3114 N  N   . SER A 1 477 ? 136.605 95.880  111.874 1.00 60.20  ? 477 SER B N   1 
ATOM   3115 C  CA  . SER A 1 477 ? 136.198 97.202  112.342 1.00 60.20  ? 477 SER B CA  1 
ATOM   3116 C  C   . SER A 1 477 ? 135.593 97.129  113.739 1.00 60.20  ? 477 SER B C   1 
ATOM   3117 O  O   . SER A 1 477 ? 135.943 97.922  114.622 1.00 60.20  ? 477 SER B O   1 
ATOM   3118 C  CB  . SER A 1 477 ? 135.207 97.823  111.359 1.00 60.20  ? 477 SER B CB  1 
ATOM   3119 O  OG  . SER A 1 477 ? 133.927 97.231  111.490 1.00 60.20  ? 477 SER B OG  1 
ATOM   3120 N  N   . SER A 1 478 ? 134.696 96.167  113.962 1.00 57.35  ? 478 SER B N   1 
ATOM   3121 C  CA  . SER A 1 478 ? 134.046 96.041  115.262 1.00 57.35  ? 478 SER B CA  1 
ATOM   3122 C  C   . SER A 1 478 ? 135.048 95.670  116.346 1.00 57.35  ? 478 SER B C   1 
ATOM   3123 O  O   . SER A 1 478 ? 135.009 96.218  117.455 1.00 57.35  ? 478 SER B O   1 
ATOM   3124 C  CB  . SER A 1 478 ? 132.923 95.009  115.187 1.00 57.35  ? 478 SER B CB  1 
ATOM   3125 O  OG  . SER A 1 478 ? 131.936 95.398  114.250 1.00 57.35  ? 478 SER B OG  1 
ATOM   3126 N  N   . LEU A 1 479 ? 135.956 94.734  116.050 1.00 56.82  ? 479 LEU B N   1 
ATOM   3127 C  CA  . LEU A 1 479 ? 136.957 94.358  117.045 1.00 56.82  ? 479 LEU B CA  1 
ATOM   3128 C  C   . LEU A 1 479 ? 137.883 95.521  117.376 1.00 56.82  ? 479 LEU B C   1 
ATOM   3129 O  O   . LEU A 1 479 ? 138.214 95.738  118.546 1.00 56.82  ? 479 LEU B O   1 
ATOM   3130 C  CB  . LEU A 1 479 ? 137.755 93.140  116.580 1.00 56.82  ? 479 LEU B CB  1 
ATOM   3131 C  CG  . LEU A 1 479 ? 137.174 91.756  116.891 1.00 56.82  ? 479 LEU B CG  1 
ATOM   3132 C  CD1 . LEU A 1 479 ? 137.142 91.552  118.394 1.00 56.82  ? 479 LEU B CD1 1 
ATOM   3133 C  CD2 . LEU A 1 479 ? 135.785 91.563  116.324 1.00 56.82  ? 479 LEU B CD2 1 
ATOM   3134 N  N   . MET A 1 480 ? 138.309 96.287  116.369 1.00 58.15  ? 480 MET B N   1 
ATOM   3135 C  CA  . MET A 1 480 ? 139.170 97.434  116.640 1.00 58.15  ? 480 MET B CA  1 
ATOM   3136 C  C   . MET A 1 480 ? 138.449 98.482  117.477 1.00 58.15  ? 480 MET B C   1 
ATOM   3137 O  O   . MET A 1 480 ? 139.030 99.040  118.417 1.00 58.15  ? 480 MET B O   1 
ATOM   3138 C  CB  . MET A 1 480 ? 139.674 98.045  115.334 1.00 58.15  ? 480 MET B CB  1 
ATOM   3139 C  CG  . MET A 1 480 ? 140.655 97.168  114.576 1.00 58.15  ? 480 MET B CG  1 
ATOM   3140 S  SD  . MET A 1 480 ? 141.561 98.063  113.299 1.00 58.15  ? 480 MET B SD  1 
ATOM   3141 C  CE  . MET A 1 480 ? 140.341 99.269  112.789 1.00 58.15  ? 480 MET B CE  1 
ATOM   3142 N  N   . VAL A 1 481 ? 137.183 98.760  117.160 1.00 52.12  ? 481 VAL B N   1 
ATOM   3143 C  CA  . VAL A 1 481 ? 136.441 99.755  117.929 1.00 52.12  ? 481 VAL B CA  1 
ATOM   3144 C  C   . VAL A 1 481 ? 136.263 99.298  119.372 1.00 52.12  ? 481 VAL B C   1 
ATOM   3145 O  O   . VAL A 1 481 ? 136.475 100.074 120.314 1.00 52.12  ? 481 VAL B O   1 
ATOM   3146 C  CB  . VAL A 1 481 ? 135.088 100.051 117.260 1.00 52.12  ? 481 VAL B CB  1 
ATOM   3147 C  CG1 . VAL A 1 481 ? 134.245 100.918 118.161 1.00 52.12  ? 481 VAL B CG1 1 
ATOM   3148 C  CG2 . VAL A 1 481 ? 135.297 100.735 115.928 1.00 52.12  ? 481 VAL B CG2 1 
ATOM   3149 N  N   . THR A 1 482 ? 135.875 98.034  119.572 1.00 53.51  ? 482 THR B N   1 
ATOM   3150 C  CA  . THR A 1 482 ? 135.689 97.528  120.928 1.00 53.51  ? 482 THR B CA  1 
ATOM   3151 C  C   . THR A 1 482 ? 136.998 97.529  121.702 1.00 53.51  ? 482 THR B C   1 
ATOM   3152 O  O   . THR A 1 482 ? 137.021 97.862  122.891 1.00 53.51  ? 482 THR B O   1 
ATOM   3153 C  CB  . THR A 1 482 ? 135.095 96.122  120.899 1.00 53.51  ? 482 THR B CB  1 
ATOM   3154 O  OG1 . THR A 1 482 ? 135.780 95.332  119.922 1.00 53.51  ? 482 THR B OG1 1 
ATOM   3155 C  CG2 . THR A 1 482 ? 133.620 96.173  120.561 1.00 53.51  ? 482 THR B CG2 1 
ATOM   3156 N  N   . SER A 1 483 ? 138.099 97.149  121.051 1.00 54.63  ? 483 SER B N   1 
ATOM   3157 C  CA  . SER A 1 483 ? 139.387 97.143  121.733 1.00 54.63  ? 483 SER B CA  1 
ATOM   3158 C  C   . SER A 1 483 ? 139.819 98.550  122.120 1.00 54.63  ? 483 SER B C   1 
ATOM   3159 O  O   . SER A 1 483 ? 140.336 98.762  123.222 1.00 54.63  ? 483 SER B O   1 
ATOM   3160 C  CB  . SER A 1 483 ? 140.442 96.477  120.853 1.00 54.63  ? 483 SER B CB  1 
ATOM   3161 O  OG  . SER A 1 483 ? 140.129 95.112  120.644 1.00 54.63  ? 483 SER B OG  1 
ATOM   3162 N  N   . LEU A 1 484 ? 139.619 99.528  121.234 1.00 51.44  ? 484 LEU B N   1 
ATOM   3163 C  CA  . LEU A 1 484 ? 140.065 100.879 121.553 1.00 51.44  ? 484 LEU B CA  1 
ATOM   3164 C  C   . LEU A 1 484 ? 139.202 101.507 122.639 1.00 51.44  ? 484 LEU B C   1 
ATOM   3165 O  O   . LEU A 1 484 ? 139.718 102.206 123.519 1.00 51.44  ? 484 LEU B O   1 
ATOM   3166 C  CB  . LEU A 1 484 ? 140.070 101.759 120.306 1.00 51.44  ? 484 LEU B CB  1 
ATOM   3167 C  CG  . LEU A 1 484 ? 140.650 103.141 120.618 1.00 51.44  ? 484 LEU B CG  1 
ATOM   3168 C  CD1 . LEU A 1 484 ? 142.020 103.005 121.276 1.00 51.44  ? 484 LEU B CD1 1 
ATOM   3169 C  CD2 . LEU A 1 484 ? 140.731 104.022 119.394 1.00 51.44  ? 484 LEU B CD2 1 
ATOM   3170 N  N   . THR A 1 485 ? 137.889 101.266 122.608 1.00 50.30  ? 485 THR B N   1 
ATOM   3171 C  CA  . THR A 1 485 ? 137.022 101.930 123.574 1.00 50.30  ? 485 THR B CA  1 
ATOM   3172 C  C   . THR A 1 485 ? 137.211 101.417 124.994 1.00 50.30  ? 485 THR B C   1 
ATOM   3173 O  O   . THR A 1 485 ? 136.659 102.015 125.923 1.00 50.30  ? 485 THR B O   1 
ATOM   3174 C  CB  . THR A 1 485 ? 135.555 101.788 123.170 1.00 50.30  ? 485 THR B CB  1 
ATOM   3175 O  OG1 . THR A 1 485 ? 134.748 102.597 124.034 1.00 50.30  ? 485 THR B OG1 1 
ATOM   3176 C  CG2 . THR A 1 485 ? 135.105 100.349 123.286 1.00 50.30  ? 485 THR B CG2 1 
ATOM   3177 N  N   . GLU A 1 486 ? 137.968 100.333 125.189 1.00 53.91  ? 486 GLU B N   1 
ATOM   3178 C  CA  . GLU A 1 486 ? 138.248 99.864  126.542 1.00 53.91  ? 486 GLU B CA  1 
ATOM   3179 C  C   . GLU A 1 486 ? 139.126 100.844 127.307 1.00 53.91  ? 486 GLU B C   1 
ATOM   3180 O  O   . GLU A 1 486 ? 138.989 100.971 128.528 1.00 53.91  ? 486 GLU B O   1 
ATOM   3181 C  CB  . GLU A 1 486 ? 138.922 98.490  126.504 1.00 53.91  ? 486 GLU B CB  1 
ATOM   3182 C  CG  . GLU A 1 486 ? 138.194 97.418  125.702 1.00 53.91  ? 486 GLU B CG  1 
ATOM   3183 C  CD  . GLU A 1 486 ? 136.843 97.007  126.272 1.00 53.91  ? 486 GLU B CD  1 
ATOM   3184 O  OE1 . GLU A 1 486 ? 136.307 97.691  127.167 1.00 53.91  ? 486 GLU B OE1 1 
ATOM   3185 O  OE2 . GLU A 1 486 ? 136.301 95.987  125.799 1.00 53.91  ? 486 GLU B OE2 1 
ATOM   3186 N  N   . VAL A 1 487 ? 140.031 101.535 126.617 1.00 51.47  ? 487 VAL B N   1 
ATOM   3187 C  CA  . VAL A 1 487 ? 140.990 102.429 127.250 1.00 51.47  ? 487 VAL B CA  1 
ATOM   3188 C  C   . VAL A 1 487 ? 140.801 103.873 126.806 1.00 51.47  ? 487 VAL B C   1 
ATOM   3189 O  O   . VAL A 1 487 ? 141.639 104.726 127.113 1.00 51.47  ? 487 VAL B O   1 
ATOM   3190 C  CB  . VAL A 1 487 ? 142.432 101.965 126.993 1.00 51.47  ? 487 VAL B CB  1 
ATOM   3191 C  CG1 . VAL A 1 487 ? 142.633 100.554 127.516 1.00 51.47  ? 487 VAL B CG1 1 
ATOM   3192 C  CG2 . VAL A 1 487 ? 142.752 102.035 125.510 1.00 51.47  ? 487 VAL B CG2 1 
ATOM   3193 N  N   . ALA A 1 488 ? 139.721 104.173 126.089 1.00 51.25  ? 488 ALA B N   1 
ATOM   3194 C  CA  . ALA A 1 488 ? 139.460 105.527 125.626 1.00 51.25  ? 488 ALA B CA  1 
ATOM   3195 C  C   . ALA A 1 488 ? 137.986 105.849 125.818 1.00 51.25  ? 488 ALA B C   1 
ATOM   3196 O  O   . ALA A 1 488 ? 137.138 104.958 125.889 1.00 51.25  ? 488 ALA B O   1 
ATOM   3197 C  CB  . ALA A 1 488 ? 139.857 105.710 124.157 1.00 51.25  ? 488 ALA B CB  1 
ATOM   3198 N  N   . SER A 1 489 ? 137.692 107.142 125.908 1.00 52.42  ? 489 SER B N   1 
ATOM   3199 C  CA  . SER A 1 489 ? 136.312 107.583 126.041 1.00 52.42  ? 489 SER B CA  1 
ATOM   3200 C  C   . SER A 1 489 ? 135.535 107.282 124.766 1.00 52.42  ? 489 SER B C   1 
ATOM   3201 O  O   . SER A 1 489 ? 136.064 107.391 123.657 1.00 52.42  ? 489 SER B O   1 
ATOM   3202 C  CB  . SER A 1 489 ? 136.262 109.077 126.357 1.00 52.42  ? 489 SER B CB  1 
ATOM   3203 O  OG  . SER A 1 489 ? 136.845 109.835 125.314 1.00 52.42  ? 489 SER B OG  1 
ATOM   3204 N  N   . ASN A 1 490 ? 134.272 106.890 124.933 1.00 50.69  ? 490 ASN B N   1 
ATOM   3205 C  CA  . ASN A 1 490 ? 133.458 106.482 123.789 1.00 50.69  ? 490 ASN B CA  1 
ATOM   3206 C  C   . ASN A 1 490 ? 133.259 107.590 122.760 1.00 50.69  ? 490 ASN B C   1 
ATOM   3207 O  O   . ASN A 1 490 ? 133.406 107.312 121.555 1.00 50.69  ? 490 ASN B O   1 
ATOM   3208 C  CB  . ASN A 1 490 ? 132.115 105.939 124.288 1.00 50.69  ? 490 ASN B CB  1 
ATOM   3209 C  CG  . ASN A 1 490 ? 132.279 104.805 125.274 1.00 50.69  ? 490 ASN B CG  1 
ATOM   3210 O  OD1 . ASN A 1 490 ? 133.182 103.980 125.143 1.00 50.69  ? 490 ASN B OD1 1 
ATOM   3211 N  ND2 . ASN A 1 490 ? 131.404 104.756 126.271 1.00 50.69  ? 490 ASN B ND2 1 
ATOM   3212 N  N   . PRO A 1 491 ? 132.904 108.829 123.132 1.00 51.97  ? 491 PRO B N   1 
ATOM   3213 C  CA  . PRO A 1 491 ? 132.768 109.870 122.098 1.00 51.97  ? 491 PRO B CA  1 
ATOM   3214 C  C   . PRO A 1 491 ? 134.040 110.099 121.302 1.00 51.97  ? 491 PRO B C   1 
ATOM   3215 O  O   . PRO A 1 491 ? 133.974 110.290 120.081 1.00 51.97  ? 491 PRO B O   1 
ATOM   3216 C  CB  . PRO A 1 491 ? 132.364 111.116 122.901 1.00 51.97  ? 491 PRO B CB  1 
ATOM   3217 C  CG  . PRO A 1 491 ? 132.681 110.802 124.317 1.00 51.97  ? 491 PRO B CG  1 
ATOM   3218 C  CD  . PRO A 1 491 ? 132.509 109.334 124.457 1.00 51.97  ? 491 PRO B CD  1 
ATOM   3219 N  N   . ALA A 1 492 ? 135.203 110.065 121.955 1.00 49.89  ? 492 ALA B N   1 
ATOM   3220 C  CA  . ALA A 1 492 ? 136.455 110.231 121.227 1.00 49.89  ? 492 ALA B CA  1 
ATOM   3221 C  C   . ALA A 1 492 ? 136.663 109.101 120.228 1.00 49.89  ? 492 ALA B C   1 
ATOM   3222 O  O   . ALA A 1 492 ? 137.040 109.343 119.077 1.00 49.89  ? 492 ALA B O   1 
ATOM   3223 C  CB  . ALA A 1 492 ? 137.626 110.306 122.203 1.00 49.89  ? 492 ALA B CB  1 
ATOM   3224 N  N   . THR A 1 493 ? 136.403 107.861 120.644 1.00 49.59  ? 493 THR B N   1 
ATOM   3225 C  CA  . THR A 1 493 ? 136.589 106.727 119.746 1.00 49.59  ? 493 THR B CA  1 
ATOM   3226 C  C   . THR A 1 493 ? 135.660 106.814 118.542 1.00 49.59  ? 493 THR B C   1 
ATOM   3227 O  O   . THR A 1 493 ? 136.083 106.581 117.400 1.00 49.59  ? 493 THR B O   1 
ATOM   3228 C  CB  . THR A 1 493 ? 136.360 105.419 120.500 1.00 49.59  ? 493 THR B CB  1 
ATOM   3229 O  OG1 . THR A 1 493 ? 137.252 105.352 121.618 1.00 49.59  ? 493 THR B OG1 1 
ATOM   3230 C  CG2 . THR A 1 493 ? 136.607 104.232 119.590 1.00 49.59  ? 493 THR B CG2 1 
ATOM   3231 N  N   . ILE A 1 494 ? 134.390 107.151 118.774 1.00 50.62  ? 494 ILE B N   1 
ATOM   3232 C  CA  . ILE A 1 494 ? 133.451 107.190 117.660 1.00 50.62  ? 494 ILE B CA  1 
ATOM   3233 C  C   . ILE A 1 494 ? 133.783 108.342 116.719 1.00 50.62  ? 494 ILE B C   1 
ATOM   3234 O  O   . ILE A 1 494 ? 133.756 108.179 115.494 1.00 50.62  ? 494 ILE B O   1 
ATOM   3235 C  CB  . ILE A 1 494 ? 131.994 107.243 118.161 1.00 50.62  ? 494 ILE B CB  1 
ATOM   3236 C  CG1 . ILE A 1 494 ? 131.029 107.057 116.992 1.00 50.62  ? 494 ILE B CG1 1 
ATOM   3237 C  CG2 . ILE A 1 494 ? 131.694 108.532 118.895 1.00 50.62  ? 494 ILE B CG2 1 
ATOM   3238 C  CD1 . ILE A 1 494 ? 131.179 105.728 116.292 1.00 50.62  ? 494 ILE B CD1 1 
ATOM   3239 N  N   . THR A 1 495 ? 134.142 109.512 117.260 1.00 48.11  ? 495 THR B N   1 
ATOM   3240 C  CA  . THR A 1 495 ? 134.490 110.627 116.389 1.00 48.11  ? 495 THR B CA  1 
ATOM   3241 C  C   . THR A 1 495 ? 135.839 110.428 115.714 1.00 48.11  ? 495 THR B C   1 
ATOM   3242 O  O   . THR A 1 495 ? 136.141 111.128 114.743 1.00 48.11  ? 495 THR B O   1 
ATOM   3243 C  CB  . THR A 1 495 ? 134.491 111.939 117.171 1.00 48.11  ? 495 THR B CB  1 
ATOM   3244 O  OG1 . THR A 1 495 ? 134.408 113.038 116.256 1.00 48.11  ? 495 THR B OG1 1 
ATOM   3245 C  CG2 . THR A 1 495 ? 135.758 112.074 117.985 1.00 48.11  ? 495 THR B CG2 1 
ATOM   3246 N  N   . LEU A 1 496 ? 136.656 109.497 116.206 1.00 49.02  ? 496 LEU B N   1 
ATOM   3247 C  CA  . LEU A 1 496 ? 137.931 109.225 115.557 1.00 49.02  ? 496 LEU B CA  1 
ATOM   3248 C  C   . LEU A 1 496 ? 137.786 108.205 114.435 1.00 49.02  ? 496 LEU B C   1 
ATOM   3249 O  O   . LEU A 1 496 ? 138.454 108.322 113.402 1.00 49.02  ? 496 LEU B O   1 
ATOM   3250 C  CB  . LEU A 1 496 ? 138.944 108.740 116.592 1.00 49.02  ? 496 LEU B CB  1 
ATOM   3251 C  CG  . LEU A 1 496 ? 140.423 108.939 116.271 1.00 49.02  ? 496 LEU B CG  1 
ATOM   3252 C  CD1 . LEU A 1 496 ? 140.720 110.411 116.059 1.00 49.02  ? 496 LEU B CD1 1 
ATOM   3253 C  CD2 . LEU A 1 496 ? 141.276 108.374 117.390 1.00 49.02  ? 496 LEU B CD2 1 
ATOM   3254 N  N   . PHE A 1 497 ? 136.925 107.200 114.610 1.00 52.97  ? 497 PHE B N   1 
ATOM   3255 C  CA  . PHE A 1 497 ? 136.796 106.168 113.582 1.00 52.97  ? 497 PHE B CA  1 
ATOM   3256 C  C   . PHE A 1 497 ? 135.680 106.404 112.573 1.00 52.97  ? 497 PHE B C   1 
ATOM   3257 O  O   . PHE A 1 497 ? 135.795 105.932 111.437 1.00 52.97  ? 497 PHE B O   1 
ATOM   3258 C  CB  . PHE A 1 497 ? 136.607 104.785 114.212 1.00 52.97  ? 497 PHE B CB  1 
ATOM   3259 C  CG  . PHE A 1 497 ? 137.823 104.268 114.915 1.00 52.97  ? 497 PHE B CG  1 
ATOM   3260 C  CD1 . PHE A 1 497 ? 139.060 104.854 114.710 1.00 52.97  ? 497 PHE B CD1 1 
ATOM   3261 C  CD2 . PHE A 1 497 ? 137.741 103.168 115.746 1.00 52.97  ? 497 PHE B CD2 1 
ATOM   3262 C  CE1 . PHE A 1 497 ? 140.185 104.366 115.339 1.00 52.97  ? 497 PHE B CE1 1 
ATOM   3263 C  CE2 . PHE A 1 497 ? 138.863 102.677 116.379 1.00 52.97  ? 497 PHE B CE2 1 
ATOM   3264 C  CZ  . PHE A 1 497 ? 140.085 103.278 116.174 1.00 52.97  ? 497 PHE B CZ  1 
ATOM   3265 N  N   . LEU A 1 498 ? 134.605 107.099 112.936 1.00 51.18  ? 498 LEU B N   1 
ATOM   3266 C  CA  . LEU A 1 498 ? 133.492 107.261 112.004 1.00 51.18  ? 498 LEU B CA  1 
ATOM   3267 C  C   . LEU A 1 498 ? 133.891 108.003 110.730 1.00 51.18  ? 498 LEU B C   1 
ATOM   3268 O  O   . LEU A 1 498 ? 133.550 107.525 109.631 1.00 51.18  ? 498 LEU B O   1 
ATOM   3269 C  CB  . LEU A 1 498 ? 132.330 107.934 112.744 1.00 51.18  ? 498 LEU B CB  1 
ATOM   3270 C  CG  . LEU A 1 498 ? 130.992 108.148 112.050 1.00 51.18  ? 498 LEU B CG  1 
ATOM   3271 C  CD1 . LEU A 1 498 ? 130.391 106.812 111.693 1.00 51.18  ? 498 LEU B CD1 1 
ATOM   3272 C  CD2 . LEU A 1 498 ? 130.074 108.894 112.987 1.00 51.18  ? 498 LEU B CD2 1 
ATOM   3273 N  N   . PRO A 1 499 ? 134.608 109.136 110.782 1.00 51.26  ? 499 PRO B N   1 
ATOM   3274 C  CA  . PRO A 1 499 ? 135.058 109.773 109.534 1.00 51.26  ? 499 PRO B CA  1 
ATOM   3275 C  C   . PRO A 1 499 ? 136.091 108.968 108.771 1.00 51.26  ? 499 PRO B C   1 
ATOM   3276 O  O   . PRO A 1 499 ? 136.459 109.369 107.660 1.00 51.26  ? 499 PRO B O   1 
ATOM   3277 C  CB  . PRO A 1 499 ? 135.649 111.107 110.010 1.00 51.26  ? 499 PRO B CB  1 
ATOM   3278 C  CG  . PRO A 1 499 ? 135.055 111.336 111.345 1.00 51.26  ? 499 PRO B CG  1 
ATOM   3279 C  CD  . PRO A 1 499 ? 134.929 109.978 111.947 1.00 51.26  ? 499 PRO B CD  1 
ATOM   3280 N  N   . ILE A 1 500 ? 136.594 107.874 109.334 1.00 52.62  ? 500 ILE B N   1 
ATOM   3281 C  CA  . ILE A 1 500 ? 137.457 106.964 108.591 1.00 52.62  ? 500 ILE B CA  1 
ATOM   3282 C  C   . ILE A 1 500 ? 136.657 105.807 108.011 1.00 52.62  ? 500 ILE B C   1 
ATOM   3283 O  O   . ILE A 1 500 ? 136.906 105.374 106.883 1.00 52.62  ? 500 ILE B O   1 
ATOM   3284 C  CB  . ILE A 1 500 ? 138.599 106.463 109.498 1.00 52.62  ? 500 ILE B CB  1 
ATOM   3285 C  CG1 . ILE A 1 500 ? 139.506 107.626 109.899 1.00 52.62  ? 500 ILE B CG1 1 
ATOM   3286 C  CG2 . ILE A 1 500 ? 139.399 105.371 108.808 1.00 52.62  ? 500 ILE B CG2 1 
ATOM   3287 C  CD1 . ILE A 1 500 ? 140.555 107.258 110.922 1.00 52.62  ? 500 ILE B CD1 1 
ATOM   3288 N  N   . LEU A 1 501 ? 135.681 105.304 108.768 1.00 56.62  ? 501 LEU B N   1 
ATOM   3289 C  CA  . LEU A 1 501 ? 134.863 104.196 108.288 1.00 56.62  ? 501 LEU B CA  1 
ATOM   3290 C  C   . LEU A 1 501 ? 133.975 104.619 107.125 1.00 56.62  ? 501 LEU B C   1 
ATOM   3291 O  O   . LEU A 1 501 ? 133.768 103.842 106.186 1.00 56.62  ? 501 LEU B O   1 
ATOM   3292 C  CB  . LEU A 1 501 ? 134.018 103.633 109.428 1.00 56.62  ? 501 LEU B CB  1 
ATOM   3293 C  CG  . LEU A 1 501 ? 134.764 102.802 110.471 1.00 56.62  ? 501 LEU B CG  1 
ATOM   3294 C  CD1 . LEU A 1 501 ? 133.900 102.593 111.700 1.00 56.62  ? 501 LEU B CD1 1 
ATOM   3295 C  CD2 . LEU A 1 501 ? 135.198 101.472 109.883 1.00 56.62  ? 501 LEU B CD2 1 
ATOM   3296 N  N   . SER A 1 502 ? 133.431 105.838 107.171 1.00 58.58  ? 502 SER B N   1 
ATOM   3297 C  CA  . SER A 1 502 ? 132.509 106.259 106.115 1.00 58.58  ? 502 SER B CA  1 
ATOM   3298 C  C   . SER A 1 502 ? 133.144 106.265 104.727 1.00 58.58  ? 502 SER B C   1 
ATOM   3299 O  O   . SER A 1 502 ? 132.537 105.703 103.796 1.00 58.58  ? 502 SER B O   1 
ATOM   3300 C  CB  . SER A 1 502 ? 131.910 107.624 106.468 1.00 58.58  ? 502 SER B CB  1 
ATOM   3301 O  OG  . SER A 1 502 ? 131.455 107.640 107.808 1.00 58.58  ? 502 SER B OG  1 
ATOM   3302 N  N   . PRO A 1 503 ? 134.320 106.868 104.500 1.00 60.48  ? 503 PRO B N   1 
ATOM   3303 C  CA  . PRO A 1 503 ? 134.930 106.758 103.163 1.00 60.48  ? 503 PRO B CA  1 
ATOM   3304 C  C   . PRO A 1 503 ? 135.242 105.329 102.768 1.00 60.48  ? 503 PRO B C   1 
ATOM   3305 O  O   . PRO A 1 503 ? 135.113 104.973 101.590 1.00 60.48  ? 503 PRO B O   1 
ATOM   3306 C  CB  . PRO A 1 503 ? 136.204 107.605 103.289 1.00 60.48  ? 503 PRO B CB  1 
ATOM   3307 C  CG  . PRO A 1 503 ? 135.942 108.521 104.425 1.00 60.48  ? 503 PRO B CG  1 
ATOM   3308 C  CD  . PRO A 1 503 ? 135.131 107.719 105.386 1.00 60.48  ? 503 PRO B CD  1 
ATOM   3309 N  N   . LEU A 1 504 ? 135.649 104.494 103.726 1.00 62.40  ? 504 LEU B N   1 
ATOM   3310 C  CA  . LEU A 1 504 ? 135.873 103.084 103.429 1.00 62.40  ? 504 LEU B CA  1 
ATOM   3311 C  C   . LEU A 1 504 ? 134.569 102.402 103.039 1.00 62.40  ? 504 LEU B C   1 
ATOM   3312 O  O   . LEU A 1 504 ? 134.549 101.548 102.146 1.00 62.40  ? 504 LEU B O   1 
ATOM   3313 C  CB  . LEU A 1 504 ? 136.525 102.397 104.633 1.00 62.40  ? 504 LEU B CB  1 
ATOM   3314 C  CG  . LEU A 1 504 ? 136.921 100.917 104.603 1.00 62.40  ? 504 LEU B CG  1 
ATOM   3315 C  CD1 . LEU A 1 504 ? 137.983 100.665 105.654 1.00 62.40  ? 504 LEU B CD1 1 
ATOM   3316 C  CD2 . LEU A 1 504 ? 135.737 100.003 104.869 1.00 62.40  ? 504 LEU B CD2 1 
ATOM   3317 N  N   . ALA A 1 505 ? 133.472 102.763 103.706 1.00 66.80  ? 505 ALA B N   1 
ATOM   3318 C  CA  . ALA A 1 505 ? 132.171 102.211 103.345 1.00 66.80  ? 505 ALA B CA  1 
ATOM   3319 C  C   . ALA A 1 505 ? 131.781 102.606 101.928 1.00 66.80  ? 505 ALA B C   1 
ATOM   3320 O  O   . ALA A 1 505 ? 131.276 101.778 101.161 1.00 66.80  ? 505 ALA B O   1 
ATOM   3321 C  CB  . ALA A 1 505 ? 131.110 102.675 104.341 1.00 66.80  ? 505 ALA B CB  1 
ATOM   3322 N  N   . GLU A 1 506 ? 132.010 103.868 101.559 1.00 68.50  ? 506 GLU B N   1 
ATOM   3323 C  CA  . GLU A 1 506 ? 131.663 104.311 100.214 1.00 68.50  ? 506 GLU B CA  1 
ATOM   3324 C  C   . GLU A 1 506 ? 132.614 103.763 99.156  1.00 68.50  ? 506 GLU B C   1 
ATOM   3325 O  O   . GLU A 1 506 ? 132.236 103.688 97.983  1.00 68.50  ? 506 GLU B O   1 
ATOM   3326 C  CB  . GLU A 1 506 ? 131.639 105.838 100.150 1.00 68.50  ? 506 GLU B CB  1 
ATOM   3327 C  CG  . GLU A 1 506 ? 130.630 106.480 101.086 1.00 68.50  ? 506 GLU B CG  1 
ATOM   3328 C  CD  . GLU A 1 506 ? 130.751 107.990 101.128 1.00 68.50  ? 506 GLU B CD  1 
ATOM   3329 O  OE1 . GLU A 1 506 ? 131.539 108.547 100.336 1.00 68.50  ? 506 GLU B OE1 1 
ATOM   3330 O  OE2 . GLU A 1 506 ? 130.059 108.621 101.954 1.00 68.50  ? 506 GLU B OE2 1 
ATOM   3331 N  N   . ALA A 1 507 ? 133.834 103.382 99.540  1.00 69.58  ? 507 ALA B N   1 
ATOM   3332 C  CA  . ALA A 1 507 ? 134.808 102.910 98.561  1.00 69.58  ? 507 ALA B CA  1 
ATOM   3333 C  C   . ALA A 1 507 ? 134.501 101.495 98.084  1.00 69.58  ? 507 ALA B C   1 
ATOM   3334 O  O   . ALA A 1 507 ? 134.645 101.197 96.894  1.00 69.58  ? 507 ALA B O   1 
ATOM   3335 C  CB  . ALA A 1 507 ? 136.217 102.975 99.151  1.00 69.58  ? 507 ALA B CB  1 
ATOM   3336 N  N   . ILE A 1 508 ? 134.077 100.609 98.992  1.00 71.75  ? 508 ILE B N   1 
ATOM   3337 C  CA  . ILE A 1 508 ? 133.823 99.217  98.634  1.00 71.75  ? 508 ILE B CA  1 
ATOM   3338 C  C   . ILE A 1 508 ? 132.467 99.040  97.957  1.00 71.75  ? 508 ILE B C   1 
ATOM   3339 O  O   . ILE A 1 508 ? 132.107 97.915  97.581  1.00 71.75  ? 508 ILE B O   1 
ATOM   3340 C  CB  . ILE A 1 508 ? 133.965 98.336  99.897  1.00 71.75  ? 508 ILE B CB  1 
ATOM   3341 C  CG1 . ILE A 1 508 ? 135.297 98.624  100.583 1.00 71.75  ? 508 ILE B CG1 1 
ATOM   3342 C  CG2 . ILE A 1 508 ? 133.969 96.852  99.559  1.00 71.75  ? 508 ILE B CG2 1 
ATOM   3343 C  CD1 . ILE A 1 508 ? 135.440 97.952  101.926 1.00 71.75  ? 508 ILE B CD1 1 
ATOM   3344 N  N   . HIS A 1 509 ? 131.715 100.124 97.762  1.00 70.51  ? 509 HIS B N   1 
ATOM   3345 C  CA  . HIS A 1 509 ? 130.395 100.083 97.131  1.00 70.51  ? 509 HIS B CA  1 
ATOM   3346 C  C   . HIS A 1 509 ? 129.441 99.208  97.948  1.00 70.51  ? 509 HIS B C   1 
ATOM   3347 O  O   . HIS A 1 509 ? 128.857 98.237  97.463  1.00 70.51  ? 509 HIS B O   1 
ATOM   3348 C  CB  . HIS A 1 509 ? 130.496 99.612  95.675  1.00 70.51  ? 509 HIS B CB  1 
ATOM   3349 C  CG  . HIS A 1 509 ? 129.189 99.604  94.945  1.00 70.51  ? 509 HIS B CG  1 
ATOM   3350 N  ND1 . HIS A 1 509 ? 128.219 100.563 95.145  1.00 70.51  ? 509 HIS B ND1 1 
ATOM   3351 C  CD2 . HIS A 1 509 ? 128.689 98.749  94.022  1.00 70.51  ? 509 HIS B CD2 1 
ATOM   3352 C  CE1 . HIS A 1 509 ? 127.179 100.301 94.373  1.00 70.51  ? 509 HIS B CE1 1 
ATOM   3353 N  NE2 . HIS A 1 509 ? 127.438 99.206  93.682  1.00 70.51  ? 509 HIS B NE2 1 
ATOM   3354 N  N   . VAL A 1 510 ? 129.311 99.568  99.224  1.00 69.24  ? 510 VAL B N   1 
ATOM   3355 C  CA  . VAL A 1 510 ? 128.418 98.895  100.155 1.00 69.24  ? 510 VAL B CA  1 
ATOM   3356 C  C   . VAL A 1 510 ? 127.644 99.963  100.915 1.00 69.24  ? 510 VAL B C   1 
ATOM   3357 O  O   . VAL A 1 510 ? 128.049 101.125 100.986 1.00 69.24  ? 510 VAL B O   1 
ATOM   3358 C  CB  . VAL A 1 510 ? 129.180 97.968  101.129 1.00 69.24  ? 510 VAL B CB  1 
ATOM   3359 C  CG1 . VAL A 1 510 ? 129.880 98.780  102.209 1.00 69.24  ? 510 VAL B CG1 1 
ATOM   3360 C  CG2 . VAL A 1 510 ? 128.248 96.925  101.734 1.00 69.24  ? 510 VAL B CG2 1 
ATOM   3361 N  N   . ASN A 1 511 ? 126.511 99.557  101.474 1.00 65.54  ? 511 ASN B N   1 
ATOM   3362 C  CA  . ASN A 1 511 ? 125.677 100.486 102.220 1.00 65.54  ? 511 ASN B CA  1 
ATOM   3363 C  C   . ASN A 1 511 ? 126.458 101.036 103.409 1.00 65.54  ? 511 ASN B C   1 
ATOM   3364 O  O   . ASN A 1 511 ? 126.994 100.254 104.206 1.00 65.54  ? 511 ASN B O   1 
ATOM   3365 C  CB  . ASN A 1 511 ? 124.405 99.787  102.697 1.00 65.54  ? 511 ASN B CB  1 
ATOM   3366 C  CG  . ASN A 1 511 ? 123.248 100.744 102.891 1.00 65.54  ? 511 ASN B CG  1 
ATOM   3367 O  OD1 . ASN A 1 511 ? 123.440 101.910 103.226 1.00 65.54  ? 511 ASN B OD1 1 
ATOM   3368 N  ND2 . ASN A 1 511 ? 122.033 100.251 102.681 1.00 65.54  ? 511 ASN B ND2 1 
ATOM   3369 N  N   . PRO A 1 512 ? 126.568 102.359 103.554 1.00 61.49  ? 512 PRO B N   1 
ATOM   3370 C  CA  . PRO A 1 512 ? 127.306 102.907 104.703 1.00 61.49  ? 512 PRO B CA  1 
ATOM   3371 C  C   . PRO A 1 512 ? 126.752 102.463 106.044 1.00 61.49  ? 512 PRO B C   1 
ATOM   3372 O  O   . PRO A 1 512 ? 127.530 102.256 106.983 1.00 61.49  ? 512 PRO B O   1 
ATOM   3373 C  CB  . PRO A 1 512 ? 127.174 104.423 104.510 1.00 61.49  ? 512 PRO B CB  1 
ATOM   3374 C  CG  . PRO A 1 512 ? 126.961 104.597 103.049 1.00 61.49  ? 512 PRO B CG  1 
ATOM   3375 C  CD  . PRO A 1 512 ? 126.168 103.406 102.600 1.00 61.49  ? 512 PRO B CD  1 
ATOM   3376 N  N   . LEU A 1 513 ? 125.432 102.300 106.159 1.00 60.96  ? 513 LEU B N   1 
ATOM   3377 C  CA  . LEU A 1 513 ? 124.852 101.819 107.409 1.00 60.96  ? 513 LEU B CA  1 
ATOM   3378 C  C   . LEU A 1 513 ? 125.385 100.442 107.771 1.00 60.96  ? 513 LEU B C   1 
ATOM   3379 O  O   . LEU A 1 513 ? 125.646 100.164 108.947 1.00 60.96  ? 513 LEU B O   1 
ATOM   3380 C  CB  . LEU A 1 513 ? 123.329 101.794 107.308 1.00 60.96  ? 513 LEU B CB  1 
ATOM   3381 C  CG  . LEU A 1 513 ? 122.634 103.147 107.202 1.00 60.96  ? 513 LEU B CG  1 
ATOM   3382 C  CD1 . LEU A 1 513 ? 121.207 103.039 107.695 1.00 60.96  ? 513 LEU B CD1 1 
ATOM   3383 C  CD2 . LEU A 1 513 ? 123.391 104.149 108.039 1.00 60.96  ? 513 LEU B CD2 1 
ATOM   3384 N  N   . TYR A 1 514 ? 125.569 99.575  106.772 1.00 61.25  ? 514 TYR B N   1 
ATOM   3385 C  CA  . TYR A 1 514 ? 126.089 98.236  107.027 1.00 61.25  ? 514 TYR B CA  1 
ATOM   3386 C  C   . TYR A 1 514 ? 127.409 98.282  107.781 1.00 61.25  ? 514 TYR B C   1 
ATOM   3387 O  O   . TYR A 1 514 ? 127.667 97.420  108.626 1.00 61.25  ? 514 TYR B O   1 
ATOM   3388 C  CB  . TYR A 1 514 ? 126.257 97.486  105.707 1.00 61.25  ? 514 TYR B CB  1 
ATOM   3389 C  CG  . TYR A 1 514 ? 126.539 96.011  105.859 1.00 61.25  ? 514 TYR B CG  1 
ATOM   3390 C  CD1 . TYR A 1 514 ? 125.523 95.119  106.166 1.00 61.25  ? 514 TYR B CD1 1 
ATOM   3391 C  CD2 . TYR A 1 514 ? 127.820 95.510  105.685 1.00 61.25  ? 514 TYR B CD2 1 
ATOM   3392 C  CE1 . TYR A 1 514 ? 125.775 93.769  106.300 1.00 61.25  ? 514 TYR B CE1 1 
ATOM   3393 C  CE2 . TYR A 1 514 ? 128.082 94.161  105.818 1.00 61.25  ? 514 TYR B CE2 1 
ATOM   3394 C  CZ  . TYR A 1 514 ? 127.056 93.295  106.125 1.00 61.25  ? 514 TYR B CZ  1 
ATOM   3395 O  OH  . TYR A 1 514 ? 127.313 91.951  106.258 1.00 61.25  ? 514 TYR B OH  1 
ATOM   3396 N  N   . ILE A 1 515 ? 128.242 99.282  107.507 1.00 59.05  ? 515 ILE B N   1 
ATOM   3397 C  CA  . ILE A 1 515 ? 129.504 99.445  108.220 1.00 59.05  ? 515 ILE B CA  1 
ATOM   3398 C  C   . ILE A 1 515 ? 129.302 100.175 109.543 1.00 59.05  ? 515 ILE B C   1 
ATOM   3399 O  O   . ILE A 1 515 ? 129.847 99.769  110.572 1.00 59.05  ? 515 ILE B O   1 
ATOM   3400 C  CB  . ILE A 1 515 ? 130.518 100.191 107.328 1.00 59.05  ? 515 ILE B CB  1 
ATOM   3401 C  CG1 . ILE A 1 515 ? 130.703 99.485  105.983 1.00 59.05  ? 515 ILE B CG1 1 
ATOM   3402 C  CG2 . ILE A 1 515 ? 131.854 100.316 108.038 1.00 59.05  ? 515 ILE B CG2 1 
ATOM   3403 C  CD1 . ILE A 1 515 ? 131.327 98.123  106.074 1.00 59.05  ? 515 ILE B CD1 1 
ATOM   3404 N  N   . LEU A 1 516 ? 128.516 101.255 109.532 1.00 56.61  ? 516 LEU B N   1 
ATOM   3405 C  CA  . LEU A 1 516 ? 128.480 102.164 110.674 1.00 56.61  ? 516 LEU B CA  1 
ATOM   3406 C  C   . LEU A 1 516 ? 127.698 101.585 111.849 1.00 56.61  ? 516 LEU B C   1 
ATOM   3407 O  O   . LEU A 1 516 ? 128.121 101.723 113.003 1.00 56.61  ? 516 LEU B O   1 
ATOM   3408 C  CB  . LEU A 1 516 ? 127.889 103.508 110.254 1.00 56.61  ? 516 LEU B CB  1 
ATOM   3409 C  CG  . LEU A 1 516 ? 128.610 104.248 109.126 1.00 56.61  ? 516 LEU B CG  1 
ATOM   3410 C  CD1 . LEU A 1 516 ? 128.152 105.693 109.052 1.00 56.61  ? 516 LEU B CD1 1 
ATOM   3411 C  CD2 . LEU A 1 516 ? 130.116 104.161 109.290 1.00 56.61  ? 516 LEU B CD2 1 
ATOM   3412 N  N   . ILE A 1 517 ? 126.549 100.954 111.587 1.00 55.69  ? 517 ILE B N   1 
ATOM   3413 C  CA  . ILE A 1 517 ? 125.685 100.506 112.682 1.00 55.69  ? 517 ILE B CA  1 
ATOM   3414 C  C   . ILE A 1 517 ? 126.371 99.495  113.595 1.00 55.69  ? 517 ILE B C   1 
ATOM   3415 O  O   . ILE A 1 517 ? 126.336 99.685  114.822 1.00 55.69  ? 517 ILE B O   1 
ATOM   3416 C  CB  . ILE A 1 517 ? 124.346 99.991  112.125 1.00 55.69  ? 517 ILE B CB  1 
ATOM   3417 C  CG1 . ILE A 1 517 ? 123.591 101.118 111.423 1.00 55.69  ? 517 ILE B CG1 1 
ATOM   3418 C  CG2 . ILE A 1 517 ? 123.506 99.393  113.233 1.00 55.69  ? 517 ILE B CG2 1 
ATOM   3419 C  CD1 . ILE A 1 517 ? 122.398 100.644 110.632 1.00 55.69  ? 517 ILE B CD1 1 
ATOM   3420 N  N   . PRO A 1 518 ? 126.988 98.415  113.094 1.00 55.26  ? 518 PRO B N   1 
ATOM   3421 C  CA  . PRO A 1 518 ? 127.707 97.527  114.024 1.00 55.26  ? 518 PRO B CA  1 
ATOM   3422 C  C   . PRO A 1 518 ? 128.807 98.241  114.782 1.00 55.26  ? 518 PRO B C   1 
ATOM   3423 O  O   . PRO A 1 518 ? 128.969 98.017  115.987 1.00 55.26  ? 518 PRO B O   1 
ATOM   3424 C  CB  . PRO A 1 518 ? 128.271 96.419  113.124 1.00 55.26  ? 518 PRO B CB  1 
ATOM   3425 C  CG  . PRO A 1 518 ? 127.719 96.623  111.788 1.00 55.26  ? 518 PRO B CG  1 
ATOM   3426 C  CD  . PRO A 1 518 ? 127.036 97.935  111.701 1.00 55.26  ? 518 PRO B CD  1 
ATOM   3427 N  N   . SER A 1 519 ? 129.552 99.123  114.114 1.00 51.69  ? 519 SER B N   1 
ATOM   3428 C  CA  . SER A 1 519 ? 130.619 99.850  114.792 1.00 51.69  ? 519 SER B CA  1 
ATOM   3429 C  C   . SER A 1 519 ? 130.062 100.808 115.836 1.00 51.69  ? 519 SER B C   1 
ATOM   3430 O  O   . SER A 1 519 ? 130.602 100.909 116.944 1.00 51.69  ? 519 SER B O   1 
ATOM   3431 C  CB  . SER A 1 519 ? 131.469 100.604 113.773 1.00 51.69  ? 519 SER B CB  1 
ATOM   3432 O  OG  . SER A 1 519 ? 132.440 101.403 114.421 1.00 51.69  ? 519 SER B OG  1 
ATOM   3433 N  N   . THR A 1 520 ? 128.984 101.521 115.504 1.00 51.28  ? 520 THR B N   1 
ATOM   3434 C  CA  . THR A 1 520 ? 128.389 102.444 116.465 1.00 51.28  ? 520 THR B CA  1 
ATOM   3435 C  C   . THR A 1 520 ? 127.855 101.705 117.684 1.00 51.28  ? 520 THR B C   1 
ATOM   3436 O  O   . THR A 1 520 ? 128.029 102.159 118.820 1.00 51.28  ? 520 THR B O   1 
ATOM   3437 C  CB  . THR A 1 520 ? 127.276 103.252 115.802 1.00 51.28  ? 520 THR B CB  1 
ATOM   3438 O  OG1 . THR A 1 520 ? 127.794 103.917 114.644 1.00 51.28  ? 520 THR B OG1 1 
ATOM   3439 C  CG2 . THR A 1 520 ? 126.727 104.286 116.768 1.00 51.28  ? 520 THR B CG2 1 
ATOM   3440 N  N   . LEU A 1 521 ? 127.196 100.564 117.469 1.00 48.62  ? 521 LEU B N   1 
ATOM   3441 C  CA  . LEU A 1 521 ? 126.709 99.777  118.597 1.00 48.62  ? 521 LEU B CA  1 
ATOM   3442 C  C   . LEU A 1 521 ? 127.863 99.242  119.434 1.00 48.62  ? 521 LEU B C   1 
ATOM   3443 O  O   . LEU A 1 521 ? 127.809 99.273  120.668 1.00 48.62  ? 521 LEU B O   1 
ATOM   3444 C  CB  . LEU A 1 521 ? 125.832 98.630  118.100 1.00 48.62  ? 521 LEU B CB  1 
ATOM   3445 C  CG  . LEU A 1 521 ? 124.433 99.005  117.618 1.00 48.62  ? 521 LEU B CG  1 
ATOM   3446 C  CD1 . LEU A 1 521 ? 123.657 97.760  117.234 1.00 48.62  ? 521 LEU B CD1 1 
ATOM   3447 C  CD2 . LEU A 1 521 ? 123.698 99.789  118.685 1.00 48.62  ? 521 LEU B CD2 1 
ATOM   3448 N  N   . CYS A 1 522 ? 128.920 98.752  118.783 1.00 51.19  ? 522 CYS B N   1 
ATOM   3449 C  CA  . CYS A 1 522 ? 130.037 98.164  119.507 1.00 51.19  ? 522 CYS B CA  1 
ATOM   3450 C  C   . CYS A 1 522 ? 130.894 99.208  120.207 1.00 51.19  ? 522 CYS B C   1 
ATOM   3451 O  O   . CYS A 1 522 ? 131.667 98.852  121.102 1.00 51.19  ? 522 CYS B O   1 
ATOM   3452 C  CB  . CYS A 1 522 ? 130.899 97.342  118.551 1.00 51.19  ? 522 CYS B CB  1 
ATOM   3453 S  SG  . CYS A 1 522 ? 130.246 95.699  118.192 1.00 51.19  ? 522 CYS B SG  1 
ATOM   3454 N  N   . THR A 1 523 ? 130.784 100.480 119.817 1.00 48.69  ? 523 THR B N   1 
ATOM   3455 C  CA  . THR A 1 523 ? 131.564 101.519 120.481 1.00 48.69  ? 523 THR B CA  1 
ATOM   3456 C  C   . THR A 1 523 ? 131.217 101.611 121.961 1.00 48.69  ? 523 THR B C   1 
ATOM   3457 O  O   . THR A 1 523 ? 132.106 101.766 122.806 1.00 48.69  ? 523 THR B O   1 
ATOM   3458 C  CB  . THR A 1 523 ? 131.336 102.867 119.800 1.00 48.69  ? 523 THR B CB  1 
ATOM   3459 O  OG1 . THR A 1 523 ? 131.657 102.764 118.409 1.00 48.69  ? 523 THR B OG1 1 
ATOM   3460 C  CG2 . THR A 1 523 ? 132.209 103.934 120.435 1.00 48.69  ? 523 THR B CG2 1 
ATOM   3461 N  N   . SER A 1 524 ? 129.930 101.512 122.295 1.00 45.14  ? 524 SER B N   1 
ATOM   3462 C  CA  . SER A 1 524 ? 129.513 101.605 123.687 1.00 45.14  ? 524 SER B CA  1 
ATOM   3463 C  C   . SER A 1 524 ? 129.940 100.396 124.506 1.00 45.14  ? 524 SER B C   1 
ATOM   3464 O  O   . SER A 1 524 ? 129.876 100.446 125.738 1.00 45.14  ? 524 SER B O   1 
ATOM   3465 C  CB  . SER A 1 524 ? 127.997 101.776 123.772 1.00 45.14  ? 524 SER B CB  1 
ATOM   3466 O  OG  . SER A 1 524 ? 127.551 102.815 122.919 1.00 45.14  ? 524 SER B OG  1 
ATOM   3467 N  N   . PHE A 1 525 ? 130.372 99.315  123.860 1.00 46.16  ? 525 PHE B N   1 
ATOM   3468 C  CA  . PHE A 1 525 ? 130.802 98.116  124.576 1.00 46.16  ? 525 PHE B CA  1 
ATOM   3469 C  C   . PHE A 1 525 ? 132.219 98.348  125.078 1.00 46.16  ? 525 PHE B C   1 
ATOM   3470 O  O   . PHE A 1 525 ? 133.205 97.986  124.435 1.00 46.16  ? 525 PHE B O   1 
ATOM   3471 C  CB  . PHE A 1 525 ? 130.707 96.885  123.685 1.00 46.16  ? 525 PHE B CB  1 
ATOM   3472 C  CG  . PHE A 1 525 ? 129.302 96.537  123.287 1.00 46.16  ? 525 PHE B CG  1 
ATOM   3473 C  CD1 . PHE A 1 525 ? 128.226 97.000  124.023 1.00 46.16  ? 525 PHE B CD1 1 
ATOM   3474 C  CD2 . PHE A 1 525 ? 129.056 95.746  122.180 1.00 46.16  ? 525 PHE B CD2 1 
ATOM   3475 C  CE1 . PHE A 1 525 ? 126.932 96.686  123.661 1.00 46.16  ? 525 PHE B CE1 1 
ATOM   3476 C  CE2 . PHE A 1 525 ? 127.763 95.428  121.813 1.00 46.16  ? 525 PHE B CE2 1 
ATOM   3477 C  CZ  . PHE A 1 525 ? 126.701 95.899  122.555 1.00 46.16  ? 525 PHE B CZ  1 
ATOM   3478 N  N   . ALA A 1 526 ? 132.311 98.953  126.258 1.00 51.44  ? 526 ALA B N   1 
ATOM   3479 C  CA  . ALA A 1 526 ? 133.567 99.316  126.903 1.00 51.44  ? 526 ALA B CA  1 
ATOM   3480 C  C   . ALA A 1 526 ? 133.595 98.772  128.322 1.00 51.44  ? 526 ALA B C   1 
ATOM   3481 O  O   . ALA A 1 526 ? 133.871 99.482  129.291 1.00 51.44  ? 526 ALA B O   1 
ATOM   3482 C  CB  . ALA A 1 526 ? 133.760 100.828 126.897 1.00 51.44  ? 526 ALA B CB  1 
ATOM   3483 N  N   . PHE A 1 527 ? 133.298 97.482  128.458 1.00 50.88  ? 527 PHE B N   1 
ATOM   3484 C  CA  . PHE A 1 527 ? 132.976 96.894  129.756 1.00 50.88  ? 527 PHE B CA  1 
ATOM   3485 C  C   . PHE A 1 527 ? 134.200 96.358  130.483 1.00 50.88  ? 527 PHE B C   1 
ATOM   3486 O  O   . PHE A 1 527 ? 134.137 95.258  131.028 1.00 50.88  ? 527 PHE B O   1 
ATOM   3487 C  CB  . PHE A 1 527 ? 131.971 95.768  129.544 1.00 50.88  ? 527 PHE B CB  1 
ATOM   3488 C  CG  . PHE A 1 527 ? 130.632 96.223  129.047 1.00 50.88  ? 527 PHE B CG  1 
ATOM   3489 C  CD1 . PHE A 1 527 ? 129.696 96.746  129.905 1.00 50.88  ? 527 PHE B CD1 1 
ATOM   3490 C  CD2 . PHE A 1 527 ? 130.300 96.083  127.715 1.00 50.88  ? 527 PHE B CD2 1 
ATOM   3491 C  CE1 . PHE A 1 527 ? 128.464 97.143  129.445 1.00 50.88  ? 527 PHE B CE1 1 
ATOM   3492 C  CE2 . PHE A 1 527 ? 129.069 96.480  127.250 1.00 50.88  ? 527 PHE B CE2 1 
ATOM   3493 C  CZ  . PHE A 1 527 ? 128.151 97.016  128.112 1.00 50.88  ? 527 PHE B CZ  1 
ATOM   3494 N  N   . LEU A 1 528 ? 135.306 97.071  130.557 1.00 54.83  ? 528 LEU B N   1 
ATOM   3495 C  CA  . LEU A 1 528 ? 136.437 96.389  131.184 1.00 54.83  ? 528 LEU B CA  1 
ATOM   3496 C  C   . LEU A 1 528 ? 137.147 97.210  132.248 1.00 54.83  ? 528 LEU B C   1 
ATOM   3497 O  O   . LEU A 1 528 ? 137.536 96.655  133.277 1.00 54.83  ? 528 LEU B O   1 
ATOM   3498 C  CB  . LEU A 1 528 ? 137.463 95.937  130.126 1.00 54.83  ? 528 LEU B CB  1 
ATOM   3499 C  CG  . LEU A 1 528 ? 137.300 94.544  129.506 1.00 54.83  ? 528 LEU B CG  1 
ATOM   3500 C  CD1 . LEU A 1 528 ? 136.135 94.466  128.542 1.00 54.83  ? 528 LEU B CD1 1 
ATOM   3501 C  CD2 . LEU A 1 528 ? 138.588 94.111  128.821 1.00 54.83  ? 528 LEU B CD2 1 
ATOM   3502 N  N   . LEU A 1 529 ? 137.327 98.506  132.034 1.00 56.47  ? 529 LEU B N   1 
ATOM   3503 C  CA  . LEU A 1 529 ? 138.134 99.289  132.953 1.00 56.47  ? 529 LEU B CA  1 
ATOM   3504 C  C   . LEU A 1 529 ? 137.377 100.528 133.400 1.00 56.47  ? 529 LEU B C   1 
ATOM   3505 O  O   . LEU A 1 529 ? 136.513 101.032 132.676 1.00 56.47  ? 529 LEU B O   1 
ATOM   3506 C  CB  . LEU A 1 529 ? 139.463 99.702  132.304 1.00 56.47  ? 529 LEU B CB  1 
ATOM   3507 C  CG  . LEU A 1 529 ? 140.319 98.574  131.725 1.00 56.47  ? 529 LEU B CG  1 
ATOM   3508 C  CD1 . LEU A 1 529 ? 141.311 99.118  130.714 1.00 56.47  ? 529 LEU B CD1 1 
ATOM   3509 C  CD2 . LEU A 1 529 ? 141.039 97.819  132.830 1.00 56.47  ? 529 LEU B CD2 1 
ATOM   3510 N  N   . PRO A 1 530 ? 137.671 101.030 134.601 1.00 57.74  ? 530 PRO B N   1 
ATOM   3511 C  CA  . PRO A 1 530 ? 137.029 102.274 135.050 1.00 57.74  ? 530 PRO B CA  1 
ATOM   3512 C  C   . PRO A 1 530 ? 137.300 103.453 134.136 1.00 57.74  ? 530 PRO B C   1 
ATOM   3513 O  O   . PRO A 1 530 ? 136.457 104.352 134.031 1.00 57.74  ? 530 PRO B O   1 
ATOM   3514 C  CB  . PRO A 1 530 ? 137.632 102.490 136.445 1.00 57.74  ? 530 PRO B CB  1 
ATOM   3515 C  CG  . PRO A 1 530 ? 138.064 101.131 136.883 1.00 57.74  ? 530 PRO B CG  1 
ATOM   3516 C  CD  . PRO A 1 530 ? 138.523 100.437 135.643 1.00 57.74  ? 530 PRO B CD  1 
ATOM   3517 N  N   . VAL A 1 531 ? 138.455 103.477 133.467 1.00 57.92  ? 531 VAL B N   1 
ATOM   3518 C  CA  . VAL A 1 531 ? 138.783 104.566 132.556 1.00 57.92  ? 531 VAL B CA  1 
ATOM   3519 C  C   . VAL A 1 531 ? 137.990 104.503 131.260 1.00 57.92  ? 531 VAL B C   1 
ATOM   3520 O  O   . VAL A 1 531 ? 137.978 105.482 130.505 1.00 57.92  ? 531 VAL B O   1 
ATOM   3521 C  CB  . VAL A 1 531 ? 140.298 104.557 132.261 1.00 57.92  ? 531 VAL B CB  1 
ATOM   3522 C  CG1 . VAL A 1 531 ? 140.647 103.444 131.286 1.00 57.92  ? 531 VAL B CG1 1 
ATOM   3523 C  CG2 . VAL A 1 531 ? 140.765 105.914 131.747 1.00 57.92  ? 531 VAL B CG2 1 
ATOM   3524 N  N   . ALA A 1 532 ? 137.317 103.383 130.988 1.00 57.95  ? 532 ALA B N   1 
ATOM   3525 C  CA  . ALA A 1 532 ? 136.631 103.216 129.710 1.00 57.95  ? 532 ALA B CA  1 
ATOM   3526 C  C   . ALA A 1 532 ? 135.512 104.236 129.537 1.00 57.95  ? 532 ALA B C   1 
ATOM   3527 O  O   . ALA A 1 532 ? 135.450 104.938 128.522 1.00 57.95  ? 532 ALA B O   1 
ATOM   3528 C  CB  . ALA A 1 532 ? 136.086 101.794 129.592 1.00 57.95  ? 532 ALA B CB  1 
ATOM   3529 N  N   . ASN A 1 533 ? 134.620 104.335 130.516 1.00 59.22  ? 533 ASN B N   1 
ATOM   3530 C  CA  . ASN A 1 533 ? 133.484 105.239 130.423 1.00 59.22  ? 533 ASN B CA  1 
ATOM   3531 C  C   . ASN A 1 533 ? 133.108 105.694 131.824 1.00 59.22  ? 533 ASN B C   1 
ATOM   3532 O  O   . ASN A 1 533 ? 133.430 105.017 132.808 1.00 59.22  ? 533 ASN B O   1 
ATOM   3533 C  CB  . ASN A 1 533 ? 132.293 104.570 129.723 1.00 59.22  ? 533 ASN B CB  1 
ATOM   3534 C  CG  . ASN A 1 533 ? 132.009 103.188 130.253 1.00 59.22  ? 533 ASN B CG  1 
ATOM   3535 O  OD1 . ASN A 1 533 ? 132.644 102.737 131.203 1.00 59.22  ? 533 ASN B OD1 1 
ATOM   3536 N  ND2 . ASN A 1 533 ? 131.052 102.503 129.640 1.00 59.22  ? 533 ASN B ND2 1 
ATOM   3537 N  N   . PRO A 1 534 ? 132.442 106.840 131.950 1.00 58.08  ? 534 PRO B N   1 
ATOM   3538 C  CA  . PRO A 1 534 ? 132.143 107.403 133.278 1.00 58.08  ? 534 PRO B CA  1 
ATOM   3539 C  C   . PRO A 1 534 ? 131.347 106.467 134.175 1.00 58.08  ? 534 PRO B C   1 
ATOM   3540 O  O   . PRO A 1 534 ? 131.594 106.449 135.390 1.00 58.08  ? 534 PRO B O   1 
ATOM   3541 C  CB  . PRO A 1 534 ? 131.344 108.672 132.946 1.00 58.08  ? 534 PRO B CB  1 
ATOM   3542 C  CG  . PRO A 1 534 ? 131.850 109.078 131.613 1.00 58.08  ? 534 PRO B CG  1 
ATOM   3543 C  CD  . PRO A 1 534 ? 132.156 107.805 130.872 1.00 58.08  ? 534 PRO B CD  1 
ATOM   3544 N  N   . PRO A 1 535 ? 130.359 105.710 133.662 1.00 56.31  ? 535 PRO B N   1 
ATOM   3545 C  CA  . PRO A 1 535 ? 129.620 104.819 134.579 1.00 56.31  ? 535 PRO B CA  1 
ATOM   3546 C  C   . PRO A 1 535 ? 130.503 103.822 135.308 1.00 56.31  ? 535 PRO B C   1 
ATOM   3547 O  O   . PRO A 1 535 ? 130.322 103.601 136.514 1.00 56.31  ? 535 PRO B O   1 
ATOM   3548 C  CB  . PRO A 1 535 ? 128.621 104.117 133.651 1.00 56.31  ? 535 PRO B CB  1 
ATOM   3549 C  CG  . PRO A 1 535 ? 128.384 105.088 132.580 1.00 56.31  ? 535 PRO B CG  1 
ATOM   3550 C  CD  . PRO A 1 535 ? 129.714 105.734 132.334 1.00 56.31  ? 535 PRO B CD  1 
ATOM   3551 N  N   . ASN A 1 536 ? 131.473 103.226 134.611 1.00 56.58  ? 536 ASN B N   1 
ATOM   3552 C  CA  . ASN A 1 536 ? 132.369 102.277 135.262 1.00 56.58  ? 536 ASN B CA  1 
ATOM   3553 C  C   . ASN A 1 536 ? 133.227 102.967 136.313 1.00 56.58  ? 536 ASN B C   1 
ATOM   3554 O  O   . ASN A 1 536 ? 133.467 102.411 137.390 1.00 56.58  ? 536 ASN B O   1 
ATOM   3555 C  CB  . ASN A 1 536 ? 133.245 101.579 134.223 1.00 56.58  ? 536 ASN B CB  1 
ATOM   3556 C  CG  . ASN A 1 536 ? 132.473 100.577 133.392 1.00 56.58  ? 536 ASN B CG  1 
ATOM   3557 O  OD1 . ASN A 1 536 ? 132.872 100.235 132.281 1.00 56.58  ? 536 ASN B OD1 1 
ATOM   3558 N  ND2 . ASN A 1 536 ? 131.361 100.099 133.930 1.00 56.58  ? 536 ASN B ND2 1 
ATOM   3559 N  N   . ALA A 1 537 ? 133.699 104.180 136.018 1.00 57.58  ? 537 ALA B N   1 
ATOM   3560 C  CA  . ALA A 1 537 ? 134.488 104.923 136.994 1.00 57.58  ? 537 ALA B CA  1 
ATOM   3561 C  C   . ALA A 1 537 ? 133.668 105.241 138.236 1.00 57.58  ? 537 ALA B C   1 
ATOM   3562 O  O   . ALA A 1 537 ? 134.158 105.105 139.362 1.00 57.58  ? 537 ALA B O   1 
ATOM   3563 C  CB  . ALA A 1 537 ? 135.028 106.207 136.366 1.00 57.58  ? 537 ALA B CB  1 
ATOM   3564 N  N   . ILE A 1 538 ? 132.415 105.657 138.051 1.00 58.42  ? 538 ILE B N   1 
ATOM   3565 C  CA  . ILE A 1 538 ? 131.555 105.965 139.191 1.00 58.42  ? 538 ILE B CA  1 
ATOM   3566 C  C   . ILE A 1 538 ? 131.315 104.718 140.028 1.00 58.42  ? 538 ILE B C   1 
ATOM   3567 O  O   . ILE A 1 538 ? 131.365 104.760 141.264 1.00 58.42  ? 538 ILE B O   1 
ATOM   3568 C  CB  . ILE A 1 538 ? 130.231 106.585 138.712 1.00 58.42  ? 538 ILE B CB  1 
ATOM   3569 C  CG1 . ILE A 1 538 ? 130.487 107.945 138.069 1.00 58.42  ? 538 ILE B CG1 1 
ATOM   3570 C  CG2 . ILE A 1 538 ? 129.253 106.717 139.865 1.00 58.42  ? 538 ILE B CG2 1 
ATOM   3571 C  CD1 . ILE A 1 538 ? 129.411 108.359 137.113 1.00 58.42  ? 538 ILE B CD1 1 
ATOM   3572 N  N   . VAL A 1 539 ? 131.051 103.588 139.372 1.00 60.46  ? 539 VAL B N   1 
ATOM   3573 C  CA  . VAL A 1 539 ? 130.798 102.353 140.105 1.00 60.46  ? 539 VAL B CA  1 
ATOM   3574 C  C   . VAL A 1 539 ? 132.042 101.916 140.870 1.00 60.46  ? 539 VAL B C   1 
ATOM   3575 O  O   . VAL A 1 539 ? 131.959 101.499 142.032 1.00 60.46  ? 539 VAL B O   1 
ATOM   3576 C  CB  . VAL A 1 539 ? 130.302 101.266 139.138 1.00 60.46  ? 539 VAL B CB  1 
ATOM   3577 C  CG1 . VAL A 1 539 ? 130.426 99.890  139.767 1.00 60.46  ? 539 VAL B CG1 1 
ATOM   3578 C  CG2 . VAL A 1 539 ? 128.874 101.560 138.735 1.00 60.46  ? 539 VAL B CG2 1 
ATOM   3579 N  N   . PHE A 1 540 ? 133.215 102.014 140.241 1.00 63.94  ? 540 PHE B N   1 
ATOM   3580 C  CA  . PHE A 1 540 ? 134.459 101.636 140.900 1.00 63.94  ? 540 PHE B CA  1 
ATOM   3581 C  C   . PHE A 1 540 ? 134.862 102.619 141.992 1.00 63.94  ? 540 PHE B C   1 
ATOM   3582 O  O   . PHE A 1 540 ? 135.650 102.257 142.871 1.00 63.94  ? 540 PHE B O   1 
ATOM   3583 C  CB  . PHE A 1 540 ? 135.575 101.522 139.862 1.00 63.94  ? 540 PHE B CB  1 
ATOM   3584 C  CG  . PHE A 1 540 ? 136.786 100.786 140.351 1.00 63.94  ? 540 PHE B CG  1 
ATOM   3585 C  CD1 . PHE A 1 540 ? 136.803 99.403  140.383 1.00 63.94  ? 540 PHE B CD1 1 
ATOM   3586 C  CD2 . PHE A 1 540 ? 137.909 101.475 140.771 1.00 63.94  ? 540 PHE B CD2 1 
ATOM   3587 C  CE1 . PHE A 1 540 ? 137.916 98.722  140.828 1.00 63.94  ? 540 PHE B CE1 1 
ATOM   3588 C  CE2 . PHE A 1 540 ? 139.026 100.799 141.218 1.00 63.94  ? 540 PHE B CE2 1 
ATOM   3589 C  CZ  . PHE A 1 540 ? 139.029 99.420  141.247 1.00 63.94  ? 540 PHE B CZ  1 
ATOM   3590 N  N   . SER A 1 541 ? 134.342 103.850 141.954 1.00 65.65  ? 541 SER B N   1 
ATOM   3591 C  CA  . SER A 1 541 ? 134.714 104.847 142.954 1.00 65.65  ? 541 SER B CA  1 
ATOM   3592 C  C   . SER A 1 541 ? 134.307 104.428 144.359 1.00 65.65  ? 541 SER B C   1 
ATOM   3593 O  O   . SER A 1 541 ? 134.895 104.897 145.340 1.00 65.65  ? 541 SER B O   1 
ATOM   3594 C  CB  . SER A 1 541 ? 134.086 106.196 142.606 1.00 65.65  ? 541 SER B CB  1 
ATOM   3595 O  OG  . SER A 1 541 ? 132.747 106.264 143.064 1.00 65.65  ? 541 SER B OG  1 
ATOM   3596 N  N   . TYR A 1 542 ? 133.307 103.555 144.482 1.00 69.54  ? 542 TYR B N   1 
ATOM   3597 C  CA  . TYR A 1 542 ? 132.913 103.059 145.794 1.00 69.54  ? 542 TYR B CA  1 
ATOM   3598 C  C   . TYR A 1 542 ? 133.952 102.125 146.398 1.00 69.54  ? 542 TYR B C   1 
ATOM   3599 O  O   . TYR A 1 542 ? 133.847 101.794 147.583 1.00 69.54  ? 542 TYR B O   1 
ATOM   3600 C  CB  . TYR A 1 542 ? 131.553 102.367 145.703 1.00 69.54  ? 542 TYR B CB  1 
ATOM   3601 C  CG  . TYR A 1 542 ? 130.397 103.342 145.700 1.00 69.54  ? 542 TYR B CG  1 
ATOM   3602 C  CD1 . TYR A 1 542 ? 130.226 104.238 144.653 1.00 69.54  ? 542 TYR B CD1 1 
ATOM   3603 C  CD2 . TYR A 1 542 ? 129.487 103.378 146.746 1.00 69.54  ? 542 TYR B CD2 1 
ATOM   3604 C  CE1 . TYR A 1 542 ? 129.180 105.136 144.645 1.00 69.54  ? 542 TYR B CE1 1 
ATOM   3605 C  CE2 . TYR A 1 542 ? 128.436 104.274 146.746 1.00 69.54  ? 542 TYR B CE2 1 
ATOM   3606 C  CZ  . TYR A 1 542 ? 128.288 105.151 145.692 1.00 69.54  ? 542 TYR B CZ  1 
ATOM   3607 O  OH  . TYR A 1 542 ? 127.245 106.046 145.683 1.00 69.54  ? 542 TYR B OH  1 
ATOM   3608 N  N   . GLY A 1 543 ? 134.937 101.692 145.615 1.00 73.73  ? 543 GLY B N   1 
ATOM   3609 C  CA  . GLY A 1 543 ? 136.047 100.918 146.137 1.00 73.73  ? 543 GLY B CA  1 
ATOM   3610 C  C   . GLY A 1 543 ? 135.673 99.557  146.671 1.00 73.73  ? 543 GLY B C   1 
ATOM   3611 O  O   . GLY A 1 543 ? 136.295 99.080  147.625 1.00 73.73  ? 543 GLY B O   1 
ATOM   3612 N  N   . HIS A 1 544 ? 134.674 98.912  146.075 1.00 76.78  ? 544 HIS B N   1 
ATOM   3613 C  CA  . HIS A 1 544 ? 134.252 97.578  146.475 1.00 76.78  ? 544 HIS B CA  1 
ATOM   3614 C  C   . HIS A 1 544 ? 134.405 96.567  145.348 1.00 76.78  ? 544 HIS B C   1 
ATOM   3615 O  O   . HIS A 1 544 ? 133.842 95.470  145.426 1.00 76.78  ? 544 HIS B O   1 
ATOM   3616 C  CB  . HIS A 1 544 ? 132.809 97.621  146.977 1.00 76.78  ? 544 HIS B CB  1 
ATOM   3617 C  CG  . HIS A 1 544 ? 132.648 98.366  148.266 1.00 76.78  ? 544 HIS B CG  1 
ATOM   3618 N  ND1 . HIS A 1 544 ? 131.417 98.682  148.798 1.00 76.78  ? 544 HIS B ND1 1 
ATOM   3619 C  CD2 . HIS A 1 544 ? 133.568 98.852  149.134 1.00 76.78  ? 544 HIS B CD2 1 
ATOM   3620 C  CE1 . HIS A 1 544 ? 131.585 99.334  149.935 1.00 76.78  ? 544 HIS B CE1 1 
ATOM   3621 N  NE2 . HIS A 1 544 ? 132.880 99.450  150.162 1.00 76.78  ? 544 HIS B NE2 1 
ATOM   3622 N  N   . LEU A 1 545 ? 135.154 96.913  144.304 1.00 69.95  ? 545 LEU B N   1 
ATOM   3623 C  CA  . LEU A 1 545 ? 135.423 96.029  143.182 1.00 69.95  ? 545 LEU B CA  1 
ATOM   3624 C  C   . LEU A 1 545 ? 136.923 95.941  142.953 1.00 69.95  ? 545 LEU B C   1 
ATOM   3625 O  O   . LEU A 1 545 ? 137.679 96.841  143.328 1.00 69.95  ? 545 LEU B O   1 
ATOM   3626 C  CB  . LEU A 1 545 ? 134.739 96.518  141.899 1.00 69.95  ? 545 LEU B CB  1 
ATOM   3627 C  CG  . LEU A 1 545 ? 133.358 95.948  141.582 1.00 69.95  ? 545 LEU B CG  1 
ATOM   3628 C  CD1 . LEU A 1 545 ? 132.833 96.536  140.287 1.00 69.95  ? 545 LEU B CD1 1 
ATOM   3629 C  CD2 . LEU A 1 545 ? 133.422 94.435  141.494 1.00 69.95  ? 545 LEU B CD2 1 
ATOM   3630 N  N   . LYS A 1 546 ? 137.346 94.845  142.335 1.00 68.29  ? 546 LYS B N   1 
ATOM   3631 C  CA  . LYS A 1 546 ? 138.727 94.661  141.922 1.00 68.29  ? 546 LYS B CA  1 
ATOM   3632 C  C   . LYS A 1 546 ? 138.802 94.607  140.403 1.00 68.29  ? 546 LYS B C   1 
ATOM   3633 O  O   . LYS A 1 546 ? 137.868 94.156  139.734 1.00 68.29  ? 546 LYS B O   1 
ATOM   3634 C  CB  . LYS A 1 546 ? 139.326 93.387  142.524 1.00 68.29  ? 546 LYS B CB  1 
ATOM   3635 C  CG  . LYS A 1 546 ? 139.556 93.463  144.023 1.00 68.29  ? 546 LYS B CG  1 
ATOM   3636 C  CD  . LYS A 1 546 ? 140.095 92.151  144.567 1.00 68.29  ? 546 LYS B CD  1 
ATOM   3637 C  CE  . LYS A 1 546 ? 139.135 91.005  144.297 1.00 68.29  ? 546 LYS B CE  1 
ATOM   3638 N  NZ  . LYS A 1 546 ? 139.619 89.726  144.886 1.00 68.29  ? 546 LYS B NZ  1 
ATOM   3639 N  N   . VAL A 1 547 ? 139.927 95.081  139.864 1.00 64.09  ? 547 VAL B N   1 
ATOM   3640 C  CA  . VAL A 1 547 ? 140.086 95.167  138.416 1.00 64.09  ? 547 VAL B CA  1 
ATOM   3641 C  C   . VAL A 1 547 ? 140.004 93.789  137.776 1.00 64.09  ? 547 VAL B C   1 
ATOM   3642 O  O   . VAL A 1 547 ? 139.454 93.639  136.678 1.00 64.09  ? 547 VAL B O   1 
ATOM   3643 C  CB  . VAL A 1 547 ? 141.410 95.876  138.072 1.00 64.09  ? 547 VAL B CB  1 
ATOM   3644 C  CG1 . VAL A 1 547 ? 141.590 95.973  136.567 1.00 64.09  ? 547 VAL B CG1 1 
ATOM   3645 C  CG2 . VAL A 1 547 ? 141.449 97.255  138.707 1.00 64.09  ? 547 VAL B CG2 1 
ATOM   3646 N  N   . ILE A 1 548 ? 140.542 92.764  138.441 1.00 63.67  ? 548 ILE B N   1 
ATOM   3647 C  CA  . ILE A 1 548 ? 140.536 91.419  137.870 1.00 63.67  ? 548 ILE B CA  1 
ATOM   3648 C  C   . ILE A 1 548 ? 139.107 90.921  137.688 1.00 63.67  ? 548 ILE B C   1 
ATOM   3649 O  O   . ILE A 1 548 ? 138.745 90.395  136.629 1.00 63.67  ? 548 ILE B O   1 
ATOM   3650 C  CB  . ILE A 1 548 ? 141.359 90.460  138.747 1.00 63.67  ? 548 ILE B CB  1 
ATOM   3651 C  CG1 . ILE A 1 548 ? 142.702 91.092  139.115 1.00 63.67  ? 548 ILE B CG1 1 
ATOM   3652 C  CG2 . ILE A 1 548 ? 141.563 89.134  138.033 1.00 63.67  ? 548 ILE B CG2 1 
ATOM   3653 C  CD1 . ILE A 1 548 ? 143.569 91.429  137.922 1.00 63.67  ? 548 ILE B CD1 1 
ATOM   3654 N  N   . ASP A 1 549 ? 138.273 91.080  138.719 1.00 66.07  ? 549 ASP B N   1 
ATOM   3655 C  CA  . ASP A 1 549 ? 136.884 90.637  138.622 1.00 66.07  ? 549 ASP B CA  1 
ATOM   3656 C  C   . ASP A 1 549 ? 136.124 91.432  137.571 1.00 66.07  ? 549 ASP B C   1 
ATOM   3657 O  O   . ASP A 1 549 ? 135.317 90.873  136.815 1.00 66.07  ? 549 ASP B O   1 
ATOM   3658 C  CB  . ASP A 1 549 ? 136.198 90.759  139.982 1.00 66.07  ? 549 ASP B CB  1 
ATOM   3659 C  CG  . ASP A 1 549 ? 136.639 89.685  140.956 1.00 66.07  ? 549 ASP B CG  1 
ATOM   3660 O  OD1 . ASP A 1 549 ? 136.875 88.541  140.515 1.00 66.07  ? 549 ASP B OD1 1 
ATOM   3661 O  OD2 . ASP A 1 549 ? 136.752 89.986  142.163 1.00 66.07  ? 549 ASP B OD2 1 
ATOM   3662 N  N   . MET A 1 550 ? 136.362 92.743  137.515 1.00 58.56  ? 550 MET B N   1 
ATOM   3663 C  CA  . MET A 1 550 ? 135.688 93.574  136.526 1.00 58.56  ? 550 MET B CA  1 
ATOM   3664 C  C   . MET A 1 550 ? 136.048 93.139  135.113 1.00 58.56  ? 550 MET B C   1 
ATOM   3665 O  O   . MET A 1 550 ? 135.173 93.032  134.249 1.00 58.56  ? 550 MET B O   1 
ATOM   3666 C  CB  . MET A 1 550 ? 136.049 95.041  136.747 1.00 58.56  ? 550 MET B CB  1 
ATOM   3667 C  CG  . MET A 1 550 ? 135.373 95.996  135.793 1.00 58.56  ? 550 MET B CG  1 
ATOM   3668 S  SD  . MET A 1 550 ? 134.986 97.554  136.604 1.00 58.56  ? 550 MET B SD  1 
ATOM   3669 C  CE  . MET A 1 550 ? 133.775 98.219  135.474 1.00 58.56  ? 550 MET B CE  1 
ATOM   3670 N  N   . VAL A 1 551 ? 137.330 92.863  134.868 1.00 57.94  ? 551 VAL B N   1 
ATOM   3671 C  CA  . VAL A 1 551 ? 137.759 92.403  133.551 1.00 57.94  ? 551 VAL B CA  1 
ATOM   3672 C  C   . VAL A 1 551 ? 137.165 91.035  133.239 1.00 57.94  ? 551 VAL B C   1 
ATOM   3673 O  O   . VAL A 1 551 ? 136.729 90.776  132.110 1.00 57.94  ? 551 VAL B O   1 
ATOM   3674 C  CB  . VAL A 1 551 ? 139.296 92.391  133.469 1.00 57.94  ? 551 VAL B CB  1 
ATOM   3675 C  CG1 . VAL A 1 551 ? 139.764 91.610  132.255 1.00 57.94  ? 551 VAL B CG1 1 
ATOM   3676 C  CG2 . VAL A 1 551 ? 139.832 93.811  133.427 1.00 57.94  ? 551 VAL B CG2 1 
ATOM   3677 N  N   . LYS A 1 552 ? 137.134 90.138  134.229 1.00 57.68  ? 552 LYS B N   1 
ATOM   3678 C  CA  . LYS A 1 552 ? 136.586 88.805  134.000 1.00 57.68  ? 552 LYS B CA  1 
ATOM   3679 C  C   . LYS A 1 552 ? 135.117 88.867  133.606 1.00 57.68  ? 552 LYS B C   1 
ATOM   3680 O  O   . LYS A 1 552 ? 134.682 88.160  132.691 1.00 57.68  ? 552 LYS B O   1 
ATOM   3681 C  CB  . LYS A 1 552 ? 136.766 87.940  135.245 1.00 57.68  ? 552 LYS B CB  1 
ATOM   3682 C  CG  . LYS A 1 552 ? 138.177 87.421  135.448 1.00 57.68  ? 552 LYS B CG  1 
ATOM   3683 C  CD  . LYS A 1 552 ? 138.218 86.366  136.539 1.00 57.68  ? 552 LYS B CD  1 
ATOM   3684 C  CE  . LYS A 1 552 ? 137.473 86.831  137.780 1.00 57.68  ? 552 LYS B CE  1 
ATOM   3685 N  NZ  . LYS A 1 552 ? 137.387 85.765  138.815 1.00 57.68  ? 552 LYS B NZ  1 
ATOM   3686 N  N   . ALA A 1 553 ? 134.333 89.703  134.289 1.00 53.98  ? 553 ALA B N   1 
ATOM   3687 C  CA  . ALA A 1 553 ? 132.923 89.832  133.930 1.00 53.98  ? 553 ALA B CA  1 
ATOM   3688 C  C   . ALA A 1 553 ? 132.756 90.546  132.593 1.00 53.98  ? 553 ALA B C   1 
ATOM   3689 O  O   . ALA A 1 553 ? 131.918 90.155  131.766 1.00 53.98  ? 553 ALA B O   1 
ATOM   3690 C  CB  . ALA A 1 553 ? 132.166 90.570  135.031 1.00 53.98  ? 553 ALA B CB  1 
ATOM   3691 N  N   . GLY A 1 554 ? 133.554 91.588  132.358 1.00 50.61  ? 554 GLY B N   1 
ATOM   3692 C  CA  . GLY A 1 554 ? 133.387 92.380  131.159 1.00 50.61  ? 554 GLY B CA  1 
ATOM   3693 C  C   . GLY A 1 554 ? 133.798 91.665  129.894 1.00 50.61  ? 554 GLY B C   1 
ATOM   3694 O  O   . GLY A 1 554 ? 133.267 91.956  128.824 1.00 50.61  ? 554 GLY B O   1 
ATOM   3695 N  N   . LEU A 1 555 ? 134.740 90.726  129.987 1.00 50.28  ? 555 LEU B N   1 
ATOM   3696 C  CA  . LEU A 1 555 ? 135.087 89.934  128.811 1.00 50.28  ? 555 LEU B CA  1 
ATOM   3697 C  C   . LEU A 1 555 ? 133.879 89.149  128.317 1.00 50.28  ? 555 LEU B C   1 
ATOM   3698 O  O   . LEU A 1 555 ? 133.547 89.176  127.125 1.00 50.28  ? 555 LEU B O   1 
ATOM   3699 C  CB  . LEU A 1 555 ? 136.250 88.997  129.130 1.00 50.28  ? 555 LEU B CB  1 
ATOM   3700 C  CG  . LEU A 1 555 ? 137.643 89.595  128.948 1.00 50.28  ? 555 LEU B CG  1 
ATOM   3701 C  CD1 . LEU A 1 555 ? 138.700 88.680  129.542 1.00 50.28  ? 555 LEU B CD1 1 
ATOM   3702 C  CD2 . LEU A 1 555 ? 137.917 89.856  127.479 1.00 50.28  ? 555 LEU B CD2 1 
ATOM   3703 N  N   . GLY A 1 556 ? 133.190 88.464  129.231 1.00 49.31  ? 556 GLY B N   1 
ATOM   3704 C  CA  . GLY A 1 556 ? 131.993 87.738  128.847 1.00 49.31  ? 556 GLY B CA  1 
ATOM   3705 C  C   . GLY A 1 556 ? 130.884 88.653  128.369 1.00 49.31  ? 556 GLY B C   1 
ATOM   3706 O  O   . GLY A 1 556 ? 130.202 88.354  127.384 1.00 49.31  ? 556 GLY B O   1 
ATOM   3707 N  N   . VAL A 1 557 ? 130.691 89.784  129.053 1.00 48.11  ? 557 VAL B N   1 
ATOM   3708 C  CA  . VAL A 1 557 ? 129.636 90.710  128.643 1.00 48.11  ? 557 VAL B CA  1 
ATOM   3709 C  C   . VAL A 1 557 ? 129.910 91.255  127.246 1.00 48.11  ? 557 VAL B C   1 
ATOM   3710 O  O   . VAL A 1 557 ? 129.005 91.338  126.408 1.00 48.11  ? 557 VAL B O   1 
ATOM   3711 C  CB  . VAL A 1 557 ? 129.481 91.841  129.673 1.00 48.11  ? 557 VAL B CB  1 
ATOM   3712 C  CG1 . VAL A 1 557 ? 128.582 92.932  129.122 1.00 48.11  ? 557 VAL B CG1 1 
ATOM   3713 C  CG2 . VAL A 1 557 ? 128.912 91.289  130.963 1.00 48.11  ? 557 VAL B CG2 1 
ATOM   3714 N  N   . ASN A 1 558 ? 131.161 91.628  126.970 1.00 47.35  ? 558 ASN B N   1 
ATOM   3715 C  CA  . ASN A 1 558 ? 131.521 92.161  125.662 1.00 47.35  ? 558 ASN B CA  1 
ATOM   3716 C  C   . ASN A 1 558 ? 131.403 91.100  124.577 1.00 47.35  ? 558 ASN B C   1 
ATOM   3717 O  O   . ASN A 1 558 ? 130.963 91.397  123.460 1.00 47.35  ? 558 ASN B O   1 
ATOM   3718 C  CB  . ASN A 1 558 ? 132.937 92.730  125.706 1.00 47.35  ? 558 ASN B CB  1 
ATOM   3719 C  CG  . ASN A 1 558 ? 133.152 93.827  124.694 1.00 47.35  ? 558 ASN B CG  1 
ATOM   3720 O  OD1 . ASN A 1 558 ? 132.900 93.645  123.505 1.00 47.35  ? 558 ASN B OD1 1 
ATOM   3721 N  ND2 . ASN A 1 558 ? 133.622 94.977  125.158 1.00 47.35  ? 558 ASN B ND2 1 
ATOM   3722 N  N   . ILE A 1 559 ? 131.796 89.859  124.878 1.00 46.08  ? 559 ILE B N   1 
ATOM   3723 C  CA  . ILE A 1 559 ? 131.641 88.784  123.903 1.00 46.08  ? 559 ILE B CA  1 
ATOM   3724 C  C   . ILE A 1 559 ? 130.170 88.579  123.569 1.00 46.08  ? 559 ILE B C   1 
ATOM   3725 O  O   . ILE A 1 559 ? 129.794 88.455  122.396 1.00 46.08  ? 559 ILE B O   1 
ATOM   3726 C  CB  . ILE A 1 559 ? 132.292 87.490  124.424 1.00 46.08  ? 559 ILE B CB  1 
ATOM   3727 C  CG1 . ILE A 1 559 ? 133.814 87.574  124.306 1.00 46.08  ? 559 ILE B CG1 1 
ATOM   3728 C  CG2 . ILE A 1 559 ? 131.765 86.283  123.666 1.00 46.08  ? 559 ILE B CG2 1 
ATOM   3729 C  CD1 . ILE A 1 559 ? 134.539 86.411  124.940 1.00 46.08  ? 559 ILE B CD1 1 
ATOM   3730 N  N   . VAL A 1 560 ? 129.314 88.557  124.593 1.00 47.03  ? 560 VAL B N   1 
ATOM   3731 C  CA  . VAL A 1 560 ? 127.883 88.381  124.360 1.00 47.03  ? 560 VAL B CA  1 
ATOM   3732 C  C   . VAL A 1 560 ? 127.329 89.540  123.541 1.00 47.03  ? 560 VAL B C   1 
ATOM   3733 O  O   . VAL A 1 560 ? 126.543 89.339  122.607 1.00 47.03  ? 560 VAL B O   1 
ATOM   3734 C  CB  . VAL A 1 560 ? 127.141 88.226  125.700 1.00 47.03  ? 560 VAL B CB  1 
ATOM   3735 C  CG1 . VAL A 1 560 ? 125.661 88.504  125.523 1.00 47.03  ? 560 VAL B CG1 1 
ATOM   3736 C  CG2 . VAL A 1 560 ? 127.359 86.833  126.266 1.00 47.03  ? 560 VAL B CG2 1 
ATOM   3737 N  N   . GLY A 1 561 ? 127.729 90.768  123.874 1.00 46.98  ? 561 GLY B N   1 
ATOM   3738 C  CA  . GLY A 1 561 ? 127.238 91.919  123.137 1.00 46.98  ? 561 GLY B CA  1 
ATOM   3739 C  C   . GLY A 1 561 ? 127.652 91.903  121.678 1.00 46.98  ? 561 GLY B C   1 
ATOM   3740 O  O   . GLY A 1 561 ? 126.841 92.179  120.791 1.00 46.98  ? 561 GLY B O   1 
ATOM   3741 N  N   . VAL A 1 562 ? 128.918 91.577  121.410 1.00 46.57  ? 562 VAL B N   1 
ATOM   3742 C  CA  . VAL A 1 562 ? 129.394 91.512  120.031 1.00 46.57  ? 562 VAL B CA  1 
ATOM   3743 C  C   . VAL A 1 562 ? 128.662 90.418  119.266 1.00 46.57  ? 562 VAL B C   1 
ATOM   3744 O  O   . VAL A 1 562 ? 128.256 90.612  118.113 1.00 46.57  ? 562 VAL B O   1 
ATOM   3745 C  CB  . VAL A 1 562 ? 130.920 91.308  120.004 1.00 46.57  ? 562 VAL B CB  1 
ATOM   3746 C  CG1 . VAL A 1 562 ? 131.380 90.904  118.617 1.00 46.57  ? 562 VAL B CG1 1 
ATOM   3747 C  CG2 . VAL A 1 562 ? 131.626 92.575  120.450 1.00 46.57  ? 562 VAL B CG2 1 
ATOM   3748 N  N   . ALA A 1 563 ? 128.477 89.253  119.894 1.00 48.28  ? 563 ALA B N   1 
ATOM   3749 C  CA  . ALA A 1 563 ? 127.766 88.167  119.229 1.00 48.28  ? 563 ALA B CA  1 
ATOM   3750 C  C   . ALA A 1 563 ? 126.334 88.565  118.898 1.00 48.28  ? 563 ALA B C   1 
ATOM   3751 O  O   . ALA A 1 563 ? 125.845 88.292  117.795 1.00 48.28  ? 563 ALA B O   1 
ATOM   3752 C  CB  . ALA A 1 563 ? 127.785 86.913  120.101 1.00 48.28  ? 563 ALA B CB  1 
ATOM   3753 N  N   . VAL A 1 564 ? 125.647 89.221  119.835 1.00 49.03  ? 564 VAL B N   1 
ATOM   3754 C  CA  . VAL A 1 564 ? 124.262 89.614  119.595 1.00 49.03  ? 564 VAL B CA  1 
ATOM   3755 C  C   . VAL A 1 564 ? 124.185 90.685  118.514 1.00 49.03  ? 564 VAL B C   1 
ATOM   3756 O  O   . VAL A 1 564 ? 123.269 90.680  117.685 1.00 49.03  ? 564 VAL B O   1 
ATOM   3757 C  CB  . VAL A 1 564 ? 123.600 90.076  120.904 1.00 49.03  ? 564 VAL B CB  1 
ATOM   3758 C  CG1 . VAL A 1 564 ? 122.246 90.703  120.625 1.00 49.03  ? 564 VAL B CG1 1 
ATOM   3759 C  CG2 . VAL A 1 564 ? 123.452 88.903  121.855 1.00 49.03  ? 564 VAL B CG2 1 
ATOM   3760 N  N   . VAL A 1 565 ? 125.142 91.616  118.496 1.00 50.34  ? 565 VAL B N   1 
ATOM   3761 C  CA  . VAL A 1 565 ? 125.146 92.645  117.459 1.00 50.34  ? 565 VAL B CA  1 
ATOM   3762 C  C   . VAL A 1 565 ? 125.355 92.018  116.086 1.00 50.34  ? 565 VAL B C   1 
ATOM   3763 O  O   . VAL A 1 565 ? 124.688 92.387  115.111 1.00 50.34  ? 565 VAL B O   1 
ATOM   3764 C  CB  . VAL A 1 565 ? 126.210 93.714  117.765 1.00 50.34  ? 565 VAL B CB  1 
ATOM   3765 C  CG1 . VAL A 1 565 ? 126.469 94.573  116.540 1.00 50.34  ? 565 VAL B CG1 1 
ATOM   3766 C  CG2 . VAL A 1 565 ? 125.765 94.579  118.929 1.00 50.34  ? 565 VAL B CG2 1 
ATOM   3767 N  N   . MET A 1 566 ? 126.282 91.062  115.985 1.00 55.96  ? 566 MET B N   1 
ATOM   3768 C  CA  . MET A 1 566 ? 126.499 90.388  114.708 1.00 55.96  ? 566 MET B CA  1 
ATOM   3769 C  C   . MET A 1 566 ? 125.267 89.596  114.287 1.00 55.96  ? 566 MET B C   1 
ATOM   3770 O  O   . MET A 1 566 ? 124.897 89.590  113.106 1.00 55.96  ? 566 MET B O   1 
ATOM   3771 C  CB  . MET A 1 566 ? 127.721 89.477  114.793 1.00 55.96  ? 566 MET B CB  1 
ATOM   3772 C  CG  . MET A 1 566 ? 129.022 90.222  115.011 1.00 55.96  ? 566 MET B CG  1 
ATOM   3773 S  SD  . MET A 1 566 ? 129.436 91.309  113.639 1.00 55.96  ? 566 MET B SD  1 
ATOM   3774 C  CE  . MET A 1 566 ? 130.845 92.174  114.322 1.00 55.96  ? 566 MET B CE  1 
ATOM   3775 N  N   . LEU A 1 567 ? 124.620 88.924  115.242 1.00 53.73  ? 567 LEU B N   1 
ATOM   3776 C  CA  . LEU A 1 567 ? 123.400 88.187  114.935 1.00 53.73  ? 567 LEU B CA  1 
ATOM   3777 C  C   . LEU A 1 567 ? 122.308 89.121  114.433 1.00 53.73  ? 567 LEU B C   1 
ATOM   3778 O  O   . LEU A 1 567 ? 121.581 88.788  113.492 1.00 53.73  ? 567 LEU B O   1 
ATOM   3779 C  CB  . LEU A 1 567 ? 122.931 87.423  116.173 1.00 53.73  ? 567 LEU B CB  1 
ATOM   3780 C  CG  . LEU A 1 567 ? 121.896 86.313  115.995 1.00 53.73  ? 567 LEU B CG  1 
ATOM   3781 C  CD1 . LEU A 1 567 ? 122.185 85.176  116.959 1.00 53.73  ? 567 LEU B CD1 1 
ATOM   3782 C  CD2 . LEU A 1 567 ? 120.488 86.844  116.208 1.00 53.73  ? 567 LEU B CD2 1 
ATOM   3783 N  N   . GLY A 1 568 ? 122.176 90.294  115.053 1.00 58.65  ? 568 GLY B N   1 
ATOM   3784 C  CA  . GLY A 1 568 ? 121.186 91.255  114.599 1.00 58.65  ? 568 GLY B CA  1 
ATOM   3785 C  C   . GLY A 1 568 ? 121.493 91.802  113.219 1.00 58.65  ? 568 GLY B C   1 
ATOM   3786 O  O   . GLY A 1 568 ? 120.590 91.975  112.397 1.00 58.65  ? 568 GLY B O   1 
ATOM   3787 N  N   . ILE A 1 569 ? 122.769 92.084  112.947 1.00 58.92  ? 569 ILE B N   1 
ATOM   3788 C  CA  . ILE A 1 569 ? 123.156 92.555  111.620 1.00 58.92  ? 569 ILE B CA  1 
ATOM   3789 C  C   . ILE A 1 569 ? 122.832 91.503  110.569 1.00 58.92  ? 569 ILE B C   1 
ATOM   3790 O  O   . ILE A 1 569 ? 122.316 91.819  109.491 1.00 58.92  ? 569 ILE B O   1 
ATOM   3791 C  CB  . ILE A 1 569 ? 124.648 92.938  111.599 1.00 58.92  ? 569 ILE B CB  1 
ATOM   3792 C  CG1 . ILE A 1 569 ? 124.861 94.281  112.294 1.00 58.92  ? 569 ILE B CG1 1 
ATOM   3793 C  CG2 . ILE A 1 569 ? 125.169 92.999  110.176 1.00 58.92  ? 569 ILE B CG2 1 
ATOM   3794 C  CD1 . ILE A 1 569 ? 124.226 95.441  111.567 1.00 58.92  ? 569 ILE B CD1 1 
ATOM   3795 N  N   . CYS A 1 570 ? 123.116 90.236  110.868 1.00 60.56  ? 570 CYS B N   1 
ATOM   3796 C  CA  . CYS A 1 570 ? 122.875 89.187  109.885 1.00 60.56  ? 570 CYS B CA  1 
ATOM   3797 C  C   . CYS A 1 570 ? 121.390 88.874  109.724 1.00 60.56  ? 570 CYS B C   1 
ATOM   3798 O  O   . CYS A 1 570 ? 120.953 88.522  108.623 1.00 60.56  ? 570 CYS B O   1 
ATOM   3799 C  CB  . CYS A 1 570 ? 123.640 87.922  110.272 1.00 60.56  ? 570 CYS B CB  1 
ATOM   3800 S  SG  . CYS A 1 570 ? 123.520 86.581  109.068 1.00 60.56  ? 570 CYS B SG  1 
ATOM   3801 N  N   . THR A 1 571 ? 120.600 88.994  110.793 1.00 61.41  ? 571 THR B N   1 
ATOM   3802 C  CA  . THR A 1 571 ? 119.253 88.432  110.815 1.00 61.41  ? 571 THR B CA  1 
ATOM   3803 C  C   . THR A 1 571 ? 118.162 89.432  110.438 1.00 61.41  ? 571 THR B C   1 
ATOM   3804 O  O   . THR A 1 571 ? 117.479 89.245  109.428 1.00 61.41  ? 571 THR B O   1 
ATOM   3805 C  CB  . THR A 1 571 ? 118.961 87.842  112.201 1.00 61.41  ? 571 THR B CB  1 
ATOM   3806 O  OG1 . THR A 1 571 ? 119.908 86.806  112.490 1.00 61.41  ? 571 THR B OG1 1 
ATOM   3807 C  CG2 . THR A 1 571 ? 117.558 87.263  112.246 1.00 61.41  ? 571 THR B CG2 1 
ATOM   3808 N  N   . TRP A 1 572 ? 117.983 90.497  111.225 1.00 60.46  ? 572 TRP B N   1 
ATOM   3809 C  CA  . TRP A 1 572 ? 116.775 91.304  111.113 1.00 60.46  ? 572 TRP B CA  1 
ATOM   3810 C  C   . TRP A 1 572 ? 116.998 92.772  110.781 1.00 60.46  ? 572 TRP B C   1 
ATOM   3811 O  O   . TRP A 1 572 ? 116.038 93.439  110.383 1.00 60.46  ? 572 TRP B O   1 
ATOM   3812 C  CB  . TRP A 1 572 ? 115.944 91.213  112.406 1.00 60.46  ? 572 TRP B CB  1 
ATOM   3813 C  CG  . TRP A 1 572 ? 116.500 91.965  113.583 1.00 60.46  ? 572 TRP B CG  1 
ATOM   3814 C  CD1 . TRP A 1 572 ? 116.385 93.302  113.833 1.00 60.46  ? 572 TRP B CD1 1 
ATOM   3815 C  CD2 . TRP A 1 572 ? 117.231 91.415  114.685 1.00 60.46  ? 572 TRP B CD2 1 
ATOM   3816 N  NE1 . TRP A 1 572 ? 117.011 93.620  115.013 1.00 60.46  ? 572 TRP B NE1 1 
ATOM   3817 C  CE2 . TRP A 1 572 ? 117.538 92.479  115.556 1.00 60.46  ? 572 TRP B CE2 1 
ATOM   3818 C  CE3 . TRP A 1 572 ? 117.663 90.128  115.016 1.00 60.46  ? 572 TRP B CE3 1 
ATOM   3819 C  CZ2 . TRP A 1 572 ? 118.256 92.295  116.733 1.00 60.46  ? 572 TRP B CZ2 1 
ATOM   3820 C  CZ3 . TRP A 1 572 ? 118.374 89.948  116.186 1.00 60.46  ? 572 TRP B CZ3 1 
ATOM   3821 C  CH2 . TRP A 1 572 ? 118.664 91.025  117.030 1.00 60.46  ? 572 TRP B CH2 1 
ATOM   3822 N  N   . ILE A 1 573 ? 118.211 93.300  110.940 1.00 62.43  ? 573 ILE B N   1 
ATOM   3823 C  CA  . ILE A 1 573 ? 118.444 94.700  110.598 1.00 62.43  ? 573 ILE B CA  1 
ATOM   3824 C  C   . ILE A 1 573 ? 118.392 94.901  109.087 1.00 62.43  ? 573 ILE B C   1 
ATOM   3825 O  O   . ILE A 1 573 ? 117.879 95.916  108.598 1.00 62.43  ? 573 ILE B O   1 
ATOM   3826 C  CB  . ILE A 1 573 ? 119.776 95.182  111.198 1.00 62.43  ? 573 ILE B CB  1 
ATOM   3827 C  CG1 . ILE A 1 573 ? 119.742 95.057  112.721 1.00 62.43  ? 573 ILE B CG1 1 
ATOM   3828 C  CG2 . ILE A 1 573 ? 120.057 96.619  110.797 1.00 62.43  ? 573 ILE B CG2 1 
ATOM   3829 C  CD1 . ILE A 1 573 ? 120.941 95.660  113.411 1.00 62.43  ? 573 ILE B CD1 1 
ATOM   3830 N  N   . VAL A 1 574 ? 118.923 93.940  108.326 1.00 65.24  ? 574 VAL B N   1 
ATOM   3831 C  CA  . VAL A 1 574 ? 118.972 94.087  106.870 1.00 65.24  ? 574 VAL B CA  1 
ATOM   3832 C  C   . VAL A 1 574 ? 117.589 94.237  106.246 1.00 65.24  ? 574 VAL B C   1 
ATOM   3833 O  O   . VAL A 1 574 ? 117.406 95.147  105.421 1.00 65.24  ? 574 VAL B O   1 
ATOM   3834 C  CB  . VAL A 1 574 ? 119.773 92.927  106.249 1.00 65.24  ? 574 VAL B CB  1 
ATOM   3835 C  CG1 . VAL A 1 574 ? 119.735 93.016  104.736 1.00 65.24  ? 574 VAL B CG1 1 
ATOM   3836 C  CG2 . VAL A 1 574 ? 121.202 92.951  106.746 1.00 65.24  ? 574 VAL B CG2 1 
ATOM   3837 N  N   . PRO A 1 575 ? 116.590 93.400  106.565 1.00 66.88  ? 575 PRO B N   1 
ATOM   3838 C  CA  . PRO A 1 575 ? 115.281 93.574  105.910 1.00 66.88  ? 575 PRO B CA  1 
ATOM   3839 C  C   . PRO A 1 575 ? 114.661 94.942  106.133 1.00 66.88  ? 575 PRO B C   1 
ATOM   3840 O  O   . PRO A 1 575 ? 114.001 95.470  105.230 1.00 66.88  ? 575 PRO B O   1 
ATOM   3841 C  CB  . PRO A 1 575 ? 114.431 92.459  106.534 1.00 66.88  ? 575 PRO B CB  1 
ATOM   3842 C  CG  . PRO A 1 575 ? 115.409 91.424  106.925 1.00 66.88  ? 575 PRO B CG  1 
ATOM   3843 C  CD  . PRO A 1 575 ? 116.612 92.181  107.396 1.00 66.88  ? 575 PRO B CD  1 
ATOM   3844 N  N   . MET A 1 576 ? 114.854 95.537  107.309 1.00 63.59  ? 576 MET B N   1 
ATOM   3845 C  CA  . MET A 1 576 ? 114.248 96.831  107.593 1.00 63.59  ? 576 MET B CA  1 
ATOM   3846 C  C   . MET A 1 576 ? 115.124 98.006  107.182 1.00 63.59  ? 576 MET B C   1 
ATOM   3847 O  O   . MET A 1 576 ? 114.638 99.141  107.143 1.00 63.59  ? 576 MET B O   1 
ATOM   3848 C  CB  . MET A 1 576 ? 113.910 96.944  109.082 1.00 63.59  ? 576 MET B CB  1 
ATOM   3849 C  CG  . MET A 1 576 ? 115.113 97.111  109.988 1.00 63.59  ? 576 MET B CG  1 
ATOM   3850 S  SD  . MET A 1 576 ? 114.649 97.114  111.728 1.00 63.59  ? 576 MET B SD  1 
ATOM   3851 C  CE  . MET A 1 576 ? 113.855 95.517  111.871 1.00 63.59  ? 576 MET B CE  1 
ATOM   3852 N  N   . PHE A 1 577 ? 116.402 97.772  106.877 1.00 65.06  ? 577 PHE B N   1 
ATOM   3853 C  CA  . PHE A 1 577 ? 117.286 98.851  106.459 1.00 65.06  ? 577 PHE B CA  1 
ATOM   3854 C  C   . PHE A 1 577 ? 117.822 98.701  105.043 1.00 65.06  ? 577 PHE B C   1 
ATOM   3855 O  O   . PHE A 1 577 ? 118.468 99.633  104.549 1.00 65.06  ? 577 PHE B O   1 
ATOM   3856 C  CB  . PHE A 1 577 ? 118.467 98.979  107.432 1.00 65.06  ? 577 PHE B CB  1 
ATOM   3857 C  CG  . PHE A 1 577 ? 118.230 99.959  108.543 1.00 65.06  ? 577 PHE B CG  1 
ATOM   3858 C  CD1 . PHE A 1 577 ? 118.135 101.313 108.280 1.00 65.06  ? 577 PHE B CD1 1 
ATOM   3859 C  CD2 . PHE A 1 577 ? 118.102 99.526  109.851 1.00 65.06  ? 577 PHE B CD2 1 
ATOM   3860 C  CE1 . PHE A 1 577 ? 117.918 102.218 109.299 1.00 65.06  ? 577 PHE B CE1 1 
ATOM   3861 C  CE2 . PHE A 1 577 ? 117.885 100.426 110.875 1.00 65.06  ? 577 PHE B CE2 1 
ATOM   3862 C  CZ  . PHE A 1 577 ? 117.792 101.773 110.598 1.00 65.06  ? 577 PHE B CZ  1 
ATOM   3863 N  N   . ASP A 1 578 ? 117.573 97.571  104.379 1.00 67.60  ? 578 ASP B N   1 
ATOM   3864 C  CA  . ASP A 1 578 ? 118.076 97.312  103.029 1.00 67.60  ? 578 ASP B CA  1 
ATOM   3865 C  C   . ASP A 1 578 ? 119.595 97.464  102.972 1.00 67.60  ? 578 ASP B C   1 
ATOM   3866 O  O   . ASP A 1 578 ? 120.147 98.181  102.134 1.00 67.60  ? 578 ASP B O   1 
ATOM   3867 C  CB  . ASP A 1 578 ? 117.394 98.219  102.004 1.00 67.60  ? 578 ASP B CB  1 
ATOM   3868 C  CG  . ASP A 1 578 ? 115.998 97.749  101.649 1.00 67.60  ? 578 ASP B CG  1 
ATOM   3869 O  OD1 . ASP A 1 578 ? 115.355 97.099  102.500 1.00 67.60  ? 578 ASP B OD1 1 
ATOM   3870 O  OD2 . ASP A 1 578 ? 115.543 98.031  100.521 1.00 67.60  ? 578 ASP B OD2 1 
ATOM   3871 N  N   . LEU A 1 579 ? 120.276 96.775  103.891 1.00 65.83  ? 579 LEU B N   1 
ATOM   3872 C  CA  . LEU A 1 579 ? 121.727 96.895  103.987 1.00 65.83  ? 579 LEU B CA  1 
ATOM   3873 C  C   . LEU A 1 579 ? 122.434 96.254  102.799 1.00 65.83  ? 579 LEU B C   1 
ATOM   3874 O  O   . LEU A 1 579 ? 123.521 96.699  102.414 1.00 65.83  ? 579 LEU B O   1 
ATOM   3875 C  CB  . LEU A 1 579 ? 122.218 96.272  105.293 1.00 65.83  ? 579 LEU B CB  1 
ATOM   3876 C  CG  . LEU A 1 579 ? 121.811 96.997  106.578 1.00 65.83  ? 579 LEU B CG  1 
ATOM   3877 C  CD1 . LEU A 1 579 ? 122.354 96.281  107.800 1.00 65.83  ? 579 LEU B CD1 1 
ATOM   3878 C  CD2 . LEU A 1 579 ? 122.283 98.436  106.550 1.00 65.83  ? 579 LEU B CD2 1 
ATOM   3879 N  N   . TYR A 1 580 ? 121.845 95.211  102.211 1.00 68.71  ? 580 TYR B N   1 
ATOM   3880 C  CA  . TYR A 1 580 ? 122.512 94.509  101.120 1.00 68.71  ? 580 TYR B CA  1 
ATOM   3881 C  C   . TYR A 1 580 ? 122.528 95.340  99.842  1.00 68.71  ? 580 TYR B C   1 
ATOM   3882 O  O   . TYR A 1 580 ? 123.444 95.209  99.023  1.00 68.71  ? 580 TYR B O   1 
ATOM   3883 C  CB  . TYR A 1 580 ? 121.840 93.159  100.876 1.00 68.71  ? 580 TYR B CB  1 
ATOM   3884 C  CG  . TYR A 1 580 ? 122.105 92.151  101.969 1.00 68.71  ? 580 TYR B CG  1 
ATOM   3885 C  CD1 . TYR A 1 580 ? 123.231 92.253  102.774 1.00 68.71  ? 580 TYR B CD1 1 
ATOM   3886 C  CD2 . TYR A 1 580 ? 121.231 91.097  102.197 1.00 68.71  ? 580 TYR B CD2 1 
ATOM   3887 C  CE1 . TYR A 1 580 ? 123.479 91.336  103.776 1.00 68.71  ? 580 TYR B CE1 1 
ATOM   3888 C  CE2 . TYR A 1 580 ? 121.470 90.175  103.198 1.00 68.71  ? 580 TYR B CE2 1 
ATOM   3889 C  CZ  . TYR A 1 580 ? 122.596 90.300  103.984 1.00 68.71  ? 580 TYR B CZ  1 
ATOM   3890 O  OH  . TYR A 1 580 ? 122.842 89.385  104.981 1.00 68.71  ? 580 TYR B OH  1 
ATOM   3891 N  N   . THR A 1 581 ? 121.528 96.195  99.652  1.00 70.25  ? 581 THR B N   1 
ATOM   3892 C  CA  . THR A 1 581 ? 121.418 96.994  98.440  1.00 70.25  ? 581 THR B CA  1 
ATOM   3893 C  C   . THR A 1 581 ? 122.017 98.376  98.667  1.00 70.25  ? 581 THR B C   1 
ATOM   3894 O  O   . THR A 1 581 ? 121.716 99.034  99.667  1.00 70.25  ? 581 THR B O   1 
ATOM   3895 C  CB  . THR A 1 581 ? 119.956 97.116  98.006  1.00 70.25  ? 581 THR B CB  1 
ATOM   3896 O  OG1 . THR A 1 581 ? 119.424 95.812  97.749  1.00 70.25  ? 581 THR B OG1 1 
ATOM   3897 C  CG2 . THR A 1 581 ? 119.842 97.959  96.746  1.00 70.25  ? 581 THR B CG2 1 
ATOM   3898 N  N   . TYR A 1 582 ? 122.867 98.806  97.739  1.00 73.31  ? 582 TYR B N   1 
ATOM   3899 C  CA  . TYR A 1 582 ? 123.463 100.128 97.831  1.00 73.31  ? 582 TYR B CA  1 
ATOM   3900 C  C   . TYR A 1 582 ? 122.374 101.195 97.750  1.00 73.31  ? 582 TYR B C   1 
ATOM   3901 O  O   . TYR A 1 582 ? 121.443 101.072 96.946  1.00 73.31  ? 582 TYR B O   1 
ATOM   3902 C  CB  . TYR A 1 582 ? 124.483 100.330 96.709  1.00 73.31  ? 582 TYR B CB  1 
ATOM   3903 C  CG  . TYR A 1 582 ? 125.495 101.422 96.972  1.00 73.31  ? 582 TYR B CG  1 
ATOM   3904 C  CD1 . TYR A 1 582 ? 126.554 101.220 97.845  1.00 73.31  ? 582 TYR B CD1 1 
ATOM   3905 C  CD2 . TYR A 1 582 ? 125.393 102.655 96.343  1.00 73.31  ? 582 TYR B CD2 1 
ATOM   3906 C  CE1 . TYR A 1 582 ? 127.481 102.215 98.085  1.00 73.31  ? 582 TYR B CE1 1 
ATOM   3907 C  CE2 . TYR A 1 582 ? 126.315 103.655 96.578  1.00 73.31  ? 582 TYR B CE2 1 
ATOM   3908 C  CZ  . TYR A 1 582 ? 127.356 103.429 97.449  1.00 73.31  ? 582 TYR B CZ  1 
ATOM   3909 O  OH  . TYR A 1 582 ? 128.276 104.423 97.685  1.00 73.31  ? 582 TYR B OH  1 
ATOM   3910 N  N   . PRO A 1 583 ? 122.453 102.247 98.559  1.00 77.38  ? 583 PRO B N   1 
ATOM   3911 C  CA  . PRO A 1 583 ? 121.392 103.254 98.583  1.00 77.38  ? 583 PRO B CA  1 
ATOM   3912 C  C   . PRO A 1 583 ? 121.614 104.367 97.569  1.00 77.38  ? 583 PRO B C   1 
ATOM   3913 O  O   . PRO A 1 583 ? 122.708 104.565 97.039  1.00 77.38  ? 583 PRO B O   1 
ATOM   3914 C  CB  . PRO A 1 583 ? 121.470 103.805 100.014 1.00 77.38  ? 583 PRO B CB  1 
ATOM   3915 C  CG  . PRO A 1 583 ? 122.869 103.488 100.492 1.00 77.38  ? 583 PRO B CG  1 
ATOM   3916 C  CD  . PRO A 1 583 ? 123.537 102.574 99.498  1.00 77.38  ? 583 PRO B CD  1 
ATOM   3917 N  N   . SER A 1 584 ? 120.530 105.099 97.308  1.00 82.30  ? 584 SER B N   1 
ATOM   3918 C  CA  . SER A 1 584 ? 120.599 106.240 96.404  1.00 82.30  ? 584 SER B CA  1 
ATOM   3919 C  C   . SER A 1 584 ? 121.245 107.453 97.060  1.00 82.30  ? 584 SER B C   1 
ATOM   3920 O  O   . SER A 1 584 ? 121.886 108.254 96.371  1.00 82.30  ? 584 SER B O   1 
ATOM   3921 C  CB  . SER A 1 584 ? 119.199 106.597 95.903  1.00 82.30  ? 584 SER B CB  1 
ATOM   3922 O  OG  . SER A 1 584 ? 118.376 107.044 96.966  1.00 82.30  ? 584 SER B OG  1 
ATOM   3923 N  N   . TRP A 1 585 ? 121.086 107.612 98.377  1.00 78.08  ? 585 TRP B N   1 
ATOM   3924 C  CA  . TRP A 1 585 ? 121.666 108.769 99.051  1.00 78.08  ? 585 TRP B CA  1 
ATOM   3925 C  C   . TRP A 1 585 ? 123.186 108.689 99.105  1.00 78.08  ? 585 TRP B C   1 
ATOM   3926 O  O   . TRP A 1 585 ? 123.857 109.726 99.164  1.00 78.08  ? 585 TRP B O   1 
ATOM   3927 C  CB  . TRP A 1 585 ? 121.081 108.908 100.459 1.00 78.08  ? 585 TRP B CB  1 
ATOM   3928 C  CG  . TRP A 1 585 ? 121.446 107.805 101.410 1.00 78.08  ? 585 TRP B CG  1 
ATOM   3929 C  CD1 . TRP A 1 585 ? 122.634 107.641 102.062 1.00 78.08  ? 585 TRP B CD1 1 
ATOM   3930 C  CD2 . TRP A 1 585 ? 120.606 106.724 101.833 1.00 78.08  ? 585 TRP B CD2 1 
ATOM   3931 N  NE1 . TRP A 1 585 ? 122.589 106.521 102.855 1.00 78.08  ? 585 TRP B NE1 1 
ATOM   3932 C  CE2 . TRP A 1 585 ? 121.355 105.941 102.733 1.00 78.08  ? 585 TRP B CE2 1 
ATOM   3933 C  CE3 . TRP A 1 585 ? 119.295 106.342 101.535 1.00 78.08  ? 585 TRP B CE3 1 
ATOM   3934 C  CZ2 . TRP A 1 585 ? 120.837 104.798 103.336 1.00 78.08  ? 585 TRP B CZ2 1 
ATOM   3935 C  CZ3 . TRP A 1 585 ? 118.784 105.206 102.134 1.00 78.08  ? 585 TRP B CZ3 1 
ATOM   3936 C  CH2 . TRP A 1 585 ? 119.553 104.448 103.024 1.00 78.08  ? 585 TRP B CH2 1 
ATOM   3937 N  N   . ALA A 1 586 ? 123.743 107.482 99.091  1.00 79.81  ? 586 ALA B N   1 
ATOM   3938 C  CA  . ALA A 1 586 ? 125.186 107.327 99.072  1.00 79.81  ? 586 ALA B CA  1 
ATOM   3939 C  C   . ALA A 1 586 ? 125.750 107.791 97.729  1.00 79.81  ? 586 ALA B C   1 
ATOM   3940 O  O   . ALA A 1 586 ? 125.113 107.619 96.687  1.00 79.81  ? 586 ALA B O   1 
ATOM   3941 C  CB  . ALA A 1 586 ? 125.569 105.872 99.324  1.00 79.81  ? 586 ALA B CB  1 
ATOM   3942 N  N   . PRO A 1 587 ? 126.941 108.382 97.725  1.00 78.66  ? 587 PRO B N   1 
ATOM   3943 C  CA  . PRO A 1 587 ? 127.523 108.857 96.467  1.00 78.66  ? 587 PRO B CA  1 
ATOM   3944 C  C   . PRO A 1 587 ? 128.000 107.705 95.596  1.00 78.66  ? 587 PRO B C   1 
ATOM   3945 O  O   . PRO A 1 587 ? 128.280 106.601 96.066  1.00 78.66  ? 587 PRO B O   1 
ATOM   3946 C  CB  . PRO A 1 587 ? 128.699 109.733 96.916  1.00 78.66  ? 587 PRO B CB  1 
ATOM   3947 C  CG  . PRO A 1 587 ? 128.993 109.338 98.323  1.00 78.66  ? 587 PRO B CG  1 
ATOM   3948 C  CD  . PRO A 1 587 ? 127.878 108.485 98.855  1.00 78.66  ? 587 PRO B CD  1 
ATOM   3949 N  N   . ALA A 1 588 ? 128.083 107.986 94.301  1.00 84.82  ? 588 ALA B N   1 
ATOM   3950 C  CA  . ALA A 1 588 ? 128.510 106.991 93.325  1.00 84.82  ? 588 ALA B CA  1 
ATOM   3951 C  C   . ALA A 1 588 ? 129.995 106.680 93.471  1.00 84.82  ? 588 ALA B C   1 
ATOM   3952 O  O   . ALA A 1 588 ? 130.458 105.613 93.068  1.00 84.82  ? 588 ALA B O   1 
ATOM   3953 C  CB  . ALA A 1 588 ? 128.205 107.469 91.914  1.00 84.82  ? 588 ALA B CB  1 
ATOM   3954 N  N   . LYS B 1 2   ? 88.637  135.482 145.481 1.00 107.79 ? 2   LYS A N   1 
ATOM   3955 C  CA  . LYS B 1 2   ? 90.045  135.110 145.414 1.00 107.79 ? 2   LYS A CA  1 
ATOM   3956 C  C   . LYS B 1 2   ? 90.498  134.990 143.962 1.00 107.79 ? 2   LYS A C   1 
ATOM   3957 O  O   . LYS B 1 2   ? 91.666  134.717 143.684 1.00 107.79 ? 2   LYS A O   1 
ATOM   3958 C  CB  . LYS B 1 2   ? 90.288  133.796 146.161 1.00 107.79 ? 2   LYS A CB  1 
ATOM   3959 C  CG  . LYS B 1 2   ? 91.721  133.601 146.631 1.00 107.79 ? 2   LYS A CG  1 
ATOM   3960 C  CD  . LYS B 1 2   ? 92.110  134.654 147.656 1.00 107.79 ? 2   LYS A CD  1 
ATOM   3961 C  CE  . LYS B 1 2   ? 93.510  134.410 148.195 1.00 107.79 ? 2   LYS A CE  1 
ATOM   3962 N  NZ  . LYS B 1 2   ? 93.920  135.459 149.168 1.00 107.79 ? 2   LYS A NZ  1 
ATOM   3963 N  N   . PHE B 1 3   ? 89.559  135.200 143.037 1.00 109.56 ? 3   PHE A N   1 
ATOM   3964 C  CA  . PHE B 1 3   ? 89.888  135.123 141.617 1.00 109.56 ? 3   PHE A CA  1 
ATOM   3965 C  C   . PHE B 1 3   ? 90.861  136.219 141.206 1.00 109.56 ? 3   PHE A C   1 
ATOM   3966 O  O   . PHE B 1 3   ? 91.723  135.993 140.348 1.00 109.56 ? 3   PHE A O   1 
ATOM   3967 C  CB  . PHE B 1 3   ? 88.613  135.207 140.779 1.00 109.56 ? 3   PHE A CB  1 
ATOM   3968 C  CG  . PHE B 1 3   ? 87.703  134.025 140.942 1.00 109.56 ? 3   PHE A CG  1 
ATOM   3969 C  CD1 . PHE B 1 3   ? 87.947  132.846 140.258 1.00 109.56 ? 3   PHE A CD1 1 
ATOM   3970 C  CD2 . PHE B 1 3   ? 86.604  134.092 141.782 1.00 109.56 ? 3   PHE A CD2 1 
ATOM   3971 C  CE1 . PHE B 1 3   ? 87.110  131.756 140.406 1.00 109.56 ? 3   PHE A CE1 1 
ATOM   3972 C  CE2 . PHE B 1 3   ? 85.763  133.005 141.935 1.00 109.56 ? 3   PHE A CE2 1 
ATOM   3973 C  CZ  . PHE B 1 3   ? 86.017  131.836 141.246 1.00 109.56 ? 3   PHE A CZ  1 
ATOM   3974 N  N   . PHE B 1 4   ? 90.736  137.409 141.798 1.00 108.86 ? 4   PHE A N   1 
ATOM   3975 C  CA  . PHE B 1 4   ? 91.594  138.526 141.416 1.00 108.86 ? 4   PHE A CA  1 
ATOM   3976 C  C   . PHE B 1 4   ? 93.058  138.225 141.712 1.00 108.86 ? 4   PHE A C   1 
ATOM   3977 O  O   . PHE B 1 4   ? 93.930  138.441 140.861 1.00 108.86 ? 4   PHE A O   1 
ATOM   3978 C  CB  . PHE B 1 4   ? 91.152  139.794 142.146 1.00 108.86 ? 4   PHE A CB  1 
ATOM   3979 C  CG  . PHE B 1 4   ? 89.810  140.313 141.707 1.00 108.86 ? 4   PHE A CG  1 
ATOM   3980 C  CD1 . PHE B 1 4   ? 89.221  139.858 140.538 1.00 108.86 ? 4   PHE A CD1 1 
ATOM   3981 C  CD2 . PHE B 1 4   ? 89.133  141.249 142.471 1.00 108.86 ? 4   PHE A CD2 1 
ATOM   3982 C  CE1 . PHE B 1 4   ? 87.986  140.332 140.137 1.00 108.86 ? 4   PHE A CE1 1 
ATOM   3983 C  CE2 . PHE B 1 4   ? 87.898  141.726 142.076 1.00 108.86 ? 4   PHE A CE2 1 
ATOM   3984 C  CZ  . PHE B 1 4   ? 87.324  141.267 140.907 1.00 108.86 ? 4   PHE A CZ  1 
ATOM   3985 N  N   . SER B 1 5   ? 93.345  137.717 142.912 1.00 104.90 ? 5   SER A N   1 
ATOM   3986 C  CA  . SER B 1 5   ? 94.721  137.378 143.264 1.00 104.90 ? 5   SER A CA  1 
ATOM   3987 C  C   . SER B 1 5   ? 95.256  136.255 142.385 1.00 104.90 ? 5   SER A C   1 
ATOM   3988 O  O   . SER B 1 5   ? 96.416  136.292 141.958 1.00 104.90 ? 5   SER A O   1 
ATOM   3989 C  CB  . SER B 1 5   ? 94.804  136.992 144.740 1.00 104.90 ? 5   SER A CB  1 
ATOM   3990 O  OG  . SER B 1 5   ? 96.132  136.657 145.105 1.00 104.90 ? 5   SER A OG  1 
ATOM   3991 N  N   . TYR B 1 6   ? 94.426  135.248 142.106 1.00 101.58 ? 6   TYR A N   1 
ATOM   3992 C  CA  . TYR B 1 6   ? 94.868  134.138 141.269 1.00 101.58 ? 6   TYR A CA  1 
ATOM   3993 C  C   . TYR B 1 6   ? 95.209  134.613 139.862 1.00 101.58 ? 6   TYR A C   1 
ATOM   3994 O  O   . TYR B 1 6   ? 96.205  134.175 139.275 1.00 101.58 ? 6   TYR A O   1 
ATOM   3995 C  CB  . TYR B 1 6   ? 93.791  133.054 141.227 1.00 101.58 ? 6   TYR A CB  1 
ATOM   3996 C  CG  . TYR B 1 6   ? 93.790  132.146 142.437 1.00 101.58 ? 6   TYR A CG  1 
ATOM   3997 C  CD1 . TYR B 1 6   ? 94.625  132.396 143.519 1.00 101.58 ? 6   TYR A CD1 1 
ATOM   3998 C  CD2 . TYR B 1 6   ? 92.951  131.041 142.499 1.00 101.58 ? 6   TYR A CD2 1 
ATOM   3999 C  CE1 . TYR B 1 6   ? 94.625  131.570 144.627 1.00 101.58 ? 6   TYR A CE1 1 
ATOM   4000 C  CE2 . TYR B 1 6   ? 92.945  130.209 143.603 1.00 101.58 ? 6   TYR A CE2 1 
ATOM   4001 C  CZ  . TYR B 1 6   ? 93.784  130.479 144.664 1.00 101.58 ? 6   TYR A CZ  1 
ATOM   4002 O  OH  . TYR B 1 6   ? 93.781  129.654 145.765 1.00 101.58 ? 6   TYR A OH  1 
ATOM   4003 N  N   . ILE B 1 7   ? 94.393  135.510 139.305 1.00 96.79  ? 7   ILE A N   1 
ATOM   4004 C  CA  . ILE B 1 7   ? 94.694  136.071 137.992 1.00 96.79  ? 7   ILE A CA  1 
ATOM   4005 C  C   . ILE B 1 7   ? 95.973  136.896 138.046 1.00 96.79  ? 7   ILE A C   1 
ATOM   4006 O  O   . ILE B 1 7   ? 96.826  136.806 137.155 1.00 96.79  ? 7   ILE A O   1 
ATOM   4007 C  CB  . ILE B 1 7   ? 93.504  136.902 137.478 1.00 96.79  ? 7   ILE A CB  1 
ATOM   4008 C  CG1 . ILE B 1 7   ? 92.325  135.990 137.130 1.00 96.79  ? 7   ILE A CG1 1 
ATOM   4009 C  CG2 . ILE B 1 7   ? 93.910  137.732 136.271 1.00 96.79  ? 7   ILE A CG2 1 
ATOM   4010 C  CD1 . ILE B 1 7   ? 92.694  134.825 136.240 1.00 96.79  ? 7   ILE A CD1 1 
ATOM   4011 N  N   . LEU B 1 8   ? 96.133  137.706 139.095 1.00 94.01  ? 8   LEU A N   1 
ATOM   4012 C  CA  . LEU B 1 8   ? 97.314  138.553 139.211 1.00 94.01  ? 8   LEU A CA  1 
ATOM   4013 C  C   . LEU B 1 8   ? 98.585  137.747 139.456 1.00 94.01  ? 8   LEU A C   1 
ATOM   4014 O  O   . LEU B 1 8   ? 99.684  138.260 139.225 1.00 94.01  ? 8   LEU A O   1 
ATOM   4015 C  CB  . LEU B 1 8   ? 97.098  139.586 140.323 1.00 94.01  ? 8   LEU A CB  1 
ATOM   4016 C  CG  . LEU B 1 8   ? 98.082  140.743 140.534 1.00 94.01  ? 8   LEU A CG  1 
ATOM   4017 C  CD1 . LEU B 1 8   ? 97.342  141.946 141.089 1.00 94.01  ? 8   LEU A CD1 1 
ATOM   4018 C  CD2 . LEU B 1 8   ? 99.209  140.359 141.482 1.00 94.01  ? 8   LEU A CD2 1 
ATOM   4019 N  N   . VAL B 1 9   ? 98.466  136.500 139.911 1.00 89.62  ? 9   VAL A N   1 
ATOM   4020 C  CA  . VAL B 1 9   ? 99.654  135.680 140.126 1.00 89.62  ? 9   VAL A CA  1 
ATOM   4021 C  C   . VAL B 1 9   ? 100.083 134.999 138.833 1.00 89.62  ? 9   VAL A C   1 
ATOM   4022 O  O   . VAL B 1 9   ? 101.251 135.070 138.434 1.00 89.62  ? 9   VAL A O   1 
ATOM   4023 C  CB  . VAL B 1 9   ? 99.404  134.655 141.248 1.00 89.62  ? 9   VAL A CB  1 
ATOM   4024 C  CG1 . VAL B 1 9   ? 100.464 133.568 141.213 1.00 89.62  ? 9   VAL A CG1 1 
ATOM   4025 C  CG2 . VAL B 1 9   ? 99.399  135.344 142.601 1.00 89.62  ? 9   VAL A CG2 1 
ATOM   4026 N  N   . TYR B 1 10  ? 99.153  134.328 138.161 1.00 82.24  ? 10  TYR A N   1 
ATOM   4027 C  CA  . TYR B 1 10  ? 99.458  133.592 136.934 1.00 82.24  ? 10  TYR A CA  1 
ATOM   4028 C  C   . TYR B 1 10  ? 99.150  134.440 135.700 1.00 82.24  ? 10  TYR A C   1 
ATOM   4029 O  O   . TYR B 1 10  ? 98.366  134.061 134.831 1.00 82.24  ? 10  TYR A O   1 
ATOM   4030 C  CB  . TYR B 1 10  ? 98.686  132.276 136.901 1.00 82.24  ? 10  TYR A CB  1 
ATOM   4031 C  CG  . TYR B 1 10  ? 98.918  131.391 138.104 1.00 82.24  ? 10  TYR A CG  1 
ATOM   4032 C  CD1 . TYR B 1 10  ? 98.173  131.553 139.264 1.00 82.24  ? 10  TYR A CD1 1 
ATOM   4033 C  CD2 . TYR B 1 10  ? 99.881  130.394 138.079 1.00 82.24  ? 10  TYR A CD2 1 
ATOM   4034 C  CE1 . TYR B 1 10  ? 98.382  130.748 140.364 1.00 82.24  ? 10  TYR A CE1 1 
ATOM   4035 C  CE2 . TYR B 1 10  ? 100.097 129.583 139.176 1.00 82.24  ? 10  TYR A CE2 1 
ATOM   4036 C  CZ  . TYR B 1 10  ? 99.345  129.765 140.315 1.00 82.24  ? 10  TYR A CZ  1 
ATOM   4037 O  OH  . TYR B 1 10  ? 99.556  128.959 141.410 1.00 82.24  ? 10  TYR A OH  1 
ATOM   4038 N  N   . ARG B 1 11  ? 99.783  135.613 135.628 1.00 75.91  ? 11  ARG A N   1 
ATOM   4039 C  CA  . ARG B 1 11  ? 99.619  136.447 134.443 1.00 75.91  ? 11  ARG A CA  1 
ATOM   4040 C  C   . ARG B 1 11  ? 100.371 135.877 133.251 1.00 75.91  ? 11  ARG A C   1 
ATOM   4041 O  O   . ARG B 1 11  ? 99.925  136.028 132.110 1.00 75.91  ? 11  ARG A O   1 
ATOM   4042 C  CB  . ARG B 1 11  ? 100.092 137.874 134.715 1.00 75.91  ? 11  ARG A CB  1 
ATOM   4043 C  CG  . ARG B 1 11  ? 99.804  138.382 136.109 1.00 75.91  ? 11  ARG A CG  1 
ATOM   4044 C  CD  . ARG B 1 11  ? 100.796 139.462 136.500 1.00 75.91  ? 11  ARG A CD  1 
ATOM   4045 N  NE  . ARG B 1 11  ? 102.169 138.976 136.458 1.00 75.91  ? 11  ARG A NE  1 
ATOM   4046 C  CZ  . ARG B 1 11  ? 103.222 139.731 136.180 1.00 75.91  ? 11  ARG A CZ  1 
ATOM   4047 N  NH1 . ARG B 1 11  ? 103.096 141.020 135.911 1.00 75.91  ? 11  ARG A NH1 1 
ATOM   4048 N  NH2 . ARG B 1 11  ? 104.432 139.180 136.171 1.00 75.91  ? 11  ARG A NH2 1 
ATOM   4049 N  N   . ARG B 1 12  ? 101.508 135.226 133.493 1.00 70.91  ? 12  ARG A N   1 
ATOM   4050 C  CA  . ARG B 1 12  ? 102.345 134.740 132.402 1.00 70.91  ? 12  ARG A CA  1 
ATOM   4051 C  C   . ARG B 1 12  ? 101.649 133.634 131.616 1.00 70.91  ? 12  ARG A C   1 
ATOM   4052 O  O   . ARG B 1 12  ? 101.555 133.696 130.384 1.00 70.91  ? 12  ARG A O   1 
ATOM   4053 C  CB  . ARG B 1 12  ? 103.674 134.252 132.974 1.00 70.91  ? 12  ARG A CB  1 
ATOM   4054 C  CG  . ARG B 1 12  ? 104.739 133.922 131.958 1.00 70.91  ? 12  ARG A CG  1 
ATOM   4055 C  CD  . ARG B 1 12  ? 106.032 133.542 132.664 1.00 70.91  ? 12  ARG A CD  1 
ATOM   4056 N  NE  . ARG B 1 12  ? 106.559 134.649 133.453 1.00 70.91  ? 12  ARG A NE  1 
ATOM   4057 C  CZ  . ARG B 1 12  ? 106.626 134.659 134.778 1.00 70.91  ? 12  ARG A CZ  1 
ATOM   4058 N  NH1 . ARG B 1 12  ? 106.212 133.630 135.498 1.00 70.91  ? 12  ARG A NH1 1 
ATOM   4059 N  NH2 . ARG B 1 12  ? 107.118 135.730 135.394 1.00 70.91  ? 12  ARG A NH2 1 
ATOM   4060 N  N   . PHE B 1 13  ? 101.146 132.616 132.317 1.00 65.41  ? 13  PHE A N   1 
ATOM   4061 C  CA  . PHE B 1 13  ? 100.469 131.504 131.656 1.00 65.41  ? 13  PHE A CA  1 
ATOM   4062 C  C   . PHE B 1 13  ? 99.212  131.978 130.935 1.00 65.41  ? 13  PHE A C   1 
ATOM   4063 O  O   . PHE B 1 13  ? 98.960  131.605 129.779 1.00 65.41  ? 13  PHE A O   1 
ATOM   4064 C  CB  . PHE B 1 13  ? 100.132 130.433 132.695 1.00 65.41  ? 13  PHE A CB  1 
ATOM   4065 C  CG  . PHE B 1 13  ? 99.525  129.186 132.121 1.00 65.41  ? 13  PHE A CG  1 
ATOM   4066 C  CD1 . PHE B 1 13  ? 98.153  129.067 131.987 1.00 65.41  ? 13  PHE A CD1 1 
ATOM   4067 C  CD2 . PHE B 1 13  ? 100.323 128.124 131.741 1.00 65.41  ? 13  PHE A CD2 1 
ATOM   4068 C  CE1 . PHE B 1 13  ? 97.593  127.920 131.470 1.00 65.41  ? 13  PHE A CE1 1 
ATOM   4069 C  CE2 . PHE B 1 13  ? 99.766  126.974 131.225 1.00 65.41  ? 13  PHE A CE2 1 
ATOM   4070 C  CZ  . PHE B 1 13  ? 98.401  126.872 131.089 1.00 65.41  ? 13  PHE A CZ  1 
ATOM   4071 N  N   . LEU B 1 14  ? 98.412  132.807 131.608 1.00 66.59  ? 14  LEU A N   1 
ATOM   4072 C  CA  . LEU B 1 14  ? 97.184  133.305 131.003 1.00 66.59  ? 14  LEU A CA  1 
ATOM   4073 C  C   . LEU B 1 14  ? 97.481  134.143 129.769 1.00 66.59  ? 14  LEU A C   1 
ATOM   4074 O  O   . LEU B 1 14  ? 96.791  134.024 128.751 1.00 66.59  ? 14  LEU A O   1 
ATOM   4075 C  CB  . LEU B 1 14  ? 96.385  134.117 132.022 1.00 66.59  ? 14  LEU A CB  1 
ATOM   4076 C  CG  . LEU B 1 14  ? 95.316  133.366 132.818 1.00 66.59  ? 14  LEU A CG  1 
ATOM   4077 C  CD1 . LEU B 1 14  ? 94.229  132.858 131.885 1.00 66.59  ? 14  LEU A CD1 1 
ATOM   4078 C  CD2 . LEU B 1 14  ? 95.916  132.223 133.621 1.00 66.59  ? 14  LEU A CD2 1 
ATOM   4079 N  N   . PHE B 1 15  ? 98.506  134.994 129.838 1.00 63.37  ? 15  PHE A N   1 
ATOM   4080 C  CA  . PHE B 1 15  ? 98.845  135.824 128.689 1.00 63.37  ? 15  PHE A CA  1 
ATOM   4081 C  C   . PHE B 1 15  ? 99.358  134.985 127.530 1.00 63.37  ? 15  PHE A C   1 
ATOM   4082 O  O   . PHE B 1 15  ? 99.031  135.263 126.373 1.00 63.37  ? 15  PHE A O   1 
ATOM   4083 C  CB  . PHE B 1 15  ? 99.877  136.879 129.070 1.00 63.37  ? 15  PHE A CB  1 
ATOM   4084 C  CG  . PHE B 1 15  ? 100.168 137.847 127.966 1.00 63.37  ? 15  PHE A CG  1 
ATOM   4085 C  CD1 . PHE B 1 15  ? 99.135  138.494 127.311 1.00 63.37  ? 15  PHE A CD1 1 
ATOM   4086 C  CD2 . PHE B 1 15  ? 101.467 138.093 127.563 1.00 63.37  ? 15  PHE A CD2 1 
ATOM   4087 C  CE1 . PHE B 1 15  ? 99.392  139.382 126.288 1.00 63.37  ? 15  PHE A CE1 1 
ATOM   4088 C  CE2 . PHE B 1 15  ? 101.730 138.978 126.537 1.00 63.37  ? 15  PHE A CE2 1 
ATOM   4089 C  CZ  . PHE B 1 15  ? 100.691 139.624 125.900 1.00 63.37  ? 15  PHE A CZ  1 
ATOM   4090 N  N   . VAL B 1 16  ? 100.171 133.964 127.812 1.00 62.45  ? 16  VAL A N   1 
ATOM   4091 C  CA  . VAL B 1 16  ? 100.652 133.094 126.740 1.00 62.45  ? 16  VAL A CA  1 
ATOM   4092 C  C   . VAL B 1 16  ? 99.478  132.414 126.051 1.00 62.45  ? 16  VAL A C   1 
ATOM   4093 O  O   . VAL B 1 16  ? 99.378  132.400 124.816 1.00 62.45  ? 16  VAL A O   1 
ATOM   4094 C  CB  . VAL B 1 16  ? 101.652 132.062 127.291 1.00 62.45  ? 16  VAL A CB  1 
ATOM   4095 C  CG1 . VAL B 1 16  ? 101.861 130.943 126.287 1.00 62.45  ? 16  VAL A CG1 1 
ATOM   4096 C  CG2 . VAL B 1 16  ? 102.967 132.725 127.626 1.00 62.45  ? 16  VAL A CG2 1 
ATOM   4097 N  N   . VAL B 1 17  ? 98.557  131.858 126.844 1.00 66.83  ? 17  VAL A N   1 
ATOM   4098 C  CA  . VAL B 1 17  ? 97.410  131.163 126.268 1.00 66.83  ? 17  VAL A CA  1 
ATOM   4099 C  C   . VAL B 1 17  ? 96.551  132.127 125.458 1.00 66.83  ? 17  VAL A C   1 
ATOM   4100 O  O   . VAL B 1 17  ? 96.125  131.813 124.339 1.00 66.83  ? 17  VAL A O   1 
ATOM   4101 C  CB  . VAL B 1 17  ? 96.598  130.470 127.376 1.00 66.83  ? 17  VAL A CB  1 
ATOM   4102 C  CG1 . VAL B 1 17  ? 95.232  130.053 126.857 1.00 66.83  ? 17  VAL A CG1 1 
ATOM   4103 C  CG2 . VAL B 1 17  ? 97.359  129.270 127.911 1.00 66.83  ? 17  VAL A CG2 1 
ATOM   4104 N  N   . PHE B 1 18  ? 96.288  133.317 126.005 1.00 67.12  ? 18  PHE A N   1 
ATOM   4105 C  CA  . PHE B 1 18  ? 95.451  134.287 125.310 1.00 67.12  ? 18  PHE A CA  1 
ATOM   4106 C  C   . PHE B 1 18  ? 96.093  134.747 124.009 1.00 67.12  ? 18  PHE A C   1 
ATOM   4107 O  O   . PHE B 1 18  ? 95.417  134.855 122.981 1.00 67.12  ? 18  PHE A O   1 
ATOM   4108 C  CB  . PHE B 1 18  ? 95.173  135.481 126.221 1.00 67.12  ? 18  PHE A CB  1 
ATOM   4109 C  CG  . PHE B 1 18  ? 94.282  136.517 125.606 1.00 67.12  ? 18  PHE A CG  1 
ATOM   4110 C  CD1 . PHE B 1 18  ? 93.089  136.154 125.004 1.00 67.12  ? 18  PHE A CD1 1 
ATOM   4111 C  CD2 . PHE B 1 18  ? 94.636  137.855 125.629 1.00 67.12  ? 18  PHE A CD2 1 
ATOM   4112 C  CE1 . PHE B 1 18  ? 92.265  137.106 124.436 1.00 67.12  ? 18  PHE A CE1 1 
ATOM   4113 C  CE2 . PHE B 1 18  ? 93.817  138.812 125.062 1.00 67.12  ? 18  PHE A CE2 1 
ATOM   4114 C  CZ  . PHE B 1 18  ? 92.630  138.436 124.465 1.00 67.12  ? 18  PHE A CZ  1 
ATOM   4115 N  N   . THR B 1 19  ? 97.398  135.030 124.033 1.00 65.70  ? 19  THR A N   1 
ATOM   4116 C  CA  . THR B 1 19  ? 98.084  135.466 122.822 1.00 65.70  ? 19  THR A CA  1 
ATOM   4117 C  C   . THR B 1 19  ? 98.064  134.377 121.762 1.00 65.70  ? 19  THR A C   1 
ATOM   4118 O  O   . THR B 1 19  ? 97.860  134.660 120.576 1.00 65.70  ? 19  THR A O   1 
ATOM   4119 C  CB  . THR B 1 19  ? 99.523  135.868 123.146 1.00 65.70  ? 19  THR A CB  1 
ATOM   4120 O  OG1 . THR B 1 19  ? 99.518  136.945 124.091 1.00 65.70  ? 19  THR A OG1 1 
ATOM   4121 C  CG2 . THR B 1 19  ? 100.247 136.314 121.889 1.00 65.70  ? 19  THR A CG2 1 
ATOM   4122 N  N   . VAL B 1 20  ? 98.272  133.123 122.168 1.00 65.92  ? 20  VAL A N   1 
ATOM   4123 C  CA  . VAL B 1 20  ? 98.233  132.026 121.205 1.00 65.92  ? 20  VAL A CA  1 
ATOM   4124 C  C   . VAL B 1 20  ? 96.841  131.904 120.597 1.00 65.92  ? 20  VAL A C   1 
ATOM   4125 O  O   . VAL B 1 20  ? 96.688  131.774 119.378 1.00 65.92  ? 20  VAL A O   1 
ATOM   4126 C  CB  . VAL B 1 20  ? 98.679  130.711 121.869 1.00 65.92  ? 20  VAL A CB  1 
ATOM   4127 C  CG1 . VAL B 1 20  ? 98.324  129.528 120.990 1.00 65.92  ? 20  VAL A CG1 1 
ATOM   4128 C  CG2 . VAL B 1 20  ? 100.173 130.740 122.136 1.00 65.92  ? 20  VAL A CG2 1 
ATOM   4129 N  N   . LEU B 1 21  ? 95.804  131.965 121.435 1.00 70.48  ? 21  LEU A N   1 
ATOM   4130 C  CA  . LEU B 1 21  ? 94.457  131.652 120.965 1.00 70.48  ? 21  LEU A CA  1 
ATOM   4131 C  C   . LEU B 1 21  ? 93.825  132.788 120.164 1.00 70.48  ? 21  LEU A C   1 
ATOM   4132 O  O   . LEU B 1 21  ? 93.171  132.532 119.148 1.00 70.48  ? 21  LEU A O   1 
ATOM   4133 C  CB  . LEU B 1 21  ? 93.560  131.283 122.148 1.00 70.48  ? 21  LEU A CB  1 
ATOM   4134 C  CG  . LEU B 1 21  ? 93.477  129.800 122.521 1.00 70.48  ? 21  LEU A CG  1 
ATOM   4135 C  CD1 . LEU B 1 21  ? 92.856  129.009 121.382 1.00 70.48  ? 21  LEU A CD1 1 
ATOM   4136 C  CD2 . LEU B 1 21  ? 94.836  129.228 122.889 1.00 70.48  ? 21  LEU A CD2 1 
ATOM   4137 N  N   . VAL B 1 22  ? 93.999  134.041 120.594 1.00 69.92  ? 22  VAL A N   1 
ATOM   4138 C  CA  . VAL B 1 22  ? 93.178  135.122 120.055 1.00 69.92  ? 22  VAL A CA  1 
ATOM   4139 C  C   . VAL B 1 22  ? 93.506  135.442 118.599 1.00 69.92  ? 22  VAL A C   1 
ATOM   4140 O  O   . VAL B 1 22  ? 92.676  136.036 117.901 1.00 69.92  ? 22  VAL A O   1 
ATOM   4141 C  CB  . VAL B 1 22  ? 93.309  136.378 120.942 1.00 69.92  ? 22  VAL A CB  1 
ATOM   4142 C  CG1 . VAL B 1 22  ? 94.677  137.011 120.789 1.00 69.92  ? 22  VAL A CG1 1 
ATOM   4143 C  CG2 . VAL B 1 22  ? 92.201  137.380 120.640 1.00 69.92  ? 22  VAL A CG2 1 
ATOM   4144 N  N   . LEU B 1 23  ? 94.680  135.058 118.108 1.00 70.82  ? 23  LEU A N   1 
ATOM   4145 C  CA  . LEU B 1 23  ? 95.048  135.339 116.726 1.00 70.82  ? 23  LEU A CA  1 
ATOM   4146 C  C   . LEU B 1 23  ? 94.616  134.252 115.751 1.00 70.82  ? 23  LEU A C   1 
ATOM   4147 O  O   . LEU B 1 23  ? 94.890  134.380 114.554 1.00 70.82  ? 23  LEU A O   1 
ATOM   4148 C  CB  . LEU B 1 23  ? 96.559  135.554 116.599 1.00 70.82  ? 23  LEU A CB  1 
ATOM   4149 C  CG  . LEU B 1 23  ? 97.155  136.933 116.887 1.00 70.82  ? 23  LEU A CG  1 
ATOM   4150 C  CD1 . LEU B 1 23  ? 97.218  137.228 118.371 1.00 70.82  ? 23  LEU A CD1 1 
ATOM   4151 C  CD2 . LEU B 1 23  ? 98.532  137.030 116.270 1.00 70.82  ? 23  LEU A CD2 1 
ATOM   4152 N  N   . LEU B 1 24  ? 93.959  133.193 116.224 1.00 76.49  ? 24  LEU A N   1 
ATOM   4153 C  CA  . LEU B 1 24  ? 93.481  132.154 115.316 1.00 76.49  ? 24  LEU A CA  1 
ATOM   4154 C  C   . LEU B 1 24  ? 92.541  132.651 114.217 1.00 76.49  ? 24  LEU A C   1 
ATOM   4155 O  O   . LEU B 1 24  ? 92.512  132.009 113.151 1.00 76.49  ? 24  LEU A O   1 
ATOM   4156 C  CB  . LEU B 1 24  ? 92.801  131.032 116.116 1.00 76.49  ? 24  LEU A CB  1 
ATOM   4157 C  CG  . LEU B 1 24  ? 93.674  129.840 116.511 1.00 76.49  ? 24  LEU A CG  1 
ATOM   4158 C  CD1 . LEU B 1 24  ? 94.137  129.096 115.270 1.00 76.49  ? 24  LEU A CD1 1 
ATOM   4159 C  CD2 . LEU B 1 24  ? 94.862  130.273 117.340 1.00 76.49  ? 24  LEU A CD2 1 
ATOM   4160 N  N   . PRO B 1 25  ? 91.749  133.718 114.398 1.00 78.16  ? 25  PRO A N   1 
ATOM   4161 C  CA  . PRO B 1 25  ? 90.974  134.237 113.260 1.00 78.16  ? 25  PRO A CA  1 
ATOM   4162 C  C   . PRO B 1 25  ? 91.806  134.520 112.022 1.00 78.16  ? 25  PRO A C   1 
ATOM   4163 O  O   . PRO B 1 25  ? 91.339  134.259 110.908 1.00 78.16  ? 25  PRO A O   1 
ATOM   4164 C  CB  . PRO B 1 25  ? 90.354  135.520 113.826 1.00 78.16  ? 25  PRO A CB  1 
ATOM   4165 C  CG  . PRO B 1 25  ? 90.204  135.258 115.277 1.00 78.16  ? 25  PRO A CG  1 
ATOM   4166 C  CD  . PRO B 1 25  ? 91.196  134.197 115.680 1.00 78.16  ? 25  PRO A CD  1 
ATOM   4167 N  N   . LEU B 1 26  ? 93.024  135.038 112.177 1.00 78.80  ? 26  LEU A N   1 
ATOM   4168 C  CA  . LEU B 1 26  ? 93.837  135.351 111.003 1.00 78.80  ? 26  LEU A CA  1 
ATOM   4169 C  C   . LEU B 1 26  ? 94.107  134.127 110.136 1.00 78.80  ? 26  LEU A C   1 
ATOM   4170 O  O   . LEU B 1 26  ? 93.942  134.224 108.908 1.00 78.80  ? 26  LEU A O   1 
ATOM   4171 C  CB  . LEU B 1 26  ? 95.134  136.045 111.436 1.00 78.80  ? 26  LEU A CB  1 
ATOM   4172 C  CG  . LEU B 1 26  ? 95.170  137.572 111.351 1.00 78.80  ? 26  LEU A CG  1 
ATOM   4173 C  CD1 . LEU B 1 26  ? 94.004  138.193 112.106 1.00 78.80  ? 26  LEU A CD1 1 
ATOM   4174 C  CD2 . LEU B 1 26  ? 96.494  138.105 111.874 1.00 78.80  ? 26  LEU A CD2 1 
ATOM   4175 N  N   . PRO B 1 27  ? 94.515  132.970 110.671 1.00 78.65  ? 27  PRO A N   1 
ATOM   4176 C  CA  . PRO B 1 27  ? 94.617  131.793 109.795 1.00 78.65  ? 27  PRO A CA  1 
ATOM   4177 C  C   . PRO B 1 27  ? 93.279  131.183 109.411 1.00 78.65  ? 27  PRO A C   1 
ATOM   4178 O  O   . PRO B 1 27  ? 93.105  130.806 108.245 1.00 78.65  ? 27  PRO A O   1 
ATOM   4179 C  CB  . PRO B 1 27  ? 95.470  130.816 110.618 1.00 78.65  ? 27  PRO A CB  1 
ATOM   4180 C  CG  . PRO B 1 27  ? 96.199  131.671 111.581 1.00 78.65  ? 27  PRO A CG  1 
ATOM   4181 C  CD  . PRO B 1 27  ? 95.224  132.740 111.940 1.00 78.65  ? 27  PRO A CD  1 
ATOM   4182 N  N   . ILE B 1 28  ? 92.325  131.062 110.342 1.00 80.92  ? 28  ILE A N   1 
ATOM   4183 C  CA  . ILE B 1 28  ? 91.182  130.187 110.075 1.00 80.92  ? 28  ILE A CA  1 
ATOM   4184 C  C   . ILE B 1 28  ? 90.264  130.777 109.006 1.00 80.92  ? 28  ILE A C   1 
ATOM   4185 O  O   . ILE B 1 28  ? 89.771  130.052 108.134 1.00 80.92  ? 28  ILE A O   1 
ATOM   4186 C  CB  . ILE B 1 28  ? 90.410  129.860 111.370 1.00 80.92  ? 28  ILE A CB  1 
ATOM   4187 C  CG1 . ILE B 1 28  ? 89.823  131.117 112.010 1.00 80.92  ? 28  ILE A CG1 1 
ATOM   4188 C  CG2 . ILE B 1 28  ? 91.305  129.114 112.350 1.00 80.92  ? 28  ILE A CG2 1 
ATOM   4189 C  CD1 . ILE B 1 28  ? 88.867  130.831 113.147 1.00 80.92  ? 28  ILE A CD1 1 
ATOM   4190 N  N   . VAL B 1 29  ? 90.017  132.087 109.044 1.00 83.97  ? 29  VAL A N   1 
ATOM   4191 C  CA  . VAL B 1 29  ? 89.049  132.680 108.124 1.00 83.97  ? 29  VAL A CA  1 
ATOM   4192 C  C   . VAL B 1 29  ? 89.755  133.194 106.876 1.00 83.97  ? 29  VAL A C   1 
ATOM   4193 O  O   . VAL B 1 29  ? 89.144  133.862 106.034 1.00 83.97  ? 29  VAL A O   1 
ATOM   4194 C  CB  . VAL B 1 29  ? 88.231  133.799 108.800 1.00 83.97  ? 29  VAL A CB  1 
ATOM   4195 C  CG1 . VAL B 1 29  ? 87.674  133.324 110.134 1.00 83.97  ? 29  VAL A CG1 1 
ATOM   4196 C  CG2 . VAL B 1 29  ? 89.058  135.059 108.973 1.00 83.97  ? 29  VAL A CG2 1 
ATOM   4197 N  N   . LEU B 1 30  ? 91.039  132.879 106.740 1.00 83.11  ? 30  LEU A N   1 
ATOM   4198 C  CA  . LEU B 1 30  ? 91.792  133.204 105.534 1.00 83.11  ? 30  LEU A CA  1 
ATOM   4199 C  C   . LEU B 1 30  ? 92.295  131.979 104.792 1.00 83.11  ? 30  LEU A C   1 
ATOM   4200 O  O   . LEU B 1 30  ? 92.161  131.914 103.567 1.00 83.11  ? 30  LEU A O   1 
ATOM   4201 C  CB  . LEU B 1 30  ? 92.986  134.111 105.866 1.00 83.11  ? 30  LEU A CB  1 
ATOM   4202 C  CG  . LEU B 1 30  ? 92.771  135.626 105.847 1.00 83.11  ? 30  LEU A CG  1 
ATOM   4203 C  CD1 . LEU B 1 30  ? 92.360  136.085 104.455 1.00 83.11  ? 30  LEU A CD1 1 
ATOM   4204 C  CD2 . LEU B 1 30  ? 91.760  136.074 106.885 1.00 83.11  ? 30  LEU A CD2 1 
ATOM   4205 N  N   . HIS B 1 31  ? 92.864  131.002 105.502 1.00 86.29  ? 31  HIS A N   1 
ATOM   4206 C  CA  . HIS B 1 31  ? 93.467  129.820 104.883 1.00 86.29  ? 31  HIS A CA  1 
ATOM   4207 C  C   . HIS B 1 31  ? 94.488  130.229 103.825 1.00 86.29  ? 31  HIS A C   1 
ATOM   4208 O  O   . HIS B 1 31  ? 94.553  129.662 102.733 1.00 86.29  ? 31  HIS A O   1 
ATOM   4209 C  CB  . HIS B 1 31  ? 92.398  128.899 104.291 1.00 86.29  ? 31  HIS A CB  1 
ATOM   4210 C  CG  . HIS B 1 31  ? 92.884  127.510 104.012 1.00 86.29  ? 31  HIS A CG  1 
ATOM   4211 N  ND1 . HIS B 1 31  ? 93.445  126.708 104.982 1.00 86.29  ? 31  HIS A ND1 1 
ATOM   4212 C  CD2 . HIS B 1 31  ? 92.891  126.781 102.871 1.00 86.29  ? 31  HIS A CD2 1 
ATOM   4213 C  CE1 . HIS B 1 31  ? 93.778  125.545 104.451 1.00 86.29  ? 31  HIS A CE1 1 
ATOM   4214 N  NE2 . HIS B 1 31  ? 93.453  125.564 103.171 1.00 86.29  ? 31  HIS A NE2 1 
ATOM   4215 N  N   . THR B 1 32  ? 95.292  131.235 104.157 1.00 86.78  ? 32  THR A N   1 
ATOM   4216 C  CA  . THR B 1 32  ? 96.252  131.821 103.236 1.00 86.78  ? 32  THR A CA  1 
ATOM   4217 C  C   . THR B 1 32  ? 97.630  131.813 103.878 1.00 86.78  ? 32  THR A C   1 
ATOM   4218 O  O   . THR B 1 32  ? 97.772  132.132 105.062 1.00 86.78  ? 32  THR A O   1 
ATOM   4219 C  CB  . THR B 1 32  ? 95.846  133.254 102.865 1.00 86.78  ? 32  THR A CB  1 
ATOM   4220 O  OG1 . THR B 1 32  ? 94.538  133.244 102.281 1.00 86.78  ? 32  THR A OG1 1 
ATOM   4221 C  CG2 . THR B 1 32  ? 96.823  133.853 101.874 1.00 86.78  ? 32  THR A CG2 1 
ATOM   4222 N  N   . LYS B 1 33  ? 98.645  131.442 103.092 1.00 86.80  ? 33  LYS A N   1 
ATOM   4223 C  CA  . LYS B 1 33  ? 100.006 131.394 103.619 1.00 86.80  ? 33  LYS A CA  1 
ATOM   4224 C  C   . LYS B 1 33  ? 100.483 132.776 104.048 1.00 86.80  ? 33  LYS A C   1 
ATOM   4225 O  O   . LYS B 1 33  ? 101.253 132.903 105.008 1.00 86.80  ? 33  LYS A O   1 
ATOM   4226 C  CB  . LYS B 1 33  ? 100.952 130.797 102.579 1.00 86.80  ? 33  LYS A CB  1 
ATOM   4227 C  CG  . LYS B 1 33  ? 100.819 129.293 102.422 1.00 86.80  ? 33  LYS A CG  1 
ATOM   4228 C  CD  . LYS B 1 33  ? 101.879 128.741 101.487 1.00 86.80  ? 33  LYS A CD  1 
ATOM   4229 C  CE  . LYS B 1 33  ? 101.697 127.250 101.271 1.00 86.80  ? 33  LYS A CE  1 
ATOM   4230 N  NZ  . LYS B 1 33  ? 101.998 126.476 102.506 1.00 86.80  ? 33  LYS A NZ  1 
ATOM   4231 N  N   . GLU B 1 34  ? 100.034 133.823 103.351 1.00 91.40  ? 34  GLU A N   1 
ATOM   4232 C  CA  . GLU B 1 34  ? 100.395 135.181 103.742 1.00 91.40  ? 34  GLU A CA  1 
ATOM   4233 C  C   . GLU B 1 34  ? 99.920  135.504 105.151 1.00 91.40  ? 34  GLU A C   1 
ATOM   4234 O  O   . GLU B 1 34  ? 100.649 136.138 105.920 1.00 91.40  ? 34  GLU A O   1 
ATOM   4235 C  CB  . GLU B 1 34  ? 99.819  136.185 102.744 1.00 91.40  ? 34  GLU A CB  1 
ATOM   4236 C  CG  . GLU B 1 34  ? 100.471 136.158 101.370 1.00 91.40  ? 34  GLU A CG  1 
ATOM   4237 C  CD  . GLU B 1 34  ? 99.876  135.112 100.444 1.00 91.40  ? 34  GLU A CD  1 
ATOM   4238 O  OE1 . GLU B 1 34  ? 99.514  135.465 99.302  1.00 91.40  ? 34  GLU A OE1 1 
ATOM   4239 O  OE2 . GLU B 1 34  ? 99.794  133.933 100.847 1.00 91.40  ? 34  GLU A OE2 1 
ATOM   4240 N  N   . ALA B 1 35  ? 98.710  135.080 105.508 1.00 85.20  ? 35  ALA A N   1 
ATOM   4241 C  CA  . ALA B 1 35  ? 98.212  135.282 106.862 1.00 85.20  ? 35  ALA A CA  1 
ATOM   4242 C  C   . ALA B 1 35  ? 98.802  134.292 107.853 1.00 85.20  ? 35  ALA A C   1 
ATOM   4243 O  O   . ALA B 1 35  ? 99.000  134.640 109.023 1.00 85.20  ? 35  ALA A O   1 
ATOM   4244 C  CB  . ALA B 1 35  ? 96.685  135.179 106.886 1.00 85.20  ? 35  ALA A CB  1 
ATOM   4245 N  N   . GLU B 1 36  ? 99.095  133.067 107.411 1.00 85.04  ? 36  GLU A N   1 
ATOM   4246 C  CA  . GLU B 1 36  ? 99.646  132.067 108.318 1.00 85.04  ? 36  GLU A CA  1 
ATOM   4247 C  C   . GLU B 1 36  ? 101.074 132.401 108.732 1.00 85.04  ? 36  GLU A C   1 
ATOM   4248 O  O   . GLU B 1 36  ? 101.483 132.073 109.851 1.00 85.04  ? 36  GLU A O   1 
ATOM   4249 C  CB  . GLU B 1 36  ? 99.574  130.684 107.672 1.00 85.04  ? 36  GLU A CB  1 
ATOM   4250 C  CG  . GLU B 1 36  ? 98.164  130.113 107.626 1.00 85.04  ? 36  GLU A CG  1 
ATOM   4251 C  CD  . GLU B 1 36  ? 98.012  128.993 106.617 1.00 85.04  ? 36  GLU A CD  1 
ATOM   4252 O  OE1 . GLU B 1 36  ? 98.987  128.245 106.402 1.00 85.04  ? 36  GLU A OE1 1 
ATOM   4253 O  OE2 . GLU B 1 36  ? 96.913  128.859 106.040 1.00 85.04  ? 36  GLU A OE2 1 
ATOM   4254 N  N   . CYS B 1 37  ? 101.846 133.044 107.854 1.00 81.42  ? 37  CYS A N   1 
ATOM   4255 C  CA  . CYS B 1 37  ? 103.175 133.498 108.250 1.00 81.42  ? 37  CYS A CA  1 
ATOM   4256 C  C   . CYS B 1 37  ? 103.088 134.714 109.164 1.00 81.42  ? 37  CYS A C   1 
ATOM   4257 O  O   . CYS B 1 37  ? 103.874 134.847 110.112 1.00 81.42  ? 37  CYS A O   1 
ATOM   4258 C  CB  . CYS B 1 37  ? 104.014 133.813 107.014 1.00 81.42  ? 37  CYS A CB  1 
ATOM   4259 S  SG  . CYS B 1 37  ? 105.781 133.986 107.341 1.00 81.42  ? 37  CYS A SG  1 
ATOM   4260 N  N   . ALA B 1 38  ? 102.136 135.612 108.895 1.00 79.00  ? 38  ALA A N   1 
ATOM   4261 C  CA  . ALA B 1 38  ? 101.948 136.779 109.749 1.00 79.00  ? 38  ALA A CA  1 
ATOM   4262 C  C   . ALA B 1 38  ? 101.496 136.383 111.147 1.00 79.00  ? 38  ALA A C   1 
ATOM   4263 O  O   . ALA B 1 38  ? 101.856 137.048 112.122 1.00 79.00  ? 38  ALA A O   1 
ATOM   4264 C  CB  . ALA B 1 38  ? 100.941 137.738 109.117 1.00 79.00  ? 38  ALA A CB  1 
ATOM   4265 N  N   . TYR B 1 39  ? 100.706 135.316 111.263 1.00 71.99  ? 39  TYR A N   1 
ATOM   4266 C  CA  . TYR B 1 39  ? 100.308 134.820 112.576 1.00 71.99  ? 39  TYR A CA  1 
ATOM   4267 C  C   . TYR B 1 39  ? 101.527 134.434 113.407 1.00 71.99  ? 39  TYR A C   1 
ATOM   4268 O  O   . TYR B 1 39  ? 101.667 134.852 114.565 1.00 71.99  ? 39  TYR A O   1 
ATOM   4269 C  CB  . TYR B 1 39  ? 99.364  133.629 112.404 1.00 71.99  ? 39  TYR A CB  1 
ATOM   4270 C  CG  . TYR B 1 39  ? 99.124  132.819 113.655 1.00 71.99  ? 39  TYR A CG  1 
ATOM   4271 C  CD1 . TYR B 1 39  ? 98.284  133.283 114.653 1.00 71.99  ? 39  TYR A CD1 1 
ATOM   4272 C  CD2 . TYR B 1 39  ? 99.730  131.585 113.832 1.00 71.99  ? 39  TYR A CD2 1 
ATOM   4273 C  CE1 . TYR B 1 39  ? 98.056  132.544 115.795 1.00 71.99  ? 39  TYR A CE1 1 
ATOM   4274 C  CE2 . TYR B 1 39  ? 99.509  130.840 114.971 1.00 71.99  ? 39  TYR A CE2 1 
ATOM   4275 C  CZ  . TYR B 1 39  ? 98.671  131.325 115.950 1.00 71.99  ? 39  TYR A CZ  1 
ATOM   4276 O  OH  . TYR B 1 39  ? 98.446  130.588 117.089 1.00 71.99  ? 39  TYR A OH  1 
ATOM   4277 N  N   . THR B 1 40  ? 102.430 133.645 112.819 1.00 69.86  ? 40  THR A N   1 
ATOM   4278 C  CA  . THR B 1 40  ? 103.648 133.253 113.520 1.00 69.86  ? 40  THR A CA  1 
ATOM   4279 C  C   . THR B 1 40  ? 104.513 134.462 113.844 1.00 69.86  ? 40  THR A C   1 
ATOM   4280 O  O   . THR B 1 40  ? 105.072 134.557 114.943 1.00 69.86  ? 40  THR A O   1 
ATOM   4281 C  CB  . THR B 1 40  ? 104.438 132.250 112.682 1.00 69.86  ? 40  THR A CB  1 
ATOM   4282 O  OG1 . THR B 1 40  ? 103.602 131.135 112.352 1.00 69.86  ? 40  THR A OG1 1 
ATOM   4283 C  CG2 . THR B 1 40  ? 105.657 131.765 113.445 1.00 69.86  ? 40  THR A CG2 1 
ATOM   4284 N  N   . LEU B 1 41  ? 104.641 135.393 112.896 1.00 66.59  ? 41  LEU A N   1 
ATOM   4285 C  CA  . LEU B 1 41  ? 105.449 136.583 113.140 1.00 66.59  ? 41  LEU A CA  1 
ATOM   4286 C  C   . LEU B 1 41  ? 104.902 137.379 114.317 1.00 66.59  ? 41  LEU A C   1 
ATOM   4287 O  O   . LEU B 1 41  ? 105.656 137.800 115.201 1.00 66.59  ? 41  LEU A O   1 
ATOM   4288 C  CB  . LEU B 1 41  ? 105.505 137.446 111.879 1.00 66.59  ? 41  LEU A CB  1 
ATOM   4289 C  CG  . LEU B 1 41  ? 106.384 138.697 111.925 1.00 66.59  ? 41  LEU A CG  1 
ATOM   4290 C  CD1 . LEU B 1 41  ? 107.110 138.880 110.608 1.00 66.59  ? 41  LEU A CD1 1 
ATOM   4291 C  CD2 . LEU B 1 41  ? 105.555 139.930 112.236 1.00 66.59  ? 41  LEU A CD2 1 
ATOM   4292 N  N   . PHE B 1 42  ? 103.583 137.578 114.354 1.00 64.12  ? 42  PHE A N   1 
ATOM   4293 C  CA  . PHE B 1 42  ? 102.975 138.344 115.435 1.00 64.12  ? 42  PHE A CA  1 
ATOM   4294 C  C   . PHE B 1 42  ? 103.145 137.640 116.774 1.00 64.12  ? 42  PHE A C   1 
ATOM   4295 O  O   . PHE B 1 42  ? 103.473 138.281 117.779 1.00 64.12  ? 42  PHE A O   1 
ATOM   4296 C  CB  . PHE B 1 42  ? 101.493 138.577 115.143 1.00 64.12  ? 42  PHE A CB  1 
ATOM   4297 C  CG  . PHE B 1 42  ? 101.223 139.741 114.231 1.00 64.12  ? 42  PHE A CG  1 
ATOM   4298 C  CD1 . PHE B 1 42  ? 102.171 140.163 113.316 1.00 64.12  ? 42  PHE A CD1 1 
ATOM   4299 C  CD2 . PHE B 1 42  ? 100.010 140.406 114.283 1.00 64.12  ? 42  PHE A CD2 1 
ATOM   4300 C  CE1 . PHE B 1 42  ? 101.918 141.228 112.476 1.00 64.12  ? 42  PHE A CE1 1 
ATOM   4301 C  CE2 . PHE B 1 42  ? 99.752  141.471 113.446 1.00 64.12  ? 42  PHE A CE2 1 
ATOM   4302 C  CZ  . PHE B 1 42  ? 100.707 141.882 112.542 1.00 64.12  ? 42  PHE A CZ  1 
ATOM   4303 N  N   . VAL B 1 43  ? 102.933 136.322 116.808 1.00 60.55  ? 43  VAL A N   1 
ATOM   4304 C  CA  . VAL B 1 43  ? 103.054 135.587 118.067 1.00 60.55  ? 43  VAL A CA  1 
ATOM   4305 C  C   . VAL B 1 43  ? 104.485 135.657 118.591 1.00 60.55  ? 43  VAL A C   1 
ATOM   4306 O  O   . VAL B 1 43  ? 104.722 135.938 119.775 1.00 60.55  ? 43  VAL A O   1 
ATOM   4307 C  CB  . VAL B 1 43  ? 102.588 134.132 117.887 1.00 60.55  ? 43  VAL A CB  1 
ATOM   4308 C  CG1 . VAL B 1 43  ? 103.029 133.287 119.062 1.00 60.55  ? 43  VAL A CG1 1 
ATOM   4309 C  CG2 . VAL B 1 43  ? 101.081 134.082 117.741 1.00 60.55  ? 43  VAL A CG2 1 
ATOM   4310 N  N   . VAL B 1 44  ? 105.461 135.412 117.715 1.00 57.89  ? 44  VAL A N   1 
ATOM   4311 C  CA  . VAL B 1 44  ? 106.856 135.427 118.141 1.00 57.89  ? 44  VAL A CA  1 
ATOM   4312 C  C   . VAL B 1 44  ? 107.267 136.826 118.583 1.00 57.89  ? 44  VAL A C   1 
ATOM   4313 O  O   . VAL B 1 44  ? 107.971 136.989 119.586 1.00 57.89  ? 44  VAL A O   1 
ATOM   4314 C  CB  . VAL B 1 44  ? 107.762 134.890 117.019 1.00 57.89  ? 44  VAL A CB  1 
ATOM   4315 C  CG1 . VAL B 1 44  ? 109.222 135.084 117.377 1.00 57.89  ? 44  VAL A CG1 1 
ATOM   4316 C  CG2 . VAL B 1 44  ? 107.472 133.422 116.772 1.00 57.89  ? 44  VAL A CG2 1 
ATOM   4317 N  N   . ALA B 1 45  ? 106.837 137.857 117.851 1.00 55.21  ? 45  ALA A N   1 
ATOM   4318 C  CA  . ALA B 1 45  ? 107.179 139.222 118.234 1.00 55.21  ? 45  ALA A CA  1 
ATOM   4319 C  C   . ALA B 1 45  ? 106.575 139.587 119.584 1.00 55.21  ? 45  ALA A C   1 
ATOM   4320 O  O   . ALA B 1 45  ? 107.235 140.225 120.413 1.00 55.21  ? 45  ALA A O   1 
ATOM   4321 C  CB  . ALA B 1 45  ? 106.716 140.200 117.156 1.00 55.21  ? 45  ALA A CB  1 
ATOM   4322 N  N   . THR B 1 46  ? 105.320 139.199 119.823 1.00 54.15  ? 46  THR A N   1 
ATOM   4323 C  CA  . THR B 1 46  ? 104.695 139.494 121.107 1.00 54.15  ? 46  THR A CA  1 
ATOM   4324 C  C   . THR B 1 46  ? 105.423 138.794 122.245 1.00 54.15  ? 46  THR A C   1 
ATOM   4325 O  O   . THR B 1 46  ? 105.675 139.397 123.296 1.00 54.15  ? 46  THR A O   1 
ATOM   4326 C  CB  . THR B 1 46  ? 103.223 139.085 121.082 1.00 54.15  ? 46  THR A CB  1 
ATOM   4327 O  OG1 . THR B 1 46  ? 102.528 139.863 120.101 1.00 54.15  ? 46  THR A OG1 1 
ATOM   4328 C  CG2 . THR B 1 46  ? 102.587 139.313 122.441 1.00 54.15  ? 46  THR A CG2 1 
ATOM   4329 N  N   . PHE B 1 47  ? 105.782 137.522 122.050 1.00 52.41  ? 47  PHE A N   1 
ATOM   4330 C  CA  . PHE B 1 47  ? 106.502 136.807 123.099 1.00 52.41  ? 47  PHE A CA  1 
ATOM   4331 C  C   . PHE B 1 47  ? 107.884 137.401 123.339 1.00 52.41  ? 47  PHE A C   1 
ATOM   4332 O  O   . PHE B 1 47  ? 108.352 137.431 124.483 1.00 52.41  ? 47  PHE A O   1 
ATOM   4333 C  CB  . PHE B 1 47  ? 106.611 135.325 122.753 1.00 52.41  ? 47  PHE A CB  1 
ATOM   4334 C  CG  . PHE B 1 47  ? 105.322 134.573 122.898 1.00 52.41  ? 47  PHE A CG  1 
ATOM   4335 C  CD1 . PHE B 1 47  ? 104.254 135.130 123.577 1.00 52.41  ? 47  PHE A CD1 1 
ATOM   4336 C  CD2 . PHE B 1 47  ? 105.180 133.307 122.361 1.00 52.41  ? 47  PHE A CD2 1 
ATOM   4337 C  CE1 . PHE B 1 47  ? 103.069 134.441 123.711 1.00 52.41  ? 47  PHE A CE1 1 
ATOM   4338 C  CE2 . PHE B 1 47  ? 103.998 132.614 122.494 1.00 52.41  ? 47  PHE A CE2 1 
ATOM   4339 C  CZ  . PHE B 1 47  ? 102.941 133.182 123.170 1.00 52.41  ? 47  PHE A CZ  1 
ATOM   4340 N  N   . TRP B 1 48  ? 108.553 137.868 122.283 1.00 52.44  ? 48  TRP A N   1 
ATOM   4341 C  CA  . TRP B 1 48  ? 109.861 138.494 122.451 1.00 52.44  ? 48  TRP A CA  1 
ATOM   4342 C  C   . TRP B 1 48  ? 109.753 139.806 123.216 1.00 52.44  ? 48  TRP A C   1 
ATOM   4343 O  O   . TRP B 1 48  ? 110.525 140.059 124.147 1.00 52.44  ? 48  TRP A O   1 
ATOM   4344 C  CB  . TRP B 1 48  ? 110.511 138.726 121.088 1.00 52.44  ? 48  TRP A CB  1 
ATOM   4345 C  CG  . TRP B 1 48  ? 111.375 137.602 120.627 1.00 52.44  ? 48  TRP A CG  1 
ATOM   4346 C  CD1 . TRP B 1 48  ? 111.924 136.623 121.397 1.00 52.44  ? 48  TRP A CD1 1 
ATOM   4347 C  CD2 . TRP B 1 48  ? 111.795 137.340 119.285 1.00 52.44  ? 48  TRP A CD2 1 
ATOM   4348 N  NE1 . TRP B 1 48  ? 112.661 135.766 120.619 1.00 52.44  ? 48  TRP A NE1 1 
ATOM   4349 C  CE2 . TRP B 1 48  ? 112.596 136.185 119.317 1.00 52.44  ? 48  TRP A CE2 1 
ATOM   4350 C  CE3 . TRP B 1 48  ? 111.570 137.971 118.059 1.00 52.44  ? 48  TRP A CE3 1 
ATOM   4351 C  CZ2 . TRP B 1 48  ? 113.173 135.646 118.171 1.00 52.44  ? 48  TRP A CZ2 1 
ATOM   4352 C  CZ3 . TRP B 1 48  ? 112.143 137.434 116.923 1.00 52.44  ? 48  TRP A CZ3 1 
ATOM   4353 C  CH2 . TRP B 1 48  ? 112.935 136.284 116.987 1.00 52.44  ? 48  TRP A CH2 1 
ATOM   4354 N  N   . LEU B 1 49  ? 108.798 140.657 122.837 1.00 50.87  ? 49  LEU A N   1 
ATOM   4355 C  CA  . LEU B 1 49  ? 108.708 141.981 123.440 1.00 50.87  ? 49  LEU A CA  1 
ATOM   4356 C  C   . LEU B 1 49  ? 108.144 141.949 124.854 1.00 50.87  ? 49  LEU A C   1 
ATOM   4357 O  O   . LEU B 1 49  ? 108.529 142.786 125.676 1.00 50.87  ? 49  LEU A O   1 
ATOM   4358 C  CB  . LEU B 1 49  ? 107.860 142.902 122.564 1.00 50.87  ? 49  LEU A CB  1 
ATOM   4359 C  CG  . LEU B 1 49  ? 108.367 143.102 121.136 1.00 50.87  ? 49  LEU A CG  1 
ATOM   4360 C  CD1 . LEU B 1 49  ? 107.263 143.645 120.247 1.00 50.87  ? 49  LEU A CD1 1 
ATOM   4361 C  CD2 . LEU B 1 49  ? 109.575 144.020 121.121 1.00 50.87  ? 49  LEU A CD2 1 
ATOM   4362 N  N   . THR B 1 50  ? 107.250 141.010 125.164 1.00 52.17  ? 50  THR A N   1 
ATOM   4363 C  CA  . THR B 1 50  ? 106.650 140.958 126.490 1.00 52.17  ? 50  THR A CA  1 
ATOM   4364 C  C   . THR B 1 50  ? 107.420 140.071 127.459 1.00 52.17  ? 50  THR A C   1 
ATOM   4365 O  O   . THR B 1 50  ? 107.221 140.188 128.674 1.00 52.17  ? 50  THR A O   1 
ATOM   4366 C  CB  . THR B 1 50  ? 105.200 140.471 126.392 1.00 52.17  ? 50  THR A CB  1 
ATOM   4367 O  OG1 . THR B 1 50  ? 104.546 141.149 125.314 1.00 52.17  ? 50  THR A OG1 1 
ATOM   4368 C  CG2 . THR B 1 50  ? 104.444 140.781 127.673 1.00 52.17  ? 50  THR A CG2 1 
ATOM   4369 N  N   . GLU B 1 51  ? 108.307 139.212 126.955 1.00 57.00  ? 51  GLU A N   1 
ATOM   4370 C  CA  . GLU B 1 51  ? 109.083 138.282 127.776 1.00 57.00  ? 51  GLU A CA  1 
ATOM   4371 C  C   . GLU B 1 51  ? 108.153 137.363 128.572 1.00 57.00  ? 51  GLU A C   1 
ATOM   4372 O  O   . GLU B 1 51  ? 108.274 137.195 129.787 1.00 57.00  ? 51  GLU A O   1 
ATOM   4373 C  CB  . GLU B 1 51  ? 110.053 139.039 128.693 1.00 57.00  ? 51  GLU A CB  1 
ATOM   4374 C  CG  . GLU B 1 51  ? 111.089 138.169 129.394 1.00 57.00  ? 51  GLU A CG  1 
ATOM   4375 C  CD  . GLU B 1 51  ? 112.276 137.853 128.513 1.00 57.00  ? 51  GLU A CD  1 
ATOM   4376 O  OE1 . GLU B 1 51  ? 112.333 138.381 127.384 1.00 57.00  ? 51  GLU A OE1 1 
ATOM   4377 O  OE2 . GLU B 1 51  ? 113.154 137.080 128.951 1.00 57.00  ? 51  GLU A OE2 1 
ATOM   4378 N  N   . ALA B 1 52  ? 107.195 136.777 127.856 1.00 56.64  ? 52  ALA A N   1 
ATOM   4379 C  CA  . ALA B 1 52  ? 106.327 135.776 128.464 1.00 56.64  ? 52  ALA A CA  1 
ATOM   4380 C  C   . ALA B 1 52  ? 107.072 134.459 128.645 1.00 56.64  ? 52  ALA A C   1 
ATOM   4381 O  O   . ALA B 1 52  ? 106.972 133.811 129.690 1.00 56.64  ? 52  ALA A O   1 
ATOM   4382 C  CB  . ALA B 1 52  ? 105.071 135.584 127.613 1.00 56.64  ? 52  ALA A CB  1 
ATOM   4383 N  N   . LEU B 1 53  ? 107.821 134.054 127.640 1.00 54.56  ? 53  LEU A N   1 
ATOM   4384 C  CA  . LEU B 1 53  ? 108.713 132.911 127.700 1.00 54.56  ? 53  LEU A CA  1 
ATOM   4385 C  C   . LEU B 1 53  ? 110.152 133.361 127.509 1.00 54.56  ? 53  LEU A C   1 
ATOM   4386 O  O   . LEU B 1 53  ? 110.407 134.455 126.996 1.00 54.56  ? 53  LEU A O   1 
ATOM   4387 C  CB  . LEU B 1 53  ? 108.340 131.883 126.626 1.00 54.56  ? 53  LEU A CB  1 
ATOM   4388 C  CG  . LEU B 1 53  ? 106.855 131.572 126.450 1.00 54.56  ? 53  LEU A CG  1 
ATOM   4389 C  CD1 . LEU B 1 53  ? 106.653 130.579 125.321 1.00 54.56  ? 53  LEU A CD1 1 
ATOM   4390 C  CD2 . LEU B 1 53  ? 106.271 131.038 127.743 1.00 54.56  ? 53  LEU A CD2 1 
ATOM   4391 N  N   . PRO B 1 54  ? 111.127 132.551 127.925 1.00 57.24  ? 54  PRO A N   1 
ATOM   4392 C  CA  . PRO B 1 54  ? 112.527 132.904 127.671 1.00 57.24  ? 54  PRO A CA  1 
ATOM   4393 C  C   . PRO B 1 54  ? 112.781 133.093 126.183 1.00 57.24  ? 54  PRO A C   1 
ATOM   4394 O  O   . PRO B 1 54  ? 112.144 132.465 125.336 1.00 57.24  ? 54  PRO A O   1 
ATOM   4395 C  CB  . PRO B 1 54  ? 113.303 131.707 128.228 1.00 57.24  ? 54  PRO A CB  1 
ATOM   4396 C  CG  . PRO B 1 54  ? 112.410 131.143 129.272 1.00 57.24  ? 54  PRO A CG  1 
ATOM   4397 C  CD  . PRO B 1 54  ? 111.007 131.358 128.782 1.00 57.24  ? 54  PRO A CD  1 
ATOM   4398 N  N   . LEU B 1 55  ? 113.722 133.988 125.875 1.00 56.49  ? 55  LEU A N   1 
ATOM   4399 C  CA  . LEU B 1 55  ? 113.916 134.423 124.495 1.00 56.49  ? 55  LEU A CA  1 
ATOM   4400 C  C   . LEU B 1 55  ? 114.281 133.259 123.583 1.00 56.49  ? 55  LEU A C   1 
ATOM   4401 O  O   . LEU B 1 55  ? 113.821 133.194 122.438 1.00 56.49  ? 55  LEU A O   1 
ATOM   4402 C  CB  . LEU B 1 55  ? 114.987 135.509 124.440 1.00 56.49  ? 55  LEU A CB  1 
ATOM   4403 C  CG  . LEU B 1 55  ? 114.606 136.828 125.109 1.00 56.49  ? 55  LEU A CG  1 
ATOM   4404 C  CD1 . LEU B 1 55  ? 115.719 137.848 124.959 1.00 56.49  ? 55  LEU A CD1 1 
ATOM   4405 C  CD2 . LEU B 1 55  ? 113.312 137.353 124.516 1.00 56.49  ? 55  LEU A CD2 1 
ATOM   4406 N  N   . SER B 1 56  ? 115.113 132.334 124.064 1.00 55.95  ? 56  SER A N   1 
ATOM   4407 C  CA  . SER B 1 56  ? 115.449 131.167 123.256 1.00 55.95  ? 56  SER A CA  1 
ATOM   4408 C  C   . SER B 1 56  ? 114.235 130.270 123.049 1.00 55.95  ? 56  SER A C   1 
ATOM   4409 O  O   . SER B 1 56  ? 114.050 129.702 121.964 1.00 55.95  ? 56  SER A O   1 
ATOM   4410 C  CB  . SER B 1 56  ? 116.589 130.393 123.910 1.00 55.95  ? 56  SER A CB  1 
ATOM   4411 O  OG  . SER B 1 56  ? 117.648 131.266 124.259 1.00 55.95  ? 56  SER A OG  1 
ATOM   4412 N  N   . VAL B 1 57  ? 113.393 130.133 124.076 1.00 55.19  ? 57  VAL A N   1 
ATOM   4413 C  CA  . VAL B 1 57  ? 112.176 129.340 123.939 1.00 55.19  ? 57  VAL A CA  1 
ATOM   4414 C  C   . VAL B 1 57  ? 111.282 129.926 122.855 1.00 55.19  ? 57  VAL A C   1 
ATOM   4415 O  O   . VAL B 1 57  ? 110.732 129.198 122.020 1.00 55.19  ? 57  VAL A O   1 
ATOM   4416 C  CB  . VAL B 1 57  ? 111.443 129.250 125.290 1.00 55.19  ? 57  VAL A CB  1 
ATOM   4417 C  CG1 . VAL B 1 57  ? 110.174 128.429 125.151 1.00 55.19  ? 57  VAL A CG1 1 
ATOM   4418 C  CG2 . VAL B 1 57  ? 112.357 128.660 126.347 1.00 55.19  ? 57  VAL A CG2 1 
ATOM   4419 N  N   . THR B 1 58  ? 111.121 131.250 122.851 1.00 55.69  ? 58  THR A N   1 
ATOM   4420 C  CA  . THR B 1 58  ? 110.341 131.896 121.802 1.00 55.69  ? 58  THR A CA  1 
ATOM   4421 C  C   . THR B 1 58  ? 110.996 131.716 120.439 1.00 55.69  ? 58  THR A C   1 
ATOM   4422 O  O   . THR B 1 58  ? 110.312 131.459 119.442 1.00 55.69  ? 58  THR A O   1 
ATOM   4423 C  CB  . THR B 1 58  ? 110.162 133.379 122.119 1.00 55.69  ? 58  THR A CB  1 
ATOM   4424 O  OG1 . THR B 1 58  ? 109.399 133.524 123.323 1.00 55.69  ? 58  THR A OG1 1 
ATOM   4425 C  CG2 . THR B 1 58  ? 109.445 134.083 120.982 1.00 55.69  ? 58  THR A CG2 1 
ATOM   4426 N  N   . ALA B 1 59  ? 112.324 131.842 120.376 1.00 57.28  ? 59  ALA A N   1 
ATOM   4427 C  CA  . ALA B 1 59  ? 113.022 131.694 119.103 1.00 57.28  ? 59  ALA A CA  1 
ATOM   4428 C  C   . ALA B 1 59  ? 112.884 130.284 118.550 1.00 57.28  ? 59  ALA A C   1 
ATOM   4429 O  O   . ALA B 1 59  ? 113.010 130.076 117.338 1.00 57.28  ? 59  ALA A O   1 
ATOM   4430 C  CB  . ALA B 1 59  ? 114.496 132.058 119.268 1.00 57.28  ? 59  ALA A CB  1 
ATOM   4431 N  N   . LEU B 1 60  ? 112.645 129.303 119.420 1.00 59.28  ? 60  LEU A N   1 
ATOM   4432 C  CA  . LEU B 1 60  ? 112.407 127.945 118.947 1.00 59.28  ? 60  LEU A CA  1 
ATOM   4433 C  C   . LEU B 1 60  ? 111.037 127.785 118.296 1.00 59.28  ? 60  LEU A C   1 
ATOM   4434 O  O   . LEU B 1 60  ? 110.831 126.821 117.551 1.00 59.28  ? 60  LEU A O   1 
ATOM   4435 C  CB  . LEU B 1 60  ? 112.551 126.954 120.101 1.00 59.28  ? 60  LEU A CB  1 
ATOM   4436 C  CG  . LEU B 1 60  ? 113.979 126.707 120.583 1.00 59.28  ? 60  LEU A CG  1 
ATOM   4437 C  CD1 . LEU B 1 60  ? 113.978 126.124 121.984 1.00 59.28  ? 60  LEU A CD1 1 
ATOM   4438 C  CD2 . LEU B 1 60  ? 114.710 125.792 119.620 1.00 59.28  ? 60  LEU A CD2 1 
ATOM   4439 N  N   . LEU B 1 61  ? 110.102 128.700 118.560 1.00 64.56  ? 61  LEU A N   1 
ATOM   4440 C  CA  . LEU B 1 61  ? 108.747 128.565 118.026 1.00 64.56  ? 61  LEU A CA  1 
ATOM   4441 C  C   . LEU B 1 61  ? 108.679 128.568 116.502 1.00 64.56  ? 61  LEU A C   1 
ATOM   4442 O  O   . LEU B 1 61  ? 107.952 127.729 115.944 1.00 64.56  ? 61  LEU A O   1 
ATOM   4443 C  CB  . LEU B 1 61  ? 107.848 129.655 118.620 1.00 64.56  ? 61  LEU A CB  1 
ATOM   4444 C  CG  . LEU B 1 61  ? 107.449 129.479 120.085 1.00 64.56  ? 61  LEU A CG  1 
ATOM   4445 C  CD1 . LEU B 1 61  ? 106.191 130.269 120.390 1.00 64.56  ? 61  LEU A CD1 1 
ATOM   4446 C  CD2 . LEU B 1 61  ? 107.247 128.011 120.409 1.00 64.56  ? 61  LEU A CD2 1 
ATOM   4447 N  N   . PRO B 1 62  ? 109.366 129.457 115.773 1.00 68.05  ? 62  PRO A N   1 
ATOM   4448 C  CA  . PRO B 1 62  ? 109.241 129.433 114.306 1.00 68.05  ? 62  PRO A CA  1 
ATOM   4449 C  C   . PRO B 1 62  ? 109.681 128.128 113.671 1.00 68.05  ? 62  PRO A C   1 
ATOM   4450 O  O   . PRO B 1 62  ? 109.316 127.867 112.519 1.00 68.05  ? 62  PRO A O   1 
ATOM   4451 C  CB  . PRO B 1 62  ? 110.134 130.597 113.858 1.00 68.05  ? 62  PRO A CB  1 
ATOM   4452 C  CG  . PRO B 1 62  ? 110.152 131.512 115.011 1.00 68.05  ? 62  PRO A CG  1 
ATOM   4453 C  CD  . PRO B 1 62  ? 110.133 130.632 116.222 1.00 68.05  ? 62  PRO A CD  1 
ATOM   4454 N  N   . SER B 1 63  ? 110.460 127.303 114.368 1.00 68.26  ? 63  SER A N   1 
ATOM   4455 C  CA  . SER B 1 63  ? 110.824 126.002 113.826 1.00 68.26  ? 63  SER A CA  1 
ATOM   4456 C  C   . SER B 1 63  ? 109.722 124.966 114.002 1.00 68.26  ? 63  SER A C   1 
ATOM   4457 O  O   . SER B 1 63  ? 109.768 123.919 113.348 1.00 68.26  ? 63  SER A O   1 
ATOM   4458 C  CB  . SER B 1 63  ? 112.111 125.499 114.481 1.00 68.26  ? 63  SER A CB  1 
ATOM   4459 O  OG  . SER B 1 63  ? 113.201 126.350 114.176 1.00 68.26  ? 63  SER A OG  1 
ATOM   4460 N  N   . LEU B 1 64  ? 108.735 125.235 114.856 1.00 69.07  ? 64  LEU A N   1 
ATOM   4461 C  CA  . LEU B 1 64  ? 107.681 124.276 115.161 1.00 69.07  ? 64  LEU A CA  1 
ATOM   4462 C  C   . LEU B 1 64  ? 106.355 124.640 114.508 1.00 69.07  ? 64  LEU A C   1 
ATOM   4463 O  O   . LEU B 1 64  ? 105.789 123.834 113.766 1.00 69.07  ? 64  LEU A O   1 
ATOM   4464 C  CB  . LEU B 1 64  ? 107.495 124.165 116.677 1.00 69.07  ? 64  LEU A CB  1 
ATOM   4465 C  CG  . LEU B 1 64  ? 108.782 124.036 117.479 1.00 69.07  ? 64  LEU A CG  1 
ATOM   4466 C  CD1 . LEU B 1 64  ? 108.487 124.115 118.964 1.00 69.07  ? 64  LEU A CD1 1 
ATOM   4467 C  CD2 . LEU B 1 64  ? 109.447 122.725 117.122 1.00 69.07  ? 64  LEU A CD2 1 
ATOM   4468 N  N   . MET B 1 65  ? 105.838 125.838 114.777 1.00 76.24  ? 65  MET A N   1 
ATOM   4469 C  CA  . MET B 1 65  ? 104.506 126.198 114.308 1.00 76.24  ? 65  MET A CA  1 
ATOM   4470 C  C   . MET B 1 65  ? 104.489 126.558 112.829 1.00 76.24  ? 65  MET A C   1 
ATOM   4471 O  O   . MET B 1 65  ? 103.450 126.415 112.176 1.00 76.24  ? 65  MET A O   1 
ATOM   4472 C  CB  . MET B 1 65  ? 103.954 127.344 115.155 1.00 76.24  ? 65  MET A CB  1 
ATOM   4473 C  CG  . MET B 1 65  ? 104.661 128.666 114.961 1.00 76.24  ? 65  MET A CG  1 
ATOM   4474 S  SD  . MET B 1 65  ? 104.359 129.797 116.330 1.00 76.24  ? 65  MET A SD  1 
ATOM   4475 C  CE  . MET B 1 65  ? 102.570 129.806 116.374 1.00 76.24  ? 65  MET A CE  1 
ATOM   4476 N  N   . LEU B 1 66  ? 105.609 127.031 112.287 1.00 76.53  ? 66  LEU A N   1 
ATOM   4477 C  CA  . LEU B 1 66  ? 105.663 127.337 110.859 1.00 76.53  ? 66  LEU A CA  1 
ATOM   4478 C  C   . LEU B 1 66  ? 105.474 126.103 109.983 1.00 76.53  ? 66  LEU A C   1 
ATOM   4479 O  O   . LEU B 1 66  ? 104.662 126.165 109.043 1.00 76.53  ? 66  LEU A O   1 
ATOM   4480 C  CB  . LEU B 1 66  ? 106.973 128.065 110.539 1.00 76.53  ? 66  LEU A CB  1 
ATOM   4481 C  CG  . LEU B 1 66  ? 107.054 128.854 109.235 1.00 76.53  ? 66  LEU A CG  1 
ATOM   4482 C  CD1 . LEU B 1 66  ? 106.117 130.048 109.281 1.00 76.53  ? 66  LEU A CD1 1 
ATOM   4483 C  CD2 . LEU B 1 66  ? 108.483 129.301 108.981 1.00 76.53  ? 66  LEU A CD2 1 
ATOM   4484 N  N   . PRO B 1 67  ? 106.162 124.976 110.207 1.00 77.61  ? 67  PRO A N   1 
ATOM   4485 C  CA  . PRO B 1 67  ? 105.914 123.796 109.360 1.00 77.61  ? 67  PRO A CA  1 
ATOM   4486 C  C   . PRO B 1 67  ? 104.494 123.262 109.440 1.00 77.61  ? 67  PRO A C   1 
ATOM   4487 O  O   . PRO B 1 67  ? 104.049 122.603 108.493 1.00 77.61  ? 67  PRO A O   1 
ATOM   4488 C  CB  . PRO B 1 67  ? 106.927 122.768 109.881 1.00 77.61  ? 67  PRO A CB  1 
ATOM   4489 C  CG  . PRO B 1 67  ? 107.990 123.578 110.515 1.00 77.61  ? 67  PRO A CG  1 
ATOM   4490 C  CD  . PRO B 1 67  ? 107.279 124.733 111.138 1.00 77.61  ? 67  PRO A CD  1 
ATOM   4491 N  N   . MET B 1 68  ? 103.769 123.516 110.531 1.00 77.27  ? 68  MET A N   1 
ATOM   4492 C  CA  . MET B 1 68  ? 102.386 123.061 110.618 1.00 77.27  ? 68  MET A CA  1 
ATOM   4493 C  C   . MET B 1 68  ? 101.491 123.735 109.590 1.00 77.27  ? 68  MET A C   1 
ATOM   4494 O  O   . MET B 1 68  ? 100.463 123.164 109.213 1.00 77.27  ? 68  MET A O   1 
ATOM   4495 C  CB  . MET B 1 68  ? 101.832 123.308 112.020 1.00 77.27  ? 68  MET A CB  1 
ATOM   4496 C  CG  . MET B 1 68  ? 102.824 123.051 113.134 1.00 77.27  ? 68  MET A CG  1 
ATOM   4497 S  SD  . MET B 1 68  ? 102.892 121.322 113.628 1.00 77.27  ? 68  MET A SD  1 
ATOM   4498 C  CE  . MET B 1 68  ? 101.161 120.987 113.932 1.00 77.27  ? 68  MET A CE  1 
ATOM   4499 N  N   . PHE B 1 69  ? 101.856 124.928 109.130 1.00 80.22  ? 69  PHE A N   1 
ATOM   4500 C  CA  . PHE B 1 69  ? 101.056 125.679 108.173 1.00 80.22  ? 69  PHE A CA  1 
ATOM   4501 C  C   . PHE B 1 69  ? 101.420 125.377 106.727 1.00 80.22  ? 69  PHE A C   1 
ATOM   4502 O  O   . PHE B 1 69  ? 100.823 125.962 105.818 1.00 80.22  ? 69  PHE A O   1 
ATOM   4503 C  CB  . PHE B 1 69  ? 101.205 127.181 108.432 1.00 80.22  ? 69  PHE A CB  1 
ATOM   4504 C  CG  . PHE B 1 69  ? 100.655 127.625 109.754 1.00 80.22  ? 69  PHE A CG  1 
ATOM   4505 C  CD1 . PHE B 1 69  ? 99.372  127.281 110.135 1.00 80.22  ? 69  PHE A CD1 1 
ATOM   4506 C  CD2 . PHE B 1 69  ? 101.423 128.385 110.616 1.00 80.22  ? 69  PHE A CD2 1 
ATOM   4507 C  CE1 . PHE B 1 69  ? 98.865  127.687 111.352 1.00 80.22  ? 69  PHE A CE1 1 
ATOM   4508 C  CE2 . PHE B 1 69  ? 100.921 128.794 111.833 1.00 80.22  ? 69  PHE A CE2 1 
ATOM   4509 C  CZ  . PHE B 1 69  ? 99.641  128.444 112.202 1.00 80.22  ? 69  PHE A CZ  1 
ATOM   4510 N  N   . GLY B 1 70  ? 102.374 124.479 106.490 1.00 83.82  ? 70  GLY A N   1 
ATOM   4511 C  CA  . GLY B 1 70  ? 102.853 124.209 105.153 1.00 83.82  ? 70  GLY A CA  1 
ATOM   4512 C  C   . GLY B 1 70  ? 104.078 124.991 104.743 1.00 83.82  ? 70  GLY A C   1 
ATOM   4513 O  O   . GLY B 1 70  ? 104.655 124.698 103.688 1.00 83.82  ? 70  GLY A O   1 
ATOM   4514 N  N   . ILE B 1 71  ? 104.497 125.974 105.533 1.00 86.53  ? 71  ILE A N   1 
ATOM   4515 C  CA  . ILE B 1 71  ? 105.710 126.733 105.259 1.00 86.53  ? 71  ILE A CA  1 
ATOM   4516 C  C   . ILE B 1 71  ? 106.863 126.083 106.008 1.00 86.53  ? 71  ILE A C   1 
ATOM   4517 O  O   . ILE B 1 71  ? 106.841 125.988 107.240 1.00 86.53  ? 71  ILE A O   1 
ATOM   4518 C  CB  . ILE B 1 71  ? 105.544 128.204 105.674 1.00 86.53  ? 71  ILE A CB  1 
ATOM   4519 C  CG1 . ILE B 1 71  ? 104.307 128.810 105.011 1.00 86.53  ? 71  ILE A CG1 1 
ATOM   4520 C  CG2 . ILE B 1 71  ? 106.787 128.998 105.316 1.00 86.53  ? 71  ILE A CG2 1 
ATOM   4521 C  CD1 . ILE B 1 71  ? 104.165 130.298 105.234 1.00 86.53  ? 71  ILE A CD1 1 
ATOM   4522 N  N   . MET B 1 72  ? 107.874 125.645 105.273 1.00 95.19  ? 72  MET A N   1 
ATOM   4523 C  CA  . MET B 1 72  ? 109.014 124.950 105.846 1.00 95.19  ? 72  MET A CA  1 
ATOM   4524 C  C   . MET B 1 72  ? 110.284 125.703 105.491 1.00 95.19  ? 72  MET A C   1 
ATOM   4525 O  O   . MET B 1 72  ? 110.315 126.450 104.506 1.00 95.19  ? 72  MET A O   1 
ATOM   4526 C  CB  . MET B 1 72  ? 109.107 123.502 105.346 1.00 95.19  ? 72  MET A CB  1 
ATOM   4527 C  CG  . MET B 1 72  ? 108.162 122.535 106.039 1.00 95.19  ? 72  MET A CG  1 
ATOM   4528 S  SD  . MET B 1 72  ? 106.451 122.694 105.500 1.00 95.19  ? 72  MET A SD  1 
ATOM   4529 C  CE  . MET B 1 72  ? 106.433 121.587 104.092 1.00 95.19  ? 72  MET A CE  1 
ATOM   4530 N  N   . PRO B 1 73  ? 111.338 125.549 106.290 1.00 101.12 ? 73  PRO A N   1 
ATOM   4531 C  CA  . PRO B 1 73  ? 112.631 126.141 105.930 1.00 101.12 ? 73  PRO A CA  1 
ATOM   4532 C  C   . PRO B 1 73  ? 113.072 125.689 104.546 1.00 101.12 ? 73  PRO A C   1 
ATOM   4533 O  O   . PRO B 1 73  ? 112.934 124.519 104.180 1.00 101.12 ? 73  PRO A O   1 
ATOM   4534 C  CB  . PRO B 1 73  ? 113.579 125.621 107.018 1.00 101.12 ? 73  PRO A CB  1 
ATOM   4535 C  CG  . PRO B 1 73  ? 112.717 124.954 108.060 1.00 101.12 ? 73  PRO A CG  1 
ATOM   4536 C  CD  . PRO B 1 73  ? 111.283 125.158 107.706 1.00 101.12 ? 73  PRO A CD  1 
ATOM   4537 N  N   . SER B 1 74  ? 113.607 126.629 103.773 1.00 108.97 ? 74  SER A N   1 
ATOM   4538 C  CA  . SER B 1 74  ? 113.985 126.361 102.395 1.00 108.97 ? 74  SER A CA  1 
ATOM   4539 C  C   . SER B 1 74  ? 115.347 126.981 102.124 1.00 108.97 ? 74  SER A C   1 
ATOM   4540 O  O   . SER B 1 74  ? 116.059 127.394 103.043 1.00 108.97 ? 74  SER A O   1 
ATOM   4541 C  CB  . SER B 1 74  ? 112.937 126.897 101.414 1.00 108.97 ? 74  SER A CB  1 
ATOM   4542 O  OG  . SER B 1 74  ? 112.889 128.313 101.444 1.00 108.97 ? 74  SER A OG  1 
ATOM   4543 N  N   . LYS B 1 75  ? 115.706 127.017 100.839 1.00 119.26 ? 75  LYS A N   1 
ATOM   4544 C  CA  . LYS B 1 75  ? 116.961 127.595 100.369 1.00 119.26 ? 75  LYS A CA  1 
ATOM   4545 C  C   . LYS B 1 75  ? 118.157 126.833 100.925 1.00 119.26 ? 75  LYS A C   1 
ATOM   4546 O  O   . LYS B 1 75  ? 118.008 125.726 101.454 1.00 119.26 ? 75  LYS A O   1 
ATOM   4547 C  CB  . LYS B 1 75  ? 117.051 129.079 100.736 1.00 119.26 ? 75  LYS A CB  1 
ATOM   4548 N  N   . LYS B 1 76  ? 119.344 127.416 100.810 1.00 127.39 ? 76  LYS A N   1 
ATOM   4549 C  CA  . LYS B 1 76  ? 120.571 126.769 101.259 1.00 127.39 ? 76  LYS A CA  1 
ATOM   4550 C  C   . LYS B 1 76  ? 121.485 127.845 101.836 1.00 127.39 ? 76  LYS A C   1 
ATOM   4551 O  O   . LYS B 1 76  ? 121.073 128.987 102.067 1.00 127.39 ? 76  LYS A O   1 
ATOM   4552 C  CB  . LYS B 1 76  ? 121.214 125.983 100.107 1.00 127.39 ? 76  LYS A CB  1 
ATOM   4553 C  CG  . LYS B 1 76  ? 121.665 126.851 98.945  1.00 127.39 ? 76  LYS A CG  1 
ATOM   4554 C  CD  . LYS B 1 76  ? 122.217 126.008 97.808  1.00 127.39 ? 76  LYS A CD  1 
ATOM   4555 C  CE  . LYS B 1 76  ? 122.693 126.879 96.658  1.00 127.39 ? 76  LYS A CE  1 
ATOM   4556 N  NZ  . LYS B 1 76  ? 121.564 127.593 96.000  1.00 127.39 ? 76  LYS A NZ  1 
ATOM   4557 N  N   . VAL B 1 77  ? 122.742 127.481 102.078 1.00 132.25 ? 77  VAL A N   1 
ATOM   4558 C  CA  . VAL B 1 77  ? 123.718 128.399 102.654 1.00 132.25 ? 77  VAL A CA  1 
ATOM   4559 C  C   . VAL B 1 77  ? 125.097 127.975 102.162 1.00 132.25 ? 77  VAL A C   1 
ATOM   4560 O  O   . VAL B 1 77  ? 125.253 126.894 101.588 1.00 132.25 ? 77  VAL A O   1 
ATOM   4561 C  CB  . VAL B 1 77  ? 123.627 128.397 104.194 1.00 132.25 ? 77  VAL A CB  1 
ATOM   4562 C  CG1 . VAL B 1 77  ? 124.049 127.043 104.755 1.00 132.25 ? 77  VAL A CG1 1 
ATOM   4563 C  CG2 . VAL B 1 77  ? 124.416 129.549 104.817 1.00 132.25 ? 77  VAL A CG2 1 
ATOM   4564 N  N   . ALA B 1 78  ? 126.103 128.827 102.362 1.00 134.24 ? 78  ALA A N   1 
ATOM   4565 C  CA  . ALA B 1 78  ? 127.497 128.497 102.073 1.00 134.24 ? 78  ALA A CA  1 
ATOM   4566 C  C   . ALA B 1 78  ? 128.310 128.640 103.360 1.00 134.24 ? 78  ALA A C   1 
ATOM   4567 O  O   . ALA B 1 78  ? 129.407 129.198 103.385 1.00 134.24 ? 78  ALA A O   1 
ATOM   4568 C  CB  . ALA B 1 78  ? 128.059 129.375 100.958 1.00 134.24 ? 78  ALA A CB  1 
ATOM   4569 N  N   . SER B 1 79  ? 127.747 128.116 104.450 1.00 130.31 ? 79  SER A N   1 
ATOM   4570 C  CA  . SER B 1 79  ? 128.315 128.353 105.773 1.00 130.31 ? 79  SER A CA  1 
ATOM   4571 C  C   . SER B 1 79  ? 129.597 127.559 105.992 1.00 130.31 ? 79  SER A C   1 
ATOM   4572 O  O   . SER B 1 79  ? 130.448 127.964 106.794 1.00 130.31 ? 79  SER A O   1 
ATOM   4573 C  CB  . SER B 1 79  ? 127.287 128.008 106.850 1.00 130.31 ? 79  SER A CB  1 
ATOM   4574 O  OG  . SER B 1 79  ? 127.719 128.443 108.128 1.00 130.31 ? 79  SER A OG  1 
ATOM   4575 N  N   . ALA B 1 80  ? 129.753 126.433 105.297 1.00 123.41 ? 80  ALA A N   1 
ATOM   4576 C  CA  . ALA B 1 80  ? 130.832 125.470 105.565 1.00 123.41 ? 80  ALA A CA  1 
ATOM   4577 C  C   . ALA B 1 80  ? 130.646 125.037 107.018 1.00 123.41 ? 80  ALA A C   1 
ATOM   4578 O  O   . ALA B 1 80  ? 129.592 124.468 107.347 1.00 123.41 ? 80  ALA A O   1 
ATOM   4579 C  CB  . ALA B 1 80  ? 132.193 126.063 105.215 1.00 123.41 ? 80  ALA A CB  1 
ATOM   4580 N  N   . TYR B 1 81  ? 131.607 125.272 107.909 1.00 102.55 ? 81  TYR A N   1 
ATOM   4581 C  CA  . TYR B 1 81  ? 131.375 125.070 109.330 1.00 102.55 ? 81  TYR A CA  1 
ATOM   4582 C  C   . TYR B 1 81  ? 132.188 126.079 110.126 1.00 102.55 ? 81  TYR A C   1 
ATOM   4583 O  O   . TYR B 1 81  ? 133.177 126.630 109.634 1.00 102.55 ? 81  TYR A O   1 
ATOM   4584 C  CB  . TYR B 1 81  ? 131.723 123.648 109.785 1.00 102.55 ? 81  TYR A CB  1 
ATOM   4585 C  CG  . TYR B 1 81  ? 131.002 123.252 111.053 1.00 102.55 ? 81  TYR A CG  1 
ATOM   4586 C  CD1 . TYR B 1 81  ? 129.683 122.820 111.014 1.00 102.55 ? 81  TYR A CD1 1 
ATOM   4587 C  CD2 . TYR B 1 81  ? 131.624 123.342 112.289 1.00 102.55 ? 81  TYR A CD2 1 
ATOM   4588 C  CE1 . TYR B 1 81  ? 129.012 122.466 112.168 1.00 102.55 ? 81  TYR A CE1 1 
ATOM   4589 C  CE2 . TYR B 1 81  ? 130.959 122.999 113.448 1.00 102.55 ? 81  TYR A CE2 1 
ATOM   4590 C  CZ  . TYR B 1 81  ? 129.655 122.557 113.382 1.00 102.55 ? 81  TYR A CZ  1 
ATOM   4591 O  OH  . TYR B 1 81  ? 128.993 122.209 114.536 1.00 102.55 ? 81  TYR A OH  1 
ATOM   4592 N  N   . PHE B 1 82  ? 131.756 126.309 111.359 1.00 90.29  ? 82  PHE A N   1 
ATOM   4593 C  CA  . PHE B 1 82  ? 132.337 127.291 112.279 1.00 90.29  ? 82  PHE A CA  1 
ATOM   4594 C  C   . PHE B 1 82  ? 132.316 128.672 111.619 1.00 90.29  ? 82  PHE A C   1 
ATOM   4595 O  O   . PHE B 1 82  ? 131.657 128.878 110.596 1.00 90.29  ? 82  PHE A O   1 
ATOM   4596 C  CB  . PHE B 1 82  ? 133.713 126.825 112.723 1.00 90.29  ? 82  PHE A CB  1 
ATOM   4597 C  CG  . PHE B 1 82  ? 133.694 125.920 113.920 1.00 90.29  ? 82  PHE A CG  1 
ATOM   4598 C  CD1 . PHE B 1 82  ? 134.547 124.833 113.997 1.00 90.29  ? 82  PHE A CD1 1 
ATOM   4599 C  CD2 . PHE B 1 82  ? 132.828 126.161 114.972 1.00 90.29  ? 82  PHE A CD2 1 
ATOM   4600 C  CE1 . PHE B 1 82  ? 134.534 124.001 115.100 1.00 90.29  ? 82  PHE A CE1 1 
ATOM   4601 C  CE2 . PHE B 1 82  ? 132.810 125.332 116.077 1.00 90.29  ? 82  PHE A CE2 1 
ATOM   4602 C  CZ  . PHE B 1 82  ? 133.664 124.251 116.141 1.00 90.29  ? 82  PHE A CZ  1 
ATOM   4603 N  N   . LYS B 1 83  ? 133.049 129.619 112.198 1.00 79.94  ? 83  LYS A N   1 
ATOM   4604 C  CA  . LYS B 1 83  ? 133.129 130.982 111.693 1.00 79.94  ? 83  LYS A CA  1 
ATOM   4605 C  C   . LYS B 1 83  ? 134.413 131.605 112.215 1.00 79.94  ? 83  LYS A C   1 
ATOM   4606 O  O   . LYS B 1 83  ? 135.157 130.994 112.985 1.00 79.94  ? 83  LYS A O   1 
ATOM   4607 C  CB  . LYS B 1 83  ? 131.921 131.829 112.119 1.00 79.94  ? 83  LYS A CB  1 
ATOM   4608 C  CG  . LYS B 1 83  ? 130.669 131.666 111.273 1.00 79.94  ? 83  LYS A CG  1 
ATOM   4609 C  CD  . LYS B 1 83  ? 129.461 132.268 111.967 1.00 79.94  ? 83  LYS A CD  1 
ATOM   4610 C  CE  . LYS B 1 83  ? 128.169 131.653 111.461 1.00 79.94  ? 83  LYS A CE  1 
ATOM   4611 N  NZ  . LYS B 1 83  ? 127.000 132.072 112.281 1.00 79.94  ? 83  LYS A NZ  1 
ATOM   4612 N  N   . ASP B 1 84  ? 134.665 132.837 111.780 1.00 76.89  ? 84  ASP A N   1 
ATOM   4613 C  CA  . ASP B 1 84  ? 135.720 133.646 112.371 1.00 76.89  ? 84  ASP A CA  1 
ATOM   4614 C  C   . ASP B 1 84  ? 135.260 134.354 113.637 1.00 76.89  ? 84  ASP A C   1 
ATOM   4615 O  O   . ASP B 1 84  ? 136.096 134.902 114.362 1.00 76.89  ? 84  ASP A O   1 
ATOM   4616 C  CB  . ASP B 1 84  ? 136.221 134.676 111.355 1.00 76.89  ? 84  ASP A CB  1 
ATOM   4617 C  CG  . ASP B 1 84  ? 137.681 135.031 111.555 1.00 76.89  ? 84  ASP A CG  1 
ATOM   4618 O  OD1 . ASP B 1 84  ? 138.276 135.631 110.635 1.00 76.89  ? 84  ASP A OD1 1 
ATOM   4619 O  OD2 . ASP B 1 84  ? 138.235 134.712 112.626 1.00 76.89  ? 84  ASP A OD2 1 
ATOM   4620 N  N   . PHE B 1 85  ? 133.957 134.346 113.918 1.00 69.26  ? 85  PHE A N   1 
ATOM   4621 C  CA  . PHE B 1 85  ? 133.402 135.033 115.077 1.00 69.26  ? 85  PHE A CA  1 
ATOM   4622 C  C   . PHE B 1 85  ? 133.195 134.103 116.266 1.00 69.26  ? 85  PHE A C   1 
ATOM   4623 O  O   . PHE B 1 85  ? 133.378 134.522 117.413 1.00 69.26  ? 85  PHE A O   1 
ATOM   4624 C  CB  . PHE B 1 85  ? 132.073 135.693 114.710 1.00 69.26  ? 85  PHE A CB  1 
ATOM   4625 C  CG  . PHE B 1 85  ? 131.407 136.385 115.860 1.00 69.26  ? 85  PHE A CG  1 
ATOM   4626 C  CD1 . PHE B 1 85  ? 131.976 137.509 116.430 1.00 69.26  ? 85  PHE A CD1 1 
ATOM   4627 C  CD2 . PHE B 1 85  ? 130.221 135.901 116.384 1.00 69.26  ? 85  PHE A CD2 1 
ATOM   4628 C  CE1 . PHE B 1 85  ? 131.368 138.145 117.493 1.00 69.26  ? 85  PHE A CE1 1 
ATOM   4629 C  CE2 . PHE B 1 85  ? 129.609 136.532 117.448 1.00 69.26  ? 85  PHE A CE2 1 
ATOM   4630 C  CZ  . PHE B 1 85  ? 130.183 137.656 118.002 1.00 69.26  ? 85  PHE A CZ  1 
ATOM   4631 N  N   . HIS B 1 86  ? 132.803 132.852 116.016 1.00 69.45  ? 86  HIS A N   1 
ATOM   4632 C  CA  . HIS B 1 86  ? 132.573 131.920 117.114 1.00 69.45  ? 86  HIS A CA  1 
ATOM   4633 C  C   . HIS B 1 86  ? 133.853 131.665 117.898 1.00 69.45  ? 86  HIS A C   1 
ATOM   4634 O  O   . HIS B 1 86  ? 133.833 131.604 119.133 1.00 69.45  ? 86  HIS A O   1 
ATOM   4635 C  CB  . HIS B 1 86  ? 132.002 130.610 116.576 1.00 69.45  ? 86  HIS A CB  1 
ATOM   4636 C  CG  . HIS B 1 86  ? 130.534 130.663 116.287 1.00 69.45  ? 86  HIS A CG  1 
ATOM   4637 N  ND1 . HIS B 1 86  ? 130.027 131.116 115.089 1.00 69.45  ? 86  HIS A ND1 1 
ATOM   4638 C  CD2 . HIS B 1 86  ? 129.464 130.314 117.040 1.00 69.45  ? 86  HIS A CD2 1 
ATOM   4639 C  CE1 . HIS B 1 86  ? 128.708 131.048 115.117 1.00 69.45  ? 86  HIS A CE1 1 
ATOM   4640 N  NE2 . HIS B 1 86  ? 128.341 130.564 116.289 1.00 69.45  ? 86  HIS A NE2 1 
ATOM   4641 N  N   . LEU B 1 87  ? 134.978 131.516 117.197 1.00 64.66  ? 87  LEU A N   1 
ATOM   4642 C  CA  . LEU B 1 87  ? 136.252 131.282 117.870 1.00 64.66  ? 87  LEU A CA  1 
ATOM   4643 C  C   . LEU B 1 87  ? 136.659 132.477 118.724 1.00 64.66  ? 87  LEU A C   1 
ATOM   4644 O  O   . LEU B 1 87  ? 137.104 132.314 119.870 1.00 64.66  ? 87  LEU A O   1 
ATOM   4645 C  CB  . LEU B 1 87  ? 137.324 130.969 116.829 1.00 64.66  ? 87  LEU A CB  1 
ATOM   4646 C  CG  . LEU B 1 87  ? 136.960 129.877 115.823 1.00 64.66  ? 87  LEU A CG  1 
ATOM   4647 C  CD1 . LEU B 1 87  ? 138.110 129.620 114.866 1.00 64.66  ? 87  LEU A CD1 1 
ATOM   4648 C  CD2 . LEU B 1 87  ? 136.559 128.600 116.540 1.00 64.66  ? 87  LEU A CD2 1 
ATOM   4649 N  N   . LEU B 1 88  ? 136.509 133.688 118.184 1.00 62.16  ? 88  LEU A N   1 
ATOM   4650 C  CA  . LEU B 1 88  ? 136.814 134.888 118.954 1.00 62.16  ? 88  LEU A CA  1 
ATOM   4651 C  C   . LEU B 1 88  ? 135.920 134.990 120.181 1.00 62.16  ? 88  LEU A C   1 
ATOM   4652 O  O   . LEU B 1 88  ? 136.381 135.353 121.271 1.00 62.16  ? 88  LEU A O   1 
ATOM   4653 C  CB  . LEU B 1 88  ? 136.657 136.122 118.069 1.00 62.16  ? 88  LEU A CB  1 
ATOM   4654 C  CG  . LEU B 1 88  ? 136.804 137.480 118.748 1.00 62.16  ? 88  LEU A CG  1 
ATOM   4655 C  CD1 . LEU B 1 88  ? 138.211 137.642 119.270 1.00 62.16  ? 88  LEU A CD1 1 
ATOM   4656 C  CD2 . LEU B 1 88  ? 136.456 138.597 117.780 1.00 62.16  ? 88  LEU A CD2 1 
ATOM   4657 N  N   . LEU B 1 89  ? 134.635 134.672 120.020 1.00 58.54  ? 89  LEU A N   1 
ATOM   4658 C  CA  . LEU B 1 89  ? 133.713 134.702 121.147 1.00 58.54  ? 89  LEU A CA  1 
ATOM   4659 C  C   . LEU B 1 89  ? 134.119 133.697 122.216 1.00 58.54  ? 89  LEU A C   1 
ATOM   4660 O  O   . LEU B 1 89  ? 134.065 134.000 123.413 1.00 58.54  ? 89  LEU A O   1 
ATOM   4661 C  CB  . LEU B 1 89  ? 132.295 134.427 120.655 1.00 58.54  ? 89  LEU A CB  1 
ATOM   4662 C  CG  . LEU B 1 89  ? 131.189 134.302 121.696 1.00 58.54  ? 89  LEU A CG  1 
ATOM   4663 C  CD1 . LEU B 1 89  ? 131.153 135.534 122.579 1.00 58.54  ? 89  LEU A CD1 1 
ATOM   4664 C  CD2 . LEU B 1 89  ? 129.862 134.097 120.992 1.00 58.54  ? 89  LEU A CD2 1 
ATOM   4665 N  N   . ILE B 1 90  ? 134.535 132.499 121.803 1.00 55.67  ? 90  ILE A N   1 
ATOM   4666 C  CA  . ILE B 1 90  ? 134.972 131.490 122.765 1.00 55.67  ? 90  ILE A CA  1 
ATOM   4667 C  C   . ILE B 1 90  ? 136.200 131.974 123.524 1.00 55.67  ? 90  ILE A C   1 
ATOM   4668 O  O   . ILE B 1 90  ? 136.299 131.808 124.747 1.00 55.67  ? 90  ILE A O   1 
ATOM   4669 C  CB  . ILE B 1 90  ? 135.233 130.148 122.054 1.00 55.67  ? 90  ILE A CB  1 
ATOM   4670 C  CG1 . ILE B 1 90  ? 133.923 129.555 121.536 1.00 55.67  ? 90  ILE A CG1 1 
ATOM   4671 C  CG2 . ILE B 1 90  ? 135.904 129.166 122.994 1.00 55.67  ? 90  ILE A CG2 1 
ATOM   4672 C  CD1 . ILE B 1 90  ? 134.096 128.269 120.756 1.00 55.67  ? 90  ILE A CD1 1 
ATOM   4673 N  N   . GLY B 1 91  ? 137.154 132.583 122.817 1.00 53.52  ? 91  GLY A N   1 
ATOM   4674 C  CA  . GLY B 1 91  ? 138.336 133.103 123.492 1.00 53.52  ? 91  GLY A CA  1 
ATOM   4675 C  C   . GLY B 1 91  ? 138.001 134.190 124.497 1.00 53.52  ? 91  GLY A C   1 
ATOM   4676 O  O   . GLY B 1 91  ? 138.510 134.198 125.626 1.00 53.52  ? 91  GLY A O   1 
ATOM   4677 N  N   . VAL B 1 92  ? 137.128 135.119 124.105 1.00 50.91  ? 92  VAL A N   1 
ATOM   4678 C  CA  . VAL B 1 92  ? 136.750 136.202 125.009 1.00 50.91  ? 92  VAL A CA  1 
ATOM   4679 C  C   . VAL B 1 92  ? 136.006 135.655 126.220 1.00 50.91  ? 92  VAL A C   1 
ATOM   4680 O  O   . VAL B 1 92  ? 136.176 136.144 127.342 1.00 50.91  ? 92  VAL A O   1 
ATOM   4681 C  CB  . VAL B 1 92  ? 135.920 137.262 124.265 1.00 50.91  ? 92  VAL A CB  1 
ATOM   4682 C  CG1 . VAL B 1 92  ? 135.413 138.304 125.239 1.00 50.91  ? 92  VAL A CG1 1 
ATOM   4683 C  CG2 . VAL B 1 92  ? 136.753 137.918 123.181 1.00 50.91  ? 92  VAL A CG2 1 
ATOM   4684 N  N   . ILE B 1 93  ? 135.172 134.633 126.018 1.00 51.16  ? 93  ILE A N   1 
ATOM   4685 C  CA  . ILE B 1 93  ? 134.445 134.055 127.144 1.00 51.16  ? 93  ILE A CA  1 
ATOM   4686 C  C   . ILE B 1 93  ? 135.400 133.331 128.084 1.00 51.16  ? 93  ILE A C   1 
ATOM   4687 O  O   . ILE B 1 93  ? 135.227 133.367 129.308 1.00 51.16  ? 93  ILE A O   1 
ATOM   4688 C  CB  . ILE B 1 93  ? 133.320 133.133 126.645 1.00 51.16  ? 93  ILE A CB  1 
ATOM   4689 C  CG1 . ILE B 1 93  ? 132.241 133.954 125.940 1.00 51.16  ? 93  ILE A CG1 1 
ATOM   4690 C  CG2 . ILE B 1 93  ? 132.702 132.381 127.806 1.00 51.16  ? 93  ILE A CG2 1 
ATOM   4691 C  CD1 . ILE B 1 93  ? 131.748 135.135 126.740 1.00 51.16  ? 93  ILE A CD1 1 
ATOM   4692 N  N   . CYS B 1 94  ? 136.420 132.664 127.538 1.00 50.47  ? 94  CYS A N   1 
ATOM   4693 C  CA  . CYS B 1 94  ? 137.447 132.071 128.390 1.00 50.47  ? 94  CYS A CA  1 
ATOM   4694 C  C   . CYS B 1 94  ? 138.117 133.137 129.246 1.00 50.47  ? 94  CYS A C   1 
ATOM   4695 O  O   . CYS B 1 94  ? 138.293 132.966 130.461 1.00 50.47  ? 94  CYS A O   1 
ATOM   4696 C  CB  . CYS B 1 94  ? 138.490 131.346 127.538 1.00 50.47  ? 94  CYS A CB  1 
ATOM   4697 S  SG  . CYS B 1 94  ? 137.946 129.798 126.798 1.00 50.47  ? 94  CYS A SG  1 
ATOM   4698 N  N   . LEU B 1 95  ? 138.487 134.256 128.620 1.00 50.40  ? 95  LEU A N   1 
ATOM   4699 C  CA  . LEU B 1 95  ? 139.126 135.343 129.357 1.00 50.40  ? 95  LEU A CA  1 
ATOM   4700 C  C   . LEU B 1 95  ? 138.213 135.876 130.456 1.00 50.40  ? 95  LEU A C   1 
ATOM   4701 O  O   . LEU B 1 95  ? 138.648 136.091 131.594 1.00 50.40  ? 95  LEU A O   1 
ATOM   4702 C  CB  . LEU B 1 95  ? 139.511 136.462 128.393 1.00 50.40  ? 95  LEU A CB  1 
ATOM   4703 C  CG  . LEU B 1 95  ? 140.113 137.719 129.014 1.00 50.40  ? 95  LEU A CG  1 
ATOM   4704 C  CD1 . LEU B 1 95  ? 141.359 137.376 129.809 1.00 50.40  ? 95  LEU A CD1 1 
ATOM   4705 C  CD2 . LEU B 1 95  ? 140.413 138.744 127.937 1.00 50.40  ? 95  LEU A CD2 1 
ATOM   4706 N  N   . ALA B 1 96  ? 136.937 136.091 130.129 1.00 49.19  ? 96  ALA A N   1 
ATOM   4707 C  CA  . ALA B 1 96  ? 135.995 136.633 131.102 1.00 49.19  ? 96  ALA A CA  1 
ATOM   4708 C  C   . ALA B 1 96  ? 135.773 135.669 132.259 1.00 49.19  ? 96  ALA A C   1 
ATOM   4709 O  O   . ALA B 1 96  ? 135.692 136.093 133.417 1.00 49.19  ? 96  ALA A O   1 
ATOM   4710 C  CB  . ALA B 1 96  ? 134.670 136.966 130.420 1.00 49.19  ? 96  ALA A CB  1 
ATOM   4711 N  N   . THR B 1 97  ? 135.663 134.373 131.967 1.00 49.60  ? 97  THR A N   1 
ATOM   4712 C  CA  . THR B 1 97  ? 135.480 133.383 133.022 1.00 49.60  ? 97  THR A CA  1 
ATOM   4713 C  C   . THR B 1 97  ? 136.681 133.354 133.956 1.00 49.60  ? 97  THR A C   1 
ATOM   4714 O  O   . THR B 1 97  ? 136.530 133.324 135.184 1.00 49.60  ? 97  THR A O   1 
ATOM   4715 C  CB  . THR B 1 97  ? 135.248 132.003 132.408 1.00 49.60  ? 97  THR A CB  1 
ATOM   4716 O  OG1 . THR B 1 97  ? 134.350 132.118 131.298 1.00 49.60  ? 97  THR A OG1 1 
ATOM   4717 C  CG2 . THR B 1 97  ? 134.661 131.055 133.437 1.00 49.60  ? 97  THR A CG2 1 
ATOM   4718 N  N   . SER B 1 98  ? 137.889 133.369 133.388 1.00 49.88  ? 98  SER A N   1 
ATOM   4719 C  CA  . SER B 1 98  ? 139.083 133.362 134.225 1.00 49.88  ? 98  SER A CA  1 
ATOM   4720 C  C   . SER B 1 98  ? 139.165 134.621 135.077 1.00 49.88  ? 98  SER A C   1 
ATOM   4721 O  O   . SER B 1 98  ? 139.560 134.562 136.246 1.00 49.88  ? 98  SER A O   1 
ATOM   4722 C  CB  . SER B 1 98  ? 140.333 133.215 133.363 1.00 49.88  ? 98  SER A CB  1 
ATOM   4723 O  OG  . SER B 1 98  ? 141.501 133.383 134.145 1.00 49.88  ? 98  SER A OG  1 
ATOM   4724 N  N   . ILE B 1 99  ? 138.802 135.771 134.507 1.00 52.63  ? 99  ILE A N   1 
ATOM   4725 C  CA  . ILE B 1 99  ? 138.817 137.016 135.272 1.00 52.63  ? 99  ILE A CA  1 
ATOM   4726 C  C   . ILE B 1 99  ? 137.813 136.949 136.416 1.00 52.63  ? 99  ILE A C   1 
ATOM   4727 O  O   . ILE B 1 99  ? 138.112 137.327 137.554 1.00 52.63  ? 99  ILE A O   1 
ATOM   4728 C  CB  . ILE B 1 99  ? 138.536 138.216 134.349 1.00 52.63  ? 99  ILE A CB  1 
ATOM   4729 C  CG1 . ILE B 1 99  ? 139.766 138.548 133.509 1.00 52.63  ? 99  ILE A CG1 1 
ATOM   4730 C  CG2 . ILE B 1 99  ? 138.113 139.428 135.156 1.00 52.63  ? 99  ILE A CG2 1 
ATOM   4731 C  CD1 . ILE B 1 99  ? 139.510 139.606 132.466 1.00 52.63  ? 99  ILE A CD1 1 
ATOM   4732 N  N   . GLU B 1 100 ? 136.608 136.455 136.131 1.00 58.52  ? 100 GLU A N   1 
ATOM   4733 C  CA  . GLU B 1 100 ? 135.526 136.520 137.107 1.00 58.52  ? 100 GLU A CA  1 
ATOM   4734 C  C   . GLU B 1 100 ? 135.740 135.537 138.251 1.00 58.52  ? 100 GLU A C   1 
ATOM   4735 O  O   . GLU B 1 100 ? 135.559 135.888 139.422 1.00 58.52  ? 100 GLU A O   1 
ATOM   4736 C  CB  . GLU B 1 100 ? 134.187 136.262 136.415 1.00 58.52  ? 100 GLU A CB  1 
ATOM   4737 C  CG  . GLU B 1 100 ? 132.974 136.416 137.317 1.00 58.52  ? 100 GLU A CG  1 
ATOM   4738 C  CD  . GLU B 1 100 ? 132.523 135.102 137.923 1.00 58.52  ? 100 GLU A CD  1 
ATOM   4739 O  OE1 . GLU B 1 100 ? 133.158 134.066 137.637 1.00 58.52  ? 100 GLU A OE1 1 
ATOM   4740 O  OE2 . GLU B 1 100 ? 131.532 135.105 138.683 1.00 58.52  ? 100 GLU A OE2 1 
ATOM   4741 N  N   . LYS B 1 101 ? 136.125 134.297 137.936 1.00 57.47  ? 101 LYS A N   1 
ATOM   4742 C  CA  . LYS B 1 101 ? 136.157 133.267 138.970 1.00 57.47  ? 101 LYS A CA  1 
ATOM   4743 C  C   . LYS B 1 101 ? 137.256 133.495 140.001 1.00 57.47  ? 101 LYS A C   1 
ATOM   4744 O  O   . LYS B 1 101 ? 137.224 132.867 141.064 1.00 57.47  ? 101 LYS A O   1 
ATOM   4745 C  CB  . LYS B 1 101 ? 136.315 131.881 138.343 1.00 57.47  ? 101 LYS A CB  1 
ATOM   4746 C  CG  . LYS B 1 101 ? 137.722 131.562 137.887 1.00 57.47  ? 101 LYS A CG  1 
ATOM   4747 C  CD  . LYS B 1 101 ? 137.888 130.077 137.618 1.00 57.47  ? 101 LYS A CD  1 
ATOM   4748 C  CE  . LYS B 1 101 ? 138.053 129.299 138.912 1.00 57.47  ? 101 LYS A CE  1 
ATOM   4749 N  NZ  . LYS B 1 101 ? 138.475 127.893 138.667 1.00 57.47  ? 101 LYS A NZ  1 
ATOM   4750 N  N   . TRP B 1 102 ? 138.222 134.368 139.721 1.00 59.28  ? 102 TRP A N   1 
ATOM   4751 C  CA  . TRP B 1 102 ? 139.288 134.674 140.667 1.00 59.28  ? 102 TRP A CA  1 
ATOM   4752 C  C   . TRP B 1 102 ? 139.164 136.070 141.264 1.00 59.28  ? 102 TRP A C   1 
ATOM   4753 O  O   . TRP B 1 102 ? 140.081 136.518 141.960 1.00 59.28  ? 102 TRP A O   1 
ATOM   4754 C  CB  . TRP B 1 102 ? 140.654 134.504 140.000 1.00 59.28  ? 102 TRP A CB  1 
ATOM   4755 C  CG  . TRP B 1 102 ? 140.882 133.118 139.502 1.00 59.28  ? 102 TRP A CG  1 
ATOM   4756 C  CD1 . TRP B 1 102 ? 140.883 132.706 138.205 1.00 59.28  ? 102 TRP A CD1 1 
ATOM   4757 C  CD2 . TRP B 1 102 ? 141.129 131.952 140.294 1.00 59.28  ? 102 TRP A CD2 1 
ATOM   4758 N  NE1 . TRP B 1 102 ? 141.118 131.356 138.138 1.00 59.28  ? 102 TRP A NE1 1 
ATOM   4759 C  CE2 . TRP B 1 102 ? 141.275 130.869 139.408 1.00 59.28  ? 102 TRP A CE2 1 
ATOM   4760 C  CE3 . TRP B 1 102 ? 141.246 131.720 141.667 1.00 59.28  ? 102 TRP A CE3 1 
ATOM   4761 C  CZ2 . TRP B 1 102 ? 141.530 129.575 139.849 1.00 59.28  ? 102 TRP A CZ2 1 
ATOM   4762 C  CZ3 . TRP B 1 102 ? 141.498 130.434 142.101 1.00 59.28  ? 102 TRP A CZ3 1 
ATOM   4763 C  CH2 . TRP B 1 102 ? 141.638 129.378 141.196 1.00 59.28  ? 102 TRP A CH2 1 
ATOM   4764 N  N   . ASN B 1 103 ? 138.052 136.763 141.011 1.00 64.57  ? 103 ASN A N   1 
ATOM   4765 C  CA  . ASN B 1 103 ? 137.772 138.071 141.604 1.00 64.57  ? 103 ASN A CA  1 
ATOM   4766 C  C   . ASN B 1 103 ? 138.879 139.080 141.299 1.00 64.57  ? 103 ASN A C   1 
ATOM   4767 O  O   . ASN B 1 103 ? 139.284 139.871 142.152 1.00 64.57  ? 103 ASN A O   1 
ATOM   4768 C  CB  . ASN B 1 103 ? 137.543 137.949 143.112 1.00 64.57  ? 103 ASN A CB  1 
ATOM   4769 C  CG  . ASN B 1 103 ? 136.498 136.910 143.457 1.00 64.57  ? 103 ASN A CG  1 
ATOM   4770 O  OD1 . ASN B 1 103 ? 135.726 136.482 142.601 1.00 64.57  ? 103 ASN A OD1 1 
ATOM   4771 N  ND2 . ASN B 1 103 ? 136.467 136.497 144.719 1.00 64.57  ? 103 ASN A ND2 1 
ATOM   4772 N  N   . LEU B 1 104 ? 139.378 139.041 140.063 1.00 63.75  ? 104 LEU A N   1 
ATOM   4773 C  CA  . LEU B 1 104 ? 140.321 140.059 139.615 1.00 63.75  ? 104 LEU A CA  1 
ATOM   4774 C  C   . LEU B 1 104 ? 139.619 141.372 139.291 1.00 63.75  ? 104 LEU A C   1 
ATOM   4775 O  O   . LEU B 1 104 ? 140.201 142.449 139.478 1.00 63.75  ? 104 LEU A O   1 
ATOM   4776 C  CB  . LEU B 1 104 ? 141.096 139.560 138.396 1.00 63.75  ? 104 LEU A CB  1 
ATOM   4777 C  CG  . LEU B 1 104 ? 142.091 140.535 137.768 1.00 63.75  ? 104 LEU A CG  1 
ATOM   4778 C  CD1 . LEU B 1 104 ? 143.208 140.851 138.744 1.00 63.75  ? 104 LEU A CD1 1 
ATOM   4779 C  CD2 . LEU B 1 104 ? 142.651 139.973 136.475 1.00 63.75  ? 104 LEU A CD2 1 
ATOM   4780 N  N   . HIS B 1 105 ? 138.373 141.300 138.816 1.00 64.63  ? 105 HIS A N   1 
ATOM   4781 C  CA  . HIS B 1 105 ? 137.637 142.511 138.475 1.00 64.63  ? 105 HIS A CA  1 
ATOM   4782 C  C   . HIS B 1 105 ? 137.418 143.385 139.701 1.00 64.63  ? 105 HIS A C   1 
ATOM   4783 O  O   . HIS B 1 105 ? 137.451 144.617 139.606 1.00 64.63  ? 105 HIS A O   1 
ATOM   4784 C  CB  . HIS B 1 105 ? 136.301 142.152 137.828 1.00 64.63  ? 105 HIS A CB  1 
ATOM   4785 C  CG  . HIS B 1 105 ? 135.578 141.034 138.512 1.00 64.63  ? 105 HIS A CG  1 
ATOM   4786 N  ND1 . HIS B 1 105 ? 134.892 141.203 139.695 1.00 64.63  ? 105 HIS A ND1 1 
ATOM   4787 C  CD2 . HIS B 1 105 ? 135.427 139.733 138.173 1.00 64.63  ? 105 HIS A CD2 1 
ATOM   4788 C  CE1 . HIS B 1 105 ? 134.353 140.053 140.058 1.00 64.63  ? 105 HIS A CE1 1 
ATOM   4789 N  NE2 . HIS B 1 105 ? 134.663 139.145 139.152 1.00 64.63  ? 105 HIS A NE2 1 
ATOM   4790 N  N   . LYS B 1 106 ? 137.186 142.768 140.861 1.00 66.55  ? 106 LYS A N   1 
ATOM   4791 C  CA  . LYS B 1 106 ? 137.060 143.545 142.088 1.00 66.55  ? 106 LYS A CA  1 
ATOM   4792 C  C   . LYS B 1 106 ? 138.344 144.306 142.385 1.00 66.55  ? 106 LYS A C   1 
ATOM   4793 O  O   . LYS B 1 106 ? 138.305 145.488 142.745 1.00 66.55  ? 106 LYS A O   1 
ATOM   4794 C  CB  . LYS B 1 106 ? 136.695 142.632 143.257 1.00 66.55  ? 106 LYS A CB  1 
ATOM   4795 C  CG  . LYS B 1 106 ? 135.357 141.937 143.103 1.00 66.55  ? 106 LYS A CG  1 
ATOM   4796 C  CD  . LYS B 1 106 ? 135.224 140.776 144.071 1.00 66.55  ? 106 LYS A CD  1 
ATOM   4797 C  CE  . LYS B 1 106 ? 133.788 140.613 144.540 1.00 66.55  ? 106 LYS A CE  1 
ATOM   4798 N  NZ  . LYS B 1 106 ? 133.717 140.236 145.978 1.00 66.55  ? 106 LYS A NZ  1 
ATOM   4799 N  N   . ARG B 1 107 ? 139.495 143.647 142.230 1.00 67.22  ? 107 ARG A N   1 
ATOM   4800 C  CA  . ARG B 1 107 ? 140.763 144.325 142.470 1.00 67.22  ? 107 ARG A CA  1 
ATOM   4801 C  C   . ARG B 1 107 ? 140.960 145.478 141.498 1.00 67.22  ? 107 ARG A C   1 
ATOM   4802 O  O   . ARG B 1 107 ? 141.391 146.566 141.896 1.00 67.22  ? 107 ARG A O   1 
ATOM   4803 C  CB  . ARG B 1 107 ? 141.921 143.336 142.369 1.00 67.22  ? 107 ARG A CB  1 
ATOM   4804 C  CG  . ARG B 1 107 ? 143.242 143.896 142.864 1.00 67.22  ? 107 ARG A CG  1 
ATOM   4805 C  CD  . ARG B 1 107 ? 144.281 142.804 143.017 1.00 67.22  ? 107 ARG A CD  1 
ATOM   4806 N  NE  . ARG B 1 107 ? 143.724 141.613 143.644 1.00 67.22  ? 107 ARG A NE  1 
ATOM   4807 C  CZ  . ARG B 1 107 ? 143.839 141.323 144.933 1.00 67.22  ? 107 ARG A CZ  1 
ATOM   4808 N  NH1 . ARG B 1 107 ? 144.493 142.119 145.764 1.00 67.22  ? 107 ARG A NH1 1 
ATOM   4809 N  NH2 . ARG B 1 107 ? 143.285 140.208 145.399 1.00 67.22  ? 107 ARG A NH2 1 
ATOM   4810 N  N   . ILE B 1 108 ? 140.634 145.266 140.221 1.00 64.24  ? 108 ILE A N   1 
ATOM   4811 C  CA  . ILE B 1 108 ? 140.791 146.326 139.227 1.00 64.24  ? 108 ILE A CA  1 
ATOM   4812 C  C   . ILE B 1 108 ? 139.900 147.516 139.568 1.00 64.24  ? 108 ILE A C   1 
ATOM   4813 O  O   . ILE B 1 108 ? 140.336 148.676 139.536 1.00 64.24  ? 108 ILE A O   1 
ATOM   4814 C  CB  . ILE B 1 108 ? 140.490 145.789 137.817 1.00 64.24  ? 108 ILE A CB  1 
ATOM   4815 C  CG1 . ILE B 1 108 ? 141.431 144.638 137.467 1.00 64.24  ? 108 ILE A CG1 1 
ATOM   4816 C  CG2 . ILE B 1 108 ? 140.607 146.895 136.790 1.00 64.24  ? 108 ILE A CG2 1 
ATOM   4817 C  CD1 . ILE B 1 108 ? 141.164 144.034 136.109 1.00 64.24  ? 108 ILE A CD1 1 
ATOM   4818 N  N   . ALA B 1 109 ? 138.635 147.244 139.898 1.00 63.22  ? 109 ALA A N   1 
ATOM   4819 C  CA  . ALA B 1 109 ? 137.694 148.318 140.193 1.00 63.22  ? 109 ALA A CA  1 
ATOM   4820 C  C   . ALA B 1 109 ? 138.121 149.101 141.427 1.00 63.22  ? 109 ALA A C   1 
ATOM   4821 O  O   . ALA B 1 109 ? 138.100 150.337 141.428 1.00 63.22  ? 109 ALA A O   1 
ATOM   4822 C  CB  . ALA B 1 109 ? 136.289 147.745 140.377 1.00 63.22  ? 109 ALA A CB  1 
ATOM   4823 N  N   . LEU B 1 110 ? 138.517 148.397 142.490 1.00 67.25  ? 110 LEU A N   1 
ATOM   4824 C  CA  . LEU B 1 110 ? 138.954 149.088 143.698 1.00 67.25  ? 110 LEU A CA  1 
ATOM   4825 C  C   . LEU B 1 110 ? 140.220 149.895 143.446 1.00 67.25  ? 110 LEU A C   1 
ATOM   4826 O  O   . LEU B 1 110 ? 140.362 151.011 143.959 1.00 67.25  ? 110 LEU A O   1 
ATOM   4827 C  CB  . LEU B 1 110 ? 139.166 148.092 144.838 1.00 67.25  ? 110 LEU A CB  1 
ATOM   4828 C  CG  . LEU B 1 110 ? 137.954 147.761 145.714 1.00 67.25  ? 110 LEU A CG  1 
ATOM   4829 C  CD1 . LEU B 1 110 ? 137.496 149.006 146.456 1.00 67.25  ? 110 LEU A CD1 1 
ATOM   4830 C  CD2 . LEU B 1 110 ? 136.807 147.170 144.919 1.00 67.25  ? 110 LEU A CD2 1 
ATOM   4831 N  N   . LYS B 1 111 ? 141.150 149.354 142.655 1.00 71.20  ? 111 LYS A N   1 
ATOM   4832 C  CA  . LYS B 1 111 ? 142.368 150.093 142.351 1.00 71.20  ? 111 LYS A CA  1 
ATOM   4833 C  C   . LYS B 1 111 ? 142.058 151.379 141.598 1.00 71.20  ? 111 LYS A C   1 
ATOM   4834 O  O   . LYS B 1 111 ? 142.588 152.443 141.935 1.00 71.20  ? 111 LYS A O   1 
ATOM   4835 C  CB  . LYS B 1 111 ? 143.330 149.219 141.549 1.00 71.20  ? 111 LYS A CB  1 
ATOM   4836 C  CG  . LYS B 1 111 ? 144.645 149.899 141.214 1.00 71.20  ? 111 LYS A CG  1 
ATOM   4837 C  CD  . LYS B 1 111 ? 145.335 150.422 142.461 1.00 71.20  ? 111 LYS A CD  1 
ATOM   4838 C  CE  . LYS B 1 111 ? 145.819 149.284 143.338 1.00 71.20  ? 111 LYS A CE  1 
ATOM   4839 N  NZ  . LYS B 1 111 ? 146.522 149.778 144.551 1.00 71.20  ? 111 LYS A NZ  1 
ATOM   4840 N  N   . MET B 1 112 ? 141.192 151.307 140.583 1.00 68.77  ? 112 MET A N   1 
ATOM   4841 C  CA  . MET B 1 112 ? 140.845 152.522 139.849 1.00 68.77  ? 112 MET A CA  1 
ATOM   4842 C  C   . MET B 1 112 ? 140.120 153.524 140.739 1.00 68.77  ? 112 MET A C   1 
ATOM   4843 O  O   . MET B 1 112 ? 140.410 154.726 140.693 1.00 68.77  ? 112 MET A O   1 
ATOM   4844 C  CB  . MET B 1 112 ? 140.005 152.191 138.616 1.00 68.77  ? 112 MET A CB  1 
ATOM   4845 C  CG  . MET B 1 112 ? 140.756 151.426 137.542 1.00 68.77  ? 112 MET A CG  1 
ATOM   4846 S  SD  . MET B 1 112 ? 139.727 151.054 136.111 1.00 68.77  ? 112 MET A SD  1 
ATOM   4847 C  CE  . MET B 1 112 ? 140.866 150.094 135.120 1.00 68.77  ? 112 MET A CE  1 
ATOM   4848 N  N   . VAL B 1 113 ? 139.182 153.050 141.564 1.00 70.80  ? 113 VAL A N   1 
ATOM   4849 C  CA  . VAL B 1 113 ? 138.438 153.957 142.435 1.00 70.80  ? 113 VAL A CA  1 
ATOM   4850 C  C   . VAL B 1 113 ? 139.380 154.663 143.401 1.00 70.80  ? 113 VAL A C   1 
ATOM   4851 O  O   . VAL B 1 113 ? 139.274 155.877 143.619 1.00 70.80  ? 113 VAL A O   1 
ATOM   4852 C  CB  . VAL B 1 113 ? 137.328 153.194 143.180 1.00 70.80  ? 113 VAL A CB  1 
ATOM   4853 C  CG1 . VAL B 1 113 ? 136.783 154.029 144.323 1.00 70.80  ? 113 VAL A CG1 1 
ATOM   4854 C  CG2 . VAL B 1 113 ? 136.213 152.820 142.221 1.00 70.80  ? 113 VAL A CG2 1 
ATOM   4855 N  N   . MET B 1 114 ? 140.319 153.921 143.991 1.00 77.82  ? 114 MET A N   1 
ATOM   4856 C  CA  . MET B 1 114 ? 141.273 154.533 144.909 1.00 77.82  ? 114 MET A CA  1 
ATOM   4857 C  C   . MET B 1 114 ? 142.202 155.499 144.183 1.00 77.82  ? 114 MET A C   1 
ATOM   4858 O  O   . MET B 1 114 ? 142.540 156.562 144.715 1.00 77.82  ? 114 MET A O   1 
ATOM   4859 C  CB  . MET B 1 114 ? 142.079 153.449 145.624 1.00 77.82  ? 114 MET A CB  1 
ATOM   4860 C  CG  . MET B 1 114 ? 143.153 153.986 146.551 1.00 77.82  ? 114 MET A CG  1 
ATOM   4861 S  SD  . MET B 1 114 ? 144.064 152.681 147.395 1.00 77.82  ? 114 MET A SD  1 
ATOM   4862 C  CE  . MET B 1 114 ? 145.400 152.405 146.236 1.00 77.82  ? 114 MET A CE  1 
ATOM   4863 N  N   . MET B 1 115 ? 142.620 155.151 142.964 1.00 78.92  ? 115 MET A N   1 
ATOM   4864 C  CA  . MET B 1 115 ? 143.621 155.950 142.269 1.00 78.92  ? 115 MET A CA  1 
ATOM   4865 C  C   . MET B 1 115 ? 143.046 157.250 141.721 1.00 78.92  ? 115 MET A C   1 
ATOM   4866 O  O   . MET B 1 115 ? 143.753 158.264 141.683 1.00 78.92  ? 115 MET A O   1 
ATOM   4867 C  CB  . MET B 1 115 ? 144.246 155.127 141.143 1.00 78.92  ? 115 MET A CB  1 
ATOM   4868 C  CG  . MET B 1 115 ? 145.331 155.846 140.362 1.00 78.92  ? 115 MET A CG  1 
ATOM   4869 S  SD  . MET B 1 115 ? 145.715 155.023 138.805 1.00 78.92  ? 115 MET A SD  1 
ATOM   4870 C  CE  . MET B 1 115 ? 145.719 153.309 139.321 1.00 78.92  ? 115 MET A CE  1 
ATOM   4871 N  N   . VAL B 1 116 ? 141.780 157.249 141.291 1.00 79.02  ? 116 VAL A N   1 
ATOM   4872 C  CA  . VAL B 1 116 ? 141.236 158.425 140.610 1.00 79.02  ? 116 VAL A CA  1 
ATOM   4873 C  C   . VAL B 1 116 ? 141.224 159.636 141.536 1.00 79.02  ? 116 VAL A C   1 
ATOM   4874 O  O   . VAL B 1 116 ? 141.660 160.729 141.153 1.00 79.02  ? 116 VAL A O   1 
ATOM   4875 C  CB  . VAL B 1 116 ? 139.835 158.126 140.048 1.00 79.02  ? 116 VAL A CB  1 
ATOM   4876 C  CG1 . VAL B 1 116 ? 139.143 159.416 139.660 1.00 79.02  ? 116 VAL A CG1 1 
ATOM   4877 C  CG2 . VAL B 1 116 ? 139.941 157.219 138.838 1.00 79.02  ? 116 VAL A CG2 1 
ATOM   4878 N  N   . GLY B 1 117 ? 140.743 159.470 142.756 1.00 83.19  ? 117 GLY A N   1 
ATOM   4879 C  CA  . GLY B 1 117 ? 140.752 160.554 143.716 1.00 83.19  ? 117 GLY A CA  1 
ATOM   4880 C  C   . GLY B 1 117 ? 139.667 160.373 144.758 1.00 83.19  ? 117 GLY A C   1 
ATOM   4881 O  O   . GLY B 1 117 ? 139.016 159.335 144.834 1.00 83.19  ? 117 GLY A O   1 
ATOM   4882 N  N   . VAL B 1 118 ? 139.492 161.418 145.563 1.00 89.92  ? 118 VAL A N   1 
ATOM   4883 C  CA  . VAL B 1 118 ? 138.517 161.415 146.648 1.00 89.92  ? 118 VAL A CA  1 
ATOM   4884 C  C   . VAL B 1 118 ? 137.428 162.461 146.473 1.00 89.92  ? 118 VAL A C   1 
ATOM   4885 O  O   . VAL B 1 118 ? 136.449 162.443 147.234 1.00 89.92  ? 118 VAL A O   1 
ATOM   4886 C  CB  . VAL B 1 118 ? 139.201 161.598 148.020 1.00 89.92  ? 118 VAL A CB  1 
ATOM   4887 C  CG1 . VAL B 1 118 ? 140.142 160.438 148.302 1.00 89.92  ? 118 VAL A CG1 1 
ATOM   4888 C  CG2 . VAL B 1 118 ? 139.946 162.922 148.066 1.00 89.92  ? 118 VAL A CG2 1 
ATOM   4889 N  N   . ASN B 1 119 ? 137.563 163.374 145.518 1.00 85.13  ? 119 ASN A N   1 
ATOM   4890 C  CA  . ASN B 1 119 ? 136.506 164.338 145.248 1.00 85.13  ? 119 ASN A CA  1 
ATOM   4891 C  C   . ASN B 1 119 ? 135.250 163.598 144.796 1.00 85.13  ? 119 ASN A C   1 
ATOM   4892 O  O   . ASN B 1 119 ? 135.337 162.722 143.924 1.00 85.13  ? 119 ASN A O   1 
ATOM   4893 C  CB  . ASN B 1 119 ? 136.962 165.327 144.175 1.00 85.13  ? 119 ASN A CB  1 
ATOM   4894 C  CG  . ASN B 1 119 ? 136.279 166.677 144.287 1.00 85.13  ? 119 ASN A CG  1 
ATOM   4895 O  OD1 . ASN B 1 119 ? 135.078 166.763 144.534 1.00 85.13  ? 119 ASN A OD1 1 
ATOM   4896 N  ND2 . ASN B 1 119 ? 137.048 167.743 144.102 1.00 85.13  ? 119 ASN A ND2 1 
ATOM   4897 N  N   . PRO B 1 120 ? 134.079 163.900 145.367 1.00 78.94  ? 120 PRO A N   1 
ATOM   4898 C  CA  . PRO B 1 120 ? 132.867 163.145 144.998 1.00 78.94  ? 120 PRO A CA  1 
ATOM   4899 C  C   . PRO B 1 120 ? 132.576 163.128 143.506 1.00 78.94  ? 120 PRO A C   1 
ATOM   4900 O  O   . PRO B 1 120 ? 132.168 162.087 142.976 1.00 78.94  ? 120 PRO A O   1 
ATOM   4901 C  CB  . PRO B 1 120 ? 131.766 163.867 145.784 1.00 78.94  ? 120 PRO A CB  1 
ATOM   4902 C  CG  . PRO B 1 120 ? 132.466 164.405 146.983 1.00 78.94  ? 120 PRO A CG  1 
ATOM   4903 C  CD  . PRO B 1 120 ? 133.858 164.766 146.538 1.00 78.94  ? 120 PRO A CD  1 
ATOM   4904 N  N   . ALA B 1 121 ? 132.783 164.245 142.807 1.00 72.51  ? 121 ALA A N   1 
ATOM   4905 C  CA  . ALA B 1 121 ? 132.655 164.231 141.354 1.00 72.51  ? 121 ALA A CA  1 
ATOM   4906 C  C   . ALA B 1 121 ? 133.701 163.318 140.730 1.00 72.51  ? 121 ALA A C   1 
ATOM   4907 O  O   . ALA B 1 121 ? 133.393 162.497 139.856 1.00 72.51  ? 121 ALA A O   1 
ATOM   4908 C  CB  . ALA B 1 121 ? 132.775 165.651 140.802 1.00 72.51  ? 121 ALA A CB  1 
ATOM   4909 N  N   . TRP B 1 122 ? 134.950 163.435 141.185 1.00 74.57  ? 122 TRP A N   1 
ATOM   4910 C  CA  . TRP B 1 122 ? 135.993 162.544 140.698 1.00 74.57  ? 122 TRP A CA  1 
ATOM   4911 C  C   . TRP B 1 122 ? 135.736 161.107 141.126 1.00 74.57  ? 122 TRP A C   1 
ATOM   4912 O  O   . TRP B 1 122 ? 136.087 160.176 140.396 1.00 74.57  ? 122 TRP A O   1 
ATOM   4913 C  CB  . TRP B 1 122 ? 137.361 163.016 141.188 1.00 74.57  ? 122 TRP A CB  1 
ATOM   4914 C  CG  . TRP B 1 122 ? 137.875 164.217 140.450 1.00 74.57  ? 122 TRP A CG  1 
ATOM   4915 C  CD1 . TRP B 1 122 ? 137.993 165.486 140.933 1.00 74.57  ? 122 TRP A CD1 1 
ATOM   4916 C  CD2 . TRP B 1 122 ? 138.332 164.260 139.094 1.00 74.57  ? 122 TRP A CD2 1 
ATOM   4917 N  NE1 . TRP B 1 122 ? 138.499 166.317 139.964 1.00 74.57  ? 122 TRP A NE1 1 
ATOM   4918 C  CE2 . TRP B 1 122 ? 138.716 165.588 138.825 1.00 74.57  ? 122 TRP A CE2 1 
ATOM   4919 C  CE3 . TRP B 1 122 ? 138.457 163.304 138.081 1.00 74.57  ? 122 TRP A CE3 1 
ATOM   4920 C  CZ2 . TRP B 1 122 ? 139.214 165.984 137.587 1.00 74.57  ? 122 TRP A CZ2 1 
ATOM   4921 C  CZ3 . TRP B 1 122 ? 138.952 163.699 136.854 1.00 74.57  ? 122 TRP A CZ3 1 
ATOM   4922 C  CH2 . TRP B 1 122 ? 139.324 165.027 136.617 1.00 74.57  ? 122 TRP A CH2 1 
ATOM   4923 N  N   . LEU B 1 123 ? 135.118 160.903 142.291 1.00 68.17  ? 123 LEU A N   1 
ATOM   4924 C  CA  . LEU B 1 123 ? 134.771 159.549 142.712 1.00 68.17  ? 123 LEU A CA  1 
ATOM   4925 C  C   . LEU B 1 123 ? 133.736 158.926 141.781 1.00 68.17  ? 123 LEU A C   1 
ATOM   4926 O  O   . LEU B 1 123 ? 133.861 157.756 141.398 1.00 68.17  ? 123 LEU A O   1 
ATOM   4927 C  CB  . LEU B 1 123 ? 134.261 159.564 144.151 1.00 68.17  ? 123 LEU A CB  1 
ATOM   4928 C  CG  . LEU B 1 123 ? 134.102 158.202 144.821 1.00 68.17  ? 123 LEU A CG  1 
ATOM   4929 C  CD1 . LEU B 1 123 ? 135.436 157.482 144.867 1.00 68.17  ? 123 LEU A CD1 1 
ATOM   4930 C  CD2 . LEU B 1 123 ? 133.532 158.362 146.218 1.00 68.17  ? 123 LEU A CD2 1 
ATOM   4931 N  N   . THR B 1 124 ? 132.708 159.692 141.403 1.00 64.95  ? 124 THR A N   1 
ATOM   4932 C  CA  . THR B 1 124 ? 131.727 159.180 140.451 1.00 64.95  ? 124 THR A CA  1 
ATOM   4933 C  C   . THR B 1 124 ? 132.365 158.925 139.092 1.00 64.95  ? 124 THR A C   1 
ATOM   4934 O  O   . THR B 1 124 ? 132.042 157.936 138.423 1.00 64.95  ? 124 THR A O   1 
ATOM   4935 C  CB  . THR B 1 124 ? 130.551 160.146 140.314 1.00 64.95  ? 124 THR A CB  1 
ATOM   4936 O  OG1 . THR B 1 124 ? 131.021 161.413 139.838 1.00 64.95  ? 124 THR A OG1 1 
ATOM   4937 C  CG2 . THR B 1 124 ? 129.852 160.332 141.650 1.00 64.95  ? 124 THR A CG2 1 
ATOM   4938 N  N   . LEU B 1 125 ? 133.272 159.808 138.664 1.00 60.05  ? 125 LEU A N   1 
ATOM   4939 C  CA  . LEU B 1 125 ? 133.967 159.581 137.400 1.00 60.05  ? 125 LEU A CA  1 
ATOM   4940 C  C   . LEU B 1 125 ? 134.796 158.305 137.450 1.00 60.05  ? 125 LEU A C   1 
ATOM   4941 O  O   . LEU B 1 125 ? 134.835 157.544 136.477 1.00 60.05  ? 125 LEU A O   1 
ATOM   4942 C  CB  . LEU B 1 125 ? 134.849 160.779 137.054 1.00 60.05  ? 125 LEU A CB  1 
ATOM   4943 C  CG  . LEU B 1 125 ? 135.538 160.731 135.688 1.00 60.05  ? 125 LEU A CG  1 
ATOM   4944 C  CD1 . LEU B 1 125 ? 134.592 160.224 134.610 1.00 60.05  ? 125 LEU A CD1 1 
ATOM   4945 C  CD2 . LEU B 1 125 ? 136.086 162.097 135.317 1.00 60.05  ? 125 LEU A CD2 1 
ATOM   4946 N  N   . GLY B 1 126 ? 135.470 158.057 138.573 1.00 61.27  ? 126 GLY A N   1 
ATOM   4947 C  CA  . GLY B 1 126 ? 136.232 156.828 138.712 1.00 61.27  ? 126 GLY A CA  1 
ATOM   4948 C  C   . GLY B 1 126 ? 135.351 155.595 138.702 1.00 61.27  ? 126 GLY A C   1 
ATOM   4949 O  O   . GLY B 1 126 ? 135.691 154.584 138.082 1.00 61.27  ? 126 GLY A O   1 
ATOM   4950 N  N   . PHE B 1 127 ? 134.207 155.662 139.386 1.00 58.75  ? 127 PHE A N   1 
ATOM   4951 C  CA  . PHE B 1 127 ? 133.260 154.550 139.354 1.00 58.75  ? 127 PHE A CA  1 
ATOM   4952 C  C   . PHE B 1 127 ? 132.801 154.269 137.929 1.00 58.75  ? 127 PHE A C   1 
ATOM   4953 O  O   . PHE B 1 127 ? 132.782 153.115 137.484 1.00 58.75  ? 127 PHE A O   1 
ATOM   4954 C  CB  . PHE B 1 127 ? 132.057 154.855 140.247 1.00 58.75  ? 127 PHE A CB  1 
ATOM   4955 C  CG  . PHE B 1 127 ? 132.230 154.421 141.671 1.00 58.75  ? 127 PHE A CG  1 
ATOM   4956 C  CD1 . PHE B 1 127 ? 132.391 153.084 141.987 1.00 58.75  ? 127 PHE A CD1 1 
ATOM   4957 C  CD2 . PHE B 1 127 ? 132.213 155.349 142.698 1.00 58.75  ? 127 PHE A CD2 1 
ATOM   4958 C  CE1 . PHE B 1 127 ? 132.546 152.682 143.298 1.00 58.75  ? 127 PHE A CE1 1 
ATOM   4959 C  CE2 . PHE B 1 127 ? 132.365 154.953 144.011 1.00 58.75  ? 127 PHE A CE2 1 
ATOM   4960 C  CZ  . PHE B 1 127 ? 132.531 153.618 144.311 1.00 58.75  ? 127 PHE A CZ  1 
ATOM   4961 N  N   . MET B 1 128 ? 132.439 155.324 137.195 1.00 53.71  ? 128 MET A N   1 
ATOM   4962 C  CA  . MET B 1 128 ? 131.978 155.156 135.821 1.00 53.71  ? 128 MET A CA  1 
ATOM   4963 C  C   . MET B 1 128 ? 133.070 154.573 134.936 1.00 53.71  ? 128 MET A C   1 
ATOM   4964 O  O   . MET B 1 128 ? 132.812 153.663 134.139 1.00 53.71  ? 128 MET A O   1 
ATOM   4965 C  CB  . MET B 1 128 ? 131.502 156.496 135.265 1.00 53.71  ? 128 MET A CB  1 
ATOM   4966 C  CG  . MET B 1 128 ? 130.263 157.032 135.944 1.00 53.71  ? 128 MET A CG  1 
ATOM   4967 S  SD  . MET B 1 128 ? 129.763 158.648 135.336 1.00 53.71  ? 128 MET A SD  1 
ATOM   4968 C  CE  . MET B 1 128 ? 129.179 158.224 133.701 1.00 53.71  ? 128 MET A CE  1 
ATOM   4969 N  N   . SER B 1 129 ? 134.296 155.084 135.061 1.00 54.78  ? 129 SER A N   1 
ATOM   4970 C  CA  . SER B 1 129 ? 135.391 154.597 134.230 1.00 54.78  ? 129 SER A CA  1 
ATOM   4971 C  C   . SER B 1 129 ? 135.700 153.136 134.524 1.00 54.78  ? 129 SER A C   1 
ATOM   4972 O  O   . SER B 1 129 ? 135.886 152.337 133.599 1.00 54.78  ? 129 SER A O   1 
ATOM   4973 C  CB  . SER B 1 129 ? 136.632 155.461 134.443 1.00 54.78  ? 129 SER A CB  1 
ATOM   4974 O  OG  . SER B 1 129 ? 137.726 154.972 133.690 1.00 54.78  ? 129 SER A OG  1 
ATOM   4975 N  N   . SER B 1 130 ? 135.757 152.767 135.806 1.00 53.19  ? 130 SER A N   1 
ATOM   4976 C  CA  . SER B 1 130 ? 136.032 151.379 136.156 1.00 53.19  ? 130 SER A CA  1 
ATOM   4977 C  C   . SER B 1 130 ? 134.929 150.457 135.656 1.00 53.19  ? 130 SER A C   1 
ATOM   4978 O  O   . SER B 1 130 ? 135.208 149.383 135.108 1.00 53.19  ? 130 SER A O   1 
ATOM   4979 C  CB  . SER B 1 130 ? 136.200 151.244 137.668 1.00 53.19  ? 130 SER A CB  1 
ATOM   4980 O  OG  . SER B 1 130 ? 135.019 151.635 138.344 1.00 53.19  ? 130 SER A OG  1 
ATOM   4981 N  N   . THR B 1 131 ? 133.667 150.863 135.825 1.00 52.99  ? 131 THR A N   1 
ATOM   4982 C  CA  . THR B 1 131 ? 132.562 150.026 135.371 1.00 52.99  ? 131 THR A CA  1 
ATOM   4983 C  C   . THR B 1 131 ? 132.581 149.860 133.858 1.00 52.99  ? 131 THR A C   1 
ATOM   4984 O  O   . THR B 1 131 ? 132.357 148.758 133.348 1.00 52.99  ? 131 THR A O   1 
ATOM   4985 C  CB  . THR B 1 131 ? 131.231 150.617 135.829 1.00 52.99  ? 131 THR A CB  1 
ATOM   4986 O  OG1 . THR B 1 131 ? 131.256 150.804 137.249 1.00 52.99  ? 131 THR A OG1 1 
ATOM   4987 C  CG2 . THR B 1 131 ? 130.093 149.683 135.476 1.00 52.99  ? 131 THR A CG2 1 
ATOM   4988 N  N   . ALA B 1 132 ? 132.854 150.940 133.121 1.00 52.07  ? 132 ALA A N   1 
ATOM   4989 C  CA  . ALA B 1 132 ? 132.915 150.842 131.666 1.00 52.07  ? 132 ALA A CA  1 
ATOM   4990 C  C   . ALA B 1 132 ? 134.065 149.949 131.219 1.00 52.07  ? 132 ALA A C   1 
ATOM   4991 O  O   . ALA B 1 132 ? 133.903 149.116 130.318 1.00 52.07  ? 132 ALA A O   1 
ATOM   4992 C  CB  . ALA B 1 132 ? 133.046 152.233 131.051 1.00 52.07  ? 132 ALA A CB  1 
ATOM   4993 N  N   . PHE B 1 133 ? 135.237 150.104 131.841 1.00 50.87  ? 133 PHE A N   1 
ATOM   4994 C  CA  . PHE B 1 133 ? 136.377 149.279 131.460 1.00 50.87  ? 133 PHE A CA  1 
ATOM   4995 C  C   . PHE B 1 133 ? 136.103 147.807 131.728 1.00 50.87  ? 133 PHE A C   1 
ATOM   4996 O  O   . PHE B 1 133 ? 136.447 146.946 130.911 1.00 50.87  ? 133 PHE A O   1 
ATOM   4997 C  CB  . PHE B 1 133 ? 137.631 149.736 132.201 1.00 50.87  ? 133 PHE A CB  1 
ATOM   4998 C  CG  . PHE B 1 133 ? 138.877 149.021 131.771 1.00 50.87  ? 133 PHE A CG  1 
ATOM   4999 C  CD1 . PHE B 1 133 ? 139.584 149.446 130.662 1.00 50.87  ? 133 PHE A CD1 1 
ATOM   5000 C  CD2 . PHE B 1 133 ? 139.336 147.919 132.470 1.00 50.87  ? 133 PHE A CD2 1 
ATOM   5001 C  CE1 . PHE B 1 133 ? 140.728 148.789 130.262 1.00 50.87  ? 133 PHE A CE1 1 
ATOM   5002 C  CE2 . PHE B 1 133 ? 140.477 147.258 132.074 1.00 50.87  ? 133 PHE A CE2 1 
ATOM   5003 C  CZ  . PHE B 1 133 ? 141.174 147.694 130.969 1.00 50.87  ? 133 PHE A CZ  1 
ATOM   5004 N  N   . LEU B 1 134 ? 135.486 147.494 132.870 1.00 52.02  ? 134 LEU A N   1 
ATOM   5005 C  CA  . LEU B 1 134 ? 135.156 146.103 133.160 1.00 52.02  ? 134 LEU A CA  1 
ATOM   5006 C  C   . LEU B 1 134 ? 134.094 145.570 132.205 1.00 52.02  ? 134 LEU A C   1 
ATOM   5007 O  O   . LEU B 1 134 ? 134.190 144.430 131.739 1.00 52.02  ? 134 LEU A O   1 
ATOM   5008 C  CB  . LEU B 1 134 ? 134.698 145.962 134.609 1.00 52.02  ? 134 LEU A CB  1 
ATOM   5009 C  CG  . LEU B 1 134 ? 135.764 146.290 135.651 1.00 52.02  ? 134 LEU A CG  1 
ATOM   5010 C  CD1 . LEU B 1 134 ? 135.180 146.235 137.050 1.00 52.02  ? 134 LEU A CD1 1 
ATOM   5011 C  CD2 . LEU B 1 134 ? 136.939 145.342 135.514 1.00 52.02  ? 134 LEU A CD2 1 
ATOM   5012 N  N   . SER B 1 135 ? 133.078 146.379 131.897 1.00 50.90  ? 135 SER A N   1 
ATOM   5013 C  CA  . SER B 1 135 ? 132.013 145.947 131.002 1.00 50.90  ? 135 SER A CA  1 
ATOM   5014 C  C   . SER B 1 135 ? 132.468 145.829 129.556 1.00 50.90  ? 135 SER A C   1 
ATOM   5015 O  O   . SER B 1 135 ? 131.748 145.233 128.749 1.00 50.90  ? 135 SER A O   1 
ATOM   5016 C  CB  . SER B 1 135 ? 130.832 146.912 131.089 1.00 50.90  ? 135 SER A CB  1 
ATOM   5017 O  OG  . SER B 1 135 ? 129.847 146.589 130.125 1.00 50.90  ? 135 SER A OG  1 
ATOM   5018 N  N   . MET B 1 136 ? 133.624 146.398 129.207 1.00 48.62  ? 136 MET A N   1 
ATOM   5019 C  CA  . MET B 1 136 ? 134.161 146.191 127.865 1.00 48.62  ? 136 MET A CA  1 
ATOM   5020 C  C   . MET B 1 136 ? 134.372 144.709 127.577 1.00 48.62  ? 136 MET A C   1 
ATOM   5021 O  O   . MET B 1 136 ? 134.072 144.235 126.476 1.00 48.62  ? 136 MET A O   1 
ATOM   5022 C  CB  . MET B 1 136 ? 135.473 146.955 127.696 1.00 48.62  ? 136 MET A CB  1 
ATOM   5023 C  CG  . MET B 1 136 ? 135.303 148.420 127.355 1.00 48.62  ? 136 MET A CG  1 
ATOM   5024 S  SD  . MET B 1 136 ? 136.701 149.078 126.431 1.00 48.62  ? 136 MET A SD  1 
ATOM   5025 C  CE  . MET B 1 136 ? 138.064 148.290 127.278 1.00 48.62  ? 136 MET A CE  1 
ATOM   5026 N  N   . TRP B 1 137 ? 134.883 143.961 128.555 1.00 50.62  ? 137 TRP A N   1 
ATOM   5027 C  CA  . TRP B 1 137 ? 135.145 142.534 128.402 1.00 50.62  ? 137 TRP A CA  1 
ATOM   5028 C  C   . TRP B 1 137 ? 134.074 141.667 129.052 1.00 50.62  ? 137 TRP A C   1 
ATOM   5029 O  O   . TRP B 1 137 ? 133.542 140.756 128.413 1.00 50.62  ? 137 TRP A O   1 
ATOM   5030 C  CB  . TRP B 1 137 ? 136.520 142.190 128.984 1.00 50.62  ? 137 TRP A CB  1 
ATOM   5031 C  CG  . TRP B 1 137 ? 137.557 143.213 128.669 1.00 50.62  ? 137 TRP A CG  1 
ATOM   5032 C  CD1 . TRP B 1 137 ? 138.029 144.183 129.500 1.00 50.62  ? 137 TRP A CD1 1 
ATOM   5033 C  CD2 . TRP B 1 137 ? 138.249 143.376 127.426 1.00 50.62  ? 137 TRP A CD2 1 
ATOM   5034 N  NE1 . TRP B 1 137 ? 138.975 144.940 128.854 1.00 50.62  ? 137 TRP A NE1 1 
ATOM   5035 C  CE2 . TRP B 1 137 ? 139.128 144.465 127.579 1.00 50.62  ? 137 TRP A CE2 1 
ATOM   5036 C  CE3 . TRP B 1 137 ? 138.211 142.707 126.201 1.00 50.62  ? 137 TRP A CE3 1 
ATOM   5037 C  CZ2 . TRP B 1 137 ? 139.962 144.899 126.553 1.00 50.62  ? 137 TRP A CZ2 1 
ATOM   5038 C  CZ3 . TRP B 1 137 ? 139.038 143.140 125.184 1.00 50.62  ? 137 TRP A CZ3 1 
ATOM   5039 C  CH2 . TRP B 1 137 ? 139.902 144.225 125.365 1.00 50.62  ? 137 TRP A CH2 1 
ATOM   5040 N  N   . LEU B 1 138 ? 133.748 141.931 130.315 1.00 50.79  ? 138 LEU A N   1 
ATOM   5041 C  CA  . LEU B 1 138 ? 132.716 141.173 131.003 1.00 50.79  ? 138 LEU A CA  1 
ATOM   5042 C  C   . LEU B 1 138 ? 131.340 141.530 130.440 1.00 50.79  ? 138 LEU A C   1 
ATOM   5043 O  O   . LEU B 1 138 ? 131.199 142.361 129.540 1.00 50.79  ? 138 LEU A O   1 
ATOM   5044 C  CB  . LEU B 1 138 ? 132.776 141.440 132.505 1.00 50.79  ? 138 LEU A CB  1 
ATOM   5045 C  CG  . LEU B 1 138 ? 133.852 140.706 133.307 1.00 50.79  ? 138 LEU A CG  1 
ATOM   5046 C  CD1 . LEU B 1 138 ? 134.264 141.521 134.520 1.00 50.79  ? 138 LEU A CD1 1 
ATOM   5047 C  CD2 . LEU B 1 138 ? 133.358 139.334 133.731 1.00 50.79  ? 138 LEU A CD2 1 
ATOM   5048 N  N   . SER B 1 139 ? 130.311 140.888 130.979 1.00 52.88  ? 139 SER A N   1 
ATOM   5049 C  CA  . SER B 1 139 ? 128.941 141.178 130.588 1.00 52.88  ? 139 SER A CA  1 
ATOM   5050 C  C   . SER B 1 139 ? 128.394 142.335 131.413 1.00 52.88  ? 139 SER A C   1 
ATOM   5051 O  O   . SER B 1 139 ? 128.827 142.574 132.543 1.00 52.88  ? 139 SER A O   1 
ATOM   5052 C  CB  . SER B 1 139 ? 128.054 139.945 130.763 1.00 52.88  ? 139 SER A CB  1 
ATOM   5053 O  OG  . SER B 1 139 ? 126.825 140.103 130.076 1.00 52.88  ? 139 SER A OG  1 
ATOM   5054 N  N   . ASN B 1 140 ? 127.433 143.057 130.832 1.00 53.82  ? 140 ASN A N   1 
ATOM   5055 C  CA  . ASN B 1 140 ? 126.852 144.206 131.520 1.00 53.82  ? 140 ASN A CA  1 
ATOM   5056 C  C   . ASN B 1 140 ? 126.182 143.789 132.822 1.00 53.82  ? 140 ASN A C   1 
ATOM   5057 O  O   . ASN B 1 140 ? 126.364 144.438 133.861 1.00 53.82  ? 140 ASN A O   1 
ATOM   5058 C  CB  . ASN B 1 140 ? 125.846 144.907 130.608 1.00 53.82  ? 140 ASN A CB  1 
ATOM   5059 C  CG  . ASN B 1 140 ? 126.504 145.596 129.433 1.00 53.82  ? 140 ASN A CG  1 
ATOM   5060 O  OD1 . ASN B 1 140 ? 127.707 145.466 129.217 1.00 53.82  ? 140 ASN A OD1 1 
ATOM   5061 N  ND2 . ASN B 1 140 ? 125.715 146.331 128.661 1.00 53.82  ? 140 ASN A ND2 1 
ATOM   5062 N  N   . THR B 1 141 ? 125.409 142.702 132.786 1.00 56.01  ? 141 THR A N   1 
ATOM   5063 C  CA  . THR B 1 141 ? 124.692 142.246 133.972 1.00 56.01  ? 141 THR A CA  1 
ATOM   5064 C  C   . THR B 1 141 ? 125.655 141.891 135.096 1.00 56.01  ? 141 THR A C   1 
ATOM   5065 O  O   . THR B 1 141 ? 125.504 142.358 136.232 1.00 56.01  ? 141 THR A O   1 
ATOM   5066 C  CB  . THR B 1 141 ? 123.819 141.044 133.613 1.00 56.01  ? 141 THR A CB  1 
ATOM   5067 O  OG1 . THR B 1 141 ? 122.844 141.433 132.639 1.00 56.01  ? 141 THR A OG1 1 
ATOM   5068 C  CG2 . THR B 1 141 ? 123.116 140.504 134.842 1.00 56.01  ? 141 THR A CG2 1 
ATOM   5069 N  N   . SER B 1 142 ? 126.659 141.063 134.795 1.00 57.29  ? 142 SER A N   1 
ATOM   5070 C  CA  . SER B 1 142 ? 127.616 140.651 135.816 1.00 57.29  ? 142 SER A CA  1 
ATOM   5071 C  C   . SER B 1 142 ? 128.427 141.835 136.323 1.00 57.29  ? 142 SER A C   1 
ATOM   5072 O  O   . SER B 1 142 ? 128.674 141.956 137.529 1.00 57.29  ? 142 SER A O   1 
ATOM   5073 C  CB  . SER B 1 142 ? 128.540 139.568 135.261 1.00 57.29  ? 142 SER A CB  1 
ATOM   5074 O  OG  . SER B 1 142 ? 127.796 138.543 134.628 1.00 57.29  ? 142 SER A OG  1 
ATOM   5075 N  N   . THR B 1 143 ? 128.850 142.720 135.417 1.00 54.61  ? 143 THR A N   1 
ATOM   5076 C  CA  . THR B 1 143 ? 129.632 143.880 135.829 1.00 54.61  ? 143 THR A CA  1 
ATOM   5077 C  C   . THR B 1 143 ? 128.843 144.768 136.780 1.00 54.61  ? 143 THR A C   1 
ATOM   5078 O  O   . THR B 1 143 ? 129.361 145.186 137.822 1.00 54.61  ? 143 THR A O   1 
ATOM   5079 C  CB  . THR B 1 143 ? 130.078 144.678 134.606 1.00 54.61  ? 143 THR A CB  1 
ATOM   5080 O  OG1 . THR B 1 143 ? 130.835 143.832 133.735 1.00 54.61  ? 143 THR A OG1 1 
ATOM   5081 C  CG2 . THR B 1 143 ? 130.935 145.854 135.027 1.00 54.61  ? 143 THR A CG2 1 
ATOM   5082 N  N   . ALA B 1 144 ? 127.584 145.061 136.446 1.00 58.99  ? 144 ALA A N   1 
ATOM   5083 C  CA  . ALA B 1 144 ? 126.769 145.885 137.332 1.00 58.99  ? 144 ALA A CA  1 
ATOM   5084 C  C   . ALA B 1 144 ? 126.517 145.187 138.663 1.00 58.99  ? 144 ALA A C   1 
ATOM   5085 O  O   . ALA B 1 144 ? 126.656 145.802 139.728 1.00 58.99  ? 144 ALA A O   1 
ATOM   5086 C  CB  . ALA B 1 144 ? 125.448 146.242 136.654 1.00 58.99  ? 144 ALA A CB  1 
ATOM   5087 N  N   . ALA B 1 145 ? 126.161 143.898 138.625 1.00 60.74  ? 145 ALA A N   1 
ATOM   5088 C  CA  . ALA B 1 145 ? 125.855 143.170 139.849 1.00 60.74  ? 145 ALA A CA  1 
ATOM   5089 C  C   . ALA B 1 145 ? 127.071 143.005 140.747 1.00 60.74  ? 145 ALA A C   1 
ATOM   5090 O  O   . ALA B 1 145 ? 126.910 142.814 141.957 1.00 60.74  ? 145 ALA A O   1 
ATOM   5091 C  CB  . ALA B 1 145 ? 125.270 141.799 139.514 1.00 60.74  ? 145 ALA A CB  1 
ATOM   5092 N  N   . MET B 1 146 ? 128.278 143.066 140.189 1.00 63.70  ? 146 MET A N   1 
ATOM   5093 C  CA  . MET B 1 146 ? 129.484 142.996 141.000 1.00 63.70  ? 146 MET A CA  1 
ATOM   5094 C  C   . MET B 1 146 ? 129.892 144.366 141.531 1.00 63.70  ? 146 MET A C   1 
ATOM   5095 O  O   . MET B 1 146 ? 130.259 144.495 142.703 1.00 63.70  ? 146 MET A O   1 
ATOM   5096 C  CB  . MET B 1 146 ? 130.624 142.378 140.184 1.00 63.70  ? 146 MET A CB  1 
ATOM   5097 C  CG  . MET B 1 146 ? 131.996 142.476 140.830 1.00 63.70  ? 146 MET A CG  1 
ATOM   5098 S  SD  . MET B 1 146 ? 132.916 143.940 140.318 1.00 63.70  ? 146 MET A SD  1 
ATOM   5099 C  CE  . MET B 1 146 ? 133.037 143.658 138.555 1.00 63.70  ? 146 MET A CE  1 
ATOM   5100 N  N   . VAL B 1 147 ? 129.834 145.396 140.683 1.00 61.11  ? 147 VAL A N   1 
ATOM   5101 C  CA  . VAL B 1 147 ? 130.292 146.719 141.091 1.00 61.11  ? 147 VAL A CA  1 
ATOM   5102 C  C   . VAL B 1 147 ? 129.344 147.350 142.103 1.00 61.11  ? 147 VAL A C   1 
ATOM   5103 O  O   . VAL B 1 147 ? 129.791 148.042 143.026 1.00 61.11  ? 147 VAL A O   1 
ATOM   5104 C  CB  . VAL B 1 147 ? 130.486 147.617 139.856 1.00 61.11  ? 147 VAL A CB  1 
ATOM   5105 C  CG1 . VAL B 1 147 ? 130.802 149.039 140.273 1.00 61.11  ? 147 VAL A CG1 1 
ATOM   5106 C  CG2 . VAL B 1 147 ? 131.603 147.076 138.987 1.00 61.11  ? 147 VAL A CG2 1 
ATOM   5107 N  N   . MET B 1 148 ? 128.034 147.130 141.963 1.00 65.14  ? 148 MET A N   1 
ATOM   5108 C  CA  . MET B 1 148 ? 127.072 147.840 142.806 1.00 65.14  ? 148 MET A CA  1 
ATOM   5109 C  C   . MET B 1 148 ? 127.286 147.635 144.303 1.00 65.14  ? 148 MET A C   1 
ATOM   5110 O  O   . MET B 1 148 ? 127.242 148.632 145.045 1.00 65.14  ? 148 MET A O   1 
ATOM   5111 C  CB  . MET B 1 148 ? 125.648 147.457 142.392 1.00 65.14  ? 148 MET A CB  1 
ATOM   5112 C  CG  . MET B 1 148 ? 124.575 148.095 143.252 1.00 65.14  ? 148 MET A CG  1 
ATOM   5113 S  SD  . MET B 1 148 ? 124.792 149.875 143.414 1.00 65.14  ? 148 MET A SD  1 
ATOM   5114 C  CE  . MET B 1 148 ? 123.911 150.445 141.970 1.00 65.14  ? 148 MET A CE  1 
ATOM   5115 N  N   . PRO B 1 149 ? 127.490 146.415 144.821 1.00 67.12  ? 149 PRO A N   1 
ATOM   5116 C  CA  . PRO B 1 149 ? 127.714 146.289 146.274 1.00 67.12  ? 149 PRO A CA  1 
ATOM   5117 C  C   . PRO B 1 149 ? 128.913 147.075 146.774 1.00 67.12  ? 149 PRO A C   1 
ATOM   5118 O  O   . PRO B 1 149 ? 128.860 147.656 147.868 1.00 67.12  ? 149 PRO A O   1 
ATOM   5119 C  CB  . PRO B 1 149 ? 127.909 144.779 146.464 1.00 67.12  ? 149 PRO A CB  1 
ATOM   5120 C  CG  . PRO B 1 149 ? 127.181 144.166 145.332 1.00 67.12  ? 149 PRO A CG  1 
ATOM   5121 C  CD  . PRO B 1 149 ? 127.392 145.093 144.177 1.00 67.12  ? 149 PRO A CD  1 
ATOM   5122 N  N   . ILE B 1 150 ? 129.995 147.117 145.995 1.00 68.09  ? 150 ILE A N   1 
ATOM   5123 C  CA  . ILE B 1 150 ? 131.185 147.854 146.409 1.00 68.09  ? 150 ILE A CA  1 
ATOM   5124 C  C   . ILE B 1 150 ? 130.867 149.337 146.544 1.00 68.09  ? 150 ILE A C   1 
ATOM   5125 O  O   . ILE B 1 150 ? 131.217 149.978 147.541 1.00 68.09  ? 150 ILE A O   1 
ATOM   5126 C  CB  . ILE B 1 150 ? 132.338 147.613 145.419 1.00 68.09  ? 150 ILE A CB  1 
ATOM   5127 C  CG1 . ILE B 1 150 ? 132.793 146.154 145.474 1.00 68.09  ? 150 ILE A CG1 1 
ATOM   5128 C  CG2 . ILE B 1 150 ? 133.495 148.547 145.714 1.00 68.09  ? 150 ILE A CG2 1 
ATOM   5129 C  CD1 . ILE B 1 150 ? 133.472 145.682 144.209 1.00 68.09  ? 150 ILE A CD1 1 
ATOM   5130 N  N   . ALA B 1 151 ? 130.186 149.901 145.545 1.00 73.17  ? 151 ALA A N   1 
ATOM   5131 C  CA  . ALA B 1 151 ? 129.835 151.315 145.599 1.00 73.17  ? 151 ALA A CA  1 
ATOM   5132 C  C   . ALA B 1 151 ? 128.856 151.599 146.728 1.00 73.17  ? 151 ALA A C   1 
ATOM   5133 O  O   . ALA B 1 151 ? 128.918 152.660 147.359 1.00 73.17  ? 151 ALA A O   1 
ATOM   5134 C  CB  . ALA B 1 151 ? 129.250 151.766 144.265 1.00 73.17  ? 151 ALA A CB  1 
ATOM   5135 N  N   . GLU B 1 152 ? 127.930 150.673 146.983 1.00 80.30  ? 152 GLU A N   1 
ATOM   5136 C  CA  . GLU B 1 152 ? 126.998 150.855 148.090 1.00 80.30  ? 152 GLU A CA  1 
ATOM   5137 C  C   . GLU B 1 152 ? 127.739 150.909 149.419 1.00 80.30  ? 152 GLU A C   1 
ATOM   5138 O  O   . GLU B 1 152 ? 127.452 151.763 150.266 1.00 80.30  ? 152 GLU A O   1 
ATOM   5139 C  CB  . GLU B 1 152 ? 125.960 149.734 148.091 1.00 80.30  ? 152 GLU A CB  1 
ATOM   5140 C  CG  . GLU B 1 152 ? 124.848 149.917 149.108 1.00 80.30  ? 152 GLU A CG  1 
ATOM   5141 C  CD  . GLU B 1 152 ? 123.918 151.061 148.753 1.00 80.30  ? 152 GLU A CD  1 
ATOM   5142 O  OE1 . GLU B 1 152 ? 123.799 151.382 147.552 1.00 80.30  ? 152 GLU A OE1 1 
ATOM   5143 O  OE2 . GLU B 1 152 ? 123.307 151.639 149.676 1.00 80.30  ? 152 GLU A OE2 1 
ATOM   5144 N  N   . ALA B 1 153 ? 128.714 150.018 149.611 1.00 81.75  ? 153 ALA A N   1 
ATOM   5145 C  CA  . ALA B 1 153 ? 129.528 150.068 150.821 1.00 81.75  ? 153 ALA A CA  1 
ATOM   5146 C  C   . ALA B 1 153 ? 130.313 151.373 150.899 1.00 81.75  ? 153 ALA A C   1 
ATOM   5147 O  O   . ALA B 1 153 ? 130.407 151.997 151.964 1.00 81.75  ? 153 ALA A O   1 
ATOM   5148 C  CB  . ALA B 1 153 ? 130.468 148.864 150.869 1.00 81.75  ? 153 ALA A CB  1 
ATOM   5149 N  N   . VAL B 1 154 ? 130.882 151.806 149.773 1.00 82.88  ? 154 VAL A N   1 
ATOM   5150 C  CA  . VAL B 1 154 ? 131.672 153.032 149.775 1.00 82.88  ? 154 VAL A CA  1 
ATOM   5151 C  C   . VAL B 1 154 ? 130.816 154.225 150.176 1.00 82.88  ? 154 VAL A C   1 
ATOM   5152 O  O   . VAL B 1 154 ? 131.224 155.039 151.010 1.00 82.88  ? 154 VAL A O   1 
ATOM   5153 C  CB  . VAL B 1 154 ? 132.334 153.254 148.405 1.00 82.88  ? 154 VAL A CB  1 
ATOM   5154 C  CG1 . VAL B 1 154 ? 133.036 154.598 148.382 1.00 82.88  ? 154 VAL A CG1 1 
ATOM   5155 C  CG2 . VAL B 1 154 ? 133.326 152.149 148.120 1.00 82.88  ? 154 VAL A CG2 1 
ATOM   5156 N  N   . VAL B 1 155 ? 129.617 154.347 149.602 1.00 87.05  ? 155 VAL A N   1 
ATOM   5157 C  CA  . VAL B 1 155 ? 128.771 155.490 149.929 1.00 87.05  ? 155 VAL A CA  1 
ATOM   5158 C  C   . VAL B 1 155 ? 128.257 155.390 151.362 1.00 87.05  ? 155 VAL A C   1 
ATOM   5159 O  O   . VAL B 1 155 ? 128.144 156.403 152.063 1.00 87.05  ? 155 VAL A O   1 
ATOM   5160 C  CB  . VAL B 1 155 ? 127.626 155.647 148.909 1.00 87.05  ? 155 VAL A CB  1 
ATOM   5161 C  CG1 . VAL B 1 155 ? 128.187 155.905 147.519 1.00 87.05  ? 155 VAL A CG1 1 
ATOM   5162 C  CG2 . VAL B 1 155 ? 126.712 154.438 148.906 1.00 87.05  ? 155 VAL A CG2 1 
ATOM   5163 N  N   . GLN B 1 156 ? 127.955 154.174 151.831 1.00 93.19  ? 156 GLN A N   1 
ATOM   5164 C  CA  . GLN B 1 156 ? 127.463 154.022 153.196 1.00 93.19  ? 156 GLN A CA  1 
ATOM   5165 C  C   . GLN B 1 156 ? 128.510 154.451 154.216 1.00 93.19  ? 156 GLN A C   1 
ATOM   5166 O  O   . GLN B 1 156 ? 128.193 155.159 155.178 1.00 93.19  ? 156 GLN A O   1 
ATOM   5167 C  CB  . GLN B 1 156 ? 127.032 152.576 153.441 1.00 93.19  ? 156 GLN A CB  1 
ATOM   5168 C  CG  . GLN B 1 156 ? 126.025 152.396 154.573 1.00 93.19  ? 156 GLN A CG  1 
ATOM   5169 C  CD  . GLN B 1 156 ? 125.049 153.555 154.704 1.00 93.19  ? 156 GLN A CD  1 
ATOM   5170 O  OE1 . GLN B 1 156 ? 124.432 153.983 153.726 1.00 93.19  ? 156 GLN A OE1 1 
ATOM   5171 N  NE2 . GLN B 1 156 ? 124.907 154.070 155.919 1.00 93.19  ? 156 GLN A NE2 1 
ATOM   5172 N  N   . GLN B 1 157 ? 129.763 154.036 154.025 1.00 92.91  ? 157 GLN A N   1 
ATOM   5173 C  CA  . GLN B 1 157 ? 130.819 154.454 154.943 1.00 92.91  ? 157 GLN A CA  1 
ATOM   5174 C  C   . GLN B 1 157 ? 131.315 155.880 154.720 1.00 92.91  ? 157 GLN A C   1 
ATOM   5175 O  O   . GLN B 1 157 ? 131.830 156.483 155.667 1.00 92.91  ? 157 GLN A O   1 
ATOM   5176 C  CB  . GLN B 1 157 ? 131.986 153.463 154.897 1.00 92.91  ? 157 GLN A CB  1 
ATOM   5177 C  CG  . GLN B 1 157 ? 131.752 152.166 155.684 1.00 92.91  ? 157 GLN A CG  1 
ATOM   5178 C  CD  . GLN B 1 157 ? 130.975 151.103 154.940 1.00 92.91  ? 157 GLN A CD  1 
ATOM   5179 O  OE1 . GLN B 1 157 ? 129.908 151.368 154.393 1.00 92.91  ? 157 GLN A OE1 1 
ATOM   5180 N  NE2 . GLN B 1 157 ? 131.510 149.888 154.915 1.00 92.91  ? 157 GLN A NE2 1 
ATOM   5181 N  N   . ILE B 1 158 ? 131.188 156.442 153.515 1.00 95.74  ? 158 ILE A N   1 
ATOM   5182 C  CA  . ILE B 1 158 ? 131.564 157.845 153.360 1.00 95.74  ? 158 ILE A CA  1 
ATOM   5183 C  C   . ILE B 1 158 ? 130.518 158.748 154.004 1.00 95.74  ? 158 ILE A C   1 
ATOM   5184 O  O   . ILE B 1 158 ? 130.857 159.800 154.562 1.00 95.74  ? 158 ILE A O   1 
ATOM   5185 C  CB  . ILE B 1 158 ? 131.797 158.212 151.880 1.00 95.74  ? 158 ILE A CB  1 
ATOM   5186 C  CG1 . ILE B 1 158 ? 132.435 159.595 151.768 1.00 95.74  ? 158 ILE A CG1 1 
ATOM   5187 C  CG2 . ILE B 1 158 ? 130.507 158.239 151.104 1.00 95.74  ? 158 ILE A CG2 1 
ATOM   5188 C  CD1 . ILE B 1 158 ? 132.984 159.898 150.393 1.00 95.74  ? 158 ILE A CD1 1 
ATOM   5189 N  N   . ILE B 1 159 ? 129.240 158.364 153.949 1.00 97.40  ? 159 ILE A N   1 
ATOM   5190 C  CA  . ILE B 1 159 ? 128.208 159.181 154.575 1.00 97.40  ? 159 ILE A CA  1 
ATOM   5191 C  C   . ILE B 1 159 ? 128.123 158.925 156.074 1.00 97.40  ? 159 ILE A C   1 
ATOM   5192 O  O   . ILE B 1 159 ? 127.556 159.746 156.806 1.00 97.40  ? 159 ILE A O   1 
ATOM   5193 C  CB  . ILE B 1 159 ? 126.845 158.946 153.902 1.00 97.40  ? 159 ILE A CB  1 
ATOM   5194 C  CG1 . ILE B 1 159 ? 125.889 160.098 154.215 1.00 97.40  ? 159 ILE A CG1 1 
ATOM   5195 C  CG2 . ILE B 1 159 ? 126.240 157.628 154.357 1.00 97.40  ? 159 ILE A CG2 1 
ATOM   5196 C  CD1 . ILE B 1 159 ? 126.342 161.429 153.658 1.00 97.40  ? 159 ILE A CD1 1 
ATOM   5197 N  N   . ASN B 1 160 ? 128.687 157.816 156.556 1.00 100.15 ? 160 ASN A N   1 
ATOM   5198 C  CA  . ASN B 1 160 ? 128.706 157.545 157.988 1.00 100.15 ? 160 ASN A CA  1 
ATOM   5199 C  C   . ASN B 1 160 ? 129.654 158.464 158.747 1.00 100.15 ? 160 ASN A C   1 
ATOM   5200 O  O   . ASN B 1 160 ? 129.610 158.485 159.981 1.00 100.15 ? 160 ASN A O   1 
ATOM   5201 C  CB  . ASN B 1 160 ? 129.088 156.087 158.242 1.00 100.15 ? 160 ASN A CB  1 
ATOM   5202 C  CG  . ASN B 1 160 ? 127.888 155.163 158.237 1.00 100.15 ? 160 ASN A CG  1 
ATOM   5203 O  OD1 . ASN B 1 160 ? 126.744 155.614 158.270 1.00 100.15 ? 160 ASN A OD1 1 
ATOM   5204 N  ND2 . ASN B 1 160 ? 128.144 153.860 158.198 1.00 100.15 ? 160 ASN A ND2 1 
ATOM   5205 N  N   . ALA B 1 161 ? 130.502 159.212 158.048 1.00 101.62 ? 161 ALA A N   1 
ATOM   5206 C  CA  . ALA B 1 161 ? 131.424 160.136 158.696 1.00 101.62 ? 161 ALA A CA  1 
ATOM   5207 C  C   . ALA B 1 161 ? 130.959 161.576 158.514 1.00 101.62 ? 161 ALA A C   1 
ATOM   5208 O  O   . ALA B 1 161 ? 129.795 161.827 158.202 1.00 101.62 ? 161 ALA A O   1 
ATOM   5209 C  CB  . ALA B 1 161 ? 132.829 159.956 158.145 1.00 101.62 ? 161 ALA A CB  1 
ATOM   5210 N  N   . THR B 1 230 ? 120.026 163.653 156.522 1.00 98.40  ? 230 THR A N   1 
ATOM   5211 C  CA  . THR B 1 230 ? 121.044 164.014 155.541 1.00 98.40  ? 230 THR A CA  1 
ATOM   5212 C  C   . THR B 1 230 ? 120.637 163.569 154.141 1.00 98.40  ? 230 THR A C   1 
ATOM   5213 O  O   . THR B 1 230 ? 120.949 162.455 153.720 1.00 98.40  ? 230 THR A O   1 
ATOM   5214 C  CB  . THR B 1 230 ? 122.408 163.392 155.888 1.00 98.40  ? 230 THR A CB  1 
ATOM   5215 O  OG1 . THR B 1 230 ? 122.283 161.967 155.954 1.00 98.40  ? 230 THR A OG1 1 
ATOM   5216 C  CG2 . THR B 1 230 ? 122.905 163.914 157.227 1.00 98.40  ? 230 THR A CG2 1 
ATOM   5217 N  N   . LYS B 1 231 ? 119.937 164.449 153.421 1.00 96.57  ? 231 LYS A N   1 
ATOM   5218 C  CA  . LYS B 1 231 ? 119.516 164.128 152.062 1.00 96.57  ? 231 LYS A CA  1 
ATOM   5219 C  C   . LYS B 1 231 ? 120.685 164.101 151.087 1.00 96.57  ? 231 LYS A C   1 
ATOM   5220 O  O   . LYS B 1 231 ? 120.537 163.577 149.977 1.00 96.57  ? 231 LYS A O   1 
ATOM   5221 C  CB  . LYS B 1 231 ? 118.452 165.126 151.593 1.00 96.57  ? 231 LYS A CB  1 
ATOM   5222 C  CG  . LYS B 1 231 ? 118.915 166.578 151.514 1.00 96.57  ? 231 LYS A CG  1 
ATOM   5223 C  CD  . LYS B 1 231 ? 119.339 166.966 150.103 1.00 96.57  ? 231 LYS A CD  1 
ATOM   5224 C  CE  . LYS B 1 231 ? 119.677 168.445 150.011 1.00 96.57  ? 231 LYS A CE  1 
ATOM   5225 N  NZ  . LYS B 1 231 ? 120.096 168.832 148.636 1.00 96.57  ? 231 LYS A NZ  1 
ATOM   5226 N  N   . LYS B 1 232 ? 121.838 164.653 151.475 1.00 94.55  ? 232 LYS A N   1 
ATOM   5227 C  CA  . LYS B 1 232 ? 123.008 164.613 150.604 1.00 94.55  ? 232 LYS A CA  1 
ATOM   5228 C  C   . LYS B 1 232 ? 123.451 163.181 150.345 1.00 94.55  ? 232 LYS A C   1 
ATOM   5229 O  O   . LYS B 1 232 ? 123.822 162.833 149.218 1.00 94.55  ? 232 LYS A O   1 
ATOM   5230 C  CB  . LYS B 1 232 ? 124.148 165.427 151.216 1.00 94.55  ? 232 LYS A CB  1 
ATOM   5231 C  CG  . LYS B 1 232 ? 123.830 166.902 151.385 1.00 94.55  ? 232 LYS A CG  1 
ATOM   5232 C  CD  . LYS B 1 232 ? 123.379 167.525 150.073 1.00 94.55  ? 232 LYS A CD  1 
ATOM   5233 C  CE  . LYS B 1 232 ? 124.504 167.541 149.049 1.00 94.55  ? 232 LYS A CE  1 
ATOM   5234 N  NZ  . LYS B 1 232 ? 125.764 168.092 149.622 1.00 94.55  ? 232 LYS A NZ  1 
ATOM   5235 N  N   . GLY B 1 233 ? 123.420 162.335 151.376 1.00 90.38  ? 233 GLY A N   1 
ATOM   5236 C  CA  . GLY B 1 233 ? 123.747 160.934 151.175 1.00 90.38  ? 233 GLY A CA  1 
ATOM   5237 C  C   . GLY B 1 233 ? 122.784 160.244 150.230 1.00 90.38  ? 233 GLY A C   1 
ATOM   5238 O  O   . GLY B 1 233 ? 123.195 159.457 149.375 1.00 90.38  ? 233 GLY A O   1 
ATOM   5239 N  N   . HIS B 1 234 ? 121.489 160.539 150.363 1.00 88.31  ? 234 HIS A N   1 
ATOM   5240 C  CA  . HIS B 1 234 ? 120.492 159.961 149.466 1.00 88.31  ? 234 HIS A CA  1 
ATOM   5241 C  C   . HIS B 1 234 ? 120.738 160.390 148.025 1.00 88.31  ? 234 HIS A C   1 
ATOM   5242 O  O   . HIS B 1 234 ? 120.702 159.567 147.100 1.00 88.31  ? 234 HIS A O   1 
ATOM   5243 C  CB  . HIS B 1 234 ? 119.092 160.372 149.928 1.00 88.31  ? 234 HIS A CB  1 
ATOM   5244 C  CG  . HIS B 1 234 ? 117.987 159.879 149.045 1.00 88.31  ? 234 HIS A CG  1 
ATOM   5245 N  ND1 . HIS B 1 234 ? 117.661 158.545 148.935 1.00 88.31  ? 234 HIS A ND1 1 
ATOM   5246 C  CD2 . HIS B 1 234 ? 117.122 160.545 148.245 1.00 88.31  ? 234 HIS A CD2 1 
ATOM   5247 C  CE1 . HIS B 1 234 ? 116.648 158.409 148.098 1.00 88.31  ? 234 HIS A CE1 1 
ATOM   5248 N  NE2 . HIS B 1 234 ? 116.301 159.608 147.666 1.00 88.31  ? 234 HIS A NE2 1 
ATOM   5249 N  N   . VAL B 1 235 ? 121.009 161.681 147.818 1.00 82.27  ? 235 VAL A N   1 
ATOM   5250 C  CA  . VAL B 1 235 ? 121.247 162.185 146.468 1.00 82.27  ? 235 VAL A CA  1 
ATOM   5251 C  C   . VAL B 1 235 ? 122.507 161.565 145.879 1.00 82.27  ? 235 VAL A C   1 
ATOM   5252 O  O   . VAL B 1 235 ? 122.526 161.147 144.715 1.00 82.27  ? 235 VAL A O   1 
ATOM   5253 C  CB  . VAL B 1 235 ? 121.321 163.723 146.481 1.00 82.27  ? 235 VAL A CB  1 
ATOM   5254 C  CG1 . VAL B 1 235 ? 121.766 164.245 145.127 1.00 82.27  ? 235 VAL A CG1 1 
ATOM   5255 C  CG2 . VAL B 1 235 ? 119.975 164.311 146.865 1.00 82.27  ? 235 VAL A CG2 1 
ATOM   5256 N  N   . THR B 1 236 ? 123.578 161.487 146.673 1.00 78.64  ? 236 THR A N   1 
ATOM   5257 C  CA  . THR B 1 236 ? 124.822 160.906 146.180 1.00 78.64  ? 236 THR A CA  1 
ATOM   5258 C  C   . THR B 1 236 ? 124.648 159.429 145.856 1.00 78.64  ? 236 THR A C   1 
ATOM   5259 O  O   . THR B 1 236 ? 125.206 158.931 144.870 1.00 78.64  ? 236 THR A O   1 
ATOM   5260 C  CB  . THR B 1 236 ? 125.937 161.109 147.206 1.00 78.64  ? 236 THR A CB  1 
ATOM   5261 O  OG1 . THR B 1 236 ? 126.100 162.509 147.461 1.00 78.64  ? 236 THR A OG1 1 
ATOM   5262 C  CG2 . THR B 1 236 ? 127.248 160.546 146.686 1.00 78.64  ? 236 THR A CG2 1 
ATOM   5263 N  N   . ARG B 1 237 ? 123.883 158.706 146.676 1.00 79.02  ? 237 ARG A N   1 
ATOM   5264 C  CA  . ARG B 1 237 ? 123.652 157.293 146.406 1.00 79.02  ? 237 ARG A CA  1 
ATOM   5265 C  C   . ARG B 1 237 ? 122.838 157.103 145.132 1.00 79.02  ? 237 ARG A C   1 
ATOM   5266 O  O   . ARG B 1 237 ? 123.126 156.201 144.333 1.00 79.02  ? 237 ARG A O   1 
ATOM   5267 C  CB  . ARG B 1 237 ? 122.967 156.641 147.604 1.00 79.02  ? 237 ARG A CB  1 
ATOM   5268 C  CG  . ARG B 1 237 ? 123.135 155.137 147.657 1.00 79.02  ? 237 ARG A CG  1 
ATOM   5269 C  CD  . ARG B 1 237 ? 122.138 154.493 148.599 1.00 79.02  ? 237 ARG A CD  1 
ATOM   5270 N  NE  . ARG B 1 237 ? 122.595 154.498 149.984 1.00 79.02  ? 237 ARG A NE  1 
ATOM   5271 C  CZ  . ARG B 1 237 ? 122.326 155.454 150.863 1.00 79.02  ? 237 ARG A CZ  1 
ATOM   5272 N  NH1 . ARG B 1 237 ? 121.589 156.504 150.540 1.00 79.02  ? 237 ARG A NH1 1 
ATOM   5273 N  NH2 . ARG B 1 237 ? 122.804 155.350 152.100 1.00 79.02  ? 237 ARG A NH2 1 
ATOM   5274 N  N   . LYS B 1 238 ? 121.828 157.949 144.912 1.00 73.94  ? 238 LYS A N   1 
ATOM   5275 C  CA  . LYS B 1 238 ? 121.105 157.899 143.645 1.00 73.94  ? 238 LYS A CA  1 
ATOM   5276 C  C   . LYS B 1 238 ? 122.042 158.168 142.475 1.00 73.94  ? 238 LYS A C   1 
ATOM   5277 O  O   . LYS B 1 238 ? 121.987 157.477 141.448 1.00 73.94  ? 238 LYS A O   1 
ATOM   5278 C  CB  . LYS B 1 238 ? 119.960 158.910 143.646 1.00 73.94  ? 238 LYS A CB  1 
ATOM   5279 C  CG  . LYS B 1 238 ? 118.854 158.605 144.632 1.00 73.94  ? 238 LYS A CG  1 
ATOM   5280 C  CD  . LYS B 1 238 ? 118.042 159.851 144.931 1.00 73.94  ? 238 LYS A CD  1 
ATOM   5281 C  CE  . LYS B 1 238 ? 116.800 159.920 144.059 1.00 73.94  ? 238 LYS A CE  1 
ATOM   5282 N  NZ  . LYS B 1 238 ? 115.890 158.763 144.289 1.00 73.94  ? 238 LYS A NZ  1 
ATOM   5283 N  N   . LEU B 1 239 ? 122.917 159.164 142.623 1.00 67.53  ? 239 LEU A N   1 
ATOM   5284 C  CA  . LEU B 1 239 ? 123.848 159.513 141.557 1.00 67.53  ? 239 LEU A CA  1 
ATOM   5285 C  C   . LEU B 1 239 ? 124.765 158.345 141.222 1.00 67.53  ? 239 LEU A C   1 
ATOM   5286 O  O   . LEU B 1 239 ? 124.970 158.019 140.048 1.00 67.53  ? 239 LEU A O   1 
ATOM   5287 C  CB  . LEU B 1 239 ? 124.664 160.739 141.967 1.00 67.53  ? 239 LEU A CB  1 
ATOM   5288 C  CG  . LEU B 1 239 ? 125.838 161.152 141.080 1.00 67.53  ? 239 LEU A CG  1 
ATOM   5289 C  CD1 . LEU B 1 239 ? 125.394 161.311 139.639 1.00 67.53  ? 239 LEU A CD1 1 
ATOM   5290 C  CD2 . LEU B 1 239 ? 126.463 162.436 141.594 1.00 67.53  ? 239 LEU A CD2 1 
ATOM   5291 N  N   . THR B 1 240 ? 125.319 157.691 142.245 1.00 65.92  ? 240 THR A N   1 
ATOM   5292 C  CA  . THR B 1 240 ? 126.257 156.603 141.984 1.00 65.92  ? 240 THR A CA  1 
ATOM   5293 C  C   . THR B 1 240 ? 125.543 155.379 141.415 1.00 65.92  ? 240 THR A C   1 
ATOM   5294 O  O   . THR B 1 240 ? 126.077 154.702 140.525 1.00 65.92  ? 240 THR A O   1 
ATOM   5295 C  CB  . THR B 1 240 ? 127.050 156.255 143.249 1.00 65.92  ? 240 THR A CB  1 
ATOM   5296 O  OG1 . THR B 1 240 ? 128.085 155.320 142.921 1.00 65.92  ? 240 THR A OG1 1 
ATOM   5297 C  CG2 . THR B 1 240 ? 126.167 155.660 144.325 1.00 65.92  ? 240 THR A CG2 1 
ATOM   5298 N  N   . CYS B 1 241 ? 124.323 155.097 141.882 1.00 62.45  ? 241 CYS A N   1 
ATOM   5299 C  CA  . CYS B 1 241 ? 123.557 153.996 141.309 1.00 62.45  ? 241 CYS A CA  1 
ATOM   5300 C  C   . CYS B 1 241 ? 123.299 154.233 139.827 1.00 62.45  ? 241 CYS A C   1 
ATOM   5301 O  O   . CYS B 1 241 ? 123.541 153.354 138.987 1.00 62.45  ? 241 CYS A O   1 
ATOM   5302 C  CB  . CYS B 1 241 ? 122.240 153.829 142.064 1.00 62.45  ? 241 CYS A CB  1 
ATOM   5303 S  SG  . CYS B 1 241 ? 122.405 153.170 143.736 1.00 62.45  ? 241 CYS A SG  1 
ATOM   5304 N  N   . LEU B 1 242 ? 122.828 155.434 139.486 1.00 59.35  ? 242 LEU A N   1 
ATOM   5305 C  CA  . LEU B 1 242 ? 122.534 155.739 138.092 1.00 59.35  ? 242 LEU A CA  1 
ATOM   5306 C  C   . LEU B 1 242 ? 123.794 155.711 137.241 1.00 59.35  ? 242 LEU A C   1 
ATOM   5307 O  O   . LEU B 1 242 ? 123.770 155.226 136.104 1.00 59.35  ? 242 LEU A O   1 
ATOM   5308 C  CB  . LEU B 1 242 ? 121.845 157.096 137.988 1.00 59.35  ? 242 LEU A CB  1 
ATOM   5309 C  CG  . LEU B 1 242 ? 120.323 157.035 138.086 1.00 59.35  ? 242 LEU A CG  1 
ATOM   5310 C  CD1 . LEU B 1 242 ? 119.724 158.401 137.838 1.00 59.35  ? 242 LEU A CD1 1 
ATOM   5311 C  CD2 . LEU B 1 242 ? 119.774 156.019 137.101 1.00 59.35  ? 242 LEU A CD2 1 
ATOM   5312 N  N   . CYS B 1 243 ? 124.906 156.235 137.765 1.00 55.49  ? 243 CYS A N   1 
ATOM   5313 C  CA  . CYS B 1 243 ? 126.121 156.283 136.962 1.00 55.49  ? 243 CYS A CA  1 
ATOM   5314 C  C   . CYS B 1 243 ? 126.651 154.883 136.691 1.00 55.49  ? 243 CYS A C   1 
ATOM   5315 O  O   . CYS B 1 243 ? 127.102 154.597 135.579 1.00 55.49  ? 243 CYS A O   1 
ATOM   5316 C  CB  . CYS B 1 243 ? 127.188 157.141 137.639 1.00 55.49  ? 243 CYS A CB  1 
ATOM   5317 S  SG  . CYS B 1 243 ? 128.065 156.363 139.003 1.00 55.49  ? 243 CYS A SG  1 
ATOM   5318 N  N   . ILE B 1 244 ? 126.593 153.989 137.682 1.00 50.46  ? 244 ILE A N   1 
ATOM   5319 C  CA  . ILE B 1 244 ? 127.009 152.609 137.434 1.00 50.46  ? 244 ILE A CA  1 
ATOM   5320 C  C   . ILE B 1 244 ? 126.096 151.954 136.406 1.00 50.46  ? 244 ILE A C   1 
ATOM   5321 O  O   . ILE B 1 244 ? 126.563 151.292 135.464 1.00 50.46  ? 244 ILE A O   1 
ATOM   5322 C  CB  . ILE B 1 244 ? 127.038 151.812 138.748 1.00 50.46  ? 244 ILE A CB  1 
ATOM   5323 C  CG1 . ILE B 1 244 ? 128.212 152.259 139.609 1.00 50.46  ? 244 ILE A CG1 1 
ATOM   5324 C  CG2 . ILE B 1 244 ? 127.136 150.326 138.467 1.00 50.46  ? 244 ILE A CG2 1 
ATOM   5325 C  CD1 . ILE B 1 244 ? 128.251 151.580 140.936 1.00 50.46  ? 244 ILE A CD1 1 
ATOM   5326 N  N   . ALA B 1 245 ? 124.779 152.139 136.561 1.00 49.99  ? 245 ALA A N   1 
ATOM   5327 C  CA  . ALA B 1 245 ? 123.830 151.512 135.645 1.00 49.99  ? 245 ALA A CA  1 
ATOM   5328 C  C   . ALA B 1 245 ? 124.064 151.968 134.212 1.00 49.99  ? 245 ALA A C   1 
ATOM   5329 O  O   . ALA B 1 245 ? 124.005 151.163 133.276 1.00 49.99  ? 245 ALA A O   1 
ATOM   5330 C  CB  . ALA B 1 245 ? 122.398 151.829 136.071 1.00 49.99  ? 245 ALA A CB  1 
ATOM   5331 N  N   . TYR B 1 246 ? 124.326 153.261 134.020 1.00 49.92  ? 246 TYR A N   1 
ATOM   5332 C  CA  . TYR B 1 246 ? 124.525 153.779 132.671 1.00 49.92  ? 246 TYR A CA  1 
ATOM   5333 C  C   . TYR B 1 246 ? 125.897 153.407 132.123 1.00 49.92  ? 246 TYR A C   1 
ATOM   5334 O  O   . TYR B 1 246 ? 126.031 153.107 130.931 1.00 49.92  ? 246 TYR A O   1 
ATOM   5335 C  CB  . TYR B 1 246 ? 124.341 155.294 132.659 1.00 49.92  ? 246 TYR A CB  1 
ATOM   5336 C  CG  . TYR B 1 246 ? 122.926 155.753 132.948 1.00 49.92  ? 246 TYR A CG  1 
ATOM   5337 C  CD1 . TYR B 1 246 ? 121.893 154.842 133.106 1.00 49.92  ? 246 TYR A CD1 1 
ATOM   5338 C  CD2 . TYR B 1 246 ? 122.630 157.101 133.058 1.00 49.92  ? 246 TYR A CD2 1 
ATOM   5339 C  CE1 . TYR B 1 246 ? 120.606 155.258 133.365 1.00 49.92  ? 246 TYR A CE1 1 
ATOM   5340 C  CE2 . TYR B 1 246 ? 121.342 157.527 133.319 1.00 49.92  ? 246 TYR A CE2 1 
ATOM   5341 C  CZ  . TYR B 1 246 ? 120.334 156.602 133.471 1.00 49.92  ? 246 TYR A CZ  1 
ATOM   5342 O  OH  . TYR B 1 246 ? 119.053 157.024 133.730 1.00 49.92  ? 246 TYR A OH  1 
ATOM   5343 N  N   . SER B 1 247 ? 126.924 153.406 132.977 1.00 48.52  ? 247 SER A N   1 
ATOM   5344 C  CA  . SER B 1 247 ? 128.273 153.121 132.512 1.00 48.52  ? 247 SER A CA  1 
ATOM   5345 C  C   . SER B 1 247 ? 128.430 151.674 132.089 1.00 48.52  ? 247 SER A C   1 
ATOM   5346 O  O   . SER B 1 247 ? 129.212 151.388 131.179 1.00 48.52  ? 247 SER A O   1 
ATOM   5347 C  CB  . SER B 1 247 ? 129.285 153.464 133.598 1.00 48.52  ? 247 SER A CB  1 
ATOM   5348 O  OG  . SER B 1 247 ? 129.286 154.855 133.845 1.00 48.52  ? 247 SER A OG  1 
ATOM   5349 N  N   . SER B 1 248 ? 127.712 150.748 132.730 1.00 48.22  ? 248 SER A N   1 
ATOM   5350 C  CA  . SER B 1 248 ? 127.773 149.359 132.284 1.00 48.22  ? 248 SER A CA  1 
ATOM   5351 C  C   . SER B 1 248 ? 127.417 149.248 130.805 1.00 48.22  ? 248 SER A C   1 
ATOM   5352 O  O   . SER B 1 248 ? 128.189 148.708 130.001 1.00 48.22  ? 248 SER A O   1 
ATOM   5353 C  CB  . SER B 1 248 ? 126.837 148.497 133.128 1.00 48.22  ? 248 SER A CB  1 
ATOM   5354 O  OG  . SER B 1 248 ? 127.307 148.388 134.458 1.00 48.22  ? 248 SER A OG  1 
ATOM   5355 N  N   . THR B 1 249 ? 126.264 149.798 130.421 1.00 48.18  ? 249 THR A N   1 
ATOM   5356 C  CA  . THR B 1 249 ? 125.839 149.738 129.027 1.00 48.18  ? 249 THR A CA  1 
ATOM   5357 C  C   . THR B 1 249 ? 126.747 150.568 128.130 1.00 48.18  ? 249 THR A C   1 
ATOM   5358 O  O   . THR B 1 249 ? 127.065 150.149 127.013 1.00 48.18  ? 249 THR A O   1 
ATOM   5359 C  CB  . THR B 1 249 ? 124.393 150.204 128.896 1.00 48.18  ? 249 THR A CB  1 
ATOM   5360 O  OG1 . THR B 1 249 ? 124.279 151.527 129.420 1.00 48.18  ? 249 THR A OG1 1 
ATOM   5361 C  CG2 . THR B 1 249 ? 123.471 149.287 129.673 1.00 48.18  ? 249 THR A CG2 1 
ATOM   5362 N  N   . ILE B 1 250 ? 127.176 151.745 128.598 1.00 47.05  ? 250 ILE A N   1 
ATOM   5363 C  CA  . ILE B 1 250 ? 128.012 152.610 127.767 1.00 47.05  ? 250 ILE A CA  1 
ATOM   5364 C  C   . ILE B 1 250 ? 129.325 151.919 127.422 1.00 47.05  ? 250 ILE A C   1 
ATOM   5365 O  O   . ILE B 1 250 ? 129.796 151.984 126.281 1.00 47.05  ? 250 ILE A O   1 
ATOM   5366 C  CB  . ILE B 1 250 ? 128.250 153.961 128.466 1.00 47.05  ? 250 ILE A CB  1 
ATOM   5367 C  CG1 . ILE B 1 250 ? 127.007 154.842 128.363 1.00 47.05  ? 250 ILE A CG1 1 
ATOM   5368 C  CG2 . ILE B 1 250 ? 129.444 154.668 127.862 1.00 47.05  ? 250 ILE A CG2 1 
ATOM   5369 C  CD1 . ILE B 1 250 ? 127.017 156.011 129.318 1.00 47.05  ? 250 ILE A CD1 1 
ATOM   5370 N  N   . GLY B 1 251 ? 129.941 151.252 128.399 1.00 46.43  ? 251 GLY A N   1 
ATOM   5371 C  CA  . GLY B 1 251 ? 131.119 150.456 128.118 1.00 46.43  ? 251 GLY A CA  1 
ATOM   5372 C  C   . GLY B 1 251 ? 130.825 149.192 127.346 1.00 46.43  ? 251 GLY A C   1 
ATOM   5373 O  O   . GLY B 1 251 ? 131.734 148.633 126.724 1.00 46.43  ? 251 GLY A O   1 
ATOM   5374 N  N   . GLY B 1 252 ? 129.576 148.722 127.376 1.00 49.01  ? 252 GLY A N   1 
ATOM   5375 C  CA  . GLY B 1 252 ? 129.214 147.577 126.556 1.00 49.01  ? 252 GLY A CA  1 
ATOM   5376 C  C   . GLY B 1 252 ? 129.348 147.847 125.068 1.00 49.01  ? 252 GLY A C   1 
ATOM   5377 O  O   . GLY B 1 252 ? 129.677 146.948 124.292 1.00 49.01  ? 252 GLY A O   1 
ATOM   5378 N  N   . LEU B 1 253 ? 129.092 149.090 124.649 1.00 48.15  ? 253 LEU A N   1 
ATOM   5379 C  CA  . LEU B 1 253 ? 129.143 149.440 123.232 1.00 48.15  ? 253 LEU A CA  1 
ATOM   5380 C  C   . LEU B 1 253 ? 130.536 149.309 122.634 1.00 48.15  ? 253 LEU A C   1 
ATOM   5381 O  O   . LEU B 1 253 ? 130.657 149.082 121.426 1.00 48.15  ? 253 LEU A O   1 
ATOM   5382 C  CB  . LEU B 1 253 ? 128.660 150.876 123.020 1.00 48.15  ? 253 LEU A CB  1 
ATOM   5383 C  CG  . LEU B 1 253 ? 127.177 151.167 122.806 1.00 48.15  ? 253 LEU A CG  1 
ATOM   5384 C  CD1 . LEU B 1 253 ? 126.406 151.003 124.090 1.00 48.15  ? 253 LEU A CD1 1 
ATOM   5385 C  CD2 . LEU B 1 253 ? 127.008 152.574 122.266 1.00 48.15  ? 253 LEU A CD2 1 
ATOM   5386 N  N   . THR B 1 254 ? 131.586 149.458 123.443 1.00 49.17  ? 254 THR A N   1 
ATOM   5387 C  CA  . THR B 1 254 ? 132.922 149.659 122.891 1.00 49.17  ? 254 THR A CA  1 
ATOM   5388 C  C   . THR B 1 254 ? 133.423 148.430 122.139 1.00 49.17  ? 254 THR A C   1 
ATOM   5389 O  O   . THR B 1 254 ? 134.031 148.562 121.071 1.00 49.17  ? 254 THR A O   1 
ATOM   5390 C  CB  . THR B 1 254 ? 133.892 150.042 124.004 1.00 49.17  ? 254 THR A CB  1 
ATOM   5391 O  OG1 . THR B 1 254 ? 133.295 151.051 124.825 1.00 49.17  ? 254 THR A OG1 1 
ATOM   5392 C  CG2 . THR B 1 254 ? 135.172 150.590 123.414 1.00 49.17  ? 254 THR A CG2 1 
ATOM   5393 N  N   . THR B 1 255 ? 133.185 147.234 122.669 1.00 51.27  ? 255 THR A N   1 
ATOM   5394 C  CA  . THR B 1 255 ? 133.688 146.010 122.065 1.00 51.27  ? 255 THR A CA  1 
ATOM   5395 C  C   . THR B 1 255 ? 132.535 145.148 121.569 1.00 51.27  ? 255 THR A C   1 
ATOM   5396 O  O   . THR B 1 255 ? 131.384 145.312 121.981 1.00 51.27  ? 255 THR A O   1 
ATOM   5397 C  CB  . THR B 1 255 ? 134.543 145.206 123.051 1.00 51.27  ? 255 THR A CB  1 
ATOM   5398 O  OG1 . THR B 1 255 ? 133.805 144.988 124.259 1.00 51.27  ? 255 THR A OG1 1 
ATOM   5399 C  CG2 . THR B 1 255 ? 135.824 145.952 123.373 1.00 51.27  ? 255 THR A CG2 1 
ATOM   5400 N  N   . ILE B 1 256 ? 132.864 144.219 120.668 1.00 53.43  ? 256 ILE A N   1 
ATOM   5401 C  CA  . ILE B 1 256 ? 131.850 143.338 120.100 1.00 53.43  ? 256 ILE A CA  1 
ATOM   5402 C  C   . ILE B 1 256 ? 131.251 142.441 121.174 1.00 53.43  ? 256 ILE A C   1 
ATOM   5403 O  O   . ILE B 1 256 ? 130.038 142.206 121.200 1.00 53.43  ? 256 ILE A O   1 
ATOM   5404 C  CB  . ILE B 1 256 ? 132.440 142.510 118.946 1.00 53.43  ? 256 ILE A CB  1 
ATOM   5405 C  CG1 . ILE B 1 256 ? 133.003 143.424 117.862 1.00 53.43  ? 256 ILE A CG1 1 
ATOM   5406 C  CG2 . ILE B 1 256 ? 131.385 141.594 118.359 1.00 53.43  ? 256 ILE A CG2 1 
ATOM   5407 C  CD1 . ILE B 1 256 ? 133.550 142.678 116.669 1.00 53.43  ? 256 ILE A CD1 1 
ATOM   5408 N  N   . THR B 1 257 ? 132.080 141.927 122.074 1.00 54.48  ? 257 THR A N   1 
ATOM   5409 C  CA  . THR B 1 257 ? 131.623 140.995 123.095 1.00 54.48  ? 257 THR A CA  1 
ATOM   5410 C  C   . THR B 1 257 ? 131.029 141.688 124.313 1.00 54.48  ? 257 THR A C   1 
ATOM   5411 O  O   . THR B 1 257 ? 130.634 141.004 125.263 1.00 54.48  ? 257 THR A O   1 
ATOM   5412 C  CB  . THR B 1 257 ? 132.775 140.091 123.534 1.00 54.48  ? 257 THR A CB  1 
ATOM   5413 O  OG1 . THR B 1 257 ? 133.773 140.878 124.194 1.00 54.48  ? 257 THR A OG1 1 
ATOM   5414 C  CG2 . THR B 1 257 ? 133.393 139.403 122.329 1.00 54.48  ? 257 THR A CG2 1 
ATOM   5415 N  N   . GLY B 1 258 ? 130.962 143.020 124.314 1.00 52.19  ? 258 GLY A N   1 
ATOM   5416 C  CA  . GLY B 1 258 ? 130.451 143.723 125.478 1.00 52.19  ? 258 GLY A CA  1 
ATOM   5417 C  C   . GLY B 1 258 ? 128.987 143.436 125.751 1.00 52.19  ? 258 GLY A C   1 
ATOM   5418 O  O   . GLY B 1 258 ? 128.590 143.236 126.901 1.00 52.19  ? 258 GLY A O   1 
ATOM   5419 N  N   . THR B 1 259 ? 128.168 143.406 124.704 1.00 53.74  ? 259 THR A N   1 
ATOM   5420 C  CA  . THR B 1 259 ? 126.727 143.265 124.845 1.00 53.74  ? 259 THR A CA  1 
ATOM   5421 C  C   . THR B 1 259 ? 126.223 142.197 123.884 1.00 53.74  ? 259 THR A C   1 
ATOM   5422 O  O   . THR B 1 259 ? 126.768 142.016 122.793 1.00 53.74  ? 259 THR A O   1 
ATOM   5423 C  CB  . THR B 1 259 ? 126.014 144.607 124.577 1.00 53.74  ? 259 THR A CB  1 
ATOM   5424 O  OG1 . THR B 1 259 ? 126.538 145.608 125.457 1.00 53.74  ? 259 THR A OG1 1 
ATOM   5425 C  CG2 . THR B 1 259 ? 124.516 144.493 124.811 1.00 53.74  ? 259 THR A CG2 1 
ATOM   5426 N  N   . SER B 1 260 ? 125.176 141.482 124.307 1.00 54.03  ? 260 SER A N   1 
ATOM   5427 C  CA  . SER B 1 260 ? 124.574 140.468 123.448 1.00 54.03  ? 260 SER A CA  1 
ATOM   5428 C  C   . SER B 1 260 ? 124.009 141.074 122.171 1.00 54.03  ? 260 SER A C   1 
ATOM   5429 O  O   . SER B 1 260 ? 123.925 140.389 121.145 1.00 54.03  ? 260 SER A O   1 
ATOM   5430 C  CB  . SER B 1 260 ? 123.479 139.720 124.207 1.00 54.03  ? 260 SER A CB  1 
ATOM   5431 O  OG  . SER B 1 260 ? 122.487 140.614 124.680 1.00 54.03  ? 260 SER A OG  1 
ATOM   5432 N  N   . THR B 1 261 ? 123.607 142.346 122.212 1.00 50.52  ? 261 THR A N   1 
ATOM   5433 C  CA  . THR B 1 261 ? 123.136 143.013 121.002 1.00 50.52  ? 261 THR A CA  1 
ATOM   5434 C  C   . THR B 1 261 ? 124.236 143.077 119.950 1.00 50.52  ? 261 THR A C   1 
ATOM   5435 O  O   . THR B 1 261 ? 123.988 142.839 118.760 1.00 50.52  ? 261 THR A O   1 
ATOM   5436 C  CB  . THR B 1 261 ? 122.637 144.417 121.340 1.00 50.52  ? 261 THR A CB  1 
ATOM   5437 O  OG1 . THR B 1 261 ? 121.595 144.332 122.320 1.00 50.52  ? 261 THR A OG1 1 
ATOM   5438 C  CG2 . THR B 1 261 ? 122.104 145.108 120.102 1.00 50.52  ? 261 THR A CG2 1 
ATOM   5439 N  N   . ASN B 1 262 ? 125.459 143.396 120.372 1.00 51.90  ? 262 ASN A N   1 
ATOM   5440 C  CA  . ASN B 1 262 ? 126.579 143.412 119.440 1.00 51.90  ? 262 ASN A CA  1 
ATOM   5441 C  C   . ASN B 1 262 ? 126.870 142.015 118.908 1.00 51.90  ? 262 ASN A C   1 
ATOM   5442 O  O   . ASN B 1 262 ? 127.228 141.857 117.737 1.00 51.90  ? 262 ASN A O   1 
ATOM   5443 C  CB  . ASN B 1 262 ? 127.811 144.008 120.114 1.00 51.90  ? 262 ASN A CB  1 
ATOM   5444 C  CG  . ASN B 1 262 ? 127.596 145.438 120.557 1.00 51.90  ? 262 ASN A CG  1 
ATOM   5445 O  OD1 . ASN B 1 262 ? 126.729 146.137 120.036 1.00 51.90  ? 262 ASN A OD1 1 
ATOM   5446 N  ND2 . ASN B 1 262 ? 128.384 145.881 121.526 1.00 51.90  ? 262 ASN A ND2 1 
ATOM   5447 N  N   . LEU B 1 263 ? 126.716 140.988 119.750 1.00 55.20  ? 263 LEU A N   1 
ATOM   5448 C  CA  . LEU B 1 263 ? 126.866 139.615 119.273 1.00 55.20  ? 263 LEU A CA  1 
ATOM   5449 C  C   . LEU B 1 263 ? 125.845 139.290 118.192 1.00 55.20  ? 263 LEU A C   1 
ATOM   5450 O  O   . LEU B 1 263 ? 126.187 138.696 117.162 1.00 55.20  ? 263 LEU A O   1 
ATOM   5451 C  CB  . LEU B 1 263 ? 126.727 138.630 120.434 1.00 55.20  ? 263 LEU A CB  1 
ATOM   5452 C  CG  . LEU B 1 263 ? 127.991 138.111 121.119 1.00 55.20  ? 263 LEU A CG  1 
ATOM   5453 C  CD1 . LEU B 1 263 ? 128.908 139.247 121.500 1.00 55.20  ? 263 LEU A CD1 1 
ATOM   5454 C  CD2 . LEU B 1 263 ? 127.623 137.295 122.342 1.00 55.20  ? 263 LEU A CD2 1 
ATOM   5455 N  N   . ILE B 1 264 ? 124.585 139.670 118.410 1.00 52.29  ? 264 ILE A N   1 
ATOM   5456 C  CA  . ILE B 1 264 ? 123.544 139.392 117.427 1.00 52.29  ? 264 ILE A CA  1 
ATOM   5457 C  C   . ILE B 1 264 ? 123.839 140.115 116.122 1.00 52.29  ? 264 ILE A C   1 
ATOM   5458 O  O   . ILE B 1 264 ? 123.732 139.533 115.034 1.00 52.29  ? 264 ILE A O   1 
ATOM   5459 C  CB  . ILE B 1 264 ? 122.162 139.779 117.984 1.00 52.29  ? 264 ILE A CB  1 
ATOM   5460 C  CG1 . ILE B 1 264 ? 121.810 138.900 119.180 1.00 52.29  ? 264 ILE A CG1 1 
ATOM   5461 C  CG2 . ILE B 1 264 ? 121.103 139.656 116.907 1.00 52.29  ? 264 ILE A CG2 1 
ATOM   5462 C  CD1 . ILE B 1 264 ? 120.509 139.259 119.834 1.00 52.29  ? 264 ILE A CD1 1 
ATOM   5463 N  N   . PHE B 1 265 ? 124.219 141.392 116.206 1.00 54.35  ? 265 PHE A N   1 
ATOM   5464 C  CA  . PHE B 1 265 ? 124.522 142.138 114.990 1.00 54.35  ? 265 PHE A CA  1 
ATOM   5465 C  C   . PHE B 1 265 ? 125.706 141.531 114.252 1.00 54.35  ? 265 PHE A C   1 
ATOM   5466 O  O   . PHE B 1 265 ? 125.675 141.396 113.024 1.00 54.35  ? 265 PHE A O   1 
ATOM   5467 C  CB  . PHE B 1 265 ? 124.803 143.603 115.309 1.00 54.35  ? 265 PHE A CB  1 
ATOM   5468 C  CG  . PHE B 1 265 ? 125.426 144.354 114.169 1.00 54.35  ? 265 PHE A CG  1 
ATOM   5469 C  CD1 . PHE B 1 265 ? 124.747 144.509 112.975 1.00 54.35  ? 265 PHE A CD1 1 
ATOM   5470 C  CD2 . PHE B 1 265 ? 126.695 144.888 114.281 1.00 54.35  ? 265 PHE A CD2 1 
ATOM   5471 C  CE1 . PHE B 1 265 ? 125.316 145.194 111.921 1.00 54.35  ? 265 PHE A CE1 1 
ATOM   5472 C  CE2 . PHE B 1 265 ? 127.269 145.573 113.228 1.00 54.35  ? 265 PHE A CE2 1 
ATOM   5473 C  CZ  . PHE B 1 265 ? 126.578 145.725 112.049 1.00 54.35  ? 265 PHE A CZ  1 
ATOM   5474 N  N   . ALA B 1 266 ? 126.757 141.155 114.983 1.00 59.83  ? 266 ALA A N   1 
ATOM   5475 C  CA  . ALA B 1 266 ? 127.937 140.581 114.347 1.00 59.83  ? 266 ALA A CA  1 
ATOM   5476 C  C   . ALA B 1 266 ? 127.602 139.266 113.657 1.00 59.83  ? 266 ALA A C   1 
ATOM   5477 O  O   . ALA B 1 266 ? 128.010 139.031 112.515 1.00 59.83  ? 266 ALA A O   1 
ATOM   5478 C  CB  . ALA B 1 266 ? 129.044 140.384 115.381 1.00 59.83  ? 266 ALA A CB  1 
ATOM   5479 N  N   . GLU B 1 267 ? 126.848 138.398 114.334 1.00 62.48  ? 267 GLU A N   1 
ATOM   5480 C  CA  . GLU B 1 267 ? 126.494 137.112 113.743 1.00 62.48  ? 267 GLU A CA  1 
ATOM   5481 C  C   . GLU B 1 267 ? 125.623 137.297 112.508 1.00 62.48  ? 267 GLU A C   1 
ATOM   5482 O  O   . GLU B 1 267 ? 125.853 136.662 111.471 1.00 62.48  ? 267 GLU A O   1 
ATOM   5483 C  CB  . GLU B 1 267 ? 125.785 136.239 114.776 1.00 62.48  ? 267 GLU A CB  1 
ATOM   5484 C  CG  . GLU B 1 267 ? 126.690 135.227 115.447 1.00 62.48  ? 267 GLU A CG  1 
ATOM   5485 C  CD  . GLU B 1 267 ? 126.151 134.766 116.784 1.00 62.48  ? 267 GLU A CD  1 
ATOM   5486 O  OE1 . GLU B 1 267 ? 124.925 134.874 117.000 1.00 62.48  ? 267 GLU A OE1 1 
ATOM   5487 O  OE2 . GLU B 1 267 ? 126.952 134.297 117.620 1.00 62.48  ? 267 GLU A OE2 1 
ATOM   5488 N  N   . TYR B 1 268 ? 124.617 138.171 112.597 1.00 59.94  ? 268 TYR A N   1 
ATOM   5489 C  CA  . TYR B 1 268 ? 123.739 138.399 111.456 1.00 59.94  ? 268 TYR A CA  1 
ATOM   5490 C  C   . TYR B 1 268 ? 124.507 138.981 110.278 1.00 59.94  ? 268 TYR A C   1 
ATOM   5491 O  O   . TYR B 1 268 ? 124.290 138.580 109.129 1.00 59.94  ? 268 TYR A O   1 
ATOM   5492 C  CB  . TYR B 1 268 ? 122.589 139.320 111.853 1.00 59.94  ? 268 TYR A CB  1 
ATOM   5493 C  CG  . TYR B 1 268 ? 121.617 139.618 110.733 1.00 59.94  ? 268 TYR A CG  1 
ATOM   5494 C  CD1 . TYR B 1 268 ? 121.823 140.690 109.876 1.00 59.94  ? 268 TYR A CD1 1 
ATOM   5495 C  CD2 . TYR B 1 268 ? 120.487 138.837 110.542 1.00 59.94  ? 268 TYR A CD2 1 
ATOM   5496 C  CE1 . TYR B 1 268 ? 120.942 140.966 108.854 1.00 59.94  ? 268 TYR A CE1 1 
ATOM   5497 C  CE2 . TYR B 1 268 ? 119.597 139.107 109.523 1.00 59.94  ? 268 TYR A CE2 1 
ATOM   5498 C  CZ  . TYR B 1 268 ? 119.829 140.174 108.682 1.00 59.94  ? 268 TYR A CZ  1 
ATOM   5499 O  OH  . TYR B 1 268 ? 118.947 140.451 107.664 1.00 59.94  ? 268 TYR A OH  1 
ATOM   5500 N  N   . PHE B 1 269 ? 125.406 139.932 110.539 1.00 63.95  ? 269 PHE A N   1 
ATOM   5501 C  CA  . PHE B 1 269 ? 126.159 140.540 109.451 1.00 63.95  ? 269 PHE A CA  1 
ATOM   5502 C  C   . PHE B 1 269 ? 127.135 139.550 108.831 1.00 63.95  ? 269 PHE A C   1 
ATOM   5503 O  O   . PHE B 1 269 ? 127.353 139.567 107.614 1.00 63.95  ? 269 PHE A O   1 
ATOM   5504 C  CB  . PHE B 1 269 ? 126.895 141.779 109.949 1.00 63.95  ? 269 PHE A CB  1 
ATOM   5505 C  CG  . PHE B 1 269 ? 127.620 142.517 108.869 1.00 63.95  ? 269 PHE A CG  1 
ATOM   5506 C  CD1 . PHE B 1 269 ? 126.922 143.251 107.932 1.00 63.95  ? 269 PHE A CD1 1 
ATOM   5507 C  CD2 . PHE B 1 269 ? 129.000 142.475 108.790 1.00 63.95  ? 269 PHE A CD2 1 
ATOM   5508 C  CE1 . PHE B 1 269 ? 127.585 143.926 106.933 1.00 63.95  ? 269 PHE A CE1 1 
ATOM   5509 C  CE2 . PHE B 1 269 ? 129.669 143.154 107.795 1.00 63.95  ? 269 PHE A CE2 1 
ATOM   5510 C  CZ  . PHE B 1 269 ? 128.961 143.882 106.867 1.00 63.95  ? 269 PHE A CZ  1 
ATOM   5511 N  N   . ASN B 1 270 ? 127.740 138.685 109.648 1.00 65.17  ? 270 ASN A N   1 
ATOM   5512 C  CA  . ASN B 1 270 ? 128.650 137.683 109.108 1.00 65.17  ? 270 ASN A CA  1 
ATOM   5513 C  C   . ASN B 1 270 ? 127.906 136.661 108.258 1.00 65.17  ? 270 ASN A C   1 
ATOM   5514 O  O   . ASN B 1 270 ? 128.407 136.237 107.210 1.00 65.17  ? 270 ASN A O   1 
ATOM   5515 C  CB  . ASN B 1 270 ? 129.405 136.996 110.244 1.00 65.17  ? 270 ASN A CB  1 
ATOM   5516 C  CG  . ASN B 1 270 ? 130.629 137.774 110.680 1.00 65.17  ? 270 ASN A CG  1 
ATOM   5517 O  OD1 . ASN B 1 270 ? 130.752 138.967 110.404 1.00 65.17  ? 270 ASN A OD1 1 
ATOM   5518 N  ND2 . ASN B 1 270 ? 131.543 137.101 111.368 1.00 65.17  ? 270 ASN A ND2 1 
ATOM   5519 N  N   . THR B 1 271 ? 126.711 136.250 108.690 1.00 67.37  ? 271 THR A N   1 
ATOM   5520 C  CA  . THR B 1 271 ? 125.955 135.275 107.910 1.00 67.37  ? 271 THR A CA  1 
ATOM   5521 C  C   . THR B 1 271 ? 125.406 135.885 106.626 1.00 67.37  ? 271 THR A C   1 
ATOM   5522 O  O   . THR B 1 271 ? 125.521 135.286 105.551 1.00 67.37  ? 271 THR A O   1 
ATOM   5523 C  CB  . THR B 1 271 ? 124.815 134.692 108.744 1.00 67.37  ? 271 THR A CB  1 
ATOM   5524 O  OG1 . THR B 1 271 ? 123.974 135.754 109.210 1.00 67.37  ? 271 THR A OG1 1 
ATOM   5525 C  CG2 . THR B 1 271 ? 125.361 133.913 109.930 1.00 67.37  ? 271 THR A CG2 1 
ATOM   5526 N  N   . ARG B 1 272 ? 124.807 137.076 106.713 1.00 66.09  ? 272 ARG A N   1 
ATOM   5527 C  CA  . ARG B 1 272 ? 124.115 137.635 105.556 1.00 66.09  ? 272 ARG A CA  1 
ATOM   5528 C  C   . ARG B 1 272 ? 125.086 138.183 104.517 1.00 66.09  ? 272 ARG A C   1 
ATOM   5529 O  O   . ARG B 1 272 ? 124.775 138.177 103.321 1.00 66.09  ? 272 ARG A O   1 
ATOM   5530 C  CB  . ARG B 1 272 ? 123.138 138.720 106.003 1.00 66.09  ? 272 ARG A CB  1 
ATOM   5531 C  CG  . ARG B 1 272 ? 122.108 139.091 104.949 1.00 66.09  ? 272 ARG A CG  1 
ATOM   5532 C  CD  . ARG B 1 272 ? 121.683 140.546 105.069 1.00 66.09  ? 272 ARG A CD  1 
ATOM   5533 N  NE  . ARG B 1 272 ? 120.688 140.931 104.074 1.00 66.09  ? 272 ARG A NE  1 
ATOM   5534 C  CZ  . ARG B 1 272 ? 119.462 140.430 103.990 1.00 66.09  ? 272 ARG A CZ  1 
ATOM   5535 N  NH1 . ARG B 1 272 ? 119.014 139.542 104.864 1.00 66.09  ? 272 ARG A NH1 1 
ATOM   5536 N  NH2 . ARG B 1 272 ? 118.660 140.839 103.012 1.00 66.09  ? 272 ARG A NH2 1 
ATOM   5537 N  N   . TYR B 1 273 ? 126.255 138.657 104.942 1.00 67.65  ? 273 TYR A N   1 
ATOM   5538 C  CA  . TYR B 1 273 ? 127.288 139.152 104.032 1.00 67.65  ? 273 TYR A CA  1 
ATOM   5539 C  C   . TYR B 1 273 ? 128.602 138.445 104.334 1.00 67.65  ? 273 TYR A C   1 
ATOM   5540 O  O   . TYR B 1 273 ? 129.510 139.023 104.944 1.00 67.65  ? 273 TYR A O   1 
ATOM   5541 C  CB  . TYR B 1 273 ? 127.451 140.668 104.145 1.00 67.65  ? 273 TYR A CB  1 
ATOM   5542 C  CG  . TYR B 1 273 ? 126.174 141.454 103.975 1.00 67.65  ? 273 TYR A CG  1 
ATOM   5543 C  CD1 . TYR B 1 273 ? 125.636 141.676 102.716 1.00 67.65  ? 273 TYR A CD1 1 
ATOM   5544 C  CD2 . TYR B 1 273 ? 125.515 141.989 105.072 1.00 67.65  ? 273 TYR A CD2 1 
ATOM   5545 C  CE1 . TYR B 1 273 ? 124.472 142.401 102.556 1.00 67.65  ? 273 TYR A CE1 1 
ATOM   5546 C  CE2 . TYR B 1 273 ? 124.354 142.717 104.922 1.00 67.65  ? 273 TYR A CE2 1 
ATOM   5547 C  CZ  . TYR B 1 273 ? 123.836 142.918 103.662 1.00 67.65  ? 273 TYR A CZ  1 
ATOM   5548 O  OH  . TYR B 1 273 ? 122.676 143.640 103.508 1.00 67.65  ? 273 TYR A OH  1 
ATOM   5549 N  N   . PRO B 1 274 ? 128.735 137.181 103.923 1.00 74.05  ? 274 PRO A N   1 
ATOM   5550 C  CA  . PRO B 1 274 ? 130.005 136.472 104.149 1.00 74.05  ? 274 PRO A CA  1 
ATOM   5551 C  C   . PRO B 1 274 ? 131.189 137.125 103.463 1.00 74.05  ? 274 PRO A C   1 
ATOM   5552 O  O   . PRO B 1 274 ? 132.314 137.034 103.969 1.00 74.05  ? 274 PRO A O   1 
ATOM   5553 C  CB  . PRO B 1 274 ? 129.730 135.068 103.589 1.00 74.05  ? 274 PRO A CB  1 
ATOM   5554 C  CG  . PRO B 1 274 ? 128.238 134.964 103.490 1.00 74.05  ? 274 PRO A CG  1 
ATOM   5555 C  CD  . PRO B 1 274 ? 127.753 136.347 103.213 1.00 74.05  ? 274 PRO A CD  1 
ATOM   5556 N  N   . ASP B 1 275 ? 130.970 137.776 102.318 1.00 79.93  ? 275 ASP A N   1 
ATOM   5557 C  CA  . ASP B 1 275 ? 132.064 138.448 101.623 1.00 79.93  ? 275 ASP A CA  1 
ATOM   5558 C  C   . ASP B 1 275 ? 132.616 139.597 102.459 1.00 79.93  ? 275 ASP A C   1 
ATOM   5559 O  O   . ASP B 1 275 ? 133.833 139.813 102.505 1.00 79.93  ? 275 ASP A O   1 
ATOM   5560 C  CB  . ASP B 1 275 ? 131.579 138.941 100.257 1.00 79.93  ? 275 ASP A CB  1 
ATOM   5561 C  CG  . ASP B 1 275 ? 132.716 139.367 99.337  1.00 79.93  ? 275 ASP A CG  1 
ATOM   5562 O  OD1 . ASP B 1 275 ? 132.655 139.029 98.136  1.00 79.93  ? 275 ASP A OD1 1 
ATOM   5563 O  OD2 . ASP B 1 275 ? 133.660 140.045 99.794  1.00 79.93  ? 275 ASP A OD2 1 
ATOM   5564 N  N   . CYS B 1 276 ? 131.740 140.338 103.133 1.00 78.16  ? 276 CYS A N   1 
ATOM   5565 C  CA  . CYS B 1 276 ? 132.171 141.469 103.946 1.00 78.16  ? 276 CYS A CA  1 
ATOM   5566 C  C   . CYS B 1 276 ? 132.969 140.977 105.147 1.00 78.16  ? 276 CYS A C   1 
ATOM   5567 O  O   . CYS B 1 276 ? 132.475 140.171 105.942 1.00 78.16  ? 276 CYS A O   1 
ATOM   5568 C  CB  . CYS B 1 276 ? 130.962 142.278 104.406 1.00 78.16  ? 276 CYS A CB  1 
ATOM   5569 N  N   . ARG B 1 277 ? 134.203 141.466 105.279 1.00 80.51  ? 277 ARG A N   1 
ATOM   5570 C  CA  . ARG B 1 277 ? 135.070 141.095 106.390 1.00 80.51  ? 277 ARG A CA  1 
ATOM   5571 C  C   . ARG B 1 277 ? 135.614 142.309 107.132 1.00 80.51  ? 277 ARG A C   1 
ATOM   5572 O  O   . ARG B 1 277 ? 136.489 142.153 107.991 1.00 80.51  ? 277 ARG A O   1 
ATOM   5573 C  CB  . ARG B 1 277 ? 136.233 140.225 105.900 1.00 80.51  ? 277 ARG A CB  1 
ATOM   5574 C  CG  . ARG B 1 277 ? 135.819 139.112 104.953 1.00 80.51  ? 277 ARG A CG  1 
ATOM   5575 C  CD  . ARG B 1 277 ? 137.014 138.270 104.524 1.00 80.51  ? 277 ARG A CD  1 
ATOM   5576 N  NE  . ARG B 1 277 ? 136.634 136.960 104.003 1.00 80.51  ? 277 ARG A NE  1 
ATOM   5577 C  CZ  . ARG B 1 277 ? 135.978 136.027 104.682 1.00 80.51  ? 277 ARG A CZ  1 
ATOM   5578 N  NH1 . ARG B 1 277 ? 135.646 136.195 105.952 1.00 80.51  ? 277 ARG A NH1 1 
ATOM   5579 N  NH2 . ARG B 1 277 ? 135.661 134.887 104.075 1.00 80.51  ? 277 ARG A NH2 1 
ATOM   5580 N  N   . CYS B 1 278 ? 135.122 143.512 106.825 1.00 76.04  ? 278 CYS A N   1 
ATOM   5581 C  CA  . CYS B 1 278 ? 135.616 144.716 107.481 1.00 76.04  ? 278 CYS A CA  1 
ATOM   5582 C  C   . CYS B 1 278 ? 135.205 144.794 108.944 1.00 76.04  ? 278 CYS A C   1 
ATOM   5583 O  O   . CYS B 1 278 ? 135.774 145.598 109.691 1.00 76.04  ? 278 CYS A O   1 
ATOM   5584 C  CB  . CYS B 1 278 ? 135.123 145.958 106.739 1.00 76.04  ? 278 CYS A CB  1 
ATOM   5585 S  SG  . CYS B 1 278 ? 133.325 146.127 106.690 1.00 76.04  ? 278 CYS A SG  1 
ATOM   5586 N  N   . LEU B 1 279 ? 134.237 143.988 109.369 1.00 67.00  ? 279 LEU A N   1 
ATOM   5587 C  CA  . LEU B 1 279 ? 133.762 143.997 110.748 1.00 67.00  ? 279 LEU A CA  1 
ATOM   5588 C  C   . LEU B 1 279 ? 134.547 142.966 111.550 1.00 67.00  ? 279 LEU A C   1 
ATOM   5589 O  O   . LEU B 1 279 ? 134.425 141.760 111.314 1.00 67.00  ? 279 LEU A O   1 
ATOM   5590 C  CB  . LEU B 1 279 ? 132.265 143.708 110.802 1.00 67.00  ? 279 LEU A CB  1 
ATOM   5591 C  CG  . LEU B 1 279 ? 131.549 144.183 112.065 1.00 67.00  ? 279 LEU A CG  1 
ATOM   5592 C  CD1 . LEU B 1 279 ? 131.428 145.697 112.063 1.00 67.00  ? 279 LEU A CD1 1 
ATOM   5593 C  CD2 . LEU B 1 279 ? 130.184 143.528 112.187 1.00 67.00  ? 279 LEU A CD2 1 
ATOM   5594 N  N   . ASN B 1 280 ? 135.348 143.440 112.498 1.00 65.35  ? 280 ASN A N   1 
ATOM   5595 C  CA  . ASN B 1 280 ? 136.096 142.572 113.398 1.00 65.35  ? 280 ASN A CA  1 
ATOM   5596 C  C   . ASN B 1 280 ? 136.363 143.348 114.682 1.00 65.35  ? 280 ASN A C   1 
ATOM   5597 O  O   . ASN B 1 280 ? 135.882 144.472 114.857 1.00 65.35  ? 280 ASN A O   1 
ATOM   5598 C  CB  . ASN B 1 280 ? 137.384 142.069 112.737 1.00 65.35  ? 280 ASN A CB  1 
ATOM   5599 C  CG  . ASN B 1 280 ? 138.122 143.159 111.993 1.00 65.35  ? 280 ASN A CG  1 
ATOM   5600 O  OD1 . ASN B 1 280 ? 137.724 144.321 112.020 1.00 65.35  ? 280 ASN A OD1 1 
ATOM   5601 N  ND2 . ASN B 1 280 ? 139.206 142.789 111.321 1.00 65.35  ? 280 ASN A ND2 1 
ATOM   5602 N  N   . PHE B 1 281 ? 137.135 142.743 115.587 1.00 62.19  ? 281 PHE A N   1 
ATOM   5603 C  CA  . PHE B 1 281 ? 137.341 143.329 116.908 1.00 62.19  ? 281 PHE A CA  1 
ATOM   5604 C  C   . PHE B 1 281 ? 138.051 144.675 116.817 1.00 62.19  ? 281 PHE A C   1 
ATOM   5605 O  O   . PHE B 1 281 ? 137.612 145.666 117.417 1.00 62.19  ? 281 PHE A O   1 
ATOM   5606 C  CB  . PHE B 1 281 ? 138.136 142.358 117.781 1.00 62.19  ? 281 PHE A CB  1 
ATOM   5607 C  CG  . PHE B 1 281 ? 137.952 142.573 119.252 1.00 62.19  ? 281 PHE A CG  1 
ATOM   5608 C  CD1 . PHE B 1 281 ? 136.868 142.023 119.914 1.00 62.19  ? 281 PHE A CD1 1 
ATOM   5609 C  CD2 . PHE B 1 281 ? 138.867 143.316 119.976 1.00 62.19  ? 281 PHE A CD2 1 
ATOM   5610 C  CE1 . PHE B 1 281 ? 136.697 142.215 121.268 1.00 62.19  ? 281 PHE A CE1 1 
ATOM   5611 C  CE2 . PHE B 1 281 ? 138.702 143.512 121.332 1.00 62.19  ? 281 PHE A CE2 1 
ATOM   5612 C  CZ  . PHE B 1 281 ? 137.615 142.961 121.979 1.00 62.19  ? 281 PHE A CZ  1 
ATOM   5613 N  N   . GLY B 1 282 ? 139.152 144.730 116.064 1.00 61.09  ? 282 GLY A N   1 
ATOM   5614 C  CA  . GLY B 1 282 ? 139.936 145.953 116.007 1.00 61.09  ? 282 GLY A CA  1 
ATOM   5615 C  C   . GLY B 1 282 ? 139.177 147.108 115.385 1.00 61.09  ? 282 GLY A C   1 
ATOM   5616 O  O   . GLY B 1 282 ? 139.166 148.219 115.919 1.00 61.09  ? 282 GLY A O   1 
ATOM   5617 N  N   . SER B 1 283 ? 138.524 146.859 114.247 1.00 58.99  ? 283 SER A N   1 
ATOM   5618 C  CA  . SER B 1 283 ? 137.771 147.919 113.586 1.00 58.99  ? 283 SER A CA  1 
ATOM   5619 C  C   . SER B 1 283 ? 136.605 148.384 114.447 1.00 58.99  ? 283 SER A C   1 
ATOM   5620 O  O   . SER B 1 283 ? 136.321 149.588 114.528 1.00 58.99  ? 283 SER A O   1 
ATOM   5621 C  CB  . SER B 1 283 ? 137.276 147.442 112.223 1.00 58.99  ? 283 SER A CB  1 
ATOM   5622 O  OG  . SER B 1 283 ? 136.231 146.498 112.369 1.00 58.99  ? 283 SER A OG  1 
ATOM   5623 N  N   . TRP B 1 284 ? 135.916 147.442 115.095 1.00 55.85  ? 284 TRP A N   1 
ATOM   5624 C  CA  . TRP B 1 284 ? 134.803 147.808 115.961 1.00 55.85  ? 284 TRP A CA  1 
ATOM   5625 C  C   . TRP B 1 284 ? 135.271 148.701 117.100 1.00 55.85  ? 284 TRP A C   1 
ATOM   5626 O  O   . TRP B 1 284 ? 134.664 149.744 117.377 1.00 55.85  ? 284 TRP A O   1 
ATOM   5627 C  CB  . TRP B 1 284 ? 134.116 146.558 116.505 1.00 55.85  ? 284 TRP A CB  1 
ATOM   5628 C  CG  . TRP B 1 284 ? 132.889 146.868 117.300 1.00 55.85  ? 284 TRP A CG  1 
ATOM   5629 C  CD1 . TRP B 1 284 ? 132.834 147.222 118.615 1.00 55.85  ? 284 TRP A CD1 1 
ATOM   5630 C  CD2 . TRP B 1 284 ? 131.537 146.859 116.831 1.00 55.85  ? 284 TRP A CD2 1 
ATOM   5631 N  NE1 . TRP B 1 284 ? 131.533 147.433 118.996 1.00 55.85  ? 284 TRP A NE1 1 
ATOM   5632 C  CE2 . TRP B 1 284 ? 130.716 147.216 117.918 1.00 55.85  ? 284 TRP A CE2 1 
ATOM   5633 C  CE3 . TRP B 1 284 ? 130.940 146.582 115.599 1.00 55.85  ? 284 TRP A CE3 1 
ATOM   5634 C  CZ2 . TRP B 1 284 ? 129.331 147.303 117.810 1.00 55.85  ? 284 TRP A CZ2 1 
ATOM   5635 C  CZ3 . TRP B 1 284 ? 129.566 146.670 115.494 1.00 55.85  ? 284 TRP A CZ3 1 
ATOM   5636 C  CH2 . TRP B 1 284 ? 128.776 147.027 116.592 1.00 55.85  ? 284 TRP A CH2 1 
ATOM   5637 N  N   . PHE B 1 285 ? 136.361 148.314 117.767 1.00 57.16  ? 285 PHE A N   1 
ATOM   5638 C  CA  . PHE B 1 285 ? 136.878 149.151 118.843 1.00 57.16  ? 285 PHE A CA  1 
ATOM   5639 C  C   . PHE B 1 285 ? 137.296 150.518 118.321 1.00 57.16  ? 285 PHE A C   1 
ATOM   5640 O  O   . PHE B 1 285 ? 137.000 151.541 118.947 1.00 57.16  ? 285 PHE A O   1 
ATOM   5641 C  CB  . PHE B 1 285 ? 138.052 148.467 119.543 1.00 57.16  ? 285 PHE A CB  1 
ATOM   5642 C  CG  . PHE B 1 285 ? 138.613 149.260 120.691 1.00 57.16  ? 285 PHE A CG  1 
ATOM   5643 C  CD1 . PHE B 1 285 ? 138.091 149.122 121.964 1.00 57.16  ? 285 PHE A CD1 1 
ATOM   5644 C  CD2 . PHE B 1 285 ? 139.658 150.147 120.496 1.00 57.16  ? 285 PHE A CD2 1 
ATOM   5645 C  CE1 . PHE B 1 285 ? 138.602 149.851 123.019 1.00 57.16  ? 285 PHE A CE1 1 
ATOM   5646 C  CE2 . PHE B 1 285 ? 140.169 150.879 121.547 1.00 57.16  ? 285 PHE A CE2 1 
ATOM   5647 C  CZ  . PHE B 1 285 ? 139.640 150.730 122.809 1.00 57.16  ? 285 PHE A CZ  1 
ATOM   5648 N  N   . THR B 1 286 ? 137.970 150.559 117.169 1.00 59.16  ? 286 THR A N   1 
ATOM   5649 C  CA  . THR B 1 286 ? 138.460 151.835 116.659 1.00 59.16  ? 286 THR A CA  1 
ATOM   5650 C  C   . THR B 1 286 ? 137.314 152.788 116.345 1.00 59.16  ? 286 THR A C   1 
ATOM   5651 O  O   . THR B 1 286 ? 137.396 153.982 116.653 1.00 59.16  ? 286 THR A O   1 
ATOM   5652 C  CB  . THR B 1 286 ? 139.327 151.627 115.418 1.00 59.16  ? 286 THR A CB  1 
ATOM   5653 O  OG1 . THR B 1 286 ? 138.647 150.776 114.491 1.00 59.16  ? 286 THR A OG1 1 
ATOM   5654 C  CG2 . THR B 1 286 ? 140.663 151.007 115.795 1.00 59.16  ? 286 THR A CG2 1 
ATOM   5655 N  N   . PHE B 1 287 ? 136.236 152.291 115.736 1.00 56.82  ? 287 PHE A N   1 
ATOM   5656 C  CA  . PHE B 1 287 ? 135.165 153.215 115.385 1.00 56.82  ? 287 PHE A CA  1 
ATOM   5657 C  C   . PHE B 1 287 ? 134.180 153.446 116.523 1.00 56.82  ? 287 PHE A C   1 
ATOM   5658 O  O   . PHE B 1 287 ? 133.382 154.384 116.440 1.00 56.82  ? 287 PHE A O   1 
ATOM   5659 C  CB  . PHE B 1 287 ? 134.402 152.742 114.135 1.00 56.82  ? 287 PHE A CB  1 
ATOM   5660 C  CG  . PHE B 1 287 ? 133.211 151.865 114.420 1.00 56.82  ? 287 PHE A CG  1 
ATOM   5661 C  CD1 . PHE B 1 287 ? 133.338 150.494 114.482 1.00 56.82  ? 287 PHE A CD1 1 
ATOM   5662 C  CD2 . PHE B 1 287 ? 131.949 152.419 114.576 1.00 56.82  ? 287 PHE A CD2 1 
ATOM   5663 C  CE1 . PHE B 1 287 ? 132.238 149.694 114.727 1.00 56.82  ? 287 PHE A CE1 1 
ATOM   5664 C  CE2 . PHE B 1 287 ? 130.853 151.625 114.826 1.00 56.82  ? 287 PHE A CE2 1 
ATOM   5665 C  CZ  . PHE B 1 287 ? 130.997 150.261 114.900 1.00 56.82  ? 287 PHE A CZ  1 
ATOM   5666 N  N   . SER B 1 288 ? 134.217 152.638 117.585 1.00 52.29  ? 288 SER A N   1 
ATOM   5667 C  CA  . SER B 1 288 ? 133.270 152.818 118.676 1.00 52.29  ? 288 SER A CA  1 
ATOM   5668 C  C   . SER B 1 288 ? 133.860 153.504 119.900 1.00 52.29  ? 288 SER A C   1 
ATOM   5669 O  O   . SER B 1 288 ? 133.097 154.037 120.711 1.00 52.29  ? 288 SER A O   1 
ATOM   5670 C  CB  . SER B 1 288 ? 132.689 151.465 119.100 1.00 52.29  ? 288 SER A CB  1 
ATOM   5671 O  OG  . SER B 1 288 ? 131.752 151.625 120.148 1.00 52.29  ? 288 SER A OG  1 
ATOM   5672 N  N   . PHE B 1 289 ? 135.183 153.501 120.063 1.00 53.42  ? 289 PHE A N   1 
ATOM   5673 C  CA  . PHE B 1 289 ? 135.778 154.085 121.263 1.00 53.42  ? 289 PHE A CA  1 
ATOM   5674 C  C   . PHE B 1 289 ? 135.532 155.583 121.398 1.00 53.42  ? 289 PHE A C   1 
ATOM   5675 O  O   . PHE B 1 289 ? 135.144 156.017 122.496 1.00 53.42  ? 289 PHE A O   1 
ATOM   5676 C  CB  . PHE B 1 289 ? 137.276 153.766 121.302 1.00 53.42  ? 289 PHE A CB  1 
ATOM   5677 C  CG  . PHE B 1 289 ? 137.963 154.255 122.541 1.00 53.42  ? 289 PHE A CG  1 
ATOM   5678 C  CD1 . PHE B 1 289 ? 137.791 153.599 123.746 1.00 53.42  ? 289 PHE A CD1 1 
ATOM   5679 C  CD2 . PHE B 1 289 ? 138.777 155.372 122.502 1.00 53.42  ? 289 PHE A CD2 1 
ATOM   5680 C  CE1 . PHE B 1 289 ? 138.422 154.046 124.888 1.00 53.42  ? 289 PHE A CE1 1 
ATOM   5681 C  CE2 . PHE B 1 289 ? 139.410 155.824 123.640 1.00 53.42  ? 289 PHE A CE2 1 
ATOM   5682 C  CZ  . PHE B 1 289 ? 139.232 155.160 124.835 1.00 53.42  ? 289 PHE A CZ  1 
ATOM   5683 N  N   . PRO B 1 290 ? 135.761 156.425 120.380 1.00 51.86  ? 290 PRO A N   1 
ATOM   5684 C  CA  . PRO B 1 290 ? 135.519 157.866 120.583 1.00 51.86  ? 290 PRO A CA  1 
ATOM   5685 C  C   . PRO B 1 290 ? 134.085 158.192 120.957 1.00 51.86  ? 290 PRO A C   1 
ATOM   5686 O  O   . PRO B 1 290 ? 133.851 159.044 121.827 1.00 51.86  ? 290 PRO A O   1 
ATOM   5687 C  CB  . PRO B 1 290 ? 135.908 158.479 119.230 1.00 51.86  ? 290 PRO A CB  1 
ATOM   5688 C  CG  . PRO B 1 290 ? 136.823 157.489 118.613 1.00 51.86  ? 290 PRO A CG  1 
ATOM   5689 C  CD  . PRO B 1 290 ? 136.303 156.156 119.036 1.00 51.86  ? 290 PRO A CD  1 
ATOM   5690 N  N   . ALA B 1 291 ? 133.115 157.526 120.328 1.00 52.64  ? 291 ALA A N   1 
ATOM   5691 C  CA  . ALA B 1 291 ? 131.716 157.772 120.656 1.00 52.64  ? 291 ALA A CA  1 
ATOM   5692 C  C   . ALA B 1 291 ? 131.420 157.385 122.097 1.00 52.64  ? 291 ALA A C   1 
ATOM   5693 O  O   . ALA B 1 291 ? 130.763 158.132 122.832 1.00 52.64  ? 291 ALA A O   1 
ATOM   5694 C  CB  . ALA B 1 291 ? 130.809 157.006 119.693 1.00 52.64  ? 291 ALA A CB  1 
ATOM   5695 N  N   . ALA B 1 292 ? 131.913 156.221 122.524 1.00 49.81  ? 292 ALA A N   1 
ATOM   5696 C  CA  . ALA B 1 292 ? 131.688 155.782 123.896 1.00 49.81  ? 292 ALA A CA  1 
ATOM   5697 C  C   . ALA B 1 292 ? 132.337 156.733 124.892 1.00 49.81  ? 292 ALA A C   1 
ATOM   5698 O  O   . ALA B 1 292 ? 131.747 157.049 125.929 1.00 49.81  ? 292 ALA A O   1 
ATOM   5699 C  CB  . ALA B 1 292 ? 132.215 154.362 124.089 1.00 49.81  ? 292 ALA A CB  1 
ATOM   5700 N  N   . LEU B 1 293 ? 133.548 157.205 124.593 1.00 48.72  ? 293 LEU A N   1 
ATOM   5701 C  CA  . LEU B 1 293 ? 134.239 158.114 125.503 1.00 48.72  ? 293 LEU A CA  1 
ATOM   5702 C  C   . LEU B 1 293 ? 133.506 159.445 125.624 1.00 48.72  ? 293 LEU A C   1 
ATOM   5703 O  O   . LEU B 1 293 ? 133.332 159.974 126.731 1.00 48.72  ? 293 LEU A O   1 
ATOM   5704 C  CB  . LEU B 1 293 ? 135.674 158.333 125.029 1.00 48.72  ? 293 LEU A CB  1 
ATOM   5705 C  CG  . LEU B 1 293 ? 136.564 159.157 125.958 1.00 48.72  ? 293 LEU A CG  1 
ATOM   5706 C  CD1 . LEU B 1 293 ? 136.869 158.380 127.228 1.00 48.72  ? 293 LEU A CD1 1 
ATOM   5707 C  CD2 . LEU B 1 293 ? 137.845 159.561 125.249 1.00 48.72  ? 293 LEU A CD2 1 
ATOM   5708 N  N   . ILE B 1 294 ? 133.074 160.008 124.492 1.00 49.19  ? 294 ILE A N   1 
ATOM   5709 C  CA  . ILE B 1 294 ? 132.349 161.275 124.533 1.00 49.19  ? 294 ILE A CA  1 
ATOM   5710 C  C   . ILE B 1 294 ? 131.034 161.110 125.281 1.00 49.19  ? 294 ILE A C   1 
ATOM   5711 O  O   . ILE B 1 294 ? 130.659 161.957 126.104 1.00 49.19  ? 294 ILE A O   1 
ATOM   5712 C  CB  . ILE B 1 294 ? 132.129 161.817 123.110 1.00 49.19  ? 294 ILE A CB  1 
ATOM   5713 C  CG1 . ILE B 1 294 ? 133.461 162.219 122.480 1.00 49.19  ? 294 ILE A CG1 1 
ATOM   5714 C  CG2 . ILE B 1 294 ? 131.191 163.006 123.135 1.00 49.19  ? 294 ILE A CG2 1 
ATOM   5715 C  CD1 . ILE B 1 294 ? 133.353 162.587 121.018 1.00 49.19  ? 294 ILE A CD1 1 
ATOM   5716 N  N   . ILE B 1 295 ? 130.312 160.018 125.011 1.00 49.02  ? 295 ILE A N   1 
ATOM   5717 C  CA  . ILE B 1 295 ? 129.058 159.768 125.712 1.00 49.02  ? 295 ILE A CA  1 
ATOM   5718 C  C   . ILE B 1 295 ? 129.305 159.623 127.205 1.00 49.02  ? 295 ILE A C   1 
ATOM   5719 O  O   . ILE B 1 295 ? 128.537 160.135 128.023 1.00 49.02  ? 295 ILE A O   1 
ATOM   5720 C  CB  . ILE B 1 295 ? 128.354 158.529 125.130 1.00 49.02  ? 295 ILE A CB  1 
ATOM   5721 C  CG1 . ILE B 1 295 ? 127.821 158.826 123.731 1.00 49.02  ? 295 ILE A CG1 1 
ATOM   5722 C  CG2 . ILE B 1 295 ? 127.214 158.089 126.030 1.00 49.02  ? 295 ILE A CG2 1 
ATOM   5723 C  CD1 . ILE B 1 295 ? 127.277 157.611 123.022 1.00 49.02  ? 295 ILE A CD1 1 
ATOM   5724 N  N   . LEU B 1 296 ? 130.382 158.934 127.585 1.00 48.31  ? 296 LEU A N   1 
ATOM   5725 C  CA  . LEU B 1 296 ? 130.686 158.745 128.999 1.00 48.31  ? 296 LEU A CA  1 
ATOM   5726 C  C   . LEU B 1 296 ? 130.962 160.075 129.685 1.00 48.31  ? 296 LEU A C   1 
ATOM   5727 O  O   . LEU B 1 296 ? 130.434 160.347 130.768 1.00 48.31  ? 296 LEU A O   1 
ATOM   5728 C  CB  . LEU B 1 296 ? 131.879 157.803 129.153 1.00 48.31  ? 296 LEU A CB  1 
ATOM   5729 C  CG  . LEU B 1 296 ? 132.069 157.164 130.526 1.00 48.31  ? 296 LEU A CG  1 
ATOM   5730 C  CD1 . LEU B 1 296 ? 130.898 156.262 130.848 1.00 48.31  ? 296 LEU A CD1 1 
ATOM   5731 C  CD2 . LEU B 1 296 ? 133.370 156.387 130.571 1.00 48.31  ? 296 LEU A CD2 1 
ATOM   5732 N  N   . LEU B 1 297 ? 131.786 160.921 129.066 1.00 50.54  ? 297 LEU A N   1 
ATOM   5733 C  CA  . LEU B 1 297 ? 132.110 162.205 129.682 1.00 50.54  ? 297 LEU A CA  1 
ATOM   5734 C  C   . LEU B 1 297 ? 130.872 163.086 129.801 1.00 50.54  ? 297 LEU A C   1 
ATOM   5735 O  O   . LEU B 1 297 ? 130.609 163.675 130.860 1.00 50.54  ? 297 LEU A O   1 
ATOM   5736 C  CB  . LEU B 1 297 ? 133.203 162.914 128.885 1.00 50.54  ? 297 LEU A CB  1 
ATOM   5737 C  CG  . LEU B 1 297 ? 134.623 162.378 129.065 1.00 50.54  ? 297 LEU A CG  1 
ATOM   5738 C  CD1 . LEU B 1 297 ? 135.640 163.362 128.512 1.00 50.54  ? 297 LEU A CD1 1 
ATOM   5739 C  CD2 . LEU B 1 297 ? 134.905 162.080 130.527 1.00 50.54  ? 297 LEU A CD2 1 
ATOM   5740 N  N   . LEU B 1 298 ? 130.088 163.181 128.723 1.00 51.26  ? 298 LEU A N   1 
ATOM   5741 C  CA  . LEU B 1 298 ? 128.892 164.016 128.763 1.00 51.26  ? 298 LEU A CA  1 
ATOM   5742 C  C   . LEU B 1 298 ? 127.869 163.476 129.754 1.00 51.26  ? 298 LEU A C   1 
ATOM   5743 O  O   . LEU B 1 298 ? 127.207 164.252 130.450 1.00 51.26  ? 298 LEU A O   1 
ATOM   5744 C  CB  . LEU B 1 298 ? 128.282 164.139 127.367 1.00 51.26  ? 298 LEU A CB  1 
ATOM   5745 C  CG  . LEU B 1 298 ? 128.805 165.252 126.454 1.00 51.26  ? 298 LEU A CG  1 
ATOM   5746 C  CD1 . LEU B 1 298 ? 128.490 166.610 127.057 1.00 51.26  ? 298 LEU A CD1 1 
ATOM   5747 C  CD2 . LEU B 1 298 ? 130.292 165.124 126.175 1.00 51.26  ? 298 LEU A CD2 1 
ATOM   5748 N  N   . SER B 1 299 ? 127.722 162.152 129.836 1.00 52.58  ? 299 SER A N   1 
ATOM   5749 C  CA  . SER B 1 299 ? 126.790 161.564 130.788 1.00 52.58  ? 299 SER A CA  1 
ATOM   5750 C  C   . SER B 1 299 ? 127.236 161.813 132.220 1.00 52.58  ? 299 SER A C   1 
ATOM   5751 O  O   . SER B 1 299 ? 126.404 162.081 133.092 1.00 52.58  ? 299 SER A O   1 
ATOM   5752 C  CB  . SER B 1 299 ? 126.647 160.068 130.524 1.00 52.58  ? 299 SER A CB  1 
ATOM   5753 O  OG  . SER B 1 299 ? 126.016 159.832 129.280 1.00 52.58  ? 299 SER A OG  1 
ATOM   5754 N  N   . TRP B 1 300 ? 128.540 161.723 132.486 1.00 54.73  ? 300 TRP A N   1 
ATOM   5755 C  CA  . TRP B 1 300 ? 129.035 162.038 133.821 1.00 54.73  ? 300 TRP A CA  1 
ATOM   5756 C  C   . TRP B 1 300 ? 128.735 163.485 134.178 1.00 54.73  ? 300 TRP A C   1 
ATOM   5757 O  O   . TRP B 1 300 ? 128.266 163.780 135.283 1.00 54.73  ? 300 TRP A O   1 
ATOM   5758 C  CB  . TRP B 1 300 ? 130.535 161.771 133.909 1.00 54.73  ? 300 TRP A CB  1 
ATOM   5759 C  CG  . TRP B 1 300 ? 131.166 162.408 135.103 1.00 54.73  ? 300 TRP A CG  1 
ATOM   5760 C  CD1 . TRP B 1 300 ? 130.924 162.110 136.410 1.00 54.73  ? 300 TRP A CD1 1 
ATOM   5761 C  CD2 . TRP B 1 300 ? 132.138 163.459 135.104 1.00 54.73  ? 300 TRP A CD2 1 
ATOM   5762 N  NE1 . TRP B 1 300 ? 131.687 162.906 137.226 1.00 54.73  ? 300 TRP A NE1 1 
ATOM   5763 C  CE2 . TRP B 1 300 ? 132.442 163.743 136.448 1.00 54.73  ? 300 TRP A CE2 1 
ATOM   5764 C  CE3 . TRP B 1 300 ? 132.782 164.185 134.099 1.00 54.73  ? 300 TRP A CE3 1 
ATOM   5765 C  CZ2 . TRP B 1 300 ? 133.361 164.723 136.814 1.00 54.73  ? 300 TRP A CZ2 1 
ATOM   5766 C  CZ3 . TRP B 1 300 ? 133.693 165.156 134.464 1.00 54.73  ? 300 TRP A CZ3 1 
ATOM   5767 C  CH2 . TRP B 1 300 ? 133.974 165.416 135.809 1.00 54.73  ? 300 TRP A CH2 1 
ATOM   5768 N  N   . ILE B 1 301 ? 128.985 164.403 133.241 1.00 53.24  ? 301 ILE A N   1 
ATOM   5769 C  CA  . ILE B 1 301 ? 128.721 165.816 133.502 1.00 53.24  ? 301 ILE A CA  1 
ATOM   5770 C  C   . ILE B 1 301 ? 127.236 166.038 133.767 1.00 53.24  ? 301 ILE A C   1 
ATOM   5771 O  O   . ILE B 1 301 ? 126.851 166.746 134.706 1.00 53.24  ? 301 ILE A O   1 
ATOM   5772 C  CB  . ILE B 1 301 ? 129.221 166.680 132.331 1.00 53.24  ? 301 ILE A CB  1 
ATOM   5773 C  CG1 . ILE B 1 301 ? 130.749 166.677 132.285 1.00 53.24  ? 301 ILE A CG1 1 
ATOM   5774 C  CG2 . ILE B 1 301 ? 128.697 168.099 132.454 1.00 53.24  ? 301 ILE A CG2 1 
ATOM   5775 C  CD1 . ILE B 1 301 ? 131.325 167.527 131.179 1.00 53.24  ? 301 ILE A CD1 1 
ATOM   5776 N  N   . TRP B 1 302 ? 126.381 165.427 132.946 1.00 53.16  ? 302 TRP A N   1 
ATOM   5777 C  CA  . TRP B 1 302 ? 124.941 165.617 133.081 1.00 53.16  ? 302 TRP A CA  1 
ATOM   5778 C  C   . TRP B 1 302 ? 124.426 165.050 134.398 1.00 53.16  ? 302 TRP A C   1 
ATOM   5779 O  O   . TRP B 1 302 ? 123.616 165.684 135.082 1.00 53.16  ? 302 TRP A O   1 
ATOM   5780 C  CB  . TRP B 1 302 ? 124.224 164.973 131.896 1.00 53.16  ? 302 TRP A CB  1 
ATOM   5781 C  CG  . TRP B 1 302 ? 122.771 164.746 132.122 1.00 53.16  ? 302 TRP A CG  1 
ATOM   5782 C  CD1 . TRP B 1 302 ? 122.152 163.550 132.319 1.00 53.16  ? 302 TRP A CD1 1 
ATOM   5783 C  CD2 . TRP B 1 302 ? 121.747 165.743 132.172 1.00 53.16  ? 302 TRP A CD2 1 
ATOM   5784 N  NE1 . TRP B 1 302 ? 120.803 163.738 132.489 1.00 53.16  ? 302 TRP A NE1 1 
ATOM   5785 C  CE2 . TRP B 1 302 ? 120.529 165.077 132.403 1.00 53.16  ? 302 TRP A CE2 1 
ATOM   5786 C  CE3 . TRP B 1 302 ? 121.742 167.134 132.044 1.00 53.16  ? 302 TRP A CE3 1 
ATOM   5787 C  CZ2 . TRP B 1 302 ? 119.319 165.755 132.509 1.00 53.16  ? 302 TRP A CZ2 1 
ATOM   5788 C  CZ3 . TRP B 1 302 ? 120.540 167.804 132.149 1.00 53.16  ? 302 TRP A CZ3 1 
ATOM   5789 C  CH2 . TRP B 1 302 ? 119.345 167.115 132.380 1.00 53.16  ? 302 TRP A CH2 1 
ATOM   5790 N  N   . LEU B 1 303 ? 124.883 163.852 134.769 1.00 54.75  ? 303 LEU A N   1 
ATOM   5791 C  CA  . LEU B 1 303 ? 124.448 163.253 136.026 1.00 54.75  ? 303 LEU A CA  1 
ATOM   5792 C  C   . LEU B 1 303 ? 124.934 164.065 137.218 1.00 54.75  ? 303 LEU A C   1 
ATOM   5793 O  O   . LEU B 1 303 ? 124.203 164.234 138.201 1.00 54.75  ? 303 LEU A O   1 
ATOM   5794 C  CB  . LEU B 1 303 ? 124.940 161.811 136.121 1.00 54.75  ? 303 LEU A CB  1 
ATOM   5795 C  CG  . LEU B 1 303 ? 124.229 160.796 135.227 1.00 54.75  ? 303 LEU A CG  1 
ATOM   5796 C  CD1 . LEU B 1 303 ? 124.831 159.416 135.407 1.00 54.75  ? 303 LEU A CD1 1 
ATOM   5797 C  CD2 . LEU B 1 303 ? 122.745 160.775 135.527 1.00 54.75  ? 303 LEU A CD2 1 
ATOM   5798 N  N   . GLN B 1 304 ? 126.168 164.572 137.153 1.00 62.97  ? 304 GLN A N   1 
ATOM   5799 C  CA  . GLN B 1 304 ? 126.673 165.409 138.235 1.00 62.97  ? 304 GLN A CA  1 
ATOM   5800 C  C   . GLN B 1 304 ? 125.859 166.689 138.365 1.00 62.97  ? 304 GLN A C   1 
ATOM   5801 O  O   . GLN B 1 304 ? 125.540 167.118 139.479 1.00 62.97  ? 304 GLN A O   1 
ATOM   5802 C  CB  . GLN B 1 304 ? 128.147 165.732 138.001 1.00 62.97  ? 304 GLN A CB  1 
ATOM   5803 C  CG  . GLN B 1 304 ? 128.904 166.093 139.260 1.00 62.97  ? 304 GLN A CG  1 
ATOM   5804 C  CD  . GLN B 1 304 ? 128.970 164.943 140.241 1.00 62.97  ? 304 GLN A CD  1 
ATOM   5805 O  OE1 . GLN B 1 304 ? 128.967 163.777 139.849 1.00 62.97  ? 304 GLN A OE1 1 
ATOM   5806 N  NE2 . GLN B 1 304 ? 129.027 165.266 141.528 1.00 62.97  ? 304 GLN A NE2 1 
ATOM   5807 N  N   . TRP B 1 305 ? 125.510 167.309 137.238 1.00 63.17  ? 305 TRP A N   1 
ATOM   5808 C  CA  . TRP B 1 305 ? 124.749 168.551 137.280 1.00 63.17  ? 305 TRP A CA  1 
ATOM   5809 C  C   . TRP B 1 305 ? 123.314 168.334 137.741 1.00 63.17  ? 305 TRP A C   1 
ATOM   5810 O  O   . TRP B 1 305 ? 122.752 169.196 138.425 1.00 63.17  ? 305 TRP A O   1 
ATOM   5811 C  CB  . TRP B 1 305 ? 124.760 169.218 135.905 1.00 63.17  ? 305 TRP A CB  1 
ATOM   5812 C  CG  . TRP B 1 305 ? 124.095 170.555 135.879 1.00 63.17  ? 305 TRP A CG  1 
ATOM   5813 C  CD1 . TRP B 1 305 ? 124.690 171.768 136.060 1.00 63.17  ? 305 TRP A CD1 1 
ATOM   5814 C  CD2 . TRP B 1 305 ? 122.705 170.819 135.657 1.00 63.17  ? 305 TRP A CD2 1 
ATOM   5815 N  NE1 . TRP B 1 305 ? 123.757 172.772 135.965 1.00 63.17  ? 305 TRP A NE1 1 
ATOM   5816 C  CE2 . TRP B 1 305 ? 122.531 172.215 135.718 1.00 63.17  ? 305 TRP A CE2 1 
ATOM   5817 C  CE3 . TRP B 1 305 ? 121.591 170.011 135.413 1.00 63.17  ? 305 TRP A CE3 1 
ATOM   5818 C  CZ2 . TRP B 1 305 ? 121.289 172.819 135.544 1.00 63.17  ? 305 TRP A CZ2 1 
ATOM   5819 C  CZ3 . TRP B 1 305 ? 120.360 170.613 135.241 1.00 63.17  ? 305 TRP A CZ3 1 
ATOM   5820 C  CH2 . TRP B 1 305 ? 120.218 172.003 135.308 1.00 63.17  ? 305 TRP A CH2 1 
ATOM   5821 N  N   . LEU B 1 306 ? 122.706 167.205 137.374 1.00 59.15  ? 306 LEU A N   1 
ATOM   5822 C  CA  . LEU B 1 306 ? 121.298 166.987 137.693 1.00 59.15  ? 306 LEU A CA  1 
ATOM   5823 C  C   . LEU B 1 306 ? 121.082 166.802 139.190 1.00 59.15  ? 306 LEU A C   1 
ATOM   5824 O  O   . LEU B 1 306 ? 120.155 167.385 139.764 1.00 59.15  ? 306 LEU A O   1 
ATOM   5825 C  CB  . LEU B 1 306 ? 120.771 165.777 136.924 1.00 59.15  ? 306 LEU A CB  1 
ATOM   5826 C  CG  . LEU B 1 306 ? 119.264 165.535 136.988 1.00 59.15  ? 306 LEU A CG  1 
ATOM   5827 C  CD1 . LEU B 1 306 ? 118.526 166.581 136.174 1.00 59.15  ? 306 LEU A CD1 1 
ATOM   5828 C  CD2 . LEU B 1 306 ? 118.927 164.138 136.499 1.00 59.15  ? 306 LEU A CD2 1 
ATOM   5829 N  N   . PHE B 1 307 ? 121.924 166.000 139.840 1.00 65.41  ? 307 PHE A N   1 
ATOM   5830 C  CA  . PHE B 1 307 ? 121.729 165.675 141.250 1.00 65.41  ? 307 PHE A CA  1 
ATOM   5831 C  C   . PHE B 1 307 ? 122.512 166.615 142.163 1.00 65.41  ? 307 PHE A C   1 
ATOM   5832 O  O   . PHE B 1 307 ? 121.928 167.296 143.011 1.00 65.41  ? 307 PHE A O   1 
ATOM   5833 C  CB  . PHE B 1 307 ? 122.120 164.216 141.507 1.00 65.41  ? 307 PHE A CB  1 
ATOM   5834 C  CG  . PHE B 1 307 ? 121.212 163.224 140.844 1.00 65.41  ? 307 PHE A CG  1 
ATOM   5835 C  CD1 . PHE B 1 307 ? 121.351 162.926 139.500 1.00 65.41  ? 307 PHE A CD1 1 
ATOM   5836 C  CD2 . PHE B 1 307 ? 120.210 162.598 141.563 1.00 65.41  ? 307 PHE A CD2 1 
ATOM   5837 C  CE1 . PHE B 1 307 ? 120.513 162.016 138.888 1.00 65.41  ? 307 PHE A CE1 1 
ATOM   5838 C  CE2 . PHE B 1 307 ? 119.370 161.687 140.957 1.00 65.41  ? 307 PHE A CE2 1 
ATOM   5839 C  CZ  . PHE B 1 307 ? 119.521 161.397 139.617 1.00 65.41  ? 307 PHE A CZ  1 
ATOM   5840 N  N   . LEU B 1 308 ? 123.829 166.656 142.005 1.00 68.88  ? 308 LEU A N   1 
ATOM   5841 C  CA  . LEU B 1 308 ? 124.663 167.570 142.768 1.00 68.88  ? 308 LEU A CA  1 
ATOM   5842 C  C   . LEU B 1 308 ? 124.865 168.856 141.970 1.00 68.88  ? 308 LEU A C   1 
ATOM   5843 O  O   . LEU B 1 308 ? 124.209 169.094 140.953 1.00 68.88  ? 308 LEU A O   1 
ATOM   5844 C  CB  . LEU B 1 308 ? 125.990 166.905 143.125 1.00 68.88  ? 308 LEU A CB  1 
ATOM   5845 C  CG  . LEU B 1 308 ? 126.041 166.140 144.448 1.00 68.88  ? 308 LEU A CG  1 
ATOM   5846 C  CD1 . LEU B 1 308 ? 125.323 164.809 144.331 1.00 68.88  ? 308 LEU A CD1 1 
ATOM   5847 C  CD2 . LEU B 1 308 ? 127.481 165.935 144.887 1.00 68.88  ? 308 LEU A CD2 1 
ATOM   5848 N  N   . GLY B 1 309 ? 125.774 169.705 142.429 1.00 81.50  ? 309 GLY A N   1 
ATOM   5849 C  CA  . GLY B 1 309 ? 126.150 170.917 141.717 1.00 81.50  ? 309 GLY A CA  1 
ATOM   5850 C  C   . GLY B 1 309 ? 127.552 170.770 141.154 1.00 81.50  ? 309 GLY A C   1 
ATOM   5851 O  O   . GLY B 1 309 ? 128.455 170.276 141.836 1.00 81.50  ? 309 GLY A O   1 
ATOM   5852 N  N   . PHE B 1 310 ? 127.728 171.199 139.907 1.00 89.85  ? 310 PHE A N   1 
ATOM   5853 C  CA  . PHE B 1 310 ? 129.020 171.098 139.234 1.00 89.85  ? 310 PHE A CA  1 
ATOM   5854 C  C   . PHE B 1 310 ? 129.862 172.303 139.632 1.00 89.85  ? 310 PHE A C   1 
ATOM   5855 O  O   . PHE B 1 310 ? 129.797 173.360 138.999 1.00 89.85  ? 310 PHE A O   1 
ATOM   5856 C  CB  . PHE B 1 310 ? 128.843 171.014 137.723 1.00 89.85  ? 310 PHE A CB  1 
ATOM   5857 C  CG  . PHE B 1 310 ? 130.012 170.395 137.015 1.00 89.85  ? 310 PHE A CG  1 
ATOM   5858 C  CD1 . PHE B 1 310 ? 130.406 169.100 137.306 1.00 89.85  ? 310 PHE A CD1 1 
ATOM   5859 C  CD2 . PHE B 1 310 ? 130.724 171.109 136.066 1.00 89.85  ? 310 PHE A CD2 1 
ATOM   5860 C  CE1 . PHE B 1 310 ? 131.483 168.527 136.661 1.00 89.85  ? 310 PHE A CE1 1 
ATOM   5861 C  CE2 . PHE B 1 310 ? 131.802 170.541 135.417 1.00 89.85  ? 310 PHE A CE2 1 
ATOM   5862 C  CZ  . PHE B 1 310 ? 132.182 169.248 135.715 1.00 89.85  ? 310 PHE A CZ  1 
ATOM   5863 N  N   . ASN B 1 311 ? 130.657 172.143 140.687 1.00 106.10 ? 311 ASN A N   1 
ATOM   5864 C  CA  . ASN B 1 311 ? 131.540 173.201 141.169 1.00 106.10 ? 311 ASN A CA  1 
ATOM   5865 C  C   . ASN B 1 311 ? 132.828 173.143 140.359 1.00 106.10 ? 311 ASN A C   1 
ATOM   5866 O  O   . ASN B 1 311 ? 133.689 172.293 140.598 1.00 106.10 ? 311 ASN A O   1 
ATOM   5867 C  CB  . ASN B 1 311 ? 131.808 173.044 142.661 1.00 106.10 ? 311 ASN A CB  1 
ATOM   5868 C  CG  . ASN B 1 311 ? 130.560 173.227 143.499 1.00 106.10 ? 311 ASN A CG  1 
ATOM   5869 O  OD1 . ASN B 1 311 ? 129.484 173.514 142.975 1.00 106.10 ? 311 ASN A OD1 1 
ATOM   5870 N  ND2 . ASN B 1 311 ? 130.697 173.062 144.809 1.00 106.10 ? 311 ASN A ND2 1 
ATOM   5871 N  N   . PHE B 1 312 ? 132.957 174.051 139.389 1.00 121.73 ? 312 PHE A N   1 
ATOM   5872 C  CA  . PHE B 1 312 ? 134.162 174.089 138.568 1.00 121.73 ? 312 PHE A CA  1 
ATOM   5873 C  C   . PHE B 1 312 ? 135.390 174.448 139.394 1.00 121.73 ? 312 PHE A C   1 
ATOM   5874 O  O   . PHE B 1 312 ? 136.493 173.970 139.105 1.00 121.73 ? 312 PHE A O   1 
ATOM   5875 C  CB  . PHE B 1 312 ? 133.983 175.080 137.419 1.00 121.73 ? 312 PHE A CB  1 
ATOM   5876 C  CG  . PHE B 1 312 ? 134.941 174.870 136.283 1.00 121.73 ? 312 PHE A CG  1 
ATOM   5877 C  CD1 . PHE B 1 312 ? 134.908 173.704 135.538 1.00 121.73 ? 312 PHE A CD1 1 
ATOM   5878 C  CD2 . PHE B 1 312 ? 135.875 175.840 135.958 1.00 121.73 ? 312 PHE A CD2 1 
ATOM   5879 C  CE1 . PHE B 1 312 ? 135.788 173.508 134.491 1.00 121.73 ? 312 PHE A CE1 1 
ATOM   5880 C  CE2 . PHE B 1 312 ? 136.758 175.650 134.912 1.00 121.73 ? 312 PHE A CE2 1 
ATOM   5881 C  CZ  . PHE B 1 312 ? 136.714 174.483 134.178 1.00 121.73 ? 312 PHE A CZ  1 
ATOM   5882 N  N   . LYS B 1 313 ? 135.221 175.290 140.416 1.00 124.17 ? 313 LYS A N   1 
ATOM   5883 C  CA  . LYS B 1 313 ? 136.340 175.633 141.286 1.00 124.17 ? 313 LYS A CA  1 
ATOM   5884 C  C   . LYS B 1 313 ? 136.841 174.413 142.049 1.00 124.17 ? 313 LYS A C   1 
ATOM   5885 O  O   . LYS B 1 313 ? 138.053 174.225 142.205 1.00 124.17 ? 313 LYS A O   1 
ATOM   5886 C  CB  . LYS B 1 313 ? 135.932 176.743 142.255 1.00 124.17 ? 313 LYS A CB  1 
ATOM   5887 C  CG  . LYS B 1 313 ? 135.014 177.793 141.650 1.00 124.17 ? 313 LYS A CG  1 
ATOM   5888 C  CD  . LYS B 1 313 ? 135.691 178.533 140.506 1.00 124.17 ? 313 LYS A CD  1 
ATOM   5889 C  CE  . LYS B 1 313 ? 134.682 179.315 139.680 1.00 124.17 ? 313 LYS A CE  1 
ATOM   5890 N  NZ  . LYS B 1 313 ? 135.291 179.880 138.446 1.00 124.17 ? 313 LYS A NZ  1 
ATOM   5891 N  N   . GLU B 1 314 ? 135.922 173.572 142.533 1.00 119.70 ? 314 GLU A N   1 
ATOM   5892 C  CA  . GLU B 1 314 ? 136.317 172.366 143.250 1.00 119.70 ? 314 GLU A CA  1 
ATOM   5893 C  C   . GLU B 1 314 ? 137.029 171.364 142.351 1.00 119.70 ? 314 GLU A C   1 
ATOM   5894 O  O   . GLU B 1 314 ? 137.770 170.516 142.858 1.00 119.70 ? 314 GLU A O   1 
ATOM   5895 C  CB  . GLU B 1 314 ? 135.093 171.711 143.891 1.00 119.70 ? 314 GLU A CB  1 
ATOM   5896 N  N   . MET B 1 315 ? 136.808 171.431 141.037 1.00 120.04 ? 315 MET A N   1 
ATOM   5897 C  CA  . MET B 1 315 ? 137.525 170.551 140.120 1.00 120.04 ? 315 MET A CA  1 
ATOM   5898 C  C   . MET B 1 315 ? 139.017 170.860 140.122 1.00 120.04 ? 315 MET A C   1 
ATOM   5899 O  O   . MET B 1 315 ? 139.845 169.967 140.339 1.00 120.04 ? 315 MET A O   1 
ATOM   5900 C  CB  . MET B 1 315 ? 136.945 170.687 138.711 1.00 120.04 ? 315 MET A CB  1 
ATOM   5901 C  CG  . MET B 1 315 ? 137.407 169.618 137.734 1.00 120.04 ? 315 MET A CG  1 
ATOM   5902 S  SD  . MET B 1 315 ? 137.333 170.177 136.021 1.00 120.04 ? 315 MET A SD  1 
ATOM   5903 C  CE  . MET B 1 315 ? 137.346 168.614 135.149 1.00 120.04 ? 315 MET A CE  1 
ATOM   5904 N  N   . PHE B 1 316 ? 139.368 172.131 139.916 1.00 123.65 ? 316 PHE A N   1 
ATOM   5905 C  CA  . PHE B 1 316 ? 140.747 172.633 139.821 1.00 123.65 ? 316 PHE A CA  1 
ATOM   5906 C  C   . PHE B 1 316 ? 141.770 171.612 139.322 1.00 123.65 ? 316 PHE A C   1 
ATOM   5907 O  O   . PHE B 1 316 ? 141.597 171.014 138.260 1.00 123.65 ? 316 PHE A O   1 
ATOM   5908 C  CB  . PHE B 1 316 ? 141.195 173.197 141.178 1.00 123.65 ? 316 PHE A CB  1 
ATOM   5909 C  CG  . PHE B 1 316 ? 141.633 172.152 142.169 1.00 123.65 ? 316 PHE A CG  1 
ATOM   5910 C  CD1 . PHE B 1 316 ? 140.703 171.484 142.947 1.00 123.65 ? 316 PHE A CD1 1 
ATOM   5911 C  CD2 . PHE B 1 316 ? 142.976 171.858 142.341 1.00 123.65 ? 316 PHE A CD2 1 
ATOM   5912 C  CE1 . PHE B 1 316 ? 141.102 170.530 143.864 1.00 123.65 ? 316 PHE A CE1 1 
ATOM   5913 C  CE2 . PHE B 1 316 ? 143.381 170.905 143.256 1.00 123.65 ? 316 PHE A CE2 1 
ATOM   5914 C  CZ  . PHE B 1 316 ? 142.442 170.241 144.019 1.00 123.65 ? 316 PHE A CZ  1 
ATOM   5915 N  N   . THR B 1 321 ? 146.605 169.683 151.082 1.00 113.94 ? 321 THR A N   1 
ATOM   5916 C  CA  . THR B 1 321 ? 145.476 170.186 151.855 1.00 113.94 ? 321 THR A CA  1 
ATOM   5917 C  C   . THR B 1 321 ? 144.258 169.284 151.693 1.00 113.94 ? 321 THR A C   1 
ATOM   5918 O  O   . THR B 1 321 ? 143.542 169.366 150.695 1.00 113.94 ? 321 THR A O   1 
ATOM   5919 C  CB  . THR B 1 321 ? 145.101 171.621 151.441 1.00 113.94 ? 321 THR A CB  1 
ATOM   5920 N  N   . LYS B 1 322 ? 144.028 168.423 152.682 1.00 114.79 ? 322 LYS A N   1 
ATOM   5921 C  CA  . LYS B 1 322 ? 142.917 167.483 152.661 1.00 114.79 ? 322 LYS A CA  1 
ATOM   5922 C  C   . LYS B 1 322 ? 142.076 167.654 153.916 1.00 114.79 ? 322 LYS A C   1 
ATOM   5923 O  O   . LYS B 1 322 ? 142.612 167.824 155.015 1.00 114.79 ? 322 LYS A O   1 
ATOM   5924 C  CB  . LYS B 1 322 ? 143.414 166.035 152.557 1.00 114.79 ? 322 LYS A CB  1 
ATOM   5925 N  N   . THR B 1 323 ? 140.758 167.609 153.745 1.00 116.00 ? 323 THR A N   1 
ATOM   5926 C  CA  . THR B 1 323 ? 139.846 167.722 154.871 1.00 116.00 ? 323 THR A CA  1 
ATOM   5927 C  C   . THR B 1 323 ? 139.704 166.377 155.580 1.00 116.00 ? 323 THR A C   1 
ATOM   5928 O  O   . THR B 1 323 ? 140.207 165.345 155.128 1.00 116.00 ? 323 THR A O   1 
ATOM   5929 C  CB  . THR B 1 323 ? 138.478 168.224 154.410 1.00 116.00 ? 323 THR A CB  1 
ATOM   5930 O  OG1 . THR B 1 323 ? 137.682 168.559 155.554 1.00 116.00 ? 323 THR A OG1 1 
ATOM   5931 C  CG2 . THR B 1 323 ? 137.763 167.153 153.605 1.00 116.00 ? 323 THR A CG2 1 
ATOM   5932 N  N   . VAL B 1 324 ? 139.003 166.402 156.715 1.00 114.08 ? 324 VAL A N   1 
ATOM   5933 C  CA  . VAL B 1 324 ? 138.808 165.184 157.498 1.00 114.08 ? 324 VAL A CA  1 
ATOM   5934 C  C   . VAL B 1 324 ? 137.970 164.176 156.723 1.00 114.08 ? 324 VAL A C   1 
ATOM   5935 O  O   . VAL B 1 324 ? 138.229 162.967 156.767 1.00 114.08 ? 324 VAL A O   1 
ATOM   5936 C  CB  . VAL B 1 324 ? 138.173 165.522 158.860 1.00 114.08 ? 324 VAL A CB  1 
ATOM   5937 C  CG1 . VAL B 1 324 ? 138.131 164.288 159.747 1.00 114.08 ? 324 VAL A CG1 1 
ATOM   5938 C  CG2 . VAL B 1 324 ? 138.942 166.646 159.536 1.00 114.08 ? 324 VAL A CG2 1 
ATOM   5939 N  N   . GLN B 1 325 ? 136.947 164.654 156.009 1.00 114.88 ? 325 GLN A N   1 
ATOM   5940 C  CA  . GLN B 1 325 ? 136.091 163.753 155.243 1.00 114.88 ? 325 GLN A CA  1 
ATOM   5941 C  C   . GLN B 1 325 ? 136.873 163.050 154.140 1.00 114.88 ? 325 GLN A C   1 
ATOM   5942 O  O   . GLN B 1 325 ? 136.670 161.855 153.888 1.00 114.88 ? 325 GLN A O   1 
ATOM   5943 C  CB  . GLN B 1 325 ? 134.911 164.528 154.657 1.00 114.88 ? 325 GLN A CB  1 
ATOM   5944 C  CG  . GLN B 1 325 ? 133.887 163.662 153.941 1.00 114.88 ? 325 GLN A CG  1 
ATOM   5945 C  CD  . GLN B 1 325 ? 132.889 163.034 154.895 1.00 114.88 ? 325 GLN A CD  1 
ATOM   5946 O  OE1 . GLN B 1 325 ? 132.855 163.363 156.081 1.00 114.88 ? 325 GLN A OE1 1 
ATOM   5947 N  NE2 . GLN B 1 325 ? 132.067 162.126 154.380 1.00 114.88 ? 325 GLN A NE2 1 
ATOM   5948 N  N   . GLN B 1 326 ? 137.763 163.779 153.462 1.00 113.13 ? 326 GLN A N   1 
ATOM   5949 C  CA  . GLN B 1 326 ? 138.580 163.168 152.418 1.00 113.13 ? 326 GLN A CA  1 
ATOM   5950 C  C   . GLN B 1 326 ? 139.500 162.098 152.993 1.00 113.13 ? 326 GLN A C   1 
ATOM   5951 O  O   . GLN B 1 326 ? 139.645 161.014 152.413 1.00 113.13 ? 326 GLN A O   1 
ATOM   5952 C  CB  . GLN B 1 326 ? 139.386 164.242 151.688 1.00 113.13 ? 326 GLN A CB  1 
ATOM   5953 C  CG  . GLN B 1 326 ? 138.562 165.071 150.714 1.00 113.13 ? 326 GLN A CG  1 
ATOM   5954 C  CD  . GLN B 1 326 ? 139.202 166.406 150.394 1.00 113.13 ? 326 GLN A CD  1 
ATOM   5955 O  OE1 . GLN B 1 326 ? 140.258 166.745 150.926 1.00 113.13 ? 326 GLN A OE1 1 
ATOM   5956 N  NE2 . GLN B 1 326 ? 138.562 167.175 149.521 1.00 113.13 ? 326 GLN A NE2 1 
ATOM   5957 N  N   . LYS B 1 327 ? 140.123 162.379 154.138 1.00 113.42 ? 327 LYS A N   1 
ATOM   5958 C  CA  . LYS B 1 327 ? 140.965 161.375 154.779 1.00 113.42 ? 327 LYS A CA  1 
ATOM   5959 C  C   . LYS B 1 327 ? 140.149 160.153 155.175 1.00 113.42 ? 327 LYS A C   1 
ATOM   5960 O  O   . LYS B 1 327 ? 140.594 159.013 154.993 1.00 113.42 ? 327 LYS A O   1 
ATOM   5961 C  CB  . LYS B 1 327 ? 141.662 161.975 156.000 1.00 113.42 ? 327 LYS A CB  1 
ATOM   5962 C  CG  . LYS B 1 327 ? 142.536 163.178 155.686 1.00 113.42 ? 327 LYS A CG  1 
ATOM   5963 C  CD  . LYS B 1 327 ? 143.309 163.634 156.911 1.00 113.42 ? 327 LYS A CD  1 
ATOM   5964 C  CE  . LYS B 1 327 ? 143.766 165.076 156.768 1.00 113.42 ? 327 LYS A CE  1 
ATOM   5965 N  NZ  . LYS B 1 327 ? 142.626 166.029 156.852 1.00 113.42 ? 327 LYS A NZ  1 
ATOM   5966 N  N   . ALA B 1 328 ? 138.944 160.371 155.706 1.00 111.60 ? 328 ALA A N   1 
ATOM   5967 C  CA  . ALA B 1 328 ? 138.098 159.255 156.116 1.00 111.60 ? 328 ALA A CA  1 
ATOM   5968 C  C   . ALA B 1 328 ? 137.706 158.386 154.928 1.00 111.60 ? 328 ALA A C   1 
ATOM   5969 O  O   . ALA B 1 328 ? 137.766 157.153 155.007 1.00 111.60 ? 328 ALA A O   1 
ATOM   5970 C  CB  . ALA B 1 328 ? 136.854 159.777 156.833 1.00 111.60 ? 328 ALA A CB  1 
ATOM   5971 N  N   . CYS B 1 329 ? 137.307 159.005 153.814 1.00 106.55 ? 329 CYS A N   1 
ATOM   5972 C  CA  . CYS B 1 329 ? 136.888 158.210 152.663 1.00 106.55 ? 329 CYS A CA  1 
ATOM   5973 C  C   . CYS B 1 329 ? 138.073 157.493 152.028 1.00 106.55 ? 329 CYS A C   1 
ATOM   5974 O  O   . CYS B 1 329 ? 137.939 156.353 151.566 1.00 106.55 ? 329 CYS A O   1 
ATOM   5975 C  CB  . CYS B 1 329 ? 136.167 159.079 151.633 1.00 106.55 ? 329 CYS A CB  1 
ATOM   5976 S  SG  . CYS B 1 329 ? 137.154 160.362 150.848 1.00 106.55 ? 329 CYS A SG  1 
ATOM   5977 N  N   . ALA B 1 330 ? 139.244 158.138 151.997 1.00 104.02 ? 330 ALA A N   1 
ATOM   5978 C  CA  . ALA B 1 330 ? 140.438 157.459 151.506 1.00 104.02 ? 330 ALA A CA  1 
ATOM   5979 C  C   . ALA B 1 330 ? 140.781 156.260 152.381 1.00 104.02 ? 330 ALA A C   1 
ATOM   5980 O  O   . ALA B 1 330 ? 141.147 155.194 151.872 1.00 104.02 ? 330 ALA A O   1 
ATOM   5981 C  CB  . ALA B 1 330 ? 141.612 158.435 151.445 1.00 104.02 ? 330 ALA A CB  1 
ATOM   5982 N  N   . GLU B 1 331 ? 140.656 156.416 153.701 1.00 101.94 ? 331 GLU A N   1 
ATOM   5983 C  CA  . GLU B 1 331 ? 140.901 155.303 154.610 1.00 101.94 ? 331 GLU A CA  1 
ATOM   5984 C  C   . GLU B 1 331 ? 139.908 154.175 154.357 1.00 101.94 ? 331 GLU A C   1 
ATOM   5985 O  O   . GLU B 1 331 ? 140.284 152.998 154.340 1.00 101.94 ? 331 GLU A O   1 
ATOM   5986 C  CB  . GLU B 1 331 ? 140.815 155.804 156.055 1.00 101.94 ? 331 GLU A CB  1 
ATOM   5987 C  CG  . GLU B 1 331 ? 140.850 154.763 157.182 1.00 101.94 ? 331 GLU A CG  1 
ATOM   5988 C  CD  . GLU B 1 331 ? 141.761 153.579 156.906 1.00 101.94 ? 331 GLU A CD  1 
ATOM   5989 O  OE1 . GLU B 1 331 ? 141.249 152.459 156.703 1.00 101.94 ? 331 GLU A OE1 1 
ATOM   5990 O  OE2 . GLU B 1 331 ? 142.995 153.771 156.894 1.00 101.94 ? 331 GLU A OE2 1 
ATOM   5991 N  N   . VAL B 1 332 ? 138.636 154.518 154.134 1.00 98.89  ? 332 VAL A N   1 
ATOM   5992 C  CA  . VAL B 1 332 ? 137.617 153.499 153.881 1.00 98.89  ? 332 VAL A CA  1 
ATOM   5993 C  C   . VAL B 1 332 ? 137.933 152.731 152.602 1.00 98.89  ? 332 VAL A C   1 
ATOM   5994 O  O   . VAL B 1 332 ? 137.857 151.495 152.562 1.00 98.89  ? 332 VAL A O   1 
ATOM   5995 C  CB  . VAL B 1 332 ? 136.220 154.141 153.821 1.00 98.89  ? 332 VAL A CB  1 
ATOM   5996 C  CG1 . VAL B 1 332 ? 135.208 153.154 153.265 1.00 98.89  ? 332 VAL A CG1 1 
ATOM   5997 C  CG2 . VAL B 1 332 ? 135.797 154.610 155.202 1.00 98.89  ? 332 VAL A CG2 1 
ATOM   5998 N  N   . ILE B 1 333 ? 138.288 153.453 151.536 1.00 93.07  ? 333 ILE A N   1 
ATOM   5999 C  CA  . ILE B 1 333 ? 138.635 152.795 150.278 1.00 93.07  ? 333 ILE A CA  1 
ATOM   6000 C  C   . ILE B 1 333 ? 139.844 151.889 150.467 1.00 93.07  ? 333 ILE A C   1 
ATOM   6001 O  O   . ILE B 1 333 ? 139.861 150.742 150.000 1.00 93.07  ? 333 ILE A O   1 
ATOM   6002 C  CB  . ILE B 1 333 ? 138.882 153.840 149.175 1.00 93.07  ? 333 ILE A CB  1 
ATOM   6003 C  CG1 . ILE B 1 333 ? 137.615 154.644 148.906 1.00 93.07  ? 333 ILE A CG1 1 
ATOM   6004 C  CG2 . ILE B 1 333 ? 139.338 153.160 147.900 1.00 93.07  ? 333 ILE A CG2 1 
ATOM   6005 C  CD1 . ILE B 1 333 ? 136.532 153.838 148.248 1.00 93.07  ? 333 ILE A CD1 1 
ATOM   6006 N  N   . LYS B 1 334 ? 140.869 152.382 151.163 1.00 94.76  ? 334 LYS A N   1 
ATOM   6007 C  CA  . LYS B 1 334 ? 142.069 151.583 151.382 1.00 94.76  ? 334 LYS A CA  1 
ATOM   6008 C  C   . LYS B 1 334 ? 141.749 150.316 152.164 1.00 94.76  ? 334 LYS A C   1 
ATOM   6009 O  O   . LYS B 1 334 ? 142.237 149.229 151.832 1.00 94.76  ? 334 LYS A O   1 
ATOM   6010 C  CB  . LYS B 1 334 ? 143.121 152.416 152.112 1.00 94.76  ? 334 LYS A CB  1 
ATOM   6011 C  CG  . LYS B 1 334 ? 144.553 151.967 151.876 1.00 94.76  ? 334 LYS A CG  1 
ATOM   6012 C  CD  . LYS B 1 334 ? 145.542 152.991 152.413 1.00 94.76  ? 334 LYS A CD  1 
ATOM   6013 C  CE  . LYS B 1 334 ? 145.096 153.540 153.760 1.00 94.76  ? 334 LYS A CE  1 
ATOM   6014 N  NZ  . LYS B 1 334 ? 145.852 154.763 154.144 1.00 94.76  ? 334 LYS A NZ  1 
ATOM   6015 N  N   . GLN B 1 335 ? 140.925 150.433 153.207 1.00 94.94  ? 335 GLN A N   1 
ATOM   6016 C  CA  . GLN B 1 335 ? 140.655 149.265 154.038 1.00 94.94  ? 335 GLN A CA  1 
ATOM   6017 C  C   . GLN B 1 335 ? 139.745 148.272 153.328 1.00 94.94  ? 335 GLN A C   1 
ATOM   6018 O  O   . GLN B 1 335 ? 139.878 147.065 153.542 1.00 94.94  ? 335 GLN A O   1 
ATOM   6019 C  CB  . GLN B 1 335 ? 140.104 149.690 155.406 1.00 94.94  ? 335 GLN A CB  1 
ATOM   6020 C  CG  . GLN B 1 335 ? 138.774 150.431 155.449 1.00 94.94  ? 335 GLN A CG  1 
ATOM   6021 C  CD  . GLN B 1 335 ? 137.576 149.538 155.220 1.00 94.94  ? 335 GLN A CD  1 
ATOM   6022 O  OE1 . GLN B 1 335 ? 137.446 148.481 155.837 1.00 94.94  ? 335 GLN A OE1 1 
ATOM   6023 N  NE2 . GLN B 1 335 ? 136.671 149.979 154.360 1.00 94.94  ? 335 GLN A NE2 1 
ATOM   6024 N  N   . GLU B 1 336 ? 138.856 148.737 152.444 1.00 90.81  ? 336 GLU A N   1 
ATOM   6025 C  CA  . GLU B 1 336 ? 138.177 147.795 151.556 1.00 90.81  ? 336 GLU A CA  1 
ATOM   6026 C  C   . GLU B 1 336 ? 139.172 147.099 150.636 1.00 90.81  ? 336 GLU A C   1 
ATOM   6027 O  O   . GLU B 1 336 ? 139.041 145.901 150.353 1.00 90.81  ? 336 GLU A O   1 
ATOM   6028 C  CB  . GLU B 1 336 ? 137.097 148.494 150.729 1.00 90.81  ? 336 GLU A CB  1 
ATOM   6029 C  CG  . GLU B 1 336 ? 135.893 148.961 151.517 1.00 90.81  ? 336 GLU A CG  1 
ATOM   6030 C  CD  . GLU B 1 336 ? 134.824 149.571 150.636 1.00 90.81  ? 336 GLU A CD  1 
ATOM   6031 O  OE1 . GLU B 1 336 ? 135.069 149.717 149.421 1.00 90.81  ? 336 GLU A OE1 1 
ATOM   6032 O  OE2 . GLU B 1 336 ? 133.739 149.902 151.157 1.00 90.81  ? 336 GLU A OE2 1 
ATOM   6033 N  N   . TYR B 1 337 ? 140.173 147.839 150.154 1.00 84.51  ? 337 TYR A N   1 
ATOM   6034 C  CA  . TYR B 1 337 ? 141.174 147.237 149.279 1.00 84.51  ? 337 TYR A CA  1 
ATOM   6035 C  C   . TYR B 1 337 ? 141.942 146.132 149.996 1.00 84.51  ? 337 TYR A C   1 
ATOM   6036 O  O   . TYR B 1 337 ? 142.189 145.067 149.420 1.00 84.51  ? 337 TYR A O   1 
ATOM   6037 C  CB  . TYR B 1 337 ? 142.128 148.309 148.756 1.00 84.51  ? 337 TYR A CB  1 
ATOM   6038 C  CG  . TYR B 1 337 ? 143.123 147.799 147.742 1.00 84.51  ? 337 TYR A CG  1 
ATOM   6039 C  CD1 . TYR B 1 337 ? 142.698 147.264 146.535 1.00 84.51  ? 337 TYR A CD1 1 
ATOM   6040 C  CD2 . TYR B 1 337 ? 144.486 147.857 147.990 1.00 84.51  ? 337 TYR A CD2 1 
ATOM   6041 C  CE1 . TYR B 1 337 ? 143.602 146.799 145.604 1.00 84.51  ? 337 TYR A CE1 1 
ATOM   6042 C  CE2 . TYR B 1 337 ? 145.399 147.395 147.065 1.00 84.51  ? 337 TYR A CE2 1 
ATOM   6043 C  CZ  . TYR B 1 337 ? 144.952 146.867 145.874 1.00 84.51  ? 337 TYR A CZ  1 
ATOM   6044 O  OH  . TYR B 1 337 ? 145.859 146.404 144.949 1.00 84.51  ? 337 TYR A OH  1 
ATOM   6045 N  N   . GLN B 1 338 ? 142.332 146.364 151.253 1.00 88.83  ? 338 GLN A N   1 
ATOM   6046 C  CA  . GLN B 1 338 ? 142.957 145.277 152.007 1.00 88.83  ? 338 GLN A CA  1 
ATOM   6047 C  C   . GLN B 1 338 ? 141.957 144.174 152.336 1.00 88.83  ? 338 GLN A C   1 
ATOM   6048 O  O   . GLN B 1 338 ? 142.344 143.004 152.437 1.00 88.83  ? 338 GLN A O   1 
ATOM   6049 C  CB  . GLN B 1 338 ? 143.629 145.758 153.299 1.00 88.83  ? 338 GLN A CB  1 
ATOM   6050 C  CG  . GLN B 1 338 ? 144.931 146.533 153.112 1.00 88.83  ? 338 GLN A CG  1 
ATOM   6051 C  CD  . GLN B 1 338 ? 144.750 148.030 153.139 1.00 88.83  ? 338 GLN A CD  1 
ATOM   6052 O  OE1 . GLN B 1 338 ? 143.795 148.535 153.723 1.00 88.83  ? 338 GLN A OE1 1 
ATOM   6053 N  NE2 . GLN B 1 338 ? 145.667 148.752 152.506 1.00 88.83  ? 338 GLN A NE2 1 
ATOM   6054 N  N   . LYS B 1 339 ? 140.679 144.519 152.511 1.00 89.43  ? 339 LYS A N   1 
ATOM   6055 C  CA  . LYS B 1 339 ? 139.655 143.501 152.714 1.00 89.43  ? 339 LYS A CA  1 
ATOM   6056 C  C   . LYS B 1 339 ? 139.557 142.569 151.516 1.00 89.43  ? 339 LYS A C   1 
ATOM   6057 O  O   . LYS B 1 339 ? 139.210 141.393 151.671 1.00 89.43  ? 339 LYS A O   1 
ATOM   6058 C  CB  . LYS B 1 339 ? 138.304 144.162 152.985 1.00 89.43  ? 339 LYS A CB  1 
ATOM   6059 C  CG  . LYS B 1 339 ? 137.231 143.214 153.491 1.00 89.43  ? 339 LYS A CG  1 
ATOM   6060 C  CD  . LYS B 1 339 ? 136.147 143.964 154.245 1.00 89.43  ? 339 LYS A CD  1 
ATOM   6061 C  CE  . LYS B 1 339 ? 134.984 144.315 153.330 1.00 89.43  ? 339 LYS A CE  1 
ATOM   6062 N  NZ  . LYS B 1 339 ? 134.042 145.278 153.964 1.00 89.43  ? 339 LYS A NZ  1 
ATOM   6063 N  N   . LEU B 1 340 ? 139.850 143.077 150.317 1.00 83.42  ? 340 LEU A N   1 
ATOM   6064 C  CA  . LEU B 1 340 ? 139.910 142.206 149.147 1.00 83.42  ? 340 LEU A CA  1 
ATOM   6065 C  C   . LEU B 1 340 ? 140.990 141.145 149.311 1.00 83.42  ? 340 LEU A C   1 
ATOM   6066 O  O   . LEU B 1 340 ? 140.799 139.986 148.923 1.00 83.42  ? 340 LEU A O   1 
ATOM   6067 C  CB  . LEU B 1 340 ? 140.153 143.028 147.882 1.00 83.42  ? 340 LEU A CB  1 
ATOM   6068 C  CG  . LEU B 1 340 ? 138.911 143.629 147.226 1.00 83.42  ? 340 LEU A CG  1 
ATOM   6069 C  CD1 . LEU B 1 340 ? 139.222 144.076 145.811 1.00 83.42  ? 340 LEU A CD1 1 
ATOM   6070 C  CD2 . LEU B 1 340 ? 137.765 142.633 147.232 1.00 83.42  ? 340 LEU A CD2 1 
ATOM   6071 N  N   . GLY B 1 341 ? 142.131 141.520 149.883 1.00 81.43  ? 341 GLY A N   1 
ATOM   6072 C  CA  . GLY B 1 341 ? 143.180 140.575 150.177 1.00 81.43  ? 341 GLY A CA  1 
ATOM   6073 C  C   . GLY B 1 341 ? 144.385 140.731 149.274 1.00 81.43  ? 341 GLY A C   1 
ATOM   6074 O  O   . GLY B 1 341 ? 144.329 141.386 148.228 1.00 81.43  ? 341 GLY A O   1 
ATOM   6075 N  N   . PRO B 1 342 ? 145.505 140.131 149.668 1.00 75.56  ? 342 PRO A N   1 
ATOM   6076 C  CA  . PRO B 1 342 ? 146.709 140.198 148.835 1.00 75.56  ? 342 PRO A CA  1 
ATOM   6077 C  C   . PRO B 1 342 ? 146.528 139.434 147.534 1.00 75.56  ? 342 PRO A C   1 
ATOM   6078 O  O   . PRO B 1 342 ? 145.752 138.480 147.446 1.00 75.56  ? 342 PRO A O   1 
ATOM   6079 C  CB  . PRO B 1 342 ? 147.786 139.554 149.715 1.00 75.56  ? 342 PRO A CB  1 
ATOM   6080 C  CG  . PRO B 1 342 ? 147.029 138.658 150.634 1.00 75.56  ? 342 PRO A CG  1 
ATOM   6081 C  CD  . PRO B 1 342 ? 145.719 139.343 150.894 1.00 75.56  ? 342 PRO A CD  1 
ATOM   6082 N  N   . ILE B 1 343 ? 147.265 139.873 146.512 1.00 70.01  ? 343 ILE A N   1 
ATOM   6083 C  CA  . ILE B 1 343 ? 147.149 139.270 145.191 1.00 70.01  ? 343 ILE A CA  1 
ATOM   6084 C  C   . ILE B 1 343 ? 147.651 137.831 145.231 1.00 70.01  ? 343 ILE A C   1 
ATOM   6085 O  O   . ILE B 1 343 ? 148.486 137.458 146.066 1.00 70.01  ? 343 ILE A O   1 
ATOM   6086 C  CB  . ILE B 1 343 ? 147.917 140.108 144.151 1.00 70.01  ? 343 ILE A CB  1 
ATOM   6087 C  CG1 . ILE B 1 343 ? 147.402 139.823 142.739 1.00 70.01  ? 343 ILE A CG1 1 
ATOM   6088 C  CG2 . ILE B 1 343 ? 149.413 139.852 144.244 1.00 70.01  ? 343 ILE A CG2 1 
ATOM   6089 C  CD1 . ILE B 1 343 ? 147.872 140.823 141.708 1.00 70.01  ? 343 ILE A CD1 1 
ATOM   6090 N  N   . ARG B 1 344 ? 147.122 137.008 144.331 1.00 66.29  ? 344 ARG A N   1 
ATOM   6091 C  CA  . ARG B 1 344 ? 147.454 135.594 144.259 1.00 66.29  ? 344 ARG A CA  1 
ATOM   6092 C  C   . ARG B 1 344 ? 148.075 135.270 142.907 1.00 66.29  ? 344 ARG A C   1 
ATOM   6093 O  O   . ARG B 1 344 ? 148.105 136.096 141.992 1.00 66.29  ? 344 ARG A O   1 
ATOM   6094 C  CB  . ARG B 1 344 ? 146.214 134.722 144.493 1.00 66.29  ? 344 ARG A CB  1 
ATOM   6095 C  CG  . ARG B 1 344 ? 145.954 134.386 145.949 1.00 66.29  ? 344 ARG A CG  1 
ATOM   6096 C  CD  . ARG B 1 344 ? 144.527 133.909 146.153 1.00 66.29  ? 344 ARG A CD  1 
ATOM   6097 N  NE  . ARG B 1 344 ? 143.562 134.797 145.517 1.00 66.29  ? 344 ARG A NE  1 
ATOM   6098 C  CZ  . ARG B 1 344 ? 142.483 134.387 144.863 1.00 66.29  ? 344 ARG A CZ  1 
ATOM   6099 N  NH1 . ARG B 1 344 ? 142.198 133.102 144.739 1.00 66.29  ? 344 ARG A NH1 1 
ATOM   6100 N  NH2 . ARG B 1 344 ? 141.672 135.290 144.320 1.00 66.29  ? 344 ARG A NH2 1 
ATOM   6101 N  N   . TYR B 1 345 ? 148.581 134.040 142.797 1.00 64.36  ? 345 TYR A N   1 
ATOM   6102 C  CA  . TYR B 1 345 ? 149.200 133.595 141.553 1.00 64.36  ? 345 TYR A CA  1 
ATOM   6103 C  C   . TYR B 1 345 ? 148.179 133.501 140.425 1.00 64.36  ? 345 TYR A C   1 
ATOM   6104 O  O   . TYR B 1 345 ? 148.474 133.865 139.279 1.00 64.36  ? 345 TYR A O   1 
ATOM   6105 C  CB  . TYR B 1 345 ? 149.890 132.251 141.770 1.00 64.36  ? 345 TYR A CB  1 
ATOM   6106 C  CG  . TYR B 1 345 ? 150.014 131.417 140.521 1.00 64.36  ? 345 TYR A CG  1 
ATOM   6107 C  CD1 . TYR B 1 345 ? 150.894 131.774 139.510 1.00 64.36  ? 345 TYR A CD1 1 
ATOM   6108 C  CD2 . TYR B 1 345 ? 149.252 130.271 140.352 1.00 64.36  ? 345 TYR A CD2 1 
ATOM   6109 C  CE1 . TYR B 1 345 ? 151.011 131.013 138.366 1.00 64.36  ? 345 TYR A CE1 1 
ATOM   6110 C  CE2 . TYR B 1 345 ? 149.361 129.505 139.213 1.00 64.36  ? 345 TYR A CE2 1 
ATOM   6111 C  CZ  . TYR B 1 345 ? 150.242 129.879 138.222 1.00 64.36  ? 345 TYR A CZ  1 
ATOM   6112 O  OH  . TYR B 1 345 ? 150.356 129.118 137.083 1.00 64.36  ? 345 TYR A OH  1 
ATOM   6113 N  N   . GLN B 1 346 ? 146.977 133.004 140.725 1.00 60.83  ? 346 GLN A N   1 
ATOM   6114 C  CA  . GLN B 1 346 ? 145.941 132.922 139.701 1.00 60.83  ? 346 GLN A CA  1 
ATOM   6115 C  C   . GLN B 1 346 ? 145.584 134.303 139.173 1.00 60.83  ? 346 GLN A C   1 
ATOM   6116 O  O   . GLN B 1 346 ? 145.442 134.496 137.959 1.00 60.83  ? 346 GLN A O   1 
ATOM   6117 C  CB  . GLN B 1 346 ? 144.703 132.222 140.260 1.00 60.83  ? 346 GLN A CB  1 
ATOM   6118 C  CG  . GLN B 1 346 ? 144.972 130.831 140.801 1.00 60.83  ? 346 GLN A CG  1 
ATOM   6119 C  CD  . GLN B 1 346 ? 145.100 130.808 142.308 1.00 60.83  ? 346 GLN A CD  1 
ATOM   6120 O  OE1 . GLN B 1 346 ? 144.309 131.425 143.018 1.00 60.83  ? 346 GLN A OE1 1 
ATOM   6121 N  NE2 . GLN B 1 346 ? 146.104 130.096 142.805 1.00 60.83  ? 346 GLN A NE2 1 
ATOM   6122 N  N   . GLU B 1 347 ? 145.451 135.283 140.068 1.00 63.65  ? 347 GLU A N   1 
ATOM   6123 C  CA  . GLU B 1 347 ? 145.113 136.633 139.634 1.00 63.65  ? 347 GLU A CA  1 
ATOM   6124 C  C   . GLU B 1 347 ? 146.206 137.226 138.754 1.00 63.65  ? 347 GLU A C   1 
ATOM   6125 O  O   . GLU B 1 347 ? 145.912 137.845 137.727 1.00 63.65  ? 347 GLU A O   1 
ATOM   6126 C  CB  . GLU B 1 347 ? 144.852 137.524 140.848 1.00 63.65  ? 347 GLU A CB  1 
ATOM   6127 C  CG  . GLU B 1 347 ? 143.693 137.054 141.713 1.00 63.65  ? 347 GLU A CG  1 
ATOM   6128 C  CD  . GLU B 1 347 ? 143.351 138.034 142.816 1.00 63.65  ? 347 GLU A CD  1 
ATOM   6129 O  OE1 . GLU B 1 347 ? 143.575 139.248 142.626 1.00 63.65  ? 347 GLU A OE1 1 
ATOM   6130 O  OE2 . GLU B 1 347 ? 142.855 137.592 143.873 1.00 63.65  ? 347 GLU A OE2 1 
ATOM   6131 N  N   . ILE B 1 348 ? 147.473 137.038 139.128 1.00 57.23  ? 348 ILE A N   1 
ATOM   6132 C  CA  . ILE B 1 348 ? 148.552 137.648 138.356 1.00 57.23  ? 348 ILE A CA  1 
ATOM   6133 C  C   . ILE B 1 348 ? 148.698 136.971 136.996 1.00 57.23  ? 348 ILE A C   1 
ATOM   6134 O  O   . ILE B 1 348 ? 148.946 137.639 135.985 1.00 57.23  ? 348 ILE A O   1 
ATOM   6135 C  CB  . ILE B 1 348 ? 149.872 137.648 139.155 1.00 57.23  ? 348 ILE A CB  1 
ATOM   6136 C  CG1 . ILE B 1 348 ? 150.913 138.526 138.460 1.00 57.23  ? 348 ILE A CG1 1 
ATOM   6137 C  CG2 . ILE B 1 348 ? 150.421 136.251 139.345 1.00 57.23  ? 348 ILE A CG2 1 
ATOM   6138 C  CD1 . ILE B 1 348 ? 150.583 139.997 138.484 1.00 57.23  ? 348 ILE A CD1 1 
ATOM   6139 N  N   . VAL B 1 349 ? 148.531 135.646 136.933 1.00 56.22  ? 349 VAL A N   1 
ATOM   6140 C  CA  . VAL B 1 349 ? 148.635 134.980 135.636 1.00 56.22  ? 349 VAL A CA  1 
ATOM   6141 C  C   . VAL B 1 349 ? 147.451 135.350 134.747 1.00 56.22  ? 349 VAL A C   1 
ATOM   6142 O  O   . VAL B 1 349 ? 147.606 135.537 133.531 1.00 56.22  ? 349 VAL A O   1 
ATOM   6143 C  CB  . VAL B 1 349 ? 148.787 133.455 135.808 1.00 56.22  ? 349 VAL A CB  1 
ATOM   6144 C  CG1 . VAL B 1 349 ? 147.511 132.814 136.318 1.00 56.22  ? 349 VAL A CG1 1 
ATOM   6145 C  CG2 . VAL B 1 349 ? 149.214 132.821 134.496 1.00 56.22  ? 349 VAL A CG2 1 
ATOM   6146 N  N   . THR B 1 350 ? 146.255 135.486 135.333 1.00 54.71  ? 350 THR A N   1 
ATOM   6147 C  CA  . THR B 1 350 ? 145.106 135.941 134.559 1.00 54.71  ? 350 THR A CA  1 
ATOM   6148 C  C   . THR B 1 350 ? 145.326 137.351 134.035 1.00 54.71  ? 350 THR A C   1 
ATOM   6149 O  O   . THR B 1 350 ? 144.994 137.652 132.885 1.00 54.71  ? 350 THR A O   1 
ATOM   6150 C  CB  . THR B 1 350 ? 143.838 135.879 135.409 1.00 54.71  ? 350 THR A CB  1 
ATOM   6151 O  OG1 . THR B 1 350 ? 143.587 134.524 135.797 1.00 54.71  ? 350 THR A OG1 1 
ATOM   6152 C  CG2 . THR B 1 350 ? 142.647 136.405 134.629 1.00 54.71  ? 350 THR A CG2 1 
ATOM   6153 N  N   . LEU B 1 351 ? 145.894 138.228 134.864 1.00 53.16  ? 351 LEU A N   1 
ATOM   6154 C  CA  . LEU B 1 351 ? 146.185 139.587 134.423 1.00 53.16  ? 351 LEU A CA  1 
ATOM   6155 C  C   . LEU B 1 351 ? 147.208 139.595 133.297 1.00 53.16  ? 351 LEU A C   1 
ATOM   6156 O  O   . LEU B 1 351 ? 147.082 140.369 132.343 1.00 53.16  ? 351 LEU A O   1 
ATOM   6157 C  CB  . LEU B 1 351 ? 146.674 140.424 135.605 1.00 53.16  ? 351 LEU A CB  1 
ATOM   6158 C  CG  . LEU B 1 351 ? 146.868 141.923 135.382 1.00 53.16  ? 351 LEU A CG  1 
ATOM   6159 C  CD1 . LEU B 1 351 ? 146.356 142.696 136.581 1.00 53.16  ? 351 LEU A CD1 1 
ATOM   6160 C  CD2 . LEU B 1 351 ? 148.333 142.239 135.137 1.00 53.16  ? 351 LEU A CD2 1 
ATOM   6161 N  N   . VAL B 1 352 ? 148.234 138.746 133.390 1.00 50.22  ? 352 VAL A N   1 
ATOM   6162 C  CA  . VAL B 1 352 ? 149.251 138.694 132.341 1.00 50.22  ? 352 VAL A CA  1 
ATOM   6163 C  C   . VAL B 1 352 ? 148.636 138.237 131.023 1.00 50.22  ? 352 VAL A C   1 
ATOM   6164 O  O   . VAL B 1 352 ? 148.869 138.837 129.966 1.00 50.22  ? 352 VAL A O   1 
ATOM   6165 C  CB  . VAL B 1 352 ? 150.415 137.783 132.767 1.00 50.22  ? 352 VAL A CB  1 
ATOM   6166 C  CG1 . VAL B 1 352 ? 151.254 137.400 131.561 1.00 50.22  ? 352 VAL A CG1 1 
ATOM   6167 C  CG2 . VAL B 1 352 ? 151.269 138.479 133.810 1.00 50.22  ? 352 VAL A CG2 1 
ATOM   6168 N  N   . LEU B 1 353 ? 147.835 137.170 131.066 1.00 46.57  ? 353 LEU A N   1 
ATOM   6169 C  CA  . LEU B 1 353 ? 147.204 136.687 129.840 1.00 46.57  ? 353 LEU A CA  1 
ATOM   6170 C  C   . LEU B 1 353 ? 146.213 137.707 129.290 1.00 46.57  ? 353 LEU A C   1 
ATOM   6171 O  O   . LEU B 1 353 ? 146.091 137.872 128.072 1.00 46.57  ? 353 LEU A O   1 
ATOM   6172 C  CB  . LEU B 1 353 ? 146.523 135.343 130.091 1.00 46.57  ? 353 LEU A CB  1 
ATOM   6173 C  CG  . LEU B 1 353 ? 147.482 134.162 130.245 1.00 46.57  ? 353 LEU A CG  1 
ATOM   6174 C  CD1 . LEU B 1 353 ? 146.741 132.899 130.632 1.00 46.57  ? 353 LEU A CD1 1 
ATOM   6175 C  CD2 . LEU B 1 353 ? 148.262 133.947 128.963 1.00 46.57  ? 353 LEU A CD2 1 
ATOM   6176 N  N   . PHE B 1 354 ? 145.502 138.409 130.174 1.00 48.72  ? 354 PHE A N   1 
ATOM   6177 C  CA  . PHE B 1 354 ? 144.573 139.444 129.735 1.00 48.72  ? 354 PHE A CA  1 
ATOM   6178 C  C   . PHE B 1 354 ? 145.308 140.597 129.062 1.00 48.72  ? 354 PHE A C   1 
ATOM   6179 O  O   . PHE B 1 354 ? 144.837 141.139 128.057 1.00 48.72  ? 354 PHE A O   1 
ATOM   6180 C  CB  . PHE B 1 354 ? 143.758 139.934 130.933 1.00 48.72  ? 354 PHE A CB  1 
ATOM   6181 C  CG  . PHE B 1 354 ? 142.964 141.179 130.668 1.00 48.72  ? 354 PHE A CG  1 
ATOM   6182 C  CD1 . PHE B 1 354 ? 142.147 141.278 129.559 1.00 48.72  ? 354 PHE A CD1 1 
ATOM   6183 C  CD2 . PHE B 1 354 ? 143.028 142.248 131.544 1.00 48.72  ? 354 PHE A CD2 1 
ATOM   6184 C  CE1 . PHE B 1 354 ? 141.417 142.422 129.322 1.00 48.72  ? 354 PHE A CE1 1 
ATOM   6185 C  CE2 . PHE B 1 354 ? 142.300 143.393 131.313 1.00 48.72  ? 354 PHE A CE2 1 
ATOM   6186 C  CZ  . PHE B 1 354 ? 141.494 143.481 130.201 1.00 48.72  ? 354 PHE A CZ  1 
ATOM   6187 N  N   . ILE B 1 355 ? 146.461 140.990 129.606 1.00 45.98  ? 355 ILE A N   1 
ATOM   6188 C  CA  . ILE B 1 355 ? 147.258 142.042 128.980 1.00 45.98  ? 355 ILE A CA  1 
ATOM   6189 C  C   . ILE B 1 355 ? 147.761 141.585 127.618 1.00 45.98  ? 355 ILE A C   1 
ATOM   6190 O  O   . ILE B 1 355 ? 147.761 142.354 126.650 1.00 45.98  ? 355 ILE A O   1 
ATOM   6191 C  CB  . ILE B 1 355 ? 148.418 142.458 129.904 1.00 45.98  ? 355 ILE A CB  1 
ATOM   6192 C  CG1 . ILE B 1 355 ? 147.886 143.171 131.146 1.00 45.98  ? 355 ILE A CG1 1 
ATOM   6193 C  CG2 . ILE B 1 355 ? 149.394 143.353 129.167 1.00 45.98  ? 355 ILE A CG2 1 
ATOM   6194 C  CD1 . ILE B 1 355 ? 147.039 144.377 130.839 1.00 45.98  ? 355 ILE A CD1 1 
ATOM   6195 N  N   . ILE B 1 356 ? 148.195 140.327 127.522 1.00 49.51  ? 356 ILE A N   1 
ATOM   6196 C  CA  . ILE B 1 356 ? 148.651 139.797 126.238 1.00 49.51  ? 356 ILE A CA  1 
ATOM   6197 C  C   . ILE B 1 356 ? 147.512 139.795 125.225 1.00 49.51  ? 356 ILE A C   1 
ATOM   6198 O  O   . ILE B 1 356 ? 147.718 140.071 124.038 1.00 49.51  ? 356 ILE A O   1 
ATOM   6199 C  CB  . ILE B 1 356 ? 149.254 138.392 126.422 1.00 49.51  ? 356 ILE A CB  1 
ATOM   6200 C  CG1 . ILE B 1 356 ? 150.542 138.469 127.239 1.00 49.51  ? 356 ILE A CG1 1 
ATOM   6201 C  CG2 . ILE B 1 356 ? 149.526 137.744 125.077 1.00 49.51  ? 356 ILE A CG2 1 
ATOM   6202 C  CD1 . ILE B 1 356 ? 151.625 139.294 126.587 1.00 49.51  ? 356 ILE A CD1 1 
ATOM   6203 N  N   . MET B 1 357 ? 146.295 139.485 125.676 1.00 54.15  ? 357 MET A N   1 
ATOM   6204 C  CA  . MET B 1 357 ? 145.145 139.515 124.777 1.00 54.15  ? 357 MET A CA  1 
ATOM   6205 C  C   . MET B 1 357 ? 144.758 140.937 124.395 1.00 54.15  ? 357 MET A C   1 
ATOM   6206 O  O   . MET B 1 357 ? 144.234 141.159 123.298 1.00 54.15  ? 357 MET A O   1 
ATOM   6207 C  CB  . MET B 1 357 ? 143.951 138.810 125.413 1.00 54.15  ? 357 MET A CB  1 
ATOM   6208 C  CG  . MET B 1 357 ? 143.714 137.404 124.907 1.00 54.15  ? 357 MET A CG  1 
ATOM   6209 S  SD  . MET B 1 357 ? 142.284 136.659 125.704 1.00 54.15  ? 357 MET A SD  1 
ATOM   6210 C  CE  . MET B 1 357 ? 142.708 134.929 125.603 1.00 54.15  ? 357 MET A CE  1 
ATOM   6211 N  N   . ALA B 1 358 ? 144.976 141.905 125.287 1.00 55.85  ? 358 ALA A N   1 
ATOM   6212 C  CA  . ALA B 1 358 ? 144.696 143.296 124.950 1.00 55.85  ? 358 ALA A CA  1 
ATOM   6213 C  C   . ALA B 1 358 ? 145.554 143.746 123.776 1.00 55.85  ? 358 ALA A C   1 
ATOM   6214 O  O   . ALA B 1 358 ? 145.054 144.345 122.817 1.00 55.85  ? 358 ALA A O   1 
ATOM   6215 C  CB  . ALA B 1 358 ? 144.927 144.190 126.168 1.00 55.85  ? 358 ALA A CB  1 
ATOM   6216 N  N   . LEU B 1 359 ? 146.850 143.454 123.829 1.00 54.32  ? 359 LEU A N   1 
ATOM   6217 C  CA  . LEU B 1 359 ? 147.679 143.574 122.646 1.00 54.32  ? 359 LEU A CA  1 
ATOM   6218 C  C   . LEU B 1 359 ? 147.349 142.439 121.681 1.00 54.32  ? 359 LEU A C   1 
ATOM   6219 O  O   . LEU B 1 359 ? 146.607 141.510 122.008 1.00 54.32  ? 359 LEU A O   1 
ATOM   6220 C  CB  . LEU B 1 359 ? 149.160 143.552 123.017 1.00 54.32  ? 359 LEU A CB  1 
ATOM   6221 C  CG  . LEU B 1 359 ? 149.582 144.397 124.219 1.00 54.32  ? 359 LEU A CG  1 
ATOM   6222 C  CD1 . LEU B 1 359 ? 151.079 144.282 124.447 1.00 54.32  ? 359 LEU A CD1 1 
ATOM   6223 C  CD2 . LEU B 1 359 ? 149.180 145.847 124.024 1.00 54.32  ? 359 LEU A CD2 1 
ATOM   6224 N  N   . LEU B 1 360 ? 147.862 142.555 120.458 1.00 60.50  ? 360 LEU A N   1 
ATOM   6225 C  CA  . LEU B 1 360 ? 147.725 141.519 119.438 1.00 60.50  ? 360 LEU A CA  1 
ATOM   6226 C  C   . LEU B 1 360 ? 146.287 141.430 118.934 1.00 60.50  ? 360 LEU A C   1 
ATOM   6227 O  O   . LEU B 1 360 ? 146.003 140.703 117.978 1.00 60.50  ? 360 LEU A O   1 
ATOM   6228 C  CB  . LEU B 1 360 ? 148.198 140.164 119.971 1.00 60.50  ? 360 LEU A CB  1 
ATOM   6229 C  CG  . LEU B 1 360 ? 149.683 140.023 120.306 1.00 60.50  ? 360 LEU A CG  1 
ATOM   6230 C  CD1 . LEU B 1 360 ? 149.955 138.676 120.950 1.00 60.50  ? 360 LEU A CD1 1 
ATOM   6231 C  CD2 . LEU B 1 360 ? 150.534 140.205 119.061 1.00 60.50  ? 360 LEU A CD2 1 
ATOM   6232 N  N   . TRP B 1 361 ? 145.375 142.161 119.573 1.00 60.96  ? 361 TRP A N   1 
ATOM   6233 C  CA  . TRP B 1 361 ? 144.066 142.470 119.013 1.00 60.96  ? 361 TRP A CA  1 
ATOM   6234 C  C   . TRP B 1 361 ? 144.046 143.874 118.430 1.00 60.96  ? 361 TRP A C   1 
ATOM   6235 O  O   . TRP B 1 361 ? 143.699 144.062 117.261 1.00 60.96  ? 361 TRP A O   1 
ATOM   6236 C  CB  . TRP B 1 361 ? 142.970 142.327 120.077 1.00 60.96  ? 361 TRP A CB  1 
ATOM   6237 C  CG  . TRP B 1 361 ? 142.371 140.958 120.151 1.00 60.96  ? 361 TRP A CG  1 
ATOM   6238 C  CD1 . TRP B 1 361 ? 142.376 140.009 119.175 1.00 60.96  ? 361 TRP A CD1 1 
ATOM   6239 C  CD2 . TRP B 1 361 ? 141.656 140.393 121.256 1.00 60.96  ? 361 TRP A CD2 1 
ATOM   6240 N  NE1 . TRP B 1 361 ? 141.721 138.882 119.607 1.00 60.96  ? 361 TRP A NE1 1 
ATOM   6241 C  CE2 . TRP B 1 361 ? 141.268 139.094 120.881 1.00 60.96  ? 361 TRP A CE2 1 
ATOM   6242 C  CE3 . TRP B 1 361 ? 141.309 140.859 122.527 1.00 60.96  ? 361 TRP A CE3 1 
ATOM   6243 C  CZ2 . TRP B 1 361 ? 140.555 138.255 121.732 1.00 60.96  ? 361 TRP A CZ2 1 
ATOM   6244 C  CZ3 . TRP B 1 361 ? 140.601 140.024 123.369 1.00 60.96  ? 361 TRP A CZ3 1 
ATOM   6245 C  CH2 . TRP B 1 361 ? 140.231 138.739 122.968 1.00 60.96  ? 361 TRP A CH2 1 
ATOM   6246 N  N   . PHE B 1 362 ? 144.417 144.866 119.232 1.00 69.28  ? 362 PHE A N   1 
ATOM   6247 C  CA  . PHE B 1 362 ? 144.849 146.139 118.691 1.00 69.28  ? 362 PHE A CA  1 
ATOM   6248 C  C   . PHE B 1 362 ? 146.278 145.998 118.171 1.00 69.28  ? 362 PHE A C   1 
ATOM   6249 O  O   . PHE B 1 362 ? 146.975 145.021 118.455 1.00 69.28  ? 362 PHE A O   1 
ATOM   6250 C  CB  . PHE B 1 362 ? 144.760 147.240 119.748 1.00 69.28  ? 362 PHE A CB  1 
ATOM   6251 C  CG  . PHE B 1 362 ? 143.561 147.124 120.647 1.00 69.28  ? 362 PHE A CG  1 
ATOM   6252 C  CD1 . PHE B 1 362 ? 142.281 147.099 120.120 1.00 69.28  ? 362 PHE A CD1 1 
ATOM   6253 C  CD2 . PHE B 1 362 ? 143.715 147.052 122.021 1.00 69.28  ? 362 PHE A CD2 1 
ATOM   6254 C  CE1 . PHE B 1 362 ? 141.179 146.991 120.947 1.00 69.28  ? 362 PHE A CE1 1 
ATOM   6255 C  CE2 . PHE B 1 362 ? 142.617 146.945 122.851 1.00 69.28  ? 362 PHE A CE2 1 
ATOM   6256 C  CZ  . PHE B 1 362 ? 141.348 146.915 122.313 1.00 69.28  ? 362 PHE A CZ  1 
ATOM   6257 N  N   . SER B 1 363 ? 146.706 146.983 117.384 1.00 87.61  ? 363 SER A N   1 
ATOM   6258 C  CA  . SER B 1 363 ? 147.991 147.012 116.690 1.00 87.61  ? 363 SER A CA  1 
ATOM   6259 C  C   . SER B 1 363 ? 148.100 145.937 115.616 1.00 87.61  ? 363 SER A C   1 
ATOM   6260 O  O   . SER B 1 363 ? 149.153 145.828 114.975 1.00 87.61  ? 363 SER A O   1 
ATOM   6261 C  CB  . SER B 1 363 ? 149.185 146.880 117.648 1.00 87.61  ? 363 SER A CB  1 
ATOM   6262 O  OG  . SER B 1 363 ? 149.297 145.555 118.139 1.00 87.61  ? 363 SER A OG  1 
ATOM   6263 N  N   . ARG B 1 364 ? 147.057 145.136 115.396 1.00 88.25  ? 364 ARG A N   1 
ATOM   6264 C  CA  . ARG B 1 364 ? 147.066 144.179 114.290 1.00 88.25  ? 364 ARG A CA  1 
ATOM   6265 C  C   . ARG B 1 364 ? 146.679 144.871 112.987 1.00 88.25  ? 364 ARG A C   1 
ATOM   6266 O  O   . ARG B 1 364 ? 147.477 144.952 112.049 1.00 88.25  ? 364 ARG A O   1 
ATOM   6267 C  CB  . ARG B 1 364 ? 146.120 143.014 114.595 1.00 88.25  ? 364 ARG A CB  1 
ATOM   6268 C  CG  . ARG B 1 364 ? 146.530 141.700 113.963 1.00 88.25  ? 364 ARG A CG  1 
ATOM   6269 C  CD  . ARG B 1 364 ? 145.609 140.573 114.398 1.00 88.25  ? 364 ARG A CD  1 
ATOM   6270 N  NE  . ARG B 1 364 ? 144.219 140.824 114.035 1.00 88.25  ? 364 ARG A NE  1 
ATOM   6271 C  CZ  . ARG B 1 364 ? 143.754 140.849 112.794 1.00 88.25  ? 364 ARG A CZ  1 
ATOM   6272 N  NH1 . ARG B 1 364 ? 144.538 140.617 111.754 1.00 88.25  ? 364 ARG A NH1 1 
ATOM   6273 N  NH2 . ARG B 1 364 ? 142.465 141.106 112.590 1.00 88.25  ? 364 ARG A NH2 1 
ATOM   6274 N  N   . ASP B 1 365 ? 145.450 145.381 112.921 1.00 98.10  ? 365 ASP A N   1 
ATOM   6275 C  CA  . ASP B 1 365 ? 144.972 146.163 111.780 1.00 98.10  ? 365 ASP A CA  1 
ATOM   6276 C  C   . ASP B 1 365 ? 144.236 147.390 112.299 1.00 98.10  ? 365 ASP A C   1 
ATOM   6277 O  O   . ASP B 1 365 ? 143.011 147.500 112.176 1.00 98.10  ? 365 ASP A O   1 
ATOM   6278 C  CB  . ASP B 1 365 ? 144.068 145.320 110.879 1.00 98.10  ? 365 ASP A CB  1 
ATOM   6279 C  CG  . ASP B 1 365 ? 144.792 144.140 110.267 1.00 98.10  ? 365 ASP A CG  1 
ATOM   6280 O  OD1 . ASP B 1 365 ? 145.919 144.329 109.766 1.00 98.10  ? 365 ASP A OD1 1 
ATOM   6281 O  OD2 . ASP B 1 365 ? 144.232 143.025 110.289 1.00 98.10  ? 365 ASP A OD2 1 
ATOM   6282 N  N   . PRO B 1 366 ? 144.957 148.336 112.899 1.00 105.40 ? 366 PRO A N   1 
ATOM   6283 C  CA  . PRO B 1 366 ? 144.296 149.539 113.413 1.00 105.40 ? 366 PRO A CA  1 
ATOM   6284 C  C   . PRO B 1 366 ? 143.745 150.392 112.282 1.00 105.40 ? 366 PRO A C   1 
ATOM   6285 O  O   . PRO B 1 366 ? 144.295 150.437 111.179 1.00 105.40 ? 366 PRO A O   1 
ATOM   6286 C  CB  . PRO B 1 366 ? 145.411 150.270 114.172 1.00 105.40 ? 366 PRO A CB  1 
ATOM   6287 C  CG  . PRO B 1 366 ? 146.545 149.288 114.274 1.00 105.40 ? 366 PRO A CG  1 
ATOM   6288 C  CD  . PRO B 1 366 ? 146.413 148.386 113.097 1.00 105.40 ? 366 PRO A CD  1 
ATOM   6289 N  N   . GLY B 1 367 ? 142.635 151.071 112.572 1.00 110.76 ? 367 GLY A N   1 
ATOM   6290 C  CA  . GLY B 1 367 ? 141.996 151.889 111.554 1.00 110.76 ? 367 GLY A CA  1 
ATOM   6291 C  C   . GLY B 1 367 ? 142.837 153.083 111.140 1.00 110.76 ? 367 GLY A C   1 
ATOM   6292 O  O   . GLY B 1 367 ? 142.972 153.380 109.950 1.00 110.76 ? 367 GLY A O   1 
ATOM   6293 N  N   . PHE B 1 368 ? 143.415 153.784 112.116 1.00 119.37 ? 368 PHE A N   1 
ATOM   6294 C  CA  . PHE B 1 368 ? 144.155 155.014 111.852 1.00 119.37 ? 368 PHE A CA  1 
ATOM   6295 C  C   . PHE B 1 368 ? 145.656 154.775 111.714 1.00 119.37 ? 368 PHE A C   1 
ATOM   6296 O  O   . PHE B 1 368 ? 146.239 155.050 110.661 1.00 119.37 ? 368 PHE A O   1 
ATOM   6297 C  CB  . PHE B 1 368 ? 143.879 156.035 112.964 1.00 119.37 ? 368 PHE A CB  1 
ATOM   6298 N  N   . VAL B 1 369 ? 146.291 154.264 112.759 1.00 119.78 ? 369 VAL A N   1 
ATOM   6299 C  CA  . VAL B 1 369 ? 147.745 154.089 112.754 1.00 119.78 ? 369 VAL A CA  1 
ATOM   6300 C  C   . VAL B 1 369 ? 148.083 152.780 112.047 1.00 119.78 ? 369 VAL A C   1 
ATOM   6301 O  O   . VAL B 1 369 ? 147.531 151.731 112.410 1.00 119.78 ? 369 VAL A O   1 
ATOM   6302 C  CB  . VAL B 1 369 ? 148.291 154.101 114.178 1.00 119.78 ? 369 VAL A CB  1 
ATOM   6303 C  CG1 . VAL B 1 369 ? 149.812 154.021 114.166 1.00 119.78 ? 369 VAL A CG1 1 
ATOM   6304 C  CG2 . VAL B 1 369 ? 147.825 155.349 114.913 1.00 119.78 ? 369 VAL A CG2 1 
ATOM   6305 N  N   . PRO B 1 370 ? 148.966 152.793 111.047 1.00 119.60 ? 370 PRO A N   1 
ATOM   6306 C  CA  . PRO B 1 370 ? 149.348 151.539 110.380 1.00 119.60 ? 370 PRO A CA  1 
ATOM   6307 C  C   . PRO B 1 370 ? 150.136 150.644 111.326 1.00 119.60 ? 370 PRO A C   1 
ATOM   6308 O  O   . PRO B 1 370 ? 151.231 150.997 111.769 1.00 119.60 ? 370 PRO A O   1 
ATOM   6309 C  CB  . PRO B 1 370 ? 150.201 152.014 109.199 1.00 119.60 ? 370 PRO A CB  1 
ATOM   6310 C  CG  . PRO B 1 370 ? 150.765 153.319 109.654 1.00 119.60 ? 370 PRO A CG  1 
ATOM   6311 C  CD  . PRO B 1 370 ? 149.699 153.952 110.511 1.00 119.60 ? 370 PRO A CD  1 
ATOM   6312 N  N   . GLY B 1 371 ? 149.570 149.480 111.634 1.00 117.42 ? 371 GLY A N   1 
ATOM   6313 C  CA  . GLY B 1 371 ? 150.215 148.542 112.531 1.00 117.42 ? 371 GLY A CA  1 
ATOM   6314 C  C   . GLY B 1 371 ? 150.845 147.372 111.806 1.00 117.42 ? 371 GLY A C   1 
ATOM   6315 O  O   . GLY B 1 371 ? 150.141 146.486 111.312 1.00 117.42 ? 371 GLY A O   1 
ATOM   6316 N  N   . TRP B 1 372 ? 152.176 147.357 111.738 1.00 120.48 ? 372 TRP A N   1 
ATOM   6317 C  CA  . TRP B 1 372 ? 152.911 146.311 111.038 1.00 120.48 ? 372 TRP A CA  1 
ATOM   6318 C  C   . TRP B 1 372 ? 153.594 145.336 111.988 1.00 120.48 ? 372 TRP A C   1 
ATOM   6319 O  O   . TRP B 1 372 ? 154.290 144.423 111.525 1.00 120.48 ? 372 TRP A O   1 
ATOM   6320 C  CB  . TRP B 1 372 ? 153.945 146.930 110.093 1.00 120.48 ? 372 TRP A CB  1 
ATOM   6321 N  N   . SER B 1 373 ? 153.425 145.507 113.301 1.00 118.85 ? 373 SER A N   1 
ATOM   6322 C  CA  . SER B 1 373 ? 153.988 144.548 114.246 1.00 118.85 ? 373 SER A CA  1 
ATOM   6323 C  C   . SER B 1 373 ? 153.339 143.179 114.086 1.00 118.85 ? 373 SER A C   1 
ATOM   6324 O  O   . SER B 1 373 ? 154.021 142.148 114.136 1.00 118.85 ? 373 SER A O   1 
ATOM   6325 C  CB  . SER B 1 373 ? 153.824 145.061 115.677 1.00 118.85 ? 373 SER A CB  1 
ATOM   6326 O  OG  . SER B 1 373 ? 154.558 144.267 116.592 1.00 118.85 ? 373 SER A OG  1 
ATOM   6327 N  N   . ALA B 1 374 ? 152.026 143.150 113.892 1.00 108.19 ? 374 ALA A N   1 
ATOM   6328 C  CA  . ALA B 1 374 ? 151.290 141.928 113.615 1.00 108.19 ? 374 ALA A CA  1 
ATOM   6329 C  C   . ALA B 1 374 ? 150.775 141.954 112.182 1.00 108.19 ? 374 ALA A C   1 
ATOM   6330 O  O   . ALA B 1 374 ? 150.690 143.010 111.549 1.00 108.19 ? 374 ALA A O   1 
ATOM   6331 C  CB  . ALA B 1 374 ? 150.129 141.747 114.599 1.00 108.19 ? 374 ALA A CB  1 
ATOM   6332 N  N   . LEU B 1 375 ? 150.438 140.767 111.676 1.00 105.01 ? 375 LEU A N   1 
ATOM   6333 C  CA  . LEU B 1 375 ? 150.019 140.582 110.285 1.00 105.01 ? 375 LEU A CA  1 
ATOM   6334 C  C   . LEU B 1 375 ? 151.089 141.059 109.306 1.00 105.01 ? 375 LEU A C   1 
ATOM   6335 O  O   . LEU B 1 375 ? 150.782 141.546 108.216 1.00 105.01 ? 375 LEU A O   1 
ATOM   6336 C  CB  . LEU B 1 375 ? 148.679 141.270 110.002 1.00 105.01 ? 375 LEU A CB  1 
ATOM   6337 C  CG  . LEU B 1 375 ? 147.859 140.676 108.851 1.00 105.01 ? 375 LEU A CG  1 
ATOM   6338 C  CD1 . LEU B 1 375 ? 147.780 139.161 108.958 1.00 105.01 ? 375 LEU A CD1 1 
ATOM   6339 C  CD2 . LEU B 1 375 ? 146.468 141.282 108.803 1.00 105.01 ? 375 LEU A CD2 1 
ATOM   6340 N  N   . PHE B 1 376 ? 152.356 140.933 109.693 1.00 109.77 ? 376 PHE A N   1 
ATOM   6341 C  CA  . PHE B 1 376 ? 153.466 141.163 108.781 1.00 109.77 ? 376 PHE A CA  1 
ATOM   6342 C  C   . PHE B 1 376 ? 153.942 139.886 108.106 1.00 109.77 ? 376 PHE A C   1 
ATOM   6343 O  O   . PHE B 1 376 ? 154.802 139.953 107.221 1.00 109.77 ? 376 PHE A O   1 
ATOM   6344 C  CB  . PHE B 1 376 ? 154.636 141.817 109.523 1.00 109.77 ? 376 PHE A CB  1 
ATOM   6345 C  CG  . PHE B 1 376 ? 155.517 140.840 110.248 1.00 109.77 ? 376 PHE A CG  1 
ATOM   6346 C  CD1 . PHE B 1 376 ? 155.109 140.277 111.445 1.00 109.77 ? 376 PHE A CD1 1 
ATOM   6347 C  CD2 . PHE B 1 376 ? 156.754 140.486 109.734 1.00 109.77 ? 376 PHE A CD2 1 
ATOM   6348 C  CE1 . PHE B 1 376 ? 155.916 139.378 112.115 1.00 109.77 ? 376 PHE A CE1 1 
ATOM   6349 C  CE2 . PHE B 1 376 ? 157.565 139.586 110.399 1.00 109.77 ? 376 PHE A CE2 1 
ATOM   6350 C  CZ  . PHE B 1 376 ? 157.145 139.032 111.592 1.00 109.77 ? 376 PHE A CZ  1 
ATOM   6351 N  N   . SER B 1 377 ? 153.408 138.734 108.500 1.00 108.70 ? 377 SER A N   1 
ATOM   6352 C  CA  . SER B 1 377 ? 153.841 137.467 107.930 1.00 108.70 ? 377 SER A CA  1 
ATOM   6353 C  C   . SER B 1 377 ? 153.178 137.228 106.580 1.00 108.70 ? 377 SER A C   1 
ATOM   6354 O  O   . SER B 1 377 ? 151.988 137.499 106.395 1.00 108.70 ? 377 SER A O   1 
ATOM   6355 C  CB  . SER B 1 377 ? 153.515 136.320 108.885 1.00 108.70 ? 377 SER A CB  1 
ATOM   6356 O  OG  . SER B 1 377 ? 154.080 136.545 110.165 1.00 108.70 ? 377 SER A OG  1 
ATOM   6357 N  N   . GLU B 1 378 ? 153.961 136.712 105.630 1.00 110.13 ? 378 GLU A N   1 
ATOM   6358 C  CA  . GLU B 1 378 ? 153.419 136.367 104.322 1.00 110.13 ? 378 GLU A CA  1 
ATOM   6359 C  C   . GLU B 1 378 ? 152.553 135.116 104.369 1.00 110.13 ? 378 GLU A C   1 
ATOM   6360 O  O   . GLU B 1 378 ? 151.773 134.883 103.439 1.00 110.13 ? 378 GLU A O   1 
ATOM   6361 C  CB  . GLU B 1 378 ? 154.555 136.183 103.313 1.00 110.13 ? 378 GLU A CB  1 
ATOM   6362 C  CG  . GLU B 1 378 ? 155.634 135.202 103.750 1.00 110.13 ? 378 GLU A CG  1 
ATOM   6363 C  CD  . GLU B 1 378 ? 155.309 133.767 103.381 1.00 110.13 ? 378 GLU A CD  1 
ATOM   6364 O  OE1 . GLU B 1 378 ? 154.468 133.558 102.481 1.00 110.13 ? 378 GLU A OE1 1 
ATOM   6365 O  OE2 . GLU B 1 378 ? 155.896 132.848 103.989 1.00 110.13 ? 378 GLU A OE2 1 
ATOM   6366 N  N   . TYR B 1 379 ? 152.679 134.310 105.415 1.00 107.43 ? 379 TYR A N   1 
ATOM   6367 C  CA  . TYR B 1 379 ? 151.838 133.128 105.555 1.00 107.43 ? 379 TYR A CA  1 
ATOM   6368 C  C   . TYR B 1 379 ? 150.390 133.552 105.773 1.00 107.43 ? 379 TYR A C   1 
ATOM   6369 O  O   . TYR B 1 379 ? 150.126 134.445 106.586 1.00 107.43 ? 379 TYR A O   1 
ATOM   6370 C  CB  . TYR B 1 379 ? 152.310 132.256 106.719 1.00 107.43 ? 379 TYR A CB  1 
ATOM   6371 C  CG  . TYR B 1 379 ? 153.803 132.008 106.764 1.00 107.43 ? 379 TYR A CG  1 
ATOM   6372 C  CD1 . TYR B 1 379 ? 154.341 130.820 106.286 1.00 107.43 ? 379 TYR A CD1 1 
ATOM   6373 C  CD2 . TYR B 1 379 ? 154.671 132.947 107.307 1.00 107.43 ? 379 TYR A CD2 1 
ATOM   6374 C  CE1 . TYR B 1 379 ? 155.701 130.583 106.329 1.00 107.43 ? 379 TYR A CE1 1 
ATOM   6375 C  CE2 . TYR B 1 379 ? 156.033 132.719 107.354 1.00 107.43 ? 379 TYR A CE2 1 
ATOM   6376 C  CZ  . TYR B 1 379 ? 156.542 131.535 106.864 1.00 107.43 ? 379 TYR A CZ  1 
ATOM   6377 O  OH  . TYR B 1 379 ? 157.898 131.303 106.910 1.00 107.43 ? 379 TYR A OH  1 
ATOM   6378 N  N   . PRO B 1 380 ? 149.432 132.948 105.078 1.00 101.56 ? 380 PRO A N   1 
ATOM   6379 C  CA  . PRO B 1 380 ? 148.032 133.333 105.265 1.00 101.56 ? 380 PRO A CA  1 
ATOM   6380 C  C   . PRO B 1 380 ? 147.418 132.649 106.474 1.00 101.56 ? 380 PRO A C   1 
ATOM   6381 O  O   . PRO B 1 380 ? 147.643 131.466 106.738 1.00 101.56 ? 380 PRO A O   1 
ATOM   6382 C  CB  . PRO B 1 380 ? 147.363 132.869 103.966 1.00 101.56 ? 380 PRO A CB  1 
ATOM   6383 C  CG  . PRO B 1 380 ? 148.241 131.762 103.445 1.00 101.56 ? 380 PRO A CG  1 
ATOM   6384 C  CD  . PRO B 1 380 ? 149.582 131.827 104.135 1.00 101.56 ? 380 PRO A CD  1 
ATOM   6385 N  N   . GLY B 1 381 ? 146.632 133.425 107.219 1.00 93.39  ? 381 GLY A N   1 
ATOM   6386 C  CA  . GLY B 1 381 ? 145.989 132.934 108.417 1.00 93.39  ? 381 GLY A CA  1 
ATOM   6387 C  C   . GLY B 1 381 ? 146.873 132.881 109.641 1.00 93.39  ? 381 GLY A C   1 
ATOM   6388 O  O   . GLY B 1 381 ? 146.397 132.477 110.709 1.00 93.39  ? 381 GLY A O   1 
ATOM   6389 N  N   . PHE B 1 382 ? 148.143 133.273 109.525 1.00 95.87  ? 382 PHE A N   1 
ATOM   6390 C  CA  . PHE B 1 382 ? 149.036 133.260 110.679 1.00 95.87  ? 382 PHE A CA  1 
ATOM   6391 C  C   . PHE B 1 382 ? 148.561 134.219 111.761 1.00 95.87  ? 382 PHE A C   1 
ATOM   6392 O  O   . PHE B 1 382 ? 148.586 133.886 112.951 1.00 95.87  ? 382 PHE A O   1 
ATOM   6393 C  CB  . PHE B 1 382 ? 150.458 133.608 110.241 1.00 95.87  ? 382 PHE A CB  1 
ATOM   6394 C  CG  . PHE B 1 382 ? 151.444 133.668 111.371 1.00 95.87  ? 382 PHE A CG  1 
ATOM   6395 C  CD1 . PHE B 1 382 ? 151.906 132.508 111.969 1.00 95.87  ? 382 PHE A CD1 1 
ATOM   6396 C  CD2 . PHE B 1 382 ? 151.918 134.887 111.828 1.00 95.87  ? 382 PHE A CD2 1 
ATOM   6397 C  CE1 . PHE B 1 382 ? 152.816 132.563 113.009 1.00 95.87  ? 382 PHE A CE1 1 
ATOM   6398 C  CE2 . PHE B 1 382 ? 152.829 134.949 112.865 1.00 95.87  ? 382 PHE A CE2 1 
ATOM   6399 C  CZ  . PHE B 1 382 ? 153.279 133.786 113.457 1.00 95.87  ? 382 PHE A CZ  1 
ATOM   6400 N  N   . ALA B 1 383 ? 148.125 135.413 111.370 1.00 90.84  ? 383 ALA A N   1 
ATOM   6401 C  CA  . ALA B 1 383 ? 147.681 136.443 112.306 1.00 90.84  ? 383 ALA A CA  1 
ATOM   6402 C  C   . ALA B 1 383 ? 146.230 136.790 111.989 1.00 90.84  ? 383 ALA A C   1 
ATOM   6403 O  O   . ALA B 1 383 ? 145.946 137.462 110.993 1.00 90.84  ? 383 ALA A O   1 
ATOM   6404 C  CB  . ALA B 1 383 ? 148.577 137.675 112.233 1.00 90.84  ? 383 ALA A CB  1 
ATOM   6405 N  N   . THR B 1 384 ? 145.317 136.325 112.837 1.00 78.35  ? 384 THR A N   1 
ATOM   6406 C  CA  . THR B 1 384 ? 143.907 136.663 112.718 1.00 78.35  ? 384 THR A CA  1 
ATOM   6407 C  C   . THR B 1 384 ? 143.309 136.698 114.115 1.00 78.35  ? 384 THR A C   1 
ATOM   6408 O  O   . THR B 1 384 ? 143.898 136.195 115.074 1.00 78.35  ? 384 THR A O   1 
ATOM   6409 C  CB  . THR B 1 384 ? 143.152 135.672 111.822 1.00 78.35  ? 384 THR A CB  1 
ATOM   6410 O  OG1 . THR B 1 384 ? 141.807 136.126 111.633 1.00 78.35  ? 384 THR A OG1 1 
ATOM   6411 C  CG2 . THR B 1 384 ? 143.130 134.293 112.449 1.00 78.35  ? 384 THR A CG2 1 
ATOM   6412 N  N   . ASP B 1 385 ? 142.129 137.313 114.222 1.00 73.20  ? 385 ASP A N   1 
ATOM   6413 C  CA  . ASP B 1 385 ? 141.518 137.515 115.532 1.00 73.20  ? 385 ASP A CA  1 
ATOM   6414 C  C   . ASP B 1 385 ? 141.202 136.190 116.216 1.00 73.20  ? 385 ASP A C   1 
ATOM   6415 O  O   . ASP B 1 385 ? 141.434 136.037 117.419 1.00 73.20  ? 385 ASP A O   1 
ATOM   6416 C  CB  . ASP B 1 385 ? 140.257 138.365 115.396 1.00 73.20  ? 385 ASP A CB  1 
ATOM   6417 C  CG  . ASP B 1 385 ? 140.561 139.797 115.011 1.00 73.20  ? 385 ASP A CG  1 
ATOM   6418 O  OD1 . ASP B 1 385 ? 141.651 140.292 115.369 1.00 73.20  ? 385 ASP A OD1 1 
ATOM   6419 O  OD2 . ASP B 1 385 ? 139.713 140.429 114.348 1.00 73.20  ? 385 ASP A OD2 1 
ATOM   6420 N  N   . SER B 1 386 ? 140.672 135.220 115.468 1.00 70.53  ? 386 SER A N   1 
ATOM   6421 C  CA  . SER B 1 386 ? 140.307 133.940 116.068 1.00 70.53  ? 386 SER A CA  1 
ATOM   6422 C  C   . SER B 1 386 ? 141.530 133.198 116.591 1.00 70.53  ? 386 SER A C   1 
ATOM   6423 O  O   . SER B 1 386 ? 141.500 132.631 117.692 1.00 70.53  ? 386 SER A O   1 
ATOM   6424 C  CB  . SER B 1 386 ? 139.561 133.082 115.049 1.00 70.53  ? 386 SER A CB  1 
ATOM   6425 O  OG  . SER B 1 386 ? 140.427 132.659 114.011 1.00 70.53  ? 386 SER A OG  1 
ATOM   6426 N  N   . THR B 1 387 ? 142.613 133.181 115.811 1.00 67.80  ? 387 THR A N   1 
ATOM   6427 C  CA  . THR B 1 387 ? 143.825 132.493 116.239 1.00 67.80  ? 387 THR A CA  1 
ATOM   6428 C  C   . THR B 1 387 ? 144.422 133.146 117.478 1.00 67.80  ? 387 THR A C   1 
ATOM   6429 O  O   . THR B 1 387 ? 144.683 132.474 118.480 1.00 67.80  ? 387 THR A O   1 
ATOM   6430 C  CB  . THR B 1 387 ? 144.849 132.474 115.106 1.00 67.80  ? 387 THR A CB  1 
ATOM   6431 O  OG1 . THR B 1 387 ? 144.351 131.683 114.021 1.00 67.80  ? 387 THR A OG1 1 
ATOM   6432 C  CG2 . THR B 1 387 ? 146.161 131.894 115.591 1.00 67.80  ? 387 THR A CG2 1 
ATOM   6433 N  N   . VAL B 1 388 ? 144.639 134.463 117.432 1.00 62.79  ? 388 VAL A N   1 
ATOM   6434 C  CA  . VAL B 1 388 ? 145.228 135.144 118.577 1.00 62.79  ? 388 VAL A CA  1 
ATOM   6435 C  C   . VAL B 1 388 ? 144.292 135.114 119.776 1.00 62.79  ? 388 VAL A C   1 
ATOM   6436 O  O   . VAL B 1 388 ? 144.740 135.277 120.916 1.00 62.79  ? 388 VAL A O   1 
ATOM   6437 C  CB  . VAL B 1 388 ? 145.610 136.590 118.209 1.00 62.79  ? 388 VAL A CB  1 
ATOM   6438 C  CG1 . VAL B 1 388 ? 144.370 137.444 118.028 1.00 62.79  ? 388 VAL A CG1 1 
ATOM   6439 C  CG2 . VAL B 1 388 ? 146.526 137.180 119.261 1.00 62.79  ? 388 VAL A CG2 1 
ATOM   6440 N  N   . ALA B 1 389 ? 142.998 134.891 119.551 1.00 61.07  ? 389 ALA A N   1 
ATOM   6441 C  CA  . ALA B 1 389 ? 142.066 134.759 120.661 1.00 61.07  ? 389 ALA A CA  1 
ATOM   6442 C  C   . ALA B 1 389 ? 142.210 133.398 121.327 1.00 61.07  ? 389 ALA A C   1 
ATOM   6443 O  O   . ALA B 1 389 ? 142.569 133.305 122.505 1.00 61.07  ? 389 ALA A O   1 
ATOM   6444 C  CB  . ALA B 1 389 ? 140.634 134.975 120.172 1.00 61.07  ? 389 ALA A CB  1 
ATOM   6445 N  N   . LEU B 1 390 ? 141.959 132.322 120.580 1.00 56.63  ? 390 LEU A N   1 
ATOM   6446 C  CA  . LEU B 1 390 ? 141.924 131.006 121.213 1.00 56.63  ? 390 LEU A CA  1 
ATOM   6447 C  C   . LEU B 1 390 ? 143.301 130.460 121.565 1.00 56.63  ? 390 LEU A C   1 
ATOM   6448 O  O   . LEU B 1 390 ? 143.425 129.753 122.569 1.00 56.63  ? 390 LEU A O   1 
ATOM   6449 C  CB  . LEU B 1 390 ? 141.181 129.990 120.350 1.00 56.63  ? 390 LEU A CB  1 
ATOM   6450 C  CG  . LEU B 1 390 ? 139.690 130.231 120.157 1.00 56.63  ? 390 LEU A CG  1 
ATOM   6451 C  CD1 . LEU B 1 390 ? 139.116 129.229 119.184 1.00 56.63  ? 390 LEU A CD1 1 
ATOM   6452 C  CD2 . LEU B 1 390 ? 138.994 130.136 121.493 1.00 56.63  ? 390 LEU A CD2 1 
ATOM   6453 N  N   . LEU B 1 391 ? 144.341 130.759 120.783 1.00 52.08  ? 391 LEU A N   1 
ATOM   6454 C  CA  . LEU B 1 391 ? 145.666 130.249 121.114 1.00 52.08  ? 391 LEU A CA  1 
ATOM   6455 C  C   . LEU B 1 391 ? 146.099 130.700 122.503 1.00 52.08  ? 391 LEU A C   1 
ATOM   6456 O  O   . LEU B 1 391 ? 146.930 130.042 123.140 1.00 52.08  ? 391 LEU A O   1 
ATOM   6457 C  CB  . LEU B 1 391 ? 146.671 130.703 120.052 1.00 52.08  ? 391 LEU A CB  1 
ATOM   6458 C  CG  . LEU B 1 391 ? 148.167 130.509 120.295 1.00 52.08  ? 391 LEU A CG  1 
ATOM   6459 C  CD1 . LEU B 1 391 ? 148.493 129.037 120.476 1.00 52.08  ? 391 LEU A CD1 1 
ATOM   6460 C  CD2 . LEU B 1 391 ? 148.974 131.105 119.153 1.00 52.08  ? 391 LEU A CD2 1 
ATOM   6461 N  N   . ILE B 1 392 ? 145.534 131.802 122.994 1.00 50.19  ? 392 ILE A N   1 
ATOM   6462 C  CA  . ILE B 1 392 ? 145.812 132.294 124.338 1.00 50.19  ? 392 ILE A CA  1 
ATOM   6463 C  C   . ILE B 1 392 ? 144.702 131.854 125.287 1.00 50.19  ? 392 ILE A C   1 
ATOM   6464 O  O   . ILE B 1 392 ? 144.953 131.577 126.465 1.00 50.19  ? 392 ILE A O   1 
ATOM   6465 C  CB  . ILE B 1 392 ? 145.969 133.825 124.339 1.00 50.19  ? 392 ILE A CB  1 
ATOM   6466 C  CG1 . ILE B 1 392 ? 147.042 134.255 123.338 1.00 50.19  ? 392 ILE A CG1 1 
ATOM   6467 C  CG2 . ILE B 1 392 ? 146.336 134.323 125.722 1.00 50.19  ? 392 ILE A CG2 1 
ATOM   6468 C  CD1 . ILE B 1 392 ? 148.418 133.719 123.645 1.00 50.19  ? 392 ILE A CD1 1 
ATOM   6469 N  N   . GLY B 1 393 ? 143.467 131.781 124.784 1.00 50.31  ? 393 GLY A N   1 
ATOM   6470 C  CA  . GLY B 1 393 ? 142.347 131.430 125.642 1.00 50.31  ? 393 GLY A CA  1 
ATOM   6471 C  C   . GLY B 1 393 ? 142.406 130.007 126.161 1.00 50.31  ? 393 GLY A C   1 
ATOM   6472 O  O   . GLY B 1 393 ? 142.156 129.761 127.343 1.00 50.31  ? 393 GLY A O   1 
ATOM   6473 N  N   . LEU B 1 394 ? 142.734 129.052 125.291 1.00 50.67  ? 394 LEU A N   1 
ATOM   6474 C  CA  . LEU B 1 394 ? 142.840 127.661 125.719 1.00 50.67  ? 394 LEU A CA  1 
ATOM   6475 C  C   . LEU B 1 394 ? 143.994 127.433 126.683 1.00 50.67  ? 394 LEU A C   1 
ATOM   6476 O  O   . LEU B 1 394 ? 144.041 126.382 127.330 1.00 50.67  ? 394 LEU A O   1 
ATOM   6477 C  CB  . LEU B 1 394 ? 142.966 126.729 124.513 1.00 50.67  ? 394 LEU A CB  1 
ATOM   6478 C  CG  . LEU B 1 394 ? 141.684 126.408 123.736 1.00 50.67  ? 394 LEU A CG  1 
ATOM   6479 C  CD1 . LEU B 1 394 ? 141.167 127.577 122.935 1.00 50.67  ? 394 LEU A CD1 1 
ATOM   6480 C  CD2 . LEU B 1 394 ? 141.923 125.223 122.819 1.00 50.67  ? 394 LEU A CD2 1 
ATOM   6481 N  N   . LEU B 1 395 ? 144.925 128.383 126.794 1.00 47.07  ? 395 LEU A N   1 
ATOM   6482 C  CA  . LEU B 1 395 ? 145.915 128.308 127.859 1.00 47.07  ? 395 LEU A CA  1 
ATOM   6483 C  C   . LEU B 1 395 ? 145.270 128.397 129.234 1.00 47.07  ? 395 LEU A C   1 
ATOM   6484 O  O   . LEU B 1 395 ? 145.848 127.912 130.212 1.00 47.07  ? 395 LEU A O   1 
ATOM   6485 C  CB  . LEU B 1 395 ? 146.956 129.414 127.694 1.00 47.07  ? 395 LEU A CB  1 
ATOM   6486 C  CG  . LEU B 1 395 ? 148.301 128.990 127.105 1.00 47.07  ? 395 LEU A CG  1 
ATOM   6487 C  CD1 . LEU B 1 395 ? 148.114 128.393 125.725 1.00 47.07  ? 395 LEU A CD1 1 
ATOM   6488 C  CD2 . LEU B 1 395 ? 149.252 130.171 127.052 1.00 47.07  ? 395 LEU A CD2 1 
ATOM   6489 N  N   . PHE B 1 396 ? 144.086 129.004 129.332 1.00 46.45  ? 396 PHE A N   1 
ATOM   6490 C  CA  . PHE B 1 396 ? 143.338 129.010 130.581 1.00 46.45  ? 396 PHE A CA  1 
ATOM   6491 C  C   . PHE B 1 396 ? 142.831 127.630 130.965 1.00 46.45  ? 396 PHE A C   1 
ATOM   6492 O  O   . PHE B 1 396 ? 142.406 127.447 132.108 1.00 46.45  ? 396 PHE A O   1 
ATOM   6493 C  CB  . PHE B 1 396 ? 142.149 129.965 130.488 1.00 46.45  ? 396 PHE A CB  1 
ATOM   6494 C  CG  . PHE B 1 396 ? 142.526 131.414 130.541 1.00 46.45  ? 396 PHE A CG  1 
ATOM   6495 C  CD1 . PHE B 1 396 ? 143.148 131.942 131.655 1.00 46.45  ? 396 PHE A CD1 1 
ATOM   6496 C  CD2 . PHE B 1 396 ? 142.256 132.251 129.474 1.00 46.45  ? 396 PHE A CD2 1 
ATOM   6497 C  CE1 . PHE B 1 396 ? 143.489 133.275 131.705 1.00 46.45  ? 396 PHE A CE1 1 
ATOM   6498 C  CE2 . PHE B 1 396 ? 142.597 133.583 129.519 1.00 46.45  ? 396 PHE A CE2 1 
ATOM   6499 C  CZ  . PHE B 1 396 ? 143.215 134.095 130.634 1.00 46.45  ? 396 PHE A CZ  1 
ATOM   6500 N  N   . PHE B 1 397 ? 142.843 126.670 130.042 1.00 46.67  ? 397 PHE A N   1 
ATOM   6501 C  CA  . PHE B 1 397 ? 142.356 125.325 130.310 1.00 46.67  ? 397 PHE A CA  1 
ATOM   6502 C  C   . PHE B 1 397 ? 143.452 124.352 130.717 1.00 46.67  ? 397 PHE A C   1 
ATOM   6503 O  O   . PHE B 1 397 ? 143.145 123.193 131.012 1.00 46.67  ? 397 PHE A O   1 
ATOM   6504 C  CB  . PHE B 1 397 ? 141.631 124.767 129.081 1.00 46.67  ? 397 PHE A CB  1 
ATOM   6505 C  CG  . PHE B 1 397 ? 140.199 125.194 128.976 1.00 46.67  ? 397 PHE A CG  1 
ATOM   6506 C  CD1 . PHE B 1 397 ? 139.229 124.598 129.758 1.00 46.67  ? 397 PHE A CD1 1 
ATOM   6507 C  CD2 . PHE B 1 397 ? 139.821 126.181 128.088 1.00 46.67  ? 397 PHE A CD2 1 
ATOM   6508 C  CE1 . PHE B 1 397 ? 137.912 124.984 129.662 1.00 46.67  ? 397 PHE A CE1 1 
ATOM   6509 C  CE2 . PHE B 1 397 ? 138.506 126.570 127.987 1.00 46.67  ? 397 PHE A CE2 1 
ATOM   6510 C  CZ  . PHE B 1 397 ? 137.550 125.972 128.776 1.00 46.67  ? 397 PHE A CZ  1 
ATOM   6511 N  N   . LEU B 1 398 ? 144.715 124.780 130.733 1.00 51.08  ? 398 LEU A N   1 
ATOM   6512 C  CA  . LEU B 1 398 ? 145.814 123.887 131.065 1.00 51.08  ? 398 LEU A CA  1 
ATOM   6513 C  C   . LEU B 1 398 ? 146.834 124.471 132.032 1.00 51.08  ? 398 LEU A C   1 
ATOM   6514 O  O   . LEU B 1 398 ? 147.660 123.711 132.548 1.00 51.08  ? 398 LEU A O   1 
ATOM   6515 C  CB  . LEU B 1 398 ? 146.532 123.426 129.784 1.00 51.08  ? 398 LEU A CB  1 
ATOM   6516 C  CG  . LEU B 1 398 ? 147.192 124.448 128.853 1.00 51.08  ? 398 LEU A CG  1 
ATOM   6517 C  CD1 . LEU B 1 398 ? 148.597 124.822 129.295 1.00 51.08  ? 398 LEU A CD1 1 
ATOM   6518 C  CD2 . LEU B 1 398 ? 147.207 123.924 127.427 1.00 51.08  ? 398 LEU A CD2 1 
ATOM   6519 N  N   . ILE B 1 399 ? 146.813 125.771 132.290 1.00 53.48  ? 399 ILE A N   1 
ATOM   6520 C  CA  . ILE B 1 399 ? 147.759 126.356 133.247 1.00 53.48  ? 399 ILE A CA  1 
ATOM   6521 C  C   . ILE B 1 399 ? 147.433 125.846 134.647 1.00 53.48  ? 399 ILE A C   1 
ATOM   6522 O  O   . ILE B 1 399 ? 146.261 125.889 135.061 1.00 53.48  ? 399 ILE A O   1 
ATOM   6523 C  CB  . ILE B 1 399 ? 147.701 127.883 133.187 1.00 53.48  ? 399 ILE A CB  1 
ATOM   6524 C  CG1 . ILE B 1 399 ? 148.442 128.394 131.952 1.00 53.48  ? 399 ILE A CG1 1 
ATOM   6525 C  CG2 . ILE B 1 399 ? 148.299 128.491 134.441 1.00 53.48  ? 399 ILE A CG2 1 
ATOM   6526 C  CD1 . ILE B 1 399 ? 149.932 128.164 131.999 1.00 53.48  ? 399 ILE A CD1 1 
ATOM   6527 N  N   . PRO B 1 400 ? 148.413 125.350 135.405 1.00 60.91  ? 400 PRO A N   1 
ATOM   6528 C  CA  . PRO B 1 400 ? 148.130 124.813 136.745 1.00 60.91  ? 400 PRO A CA  1 
ATOM   6529 C  C   . PRO B 1 400 ? 147.889 125.936 137.743 1.00 60.91  ? 400 PRO A C   1 
ATOM   6530 O  O   . PRO B 1 400 ? 148.774 126.755 138.000 1.00 60.91  ? 400 PRO A O   1 
ATOM   6531 C  CB  . PRO B 1 400 ? 149.400 124.023 137.083 1.00 60.91  ? 400 PRO A CB  1 
ATOM   6532 C  CG  . PRO B 1 400 ? 150.471 124.691 136.296 1.00 60.91  ? 400 PRO A CG  1 
ATOM   6533 C  CD  . PRO B 1 400 ? 149.830 125.198 135.032 1.00 60.91  ? 400 PRO A CD  1 
ATOM   6534 N  N   . ALA B 1 401 ? 146.684 125.971 138.312 1.00 63.58  ? 401 ALA A N   1 
ATOM   6535 C  CA  . ALA B 1 401 ? 146.317 126.988 139.292 1.00 63.58  ? 401 ALA A CA  1 
ATOM   6536 C  C   . ALA B 1 401 ? 146.394 126.464 140.721 1.00 63.58  ? 401 ALA A C   1 
ATOM   6537 O  O   . ALA B 1 401 ? 147.142 126.999 141.544 1.00 63.58  ? 401 ALA A O   1 
ATOM   6538 C  CB  . ALA B 1 401 ? 144.907 127.512 139.001 1.00 63.58  ? 401 ALA A CB  1 
ATOM   6539 N  N   . LYS B 1 402 ? 145.635 125.418 141.029 1.00 68.45  ? 402 LYS A N   1 
ATOM   6540 C  CA  . LYS B 1 402 ? 145.547 124.875 142.377 1.00 68.45  ? 402 LYS A CA  1 
ATOM   6541 C  C   . LYS B 1 402 ? 145.915 123.401 142.351 1.00 68.45  ? 402 LYS A C   1 
ATOM   6542 O  O   . LYS B 1 402 ? 145.350 122.630 141.569 1.00 68.45  ? 402 LYS A O   1 
ATOM   6543 C  CB  . LYS B 1 402 ? 144.140 125.062 142.949 1.00 68.45  ? 402 LYS A CB  1 
ATOM   6544 C  CG  . LYS B 1 402 ? 144.016 124.730 144.425 1.00 68.45  ? 402 LYS A CG  1 
ATOM   6545 C  CD  . LYS B 1 402 ? 142.852 125.476 145.056 1.00 68.45  ? 402 LYS A CD  1 
ATOM   6546 C  CE  . LYS B 1 402 ? 142.994 126.978 144.870 1.00 68.45  ? 402 LYS A CE  1 
ATOM   6547 N  NZ  . LYS B 1 402 ? 142.029 127.737 145.710 1.00 68.45  ? 402 LYS A NZ  1 
ATOM   6548 N  N   . THR B 1 403 ? 146.855 123.012 143.207 1.00 79.25  ? 403 THR A N   1 
ATOM   6549 C  CA  . THR B 1 403 ? 147.270 121.622 143.296 1.00 79.25  ? 403 THR A CA  1 
ATOM   6550 C  C   . THR B 1 403 ? 146.247 120.819 144.098 1.00 79.25  ? 403 THR A C   1 
ATOM   6551 O  O   . THR B 1 403 ? 145.222 121.339 144.548 1.00 79.25  ? 403 THR A O   1 
ATOM   6552 C  CB  . THR B 1 403 ? 148.658 121.519 143.924 1.00 79.25  ? 403 THR A CB  1 
ATOM   6553 O  OG1 . THR B 1 403 ? 149.040 120.141 144.014 1.00 79.25  ? 403 THR A OG1 1 
ATOM   6554 C  CG2 . THR B 1 403 ? 148.657 122.130 145.315 1.00 79.25  ? 403 THR A CG2 1 
ATOM   6555 N  N   . LEU B 1 404 ? 146.534 119.531 144.273 1.00 84.34  ? 404 LEU A N   1 
ATOM   6556 C  CA  . LEU B 1 404 ? 145.677 118.622 145.032 1.00 84.34  ? 404 LEU A CA  1 
ATOM   6557 C  C   . LEU B 1 404 ? 144.250 118.602 144.488 1.00 84.34  ? 404 LEU A C   1 
ATOM   6558 O  O   . LEU B 1 404 ? 143.854 117.668 143.790 1.00 84.34  ? 404 LEU A O   1 
ATOM   6559 C  CB  . LEU B 1 404 ? 145.670 119.004 146.516 1.00 84.34  ? 404 LEU A CB  1 
ATOM   6560 C  CG  . LEU B 1 404 ? 147.012 118.913 147.245 1.00 84.34  ? 404 LEU A CG  1 
ATOM   6561 C  CD1 . LEU B 1 404 ? 146.887 119.433 148.669 1.00 84.34  ? 404 LEU A CD1 1 
ATOM   6562 C  CD2 . LEU B 1 404 ? 147.531 117.485 147.235 1.00 84.34  ? 404 LEU A CD2 1 
ATOM   6563 N  N   . GLU B 1 412 ? 145.080 112.134 152.594 1.00 99.84  ? 412 GLU A N   1 
ATOM   6564 C  CA  . GLU B 1 412 ? 145.735 113.431 152.472 1.00 99.84  ? 412 GLU A CA  1 
ATOM   6565 C  C   . GLU B 1 412 ? 146.401 113.585 151.108 1.00 99.84  ? 412 GLU A C   1 
ATOM   6566 O  O   . GLU B 1 412 ? 146.996 114.621 150.811 1.00 99.84  ? 412 GLU A O   1 
ATOM   6567 C  CB  . GLU B 1 412 ? 146.768 113.617 153.587 1.00 99.84  ? 412 GLU A CB  1 
ATOM   6568 C  CG  . GLU B 1 412 ? 148.033 112.791 153.411 1.00 99.84  ? 412 GLU A CG  1 
ATOM   6569 C  CD  . GLU B 1 412 ? 147.957 111.449 154.114 1.00 99.84  ? 412 GLU A CD  1 
ATOM   6570 O  OE1 . GLU B 1 412 ? 147.039 111.258 154.939 1.00 99.84  ? 412 GLU A OE1 1 
ATOM   6571 O  OE2 . GLU B 1 412 ? 148.817 110.584 153.843 1.00 99.84  ? 412 GLU A OE2 1 
ATOM   6572 N  N   . ILE B 1 413 ? 146.299 112.542 150.281 1.00 97.91  ? 413 ILE A N   1 
ATOM   6573 C  CA  . ILE B 1 413 ? 146.899 112.590 148.951 1.00 97.91  ? 413 ILE A CA  1 
ATOM   6574 C  C   . ILE B 1 413 ? 146.137 113.555 148.050 1.00 97.91  ? 413 ILE A C   1 
ATOM   6575 O  O   . ILE B 1 413 ? 146.743 114.334 147.304 1.00 97.91  ? 413 ILE A O   1 
ATOM   6576 C  CB  . ILE B 1 413 ? 146.970 111.176 148.346 1.00 97.91  ? 413 ILE A CB  1 
ATOM   6577 C  CG1 . ILE B 1 413 ? 145.615 110.472 148.450 1.00 97.91  ? 413 ILE A CG1 1 
ATOM   6578 C  CG2 . ILE B 1 413 ? 148.043 110.354 149.042 1.00 97.91  ? 413 ILE A CG2 1 
ATOM   6579 C  CD1 . ILE B 1 413 ? 145.550 109.158 147.702 1.00 97.91  ? 413 ILE A CD1 1 
ATOM   6580 N  N   . VAL B 1 414 ? 144.803 113.520 148.106 1.00 97.05  ? 414 VAL A N   1 
ATOM   6581 C  CA  . VAL B 1 414 ? 143.923 114.357 147.292 1.00 97.05  ? 414 VAL A CA  1 
ATOM   6582 C  C   . VAL B 1 414 ? 144.254 114.121 145.819 1.00 97.05  ? 414 VAL A C   1 
ATOM   6583 O  O   . VAL B 1 414 ? 144.246 115.050 145.003 1.00 97.05  ? 414 VAL A O   1 
ATOM   6584 C  CB  . VAL B 1 414 ? 144.040 115.844 147.689 1.00 97.05  ? 414 VAL A CB  1 
ATOM   6585 C  CG1 . VAL B 1 414 ? 142.905 116.671 147.082 1.00 97.05  ? 414 VAL A CG1 1 
ATOM   6586 C  CG2 . VAL B 1 414 ? 144.052 115.991 149.204 1.00 97.05  ? 414 VAL A CG2 1 
ATOM   6587 N  N   . ALA B 1 415 ? 144.601 112.874 145.489 1.00 95.50  ? 415 ALA A N   1 
ATOM   6588 C  CA  . ALA B 1 415 ? 144.835 112.410 144.122 1.00 95.50  ? 415 ALA A CA  1 
ATOM   6589 C  C   . ALA B 1 415 ? 146.071 113.039 143.488 1.00 95.50  ? 415 ALA A C   1 
ATOM   6590 O  O   . ALA B 1 415 ? 146.471 112.643 142.388 1.00 95.50  ? 415 ALA A O   1 
ATOM   6591 C  CB  . ALA B 1 415 ? 143.605 112.670 143.246 1.00 95.50  ? 415 ALA A CB  1 
ATOM   6592 N  N   . PHE B 1 416 ? 146.693 113.990 144.183 1.00 94.12  ? 416 PHE A N   1 
ATOM   6593 C  CA  . PHE B 1 416 ? 147.912 114.664 143.734 1.00 94.12  ? 416 PHE A CA  1 
ATOM   6594 C  C   . PHE B 1 416 ? 147.810 115.102 142.272 1.00 94.12  ? 416 PHE A C   1 
ATOM   6595 O  O   . PHE B 1 416 ? 148.597 114.702 141.412 1.00 94.12  ? 416 PHE A O   1 
ATOM   6596 C  CB  . PHE B 1 416 ? 149.135 113.774 143.963 1.00 94.12  ? 416 PHE A CB  1 
ATOM   6597 C  CG  . PHE B 1 416 ? 149.602 113.748 145.390 1.00 94.12  ? 416 PHE A CG  1 
ATOM   6598 C  CD1 . PHE B 1 416 ? 149.798 114.928 146.089 1.00 94.12  ? 416 PHE A CD1 1 
ATOM   6599 C  CD2 . PHE B 1 416 ? 149.845 112.546 146.034 1.00 94.12  ? 416 PHE A CD2 1 
ATOM   6600 C  CE1 . PHE B 1 416 ? 150.228 114.910 147.403 1.00 94.12  ? 416 PHE A CE1 1 
ATOM   6601 C  CE2 . PHE B 1 416 ? 150.275 112.522 147.348 1.00 94.12  ? 416 PHE A CE2 1 
ATOM   6602 C  CZ  . PHE B 1 416 ? 150.466 113.706 148.033 1.00 94.12  ? 416 PHE A CZ  1 
ATOM   6603 N  N   . ASP B 1 417 ? 146.811 115.938 142.002 1.00 83.64  ? 417 ASP A N   1 
ATOM   6604 C  CA  . ASP B 1 417 ? 146.588 116.493 140.675 1.00 83.64  ? 417 ASP A CA  1 
ATOM   6605 C  C   . ASP B 1 417 ? 146.302 117.983 140.794 1.00 83.64  ? 417 ASP A C   1 
ATOM   6606 O  O   . ASP B 1 417 ? 145.817 118.457 141.824 1.00 83.64  ? 417 ASP A O   1 
ATOM   6607 C  CB  . ASP B 1 417 ? 145.428 115.789 139.956 1.00 83.64  ? 417 ASP A CB  1 
ATOM   6608 C  CG  . ASP B 1 417 ? 145.524 115.901 138.447 1.00 83.64  ? 417 ASP A CG  1 
ATOM   6609 O  OD1 . ASP B 1 417 ? 145.854 116.997 137.948 1.00 83.64  ? 417 ASP A OD1 1 
ATOM   6610 O  OD2 . ASP B 1 417 ? 145.267 114.892 137.757 1.00 83.64  ? 417 ASP A OD2 1 
ATOM   6611 N  N   . TYR B 1 418 ? 146.608 118.717 139.731 1.00 69.70  ? 418 TYR A N   1 
ATOM   6612 C  CA  . TYR B 1 418 ? 146.437 120.160 139.735 1.00 69.70  ? 418 TYR A CA  1 
ATOM   6613 C  C   . TYR B 1 418 ? 145.078 120.550 139.158 1.00 69.70  ? 418 TYR A C   1 
ATOM   6614 O  O   . TYR B 1 418 ? 144.310 119.716 138.675 1.00 69.70  ? 418 TYR A O   1 
ATOM   6615 C  CB  . TYR B 1 418 ? 147.566 120.834 138.954 1.00 69.70  ? 418 TYR A CB  1 
ATOM   6616 C  CG  . TYR B 1 418 ? 147.476 120.659 137.456 1.00 69.70  ? 418 TYR A CG  1 
ATOM   6617 C  CD1 . TYR B 1 418 ? 148.035 119.556 136.832 1.00 69.70  ? 418 TYR A CD1 1 
ATOM   6618 C  CD2 . TYR B 1 418 ? 146.837 121.602 136.666 1.00 69.70  ? 418 TYR A CD2 1 
ATOM   6619 C  CE1 . TYR B 1 418 ? 147.957 119.397 135.465 1.00 69.70  ? 418 TYR A CE1 1 
ATOM   6620 C  CE2 . TYR B 1 418 ? 146.753 121.451 135.300 1.00 69.70  ? 418 TYR A CE2 1 
ATOM   6621 C  CZ  . TYR B 1 418 ? 147.314 120.348 134.704 1.00 69.70  ? 418 TYR A CZ  1 
ATOM   6622 O  OH  . TYR B 1 418 ? 147.229 120.198 133.340 1.00 69.70  ? 418 TYR A OH  1 
ATOM   6623 N  N   . SER B 1 419 ? 144.787 121.854 139.217 1.00 62.17  ? 419 SER A N   1 
ATOM   6624 C  CA  . SER B 1 419 ? 143.568 122.430 138.677 1.00 62.17  ? 419 SER A CA  1 
ATOM   6625 C  C   . SER B 1 419 ? 143.869 123.208 137.401 1.00 62.17  ? 419 SER A C   1 
ATOM   6626 O  O   . SER B 1 419 ? 144.867 123.933 137.338 1.00 62.17  ? 419 SER A O   1 
ATOM   6627 C  CB  . SER B 1 419 ? 142.899 123.362 139.692 1.00 62.17  ? 419 SER A CB  1 
ATOM   6628 O  OG  . SER B 1 419 ? 142.561 122.661 140.876 1.00 62.17  ? 419 SER A OG  1 
ATOM   6629 N  N   . PRO B 1 420 ? 143.022 123.090 136.377 1.00 53.71  ? 420 PRO A N   1 
ATOM   6630 C  CA  . PRO B 1 420 ? 143.343 123.674 135.070 1.00 53.71  ? 420 PRO A CA  1 
ATOM   6631 C  C   . PRO B 1 420 ? 143.195 125.184 134.995 1.00 53.71  ? 420 PRO A C   1 
ATOM   6632 O  O   . PRO B 1 420 ? 143.369 125.738 133.906 1.00 53.71  ? 420 PRO A O   1 
ATOM   6633 C  CB  . PRO B 1 420 ? 142.335 122.987 134.129 1.00 53.71  ? 420 PRO A CB  1 
ATOM   6634 C  CG  . PRO B 1 420 ? 141.697 121.886 134.936 1.00 53.71  ? 420 PRO A CG  1 
ATOM   6635 C  CD  . PRO B 1 420 ? 141.756 122.346 136.348 1.00 53.71  ? 420 PRO A CD  1 
ATOM   6636 N  N   . LEU B 1 421 ? 142.856 125.844 136.107 1.00 49.70  ? 421 LEU A N   1 
ATOM   6637 C  CA  . LEU B 1 421 ? 142.614 127.285 136.208 1.00 49.70  ? 421 LEU A CA  1 
ATOM   6638 C  C   . LEU B 1 421 ? 141.275 127.660 135.579 1.00 49.70  ? 421 LEU A C   1 
ATOM   6639 O  O   . LEU B 1 421 ? 140.761 128.756 135.815 1.00 49.70  ? 421 LEU A O   1 
ATOM   6640 C  CB  . LEU B 1 421 ? 143.764 128.076 135.567 1.00 49.70  ? 421 LEU A CB  1 
ATOM   6641 C  CG  . LEU B 1 421 ? 143.757 129.604 135.491 1.00 49.70  ? 421 LEU A CG  1 
ATOM   6642 C  CD1 . LEU B 1 421 ? 143.863 130.219 136.867 1.00 49.70  ? 421 LEU A CD1 1 
ATOM   6643 C  CD2 . LEU B 1 421 ? 144.891 130.091 134.612 1.00 49.70  ? 421 LEU A CD2 1 
ATOM   6644 N  N   . ILE B 1 422 ? 140.677 126.721 134.844 1.00 48.32  ? 422 ILE A N   1 
ATOM   6645 C  CA  . ILE B 1 422 ? 139.328 126.801 134.285 1.00 48.32  ? 422 ILE A CA  1 
ATOM   6646 C  C   . ILE B 1 422 ? 138.831 125.376 134.098 1.00 48.32  ? 422 ILE A C   1 
ATOM   6647 O  O   . ILE B 1 422 ? 139.535 124.533 133.532 1.00 48.32  ? 422 ILE A O   1 
ATOM   6648 C  CB  . ILE B 1 422 ? 139.269 127.561 132.942 1.00 48.32  ? 422 ILE A CB  1 
ATOM   6649 C  CG1 . ILE B 1 422 ? 139.568 129.050 133.097 1.00 48.32  ? 422 ILE A CG1 1 
ATOM   6650 C  CG2 . ILE B 1 422 ? 137.905 127.396 132.298 1.00 48.32  ? 422 ILE A CG2 1 
ATOM   6651 C  CD1 . ILE B 1 422 ? 138.522 129.782 133.901 1.00 48.32  ? 422 ILE A CD1 1 
ATOM   6652 N  N   . THR B 1 423 ? 137.623 125.092 134.563 1.00 51.07  ? 423 THR A N   1 
ATOM   6653 C  CA  . THR B 1 423 ? 136.988 123.809 134.313 1.00 51.07  ? 423 THR A CA  1 
ATOM   6654 C  C   . THR B 1 423 ? 135.944 123.966 133.216 1.00 51.07  ? 423 THR A C   1 
ATOM   6655 O  O   . THR B 1 423 ? 135.312 125.016 133.086 1.00 51.07  ? 423 THR A O   1 
ATOM   6656 C  CB  . THR B 1 423 ? 136.338 123.258 135.583 1.00 51.07  ? 423 THR A CB  1 
ATOM   6657 O  OG1 . THR B 1 423 ? 135.214 124.071 135.937 1.00 51.07  ? 423 THR A OG1 1 
ATOM   6658 C  CG2 . THR B 1 423 ? 137.334 123.260 136.729 1.00 51.07  ? 423 THR A CG2 1 
ATOM   6659 N  N   . TRP B 1 424 ? 135.777 122.911 132.414 1.00 51.15  ? 424 TRP A N   1 
ATOM   6660 C  CA  . TRP B 1 424 ? 134.833 122.991 131.305 1.00 51.15  ? 424 TRP A CA  1 
ATOM   6661 C  C   . TRP B 1 424 ? 133.407 123.201 131.792 1.00 51.15  ? 424 TRP A C   1 
ATOM   6662 O  O   . TRP B 1 424 ? 132.595 123.804 131.084 1.00 51.15  ? 424 TRP A O   1 
ATOM   6663 C  CB  . TRP B 1 424 ? 134.908 121.737 130.439 1.00 51.15  ? 424 TRP A CB  1 
ATOM   6664 C  CG  . TRP B 1 424 ? 133.907 121.765 129.334 1.00 51.15  ? 424 TRP A CG  1 
ATOM   6665 C  CD1 . TRP B 1 424 ? 132.725 121.091 129.284 1.00 51.15  ? 424 TRP A CD1 1 
ATOM   6666 C  CD2 . TRP B 1 424 ? 133.982 122.534 128.130 1.00 51.15  ? 424 TRP A CD2 1 
ATOM   6667 N  NE1 . TRP B 1 424 ? 132.064 121.381 128.116 1.00 51.15  ? 424 TRP A NE1 1 
ATOM   6668 C  CE2 . TRP B 1 424 ? 132.816 122.265 127.390 1.00 51.15  ? 424 TRP A CE2 1 
ATOM   6669 C  CE3 . TRP B 1 424 ? 134.927 123.417 127.601 1.00 51.15  ? 424 TRP A CE3 1 
ATOM   6670 C  CZ2 . TRP B 1 424 ? 132.568 122.848 126.151 1.00 51.15  ? 424 TRP A CZ2 1 
ATOM   6671 C  CZ3 . TRP B 1 424 ? 134.680 123.992 126.372 1.00 51.15  ? 424 TRP A CZ3 1 
ATOM   6672 C  CH2 . TRP B 1 424 ? 133.510 123.708 125.661 1.00 51.15  ? 424 TRP A CH2 1 
ATOM   6673 N  N   . LYS B 1 425 ? 133.078 122.713 132.988 1.00 51.78  ? 425 LYS A N   1 
ATOM   6674 C  CA  . LYS B 1 425 ? 131.750 122.972 133.533 1.00 51.78  ? 425 LYS A CA  1 
ATOM   6675 C  C   . LYS B 1 425 ? 131.555 124.449 133.852 1.00 51.78  ? 425 LYS A C   1 
ATOM   6676 O  O   . LYS B 1 425 ? 130.423 124.942 133.821 1.00 51.78  ? 425 LYS A O   1 
ATOM   6677 C  CB  . LYS B 1 425 ? 131.512 122.097 134.767 1.00 51.78  ? 425 LYS A CB  1 
ATOM   6678 C  CG  . LYS B 1 425 ? 132.463 122.333 135.936 1.00 51.78  ? 425 LYS A CG  1 
ATOM   6679 C  CD  . LYS B 1 425 ? 131.914 123.334 136.940 1.00 51.78  ? 425 LYS A CD  1 
ATOM   6680 C  CE  . LYS B 1 425 ? 132.826 123.454 138.149 1.00 51.78  ? 425 LYS A CE  1 
ATOM   6681 N  NZ  . LYS B 1 425 ? 132.312 124.442 139.137 1.00 51.78  ? 425 LYS A NZ  1 
ATOM   6682 N  N   . GLU B 1 426 ? 132.637 125.168 134.157 1.00 54.02  ? 426 GLU A N   1 
ATOM   6683 C  CA  . GLU B 1 426 ? 132.537 126.607 134.373 1.00 54.02  ? 426 GLU A CA  1 
ATOM   6684 C  C   . GLU B 1 426 ? 132.421 127.365 133.057 1.00 54.02  ? 426 GLU A C   1 
ATOM   6685 O  O   . GLU B 1 426 ? 131.721 128.380 132.983 1.00 54.02  ? 426 GLU A O   1 
ATOM   6686 C  CB  . GLU B 1 426 ? 133.737 127.105 135.177 1.00 54.02  ? 426 GLU A CB  1 
ATOM   6687 C  CG  . GLU B 1 426 ? 133.670 126.744 136.649 1.00 54.02  ? 426 GLU A CG  1 
ATOM   6688 C  CD  . GLU B 1 426 ? 134.976 126.988 137.370 1.00 54.02  ? 426 GLU A CD  1 
ATOM   6689 O  OE1 . GLU B 1 426 ? 135.316 128.165 137.598 1.00 54.02  ? 426 GLU A OE1 1 
ATOM   6690 O  OE2 . GLU B 1 426 ? 135.662 126.002 137.709 1.00 54.02  ? 426 GLU A OE2 1 
ATOM   6691 N  N   . PHE B 1 427 ? 133.101 126.893 132.010 1.00 48.70  ? 427 PHE A N   1 
ATOM   6692 C  CA  . PHE B 1 427 ? 132.953 127.507 130.697 1.00 48.70  ? 427 PHE A CA  1 
ATOM   6693 C  C   . PHE B 1 427 ? 131.608 127.183 130.062 1.00 48.70  ? 427 PHE A C   1 
ATOM   6694 O  O   . PHE B 1 427 ? 131.165 127.913 129.170 1.00 48.70  ? 427 PHE A O   1 
ATOM   6695 C  CB  . PHE B 1 427 ? 134.091 127.064 129.778 1.00 48.70  ? 427 PHE A CB  1 
ATOM   6696 C  CG  . PHE B 1 427 ? 134.053 127.694 128.418 1.00 48.70  ? 427 PHE A CG  1 
ATOM   6697 C  CD1 . PHE B 1 427 ? 134.572 128.957 128.212 1.00 48.70  ? 427 PHE A CD1 1 
ATOM   6698 C  CD2 . PHE B 1 427 ? 133.503 127.020 127.344 1.00 48.70  ? 427 PHE A CD2 1 
ATOM   6699 C  CE1 . PHE B 1 427 ? 134.537 129.535 126.961 1.00 48.70  ? 427 PHE A CE1 1 
ATOM   6700 C  CE2 . PHE B 1 427 ? 133.467 127.595 126.093 1.00 48.70  ? 427 PHE A CE2 1 
ATOM   6701 C  CZ  . PHE B 1 427 ? 133.984 128.853 125.902 1.00 48.70  ? 427 PHE A CZ  1 
ATOM   6702 N  N   . GLN B 1 428 ? 130.953 126.105 130.499 1.00 56.79  ? 428 GLN A N   1 
ATOM   6703 C  CA  . GLN B 1 428 ? 129.604 125.817 130.028 1.00 56.79  ? 428 GLN A CA  1 
ATOM   6704 C  C   . GLN B 1 428 ? 128.652 126.944 130.402 1.00 56.79  ? 428 GLN A C   1 
ATOM   6705 O  O   . GLN B 1 428 ? 127.792 127.334 129.603 1.00 56.79  ? 428 GLN A O   1 
ATOM   6706 C  CB  . GLN B 1 428 ? 129.119 124.489 130.606 1.00 56.79  ? 428 GLN A CB  1 
ATOM   6707 C  CG  . GLN B 1 428 ? 127.869 123.938 129.947 1.00 56.79  ? 428 GLN A CG  1 
ATOM   6708 C  CD  . GLN B 1 428 ? 128.175 122.878 128.909 1.00 56.79  ? 428 GLN A CD  1 
ATOM   6709 O  OE1 . GLN B 1 428 ? 129.316 122.438 128.773 1.00 56.79  ? 428 GLN A OE1 1 
ATOM   6710 N  NE2 . GLN B 1 428 ? 127.153 122.458 128.173 1.00 56.79  ? 428 GLN A NE2 1 
ATOM   6711 N  N   . SER B 1 429 ? 128.785 127.472 131.615 1.00 56.50  ? 429 SER A N   1 
ATOM   6712 C  CA  . SER B 1 429 ? 128.105 128.697 131.995 1.00 56.50  ? 429 SER A CA  1 
ATOM   6713 C  C   . SER B 1 429 ? 128.916 129.895 131.510 1.00 56.50  ? 429 SER A C   1 
ATOM   6714 O  O   . SER B 1 429 ? 129.980 129.752 130.903 1.00 56.50  ? 429 SER A O   1 
ATOM   6715 C  CB  . SER B 1 429 ? 127.900 128.749 133.506 1.00 56.50  ? 429 SER A CB  1 
ATOM   6716 O  OG  . SER B 1 429 ? 129.140 128.694 134.187 1.00 56.50  ? 429 SER A OG  1 
ATOM   6717 N  N   . PHE B 1 430 ? 128.405 131.094 131.773 1.00 58.44  ? 430 PHE A N   1 
ATOM   6718 C  CA  . PHE B 1 430 ? 129.040 132.353 131.391 1.00 58.44  ? 430 PHE A CA  1 
ATOM   6719 C  C   . PHE B 1 430 ? 129.232 132.478 129.885 1.00 58.44  ? 430 PHE A C   1 
ATOM   6720 O  O   . PHE B 1 430 ? 130.017 133.319 129.435 1.00 58.44  ? 430 PHE A O   1 
ATOM   6721 C  CB  . PHE B 1 430 ? 130.396 132.552 132.092 1.00 58.44  ? 430 PHE A CB  1 
ATOM   6722 C  CG  . PHE B 1 430 ? 130.336 132.499 133.598 1.00 58.44  ? 430 PHE A CG  1 
ATOM   6723 C  CD1 . PHE B 1 430 ? 129.126 132.491 134.275 1.00 58.44  ? 430 PHE A CD1 1 
ATOM   6724 C  CD2 . PHE B 1 430 ? 131.505 132.443 134.336 1.00 58.44  ? 430 PHE A CD2 1 
ATOM   6725 C  CE1 . PHE B 1 430 ? 129.087 132.437 135.656 1.00 58.44  ? 430 PHE A CE1 1 
ATOM   6726 C  CE2 . PHE B 1 430 ? 131.472 132.387 135.713 1.00 58.44  ? 430 PHE A CE2 1 
ATOM   6727 C  CZ  . PHE B 1 430 ? 130.262 132.386 136.375 1.00 58.44  ? 430 PHE A CZ  1 
ATOM   6728 N  N   . MET B 1 431 ? 128.539 131.662 129.091 1.00 57.25  ? 431 MET A N   1 
ATOM   6729 C  CA  . MET B 1 431 ? 128.760 131.610 127.659 1.00 57.25  ? 431 MET A CA  1 
ATOM   6730 C  C   . MET B 1 431 ? 127.467 131.878 126.897 1.00 57.25  ? 431 MET A C   1 
ATOM   6731 O  O   . MET B 1 431 ? 126.405 131.381 127.286 1.00 57.25  ? 431 MET A O   1 
ATOM   6732 C  CB  . MET B 1 431 ? 129.327 130.242 127.253 1.00 57.25  ? 431 MET A CB  1 
ATOM   6733 C  CG  . MET B 1 431 ? 129.519 130.067 125.767 1.00 57.25  ? 431 MET A CG  1 
ATOM   6734 S  SD  . MET B 1 431 ? 131.085 130.698 125.151 1.00 57.25  ? 431 MET A SD  1 
ATOM   6735 C  CE  . MET B 1 431 ? 130.873 130.479 123.389 1.00 57.25  ? 431 MET A CE  1 
ATOM   6736 N  N   . PRO B 1 432 ? 127.521 132.659 125.813 1.00 58.23  ? 432 PRO A N   1 
ATOM   6737 C  CA  . PRO B 1 432 ? 126.311 133.000 125.042 1.00 58.23  ? 432 PRO A CA  1 
ATOM   6738 C  C   . PRO B 1 432 ? 125.880 131.899 124.074 1.00 58.23  ? 432 PRO A C   1 
ATOM   6739 O  O   . PRO B 1 432 ? 125.887 132.064 122.852 1.00 58.23  ? 432 PRO A O   1 
ATOM   6740 C  CB  . PRO B 1 432 ? 126.741 134.282 124.320 1.00 58.23  ? 432 PRO A CB  1 
ATOM   6741 C  CG  . PRO B 1 432 ? 128.187 134.137 124.135 1.00 58.23  ? 432 PRO A CG  1 
ATOM   6742 C  CD  . PRO B 1 432 ? 128.703 133.392 125.328 1.00 58.23  ? 432 PRO A CD  1 
ATOM   6743 N  N   . TRP B 1 433 ? 125.496 130.755 124.631 1.00 62.55  ? 433 TRP A N   1 
ATOM   6744 C  CA  . TRP B 1 433 ? 124.848 129.673 123.895 1.00 62.55  ? 433 TRP A CA  1 
ATOM   6745 C  C   . TRP B 1 433 ? 123.338 129.831 123.767 1.00 62.55  ? 433 TRP A C   1 
ATOM   6746 O  O   . TRP B 1 433 ? 122.697 128.964 123.165 1.00 62.55  ? 433 TRP A O   1 
ATOM   6747 C  CB  . TRP B 1 433 ? 125.221 128.330 124.535 1.00 62.55  ? 433 TRP A CB  1 
ATOM   6748 C  CG  . TRP B 1 433 ? 126.664 127.971 124.311 1.00 62.55  ? 433 TRP A CG  1 
ATOM   6749 C  CD1 . TRP B 1 433 ? 127.538 128.619 123.493 1.00 62.55  ? 433 TRP A CD1 1 
ATOM   6750 C  CD2 . TRP B 1 433 ? 127.425 126.949 124.973 1.00 62.55  ? 433 TRP A CD2 1 
ATOM   6751 N  NE1 . TRP B 1 433 ? 128.772 128.022 123.544 1.00 62.55  ? 433 TRP A NE1 1 
ATOM   6752 C  CE2 . TRP B 1 433 ? 128.734 127.005 124.460 1.00 62.55  ? 433 TRP A CE2 1 
ATOM   6753 C  CE3 . TRP B 1 433 ? 127.125 125.985 125.935 1.00 62.55  ? 433 TRP A CE3 1 
ATOM   6754 C  CZ2 . TRP B 1 433 ? 129.736 126.135 124.875 1.00 62.55  ? 433 TRP A CZ2 1 
ATOM   6755 C  CZ3 . TRP B 1 433 ? 128.118 125.119 126.342 1.00 62.55  ? 433 TRP A CZ3 1 
ATOM   6756 C  CH2 . TRP B 1 433 ? 129.409 125.200 125.815 1.00 62.55  ? 433 TRP A CH2 1 
ATOM   6757 N  N   . ASP B 1 434 ? 122.751 130.903 124.297 1.00 59.62  ? 434 ASP A N   1 
ATOM   6758 C  CA  . ASP B 1 434 ? 121.350 131.189 124.009 1.00 59.62  ? 434 ASP A CA  1 
ATOM   6759 C  C   . ASP B 1 434 ? 121.168 132.238 122.915 1.00 59.62  ? 434 ASP A C   1 
ATOM   6760 O  O   . ASP B 1 434 ? 120.145 132.220 122.219 1.00 59.62  ? 434 ASP A O   1 
ATOM   6761 C  CB  . ASP B 1 434 ? 120.617 131.606 125.290 1.00 59.62  ? 434 ASP A CB  1 
ATOM   6762 C  CG  . ASP B 1 434 ? 121.402 132.593 126.124 1.00 59.62  ? 434 ASP A CG  1 
ATOM   6763 O  OD1 . ASP B 1 434 ? 122.029 133.496 125.548 1.00 59.62  ? 434 ASP A OD1 1 
ATOM   6764 O  OD2 . ASP B 1 434 ? 121.390 132.462 127.367 1.00 59.62  ? 434 ASP A OD2 1 
ATOM   6765 N  N   . ILE B 1 435 ? 122.137 133.141 122.728 1.00 60.64  ? 435 ILE A N   1 
ATOM   6766 C  CA  . ILE B 1 435 ? 122.104 134.027 121.564 1.00 60.64  ? 435 ILE A CA  1 
ATOM   6767 C  C   . ILE B 1 435 ? 122.200 133.234 120.267 1.00 60.64  ? 435 ILE A C   1 
ATOM   6768 O  O   . ILE B 1 435 ? 121.645 133.644 119.240 1.00 60.64  ? 435 ILE A O   1 
ATOM   6769 C  CB  . ILE B 1 435 ? 123.199 135.116 121.650 1.00 60.64  ? 435 ILE A CB  1 
ATOM   6770 C  CG1 . ILE B 1 435 ? 122.976 136.052 122.846 1.00 60.64  ? 435 ILE A CG1 1 
ATOM   6771 C  CG2 . ILE B 1 435 ? 123.300 135.909 120.362 1.00 60.64  ? 435 ILE A CG2 1 
ATOM   6772 C  CD1 . ILE B 1 435 ? 123.603 135.633 124.132 1.00 60.64  ? 435 ILE A CD1 1 
ATOM   6773 N  N   . ALA B 1 436 ? 122.889 132.091 120.281 1.00 64.30  ? 436 ALA A N   1 
ATOM   6774 C  CA  . ALA B 1 436 ? 122.940 131.256 119.084 1.00 64.30  ? 436 ALA A CA  1 
ATOM   6775 C  C   . ALA B 1 436 ? 121.543 130.803 118.674 1.00 64.30  ? 436 ALA A C   1 
ATOM   6776 O  O   . ALA B 1 436 ? 121.138 130.960 117.515 1.00 64.30  ? 436 ALA A O   1 
ATOM   6777 C  CB  . ALA B 1 436 ? 123.852 130.053 119.324 1.00 64.30  ? 436 ALA A CB  1 
ATOM   6778 N  N   . ILE B 1 437 ? 120.779 130.262 119.625 1.00 62.78  ? 437 ILE A N   1 
ATOM   6779 C  CA  . ILE B 1 437 ? 119.414 129.834 119.335 1.00 62.78  ? 437 ILE A CA  1 
ATOM   6780 C  C   . ILE B 1 437 ? 118.546 131.032 118.976 1.00 62.78  ? 437 ILE A C   1 
ATOM   6781 O  O   . ILE B 1 437 ? 117.648 130.937 118.131 1.00 62.78  ? 437 ILE A O   1 
ATOM   6782 C  CB  . ILE B 1 437 ? 118.833 129.054 120.528 1.00 62.78  ? 437 ILE A CB  1 
ATOM   6783 C  CG1 . ILE B 1 437 ? 119.852 128.038 121.047 1.00 62.78  ? 437 ILE A CG1 1 
ATOM   6784 C  CG2 . ILE B 1 437 ? 117.538 128.366 120.137 1.00 62.78  ? 437 ILE A CG2 1 
ATOM   6785 C  CD1 . ILE B 1 437 ? 119.333 127.176 122.175 1.00 62.78  ? 437 ILE A CD1 1 
ATOM   6786 N  N   . LEU B 1 438 ? 118.790 132.175 119.619 1.00 61.95  ? 438 LEU A N   1 
ATOM   6787 C  CA  . LEU B 1 438 ? 117.999 133.369 119.335 1.00 61.95  ? 438 LEU A CA  1 
ATOM   6788 C  C   . LEU B 1 438 ? 118.177 133.817 117.887 1.00 61.95  ? 438 LEU A C   1 
ATOM   6789 O  O   . LEU B 1 438 ? 117.197 134.059 117.171 1.00 61.95  ? 438 LEU A O   1 
ATOM   6790 C  CB  . LEU B 1 438 ? 118.387 134.482 120.307 1.00 61.95  ? 438 LEU A CB  1 
ATOM   6791 C  CG  . LEU B 1 438 ? 117.438 135.668 120.455 1.00 61.95  ? 438 LEU A CG  1 
ATOM   6792 C  CD1 . LEU B 1 438 ? 117.478 136.183 121.879 1.00 61.95  ? 438 LEU A CD1 1 
ATOM   6793 C  CD2 . LEU B 1 438 ? 117.815 136.767 119.490 1.00 61.95  ? 438 LEU A CD2 1 
ATOM   6794 N  N   . VAL B 1 439 ? 119.427 133.931 117.437 1.00 68.13  ? 439 VAL A N   1 
ATOM   6795 C  CA  . VAL B 1 439 ? 119.675 134.354 116.064 1.00 68.13  ? 439 VAL A CA  1 
ATOM   6796 C  C   . VAL B 1 439 ? 119.236 133.273 115.085 1.00 68.13  ? 439 VAL A C   1 
ATOM   6797 O  O   . VAL B 1 439 ? 118.836 133.577 113.955 1.00 68.13  ? 439 VAL A O   1 
ATOM   6798 C  CB  . VAL B 1 439 ? 121.153 134.748 115.871 1.00 68.13  ? 439 VAL A CB  1 
ATOM   6799 C  CG1 . VAL B 1 439 ? 122.066 133.542 115.997 1.00 68.13  ? 439 VAL A CG1 1 
ATOM   6800 C  CG2 . VAL B 1 439 ? 121.349 135.446 114.536 1.00 68.13  ? 439 VAL A CG2 1 
ATOM   6801 N  N   . GLY B 1 440 ? 119.282 132.002 115.491 1.00 74.57  ? 440 GLY A N   1 
ATOM   6802 C  CA  . GLY B 1 440 ? 118.735 130.956 114.642 1.00 74.57  ? 440 GLY A CA  1 
ATOM   6803 C  C   . GLY B 1 440 ? 117.239 131.096 114.437 1.00 74.57  ? 440 GLY A C   1 
ATOM   6804 O  O   . GLY B 1 440 ? 116.736 130.942 113.321 1.00 74.57  ? 440 GLY A O   1 
ATOM   6805 N  N   . GLY B 1 441 ? 116.507 131.387 115.512 1.00 71.87  ? 441 GLY A N   1 
ATOM   6806 C  CA  . GLY B 1 441 ? 115.084 131.645 115.374 1.00 71.87  ? 441 GLY A CA  1 
ATOM   6807 C  C   . GLY B 1 441 ? 114.803 132.880 114.542 1.00 71.87  ? 441 GLY A C   1 
ATOM   6808 O  O   . GLY B 1 441 ? 113.841 132.917 113.771 1.00 71.87  ? 441 GLY A O   1 
ATOM   6809 N  N   . GLY B 1 442 ? 115.638 133.908 114.689 1.00 72.24  ? 442 GLY A N   1 
ATOM   6810 C  CA  . GLY B 1 442 ? 115.508 135.076 113.834 1.00 72.24  ? 442 GLY A CA  1 
ATOM   6811 C  C   . GLY B 1 442 ? 115.684 134.739 112.365 1.00 72.24  ? 442 GLY A C   1 
ATOM   6812 O  O   . GLY B 1 442 ? 114.922 135.205 111.515 1.00 72.24  ? 442 GLY A O   1 
ATOM   6813 N  N   . PHE B 1 443 ? 116.690 133.919 112.050 1.00 77.16  ? 443 PHE A N   1 
ATOM   6814 C  CA  . PHE B 1 443 ? 116.888 133.471 110.675 1.00 77.16  ? 443 PHE A CA  1 
ATOM   6815 C  C   . PHE B 1 443 ? 115.697 132.667 110.178 1.00 77.16  ? 443 PHE A C   1 
ATOM   6816 O  O   . PHE B 1 443 ? 115.268 132.827 109.030 1.00 77.16  ? 443 PHE A O   1 
ATOM   6817 C  CB  . PHE B 1 443 ? 118.160 132.632 110.566 1.00 77.16  ? 443 PHE A CB  1 
ATOM   6818 C  CG  . PHE B 1 443 ? 119.424 133.410 110.769 1.00 77.16  ? 443 PHE A CG  1 
ATOM   6819 C  CD1 . PHE B 1 443 ? 119.420 134.792 110.726 1.00 77.16  ? 443 PHE A CD1 1 
ATOM   6820 C  CD2 . PHE B 1 443 ? 120.619 132.754 111.010 1.00 77.16  ? 443 PHE A CD2 1 
ATOM   6821 C  CE1 . PHE B 1 443 ? 120.585 135.503 110.913 1.00 77.16  ? 443 PHE A CE1 1 
ATOM   6822 C  CE2 . PHE B 1 443 ? 121.787 133.461 111.200 1.00 77.16  ? 443 PHE A CE2 1 
ATOM   6823 C  CZ  . PHE B 1 443 ? 121.770 134.837 111.150 1.00 77.16  ? 443 PHE A CZ  1 
ATOM   6824 N  N   . ALA B 1 444 ? 115.164 131.780 111.019 1.00 78.39  ? 444 ALA A N   1 
ATOM   6825 C  CA  . ALA B 1 444 ? 114.020 130.971 110.611 1.00 78.39  ? 444 ALA A CA  1 
ATOM   6826 C  C   . ALA B 1 444 ? 112.814 131.849 110.304 1.00 78.39  ? 444 ALA A C   1 
ATOM   6827 O  O   . ALA B 1 444 ? 112.130 131.656 109.293 1.00 78.39  ? 444 ALA A O   1 
ATOM   6828 C  CB  . ALA B 1 444 ? 113.683 129.950 111.698 1.00 78.39  ? 444 ALA A CB  1 
ATOM   6829 N  N   . LEU B 1 445 ? 112.547 132.834 111.165 1.00 77.57  ? 445 LEU A N   1 
ATOM   6830 C  CA  . LEU B 1 445 ? 111.414 133.725 110.939 1.00 77.57  ? 445 LEU A CA  1 
ATOM   6831 C  C   . LEU B 1 445 ? 111.620 134.582 109.697 1.00 77.57  ? 445 LEU A C   1 
ATOM   6832 O  O   . LEU B 1 445 ? 110.680 134.803 108.925 1.00 77.57  ? 445 LEU A O   1 
ATOM   6833 C  CB  . LEU B 1 445 ? 111.181 134.603 112.167 1.00 77.57  ? 445 LEU A CB  1 
ATOM   6834 C  CG  . LEU B 1 445 ? 109.788 135.222 112.272 1.00 77.57  ? 445 LEU A CG  1 
ATOM   6835 C  CD1 . LEU B 1 445 ? 108.720 134.158 112.100 1.00 77.57  ? 445 LEU A CD1 1 
ATOM   6836 C  CD2 . LEU B 1 445 ? 109.624 135.942 113.600 1.00 77.57  ? 445 LEU A CD2 1 
ATOM   6837 N  N   . ALA B 1 446 ? 112.841 135.082 109.489 1.00 83.26  ? 446 ALA A N   1 
ATOM   6838 C  CA  . ALA B 1 446 ? 113.112 135.893 108.307 1.00 83.26  ? 446 ALA A CA  1 
ATOM   6839 C  C   . ALA B 1 446 ? 112.958 135.077 107.031 1.00 83.26  ? 446 ALA A C   1 
ATOM   6840 O  O   . ALA B 1 446 ? 112.360 135.546 106.056 1.00 83.26  ? 446 ALA A O   1 
ATOM   6841 C  CB  . ALA B 1 446 ? 114.513 136.496 108.394 1.00 83.26  ? 446 ALA A CB  1 
ATOM   6842 N  N   . ASP B 1 447 ? 113.485 133.849 107.020 1.00 92.27  ? 447 ASP A N   1 
ATOM   6843 C  CA  . ASP B 1 447 ? 113.352 132.990 105.849 1.00 92.27  ? 447 ASP A CA  1 
ATOM   6844 C  C   . ASP B 1 447 ? 111.902 132.598 105.607 1.00 92.27  ? 447 ASP A C   1 
ATOM   6845 O  O   . ASP B 1 447 ? 111.489 132.442 104.452 1.00 92.27  ? 447 ASP A O   1 
ATOM   6846 C  CB  . ASP B 1 447 ? 114.222 131.744 106.010 1.00 92.27  ? 447 ASP A CB  1 
ATOM   6847 C  CG  . ASP B 1 447 ? 114.669 131.169 104.680 1.00 92.27  ? 447 ASP A CG  1 
ATOM   6848 O  OD1 . ASP B 1 447 ? 114.026 131.468 103.653 1.00 92.27  ? 447 ASP A OD1 1 
ATOM   6849 O  OD2 . ASP B 1 447 ? 115.668 130.418 104.662 1.00 92.27  ? 447 ASP A OD2 1 
ATOM   6850 N  N   . GLY B 1 448 ? 111.120 132.426 106.674 1.00 90.52  ? 448 GLY A N   1 
ATOM   6851 C  CA  . GLY B 1 448 ? 109.692 132.234 106.499 1.00 90.52  ? 448 GLY A CA  1 
ATOM   6852 C  C   . GLY B 1 448 ? 109.043 133.408 105.795 1.00 90.52  ? 448 GLY A C   1 
ATOM   6853 O  O   . GLY B 1 448 ? 108.125 133.235 104.991 1.00 90.52  ? 448 GLY A O   1 
ATOM   6854 N  N   . CYS B 1 449 ? 109.517 134.617 106.081 1.00 95.00  ? 449 CYS A N   1 
ATOM   6855 C  CA  . CYS B 1 449 ? 109.050 135.818 105.392 1.00 95.00  ? 449 CYS A CA  1 
ATOM   6856 C  C   . CYS B 1 449 ? 109.906 136.118 104.166 1.00 95.00  ? 449 CYS A C   1 
ATOM   6857 O  O   . CYS B 1 449 ? 110.365 137.241 103.961 1.00 95.00  ? 449 CYS A O   1 
ATOM   6858 C  CB  . CYS B 1 449 ? 109.045 136.998 106.355 1.00 95.00  ? 449 CYS A CB  1 
ATOM   6859 S  SG  . CYS B 1 449 ? 107.980 136.782 107.792 1.00 95.00  ? 449 CYS A SG  1 
ATOM   6860 N  N   . GLU B 1 450 ? 110.124 135.102 103.334 1.00 97.89  ? 450 GLU A N   1 
ATOM   6861 C  CA  . GLU B 1 450 ? 110.822 135.275 102.066 1.00 97.89  ? 450 GLU A CA  1 
ATOM   6862 C  C   . GLU B 1 450 ? 110.046 134.567 100.967 1.00 97.89  ? 450 GLU A C   1 
ATOM   6863 O  O   . GLU B 1 450 ? 110.181 134.896 99.784  1.00 97.89  ? 450 GLU A O   1 
ATOM   6864 C  CB  . GLU B 1 450 ? 112.254 134.741 102.146 1.00 97.89  ? 450 GLU A CB  1 
ATOM   6865 C  CG  . GLU B 1 450 ? 113.177 135.555 103.038 1.00 97.89  ? 450 GLU A CG  1 
ATOM   6866 C  CD  . GLU B 1 450 ? 114.582 135.668 102.480 1.00 97.89  ? 450 GLU A CD  1 
ATOM   6867 O  OE1 . GLU B 1 450 ? 114.738 136.205 101.363 1.00 97.89  ? 450 GLU A OE1 1 
ATOM   6868 O  OE2 . GLU B 1 450 ? 115.532 135.221 103.159 1.00 97.89  ? 450 GLU A OE2 1 
ATOM   6869 N  N   . GLU B 1 451 ? 109.232 133.594 101.355 1.00 100.37 ? 451 GLU A N   1 
ATOM   6870 C  CA  . GLU B 1 451 ? 108.349 132.882 100.447 1.00 100.37 ? 451 GLU A CA  1 
ATOM   6871 C  C   . GLU B 1 451 ? 106.908 133.282 100.754 1.00 100.37 ? 451 GLU A C   1 
ATOM   6872 O  O   . GLU B 1 451 ? 106.654 134.185 101.556 1.00 100.37 ? 451 GLU A O   1 
ATOM   6873 C  CB  . GLU B 1 451 ? 108.567 131.371 100.545 1.00 100.37 ? 451 GLU A CB  1 
ATOM   6874 C  CG  . GLU B 1 451 ? 107.999 130.724 101.792 1.00 100.37 ? 451 GLU A CG  1 
ATOM   6875 C  CD  . GLU B 1 451 ? 108.146 129.217 101.770 1.00 100.37 ? 451 GLU A CD  1 
ATOM   6876 O  OE1 . GLU B 1 451 ? 109.280 128.732 101.571 1.00 100.37 ? 451 GLU A OE1 1 
ATOM   6877 O  OE2 . GLU B 1 451 ? 107.126 128.517 101.942 1.00 100.37 ? 451 GLU A OE2 1 
ATOM   6878 N  N   . SER B 1 452 ? 105.966 132.607 100.093 1.00 99.96  ? 452 SER A N   1 
ATOM   6879 C  CA  . SER B 1 452 ? 104.556 132.977 100.124 1.00 99.96  ? 452 SER A CA  1 
ATOM   6880 C  C   . SER B 1 452 ? 104.387 134.367 99.524  1.00 99.96  ? 452 SER A C   1 
ATOM   6881 O  O   . SER B 1 452 ? 104.817 134.612 98.392  1.00 99.96  ? 452 SER A O   1 
ATOM   6882 C  CB  . SER B 1 452 ? 103.994 132.913 101.548 1.00 99.96  ? 452 SER A CB  1 
ATOM   6883 O  OG  . SER B 1 452 ? 102.782 133.640 101.652 1.00 99.96  ? 452 SER A OG  1 
ATOM   6884 N  N   . GLY B 1 453 ? 103.764 135.283 100.259 1.00 100.61 ? 453 GLY A N   1 
ATOM   6885 C  CA  . GLY B 1 453 ? 103.585 136.627 99.749  1.00 100.61 ? 453 GLY A CA  1 
ATOM   6886 C  C   . GLY B 1 453 ? 103.665 137.707 100.807 1.00 100.61 ? 453 GLY A C   1 
ATOM   6887 O  O   . GLY B 1 453 ? 103.376 138.875 100.529 1.00 100.61 ? 453 GLY A O   1 
ATOM   6888 N  N   . LEU B 1 454 ? 104.049 137.331 102.028 1.00 96.47  ? 454 LEU A N   1 
ATOM   6889 C  CA  . LEU B 1 454 ? 104.094 138.307 103.112 1.00 96.47  ? 454 LEU A CA  1 
ATOM   6890 C  C   . LEU B 1 454 ? 105.162 139.364 102.861 1.00 96.47  ? 454 LEU A C   1 
ATOM   6891 O  O   . LEU B 1 454 ? 104.954 140.548 103.152 1.00 96.47  ? 454 LEU A O   1 
ATOM   6892 C  CB  . LEU B 1 454 ? 104.327 137.604 104.448 1.00 96.47  ? 454 LEU A CB  1 
ATOM   6893 C  CG  . LEU B 1 454 ? 104.324 138.531 105.663 1.00 96.47  ? 454 LEU A CG  1 
ATOM   6894 C  CD1 . LEU B 1 454 ? 102.967 139.190 105.807 1.00 96.47  ? 454 LEU A CD1 1 
ATOM   6895 C  CD2 . LEU B 1 454 ? 104.664 137.759 106.920 1.00 96.47  ? 454 LEU A CD2 1 
ATOM   6896 N  N   . SER B 1 455 ? 106.313 138.958 102.318 1.00 96.60  ? 455 SER A N   1 
ATOM   6897 C  CA  . SER B 1 455 ? 107.370 139.922 102.030 1.00 96.60  ? 455 SER A CA  1 
ATOM   6898 C  C   . SER B 1 455 ? 106.899 140.977 101.040 1.00 96.60  ? 455 SER A C   1 
ATOM   6899 O  O   . SER B 1 455 ? 107.138 142.172 101.237 1.00 96.60  ? 455 SER A O   1 
ATOM   6900 C  CB  . SER B 1 455 ? 108.607 139.207 101.494 1.00 96.60  ? 455 SER A CB  1 
ATOM   6901 O  OG  . SER B 1 455 ? 109.236 138.452 102.510 1.00 96.60  ? 455 SER A OG  1 
ATOM   6902 N  N   . LYS B 1 456 ? 106.221 140.557 99.971  1.00 100.57 ? 456 LYS A N   1 
ATOM   6903 C  CA  . LYS B 1 456 ? 105.697 141.521 99.009  1.00 100.57 ? 456 LYS A CA  1 
ATOM   6904 C  C   . LYS B 1 456 ? 104.572 142.350 99.616  1.00 100.57 ? 456 LYS A C   1 
ATOM   6905 O  O   . LYS B 1 456 ? 104.438 143.543 99.315  1.00 100.57 ? 456 LYS A O   1 
ATOM   6906 C  CB  . LYS B 1 456 ? 105.218 140.798 97.751  1.00 100.57 ? 456 LYS A CB  1 
ATOM   6907 C  CG  . LYS B 1 456 ? 106.314 140.037 97.024  1.00 100.57 ? 456 LYS A CG  1 
ATOM   6908 C  CD  . LYS B 1 456 ? 105.762 139.262 95.840  1.00 100.57 ? 456 LYS A CD  1 
ATOM   6909 C  CE  . LYS B 1 456 ? 104.862 140.132 94.978  1.00 100.57 ? 456 LYS A CE  1 
ATOM   6910 N  NZ  . LYS B 1 456 ? 105.644 140.945 94.007  1.00 100.57 ? 456 LYS A NZ  1 
ATOM   6911 N  N   . TRP B 1 457 ? 103.753 141.734 100.473 1.00 102.63 ? 457 TRP A N   1 
ATOM   6912 C  CA  . TRP B 1 457 ? 102.677 142.468 101.129 1.00 102.63 ? 457 TRP A CA  1 
ATOM   6913 C  C   . TRP B 1 457 ? 103.224 143.565 102.032 1.00 102.63 ? 457 TRP A C   1 
ATOM   6914 O  O   . TRP B 1 457 ? 102.575 144.601 102.213 1.00 102.63 ? 457 TRP A O   1 
ATOM   6915 C  CB  . TRP B 1 457 ? 101.799 141.500 101.924 1.00 102.63 ? 457 TRP A CB  1 
ATOM   6916 C  CG  . TRP B 1 457 ? 100.420 142.013 102.227 1.00 102.63 ? 457 TRP A CG  1 
ATOM   6917 C  CD1 . TRP B 1 457 ? 100.093 143.200 102.813 1.00 102.63 ? 457 TRP A CD1 1 
ATOM   6918 C  CD2 . TRP B 1 457 ? 99.181  141.346 101.956 1.00 102.63 ? 457 TRP A CD2 1 
ATOM   6919 N  NE1 . TRP B 1 457 ? 98.729  143.315 102.923 1.00 102.63 ? 457 TRP A NE1 1 
ATOM   6920 C  CE2 . TRP B 1 457 ? 98.146  142.189 102.404 1.00 102.63 ? 457 TRP A CE2 1 
ATOM   6921 C  CE3 . TRP B 1 457 ? 98.848  140.117 101.378 1.00 102.63 ? 457 TRP A CE3 1 
ATOM   6922 C  CZ2 . TRP B 1 457 ? 96.801  141.844 102.292 1.00 102.63 ? 457 TRP A CZ2 1 
ATOM   6923 C  CZ3 . TRP B 1 457 ? 97.512  139.777 101.267 1.00 102.63 ? 457 TRP A CZ3 1 
ATOM   6924 C  CH2 . TRP B 1 457 ? 96.505  140.637 101.722 1.00 102.63 ? 457 TRP A CH2 1 
ATOM   6925 N  N   . ILE B 1 458 ? 104.409 143.363 102.606 1.00 100.68 ? 458 ILE A N   1 
ATOM   6926 C  CA  . ILE B 1 458 ? 105.025 144.419 103.403 1.00 100.68 ? 458 ILE A CA  1 
ATOM   6927 C  C   . ILE B 1 458 ? 105.749 145.420 102.510 1.00 100.68 ? 458 ILE A C   1 
ATOM   6928 O  O   . ILE B 1 458 ? 105.713 146.630 102.759 1.00 100.68 ? 458 ILE A O   1 
ATOM   6929 C  CB  . ILE B 1 458 ? 105.968 143.814 104.460 1.00 100.68 ? 458 ILE A CB  1 
ATOM   6930 C  CG1 . ILE B 1 458 ? 105.226 142.793 105.324 1.00 100.68 ? 458 ILE A CG1 1 
ATOM   6931 C  CG2 . ILE B 1 458 ? 106.569 144.905 105.330 1.00 100.68 ? 458 ILE A CG2 1 
ATOM   6932 C  CD1 . ILE B 1 458 ? 103.879 143.273 105.825 1.00 100.68 ? 458 ILE A CD1 1 
ATOM   6933 N  N   . GLY B 1 459 ? 106.405 144.940 101.454 1.00 106.06 ? 459 GLY A N   1 
ATOM   6934 C  CA  . GLY B 1 459 ? 107.192 145.800 100.594 1.00 106.06 ? 459 GLY A CA  1 
ATOM   6935 C  C   . GLY B 1 459 ? 106.407 146.693 99.661  1.00 106.06 ? 459 GLY A C   1 
ATOM   6936 O  O   . GLY B 1 459 ? 106.961 147.682 99.173  1.00 106.06 ? 459 GLY A O   1 
ATOM   6937 N  N   . ASN B 1 460 ? 105.139 146.374 99.384  1.00 107.93 ? 460 ASN A N   1 
ATOM   6938 C  CA  . ASN B 1 460 ? 104.354 147.261 98.531  1.00 107.93 ? 460 ASN A CA  1 
ATOM   6939 C  C   . ASN B 1 460 ? 104.039 148.578 99.233  1.00 107.93 ? 460 ASN A C   1 
ATOM   6940 O  O   . ASN B 1 460 ? 103.756 149.581 98.569  1.00 107.93 ? 460 ASN A O   1 
ATOM   6941 C  CB  . ASN B 1 460 ? 103.075 146.563 98.059  1.00 107.93 ? 460 ASN A CB  1 
ATOM   6942 C  CG  . ASN B 1 460 ? 102.110 146.266 99.187  1.00 107.93 ? 460 ASN A CG  1 
ATOM   6943 O  OD1 . ASN B 1 460 ? 102.392 146.535 100.350 1.00 107.93 ? 460 ASN A OD1 1 
ATOM   6944 N  ND2 . ASN B 1 460 ? 100.955 145.708 98.843  1.00 107.93 ? 460 ASN A ND2 1 
ATOM   6945 N  N   . LYS B 1 461 ? 104.079 148.596 100.570 1.00 108.63 ? 461 LYS A N   1 
ATOM   6946 C  CA  . LYS B 1 461 ? 104.009 149.860 101.295 1.00 108.63 ? 461 LYS A CA  1 
ATOM   6947 C  C   . LYS B 1 461 ? 105.222 150.741 101.036 1.00 108.63 ? 461 LYS A C   1 
ATOM   6948 O  O   . LYS B 1 461 ? 105.140 151.959 101.225 1.00 108.63 ? 461 LYS A O   1 
ATOM   6949 C  CB  . LYS B 1 461 ? 103.873 149.621 102.802 1.00 108.63 ? 461 LYS A CB  1 
ATOM   6950 C  CG  . LYS B 1 461 ? 102.448 149.417 103.304 1.00 108.63 ? 461 LYS A CG  1 
ATOM   6951 C  CD  . LYS B 1 461 ? 101.904 148.045 102.965 1.00 108.63 ? 461 LYS A CD  1 
ATOM   6952 C  CE  . LYS B 1 461 ? 100.519 147.841 103.557 1.00 108.63 ? 461 LYS A CE  1 
ATOM   6953 N  NZ  . LYS B 1 461 ? 99.919  146.544 103.138 1.00 108.63 ? 461 LYS A NZ  1 
ATOM   6954 N  N   . LEU B 1 462 ? 106.348 150.156 100.621 1.00 109.14 ? 462 LEU A N   1 
ATOM   6955 C  CA  . LEU B 1 462 ? 107.527 150.952 100.305 1.00 109.14 ? 462 LEU A CA  1 
ATOM   6956 C  C   . LEU B 1 462 ? 107.370 151.716 98.997  1.00 109.14 ? 462 LEU A C   1 
ATOM   6957 O  O   . LEU B 1 462 ? 108.107 152.679 98.766  1.00 109.14 ? 462 LEU A O   1 
ATOM   6958 C  CB  . LEU B 1 462 ? 108.766 150.053 100.247 1.00 109.14 ? 462 LEU A CB  1 
ATOM   6959 C  CG  . LEU B 1 462 ? 110.143 150.714 100.151 1.00 109.14 ? 462 LEU A CG  1 
ATOM   6960 C  CD1 . LEU B 1 462 ? 110.407 151.585 101.368 1.00 109.14 ? 462 LEU A CD1 1 
ATOM   6961 C  CD2 . LEU B 1 462 ? 111.232 149.665 99.993  1.00 109.14 ? 462 LEU A CD2 1 
ATOM   6962 N  N   . SER B 1 463 ? 106.434 151.311 98.138  1.00 110.67 ? 463 SER A N   1 
ATOM   6963 C  CA  . SER B 1 463 ? 106.240 152.017 96.873  1.00 110.67 ? 463 SER A CA  1 
ATOM   6964 C  C   . SER B 1 463 ? 105.816 153.468 97.069  1.00 110.67 ? 463 SER A C   1 
ATOM   6965 O  O   . SER B 1 463 ? 106.413 154.350 96.428  1.00 110.67 ? 463 SER A O   1 
ATOM   6966 C  CB  . SER B 1 463 ? 105.247 151.245 95.996  1.00 110.67 ? 463 SER A CB  1 
ATOM   6967 O  OG  . SER B 1 463 ? 105.855 150.100 95.424  1.00 110.67 ? 463 SER A OG  1 
ATOM   6968 N  N   . PRO B 1 464 ? 104.818 153.796 97.902  1.00 112.12 ? 464 PRO A N   1 
ATOM   6969 C  CA  . PRO B 1 464 ? 104.574 155.219 98.193  1.00 112.12 ? 464 PRO A CA  1 
ATOM   6970 C  C   . PRO B 1 464 ? 105.758 155.902 98.852  1.00 112.12 ? 464 PRO A C   1 
ATOM   6971 O  O   . PRO B 1 464 ? 105.986 157.096 98.619  1.00 112.12 ? 464 PRO A O   1 
ATOM   6972 C  CB  . PRO B 1 464 ? 103.352 155.186 99.122  1.00 112.12 ? 464 PRO A CB  1 
ATOM   6973 C  CG  . PRO B 1 464 ? 102.692 153.888 98.837  1.00 112.12 ? 464 PRO A CG  1 
ATOM   6974 C  CD  . PRO B 1 464 ? 103.803 152.936 98.536  1.00 112.12 ? 464 PRO A CD  1 
ATOM   6975 N  N   . LEU B 1 465 ? 106.517 155.179 99.667  1.00 108.16 ? 465 LEU A N   1 
ATOM   6976 C  CA  . LEU B 1 465 ? 107.704 155.712 100.315 1.00 108.16 ? 465 LEU A CA  1 
ATOM   6977 C  C   . LEU B 1 465 ? 108.906 155.544 99.386  1.00 108.16 ? 465 LEU A C   1 
ATOM   6978 O  O   . LEU B 1 465 ? 108.763 155.282 98.189  1.00 108.16 ? 465 LEU A O   1 
ATOM   6979 C  CB  . LEU B 1 465 ? 107.923 155.034 101.667 1.00 108.16 ? 465 LEU A CB  1 
ATOM   6980 C  CG  . LEU B 1 465 ? 107.235 155.650 102.889 1.00 108.16 ? 465 LEU A CG  1 
ATOM   6981 C  CD1 . LEU B 1 465 ? 107.714 157.077 103.112 1.00 108.16 ? 465 LEU A CD1 1 
ATOM   6982 C  CD2 . LEU B 1 465 ? 105.718 155.601 102.769 1.00 108.16 ? 465 LEU A CD2 1 
ATOM   6983 N  N   . GLY B 1 466 ? 110.109 155.714 99.928  1.00 101.11 ? 466 GLY A N   1 
ATOM   6984 C  CA  . GLY B 1 466 ? 111.325 155.598 99.160  1.00 101.11 ? 466 GLY A CA  1 
ATOM   6985 C  C   . GLY B 1 466 ? 111.863 156.906 98.626  1.00 101.11 ? 466 GLY A C   1 
ATOM   6986 O  O   . GLY B 1 466 ? 113.046 156.979 98.278  1.00 101.11 ? 466 GLY A O   1 
ATOM   6987 N  N   . SER B 1 467 ? 111.028 157.942 98.552  1.00 98.25  ? 467 SER A N   1 
ATOM   6988 C  CA  . SER B 1 467 ? 111.496 159.276 98.205  1.00 98.25  ? 467 SER A CA  1 
ATOM   6989 C  C   . SER B 1 467 ? 112.167 159.976 99.376  1.00 98.25  ? 467 SER A C   1 
ATOM   6990 O  O   . SER B 1 467 ? 112.809 161.013 99.174  1.00 98.25  ? 467 SER A O   1 
ATOM   6991 C  CB  . SER B 1 467 ? 110.330 160.126 97.695  1.00 98.25  ? 467 SER A CB  1 
ATOM   6992 O  OG  . SER B 1 467 ? 109.208 160.015 98.553  1.00 98.25  ? 467 SER A OG  1 
ATOM   6993 N  N   . LEU B 1 468 ? 112.027 159.440 100.583 1.00 87.24  ? 468 LEU A N   1 
ATOM   6994 C  CA  . LEU B 1 468 ? 112.681 160.021 101.742 1.00 87.24  ? 468 LEU A CA  1 
ATOM   6995 C  C   . LEU B 1 468 ? 114.195 159.870 101.615 1.00 87.24  ? 468 LEU A C   1 
ATOM   6996 O  O   . LEU B 1 468 ? 114.680 158.834 101.149 1.00 87.24  ? 468 LEU A O   1 
ATOM   6997 C  CB  . LEU B 1 468 ? 112.191 159.340 103.018 1.00 87.24  ? 468 LEU A CB  1 
ATOM   6998 C  CG  . LEU B 1 468 ? 110.735 159.601 103.412 1.00 87.24  ? 468 LEU A CG  1 
ATOM   6999 C  CD1 . LEU B 1 468 ? 110.525 159.374 104.901 1.00 87.24  ? 468 LEU A CD1 1 
ATOM   7000 C  CD2 . LEU B 1 468 ? 110.310 161.009 103.019 1.00 87.24  ? 468 LEU A CD2 1 
ATOM   7001 N  N   . PRO B 1 469 ? 114.965 160.879 102.012 1.00 79.43  ? 469 PRO A N   1 
ATOM   7002 C  CA  . PRO B 1 469 ? 116.424 160.767 101.934 1.00 79.43  ? 469 PRO A CA  1 
ATOM   7003 C  C   . PRO B 1 469 ? 116.957 159.755 102.937 1.00 79.43  ? 469 PRO A C   1 
ATOM   7004 O  O   . PRO B 1 469 ? 116.292 159.384 103.906 1.00 79.43  ? 469 PRO A O   1 
ATOM   7005 C  CB  . PRO B 1 469 ? 116.910 162.183 102.256 1.00 79.43  ? 469 PRO A CB  1 
ATOM   7006 C  CG  . PRO B 1 469 ? 115.806 162.784 103.054 1.00 79.43  ? 469 PRO A CG  1 
ATOM   7007 C  CD  . PRO B 1 469 ? 114.533 162.188 102.529 1.00 79.43  ? 469 PRO A CD  1 
ATOM   7008 N  N   . ALA B 1 470 ? 118.187 159.304 102.679 1.00 74.09  ? 470 ALA A N   1 
ATOM   7009 C  CA  . ALA B 1 470 ? 118.780 158.253 103.502 1.00 74.09  ? 470 ALA A CA  1 
ATOM   7010 C  C   . ALA B 1 470 ? 118.937 158.697 104.951 1.00 74.09  ? 470 ALA A C   1 
ATOM   7011 O  O   . ALA B 1 470 ? 118.649 157.927 105.875 1.00 74.09  ? 470 ALA A O   1 
ATOM   7012 C  CB  . ALA B 1 470 ? 120.129 157.832 102.921 1.00 74.09  ? 470 ALA A CB  1 
ATOM   7013 N  N   . TRP B 1 471 ? 119.388 159.935 105.171 1.00 73.92  ? 471 TRP A N   1 
ATOM   7014 C  CA  . TRP B 1 471 ? 119.585 160.415 106.536 1.00 73.92  ? 471 TRP A CA  1 
ATOM   7015 C  C   . TRP B 1 471 ? 118.271 160.443 107.304 1.00 73.92  ? 471 TRP A C   1 
ATOM   7016 O  O   . TRP B 1 471 ? 118.234 160.142 108.503 1.00 73.92  ? 471 TRP A O   1 
ATOM   7017 C  CB  . TRP B 1 471 ? 120.229 161.801 106.521 1.00 73.92  ? 471 TRP A CB  1 
ATOM   7018 C  CG  . TRP B 1 471 ? 119.426 162.838 105.799 1.00 73.92  ? 471 TRP A CG  1 
ATOM   7019 C  CD1 . TRP B 1 471 ? 119.529 163.184 104.484 1.00 73.92  ? 471 TRP A CD1 1 
ATOM   7020 C  CD2 . TRP B 1 471 ? 118.398 163.669 106.352 1.00 73.92  ? 471 TRP A CD2 1 
ATOM   7021 N  NE1 . TRP B 1 471 ? 118.630 164.176 104.184 1.00 73.92  ? 471 TRP A NE1 1 
ATOM   7022 C  CE2 . TRP B 1 471 ? 117.922 164.491 105.313 1.00 73.92  ? 471 TRP A CE2 1 
ATOM   7023 C  CE3 . TRP B 1 471 ? 117.834 163.796 107.624 1.00 73.92  ? 471 TRP A CE3 1 
ATOM   7024 C  CZ2 . TRP B 1 471 ? 116.909 165.426 105.506 1.00 73.92  ? 471 TRP A CZ2 1 
ATOM   7025 C  CZ3 . TRP B 1 471 ? 116.828 164.725 107.813 1.00 73.92  ? 471 TRP A CZ3 1 
ATOM   7026 C  CH2 . TRP B 1 471 ? 116.376 165.527 106.761 1.00 73.92  ? 471 TRP A CH2 1 
ATOM   7027 N  N   . LEU B 1 472 ? 117.179 160.798 106.629 1.00 70.77  ? 472 LEU A N   1 
ATOM   7028 C  CA  . LEU B 1 472 ? 115.880 160.792 107.290 1.00 70.77  ? 472 LEU A CA  1 
ATOM   7029 C  C   . LEU B 1 472 ? 115.486 159.377 107.697 1.00 70.77  ? 472 LEU A C   1 
ATOM   7030 O  O   . LEU B 1 472 ? 114.965 159.161 108.800 1.00 70.77  ? 472 LEU A O   1 
ATOM   7031 C  CB  . LEU B 1 472 ? 114.834 161.415 106.368 1.00 70.77  ? 472 LEU A CB  1 
ATOM   7032 C  CG  . LEU B 1 472 ? 113.410 161.564 106.891 1.00 70.77  ? 472 LEU A CG  1 
ATOM   7033 C  CD1 . LEU B 1 472 ? 113.414 162.412 108.150 1.00 70.77  ? 472 LEU A CD1 1 
ATOM   7034 C  CD2 . LEU B 1 472 ? 112.536 162.197 105.829 1.00 70.77  ? 472 LEU A CD2 1 
ATOM   7035 N  N   . ILE B 1 473 ? 115.739 158.399 106.824 1.00 65.60  ? 473 ILE A N   1 
ATOM   7036 C  CA  . ILE B 1 473 ? 115.469 157.006 107.164 1.00 65.60  ? 473 ILE A CA  1 
ATOM   7037 C  C   . ILE B 1 473 ? 116.291 156.591 108.376 1.00 65.60  ? 473 ILE A C   1 
ATOM   7038 O  O   . ILE B 1 473 ? 115.797 155.891 109.268 1.00 65.60  ? 473 ILE A O   1 
ATOM   7039 C  CB  . ILE B 1 473 ? 115.745 156.096 105.954 1.00 65.60  ? 473 ILE A CB  1 
ATOM   7040 C  CG1 . ILE B 1 473 ? 114.904 156.536 104.755 1.00 65.60  ? 473 ILE A CG1 1 
ATOM   7041 C  CG2 . ILE B 1 473 ? 115.465 154.646 106.304 1.00 65.60  ? 473 ILE A CG2 1 
ATOM   7042 C  CD1 . ILE B 1 473 ? 113.430 156.245 104.903 1.00 65.60  ? 473 ILE A CD1 1 
ATOM   7043 N  N   . ILE B 1 474 ? 117.554 157.023 108.429 1.00 63.30  ? 474 ILE A N   1 
ATOM   7044 C  CA  . ILE B 1 474 ? 118.377 156.786 109.612 1.00 63.30  ? 474 ILE A CA  1 
ATOM   7045 C  C   . ILE B 1 474 ? 117.709 157.369 110.847 1.00 63.30  ? 474 ILE A C   1 
ATOM   7046 O  O   . ILE B 1 474 ? 117.680 156.742 111.912 1.00 63.30  ? 474 ILE A O   1 
ATOM   7047 C  CB  . ILE B 1 474 ? 119.785 157.378 109.419 1.00 63.30  ? 474 ILE A CB  1 
ATOM   7048 C  CG1 . ILE B 1 474 ? 120.429 156.835 108.149 1.00 63.30  ? 474 ILE A CG1 1 
ATOM   7049 C  CG2 . ILE B 1 474 ? 120.656 157.087 110.629 1.00 63.30  ? 474 ILE A CG2 1 
ATOM   7050 C  CD1 . ILE B 1 474 ? 120.933 155.443 108.301 1.00 63.30  ? 474 ILE A CD1 1 
ATOM   7051 N  N   . LEU B 1 475 ? 117.176 158.584 110.724 1.00 62.60  ? 475 LEU A N   1 
ATOM   7052 C  CA  . LEU B 1 475 ? 116.591 159.260 111.877 1.00 62.60  ? 475 LEU A CA  1 
ATOM   7053 C  C   . LEU B 1 475 ? 115.395 158.486 112.421 1.00 62.60  ? 475 LEU A C   1 
ATOM   7054 O  O   . LEU B 1 475 ? 115.333 158.179 113.619 1.00 62.60  ? 475 LEU A O   1 
ATOM   7055 C  CB  . LEU B 1 475 ? 116.189 160.684 111.493 1.00 62.60  ? 475 LEU A CB  1 
ATOM   7056 C  CG  . LEU B 1 475 ? 115.618 161.567 112.600 1.00 62.60  ? 475 LEU A CG  1 
ATOM   7057 C  CD1 . LEU B 1 475 ? 116.659 161.782 113.684 1.00 62.60  ? 475 LEU A CD1 1 
ATOM   7058 C  CD2 . LEU B 1 475 ? 115.150 162.897 112.034 1.00 62.60  ? 475 LEU A CD2 1 
ATOM   7059 N  N   . ILE B 1 476 ? 114.436 158.147 111.552 1.00 61.74  ? 476 ILE A N   1 
ATOM   7060 C  CA  . ILE B 1 476 ? 113.279 157.380 112.025 1.00 61.74  ? 476 ILE A CA  1 
ATOM   7061 C  C   . ILE B 1 476 ? 113.698 156.010 112.547 1.00 61.74  ? 476 ILE A C   1 
ATOM   7062 O  O   . ILE B 1 476 ? 113.178 155.546 113.567 1.00 61.74  ? 476 ILE A O   1 
ATOM   7063 C  CB  . ILE B 1 476 ? 112.163 157.265 110.964 1.00 61.74  ? 476 ILE A CB  1 
ATOM   7064 C  CG1 . ILE B 1 476 ? 111.553 158.626 110.609 1.00 61.74  ? 476 ILE A CG1 1 
ATOM   7065 C  CG2 . ILE B 1 476 ? 111.069 156.317 111.429 1.00 61.74  ? 476 ILE A CG2 1 
ATOM   7066 C  CD1 . ILE B 1 476 ? 112.189 159.370 109.519 1.00 61.74  ? 476 ILE A CD1 1 
ATOM   7067 N  N   . SER B 1 477 ? 114.632 155.336 111.873 1.00 60.73  ? 477 SER A N   1 
ATOM   7068 C  CA  . SER B 1 477 ? 115.041 154.013 112.338 1.00 60.73  ? 477 SER A CA  1 
ATOM   7069 C  C   . SER B 1 477 ? 115.640 154.084 113.738 1.00 60.73  ? 477 SER A C   1 
ATOM   7070 O  O   . SER B 1 477 ? 115.285 153.292 114.620 1.00 60.73  ? 477 SER A O   1 
ATOM   7071 C  CB  . SER B 1 477 ? 116.037 153.397 111.358 1.00 60.73  ? 477 SER A CB  1 
ATOM   7072 O  OG  . SER B 1 477 ? 117.313 153.996 111.491 1.00 60.73  ? 477 SER A OG  1 
ATOM   7073 N  N   . SER B 1 478 ? 116.539 155.045 113.965 1.00 57.54  ? 478 SER A N   1 
ATOM   7074 C  CA  . SER B 1 478 ? 117.178 155.170 115.270 1.00 57.54  ? 478 SER A CA  1 
ATOM   7075 C  C   . SER B 1 478 ? 116.172 155.546 116.348 1.00 57.54  ? 478 SER A C   1 
ATOM   7076 O  O   . SER B 1 478 ? 116.209 154.998 117.456 1.00 57.54  ? 478 SER A O   1 
ATOM   7077 C  CB  . SER B 1 478 ? 118.304 156.199 115.205 1.00 57.54  ? 478 SER A CB  1 
ATOM   7078 O  OG  . SER B 1 478 ? 119.301 155.804 114.280 1.00 57.54  ? 478 SER A OG  1 
ATOM   7079 N  N   . LEU B 1 479 ? 115.265 156.483 116.049 1.00 57.20  ? 479 LEU A N   1 
ATOM   7080 C  CA  . LEU B 1 479 ? 114.261 156.857 117.042 1.00 57.20  ? 479 LEU A CA  1 
ATOM   7081 C  C   . LEU B 1 479 ? 113.336 155.693 117.372 1.00 57.20  ? 479 LEU A C   1 
ATOM   7082 O  O   . LEU B 1 479 ? 113.004 155.476 118.541 1.00 57.20  ? 479 LEU A O   1 
ATOM   7083 C  CB  . LEU B 1 479 ? 113.462 158.074 116.573 1.00 57.20  ? 479 LEU A CB  1 
ATOM   7084 C  CG  . LEU B 1 479 ? 114.040 159.459 116.883 1.00 57.20  ? 479 LEU A CG  1 
ATOM   7085 C  CD1 . LEU B 1 479 ? 114.070 159.666 118.386 1.00 57.20  ? 479 LEU A CD1 1 
ATOM   7086 C  CD2 . LEU B 1 479 ? 115.429 159.656 116.316 1.00 57.20  ? 479 LEU A CD2 1 
ATOM   7087 N  N   . MET B 1 480 ? 112.913 154.927 116.364 1.00 59.02  ? 480 MET A N   1 
ATOM   7088 C  CA  . MET B 1 480 ? 112.052 153.779 116.633 1.00 59.02  ? 480 MET A CA  1 
ATOM   7089 C  C   . MET B 1 480 ? 112.772 152.731 117.470 1.00 59.02  ? 480 MET A C   1 
ATOM   7090 O  O   . MET B 1 480 ? 112.190 152.172 118.408 1.00 59.02  ? 480 MET A O   1 
ATOM   7091 C  CB  . MET B 1 480 ? 111.548 153.169 115.326 1.00 59.02  ? 480 MET A CB  1 
ATOM   7092 C  CG  . MET B 1 480 ? 110.567 154.047 114.569 1.00 59.02  ? 480 MET A CG  1 
ATOM   7093 S  SD  . MET B 1 480 ? 109.662 153.153 113.291 1.00 59.02  ? 480 MET A SD  1 
ATOM   7094 C  CE  . MET B 1 480 ? 110.882 151.947 112.780 1.00 59.02  ? 480 MET A CE  1 
ATOM   7095 N  N   . VAL B 1 481 ? 114.039 152.452 117.154 1.00 52.51  ? 481 VAL A N   1 
ATOM   7096 C  CA  . VAL B 1 481 ? 114.779 151.457 117.923 1.00 52.51  ? 481 VAL A CA  1 
ATOM   7097 C  C   . VAL B 1 481 ? 114.955 151.913 119.366 1.00 52.51  ? 481 VAL A C   1 
ATOM   7098 O  O   . VAL B 1 481 ? 114.742 151.137 120.308 1.00 52.51  ? 481 VAL A O   1 
ATOM   7099 C  CB  . VAL B 1 481 ? 116.133 151.160 117.257 1.00 52.51  ? 481 VAL A CB  1 
ATOM   7100 C  CG1 . VAL B 1 481 ? 116.970 150.284 118.155 1.00 52.51  ? 481 VAL A CG1 1 
ATOM   7101 C  CG2 . VAL B 1 481 ? 115.926 150.484 115.920 1.00 52.51  ? 481 VAL A CG2 1 
ATOM   7102 N  N   . THR B 1 482 ? 115.343 153.177 119.567 1.00 53.92  ? 482 THR A N   1 
ATOM   7103 C  CA  . THR B 1 482 ? 115.526 153.683 120.923 1.00 53.92  ? 482 THR A CA  1 
ATOM   7104 C  C   . THR B 1 482 ? 114.216 153.677 121.695 1.00 53.92  ? 482 THR A C   1 
ATOM   7105 O  O   . THR B 1 482 ? 114.191 153.335 122.881 1.00 53.92  ? 482 THR A O   1 
ATOM   7106 C  CB  . THR B 1 482 ? 116.115 155.092 120.895 1.00 53.92  ? 482 THR A CB  1 
ATOM   7107 O  OG1 . THR B 1 482 ? 115.429 155.879 119.916 1.00 53.92  ? 482 THR A OG1 1 
ATOM   7108 C  CG2 . THR B 1 482 ? 117.591 155.046 120.560 1.00 53.92  ? 482 THR A CG2 1 
ATOM   7109 N  N   . SER B 1 483 ? 113.116 154.063 121.047 1.00 55.16  ? 483 SER A N   1 
ATOM   7110 C  CA  . SER B 1 483 ? 111.828 154.069 121.728 1.00 55.16  ? 483 SER A CA  1 
ATOM   7111 C  C   . SER B 1 483 ? 111.393 152.661 122.111 1.00 55.16  ? 483 SER A C   1 
ATOM   7112 O  O   . SER B 1 483 ? 110.875 152.447 123.212 1.00 55.16  ? 483 SER A O   1 
ATOM   7113 C  CB  . SER B 1 483 ? 110.774 154.739 120.849 1.00 55.16  ? 483 SER A CB  1 
ATOM   7114 O  OG  . SER B 1 483 ? 111.089 156.104 120.643 1.00 55.16  ? 483 SER A OG  1 
ATOM   7115 N  N   . LEU B 1 484 ? 111.593 151.684 121.223 1.00 51.79  ? 484 LEU A N   1 
ATOM   7116 C  CA  . LEU B 1 484 ? 111.145 150.334 121.539 1.00 51.79  ? 484 LEU A CA  1 
ATOM   7117 C  C   . LEU B 1 484 ? 112.006 149.702 122.625 1.00 51.79  ? 484 LEU A C   1 
ATOM   7118 O  O   . LEU B 1 484 ? 111.488 149.002 123.503 1.00 51.79  ? 484 LEU A O   1 
ATOM   7119 C  CB  . LEU B 1 484 ? 111.139 149.456 120.291 1.00 51.79  ? 484 LEU A CB  1 
ATOM   7120 C  CG  . LEU B 1 484 ? 110.555 148.075 120.603 1.00 51.79  ? 484 LEU A CG  1 
ATOM   7121 C  CD1 . LEU B 1 484 ? 109.186 148.214 121.261 1.00 51.79  ? 484 LEU A CD1 1 
ATOM   7122 C  CD2 . LEU B 1 484 ? 110.472 147.194 119.379 1.00 51.79  ? 484 LEU A CD2 1 
ATOM   7123 N  N   . THR B 1 485 ? 113.319 149.942 122.597 1.00 50.62  ? 485 THR A N   1 
ATOM   7124 C  CA  . THR B 1 485 ? 114.182 149.280 123.567 1.00 50.62  ? 485 THR A CA  1 
ATOM   7125 C  C   . THR B 1 485 ? 113.987 149.797 124.985 1.00 50.62  ? 485 THR A C   1 
ATOM   7126 O  O   . THR B 1 485 ? 114.538 149.205 125.918 1.00 50.62  ? 485 THR A O   1 
ATOM   7127 C  CB  . THR B 1 485 ? 115.652 149.421 123.170 1.00 50.62  ? 485 THR A CB  1 
ATOM   7128 O  OG1 . THR B 1 485 ? 116.454 148.613 124.040 1.00 50.62  ? 485 THR A OG1 1 
ATOM   7129 C  CG2 . THR B 1 485 ? 116.103 150.860 123.286 1.00 50.62  ? 485 THR A CG2 1 
ATOM   7130 N  N   . GLU B 1 486 ? 113.225 150.878 125.173 1.00 53.91  ? 486 GLU A N   1 
ATOM   7131 C  CA  . GLU B 1 486 ? 112.946 151.359 126.522 1.00 53.91  ? 486 GLU A CA  1 
ATOM   7132 C  C   . GLU B 1 486 ? 112.076 150.381 127.298 1.00 53.91  ? 486 GLU A C   1 
ATOM   7133 O  O   . GLU B 1 486 ? 112.214 150.267 128.520 1.00 53.91  ? 486 GLU A O   1 
ATOM   7134 C  CB  . GLU B 1 486 ? 112.262 152.727 126.472 1.00 53.91  ? 486 GLU A CB  1 
ATOM   7135 C  CG  . GLU B 1 486 ? 112.980 153.793 125.656 1.00 53.91  ? 486 GLU A CG  1 
ATOM   7136 C  CD  . GLU B 1 486 ? 114.333 154.217 126.212 1.00 53.91  ? 486 GLU A CD  1 
ATOM   7137 O  OE1 . GLU B 1 486 ? 114.883 153.543 127.106 1.00 53.91  ? 486 GLU A OE1 1 
ATOM   7138 O  OE2 . GLU B 1 486 ? 114.864 155.236 125.725 1.00 53.91  ? 486 GLU A OE2 1 
ATOM   7139 N  N   . VAL B 1 487 ? 111.174 149.678 126.615 1.00 52.09  ? 487 VAL A N   1 
ATOM   7140 C  CA  . VAL B 1 487 ? 110.222 148.782 127.256 1.00 52.09  ? 487 VAL A CA  1 
ATOM   7141 C  C   . VAL B 1 487 ? 110.415 147.337 126.815 1.00 52.09  ? 487 VAL A C   1 
ATOM   7142 O  O   . VAL B 1 487 ? 109.582 146.482 127.129 1.00 52.09  ? 487 VAL A O   1 
ATOM   7143 C  CB  . VAL B 1 487 ? 108.777 149.239 127.006 1.00 52.09  ? 487 VAL A CB  1 
ATOM   7144 C  CG1 . VAL B 1 487 ? 108.572 150.650 127.528 1.00 52.09  ? 487 VAL A CG1 1 
ATOM   7145 C  CG2 . VAL B 1 487 ? 108.450 149.164 125.525 1.00 52.09  ? 487 VAL A CG2 1 
ATOM   7146 N  N   . ALA B 1 488 ? 111.492 147.039 126.094 1.00 51.70  ? 488 ALA A N   1 
ATOM   7147 C  CA  . ALA B 1 488 ? 111.755 145.686 125.631 1.00 51.70  ? 488 ALA A CA  1 
ATOM   7148 C  C   . ALA B 1 488 ? 113.230 145.366 125.820 1.00 51.70  ? 488 ALA A C   1 
ATOM   7149 O  O   . ALA B 1 488 ? 114.077 146.259 125.890 1.00 51.70  ? 488 ALA A O   1 
ATOM   7150 C  CB  . ALA B 1 488 ? 111.356 145.502 124.162 1.00 51.70  ? 488 ALA A CB  1 
ATOM   7151 N  N   . SER B 1 489 ? 113.526 144.074 125.910 1.00 53.21  ? 489 SER A N   1 
ATOM   7152 C  CA  . SER B 1 489 ? 114.907 143.635 126.042 1.00 53.21  ? 489 SER A CA  1 
ATOM   7153 C  C   . SER B 1 489 ? 115.683 143.938 124.767 1.00 53.21  ? 489 SER A C   1 
ATOM   7154 O  O   . SER B 1 489 ? 115.153 143.830 123.658 1.00 53.21  ? 489 SER A O   1 
ATOM   7155 C  CB  . SER B 1 489 ? 114.960 142.142 126.357 1.00 53.21  ? 489 SER A CB  1 
ATOM   7156 O  OG  . SER B 1 489 ? 114.378 141.383 125.313 1.00 53.21  ? 489 SER A OG  1 
ATOM   7157 N  N   . ASN B 1 490 ? 116.946 144.331 124.933 1.00 51.64  ? 490 ASN A N   1 
ATOM   7158 C  CA  . ASN B 1 490 ? 117.760 144.739 123.789 1.00 51.64  ? 490 ASN A CA  1 
ATOM   7159 C  C   . ASN B 1 490 ? 117.958 143.631 122.760 1.00 51.64  ? 490 ASN A C   1 
ATOM   7160 O  O   . ASN B 1 490 ? 117.811 143.909 121.555 1.00 51.64  ? 490 ASN A O   1 
ATOM   7161 C  CB  . ASN B 1 490 ? 119.102 145.282 124.287 1.00 51.64  ? 490 ASN A CB  1 
ATOM   7162 C  CG  . ASN B 1 490 ? 118.939 146.417 125.273 1.00 51.64  ? 490 ASN A CG  1 
ATOM   7163 O  OD1 . ASN B 1 490 ? 118.035 147.241 125.142 1.00 51.64  ? 490 ASN A OD1 1 
ATOM   7164 N  ND2 . ASN B 1 490 ? 119.814 146.466 126.270 1.00 51.64  ? 490 ASN A ND2 1 
ATOM   7165 N  N   . PRO B 1 491 ? 118.314 142.392 123.131 1.00 53.00  ? 491 PRO A N   1 
ATOM   7166 C  CA  . PRO B 1 491 ? 118.450 141.352 122.098 1.00 53.00  ? 491 PRO A CA  1 
ATOM   7167 C  C   . PRO B 1 491 ? 117.179 141.122 121.301 1.00 53.00  ? 491 PRO A C   1 
ATOM   7168 O  O   . PRO B 1 491 ? 117.244 140.931 120.080 1.00 53.00  ? 491 PRO A O   1 
ATOM   7169 C  CB  . PRO B 1 491 ? 118.855 140.106 122.901 1.00 53.00  ? 491 PRO A CB  1 
ATOM   7170 C  CG  . PRO B 1 491 ? 118.537 140.419 124.316 1.00 53.00  ? 491 PRO A CG  1 
ATOM   7171 C  CD  . PRO B 1 491 ? 118.710 141.887 124.457 1.00 53.00  ? 491 PRO A CD  1 
ATOM   7172 N  N   . ALA B 1 492 ? 116.016 141.157 121.955 1.00 50.75  ? 492 ALA A N   1 
ATOM   7173 C  CA  . ALA B 1 492 ? 114.764 140.991 121.226 1.00 50.75  ? 492 ALA A CA  1 
ATOM   7174 C  C   . ALA B 1 492 ? 114.555 142.120 120.228 1.00 50.75  ? 492 ALA A C   1 
ATOM   7175 O  O   . ALA B 1 492 ? 114.178 141.878 119.076 1.00 50.75  ? 492 ALA A O   1 
ATOM   7176 C  CB  . ALA B 1 492 ? 113.592 140.916 122.202 1.00 50.75  ? 492 ALA A CB  1 
ATOM   7177 N  N   . THR B 1 493 ? 114.816 143.360 120.643 1.00 50.31  ? 493 THR A N   1 
ATOM   7178 C  CA  . THR B 1 493 ? 114.630 144.494 119.745 1.00 50.31  ? 493 THR A CA  1 
ATOM   7179 C  C   . THR B 1 493 ? 115.559 144.407 118.542 1.00 50.31  ? 493 THR A C   1 
ATOM   7180 O  O   . THR B 1 493 ? 115.136 144.640 117.399 1.00 50.31  ? 493 THR A O   1 
ATOM   7181 C  CB  . THR B 1 493 ? 114.859 145.802 120.499 1.00 50.31  ? 493 THR A CB  1 
ATOM   7182 O  OG1 . THR B 1 493 ? 113.967 145.870 121.617 1.00 50.31  ? 493 THR A OG1 1 
ATOM   7183 C  CG2 . THR B 1 493 ? 114.612 146.989 119.589 1.00 50.31  ? 493 THR A CG2 1 
ATOM   7184 N  N   . ILE B 1 494 ? 116.829 144.070 118.773 1.00 51.53  ? 494 ILE A N   1 
ATOM   7185 C  CA  . ILE B 1 494 ? 117.768 144.031 117.659 1.00 51.53  ? 494 ILE A CA  1 
ATOM   7186 C  C   . ILE B 1 494 ? 117.435 142.878 116.718 1.00 51.53  ? 494 ILE A C   1 
ATOM   7187 O  O   . ILE B 1 494 ? 117.463 143.042 115.493 1.00 51.53  ? 494 ILE A O   1 
ATOM   7188 C  CB  . ILE B 1 494 ? 119.225 143.977 118.161 1.00 51.53  ? 494 ILE A CB  1 
ATOM   7189 C  CG1 . ILE B 1 494 ? 120.190 144.163 116.991 1.00 51.53  ? 494 ILE A CG1 1 
ATOM   7190 C  CG2 . ILE B 1 494 ? 119.525 142.689 118.895 1.00 51.53  ? 494 ILE A CG2 1 
ATOM   7191 C  CD1 . ILE B 1 494 ? 120.041 145.491 116.291 1.00 51.53  ? 494 ILE A CD1 1 
ATOM   7192 N  N   . THR B 1 495 ? 117.076 141.709 117.259 1.00 49.22  ? 495 THR A N   1 
ATOM   7193 C  CA  . THR B 1 495 ? 116.728 140.594 116.389 1.00 49.22  ? 495 THR A CA  1 
ATOM   7194 C  C   . THR B 1 495 ? 115.379 140.793 115.714 1.00 49.22  ? 495 THR A C   1 
ATOM   7195 O  O   . THR B 1 495 ? 115.077 140.093 114.743 1.00 49.22  ? 495 THR A O   1 
ATOM   7196 C  CB  . THR B 1 495 ? 116.728 139.282 117.171 1.00 49.22  ? 495 THR A CB  1 
ATOM   7197 O  OG1 . THR B 1 495 ? 116.809 138.183 116.256 1.00 49.22  ? 495 THR A OG1 1 
ATOM   7198 C  CG2 . THR B 1 495 ? 115.460 139.148 117.986 1.00 49.22  ? 495 THR A CG2 1 
ATOM   7199 N  N   . LEU B 1 496 ? 114.562 141.725 116.206 1.00 50.00  ? 496 LEU A N   1 
ATOM   7200 C  CA  . LEU B 1 496 ? 113.288 141.996 115.557 1.00 50.00  ? 496 LEU A CA  1 
ATOM   7201 C  C   . LEU B 1 496 ? 113.433 143.016 114.434 1.00 50.00  ? 496 LEU A C   1 
ATOM   7202 O  O   . LEU B 1 496 ? 112.765 142.899 113.402 1.00 50.00  ? 496 LEU A O   1 
ATOM   7203 C  CB  . LEU B 1 496 ? 112.274 142.482 116.592 1.00 50.00  ? 496 LEU A CB  1 
ATOM   7204 C  CG  . LEU B 1 496 ? 110.796 142.282 116.272 1.00 50.00  ? 496 LEU A CG  1 
ATOM   7205 C  CD1 . LEU B 1 496 ? 110.499 140.810 116.061 1.00 50.00  ? 496 LEU A CD1 1 
ATOM   7206 C  CD2 . LEU B 1 496 ? 109.942 142.848 117.390 1.00 50.00  ? 496 LEU A CD2 1 
ATOM   7207 N  N   . PHE B 1 497 ? 114.293 144.022 114.609 1.00 53.73  ? 497 PHE A N   1 
ATOM   7208 C  CA  . PHE B 1 497 ? 114.424 145.052 113.581 1.00 53.73  ? 497 PHE A CA  1 
ATOM   7209 C  C   . PHE B 1 497 ? 115.539 144.815 112.571 1.00 53.73  ? 497 PHE A C   1 
ATOM   7210 O  O   . PHE B 1 497 ? 115.424 145.285 111.434 1.00 53.73  ? 497 PHE A O   1 
ATOM   7211 C  CB  . PHE B 1 497 ? 114.613 146.435 114.209 1.00 53.73  ? 497 PHE A CB  1 
ATOM   7212 C  CG  . PHE B 1 497 ? 113.398 146.955 114.912 1.00 53.73  ? 497 PHE A CG  1 
ATOM   7213 C  CD1 . PHE B 1 497 ? 112.160 146.369 114.707 1.00 53.73  ? 497 PHE A CD1 1 
ATOM   7214 C  CD2 . PHE B 1 497 ? 113.481 148.055 115.741 1.00 53.73  ? 497 PHE A CD2 1 
ATOM   7215 C  CE1 . PHE B 1 497 ? 111.035 146.859 115.336 1.00 53.73  ? 497 PHE A CE1 1 
ATOM   7216 C  CE2 . PHE B 1 497 ? 112.360 148.548 116.373 1.00 53.73  ? 497 PHE A CE2 1 
ATOM   7217 C  CZ  . PHE B 1 497 ? 111.137 147.948 116.169 1.00 53.73  ? 497 PHE A CZ  1 
ATOM   7218 N  N   . LEU B 1 498 ? 116.614 144.120 112.935 1.00 52.14  ? 498 LEU A N   1 
ATOM   7219 C  CA  . LEU B 1 498 ? 117.727 143.957 112.002 1.00 52.14  ? 498 LEU A CA  1 
ATOM   7220 C  C   . LEU B 1 498 ? 117.328 143.214 110.729 1.00 52.14  ? 498 LEU A C   1 
ATOM   7221 O  O   . LEU B 1 498 ? 117.668 143.691 109.629 1.00 52.14  ? 498 LEU A O   1 
ATOM   7222 C  CB  . LEU B 1 498 ? 118.889 143.285 112.742 1.00 52.14  ? 498 LEU A CB  1 
ATOM   7223 C  CG  . LEU B 1 498 ? 120.226 143.071 112.048 1.00 52.14  ? 498 LEU A CG  1 
ATOM   7224 C  CD1 . LEU B 1 498 ? 120.827 144.406 111.689 1.00 52.14  ? 498 LEU A CD1 1 
ATOM   7225 C  CD2 . LEU B 1 498 ? 121.146 142.326 112.985 1.00 52.14  ? 498 LEU A CD2 1 
ATOM   7226 N  N   . PRO B 1 499 ? 116.611 142.081 110.783 1.00 52.19  ? 499 PRO A N   1 
ATOM   7227 C  CA  . PRO B 1 499 ? 116.160 141.443 109.536 1.00 52.19  ? 499 PRO A CA  1 
ATOM   7228 C  C   . PRO B 1 499 ? 115.127 142.248 108.772 1.00 52.19  ? 499 PRO A C   1 
ATOM   7229 O  O   . PRO B 1 499 ? 114.759 141.846 107.662 1.00 52.19  ? 499 PRO A O   1 
ATOM   7230 C  CB  . PRO B 1 499 ? 115.570 140.109 110.013 1.00 52.19  ? 499 PRO A CB  1 
ATOM   7231 C  CG  . PRO B 1 499 ? 116.164 139.882 111.349 1.00 52.19  ? 499 PRO A CG  1 
ATOM   7232 C  CD  . PRO B 1 499 ? 116.290 141.241 111.949 1.00 52.19  ? 499 PRO A CD  1 
ATOM   7233 N  N   . ILE B 1 500 ? 114.625 143.342 109.335 1.00 53.34  ? 500 ILE A N   1 
ATOM   7234 C  CA  . ILE B 1 500 ? 113.762 144.253 108.591 1.00 53.34  ? 500 ILE A CA  1 
ATOM   7235 C  C   . ILE B 1 500 ? 114.564 145.407 108.008 1.00 53.34  ? 500 ILE A C   1 
ATOM   7236 O  O   . ILE B 1 500 ? 114.314 145.839 106.881 1.00 53.34  ? 500 ILE A O   1 
ATOM   7237 C  CB  . ILE B 1 500 ? 112.622 144.756 109.498 1.00 53.34  ? 500 ILE A CB  1 
ATOM   7238 C  CG1 . ILE B 1 500 ? 111.712 143.595 109.901 1.00 53.34  ? 500 ILE A CG1 1 
ATOM   7239 C  CG2 . ILE B 1 500 ? 111.822 145.848 108.807 1.00 53.34  ? 500 ILE A CG2 1 
ATOM   7240 C  CD1 . ILE B 1 500 ? 110.664 143.967 110.924 1.00 53.34  ? 500 ILE A CD1 1 
ATOM   7241 N  N   . LEU B 1 501 ? 115.540 145.911 108.765 1.00 57.36  ? 501 LEU A N   1 
ATOM   7242 C  CA  . LEU B 1 501 ? 116.357 147.019 108.283 1.00 57.36  ? 501 LEU A CA  1 
ATOM   7243 C  C   . LEU B 1 501 ? 117.245 146.595 107.121 1.00 57.36  ? 501 LEU A C   1 
ATOM   7244 O  O   . LEU B 1 501 ? 117.449 147.371 106.179 1.00 57.36  ? 501 LEU A O   1 
ATOM   7245 C  CB  . LEU B 1 501 ? 117.202 147.584 109.423 1.00 57.36  ? 501 LEU A CB  1 
ATOM   7246 C  CG  . LEU B 1 501 ? 116.456 148.416 110.465 1.00 57.36  ? 501 LEU A CG  1 
ATOM   7247 C  CD1 . LEU B 1 501 ? 117.321 148.627 111.693 1.00 57.36  ? 501 LEU A CD1 1 
ATOM   7248 C  CD2 . LEU B 1 501 ? 116.023 149.746 109.875 1.00 57.36  ? 501 LEU A CD2 1 
ATOM   7249 N  N   . SER B 1 502 ? 117.793 145.378 107.168 1.00 59.81  ? 502 SER A N   1 
ATOM   7250 C  CA  . SER B 1 502 ? 118.713 144.958 106.111 1.00 59.81  ? 502 SER A CA  1 
ATOM   7251 C  C   . SER B 1 502 ? 118.074 144.952 104.724 1.00 59.81  ? 502 SER A C   1 
ATOM   7252 O  O   . SER B 1 502 ? 118.680 145.511 103.791 1.00 59.81  ? 502 SER A O   1 
ATOM   7253 C  CB  . SER B 1 502 ? 119.313 143.593 106.463 1.00 59.81  ? 502 SER A CB  1 
ATOM   7254 O  OG  . SER B 1 502 ? 119.770 143.578 107.801 1.00 59.81  ? 502 SER A OG  1 
ATOM   7255 N  N   . PRO B 1 503 ? 116.894 144.354 104.503 1.00 61.79  ? 503 PRO A N   1 
ATOM   7256 C  CA  . PRO B 1 503 ? 116.276 144.472 103.171 1.00 61.79  ? 503 PRO A CA  1 
ATOM   7257 C  C   . PRO B 1 503 ? 115.968 145.905 102.783 1.00 61.79  ? 503 PRO A C   1 
ATOM   7258 O  O   . PRO B 1 503 ? 116.083 146.261 101.605 1.00 61.79  ? 503 PRO A O   1 
ATOM   7259 C  CB  . PRO B 1 503 ? 114.999 143.630 103.301 1.00 61.79  ? 503 PRO A CB  1 
ATOM   7260 C  CG  . PRO B 1 503 ? 115.267 142.707 104.431 1.00 61.79  ? 503 PRO A CG  1 
ATOM   7261 C  CD  . PRO B 1 503 ? 116.087 143.501 105.390 1.00 61.79  ? 503 PRO A CD  1 
ATOM   7262 N  N   . LEU B 1 504 ? 115.580 146.742 103.748 1.00 64.58  ? 504 LEU A N   1 
ATOM   7263 C  CA  . LEU B 1 504 ? 115.376 148.157 103.456 1.00 64.58  ? 504 LEU A CA  1 
ATOM   7264 C  C   . LEU B 1 504 ? 116.681 148.820 103.046 1.00 64.58  ? 504 LEU A C   1 
ATOM   7265 O  O   . LEU B 1 504 ? 116.701 149.666 102.144 1.00 64.58  ? 504 LEU A O   1 
ATOM   7266 C  CB  . LEU B 1 504 ? 114.775 148.865 104.669 1.00 64.58  ? 504 LEU A CB  1 
ATOM   7267 C  CG  . LEU B 1 504 ? 114.453 150.346 104.473 1.00 64.58  ? 504 LEU A CG  1 
ATOM   7268 C  CD1 . LEU B 1 504 ? 113.402 150.523 103.394 1.00 64.58  ? 504 LEU A CD1 1 
ATOM   7269 C  CD2 . LEU B 1 504 ? 113.992 150.971 105.777 1.00 64.58  ? 504 LEU A CD2 1 
ATOM   7270 N  N   . ALA B 1 505 ? 117.782 148.453 103.704 1.00 68.15  ? 505 ALA A N   1 
ATOM   7271 C  CA  . ALA B 1 505 ? 119.083 148.996 103.332 1.00 68.15  ? 505 ALA A CA  1 
ATOM   7272 C  C   . ALA B 1 505 ? 119.457 148.599 101.912 1.00 68.15  ? 505 ALA A C   1 
ATOM   7273 O  O   . ALA B 1 505 ? 119.962 149.423 101.141 1.00 68.15  ? 505 ALA A O   1 
ATOM   7274 C  CB  . ALA B 1 505 ? 120.149 148.524 104.318 1.00 68.15  ? 505 ALA A CB  1 
ATOM   7275 N  N   . GLU B 1 506 ? 119.216 147.339 101.546 1.00 69.70  ? 506 GLU A N   1 
ATOM   7276 C  CA  . GLU B 1 506 ? 119.554 146.891 100.200 1.00 69.70  ? 506 GLU A CA  1 
ATOM   7277 C  C   . GLU B 1 506 ? 118.599 147.437 99.145  1.00 69.70  ? 506 GLU A C   1 
ATOM   7278 O  O   . GLU B 1 506 ? 118.978 147.524 97.973  1.00 69.70  ? 506 GLU A O   1 
ATOM   7279 C  CB  . GLU B 1 506 ? 119.578 145.364 100.142 1.00 69.70  ? 506 GLU A CB  1 
ATOM   7280 C  CG  . GLU B 1 506 ? 120.592 144.729 101.077 1.00 69.70  ? 506 GLU A CG  1 
ATOM   7281 C  CD  . GLU B 1 506 ? 120.471 143.219 101.131 1.00 69.70  ? 506 GLU A CD  1 
ATOM   7282 O  OE1 . GLU B 1 506 ? 119.676 142.657 100.350 1.00 69.70  ? 506 GLU A OE1 1 
ATOM   7283 O  OE2 . GLU B 1 506 ? 121.170 142.594 101.956 1.00 69.70  ? 506 GLU A OE2 1 
ATOM   7284 N  N   . ALA B 1 507 ? 117.375 147.804 99.530  1.00 70.78  ? 507 ALA A N   1 
ATOM   7285 C  CA  . ALA B 1 507 ? 116.402 148.285 98.556  1.00 70.78  ? 507 ALA A CA  1 
ATOM   7286 C  C   . ALA B 1 507 ? 116.706 149.707 98.098  1.00 70.78  ? 507 ALA A C   1 
ATOM   7287 O  O   . ALA B 1 507 ? 116.552 150.025 96.914  1.00 70.78  ? 507 ALA A O   1 
ATOM   7288 C  CB  . ALA B 1 507 ? 114.992 148.208 99.141  1.00 70.78  ? 507 ALA A CB  1 
ATOM   7289 N  N   . ILE B 1 508 ? 117.138 150.576 99.018  1.00 72.27  ? 508 ILE A N   1 
ATOM   7290 C  CA  . ILE B 1 508 ? 117.389 151.975 98.686  1.00 72.27  ? 508 ILE A CA  1 
ATOM   7291 C  C   . ILE B 1 508 ? 118.734 152.164 97.991  1.00 72.27  ? 508 ILE A C   1 
ATOM   7292 O  O   . ILE B 1 508 ? 119.082 153.293 97.616  1.00 72.27  ? 508 ILE A O   1 
ATOM   7293 C  CB  . ILE B 1 508 ? 117.270 152.823 99.973  1.00 72.27  ? 508 ILE A CB  1 
ATOM   7294 C  CG1 . ILE B 1 508 ? 115.949 152.518 100.674 1.00 72.27  ? 508 ILE A CG1 1 
ATOM   7295 C  CG2 . ILE B 1 508 ? 117.269 154.314 99.673  1.00 72.27  ? 508 ILE A CG2 1 
ATOM   7296 C  CD1 . ILE B 1 508 ? 115.824 153.150 102.041 1.00 72.27  ? 508 ILE A CD1 1 
ATOM   7297 N  N   . HIS B 1 509 ? 119.489 151.084 97.779  1.00 70.95  ? 509 HIS A N   1 
ATOM   7298 C  CA  . HIS B 1 509 ? 120.805 151.134 97.142  1.00 70.95  ? 509 HIS A CA  1 
ATOM   7299 C  C   . HIS B 1 509 ? 121.759 152.014 97.956  1.00 70.95  ? 509 HIS A C   1 
ATOM   7300 O  O   . HIS B 1 509 ? 122.337 152.987 97.468  1.00 70.95  ? 509 HIS A O   1 
ATOM   7301 C  CB  . HIS B 1 509 ? 120.696 151.607 95.687  1.00 70.95  ? 509 HIS A CB  1 
ATOM   7302 C  CG  . HIS B 1 509 ? 122.002 151.623 94.954  1.00 70.95  ? 509 HIS A CG  1 
ATOM   7303 N  ND1 . HIS B 1 509 ? 122.977 150.669 95.149  1.00 70.95  ? 509 HIS A ND1 1 
ATOM   7304 C  CD2 . HIS B 1 509 ? 122.495 152.481 94.030  1.00 70.95  ? 509 HIS A CD2 1 
ATOM   7305 C  CE1 . HIS B 1 509 ? 124.013 150.936 94.375  1.00 70.95  ? 509 HIS A CE1 1 
ATOM   7306 N  NE2 . HIS B 1 509 ? 123.747 152.031 93.686  1.00 70.95  ? 509 HIS A NE2 1 
ATOM   7307 N  N   . VAL B 1 510 ? 121.895 151.653 99.231  1.00 69.54  ? 510 VAL A N   1 
ATOM   7308 C  CA  . VAL B 1 510 ? 122.792 152.327 100.157 1.00 69.54  ? 510 VAL A CA  1 
ATOM   7309 C  C   . VAL B 1 510 ? 123.568 151.260 100.916 1.00 69.54  ? 510 VAL A C   1 
ATOM   7310 O  O   . VAL B 1 510 ? 123.164 150.098 100.987 1.00 69.54  ? 510 VAL A O   1 
ATOM   7311 C  CB  . VAL B 1 510 ? 122.034 153.257 101.133 1.00 69.54  ? 510 VAL A CB  1 
ATOM   7312 C  CG1 . VAL B 1 510 ? 121.338 152.446 102.217 1.00 69.54  ? 510 VAL A CG1 1 
ATOM   7313 C  CG2 . VAL B 1 510 ? 122.968 154.300 101.733 1.00 69.54  ? 510 VAL A CG2 1 
ATOM   7314 N  N   . ASN B 1 511 ? 124.702 151.666 101.472 1.00 65.72  ? 511 ASN A N   1 
ATOM   7315 C  CA  . ASN B 1 511 ? 125.536 150.737 102.219 1.00 65.72  ? 511 ASN A CA  1 
ATOM   7316 C  C   . ASN B 1 511 ? 124.753 150.190 103.409 1.00 65.72  ? 511 ASN A C   1 
ATOM   7317 O  O   . ASN B 1 511 ? 124.220 150.974 104.205 1.00 65.72  ? 511 ASN A O   1 
ATOM   7318 C  CB  . ASN B 1 511 ? 126.808 151.437 102.696 1.00 65.72  ? 511 ASN A CB  1 
ATOM   7319 C  CG  . ASN B 1 511 ? 127.965 150.480 102.890 1.00 65.72  ? 511 ASN A CG  1 
ATOM   7320 O  OD1 . ASN B 1 511 ? 127.772 149.313 103.225 1.00 65.72  ? 511 ASN A OD1 1 
ATOM   7321 N  ND2 . ASN B 1 511 ? 129.180 150.971 102.679 1.00 65.72  ? 511 ASN A ND2 1 
ATOM   7322 N  N   . PRO B 1 512 ? 124.641 148.868 103.554 1.00 61.87  ? 512 PRO A N   1 
ATOM   7323 C  CA  . PRO B 1 512 ? 123.901 148.322 104.703 1.00 61.87  ? 512 PRO A CA  1 
ATOM   7324 C  C   . PRO B 1 512 ? 124.448 148.772 106.044 1.00 61.87  ? 512 PRO A C   1 
ATOM   7325 O  O   . PRO B 1 512 ? 123.667 148.981 106.980 1.00 61.87  ? 512 PRO A O   1 
ATOM   7326 C  CB  . PRO B 1 512 ? 124.038 146.805 104.516 1.00 61.87  ? 512 PRO A CB  1 
ATOM   7327 C  CG  . PRO B 1 512 ? 124.256 146.626 103.056 1.00 61.87  ? 512 PRO A CG  1 
ATOM   7328 C  CD  . PRO B 1 512 ? 125.047 147.818 102.605 1.00 61.87  ? 512 PRO A CD  1 
ATOM   7329 N  N   . LEU B 1 513 ? 125.768 148.939 106.163 1.00 61.00  ? 513 LEU A N   1 
ATOM   7330 C  CA  . LEU B 1 513 ? 126.343 149.422 107.414 1.00 61.00  ? 513 LEU A CA  1 
ATOM   7331 C  C   . LEU B 1 513 ? 125.805 150.797 107.776 1.00 61.00  ? 513 LEU A C   1 
ATOM   7332 O  O   . LEU B 1 513 ? 125.548 151.076 108.952 1.00 61.00  ? 513 LEU A O   1 
ATOM   7333 C  CB  . LEU B 1 513 ? 127.867 149.452 107.316 1.00 61.00  ? 513 LEU A CB  1 
ATOM   7334 C  CG  . LEU B 1 513 ? 128.568 148.103 107.209 1.00 61.00  ? 513 LEU A CG  1 
ATOM   7335 C  CD1 . LEU B 1 513 ? 129.993 148.214 107.706 1.00 61.00  ? 513 LEU A CD1 1 
ATOM   7336 C  CD2 . LEU B 1 513 ? 127.813 147.093 108.039 1.00 61.00  ? 513 LEU A CD2 1 
ATOM   7337 N  N   . TYR B 1 514 ? 125.613 151.662 106.776 1.00 61.04  ? 514 TYR A N   1 
ATOM   7338 C  CA  . TYR B 1 514 ? 125.087 152.998 107.031 1.00 61.04  ? 514 TYR A CA  1 
ATOM   7339 C  C   . TYR B 1 514 ? 123.766 152.946 107.783 1.00 61.04  ? 514 TYR A C   1 
ATOM   7340 O  O   . TYR B 1 514 ? 123.506 153.800 108.636 1.00 61.04  ? 514 TYR A O   1 
ATOM   7341 C  CB  . TYR B 1 514 ? 124.921 153.748 105.710 1.00 61.04  ? 514 TYR A CB  1 
ATOM   7342 C  CG  . TYR B 1 514 ? 124.652 155.225 105.857 1.00 61.04  ? 514 TYR A CG  1 
ATOM   7343 C  CD1 . TYR B 1 514 ? 125.677 156.109 106.159 1.00 61.04  ? 514 TYR A CD1 1 
ATOM   7344 C  CD2 . TYR B 1 514 ? 123.378 155.738 105.677 1.00 61.04  ? 514 TYR A CD2 1 
ATOM   7345 C  CE1 . TYR B 1 514 ? 125.438 157.462 106.287 1.00 61.04  ? 514 TYR A CE1 1 
ATOM   7346 C  CE2 . TYR B 1 514 ? 123.128 157.090 105.803 1.00 61.04  ? 514 TYR A CE2 1 
ATOM   7347 C  CZ  . TYR B 1 514 ? 124.162 157.947 106.108 1.00 61.04  ? 514 TYR A CZ  1 
ATOM   7348 O  OH  . TYR B 1 514 ? 123.918 159.295 106.235 1.00 61.04  ? 514 TYR A OH  1 
ATOM   7349 N  N   . ILE B 1 515 ? 122.933 151.950 107.498 1.00 58.90  ? 515 ILE A N   1 
ATOM   7350 C  CA  . ILE B 1 515 ? 121.677 151.769 108.219 1.00 58.90  ? 515 ILE A CA  1 
ATOM   7351 C  C   . ILE B 1 515 ? 121.898 151.052 109.546 1.00 58.90  ? 515 ILE A C   1 
ATOM   7352 O  O   . ILE B 1 515 ? 121.363 151.465 110.577 1.00 58.90  ? 515 ILE A O   1 
ATOM   7353 C  CB  . ILE B 1 515 ? 120.673 150.997 107.338 1.00 58.90  ? 515 ILE A CB  1 
ATOM   7354 C  CG1 . ILE B 1 515 ? 120.458 151.693 105.992 1.00 58.90  ? 515 ILE A CG1 1 
ATOM   7355 C  CG2 . ILE B 1 515 ? 119.347 150.842 108.060 1.00 58.90  ? 515 ILE A CG2 1 
ATOM   7356 C  CD1 . ILE B 1 515 ? 119.779 153.027 106.082 1.00 58.90  ? 515 ILE A CD1 1 
ATOM   7357 N  N   . LEU B 1 516 ? 122.690 149.976 109.535 1.00 56.77  ? 516 LEU A N   1 
ATOM   7358 C  CA  . LEU B 1 516 ? 122.730 149.067 110.677 1.00 56.77  ? 516 LEU A CA  1 
ATOM   7359 C  C   . LEU B 1 516 ? 123.511 149.647 111.852 1.00 56.77  ? 516 LEU A C   1 
ATOM   7360 O  O   . LEU B 1 516 ? 123.087 149.510 113.006 1.00 56.77  ? 516 LEU A O   1 
ATOM   7361 C  CB  . LEU B 1 516 ? 123.325 147.725 110.256 1.00 56.77  ? 516 LEU A CB  1 
ATOM   7362 C  CG  . LEU B 1 516 ? 122.607 146.983 109.128 1.00 56.77  ? 516 LEU A CG  1 
ATOM   7363 C  CD1 . LEU B 1 516 ? 123.069 145.539 109.054 1.00 56.77  ? 516 LEU A CD1 1 
ATOM   7364 C  CD2 . LEU B 1 516 ? 121.100 147.064 109.293 1.00 56.77  ? 516 LEU A CD2 1 
ATOM   7365 N  N   . ILE B 1 517 ? 124.660 150.277 111.591 1.00 55.78  ? 517 ILE A N   1 
ATOM   7366 C  CA  . ILE B 1 517 ? 125.525 150.724 112.686 1.00 55.78  ? 517 ILE A CA  1 
ATOM   7367 C  C   . ILE B 1 517 ? 124.840 151.735 113.599 1.00 55.78  ? 517 ILE A C   1 
ATOM   7368 O  O   . ILE B 1 517 ? 124.877 151.545 114.826 1.00 55.78  ? 517 ILE A O   1 
ATOM   7369 C  CB  . ILE B 1 517 ? 126.864 151.238 112.129 1.00 55.78  ? 517 ILE A CB  1 
ATOM   7370 C  CG1 . ILE B 1 517 ? 127.618 150.110 111.427 1.00 55.78  ? 517 ILE A CG1 1 
ATOM   7371 C  CG2 . ILE B 1 517 ? 127.706 151.833 113.238 1.00 55.78  ? 517 ILE A CG2 1 
ATOM   7372 C  CD1 . ILE B 1 517 ? 128.812 150.582 110.636 1.00 55.78  ? 517 ILE A CD1 1 
ATOM   7373 N  N   . PRO B 1 518 ? 124.224 152.816 113.099 1.00 55.44  ? 518 PRO A N   1 
ATOM   7374 C  CA  . PRO B 1 518 ? 123.504 153.702 114.029 1.00 55.44  ? 518 PRO A CA  1 
ATOM   7375 C  C   . PRO B 1 518 ? 122.404 152.985 114.787 1.00 55.44  ? 518 PRO A C   1 
ATOM   7376 O  O   . PRO B 1 518 ? 122.241 153.208 115.991 1.00 55.44  ? 518 PRO A O   1 
ATOM   7377 C  CB  . PRO B 1 518 ? 122.938 154.810 113.130 1.00 55.44  ? 518 PRO A CB  1 
ATOM   7378 C  CG  . PRO B 1 518 ? 123.492 154.609 111.795 1.00 55.44  ? 518 PRO A CG  1 
ATOM   7379 C  CD  . PRO B 1 518 ? 124.178 153.298 111.707 1.00 55.44  ? 518 PRO A CD  1 
ATOM   7380 N  N   . SER B 1 519 ? 121.661 152.102 114.117 1.00 51.80  ? 519 SER A N   1 
ATOM   7381 C  CA  . SER B 1 519 ? 120.595 151.372 114.794 1.00 51.80  ? 519 SER A CA  1 
ATOM   7382 C  C   . SER B 1 519 ? 121.153 150.415 115.838 1.00 51.80  ? 519 SER A C   1 
ATOM   7383 O  O   . SER B 1 519 ? 120.614 150.315 116.946 1.00 51.80  ? 519 SER A O   1 
ATOM   7384 C  CB  . SER B 1 519 ? 119.748 150.617 113.773 1.00 51.80  ? 519 SER A CB  1 
ATOM   7385 O  OG  . SER B 1 519 ? 118.779 149.814 114.420 1.00 51.80  ? 519 SER A OG  1 
ATOM   7386 N  N   . THR B 1 520 ? 122.232 149.703 115.506 1.00 51.72  ? 520 THR A N   1 
ATOM   7387 C  CA  . THR B 1 520 ? 122.827 148.780 116.466 1.00 51.72  ? 520 THR A CA  1 
ATOM   7388 C  C   . THR B 1 520 ? 123.361 149.519 117.686 1.00 51.72  ? 520 THR A C   1 
ATOM   7389 O  O   . THR B 1 520 ? 123.187 149.063 118.822 1.00 51.72  ? 520 THR A O   1 
ATOM   7390 C  CB  . THR B 1 520 ? 123.941 147.972 115.803 1.00 51.72  ? 520 THR A CB  1 
ATOM   7391 O  OG1 . THR B 1 520 ? 123.423 147.309 114.644 1.00 51.72  ? 520 THR A OG1 1 
ATOM   7392 C  CG2 . THR B 1 520 ? 124.489 146.939 116.767 1.00 51.72  ? 520 THR A CG2 1 
ATOM   7393 N  N   . LEU B 1 521 ? 124.020 150.659 117.472 1.00 48.85  ? 521 LEU A N   1 
ATOM   7394 C  CA  . LEU B 1 521 ? 124.506 151.446 118.600 1.00 48.85  ? 521 LEU A CA  1 
ATOM   7395 C  C   . LEU B 1 521 ? 123.353 151.982 119.437 1.00 48.85  ? 521 LEU A C   1 
ATOM   7396 O  O   . LEU B 1 521 ? 123.406 151.949 120.671 1.00 48.85  ? 521 LEU A O   1 
ATOM   7397 C  CB  . LEU B 1 521 ? 125.384 152.593 118.103 1.00 48.85  ? 521 LEU A CB  1 
ATOM   7398 C  CG  . LEU B 1 521 ? 126.782 152.217 117.620 1.00 48.85  ? 521 LEU A CG  1 
ATOM   7399 C  CD1 . LEU B 1 521 ? 127.560 153.462 117.236 1.00 48.85  ? 521 LEU A CD1 1 
ATOM   7400 C  CD2 . LEU B 1 521 ? 127.517 151.432 118.687 1.00 48.85  ? 521 LEU A CD2 1 
ATOM   7401 N  N   . CYS B 1 522 ? 122.296 152.472 118.786 1.00 51.31  ? 522 CYS A N   1 
ATOM   7402 C  CA  . CYS B 1 522 ? 121.179 153.060 119.510 1.00 51.31  ? 522 CYS A CA  1 
ATOM   7403 C  C   . CYS B 1 522 ? 120.322 152.016 120.210 1.00 51.31  ? 522 CYS A C   1 
ATOM   7404 O  O   . CYS B 1 522 ? 119.546 152.372 121.103 1.00 51.31  ? 522 CYS A O   1 
ATOM   7405 C  CB  . CYS B 1 522 ? 120.318 153.883 118.554 1.00 51.31  ? 522 CYS A CB  1 
ATOM   7406 S  SG  . CYS B 1 522 ? 120.973 155.525 118.196 1.00 51.31  ? 522 CYS A SG  1 
ATOM   7407 N  N   . THR B 1 523 ? 120.433 150.744 119.821 1.00 49.16  ? 523 THR A N   1 
ATOM   7408 C  CA  . THR B 1 523 ? 119.653 149.705 120.484 1.00 49.16  ? 523 THR A CA  1 
ATOM   7409 C  C   . THR B 1 523 ? 119.994 149.615 121.965 1.00 49.16  ? 523 THR A C   1 
ATOM   7410 O  O   . THR B 1 523 ? 119.103 149.459 122.807 1.00 49.16  ? 523 THR A O   1 
ATOM   7411 C  CB  . THR B 1 523 ? 119.885 148.356 119.806 1.00 49.16  ? 523 THR A CB  1 
ATOM   7412 O  OG1 . THR B 1 523 ? 119.569 148.457 118.413 1.00 49.16  ? 523 THR A OG1 1 
ATOM   7413 C  CG2 . THR B 1 523 ? 119.009 147.289 120.438 1.00 49.16  ? 523 THR A CG2 1 
ATOM   7414 N  N   . SER B 1 524 ? 121.281 149.717 122.303 1.00 45.86  ? 524 SER A N   1 
ATOM   7415 C  CA  . SER B 1 524 ? 121.693 149.623 123.697 1.00 45.86  ? 524 SER A CA  1 
ATOM   7416 C  C   . SER B 1 524 ? 121.261 150.831 124.516 1.00 45.86  ? 524 SER A C   1 
ATOM   7417 O  O   . SER B 1 524 ? 121.323 150.779 125.748 1.00 45.86  ? 524 SER A O   1 
ATOM   7418 C  CB  . SER B 1 524 ? 123.209 149.456 123.786 1.00 45.86  ? 524 SER A CB  1 
ATOM   7419 O  OG  . SER B 1 524 ? 123.660 148.421 122.932 1.00 45.86  ? 524 SER A OG  1 
ATOM   7420 N  N   . PHE B 1 525 ? 120.828 151.911 123.871 1.00 46.95  ? 525 PHE A N   1 
ATOM   7421 C  CA  . PHE B 1 525 ? 120.401 153.111 124.587 1.00 46.95  ? 525 PHE A CA  1 
ATOM   7422 C  C   . PHE B 1 525 ? 118.982 152.884 125.090 1.00 46.95  ? 525 PHE A C   1 
ATOM   7423 O  O   . PHE B 1 525 ? 117.998 153.243 124.443 1.00 46.95  ? 525 PHE A O   1 
ATOM   7424 C  CB  . PHE B 1 525 ? 120.499 154.342 123.695 1.00 46.95  ? 525 PHE A CB  1 
ATOM   7425 C  CG  . PHE B 1 525 ? 121.905 154.685 123.296 1.00 46.95  ? 525 PHE A CG  1 
ATOM   7426 C  CD1 . PHE B 1 525 ? 122.980 154.218 124.032 1.00 46.95  ? 525 PHE A CD1 1 
ATOM   7427 C  CD2 . PHE B 1 525 ? 122.153 155.475 122.189 1.00 46.95  ? 525 PHE A CD2 1 
ATOM   7428 C  CE1 . PHE B 1 525 ? 124.274 154.528 123.669 1.00 46.95  ? 525 PHE A CE1 1 
ATOM   7429 C  CE2 . PHE B 1 525 ? 123.446 155.789 121.822 1.00 46.95  ? 525 PHE A CE2 1 
ATOM   7430 C  CZ  . PHE B 1 525 ? 124.508 155.315 122.563 1.00 46.95  ? 525 PHE A CZ  1 
ATOM   7431 N  N   . ALA B 1 526 ? 118.888 152.285 126.272 1.00 51.82  ? 526 ALA A N   1 
ATOM   7432 C  CA  . ALA B 1 526 ? 117.631 151.929 126.918 1.00 51.82  ? 526 ALA A CA  1 
ATOM   7433 C  C   . ALA B 1 526 ? 117.608 152.468 128.340 1.00 51.82  ? 526 ALA A C   1 
ATOM   7434 O  O   . ALA B 1 526 ? 117.332 151.754 129.306 1.00 51.82  ? 526 ALA A O   1 
ATOM   7435 C  CB  . ALA B 1 526 ? 117.426 150.419 126.908 1.00 51.82  ? 526 ALA A CB  1 
ATOM   7436 N  N   . PHE B 1 527 ? 117.910 153.756 128.483 1.00 51.13  ? 527 PHE A N   1 
ATOM   7437 C  CA  . PHE B 1 527 ? 118.246 154.329 129.784 1.00 51.13  ? 527 PHE A CA  1 
ATOM   7438 C  C   . PHE B 1 527 ? 117.031 154.866 130.529 1.00 51.13  ? 527 PHE A C   1 
ATOM   7439 O  O   . PHE B 1 527 ? 117.117 155.946 131.109 1.00 51.13  ? 527 PHE A O   1 
ATOM   7440 C  CB  . PHE B 1 527 ? 119.257 155.451 129.577 1.00 51.13  ? 527 PHE A CB  1 
ATOM   7441 C  CG  . PHE B 1 527 ? 120.589 154.992 129.065 1.00 51.13  ? 527 PHE A CG  1 
ATOM   7442 C  CD1 . PHE B 1 527 ? 121.529 154.453 129.911 1.00 51.13  ? 527 PHE A CD1 1 
ATOM   7443 C  CD2 . PHE B 1 527 ? 120.913 155.144 127.733 1.00 51.13  ? 527 PHE A CD2 1 
ATOM   7444 C  CE1 . PHE B 1 527 ? 122.754 154.054 129.437 1.00 51.13  ? 527 PHE A CE1 1 
ATOM   7445 C  CE2 . PHE B 1 527 ? 122.138 154.745 127.253 1.00 51.13  ? 527 PHE A CE2 1 
ATOM   7446 C  CZ  . PHE B 1 527 ? 123.059 154.194 128.103 1.00 51.13  ? 527 PHE A CZ  1 
ATOM   7447 N  N   . LEU B 1 528 ? 115.911 154.173 130.581 1.00 54.56  ? 528 LEU A N   1 
ATOM   7448 C  CA  . LEU B 1 528 ? 114.795 154.854 131.238 1.00 54.56  ? 528 LEU A CA  1 
ATOM   7449 C  C   . LEU B 1 528 ? 114.083 154.014 132.286 1.00 54.56  ? 528 LEU A C   1 
ATOM   7450 O  O   . LEU B 1 528 ? 113.694 154.551 133.325 1.00 54.56  ? 528 LEU A O   1 
ATOM   7451 C  CB  . LEU B 1 528 ? 113.765 155.355 130.206 1.00 54.56  ? 528 LEU A CB  1 
ATOM   7452 C  CG  . LEU B 1 528 ? 114.011 156.702 129.514 1.00 54.56  ? 528 LEU A CG  1 
ATOM   7453 C  CD1 . LEU B 1 528 ? 115.130 156.650 128.496 1.00 54.56  ? 528 LEU A CD1 1 
ATOM   7454 C  CD2 . LEU B 1 528 ? 112.728 157.206 128.868 1.00 54.56  ? 528 LEU A CD2 1 
ATOM   7455 N  N   . LEU B 1 529 ? 113.903 152.722 132.051 1.00 56.02  ? 529 LEU A N   1 
ATOM   7456 C  CA  . LEU B 1 529 ? 113.089 151.933 132.959 1.00 56.02  ? 529 LEU A CA  1 
ATOM   7457 C  C   . LEU B 1 529 ? 113.843 150.691 133.405 1.00 56.02  ? 529 LEU A C   1 
ATOM   7458 O  O   . LEU B 1 529 ? 114.707 150.187 132.682 1.00 56.02  ? 529 LEU A O   1 
ATOM   7459 C  CB  . LEU B 1 529 ? 111.765 151.523 132.298 1.00 56.02  ? 529 LEU A CB  1 
ATOM   7460 C  CG  . LEU B 1 529 ? 110.912 152.655 131.720 1.00 56.02  ? 529 LEU A CG  1 
ATOM   7461 C  CD1 . LEU B 1 529 ? 109.931 152.117 130.694 1.00 56.02  ? 529 LEU A CD1 1 
ATOM   7462 C  CD2 . LEU B 1 529 ? 110.179 153.399 132.823 1.00 56.02  ? 529 LEU A CD2 1 
ATOM   7463 N  N   . PRO B 1 530 ? 113.545 150.188 134.604 1.00 57.19  ? 530 PRO A N   1 
ATOM   7464 C  CA  . PRO B 1 530 ? 114.182 148.940 135.052 1.00 57.19  ? 530 PRO A CA  1 
ATOM   7465 C  C   . PRO B 1 530 ? 113.907 147.764 134.136 1.00 57.19  ? 530 PRO A C   1 
ATOM   7466 O  O   . PRO B 1 530 ? 114.749 146.865 134.026 1.00 57.19  ? 530 PRO A O   1 
ATOM   7467 C  CB  . PRO B 1 530 ? 113.578 148.725 136.447 1.00 57.19  ? 530 PRO A CB  1 
ATOM   7468 C  CG  . PRO B 1 530 ? 113.149 150.085 136.886 1.00 57.19  ? 530 PRO A CG  1 
ATOM   7469 C  CD  . PRO B 1 530 ? 112.693 150.782 135.646 1.00 57.19  ? 530 PRO A CD  1 
ATOM   7470 N  N   . VAL B 1 531 ? 112.749 147.743 133.473 1.00 57.57  ? 531 VAL A N   1 
ATOM   7471 C  CA  . VAL B 1 531 ? 112.419 146.659 132.557 1.00 57.57  ? 531 VAL A CA  1 
ATOM   7472 C  C   . VAL B 1 531 ? 113.207 146.730 131.259 1.00 57.57  ? 531 VAL A C   1 
ATOM   7473 O  O   . VAL B 1 531 ? 113.218 145.756 130.497 1.00 57.57  ? 531 VAL A O   1 
ATOM   7474 C  CB  . VAL B 1 531 ? 110.903 146.666 132.267 1.00 57.57  ? 531 VAL A CB  1 
ATOM   7475 C  CG1 . VAL B 1 531 ? 110.548 147.783 131.299 1.00 57.57  ? 531 VAL A CG1 1 
ATOM   7476 C  CG2 . VAL B 1 531 ? 110.437 145.311 131.749 1.00 57.57  ? 531 VAL A CG2 1 
ATOM   7477 N  N   . ALA B 1 532 ? 113.877 147.854 130.992 1.00 57.87  ? 532 ALA A N   1 
ATOM   7478 C  CA  . ALA B 1 532 ? 114.562 148.027 129.714 1.00 57.87  ? 532 ALA A CA  1 
ATOM   7479 C  C   . ALA B 1 532 ? 115.687 147.014 129.541 1.00 57.87  ? 532 ALA A C   1 
ATOM   7480 O  O   . ALA B 1 532 ? 115.769 146.333 128.513 1.00 57.87  ? 532 ALA A O   1 
ATOM   7481 C  CB  . ALA B 1 532 ? 115.100 149.452 129.599 1.00 57.87  ? 532 ALA A CB  1 
ATOM   7482 N  N   . ASN B 1 533 ? 116.561 146.897 130.534 1.00 59.12  ? 533 ASN A N   1 
ATOM   7483 C  CA  . ASN B 1 533 ? 117.713 146.013 130.434 1.00 59.12  ? 533 ASN A CA  1 
ATOM   7484 C  C   . ASN B 1 533 ? 118.113 145.569 131.833 1.00 59.12  ? 533 ASN A C   1 
ATOM   7485 O  O   . ASN B 1 533 ? 117.800 146.249 132.817 1.00 59.12  ? 533 ASN A O   1 
ATOM   7486 C  CB  . ASN B 1 533 ? 118.881 146.702 129.715 1.00 59.12  ? 533 ASN A CB  1 
ATOM   7487 C  CG  . ASN B 1 533 ? 119.233 148.038 130.321 1.00 59.12  ? 533 ASN A CG  1 
ATOM   7488 O  OD1 . ASN B 1 533 ? 118.575 148.505 131.248 1.00 59.12  ? 533 ASN A OD1 1 
ATOM   7489 N  ND2 . ASN B 1 533 ? 120.275 148.668 129.795 1.00 59.12  ? 533 ASN A ND2 1 
ATOM   7490 N  N   . PRO B 1 534 ? 118.787 144.427 131.955 1.00 57.87  ? 534 PRO A N   1 
ATOM   7491 C  CA  . PRO B 1 534 ? 119.084 143.857 133.280 1.00 57.87  ? 534 PRO A CA  1 
ATOM   7492 C  C   . PRO B 1 534 ? 119.884 144.785 134.183 1.00 57.87  ? 534 PRO A C   1 
ATOM   7493 O  O   . PRO B 1 534 ? 119.637 144.795 135.398 1.00 57.87  ? 534 PRO A O   1 
ATOM   7494 C  CB  . PRO B 1 534 ? 119.878 142.587 132.943 1.00 57.87  ? 534 PRO A CB  1 
ATOM   7495 C  CG  . PRO B 1 534 ? 119.373 142.189 131.608 1.00 57.87  ? 534 PRO A CG  1 
ATOM   7496 C  CD  . PRO B 1 534 ? 119.072 143.467 130.872 1.00 57.87  ? 534 PRO A CD  1 
ATOM   7497 N  N   . PRO B 1 535 ? 120.874 145.541 133.675 1.00 55.68  ? 535 PRO A N   1 
ATOM   7498 C  CA  . PRO B 1 535 ? 121.611 146.429 134.598 1.00 55.68  ? 535 PRO A CA  1 
ATOM   7499 C  C   . PRO B 1 535 ? 120.724 147.426 135.323 1.00 55.68  ? 535 PRO A C   1 
ATOM   7500 O  O   . PRO B 1 535 ? 120.902 147.652 136.530 1.00 55.68  ? 535 PRO A O   1 
ATOM   7501 C  CB  . PRO B 1 535 ? 122.616 147.130 133.676 1.00 55.68  ? 535 PRO A CB  1 
ATOM   7502 C  CG  . PRO B 1 535 ? 122.853 146.161 132.601 1.00 55.68  ? 535 PRO A CG  1 
ATOM   7503 C  CD  . PRO B 1 535 ? 121.523 145.520 132.349 1.00 55.68  ? 535 PRO A CD  1 
ATOM   7504 N  N   . ASN B 1 536 ? 119.755 148.017 134.621 1.00 56.03  ? 536 ASN A N   1 
ATOM   7505 C  CA  . ASN B 1 536 ? 118.847 148.958 135.265 1.00 56.03  ? 536 ASN A CA  1 
ATOM   7506 C  C   . ASN B 1 536 ? 117.997 148.264 136.318 1.00 56.03  ? 536 ASN A C   1 
ATOM   7507 O  O   . ASN B 1 536 ? 117.761 148.816 137.399 1.00 56.03  ? 536 ASN A O   1 
ATOM   7508 C  CB  . ASN B 1 536 ? 117.965 149.633 134.218 1.00 56.03  ? 536 ASN A CB  1 
ATOM   7509 C  CG  . ASN B 1 536 ? 118.728 150.624 133.367 1.00 56.03  ? 536 ASN A CG  1 
ATOM   7510 O  OD1 . ASN B 1 536 ? 119.760 151.146 133.780 1.00 56.03  ? 536 ASN A OD1 1 
ATOM   7511 N  ND2 . ASN B 1 536 ? 118.223 150.887 132.170 1.00 56.03  ? 536 ASN A ND2 1 
ATOM   7512 N  N   . ALA B 1 537 ? 117.527 147.051 136.020 1.00 57.05  ? 537 ALA A N   1 
ATOM   7513 C  CA  . ALA B 1 537 ? 116.742 146.302 136.994 1.00 57.05  ? 537 ALA A CA  1 
ATOM   7514 C  C   . ALA B 1 537 ? 117.561 145.991 138.238 1.00 57.05  ? 537 ALA A C   1 
ATOM   7515 O  O   . ALA B 1 537 ? 117.068 146.120 139.362 1.00 57.05  ? 537 ALA A O   1 
ATOM   7516 C  CB  . ALA B 1 537 ? 116.212 145.014 136.366 1.00 57.05  ? 537 ALA A CB  1 
ATOM   7517 N  N   . ILE B 1 538 ? 118.819 145.585 138.056 1.00 58.26  ? 538 ILE A N   1 
ATOM   7518 C  CA  . ILE B 1 538 ? 119.676 145.276 139.198 1.00 58.26  ? 538 ILE A CA  1 
ATOM   7519 C  C   . ILE B 1 538 ? 119.907 146.519 140.043 1.00 58.26  ? 538 ILE A C   1 
ATOM   7520 O  O   . ILE B 1 538 ? 119.843 146.470 141.278 1.00 58.26  ? 538 ILE A O   1 
ATOM   7521 C  CB  . ILE B 1 538 ? 121.005 144.666 138.721 1.00 58.26  ? 538 ILE A CB  1 
ATOM   7522 C  CG1 . ILE B 1 538 ? 120.762 143.309 138.067 1.00 58.26  ? 538 ILE A CG1 1 
ATOM   7523 C  CG2 . ILE B 1 538 ? 121.980 144.534 139.877 1.00 58.26  ? 538 ILE A CG2 1 
ATOM   7524 C  CD1 . ILE B 1 538 ? 121.847 142.909 137.114 1.00 58.26  ? 538 ILE A CD1 1 
ATOM   7525 N  N   . VAL B 1 539 ? 120.177 147.652 139.396 1.00 60.27  ? 539 VAL A N   1 
ATOM   7526 C  CA  . VAL B 1 539 ? 120.423 148.882 140.141 1.00 60.27  ? 539 VAL A CA  1 
ATOM   7527 C  C   . VAL B 1 539 ? 119.171 149.314 140.896 1.00 60.27  ? 539 VAL A C   1 
ATOM   7528 O  O   . VAL B 1 539 ? 119.243 149.725 142.061 1.00 60.27  ? 539 VAL A O   1 
ATOM   7529 C  CB  . VAL B 1 539 ? 120.933 149.978 139.191 1.00 60.27  ? 539 VAL A CB  1 
ATOM   7530 C  CG1 . VAL B 1 539 ? 120.787 151.347 139.825 1.00 60.27  ? 539 VAL A CG1 1 
ATOM   7531 C  CG2 . VAL B 1 539 ? 122.376 149.701 138.830 1.00 60.27  ? 539 VAL A CG2 1 
ATOM   7532 N  N   . PHE B 1 540 ? 118.004 149.221 140.255 1.00 63.30  ? 540 PHE A N   1 
ATOM   7533 C  CA  . PHE B 1 540 ? 116.755 149.592 140.909 1.00 63.30  ? 540 PHE A CA  1 
ATOM   7534 C  C   . PHE B 1 540 ? 116.345 148.599 141.989 1.00 63.30  ? 540 PHE A C   1 
ATOM   7535 O  O   . PHE B 1 540 ? 115.552 148.953 142.867 1.00 63.30  ? 540 PHE A O   1 
ATOM   7536 C  CB  . PHE B 1 540 ? 115.644 149.717 139.866 1.00 63.30  ? 540 PHE A CB  1 
ATOM   7537 C  CG  . PHE B 1 540 ? 114.430 150.448 140.355 1.00 63.30  ? 540 PHE A CG  1 
ATOM   7538 C  CD1 . PHE B 1 540 ? 114.413 151.830 140.404 1.00 63.30  ? 540 PHE A CD1 1 
ATOM   7539 C  CD2 . PHE B 1 540 ? 113.302 149.755 140.758 1.00 63.30  ? 540 PHE A CD2 1 
ATOM   7540 C  CE1 . PHE B 1 540 ? 113.298 152.507 140.849 1.00 63.30  ? 540 PHE A CE1 1 
ATOM   7541 C  CE2 . PHE B 1 540 ? 112.182 150.427 141.205 1.00 63.30  ? 540 PHE A CE2 1 
ATOM   7542 C  CZ  . PHE B 1 540 ? 112.181 151.806 141.251 1.00 63.30  ? 540 PHE A CZ  1 
ATOM   7543 N  N   . SER B 1 541 ? 116.864 147.368 141.943 1.00 65.06  ? 541 SER A N   1 
ATOM   7544 C  CA  . SER B 1 541 ? 116.490 146.369 142.938 1.00 65.06  ? 541 SER A CA  1 
ATOM   7545 C  C   . SER B 1 541 ? 116.920 146.774 144.341 1.00 65.06  ? 541 SER A C   1 
ATOM   7546 O  O   . SER B 1 541 ? 116.350 146.291 145.326 1.00 65.06  ? 541 SER A O   1 
ATOM   7547 C  CB  . SER B 1 541 ? 117.090 145.012 142.569 1.00 65.06  ? 541 SER A CB  1 
ATOM   7548 O  OG  . SER B 1 541 ? 118.433 144.909 143.007 1.00 65.06  ? 541 SER A OG  1 
ATOM   7549 N  N   . TYR B 1 542 ? 117.917 147.651 144.460 1.00 69.10  ? 542 TYR A N   1 
ATOM   7550 C  CA  . TYR B 1 542 ? 118.307 148.132 145.779 1.00 69.10  ? 542 TYR A CA  1 
ATOM   7551 C  C   . TYR B 1 542 ? 117.277 149.075 146.381 1.00 69.10  ? 542 TYR A C   1 
ATOM   7552 O  O   . TYR B 1 542 ? 117.326 149.328 147.588 1.00 69.10  ? 542 TYR A O   1 
ATOM   7553 C  CB  . TYR B 1 542 ? 119.674 148.816 145.706 1.00 69.10  ? 542 TYR A CB  1 
ATOM   7554 C  CG  . TYR B 1 542 ? 120.825 147.835 145.708 1.00 69.10  ? 542 TYR A CG  1 
ATOM   7555 C  CD1 . TYR B 1 542 ? 121.004 146.947 144.657 1.00 69.10  ? 542 TYR A CD1 1 
ATOM   7556 C  CD2 . TYR B 1 542 ? 121.726 147.791 146.762 1.00 69.10  ? 542 TYR A CD2 1 
ATOM   7557 C  CE1 . TYR B 1 542 ? 122.046 146.044 144.654 1.00 69.10  ? 542 TYR A CE1 1 
ATOM   7558 C  CE2 . TYR B 1 542 ? 122.773 146.892 146.767 1.00 69.10  ? 542 TYR A CE2 1 
ATOM   7559 C  CZ  . TYR B 1 542 ? 122.929 146.021 145.710 1.00 69.10  ? 542 TYR A CZ  1 
ATOM   7560 O  OH  . TYR B 1 542 ? 123.971 145.125 145.712 1.00 69.10  ? 542 TYR A OH  1 
ATOM   7561 N  N   . GLY B 1 543 ? 116.337 149.573 145.584 1.00 73.02  ? 543 GLY A N   1 
ATOM   7562 C  CA  . GLY B 1 543 ? 115.252 150.378 146.111 1.00 73.02  ? 543 GLY A CA  1 
ATOM   7563 C  C   . GLY B 1 543 ? 115.662 151.709 146.693 1.00 73.02  ? 543 GLY A C   1 
ATOM   7564 O  O   . GLY B 1 543 ? 115.066 152.155 147.678 1.00 73.02  ? 543 GLY A O   1 
ATOM   7565 N  N   . HIS B 1 544 ? 116.670 152.360 146.115 1.00 76.62  ? 544 HIS A N   1 
ATOM   7566 C  CA  . HIS B 1 544 ? 117.031 153.722 146.484 1.00 76.62  ? 544 HIS A CA  1 
ATOM   7567 C  C   . HIS B 1 544 ? 116.830 154.706 145.339 1.00 76.62  ? 544 HIS A C   1 
ATOM   7568 O  O   . HIS B 1 544 ? 117.359 155.820 145.394 1.00 76.62  ? 544 HIS A O   1 
ATOM   7569 C  CB  . HIS B 1 544 ? 118.477 153.793 146.988 1.00 76.62  ? 544 HIS A CB  1 
ATOM   7570 C  CG  . HIS B 1 544 ? 118.760 152.909 148.165 1.00 76.62  ? 544 HIS A CG  1 
ATOM   7571 N  ND1 . HIS B 1 544 ? 118.547 151.547 148.151 1.00 76.62  ? 544 HIS A ND1 1 
ATOM   7572 C  CD2 . HIS B 1 544 ? 119.216 153.204 149.405 1.00 76.62  ? 544 HIS A CD2 1 
ATOM   7573 C  CE1 . HIS B 1 544 ? 118.881 151.039 149.325 1.00 76.62  ? 544 HIS A CE1 1 
ATOM   7574 N  NE2 . HIS B 1 544 ? 119.287 152.024 150.105 1.00 76.62  ? 544 HIS A NE2 1 
ATOM   7575 N  N   . LEU B 1 545 ? 116.080 154.325 144.308 1.00 69.57  ? 545 LEU A N   1 
ATOM   7576 C  CA  . LEU B 1 545 ? 115.799 155.192 143.175 1.00 69.57  ? 545 LEU A CA  1 
ATOM   7577 C  C   . LEU B 1 545 ? 114.298 155.270 142.946 1.00 69.57  ? 545 LEU A C   1 
ATOM   7578 O  O   . LEU B 1 545 ? 113.547 154.367 143.321 1.00 69.57  ? 545 LEU A O   1 
ATOM   7579 C  CB  . LEU B 1 545 ? 116.482 154.695 141.894 1.00 69.57  ? 545 LEU A CB  1 
ATOM   7580 C  CG  . LEU B 1 545 ? 117.859 155.273 141.570 1.00 69.57  ? 545 LEU A CG  1 
ATOM   7581 C  CD1 . LEU B 1 545 ? 118.387 154.677 140.280 1.00 69.57  ? 545 LEU A CD1 1 
ATOM   7582 C  CD2 . LEU B 1 545 ? 117.793 156.786 141.475 1.00 69.57  ? 545 LEU A CD2 1 
ATOM   7583 N  N   . LYS B 1 546 ? 113.868 156.364 142.326 1.00 68.28  ? 546 LYS A N   1 
ATOM   7584 C  CA  . LYS B 1 546 ? 112.486 156.544 141.914 1.00 68.28  ? 546 LYS A CA  1 
ATOM   7585 C  C   . LYS B 1 546 ? 112.409 156.599 140.395 1.00 68.28  ? 546 LYS A C   1 
ATOM   7586 O  O   . LYS B 1 546 ? 113.342 157.052 139.725 1.00 68.28  ? 546 LYS A O   1 
ATOM   7587 C  CB  . LYS B 1 546 ? 111.883 157.816 142.517 1.00 68.28  ? 546 LYS A CB  1 
ATOM   7588 C  CG  . LYS B 1 546 ? 111.652 157.738 144.016 1.00 68.28  ? 546 LYS A CG  1 
ATOM   7589 C  CD  . LYS B 1 546 ? 111.112 159.049 144.562 1.00 68.28  ? 546 LYS A CD  1 
ATOM   7590 C  CE  . LYS B 1 546 ? 112.072 160.195 144.293 1.00 68.28  ? 546 LYS A CE  1 
ATOM   7591 N  NZ  . LYS B 1 546 ? 111.590 161.474 144.883 1.00 68.28  ? 546 LYS A NZ  1 
ATOM   7592 N  N   . VAL B 1 547 ? 111.283 156.127 139.857 1.00 64.34  ? 547 VAL A N   1 
ATOM   7593 C  CA  . VAL B 1 547 ? 111.124 156.043 138.409 1.00 64.34  ? 547 VAL A CA  1 
ATOM   7594 C  C   . VAL B 1 547 ? 111.210 157.422 137.770 1.00 64.34  ? 547 VAL A C   1 
ATOM   7595 O  O   . VAL B 1 547 ? 111.760 157.572 136.672 1.00 64.34  ? 547 VAL A O   1 
ATOM   7596 C  CB  . VAL B 1 547 ? 109.798 155.339 138.063 1.00 64.34  ? 547 VAL A CB  1 
ATOM   7597 C  CG1 . VAL B 1 547 ? 109.617 155.243 136.556 1.00 64.34  ? 547 VAL A CG1 1 
ATOM   7598 C  CG2 . VAL B 1 547 ? 109.755 153.961 138.698 1.00 64.34  ? 547 VAL A CG2 1 
ATOM   7599 N  N   . ILE B 1 548 ? 110.675 158.447 138.437 1.00 63.82  ? 548 ILE A N   1 
ATOM   7600 C  CA  . ILE B 1 548 ? 110.681 159.792 137.866 1.00 63.82  ? 548 ILE A CA  1 
ATOM   7601 C  C   . ILE B 1 548 ? 112.110 160.291 137.684 1.00 63.82  ? 548 ILE A C   1 
ATOM   7602 O  O   . ILE B 1 548 ? 112.471 160.818 136.626 1.00 63.82  ? 548 ILE A O   1 
ATOM   7603 C  CB  . ILE B 1 548 ? 109.858 160.751 138.744 1.00 63.82  ? 548 ILE A CB  1 
ATOM   7604 C  CG1 . ILE B 1 548 ? 108.515 160.117 139.112 1.00 63.82  ? 548 ILE A CG1 1 
ATOM   7605 C  CG2 . ILE B 1 548 ? 109.652 162.076 138.030 1.00 63.82  ? 548 ILE A CG2 1 
ATOM   7606 C  CD1 . ILE B 1 548 ? 107.648 159.781 137.919 1.00 63.82  ? 548 ILE A CD1 1 
ATOM   7607 N  N   . ASP B 1 549 ? 112.944 160.133 138.715 1.00 66.30  ? 549 ASP A N   1 
ATOM   7608 C  CA  . ASP B 1 549 ? 114.332 160.577 138.619 1.00 66.30  ? 549 ASP A CA  1 
ATOM   7609 C  C   . ASP B 1 549 ? 115.094 159.783 137.567 1.00 66.30  ? 549 ASP A C   1 
ATOM   7610 O  O   . ASP B 1 549 ? 115.901 160.344 136.811 1.00 66.30  ? 549 ASP A O   1 
ATOM   7611 C  CB  . ASP B 1 549 ? 115.019 160.457 139.979 1.00 66.30  ? 549 ASP A CB  1 
ATOM   7612 C  CG  . ASP B 1 549 ? 114.576 161.531 140.952 1.00 66.30  ? 549 ASP A CG  1 
ATOM   7613 O  OD1 . ASP B 1 549 ? 114.341 162.675 140.510 1.00 66.30  ? 549 ASP A OD1 1 
ATOM   7614 O  OD2 . ASP B 1 549 ? 114.462 161.231 142.159 1.00 66.30  ? 549 ASP A OD2 1 
ATOM   7615 N  N   . MET B 1 550 ? 114.858 158.472 137.511 1.00 58.95  ? 550 MET A N   1 
ATOM   7616 C  CA  . MET B 1 550 ? 115.532 157.643 136.520 1.00 58.95  ? 550 MET A CA  1 
ATOM   7617 C  C   . MET B 1 550 ? 115.170 158.079 135.109 1.00 58.95  ? 550 MET A C   1 
ATOM   7618 O  O   . MET B 1 550 ? 116.043 158.186 134.243 1.00 58.95  ? 550 MET A O   1 
ATOM   7619 C  CB  . MET B 1 550 ? 115.175 156.175 136.741 1.00 58.95  ? 550 MET A CB  1 
ATOM   7620 C  CG  . MET B 1 550 ? 115.852 155.223 135.783 1.00 58.95  ? 550 MET A CG  1 
ATOM   7621 S  SD  . MET B 1 550 ? 116.246 153.663 136.589 1.00 58.95  ? 550 MET A SD  1 
ATOM   7622 C  CE  . MET B 1 550 ? 117.458 153.005 135.455 1.00 58.95  ? 550 MET A CE  1 
ATOM   7623 N  N   . VAL B 1 551 ? 113.887 158.354 134.865 1.00 58.13  ? 551 VAL A N   1 
ATOM   7624 C  CA  . VAL B 1 551 ? 113.456 158.814 133.549 1.00 58.13  ? 551 VAL A CA  1 
ATOM   7625 C  C   . VAL B 1 551 ? 114.051 160.183 133.236 1.00 58.13  ? 551 VAL A C   1 
ATOM   7626 O  O   . VAL B 1 551 ? 114.486 160.441 132.107 1.00 58.13  ? 551 VAL A O   1 
ATOM   7627 C  CB  . VAL B 1 551 ? 111.919 158.827 133.470 1.00 58.13  ? 551 VAL A CB  1 
ATOM   7628 C  CG1 . VAL B 1 551 ? 111.450 159.610 132.257 1.00 58.13  ? 551 VAL A CG1 1 
ATOM   7629 C  CG2 . VAL B 1 551 ? 111.382 157.408 133.427 1.00 58.13  ? 551 VAL A CG2 1 
ATOM   7630 N  N   . LYS B 1 552 ? 114.082 161.079 134.226 1.00 57.90  ? 552 LYS A N   1 
ATOM   7631 C  CA  . LYS B 1 552 ? 114.630 162.413 133.996 1.00 57.90  ? 552 LYS A CA  1 
ATOM   7632 C  C   . LYS B 1 552 ? 116.099 162.350 133.603 1.00 57.90  ? 552 LYS A C   1 
ATOM   7633 O  O   . LYS B 1 552 ? 116.534 163.058 132.688 1.00 57.90  ? 552 LYS A O   1 
ATOM   7634 C  CB  . LYS B 1 552 ? 114.450 163.278 135.242 1.00 57.90  ? 552 LYS A CB  1 
ATOM   7635 C  CG  . LYS B 1 552 ? 113.039 163.796 135.445 1.00 57.90  ? 552 LYS A CG  1 
ATOM   7636 C  CD  . LYS B 1 552 ? 112.997 164.852 136.535 1.00 57.90  ? 552 LYS A CD  1 
ATOM   7637 C  CE  . LYS B 1 552 ? 113.743 164.388 137.776 1.00 57.90  ? 552 LYS A CE  1 
ATOM   7638 N  NZ  . LYS B 1 552 ? 113.828 165.455 138.811 1.00 57.90  ? 552 LYS A NZ  1 
ATOM   7639 N  N   . ALA B 1 553 ? 116.883 161.514 134.285 1.00 54.46  ? 553 ALA A N   1 
ATOM   7640 C  CA  . ALA B 1 553 ? 118.293 161.385 133.926 1.00 54.46  ? 553 ALA A CA  1 
ATOM   7641 C  C   . ALA B 1 553 ? 118.460 160.672 132.589 1.00 54.46  ? 553 ALA A C   1 
ATOM   7642 O  O   . ALA B 1 553 ? 119.299 161.063 131.762 1.00 54.46  ? 553 ALA A O   1 
ATOM   7643 C  CB  . ALA B 1 553 ? 119.050 160.647 135.027 1.00 54.46  ? 553 ALA A CB  1 
ATOM   7644 N  N   . GLY B 1 554 ? 117.662 159.630 132.353 1.00 50.84  ? 554 GLY A N   1 
ATOM   7645 C  CA  . GLY B 1 554 ? 117.828 158.839 131.153 1.00 50.84  ? 554 GLY A CA  1 
ATOM   7646 C  C   . GLY B 1 554 ? 117.417 159.557 129.889 1.00 50.84  ? 554 GLY A C   1 
ATOM   7647 O  O   . GLY B 1 554 ? 117.948 159.266 128.819 1.00 50.84  ? 554 GLY A O   1 
ATOM   7648 N  N   . LEU B 1 555 ? 116.475 160.496 129.983 1.00 50.63  ? 555 LEU A N   1 
ATOM   7649 C  CA  . LEU B 1 555 ? 116.129 161.289 128.809 1.00 50.63  ? 555 LEU A CA  1 
ATOM   7650 C  C   . LEU B 1 555 ? 117.338 162.073 128.315 1.00 50.63  ? 555 LEU A C   1 
ATOM   7651 O  O   . LEU B 1 555 ? 117.670 162.046 127.123 1.00 50.63  ? 555 LEU A O   1 
ATOM   7652 C  CB  . LEU B 1 555 ? 114.968 162.227 129.129 1.00 50.63  ? 555 LEU A CB  1 
ATOM   7653 C  CG  . LEU B 1 555 ? 113.574 161.630 128.948 1.00 50.63  ? 555 LEU A CG  1 
ATOM   7654 C  CD1 . LEU B 1 555 ? 112.517 162.544 129.542 1.00 50.63  ? 555 LEU A CD1 1 
ATOM   7655 C  CD2 . LEU B 1 555 ? 113.299 161.371 127.478 1.00 50.63  ? 555 LEU A CD2 1 
ATOM   7656 N  N   . GLY B 1 556 ? 118.028 162.756 129.230 1.00 49.34  ? 556 GLY A N   1 
ATOM   7657 C  CA  . GLY B 1 556 ? 119.225 163.482 128.846 1.00 49.34  ? 556 GLY A CA  1 
ATOM   7658 C  C   . GLY B 1 556 ? 120.334 162.567 128.368 1.00 49.34  ? 556 GLY A C   1 
ATOM   7659 O  O   . GLY B 1 556 ? 121.016 162.866 127.383 1.00 49.34  ? 556 GLY A O   1 
ATOM   7660 N  N   . VAL B 1 557 ? 120.527 161.435 129.051 1.00 48.20  ? 557 VAL A N   1 
ATOM   7661 C  CA  . VAL B 1 557 ? 121.582 160.510 128.641 1.00 48.20  ? 557 VAL A CA  1 
ATOM   7662 C  C   . VAL B 1 557 ? 121.309 159.966 127.244 1.00 48.20  ? 557 VAL A C   1 
ATOM   7663 O  O   . VAL B 1 557 ? 122.214 159.883 126.407 1.00 48.20  ? 557 VAL A O   1 
ATOM   7664 C  CB  . VAL B 1 557 ? 121.737 159.379 129.671 1.00 48.20  ? 557 VAL A CB  1 
ATOM   7665 C  CG1 . VAL B 1 557 ? 122.636 158.287 129.120 1.00 48.20  ? 557 VAL A CG1 1 
ATOM   7666 C  CG2 . VAL B 1 557 ? 122.308 159.930 130.962 1.00 48.20  ? 557 VAL A CG2 1 
ATOM   7667 N  N   . ASN B 1 558 ? 120.057 159.592 126.968 1.00 47.69  ? 558 ASN A N   1 
ATOM   7668 C  CA  . ASN B 1 558 ? 119.698 159.059 125.660 1.00 47.69  ? 558 ASN A CA  1 
ATOM   7669 C  C   . ASN B 1 558 ? 119.816 160.121 124.575 1.00 47.69  ? 558 ASN A C   1 
ATOM   7670 O  O   . ASN B 1 558 ? 120.255 159.824 123.459 1.00 47.69  ? 558 ASN A O   1 
ATOM   7671 C  CB  . ASN B 1 558 ? 118.282 158.490 125.705 1.00 47.69  ? 558 ASN A CB  1 
ATOM   7672 C  CG  . ASN B 1 558 ? 118.067 157.393 124.692 1.00 47.69  ? 558 ASN A CG  1 
ATOM   7673 O  OD1 . ASN B 1 558 ? 118.318 157.576 123.503 1.00 47.69  ? 558 ASN A OD1 1 
ATOM   7674 N  ND2 . ASN B 1 558 ? 117.597 156.243 125.155 1.00 47.69  ? 558 ASN A ND2 1 
ATOM   7675 N  N   . ILE B 1 559 ? 119.423 161.362 124.877 1.00 46.80  ? 559 ILE A N   1 
ATOM   7676 C  CA  . ILE B 1 559 ? 119.577 162.437 123.902 1.00 46.80  ? 559 ILE A CA  1 
ATOM   7677 C  C   . ILE B 1 559 ? 121.048 162.642 123.568 1.00 46.80  ? 559 ILE A C   1 
ATOM   7678 O  O   . ILE B 1 559 ? 121.424 162.765 122.395 1.00 46.80  ? 559 ILE A O   1 
ATOM   7679 C  CB  . ILE B 1 559 ? 118.927 163.731 124.423 1.00 46.80  ? 559 ILE A CB  1 
ATOM   7680 C  CG1 . ILE B 1 559 ? 117.405 163.647 124.305 1.00 46.80  ? 559 ILE A CG1 1 
ATOM   7681 C  CG2 . ILE B 1 559 ? 119.454 164.938 123.666 1.00 46.80  ? 559 ILE A CG2 1 
ATOM   7682 C  CD1 . ILE B 1 559 ? 116.679 164.810 124.939 1.00 46.80  ? 559 ILE A CD1 1 
ATOM   7683 N  N   . VAL B 1 560 ? 121.905 162.664 124.592 1.00 47.32  ? 560 VAL A N   1 
ATOM   7684 C  CA  . VAL B 1 560 ? 123.335 162.839 124.359 1.00 47.32  ? 560 VAL A CA  1 
ATOM   7685 C  C   . VAL B 1 560 ? 123.890 161.681 123.540 1.00 47.32  ? 560 VAL A C   1 
ATOM   7686 O  O   . VAL B 1 560 ? 124.675 161.882 122.605 1.00 47.32  ? 560 VAL A O   1 
ATOM   7687 C  CB  . VAL B 1 560 ? 124.078 162.995 125.699 1.00 47.32  ? 560 VAL A CB  1 
ATOM   7688 C  CG1 . VAL B 1 560 ? 125.558 162.718 125.521 1.00 47.32  ? 560 VAL A CG1 1 
ATOM   7689 C  CG2 . VAL B 1 560 ? 123.859 164.388 126.265 1.00 47.32  ? 560 VAL A CG2 1 
ATOM   7690 N  N   . GLY B 1 561 ? 123.489 160.453 123.873 1.00 47.41  ? 561 GLY A N   1 
ATOM   7691 C  CA  . GLY B 1 561 ? 123.981 159.301 123.136 1.00 47.41  ? 561 GLY A CA  1 
ATOM   7692 C  C   . GLY B 1 561 ? 123.566 159.317 121.677 1.00 47.41  ? 561 GLY A C   1 
ATOM   7693 O  O   . GLY B 1 561 ? 124.377 159.041 120.790 1.00 47.41  ? 561 GLY A O   1 
ATOM   7694 N  N   . VAL B 1 562 ? 122.300 159.643 121.409 1.00 47.11  ? 562 VAL A N   1 
ATOM   7695 C  CA  . VAL B 1 562 ? 121.824 159.707 120.031 1.00 47.11  ? 562 VAL A CA  1 
ATOM   7696 C  C   . VAL B 1 562 ? 122.555 160.802 119.265 1.00 47.11  ? 562 VAL A C   1 
ATOM   7697 O  O   . VAL B 1 562 ? 122.962 160.608 118.112 1.00 47.11  ? 562 VAL A O   1 
ATOM   7698 C  CB  . VAL B 1 562 ? 120.298 159.911 120.004 1.00 47.11  ? 562 VAL A CB  1 
ATOM   7699 C  CG1 . VAL B 1 562 ? 119.837 160.316 118.617 1.00 47.11  ? 562 VAL A CG1 1 
ATOM   7700 C  CG2 . VAL B 1 562 ? 119.592 158.644 120.449 1.00 47.11  ? 562 VAL A CG2 1 
ATOM   7701 N  N   . ALA B 1 563 ? 122.740 161.967 119.893 1.00 48.52  ? 563 ALA A N   1 
ATOM   7702 C  CA  . ALA B 1 563 ? 123.452 163.052 119.227 1.00 48.52  ? 563 ALA A CA  1 
ATOM   7703 C  C   . ALA B 1 563 ? 124.884 162.654 118.897 1.00 48.52  ? 563 ALA A C   1 
ATOM   7704 O  O   . ALA B 1 563 ? 125.372 162.927 117.794 1.00 48.52  ? 563 ALA A O   1 
ATOM   7705 C  CB  . ALA B 1 563 ? 123.432 164.306 120.100 1.00 48.52  ? 563 ALA A CB  1 
ATOM   7706 N  N   . VAL B 1 564 ? 125.571 161.999 119.834 1.00 49.39  ? 564 VAL A N   1 
ATOM   7707 C  CA  . VAL B 1 564 ? 126.956 161.606 119.593 1.00 49.39  ? 564 VAL A CA  1 
ATOM   7708 C  C   . VAL B 1 564 ? 127.032 160.535 118.513 1.00 49.39  ? 564 VAL A C   1 
ATOM   7709 O  O   . VAL B 1 564 ? 127.948 160.539 117.684 1.00 49.39  ? 564 VAL A O   1 
ATOM   7710 C  CB  . VAL B 1 564 ? 127.618 161.145 120.903 1.00 49.39  ? 564 VAL A CB  1 
ATOM   7711 C  CG1 . VAL B 1 564 ? 128.972 160.517 120.624 1.00 49.39  ? 564 VAL A CG1 1 
ATOM   7712 C  CG2 . VAL B 1 564 ? 127.766 162.318 121.854 1.00 49.39  ? 564 VAL A CG2 1 
ATOM   7713 N  N   . VAL B 1 565 ? 126.076 159.604 118.495 1.00 50.58  ? 565 VAL A N   1 
ATOM   7714 C  CA  . VAL B 1 565 ? 126.072 158.574 117.459 1.00 50.58  ? 565 VAL A CA  1 
ATOM   7715 C  C   . VAL B 1 565 ? 125.863 159.200 116.086 1.00 50.58  ? 565 VAL A C   1 
ATOM   7716 O  O   . VAL B 1 565 ? 126.530 158.831 115.111 1.00 50.58  ? 565 VAL A O   1 
ATOM   7717 C  CB  . VAL B 1 565 ? 125.008 157.505 117.766 1.00 50.58  ? 565 VAL A CB  1 
ATOM   7718 C  CG1 . VAL B 1 565 ? 124.748 156.645 116.541 1.00 50.58  ? 565 VAL A CG1 1 
ATOM   7719 C  CG2 . VAL B 1 565 ? 125.454 156.641 118.930 1.00 50.58  ? 565 VAL A CG2 1 
ATOM   7720 N  N   . MET B 1 566 ? 124.935 160.156 115.984 1.00 56.39  ? 566 MET A N   1 
ATOM   7721 C  CA  . MET B 1 566 ? 124.718 160.828 114.707 1.00 56.39  ? 566 MET A CA  1 
ATOM   7722 C  C   . MET B 1 566 ? 125.949 161.622 114.286 1.00 56.39  ? 566 MET A C   1 
ATOM   7723 O  O   . MET B 1 566 ? 126.319 161.628 113.104 1.00 56.39  ? 566 MET A O   1 
ATOM   7724 C  CB  . MET B 1 566 ? 123.495 161.739 114.792 1.00 56.39  ? 566 MET A CB  1 
ATOM   7725 C  CG  . MET B 1 566 ? 122.195 160.993 115.010 1.00 56.39  ? 566 MET A CG  1 
ATOM   7726 S  SD  . MET B 1 566 ? 121.781 159.904 113.639 1.00 56.39  ? 566 MET A SD  1 
ATOM   7727 C  CE  . MET B 1 566 ? 120.373 159.039 114.323 1.00 56.39  ? 566 MET A CE  1 
ATOM   7728 N  N   . LEU B 1 567 ? 126.596 162.294 115.240 1.00 53.91  ? 567 LEU A N   1 
ATOM   7729 C  CA  . LEU B 1 567 ? 127.815 163.032 114.933 1.00 53.91  ? 567 LEU A CA  1 
ATOM   7730 C  C   . LEU B 1 567 ? 128.908 162.099 114.431 1.00 53.91  ? 567 LEU A C   1 
ATOM   7731 O  O   . LEU B 1 567 ? 129.634 162.431 113.489 1.00 53.91  ? 567 LEU A O   1 
ATOM   7732 C  CB  . LEU B 1 567 ? 128.284 163.796 116.171 1.00 53.91  ? 567 LEU A CB  1 
ATOM   7733 C  CG  . LEU B 1 567 ? 129.319 164.907 115.992 1.00 53.91  ? 567 LEU A CG  1 
ATOM   7734 C  CD1 . LEU B 1 567 ? 129.030 166.044 116.955 1.00 53.91  ? 567 LEU A CD1 1 
ATOM   7735 C  CD2 . LEU B 1 567 ? 130.727 164.376 116.205 1.00 53.91  ? 567 LEU A CD2 1 
ATOM   7736 N  N   . GLY B 1 568 ? 129.040 160.926 115.052 1.00 58.67  ? 568 GLY A N   1 
ATOM   7737 C  CA  . GLY B 1 568 ? 130.031 159.965 114.598 1.00 58.67  ? 568 GLY A CA  1 
ATOM   7738 C  C   . GLY B 1 568 ? 129.724 159.418 113.218 1.00 58.67  ? 568 GLY A C   1 
ATOM   7739 O  O   . GLY B 1 568 ? 130.627 159.244 112.395 1.00 58.67  ? 568 GLY A O   1 
ATOM   7740 N  N   . ILE B 1 569 ? 128.449 159.135 112.946 1.00 59.10  ? 569 ILE A N   1 
ATOM   7741 C  CA  . ILE B 1 569 ? 128.061 158.664 111.620 1.00 59.10  ? 569 ILE A CA  1 
ATOM   7742 C  C   . ILE B 1 569 ? 128.385 159.716 110.568 1.00 59.10  ? 569 ILE A C   1 
ATOM   7743 O  O   . ILE B 1 569 ? 128.901 159.400 109.490 1.00 59.10  ? 569 ILE A O   1 
ATOM   7744 C  CB  . ILE B 1 569 ? 126.569 158.281 111.599 1.00 59.10  ? 569 ILE A CB  1 
ATOM   7745 C  CG1 . ILE B 1 569 ? 126.357 156.938 112.294 1.00 59.10  ? 569 ILE A CG1 1 
ATOM   7746 C  CG2 . ILE B 1 569 ? 126.048 158.220 110.176 1.00 59.10  ? 569 ILE A CG2 1 
ATOM   7747 C  CD1 . ILE B 1 569 ? 126.992 155.778 111.568 1.00 59.10  ? 569 ILE A CD1 1 
ATOM   7748 N  N   . CYS B 1 570 ? 128.100 160.983 110.868 1.00 60.39  ? 570 CYS A N   1 
ATOM   7749 C  CA  . CYS B 1 570 ? 128.341 162.032 109.884 1.00 60.39  ? 570 CYS A CA  1 
ATOM   7750 C  C   . CYS B 1 570 ? 129.825 162.345 109.723 1.00 60.39  ? 570 CYS A C   1 
ATOM   7751 O  O   . CYS B 1 570 ? 130.262 162.696 108.621 1.00 60.39  ? 570 CYS A O   1 
ATOM   7752 C  CB  . CYS B 1 570 ? 127.576 163.297 110.271 1.00 60.39  ? 570 CYS A CB  1 
ATOM   7753 S  SG  . CYS B 1 570 ? 127.696 164.638 109.067 1.00 60.39  ? 570 CYS A SG  1 
ATOM   7754 N  N   . THR B 1 571 ? 130.616 162.225 110.791 1.00 61.31  ? 571 THR A N   1 
ATOM   7755 C  CA  . THR B 1 571 ? 131.963 162.787 110.812 1.00 61.31  ? 571 THR A CA  1 
ATOM   7756 C  C   . THR B 1 571 ? 133.054 161.788 110.435 1.00 61.31  ? 571 THR A C   1 
ATOM   7757 O  O   . THR B 1 571 ? 133.737 161.975 109.425 1.00 61.31  ? 571 THR A O   1 
ATOM   7758 C  CB  . THR B 1 571 ? 132.255 163.377 112.198 1.00 61.31  ? 571 THR A CB  1 
ATOM   7759 O  OG1 . THR B 1 571 ? 131.309 164.413 112.487 1.00 61.31  ? 571 THR A OG1 1 
ATOM   7760 C  CG2 . THR B 1 571 ? 133.659 163.957 112.242 1.00 61.31  ? 571 THR A CG2 1 
ATOM   7761 N  N   . TRP B 1 572 ? 133.234 160.723 111.222 1.00 60.25  ? 572 TRP A N   1 
ATOM   7762 C  CA  . TRP B 1 572 ? 134.442 159.916 111.109 1.00 60.25  ? 572 TRP A CA  1 
ATOM   7763 C  C   . TRP B 1 572 ? 134.218 158.448 110.778 1.00 60.25  ? 572 TRP A C   1 
ATOM   7764 O  O   . TRP B 1 572 ? 135.178 157.780 110.380 1.00 60.25  ? 572 TRP A O   1 
ATOM   7765 C  CB  . TRP B 1 572 ? 135.274 160.008 112.402 1.00 60.25  ? 572 TRP A CB  1 
ATOM   7766 C  CG  . TRP B 1 572 ? 134.719 159.255 113.580 1.00 60.25  ? 572 TRP A CG  1 
ATOM   7767 C  CD1 . TRP B 1 572 ? 134.835 157.918 113.829 1.00 60.25  ? 572 TRP A CD1 1 
ATOM   7768 C  CD2 . TRP B 1 572 ? 133.987 159.804 114.682 1.00 60.25  ? 572 TRP A CD2 1 
ATOM   7769 N  NE1 . TRP B 1 572 ? 134.210 157.599 115.009 1.00 60.25  ? 572 TRP A NE1 1 
ATOM   7770 C  CE2 . TRP B 1 572 ? 133.682 158.740 115.553 1.00 60.25  ? 572 TRP A CE2 1 
ATOM   7771 C  CE3 . TRP B 1 572 ? 133.555 161.091 115.013 1.00 60.25  ? 572 TRP A CE3 1 
ATOM   7772 C  CZ2 . TRP B 1 572 ? 132.965 158.923 116.730 1.00 60.25  ? 572 TRP A CZ2 1 
ATOM   7773 C  CZ3 . TRP B 1 572 ? 132.845 161.271 116.184 1.00 60.25  ? 572 TRP A CZ3 1 
ATOM   7774 C  CH2 . TRP B 1 572 ? 132.556 160.193 117.028 1.00 60.25  ? 572 TRP A CH2 1 
ATOM   7775 N  N   . ILE B 1 573 ? 133.005 157.921 110.936 1.00 62.09  ? 573 ILE A N   1 
ATOM   7776 C  CA  . ILE B 1 573 ? 132.772 156.521 110.593 1.00 62.09  ? 573 ILE A CA  1 
ATOM   7777 C  C   . ILE B 1 573 ? 132.821 156.323 109.082 1.00 62.09  ? 573 ILE A C   1 
ATOM   7778 O  O   . ILE B 1 573 ? 133.332 155.307 108.590 1.00 62.09  ? 573 ILE A O   1 
ATOM   7779 C  CB  . ILE B 1 573 ? 131.440 156.039 111.194 1.00 62.09  ? 573 ILE A CB  1 
ATOM   7780 C  CG1 . ILE B 1 573 ? 131.475 156.161 112.717 1.00 62.09  ? 573 ILE A CG1 1 
ATOM   7781 C  CG2 . ILE B 1 573 ? 131.158 154.603 110.790 1.00 62.09  ? 573 ILE A CG2 1 
ATOM   7782 C  CD1 . ILE B 1 573 ? 130.277 155.558 113.406 1.00 62.09  ? 573 ILE A CD1 1 
ATOM   7783 N  N   . VAL B 1 574 ? 132.291 157.285 108.322 1.00 64.89  ? 574 VAL A N   1 
ATOM   7784 C  CA  . VAL B 1 574 ? 132.240 157.140 106.866 1.00 64.89  ? 574 VAL A CA  1 
ATOM   7785 C  C   . VAL B 1 574 ? 133.622 156.990 106.240 1.00 64.89  ? 574 VAL A C   1 
ATOM   7786 O  O   . VAL B 1 574 ? 133.804 156.079 105.416 1.00 64.89  ? 574 VAL A O   1 
ATOM   7787 C  CB  . VAL B 1 574 ? 131.439 158.300 106.247 1.00 64.89  ? 574 VAL A CB  1 
ATOM   7788 C  CG1 . VAL B 1 574 ? 131.474 158.213 104.734 1.00 64.89  ? 574 VAL A CG1 1 
ATOM   7789 C  CG2 . VAL B 1 574 ? 130.010 158.277 106.745 1.00 64.89  ? 574 VAL A CG2 1 
ATOM   7790 N  N   . PRO B 1 575 ? 134.621 157.828 106.555 1.00 66.31  ? 575 PRO A N   1 
ATOM   7791 C  CA  . PRO B 1 575 ? 135.928 157.656 105.896 1.00 66.31  ? 575 PRO A CA  1 
ATOM   7792 C  C   . PRO B 1 575 ? 136.548 156.288 106.117 1.00 66.31  ? 575 PRO A C   1 
ATOM   7793 O  O   . PRO B 1 575 ? 137.206 155.761 105.212 1.00 66.31  ? 575 PRO A O   1 
ATOM   7794 C  CB  . PRO B 1 575 ? 136.779 158.770 106.518 1.00 66.31  ? 575 PRO A CB  1 
ATOM   7795 C  CG  . PRO B 1 575 ? 135.801 159.805 106.914 1.00 66.31  ? 575 PRO A CG  1 
ATOM   7796 C  CD  . PRO B 1 575 ? 134.600 159.046 107.388 1.00 66.31  ? 575 PRO A CD  1 
ATOM   7797 N  N   . MET B 1 576 ? 136.359 155.694 107.293 1.00 62.83  ? 576 MET A N   1 
ATOM   7798 C  CA  . MET B 1 576 ? 136.972 154.405 107.582 1.00 62.83  ? 576 MET A CA  1 
ATOM   7799 C  C   . MET B 1 576 ? 136.098 153.224 107.185 1.00 62.83  ? 576 MET A C   1 
ATOM   7800 O  O   . MET B 1 576 ? 136.588 152.089 107.156 1.00 62.83  ? 576 MET A O   1 
ATOM   7801 C  CB  . MET B 1 576 ? 137.321 154.308 109.070 1.00 62.83  ? 576 MET A CB  1 
ATOM   7802 C  CG  . MET B 1 576 ? 136.125 154.321 109.999 1.00 62.83  ? 576 MET A CG  1 
ATOM   7803 S  SD  . MET B 1 576 ? 136.621 154.186 111.724 1.00 62.83  ? 576 MET A SD  1 
ATOM   7804 C  CE  . MET B 1 576 ? 137.134 152.472 111.784 1.00 62.83  ? 576 MET A CE  1 
ATOM   7805 N  N   . PHE B 1 577 ? 134.819 153.451 106.881 1.00 64.54  ? 577 PHE A N   1 
ATOM   7806 C  CA  . PHE B 1 577 ? 133.939 152.369 106.463 1.00 64.54  ? 577 PHE A CA  1 
ATOM   7807 C  C   . PHE B 1 577 ? 133.403 152.516 105.046 1.00 64.54  ? 577 PHE A C   1 
ATOM   7808 O  O   . PHE B 1 577 ? 132.763 151.581 104.551 1.00 64.54  ? 577 PHE A O   1 
ATOM   7809 C  CB  . PHE B 1 577 ? 132.757 152.237 107.434 1.00 64.54  ? 577 PHE A CB  1 
ATOM   7810 C  CG  . PHE B 1 577 ? 132.995 151.261 108.547 1.00 64.54  ? 577 PHE A CG  1 
ATOM   7811 C  CD1 . PHE B 1 577 ? 133.095 149.906 108.286 1.00 64.54  ? 577 PHE A CD1 1 
ATOM   7812 C  CD2 . PHE B 1 577 ? 133.117 151.695 109.855 1.00 64.54  ? 577 PHE A CD2 1 
ATOM   7813 C  CE1 . PHE B 1 577 ? 133.314 149.004 109.307 1.00 64.54  ? 577 PHE A CE1 1 
ATOM   7814 C  CE2 . PHE B 1 577 ? 133.335 150.797 110.880 1.00 64.54  ? 577 PHE A CE2 1 
ATOM   7815 C  CZ  . PHE B 1 577 ? 133.434 149.450 110.606 1.00 64.54  ? 577 PHE A CZ  1 
ATOM   7816 N  N   . ASP B 1 578 ? 133.648 153.648 104.383 1.00 67.22  ? 578 ASP A N   1 
ATOM   7817 C  CA  . ASP B 1 578 ? 133.140 153.907 103.035 1.00 67.22  ? 578 ASP A CA  1 
ATOM   7818 C  C   . ASP B 1 578 ? 131.621 153.750 102.982 1.00 67.22  ? 578 ASP A C   1 
ATOM   7819 O  O   . ASP B 1 578 ? 131.071 153.018 102.157 1.00 67.22  ? 578 ASP A O   1 
ATOM   7820 C  CB  . ASP B 1 578 ? 133.822 153.004 102.006 1.00 67.22  ? 578 ASP A CB  1 
ATOM   7821 C  CG  . ASP B 1 578 ? 135.216 153.478 101.648 1.00 67.22  ? 578 ASP A CG  1 
ATOM   7822 O  OD1 . ASP B 1 578 ? 135.859 154.130 102.497 1.00 67.22  ? 578 ASP A OD1 1 
ATOM   7823 O  OD2 . ASP B 1 578 ? 135.668 153.199 100.518 1.00 67.22  ? 578 ASP A OD2 1 
ATOM   7824 N  N   . LEU B 1 579 ? 130.939 154.452 103.890 1.00 65.26  ? 579 LEU A N   1 
ATOM   7825 C  CA  . LEU B 1 579 ? 129.488 154.331 103.985 1.00 65.26  ? 579 LEU A CA  1 
ATOM   7826 C  C   . LEU B 1 579 ? 128.782 154.969 102.795 1.00 65.26  ? 579 LEU A C   1 
ATOM   7827 O  O   . LEU B 1 579 ? 127.696 154.522 102.411 1.00 65.26  ? 579 LEU A O   1 
ATOM   7828 C  CB  . LEU B 1 579 ? 128.997 154.958 105.290 1.00 65.26  ? 579 LEU A CB  1 
ATOM   7829 C  CG  . LEU B 1 579 ? 129.405 154.236 106.576 1.00 65.26  ? 579 LEU A CG  1 
ATOM   7830 C  CD1 . LEU B 1 579 ? 128.862 154.953 107.798 1.00 65.26  ? 579 LEU A CD1 1 
ATOM   7831 C  CD2 . LEU B 1 579 ? 128.936 152.797 106.550 1.00 65.26  ? 579 LEU A CD2 1 
ATOM   7832 N  N   . TYR B 1 580 ? 129.371 156.011 102.205 1.00 68.26  ? 580 TYR A N   1 
ATOM   7833 C  CA  . TYR B 1 580 ? 128.703 156.712 101.114 1.00 68.26  ? 580 TYR A CA  1 
ATOM   7834 C  C   . TYR B 1 580 ? 128.688 155.880 99.837  1.00 68.26  ? 580 TYR A C   1 
ATOM   7835 O  O   . TYR B 1 580 ? 127.773 156.011 99.017  1.00 68.26  ? 580 TYR A O   1 
ATOM   7836 C  CB  . TYR B 1 580 ? 129.375 158.062 100.869 1.00 68.26  ? 580 TYR A CB  1 
ATOM   7837 C  CG  . TYR B 1 580 ? 129.110 159.071 101.962 1.00 68.26  ? 580 TYR A CG  1 
ATOM   7838 C  CD1 . TYR B 1 580 ? 127.984 158.968 102.767 1.00 68.26  ? 580 TYR A CD1 1 
ATOM   7839 C  CD2 . TYR B 1 580 ? 129.984 160.125 102.189 1.00 68.26  ? 580 TYR A CD2 1 
ATOM   7840 C  CE1 . TYR B 1 580 ? 127.736 159.885 103.769 1.00 68.26  ? 580 TYR A CE1 1 
ATOM   7841 C  CE2 . TYR B 1 580 ? 129.744 161.047 103.190 1.00 68.26  ? 580 TYR A CE2 1 
ATOM   7842 C  CZ  . TYR B 1 580 ? 128.619 160.922 103.976 1.00 68.26  ? 580 TYR A CZ  1 
ATOM   7843 O  OH  . TYR B 1 580 ? 128.373 161.837 104.974 1.00 68.26  ? 580 TYR A OH  1 
ATOM   7844 N  N   . THR B 1 581 ? 129.688 155.024 99.648  1.00 70.25  ? 581 THR A N   1 
ATOM   7845 C  CA  . THR B 1 581 ? 129.798 154.223 98.437  1.00 70.25  ? 581 THR A CA  1 
ATOM   7846 C  C   . THR B 1 581 ? 129.198 152.842 98.664  1.00 70.25  ? 581 THR A C   1 
ATOM   7847 O  O   . THR B 1 581 ? 129.498 152.184 99.666  1.00 70.25  ? 581 THR A O   1 
ATOM   7848 C  CB  . THR B 1 581 ? 131.259 154.100 98.005  1.00 70.25  ? 581 THR A CB  1 
ATOM   7849 O  OG1 . THR B 1 581 ? 131.793 155.405 97.746  1.00 70.25  ? 581 THR A OG1 1 
ATOM   7850 C  CG2 . THR B 1 581 ? 131.375 153.257 96.745  1.00 70.25  ? 581 THR A CG2 1 
ATOM   7851 N  N   . TYR B 1 582 ? 128.349 152.412 97.737  1.00 73.77  ? 582 TYR A N   1 
ATOM   7852 C  CA  . TYR B 1 582 ? 127.752 151.090 97.829  1.00 73.77  ? 582 TYR A CA  1 
ATOM   7853 C  C   . TYR B 1 582 ? 128.841 150.023 97.749  1.00 73.77  ? 582 TYR A C   1 
ATOM   7854 O  O   . TYR B 1 582 ? 129.772 150.145 96.944  1.00 73.77  ? 582 TYR A O   1 
ATOM   7855 C  CB  . TYR B 1 582 ? 126.732 150.888 96.707  1.00 73.77  ? 582 TYR A CB  1 
ATOM   7856 C  CG  . TYR B 1 582 ? 125.720 149.796 96.971  1.00 73.77  ? 582 TYR A CG  1 
ATOM   7857 C  CD1 . TYR B 1 582 ? 124.661 149.998 97.844  1.00 73.77  ? 582 TYR A CD1 1 
ATOM   7858 C  CD2 . TYR B 1 582 ? 125.822 148.563 96.342  1.00 73.77  ? 582 TYR A CD2 1 
ATOM   7859 C  CE1 . TYR B 1 582 ? 123.735 149.003 98.084  1.00 73.77  ? 582 TYR A CE1 1 
ATOM   7860 C  CE2 . TYR B 1 582 ? 124.901 147.563 96.577  1.00 73.77  ? 582 TYR A CE2 1 
ATOM   7861 C  CZ  . TYR B 1 582 ? 123.860 147.788 97.449  1.00 73.77  ? 582 TYR A CZ  1 
ATOM   7862 O  OH  . TYR B 1 582 ? 122.940 146.795 97.686  1.00 73.77  ? 582 TYR A OH  1 
ATOM   7863 N  N   . PRO B 1 583 ? 128.762 148.971 98.558  1.00 78.05  ? 583 PRO A N   1 
ATOM   7864 C  CA  . PRO B 1 583 ? 129.823 147.964 98.582  1.00 78.05  ? 583 PRO A CA  1 
ATOM   7865 C  C   . PRO B 1 583 ? 129.601 146.851 97.568  1.00 78.05  ? 583 PRO A C   1 
ATOM   7866 O  O   . PRO B 1 583 ? 128.506 146.653 97.039  1.00 78.05  ? 583 PRO A O   1 
ATOM   7867 C  CB  . PRO B 1 583 ? 129.745 147.413 100.013 1.00 78.05  ? 583 PRO A CB  1 
ATOM   7868 C  CG  . PRO B 1 583 ? 128.347 147.732 100.492 1.00 78.05  ? 583 PRO A CG  1 
ATOM   7869 C  CD  . PRO B 1 583 ? 127.679 148.645 99.498  1.00 78.05  ? 583 PRO A CD  1 
ATOM   7870 N  N   . SER B 1 584 ? 130.684 146.119 97.307  1.00 82.78  ? 584 SER A N   1 
ATOM   7871 C  CA  . SER B 1 584 ? 130.615 144.978 96.403  1.00 82.78  ? 584 SER A CA  1 
ATOM   7872 C  C   . SER B 1 584 ? 129.970 143.765 97.059  1.00 82.78  ? 584 SER A C   1 
ATOM   7873 O  O   . SER B 1 584 ? 129.329 142.964 96.370  1.00 82.78  ? 584 SER A O   1 
ATOM   7874 C  CB  . SER B 1 584 ? 132.015 144.621 95.902  1.00 82.78  ? 584 SER A CB  1 
ATOM   7875 O  OG  . SER B 1 584 ? 132.838 144.174 96.964  1.00 82.78  ? 584 SER A OG  1 
ATOM   7876 N  N   . TRP B 1 585 ? 130.128 143.607 98.376  1.00 78.81  ? 585 TRP A N   1 
ATOM   7877 C  CA  . TRP B 1 585 ? 129.549 142.449 99.050  1.00 78.81  ? 585 TRP A CA  1 
ATOM   7878 C  C   . TRP B 1 585 ? 128.029 142.528 99.104  1.00 78.81  ? 585 TRP A C   1 
ATOM   7879 O  O   . TRP B 1 585 ? 127.358 141.490 99.164  1.00 78.81  ? 585 TRP A O   1 
ATOM   7880 C  CB  . TRP B 1 585 ? 130.133 142.310 100.458 1.00 78.81  ? 585 TRP A CB  1 
ATOM   7881 C  CG  . TRP B 1 585 ? 129.768 143.413 101.408 1.00 78.81  ? 585 TRP A CG  1 
ATOM   7882 C  CD1 . TRP B 1 585 ? 128.580 143.577 102.060 1.00 78.81  ? 585 TRP A CD1 1 
ATOM   7883 C  CD2 . TRP B 1 585 ? 130.608 144.494 101.832 1.00 78.81  ? 585 TRP A CD2 1 
ATOM   7884 N  NE1 . TRP B 1 585 ? 128.624 144.697 102.853 1.00 78.81  ? 585 TRP A NE1 1 
ATOM   7885 C  CE2 . TRP B 1 585 ? 129.859 145.277 102.732 1.00 78.81  ? 585 TRP A CE2 1 
ATOM   7886 C  CE3 . TRP B 1 585 ? 131.918 144.876 101.534 1.00 78.81  ? 585 TRP A CE3 1 
ATOM   7887 C  CZ2 . TRP B 1 585 ? 130.376 146.419 103.336 1.00 78.81  ? 585 TRP A CZ2 1 
ATOM   7888 C  CZ3 . TRP B 1 585 ? 132.430 146.012 102.134 1.00 78.81  ? 585 TRP A CZ3 1 
ATOM   7889 C  CH2 . TRP B 1 585 ? 131.660 146.770 103.024 1.00 78.81  ? 585 TRP A CH2 1 
ATOM   7890 N  N   . ALA B 1 586 ? 127.471 143.735 99.089  1.00 81.06  ? 586 ALA A N   1 
ATOM   7891 C  CA  . ALA B 1 586 ? 126.027 143.888 99.071  1.00 81.06  ? 586 ALA A CA  1 
ATOM   7892 C  C   . ALA B 1 586 ? 125.462 143.422 97.729  1.00 81.06  ? 586 ALA A C   1 
ATOM   7893 O  O   . ALA B 1 586 ? 126.099 143.591 96.686  1.00 81.06  ? 586 ALA A O   1 
ATOM   7894 C  CB  . ALA B 1 586 ? 125.644 145.344 99.322  1.00 81.06  ? 586 ALA A CB  1 
ATOM   7895 N  N   . PRO B 1 587 ? 124.269 142.832 97.727  1.00 80.55  ? 587 PRO A N   1 
ATOM   7896 C  CA  . PRO B 1 587 ? 123.690 142.356 96.468  1.00 80.55  ? 587 PRO A CA  1 
ATOM   7897 C  C   . PRO B 1 587 ? 123.219 143.511 95.598  1.00 80.55  ? 587 PRO A C   1 
ATOM   7898 O  O   . PRO B 1 587 ? 122.940 144.615 96.071  1.00 80.55  ? 587 PRO A O   1 
ATOM   7899 C  CB  . PRO B 1 587 ? 122.516 141.479 96.912  1.00 80.55  ? 587 PRO A CB  1 
ATOM   7900 C  CG  . PRO B 1 587 ? 122.217 141.874 98.320  1.00 80.55  ? 587 PRO A CG  1 
ATOM   7901 C  CD  . PRO B 1 587 ? 123.328 142.729 98.855  1.00 80.55  ? 587 PRO A CD  1 
ATOM   7902 N  N   . ALA B 1 588 ? 123.137 143.236 94.301  1.00 88.21  ? 588 ALA A N   1 
ATOM   7903 C  CA  . ALA B 1 588 ? 122.714 144.237 93.329  1.00 88.21  ? 588 ALA A CA  1 
ATOM   7904 C  C   . ALA B 1 588 ? 121.228 144.546 93.472  1.00 88.21  ? 588 ALA A C   1 
ATOM   7905 O  O   . ALA B 1 588 ? 120.764 145.610 93.064  1.00 88.21  ? 588 ALA A O   1 
ATOM   7906 C  CB  . ALA B 1 588 ? 123.024 143.767 91.917  1.00 88.21  ? 588 ALA A CB  1 
HETATM 7907 S  S   . SO4 C 2 .   ? 127.132 109.534 128.484 1.00 62.29  ? 601 SO4 B S   1 
HETATM 7908 O  O1  . SO4 C 2 .   ? 128.050 109.956 127.432 1.00 62.29  ? 601 SO4 B O1  1 
HETATM 7909 O  O2  . SO4 C 2 .   ? 125.771 109.914 128.122 1.00 62.29  ? 601 SO4 B O2  1 
HETATM 7910 O  O3  . SO4 C 2 .   ? 127.500 110.176 129.741 1.00 62.29  ? 601 SO4 B O3  1 
HETATM 7911 O  O4  . SO4 C 2 .   ? 127.211 108.087 128.637 1.00 62.29  ? 601 SO4 B O4  1 
HETATM 7912 NA NA  . NA  D 3 .   ? 121.939 107.533 129.177 1.00 51.26  ? 602 NA  B NA  1 
HETATM 7913 S  S   . SO4 E 2 .   ? 124.085 141.686 128.483 1.00 62.44  ? 601 SO4 A S   1 
HETATM 7914 O  O1  . SO4 E 2 .   ? 123.168 141.261 127.432 1.00 62.44  ? 601 SO4 A O1  1 
HETATM 7915 O  O2  . SO4 E 2 .   ? 125.447 141.309 128.122 1.00 62.44  ? 601 SO4 A O2  1 
HETATM 7916 O  O3  . SO4 E 2 .   ? 123.719 141.046 129.742 1.00 62.44  ? 601 SO4 A O3  1 
HETATM 7917 O  O4  . SO4 E 2 .   ? 124.003 143.134 128.634 1.00 62.44  ? 601 SO4 A O4  1 
HETATM 7918 NA NA  . NA  F 3 .   ? 129.280 143.688 129.179 1.00 50.75  ? 602 NA  A NA  1 
# 
