data_8Y5U
# 
_entry.id   8Y5U 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Y5U         pdb_00008y5u 10.2210/pdb8y5u/pdb 
WWPDB D_1300044941 ?            ?                   
EMDB  EMD-38953    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Y5U 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'human NaS1 intermediate state 1' 
_pdbx_database_related.db_id          EMD-38953 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhang.ss@phytovent.com 
_pdbx_contact_author.name_first         Sensen 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8827-3959 
# 
_audit_author.name               'Zhang, S.S.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0001-8827-3959 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Sci Adv' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2375-2548 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            10 
_citation.language                  ? 
_citation.page_first                eado6778 
_citation.page_last                 ? 
_citation.title                     'human NaS1 intermediate state 1' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/sciadv.ado6778 
_citation.pdbx_database_id_PubMed   39576865 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
_citation_author.citation_id        primary 
_citation_author.name               'Zhang, S.S.' 
_citation_author.ordinal            1 
_citation_author.identifier_ORCID   0000-0001-8827-3959 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Solute carrier family 13 member 1' 66184.859 2 ? ? ? ? 
2 non-polymer syn 'SODIUM ION'                        22.990    3 ? ? ? ? 
3 non-polymer syn 'SULFATE ION'                       96.063    2 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Renal sodium/sulfate cotransporter,Na(+)/sulfate cotransporter,hNaSi-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASA
YFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIIN
AEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT
CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGK
TKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIP
AKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM
VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIV
GVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASA
YFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIIN
AEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT
CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGK
TKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIP
AKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM
VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIV
GVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SODIUM ION'  NA  
3 'SULFATE ION' SO4 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   PHE n 
1 4   PHE n 
1 5   SER n 
1 6   TYR n 
1 7   ILE n 
1 8   LEU n 
1 9   VAL n 
1 10  TYR n 
1 11  ARG n 
1 12  ARG n 
1 13  PHE n 
1 14  LEU n 
1 15  PHE n 
1 16  VAL n 
1 17  VAL n 
1 18  PHE n 
1 19  THR n 
1 20  VAL n 
1 21  LEU n 
1 22  VAL n 
1 23  LEU n 
1 24  LEU n 
1 25  PRO n 
1 26  LEU n 
1 27  PRO n 
1 28  ILE n 
1 29  VAL n 
1 30  LEU n 
1 31  HIS n 
1 32  THR n 
1 33  LYS n 
1 34  GLU n 
1 35  ALA n 
1 36  GLU n 
1 37  CYS n 
1 38  ALA n 
1 39  TYR n 
1 40  THR n 
1 41  LEU n 
1 42  PHE n 
1 43  VAL n 
1 44  VAL n 
1 45  ALA n 
1 46  THR n 
1 47  PHE n 
1 48  TRP n 
1 49  LEU n 
1 50  THR n 
1 51  GLU n 
1 52  ALA n 
1 53  LEU n 
1 54  PRO n 
1 55  LEU n 
1 56  SER n 
1 57  VAL n 
1 58  THR n 
1 59  ALA n 
1 60  LEU n 
1 61  LEU n 
1 62  PRO n 
1 63  SER n 
1 64  LEU n 
1 65  MET n 
1 66  LEU n 
1 67  PRO n 
1 68  MET n 
1 69  PHE n 
1 70  GLY n 
1 71  ILE n 
1 72  MET n 
1 73  PRO n 
1 74  SER n 
1 75  LYS n 
1 76  LYS n 
1 77  VAL n 
1 78  ALA n 
1 79  SER n 
1 80  ALA n 
1 81  TYR n 
1 82  PHE n 
1 83  LYS n 
1 84  ASP n 
1 85  PHE n 
1 86  HIS n 
1 87  LEU n 
1 88  LEU n 
1 89  LEU n 
1 90  ILE n 
1 91  GLY n 
1 92  VAL n 
1 93  ILE n 
1 94  CYS n 
1 95  LEU n 
1 96  ALA n 
1 97  THR n 
1 98  SER n 
1 99  ILE n 
1 100 GLU n 
1 101 LYS n 
1 102 TRP n 
1 103 ASN n 
1 104 LEU n 
1 105 HIS n 
1 106 LYS n 
1 107 ARG n 
1 108 ILE n 
1 109 ALA n 
1 110 LEU n 
1 111 LYS n 
1 112 MET n 
1 113 VAL n 
1 114 MET n 
1 115 MET n 
1 116 VAL n 
1 117 GLY n 
1 118 VAL n 
1 119 ASN n 
1 120 PRO n 
1 121 ALA n 
1 122 TRP n 
1 123 LEU n 
1 124 THR n 
1 125 LEU n 
1 126 GLY n 
1 127 PHE n 
1 128 MET n 
1 129 SER n 
1 130 SER n 
1 131 THR n 
1 132 ALA n 
1 133 PHE n 
1 134 LEU n 
1 135 SER n 
1 136 MET n 
1 137 TRP n 
1 138 LEU n 
1 139 SER n 
1 140 ASN n 
1 141 THR n 
1 142 SER n 
1 143 THR n 
1 144 ALA n 
1 145 ALA n 
1 146 MET n 
1 147 VAL n 
1 148 MET n 
1 149 PRO n 
1 150 ILE n 
1 151 ALA n 
1 152 GLU n 
1 153 ALA n 
1 154 VAL n 
1 155 VAL n 
1 156 GLN n 
1 157 GLN n 
1 158 ILE n 
1 159 ILE n 
1 160 ASN n 
1 161 ALA n 
1 162 GLU n 
1 163 ALA n 
1 164 GLU n 
1 165 VAL n 
1 166 GLU n 
1 167 ALA n 
1 168 THR n 
1 169 GLN n 
1 170 MET n 
1 171 THR n 
1 172 TYR n 
1 173 PHE n 
1 174 ASN n 
1 175 GLY n 
1 176 SER n 
1 177 THR n 
1 178 ASN n 
1 179 HIS n 
1 180 GLY n 
1 181 LEU n 
1 182 GLU n 
1 183 ILE n 
1 184 ASP n 
1 185 GLU n 
1 186 SER n 
1 187 VAL n 
1 188 ASN n 
1 189 GLY n 
1 190 HIS n 
1 191 GLU n 
1 192 ILE n 
1 193 ASN n 
1 194 GLU n 
1 195 ARG n 
1 196 LYS n 
1 197 GLU n 
1 198 LYS n 
1 199 THR n 
1 200 LYS n 
1 201 PRO n 
1 202 VAL n 
1 203 PRO n 
1 204 GLY n 
1 205 TYR n 
1 206 ASN n 
1 207 ASN n 
1 208 ASP n 
1 209 THR n 
1 210 GLY n 
1 211 LYS n 
1 212 ILE n 
1 213 SER n 
1 214 SER n 
1 215 LYS n 
1 216 VAL n 
1 217 GLU n 
1 218 LEU n 
1 219 GLU n 
1 220 LYS n 
1 221 ASN n 
1 222 SER n 
1 223 GLY n 
1 224 MET n 
1 225 ARG n 
1 226 THR n 
1 227 LYS n 
1 228 TYR n 
1 229 ARG n 
1 230 THR n 
1 231 LYS n 
1 232 LYS n 
1 233 GLY n 
1 234 HIS n 
1 235 VAL n 
1 236 THR n 
1 237 ARG n 
1 238 LYS n 
1 239 LEU n 
1 240 THR n 
1 241 CYS n 
1 242 LEU n 
1 243 CYS n 
1 244 ILE n 
1 245 ALA n 
1 246 TYR n 
1 247 SER n 
1 248 SER n 
1 249 THR n 
1 250 ILE n 
1 251 GLY n 
1 252 GLY n 
1 253 LEU n 
1 254 THR n 
1 255 THR n 
1 256 ILE n 
1 257 THR n 
1 258 GLY n 
1 259 THR n 
1 260 SER n 
1 261 THR n 
1 262 ASN n 
1 263 LEU n 
1 264 ILE n 
1 265 PHE n 
1 266 ALA n 
1 267 GLU n 
1 268 TYR n 
1 269 PHE n 
1 270 ASN n 
1 271 THR n 
1 272 ARG n 
1 273 TYR n 
1 274 PRO n 
1 275 ASP n 
1 276 CYS n 
1 277 ARG n 
1 278 CYS n 
1 279 LEU n 
1 280 ASN n 
1 281 PHE n 
1 282 GLY n 
1 283 SER n 
1 284 TRP n 
1 285 PHE n 
1 286 THR n 
1 287 PHE n 
1 288 SER n 
1 289 PHE n 
1 290 PRO n 
1 291 ALA n 
1 292 ALA n 
1 293 LEU n 
1 294 ILE n 
1 295 ILE n 
1 296 LEU n 
1 297 LEU n 
1 298 LEU n 
1 299 SER n 
1 300 TRP n 
1 301 ILE n 
1 302 TRP n 
1 303 LEU n 
1 304 GLN n 
1 305 TRP n 
1 306 LEU n 
1 307 PHE n 
1 308 LEU n 
1 309 GLY n 
1 310 PHE n 
1 311 ASN n 
1 312 PHE n 
1 313 LYS n 
1 314 GLU n 
1 315 MET n 
1 316 PHE n 
1 317 LYS n 
1 318 CYS n 
1 319 GLY n 
1 320 LYS n 
1 321 THR n 
1 322 LYS n 
1 323 THR n 
1 324 VAL n 
1 325 GLN n 
1 326 GLN n 
1 327 LYS n 
1 328 ALA n 
1 329 CYS n 
1 330 ALA n 
1 331 GLU n 
1 332 VAL n 
1 333 ILE n 
1 334 LYS n 
1 335 GLN n 
1 336 GLU n 
1 337 TYR n 
1 338 GLN n 
1 339 LYS n 
1 340 LEU n 
1 341 GLY n 
1 342 PRO n 
1 343 ILE n 
1 344 ARG n 
1 345 TYR n 
1 346 GLN n 
1 347 GLU n 
1 348 ILE n 
1 349 VAL n 
1 350 THR n 
1 351 LEU n 
1 352 VAL n 
1 353 LEU n 
1 354 PHE n 
1 355 ILE n 
1 356 ILE n 
1 357 MET n 
1 358 ALA n 
1 359 LEU n 
1 360 LEU n 
1 361 TRP n 
1 362 PHE n 
1 363 SER n 
1 364 ARG n 
1 365 ASP n 
1 366 PRO n 
1 367 GLY n 
1 368 PHE n 
1 369 VAL n 
1 370 PRO n 
1 371 GLY n 
1 372 TRP n 
1 373 SER n 
1 374 ALA n 
1 375 LEU n 
1 376 PHE n 
1 377 SER n 
1 378 GLU n 
1 379 TYR n 
1 380 PRO n 
1 381 GLY n 
1 382 PHE n 
1 383 ALA n 
1 384 THR n 
1 385 ASP n 
1 386 SER n 
1 387 THR n 
1 388 VAL n 
1 389 ALA n 
1 390 LEU n 
1 391 LEU n 
1 392 ILE n 
1 393 GLY n 
1 394 LEU n 
1 395 LEU n 
1 396 PHE n 
1 397 PHE n 
1 398 LEU n 
1 399 ILE n 
1 400 PRO n 
1 401 ALA n 
1 402 LYS n 
1 403 THR n 
1 404 LEU n 
1 405 THR n 
1 406 LYS n 
1 407 THR n 
1 408 THR n 
1 409 PRO n 
1 410 THR n 
1 411 GLY n 
1 412 GLU n 
1 413 ILE n 
1 414 VAL n 
1 415 ALA n 
1 416 PHE n 
1 417 ASP n 
1 418 TYR n 
1 419 SER n 
1 420 PRO n 
1 421 LEU n 
1 422 ILE n 
1 423 THR n 
1 424 TRP n 
1 425 LYS n 
1 426 GLU n 
1 427 PHE n 
1 428 GLN n 
1 429 SER n 
1 430 PHE n 
1 431 MET n 
1 432 PRO n 
1 433 TRP n 
1 434 ASP n 
1 435 ILE n 
1 436 ALA n 
1 437 ILE n 
1 438 LEU n 
1 439 VAL n 
1 440 GLY n 
1 441 GLY n 
1 442 GLY n 
1 443 PHE n 
1 444 ALA n 
1 445 LEU n 
1 446 ALA n 
1 447 ASP n 
1 448 GLY n 
1 449 CYS n 
1 450 GLU n 
1 451 GLU n 
1 452 SER n 
1 453 GLY n 
1 454 LEU n 
1 455 SER n 
1 456 LYS n 
1 457 TRP n 
1 458 ILE n 
1 459 GLY n 
1 460 ASN n 
1 461 LYS n 
1 462 LEU n 
1 463 SER n 
1 464 PRO n 
1 465 LEU n 
1 466 GLY n 
1 467 SER n 
1 468 LEU n 
1 469 PRO n 
1 470 ALA n 
1 471 TRP n 
1 472 LEU n 
1 473 ILE n 
1 474 ILE n 
1 475 LEU n 
1 476 ILE n 
1 477 SER n 
1 478 SER n 
1 479 LEU n 
1 480 MET n 
1 481 VAL n 
1 482 THR n 
1 483 SER n 
1 484 LEU n 
1 485 THR n 
1 486 GLU n 
1 487 VAL n 
1 488 ALA n 
1 489 SER n 
1 490 ASN n 
1 491 PRO n 
1 492 ALA n 
1 493 THR n 
1 494 ILE n 
1 495 THR n 
1 496 LEU n 
1 497 PHE n 
1 498 LEU n 
1 499 PRO n 
1 500 ILE n 
1 501 LEU n 
1 502 SER n 
1 503 PRO n 
1 504 LEU n 
1 505 ALA n 
1 506 GLU n 
1 507 ALA n 
1 508 ILE n 
1 509 HIS n 
1 510 VAL n 
1 511 ASN n 
1 512 PRO n 
1 513 LEU n 
1 514 TYR n 
1 515 ILE n 
1 516 LEU n 
1 517 ILE n 
1 518 PRO n 
1 519 SER n 
1 520 THR n 
1 521 LEU n 
1 522 CYS n 
1 523 THR n 
1 524 SER n 
1 525 PHE n 
1 526 ALA n 
1 527 PHE n 
1 528 LEU n 
1 529 LEU n 
1 530 PRO n 
1 531 VAL n 
1 532 ALA n 
1 533 ASN n 
1 534 PRO n 
1 535 PRO n 
1 536 ASN n 
1 537 ALA n 
1 538 ILE n 
1 539 VAL n 
1 540 PHE n 
1 541 SER n 
1 542 TYR n 
1 543 GLY n 
1 544 HIS n 
1 545 LEU n 
1 546 LYS n 
1 547 VAL n 
1 548 ILE n 
1 549 ASP n 
1 550 MET n 
1 551 VAL n 
1 552 LYS n 
1 553 ALA n 
1 554 GLY n 
1 555 LEU n 
1 556 GLY n 
1 557 VAL n 
1 558 ASN n 
1 559 ILE n 
1 560 VAL n 
1 561 GLY n 
1 562 VAL n 
1 563 ALA n 
1 564 VAL n 
1 565 VAL n 
1 566 MET n 
1 567 LEU n 
1 568 GLY n 
1 569 ILE n 
1 570 CYS n 
1 571 THR n 
1 572 TRP n 
1 573 ILE n 
1 574 VAL n 
1 575 PRO n 
1 576 MET n 
1 577 PHE n 
1 578 ASP n 
1 579 LEU n 
1 580 TYR n 
1 581 THR n 
1 582 TYR n 
1 583 PRO n 
1 584 SER n 
1 585 TRP n 
1 586 ALA n 
1 587 PRO n 
1 588 ALA n 
1 589 MET n 
1 590 SER n 
1 591 ASN n 
1 592 GLU n 
1 593 THR n 
1 594 MET n 
1 595 PRO n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   595 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'SLC13A1, NAS1, NASI1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            HEK293F 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
NA  non-polymer         . 'SODIUM ION'    ? 'Na 1'           22.990  
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   LYS 2   2   2   LYS LYS A . n 
A 1 3   PHE 3   3   3   PHE PHE A . n 
A 1 4   PHE 4   4   4   PHE PHE A . n 
A 1 5   SER 5   5   5   SER SER A . n 
A 1 6   TYR 6   6   6   TYR TYR A . n 
A 1 7   ILE 7   7   7   ILE ILE A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   VAL 9   9   9   VAL VAL A . n 
A 1 10  TYR 10  10  10  TYR TYR A . n 
A 1 11  ARG 11  11  11  ARG ARG A . n 
A 1 12  ARG 12  12  12  ARG ARG A . n 
A 1 13  PHE 13  13  13  PHE PHE A . n 
A 1 14  LEU 14  14  14  LEU LEU A . n 
A 1 15  PHE 15  15  15  PHE PHE A . n 
A 1 16  VAL 16  16  16  VAL VAL A . n 
A 1 17  VAL 17  17  17  VAL VAL A . n 
A 1 18  PHE 18  18  18  PHE PHE A . n 
A 1 19  THR 19  19  19  THR THR A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  LEU 21  21  21  LEU LEU A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  PRO 25  25  25  PRO PRO A . n 
A 1 26  LEU 26  26  26  LEU LEU A . n 
A 1 27  PRO 27  27  27  PRO PRO A . n 
A 1 28  ILE 28  28  28  ILE ILE A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  HIS 31  31  31  HIS HIS A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  LYS 33  33  33  LYS LYS A . n 
A 1 34  GLU 34  34  34  GLU GLU A . n 
A 1 35  ALA 35  35  35  ALA ALA A . n 
A 1 36  GLU 36  36  36  GLU GLU A . n 
A 1 37  CYS 37  37  37  CYS CYS A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  TYR 39  39  39  TYR TYR A . n 
A 1 40  THR 40  40  40  THR THR A . n 
A 1 41  LEU 41  41  41  LEU LEU A . n 
A 1 42  PHE 42  42  42  PHE PHE A . n 
A 1 43  VAL 43  43  43  VAL VAL A . n 
A 1 44  VAL 44  44  44  VAL VAL A . n 
A 1 45  ALA 45  45  45  ALA ALA A . n 
A 1 46  THR 46  46  46  THR THR A . n 
A 1 47  PHE 47  47  47  PHE PHE A . n 
A 1 48  TRP 48  48  48  TRP TRP A . n 
A 1 49  LEU 49  49  49  LEU LEU A . n 
A 1 50  THR 50  50  50  THR THR A . n 
A 1 51  GLU 51  51  51  GLU GLU A . n 
A 1 52  ALA 52  52  52  ALA ALA A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  PRO 54  54  54  PRO PRO A . n 
A 1 55  LEU 55  55  55  LEU LEU A . n 
A 1 56  SER 56  56  56  SER SER A . n 
A 1 57  VAL 57  57  57  VAL VAL A . n 
A 1 58  THR 58  58  58  THR THR A . n 
A 1 59  ALA 59  59  59  ALA ALA A . n 
A 1 60  LEU 60  60  60  LEU LEU A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  PRO 62  62  62  PRO PRO A . n 
A 1 63  SER 63  63  63  SER SER A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  MET 65  65  65  MET MET A . n 
A 1 66  LEU 66  66  66  LEU LEU A . n 
A 1 67  PRO 67  67  67  PRO PRO A . n 
A 1 68  MET 68  68  68  MET MET A . n 
A 1 69  PHE 69  69  69  PHE PHE A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  ILE 71  71  71  ILE ILE A . n 
A 1 72  MET 72  72  72  MET MET A . n 
A 1 73  PRO 73  73  73  PRO PRO A . n 
A 1 74  SER 74  74  74  SER SER A . n 
A 1 75  LYS 75  75  75  LYS LYS A . n 
A 1 76  LYS 76  76  76  LYS LYS A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  ALA 78  78  78  ALA ALA A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  ALA 80  80  80  ALA ALA A . n 
A 1 81  TYR 81  81  81  TYR TYR A . n 
A 1 82  PHE 82  82  82  PHE PHE A . n 
A 1 83  LYS 83  83  83  LYS LYS A . n 
A 1 84  ASP 84  84  84  ASP ASP A . n 
A 1 85  PHE 85  85  85  PHE PHE A . n 
A 1 86  HIS 86  86  86  HIS HIS A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  ILE 90  90  90  ILE ILE A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  ILE 93  93  93  ILE ILE A . n 
A 1 94  CYS 94  94  94  CYS CYS A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  ALA 96  96  96  ALA ALA A . n 
A 1 97  THR 97  97  97  THR THR A . n 
A 1 98  SER 98  98  98  SER SER A . n 
A 1 99  ILE 99  99  99  ILE ILE A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 LYS 101 101 101 LYS LYS A . n 
A 1 102 TRP 102 102 102 TRP TRP A . n 
A 1 103 ASN 103 103 103 ASN ASN A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 HIS 105 105 105 HIS HIS A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 ARG 107 107 107 ARG ARG A . n 
A 1 108 ILE 108 108 108 ILE ILE A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 LYS 111 111 111 LYS LYS A . n 
A 1 112 MET 112 112 112 MET MET A . n 
A 1 113 VAL 113 113 113 VAL VAL A . n 
A 1 114 MET 114 114 114 MET MET A . n 
A 1 115 MET 115 115 115 MET MET A . n 
A 1 116 VAL 116 116 116 VAL VAL A . n 
A 1 117 GLY 117 117 117 GLY GLY A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 ASN 119 119 119 ASN ASN A . n 
A 1 120 PRO 120 120 120 PRO PRO A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 TRP 122 122 122 TRP TRP A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 THR 124 124 124 THR THR A . n 
A 1 125 LEU 125 125 125 LEU LEU A . n 
A 1 126 GLY 126 126 126 GLY GLY A . n 
A 1 127 PHE 127 127 127 PHE PHE A . n 
A 1 128 MET 128 128 128 MET MET A . n 
A 1 129 SER 129 129 129 SER SER A . n 
A 1 130 SER 130 130 130 SER SER A . n 
A 1 131 THR 131 131 131 THR THR A . n 
A 1 132 ALA 132 132 132 ALA ALA A . n 
A 1 133 PHE 133 133 133 PHE PHE A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 SER 135 135 135 SER SER A . n 
A 1 136 MET 136 136 136 MET MET A . n 
A 1 137 TRP 137 137 137 TRP TRP A . n 
A 1 138 LEU 138 138 138 LEU LEU A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 ASN 140 140 140 ASN ASN A . n 
A 1 141 THR 141 141 141 THR THR A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 MET 146 146 146 MET MET A . n 
A 1 147 VAL 147 147 147 VAL VAL A . n 
A 1 148 MET 148 148 148 MET MET A . n 
A 1 149 PRO 149 149 149 PRO PRO A . n 
A 1 150 ILE 150 150 150 ILE ILE A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 GLU 152 152 152 GLU GLU A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 VAL 154 154 154 VAL VAL A . n 
A 1 155 VAL 155 155 155 VAL VAL A . n 
A 1 156 GLN 156 156 156 GLN GLN A . n 
A 1 157 GLN 157 157 157 GLN GLN A . n 
A 1 158 ILE 158 158 158 ILE ILE A . n 
A 1 159 ILE 159 159 159 ILE ILE A . n 
A 1 160 ASN 160 160 160 ASN ASN A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 GLU 162 162 162 GLU GLU A . n 
A 1 163 ALA 163 163 163 ALA ALA A . n 
A 1 164 GLU 164 164 164 GLU GLU A . n 
A 1 165 VAL 165 165 165 VAL VAL A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 ALA 167 167 167 ALA ALA A . n 
A 1 168 THR 168 168 ?   ?   ?   A . n 
A 1 169 GLN 169 169 ?   ?   ?   A . n 
A 1 170 MET 170 170 ?   ?   ?   A . n 
A 1 171 THR 171 171 ?   ?   ?   A . n 
A 1 172 TYR 172 172 ?   ?   ?   A . n 
A 1 173 PHE 173 173 ?   ?   ?   A . n 
A 1 174 ASN 174 174 ?   ?   ?   A . n 
A 1 175 GLY 175 175 ?   ?   ?   A . n 
A 1 176 SER 176 176 ?   ?   ?   A . n 
A 1 177 THR 177 177 ?   ?   ?   A . n 
A 1 178 ASN 178 178 ?   ?   ?   A . n 
A 1 179 HIS 179 179 ?   ?   ?   A . n 
A 1 180 GLY 180 180 ?   ?   ?   A . n 
A 1 181 LEU 181 181 ?   ?   ?   A . n 
A 1 182 GLU 182 182 ?   ?   ?   A . n 
A 1 183 ILE 183 183 ?   ?   ?   A . n 
A 1 184 ASP 184 184 ?   ?   ?   A . n 
A 1 185 GLU 185 185 ?   ?   ?   A . n 
A 1 186 SER 186 186 ?   ?   ?   A . n 
A 1 187 VAL 187 187 ?   ?   ?   A . n 
A 1 188 ASN 188 188 ?   ?   ?   A . n 
A 1 189 GLY 189 189 ?   ?   ?   A . n 
A 1 190 HIS 190 190 ?   ?   ?   A . n 
A 1 191 GLU 191 191 ?   ?   ?   A . n 
A 1 192 ILE 192 192 ?   ?   ?   A . n 
A 1 193 ASN 193 193 ?   ?   ?   A . n 
A 1 194 GLU 194 194 ?   ?   ?   A . n 
A 1 195 ARG 195 195 ?   ?   ?   A . n 
A 1 196 LYS 196 196 ?   ?   ?   A . n 
A 1 197 GLU 197 197 ?   ?   ?   A . n 
A 1 198 LYS 198 198 ?   ?   ?   A . n 
A 1 199 THR 199 199 ?   ?   ?   A . n 
A 1 200 LYS 200 200 ?   ?   ?   A . n 
A 1 201 PRO 201 201 ?   ?   ?   A . n 
A 1 202 VAL 202 202 ?   ?   ?   A . n 
A 1 203 PRO 203 203 ?   ?   ?   A . n 
A 1 204 GLY 204 204 ?   ?   ?   A . n 
A 1 205 TYR 205 205 ?   ?   ?   A . n 
A 1 206 ASN 206 206 ?   ?   ?   A . n 
A 1 207 ASN 207 207 ?   ?   ?   A . n 
A 1 208 ASP 208 208 ?   ?   ?   A . n 
A 1 209 THR 209 209 ?   ?   ?   A . n 
A 1 210 GLY 210 210 ?   ?   ?   A . n 
A 1 211 LYS 211 211 ?   ?   ?   A . n 
A 1 212 ILE 212 212 ?   ?   ?   A . n 
A 1 213 SER 213 213 ?   ?   ?   A . n 
A 1 214 SER 214 214 ?   ?   ?   A . n 
A 1 215 LYS 215 215 ?   ?   ?   A . n 
A 1 216 VAL 216 216 ?   ?   ?   A . n 
A 1 217 GLU 217 217 ?   ?   ?   A . n 
A 1 218 LEU 218 218 ?   ?   ?   A . n 
A 1 219 GLU 219 219 ?   ?   ?   A . n 
A 1 220 LYS 220 220 ?   ?   ?   A . n 
A 1 221 ASN 221 221 ?   ?   ?   A . n 
A 1 222 SER 222 222 ?   ?   ?   A . n 
A 1 223 GLY 223 223 ?   ?   ?   A . n 
A 1 224 MET 224 224 ?   ?   ?   A . n 
A 1 225 ARG 225 225 ?   ?   ?   A . n 
A 1 226 THR 226 226 ?   ?   ?   A . n 
A 1 227 LYS 227 227 ?   ?   ?   A . n 
A 1 228 TYR 228 228 ?   ?   ?   A . n 
A 1 229 ARG 229 229 ?   ?   ?   A . n 
A 1 230 THR 230 230 230 THR THR A . n 
A 1 231 LYS 231 231 231 LYS LYS A . n 
A 1 232 LYS 232 232 232 LYS LYS A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 HIS 234 234 234 HIS HIS A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 THR 236 236 236 THR THR A . n 
A 1 237 ARG 237 237 237 ARG ARG A . n 
A 1 238 LYS 238 238 238 LYS LYS A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 THR 240 240 240 THR THR A . n 
A 1 241 CYS 241 241 241 CYS CYS A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 CYS 243 243 243 CYS CYS A . n 
A 1 244 ILE 244 244 244 ILE ILE A . n 
A 1 245 ALA 245 245 245 ALA ALA A . n 
A 1 246 TYR 246 246 246 TYR TYR A . n 
A 1 247 SER 247 247 247 SER SER A . n 
A 1 248 SER 248 248 248 SER SER A . n 
A 1 249 THR 249 249 249 THR THR A . n 
A 1 250 ILE 250 250 250 ILE ILE A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 GLY 252 252 252 GLY GLY A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 THR 254 254 254 THR THR A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLY 258 258 258 GLY GLY A . n 
A 1 259 THR 259 259 259 THR THR A . n 
A 1 260 SER 260 260 260 SER SER A . n 
A 1 261 THR 261 261 261 THR THR A . n 
A 1 262 ASN 262 262 262 ASN ASN A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 ILE 264 264 264 ILE ILE A . n 
A 1 265 PHE 265 265 265 PHE PHE A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 GLU 267 267 267 GLU GLU A . n 
A 1 268 TYR 268 268 268 TYR TYR A . n 
A 1 269 PHE 269 269 269 PHE PHE A . n 
A 1 270 ASN 270 270 270 ASN ASN A . n 
A 1 271 THR 271 271 271 THR THR A . n 
A 1 272 ARG 272 272 272 ARG ARG A . n 
A 1 273 TYR 273 273 273 TYR TYR A . n 
A 1 274 PRO 274 274 274 PRO PRO A . n 
A 1 275 ASP 275 275 275 ASP ASP A . n 
A 1 276 CYS 276 276 276 CYS CYS A . n 
A 1 277 ARG 277 277 277 ARG ARG A . n 
A 1 278 CYS 278 278 278 CYS CYS A . n 
A 1 279 LEU 279 279 279 LEU LEU A . n 
A 1 280 ASN 280 280 280 ASN ASN A . n 
A 1 281 PHE 281 281 281 PHE PHE A . n 
A 1 282 GLY 282 282 282 GLY GLY A . n 
A 1 283 SER 283 283 283 SER SER A . n 
A 1 284 TRP 284 284 284 TRP TRP A . n 
A 1 285 PHE 285 285 285 PHE PHE A . n 
A 1 286 THR 286 286 286 THR THR A . n 
A 1 287 PHE 287 287 287 PHE PHE A . n 
A 1 288 SER 288 288 288 SER SER A . n 
A 1 289 PHE 289 289 289 PHE PHE A . n 
A 1 290 PRO 290 290 290 PRO PRO A . n 
A 1 291 ALA 291 291 291 ALA ALA A . n 
A 1 292 ALA 292 292 292 ALA ALA A . n 
A 1 293 LEU 293 293 293 LEU LEU A . n 
A 1 294 ILE 294 294 294 ILE ILE A . n 
A 1 295 ILE 295 295 295 ILE ILE A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 LEU 298 298 298 LEU LEU A . n 
A 1 299 SER 299 299 299 SER SER A . n 
A 1 300 TRP 300 300 300 TRP TRP A . n 
A 1 301 ILE 301 301 301 ILE ILE A . n 
A 1 302 TRP 302 302 302 TRP TRP A . n 
A 1 303 LEU 303 303 303 LEU LEU A . n 
A 1 304 GLN 304 304 304 GLN GLN A . n 
A 1 305 TRP 305 305 305 TRP TRP A . n 
A 1 306 LEU 306 306 306 LEU LEU A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 LEU 308 308 308 LEU LEU A . n 
A 1 309 GLY 309 309 309 GLY GLY A . n 
A 1 310 PHE 310 310 310 PHE PHE A . n 
A 1 311 ASN 311 311 311 ASN ASN A . n 
A 1 312 PHE 312 312 312 PHE PHE A . n 
A 1 313 LYS 313 313 313 LYS LYS A . n 
A 1 314 GLU 314 314 314 GLU GLU A . n 
A 1 315 MET 315 315 315 MET MET A . n 
A 1 316 PHE 316 316 316 PHE PHE A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 CYS 318 318 ?   ?   ?   A . n 
A 1 319 GLY 319 319 ?   ?   ?   A . n 
A 1 320 LYS 320 320 ?   ?   ?   A . n 
A 1 321 THR 321 321 ?   ?   ?   A . n 
A 1 322 LYS 322 322 322 LYS LYS A . n 
A 1 323 THR 323 323 323 THR THR A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 GLN 325 325 325 GLN GLN A . n 
A 1 326 GLN 326 326 326 GLN GLN A . n 
A 1 327 LYS 327 327 327 LYS LYS A . n 
A 1 328 ALA 328 328 328 ALA ALA A . n 
A 1 329 CYS 329 329 329 CYS CYS A . n 
A 1 330 ALA 330 330 330 ALA ALA A . n 
A 1 331 GLU 331 331 331 GLU GLU A . n 
A 1 332 VAL 332 332 332 VAL VAL A . n 
A 1 333 ILE 333 333 333 ILE ILE A . n 
A 1 334 LYS 334 334 334 LYS LYS A . n 
A 1 335 GLN 335 335 335 GLN GLN A . n 
A 1 336 GLU 336 336 336 GLU GLU A . n 
A 1 337 TYR 337 337 337 TYR TYR A . n 
A 1 338 GLN 338 338 338 GLN GLN A . n 
A 1 339 LYS 339 339 339 LYS LYS A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 GLY 341 341 341 GLY GLY A . n 
A 1 342 PRO 342 342 342 PRO PRO A . n 
A 1 343 ILE 343 343 343 ILE ILE A . n 
A 1 344 ARG 344 344 344 ARG ARG A . n 
A 1 345 TYR 345 345 345 TYR TYR A . n 
A 1 346 GLN 346 346 346 GLN GLN A . n 
A 1 347 GLU 347 347 347 GLU GLU A . n 
A 1 348 ILE 348 348 348 ILE ILE A . n 
A 1 349 VAL 349 349 349 VAL VAL A . n 
A 1 350 THR 350 350 350 THR THR A . n 
A 1 351 LEU 351 351 351 LEU LEU A . n 
A 1 352 VAL 352 352 352 VAL VAL A . n 
A 1 353 LEU 353 353 353 LEU LEU A . n 
A 1 354 PHE 354 354 354 PHE PHE A . n 
A 1 355 ILE 355 355 355 ILE ILE A . n 
A 1 356 ILE 356 356 356 ILE ILE A . n 
A 1 357 MET 357 357 357 MET MET A . n 
A 1 358 ALA 358 358 358 ALA ALA A . n 
A 1 359 LEU 359 359 359 LEU LEU A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 TRP 361 361 361 TRP TRP A . n 
A 1 362 PHE 362 362 362 PHE PHE A . n 
A 1 363 SER 363 363 363 SER SER A . n 
A 1 364 ARG 364 364 364 ARG ARG A . n 
A 1 365 ASP 365 365 365 ASP ASP A . n 
A 1 366 PRO 366 366 366 PRO PRO A . n 
A 1 367 GLY 367 367 ?   ?   ?   A . n 
A 1 368 PHE 368 368 ?   ?   ?   A . n 
A 1 369 VAL 369 369 ?   ?   ?   A . n 
A 1 370 PRO 370 370 ?   ?   ?   A . n 
A 1 371 GLY 371 371 ?   ?   ?   A . n 
A 1 372 TRP 372 372 ?   ?   ?   A . n 
A 1 373 SER 373 373 373 SER SER A . n 
A 1 374 ALA 374 374 374 ALA ALA A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 PHE 376 376 376 PHE PHE A . n 
A 1 377 SER 377 377 377 SER SER A . n 
A 1 378 GLU 378 378 378 GLU GLU A . n 
A 1 379 TYR 379 379 379 TYR TYR A . n 
A 1 380 PRO 380 380 380 PRO PRO A . n 
A 1 381 GLY 381 381 381 GLY GLY A . n 
A 1 382 PHE 382 382 382 PHE PHE A . n 
A 1 383 ALA 383 383 383 ALA ALA A . n 
A 1 384 THR 384 384 384 THR THR A . n 
A 1 385 ASP 385 385 385 ASP ASP A . n 
A 1 386 SER 386 386 386 SER SER A . n 
A 1 387 THR 387 387 387 THR THR A . n 
A 1 388 VAL 388 388 388 VAL VAL A . n 
A 1 389 ALA 389 389 389 ALA ALA A . n 
A 1 390 LEU 390 390 390 LEU LEU A . n 
A 1 391 LEU 391 391 391 LEU LEU A . n 
A 1 392 ILE 392 392 392 ILE ILE A . n 
A 1 393 GLY 393 393 393 GLY GLY A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 LEU 395 395 395 LEU LEU A . n 
A 1 396 PHE 396 396 396 PHE PHE A . n 
A 1 397 PHE 397 397 397 PHE PHE A . n 
A 1 398 LEU 398 398 398 LEU LEU A . n 
A 1 399 ILE 399 399 399 ILE ILE A . n 
A 1 400 PRO 400 400 400 PRO PRO A . n 
A 1 401 ALA 401 401 401 ALA ALA A . n 
A 1 402 LYS 402 402 402 LYS LYS A . n 
A 1 403 THR 403 403 403 THR THR A . n 
A 1 404 LEU 404 404 404 LEU LEU A . n 
A 1 405 THR 405 405 ?   ?   ?   A . n 
A 1 406 LYS 406 406 ?   ?   ?   A . n 
A 1 407 THR 407 407 ?   ?   ?   A . n 
A 1 408 THR 408 408 ?   ?   ?   A . n 
A 1 409 PRO 409 409 ?   ?   ?   A . n 
A 1 410 THR 410 410 ?   ?   ?   A . n 
A 1 411 GLY 411 411 ?   ?   ?   A . n 
A 1 412 GLU 412 412 ?   ?   ?   A . n 
A 1 413 ILE 413 413 ?   ?   ?   A . n 
A 1 414 VAL 414 414 ?   ?   ?   A . n 
A 1 415 ALA 415 415 415 ALA ALA A . n 
A 1 416 PHE 416 416 416 PHE PHE A . n 
A 1 417 ASP 417 417 417 ASP ASP A . n 
A 1 418 TYR 418 418 418 TYR TYR A . n 
A 1 419 SER 419 419 419 SER SER A . n 
A 1 420 PRO 420 420 420 PRO PRO A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 ILE 422 422 422 ILE ILE A . n 
A 1 423 THR 423 423 423 THR THR A . n 
A 1 424 TRP 424 424 424 TRP TRP A . n 
A 1 425 LYS 425 425 425 LYS LYS A . n 
A 1 426 GLU 426 426 426 GLU GLU A . n 
A 1 427 PHE 427 427 427 PHE PHE A . n 
A 1 428 GLN 428 428 428 GLN GLN A . n 
A 1 429 SER 429 429 429 SER SER A . n 
A 1 430 PHE 430 430 430 PHE PHE A . n 
A 1 431 MET 431 431 431 MET MET A . n 
A 1 432 PRO 432 432 432 PRO PRO A . n 
A 1 433 TRP 433 433 433 TRP TRP A . n 
A 1 434 ASP 434 434 434 ASP ASP A . n 
A 1 435 ILE 435 435 435 ILE ILE A . n 
A 1 436 ALA 436 436 436 ALA ALA A . n 
A 1 437 ILE 437 437 437 ILE ILE A . n 
A 1 438 LEU 438 438 438 LEU LEU A . n 
A 1 439 VAL 439 439 439 VAL VAL A . n 
A 1 440 GLY 440 440 440 GLY GLY A . n 
A 1 441 GLY 441 441 441 GLY GLY A . n 
A 1 442 GLY 442 442 442 GLY GLY A . n 
A 1 443 PHE 443 443 443 PHE PHE A . n 
A 1 444 ALA 444 444 444 ALA ALA A . n 
A 1 445 LEU 445 445 445 LEU LEU A . n 
A 1 446 ALA 446 446 446 ALA ALA A . n 
A 1 447 ASP 447 447 447 ASP ASP A . n 
A 1 448 GLY 448 448 448 GLY GLY A . n 
A 1 449 CYS 449 449 449 CYS CYS A . n 
A 1 450 GLU 450 450 450 GLU GLU A . n 
A 1 451 GLU 451 451 451 GLU GLU A . n 
A 1 452 SER 452 452 452 SER SER A . n 
A 1 453 GLY 453 453 453 GLY GLY A . n 
A 1 454 LEU 454 454 454 LEU LEU A . n 
A 1 455 SER 455 455 455 SER SER A . n 
A 1 456 LYS 456 456 456 LYS LYS A . n 
A 1 457 TRP 457 457 457 TRP TRP A . n 
A 1 458 ILE 458 458 458 ILE ILE A . n 
A 1 459 GLY 459 459 459 GLY GLY A . n 
A 1 460 ASN 460 460 460 ASN ASN A . n 
A 1 461 LYS 461 461 461 LYS LYS A . n 
A 1 462 LEU 462 462 462 LEU LEU A . n 
A 1 463 SER 463 463 463 SER SER A . n 
A 1 464 PRO 464 464 464 PRO PRO A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 GLY 466 466 466 GLY GLY A . n 
A 1 467 SER 467 467 467 SER SER A . n 
A 1 468 LEU 468 468 468 LEU LEU A . n 
A 1 469 PRO 469 469 469 PRO PRO A . n 
A 1 470 ALA 470 470 470 ALA ALA A . n 
A 1 471 TRP 471 471 471 TRP TRP A . n 
A 1 472 LEU 472 472 472 LEU LEU A . n 
A 1 473 ILE 473 473 473 ILE ILE A . n 
A 1 474 ILE 474 474 474 ILE ILE A . n 
A 1 475 LEU 475 475 475 LEU LEU A . n 
A 1 476 ILE 476 476 476 ILE ILE A . n 
A 1 477 SER 477 477 477 SER SER A . n 
A 1 478 SER 478 478 478 SER SER A . n 
A 1 479 LEU 479 479 479 LEU LEU A . n 
A 1 480 MET 480 480 480 MET MET A . n 
A 1 481 VAL 481 481 481 VAL VAL A . n 
A 1 482 THR 482 482 482 THR THR A . n 
A 1 483 SER 483 483 483 SER SER A . n 
A 1 484 LEU 484 484 484 LEU LEU A . n 
A 1 485 THR 485 485 485 THR THR A . n 
A 1 486 GLU 486 486 486 GLU GLU A . n 
A 1 487 VAL 487 487 487 VAL VAL A . n 
A 1 488 ALA 488 488 488 ALA ALA A . n 
A 1 489 SER 489 489 489 SER SER A . n 
A 1 490 ASN 490 490 490 ASN ASN A . n 
A 1 491 PRO 491 491 491 PRO PRO A . n 
A 1 492 ALA 492 492 492 ALA ALA A . n 
A 1 493 THR 493 493 493 THR THR A . n 
A 1 494 ILE 494 494 494 ILE ILE A . n 
A 1 495 THR 495 495 495 THR THR A . n 
A 1 496 LEU 496 496 496 LEU LEU A . n 
A 1 497 PHE 497 497 497 PHE PHE A . n 
A 1 498 LEU 498 498 498 LEU LEU A . n 
A 1 499 PRO 499 499 499 PRO PRO A . n 
A 1 500 ILE 500 500 500 ILE ILE A . n 
A 1 501 LEU 501 501 501 LEU LEU A . n 
A 1 502 SER 502 502 502 SER SER A . n 
A 1 503 PRO 503 503 503 PRO PRO A . n 
A 1 504 LEU 504 504 504 LEU LEU A . n 
A 1 505 ALA 505 505 505 ALA ALA A . n 
A 1 506 GLU 506 506 506 GLU GLU A . n 
A 1 507 ALA 507 507 507 ALA ALA A . n 
A 1 508 ILE 508 508 508 ILE ILE A . n 
A 1 509 HIS 509 509 509 HIS HIS A . n 
A 1 510 VAL 510 510 510 VAL VAL A . n 
A 1 511 ASN 511 511 511 ASN ASN A . n 
A 1 512 PRO 512 512 512 PRO PRO A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 TYR 514 514 514 TYR TYR A . n 
A 1 515 ILE 515 515 515 ILE ILE A . n 
A 1 516 LEU 516 516 516 LEU LEU A . n 
A 1 517 ILE 517 517 517 ILE ILE A . n 
A 1 518 PRO 518 518 518 PRO PRO A . n 
A 1 519 SER 519 519 519 SER SER A . n 
A 1 520 THR 520 520 520 THR THR A . n 
A 1 521 LEU 521 521 521 LEU LEU A . n 
A 1 522 CYS 522 522 522 CYS CYS A . n 
A 1 523 THR 523 523 523 THR THR A . n 
A 1 524 SER 524 524 524 SER SER A . n 
A 1 525 PHE 525 525 525 PHE PHE A . n 
A 1 526 ALA 526 526 526 ALA ALA A . n 
A 1 527 PHE 527 527 527 PHE PHE A . n 
A 1 528 LEU 528 528 528 LEU LEU A . n 
A 1 529 LEU 529 529 529 LEU LEU A . n 
A 1 530 PRO 530 530 530 PRO PRO A . n 
A 1 531 VAL 531 531 531 VAL VAL A . n 
A 1 532 ALA 532 532 532 ALA ALA A . n 
A 1 533 ASN 533 533 533 ASN ASN A . n 
A 1 534 PRO 534 534 534 PRO PRO A . n 
A 1 535 PRO 535 535 535 PRO PRO A . n 
A 1 536 ASN 536 536 536 ASN ASN A . n 
A 1 537 ALA 537 537 537 ALA ALA A . n 
A 1 538 ILE 538 538 538 ILE ILE A . n 
A 1 539 VAL 539 539 539 VAL VAL A . n 
A 1 540 PHE 540 540 540 PHE PHE A . n 
A 1 541 SER 541 541 541 SER SER A . n 
A 1 542 TYR 542 542 542 TYR TYR A . n 
A 1 543 GLY 543 543 543 GLY GLY A . n 
A 1 544 HIS 544 544 544 HIS HIS A . n 
A 1 545 LEU 545 545 545 LEU LEU A . n 
A 1 546 LYS 546 546 546 LYS LYS A . n 
A 1 547 VAL 547 547 547 VAL VAL A . n 
A 1 548 ILE 548 548 548 ILE ILE A . n 
A 1 549 ASP 549 549 549 ASP ASP A . n 
A 1 550 MET 550 550 550 MET MET A . n 
A 1 551 VAL 551 551 551 VAL VAL A . n 
A 1 552 LYS 552 552 552 LYS LYS A . n 
A 1 553 ALA 553 553 553 ALA ALA A . n 
A 1 554 GLY 554 554 554 GLY GLY A . n 
A 1 555 LEU 555 555 555 LEU LEU A . n 
A 1 556 GLY 556 556 556 GLY GLY A . n 
A 1 557 VAL 557 557 557 VAL VAL A . n 
A 1 558 ASN 558 558 558 ASN ASN A . n 
A 1 559 ILE 559 559 559 ILE ILE A . n 
A 1 560 VAL 560 560 560 VAL VAL A . n 
A 1 561 GLY 561 561 561 GLY GLY A . n 
A 1 562 VAL 562 562 562 VAL VAL A . n 
A 1 563 ALA 563 563 563 ALA ALA A . n 
A 1 564 VAL 564 564 564 VAL VAL A . n 
A 1 565 VAL 565 565 565 VAL VAL A . n 
A 1 566 MET 566 566 566 MET MET A . n 
A 1 567 LEU 567 567 567 LEU LEU A . n 
A 1 568 GLY 568 568 568 GLY GLY A . n 
A 1 569 ILE 569 569 569 ILE ILE A . n 
A 1 570 CYS 570 570 570 CYS CYS A . n 
A 1 571 THR 571 571 571 THR THR A . n 
A 1 572 TRP 572 572 572 TRP TRP A . n 
A 1 573 ILE 573 573 573 ILE ILE A . n 
A 1 574 VAL 574 574 574 VAL VAL A . n 
A 1 575 PRO 575 575 575 PRO PRO A . n 
A 1 576 MET 576 576 576 MET MET A . n 
A 1 577 PHE 577 577 577 PHE PHE A . n 
A 1 578 ASP 578 578 578 ASP ASP A . n 
A 1 579 LEU 579 579 579 LEU LEU A . n 
A 1 580 TYR 580 580 580 TYR TYR A . n 
A 1 581 THR 581 581 581 THR THR A . n 
A 1 582 TYR 582 582 582 TYR TYR A . n 
A 1 583 PRO 583 583 583 PRO PRO A . n 
A 1 584 SER 584 584 584 SER SER A . n 
A 1 585 TRP 585 585 585 TRP TRP A . n 
A 1 586 ALA 586 586 586 ALA ALA A . n 
A 1 587 PRO 587 587 587 PRO PRO A . n 
A 1 588 ALA 588 588 588 ALA ALA A . n 
A 1 589 MET 589 589 ?   ?   ?   A . n 
A 1 590 SER 590 590 ?   ?   ?   A . n 
A 1 591 ASN 591 591 ?   ?   ?   A . n 
A 1 592 GLU 592 592 ?   ?   ?   A . n 
A 1 593 THR 593 593 ?   ?   ?   A . n 
A 1 594 MET 594 594 ?   ?   ?   A . n 
A 1 595 PRO 595 595 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   LYS 2   2   2   LYS LYS B . n 
B 1 3   PHE 3   3   3   PHE PHE B . n 
B 1 4   PHE 4   4   4   PHE PHE B . n 
B 1 5   SER 5   5   5   SER SER B . n 
B 1 6   TYR 6   6   6   TYR TYR B . n 
B 1 7   ILE 7   7   7   ILE ILE B . n 
B 1 8   LEU 8   8   8   LEU LEU B . n 
B 1 9   VAL 9   9   9   VAL VAL B . n 
B 1 10  TYR 10  10  10  TYR TYR B . n 
B 1 11  ARG 11  11  11  ARG ARG B . n 
B 1 12  ARG 12  12  12  ARG ARG B . n 
B 1 13  PHE 13  13  13  PHE PHE B . n 
B 1 14  LEU 14  14  14  LEU LEU B . n 
B 1 15  PHE 15  15  15  PHE PHE B . n 
B 1 16  VAL 16  16  16  VAL VAL B . n 
B 1 17  VAL 17  17  17  VAL VAL B . n 
B 1 18  PHE 18  18  18  PHE PHE B . n 
B 1 19  THR 19  19  19  THR THR B . n 
B 1 20  VAL 20  20  20  VAL VAL B . n 
B 1 21  LEU 21  21  21  LEU LEU B . n 
B 1 22  VAL 22  22  22  VAL VAL B . n 
B 1 23  LEU 23  23  23  LEU LEU B . n 
B 1 24  LEU 24  24  24  LEU LEU B . n 
B 1 25  PRO 25  25  25  PRO PRO B . n 
B 1 26  LEU 26  26  26  LEU LEU B . n 
B 1 27  PRO 27  27  27  PRO PRO B . n 
B 1 28  ILE 28  28  28  ILE ILE B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  LEU 30  30  30  LEU LEU B . n 
B 1 31  HIS 31  31  31  HIS HIS B . n 
B 1 32  THR 32  32  32  THR THR B . n 
B 1 33  LYS 33  33  33  LYS LYS B . n 
B 1 34  GLU 34  34  34  GLU GLU B . n 
B 1 35  ALA 35  35  35  ALA ALA B . n 
B 1 36  GLU 36  36  36  GLU GLU B . n 
B 1 37  CYS 37  37  37  CYS CYS B . n 
B 1 38  ALA 38  38  38  ALA ALA B . n 
B 1 39  TYR 39  39  39  TYR TYR B . n 
B 1 40  THR 40  40  40  THR THR B . n 
B 1 41  LEU 41  41  41  LEU LEU B . n 
B 1 42  PHE 42  42  42  PHE PHE B . n 
B 1 43  VAL 43  43  43  VAL VAL B . n 
B 1 44  VAL 44  44  44  VAL VAL B . n 
B 1 45  ALA 45  45  45  ALA ALA B . n 
B 1 46  THR 46  46  46  THR THR B . n 
B 1 47  PHE 47  47  47  PHE PHE B . n 
B 1 48  TRP 48  48  48  TRP TRP B . n 
B 1 49  LEU 49  49  49  LEU LEU B . n 
B 1 50  THR 50  50  50  THR THR B . n 
B 1 51  GLU 51  51  51  GLU GLU B . n 
B 1 52  ALA 52  52  52  ALA ALA B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  PRO 54  54  54  PRO PRO B . n 
B 1 55  LEU 55  55  55  LEU LEU B . n 
B 1 56  SER 56  56  56  SER SER B . n 
B 1 57  VAL 57  57  57  VAL VAL B . n 
B 1 58  THR 58  58  58  THR THR B . n 
B 1 59  ALA 59  59  59  ALA ALA B . n 
B 1 60  LEU 60  60  60  LEU LEU B . n 
B 1 61  LEU 61  61  61  LEU LEU B . n 
B 1 62  PRO 62  62  62  PRO PRO B . n 
B 1 63  SER 63  63  63  SER SER B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  MET 65  65  65  MET MET B . n 
B 1 66  LEU 66  66  66  LEU LEU B . n 
B 1 67  PRO 67  67  67  PRO PRO B . n 
B 1 68  MET 68  68  68  MET MET B . n 
B 1 69  PHE 69  69  69  PHE PHE B . n 
B 1 70  GLY 70  70  70  GLY GLY B . n 
B 1 71  ILE 71  71  71  ILE ILE B . n 
B 1 72  MET 72  72  72  MET MET B . n 
B 1 73  PRO 73  73  73  PRO PRO B . n 
B 1 74  SER 74  74  74  SER SER B . n 
B 1 75  LYS 75  75  75  LYS LYS B . n 
B 1 76  LYS 76  76  76  LYS LYS B . n 
B 1 77  VAL 77  77  77  VAL VAL B . n 
B 1 78  ALA 78  78  78  ALA ALA B . n 
B 1 79  SER 79  79  79  SER SER B . n 
B 1 80  ALA 80  80  80  ALA ALA B . n 
B 1 81  TYR 81  81  81  TYR TYR B . n 
B 1 82  PHE 82  82  82  PHE PHE B . n 
B 1 83  LYS 83  83  83  LYS LYS B . n 
B 1 84  ASP 84  84  84  ASP ASP B . n 
B 1 85  PHE 85  85  85  PHE PHE B . n 
B 1 86  HIS 86  86  86  HIS HIS B . n 
B 1 87  LEU 87  87  87  LEU LEU B . n 
B 1 88  LEU 88  88  88  LEU LEU B . n 
B 1 89  LEU 89  89  89  LEU LEU B . n 
B 1 90  ILE 90  90  90  ILE ILE B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  VAL 92  92  92  VAL VAL B . n 
B 1 93  ILE 93  93  93  ILE ILE B . n 
B 1 94  CYS 94  94  94  CYS CYS B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  ALA 96  96  96  ALA ALA B . n 
B 1 97  THR 97  97  97  THR THR B . n 
B 1 98  SER 98  98  98  SER SER B . n 
B 1 99  ILE 99  99  99  ILE ILE B . n 
B 1 100 GLU 100 100 100 GLU GLU B . n 
B 1 101 LYS 101 101 101 LYS LYS B . n 
B 1 102 TRP 102 102 102 TRP TRP B . n 
B 1 103 ASN 103 103 103 ASN ASN B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 HIS 105 105 105 HIS HIS B . n 
B 1 106 LYS 106 106 106 LYS LYS B . n 
B 1 107 ARG 107 107 107 ARG ARG B . n 
B 1 108 ILE 108 108 108 ILE ILE B . n 
B 1 109 ALA 109 109 109 ALA ALA B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 LYS 111 111 111 LYS LYS B . n 
B 1 112 MET 112 112 112 MET MET B . n 
B 1 113 VAL 113 113 113 VAL VAL B . n 
B 1 114 MET 114 114 114 MET MET B . n 
B 1 115 MET 115 115 115 MET MET B . n 
B 1 116 VAL 116 116 116 VAL VAL B . n 
B 1 117 GLY 117 117 117 GLY GLY B . n 
B 1 118 VAL 118 118 118 VAL VAL B . n 
B 1 119 ASN 119 119 119 ASN ASN B . n 
B 1 120 PRO 120 120 120 PRO PRO B . n 
B 1 121 ALA 121 121 121 ALA ALA B . n 
B 1 122 TRP 122 122 122 TRP TRP B . n 
B 1 123 LEU 123 123 123 LEU LEU B . n 
B 1 124 THR 124 124 124 THR THR B . n 
B 1 125 LEU 125 125 125 LEU LEU B . n 
B 1 126 GLY 126 126 126 GLY GLY B . n 
B 1 127 PHE 127 127 127 PHE PHE B . n 
B 1 128 MET 128 128 128 MET MET B . n 
B 1 129 SER 129 129 129 SER SER B . n 
B 1 130 SER 130 130 130 SER SER B . n 
B 1 131 THR 131 131 131 THR THR B . n 
B 1 132 ALA 132 132 132 ALA ALA B . n 
B 1 133 PHE 133 133 133 PHE PHE B . n 
B 1 134 LEU 134 134 134 LEU LEU B . n 
B 1 135 SER 135 135 135 SER SER B . n 
B 1 136 MET 136 136 136 MET MET B . n 
B 1 137 TRP 137 137 137 TRP TRP B . n 
B 1 138 LEU 138 138 138 LEU LEU B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 ASN 140 140 140 ASN ASN B . n 
B 1 141 THR 141 141 141 THR THR B . n 
B 1 142 SER 142 142 142 SER SER B . n 
B 1 143 THR 143 143 143 THR THR B . n 
B 1 144 ALA 144 144 144 ALA ALA B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 MET 146 146 146 MET MET B . n 
B 1 147 VAL 147 147 147 VAL VAL B . n 
B 1 148 MET 148 148 148 MET MET B . n 
B 1 149 PRO 149 149 149 PRO PRO B . n 
B 1 150 ILE 150 150 150 ILE ILE B . n 
B 1 151 ALA 151 151 151 ALA ALA B . n 
B 1 152 GLU 152 152 152 GLU GLU B . n 
B 1 153 ALA 153 153 153 ALA ALA B . n 
B 1 154 VAL 154 154 154 VAL VAL B . n 
B 1 155 VAL 155 155 155 VAL VAL B . n 
B 1 156 GLN 156 156 156 GLN GLN B . n 
B 1 157 GLN 157 157 157 GLN GLN B . n 
B 1 158 ILE 158 158 158 ILE ILE B . n 
B 1 159 ILE 159 159 159 ILE ILE B . n 
B 1 160 ASN 160 160 160 ASN ASN B . n 
B 1 161 ALA 161 161 161 ALA ALA B . n 
B 1 162 GLU 162 162 162 GLU ALA B . n 
B 1 163 ALA 163 163 163 ALA ALA B . n 
B 1 164 GLU 164 164 164 GLU ALA B . n 
B 1 165 VAL 165 165 165 VAL ALA B . n 
B 1 166 GLU 166 166 166 GLU ALA B . n 
B 1 167 ALA 167 167 ?   ?   ?   B . n 
B 1 168 THR 168 168 ?   ?   ?   B . n 
B 1 169 GLN 169 169 ?   ?   ?   B . n 
B 1 170 MET 170 170 ?   ?   ?   B . n 
B 1 171 THR 171 171 ?   ?   ?   B . n 
B 1 172 TYR 172 172 ?   ?   ?   B . n 
B 1 173 PHE 173 173 ?   ?   ?   B . n 
B 1 174 ASN 174 174 ?   ?   ?   B . n 
B 1 175 GLY 175 175 ?   ?   ?   B . n 
B 1 176 SER 176 176 ?   ?   ?   B . n 
B 1 177 THR 177 177 ?   ?   ?   B . n 
B 1 178 ASN 178 178 ?   ?   ?   B . n 
B 1 179 HIS 179 179 ?   ?   ?   B . n 
B 1 180 GLY 180 180 ?   ?   ?   B . n 
B 1 181 LEU 181 181 ?   ?   ?   B . n 
B 1 182 GLU 182 182 ?   ?   ?   B . n 
B 1 183 ILE 183 183 ?   ?   ?   B . n 
B 1 184 ASP 184 184 ?   ?   ?   B . n 
B 1 185 GLU 185 185 ?   ?   ?   B . n 
B 1 186 SER 186 186 ?   ?   ?   B . n 
B 1 187 VAL 187 187 ?   ?   ?   B . n 
B 1 188 ASN 188 188 ?   ?   ?   B . n 
B 1 189 GLY 189 189 ?   ?   ?   B . n 
B 1 190 HIS 190 190 ?   ?   ?   B . n 
B 1 191 GLU 191 191 ?   ?   ?   B . n 
B 1 192 ILE 192 192 ?   ?   ?   B . n 
B 1 193 ASN 193 193 ?   ?   ?   B . n 
B 1 194 GLU 194 194 ?   ?   ?   B . n 
B 1 195 ARG 195 195 ?   ?   ?   B . n 
B 1 196 LYS 196 196 ?   ?   ?   B . n 
B 1 197 GLU 197 197 ?   ?   ?   B . n 
B 1 198 LYS 198 198 ?   ?   ?   B . n 
B 1 199 THR 199 199 ?   ?   ?   B . n 
B 1 200 LYS 200 200 ?   ?   ?   B . n 
B 1 201 PRO 201 201 ?   ?   ?   B . n 
B 1 202 VAL 202 202 ?   ?   ?   B . n 
B 1 203 PRO 203 203 ?   ?   ?   B . n 
B 1 204 GLY 204 204 ?   ?   ?   B . n 
B 1 205 TYR 205 205 ?   ?   ?   B . n 
B 1 206 ASN 206 206 ?   ?   ?   B . n 
B 1 207 ASN 207 207 ?   ?   ?   B . n 
B 1 208 ASP 208 208 ?   ?   ?   B . n 
B 1 209 THR 209 209 ?   ?   ?   B . n 
B 1 210 GLY 210 210 ?   ?   ?   B . n 
B 1 211 LYS 211 211 ?   ?   ?   B . n 
B 1 212 ILE 212 212 ?   ?   ?   B . n 
B 1 213 SER 213 213 ?   ?   ?   B . n 
B 1 214 SER 214 214 ?   ?   ?   B . n 
B 1 215 LYS 215 215 ?   ?   ?   B . n 
B 1 216 VAL 216 216 ?   ?   ?   B . n 
B 1 217 GLU 217 217 ?   ?   ?   B . n 
B 1 218 LEU 218 218 ?   ?   ?   B . n 
B 1 219 GLU 219 219 ?   ?   ?   B . n 
B 1 220 LYS 220 220 ?   ?   ?   B . n 
B 1 221 ASN 221 221 ?   ?   ?   B . n 
B 1 222 SER 222 222 ?   ?   ?   B . n 
B 1 223 GLY 223 223 ?   ?   ?   B . n 
B 1 224 MET 224 224 ?   ?   ?   B . n 
B 1 225 ARG 225 225 ?   ?   ?   B . n 
B 1 226 THR 226 226 ?   ?   ?   B . n 
B 1 227 LYS 227 227 ?   ?   ?   B . n 
B 1 228 TYR 228 228 ?   ?   ?   B . n 
B 1 229 ARG 229 229 ?   ?   ?   B . n 
B 1 230 THR 230 230 230 THR THR B . n 
B 1 231 LYS 231 231 231 LYS LYS B . n 
B 1 232 LYS 232 232 232 LYS LYS B . n 
B 1 233 GLY 233 233 233 GLY GLY B . n 
B 1 234 HIS 234 234 234 HIS HIS B . n 
B 1 235 VAL 235 235 235 VAL VAL B . n 
B 1 236 THR 236 236 236 THR THR B . n 
B 1 237 ARG 237 237 237 ARG ARG B . n 
B 1 238 LYS 238 238 238 LYS LYS B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 THR 240 240 240 THR THR B . n 
B 1 241 CYS 241 241 241 CYS CYS B . n 
B 1 242 LEU 242 242 242 LEU LEU B . n 
B 1 243 CYS 243 243 243 CYS CYS B . n 
B 1 244 ILE 244 244 244 ILE ILE B . n 
B 1 245 ALA 245 245 245 ALA ALA B . n 
B 1 246 TYR 246 246 246 TYR TYR B . n 
B 1 247 SER 247 247 247 SER SER B . n 
B 1 248 SER 248 248 248 SER SER B . n 
B 1 249 THR 249 249 249 THR THR B . n 
B 1 250 ILE 250 250 250 ILE ILE B . n 
B 1 251 GLY 251 251 251 GLY GLY B . n 
B 1 252 GLY 252 252 252 GLY GLY B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 THR 254 254 254 THR THR B . n 
B 1 255 THR 255 255 255 THR THR B . n 
B 1 256 ILE 256 256 256 ILE ILE B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLY 258 258 258 GLY GLY B . n 
B 1 259 THR 259 259 259 THR THR B . n 
B 1 260 SER 260 260 260 SER SER B . n 
B 1 261 THR 261 261 261 THR THR B . n 
B 1 262 ASN 262 262 262 ASN ASN B . n 
B 1 263 LEU 263 263 263 LEU LEU B . n 
B 1 264 ILE 264 264 264 ILE ILE B . n 
B 1 265 PHE 265 265 265 PHE PHE B . n 
B 1 266 ALA 266 266 266 ALA ALA B . n 
B 1 267 GLU 267 267 267 GLU GLU B . n 
B 1 268 TYR 268 268 268 TYR TYR B . n 
B 1 269 PHE 269 269 269 PHE PHE B . n 
B 1 270 ASN 270 270 270 ASN ASN B . n 
B 1 271 THR 271 271 271 THR THR B . n 
B 1 272 ARG 272 272 272 ARG ARG B . n 
B 1 273 TYR 273 273 273 TYR TYR B . n 
B 1 274 PRO 274 274 274 PRO PRO B . n 
B 1 275 ASP 275 275 275 ASP ASP B . n 
B 1 276 CYS 276 276 276 CYS CYS B . n 
B 1 277 ARG 277 277 277 ARG ARG B . n 
B 1 278 CYS 278 278 278 CYS CYS B . n 
B 1 279 LEU 279 279 279 LEU LEU B . n 
B 1 280 ASN 280 280 280 ASN ASN B . n 
B 1 281 PHE 281 281 281 PHE PHE B . n 
B 1 282 GLY 282 282 282 GLY GLY B . n 
B 1 283 SER 283 283 283 SER SER B . n 
B 1 284 TRP 284 284 284 TRP TRP B . n 
B 1 285 PHE 285 285 285 PHE PHE B . n 
B 1 286 THR 286 286 286 THR THR B . n 
B 1 287 PHE 287 287 287 PHE PHE B . n 
B 1 288 SER 288 288 288 SER SER B . n 
B 1 289 PHE 289 289 289 PHE PHE B . n 
B 1 290 PRO 290 290 290 PRO PRO B . n 
B 1 291 ALA 291 291 291 ALA ALA B . n 
B 1 292 ALA 292 292 292 ALA ALA B . n 
B 1 293 LEU 293 293 293 LEU LEU B . n 
B 1 294 ILE 294 294 294 ILE ILE B . n 
B 1 295 ILE 295 295 295 ILE ILE B . n 
B 1 296 LEU 296 296 296 LEU LEU B . n 
B 1 297 LEU 297 297 297 LEU LEU B . n 
B 1 298 LEU 298 298 298 LEU LEU B . n 
B 1 299 SER 299 299 299 SER SER B . n 
B 1 300 TRP 300 300 300 TRP TRP B . n 
B 1 301 ILE 301 301 301 ILE ILE B . n 
B 1 302 TRP 302 302 302 TRP TRP B . n 
B 1 303 LEU 303 303 303 LEU LEU B . n 
B 1 304 GLN 304 304 304 GLN GLN B . n 
B 1 305 TRP 305 305 305 TRP TRP B . n 
B 1 306 LEU 306 306 306 LEU LEU B . n 
B 1 307 PHE 307 307 307 PHE PHE B . n 
B 1 308 LEU 308 308 308 LEU LEU B . n 
B 1 309 GLY 309 309 309 GLY GLY B . n 
B 1 310 PHE 310 310 310 PHE PHE B . n 
B 1 311 ASN 311 311 311 ASN ASN B . n 
B 1 312 PHE 312 312 312 PHE PHE B . n 
B 1 313 LYS 313 313 313 LYS LYS B . n 
B 1 314 GLU 314 314 314 GLU GLU B . n 
B 1 315 MET 315 315 315 MET MET B . n 
B 1 316 PHE 316 316 316 PHE PHE B . n 
B 1 317 LYS 317 317 ?   ?   ?   B . n 
B 1 318 CYS 318 318 ?   ?   ?   B . n 
B 1 319 GLY 319 319 ?   ?   ?   B . n 
B 1 320 LYS 320 320 ?   ?   ?   B . n 
B 1 321 THR 321 321 ?   ?   ?   B . n 
B 1 322 LYS 322 322 ?   ?   ?   B . n 
B 1 323 THR 323 323 323 THR THR B . n 
B 1 324 VAL 324 324 324 VAL VAL B . n 
B 1 325 GLN 325 325 325 GLN GLN B . n 
B 1 326 GLN 326 326 326 GLN GLN B . n 
B 1 327 LYS 327 327 327 LYS LYS B . n 
B 1 328 ALA 328 328 328 ALA ALA B . n 
B 1 329 CYS 329 329 329 CYS CYS B . n 
B 1 330 ALA 330 330 330 ALA ALA B . n 
B 1 331 GLU 331 331 331 GLU GLU B . n 
B 1 332 VAL 332 332 332 VAL VAL B . n 
B 1 333 ILE 333 333 333 ILE ILE B . n 
B 1 334 LYS 334 334 334 LYS LYS B . n 
B 1 335 GLN 335 335 335 GLN GLN B . n 
B 1 336 GLU 336 336 336 GLU GLU B . n 
B 1 337 TYR 337 337 337 TYR TYR B . n 
B 1 338 GLN 338 338 338 GLN GLN B . n 
B 1 339 LYS 339 339 339 LYS LYS B . n 
B 1 340 LEU 340 340 340 LEU LEU B . n 
B 1 341 GLY 341 341 341 GLY GLY B . n 
B 1 342 PRO 342 342 342 PRO PRO B . n 
B 1 343 ILE 343 343 343 ILE ILE B . n 
B 1 344 ARG 344 344 344 ARG ARG B . n 
B 1 345 TYR 345 345 345 TYR TYR B . n 
B 1 346 GLN 346 346 346 GLN GLN B . n 
B 1 347 GLU 347 347 347 GLU GLU B . n 
B 1 348 ILE 348 348 348 ILE ILE B . n 
B 1 349 VAL 349 349 349 VAL VAL B . n 
B 1 350 THR 350 350 350 THR THR B . n 
B 1 351 LEU 351 351 351 LEU LEU B . n 
B 1 352 VAL 352 352 352 VAL VAL B . n 
B 1 353 LEU 353 353 353 LEU LEU B . n 
B 1 354 PHE 354 354 354 PHE PHE B . n 
B 1 355 ILE 355 355 355 ILE ILE B . n 
B 1 356 ILE 356 356 356 ILE ILE B . n 
B 1 357 MET 357 357 357 MET MET B . n 
B 1 358 ALA 358 358 358 ALA ALA B . n 
B 1 359 LEU 359 359 359 LEU LEU B . n 
B 1 360 LEU 360 360 360 LEU LEU B . n 
B 1 361 TRP 361 361 361 TRP TRP B . n 
B 1 362 PHE 362 362 362 PHE PHE B . n 
B 1 363 SER 363 363 363 SER SER B . n 
B 1 364 ARG 364 364 364 ARG ARG B . n 
B 1 365 ASP 365 365 365 ASP ASP B . n 
B 1 366 PRO 366 366 366 PRO PRO B . n 
B 1 367 GLY 367 367 367 GLY GLY B . n 
B 1 368 PHE 368 368 368 PHE PHE B . n 
B 1 369 VAL 369 369 369 VAL VAL B . n 
B 1 370 PRO 370 370 370 PRO PRO B . n 
B 1 371 GLY 371 371 371 GLY GLY B . n 
B 1 372 TRP 372 372 372 TRP TRP B . n 
B 1 373 SER 373 373 373 SER SER B . n 
B 1 374 ALA 374 374 374 ALA ALA B . n 
B 1 375 LEU 375 375 375 LEU LEU B . n 
B 1 376 PHE 376 376 376 PHE PHE B . n 
B 1 377 SER 377 377 377 SER SER B . n 
B 1 378 GLU 378 378 378 GLU GLU B . n 
B 1 379 TYR 379 379 379 TYR TYR B . n 
B 1 380 PRO 380 380 380 PRO PRO B . n 
B 1 381 GLY 381 381 381 GLY GLY B . n 
B 1 382 PHE 382 382 382 PHE PHE B . n 
B 1 383 ALA 383 383 383 ALA ALA B . n 
B 1 384 THR 384 384 384 THR THR B . n 
B 1 385 ASP 385 385 385 ASP ASP B . n 
B 1 386 SER 386 386 386 SER SER B . n 
B 1 387 THR 387 387 387 THR THR B . n 
B 1 388 VAL 388 388 388 VAL VAL B . n 
B 1 389 ALA 389 389 389 ALA ALA B . n 
B 1 390 LEU 390 390 390 LEU LEU B . n 
B 1 391 LEU 391 391 391 LEU LEU B . n 
B 1 392 ILE 392 392 392 ILE ILE B . n 
B 1 393 GLY 393 393 393 GLY GLY B . n 
B 1 394 LEU 394 394 394 LEU LEU B . n 
B 1 395 LEU 395 395 395 LEU LEU B . n 
B 1 396 PHE 396 396 396 PHE PHE B . n 
B 1 397 PHE 397 397 397 PHE PHE B . n 
B 1 398 LEU 398 398 398 LEU LEU B . n 
B 1 399 ILE 399 399 399 ILE ILE B . n 
B 1 400 PRO 400 400 400 PRO PRO B . n 
B 1 401 ALA 401 401 401 ALA ALA B . n 
B 1 402 LYS 402 402 402 LYS LYS B . n 
B 1 403 THR 403 403 403 THR THR B . n 
B 1 404 LEU 404 404 404 LEU LEU B . n 
B 1 405 THR 405 405 ?   ?   ?   B . n 
B 1 406 LYS 406 406 ?   ?   ?   B . n 
B 1 407 THR 407 407 ?   ?   ?   B . n 
B 1 408 THR 408 408 ?   ?   ?   B . n 
B 1 409 PRO 409 409 ?   ?   ?   B . n 
B 1 410 THR 410 410 ?   ?   ?   B . n 
B 1 411 GLY 411 411 ?   ?   ?   B . n 
B 1 412 GLU 412 412 412 GLU GLU B . n 
B 1 413 ILE 413 413 413 ILE ILE B . n 
B 1 414 VAL 414 414 414 VAL VAL B . n 
B 1 415 ALA 415 415 415 ALA ALA B . n 
B 1 416 PHE 416 416 416 PHE PHE B . n 
B 1 417 ASP 417 417 417 ASP ASP B . n 
B 1 418 TYR 418 418 418 TYR TYR B . n 
B 1 419 SER 419 419 419 SER SER B . n 
B 1 420 PRO 420 420 420 PRO PRO B . n 
B 1 421 LEU 421 421 421 LEU LEU B . n 
B 1 422 ILE 422 422 422 ILE ILE B . n 
B 1 423 THR 423 423 423 THR THR B . n 
B 1 424 TRP 424 424 424 TRP TRP B . n 
B 1 425 LYS 425 425 425 LYS LYS B . n 
B 1 426 GLU 426 426 426 GLU GLU B . n 
B 1 427 PHE 427 427 427 PHE PHE B . n 
B 1 428 GLN 428 428 428 GLN GLN B . n 
B 1 429 SER 429 429 429 SER SER B . n 
B 1 430 PHE 430 430 430 PHE PHE B . n 
B 1 431 MET 431 431 431 MET MET B . n 
B 1 432 PRO 432 432 432 PRO PRO B . n 
B 1 433 TRP 433 433 433 TRP TRP B . n 
B 1 434 ASP 434 434 434 ASP ASP B . n 
B 1 435 ILE 435 435 435 ILE ILE B . n 
B 1 436 ALA 436 436 436 ALA ALA B . n 
B 1 437 ILE 437 437 437 ILE ILE B . n 
B 1 438 LEU 438 438 438 LEU LEU B . n 
B 1 439 VAL 439 439 439 VAL VAL B . n 
B 1 440 GLY 440 440 440 GLY GLY B . n 
B 1 441 GLY 441 441 441 GLY GLY B . n 
B 1 442 GLY 442 442 442 GLY GLY B . n 
B 1 443 PHE 443 443 443 PHE PHE B . n 
B 1 444 ALA 444 444 444 ALA ALA B . n 
B 1 445 LEU 445 445 445 LEU LEU B . n 
B 1 446 ALA 446 446 446 ALA ALA B . n 
B 1 447 ASP 447 447 447 ASP ASP B . n 
B 1 448 GLY 448 448 448 GLY GLY B . n 
B 1 449 CYS 449 449 449 CYS CYS B . n 
B 1 450 GLU 450 450 450 GLU GLU B . n 
B 1 451 GLU 451 451 451 GLU GLU B . n 
B 1 452 SER 452 452 452 SER SER B . n 
B 1 453 GLY 453 453 453 GLY GLY B . n 
B 1 454 LEU 454 454 454 LEU LEU B . n 
B 1 455 SER 455 455 455 SER SER B . n 
B 1 456 LYS 456 456 456 LYS LYS B . n 
B 1 457 TRP 457 457 457 TRP TRP B . n 
B 1 458 ILE 458 458 458 ILE ILE B . n 
B 1 459 GLY 459 459 459 GLY GLY B . n 
B 1 460 ASN 460 460 460 ASN ASN B . n 
B 1 461 LYS 461 461 461 LYS LYS B . n 
B 1 462 LEU 462 462 462 LEU LEU B . n 
B 1 463 SER 463 463 463 SER SER B . n 
B 1 464 PRO 464 464 464 PRO PRO B . n 
B 1 465 LEU 465 465 465 LEU LEU B . n 
B 1 466 GLY 466 466 466 GLY GLY B . n 
B 1 467 SER 467 467 467 SER SER B . n 
B 1 468 LEU 468 468 468 LEU LEU B . n 
B 1 469 PRO 469 469 469 PRO PRO B . n 
B 1 470 ALA 470 470 470 ALA ALA B . n 
B 1 471 TRP 471 471 471 TRP TRP B . n 
B 1 472 LEU 472 472 472 LEU LEU B . n 
B 1 473 ILE 473 473 473 ILE ILE B . n 
B 1 474 ILE 474 474 474 ILE ILE B . n 
B 1 475 LEU 475 475 475 LEU LEU B . n 
B 1 476 ILE 476 476 476 ILE ILE B . n 
B 1 477 SER 477 477 477 SER SER B . n 
B 1 478 SER 478 478 478 SER SER B . n 
B 1 479 LEU 479 479 479 LEU LEU B . n 
B 1 480 MET 480 480 480 MET MET B . n 
B 1 481 VAL 481 481 481 VAL VAL B . n 
B 1 482 THR 482 482 482 THR THR B . n 
B 1 483 SER 483 483 483 SER SER B . n 
B 1 484 LEU 484 484 484 LEU LEU B . n 
B 1 485 THR 485 485 485 THR THR B . n 
B 1 486 GLU 486 486 486 GLU GLU B . n 
B 1 487 VAL 487 487 487 VAL VAL B . n 
B 1 488 ALA 488 488 488 ALA ALA B . n 
B 1 489 SER 489 489 489 SER SER B . n 
B 1 490 ASN 490 490 490 ASN ASN B . n 
B 1 491 PRO 491 491 491 PRO PRO B . n 
B 1 492 ALA 492 492 492 ALA ALA B . n 
B 1 493 THR 493 493 493 THR THR B . n 
B 1 494 ILE 494 494 494 ILE ILE B . n 
B 1 495 THR 495 495 495 THR THR B . n 
B 1 496 LEU 496 496 496 LEU LEU B . n 
B 1 497 PHE 497 497 497 PHE PHE B . n 
B 1 498 LEU 498 498 498 LEU LEU B . n 
B 1 499 PRO 499 499 499 PRO PRO B . n 
B 1 500 ILE 500 500 500 ILE ILE B . n 
B 1 501 LEU 501 501 501 LEU LEU B . n 
B 1 502 SER 502 502 502 SER SER B . n 
B 1 503 PRO 503 503 503 PRO PRO B . n 
B 1 504 LEU 504 504 504 LEU LEU B . n 
B 1 505 ALA 505 505 505 ALA ALA B . n 
B 1 506 GLU 506 506 506 GLU GLU B . n 
B 1 507 ALA 507 507 507 ALA ALA B . n 
B 1 508 ILE 508 508 508 ILE ILE B . n 
B 1 509 HIS 509 509 509 HIS HIS B . n 
B 1 510 VAL 510 510 510 VAL VAL B . n 
B 1 511 ASN 511 511 511 ASN ASN B . n 
B 1 512 PRO 512 512 512 PRO PRO B . n 
B 1 513 LEU 513 513 513 LEU LEU B . n 
B 1 514 TYR 514 514 514 TYR TYR B . n 
B 1 515 ILE 515 515 515 ILE ILE B . n 
B 1 516 LEU 516 516 516 LEU LEU B . n 
B 1 517 ILE 517 517 517 ILE ILE B . n 
B 1 518 PRO 518 518 518 PRO PRO B . n 
B 1 519 SER 519 519 519 SER SER B . n 
B 1 520 THR 520 520 520 THR THR B . n 
B 1 521 LEU 521 521 521 LEU LEU B . n 
B 1 522 CYS 522 522 522 CYS CYS B . n 
B 1 523 THR 523 523 523 THR THR B . n 
B 1 524 SER 524 524 524 SER SER B . n 
B 1 525 PHE 525 525 525 PHE PHE B . n 
B 1 526 ALA 526 526 526 ALA ALA B . n 
B 1 527 PHE 527 527 527 PHE PHE B . n 
B 1 528 LEU 528 528 528 LEU LEU B . n 
B 1 529 LEU 529 529 529 LEU LEU B . n 
B 1 530 PRO 530 530 530 PRO PRO B . n 
B 1 531 VAL 531 531 531 VAL VAL B . n 
B 1 532 ALA 532 532 532 ALA ALA B . n 
B 1 533 ASN 533 533 533 ASN ASN B . n 
B 1 534 PRO 534 534 534 PRO PRO B . n 
B 1 535 PRO 535 535 535 PRO PRO B . n 
B 1 536 ASN 536 536 536 ASN ASN B . n 
B 1 537 ALA 537 537 537 ALA ALA B . n 
B 1 538 ILE 538 538 538 ILE ILE B . n 
B 1 539 VAL 539 539 539 VAL VAL B . n 
B 1 540 PHE 540 540 540 PHE PHE B . n 
B 1 541 SER 541 541 541 SER SER B . n 
B 1 542 TYR 542 542 542 TYR TYR B . n 
B 1 543 GLY 543 543 543 GLY GLY B . n 
B 1 544 HIS 544 544 544 HIS HIS B . n 
B 1 545 LEU 545 545 545 LEU LEU B . n 
B 1 546 LYS 546 546 546 LYS LYS B . n 
B 1 547 VAL 547 547 547 VAL VAL B . n 
B 1 548 ILE 548 548 548 ILE ILE B . n 
B 1 549 ASP 549 549 549 ASP ASP B . n 
B 1 550 MET 550 550 550 MET MET B . n 
B 1 551 VAL 551 551 551 VAL VAL B . n 
B 1 552 LYS 552 552 552 LYS LYS B . n 
B 1 553 ALA 553 553 553 ALA ALA B . n 
B 1 554 GLY 554 554 554 GLY GLY B . n 
B 1 555 LEU 555 555 555 LEU LEU B . n 
B 1 556 GLY 556 556 556 GLY GLY B . n 
B 1 557 VAL 557 557 557 VAL VAL B . n 
B 1 558 ASN 558 558 558 ASN ASN B . n 
B 1 559 ILE 559 559 559 ILE ILE B . n 
B 1 560 VAL 560 560 560 VAL VAL B . n 
B 1 561 GLY 561 561 561 GLY GLY B . n 
B 1 562 VAL 562 562 562 VAL VAL B . n 
B 1 563 ALA 563 563 563 ALA ALA B . n 
B 1 564 VAL 564 564 564 VAL VAL B . n 
B 1 565 VAL 565 565 565 VAL VAL B . n 
B 1 566 MET 566 566 566 MET MET B . n 
B 1 567 LEU 567 567 567 LEU LEU B . n 
B 1 568 GLY 568 568 568 GLY GLY B . n 
B 1 569 ILE 569 569 569 ILE ILE B . n 
B 1 570 CYS 570 570 570 CYS CYS B . n 
B 1 571 THR 571 571 571 THR THR B . n 
B 1 572 TRP 572 572 572 TRP TRP B . n 
B 1 573 ILE 573 573 573 ILE ILE B . n 
B 1 574 VAL 574 574 574 VAL VAL B . n 
B 1 575 PRO 575 575 575 PRO PRO B . n 
B 1 576 MET 576 576 576 MET MET B . n 
B 1 577 PHE 577 577 577 PHE PHE B . n 
B 1 578 ASP 578 578 578 ASP ASP B . n 
B 1 579 LEU 579 579 579 LEU LEU B . n 
B 1 580 TYR 580 580 580 TYR TYR B . n 
B 1 581 THR 581 581 581 THR THR B . n 
B 1 582 TYR 582 582 582 TYR TYR B . n 
B 1 583 PRO 583 583 583 PRO PRO B . n 
B 1 584 SER 584 584 584 SER SER B . n 
B 1 585 TRP 585 585 585 TRP TRP B . n 
B 1 586 ALA 586 586 586 ALA ALA B . n 
B 1 587 PRO 587 587 587 PRO PRO B . n 
B 1 588 ALA 588 588 588 ALA ALA B . n 
B 1 589 MET 589 589 ?   ?   ?   B . n 
B 1 590 SER 590 590 ?   ?   ?   B . n 
B 1 591 ASN 591 591 ?   ?   ?   B . n 
B 1 592 GLU 592 592 ?   ?   ?   B . n 
B 1 593 THR 593 593 ?   ?   ?   B . n 
B 1 594 MET 594 594 ?   ?   ?   B . n 
B 1 595 PRO 595 595 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 NA  1 601 601 NA  NA  A . 
D 3 SO4 1 602 602 SO4 SO4 A . 
E 2 NA  1 901 901 NA  NA  B . 
F 2 NA  1 902 902 NA  NA  B . 
G 3 SO4 1 903 903 SO4 SO4 B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A CYS 276 ? SG  ? A CYS 276 SG  
2  1 Y 1 B GLU 162 ? CG  ? B GLU 162 CG  
3  1 Y 1 B GLU 162 ? CD  ? B GLU 162 CD  
4  1 Y 1 B GLU 162 ? OE1 ? B GLU 162 OE1 
5  1 Y 1 B GLU 162 ? OE2 ? B GLU 162 OE2 
6  1 Y 1 B GLU 164 ? CG  ? B GLU 164 CG  
7  1 Y 1 B GLU 164 ? CD  ? B GLU 164 CD  
8  1 Y 1 B GLU 164 ? OE1 ? B GLU 164 OE1 
9  1 Y 1 B GLU 164 ? OE2 ? B GLU 164 OE2 
10 1 Y 1 B VAL 165 ? CG1 ? B VAL 165 CG1 
11 1 Y 1 B VAL 165 ? CG2 ? B VAL 165 CG2 
12 1 Y 1 B GLU 166 ? CG  ? B GLU 166 CG  
13 1 Y 1 B GLU 166 ? CD  ? B GLU 166 CD  
14 1 Y 1 B GLU 166 ? OE1 ? B GLU 166 OE1 
15 1 Y 1 B GLU 166 ? OE2 ? B GLU 166 OE2 
16 1 Y 1 B CYS 276 ? SG  ? B CYS 276 SG  
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Y5U 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8Y5U 
_struct.title                        'human NaS1 intermediate state 1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Y5U 
_struct_keywords.text            'membrane sodium anion transporter, PROTEIN TRANSPORT' 
_struct_keywords.pdbx_keywords   'PROTEIN TRANSPORT' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    S13A1_HUMAN 
_struct_ref.pdbx_db_accession          Q9BZW2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASA
YFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIIN
AEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT
CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGK
TKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIP
AKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM
VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIV
GVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP
;
_struct_ref.pdbx_align_begin           0 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8Y5U A 1 ? 595 ? Q9BZW2 1 ? 595 ? 1 595 
2 1 8Y5U B 1 ? 595 ? Q9BZW2 1 ? 595 ? 1 595 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 2   ? TYR A 10  ? LYS A 2   TYR A 10  1 ? 9  
HELX_P HELX_P2  AA2 TYR A 10  ? LEU A 23  ? TYR A 10  LEU A 23  1 ? 14 
HELX_P HELX_P3  AA3 LEU A 24  ? HIS A 31  ? LEU A 24  HIS A 31  1 ? 8  
HELX_P HELX_P4  AA4 THR A 32  ? GLU A 51  ? THR A 32  GLU A 51  1 ? 20 
HELX_P HELX_P5  AA5 PRO A 54  ? LEU A 60  ? PRO A 54  LEU A 60  1 ? 7  
HELX_P HELX_P6  AA6 LEU A 61  ? GLY A 70  ? LEU A 61  GLY A 70  1 ? 10 
HELX_P HELX_P7  AA7 PRO A 73  ? ALA A 80  ? PRO A 73  ALA A 80  1 ? 8  
HELX_P HELX_P8  AA8 LYS A 83  ? TRP A 102 ? LYS A 83  TRP A 102 1 ? 20 
HELX_P HELX_P9  AA9 ASN A 103 ? GLY A 117 ? ASN A 103 GLY A 117 1 ? 15 
HELX_P HELX_P10 AB1 ASN A 119 ? MET A 136 ? ASN A 119 MET A 136 1 ? 18 
HELX_P HELX_P11 AB2 SER A 139 ? ALA A 167 ? SER A 139 ALA A 167 1 ? 29 
HELX_P HELX_P12 AB3 LYS A 231 ? LEU A 253 ? LYS A 231 LEU A 253 1 ? 23 
HELX_P HELX_P13 AB4 THR A 259 ? TYR A 273 ? THR A 259 TYR A 273 1 ? 15 
HELX_P HELX_P14 AB5 ASN A 280 ? PHE A 307 ? ASN A 280 PHE A 307 1 ? 28 
HELX_P HELX_P15 AB6 THR A 323 ? GLY A 341 ? THR A 323 GLY A 341 1 ? 19 
HELX_P HELX_P16 AB7 ILE A 348 ? ASP A 365 ? ILE A 348 ASP A 365 1 ? 18 
HELX_P HELX_P17 AB8 THR A 384 ? LEU A 394 ? THR A 384 LEU A 394 1 ? 11 
HELX_P HELX_P18 AB9 LEU A 395 ? LEU A 398 ? LEU A 395 LEU A 398 5 ? 4  
HELX_P HELX_P19 AC1 THR A 423 ? SER A 429 ? THR A 423 SER A 429 1 ? 7  
HELX_P HELX_P20 AC2 PRO A 432 ? SER A 452 ? PRO A 432 SER A 452 1 ? 21 
HELX_P HELX_P21 AC3 GLY A 453 ? SER A 463 ? GLY A 453 SER A 463 1 ? 11 
HELX_P HELX_P22 AC4 PRO A 464 ? LEU A 468 ? PRO A 464 LEU A 468 5 ? 5  
HELX_P HELX_P23 AC5 PRO A 469 ? THR A 485 ? PRO A 469 THR A 485 1 ? 17 
HELX_P HELX_P24 AC6 SER A 489 ? ILE A 508 ? SER A 489 ILE A 508 1 ? 20 
HELX_P HELX_P25 AC7 ASN A 511 ? SER A 524 ? ASN A 511 SER A 524 1 ? 14 
HELX_P HELX_P26 AC8 ASN A 533 ? SER A 541 ? ASN A 533 SER A 541 1 ? 9  
HELX_P HELX_P27 AC9 LYS A 546 ? TRP A 572 ? LYS A 546 TRP A 572 1 ? 27 
HELX_P HELX_P28 AD1 TRP A 572 ? ASP A 578 ? TRP A 572 ASP A 578 1 ? 7  
HELX_P HELX_P29 AD2 PHE B 3   ? TYR B 10  ? PHE B 3   TYR B 10  1 ? 8  
HELX_P HELX_P30 AD3 TYR B 10  ? LEU B 23  ? TYR B 10  LEU B 23  1 ? 14 
HELX_P HELX_P31 AD4 LEU B 24  ? VAL B 29  ? LEU B 24  VAL B 29  1 ? 6  
HELX_P HELX_P32 AD5 LEU B 30  ? LYS B 33  ? LEU B 30  LYS B 33  5 ? 4  
HELX_P HELX_P33 AD6 GLU B 34  ? THR B 50  ? GLU B 34  THR B 50  1 ? 17 
HELX_P HELX_P34 AD7 PRO B 54  ? LEU B 60  ? PRO B 54  LEU B 60  1 ? 7  
HELX_P HELX_P35 AD8 LEU B 61  ? PHE B 69  ? LEU B 61  PHE B 69  1 ? 9  
HELX_P HELX_P36 AD9 PRO B 73  ? ALA B 80  ? PRO B 73  ALA B 80  1 ? 8  
HELX_P HELX_P37 AE1 LYS B 83  ? TRP B 102 ? LYS B 83  TRP B 102 1 ? 20 
HELX_P HELX_P38 AE2 ASN B 103 ? VAL B 116 ? ASN B 103 VAL B 116 1 ? 14 
HELX_P HELX_P39 AE3 ASN B 119 ? SER B 135 ? ASN B 119 SER B 135 1 ? 17 
HELX_P HELX_P40 AE4 SER B 139 ? GLU B 162 ? SER B 139 GLU B 162 1 ? 24 
HELX_P HELX_P41 AE5 LYS B 231 ? TYR B 246 ? LYS B 231 TYR B 246 1 ? 16 
HELX_P HELX_P42 AE6 THR B 259 ? TYR B 273 ? THR B 259 TYR B 273 1 ? 15 
HELX_P HELX_P43 AE7 SER B 283 ? PHE B 307 ? SER B 283 PHE B 307 1 ? 25 
HELX_P HELX_P44 AE8 ASN B 311 ? PHE B 316 ? ASN B 311 PHE B 316 1 ? 6  
HELX_P HELX_P45 AE9 VAL B 324 ? GLY B 341 ? VAL B 324 GLY B 341 1 ? 18 
HELX_P HELX_P46 AF1 ARG B 344 ? SER B 363 ? ARG B 344 SER B 363 1 ? 20 
HELX_P HELX_P47 AF2 GLY B 371 ? SER B 377 ? GLY B 371 SER B 377 5 ? 7  
HELX_P HELX_P48 AF3 THR B 384 ? LEU B 394 ? THR B 384 LEU B 394 1 ? 11 
HELX_P HELX_P49 AF4 LEU B 395 ? LEU B 398 ? LEU B 395 LEU B 398 5 ? 4  
HELX_P HELX_P50 AF5 THR B 423 ? SER B 429 ? THR B 423 SER B 429 1 ? 7  
HELX_P HELX_P51 AF6 PRO B 432 ? SER B 452 ? PRO B 432 SER B 452 1 ? 21 
HELX_P HELX_P52 AF7 LEU B 454 ? SER B 463 ? LEU B 454 SER B 463 1 ? 10 
HELX_P HELX_P53 AF8 PRO B 469 ? THR B 485 ? PRO B 469 THR B 485 1 ? 17 
HELX_P HELX_P54 AF9 SER B 489 ? ILE B 508 ? SER B 489 ILE B 508 1 ? 20 
HELX_P HELX_P55 AG1 PRO B 512 ? SER B 524 ? PRO B 512 SER B 524 1 ? 13 
HELX_P HELX_P56 AG2 ASN B 533 ? SER B 541 ? ASN B 533 SER B 541 1 ? 9  
HELX_P HELX_P57 AG3 LYS B 546 ? THR B 571 ? LYS B 546 THR B 571 1 ? 26 
HELX_P HELX_P58 AG4 TRP B 572 ? ASP B 578 ? TRP B 572 ASP B 578 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A THR 485 O   ? ? ? 1_555 C NA . NA ? ? A THR 485 A NA 601 1_555 ? ? ? ? ? ? ? 2.483 ? ? 
metalc2  metalc ? ? A THR 485 OG1 ? ? ? 1_555 C NA . NA ? ? A THR 485 A NA 601 1_555 ? ? ? ? ? ? ? 2.723 ? ? 
metalc3  metalc ? ? A ALA 488 O   ? ? ? 1_555 C NA . NA ? ? A ALA 488 A NA 601 1_555 ? ? ? ? ? ? ? 2.457 ? ? 
metalc4  metalc ? ? A ASN 490 OD1 ? ? ? 1_555 C NA . NA ? ? A ASN 490 A NA 601 1_555 ? ? ? ? ? ? ? 2.430 ? ? 
metalc5  metalc ? ? A ALA 532 O   ? ? ? 1_555 C NA . NA ? ? A ALA 532 A NA 601 1_555 ? ? ? ? ? ? ? 2.430 ? ? 
metalc6  metalc ? ? B SER 135 O   ? ? ? 1_555 E NA . NA ? ? B SER 135 B NA 901 1_555 ? ? ? ? ? ? ? 2.464 ? ? 
metalc7  metalc ? ? B SER 135 OG  ? ? ? 1_555 E NA . NA ? ? B SER 135 B NA 901 1_555 ? ? ? ? ? ? ? 2.864 ? ? 
metalc8  metalc ? ? B GLY 258 O   ? ? ? 1_555 E NA . NA ? ? B GLY 258 B NA 901 1_555 ? ? ? ? ? ? ? 2.382 ? ? 
metalc9  metalc ? ? B THR 485 O   ? ? ? 1_555 F NA . NA ? ? B THR 485 B NA 902 1_555 ? ? ? ? ? ? ? 2.438 ? ? 
metalc10 metalc ? ? B THR 485 OG1 ? ? ? 1_555 F NA . NA ? ? B THR 485 B NA 902 1_555 ? ? ? ? ? ? ? 2.540 ? ? 
metalc11 metalc ? ? B ALA 488 O   ? ? ? 1_555 F NA . NA ? ? B ALA 488 B NA 902 1_555 ? ? ? ? ? ? ? 2.474 ? ? 
metalc12 metalc ? ? B ASN 490 OD1 ? ? ? 1_555 F NA . NA ? ? B ASN 490 B NA 902 1_555 ? ? ? ? ? ? ? 2.483 ? ? 
metalc13 metalc ? ? B ALA 532 O   ? ? ? 1_555 F NA . NA ? ? B ALA 532 B NA 902 1_555 ? ? ? ? ? ? ? 2.441 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? A THR 485 ? A THR 485 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 OG1 ? A THR 485 ? A THR 485 ? 1_555 65.8  ? 
2  O   ? A THR 485 ? A THR 485 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 O   ? A ALA 488 ? A ALA 488 ? 1_555 68.9  ? 
3  OG1 ? A THR 485 ? A THR 485 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 O   ? A ALA 488 ? A ALA 488 ? 1_555 97.9  ? 
4  O   ? A THR 485 ? A THR 485 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 OD1 ? A ASN 490 ? A ASN 490 ? 1_555 129.6 ? 
5  OG1 ? A THR 485 ? A THR 485 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 OD1 ? A ASN 490 ? A ASN 490 ? 1_555 73.9  ? 
6  O   ? A ALA 488 ? A ALA 488 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 OD1 ? A ASN 490 ? A ASN 490 ? 1_555 148.0 ? 
7  O   ? A THR 485 ? A THR 485 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 O   ? A ALA 532 ? A ALA 532 ? 1_555 97.2  ? 
8  OG1 ? A THR 485 ? A THR 485 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 O   ? A ALA 532 ? A ALA 532 ? 1_555 162.3 ? 
9  O   ? A ALA 488 ? A ALA 488 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 O   ? A ALA 532 ? A ALA 532 ? 1_555 79.5  ? 
10 OD1 ? A ASN 490 ? A ASN 490 ? 1_555 NA ? C NA . ? A NA 601 ? 1_555 O   ? A ALA 532 ? A ALA 532 ? 1_555 117.3 ? 
11 O   ? B SER 135 ? B SER 135 ? 1_555 NA ? E NA . ? B NA 901 ? 1_555 OG  ? B SER 135 ? B SER 135 ? 1_555 59.7  ? 
12 O   ? B SER 135 ? B SER 135 ? 1_555 NA ? E NA . ? B NA 901 ? 1_555 O   ? B GLY 258 ? B GLY 258 ? 1_555 126.1 ? 
13 OG  ? B SER 135 ? B SER 135 ? 1_555 NA ? E NA . ? B NA 901 ? 1_555 O   ? B GLY 258 ? B GLY 258 ? 1_555 167.0 ? 
14 O   ? B THR 485 ? B THR 485 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 OG1 ? B THR 485 ? B THR 485 ? 1_555 65.4  ? 
15 O   ? B THR 485 ? B THR 485 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 O   ? B ALA 488 ? B ALA 488 ? 1_555 74.8  ? 
16 OG1 ? B THR 485 ? B THR 485 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 O   ? B ALA 488 ? B ALA 488 ? 1_555 88.7  ? 
17 O   ? B THR 485 ? B THR 485 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 OD1 ? B ASN 490 ? B ASN 490 ? 1_555 132.3 ? 
18 OG1 ? B THR 485 ? B THR 485 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 OD1 ? B ASN 490 ? B ASN 490 ? 1_555 68.3  ? 
19 O   ? B ALA 488 ? B ALA 488 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 OD1 ? B ASN 490 ? B ASN 490 ? 1_555 115.1 ? 
20 O   ? B THR 485 ? B THR 485 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 O   ? B ALA 532 ? B ALA 532 ? 1_555 124.5 ? 
21 OG1 ? B THR 485 ? B THR 485 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 O   ? B ALA 532 ? B ALA 532 ? 1_555 165.1 ? 
22 O   ? B ALA 488 ? B ALA 488 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 O   ? B ALA 532 ? B ALA 532 ? 1_555 104.3 ? 
23 OD1 ? B ASN 490 ? B ASN 490 ? 1_555 NA ? F NA . ? B NA 902 ? 1_555 O   ? B ALA 532 ? B ALA 532 ? 1_555 99.1  ? 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PRO B 400 ? THR B 403 ? PRO B 400 THR B 403 
AA1 2 TYR B 418 ? PRO B 420 ? TYR B 418 PRO B 420 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   ALA 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   B 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    401 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    ALA 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    B 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     401 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   SER 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   B 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    419 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    SER 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    B 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     419 
# 
_pdbx_entry_details.entry_id                   8Y5U 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PHE A 307 ? ? -95.88  -60.66  
2  1 GLN A 346 ? ? 68.35   -5.74   
3  1 ILE A 348 ? ? 62.94   -57.78  
4  1 ALA A 374 ? ? 67.74   -3.88   
5  1 THR A 384 ? ? -125.50 -169.78 
6  1 LEU A 421 ? ? 74.67   -13.26  
7  1 PRO A 464 ? ? -66.95  5.77    
8  1 LEU A 465 ? ? -66.59  1.40    
9  1 THR A 571 ? ? -93.65  -62.65  
10 1 TYR B 10  ? ? -97.53  56.70   
11 1 SER B 139 ? ? 177.46  167.39  
12 1 LEU B 308 ? ? 62.02   -163.26 
13 1 ASP B 365 ? ? -161.50 79.54   
14 1 PHE B 376 ? ? -99.68  35.43   
15 1 SER B 377 ? ? -79.74  48.79   
16 1 ASP B 417 ? ? -167.52 -168.69 
17 1 PHE B 430 ? ? 69.87   -7.45   
18 1 THR B 485 ? ? -69.92  0.64    
19 1 ASN B 511 ? ? 35.60   77.10   
20 1 LEU B 529 ? ? 63.84   159.36  
21 1 PRO B 530 ? ? -72.88  -168.37 
22 1 VAL B 531 ? ? 58.67   -27.82  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8Y5U 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8Y5U 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.04 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               102182 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.2 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'membrane sodium anion transproter 1' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8Y5U 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8Y5U 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8Y5U 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A THR 168 ? A THR 168 
3   1 Y 1 A GLN 169 ? A GLN 169 
4   1 Y 1 A MET 170 ? A MET 170 
5   1 Y 1 A THR 171 ? A THR 171 
6   1 Y 1 A TYR 172 ? A TYR 172 
7   1 Y 1 A PHE 173 ? A PHE 173 
8   1 Y 1 A ASN 174 ? A ASN 174 
9   1 Y 1 A GLY 175 ? A GLY 175 
10  1 Y 1 A SER 176 ? A SER 176 
11  1 Y 1 A THR 177 ? A THR 177 
12  1 Y 1 A ASN 178 ? A ASN 178 
13  1 Y 1 A HIS 179 ? A HIS 179 
14  1 Y 1 A GLY 180 ? A GLY 180 
15  1 Y 1 A LEU 181 ? A LEU 181 
16  1 Y 1 A GLU 182 ? A GLU 182 
17  1 Y 1 A ILE 183 ? A ILE 183 
18  1 Y 1 A ASP 184 ? A ASP 184 
19  1 Y 1 A GLU 185 ? A GLU 185 
20  1 Y 1 A SER 186 ? A SER 186 
21  1 Y 1 A VAL 187 ? A VAL 187 
22  1 Y 1 A ASN 188 ? A ASN 188 
23  1 Y 1 A GLY 189 ? A GLY 189 
24  1 Y 1 A HIS 190 ? A HIS 190 
25  1 Y 1 A GLU 191 ? A GLU 191 
26  1 Y 1 A ILE 192 ? A ILE 192 
27  1 Y 1 A ASN 193 ? A ASN 193 
28  1 Y 1 A GLU 194 ? A GLU 194 
29  1 Y 1 A ARG 195 ? A ARG 195 
30  1 Y 1 A LYS 196 ? A LYS 196 
31  1 Y 1 A GLU 197 ? A GLU 197 
32  1 Y 1 A LYS 198 ? A LYS 198 
33  1 Y 1 A THR 199 ? A THR 199 
34  1 Y 1 A LYS 200 ? A LYS 200 
35  1 Y 1 A PRO 201 ? A PRO 201 
36  1 Y 1 A VAL 202 ? A VAL 202 
37  1 Y 1 A PRO 203 ? A PRO 203 
38  1 Y 1 A GLY 204 ? A GLY 204 
39  1 Y 1 A TYR 205 ? A TYR 205 
40  1 Y 1 A ASN 206 ? A ASN 206 
41  1 Y 1 A ASN 207 ? A ASN 207 
42  1 Y 1 A ASP 208 ? A ASP 208 
43  1 Y 1 A THR 209 ? A THR 209 
44  1 Y 1 A GLY 210 ? A GLY 210 
45  1 Y 1 A LYS 211 ? A LYS 211 
46  1 Y 1 A ILE 212 ? A ILE 212 
47  1 Y 1 A SER 213 ? A SER 213 
48  1 Y 1 A SER 214 ? A SER 214 
49  1 Y 1 A LYS 215 ? A LYS 215 
50  1 Y 1 A VAL 216 ? A VAL 216 
51  1 Y 1 A GLU 217 ? A GLU 217 
52  1 Y 1 A LEU 218 ? A LEU 218 
53  1 Y 1 A GLU 219 ? A GLU 219 
54  1 Y 1 A LYS 220 ? A LYS 220 
55  1 Y 1 A ASN 221 ? A ASN 221 
56  1 Y 1 A SER 222 ? A SER 222 
57  1 Y 1 A GLY 223 ? A GLY 223 
58  1 Y 1 A MET 224 ? A MET 224 
59  1 Y 1 A ARG 225 ? A ARG 225 
60  1 Y 1 A THR 226 ? A THR 226 
61  1 Y 1 A LYS 227 ? A LYS 227 
62  1 Y 1 A TYR 228 ? A TYR 228 
63  1 Y 1 A ARG 229 ? A ARG 229 
64  1 Y 1 A CYS 318 ? A CYS 318 
65  1 Y 1 A GLY 319 ? A GLY 319 
66  1 Y 1 A LYS 320 ? A LYS 320 
67  1 Y 1 A THR 321 ? A THR 321 
68  1 Y 1 A GLY 367 ? A GLY 367 
69  1 Y 1 A PHE 368 ? A PHE 368 
70  1 Y 1 A VAL 369 ? A VAL 369 
71  1 Y 1 A PRO 370 ? A PRO 370 
72  1 Y 1 A GLY 371 ? A GLY 371 
73  1 Y 1 A TRP 372 ? A TRP 372 
74  1 Y 1 A THR 405 ? A THR 405 
75  1 Y 1 A LYS 406 ? A LYS 406 
76  1 Y 1 A THR 407 ? A THR 407 
77  1 Y 1 A THR 408 ? A THR 408 
78  1 Y 1 A PRO 409 ? A PRO 409 
79  1 Y 1 A THR 410 ? A THR 410 
80  1 Y 1 A GLY 411 ? A GLY 411 
81  1 Y 1 A GLU 412 ? A GLU 412 
82  1 Y 1 A ILE 413 ? A ILE 413 
83  1 Y 1 A VAL 414 ? A VAL 414 
84  1 Y 1 A MET 589 ? A MET 589 
85  1 Y 1 A SER 590 ? A SER 590 
86  1 Y 1 A ASN 591 ? A ASN 591 
87  1 Y 1 A GLU 592 ? A GLU 592 
88  1 Y 1 A THR 593 ? A THR 593 
89  1 Y 1 A MET 594 ? A MET 594 
90  1 Y 1 A PRO 595 ? A PRO 595 
91  1 Y 1 B MET 1   ? B MET 1   
92  1 Y 1 B ALA 167 ? B ALA 167 
93  1 Y 1 B THR 168 ? B THR 168 
94  1 Y 1 B GLN 169 ? B GLN 169 
95  1 Y 1 B MET 170 ? B MET 170 
96  1 Y 1 B THR 171 ? B THR 171 
97  1 Y 1 B TYR 172 ? B TYR 172 
98  1 Y 1 B PHE 173 ? B PHE 173 
99  1 Y 1 B ASN 174 ? B ASN 174 
100 1 Y 1 B GLY 175 ? B GLY 175 
101 1 Y 1 B SER 176 ? B SER 176 
102 1 Y 1 B THR 177 ? B THR 177 
103 1 Y 1 B ASN 178 ? B ASN 178 
104 1 Y 1 B HIS 179 ? B HIS 179 
105 1 Y 1 B GLY 180 ? B GLY 180 
106 1 Y 1 B LEU 181 ? B LEU 181 
107 1 Y 1 B GLU 182 ? B GLU 182 
108 1 Y 1 B ILE 183 ? B ILE 183 
109 1 Y 1 B ASP 184 ? B ASP 184 
110 1 Y 1 B GLU 185 ? B GLU 185 
111 1 Y 1 B SER 186 ? B SER 186 
112 1 Y 1 B VAL 187 ? B VAL 187 
113 1 Y 1 B ASN 188 ? B ASN 188 
114 1 Y 1 B GLY 189 ? B GLY 189 
115 1 Y 1 B HIS 190 ? B HIS 190 
116 1 Y 1 B GLU 191 ? B GLU 191 
117 1 Y 1 B ILE 192 ? B ILE 192 
118 1 Y 1 B ASN 193 ? B ASN 193 
119 1 Y 1 B GLU 194 ? B GLU 194 
120 1 Y 1 B ARG 195 ? B ARG 195 
121 1 Y 1 B LYS 196 ? B LYS 196 
122 1 Y 1 B GLU 197 ? B GLU 197 
123 1 Y 1 B LYS 198 ? B LYS 198 
124 1 Y 1 B THR 199 ? B THR 199 
125 1 Y 1 B LYS 200 ? B LYS 200 
126 1 Y 1 B PRO 201 ? B PRO 201 
127 1 Y 1 B VAL 202 ? B VAL 202 
128 1 Y 1 B PRO 203 ? B PRO 203 
129 1 Y 1 B GLY 204 ? B GLY 204 
130 1 Y 1 B TYR 205 ? B TYR 205 
131 1 Y 1 B ASN 206 ? B ASN 206 
132 1 Y 1 B ASN 207 ? B ASN 207 
133 1 Y 1 B ASP 208 ? B ASP 208 
134 1 Y 1 B THR 209 ? B THR 209 
135 1 Y 1 B GLY 210 ? B GLY 210 
136 1 Y 1 B LYS 211 ? B LYS 211 
137 1 Y 1 B ILE 212 ? B ILE 212 
138 1 Y 1 B SER 213 ? B SER 213 
139 1 Y 1 B SER 214 ? B SER 214 
140 1 Y 1 B LYS 215 ? B LYS 215 
141 1 Y 1 B VAL 216 ? B VAL 216 
142 1 Y 1 B GLU 217 ? B GLU 217 
143 1 Y 1 B LEU 218 ? B LEU 218 
144 1 Y 1 B GLU 219 ? B GLU 219 
145 1 Y 1 B LYS 220 ? B LYS 220 
146 1 Y 1 B ASN 221 ? B ASN 221 
147 1 Y 1 B SER 222 ? B SER 222 
148 1 Y 1 B GLY 223 ? B GLY 223 
149 1 Y 1 B MET 224 ? B MET 224 
150 1 Y 1 B ARG 225 ? B ARG 225 
151 1 Y 1 B THR 226 ? B THR 226 
152 1 Y 1 B LYS 227 ? B LYS 227 
153 1 Y 1 B TYR 228 ? B TYR 228 
154 1 Y 1 B ARG 229 ? B ARG 229 
155 1 Y 1 B LYS 317 ? B LYS 317 
156 1 Y 1 B CYS 318 ? B CYS 318 
157 1 Y 1 B GLY 319 ? B GLY 319 
158 1 Y 1 B LYS 320 ? B LYS 320 
159 1 Y 1 B THR 321 ? B THR 321 
160 1 Y 1 B LYS 322 ? B LYS 322 
161 1 Y 1 B THR 405 ? B THR 405 
162 1 Y 1 B LYS 406 ? B LYS 406 
163 1 Y 1 B THR 407 ? B THR 407 
164 1 Y 1 B THR 408 ? B THR 408 
165 1 Y 1 B PRO 409 ? B PRO 409 
166 1 Y 1 B THR 410 ? B THR 410 
167 1 Y 1 B GLY 411 ? B GLY 411 
168 1 Y 1 B MET 589 ? B MET 589 
169 1 Y 1 B SER 590 ? B SER 590 
170 1 Y 1 B ASN 591 ? B ASN 591 
171 1 Y 1 B GLU 592 ? B GLU 592 
172 1 Y 1 B THR 593 ? B THR 593 
173 1 Y 1 B MET 594 ? B MET 594 
174 1 Y 1 B PRO 595 ? B PRO 595 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
NA  NA   NA N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
SO4 S    S  N N 302 
SO4 O1   O  N N 303 
SO4 O2   O  N N 304 
SO4 O3   O  N N 305 
SO4 O4   O  N N 306 
THR N    N  N N 307 
THR CA   C  N S 308 
THR C    C  N N 309 
THR O    O  N N 310 
THR CB   C  N R 311 
THR OG1  O  N N 312 
THR CG2  C  N N 313 
THR OXT  O  N N 314 
THR H    H  N N 315 
THR H2   H  N N 316 
THR HA   H  N N 317 
THR HB   H  N N 318 
THR HG1  H  N N 319 
THR HG21 H  N N 320 
THR HG22 H  N N 321 
THR HG23 H  N N 322 
THR HXT  H  N N 323 
TRP N    N  N N 324 
TRP CA   C  N S 325 
TRP C    C  N N 326 
TRP O    O  N N 327 
TRP CB   C  N N 328 
TRP CG   C  Y N 329 
TRP CD1  C  Y N 330 
TRP CD2  C  Y N 331 
TRP NE1  N  Y N 332 
TRP CE2  C  Y N 333 
TRP CE3  C  Y N 334 
TRP CZ2  C  Y N 335 
TRP CZ3  C  Y N 336 
TRP CH2  C  Y N 337 
TRP OXT  O  N N 338 
TRP H    H  N N 339 
TRP H2   H  N N 340 
TRP HA   H  N N 341 
TRP HB2  H  N N 342 
TRP HB3  H  N N 343 
TRP HD1  H  N N 344 
TRP HE1  H  N N 345 
TRP HE3  H  N N 346 
TRP HZ2  H  N N 347 
TRP HZ3  H  N N 348 
TRP HH2  H  N N 349 
TRP HXT  H  N N 350 
TYR N    N  N N 351 
TYR CA   C  N S 352 
TYR C    C  N N 353 
TYR O    O  N N 354 
TYR CB   C  N N 355 
TYR CG   C  Y N 356 
TYR CD1  C  Y N 357 
TYR CD2  C  Y N 358 
TYR CE1  C  Y N 359 
TYR CE2  C  Y N 360 
TYR CZ   C  Y N 361 
TYR OH   O  N N 362 
TYR OXT  O  N N 363 
TYR H    H  N N 364 
TYR H2   H  N N 365 
TYR HA   H  N N 366 
TYR HB2  H  N N 367 
TYR HB3  H  N N 368 
TYR HD1  H  N N 369 
TYR HD2  H  N N 370 
TYR HE1  H  N N 371 
TYR HE2  H  N N 372 
TYR HH   H  N N 373 
TYR HXT  H  N N 374 
VAL N    N  N N 375 
VAL CA   C  N S 376 
VAL C    C  N N 377 
VAL O    O  N N 378 
VAL CB   C  N N 379 
VAL CG1  C  N N 380 
VAL CG2  C  N N 381 
VAL OXT  O  N N 382 
VAL H    H  N N 383 
VAL H2   H  N N 384 
VAL HA   H  N N 385 
VAL HB   H  N N 386 
VAL HG11 H  N N 387 
VAL HG12 H  N N 388 
VAL HG13 H  N N 389 
VAL HG21 H  N N 390 
VAL HG22 H  N N 391 
VAL HG23 H  N N 392 
VAL HXT  H  N N 393 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
SO4 S   O1   doub N N 288 
SO4 S   O2   doub N N 289 
SO4 S   O3   sing N N 290 
SO4 S   O4   sing N N 291 
THR N   CA   sing N N 292 
THR N   H    sing N N 293 
THR N   H2   sing N N 294 
THR CA  C    sing N N 295 
THR CA  CB   sing N N 296 
THR CA  HA   sing N N 297 
THR C   O    doub N N 298 
THR C   OXT  sing N N 299 
THR CB  OG1  sing N N 300 
THR CB  CG2  sing N N 301 
THR CB  HB   sing N N 302 
THR OG1 HG1  sing N N 303 
THR CG2 HG21 sing N N 304 
THR CG2 HG22 sing N N 305 
THR CG2 HG23 sing N N 306 
THR OXT HXT  sing N N 307 
TRP N   CA   sing N N 308 
TRP N   H    sing N N 309 
TRP N   H2   sing N N 310 
TRP CA  C    sing N N 311 
TRP CA  CB   sing N N 312 
TRP CA  HA   sing N N 313 
TRP C   O    doub N N 314 
TRP C   OXT  sing N N 315 
TRP CB  CG   sing N N 316 
TRP CB  HB2  sing N N 317 
TRP CB  HB3  sing N N 318 
TRP CG  CD1  doub Y N 319 
TRP CG  CD2  sing Y N 320 
TRP CD1 NE1  sing Y N 321 
TRP CD1 HD1  sing N N 322 
TRP CD2 CE2  doub Y N 323 
TRP CD2 CE3  sing Y N 324 
TRP NE1 CE2  sing Y N 325 
TRP NE1 HE1  sing N N 326 
TRP CE2 CZ2  sing Y N 327 
TRP CE3 CZ3  doub Y N 328 
TRP CE3 HE3  sing N N 329 
TRP CZ2 CH2  doub Y N 330 
TRP CZ2 HZ2  sing N N 331 
TRP CZ3 CH2  sing Y N 332 
TRP CZ3 HZ3  sing N N 333 
TRP CH2 HH2  sing N N 334 
TRP OXT HXT  sing N N 335 
TYR N   CA   sing N N 336 
TYR N   H    sing N N 337 
TYR N   H2   sing N N 338 
TYR CA  C    sing N N 339 
TYR CA  CB   sing N N 340 
TYR CA  HA   sing N N 341 
TYR C   O    doub N N 342 
TYR C   OXT  sing N N 343 
TYR CB  CG   sing N N 344 
TYR CB  HB2  sing N N 345 
TYR CB  HB3  sing N N 346 
TYR CG  CD1  doub Y N 347 
TYR CG  CD2  sing Y N 348 
TYR CD1 CE1  sing Y N 349 
TYR CD1 HD1  sing N N 350 
TYR CD2 CE2  doub Y N 351 
TYR CD2 HD2  sing N N 352 
TYR CE1 CZ   doub Y N 353 
TYR CE1 HE1  sing N N 354 
TYR CE2 CZ   sing Y N 355 
TYR CE2 HE2  sing N N 356 
TYR CZ  OH   sing N N 357 
TYR OH  HH   sing N N 358 
TYR OXT HXT  sing N N 359 
VAL N   CA   sing N N 360 
VAL N   H    sing N N 361 
VAL N   H2   sing N N 362 
VAL CA  C    sing N N 363 
VAL CA  CB   sing N N 364 
VAL CA  HA   sing N N 365 
VAL C   O    doub N N 366 
VAL C   OXT  sing N N 367 
VAL CB  CG1  sing N N 368 
VAL CB  CG2  sing N N 369 
VAL CB  HB   sing N N 370 
VAL CG1 HG11 sing N N 371 
VAL CG1 HG12 sing N N 372 
VAL CG1 HG13 sing N N 373 
VAL CG2 HG21 sing N N 374 
VAL CG2 HG22 sing N N 375 
VAL CG2 HG23 sing N N 376 
VAL OXT HXT  sing N N 377 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-02-01 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8Y5U 
_em_admin.last_update        2025-01-22 
_em_admin.map_release_date   2025-01-22 
_em_admin.title              'human NaS1 intermediate state 1' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32030056 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8Y5U 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
N  
NA 
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . LYS A 1 2   ? 107.017 88.609  112.392 1.00 70.25  ? 2   LYS A N   1 
ATOM   2    C  CA  . LYS A 1 2   ? 108.167 87.714  112.418 1.00 70.25  ? 2   LYS A CA  1 
ATOM   3    C  C   . LYS A 1 2   ? 109.462 88.493  112.612 1.00 70.25  ? 2   LYS A C   1 
ATOM   4    O  O   . LYS A 1 2   ? 109.444 89.643  113.050 1.00 70.25  ? 2   LYS A O   1 
ATOM   5    C  CB  . LYS A 1 2   ? 108.235 86.891  111.130 1.00 70.25  ? 2   LYS A CB  1 
ATOM   6    C  CG  . LYS A 1 2   ? 108.046 87.704  109.861 1.00 70.25  ? 2   LYS A CG  1 
ATOM   7    C  CD  . LYS A 1 2   ? 108.113 86.821  108.627 1.00 70.25  ? 2   LYS A CD  1 
ATOM   8    C  CE  . LYS A 1 2   ? 107.692 87.580  107.379 1.00 70.25  ? 2   LYS A CE  1 
ATOM   9    N  NZ  . LYS A 1 2   ? 106.262 87.993  107.432 1.00 70.25  ? 2   LYS A NZ  1 
ATOM   10   N  N   . PHE A 1 3   ? 110.587 87.852  112.287 1.00 72.77  ? 3   PHE A N   1 
ATOM   11   C  CA  . PHE A 1 3   ? 111.882 88.509  112.431 1.00 72.77  ? 3   PHE A CA  1 
ATOM   12   C  C   . PHE A 1 3   ? 111.996 89.720  111.515 1.00 72.77  ? 3   PHE A C   1 
ATOM   13   O  O   . PHE A 1 3   ? 112.517 90.767  111.918 1.00 72.77  ? 3   PHE A O   1 
ATOM   14   C  CB  . PHE A 1 3   ? 113.010 87.518  112.142 1.00 72.77  ? 3   PHE A CB  1 
ATOM   15   C  CG  . PHE A 1 3   ? 113.110 86.402  113.141 1.00 72.77  ? 3   PHE A CG  1 
ATOM   16   C  CD1 . PHE A 1 3   ? 113.778 86.585  114.340 1.00 72.77  ? 3   PHE A CD1 1 
ATOM   17   C  CD2 . PHE A 1 3   ? 112.538 85.167  112.880 1.00 72.77  ? 3   PHE A CD2 1 
ATOM   18   C  CE1 . PHE A 1 3   ? 113.873 85.558  115.261 1.00 72.77  ? 3   PHE A CE1 1 
ATOM   19   C  CE2 . PHE A 1 3   ? 112.629 84.135  113.797 1.00 72.77  ? 3   PHE A CE2 1 
ATOM   20   C  CZ  . PHE A 1 3   ? 113.297 84.332  114.989 1.00 72.77  ? 3   PHE A CZ  1 
ATOM   21   N  N   . PHE A 1 4   ? 111.517 89.595  110.275 1.00 71.67  ? 4   PHE A N   1 
ATOM   22   C  CA  . PHE A 1 4   ? 111.679 90.674  109.306 1.00 71.67  ? 4   PHE A CA  1 
ATOM   23   C  C   . PHE A 1 4   ? 110.911 91.923  109.721 1.00 71.67  ? 4   PHE A C   1 
ATOM   24   O  O   . PHE A 1 4   ? 111.417 93.041  109.579 1.00 71.67  ? 4   PHE A O   1 
ATOM   25   C  CB  . PHE A 1 4   ? 111.243 90.200  107.922 1.00 71.67  ? 4   PHE A CB  1 
ATOM   26   C  CG  . PHE A 1 4   ? 112.166 89.181  107.318 1.00 71.67  ? 4   PHE A CG  1 
ATOM   27   C  CD1 . PHE A 1 4   ? 113.276 89.577  106.592 1.00 71.67  ? 4   PHE A CD1 1 
ATOM   28   C  CD2 . PHE A 1 4   ? 111.931 87.827  107.488 1.00 71.67  ? 4   PHE A CD2 1 
ATOM   29   C  CE1 . PHE A 1 4   ? 114.130 88.642  106.039 1.00 71.67  ? 4   PHE A CE1 1 
ATOM   30   C  CE2 . PHE A 1 4   ? 112.782 86.886  106.938 1.00 71.67  ? 4   PHE A CE2 1 
ATOM   31   C  CZ  . PHE A 1 4   ? 113.882 87.294  106.212 1.00 71.67  ? 4   PHE A CZ  1 
ATOM   32   N  N   . SER A 1 5   ? 109.690 91.758  110.235 1.00 61.98  ? 5   SER A N   1 
ATOM   33   C  CA  . SER A 1 5   ? 108.926 92.915  110.691 1.00 61.98  ? 5   SER A CA  1 
ATOM   34   C  C   . SER A 1 5   ? 109.615 93.603  111.864 1.00 61.98  ? 5   SER A C   1 
ATOM   35   O  O   . SER A 1 5   ? 109.667 94.838  111.928 1.00 61.98  ? 5   SER A O   1 
ATOM   36   C  CB  . SER A 1 5   ? 107.509 92.491  111.073 1.00 61.98  ? 5   SER A CB  1 
ATOM   37   O  OG  . SER A 1 5   ? 107.515 91.691  112.242 1.00 61.98  ? 5   SER A OG  1 
ATOM   38   N  N   . TYR A 1 6   ? 110.151 92.818  112.803 1.00 59.47  ? 6   TYR A N   1 
ATOM   39   C  CA  . TYR A 1 6   ? 110.840 93.399  113.950 1.00 59.47  ? 6   TYR A CA  1 
ATOM   40   C  C   . TYR A 1 6   ? 112.120 94.110  113.534 1.00 59.47  ? 6   TYR A C   1 
ATOM   41   O  O   . TYR A 1 6   ? 112.496 95.114  114.148 1.00 59.47  ? 6   TYR A O   1 
ATOM   42   C  CB  . TYR A 1 6   ? 111.144 92.318  114.987 1.00 59.47  ? 6   TYR A CB  1 
ATOM   43   C  CG  . TYR A 1 6   ? 109.943 91.896  115.804 1.00 59.47  ? 6   TYR A CG  1 
ATOM   44   C  CD1 . TYR A 1 6   ? 108.694 92.467  115.589 1.00 59.47  ? 6   TYR A CD1 1 
ATOM   45   C  CD2 . TYR A 1 6   ? 110.057 90.924  116.789 1.00 59.47  ? 6   TYR A CD2 1 
ATOM   46   C  CE1 . TYR A 1 6   ? 107.594 92.082  116.331 1.00 59.47  ? 6   TYR A CE1 1 
ATOM   47   C  CE2 . TYR A 1 6   ? 108.962 90.533  117.537 1.00 59.47  ? 6   TYR A CE2 1 
ATOM   48   C  CZ  . TYR A 1 6   ? 107.734 91.115  117.304 1.00 59.47  ? 6   TYR A CZ  1 
ATOM   49   O  OH  . TYR A 1 6   ? 106.642 90.728  118.047 1.00 59.47  ? 6   TYR A OH  1 
ATOM   50   N  N   . ILE A 1 7   ? 112.807 93.602  112.511 1.00 50.24  ? 7   ILE A N   1 
ATOM   51   C  CA  . ILE A 1 7   ? 113.959 94.317  111.973 1.00 50.24  ? 7   ILE A CA  1 
ATOM   52   C  C   . ILE A 1 7   ? 113.516 95.613  111.306 1.00 50.24  ? 7   ILE A C   1 
ATOM   53   O  O   . ILE A 1 7   ? 114.164 96.657  111.451 1.00 50.24  ? 7   ILE A O   1 
ATOM   54   C  CB  . ILE A 1 7   ? 114.740 93.416  111.000 1.00 50.24  ? 7   ILE A CB  1 
ATOM   55   C  CG1 . ILE A 1 7   ? 115.325 92.212  111.740 1.00 50.24  ? 7   ILE A CG1 1 
ATOM   56   C  CG2 . ILE A 1 7   ? 115.839 94.201  110.305 1.00 50.24  ? 7   ILE A CG2 1 
ATOM   57   C  CD1 . ILE A 1 7   ? 116.296 92.582  112.837 1.00 50.24  ? 7   ILE A CD1 1 
ATOM   58   N  N   . LEU A 1 8   ? 112.403 95.569  110.570 1.00 46.45  ? 8   LEU A N   1 
ATOM   59   C  CA  . LEU A 1 8   ? 111.942 96.745  109.839 1.00 46.45  ? 8   LEU A CA  1 
ATOM   60   C  C   . LEU A 1 8   ? 111.512 97.862  110.782 1.00 46.45  ? 8   LEU A C   1 
ATOM   61   O  O   . LEU A 1 8   ? 111.774 99.040  110.513 1.00 46.45  ? 8   LEU A O   1 
ATOM   62   C  CB  . LEU A 1 8   ? 110.795 96.363  108.905 1.00 46.45  ? 8   LEU A CB  1 
ATOM   63   C  CG  . LEU A 1 8   ? 110.065 97.518  108.215 1.00 46.45  ? 8   LEU A CG  1 
ATOM   64   C  CD1 . LEU A 1 8   ? 110.811 97.957  106.966 1.00 46.45  ? 8   LEU A CD1 1 
ATOM   65   C  CD2 . LEU A 1 8   ? 108.631 97.133  107.881 1.00 46.45  ? 8   LEU A CD2 1 
ATOM   66   N  N   . VAL A 1 9   ? 110.837 97.523  111.883 1.00 42.85  ? 9   VAL A N   1 
ATOM   67   C  CA  . VAL A 1 9   ? 110.373 98.569  112.791 1.00 42.85  ? 9   VAL A CA  1 
ATOM   68   C  C   . VAL A 1 9   ? 111.547 99.202  113.533 1.00 42.85  ? 9   VAL A C   1 
ATOM   69   O  O   . VAL A 1 9   ? 111.602 100.426 113.702 1.00 42.85  ? 9   VAL A O   1 
ATOM   70   C  CB  . VAL A 1 9   ? 109.305 98.019  113.756 1.00 42.85  ? 9   VAL A CB  1 
ATOM   71   C  CG1 . VAL A 1 9   ? 109.813 96.809  114.507 1.00 42.85  ? 9   VAL A CG1 1 
ATOM   72   C  CG2 . VAL A 1 9   ? 108.859 99.100  114.724 1.00 42.85  ? 9   VAL A CG2 1 
ATOM   73   N  N   . TYR A 1 10  ? 112.504 98.394  113.978 1.00 34.44  ? 10  TYR A N   1 
ATOM   74   C  CA  . TYR A 1 10  ? 113.665 98.895  114.715 1.00 34.44  ? 10  TYR A CA  1 
ATOM   75   C  C   . TYR A 1 10  ? 114.874 99.042  113.793 1.00 34.44  ? 10  TYR A C   1 
ATOM   76   O  O   . TYR A 1 10  ? 115.892 98.369  113.941 1.00 34.44  ? 10  TYR A O   1 
ATOM   77   C  CB  . TYR A 1 10  ? 113.976 97.976  115.893 1.00 34.44  ? 10  TYR A CB  1 
ATOM   78   C  CG  . TYR A 1 10  ? 112.808 97.765  116.826 1.00 34.44  ? 10  TYR A CG  1 
ATOM   79   C  CD1 . TYR A 1 10  ? 112.213 98.837  117.474 1.00 34.44  ? 10  TYR A CD1 1 
ATOM   80   C  CD2 . TYR A 1 10  ? 112.301 96.496  117.060 1.00 34.44  ? 10  TYR A CD2 1 
ATOM   81   C  CE1 . TYR A 1 10  ? 111.145 98.651  118.328 1.00 34.44  ? 10  TYR A CE1 1 
ATOM   82   C  CE2 . TYR A 1 10  ? 111.233 96.301  117.913 1.00 34.44  ? 10  TYR A CE2 1 
ATOM   83   C  CZ  . TYR A 1 10  ? 110.660 97.382  118.543 1.00 34.44  ? 10  TYR A CZ  1 
ATOM   84   O  OH  . TYR A 1 10  ? 109.596 97.195  119.394 1.00 34.44  ? 10  TYR A OH  1 
ATOM   85   N  N   . ARG A 1 11  ? 114.751 99.945  112.820 1.00 31.46  ? 11  ARG A N   1 
ATOM   86   C  CA  . ARG A 1 11  ? 115.856 100.182 111.896 1.00 31.46  ? 11  ARG A CA  1 
ATOM   87   C  C   . ARG A 1 11  ? 116.989 100.945 112.569 1.00 31.46  ? 11  ARG A C   1 
ATOM   88   O  O   . ARG A 1 11  ? 118.161 100.580 112.433 1.00 31.46  ? 11  ARG A O   1 
ATOM   89   C  CB  . ARG A 1 11  ? 115.362 100.943 110.667 1.00 31.46  ? 11  ARG A CB  1 
ATOM   90   C  CG  . ARG A 1 11  ? 114.584 100.101 109.682 1.00 31.46  ? 11  ARG A CG  1 
ATOM   91   C  CD  . ARG A 1 11  ? 113.987 100.961 108.584 1.00 31.46  ? 11  ARG A CD  1 
ATOM   92   N  NE  . ARG A 1 11  ? 113.414 102.194 109.108 1.00 31.46  ? 11  ARG A NE  1 
ATOM   93   C  CZ  . ARG A 1 11  ? 112.153 102.329 109.496 1.00 31.46  ? 11  ARG A CZ  1 
ATOM   94   N  NH1 . ARG A 1 11  ? 111.303 101.318 109.446 1.00 31.46  ? 11  ARG A NH1 1 
ATOM   95   N  NH2 . ARG A 1 11  ? 111.735 103.509 109.945 1.00 31.46  ? 11  ARG A NH2 1 
ATOM   96   N  N   . ARG A 1 12  ? 116.657 102.005 113.307 1.00 25.25  ? 12  ARG A N   1 
ATOM   97   C  CA  . ARG A 1 12  ? 117.687 102.911 113.808 1.00 25.25  ? 12  ARG A CA  1 
ATOM   98   C  C   . ARG A 1 12  ? 118.520 102.261 114.905 1.00 25.25  ? 12  ARG A C   1 
ATOM   99   O  O   . ARG A 1 12  ? 119.750 102.379 114.912 1.00 25.25  ? 12  ARG A O   1 
ATOM   100  C  CB  . ARG A 1 12  ? 117.047 104.203 114.310 1.00 25.25  ? 12  ARG A CB  1 
ATOM   101  C  CG  . ARG A 1 12  ? 116.464 105.067 113.209 1.00 25.25  ? 12  ARG A CG  1 
ATOM   102  C  CD  . ARG A 1 12  ? 116.066 106.434 113.735 1.00 25.25  ? 12  ARG A CD  1 
ATOM   103  N  NE  . ARG A 1 12  ? 115.359 106.349 115.007 1.00 25.25  ? 12  ARG A NE  1 
ATOM   104  C  CZ  . ARG A 1 12  ? 114.135 105.860 115.160 1.00 25.25  ? 12  ARG A CZ  1 
ATOM   105  N  NH1 . ARG A 1 12  ? 113.436 105.408 114.132 1.00 25.25  ? 12  ARG A NH1 1 
ATOM   106  N  NH2 . ARG A 1 12  ? 113.599 105.826 116.376 1.00 25.25  ? 12  ARG A NH2 1 
ATOM   107  N  N   . PHE A 1 13  ? 117.868 101.579 115.847 1.00 20.07  ? 13  PHE A N   1 
ATOM   108  C  CA  . PHE A 1 13  ? 118.595 100.936 116.938 1.00 20.07  ? 13  PHE A CA  1 
ATOM   109  C  C   . PHE A 1 13  ? 119.538 99.863  116.407 1.00 20.07  ? 13  PHE A C   1 
ATOM   110  O  O   . PHE A 1 13  ? 120.725 99.820  116.766 1.00 20.07  ? 13  PHE A O   1 
ATOM   111  C  CB  . PHE A 1 13  ? 117.597 100.345 117.934 1.00 20.07  ? 13  PHE A CB  1 
ATOM   112  C  CG  . PHE A 1 13  ? 118.232 99.677  119.116 1.00 20.07  ? 13  PHE A CG  1 
ATOM   113  C  CD1 . PHE A 1 13  ? 118.714 100.425 120.175 1.00 20.07  ? 13  PHE A CD1 1 
ATOM   114  C  CD2 . PHE A 1 13  ? 118.332 98.299  119.177 1.00 20.07  ? 13  PHE A CD2 1 
ATOM   115  C  CE1 . PHE A 1 13  ? 119.293 99.811  121.266 1.00 20.07  ? 13  PHE A CE1 1 
ATOM   116  C  CE2 . PHE A 1 13  ? 118.912 97.681  120.265 1.00 20.07  ? 13  PHE A CE2 1 
ATOM   117  C  CZ  . PHE A 1 13  ? 119.393 98.439  121.310 1.00 20.07  ? 13  PHE A CZ  1 
ATOM   118  N  N   . LEU A 1 14  ? 119.025 98.994  115.533 1.00 21.06  ? 14  LEU A N   1 
ATOM   119  C  CA  . LEU A 1 14  ? 119.854 97.946  114.951 1.00 21.06  ? 14  LEU A CA  1 
ATOM   120  C  C   . LEU A 1 14  ? 120.993 98.535  114.134 1.00 21.06  ? 14  LEU A C   1 
ATOM   121  O  O   . LEU A 1 14  ? 122.123 98.043  114.196 1.00 21.06  ? 14  LEU A O   1 
ATOM   122  C  CB  . LEU A 1 14  ? 119.003 97.011  114.090 1.00 21.06  ? 14  LEU A CB  1 
ATOM   123  C  CG  . LEU A 1 14  ? 118.299 95.829  114.764 1.00 21.06  ? 14  LEU A CG  1 
ATOM   124  C  CD1 . LEU A 1 14  ? 119.326 94.859  115.319 1.00 21.06  ? 14  LEU A CD1 1 
ATOM   125  C  CD2 . LEU A 1 14  ? 117.345 96.274  115.860 1.00 21.06  ? 14  LEU A CD2 1 
ATOM   126  N  N   . PHE A 1 15  ? 120.718 99.590  113.364 1.00 18.80  ? 15  PHE A N   1 
ATOM   127  C  CA  . PHE A 1 15  ? 121.770 100.201 112.559 1.00 18.80  ? 15  PHE A CA  1 
ATOM   128  C  C   . PHE A 1 15  ? 122.858 100.809 113.433 1.00 18.80  ? 15  PHE A C   1 
ATOM   129  O  O   . PHE A 1 15  ? 124.048 100.669 113.136 1.00 18.80  ? 15  PHE A O   1 
ATOM   130  C  CB  . PHE A 1 15  ? 121.183 101.261 111.631 1.00 18.80  ? 15  PHE A CB  1 
ATOM   131  C  CG  . PHE A 1 15  ? 122.194 101.880 110.715 1.00 18.80  ? 15  PHE A CG  1 
ATOM   132  C  CD1 . PHE A 1 15  ? 122.694 101.172 109.637 1.00 18.80  ? 15  PHE A CD1 1 
ATOM   133  C  CD2 . PHE A 1 15  ? 122.654 103.165 110.937 1.00 18.80  ? 15  PHE A CD2 1 
ATOM   134  C  CE1 . PHE A 1 15  ? 123.629 101.737 108.794 1.00 18.80  ? 15  PHE A CE1 1 
ATOM   135  C  CE2 . PHE A 1 15  ? 123.589 103.734 110.097 1.00 18.80  ? 15  PHE A CE2 1 
ATOM   136  C  CZ  . PHE A 1 15  ? 124.076 103.020 109.024 1.00 18.80  ? 15  PHE A CZ  1 
ATOM   137  N  N   . VAL A 1 16  ? 122.473 101.494 114.511 1.00 17.48  ? 16  VAL A N   1 
ATOM   138  C  CA  . VAL A 1 16  ? 123.462 102.106 115.395 1.00 17.48  ? 16  VAL A CA  1 
ATOM   139  C  C   . VAL A 1 16  ? 124.337 101.033 116.029 1.00 17.48  ? 16  VAL A C   1 
ATOM   140  O  O   . VAL A 1 16  ? 125.571 101.137 116.040 1.00 17.48  ? 16  VAL A O   1 
ATOM   141  C  CB  . VAL A 1 16  ? 122.770 102.972 116.461 1.00 17.48  ? 16  VAL A CB  1 
ATOM   142  C  CG1 . VAL A 1 16  ? 123.740 103.316 117.576 1.00 17.48  ? 16  VAL A CG1 1 
ATOM   143  C  CG2 . VAL A 1 16  ? 122.211 104.235 115.835 1.00 17.48  ? 16  VAL A CG2 1 
ATOM   144  N  N   . VAL A 1 17  ? 123.710 99.974  116.547 1.00 18.96  ? 17  VAL A N   1 
ATOM   145  C  CA  . VAL A 1 17  ? 124.480 98.903  117.175 1.00 18.96  ? 17  VAL A CA  1 
ATOM   146  C  C   . VAL A 1 17  ? 125.400 98.239  116.157 1.00 18.96  ? 17  VAL A C   1 
ATOM   147  O  O   . VAL A 1 17  ? 126.574 97.965  116.442 1.00 18.96  ? 17  VAL A O   1 
ATOM   148  C  CB  . VAL A 1 17  ? 123.536 97.886  117.840 1.00 18.96  ? 17  VAL A CB  1 
ATOM   149  C  CG1 . VAL A 1 17  ? 124.326 96.716  118.394 1.00 18.96  ? 17  VAL A CG1 1 
ATOM   150  C  CG2 . VAL A 1 17  ? 122.739 98.556  118.943 1.00 18.96  ? 17  VAL A CG2 1 
ATOM   151  N  N   . PHE A 1 18  ? 124.889 97.981  114.951 1.00 22.25  ? 18  PHE A N   1 
ATOM   152  C  CA  . PHE A 1 18  ? 125.683 97.313  113.928 1.00 22.25  ? 18  PHE A CA  1 
ATOM   153  C  C   . PHE A 1 18  ? 126.873 98.163  113.508 1.00 22.25  ? 18  PHE A C   1 
ATOM   154  O  O   . PHE A 1 18  ? 127.981 97.647  113.339 1.00 22.25  ? 18  PHE A O   1 
ATOM   155  C  CB  . PHE A 1 18  ? 124.806 96.982  112.721 1.00 22.25  ? 18  PHE A CB  1 
ATOM   156  C  CG  . PHE A 1 18  ? 125.580 96.529  111.518 1.00 22.25  ? 18  PHE A CG  1 
ATOM   157  C  CD1 . PHE A 1 18  ? 126.130 95.260  111.470 1.00 22.25  ? 18  PHE A CD1 1 
ATOM   158  C  CD2 . PHE A 1 18  ? 125.758 97.372  110.434 1.00 22.25  ? 18  PHE A CD2 1 
ATOM   159  C  CE1 . PHE A 1 18  ? 126.843 94.841  110.365 1.00 22.25  ? 18  PHE A CE1 1 
ATOM   160  C  CE2 . PHE A 1 18  ? 126.470 96.958  109.327 1.00 22.25  ? 18  PHE A CE2 1 
ATOM   161  C  CZ  . PHE A 1 18  ? 127.013 95.691  109.292 1.00 22.25  ? 18  PHE A CZ  1 
ATOM   162  N  N   . THR A 1 19  ? 126.665 99.468  113.321 1.00 18.74  ? 19  THR A N   1 
ATOM   163  C  CA  . THR A 1 19  ? 127.770 100.332 112.917 1.00 18.74  ? 19  THR A CA  1 
ATOM   164  C  C   . THR A 1 19  ? 128.807 100.453 114.023 1.00 18.74  ? 19  THR A C   1 
ATOM   165  O  O   . THR A 1 19  ? 130.011 100.509 113.749 1.00 18.74  ? 19  THR A O   1 
ATOM   166  C  CB  . THR A 1 19  ? 127.258 101.714 112.517 1.00 18.74  ? 19  THR A CB  1 
ATOM   167  O  OG1 . THR A 1 19  ? 126.430 102.239 113.560 1.00 18.74  ? 19  THR A OG1 1 
ATOM   168  C  CG2 . THR A 1 19  ? 126.464 101.631 111.231 1.00 18.74  ? 19  THR A CG2 1 
ATOM   169  N  N   . VAL A 1 20  ? 128.363 100.505 115.281 1.00 17.68  ? 20  VAL A N   1 
ATOM   170  C  CA  . VAL A 1 20  ? 129.317 100.552 116.384 1.00 17.68  ? 20  VAL A CA  1 
ATOM   171  C  C   . VAL A 1 20  ? 130.146 99.274  116.426 1.00 17.68  ? 20  VAL A C   1 
ATOM   172  O  O   . VAL A 1 20  ? 131.368 99.315  116.616 1.00 17.68  ? 20  VAL A O   1 
ATOM   173  C  CB  . VAL A 1 20  ? 128.586 100.804 117.716 1.00 17.68  ? 20  VAL A CB  1 
ATOM   174  C  CG1 . VAL A 1 20  ? 129.490 100.479 118.890 1.00 17.68  ? 20  VAL A CG1 1 
ATOM   175  C  CG2 . VAL A 1 20  ? 128.119 102.244 117.795 1.00 17.68  ? 20  VAL A CG2 1 
ATOM   176  N  N   . LEU A 1 21  ? 129.501 98.120  116.237 1.00 21.49  ? 21  LEU A N   1 
ATOM   177  C  CA  . LEU A 1 21  ? 130.207 96.848  116.368 1.00 21.49  ? 21  LEU A CA  1 
ATOM   178  C  C   . LEU A 1 21  ? 131.110 96.547  115.174 1.00 21.49  ? 21  LEU A C   1 
ATOM   179  O  O   . LEU A 1 21  ? 132.225 96.046  115.353 1.00 21.49  ? 21  LEU A O   1 
ATOM   180  C  CB  . LEU A 1 21  ? 129.205 95.711  116.567 1.00 21.49  ? 21  LEU A CB  1 
ATOM   181  C  CG  . LEU A 1 21  ? 128.435 95.718  117.887 1.00 21.49  ? 21  LEU A CG  1 
ATOM   182  C  CD1 . LEU A 1 21  ? 127.766 94.375  118.119 1.00 21.49  ? 21  LEU A CD1 1 
ATOM   183  C  CD2 . LEU A 1 21  ? 129.355 96.068  119.044 1.00 21.49  ? 21  LEU A CD2 1 
ATOM   184  N  N   . VAL A 1 22  ? 130.654 96.835  113.953 1.00 23.19  ? 22  VAL A N   1 
ATOM   185  C  CA  . VAL A 1 22  ? 131.377 96.379  112.769 1.00 23.19  ? 22  VAL A CA  1 
ATOM   186  C  C   . VAL A 1 22  ? 132.696 97.124  112.600 1.00 23.19  ? 22  VAL A C   1 
ATOM   187  O  O   . VAL A 1 22  ? 133.656 96.573  112.051 1.00 23.19  ? 22  VAL A O   1 
ATOM   188  C  CB  . VAL A 1 22  ? 130.498 96.511  111.511 1.00 23.19  ? 22  VAL A CB  1 
ATOM   189  C  CG1 . VAL A 1 22  ? 130.191 97.970  111.212 1.00 23.19  ? 22  VAL A CG1 1 
ATOM   190  C  CG2 . VAL A 1 22  ? 131.157 95.837  110.318 1.00 23.19  ? 22  VAL A CG2 1 
ATOM   191  N  N   . LEU A 1 23  ? 132.772 98.373  113.050 1.00 22.48  ? 23  LEU A N   1 
ATOM   192  C  CA  . LEU A 1 23  ? 133.989 99.159  112.917 1.00 22.48  ? 23  LEU A CA  1 
ATOM   193  C  C   . LEU A 1 23  ? 134.943 98.982  114.091 1.00 22.48  ? 23  LEU A C   1 
ATOM   194  O  O   . LEU A 1 23  ? 136.060 99.506  114.044 1.00 22.48  ? 23  LEU A O   1 
ATOM   195  C  CB  . LEU A 1 23  ? 133.639 100.640 112.751 1.00 22.48  ? 23  LEU A CB  1 
ATOM   196  C  CG  . LEU A 1 23  ? 132.721 100.962 111.572 1.00 22.48  ? 23  LEU A CG  1 
ATOM   197  C  CD1 . LEU A 1 23  ? 132.366 102.437 111.546 1.00 22.48  ? 23  LEU A CD1 1 
ATOM   198  C  CD2 . LEU A 1 23  ? 133.372 100.543 110.268 1.00 22.48  ? 23  LEU A CD2 1 
ATOM   199  N  N   . LEU A 1 24  ? 134.533 98.263  115.132 1.00 22.92  ? 24  LEU A N   1 
ATOM   200  C  CA  . LEU A 1 24  ? 135.363 97.957  116.294 1.00 22.92  ? 24  LEU A CA  1 
ATOM   201  C  C   . LEU A 1 24  ? 136.604 97.135  115.945 1.00 22.92  ? 24  LEU A C   1 
ATOM   202  O  O   . LEU A 1 24  ? 137.630 97.267  116.629 1.00 22.92  ? 24  LEU A O   1 
ATOM   203  C  CB  . LEU A 1 24  ? 134.532 97.225  117.351 1.00 22.92  ? 24  LEU A CB  1 
ATOM   204  C  CG  . LEU A 1 24  ? 134.876 97.487  118.817 1.00 22.92  ? 24  LEU A CG  1 
ATOM   205  C  CD1 . LEU A 1 24  ? 134.932 98.977  119.100 1.00 22.92  ? 24  LEU A CD1 1 
ATOM   206  C  CD2 . LEU A 1 24  ? 133.863 96.808  119.719 1.00 22.92  ? 24  LEU A CD2 1 
ATOM   207  N  N   . PRO A 1 25  ? 136.559 96.257  114.929 1.00 23.83  ? 25  PRO A N   1 
ATOM   208  C  CA  . PRO A 1 25  ? 137.795 95.570  114.524 1.00 23.83  ? 25  PRO A CA  1 
ATOM   209  C  C   . PRO A 1 25  ? 138.966 96.494  114.247 1.00 23.83  ? 25  PRO A C   1 
ATOM   210  O  O   . PRO A 1 25  ? 140.105 96.119  114.540 1.00 23.83  ? 25  PRO A O   1 
ATOM   211  C  CB  . PRO A 1 25  ? 137.365 94.816  113.262 1.00 23.83  ? 25  PRO A CB  1 
ATOM   212  C  CG  . PRO A 1 25  ? 135.942 94.498  113.493 1.00 23.83  ? 25  PRO A CG  1 
ATOM   213  C  CD  . PRO A 1 25  ? 135.375 95.520  114.448 1.00 23.83  ? 25  PRO A CD  1 
ATOM   214  N  N   . LEU A 1 26  ? 138.734 97.687  113.695 1.00 23.13  ? 26  LEU A N   1 
ATOM   215  C  CA  . LEU A 1 26  ? 139.853 98.582  113.403 1.00 23.13  ? 26  LEU A CA  1 
ATOM   216  C  C   . LEU A 1 26  ? 140.615 98.983  114.664 1.00 23.13  ? 26  LEU A C   1 
ATOM   217  O  O   . LEU A 1 26  ? 141.833 98.739  114.729 1.00 23.13  ? 26  LEU A O   1 
ATOM   218  C  CB  . LEU A 1 26  ? 139.342 99.786  112.604 1.00 23.13  ? 26  LEU A CB  1 
ATOM   219  C  CG  . LEU A 1 26  ? 140.366 100.759 112.023 1.00 23.13  ? 26  LEU A CG  1 
ATOM   220  C  CD1 . LEU A 1 26  ? 141.131 100.116 110.880 1.00 23.13  ? 26  LEU A CD1 1 
ATOM   221  C  CD2 . LEU A 1 26  ? 139.672 102.026 111.556 1.00 23.13  ? 26  LEU A CD2 1 
ATOM   222  N  N   . PRO A 1 27  ? 139.987 99.565  115.696 1.00 22.16  ? 27  PRO A N   1 
ATOM   223  C  CA  . PRO A 1 27  ? 140.738 99.812  116.937 1.00 22.16  ? 27  PRO A CA  1 
ATOM   224  C  C   . PRO A 1 27  ? 141.209 98.545  117.625 1.00 22.16  ? 27  PRO A C   1 
ATOM   225  O  O   . PRO A 1 27  ? 142.290 98.548  118.226 1.00 22.16  ? 27  PRO A O   1 
ATOM   226  C  CB  . PRO A 1 27  ? 139.738 100.581 117.812 1.00 22.16  ? 27  PRO A CB  1 
ATOM   227  C  CG  . PRO A 1 27  ? 138.736 101.115 116.876 1.00 22.16  ? 27  PRO A CG  1 
ATOM   228  C  CD  . PRO A 1 27  ? 138.617 100.097 115.798 1.00 22.16  ? 27  PRO A CD  1 
ATOM   229  N  N   . ILE A 1 28  ? 140.430 97.461  117.565 1.00 24.06  ? 28  ILE A N   1 
ATOM   230  C  CA  . ILE A 1 28  ? 140.804 96.256  118.299 1.00 24.06  ? 28  ILE A CA  1 
ATOM   231  C  C   . ILE A 1 28  ? 142.064 95.624  117.718 1.00 24.06  ? 28  ILE A C   1 
ATOM   232  O  O   . ILE A 1 28  ? 142.901 95.098  118.461 1.00 24.06  ? 28  ILE A O   1 
ATOM   233  C  CB  . ILE A 1 28  ? 139.624 95.267  118.328 1.00 24.06  ? 28  ILE A CB  1 
ATOM   234  C  CG1 . ILE A 1 28  ? 138.523 95.795  119.247 1.00 24.06  ? 28  ILE A CG1 1 
ATOM   235  C  CG2 . ILE A 1 28  ? 140.075 93.890  118.787 1.00 24.06  ? 28  ILE A CG2 1 
ATOM   236  C  CD1 . ILE A 1 28  ? 138.887 95.768  120.712 1.00 24.06  ? 28  ILE A CD1 1 
ATOM   237  N  N   . VAL A 1 29  ? 142.236 95.675  116.401 1.00 26.30  ? 29  VAL A N   1 
ATOM   238  C  CA  . VAL A 1 29  ? 143.372 95.028  115.754 1.00 26.30  ? 29  VAL A CA  1 
ATOM   239  C  C   . VAL A 1 29  ? 144.551 95.979  115.613 1.00 26.30  ? 29  VAL A C   1 
ATOM   240  O  O   . VAL A 1 29  ? 145.689 95.619  115.926 1.00 26.30  ? 29  VAL A O   1 
ATOM   241  C  CB  . VAL A 1 29  ? 142.940 94.461  114.385 1.00 26.30  ? 29  VAL A CB  1 
ATOM   242  C  CG1 . VAL A 1 29  ? 144.150 93.987  113.601 1.00 26.30  ? 29  VAL A CG1 1 
ATOM   243  C  CG2 . VAL A 1 29  ? 141.948 93.329  114.573 1.00 26.30  ? 29  VAL A CG2 1 
ATOM   244  N  N   . LEU A 1 30  ? 144.311 97.206  115.144 1.00 26.60  ? 30  LEU A N   1 
ATOM   245  C  CA  . LEU A 1 30  ? 145.427 98.093  114.831 1.00 26.60  ? 30  LEU A CA  1 
ATOM   246  C  C   . LEU A 1 30  ? 146.142 98.586  116.084 1.00 26.60  ? 30  LEU A C   1 
ATOM   247  O  O   . LEU A 1 30  ? 147.367 98.758  116.064 1.00 26.60  ? 30  LEU A O   1 
ATOM   248  C  CB  . LEU A 1 30  ? 144.941 99.272  113.991 1.00 26.60  ? 30  LEU A CB  1 
ATOM   249  C  CG  . LEU A 1 30  ? 144.972 99.086  112.471 1.00 26.60  ? 30  LEU A CG  1 
ATOM   250  C  CD1 . LEU A 1 30  ? 146.397 98.858  111.995 1.00 26.60  ? 30  LEU A CD1 1 
ATOM   251  C  CD2 . LEU A 1 30  ? 144.069 97.949  112.025 1.00 26.60  ? 30  LEU A CD2 1 
ATOM   252  N  N   . HIS A 1 31  ? 145.406 98.818  117.174 1.00 29.97  ? 31  HIS A N   1 
ATOM   253  C  CA  . HIS A 1 31  ? 145.982 99.272  118.444 1.00 29.97  ? 31  HIS A CA  1 
ATOM   254  C  C   . HIS A 1 31  ? 146.775 100.566 118.276 1.00 29.97  ? 31  HIS A C   1 
ATOM   255  O  O   . HIS A 1 31  ? 147.838 100.742 118.874 1.00 29.97  ? 31  HIS A O   1 
ATOM   256  C  CB  . HIS A 1 31  ? 146.865 98.195  119.079 1.00 29.97  ? 31  HIS A CB  1 
ATOM   257  C  CG  . HIS A 1 31  ? 146.197 96.865  119.229 1.00 29.97  ? 31  HIS A CG  1 
ATOM   258  N  ND1 . HIS A 1 31  ? 146.646 95.731  118.586 1.00 29.97  ? 31  HIS A ND1 1 
ATOM   259  C  CD2 . HIS A 1 31  ? 145.123 96.483  119.958 1.00 29.97  ? 31  HIS A CD2 1 
ATOM   260  C  CE1 . HIS A 1 31  ? 145.873 94.710  118.908 1.00 29.97  ? 31  HIS A CE1 1 
ATOM   261  N  NE2 . HIS A 1 31  ? 144.940 95.139  119.738 1.00 29.97  ? 31  HIS A NE2 1 
ATOM   262  N  N   . THR A 1 32  ? 146.263 101.483 117.459 1.00 26.77  ? 32  THR A N   1 
ATOM   263  C  CA  . THR A 1 32  ? 146.929 102.754 117.222 1.00 26.77  ? 32  THR A CA  1 
ATOM   264  C  C   . THR A 1 32  ? 145.948 103.898 117.426 1.00 26.77  ? 32  THR A C   1 
ATOM   265  O  O   . THR A 1 32  ? 144.741 103.747 117.220 1.00 26.77  ? 32  THR A O   1 
ATOM   266  C  CB  . THR A 1 32  ? 147.527 102.836 115.810 1.00 26.77  ? 32  THR A CB  1 
ATOM   267  O  OG1 . THR A 1 32  ? 146.503 102.594 114.839 1.00 26.77  ? 32  THR A OG1 1 
ATOM   268  C  CG2 . THR A 1 32  ? 148.637 101.812 115.637 1.00 26.77  ? 32  THR A CG2 1 
ATOM   269  N  N   . LYS A 1 33  ? 146.485 105.049 117.838 1.00 21.68  ? 33  LYS A N   1 
ATOM   270  C  CA  . LYS A 1 33  ? 145.647 106.225 118.044 1.00 21.68  ? 33  LYS A CA  1 
ATOM   271  C  C   . LYS A 1 33  ? 145.031 106.698 116.734 1.00 21.68  ? 33  LYS A C   1 
ATOM   272  O  O   . LYS A 1 33  ? 143.897 107.191 116.713 1.00 21.68  ? 33  LYS A O   1 
ATOM   273  C  CB  . LYS A 1 33  ? 146.463 107.342 118.691 1.00 21.68  ? 33  LYS A CB  1 
ATOM   274  C  CG  . LYS A 1 33  ? 146.813 107.084 120.143 1.00 21.68  ? 33  LYS A CG  1 
ATOM   275  C  CD  . LYS A 1 33  ? 145.613 107.310 121.041 1.00 21.68  ? 33  LYS A CD  1 
ATOM   276  C  CE  . LYS A 1 33  ? 145.824 106.693 122.411 1.00 21.68  ? 33  LYS A CE  1 
ATOM   277  N  NZ  . LYS A 1 33  ? 145.782 105.207 122.363 1.00 21.68  ? 33  LYS A NZ  1 
ATOM   278  N  N   . GLU A 1 34  ? 145.769 106.563 115.629 1.00 25.72  ? 34  GLU A N   1 
ATOM   279  C  CA  . GLU A 1 34  ? 145.219 106.931 114.330 1.00 25.72  ? 34  GLU A CA  1 
ATOM   280  C  C   . GLU A 1 34  ? 144.005 106.080 113.990 1.00 25.72  ? 34  GLU A C   1 
ATOM   281  O  O   . GLU A 1 34  ? 142.998 106.595 113.494 1.00 25.72  ? 34  GLU A O   1 
ATOM   282  C  CB  . GLU A 1 34  ? 146.286 106.793 113.245 1.00 25.72  ? 34  GLU A CB  1 
ATOM   283  C  CG  . GLU A 1 34  ? 147.431 107.779 113.362 1.00 25.72  ? 34  GLU A CG  1 
ATOM   284  C  CD  . GLU A 1 34  ? 148.591 107.230 114.162 1.00 25.72  ? 34  GLU A CD  1 
ATOM   285  O  OE1 . GLU A 1 34  ? 148.524 106.053 114.574 1.00 25.72  ? 34  GLU A OE1 1 
ATOM   286  O  OE2 . GLU A 1 34  ? 149.572 107.971 114.376 1.00 25.72  ? 34  GLU A OE2 1 
ATOM   287  N  N   . ALA A 1 35  ? 144.078 104.774 114.259 1.00 20.87  ? 35  ALA A N   1 
ATOM   288  C  CA  . ALA A 1 35  ? 142.942 103.900 113.987 1.00 20.87  ? 35  ALA A CA  1 
ATOM   289  C  C   . ALA A 1 35  ? 141.745 104.256 114.858 1.00 20.87  ? 35  ALA A C   1 
ATOM   290  O  O   . ALA A 1 35  ? 140.603 104.234 114.390 1.00 20.87  ? 35  ALA A O   1 
ATOM   291  C  CB  . ALA A 1 35  ? 143.338 102.441 114.197 1.00 20.87  ? 35  ALA A CB  1 
ATOM   292  N  N   . GLU A 1 36  ? 141.983 104.575 116.131 1.00 20.55  ? 36  GLU A N   1 
ATOM   293  C  CA  . GLU A 1 36  ? 140.881 104.939 117.016 1.00 20.55  ? 36  GLU A CA  1 
ATOM   294  C  C   . GLU A 1 36  ? 140.218 106.239 116.573 1.00 20.55  ? 36  GLU A C   1 
ATOM   295  O  O   . GLU A 1 36  ? 138.984 106.347 116.571 1.00 20.55  ? 36  GLU A O   1 
ATOM   296  C  CB  . GLU A 1 36  ? 141.386 105.044 118.453 1.00 20.55  ? 36  GLU A CB  1 
ATOM   297  C  CG  . GLU A 1 36  ? 141.996 103.752 118.970 1.00 20.55  ? 36  GLU A CG  1 
ATOM   298  C  CD  . GLU A 1 36  ? 142.820 103.952 120.223 1.00 20.55  ? 36  GLU A CD  1 
ATOM   299  O  OE1 . GLU A 1 36  ? 142.815 105.075 120.765 1.00 20.55  ? 36  GLU A OE1 1 
ATOM   300  O  OE2 . GLU A 1 36  ? 143.476 102.986 120.665 1.00 20.55  ? 36  GLU A OE2 1 
ATOM   301  N  N   . CYS A 1 37  ? 141.018 107.235 116.189 1.00 19.06  ? 37  CYS A N   1 
ATOM   302  C  CA  . CYS A 1 37  ? 140.441 108.478 115.691 1.00 19.06  ? 37  CYS A CA  1 
ATOM   303  C  C   . CYS A 1 37  ? 139.699 108.256 114.379 1.00 19.06  ? 37  CYS A C   1 
ATOM   304  O  O   . CYS A 1 37  ? 138.653 108.869 114.143 1.00 19.06  ? 37  CYS A O   1 
ATOM   305  C  CB  . CYS A 1 37  ? 141.524 109.537 115.520 1.00 19.06  ? 37  CYS A CB  1 
ATOM   306  S  SG  . CYS A 1 37  ? 140.876 111.136 115.005 1.00 19.06  ? 37  CYS A SG  1 
ATOM   307  N  N   . ALA A 1 38  ? 140.226 107.391 113.510 1.00 18.85  ? 38  ALA A N   1 
ATOM   308  C  CA  . ALA A 1 38  ? 139.525 107.067 112.273 1.00 18.85  ? 38  ALA A CA  1 
ATOM   309  C  C   . ALA A 1 38  ? 138.198 106.381 112.558 1.00 18.85  ? 38  ALA A C   1 
ATOM   310  O  O   . ALA A 1 38  ? 137.201 106.635 111.875 1.00 18.85  ? 38  ALA A O   1 
ATOM   311  C  CB  . ALA A 1 38  ? 140.404 106.187 111.387 1.00 18.85  ? 38  ALA A CB  1 
ATOM   312  N  N   . TYR A 1 39  ? 138.171 105.498 113.555 1.00 16.97  ? 39  TYR A N   1 
ATOM   313  C  CA  . TYR A 1 39  ? 136.929 104.837 113.942 1.00 16.97  ? 39  TYR A CA  1 
ATOM   314  C  C   . TYR A 1 39  ? 135.909 105.847 114.447 1.00 16.97  ? 39  TYR A C   1 
ATOM   315  O  O   . TYR A 1 39  ? 134.727 105.791 114.085 1.00 16.97  ? 39  TYR A O   1 
ATOM   316  C  CB  . TYR A 1 39  ? 137.223 103.779 115.005 1.00 16.97  ? 39  TYR A CB  1 
ATOM   317  C  CG  . TYR A 1 39  ? 136.021 103.343 115.808 1.00 16.97  ? 39  TYR A CG  1 
ATOM   318  C  CD1 . TYR A 1 39  ? 135.126 102.413 115.304 1.00 16.97  ? 39  TYR A CD1 1 
ATOM   319  C  CD2 . TYR A 1 39  ? 135.787 103.852 117.076 1.00 16.97  ? 39  TYR A CD2 1 
ATOM   320  C  CE1 . TYR A 1 39  ? 134.029 102.009 116.034 1.00 16.97  ? 39  TYR A CE1 1 
ATOM   321  C  CE2 . TYR A 1 39  ? 134.692 103.453 117.814 1.00 16.97  ? 39  TYR A CE2 1 
ATOM   322  C  CZ  . TYR A 1 39  ? 133.817 102.533 117.287 1.00 16.97  ? 39  TYR A CZ  1 
ATOM   323  O  OH  . TYR A 1 39  ? 132.726 102.133 118.019 1.00 16.97  ? 39  TYR A OH  1 
ATOM   324  N  N   . THR A 1 40  ? 136.352 106.785 115.288 1.00 15.49  ? 40  THR A N   1 
ATOM   325  C  CA  . THR A 1 40  ? 135.451 107.833 115.760 1.00 15.49  ? 40  THR A CA  1 
ATOM   326  C  C   . THR A 1 40  ? 134.927 108.670 114.599 1.00 15.49  ? 40  THR A C   1 
ATOM   327  O  O   . THR A 1 40  ? 133.731 108.983 114.536 1.00 15.49  ? 40  THR A O   1 
ATOM   328  C  CB  . THR A 1 40  ? 136.163 108.726 116.774 1.00 15.49  ? 40  THR A CB  1 
ATOM   329  O  OG1 . THR A 1 40  ? 136.782 107.914 117.777 1.00 15.49  ? 40  THR A OG1 1 
ATOM   330  C  CG2 . THR A 1 40  ? 135.176 109.671 117.433 1.00 15.49  ? 40  THR A CG2 1 
ATOM   331  N  N   . LEU A 1 41  ? 135.811 109.031 113.667 1.00 17.54  ? 41  LEU A N   1 
ATOM   332  C  CA  . LEU A 1 41  ? 135.403 109.810 112.503 1.00 17.54  ? 41  LEU A CA  1 
ATOM   333  C  C   . LEU A 1 41  ? 134.372 109.060 111.671 1.00 17.54  ? 41  LEU A C   1 
ATOM   334  O  O   . LEU A 1 41  ? 133.366 109.639 111.247 1.00 17.54  ? 41  LEU A O   1 
ATOM   335  C  CB  . LEU A 1 41  ? 136.631 110.150 111.658 1.00 17.54  ? 41  LEU A CB  1 
ATOM   336  C  CG  . LEU A 1 41  ? 136.567 111.361 110.730 1.00 17.54  ? 41  LEU A CG  1 
ATOM   337  C  CD1 . LEU A 1 41  ? 136.600 112.646 111.528 1.00 17.54  ? 41  LEU A CD1 1 
ATOM   338  C  CD2 . LEU A 1 41  ? 137.714 111.321 109.737 1.00 17.54  ? 41  LEU A CD2 1 
ATOM   339  N  N   . PHE A 1 42  ? 134.605 107.768 111.431 1.00 20.80  ? 42  PHE A N   1 
ATOM   340  C  CA  . PHE A 1 42  ? 133.676 106.978 110.633 1.00 20.80  ? 42  PHE A CA  1 
ATOM   341  C  C   . PHE A 1 42  ? 132.324 106.856 111.317 1.00 20.80  ? 42  PHE A C   1 
ATOM   342  O  O   . PHE A 1 42  ? 131.282 106.971 110.665 1.00 20.80  ? 42  PHE A O   1 
ATOM   343  C  CB  . PHE A 1 42  ? 134.259 105.592 110.360 1.00 20.80  ? 42  PHE A CB  1 
ATOM   344  C  CG  . PHE A 1 42  ? 135.445 105.603 109.441 1.00 20.80  ? 42  PHE A CG  1 
ATOM   345  C  CD1 . PHE A 1 42  ? 135.661 106.663 108.578 1.00 20.80  ? 42  PHE A CD1 1 
ATOM   346  C  CD2 . PHE A 1 42  ? 136.342 104.550 109.436 1.00 20.80  ? 42  PHE A CD2 1 
ATOM   347  C  CE1 . PHE A 1 42  ? 136.751 106.676 107.732 1.00 20.80  ? 42  PHE A CE1 1 
ATOM   348  C  CE2 . PHE A 1 42  ? 137.432 104.557 108.591 1.00 20.80  ? 42  PHE A CE2 1 
ATOM   349  C  CZ  . PHE A 1 42  ? 137.636 105.621 107.739 1.00 20.80  ? 42  PHE A CZ  1 
ATOM   350  N  N   . VAL A 1 43  ? 132.318 106.623 112.631 1.00 14.03  ? 43  VAL A N   1 
ATOM   351  C  CA  . VAL A 1 43  ? 131.054 106.491 113.353 1.00 14.03  ? 43  VAL A CA  1 
ATOM   352  C  C   . VAL A 1 43  ? 130.270 107.797 113.300 1.00 14.03  ? 43  VAL A C   1 
ATOM   353  O  O   . VAL A 1 43  ? 129.065 107.811 113.012 1.00 14.03  ? 43  VAL A O   1 
ATOM   354  C  CB  . VAL A 1 43  ? 131.311 106.042 114.802 1.00 14.03  ? 43  VAL A CB  1 
ATOM   355  C  CG1 . VAL A 1 43  ? 130.097 106.313 115.662 1.00 14.03  ? 43  VAL A CG1 1 
ATOM   356  C  CG2 . VAL A 1 43  ? 131.664 104.570 114.838 1.00 14.03  ? 43  VAL A CG2 1 
ATOM   357  N  N   . VAL A 1 44  ? 130.946 108.918 113.565 1.00 15.98  ? 44  VAL A N   1 
ATOM   358  C  CA  . VAL A 1 44  ? 130.265 110.209 113.553 1.00 15.98  ? 44  VAL A CA  1 
ATOM   359  C  C   . VAL A 1 44  ? 129.740 110.528 112.158 1.00 15.98  ? 44  VAL A C   1 
ATOM   360  O  O   . VAL A 1 44  ? 128.607 110.995 112.001 1.00 15.98  ? 44  VAL A O   1 
ATOM   361  C  CB  . VAL A 1 44  ? 131.199 111.314 114.078 1.00 15.98  ? 44  VAL A CB  1 
ATOM   362  C  CG1 . VAL A 1 44  ? 130.549 112.668 113.925 1.00 15.98  ? 44  VAL A CG1 1 
ATOM   363  C  CG2 . VAL A 1 44  ? 131.538 111.063 115.534 1.00 15.98  ? 44  VAL A CG2 1 
ATOM   364  N  N   . ALA A 1 45  ? 130.545 110.273 111.123 1.00 30.81  ? 45  ALA A N   1 
ATOM   365  C  CA  . ALA A 1 45  ? 130.103 110.553 109.761 1.00 30.81  ? 45  ALA A CA  1 
ATOM   366  C  C   . ALA A 1 45  ? 128.923 109.675 109.364 1.00 30.81  ? 45  ALA A C   1 
ATOM   367  O  O   . ALA A 1 45  ? 127.984 110.146 108.711 1.00 30.81  ? 45  ALA A O   1 
ATOM   368  C  CB  . ALA A 1 45  ? 131.262 110.365 108.784 1.00 30.81  ? 45  ALA A CB  1 
ATOM   369  N  N   . THR A 1 46  ? 128.956 108.393 109.733 1.00 14.49  ? 46  THR A N   1 
ATOM   370  C  CA  . THR A 1 46  ? 127.845 107.508 109.409 1.00 14.49  ? 46  THR A CA  1 
ATOM   371  C  C   . THR A 1 46  ? 126.566 107.965 110.093 1.00 14.49  ? 46  THR A C   1 
ATOM   372  O  O   . THR A 1 46  ? 125.496 107.993 109.472 1.00 14.49  ? 46  THR A O   1 
ATOM   373  C  CB  . THR A 1 46  ? 128.180 106.072 109.808 1.00 14.49  ? 46  THR A CB  1 
ATOM   374  O  OG1 . THR A 1 46  ? 129.502 105.750 109.362 1.00 14.49  ? 46  THR A OG1 1 
ATOM   375  C  CG2 . THR A 1 46  ? 127.197 105.106 109.180 1.00 14.49  ? 46  THR A CG2 1 
ATOM   376  N  N   . PHE A 1 47  ? 126.657 108.347 111.369 1.00 14.78  ? 47  PHE A N   1 
ATOM   377  C  CA  . PHE A 1 47  ? 125.464 108.815 112.066 1.00 14.78  ? 47  PHE A CA  1 
ATOM   378  C  C   . PHE A 1 47  ? 124.990 110.161 111.531 1.00 14.78  ? 47  PHE A C   1 
ATOM   379  O  O   . PHE A 1 47  ? 123.800 110.475 111.623 1.00 14.78  ? 47  PHE A O   1 
ATOM   380  C  CB  . PHE A 1 47  ? 125.727 108.904 113.567 1.00 14.78  ? 47  PHE A CB  1 
ATOM   381  C  CG  . PHE A 1 47  ? 125.867 107.570 114.238 1.00 14.78  ? 47  PHE A CG  1 
ATOM   382  C  CD1 . PHE A 1 47  ? 125.440 106.415 113.611 1.00 14.78  ? 47  PHE A CD1 1 
ATOM   383  C  CD2 . PHE A 1 47  ? 126.425 107.473 115.499 1.00 14.78  ? 47  PHE A CD2 1 
ATOM   384  C  CE1 . PHE A 1 47  ? 125.572 105.192 114.226 1.00 14.78  ? 47  PHE A CE1 1 
ATOM   385  C  CE2 . PHE A 1 47  ? 126.556 106.251 116.119 1.00 14.78  ? 47  PHE A CE2 1 
ATOM   386  C  CZ  . PHE A 1 47  ? 126.130 105.110 115.482 1.00 14.78  ? 47  PHE A CZ  1 
ATOM   387  N  N   . TRP A 1 48  ? 125.899 110.972 110.987 1.00 15.82  ? 48  TRP A N   1 
ATOM   388  C  CA  . TRP A 1 48  ? 125.499 112.260 110.433 1.00 15.82  ? 48  TRP A CA  1 
ATOM   389  C  C   . TRP A 1 48  ? 124.806 112.113 109.083 1.00 15.82  ? 48  TRP A C   1 
ATOM   390  O  O   . TRP A 1 48  ? 123.794 112.776 108.834 1.00 15.82  ? 48  TRP A O   1 
ATOM   391  C  CB  . TRP A 1 48  ? 126.713 113.181 110.321 1.00 15.82  ? 48  TRP A CB  1 
ATOM   392  C  CG  . TRP A 1 48  ? 126.974 113.952 111.576 1.00 15.82  ? 48  TRP A CG  1 
ATOM   393  C  CD1 . TRP A 1 48  ? 126.113 114.132 112.618 1.00 15.82  ? 48  TRP A CD1 1 
ATOM   394  C  CD2 . TRP A 1 48  ? 128.174 114.652 111.924 1.00 15.82  ? 48  TRP A CD2 1 
ATOM   395  N  NE1 . TRP A 1 48  ? 126.701 114.897 113.592 1.00 15.82  ? 48  TRP A NE1 1 
ATOM   396  C  CE2 . TRP A 1 48  ? 127.968 115.230 113.190 1.00 15.82  ? 48  TRP A CE2 1 
ATOM   397  C  CE3 . TRP A 1 48  ? 129.402 114.844 111.287 1.00 15.82  ? 48  TRP A CE3 1 
ATOM   398  C  CZ2 . TRP A 1 48  ? 128.942 115.985 113.831 1.00 15.82  ? 48  TRP A CZ2 1 
ATOM   399  C  CZ3 . TRP A 1 48  ? 130.367 115.595 111.925 1.00 15.82  ? 48  TRP A CZ3 1 
ATOM   400  C  CH2 . TRP A 1 48  ? 130.132 116.156 113.184 1.00 15.82  ? 48  TRP A CH2 1 
ATOM   401  N  N   . LEU A 1 49  ? 125.332 111.266 108.193 1.00 18.57  ? 49  LEU A N   1 
ATOM   402  C  CA  . LEU A 1 49  ? 124.634 111.018 106.932 1.00 18.57  ? 49  LEU A CA  1 
ATOM   403  C  C   . LEU A 1 49  ? 123.314 110.294 107.157 1.00 18.57  ? 49  LEU A C   1 
ATOM   404  O  O   . LEU A 1 49  ? 122.267 110.727 106.664 1.00 18.57  ? 49  LEU A O   1 
ATOM   405  C  CB  . LEU A 1 49  ? 125.506 110.223 105.958 1.00 18.57  ? 49  LEU A CB  1 
ATOM   406  C  CG  . LEU A 1 49  ? 126.574 110.924 105.117 1.00 18.57  ? 49  LEU A CG  1 
ATOM   407  C  CD1 . LEU A 1 49  ? 127.751 111.376 105.931 1.00 18.57  ? 49  LEU A CD1 1 
ATOM   408  C  CD2 . LEU A 1 49  ? 127.025 110.003 103.995 1.00 18.57  ? 49  LEU A CD2 1 
ATOM   409  N  N   . THR A 1 50  ? 123.338 109.188 107.903 1.00 16.60  ? 50  THR A N   1 
ATOM   410  C  CA  . THR A 1 50  ? 122.128 108.395 108.062 1.00 16.60  ? 50  THR A CA  1 
ATOM   411  C  C   . THR A 1 50  ? 121.116 109.055 108.987 1.00 16.60  ? 50  THR A C   1 
ATOM   412  O  O   . THR A 1 50  ? 119.929 108.721 108.919 1.00 16.60  ? 50  THR A O   1 
ATOM   413  C  CB  . THR A 1 50  ? 122.479 107.003 108.582 1.00 16.60  ? 50  THR A CB  1 
ATOM   414  O  OG1 . THR A 1 50  ? 123.145 107.120 109.844 1.00 16.60  ? 50  THR A OG1 1 
ATOM   415  C  CG2 . THR A 1 50  ? 123.390 106.292 107.602 1.00 16.60  ? 50  THR A CG2 1 
ATOM   416  N  N   . GLU A 1 51  ? 121.558 109.982 109.837 1.00 18.59  ? 51  GLU A N   1 
ATOM   417  C  CA  . GLU A 1 51  ? 120.694 110.636 110.822 1.00 18.59  ? 51  GLU A CA  1 
ATOM   418  C  C   . GLU A 1 51  ? 119.990 109.611 111.707 1.00 18.59  ? 51  GLU A C   1 
ATOM   419  O  O   . GLU A 1 51  ? 118.835 109.788 112.097 1.00 18.59  ? 51  GLU A O   1 
ATOM   420  C  CB  . GLU A 1 51  ? 119.683 111.567 110.149 1.00 18.59  ? 51  GLU A CB  1 
ATOM   421  C  CG  . GLU A 1 51  ? 120.314 112.776 109.482 1.00 18.59  ? 51  GLU A CG  1 
ATOM   422  C  CD  . GLU A 1 51  ? 119.296 113.675 108.806 1.00 18.59  ? 51  GLU A CD  1 
ATOM   423  O  OE1 . GLU A 1 51  ? 118.108 113.295 108.747 1.00 18.59  ? 51  GLU A OE1 1 
ATOM   424  O  OE2 . GLU A 1 51  ? 119.688 114.763 108.333 1.00 18.59  ? 51  GLU A OE2 1 
ATOM   425  N  N   . ALA A 1 52  ? 120.696 108.521 112.019 1.00 15.64  ? 52  ALA A N   1 
ATOM   426  C  CA  . ALA A 1 52  ? 120.159 107.535 112.950 1.00 15.64  ? 52  ALA A CA  1 
ATOM   427  C  C   . ALA A 1 52  ? 119.998 108.133 114.339 1.00 15.64  ? 52  ALA A C   1 
ATOM   428  O  O   . ALA A 1 52  ? 119.004 107.873 115.027 1.00 15.64  ? 52  ALA A O   1 
ATOM   429  C  CB  . ALA A 1 52  ? 121.062 106.304 112.992 1.00 15.64  ? 52  ALA A CB  1 
ATOM   430  N  N   . LEU A 1 53  ? 120.963 108.931 114.767 1.00 11.61  ? 53  LEU A N   1 
ATOM   431  C  CA  . LEU A 1 53  ? 120.915 109.667 116.016 1.00 11.61  ? 53  LEU A CA  1 
ATOM   432  C  C   . LEU A 1 53  ? 120.740 111.152 115.735 1.00 11.61  ? 53  LEU A C   1 
ATOM   433  O  O   . LEU A 1 53  ? 121.092 111.632 114.653 1.00 11.61  ? 53  LEU A O   1 
ATOM   434  C  CB  . LEU A 1 53  ? 122.200 109.443 116.825 1.00 11.61  ? 53  LEU A CB  1 
ATOM   435  C  CG  . LEU A 1 53  ? 122.306 108.149 117.631 1.00 11.61  ? 53  LEU A CG  1 
ATOM   436  C  CD1 . LEU A 1 53  ? 123.608 108.119 118.402 1.00 11.61  ? 53  LEU A CD1 1 
ATOM   437  C  CD2 . LEU A 1 53  ? 121.128 108.002 118.571 1.00 11.61  ? 53  LEU A CD2 1 
ATOM   438  N  N   . PRO A 1 54  ? 120.183 111.910 116.678 1.00 10.38  ? 54  PRO A N   1 
ATOM   439  C  CA  . PRO A 1 54  ? 120.082 113.361 116.481 1.00 10.38  ? 54  PRO A CA  1 
ATOM   440  C  C   . PRO A 1 54  ? 121.459 113.974 116.280 1.00 10.38  ? 54  PRO A C   1 
ATOM   441  O  O   . PRO A 1 54  ? 122.452 113.514 116.846 1.00 10.38  ? 54  PRO A O   1 
ATOM   442  C  CB  . PRO A 1 54  ? 119.426 113.850 117.776 1.00 10.38  ? 54  PRO A CB  1 
ATOM   443  C  CG  . PRO A 1 54  ? 118.682 112.669 118.285 1.00 10.38  ? 54  PRO A CG  1 
ATOM   444  C  CD  . PRO A 1 54  ? 119.502 111.472 117.907 1.00 10.38  ? 54  PRO A CD  1 
ATOM   445  N  N   . LEU A 1 55  ? 121.511 115.020 115.450 1.00 11.51  ? 55  LEU A N   1 
ATOM   446  C  CA  . LEU A 1 55  ? 122.796 115.578 115.043 1.00 11.51  ? 55  LEU A CA  1 
ATOM   447  C  C   . LEU A 1 55  ? 123.609 116.059 116.235 1.00 11.51  ? 55  LEU A C   1 
ATOM   448  O  O   . LEU A 1 55  ? 124.831 115.876 116.265 1.00 11.51  ? 55  LEU A O   1 
ATOM   449  C  CB  . LEU A 1 55  ? 122.583 116.716 114.047 1.00 11.51  ? 55  LEU A CB  1 
ATOM   450  C  CG  . LEU A 1 55  ? 121.775 116.362 112.798 1.00 11.51  ? 55  LEU A CG  1 
ATOM   451  C  CD1 . LEU A 1 55  ? 121.730 117.536 111.838 1.00 11.51  ? 55  LEU A CD1 1 
ATOM   452  C  CD2 . LEU A 1 55  ? 122.352 115.135 112.120 1.00 11.51  ? 55  LEU A CD2 1 
ATOM   453  N  N   . SER A 1 56  ? 122.962 116.668 117.224 1.00 10.34  ? 56  SER A N   1 
ATOM   454  C  CA  . SER A 1 56  ? 123.660 117.077 118.435 1.00 10.34  ? 56  SER A CA  1 
ATOM   455  C  C   . SER A 1 56  ? 124.065 115.895 119.304 1.00 10.34  ? 56  SER A C   1 
ATOM   456  O  O   . SER A 1 56  ? 125.135 115.926 119.926 1.00 10.34  ? 56  SER A O   1 
ATOM   457  C  CB  . SER A 1 56  ? 122.784 118.037 119.237 1.00 10.34  ? 56  SER A CB  1 
ATOM   458  O  OG  . SER A 1 56  ? 122.438 119.164 118.455 1.00 10.34  ? 56  SER A OG  1 
ATOM   459  N  N   . VAL A 1 57  ? 123.240 114.847 119.352 1.00 10.21  ? 57  VAL A N   1 
ATOM   460  C  CA  . VAL A 1 57  ? 123.617 113.639 120.077 1.00 10.21  ? 57  VAL A CA  1 
ATOM   461  C  C   . VAL A 1 57  ? 124.859 113.014 119.455 1.00 10.21  ? 57  VAL A C   1 
ATOM   462  O  O   . VAL A 1 57  ? 125.771 112.576 120.164 1.00 10.21  ? 57  VAL A O   1 
ATOM   463  C  CB  . VAL A 1 57  ? 122.439 112.651 120.112 1.00 10.21  ? 57  VAL A CB  1 
ATOM   464  C  CG1 . VAL A 1 57  ? 122.872 111.325 120.707 1.00 10.21  ? 57  VAL A CG1 1 
ATOM   465  C  CG2 . VAL A 1 57  ? 121.287 113.240 120.898 1.00 10.21  ? 57  VAL A CG2 1 
ATOM   466  N  N   . THR A 1 58  ? 124.914 112.962 118.122 1.00 10.06  ? 58  THR A N   1 
ATOM   467  C  CA  . THR A 1 58  ? 126.124 112.499 117.453 1.00 10.06  ? 58  THR A CA  1 
ATOM   468  C  C   . THR A 1 58  ? 127.298 113.433 117.710 1.00 10.06  ? 58  THR A C   1 
ATOM   469  O  O   . THR A 1 58  ? 128.431 112.972 117.880 1.00 10.06  ? 58  THR A O   1 
ATOM   470  C  CB  . THR A 1 58  ? 125.881 112.367 115.951 1.00 10.06  ? 58  THR A CB  1 
ATOM   471  O  OG1 . THR A 1 58  ? 124.702 111.587 115.723 1.00 10.06  ? 58  THR A OG1 1 
ATOM   472  C  CG2 . THR A 1 58  ? 127.064 111.697 115.284 1.00 10.06  ? 58  THR A CG2 1 
ATOM   473  N  N   . ALA A 1 59  ? 127.052 114.744 117.735 1.00 9.74   ? 59  ALA A N   1 
ATOM   474  C  CA  . ALA A 1 59  ? 128.119 115.698 118.004 1.00 9.74   ? 59  ALA A CA  1 
ATOM   475  C  C   . ALA A 1 59  ? 128.701 115.535 119.400 1.00 9.74   ? 59  ALA A C   1 
ATOM   476  O  O   . ALA A 1 59  ? 129.873 115.860 119.612 1.00 9.74   ? 59  ALA A O   1 
ATOM   477  C  CB  . ALA A 1 59  ? 127.606 117.124 117.822 1.00 9.74   ? 59  ALA A CB  1 
ATOM   478  N  N   . LEU A 1 60  ? 127.911 115.054 120.351 1.00 10.00  ? 60  LEU A N   1 
ATOM   479  C  CA  . LEU A 1 60  ? 128.410 114.796 121.696 1.00 10.00  ? 60  LEU A CA  1 
ATOM   480  C  C   . LEU A 1 60  ? 129.170 113.479 121.810 1.00 10.00  ? 60  LEU A C   1 
ATOM   481  O  O   . LEU A 1 60  ? 129.730 113.199 122.873 1.00 10.00  ? 60  LEU A O   1 
ATOM   482  C  CB  . LEU A 1 60  ? 127.260 114.810 122.705 1.00 10.00  ? 60  LEU A CB  1 
ATOM   483  C  CG  . LEU A 1 60  ? 126.624 116.170 122.984 1.00 10.00  ? 60  LEU A CG  1 
ATOM   484  C  CD1 . LEU A 1 60  ? 125.166 116.009 123.378 1.00 10.00  ? 60  LEU A CD1 1 
ATOM   485  C  CD2 . LEU A 1 60  ? 127.398 116.907 124.060 1.00 10.00  ? 60  LEU A CD2 1 
ATOM   486  N  N   . LEU A 1 61  ? 129.205 112.669 120.755 1.00 11.22  ? 61  LEU A N   1 
ATOM   487  C  CA  . LEU A 1 61  ? 129.900 111.385 120.794 1.00 11.22  ? 61  LEU A CA  1 
ATOM   488  C  C   . LEU A 1 61  ? 131.419 111.529 120.875 1.00 11.22  ? 61  LEU A C   1 
ATOM   489  O  O   . LEU A 1 61  ? 132.065 110.683 121.505 1.00 11.22  ? 61  LEU A O   1 
ATOM   490  C  CB  . LEU A 1 61  ? 129.528 110.523 119.585 1.00 11.22  ? 61  LEU A CB  1 
ATOM   491  C  CG  . LEU A 1 61  ? 128.156 109.849 119.598 1.00 11.22  ? 61  LEU A CG  1 
ATOM   492  C  CD1 . LEU A 1 61  ? 128.006 108.933 118.398 1.00 11.22  ? 61  LEU A CD1 1 
ATOM   493  C  CD2 . LEU A 1 61  ? 127.956 109.077 120.886 1.00 11.22  ? 61  LEU A CD2 1 
ATOM   494  N  N   . PRO A 1 62  ? 132.041 112.528 120.230 1.00 11.04  ? 62  PRO A N   1 
ATOM   495  C  CA  . PRO A 1 62  ? 133.485 112.719 120.455 1.00 11.04  ? 62  PRO A CA  1 
ATOM   496  C  C   . PRO A 1 62  ? 133.856 112.884 121.917 1.00 11.04  ? 62  PRO A C   1 
ATOM   497  O  O   . PRO A 1 62  ? 134.856 112.308 122.360 1.00 11.04  ? 62  PRO A O   1 
ATOM   498  C  CB  . PRO A 1 62  ? 133.808 113.984 119.650 1.00 11.04  ? 62  PRO A CB  1 
ATOM   499  C  CG  . PRO A 1 62  ? 132.687 114.177 118.705 1.00 11.04  ? 62  PRO A CG  1 
ATOM   500  C  CD  . PRO A 1 62  ? 131.597 113.199 118.995 1.00 11.04  ? 62  PRO A CD  1 
ATOM   501  N  N   . SER A 1 63  ? 133.062 113.630 122.689 1.00 12.88  ? 63  SER A N   1 
ATOM   502  C  CA  . SER A 1 63  ? 133.374 113.847 124.098 1.00 12.88  ? 63  SER A CA  1 
ATOM   503  C  C   . SER A 1 63  ? 133.257 112.573 124.921 1.00 12.88  ? 63  SER A C   1 
ATOM   504  O  O   . SER A 1 63  ? 133.749 112.533 126.053 1.00 12.88  ? 63  SER A O   1 
ATOM   505  C  CB  . SER A 1 63  ? 132.463 114.928 124.676 1.00 12.88  ? 63  SER A CB  1 
ATOM   506  O  OG  . SER A 1 63  ? 131.131 114.756 124.231 1.00 12.88  ? 63  SER A OG  1 
ATOM   507  N  N   . LEU A 1 64  ? 132.609 111.543 124.386 1.00 12.20  ? 64  LEU A N   1 
ATOM   508  C  CA  . LEU A 1 64  ? 132.522 110.240 125.029 1.00 12.20  ? 64  LEU A CA  1 
ATOM   509  C  C   . LEU A 1 64  ? 133.566 109.263 124.510 1.00 12.20  ? 64  LEU A C   1 
ATOM   510  O  O   . LEU A 1 64  ? 134.012 108.389 125.258 1.00 12.20  ? 64  LEU A O   1 
ATOM   511  C  CB  . LEU A 1 64  ? 131.118 109.659 124.819 1.00 12.20  ? 64  LEU A CB  1 
ATOM   512  C  CG  . LEU A 1 64  ? 130.803 108.174 125.013 1.00 12.20  ? 64  LEU A CG  1 
ATOM   513  C  CD1 . LEU A 1 64  ? 131.219 107.680 126.389 1.00 12.20  ? 64  LEU A CD1 1 
ATOM   514  C  CD2 . LEU A 1 64  ? 129.327 107.917 124.770 1.00 12.20  ? 64  LEU A CD2 1 
ATOM   515  N  N   . MET A 1 65  ? 133.986 109.413 123.256 1.00 13.33  ? 65  MET A N   1 
ATOM   516  C  CA  . MET A 1 65  ? 134.855 108.444 122.602 1.00 13.33  ? 65  MET A CA  1 
ATOM   517  C  C   . MET A 1 65  ? 136.332 108.806 122.731 1.00 13.33  ? 65  MET A C   1 
ATOM   518  O  O   . MET A 1 65  ? 137.151 107.948 123.073 1.00 13.33  ? 65  MET A O   1 
ATOM   519  C  CB  . MET A 1 65  ? 134.467 108.322 121.126 1.00 13.33  ? 65  MET A CB  1 
ATOM   520  C  CG  . MET A 1 65  ? 133.467 107.220 120.838 1.00 13.33  ? 65  MET A CG  1 
ATOM   521  S  SD  . MET A 1 65  ? 132.962 107.187 119.111 1.00 13.33  ? 65  MET A SD  1 
ATOM   522  C  CE  . MET A 1 65  ? 132.122 105.611 119.038 1.00 13.33  ? 65  MET A CE  1 
ATOM   523  N  N   . LEU A 1 66  ? 136.690 110.059 122.449 1.00 13.91  ? 66  LEU A N   1 
ATOM   524  C  CA  . LEU A 1 66  ? 138.093 110.463 122.527 1.00 13.91  ? 66  LEU A CA  1 
ATOM   525  C  C   . LEU A 1 66  ? 138.686 110.297 123.921 1.00 13.91  ? 66  LEU A C   1 
ATOM   526  O  O   . LEU A 1 66  ? 139.801 109.758 124.027 1.00 13.91  ? 66  LEU A O   1 
ATOM   527  C  CB  . LEU A 1 66  ? 138.243 111.902 122.020 1.00 13.91  ? 66  LEU A CB  1 
ATOM   528  C  CG  . LEU A 1 66  ? 137.729 112.197 120.610 1.00 13.91  ? 66  LEU A CG  1 
ATOM   529  C  CD1 . LEU A 1 66  ? 137.902 113.662 120.273 1.00 13.91  ? 66  LEU A CD1 1 
ATOM   530  C  CD2 . LEU A 1 66  ? 138.434 111.334 119.584 1.00 13.91  ? 66  LEU A CD2 1 
ATOM   531  N  N   . PRO A 1 67  ? 138.043 110.739 125.011 1.00 14.86  ? 67  PRO A N   1 
ATOM   532  C  CA  . PRO A 1 67  ? 138.635 110.483 126.337 1.00 14.86  ? 67  PRO A CA  1 
ATOM   533  C  C   . PRO A 1 67  ? 138.787 109.008 126.661 1.00 14.86  ? 67  PRO A C   1 
ATOM   534  O  O   . PRO A 1 67  ? 139.780 108.615 127.285 1.00 14.86  ? 67  PRO A O   1 
ATOM   535  C  CB  . PRO A 1 67  ? 137.662 111.174 127.302 1.00 14.86  ? 67  PRO A CB  1 
ATOM   536  C  CG  . PRO A 1 67  ? 136.866 112.095 126.481 1.00 14.86  ? 67  PRO A CG  1 
ATOM   537  C  CD  . PRO A 1 67  ? 136.803 111.530 125.113 1.00 14.86  ? 67  PRO A CD  1 
ATOM   538  N  N   . MET A 1 68  ? 137.826 108.175 126.255 1.00 15.99  ? 68  MET A N   1 
ATOM   539  C  CA  . MET A 1 68  ? 137.912 106.749 126.555 1.00 15.99  ? 68  MET A CA  1 
ATOM   540  C  C   . MET A 1 68  ? 139.014 106.078 125.747 1.00 15.99  ? 68  MET A C   1 
ATOM   541  O  O   . MET A 1 68  ? 139.719 105.201 126.258 1.00 15.99  ? 68  MET A O   1 
ATOM   542  C  CB  . MET A 1 68  ? 136.565 106.077 126.296 1.00 15.99  ? 68  MET A CB  1 
ATOM   543  C  CG  . MET A 1 68  ? 135.538 106.332 127.382 1.00 15.99  ? 68  MET A CG  1 
ATOM   544  S  SD  . MET A 1 68  ? 134.122 105.226 127.283 1.00 15.99  ? 68  MET A SD  1 
ATOM   545  C  CE  . MET A 1 68  ? 134.773 103.774 128.100 1.00 15.99  ? 68  MET A CE  1 
ATOM   546  N  N   . PHE A 1 69  ? 139.177 106.474 124.484 1.00 16.48  ? 69  PHE A N   1 
ATOM   547  C  CA  . PHE A 1 69  ? 140.258 105.935 123.670 1.00 16.48  ? 69  PHE A CA  1 
ATOM   548  C  C   . PHE A 1 69  ? 141.625 106.408 124.141 1.00 16.48  ? 69  PHE A C   1 
ATOM   549  O  O   . PHE A 1 69  ? 142.639 105.831 123.737 1.00 16.48  ? 69  PHE A O   1 
ATOM   550  C  CB  . PHE A 1 69  ? 140.057 106.322 122.206 1.00 16.48  ? 69  PHE A CB  1 
ATOM   551  C  CG  . PHE A 1 69  ? 139.139 105.404 121.457 1.00 16.48  ? 69  PHE A CG  1 
ATOM   552  C  CD1 . PHE A 1 69  ? 139.393 104.046 121.399 1.00 16.48  ? 69  PHE A CD1 1 
ATOM   553  C  CD2 . PHE A 1 69  ? 138.024 105.898 120.807 1.00 16.48  ? 69  PHE A CD2 1 
ATOM   554  C  CE1 . PHE A 1 69  ? 138.551 103.201 120.709 1.00 16.48  ? 69  PHE A CE1 1 
ATOM   555  C  CE2 . PHE A 1 69  ? 137.179 105.057 120.116 1.00 16.48  ? 69  PHE A CE2 1 
ATOM   556  C  CZ  . PHE A 1 69  ? 137.443 103.708 120.068 1.00 16.48  ? 69  PHE A CZ  1 
ATOM   557  N  N   . GLY A 1 70  ? 141.676 107.438 124.980 1.00 19.74  ? 70  GLY A N   1 
ATOM   558  C  CA  . GLY A 1 70  ? 142.932 107.988 125.438 1.00 19.74  ? 70  GLY A CA  1 
ATOM   559  C  C   . GLY A 1 70  ? 143.570 108.992 124.508 1.00 19.74  ? 70  GLY A C   1 
ATOM   560  O  O   . GLY A 1 70  ? 144.754 109.305 124.682 1.00 19.74  ? 70  GLY A O   1 
ATOM   561  N  N   . ILE A 1 71  ? 142.834 109.498 123.519 1.00 17.64  ? 71  ILE A N   1 
ATOM   562  C  CA  . ILE A 1 71  ? 143.415 110.437 122.564 1.00 17.64  ? 71  ILE A CA  1 
ATOM   563  C  C   . ILE A 1 71  ? 143.713 111.772 123.236 1.00 17.64  ? 71  ILE A C   1 
ATOM   564  O  O   . ILE A 1 71  ? 144.805 112.330 123.082 1.00 17.64  ? 71  ILE A O   1 
ATOM   565  C  CB  . ILE A 1 71  ? 142.491 110.598 121.346 1.00 17.64  ? 71  ILE A CB  1 
ATOM   566  C  CG1 . ILE A 1 71  ? 142.413 109.276 120.582 1.00 17.64  ? 71  ILE A CG1 1 
ATOM   567  C  CG2 . ILE A 1 71  ? 142.988 111.707 120.443 1.00 17.64  ? 71  ILE A CG2 1 
ATOM   568  C  CD1 . ILE A 1 71  ? 141.352 109.240 119.525 1.00 17.64  ? 71  ILE A CD1 1 
ATOM   569  N  N   . MET A 1 72  ? 142.756 112.302 123.996 1.00 20.15  ? 72  MET A N   1 
ATOM   570  C  CA  . MET A 1 72  ? 142.989 113.520 124.760 1.00 20.15  ? 72  MET A CA  1 
ATOM   571  C  C   . MET A 1 72  ? 142.011 113.562 125.922 1.00 20.15  ? 72  MET A C   1 
ATOM   572  O  O   . MET A 1 72  ? 140.940 112.952 125.844 1.00 20.15  ? 72  MET A O   1 
ATOM   573  C  CB  . MET A 1 72  ? 142.845 114.772 123.880 1.00 20.15  ? 72  MET A CB  1 
ATOM   574  C  CG  . MET A 1 72  ? 141.546 114.901 123.113 1.00 20.15  ? 72  MET A CG  1 
ATOM   575  S  SD  . MET A 1 72  ? 141.514 116.490 122.260 1.00 20.15  ? 72  MET A SD  1 
ATOM   576  C  CE  . MET A 1 72  ? 139.941 116.417 121.418 1.00 20.15  ? 72  MET A CE  1 
ATOM   577  N  N   . PRO A 1 73  ? 142.344 114.265 127.006 1.00 18.30  ? 73  PRO A N   1 
ATOM   578  C  CA  . PRO A 1 73  ? 141.477 114.256 128.188 1.00 18.30  ? 73  PRO A CA  1 
ATOM   579  C  C   . PRO A 1 73  ? 140.127 114.896 127.909 1.00 18.30  ? 73  PRO A C   1 
ATOM   580  O  O   . PRO A 1 73  ? 139.966 115.701 126.991 1.00 18.30  ? 73  PRO A O   1 
ATOM   581  C  CB  . PRO A 1 73  ? 142.271 115.068 129.218 1.00 18.30  ? 73  PRO A CB  1 
ATOM   582  C  CG  . PRO A 1 73  ? 143.679 115.003 128.748 1.00 18.30  ? 73  PRO A CG  1 
ATOM   583  C  CD  . PRO A 1 73  ? 143.595 114.996 127.257 1.00 18.30  ? 73  PRO A CD  1 
ATOM   584  N  N   . SER A 1 74  ? 139.143 114.516 128.728 1.00 15.91  ? 74  SER A N   1 
ATOM   585  C  CA  . SER A 1 74  ? 137.788 115.027 128.552 1.00 15.91  ? 74  SER A CA  1 
ATOM   586  C  C   . SER A 1 74  ? 137.725 116.539 128.708 1.00 15.91  ? 74  SER A C   1 
ATOM   587  O  O   . SER A 1 74  ? 136.855 117.186 128.116 1.00 15.91  ? 74  SER A O   1 
ATOM   588  C  CB  . SER A 1 74  ? 136.844 114.356 129.547 1.00 15.91  ? 74  SER A CB  1 
ATOM   589  O  OG  . SER A 1 74  ? 135.625 115.069 129.645 1.00 15.91  ? 74  SER A OG  1 
ATOM   590  N  N   . LYS A 1 75  ? 138.626 117.118 129.504 1.00 16.55  ? 75  LYS A N   1 
ATOM   591  C  CA  . LYS A 1 75  ? 138.627 118.565 129.691 1.00 16.55  ? 75  LYS A CA  1 
ATOM   592  C  C   . LYS A 1 75  ? 138.944 119.295 128.391 1.00 16.55  ? 75  LYS A C   1 
ATOM   593  O  O   . LYS A 1 75  ? 138.300 120.297 128.063 1.00 16.55  ? 75  LYS A O   1 
ATOM   594  C  CB  . LYS A 1 75  ? 139.618 118.946 130.788 1.00 16.55  ? 75  LYS A CB  1 
ATOM   595  C  CG  . LYS A 1 75  ? 139.440 118.143 132.064 1.00 16.55  ? 75  LYS A CG  1 
ATOM   596  C  CD  . LYS A 1 75  ? 140.055 118.845 133.260 1.00 16.55  ? 75  LYS A CD  1 
ATOM   597  C  CE  . LYS A 1 75  ? 139.421 118.371 134.557 1.00 16.55  ? 75  LYS A CE  1 
ATOM   598  N  NZ  . LYS A 1 75  ? 139.894 117.018 134.950 1.00 16.55  ? 75  LYS A NZ  1 
ATOM   599  N  N   . LYS A 1 76  ? 139.926 118.804 127.632 1.00 16.80  ? 76  LYS A N   1 
ATOM   600  C  CA  . LYS A 1 76  ? 140.245 119.421 126.347 1.00 16.80  ? 76  LYS A CA  1 
ATOM   601  C  C   . LYS A 1 76  ? 139.093 119.276 125.359 1.00 16.80  ? 76  LYS A C   1 
ATOM   602  O  O   . LYS A 1 76  ? 138.768 120.219 124.623 1.00 16.80  ? 76  LYS A O   1 
ATOM   603  C  CB  . LYS A 1 76  ? 141.519 118.803 125.774 1.00 16.80  ? 76  LYS A CB  1 
ATOM   604  C  CG  . LYS A 1 76  ? 142.780 119.163 126.536 1.00 16.80  ? 76  LYS A CG  1 
ATOM   605  C  CD  . LYS A 1 76  ? 144.016 118.973 125.674 1.00 16.80  ? 76  LYS A CD  1 
ATOM   606  C  CE  . LYS A 1 76  ? 143.862 119.666 124.331 1.00 16.80  ? 76  LYS A CE  1 
ATOM   607  N  NZ  . LYS A 1 76  ? 143.666 121.133 124.482 1.00 16.80  ? 76  LYS A NZ  1 
ATOM   608  N  N   . VAL A 1 77  ? 138.462 118.102 125.327 1.00 13.65  ? 77  VAL A N   1 
ATOM   609  C  CA  . VAL A 1 77  ? 137.342 117.896 124.417 1.00 13.65  ? 77  VAL A CA  1 
ATOM   610  C  C   . VAL A 1 77  ? 136.205 118.847 124.758 1.00 13.65  ? 77  VAL A C   1 
ATOM   611  O  O   . VAL A 1 77  ? 135.597 119.452 123.870 1.00 13.65  ? 77  VAL A O   1 
ATOM   612  C  CB  . VAL A 1 77  ? 136.882 116.429 124.448 1.00 13.65  ? 77  VAL A CB  1 
ATOM   613  C  CG1 . VAL A 1 77  ? 135.952 116.159 123.289 1.00 13.65  ? 77  VAL A CG1 1 
ATOM   614  C  CG2 . VAL A 1 77  ? 138.074 115.499 124.404 1.00 13.65  ? 77  VAL A CG2 1 
ATOM   615  N  N   . ALA A 1 78  ? 135.908 119.002 126.050 1.00 12.09  ? 78  ALA A N   1 
ATOM   616  C  CA  . ALA A 1 78  ? 134.890 119.961 126.462 1.00 12.09  ? 78  ALA A CA  1 
ATOM   617  C  C   . ALA A 1 78  ? 135.280 121.383 126.089 1.00 12.09  ? 78  ALA A C   1 
ATOM   618  O  O   . ALA A 1 78  ? 134.431 122.162 125.643 1.00 12.09  ? 78  ALA A O   1 
ATOM   619  C  CB  . ALA A 1 78  ? 134.650 119.857 127.966 1.00 12.09  ? 78  ALA A CB  1 
ATOM   620  N  N   . SER A 1 79  ? 136.554 121.737 126.263 1.00 13.45  ? 79  SER A N   1 
ATOM   621  C  CA  . SER A 1 79  ? 137.029 123.063 125.888 1.00 13.45  ? 79  SER A CA  1 
ATOM   622  C  C   . SER A 1 79  ? 136.891 123.327 124.398 1.00 13.45  ? 79  SER A C   1 
ATOM   623  O  O   . SER A 1 79  ? 136.770 124.488 123.993 1.00 13.45  ? 79  SER A O   1 
ATOM   624  C  CB  . SER A 1 79  ? 138.488 123.229 126.309 1.00 13.45  ? 79  SER A CB  1 
ATOM   625  O  OG  . SER A 1 79  ? 139.118 124.254 125.564 1.00 13.45  ? 79  SER A OG  1 
ATOM   626  N  N   . ALA A 1 80  ? 136.912 122.283 123.576 1.00 12.51  ? 80  ALA A N   1 
ATOM   627  C  CA  . ALA A 1 80  ? 136.821 122.450 122.130 1.00 12.51  ? 80  ALA A CA  1 
ATOM   628  C  C   . ALA A 1 80  ? 135.401 122.697 121.625 1.00 12.51  ? 80  ALA A C   1 
ATOM   629  O  O   . ALA A 1 80  ? 135.228 122.940 120.428 1.00 12.51  ? 80  ALA A O   1 
ATOM   630  C  CB  . ALA A 1 80  ? 137.403 121.223 121.423 1.00 12.51  ? 80  ALA A CB  1 
ATOM   631  N  N   . TYR A 1 81  ? 134.386 122.647 122.488 1.00 12.12  ? 81  TYR A N   1 
ATOM   632  C  CA  . TYR A 1 81  ? 133.002 122.775 122.040 1.00 12.12  ? 81  TYR A CA  1 
ATOM   633  C  C   . TYR A 1 81  ? 132.500 124.209 121.944 1.00 12.12  ? 81  TYR A C   1 
ATOM   634  O  O   . TYR A 1 81  ? 131.378 124.412 121.470 1.00 12.12  ? 81  TYR A O   1 
ATOM   635  C  CB  . TYR A 1 81  ? 132.053 122.001 122.961 1.00 12.12  ? 81  TYR A CB  1 
ATOM   636  C  CG  . TYR A 1 81  ? 131.866 120.545 122.610 1.00 12.12  ? 81  TYR A CG  1 
ATOM   637  C  CD1 . TYR A 1 81  ? 132.931 119.666 122.601 1.00 12.12  ? 81  TYR A CD1 1 
ATOM   638  C  CD2 . TYR A 1 81  ? 130.611 120.055 122.279 1.00 12.12  ? 81  TYR A CD2 1 
ATOM   639  C  CE1 . TYR A 1 81  ? 132.755 118.338 122.284 1.00 12.12  ? 81  TYR A CE1 1 
ATOM   640  C  CE2 . TYR A 1 81  ? 130.428 118.730 121.956 1.00 12.12  ? 81  TYR A CE2 1 
ATOM   641  C  CZ  . TYR A 1 81  ? 131.504 117.877 121.959 1.00 12.12  ? 81  TYR A CZ  1 
ATOM   642  O  OH  . TYR A 1 81  ? 131.329 116.554 121.637 1.00 12.12  ? 81  TYR A OH  1 
ATOM   643  N  N   . PHE A 1 82  ? 133.268 125.205 122.372 1.00 12.54  ? 82  PHE A N   1 
ATOM   644  C  CA  . PHE A 1 82  ? 132.768 126.572 122.377 1.00 12.54  ? 82  PHE A CA  1 
ATOM   645  C  C   . PHE A 1 82  ? 133.849 127.475 121.807 1.00 12.54  ? 82  PHE A C   1 
ATOM   646  O  O   . PHE A 1 82  ? 134.997 127.425 122.256 1.00 12.54  ? 82  PHE A O   1 
ATOM   647  C  CB  . PHE A 1 82  ? 132.392 127.014 123.796 1.00 12.54  ? 82  PHE A CB  1 
ATOM   648  C  CG  . PHE A 1 82  ? 131.307 128.051 123.851 1.00 12.54  ? 82  PHE A CG  1 
ATOM   649  C  CD1 . PHE A 1 82  ? 129.978 127.669 123.867 1.00 12.54  ? 82  PHE A CD1 1 
ATOM   650  C  CD2 . PHE A 1 82  ? 131.607 129.400 123.881 1.00 12.54  ? 82  PHE A CD2 1 
ATOM   651  C  CE1 . PHE A 1 82  ? 128.972 128.612 123.923 1.00 12.54  ? 82  PHE A CE1 1 
ATOM   652  C  CE2 . PHE A 1 82  ? 130.606 130.349 123.935 1.00 12.54  ? 82  PHE A CE2 1 
ATOM   653  C  CZ  . PHE A 1 82  ? 129.287 129.953 123.956 1.00 12.54  ? 82  PHE A CZ  1 
ATOM   654  N  N   . LYS A 1 83  ? 133.490 128.290 120.818 1.00 13.68  ? 83  LYS A N   1 
ATOM   655  C  CA  . LYS A 1 83  ? 134.458 129.130 120.129 1.00 13.68  ? 83  LYS A CA  1 
ATOM   656  C  C   . LYS A 1 83  ? 133.835 130.502 119.896 1.00 13.68  ? 83  LYS A C   1 
ATOM   657  O  O   . LYS A 1 83  ? 132.727 130.792 120.356 1.00 13.68  ? 83  LYS A O   1 
ATOM   658  C  CB  . LYS A 1 83  ? 134.914 128.468 118.822 1.00 13.68  ? 83  LYS A CB  1 
ATOM   659  C  CG  . LYS A 1 83  ? 135.773 127.232 119.025 1.00 13.68  ? 83  LYS A CG  1 
ATOM   660  C  CD  . LYS A 1 83  ? 136.920 127.178 118.036 1.00 13.68  ? 83  LYS A CD  1 
ATOM   661  C  CE  . LYS A 1 83  ? 137.721 125.897 118.199 1.00 13.68  ? 83  LYS A CE  1 
ATOM   662  N  NZ  . LYS A 1 83  ? 137.916 125.551 119.631 1.00 13.68  ? 83  LYS A NZ  1 
ATOM   663  N  N   . ASP A 1 84  ? 134.567 131.356 119.176 1.00 18.74  ? 84  ASP A N   1 
ATOM   664  C  CA  . ASP A 1 84  ? 134.090 132.705 118.888 1.00 18.74  ? 84  ASP A CA  1 
ATOM   665  C  C   . ASP A 1 84  ? 132.819 132.686 118.048 1.00 18.74  ? 84  ASP A C   1 
ATOM   666  O  O   . ASP A 1 84  ? 132.003 133.616 118.125 1.00 18.74  ? 84  ASP A O   1 
ATOM   667  C  CB  . ASP A 1 84  ? 135.191 133.491 118.178 1.00 18.74  ? 84  ASP A CB  1 
ATOM   668  C  CG  . ASP A 1 84  ? 134.949 134.980 118.195 1.00 18.74  ? 84  ASP A CG  1 
ATOM   669  O  OD1 . ASP A 1 84  ? 135.107 135.595 119.269 1.00 18.74  ? 84  ASP A OD1 1 
ATOM   670  O  OD2 . ASP A 1 84  ? 134.613 135.541 117.131 1.00 18.74  ? 84  ASP A OD2 1 
ATOM   671  N  N   . PHE A 1 85  ? 132.636 131.636 117.244 1.00 15.27  ? 85  PHE A N   1 
ATOM   672  C  CA  . PHE A 1 85  ? 131.431 131.516 116.433 1.00 15.27  ? 85  PHE A CA  1 
ATOM   673  C  C   . PHE A 1 85  ? 130.185 131.487 117.307 1.00 15.27  ? 85  PHE A C   1 
ATOM   674  O  O   . PHE A 1 85  ? 129.155 132.065 116.948 1.00 15.27  ? 85  PHE A O   1 
ATOM   675  C  CB  . PHE A 1 85  ? 131.516 130.261 115.563 1.00 15.27  ? 85  PHE A CB  1 
ATOM   676  C  CG  . PHE A 1 85  ? 130.180 129.690 115.180 1.00 15.27  ? 85  PHE A CG  1 
ATOM   677  C  CD1 . PHE A 1 85  ? 129.438 130.254 114.159 1.00 15.27  ? 85  PHE A CD1 1 
ATOM   678  C  CD2 . PHE A 1 85  ? 129.673 128.583 115.835 1.00 15.27  ? 85  PHE A CD2 1 
ATOM   679  C  CE1 . PHE A 1 85  ? 128.212 129.728 113.805 1.00 15.27  ? 85  PHE A CE1 1 
ATOM   680  C  CE2 . PHE A 1 85  ? 128.447 128.055 115.485 1.00 15.27  ? 85  PHE A CE2 1 
ATOM   681  C  CZ  . PHE A 1 85  ? 127.717 128.627 114.469 1.00 15.27  ? 85  PHE A CZ  1 
ATOM   682  N  N   . HIS A 1 86  ? 130.261 130.829 118.464 1.00 12.92  ? 86  HIS A N   1 
ATOM   683  C  CA  . HIS A 1 86  ? 129.104 130.759 119.350 1.00 12.92  ? 86  HIS A CA  1 
ATOM   684  C  C   . HIS A 1 86  ? 128.789 132.116 119.967 1.00 12.92  ? 86  HIS A C   1 
ATOM   685  O  O   . HIS A 1 86  ? 127.616 132.472 120.127 1.00 12.92  ? 86  HIS A O   1 
ATOM   686  C  CB  . HIS A 1 86  ? 129.340 129.709 120.431 1.00 12.92  ? 86  HIS A CB  1 
ATOM   687  C  CG  . HIS A 1 86  ? 129.583 128.336 119.889 1.00 12.92  ? 86  HIS A CG  1 
ATOM   688  N  ND1 . HIS A 1 86  ? 130.807 127.936 119.399 1.00 12.92  ? 86  HIS A ND1 1 
ATOM   689  C  CD2 . HIS A 1 86  ? 128.757 127.274 119.749 1.00 12.92  ? 86  HIS A CD2 1 
ATOM   690  C  CE1 . HIS A 1 86  ? 130.726 126.684 118.986 1.00 12.92  ? 86  HIS A CE1 1 
ATOM   691  N  NE2 . HIS A 1 86  ? 129.492 126.259 119.187 1.00 12.92  ? 86  HIS A NE2 1 
ATOM   692  N  N   . LEU A 1 87  ? 129.818 132.887 120.328 1.00 14.33  ? 87  LEU A N   1 
ATOM   693  C  CA  . LEU A 1 87  ? 129.579 134.235 120.834 1.00 14.33  ? 87  LEU A CA  1 
ATOM   694  C  C   . LEU A 1 87  ? 128.931 135.110 119.769 1.00 14.33  ? 87  LEU A C   1 
ATOM   695  O  O   . LEU A 1 87  ? 127.988 135.860 120.056 1.00 14.33  ? 87  LEU A O   1 
ATOM   696  C  CB  . LEU A 1 87  ? 130.888 134.856 121.319 1.00 14.33  ? 87  LEU A CB  1 
ATOM   697  C  CG  . LEU A 1 87  ? 131.551 134.200 122.530 1.00 14.33  ? 87  LEU A CG  1 
ATOM   698  C  CD1 . LEU A 1 87  ? 132.776 134.986 122.955 1.00 14.33  ? 87  LEU A CD1 1 
ATOM   699  C  CD2 . LEU A 1 87  ? 130.569 134.076 123.680 1.00 14.33  ? 87  LEU A CD2 1 
ATOM   700  N  N   . LEU A 1 88  ? 129.417 135.015 118.529 1.00 17.12  ? 88  LEU A N   1 
ATOM   701  C  CA  . LEU A 1 88  ? 128.783 135.742 117.433 1.00 17.12  ? 88  LEU A CA  1 
ATOM   702  C  C   . LEU A 1 88  ? 127.333 135.312 117.255 1.00 17.12  ? 88  LEU A C   1 
ATOM   703  O  O   . LEU A 1 88  ? 126.445 136.149 117.048 1.00 17.12  ? 88  LEU A O   1 
ATOM   704  C  CB  . LEU A 1 88  ? 129.563 135.515 116.140 1.00 17.12  ? 88  LEU A CB  1 
ATOM   705  C  CG  . LEU A 1 88  ? 129.271 136.473 114.991 1.00 17.12  ? 88  LEU A CG  1 
ATOM   706  C  CD1 . LEU A 1 88  ? 129.862 137.825 115.298 1.00 17.12  ? 88  LEU A CD1 1 
ATOM   707  C  CD2 . LEU A 1 88  ? 129.825 135.928 113.691 1.00 17.12  ? 88  LEU A CD2 1 
ATOM   708  N  N   . LEU A 1 89  ? 127.079 134.005 117.332 1.00 13.65  ? 89  LEU A N   1 
ATOM   709  C  CA  . LEU A 1 89  ? 125.727 133.494 117.162 1.00 13.65  ? 89  LEU A CA  1 
ATOM   710  C  C   . LEU A 1 89  ? 124.799 134.024 118.244 1.00 13.65  ? 89  LEU A C   1 
ATOM   711  O  O   . LEU A 1 89  ? 123.666 134.410 117.956 1.00 13.65  ? 89  LEU A O   1 
ATOM   712  C  CB  . LEU A 1 89  ? 125.745 131.967 117.166 1.00 13.65  ? 89  LEU A CB  1 
ATOM   713  C  CG  . LEU A 1 89  ? 124.415 131.262 116.914 1.00 13.65  ? 89  LEU A CG  1 
ATOM   714  C  CD1 . LEU A 1 89  ? 123.851 131.669 115.566 1.00 13.65  ? 89  LEU A CD1 1 
ATOM   715  C  CD2 . LEU A 1 89  ? 124.598 129.758 116.986 1.00 13.65  ? 89  LEU A CD2 1 
ATOM   716  N  N   . ILE A 1 90  ? 125.264 134.057 119.493 1.00 13.28  ? 90  ILE A N   1 
ATOM   717  C  CA  . ILE A 1 90  ? 124.446 134.599 120.578 1.00 13.28  ? 90  ILE A CA  1 
ATOM   718  C  C   . ILE A 1 90  ? 124.158 136.076 120.337 1.00 13.28  ? 90  ILE A C   1 
ATOM   719  O  O   . ILE A 1 90  ? 123.014 136.542 120.467 1.00 13.28  ? 90  ILE A O   1 
ATOM   720  C  CB  . ILE A 1 90  ? 125.143 134.375 121.932 1.00 13.28  ? 90  ILE A CB  1 
ATOM   721  C  CG1 . ILE A 1 90  ? 125.133 132.892 122.299 1.00 13.28  ? 90  ILE A CG1 1 
ATOM   722  C  CG2 . ILE A 1 90  ? 124.483 135.203 123.018 1.00 13.28  ? 90  ILE A CG2 1 
ATOM   723  C  CD1 . ILE A 1 90  ? 125.974 132.562 123.504 1.00 13.28  ? 90  ILE A CD1 1 
ATOM   724  N  N   . GLY A 1 91  ? 125.194 136.832 119.966 1.00 14.09  ? 91  GLY A N   1 
ATOM   725  C  CA  . GLY A 1 91  ? 125.016 138.257 119.751 1.00 14.09  ? 91  GLY A CA  1 
ATOM   726  C  C   . GLY A 1 91  ? 124.030 138.568 118.643 1.00 14.09  ? 91  GLY A C   1 
ATOM   727  O  O   . GLY A 1 91  ? 123.272 139.537 118.729 1.00 14.09  ? 91  GLY A O   1 
ATOM   728  N  N   . VAL A 1 92  ? 124.025 137.756 117.586 1.00 14.33  ? 92  VAL A N   1 
ATOM   729  C  CA  . VAL A 1 92  ? 123.104 138.029 116.485 1.00 14.33  ? 92  VAL A CA  1 
ATOM   730  C  C   . VAL A 1 92  ? 121.720 137.437 116.751 1.00 14.33  ? 92  VAL A C   1 
ATOM   731  O  O   . VAL A 1 92  ? 120.715 137.968 116.266 1.00 14.33  ? 92  VAL A O   1 
ATOM   732  C  CB  . VAL A 1 92  ? 123.687 137.526 115.155 1.00 14.33  ? 92  VAL A CB  1 
ATOM   733  C  CG1 . VAL A 1 92  ? 122.811 137.967 114.000 1.00 14.33  ? 92  VAL A CG1 1 
ATOM   734  C  CG2 . VAL A 1 92  ? 125.089 138.061 114.965 1.00 14.33  ? 92  VAL A CG2 1 
ATOM   735  N  N   . ILE A 1 93  ? 121.631 136.347 117.516 1.00 12.87  ? 93  ILE A N   1 
ATOM   736  C  CA  . ILE A 1 93  ? 120.327 135.799 117.869 1.00 12.87  ? 93  ILE A CA  1 
ATOM   737  C  C   . ILE A 1 93  ? 119.572 136.750 118.783 1.00 12.87  ? 93  ILE A C   1 
ATOM   738  O  O   . ILE A 1 93  ? 118.340 136.817 118.730 1.00 12.87  ? 93  ILE A O   1 
ATOM   739  C  CB  . ILE A 1 93  ? 120.478 134.397 118.490 1.00 12.87  ? 93  ILE A CB  1 
ATOM   740  C  CG1 . ILE A 1 93  ? 120.859 133.381 117.414 1.00 12.87  ? 93  ILE A CG1 1 
ATOM   741  C  CG2 . ILE A 1 93  ? 119.203 133.958 119.183 1.00 12.87  ? 93  ILE A CG2 1 
ATOM   742  C  CD1 . ILE A 1 93  ? 119.828 133.246 116.319 1.00 12.87  ? 93  ILE A CD1 1 
ATOM   743  N  N   . CYS A 1 94  ? 120.278 137.510 119.622 1.00 16.23  ? 94  CYS A N   1 
ATOM   744  C  CA  . CYS A 1 94  ? 119.594 138.554 120.384 1.00 16.23  ? 94  CYS A CA  1 
ATOM   745  C  C   . CYS A 1 94  ? 118.885 139.534 119.451 1.00 16.23  ? 94  CYS A C   1 
ATOM   746  O  O   . CYS A 1 94  ? 117.700 139.847 119.634 1.00 16.23  ? 94  CYS A O   1 
ATOM   747  C  CB  . CYS A 1 94  ? 120.586 139.286 121.286 1.00 16.23  ? 94  CYS A CB  1 
ATOM   748  S  SG  . CYS A 1 94  ? 121.339 138.255 122.560 1.00 16.23  ? 94  CYS A SG  1 
ATOM   749  N  N   . LEU A 1 95  ? 119.591 140.002 118.419 1.00 15.77  ? 95  LEU A N   1 
ATOM   750  C  CA  . LEU A 1 95  ? 118.997 140.935 117.466 1.00 15.77  ? 95  LEU A CA  1 
ATOM   751  C  C   . LEU A 1 95  ? 117.855 140.291 116.689 1.00 15.77  ? 95  LEU A C   1 
ATOM   752  O  O   . LEU A 1 95  ? 116.833 140.934 116.428 1.00 15.77  ? 95  LEU A O   1 
ATOM   753  C  CB  . LEU A 1 95  ? 120.072 141.450 116.511 1.00 15.77  ? 95  LEU A CB  1 
ATOM   754  C  CG  . LEU A 1 95  ? 119.620 142.249 115.291 1.00 15.77  ? 95  LEU A CG  1 
ATOM   755  C  CD1 . LEU A 1 95  ? 118.837 143.480 115.702 1.00 15.77  ? 95  LEU A CD1 1 
ATOM   756  C  CD2 . LEU A 1 95  ? 120.823 142.633 114.456 1.00 15.77  ? 95  LEU A CD2 1 
ATOM   757  N  N   . ALA A 1 96  ? 118.018 139.026 116.295 1.00 14.55  ? 96  ALA A N   1 
ATOM   758  C  CA  . ALA A 1 96  ? 116.964 138.340 115.553 1.00 14.55  ? 96  ALA A CA  1 
ATOM   759  C  C   . ALA A 1 96  ? 115.708 138.175 116.401 1.00 14.55  ? 96  ALA A C   1 
ATOM   760  O  O   . ALA A 1 96  ? 114.586 138.334 115.903 1.00 14.55  ? 96  ALA A O   1 
ATOM   761  C  CB  . ALA A 1 96  ? 117.465 136.983 115.063 1.00 14.55  ? 96  ALA A CB  1 
ATOM   762  N  N   . THR A 1 97  ? 115.878 137.847 117.684 1.00 13.39  ? 97  THR A N   1 
ATOM   763  C  CA  . THR A 1 97  ? 114.739 137.762 118.589 1.00 13.39  ? 97  THR A CA  1 
ATOM   764  C  C   . THR A 1 97  ? 114.054 139.111 118.733 1.00 13.39  ? 97  THR A C   1 
ATOM   765  O  O   . THR A 1 97  ? 112.820 139.194 118.728 1.00 13.39  ? 97  THR A O   1 
ATOM   766  C  CB  . THR A 1 97  ? 115.192 137.254 119.956 1.00 13.39  ? 97  THR A CB  1 
ATOM   767  O  OG1 . THR A 1 97  ? 115.911 136.026 119.797 1.00 13.39  ? 97  THR A OG1 1 
ATOM   768  C  CG2 . THR A 1 97  ? 113.996 137.026 120.861 1.00 13.39  ? 97  THR A CG2 1 
ATOM   769  N  N   . SER A 1 98  ? 114.841 140.182 118.860 1.00 15.34  ? 98  SER A N   1 
ATOM   770  C  CA  . SER A 1 98  ? 114.248 141.512 118.958 1.00 15.34  ? 98  SER A CA  1 
ATOM   771  C  C   . SER A 1 98  ? 113.474 141.865 117.695 1.00 15.34  ? 98  SER A C   1 
ATOM   772  O  O   . SER A 1 98  ? 112.417 142.502 117.764 1.00 15.34  ? 98  SER A O   1 
ATOM   773  C  CB  . SER A 1 98  ? 115.332 142.551 119.230 1.00 15.34  ? 98  SER A CB  1 
ATOM   774  O  OG  . SER A 1 98  ? 114.759 143.776 119.649 1.00 15.34  ? 98  SER A OG  1 
ATOM   775  N  N   . ILE A 1 99  ? 113.991 141.472 116.531 1.00 16.96  ? 99  ILE A N   1 
ATOM   776  C  CA  . ILE A 1 99  ? 113.305 141.761 115.273 1.00 16.96  ? 99  ILE A CA  1 
ATOM   777  C  C   . ILE A 1 99  ? 111.990 140.997 115.192 1.00 16.96  ? 99  ILE A C   1 
ATOM   778  O  O   . ILE A 1 99  ? 110.942 141.564 114.863 1.00 16.96  ? 99  ILE A O   1 
ATOM   779  C  CB  . ILE A 1 99  ? 114.215 141.438 114.075 1.00 16.96  ? 99  ILE A CB  1 
ATOM   780  C  CG1 . ILE A 1 99  ? 115.318 142.487 113.945 1.00 16.96  ? 99  ILE A CG1 1 
ATOM   781  C  CG2 . ILE A 1 99  ? 113.408 141.352 112.795 1.00 16.96  ? 99  ILE A CG2 1 
ATOM   782  C  CD1 . ILE A 1 99  ? 116.347 142.154 112.906 1.00 16.96  ? 99  ILE A CD1 1 
ATOM   783  N  N   . GLU A 1 100 ? 112.024 139.697 115.492 1.00 20.77  ? 100 GLU A N   1 
ATOM   784  C  CA  . GLU A 1 100 ? 110.822 138.883 115.336 1.00 20.77  ? 100 GLU A CA  1 
ATOM   785  C  C   . GLU A 1 100 ? 109.755 139.255 116.358 1.00 20.77  ? 100 GLU A C   1 
ATOM   786  O  O   . GLU A 1 100 ? 108.562 139.276 116.034 1.00 20.77  ? 100 GLU A O   1 
ATOM   787  C  CB  . GLU A 1 100 ? 111.162 137.399 115.451 1.00 20.77  ? 100 GLU A CB  1 
ATOM   788  C  CG  . GLU A 1 100 ? 109.952 136.496 115.284 1.00 20.77  ? 100 GLU A CG  1 
ATOM   789  C  CD  . GLU A 1 100 ? 110.256 135.043 115.570 1.00 20.77  ? 100 GLU A CD  1 
ATOM   790  O  OE1 . GLU A 1 100 ? 110.592 134.725 116.730 1.00 20.77  ? 100 GLU A OE1 1 
ATOM   791  O  OE2 . GLU A 1 100 ? 110.161 134.219 114.638 1.00 20.77  ? 100 GLU A OE2 1 
ATOM   792  N  N   . LYS A 1 101 ? 110.161 139.545 117.596 1.00 16.90  ? 101 LYS A N   1 
ATOM   793  C  CA  . LYS A 1 101 ? 109.188 139.772 118.659 1.00 16.90  ? 101 LYS A CA  1 
ATOM   794  C  C   . LYS A 1 101 ? 108.322 140.994 118.380 1.00 16.90  ? 101 LYS A C   1 
ATOM   795  O  O   . LYS A 1 101 ? 107.108 140.969 118.613 1.00 16.90  ? 101 LYS A O   1 
ATOM   796  C  CB  . LYS A 1 101 ? 109.906 139.921 119.999 1.00 16.90  ? 101 LYS A CB  1 
ATOM   797  C  CG  . LYS A 1 101 ? 108.980 140.171 121.172 1.00 16.90  ? 101 LYS A CG  1 
ATOM   798  C  CD  . LYS A 1 101 ? 109.757 140.619 122.394 1.00 16.90  ? 101 LYS A CD  1 
ATOM   799  C  CE  . LYS A 1 101 ? 108.836 140.836 123.580 1.00 16.90  ? 101 LYS A CE  1 
ATOM   800  N  NZ  . LYS A 1 101 ? 109.595 141.143 124.823 1.00 16.90  ? 101 LYS A NZ  1 
ATOM   801  N  N   . TRP A 1 102 ? 108.922 142.069 117.876 1.00 23.05  ? 102 TRP A N   1 
ATOM   802  C  CA  . TRP A 1 102 ? 108.219 143.329 117.684 1.00 23.05  ? 102 TRP A CA  1 
ATOM   803  C  C   . TRP A 1 102 ? 107.663 143.488 116.276 1.00 23.05  ? 102 TRP A C   1 
ATOM   804  O  O   . TRP A 1 102 ? 107.464 144.622 115.825 1.00 23.05  ? 102 TRP A O   1 
ATOM   805  C  CB  . TRP A 1 102 ? 109.141 144.497 118.031 1.00 23.05  ? 102 TRP A CB  1 
ATOM   806  C  CG  . TRP A 1 102 ? 109.632 144.417 119.432 1.00 23.05  ? 102 TRP A CG  1 
ATOM   807  C  CD1 . TRP A 1 102 ? 110.906 144.172 119.840 1.00 23.05  ? 102 TRP A CD1 1 
ATOM   808  C  CD2 . TRP A 1 102 ? 108.847 144.555 120.621 1.00 23.05  ? 102 TRP A CD2 1 
ATOM   809  N  NE1 . TRP A 1 102 ? 110.968 144.159 121.211 1.00 23.05  ? 102 TRP A NE1 1 
ATOM   810  C  CE2 . TRP A 1 102 ? 109.715 144.393 121.714 1.00 23.05  ? 102 TRP A CE2 1 
ATOM   811  C  CE3 . TRP A 1 102 ? 107.495 144.808 120.866 1.00 23.05  ? 102 TRP A CE3 1 
ATOM   812  C  CZ2 . TRP A 1 102 ? 109.277 144.475 123.032 1.00 23.05  ? 102 TRP A CZ2 1 
ATOM   813  C  CZ3 . TRP A 1 102 ? 107.063 144.888 122.174 1.00 23.05  ? 102 TRP A CZ3 1 
ATOM   814  C  CH2 . TRP A 1 102 ? 107.950 144.723 123.239 1.00 23.05  ? 102 TRP A CH2 1 
ATOM   815  N  N   . ASN A 1 103 ? 107.419 142.380 115.575 1.00 28.35  ? 103 ASN A N   1 
ATOM   816  C  CA  . ASN A 1 103 ? 106.695 142.379 114.305 1.00 28.35  ? 103 ASN A CA  1 
ATOM   817  C  C   . ASN A 1 103 ? 107.392 143.223 113.241 1.00 28.35  ? 103 ASN A C   1 
ATOM   818  O  O   . ASN A 1 103 ? 106.750 143.743 112.326 1.00 28.35  ? 103 ASN A O   1 
ATOM   819  C  CB  . ASN A 1 103 ? 105.252 142.850 114.500 1.00 28.35  ? 103 ASN A CB  1 
ATOM   820  C  CG  . ASN A 1 103 ? 104.319 142.309 113.446 1.00 28.35  ? 103 ASN A CG  1 
ATOM   821  O  OD1 . ASN A 1 103 ? 104.627 141.323 112.780 1.00 28.35  ? 103 ASN A OD1 1 
ATOM   822  N  ND2 . ASN A 1 103 ? 103.166 142.947 113.290 1.00 28.35  ? 103 ASN A ND2 1 
ATOM   823  N  N   . LEU A 1 104 ? 108.712 143.371 113.352 1.00 26.20  ? 104 LEU A N   1 
ATOM   824  C  CA  . LEU A 1 104 ? 109.470 144.080 112.328 1.00 26.20  ? 104 LEU A CA  1 
ATOM   825  C  C   . LEU A 1 104 ? 109.630 143.247 111.064 1.00 26.20  ? 104 LEU A C   1 
ATOM   826  O  O   . LEU A 1 104 ? 109.701 143.803 109.959 1.00 26.20  ? 104 LEU A O   1 
ATOM   827  C  CB  . LEU A 1 104 ? 110.843 144.472 112.873 1.00 26.20  ? 104 LEU A CB  1 
ATOM   828  C  CG  . LEU A 1 104 ? 111.757 145.301 111.973 1.00 26.20  ? 104 LEU A CG  1 
ATOM   829  C  CD1 . LEU A 1 104 ? 111.007 146.467 111.358 1.00 26.20  ? 104 LEU A CD1 1 
ATOM   830  C  CD2 . LEU A 1 104 ? 112.954 145.785 112.765 1.00 26.20  ? 104 LEU A CD2 1 
ATOM   831  N  N   . HIS A 1 105 ? 109.686 141.921 111.210 1.00 33.42  ? 105 HIS A N   1 
ATOM   832  C  CA  . HIS A 1 105 ? 109.862 141.059 110.049 1.00 33.42  ? 105 HIS A CA  1 
ATOM   833  C  C   . HIS A 1 105 ? 108.697 141.197 109.081 1.00 33.42  ? 105 HIS A C   1 
ATOM   834  O  O   . HIS A 1 105 ? 108.901 141.263 107.866 1.00 33.42  ? 105 HIS A O   1 
ATOM   835  C  CB  . HIS A 1 105 ? 110.036 139.605 110.490 1.00 33.42  ? 105 HIS A CB  1 
ATOM   836  C  CG  . HIS A 1 105 ? 108.867 139.052 111.242 1.00 33.42  ? 105 HIS A CG  1 
ATOM   837  N  ND1 . HIS A 1 105 ? 108.549 139.448 112.523 1.00 33.42  ? 105 HIS A ND1 1 
ATOM   838  C  CD2 . HIS A 1 105 ? 107.942 138.126 110.895 1.00 33.42  ? 105 HIS A CD2 1 
ATOM   839  C  CE1 . HIS A 1 105 ? 107.477 138.793 112.931 1.00 33.42  ? 105 HIS A CE1 1 
ATOM   840  N  NE2 . HIS A 1 105 ? 107.089 137.985 111.962 1.00 33.42  ? 105 HIS A NE2 1 
ATOM   841  N  N   . LYS A 1 106 ? 107.468 141.264 109.599 1.00 34.64  ? 106 LYS A N   1 
ATOM   842  C  CA  . LYS A 1 106 ? 106.314 141.434 108.721 1.00 34.64  ? 106 LYS A CA  1 
ATOM   843  C  C   . LYS A 1 106 ? 106.334 142.790 108.029 1.00 34.64  ? 106 LYS A C   1 
ATOM   844  O  O   . LYS A 1 106 ? 105.958 142.895 106.858 1.00 34.64  ? 106 LYS A O   1 
ATOM   845  C  CB  . LYS A 1 106 ? 105.014 141.251 109.502 1.00 34.64  ? 106 LYS A CB  1 
ATOM   846  C  CG  . LYS A 1 106 ? 104.718 139.810 109.876 1.00 34.64  ? 106 LYS A CG  1 
ATOM   847  C  CD  . LYS A 1 106 ? 103.304 139.656 110.412 1.00 34.64  ? 106 LYS A CD  1 
ATOM   848  C  CE  . LYS A 1 106 ? 103.058 138.244 110.917 1.00 34.64  ? 106 LYS A CE  1 
ATOM   849  N  NZ  . LYS A 1 106 ? 103.253 137.227 109.848 1.00 34.64  ? 106 LYS A NZ  1 
ATOM   850  N  N   . ARG A 1 107 ? 106.760 143.841 108.733 1.00 35.20  ? 107 ARG A N   1 
ATOM   851  C  CA  . ARG A 1 107 ? 106.832 145.161 108.111 1.00 35.20  ? 107 ARG A CA  1 
ATOM   852  C  C   . ARG A 1 107 ? 107.833 145.173 106.963 1.00 35.20  ? 107 ARG A C   1 
ATOM   853  O  O   . ARG A 1 107 ? 107.529 145.649 105.860 1.00 35.20  ? 107 ARG A O   1 
ATOM   854  C  CB  . ARG A 1 107 ? 107.197 146.216 109.154 1.00 35.20  ? 107 ARG A CB  1 
ATOM   855  C  CG  . ARG A 1 107 ? 107.679 147.526 108.556 1.00 35.20  ? 107 ARG A CG  1 
ATOM   856  C  CD  . ARG A 1 107 ? 107.638 148.653 109.573 1.00 35.20  ? 107 ARG A CD  1 
ATOM   857  N  NE  . ARG A 1 107 ? 106.281 149.135 109.797 1.00 35.20  ? 107 ARG A NE  1 
ATOM   858  C  CZ  . ARG A 1 107 ? 105.559 148.863 110.874 1.00 35.20  ? 107 ARG A CZ  1 
ATOM   859  N  NH1 . ARG A 1 107 ? 106.038 148.119 111.857 1.00 35.20  ? 107 ARG A NH1 1 
ATOM   860  N  NH2 . ARG A 1 107 ? 104.325 149.348 110.967 1.00 35.20  ? 107 ARG A NH2 1 
ATOM   861  N  N   . ILE A 1 108 ? 109.035 144.641 107.201 1.00 34.26  ? 108 ILE A N   1 
ATOM   862  C  CA  . ILE A 1 108 ? 110.036 144.581 106.138 1.00 34.26  ? 108 ILE A CA  1 
ATOM   863  C  C   . ILE A 1 108 ? 109.545 143.701 104.996 1.00 34.26  ? 108 ILE A C   1 
ATOM   864  O  O   . ILE A 1 108 ? 109.741 144.020 103.817 1.00 34.26  ? 108 ILE A O   1 
ATOM   865  C  CB  . ILE A 1 108 ? 111.385 144.088 106.694 1.00 34.26  ? 108 ILE A CB  1 
ATOM   866  C  CG1 . ILE A 1 108 ? 111.940 145.082 107.712 1.00 34.26  ? 108 ILE A CG1 1 
ATOM   867  C  CG2 . ILE A 1 108 ? 112.384 143.885 105.572 1.00 34.26  ? 108 ILE A CG2 1 
ATOM   868  C  CD1 . ILE A 1 108 ? 113.251 144.650 108.326 1.00 34.26  ? 108 ILE A CD1 1 
ATOM   869  N  N   . ALA A 1 109 ? 108.893 142.585 105.327 1.00 39.50  ? 109 ALA A N   1 
ATOM   870  C  CA  . ALA A 1 109 ? 108.387 141.674 104.309 1.00 39.50  ? 109 ALA A CA  1 
ATOM   871  C  C   . ALA A 1 109 ? 107.365 142.358 103.414 1.00 39.50  ? 109 ALA A C   1 
ATOM   872  O  O   . ALA A 1 109 ? 107.427 142.252 102.185 1.00 39.50  ? 109 ALA A O   1 
ATOM   873  C  CB  . ALA A 1 109 ? 107.775 140.449 104.985 1.00 39.50  ? 109 ALA A CB  1 
ATOM   874  N  N   . LEU A 1 110 ? 106.413 143.069 104.017 1.00 41.43  ? 110 LEU A N   1 
ATOM   875  C  CA  . LEU A 1 110 ? 105.376 143.727 103.233 1.00 41.43  ? 110 LEU A CA  1 
ATOM   876  C  C   . LEU A 1 110 ? 105.948 144.873 102.411 1.00 41.43  ? 110 LEU A C   1 
ATOM   877  O  O   . LEU A 1 110 ? 105.528 145.090 101.269 1.00 41.43  ? 110 LEU A O   1 
ATOM   878  C  CB  . LEU A 1 110 ? 104.256 144.214 104.149 1.00 41.43  ? 110 LEU A CB  1 
ATOM   879  C  CG  . LEU A 1 110 ? 103.067 143.261 104.280 1.00 41.43  ? 110 LEU A CG  1 
ATOM   880  C  CD1 . LEU A 1 110 ? 103.487 141.952 104.918 1.00 41.43  ? 110 LEU A CD1 1 
ATOM   881  C  CD2 . LEU A 1 110 ? 101.960 143.905 105.087 1.00 41.43  ? 110 LEU A CD2 1 
ATOM   882  N  N   . LYS A 1 111 ? 106.913 145.614 102.964 1.00 43.60  ? 111 LYS A N   1 
ATOM   883  C  CA  . LYS A 1 111 ? 107.550 146.664 102.176 1.00 43.60  ? 111 LYS A CA  1 
ATOM   884  C  C   . LYS A 1 111 ? 108.289 146.082 100.978 1.00 43.60  ? 111 LYS A C   1 
ATOM   885  O  O   . LYS A 1 111 ? 108.216 146.626 99.869  1.00 43.60  ? 111 LYS A O   1 
ATOM   886  C  CB  . LYS A 1 111 ? 108.499 147.482 103.049 1.00 43.60  ? 111 LYS A CB  1 
ATOM   887  C  CG  . LYS A 1 111 ? 109.312 148.505 102.275 1.00 43.60  ? 111 LYS A CG  1 
ATOM   888  C  CD  . LYS A 1 111 ? 108.425 149.564 101.639 1.00 43.60  ? 111 LYS A CD  1 
ATOM   889  C  CE  . LYS A 1 111 ? 107.553 150.254 102.669 1.00 43.60  ? 111 LYS A CE  1 
ATOM   890  N  NZ  . LYS A 1 111 ? 108.366 150.951 103.701 1.00 43.60  ? 111 LYS A NZ  1 
ATOM   891  N  N   . MET A 1 112 ? 109.000 144.969 101.177 1.00 45.79  ? 112 MET A N   1 
ATOM   892  C  CA  . MET A 1 112 ? 109.691 144.326 100.064 1.00 45.79  ? 112 MET A CA  1 
ATOM   893  C  C   . MET A 1 112 ? 108.705 143.830 99.014  1.00 45.79  ? 112 MET A C   1 
ATOM   894  O  O   . MET A 1 112 ? 108.937 143.994 97.811  1.00 45.79  ? 112 MET A O   1 
ATOM   895  C  CB  . MET A 1 112 ? 110.552 143.174 100.578 1.00 45.79  ? 112 MET A CB  1 
ATOM   896  C  CG  . MET A 1 112 ? 111.340 142.457 99.496  1.00 45.79  ? 112 MET A CG  1 
ATOM   897  S  SD  . MET A 1 112 ? 112.197 140.992 100.103 1.00 45.79  ? 112 MET A SD  1 
ATOM   898  C  CE  . MET A 1 112 ? 112.629 141.509 101.761 1.00 45.79  ? 112 MET A CE  1 
ATOM   899  N  N   . VAL A 1 113 ? 107.599 143.223 99.450  1.00 45.38  ? 113 VAL A N   1 
ATOM   900  C  CA  . VAL A 1 113 ? 106.591 142.736 98.511  1.00 45.38  ? 113 VAL A CA  1 
ATOM   901  C  C   . VAL A 1 113 ? 106.006 143.891 97.710  1.00 45.38  ? 113 VAL A C   1 
ATOM   902  O  O   . VAL A 1 113 ? 105.795 143.781 96.496  1.00 45.38  ? 113 VAL A O   1 
ATOM   903  C  CB  . VAL A 1 113 ? 105.497 141.951 99.257  1.00 45.38  ? 113 VAL A CB  1 
ATOM   904  C  CG1 . VAL A 1 113 ? 104.322 141.668 98.337  1.00 45.38  ? 113 VAL A CG1 1 
ATOM   905  C  CG2 . VAL A 1 113 ? 106.060 140.654 99.804  1.00 45.38  ? 113 VAL A CG2 1 
ATOM   906  N  N   . MET A 1 114 ? 105.734 145.015 98.374  1.00 49.67  ? 114 MET A N   1 
ATOM   907  C  CA  . MET A 1 114 ? 105.241 146.191 97.665  1.00 49.67  ? 114 MET A CA  1 
ATOM   908  C  C   . MET A 1 114 ? 106.267 146.701 96.662  1.00 49.67  ? 114 MET A C   1 
ATOM   909  O  O   . MET A 1 114 ? 105.910 147.113 95.552  1.00 49.67  ? 114 MET A O   1 
ATOM   910  C  CB  . MET A 1 114 ? 104.876 147.287 98.666  1.00 49.67  ? 114 MET A CB  1 
ATOM   911  C  CG  . MET A 1 114 ? 103.560 147.056 99.389  1.00 49.67  ? 114 MET A CG  1 
ATOM   912  S  SD  . MET A 1 114 ? 103.100 148.427 100.464 1.00 49.67  ? 114 MET A SD  1 
ATOM   913  C  CE  . MET A 1 114 ? 103.875 149.802 99.619  1.00 49.67  ? 114 MET A CE  1 
ATOM   914  N  N   . MET A 1 115 ? 107.548 146.691 97.038  1.00 54.18  ? 115 MET A N   1 
ATOM   915  C  CA  . MET A 1 115 ? 108.585 147.212 96.152  1.00 54.18  ? 115 MET A CA  1 
ATOM   916  C  C   . MET A 1 115 ? 108.758 146.344 94.910  1.00 54.18  ? 115 MET A C   1 
ATOM   917  O  O   . MET A 1 115 ? 108.753 146.852 93.783  1.00 54.18  ? 115 MET A O   1 
ATOM   918  C  CB  . MET A 1 115 ? 109.909 147.333 96.906  1.00 54.18  ? 115 MET A CB  1 
ATOM   919  C  CG  . MET A 1 115 ? 110.684 148.602 96.591  1.00 54.18  ? 115 MET A CG  1 
ATOM   920  S  SD  . MET A 1 115 ? 109.993 150.070 97.376  1.00 54.18  ? 115 MET A SD  1 
ATOM   921  C  CE  . MET A 1 115 ? 110.833 150.032 98.956  1.00 54.18  ? 115 MET A CE  1 
ATOM   922  N  N   . VAL A 1 116 ? 108.912 145.030 95.088  1.00 54.65  ? 116 VAL A N   1 
ATOM   923  C  CA  . VAL A 1 116 ? 109.291 144.155 93.983  1.00 54.65  ? 116 VAL A CA  1 
ATOM   924  C  C   . VAL A 1 116 ? 108.110 143.349 93.452  1.00 54.65  ? 116 VAL A C   1 
ATOM   925  O  O   . VAL A 1 116 ? 108.313 142.360 92.742  1.00 54.65  ? 116 VAL A O   1 
ATOM   926  C  CB  . VAL A 1 116 ? 110.449 143.222 94.374  1.00 54.65  ? 116 VAL A CB  1 
ATOM   927  C  CG1 . VAL A 1 116 ? 111.690 144.030 94.731  1.00 54.65  ? 116 VAL A CG1 1 
ATOM   928  C  CG2 . VAL A 1 116 ? 110.045 142.289 95.501  1.00 54.65  ? 116 VAL A CG2 1 
ATOM   929  N  N   . GLY A 1 117 ? 106.885 143.744 93.775  1.00 58.90  ? 117 GLY A N   1 
ATOM   930  C  CA  . GLY A 1 117 ? 105.728 143.066 93.225  1.00 58.90  ? 117 GLY A CA  1 
ATOM   931  C  C   . GLY A 1 117 ? 105.501 141.690 93.827  1.00 58.90  ? 117 GLY A C   1 
ATOM   932  O  O   . GLY A 1 117 ? 105.868 141.399 94.970  1.00 58.90  ? 117 GLY A O   1 
ATOM   933  N  N   . VAL A 1 118 ? 104.876 140.827 93.027  1.00 68.87  ? 118 VAL A N   1 
ATOM   934  C  CA  . VAL A 1 118 ? 104.460 139.502 93.468  1.00 68.87  ? 118 VAL A CA  1 
ATOM   935  C  C   . VAL A 1 118 ? 105.076 138.386 92.635  1.00 68.87  ? 118 VAL A C   1 
ATOM   936  O  O   . VAL A 1 118 ? 104.892 137.209 92.965  1.00 68.87  ? 118 VAL A O   1 
ATOM   937  C  CB  . VAL A 1 118 ? 102.921 139.384 93.474  1.00 68.87  ? 118 VAL A CB  1 
ATOM   938  C  CG1 . VAL A 1 118 ? 102.384 139.268 92.052  1.00 68.87  ? 118 VAL A CG1 1 
ATOM   939  C  CG2 . VAL A 1 118 ? 102.445 138.235 94.363  1.00 68.87  ? 118 VAL A CG2 1 
ATOM   940  N  N   . ASN A 1 119 ? 105.810 138.713 91.578  1.00 72.73  ? 119 ASN A N   1 
ATOM   941  C  CA  . ASN A 1 119 ? 106.387 137.686 90.712  1.00 72.73  ? 119 ASN A CA  1 
ATOM   942  C  C   . ASN A 1 119 ? 107.419 136.870 91.481  1.00 72.73  ? 119 ASN A C   1 
ATOM   943  O  O   . ASN A 1 119 ? 108.380 137.445 92.008  1.00 72.73  ? 119 ASN A O   1 
ATOM   944  C  CB  . ASN A 1 119 ? 107.024 138.326 89.484  1.00 72.73  ? 119 ASN A CB  1 
ATOM   945  C  CG  . ASN A 1 119 ? 107.743 137.318 88.613  1.00 72.73  ? 119 ASN A CG  1 
ATOM   946  O  OD1 . ASN A 1 119 ? 107.142 136.362 88.125  1.00 72.73  ? 119 ASN A OD1 1 
ATOM   947  N  ND2 . ASN A 1 119 ? 109.038 137.527 88.413  1.00 72.73  ? 119 ASN A ND2 1 
ATOM   948  N  N   . PRO A 1 120 ? 107.271 135.545 91.564  1.00 66.69  ? 120 PRO A N   1 
ATOM   949  C  CA  . PRO A 1 120 ? 108.158 134.757 92.438  1.00 66.69  ? 120 PRO A CA  1 
ATOM   950  C  C   . PRO A 1 120 ? 109.631 134.853 92.082  1.00 66.69  ? 120 PRO A C   1 
ATOM   951  O  O   . PRO A 1 120 ? 110.475 134.837 92.986  1.00 66.69  ? 120 PRO A O   1 
ATOM   952  C  CB  . PRO A 1 120 ? 107.634 133.324 92.264  1.00 66.69  ? 120 PRO A CB  1 
ATOM   953  C  CG  . PRO A 1 120 ? 106.235 133.483 91.761  1.00 66.69  ? 120 PRO A CG  1 
ATOM   954  C  CD  . PRO A 1 120 ? 106.254 134.709 90.907  1.00 66.69  ? 120 PRO A CD  1 
ATOM   955  N  N   . ALA A 1 121 ? 109.969 134.953 90.796  1.00 66.51  ? 121 ALA A N   1 
ATOM   956  C  CA  . ALA A 1 121 ? 111.375 134.946 90.403  1.00 66.51  ? 121 ALA A CA  1 
ATOM   957  C  C   . ALA A 1 121 ? 112.077 136.237 90.808  1.00 66.51  ? 121 ALA A C   1 
ATOM   958  O  O   . ALA A 1 121 ? 113.224 136.208 91.270  1.00 66.51  ? 121 ALA A O   1 
ATOM   959  C  CB  . ALA A 1 121 ? 111.496 134.711 88.900  1.00 66.51  ? 121 ALA A CB  1 
ATOM   960  N  N   . TRP A 1 122 ? 111.414 137.381 90.634  1.00 70.06  ? 122 TRP A N   1 
ATOM   961  C  CA  . TRP A 1 122 ? 112.002 138.642 91.073  1.00 70.06  ? 122 TRP A CA  1 
ATOM   962  C  C   . TRP A 1 122 ? 112.149 138.681 92.589  1.00 70.06  ? 122 TRP A C   1 
ATOM   963  O  O   . TRP A 1 122 ? 113.146 139.195 93.111  1.00 70.06  ? 122 TRP A O   1 
ATOM   964  C  CB  . TRP A 1 122 ? 111.160 139.813 90.570  1.00 70.06  ? 122 TRP A CB  1 
ATOM   965  C  CG  . TRP A 1 122 ? 111.415 140.133 89.131  1.00 70.06  ? 122 TRP A CG  1 
ATOM   966  C  CD1 . TRP A 1 122 ? 112.235 139.456 88.276  1.00 70.06  ? 122 TRP A CD1 1 
ATOM   967  C  CD2 . TRP A 1 122 ? 110.842 141.205 88.372  1.00 70.06  ? 122 TRP A CD2 1 
ATOM   968  N  NE1 . TRP A 1 122 ? 112.213 140.042 87.035  1.00 70.06  ? 122 TRP A NE1 1 
ATOM   969  C  CE2 . TRP A 1 122 ? 111.365 141.118 87.067  1.00 70.06  ? 122 TRP A CE2 1 
ATOM   970  C  CE3 . TRP A 1 122 ? 109.940 142.230 88.670  1.00 70.06  ? 122 TRP A CE3 1 
ATOM   971  C  CZ2 . TRP A 1 122 ? 111.016 142.016 86.062  1.00 70.06  ? 122 TRP A CZ2 1 
ATOM   972  C  CZ3 . TRP A 1 122 ? 109.594 143.121 87.670  1.00 70.06  ? 122 TRP A CZ3 1 
ATOM   973  C  CH2 . TRP A 1 122 ? 110.131 143.008 86.382  1.00 70.06  ? 122 TRP A CH2 1 
ATOM   974  N  N   . LEU A 1 123 ? 111.166 138.139 93.311  1.00 63.17  ? 123 LEU A N   1 
ATOM   975  C  CA  . LEU A 1 123 ? 111.287 138.033 94.761  1.00 63.17  ? 123 LEU A CA  1 
ATOM   976  C  C   . LEU A 1 123 ? 112.468 137.154 95.150  1.00 63.17  ? 123 LEU A C   1 
ATOM   977  O  O   . LEU A 1 123 ? 113.201 137.470 96.092  1.00 63.17  ? 123 LEU A O   1 
ATOM   978  C  CB  . LEU A 1 123 ? 109.991 137.486 95.358  1.00 63.17  ? 123 LEU A CB  1 
ATOM   979  C  CG  . LEU A 1 123 ? 108.943 138.501 95.819  1.00 63.17  ? 123 LEU A CG  1 
ATOM   980  C  CD1 . LEU A 1 123 ? 108.246 139.153 94.639  1.00 63.17  ? 123 LEU A CD1 1 
ATOM   981  C  CD2 . LEU A 1 123 ? 107.933 137.820 96.721  1.00 63.17  ? 123 LEU A CD2 1 
ATOM   982  N  N   . THR A 1 124 ? 112.665 136.043 94.437  1.00 58.19  ? 124 THR A N   1 
ATOM   983  C  CA  . THR A 1 124 ? 113.803 135.174 94.718  1.00 58.19  ? 124 THR A CA  1 
ATOM   984  C  C   . THR A 1 124 ? 115.121 135.890 94.455  1.00 58.19  ? 124 THR A C   1 
ATOM   985  O  O   . THR A 1 124 ? 116.072 135.760 95.234  1.00 58.19  ? 124 THR A O   1 
ATOM   986  C  CB  . THR A 1 124 ? 113.706 133.902 93.878  1.00 58.19  ? 124 THR A CB  1 
ATOM   987  O  OG1 . THR A 1 124 ? 112.457 133.253 94.144  1.00 58.19  ? 124 THR A OG1 1 
ATOM   988  C  CG2 . THR A 1 124 ? 114.845 132.952 94.215  1.00 58.19  ? 124 THR A CG2 1 
ATOM   989  N  N   . LEU A 1 125 ? 115.197 136.648 93.359  1.00 54.53  ? 125 LEU A N   1 
ATOM   990  C  CA  . LEU A 1 125 ? 116.405 137.421 93.080  1.00 54.53  ? 125 LEU A CA  1 
ATOM   991  C  C   . LEU A 1 125 ? 116.672 138.430 94.188  1.00 54.53  ? 125 LEU A C   1 
ATOM   992  O  O   . LEU A 1 125 ? 117.814 138.577 94.643  1.00 54.53  ? 125 LEU A O   1 
ATOM   993  C  CB  . LEU A 1 125 ? 116.281 138.133 91.731  1.00 54.53  ? 125 LEU A CB  1 
ATOM   994  C  CG  . LEU A 1 125 ? 117.560 138.553 90.994  1.00 54.53  ? 125 LEU A CG  1 
ATOM   995  C  CD1 . LEU A 1 125 ? 117.260 138.825 89.532  1.00 54.53  ? 125 LEU A CD1 1 
ATOM   996  C  CD2 . LEU A 1 125 ? 118.215 139.778 91.615  1.00 54.53  ? 125 LEU A CD2 1 
ATOM   997  N  N   . GLY A 1 126 ? 115.630 139.134 94.633  1.00 53.00  ? 126 GLY A N   1 
ATOM   998  C  CA  . GLY A 1 126 ? 115.808 140.102 95.701  1.00 53.00  ? 126 GLY A CA  1 
ATOM   999  C  C   . GLY A 1 126 ? 116.248 139.459 97.001  1.00 53.00  ? 126 GLY A C   1 
ATOM   1000 O  O   . GLY A 1 126 ? 117.119 139.983 97.700  1.00 53.00  ? 126 GLY A O   1 
ATOM   1001 N  N   . PHE A 1 127 ? 115.651 138.314 97.342  1.00 52.59  ? 127 PHE A N   1 
ATOM   1002 C  CA  . PHE A 1 127 ? 116.046 137.606 98.554  1.00 52.59  ? 127 PHE A CA  1 
ATOM   1003 C  C   . PHE A 1 127 ? 117.496 137.156 98.476  1.00 52.59  ? 127 PHE A C   1 
ATOM   1004 O  O   . PHE A 1 127 ? 118.248 137.298 99.445  1.00 52.59  ? 127 PHE A O   1 
ATOM   1005 C  CB  . PHE A 1 127 ? 115.137 136.401 98.796  1.00 52.59  ? 127 PHE A CB  1 
ATOM   1006 C  CG  . PHE A 1 127 ? 113.857 136.736 99.495  1.00 52.59  ? 127 PHE A CG  1 
ATOM   1007 C  CD1 . PHE A 1 127 ? 113.870 137.289 100.764 1.00 52.59  ? 127 PHE A CD1 1 
ATOM   1008 C  CD2 . PHE A 1 127 ? 112.638 136.467 98.900  1.00 52.59  ? 127 PHE A CD2 1 
ATOM   1009 C  CE1 . PHE A 1 127 ? 112.692 137.594 101.411 1.00 52.59  ? 127 PHE A CE1 1 
ATOM   1010 C  CE2 . PHE A 1 127 ? 111.456 136.766 99.544  1.00 52.59  ? 127 PHE A CE2 1 
ATOM   1011 C  CZ  . PHE A 1 127 ? 111.483 137.329 100.800 1.00 52.59  ? 127 PHE A CZ  1 
ATOM   1012 N  N   . MET A 1 128 ? 117.908 136.614 97.328  1.00 49.91  ? 128 MET A N   1 
ATOM   1013 C  CA  . MET A 1 128 ? 119.290 136.174 97.170  1.00 49.91  ? 128 MET A CA  1 
ATOM   1014 C  C   . MET A 1 128 ? 120.254 137.348 97.285  1.00 49.91  ? 128 MET A C   1 
ATOM   1015 O  O   . MET A 1 128 ? 121.288 137.251 97.955  1.00 49.91  ? 128 MET A O   1 
ATOM   1016 C  CB  . MET A 1 128 ? 119.461 135.459 95.830  1.00 49.91  ? 128 MET A CB  1 
ATOM   1017 C  CG  . MET A 1 128 ? 118.790 134.096 95.768  1.00 49.91  ? 128 MET A CG  1 
ATOM   1018 S  SD  . MET A 1 128 ? 119.478 133.021 94.495  1.00 49.91  ? 128 MET A SD  1 
ATOM   1019 C  CE  . MET A 1 128 ? 120.560 131.980 95.468  1.00 49.91  ? 128 MET A CE  1 
ATOM   1020 N  N   . SER A 1 129 ? 119.922 138.475 96.651  1.00 48.68  ? 129 SER A N   1 
ATOM   1021 C  CA  . SER A 1 129 ? 120.805 139.637 96.699  1.00 48.68  ? 129 SER A CA  1 
ATOM   1022 C  C   . SER A 1 129 ? 120.921 140.184 98.117  1.00 48.68  ? 129 SER A C   1 
ATOM   1023 O  O   . SER A 1 129 ? 122.025 140.473 98.596  1.00 48.68  ? 129 SER A O   1 
ATOM   1024 C  CB  . SER A 1 129 ? 120.297 140.715 95.743  1.00 48.68  ? 129 SER A CB  1 
ATOM   1025 O  OG  . SER A 1 129 ? 120.327 140.260 94.401  1.00 48.68  ? 129 SER A OG  1 
ATOM   1026 N  N   . SER A 1 130 ? 119.788 140.324 98.810  1.00 47.58  ? 130 SER A N   1 
ATOM   1027 C  CA  . SER A 1 130 ? 119.815 140.842 100.174 1.00 47.58  ? 130 SER A CA  1 
ATOM   1028 C  C   . SER A 1 130 ? 120.550 139.892 101.111 1.00 47.58  ? 130 SER A C   1 
ATOM   1029 O  O   . SER A 1 130 ? 121.316 140.335 101.975 1.00 47.58  ? 130 SER A O   1 
ATOM   1030 C  CB  . SER A 1 130 ? 118.392 141.093 100.668 1.00 47.58  ? 130 SER A CB  1 
ATOM   1031 O  OG  . SER A 1 130 ? 117.576 139.951 100.480 1.00 47.58  ? 130 SER A OG  1 
ATOM   1032 N  N   . THR A 1 131 ? 120.331 138.585 100.958 1.00 45.82  ? 131 THR A N   1 
ATOM   1033 C  CA  . THR A 1 131 ? 121.012 137.615 101.806 1.00 45.82  ? 131 THR A CA  1 
ATOM   1034 C  C   . THR A 1 131 ? 122.513 137.619 101.556 1.00 45.82  ? 131 THR A C   1 
ATOM   1035 O  O   . THR A 1 131 ? 123.301 137.520 102.501 1.00 45.82  ? 131 THR A O   1 
ATOM   1036 C  CB  . THR A 1 131 ? 120.429 136.223 101.575 1.00 45.82  ? 131 THR A CB  1 
ATOM   1037 O  OG1 . THR A 1 131 ? 118.999 136.297 101.597 1.00 45.82  ? 131 THR A OG1 1 
ATOM   1038 C  CG2 . THR A 1 131 ? 120.891 135.269 102.661 1.00 45.82  ? 131 THR A CG2 1 
ATOM   1039 N  N   . ALA A 1 132 ? 122.932 137.733 100.293 1.00 46.88  ? 132 ALA A N   1 
ATOM   1040 C  CA  . ALA A 1 132 ? 124.359 137.817 99.997  1.00 46.88  ? 132 ALA A CA  1 
ATOM   1041 C  C   . ALA A 1 132 ? 124.971 139.081 100.588 1.00 46.88  ? 132 ALA A C   1 
ATOM   1042 O  O   . ALA A 1 132 ? 126.064 139.039 101.167 1.00 46.88  ? 132 ALA A O   1 
ATOM   1043 C  CB  . ALA A 1 132 ? 124.586 137.766 98.488  1.00 46.88  ? 132 ALA A CB  1 
ATOM   1044 N  N   . PHE A 1 133 ? 124.276 140.215 100.462 1.00 48.42  ? 133 PHE A N   1 
ATOM   1045 C  CA  . PHE A 1 133 ? 124.795 141.457 101.025 1.00 48.42  ? 133 PHE A CA  1 
ATOM   1046 C  C   . PHE A 1 133 ? 124.908 141.368 102.542 1.00 48.42  ? 133 PHE A C   1 
ATOM   1047 O  O   . PHE A 1 133 ? 125.886 141.845 103.127 1.00 48.42  ? 133 PHE A O   1 
ATOM   1048 C  CB  . PHE A 1 133 ? 123.907 142.631 100.615 1.00 48.42  ? 133 PHE A CB  1 
ATOM   1049 C  CG  . PHE A 1 133 ? 124.612 143.959 100.632 1.00 48.42  ? 133 PHE A CG  1 
ATOM   1050 C  CD1 . PHE A 1 133 ? 124.986 144.549 101.828 1.00 48.42  ? 133 PHE A CD1 1 
ATOM   1051 C  CD2 . PHE A 1 133 ? 124.909 144.612 99.448  1.00 48.42  ? 133 PHE A CD2 1 
ATOM   1052 C  CE1 . PHE A 1 133 ? 125.638 145.766 101.843 1.00 48.42  ? 133 PHE A CE1 1 
ATOM   1053 C  CE2 . PHE A 1 133 ? 125.560 145.829 99.457  1.00 48.42  ? 133 PHE A CE2 1 
ATOM   1054 C  CZ  . PHE A 1 133 ? 125.924 146.407 100.656 1.00 48.42  ? 133 PHE A CZ  1 
ATOM   1055 N  N   . LEU A 1 134 ? 123.914 140.764 103.197 1.00 45.63  ? 134 LEU A N   1 
ATOM   1056 C  CA  . LEU A 1 134 ? 123.967 140.625 104.649 1.00 45.63  ? 134 LEU A CA  1 
ATOM   1057 C  C   . LEU A 1 134 ? 125.064 139.659 105.080 1.00 45.63  ? 134 LEU A C   1 
ATOM   1058 O  O   . LEU A 1 134 ? 125.775 139.917 106.058 1.00 45.63  ? 134 LEU A O   1 
ATOM   1059 C  CB  . LEU A 1 134 ? 122.608 140.173 105.181 1.00 45.63  ? 134 LEU A CB  1 
ATOM   1060 C  CG  . LEU A 1 134 ? 121.558 141.281 105.263 1.00 45.63  ? 134 LEU A CG  1 
ATOM   1061 C  CD1 . LEU A 1 134 ? 120.214 140.723 105.684 1.00 45.63  ? 134 LEU A CD1 1 
ATOM   1062 C  CD2 . LEU A 1 134 ? 122.016 142.362 106.227 1.00 45.63  ? 134 LEU A CD2 1 
ATOM   1063 N  N   . SER A 1 135 ? 125.220 138.543 104.366 1.00 45.77  ? 135 SER A N   1 
ATOM   1064 C  CA  . SER A 1 135 ? 126.249 137.569 104.701 1.00 45.77  ? 135 SER A CA  1 
ATOM   1065 C  C   . SER A 1 135 ? 127.647 138.042 104.342 1.00 45.77  ? 135 SER A C   1 
ATOM   1066 O  O   . SER A 1 135 ? 128.621 137.417 104.774 1.00 45.77  ? 135 SER A O   1 
ATOM   1067 C  CB  . SER A 1 135 ? 125.959 136.243 104.000 1.00 45.77  ? 135 SER A CB  1 
ATOM   1068 O  OG  . SER A 1 135 ? 126.968 135.289 104.278 1.00 45.77  ? 135 SER A OG  1 
ATOM   1069 N  N   . MET A 1 136 ? 127.768 139.106 103.546 1.00 48.45  ? 136 MET A N   1 
ATOM   1070 C  CA  . MET A 1 136 ? 129.078 139.705 103.310 1.00 48.45  ? 136 MET A CA  1 
ATOM   1071 C  C   . MET A 1 136 ? 129.755 140.079 104.623 1.00 48.45  ? 136 MET A C   1 
ATOM   1072 O  O   . MET A 1 136 ? 130.979 139.969 104.755 1.00 48.45  ? 136 MET A O   1 
ATOM   1073 C  CB  . MET A 1 136 ? 128.932 140.933 102.412 1.00 48.45  ? 136 MET A CB  1 
ATOM   1074 C  CG  . MET A 1 136 ? 130.133 141.219 101.532 1.00 48.45  ? 136 MET A CG  1 
ATOM   1075 S  SD  . MET A 1 136 ? 129.743 142.350 100.184 1.00 48.45  ? 136 MET A SD  1 
ATOM   1076 C  CE  . MET A 1 136 ? 129.022 141.224 98.994  1.00 48.45  ? 136 MET A CE  1 
ATOM   1077 N  N   . TRP A 1 137 ? 128.972 140.516 105.607 1.00 46.15  ? 137 TRP A N   1 
ATOM   1078 C  CA  . TRP A 1 137 ? 129.475 140.886 106.925 1.00 46.15  ? 137 TRP A CA  1 
ATOM   1079 C  C   . TRP A 1 137 ? 129.066 139.918 108.022 1.00 46.15  ? 137 TRP A C   1 
ATOM   1080 O  O   . TRP A 1 137 ? 129.892 139.569 108.867 1.00 46.15  ? 137 TRP A O   1 
ATOM   1081 C  CB  . TRP A 1 137 ? 128.995 142.294 107.291 1.00 46.15  ? 137 TRP A CB  1 
ATOM   1082 C  CG  . TRP A 1 137 ? 128.972 143.222 106.123 1.00 46.15  ? 137 TRP A CG  1 
ATOM   1083 C  CD1 . TRP A 1 137 ? 127.871 143.729 105.500 1.00 46.15  ? 137 TRP A CD1 1 
ATOM   1084 C  CD2 . TRP A 1 137 ? 130.106 143.751 105.428 1.00 46.15  ? 137 TRP A CD2 1 
ATOM   1085 N  NE1 . TRP A 1 137 ? 128.248 144.543 104.460 1.00 46.15  ? 137 TRP A NE1 1 
ATOM   1086 C  CE2 . TRP A 1 137 ? 129.616 144.573 104.395 1.00 46.15  ? 137 TRP A CE2 1 
ATOM   1087 C  CE3 . TRP A 1 137 ? 131.488 143.610 105.579 1.00 46.15  ? 137 TRP A CE3 1 
ATOM   1088 C  CZ2 . TRP A 1 137 ? 130.460 145.252 103.519 1.00 46.15  ? 137 TRP A CZ2 1 
ATOM   1089 C  CZ3 . TRP A 1 137 ? 132.323 144.284 104.710 1.00 46.15  ? 137 TRP A CZ3 1 
ATOM   1090 C  CH2 . TRP A 1 137 ? 131.807 145.094 103.693 1.00 46.15  ? 137 TRP A CH2 1 
ATOM   1091 N  N   . LEU A 1 138 ? 127.814 139.475 108.034 1.00 42.77  ? 138 LEU A N   1 
ATOM   1092 C  CA  . LEU A 1 138 ? 127.345 138.514 109.018 1.00 42.77  ? 138 LEU A CA  1 
ATOM   1093 C  C   . LEU A 1 138 ? 127.806 137.109 108.650 1.00 42.77  ? 138 LEU A C   1 
ATOM   1094 O  O   . LEU A 1 138 ? 128.100 136.807 107.492 1.00 42.77  ? 138 LEU A O   1 
ATOM   1095 C  CB  . LEU A 1 138 ? 125.820 138.547 109.127 1.00 42.77  ? 138 LEU A CB  1 
ATOM   1096 C  CG  . LEU A 1 138 ? 125.132 139.853 109.527 1.00 42.77  ? 138 LEU A CG  1 
ATOM   1097 C  CD1 . LEU A 1 138 ? 123.728 139.905 108.953 1.00 42.77  ? 138 LEU A CD1 1 
ATOM   1098 C  CD2 . LEU A 1 138 ? 125.087 139.993 111.036 1.00 42.77  ? 138 LEU A CD2 1 
ATOM   1099 N  N   . SER A 1 139 ? 127.866 136.245 109.658 1.00 41.30  ? 139 SER A N   1 
ATOM   1100 C  CA  . SER A 1 139 ? 128.134 134.839 109.402 1.00 41.30  ? 139 SER A CA  1 
ATOM   1101 C  C   . SER A 1 139 ? 126.933 134.199 108.715 1.00 41.30  ? 139 SER A C   1 
ATOM   1102 O  O   . SER A 1 139 ? 125.804 134.686 108.810 1.00 41.30  ? 139 SER A O   1 
ATOM   1103 C  CB  . SER A 1 139 ? 128.456 134.107 110.704 1.00 41.30  ? 139 SER A CB  1 
ATOM   1104 O  OG  . SER A 1 139 ? 127.367 134.162 111.606 1.00 41.30  ? 139 SER A OG  1 
ATOM   1105 N  N   . ASN A 1 140 ? 127.189 133.096 108.007 1.00 41.47  ? 140 ASN A N   1 
ATOM   1106 C  CA  . ASN A 1 140 ? 126.125 132.447 107.246 1.00 41.47  ? 140 ASN A CA  1 
ATOM   1107 C  C   . ASN A 1 140 ? 124.995 131.984 108.154 1.00 41.47  ? 140 ASN A C   1 
ATOM   1108 O  O   . ASN A 1 140 ? 123.815 132.147 107.821 1.00 41.47  ? 140 ASN A O   1 
ATOM   1109 C  CB  . ASN A 1 140 ? 126.687 131.267 106.457 1.00 41.47  ? 140 ASN A CB  1 
ATOM   1110 C  CG  . ASN A 1 140 ? 127.844 131.660 105.569 1.00 41.47  ? 140 ASN A CG  1 
ATOM   1111 O  OD1 . ASN A 1 140 ? 128.132 132.842 105.393 1.00 41.47  ? 140 ASN A OD1 1 
ATOM   1112 N  ND2 . ASN A 1 140 ? 128.512 130.666 104.998 1.00 41.47  ? 140 ASN A ND2 1 
ATOM   1113 N  N   . THR A 1 141 ? 125.336 131.400 109.304 1.00 37.31  ? 141 THR A N   1 
ATOM   1114 C  CA  . THR A 1 141 ? 124.315 130.960 110.249 1.00 37.31  ? 141 THR A CA  1 
ATOM   1115 C  C   . THR A 1 141 ? 123.486 132.138 110.745 1.00 37.31  ? 141 THR A C   1 
ATOM   1116 O  O   . THR A 1 141 ? 122.249 132.090 110.746 1.00 37.31  ? 141 THR A O   1 
ATOM   1117 C  CB  . THR A 1 141 ? 124.977 130.235 111.420 1.00 37.31  ? 141 THR A CB  1 
ATOM   1118 O  OG1 . THR A 1 141 ? 125.802 129.177 110.919 1.00 37.31  ? 141 THR A OG1 1 
ATOM   1119 C  CG2 . THR A 1 141 ? 123.933 129.659 112.355 1.00 37.31  ? 141 THR A CG2 1 
ATOM   1120 N  N   . SER A 1 142 ? 124.158 133.213 111.159 1.00 38.19  ? 142 SER A N   1 
ATOM   1121 C  CA  . SER A 1 142 ? 123.452 134.399 111.629 1.00 38.19  ? 142 SER A CA  1 
ATOM   1122 C  C   . SER A 1 142 ? 122.646 135.044 110.509 1.00 38.19  ? 142 SER A C   1 
ATOM   1123 O  O   . SER A 1 142 ? 121.521 135.505 110.734 1.00 38.19  ? 142 SER A O   1 
ATOM   1124 C  CB  . SER A 1 142 ? 124.446 135.395 112.220 1.00 38.19  ? 142 SER A CB  1 
ATOM   1125 O  OG  . SER A 1 142 ? 125.498 135.661 111.310 1.00 38.19  ? 142 SER A OG  1 
ATOM   1126 N  N   . THR A 1 143 ? 123.203 135.087 109.297 1.00 40.90  ? 143 THR A N   1 
ATOM   1127 C  CA  . THR A 1 143 ? 122.475 135.660 108.169 1.00 40.90  ? 143 THR A CA  1 
ATOM   1128 C  C   . THR A 1 143 ? 121.192 134.886 107.899 1.00 40.90  ? 143 THR A C   1 
ATOM   1129 O  O   . THR A 1 143 ? 120.127 135.479 107.700 1.00 40.90  ? 143 THR A O   1 
ATOM   1130 C  CB  . THR A 1 143 ? 123.360 135.677 106.923 1.00 40.90  ? 143 THR A CB  1 
ATOM   1131 O  OG1 . THR A 1 143 ? 124.580 136.368 107.211 1.00 40.90  ? 143 THR A OG1 1 
ATOM   1132 C  CG2 . THR A 1 143 ? 122.653 136.378 105.775 1.00 40.90  ? 143 THR A CG2 1 
ATOM   1133 N  N   . ALA A 1 144 ? 121.275 133.554 107.891 1.00 39.62  ? 144 ALA A N   1 
ATOM   1134 C  CA  . ALA A 1 144 ? 120.079 132.749 107.672 1.00 39.62  ? 144 ALA A CA  1 
ATOM   1135 C  C   . ALA A 1 144 ? 119.068 132.952 108.791 1.00 39.62  ? 144 ALA A C   1 
ATOM   1136 O  O   . ALA A 1 144 ? 117.870 133.125 108.532 1.00 39.62  ? 144 ALA A O   1 
ATOM   1137 C  CB  . ALA A 1 144 ? 120.454 131.273 107.544 1.00 39.62  ? 144 ALA A CB  1 
ATOM   1138 N  N   . ALA A 1 145 ? 119.536 132.962 110.043 1.00 38.56  ? 145 ALA A N   1 
ATOM   1139 C  CA  . ALA A 1 145 ? 118.626 133.134 111.171 1.00 38.56  ? 145 ALA A CA  1 
ATOM   1140 C  C   . ALA A 1 145 ? 117.914 134.478 111.107 1.00 38.56  ? 145 ALA A C   1 
ATOM   1141 O  O   . ALA A 1 145 ? 116.736 134.583 111.467 1.00 38.56  ? 145 ALA A O   1 
ATOM   1142 C  CB  . ALA A 1 145 ? 119.390 132.992 112.487 1.00 38.56  ? 145 ALA A CB  1 
ATOM   1143 N  N   . MET A 1 146 ? 118.615 135.520 110.658 1.00 38.04  ? 146 MET A N   1 
ATOM   1144 C  CA  . MET A 1 146 ? 118.000 136.838 110.543 1.00 38.04  ? 146 MET A CA  1 
ATOM   1145 C  C   . MET A 1 146 ? 117.019 136.898 109.377 1.00 38.04  ? 146 MET A C   1 
ATOM   1146 O  O   . MET A 1 146 ? 115.914 137.434 109.511 1.00 38.04  ? 146 MET A O   1 
ATOM   1147 C  CB  . MET A 1 146 ? 119.083 137.904 110.387 1.00 38.04  ? 146 MET A CB  1 
ATOM   1148 C  CG  . MET A 1 146 ? 119.928 138.120 111.626 1.00 38.04  ? 146 MET A CG  1 
ATOM   1149 S  SD  . MET A 1 146 ? 120.645 139.769 111.674 1.00 38.04  ? 146 MET A SD  1 
ATOM   1150 C  CE  . MET A 1 146 ? 119.213 140.764 111.286 1.00 38.04  ? 146 MET A CE  1 
ATOM   1151 N  N   . VAL A 1 147 ? 117.405 136.349 108.223 1.00 42.35  ? 147 VAL A N   1 
ATOM   1152 C  CA  . VAL A 1 147 ? 116.653 136.600 106.997 1.00 42.35  ? 147 VAL A CA  1 
ATOM   1153 C  C   . VAL A 1 147 ? 115.429 135.696 106.901 1.00 42.35  ? 147 VAL A C   1 
ATOM   1154 O  O   . VAL A 1 147 ? 114.355 136.138 106.476 1.00 42.35  ? 147 VAL A O   1 
ATOM   1155 C  CB  . VAL A 1 147 ? 117.570 136.446 105.771 1.00 42.35  ? 147 VAL A CB  1 
ATOM   1156 C  CG1 . VAL A 1 147 ? 116.769 136.570 104.487 1.00 42.35  ? 147 VAL A CG1 1 
ATOM   1157 C  CG2 . VAL A 1 147 ? 118.664 137.493 105.803 1.00 42.35  ? 147 VAL A CG2 1 
ATOM   1158 N  N   . MET A 1 148 ? 115.563 134.425 107.283 1.00 48.25  ? 148 MET A N   1 
ATOM   1159 C  CA  . MET A 1 148 ? 114.511 133.453 106.991 1.00 48.25  ? 148 MET A CA  1 
ATOM   1160 C  C   . MET A 1 148 ? 113.133 133.835 107.532 1.00 48.25  ? 148 MET A C   1 
ATOM   1161 O  O   . MET A 1 148 ? 112.144 133.608 106.813 1.00 48.25  ? 148 MET A O   1 
ATOM   1162 C  CB  . MET A 1 148 ? 114.941 132.070 107.498 1.00 48.25  ? 148 MET A CB  1 
ATOM   1163 C  CG  . MET A 1 148 ? 113.940 130.971 107.210 1.00 48.25  ? 148 MET A CG  1 
ATOM   1164 S  SD  . MET A 1 148 ? 113.735 130.653 105.450 1.00 48.25  ? 148 MET A SD  1 
ATOM   1165 C  CE  . MET A 1 148 ? 111.950 130.638 105.325 1.00 48.25  ? 148 MET A CE  1 
ATOM   1166 N  N   . PRO A 1 149 ? 112.979 134.377 108.751 1.00 45.01  ? 149 PRO A N   1 
ATOM   1167 C  CA  . PRO A 1 149 ? 111.635 134.816 109.176 1.00 45.01  ? 149 PRO A CA  1 
ATOM   1168 C  C   . PRO A 1 149 ? 110.990 135.821 108.236 1.00 45.01  ? 149 PRO A C   1 
ATOM   1169 O  O   . PRO A 1 149 ? 109.770 135.778 108.029 1.00 45.01  ? 149 PRO A O   1 
ATOM   1170 C  CB  . PRO A 1 149 ? 111.880 135.436 110.559 1.00 45.01  ? 149 PRO A CB  1 
ATOM   1171 C  CG  . PRO A 1 149 ? 113.193 134.952 111.011 1.00 45.01  ? 149 PRO A CG  1 
ATOM   1172 C  CD  . PRO A 1 149 ? 113.926 134.315 109.878 1.00 45.01  ? 149 PRO A CD  1 
ATOM   1173 N  N   . ILE A 1 150 ? 111.776 136.734 107.662 1.00 44.15  ? 150 ILE A N   1 
ATOM   1174 C  CA  . ILE A 1 150 ? 111.213 137.739 106.765 1.00 44.15  ? 150 ILE A CA  1 
ATOM   1175 C  C   . ILE A 1 150 ? 110.626 137.080 105.524 1.00 44.15  ? 150 ILE A C   1 
ATOM   1176 O  O   . ILE A 1 150 ? 109.517 137.415 105.089 1.00 44.15  ? 150 ILE A O   1 
ATOM   1177 C  CB  . ILE A 1 150 ? 112.279 138.788 106.403 1.00 44.15  ? 150 ILE A CB  1 
ATOM   1178 C  CG1 . ILE A 1 150 ? 112.940 139.328 107.671 1.00 44.15  ? 150 ILE A CG1 1 
ATOM   1179 C  CG2 . ILE A 1 150 ? 111.659 139.919 105.606 1.00 44.15  ? 150 ILE A CG2 1 
ATOM   1180 C  CD1 . ILE A 1 150 ? 114.097 140.259 107.407 1.00 44.15  ? 150 ILE A CD1 1 
ATOM   1181 N  N   . ALA A 1 151 ? 111.351 136.127 104.938 1.00 47.49  ? 151 ALA A N   1 
ATOM   1182 C  CA  . ALA A 1 151 ? 110.826 135.432 103.769 1.00 47.49  ? 151 ALA A CA  1 
ATOM   1183 C  C   . ALA A 1 151 ? 109.659 134.525 104.128 1.00 47.49  ? 151 ALA A C   1 
ATOM   1184 O  O   . ALA A 1 151 ? 108.758 134.323 103.306 1.00 47.49  ? 151 ALA A O   1 
ATOM   1185 C  CB  . ALA A 1 151 ? 111.926 134.625 103.095 1.00 47.49  ? 151 ALA A CB  1 
ATOM   1186 N  N   . GLU A 1 152 ? 109.664 133.958 105.336 1.00 51.23  ? 152 GLU A N   1 
ATOM   1187 C  CA  . GLU A 1 152 ? 108.500 133.210 105.795 1.00 51.23  ? 152 GLU A CA  1 
ATOM   1188 C  C   . GLU A 1 152 ? 107.271 134.106 105.824 1.00 51.23  ? 152 GLU A C   1 
ATOM   1189 O  O   . GLU A 1 152 ? 106.196 133.721 105.349 1.00 51.23  ? 152 GLU A O   1 
ATOM   1190 C  CB  . GLU A 1 152 ? 108.769 132.622 107.180 1.00 51.23  ? 152 GLU A CB  1 
ATOM   1191 C  CG  . GLU A 1 152 ? 107.651 131.767 107.786 1.00 51.23  ? 152 GLU A CG  1 
ATOM   1192 C  CD  . GLU A 1 152 ? 107.066 130.733 106.831 1.00 51.23  ? 152 GLU A CD  1 
ATOM   1193 O  OE1 . GLU A 1 152 ? 107.329 129.532 107.043 1.00 51.23  ? 152 GLU A OE1 1 
ATOM   1194 O  OE2 . GLU A 1 152 ? 106.314 131.096 105.904 1.00 51.23  ? 152 GLU A OE2 1 
ATOM   1195 N  N   . ALA A 1 153 ? 107.423 135.321 106.354 1.00 49.56  ? 153 ALA A N   1 
ATOM   1196 C  CA  . ALA A 1 153 ? 106.324 136.280 106.336 1.00 49.56  ? 153 ALA A CA  1 
ATOM   1197 C  C   . ALA A 1 153 ? 105.909 136.611 104.908 1.00 49.56  ? 153 ALA A C   1 
ATOM   1198 O  O   . ALA A 1 153 ? 104.711 136.674 104.602 1.00 49.56  ? 153 ALA A O   1 
ATOM   1199 C  CB  . ALA A 1 153 ? 106.722 137.549 107.088 1.00 49.56  ? 153 ALA A CB  1 
ATOM   1200 N  N   . VAL A 1 154 ? 106.887 136.807 104.018 1.00 51.44  ? 154 VAL A N   1 
ATOM   1201 C  CA  . VAL A 1 154 ? 106.580 137.136 102.627 1.00 51.44  ? 154 VAL A CA  1 
ATOM   1202 C  C   . VAL A 1 154 ? 105.715 136.052 102.002 1.00 51.44  ? 154 VAL A C   1 
ATOM   1203 O  O   . VAL A 1 154 ? 104.634 136.325 101.466 1.00 51.44  ? 154 VAL A O   1 
ATOM   1204 C  CB  . VAL A 1 154 ? 107.874 137.334 101.816 1.00 51.44  ? 154 VAL A CB  1 
ATOM   1205 C  CG1 . VAL A 1 154 ? 107.563 137.338 100.332 1.00 51.44  ? 154 VAL A CG1 1 
ATOM   1206 C  CG2 . VAL A 1 154 ? 108.560 138.622 102.193 1.00 51.44  ? 154 VAL A CG2 1 
ATOM   1207 N  N   . VAL A 1 155 ? 106.162 134.800 102.091 1.00 56.55  ? 155 VAL A N   1 
ATOM   1208 C  CA  . VAL A 1 155 ? 105.446 133.725 101.416 1.00 56.55  ? 155 VAL A CA  1 
ATOM   1209 C  C   . VAL A 1 155 ? 104.091 133.490 102.074 1.00 56.55  ? 155 VAL A C   1 
ATOM   1210 O  O   . VAL A 1 155 ? 103.093 133.235 101.389 1.00 56.55  ? 155 VAL A O   1 
ATOM   1211 C  CB  . VAL A 1 155 ? 106.301 132.443 101.366 1.00 56.55  ? 155 VAL A CB  1 
ATOM   1212 C  CG1 . VAL A 1 155 ? 107.577 132.689 100.569 1.00 56.55  ? 155 VAL A CG1 1 
ATOM   1213 C  CG2 . VAL A 1 155 ? 106.634 131.944 102.760 1.00 56.55  ? 155 VAL A CG2 1 
ATOM   1214 N  N   . GLN A 1 156 ? 104.020 133.590 103.404 1.00 63.40  ? 156 GLN A N   1 
ATOM   1215 C  CA  . GLN A 1 156 ? 102.738 133.402 104.068 1.00 63.40  ? 156 GLN A CA  1 
ATOM   1216 C  C   . GLN A 1 156 ? 101.737 134.447 103.597 1.00 63.40  ? 156 GLN A C   1 
ATOM   1217 O  O   . GLN A 1 156 ? 100.578 134.124 103.310 1.00 63.40  ? 156 GLN A O   1 
ATOM   1218 C  CB  . GLN A 1 156 ? 102.916 133.464 105.586 1.00 63.40  ? 156 GLN A CB  1 
ATOM   1219 C  CG  . GLN A 1 156 ? 101.656 133.203 106.425 1.00 63.40  ? 156 GLN A CG  1 
ATOM   1220 C  CD  . GLN A 1 156 ? 100.684 132.181 105.832 1.00 63.40  ? 156 GLN A CD  1 
ATOM   1221 O  OE1 . GLN A 1 156 ? 101.075 131.250 105.125 1.00 63.40  ? 156 GLN A OE1 1 
ATOM   1222 N  NE2 . GLN A 1 156 ? 99.405  132.352 106.136 1.00 63.40  ? 156 GLN A NE2 1 
ATOM   1223 N  N   . GLN A 1 157 ? 102.179 135.702 103.475 1.00 64.84  ? 157 GLN A N   1 
ATOM   1224 C  CA  . GLN A 1 157 ? 101.301 136.744 102.955 1.00 64.84  ? 157 GLN A CA  1 
ATOM   1225 C  C   . GLN A 1 157 ? 100.917 136.479 101.503 1.00 64.84  ? 157 GLN A C   1 
ATOM   1226 O  O   . GLN A 1 157 ? 99.791  136.780 101.094 1.00 64.84  ? 157 GLN A O   1 
ATOM   1227 C  CB  . GLN A 1 157 ? 101.967 138.112 103.100 1.00 64.84  ? 157 GLN A CB  1 
ATOM   1228 C  CG  . GLN A 1 157 ? 102.201 138.538 104.543 1.00 64.84  ? 157 GLN A CG  1 
ATOM   1229 C  CD  . GLN A 1 157 ? 100.931 138.546 105.370 1.00 64.84  ? 157 GLN A CD  1 
ATOM   1230 O  OE1 . GLN A 1 157 ? 100.924 138.104 106.519 1.00 64.84  ? 157 GLN A OE1 1 
ATOM   1231 N  NE2 . GLN A 1 157 ? 99.849  139.055 104.792 1.00 64.84  ? 157 GLN A NE2 1 
ATOM   1232 N  N   . ILE A 1 158 ? 101.836 135.924 100.706 1.00 64.88  ? 158 ILE A N   1 
ATOM   1233 C  CA  . ILE A 1 158 ? 101.513 135.640 99.306  1.00 64.88  ? 158 ILE A CA  1 
ATOM   1234 C  C   . ILE A 1 158 ? 100.400 134.601 99.202  1.00 64.88  ? 158 ILE A C   1 
ATOM   1235 O  O   . ILE A 1 158 ? 99.415  134.802 98.479  1.00 64.88  ? 158 ILE A O   1 
ATOM   1236 C  CB  . ILE A 1 158 ? 102.769 135.205 98.527  1.00 64.88  ? 158 ILE A CB  1 
ATOM   1237 C  CG1 . ILE A 1 158 ? 103.835 136.299 98.569  1.00 64.88  ? 158 ILE A CG1 1 
ATOM   1238 C  CG2 . ILE A 1 158 ? 102.419 134.876 97.085  1.00 64.88  ? 158 ILE A CG2 1 
ATOM   1239 C  CD1 . ILE A 1 158 ? 103.394 137.602 97.943  1.00 64.88  ? 158 ILE A CD1 1 
ATOM   1240 N  N   . ILE A 1 159 ? 100.530 133.479 99.917  1.00 68.47  ? 159 ILE A N   1 
ATOM   1241 C  CA  . ILE A 1 159 ? 99.451  132.486 99.891  1.00 68.47  ? 159 ILE A CA  1 
ATOM   1242 C  C   . ILE A 1 159 ? 98.166  133.048 100.495 1.00 68.47  ? 159 ILE A C   1 
ATOM   1243 O  O   . ILE A 1 159 ? 97.066  132.739 100.021 1.00 68.47  ? 159 ILE A O   1 
ATOM   1244 C  CB  . ILE A 1 159 ? 99.862  131.144 100.539 1.00 68.47  ? 159 ILE A CB  1 
ATOM   1245 C  CG1 . ILE A 1 159 ? 100.993 130.444 99.768  1.00 68.47  ? 159 ILE A CG1 1 
ATOM   1246 C  CG2 . ILE A 1 159 ? 98.672  130.203 100.652 1.00 68.47  ? 159 ILE A CG2 1 
ATOM   1247 C  CD1 . ILE A 1 159 ? 102.386 130.768 100.139 1.00 68.47  ? 159 ILE A CD1 1 
ATOM   1248 N  N   . ASN A 1 160 ? 98.269  133.889 101.528 1.00 70.40  ? 160 ASN A N   1 
ATOM   1249 C  CA  . ASN A 1 160 ? 97.058  134.510 102.063 1.00 70.40  ? 160 ASN A CA  1 
ATOM   1250 C  C   . ASN A 1 160 ? 96.348  135.341 101.000 1.00 70.40  ? 160 ASN A C   1 
ATOM   1251 O  O   . ASN A 1 160 ? 95.123  135.242 100.833 1.00 70.40  ? 160 ASN A O   1 
ATOM   1252 C  CB  . ASN A 1 160 ? 97.395  135.381 103.273 1.00 70.40  ? 160 ASN A CB  1 
ATOM   1253 C  CG  . ASN A 1 160 ? 97.809  134.569 104.479 1.00 70.40  ? 160 ASN A CG  1 
ATOM   1254 O  OD1 . ASN A 1 160 ? 97.215  133.534 104.779 1.00 70.40  ? 160 ASN A OD1 1 
ATOM   1255 N  ND2 . ASN A 1 160 ? 98.828  135.042 105.187 1.00 70.40  ? 160 ASN A ND2 1 
ATOM   1256 N  N   . ALA A 1 161 ? 97.106  136.155 100.263 1.00 74.93  ? 161 ALA A N   1 
ATOM   1257 C  CA  . ALA A 1 161 ? 96.518  137.001 99.231  1.00 74.93  ? 161 ALA A CA  1 
ATOM   1258 C  C   . ALA A 1 161 ? 95.896  136.164 98.123  1.00 74.93  ? 161 ALA A C   1 
ATOM   1259 O  O   . ALA A 1 161 ? 94.789  136.457 97.657  1.00 74.93  ? 161 ALA A O   1 
ATOM   1260 C  CB  . ALA A 1 161 ? 97.576  137.945 98.663  1.00 74.93  ? 161 ALA A CB  1 
ATOM   1261 N  N   . GLU A 1 162 ? 96.596  135.115 97.681  1.00 77.43  ? 162 GLU A N   1 
ATOM   1262 C  CA  . GLU A 1 162 ? 96.038  134.270 96.628  1.00 77.43  ? 162 GLU A CA  1 
ATOM   1263 C  C   . GLU A 1 162 ? 94.764  133.573 97.086  1.00 77.43  ? 162 GLU A C   1 
ATOM   1264 O  O   . GLU A 1 162 ? 93.783  133.521 96.334  1.00 77.43  ? 162 GLU A O   1 
ATOM   1265 C  CB  . GLU A 1 162 ? 97.065  133.235 96.158  1.00 77.43  ? 162 GLU A CB  1 
ATOM   1266 C  CG  . GLU A 1 162 ? 98.469  133.762 95.823  1.00 77.43  ? 162 GLU A CG  1 
ATOM   1267 C  CD  . GLU A 1 162 ? 98.525  134.894 94.796  1.00 77.43  ? 162 GLU A CD  1 
ATOM   1268 O  OE1 . GLU A 1 162 ? 99.650  135.220 94.366  1.00 77.43  ? 162 GLU A OE1 1 
ATOM   1269 O  OE2 . GLU A 1 162 ? 97.478  135.434 94.380  1.00 77.43  ? 162 GLU A OE2 1 
ATOM   1270 N  N   . ALA A 1 163 ? 94.752  133.048 98.315  1.00 81.12  ? 163 ALA A N   1 
ATOM   1271 C  CA  . ALA A 1 163 ? 93.564  132.366 98.817  1.00 81.12  ? 163 ALA A CA  1 
ATOM   1272 C  C   . ALA A 1 163 ? 92.385  133.321 98.932  1.00 81.12  ? 163 ALA A C   1 
ATOM   1273 O  O   . ALA A 1 163 ? 91.257  132.967 98.571  1.00 81.12  ? 163 ALA A O   1 
ATOM   1274 C  CB  . ALA A 1 163 ? 93.863  131.719 100.168 1.00 81.12  ? 163 ALA A CB  1 
ATOM   1275 N  N   . GLU A 1 164 ? 92.619  134.536 99.433  1.00 83.84  ? 164 GLU A N   1 
ATOM   1276 C  CA  . GLU A 1 164 ? 91.507  135.468 99.583  1.00 83.84  ? 164 GLU A CA  1 
ATOM   1277 C  C   . GLU A 1 164 ? 91.020  136.005 98.241  1.00 83.84  ? 164 GLU A C   1 
ATOM   1278 O  O   . GLU A 1 164 ? 89.813  136.209 98.066  1.00 83.84  ? 164 GLU A O   1 
ATOM   1279 C  CB  . GLU A 1 164 ? 91.896  136.618 100.511 1.00 83.84  ? 164 GLU A CB  1 
ATOM   1280 C  CG  . GLU A 1 164 ? 90.771  137.613 100.740 1.00 83.84  ? 164 GLU A CG  1 
ATOM   1281 C  CD  . GLU A 1 164 ? 91.270  139.032 100.866 1.00 83.84  ? 164 GLU A CD  1 
ATOM   1282 O  OE1 . GLU A 1 164 ? 92.407  139.210 101.343 1.00 83.84  ? 164 GLU A OE1 1 
ATOM   1283 O  OE2 . GLU A 1 164 ? 90.531  139.964 100.487 1.00 83.84  ? 164 GLU A OE2 1 
ATOM   1284 N  N   . VAL A 1 165 ? 91.926  136.239 97.288  1.00 83.81  ? 165 VAL A N   1 
ATOM   1285 C  CA  . VAL A 1 165 ? 91.504  136.672 95.958  1.00 83.81  ? 165 VAL A CA  1 
ATOM   1286 C  C   . VAL A 1 165 ? 90.691  135.579 95.277  1.00 83.81  ? 165 VAL A C   1 
ATOM   1287 O  O   . VAL A 1 165 ? 89.658  135.851 94.652  1.00 83.81  ? 165 VAL A O   1 
ATOM   1288 C  CB  . VAL A 1 165 ? 92.726  137.084 95.116  1.00 83.81  ? 165 VAL A CB  1 
ATOM   1289 C  CG1 . VAL A 1 165 ? 92.364  137.148 93.641  1.00 83.81  ? 165 VAL A CG1 1 
ATOM   1290 C  CG2 . VAL A 1 165 ? 93.260  138.427 95.587  1.00 83.81  ? 165 VAL A CG2 1 
ATOM   1291 N  N   . GLU A 1 166 ? 91.139  134.325 95.390  1.00 87.90  ? 166 GLU A N   1 
ATOM   1292 C  CA  . GLU A 1 166 ? 90.378  133.217 94.822  1.00 87.90  ? 166 GLU A CA  1 
ATOM   1293 C  C   . GLU A 1 166 ? 89.011  133.093 95.482  1.00 87.90  ? 166 GLU A C   1 
ATOM   1294 O  O   . GLU A 1 166 ? 88.009  132.826 94.808  1.00 87.90  ? 166 GLU A O   1 
ATOM   1295 C  CB  . GLU A 1 166 ? 91.163  131.913 94.963  1.00 87.90  ? 166 GLU A CB  1 
ATOM   1296 C  CG  . GLU A 1 166 ? 92.256  131.730 93.922  1.00 87.90  ? 166 GLU A CG  1 
ATOM   1297 C  CD  . GLU A 1 166 ? 93.143  130.534 94.211  1.00 87.90  ? 166 GLU A CD  1 
ATOM   1298 O  OE1 . GLU A 1 166 ? 93.128  130.043 95.359  1.00 87.90  ? 166 GLU A OE1 1 
ATOM   1299 O  OE2 . GLU A 1 166 ? 93.857  130.086 93.289  1.00 87.90  ? 166 GLU A OE2 1 
ATOM   1300 N  N   . ALA A 1 167 ? 88.950  133.279 96.796  1.00 86.27  ? 167 ALA A N   1 
ATOM   1301 C  CA  . ALA A 1 167 ? 87.684  133.233 97.517  1.00 86.27  ? 167 ALA A CA  1 
ATOM   1302 C  C   . ALA A 1 167 ? 86.939  134.558 97.387  1.00 86.27  ? 167 ALA A C   1 
ATOM   1303 O  O   . ALA A 1 167 ? 86.623  134.998 96.281  1.00 86.27  ? 167 ALA A O   1 
ATOM   1304 C  CB  . ALA A 1 167 ? 87.919  132.897 98.981  1.00 86.27  ? 167 ALA A CB  1 
ATOM   1305 N  N   . THR A 1 230 ? 98.380  125.665 99.081  1.00 83.06  ? 230 THR A N   1 
ATOM   1306 C  CA  . THR A 1 230 ? 98.311  125.019 97.776  1.00 83.06  ? 230 THR A CA  1 
ATOM   1307 C  C   . THR A 1 230 ? 99.658  124.416 97.391  1.00 83.06  ? 230 THR A C   1 
ATOM   1308 O  O   . THR A 1 230 ? 100.672 124.675 98.039  1.00 83.06  ? 230 THR A O   1 
ATOM   1309 C  CB  . THR A 1 230 ? 97.869  126.006 96.679  1.00 83.06  ? 230 THR A CB  1 
ATOM   1310 O  OG1 . THR A 1 230 ? 98.764  127.125 96.649  1.00 83.06  ? 230 THR A OG1 1 
ATOM   1311 C  CG2 . THR A 1 230 ? 96.456  126.500 96.944  1.00 83.06  ? 230 THR A CG2 1 
ATOM   1312 N  N   . LYS A 1 231 ? 99.656  123.599 96.336  1.00 80.45  ? 231 LYS A N   1 
ATOM   1313 C  CA  . LYS A 1 231 ? 100.899 122.997 95.864  1.00 80.45  ? 231 LYS A CA  1 
ATOM   1314 C  C   . LYS A 1 231 ? 101.859 124.053 95.326  1.00 80.45  ? 231 LYS A C   1 
ATOM   1315 O  O   . LYS A 1 231 ? 103.069 123.979 95.567  1.00 80.45  ? 231 LYS A O   1 
ATOM   1316 C  CB  . LYS A 1 231 ? 100.599 121.946 94.797  1.00 80.45  ? 231 LYS A CB  1 
ATOM   1317 C  CG  . LYS A 1 231 ? 99.424  121.043 95.135  1.00 80.45  ? 231 LYS A CG  1 
ATOM   1318 C  CD  . LYS A 1 231 ? 99.030  120.179 93.948  1.00 80.45  ? 231 LYS A CD  1 
ATOM   1319 C  CE  . LYS A 1 231 ? 100.080 119.119 93.662  1.00 80.45  ? 231 LYS A CE  1 
ATOM   1320 N  NZ  . LYS A 1 231 ? 100.129 118.085 94.732  1.00 80.45  ? 231 LYS A NZ  1 
ATOM   1321 N  N   . LYS A 1 232 ? 101.338 125.037 94.587  1.00 75.86  ? 232 LYS A N   1 
ATOM   1322 C  CA  . LYS A 1 232 ? 102.192 126.096 94.059  1.00 75.86  ? 232 LYS A CA  1 
ATOM   1323 C  C   . LYS A 1 232 ? 102.818 126.913 95.182  1.00 75.86  ? 232 LYS A C   1 
ATOM   1324 O  O   . LYS A 1 232 ? 104.010 127.244 95.130  1.00 75.86  ? 232 LYS A O   1 
ATOM   1325 C  CB  . LYS A 1 232 ? 101.392 126.999 93.118  1.00 75.86  ? 232 LYS A CB  1 
ATOM   1326 C  CG  . LYS A 1 232 ? 100.544 126.252 92.097  1.00 75.86  ? 232 LYS A CG  1 
ATOM   1327 C  CD  . LYS A 1 232 ? 99.094  126.130 92.544  1.00 75.86  ? 232 LYS A CD  1 
ATOM   1328 C  CE  . LYS A 1 232 ? 98.221  125.572 91.432  1.00 75.86  ? 232 LYS A CE  1 
ATOM   1329 N  NZ  . LYS A 1 232 ? 96.841  125.275 91.904  1.00 75.86  ? 232 LYS A NZ  1 
ATOM   1330 N  N   . GLY A 1 233 ? 102.033 127.247 96.207  1.00 70.07  ? 233 GLY A N   1 
ATOM   1331 C  CA  . GLY A 1 233 ? 102.588 127.958 97.347  1.00 70.07  ? 233 GLY A CA  1 
ATOM   1332 C  C   . GLY A 1 233 ? 103.636 127.147 98.083  1.00 70.07  ? 233 GLY A C   1 
ATOM   1333 O  O   . GLY A 1 233 ? 104.655 127.684 98.523  1.00 70.07  ? 233 GLY A O   1 
ATOM   1334 N  N   . HIS A 1 234 ? 103.401 125.842 98.226  1.00 69.23  ? 234 HIS A N   1 
ATOM   1335 C  CA  . HIS A 1 234 ? 104.381 124.974 98.871  1.00 69.23  ? 234 HIS A CA  1 
ATOM   1336 C  C   . HIS A 1 234 ? 105.682 124.927 98.077  1.00 69.23  ? 234 HIS A C   1 
ATOM   1337 O  O   . HIS A 1 234 ? 106.777 124.982 98.654  1.00 69.23  ? 234 HIS A O   1 
ATOM   1338 C  CB  . HIS A 1 234 ? 103.786 123.576 99.042  1.00 69.23  ? 234 HIS A CB  1 
ATOM   1339 C  CG  . HIS A 1 234 ? 104.807 122.493 99.189  1.00 69.23  ? 234 HIS A CG  1 
ATOM   1340 N  ND1 . HIS A 1 234 ? 105.143 121.644 98.157  1.00 69.23  ? 234 HIS A ND1 1 
ATOM   1341 C  CD2 . HIS A 1 234 ? 105.554 122.110 100.251 1.00 69.23  ? 234 HIS A CD2 1 
ATOM   1342 C  CE1 . HIS A 1 234 ? 106.059 120.789 98.575  1.00 69.23  ? 234 HIS A CE1 1 
ATOM   1343 N  NE2 . HIS A 1 234 ? 106.325 121.050 99.842  1.00 69.23  ? 234 HIS A NE2 1 
ATOM   1344 N  N   . VAL A 1 235 ? 105.581 124.836 96.749  1.00 66.27  ? 235 VAL A N   1 
ATOM   1345 C  CA  . VAL A 1 235 ? 106.771 124.844 95.903  1.00 66.27  ? 235 VAL A CA  1 
ATOM   1346 C  C   . VAL A 1 235 ? 107.506 126.172 96.033  1.00 66.27  ? 235 VAL A C   1 
ATOM   1347 O  O   . VAL A 1 235 ? 108.742 126.214 96.088  1.00 66.27  ? 235 VAL A O   1 
ATOM   1348 C  CB  . VAL A 1 235 ? 106.386 124.544 94.442  1.00 66.27  ? 235 VAL A CB  1 
ATOM   1349 C  CG1 . VAL A 1 235 ? 107.513 124.928 93.498  1.00 66.27  ? 235 VAL A CG1 1 
ATOM   1350 C  CG2 . VAL A 1 235 ? 106.030 123.076 94.280  1.00 66.27  ? 235 VAL A CG2 1 
ATOM   1351 N  N   . THR A 1 236 ? 106.759 127.277 96.082  1.00 62.73  ? 236 THR A N   1 
ATOM   1352 C  CA  . THR A 1 236 ? 107.384 128.586 96.245  1.00 62.73  ? 236 THR A CA  1 
ATOM   1353 C  C   . THR A 1 236 ? 108.117 128.690 97.578  1.00 62.73  ? 236 THR A C   1 
ATOM   1354 O  O   . THR A 1 236 ? 109.225 129.236 97.644  1.00 62.73  ? 236 THR A O   1 
ATOM   1355 C  CB  . THR A 1 236 ? 106.334 129.689 96.124  1.00 62.73  ? 236 THR A CB  1 
ATOM   1356 O  OG1 . THR A 1 236 ? 105.530 129.457 94.961  1.00 62.73  ? 236 THR A OG1 1 
ATOM   1357 C  CG2 . THR A 1 236 ? 107.002 131.050 96.008  1.00 62.73  ? 236 THR A CG2 1 
ATOM   1358 N  N   . ARG A 1 237 ? 107.510 128.181 98.653  1.00 61.19  ? 237 ARG A N   1 
ATOM   1359 C  CA  . ARG A 1 237 ? 108.179 128.193 99.952  1.00 61.19  ? 237 ARG A CA  1 
ATOM   1360 C  C   . ARG A 1 237 ? 109.447 127.349 99.928  1.00 61.19  ? 237 ARG A C   1 
ATOM   1361 O  O   . ARG A 1 237 ? 110.480 127.753 100.477 1.00 61.19  ? 237 ARG A O   1 
ATOM   1362 C  CB  . ARG A 1 237 ? 107.231 127.704 101.047 1.00 61.19  ? 237 ARG A CB  1 
ATOM   1363 C  CG  . ARG A 1 237 ? 105.960 128.522 101.183 1.00 61.19  ? 237 ARG A CG  1 
ATOM   1364 C  CD  . ARG A 1 237 ? 104.857 127.730 101.863 1.00 61.19  ? 237 ARG A CD  1 
ATOM   1365 N  NE  . ARG A 1 237 ? 104.672 128.128 103.253 1.00 61.19  ? 237 ARG A NE  1 
ATOM   1366 C  CZ  . ARG A 1 237 ? 103.654 127.745 104.011 1.00 61.19  ? 237 ARG A CZ  1 
ATOM   1367 N  NH1 . ARG A 1 237 ? 102.709 126.945 103.547 1.00 61.19  ? 237 ARG A NH1 1 
ATOM   1368 N  NH2 . ARG A 1 237 ? 103.582 128.177 105.267 1.00 61.19  ? 237 ARG A NH2 1 
ATOM   1369 N  N   . LYS A 1 238 ? 109.387 126.172 99.299  1.00 58.04  ? 238 LYS A N   1 
ATOM   1370 C  CA  . LYS A 1 238 ? 110.581 125.341 99.167  1.00 58.04  ? 238 LYS A CA  1 
ATOM   1371 C  C   . LYS A 1 238 ? 111.688 126.088 98.434  1.00 58.04  ? 238 LYS A C   1 
ATOM   1372 O  O   . LYS A 1 238 ? 112.848 126.102 98.871  1.00 58.04  ? 238 LYS A O   1 
ATOM   1373 C  CB  . LYS A 1 238 ? 110.237 124.050 98.425  1.00 58.04  ? 238 LYS A CB  1 
ATOM   1374 C  CG  . LYS A 1 238 ? 109.654 122.953 99.287  1.00 58.04  ? 238 LYS A CG  1 
ATOM   1375 C  CD  . LYS A 1 238 ? 109.448 121.692 98.468  1.00 58.04  ? 238 LYS A CD  1 
ATOM   1376 C  CE  . LYS A 1 238 ? 109.482 120.453 99.341  1.00 58.04  ? 238 LYS A CE  1 
ATOM   1377 N  NZ  . LYS A 1 238 ? 109.281 119.220 98.535  1.00 58.04  ? 238 LYS A NZ  1 
ATOM   1378 N  N   . LEU A 1 239 ? 111.340 126.717 97.310  1.00 55.30  ? 239 LEU A N   1 
ATOM   1379 C  CA  . LEU A 1 239 ? 112.333 127.426 96.514  1.00 55.30  ? 239 LEU A CA  1 
ATOM   1380 C  C   . LEU A 1 239 ? 112.932 128.591 97.290  1.00 55.30  ? 239 LEU A C   1 
ATOM   1381 O  O   . LEU A 1 239 ? 114.145 128.819 97.236  1.00 55.30  ? 239 LEU A O   1 
ATOM   1382 C  CB  . LEU A 1 239 ? 111.702 127.906 95.208  1.00 55.30  ? 239 LEU A CB  1 
ATOM   1383 C  CG  . LEU A 1 239 ? 112.620 128.545 94.166  1.00 55.30  ? 239 LEU A CG  1 
ATOM   1384 C  CD1 . LEU A 1 239 ? 112.195 128.126 92.775  1.00 55.30  ? 239 LEU A CD1 1 
ATOM   1385 C  CD2 . LEU A 1 239 ? 112.591 130.056 94.285  1.00 55.30  ? 239 LEU A CD2 1 
ATOM   1386 N  N   . THR A 1 240 ? 112.099 129.339 98.016  1.00 54.12  ? 240 THR A N   1 
ATOM   1387 C  CA  . THR A 1 240 ? 112.605 130.464 98.795  1.00 54.12  ? 240 THR A CA  1 
ATOM   1388 C  C   . THR A 1 240 ? 113.532 129.992 99.909  1.00 54.12  ? 240 THR A C   1 
ATOM   1389 O  O   . THR A 1 240 ? 114.591 130.588 100.146 1.00 54.12  ? 240 THR A O   1 
ATOM   1390 C  CB  . THR A 1 240 ? 111.441 131.270 99.369  1.00 54.12  ? 240 THR A CB  1 
ATOM   1391 O  OG1 . THR A 1 240 ? 110.613 131.741 98.299  1.00 54.12  ? 240 THR A OG1 1 
ATOM   1392 C  CG2 . THR A 1 240 ? 111.955 132.460 100.156 1.00 54.12  ? 240 THR A CG2 1 
ATOM   1393 N  N   . CYS A 1 241 ? 113.154 128.915 100.599 1.00 51.60  ? 241 CYS A N   1 
ATOM   1394 C  CA  . CYS A 1 241 ? 114.005 128.378 101.655 1.00 51.60  ? 241 CYS A CA  1 
ATOM   1395 C  C   . CYS A 1 241 ? 115.360 127.957 101.100 1.00 51.60  ? 241 CYS A C   1 
ATOM   1396 O  O   . CYS A 1 241 ? 116.412 128.304 101.656 1.00 51.60  ? 241 CYS A O   1 
ATOM   1397 C  CB  . CYS A 1 241 ? 113.303 127.200 102.329 1.00 51.60  ? 241 CYS A CB  1 
ATOM   1398 S  SG  . CYS A 1 241 ? 111.875 127.646 103.341 1.00 51.60  ? 241 CYS A SG  1 
ATOM   1399 N  N   . LEU A 1 242 ? 115.354 127.223 99.984  1.00 48.52  ? 242 LEU A N   1 
ATOM   1400 C  CA  . LEU A 1 242 ? 116.610 126.769 99.398  1.00 48.52  ? 242 LEU A CA  1 
ATOM   1401 C  C   . LEU A 1 242 ? 117.456 127.939 98.912  1.00 48.52  ? 242 LEU A C   1 
ATOM   1402 O  O   . LEU A 1 242 ? 118.683 127.938 99.081  1.00 48.52  ? 242 LEU A O   1 
ATOM   1403 C  CB  . LEU A 1 242 ? 116.337 125.793 98.256  1.00 48.52  ? 242 LEU A CB  1 
ATOM   1404 C  CG  . LEU A 1 242 ? 116.281 124.324 98.671  1.00 48.52  ? 242 LEU A CG  1 
ATOM   1405 C  CD1 . LEU A 1 242 ? 115.939 123.445 97.487  1.00 48.52  ? 242 LEU A CD1 1 
ATOM   1406 C  CD2 . LEU A 1 242 ? 117.596 123.898 99.301  1.00 48.52  ? 242 LEU A CD2 1 
ATOM   1407 N  N   . CYS A 1 243 ? 116.824 128.944 98.297  1.00 48.56  ? 243 CYS A N   1 
ATOM   1408 C  CA  . CYS A 1 243 ? 117.588 130.076 97.791  1.00 48.56  ? 243 CYS A CA  1 
ATOM   1409 C  C   . CYS A 1 243 ? 118.229 130.853 98.931  1.00 48.56  ? 243 CYS A C   1 
ATOM   1410 O  O   . CYS A 1 243 ? 119.377 131.290 98.813  1.00 48.56  ? 243 CYS A O   1 
ATOM   1411 C  CB  . CYS A 1 243 ? 116.704 130.990 96.942  1.00 48.56  ? 243 CYS A CB  1 
ATOM   1412 S  SG  . CYS A 1 243 ? 115.711 132.183 97.857  1.00 48.56  ? 243 CYS A SG  1 
ATOM   1413 N  N   . ILE A 1 244 ? 117.517 131.022 100.048 1.00 46.50  ? 244 ILE A N   1 
ATOM   1414 C  CA  . ILE A 1 244 ? 118.122 131.676 101.208 1.00 46.50  ? 244 ILE A CA  1 
ATOM   1415 C  C   . ILE A 1 244 ? 119.299 130.860 101.723 1.00 46.50  ? 244 ILE A C   1 
ATOM   1416 O  O   . ILE A 1 244 ? 120.386 131.397 101.985 1.00 46.50  ? 244 ILE A O   1 
ATOM   1417 C  CB  . ILE A 1 244 ? 117.077 131.892 102.314 1.00 46.50  ? 244 ILE A CB  1 
ATOM   1418 C  CG1 . ILE A 1 244 ? 115.978 132.830 101.835 1.00 46.50  ? 244 ILE A CG1 1 
ATOM   1419 C  CG2 . ILE A 1 244 ? 117.739 132.442 103.569 1.00 46.50  ? 244 ILE A CG2 1 
ATOM   1420 C  CD1 . ILE A 1 244 ? 114.822 132.865 102.768 1.00 46.50  ? 244 ILE A CD1 1 
ATOM   1421 N  N   . ALA A 1 245 ? 119.100 129.545 101.869 1.00 42.92  ? 245 ALA A N   1 
ATOM   1422 C  CA  . ALA A 1 245 ? 120.151 128.697 102.423 1.00 42.92  ? 245 ALA A CA  1 
ATOM   1423 C  C   . ALA A 1 245 ? 121.414 128.762 101.579 1.00 42.92  ? 245 ALA A C   1 
ATOM   1424 O  O   . ALA A 1 245 ? 122.525 128.848 102.114 1.00 42.92  ? 245 ALA A O   1 
ATOM   1425 C  CB  . ALA A 1 245 ? 119.662 127.255 102.532 1.00 42.92  ? 245 ALA A CB  1 
ATOM   1426 N  N   . TYR A 1 246 ? 121.265 128.723 100.256 1.00 42.53  ? 246 TYR A N   1 
ATOM   1427 C  CA  . TYR A 1 246 ? 122.439 128.776 99.393  1.00 42.53  ? 246 TYR A CA  1 
ATOM   1428 C  C   . TYR A 1 246 ? 123.047 130.175 99.354  1.00 42.53  ? 246 TYR A C   1 
ATOM   1429 O  O   . TYR A 1 246 ? 124.264 130.330 99.513  1.00 42.53  ? 246 TYR A O   1 
ATOM   1430 C  CB  . TYR A 1 246 ? 122.072 128.306 97.986  1.00 42.53  ? 246 TYR A CB  1 
ATOM   1431 C  CG  . TYR A 1 246 ? 121.632 126.859 97.923  1.00 42.53  ? 246 TYR A CG  1 
ATOM   1432 C  CD1 . TYR A 1 246 ? 121.855 125.997 98.988  1.00 42.53  ? 246 TYR A CD1 1 
ATOM   1433 C  CD2 . TYR A 1 246 ? 120.989 126.357 96.802  1.00 42.53  ? 246 TYR A CD2 1 
ATOM   1434 C  CE1 . TYR A 1 246 ? 121.454 124.679 98.938  1.00 42.53  ? 246 TYR A CE1 1 
ATOM   1435 C  CE2 . TYR A 1 246 ? 120.584 125.038 96.743  1.00 42.53  ? 246 TYR A CE2 1 
ATOM   1436 C  CZ  . TYR A 1 246 ? 120.820 124.205 97.814  1.00 42.53  ? 246 TYR A CZ  1 
ATOM   1437 O  OH  . TYR A 1 246 ? 120.421 122.891 97.765  1.00 42.53  ? 246 TYR A OH  1 
ATOM   1438 N  N   . SER A 1 247 ? 122.213 131.207 99.189  1.00 43.04  ? 247 SER A N   1 
ATOM   1439 C  CA  . SER A 1 247 ? 122.716 132.562 99.013  1.00 43.04  ? 247 SER A CA  1 
ATOM   1440 C  C   . SER A 1 247 ? 123.423 133.073 100.257 1.00 43.04  ? 247 SER A C   1 
ATOM   1441 O  O   . SER A 1 247 ? 124.312 133.922 100.146 1.00 43.04  ? 247 SER A O   1 
ATOM   1442 C  CB  . SER A 1 247 ? 121.570 133.496 98.637  1.00 43.04  ? 247 SER A CB  1 
ATOM   1443 O  OG  . SER A 1 247 ? 120.647 133.612 99.703  1.00 43.04  ? 247 SER A OG  1 
ATOM   1444 N  N   . SER A 1 248 ? 123.056 132.575 101.440 1.00 43.20  ? 248 SER A N   1 
ATOM   1445 C  CA  . SER A 1 248 ? 123.800 132.947 102.639 1.00 43.20  ? 248 SER A CA  1 
ATOM   1446 C  C   . SER A 1 248 ? 125.276 132.588 102.494 1.00 43.20  ? 248 SER A C   1 
ATOM   1447 O  O   . SER A 1 248 ? 126.157 133.441 102.654 1.00 43.20  ? 248 SER A O   1 
ATOM   1448 C  CB  . SER A 1 248 ? 123.189 132.264 103.862 1.00 43.20  ? 248 SER A CB  1 
ATOM   1449 O  OG  . SER A 1 248 ? 123.752 132.766 105.059 1.00 43.20  ? 248 SER A OG  1 
ATOM   1450 N  N   . THR A 1 249 ? 125.562 131.334 102.138 1.00 42.81  ? 249 THR A N   1 
ATOM   1451 C  CA  . THR A 1 249 ? 126.949 130.926 101.937 1.00 42.81  ? 249 THR A CA  1 
ATOM   1452 C  C   . THR A 1 249 ? 127.575 131.646 100.750 1.00 42.81  ? 249 THR A C   1 
ATOM   1453 O  O   . THR A 1 249 ? 128.754 132.019 100.797 1.00 42.81  ? 249 THR A O   1 
ATOM   1454 C  CB  . THR A 1 249 ? 127.029 129.415 101.738 1.00 42.81  ? 249 THR A CB  1 
ATOM   1455 O  OG1 . THR A 1 249 ? 126.384 129.066 100.509 1.00 42.81  ? 249 THR A OG1 1 
ATOM   1456 C  CG2 . THR A 1 249 ? 126.337 128.698 102.879 1.00 42.81  ? 249 THR A CG2 1 
ATOM   1457 N  N   . ILE A 1 250 ? 126.809 131.836 99.671  1.00 44.56  ? 250 ILE A N   1 
ATOM   1458 C  CA  . ILE A 1 250 ? 127.363 132.490 98.485  1.00 44.56  ? 250 ILE A CA  1 
ATOM   1459 C  C   . ILE A 1 250 ? 127.846 133.892 98.830  1.00 44.56  ? 250 ILE A C   1 
ATOM   1460 O  O   . ILE A 1 250 ? 128.924 134.318 98.398  1.00 44.56  ? 250 ILE A O   1 
ATOM   1461 C  CB  . ILE A 1 250 ? 126.333 132.515 97.342  1.00 44.56  ? 250 ILE A CB  1 
ATOM   1462 C  CG1 . ILE A 1 250 ? 125.781 131.115 97.091  1.00 44.56  ? 250 ILE A CG1 1 
ATOM   1463 C  CG2 . ILE A 1 250 ? 126.953 133.085 96.080  1.00 44.56  ? 250 ILE A CG2 1 
ATOM   1464 C  CD1 . ILE A 1 250 ? 126.720 130.208 96.367  1.00 44.56  ? 250 ILE A CD1 1 
ATOM   1465 N  N   . GLY A 1 251 ? 127.055 134.633 99.605  1.00 44.63  ? 251 GLY A N   1 
ATOM   1466 C  CA  . GLY A 1 251 ? 127.515 135.921 100.094 1.00 44.63  ? 251 GLY A CA  1 
ATOM   1467 C  C   . GLY A 1 251 ? 128.674 135.791 101.063 1.00 44.63  ? 251 GLY A C   1 
ATOM   1468 O  O   . GLY A 1 251 ? 129.564 136.644 101.096 1.00 44.63  ? 251 GLY A O   1 
ATOM   1469 N  N   . GLY A 1 252 ? 128.677 134.726 101.866 1.00 45.81  ? 252 GLY A N   1 
ATOM   1470 C  CA  . GLY A 1 252 ? 129.756 134.519 102.816 1.00 45.81  ? 252 GLY A CA  1 
ATOM   1471 C  C   . GLY A 1 252 ? 131.120 134.328 102.185 1.00 45.81  ? 252 GLY A C   1 
ATOM   1472 O  O   . GLY A 1 252 ? 132.125 134.743 102.770 1.00 45.81  ? 252 GLY A O   1 
ATOM   1473 N  N   . LEU A 1 253 ? 131.182 133.702 101.007 1.00 48.10  ? 253 LEU A N   1 
ATOM   1474 C  CA  . LEU A 1 253 ? 132.480 133.511 100.352 1.00 48.10  ? 253 LEU A CA  1 
ATOM   1475 C  C   . LEU A 1 253 ? 133.163 134.822 99.983  1.00 48.10  ? 253 LEU A C   1 
ATOM   1476 O  O   . LEU A 1 253 ? 134.362 134.816 99.685  1.00 48.10  ? 253 LEU A O   1 
ATOM   1477 C  CB  . LEU A 1 253 ? 132.374 132.660 99.078  1.00 48.10  ? 253 LEU A CB  1 
ATOM   1478 C  CG  . LEU A 1 253 ? 132.248 131.133 99.042  1.00 48.10  ? 253 LEU A CG  1 
ATOM   1479 C  CD1 . LEU A 1 253 ? 130.923 130.617 99.497  1.00 48.10  ? 253 LEU A CD1 1 
ATOM   1480 C  CD2 . LEU A 1 253 ? 132.510 130.656 97.625  1.00 48.10  ? 253 LEU A CD2 1 
ATOM   1481 N  N   . THR A 1 254 ? 132.438 135.940 99.988  1.00 52.33  ? 254 THR A N   1 
ATOM   1482 C  CA  . THR A 1 254 ? 132.989 137.177 99.444  1.00 52.33  ? 254 THR A CA  1 
ATOM   1483 C  C   . THR A 1 254 ? 134.058 137.798 100.339 1.00 52.33  ? 254 THR A C   1 
ATOM   1484 O  O   . THR A 1 254 ? 135.002 138.410 99.827  1.00 52.33  ? 254 THR A O   1 
ATOM   1485 C  CB  . THR A 1 254 ? 131.865 138.179 99.196  1.00 52.33  ? 254 THR A CB  1 
ATOM   1486 O  OG1 . THR A 1 254 ? 131.217 138.481 100.437 1.00 52.33  ? 254 THR A OG1 1 
ATOM   1487 C  CG2 . THR A 1 254 ? 130.853 137.608 98.220  1.00 52.33  ? 254 THR A CG2 1 
ATOM   1488 N  N   . THR A 1 255 ? 133.938 137.672 101.660 1.00 53.21  ? 255 THR A N   1 
ATOM   1489 C  CA  . THR A 1 255 ? 134.806 138.405 102.572 1.00 53.21  ? 255 THR A CA  1 
ATOM   1490 C  C   . THR A 1 255 ? 135.456 137.467 103.580 1.00 53.21  ? 255 THR A C   1 
ATOM   1491 O  O   . THR A 1 255 ? 135.027 136.328 103.775 1.00 53.21  ? 255 THR A O   1 
ATOM   1492 C  CB  . THR A 1 255 ? 134.041 139.502 103.324 1.00 53.21  ? 255 THR A CB  1 
ATOM   1493 O  OG1 . THR A 1 255 ? 132.873 138.941 103.936 1.00 53.21  ? 255 THR A OG1 1 
ATOM   1494 C  CG2 . THR A 1 255 ? 133.629 140.615 102.373 1.00 53.21  ? 255 THR A CG2 1 
ATOM   1495 N  N   . ILE A 1 256 ? 136.514 137.977 104.219 1.00 54.12  ? 256 ILE A N   1 
ATOM   1496 C  CA  . ILE A 1 256 ? 137.193 137.232 105.277 1.00 54.12  ? 256 ILE A CA  1 
ATOM   1497 C  C   . ILE A 1 256 ? 136.263 137.017 106.463 1.00 54.12  ? 256 ILE A C   1 
ATOM   1498 O  O   . ILE A 1 256 ? 136.166 135.910 107.005 1.00 54.12  ? 256 ILE A O   1 
ATOM   1499 C  CB  . ILE A 1 256 ? 138.480 137.962 105.703 1.00 54.12  ? 256 ILE A CB  1 
ATOM   1500 C  CG1 . ILE A 1 256 ? 139.441 138.111 104.524 1.00 54.12  ? 256 ILE A CG1 1 
ATOM   1501 C  CG2 . ILE A 1 256 ? 139.160 137.220 106.840 1.00 54.12  ? 256 ILE A CG2 1 
ATOM   1502 C  CD1 . ILE A 1 256 ? 139.907 136.796 103.959 1.00 54.12  ? 256 ILE A CD1 1 
ATOM   1503 N  N   . THR A 1 257 ? 135.567 138.068 106.887 1.00 50.53  ? 257 THR A N   1 
ATOM   1504 C  CA  . THR A 1 257 ? 134.691 137.983 108.048 1.00 50.53  ? 257 THR A CA  1 
ATOM   1505 C  C   . THR A 1 257 ? 133.297 137.478 107.705 1.00 50.53  ? 257 THR A C   1 
ATOM   1506 O  O   . THR A 1 257 ? 132.475 137.318 108.613 1.00 50.53  ? 257 THR A O   1 
ATOM   1507 C  CB  . THR A 1 257 ? 134.588 139.349 108.732 1.00 50.53  ? 257 THR A CB  1 
ATOM   1508 O  OG1 . THR A 1 257 ? 133.650 140.170 108.026 1.00 50.53  ? 257 THR A OG1 1 
ATOM   1509 C  CG2 . THR A 1 257 ? 135.943 140.037 108.748 1.00 50.53  ? 257 THR A CG2 1 
ATOM   1510 N  N   . GLY A 1 258 ? 133.009 137.230 106.427 1.00 45.40  ? 258 GLY A N   1 
ATOM   1511 C  CA  . GLY A 1 258 ? 131.700 136.714 106.064 1.00 45.40  ? 258 GLY A CA  1 
ATOM   1512 C  C   . GLY A 1 258 ? 131.441 135.333 106.632 1.00 45.40  ? 258 GLY A C   1 
ATOM   1513 O  O   . GLY A 1 258 ? 130.327 135.028 107.064 1.00 45.40  ? 258 GLY A O   1 
ATOM   1514 N  N   . THR A 1 259 ? 132.462 134.480 106.636 1.00 49.45  ? 259 THR A N   1 
ATOM   1515 C  CA  . THR A 1 259 ? 132.369 133.134 107.179 1.00 49.45  ? 259 THR A CA  1 
ATOM   1516 C  C   . THR A 1 259 ? 133.518 132.896 108.145 1.00 49.45  ? 259 THR A C   1 
ATOM   1517 O  O   . THR A 1 259 ? 134.614 133.436 107.977 1.00 49.45  ? 259 THR A O   1 
ATOM   1518 C  CB  . THR A 1 259 ? 132.416 132.062 106.081 1.00 49.45  ? 259 THR A CB  1 
ATOM   1519 O  OG1 . THR A 1 259 ? 133.683 132.115 105.415 1.00 49.45  ? 259 THR A OG1 1 
ATOM   1520 C  CG2 . THR A 1 259 ? 131.318 132.279 105.069 1.00 49.45  ? 259 THR A CG2 1 
ATOM   1521 N  N   . SER A 1 260 ? 133.256 132.078 109.165 1.00 47.64  ? 260 SER A N   1 
ATOM   1522 C  CA  . SER A 1 260 ? 134.329 131.651 110.053 1.00 47.64  ? 260 SER A CA  1 
ATOM   1523 C  C   . SER A 1 260 ? 135.334 130.757 109.342 1.00 47.64  ? 260 SER A C   1 
ATOM   1524 O  O   . SER A 1 260 ? 136.473 130.638 109.804 1.00 47.64  ? 260 SER A O   1 
ATOM   1525 C  CB  . SER A 1 260 ? 133.749 130.935 111.272 1.00 47.64  ? 260 SER A CB  1 
ATOM   1526 O  OG  . SER A 1 260 ? 132.944 129.840 110.880 1.00 47.64  ? 260 SER A OG  1 
ATOM   1527 N  N   . THR A 1 261 ? 134.938 130.128 108.232 1.00 48.31  ? 261 THR A N   1 
ATOM   1528 C  CA  . THR A 1 261 ? 135.882 129.349 107.436 1.00 48.31  ? 261 THR A CA  1 
ATOM   1529 C  C   . THR A 1 261 ? 137.004 130.231 106.904 1.00 48.31  ? 261 THR A C   1 
ATOM   1530 O  O   . THR A 1 261 ? 138.187 129.875 106.982 1.00 48.31  ? 261 THR A O   1 
ATOM   1531 C  CB  . THR A 1 261 ? 135.146 128.668 106.281 1.00 48.31  ? 261 THR A CB  1 
ATOM   1532 O  OG1 . THR A 1 261 ? 134.167 127.762 106.801 1.00 48.31  ? 261 THR A OG1 1 
ATOM   1533 C  CG2 . THR A 1 261 ? 136.119 127.906 105.400 1.00 48.31  ? 261 THR A CG2 1 
ATOM   1534 N  N   . ASN A 1 262 ? 136.645 131.398 106.365 1.00 51.81  ? 262 ASN A N   1 
ATOM   1535 C  CA  . ASN A 1 262 ? 137.651 132.321 105.855 1.00 51.81  ? 262 ASN A CA  1 
ATOM   1536 C  C   . ASN A 1 262 ? 138.543 132.834 106.976 1.00 51.81  ? 262 ASN A C   1 
ATOM   1537 O  O   . ASN A 1 262 ? 139.755 132.980 106.793 1.00 51.81  ? 262 ASN A O   1 
ATOM   1538 C  CB  . ASN A 1 262 ? 136.977 133.482 105.125 1.00 51.81  ? 262 ASN A CB  1 
ATOM   1539 C  CG  . ASN A 1 262 ? 136.188 133.031 103.913 1.00 51.81  ? 262 ASN A CG  1 
ATOM   1540 O  OD1 . ASN A 1 262 ? 136.530 132.041 103.269 1.00 51.81  ? 262 ASN A OD1 1 
ATOM   1541 N  ND2 . ASN A 1 262 ? 135.123 133.757 103.598 1.00 51.81  ? 262 ASN A ND2 1 
ATOM   1542 N  N   . LEU A 1 263 ? 137.962 133.115 108.145 1.00 54.45  ? 263 LEU A N   1 
ATOM   1543 C  CA  . LEU A 1 263 ? 138.764 133.566 109.279 1.00 54.45  ? 263 LEU A CA  1 
ATOM   1544 C  C   . LEU A 1 263 ? 139.756 132.495 109.716 1.00 54.45  ? 263 LEU A C   1 
ATOM   1545 O  O   . LEU A 1 263 ? 140.924 132.796 109.993 1.00 54.45  ? 263 LEU A O   1 
ATOM   1546 C  CB  . LEU A 1 263 ? 137.855 133.957 110.443 1.00 54.45  ? 263 LEU A CB  1 
ATOM   1547 C  CG  . LEU A 1 263 ? 137.028 135.230 110.266 1.00 54.45  ? 263 LEU A CG  1 
ATOM   1548 C  CD1 . LEU A 1 263 ? 136.014 135.373 111.388 1.00 54.45  ? 263 LEU A CD1 1 
ATOM   1549 C  CD2 . LEU A 1 263 ? 137.936 136.445 110.207 1.00 54.45  ? 263 LEU A CD2 1 
ATOM   1550 N  N   . ILE A 1 264 ? 139.308 131.240 109.785 1.00 53.04  ? 264 ILE A N   1 
ATOM   1551 C  CA  . ILE A 1 264 ? 140.193 130.151 110.190 1.00 53.04  ? 264 ILE A CA  1 
ATOM   1552 C  C   . ILE A 1 264 ? 141.322 129.984 109.183 1.00 53.04  ? 264 ILE A C   1 
ATOM   1553 O  O   . ILE A 1 264 ? 142.496 129.848 109.552 1.00 53.04  ? 264 ILE A O   1 
ATOM   1554 C  CB  . ILE A 1 264 ? 139.394 128.847 110.363 1.00 53.04  ? 264 ILE A CB  1 
ATOM   1555 C  CG1 . ILE A 1 264 ? 138.509 128.927 111.607 1.00 53.04  ? 264 ILE A CG1 1 
ATOM   1556 C  CG2 . ILE A 1 264 ? 140.330 127.653 110.447 1.00 53.04  ? 264 ILE A CG2 1 
ATOM   1557 C  CD1 . ILE A 1 264 ? 137.487 127.821 111.697 1.00 53.04  ? 264 ILE A CD1 1 
ATOM   1558 N  N   . PHE A 1 265 ? 140.985 130.001 107.891 1.00 58.41  ? 265 PHE A N   1 
ATOM   1559 C  CA  . PHE A 1 265 ? 142.017 129.867 106.869 1.00 58.41  ? 265 PHE A CA  1 
ATOM   1560 C  C   . PHE A 1 265 ? 143.002 131.027 106.923 1.00 58.41  ? 265 PHE A C   1 
ATOM   1561 O  O   . PHE A 1 265 ? 144.214 130.828 106.789 1.00 58.41  ? 265 PHE A O   1 
ATOM   1562 C  CB  . PHE A 1 265 ? 141.380 129.770 105.484 1.00 58.41  ? 265 PHE A CB  1 
ATOM   1563 C  CG  . PHE A 1 265 ? 142.293 130.192 104.371 1.00 58.41  ? 265 PHE A CG  1 
ATOM   1564 C  CD1 . PHE A 1 265 ? 143.370 129.406 104.007 1.00 58.41  ? 265 PHE A CD1 1 
ATOM   1565 C  CD2 . PHE A 1 265 ? 142.075 131.377 103.691 1.00 58.41  ? 265 PHE A CD2 1 
ATOM   1566 C  CE1 . PHE A 1 265 ? 144.213 129.794 102.988 1.00 58.41  ? 265 PHE A CE1 1 
ATOM   1567 C  CE2 . PHE A 1 265 ? 142.915 131.766 102.670 1.00 58.41  ? 265 PHE A CE2 1 
ATOM   1568 C  CZ  . PHE A 1 265 ? 143.984 130.975 102.318 1.00 58.41  ? 265 PHE A CZ  1 
ATOM   1569 N  N   . ALA A 1 266 ? 142.500 132.249 107.120 1.00 62.21  ? 266 ALA A N   1 
ATOM   1570 C  CA  . ALA A 1 266 ? 143.376 133.412 107.166 1.00 62.21  ? 266 ALA A CA  1 
ATOM   1571 C  C   . ALA A 1 266 ? 144.319 133.350 108.358 1.00 62.21  ? 266 ALA A C   1 
ATOM   1572 O  O   . ALA A 1 266 ? 145.517 133.627 108.222 1.00 62.21  ? 266 ALA A O   1 
ATOM   1573 C  CB  . ALA A 1 266 ? 142.544 134.693 107.206 1.00 62.21  ? 266 ALA A CB  1 
ATOM   1574 N  N   . GLU A 1 267 ? 143.804 132.987 109.536 1.00 65.18  ? 267 GLU A N   1 
ATOM   1575 C  CA  . GLU A 1 267 ? 144.672 132.916 110.706 1.00 65.18  ? 267 GLU A CA  1 
ATOM   1576 C  C   . GLU A 1 267 ? 145.694 131.796 110.560 1.00 65.18  ? 267 GLU A C   1 
ATOM   1577 O  O   . GLU A 1 267 ? 146.859 131.963 110.942 1.00 65.18  ? 267 GLU A O   1 
ATOM   1578 C  CB  . GLU A 1 267 ? 143.835 132.778 111.988 1.00 65.18  ? 267 GLU A CB  1 
ATOM   1579 C  CG  . GLU A 1 267 ? 142.936 131.542 112.136 1.00 65.18  ? 267 GLU A CG  1 
ATOM   1580 C  CD  . GLU A 1 267 ? 143.674 130.258 112.494 1.00 65.18  ? 267 GLU A CD  1 
ATOM   1581 O  OE1 . GLU A 1 267 ? 144.877 130.314 112.821 1.00 65.18  ? 267 GLU A OE1 1 
ATOM   1582 O  OE2 . GLU A 1 267 ? 143.041 129.183 112.448 1.00 65.18  ? 267 GLU A OE2 1 
ATOM   1583 N  N   . TYR A 1 268 ? 145.290 130.655 109.991 1.00 64.24  ? 268 TYR A N   1 
ATOM   1584 C  CA  . TYR A 1 268 ? 146.244 129.573 109.773 1.00 64.24  ? 268 TYR A CA  1 
ATOM   1585 C  C   . TYR A 1 268 ? 147.336 129.987 108.795 1.00 64.24  ? 268 TYR A C   1 
ATOM   1586 O  O   . TYR A 1 268 ? 148.521 129.712 109.023 1.00 64.24  ? 268 TYR A O   1 
ATOM   1587 C  CB  . TYR A 1 268 ? 145.521 128.326 109.268 1.00 64.24  ? 268 TYR A CB  1 
ATOM   1588 C  CG  . TYR A 1 268 ? 146.436 127.146 109.039 1.00 64.24  ? 268 TYR A CG  1 
ATOM   1589 C  CD1 . TYR A 1 268 ? 146.829 126.332 110.092 1.00 64.24  ? 268 TYR A CD1 1 
ATOM   1590 C  CD2 . TYR A 1 268 ? 146.909 126.847 107.769 1.00 64.24  ? 268 TYR A CD2 1 
ATOM   1591 C  CE1 . TYR A 1 268 ? 147.666 125.254 109.886 1.00 64.24  ? 268 TYR A CE1 1 
ATOM   1592 C  CE2 . TYR A 1 268 ? 147.746 125.772 107.554 1.00 64.24  ? 268 TYR A CE2 1 
ATOM   1593 C  CZ  . TYR A 1 268 ? 148.121 124.979 108.616 1.00 64.24  ? 268 TYR A CZ  1 
ATOM   1594 O  OH  . TYR A 1 268 ? 148.955 123.905 108.405 1.00 64.24  ? 268 TYR A OH  1 
ATOM   1595 N  N   . PHE A 1 269 ? 146.958 130.650 107.700 1.00 70.95  ? 269 PHE A N   1 
ATOM   1596 C  CA  . PHE A 1 269 ? 147.946 131.081 106.718 1.00 70.95  ? 269 PHE A CA  1 
ATOM   1597 C  C   . PHE A 1 269 ? 148.890 132.121 107.307 1.00 70.95  ? 269 PHE A C   1 
ATOM   1598 O  O   . PHE A 1 269 ? 150.098 132.087 107.049 1.00 70.95  ? 269 PHE A O   1 
ATOM   1599 C  CB  . PHE A 1 269 ? 147.247 131.631 105.476 1.00 70.95  ? 269 PHE A CB  1 
ATOM   1600 C  CG  . PHE A 1 269 ? 148.179 131.930 104.339 1.00 70.95  ? 269 PHE A CG  1 
ATOM   1601 C  CD1 . PHE A 1 269 ? 148.651 130.912 103.529 1.00 70.95  ? 269 PHE A CD1 1 
ATOM   1602 C  CD2 . PHE A 1 269 ? 148.587 133.227 104.083 1.00 70.95  ? 269 PHE A CD2 1 
ATOM   1603 C  CE1 . PHE A 1 269 ? 149.509 131.182 102.483 1.00 70.95  ? 269 PHE A CE1 1 
ATOM   1604 C  CE2 . PHE A 1 269 ? 149.447 133.503 103.038 1.00 70.95  ? 269 PHE A CE2 1 
ATOM   1605 C  CZ  . PHE A 1 269 ? 149.908 132.480 102.237 1.00 70.95  ? 269 PHE A CZ  1 
ATOM   1606 N  N   . ASN A 1 270 ? 148.356 133.055 108.097 1.00 72.92  ? 270 ASN A N   1 
ATOM   1607 C  CA  . ASN A 1 270 ? 149.202 134.065 108.723 1.00 72.92  ? 270 ASN A CA  1 
ATOM   1608 C  C   . ASN A 1 270 ? 150.172 133.436 109.714 1.00 72.92  ? 270 ASN A C   1 
ATOM   1609 O  O   . ASN A 1 270 ? 151.352 133.803 109.756 1.00 72.92  ? 270 ASN A O   1 
ATOM   1610 C  CB  . ASN A 1 270 ? 148.335 135.115 109.416 1.00 72.92  ? 270 ASN A CB  1 
ATOM   1611 C  CG  . ASN A 1 270 ? 147.566 135.973 108.435 1.00 72.92  ? 270 ASN A CG  1 
ATOM   1612 O  OD1 . ASN A 1 270 ? 147.816 135.934 107.230 1.00 72.92  ? 270 ASN A OD1 1 
ATOM   1613 N  ND2 . ASN A 1 270 ? 146.622 136.755 108.945 1.00 72.92  ? 270 ASN A ND2 1 
ATOM   1614 N  N   . THR A 1 271 ? 149.696 132.484 110.520 1.00 72.62  ? 271 THR A N   1 
ATOM   1615 C  CA  . THR A 1 271 ? 150.558 131.863 111.518 1.00 72.62  ? 271 THR A CA  1 
ATOM   1616 C  C   . THR A 1 271 ? 151.637 131.009 110.864 1.00 72.62  ? 271 THR A C   1 
ATOM   1617 O  O   . THR A 1 271 ? 152.810 131.070 111.251 1.00 72.62  ? 271 THR A O   1 
ATOM   1618 C  CB  . THR A 1 271 ? 149.722 131.025 112.485 1.00 72.62  ? 271 THR A CB  1 
ATOM   1619 O  OG1 . THR A 1 271 ? 148.636 131.814 112.988 1.00 72.62  ? 271 THR A OG1 1 
ATOM   1620 C  CG2 . THR A 1 271 ? 150.574 130.548 113.649 1.00 72.62  ? 271 THR A CG2 1 
ATOM   1621 N  N   . ARG A 1 272 ? 151.262 130.204 109.868 1.00 74.80  ? 272 ARG A N   1 
ATOM   1622 C  CA  . ARG A 1 272 ? 152.224 129.295 109.254 1.00 74.80  ? 272 ARG A CA  1 
ATOM   1623 C  C   . ARG A 1 272 ? 153.172 130.007 108.297 1.00 74.80  ? 272 ARG A C   1 
ATOM   1624 O  O   . ARG A 1 272 ? 154.306 129.553 108.108 1.00 74.80  ? 272 ARG A O   1 
ATOM   1625 C  CB  . ARG A 1 272 ? 151.495 128.169 108.524 1.00 74.80  ? 272 ARG A CB  1 
ATOM   1626 C  CG  . ARG A 1 272 ? 152.227 126.841 108.570 1.00 74.80  ? 272 ARG A CG  1 
ATOM   1627 C  CD  . ARG A 1 272 ? 151.750 125.908 107.476 1.00 74.80  ? 272 ARG A CD  1 
ATOM   1628 N  NE  . ARG A 1 272 ? 152.400 124.606 107.550 1.00 74.80  ? 272 ARG A NE  1 
ATOM   1629 C  CZ  . ARG A 1 272 ? 153.592 124.337 107.036 1.00 74.80  ? 272 ARG A CZ  1 
ATOM   1630 N  NH1 . ARG A 1 272 ? 154.296 125.260 106.402 1.00 74.80  ? 272 ARG A NH1 1 
ATOM   1631 N  NH2 . ARG A 1 272 ? 154.091 123.111 107.162 1.00 74.80  ? 272 ARG A NH2 1 
ATOM   1632 N  N   . TYR A 1 273 ? 152.739 131.109 107.687 1.00 77.45  ? 273 TYR A N   1 
ATOM   1633 C  CA  . TYR A 1 273 ? 153.545 131.855 106.721 1.00 77.45  ? 273 TYR A CA  1 
ATOM   1634 C  C   . TYR A 1 273 ? 153.578 133.318 107.139 1.00 77.45  ? 273 TYR A C   1 
ATOM   1635 O  O   . TYR A 1 273 ? 152.884 134.160 106.553 1.00 77.45  ? 273 TYR A O   1 
ATOM   1636 C  CB  . TYR A 1 273 ? 152.995 131.697 105.303 1.00 77.45  ? 273 TYR A CB  1 
ATOM   1637 C  CG  . TYR A 1 273 ? 152.833 130.260 104.866 1.00 77.45  ? 273 TYR A CG  1 
ATOM   1638 C  CD1 . TYR A 1 273 ? 153.882 129.571 104.275 1.00 77.45  ? 273 TYR A CD1 1 
ATOM   1639 C  CD2 . TYR A 1 273 ? 151.630 129.592 105.047 1.00 77.45  ? 273 TYR A CD2 1 
ATOM   1640 C  CE1 . TYR A 1 273 ? 153.738 128.258 103.874 1.00 77.45  ? 273 TYR A CE1 1 
ATOM   1641 C  CE2 . TYR A 1 273 ? 151.477 128.278 104.650 1.00 77.45  ? 273 TYR A CE2 1 
ATOM   1642 C  CZ  . TYR A 1 273 ? 152.534 127.617 104.064 1.00 77.45  ? 273 TYR A CZ  1 
ATOM   1643 O  OH  . TYR A 1 273 ? 152.385 126.308 103.668 1.00 77.45  ? 273 TYR A OH  1 
ATOM   1644 N  N   . PRO A 1 274 ? 154.371 133.656 108.158 1.00 85.24  ? 274 PRO A N   1 
ATOM   1645 C  CA  . PRO A 1 274 ? 154.436 135.060 108.596 1.00 85.24  ? 274 PRO A CA  1 
ATOM   1646 C  C   . PRO A 1 274 ? 154.968 136.004 107.532 1.00 85.24  ? 274 PRO A C   1 
ATOM   1647 O  O   . PRO A 1 274 ? 154.574 137.176 107.506 1.00 85.24  ? 274 PRO A O   1 
ATOM   1648 C  CB  . PRO A 1 274 ? 155.364 135.010 109.821 1.00 85.24  ? 274 PRO A CB  1 
ATOM   1649 C  CG  . PRO A 1 274 ? 155.517 133.555 110.164 1.00 85.24  ? 274 PRO A CG  1 
ATOM   1650 C  CD  . PRO A 1 274 ? 155.304 132.796 108.901 1.00 85.24  ? 274 PRO A CD  1 
ATOM   1651 N  N   . ASP A 1 275 ? 155.858 135.531 106.658 1.00 87.88  ? 275 ASP A N   1 
ATOM   1652 C  CA  . ASP A 1 275 ? 156.441 136.408 105.647 1.00 87.88  ? 275 ASP A CA  1 
ATOM   1653 C  C   . ASP A 1 275 ? 155.391 136.897 104.657 1.00 87.88  ? 275 ASP A C   1 
ATOM   1654 O  O   . ASP A 1 275 ? 155.424 138.058 104.234 1.00 87.88  ? 275 ASP A O   1 
ATOM   1655 C  CB  . ASP A 1 275 ? 157.574 135.687 104.919 1.00 87.88  ? 275 ASP A CB  1 
ATOM   1656 C  CG  . ASP A 1 275 ? 158.528 134.990 105.870 1.00 87.88  ? 275 ASP A CG  1 
ATOM   1657 O  OD1 . ASP A 1 275 ? 158.632 135.427 107.036 1.00 87.88  ? 275 ASP A OD1 1 
ATOM   1658 O  OD2 . ASP A 1 275 ? 159.175 134.008 105.452 1.00 87.88  ? 275 ASP A OD2 1 
ATOM   1659 N  N   . CYS A 1 276 ? 154.457 136.031 104.275 1.00 88.00  ? 276 CYS A N   1 
ATOM   1660 C  CA  . CYS A 1 276 ? 153.432 136.415 103.314 1.00 88.00  ? 276 CYS A CA  1 
ATOM   1661 C  C   . CYS A 1 276 ? 152.449 137.400 103.934 1.00 88.00  ? 276 CYS A C   1 
ATOM   1662 O  O   . CYS A 1 276 ? 151.922 137.175 105.026 1.00 88.00  ? 276 CYS A O   1 
ATOM   1663 C  CB  . CYS A 1 276 ? 152.685 135.180 102.813 1.00 88.00  ? 276 CYS A CB  1 
ATOM   1664 N  N   . ARG A 1 277 ? 152.197 138.500 103.218 1.00 85.73  ? 277 ARG A N   1 
ATOM   1665 C  CA  . ARG A 1 277 ? 151.237 139.514 103.641 1.00 85.73  ? 277 ARG A CA  1 
ATOM   1666 C  C   . ARG A 1 277 ? 150.206 139.802 102.555 1.00 85.73  ? 277 ARG A C   1 
ATOM   1667 O  O   . ARG A 1 277 ? 149.614 140.886 102.542 1.00 85.73  ? 277 ARG A O   1 
ATOM   1668 C  CB  . ARG A 1 277 ? 151.953 140.808 104.039 1.00 85.73  ? 277 ARG A CB  1 
ATOM   1669 C  CG  . ARG A 1 277 ? 152.787 140.733 105.315 1.00 85.73  ? 277 ARG A CG  1 
ATOM   1670 C  CD  . ARG A 1 277 ? 151.925 140.894 106.567 1.00 85.73  ? 277 ARG A CD  1 
ATOM   1671 N  NE  . ARG A 1 277 ? 151.204 139.680 106.929 1.00 85.73  ? 277 ARG A NE  1 
ATOM   1672 C  CZ  . ARG A 1 277 ? 151.734 138.670 107.606 1.00 85.73  ? 277 ARG A CZ  1 
ATOM   1673 N  NH1 . ARG A 1 277 ? 152.985 138.706 108.032 1.00 85.73  ? 277 ARG A NH1 1 
ATOM   1674 N  NH2 . ARG A 1 277 ? 150.988 137.600 107.866 1.00 85.73  ? 277 ARG A NH2 1 
ATOM   1675 N  N   . CYS A 1 278 ? 149.980 138.854 101.643 1.00 83.76  ? 278 CYS A N   1 
ATOM   1676 C  CA  . CYS A 1 278 ? 149.089 139.105 100.515 1.00 83.76  ? 278 CYS A CA  1 
ATOM   1677 C  C   . CYS A 1 278 ? 147.630 139.169 100.952 1.00 83.76  ? 278 CYS A C   1 
ATOM   1678 O  O   . CYS A 1 278 ? 146.856 139.978 100.427 1.00 83.76  ? 278 CYS A O   1 
ATOM   1679 C  CB  . CYS A 1 278 ? 149.281 138.028 99.449  1.00 83.76  ? 278 CYS A CB  1 
ATOM   1680 S  SG  . CYS A 1 278 ? 150.918 138.016 98.682  1.00 83.76  ? 278 CYS A SG  1 
ATOM   1681 N  N   . LEU A 1 279 ? 147.234 138.327 101.903 1.00 76.63  ? 279 LEU A N   1 
ATOM   1682 C  CA  . LEU A 1 279 ? 145.828 138.224 102.272 1.00 76.63  ? 279 LEU A CA  1 
ATOM   1683 C  C   . LEU A 1 279 ? 145.363 139.466 103.021 1.00 76.63  ? 279 LEU A C   1 
ATOM   1684 O  O   . LEU A 1 279 ? 145.982 139.883 104.005 1.00 76.63  ? 279 LEU A O   1 
ATOM   1685 C  CB  . LEU A 1 279 ? 145.588 136.978 103.122 1.00 76.63  ? 279 LEU A CB  1 
ATOM   1686 C  CG  . LEU A 1 279 ? 145.342 135.660 102.384 1.00 76.63  ? 279 LEU A CG  1 
ATOM   1687 C  CD1 . LEU A 1 279 ? 146.598 135.149 101.700 1.00 76.63  ? 279 LEU A CD1 1 
ATOM   1688 C  CD2 . LEU A 1 279 ? 144.803 134.624 103.355 1.00 76.63  ? 279 LEU A CD2 1 
ATOM   1689 N  N   . ASN A 1 280 ? 144.261 140.043 102.553 1.00 72.28  ? 280 ASN A N   1 
ATOM   1690 C  CA  . ASN A 1 280 ? 143.618 141.185 103.192 1.00 72.28  ? 280 ASN A CA  1 
ATOM   1691 C  C   . ASN A 1 280 ? 142.202 141.295 102.638 1.00 72.28  ? 280 ASN A C   1 
ATOM   1692 O  O   . ASN A 1 280 ? 141.779 140.492 101.802 1.00 72.28  ? 280 ASN A O   1 
ATOM   1693 C  CB  . ASN A 1 280 ? 144.463 142.461 103.022 1.00 72.28  ? 280 ASN A CB  1 
ATOM   1694 C  CG  . ASN A 1 280 ? 144.337 143.114 101.637 1.00 72.28  ? 280 ASN A CG  1 
ATOM   1695 O  OD1 . ASN A 1 280 ? 143.302 143.063 100.975 1.00 72.28  ? 280 ASN A OD1 1 
ATOM   1696 N  ND2 . ASN A 1 280 ? 145.421 143.744 101.203 1.00 72.28  ? 280 ASN A ND2 1 
ATOM   1697 N  N   . PHE A 1 281 ? 141.467 142.300 103.115 1.00 66.59  ? 281 PHE A N   1 
ATOM   1698 C  CA  . PHE A 1 281 ? 140.088 142.482 102.671 1.00 66.59  ? 281 PHE A CA  1 
ATOM   1699 C  C   . PHE A 1 281 ? 140.027 142.786 101.179 1.00 66.59  ? 281 PHE A C   1 
ATOM   1700 O  O   . PHE A 1 281 ? 139.216 142.204 100.446 1.00 66.59  ? 281 PHE A O   1 
ATOM   1701 C  CB  . PHE A 1 281 ? 139.426 143.600 103.476 1.00 66.59  ? 281 PHE A CB  1 
ATOM   1702 C  CG  . PHE A 1 281 ? 137.942 143.705 103.264 1.00 66.59  ? 281 PHE A CG  1 
ATOM   1703 C  CD1 . PHE A 1 281 ? 137.427 144.464 102.225 1.00 66.59  ? 281 PHE A CD1 1 
ATOM   1704 C  CD2 . PHE A 1 281 ? 137.062 143.050 104.108 1.00 66.59  ? 281 PHE A CD2 1 
ATOM   1705 C  CE1 . PHE A 1 281 ? 136.067 144.562 102.030 1.00 66.59  ? 281 PHE A CE1 1 
ATOM   1706 C  CE2 . PHE A 1 281 ? 135.699 143.147 103.918 1.00 66.59  ? 281 PHE A CE2 1 
ATOM   1707 C  CZ  . PHE A 1 281 ? 135.201 143.903 102.876 1.00 66.59  ? 281 PHE A CZ  1 
ATOM   1708 N  N   . GLY A 1 282 ? 140.886 143.694 100.711 1.00 67.53  ? 282 GLY A N   1 
ATOM   1709 C  CA  . GLY A 1 282 ? 140.816 144.115 99.321  1.00 67.53  ? 282 GLY A CA  1 
ATOM   1710 C  C   . GLY A 1 282 ? 141.117 142.990 98.352  1.00 67.53  ? 282 GLY A C   1 
ATOM   1711 O  O   . GLY A 1 282 ? 140.387 142.780 97.381  1.00 67.53  ? 282 GLY A O   1 
ATOM   1712 N  N   . SER A 1 283 ? 142.188 142.237 98.613  1.00 67.40  ? 283 SER A N   1 
ATOM   1713 C  CA  . SER A 1 283 ? 142.549 141.141 97.720  1.00 67.40  ? 283 SER A CA  1 
ATOM   1714 C  C   . SER A 1 283 ? 141.465 140.071 97.697  1.00 67.40  ? 283 SER A C   1 
ATOM   1715 O  O   . SER A 1 283 ? 141.061 139.604 96.620  1.00 67.40  ? 283 SER A O   1 
ATOM   1716 C  CB  . SER A 1 283 ? 143.887 140.536 98.144  1.00 67.40  ? 283 SER A CB  1 
ATOM   1717 O  OG  . SER A 1 283 ? 144.968 141.369 97.764  1.00 67.40  ? 283 SER A OG  1 
ATOM   1718 N  N   . TRP A 1 284 ? 140.974 139.684 98.878  1.00 62.19  ? 284 TRP A N   1 
ATOM   1719 C  CA  . TRP A 1 284 ? 139.947 138.653 98.960  1.00 62.19  ? 284 TRP A CA  1 
ATOM   1720 C  C   . TRP A 1 284 ? 138.696 139.076 98.210  1.00 62.19  ? 284 TRP A C   1 
ATOM   1721 O  O   . TRP A 1 284 ? 138.116 138.289 97.454  1.00 62.19  ? 284 TRP A O   1 
ATOM   1722 C  CB  . TRP A 1 284 ? 139.620 138.348 100.422 1.00 62.19  ? 284 TRP A CB  1 
ATOM   1723 C  CG  . TRP A 1 284 ? 138.853 137.074 100.607 1.00 62.19  ? 284 TRP A CG  1 
ATOM   1724 C  CD1 . TRP A 1 284 ? 137.498 136.934 100.647 1.00 62.19  ? 284 TRP A CD1 1 
ATOM   1725 C  CD2 . TRP A 1 284 ? 139.396 135.761 100.785 1.00 62.19  ? 284 TRP A CD2 1 
ATOM   1726 N  NE1 . TRP A 1 284 ? 137.162 135.616 100.833 1.00 62.19  ? 284 TRP A NE1 1 
ATOM   1727 C  CE2 . TRP A 1 284 ? 138.311 134.876 100.924 1.00 62.19  ? 284 TRP A CE2 1 
ATOM   1728 C  CE3 . TRP A 1 284 ? 140.694 135.250 100.845 1.00 62.19  ? 284 TRP A CE3 1 
ATOM   1729 C  CZ2 . TRP A 1 284 ? 138.483 133.509 101.114 1.00 62.19  ? 284 TRP A CZ2 1 
ATOM   1730 C  CZ3 . TRP A 1 284 ? 140.864 133.893 101.030 1.00 62.19  ? 284 TRP A CZ3 1 
ATOM   1731 C  CH2 . TRP A 1 284 ? 139.765 133.037 101.164 1.00 62.19  ? 284 TRP A CH2 1 
ATOM   1732 N  N   . PHE A 1 285 ? 138.272 140.328 98.394  1.00 63.47  ? 285 PHE A N   1 
ATOM   1733 C  CA  . PHE A 1 285 ? 137.118 140.815 97.650  1.00 63.47  ? 285 PHE A CA  1 
ATOM   1734 C  C   . PHE A 1 285 ? 137.384 140.795 96.152  1.00 63.47  ? 285 PHE A C   1 
ATOM   1735 O  O   . PHE A 1 285 ? 136.518 140.386 95.370  1.00 63.47  ? 285 PHE A O   1 
ATOM   1736 C  CB  . PHE A 1 285 ? 136.743 142.221 98.110  1.00 63.47  ? 285 PHE A CB  1 
ATOM   1737 C  CG  . PHE A 1 285 ? 135.273 142.503 98.043  1.00 63.47  ? 285 PHE A CG  1 
ATOM   1738 C  CD1 . PHE A 1 285 ? 134.421 142.045 99.034  1.00 63.47  ? 285 PHE A CD1 1 
ATOM   1739 C  CD2 . PHE A 1 285 ? 134.738 143.219 96.986  1.00 63.47  ? 285 PHE A CD2 1 
ATOM   1740 C  CE1 . PHE A 1 285 ? 133.066 142.300 98.975  1.00 63.47  ? 285 PHE A CE1 1 
ATOM   1741 C  CE2 . PHE A 1 285 ? 133.384 143.478 96.922  1.00 63.47  ? 285 PHE A CE2 1 
ATOM   1742 C  CZ  . PHE A 1 285 ? 132.547 143.018 97.918  1.00 63.47  ? 285 PHE A CZ  1 
ATOM   1743 N  N   . THR A 1 286 ? 138.589 141.198 95.734  1.00 65.67  ? 286 THR A N   1 
ATOM   1744 C  CA  . THR A 1 286 ? 138.879 141.283 94.307  1.00 65.67  ? 286 THR A CA  1 
ATOM   1745 C  C   . THR A 1 286 ? 138.795 139.920 93.634  1.00 65.67  ? 286 THR A C   1 
ATOM   1746 O  O   . THR A 1 286 ? 138.249 139.808 92.530  1.00 65.67  ? 286 THR A O   1 
ATOM   1747 C  CB  . THR A 1 286 ? 140.254 141.904 94.063  1.00 65.67  ? 286 THR A CB  1 
ATOM   1748 O  OG1 . THR A 1 286 ? 141.223 141.282 94.912  1.00 65.67  ? 286 THR A OG1 1 
ATOM   1749 C  CG2 . THR A 1 286 ? 140.224 143.403 94.325  1.00 65.67  ? 286 THR A CG2 1 
ATOM   1750 N  N   . PHE A 1 287 ? 139.328 138.869 94.261  1.00 65.27  ? 287 PHE A N   1 
ATOM   1751 C  CA  . PHE A 1 287 ? 139.242 137.575 93.584  1.00 65.27  ? 287 PHE A CA  1 
ATOM   1752 C  C   . PHE A 1 287 ? 138.056 136.733 94.039  1.00 65.27  ? 287 PHE A C   1 
ATOM   1753 O  O   . PHE A 1 287 ? 137.926 135.591 93.589  1.00 65.27  ? 287 PHE A O   1 
ATOM   1754 C  CB  . PHE A 1 287 ? 140.530 136.737 93.711  1.00 65.27  ? 287 PHE A CB  1 
ATOM   1755 C  CG  . PHE A 1 287 ? 140.830 136.229 95.093  1.00 65.27  ? 287 PHE A CG  1 
ATOM   1756 C  CD1 . PHE A 1 287 ? 141.612 136.950 95.966  1.00 65.27  ? 287 PHE A CD1 1 
ATOM   1757 C  CD2 . PHE A 1 287 ? 140.351 134.993 95.501  1.00 65.27  ? 287 PHE A CD2 1 
ATOM   1758 C  CE1 . PHE A 1 287 ? 141.898 136.466 97.226  1.00 65.27  ? 287 PHE A CE1 1 
ATOM   1759 C  CE2 . PHE A 1 287 ? 140.627 134.506 96.759  1.00 65.27  ? 287 PHE A CE2 1 
ATOM   1760 C  CZ  . PHE A 1 287 ? 141.403 135.244 97.622  1.00 65.27  ? 287 PHE A CZ  1 
ATOM   1761 N  N   . SER A 1 288 ? 137.192 137.250 94.912  1.00 58.67  ? 288 SER A N   1 
ATOM   1762 C  CA  . SER A 1 288 ? 136.000 136.508 95.303  1.00 58.67  ? 288 SER A CA  1 
ATOM   1763 C  C   . SER A 1 288 ? 134.716 137.054 94.694  1.00 58.67  ? 288 SER A C   1 
ATOM   1764 O  O   . SER A 1 288 ? 133.794 136.279 94.425  1.00 58.67  ? 288 SER A O   1 
ATOM   1765 C  CB  . SER A 1 288 ? 135.866 136.494 96.829  1.00 58.67  ? 288 SER A CB  1 
ATOM   1766 O  OG  . SER A 1 288 ? 136.935 135.782 97.424  1.00 58.67  ? 288 SER A OG  1 
ATOM   1767 N  N   . PHE A 1 289 ? 134.627 138.366 94.470  1.00 58.68  ? 289 PHE A N   1 
ATOM   1768 C  CA  . PHE A 1 289 ? 133.381 138.952 93.980  1.00 58.68  ? 289 PHE A CA  1 
ATOM   1769 C  C   . PHE A 1 289 ? 132.949 138.417 92.619  1.00 58.68  ? 289 PHE A C   1 
ATOM   1770 O  O   . PHE A 1 289 ? 131.760 138.088 92.466  1.00 58.68  ? 289 PHE A O   1 
ATOM   1771 C  CB  . PHE A 1 289 ? 133.506 140.478 93.969  1.00 58.68  ? 289 PHE A CB  1 
ATOM   1772 C  CG  . PHE A 1 289 ? 132.200 141.191 94.155  1.00 58.68  ? 289 PHE A CG  1 
ATOM   1773 C  CD1 . PHE A 1 289 ? 131.477 141.039 95.325  1.00 58.68  ? 289 PHE A CD1 1 
ATOM   1774 C  CD2 . PHE A 1 289 ? 131.703 142.026 93.170  1.00 58.68  ? 289 PHE A CD2 1 
ATOM   1775 C  CE1 . PHE A 1 289 ? 130.277 141.695 95.505  1.00 58.68  ? 289 PHE A CE1 1 
ATOM   1776 C  CE2 . PHE A 1 289 ? 130.504 142.688 93.346  1.00 58.68  ? 289 PHE A CE2 1 
ATOM   1777 C  CZ  . PHE A 1 289 ? 129.790 142.521 94.514  1.00 58.68  ? 289 PHE A CZ  1 
ATOM   1778 N  N   . PRO A 1 290 ? 133.814 138.316 91.600  1.00 55.89  ? 290 PRO A N   1 
ATOM   1779 C  CA  . PRO A 1 290 ? 133.330 137.786 90.312  1.00 55.89  ? 290 PRO A CA  1 
ATOM   1780 C  C   . PRO A 1 290 ? 132.810 136.363 90.407  1.00 55.89  ? 290 PRO A C   1 
ATOM   1781 O  O   . PRO A 1 290 ? 131.720 136.065 89.896  1.00 55.89  ? 290 PRO A O   1 
ATOM   1782 C  CB  . PRO A 1 290 ? 134.565 137.880 89.403  1.00 55.89  ? 290 PRO A CB  1 
ATOM   1783 C  CG  . PRO A 1 290 ? 135.477 138.841 90.070  1.00 55.89  ? 290 PRO A CG  1 
ATOM   1784 C  CD  . PRO A 1 290 ? 135.238 138.692 91.530  1.00 55.89  ? 290 PRO A CD  1 
ATOM   1785 N  N   . ALA A 1 291 ? 133.564 135.476 91.060  1.00 51.41  ? 291 ALA A N   1 
ATOM   1786 C  CA  . ALA A 1 291 ? 133.119 134.095 91.209  1.00 51.41  ? 291 ALA A CA  1 
ATOM   1787 C  C   . ALA A 1 291 ? 131.833 134.018 92.015  1.00 51.41  ? 291 ALA A C   1 
ATOM   1788 O  O   . ALA A 1 291 ? 130.931 133.243 91.679  1.00 51.41  ? 291 ALA A O   1 
ATOM   1789 C  CB  . ALA A 1 291 ? 134.215 133.256 91.863  1.00 51.41  ? 291 ALA A CB  1 
ATOM   1790 N  N   . ALA A 1 292 ? 131.728 134.815 93.081  1.00 47.08  ? 292 ALA A N   1 
ATOM   1791 C  CA  . ALA A 1 292 ? 130.517 134.803 93.894  1.00 47.08  ? 292 ALA A CA  1 
ATOM   1792 C  C   . ALA A 1 292 ? 129.305 135.254 93.091  1.00 47.08  ? 292 ALA A C   1 
ATOM   1793 O  O   . ALA A 1 292 ? 128.240 134.633 93.167  1.00 47.08  ? 292 ALA A O   1 
ATOM   1794 C  CB  . ALA A 1 292 ? 130.700 135.685 95.127  1.00 47.08  ? 292 ALA A CB  1 
ATOM   1795 N  N   . LEU A 1 293 ? 129.446 136.328 92.309  1.00 50.47  ? 293 LEU A N   1 
ATOM   1796 C  CA  . LEU A 1 293 ? 128.324 136.800 91.501  1.00 50.47  ? 293 LEU A CA  1 
ATOM   1797 C  C   . LEU A 1 293 ? 127.920 135.770 90.455  1.00 50.47  ? 293 LEU A C   1 
ATOM   1798 O  O   . LEU A 1 293 ? 126.725 135.515 90.251  1.00 50.47  ? 293 LEU A O   1 
ATOM   1799 C  CB  . LEU A 1 293 ? 128.674 138.124 90.826  1.00 50.47  ? 293 LEU A CB  1 
ATOM   1800 C  CG  . LEU A 1 293 ? 128.893 139.348 91.713  1.00 50.47  ? 293 LEU A CG  1 
ATOM   1801 C  CD1 . LEU A 1 293 ? 129.365 140.514 90.866  1.00 50.47  ? 293 LEU A CD1 1 
ATOM   1802 C  CD2 . LEU A 1 293 ? 127.619 139.707 92.455  1.00 50.47  ? 293 LEU A CD2 1 
ATOM   1803 N  N   . ILE A 1 294 ? 128.901 135.167 89.778  1.00 49.93  ? 294 ILE A N   1 
ATOM   1804 C  CA  . ILE A 1 294 ? 128.579 134.174 88.758  1.00 49.93  ? 294 ILE A CA  1 
ATOM   1805 C  C   . ILE A 1 294 ? 127.871 132.979 89.382  1.00 49.93  ? 294 ILE A C   1 
ATOM   1806 O  O   . ILE A 1 294 ? 126.860 132.492 88.857  1.00 49.93  ? 294 ILE A O   1 
ATOM   1807 C  CB  . ILE A 1 294 ? 129.848 133.750 87.998  1.00 49.93  ? 294 ILE A CB  1 
ATOM   1808 C  CG1 . ILE A 1 294 ? 130.446 134.943 87.253  1.00 49.93  ? 294 ILE A CG1 1 
ATOM   1809 C  CG2 . ILE A 1 294 ? 129.537 132.627 87.029  1.00 49.93  ? 294 ILE A CG2 1 
ATOM   1810 C  CD1 . ILE A 1 294 ? 131.669 134.598 86.434  1.00 49.93  ? 294 ILE A CD1 1 
ATOM   1811 N  N   . ILE A 1 295 ? 128.381 132.496 90.518  1.00 45.06  ? 295 ILE A N   1 
ATOM   1812 C  CA  . ILE A 1 295 ? 127.772 131.347 91.177  1.00 45.06  ? 295 ILE A CA  1 
ATOM   1813 C  C   . ILE A 1 295 ? 126.360 131.685 91.635  1.00 45.06  ? 295 ILE A C   1 
ATOM   1814 O  O   . ILE A 1 295 ? 125.441 130.872 91.500  1.00 45.06  ? 295 ILE A O   1 
ATOM   1815 C  CB  . ILE A 1 295 ? 128.648 130.874 92.350  1.00 45.06  ? 295 ILE A CB  1 
ATOM   1816 C  CG1 . ILE A 1 295 ? 129.941 130.251 91.836  1.00 45.06  ? 295 ILE A CG1 1 
ATOM   1817 C  CG2 . ILE A 1 295 ? 127.916 129.842 93.162  1.00 45.06  ? 295 ILE A CG2 1 
ATOM   1818 C  CD1 . ILE A 1 295 ? 130.940 129.949 92.927  1.00 45.06  ? 295 ILE A CD1 1 
ATOM   1819 N  N   . LEU A 1 296 ? 126.163 132.886 92.181  1.00 48.19  ? 296 LEU A N   1 
ATOM   1820 C  CA  . LEU A 1 296 ? 124.838 133.277 92.651  1.00 48.19  ? 296 LEU A CA  1 
ATOM   1821 C  C   . LEU A 1 296 ? 123.841 133.330 91.501  1.00 48.19  ? 296 LEU A C   1 
ATOM   1822 O  O   . LEU A 1 296 ? 122.721 132.818 91.614  1.00 48.19  ? 296 LEU A O   1 
ATOM   1823 C  CB  . LEU A 1 296 ? 124.917 134.627 93.365  1.00 48.19  ? 296 LEU A CB  1 
ATOM   1824 C  CG  . LEU A 1 296 ? 123.690 135.091 94.153  1.00 48.19  ? 296 LEU A CG  1 
ATOM   1825 C  CD1 . LEU A 1 296 ? 124.131 135.819 95.407  1.00 48.19  ? 296 LEU A CD1 1 
ATOM   1826 C  CD2 . LEU A 1 296 ? 122.802 135.989 93.307  1.00 48.19  ? 296 LEU A CD2 1 
ATOM   1827 N  N   . LEU A 1 297 ? 124.231 133.942 90.380  1.00 50.58  ? 297 LEU A N   1 
ATOM   1828 C  CA  . LEU A 1 297 ? 123.317 134.033 89.244  1.00 50.58  ? 297 LEU A CA  1 
ATOM   1829 C  C   . LEU A 1 297 ? 122.996 132.655 88.676  1.00 50.58  ? 297 LEU A C   1 
ATOM   1830 O  O   . LEU A 1 297 ? 121.828 132.347 88.391  1.00 50.58  ? 297 LEU A O   1 
ATOM   1831 C  CB  . LEU A 1 297 ? 123.906 134.939 88.164  1.00 50.58  ? 297 LEU A CB  1 
ATOM   1832 C  CG  . LEU A 1 297 ? 123.518 136.422 88.211  1.00 50.58  ? 297 LEU A CG  1 
ATOM   1833 C  CD1 . LEU A 1 297 ? 122.020 136.588 88.011  1.00 50.58  ? 297 LEU A CD1 1 
ATOM   1834 C  CD2 . LEU A 1 297 ? 123.963 137.082 89.507  1.00 50.58  ? 297 LEU A CD2 1 
ATOM   1835 N  N   . LEU A 1 298 ? 124.012 131.804 88.515  1.00 50.86  ? 298 LEU A N   1 
ATOM   1836 C  CA  . LEU A 1 298 ? 123.768 130.477 87.963  1.00 50.86  ? 298 LEU A CA  1 
ATOM   1837 C  C   . LEU A 1 298 ? 122.927 129.627 88.910  1.00 50.86  ? 298 LEU A C   1 
ATOM   1838 O  O   . LEU A 1 298 ? 122.073 128.854 88.463  1.00 50.86  ? 298 LEU A O   1 
ATOM   1839 C  CB  . LEU A 1 298 ? 125.094 129.792 87.645  1.00 50.86  ? 298 LEU A CB  1 
ATOM   1840 C  CG  . LEU A 1 298 ? 125.932 130.462 86.553  1.00 50.86  ? 298 LEU A CG  1 
ATOM   1841 C  CD1 . LEU A 1 298 ? 127.031 129.531 86.068  1.00 50.86  ? 298 LEU A CD1 1 
ATOM   1842 C  CD2 . LEU A 1 298 ? 125.057 130.915 85.394  1.00 50.86  ? 298 LEU A CD2 1 
ATOM   1843 N  N   . SER A 1 299 ? 123.145 129.761 90.220  1.00 51.96  ? 299 SER A N   1 
ATOM   1844 C  CA  . SER A 1 299 ? 122.336 129.030 91.187  1.00 51.96  ? 299 SER A CA  1 
ATOM   1845 C  C   . SER A 1 299 ? 120.894 129.518 91.181  1.00 51.96  ? 299 SER A C   1 
ATOM   1846 O  O   . SER A 1 299 ? 119.965 128.715 91.316  1.00 51.96  ? 299 SER A O   1 
ATOM   1847 C  CB  . SER A 1 299 ? 122.941 129.159 92.583  1.00 51.96  ? 299 SER A CB  1 
ATOM   1848 O  OG  . SER A 1 299 ? 122.879 130.497 93.041  1.00 51.96  ? 299 SER A OG  1 
ATOM   1849 N  N   . TRP A 1 300 ? 120.686 130.829 91.034  1.00 53.67  ? 300 TRP A N   1 
ATOM   1850 C  CA  . TRP A 1 300 ? 119.326 131.340 90.906  1.00 53.67  ? 300 TRP A CA  1 
ATOM   1851 C  C   . TRP A 1 300 ? 118.640 130.749 89.685  1.00 53.67  ? 300 TRP A C   1 
ATOM   1852 O  O   . TRP A 1 300 ? 117.477 130.332 89.755  1.00 53.67  ? 300 TRP A O   1 
ATOM   1853 C  CB  . TRP A 1 300 ? 119.334 132.863 90.799  1.00 53.67  ? 300 TRP A CB  1 
ATOM   1854 C  CG  . TRP A 1 300 ? 118.017 133.412 90.341  1.00 53.67  ? 300 TRP A CG  1 
ATOM   1855 C  CD1 . TRP A 1 300 ? 116.778 133.041 90.778  1.00 53.67  ? 300 TRP A CD1 1 
ATOM   1856 C  CD2 . TRP A 1 300 ? 117.802 134.367 89.296  1.00 53.67  ? 300 TRP A CD2 1 
ATOM   1857 N  NE1 . TRP A 1 300 ? 115.809 133.739 90.102  1.00 53.67  ? 300 TRP A NE1 1 
ATOM   1858 C  CE2 . TRP A 1 300 ? 116.411 134.557 89.183  1.00 53.67  ? 300 TRP A CE2 1 
ATOM   1859 C  CE3 . TRP A 1 300 ? 118.651 135.094 88.458  1.00 53.67  ? 300 TRP A CE3 1 
ATOM   1860 C  CZ2 . TRP A 1 300 ? 115.850 135.442 88.267  1.00 53.67  ? 300 TRP A CZ2 1 
ATOM   1861 C  CZ3 . TRP A 1 300 ? 118.092 135.974 87.549  1.00 53.67  ? 300 TRP A CZ3 1 
ATOM   1862 C  CH2 . TRP A 1 300 ? 116.705 136.138 87.460  1.00 53.67  ? 300 TRP A CH2 1 
ATOM   1863 N  N   . ILE A 1 301 ? 119.346 130.714 88.553  1.00 54.63  ? 301 ILE A N   1 
ATOM   1864 C  CA  . ILE A 1 301 ? 118.762 130.151 87.339  1.00 54.63  ? 301 ILE A CA  1 
ATOM   1865 C  C   . ILE A 1 301 ? 118.423 128.680 87.543  1.00 54.63  ? 301 ILE A C   1 
ATOM   1866 O  O   . ILE A 1 301 ? 117.337 128.218 87.171  1.00 54.63  ? 301 ILE A O   1 
ATOM   1867 C  CB  . ILE A 1 301 ? 119.711 130.360 86.145  1.00 54.63  ? 301 ILE A CB  1 
ATOM   1868 C  CG1 . ILE A 1 301 ? 119.712 131.829 85.724  1.00 54.63  ? 301 ILE A CG1 1 
ATOM   1869 C  CG2 . ILE A 1 301 ? 119.314 129.467 84.983  1.00 54.63  ? 301 ILE A CG2 1 
ATOM   1870 C  CD1 . ILE A 1 301 ? 120.567 132.116 84.515  1.00 54.63  ? 301 ILE A CD1 1 
ATOM   1871 N  N   . TRP A 1 302 ? 119.341 127.927 88.153  1.00 55.50  ? 302 TRP A N   1 
ATOM   1872 C  CA  . TRP A 1 302 ? 119.109 126.506 88.392  1.00 55.50  ? 302 TRP A CA  1 
ATOM   1873 C  C   . TRP A 1 302 ? 117.900 126.288 89.293  1.00 55.50  ? 302 TRP A C   1 
ATOM   1874 O  O   . TRP A 1 302 ? 117.054 125.428 89.020  1.00 55.50  ? 302 TRP A O   1 
ATOM   1875 C  CB  . TRP A 1 302 ? 120.362 125.879 89.003  1.00 55.50  ? 302 TRP A CB  1 
ATOM   1876 C  CG  . TRP A 1 302 ? 120.146 124.527 89.603  1.00 55.50  ? 302 TRP A CG  1 
ATOM   1877 C  CD1 . TRP A 1 302 ? 120.180 124.205 90.927  1.00 55.50  ? 302 TRP A CD1 1 
ATOM   1878 C  CD2 . TRP A 1 302 ? 119.883 123.308 88.900  1.00 55.50  ? 302 TRP A CD2 1 
ATOM   1879 N  NE1 . TRP A 1 302 ? 119.946 122.863 91.094  1.00 55.50  ? 302 TRP A NE1 1 
ATOM   1880 C  CE2 . TRP A 1 302 ? 119.761 122.289 89.864  1.00 55.50  ? 302 TRP A CE2 1 
ATOM   1881 C  CE3 . TRP A 1 302 ? 119.735 122.979 87.550  1.00 55.50  ? 302 TRP A CE3 1 
ATOM   1882 C  CZ2 . TRP A 1 302 ? 119.497 120.966 89.522  1.00 55.50  ? 302 TRP A CZ2 1 
ATOM   1883 C  CZ3 . TRP A 1 302 ? 119.474 121.665 87.212  1.00 55.50  ? 302 TRP A CZ3 1 
ATOM   1884 C  CH2 . TRP A 1 302 ? 119.357 120.675 88.193  1.00 55.50  ? 302 TRP A CH2 1 
ATOM   1885 N  N   . LEU A 1 303 ? 117.797 127.067 90.372  1.00 56.14  ? 303 LEU A N   1 
ATOM   1886 C  CA  . LEU A 1 303 ? 116.684 126.905 91.301  1.00 56.14  ? 303 LEU A CA  1 
ATOM   1887 C  C   . LEU A 1 303 ? 115.356 127.276 90.655  1.00 56.14  ? 303 LEU A C   1 
ATOM   1888 O  O   . LEU A 1 303 ? 114.352 126.584 90.853  1.00 56.14  ? 303 LEU A O   1 
ATOM   1889 C  CB  . LEU A 1 303 ? 116.919 127.742 92.558  1.00 56.14  ? 303 LEU A CB  1 
ATOM   1890 C  CG  . LEU A 1 303 ? 118.043 127.276 93.483  1.00 56.14  ? 303 LEU A CG  1 
ATOM   1891 C  CD1 . LEU A 1 303 ? 118.090 128.132 94.734  1.00 56.14  ? 303 LEU A CD1 1 
ATOM   1892 C  CD2 . LEU A 1 303 ? 117.868 125.812 93.841  1.00 56.14  ? 303 LEU A CD2 1 
ATOM   1893 N  N   . GLN A 1 304 ? 115.325 128.362 89.878  1.00 65.96  ? 304 GLN A N   1 
ATOM   1894 C  CA  . GLN A 1 304 ? 114.069 128.761 89.253  1.00 65.96  ? 304 GLN A CA  1 
ATOM   1895 C  C   . GLN A 1 304 ? 113.674 127.806 88.135  1.00 65.96  ? 304 GLN A C   1 
ATOM   1896 O  O   . GLN A 1 304 ? 112.483 127.674 87.830  1.00 65.96  ? 304 GLN A O   1 
ATOM   1897 C  CB  . GLN A 1 304 ? 114.160 130.193 88.726  1.00 65.96  ? 304 GLN A CB  1 
ATOM   1898 C  CG  . GLN A 1 304 ? 114.876 130.338 87.398  1.00 65.96  ? 304 GLN A CG  1 
ATOM   1899 C  CD  . GLN A 1 304 ? 114.928 131.775 86.926  1.00 65.96  ? 304 GLN A CD  1 
ATOM   1900 O  OE1 . GLN A 1 304 ? 114.447 132.679 87.608  1.00 65.96  ? 304 GLN A OE1 1 
ATOM   1901 N  NE2 . GLN A 1 304 ? 115.506 131.993 85.751  1.00 65.96  ? 304 GLN A NE2 1 
ATOM   1902 N  N   . TRP A 1 305 ? 114.646 127.136 87.511  1.00 71.44  ? 305 TRP A N   1 
ATOM   1903 C  CA  . TRP A 1 305 ? 114.308 126.131 86.510  1.00 71.44  ? 305 TRP A CA  1 
ATOM   1904 C  C   . TRP A 1 305 ? 113.819 124.845 87.162  1.00 71.44  ? 305 TRP A C   1 
ATOM   1905 O  O   . TRP A 1 305 ? 112.934 124.168 86.627  1.00 71.44  ? 305 TRP A O   1 
ATOM   1906 C  CB  . TRP A 1 305 ? 115.513 125.843 85.619  1.00 71.44  ? 305 TRP A CB  1 
ATOM   1907 C  CG  . TRP A 1 305 ? 115.218 124.839 84.552  1.00 71.44  ? 305 TRP A CG  1 
ATOM   1908 C  CD1 . TRP A 1 305 ? 114.346 124.983 83.515  1.00 71.44  ? 305 TRP A CD1 1 
ATOM   1909 C  CD2 . TRP A 1 305 ? 115.772 123.524 84.431  1.00 71.44  ? 305 TRP A CD2 1 
ATOM   1910 N  NE1 . TRP A 1 305 ? 114.333 123.845 82.746  1.00 71.44  ? 305 TRP A NE1 1 
ATOM   1911 C  CE2 . TRP A 1 305 ? 115.199 122.934 83.288  1.00 71.44  ? 305 TRP A CE2 1 
ATOM   1912 C  CE3 . TRP A 1 305 ? 116.701 122.792 85.174  1.00 71.44  ? 305 TRP A CE3 1 
ATOM   1913 C  CZ2 . TRP A 1 305 ? 115.525 121.646 82.871  1.00 71.44  ? 305 TRP A CZ2 1 
ATOM   1914 C  CZ3 . TRP A 1 305 ? 117.023 121.513 84.758  1.00 71.44  ? 305 TRP A CZ3 1 
ATOM   1915 C  CH2 . TRP A 1 305 ? 116.437 120.954 83.618  1.00 71.44  ? 305 TRP A CH2 1 
ATOM   1916 N  N   . LEU A 1 306 ? 114.391 124.490 88.314  1.00 64.23  ? 306 LEU A N   1 
ATOM   1917 C  CA  . LEU A 1 306 ? 114.085 123.203 88.930  1.00 64.23  ? 306 LEU A CA  1 
ATOM   1918 C  C   . LEU A 1 306 ? 112.638 123.136 89.404  1.00 64.23  ? 306 LEU A C   1 
ATOM   1919 O  O   . LEU A 1 306 ? 111.916 122.184 89.087  1.00 64.23  ? 306 LEU A O   1 
ATOM   1920 C  CB  . LEU A 1 306 ? 115.044 122.948 90.093  1.00 64.23  ? 306 LEU A CB  1 
ATOM   1921 C  CG  . LEU A 1 306 ? 115.047 121.541 90.689  1.00 64.23  ? 306 LEU A CG  1 
ATOM   1922 C  CD1 . LEU A 1 306 ? 115.447 120.517 89.641  1.00 64.23  ? 306 LEU A CD1 1 
ATOM   1923 C  CD2 . LEU A 1 306 ? 115.976 121.476 91.886  1.00 64.23  ? 306 LEU A CD2 1 
ATOM   1924 N  N   . PHE A 1 307 ? 112.193 124.138 90.162  1.00 65.97  ? 307 PHE A N   1 
ATOM   1925 C  CA  . PHE A 1 307 ? 110.892 124.086 90.822  1.00 65.97  ? 307 PHE A CA  1 
ATOM   1926 C  C   . PHE A 1 307 ? 109.792 124.781 90.025  1.00 65.97  ? 307 PHE A C   1 
ATOM   1927 O  O   . PHE A 1 307 ? 108.807 124.145 89.639  1.00 65.97  ? 307 PHE A O   1 
ATOM   1928 C  CB  . PHE A 1 307 ? 111.002 124.694 92.226  1.00 65.97  ? 307 PHE A CB  1 
ATOM   1929 C  CG  . PHE A 1 307 ? 112.030 124.026 93.091  1.00 65.97  ? 307 PHE A CG  1 
ATOM   1930 C  CD1 . PHE A 1 307 ? 112.049 122.649 93.224  1.00 65.97  ? 307 PHE A CD1 1 
ATOM   1931 C  CD2 . PHE A 1 307 ? 112.979 124.773 93.769  1.00 65.97  ? 307 PHE A CD2 1 
ATOM   1932 C  CE1 . PHE A 1 307 ? 112.993 122.028 94.018  1.00 65.97  ? 307 PHE A CE1 1 
ATOM   1933 C  CE2 . PHE A 1 307 ? 113.925 124.157 94.563  1.00 65.97  ? 307 PHE A CE2 1 
ATOM   1934 C  CZ  . PHE A 1 307 ? 113.932 122.783 94.687  1.00 65.97  ? 307 PHE A CZ  1 
ATOM   1935 N  N   . LEU A 1 308 ? 109.939 126.083 89.772  1.00 70.09  ? 308 LEU A N   1 
ATOM   1936 C  CA  . LEU A 1 308 ? 108.868 126.819 89.106  1.00 70.09  ? 308 LEU A CA  1 
ATOM   1937 C  C   . LEU A 1 308 ? 108.802 126.492 87.620  1.00 70.09  ? 308 LEU A C   1 
ATOM   1938 O  O   . LEU A 1 308 ? 107.711 126.319 87.065  1.00 70.09  ? 308 LEU A O   1 
ATOM   1939 C  CB  . LEU A 1 308 ? 109.051 128.322 89.311  1.00 70.09  ? 308 LEU A CB  1 
ATOM   1940 C  CG  . LEU A 1 308 ? 109.079 128.834 90.750  1.00 70.09  ? 308 LEU A CG  1 
ATOM   1941 C  CD1 . LEU A 1 308 ? 109.886 130.120 90.839  1.00 70.09  ? 308 LEU A CD1 1 
ATOM   1942 C  CD2 . LEU A 1 308 ? 107.666 129.044 91.271  1.00 70.09  ? 308 LEU A CD2 1 
ATOM   1943 N  N   . GLY A 1 309 ? 109.946 126.401 86.965  1.00 79.06  ? 309 GLY A N   1 
ATOM   1944 C  CA  . GLY A 1 309 ? 109.987 126.259 85.521  1.00 79.06  ? 309 GLY A CA  1 
ATOM   1945 C  C   . GLY A 1 309 ? 110.541 127.533 84.909  1.00 79.06  ? 309 GLY A C   1 
ATOM   1946 O  O   . GLY A 1 309 ? 110.254 128.645 85.369  1.00 79.06  ? 309 GLY A O   1 
ATOM   1947 N  N   . PHE A 1 310 ? 111.344 127.373 83.863  1.00 88.89  ? 310 PHE A N   1 
ATOM   1948 C  CA  . PHE A 1 310 ? 112.051 128.501 83.277  1.00 88.89  ? 310 PHE A CA  1 
ATOM   1949 C  C   . PHE A 1 310 ? 111.112 129.386 82.465  1.00 88.89  ? 310 PHE A C   1 
ATOM   1950 O  O   . PHE A 1 310 ? 110.071 128.943 81.972  1.00 88.89  ? 310 PHE A O   1 
ATOM   1951 C  CB  . PHE A 1 310 ? 113.197 128.011 82.392  1.00 88.89  ? 310 PHE A CB  1 
ATOM   1952 C  CG  . PHE A 1 310 ? 114.316 129.001 82.252  1.00 88.89  ? 310 PHE A CG  1 
ATOM   1953 C  CD1 . PHE A 1 310 ? 115.226 129.184 83.278  1.00 88.89  ? 310 PHE A CD1 1 
ATOM   1954 C  CD2 . PHE A 1 310 ? 114.458 129.746 81.094  1.00 88.89  ? 310 PHE A CD2 1 
ATOM   1955 C  CE1 . PHE A 1 310 ? 116.256 130.094 83.153  1.00 88.89  ? 310 PHE A CE1 1 
ATOM   1956 C  CE2 . PHE A 1 310 ? 115.488 130.657 80.963  1.00 88.89  ? 310 PHE A CE2 1 
ATOM   1957 C  CZ  . PHE A 1 310 ? 116.388 130.831 81.993  1.00 88.89  ? 310 PHE A CZ  1 
ATOM   1958 N  N   . ASN A 1 311 ? 111.495 130.655 82.337  1.00 96.15  ? 311 ASN A N   1 
ATOM   1959 C  CA  . ASN A 1 311 ? 110.762 131.627 81.541  1.00 96.15  ? 311 ASN A CA  1 
ATOM   1960 C  C   . ASN A 1 311 ? 111.754 132.414 80.696  1.00 96.15  ? 311 ASN A C   1 
ATOM   1961 O  O   . ASN A 1 311 ? 112.928 132.546 81.047  1.00 96.15  ? 311 ASN A O   1 
ATOM   1962 C  CB  . ASN A 1 311 ? 109.935 132.572 82.422  1.00 96.15  ? 311 ASN A CB  1 
ATOM   1963 C  CG  . ASN A 1 311 ? 108.776 131.869 83.103  1.00 96.15  ? 311 ASN A CG  1 
ATOM   1964 O  OD1 . ASN A 1 311 ? 108.132 130.999 82.517  1.00 96.15  ? 311 ASN A OD1 1 
ATOM   1965 N  ND2 . ASN A 1 311 ? 108.505 132.245 84.347  1.00 96.15  ? 311 ASN A ND2 1 
ATOM   1966 N  N   . PHE A 1 312 ? 111.269 132.942 79.572  1.00 99.81  ? 312 PHE A N   1 
ATOM   1967 C  CA  . PHE A 1 312 ? 112.126 133.616 78.604  1.00 99.81  ? 312 PHE A CA  1 
ATOM   1968 C  C   . PHE A 1 312 ? 111.889 135.121 78.551  1.00 99.81  ? 312 PHE A C   1 
ATOM   1969 O  O   . PHE A 1 312 ? 112.825 135.898 78.757  1.00 99.81  ? 312 PHE A O   1 
ATOM   1970 C  CB  . PHE A 1 312 ? 111.927 133.001 77.211  1.00 99.81  ? 312 PHE A CB  1 
ATOM   1971 C  CG  . PHE A 1 312 ? 112.645 131.697 77.013  1.00 99.81  ? 312 PHE A CG  1 
ATOM   1972 C  CD1 . PHE A 1 312 ? 113.652 131.304 77.879  1.00 99.81  ? 312 PHE A CD1 1 
ATOM   1973 C  CD2 . PHE A 1 312 ? 112.314 130.863 75.957  1.00 99.81  ? 312 PHE A CD2 1 
ATOM   1974 C  CE1 . PHE A 1 312 ? 114.315 130.105 77.696  1.00 99.81  ? 312 PHE A CE1 1 
ATOM   1975 C  CE2 . PHE A 1 312 ? 112.973 129.662 75.769  1.00 99.81  ? 312 PHE A CE2 1 
ATOM   1976 C  CZ  . PHE A 1 312 ? 113.974 129.283 76.641  1.00 99.81  ? 312 PHE A CZ  1 
ATOM   1977 N  N   . LYS A 1 313 ? 110.660 135.559 78.284  1.00 102.47 ? 313 LYS A N   1 
ATOM   1978 C  CA  . LYS A 1 313 ? 110.413 136.980 78.065  1.00 102.47 ? 313 LYS A CA  1 
ATOM   1979 C  C   . LYS A 1 313 ? 109.315 137.514 78.976  1.00 102.47 ? 313 LYS A C   1 
ATOM   1980 O  O   . LYS A 1 313 ? 109.279 138.714 79.268  1.00 102.47 ? 313 LYS A O   1 
ATOM   1981 C  CB  . LYS A 1 313 ? 110.062 137.238 76.598  1.00 102.47 ? 313 LYS A CB  1 
ATOM   1982 C  CG  . LYS A 1 313 ? 111.280 137.351 75.694  1.00 102.47 ? 313 LYS A CG  1 
ATOM   1983 C  CD  . LYS A 1 313 ? 110.893 137.364 74.226  1.00 102.47 ? 313 LYS A CD  1 
ATOM   1984 C  CE  . LYS A 1 313 ? 112.126 137.376 73.336  1.00 102.47 ? 313 LYS A CE  1 
ATOM   1985 N  NZ  . LYS A 1 313 ? 111.775 137.290 71.892  1.00 102.47 ? 313 LYS A NZ  1 
ATOM   1986 N  N   . GLU A 1 314 ? 108.414 136.639 79.426  1.00 99.70  ? 314 GLU A N   1 
ATOM   1987 C  CA  . GLU A 1 314 ? 107.437 137.048 80.428  1.00 99.70  ? 314 GLU A CA  1 
ATOM   1988 C  C   . GLU A 1 314 ? 108.108 137.438 81.737  1.00 99.70  ? 314 GLU A C   1 
ATOM   1989 O  O   . GLU A 1 314 ? 107.518 138.179 82.531  1.00 99.70  ? 314 GLU A O   1 
ATOM   1990 C  CB  . GLU A 1 314 ? 106.421 135.929 80.664  1.00 99.70  ? 314 GLU A CB  1 
ATOM   1991 C  CG  . GLU A 1 314 ? 107.003 134.675 81.297  1.00 99.70  ? 314 GLU A CG  1 
ATOM   1992 C  CD  . GLU A 1 314 ? 107.504 133.679 80.268  1.00 99.70  ? 314 GLU A CD  1 
ATOM   1993 O  OE1 . GLU A 1 314 ? 108.359 134.055 79.440  1.00 99.70  ? 314 GLU A OE1 1 
ATOM   1994 O  OE2 . GLU A 1 314 ? 107.041 132.519 80.288  1.00 99.70  ? 314 GLU A OE2 1 
ATOM   1995 N  N   . MET A 1 315 ? 109.326 136.948 81.977  1.00 97.03  ? 315 MET A N   1 
ATOM   1996 C  CA  . MET A 1 315 ? 110.097 137.372 83.139  1.00 97.03  ? 315 MET A CA  1 
ATOM   1997 C  C   . MET A 1 315 ? 110.432 138.857 83.068  1.00 97.03  ? 315 MET A C   1 
ATOM   1998 O  O   . MET A 1 315 ? 110.329 139.578 84.067  1.00 97.03  ? 315 MET A O   1 
ATOM   1999 C  CB  . MET A 1 315 ? 111.375 136.538 83.237  1.00 97.03  ? 315 MET A CB  1 
ATOM   2000 C  CG  . MET A 1 315 ? 112.367 137.033 84.269  1.00 97.03  ? 315 MET A CG  1 
ATOM   2001 S  SD  . MET A 1 315 ? 112.196 136.177 85.839  1.00 97.03  ? 315 MET A SD  1 
ATOM   2002 C  CE  . MET A 1 315 ? 113.010 134.629 85.460  1.00 97.03  ? 315 MET A CE  1 
ATOM   2003 N  N   . PHE A 1 316 ? 110.841 139.330 81.888  1.00 100.01 ? 316 PHE A N   1 
ATOM   2004 C  CA  . PHE A 1 316 ? 111.287 140.713 81.752  1.00 100.01 ? 316 PHE A CA  1 
ATOM   2005 C  C   . PHE A 1 316 ? 110.152 141.696 82.011  1.00 100.01 ? 316 PHE A C   1 
ATOM   2006 O  O   . PHE A 1 316 ? 110.354 142.729 82.660  1.00 100.01 ? 316 PHE A O   1 
ATOM   2007 C  CB  . PHE A 1 316 ? 111.885 140.934 80.363  1.00 100.01 ? 316 PHE A CB  1 
ATOM   2008 C  CG  . PHE A 1 316 ? 112.620 142.235 80.220  1.00 100.01 ? 316 PHE A CG  1 
ATOM   2009 C  CD1 . PHE A 1 316 ? 113.888 142.390 80.754  1.00 100.01 ? 316 PHE A CD1 1 
ATOM   2010 C  CD2 . PHE A 1 316 ? 112.043 143.303 79.553  1.00 100.01 ? 316 PHE A CD2 1 
ATOM   2011 C  CE1 . PHE A 1 316 ? 114.568 143.586 80.625  1.00 100.01 ? 316 PHE A CE1 1 
ATOM   2012 C  CE2 . PHE A 1 316 ? 112.719 144.502 79.420  1.00 100.01 ? 316 PHE A CE2 1 
ATOM   2013 C  CZ  . PHE A 1 316 ? 113.983 144.643 79.957  1.00 100.01 ? 316 PHE A CZ  1 
ATOM   2014 N  N   . LYS A 1 317 ? 108.957 141.396 81.514  1.00 99.89  ? 317 LYS A N   1 
ATOM   2015 C  CA  . LYS A 1 317 ? 107.808 142.275 81.703  1.00 99.89  ? 317 LYS A CA  1 
ATOM   2016 C  C   . LYS A 1 317 ? 107.132 142.007 83.043  1.00 99.89  ? 317 LYS A C   1 
ATOM   2017 O  O   . LYS A 1 317 ? 107.672 141.295 83.889  1.00 99.89  ? 317 LYS A O   1 
ATOM   2018 C  CB  . LYS A 1 317 ? 106.806 142.100 80.562  1.00 99.89  ? 317 LYS A CB  1 
ATOM   2019 C  CG  . LYS A 1 317 ? 107.436 142.105 79.179  1.00 99.89  ? 317 LYS A CG  1 
ATOM   2020 C  CD  . LYS A 1 317 ? 106.500 141.505 78.143  1.00 99.89  ? 317 LYS A CD  1 
ATOM   2021 C  CE  . LYS A 1 317 ? 107.174 141.406 76.785  1.00 99.89  ? 317 LYS A CE  1 
ATOM   2022 N  NZ  . LYS A 1 317 ? 106.222 140.982 75.722  1.00 99.89  ? 317 LYS A NZ  1 
ATOM   2023 N  N   . LYS A 1 322 ? 98.124  145.562 83.799  1.00 95.14  ? 322 LYS A N   1 
ATOM   2024 C  CA  . LYS A 1 322 ? 98.330  144.631 84.902  1.00 95.14  ? 322 LYS A CA  1 
ATOM   2025 C  C   . LYS A 1 322 ? 97.291  143.515 84.884  1.00 95.14  ? 322 LYS A C   1 
ATOM   2026 O  O   . LYS A 1 322 ? 96.173  143.703 84.406  1.00 95.14  ? 322 LYS A O   1 
ATOM   2027 C  CB  . LYS A 1 322 ? 98.285  145.369 86.241  1.00 95.14  ? 322 LYS A CB  1 
ATOM   2028 C  CG  . LYS A 1 322 ? 99.507  146.227 86.523  1.00 95.14  ? 322 LYS A CG  1 
ATOM   2029 C  CD  . LYS A 1 322 ? 100.729 145.371 86.816  1.00 95.14  ? 322 LYS A CD  1 
ATOM   2030 C  CE  . LYS A 1 322 ? 101.838 146.190 87.458  1.00 95.14  ? 322 LYS A CE  1 
ATOM   2031 N  NZ  . LYS A 1 322 ? 103.045 145.367 87.739  1.00 95.14  ? 322 LYS A NZ  1 
ATOM   2032 N  N   . THR A 1 323 ? 97.673  142.354 85.407  1.00 94.56  ? 323 THR A N   1 
ATOM   2033 C  CA  . THR A 1 323 ? 96.758  141.225 85.491  1.00 94.56  ? 323 THR A CA  1 
ATOM   2034 C  C   . THR A 1 323 ? 95.620  141.542 86.457  1.00 94.56  ? 323 THR A C   1 
ATOM   2035 O  O   . THR A 1 323 ? 95.777  142.320 87.402  1.00 94.56  ? 323 THR A O   1 
ATOM   2036 C  CB  . THR A 1 323 ? 97.506  139.968 85.941  1.00 94.56  ? 323 THR A CB  1 
ATOM   2037 O  OG1 . THR A 1 323 ? 98.724  139.846 85.196  1.00 94.56  ? 323 THR A OG1 1 
ATOM   2038 C  CG2 . THR A 1 323 ? 96.665  138.720 85.708  1.00 94.56  ? 323 THR A CG2 1 
ATOM   2039 N  N   . VAL A 1 324 ? 94.458  140.935 86.202  1.00 92.73  ? 324 VAL A N   1 
ATOM   2040 C  CA  . VAL A 1 324 ? 93.283  141.188 87.033  1.00 92.73  ? 324 VAL A CA  1 
ATOM   2041 C  C   . VAL A 1 324 ? 93.556  140.793 88.478  1.00 92.73  ? 324 VAL A C   1 
ATOM   2042 O  O   . VAL A 1 324 ? 93.218  141.529 89.414  1.00 92.73  ? 324 VAL A O   1 
ATOM   2043 C  CB  . VAL A 1 324 ? 92.057  140.450 86.464  1.00 92.73  ? 324 VAL A CB  1 
ATOM   2044 C  CG1 . VAL A 1 324 ? 90.853  140.636 87.375  1.00 92.73  ? 324 VAL A CG1 1 
ATOM   2045 C  CG2 . VAL A 1 324 ? 91.750  140.940 85.058  1.00 92.73  ? 324 VAL A CG2 1 
ATOM   2046 N  N   . GLN A 1 325 ? 94.173  139.629 88.685  1.00 93.28  ? 325 GLN A N   1 
ATOM   2047 C  CA  . GLN A 1 325 ? 94.518  139.213 90.040  1.00 93.28  ? 325 GLN A CA  1 
ATOM   2048 C  C   . GLN A 1 325 ? 95.689  140.014 90.596  1.00 93.28  ? 325 GLN A C   1 
ATOM   2049 O  O   . GLN A 1 325 ? 95.827  140.137 91.818  1.00 93.28  ? 325 GLN A O   1 
ATOM   2050 C  CB  . GLN A 1 325 ? 94.832  137.716 90.064  1.00 93.28  ? 325 GLN A CB  1 
ATOM   2051 C  CG  . GLN A 1 325 ? 96.107  137.328 89.327  1.00 93.28  ? 325 GLN A CG  1 
ATOM   2052 C  CD  . GLN A 1 325 ? 97.332  137.339 90.223  1.00 93.28  ? 325 GLN A CD  1 
ATOM   2053 O  OE1 . GLN A 1 325 ? 97.282  136.887 91.366  1.00 93.28  ? 325 GLN A OE1 1 
ATOM   2054 N  NE2 . GLN A 1 325 ? 98.436  137.867 89.709  1.00 93.28  ? 325 GLN A NE2 1 
ATOM   2055 N  N   . GLN A 1 326 ? 96.542  140.557 89.722  1.00 92.22  ? 326 GLN A N   1 
ATOM   2056 C  CA  . GLN A 1 326 ? 97.740  141.248 90.188  1.00 92.22  ? 326 GLN A CA  1 
ATOM   2057 C  C   . GLN A 1 326 ? 97.392  142.514 90.962  1.00 92.22  ? 326 GLN A C   1 
ATOM   2058 O  O   . GLN A 1 326 ? 97.938  142.759 92.045  1.00 92.22  ? 326 GLN A O   1 
ATOM   2059 C  CB  . GLN A 1 326 ? 98.648  141.575 89.002  1.00 92.22  ? 326 GLN A CB  1 
ATOM   2060 C  CG  . GLN A 1 326 ? 100.114 141.738 89.366  1.00 92.22  ? 326 GLN A CG  1 
ATOM   2061 C  CD  . GLN A 1 326 ? 101.003 141.888 88.148  1.00 92.22  ? 326 GLN A CD  1 
ATOM   2062 O  OE1 . GLN A 1 326 ? 100.519 142.084 87.033  1.00 92.22  ? 326 GLN A OE1 1 
ATOM   2063 N  NE2 . GLN A 1 326 ? 102.311 141.795 88.354  1.00 92.22  ? 326 GLN A NE2 1 
ATOM   2064 N  N   . LYS A 1 327 ? 96.486  143.333 90.422  1.00 91.43  ? 327 LYS A N   1 
ATOM   2065 C  CA  . LYS A 1 327 ? 96.098  144.552 91.124  1.00 91.43  ? 327 LYS A CA  1 
ATOM   2066 C  C   . LYS A 1 327 ? 95.359  144.234 92.416  1.00 91.43  ? 327 LYS A C   1 
ATOM   2067 O  O   . LYS A 1 327 ? 95.523  144.939 93.417  1.00 91.43  ? 327 LYS A O   1 
ATOM   2068 C  CB  . LYS A 1 327 ? 95.253  145.450 90.220  1.00 91.43  ? 327 LYS A CB  1 
ATOM   2069 C  CG  . LYS A 1 327 ? 94.355  144.725 89.233  1.00 91.43  ? 327 LYS A CG  1 
ATOM   2070 C  CD  . LYS A 1 327 ? 93.791  145.711 88.218  1.00 91.43  ? 327 LYS A CD  1 
ATOM   2071 C  CE  . LYS A 1 327 ? 93.077  145.009 87.076  1.00 91.43  ? 327 LYS A CE  1 
ATOM   2072 N  NZ  . LYS A 1 327 ? 94.027  144.248 86.223  1.00 91.43  ? 327 LYS A NZ  1 
ATOM   2073 N  N   . ALA A 1 328 ? 94.544  143.177 92.419  1.00 88.44  ? 328 ALA A N   1 
ATOM   2074 C  CA  . ALA A 1 328 ? 93.870  142.771 93.649  1.00 88.44  ? 328 ALA A CA  1 
ATOM   2075 C  C   . ALA A 1 328 ? 94.873  142.350 94.716  1.00 88.44  ? 328 ALA A C   1 
ATOM   2076 O  O   . ALA A 1 328 ? 94.724  142.703 95.893  1.00 88.44  ? 328 ALA A O   1 
ATOM   2077 C  CB  . ALA A 1 328 ? 92.885  141.640 93.359  1.00 88.44  ? 328 ALA A CB  1 
ATOM   2078 N  N   . CYS A 1 329 ? 95.900  141.591 94.325  1.00 87.97  ? 329 CYS A N   1 
ATOM   2079 C  CA  . CYS A 1 329 ? 96.926  141.185 95.281  1.00 87.97  ? 329 CYS A CA  1 
ATOM   2080 C  C   . CYS A 1 329 ? 97.704  142.386 95.802  1.00 87.97  ? 329 CYS A C   1 
ATOM   2081 O  O   . CYS A 1 329 ? 97.992  142.477 97.002  1.00 87.97  ? 329 CYS A O   1 
ATOM   2082 C  CB  . CYS A 1 329 ? 97.871  140.170 94.639  1.00 87.97  ? 329 CYS A CB  1 
ATOM   2083 S  SG  . CYS A 1 329 ? 97.120  138.557 94.340  1.00 87.97  ? 329 CYS A SG  1 
ATOM   2084 N  N   . ALA A 1 330 ? 98.053  143.320 94.915  1.00 80.49  ? 330 ALA A N   1 
ATOM   2085 C  CA  . ALA A 1 330 ? 98.736  144.530 95.362  1.00 80.49  ? 330 ALA A CA  1 
ATOM   2086 C  C   . ALA A 1 330 ? 97.869  145.312 96.339  1.00 80.49  ? 330 ALA A C   1 
ATOM   2087 O  O   . ALA A 1 330 ? 98.356  145.791 97.372  1.00 80.49  ? 330 ALA A O   1 
ATOM   2088 C  CB  . ALA A 1 330 ? 99.113  145.396 94.161  1.00 80.49  ? 330 ALA A CB  1 
ATOM   2089 N  N   . GLU A 1 331 ? 96.573  145.426 96.044  1.00 79.33  ? 331 GLU A N   1 
ATOM   2090 C  CA  . GLU A 1 331 ? 95.670  146.148 96.929  1.00 79.33  ? 331 GLU A CA  1 
ATOM   2091 C  C   . GLU A 1 331 ? 95.573  145.480 98.294  1.00 79.33  ? 331 GLU A C   1 
ATOM   2092 O  O   . GLU A 1 331 ? 95.653  146.160 99.323  1.00 79.33  ? 331 GLU A O   1 
ATOM   2093 C  CB  . GLU A 1 331 ? 94.287  146.262 96.285  1.00 79.33  ? 331 GLU A CB  1 
ATOM   2094 C  CG  . GLU A 1 331 ? 93.389  147.389 96.818  1.00 79.33  ? 331 GLU A CG  1 
ATOM   2095 C  CD  . GLU A 1 331 ? 93.997  148.790 96.744  1.00 79.33  ? 331 GLU A CD  1 
ATOM   2096 O  OE1 . GLU A 1 331 ? 93.307  149.742 97.163  1.00 79.33  ? 331 GLU A OE1 1 
ATOM   2097 O  OE2 . GLU A 1 331 ? 95.128  148.963 96.241  1.00 79.33  ? 331 GLU A OE2 1 
ATOM   2098 N  N   . VAL A 1 332 ? 95.408  144.154 98.329  1.00 72.71  ? 332 VAL A N   1 
ATOM   2099 C  CA  . VAL A 1 332 ? 95.255  143.477 99.615  1.00 72.71  ? 332 VAL A CA  1 
ATOM   2100 C  C   . VAL A 1 332 ? 96.548  143.553 100.419 1.00 72.71  ? 332 VAL A C   1 
ATOM   2101 O  O   . VAL A 1 332 ? 96.521  143.698 101.648 1.00 72.71  ? 332 VAL A O   1 
ATOM   2102 C  CB  . VAL A 1 332 ? 94.771  142.026 99.428  1.00 72.71  ? 332 VAL A CB  1 
ATOM   2103 C  CG1 . VAL A 1 332 ? 95.795  141.183 98.705  1.00 72.71  ? 332 VAL A CG1 1 
ATOM   2104 C  CG2 . VAL A 1 332 ? 94.453  141.416 100.776 1.00 72.71  ? 332 VAL A CG2 1 
ATOM   2105 N  N   . ILE A 1 333 ? 97.700  143.488 99.744  1.00 67.70  ? 333 ILE A N   1 
ATOM   2106 C  CA  . ILE A 1 333 ? 98.964  143.732 100.430 1.00 67.70  ? 333 ILE A CA  1 
ATOM   2107 C  C   . ILE A 1 333 ? 98.984  145.143 101.002 1.00 67.70  ? 333 ILE A C   1 
ATOM   2108 O  O   . ILE A 1 333 ? 99.505  145.381 102.099 1.00 67.70  ? 333 ILE A O   1 
ATOM   2109 C  CB  . ILE A 1 333 ? 100.147 143.481 99.476  1.00 67.70  ? 333 ILE A CB  1 
ATOM   2110 C  CG1 . ILE A 1 333 ? 100.324 141.981 99.238  1.00 67.70  ? 333 ILE A CG1 1 
ATOM   2111 C  CG2 . ILE A 1 333 ? 101.428 144.074 100.032 1.00 67.70  ? 333 ILE A CG2 1 
ATOM   2112 C  CD1 . ILE A 1 333 ? 100.422 141.173 100.510 1.00 67.70  ? 333 ILE A CD1 1 
ATOM   2113 N  N   . LYS A 1 334 ? 98.399  146.099 100.277 1.00 65.91  ? 334 LYS A N   1 
ATOM   2114 C  CA  . LYS A 1 334 ? 98.341  147.469 100.774 1.00 65.91  ? 334 LYS A CA  1 
ATOM   2115 C  C   . LYS A 1 334 ? 97.499  147.566 102.046 1.00 65.91  ? 334 LYS A C   1 
ATOM   2116 O  O   . LYS A 1 334 ? 97.902  148.217 103.021 1.00 65.91  ? 334 LYS A O   1 
ATOM   2117 C  CB  . LYS A 1 334 ? 97.798  148.393 99.682  1.00 65.91  ? 334 LYS A CB  1 
ATOM   2118 C  CG  . LYS A 1 334 ? 97.913  149.871 99.995  1.00 65.91  ? 334 LYS A CG  1 
ATOM   2119 C  CD  . LYS A 1 334 ? 99.365  150.313 100.044 1.00 65.91  ? 334 LYS A CD  1 
ATOM   2120 C  CE  . LYS A 1 334 ? 99.996  150.280 98.662  1.00 65.91  ? 334 LYS A CE  1 
ATOM   2121 N  NZ  . LYS A 1 334 ? 99.428  151.322 97.763  1.00 65.91  ? 334 LYS A NZ  1 
ATOM   2122 N  N   . GLN A 1 335 ? 96.317  146.936 102.059 1.00 68.01  ? 335 GLN A N   1 
ATOM   2123 C  CA  . GLN A 1 335 ? 95.517  147.001 103.285 1.00 68.01  ? 335 GLN A CA  1 
ATOM   2124 C  C   . GLN A 1 335 ? 96.204  146.270 104.431 1.00 68.01  ? 335 GLN A C   1 
ATOM   2125 O  O   . GLN A 1 335 ? 96.085  146.684 105.588 1.00 68.01  ? 335 GLN A O   1 
ATOM   2126 C  CB  . GLN A 1 335 ? 94.079  146.477 103.135 1.00 68.01  ? 335 GLN A CB  1 
ATOM   2127 C  CG  . GLN A 1 335 ? 93.111  147.313 102.290 1.00 68.01  ? 335 GLN A CG  1 
ATOM   2128 C  CD  . GLN A 1 335 ? 93.091  146.957 100.832 1.00 68.01  ? 335 GLN A CD  1 
ATOM   2129 O  OE1 . GLN A 1 335 ? 93.480  145.860 100.456 1.00 68.01  ? 335 GLN A OE1 1 
ATOM   2130 N  NE2 . GLN A 1 335 ? 92.632  147.881 99.998  1.00 68.01  ? 335 GLN A NE2 1 
ATOM   2131 N  N   . GLU A 1 336 ? 96.935  145.192 104.139 1.00 61.19  ? 336 GLU A N   1 
ATOM   2132 C  CA  . GLU A 1 336 ? 97.717  144.553 105.195 1.00 61.19  ? 336 GLU A CA  1 
ATOM   2133 C  C   . GLU A 1 336 ? 98.776  145.503 105.742 1.00 61.19  ? 336 GLU A C   1 
ATOM   2134 O  O   . GLU A 1 336 ? 99.000  145.568 106.959 1.00 61.19  ? 336 GLU A O   1 
ATOM   2135 C  CB  . GLU A 1 336 ? 98.362  143.268 104.680 1.00 61.19  ? 336 GLU A CB  1 
ATOM   2136 C  CG  . GLU A 1 336 ? 97.374  142.184 104.290 1.00 61.19  ? 336 GLU A CG  1 
ATOM   2137 C  CD  . GLU A 1 336 ? 96.569  141.681 105.471 1.00 61.19  ? 336 GLU A CD  1 
ATOM   2138 O  OE1 . GLU A 1 336 ? 97.036  140.745 106.153 1.00 61.19  ? 336 GLU A OE1 1 
ATOM   2139 O  OE2 . GLU A 1 336 ? 95.470  142.219 105.716 1.00 61.19  ? 336 GLU A OE2 1 
ATOM   2140 N  N   . TYR A 1 337 ? 99.432  146.255 104.856 1.00 53.99  ? 337 TYR A N   1 
ATOM   2141 C  CA  . TYR A 1 337 ? 100.469 147.181 105.298 1.00 53.99  ? 337 TYR A CA  1 
ATOM   2142 C  C   . TYR A 1 337 ? 99.894  148.280 106.184 1.00 53.99  ? 337 TYR A C   1 
ATOM   2143 O  O   . TYR A 1 337 ? 100.500 148.646 107.197 1.00 53.99  ? 337 TYR A O   1 
ATOM   2144 C  CB  . TYR A 1 337 ? 101.192 147.780 104.093 1.00 53.99  ? 337 TYR A CB  1 
ATOM   2145 C  CG  . TYR A 1 337 ? 102.497 148.444 104.458 1.00 53.99  ? 337 TYR A CG  1 
ATOM   2146 C  CD1 . TYR A 1 337 ? 103.642 147.692 104.676 1.00 53.99  ? 337 TYR A CD1 1 
ATOM   2147 C  CD2 . TYR A 1 337 ? 102.582 149.821 104.595 1.00 53.99  ? 337 TYR A CD2 1 
ATOM   2148 C  CE1 . TYR A 1 337 ? 104.836 148.292 105.016 1.00 53.99  ? 337 TYR A CE1 1 
ATOM   2149 C  CE2 . TYR A 1 337 ? 103.773 150.431 104.935 1.00 53.99  ? 337 TYR A CE2 1 
ATOM   2150 C  CZ  . TYR A 1 337 ? 104.896 149.661 105.144 1.00 53.99  ? 337 TYR A CZ  1 
ATOM   2151 O  OH  . TYR A 1 337 ? 106.082 150.267 105.483 1.00 53.99  ? 337 TYR A OH  1 
ATOM   2152 N  N   . GLN A 1 338 ? 98.729  148.826 105.821 1.00 60.95  ? 338 GLN A N   1 
ATOM   2153 C  CA  . GLN A 1 338 ? 98.100  149.790 106.727 1.00 60.95  ? 338 GLN A CA  1 
ATOM   2154 C  C   . GLN A 1 338 ? 97.582  149.129 108.000 1.00 60.95  ? 338 GLN A C   1 
ATOM   2155 O  O   . GLN A 1 338 ? 97.519  149.782 109.048 1.00 60.95  ? 338 GLN A O   1 
ATOM   2156 C  CB  . GLN A 1 338 ? 96.972  150.574 106.052 1.00 60.95  ? 338 GLN A CB  1 
ATOM   2157 C  CG  . GLN A 1 338 ? 97.425  151.628 105.050 1.00 60.95  ? 338 GLN A CG  1 
ATOM   2158 C  CD  . GLN A 1 338 ? 98.015  151.050 103.796 1.00 60.95  ? 338 GLN A CD  1 
ATOM   2159 O  OE1 . GLN A 1 338 ? 99.175  151.290 103.465 1.00 60.95  ? 338 GLN A OE1 1 
ATOM   2160 N  NE2 . GLN A 1 338 ? 97.199  150.317 103.059 1.00 60.95  ? 338 GLN A NE2 1 
ATOM   2161 N  N   . LYS A 1 339 ? 97.202  147.851 107.938 1.00 58.17  ? 339 LYS A N   1 
ATOM   2162 C  CA  . LYS A 1 339 ? 96.797  147.150 109.152 1.00 58.17  ? 339 LYS A CA  1 
ATOM   2163 C  C   . LYS A 1 339 ? 97.968  146.973 110.106 1.00 58.17  ? 339 LYS A C   1 
ATOM   2164 O  O   . LYS A 1 339 ? 97.766  146.876 111.321 1.00 58.17  ? 339 LYS A O   1 
ATOM   2165 C  CB  . LYS A 1 339 ? 96.185  145.794 108.803 1.00 58.17  ? 339 LYS A CB  1 
ATOM   2166 C  CG  . LYS A 1 339 ? 95.088  145.352 109.756 1.00 58.17  ? 339 LYS A CG  1 
ATOM   2167 C  CD  . LYS A 1 339 ? 94.545  143.984 109.383 1.00 58.17  ? 339 LYS A CD  1 
ATOM   2168 C  CE  . LYS A 1 339 ? 93.952  143.988 107.986 1.00 58.17  ? 339 LYS A CE  1 
ATOM   2169 N  NZ  . LYS A 1 339 ? 92.798  143.055 107.876 1.00 58.17  ? 339 LYS A NZ  1 
ATOM   2170 N  N   . LEU A 1 340 ? 99.192  146.921 109.577 1.00 49.24  ? 340 LEU A N   1 
ATOM   2171 C  CA  . LEU A 1 340 ? 100.363 146.910 110.448 1.00 49.24  ? 340 LEU A CA  1 
ATOM   2172 C  C   . LEU A 1 340 ? 100.448 148.192 111.267 1.00 49.24  ? 340 LEU A C   1 
ATOM   2173 O  O   . LEU A 1 340 ? 100.815 148.161 112.448 1.00 49.24  ? 340 LEU A O   1 
ATOM   2174 C  CB  . LEU A 1 340 ? 101.635 146.719 109.623 1.00 49.24  ? 340 LEU A CB  1 
ATOM   2175 C  CG  . LEU A 1 340 ? 101.971 145.278 109.245 1.00 49.24  ? 340 LEU A CG  1 
ATOM   2176 C  CD1 . LEU A 1 340 ? 103.233 145.237 108.411 1.00 49.24  ? 340 LEU A CD1 1 
ATOM   2177 C  CD2 . LEU A 1 340 ? 102.122 144.426 110.490 1.00 49.24  ? 340 LEU A CD2 1 
ATOM   2178 N  N   . GLY A 1 341 ? 100.113 149.326 110.660 1.00 49.68  ? 341 GLY A N   1 
ATOM   2179 C  CA  . GLY A 1 341 ? 100.128 150.594 111.348 1.00 49.68  ? 341 GLY A CA  1 
ATOM   2180 C  C   . GLY A 1 341 ? 101.425 151.348 111.145 1.00 49.68  ? 341 GLY A C   1 
ATOM   2181 O  O   . GLY A 1 341 ? 102.384 150.837 110.557 1.00 49.68  ? 341 GLY A O   1 
ATOM   2182 N  N   . PRO A 1 342 ? 101.475 152.589 111.622 1.00 45.38  ? 342 PRO A N   1 
ATOM   2183 C  CA  . PRO A 1 342 ? 102.707 153.375 111.503 1.00 45.38  ? 342 PRO A CA  1 
ATOM   2184 C  C   . PRO A 1 342 ? 103.823 152.788 112.349 1.00 45.38  ? 342 PRO A C   1 
ATOM   2185 O  O   . PRO A 1 342 ? 103.585 152.101 113.345 1.00 45.38  ? 342 PRO A O   1 
ATOM   2186 C  CB  . PRO A 1 342 ? 102.298 154.764 112.011 1.00 45.38  ? 342 PRO A CB  1 
ATOM   2187 C  CG  . PRO A 1 342 ? 100.800 154.773 111.971 1.00 45.38  ? 342 PRO A CG  1 
ATOM   2188 C  CD  . PRO A 1 342 ? 100.386 153.363 112.237 1.00 45.38  ? 342 PRO A CD  1 
ATOM   2189 N  N   . ILE A 1 343 ? 105.062 153.063 111.931 1.00 39.23  ? 343 ILE A N   1 
ATOM   2190 C  CA  . ILE A 1 343 ? 106.216 152.582 112.678 1.00 39.23  ? 343 ILE A CA  1 
ATOM   2191 C  C   . ILE A 1 343 ? 106.194 153.180 114.077 1.00 39.23  ? 343 ILE A C   1 
ATOM   2192 O  O   . ILE A 1 343 ? 105.826 154.345 114.276 1.00 39.23  ? 343 ILE A O   1 
ATOM   2193 C  CB  . ILE A 1 343 ? 107.521 152.909 111.931 1.00 39.23  ? 343 ILE A CB  1 
ATOM   2194 C  CG1 . ILE A 1 343 ? 108.686 152.104 112.509 1.00 39.23  ? 343 ILE A CG1 1 
ATOM   2195 C  CG2 . ILE A 1 343 ? 107.819 154.402 111.961 1.00 39.23  ? 343 ILE A CG2 1 
ATOM   2196 C  CD1 . ILE A 1 343 ? 109.879 152.014 111.585 1.00 39.23  ? 343 ILE A CD1 1 
ATOM   2197 N  N   . ARG A 1 344 ? 106.558 152.368 115.063 1.00 35.86  ? 344 ARG A N   1 
ATOM   2198 C  CA  . ARG A 1 344 ? 106.408 152.728 116.462 1.00 35.86  ? 344 ARG A CA  1 
ATOM   2199 C  C   . ARG A 1 344 ? 107.683 152.396 117.222 1.00 35.86  ? 344 ARG A C   1 
ATOM   2200 O  O   . ARG A 1 344 ? 108.659 151.891 116.661 1.00 35.86  ? 344 ARG A O   1 
ATOM   2201 C  CB  . ARG A 1 344 ? 105.211 152.002 117.091 1.00 35.86  ? 344 ARG A CB  1 
ATOM   2202 C  CG  . ARG A 1 344 ? 105.418 150.505 117.224 1.00 35.86  ? 344 ARG A CG  1 
ATOM   2203 C  CD  . ARG A 1 344 ? 104.107 149.745 117.245 1.00 35.86  ? 344 ARG A CD  1 
ATOM   2204 N  NE  . ARG A 1 344 ? 104.199 148.533 118.051 1.00 35.86  ? 344 ARG A NE  1 
ATOM   2205 C  CZ  . ARG A 1 344 ? 104.774 147.407 117.649 1.00 35.86  ? 344 ARG A CZ  1 
ATOM   2206 N  NH1 . ARG A 1 344 ? 105.339 147.306 116.457 1.00 35.86  ? 344 ARG A NH1 1 
ATOM   2207 N  NH2 . ARG A 1 344 ? 104.784 146.357 118.465 1.00 35.86  ? 344 ARG A NH2 1 
ATOM   2208 N  N   . TYR A 1 345 ? 107.660 152.685 118.520 1.00 33.35  ? 345 TYR A N   1 
ATOM   2209 C  CA  . TYR A 1 345 ? 108.755 152.302 119.394 1.00 33.35  ? 345 TYR A CA  1 
ATOM   2210 C  C   . TYR A 1 345 ? 108.805 150.778 119.510 1.00 33.35  ? 345 TYR A C   1 
ATOM   2211 O  O   . TYR A 1 345 ? 107.922 150.064 119.028 1.00 33.35  ? 345 TYR A O   1 
ATOM   2212 C  CB  . TYR A 1 345 ? 108.600 152.968 120.761 1.00 33.35  ? 345 TYR A CB  1 
ATOM   2213 C  CG  . TYR A 1 345 ? 109.808 152.835 121.658 1.00 33.35  ? 345 TYR A CG  1 
ATOM   2214 C  CD1 . TYR A 1 345 ? 111.062 153.246 121.230 1.00 33.35  ? 345 TYR A CD1 1 
ATOM   2215 C  CD2 . TYR A 1 345 ? 109.693 152.303 122.935 1.00 33.35  ? 345 TYR A CD2 1 
ATOM   2216 C  CE1 . TYR A 1 345 ? 112.169 153.125 122.046 1.00 33.35  ? 345 TYR A CE1 1 
ATOM   2217 C  CE2 . TYR A 1 345 ? 110.794 152.179 123.757 1.00 33.35  ? 345 TYR A CE2 1 
ATOM   2218 C  CZ  . TYR A 1 345 ? 112.028 152.591 123.308 1.00 33.35  ? 345 TYR A CZ  1 
ATOM   2219 O  OH  . TYR A 1 345 ? 113.127 152.469 124.126 1.00 33.35  ? 345 TYR A OH  1 
ATOM   2220 N  N   . GLN A 1 346 ? 109.882 150.282 120.125 1.00 28.62  ? 346 GLN A N   1 
ATOM   2221 C  CA  . GLN A 1 346 ? 110.248 148.867 120.141 1.00 28.62  ? 346 GLN A CA  1 
ATOM   2222 C  C   . GLN A 1 346 ? 110.664 148.432 118.740 1.00 28.62  ? 346 GLN A C   1 
ATOM   2223 O  O   . GLN A 1 346 ? 111.112 147.300 118.533 1.00 28.62  ? 346 GLN A O   1 
ATOM   2224 C  CB  . GLN A 1 346 ? 109.116 147.981 120.673 1.00 28.62  ? 346 GLN A CB  1 
ATOM   2225 C  CG  . GLN A 1 346 ? 108.782 148.197 122.140 1.00 28.62  ? 346 GLN A CG  1 
ATOM   2226 C  CD  . GLN A 1 346 ? 107.675 149.209 122.350 1.00 28.62  ? 346 GLN A CD  1 
ATOM   2227 O  OE1 . GLN A 1 346 ? 106.866 149.455 121.459 1.00 28.62  ? 346 GLN A OE1 1 
ATOM   2228 N  NE2 . GLN A 1 346 ? 107.635 149.802 123.535 1.00 28.62  ? 346 GLN A NE2 1 
ATOM   2229 N  N   . GLU A 1 347 ? 110.510 149.333 117.781 1.00 32.18  ? 347 GLU A N   1 
ATOM   2230 C  CA  . GLU A 1 347 ? 111.153 149.309 116.478 1.00 32.18  ? 347 GLU A CA  1 
ATOM   2231 C  C   . GLU A 1 347 ? 112.008 150.569 116.397 1.00 32.18  ? 347 GLU A C   1 
ATOM   2232 O  O   . GLU A 1 347 ? 112.186 151.274 117.396 1.00 32.18  ? 347 GLU A O   1 
ATOM   2233 C  CB  . GLU A 1 347 ? 110.121 149.223 115.353 1.00 32.18  ? 347 GLU A CB  1 
ATOM   2234 C  CG  . GLU A 1 347 ? 109.224 148.002 115.428 1.00 32.18  ? 347 GLU A CG  1 
ATOM   2235 C  CD  . GLU A 1 347 ? 108.165 147.992 114.345 1.00 32.18  ? 347 GLU A CD  1 
ATOM   2236 O  OE1 . GLU A 1 347 ? 108.274 148.798 113.398 1.00 32.18  ? 347 GLU A OE1 1 
ATOM   2237 O  OE2 . GLU A 1 347 ? 107.221 147.181 114.440 1.00 32.18  ? 347 GLU A OE2 1 
ATOM   2238 N  N   . ILE A 1 348 ? 112.551 150.848 115.213 1.00 27.18  ? 348 ILE A N   1 
ATOM   2239 C  CA  . ILE A 1 348 ? 113.464 151.973 115.018 1.00 27.18  ? 348 ILE A CA  1 
ATOM   2240 C  C   . ILE A 1 348 ? 114.713 151.754 115.862 1.00 27.18  ? 348 ILE A C   1 
ATOM   2241 O  O   . ILE A 1 348 ? 115.830 151.721 115.335 1.00 27.18  ? 348 ILE A O   1 
ATOM   2242 C  CB  . ILE A 1 348 ? 112.802 153.324 115.353 1.00 27.18  ? 348 ILE A CB  1 
ATOM   2243 C  CG1 . ILE A 1 348 ? 111.638 153.605 114.404 1.00 27.18  ? 348 ILE A CG1 1 
ATOM   2244 C  CG2 . ILE A 1 348 ? 113.820 154.446 115.294 1.00 27.18  ? 348 ILE A CG2 1 
ATOM   2245 C  CD1 . ILE A 1 348 ? 110.816 154.806 114.799 1.00 27.18  ? 348 ILE A CD1 1 
ATOM   2246 N  N   . VAL A 1 349 ? 114.534 151.604 117.178 1.00 24.15  ? 349 VAL A N   1 
ATOM   2247 C  CA  . VAL A 1 349 ? 115.655 151.270 118.050 1.00 24.15  ? 349 VAL A CA  1 
ATOM   2248 C  C   . VAL A 1 349 ? 116.263 149.935 117.646 1.00 24.15  ? 349 VAL A C   1 
ATOM   2249 O  O   . VAL A 1 349 ? 117.484 149.756 117.711 1.00 24.15  ? 349 VAL A O   1 
ATOM   2250 C  CB  . VAL A 1 349 ? 115.214 151.281 119.529 1.00 24.15  ? 349 VAL A CB  1 
ATOM   2251 C  CG1 . VAL A 1 349 ? 114.079 150.303 119.768 1.00 24.15  ? 349 VAL A CG1 1 
ATOM   2252 C  CG2 . VAL A 1 349 ? 116.389 150.968 120.439 1.00 24.15  ? 349 VAL A CG2 1 
ATOM   2253 N  N   . THR A 1 350 ? 115.435 148.981 117.214 1.00 22.85  ? 350 THR A N   1 
ATOM   2254 C  CA  . THR A 1 350 ? 115.968 147.736 116.673 1.00 22.85  ? 350 THR A CA  1 
ATOM   2255 C  C   . THR A 1 350 ? 116.749 147.990 115.389 1.00 22.85  ? 350 THR A C   1 
ATOM   2256 O  O   . THR A 1 350 ? 117.852 147.462 115.207 1.00 22.85  ? 350 THR A O   1 
ATOM   2257 C  CB  . THR A 1 350 ? 114.836 146.740 116.428 1.00 22.85  ? 350 THR A CB  1 
ATOM   2258 O  OG1 . THR A 1 350 ? 113.965 146.717 117.564 1.00 22.85  ? 350 THR A OG1 1 
ATOM   2259 C  CG2 . THR A 1 350 ? 115.397 145.350 116.205 1.00 22.85  ? 350 THR A CG2 1 
ATOM   2260 N  N   . LEU A 1 351 ? 116.196 148.809 114.490 1.00 25.60  ? 351 LEU A N   1 
ATOM   2261 C  CA  . LEU A 1 351 ? 116.920 149.176 113.277 1.00 25.60  ? 351 LEU A CA  1 
ATOM   2262 C  C   . LEU A 1 351 ? 118.188 149.952 113.603 1.00 25.60  ? 351 LEU A C   1 
ATOM   2263 O  O   . LEU A 1 351 ? 119.231 149.743 112.974 1.00 25.60  ? 351 LEU A O   1 
ATOM   2264 C  CB  . LEU A 1 351 ? 116.025 149.997 112.349 1.00 25.60  ? 351 LEU A CB  1 
ATOM   2265 C  CG  . LEU A 1 351 ? 114.628 149.469 112.036 1.00 25.60  ? 351 LEU A CG  1 
ATOM   2266 C  CD1 . LEU A 1 351 ? 113.754 150.582 111.491 1.00 25.60  ? 351 LEU A CD1 1 
ATOM   2267 C  CD2 . LEU A 1 351 ? 114.735 148.344 111.028 1.00 25.60  ? 351 LEU A CD2 1 
ATOM   2268 N  N   . VAL A 1 352 ? 118.112 150.867 114.572 1.00 23.37  ? 352 VAL A N   1 
ATOM   2269 C  CA  . VAL A 1 352 ? 119.284 151.649 114.952 1.00 23.37  ? 352 VAL A CA  1 
ATOM   2270 C  C   . VAL A 1 352 ? 120.382 150.732 115.474 1.00 23.37  ? 352 VAL A C   1 
ATOM   2271 O  O   . VAL A 1 352 ? 121.553 150.859 115.100 1.00 23.37  ? 352 VAL A O   1 
ATOM   2272 C  CB  . VAL A 1 352 ? 118.901 152.723 115.986 1.00 23.37  ? 352 VAL A CB  1 
ATOM   2273 C  CG1 . VAL A 1 352 ? 120.130 153.212 116.729 1.00 23.37  ? 352 VAL A CG1 1 
ATOM   2274 C  CG2 . VAL A 1 352 ? 118.196 153.881 115.304 1.00 23.37  ? 352 VAL A CG2 1 
ATOM   2275 N  N   . LEU A 1 353 ? 120.017 149.780 116.332 1.00 22.24  ? 353 LEU A N   1 
ATOM   2276 C  CA  . LEU A 1 353 ? 121.011 148.865 116.879 1.00 22.24  ? 353 LEU A CA  1 
ATOM   2277 C  C   . LEU A 1 353 ? 121.579 147.952 115.798 1.00 22.24  ? 353 LEU A C   1 
ATOM   2278 O  O   . LEU A 1 353 ? 122.777 147.654 115.802 1.00 22.24  ? 353 LEU A O   1 
ATOM   2279 C  CB  . LEU A 1 353 ? 120.403 148.055 118.023 1.00 22.24  ? 353 LEU A CB  1 
ATOM   2280 C  CG  . LEU A 1 353 ? 120.720 148.591 119.423 1.00 22.24  ? 353 LEU A CG  1 
ATOM   2281 C  CD1 . LEU A 1 353 ? 120.128 149.975 119.622 1.00 22.24  ? 353 LEU A CD1 1 
ATOM   2282 C  CD2 . LEU A 1 353 ? 120.221 147.646 120.499 1.00 22.24  ? 353 LEU A CD2 1 
ATOM   2283 N  N   . PHE A 1 354 ? 120.742 147.508 114.857 1.00 25.00  ? 354 PHE A N   1 
ATOM   2284 C  CA  . PHE A 1 354 ? 121.239 146.666 113.772 1.00 25.00  ? 354 PHE A CA  1 
ATOM   2285 C  C   . PHE A 1 354 ? 122.217 147.422 112.878 1.00 25.00  ? 354 PHE A C   1 
ATOM   2286 O  O   . PHE A 1 354 ? 123.273 146.888 112.508 1.00 25.00  ? 354 PHE A O   1 
ATOM   2287 C  CB  . PHE A 1 354 ? 120.070 146.127 112.950 1.00 25.00  ? 354 PHE A CB  1 
ATOM   2288 C  CG  . PHE A 1 354 ? 120.476 145.560 111.622 1.00 25.00  ? 354 PHE A CG  1 
ATOM   2289 C  CD1 . PHE A 1 354 ? 121.323 144.469 111.550 1.00 25.00  ? 354 PHE A CD1 1 
ATOM   2290 C  CD2 . PHE A 1 354 ? 120.011 146.117 110.446 1.00 25.00  ? 354 PHE A CD2 1 
ATOM   2291 C  CE1 . PHE A 1 354 ? 121.698 143.946 110.331 1.00 25.00  ? 354 PHE A CE1 1 
ATOM   2292 C  CE2 . PHE A 1 354 ? 120.384 145.599 109.223 1.00 25.00  ? 354 PHE A CE2 1 
ATOM   2293 C  CZ  . PHE A 1 354 ? 121.228 144.511 109.166 1.00 25.00  ? 354 PHE A CZ  1 
ATOM   2294 N  N   . ILE A 1 355 ? 121.886 148.664 112.514 1.00 25.37  ? 355 ILE A N   1 
ATOM   2295 C  CA  . ILE A 1 355 ? 122.795 149.422 111.663 1.00 25.37  ? 355 ILE A CA  1 
ATOM   2296 C  C   . ILE A 1 355 ? 124.058 149.793 112.427 1.00 25.37  ? 355 ILE A C   1 
ATOM   2297 O  O   . ILE A 1 355 ? 125.137 149.877 111.834 1.00 25.37  ? 355 ILE A O   1 
ATOM   2298 C  CB  . ILE A 1 355 ? 122.103 150.659 111.057 1.00 25.37  ? 355 ILE A CB  1 
ATOM   2299 C  CG1 . ILE A 1 355 ? 121.733 151.677 112.134 1.00 25.37  ? 355 ILE A CG1 1 
ATOM   2300 C  CG2 . ILE A 1 355 ? 120.877 150.249 110.256 1.00 25.37  ? 355 ILE A CG2 1 
ATOM   2301 C  CD1 . ILE A 1 355 ? 121.264 153.001 111.576 1.00 25.37  ? 355 ILE A CD1 1 
ATOM   2302 N  N   . ILE A 1 356 ? 123.965 149.999 113.744 1.00 24.98  ? 356 ILE A N   1 
ATOM   2303 C  CA  . ILE A 1 356 ? 125.170 150.223 114.539 1.00 24.98  ? 356 ILE A CA  1 
ATOM   2304 C  C   . ILE A 1 356 ? 126.049 148.978 114.534 1.00 24.98  ? 356 ILE A C   1 
ATOM   2305 O  O   . ILE A 1 356 ? 127.275 149.068 114.389 1.00 24.98  ? 356 ILE A O   1 
ATOM   2306 C  CB  . ILE A 1 356 ? 124.799 150.653 115.970 1.00 24.98  ? 356 ILE A CB  1 
ATOM   2307 C  CG1 . ILE A 1 356 ? 124.308 152.100 115.984 1.00 24.98  ? 356 ILE A CG1 1 
ATOM   2308 C  CG2 . ILE A 1 356 ? 125.989 150.502 116.897 1.00 24.98  ? 356 ILE A CG2 1 
ATOM   2309 C  CD1 . ILE A 1 356 ? 123.892 152.590 117.352 1.00 24.98  ? 356 ILE A CD1 1 
ATOM   2310 N  N   . MET A 1 357 ? 125.440 147.800 114.694 1.00 28.05  ? 357 MET A N   1 
ATOM   2311 C  CA  . MET A 1 357 ? 126.190 146.551 114.599 1.00 28.05  ? 357 MET A CA  1 
ATOM   2312 C  C   . MET A 1 357 ? 126.931 146.460 113.274 1.00 28.05  ? 357 MET A C   1 
ATOM   2313 O  O   . MET A 1 357 ? 128.143 146.220 113.241 1.00 28.05  ? 357 MET A O   1 
ATOM   2314 C  CB  . MET A 1 357 ? 125.252 145.351 114.748 1.00 28.05  ? 357 MET A CB  1 
ATOM   2315 C  CG  . MET A 1 357 ? 125.864 144.153 115.457 1.00 28.05  ? 357 MET A CG  1 
ATOM   2316 S  SD  . MET A 1 357 ? 124.802 142.692 115.413 1.00 28.05  ? 357 MET A SD  1 
ATOM   2317 C  CE  . MET A 1 357 ? 123.835 142.882 116.904 1.00 28.05  ? 357 MET A CE  1 
ATOM   2318 N  N   . ALA A 1 358 ? 126.213 146.656 112.166 1.00 32.09  ? 358 ALA A N   1 
ATOM   2319 C  CA  . ALA A 1 358 ? 126.841 146.531 110.854 1.00 32.09  ? 358 ALA A CA  1 
ATOM   2320 C  C   . ALA A 1 358 ? 127.937 147.574 110.661 1.00 32.09  ? 358 ALA A C   1 
ATOM   2321 O  O   . ALA A 1 358 ? 129.026 147.259 110.158 1.00 32.09  ? 358 ALA A O   1 
ATOM   2322 C  CB  . ALA A 1 358 ? 125.788 146.648 109.754 1.00 32.09  ? 358 ALA A CB  1 
ATOM   2323 N  N   . LEU A 1 359 ? 127.667 148.819 111.062 1.00 35.27  ? 359 LEU A N   1 
ATOM   2324 C  CA  . LEU A 1 359 ? 128.634 149.897 110.900 1.00 35.27  ? 359 LEU A CA  1 
ATOM   2325 C  C   . LEU A 1 359 ? 129.914 149.597 111.661 1.00 35.27  ? 359 LEU A C   1 
ATOM   2326 O  O   . LEU A 1 359 ? 131.016 149.751 111.127 1.00 35.27  ? 359 LEU A O   1 
ATOM   2327 C  CB  . LEU A 1 359 ? 128.014 151.214 111.371 1.00 35.27  ? 359 LEU A CB  1 
ATOM   2328 C  CG  . LEU A 1 359 ? 128.797 152.514 111.185 1.00 35.27  ? 359 LEU A CG  1 
ATOM   2329 C  CD1 . LEU A 1 359 ? 127.858 153.633 110.777 1.00 35.27  ? 359 LEU A CD1 1 
ATOM   2330 C  CD2 . LEU A 1 359 ? 129.534 152.883 112.463 1.00 35.27  ? 359 LEU A CD2 1 
ATOM   2331 N  N   . LEU A 1 360 ? 129.789 149.149 112.911 1.00 34.23  ? 360 LEU A N   1 
ATOM   2332 C  CA  . LEU A 1 360 ? 130.977 148.772 113.666 1.00 34.23  ? 360 LEU A CA  1 
ATOM   2333 C  C   . LEU A 1 360 ? 131.668 147.565 113.049 1.00 34.23  ? 360 LEU A C   1 
ATOM   2334 O  O   . LEU A 1 360 ? 132.899 147.475 113.091 1.00 34.23  ? 360 LEU A O   1 
ATOM   2335 C  CB  . LEU A 1 360 ? 130.614 148.496 115.123 1.00 34.23  ? 360 LEU A CB  1 
ATOM   2336 C  CG  . LEU A 1 360 ? 130.671 149.674 116.098 1.00 34.23  ? 360 LEU A CG  1 
ATOM   2337 C  CD1 . LEU A 1 360 ? 132.095 150.188 116.212 1.00 34.23  ? 360 LEU A CD1 1 
ATOM   2338 C  CD2 . LEU A 1 360 ? 129.728 150.795 115.692 1.00 34.23  ? 360 LEU A CD2 1 
ATOM   2339 N  N   . TRP A 1 361 ? 130.906 146.642 112.461 1.00 34.07  ? 361 TRP A N   1 
ATOM   2340 C  CA  . TRP A 1 361 ? 131.513 145.453 111.873 1.00 34.07  ? 361 TRP A CA  1 
ATOM   2341 C  C   . TRP A 1 361 ? 132.407 145.807 110.693 1.00 34.07  ? 361 TRP A C   1 
ATOM   2342 O  O   . TRP A 1 361 ? 133.514 145.273 110.565 1.00 34.07  ? 361 TRP A O   1 
ATOM   2343 C  CB  . TRP A 1 361 ? 130.432 144.460 111.455 1.00 34.07  ? 361 TRP A CB  1 
ATOM   2344 C  CG  . TRP A 1 361 ? 129.936 143.639 112.591 1.00 34.07  ? 361 TRP A CG  1 
ATOM   2345 C  CD1 . TRP A 1 361 ? 129.948 143.977 113.910 1.00 34.07  ? 361 TRP A CD1 1 
ATOM   2346 C  CD2 . TRP A 1 361 ? 129.342 142.342 112.516 1.00 34.07  ? 361 TRP A CD2 1 
ATOM   2347 N  NE1 . TRP A 1 361 ? 129.402 142.970 114.663 1.00 34.07  ? 361 TRP A NE1 1 
ATOM   2348 C  CE2 . TRP A 1 361 ? 129.020 141.954 113.828 1.00 34.07  ? 361 TRP A CE2 1 
ATOM   2349 C  CE3 . TRP A 1 361 ? 129.050 141.472 111.465 1.00 34.07  ? 361 TRP A CE3 1 
ATOM   2350 C  CZ2 . TRP A 1 361 ? 128.422 140.735 114.118 1.00 34.07  ? 361 TRP A CZ2 1 
ATOM   2351 C  CZ3 . TRP A 1 361 ? 128.460 140.262 111.756 1.00 34.07  ? 361 TRP A CZ3 1 
ATOM   2352 C  CH2 . TRP A 1 361 ? 128.150 139.904 113.069 1.00 34.07  ? 361 TRP A CH2 1 
ATOM   2353 N  N   . PHE A 1 362 ? 131.951 146.698 109.811 1.00 45.23  ? 362 PHE A N   1 
ATOM   2354 C  CA  . PHE A 1 362 ? 132.832 147.049 108.697 1.00 45.23  ? 362 PHE A CA  1 
ATOM   2355 C  C   . PHE A 1 362 ? 133.622 148.333 108.935 1.00 45.23  ? 362 PHE A C   1 
ATOM   2356 O  O   . PHE A 1 362 ? 134.285 148.809 108.008 1.00 45.23  ? 362 PHE A O   1 
ATOM   2357 C  CB  . PHE A 1 362 ? 132.085 147.147 107.350 1.00 45.23  ? 362 PHE A CB  1 
ATOM   2358 C  CG  . PHE A 1 362 ? 131.088 148.268 107.250 1.00 45.23  ? 362 PHE A CG  1 
ATOM   2359 C  CD1 . PHE A 1 362 ? 131.477 149.517 106.791 1.00 45.23  ? 362 PHE A CD1 1 
ATOM   2360 C  CD2 . PHE A 1 362 ? 129.764 148.072 107.579 1.00 45.23  ? 362 PHE A CD2 1 
ATOM   2361 C  CE1 . PHE A 1 362 ? 130.566 150.551 106.687 1.00 45.23  ? 362 PHE A CE1 1 
ATOM   2362 C  CE2 . PHE A 1 362 ? 128.845 149.100 107.475 1.00 45.23  ? 362 PHE A CE2 1 
ATOM   2363 C  CZ  . PHE A 1 362 ? 129.247 150.342 107.029 1.00 45.23  ? 362 PHE A CZ  1 
ATOM   2364 N  N   . SER A 1 363 ? 133.574 148.905 110.138 1.00 45.15  ? 363 SER A N   1 
ATOM   2365 C  CA  . SER A 1 363 ? 134.411 150.049 110.480 1.00 45.15  ? 363 SER A CA  1 
ATOM   2366 C  C   . SER A 1 363 ? 135.560 149.685 111.413 1.00 45.15  ? 363 SER A C   1 
ATOM   2367 O  O   . SER A 1 363 ? 136.717 150.000 111.121 1.00 45.15  ? 363 SER A O   1 
ATOM   2368 C  CB  . SER A 1 363 ? 133.557 151.150 111.117 1.00 45.15  ? 363 SER A CB  1 
ATOM   2369 O  OG  . SER A 1 363 ? 134.367 152.205 111.604 1.00 45.15  ? 363 SER A OG  1 
ATOM   2370 N  N   . ARG A 1 364 ? 135.260 149.037 112.542 1.00 49.79  ? 364 ARG A N   1 
ATOM   2371 C  CA  . ARG A 1 364 ? 136.303 148.687 113.500 1.00 49.79  ? 364 ARG A CA  1 
ATOM   2372 C  C   . ARG A 1 364 ? 137.311 147.722 112.890 1.00 49.79  ? 364 ARG A C   1 
ATOM   2373 O  O   . ARG A 1 364 ? 138.522 147.862 113.099 1.00 49.79  ? 364 ARG A O   1 
ATOM   2374 C  CB  . ARG A 1 364 ? 135.674 148.087 114.759 1.00 49.79  ? 364 ARG A CB  1 
ATOM   2375 C  CG  . ARG A 1 364 ? 136.528 148.216 116.007 1.00 49.79  ? 364 ARG A CG  1 
ATOM   2376 C  CD  . ARG A 1 364 ? 135.679 148.194 117.268 1.00 49.79  ? 364 ARG A CD  1 
ATOM   2377 N  NE  . ARG A 1 364 ? 135.294 149.537 117.690 1.00 49.79  ? 364 ARG A NE  1 
ATOM   2378 C  CZ  . ARG A 1 364 ? 134.607 149.810 118.791 1.00 49.79  ? 364 ARG A CZ  1 
ATOM   2379 N  NH1 . ARG A 1 364 ? 134.210 148.854 119.614 1.00 49.79  ? 364 ARG A NH1 1 
ATOM   2380 N  NH2 . ARG A 1 364 ? 134.310 151.076 119.072 1.00 49.79  ? 364 ARG A NH2 1 
ATOM   2381 N  N   . ASP A 1 365 ? 136.833 146.741 112.126 1.00 50.40  ? 365 ASP A N   1 
ATOM   2382 C  CA  . ASP A 1 365 ? 137.705 145.787 111.449 1.00 50.40  ? 365 ASP A CA  1 
ATOM   2383 C  C   . ASP A 1 365 ? 137.559 145.954 109.942 1.00 50.40  ? 365 ASP A C   1 
ATOM   2384 O  O   . ASP A 1 365 ? 136.610 145.420 109.348 1.00 50.40  ? 365 ASP A O   1 
ATOM   2385 C  CB  . ASP A 1 365 ? 137.364 144.354 111.866 1.00 50.40  ? 365 ASP A CB  1 
ATOM   2386 C  CG  . ASP A 1 365 ? 137.656 144.088 113.329 1.00 50.40  ? 365 ASP A CG  1 
ATOM   2387 O  OD1 . ASP A 1 365 ? 138.551 144.753 113.887 1.00 50.40  ? 365 ASP A OD1 1 
ATOM   2388 O  OD2 . ASP A 1 365 ? 136.991 143.212 113.920 1.00 50.40  ? 365 ASP A OD2 1 
ATOM   2389 N  N   . PRO A 1 366 ? 138.467 146.681 109.273 1.00 56.65  ? 366 PRO A N   1 
ATOM   2390 C  CA  . PRO A 1 366 ? 138.391 146.912 107.830 1.00 56.65  ? 366 PRO A CA  1 
ATOM   2391 C  C   . PRO A 1 366 ? 139.189 145.892 107.026 1.00 56.65  ? 366 PRO A C   1 
ATOM   2392 O  O   . PRO A 1 366 ? 139.734 146.253 105.984 1.00 56.65  ? 366 PRO A O   1 
ATOM   2393 C  CB  . PRO A 1 366 ? 138.988 148.313 107.675 1.00 56.65  ? 366 PRO A CB  1 
ATOM   2394 C  CG  . PRO A 1 366 ? 139.891 148.494 108.884 1.00 56.65  ? 366 PRO A CG  1 
ATOM   2395 C  CD  . PRO A 1 366 ? 139.611 147.386 109.874 1.00 56.65  ? 366 PRO A CD  1 
ATOM   2396 N  N   . SER A 1 373 ? 139.771 147.746 115.514 1.00 55.21  ? 373 SER A N   1 
ATOM   2397 C  CA  . SER A 1 373 ? 141.203 148.001 115.572 1.00 55.21  ? 373 SER A CA  1 
ATOM   2398 C  C   . SER A 1 373 ? 141.486 149.497 115.566 1.00 55.21  ? 373 SER A C   1 
ATOM   2399 O  O   . SER A 1 373 ? 140.562 150.308 115.649 1.00 55.21  ? 373 SER A O   1 
ATOM   2400 C  CB  . SER A 1 373 ? 141.918 147.322 114.404 1.00 55.21  ? 373 SER A CB  1 
ATOM   2401 O  OG  . SER A 1 373 ? 141.541 145.961 114.298 1.00 55.21  ? 373 SER A OG  1 
ATOM   2402 N  N   . ALA A 1 374 ? 142.776 149.842 115.503 1.00 63.96  ? 374 ALA A N   1 
ATOM   2403 C  CA  . ALA A 1 374 ? 143.261 151.220 115.444 1.00 63.96  ? 374 ALA A CA  1 
ATOM   2404 C  C   . ALA A 1 374 ? 142.996 151.966 116.746 1.00 63.96  ? 374 ALA A C   1 
ATOM   2405 O  O   . ALA A 1 374 ? 143.406 153.121 116.902 1.00 63.96  ? 374 ALA A O   1 
ATOM   2406 C  CB  . ALA A 1 374 ? 142.640 151.971 114.261 1.00 63.96  ? 374 ALA A CB  1 
ATOM   2407 N  N   . LEU A 1 375 ? 142.314 151.313 117.688 1.00 60.55  ? 375 LEU A N   1 
ATOM   2408 C  CA  . LEU A 1 375 ? 142.099 151.852 119.022 1.00 60.55  ? 375 LEU A CA  1 
ATOM   2409 C  C   . LEU A 1 375 ? 142.670 150.965 120.114 1.00 60.55  ? 375 LEU A C   1 
ATOM   2410 O  O   . LEU A 1 375 ? 143.041 151.478 121.174 1.00 60.55  ? 375 LEU A O   1 
ATOM   2411 C  CB  . LEU A 1 375 ? 140.600 152.064 119.289 1.00 60.55  ? 375 LEU A CB  1 
ATOM   2412 C  CG  . LEU A 1 375 ? 139.900 153.281 118.676 1.00 60.55  ? 375 LEU A CG  1 
ATOM   2413 C  CD1 . LEU A 1 375 ? 139.725 153.145 117.169 1.00 60.55  ? 375 LEU A CD1 1 
ATOM   2414 C  CD2 . LEU A 1 375 ? 138.557 153.513 119.351 1.00 60.55  ? 375 LEU A CD2 1 
ATOM   2415 N  N   . PHE A 1 376 ? 142.746 149.657 119.882 1.00 56.39  ? 376 PHE A N   1 
ATOM   2416 C  CA  . PHE A 1 376 ? 143.389 148.704 120.781 1.00 56.39  ? 376 PHE A CA  1 
ATOM   2417 C  C   . PHE A 1 376 ? 144.576 148.128 120.015 1.00 56.39  ? 376 PHE A C   1 
ATOM   2418 O  O   . PHE A 1 376 ? 144.469 147.076 119.382 1.00 56.39  ? 376 PHE A O   1 
ATOM   2419 C  CB  . PHE A 1 376 ? 142.422 147.611 121.222 1.00 56.39  ? 376 PHE A CB  1 
ATOM   2420 C  CG  . PHE A 1 376 ? 141.030 148.102 121.491 1.00 56.39  ? 376 PHE A CG  1 
ATOM   2421 C  CD1 . PHE A 1 376 ? 140.728 148.759 122.671 1.00 56.39  ? 376 PHE A CD1 1 
ATOM   2422 C  CD2 . PHE A 1 376 ? 140.021 147.898 120.568 1.00 56.39  ? 376 PHE A CD2 1 
ATOM   2423 C  CE1 . PHE A 1 376 ? 139.447 149.208 122.922 1.00 56.39  ? 376 PHE A CE1 1 
ATOM   2424 C  CE2 . PHE A 1 376 ? 138.738 148.344 120.813 1.00 56.39  ? 376 PHE A CE2 1 
ATOM   2425 C  CZ  . PHE A 1 376 ? 138.451 149.000 121.991 1.00 56.39  ? 376 PHE A CZ  1 
ATOM   2426 N  N   . SER A 1 377 ? 145.709 148.824 120.072 1.00 54.00  ? 377 SER A N   1 
ATOM   2427 C  CA  . SER A 1 377 ? 146.901 148.431 119.330 1.00 54.00  ? 377 SER A CA  1 
ATOM   2428 C  C   . SER A 1 377 ? 147.812 147.501 120.116 1.00 54.00  ? 377 SER A C   1 
ATOM   2429 O  O   . SER A 1 377 ? 148.398 146.583 119.535 1.00 54.00  ? 377 SER A O   1 
ATOM   2430 C  CB  . SER A 1 377 ? 147.689 149.672 118.902 1.00 54.00  ? 377 SER A CB  1 
ATOM   2431 O  OG  . SER A 1 377 ? 146.878 150.555 118.147 1.00 54.00  ? 377 SER A OG  1 
ATOM   2432 N  N   . GLU A 1 378 ? 147.945 147.715 121.426 1.00 49.94  ? 378 GLU A N   1 
ATOM   2433 C  CA  . GLU A 1 378 ? 148.792 146.851 122.239 1.00 49.94  ? 378 GLU A CA  1 
ATOM   2434 C  C   . GLU A 1 378 ? 148.240 145.435 122.331 1.00 49.94  ? 378 GLU A C   1 
ATOM   2435 O  O   . GLU A 1 378 ? 148.992 144.505 122.643 1.00 49.94  ? 378 GLU A O   1 
ATOM   2436 C  CB  . GLU A 1 378 ? 148.958 147.450 123.638 1.00 49.94  ? 378 GLU A CB  1 
ATOM   2437 C  CG  . GLU A 1 378 ? 150.020 146.774 124.492 1.00 49.94  ? 378 GLU A CG  1 
ATOM   2438 C  CD  . GLU A 1 378 ? 150.101 147.351 125.891 1.00 49.94  ? 378 GLU A CD  1 
ATOM   2439 O  OE1 . GLU A 1 378 ? 149.483 148.408 126.138 1.00 49.94  ? 378 GLU A OE1 1 
ATOM   2440 O  OE2 . GLU A 1 378 ? 150.782 146.746 126.745 1.00 49.94  ? 378 GLU A OE2 1 
ATOM   2441 N  N   . TYR A 1 379 ? 146.951 145.247 122.049 1.00 40.33  ? 379 TYR A N   1 
ATOM   2442 C  CA  . TYR A 1 379 ? 146.301 143.938 122.096 1.00 40.33  ? 379 TYR A CA  1 
ATOM   2443 C  C   . TYR A 1 379 ? 145.648 143.680 120.745 1.00 40.33  ? 379 TYR A C   1 
ATOM   2444 O  O   . TYR A 1 379 ? 144.441 143.915 120.573 1.00 40.33  ? 379 TYR A O   1 
ATOM   2445 C  CB  . TYR A 1 379 ? 145.275 143.875 123.224 1.00 40.33  ? 379 TYR A CB  1 
ATOM   2446 C  CG  . TYR A 1 379 ? 145.679 144.641 124.462 1.00 40.33  ? 379 TYR A CG  1 
ATOM   2447 C  CD1 . TYR A 1 379 ? 146.724 144.202 125.263 1.00 40.33  ? 379 TYR A CD1 1 
ATOM   2448 C  CD2 . TYR A 1 379 ? 145.017 145.804 124.828 1.00 40.33  ? 379 TYR A CD2 1 
ATOM   2449 C  CE1 . TYR A 1 379 ? 147.096 144.899 126.395 1.00 40.33  ? 379 TYR A CE1 1 
ATOM   2450 C  CE2 . TYR A 1 379 ? 145.383 146.508 125.957 1.00 40.33  ? 379 TYR A CE2 1 
ATOM   2451 C  CZ  . TYR A 1 379 ? 146.423 146.051 126.737 1.00 40.33  ? 379 TYR A CZ  1 
ATOM   2452 O  OH  . TYR A 1 379 ? 146.790 146.750 127.863 1.00 40.33  ? 379 TYR A OH  1 
ATOM   2453 N  N   . PRO A 1 380 ? 146.403 143.198 119.758 1.00 36.83  ? 380 PRO A N   1 
ATOM   2454 C  CA  . PRO A 1 380 ? 145.815 142.946 118.437 1.00 36.83  ? 380 PRO A CA  1 
ATOM   2455 C  C   . PRO A 1 380 ? 145.154 141.581 118.351 1.00 36.83  ? 380 PRO A C   1 
ATOM   2456 O  O   . PRO A 1 380 ? 145.742 140.570 118.746 1.00 36.83  ? 380 PRO A O   1 
ATOM   2457 C  CB  . PRO A 1 380 ? 147.018 143.051 117.488 1.00 36.83  ? 380 PRO A CB  1 
ATOM   2458 C  CG  . PRO A 1 380 ? 148.256 143.028 118.371 1.00 36.83  ? 380 PRO A CG  1 
ATOM   2459 C  CD  . PRO A 1 380 ? 147.831 142.853 119.797 1.00 36.83  ? 380 PRO A CD  1 
ATOM   2460 N  N   . GLY A 1 381 ? 143.928 141.545 117.833 1.00 31.09  ? 381 GLY A N   1 
ATOM   2461 C  CA  . GLY A 1 381 ? 143.177 140.315 117.720 1.00 31.09  ? 381 GLY A CA  1 
ATOM   2462 C  C   . GLY A 1 381 ? 142.400 139.923 118.955 1.00 31.09  ? 381 GLY A C   1 
ATOM   2463 O  O   . GLY A 1 381 ? 141.693 138.907 118.925 1.00 31.09  ? 381 GLY A O   1 
ATOM   2464 N  N   . PHE A 1 382 ? 142.509 140.688 120.043 1.00 26.77  ? 382 PHE A N   1 
ATOM   2465 C  CA  . PHE A 1 382 ? 141.769 140.355 121.255 1.00 26.77  ? 382 PHE A CA  1 
ATOM   2466 C  C   . PHE A 1 382 ? 140.275 140.592 121.075 1.00 26.77  ? 382 PHE A C   1 
ATOM   2467 O  O   . PHE A 1 382 ? 139.458 139.746 121.454 1.00 26.77  ? 382 PHE A O   1 
ATOM   2468 C  CB  . PHE A 1 382 ? 142.306 141.162 122.435 1.00 26.77  ? 382 PHE A CB  1 
ATOM   2469 C  CG  . PHE A 1 382 ? 143.556 140.591 123.042 1.00 26.77  ? 382 PHE A CG  1 
ATOM   2470 C  CD1 . PHE A 1 382 ? 144.678 140.360 122.267 1.00 26.77  ? 382 PHE A CD1 1 
ATOM   2471 C  CD2 . PHE A 1 382 ? 143.610 140.288 124.389 1.00 26.77  ? 382 PHE A CD2 1 
ATOM   2472 C  CE1 . PHE A 1 382 ? 145.825 139.837 122.822 1.00 26.77  ? 382 PHE A CE1 1 
ATOM   2473 C  CE2 . PHE A 1 382 ? 144.756 139.765 124.948 1.00 26.77  ? 382 PHE A CE2 1 
ATOM   2474 C  CZ  . PHE A 1 382 ? 145.863 139.539 124.164 1.00 26.77  ? 382 PHE A CZ  1 
ATOM   2475 N  N   . ALA A 1 383 ? 139.900 141.727 120.495 1.00 24.34  ? 383 ALA A N   1 
ATOM   2476 C  CA  . ALA A 1 383 ? 138.504 142.062 120.255 1.00 24.34  ? 383 ALA A CA  1 
ATOM   2477 C  C   . ALA A 1 383 ? 138.162 141.784 118.798 1.00 24.34  ? 383 ALA A C   1 
ATOM   2478 O  O   . ALA A 1 383 ? 138.850 142.264 117.892 1.00 24.34  ? 383 ALA A O   1 
ATOM   2479 C  CB  . ALA A 1 383 ? 138.225 143.526 120.597 1.00 24.34  ? 383 ALA A CB  1 
ATOM   2480 N  N   . THR A 1 384 ? 137.100 141.012 118.577 1.00 23.94  ? 384 THR A N   1 
ATOM   2481 C  CA  . THR A 1 384 ? 136.717 140.609 117.230 1.00 23.94  ? 384 THR A CA  1 
ATOM   2482 C  C   . THR A 1 384 ? 135.269 140.979 116.942 1.00 23.94  ? 384 THR A C   1 
ATOM   2483 O  O   . THR A 1 384 ? 134.645 141.715 117.712 1.00 23.94  ? 384 THR A O   1 
ATOM   2484 C  CB  . THR A 1 384 ? 136.921 139.105 117.039 1.00 23.94  ? 384 THR A CB  1 
ATOM   2485 O  OG1 . THR A 1 384 ? 136.176 138.391 118.032 1.00 23.94  ? 384 THR A OG1 1 
ATOM   2486 C  CG2 . THR A 1 384 ? 138.394 138.745 117.164 1.00 23.94  ? 384 THR A CG2 1 
ATOM   2487 N  N   . ASP A 1 385 ? 134.731 140.480 115.825 1.00 27.41  ? 385 ASP A N   1 
ATOM   2488 C  CA  . ASP A 1 385 ? 133.346 140.773 115.471 1.00 27.41  ? 385 ASP A CA  1 
ATOM   2489 C  C   . ASP A 1 385 ? 132.372 140.225 116.504 1.00 27.41  ? 385 ASP A C   1 
ATOM   2490 O  O   . ASP A 1 385 ? 131.287 140.786 116.692 1.00 27.41  ? 385 ASP A O   1 
ATOM   2491 C  CB  . ASP A 1 385 ? 133.026 140.203 114.091 1.00 27.41  ? 385 ASP A CB  1 
ATOM   2492 C  CG  . ASP A 1 385 ? 134.020 140.638 113.038 1.00 27.41  ? 385 ASP A CG  1 
ATOM   2493 O  OD1 . ASP A 1 385 ? 134.527 141.775 113.133 1.00 27.41  ? 385 ASP A OD1 1 
ATOM   2494 O  OD2 . ASP A 1 385 ? 134.299 139.844 112.117 1.00 27.41  ? 385 ASP A OD2 1 
ATOM   2495 N  N   . SER A 1 386 ? 132.736 139.132 117.178 1.00 20.79  ? 386 SER A N   1 
ATOM   2496 C  CA  . SER A 1 386 ? 131.876 138.595 118.225 1.00 20.79  ? 386 SER A CA  1 
ATOM   2497 C  C   . SER A 1 386 ? 131.750 139.559 119.393 1.00 20.79  ? 386 SER A C   1 
ATOM   2498 O  O   . SER A 1 386 ? 130.689 139.630 120.020 1.00 20.79  ? 386 SER A O   1 
ATOM   2499 C  CB  . SER A 1 386 ? 132.408 137.251 118.710 1.00 20.79  ? 386 SER A CB  1 
ATOM   2500 O  OG  . SER A 1 386 ? 133.642 137.415 119.382 1.00 20.79  ? 386 SER A OG  1 
ATOM   2501 N  N   . THR A 1 387 ? 132.815 140.300 119.704 1.00 18.56  ? 387 THR A N   1 
ATOM   2502 C  CA  . THR A 1 387 ? 132.730 141.297 120.765 1.00 18.56  ? 387 THR A CA  1 
ATOM   2503 C  C   . THR A 1 387 ? 131.720 142.382 120.418 1.00 18.56  ? 387 THR A C   1 
ATOM   2504 O  O   . THR A 1 387 ? 130.914 142.780 121.264 1.00 18.56  ? 387 THR A O   1 
ATOM   2505 C  CB  . THR A 1 387 ? 134.107 141.905 121.026 1.00 18.56  ? 387 THR A CB  1 
ATOM   2506 O  OG1 . THR A 1 387 ? 135.030 140.864 121.367 1.00 18.56  ? 387 THR A OG1 1 
ATOM   2507 C  CG2 . THR A 1 387 ? 134.040 142.903 122.165 1.00 18.56  ? 387 THR A CG2 1 
ATOM   2508 N  N   . VAL A 1 388 ? 131.735 142.862 119.174 1.00 18.82  ? 388 VAL A N   1 
ATOM   2509 C  CA  . VAL A 1 388 ? 130.759 143.862 118.751 1.00 18.82  ? 388 VAL A CA  1 
ATOM   2510 C  C   . VAL A 1 388 ? 129.352 143.278 118.765 1.00 18.82  ? 388 VAL A C   1 
ATOM   2511 O  O   . VAL A 1 388 ? 128.388 143.944 119.171 1.00 18.82  ? 388 VAL A O   1 
ATOM   2512 C  CB  . VAL A 1 388 ? 131.124 144.410 117.361 1.00 18.82  ? 388 VAL A CB  1 
ATOM   2513 C  CG1 . VAL A 1 388 ? 130.162 145.508 116.971 1.00 18.82  ? 388 VAL A CG1 1 
ATOM   2514 C  CG2 . VAL A 1 388 ? 132.556 144.913 117.348 1.00 18.82  ? 388 VAL A CG2 1 
ATOM   2515 N  N   . ALA A 1 389 ? 129.209 142.032 118.307 1.00 17.98  ? 389 ALA A N   1 
ATOM   2516 C  CA  . ALA A 1 389 ? 127.901 141.389 118.303 1.00 17.98  ? 389 ALA A CA  1 
ATOM   2517 C  C   . ALA A 1 389 ? 127.341 141.287 119.713 1.00 17.98  ? 389 ALA A C   1 
ATOM   2518 O  O   . ALA A 1 389 ? 126.172 141.601 119.950 1.00 17.98  ? 389 ALA A O   1 
ATOM   2519 C  CB  . ALA A 1 389 ? 127.999 140.007 117.660 1.00 17.98  ? 389 ALA A CB  1 
ATOM   2520 N  N   . LEU A 1 390 ? 128.172 140.866 120.669 1.00 14.48  ? 390 LEU A N   1 
ATOM   2521 C  CA  . LEU A 1 390 ? 127.736 140.800 122.060 1.00 14.48  ? 390 LEU A CA  1 
ATOM   2522 C  C   . LEU A 1 390 ? 127.420 142.184 122.607 1.00 14.48  ? 390 LEU A C   1 
ATOM   2523 O  O   . LEU A 1 390 ? 126.429 142.363 123.323 1.00 14.48  ? 390 LEU A O   1 
ATOM   2524 C  CB  . LEU A 1 390 ? 128.807 140.127 122.915 1.00 14.48  ? 390 LEU A CB  1 
ATOM   2525 C  CG  . LEU A 1 390 ? 128.884 138.606 122.838 1.00 14.48  ? 390 LEU A CG  1 
ATOM   2526 C  CD1 . LEU A 1 390 ? 130.136 138.124 123.529 1.00 14.48  ? 390 LEU A CD1 1 
ATOM   2527 C  CD2 . LEU A 1 390 ? 127.654 137.984 123.465 1.00 14.48  ? 390 LEU A CD2 1 
ATOM   2528 N  N   . LEU A 1 391 ? 128.250 143.176 122.279 1.00 14.29  ? 391 LEU A N   1 
ATOM   2529 C  CA  . LEU A 1 391 ? 128.036 144.523 122.791 1.00 14.29  ? 391 LEU A CA  1 
ATOM   2530 C  C   . LEU A 1 391 ? 126.684 145.064 122.358 1.00 14.29  ? 391 LEU A C   1 
ATOM   2531 O  O   . LEU A 1 391 ? 125.964 145.671 123.157 1.00 14.29  ? 391 LEU A O   1 
ATOM   2532 C  CB  . LEU A 1 391 ? 129.157 145.444 122.310 1.00 14.29  ? 391 LEU A CB  1 
ATOM   2533 C  CG  . LEU A 1 391 ? 129.197 146.873 122.850 1.00 14.29  ? 391 LEU A CG  1 
ATOM   2534 C  CD1 . LEU A 1 391 ? 128.888 146.903 124.335 1.00 14.29  ? 391 LEU A CD1 1 
ATOM   2535 C  CD2 . LEU A 1 391 ? 130.552 147.494 122.570 1.00 14.29  ? 391 LEU A CD2 1 
ATOM   2536 N  N   . ILE A 1 392 ? 126.323 144.857 121.092 1.00 17.66  ? 392 ILE A N   1 
ATOM   2537 C  CA  . ILE A 1 392 ? 125.035 145.350 120.618 1.00 17.66  ? 392 ILE A CA  1 
ATOM   2538 C  C   . ILE A 1 392 ? 123.895 144.477 121.133 1.00 17.66  ? 392 ILE A C   1 
ATOM   2539 O  O   . ILE A 1 392 ? 122.832 144.984 121.507 1.00 17.66  ? 392 ILE A O   1 
ATOM   2540 C  CB  . ILE A 1 392 ? 125.035 145.455 119.085 1.00 17.66  ? 392 ILE A CB  1 
ATOM   2541 C  CG1 . ILE A 1 392 ? 126.197 146.333 118.627 1.00 17.66  ? 392 ILE A CG1 1 
ATOM   2542 C  CG2 . ILE A 1 392 ? 123.723 146.039 118.598 1.00 17.66  ? 392 ILE A CG2 1 
ATOM   2543 C  CD1 . ILE A 1 392 ? 126.186 147.714 119.237 1.00 17.66  ? 392 ILE A CD1 1 
ATOM   2544 N  N   . GLY A 1 393 ? 124.091 143.156 121.163 1.00 13.57  ? 393 GLY A N   1 
ATOM   2545 C  CA  . GLY A 1 393 ? 123.013 142.262 121.551 1.00 13.57  ? 393 GLY A CA  1 
ATOM   2546 C  C   . GLY A 1 393 ? 122.617 142.391 123.009 1.00 13.57  ? 393 GLY A C   1 
ATOM   2547 O  O   . GLY A 1 393 ? 121.430 142.359 123.340 1.00 13.57  ? 393 GLY A O   1 
ATOM   2548 N  N   . LEU A 1 394 ? 123.599 142.529 123.902 1.00 13.07  ? 394 LEU A N   1 
ATOM   2549 C  CA  . LEU A 1 394 ? 123.297 142.688 125.318 1.00 13.07  ? 394 LEU A CA  1 
ATOM   2550 C  C   . LEU A 1 394 ? 122.546 143.976 125.613 1.00 13.07  ? 394 LEU A C   1 
ATOM   2551 O  O   . LEU A 1 394 ? 121.921 144.078 126.673 1.00 13.07  ? 394 LEU A O   1 
ATOM   2552 C  CB  . LEU A 1 394 ? 124.585 142.640 126.141 1.00 13.07  ? 394 LEU A CB  1 
ATOM   2553 C  CG  . LEU A 1 394 ? 125.325 141.301 126.182 1.00 13.07  ? 394 LEU A CG  1 
ATOM   2554 C  CD1 . LEU A 1 394 ? 126.398 141.316 127.254 1.00 13.07  ? 394 LEU A CD1 1 
ATOM   2555 C  CD2 . LEU A 1 394 ? 124.360 140.150 126.401 1.00 13.07  ? 394 LEU A CD2 1 
ATOM   2556 N  N   . LEU A 1 395 ? 122.593 144.957 124.711 1.00 13.86  ? 395 LEU A N   1 
ATOM   2557 C  CA  . LEU A 1 395 ? 121.777 146.154 124.851 1.00 13.86  ? 395 LEU A CA  1 
ATOM   2558 C  C   . LEU A 1 395 ? 120.299 145.874 124.632 1.00 13.86  ? 395 LEU A C   1 
ATOM   2559 O  O   . LEU A 1 395 ? 119.467 146.717 124.978 1.00 13.86  ? 395 LEU A O   1 
ATOM   2560 C  CB  . LEU A 1 395 ? 122.248 147.229 123.873 1.00 13.86  ? 395 LEU A CB  1 
ATOM   2561 C  CG  . LEU A 1 395 ? 123.619 147.837 124.159 1.00 13.86  ? 395 LEU A CG  1 
ATOM   2562 C  CD1 . LEU A 1 395 ? 123.967 148.874 123.109 1.00 13.86  ? 395 LEU A CD1 1 
ATOM   2563 C  CD2 . LEU A 1 395 ? 123.651 148.441 125.548 1.00 13.86  ? 395 LEU A CD2 1 
ATOM   2564 N  N   . PHE A 1 396 ? 119.957 144.719 124.068 1.00 14.76  ? 396 PHE A N   1 
ATOM   2565 C  CA  . PHE A 1 396 ? 118.572 144.294 123.939 1.00 14.76  ? 396 PHE A CA  1 
ATOM   2566 C  C   . PHE A 1 396 ? 118.033 143.667 125.214 1.00 14.76  ? 396 PHE A C   1 
ATOM   2567 O  O   . PHE A 1 396 ? 116.894 143.195 125.218 1.00 14.76  ? 396 PHE A O   1 
ATOM   2568 C  CB  . PHE A 1 396 ? 118.430 143.295 122.790 1.00 14.76  ? 396 PHE A CB  1 
ATOM   2569 C  CG  . PHE A 1 396 ? 118.486 143.917 121.428 1.00 14.76  ? 396 PHE A CG  1 
ATOM   2570 C  CD1 . PHE A 1 396 ? 117.462 144.731 120.982 1.00 14.76  ? 396 PHE A CD1 1 
ATOM   2571 C  CD2 . PHE A 1 396 ? 119.555 143.674 120.586 1.00 14.76  ? 396 PHE A CD2 1 
ATOM   2572 C  CE1 . PHE A 1 396 ? 117.508 145.298 119.729 1.00 14.76  ? 396 PHE A CE1 1 
ATOM   2573 C  CE2 . PHE A 1 396 ? 119.606 144.238 119.330 1.00 14.76  ? 396 PHE A CE2 1 
ATOM   2574 C  CZ  . PHE A 1 396 ? 118.580 145.049 118.901 1.00 14.76  ? 396 PHE A CZ  1 
ATOM   2575 N  N   . PHE A 1 397 ? 118.830 143.622 126.279 1.00 14.39  ? 397 PHE A N   1 
ATOM   2576 C  CA  . PHE A 1 397 ? 118.405 143.071 127.556 1.00 14.39  ? 397 PHE A CA  1 
ATOM   2577 C  C   . PHE A 1 397 ? 118.228 144.132 128.631 1.00 14.39  ? 397 PHE A C   1 
ATOM   2578 O  O   . PHE A 1 397 ? 117.855 143.793 129.758 1.00 14.39  ? 397 PHE A O   1 
ATOM   2579 C  CB  . PHE A 1 397 ? 119.410 142.020 128.041 1.00 14.39  ? 397 PHE A CB  1 
ATOM   2580 C  CG  . PHE A 1 397 ? 119.250 140.679 127.390 1.00 14.39  ? 397 PHE A CG  1 
ATOM   2581 C  CD1 . PHE A 1 397 ? 118.199 139.850 127.733 1.00 14.39  ? 397 PHE A CD1 1 
ATOM   2582 C  CD2 . PHE A 1 397 ? 120.160 140.241 126.447 1.00 14.39  ? 397 PHE A CD2 1 
ATOM   2583 C  CE1 . PHE A 1 397 ? 118.055 138.616 127.139 1.00 14.39  ? 397 PHE A CE1 1 
ATOM   2584 C  CE2 . PHE A 1 397 ? 120.020 139.007 125.852 1.00 14.39  ? 397 PHE A CE2 1 
ATOM   2585 C  CZ  . PHE A 1 397 ? 118.967 138.194 126.198 1.00 14.39  ? 397 PHE A CZ  1 
ATOM   2586 N  N   . LEU A 1 398 ? 118.495 145.400 128.324 1.00 17.70  ? 398 LEU A N   1 
ATOM   2587 C  CA  . LEU A 1 398 ? 118.337 146.472 129.298 1.00 17.70  ? 398 LEU A CA  1 
ATOM   2588 C  C   . LEU A 1 398 ? 117.612 147.703 128.775 1.00 17.70  ? 398 LEU A C   1 
ATOM   2589 O  O   . LEU A 1 398 ? 117.145 148.502 129.594 1.00 17.70  ? 398 LEU A O   1 
ATOM   2590 C  CB  . LEU A 1 398 ? 119.705 146.894 129.861 1.00 17.70  ? 398 LEU A CB  1 
ATOM   2591 C  CG  . LEU A 1 398 ? 120.823 147.342 128.918 1.00 17.70  ? 398 LEU A CG  1 
ATOM   2592 C  CD1 . LEU A 1 398 ? 120.760 148.830 128.628 1.00 17.70  ? 398 LEU A CD1 1 
ATOM   2593 C  CD2 . LEU A 1 398 ? 122.176 146.976 129.501 1.00 17.70  ? 398 LEU A CD2 1 
ATOM   2594 N  N   . ILE A 1 399 ? 117.501 147.891 127.467 1.00 18.74  ? 399 ILE A N   1 
ATOM   2595 C  CA  . ILE A 1 399 ? 116.791 149.068 126.952 1.00 18.74  ? 399 ILE A CA  1 
ATOM   2596 C  C   . ILE A 1 399 ? 115.295 148.889 127.182 1.00 18.74  ? 399 ILE A C   1 
ATOM   2597 O  O   . ILE A 1 399 ? 114.720 147.880 126.739 1.00 18.74  ? 399 ILE A O   1 
ATOM   2598 C  CB  . ILE A 1 399 ? 117.100 149.270 125.470 1.00 18.74  ? 399 ILE A CB  1 
ATOM   2599 C  CG1 . ILE A 1 399 ? 118.527 149.788 125.293 1.00 18.74  ? 399 ILE A CG1 1 
ATOM   2600 C  CG2 . ILE A 1 399 ? 116.113 150.242 124.851 1.00 18.74  ? 399 ILE A CG2 1 
ATOM   2601 C  CD1 . ILE A 1 399 ? 118.981 149.838 123.857 1.00 18.74  ? 399 ILE A CD1 1 
ATOM   2602 N  N   . PRO A 1 400 ? 114.627 149.820 127.861 1.00 24.42  ? 400 PRO A N   1 
ATOM   2603 C  CA  . PRO A 1 400 ? 113.208 149.629 128.178 1.00 24.42  ? 400 PRO A CA  1 
ATOM   2604 C  C   . PRO A 1 400 ? 112.333 149.583 126.935 1.00 24.42  ? 400 PRO A C   1 
ATOM   2605 O  O   . PRO A 1 400 ? 112.569 150.283 125.948 1.00 24.42  ? 400 PRO A O   1 
ATOM   2606 C  CB  . PRO A 1 400 ? 112.873 150.848 129.045 1.00 24.42  ? 400 PRO A CB  1 
ATOM   2607 C  CG  . PRO A 1 400 ? 113.896 151.863 128.684 1.00 24.42  ? 400 PRO A CG  1 
ATOM   2608 C  CD  . PRO A 1 400 ? 115.144 151.093 128.388 1.00 24.42  ? 400 PRO A CD  1 
ATOM   2609 N  N   . ALA A 1 401 ? 111.305 148.736 127.001 1.00 28.33  ? 401 ALA A N   1 
ATOM   2610 C  CA  . ALA A 1 401 ? 110.327 148.606 125.927 1.00 28.33  ? 401 ALA A CA  1 
ATOM   2611 C  C   . ALA A 1 401 ? 108.933 149.025 126.370 1.00 28.33  ? 401 ALA A C   1 
ATOM   2612 O  O   . ALA A 1 401 ? 108.318 149.879 125.725 1.00 28.33  ? 401 ALA A O   1 
ATOM   2613 C  CB  . ALA A 1 401 ? 110.305 147.166 125.402 1.00 28.33  ? 401 ALA A CB  1 
ATOM   2614 N  N   . LYS A 1 402 ? 108.415 148.450 127.450 1.00 38.21  ? 402 LYS A N   1 
ATOM   2615 C  CA  . LYS A 1 402 ? 107.054 148.706 127.891 1.00 38.21  ? 402 LYS A CA  1 
ATOM   2616 C  C   . LYS A 1 402 ? 107.038 148.988 129.386 1.00 38.21  ? 402 LYS A C   1 
ATOM   2617 O  O   . LYS A 1 402 ? 107.830 148.438 130.155 1.00 38.21  ? 402 LYS A O   1 
ATOM   2618 C  CB  . LYS A 1 402 ? 106.134 147.520 127.569 1.00 38.21  ? 402 LYS A CB  1 
ATOM   2619 C  CG  . LYS A 1 402 ? 104.653 147.846 127.614 1.00 38.21  ? 402 LYS A CG  1 
ATOM   2620 C  CD  . LYS A 1 402 ? 103.818 146.677 127.122 1.00 38.21  ? 402 LYS A CD  1 
ATOM   2621 C  CE  . LYS A 1 402 ? 104.029 146.435 125.635 1.00 38.21  ? 402 LYS A CE  1 
ATOM   2622 N  NZ  . LYS A 1 402 ? 103.960 147.697 124.848 1.00 38.21  ? 402 LYS A NZ  1 
ATOM   2623 N  N   . THR A 1 403 ? 106.120 149.862 129.788 1.00 46.27  ? 403 THR A N   1 
ATOM   2624 C  CA  . THR A 1 403 ? 105.919 150.174 131.192 1.00 46.27  ? 403 THR A CA  1 
ATOM   2625 C  C   . THR A 1 403 ? 105.168 149.030 131.874 1.00 46.27  ? 403 THR A C   1 
ATOM   2626 O  O   . THR A 1 403 ? 104.305 148.380 131.277 1.00 46.27  ? 403 THR A O   1 
ATOM   2627 C  CB  . THR A 1 403 ? 105.157 151.495 131.333 1.00 46.27  ? 403 THR A CB  1 
ATOM   2628 O  OG1 . THR A 1 403 ? 105.912 152.544 130.716 1.00 46.27  ? 403 THR A OG1 1 
ATOM   2629 C  CG2 . THR A 1 403 ? 104.954 151.853 132.791 1.00 46.27  ? 403 THR A CG2 1 
ATOM   2630 N  N   . LEU A 1 404 ? 105.520 148.781 133.135 1.00 49.96  ? 404 LEU A N   1 
ATOM   2631 C  CA  . LEU A 1 404 ? 105.031 147.623 133.887 1.00 49.96  ? 404 LEU A CA  1 
ATOM   2632 C  C   . LEU A 1 404 ? 105.397 146.326 133.175 1.00 49.96  ? 404 LEU A C   1 
ATOM   2633 O  O   . LEU A 1 404 ? 105.753 145.336 133.813 1.00 49.96  ? 404 LEU A O   1 
ATOM   2634 C  CB  . LEU A 1 404 ? 103.513 147.686 134.107 1.00 49.96  ? 404 LEU A CB  1 
ATOM   2635 C  CG  . LEU A 1 404 ? 102.955 148.468 135.300 1.00 49.96  ? 404 LEU A CG  1 
ATOM   2636 C  CD1 . LEU A 1 404 ? 102.956 149.961 135.035 1.00 49.96  ? 404 LEU A CD1 1 
ATOM   2637 C  CD2 . LEU A 1 404 ? 101.554 147.986 135.650 1.00 49.96  ? 404 LEU A CD2 1 
ATOM   2638 N  N   . ALA A 1 415 ? 104.582 145.996 139.817 1.00 76.71  ? 415 ALA A N   1 
ATOM   2639 C  CA  . ALA A 1 415 ? 105.972 146.149 140.229 1.00 76.71  ? 415 ALA A CA  1 
ATOM   2640 C  C   . ALA A 1 415 ? 106.602 147.366 139.561 1.00 76.71  ? 415 ALA A C   1 
ATOM   2641 O  O   . ALA A 1 415 ? 107.645 147.855 139.998 1.00 76.71  ? 415 ALA A O   1 
ATOM   2642 C  CB  . ALA A 1 415 ? 106.762 144.894 139.902 1.00 76.71  ? 415 ALA A CB  1 
ATOM   2643 N  N   . PHE A 1 416 ? 105.965 147.830 138.483 1.00 71.25  ? 416 PHE A N   1 
ATOM   2644 C  CA  . PHE A 1 416 ? 106.385 149.011 137.734 1.00 71.25  ? 416 PHE A CA  1 
ATOM   2645 C  C   . PHE A 1 416 ? 107.747 148.828 137.072 1.00 71.25  ? 416 PHE A C   1 
ATOM   2646 O  O   . PHE A 1 416 ? 108.285 149.774 136.489 1.00 71.25  ? 416 PHE A O   1 
ATOM   2647 C  CB  . PHE A 1 416 ? 106.395 150.252 138.632 1.00 71.25  ? 416 PHE A CB  1 
ATOM   2648 C  CG  . PHE A 1 416 ? 105.029 150.695 139.069 1.00 71.25  ? 416 PHE A CG  1 
ATOM   2649 C  CD1 . PHE A 1 416 ? 103.894 150.210 138.440 1.00 71.25  ? 416 PHE A CD1 1 
ATOM   2650 C  CD2 . PHE A 1 416 ? 104.878 151.601 140.104 1.00 71.25  ? 416 PHE A CD2 1 
ATOM   2651 C  CE1 . PHE A 1 416 ? 102.634 150.617 138.838 1.00 71.25  ? 416 PHE A CE1 1 
ATOM   2652 C  CE2 . PHE A 1 416 ? 103.619 152.013 140.507 1.00 71.25  ? 416 PHE A CE2 1 
ATOM   2653 C  CZ  . PHE A 1 416 ? 102.496 151.519 139.873 1.00 71.25  ? 416 PHE A CZ  1 
ATOM   2654 N  N   . ASP A 1 417 ? 108.316 147.628 137.151 1.00 62.47  ? 417 ASP A N   1 
ATOM   2655 C  CA  . ASP A 1 417 ? 109.541 147.351 136.416 1.00 62.47  ? 417 ASP A CA  1 
ATOM   2656 C  C   . ASP A 1 417 ? 109.249 147.296 134.921 1.00 62.47  ? 417 ASP A C   1 
ATOM   2657 O  O   . ASP A 1 417 ? 108.237 146.740 134.487 1.00 62.47  ? 417 ASP A O   1 
ATOM   2658 C  CB  . ASP A 1 417 ? 110.163 146.037 136.890 1.00 62.47  ? 417 ASP A CB  1 
ATOM   2659 C  CG  . ASP A 1 417 ? 109.152 144.912 136.985 1.00 62.47  ? 417 ASP A CG  1 
ATOM   2660 O  OD1 . ASP A 1 417 ? 107.941 145.184 136.848 1.00 62.47  ? 417 ASP A OD1 1 
ATOM   2661 O  OD2 . ASP A 1 417 ? 109.568 143.754 137.199 1.00 62.47  ? 417 ASP A OD2 1 
ATOM   2662 N  N   . TYR A 1 418 ? 110.144 147.882 134.131 1.00 35.29  ? 418 TYR A N   1 
ATOM   2663 C  CA  . TYR A 1 418 ? 109.954 147.978 132.693 1.00 35.29  ? 418 TYR A CA  1 
ATOM   2664 C  C   . TYR A 1 418 ? 110.242 146.637 132.018 1.00 35.29  ? 418 TYR A C   1 
ATOM   2665 O  O   . TYR A 1 418 ? 110.578 145.640 132.662 1.00 35.29  ? 418 TYR A O   1 
ATOM   2666 C  CB  . TYR A 1 418 ? 110.839 149.080 132.118 1.00 35.29  ? 418 TYR A CB  1 
ATOM   2667 C  CG  . TYR A 1 418 ? 112.319 148.832 132.304 1.00 35.29  ? 418 TYR A CG  1 
ATOM   2668 C  CD1 . TYR A 1 418 ? 112.959 149.185 133.482 1.00 35.29  ? 418 TYR A CD1 1 
ATOM   2669 C  CD2 . TYR A 1 418 ? 113.071 148.221 131.313 1.00 35.29  ? 418 TYR A CD2 1 
ATOM   2670 C  CE1 . TYR A 1 418 ? 114.305 148.957 133.657 1.00 35.29  ? 418 TYR A CE1 1 
ATOM   2671 C  CE2 . TYR A 1 418 ? 114.416 147.988 131.479 1.00 35.29  ? 418 TYR A CE2 1 
ATOM   2672 C  CZ  . TYR A 1 418 ? 115.028 148.356 132.653 1.00 35.29  ? 418 TYR A CZ  1 
ATOM   2673 O  OH  . TYR A 1 418 ? 116.372 148.122 132.822 1.00 35.29  ? 418 TYR A OH  1 
ATOM   2674 N  N   . SER A 1 419 ? 110.102 146.618 130.687 1.00 28.47  ? 419 SER A N   1 
ATOM   2675 C  CA  . SER A 1 419 ? 110.391 145.469 129.845 1.00 28.47  ? 419 SER A CA  1 
ATOM   2676 C  C   . SER A 1 419 ? 111.594 145.754 128.952 1.00 28.47  ? 419 SER A C   1 
ATOM   2677 O  O   . SER A 1 419 ? 111.654 146.807 128.310 1.00 28.47  ? 419 SER A O   1 
ATOM   2678 C  CB  . SER A 1 419 ? 109.185 145.106 128.974 1.00 28.47  ? 419 SER A CB  1 
ATOM   2679 O  OG  . SER A 1 419 ? 108.099 144.674 129.773 1.00 28.47  ? 419 SER A OG  1 
ATOM   2680 N  N   . PRO A 1 420 ? 112.561 144.844 128.893 1.00 19.13  ? 420 PRO A N   1 
ATOM   2681 C  CA  . PRO A 1 420 ? 113.837 145.155 128.235 1.00 19.13  ? 420 PRO A CA  1 
ATOM   2682 C  C   . PRO A 1 420 ? 113.895 144.854 126.743 1.00 19.13  ? 420 PRO A C   1 
ATOM   2683 O  O   . PRO A 1 420 ? 114.993 144.761 126.189 1.00 19.13  ? 420 PRO A O   1 
ATOM   2684 C  CB  . PRO A 1 420 ? 114.829 144.284 129.009 1.00 19.13  ? 420 PRO A CB  1 
ATOM   2685 C  CG  . PRO A 1 420 ? 114.027 143.107 129.434 1.00 19.13  ? 420 PRO A CG  1 
ATOM   2686 C  CD  . PRO A 1 420 ? 112.604 143.562 129.614 1.00 19.13  ? 420 PRO A CD  1 
ATOM   2687 N  N   . LEU A 1 421 ? 112.737 144.687 126.099 1.00 17.63  ? 421 LEU A N   1 
ATOM   2688 C  CA  . LEU A 1 421 ? 112.575 144.324 124.688 1.00 17.63  ? 421 LEU A CA  1 
ATOM   2689 C  C   . LEU A 1 421 ? 112.881 142.856 124.420 1.00 17.63  ? 421 LEU A C   1 
ATOM   2690 O  O   . LEU A 1 421 ? 112.512 142.334 123.364 1.00 17.63  ? 421 LEU A O   1 
ATOM   2691 C  CB  . LEU A 1 421 ? 113.471 145.163 123.766 1.00 17.63  ? 421 LEU A CB  1 
ATOM   2692 C  CG  . LEU A 1 421 ? 113.342 146.671 123.575 1.00 17.63  ? 421 LEU A CG  1 
ATOM   2693 C  CD1 . LEU A 1 421 ? 114.710 147.256 123.305 1.00 17.63  ? 421 LEU A CD1 1 
ATOM   2694 C  CD2 . LEU A 1 421 ? 112.412 146.979 122.426 1.00 17.63  ? 421 LEU A CD2 1 
ATOM   2695 N  N   . ILE A 1 422 ? 113.499 142.171 125.382 1.00 15.09  ? 422 ILE A N   1 
ATOM   2696 C  CA  . ILE A 1 422 ? 113.751 140.733 125.323 1.00 15.09  ? 422 ILE A CA  1 
ATOM   2697 C  C   . ILE A 1 422 ? 113.844 140.192 126.740 1.00 15.09  ? 422 ILE A C   1 
ATOM   2698 O  O   . ILE A 1 422 ? 114.647 140.669 127.548 1.00 15.09  ? 422 ILE A O   1 
ATOM   2699 C  CB  . ILE A 1 422 ? 115.037 140.366 124.550 1.00 15.09  ? 422 ILE A CB  1 
ATOM   2700 C  CG1 . ILE A 1 422 ? 114.959 140.717 123.068 1.00 15.09  ? 422 ILE A CG1 1 
ATOM   2701 C  CG2 . ILE A 1 422 ? 115.353 138.891 124.704 1.00 15.09  ? 422 ILE A CG2 1 
ATOM   2702 C  CD1 . ILE A 1 422 ? 116.272 140.581 122.366 1.00 15.09  ? 422 ILE A CD1 1 
ATOM   2703 N  N   . THR A 1 423 ? 113.045 139.181 127.042 1.00 14.75  ? 423 THR A N   1 
ATOM   2704 C  CA  . THR A 1 423 ? 113.215 138.392 128.249 1.00 14.75  ? 423 THR A CA  1 
ATOM   2705 C  C   . THR A 1 423 ? 114.081 137.188 127.905 1.00 14.75  ? 423 THR A C   1 
ATOM   2706 O  O   . THR A 1 423 ? 114.051 136.692 126.777 1.00 14.75  ? 423 THR A O   1 
ATOM   2707 C  CB  . THR A 1 423 ? 111.860 137.944 128.804 1.00 14.75  ? 423 THR A CB  1 
ATOM   2708 O  OG1 . THR A 1 423 ? 111.015 139.089 128.970 1.00 14.75  ? 423 THR A OG1 1 
ATOM   2709 C  CG2 . THR A 1 423 ? 112.023 137.257 130.151 1.00 14.75  ? 423 THR A CG2 1 
ATOM   2710 N  N   . TRP A 1 424 ? 114.877 136.733 128.876 1.00 11.96  ? 424 TRP A N   1 
ATOM   2711 C  CA  . TRP A 1 424 ? 115.764 135.606 128.610 1.00 11.96  ? 424 TRP A CA  1 
ATOM   2712 C  C   . TRP A 1 424 ? 114.992 134.378 128.147 1.00 11.96  ? 424 TRP A C   1 
ATOM   2713 O  O   . TRP A 1 424 ? 115.544 133.536 127.431 1.00 11.96  ? 424 TRP A O   1 
ATOM   2714 C  CB  . TRP A 1 424 ? 116.596 135.265 129.845 1.00 11.96  ? 424 TRP A CB  1 
ATOM   2715 C  CG  . TRP A 1 424 ? 117.510 134.109 129.599 1.00 11.96  ? 424 TRP A CG  1 
ATOM   2716 C  CD1 . TRP A 1 424 ? 117.270 132.801 129.891 1.00 11.96  ? 424 TRP A CD1 1 
ATOM   2717 C  CD2 . TRP A 1 424 ? 118.800 134.150 128.979 1.00 11.96  ? 424 TRP A CD2 1 
ATOM   2718 N  NE1 . TRP A 1 424 ? 118.331 132.027 129.500 1.00 11.96  ? 424 TRP A NE1 1 
ATOM   2719 C  CE2 . TRP A 1 424 ? 119.286 132.831 128.940 1.00 11.96  ? 424 TRP A CE2 1 
ATOM   2720 C  CE3 . TRP A 1 424 ? 119.594 135.176 128.459 1.00 11.96  ? 424 TRP A CE3 1 
ATOM   2721 C  CZ2 . TRP A 1 424 ? 120.527 132.510 128.402 1.00 11.96  ? 424 TRP A CZ2 1 
ATOM   2722 C  CZ3 . TRP A 1 424 ? 120.826 134.854 127.927 1.00 11.96  ? 424 TRP A CZ3 1 
ATOM   2723 C  CH2 . TRP A 1 424 ? 121.281 133.533 127.902 1.00 11.96  ? 424 TRP A CH2 1 
ATOM   2724 N  N   . LYS A 1 425 ? 113.722 134.255 128.536 1.00 13.66  ? 425 LYS A N   1 
ATOM   2725 C  CA  . LYS A 1 425 ? 112.904 133.161 128.025 1.00 13.66  ? 425 LYS A CA  1 
ATOM   2726 C  C   . LYS A 1 425 ? 112.730 133.266 126.517 1.00 13.66  ? 425 LYS A C   1 
ATOM   2727 O  O   . LYS A 1 425 ? 112.783 132.255 125.807 1.00 13.66  ? 425 LYS A O   1 
ATOM   2728 C  CB  . LYS A 1 425 ? 111.544 133.150 128.720 1.00 13.66  ? 425 LYS A CB  1 
ATOM   2729 C  CG  . LYS A 1 425 ? 111.617 132.929 130.216 1.00 13.66  ? 425 LYS A CG  1 
ATOM   2730 C  CD  . LYS A 1 425 ? 112.049 131.513 130.545 1.00 13.66  ? 425 LYS A CD  1 
ATOM   2731 C  CE  . LYS A 1 425 ? 112.153 131.309 132.046 1.00 13.66  ? 425 LYS A CE  1 
ATOM   2732 N  NZ  . LYS A 1 425 ? 110.823 131.399 132.708 1.00 13.66  ? 425 LYS A NZ  1 
ATOM   2733 N  N   . GLU A 1 426 ? 112.515 134.481 126.008 1.00 14.37  ? 426 GLU A N   1 
ATOM   2734 C  CA  . GLU A 1 426 ? 112.365 134.666 124.569 1.00 14.37  ? 426 GLU A CA  1 
ATOM   2735 C  C   . GLU A 1 426 ? 113.655 134.340 123.828 1.00 14.37  ? 426 GLU A C   1 
ATOM   2736 O  O   . GLU A 1 426 ? 113.624 133.708 122.767 1.00 14.37  ? 426 GLU A O   1 
ATOM   2737 C  CB  . GLU A 1 426 ? 111.916 136.094 124.269 1.00 14.37  ? 426 GLU A CB  1 
ATOM   2738 C  CG  . GLU A 1 426 ? 110.494 136.389 124.708 1.00 14.37  ? 426 GLU A CG  1 
ATOM   2739 C  CD  . GLU A 1 426 ? 110.279 137.844 125.066 1.00 14.37  ? 426 GLU A CD  1 
ATOM   2740 O  OE1 . GLU A 1 426 ? 111.142 138.676 124.719 1.00 14.37  ? 426 GLU A OE1 1 
ATOM   2741 O  OE2 . GLU A 1 426 ? 109.247 138.156 125.693 1.00 14.37  ? 426 GLU A OE2 1 
ATOM   2742 N  N   . PHE A 1 427 ? 114.799 134.767 124.367 1.00 11.73  ? 427 PHE A N   1 
ATOM   2743 C  CA  . PHE A 1 427 ? 116.077 134.453 123.736 1.00 11.73  ? 427 PHE A CA  1 
ATOM   2744 C  C   . PHE A 1 427 ? 116.355 132.955 123.770 1.00 11.73  ? 427 PHE A C   1 
ATOM   2745 O  O   . PHE A 1 427 ? 116.891 132.392 122.809 1.00 11.73  ? 427 PHE A O   1 
ATOM   2746 C  CB  . PHE A 1 427 ? 117.202 135.225 124.422 1.00 11.73  ? 427 PHE A CB  1 
ATOM   2747 C  CG  . PHE A 1 427 ? 118.579 134.783 124.018 1.00 11.73  ? 427 PHE A CG  1 
ATOM   2748 C  CD1 . PHE A 1 427 ? 119.134 135.206 122.826 1.00 11.73  ? 427 PHE A CD1 1 
ATOM   2749 C  CD2 . PHE A 1 427 ? 119.321 133.949 124.834 1.00 11.73  ? 427 PHE A CD2 1 
ATOM   2750 C  CE1 . PHE A 1 427 ? 120.399 134.804 122.456 1.00 11.73  ? 427 PHE A CE1 1 
ATOM   2751 C  CE2 . PHE A 1 427 ? 120.586 133.543 124.466 1.00 11.73  ? 427 PHE A CE2 1 
ATOM   2752 C  CZ  . PHE A 1 427 ? 121.124 133.972 123.276 1.00 11.73  ? 427 PHE A CZ  1 
ATOM   2753 N  N   . GLN A 1 428 ? 116.000 132.295 124.874 1.00 13.29  ? 428 GLN A N   1 
ATOM   2754 C  CA  . GLN A 1 428 ? 116.254 130.864 125.006 1.00 13.29  ? 428 GLN A CA  1 
ATOM   2755 C  C   . GLN A 1 428 ? 115.419 130.056 124.022 1.00 13.29  ? 428 GLN A C   1 
ATOM   2756 O  O   . GLN A 1 428 ? 115.825 128.968 123.599 1.00 13.29  ? 428 GLN A O   1 
ATOM   2757 C  CB  . GLN A 1 428 ? 115.969 130.418 126.438 1.00 13.29  ? 428 GLN A CB  1 
ATOM   2758 C  CG  . GLN A 1 428 ? 116.615 129.104 126.820 1.00 13.29  ? 428 GLN A CG  1 
ATOM   2759 C  CD  . GLN A 1 428 ? 116.435 128.777 128.285 1.00 13.29  ? 428 GLN A CD  1 
ATOM   2760 O  OE1 . GLN A 1 428 ? 116.142 129.653 129.096 1.00 13.29  ? 428 GLN A OE1 1 
ATOM   2761 N  NE2 . GLN A 1 428 ? 116.603 127.508 128.632 1.00 13.29  ? 428 GLN A NE2 1 
ATOM   2762 N  N   . SER A 1 429 ? 114.248 130.567 123.648 1.00 13.65  ? 429 SER A N   1 
ATOM   2763 C  CA  . SER A 1 429 ? 113.321 129.828 122.790 1.00 13.65  ? 429 SER A CA  1 
ATOM   2764 C  C   . SER A 1 429 ? 113.563 130.195 121.326 1.00 13.65  ? 429 SER A C   1 
ATOM   2765 O  O   . SER A 1 429 ? 112.772 129.900 120.429 1.00 13.65  ? 429 SER A O   1 
ATOM   2766 C  CB  . SER A 1 429 ? 111.883 130.102 123.206 1.00 13.65  ? 429 SER A CB  1 
ATOM   2767 O  OG  . SER A 1 429 ? 111.424 131.325 122.658 1.00 13.65  ? 429 SER A OG  1 
ATOM   2768 N  N   . PHE A 1 430 ? 114.696 130.856 121.094 1.00 13.79  ? 430 PHE A N   1 
ATOM   2769 C  CA  . PHE A 1 430 ? 115.055 131.288 119.750 1.00 13.79  ? 430 PHE A CA  1 
ATOM   2770 C  C   . PHE A 1 430 ? 116.485 130.885 119.417 1.00 13.79  ? 430 PHE A C   1 
ATOM   2771 O  O   . PHE A 1 430 ? 116.833 130.718 118.245 1.00 13.79  ? 430 PHE A O   1 
ATOM   2772 C  CB  . PHE A 1 430 ? 114.872 132.802 119.618 1.00 13.79  ? 430 PHE A CB  1 
ATOM   2773 C  CG  . PHE A 1 430 ? 114.797 133.285 118.198 1.00 13.79  ? 430 PHE A CG  1 
ATOM   2774 C  CD1 . PHE A 1 430 ? 115.949 133.482 117.455 1.00 13.79  ? 430 PHE A CD1 1 
ATOM   2775 C  CD2 . PHE A 1 430 ? 113.575 133.535 117.603 1.00 13.79  ? 430 PHE A CD2 1 
ATOM   2776 C  CE1 . PHE A 1 430 ? 115.883 133.921 116.150 1.00 13.79  ? 430 PHE A CE1 1 
ATOM   2777 C  CE2 . PHE A 1 430 ? 113.505 133.974 116.296 1.00 13.79  ? 430 PHE A CE2 1 
ATOM   2778 C  CZ  . PHE A 1 430 ? 114.660 134.167 115.570 1.00 13.79  ? 430 PHE A CZ  1 
ATOM   2779 N  N   . MET A 1 431 ? 117.308 130.703 120.437 1.00 12.01  ? 431 MET A N   1 
ATOM   2780 C  CA  . MET A 1 431 ? 118.710 130.377 120.214 1.00 12.01  ? 431 MET A CA  1 
ATOM   2781 C  C   . MET A 1 431 ? 118.846 128.947 119.704 1.00 12.01  ? 431 MET A C   1 
ATOM   2782 O  O   . MET A 1 431 ? 118.327 128.017 120.332 1.00 12.01  ? 431 MET A O   1 
ATOM   2783 C  CB  . MET A 1 431 ? 119.500 130.559 121.505 1.00 12.01  ? 431 MET A CB  1 
ATOM   2784 C  CG  . MET A 1 431 ? 120.939 130.098 121.431 1.00 12.01  ? 431 MET A CG  1 
ATOM   2785 S  SD  . MET A 1 431 ? 121.975 131.090 120.352 1.00 12.01  ? 431 MET A SD  1 
ATOM   2786 C  CE  . MET A 1 431 ? 123.492 130.145 120.420 1.00 12.01  ? 431 MET A CE  1 
ATOM   2787 N  N   . PRO A 1 432 ? 119.518 128.728 118.572 1.00 12.77  ? 432 PRO A N   1 
ATOM   2788 C  CA  . PRO A 1 432 ? 119.733 127.357 118.094 1.00 12.77  ? 432 PRO A CA  1 
ATOM   2789 C  C   . PRO A 1 432 ? 120.780 126.620 118.911 1.00 12.77  ? 432 PRO A C   1 
ATOM   2790 O  O   . PRO A 1 432 ? 121.939 126.528 118.498 1.00 12.77  ? 432 PRO A O   1 
ATOM   2791 C  CB  . PRO A 1 432 ? 120.201 127.561 116.646 1.00 12.77  ? 432 PRO A CB  1 
ATOM   2792 C  CG  . PRO A 1 432 ? 119.795 128.960 116.299 1.00 12.77  ? 432 PRO A CG  1 
ATOM   2793 C  CD  . PRO A 1 432 ? 119.939 129.720 117.574 1.00 12.77  ? 432 PRO A CD  1 
ATOM   2794 N  N   . TRP A 1 433 ? 120.387 126.098 120.073 1.00 12.75  ? 433 TRP A N   1 
ATOM   2795 C  CA  . TRP A 1 433 ? 121.335 125.385 120.922 1.00 12.75  ? 433 TRP A CA  1 
ATOM   2796 C  C   . TRP A 1 433 ? 121.832 124.107 120.260 1.00 12.75  ? 433 TRP A C   1 
ATOM   2797 O  O   . TRP A 1 433 ? 122.998 123.728 120.436 1.00 12.75  ? 433 TRP A O   1 
ATOM   2798 C  CB  . TRP A 1 433 ? 120.691 125.076 122.270 1.00 12.75  ? 433 TRP A CB  1 
ATOM   2799 C  CG  . TRP A 1 433 ? 120.157 126.288 122.966 1.00 12.75  ? 433 TRP A CG  1 
ATOM   2800 C  CD1 . TRP A 1 433 ? 118.851 126.659 123.077 1.00 12.75  ? 433 TRP A CD1 1 
ATOM   2801 C  CD2 . TRP A 1 433 ? 120.917 127.288 123.654 1.00 12.75  ? 433 TRP A CD2 1 
ATOM   2802 N  NE1 . TRP A 1 433 ? 118.749 127.828 123.788 1.00 12.75  ? 433 TRP A NE1 1 
ATOM   2803 C  CE2 . TRP A 1 433 ? 120.004 128.234 124.155 1.00 12.75  ? 433 TRP A CE2 1 
ATOM   2804 C  CE3 . TRP A 1 433 ? 122.281 127.474 123.895 1.00 12.75  ? 433 TRP A CE3 1 
ATOM   2805 C  CZ2 . TRP A 1 433 ? 120.409 129.349 124.880 1.00 12.75  ? 433 TRP A CZ2 1 
ATOM   2806 C  CZ3 . TRP A 1 433 ? 122.680 128.581 124.615 1.00 12.75  ? 433 TRP A CZ3 1 
ATOM   2807 C  CH2 . TRP A 1 433 ? 121.748 129.504 125.099 1.00 12.75  ? 433 TRP A CH2 1 
ATOM   2808 N  N   . ASP A 1 434 ? 120.967 123.433 119.500 1.00 12.65  ? 434 ASP A N   1 
ATOM   2809 C  CA  . ASP A 1 434 ? 121.383 122.235 118.781 1.00 12.65  ? 434 ASP A CA  1 
ATOM   2810 C  C   . ASP A 1 434 ? 122.468 122.552 117.761 1.00 12.65  ? 434 ASP A C   1 
ATOM   2811 O  O   . ASP A 1 434 ? 123.418 121.778 117.598 1.00 12.65  ? 434 ASP A O   1 
ATOM   2812 C  CB  . ASP A 1 434 ? 120.177 121.591 118.101 1.00 12.65  ? 434 ASP A CB  1 
ATOM   2813 C  CG  . ASP A 1 434 ? 119.270 122.606 117.437 1.00 12.65  ? 434 ASP A CG  1 
ATOM   2814 O  OD1 . ASP A 1 434 ? 119.722 123.746 117.209 1.00 12.65  ? 434 ASP A OD1 1 
ATOM   2815 O  OD2 . ASP A 1 434 ? 118.104 122.268 117.149 1.00 12.65  ? 434 ASP A OD2 1 
ATOM   2816 N  N   . ILE A 1 435 ? 122.344 123.685 117.069 1.00 13.18  ? 435 ILE A N   1 
ATOM   2817 C  CA  . ILE A 1 435 ? 123.374 124.101 116.122 1.00 13.18  ? 435 ILE A CA  1 
ATOM   2818 C  C   . ILE A 1 435 ? 124.692 124.350 116.842 1.00 13.18  ? 435 ILE A C   1 
ATOM   2819 O  O   . ILE A 1 435 ? 125.765 123.965 116.359 1.00 13.18  ? 435 ILE A O   1 
ATOM   2820 C  CB  . ILE A 1 435 ? 122.909 125.346 115.345 1.00 13.18  ? 435 ILE A CB  1 
ATOM   2821 C  CG1 . ILE A 1 435 ? 121.813 124.969 114.349 1.00 13.18  ? 435 ILE A CG1 1 
ATOM   2822 C  CG2 . ILE A 1 435 ? 124.077 126.004 114.637 1.00 13.18  ? 435 ILE A CG2 1 
ATOM   2823 C  CD1 . ILE A 1 435 ? 122.149 123.763 113.509 1.00 13.18  ? 435 ILE A CD1 1 
ATOM   2824 N  N   . ALA A 1 436 ? 124.635 125.003 118.004 1.00 10.99  ? 436 ALA A N   1 
ATOM   2825 C  CA  . ALA A 1 436 ? 125.849 125.257 118.770 1.00 10.99  ? 436 ALA A CA  1 
ATOM   2826 C  C   . ALA A 1 436 ? 126.527 123.955 119.175 1.00 10.99  ? 436 ALA A C   1 
ATOM   2827 O  O   . ALA A 1 436 ? 127.748 123.812 119.035 1.00 10.99  ? 436 ALA A O   1 
ATOM   2828 C  CB  . ALA A 1 436 ? 125.522 126.098 120.002 1.00 10.99  ? 436 ALA A CB  1 
ATOM   2829 N  N   . ILE A 1 437 ? 125.748 122.988 119.663 1.00 10.26  ? 437 ILE A N   1 
ATOM   2830 C  CA  . ILE A 1 437 ? 126.326 121.709 120.067 1.00 10.26  ? 437 ILE A CA  1 
ATOM   2831 C  C   . ILE A 1 437 ? 126.898 120.972 118.862 1.00 10.26  ? 437 ILE A C   1 
ATOM   2832 O  O   . ILE A 1 437 ? 127.959 120.345 118.951 1.00 10.26  ? 437 ILE A O   1 
ATOM   2833 C  CB  . ILE A 1 437 ? 125.282 120.862 120.815 1.00 10.26  ? 437 ILE A CB  1 
ATOM   2834 C  CG1 . ILE A 1 437 ? 124.967 121.492 122.170 1.00 10.26  ? 437 ILE A CG1 1 
ATOM   2835 C  CG2 . ILE A 1 437 ? 125.775 119.441 121.004 1.00 10.26  ? 437 ILE A CG2 1 
ATOM   2836 C  CD1 . ILE A 1 437 ? 123.845 120.815 122.904 1.00 10.26  ? 437 ILE A CD1 1 
ATOM   2837 N  N   . LEU A 1 438 ? 126.214 121.035 117.718 1.00 10.11  ? 438 LEU A N   1 
ATOM   2838 C  CA  . LEU A 1 438 ? 126.699 120.357 116.519 1.00 10.11  ? 438 LEU A CA  1 
ATOM   2839 C  C   . LEU A 1 438 ? 128.028 120.942 116.049 1.00 10.11  ? 438 LEU A C   1 
ATOM   2840 O  O   . LEU A 1 438 ? 128.970 120.205 115.724 1.00 10.11  ? 438 LEU A O   1 
ATOM   2841 C  CB  . LEU A 1 438 ? 125.639 120.446 115.422 1.00 10.11  ? 438 LEU A CB  1 
ATOM   2842 C  CG  . LEU A 1 438 ? 125.998 119.958 114.023 1.00 10.11  ? 438 LEU A CG  1 
ATOM   2843 C  CD1 . LEU A 1 438 ? 126.145 118.452 114.010 1.00 10.11  ? 438 LEU A CD1 1 
ATOM   2844 C  CD2 . LEU A 1 438 ? 124.935 120.398 113.037 1.00 10.11  ? 438 LEU A CD2 1 
ATOM   2845 N  N   . VAL A 1 439 ? 128.127 122.273 116.019 1.00 11.01  ? 439 VAL A N   1 
ATOM   2846 C  CA  . VAL A 1 439 ? 129.369 122.907 115.589 1.00 11.01  ? 439 VAL A CA  1 
ATOM   2847 C  C   . VAL A 1 439 ? 130.488 122.626 116.585 1.00 11.01  ? 439 VAL A C   1 
ATOM   2848 O  O   . VAL A 1 439 ? 131.640 122.392 116.196 1.00 11.01  ? 439 VAL A O   1 
ATOM   2849 C  CB  . VAL A 1 439 ? 129.157 124.415 115.376 1.00 11.01  ? 439 VAL A CB  1 
ATOM   2850 C  CG1 . VAL A 1 439 ? 130.442 125.065 114.910 1.00 11.01  ? 439 VAL A CG1 1 
ATOM   2851 C  CG2 . VAL A 1 439 ? 128.061 124.650 114.358 1.00 11.01  ? 439 VAL A CG2 1 
ATOM   2852 N  N   . GLY A 1 440 ? 130.175 122.640 117.883 1.00 12.28  ? 440 GLY A N   1 
ATOM   2853 C  CA  . GLY A 1 440 ? 131.180 122.293 118.873 1.00 12.28  ? 440 GLY A CA  1 
ATOM   2854 C  C   . GLY A 1 440 ? 131.670 120.866 118.728 1.00 12.28  ? 440 GLY A C   1 
ATOM   2855 O  O   . GLY A 1 440 ? 132.861 120.589 118.886 1.00 12.28  ? 440 GLY A O   1 
ATOM   2856 N  N   . GLY A 1 441 ? 130.757 119.939 118.435 1.00 13.73  ? 441 GLY A N   1 
ATOM   2857 C  CA  . GLY A 1 441 ? 131.163 118.565 118.197 1.00 13.73  ? 441 GLY A CA  1 
ATOM   2858 C  C   . GLY A 1 441 ? 132.066 118.432 116.988 1.00 13.73  ? 441 GLY A C   1 
ATOM   2859 O  O   . GLY A 1 441 ? 133.045 117.683 117.011 1.00 13.73  ? 441 GLY A O   1 
ATOM   2860 N  N   . GLY A 1 442 ? 131.751 119.162 115.915 1.00 12.40  ? 442 GLY A N   1 
ATOM   2861 C  CA  . GLY A 1 442 ? 132.641 119.175 114.764 1.00 12.40  ? 442 GLY A CA  1 
ATOM   2862 C  C   . GLY A 1 442 ? 134.021 119.710 115.100 1.00 12.40  ? 442 GLY A C   1 
ATOM   2863 O  O   . GLY A 1 442 ? 135.038 119.147 114.682 1.00 12.40  ? 442 GLY A O   1 
ATOM   2864 N  N   . PHE A 1 443 ? 134.074 120.799 115.873 1.00 13.63  ? 443 PHE A N   1 
ATOM   2865 C  CA  . PHE A 1 443 ? 135.358 121.362 116.282 1.00 13.63  ? 443 PHE A CA  1 
ATOM   2866 C  C   . PHE A 1 443 ? 136.162 120.371 117.111 1.00 13.63  ? 443 PHE A C   1 
ATOM   2867 O  O   . PHE A 1 443 ? 137.371 120.210 116.903 1.00 13.63  ? 443 PHE A O   1 
ATOM   2868 C  CB  . PHE A 1 443 ? 135.141 122.648 117.076 1.00 13.63  ? 443 PHE A CB  1 
ATOM   2869 C  CG  . PHE A 1 443 ? 134.926 123.858 116.225 1.00 13.63  ? 443 PHE A CG  1 
ATOM   2870 C  CD1 . PHE A 1 443 ? 135.691 124.068 115.094 1.00 13.63  ? 443 PHE A CD1 1 
ATOM   2871 C  CD2 . PHE A 1 443 ? 133.965 124.793 116.565 1.00 13.63  ? 443 PHE A CD2 1 
ATOM   2872 C  CE1 . PHE A 1 443 ? 135.495 125.185 114.313 1.00 13.63  ? 443 PHE A CE1 1 
ATOM   2873 C  CE2 . PHE A 1 443 ? 133.765 125.910 115.788 1.00 13.63  ? 443 PHE A CE2 1 
ATOM   2874 C  CZ  . PHE A 1 443 ? 134.529 126.108 114.661 1.00 13.63  ? 443 PHE A CZ  1 
ATOM   2875 N  N   . ALA A 1 444 ? 135.509 119.704 118.064 1.00 13.67  ? 444 ALA A N   1 
ATOM   2876 C  CA  . ALA A 1 444 ? 136.215 118.753 118.915 1.00 13.67  ? 444 ALA A CA  1 
ATOM   2877 C  C   . ALA A 1 444 ? 136.698 117.554 118.116 1.00 13.67  ? 444 ALA A C   1 
ATOM   2878 O  O   . ALA A 1 444 ? 137.802 117.048 118.350 1.00 13.67  ? 444 ALA A O   1 
ATOM   2879 C  CB  . ALA A 1 444 ? 135.315 118.301 120.060 1.00 13.67  ? 444 ALA A CB  1 
ATOM   2880 N  N   . LEU A 1 445 ? 135.886 117.083 117.169 1.00 15.34  ? 445 LEU A N   1 
ATOM   2881 C  CA  . LEU A 1 445 ? 136.311 115.977 116.320 1.00 15.34  ? 445 LEU A CA  1 
ATOM   2882 C  C   . LEU A 1 445 ? 137.528 116.362 115.491 1.00 15.34  ? 445 LEU A C   1 
ATOM   2883 O  O   . LEU A 1 445 ? 138.485 115.587 115.386 1.00 15.34  ? 445 LEU A O   1 
ATOM   2884 C  CB  . LEU A 1 445 ? 135.157 115.538 115.421 1.00 15.34  ? 445 LEU A CB  1 
ATOM   2885 C  CG  . LEU A 1 445 ? 135.352 114.241 114.643 1.00 15.34  ? 445 LEU A CG  1 
ATOM   2886 C  CD1 . LEU A 1 445 ? 135.739 113.117 115.586 1.00 15.34  ? 445 LEU A CD1 1 
ATOM   2887 C  CD2 . LEU A 1 445 ? 134.081 113.897 113.890 1.00 15.34  ? 445 LEU A CD2 1 
ATOM   2888 N  N   . ALA A 1 446 ? 137.521 117.565 114.912 1.00 18.81  ? 446 ALA A N   1 
ATOM   2889 C  CA  . ALA A 1 446 ? 138.682 118.009 114.147 1.00 18.81  ? 446 ALA A CA  1 
ATOM   2890 C  C   . ALA A 1 446 ? 139.921 118.108 115.029 1.00 18.81  ? 446 ALA A C   1 
ATOM   2891 O  O   . ALA A 1 446 ? 141.001 117.631 114.653 1.00 18.81  ? 446 ALA A O   1 
ATOM   2892 C  CB  . ALA A 1 446 ? 138.388 119.352 113.482 1.00 18.81  ? 446 ALA A CB  1 
ATOM   2893 N  N   . ASP A 1 447 ? 139.777 118.707 116.216 1.00 22.39  ? 447 ASP A N   1 
ATOM   2894 C  CA  . ASP A 1 447 ? 140.913 118.866 117.119 1.00 22.39  ? 447 ASP A CA  1 
ATOM   2895 C  C   . ASP A 1 447 ? 141.483 117.515 117.526 1.00 22.39  ? 447 ASP A C   1 
ATOM   2896 O  O   . ASP A 1 447 ? 142.706 117.337 117.576 1.00 22.39  ? 447 ASP A O   1 
ATOM   2897 C  CB  . ASP A 1 447 ? 140.492 119.662 118.353 1.00 22.39  ? 447 ASP A CB  1 
ATOM   2898 C  CG  . ASP A 1 447 ? 140.613 121.160 118.151 1.00 22.39  ? 447 ASP A CG  1 
ATOM   2899 O  OD1 . ASP A 1 447 ? 140.685 121.601 116.985 1.00 22.39  ? 447 ASP A OD1 1 
ATOM   2900 O  OD2 . ASP A 1 447 ? 140.631 121.897 119.159 1.00 22.39  ? 447 ASP A OD2 1 
ATOM   2901 N  N   . GLY A 1 448 ? 140.611 116.552 117.825 1.00 21.02  ? 448 GLY A N   1 
ATOM   2902 C  CA  . GLY A 1 448 ? 141.078 115.205 118.094 1.00 21.02  ? 448 GLY A CA  1 
ATOM   2903 C  C   . GLY A 1 448 ? 141.746 114.577 116.889 1.00 21.02  ? 448 GLY A C   1 
ATOM   2904 O  O   . GLY A 1 448 ? 142.649 113.750 117.029 1.00 21.02  ? 448 GLY A O   1 
ATOM   2905 N  N   . CYS A 1 449 ? 141.305 114.952 115.686 1.00 25.86  ? 449 CYS A N   1 
ATOM   2906 C  CA  . CYS A 1 449 ? 141.957 114.450 114.481 1.00 25.86  ? 449 CYS A CA  1 
ATOM   2907 C  C   . CYS A 1 449 ? 143.401 114.929 114.389 1.00 25.86  ? 449 CYS A C   1 
ATOM   2908 O  O   . CYS A 1 449 ? 144.293 114.148 114.041 1.00 25.86  ? 449 CYS A O   1 
ATOM   2909 C  CB  . CYS A 1 449 ? 141.170 114.860 113.238 1.00 25.86  ? 449 CYS A CB  1 
ATOM   2910 S  SG  . CYS A 1 449 ? 139.666 113.904 112.967 1.00 25.86  ? 449 CYS A SG  1 
ATOM   2911 N  N   . GLU A 1 450 ? 143.659 116.208 114.683 1.00 27.12  ? 450 GLU A N   1 
ATOM   2912 C  CA  . GLU A 1 450 ? 145.065 116.628 114.674 1.00 27.12  ? 450 GLU A CA  1 
ATOM   2913 C  C   . GLU A 1 450 ? 145.833 116.026 115.844 1.00 27.12  ? 450 GLU A C   1 
ATOM   2914 O  O   . GLU A 1 450 ? 146.987 115.614 115.684 1.00 27.12  ? 450 GLU A O   1 
ATOM   2915 C  CB  . GLU A 1 450 ? 145.270 118.150 114.674 1.00 27.12  ? 450 GLU A CB  1 
ATOM   2916 C  CG  . GLU A 1 450 ? 144.852 118.894 113.414 1.00 27.12  ? 450 GLU A CG  1 
ATOM   2917 C  CD  . GLU A 1 450 ? 143.432 119.364 113.449 1.00 27.12  ? 450 GLU A CD  1 
ATOM   2918 O  OE1 . GLU A 1 450 ? 142.811 119.230 114.512 1.00 27.12  ? 450 GLU A OE1 1 
ATOM   2919 O  OE2 . GLU A 1 450 ? 142.936 119.853 112.417 1.00 27.12  ? 450 GLU A OE2 1 
ATOM   2920 N  N   . GLU A 1 451 ? 145.219 115.970 117.029 1.00 27.06  ? 451 GLU A N   1 
ATOM   2921 C  CA  . GLU A 1 451 ? 145.942 115.502 118.208 1.00 27.06  ? 451 GLU A CA  1 
ATOM   2922 C  C   . GLU A 1 451 ? 146.324 114.031 118.086 1.00 27.06  ? 451 GLU A C   1 
ATOM   2923 O  O   . GLU A 1 451 ? 147.413 113.630 118.511 1.00 27.06  ? 451 GLU A O   1 
ATOM   2924 C  CB  . GLU A 1 451 ? 145.108 115.739 119.466 1.00 27.06  ? 451 GLU A CB  1 
ATOM   2925 C  CG  . GLU A 1 451 ? 145.829 115.381 120.753 1.00 27.06  ? 451 GLU A CG  1 
ATOM   2926 C  CD  . GLU A 1 451 ? 145.381 116.225 121.929 1.00 27.06  ? 451 GLU A CD  1 
ATOM   2927 O  OE1 . GLU A 1 451 ? 144.644 117.209 121.709 1.00 27.06  ? 451 GLU A OE1 1 
ATOM   2928 O  OE2 . GLU A 1 451 ? 145.768 115.908 123.074 1.00 27.06  ? 451 GLU A OE2 1 
ATOM   2929 N  N   . SER A 1 452 ? 145.442 113.214 117.509 1.00 24.07  ? 452 SER A N   1 
ATOM   2930 C  CA  . SER A 1 452 ? 145.703 111.786 117.386 1.00 24.07  ? 452 SER A CA  1 
ATOM   2931 C  C   . SER A 1 452 ? 146.788 111.471 116.367 1.00 24.07  ? 452 SER A C   1 
ATOM   2932 O  O   . SER A 1 452 ? 147.296 110.345 116.352 1.00 24.07  ? 452 SER A O   1 
ATOM   2933 C  CB  . SER A 1 452 ? 144.416 111.056 117.010 1.00 24.07  ? 452 SER A CB  1 
ATOM   2934 O  OG  . SER A 1 452 ? 144.644 109.668 116.858 1.00 24.07  ? 452 SER A OG  1 
ATOM   2935 N  N   . GLY A 1 453 ? 147.156 112.427 115.522 1.00 28.23  ? 453 GLY A N   1 
ATOM   2936 C  CA  . GLY A 1 453 ? 148.131 112.194 114.481 1.00 28.23  ? 453 GLY A CA  1 
ATOM   2937 C  C   . GLY A 1 453 ? 147.578 111.634 113.192 1.00 28.23  ? 453 GLY A C   1 
ATOM   2938 O  O   . GLY A 1 453 ? 148.363 111.311 112.294 1.00 28.23  ? 453 GLY A O   1 
ATOM   2939 N  N   . LEU A 1 454 ? 146.255 111.504 113.072 1.00 28.10  ? 454 LEU A N   1 
ATOM   2940 C  CA  . LEU A 1 454 ? 145.664 110.998 111.839 1.00 28.10  ? 454 LEU A CA  1 
ATOM   2941 C  C   . LEU A 1 454 ? 145.898 111.946 110.671 1.00 28.10  ? 454 LEU A C   1 
ATOM   2942 O  O   . LEU A 1 454 ? 146.054 111.494 109.530 1.00 28.10  ? 454 LEU A O   1 
ATOM   2943 C  CB  . LEU A 1 454 ? 144.168 110.760 112.036 1.00 28.10  ? 454 LEU A CB  1 
ATOM   2944 C  CG  . LEU A 1 454 ? 143.425 110.066 110.896 1.00 28.10  ? 454 LEU A CG  1 
ATOM   2945 C  CD1 . LEU A 1 454 ? 144.023 108.698 110.623 1.00 28.10  ? 454 LEU A CD1 1 
ATOM   2946 C  CD2 . LEU A 1 454 ? 141.948 109.952 111.221 1.00 28.10  ? 454 LEU A CD2 1 
ATOM   2947 N  N   . SER A 1 455 ? 145.918 113.255 110.930 1.00 32.17  ? 455 SER A N   1 
ATOM   2948 C  CA  . SER A 1 455 ? 146.130 114.222 109.858 1.00 32.17  ? 455 SER A CA  1 
ATOM   2949 C  C   . SER A 1 455 ? 147.502 114.051 109.221 1.00 32.17  ? 455 SER A C   1 
ATOM   2950 O  O   . SER A 1 455 ? 147.643 114.151 107.996 1.00 32.17  ? 455 SER A O   1 
ATOM   2951 C  CB  . SER A 1 455 ? 145.959 115.640 110.397 1.00 32.17  ? 455 SER A CB  1 
ATOM   2952 O  OG  . SER A 1 455 ? 144.628 115.860 110.826 1.00 32.17  ? 455 SER A OG  1 
ATOM   2953 N  N   . LYS A 1 456 ? 148.529 113.803 110.036 1.00 36.78  ? 456 LYS A N   1 
ATOM   2954 C  CA  . LYS A 1 456 ? 149.862 113.566 109.494 1.00 36.78  ? 456 LYS A CA  1 
ATOM   2955 C  C   . LYS A 1 456 ? 149.889 112.315 108.627 1.00 36.78  ? 456 LYS A C   1 
ATOM   2956 O  O   . LYS A 1 456 ? 150.532 112.295 107.571 1.00 36.78  ? 456 LYS A O   1 
ATOM   2957 C  CB  . LYS A 1 456 ? 150.878 113.455 110.629 1.00 36.78  ? 456 LYS A CB  1 
ATOM   2958 C  CG  . LYS A 1 456 ? 152.323 113.523 110.170 1.00 36.78  ? 456 LYS A CG  1 
ATOM   2959 C  CD  . LYS A 1 456 ? 153.250 113.889 111.317 1.00 36.78  ? 456 LYS A CD  1 
ATOM   2960 C  CE  . LYS A 1 456 ? 154.569 114.438 110.802 1.00 36.78  ? 456 LYS A CE  1 
ATOM   2961 N  NZ  . LYS A 1 456 ? 154.361 115.555 109.839 1.00 36.78  ? 456 LYS A NZ  1 
ATOM   2962 N  N   . TRP A 1 457 ? 149.198 111.258 109.060 1.00 38.94  ? 457 TRP A N   1 
ATOM   2963 C  CA  . TRP A 1 457 ? 149.125 110.040 108.260 1.00 38.94  ? 457 TRP A CA  1 
ATOM   2964 C  C   . TRP A 1 457 ? 148.424 110.295 106.932 1.00 38.94  ? 457 TRP A C   1 
ATOM   2965 O  O   . TRP A 1 457 ? 148.859 109.800 105.885 1.00 38.94  ? 457 TRP A O   1 
ATOM   2966 C  CB  . TRP A 1 457 ? 148.409 108.945 109.050 1.00 38.94  ? 457 TRP A CB  1 
ATOM   2967 C  CG  . TRP A 1 457 ? 148.360 107.622 108.355 1.00 38.94  ? 457 TRP A CG  1 
ATOM   2968 C  CD1 . TRP A 1 457 ? 149.272 106.614 108.449 1.00 38.94  ? 457 TRP A CD1 1 
ATOM   2969 C  CD2 . TRP A 1 457 ? 147.342 107.160 107.461 1.00 38.94  ? 457 TRP A CD2 1 
ATOM   2970 N  NE1 . TRP A 1 457 ? 148.887 105.552 107.669 1.00 38.94  ? 457 TRP A NE1 1 
ATOM   2971 C  CE2 . TRP A 1 457 ? 147.704 105.863 107.051 1.00 38.94  ? 457 TRP A CE2 1 
ATOM   2972 C  CE3 . TRP A 1 457 ? 146.160 107.717 106.966 1.00 38.94  ? 457 TRP A CE3 1 
ATOM   2973 C  CZ2 . TRP A 1 457 ? 146.928 105.115 106.171 1.00 38.94  ? 457 TRP A CZ2 1 
ATOM   2974 C  CZ3 . TRP A 1 457 ? 145.391 106.974 106.093 1.00 38.94  ? 457 TRP A CZ3 1 
ATOM   2975 C  CH2 . TRP A 1 457 ? 145.778 105.686 105.704 1.00 38.94  ? 457 TRP A CH2 1 
ATOM   2976 N  N   . ILE A 1 458 ? 147.336 111.069 106.954 1.00 37.43  ? 458 ILE A N   1 
ATOM   2977 C  CA  . ILE A 1 458 ? 146.621 111.389 105.721 1.00 37.43  ? 458 ILE A CA  1 
ATOM   2978 C  C   . ILE A 1 458 ? 147.511 112.192 104.782 1.00 37.43  ? 458 ILE A C   1 
ATOM   2979 O  O   . ILE A 1 458 ? 147.547 111.944 103.571 1.00 37.43  ? 458 ILE A O   1 
ATOM   2980 C  CB  . ILE A 1 458 ? 145.312 112.133 106.039 1.00 37.43  ? 458 ILE A CB  1 
ATOM   2981 C  CG1 . ILE A 1 458 ? 144.330 111.204 106.751 1.00 37.43  ? 458 ILE A CG1 1 
ATOM   2982 C  CG2 . ILE A 1 458 ? 144.685 112.680 104.771 1.00 37.43  ? 458 ILE A CG2 1 
ATOM   2983 C  CD1 . ILE A 1 458 ? 143.074 111.897 107.224 1.00 37.43  ? 458 ILE A CD1 1 
ATOM   2984 N  N   . GLY A 1 459 ? 148.240 113.169 105.323 1.00 45.23  ? 459 GLY A N   1 
ATOM   2985 C  CA  . GLY A 1 459 ? 149.151 113.943 104.494 1.00 45.23  ? 459 GLY A CA  1 
ATOM   2986 C  C   . GLY A 1 459 ? 150.256 113.095 103.893 1.00 45.23  ? 459 GLY A C   1 
ATOM   2987 O  O   . GLY A 1 459 ? 150.610 113.255 102.722 1.00 45.23  ? 459 GLY A O   1 
ATOM   2988 N  N   . ASN A 1 460 ? 150.811 112.176 104.685 1.00 48.07  ? 460 ASN A N   1 
ATOM   2989 C  CA  . ASN A 1 460 ? 151.837 111.279 104.166 1.00 48.07  ? 460 ASN A CA  1 
ATOM   2990 C  C   . ASN A 1 460 ? 151.283 110.396 103.055 1.00 48.07  ? 460 ASN A C   1 
ATOM   2991 O  O   . ASN A 1 460 ? 151.952 110.166 102.041 1.00 48.07  ? 460 ASN A O   1 
ATOM   2992 C  CB  . ASN A 1 460 ? 152.407 110.425 105.296 1.00 48.07  ? 460 ASN A CB  1 
ATOM   2993 C  CG  . ASN A 1 460 ? 153.338 109.340 104.795 1.00 48.07  ? 460 ASN A CG  1 
ATOM   2994 O  OD1 . ASN A 1 460 ? 154.079 109.537 103.832 1.00 48.07  ? 460 ASN A OD1 1 
ATOM   2995 N  ND2 . ASN A 1 460 ? 153.301 108.183 105.445 1.00 48.07  ? 460 ASN A ND2 1 
ATOM   2996 N  N   . LYS A 1 461 ? 150.059 109.891 103.226 1.00 47.98  ? 461 LYS A N   1 
ATOM   2997 C  CA  . LYS A 1 461 ? 149.463 109.043 102.201 1.00 47.98  ? 461 LYS A CA  1 
ATOM   2998 C  C   . LYS A 1 461 ? 149.080 109.824 100.951 1.00 47.98  ? 461 LYS A C   1 
ATOM   2999 O  O   . LYS A 1 461 ? 149.039 109.241 99.863  1.00 47.98  ? 461 LYS A O   1 
ATOM   3000 C  CB  . LYS A 1 461 ? 148.237 108.319 102.758 1.00 47.98  ? 461 LYS A CB  1 
ATOM   3001 C  CG  . LYS A 1 461 ? 148.568 107.132 103.650 1.00 47.98  ? 461 LYS A CG  1 
ATOM   3002 C  CD  . LYS A 1 461 ? 149.671 106.271 103.054 1.00 47.98  ? 461 LYS A CD  1 
ATOM   3003 C  CE  . LYS A 1 461 ? 149.162 105.439 101.888 1.00 47.98  ? 461 LYS A CE  1 
ATOM   3004 N  NZ  . LYS A 1 461 ? 150.272 104.986 101.003 1.00 47.98  ? 461 LYS A NZ  1 
ATOM   3005 N  N   . LEU A 1 462 ? 148.788 111.117 101.080 1.00 49.93  ? 462 LEU A N   1 
ATOM   3006 C  CA  . LEU A 1 462 ? 148.468 111.950 99.927  1.00 49.93  ? 462 LEU A CA  1 
ATOM   3007 C  C   . LEU A 1 462 ? 149.695 112.586 99.289  1.00 49.93  ? 462 LEU A C   1 
ATOM   3008 O  O   . LEU A 1 462 ? 149.573 113.190 98.218  1.00 49.93  ? 462 LEU A O   1 
ATOM   3009 C  CB  . LEU A 1 462 ? 147.478 113.049 100.325 1.00 49.93  ? 462 LEU A CB  1 
ATOM   3010 C  CG  . LEU A 1 462 ? 146.033 112.608 100.558 1.00 49.93  ? 462 LEU A CG  1 
ATOM   3011 C  CD1 . LEU A 1 462 ? 145.106 113.812 100.577 1.00 49.93  ? 462 LEU A CD1 1 
ATOM   3012 C  CD2 . LEU A 1 462 ? 145.598 111.612 99.497  1.00 49.93  ? 462 LEU A CD2 1 
ATOM   3013 N  N   . SER A 1 463 ? 150.861 112.474 99.920  1.00 54.59  ? 463 SER A N   1 
ATOM   3014 C  CA  . SER A 1 463 ? 152.088 113.013 99.337  1.00 54.59  ? 463 SER A CA  1 
ATOM   3015 C  C   . SER A 1 463 ? 152.401 112.524 97.922  1.00 54.59  ? 463 SER A C   1 
ATOM   3016 O  O   . SER A 1 463 ? 152.819 113.358 97.100  1.00 54.59  ? 463 SER A O   1 
ATOM   3017 C  CB  . SER A 1 463 ? 153.271 112.725 100.274 1.00 54.59  ? 463 SER A CB  1 
ATOM   3018 O  OG  . SER A 1 463 ? 153.571 111.342 100.339 1.00 54.59  ? 463 SER A OG  1 
ATOM   3019 N  N   . PRO A 1 464 ? 152.239 111.226 97.554  1.00 59.42  ? 464 PRO A N   1 
ATOM   3020 C  CA  . PRO A 1 464 ? 152.651 110.807 96.203  1.00 59.42  ? 464 PRO A CA  1 
ATOM   3021 C  C   . PRO A 1 464 ? 151.822 111.403 95.073  1.00 59.42  ? 464 PRO A C   1 
ATOM   3022 O  O   . PRO A 1 464 ? 152.010 111.033 93.910  1.00 59.42  ? 464 PRO A O   1 
ATOM   3023 C  CB  . PRO A 1 464 ? 152.508 109.281 96.250  1.00 59.42  ? 464 PRO A CB  1 
ATOM   3024 C  CG  . PRO A 1 464 ? 151.476 109.033 97.263  1.00 59.42  ? 464 PRO A CG  1 
ATOM   3025 C  CD  . PRO A 1 464 ? 151.657 110.097 98.304  1.00 59.42  ? 464 PRO A CD  1 
ATOM   3026 N  N   . LEU A 1 465 ? 150.903 112.317 95.389  1.00 58.11  ? 465 LEU A N   1 
ATOM   3027 C  CA  . LEU A 1 465 ? 150.133 113.007 94.359  1.00 58.11  ? 465 LEU A CA  1 
ATOM   3028 C  C   . LEU A 1 465 ? 150.982 113.925 93.487  1.00 58.11  ? 465 LEU A C   1 
ATOM   3029 O  O   . LEU A 1 465 ? 150.427 114.579 92.597  1.00 58.11  ? 465 LEU A O   1 
ATOM   3030 C  CB  . LEU A 1 465 ? 149.004 113.821 94.996  1.00 58.11  ? 465 LEU A CB  1 
ATOM   3031 C  CG  . LEU A 1 465 ? 147.719 113.081 95.369  1.00 58.11  ? 465 LEU A CG  1 
ATOM   3032 C  CD1 . LEU A 1 465 ? 146.774 114.004 96.120  1.00 58.11  ? 465 LEU A CD1 1 
ATOM   3033 C  CD2 . LEU A 1 465 ? 147.046 112.518 94.132  1.00 58.11  ? 465 LEU A CD2 1 
ATOM   3034 N  N   . GLY A 1 466 ? 152.296 113.994 93.709  1.00 63.46  ? 466 GLY A N   1 
ATOM   3035 C  CA  . GLY A 1 466 ? 153.122 114.921 92.956  1.00 63.46  ? 466 GLY A CA  1 
ATOM   3036 C  C   . GLY A 1 466 ? 153.304 114.537 91.502  1.00 63.46  ? 466 GLY A C   1 
ATOM   3037 O  O   . GLY A 1 466 ? 153.652 115.385 90.674  1.00 63.46  ? 466 GLY A O   1 
ATOM   3038 N  N   . SER A 1 467 ? 153.086 113.263 91.169  1.00 67.12  ? 467 SER A N   1 
ATOM   3039 C  CA  . SER A 1 467 ? 153.231 112.826 89.784  1.00 67.12  ? 467 SER A CA  1 
ATOM   3040 C  C   . SER A 1 467 ? 152.216 113.512 88.878  1.00 67.12  ? 467 SER A C   1 
ATOM   3041 O  O   . SER A 1 467 ? 152.544 113.909 87.754  1.00 67.12  ? 467 SER A O   1 
ATOM   3042 C  CB  . SER A 1 467 ? 153.089 111.307 89.698  1.00 67.12  ? 467 SER A CB  1 
ATOM   3043 O  OG  . SER A 1 467 ? 154.118 110.658 90.425  1.00 67.12  ? 467 SER A OG  1 
ATOM   3044 N  N   . LEU A 1 468 ? 150.980 113.656 89.349  1.00 66.41  ? 468 LEU A N   1 
ATOM   3045 C  CA  . LEU A 1 468 ? 149.936 114.275 88.555  1.00 66.41  ? 468 LEU A CA  1 
ATOM   3046 C  C   . LEU A 1 468 ? 150.181 115.777 88.426  1.00 66.41  ? 468 LEU A C   1 
ATOM   3047 O  O   . LEU A 1 468 ? 150.859 116.379 89.262  1.00 66.41  ? 468 LEU A O   1 
ATOM   3048 C  CB  . LEU A 1 468 ? 148.572 114.006 89.186  1.00 66.41  ? 468 LEU A CB  1 
ATOM   3049 C  CG  . LEU A 1 468 ? 148.221 112.525 89.341  1.00 66.41  ? 468 LEU A CG  1 
ATOM   3050 C  CD1 . LEU A 1 468 ? 147.255 112.315 90.494  1.00 66.41  ? 468 LEU A CD1 1 
ATOM   3051 C  CD2 . LEU A 1 468 ? 147.658 111.954 88.050  1.00 66.41  ? 468 LEU A CD2 1 
ATOM   3052 N  N   . PRO A 1 469 ? 149.646 116.404 87.380  1.00 68.18  ? 469 PRO A N   1 
ATOM   3053 C  CA  . PRO A 1 469 ? 149.856 117.844 87.197  1.00 68.18  ? 469 PRO A CA  1 
ATOM   3054 C  C   . PRO A 1 469 ? 149.185 118.657 88.293  1.00 68.18  ? 469 PRO A C   1 
ATOM   3055 O  O   . PRO A 1 469 ? 148.317 118.178 89.025  1.00 68.18  ? 469 PRO A O   1 
ATOM   3056 C  CB  . PRO A 1 469 ? 149.223 118.133 85.830  1.00 68.18  ? 469 PRO A CB  1 
ATOM   3057 C  CG  . PRO A 1 469 ? 149.128 116.807 85.155  1.00 68.18  ? 469 PRO A CG  1 
ATOM   3058 C  CD  . PRO A 1 469 ? 148.925 115.806 86.244  1.00 68.18  ? 469 PRO A CD  1 
ATOM   3059 N  N   . ALA A 1 470 ? 149.615 119.918 88.396  1.00 64.56  ? 470 ALA A N   1 
ATOM   3060 C  CA  . ALA A 1 470 ? 149.123 120.790 89.458  1.00 64.56  ? 470 ALA A CA  1 
ATOM   3061 C  C   . ALA A 1 470 ? 147.623 121.030 89.339  1.00 64.56  ? 470 ALA A C   1 
ATOM   3062 O  O   . ALA A 1 470 ? 146.911 121.059 90.349  1.00 64.56  ? 470 ALA A O   1 
ATOM   3063 C  CB  . ALA A 1 470 ? 149.881 122.117 89.439  1.00 64.56  ? 470 ALA A CB  1 
ATOM   3064 N  N   . TRP A 1 471 ? 147.126 121.219 88.115  1.00 64.95  ? 471 TRP A N   1 
ATOM   3065 C  CA  . TRP A 1 471 ? 145.695 121.446 87.937  1.00 64.95  ? 471 TRP A CA  1 
ATOM   3066 C  C   . TRP A 1 471 ? 144.888 120.219 88.346  1.00 64.95  ? 471 TRP A C   1 
ATOM   3067 O  O   . TRP A 1 471 ? 143.837 120.344 88.983  1.00 64.95  ? 471 TRP A O   1 
ATOM   3068 C  CB  . TRP A 1 471 ? 145.400 121.847 86.490  1.00 64.95  ? 471 TRP A CB  1 
ATOM   3069 C  CG  . TRP A 1 471 ? 145.709 120.794 85.472  1.00 64.95  ? 471 TRP A CG  1 
ATOM   3070 C  CD1 . TRP A 1 471 ? 146.860 120.664 84.755  1.00 64.95  ? 471 TRP A CD1 1 
ATOM   3071 C  CD2 . TRP A 1 471 ? 144.839 119.745 85.030  1.00 64.95  ? 471 TRP A CD2 1 
ATOM   3072 N  NE1 . TRP A 1 471 ? 146.770 119.587 83.908  1.00 64.95  ? 471 TRP A NE1 1 
ATOM   3073 C  CE2 . TRP A 1 471 ? 145.538 119.007 84.057  1.00 64.95  ? 471 TRP A CE2 1 
ATOM   3074 C  CE3 . TRP A 1 471 ? 143.540 119.354 85.370  1.00 64.95  ? 471 TRP A CE3 1 
ATOM   3075 C  CZ2 . TRP A 1 471 ? 144.983 117.901 83.419  1.00 64.95  ? 471 TRP A CZ2 1 
ATOM   3076 C  CZ3 . TRP A 1 471 ? 142.992 118.255 84.736  1.00 64.95  ? 471 TRP A CZ3 1 
ATOM   3077 C  CH2 . TRP A 1 471 ? 143.712 117.542 83.772  1.00 64.95  ? 471 TRP A CH2 1 
ATOM   3078 N  N   . LEU A 1 472 ? 145.371 119.022 88.010  1.00 63.52  ? 472 LEU A N   1 
ATOM   3079 C  CA  . LEU A 1 472 ? 144.682 117.815 88.452  1.00 63.52  ? 472 LEU A CA  1 
ATOM   3080 C  C   . LEU A 1 472 ? 144.786 117.649 89.963  1.00 63.52  ? 472 LEU A C   1 
ATOM   3081 O  O   . LEU A 1 472 ? 143.842 117.176 90.607  1.00 63.52  ? 472 LEU A O   1 
ATOM   3082 C  CB  . LEU A 1 472 ? 145.243 116.591 87.730  1.00 63.52  ? 472 LEU A CB  1 
ATOM   3083 C  CG  . LEU A 1 472 ? 144.475 115.287 87.950  1.00 63.52  ? 472 LEU A CG  1 
ATOM   3084 C  CD1 . LEU A 1 472 ? 142.991 115.496 87.705  1.00 63.52  ? 472 LEU A CD1 1 
ATOM   3085 C  CD2 . LEU A 1 472 ? 145.009 114.195 87.044  1.00 63.52  ? 472 LEU A CD2 1 
ATOM   3086 N  N   . ILE A 1 473 ? 145.919 118.046 90.545  1.00 60.76  ? 473 ILE A N   1 
ATOM   3087 C  CA  . ILE A 1 473 ? 146.077 117.983 91.996  1.00 60.76  ? 473 ILE A CA  1 
ATOM   3088 C  C   . ILE A 1 473 ? 145.035 118.859 92.678  1.00 60.76  ? 473 ILE A C   1 
ATOM   3089 O  O   . ILE A 1 473 ? 144.351 118.429 93.615  1.00 60.76  ? 473 ILE A O   1 
ATOM   3090 C  CB  . ILE A 1 473 ? 147.504 118.396 92.399  1.00 60.76  ? 473 ILE A CB  1 
ATOM   3091 C  CG1 . ILE A 1 473 ? 148.489 117.256 92.151  1.00 60.76  ? 473 ILE A CG1 1 
ATOM   3092 C  CG2 . ILE A 1 473 ? 147.546 118.820 93.858  1.00 60.76  ? 473 ILE A CG2 1 
ATOM   3093 C  CD1 . ILE A 1 473 ? 149.932 117.705 92.142  1.00 60.76  ? 473 ILE A CD1 1 
ATOM   3094 N  N   . ILE A 1 474 ? 144.897 120.103 92.213  1.00 59.34  ? 474 ILE A N   1 
ATOM   3095 C  CA  . ILE A 1 474 ? 143.935 121.007 92.835  1.00 59.34  ? 474 ILE A CA  1 
ATOM   3096 C  C   . ILE A 1 474 ? 142.505 120.559 92.560  1.00 59.34  ? 474 ILE A C   1 
ATOM   3097 O  O   . ILE A 1 474 ? 141.630 120.721 93.416  1.00 59.34  ? 474 ILE A O   1 
ATOM   3098 C  CB  . ILE A 1 474 ? 144.180 122.465 92.400  1.00 59.34  ? 474 ILE A CB  1 
ATOM   3099 C  CG1 . ILE A 1 474 ? 143.376 123.407 93.290  1.00 59.34  ? 474 ILE A CG1 1 
ATOM   3100 C  CG2 . ILE A 1 474 ? 143.822 122.689 90.946  1.00 59.34  ? 474 ILE A CG2 1 
ATOM   3101 C  CD1 . ILE A 1 474 ? 143.826 123.400 94.717  1.00 59.34  ? 474 ILE A CD1 1 
ATOM   3102 N  N   . LEU A 1 475 ? 142.239 119.982 91.386  1.00 58.08  ? 475 LEU A N   1 
ATOM   3103 C  CA  . LEU A 1 475 ? 140.907 119.451 91.120  1.00 58.08  ? 475 LEU A CA  1 
ATOM   3104 C  C   . LEU A 1 475 ? 140.560 118.339 92.101  1.00 58.08  ? 475 LEU A C   1 
ATOM   3105 O  O   . LEU A 1 475 ? 139.468 118.324 92.682  1.00 58.08  ? 475 LEU A O   1 
ATOM   3106 C  CB  . LEU A 1 475 ? 140.821 118.948 89.680  1.00 58.08  ? 475 LEU A CB  1 
ATOM   3107 C  CG  . LEU A 1 475 ? 139.413 118.676 89.149  1.00 58.08  ? 475 LEU A CG  1 
ATOM   3108 C  CD1 . LEU A 1 475 ? 138.591 119.955 89.133  1.00 58.08  ? 475 LEU A CD1 1 
ATOM   3109 C  CD2 . LEU A 1 475 ? 139.473 118.053 87.764  1.00 58.08  ? 475 LEU A CD2 1 
ATOM   3110 N  N   . ILE A 1 476 ? 141.490 117.405 92.312  1.00 55.19  ? 476 ILE A N   1 
ATOM   3111 C  CA  . ILE A 1 476 ? 141.246 116.306 93.243  1.00 55.19  ? 476 ILE A CA  1 
ATOM   3112 C  C   . ILE A 1 476 ? 141.064 116.836 94.659  1.00 55.19  ? 476 ILE A C   1 
ATOM   3113 O  O   . ILE A 1 476 ? 140.171 116.393 95.393  1.00 55.19  ? 476 ILE A O   1 
ATOM   3114 C  CB  . ILE A 1 476 ? 142.386 115.273 93.163  1.00 55.19  ? 476 ILE A CB  1 
ATOM   3115 C  CG1 . ILE A 1 476 ? 142.316 114.509 91.841  1.00 55.19  ? 476 ILE A CG1 1 
ATOM   3116 C  CG2 . ILE A 1 476 ? 142.321 114.309 94.335  1.00 55.19  ? 476 ILE A CG2 1 
ATOM   3117 C  CD1 . ILE A 1 476 ? 143.518 113.632 91.581  1.00 55.19  ? 476 ILE A CD1 1 
ATOM   3118 N  N   . SER A 1 477 ? 141.902 117.794 95.065  1.00 53.14  ? 477 SER A N   1 
ATOM   3119 C  CA  . SER A 1 477 ? 141.799 118.346 96.412  1.00 53.14  ? 477 SER A CA  1 
ATOM   3120 C  C   . SER A 1 477 ? 140.457 119.038 96.623  1.00 53.14  ? 477 SER A C   1 
ATOM   3121 O  O   . SER A 1 477 ? 139.795 118.835 97.648  1.00 53.14  ? 477 SER A O   1 
ATOM   3122 C  CB  . SER A 1 477 ? 142.950 119.318 96.667  1.00 53.14  ? 477 SER A CB  1 
ATOM   3123 O  OG  . SER A 1 477 ? 144.195 118.728 96.337  1.00 53.14  ? 477 SER A OG  1 
ATOM   3124 N  N   . SER A 1 478 ? 140.036 119.856 95.655  1.00 51.34  ? 478 SER A N   1 
ATOM   3125 C  CA  . SER A 1 478 ? 138.764 120.559 95.779  1.00 51.34  ? 478 SER A CA  1 
ATOM   3126 C  C   . SER A 1 478 ? 137.596 119.584 95.800  1.00 51.34  ? 478 SER A C   1 
ATOM   3127 O  O   . SER A 1 478 ? 136.654 119.753 96.583  1.00 51.34  ? 478 SER A O   1 
ATOM   3128 C  CB  . SER A 1 478 ? 138.605 121.561 94.638  1.00 51.34  ? 478 SER A CB  1 
ATOM   3129 O  OG  . SER A 1 478 ? 139.767 122.360 94.499  1.00 51.34  ? 478 SER A OG  1 
ATOM   3130 N  N   . LEU A 1 479 ? 137.634 118.560 94.942  1.00 49.72  ? 479 LEU A N   1 
ATOM   3131 C  CA  . LEU A 1 479 ? 136.556 117.578 94.930  1.00 49.72  ? 479 LEU A CA  1 
ATOM   3132 C  C   . LEU A 1 479 ? 136.480 116.822 96.249  1.00 49.72  ? 479 LEU A C   1 
ATOM   3133 O  O   . LEU A 1 479 ? 135.388 116.608 96.785  1.00 49.72  ? 479 LEU A O   1 
ATOM   3134 C  CB  . LEU A 1 479 ? 136.732 116.611 93.759  1.00 49.72  ? 479 LEU A CB  1 
ATOM   3135 C  CG  . LEU A 1 479 ? 136.001 116.970 92.462  1.00 49.72  ? 479 LEU A CG  1 
ATOM   3136 C  CD1 . LEU A 1 479 ? 134.497 116.911 92.675  1.00 49.72  ? 479 LEU A CD1 1 
ATOM   3137 C  CD2 . LEU A 1 479 ? 136.406 118.337 91.938  1.00 49.72  ? 479 LEU A CD2 1 
ATOM   3138 N  N   . MET A 1 480 ? 137.629 116.422 96.800  1.00 51.46  ? 480 MET A N   1 
ATOM   3139 C  CA  . MET A 1 480 ? 137.624 115.732 98.086  1.00 51.46  ? 480 MET A CA  1 
ATOM   3140 C  C   . MET A 1 480 ? 137.086 116.630 99.193  1.00 51.46  ? 480 MET A C   1 
ATOM   3141 O  O   . MET A 1 480 ? 136.273 116.194 100.019 1.00 51.46  ? 480 MET A O   1 
ATOM   3142 C  CB  . MET A 1 480 ? 139.032 115.248 98.428  1.00 51.46  ? 480 MET A CB  1 
ATOM   3143 C  CG  . MET A 1 480 ? 139.448 113.983 97.697  1.00 51.46  ? 480 MET A CG  1 
ATOM   3144 S  SD  . MET A 1 480 ? 140.712 113.050 98.580  1.00 51.46  ? 480 MET A SD  1 
ATOM   3145 C  CE  . MET A 1 480 ? 140.689 111.507 97.671  1.00 51.46  ? 480 MET A CE  1 
ATOM   3146 N  N   . VAL A 1 481 ? 137.517 117.894 99.219  1.00 45.37  ? 481 VAL A N   1 
ATOM   3147 C  CA  . VAL A 1 481 ? 137.078 118.807 100.270 1.00 45.37  ? 481 VAL A CA  1 
ATOM   3148 C  C   . VAL A 1 481 ? 135.578 119.055 100.177 1.00 45.37  ? 481 VAL A C   1 
ATOM   3149 O  O   . VAL A 1 481 ? 134.869 119.029 101.190 1.00 45.37  ? 481 VAL A O   1 
ATOM   3150 C  CB  . VAL A 1 481 ? 137.876 120.120 100.205 1.00 45.37  ? 481 VAL A CB  1 
ATOM   3151 C  CG1 . VAL A 1 481 ? 137.219 121.174 101.064 1.00 45.37  ? 481 VAL A CG1 1 
ATOM   3152 C  CG2 . VAL A 1 481 ? 139.306 119.888 100.659 1.00 45.37  ? 481 VAL A CG2 1 
ATOM   3153 N  N   . THR A 1 482 ? 135.066 119.293 98.967  1.00 43.22  ? 482 THR A N   1 
ATOM   3154 C  CA  . THR A 1 482 ? 133.637 119.542 98.817  1.00 43.22  ? 482 THR A CA  1 
ATOM   3155 C  C   . THR A 1 482 ? 132.806 118.277 98.984  1.00 43.22  ? 482 THR A C   1 
ATOM   3156 O  O   . THR A 1 482 ? 131.603 118.375 99.246  1.00 43.22  ? 482 THR A O   1 
ATOM   3157 C  CB  . THR A 1 482 ? 133.341 120.185 97.460  1.00 43.22  ? 482 THR A CB  1 
ATOM   3158 O  OG1 . THR A 1 482 ? 131.997 120.683 97.453  1.00 43.22  ? 482 THR A OG1 1 
ATOM   3159 C  CG2 . THR A 1 482 ? 133.499 119.180 96.336  1.00 43.22  ? 482 THR A CG2 1 
ATOM   3160 N  N   . SER A 1 483 ? 133.408 117.095 98.825  1.00 43.43  ? 483 SER A N   1 
ATOM   3161 C  CA  . SER A 1 483 ? 132.688 115.858 99.097  1.00 43.43  ? 483 SER A CA  1 
ATOM   3162 C  C   . SER A 1 483 ? 132.597 115.579 100.591 1.00 43.43  ? 483 SER A C   1 
ATOM   3163 O  O   . SER A 1 483 ? 131.555 115.126 101.077 1.00 43.43  ? 483 SER A O   1 
ATOM   3164 C  CB  . SER A 1 483 ? 133.363 114.691 98.377  1.00 43.43  ? 483 SER A CB  1 
ATOM   3165 O  OG  . SER A 1 483 ? 133.262 114.833 96.972  1.00 43.43  ? 483 SER A OG  1 
ATOM   3166 N  N   . LEU A 1 484 ? 133.668 115.844 101.335 1.00 38.98  ? 484 LEU A N   1 
ATOM   3167 C  CA  . LEU A 1 484 ? 133.682 115.581 102.767 1.00 38.98  ? 484 LEU A CA  1 
ATOM   3168 C  C   . LEU A 1 484 ? 133.165 116.748 103.597 1.00 38.98  ? 484 LEU A C   1 
ATOM   3169 O  O   . LEU A 1 484 ? 133.148 116.650 104.828 1.00 38.98  ? 484 LEU A O   1 
ATOM   3170 C  CB  . LEU A 1 484 ? 135.095 115.206 103.227 1.00 38.98  ? 484 LEU A CB  1 
ATOM   3171 C  CG  . LEU A 1 484 ? 135.813 114.137 102.400 1.00 38.98  ? 484 LEU A CG  1 
ATOM   3172 C  CD1 . LEU A 1 484 ? 137.167 113.807 103.005 1.00 38.98  ? 484 LEU A CD1 1 
ATOM   3173 C  CD2 . LEU A 1 484 ? 134.960 112.884 102.279 1.00 38.98  ? 484 LEU A CD2 1 
ATOM   3174 N  N   . THR A 1 485 ? 132.752 117.844 102.965 1.00 37.69  ? 485 THR A N   1 
ATOM   3175 C  CA  . THR A 1 485 ? 132.139 118.951 103.685 1.00 37.69  ? 485 THR A CA  1 
ATOM   3176 C  C   . THR A 1 485 ? 130.628 118.813 103.803 1.00 37.69  ? 485 THR A C   1 
ATOM   3177 O  O   . THR A 1 485 ? 130.000 119.629 104.486 1.00 37.69  ? 485 THR A O   1 
ATOM   3178 C  CB  . THR A 1 485 ? 132.470 120.284 103.006 1.00 37.69  ? 485 THR A CB  1 
ATOM   3179 O  OG1 . THR A 1 485 ? 132.167 121.362 103.898 1.00 37.69  ? 485 THR A OG1 1 
ATOM   3180 C  CG2 . THR A 1 485 ? 131.652 120.451 101.742 1.00 37.69  ? 485 THR A CG2 1 
ATOM   3181 N  N   . GLU A 1 486 ? 130.031 117.815 103.150 1.00 37.76  ? 486 GLU A N   1 
ATOM   3182 C  CA  . GLU A 1 486 ? 128.598 117.582 103.289 1.00 37.76  ? 486 GLU A CA  1 
ATOM   3183 C  C   . GLU A 1 486 ? 128.256 116.923 104.617 1.00 37.76  ? 486 GLU A C   1 
ATOM   3184 O  O   . GLU A 1 486 ? 127.106 116.995 105.062 1.00 37.76  ? 486 GLU A O   1 
ATOM   3185 C  CB  . GLU A 1 486 ? 128.087 116.722 102.133 1.00 37.76  ? 486 GLU A CB  1 
ATOM   3186 C  CG  . GLU A 1 486 ? 128.629 117.120 100.773 1.00 37.76  ? 486 GLU A CG  1 
ATOM   3187 C  CD  . GLU A 1 486 ? 128.140 118.480 100.321 1.00 37.76  ? 486 GLU A CD  1 
ATOM   3188 O  OE1 . GLU A 1 486 ? 127.098 118.943 100.830 1.00 37.76  ? 486 GLU A OE1 1 
ATOM   3189 O  OE2 . GLU A 1 486 ? 128.797 119.088 99.451  1.00 37.76  ? 486 GLU A OE2 1 
ATOM   3190 N  N   . VAL A 1 487 ? 129.228 116.281 105.256 1.00 31.32  ? 487 VAL A N   1 
ATOM   3191 C  CA  . VAL A 1 487 ? 128.998 115.637 106.544 1.00 31.32  ? 487 VAL A CA  1 
ATOM   3192 C  C   . VAL A 1 487 ? 129.393 116.543 107.703 1.00 31.32  ? 487 VAL A C   1 
ATOM   3193 O  O   . VAL A 1 487 ? 128.665 116.644 108.692 1.00 31.32  ? 487 VAL A O   1 
ATOM   3194 C  CB  . VAL A 1 487 ? 129.741 114.286 106.596 1.00 31.32  ? 487 VAL A CB  1 
ATOM   3195 C  CG1 . VAL A 1 487 ? 131.220 114.464 106.303 1.00 31.32  ? 487 VAL A CG1 1 
ATOM   3196 C  CG2 . VAL A 1 487 ? 129.562 113.651 107.956 1.00 31.32  ? 487 VAL A CG2 1 
ATOM   3197 N  N   . ALA A 1 488 ? 130.529 117.223 107.603 1.00 33.91  ? 488 ALA A N   1 
ATOM   3198 C  CA  . ALA A 1 488 ? 131.036 118.065 108.672 1.00 33.91  ? 488 ALA A CA  1 
ATOM   3199 C  C   . ALA A 1 488 ? 130.776 119.529 108.353 1.00 33.91  ? 488 ALA A C   1 
ATOM   3200 O  O   . ALA A 1 488 ? 130.635 119.921 107.193 1.00 33.91  ? 488 ALA A O   1 
ATOM   3201 C  CB  . ALA A 1 488 ? 132.534 117.835 108.892 1.00 33.91  ? 488 ALA A CB  1 
ATOM   3202 N  N   . SER A 1 489 ? 130.715 120.337 109.407 1.00 37.85  ? 489 SER A N   1 
ATOM   3203 C  CA  . SER A 1 489 ? 130.513 121.766 109.235 1.00 37.85  ? 489 SER A CA  1 
ATOM   3204 C  C   . SER A 1 489 ? 131.711 122.382 108.521 1.00 37.85  ? 489 SER A C   1 
ATOM   3205 O  O   . SER A 1 489 ? 132.822 121.847 108.551 1.00 37.85  ? 489 SER A O   1 
ATOM   3206 C  CB  . SER A 1 489 ? 130.295 122.437 110.590 1.00 37.85  ? 489 SER A CB  1 
ATOM   3207 O  OG  . SER A 1 489 ? 129.827 123.763 110.430 1.00 37.85  ? 489 SER A OG  1 
ATOM   3208 N  N   . ASN A 1 490 ? 131.469 123.511 107.855 1.00 39.91  ? 490 ASN A N   1 
ATOM   3209 C  CA  . ASN A 1 490 ? 132.537 124.170 107.105 1.00 39.91  ? 490 ASN A CA  1 
ATOM   3210 C  C   . ASN A 1 490 ? 133.735 124.543 107.971 1.00 39.91  ? 490 ASN A C   1 
ATOM   3211 O  O   . ASN A 1 490 ? 134.873 124.249 107.564 1.00 39.91  ? 490 ASN A O   1 
ATOM   3212 C  CB  . ASN A 1 490 ? 131.974 125.395 106.378 1.00 39.91  ? 490 ASN A CB  1 
ATOM   3213 C  CG  . ASN A 1 490 ? 130.823 125.050 105.460 1.00 39.91  ? 490 ASN A CG  1 
ATOM   3214 O  OD1 . ASN A 1 490 ? 130.805 123.986 104.845 1.00 39.91  ? 490 ASN A OD1 1 
ATOM   3215 N  ND2 . ASN A 1 490 ? 129.855 125.952 105.361 1.00 39.91  ? 490 ASN A ND2 1 
ATOM   3216 N  N   . PRO A 1 491 ? 133.576 125.188 109.138 1.00 38.45  ? 491 PRO A N   1 
ATOM   3217 C  CA  . PRO A 1 491 ? 134.766 125.472 109.959 1.00 38.45  ? 491 PRO A CA  1 
ATOM   3218 C  C   . PRO A 1 491 ? 135.503 124.220 110.395 1.00 38.45  ? 491 PRO A C   1 
ATOM   3219 O  O   . PRO A 1 491 ? 136.739 124.193 110.375 1.00 38.45  ? 491 PRO A O   1 
ATOM   3220 C  CB  . PRO A 1 491 ? 134.191 126.239 111.159 1.00 38.45  ? 491 PRO A CB  1 
ATOM   3221 C  CG  . PRO A 1 491 ? 132.874 126.734 110.711 1.00 38.45  ? 491 PRO A CG  1 
ATOM   3222 C  CD  . PRO A 1 491 ? 132.352 125.713 109.767 1.00 38.45  ? 491 PRO A CD  1 
ATOM   3223 N  N   . ALA A 1 492 ? 134.771 123.171 110.778 1.00 34.72  ? 492 ALA A N   1 
ATOM   3224 C  CA  . ALA A 1 492 ? 135.418 121.927 111.176 1.00 34.72  ? 492 ALA A CA  1 
ATOM   3225 C  C   . ALA A 1 492 ? 136.186 121.312 110.015 1.00 34.72  ? 492 ALA A C   1 
ATOM   3226 O  O   . ALA A 1 492 ? 137.331 120.876 110.179 1.00 34.72  ? 492 ALA A O   1 
ATOM   3227 C  CB  . ALA A 1 492 ? 134.379 120.945 111.714 1.00 34.72  ? 492 ALA A CB  1 
ATOM   3228 N  N   . THR A 1 493 ? 135.578 121.284 108.828 1.00 38.30  ? 493 THR A N   1 
ATOM   3229 C  CA  . THR A 1 493 ? 136.250 120.710 107.669 1.00 38.30  ? 493 THR A CA  1 
ATOM   3230 C  C   . THR A 1 493 ? 137.505 121.495 107.311 1.00 38.30  ? 493 THR A C   1 
ATOM   3231 O  O   . THR A 1 493 ? 138.554 120.905 107.021 1.00 38.30  ? 493 THR A O   1 
ATOM   3232 C  CB  . THR A 1 493 ? 135.296 120.660 106.477 1.00 38.30  ? 493 THR A CB  1 
ATOM   3233 O  OG1 . THR A 1 493 ? 134.097 119.973 106.852 1.00 38.30  ? 493 THR A OG1 1 
ATOM   3234 C  CG2 . THR A 1 493 ? 135.942 119.931 105.311 1.00 38.30  ? 493 THR A CG2 1 
ATOM   3235 N  N   . ILE A 1 494 ? 137.427 122.828 107.336 1.00 42.68  ? 494 ILE A N   1 
ATOM   3236 C  CA  . ILE A 1 494 ? 138.587 123.618 106.937 1.00 42.68  ? 494 ILE A CA  1 
ATOM   3237 C  C   . ILE A 1 494 ? 139.699 123.507 107.974 1.00 42.68  ? 494 ILE A C   1 
ATOM   3238 O  O   . ILE A 1 494 ? 140.878 123.386 107.618 1.00 42.68  ? 494 ILE A O   1 
ATOM   3239 C  CB  . ILE A 1 494 ? 138.191 125.082 106.658 1.00 42.68  ? 494 ILE A CB  1 
ATOM   3240 C  CG1 . ILE A 1 494 ? 139.338 125.811 105.956 1.00 42.68  ? 494 ILE A CG1 1 
ATOM   3241 C  CG2 . ILE A 1 494 ? 137.800 125.818 107.926 1.00 42.68  ? 494 ILE A CG2 1 
ATOM   3242 C  CD1 . ILE A 1 494 ? 139.694 125.229 104.608 1.00 42.68  ? 494 ILE A CD1 1 
ATOM   3243 N  N   . THR A 1 495 ? 139.356 123.523 109.267 1.00 39.02  ? 495 THR A N   1 
ATOM   3244 C  CA  . THR A 1 495 ? 140.394 123.393 110.281 1.00 39.02  ? 495 THR A CA  1 
ATOM   3245 C  C   . THR A 1 495 ? 140.973 121.988 110.322 1.00 39.02  ? 495 THR A C   1 
ATOM   3246 O  O   . THR A 1 495 ? 142.112 121.816 110.763 1.00 39.02  ? 495 THR A O   1 
ATOM   3247 C  CB  . THR A 1 495 ? 139.862 123.785 111.663 1.00 39.02  ? 495 THR A CB  1 
ATOM   3248 O  OG1 . THR A 1 495 ? 140.959 123.925 112.573 1.00 39.02  ? 495 THR A OG1 1 
ATOM   3249 C  CG2 . THR A 1 495 ? 138.917 122.732 112.205 1.00 39.02  ? 495 THR A CG2 1 
ATOM   3250 N  N   . LEU A 1 496 ? 140.221 120.984 109.864 1.00 38.83  ? 496 LEU A N   1 
ATOM   3251 C  CA  . LEU A 1 496 ? 140.770 119.641 109.741 1.00 38.83  ? 496 LEU A CA  1 
ATOM   3252 C  C   . LEU A 1 496 ? 141.706 119.527 108.545 1.00 38.83  ? 496 LEU A C   1 
ATOM   3253 O  O   . LEU A 1 496 ? 142.761 118.891 108.640 1.00 38.83  ? 496 LEU A O   1 
ATOM   3254 C  CB  . LEU A 1 496 ? 139.634 118.624 109.628 1.00 38.83  ? 496 LEU A CB  1 
ATOM   3255 C  CG  . LEU A 1 496 ? 139.970 117.230 109.098 1.00 38.83  ? 496 LEU A CG  1 
ATOM   3256 C  CD1 . LEU A 1 496 ? 140.941 116.515 110.019 1.00 38.83  ? 496 LEU A CD1 1 
ATOM   3257 C  CD2 . LEU A 1 496 ? 138.702 116.411 108.911 1.00 38.83  ? 496 LEU A CD2 1 
ATOM   3258 N  N   . PHE A 1 497 ? 141.344 120.141 107.418 1.00 43.64  ? 497 PHE A N   1 
ATOM   3259 C  CA  . PHE A 1 497 ? 142.083 119.927 106.182 1.00 43.64  ? 497 PHE A CA  1 
ATOM   3260 C  C   . PHE A 1 497 ? 143.252 120.881 105.986 1.00 43.64  ? 497 PHE A C   1 
ATOM   3261 O  O   . PHE A 1 497 ? 144.134 120.586 105.172 1.00 43.64  ? 497 PHE A O   1 
ATOM   3262 C  CB  . PHE A 1 497 ? 141.140 120.033 104.981 1.00 43.64  ? 497 PHE A CB  1 
ATOM   3263 C  CG  . PHE A 1 497 ? 140.639 118.707 104.494 1.00 43.64  ? 497 PHE A CG  1 
ATOM   3264 C  CD1 . PHE A 1 497 ? 141.494 117.821 103.862 1.00 43.64  ? 497 PHE A CD1 1 
ATOM   3265 C  CD2 . PHE A 1 497 ? 139.318 118.340 104.681 1.00 43.64  ? 497 PHE A CD2 1 
ATOM   3266 C  CE1 . PHE A 1 497 ? 141.039 116.599 103.419 1.00 43.64  ? 497 PHE A CE1 1 
ATOM   3267 C  CE2 . PHE A 1 497 ? 138.857 117.118 104.241 1.00 43.64  ? 497 PHE A CE2 1 
ATOM   3268 C  CZ  . PHE A 1 497 ? 139.719 116.246 103.609 1.00 43.64  ? 497 PHE A CZ  1 
ATOM   3269 N  N   . LEU A 1 498 ? 143.288 122.011 106.693 1.00 48.25  ? 498 LEU A N   1 
ATOM   3270 C  CA  . LEU A 1 498 ? 144.425 122.918 106.541 1.00 48.25  ? 498 LEU A CA  1 
ATOM   3271 C  C   . LEU A 1 498 ? 145.745 122.279 106.957 1.00 48.25  ? 498 LEU A C   1 
ATOM   3272 O  O   . LEU A 1 498 ? 146.708 122.344 106.172 1.00 48.25  ? 498 LEU A O   1 
ATOM   3273 C  CB  . LEU A 1 498 ? 144.157 124.218 107.307 1.00 48.25  ? 498 LEU A CB  1 
ATOM   3274 C  CG  . LEU A 1 498 ? 143.242 125.242 106.635 1.00 48.25  ? 498 LEU A CG  1 
ATOM   3275 C  CD1 . LEU A 1 498 ? 142.717 126.233 107.659 1.00 48.25  ? 498 LEU A CD1 1 
ATOM   3276 C  CD2 . LEU A 1 498 ? 143.964 125.960 105.511 1.00 48.25  ? 498 LEU A CD2 1 
ATOM   3277 N  N   . PRO A 1 499 ? 145.871 121.648 108.133 1.00 48.10  ? 499 PRO A N   1 
ATOM   3278 C  CA  . PRO A 1 499 ? 147.148 121.000 108.474 1.00 48.10  ? 499 PRO A CA  1 
ATOM   3279 C  C   . PRO A 1 499 ? 147.498 119.830 107.575 1.00 48.10  ? 499 PRO A C   1 
ATOM   3280 O  O   . PRO A 1 499 ? 148.650 119.383 107.590 1.00 48.10  ? 499 PRO A O   1 
ATOM   3281 C  CB  . PRO A 1 499 ? 146.938 120.544 109.925 1.00 48.10  ? 499 PRO A CB  1 
ATOM   3282 C  CG  . PRO A 1 499 ? 145.837 121.398 110.437 1.00 48.10  ? 499 PRO A CG  1 
ATOM   3283 C  CD  . PRO A 1 499 ? 144.931 121.590 109.266 1.00 48.10  ? 499 PRO A CD  1 
ATOM   3284 N  N   . ILE A 1 500 ? 146.543 119.300 106.818 1.00 45.35  ? 500 ILE A N   1 
ATOM   3285 C  CA  . ILE A 1 500 ? 146.833 118.239 105.859 1.00 45.35  ? 500 ILE A CA  1 
ATOM   3286 C  C   . ILE A 1 500 ? 147.258 118.811 104.516 1.00 45.35  ? 500 ILE A C   1 
ATOM   3287 O  O   . ILE A 1 500 ? 148.225 118.349 103.906 1.00 45.35  ? 500 ILE A O   1 
ATOM   3288 C  CB  . ILE A 1 500 ? 145.607 117.314 105.708 1.00 45.35  ? 500 ILE A CB  1 
ATOM   3289 C  CG1 . ILE A 1 500 ? 145.148 116.806 107.074 1.00 45.35  ? 500 ILE A CG1 1 
ATOM   3290 C  CG2 . ILE A 1 500 ? 145.927 116.157 104.778 1.00 45.35  ? 500 ILE A CG2 1 
ATOM   3291 C  CD1 . ILE A 1 500 ? 143.755 116.220 107.067 1.00 45.35  ? 500 ILE A CD1 1 
ATOM   3292 N  N   . LEU A 1 501 ? 146.538 119.826 104.036 1.00 51.09  ? 501 LEU A N   1 
ATOM   3293 C  CA  . LEU A 1 501 ? 146.794 120.360 102.704 1.00 51.09  ? 501 LEU A CA  1 
ATOM   3294 C  C   . LEU A 1 501 ? 148.032 121.247 102.662 1.00 51.09  ? 501 LEU A C   1 
ATOM   3295 O  O   . LEU A 1 501 ? 148.775 121.222 101.675 1.00 51.09  ? 501 LEU A O   1 
ATOM   3296 C  CB  . LEU A 1 501 ? 145.572 121.132 102.210 1.00 51.09  ? 501 LEU A CB  1 
ATOM   3297 C  CG  . LEU A 1 501 ? 144.361 120.265 101.872 1.00 51.09  ? 501 LEU A CG  1 
ATOM   3298 C  CD1 . LEU A 1 501 ? 143.227 121.120 101.350 1.00 51.09  ? 501 LEU A CD1 1 
ATOM   3299 C  CD2 . LEU A 1 501 ? 144.741 119.198 100.860 1.00 51.09  ? 501 LEU A CD2 1 
ATOM   3300 N  N   . SER A 1 502 ? 148.269 122.042 103.708 1.00 59.00  ? 502 SER A N   1 
ATOM   3301 C  CA  . SER A 1 502 ? 149.372 123.000 103.654 1.00 59.00  ? 502 SER A CA  1 
ATOM   3302 C  C   . SER A 1 502 ? 150.736 122.333 103.505 1.00 59.00  ? 502 SER A C   1 
ATOM   3303 O  O   . SER A 1 502 ? 151.521 122.782 102.651 1.00 59.00  ? 502 SER A O   1 
ATOM   3304 C  CB  . SER A 1 502 ? 149.318 123.923 104.876 1.00 59.00  ? 502 SER A CB  1 
ATOM   3305 O  OG  . SER A 1 502 ? 150.342 124.898 104.812 1.00 59.00  ? 502 SER A OG  1 
ATOM   3306 N  N   . PRO A 1 503 ? 151.097 121.297 104.275 1.00 60.68  ? 503 PRO A N   1 
ATOM   3307 C  CA  . PRO A 1 503 ? 152.358 120.594 103.975 1.00 60.68  ? 503 PRO A CA  1 
ATOM   3308 C  C   . PRO A 1 503 ? 152.383 119.972 102.592 1.00 60.68  ? 503 PRO A C   1 
ATOM   3309 O  O   . PRO A 1 503 ? 153.455 119.889 101.979 1.00 60.68  ? 503 PRO A O   1 
ATOM   3310 C  CB  . PRO A 1 503 ? 152.454 119.516 105.065 1.00 60.68  ? 503 PRO A CB  1 
ATOM   3311 C  CG  . PRO A 1 503 ? 151.404 119.792 106.039 1.00 60.68  ? 503 PRO A CG  1 
ATOM   3312 C  CD  . PRO A 1 503 ? 150.503 120.870 105.554 1.00 60.68  ? 503 PRO A CD  1 
ATOM   3313 N  N   . LEU A 1 504 ? 151.232 119.522 102.086 1.00 63.57  ? 504 LEU A N   1 
ATOM   3314 C  CA  . LEU A 1 504 ? 151.195 118.906 100.764 1.00 63.57  ? 504 LEU A CA  1 
ATOM   3315 C  C   . LEU A 1 504 ? 151.612 119.894 99.684  1.00 63.57  ? 504 LEU A C   1 
ATOM   3316 O  O   . LEU A 1 504 ? 152.354 119.538 98.762  1.00 63.57  ? 504 LEU A O   1 
ATOM   3317 C  CB  . LEU A 1 504 ? 149.798 118.359 100.476 1.00 63.57  ? 504 LEU A CB  1 
ATOM   3318 C  CG  . LEU A 1 504 ? 149.637 117.626 99.144  1.00 63.57  ? 504 LEU A CG  1 
ATOM   3319 C  CD1 . LEU A 1 504 ? 150.521 116.392 99.107  1.00 63.57  ? 504 LEU A CD1 1 
ATOM   3320 C  CD2 . LEU A 1 504 ? 148.184 117.257 98.902  1.00 63.57  ? 504 LEU A CD2 1 
ATOM   3321 N  N   . ALA A 1 505 ? 151.150 121.142 99.785  1.00 68.94  ? 505 ALA A N   1 
ATOM   3322 C  CA  . ALA A 1 505 ? 151.535 122.153 98.806  1.00 68.94  ? 505 ALA A CA  1 
ATOM   3323 C  C   . ALA A 1 505 ? 153.040 122.385 98.822  1.00 68.94  ? 505 ALA A C   1 
ATOM   3324 O  O   . ALA A 1 505 ? 153.666 122.529 97.765  1.00 68.94  ? 505 ALA A O   1 
ATOM   3325 C  CB  . ALA A 1 505 ? 150.785 123.455 99.077  1.00 68.94  ? 505 ALA A CB  1 
ATOM   3326 N  N   . GLU A 1 506 ? 153.638 122.422 100.013 1.00 73.87  ? 506 GLU A N   1 
ATOM   3327 C  CA  . GLU A 1 506 ? 155.083 122.588 100.112 1.00 73.87  ? 506 GLU A CA  1 
ATOM   3328 C  C   . GLU A 1 506 ? 155.826 121.385 99.548  1.00 73.87  ? 506 GLU A C   1 
ATOM   3329 O  O   . GLU A 1 506 ? 156.897 121.543 98.952  1.00 73.87  ? 506 GLU A O   1 
ATOM   3330 C  CB  . GLU A 1 506 ? 155.477 122.818 101.569 1.00 73.87  ? 506 GLU A CB  1 
ATOM   3331 C  CG  . GLU A 1 506 ? 154.970 124.127 102.146 1.00 73.87  ? 506 GLU A CG  1 
ATOM   3332 C  CD  . GLU A 1 506 ? 155.354 124.307 103.600 1.00 73.87  ? 506 GLU A CD  1 
ATOM   3333 O  OE1 . GLU A 1 506 ? 155.912 123.359 104.191 1.00 73.87  ? 506 GLU A OE1 1 
ATOM   3334 O  OE2 . GLU A 1 506 ? 155.093 125.395 104.155 1.00 73.87  ? 506 GLU A OE2 1 
ATOM   3335 N  N   . ALA A 1 507 ? 155.277 120.181 99.729  1.00 76.25  ? 507 ALA A N   1 
ATOM   3336 C  CA  . ALA A 1 507 ? 155.969 118.972 99.288  1.00 76.25  ? 507 ALA A CA  1 
ATOM   3337 C  C   . ALA A 1 507 ? 156.093 118.913 97.770  1.00 76.25  ? 507 ALA A C   1 
ATOM   3338 O  O   . ALA A 1 507 ? 157.134 118.503 97.242  1.00 76.25  ? 507 ALA A O   1 
ATOM   3339 C  CB  . ALA A 1 507 ? 155.245 117.734 99.815  1.00 76.25  ? 507 ALA A CB  1 
ATOM   3340 N  N   . ILE A 1 508 ? 155.048 119.317 97.049  1.00 76.80  ? 508 ILE A N   1 
ATOM   3341 C  CA  . ILE A 1 508 ? 155.023 119.189 95.595  1.00 76.80  ? 508 ILE A CA  1 
ATOM   3342 C  C   . ILE A 1 508 ? 155.709 120.393 94.959  1.00 76.80  ? 508 ILE A C   1 
ATOM   3343 O  O   . ILE A 1 508 ? 155.697 120.553 93.733  1.00 76.80  ? 508 ILE A O   1 
ATOM   3344 C  CB  . ILE A 1 508 ? 153.580 119.029 95.077  1.00 76.80  ? 508 ILE A CB  1 
ATOM   3345 C  CG1 . ILE A 1 508 ? 152.760 118.164 96.034  1.00 76.80  ? 508 ILE A CG1 1 
ATOM   3346 C  CG2 . ILE A 1 508 ? 153.562 118.393 93.696  1.00 76.80  ? 508 ILE A CG2 1 
ATOM   3347 C  CD1 . ILE A 1 508 ? 153.235 116.729 96.124  1.00 76.80  ? 508 ILE A CD1 1 
ATOM   3348 N  N   . HIS A 1 509 ? 156.325 121.238 95.788  1.00 82.09  ? 509 HIS A N   1 
ATOM   3349 C  CA  . HIS A 1 509 ? 157.042 122.424 95.319  1.00 82.09  ? 509 HIS A CA  1 
ATOM   3350 C  C   . HIS A 1 509 ? 156.126 123.326 94.492  1.00 82.09  ? 509 HIS A C   1 
ATOM   3351 O  O   . HIS A 1 509 ? 156.469 123.766 93.393  1.00 82.09  ? 509 HIS A O   1 
ATOM   3352 C  CB  . HIS A 1 509 ? 158.294 122.032 94.528  1.00 82.09  ? 509 HIS A CB  1 
ATOM   3353 C  CG  . HIS A 1 509 ? 159.337 123.104 94.473  1.00 82.09  ? 509 HIS A CG  1 
ATOM   3354 N  ND1 . HIS A 1 509 ? 159.740 123.809 95.587  1.00 82.09  ? 509 HIS A ND1 1 
ATOM   3355 C  CD2 . HIS A 1 509 ? 160.062 123.590 93.438  1.00 82.09  ? 509 HIS A CD2 1 
ATOM   3356 C  CE1 . HIS A 1 509 ? 160.666 124.684 95.240  1.00 82.09  ? 509 HIS A CE1 1 
ATOM   3357 N  NE2 . HIS A 1 509 ? 160.880 124.572 93.941  1.00 82.09  ? 509 HIS A NE2 1 
ATOM   3358 N  N   . VAL A 1 510 ? 154.943 123.598 95.037  1.00 75.14  ? 510 VAL A N   1 
ATOM   3359 C  CA  . VAL A 1 510 ? 153.943 124.431 94.385  1.00 75.14  ? 510 VAL A CA  1 
ATOM   3360 C  C   . VAL A 1 510 ? 153.542 125.530 95.358  1.00 75.14  ? 510 VAL A C   1 
ATOM   3361 O  O   . VAL A 1 510 ? 153.734 125.408 96.572  1.00 75.14  ? 510 VAL A O   1 
ATOM   3362 C  CB  . VAL A 1 510 ? 152.714 123.603 93.937  1.00 75.14  ? 510 VAL A CB  1 
ATOM   3363 C  CG1 . VAL A 1 510 ? 151.906 123.143 95.140  1.00 75.14  ? 510 VAL A CG1 1 
ATOM   3364 C  CG2 . VAL A 1 510 ? 151.849 124.381 92.951  1.00 75.14  ? 510 VAL A CG2 1 
ATOM   3365 N  N   . ASN A 1 511 ? 153.004 126.618 94.816  1.00 73.78  ? 511 ASN A N   1 
ATOM   3366 C  CA  . ASN A 1 511 ? 152.604 127.744 95.646  1.00 73.78  ? 511 ASN A CA  1 
ATOM   3367 C  C   . ASN A 1 511 ? 151.542 127.297 96.646  1.00 73.78  ? 511 ASN A C   1 
ATOM   3368 O  O   . ASN A 1 511 ? 150.521 126.724 96.243  1.00 73.78  ? 511 ASN A O   1 
ATOM   3369 C  CB  . ASN A 1 511 ? 152.068 128.880 94.776  1.00 73.78  ? 511 ASN A CB  1 
ATOM   3370 C  CG  . ASN A 1 511 ? 152.049 130.211 95.499  1.00 73.78  ? 511 ASN A CG  1 
ATOM   3371 O  OD1 . ASN A 1 511 ? 151.602 130.306 96.641  1.00 73.78  ? 511 ASN A OD1 1 
ATOM   3372 N  ND2 . ASN A 1 511 ? 152.534 131.252 94.832  1.00 73.78  ? 511 ASN A ND2 1 
ATOM   3373 N  N   . PRO A 1 512 ? 151.750 127.519 97.948  1.00 71.76  ? 512 PRO A N   1 
ATOM   3374 C  CA  . PRO A 1 512 ? 150.747 127.076 98.931  1.00 71.76  ? 512 PRO A CA  1 
ATOM   3375 C  C   . PRO A 1 512 ? 149.379 127.699 98.724  1.00 71.76  ? 512 PRO A C   1 
ATOM   3376 O  O   . PRO A 1 512 ? 148.360 127.044 98.974  1.00 71.76  ? 512 PRO A O   1 
ATOM   3377 C  CB  . PRO A 1 512 ? 151.370 127.497 100.269 1.00 71.76  ? 512 PRO A CB  1 
ATOM   3378 C  CG  . PRO A 1 512 ? 152.836 127.523 100.001 1.00 71.76  ? 512 PRO A CG  1 
ATOM   3379 C  CD  . PRO A 1 512 ? 152.968 128.031 98.595  1.00 71.76  ? 512 PRO A CD  1 
ATOM   3380 N  N   . LEU A 1 513 ? 149.327 128.954 98.274  1.00 67.35  ? 513 LEU A N   1 
ATOM   3381 C  CA  . LEU A 1 513 ? 148.039 129.596 98.045  1.00 67.35  ? 513 LEU A CA  1 
ATOM   3382 C  C   . LEU A 1 513 ? 147.277 128.907 96.920  1.00 67.35  ? 513 LEU A C   1 
ATOM   3383 O  O   . LEU A 1 513 ? 146.051 128.767 96.991  1.00 67.35  ? 513 LEU A O   1 
ATOM   3384 C  CB  . LEU A 1 513 ? 148.238 131.080 97.743  1.00 67.35  ? 513 LEU A CB  1 
ATOM   3385 C  CG  . LEU A 1 513 ? 148.263 132.005 98.963  1.00 67.35  ? 513 LEU A CG  1 
ATOM   3386 C  CD1 . LEU A 1 513 ? 148.390 133.459 98.540  1.00 67.35  ? 513 LEU A CD1 1 
ATOM   3387 C  CD2 . LEU A 1 513 ? 147.029 131.801 99.825  1.00 67.35  ? 513 LEU A CD2 1 
ATOM   3388 N  N   . TYR A 1 514 ? 147.993 128.439 95.891  1.00 65.52  ? 514 TYR A N   1 
ATOM   3389 C  CA  . TYR A 1 514 ? 147.351 127.748 94.774  1.00 65.52  ? 514 TYR A CA  1 
ATOM   3390 C  C   . TYR A 1 514 ? 146.553 126.535 95.228  1.00 65.52  ? 514 TYR A C   1 
ATOM   3391 O  O   . TYR A 1 514 ? 145.611 126.125 94.542  1.00 65.52  ? 514 TYR A O   1 
ATOM   3392 C  CB  . TYR A 1 514 ? 148.400 127.322 93.747  1.00 65.52  ? 514 TYR A CB  1 
ATOM   3393 C  CG  . TYR A 1 514 ? 147.846 127.079 92.361  1.00 65.52  ? 514 TYR A CG  1 
ATOM   3394 C  CD1 . TYR A 1 514 ? 147.391 128.127 91.578  1.00 65.52  ? 514 TYR A CD1 1 
ATOM   3395 C  CD2 . TYR A 1 514 ? 147.788 125.796 91.835  1.00 65.52  ? 514 TYR A CD2 1 
ATOM   3396 C  CE1 . TYR A 1 514 ? 146.889 127.907 90.311  1.00 65.52  ? 514 TYR A CE1 1 
ATOM   3397 C  CE2 . TYR A 1 514 ? 147.288 125.565 90.569  1.00 65.52  ? 514 TYR A CE2 1 
ATOM   3398 C  CZ  . TYR A 1 514 ? 146.839 126.625 89.811  1.00 65.52  ? 514 TYR A CZ  1 
ATOM   3399 O  OH  . TYR A 1 514 ? 146.339 126.403 88.548  1.00 65.52  ? 514 TYR A OH  1 
ATOM   3400 N  N   . ILE A 1 515 ? 146.913 125.941 96.361  1.00 60.10  ? 515 ILE A N   1 
ATOM   3401 C  CA  . ILE A 1 515 ? 146.184 124.804 96.902  1.00 60.10  ? 515 ILE A CA  1 
ATOM   3402 C  C   . ILE A 1 515 ? 145.201 125.231 97.984  1.00 60.10  ? 515 ILE A C   1 
ATOM   3403 O  O   . ILE A 1 515 ? 144.100 124.688 98.073  1.00 60.10  ? 515 ILE A O   1 
ATOM   3404 C  CB  . ILE A 1 515 ? 147.168 123.739 97.432  1.00 60.10  ? 515 ILE A CB  1 
ATOM   3405 C  CG1 . ILE A 1 515 ? 148.228 123.429 96.376  1.00 60.10  ? 515 ILE A CG1 1 
ATOM   3406 C  CG2 . ILE A 1 515 ? 146.426 122.472 97.819  1.00 60.10  ? 515 ILE A CG2 1 
ATOM   3407 C  CD1 . ILE A 1 515 ? 147.658 122.885 95.087  1.00 60.10  ? 515 ILE A CD1 1 
ATOM   3408 N  N   . LEU A 1 516 ? 145.581 126.208 98.807  1.00 58.46  ? 516 LEU A N   1 
ATOM   3409 C  CA  . LEU A 1 516 ? 144.748 126.585 99.942  1.00 58.46  ? 516 LEU A CA  1 
ATOM   3410 C  C   . LEU A 1 516 ? 143.518 127.382 99.519  1.00 58.46  ? 516 LEU A C   1 
ATOM   3411 O  O   . LEU A 1 516 ? 142.424 127.155 100.048 1.00 58.46  ? 516 LEU A O   1 
ATOM   3412 C  CB  . LEU A 1 516 ? 145.575 127.374 100.954 1.00 58.46  ? 516 LEU A CB  1 
ATOM   3413 C  CG  . LEU A 1 516 ? 146.660 126.572 101.673 1.00 58.46  ? 516 LEU A CG  1 
ATOM   3414 C  CD1 . LEU A 1 516 ? 147.576 127.492 102.465 1.00 58.46  ? 516 LEU A CD1 1 
ATOM   3415 C  CD2 . LEU A 1 516 ? 146.036 125.521 102.572 1.00 58.46  ? 516 LEU A CD2 1 
ATOM   3416 N  N   . ILE A 1 517 ? 143.669 128.325 98.583  1.00 57.27  ? 517 ILE A N   1 
ATOM   3417 C  CA  . ILE A 1 517 ? 142.534 129.160 98.186  1.00 57.27  ? 517 ILE A CA  1 
ATOM   3418 C  C   . ILE A 1 517 ? 141.404 128.345 97.568  1.00 57.27  ? 517 ILE A C   1 
ATOM   3419 O  O   . ILE A 1 517 ? 140.258 128.479 98.025  1.00 57.27  ? 517 ILE A O   1 
ATOM   3420 C  CB  . ILE A 1 517 ? 143.011 130.300 97.268  1.00 57.27  ? 517 ILE A CB  1 
ATOM   3421 C  CG1 . ILE A 1 517 ? 143.976 131.221 98.011  1.00 57.27  ? 517 ILE A CG1 1 
ATOM   3422 C  CG2 . ILE A 1 517 ? 141.826 131.086 96.736  1.00 57.27  ? 517 ILE A CG2 1 
ATOM   3423 C  CD1 . ILE A 1 517 ? 144.551 132.316 97.144  1.00 57.27  ? 517 ILE A CD1 1 
ATOM   3424 N  N   . PRO A 1 518 ? 141.634 127.502 96.550  1.00 53.71  ? 518 PRO A N   1 
ATOM   3425 C  CA  . PRO A 1 518 ? 140.507 126.722 96.012  1.00 53.71  ? 518 PRO A CA  1 
ATOM   3426 C  C   . PRO A 1 518 ? 139.871 125.808 97.040  1.00 53.71  ? 518 PRO A C   1 
ATOM   3427 O  O   . PRO A 1 518 ? 138.645 125.652 97.049  1.00 53.71  ? 518 PRO A O   1 
ATOM   3428 C  CB  . PRO A 1 518 ? 141.144 125.932 94.860  1.00 53.71  ? 518 PRO A CB  1 
ATOM   3429 C  CG  . PRO A 1 518 ? 142.377 126.678 94.521  1.00 53.71  ? 518 PRO A CG  1 
ATOM   3430 C  CD  . PRO A 1 518 ? 142.877 127.219 95.814  1.00 53.71  ? 518 PRO A CD  1 
ATOM   3431 N  N   . SER A 1 519 ? 140.673 125.211 97.923  1.00 53.35  ? 519 SER A N   1 
ATOM   3432 C  CA  . SER A 1 519 ? 140.117 124.350 98.960  1.00 53.35  ? 519 SER A CA  1 
ATOM   3433 C  C   . SER A 1 519 ? 139.257 125.142 99.935  1.00 53.35  ? 519 SER A C   1 
ATOM   3434 O  O   . SER A 1 519 ? 138.186 124.682 100.344 1.00 53.35  ? 519 SER A O   1 
ATOM   3435 C  CB  . SER A 1 519 ? 141.243 123.631 99.700  1.00 53.35  ? 519 SER A CB  1 
ATOM   3436 O  OG  . SER A 1 519 ? 141.944 122.762 98.829  1.00 53.35  ? 519 SER A OG  1 
ATOM   3437 N  N   . THR A 1 520 ? 139.711 126.336 100.323 1.00 51.12  ? 520 THR A N   1 
ATOM   3438 C  CA  . THR A 1 520 ? 138.921 127.169 101.223 1.00 51.12  ? 520 THR A CA  1 
ATOM   3439 C  C   . THR A 1 520 ? 137.622 127.613 100.565 1.00 51.12  ? 520 THR A C   1 
ATOM   3440 O  O   . THR A 1 520 ? 136.566 127.635 101.208 1.00 51.12  ? 520 THR A O   1 
ATOM   3441 C  CB  . THR A 1 520 ? 139.734 128.383 101.668 1.00 51.12  ? 520 THR A CB  1 
ATOM   3442 O  OG1 . THR A 1 520 ? 141.008 127.951 102.160 1.00 51.12  ? 520 THR A OG1 1 
ATOM   3443 C  CG2 . THR A 1 520 ? 139.002 129.139 102.764 1.00 51.12  ? 520 THR A CG2 1 
ATOM   3444 N  N   . LEU A 1 521 ? 137.681 127.984 99.284  1.00 49.10  ? 521 LEU A N   1 
ATOM   3445 C  CA  . LEU A 1 521 ? 136.472 128.397 98.577  1.00 49.10  ? 521 LEU A CA  1 
ATOM   3446 C  C   . LEU A 1 521 ? 135.490 127.242 98.426  1.00 49.10  ? 521 LEU A C   1 
ATOM   3447 O  O   . LEU A 1 521 ? 134.280 127.424 98.604  1.00 49.10  ? 521 LEU A O   1 
ATOM   3448 C  CB  . LEU A 1 521 ? 136.834 128.985 97.213  1.00 49.10  ? 521 LEU A CB  1 
ATOM   3449 C  CG  . LEU A 1 521 ? 137.170 130.480 97.124  1.00 49.10  ? 521 LEU A CG  1 
ATOM   3450 C  CD1 . LEU A 1 521 ? 135.958 131.318 97.460  1.00 49.10  ? 521 LEU A CD1 1 
ATOM   3451 C  CD2 . LEU A 1 521 ? 138.327 130.875 98.021  1.00 49.10  ? 521 LEU A CD2 1 
ATOM   3452 N  N   . CYS A 1 522 ? 135.985 126.045 98.107  1.00 46.14  ? 522 CYS A N   1 
ATOM   3453 C  CA  . CYS A 1 522 ? 135.122 124.888 97.918  1.00 46.14  ? 522 CYS A CA  1 
ATOM   3454 C  C   . CYS A 1 522 ? 134.664 124.261 99.227  1.00 46.14  ? 522 CYS A C   1 
ATOM   3455 O  O   . CYS A 1 522 ? 133.729 123.454 99.211  1.00 46.14  ? 522 CYS A O   1 
ATOM   3456 C  CB  . CYS A 1 522 ? 135.837 123.836 97.068  1.00 46.14  ? 522 CYS A CB  1 
ATOM   3457 S  SG  . CYS A 1 522 ? 136.109 124.330 95.353  1.00 46.14  ? 522 CYS A SG  1 
ATOM   3458 N  N   . THR A 1 523 ? 135.299 124.600 100.351 1.00 43.94  ? 523 THR A N   1 
ATOM   3459 C  CA  . THR A 1 523 ? 134.848 124.083 101.638 1.00 43.94  ? 523 THR A CA  1 
ATOM   3460 C  C   . THR A 1 523 ? 133.453 124.593 101.972 1.00 43.94  ? 523 THR A C   1 
ATOM   3461 O  O   . THR A 1 523 ? 132.625 123.854 102.518 1.00 43.94  ? 523 THR A O   1 
ATOM   3462 C  CB  . THR A 1 523 ? 135.835 124.474 102.738 1.00 43.94  ? 523 THR A CB  1 
ATOM   3463 O  OG1 . THR A 1 523 ? 137.148 124.022 102.389 1.00 43.94  ? 523 THR A OG1 1 
ATOM   3464 C  CG2 . THR A 1 523 ? 135.434 123.848 104.062 1.00 43.94  ? 523 THR A CG2 1 
ATOM   3465 N  N   . SER A 1 524 ? 133.173 125.855 101.645 1.00 43.84  ? 524 SER A N   1 
ATOM   3466 C  CA  . SER A 1 524 ? 131.872 126.450 101.921 1.00 43.84  ? 524 SER A CA  1 
ATOM   3467 C  C   . SER A 1 524 ? 130.756 125.860 101.071 1.00 43.84  ? 524 SER A C   1 
ATOM   3468 O  O   . SER A 1 524 ? 129.582 126.100 101.372 1.00 43.84  ? 524 SER A O   1 
ATOM   3469 C  CB  . SER A 1 524 ? 131.937 127.961 101.704 1.00 43.84  ? 524 SER A CB  1 
ATOM   3470 O  OG  . SER A 1 524 ? 132.829 128.572 102.619 1.00 43.84  ? 524 SER A OG  1 
ATOM   3471 N  N   . PHE A 1 525 ? 131.084 125.102 100.025 1.00 41.45  ? 525 PHE A N   1 
ATOM   3472 C  CA  . PHE A 1 525 ? 130.076 124.503 99.151  1.00 41.45  ? 525 PHE A CA  1 
ATOM   3473 C  C   . PHE A 1 525 ? 129.530 123.235 99.807  1.00 41.45  ? 525 PHE A C   1 
ATOM   3474 O  O   . PHE A 1 525 ? 129.797 122.105 99.394  1.00 41.45  ? 525 PHE A O   1 
ATOM   3475 C  CB  . PHE A 1 525 ? 130.662 124.212 97.777  1.00 41.45  ? 525 PHE A CB  1 
ATOM   3476 C  CG  . PHE A 1 525 ? 131.053 125.441 97.014  1.00 41.45  ? 525 PHE A CG  1 
ATOM   3477 C  CD1 . PHE A 1 525 ? 130.431 126.650 97.258  1.00 41.45  ? 525 PHE A CD1 1 
ATOM   3478 C  CD2 . PHE A 1 525 ? 132.043 125.385 96.051  1.00 41.45  ? 525 PHE A CD2 1 
ATOM   3479 C  CE1 . PHE A 1 525 ? 130.790 127.780 96.557  1.00 41.45  ? 525 PHE A CE1 1 
ATOM   3480 C  CE2 . PHE A 1 525 ? 132.406 126.513 95.347  1.00 41.45  ? 525 PHE A CE2 1 
ATOM   3481 C  CZ  . PHE A 1 525 ? 131.779 127.712 95.601  1.00 41.45  ? 525 PHE A CZ  1 
ATOM   3482 N  N   . ALA A 1 526 ? 128.744 123.447 100.858 1.00 40.65  ? 526 ALA A N   1 
ATOM   3483 C  CA  . ALA A 1 526 ? 128.110 122.372 101.614 1.00 40.65  ? 526 ALA A CA  1 
ATOM   3484 C  C   . ALA A 1 526 ? 126.601 122.568 101.511 1.00 40.65  ? 526 ALA A C   1 
ATOM   3485 O  O   . ALA A 1 526 ? 126.007 123.317 102.290 1.00 40.65  ? 526 ALA A O   1 
ATOM   3486 C  CB  . ALA A 1 526 ? 128.586 122.372 103.060 1.00 40.65  ? 526 ALA A CB  1 
ATOM   3487 N  N   . PHE A 1 527 ? 125.979 121.889 100.545 1.00 40.40  ? 527 PHE A N   1 
ATOM   3488 C  CA  . PHE A 1 527 ? 124.569 122.095 100.246 1.00 40.40  ? 527 PHE A CA  1 
ATOM   3489 C  C   . PHE A 1 527 ? 123.727 120.828 100.239 1.00 40.40  ? 527 PHE A C   1 
ATOM   3490 O  O   . PHE A 1 527 ? 122.497 120.937 100.233 1.00 40.40  ? 527 PHE A O   1 
ATOM   3491 C  CB  . PHE A 1 527 ? 124.407 122.782 98.881  1.00 40.40  ? 527 PHE A CB  1 
ATOM   3492 C  CG  . PHE A 1 527 ? 125.190 124.055 98.741  1.00 40.40  ? 527 PHE A CG  1 
ATOM   3493 C  CD1 . PHE A 1 527 ? 125.152 125.021 99.728  1.00 40.40  ? 527 PHE A CD1 1 
ATOM   3494 C  CD2 . PHE A 1 527 ? 125.955 124.289 97.613  1.00 40.40  ? 527 PHE A CD2 1 
ATOM   3495 C  CE1 . PHE A 1 527 ? 125.867 126.191 99.597  1.00 40.40  ? 527 PHE A CE1 1 
ATOM   3496 C  CE2 . PHE A 1 527 ? 126.672 125.459 97.477  1.00 40.40  ? 527 PHE A CE2 1 
ATOM   3497 C  CZ  . PHE A 1 527 ? 126.627 126.411 98.469  1.00 40.40  ? 527 PHE A CZ  1 
ATOM   3498 N  N   . LEU A 1 528 ? 124.335 119.640 100.238 1.00 40.23  ? 528 LEU A N   1 
ATOM   3499 C  CA  . LEU A 1 528 ? 123.570 118.418 100.005 1.00 40.23  ? 528 LEU A CA  1 
ATOM   3500 C  C   . LEU A 1 528 ? 122.638 118.093 101.167 1.00 40.23  ? 528 LEU A C   1 
ATOM   3501 O  O   . LEU A 1 528 ? 121.500 117.661 100.950 1.00 40.23  ? 528 LEU A O   1 
ATOM   3502 C  CB  . LEU A 1 528 ? 124.518 117.250 99.740  1.00 40.23  ? 528 LEU A CB  1 
ATOM   3503 C  CG  . LEU A 1 528 ? 124.999 117.094 98.297  1.00 40.23  ? 528 LEU A CG  1 
ATOM   3504 C  CD1 . LEU A 1 528 ? 125.737 115.779 98.116  1.00 40.23  ? 528 LEU A CD1 1 
ATOM   3505 C  CD2 . LEU A 1 528 ? 123.832 117.191 97.333  1.00 40.23  ? 528 LEU A CD2 1 
ATOM   3506 N  N   . LEU A 1 529 ? 123.090 118.287 102.398 1.00 36.62  ? 529 LEU A N   1 
ATOM   3507 C  CA  . LEU A 1 529 ? 122.375 117.819 103.574 1.00 36.62  ? 529 LEU A CA  1 
ATOM   3508 C  C   . LEU A 1 529 ? 122.209 118.942 104.584 1.00 36.62  ? 529 LEU A C   1 
ATOM   3509 O  O   . LEU A 1 529 ? 122.982 119.906 104.587 1.00 36.62  ? 529 LEU A O   1 
ATOM   3510 C  CB  . LEU A 1 529 ? 123.114 116.641 104.226 1.00 36.62  ? 529 LEU A CB  1 
ATOM   3511 C  CG  . LEU A 1 529 ? 123.403 115.439 103.326 1.00 36.62  ? 529 LEU A CG  1 
ATOM   3512 C  CD1 . LEU A 1 529 ? 124.482 114.564 103.934 1.00 36.62  ? 529 LEU A CD1 1 
ATOM   3513 C  CD2 . LEU A 1 529 ? 122.138 114.636 103.080 1.00 36.62  ? 529 LEU A CD2 1 
ATOM   3514 N  N   . PRO A 1 530 ? 121.190 118.858 105.443 1.00 36.00  ? 530 PRO A N   1 
ATOM   3515 C  CA  . PRO A 1 530 ? 121.061 119.849 106.524 1.00 36.00  ? 530 PRO A CA  1 
ATOM   3516 C  C   . PRO A 1 530 ? 122.240 119.861 107.479 1.00 36.00  ? 530 PRO A C   1 
ATOM   3517 O  O   . PRO A 1 530 ? 122.565 120.916 108.038 1.00 36.00  ? 530 PRO A O   1 
ATOM   3518 C  CB  . PRO A 1 530 ? 119.766 119.427 107.230 1.00 36.00  ? 530 PRO A CB  1 
ATOM   3519 C  CG  . PRO A 1 530 ? 119.004 118.666 106.198 1.00 36.00  ? 530 PRO A CG  1 
ATOM   3520 C  CD  . PRO A 1 530 ? 120.040 117.940 105.398 1.00 36.00  ? 530 PRO A CD  1 
ATOM   3521 N  N   . VAL A 1 531 ? 122.888 118.713 107.692 1.00 32.64  ? 531 VAL A N   1 
ATOM   3522 C  CA  . VAL A 1 531 ? 124.037 118.652 108.586 1.00 32.64  ? 531 VAL A CA  1 
ATOM   3523 C  C   . VAL A 1 531 ? 125.262 119.323 107.978 1.00 32.64  ? 531 VAL A C   1 
ATOM   3524 O  O   . VAL A 1 531 ? 126.222 119.624 108.697 1.00 32.64  ? 531 VAL A O   1 
ATOM   3525 C  CB  . VAL A 1 531 ? 124.331 117.183 108.950 1.00 32.64  ? 531 VAL A CB  1 
ATOM   3526 C  CG1 . VAL A 1 531 ? 124.864 116.429 107.741 1.00 32.64  ? 531 VAL A CG1 1 
ATOM   3527 C  CG2 . VAL A 1 531 ? 125.293 117.088 110.129 1.00 32.64  ? 531 VAL A CG2 1 
ATOM   3528 N  N   . ALA A 1 532 ? 125.247 119.584 106.668 1.00 36.60  ? 532 ALA A N   1 
ATOM   3529 C  CA  . ALA A 1 532 ? 126.435 120.094 105.992 1.00 36.60  ? 532 ALA A CA  1 
ATOM   3530 C  C   . ALA A 1 532 ? 126.869 121.439 106.562 1.00 36.60  ? 532 ALA A C   1 
ATOM   3531 O  O   . ALA A 1 532 ? 128.047 121.641 106.876 1.00 36.60  ? 532 ALA A O   1 
ATOM   3532 C  CB  . ALA A 1 532 ? 126.171 120.200 104.491 1.00 36.60  ? 532 ALA A CB  1 
ATOM   3533 N  N   . ASN A 1 533 ? 125.933 122.373 106.708 1.00 38.87  ? 533 ASN A N   1 
ATOM   3534 C  CA  . ASN A 1 533 ? 126.227 123.651 107.339 1.00 38.87  ? 533 ASN A CA  1 
ATOM   3535 C  C   . ASN A 1 533 ? 125.002 124.111 108.114 1.00 38.87  ? 533 ASN A C   1 
ATOM   3536 O  O   . ASN A 1 533 ? 123.875 123.744 107.762 1.00 38.87  ? 533 ASN A O   1 
ATOM   3537 C  CB  . ASN A 1 533 ? 126.649 124.714 106.312 1.00 38.87  ? 533 ASN A CB  1 
ATOM   3538 C  CG  . ASN A 1 533 ? 125.754 124.738 105.098 1.00 38.87  ? 533 ASN A CG  1 
ATOM   3539 O  OD1 . ASN A 1 533 ? 124.807 123.962 104.999 1.00 38.87  ? 533 ASN A OD1 1 
ATOM   3540 N  ND2 . ASN A 1 533 ? 126.050 125.631 104.162 1.00 38.87  ? 533 ASN A ND2 1 
ATOM   3541 N  N   . PRO A 1 534 ? 125.189 124.897 109.170 1.00 36.30  ? 534 PRO A N   1 
ATOM   3542 C  CA  . PRO A 1 534 ? 124.062 125.302 110.025 1.00 36.30  ? 534 PRO A CA  1 
ATOM   3543 C  C   . PRO A 1 534 ? 122.971 126.054 109.276 1.00 36.30  ? 534 PRO A C   1 
ATOM   3544 O  O   . PRO A 1 534 ? 121.794 125.925 109.644 1.00 36.30  ? 534 PRO A O   1 
ATOM   3545 C  CB  . PRO A 1 534 ? 124.730 126.191 111.084 1.00 36.30  ? 534 PRO A CB  1 
ATOM   3546 C  CG  . PRO A 1 534 ? 126.112 125.655 111.179 1.00 36.30  ? 534 PRO A CG  1 
ATOM   3547 C  CD  . PRO A 1 534 ? 126.488 125.223 109.787 1.00 36.30  ? 534 PRO A CD  1 
ATOM   3548 N  N   . PRO A 1 535 ? 123.290 126.880 108.263 1.00 38.05  ? 535 PRO A N   1 
ATOM   3549 C  CA  . PRO A 1 535 ? 122.189 127.497 107.499 1.00 38.05  ? 535 PRO A CA  1 
ATOM   3550 C  C   . PRO A 1 535 ? 121.227 126.489 106.894 1.00 38.05  ? 535 PRO A C   1 
ATOM   3551 O  O   . PRO A 1 535 ? 120.010 126.720 106.890 1.00 38.05  ? 535 PRO A O   1 
ATOM   3552 C  CB  . PRO A 1 535 ? 122.925 128.298 106.419 1.00 38.05  ? 535 PRO A CB  1 
ATOM   3553 C  CG  . PRO A 1 535 ? 124.183 128.685 107.061 1.00 38.05  ? 535 PRO A CG  1 
ATOM   3554 C  CD  . PRO A 1 535 ? 124.576 127.531 107.940 1.00 38.05  ? 535 PRO A CD  1 
ATOM   3555 N  N   . ASN A 1 536 ? 121.740 125.364 106.394 1.00 40.51  ? 536 ASN A N   1 
ATOM   3556 C  CA  . ASN A 1 536 ? 120.864 124.334 105.848 1.00 40.51  ? 536 ASN A CA  1 
ATOM   3557 C  C   . ASN A 1 536 ? 119.959 123.757 106.927 1.00 40.51  ? 536 ASN A C   1 
ATOM   3558 O  O   . ASN A 1 536 ? 118.774 123.511 106.685 1.00 40.51  ? 536 ASN A O   1 
ATOM   3559 C  CB  . ASN A 1 536 ? 121.692 123.229 105.197 1.00 40.51  ? 536 ASN A CB  1 
ATOM   3560 C  CG  . ASN A 1 536 ? 122.142 123.588 103.799 1.00 40.51  ? 536 ASN A CG  1 
ATOM   3561 O  OD1 . ASN A 1 536 ? 122.075 124.746 103.392 1.00 40.51  ? 536 ASN A OD1 1 
ATOM   3562 N  ND2 . ASN A 1 536 ? 122.610 122.595 103.056 1.00 40.51  ? 536 ASN A ND2 1 
ATOM   3563 N  N   . ALA A 1 537 ? 120.502 123.531 108.126 1.00 40.26  ? 537 ALA A N   1 
ATOM   3564 C  CA  . ALA A 1 537 ? 119.687 123.018 109.222 1.00 40.26  ? 537 ALA A CA  1 
ATOM   3565 C  C   . ALA A 1 537 ? 118.616 124.020 109.634 1.00 40.26  ? 537 ALA A C   1 
ATOM   3566 O  O   . ALA A 1 537 ? 117.469 123.638 109.893 1.00 40.26  ? 537 ALA A O   1 
ATOM   3567 C  CB  . ALA A 1 537 ? 120.575 122.658 110.410 1.00 40.26  ? 537 ALA A CB  1 
ATOM   3568 N  N   . ILE A 1 538 ? 118.969 125.306 109.694 1.00 40.99  ? 538 ILE A N   1 
ATOM   3569 C  CA  . ILE A 1 538 ? 117.990 126.334 110.036 1.00 40.99  ? 538 ILE A CA  1 
ATOM   3570 C  C   . ILE A 1 538 ? 116.865 126.357 109.013 1.00 40.99  ? 538 ILE A C   1 
ATOM   3571 O  O   . ILE A 1 538 ? 115.682 126.425 109.368 1.00 40.99  ? 538 ILE A O   1 
ATOM   3572 C  CB  . ILE A 1 538 ? 118.672 127.710 110.145 1.00 40.99  ? 538 ILE A CB  1 
ATOM   3573 C  CG1 . ILE A 1 538 ? 119.683 127.723 111.288 1.00 40.99  ? 538 ILE A CG1 1 
ATOM   3574 C  CG2 . ILE A 1 538 ? 117.637 128.808 110.329 1.00 40.99  ? 538 ILE A CG2 1 
ATOM   3575 C  CD1 . ILE A 1 538 ? 120.672 128.847 111.186 1.00 40.99  ? 538 ILE A CD1 1 
ATOM   3576 N  N   . VAL A 1 539 ? 117.216 126.304 107.729 1.00 45.19  ? 539 VAL A N   1 
ATOM   3577 C  CA  . VAL A 1 539 ? 116.205 126.310 106.676 1.00 45.19  ? 539 VAL A CA  1 
ATOM   3578 C  C   . VAL A 1 539 ? 115.328 125.066 106.758 1.00 45.19  ? 539 VAL A C   1 
ATOM   3579 O  O   . VAL A 1 539 ? 114.099 125.145 106.636 1.00 45.19  ? 539 VAL A O   1 
ATOM   3580 C  CB  . VAL A 1 539 ? 116.885 126.449 105.304 1.00 45.19  ? 539 VAL A CB  1 
ATOM   3581 C  CG1 . VAL A 1 539 ? 115.955 126.013 104.203 1.00 45.19  ? 539 VAL A CG1 1 
ATOM   3582 C  CG2 . VAL A 1 539 ? 117.314 127.886 105.092 1.00 45.19  ? 539 VAL A CG2 1 
ATOM   3583 N  N   . PHE A 1 540 ? 115.939 123.901 106.976 1.00 50.20  ? 540 PHE A N   1 
ATOM   3584 C  CA  . PHE A 1 540 ? 115.190 122.653 107.026 1.00 50.20  ? 540 PHE A CA  1 
ATOM   3585 C  C   . PHE A 1 540 ? 114.326 122.547 108.277 1.00 50.20  ? 540 PHE A C   1 
ATOM   3586 O  O   . PHE A 1 540 ? 113.371 121.763 108.291 1.00 50.20  ? 540 PHE A O   1 
ATOM   3587 C  CB  . PHE A 1 540 ? 116.167 121.477 106.946 1.00 50.20  ? 540 PHE A CB  1 
ATOM   3588 C  CG  . PHE A 1 540 ? 115.508 120.129 106.943 1.00 50.20  ? 540 PHE A CG  1 
ATOM   3589 C  CD1 . PHE A 1 540 ? 114.879 119.655 105.805 1.00 50.20  ? 540 PHE A CD1 1 
ATOM   3590 C  CD2 . PHE A 1 540 ? 115.532 119.330 108.072 1.00 50.20  ? 540 PHE A CD2 1 
ATOM   3591 C  CE1 . PHE A 1 540 ? 114.278 118.412 105.796 1.00 50.20  ? 540 PHE A CE1 1 
ATOM   3592 C  CE2 . PHE A 1 540 ? 114.931 118.085 108.070 1.00 50.20  ? 540 PHE A CE2 1 
ATOM   3593 C  CZ  . PHE A 1 540 ? 114.304 117.626 106.930 1.00 50.20  ? 540 PHE A CZ  1 
ATOM   3594 N  N   . SER A 1 541 ? 114.639 123.318 109.323 1.00 50.16  ? 541 SER A N   1 
ATOM   3595 C  CA  . SER A 1 541 ? 113.869 123.252 110.561 1.00 50.16  ? 541 SER A CA  1 
ATOM   3596 C  C   . SER A 1 541 ? 112.425 123.703 110.388 1.00 50.16  ? 541 SER A C   1 
ATOM   3597 O  O   . SER A 1 541 ? 111.576 123.338 111.208 1.00 50.16  ? 541 SER A O   1 
ATOM   3598 C  CB  . SER A 1 541 ? 114.544 124.098 111.640 1.00 50.16  ? 541 SER A CB  1 
ATOM   3599 O  OG  . SER A 1 541 ? 114.099 125.441 111.583 1.00 50.16  ? 541 SER A OG  1 
ATOM   3600 N  N   . TYR A 1 542 ? 112.122 124.488 109.352 1.00 54.16  ? 542 TYR A N   1 
ATOM   3601 C  CA  . TYR A 1 542 ? 110.751 124.949 109.156 1.00 54.16  ? 542 TYR A CA  1 
ATOM   3602 C  C   . TYR A 1 542 ? 109.837 123.857 108.616 1.00 54.16  ? 542 TYR A C   1 
ATOM   3603 O  O   . TYR A 1 542 ? 108.613 124.012 108.669 1.00 54.16  ? 542 TYR A O   1 
ATOM   3604 C  CB  . TYR A 1 542 ? 110.721 126.169 108.230 1.00 54.16  ? 542 TYR A CB  1 
ATOM   3605 C  CG  . TYR A 1 542 ? 111.330 127.416 108.838 1.00 54.16  ? 542 TYR A CG  1 
ATOM   3606 C  CD1 . TYR A 1 542 ? 112.686 127.489 109.122 1.00 54.16  ? 542 TYR A CD1 1 
ATOM   3607 C  CD2 . TYR A 1 542 ? 110.540 128.517 109.139 1.00 54.16  ? 542 TYR A CD2 1 
ATOM   3608 C  CE1 . TYR A 1 542 ? 113.239 128.624 109.684 1.00 54.16  ? 542 TYR A CE1 1 
ATOM   3609 C  CE2 . TYR A 1 542 ? 111.083 129.656 109.699 1.00 54.16  ? 542 TYR A CE2 1 
ATOM   3610 C  CZ  . TYR A 1 542 ? 112.433 129.704 109.970 1.00 54.16  ? 542 TYR A CZ  1 
ATOM   3611 O  OH  . TYR A 1 542 ? 112.983 130.837 110.527 1.00 54.16  ? 542 TYR A OH  1 
ATOM   3612 N  N   . GLY A 1 543 ? 110.395 122.766 108.099 1.00 56.73  ? 543 GLY A N   1 
ATOM   3613 C  CA  . GLY A 1 543 ? 109.601 121.628 107.689 1.00 56.73  ? 543 GLY A CA  1 
ATOM   3614 C  C   . GLY A 1 543 ? 108.978 121.728 106.316 1.00 56.73  ? 543 GLY A C   1 
ATOM   3615 O  O   . GLY A 1 543 ? 108.316 120.774 105.886 1.00 56.73  ? 543 GLY A O   1 
ATOM   3616 N  N   . HIS A 1 544 ? 109.157 122.847 105.613 1.00 59.17  ? 544 HIS A N   1 
ATOM   3617 C  CA  . HIS A 1 544 ? 108.621 122.956 104.261 1.00 59.17  ? 544 HIS A CA  1 
ATOM   3618 C  C   . HIS A 1 544 ? 109.416 122.113 103.274 1.00 59.17  ? 544 HIS A C   1 
ATOM   3619 O  O   . HIS A 1 544 ? 108.843 121.570 102.323 1.00 59.17  ? 544 HIS A O   1 
ATOM   3620 C  CB  . HIS A 1 544 ? 108.605 124.418 103.820 1.00 59.17  ? 544 HIS A CB  1 
ATOM   3621 C  CG  . HIS A 1 544 ? 107.729 125.290 104.661 1.00 59.17  ? 544 HIS A CG  1 
ATOM   3622 N  ND1 . HIS A 1 544 ? 108.186 125.937 105.789 1.00 59.17  ? 544 HIS A ND1 1 
ATOM   3623 C  CD2 . HIS A 1 544 ? 106.421 125.621 104.542 1.00 59.17  ? 544 HIS A CD2 1 
ATOM   3624 C  CE1 . HIS A 1 544 ? 107.198 126.628 106.328 1.00 59.17  ? 544 HIS A CE1 1 
ATOM   3625 N  NE2 . HIS A 1 544 ? 106.117 126.455 105.590 1.00 59.17  ? 544 HIS A NE2 1 
ATOM   3626 N  N   . LEU A 1 545 ? 110.721 121.991 103.482 1.00 53.80  ? 545 LEU A N   1 
ATOM   3627 C  CA  . LEU A 1 545 ? 111.590 121.253 102.582 1.00 53.80  ? 545 LEU A CA  1 
ATOM   3628 C  C   . LEU A 1 545 ? 111.687 119.788 102.993 1.00 53.80  ? 545 LEU A C   1 
ATOM   3629 O  O   . LEU A 1 545 ? 111.353 119.404 104.116 1.00 53.80  ? 545 LEU A O   1 
ATOM   3630 C  CB  . LEU A 1 545 ? 112.985 121.876 102.559 1.00 53.80  ? 545 LEU A CB  1 
ATOM   3631 C  CG  . LEU A 1 545 ? 113.252 122.919 101.478 1.00 53.80  ? 545 LEU A CG  1 
ATOM   3632 C  CD1 . LEU A 1 545 ? 114.534 123.666 101.787 1.00 53.80  ? 545 LEU A CD1 1 
ATOM   3633 C  CD2 . LEU A 1 545 ? 113.329 122.259 100.113 1.00 53.80  ? 545 LEU A CD2 1 
ATOM   3634 N  N   . LYS A 1 546 ? 112.155 118.968 102.056 1.00 57.05  ? 546 LYS A N   1 
ATOM   3635 C  CA  . LYS A 1 546 ? 112.459 117.570 102.312 1.00 57.05  ? 546 LYS A CA  1 
ATOM   3636 C  C   . LYS A 1 546 ? 113.831 117.253 101.730 1.00 57.05  ? 546 LYS A C   1 
ATOM   3637 O  O   . LYS A 1 546 ? 114.363 117.998 100.904 1.00 57.05  ? 546 LYS A O   1 
ATOM   3638 C  CB  . LYS A 1 546 ? 111.380 116.638 101.741 1.00 57.05  ? 546 LYS A CB  1 
ATOM   3639 C  CG  . LYS A 1 546 ? 111.447 116.411 100.244 1.00 57.05  ? 546 LYS A CG  1 
ATOM   3640 C  CD  . LYS A 1 546 ? 110.577 115.227 99.844  1.00 57.05  ? 546 LYS A CD  1 
ATOM   3641 C  CE  . LYS A 1 546 ? 109.098 115.569 99.911  1.00 57.05  ? 546 LYS A CE  1 
ATOM   3642 N  NZ  . LYS A 1 546 ? 108.638 116.288 98.692  1.00 57.05  ? 546 LYS A NZ  1 
ATOM   3643 N  N   . VAL A 1 547 ? 114.403 116.135 102.182 1.00 54.26  ? 547 VAL A N   1 
ATOM   3644 C  CA  . VAL A 1 547 ? 115.825 115.883 101.958 1.00 54.26  ? 547 VAL A CA  1 
ATOM   3645 C  C   . VAL A 1 547 ? 116.145 115.674 100.481 1.00 54.26  ? 547 VAL A C   1 
ATOM   3646 O  O   . VAL A 1 547 ? 117.208 116.099 100.009 1.00 54.26  ? 547 VAL A O   1 
ATOM   3647 C  CB  . VAL A 1 547 ? 116.293 114.696 102.823 1.00 54.26  ? 547 VAL A CB  1 
ATOM   3648 C  CG1 . VAL A 1 547 ? 115.665 113.389 102.356 1.00 54.26  ? 547 VAL A CG1 1 
ATOM   3649 C  CG2 . VAL A 1 547 ? 117.812 114.601 102.820 1.00 54.26  ? 547 VAL A CG2 1 
ATOM   3650 N  N   . ILE A 1 548 ? 115.252 115.036 99.721  1.00 54.11  ? 548 ILE A N   1 
ATOM   3651 C  CA  . ILE A 1 548 ? 115.574 114.726 98.331  1.00 54.11  ? 548 ILE A CA  1 
ATOM   3652 C  C   . ILE A 1 548 ? 115.665 116.002 97.501  1.00 54.11  ? 548 ILE A C   1 
ATOM   3653 O  O   . ILE A 1 548 ? 116.528 116.125 96.624  1.00 54.11  ? 548 ILE A O   1 
ATOM   3654 C  CB  . ILE A 1 548 ? 114.561 113.723 97.746  1.00 54.11  ? 548 ILE A CB  1 
ATOM   3655 C  CG1 . ILE A 1 548 ? 115.049 113.205 96.392  1.00 54.11  ? 548 ILE A CG1 1 
ATOM   3656 C  CG2 . ILE A 1 548 ? 113.179 114.335 97.617  1.00 54.11  ? 548 ILE A CG2 1 
ATOM   3657 C  CD1 . ILE A 1 548 ? 116.369 112.476 96.461  1.00 54.11  ? 548 ILE A CD1 1 
ATOM   3658 N  N   . ASP A 1 549 ? 114.793 116.976 97.769  1.00 55.93  ? 549 ASP A N   1 
ATOM   3659 C  CA  . ASP A 1 549 ? 114.849 118.238 97.038  1.00 55.93  ? 549 ASP A CA  1 
ATOM   3660 C  C   . ASP A 1 549 ? 116.116 119.013 97.377  1.00 55.93  ? 549 ASP A C   1 
ATOM   3661 O  O   . ASP A 1 549 ? 116.740 119.616 96.492  1.00 55.93  ? 549 ASP A O   1 
ATOM   3662 C  CB  . ASP A 1 549 ? 113.605 119.070 97.340  1.00 55.93  ? 549 ASP A CB  1 
ATOM   3663 C  CG  . ASP A 1 549 ? 112.337 118.430 96.808  1.00 55.93  ? 549 ASP A CG  1 
ATOM   3664 O  OD1 . ASP A 1 549 ? 112.410 117.729 95.777  1.00 55.93  ? 549 ASP A OD1 1 
ATOM   3665 O  OD2 . ASP A 1 549 ? 111.267 118.622 97.420  1.00 55.93  ? 549 ASP A OD2 1 
ATOM   3666 N  N   . MET A 1 550 ? 116.513 119.003 98.652  1.00 50.93  ? 550 MET A N   1 
ATOM   3667 C  CA  . MET A 1 550 ? 117.764 119.643 99.042  1.00 50.93  ? 550 MET A CA  1 
ATOM   3668 C  C   . MET A 1 550 ? 118.948 118.994 98.341  1.00 50.93  ? 550 MET A C   1 
ATOM   3669 O  O   . MET A 1 550 ? 119.850 119.686 97.864  1.00 50.93  ? 550 MET A O   1 
ATOM   3670 C  CB  . MET A 1 550 ? 117.946 119.590 100.558 1.00 50.93  ? 550 MET A CB  1 
ATOM   3671 C  CG  . MET A 1 550 ? 116.941 120.414 101.333 1.00 50.93  ? 550 MET A CG  1 
ATOM   3672 S  SD  . MET A 1 550 ? 117.157 120.248 103.112 1.00 50.93  ? 550 MET A SD  1 
ATOM   3673 C  CE  . MET A 1 550 ? 118.695 121.138 103.340 1.00 50.93  ? 550 MET A CE  1 
ATOM   3674 N  N   . VAL A 1 551 ? 118.959 117.662 98.266  1.00 48.31  ? 551 VAL A N   1 
ATOM   3675 C  CA  . VAL A 1 551 ? 120.045 116.967 97.576  1.00 48.31  ? 551 VAL A CA  1 
ATOM   3676 C  C   . VAL A 1 551 ? 120.065 117.344 96.100  1.00 48.31  ? 551 VAL A C   1 
ATOM   3677 O  O   . VAL A 1 551 ? 121.123 117.645 95.530  1.00 48.31  ? 551 VAL A O   1 
ATOM   3678 C  CB  . VAL A 1 551 ? 119.916 115.445 97.765  1.00 48.31  ? 551 VAL A CB  1 
ATOM   3679 C  CG1 . VAL A 1 551 ? 120.934 114.719 96.906  1.00 48.31  ? 551 VAL A CG1 1 
ATOM   3680 C  CG2 . VAL A 1 551 ? 120.102 115.074 99.224  1.00 48.31  ? 551 VAL A CG2 1 
ATOM   3681 N  N   . LYS A 1 552 ? 118.892 117.345 95.462  1.00 49.16  ? 552 LYS A N   1 
ATOM   3682 C  CA  . LYS A 1 552 ? 118.822 117.631 94.033  1.00 49.16  ? 552 LYS A CA  1 
ATOM   3683 C  C   . LYS A 1 552 ? 119.309 119.040 93.722  1.00 49.16  ? 552 LYS A C   1 
ATOM   3684 O  O   . LYS A 1 552 ? 120.041 119.249 92.748  1.00 49.16  ? 552 LYS A O   1 
ATOM   3685 C  CB  . LYS A 1 552 ? 117.393 117.436 93.527  1.00 49.16  ? 552 LYS A CB  1 
ATOM   3686 C  CG  . LYS A 1 552 ? 116.963 115.983 93.422  1.00 49.16  ? 552 LYS A CG  1 
ATOM   3687 C  CD  . LYS A 1 552 ? 115.617 115.857 92.730  1.00 49.16  ? 552 LYS A CD  1 
ATOM   3688 C  CE  . LYS A 1 552 ? 114.521 116.554 93.520  1.00 49.16  ? 552 LYS A CE  1 
ATOM   3689 N  NZ  . LYS A 1 552 ? 113.177 116.329 92.921  1.00 49.16  ? 552 LYS A NZ  1 
ATOM   3690 N  N   . ALA A 1 553 ? 118.912 120.023 94.534  1.00 48.69  ? 553 ALA A N   1 
ATOM   3691 C  CA  . ALA A 1 553 ? 119.367 121.390 94.296  1.00 48.69  ? 553 ALA A CA  1 
ATOM   3692 C  C   . ALA A 1 553 ? 120.843 121.556 94.642  1.00 48.69  ? 553 ALA A C   1 
ATOM   3693 O  O   . ALA A 1 553 ? 121.593 122.215 93.904  1.00 48.69  ? 553 ALA A O   1 
ATOM   3694 C  CB  . ALA A 1 553 ? 118.515 122.371 95.098  1.00 48.69  ? 553 ALA A CB  1 
ATOM   3695 N  N   . GLY A 1 554 ? 121.276 120.964 95.757  1.00 44.29  ? 554 GLY A N   1 
ATOM   3696 C  CA  . GLY A 1 554 ? 122.642 121.148 96.208  1.00 44.29  ? 554 GLY A CA  1 
ATOM   3697 C  C   . GLY A 1 554 ? 123.662 120.529 95.278  1.00 44.29  ? 554 GLY A C   1 
ATOM   3698 O  O   . GLY A 1 554 ? 124.758 121.061 95.118  1.00 44.29  ? 554 GLY A O   1 
ATOM   3699 N  N   . LEU A 1 555 ? 123.325 119.396 94.658  1.00 43.85  ? 555 LEU A N   1 
ATOM   3700 C  CA  . LEU A 1 555 ? 124.257 118.785 93.716  1.00 43.85  ? 555 LEU A CA  1 
ATOM   3701 C  C   . LEU A 1 555 ? 124.552 119.728 92.555  1.00 43.85  ? 555 LEU A C   1 
ATOM   3702 O  O   . LEU A 1 555 ? 125.716 119.952 92.196  1.00 43.85  ? 555 LEU A O   1 
ATOM   3703 C  CB  . LEU A 1 555 ? 123.695 117.458 93.209  1.00 43.85  ? 555 LEU A CB  1 
ATOM   3704 C  CG  . LEU A 1 555 ? 124.634 116.627 92.336  1.00 43.85  ? 555 LEU A CG  1 
ATOM   3705 C  CD1 . LEU A 1 555 ? 125.894 116.270 93.104  1.00 43.85  ? 555 LEU A CD1 1 
ATOM   3706 C  CD2 . LEU A 1 555 ? 123.933 115.374 91.837  1.00 43.85  ? 555 LEU A CD2 1 
ATOM   3707 N  N   . GLY A 1 556 ? 123.505 120.315 91.974  1.00 42.54  ? 556 GLY A N   1 
ATOM   3708 C  CA  . GLY A 1 556 ? 123.708 121.247 90.878  1.00 42.54  ? 556 GLY A CA  1 
ATOM   3709 C  C   . GLY A 1 556 ? 124.440 122.505 91.304  1.00 42.54  ? 556 GLY A C   1 
ATOM   3710 O  O   . GLY A 1 556 ? 125.341 122.978 90.604  1.00 42.54  ? 556 GLY A O   1 
ATOM   3711 N  N   . VAL A 1 557 ? 124.067 123.065 92.458  1.00 43.29  ? 557 VAL A N   1 
ATOM   3712 C  CA  . VAL A 1 557 ? 124.732 124.282 92.914  1.00 43.29  ? 557 VAL A CA  1 
ATOM   3713 C  C   . VAL A 1 557 ? 126.201 124.009 93.215  1.00 43.29  ? 557 VAL A C   1 
ATOM   3714 O  O   . VAL A 1 557 ? 127.070 124.838 92.928  1.00 43.29  ? 557 VAL A O   1 
ATOM   3715 C  CB  . VAL A 1 557 ? 123.998 124.879 94.128  1.00 43.29  ? 557 VAL A CB  1 
ATOM   3716 C  CG1 . VAL A 1 557 ? 124.727 126.108 94.634  1.00 43.29  ? 557 VAL A CG1 1 
ATOM   3717 C  CG2 . VAL A 1 557 ? 122.576 125.245 93.752  1.00 43.29  ? 557 VAL A CG2 1 
ATOM   3718 N  N   . ASN A 1 558 ? 126.506 122.838 93.779  1.00 40.70  ? 558 ASN A N   1 
ATOM   3719 C  CA  . ASN A 1 558 ? 127.889 122.481 94.072  1.00 40.70  ? 558 ASN A CA  1 
ATOM   3720 C  C   . ASN A 1 558 ? 128.691 122.278 92.795  1.00 40.70  ? 558 ASN A C   1 
ATOM   3721 O  O   . ASN A 1 558 ? 129.856 122.684 92.720  1.00 40.70  ? 558 ASN A O   1 
ATOM   3722 C  CB  . ASN A 1 558 ? 127.923 121.223 94.940  1.00 40.70  ? 558 ASN A CB  1 
ATOM   3723 C  CG  . ASN A 1 558 ? 129.225 121.070 95.693  1.00 40.70  ? 558 ASN A CG  1 
ATOM   3724 O  OD1 . ASN A 1 558 ? 130.138 121.880 95.550  1.00 40.70  ? 558 ASN A OD1 1 
ATOM   3725 N  ND2 . ASN A 1 558 ? 129.315 120.027 96.509  1.00 40.70  ? 558 ASN A ND2 1 
ATOM   3726 N  N   . ILE A 1 559 ? 128.090 121.651 91.780  1.00 42.01  ? 559 ILE A N   1 
ATOM   3727 C  CA  . ILE A 1 559 ? 128.776 121.498 90.498  1.00 42.01  ? 559 ILE A CA  1 
ATOM   3728 C  C   . ILE A 1 559 ? 129.087 122.864 89.899  1.00 42.01  ? 559 ILE A C   1 
ATOM   3729 O  O   . ILE A 1 559 ? 130.205 123.121 89.430  1.00 42.01  ? 559 ILE A O   1 
ATOM   3730 C  CB  . ILE A 1 559 ? 127.936 120.639 89.536  1.00 42.01  ? 559 ILE A CB  1 
ATOM   3731 C  CG1 . ILE A 1 559 ? 127.978 119.170 89.956  1.00 42.01  ? 559 ILE A CG1 1 
ATOM   3732 C  CG2 . ILE A 1 559 ? 128.423 120.804 88.107  1.00 42.01  ? 559 ILE A CG2 1 
ATOM   3733 C  CD1 . ILE A 1 559 ? 127.040 118.287 89.168  1.00 42.01  ? 559 ILE A CD1 1 
ATOM   3734 N  N   . VAL A 1 560 ? 128.102 123.766 89.920  1.00 41.66  ? 560 VAL A N   1 
ATOM   3735 C  CA  . VAL A 1 560 ? 128.310 125.107 89.381  1.00 41.66  ? 560 VAL A CA  1 
ATOM   3736 C  C   . VAL A 1 560 ? 129.412 125.826 90.147  1.00 41.66  ? 560 VAL A C   1 
ATOM   3737 O  O   . VAL A 1 560 ? 130.290 126.464 89.551  1.00 41.66  ? 560 VAL A O   1 
ATOM   3738 C  CB  . VAL A 1 560 ? 126.994 125.904 89.406  1.00 41.66  ? 560 VAL A CB  1 
ATOM   3739 C  CG1 . VAL A 1 560 ? 127.259 127.367 89.116  1.00 41.66  ? 560 VAL A CG1 1 
ATOM   3740 C  CG2 . VAL A 1 560 ? 126.011 125.333 88.402  1.00 41.66  ? 560 VAL A CG2 1 
ATOM   3741 N  N   . GLY A 1 561 ? 129.385 125.736 91.477  1.00 42.59  ? 561 GLY A N   1 
ATOM   3742 C  CA  . GLY A 1 561 ? 130.397 126.403 92.276  1.00 42.59  ? 561 GLY A CA  1 
ATOM   3743 C  C   . GLY A 1 561 ? 131.793 125.872 92.020  1.00 42.59  ? 561 GLY A C   1 
ATOM   3744 O  O   . GLY A 1 561 ? 132.746 126.644 91.904  1.00 42.59  ? 561 GLY A O   1 
ATOM   3745 N  N   . VAL A 1 562 ? 131.933 124.548 91.927  1.00 44.72  ? 562 VAL A N   1 
ATOM   3746 C  CA  . VAL A 1 562 ? 133.243 123.961 91.660  1.00 44.72  ? 562 VAL A CA  1 
ATOM   3747 C  C   . VAL A 1 562 ? 133.753 124.399 90.294  1.00 44.72  ? 562 VAL A C   1 
ATOM   3748 O  O   . VAL A 1 562 ? 134.926 124.768 90.142  1.00 44.72  ? 562 VAL A O   1 
ATOM   3749 C  CB  . VAL A 1 562 ? 133.179 122.428 91.780  1.00 44.72  ? 562 VAL A CB  1 
ATOM   3750 C  CG1 . VAL A 1 562 ? 134.430 121.797 91.196  1.00 44.72  ? 562 VAL A CG1 1 
ATOM   3751 C  CG2 . VAL A 1 562 ? 133.011 122.021 93.234  1.00 44.72  ? 562 VAL A CG2 1 
ATOM   3752 N  N   . ALA A 1 563 ? 132.880 124.382 89.281  1.00 45.01  ? 563 ALA A N   1 
ATOM   3753 C  CA  . ALA A 1 563 ? 133.301 124.800 87.948  1.00 45.01  ? 563 ALA A CA  1 
ATOM   3754 C  C   . ALA A 1 563 ? 133.730 126.263 87.933  1.00 45.01  ? 563 ALA A C   1 
ATOM   3755 O  O   . ALA A 1 563 ? 134.756 126.612 87.335  1.00 45.01  ? 563 ALA A O   1 
ATOM   3756 C  CB  . ALA A 1 563 ? 132.176 124.561 86.943  1.00 45.01  ? 563 ALA A CB  1 
ATOM   3757 N  N   . VAL A 1 564 ? 132.966 127.132 88.598  1.00 45.54  ? 564 VAL A N   1 
ATOM   3758 C  CA  . VAL A 1 564 ? 133.292 128.555 88.592  1.00 45.54  ? 564 VAL A CA  1 
ATOM   3759 C  C   . VAL A 1 564 ? 134.580 128.818 89.362  1.00 45.54  ? 564 VAL A C   1 
ATOM   3760 O  O   . VAL A 1 564 ? 135.399 129.650 88.955  1.00 45.54  ? 564 VAL A O   1 
ATOM   3761 C  CB  . VAL A 1 564 ? 132.115 129.376 89.146  1.00 45.54  ? 564 VAL A CB  1 
ATOM   3762 C  CG1 . VAL A 1 564 ? 132.540 130.813 89.404  1.00 45.54  ? 564 VAL A CG1 1 
ATOM   3763 C  CG2 . VAL A 1 564 ? 130.946 129.337 88.178  1.00 45.54  ? 564 VAL A CG2 1 
ATOM   3764 N  N   . VAL A 1 565 ? 134.785 128.123 90.483  1.00 48.19  ? 565 VAL A N   1 
ATOM   3765 C  CA  . VAL A 1 565 ? 136.020 128.297 91.244  1.00 48.19  ? 565 VAL A CA  1 
ATOM   3766 C  C   . VAL A 1 565 ? 137.219 127.835 90.426  1.00 48.19  ? 565 VAL A C   1 
ATOM   3767 O  O   . VAL A 1 565 ? 138.271 128.486 90.420  1.00 48.19  ? 565 VAL A O   1 
ATOM   3768 C  CB  . VAL A 1 565 ? 135.932 127.557 92.591  1.00 48.19  ? 565 VAL A CB  1 
ATOM   3769 C  CG1 . VAL A 1 565 ? 137.300 127.477 93.243  1.00 48.19  ? 565 VAL A CG1 1 
ATOM   3770 C  CG2 . VAL A 1 565 ? 134.954 128.263 93.513  1.00 48.19  ? 565 VAL A CG2 1 
ATOM   3771 N  N   . MET A 1 566 ? 137.082 126.709 89.721  1.00 56.16  ? 566 MET A N   1 
ATOM   3772 C  CA  . MET A 1 566 ? 138.170 126.240 88.870  1.00 56.16  ? 566 MET A CA  1 
ATOM   3773 C  C   . MET A 1 566 ? 138.472 127.243 87.762  1.00 56.16  ? 566 MET A C   1 
ATOM   3774 O  O   . MET A 1 566 ? 139.641 127.530 87.473  1.00 56.16  ? 566 MET A O   1 
ATOM   3775 C  CB  . MET A 1 566 ? 137.819 124.874 88.278  1.00 56.16  ? 566 MET A CB  1 
ATOM   3776 C  CG  . MET A 1 566 ? 138.419 123.677 89.016  1.00 56.16  ? 566 MET A CG  1 
ATOM   3777 S  SD  . MET A 1 566 ? 140.170 123.756 89.462  1.00 56.16  ? 566 MET A SD  1 
ATOM   3778 C  CE  . MET A 1 566 ? 140.928 124.395 87.968  1.00 56.16  ? 566 MET A CE  1 
ATOM   3779 N  N   . LEU A 1 567 ? 137.427 127.794 87.139  1.00 55.50  ? 567 LEU A N   1 
ATOM   3780 C  CA  . LEU A 1 567 ? 137.628 128.793 86.094  1.00 55.50  ? 567 LEU A CA  1 
ATOM   3781 C  C   . LEU A 1 567 ? 138.322 130.033 86.642  1.00 55.50  ? 567 LEU A C   1 
ATOM   3782 O  O   . LEU A 1 567 ? 139.236 130.574 86.008  1.00 55.50  ? 567 LEU A O   1 
ATOM   3783 C  CB  . LEU A 1 567 ? 136.283 129.153 85.459  1.00 55.50  ? 567 LEU A CB  1 
ATOM   3784 C  CG  . LEU A 1 567 ? 136.222 130.051 84.220  1.00 55.50  ? 567 LEU A CG  1 
ATOM   3785 C  CD1 . LEU A 1 567 ? 134.969 129.736 83.424  1.00 55.50  ? 567 LEU A CD1 1 
ATOM   3786 C  CD2 . LEU A 1 567 ? 136.230 131.526 84.596  1.00 55.50  ? 567 LEU A CD2 1 
ATOM   3787 N  N   . GLY A 1 568 ? 137.901 130.499 87.818  1.00 59.71  ? 568 GLY A N   1 
ATOM   3788 C  CA  . GLY A 1 568 ? 138.522 131.675 88.404  1.00 59.71  ? 568 GLY A CA  1 
ATOM   3789 C  C   . GLY A 1 568 ? 139.974 131.445 88.771  1.00 59.71  ? 568 GLY A C   1 
ATOM   3790 O  O   . GLY A 1 568 ? 140.816 132.330 88.594  1.00 59.71  ? 568 GLY A O   1 
ATOM   3791 N  N   . ILE A 1 569 ? 140.288 130.259 89.293  1.00 61.02  ? 569 ILE A N   1 
ATOM   3792 C  CA  . ILE A 1 569 ? 141.675 129.929 89.600  1.00 61.02  ? 569 ILE A CA  1 
ATOM   3793 C  C   . ILE A 1 569 ? 142.509 129.905 88.327  1.00 61.02  ? 569 ILE A C   1 
ATOM   3794 O  O   . ILE A 1 569 ? 143.624 130.439 88.286  1.00 61.02  ? 569 ILE A O   1 
ATOM   3795 C  CB  . ILE A 1 569 ? 141.751 128.590 90.357  1.00 61.02  ? 569 ILE A CB  1 
ATOM   3796 C  CG1 . ILE A 1 569 ? 141.328 128.783 91.813  1.00 61.02  ? 569 ILE A CG1 1 
ATOM   3797 C  CG2 . ILE A 1 569 ? 143.153 128.006 90.286  1.00 61.02  ? 569 ILE A CG2 1 
ATOM   3798 C  CD1 . ILE A 1 569 ? 142.211 129.742 92.578  1.00 61.02  ? 569 ILE A CD1 1 
ATOM   3799 N  N   . CYS A 1 570 ? 141.979 129.297 87.263  1.00 63.02  ? 570 CYS A N   1 
ATOM   3800 C  CA  . CYS A 1 570 ? 142.749 129.178 86.029  1.00 63.02  ? 570 CYS A CA  1 
ATOM   3801 C  C   . CYS A 1 570 ? 142.960 130.529 85.354  1.00 63.02  ? 570 CYS A C   1 
ATOM   3802 O  O   . CYS A 1 570 ? 144.038 130.791 84.809  1.00 63.02  ? 570 CYS A O   1 
ATOM   3803 C  CB  . CYS A 1 570 ? 142.059 128.208 85.072  1.00 63.02  ? 570 CYS A CB  1 
ATOM   3804 S  SG  . CYS A 1 570 ? 142.361 126.465 85.429  1.00 63.02  ? 570 CYS A SG  1 
ATOM   3805 N  N   . THR A 1 571 ? 141.952 131.402 85.377  1.00 63.44  ? 571 THR A N   1 
ATOM   3806 C  CA  . THR A 1 571 ? 141.937 132.569 84.498  1.00 63.44  ? 571 THR A CA  1 
ATOM   3807 C  C   . THR A 1 571 ? 142.518 133.829 85.136  1.00 63.44  ? 571 THR A C   1 
ATOM   3808 O  O   . THR A 1 571 ? 143.526 134.354 84.654  1.00 63.44  ? 571 THR A O   1 
ATOM   3809 C  CB  . THR A 1 571 ? 140.504 132.836 84.018  1.00 63.44  ? 571 THR A CB  1 
ATOM   3810 O  OG1 . THR A 1 571 ? 139.626 132.900 85.147  1.00 63.44  ? 571 THR A OG1 1 
ATOM   3811 C  CG2 . THR A 1 571 ? 140.042 131.732 83.080  1.00 63.44  ? 571 THR A CG2 1 
ATOM   3812 N  N   . TRP A 1 572 ? 141.908 134.332 86.211  1.00 65.95  ? 572 TRP A N   1 
ATOM   3813 C  CA  . TRP A 1 572 ? 142.221 135.680 86.673  1.00 65.95  ? 572 TRP A CA  1 
ATOM   3814 C  C   . TRP A 1 572 ? 142.916 135.747 88.025  1.00 65.95  ? 572 TRP A C   1 
ATOM   3815 O  O   . TRP A 1 572 ? 143.573 136.750 88.309  1.00 65.95  ? 572 TRP A O   1 
ATOM   3816 C  CB  . TRP A 1 572 ? 140.946 136.538 86.724  1.00 65.95  ? 572 TRP A CB  1 
ATOM   3817 C  CG  . TRP A 1 572 ? 139.974 136.198 87.825  1.00 65.95  ? 572 TRP A CG  1 
ATOM   3818 C  CD1 . TRP A 1 572 ? 140.108 136.473 89.155  1.00 65.95  ? 572 TRP A CD1 1 
ATOM   3819 C  CD2 . TRP A 1 572 ? 138.707 135.543 87.680  1.00 65.95  ? 572 TRP A CD2 1 
ATOM   3820 N  NE1 . TRP A 1 572 ? 139.013 136.020 89.847  1.00 65.95  ? 572 TRP A NE1 1 
ATOM   3821 C  CE2 . TRP A 1 572 ? 138.138 135.445 88.965  1.00 65.95  ? 572 TRP A CE2 1 
ATOM   3822 C  CE3 . TRP A 1 572 ? 138.003 135.025 86.590  1.00 65.95  ? 572 TRP A CE3 1 
ATOM   3823 C  CZ2 . TRP A 1 572 ? 136.899 134.850 89.189  1.00 65.95  ? 572 TRP A CZ2 1 
ATOM   3824 C  CZ3 . TRP A 1 572 ? 136.773 134.434 86.815  1.00 65.95  ? 572 TRP A CZ3 1 
ATOM   3825 C  CH2 . TRP A 1 572 ? 136.233 134.352 88.104  1.00 65.95  ? 572 TRP A CH2 1 
ATOM   3826 N  N   . ILE A 1 573 ? 142.786 134.723 88.869  1.00 69.19  ? 573 ILE A N   1 
ATOM   3827 C  CA  . ILE A 1 573 ? 143.397 134.782 90.193  1.00 69.19  ? 573 ILE A CA  1 
ATOM   3828 C  C   . ILE A 1 573 ? 144.916 134.683 90.091  1.00 69.19  ? 573 ILE A C   1 
ATOM   3829 O  O   . ILE A 1 573 ? 145.650 135.378 90.809  1.00 69.19  ? 573 ILE A O   1 
ATOM   3830 C  CB  . ILE A 1 573 ? 142.806 133.684 91.095  1.00 69.19  ? 573 ILE A CB  1 
ATOM   3831 C  CG1 . ILE A 1 573 ? 141.391 134.069 91.527  1.00 69.19  ? 573 ILE A CG1 1 
ATOM   3832 C  CG2 . ILE A 1 573 ? 143.682 133.457 92.315  1.00 69.19  ? 573 ILE A CG2 1 
ATOM   3833 C  CD1 . ILE A 1 573 ? 140.585 132.929 92.103  1.00 69.19  ? 573 ILE A CD1 1 
ATOM   3834 N  N   . VAL A 1 574 ? 145.410 133.825 89.194  1.00 72.81  ? 574 VAL A N   1 
ATOM   3835 C  CA  . VAL A 1 574 ? 146.856 133.636 89.061  1.00 72.81  ? 574 VAL A CA  1 
ATOM   3836 C  C   . VAL A 1 574 ? 147.579 134.923 88.679  1.00 72.81  ? 574 VAL A C   1 
ATOM   3837 O  O   . VAL A 1 574 ? 148.607 135.233 89.303  1.00 72.81  ? 574 VAL A O   1 
ATOM   3838 C  CB  . VAL A 1 574 ? 147.149 132.480 88.087  1.00 72.81  ? 574 VAL A CB  1 
ATOM   3839 C  CG1 . VAL A 1 574 ? 148.612 132.491 87.675  1.00 72.81  ? 574 VAL A CG1 1 
ATOM   3840 C  CG2 . VAL A 1 574 ? 146.782 131.151 88.720  1.00 72.81  ? 574 VAL A CG2 1 
ATOM   3841 N  N   . PRO A 1 575 ? 147.125 135.706 87.689  1.00 73.24  ? 575 PRO A N   1 
ATOM   3842 C  CA  . PRO A 1 575 ? 147.837 136.963 87.396  1.00 73.24  ? 575 PRO A CA  1 
ATOM   3843 C  C   . PRO A 1 575 ? 147.929 137.897 88.589  1.00 73.24  ? 575 PRO A C   1 
ATOM   3844 O  O   . PRO A 1 575 ? 148.937 138.596 88.746  1.00 73.24  ? 575 PRO A O   1 
ATOM   3845 C  CB  . PRO A 1 575 ? 147.011 137.574 86.257  1.00 73.24  ? 575 PRO A CB  1 
ATOM   3846 C  CG  . PRO A 1 575 ? 146.387 136.416 85.591  1.00 73.24  ? 575 PRO A CG  1 
ATOM   3847 C  CD  . PRO A 1 575 ? 146.081 135.435 86.682  1.00 73.24  ? 575 PRO A CD  1 
ATOM   3848 N  N   . MET A 1 576 ? 146.902 137.929 89.440  1.00 72.92  ? 576 MET A N   1 
ATOM   3849 C  CA  . MET A 1 576 ? 146.951 138.799 90.610  1.00 72.92  ? 576 MET A CA  1 
ATOM   3850 C  C   . MET A 1 576 ? 147.895 138.250 91.671  1.00 72.92  ? 576 MET A C   1 
ATOM   3851 O  O   . MET A 1 576 ? 148.604 139.018 92.333  1.00 72.92  ? 576 MET A O   1 
ATOM   3852 C  CB  . MET A 1 576 ? 145.552 138.988 91.191  1.00 72.92  ? 576 MET A CB  1 
ATOM   3853 C  CG  . MET A 1 576 ? 144.598 139.750 90.290  1.00 72.92  ? 576 MET A CG  1 
ATOM   3854 S  SD  . MET A 1 576 ? 142.992 139.991 91.069  1.00 72.92  ? 576 MET A SD  1 
ATOM   3855 C  CE  . MET A 1 576 ? 142.316 138.340 90.944  1.00 72.92  ? 576 MET A CE  1 
ATOM   3856 N  N   . PHE A 1 577 ? 147.921 136.930 91.854  1.00 75.22  ? 577 PHE A N   1 
ATOM   3857 C  CA  . PHE A 1 577 ? 148.702 136.340 92.934  1.00 75.22  ? 577 PHE A CA  1 
ATOM   3858 C  C   . PHE A 1 577 ? 150.011 135.706 92.478  1.00 75.22  ? 577 PHE A C   1 
ATOM   3859 O  O   . PHE A 1 577 ? 150.818 135.327 93.334  1.00 75.22  ? 577 PHE A O   1 
ATOM   3860 C  CB  . PHE A 1 577 ? 147.865 135.296 93.682  1.00 75.22  ? 577 PHE A CB  1 
ATOM   3861 C  CG  . PHE A 1 577 ? 147.077 135.863 94.826  1.00 75.22  ? 577 PHE A CG  1 
ATOM   3862 C  CD1 . PHE A 1 577 ? 147.684 136.112 96.044  1.00 75.22  ? 577 PHE A CD1 1 
ATOM   3863 C  CD2 . PHE A 1 577 ? 145.733 136.154 94.681  1.00 75.22  ? 577 PHE A CD2 1 
ATOM   3864 C  CE1 . PHE A 1 577 ? 146.961 136.636 97.098  1.00 75.22  ? 577 PHE A CE1 1 
ATOM   3865 C  CE2 . PHE A 1 577 ? 145.007 136.677 95.731  1.00 75.22  ? 577 PHE A CE2 1 
ATOM   3866 C  CZ  . PHE A 1 577 ? 145.621 136.919 96.941  1.00 75.22  ? 577 PHE A CZ  1 
ATOM   3867 N  N   . ASP A 1 578 ? 150.246 135.592 91.170  1.00 78.16  ? 578 ASP A N   1 
ATOM   3868 C  CA  . ASP A 1 578 ? 151.461 134.975 90.633  1.00 78.16  ? 578 ASP A CA  1 
ATOM   3869 C  C   . ASP A 1 578 ? 151.657 133.571 91.203  1.00 78.16  ? 578 ASP A C   1 
ATOM   3870 O  O   . ASP A 1 578 ? 152.722 133.216 91.712  1.00 78.16  ? 578 ASP A O   1 
ATOM   3871 C  CB  . ASP A 1 578 ? 152.686 135.853 90.895  1.00 78.16  ? 578 ASP A CB  1 
ATOM   3872 C  CG  . ASP A 1 578 ? 153.794 135.623 89.886  1.00 78.16  ? 578 ASP A CG  1 
ATOM   3873 O  OD1 . ASP A 1 578 ? 153.566 134.877 88.911  1.00 78.16  ? 578 ASP A OD1 1 
ATOM   3874 O  OD2 . ASP A 1 578 ? 154.893 136.188 90.069  1.00 78.16  ? 578 ASP A OD2 1 
ATOM   3875 N  N   . LEU A 1 579 ? 150.600 132.764 91.112  1.00 74.88  ? 579 LEU A N   1 
ATOM   3876 C  CA  . LEU A 1 579 ? 150.582 131.460 91.761  1.00 74.88  ? 579 LEU A CA  1 
ATOM   3877 C  C   . LEU A 1 579 ? 151.387 130.402 91.018  1.00 74.88  ? 579 LEU A C   1 
ATOM   3878 O  O   . LEU A 1 579 ? 151.697 129.360 91.606  1.00 74.88  ? 579 LEU A O   1 
ATOM   3879 C  CB  . LEU A 1 579 ? 149.139 130.986 91.925  1.00 74.88  ? 579 LEU A CB  1 
ATOM   3880 C  CG  . LEU A 1 579 ? 148.282 131.822 92.877  1.00 74.88  ? 579 LEU A CG  1 
ATOM   3881 C  CD1 . LEU A 1 579 ? 146.834 131.362 92.868  1.00 74.88  ? 579 LEU A CD1 1 
ATOM   3882 C  CD2 . LEU A 1 579 ? 148.856 131.768 94.280  1.00 74.88  ? 579 LEU A CD2 1 
ATOM   3883 N  N   . TYR A 1 580 ? 151.720 130.628 89.745  1.00 79.89  ? 580 TYR A N   1 
ATOM   3884 C  CA  . TYR A 1 580 ? 152.504 129.642 89.007  1.00 79.89  ? 580 TYR A CA  1 
ATOM   3885 C  C   . TYR A 1 580 ? 153.903 129.489 89.592  1.00 79.89  ? 580 TYR A C   1 
ATOM   3886 O  O   . TYR A 1 580 ? 154.402 128.367 89.739  1.00 79.89  ? 580 TYR A O   1 
ATOM   3887 C  CB  . TYR A 1 580 ? 152.575 130.020 87.528  1.00 79.89  ? 580 TYR A CB  1 
ATOM   3888 C  CG  . TYR A 1 580 ? 151.255 129.905 86.802  1.00 79.89  ? 580 TYR A CG  1 
ATOM   3889 C  CD1 . TYR A 1 580 ? 150.191 129.210 87.361  1.00 79.89  ? 580 TYR A CD1 1 
ATOM   3890 C  CD2 . TYR A 1 580 ? 151.073 130.488 85.556  1.00 79.89  ? 580 TYR A CD2 1 
ATOM   3891 C  CE1 . TYR A 1 580 ? 148.985 129.097 86.700  1.00 79.89  ? 580 TYR A CE1 1 
ATOM   3892 C  CE2 . TYR A 1 580 ? 149.868 130.383 84.887  1.00 79.89  ? 580 TYR A CE2 1 
ATOM   3893 C  CZ  . TYR A 1 580 ? 148.828 129.687 85.464  1.00 79.89  ? 580 TYR A CZ  1 
ATOM   3894 O  OH  . TYR A 1 580 ? 147.627 129.580 84.801  1.00 79.89  ? 580 TYR A OH  1 
ATOM   3895 N  N   . THR A 1 581 ? 154.549 130.599 89.934  1.00 80.92  ? 581 THR A N   1 
ATOM   3896 C  CA  . THR A 1 581 ? 155.893 130.545 90.488  1.00 80.92  ? 581 THR A CA  1 
ATOM   3897 C  C   . THR A 1 581 ? 155.853 130.200 91.972  1.00 80.92  ? 581 THR A C   1 
ATOM   3898 O  O   . THR A 1 581 ? 154.863 130.450 92.666  1.00 80.92  ? 581 THR A O   1 
ATOM   3899 C  CB  . THR A 1 581 ? 156.618 131.876 90.281  1.00 80.92  ? 581 THR A CB  1 
ATOM   3900 O  OG1 . THR A 1 581 ? 157.973 131.759 90.733  1.00 80.92  ? 581 THR A OG1 1 
ATOM   3901 C  CG2 . THR A 1 581 ? 155.926 132.992 91.048  1.00 80.92  ? 581 THR A CG2 1 
ATOM   3902 N  N   . TYR A 1 582 ? 156.941 129.609 92.451  1.00 85.29  ? 582 TYR A N   1 
ATOM   3903 C  CA  . TYR A 1 582 ? 157.049 129.264 93.863  1.00 85.29  ? 582 TYR A CA  1 
ATOM   3904 C  C   . TYR A 1 582 ? 157.371 130.515 94.671  1.00 85.29  ? 582 TYR A C   1 
ATOM   3905 O  O   . TYR A 1 582 ? 158.358 131.196 94.370  1.00 85.29  ? 582 TYR A O   1 
ATOM   3906 C  CB  . TYR A 1 582 ? 158.120 128.203 94.077  1.00 85.29  ? 582 TYR A CB  1 
ATOM   3907 C  CG  . TYR A 1 582 ? 158.033 127.515 95.420  1.00 85.29  ? 582 TYR A CG  1 
ATOM   3908 C  CD1 . TYR A 1 582 ? 158.608 128.080 96.549  1.00 85.29  ? 582 TYR A CD1 1 
ATOM   3909 C  CD2 . TYR A 1 582 ? 157.370 126.305 95.559  1.00 85.29  ? 582 TYR A CD2 1 
ATOM   3910 C  CE1 . TYR A 1 582 ? 158.529 127.456 97.778  1.00 85.29  ? 582 TYR A CE1 1 
ATOM   3911 C  CE2 . TYR A 1 582 ? 157.285 125.674 96.784  1.00 85.29  ? 582 TYR A CE2 1 
ATOM   3912 C  CZ  . TYR A 1 582 ? 157.867 126.254 97.891  1.00 85.29  ? 582 TYR A CZ  1 
ATOM   3913 O  OH  . TYR A 1 582 ? 157.786 125.630 99.115  1.00 85.29  ? 582 TYR A OH  1 
ATOM   3914 N  N   . PRO A 1 583 ? 156.585 130.850 95.687  1.00 84.47  ? 583 PRO A N   1 
ATOM   3915 C  CA  . PRO A 1 583 ? 156.803 132.102 96.415  1.00 84.47  ? 583 PRO A CA  1 
ATOM   3916 C  C   . PRO A 1 583 ? 158.022 132.035 97.321  1.00 84.47  ? 583 PRO A C   1 
ATOM   3917 O  O   . PRO A 1 583 ? 158.494 130.966 97.710  1.00 84.47  ? 583 PRO A O   1 
ATOM   3918 C  CB  . PRO A 1 583 ? 155.519 132.255 97.235  1.00 84.47  ? 583 PRO A CB  1 
ATOM   3919 C  CG  . PRO A 1 583 ? 155.074 130.857 97.475  1.00 84.47  ? 583 PRO A CG  1 
ATOM   3920 C  CD  . PRO A 1 583 ? 155.485 130.057 96.263  1.00 84.47  ? 583 PRO A CD  1 
ATOM   3921 N  N   . SER A 1 584 ? 158.530 133.223 97.655  1.00 87.50  ? 584 SER A N   1 
ATOM   3922 C  CA  . SER A 1 584 ? 159.678 133.318 98.547  1.00 87.50  ? 584 SER A CA  1 
ATOM   3923 C  C   . SER A 1 584 ? 159.304 133.048 99.998  1.00 87.50  ? 584 SER A C   1 
ATOM   3924 O  O   . SER A 1 584 ? 160.148 132.584 100.773 1.00 87.50  ? 584 SER A O   1 
ATOM   3925 C  CB  . SER A 1 584 ? 160.326 134.698 98.423  1.00 87.50  ? 584 SER A CB  1 
ATOM   3926 O  OG  . SER A 1 584 ? 159.440 135.717 98.852  1.00 87.50  ? 584 SER A OG  1 
ATOM   3927 N  N   . TRP A 1 585 ? 158.058 133.333 100.388 1.00 85.54  ? 585 TRP A N   1 
ATOM   3928 C  CA  . TRP A 1 585 ? 157.661 133.126 101.777 1.00 85.54  ? 585 TRP A CA  1 
ATOM   3929 C  C   . TRP A 1 585 ? 157.549 131.646 102.120 1.00 85.54  ? 585 TRP A C   1 
ATOM   3930 O  O   . TRP A 1 585 ? 157.817 131.256 103.261 1.00 85.54  ? 585 TRP A O   1 
ATOM   3931 C  CB  . TRP A 1 585 ? 156.341 133.846 102.066 1.00 85.54  ? 585 TRP A CB  1 
ATOM   3932 C  CG  . TRP A 1 585 ? 155.142 133.293 101.348 1.00 85.54  ? 585 TRP A CG  1 
ATOM   3933 C  CD1 . TRP A 1 585 ? 154.434 132.171 101.674 1.00 85.54  ? 585 TRP A CD1 1 
ATOM   3934 C  CD2 . TRP A 1 585 ? 154.496 133.854 100.200 1.00 85.54  ? 585 TRP A CD2 1 
ATOM   3935 N  NE1 . TRP A 1 585 ? 153.397 131.993 100.792 1.00 85.54  ? 585 TRP A NE1 1 
ATOM   3936 C  CE2 . TRP A 1 585 ? 153.411 133.014 99.878  1.00 85.54  ? 585 TRP A CE2 1 
ATOM   3937 C  CE3 . TRP A 1 585 ? 154.731 134.983 99.409  1.00 85.54  ? 585 TRP A CE3 1 
ATOM   3938 C  CZ2 . TRP A 1 585 ? 152.565 133.266 98.801  1.00 85.54  ? 585 TRP A CZ2 1 
ATOM   3939 C  CZ3 . TRP A 1 585 ? 153.890 135.231 98.340  1.00 85.54  ? 585 TRP A CZ3 1 
ATOM   3940 C  CH2 . TRP A 1 585 ? 152.821 134.376 98.046  1.00 85.54  ? 585 TRP A CH2 1 
ATOM   3941 N  N   . ALA A 1 586 ? 157.154 130.817 101.160 1.00 86.01  ? 586 ALA A N   1 
ATOM   3942 C  CA  . ALA A 1 586 ? 157.019 129.393 101.422 1.00 86.01  ? 586 ALA A CA  1 
ATOM   3943 C  C   . ALA A 1 586 ? 158.394 128.766 101.641 1.00 86.01  ? 586 ALA A C   1 
ATOM   3944 O  O   . ALA A 1 586 ? 159.353 129.110 100.944 1.00 86.01  ? 586 ALA A O   1 
ATOM   3945 C  CB  . ALA A 1 586 ? 156.306 128.698 100.265 1.00 86.01  ? 586 ALA A CB  1 
ATOM   3946 N  N   . PRO A 1 587 ? 158.523 127.856 102.606 1.00 84.15  ? 587 PRO A N   1 
ATOM   3947 C  CA  . PRO A 1 587 ? 159.813 127.191 102.823 1.00 84.15  ? 587 PRO A CA  1 
ATOM   3948 C  C   . PRO A 1 587 ? 160.235 126.386 101.602 1.00 84.15  ? 587 PRO A C   1 
ATOM   3949 O  O   . PRO A 1 587 ? 159.403 125.829 100.882 1.00 84.15  ? 587 PRO A O   1 
ATOM   3950 C  CB  . PRO A 1 587 ? 159.545 126.284 104.030 1.00 84.15  ? 587 PRO A CB  1 
ATOM   3951 C  CG  . PRO A 1 587 ? 158.383 126.917 104.726 1.00 84.15  ? 587 PRO A CG  1 
ATOM   3952 C  CD  . PRO A 1 587 ? 157.534 127.498 103.635 1.00 84.15  ? 587 PRO A CD  1 
ATOM   3953 N  N   . ALA A 1 588 ? 161.544 126.331 101.376 1.00 82.19  ? 588 ALA A N   1 
ATOM   3954 C  CA  . ALA A 1 588 ? 162.099 125.614 100.233 1.00 82.19  ? 588 ALA A CA  1 
ATOM   3955 C  C   . ALA A 1 588 ? 161.874 124.111 100.363 1.00 82.19  ? 588 ALA A C   1 
ATOM   3956 O  O   . ALA A 1 588 ? 161.569 123.433 99.382  1.00 82.19  ? 588 ALA A O   1 
ATOM   3957 C  CB  . ALA A 1 588 ? 163.581 125.917 100.088 1.00 82.19  ? 588 ALA A CB  1 
ATOM   3958 N  N   . LYS B 1 2   ? 107.452 164.490 140.688 1.00 81.08  ? 2   LYS B N   1 
ATOM   3959 C  CA  . LYS B 1 2   ? 107.421 164.388 139.234 1.00 81.08  ? 2   LYS B CA  1 
ATOM   3960 C  C   . LYS B 1 2   ? 108.516 163.456 138.729 1.00 81.08  ? 2   LYS B C   1 
ATOM   3961 O  O   . LYS B 1 2   ? 108.240 162.346 138.273 1.00 81.08  ? 2   LYS B O   1 
ATOM   3962 C  CB  . LYS B 1 2   ? 107.569 165.771 138.595 1.00 81.08  ? 2   LYS B CB  1 
ATOM   3963 C  CG  . LYS B 1 2   ? 106.480 166.786 138.957 1.00 81.08  ? 2   LYS B CG  1 
ATOM   3964 C  CD  . LYS B 1 2   ? 105.127 166.470 138.315 1.00 81.08  ? 2   LYS B CD  1 
ATOM   3965 C  CE  . LYS B 1 2   ? 104.213 165.671 139.237 1.00 81.08  ? 2   LYS B CE  1 
ATOM   3966 N  NZ  . LYS B 1 2   ? 102.864 165.465 138.642 1.00 81.08  ? 2   LYS B NZ  1 
ATOM   3967 N  N   . PHE B 1 3   ? 109.766 163.916 138.816 1.00 81.44  ? 3   PHE B N   1 
ATOM   3968 C  CA  . PHE B 1 3   ? 110.892 163.109 138.364 1.00 81.44  ? 3   PHE B CA  1 
ATOM   3969 C  C   . PHE B 1 3   ? 111.153 161.918 139.275 1.00 81.44  ? 3   PHE B C   1 
ATOM   3970 O  O   . PHE B 1 3   ? 111.799 160.956 138.845 1.00 81.44  ? 3   PHE B O   1 
ATOM   3971 C  CB  . PHE B 1 3   ? 112.154 163.968 138.263 1.00 81.44  ? 3   PHE B CB  1 
ATOM   3972 C  CG  . PHE B 1 3   ? 112.104 164.998 137.169 1.00 81.44  ? 3   PHE B CG  1 
ATOM   3973 C  CD1 . PHE B 1 3   ? 111.145 164.928 136.170 1.00 81.44  ? 3   PHE B CD1 1 
ATOM   3974 C  CD2 . PHE B 1 3   ? 113.019 166.038 137.139 1.00 81.44  ? 3   PHE B CD2 1 
ATOM   3975 C  CE1 . PHE B 1 3   ? 111.099 165.875 135.164 1.00 81.44  ? 3   PHE B CE1 1 
ATOM   3976 C  CE2 . PHE B 1 3   ? 112.978 166.988 136.136 1.00 81.44  ? 3   PHE B CE2 1 
ATOM   3977 C  CZ  . PHE B 1 3   ? 112.017 166.906 135.147 1.00 81.44  ? 3   PHE B CZ  1 
ATOM   3978 N  N   . PHE B 1 4   ? 110.673 161.963 140.520 1.00 77.60  ? 4   PHE B N   1 
ATOM   3979 C  CA  . PHE B 1 4   ? 110.893 160.850 141.439 1.00 77.60  ? 4   PHE B CA  1 
ATOM   3980 C  C   . PHE B 1 4   ? 110.218 159.580 140.938 1.00 77.60  ? 4   PHE B C   1 
ATOM   3981 O  O   . PHE B 1 4   ? 110.793 158.488 141.023 1.00 77.60  ? 4   PHE B O   1 
ATOM   3982 C  CB  . PHE B 1 4   ? 110.389 161.218 142.834 1.00 77.60  ? 4   PHE B CB  1 
ATOM   3983 C  CG  . PHE B 1 4   ? 110.743 160.211 143.891 1.00 77.60  ? 4   PHE B CG  1 
ATOM   3984 C  CD1 . PHE B 1 4   ? 112.024 159.690 143.969 1.00 77.60  ? 4   PHE B CD1 1 
ATOM   3985 C  CD2 . PHE B 1 4   ? 109.797 159.790 144.811 1.00 77.60  ? 4   PHE B CD2 1 
ATOM   3986 C  CE1 . PHE B 1 4   ? 112.354 158.764 144.941 1.00 77.60  ? 4   PHE B CE1 1 
ATOM   3987 C  CE2 . PHE B 1 4   ? 110.121 158.865 145.785 1.00 77.60  ? 4   PHE B CE2 1 
ATOM   3988 C  CZ  . PHE B 1 4   ? 111.400 158.352 145.850 1.00 77.60  ? 4   PHE B CZ  1 
ATOM   3989 N  N   . SER B 1 5   ? 108.997 159.701 140.412 1.00 73.96  ? 5   SER B N   1 
ATOM   3990 C  CA  . SER B 1 5   ? 108.315 158.537 139.856 1.00 73.96  ? 5   SER B CA  1 
ATOM   3991 C  C   . SER B 1 5   ? 109.067 157.979 138.654 1.00 73.96  ? 5   SER B C   1 
ATOM   3992 O  O   . SER B 1 5   ? 109.180 156.757 138.494 1.00 73.96  ? 5   SER B O   1 
ATOM   3993 C  CB  . SER B 1 5   ? 106.882 158.904 139.469 1.00 73.96  ? 5   SER B CB  1 
ATOM   3994 O  OG  . SER B 1 5   ? 106.867 159.824 138.391 1.00 73.96  ? 5   SER B OG  1 
ATOM   3995 N  N   . TYR B 1 6   ? 109.584 158.860 137.795 1.00 70.01  ? 6   TYR B N   1 
ATOM   3996 C  CA  . TYR B 1 6   ? 110.321 158.405 136.621 1.00 70.01  ? 6   TYR B CA  1 
ATOM   3997 C  C   . TYR B 1 6   ? 111.625 157.725 137.017 1.00 70.01  ? 6   TYR B C   1 
ATOM   3998 O  O   . TYR B 1 6   ? 112.077 156.792 136.343 1.00 70.01  ? 6   TYR B O   1 
ATOM   3999 C  CB  . TYR B 1 6   ? 110.586 159.580 135.681 1.00 70.01  ? 6   TYR B CB  1 
ATOM   4000 C  CG  . TYR B 1 6   ? 109.475 159.823 134.686 1.00 70.01  ? 6   TYR B CG  1 
ATOM   4001 C  CD1 . TYR B 1 6   ? 108.261 159.160 134.798 1.00 70.01  ? 6   TYR B CD1 1 
ATOM   4002 C  CD2 . TYR B 1 6   ? 109.641 160.714 133.635 1.00 70.01  ? 6   TYR B CD2 1 
ATOM   4003 C  CE1 . TYR B 1 6   ? 107.242 159.378 133.891 1.00 70.01  ? 6   TYR B CE1 1 
ATOM   4004 C  CE2 . TYR B 1 6   ? 108.628 160.939 132.723 1.00 70.01  ? 6   TYR B CE2 1 
ATOM   4005 C  CZ  . TYR B 1 6   ? 107.431 160.268 132.857 1.00 70.01  ? 6   TYR B CZ  1 
ATOM   4006 O  OH  . TYR B 1 6   ? 106.419 160.488 131.951 1.00 70.01  ? 6   TYR B OH  1 
ATOM   4007 N  N   . ILE B 1 7   ? 112.254 158.187 138.098 1.00 65.24  ? 7   ILE B N   1 
ATOM   4008 C  CA  . ILE B 1 7   ? 113.450 157.515 138.594 1.00 65.24  ? 7   ILE B CA  1 
ATOM   4009 C  C   . ILE B 1 7   ? 113.092 156.157 139.183 1.00 65.24  ? 7   ILE B C   1 
ATOM   4010 O  O   . ILE B 1 7   ? 113.804 155.167 138.978 1.00 65.24  ? 7   ILE B O   1 
ATOM   4011 C  CB  . ILE B 1 7   ? 114.180 158.406 139.615 1.00 65.24  ? 7   ILE B CB  1 
ATOM   4012 C  CG1 . ILE B 1 7   ? 114.764 159.640 138.925 1.00 65.24  ? 7   ILE B CG1 1 
ATOM   4013 C  CG2 . ILE B 1 7   ? 115.274 157.627 140.325 1.00 65.24  ? 7   ILE B CG2 1 
ATOM   4014 C  CD1 . ILE B 1 7   ? 115.489 159.336 137.632 1.00 65.24  ? 7   ILE B CD1 1 
ATOM   4015 N  N   . LEU B 1 8   ? 111.982 156.086 139.921 1.00 63.04  ? 8   LEU B N   1 
ATOM   4016 C  CA  . LEU B 1 8   ? 111.588 154.828 140.546 1.00 63.04  ? 8   LEU B CA  1 
ATOM   4017 C  C   . LEU B 1 8   ? 111.219 153.772 139.511 1.00 63.04  ? 8   LEU B C   1 
ATOM   4018 O  O   . LEU B 1 8   ? 111.568 152.597 139.669 1.00 63.04  ? 8   LEU B O   1 
ATOM   4019 C  CB  . LEU B 1 8   ? 110.424 155.063 141.508 1.00 63.04  ? 8   LEU B CB  1 
ATOM   4020 C  CG  . LEU B 1 8   ? 110.783 155.688 142.857 1.00 63.04  ? 8   LEU B CG  1 
ATOM   4021 C  CD1 . LEU B 1 8   ? 109.528 155.981 143.662 1.00 63.04  ? 8   LEU B CD1 1 
ATOM   4022 C  CD2 . LEU B 1 8   ? 111.722 154.778 143.633 1.00 63.04  ? 8   LEU B CD2 1 
ATOM   4023 N  N   . VAL B 1 9   ? 110.508 154.164 138.451 1.00 54.60  ? 9   VAL B N   1 
ATOM   4024 C  CA  . VAL B 1 9   ? 110.035 153.177 137.483 1.00 54.60  ? 9   VAL B CA  1 
ATOM   4025 C  C   . VAL B 1 9   ? 111.203 152.552 136.726 1.00 54.60  ? 9   VAL B C   1 
ATOM   4026 O  O   . VAL B 1 9   ? 111.257 151.329 136.550 1.00 54.60  ? 9   VAL B O   1 
ATOM   4027 C  CB  . VAL B 1 9   ? 108.989 153.802 136.537 1.00 54.60  ? 9   VAL B CB  1 
ATOM   4028 C  CG1 . VAL B 1 9   ? 109.557 154.983 135.776 1.00 54.60  ? 9   VAL B CG1 1 
ATOM   4029 C  CG2 . VAL B 1 9   ? 108.457 152.762 135.568 1.00 54.60  ? 9   VAL B CG2 1 
ATOM   4030 N  N   . TYR B 1 10  ? 112.154 153.364 136.272 1.00 44.22  ? 10  TYR B N   1 
ATOM   4031 C  CA  . TYR B 1 10  ? 113.335 152.854 135.574 1.00 44.22  ? 10  TYR B CA  1 
ATOM   4032 C  C   . TYR B 1 10  ? 114.529 152.724 136.514 1.00 44.22  ? 10  TYR B C   1 
ATOM   4033 O  O   . TYR B 1 10  ? 115.591 153.293 136.275 1.00 44.22  ? 10  TYR B O   1 
ATOM   4034 C  CB  . TYR B 1 10  ? 113.672 153.755 134.392 1.00 44.22  ? 10  TYR B CB  1 
ATOM   4035 C  CG  . TYR B 1 10  ? 112.582 153.844 133.350 1.00 44.22  ? 10  TYR B CG  1 
ATOM   4036 C  CD1 . TYR B 1 10  ? 112.253 152.750 132.566 1.00 44.22  ? 10  TYR B CD1 1 
ATOM   4037 C  CD2 . TYR B 1 10  ? 111.890 155.029 133.144 1.00 44.22  ? 10  TYR B CD2 1 
ATOM   4038 C  CE1 . TYR B 1 10  ? 111.258 152.829 131.612 1.00 44.22  ? 10  TYR B CE1 1 
ATOM   4039 C  CE2 . TYR B 1 10  ? 110.894 155.118 132.193 1.00 44.22  ? 10  TYR B CE2 1 
ATOM   4040 C  CZ  . TYR B 1 10  ? 110.584 154.015 131.430 1.00 44.22  ? 10  TYR B CZ  1 
ATOM   4041 O  OH  . TYR B 1 10  ? 109.594 154.099 130.479 1.00 44.22  ? 10  TYR B OH  1 
ATOM   4042 N  N   . ARG B 1 11  ? 114.369 151.966 137.599 1.00 40.78  ? 11  ARG B N   1 
ATOM   4043 C  CA  . ARG B 1 11  ? 115.457 151.842 138.562 1.00 40.78  ? 11  ARG B CA  1 
ATOM   4044 C  C   . ARG B 1 11  ? 116.548 150.894 138.081 1.00 40.78  ? 11  ARG B C   1 
ATOM   4045 O  O   . ARG B 1 11  ? 117.725 151.118 138.380 1.00 40.78  ? 11  ARG B O   1 
ATOM   4046 C  CB  . ARG B 1 11  ? 114.916 151.395 139.923 1.00 40.78  ? 11  ARG B CB  1 
ATOM   4047 C  CG  . ARG B 1 11  ? 114.533 149.927 140.019 1.00 40.78  ? 11  ARG B CG  1 
ATOM   4048 C  CD  . ARG B 1 11  ? 114.694 149.405 141.439 1.00 40.78  ? 11  ARG B CD  1 
ATOM   4049 N  NE  . ARG B 1 11  ? 116.094 149.340 141.843 1.00 40.78  ? 11  ARG B NE  1 
ATOM   4050 C  CZ  . ARG B 1 11  ? 116.816 148.228 141.876 1.00 40.78  ? 11  ARG B CZ  1 
ATOM   4051 N  NH1 . ARG B 1 11  ? 116.301 147.059 141.533 1.00 40.78  ? 11  ARG B NH1 1 
ATOM   4052 N  NH2 . ARG B 1 11  ? 118.087 148.291 142.263 1.00 40.78  ? 11  ARG B NH2 1 
ATOM   4053 N  N   . ARG B 1 12  ? 116.193 149.850 137.329 1.00 33.68  ? 12  ARG B N   1 
ATOM   4054 C  CA  . ARG B 1 12  ? 117.191 148.873 136.902 1.00 33.68  ? 12  ARG B CA  1 
ATOM   4055 C  C   . ARG B 1 12  ? 118.134 149.459 135.858 1.00 33.68  ? 12  ARG B C   1 
ATOM   4056 O  O   . ARG B 1 12  ? 119.357 149.309 135.959 1.00 33.68  ? 12  ARG B O   1 
ATOM   4057 C  CB  . ARG B 1 12  ? 116.498 147.623 136.363 1.00 33.68  ? 12  ARG B CB  1 
ATOM   4058 C  CG  . ARG B 1 12  ? 115.312 147.169 137.191 1.00 33.68  ? 12  ARG B CG  1 
ATOM   4059 C  CD  . ARG B 1 12  ? 115.207 145.657 137.201 1.00 33.68  ? 12  ARG B CD  1 
ATOM   4060 N  NE  . ARG B 1 12  ? 115.598 145.088 135.918 1.00 33.68  ? 12  ARG B NE  1 
ATOM   4061 C  CZ  . ARG B 1 12  ? 114.768 144.887 134.904 1.00 33.68  ? 12  ARG B CZ  1 
ATOM   4062 N  NH1 . ARG B 1 12  ? 113.485 145.197 134.990 1.00 33.68  ? 12  ARG B NH1 1 
ATOM   4063 N  NH2 . ARG B 1 12  ? 115.237 144.365 133.775 1.00 33.68  ? 12  ARG B NH2 1 
ATOM   4064 N  N   . PHE B 1 13  ? 117.583 150.127 134.842 1.00 26.87  ? 13  PHE B N   1 
ATOM   4065 C  CA  . PHE B 1 13  ? 118.413 150.745 133.812 1.00 26.87  ? 13  PHE B CA  1 
ATOM   4066 C  C   . PHE B 1 13  ? 119.316 151.817 134.409 1.00 26.87  ? 13  PHE B C   1 
ATOM   4067 O  O   . PHE B 1 13  ? 120.520 151.878 134.115 1.00 26.87  ? 13  PHE B O   1 
ATOM   4068 C  CB  . PHE B 1 13  ? 117.509 151.330 132.723 1.00 26.87  ? 13  PHE B CB  1 
ATOM   4069 C  CG  . PHE B 1 13  ? 118.247 151.989 131.594 1.00 26.87  ? 13  PHE B CG  1 
ATOM   4070 C  CD1 . PHE B 1 13  ? 118.603 153.325 131.666 1.00 26.87  ? 13  PHE B CD1 1 
ATOM   4071 C  CD2 . PHE B 1 13  ? 118.568 151.279 130.453 1.00 26.87  ? 13  PHE B CD2 1 
ATOM   4072 C  CE1 . PHE B 1 13  ? 119.275 153.934 130.628 1.00 26.87  ? 13  PHE B CE1 1 
ATOM   4073 C  CE2 . PHE B 1 13  ? 119.240 151.885 129.411 1.00 26.87  ? 13  PHE B CE2 1 
ATOM   4074 C  CZ  . PHE B 1 13  ? 119.594 153.213 129.500 1.00 26.87  ? 13  PHE B CZ  1 
ATOM   4075 N  N   . LEU B 1 14  ? 118.745 152.670 135.263 1.00 27.91  ? 14  LEU B N   1 
ATOM   4076 C  CA  . LEU B 1 14  ? 119.526 153.724 135.896 1.00 27.91  ? 14  LEU B CA  1 
ATOM   4077 C  C   . LEU B 1 14  ? 120.621 153.139 136.774 1.00 27.91  ? 14  LEU B C   1 
ATOM   4078 O  O   . LEU B 1 14  ? 121.750 153.637 136.778 1.00 27.91  ? 14  LEU B O   1 
ATOM   4079 C  CB  . LEU B 1 14  ? 118.614 154.641 136.710 1.00 27.91  ? 14  LEU B CB  1 
ATOM   4080 C  CG  . LEU B 1 14  ? 118.090 155.907 136.027 1.00 27.91  ? 14  LEU B CG  1 
ATOM   4081 C  CD1 . LEU B 1 14  ? 119.234 156.856 135.722 1.00 27.91  ? 14  LEU B CD1 1 
ATOM   4082 C  CD2 . LEU B 1 14  ? 117.323 155.577 134.760 1.00 27.91  ? 14  LEU B CD2 1 
ATOM   4083 N  N   . PHE B 1 15  ? 120.311 152.077 137.522 1.00 25.90  ? 15  PHE B N   1 
ATOM   4084 C  CA  . PHE B 1 15  ? 121.327 151.454 138.361 1.00 25.90  ? 15  PHE B CA  1 
ATOM   4085 C  C   . PHE B 1 15  ? 122.434 150.827 137.525 1.00 25.90  ? 15  PHE B C   1 
ATOM   4086 O  O   . PHE B 1 15  ? 123.609 150.903 137.895 1.00 25.90  ? 15  PHE B O   1 
ATOM   4087 C  CB  . PHE B 1 15  ? 120.705 150.404 139.275 1.00 25.90  ? 15  PHE B CB  1 
ATOM   4088 C  CG  . PHE B 1 15  ? 121.707 149.702 140.142 1.00 25.90  ? 15  PHE B CG  1 
ATOM   4089 C  CD1 . PHE B 1 15  ? 122.263 150.342 141.235 1.00 25.90  ? 15  PHE B CD1 1 
ATOM   4090 C  CD2 . PHE B 1 15  ? 122.114 148.414 139.849 1.00 25.90  ? 15  PHE B CD2 1 
ATOM   4091 C  CE1 . PHE B 1 15  ? 123.194 149.702 142.030 1.00 25.90  ? 15  PHE B CE1 1 
ATOM   4092 C  CE2 . PHE B 1 15  ? 123.046 147.772 140.638 1.00 25.90  ? 15  PHE B CE2 1 
ATOM   4093 C  CZ  . PHE B 1 15  ? 123.584 148.416 141.730 1.00 25.90  ? 15  PHE B CZ  1 
ATOM   4094 N  N   . VAL B 1 16  ? 122.082 150.186 136.408 1.00 22.70  ? 16  VAL B N   1 
ATOM   4095 C  CA  . VAL B 1 16  ? 123.099 149.582 135.550 1.00 22.70  ? 16  VAL B CA  1 
ATOM   4096 C  C   . VAL B 1 16  ? 124.048 150.652 135.029 1.00 22.70  ? 16  VAL B C   1 
ATOM   4097 O  O   . VAL B 1 16  ? 125.276 150.516 135.110 1.00 22.70  ? 16  VAL B O   1 
ATOM   4098 C  CB  . VAL B 1 16  ? 122.441 148.806 134.396 1.00 22.70  ? 16  VAL B CB  1 
ATOM   4099 C  CG1 . VAL B 1 16  ? 123.459 148.508 133.310 1.00 22.70  ? 16  VAL B CG1 1 
ATOM   4100 C  CG2 . VAL B 1 16  ? 121.818 147.524 134.905 1.00 22.70  ? 16  VAL B CG2 1 
ATOM   4101 N  N   . VAL B 1 17  ? 123.489 151.748 134.509 1.00 25.22  ? 17  VAL B N   1 
ATOM   4102 C  CA  . VAL B 1 17  ? 124.331 152.825 133.992 1.00 25.22  ? 17  VAL B CA  1 
ATOM   4103 C  C   . VAL B 1 17  ? 125.176 153.427 135.110 1.00 25.22  ? 17  VAL B C   1 
ATOM   4104 O  O   . VAL B 1 17  ? 126.377 153.681 134.936 1.00 25.22  ? 17  VAL B O   1 
ATOM   4105 C  CB  . VAL B 1 17  ? 123.466 153.889 133.294 1.00 25.22  ? 17  VAL B CB  1 
ATOM   4106 C  CG1 . VAL B 1 17  ? 124.270 155.153 133.049 1.00 25.22  ? 17  VAL B CG1 1 
ATOM   4107 C  CG2 . VAL B 1 17  ? 122.919 153.345 131.987 1.00 25.22  ? 17  VAL B CG2 1 
ATOM   4108 N  N   . PHE B 1 18  ? 124.569 153.653 136.278 1.00 26.99  ? 18  PHE B N   1 
ATOM   4109 C  CA  . PHE B 1 18  ? 125.281 154.283 137.382 1.00 26.99  ? 18  PHE B CA  1 
ATOM   4110 C  C   . PHE B 1 18  ? 126.430 153.417 137.874 1.00 26.99  ? 18  PHE B C   1 
ATOM   4111 O  O   . PHE B 1 18  ? 127.516 153.928 138.155 1.00 26.99  ? 18  PHE B O   1 
ATOM   4112 C  CB  . PHE B 1 18  ? 124.316 154.580 138.527 1.00 26.99  ? 18  PHE B CB  1 
ATOM   4113 C  CG  . PHE B 1 18  ? 124.999 154.973 139.804 1.00 26.99  ? 18  PHE B CG  1 
ATOM   4114 C  CD1 . PHE B 1 18  ? 125.670 156.179 139.903 1.00 26.99  ? 18  PHE B CD1 1 
ATOM   4115 C  CD2 . PHE B 1 18  ? 124.978 154.133 140.903 1.00 26.99  ? 18  PHE B CD2 1 
ATOM   4116 C  CE1 . PHE B 1 18  ? 126.302 156.542 141.076 1.00 26.99  ? 18  PHE B CE1 1 
ATOM   4117 C  CE2 . PHE B 1 18  ? 125.609 154.490 142.078 1.00 26.99  ? 18  PHE B CE2 1 
ATOM   4118 C  CZ  . PHE B 1 18  ? 126.272 155.697 142.164 1.00 26.99  ? 18  PHE B CZ  1 
ATOM   4119 N  N   . THR B 1 19  ? 126.211 152.109 138.005 1.00 23.81  ? 19  THR B N   1 
ATOM   4120 C  CA  . THR B 1 19  ? 127.273 151.235 138.484 1.00 23.81  ? 19  THR B CA  1 
ATOM   4121 C  C   . THR B 1 19  ? 128.326 150.960 137.421 1.00 23.81  ? 19  THR B C   1 
ATOM   4122 O  O   . THR B 1 19  ? 129.457 150.609 137.771 1.00 23.81  ? 19  THR B O   1 
ATOM   4123 C  CB  . THR B 1 19  ? 126.699 149.914 138.998 1.00 23.81  ? 19  THR B CB  1 
ATOM   4124 O  OG1 . THR B 1 19  ? 127.706 149.213 139.736 1.00 23.81  ? 19  THR B OG1 1 
ATOM   4125 C  CG2 . THR B 1 19  ? 126.252 149.049 137.852 1.00 23.81  ? 19  THR B CG2 1 
ATOM   4126 N  N   . VAL B 1 20  ? 127.987 151.099 136.138 1.00 23.66  ? 20  VAL B N   1 
ATOM   4127 C  CA  . VAL B 1 20  ? 129.020 151.031 135.111 1.00 23.66  ? 20  VAL B CA  1 
ATOM   4128 C  C   . VAL B 1 20  ? 129.900 152.274 135.164 1.00 23.66  ? 20  VAL B C   1 
ATOM   4129 O  O   . VAL B 1 20  ? 131.129 152.185 135.064 1.00 23.66  ? 20  VAL B O   1 
ATOM   4130 C  CB  . VAL B 1 20  ? 128.386 150.836 133.723 1.00 23.66  ? 20  VAL B CB  1 
ATOM   4131 C  CG1 . VAL B 1 20  ? 129.363 151.233 132.630 1.00 23.66  ? 20  VAL B CG1 1 
ATOM   4132 C  CG2 . VAL B 1 20  ? 127.950 149.394 133.543 1.00 23.66  ? 20  VAL B CG2 1 
ATOM   4133 N  N   . LEU B 1 21  ? 129.290 153.449 135.334 1.00 25.15  ? 21  LEU B N   1 
ATOM   4134 C  CA  . LEU B 1 21  ? 130.054 154.693 135.299 1.00 25.15  ? 21  LEU B CA  1 
ATOM   4135 C  C   . LEU B 1 21  ? 130.803 154.973 136.599 1.00 25.15  ? 21  LEU B C   1 
ATOM   4136 O  O   . LEU B 1 21  ? 131.877 155.581 136.564 1.00 25.15  ? 21  LEU B O   1 
ATOM   4137 C  CB  . LEU B 1 21  ? 129.128 155.864 134.970 1.00 25.15  ? 21  LEU B CB  1 
ATOM   4138 C  CG  . LEU B 1 21  ? 128.423 155.793 133.614 1.00 25.15  ? 21  LEU B CG  1 
ATOM   4139 C  CD1 . LEU B 1 21  ? 127.696 157.092 133.312 1.00 25.15  ? 21  LEU B CD1 1 
ATOM   4140 C  CD2 . LEU B 1 21  ? 129.413 155.463 132.512 1.00 25.15  ? 21  LEU B CD2 1 
ATOM   4141 N  N   . VAL B 1 22  ? 130.259 154.566 137.748 1.00 26.73  ? 22  VAL B N   1 
ATOM   4142 C  CA  . VAL B 1 22  ? 130.870 154.933 139.023 1.00 26.73  ? 22  VAL B CA  1 
ATOM   4143 C  C   . VAL B 1 22  ? 132.151 154.145 139.264 1.00 26.73  ? 22  VAL B C   1 
ATOM   4144 O  O   . VAL B 1 22  ? 133.097 154.661 139.871 1.00 26.73  ? 22  VAL B O   1 
ATOM   4145 C  CB  . VAL B 1 22  ? 129.867 154.757 140.180 1.00 26.73  ? 22  VAL B CB  1 
ATOM   4146 C  CG1 . VAL B 1 22  ? 129.607 153.287 140.469 1.00 26.73  ? 22  VAL B CG1 1 
ATOM   4147 C  CG2 . VAL B 1 22  ? 130.368 155.466 141.425 1.00 26.73  ? 22  VAL B CG2 1 
ATOM   4148 N  N   . LEU B 1 23  ? 132.209 152.897 138.810 1.00 25.49  ? 23  LEU B N   1 
ATOM   4149 C  CA  . LEU B 1 23  ? 133.423 152.099 138.899 1.00 25.49  ? 23  LEU B CA  1 
ATOM   4150 C  C   . LEU B 1 23  ? 134.349 152.330 137.717 1.00 25.49  ? 23  LEU B C   1 
ATOM   4151 O  O   . LEU B 1 23  ? 135.452 151.776 137.692 1.00 25.49  ? 23  LEU B O   1 
ATOM   4152 C  CB  . LEU B 1 23  ? 133.070 150.612 139.000 1.00 25.49  ? 23  LEU B CB  1 
ATOM   4153 C  CG  . LEU B 1 23  ? 132.546 150.129 140.351 1.00 25.49  ? 23  LEU B CG  1 
ATOM   4154 C  CD1 . LEU B 1 23  ? 131.599 148.958 140.166 1.00 25.49  ? 23  LEU B CD1 1 
ATOM   4155 C  CD2 . LEU B 1 23  ? 133.697 149.747 141.262 1.00 25.49  ? 23  LEU B CD2 1 
ATOM   4156 N  N   . LEU B 1 24  ? 133.919 153.132 136.745 1.00 28.25  ? 24  LEU B N   1 
ATOM   4157 C  CA  . LEU B 1 24  ? 134.765 153.438 135.599 1.00 28.25  ? 24  LEU B CA  1 
ATOM   4158 C  C   . LEU B 1 24  ? 136.112 154.059 135.961 1.00 28.25  ? 24  LEU B C   1 
ATOM   4159 O  O   . LEU B 1 24  ? 137.091 153.747 135.265 1.00 28.25  ? 24  LEU B O   1 
ATOM   4160 C  CB  . LEU B 1 24  ? 134.006 154.347 134.622 1.00 28.25  ? 24  LEU B CB  1 
ATOM   4161 C  CG  . LEU B 1 24  ? 134.513 154.352 133.180 1.00 28.25  ? 24  LEU B CG  1 
ATOM   4162 C  CD1 . LEU B 1 24  ? 134.829 152.941 132.720 1.00 28.25  ? 24  LEU B CD1 1 
ATOM   4163 C  CD2 . LEU B 1 24  ? 133.488 154.996 132.264 1.00 28.25  ? 24  LEU B CD2 1 
ATOM   4164 N  N   . PRO B 1 25  ? 136.243 154.935 136.965 1.00 28.16  ? 25  PRO B N   1 
ATOM   4165 C  CA  . PRO B 1 25  ? 137.581 155.468 137.275 1.00 28.16  ? 25  PRO B CA  1 
ATOM   4166 C  C   . PRO B 1 25  ? 138.606 154.404 137.627 1.00 28.16  ? 25  PRO B C   1 
ATOM   4167 O  O   . PRO B 1 25  ? 139.808 154.655 137.482 1.00 28.16  ? 25  PRO B O   1 
ATOM   4168 C  CB  . PRO B 1 25  ? 137.321 156.408 138.464 1.00 28.16  ? 25  PRO B CB  1 
ATOM   4169 C  CG  . PRO B 1 25  ? 135.931 156.103 138.924 1.00 28.16  ? 25  PRO B CG  1 
ATOM   4170 C  CD  . PRO B 1 25  ? 135.206 155.672 137.701 1.00 28.16  ? 25  PRO B CD  1 
ATOM   4171 N  N   . LEU B 1 26  ? 138.180 153.232 138.096 1.00 26.99  ? 26  LEU B N   1 
ATOM   4172 C  CA  . LEU B 1 26  ? 139.143 152.213 138.514 1.00 26.99  ? 26  LEU B CA  1 
ATOM   4173 C  C   . LEU B 1 26  ? 140.080 151.783 137.390 1.00 26.99  ? 26  LEU B C   1 
ATOM   4174 O  O   . LEU B 1 26  ? 141.297 151.713 137.630 1.00 26.99  ? 26  LEU B O   1 
ATOM   4175 C  CB  . LEU B 1 26  ? 138.399 151.021 139.127 1.00 26.99  ? 26  LEU B CB  1 
ATOM   4176 C  CG  . LEU B 1 26  ? 139.236 150.004 139.903 1.00 26.99  ? 26  LEU B CG  1 
ATOM   4177 C  CD1 . LEU B 1 26  ? 140.210 150.710 140.830 1.00 26.99  ? 26  LEU B CD1 1 
ATOM   4178 C  CD2 . LEU B 1 26  ? 138.343 149.056 140.681 1.00 26.99  ? 26  LEU B CD2 1 
ATOM   4179 N  N   . PRO B 1 27  ? 139.613 151.478 136.163 1.00 27.11  ? 27  PRO B N   1 
ATOM   4180 C  CA  . PRO B 1 27  ? 140.568 151.192 135.081 1.00 27.11  ? 27  PRO B CA  1 
ATOM   4181 C  C   . PRO B 1 27  ? 141.447 152.367 134.671 1.00 27.11  ? 27  PRO B C   1 
ATOM   4182 O  O   . PRO B 1 27  ? 142.665 152.193 134.579 1.00 27.11  ? 27  PRO B O   1 
ATOM   4183 C  CB  . PRO B 1 27  ? 139.661 150.749 133.927 1.00 27.11  ? 27  PRO B CB  1 
ATOM   4184 C  CG  . PRO B 1 27  ? 138.474 150.195 134.595 1.00 27.11  ? 27  PRO B CG  1 
ATOM   4185 C  CD  . PRO B 1 27  ? 138.250 151.063 135.787 1.00 27.11  ? 27  PRO B CD  1 
ATOM   4186 N  N   . ILE B 1 28  ? 140.876 153.550 134.411 1.00 32.68  ? 28  ILE B N   1 
ATOM   4187 C  CA  . ILE B 1 28  ? 141.690 154.661 133.912 1.00 32.68  ? 28  ILE B CA  1 
ATOM   4188 C  C   . ILE B 1 28  ? 142.738 155.078 134.938 1.00 32.68  ? 28  ILE B C   1 
ATOM   4189 O  O   . ILE B 1 28  ? 143.915 155.255 134.604 1.00 32.68  ? 28  ILE B O   1 
ATOM   4190 C  CB  . ILE B 1 28  ? 140.812 155.852 133.483 1.00 32.68  ? 28  ILE B CB  1 
ATOM   4191 C  CG1 . ILE B 1 28  ? 139.724 155.413 132.501 1.00 32.68  ? 28  ILE B CG1 1 
ATOM   4192 C  CG2 . ILE B 1 28  ? 141.670 156.947 132.873 1.00 32.68  ? 28  ILE B CG2 1 
ATOM   4193 C  CD1 . ILE B 1 28  ? 138.358 155.319 133.083 1.00 32.68  ? 28  ILE B CD1 1 
ATOM   4194 N  N   . VAL B 1 29  ? 142.336 155.248 136.196 1.00 35.63  ? 29  VAL B N   1 
ATOM   4195 C  CA  . VAL B 1 29  ? 143.300 155.506 137.257 1.00 35.63  ? 29  VAL B CA  1 
ATOM   4196 C  C   . VAL B 1 29  ? 144.025 154.187 137.502 1.00 35.63  ? 29  VAL B C   1 
ATOM   4197 O  O   . VAL B 1 29  ? 143.598 153.141 137.000 1.00 35.63  ? 29  VAL B O   1 
ATOM   4198 C  CB  . VAL B 1 29  ? 142.601 156.047 138.522 1.00 35.63  ? 29  VAL B CB  1 
ATOM   4199 C  CG1 . VAL B 1 29  ? 143.606 156.475 139.583 1.00 35.63  ? 29  VAL B CG1 1 
ATOM   4200 C  CG2 . VAL B 1 29  ? 141.688 157.209 138.164 1.00 35.63  ? 29  VAL B CG2 1 
ATOM   4201 N  N   . LEU B 1 30  ? 145.139 154.227 138.235 1.00 43.94  ? 30  LEU B N   1 
ATOM   4202 C  CA  . LEU B 1 30  ? 145.970 153.065 138.543 1.00 43.94  ? 30  LEU B CA  1 
ATOM   4203 C  C   . LEU B 1 30  ? 146.734 152.556 137.327 1.00 43.94  ? 30  LEU B C   1 
ATOM   4204 O  O   . LEU B 1 30  ? 147.227 151.424 137.334 1.00 43.94  ? 30  LEU B O   1 
ATOM   4205 C  CB  . LEU B 1 30  ? 145.149 151.923 139.160 1.00 43.94  ? 30  LEU B CB  1 
ATOM   4206 C  CG  . LEU B 1 30  ? 144.956 151.904 140.678 1.00 43.94  ? 30  LEU B CG  1 
ATOM   4207 C  CD1 . LEU B 1 30  ? 144.220 153.142 141.158 1.00 43.94  ? 30  LEU B CD1 1 
ATOM   4208 C  CD2 . LEU B 1 30  ? 144.208 150.650 141.090 1.00 43.94  ? 30  LEU B CD2 1 
ATOM   4209 N  N   . HIS B 1 31  ? 146.830 153.371 136.275 1.00 49.93  ? 31  HIS B N   1 
ATOM   4210 C  CA  . HIS B 1 31  ? 147.674 153.116 135.108 1.00 49.93  ? 31  HIS B CA  1 
ATOM   4211 C  C   . HIS B 1 31  ? 147.300 151.834 134.368 1.00 49.93  ? 31  HIS B C   1 
ATOM   4212 O  O   . HIS B 1 31  ? 148.095 151.330 133.568 1.00 49.93  ? 31  HIS B O   1 
ATOM   4213 C  CB  . HIS B 1 31  ? 149.158 153.083 135.493 1.00 49.93  ? 31  HIS B CB  1 
ATOM   4214 C  CG  . HIS B 1 31  ? 149.570 154.193 136.410 1.00 49.93  ? 31  HIS B CG  1 
ATOM   4215 N  ND1 . HIS B 1 31  ? 149.811 153.998 137.753 1.00 49.93  ? 31  HIS B ND1 1 
ATOM   4216 C  CD2 . HIS B 1 31  ? 149.786 155.509 136.177 1.00 49.93  ? 31  HIS B CD2 1 
ATOM   4217 C  CE1 . HIS B 1 31  ? 150.156 155.147 138.308 1.00 49.93  ? 31  HIS B CE1 1 
ATOM   4218 N  NE2 . HIS B 1 31  ? 150.149 156.079 137.373 1.00 49.93  ? 31  HIS B NE2 1 
ATOM   4219 N  N   . THR B 1 32  ? 146.102 151.299 134.613 1.00 43.39  ? 32  THR B N   1 
ATOM   4220 C  CA  . THR B 1 32  ? 145.587 150.126 133.904 1.00 43.39  ? 32  THR B CA  1 
ATOM   4221 C  C   . THR B 1 32  ? 146.530 148.927 134.046 1.00 43.39  ? 32  THR B C   1 
ATOM   4222 O  O   . THR B 1 32  ? 147.111 148.442 133.074 1.00 43.39  ? 32  THR B O   1 
ATOM   4223 C  CB  . THR B 1 32  ? 145.336 150.444 132.423 1.00 43.39  ? 32  THR B CB  1 
ATOM   4224 O  OG1 . THR B 1 32  ? 146.581 150.434 131.714 1.00 43.39  ? 32  THR B OG1 1 
ATOM   4225 C  CG2 . THR B 1 32  ? 144.682 151.807 132.256 1.00 43.39  ? 32  THR B CG2 1 
ATOM   4226 N  N   . LYS B 1 33  ? 146.676 148.449 135.282 1.00 38.72  ? 33  LYS B N   1 
ATOM   4227 C  CA  . LYS B 1 33  ? 147.578 147.339 135.567 1.00 38.72  ? 33  LYS B CA  1 
ATOM   4228 C  C   . LYS B 1 33  ? 146.839 146.060 135.946 1.00 38.72  ? 33  LYS B C   1 
ATOM   4229 O  O   . LYS B 1 33  ? 146.963 145.049 135.250 1.00 38.72  ? 33  LYS B O   1 
ATOM   4230 C  CB  . LYS B 1 33  ? 148.575 147.758 136.664 1.00 38.72  ? 33  LYS B CB  1 
ATOM   4231 C  CG  . LYS B 1 33  ? 147.947 148.298 137.947 1.00 38.72  ? 33  LYS B CG  1 
ATOM   4232 C  CD  . LYS B 1 33  ? 148.840 148.058 139.155 1.00 38.72  ? 33  LYS B CD  1 
ATOM   4233 C  CE  . LYS B 1 33  ? 148.196 148.575 140.434 1.00 38.72  ? 33  LYS B CE  1 
ATOM   4234 N  NZ  . LYS B 1 33  ? 147.065 147.717 140.884 1.00 38.72  ? 33  LYS B NZ  1 
ATOM   4235 N  N   . GLU B 1 34  ? 146.054 146.077 137.022 1.00 34.45  ? 34  GLU B N   1 
ATOM   4236 C  CA  . GLU B 1 34  ? 145.194 144.956 137.374 1.00 34.45  ? 34  GLU B CA  1 
ATOM   4237 C  C   . GLU B 1 34  ? 143.809 145.409 137.800 1.00 34.45  ? 34  GLU B C   1 
ATOM   4238 O  O   . GLU B 1 34  ? 142.972 144.561 138.122 1.00 34.45  ? 34  GLU B O   1 
ATOM   4239 C  CB  . GLU B 1 34  ? 145.812 144.103 138.498 1.00 34.45  ? 34  GLU B CB  1 
ATOM   4240 C  CG  . GLU B 1 34  ? 146.950 143.197 138.060 1.00 34.45  ? 34  GLU B CG  1 
ATOM   4241 C  CD  . GLU B 1 34  ? 148.310 143.832 138.240 1.00 34.45  ? 34  GLU B CD  1 
ATOM   4242 O  OE1 . GLU B 1 34  ? 148.380 144.938 138.812 1.00 34.45  ? 34  GLU B OE1 1 
ATOM   4243 O  OE2 . GLU B 1 34  ? 149.312 143.225 137.809 1.00 34.45  ? 34  GLU B OE2 1 
ATOM   4244 N  N   . ALA B 1 35  ? 143.547 146.716 137.824 1.00 27.47  ? 35  ALA B N   1 
ATOM   4245 C  CA  . ALA B 1 35  ? 142.237 147.232 138.179 1.00 27.47  ? 35  ALA B CA  1 
ATOM   4246 C  C   . ALA B 1 35  ? 141.200 146.999 137.093 1.00 27.47  ? 35  ALA B C   1 
ATOM   4247 O  O   . ALA B 1 35  ? 140.010 147.179 137.356 1.00 27.47  ? 35  ALA B O   1 
ATOM   4248 C  CB  . ALA B 1 35  ? 142.336 148.724 138.491 1.00 27.47  ? 35  ALA B CB  1 
ATOM   4249 N  N   . GLU B 1 36  ? 141.614 146.610 135.887 1.00 25.99  ? 36  GLU B N   1 
ATOM   4250 C  CA  . GLU B 1 36  ? 140.647 146.299 134.841 1.00 25.99  ? 36  GLU B CA  1 
ATOM   4251 C  C   . GLU B 1 36  ? 139.880 145.023 135.166 1.00 25.99  ? 36  GLU B C   1 
ATOM   4252 O  O   . GLU B 1 36  ? 138.644 144.993 135.105 1.00 25.99  ? 36  GLU B O   1 
ATOM   4253 C  CB  . GLU B 1 36  ? 141.361 146.179 133.496 1.00 25.99  ? 36  GLU B CB  1 
ATOM   4254 C  CG  . GLU B 1 36  ? 142.390 147.270 133.252 1.00 25.99  ? 36  GLU B CG  1 
ATOM   4255 C  CD  . GLU B 1 36  ? 142.931 147.257 131.837 1.00 25.99  ? 36  GLU B CD  1 
ATOM   4256 O  OE1 . GLU B 1 36  ? 143.209 146.158 131.316 1.00 25.99  ? 36  GLU B OE1 1 
ATOM   4257 O  OE2 . GLU B 1 36  ? 143.080 148.346 131.245 1.00 25.99  ? 36  GLU B OE2 1 
ATOM   4258 N  N   . CYS B 1 37  ? 140.596 143.959 135.534 1.00 23.44  ? 37  CYS B N   1 
ATOM   4259 C  CA  . CYS B 1 37  ? 139.924 142.724 135.926 1.00 23.44  ? 37  CYS B CA  1 
ATOM   4260 C  C   . CYS B 1 37  ? 139.164 142.901 137.233 1.00 23.44  ? 37  CYS B C   1 
ATOM   4261 O  O   . CYS B 1 37  ? 138.094 142.312 137.417 1.00 23.44  ? 37  CYS B O   1 
ATOM   4262 C  CB  . CYS B 1 37  ? 140.932 141.585 136.045 1.00 23.44  ? 37  CYS B CB  1 
ATOM   4263 S  SG  . CYS B 1 37  ? 140.187 139.952 135.897 1.00 23.44  ? 37  CYS B SG  1 
ATOM   4264 N  N   . ALA B 1 38  ? 139.701 143.702 138.155 1.00 22.29  ? 38  ALA B N   1 
ATOM   4265 C  CA  . ALA B 1 38  ? 138.979 143.991 139.388 1.00 22.29  ? 38  ALA B CA  1 
ATOM   4266 C  C   . ALA B 1 38  ? 137.681 144.734 139.101 1.00 22.29  ? 38  ALA B C   1 
ATOM   4267 O  O   . ALA B 1 38  ? 136.647 144.451 139.714 1.00 22.29  ? 38  ALA B O   1 
ATOM   4268 C  CB  . ALA B 1 38  ? 139.862 144.797 140.339 1.00 22.29  ? 38  ALA B CB  1 
ATOM   4269 N  N   . TYR B 1 39  ? 137.717 145.691 138.172 1.00 19.42  ? 39  TYR B N   1 
ATOM   4270 C  CA  . TYR B 1 39  ? 136.509 146.407 137.781 1.00 19.42  ? 39  TYR B CA  1 
ATOM   4271 C  C   . TYR B 1 39  ? 135.499 145.468 137.135 1.00 19.42  ? 39  TYR B C   1 
ATOM   4272 O  O   . TYR B 1 39  ? 134.298 145.540 137.424 1.00 19.42  ? 39  TYR B O   1 
ATOM   4273 C  CB  . TYR B 1 39  ? 136.878 147.550 136.833 1.00 19.42  ? 39  TYR B CB  1 
ATOM   4274 C  CG  . TYR B 1 39  ? 135.753 148.049 135.957 1.00 19.42  ? 39  TYR B CG  1 
ATOM   4275 C  CD1 . TYR B 1 39  ? 134.823 148.954 136.442 1.00 19.42  ? 39  TYR B CD1 1 
ATOM   4276 C  CD2 . TYR B 1 39  ? 135.633 147.632 134.640 1.00 19.42  ? 39  TYR B CD2 1 
ATOM   4277 C  CE1 . TYR B 1 39  ? 133.798 149.420 135.646 1.00 19.42  ? 39  TYR B CE1 1 
ATOM   4278 C  CE2 . TYR B 1 39  ? 134.610 148.091 133.837 1.00 19.42  ? 39  TYR B CE2 1 
ATOM   4279 C  CZ  . TYR B 1 39  ? 133.696 148.985 134.346 1.00 19.42  ? 39  TYR B CZ  1 
ATOM   4280 O  OH  . TYR B 1 39  ? 132.674 149.450 133.552 1.00 19.42  ? 39  TYR B OH  1 
ATOM   4281 N  N   . THR B 1 40  ? 135.971 144.579 136.258 1.00 16.91  ? 40  THR B N   1 
ATOM   4282 C  CA  . THR B 1 40  ? 135.077 143.607 135.634 1.00 16.91  ? 40  THR B CA  1 
ATOM   4283 C  C   . THR B 1 40  ? 134.418 142.723 136.684 1.00 16.91  ? 40  THR B C   1 
ATOM   4284 O  O   . THR B 1 40  ? 133.199 142.506 136.660 1.00 16.91  ? 40  THR B O   1 
ATOM   4285 C  CB  . THR B 1 40  ? 135.851 142.753 134.631 1.00 16.91  ? 40  THR B CB  1 
ATOM   4286 O  OG1 . THR B 1 40  ? 136.432 143.595 133.628 1.00 16.91  ? 40  THR B OG1 1 
ATOM   4287 C  CG2 . THR B 1 40  ? 134.930 141.743 133.970 1.00 16.91  ? 40  THR B CG2 1 
ATOM   4288 N  N   . LEU B 1 41  ? 135.215 142.212 137.624 1.00 17.85  ? 41  LEU B N   1 
ATOM   4289 C  CA  . LEU B 1 41  ? 134.682 141.355 138.674 1.00 17.85  ? 41  LEU B CA  1 
ATOM   4290 C  C   . LEU B 1 41  ? 133.687 142.106 139.548 1.00 17.85  ? 41  LEU B C   1 
ATOM   4291 O  O   . LEU B 1 41  ? 132.638 141.563 139.906 1.00 17.85  ? 41  LEU B O   1 
ATOM   4292 C  CB  . LEU B 1 41  ? 135.825 140.796 139.518 1.00 17.85  ? 41  LEU B CB  1 
ATOM   4293 C  CG  . LEU B 1 41  ? 135.438 140.144 140.844 1.00 17.85  ? 41  LEU B CG  1 
ATOM   4294 C  CD1 . LEU B 1 41  ? 134.592 138.911 140.600 1.00 17.85  ? 41  LEU B CD1 1 
ATOM   4295 C  CD2 . LEU B 1 41  ? 136.680 139.797 141.645 1.00 17.85  ? 41  LEU B CD2 1 
ATOM   4296 N  N   . PHE B 1 42  ? 133.997 143.355 139.901 1.00 19.43  ? 42  PHE B N   1 
ATOM   4297 C  CA  . PHE B 1 42  ? 133.090 144.133 140.737 1.00 19.43  ? 42  PHE B CA  1 
ATOM   4298 C  C   . PHE B 1 42  ? 131.766 144.382 140.033 1.00 19.43  ? 42  PHE B C   1 
ATOM   4299 O  O   . PHE B 1 42  ? 130.699 144.244 140.640 1.00 19.43  ? 42  PHE B O   1 
ATOM   4300 C  CB  . PHE B 1 42  ? 133.743 145.456 141.135 1.00 19.43  ? 42  PHE B CB  1 
ATOM   4301 C  CG  . PHE B 1 42  ? 134.751 145.326 142.239 1.00 19.43  ? 42  PHE B CG  1 
ATOM   4302 C  CD1 . PHE B 1 42  ? 134.778 144.197 143.040 1.00 19.43  ? 42  PHE B CD1 1 
ATOM   4303 C  CD2 . PHE B 1 42  ? 135.669 146.334 142.478 1.00 19.43  ? 42  PHE B CD2 1 
ATOM   4304 C  CE1 . PHE B 1 42  ? 135.704 144.074 144.057 1.00 19.43  ? 42  PHE B CE1 1 
ATOM   4305 C  CE2 . PHE B 1 42  ? 136.598 146.218 143.494 1.00 19.43  ? 42  PHE B CE2 1 
ATOM   4306 C  CZ  . PHE B 1 42  ? 136.615 145.086 144.284 1.00 19.43  ? 42  PHE B CZ  1 
ATOM   4307 N  N   . VAL B 1 43  ? 131.810 144.740 138.747 1.00 16.58  ? 43  VAL B N   1 
ATOM   4308 C  CA  . VAL B 1 43  ? 130.576 145.006 138.010 1.00 16.58  ? 43  VAL B CA  1 
ATOM   4309 C  C   . VAL B 1 43  ? 129.741 143.736 137.892 1.00 16.58  ? 43  VAL B C   1 
ATOM   4310 O  O   . VAL B 1 43  ? 128.523 143.746 138.123 1.00 16.58  ? 43  VAL B O   1 
ATOM   4311 C  CB  . VAL B 1 43  ? 130.894 145.605 136.629 1.00 16.58  ? 43  VAL B CB  1 
ATOM   4312 C  CG1 . VAL B 1 43  ? 129.655 145.618 135.758 1.00 16.58  ? 43  VAL B CG1 1 
ATOM   4313 C  CG2 . VAL B 1 43  ? 131.443 147.008 136.785 1.00 16.58  ? 43  VAL B CG2 1 
ATOM   4314 N  N   . VAL B 1 44  ? 130.384 142.619 137.543 1.00 14.51  ? 44  VAL B N   1 
ATOM   4315 C  CA  . VAL B 1 44  ? 129.649 141.367 137.383 1.00 14.51  ? 44  VAL B CA  1 
ATOM   4316 C  C   . VAL B 1 44  ? 129.050 140.922 138.712 1.00 14.51  ? 44  VAL B C   1 
ATOM   4317 O  O   . VAL B 1 44  ? 127.894 140.490 138.774 1.00 14.51  ? 44  VAL B O   1 
ATOM   4318 C  CB  . VAL B 1 44  ? 130.560 140.287 136.773 1.00 14.51  ? 44  VAL B CB  1 
ATOM   4319 C  CG1 . VAL B 1 44  ? 129.886 138.935 136.824 1.00 14.51  ? 44  VAL B CG1 1 
ATOM   4320 C  CG2 . VAL B 1 44  ? 130.910 140.645 135.342 1.00 14.51  ? 44  VAL B CG2 1 
ATOM   4321 N  N   . ALA B 1 45  ? 129.819 141.032 139.799 1.00 15.66  ? 45  ALA B N   1 
ATOM   4322 C  CA  . ALA B 1 45  ? 129.311 140.644 141.111 1.00 15.66  ? 45  ALA B CA  1 
ATOM   4323 C  C   . ALA B 1 45  ? 128.159 141.538 141.549 1.00 15.66  ? 45  ALA B C   1 
ATOM   4324 O  O   . ALA B 1 45  ? 127.183 141.058 142.136 1.00 15.66  ? 45  ALA B O   1 
ATOM   4325 C  CB  . ALA B 1 45  ? 130.439 140.680 142.140 1.00 15.66  ? 45  ALA B CB  1 
ATOM   4326 N  N   . THR B 1 46  ? 128.256 142.843 141.285 1.00 16.70  ? 46  THR B N   1 
ATOM   4327 C  CA  . THR B 1 46  ? 127.164 143.746 141.626 1.00 16.70  ? 46  THR B CA  1 
ATOM   4328 C  C   . THR B 1 46  ? 125.901 143.390 140.857 1.00 16.70  ? 46  THR B C   1 
ATOM   4329 O  O   . THR B 1 46  ? 124.798 143.410 141.414 1.00 16.70  ? 46  THR B O   1 
ATOM   4330 C  CB  . THR B 1 46  ? 127.567 145.193 141.346 1.00 16.70  ? 46  THR B CB  1 
ATOM   4331 O  OG1 . THR B 1 46  ? 128.794 145.489 142.023 1.00 16.70  ? 46  THR B OG1 1 
ATOM   4332 C  CG2 . THR B 1 46  ? 126.490 146.146 141.829 1.00 16.70  ? 46  THR B CG2 1 
ATOM   4333 N  N   . PHE B 1 47  ? 126.042 143.057 139.572 1.00 16.16  ? 47  PHE B N   1 
ATOM   4334 C  CA  . PHE B 1 47  ? 124.874 142.661 138.794 1.00 16.16  ? 47  PHE B CA  1 
ATOM   4335 C  C   . PHE B 1 47  ? 124.338 141.304 139.230 1.00 16.16  ? 47  PHE B C   1 
ATOM   4336 O  O   . PHE B 1 47  ? 123.161 141.005 139.009 1.00 16.16  ? 47  PHE B O   1 
ATOM   4337 C  CB  . PHE B 1 47  ? 125.215 142.641 137.307 1.00 16.16  ? 47  PHE B CB  1 
ATOM   4338 C  CG  . PHE B 1 47  ? 125.286 144.000 136.688 1.00 16.16  ? 47  PHE B CG  1 
ATOM   4339 C  CD1 . PHE B 1 47  ? 124.600 145.060 137.244 1.00 16.16  ? 47  PHE B CD1 1 
ATOM   4340 C  CD2 . PHE B 1 47  ? 126.037 144.217 135.550 1.00 16.16  ? 47  PHE B CD2 1 
ATOM   4341 C  CE1 . PHE B 1 47  ? 124.662 146.307 136.677 1.00 16.16  ? 47  PHE B CE1 1 
ATOM   4342 C  CE2 . PHE B 1 47  ? 126.104 145.467 134.979 1.00 16.16  ? 47  PHE B CE2 1 
ATOM   4343 C  CZ  . PHE B 1 47  ? 125.416 146.513 135.544 1.00 16.16  ? 47  PHE B CZ  1 
ATOM   4344 N  N   . TRP B 1 48  ? 125.187 140.459 139.815 1.00 14.86  ? 48  TRP B N   1 
ATOM   4345 C  CA  . TRP B 1 48  ? 124.718 139.166 140.302 1.00 14.86  ? 48  TRP B CA  1 
ATOM   4346 C  C   . TRP B 1 48  ? 123.972 139.294 141.625 1.00 14.86  ? 48  TRP B C   1 
ATOM   4347 O  O   . TRP B 1 48  ? 122.965 138.610 141.838 1.00 14.86  ? 48  TRP B O   1 
ATOM   4348 C  CB  . TRP B 1 48  ? 125.894 138.201 140.443 1.00 14.86  ? 48  TRP B CB  1 
ATOM   4349 C  CG  . TRP B 1 48  ? 126.225 137.486 139.174 1.00 14.86  ? 48  TRP B CG  1 
ATOM   4350 C  CD1 . TRP B 1 48  ? 125.406 137.306 138.101 1.00 14.86  ? 48  TRP B CD1 1 
ATOM   4351 C  CD2 . TRP B 1 48  ? 127.468 136.860 138.840 1.00 14.86  ? 48  TRP B CD2 1 
ATOM   4352 N  NE1 . TRP B 1 48  ? 126.059 136.604 137.120 1.00 14.86  ? 48  TRP B NE1 1 
ATOM   4353 C  CE2 . TRP B 1 48  ? 127.328 136.320 137.549 1.00 14.86  ? 48  TRP B CE2 1 
ATOM   4354 C  CE3 . TRP B 1 48  ? 128.685 136.704 139.508 1.00 14.86  ? 48  TRP B CE3 1 
ATOM   4355 C  CZ2 . TRP B 1 48  ? 128.357 135.634 136.912 1.00 14.86  ? 48  TRP B CZ2 1 
ATOM   4356 C  CZ3 . TRP B 1 48  ? 129.705 136.023 138.874 1.00 14.86  ? 48  TRP B CZ3 1 
ATOM   4357 C  CH2 . TRP B 1 48  ? 129.535 135.497 137.590 1.00 14.86  ? 48  TRP B CH2 1 
ATOM   4358 N  N   . LEU B 1 49  ? 124.450 140.156 142.526 1.00 20.30  ? 49  LEU B N   1 
ATOM   4359 C  CA  . LEU B 1 49  ? 123.800 140.309 143.826 1.00 20.30  ? 49  LEU B CA  1 
ATOM   4360 C  C   . LEU B 1 49  ? 122.397 140.882 143.679 1.00 20.30  ? 49  LEU B C   1 
ATOM   4361 O  O   . LEU B 1 49  ? 121.432 140.337 144.228 1.00 20.30  ? 49  LEU B O   1 
ATOM   4362 C  CB  . LEU B 1 49  ? 124.645 141.195 144.741 1.00 20.30  ? 49  LEU B CB  1 
ATOM   4363 C  CG  . LEU B 1 49  ? 125.642 140.515 145.680 1.00 20.30  ? 49  LEU B CG  1 
ATOM   4364 C  CD1 . LEU B 1 49  ? 124.903 139.666 146.699 1.00 20.30  ? 49  LEU B CD1 1 
ATOM   4365 C  CD2 . LEU B 1 49  ? 126.649 139.677 144.918 1.00 20.30  ? 49  LEU B CD2 1 
ATOM   4366 N  N   . THR B 1 50  ? 122.262 141.980 142.946 1.00 24.80  ? 50  THR B N   1 
ATOM   4367 C  CA  . THR B 1 50  ? 120.973 142.611 142.707 1.00 24.80  ? 50  THR B CA  1 
ATOM   4368 C  C   . THR B 1 50  ? 120.555 142.393 141.259 1.00 24.80  ? 50  THR B C   1 
ATOM   4369 O  O   . THR B 1 50  ? 121.371 142.506 140.340 1.00 24.80  ? 50  THR B O   1 
ATOM   4370 C  CB  . THR B 1 50  ? 121.020 144.107 143.047 1.00 24.80  ? 50  THR B CB  1 
ATOM   4371 O  OG1 . THR B 1 50  ? 119.705 144.668 142.939 1.00 24.80  ? 50  THR B OG1 1 
ATOM   4372 C  CG2 . THR B 1 50  ? 121.982 144.855 142.145 1.00 24.80  ? 50  THR B CG2 1 
ATOM   4373 N  N   . GLU B 1 51  ? 119.279 142.063 141.060 1.00 29.39  ? 51  GLU B N   1 
ATOM   4374 C  CA  . GLU B 1 51  ? 118.788 141.628 139.752 1.00 29.39  ? 51  GLU B CA  1 
ATOM   4375 C  C   . GLU B 1 51  ? 118.635 142.834 138.823 1.00 29.39  ? 51  GLU B C   1 
ATOM   4376 O  O   . GLU B 1 51  ? 117.544 143.195 138.379 1.00 29.39  ? 51  GLU B O   1 
ATOM   4377 C  CB  . GLU B 1 51  ? 117.475 140.872 139.902 1.00 29.39  ? 51  GLU B CB  1 
ATOM   4378 C  CG  . GLU B 1 51  ? 117.525 139.616 140.780 1.00 29.39  ? 51  GLU B CG  1 
ATOM   4379 C  CD  . GLU B 1 51  ? 118.384 138.485 140.226 1.00 29.39  ? 51  GLU B CD  1 
ATOM   4380 O  OE1 . GLU B 1 51  ? 118.158 137.332 140.646 1.00 29.39  ? 51  GLU B OE1 1 
ATOM   4381 O  OE2 . GLU B 1 51  ? 119.275 138.723 139.385 1.00 29.39  ? 51  GLU B OE2 1 
ATOM   4382 N  N   . ALA B 1 52  ? 119.773 143.462 138.527 1.00 24.81  ? 52  ALA B N   1 
ATOM   4383 C  CA  . ALA B 1 52  ? 119.781 144.552 137.559 1.00 24.81  ? 52  ALA B CA  1 
ATOM   4384 C  C   . ALA B 1 52  ? 119.647 144.025 136.137 1.00 24.81  ? 52  ALA B C   1 
ATOM   4385 O  O   . ALA B 1 52  ? 118.989 144.650 135.297 1.00 24.81  ? 52  ALA B O   1 
ATOM   4386 C  CB  . ALA B 1 52  ? 121.057 145.377 137.711 1.00 24.81  ? 52  ALA B CB  1 
ATOM   4387 N  N   . LEU B 1 53  ? 120.262 142.887 135.855 1.00 17.96  ? 53  LEU B N   1 
ATOM   4388 C  CA  . LEU B 1 53  ? 120.169 142.197 134.579 1.00 17.96  ? 53  LEU B CA  1 
ATOM   4389 C  C   . LEU B 1 53  ? 119.958 140.719 134.858 1.00 17.96  ? 53  LEU B C   1 
ATOM   4390 O  O   . LEU B 1 53  ? 120.244 140.245 135.963 1.00 17.96  ? 53  LEU B O   1 
ATOM   4391 C  CB  . LEU B 1 53  ? 121.432 142.398 133.729 1.00 17.96  ? 53  LEU B CB  1 
ATOM   4392 C  CG  . LEU B 1 53  ? 121.745 143.817 133.260 1.00 17.96  ? 53  LEU B CG  1 
ATOM   4393 C  CD1 . LEU B 1 53  ? 123.077 143.855 132.536 1.00 17.96  ? 53  LEU B CD1 1 
ATOM   4394 C  CD2 . LEU B 1 53  ? 120.635 144.324 132.363 1.00 17.96  ? 53  LEU B CD2 1 
ATOM   4395 N  N   . PRO B 1 54  ? 119.446 139.967 133.884 1.00 14.55  ? 54  PRO B N   1 
ATOM   4396 C  CA  . PRO B 1 54  ? 119.355 138.514 134.060 1.00 14.55  ? 54  PRO B CA  1 
ATOM   4397 C  C   . PRO B 1 54  ? 120.729 137.914 134.310 1.00 14.55  ? 54  PRO B C   1 
ATOM   4398 O  O   . PRO B 1 54  ? 121.747 138.417 133.831 1.00 14.55  ? 54  PRO B O   1 
ATOM   4399 C  CB  . PRO B 1 54  ? 118.761 138.031 132.734 1.00 14.55  ? 54  PRO B CB  1 
ATOM   4400 C  CG  . PRO B 1 54  ? 118.014 139.204 132.214 1.00 14.55  ? 54  PRO B CG  1 
ATOM   4401 C  CD  . PRO B 1 54  ? 118.795 140.411 132.640 1.00 14.55  ? 54  PRO B CD  1 
ATOM   4402 N  N   . LEU B 1 55  ? 120.748 136.831 135.089 1.00 14.28  ? 55  LEU B N   1 
ATOM   4403 C  CA  . LEU B 1 55  ? 122.015 136.260 135.536 1.00 14.28  ? 55  LEU B CA  1 
ATOM   4404 C  C   . LEU B 1 55  ? 122.871 135.809 134.360 1.00 14.28  ? 55  LEU B C   1 
ATOM   4405 O  O   . LEU B 1 55  ? 124.093 135.995 134.367 1.00 14.28  ? 55  LEU B O   1 
ATOM   4406 C  CB  . LEU B 1 55  ? 121.756 135.098 136.494 1.00 14.28  ? 55  LEU B CB  1 
ATOM   4407 C  CG  . LEU B 1 55  ? 121.425 135.473 137.940 1.00 14.28  ? 55  LEU B CG  1 
ATOM   4408 C  CD1 . LEU B 1 55  ? 119.950 135.795 138.092 1.00 14.28  ? 55  LEU B CD1 1 
ATOM   4409 C  CD2 . LEU B 1 55  ? 121.829 134.363 138.890 1.00 14.28  ? 55  LEU B CD2 1 
ATOM   4410 N  N   . SER B 1 56  ? 122.254 135.207 133.343 1.00 11.95  ? 56  SER B N   1 
ATOM   4411 C  CA  . SER B 1 56  ? 123.012 134.783 132.171 1.00 11.95  ? 56  SER B CA  1 
ATOM   4412 C  C   . SER B 1 56  ? 123.534 135.972 131.372 1.00 11.95  ? 56  SER B C   1 
ATOM   4413 O  O   . SER B 1 56  ? 124.648 135.919 130.834 1.00 11.95  ? 56  SER B O   1 
ATOM   4414 C  CB  . SER B 1 56  ? 122.145 133.884 131.297 1.00 11.95  ? 56  SER B CB  1 
ATOM   4415 O  OG  . SER B 1 56  ? 121.677 132.773 132.039 1.00 11.95  ? 56  SER B OG  1 
ATOM   4416 N  N   . VAL B 1 57  ? 122.753 137.051 131.284 1.00 11.27  ? 57  VAL B N   1 
ATOM   4417 C  CA  . VAL B 1 57  ? 123.226 138.251 130.601 1.00 11.27  ? 57  VAL B CA  1 
ATOM   4418 C  C   . VAL B 1 57  ? 124.450 138.814 131.310 1.00 11.27  ? 57  VAL B C   1 
ATOM   4419 O  O   . VAL B 1 57  ? 125.424 139.225 130.669 1.00 11.27  ? 57  VAL B O   1 
ATOM   4420 C  CB  . VAL B 1 57  ? 122.097 139.291 130.505 1.00 11.27  ? 57  VAL B CB  1 
ATOM   4421 C  CG1 . VAL B 1 57  ? 122.582 140.532 129.784 1.00 11.27  ? 57  VAL B CG1 1 
ATOM   4422 C  CG2 . VAL B 1 57  ? 120.900 138.694 129.798 1.00 11.27  ? 57  VAL B CG2 1 
ATOM   4423 N  N   . THR B 1 58  ? 124.420 138.840 132.643 1.00 11.54  ? 58  THR B N   1 
ATOM   4424 C  CA  . THR B 1 58  ? 125.597 139.248 133.400 1.00 11.54  ? 58  THR B CA  1 
ATOM   4425 C  C   . THR B 1 58  ? 126.766 138.301 133.168 1.00 11.54  ? 58  THR B C   1 
ATOM   4426 O  O   . THR B 1 58  ? 127.911 138.748 133.050 1.00 11.54  ? 58  THR B O   1 
ATOM   4427 C  CB  . THR B 1 58  ? 125.265 139.318 134.888 1.00 11.54  ? 58  THR B CB  1 
ATOM   4428 O  OG1 . THR B 1 58  ? 124.184 140.234 135.096 1.00 11.54  ? 58  THR B OG1 1 
ATOM   4429 C  CG2 . THR B 1 58  ? 126.474 139.778 135.677 1.00 11.54  ? 58  THR B CG2 1 
ATOM   4430 N  N   . ALA B 1 59  ? 126.502 136.995 133.105 1.00 10.27  ? 59  ALA B N   1 
ATOM   4431 C  CA  . ALA B 1 59  ? 127.567 136.036 132.846 1.00 10.27  ? 59  ALA B CA  1 
ATOM   4432 C  C   . ALA B 1 59  ? 128.186 136.221 131.468 1.00 10.27  ? 59  ALA B C   1 
ATOM   4433 O  O   . ALA B 1 59  ? 129.336 135.825 131.258 1.00 10.27  ? 59  ALA B O   1 
ATOM   4434 C  CB  . ALA B 1 59  ? 127.036 134.613 132.990 1.00 10.27  ? 59  ALA B CB  1 
ATOM   4435 N  N   . LEU B 1 60  ? 127.443 136.788 130.523 1.00 10.43  ? 60  LEU B N   1 
ATOM   4436 C  CA  . LEU B 1 60  ? 128.000 137.105 129.213 1.00 10.43  ? 60  LEU B CA  1 
ATOM   4437 C  C   . LEU B 1 60  ? 128.871 138.356 129.216 1.00 10.43  ? 60  LEU B C   1 
ATOM   4438 O  O   . LEU B 1 60  ? 129.576 138.599 128.231 1.00 10.43  ? 60  LEU B O   1 
ATOM   4439 C  CB  . LEU B 1 60  ? 126.882 137.272 128.180 1.00 10.43  ? 60  LEU B CB  1 
ATOM   4440 C  CG  . LEU B 1 60  ? 126.098 136.008 127.831 1.00 10.43  ? 60  LEU B CG  1 
ATOM   4441 C  CD1 . LEU B 1 60  ? 124.716 136.359 127.309 1.00 10.43  ? 60  LEU B CD1 1 
ATOM   4442 C  CD2 . LEU B 1 60  ? 126.863 135.171 126.823 1.00 10.43  ? 60  LEU B CD2 1 
ATOM   4443 N  N   . LEU B 1 61  ? 128.836 139.151 130.284 1.00 11.16  ? 61  LEU B N   1 
ATOM   4444 C  CA  . LEU B 1 61  ? 129.648 140.365 130.338 1.00 11.16  ? 61  LEU B CA  1 
ATOM   4445 C  C   . LEU B 1 61  ? 131.151 140.115 130.257 1.00 11.16  ? 61  LEU B C   1 
ATOM   4446 O  O   . LEU B 1 61  ? 131.836 140.910 129.590 1.00 11.16  ? 61  LEU B O   1 
ATOM   4447 C  CB  . LEU B 1 61  ? 129.304 141.165 131.601 1.00 11.16  ? 61  LEU B CB  1 
ATOM   4448 C  CG  . LEU B 1 61  ? 128.028 142.004 131.545 1.00 11.16  ? 61  LEU B CG  1 
ATOM   4449 C  CD1 . LEU B 1 61  ? 127.889 142.843 132.799 1.00 11.16  ? 61  LEU B CD1 1 
ATOM   4450 C  CD2 . LEU B 1 61  ? 128.021 142.880 130.310 1.00 11.16  ? 61  LEU B CD2 1 
ATOM   4451 N  N   . PRO B 1 62  ? 131.732 139.100 130.916 1.00 11.70  ? 62  PRO B N   1 
ATOM   4452 C  CA  . PRO B 1 62  ? 133.180 138.880 130.754 1.00 11.70  ? 62  PRO B CA  1 
ATOM   4453 C  C   . PRO B 1 62  ? 133.612 138.732 129.307 1.00 11.70  ? 62  PRO B C   1 
ATOM   4454 O  O   . PRO B 1 62  ? 134.675 139.244 128.934 1.00 11.70  ? 62  PRO B O   1 
ATOM   4455 C  CB  . PRO B 1 62  ? 133.426 137.595 131.551 1.00 11.70  ? 62  PRO B CB  1 
ATOM   4456 C  CG  . PRO B 1 62  ? 132.394 137.606 132.590 1.00 11.70  ? 62  PRO B CG  1 
ATOM   4457 C  CD  . PRO B 1 62  ? 131.183 138.268 132.003 1.00 11.70  ? 62  PRO B CD  1 
ATOM   4458 N  N   . SER B 1 63  ? 132.799 138.076 128.475 1.00 13.59  ? 63  SER B N   1 
ATOM   4459 C  CA  . SER B 1 63  ? 133.112 137.945 127.057 1.00 13.59  ? 63  SER B CA  1 
ATOM   4460 C  C   . SER B 1 63  ? 133.235 139.293 126.366 1.00 13.59  ? 63  SER B C   1 
ATOM   4461 O  O   . SER B 1 63  ? 133.846 139.377 125.297 1.00 13.59  ? 63  SER B O   1 
ATOM   4462 C  CB  . SER B 1 63  ? 132.043 137.106 126.361 1.00 13.59  ? 63  SER B CB  1 
ATOM   4463 O  OG  . SER B 1 63  ? 131.988 135.803 126.905 1.00 13.59  ? 63  SER B OG  1 
ATOM   4464 N  N   . LEU B 1 64  ? 132.653 140.341 126.941 1.00 13.90  ? 64  LEU B N   1 
ATOM   4465 C  CA  . LEU B 1 64  ? 132.840 141.699 126.455 1.00 13.90  ? 64  LEU B CA  1 
ATOM   4466 C  C   . LEU B 1 64  ? 134.046 142.363 127.103 1.00 13.90  ? 64  LEU B C   1 
ATOM   4467 O  O   . LEU B 1 64  ? 134.932 142.866 126.407 1.00 13.90  ? 64  LEU B O   1 
ATOM   4468 C  CB  . LEU B 1 64  ? 131.586 142.530 126.729 1.00 13.90  ? 64  LEU B CB  1 
ATOM   4469 C  CG  . LEU B 1 64  ? 130.547 142.617 125.623 1.00 13.90  ? 64  LEU B CG  1 
ATOM   4470 C  CD1 . LEU B 1 64  ? 129.342 143.387 126.117 1.00 13.90  ? 64  LEU B CD1 1 
ATOM   4471 C  CD2 . LEU B 1 64  ? 131.159 143.295 124.424 1.00 13.90  ? 64  LEU B CD2 1 
ATOM   4472 N  N   . MET B 1 65  ? 134.101 142.347 128.434 1.00 14.94  ? 65  MET B N   1 
ATOM   4473 C  CA  . MET B 1 65  ? 135.069 143.175 129.144 1.00 14.94  ? 65  MET B CA  1 
ATOM   4474 C  C   . MET B 1 65  ? 136.492 142.649 128.991 1.00 14.94  ? 65  MET B C   1 
ATOM   4475 O  O   . MET B 1 65  ? 137.419 143.431 128.751 1.00 14.94  ? 65  MET B O   1 
ATOM   4476 C  CB  . MET B 1 65  ? 134.684 143.276 130.617 1.00 14.94  ? 65  MET B CB  1 
ATOM   4477 C  CG  . MET B 1 65  ? 133.225 143.635 130.843 1.00 14.94  ? 65  MET B CG  1 
ATOM   4478 S  SD  . MET B 1 65  ? 132.978 144.689 132.280 1.00 14.94  ? 65  MET B SD  1 
ATOM   4479 C  CE  . MET B 1 65  ? 131.212 144.954 132.194 1.00 14.94  ? 65  MET B CE  1 
ATOM   4480 N  N   . LEU B 1 66  ? 136.696 141.338 129.136 1.00 15.23  ? 66  LEU B N   1 
ATOM   4481 C  CA  . LEU B 1 66  ? 138.056 140.804 129.087 1.00 15.23  ? 66  LEU B CA  1 
ATOM   4482 C  C   . LEU B 1 66  ? 138.749 141.039 127.750 1.00 15.23  ? 66  LEU B C   1 
ATOM   4483 O  O   . LEU B 1 66  ? 139.921 141.453 127.757 1.00 15.23  ? 66  LEU B O   1 
ATOM   4484 C  CB  . LEU B 1 66  ? 138.043 139.318 129.463 1.00 15.23  ? 66  LEU B CB  1 
ATOM   4485 C  CG  . LEU B 1 66  ? 137.449 138.975 130.830 1.00 15.23  ? 66  LEU B CG  1 
ATOM   4486 C  CD1 . LEU B 1 66  ? 137.482 137.478 131.066 1.00 15.23  ? 66  LEU B CD1 1 
ATOM   4487 C  CD2 . LEU B 1 66  ? 138.186 139.703 131.935 1.00 15.23  ? 66  LEU B CD2 1 
ATOM   4488 N  N   . PRO B 1 67  ? 138.128 140.792 126.588 1.00 16.60  ? 67  PRO B N   1 
ATOM   4489 C  CA  . PRO B 1 67  ? 138.841 141.083 125.330 1.00 16.60  ? 67  PRO B CA  1 
ATOM   4490 C  C   . PRO B 1 67  ? 139.147 142.556 125.119 1.00 16.60  ? 67  PRO B C   1 
ATOM   4491 O  O   . PRO B 1 67  ? 140.252 142.885 124.672 1.00 16.60  ? 67  PRO B O   1 
ATOM   4492 C  CB  . PRO B 1 67  ? 137.896 140.543 124.248 1.00 16.60  ? 67  PRO B CB  1 
ATOM   4493 C  CG  . PRO B 1 67  ? 136.969 139.641 124.933 1.00 16.60  ? 67  PRO B CG  1 
ATOM   4494 C  CD  . PRO B 1 67  ? 136.860 140.082 126.347 1.00 16.60  ? 67  PRO B CD  1 
ATOM   4495 N  N   . MET B 1 68  ? 138.206 143.458 125.414 1.00 18.53  ? 68  MET B N   1 
ATOM   4496 C  CA  . MET B 1 68  ? 138.471 144.875 125.184 1.00 18.53  ? 68  MET B CA  1 
ATOM   4497 C  C   . MET B 1 68  ? 139.570 145.390 126.104 1.00 18.53  ? 68  MET B C   1 
ATOM   4498 O  O   . MET B 1 68  ? 140.410 146.195 125.686 1.00 18.53  ? 68  MET B O   1 
ATOM   4499 C  CB  . MET B 1 68  ? 137.201 145.708 125.356 1.00 18.53  ? 68  MET B CB  1 
ATOM   4500 C  CG  . MET B 1 68  ? 136.128 145.445 124.316 1.00 18.53  ? 68  MET B CG  1 
ATOM   4501 S  SD  . MET B 1 68  ? 134.687 146.509 124.525 1.00 18.53  ? 68  MET B SD  1 
ATOM   4502 C  CE  . MET B 1 68  ? 133.907 145.788 125.962 1.00 18.53  ? 68  MET B CE  1 
ATOM   4503 N  N   . PHE B 1 69  ? 139.581 144.941 127.359 1.00 18.33  ? 69  PHE B N   1 
ATOM   4504 C  CA  . PHE B 1 69  ? 140.637 145.330 128.284 1.00 18.33  ? 69  PHE B CA  1 
ATOM   4505 C  C   . PHE B 1 69  ? 141.990 144.744 127.911 1.00 18.33  ? 69  PHE B C   1 
ATOM   4506 O  O   . PHE B 1 69  ? 143.004 145.179 128.464 1.00 18.33  ? 69  PHE B O   1 
ATOM   4507 C  CB  . PHE B 1 69  ? 140.271 144.905 129.705 1.00 18.33  ? 69  PHE B CB  1 
ATOM   4508 C  CG  . PHE B 1 69  ? 139.378 145.875 130.417 1.00 18.33  ? 69  PHE B CG  1 
ATOM   4509 C  CD1 . PHE B 1 69  ? 139.692 147.220 130.459 1.00 18.33  ? 69  PHE B CD1 1 
ATOM   4510 C  CD2 . PHE B 1 69  ? 138.226 145.442 131.047 1.00 18.33  ? 69  PHE B CD2 1 
ATOM   4511 C  CE1 . PHE B 1 69  ? 138.874 148.115 131.114 1.00 18.33  ? 69  PHE B CE1 1 
ATOM   4512 C  CE2 . PHE B 1 69  ? 137.404 146.332 131.703 1.00 18.33  ? 69  PHE B CE2 1 
ATOM   4513 C  CZ  . PHE B 1 69  ? 137.729 147.670 131.737 1.00 18.33  ? 69  PHE B CZ  1 
ATOM   4514 N  N   . GLY B 1 70  ? 142.031 143.779 126.997 1.00 21.34  ? 70  GLY B N   1 
ATOM   4515 C  CA  . GLY B 1 70  ? 143.274 143.137 126.631 1.00 21.34  ? 70  GLY B CA  1 
ATOM   4516 C  C   . GLY B 1 70  ? 143.760 142.094 127.608 1.00 21.34  ? 70  GLY B C   1 
ATOM   4517 O  O   . GLY B 1 70  ? 144.899 141.633 127.482 1.00 21.34  ? 70  GLY B O   1 
ATOM   4518 N  N   . ILE B 1 71  ? 142.935 141.712 128.583 1.00 20.09  ? 71  ILE B N   1 
ATOM   4519 C  CA  . ILE B 1 71  ? 143.354 140.729 129.576 1.00 20.09  ? 71  ILE B CA  1 
ATOM   4520 C  C   . ILE B 1 71  ? 143.587 139.374 128.922 1.00 20.09  ? 71  ILE B C   1 
ATOM   4521 O  O   . ILE B 1 71  ? 144.595 138.707 129.181 1.00 20.09  ? 71  ILE B O   1 
ATOM   4522 C  CB  . ILE B 1 71  ? 142.315 140.640 130.708 1.00 20.09  ? 71  ILE B CB  1 
ATOM   4523 C  CG1 . ILE B 1 71  ? 142.249 141.963 131.468 1.00 20.09  ? 71  ILE B CG1 1 
ATOM   4524 C  CG2 . ILE B 1 71  ? 142.647 139.502 131.651 1.00 20.09  ? 71  ILE B CG2 1 
ATOM   4525 C  CD1 . ILE B 1 71  ? 141.017 142.110 132.317 1.00 20.09  ? 71  ILE B CD1 1 
ATOM   4526 N  N   . MET B 1 72  ? 142.668 138.951 128.057 1.00 22.81  ? 72  MET B N   1 
ATOM   4527 C  CA  . MET B 1 72  ? 142.760 137.641 127.429 1.00 22.81  ? 72  MET B CA  1 
ATOM   4528 C  C   . MET B 1 72  ? 141.925 137.650 126.159 1.00 22.81  ? 72  MET B C   1 
ATOM   4529 O  O   . MET B 1 72  ? 140.895 138.330 126.105 1.00 22.81  ? 72  MET B O   1 
ATOM   4530 C  CB  . MET B 1 72  ? 142.300 136.542 128.400 1.00 22.81  ? 72  MET B CB  1 
ATOM   4531 C  CG  . MET B 1 72  ? 140.816 136.518 128.675 1.00 22.81  ? 72  MET B CG  1 
ATOM   4532 S  SD  . MET B 1 72  ? 140.308 135.137 129.715 1.00 22.81  ? 72  MET B SD  1 
ATOM   4533 C  CE  . MET B 1 72  ? 141.273 133.804 129.022 1.00 22.81  ? 72  MET B CE  1 
ATOM   4534 N  N   . PRO B 1 73  ? 142.346 136.929 125.121 1.00 20.79  ? 73  PRO B N   1 
ATOM   4535 C  CA  . PRO B 1 73  ? 141.673 137.031 123.822 1.00 20.79  ? 73  PRO B CA  1 
ATOM   4536 C  C   . PRO B 1 73  ? 140.257 136.481 123.861 1.00 20.79  ? 73  PRO B C   1 
ATOM   4537 O  O   . PRO B 1 73  ? 139.897 135.657 124.703 1.00 20.79  ? 73  PRO B O   1 
ATOM   4538 C  CB  . PRO B 1 73  ? 142.560 136.194 122.893 1.00 20.79  ? 73  PRO B CB  1 
ATOM   4539 C  CG  . PRO B 1 73  ? 143.868 136.079 123.603 1.00 20.79  ? 73  PRO B CG  1 
ATOM   4540 C  CD  . PRO B 1 73  ? 143.535 136.066 125.056 1.00 20.79  ? 73  PRO B CD  1 
ATOM   4541 N  N   . SER B 1 74  ? 139.446 136.957 122.912 1.00 18.71  ? 74  SER B N   1 
ATOM   4542 C  CA  . SER B 1 74  ? 138.048 136.545 122.845 1.00 18.71  ? 74  SER B CA  1 
ATOM   4543 C  C   . SER B 1 74  ? 137.908 135.051 122.590 1.00 18.71  ? 74  SER B C   1 
ATOM   4544 O  O   . SER B 1 74  ? 136.959 134.424 123.077 1.00 18.71  ? 74  SER B O   1 
ATOM   4545 C  CB  . SER B 1 74  ? 137.323 137.336 121.758 1.00 18.71  ? 74  SER B CB  1 
ATOM   4546 O  OG  . SER B 1 74  ? 135.933 137.072 121.780 1.00 18.71  ? 74  SER B OG  1 
ATOM   4547 N  N   . LYS B 1 75  ? 138.836 134.463 121.831 1.00 19.62  ? 75  LYS B N   1 
ATOM   4548 C  CA  . LYS B 1 75  ? 138.786 133.026 121.584 1.00 19.62  ? 75  LYS B CA  1 
ATOM   4549 C  C   . LYS B 1 75  ? 138.936 132.239 122.879 1.00 19.62  ? 75  LYS B C   1 
ATOM   4550 O  O   . LYS B 1 75  ? 138.218 131.258 123.105 1.00 19.62  ? 75  LYS B O   1 
ATOM   4551 C  CB  . LYS B 1 75  ? 139.873 132.628 120.588 1.00 19.62  ? 75  LYS B CB  1 
ATOM   4552 C  CG  . LYS B 1 75  ? 139.711 133.249 119.214 1.00 19.62  ? 75  LYS B CG  1 
ATOM   4553 C  CD  . LYS B 1 75  ? 141.027 133.257 118.458 1.00 19.62  ? 75  LYS B CD  1 
ATOM   4554 C  CE  . LYS B 1 75  ? 141.432 131.851 118.047 1.00 19.62  ? 75  LYS B CE  1 
ATOM   4555 N  NZ  . LYS B 1 75  ? 142.911 131.681 118.031 1.00 19.62  ? 75  LYS B NZ  1 
ATOM   4556 N  N   . LYS B 1 76  ? 139.860 132.657 123.747 1.00 16.74  ? 76  LYS B N   1 
ATOM   4557 C  CA  . LYS B 1 76  ? 140.043 131.966 125.019 1.00 16.74  ? 76  LYS B CA  1 
ATOM   4558 C  C   . LYS B 1 76  ? 138.832 132.142 125.927 1.00 16.74  ? 76  LYS B C   1 
ATOM   4559 O  O   . LYS B 1 76  ? 138.413 131.193 126.604 1.00 16.74  ? 76  LYS B O   1 
ATOM   4560 C  CB  . LYS B 1 76  ? 141.313 132.466 125.704 1.00 16.74  ? 76  LYS B CB  1 
ATOM   4561 C  CG  . LYS B 1 76  ? 142.522 131.576 125.476 1.00 16.74  ? 76  LYS B CG  1 
ATOM   4562 C  CD  . LYS B 1 76  ? 143.449 131.578 126.678 1.00 16.74  ? 76  LYS B CD  1 
ATOM   4563 C  CE  . LYS B 1 76  ? 144.060 132.950 126.901 1.00 16.74  ? 76  LYS B CE  1 
ATOM   4564 N  NZ  . LYS B 1 76  ? 145.047 132.946 128.015 1.00 16.74  ? 76  LYS B NZ  1 
ATOM   4565 N  N   . VAL B 1 77  ? 138.253 133.345 125.951 1.00 15.42  ? 77  VAL B N   1 
ATOM   4566 C  CA  . VAL B 1 77  ? 137.055 133.575 126.754 1.00 15.42  ? 77  VAL B CA  1 
ATOM   4567 C  C   . VAL B 1 77  ? 135.926 132.672 126.286 1.00 15.42  ? 77  VAL B C   1 
ATOM   4568 O  O   . VAL B 1 77  ? 135.190 132.100 127.099 1.00 15.42  ? 77  VAL B O   1 
ATOM   4569 C  CB  . VAL B 1 77  ? 136.640 135.056 126.703 1.00 15.42  ? 77  VAL B CB  1 
ATOM   4570 C  CG1 . VAL B 1 77  ? 135.483 135.300 127.645 1.00 15.42  ? 77  VAL B CG1 1 
ATOM   4571 C  CG2 . VAL B 1 77  ? 137.796 135.944 127.063 1.00 15.42  ? 77  VAL B CG2 1 
ATOM   4572 N  N   . ALA B 1 78  ? 135.761 132.539 124.969 1.00 13.74  ? 78  ALA B N   1 
ATOM   4573 C  CA  . ALA B 1 78  ? 134.757 131.621 124.449 1.00 13.74  ? 78  ALA B CA  1 
ATOM   4574 C  C   . ALA B 1 78  ? 135.067 130.185 124.849 1.00 13.74  ? 78  ALA B C   1 
ATOM   4575 O  O   . ALA B 1 78  ? 134.178 129.451 125.293 1.00 13.74  ? 78  ALA B O   1 
ATOM   4576 C  CB  . ALA B 1 78  ? 134.667 131.749 122.932 1.00 13.74  ? 78  ALA B CB  1 
ATOM   4577 N  N   . SER B 1 79  ? 136.329 129.772 124.724 1.00 14.72  ? 79  SER B N   1 
ATOM   4578 C  CA  . SER B 1 79  ? 136.699 128.409 125.086 1.00 14.72  ? 79  SER B CA  1 
ATOM   4579 C  C   . SER B 1 79  ? 136.442 128.115 126.556 1.00 14.72  ? 79  SER B C   1 
ATOM   4580 O  O   . SER B 1 79  ? 136.227 126.953 126.915 1.00 14.72  ? 79  SER B O   1 
ATOM   4581 C  CB  . SER B 1 79  ? 138.170 128.157 124.758 1.00 14.72  ? 79  SER B CB  1 
ATOM   4582 O  OG  . SER B 1 79  ? 139.016 128.850 125.657 1.00 14.72  ? 79  SER B OG  1 
ATOM   4583 N  N   . ALA B 1 80  ? 136.453 129.136 127.411 1.00 12.86  ? 80  ALA B N   1 
ATOM   4584 C  CA  . ALA B 1 80  ? 136.194 128.940 128.831 1.00 12.86  ? 80  ALA B CA  1 
ATOM   4585 C  C   . ALA B 1 80  ? 134.715 128.781 129.163 1.00 12.86  ? 80  ALA B C   1 
ATOM   4586 O  O   . ALA B 1 80  ? 134.388 128.482 130.316 1.00 12.86  ? 80  ALA B O   1 
ATOM   4587 C  CB  . ALA B 1 80  ? 136.768 130.108 129.639 1.00 12.86  ? 80  ALA B CB  1 
ATOM   4588 N  N   . TYR B 1 81  ? 133.815 128.967 128.196 1.00 11.77  ? 81  TYR B N   1 
ATOM   4589 C  CA  . TYR B 1 81  ? 132.386 128.919 128.485 1.00 11.77  ? 81  TYR B CA  1 
ATOM   4590 C  C   . TYR B 1 81  ? 131.822 127.505 128.499 1.00 11.77  ? 81  TYR B C   1 
ATOM   4591 O  O   . TYR B 1 81  ? 130.811 127.266 129.165 1.00 11.77  ? 81  TYR B O   1 
ATOM   4592 C  CB  . TYR B 1 81  ? 131.611 129.763 127.473 1.00 11.77  ? 81  TYR B CB  1 
ATOM   4593 C  CG  . TYR B 1 81  ? 131.259 131.133 127.992 1.00 11.77  ? 81  TYR B CG  1 
ATOM   4594 C  CD1 . TYR B 1 81  ? 132.241 132.091 128.188 1.00 11.77  ? 81  TYR B CD1 1 
ATOM   4595 C  CD2 . TYR B 1 81  ? 129.950 131.466 128.298 1.00 11.77  ? 81  TYR B CD2 1 
ATOM   4596 C  CE1 . TYR B 1 81  ? 131.931 133.341 128.667 1.00 11.77  ? 81  TYR B CE1 1 
ATOM   4597 C  CE2 . TYR B 1 81  ? 129.629 132.717 128.778 1.00 11.77  ? 81  TYR B CE2 1 
ATOM   4598 C  CZ  . TYR B 1 81  ? 130.625 133.650 128.960 1.00 11.77  ? 81  TYR B CZ  1 
ATOM   4599 O  OH  . TYR B 1 81  ? 130.315 134.899 129.438 1.00 11.77  ? 81  TYR B OH  1 
ATOM   4600 N  N   . PHE B 1 82  ? 132.434 126.571 127.779 1.00 12.05  ? 82  PHE B N   1 
ATOM   4601 C  CA  . PHE B 1 82  ? 132.009 125.175 127.773 1.00 12.05  ? 82  PHE B CA  1 
ATOM   4602 C  C   . PHE B 1 82  ? 133.110 124.346 128.414 1.00 12.05  ? 82  PHE B C   1 
ATOM   4603 O  O   . PHE B 1 82  ? 134.215 124.246 127.870 1.00 12.05  ? 82  PHE B O   1 
ATOM   4604 C  CB  . PHE B 1 82  ? 131.715 124.694 126.356 1.00 12.05  ? 82  PHE B CB  1 
ATOM   4605 C  CG  . PHE B 1 82  ? 130.764 123.536 126.291 1.00 12.05  ? 82  PHE B CG  1 
ATOM   4606 C  CD1 . PHE B 1 82  ? 131.221 122.240 126.429 1.00 12.05  ? 82  PHE B CD1 1 
ATOM   4607 C  CD2 . PHE B 1 82  ? 129.415 123.744 126.078 1.00 12.05  ? 82  PHE B CD2 1 
ATOM   4608 C  CE1 . PHE B 1 82  ? 130.351 121.175 126.363 1.00 12.05  ? 82  PHE B CE1 1 
ATOM   4609 C  CE2 . PHE B 1 82  ? 128.540 122.682 126.011 1.00 12.05  ? 82  PHE B CE2 1 
ATOM   4610 C  CZ  . PHE B 1 82  ? 129.010 121.396 126.154 1.00 12.05  ? 82  PHE B CZ  1 
ATOM   4611 N  N   . LYS B 1 83  ? 132.809 123.751 129.564 1.00 14.85  ? 83  LYS B N   1 
ATOM   4612 C  CA  . LYS B 1 83  ? 133.798 122.961 130.281 1.00 14.85  ? 83  LYS B CA  1 
ATOM   4613 C  C   . LYS B 1 83  ? 133.251 121.582 130.618 1.00 14.85  ? 83  LYS B C   1 
ATOM   4614 O  O   . LYS B 1 83  ? 132.185 121.191 130.135 1.00 14.85  ? 83  LYS B O   1 
ATOM   4615 C  CB  . LYS B 1 83  ? 134.245 123.685 131.550 1.00 14.85  ? 83  LYS B CB  1 
ATOM   4616 C  CG  . LYS B 1 83  ? 135.217 124.822 131.293 1.00 14.85  ? 83  LYS B CG  1 
ATOM   4617 C  CD  . LYS B 1 83  ? 136.060 125.118 132.517 1.00 14.85  ? 83  LYS B CD  1 
ATOM   4618 C  CE  . LYS B 1 83  ? 136.957 126.319 132.286 1.00 14.85  ? 83  LYS B CE  1 
ATOM   4619 N  NZ  . LYS B 1 83  ? 137.790 126.623 133.478 1.00 14.85  ? 83  LYS B NZ  1 
ATOM   4620 N  N   . ASP B 1 84  ? 133.989 120.841 131.446 1.00 18.74  ? 84  ASP B N   1 
ATOM   4621 C  CA  . ASP B 1 84  ? 133.620 119.468 131.766 1.00 18.74  ? 84  ASP B CA  1 
ATOM   4622 C  C   . ASP B 1 84  ? 132.283 119.414 132.502 1.00 18.74  ? 84  ASP B C   1 
ATOM   4623 O  O   . ASP B 1 84  ? 131.488 118.479 132.305 1.00 18.74  ? 84  ASP B O   1 
ATOM   4624 C  CB  . ASP B 1 84  ? 134.738 118.844 132.601 1.00 18.74  ? 84  ASP B CB  1 
ATOM   4625 C  CG  . ASP B 1 84  ? 134.671 117.342 132.636 1.00 18.74  ? 84  ASP B CG  1 
ATOM   4626 O  OD1 . ASP B 1 84  ? 133.780 116.785 131.979 1.00 18.74  ? 84  ASP B OD1 1 
ATOM   4627 O  OD2 . ASP B 1 84  ? 135.512 116.719 133.319 1.00 18.74  ? 84  ASP B OD2 1 
ATOM   4628 N  N   . PHE B 1 85  ? 132.014 120.418 133.342 1.00 16.80  ? 85  PHE B N   1 
ATOM   4629 C  CA  . PHE B 1 85  ? 130.741 120.482 134.049 1.00 16.80  ? 85  PHE B CA  1 
ATOM   4630 C  C   . PHE B 1 85  ? 129.566 120.553 133.088 1.00 16.80  ? 85  PHE B C   1 
ATOM   4631 O  O   . PHE B 1 85  ? 128.486 120.052 133.403 1.00 16.80  ? 85  PHE B O   1 
ATOM   4632 C  CB  . PHE B 1 85  ? 130.717 121.686 134.989 1.00 16.80  ? 85  PHE B CB  1 
ATOM   4633 C  CG  . PHE B 1 85  ? 129.331 122.130 135.366 1.00 16.80  ? 85  PHE B CG  1 
ATOM   4634 C  CD1 . PHE B 1 85  ? 128.619 121.464 136.346 1.00 16.80  ? 85  PHE B CD1 1 
ATOM   4635 C  CD2 . PHE B 1 85  ? 128.737 123.209 134.734 1.00 16.80  ? 85  PHE B CD2 1 
ATOM   4636 C  CE1 . PHE B 1 85  ? 127.344 121.868 136.691 1.00 16.80  ? 85  PHE B CE1 1 
ATOM   4637 C  CE2 . PHE B 1 85  ? 127.463 123.615 135.074 1.00 16.80  ? 85  PHE B CE2 1 
ATOM   4638 C  CZ  . PHE B 1 85  ? 126.767 122.946 136.053 1.00 16.80  ? 85  PHE B CZ  1 
ATOM   4639 N  N   . HIS B 1 86  ? 129.744 121.175 131.923 1.00 15.06  ? 86  HIS B N   1 
ATOM   4640 C  CA  . HIS B 1 86  ? 128.636 121.272 130.979 1.00 15.06  ? 86  HIS B CA  1 
ATOM   4641 C  C   . HIS B 1 86  ? 128.299 119.914 130.376 1.00 15.06  ? 86  HIS B C   1 
ATOM   4642 O  O   . HIS B 1 86  ? 127.121 119.592 130.185 1.00 15.06  ? 86  HIS B O   1 
ATOM   4643 C  CB  . HIS B 1 86  ? 128.960 122.292 129.893 1.00 15.06  ? 86  HIS B CB  1 
ATOM   4644 C  CG  . HIS B 1 86  ? 128.983 123.703 130.388 1.00 15.06  ? 86  HIS B CG  1 
ATOM   4645 N  ND1 . HIS B 1 86  ? 129.977 124.186 131.211 1.00 15.06  ? 86  HIS B ND1 1 
ATOM   4646 C  CD2 . HIS B 1 86  ? 128.128 124.732 130.190 1.00 15.06  ? 86  HIS B CD2 1 
ATOM   4647 C  CE1 . HIS B 1 86  ? 129.738 125.454 131.490 1.00 15.06  ? 86  HIS B CE1 1 
ATOM   4648 N  NE2 . HIS B 1 86  ? 128.621 125.810 130.883 1.00 15.06  ? 86  HIS B NE2 1 
ATOM   4649 N  N   . LEU B 1 87  ? 129.314 119.102 130.073 1.00 16.37  ? 87  LEU B N   1 
ATOM   4650 C  CA  . LEU B 1 87  ? 129.048 117.737 129.632 1.00 16.37  ? 87  LEU B CA  1 
ATOM   4651 C  C   . LEU B 1 87  ? 128.359 116.937 130.728 1.00 16.37  ? 87  LEU B C   1 
ATOM   4652 O  O   . LEU B 1 87  ? 127.417 116.178 130.458 1.00 16.37  ? 87  LEU B O   1 
ATOM   4653 C  CB  . LEU B 1 87  ? 130.345 117.052 129.209 1.00 16.37  ? 87  LEU B CB  1 
ATOM   4654 C  CG  . LEU B 1 87  ? 131.098 117.635 128.016 1.00 16.37  ? 87  LEU B CG  1 
ATOM   4655 C  CD1 . LEU B 1 87  ? 132.467 116.996 127.911 1.00 16.37  ? 87  LEU B CD1 1 
ATOM   4656 C  CD2 . LEU B 1 87  ? 130.312 117.433 126.735 1.00 16.37  ? 87  LEU B CD2 1 
ATOM   4657 N  N   . LEU B 1 88  ? 128.813 117.097 131.975 1.00 30.81  ? 88  LEU B N   1 
ATOM   4658 C  CA  . LEU B 1 88  ? 128.134 116.431 133.084 1.00 30.81  ? 88  LEU B CA  1 
ATOM   4659 C  C   . LEU B 1 88  ? 126.673 116.855 133.167 1.00 30.81  ? 88  LEU B C   1 
ATOM   4660 O  O   . LEU B 1 88  ? 125.782 116.018 133.353 1.00 30.81  ? 88  LEU B O   1 
ATOM   4661 C  CB  . LEU B 1 88  ? 128.847 116.741 134.398 1.00 30.81  ? 88  LEU B CB  1 
ATOM   4662 C  CG  . LEU B 1 88  ? 128.205 116.174 135.662 1.00 30.81  ? 88  LEU B CG  1 
ATOM   4663 C  CD1 . LEU B 1 88  ? 128.367 114.670 135.700 1.00 30.81  ? 88  LEU B CD1 1 
ATOM   4664 C  CD2 . LEU B 1 88  ? 128.811 116.809 136.896 1.00 30.81  ? 88  LEU B CD2 1 
ATOM   4665 N  N   . LEU B 1 89  ? 126.415 118.155 133.030 1.00 30.81  ? 89  LEU B N   1 
ATOM   4666 C  CA  . LEU B 1 89  ? 125.057 118.676 133.116 1.00 30.81  ? 89  LEU B CA  1 
ATOM   4667 C  C   . LEU B 1 89  ? 124.182 118.129 132.001 1.00 30.81  ? 89  LEU B C   1 
ATOM   4668 O  O   . LEU B 1 89  ? 123.027 117.769 132.236 1.00 30.81  ? 89  LEU B O   1 
ATOM   4669 C  CB  . LEU B 1 89  ? 125.086 120.202 133.075 1.00 30.81  ? 89  LEU B CB  1 
ATOM   4670 C  CG  . LEU B 1 89  ? 123.741 120.924 133.117 1.00 30.81  ? 89  LEU B CG  1 
ATOM   4671 C  CD1 . LEU B 1 89  ? 123.029 120.656 134.431 1.00 30.81  ? 89  LEU B CD1 1 
ATOM   4672 C  CD2 . LEU B 1 89  ? 123.936 122.412 132.900 1.00 30.81  ? 89  LEU B CD2 1 
ATOM   4673 N  N   . ILE B 1 90  ? 124.710 118.064 130.778 1.00 18.48  ? 90  ILE B N   1 
ATOM   4674 C  CA  . ILE B 1 90  ? 123.936 117.520 129.663 1.00 18.48  ? 90  ILE B CA  1 
ATOM   4675 C  C   . ILE B 1 90  ? 123.596 116.057 129.920 1.00 18.48  ? 90  ILE B C   1 
ATOM   4676 O  O   . ILE B 1 90  ? 122.447 115.621 129.742 1.00 18.48  ? 90  ILE B O   1 
ATOM   4677 C  CB  . ILE B 1 90  ? 124.705 117.695 128.341 1.00 18.48  ? 90  ILE B CB  1 
ATOM   4678 C  CG1 . ILE B 1 90  ? 124.775 119.172 127.956 1.00 18.48  ? 90  ILE B CG1 1 
ATOM   4679 C  CG2 . ILE B 1 90  ? 124.055 116.888 127.234 1.00 18.48  ? 90  ILE B CG2 1 
ATOM   4680 C  CD1 . ILE B 1 90  ? 125.459 119.423 126.638 1.00 18.48  ? 90  ILE B CD1 1 
ATOM   4681 N  N   . GLY B 1 91  ? 124.590 115.278 130.355 1.00 30.81  ? 91  GLY B N   1 
ATOM   4682 C  CA  . GLY B 1 91  ? 124.345 113.872 130.627 1.00 30.81  ? 91  GLY B CA  1 
ATOM   4683 C  C   . GLY B 1 91  ? 123.308 113.656 131.711 1.00 30.81  ? 91  GLY B C   1 
ATOM   4684 O  O   . GLY B 1 91  ? 122.453 112.775 131.599 1.00 30.81  ? 91  GLY B O   1 
ATOM   4685 N  N   . VAL B 1 92  ? 123.368 114.455 132.778 1.00 19.89  ? 92  VAL B N   1 
ATOM   4686 C  CA  . VAL B 1 92  ? 122.405 114.308 133.866 1.00 19.89  ? 92  VAL B CA  1 
ATOM   4687 C  C   . VAL B 1 92  ? 121.024 114.797 133.441 1.00 19.89  ? 92  VAL B C   1 
ATOM   4688 O  O   . VAL B 1 92  ? 120.002 114.238 133.853 1.00 19.89  ? 92  VAL B O   1 
ATOM   4689 C  CB  . VAL B 1 92  ? 122.905 115.036 135.125 1.00 19.89  ? 92  VAL B CB  1 
ATOM   4690 C  CG1 . VAL B 1 92  ? 121.867 114.956 136.220 1.00 19.89  ? 92  VAL B CG1 1 
ATOM   4691 C  CG2 . VAL B 1 92  ? 124.206 114.430 135.598 1.00 19.89  ? 92  VAL B CG2 1 
ATOM   4692 N  N   . ILE B 1 93  ? 120.965 115.854 132.628 1.00 14.85  ? 93  ILE B N   1 
ATOM   4693 C  CA  . ILE B 1 93  ? 119.679 116.400 132.209 1.00 14.85  ? 93  ILE B CA  1 
ATOM   4694 C  C   . ILE B 1 93  ? 118.962 115.439 131.273 1.00 14.85  ? 93  ILE B C   1 
ATOM   4695 O  O   . ILE B 1 93  ? 117.728 115.386 131.262 1.00 14.85  ? 93  ILE B O   1 
ATOM   4696 C  CB  . ILE B 1 93  ? 119.870 117.791 131.577 1.00 14.85  ? 93  ILE B CB  1 
ATOM   4697 C  CG1 . ILE B 1 93  ? 120.109 118.833 132.668 1.00 14.85  ? 93  ILE B CG1 1 
ATOM   4698 C  CG2 . ILE B 1 93  ? 118.661 118.193 130.756 1.00 14.85  ? 93  ILE B CG2 1 
ATOM   4699 C  CD1 . ILE B 1 93  ? 118.990 118.917 133.675 1.00 14.85  ? 93  ILE B CD1 1 
ATOM   4700 N  N   . CYS B 1 94  ? 119.703 114.659 130.483 1.00 14.51  ? 94  CYS B N   1 
ATOM   4701 C  CA  . CYS B 1 94  ? 119.056 113.595 129.715 1.00 14.51  ? 94  CYS B CA  1 
ATOM   4702 C  C   . CYS B 1 94  ? 118.293 112.649 130.638 1.00 14.51  ? 94  CYS B C   1 
ATOM   4703 O  O   . CYS B 1 94  ? 117.114 112.338 130.409 1.00 14.51  ? 94  CYS B O   1 
ATOM   4704 C  CB  . CYS B 1 94  ? 120.096 112.826 128.900 1.00 14.51  ? 94  CYS B CB  1 
ATOM   4705 S  SG  . CYS B 1 94  ? 120.914 113.785 127.612 1.00 14.51  ? 94  CYS B SG  1 
ATOM   4706 N  N   . LEU B 1 95  ? 118.951 112.203 131.710 1.00 12.66  ? 95  LEU B N   1 
ATOM   4707 C  CA  . LEU B 1 95  ? 118.314 111.307 132.667 1.00 12.66  ? 95  LEU B CA  1 
ATOM   4708 C  C   . LEU B 1 95  ? 117.145 111.983 133.371 1.00 12.66  ? 95  LEU B C   1 
ATOM   4709 O  O   . LEU B 1 95  ? 116.119 111.348 133.627 1.00 12.66  ? 95  LEU B O   1 
ATOM   4710 C  CB  . LEU B 1 95  ? 119.349 110.822 133.679 1.00 12.66  ? 95  LEU B CB  1 
ATOM   4711 C  CG  . LEU B 1 95  ? 118.864 110.178 134.975 1.00 12.66  ? 95  LEU B CG  1 
ATOM   4712 C  CD1 . LEU B 1 95  ? 118.079 108.910 134.696 1.00 12.66  ? 95  LEU B CD1 1 
ATOM   4713 C  CD2 . LEU B 1 95  ? 120.055 109.889 135.865 1.00 12.66  ? 95  LEU B CD2 1 
ATOM   4714 N  N   . ALA B 1 96  ? 117.288 113.265 133.707 1.00 12.50  ? 96  ALA B N   1 
ATOM   4715 C  CA  . ALA B 1 96  ? 116.203 113.982 134.373 1.00 12.50  ? 96  ALA B CA  1 
ATOM   4716 C  C   . ALA B 1 96  ? 114.986 114.116 133.464 1.00 12.50  ? 96  ALA B C   1 
ATOM   4717 O  O   . ALA B 1 96  ? 113.842 113.992 133.920 1.00 12.50  ? 96  ALA B O   1 
ATOM   4718 C  CB  . ALA B 1 96  ? 116.686 115.355 134.833 1.00 12.50  ? 96  ALA B CB  1 
ATOM   4719 N  N   . THR B 1 97  ? 115.214 114.382 132.177 1.00 12.39  ? 97  THR B N   1 
ATOM   4720 C  CA  . THR B 1 97  ? 114.118 114.426 131.217 1.00 12.39  ? 97  THR B CA  1 
ATOM   4721 C  C   . THR B 1 97  ? 113.428 113.076 131.119 1.00 12.39  ? 97  THR B C   1 
ATOM   4722 O  O   . THR B 1 97  ? 112.195 113.001 131.083 1.00 12.39  ? 97  THR B O   1 
ATOM   4723 C  CB  . THR B 1 97  ? 114.635 114.851 129.844 1.00 12.39  ? 97  THR B CB  1 
ATOM   4724 O  OG1 . THR B 1 97  ? 115.549 115.944 129.990 1.00 12.39  ? 97  THR B OG1 1 
ATOM   4725 C  CG2 . THR B 1 97  ? 113.485 115.270 128.949 1.00 12.39  ? 97  THR B CG2 1 
ATOM   4726 N  N   . SER B 1 98  ? 114.209 111.995 131.072 1.00 11.49  ? 98  SER B N   1 
ATOM   4727 C  CA  . SER B 1 98  ? 113.606 110.667 131.030 1.00 11.49  ? 98  SER B CA  1 
ATOM   4728 C  C   . SER B 1 98  ? 112.828 110.371 132.307 1.00 11.49  ? 98  SER B C   1 
ATOM   4729 O  O   . SER B 1 98  ? 111.796 109.691 132.271 1.00 11.49  ? 98  SER B O   1 
ATOM   4730 C  CB  . SER B 1 98  ? 114.680 109.611 130.801 1.00 11.49  ? 98  SER B CB  1 
ATOM   4731 O  OG  . SER B 1 98  ? 114.099 108.333 130.622 1.00 11.49  ? 98  SER B OG  1 
ATOM   4732 N  N   . ILE B 1 99  ? 113.317 110.862 133.445 1.00 13.25  ? 99  ILE B N   1 
ATOM   4733 C  CA  . ILE B 1 99  ? 112.643 110.634 134.720 1.00 13.25  ? 99  ILE B CA  1 
ATOM   4734 C  C   . ILE B 1 99  ? 111.300 111.350 134.749 1.00 13.25  ? 99  ILE B C   1 
ATOM   4735 O  O   . ILE B 1 99  ? 110.274 110.766 135.116 1.00 13.25  ? 99  ILE B O   1 
ATOM   4736 C  CB  . ILE B 1 99  ? 113.540 111.086 135.886 1.00 13.25  ? 99  ILE B CB  1 
ATOM   4737 C  CG1 . ILE B 1 99  ? 114.595 110.028 136.199 1.00 13.25  ? 99  ILE B CG1 1 
ATOM   4738 C  CG2 . ILE B 1 99  ? 112.712 111.376 137.120 1.00 13.25  ? 99  ILE B CG2 1 
ATOM   4739 C  CD1 . ILE B 1 99  ? 115.578 110.454 137.258 1.00 13.25  ? 99  ILE B CD1 1 
ATOM   4740 N  N   . GLU B 1 100 ? 111.283 112.625 134.360 1.00 17.48  ? 100 GLU B N   1 
ATOM   4741 C  CA  . GLU B 1 100 ? 110.054 113.404 134.474 1.00 17.48  ? 100 GLU B CA  1 
ATOM   4742 C  C   . GLU B 1 100 ? 109.049 113.058 133.381 1.00 17.48  ? 100 GLU B C   1 
ATOM   4743 O  O   . GLU B 1 100 ? 107.838 113.074 133.627 1.00 17.48  ? 100 GLU B O   1 
ATOM   4744 C  CB  . GLU B 1 100 ? 110.372 114.900 134.467 1.00 17.48  ? 100 GLU B CB  1 
ATOM   4745 C  CG  . GLU B 1 100 ? 109.196 115.778 134.077 1.00 17.48  ? 100 GLU B CG  1 
ATOM   4746 C  CD  . GLU B 1 100 ? 109.329 117.194 134.587 1.00 17.48  ? 100 GLU B CD  1 
ATOM   4747 O  OE1 . GLU B 1 100 ? 110.418 117.545 135.080 1.00 17.48  ? 100 GLU B OE1 1 
ATOM   4748 O  OE2 . GLU B 1 100 ? 108.345 117.957 134.495 1.00 17.48  ? 100 GLU B OE2 1 
ATOM   4749 N  N   . LYS B 1 101 ? 109.524 112.729 132.178 1.00 13.33  ? 101 LYS B N   1 
ATOM   4750 C  CA  . LYS B 1 101 ? 108.609 112.466 131.071 1.00 13.33  ? 101 LYS B CA  1 
ATOM   4751 C  C   . LYS B 1 101 ? 107.717 111.265 131.358 1.00 13.33  ? 101 LYS B C   1 
ATOM   4752 O  O   . LYS B 1 101 ? 106.526 111.274 131.028 1.00 13.33  ? 101 LYS B O   1 
ATOM   4753 C  CB  . LYS B 1 101 ? 109.398 112.253 129.779 1.00 13.33  ? 101 LYS B CB  1 
ATOM   4754 C  CG  . LYS B 1 101 ? 108.566 111.709 128.633 1.00 13.33  ? 101 LYS B CG  1 
ATOM   4755 C  CD  . LYS B 1 101 ? 109.414 111.425 127.409 1.00 13.33  ? 101 LYS B CD  1 
ATOM   4756 C  CE  . LYS B 1 101 ? 108.550 110.970 126.247 1.00 13.33  ? 101 LYS B CE  1 
ATOM   4757 N  NZ  . LYS B 1 101 ? 109.277 111.034 124.951 1.00 13.33  ? 101 LYS B NZ  1 
ATOM   4758 N  N   . TRP B 1 102 ? 108.271 110.226 131.977 1.00 14.40  ? 102 TRP B N   1 
ATOM   4759 C  CA  . TRP B 1 102 ? 107.550 108.989 132.233 1.00 14.40  ? 102 TRP B CA  1 
ATOM   4760 C  C   . TRP B 1 102 ? 106.985 108.913 133.645 1.00 14.40  ? 102 TRP B C   1 
ATOM   4761 O  O   . TRP B 1 102 ? 106.567 107.833 134.075 1.00 14.40  ? 102 TRP B O   1 
ATOM   4762 C  CB  . TRP B 1 102 ? 108.460 107.794 131.958 1.00 14.40  ? 102 TRP B CB  1 
ATOM   4763 C  CG  . TRP B 1 102 ? 108.977 107.780 130.556 1.00 14.40  ? 102 TRP B CG  1 
ATOM   4764 C  CD1 . TRP B 1 102 ? 110.262 107.987 130.155 1.00 14.40  ? 102 TRP B CD1 1 
ATOM   4765 C  CD2 . TRP B 1 102 ? 108.217 107.552 129.365 1.00 14.40  ? 102 TRP B CD2 1 
ATOM   4766 N  NE1 . TRP B 1 102 ? 110.350 107.903 128.788 1.00 14.40  ? 102 TRP B NE1 1 
ATOM   4767 C  CE2 . TRP B 1 102 ? 109.107 107.635 128.279 1.00 14.40  ? 102 TRP B CE2 1 
ATOM   4768 C  CE3 . TRP B 1 102 ? 106.869 107.284 129.112 1.00 14.40  ? 102 TRP B CE3 1 
ATOM   4769 C  CZ2 . TRP B 1 102 ? 108.695 107.459 126.962 1.00 14.40  ? 102 TRP B CZ2 1 
ATOM   4770 C  CZ3 . TRP B 1 102 ? 106.462 107.112 127.804 1.00 14.40  ? 102 TRP B CZ3 1 
ATOM   4771 C  CH2 . TRP B 1 102 ? 107.371 107.199 126.746 1.00 14.40  ? 102 TRP B CH2 1 
ATOM   4772 N  N   . ASN B 1 103 ? 106.969 110.031 134.372 1.00 18.36  ? 103 ASN B N   1 
ATOM   4773 C  CA  . ASN B 1 103 ? 106.340 110.122 135.691 1.00 18.36  ? 103 ASN B CA  1 
ATOM   4774 C  C   . ASN B 1 103 ? 106.954 109.141 136.686 1.00 18.36  ? 103 ASN B C   1 
ATOM   4775 O  O   . ASN B 1 103 ? 106.263 108.582 137.539 1.00 18.36  ? 103 ASN B O   1 
ATOM   4776 C  CB  . ASN B 1 103 ? 104.827 109.919 135.597 1.00 18.36  ? 103 ASN B CB  1 
ATOM   4777 C  CG  . ASN B 1 103 ? 104.117 111.113 134.999 1.00 18.36  ? 103 ASN B CG  1 
ATOM   4778 O  OD1 . ASN B 1 103 ? 104.419 112.258 135.331 1.00 18.36  ? 103 ASN B OD1 1 
ATOM   4779 N  ND2 . ASN B 1 103 ? 103.167 110.853 134.111 1.00 18.36  ? 103 ASN B ND2 1 
ATOM   4780 N  N   . LEU B 1 104 ? 108.263 108.922 136.574 1.00 18.49  ? 104 LEU B N   1 
ATOM   4781 C  CA  . LEU B 1 104 ? 108.961 108.155 137.600 1.00 18.49  ? 104 LEU B CA  1 
ATOM   4782 C  C   . LEU B 1 104 ? 109.152 108.985 138.862 1.00 18.49  ? 104 LEU B C   1 
ATOM   4783 O  O   . LEU B 1 104 ? 109.059 108.462 139.980 1.00 18.49  ? 104 LEU B O   1 
ATOM   4784 C  CB  . LEU B 1 104 ? 110.307 107.669 137.069 1.00 18.49  ? 104 LEU B CB  1 
ATOM   4785 C  CG  . LEU B 1 104 ? 111.128 106.808 138.027 1.00 18.49  ? 104 LEU B CG  1 
ATOM   4786 C  CD1 . LEU B 1 104 ? 110.304 105.640 138.536 1.00 18.49  ? 104 LEU B CD1 1 
ATOM   4787 C  CD2 . LEU B 1 104 ? 112.393 106.320 137.350 1.00 18.49  ? 104 LEU B CD2 1 
ATOM   4788 N  N   . HIS B 1 105 ? 109.415 110.284 138.698 1.00 22.86  ? 105 HIS B N   1 
ATOM   4789 C  CA  . HIS B 1 105 ? 109.605 111.160 139.848 1.00 22.86  ? 105 HIS B CA  1 
ATOM   4790 C  C   . HIS B 1 105 ? 108.340 111.242 140.691 1.00 22.86  ? 105 HIS B C   1 
ATOM   4791 O  O   . HIS B 1 105 ? 108.408 111.234 141.924 1.00 22.86  ? 105 HIS B O   1 
ATOM   4792 C  CB  . HIS B 1 105 ? 110.035 112.550 139.377 1.00 22.86  ? 105 HIS B CB  1 
ATOM   4793 C  CG  . HIS B 1 105 ? 108.963 113.301 138.652 1.00 22.86  ? 105 HIS B CG  1 
ATOM   4794 N  ND1 . HIS B 1 105 ? 108.583 112.998 137.363 1.00 22.86  ? 105 HIS B ND1 1 
ATOM   4795 C  CD2 . HIS B 1 105 ? 108.197 114.352 139.031 1.00 22.86  ? 105 HIS B CD2 1 
ATOM   4796 C  CE1 . HIS B 1 105 ? 107.624 113.823 136.982 1.00 22.86  ? 105 HIS B CE1 1 
ATOM   4797 N  NE2 . HIS B 1 105 ? 107.372 114.655 137.976 1.00 22.86  ? 105 HIS B NE2 1 
ATOM   4798 N  N   . LYS B 1 106 ? 107.175 111.315 140.043 1.00 25.52  ? 106 LYS B N   1 
ATOM   4799 C  CA  . LYS B 1 106 ? 105.919 111.355 140.783 1.00 25.52  ? 106 LYS B CA  1 
ATOM   4800 C  C   . LYS B 1 106 ? 105.707 110.074 141.578 1.00 25.52  ? 106 LYS B C   1 
ATOM   4801 O  O   . LYS B 1 106 ? 105.289 110.121 142.740 1.00 25.52  ? 106 LYS B O   1 
ATOM   4802 C  CB  . LYS B 1 106 ? 104.752 111.588 139.826 1.00 25.52  ? 106 LYS B CB  1 
ATOM   4803 C  CG  . LYS B 1 106 ? 103.401 111.647 140.511 1.00 25.52  ? 106 LYS B CG  1 
ATOM   4804 C  CD  . LYS B 1 106 ? 102.280 111.865 139.513 1.00 25.52  ? 106 LYS B CD  1 
ATOM   4805 C  CE  . LYS B 1 106 ? 100.926 111.836 140.198 1.00 25.52  ? 106 LYS B CE  1 
ATOM   4806 N  NZ  . LYS B 1 106 ? 99.808  112.002 139.231 1.00 25.52  ? 106 LYS B NZ  1 
ATOM   4807 N  N   . ARG B 1 107 ? 105.989 108.920 140.970 1.00 23.96  ? 107 ARG B N   1 
ATOM   4808 C  CA  . ARG B 1 107 ? 105.825 107.655 141.679 1.00 23.96  ? 107 ARG B CA  1 
ATOM   4809 C  C   . ARG B 1 107 ? 106.765 107.563 142.873 1.00 23.96  ? 107 ARG B C   1 
ATOM   4810 O  O   . ARG B 1 107 ? 106.355 107.149 143.965 1.00 23.96  ? 107 ARG B O   1 
ATOM   4811 C  CB  . ARG B 1 107 ? 106.058 106.483 140.728 1.00 23.96  ? 107 ARG B CB  1 
ATOM   4812 C  CG  . ARG B 1 107 ? 106.026 105.129 141.412 1.00 23.96  ? 107 ARG B CG  1 
ATOM   4813 C  CD  . ARG B 1 107 ? 106.205 103.997 140.419 1.00 23.96  ? 107 ARG B CD  1 
ATOM   4814 N  NE  . ARG B 1 107 ? 104.944 103.328 140.124 1.00 23.96  ? 107 ARG B NE  1 
ATOM   4815 C  CZ  . ARG B 1 107 ? 104.232 103.525 139.024 1.00 23.96  ? 107 ARG B CZ  1 
ATOM   4816 N  NH1 . ARG B 1 107 ? 104.634 104.361 138.081 1.00 23.96  ? 107 ARG B NH1 1 
ATOM   4817 N  NH2 . ARG B 1 107 ? 103.089 102.866 138.865 1.00 23.96  ? 107 ARG B NH2 1 
ATOM   4818 N  N   . ILE B 1 108 ? 108.030 107.948 142.687 1.00 25.18  ? 108 ILE B N   1 
ATOM   4819 C  CA  . ILE B 1 108 ? 108.986 107.896 143.789 1.00 25.18  ? 108 ILE B CA  1 
ATOM   4820 C  C   . ILE B 1 108 ? 108.564 108.843 144.905 1.00 25.18  ? 108 ILE B C   1 
ATOM   4821 O  O   . ILE B 1 108 ? 108.629 108.497 146.092 1.00 25.18  ? 108 ILE B O   1 
ATOM   4822 C  CB  . ILE B 1 108 ? 110.406 108.210 143.283 1.00 25.18  ? 108 ILE B CB  1 
ATOM   4823 C  CG1 . ILE B 1 108 ? 110.870 107.137 142.299 1.00 25.18  ? 108 ILE B CG1 1 
ATOM   4824 C  CG2 . ILE B 1 108 ? 111.377 108.295 144.442 1.00 25.18  ? 108 ILE B CG2 1 
ATOM   4825 C  CD1 . ILE B 1 108 ? 110.549 105.726 142.737 1.00 25.18  ? 108 ILE B CD1 1 
ATOM   4826 N  N   . ALA B 1 109 ? 108.118 110.048 144.543 1.00 29.04  ? 109 ALA B N   1 
ATOM   4827 C  CA  . ALA B 1 109 ? 107.680 111.015 145.542 1.00 29.04  ? 109 ALA B CA  1 
ATOM   4828 C  C   . ALA B 1 109 ? 106.480 110.503 146.323 1.00 29.04  ? 109 ALA B C   1 
ATOM   4829 O  O   . ALA B 1 109 ? 106.431 110.630 147.552 1.00 29.04  ? 109 ALA B O   1 
ATOM   4830 C  CB  . ALA B 1 109 ? 107.343 112.341 144.867 1.00 29.04  ? 109 ALA B CB  1 
ATOM   4831 N  N   . LEU B 1 110 ? 105.497 109.930 145.627 1.00 30.77  ? 110 LEU B N   1 
ATOM   4832 C  CA  . LEU B 1 110 ? 104.318 109.417 146.311 1.00 30.77  ? 110 LEU B CA  1 
ATOM   4833 C  C   . LEU B 1 110 ? 104.676 108.259 147.230 1.00 30.77  ? 110 LEU B C   1 
ATOM   4834 O  O   . LEU B 1 110 ? 104.174 108.176 148.356 1.00 30.77  ? 110 LEU B O   1 
ATOM   4835 C  CB  . LEU B 1 110 ? 103.263 108.994 145.293 1.00 30.77  ? 110 LEU B CB  1 
ATOM   4836 C  CG  . LEU B 1 110 ? 102.517 110.148 144.624 1.00 30.77  ? 110 LEU B CG  1 
ATOM   4837 C  CD1 . LEU B 1 110 ? 101.311 109.634 143.873 1.00 30.77  ? 110 LEU B CD1 1 
ATOM   4838 C  CD2 . LEU B 1 110 ? 102.106 111.179 145.653 1.00 30.77  ? 110 LEU B CD2 1 
ATOM   4839 N  N   . LYS B 1 111 ? 105.550 107.357 146.774 1.00 34.67  ? 111 LYS B N   1 
ATOM   4840 C  CA  . LYS B 1 111 ? 105.965 106.249 147.627 1.00 34.67  ? 111 LYS B CA  1 
ATOM   4841 C  C   . LYS B 1 111 ? 106.682 106.753 148.872 1.00 34.67  ? 111 LYS B C   1 
ATOM   4842 O  O   . LYS B 1 111 ? 106.424 106.275 149.985 1.00 34.67  ? 111 LYS B O   1 
ATOM   4843 C  CB  . LYS B 1 111 ? 106.860 105.289 146.845 1.00 34.67  ? 111 LYS B CB  1 
ATOM   4844 C  CG  . LYS B 1 111 ? 107.077 103.949 147.526 1.00 34.67  ? 111 LYS B CG  1 
ATOM   4845 C  CD  . LYS B 1 111 ? 107.335 102.848 146.509 1.00 34.67  ? 111 LYS B CD  1 
ATOM   4846 C  CE  . LYS B 1 111 ? 108.698 103.007 145.851 1.00 34.67  ? 111 LYS B CE  1 
ATOM   4847 N  NZ  . LYS B 1 111 ? 108.841 102.152 144.639 1.00 34.67  ? 111 LYS B NZ  1 
ATOM   4848 N  N   . MET B 1 112 ? 107.579 107.728 148.707 1.00 39.24  ? 112 MET B N   1 
ATOM   4849 C  CA  . MET B 1 112 ? 108.293 108.266 149.859 1.00 39.24  ? 112 MET B CA  1 
ATOM   4850 C  C   . MET B 1 112 ? 107.337 108.942 150.833 1.00 39.24  ? 112 MET B C   1 
ATOM   4851 O  O   . MET B 1 112 ? 107.444 108.749 152.048 1.00 39.24  ? 112 MET B O   1 
ATOM   4852 C  CB  . MET B 1 112 ? 109.375 109.243 149.403 1.00 39.24  ? 112 MET B CB  1 
ATOM   4853 C  CG  . MET B 1 112 ? 110.192 109.815 150.546 1.00 39.24  ? 112 MET B CG  1 
ATOM   4854 S  SD  . MET B 1 112 ? 111.364 111.081 150.029 1.00 39.24  ? 112 MET B SD  1 
ATOM   4855 C  CE  . MET B 1 112 ? 111.612 111.947 151.577 1.00 39.24  ? 112 MET B CE  1 
ATOM   4856 N  N   . VAL B 1 113 ? 106.386 109.725 150.318 1.00 38.52  ? 113 VAL B N   1 
ATOM   4857 C  CA  . VAL B 1 113 ? 105.425 110.403 151.185 1.00 38.52  ? 113 VAL B CA  1 
ATOM   4858 C  C   . VAL B 1 113 ? 104.568 109.388 151.931 1.00 38.52  ? 113 VAL B C   1 
ATOM   4859 O  O   . VAL B 1 113 ? 104.265 109.563 153.118 1.00 38.52  ? 113 VAL B O   1 
ATOM   4860 C  CB  . VAL B 1 113 ? 104.568 111.386 150.366 1.00 38.52  ? 113 VAL B CB  1 
ATOM   4861 C  CG1 . VAL B 1 113 ? 103.341 111.813 151.153 1.00 38.52  ? 113 VAL B CG1 1 
ATOM   4862 C  CG2 . VAL B 1 113 ? 105.392 112.597 149.972 1.00 38.52  ? 113 VAL B CG2 1 
ATOM   4863 N  N   . MET B 1 114 ? 104.163 108.312 151.252 1.00 44.96  ? 114 MET B N   1 
ATOM   4864 C  CA  . MET B 1 114 ? 103.427 107.249 151.929 1.00 44.96  ? 114 MET B CA  1 
ATOM   4865 C  C   . MET B 1 114 ? 104.259 106.623 153.039 1.00 44.96  ? 114 MET B C   1 
ATOM   4866 O  O   . MET B 1 114 ? 103.745 106.349 154.129 1.00 44.96  ? 114 MET B O   1 
ATOM   4867 C  CB  . MET B 1 114 ? 102.997 106.177 150.928 1.00 44.96  ? 114 MET B CB  1 
ATOM   4868 C  CG  . MET B 1 114 ? 101.972 106.626 149.910 1.00 44.96  ? 114 MET B CG  1 
ATOM   4869 S  SD  . MET B 1 114 ? 101.601 105.317 148.729 1.00 44.96  ? 114 MET B SD  1 
ATOM   4870 C  CE  . MET B 1 114 ? 100.697 104.169 149.762 1.00 44.96  ? 114 MET B CE  1 
ATOM   4871 N  N   . MET B 1 115 ? 105.547 106.389 152.783 1.00 51.38  ? 115 MET B N   1 
ATOM   4872 C  CA  . MET B 1 115 ? 106.377 105.711 153.773 1.00 51.38  ? 115 MET B CA  1 
ATOM   4873 C  C   . MET B 1 115 ? 106.600 106.587 155.001 1.00 51.38  ? 115 MET B C   1 
ATOM   4874 O  O   . MET B 1 115 ? 106.170 106.245 156.108 1.00 51.38  ? 115 MET B O   1 
ATOM   4875 C  CB  . MET B 1 115 ? 107.712 105.305 153.147 1.00 51.38  ? 115 MET B CB  1 
ATOM   4876 C  CG  . MET B 1 115 ? 107.641 104.044 152.304 1.00 51.38  ? 115 MET B CG  1 
ATOM   4877 S  SD  . MET B 1 115 ? 109.221 103.181 152.213 1.00 51.38  ? 115 MET B SD  1 
ATOM   4878 C  CE  . MET B 1 115 ? 108.992 101.922 153.466 1.00 51.38  ? 115 MET B CE  1 
ATOM   4879 N  N   . VAL B 1 116 ? 107.260 107.731 154.823 1.00 52.97  ? 116 VAL B N   1 
ATOM   4880 C  CA  . VAL B 1 116 ? 107.594 108.640 155.915 1.00 52.97  ? 116 VAL B CA  1 
ATOM   4881 C  C   . VAL B 1 116 ? 107.512 110.071 155.400 1.00 52.97  ? 116 VAL B C   1 
ATOM   4882 O  O   . VAL B 1 116 ? 107.403 110.318 154.200 1.00 52.97  ? 116 VAL B O   1 
ATOM   4883 C  CB  . VAL B 1 116 ? 109.002 108.372 156.494 1.00 52.97  ? 116 VAL B CB  1 
ATOM   4884 C  CG1 . VAL B 1 116 ? 109.043 107.054 157.258 1.00 52.97  ? 116 VAL B CG1 1 
ATOM   4885 C  CG2 . VAL B 1 116 ? 110.038 108.385 155.382 1.00 52.97  ? 116 VAL B CG2 1 
ATOM   4886 N  N   . GLY B 1 117 ? 107.574 111.026 156.321 1.00 59.26  ? 117 GLY B N   1 
ATOM   4887 C  CA  . GLY B 1 117 ? 107.720 112.415 155.934 1.00 59.26  ? 117 GLY B CA  1 
ATOM   4888 C  C   . GLY B 1 117 ? 106.464 113.108 155.445 1.00 59.26  ? 117 GLY B C   1 
ATOM   4889 O  O   . GLY B 1 117 ? 106.373 113.479 154.272 1.00 59.26  ? 117 GLY B O   1 
ATOM   4890 N  N   . VAL B 1 118 ? 105.486 113.283 156.330 1.00 57.19  ? 118 VAL B N   1 
ATOM   4891 C  CA  . VAL B 1 118 ? 104.330 114.120 156.031 1.00 57.19  ? 118 VAL B CA  1 
ATOM   4892 C  C   . VAL B 1 118 ? 104.583 115.500 156.626 1.00 57.19  ? 118 VAL B C   1 
ATOM   4893 O  O   . VAL B 1 118 ? 104.208 116.523 156.042 1.00 57.19  ? 118 VAL B O   1 
ATOM   4894 C  CB  . VAL B 1 118 ? 103.030 113.500 156.574 1.00 57.19  ? 118 VAL B CB  1 
ATOM   4895 C  CG1 . VAL B 1 118 ? 101.850 114.426 156.324 1.00 57.19  ? 118 VAL B CG1 1 
ATOM   4896 C  CG2 . VAL B 1 118 ? 102.792 112.137 155.944 1.00 57.19  ? 118 VAL B CG2 1 
ATOM   4897 N  N   . ASN B 1 119 ? 105.228 115.531 157.787 1.00 52.41  ? 119 ASN B N   1 
ATOM   4898 C  CA  . ASN B 1 119 ? 105.570 116.793 158.433 1.00 52.41  ? 119 ASN B CA  1 
ATOM   4899 C  C   . ASN B 1 119 ? 106.695 117.478 157.662 1.00 52.41  ? 119 ASN B C   1 
ATOM   4900 O  O   . ASN B 1 119 ? 107.699 116.831 157.342 1.00 52.41  ? 119 ASN B O   1 
ATOM   4901 C  CB  . ASN B 1 119 ? 105.995 116.536 159.877 1.00 52.41  ? 119 ASN B CB  1 
ATOM   4902 C  CG  . ASN B 1 119 ? 105.817 117.748 160.771 1.00 52.41  ? 119 ASN B CG  1 
ATOM   4903 O  OD1 . ASN B 1 119 ? 105.193 118.734 160.389 1.00 52.41  ? 119 ASN B OD1 1 
ATOM   4904 N  ND2 . ASN B 1 119 ? 106.372 117.677 161.975 1.00 52.41  ? 119 ASN B ND2 1 
ATOM   4905 N  N   . PRO B 1 120 ? 106.564 118.767 157.334 1.00 46.05  ? 120 PRO B N   1 
ATOM   4906 C  CA  . PRO B 1 120 ? 107.633 119.441 156.576 1.00 46.05  ? 120 PRO B CA  1 
ATOM   4907 C  C   . PRO B 1 120 ? 108.985 119.450 157.270 1.00 46.05  ? 120 PRO B C   1 
ATOM   4908 O  O   . PRO B 1 120 ? 110.013 119.398 156.584 1.00 46.05  ? 120 PRO B O   1 
ATOM   4909 C  CB  . PRO B 1 120 ? 107.087 120.866 156.391 1.00 46.05  ? 120 PRO B CB  1 
ATOM   4910 C  CG  . PRO B 1 120 ? 105.957 120.993 157.367 1.00 46.05  ? 120 PRO B CG  1 
ATOM   4911 C  CD  . PRO B 1 120 ? 105.380 119.625 157.486 1.00 46.05  ? 120 PRO B CD  1 
ATOM   4912 N  N   . ALA B 1 121 ? 109.025 119.522 158.602 1.00 43.33  ? 121 ALA B N   1 
ATOM   4913 C  CA  . ALA B 1 121 ? 110.310 119.560 159.296 1.00 43.33  ? 121 ALA B CA  1 
ATOM   4914 C  C   . ALA B 1 121 ? 111.066 118.248 159.130 1.00 43.33  ? 121 ALA B C   1 
ATOM   4915 O  O   . ALA B 1 121 ? 112.244 118.241 158.750 1.00 43.33  ? 121 ALA B O   1 
ATOM   4916 C  CB  . ALA B 1 121 ? 110.098 119.876 160.776 1.00 43.33  ? 121 ALA B CB  1 
ATOM   4917 N  N   . TRP B 1 122 ? 110.403 117.124 159.406 1.00 49.83  ? 122 TRP B N   1 
ATOM   4918 C  CA  . TRP B 1 122 ? 111.033 115.828 159.181 1.00 49.83  ? 122 TRP B CA  1 
ATOM   4919 C  C   . TRP B 1 122 ? 111.304 115.583 157.706 1.00 49.83  ? 122 TRP B C   1 
ATOM   4920 O  O   . TRP B 1 122 ? 112.277 114.908 157.367 1.00 49.83  ? 122 TRP B O   1 
ATOM   4921 C  CB  . TRP B 1 122 ? 110.171 114.705 159.755 1.00 49.83  ? 122 TRP B CB  1 
ATOM   4922 C  CG  . TRP B 1 122 ? 109.740 114.937 161.166 1.00 49.83  ? 122 TRP B CG  1 
ATOM   4923 C  CD1 . TRP B 1 122 ? 108.463 115.070 161.622 1.00 49.83  ? 122 TRP B CD1 1 
ATOM   4924 C  CD2 . TRP B 1 122 ? 110.589 115.039 162.314 1.00 49.83  ? 122 TRP B CD2 1 
ATOM   4925 N  NE1 . TRP B 1 122 ? 108.464 115.262 162.981 1.00 49.83  ? 122 TRP B NE1 1 
ATOM   4926 C  CE2 . TRP B 1 122 ? 109.758 115.246 163.430 1.00 49.83  ? 122 TRP B CE2 1 
ATOM   4927 C  CE3 . TRP B 1 122 ? 111.973 114.980 162.505 1.00 49.83  ? 122 TRP B CE3 1 
ATOM   4928 C  CZ2 . TRP B 1 122 ? 110.264 115.392 164.718 1.00 49.83  ? 122 TRP B CZ2 1 
ATOM   4929 C  CZ3 . TRP B 1 122 ? 112.472 115.127 163.783 1.00 49.83  ? 122 TRP B CZ3 1 
ATOM   4930 C  CH2 . TRP B 1 122 ? 111.620 115.331 164.873 1.00 49.83  ? 122 TRP B CH2 1 
ATOM   4931 N  N   . LEU B 1 123 ? 110.466 116.119 156.817 1.00 40.79  ? 123 LEU B N   1 
ATOM   4932 C  CA  . LEU B 1 123 ? 110.729 115.986 155.388 1.00 40.79  ? 123 LEU B CA  1 
ATOM   4933 C  C   . LEU B 1 123 ? 112.032 116.674 155.003 1.00 40.79  ? 123 LEU B C   1 
ATOM   4934 O  O   . LEU B 1 123 ? 112.862 116.107 154.282 1.00 40.79  ? 123 LEU B O   1 
ATOM   4935 C  CB  . LEU B 1 123 ? 109.565 116.565 154.588 1.00 40.79  ? 123 LEU B CB  1 
ATOM   4936 C  CG  . LEU B 1 123 ? 109.557 116.199 153.108 1.00 40.79  ? 123 LEU B CG  1 
ATOM   4937 C  CD1 . LEU B 1 123 ? 109.066 114.775 152.908 1.00 40.79  ? 123 LEU B CD1 1 
ATOM   4938 C  CD2 . LEU B 1 123 ? 108.719 117.189 152.325 1.00 40.79  ? 123 LEU B CD2 1 
ATOM   4939 N  N   . THR B 1 124 ? 112.227 117.906 155.478 1.00 35.82  ? 124 THR B N   1 
ATOM   4940 C  CA  . THR B 1 124 ? 113.464 118.627 155.198 1.00 35.82  ? 124 THR B CA  1 
ATOM   4941 C  C   . THR B 1 124 ? 114.661 117.927 155.828 1.00 35.82  ? 124 THR B C   1 
ATOM   4942 O  O   . THR B 1 124 ? 115.731 117.832 155.214 1.00 35.82  ? 124 THR B O   1 
ATOM   4943 C  CB  . THR B 1 124 ? 113.349 120.069 155.695 1.00 35.82  ? 124 THR B CB  1 
ATOM   4944 O  OG1 . THR B 1 124 ? 112.493 120.808 154.816 1.00 35.82  ? 124 THR B OG1 1 
ATOM   4945 C  CG2 . THR B 1 124 ? 114.711 120.739 155.741 1.00 35.82  ? 124 THR B CG2 1 
ATOM   4946 N  N   . LEU B 1 125 ? 114.499 117.426 157.055 1.00 33.15  ? 125 LEU B N   1 
ATOM   4947 C  CA  . LEU B 1 125 ? 115.588 116.700 157.701 1.00 33.15  ? 125 LEU B CA  1 
ATOM   4948 C  C   . LEU B 1 125 ? 115.958 115.450 156.915 1.00 33.15  ? 125 LEU B C   1 
ATOM   4949 O  O   . LEU B 1 125 ? 117.143 115.143 156.746 1.00 33.15  ? 125 LEU B O   1 
ATOM   4950 C  CB  . LEU B 1 125 ? 115.199 116.338 159.134 1.00 33.15  ? 125 LEU B CB  1 
ATOM   4951 C  CG  . LEU B 1 125 ? 116.273 115.670 159.992 1.00 33.15  ? 125 LEU B CG  1 
ATOM   4952 C  CD1 . LEU B 1 125 ? 117.599 116.405 159.879 1.00 33.15  ? 125 LEU B CD1 1 
ATOM   4953 C  CD2 . LEU B 1 125 ? 115.817 115.602 161.438 1.00 33.15  ? 125 LEU B CD2 1 
ATOM   4954 N  N   . GLY B 1 126 ? 114.959 114.715 156.426 1.00 33.60  ? 126 GLY B N   1 
ATOM   4955 C  CA  . GLY B 1 126 ? 115.239 113.536 155.628 1.00 33.60  ? 126 GLY B CA  1 
ATOM   4956 C  C   . GLY B 1 126 ? 115.916 113.871 154.314 1.00 33.60  ? 126 GLY B C   1 
ATOM   4957 O  O   . GLY B 1 126 ? 116.851 113.184 153.899 1.00 33.60  ? 126 GLY B O   1 
ATOM   4958 N  N   . PHE B 1 127 ? 115.454 114.930 153.643 1.00 33.98  ? 127 PHE B N   1 
ATOM   4959 C  CA  . PHE B 1 127 ? 116.113 115.372 152.418 1.00 33.98  ? 127 PHE B CA  1 
ATOM   4960 C  C   . PHE B 1 127 ? 117.575 115.706 152.675 1.00 33.98  ? 127 PHE B C   1 
ATOM   4961 O  O   . PHE B 1 127 ? 118.466 115.249 151.948 1.00 33.98  ? 127 PHE B O   1 
ATOM   4962 C  CB  . PHE B 1 127 ? 115.390 116.586 151.836 1.00 33.98  ? 127 PHE B CB  1 
ATOM   4963 C  CG  . PHE B 1 127 ? 114.126 116.249 151.107 1.00 33.98  ? 127 PHE B CG  1 
ATOM   4964 C  CD1 . PHE B 1 127 ? 113.986 115.031 150.466 1.00 33.98  ? 127 PHE B CD1 1 
ATOM   4965 C  CD2 . PHE B 1 127 ? 113.083 117.155 151.052 1.00 33.98  ? 127 PHE B CD2 1 
ATOM   4966 C  CE1 . PHE B 1 127 ? 112.827 114.721 149.787 1.00 33.98  ? 127 PHE B CE1 1 
ATOM   4967 C  CE2 . PHE B 1 127 ? 111.920 116.849 150.376 1.00 33.98  ? 127 PHE B CE2 1 
ATOM   4968 C  CZ  . PHE B 1 127 ? 111.792 115.630 149.743 1.00 33.98  ? 127 PHE B CZ  1 
ATOM   4969 N  N   . MET B 1 128 ? 117.841 116.498 153.715 1.00 29.03  ? 128 MET B N   1 
ATOM   4970 C  CA  . MET B 1 128 ? 119.212 116.898 154.011 1.00 29.03  ? 128 MET B CA  1 
ATOM   4971 C  C   . MET B 1 128 ? 120.075 115.692 154.353 1.00 29.03  ? 128 MET B C   1 
ATOM   4972 O  O   . MET B 1 128 ? 121.192 115.556 153.847 1.00 29.03  ? 128 MET B O   1 
ATOM   4973 C  CB  . MET B 1 128 ? 119.231 117.914 155.151 1.00 29.03  ? 128 MET B CB  1 
ATOM   4974 C  CG  . MET B 1 128 ? 118.688 119.274 154.764 1.00 29.03  ? 128 MET B CG  1 
ATOM   4975 S  SD  . MET B 1 128 ? 119.038 120.558 155.976 1.00 29.03  ? 128 MET B SD  1 
ATOM   4976 C  CE  . MET B 1 128 ? 120.751 120.915 155.608 1.00 29.03  ? 128 MET B CE  1 
ATOM   4977 N  N   . SER B 1 129 ? 119.565 114.792 155.195 1.00 28.32  ? 129 SER B N   1 
ATOM   4978 C  CA  . SER B 1 129 ? 120.351 113.633 155.604 1.00 28.32  ? 129 SER B CA  1 
ATOM   4979 C  C   . SER B 1 129 ? 120.637 112.713 154.424 1.00 28.32  ? 129 SER B C   1 
ATOM   4980 O  O   . SER B 1 129 ? 121.768 112.248 154.248 1.00 28.32  ? 129 SER B O   1 
ATOM   4981 C  CB  . SER B 1 129 ? 119.627 112.877 156.715 1.00 28.32  ? 129 SER B CB  1 
ATOM   4982 O  OG  . SER B 1 129 ? 119.669 113.602 157.929 1.00 28.32  ? 129 SER B OG  1 
ATOM   4983 N  N   . SER B 1 130 ? 119.623 112.440 153.599 1.00 28.44  ? 130 SER B N   1 
ATOM   4984 C  CA  . SER B 1 130 ? 119.819 111.550 152.460 1.00 28.44  ? 130 SER B CA  1 
ATOM   4985 C  C   . SER B 1 130 ? 120.775 112.152 151.440 1.00 28.44  ? 130 SER B C   1 
ATOM   4986 O  O   . SER B 1 130 ? 121.675 111.462 150.949 1.00 28.44  ? 130 SER B O   1 
ATOM   4987 C  CB  . SER B 1 130 ? 118.475 111.228 151.811 1.00 28.44  ? 130 SER B CB  1 
ATOM   4988 O  OG  . SER B 1 130 ? 117.901 112.386 151.235 1.00 28.44  ? 130 SER B OG  1 
ATOM   4989 N  N   . THR B 1 131 ? 120.600 113.436 151.108 1.00 24.44  ? 131 THR B N   1 
ATOM   4990 C  CA  . THR B 1 131 ? 121.501 114.076 150.156 1.00 24.44  ? 131 THR B CA  1 
ATOM   4991 C  C   . THR B 1 131 ? 122.922 114.126 150.697 1.00 24.44  ? 131 THR B C   1 
ATOM   4992 O  O   . THR B 1 131 ? 123.885 113.888 149.960 1.00 24.44  ? 131 THR B O   1 
ATOM   4993 C  CB  . THR B 1 131 ? 121.005 115.483 149.827 1.00 24.44  ? 131 THR B CB  1 
ATOM   4994 O  OG1 . THR B 1 131 ? 119.657 115.414 149.349 1.00 24.44  ? 131 THR B OG1 1 
ATOM   4995 C  CG2 . THR B 1 131 ? 121.876 116.115 148.758 1.00 24.44  ? 131 THR B CG2 1 
ATOM   4996 N  N   . ALA B 1 132 ? 123.073 114.426 151.988 1.00 26.38  ? 132 ALA B N   1 
ATOM   4997 C  CA  . ALA B 1 132 ? 124.395 114.499 152.592 1.00 26.38  ? 132 ALA B CA  1 
ATOM   4998 C  C   . ALA B 1 132 ? 125.081 113.139 152.601 1.00 26.38  ? 132 ALA B C   1 
ATOM   4999 O  O   . ALA B 1 132 ? 126.281 113.041 152.323 1.00 26.38  ? 132 ALA B O   1 
ATOM   5000 C  CB  . ALA B 1 132 ? 124.272 115.057 154.006 1.00 26.38  ? 132 ALA B CB  1 
ATOM   5001 N  N   . PHE B 1 133 ? 124.340 112.078 152.930 1.00 26.97  ? 133 PHE B N   1 
ATOM   5002 C  CA  . PHE B 1 133 ? 124.931 110.744 152.921 1.00 26.97  ? 133 PHE B CA  1 
ATOM   5003 C  C   . PHE B 1 133 ? 125.290 110.304 151.509 1.00 26.97  ? 133 PHE B C   1 
ATOM   5004 O  O   . PHE B 1 133 ? 126.362 109.732 151.285 1.00 26.97  ? 133 PHE B O   1 
ATOM   5005 C  CB  . PHE B 1 133 ? 123.982 109.734 153.559 1.00 26.97  ? 133 PHE B CB  1 
ATOM   5006 C  CG  . PHE B 1 133 ? 124.527 108.336 153.591 1.00 26.97  ? 133 PHE B CG  1 
ATOM   5007 C  CD1 . PHE B 1 133 ? 125.436 107.954 154.560 1.00 26.97  ? 133 PHE B CD1 1 
ATOM   5008 C  CD2 . PHE B 1 133 ? 124.137 107.405 152.642 1.00 26.97  ? 133 PHE B CD2 1 
ATOM   5009 C  CE1 . PHE B 1 133 ? 125.941 106.671 154.589 1.00 26.97  ? 133 PHE B CE1 1 
ATOM   5010 C  CE2 . PHE B 1 133 ? 124.639 106.122 152.665 1.00 26.97  ? 133 PHE B CE2 1 
ATOM   5011 C  CZ  . PHE B 1 133 ? 125.542 105.754 153.640 1.00 26.97  ? 133 PHE B CZ  1 
ATOM   5012 N  N   . LEU B 1 134 ? 124.404 110.551 150.543 1.00 25.33  ? 134 LEU B N   1 
ATOM   5013 C  CA  . LEU B 1 134 ? 124.674 110.099 149.185 1.00 25.33  ? 134 LEU B CA  1 
ATOM   5014 C  C   . LEU B 1 134 ? 125.808 110.896 148.556 1.00 25.33  ? 134 LEU B C   1 
ATOM   5015 O  O   . LEU B 1 134 ? 126.545 110.368 147.717 1.00 25.33  ? 134 LEU B O   1 
ATOM   5016 C  CB  . LEU B 1 134 ? 123.405 110.195 148.340 1.00 25.33  ? 134 LEU B CB  1 
ATOM   5017 C  CG  . LEU B 1 134 ? 123.561 109.945 146.843 1.00 25.33  ? 134 LEU B CG  1 
ATOM   5018 C  CD1 . LEU B 1 134 ? 123.788 108.465 146.599 1.00 25.33  ? 134 LEU B CD1 1 
ATOM   5019 C  CD2 . LEU B 1 134 ? 122.344 110.424 146.090 1.00 25.33  ? 134 LEU B CD2 1 
ATOM   5020 N  N   . SER B 1 135 ? 125.978 112.154 148.961 1.00 25.70  ? 135 SER B N   1 
ATOM   5021 C  CA  . SER B 1 135 ? 127.061 112.980 148.449 1.00 25.70  ? 135 SER B CA  1 
ATOM   5022 C  C   . SER B 1 135 ? 128.396 112.674 149.111 1.00 25.70  ? 135 SER B C   1 
ATOM   5023 O  O   . SER B 1 135 ? 129.413 113.247 148.707 1.00 25.70  ? 135 SER B O   1 
ATOM   5024 C  CB  . SER B 1 135 ? 126.721 114.459 148.627 1.00 25.70  ? 135 SER B CB  1 
ATOM   5025 O  OG  . SER B 1 135 ? 127.765 115.278 148.138 1.00 25.70  ? 135 SER B OG  1 
ATOM   5026 N  N   . MET B 1 136 ? 128.414 111.793 150.115 1.00 27.40  ? 136 MET B N   1 
ATOM   5027 C  CA  . MET B 1 136 ? 129.672 111.378 150.724 1.00 27.40  ? 136 MET B CA  1 
ATOM   5028 C  C   . MET B 1 136 ? 130.592 110.723 149.705 1.00 27.40  ? 136 MET B C   1 
ATOM   5029 O  O   . MET B 1 136 ? 131.818 110.777 149.848 1.00 27.40  ? 136 MET B O   1 
ATOM   5030 C  CB  . MET B 1 136 ? 129.407 110.392 151.862 1.00 27.40  ? 136 MET B CB  1 
ATOM   5031 C  CG  . MET B 1 136 ? 130.403 110.448 153.000 1.00 27.40  ? 136 MET B CG  1 
ATOM   5032 S  SD  . MET B 1 136 ? 129.832 109.576 154.473 1.00 27.40  ? 136 MET B SD  1 
ATOM   5033 C  CE  . MET B 1 136 ? 128.218 110.295 154.722 1.00 27.40  ? 136 MET B CE  1 
ATOM   5034 N  N   . TRP B 1 137 ? 130.021 110.099 148.676 1.00 26.56  ? 137 TRP B N   1 
ATOM   5035 C  CA  . TRP B 1 137 ? 130.742 109.201 147.785 1.00 26.56  ? 137 TRP B CA  1 
ATOM   5036 C  C   . TRP B 1 137 ? 130.831 109.707 146.354 1.00 26.56  ? 137 TRP B C   1 
ATOM   5037 O  O   . TRP B 1 137 ? 131.906 109.653 145.749 1.00 26.56  ? 137 TRP B O   1 
ATOM   5038 C  CB  . TRP B 1 137 ? 130.072 107.820 147.801 1.00 26.56  ? 137 TRP B CB  1 
ATOM   5039 C  CG  . TRP B 1 137 ? 129.673 107.373 149.172 1.00 26.56  ? 137 TRP B CG  1 
ATOM   5040 C  CD1 . TRP B 1 137 ? 128.406 107.295 149.670 1.00 26.56  ? 137 TRP B CD1 1 
ATOM   5041 C  CD2 . TRP B 1 137 ? 130.544 106.944 150.224 1.00 26.56  ? 137 TRP B CD2 1 
ATOM   5042 N  NE1 . TRP B 1 137 ? 128.434 106.847 150.966 1.00 26.56  ? 137 TRP B NE1 1 
ATOM   5043 C  CE2 . TRP B 1 137 ? 129.735 106.623 151.330 1.00 26.56  ? 137 TRP B CE2 1 
ATOM   5044 C  CE3 . TRP B 1 137 ? 131.930 106.800 150.337 1.00 26.56  ? 137 TRP B CE3 1 
ATOM   5045 C  CZ2 . TRP B 1 137 ? 130.265 106.167 152.534 1.00 26.56  ? 137 TRP B CZ2 1 
ATOM   5046 C  CZ3 . TRP B 1 137 ? 132.453 106.348 151.533 1.00 26.56  ? 137 TRP B CZ3 1 
ATOM   5047 C  CH2 . TRP B 1 137 ? 131.623 106.036 152.615 1.00 26.56  ? 137 TRP B CH2 1 
ATOM   5048 N  N   . LEU B 1 138 ? 129.728 110.195 145.785 1.00 25.42  ? 138 LEU B N   1 
ATOM   5049 C  CA  . LEU B 1 138 ? 129.712 110.483 144.351 1.00 25.42  ? 138 LEU B CA  1 
ATOM   5050 C  C   . LEU B 1 138 ? 130.360 111.828 144.038 1.00 25.42  ? 138 LEU B C   1 
ATOM   5051 O  O   . LEU B 1 138 ? 131.452 111.885 143.463 1.00 25.42  ? 138 LEU B O   1 
ATOM   5052 C  CB  . LEU B 1 138 ? 128.269 110.453 143.836 1.00 25.42  ? 138 LEU B CB  1 
ATOM   5053 C  CG  . LEU B 1 138 ? 127.568 109.104 143.683 1.00 25.42  ? 138 LEU B CG  1 
ATOM   5054 C  CD1 . LEU B 1 138 ? 126.986 108.646 145.001 1.00 25.42  ? 138 LEU B CD1 1 
ATOM   5055 C  CD2 . LEU B 1 138 ? 126.477 109.203 142.636 1.00 25.42  ? 138 LEU B CD2 1 
ATOM   5056 N  N   . SER B 1 139 ? 129.707 112.917 144.435 1.00 29.55  ? 139 SER B N   1 
ATOM   5057 C  CA  . SER B 1 139 ? 130.166 114.287 144.235 1.00 29.55  ? 139 SER B CA  1 
ATOM   5058 C  C   . SER B 1 139 ? 129.083 115.203 144.787 1.00 29.55  ? 139 SER B C   1 
ATOM   5059 O  O   . SER B 1 139 ? 127.963 114.767 145.067 1.00 29.55  ? 139 SER B O   1 
ATOM   5060 C  CB  . SER B 1 139 ? 130.443 114.623 142.769 1.00 29.55  ? 139 SER B CB  1 
ATOM   5061 O  OG  . SER B 1 139 ? 131.623 113.987 142.315 1.00 29.55  ? 139 SER B OG  1 
ATOM   5062 N  N   . ASN B 1 140 ? 129.425 116.482 144.935 1.00 29.40  ? 140 ASN B N   1 
ATOM   5063 C  CA  . ASN B 1 140 ? 128.399 117.469 145.247 1.00 29.40  ? 140 ASN B CA  1 
ATOM   5064 C  C   . ASN B 1 140 ? 127.489 117.705 144.049 1.00 29.40  ? 140 ASN B C   1 
ATOM   5065 O  O   . ASN B 1 140 ? 126.259 117.671 144.172 1.00 29.40  ? 140 ASN B O   1 
ATOM   5066 C  CB  . ASN B 1 140 ? 129.045 118.778 145.696 1.00 29.40  ? 140 ASN B CB  1 
ATOM   5067 C  CG  . ASN B 1 140 ? 129.385 118.784 147.166 1.00 29.40  ? 140 ASN B CG  1 
ATOM   5068 O  OD1 . ASN B 1 140 ? 128.694 118.167 147.975 1.00 29.40  ? 140 ASN B OD1 1 
ATOM   5069 N  ND2 . ASN B 1 140 ? 130.437 119.503 147.527 1.00 29.40  ? 140 ASN B ND2 1 
ATOM   5070 N  N   . THR B 1 141 ? 128.083 117.926 142.876 1.00 27.45  ? 141 THR B N   1 
ATOM   5071 C  CA  . THR B 1 141 ? 127.306 118.271 141.691 1.00 27.45  ? 141 THR B CA  1 
ATOM   5072 C  C   . THR B 1 141 ? 126.398 117.123 141.270 1.00 27.45  ? 141 THR B C   1 
ATOM   5073 O  O   . THR B 1 141 ? 125.210 117.326 140.992 1.00 27.45  ? 141 THR B O   1 
ATOM   5074 C  CB  . THR B 1 141 ? 128.248 118.658 140.552 1.00 27.45  ? 141 THR B CB  1 
ATOM   5075 O  OG1 . THR B 1 141 ? 129.159 119.666 141.006 1.00 27.45  ? 141 THR B OG1 1 
ATOM   5076 C  CG2 . THR B 1 141 ? 127.467 119.195 139.373 1.00 27.45  ? 141 THR B CG2 1 
ATOM   5077 N  N   . SER B 1 142 ? 126.939 115.904 141.236 1.00 25.29  ? 142 SER B N   1 
ATOM   5078 C  CA  . SER B 1 142 ? 126.172 114.757 140.760 1.00 25.29  ? 142 SER B CA  1 
ATOM   5079 C  C   . SER B 1 142 ? 124.967 114.488 141.652 1.00 25.29  ? 142 SER B C   1 
ATOM   5080 O  O   . SER B 1 142 ? 123.843 114.320 141.166 1.00 25.29  ? 142 SER B O   1 
ATOM   5081 C  CB  . SER B 1 142 ? 127.076 113.528 140.692 1.00 25.29  ? 142 SER B CB  1 
ATOM   5082 O  OG  . SER B 1 142 ? 128.206 113.775 139.875 1.00 25.29  ? 142 SER B OG  1 
ATOM   5083 N  N   . THR B 1 143 ? 125.184 114.444 142.968 1.00 24.67  ? 143 THR B N   1 
ATOM   5084 C  CA  . THR B 1 143 ? 124.084 114.166 143.885 1.00 24.67  ? 143 THR B CA  1 
ATOM   5085 C  C   . THR B 1 143 ? 123.080 115.310 143.914 1.00 24.67  ? 143 THR B C   1 
ATOM   5086 O  O   . THR B 1 143 ? 121.866 115.074 143.946 1.00 24.67  ? 143 THR B O   1 
ATOM   5087 C  CB  . THR B 1 143 ? 124.621 113.887 145.286 1.00 24.67  ? 143 THR B CB  1 
ATOM   5088 O  OG1 . THR B 1 143 ? 125.320 115.038 145.770 1.00 24.67  ? 143 THR B OG1 1 
ATOM   5089 C  CG2 . THR B 1 143 ? 125.562 112.698 145.251 1.00 24.67  ? 143 THR B CG2 1 
ATOM   5090 N  N   . ALA B 1 144 ? 123.562 116.555 143.906 1.00 24.77  ? 144 ALA B N   1 
ATOM   5091 C  CA  . ALA B 1 144 ? 122.646 117.688 143.865 1.00 24.77  ? 144 ALA B CA  1 
ATOM   5092 C  C   . ALA B 1 144 ? 121.795 117.666 142.605 1.00 24.77  ? 144 ALA B C   1 
ATOM   5093 O  O   . ALA B 1 144 ? 120.640 118.103 142.628 1.00 24.77  ? 144 ALA B O   1 
ATOM   5094 C  CB  . ALA B 1 144 ? 123.423 119.000 143.958 1.00 24.77  ? 144 ALA B CB  1 
ATOM   5095 N  N   . ALA B 1 145 ? 122.345 117.165 141.499 1.00 25.79  ? 145 ALA B N   1 
ATOM   5096 C  CA  . ALA B 1 145 ? 121.571 117.067 140.269 1.00 25.79  ? 145 ALA B CA  1 
ATOM   5097 C  C   . ALA B 1 145 ? 120.597 115.897 140.285 1.00 25.79  ? 145 ALA B C   1 
ATOM   5098 O  O   . ALA B 1 145 ? 119.498 116.011 139.733 1.00 25.79  ? 145 ALA B O   1 
ATOM   5099 C  CB  . ALA B 1 145 ? 122.510 116.946 139.071 1.00 25.79  ? 145 ALA B CB  1 
ATOM   5100 N  N   . MET B 1 146 ? 120.971 114.772 140.899 1.00 27.29  ? 146 MET B N   1 
ATOM   5101 C  CA  . MET B 1 146 ? 120.124 113.587 140.793 1.00 27.29  ? 146 MET B CA  1 
ATOM   5102 C  C   . MET B 1 146 ? 119.011 113.568 141.838 1.00 27.29  ? 146 MET B C   1 
ATOM   5103 O  O   . MET B 1 146 ? 117.907 113.094 141.549 1.00 27.29  ? 146 MET B O   1 
ATOM   5104 C  CB  . MET B 1 146 ? 120.964 112.312 140.890 1.00 27.29  ? 146 MET B CB  1 
ATOM   5105 C  CG  . MET B 1 146 ? 121.695 112.121 142.202 1.00 27.29  ? 146 MET B CG  1 
ATOM   5106 S  SD  . MET B 1 146 ? 122.286 110.432 142.415 1.00 27.29  ? 146 MET B SD  1 
ATOM   5107 C  CE  . MET B 1 146 ? 122.762 110.026 140.739 1.00 27.29  ? 146 MET B CE  1 
ATOM   5108 N  N   . VAL B 1 147 ? 119.262 114.068 143.050 1.00 26.74  ? 147 VAL B N   1 
ATOM   5109 C  CA  . VAL B 1 147 ? 118.233 114.009 144.086 1.00 26.74  ? 147 VAL B CA  1 
ATOM   5110 C  C   . VAL B 1 147 ? 117.274 115.192 144.043 1.00 26.74  ? 147 VAL B C   1 
ATOM   5111 O  O   . VAL B 1 147 ? 116.206 115.130 144.668 1.00 26.74  ? 147 VAL B O   1 
ATOM   5112 C  CB  . VAL B 1 147 ? 118.842 113.924 145.496 1.00 26.74  ? 147 VAL B CB  1 
ATOM   5113 C  CG1 . VAL B 1 147 ? 119.901 112.855 145.546 1.00 26.74  ? 147 VAL B CG1 1 
ATOM   5114 C  CG2 . VAL B 1 147 ? 119.404 115.266 145.920 1.00 26.74  ? 147 VAL B CG2 1 
ATOM   5115 N  N   . MET B 1 148 ? 117.626 116.268 143.346 1.00 31.22  ? 148 MET B N   1 
ATOM   5116 C  CA  . MET B 1 148 ? 116.740 117.426 143.294 1.00 31.22  ? 148 MET B CA  1 
ATOM   5117 C  C   . MET B 1 148 ? 115.402 117.141 142.619 1.00 31.22  ? 148 MET B C   1 
ATOM   5118 O  O   . MET B 1 148 ? 114.376 117.615 143.138 1.00 31.22  ? 148 MET B O   1 
ATOM   5119 C  CB  . MET B 1 148 ? 117.456 118.600 142.619 1.00 31.22  ? 148 MET B CB  1 
ATOM   5120 C  CG  . MET B 1 148 ? 116.615 119.853 142.559 1.00 31.22  ? 148 MET B CG  1 
ATOM   5121 S  SD  . MET B 1 148 ? 116.263 120.522 144.193 1.00 31.22  ? 148 MET B SD  1 
ATOM   5122 C  CE  . MET B 1 148 ? 114.707 121.347 143.883 1.00 31.22  ? 148 MET B CE  1 
ATOM   5123 N  N   . PRO B 1 149 ? 115.325 116.431 141.482 1.00 28.76  ? 149 PRO B N   1 
ATOM   5124 C  CA  . PRO B 1 149 ? 113.997 116.147 140.910 1.00 28.76  ? 149 PRO B CA  1 
ATOM   5125 C  C   . PRO B 1 149 ? 113.082 115.391 141.855 1.00 28.76  ? 149 PRO B C   1 
ATOM   5126 O  O   . PRO B 1 149 ? 111.874 115.654 141.883 1.00 28.76  ? 149 PRO B O   1 
ATOM   5127 C  CB  . PRO B 1 149 ? 114.325 115.322 139.658 1.00 28.76  ? 149 PRO B CB  1 
ATOM   5128 C  CG  . PRO B 1 149 ? 115.703 115.705 139.304 1.00 28.76  ? 149 PRO B CG  1 
ATOM   5129 C  CD  . PRO B 1 149 ? 116.402 115.939 140.604 1.00 28.76  ? 149 PRO B CD  1 
ATOM   5130 N  N   . ILE B 1 150 ? 113.627 114.462 142.642 1.00 29.90  ? 150 ILE B N   1 
ATOM   5131 C  CA  . ILE B 1 150 ? 112.805 113.710 143.586 1.00 29.90  ? 150 ILE B CA  1 
ATOM   5132 C  C   . ILE B 1 150 ? 112.232 114.635 144.651 1.00 29.90  ? 150 ILE B C   1 
ATOM   5133 O  O   . ILE B 1 150 ? 111.048 114.549 145.000 1.00 29.90  ? 150 ILE B O   1 
ATOM   5134 C  CB  . ILE B 1 150 ? 113.623 112.566 144.211 1.00 29.90  ? 150 ILE B CB  1 
ATOM   5135 C  CG1 . ILE B 1 150 ? 114.386 111.801 143.129 1.00 29.90  ? 150 ILE B CG1 1 
ATOM   5136 C  CG2 . ILE B 1 150 ? 112.718 111.636 144.994 1.00 29.90  ? 150 ILE B CG2 1 
ATOM   5137 C  CD1 . ILE B 1 150 ? 113.500 111.205 142.060 1.00 29.90  ? 150 ILE B CD1 1 
ATOM   5138 N  N   . ALA B 1 151 ? 113.063 115.531 145.190 1.00 31.04  ? 151 ALA B N   1 
ATOM   5139 C  CA  . ALA B 1 151 ? 112.586 116.471 146.199 1.00 31.04  ? 151 ALA B CA  1 
ATOM   5140 C  C   . ALA B 1 151 ? 111.546 117.421 145.621 1.00 31.04  ? 151 ALA B C   1 
ATOM   5141 O  O   . ALA B 1 151 ? 110.543 117.735 146.277 1.00 31.04  ? 151 ALA B O   1 
ATOM   5142 C  CB  . ALA B 1 151 ? 113.762 117.249 146.785 1.00 31.04  ? 151 ALA B CB  1 
ATOM   5143 N  N   . GLU B 1 152 ? 111.769 117.894 144.394 1.00 34.21  ? 152 GLU B N   1 
ATOM   5144 C  CA  . GLU B 1 152 ? 110.789 118.762 143.752 1.00 34.21  ? 152 GLU B CA  1 
ATOM   5145 C  C   . GLU B 1 152 ? 109.467 118.037 143.552 1.00 34.21  ? 152 GLU B C   1 
ATOM   5146 O  O   . GLU B 1 152 ? 108.395 118.616 143.759 1.00 34.21  ? 152 GLU B O   1 
ATOM   5147 C  CB  . GLU B 1 152 ? 111.332 119.273 142.418 1.00 34.21  ? 152 GLU B CB  1 
ATOM   5148 C  CG  . GLU B 1 152 ? 110.381 120.197 141.676 1.00 34.21  ? 152 GLU B CG  1 
ATOM   5149 C  CD  . GLU B 1 152 ? 110.522 121.646 142.099 1.00 34.21  ? 152 GLU B CD  1 
ATOM   5150 O  OE1 . GLU B 1 152 ? 111.226 121.911 143.097 1.00 34.21  ? 152 GLU B OE1 1 
ATOM   5151 O  OE2 . GLU B 1 152 ? 109.927 122.520 141.435 1.00 34.21  ? 152 GLU B OE2 1 
ATOM   5152 N  N   . ALA B 1 153 ? 109.525 116.764 143.152 1.00 31.61  ? 153 ALA B N   1 
ATOM   5153 C  CA  . ALA B 1 153 ? 108.307 115.976 143.005 1.00 31.61  ? 153 ALA B CA  1 
ATOM   5154 C  C   . ALA B 1 153 ? 107.595 115.802 144.339 1.00 31.61  ? 153 ALA B C   1 
ATOM   5155 O  O   . ALA B 1 153 ? 106.364 115.885 144.405 1.00 31.61  ? 153 ALA B O   1 
ATOM   5156 C  CB  . ALA B 1 153 ? 108.636 114.617 142.392 1.00 31.61  ? 153 ALA B CB  1 
ATOM   5157 N  N   . VAL B 1 154 ? 108.351 115.558 145.412 1.00 32.28  ? 154 VAL B N   1 
ATOM   5158 C  CA  . VAL B 1 154 ? 107.743 115.409 146.734 1.00 32.28  ? 154 VAL B CA  1 
ATOM   5159 C  C   . VAL B 1 154 ? 107.014 116.688 147.128 1.00 32.28  ? 154 VAL B C   1 
ATOM   5160 O  O   . VAL B 1 154 ? 105.863 116.658 147.583 1.00 32.28  ? 154 VAL B O   1 
ATOM   5161 C  CB  . VAL B 1 154 ? 108.809 115.033 147.779 1.00 32.28  ? 154 VAL B CB  1 
ATOM   5162 C  CG1 . VAL B 1 154 ? 108.237 115.149 149.180 1.00 32.28  ? 154 VAL B CG1 1 
ATOM   5163 C  CG2 . VAL B 1 154 ? 109.331 113.630 147.537 1.00 32.28  ? 154 VAL B CG2 1 
ATOM   5164 N  N   . VAL B 1 155 ? 107.677 117.831 146.948 1.00 34.82  ? 155 VAL B N   1 
ATOM   5165 C  CA  . VAL B 1 155 ? 107.074 119.106 147.327 1.00 34.82  ? 155 VAL B CA  1 
ATOM   5166 C  C   . VAL B 1 155 ? 105.838 119.386 146.482 1.00 34.82  ? 155 VAL B C   1 
ATOM   5167 O  O   . VAL B 1 155 ? 104.805 119.836 146.996 1.00 34.82  ? 155 VAL B O   1 
ATOM   5168 C  CB  . VAL B 1 155 ? 108.110 120.239 147.217 1.00 34.82  ? 155 VAL B CB  1 
ATOM   5169 C  CG1 . VAL B 1 155 ? 107.459 121.580 147.486 1.00 34.82  ? 155 VAL B CG1 1 
ATOM   5170 C  CG2 . VAL B 1 155 ? 109.248 120.000 148.190 1.00 34.82  ? 155 VAL B CG2 1 
ATOM   5171 N  N   . GLN B 1 156 ? 105.918 119.120 145.176 1.00 38.51  ? 156 GLN B N   1 
ATOM   5172 C  CA  . GLN B 1 156 ? 104.773 119.347 144.302 1.00 38.51  ? 156 GLN B CA  1 
ATOM   5173 C  C   . GLN B 1 156 ? 103.596 118.460 144.686 1.00 38.51  ? 156 GLN B C   1 
ATOM   5174 O  O   . GLN B 1 156 ? 102.445 118.911 144.688 1.00 38.51  ? 156 GLN B O   1 
ATOM   5175 C  CB  . GLN B 1 156 ? 105.171 119.107 142.846 1.00 38.51  ? 156 GLN B CB  1 
ATOM   5176 C  CG  . GLN B 1 156 ? 104.276 119.801 141.837 1.00 38.51  ? 156 GLN B CG  1 
ATOM   5177 C  CD  . GLN B 1 156 ? 103.949 121.226 142.230 1.00 38.51  ? 156 GLN B CD  1 
ATOM   5178 O  OE1 . GLN B 1 156 ? 104.841 122.061 142.379 1.00 38.51  ? 156 GLN B OE1 1 
ATOM   5179 N  NE2 . GLN B 1 156 ? 102.664 121.513 142.399 1.00 38.51  ? 156 GLN B NE2 1 
ATOM   5180 N  N   . GLN B 1 157 ? 103.862 117.193 145.013 1.00 36.62  ? 157 GLN B N   1 
ATOM   5181 C  CA  . GLN B 1 157 ? 102.779 116.292 145.388 1.00 36.62  ? 157 GLN B CA  1 
ATOM   5182 C  C   . GLN B 1 157 ? 102.140 116.711 146.703 1.00 36.62  ? 157 GLN B C   1 
ATOM   5183 O  O   . GLN B 1 157 ? 100.915 116.640 146.852 1.00 36.62  ? 157 GLN B O   1 
ATOM   5184 C  CB  . GLN B 1 157 ? 103.290 114.854 145.469 1.00 36.62  ? 157 GLN B CB  1 
ATOM   5185 C  CG  . GLN B 1 157 ? 103.693 114.272 144.126 1.00 36.62  ? 157 GLN B CG  1 
ATOM   5186 C  CD  . GLN B 1 157 ? 102.592 114.370 143.089 1.00 36.62  ? 157 GLN B CD  1 
ATOM   5187 O  OE1 . GLN B 1 157 ? 102.845 114.703 141.932 1.00 36.62  ? 157 GLN B OE1 1 
ATOM   5188 N  NE2 . GLN B 1 157 ? 101.364 114.068 143.494 1.00 36.62  ? 157 GLN B NE2 1 
ATOM   5189 N  N   . ILE B 1 158 ? 102.947 117.154 147.670 1.00 37.14  ? 158 ILE B N   1 
ATOM   5190 C  CA  . ILE B 1 158 ? 102.378 117.627 148.930 1.00 37.14  ? 158 ILE B CA  1 
ATOM   5191 C  C   . ILE B 1 158 ? 101.536 118.876 148.702 1.00 37.14  ? 158 ILE B C   1 
ATOM   5192 O  O   . ILE B 1 158 ? 100.448 119.021 149.272 1.00 37.14  ? 158 ILE B O   1 
ATOM   5193 C  CB  . ILE B 1 158 ? 103.486 117.864 149.970 1.00 37.14  ? 158 ILE B CB  1 
ATOM   5194 C  CG1 . ILE B 1 158 ? 104.187 116.547 150.292 1.00 37.14  ? 158 ILE B CG1 1 
ATOM   5195 C  CG2 . ILE B 1 158 ? 102.913 118.479 151.232 1.00 37.14  ? 158 ILE B CG2 1 
ATOM   5196 C  CD1 . ILE B 1 158 ? 105.438 116.714 151.096 1.00 37.14  ? 158 ILE B CD1 1 
ATOM   5197 N  N   . ILE B 1 159 ? 102.017 119.793 147.859 1.00 39.83  ? 159 ILE B N   1 
ATOM   5198 C  CA  . ILE B 1 159 ? 101.241 120.993 147.552 1.00 39.83  ? 159 ILE B CA  1 
ATOM   5199 C  C   . ILE B 1 159 ? 99.920  120.620 146.891 1.00 39.83  ? 159 ILE B C   1 
ATOM   5200 O  O   . ILE B 1 159 ? 98.864  121.171 147.224 1.00 39.83  ? 159 ILE B O   1 
ATOM   5201 C  CB  . ILE B 1 159 ? 102.067 121.952 146.675 1.00 39.83  ? 159 ILE B CB  1 
ATOM   5202 C  CG1 . ILE B 1 159 ? 103.108 122.682 147.522 1.00 39.83  ? 159 ILE B CG1 1 
ATOM   5203 C  CG2 . ILE B 1 159 ? 101.165 122.947 145.963 1.00 39.83  ? 159 ILE B CG2 1 
ATOM   5204 C  CD1 . ILE B 1 159 ? 104.286 123.184 146.730 1.00 39.83  ? 159 ILE B CD1 1 
ATOM   5205 N  N   . ASN B 1 160 ? 99.956  119.675 145.948 1.00 43.78  ? 160 ASN B N   1 
ATOM   5206 C  CA  . ASN B 1 160 ? 98.733  119.256 145.269 1.00 43.78  ? 160 ASN B CA  1 
ATOM   5207 C  C   . ASN B 1 160 ? 97.756  118.599 146.236 1.00 43.78  ? 160 ASN B C   1 
ATOM   5208 O  O   . ASN B 1 160 ? 96.547  118.846 146.171 1.00 43.78  ? 160 ASN B O   1 
ATOM   5209 C  CB  . ASN B 1 160 ? 99.072  118.305 144.123 1.00 43.78  ? 160 ASN B CB  1 
ATOM   5210 C  CG  . ASN B 1 160 ? 99.679  119.019 142.935 1.00 43.78  ? 160 ASN B CG  1 
ATOM   5211 O  OD1 . ASN B 1 160 ? 99.938  120.220 142.987 1.00 43.78  ? 160 ASN B OD1 1 
ATOM   5212 N  ND2 . ASN B 1 160 ? 99.913  118.282 141.857 1.00 43.78  ? 160 ASN B ND2 1 
ATOM   5213 N  N   . ALA B 1 161 ? 98.259  117.756 147.140 1.00 45.80  ? 161 ALA B N   1 
ATOM   5214 C  CA  . ALA B 1 161 ? 97.396  117.093 148.107 1.00 45.80  ? 161 ALA B CA  1 
ATOM   5215 C  C   . ALA B 1 161 ? 96.918  118.027 149.209 1.00 45.80  ? 161 ALA B C   1 
ATOM   5216 O  O   . ALA B 1 161 ? 95.969  117.682 149.919 1.00 45.80  ? 161 ALA B O   1 
ATOM   5217 C  CB  . ALA B 1 161 ? 98.119  115.898 148.726 1.00 45.80  ? 161 ALA B CB  1 
ATOM   5218 N  N   . GLU B 1 162 ? 97.548  119.192 149.369 1.00 48.42  ? 162 GLU B N   1 
ATOM   5219 C  CA  . GLU B 1 162 ? 97.121  120.137 150.391 1.00 48.42  ? 162 GLU B CA  1 
ATOM   5220 C  C   . GLU B 1 162 ? 95.745  120.730 150.118 1.00 48.42  ? 162 GLU B C   1 
ATOM   5221 O  O   . GLU B 1 162 ? 95.188  121.379 151.010 1.00 48.42  ? 162 GLU B O   1 
ATOM   5222 C  CB  . GLU B 1 162 ? 98.147  121.263 150.527 1.00 48.42  ? 162 GLU B CB  1 
ATOM   5223 N  N   . ALA B 1 163 ? 95.193  120.538 148.917 1.00 55.42  ? 163 ALA B N   1 
ATOM   5224 C  CA  . ALA B 1 163 ? 93.844  121.024 148.641 1.00 55.42  ? 163 ALA B CA  1 
ATOM   5225 C  C   . ALA B 1 163 ? 92.820  120.361 149.554 1.00 55.42  ? 163 ALA B C   1 
ATOM   5226 O  O   . ALA B 1 163 ? 91.941  121.036 150.105 1.00 55.42  ? 163 ALA B O   1 
ATOM   5227 C  CB  . ALA B 1 163 ? 93.491  120.787 147.173 1.00 55.42  ? 163 ALA B CB  1 
ATOM   5228 N  N   . GLU B 1 164 ? 92.924  119.041 149.730 1.00 60.23  ? 164 GLU B N   1 
ATOM   5229 C  CA  . GLU B 1 164 ? 92.058  118.282 150.637 1.00 60.23  ? 164 GLU B CA  1 
ATOM   5230 C  C   . GLU B 1 164 ? 90.580  118.503 150.324 1.00 60.23  ? 164 GLU B C   1 
ATOM   5231 O  O   . GLU B 1 164 ? 89.753  118.651 151.227 1.00 60.23  ? 164 GLU B O   1 
ATOM   5232 C  CB  . GLU B 1 164 ? 92.360  118.620 152.099 1.00 60.23  ? 164 GLU B CB  1 
ATOM   5233 N  N   . VAL B 1 165 ? 90.248  118.523 149.030 1.00 63.62  ? 165 VAL B N   1 
ATOM   5234 C  CA  . VAL B 1 165 ? 88.876  118.732 148.559 1.00 63.62  ? 165 VAL B CA  1 
ATOM   5235 C  C   . VAL B 1 165 ? 88.288  120.028 149.112 1.00 63.62  ? 165 VAL B C   1 
ATOM   5236 O  O   . VAL B 1 165 ? 87.108  120.096 149.465 1.00 63.62  ? 165 VAL B O   1 
ATOM   5237 C  CB  . VAL B 1 165 ? 87.982  117.538 148.901 1.00 63.62  ? 165 VAL B CB  1 
ATOM   5238 N  N   . GLU B 1 166 ? 89.117  121.065 149.184 1.00 62.81  ? 166 GLU B N   1 
ATOM   5239 C  CA  . GLU B 1 166 ? 88.691  122.362 149.696 1.00 62.81  ? 166 GLU B CA  1 
ATOM   5240 C  C   . GLU B 1 166 ? 89.651  123.458 149.249 1.00 62.81  ? 166 GLU B C   1 
ATOM   5241 O  O   . GLU B 1 166 ? 90.745  123.599 149.797 1.00 62.81  ? 166 GLU B O   1 
ATOM   5242 C  CB  . GLU B 1 166 ? 88.591  122.330 151.214 1.00 62.81  ? 166 GLU B CB  1 
ATOM   5243 N  N   . THR B 1 230 ? 99.611  128.983 146.936 1.00 64.24  ? 230 THR B N   1 
ATOM   5244 C  CA  . THR B 1 230 ? 99.593  129.910 148.061 1.00 64.24  ? 230 THR B CA  1 
ATOM   5245 C  C   . THR B 1 230 ? 101.005 130.363 148.418 1.00 64.24  ? 230 THR B C   1 
ATOM   5246 O  O   . THR B 1 230 ? 101.966 130.037 147.722 1.00 64.24  ? 230 THR B O   1 
ATOM   5247 C  CB  . THR B 1 230 ? 98.934  129.279 149.301 1.00 64.24  ? 230 THR B CB  1 
ATOM   5248 O  OG1 . THR B 1 230 ? 98.924  130.227 150.375 1.00 64.24  ? 230 THR B OG1 1 
ATOM   5249 C  CG2 . THR B 1 230 ? 99.693  128.038 149.734 1.00 64.24  ? 230 THR B CG2 1 
ATOM   5250 N  N   . LYS B 1 231 ? 101.121 131.124 149.508 1.00 62.22  ? 231 LYS B N   1 
ATOM   5251 C  CA  . LYS B 1 231 ? 102.431 131.596 149.943 1.00 62.22  ? 231 LYS B CA  1 
ATOM   5252 C  C   . LYS B 1 231 ? 103.256 130.478 150.568 1.00 62.22  ? 231 LYS B C   1 
ATOM   5253 O  O   . LYS B 1 231 ? 104.490 130.541 150.559 1.00 62.22  ? 231 LYS B O   1 
ATOM   5254 C  CB  . LYS B 1 231 ? 102.270 132.756 150.927 1.00 62.22  ? 231 LYS B CB  1 
ATOM   5255 C  CG  . LYS B 1 231 ? 101.529 132.390 152.204 1.00 62.22  ? 231 LYS B CG  1 
ATOM   5256 C  CD  . LYS B 1 231 ? 101.469 133.564 153.169 1.00 62.22  ? 231 LYS B CD  1 
ATOM   5257 C  CE  . LYS B 1 231 ? 100.462 134.605 152.711 1.00 62.22  ? 231 LYS B CE  1 
ATOM   5258 N  NZ  . LYS B 1 231 ? 99.066  134.093 152.779 1.00 62.22  ? 231 LYS B NZ  1 
ATOM   5259 N  N   . LYS B 1 232 ? 102.599 129.454 151.118 1.00 55.27  ? 232 LYS B N   1 
ATOM   5260 C  CA  . LYS B 1 232 ? 103.328 128.351 151.734 1.00 55.27  ? 232 LYS B CA  1 
ATOM   5261 C  C   . LYS B 1 232 ? 104.071 127.516 150.699 1.00 55.27  ? 232 LYS B C   1 
ATOM   5262 O  O   . LYS B 1 232 ? 105.185 127.048 150.965 1.00 55.27  ? 232 LYS B O   1 
ATOM   5263 C  CB  . LYS B 1 232 ? 102.367 127.469 152.531 1.00 55.27  ? 232 LYS B CB  1 
ATOM   5264 C  CG  . LYS B 1 232 ? 103.032 126.641 153.617 1.00 55.27  ? 232 LYS B CG  1 
ATOM   5265 C  CD  . LYS B 1 232 ? 103.838 127.513 154.563 1.00 55.27  ? 232 LYS B CD  1 
ATOM   5266 C  CE  . LYS B 1 232 ? 104.295 126.725 155.779 1.00 55.27  ? 232 LYS B CE  1 
ATOM   5267 N  NZ  . LYS B 1 232 ? 103.190 125.916 156.362 1.00 55.27  ? 232 LYS B NZ  1 
ATOM   5268 N  N   . GLY B 1 233 ? 103.475 127.316 149.523 1.00 50.22  ? 233 GLY B N   1 
ATOM   5269 C  CA  . GLY B 1 233 ? 104.092 126.451 148.531 1.00 50.22  ? 233 GLY B CA  1 
ATOM   5270 C  C   . GLY B 1 233 ? 105.430 126.974 148.044 1.00 50.22  ? 233 GLY B C   1 
ATOM   5271 O  O   . GLY B 1 233 ? 106.406 126.224 147.954 1.00 50.22  ? 233 GLY B O   1 
ATOM   5272 N  N   . HIS B 1 234 ? 105.501 128.270 147.735 1.00 49.95  ? 234 HIS B N   1 
ATOM   5273 C  CA  . HIS B 1 234 ? 106.737 128.816 147.181 1.00 49.95  ? 234 HIS B CA  1 
ATOM   5274 C  C   . HIS B 1 234 ? 107.837 128.879 148.235 1.00 49.95  ? 234 HIS B C   1 
ATOM   5275 O  O   . HIS B 1 234 ? 109.009 128.634 147.927 1.00 49.95  ? 234 HIS B O   1 
ATOM   5276 C  CB  . HIS B 1 234 ? 106.480 130.191 146.560 1.00 49.95  ? 234 HIS B CB  1 
ATOM   5277 C  CG  . HIS B 1 234 ? 106.517 131.324 147.537 1.00 49.95  ? 234 HIS B CG  1 
ATOM   5278 N  ND1 . HIS B 1 234 ? 105.390 131.795 148.175 1.00 49.95  ? 234 HIS B ND1 1 
ATOM   5279 C  CD2 . HIS B 1 234 ? 107.543 132.095 147.969 1.00 49.95  ? 234 HIS B CD2 1 
ATOM   5280 C  CE1 . HIS B 1 234 ? 105.721 132.800 148.966 1.00 49.95  ? 234 HIS B CE1 1 
ATOM   5281 N  NE2 . HIS B 1 234 ? 107.022 133.001 148.861 1.00 49.95  ? 234 HIS B NE2 1 
ATOM   5282 N  N   . VAL B 1 235 ? 107.485 129.189 149.485 1.00 42.75  ? 235 VAL B N   1 
ATOM   5283 C  CA  . VAL B 1 235 ? 108.501 129.217 150.532 1.00 42.75  ? 235 VAL B CA  1 
ATOM   5284 C  C   . VAL B 1 235 ? 108.996 127.806 150.834 1.00 42.75  ? 235 VAL B C   1 
ATOM   5285 O  O   . VAL B 1 235 ? 110.189 127.597 151.085 1.00 42.75  ? 235 VAL B O   1 
ATOM   5286 C  CB  . VAL B 1 235 ? 107.978 129.939 151.790 1.00 42.75  ? 235 VAL B CB  1 
ATOM   5287 C  CG1 . VAL B 1 235 ? 106.876 129.154 152.473 1.00 42.75  ? 235 VAL B CG1 1 
ATOM   5288 C  CG2 . VAL B 1 235 ? 109.116 130.209 152.756 1.00 42.75  ? 235 VAL B CG2 1 
ATOM   5289 N  N   . THR B 1 236 ? 108.104 126.810 150.790 1.00 37.83  ? 236 THR B N   1 
ATOM   5290 C  CA  . THR B 1 236 ? 108.548 125.430 150.960 1.00 37.83  ? 236 THR B CA  1 
ATOM   5291 C  C   . THR B 1 236 ? 109.445 124.997 149.807 1.00 37.83  ? 236 THR B C   1 
ATOM   5292 O  O   . THR B 1 236 ? 110.431 124.281 150.017 1.00 37.83  ? 236 THR B O   1 
ATOM   5293 C  CB  . THR B 1 236 ? 107.343 124.499 151.084 1.00 37.83  ? 236 THR B CB  1 
ATOM   5294 O  OG1 . THR B 1 236 ? 106.490 124.961 152.137 1.00 37.83  ? 236 THR B OG1 1 
ATOM   5295 C  CG2 . THR B 1 236 ? 107.798 123.087 151.407 1.00 37.83  ? 236 THR B CG2 1 
ATOM   5296 N  N   . ARG B 1 237 ? 109.120 125.418 148.583 1.00 37.69  ? 237 ARG B N   1 
ATOM   5297 C  CA  . ARG B 1 237 ? 109.973 125.105 147.442 1.00 37.69  ? 237 ARG B CA  1 
ATOM   5298 C  C   . ARG B 1 237 ? 111.351 125.734 147.594 1.00 37.69  ? 237 ARG B C   1 
ATOM   5299 O  O   . ARG B 1 237 ? 112.367 125.096 147.303 1.00 37.69  ? 237 ARG B O   1 
ATOM   5300 C  CB  . ARG B 1 237 ? 109.314 125.575 146.147 1.00 37.69  ? 237 ARG B CB  1 
ATOM   5301 C  CG  . ARG B 1 237 ? 108.230 124.652 145.626 1.00 37.69  ? 237 ARG B CG  1 
ATOM   5302 C  CD  . ARG B 1 237 ? 107.343 125.371 144.628 1.00 37.69  ? 237 ARG B CD  1 
ATOM   5303 N  NE  . ARG B 1 237 ? 106.207 124.557 144.215 1.00 37.69  ? 237 ARG B NE  1 
ATOM   5304 C  CZ  . ARG B 1 237 ? 105.134 125.033 143.598 1.00 37.69  ? 237 ARG B CZ  1 
ATOM   5305 N  NH1 . ARG B 1 237 ? 105.015 126.319 143.313 1.00 37.69  ? 237 ARG B NH1 1 
ATOM   5306 N  NH2 . ARG B 1 237 ? 104.156 124.198 143.261 1.00 37.69  ? 237 ARG B NH2 1 
ATOM   5307 N  N   . LYS B 1 238 ? 111.403 126.991 148.042 1.00 31.67  ? 238 LYS B N   1 
ATOM   5308 C  CA  . LYS B 1 238 ? 112.690 127.643 148.268 1.00 31.67  ? 238 LYS B CA  1 
ATOM   5309 C  C   . LYS B 1 238 ? 113.487 126.932 149.354 1.00 31.67  ? 238 LYS B C   1 
ATOM   5310 O  O   . LYS B 1 238 ? 114.702 126.742 149.221 1.00 31.67  ? 238 LYS B O   1 
ATOM   5311 C  CB  . LYS B 1 238 ? 112.475 129.111 148.637 1.00 31.67  ? 238 LYS B CB  1 
ATOM   5312 C  CG  . LYS B 1 238 ? 112.001 129.980 147.485 1.00 31.67  ? 238 LYS B CG  1 
ATOM   5313 C  CD  . LYS B 1 238 ? 111.537 131.342 147.974 1.00 31.67  ? 238 LYS B CD  1 
ATOM   5314 C  CE  . LYS B 1 238 ? 111.260 132.280 146.810 1.00 31.67  ? 238 LYS B CE  1 
ATOM   5315 N  NZ  . LYS B 1 238 ? 110.510 131.605 145.716 1.00 31.67  ? 238 LYS B NZ  1 
ATOM   5316 N  N   . LEU B 1 239 ? 112.818 126.529 150.437 1.00 29.79  ? 239 LEU B N   1 
ATOM   5317 C  CA  . LEU B 1 239 ? 113.496 125.813 151.513 1.00 29.79  ? 239 LEU B CA  1 
ATOM   5318 C  C   . LEU B 1 239 ? 114.064 124.489 151.020 1.00 29.79  ? 239 LEU B C   1 
ATOM   5319 O  O   . LEU B 1 239 ? 115.205 124.133 151.335 1.00 29.79  ? 239 LEU B O   1 
ATOM   5320 C  CB  . LEU B 1 239 ? 112.528 125.585 152.672 1.00 29.79  ? 239 LEU B CB  1 
ATOM   5321 C  CG  . LEU B 1 239 ? 113.046 124.704 153.804 1.00 29.79  ? 239 LEU B CG  1 
ATOM   5322 C  CD1 . LEU B 1 239 ? 114.194 125.384 154.525 1.00 29.79  ? 239 LEU B CD1 1 
ATOM   5323 C  CD2 . LEU B 1 239 ? 111.922 124.372 154.762 1.00 29.79  ? 239 LEU B CD2 1 
ATOM   5324 N  N   . THR B 1 240 ? 113.272 123.740 150.250 1.00 28.06  ? 240 THR B N   1 
ATOM   5325 C  CA  . THR B 1 240 ? 113.746 122.471 149.710 1.00 28.06  ? 240 THR B CA  1 
ATOM   5326 C  C   . THR B 1 240 ? 114.922 122.683 148.766 1.00 28.06  ? 240 THR B C   1 
ATOM   5327 O  O   . THR B 1 240 ? 115.927 121.962 148.834 1.00 28.06  ? 240 THR B O   1 
ATOM   5328 C  CB  . THR B 1 240 ? 112.602 121.751 148.996 1.00 28.06  ? 240 THR B CB  1 
ATOM   5329 O  OG1 . THR B 1 240 ? 111.657 121.283 149.965 1.00 28.06  ? 240 THR B OG1 1 
ATOM   5330 C  CG2 . THR B 1 240 ? 113.124 120.574 148.197 1.00 28.06  ? 240 THR B CG2 1 
ATOM   5331 N  N   . CYS B 1 241 ? 114.823 123.684 147.891 1.00 28.91  ? 241 CYS B N   1 
ATOM   5332 C  CA  . CYS B 1 241 ? 115.918 123.987 146.981 1.00 28.91  ? 241 CYS B CA  1 
ATOM   5333 C  C   . CYS B 1 241 ? 117.196 124.279 147.753 1.00 28.91  ? 241 CYS B C   1 
ATOM   5334 O  O   . CYS B 1 241 ? 118.257 123.715 147.463 1.00 28.91  ? 241 CYS B O   1 
ATOM   5335 C  CB  . CYS B 1 241 ? 115.537 125.174 146.097 1.00 28.91  ? 241 CYS B CB  1 
ATOM   5336 S  SG  . CYS B 1 241 ? 114.391 124.791 144.757 1.00 28.91  ? 241 CYS B SG  1 
ATOM   5337 N  N   . LEU B 1 242 ? 117.105 125.134 148.770 1.00 25.15  ? 242 LEU B N   1 
ATOM   5338 C  CA  . LEU B 1 242 ? 118.298 125.506 149.518 1.00 25.15  ? 242 LEU B CA  1 
ATOM   5339 C  C   . LEU B 1 242 ? 118.868 124.336 150.310 1.00 25.15  ? 242 LEU B C   1 
ATOM   5340 O  O   . LEU B 1 242 ? 120.092 124.180 150.374 1.00 25.15  ? 242 LEU B O   1 
ATOM   5341 C  CB  . LEU B 1 242 ? 117.986 126.685 150.437 1.00 25.15  ? 242 LEU B CB  1 
ATOM   5342 C  CG  . LEU B 1 242 ? 117.992 128.030 149.713 1.00 25.15  ? 242 LEU B CG  1 
ATOM   5343 C  CD1 . LEU B 1 242 ? 117.540 129.137 150.631 1.00 25.15  ? 242 LEU B CD1 1 
ATOM   5344 C  CD2 . LEU B 1 242 ? 119.379 128.324 149.178 1.00 25.15  ? 242 LEU B CD2 1 
ATOM   5345 N  N   . CYS B 1 243 ? 118.017 123.502 150.913 1.00 26.59  ? 243 CYS B N   1 
ATOM   5346 C  CA  . CYS B 1 243 ? 118.537 122.393 151.707 1.00 26.59  ? 243 CYS B CA  1 
ATOM   5347 C  C   . CYS B 1 243 ? 119.219 121.359 150.821 1.00 26.59  ? 243 CYS B C   1 
ATOM   5348 O  O   . CYS B 1 243 ? 120.222 120.757 151.221 1.00 26.59  ? 243 CYS B O   1 
ATOM   5349 C  CB  . CYS B 1 243 ? 117.430 121.750 152.545 1.00 26.59  ? 243 CYS B CB  1 
ATOM   5350 S  SG  . CYS B 1 243 ? 116.109 120.945 151.641 1.00 26.59  ? 243 CYS B SG  1 
ATOM   5351 N  N   . ILE B 1 244 ? 118.687 121.123 149.617 1.00 25.10  ? 244 ILE B N   1 
ATOM   5352 C  CA  . ILE B 1 244 ? 119.392 120.254 148.677 1.00 25.10  ? 244 ILE B CA  1 
ATOM   5353 C  C   . ILE B 1 244 ? 120.702 120.893 148.227 1.00 25.10  ? 244 ILE B C   1 
ATOM   5354 O  O   . ILE B 1 244 ? 121.735 120.219 148.127 1.00 25.10  ? 244 ILE B O   1 
ATOM   5355 C  CB  . ILE B 1 244 ? 118.494 119.895 147.478 1.00 25.10  ? 244 ILE B CB  1 
ATOM   5356 C  CG1 . ILE B 1 244 ? 117.150 119.345 147.955 1.00 25.10  ? 244 ILE B CG1 1 
ATOM   5357 C  CG2 . ILE B 1 244 ? 119.190 118.903 146.567 1.00 25.10  ? 244 ILE B CG2 1 
ATOM   5358 C  CD1 . ILE B 1 244 ? 117.272 118.146 148.860 1.00 25.10  ? 244 ILE B CD1 1 
ATOM   5359 N  N   . ALA B 1 245 ? 120.685 122.198 147.947 1.00 22.51  ? 245 ALA B N   1 
ATOM   5360 C  CA  . ALA B 1 245 ? 121.895 122.872 147.485 1.00 22.51  ? 245 ALA B CA  1 
ATOM   5361 C  C   . ALA B 1 245 ? 122.955 122.929 148.575 1.00 22.51  ? 245 ALA B C   1 
ATOM   5362 O  O   . ALA B 1 245 ? 124.142 122.709 148.309 1.00 22.51  ? 245 ALA B O   1 
ATOM   5363 C  CB  . ALA B 1 245 ? 121.558 124.281 147.002 1.00 22.51  ? 245 ALA B CB  1 
ATOM   5364 N  N   . TYR B 1 246 ? 122.549 123.217 149.809 1.00 23.13  ? 246 TYR B N   1 
ATOM   5365 C  CA  . TYR B 1 246 ? 123.483 123.418 150.908 1.00 23.13  ? 246 TYR B CA  1 
ATOM   5366 C  C   . TYR B 1 246 ? 123.906 122.120 151.574 1.00 23.13  ? 246 TYR B C   1 
ATOM   5367 O  O   . TYR B 1 246 ? 124.638 122.162 152.567 1.00 23.13  ? 246 TYR B O   1 
ATOM   5368 C  CB  . TYR B 1 246 ? 122.880 124.356 151.957 1.00 23.13  ? 246 TYR B CB  1 
ATOM   5369 C  CG  . TYR B 1 246 ? 122.822 125.801 151.524 1.00 23.13  ? 246 TYR B CG  1 
ATOM   5370 C  CD1 . TYR B 1 246 ? 123.349 126.201 150.307 1.00 23.13  ? 246 TYR B CD1 1 
ATOM   5371 C  CD2 . TYR B 1 246 ? 122.240 126.764 152.332 1.00 23.13  ? 246 TYR B CD2 1 
ATOM   5372 C  CE1 . TYR B 1 246 ? 123.298 127.515 149.906 1.00 23.13  ? 246 TYR B CE1 1 
ATOM   5373 C  CE2 . TYR B 1 246 ? 122.185 128.083 151.939 1.00 23.13  ? 246 TYR B CE2 1 
ATOM   5374 C  CZ  . TYR B 1 246 ? 122.717 128.452 150.725 1.00 23.13  ? 246 TYR B CZ  1 
ATOM   5375 O  OH  . TYR B 1 246 ? 122.668 129.765 150.322 1.00 23.13  ? 246 TYR B OH  1 
ATOM   5376 N  N   . SER B 1 247 ? 123.464 120.973 151.066 1.00 25.36  ? 247 SER B N   1 
ATOM   5377 C  CA  . SER B 1 247 ? 123.936 119.702 151.593 1.00 25.36  ? 247 SER B CA  1 
ATOM   5378 C  C   . SER B 1 247 ? 125.280 119.353 150.968 1.00 25.36  ? 247 SER B C   1 
ATOM   5379 O  O   . SER B 1 247 ? 125.465 118.258 150.427 1.00 25.36  ? 247 SER B O   1 
ATOM   5380 C  CB  . SER B 1 247 ? 122.912 118.598 151.341 1.00 25.36  ? 247 SER B CB  1 
ATOM   5381 O  OG  . SER B 1 247 ? 121.742 118.818 152.106 1.00 25.36  ? 247 SER B OG  1 
ATOM   5382 N  N   . SER B 1 248 ? 126.215 120.299 151.026 1.00 30.70  ? 248 SER B N   1 
ATOM   5383 C  CA  . SER B 1 248 ? 127.619 120.059 150.739 1.00 30.70  ? 248 SER B CA  1 
ATOM   5384 C  C   . SER B 1 248 ? 128.425 119.866 152.011 1.00 30.70  ? 248 SER B C   1 
ATOM   5385 O  O   . SER B 1 248 ? 129.624 119.585 151.937 1.00 30.70  ? 248 SER B O   1 
ATOM   5386 C  CB  . SER B 1 248 ? 128.205 121.222 149.933 1.00 30.70  ? 248 SER B CB  1 
ATOM   5387 O  OG  . SER B 1 248 ? 127.563 121.351 148.679 1.00 30.70  ? 248 SER B OG  1 
ATOM   5388 N  N   . THR B 1 249 ? 127.788 120.016 153.174 1.00 31.16  ? 249 THR B N   1 
ATOM   5389 C  CA  . THR B 1 249 ? 128.503 119.920 154.440 1.00 31.16  ? 249 THR B CA  1 
ATOM   5390 C  C   . THR B 1 249 ? 129.046 118.517 154.675 1.00 31.16  ? 249 THR B C   1 
ATOM   5391 O  O   . THR B 1 249 ? 130.166 118.359 155.171 1.00 31.16  ? 249 THR B O   1 
ATOM   5392 C  CB  . THR B 1 249 ? 127.593 120.357 155.587 1.00 31.16  ? 249 THR B CB  1 
ATOM   5393 O  OG1 . THR B 1 249 ? 128.280 120.191 156.833 1.00 31.16  ? 249 THR B OG1 1 
ATOM   5394 C  CG2 . THR B 1 249 ? 126.298 119.566 155.595 1.00 31.16  ? 249 THR B CG2 1 
ATOM   5395 N  N   . ILE B 1 250 ? 128.274 117.487 154.333 1.00 33.86  ? 250 ILE B N   1 
ATOM   5396 C  CA  . ILE B 1 250 ? 128.775 116.122 154.425 1.00 33.86  ? 250 ILE B CA  1 
ATOM   5397 C  C   . ILE B 1 250 ? 129.417 115.677 153.117 1.00 33.86  ? 250 ILE B C   1 
ATOM   5398 O  O   . ILE B 1 250 ? 130.361 114.873 153.136 1.00 33.86  ? 250 ILE B O   1 
ATOM   5399 C  CB  . ILE B 1 250 ? 127.647 115.147 154.810 1.00 33.86  ? 250 ILE B CB  1 
ATOM   5400 C  CG1 . ILE B 1 250 ? 126.993 115.538 156.139 1.00 33.86  ? 250 ILE B CG1 1 
ATOM   5401 C  CG2 . ILE B 1 250 ? 128.181 113.744 154.943 1.00 33.86  ? 250 ILE B CG2 1 
ATOM   5402 C  CD1 . ILE B 1 250 ? 127.900 115.453 157.326 1.00 33.86  ? 250 ILE B CD1 1 
ATOM   5403 N  N   . GLY B 1 251 ? 128.962 116.207 151.989 1.00 35.30  ? 251 GLY B N   1 
ATOM   5404 C  CA  . GLY B 1 251 ? 129.426 115.761 150.693 1.00 35.30  ? 251 GLY B CA  1 
ATOM   5405 C  C   . GLY B 1 251 ? 130.758 116.344 150.282 1.00 35.30  ? 251 GLY B C   1 
ATOM   5406 O  O   . GLY B 1 251 ? 130.817 117.277 149.476 1.00 35.30  ? 251 GLY B O   1 
ATOM   5407 N  N   . GLY B 1 252 ? 131.843 115.809 150.843 1.00 35.69  ? 252 GLY B N   1 
ATOM   5408 C  CA  . GLY B 1 252 ? 133.194 116.225 150.515 1.00 35.69  ? 252 GLY B CA  1 
ATOM   5409 C  C   . GLY B 1 252 ? 134.018 116.594 151.731 1.00 35.69  ? 252 GLY B C   1 
ATOM   5410 O  O   . GLY B 1 252 ? 135.219 116.308 151.770 1.00 35.69  ? 252 GLY B O   1 
ATOM   5411 N  N   . LEU B 1 253 ? 133.395 117.222 152.725 1.00 30.55  ? 253 LEU B N   1 
ATOM   5412 C  CA  . LEU B 1 253 ? 134.097 117.463 153.976 1.00 30.55  ? 253 LEU B CA  1 
ATOM   5413 C  C   . LEU B 1 253 ? 134.474 116.147 154.639 1.00 30.55  ? 253 LEU B C   1 
ATOM   5414 O  O   . LEU B 1 253 ? 135.585 115.999 155.161 1.00 30.55  ? 253 LEU B O   1 
ATOM   5415 C  CB  . LEU B 1 253 ? 133.230 118.304 154.911 1.00 30.55  ? 253 LEU B CB  1 
ATOM   5416 C  CG  . LEU B 1 253 ? 133.298 119.826 154.797 1.00 30.55  ? 253 LEU B CG  1 
ATOM   5417 C  CD1 . LEU B 1 253 ? 132.702 120.292 153.483 1.00 30.55  ? 253 LEU B CD1 1 
ATOM   5418 C  CD2 . LEU B 1 253 ? 132.581 120.472 155.965 1.00 30.55  ? 253 LEU B CD2 1 
ATOM   5419 N  N   . THR B 1 254 ? 133.566 115.170 154.607 1.00 32.96  ? 254 THR B N   1 
ATOM   5420 C  CA  . THR B 1 254 ? 133.765 113.922 155.333 1.00 32.96  ? 254 THR B CA  1 
ATOM   5421 C  C   . THR B 1 254 ? 134.756 112.996 154.636 1.00 32.96  ? 254 THR B C   1 
ATOM   5422 O  O   . THR B 1 254 ? 135.529 112.301 155.304 1.00 32.96  ? 254 THR B O   1 
ATOM   5423 C  CB  . THR B 1 254 ? 132.423 113.217 155.521 1.00 32.96  ? 254 THR B CB  1 
ATOM   5424 O  OG1 . THR B 1 254 ? 131.732 113.171 154.268 1.00 32.96  ? 254 THR B OG1 1 
ATOM   5425 C  CG2 . THR B 1 254 ? 131.569 113.965 156.527 1.00 32.96  ? 254 THR B CG2 1 
ATOM   5426 N  N   . THR B 1 255 ? 134.752 112.964 153.306 1.00 33.69  ? 255 THR B N   1 
ATOM   5427 C  CA  . THR B 1 255 ? 135.594 112.053 152.543 1.00 33.69  ? 255 THR B CA  1 
ATOM   5428 C  C   . THR B 1 255 ? 136.465 112.828 151.567 1.00 33.69  ? 255 THR B C   1 
ATOM   5429 O  O   . THR B 1 255 ? 136.012 113.795 150.949 1.00 33.69  ? 255 THR B O   1 
ATOM   5430 C  CB  . THR B 1 255 ? 134.754 111.028 151.776 1.00 33.69  ? 255 THR B CB  1 
ATOM   5431 O  OG1 . THR B 1 255 ? 133.851 111.708 150.896 1.00 33.69  ? 255 THR B OG1 1 
ATOM   5432 C  CG2 . THR B 1 255 ? 133.965 110.160 152.737 1.00 33.69  ? 255 THR B CG2 1 
ATOM   5433 N  N   . ILE B 1 256 ? 137.686 112.339 151.379 1.00 36.99  ? 256 ILE B N   1 
ATOM   5434 C  CA  . ILE B 1 256 ? 138.639 113.000 150.503 1.00 36.99  ? 256 ILE B CA  1 
ATOM   5435 C  C   . ILE B 1 256 ? 138.188 113.006 149.090 1.00 36.99  ? 256 ILE B C   1 
ATOM   5436 O  O   . ILE B 1 256 ? 138.575 113.849 148.329 1.00 36.99  ? 256 ILE B O   1 
ATOM   5437 C  CB  . ILE B 1 256 ? 140.014 112.331 150.543 1.00 36.99  ? 256 ILE B CB  1 
ATOM   5438 C  CG1 . ILE B 1 256 ? 139.878 110.860 150.879 1.00 36.99  ? 256 ILE B CG1 1 
ATOM   5439 C  CG2 . ILE B 1 256 ? 140.906 112.993 151.571 1.00 36.99  ? 256 ILE B CG2 1 
ATOM   5440 C  CD1 . ILE B 1 256 ? 141.209 110.158 150.957 1.00 36.99  ? 256 ILE B CD1 1 
ATOM   5441 N  N   . THR B 1 257 ? 137.374 112.063 148.713 1.00 39.49  ? 257 THR B N   1 
ATOM   5442 C  CA  . THR B 1 257 ? 136.981 111.977 147.359 1.00 39.49  ? 257 THR B CA  1 
ATOM   5443 C  C   . THR B 1 257 ? 135.644 112.594 147.180 1.00 39.49  ? 257 THR B C   1 
ATOM   5444 O  O   . THR B 1 257 ? 135.101 112.577 146.092 1.00 39.49  ? 257 THR B O   1 
ATOM   5445 C  CB  . THR B 1 257 ? 136.862 110.517 146.960 1.00 39.49  ? 257 THR B CB  1 
ATOM   5446 O  OG1 . THR B 1 257 ? 135.707 109.948 147.580 1.00 39.49  ? 257 THR B OG1 1 
ATOM   5447 C  CG2 . THR B 1 257 ? 138.090 109.745 147.390 1.00 39.49  ? 257 THR B CG2 1 
ATOM   5448 N  N   . GLY B 1 258 ? 135.068 113.106 148.244 1.00 37.72  ? 258 GLY B N   1 
ATOM   5449 C  CA  . GLY B 1 258 ? 133.747 113.674 148.163 1.00 37.72  ? 258 GLY B CA  1 
ATOM   5450 C  C   . GLY B 1 258 ? 133.678 114.864 147.285 1.00 37.72  ? 258 GLY B C   1 
ATOM   5451 O  O   . GLY B 1 258 ? 132.727 115.006 146.564 1.00 37.72  ? 258 GLY B O   1 
ATOM   5452 N  N   . THR B 1 259 ? 134.682 115.720 147.336 1.00 37.71  ? 259 THR B N   1 
ATOM   5453 C  CA  . THR B 1 259 ? 134.715 116.934 146.569 1.00 37.71  ? 259 THR B CA  1 
ATOM   5454 C  C   . THR B 1 259 ? 136.029 117.053 145.872 1.00 37.71  ? 259 THR B C   1 
ATOM   5455 O  O   . THR B 1 259 ? 136.962 116.356 146.193 1.00 37.71  ? 259 THR B O   1 
ATOM   5456 C  CB  . THR B 1 259 ? 134.573 118.124 147.493 1.00 37.71  ? 259 THR B CB  1 
ATOM   5457 O  OG1 . THR B 1 259 ? 134.635 119.336 146.741 1.00 37.71  ? 259 THR B OG1 1 
ATOM   5458 C  CG2 . THR B 1 259 ? 135.637 118.129 148.528 1.00 37.71  ? 259 THR B CG2 1 
ATOM   5459 N  N   . SER B 1 260 ? 136.105 117.871 144.852 1.00 37.16  ? 260 SER B N   1 
ATOM   5460 C  CA  . SER B 1 260 ? 137.341 118.108 144.154 1.00 37.16  ? 260 SER B CA  1 
ATOM   5461 C  C   . SER B 1 260 ? 138.347 118.744 145.023 1.00 37.16  ? 260 SER B C   1 
ATOM   5462 O  O   . SER B 1 260 ? 139.488 118.353 144.981 1.00 37.16  ? 260 SER B O   1 
ATOM   5463 C  CB  . SER B 1 260 ? 137.054 119.073 143.041 1.00 37.16  ? 260 SER B CB  1 
ATOM   5464 O  OG  . SER B 1 260 ? 136.218 120.117 143.493 1.00 37.16  ? 260 SER B OG  1 
ATOM   5465 N  N   . THR B 1 261 ? 137.941 119.683 145.854 1.00 33.42  ? 261 THR B N   1 
ATOM   5466 C  CA  . THR B 1 261 ? 138.838 120.418 146.697 1.00 33.42  ? 261 THR B CA  1 
ATOM   5467 C  C   . THR B 1 261 ? 139.615 119.480 147.600 1.00 33.42  ? 261 THR B C   1 
ATOM   5468 O  O   . THR B 1 261 ? 140.756 119.743 147.915 1.00 33.42  ? 261 THR B O   1 
ATOM   5469 C  CB  . THR B 1 261 ? 138.028 121.388 147.528 1.00 33.42  ? 261 THR B CB  1 
ATOM   5470 O  OG1 . THR B 1 261 ? 137.114 122.078 146.682 1.00 33.42  ? 261 THR B OG1 1 
ATOM   5471 C  CG2 . THR B 1 261 ? 138.890 122.362 148.249 1.00 33.42  ? 261 THR B CG2 1 
ATOM   5472 N  N   . ASN B 1 262 ? 139.032 118.383 148.042 1.00 33.55  ? 262 ASN B N   1 
ATOM   5473 C  CA  . ASN B 1 262 ? 139.705 117.519 148.970 1.00 33.55  ? 262 ASN B CA  1 
ATOM   5474 C  C   . ASN B 1 262 ? 140.705 116.584 148.310 1.00 33.55  ? 262 ASN B C   1 
ATOM   5475 O  O   . ASN B 1 262 ? 141.645 116.191 148.956 1.00 33.55  ? 262 ASN B O   1 
ATOM   5476 C  CB  . ASN B 1 262 ? 138.676 116.856 149.834 1.00 33.55  ? 262 ASN B CB  1 
ATOM   5477 C  CG  . ASN B 1 262 ? 138.120 117.776 150.891 1.00 33.55  ? 262 ASN B CG  1 
ATOM   5478 O  OD1 . ASN B 1 262 ? 137.590 117.319 151.875 1.00 33.55  ? 262 ASN B OD1 1 
ATOM   5479 N  ND2 . ASN B 1 262 ? 138.254 119.071 150.702 1.00 33.55  ? 262 ASN B ND2 1 
ATOM   5480 N  N   . LEU B 1 263 ? 140.528 116.182 147.070 1.00 39.15  ? 263 LEU B N   1 
ATOM   5481 C  CA  . LEU B 1 263 ? 141.515 115.440 146.292 1.00 39.15  ? 263 LEU B CA  1 
ATOM   5482 C  C   . LEU B 1 263 ? 142.714 116.314 145.948 1.00 39.15  ? 263 LEU B C   1 
ATOM   5483 O  O   . LEU B 1 263 ? 143.863 115.866 146.035 1.00 39.15  ? 263 LEU B O   1 
ATOM   5484 C  CB  . LEU B 1 263 ? 140.879 114.884 145.018 1.00 39.15  ? 263 LEU B CB  1 
ATOM   5485 C  CG  . LEU B 1 263 ? 139.801 113.812 145.182 1.00 39.15  ? 263 LEU B CG  1 
ATOM   5486 C  CD1 . LEU B 1 263 ? 139.176 113.475 143.839 1.00 39.15  ? 263 LEU B CD1 1 
ATOM   5487 C  CD2 . LEU B 1 263 ? 140.387 112.568 145.827 1.00 39.15  ? 263 LEU B CD2 1 
ATOM   5488 N  N   . ILE B 1 264 ? 142.464 117.565 145.556 1.00 38.61  ? 264 ILE B N   1 
ATOM   5489 C  CA  . ILE B 1 264 ? 143.556 118.480 145.238 1.00 38.61  ? 264 ILE B CA  1 
ATOM   5490 C  C   . ILE B 1 264 ? 144.416 118.730 146.467 1.00 38.61  ? 264 ILE B C   1 
ATOM   5491 O  O   . ILE B 1 264 ? 145.652 118.710 146.395 1.00 38.61  ? 264 ILE B O   1 
ATOM   5492 C  CB  . ILE B 1 264 ? 142.998 119.795 144.663 1.00 38.61  ? 264 ILE B CB  1 
ATOM   5493 C  CG1 . ILE B 1 264 ? 142.487 119.577 143.241 1.00 38.61  ? 264 ILE B CG1 1 
ATOM   5494 C  CG2 . ILE B 1 264 ? 144.056 120.883 144.687 1.00 38.61  ? 264 ILE B CG2 1 
ATOM   5495 C  CD1 . ILE B 1 264 ? 141.772 120.771 142.674 1.00 38.61  ? 264 ILE B CD1 1 
ATOM   5496 N  N   . PHE B 1 265 ? 143.778 118.971 147.614 1.00 37.01  ? 265 PHE B N   1 
ATOM   5497 C  CA  . PHE B 1 265 ? 144.538 119.212 148.835 1.00 37.01  ? 265 PHE B CA  1 
ATOM   5498 C  C   . PHE B 1 265 ? 145.369 117.994 149.216 1.00 37.01  ? 265 PHE B C   1 
ATOM   5499 O  O   . PHE B 1 265 ? 146.539 118.128 149.593 1.00 37.01  ? 265 PHE B O   1 
ATOM   5500 C  CB  . PHE B 1 265 ? 143.601 119.595 149.978 1.00 37.01  ? 265 PHE B CB  1 
ATOM   5501 C  CG  . PHE B 1 265 ? 144.254 119.562 151.328 1.00 37.01  ? 265 PHE B CG  1 
ATOM   5502 C  CD1 . PHE B 1 265 ? 145.399 120.297 151.576 1.00 37.01  ? 265 PHE B CD1 1 
ATOM   5503 C  CD2 . PHE B 1 265 ? 143.728 118.791 152.347 1.00 37.01  ? 265 PHE B CD2 1 
ATOM   5504 C  CE1 . PHE B 1 265 ? 146.004 120.264 152.813 1.00 37.01  ? 265 PHE B CE1 1 
ATOM   5505 C  CE2 . PHE B 1 265 ? 144.330 118.758 153.587 1.00 37.01  ? 265 PHE B CE2 1 
ATOM   5506 C  CZ  . PHE B 1 265 ? 145.469 119.494 153.820 1.00 37.01  ? 265 PHE B CZ  1 
ATOM   5507 N  N   . ALA B 1 266 ? 144.784 116.798 149.124 1.00 41.15  ? 266 ALA B N   1 
ATOM   5508 C  CA  . ALA B 1 266 ? 145.520 115.587 149.469 1.00 41.15  ? 266 ALA B CA  1 
ATOM   5509 C  C   . ALA B 1 266 ? 146.702 115.375 148.535 1.00 41.15  ? 266 ALA B C   1 
ATOM   5510 O  O   . ALA B 1 266 ? 147.800 115.026 148.983 1.00 41.15  ? 266 ALA B O   1 
ATOM   5511 C  CB  . ALA B 1 266 ? 144.587 114.378 149.440 1.00 41.15  ? 266 ALA B CB  1 
ATOM   5512 N  N   . GLU B 1 267 ? 146.499 115.583 147.231 1.00 45.11  ? 267 GLU B N   1 
ATOM   5513 C  CA  . GLU B 1 267 ? 147.593 115.417 146.280 1.00 45.11  ? 267 GLU B CA  1 
ATOM   5514 C  C   . GLU B 1 267 ? 148.712 116.412 146.549 1.00 45.11  ? 267 GLU B C   1 
ATOM   5515 O  O   . GLU B 1 267 ? 149.894 116.045 146.547 1.00 45.11  ? 267 GLU B O   1 
ATOM   5516 C  CB  . GLU B 1 267 ? 147.074 115.566 144.851 1.00 45.11  ? 267 GLU B CB  1 
ATOM   5517 C  CG  . GLU B 1 267 ? 146.298 114.365 144.347 1.00 45.11  ? 267 GLU B CG  1 
ATOM   5518 C  CD  . GLU B 1 267 ? 145.189 114.750 143.392 1.00 45.11  ? 267 GLU B CD  1 
ATOM   5519 O  OE1 . GLU B 1 267 ? 145.453 115.537 142.459 1.00 45.11  ? 267 GLU B OE1 1 
ATOM   5520 O  OE2 . GLU B 1 267 ? 144.051 114.268 143.577 1.00 45.11  ? 267 GLU B OE2 1 
ATOM   5521 N  N   . TYR B 1 268 ? 148.360 117.678 146.790 1.00 43.31  ? 268 TYR B N   1 
ATOM   5522 C  CA  . TYR B 1 268 ? 149.381 118.681 147.066 1.00 43.31  ? 268 TYR B CA  1 
ATOM   5523 C  C   . TYR B 1 268 ? 150.137 118.359 148.348 1.00 43.31  ? 268 TYR B C   1 
ATOM   5524 O  O   . TYR B 1 268 ? 151.364 118.494 148.402 1.00 43.31  ? 268 TYR B O   1 
ATOM   5525 C  CB  . TYR B 1 268 ? 148.754 120.070 147.157 1.00 43.31  ? 268 TYR B CB  1 
ATOM   5526 C  CG  . TYR B 1 268 ? 149.749 121.141 147.535 1.00 43.31  ? 268 TYR B CG  1 
ATOM   5527 C  CD1 . TYR B 1 268 ? 150.662 121.623 146.608 1.00 43.31  ? 268 TYR B CD1 1 
ATOM   5528 C  CD2 . TYR B 1 268 ? 149.791 121.656 148.822 1.00 43.31  ? 268 TYR B CD2 1 
ATOM   5529 C  CE1 . TYR B 1 268 ? 151.578 122.596 146.948 1.00 43.31  ? 268 TYR B CE1 1 
ATOM   5530 C  CE2 . TYR B 1 268 ? 150.704 122.627 149.172 1.00 43.31  ? 268 TYR B CE2 1 
ATOM   5531 C  CZ  . TYR B 1 268 ? 151.595 123.094 148.231 1.00 43.31  ? 268 TYR B CZ  1 
ATOM   5532 O  OH  . TYR B 1 268 ? 152.508 124.063 148.574 1.00 43.31  ? 268 TYR B OH  1 
ATOM   5533 N  N   . PHE B 1 269 ? 149.422 117.940 149.394 1.00 46.25  ? 269 PHE B N   1 
ATOM   5534 C  CA  . PHE B 1 269 ? 150.084 117.620 150.652 1.00 46.25  ? 269 PHE B CA  1 
ATOM   5535 C  C   . PHE B 1 269 ? 151.011 116.422 150.504 1.00 46.25  ? 269 PHE B C   1 
ATOM   5536 O  O   . PHE B 1 269 ? 152.128 116.428 151.034 1.00 46.25  ? 269 PHE B O   1 
ATOM   5537 C  CB  . PHE B 1 269 ? 149.047 117.365 151.743 1.00 46.25  ? 269 PHE B CB  1 
ATOM   5538 C  CG  . PHE B 1 269 ? 149.636 117.255 153.114 1.00 46.25  ? 269 PHE B CG  1 
ATOM   5539 C  CD1 . PHE B 1 269 ? 149.996 118.389 153.818 1.00 46.25  ? 269 PHE B CD1 1 
ATOM   5540 C  CD2 . PHE B 1 269 ? 149.840 116.018 153.696 1.00 46.25  ? 269 PHE B CD2 1 
ATOM   5541 C  CE1 . PHE B 1 269 ? 150.545 118.291 155.075 1.00 46.25  ? 269 PHE B CE1 1 
ATOM   5542 C  CE2 . PHE B 1 269 ? 150.386 115.913 154.955 1.00 46.25  ? 269 PHE B CE2 1 
ATOM   5543 C  CZ  . PHE B 1 269 ? 150.740 117.051 155.646 1.00 46.25  ? 269 PHE B CZ  1 
ATOM   5544 N  N   . ASN B 1 270 ? 150.567 115.382 149.794 1.00 47.64  ? 270 ASN B N   1 
ATOM   5545 C  CA  . ASN B 1 270 ? 151.415 114.212 149.596 1.00 47.64  ? 270 ASN B CA  1 
ATOM   5546 C  C   . ASN B 1 270 ? 152.647 114.553 148.770 1.00 47.64  ? 270 ASN B C   1 
ATOM   5547 O  O   . ASN B 1 270 ? 153.749 114.077 149.065 1.00 47.64  ? 270 ASN B O   1 
ATOM   5548 C  CB  . ASN B 1 270 ? 150.617 113.090 148.935 1.00 47.64  ? 270 ASN B CB  1 
ATOM   5549 C  CG  . ASN B 1 270 ? 149.499 112.578 149.816 1.00 47.64  ? 270 ASN B CG  1 
ATOM   5550 O  OD1 . ASN B 1 270 ? 149.465 112.849 151.015 1.00 47.64  ? 270 ASN B OD1 1 
ATOM   5551 N  ND2 . ASN B 1 270 ? 148.575 111.832 149.224 1.00 47.64  ? 270 ASN B ND2 1 
ATOM   5552 N  N   . THR B 1 271 ? 152.484 115.372 147.728 1.00 49.15  ? 271 THR B N   1 
ATOM   5553 C  CA  . THR B 1 271 ? 153.628 115.750 146.906 1.00 49.15  ? 271 THR B CA  1 
ATOM   5554 C  C   . THR B 1 271 ? 154.617 116.601 147.693 1.00 49.15  ? 271 THR B C   1 
ATOM   5555 O  O   . THR B 1 271 ? 155.829 116.358 147.655 1.00 49.15  ? 271 THR B O   1 
ATOM   5556 C  CB  . THR B 1 271 ? 153.153 116.492 145.657 1.00 49.15  ? 271 THR B CB  1 
ATOM   5557 O  OG1 . THR B 1 271 ? 152.289 115.642 144.894 1.00 49.15  ? 271 THR B OG1 1 
ATOM   5558 C  CG2 . THR B 1 271 ? 154.338 116.903 144.798 1.00 49.15  ? 271 THR B CG2 1 
ATOM   5559 N  N   . ARG B 1 272 ? 154.120 117.605 148.418 1.00 49.90  ? 272 ARG B N   1 
ATOM   5560 C  CA  . ARG B 1 272 ? 155.007 118.507 149.142 1.00 49.90  ? 272 ARG B CA  1 
ATOM   5561 C  C   . ARG B 1 272 ? 155.548 117.886 150.424 1.00 49.90  ? 272 ARG B C   1 
ATOM   5562 O  O   . ARG B 1 272 ? 156.655 118.230 150.852 1.00 49.90  ? 272 ARG B O   1 
ATOM   5563 C  CB  . ARG B 1 272 ? 154.285 119.817 149.455 1.00 49.90  ? 272 ARG B CB  1 
ATOM   5564 C  CG  . ARG B 1 272 ? 155.215 121.007 149.597 1.00 49.90  ? 272 ARG B CG  1 
ATOM   5565 C  CD  . ARG B 1 272 ? 154.648 122.049 150.541 1.00 49.90  ? 272 ARG B CD  1 
ATOM   5566 N  NE  . ARG B 1 272 ? 155.678 122.948 151.044 1.00 49.90  ? 272 ARG B NE  1 
ATOM   5567 C  CZ  . ARG B 1 272 ? 155.908 124.165 150.570 1.00 49.90  ? 272 ARG B CZ  1 
ATOM   5568 N  NH1 . ARG B 1 272 ? 155.198 124.663 149.572 1.00 49.90  ? 272 ARG B NH1 1 
ATOM   5569 N  NH2 . ARG B 1 272 ? 156.874 124.900 151.113 1.00 49.90  ? 272 ARG B NH2 1 
ATOM   5570 N  N   . TYR B 1 273 ? 154.795 116.982 151.049 1.00 52.37  ? 273 TYR B N   1 
ATOM   5571 C  CA  . TYR B 1 273 ? 155.210 116.317 152.285 1.00 52.37  ? 273 TYR B CA  1 
ATOM   5572 C  C   . TYR B 1 273 ? 155.090 114.811 152.100 1.00 52.37  ? 273 TYR B C   1 
ATOM   5573 O  O   . TYR B 1 273 ? 154.148 114.183 152.603 1.00 52.37  ? 273 TYR B O   1 
ATOM   5574 C  CB  . TYR B 1 273 ? 154.374 116.782 153.478 1.00 52.37  ? 273 TYR B CB  1 
ATOM   5575 C  CG  . TYR B 1 273 ? 154.376 118.275 153.703 1.00 52.37  ? 273 TYR B CG  1 
ATOM   5576 C  CD1 . TYR B 1 273 ? 155.364 118.880 154.464 1.00 52.37  ? 273 TYR B CD1 1 
ATOM   5577 C  CD2 . TYR B 1 273 ? 153.379 119.077 153.167 1.00 52.37  ? 273 TYR B CD2 1 
ATOM   5578 C  CE1 . TYR B 1 273 ? 155.366 120.243 154.679 1.00 52.37  ? 273 TYR B CE1 1 
ATOM   5579 C  CE2 . TYR B 1 273 ? 153.371 120.441 153.378 1.00 52.37  ? 273 TYR B CE2 1 
ATOM   5580 C  CZ  . TYR B 1 273 ? 154.367 121.018 154.133 1.00 52.37  ? 273 TYR B CZ  1 
ATOM   5581 O  OH  . TYR B 1 273 ? 154.364 122.376 154.343 1.00 52.37  ? 273 TYR B OH  1 
ATOM   5582 N  N   . PRO B 1 274 ? 156.027 114.196 151.374 1.00 56.16  ? 274 PRO B N   1 
ATOM   5583 C  CA  . PRO B 1 274 ? 155.969 112.736 151.198 1.00 56.16  ? 274 PRO B CA  1 
ATOM   5584 C  C   . PRO B 1 274 ? 156.076 111.966 152.501 1.00 56.16  ? 274 PRO B C   1 
ATOM   5585 O  O   . PRO B 1 274 ? 155.495 110.879 152.618 1.00 56.16  ? 274 PRO B O   1 
ATOM   5586 C  CB  . PRO B 1 274 ? 157.158 112.442 150.270 1.00 56.16  ? 274 PRO B CB  1 
ATOM   5587 C  CG  . PRO B 1 274 ? 157.566 113.766 149.702 1.00 56.16  ? 274 PRO B CG  1 
ATOM   5588 C  CD  . PRO B 1 274 ? 157.206 114.788 150.724 1.00 56.16  ? 274 PRO B CD  1 
ATOM   5589 N  N   . ASP B 1 275 ? 156.809 112.492 153.485 1.00 61.62  ? 275 ASP B N   1 
ATOM   5590 C  CA  . ASP B 1 275 ? 157.005 111.764 154.734 1.00 61.62  ? 275 ASP B CA  1 
ATOM   5591 C  C   . ASP B 1 275 ? 155.705 111.640 155.520 1.00 61.62  ? 275 ASP B C   1 
ATOM   5592 O  O   . ASP B 1 275 ? 155.440 110.596 156.127 1.00 61.62  ? 275 ASP B O   1 
ATOM   5593 C  CB  . ASP B 1 275 ? 158.081 112.448 155.575 1.00 61.62  ? 275 ASP B CB  1 
ATOM   5594 C  CG  . ASP B 1 275 ? 159.455 112.355 154.945 1.00 61.62  ? 275 ASP B CG  1 
ATOM   5595 O  OD1 . ASP B 1 275 ? 159.696 111.397 154.182 1.00 61.62  ? 275 ASP B OD1 1 
ATOM   5596 O  OD2 . ASP B 1 275 ? 160.296 113.238 155.215 1.00 61.62  ? 275 ASP B OD2 1 
ATOM   5597 N  N   . CYS B 1 276 ? 154.886 112.688 155.527 1.00 61.25  ? 276 CYS B N   1 
ATOM   5598 C  CA  . CYS B 1 276 ? 153.623 112.637 156.251 1.00 61.25  ? 276 CYS B CA  1 
ATOM   5599 C  C   . CYS B 1 276 ? 152.614 111.789 155.487 1.00 61.25  ? 276 CYS B C   1 
ATOM   5600 O  O   . CYS B 1 276 ? 152.289 112.081 154.332 1.00 61.25  ? 276 CYS B O   1 
ATOM   5601 C  CB  . CYS B 1 276 ? 153.074 114.045 156.467 1.00 61.25  ? 276 CYS B CB  1 
ATOM   5602 N  N   . ARG B 1 277 ? 152.115 110.739 156.137 1.00 63.49  ? 277 ARG B N   1 
ATOM   5603 C  CA  . ARG B 1 277 ? 151.152 109.829 155.529 1.00 63.49  ? 277 ARG B CA  1 
ATOM   5604 C  C   . ARG B 1 277 ? 149.869 109.767 156.346 1.00 63.49  ? 277 ARG B C   1 
ATOM   5605 O  O   . ARG B 1 277 ? 149.157 108.759 156.322 1.00 63.49  ? 277 ARG B O   1 
ATOM   5606 C  CB  . ARG B 1 277 ? 151.753 108.434 155.363 1.00 63.49  ? 277 ARG B CB  1 
ATOM   5607 C  CG  . ARG B 1 277 ? 152.875 108.365 154.341 1.00 63.49  ? 277 ARG B CG  1 
ATOM   5608 C  CD  . ARG B 1 277 ? 153.768 107.161 154.578 1.00 63.49  ? 277 ARG B CD  1 
ATOM   5609 N  NE  . ARG B 1 277 ? 153.009 106.003 155.034 1.00 63.49  ? 277 ARG B NE  1 
ATOM   5610 C  CZ  . ARG B 1 277 ? 152.416 105.132 154.229 1.00 63.49  ? 277 ARG B CZ  1 
ATOM   5611 N  NH1 . ARG B 1 277 ? 152.465 105.262 152.913 1.00 63.49  ? 277 ARG B NH1 1 
ATOM   5612 N  NH2 . ARG B 1 277 ? 151.756 104.106 154.758 1.00 63.49  ? 277 ARG B NH2 1 
ATOM   5613 N  N   . CYS B 1 278 ? 149.562 110.840 157.076 1.00 55.88  ? 278 CYS B N   1 
ATOM   5614 C  CA  . CYS B 1 278 ? 148.381 110.859 157.930 1.00 55.88  ? 278 CYS B CA  1 
ATOM   5615 C  C   . CYS B 1 278 ? 147.092 111.026 157.137 1.00 55.88  ? 278 CYS B C   1 
ATOM   5616 O  O   . CYS B 1 278 ? 146.054 110.487 157.536 1.00 55.88  ? 278 CYS B O   1 
ATOM   5617 C  CB  . CYS B 1 278 ? 148.505 111.978 158.965 1.00 55.88  ? 278 CYS B CB  1 
ATOM   5618 S  SG  . CYS B 1 278 ? 149.026 113.569 158.282 1.00 55.88  ? 278 CYS B SG  1 
ATOM   5619 N  N   . LEU B 1 279 ? 147.129 111.759 156.028 1.00 47.79  ? 279 LEU B N   1 
ATOM   5620 C  CA  . LEU B 1 279 ? 145.923 112.043 155.251 1.00 47.79  ? 279 LEU B CA  1 
ATOM   5621 C  C   . LEU B 1 279 ? 145.555 110.819 154.425 1.00 47.79  ? 279 LEU B C   1 
ATOM   5622 O  O   . LEU B 1 279 ? 146.190 110.521 153.411 1.00 47.79  ? 279 LEU B O   1 
ATOM   5623 C  CB  . LEU B 1 279 ? 146.129 113.264 154.363 1.00 47.79  ? 279 LEU B CB  1 
ATOM   5624 C  CG  . LEU B 1 279 ? 146.117 114.620 155.065 1.00 47.79  ? 279 LEU B CG  1 
ATOM   5625 C  CD1 . LEU B 1 279 ? 146.176 115.736 154.043 1.00 47.79  ? 279 LEU B CD1 1 
ATOM   5626 C  CD2 . LEU B 1 279 ? 144.884 114.756 155.939 1.00 47.79  ? 279 LEU B CD2 1 
ATOM   5627 N  N   . ASN B 1 280 ? 144.520 110.108 154.861 1.00 46.66  ? 280 ASN B N   1 
ATOM   5628 C  CA  . ASN B 1 280 ? 143.970 108.984 154.118 1.00 46.66  ? 280 ASN B CA  1 
ATOM   5629 C  C   . ASN B 1 280 ? 142.543 108.762 154.594 1.00 46.66  ? 280 ASN B C   1 
ATOM   5630 O  O   . ASN B 1 280 ? 142.130 109.279 155.635 1.00 46.66  ? 280 ASN B O   1 
ATOM   5631 C  CB  . ASN B 1 280 ? 144.816 107.718 154.293 1.00 46.66  ? 280 ASN B CB  1 
ATOM   5632 C  CG  . ASN B 1 280 ? 145.172 107.447 155.742 1.00 46.66  ? 280 ASN B CG  1 
ATOM   5633 O  OD1 . ASN B 1 280 ? 144.302 107.408 156.612 1.00 46.66  ? 280 ASN B OD1 1 
ATOM   5634 N  ND2 . ASN B 1 280 ? 146.458 107.250 156.007 1.00 46.66  ? 280 ASN B ND2 1 
ATOM   5635 N  N   . PHE B 1 281 ? 141.788 107.993 153.814 1.00 49.29  ? 281 PHE B N   1 
ATOM   5636 C  CA  . PHE B 1 281 ? 140.429 107.659 154.216 1.00 49.29  ? 281 PHE B CA  1 
ATOM   5637 C  C   . PHE B 1 281 ? 140.454 106.864 155.514 1.00 49.29  ? 281 PHE B C   1 
ATOM   5638 O  O   . PHE B 1 281 ? 141.301 105.990 155.711 1.00 49.29  ? 281 PHE B O   1 
ATOM   5639 C  CB  . PHE B 1 281 ? 139.720 106.862 153.122 1.00 49.29  ? 281 PHE B CB  1 
ATOM   5640 C  CG  . PHE B 1 281 ? 138.293 106.528 153.451 1.00 49.29  ? 281 PHE B CG  1 
ATOM   5641 C  CD1 . PHE B 1 281 ? 137.309 107.498 153.383 1.00 49.29  ? 281 PHE B CD1 1 
ATOM   5642 C  CD2 . PHE B 1 281 ? 137.938 105.248 153.841 1.00 49.29  ? 281 PHE B CD2 1 
ATOM   5643 C  CE1 . PHE B 1 281 ? 135.997 107.198 153.690 1.00 49.29  ? 281 PHE B CE1 1 
ATOM   5644 C  CE2 . PHE B 1 281 ? 136.627 104.943 154.149 1.00 49.29  ? 281 PHE B CE2 1 
ATOM   5645 C  CZ  . PHE B 1 281 ? 135.655 105.920 154.073 1.00 49.29  ? 281 PHE B CZ  1 
ATOM   5646 N  N   . GLY B 1 282 ? 139.517 107.175 156.404 1.00 44.93  ? 282 GLY B N   1 
ATOM   5647 C  CA  . GLY B 1 282 ? 139.523 106.624 157.739 1.00 44.93  ? 282 GLY B CA  1 
ATOM   5648 C  C   . GLY B 1 282 ? 140.259 107.465 158.756 1.00 44.93  ? 282 GLY B C   1 
ATOM   5649 O  O   . GLY B 1 282 ? 140.158 107.185 159.957 1.00 44.93  ? 282 GLY B O   1 
ATOM   5650 N  N   . SER B 1 283 ? 141.004 108.472 158.315 1.00 41.36  ? 283 SER B N   1 
ATOM   5651 C  CA  . SER B 1 283 ? 141.590 109.486 159.182 1.00 41.36  ? 283 SER B CA  1 
ATOM   5652 C  C   . SER B 1 283 ? 141.048 110.873 158.890 1.00 41.36  ? 283 SER B C   1 
ATOM   5653 O  O   . SER B 1 283 ? 140.905 111.682 159.809 1.00 41.36  ? 283 SER B O   1 
ATOM   5654 C  CB  . SER B 1 283 ? 143.118 109.492 159.043 1.00 41.36  ? 283 SER B CB  1 
ATOM   5655 O  OG  . SER B 1 283 ? 143.506 109.807 157.718 1.00 41.36  ? 283 SER B OG  1 
ATOM   5656 N  N   . TRP B 1 284 ? 140.754 111.168 157.622 1.00 34.47  ? 284 TRP B N   1 
ATOM   5657 C  CA  . TRP B 1 284 ? 139.994 112.367 157.292 1.00 34.47  ? 284 TRP B CA  1 
ATOM   5658 C  C   . TRP B 1 284 ? 138.595 112.304 157.891 1.00 34.47  ? 284 TRP B C   1 
ATOM   5659 O  O   . TRP B 1 284 ? 138.096 113.292 158.446 1.00 34.47  ? 284 TRP B O   1 
ATOM   5660 C  CB  . TRP B 1 284 ? 139.923 112.528 155.774 1.00 34.47  ? 284 TRP B CB  1 
ATOM   5661 C  CG  . TRP B 1 284 ? 139.365 113.833 155.325 1.00 34.47  ? 284 TRP B CG  1 
ATOM   5662 C  CD1 . TRP B 1 284 ? 138.050 114.186 155.268 1.00 34.47  ? 284 TRP B CD1 1 
ATOM   5663 C  CD2 . TRP B 1 284 ? 140.105 114.966 154.861 1.00 34.47  ? 284 TRP B CD2 1 
ATOM   5664 N  NE1 . TRP B 1 284 ? 137.924 115.471 154.801 1.00 34.47  ? 284 TRP B NE1 1 
ATOM   5665 C  CE2 . TRP B 1 284 ? 139.173 115.972 154.543 1.00 34.47  ? 284 TRP B CE2 1 
ATOM   5666 C  CE3 . TRP B 1 284 ? 141.466 115.229 154.685 1.00 34.47  ? 284 TRP B CE3 1 
ATOM   5667 C  CZ2 . TRP B 1 284 ? 139.558 117.218 154.062 1.00 34.47  ? 284 TRP B CZ2 1 
ATOM   5668 C  CZ3 . TRP B 1 284 ? 141.844 116.465 154.207 1.00 34.47  ? 284 TRP B CZ3 1 
ATOM   5669 C  CH2 . TRP B 1 284 ? 140.895 117.445 153.900 1.00 34.47  ? 284 TRP B CH2 1 
ATOM   5670 N  N   . PHE B 1 285 ? 137.956 111.137 157.797 1.00 32.04  ? 285 PHE B N   1 
ATOM   5671 C  CA  . PHE B 1 285 ? 136.609 110.970 158.329 1.00 32.04  ? 285 PHE B CA  1 
ATOM   5672 C  C   . PHE B 1 285 ? 136.577 111.203 159.832 1.00 32.04  ? 285 PHE B C   1 
ATOM   5673 O  O   . PHE B 1 285 ? 135.654 111.845 160.343 1.00 32.04  ? 285 PHE B O   1 
ATOM   5674 C  CB  . PHE B 1 285 ? 136.091 109.574 157.987 1.00 32.04  ? 285 PHE B CB  1 
ATOM   5675 C  CG  . PHE B 1 285 ? 134.606 109.422 158.133 1.00 32.04  ? 285 PHE B CG  1 
ATOM   5676 C  CD1 . PHE B 1 285 ? 133.758 109.753 157.091 1.00 32.04  ? 285 PHE B CD1 1 
ATOM   5677 C  CD2 . PHE B 1 285 ? 134.059 108.935 159.306 1.00 32.04  ? 285 PHE B CD2 1 
ATOM   5678 C  CE1 . PHE B 1 285 ? 132.393 109.610 157.221 1.00 32.04  ? 285 PHE B CE1 1 
ATOM   5679 C  CE2 . PHE B 1 285 ? 132.696 108.790 159.441 1.00 32.04  ? 285 PHE B CE2 1 
ATOM   5680 C  CZ  . PHE B 1 285 ? 131.862 109.127 158.396 1.00 32.04  ? 285 PHE B CZ  1 
ATOM   5681 N  N   . THR B 1 286 ? 137.592 110.718 160.552 1.00 36.54  ? 286 THR B N   1 
ATOM   5682 C  CA  . THR B 1 286 ? 137.573 110.791 162.010 1.00 36.54  ? 286 THR B CA  1 
ATOM   5683 C  C   . THR B 1 286 ? 137.501 112.230 162.503 1.00 36.54  ? 286 THR B C   1 
ATOM   5684 O  O   . THR B 1 286 ? 136.751 112.532 163.438 1.00 36.54  ? 286 THR B O   1 
ATOM   5685 C  CB  . THR B 1 286 ? 138.801 110.093 162.593 1.00 36.54  ? 286 THR B CB  1 
ATOM   5686 O  OG1 . THR B 1 286 ? 139.984 110.583 161.952 1.00 36.54  ? 286 THR B OG1 1 
ATOM   5687 C  CG2 . THR B 1 286 ? 138.702 108.592 162.400 1.00 36.54  ? 286 THR B CG2 1 
ATOM   5688 N  N   . PHE B 1 287 ? 138.270 113.134 161.899 1.00 34.59  ? 287 PHE B N   1 
ATOM   5689 C  CA  . PHE B 1 287 ? 138.238 114.519 162.344 1.00 34.59  ? 287 PHE B CA  1 
ATOM   5690 C  C   . PHE B 1 287 ? 137.201 115.354 161.608 1.00 34.59  ? 287 PHE B C   1 
ATOM   5691 O  O   . PHE B 1 287 ? 136.893 116.462 162.059 1.00 34.59  ? 287 PHE B O   1 
ATOM   5692 C  CB  . PHE B 1 287 ? 139.616 115.178 162.188 1.00 34.59  ? 287 PHE B CB  1 
ATOM   5693 C  CG  . PHE B 1 287 ? 139.874 115.756 160.820 1.00 34.59  ? 287 PHE B CG  1 
ATOM   5694 C  CD1 . PHE B 1 287 ? 140.383 114.974 159.803 1.00 34.59  ? 287 PHE B CD1 1 
ATOM   5695 C  CD2 . PHE B 1 287 ? 139.630 117.097 160.565 1.00 34.59  ? 287 PHE B CD2 1 
ATOM   5696 C  CE1 . PHE B 1 287 ? 140.625 115.514 158.553 1.00 34.59  ? 287 PHE B CE1 1 
ATOM   5697 C  CE2 . PHE B 1 287 ? 139.866 117.637 159.318 1.00 34.59  ? 287 PHE B CE2 1 
ATOM   5698 C  CZ  . PHE B 1 287 ? 140.365 116.845 158.312 1.00 34.59  ? 287 PHE B CZ  1 
ATOM   5699 N  N   . SER B 1 288 ? 136.654 114.862 160.497 1.00 30.97  ? 288 SER B N   1 
ATOM   5700 C  CA  . SER B 1 288 ? 135.741 115.676 159.707 1.00 30.97  ? 288 SER B CA  1 
ATOM   5701 C  C   . SER B 1 288 ? 134.270 115.369 159.944 1.00 30.97  ? 288 SER B C   1 
ATOM   5702 O  O   . SER B 1 288 ? 133.433 116.255 159.744 1.00 30.97  ? 288 SER B O   1 
ATOM   5703 C  CB  . SER B 1 288 ? 136.045 115.512 158.218 1.00 30.97  ? 288 SER B CB  1 
ATOM   5704 O  OG  . SER B 1 288 ? 135.251 116.399 157.456 1.00 30.97  ? 288 SER B OG  1 
ATOM   5705 N  N   . PHE B 1 289 ? 133.925 114.146 160.348 1.00 29.04  ? 289 PHE B N   1 
ATOM   5706 C  CA  . PHE B 1 289 ? 132.516 113.803 160.533 1.00 29.04  ? 289 PHE B CA  1 
ATOM   5707 C  C   . PHE B 1 289 ? 131.834 114.613 161.628 1.00 29.04  ? 289 PHE B C   1 
ATOM   5708 O  O   . PHE B 1 289 ? 130.706 115.081 161.397 1.00 29.04  ? 289 PHE B O   1 
ATOM   5709 C  CB  . PHE B 1 289 ? 132.370 112.301 160.789 1.00 29.04  ? 289 PHE B CB  1 
ATOM   5710 C  CG  . PHE B 1 289 ? 130.945 111.828 160.779 1.00 29.04  ? 289 PHE B CG  1 
ATOM   5711 C  CD1 . PHE B 1 289 ? 130.206 111.844 159.610 1.00 29.04  ? 289 PHE B CD1 1 
ATOM   5712 C  CD2 . PHE B 1 289 ? 130.339 111.383 161.942 1.00 29.04  ? 289 PHE B CD2 1 
ATOM   5713 C  CE1 . PHE B 1 289 ? 128.895 111.415 159.597 1.00 29.04  ? 289 PHE B CE1 1 
ATOM   5714 C  CE2 . PHE B 1 289 ? 129.027 110.954 161.935 1.00 29.04  ? 289 PHE B CE2 1 
ATOM   5715 C  CZ  . PHE B 1 289 ? 128.305 110.970 160.761 1.00 29.04  ? 289 PHE B CZ  1 
ATOM   5716 N  N   . PRO B 1 290 ? 132.407 114.792 162.826 1.00 27.63  ? 290 PRO B N   1 
ATOM   5717 C  CA  . PRO B 1 290 ? 131.691 115.592 163.837 1.00 27.63  ? 290 PRO B CA  1 
ATOM   5718 C  C   . PRO B 1 290 ? 131.424 117.020 163.398 1.00 27.63  ? 290 PRO B C   1 
ATOM   5719 O  O   . PRO B 1 290 ? 130.304 117.519 163.574 1.00 27.63  ? 290 PRO B O   1 
ATOM   5720 C  CB  . PRO B 1 290 ? 132.624 115.536 165.055 1.00 27.63  ? 290 PRO B CB  1 
ATOM   5721 C  CG  . PRO B 1 290 ? 133.455 114.330 164.847 1.00 27.63  ? 290 PRO B CG  1 
ATOM   5722 C  CD  . PRO B 1 290 ? 133.647 114.214 163.374 1.00 27.63  ? 290 PRO B CD  1 
ATOM   5723 N  N   . ALA B 1 291 ? 132.420 117.692 162.818 1.00 24.48  ? 291 ALA B N   1 
ATOM   5724 C  CA  . ALA B 1 291 ? 132.223 119.068 162.376 1.00 24.48  ? 291 ALA B CA  1 
ATOM   5725 C  C   . ALA B 1 291 ? 131.175 119.149 161.277 1.00 24.48  ? 291 ALA B C   1 
ATOM   5726 O  O   . ALA B 1 291 ? 130.306 120.028 161.299 1.00 24.48  ? 291 ALA B O   1 
ATOM   5727 C  CB  . ALA B 1 291 ? 133.547 119.661 161.897 1.00 24.48  ? 291 ALA B CB  1 
ATOM   5728 N  N   . ALA B 1 292 ? 131.237 118.234 160.310 1.00 26.11  ? 292 ALA B N   1 
ATOM   5729 C  CA  . ALA B 1 292 ? 130.278 118.252 159.212 1.00 26.11  ? 292 ALA B CA  1 
ATOM   5730 C  C   . ALA B 1 292 ? 128.865 117.951 159.700 1.00 26.11  ? 292 ALA B C   1 
ATOM   5731 O  O   . ALA B 1 292 ? 127.900 118.568 159.236 1.00 26.11  ? 292 ALA B O   1 
ATOM   5732 C  CB  . ALA B 1 292 ? 130.711 117.261 158.135 1.00 26.11  ? 292 ALA B CB  1 
ATOM   5733 N  N   . LEU B 1 293 ? 128.723 117.013 160.639 1.00 24.06  ? 293 LEU B N   1 
ATOM   5734 C  CA  . LEU B 1 293 ? 127.408 116.709 161.198 1.00 24.06  ? 293 LEU B CA  1 
ATOM   5735 C  C   . LEU B 1 293 ? 126.847 117.889 161.981 1.00 24.06  ? 293 LEU B C   1 
ATOM   5736 O  O   . LEU B 1 293 ? 125.648 118.185 161.898 1.00 24.06  ? 293 LEU B O   1 
ATOM   5737 C  CB  . LEU B 1 293 ? 127.494 115.471 162.089 1.00 24.06  ? 293 LEU B CB  1 
ATOM   5738 C  CG  . LEU B 1 293 ? 126.190 115.023 162.750 1.00 24.06  ? 293 LEU B CG  1 
ATOM   5739 C  CD1 . LEU B 1 293 ? 125.170 114.612 161.702 1.00 24.06  ? 293 LEU B CD1 1 
ATOM   5740 C  CD2 . LEU B 1 293 ? 126.450 113.887 163.723 1.00 24.06  ? 293 LEU B CD2 1 
ATOM   5741 N  N   . ILE B 1 294 ? 127.695 118.568 162.759 1.00 21.79  ? 294 ILE B N   1 
ATOM   5742 C  CA  . ILE B 1 294 ? 127.242 119.745 163.493 1.00 21.79  ? 294 ILE B CA  1 
ATOM   5743 C  C   . ILE B 1 294 ? 126.802 120.834 162.526 1.00 21.79  ? 294 ILE B C   1 
ATOM   5744 O  O   . ILE B 1 294 ? 125.773 121.491 162.733 1.00 21.79  ? 294 ILE B O   1 
ATOM   5745 C  CB  . ILE B 1 294 ? 128.345 120.239 164.446 1.00 21.79  ? 294 ILE B CB  1 
ATOM   5746 C  CG1 . ILE B 1 294 ? 128.529 119.256 165.601 1.00 21.79  ? 294 ILE B CG1 1 
ATOM   5747 C  CG2 . ILE B 1 294 ? 128.009 121.616 164.986 1.00 21.79  ? 294 ILE B CG2 1 
ATOM   5748 C  CD1 . ILE B 1 294 ? 129.679 119.601 166.513 1.00 21.79  ? 294 ILE B CD1 1 
ATOM   5749 N  N   . ILE B 1 295 ? 127.570 121.041 161.453 1.00 22.59  ? 295 ILE B N   1 
ATOM   5750 C  CA  . ILE B 1 295 ? 127.184 122.027 160.447 1.00 22.59  ? 295 ILE B CA  1 
ATOM   5751 C  C   . ILE B 1 295 ? 125.851 121.650 159.820 1.00 22.59  ? 295 ILE B C   1 
ATOM   5752 O  O   . ILE B 1 295 ? 124.991 122.507 159.603 1.00 22.59  ? 295 ILE B O   1 
ATOM   5753 C  CB  . ILE B 1 295 ? 128.284 122.176 159.380 1.00 22.59  ? 295 ILE B CB  1 
ATOM   5754 C  CG1 . ILE B 1 295 ? 129.553 122.758 159.993 1.00 22.59  ? 295 ILE B CG1 1 
ATOM   5755 C  CG2 . ILE B 1 295 ? 127.809 123.073 158.252 1.00 22.59  ? 295 ILE B CG2 1 
ATOM   5756 C  CD1 . ILE B 1 295 ? 130.752 122.682 159.085 1.00 22.59  ? 295 ILE B CD1 1 
ATOM   5757 N  N   . LEU B 1 296 ? 125.658 120.365 159.518 1.00 23.33  ? 296 LEU B N   1 
ATOM   5758 C  CA  . LEU B 1 296 ? 124.405 119.920 158.914 1.00 23.33  ? 296 LEU B CA  1 
ATOM   5759 C  C   . LEU B 1 296 ? 123.220 120.196 159.829 1.00 23.33  ? 296 LEU B C   1 
ATOM   5760 O  O   . LEU B 1 296 ? 122.201 120.745 159.396 1.00 23.33  ? 296 LEU B O   1 
ATOM   5761 C  CB  . LEU B 1 296 ? 124.488 118.431 158.579 1.00 23.33  ? 296 LEU B CB  1 
ATOM   5762 C  CG  . LEU B 1 296 ? 123.236 117.795 157.977 1.00 23.33  ? 296 LEU B CG  1 
ATOM   5763 C  CD1 . LEU B 1 296 ? 123.101 118.157 156.513 1.00 23.33  ? 296 LEU B CD1 1 
ATOM   5764 C  CD2 . LEU B 1 296 ? 123.270 116.290 158.153 1.00 23.33  ? 296 LEU B CD2 1 
ATOM   5765 N  N   . LEU B 1 297 ? 123.338 119.826 161.106 1.00 22.23  ? 297 LEU B N   1 
ATOM   5766 C  CA  . LEU B 1 297 ? 122.229 120.032 162.035 1.00 22.23  ? 297 LEU B CA  1 
ATOM   5767 C  C   . LEU B 1 297 ? 121.938 121.515 162.234 1.00 22.23  ? 297 LEU B C   1 
ATOM   5768 O  O   . LEU B 1 297 ? 120.773 121.938 162.215 1.00 22.23  ? 297 LEU B O   1 
ATOM   5769 C  CB  . LEU B 1 297 ? 122.534 119.363 163.374 1.00 22.23  ? 297 LEU B CB  1 
ATOM   5770 C  CG  . LEU B 1 297 ? 122.613 117.837 163.374 1.00 22.23  ? 297 LEU B CG  1 
ATOM   5771 C  CD1 . LEU B 1 297 ? 123.057 117.330 164.735 1.00 22.23  ? 297 LEU B CD1 1 
ATOM   5772 C  CD2 . LEU B 1 297 ? 121.279 117.227 162.982 1.00 22.23  ? 297 LEU B CD2 1 
ATOM   5773 N  N   . LEU B 1 298 ? 122.984 122.324 162.421 1.00 19.80  ? 298 LEU B N   1 
ATOM   5774 C  CA  . LEU B 1 298 ? 122.778 123.749 162.647 1.00 19.80  ? 298 LEU B CA  1 
ATOM   5775 C  C   . LEU B 1 298 ? 122.213 124.431 161.409 1.00 19.80  ? 298 LEU B C   1 
ATOM   5776 O  O   . LEU B 1 298 ? 121.370 125.326 161.521 1.00 19.80  ? 298 LEU B O   1 
ATOM   5777 C  CB  . LEU B 1 298 ? 124.087 124.403 163.079 1.00 19.80  ? 298 LEU B CB  1 
ATOM   5778 C  CG  . LEU B 1 298 ? 124.537 124.060 164.498 1.00 19.80  ? 298 LEU B CG  1 
ATOM   5779 C  CD1 . LEU B 1 298 ? 125.847 124.753 164.831 1.00 19.80  ? 298 LEU B CD1 1 
ATOM   5780 C  CD2 . LEU B 1 298 ? 123.457 124.435 165.497 1.00 19.80  ? 298 LEU B CD2 1 
ATOM   5781 N  N   . SER B 1 299 ? 122.657 124.022 160.219 1.00 23.52  ? 299 SER B N   1 
ATOM   5782 C  CA  . SER B 1 299 ? 122.113 124.587 158.992 1.00 23.52  ? 299 SER B CA  1 
ATOM   5783 C  C   . SER B 1 299 ? 120.662 124.178 158.795 1.00 23.52  ? 299 SER B C   1 
ATOM   5784 O  O   . SER B 1 299 ? 119.853 124.973 158.307 1.00 23.52  ? 299 SER B O   1 
ATOM   5785 C  CB  . SER B 1 299 ? 122.963 124.162 157.796 1.00 23.52  ? 299 SER B CB  1 
ATOM   5786 O  OG  . SER B 1 299 ? 122.879 122.766 157.583 1.00 23.52  ? 299 SER B OG  1 
ATOM   5787 N  N   . TRP B 1 300 ? 120.308 122.944 159.164 1.00 28.02  ? 300 TRP B N   1 
ATOM   5788 C  CA  . TRP B 1 300 ? 118.907 122.542 159.104 1.00 28.02  ? 300 TRP B CA  1 
ATOM   5789 C  C   . TRP B 1 300 ? 118.054 123.398 160.028 1.00 28.02  ? 300 TRP B C   1 
ATOM   5790 O  O   . TRP B 1 300 ? 116.971 123.851 159.642 1.00 28.02  ? 300 TRP B O   1 
ATOM   5791 C  CB  . TRP B 1 300 ? 118.755 121.067 159.467 1.00 28.02  ? 300 TRP B CB  1 
ATOM   5792 C  CG  . TRP B 1 300 ? 117.347 120.706 159.827 1.00 28.02  ? 300 TRP B CG  1 
ATOM   5793 C  CD1 . TRP B 1 300 ? 116.258 120.755 159.010 1.00 28.02  ? 300 TRP B CD1 1 
ATOM   5794 C  CD2 . TRP B 1 300 ? 116.873 120.257 161.101 1.00 28.02  ? 300 TRP B CD2 1 
ATOM   5795 N  NE1 . TRP B 1 300 ? 115.135 120.358 159.693 1.00 28.02  ? 300 TRP B NE1 1 
ATOM   5796 C  CE2 . TRP B 1 300 ? 115.487 120.047 160.979 1.00 28.02  ? 300 TRP B CE2 1 
ATOM   5797 C  CE3 . TRP B 1 300 ? 117.487 120.008 162.331 1.00 28.02  ? 300 TRP B CE3 1 
ATOM   5798 C  CZ2 . TRP B 1 300 ? 114.704 119.602 162.040 1.00 28.02  ? 300 TRP B CZ2 1 
ATOM   5799 C  CZ3 . TRP B 1 300 ? 116.709 119.565 163.382 1.00 28.02  ? 300 TRP B CZ3 1 
ATOM   5800 C  CH2 . TRP B 1 300 ? 115.332 119.367 163.230 1.00 28.02  ? 300 TRP B CH2 1 
ATOM   5801 N  N   . ILE B 1 301 ? 118.531 123.637 161.252 1.00 26.35  ? 301 ILE B N   1 
ATOM   5802 C  CA  . ILE B 1 301 ? 117.784 124.480 162.184 1.00 26.35  ? 301 ILE B CA  1 
ATOM   5803 C  C   . ILE B 1 301 ? 117.658 125.899 161.641 1.00 26.35  ? 301 ILE B C   1 
ATOM   5804 O  O   . ILE B 1 301 ? 116.581 126.508 161.689 1.00 26.35  ? 301 ILE B O   1 
ATOM   5805 C  CB  . ILE B 1 301 ? 118.446 124.459 163.573 1.00 26.35  ? 301 ILE B CB  1 
ATOM   5806 C  CG1 . ILE B 1 301 ? 118.277 123.084 164.221 1.00 26.35  ? 301 ILE B CG1 1 
ATOM   5807 C  CG2 . ILE B 1 301 ? 117.866 125.547 164.460 1.00 26.35  ? 301 ILE B CG2 1 
ATOM   5808 C  CD1 . ILE B 1 301 ? 119.081 122.901 165.485 1.00 26.35  ? 301 ILE B CD1 1 
ATOM   5809 N  N   . TRP B 1 302 ? 118.754 126.445 161.110 1.00 23.27  ? 302 TRP B N   1 
ATOM   5810 C  CA  . TRP B 1 302 ? 118.735 127.807 160.588 1.00 23.27  ? 302 TRP B CA  1 
ATOM   5811 C  C   . TRP B 1 302 ? 117.783 127.937 159.406 1.00 23.27  ? 302 TRP B C   1 
ATOM   5812 O  O   . TRP B 1 302 ? 117.048 128.924 159.300 1.00 23.27  ? 302 TRP B O   1 
ATOM   5813 C  CB  . TRP B 1 302 ? 120.152 128.226 160.197 1.00 23.27  ? 302 TRP B CB  1 
ATOM   5814 C  CG  . TRP B 1 302 ? 120.220 129.395 159.268 1.00 23.27  ? 302 TRP B CG  1 
ATOM   5815 C  CD1 . TRP B 1 302 ? 120.637 129.385 157.971 1.00 23.27  ? 302 TRP B CD1 1 
ATOM   5816 C  CD2 . TRP B 1 302 ? 119.872 130.751 159.566 1.00 23.27  ? 302 TRP B CD2 1 
ATOM   5817 N  NE1 . TRP B 1 302 ? 120.566 130.649 157.441 1.00 23.27  ? 302 TRP B NE1 1 
ATOM   5818 C  CE2 . TRP B 1 302 ? 120.099 131.506 158.401 1.00 23.27  ? 302 TRP B CE2 1 
ATOM   5819 C  CE3 . TRP B 1 302 ? 119.387 131.400 160.705 1.00 23.27  ? 302 TRP B CE3 1 
ATOM   5820 C  CZ2 . TRP B 1 302 ? 119.859 132.875 158.341 1.00 23.27  ? 302 TRP B CZ2 1 
ATOM   5821 C  CZ3 . TRP B 1 302 ? 119.150 132.758 160.644 1.00 23.27  ? 302 TRP B CZ3 1 
ATOM   5822 C  CH2 . TRP B 1 302 ? 119.386 133.481 159.470 1.00 23.27  ? 302 TRP B CH2 1 
ATOM   5823 N  N   . LEU B 1 303 ? 117.782 126.952 158.507 1.00 25.33  ? 303 LEU B N   1 
ATOM   5824 C  CA  . LEU B 1 303 ? 116.889 126.999 157.355 1.00 25.33  ? 303 LEU B CA  1 
ATOM   5825 C  C   . LEU B 1 303 ? 115.434 126.824 157.771 1.00 25.33  ? 303 LEU B C   1 
ATOM   5826 O  O   . LEU B 1 303 ? 114.544 127.483 157.224 1.00 25.33  ? 303 LEU B O   1 
ATOM   5827 C  CB  . LEU B 1 303 ? 117.295 125.933 156.341 1.00 25.33  ? 303 LEU B CB  1 
ATOM   5828 C  CG  . LEU B 1 303 ? 118.522 126.266 155.492 1.00 25.33  ? 303 LEU B CG  1 
ATOM   5829 C  CD1 . LEU B 1 303 ? 118.927 125.076 154.645 1.00 25.33  ? 303 LEU B CD1 1 
ATOM   5830 C  CD2 . LEU B 1 303 ? 118.243 127.471 154.618 1.00 25.33  ? 303 LEU B CD2 1 
ATOM   5831 N  N   . GLN B 1 304 ? 115.170 125.939 158.736 1.00 33.94  ? 304 GLN B N   1 
ATOM   5832 C  CA  . GLN B 1 304 ? 113.813 125.765 159.236 1.00 33.94  ? 304 GLN B CA  1 
ATOM   5833 C  C   . GLN B 1 304 ? 113.320 126.985 160.000 1.00 33.94  ? 304 GLN B C   1 
ATOM   5834 O  O   . GLN B 1 304 ? 112.106 127.173 160.126 1.00 33.94  ? 304 GLN B O   1 
ATOM   5835 C  CB  . GLN B 1 304 ? 113.740 124.526 160.132 1.00 33.94  ? 304 GLN B CB  1 
ATOM   5836 C  CG  . GLN B 1 304 ? 112.354 123.886 160.296 1.00 33.94  ? 304 GLN B CG  1 
ATOM   5837 C  CD  . GLN B 1 304 ? 111.650 123.524 158.992 1.00 33.94  ? 304 GLN B CD  1 
ATOM   5838 O  OE1 . GLN B 1 304 ? 112.165 123.734 157.896 1.00 33.94  ? 304 GLN B OE1 1 
ATOM   5839 N  NE2 . GLN B 1 304 ? 110.448 122.974 159.118 1.00 33.94  ? 304 GLN B NE2 1 
ATOM   5840 N  N   . TRP B 1 305 ? 114.228 127.804 160.531 1.00 32.73  ? 305 TRP B N   1 
ATOM   5841 C  CA  . TRP B 1 305 ? 113.801 129.032 161.191 1.00 32.73  ? 305 TRP B CA  1 
ATOM   5842 C  C   . TRP B 1 305 ? 113.608 130.169 160.196 1.00 32.73  ? 305 TRP B C   1 
ATOM   5843 O  O   . TRP B 1 305 ? 112.653 130.944 160.317 1.00 32.73  ? 305 TRP B O   1 
ATOM   5844 C  CB  . TRP B 1 305 ? 114.812 129.439 162.261 1.00 32.73  ? 305 TRP B CB  1 
ATOM   5845 C  CG  . TRP B 1 305 ? 114.409 130.672 163.009 1.00 32.73  ? 305 TRP B CG  1 
ATOM   5846 C  CD1 . TRP B 1 305 ? 113.669 130.730 164.152 1.00 32.73  ? 305 TRP B CD1 1 
ATOM   5847 C  CD2 . TRP B 1 305 ? 114.718 132.026 162.662 1.00 32.73  ? 305 TRP B CD2 1 
ATOM   5848 N  NE1 . TRP B 1 305 ? 113.501 132.036 164.541 1.00 32.73  ? 305 TRP B NE1 1 
ATOM   5849 C  CE2 . TRP B 1 305 ? 114.135 132.851 163.642 1.00 32.73  ? 305 TRP B CE2 1 
ATOM   5850 C  CE3 . TRP B 1 305 ? 115.433 132.621 161.618 1.00 32.73  ? 305 TRP B CE3 1 
ATOM   5851 C  CZ2 . TRP B 1 305 ? 114.245 134.238 163.610 1.00 32.73  ? 305 TRP B CZ2 1 
ATOM   5852 C  CZ3 . TRP B 1 305 ? 115.539 133.998 161.589 1.00 32.73  ? 305 TRP B CZ3 1 
ATOM   5853 C  CH2 . TRP B 1 305 ? 114.949 134.790 162.577 1.00 32.73  ? 305 TRP B CH2 1 
ATOM   5854 N  N   . LEU B 1 306 ? 114.506 130.291 159.217 1.00 28.31  ? 306 LEU B N   1 
ATOM   5855 C  CA  . LEU B 1 306 ? 114.422 131.389 158.259 1.00 28.31  ? 306 LEU B CA  1 
ATOM   5856 C  C   . LEU B 1 306 ? 113.177 131.268 157.390 1.00 28.31  ? 306 LEU B C   1 
ATOM   5857 O  O   . LEU B 1 306 ? 112.409 132.227 157.249 1.00 28.31  ? 306 LEU B O   1 
ATOM   5858 C  CB  . LEU B 1 306 ? 115.683 131.419 157.396 1.00 28.31  ? 306 LEU B CB  1 
ATOM   5859 C  CG  . LEU B 1 306 ? 115.852 132.616 156.466 1.00 28.31  ? 306 LEU B CG  1 
ATOM   5860 C  CD1 . LEU B 1 306 ? 115.939 133.898 157.269 1.00 28.31  ? 306 LEU B CD1 1 
ATOM   5861 C  CD2 . LEU B 1 306 ? 117.084 132.437 155.602 1.00 28.31  ? 306 LEU B CD2 1 
ATOM   5862 N  N   . PHE B 1 307 ? 112.961 130.096 156.804 1.00 30.27  ? 307 PHE B N   1 
ATOM   5863 C  CA  . PHE B 1 307 ? 111.752 129.796 156.054 1.00 30.27  ? 307 PHE B CA  1 
ATOM   5864 C  C   . PHE B 1 307 ? 110.827 128.963 156.927 1.00 30.27  ? 307 PHE B C   1 
ATOM   5865 O  O   . PHE B 1 307 ? 111.291 128.143 157.724 1.00 30.27  ? 307 PHE B O   1 
ATOM   5866 C  CB  . PHE B 1 307 ? 112.076 129.044 154.763 1.00 30.27  ? 307 PHE B CB  1 
ATOM   5867 C  CG  . PHE B 1 307 ? 113.132 129.702 153.929 1.00 30.27  ? 307 PHE B CG  1 
ATOM   5868 C  CD1 . PHE B 1 307 ? 112.797 130.679 153.010 1.00 30.27  ? 307 PHE B CD1 1 
ATOM   5869 C  CD2 . PHE B 1 307 ? 114.461 129.349 154.066 1.00 30.27  ? 307 PHE B CD2 1 
ATOM   5870 C  CE1 . PHE B 1 307 ? 113.767 131.287 152.243 1.00 30.27  ? 307 PHE B CE1 1 
ATOM   5871 C  CE2 . PHE B 1 307 ? 115.433 129.956 153.304 1.00 30.27  ? 307 PHE B CE2 1 
ATOM   5872 C  CZ  . PHE B 1 307 ? 115.086 130.926 152.391 1.00 30.27  ? 307 PHE B CZ  1 
ATOM   5873 N  N   . LEU B 1 308 ? 109.520 129.190 156.785 1.00 36.58  ? 308 LEU B N   1 
ATOM   5874 C  CA  . LEU B 1 308 ? 108.515 128.526 157.609 1.00 36.58  ? 308 LEU B CA  1 
ATOM   5875 C  C   . LEU B 1 308 ? 108.708 128.894 159.075 1.00 36.58  ? 308 LEU B C   1 
ATOM   5876 O  O   . LEU B 1 308 ? 109.390 129.874 159.392 1.00 36.58  ? 308 LEU B O   1 
ATOM   5877 C  CB  . LEU B 1 308 ? 108.565 127.003 157.431 1.00 36.58  ? 308 LEU B CB  1 
ATOM   5878 C  CG  . LEU B 1 308 ? 107.988 126.389 156.154 1.00 36.58  ? 308 LEU B CG  1 
ATOM   5879 C  CD1 . LEU B 1 308 ? 108.961 126.518 154.995 1.00 36.58  ? 308 LEU B CD1 1 
ATOM   5880 C  CD2 . LEU B 1 308 ? 107.625 124.931 156.384 1.00 36.58  ? 308 LEU B CD2 1 
ATOM   5881 N  N   . GLY B 1 309 ? 108.108 128.122 159.974 1.00 45.20  ? 309 GLY B N   1 
ATOM   5882 C  CA  . GLY B 1 309 ? 108.220 128.366 161.398 1.00 45.20  ? 309 GLY B CA  1 
ATOM   5883 C  C   . GLY B 1 309 ? 108.873 127.195 162.105 1.00 45.20  ? 309 GLY B C   1 
ATOM   5884 O  O   . GLY B 1 309 ? 108.853 126.065 161.615 1.00 45.20  ? 309 GLY B O   1 
ATOM   5885 N  N   . PHE B 1 310 ? 109.459 127.477 163.266 1.00 60.91  ? 310 PHE B N   1 
ATOM   5886 C  CA  . PHE B 1 310 ? 110.095 126.461 164.095 1.00 60.91  ? 310 PHE B CA  1 
ATOM   5887 C  C   . PHE B 1 310 ? 109.425 126.459 165.461 1.00 60.91  ? 310 PHE B C   1 
ATOM   5888 O  O   . PHE B 1 310 ? 109.416 127.483 166.152 1.00 60.91  ? 310 PHE B O   1 
ATOM   5889 C  CB  . PHE B 1 310 ? 111.597 126.722 164.233 1.00 60.91  ? 310 PHE B CB  1 
ATOM   5890 C  CG  . PHE B 1 310 ? 112.399 125.494 164.557 1.00 60.91  ? 310 PHE B CG  1 
ATOM   5891 C  CD1 . PHE B 1 310 ? 112.301 124.890 165.799 1.00 60.91  ? 310 PHE B CD1 1 
ATOM   5892 C  CD2 . PHE B 1 310 ? 113.256 124.947 163.619 1.00 60.91  ? 310 PHE B CD2 1 
ATOM   5893 C  CE1 . PHE B 1 310 ? 113.038 123.761 166.095 1.00 60.91  ? 310 PHE B CE1 1 
ATOM   5894 C  CE2 . PHE B 1 310 ? 113.996 123.820 163.909 1.00 60.91  ? 310 PHE B CE2 1 
ATOM   5895 C  CZ  . PHE B 1 310 ? 113.887 123.226 165.148 1.00 60.91  ? 310 PHE B CZ  1 
ATOM   5896 N  N   . ASN B 1 311 ? 108.869 125.313 165.847 1.00 88.04  ? 311 ASN B N   1 
ATOM   5897 C  CA  . ASN B 1 311 ? 108.253 125.138 167.156 1.00 88.04  ? 311 ASN B CA  1 
ATOM   5898 C  C   . ASN B 1 311 ? 108.832 123.886 167.796 1.00 88.04  ? 311 ASN B C   1 
ATOM   5899 O  O   . ASN B 1 311 ? 108.739 122.796 167.223 1.00 88.04  ? 311 ASN B O   1 
ATOM   5900 C  CB  . ASN B 1 311 ? 106.729 125.034 167.044 1.00 88.04  ? 311 ASN B CB  1 
ATOM   5901 C  CG  . ASN B 1 311 ? 106.023 125.383 168.341 1.00 88.04  ? 311 ASN B CG  1 
ATOM   5902 O  OD1 . ASN B 1 311 ? 106.558 125.173 169.429 1.00 88.04  ? 311 ASN B OD1 1 
ATOM   5903 N  ND2 . ASN B 1 311 ? 104.815 125.922 168.229 1.00 88.04  ? 311 ASN B ND2 1 
ATOM   5904 N  N   . PHE B 1 312 ? 109.419 124.044 168.984 1.00 94.51  ? 312 PHE B N   1 
ATOM   5905 C  CA  . PHE B 1 312 ? 110.081 122.919 169.638 1.00 94.51  ? 312 PHE B CA  1 
ATOM   5906 C  C   . PHE B 1 312 ? 109.089 121.821 170.000 1.00 94.51  ? 312 PHE B C   1 
ATOM   5907 O  O   . PHE B 1 312 ? 109.390 120.630 169.853 1.00 94.51  ? 312 PHE B O   1 
ATOM   5908 C  CB  . PHE B 1 312 ? 110.826 123.404 170.881 1.00 94.51  ? 312 PHE B CB  1 
ATOM   5909 C  CG  . PHE B 1 312 ? 111.835 124.481 170.601 1.00 94.51  ? 312 PHE B CG  1 
ATOM   5910 C  CD1 . PHE B 1 312 ? 113.126 124.158 170.218 1.00 94.51  ? 312 PHE B CD1 1 
ATOM   5911 C  CD2 . PHE B 1 312 ? 111.492 125.818 170.720 1.00 94.51  ? 312 PHE B CD2 1 
ATOM   5912 C  CE1 . PHE B 1 312 ? 114.056 125.146 169.959 1.00 94.51  ? 312 PHE B CE1 1 
ATOM   5913 C  CE2 . PHE B 1 312 ? 112.418 126.812 170.463 1.00 94.51  ? 312 PHE B CE2 1 
ATOM   5914 C  CZ  . PHE B 1 312 ? 113.701 126.475 170.081 1.00 94.51  ? 312 PHE B CZ  1 
ATOM   5915 N  N   . LYS B 1 313 ? 107.901 122.199 170.476 1.00 101.02 ? 313 LYS B N   1 
ATOM   5916 C  CA  . LYS B 1 313 ? 106.922 121.201 170.896 1.00 101.02 ? 313 LYS B CA  1 
ATOM   5917 C  C   . LYS B 1 313 ? 106.332 120.442 169.714 1.00 101.02 ? 313 LYS B C   1 
ATOM   5918 O  O   . LYS B 1 313 ? 105.900 119.295 169.874 1.00 101.02 ? 313 LYS B O   1 
ATOM   5919 C  CB  . LYS B 1 313 ? 105.809 121.864 171.706 1.00 101.02 ? 313 LYS B CB  1 
ATOM   5920 C  CG  . LYS B 1 313 ? 105.936 121.668 173.207 1.00 101.02 ? 313 LYS B CG  1 
ATOM   5921 C  CD  . LYS B 1 313 ? 105.986 120.191 173.563 1.00 101.02 ? 313 LYS B CD  1 
ATOM   5922 C  CE  . LYS B 1 313 ? 106.092 119.986 175.065 1.00 101.02 ? 313 LYS B CE  1 
ATOM   5923 N  NZ  . LYS B 1 313 ? 106.060 118.542 175.430 1.00 101.02 ? 313 LYS B NZ  1 
ATOM   5924 N  N   . GLU B 1 314 ? 106.296 121.058 168.530 1.00 97.79  ? 314 GLU B N   1 
ATOM   5925 C  CA  . GLU B 1 314 ? 105.704 120.394 167.372 1.00 97.79  ? 314 GLU B CA  1 
ATOM   5926 C  C   . GLU B 1 314 ? 106.506 119.163 166.967 1.00 97.79  ? 314 GLU B C   1 
ATOM   5927 O  O   . GLU B 1 314 ? 105.942 118.083 166.760 1.00 97.79  ? 314 GLU B O   1 
ATOM   5928 C  CB  . GLU B 1 314 ? 105.590 121.376 166.207 1.00 97.79  ? 314 GLU B CB  1 
ATOM   5929 C  CG  . GLU B 1 314 ? 104.420 122.333 166.330 1.00 97.79  ? 314 GLU B CG  1 
ATOM   5930 C  CD  . GLU B 1 314 ? 103.155 121.641 166.797 1.00 97.79  ? 314 GLU B CD  1 
ATOM   5931 O  OE1 . GLU B 1 314 ? 102.652 120.762 166.065 1.00 97.79  ? 314 GLU B OE1 1 
ATOM   5932 O  OE2 . GLU B 1 314 ? 102.664 121.972 167.896 1.00 97.79  ? 314 GLU B OE2 1 
ATOM   5933 N  N   . MET B 1 315 ? 107.827 119.306 166.847 1.00 92.17  ? 315 MET B N   1 
ATOM   5934 C  CA  . MET B 1 315 ? 108.657 118.157 166.500 1.00 92.17  ? 315 MET B CA  1 
ATOM   5935 C  C   . MET B 1 315 ? 108.825 117.213 167.686 1.00 92.17  ? 315 MET B C   1 
ATOM   5936 O  O   . MET B 1 315 ? 108.880 115.990 167.510 1.00 92.17  ? 315 MET B O   1 
ATOM   5937 C  CB  . MET B 1 315 ? 110.016 118.624 165.978 1.00 92.17  ? 315 MET B CB  1 
ATOM   5938 C  CG  . MET B 1 315 ? 109.992 119.092 164.530 1.00 92.17  ? 315 MET B CG  1 
ATOM   5939 S  SD  . MET B 1 315 ? 109.005 120.574 164.252 1.00 92.17  ? 315 MET B SD  1 
ATOM   5940 C  CE  . MET B 1 315 ? 110.222 121.847 164.565 1.00 92.17  ? 315 MET B CE  1 
ATOM   5941 N  N   . PHE B 1 316 ? 108.904 117.756 168.895 1.00 105.70 ? 316 PHE B N   1 
ATOM   5942 C  CA  . PHE B 1 316 ? 109.046 116.932 170.089 1.00 105.70 ? 316 PHE B CA  1 
ATOM   5943 C  C   . PHE B 1 316 ? 107.690 116.417 170.559 1.00 105.70 ? 316 PHE B C   1 
ATOM   5944 O  O   . PHE B 1 316 ? 106.971 115.759 169.807 1.00 105.70 ? 316 PHE B O   1 
ATOM   5945 C  CB  . PHE B 1 316 ? 109.729 117.720 171.208 1.00 105.70 ? 316 PHE B CB  1 
ATOM   5946 C  CG  . PHE B 1 316 ? 111.228 117.646 171.173 1.00 105.70 ? 316 PHE B CG  1 
ATOM   5947 C  CD1 . PHE B 1 316 ? 111.937 118.186 170.112 1.00 105.70 ? 316 PHE B CD1 1 
ATOM   5948 C  CD2 . PHE B 1 316 ? 111.929 117.036 172.199 1.00 105.70 ? 316 PHE B CD2 1 
ATOM   5949 C  CE1 . PHE B 1 316 ? 113.317 118.119 170.076 1.00 105.70 ? 316 PHE B CE1 1 
ATOM   5950 C  CE2 . PHE B 1 316 ? 113.310 116.966 172.169 1.00 105.70 ? 316 PHE B CE2 1 
ATOM   5951 C  CZ  . PHE B 1 316 ? 114.004 117.508 171.106 1.00 105.70 ? 316 PHE B CZ  1 
ATOM   5952 N  N   . THR B 1 323 ? 96.278  115.541 163.568 1.00 86.55  ? 323 THR B N   1 
ATOM   5953 C  CA  . THR B 1 323 ? 95.171  116.357 163.084 1.00 86.55  ? 323 THR B CA  1 
ATOM   5954 C  C   . THR B 1 323 ? 94.536  115.728 161.846 1.00 86.55  ? 323 THR B C   1 
ATOM   5955 O  O   . THR B 1 323 ? 95.193  114.992 161.108 1.00 86.55  ? 323 THR B O   1 
ATOM   5956 C  CB  . THR B 1 323 ? 95.628  117.791 162.750 1.00 86.55  ? 323 THR B CB  1 
ATOM   5957 O  OG1 . THR B 1 323 ? 94.495  118.573 162.352 1.00 86.55  ? 323 THR B OG1 1 
ATOM   5958 C  CG2 . THR B 1 323 ? 96.662  117.781 161.626 1.00 86.55  ? 323 THR B CG2 1 
ATOM   5959 N  N   . VAL B 1 324 ? 93.254  116.031 161.625 1.00 85.33  ? 324 VAL B N   1 
ATOM   5960 C  CA  . VAL B 1 324 ? 92.509  115.424 160.528 1.00 85.33  ? 324 VAL B CA  1 
ATOM   5961 C  C   . VAL B 1 324 ? 93.078  115.820 159.174 1.00 85.33  ? 324 VAL B C   1 
ATOM   5962 O  O   . VAL B 1 324 ? 92.884  115.096 158.188 1.00 85.33  ? 324 VAL B O   1 
ATOM   5963 C  CB  . VAL B 1 324 ? 91.016  115.795 160.629 1.00 85.33  ? 324 VAL B CB  1 
ATOM   5964 C  CG1 . VAL B 1 324 ? 90.784  117.233 160.186 1.00 85.33  ? 324 VAL B CG1 1 
ATOM   5965 C  CG2 . VAL B 1 324 ? 90.160  114.827 159.825 1.00 85.33  ? 324 VAL B CG2 1 
ATOM   5966 N  N   . GLN B 1 325 ? 93.790  116.949 159.101 1.00 85.09  ? 325 GLN B N   1 
ATOM   5967 C  CA  . GLN B 1 325 ? 94.433  117.345 157.853 1.00 85.09  ? 325 GLN B CA  1 
ATOM   5968 C  C   . GLN B 1 325 ? 95.467  116.318 157.417 1.00 85.09  ? 325 GLN B C   1 
ATOM   5969 O  O   . GLN B 1 325 ? 95.589  116.018 156.224 1.00 85.09  ? 325 GLN B O   1 
ATOM   5970 C  CB  . GLN B 1 325 ? 95.084  118.720 158.005 1.00 85.09  ? 325 GLN B CB  1 
ATOM   5971 C  CG  . GLN B 1 325 ? 94.101  119.877 158.034 1.00 85.09  ? 325 GLN B CG  1 
ATOM   5972 C  CD  . GLN B 1 325 ? 93.549  120.142 159.420 1.00 85.09  ? 325 GLN B CD  1 
ATOM   5973 O  OE1 . GLN B 1 325 ? 93.904  119.463 160.383 1.00 85.09  ? 325 GLN B OE1 1 
ATOM   5974 N  NE2 . GLN B 1 325 ? 92.671  121.134 159.527 1.00 85.09  ? 325 GLN B NE2 1 
ATOM   5975 N  N   . GLN B 1 326 ? 96.234  115.781 158.367 1.00 83.75  ? 326 GLN B N   1 
ATOM   5976 C  CA  . GLN B 1 326 ? 97.235  114.778 158.023 1.00 83.75  ? 326 GLN B CA  1 
ATOM   5977 C  C   . GLN B 1 326 ? 96.590  113.513 157.470 1.00 83.75  ? 326 GLN B C   1 
ATOM   5978 O  O   . GLN B 1 326 ? 97.079  112.939 156.491 1.00 83.75  ? 326 GLN B O   1 
ATOM   5979 C  CB  . GLN B 1 326 ? 98.104  114.460 159.239 1.00 83.75  ? 326 GLN B CB  1 
ATOM   5980 C  CG  . GLN B 1 326 ? 99.061  115.581 159.615 1.00 83.75  ? 326 GLN B CG  1 
ATOM   5981 C  CD  . GLN B 1 326 ? 99.781  115.324 160.922 1.00 83.75  ? 326 GLN B CD  1 
ATOM   5982 O  OE1 . GLN B 1 326 ? 99.530  114.326 161.597 1.00 83.75  ? 326 GLN B OE1 1 
ATOM   5983 N  NE2 . GLN B 1 326 ? 100.686 116.225 161.285 1.00 83.75  ? 326 GLN B NE2 1 
ATOM   5984 N  N   . LYS B 1 327 ? 95.487  113.062 158.077 1.00 78.36  ? 327 LYS B N   1 
ATOM   5985 C  CA  . LYS B 1 327 ? 94.783  111.902 157.534 1.00 78.36  ? 327 LYS B CA  1 
ATOM   5986 C  C   . LYS B 1 327 ? 94.215  112.184 156.149 1.00 78.36  ? 327 LYS B C   1 
ATOM   5987 O  O   . LYS B 1 327 ? 94.267  111.319 155.267 1.00 78.36  ? 327 LYS B O   1 
ATOM   5988 C  CB  . LYS B 1 327 ? 93.671  111.433 158.475 1.00 78.36  ? 327 LYS B CB  1 
ATOM   5989 C  CG  . LYS B 1 327 ? 94.134  110.518 159.603 1.00 78.36  ? 327 LYS B CG  1 
ATOM   5990 C  CD  . LYS B 1 327 ? 94.892  111.210 160.718 1.00 78.36  ? 327 LYS B CD  1 
ATOM   5991 C  CE  . LYS B 1 327 ? 93.979  112.108 161.530 1.00 78.36  ? 327 LYS B CE  1 
ATOM   5992 N  NZ  . LYS B 1 327 ? 94.704  112.739 162.669 1.00 78.36  ? 327 LYS B NZ  1 
ATOM   5993 N  N   . ALA B 1 328 ? 93.647  113.374 155.941 1.00 73.04  ? 328 ALA B N   1 
ATOM   5994 C  CA  . ALA B 1 328 ? 93.120  113.706 154.620 1.00 73.04  ? 328 ALA B CA  1 
ATOM   5995 C  C   . ALA B 1 328 ? 94.228  113.717 153.573 1.00 73.04  ? 328 ALA B C   1 
ATOM   5996 O  O   . ALA B 1 328 ? 94.053  113.195 152.463 1.00 73.04  ? 328 ALA B O   1 
ATOM   5997 C  CB  . ALA B 1 328 ? 92.404  115.055 154.663 1.00 73.04  ? 328 ALA B CB  1 
ATOM   5998 N  N   . CYS B 1 329 ? 95.379  114.304 153.910 1.00 68.78  ? 329 CYS B N   1 
ATOM   5999 C  CA  . CYS B 1 329 ? 96.506  114.323 152.984 1.00 68.78  ? 329 CYS B CA  1 
ATOM   6000 C  C   . CYS B 1 329 ? 97.004  112.915 152.693 1.00 68.78  ? 329 CYS B C   1 
ATOM   6001 O  O   . CYS B 1 329 ? 97.331  112.593 151.546 1.00 68.78  ? 329 CYS B O   1 
ATOM   6002 C  CB  . CYS B 1 329 ? 97.637  115.181 153.548 1.00 68.78  ? 329 CYS B CB  1 
ATOM   6003 S  SG  . CYS B 1 329 ? 97.449  116.960 153.280 1.00 68.78  ? 329 CYS B SG  1 
ATOM   6004 N  N   . ALA B 1 330 ? 97.075  112.064 153.719 1.00 62.73  ? 330 ALA B N   1 
ATOM   6005 C  CA  . ALA B 1 330 ? 97.501  110.686 153.505 1.00 62.73  ? 330 ALA B CA  1 
ATOM   6006 C  C   . ALA B 1 330 ? 96.529  109.946 152.598 1.00 62.73  ? 330 ALA B C   1 
ATOM   6007 O  O   . ALA B 1 330 ? 96.946  109.179 151.722 1.00 62.73  ? 330 ALA B O   1 
ATOM   6008 C  CB  . ALA B 1 330 ? 97.642  109.965 154.845 1.00 62.73  ? 330 ALA B CB  1 
ATOM   6009 N  N   . GLU B 1 331 ? 95.226  110.161 152.793 1.00 61.89  ? 331 GLU B N   1 
ATOM   6010 C  CA  . GLU B 1 331 ? 94.238  109.521 151.931 1.00 61.89  ? 331 GLU B CA  1 
ATOM   6011 C  C   . GLU B 1 331 ? 94.379  109.991 150.490 1.00 61.89  ? 331 GLU B C   1 
ATOM   6012 O  O   . GLU B 1 331 ? 94.307  109.182 149.558 1.00 61.89  ? 331 GLU B O   1 
ATOM   6013 C  CB  . GLU B 1 331 ? 92.828  109.795 152.452 1.00 61.89  ? 331 GLU B CB  1 
ATOM   6014 C  CG  . GLU B 1 331 ? 92.483  109.041 153.725 1.00 61.89  ? 331 GLU B CG  1 
ATOM   6015 C  CD  . GLU B 1 331 ? 91.091  109.364 154.229 1.00 61.89  ? 331 GLU B CD  1 
ATOM   6016 O  OE1 . GLU B 1 331 ? 90.354  110.082 153.521 1.00 61.89  ? 331 GLU B OE1 1 
ATOM   6017 O  OE2 . GLU B 1 331 ? 90.733  108.900 155.332 1.00 61.89  ? 331 GLU B OE2 1 
ATOM   6018 N  N   . VAL B 1 332 ? 94.587  111.293 150.287 1.00 55.70  ? 332 VAL B N   1 
ATOM   6019 C  CA  . VAL B 1 332 ? 94.757  111.812 148.931 1.00 55.70  ? 332 VAL B CA  1 
ATOM   6020 C  C   . VAL B 1 332 ? 96.010  111.229 148.288 1.00 55.70  ? 332 VAL B C   1 
ATOM   6021 O  O   . VAL B 1 332 ? 96.004  110.851 147.109 1.00 55.70  ? 332 VAL B O   1 
ATOM   6022 C  CB  . VAL B 1 332 ? 94.786  113.351 148.945 1.00 55.70  ? 332 VAL B CB  1 
ATOM   6023 C  CG1 . VAL B 1 332 ? 95.142  113.890 147.571 1.00 55.70  ? 332 VAL B CG1 1 
ATOM   6024 C  CG2 . VAL B 1 332 ? 93.440  113.898 149.392 1.00 55.70  ? 332 VAL B CG2 1 
ATOM   6025 N  N   . ILE B 1 333 ? 97.104  111.148 149.050 1.00 49.66  ? 333 ILE B N   1 
ATOM   6026 C  CA  . ILE B 1 333 ? 98.346  110.594 148.518 1.00 49.66  ? 333 ILE B CA  1 
ATOM   6027 C  C   . ILE B 1 333 ? 98.159  109.131 148.137 1.00 49.66  ? 333 ILE B C   1 
ATOM   6028 O  O   . ILE B 1 333 ? 98.616  108.687 147.077 1.00 49.66  ? 333 ILE B O   1 
ATOM   6029 C  CB  . ILE B 1 333 ? 99.489  110.774 149.533 1.00 49.66  ? 333 ILE B CB  1 
ATOM   6030 C  CG1 . ILE B 1 333 ? 99.878  112.248 149.648 1.00 49.66  ? 333 ILE B CG1 1 
ATOM   6031 C  CG2 . ILE B 1 333 ? 100.691 109.943 149.133 1.00 49.66  ? 333 ILE B CG2 1 
ATOM   6032 C  CD1 . ILE B 1 333 ? 100.246 112.887 148.333 1.00 49.66  ? 333 ILE B CD1 1 
ATOM   6033 N  N   . LYS B 1 334 ? 97.485  108.359 148.993 1.00 49.78  ? 334 LYS B N   1 
ATOM   6034 C  CA  . LYS B 1 334 ? 97.232  106.956 148.683 1.00 49.78  ? 334 LYS B CA  1 
ATOM   6035 C  C   . LYS B 1 334 ? 96.359  106.814 147.442 1.00 49.78  ? 334 LYS B C   1 
ATOM   6036 O  O   . LYS B 1 334 ? 96.600  105.939 146.602 1.00 49.78  ? 334 LYS B O   1 
ATOM   6037 C  CB  . LYS B 1 334 ? 96.577  106.264 149.877 1.00 49.78  ? 334 LYS B CB  1 
ATOM   6038 C  CG  . LYS B 1 334 ? 97.557  105.690 150.882 1.00 49.78  ? 334 LYS B CG  1 
ATOM   6039 C  CD  . LYS B 1 334 ? 96.940  105.615 152.270 1.00 49.78  ? 334 LYS B CD  1 
ATOM   6040 C  CE  . LYS B 1 334 ? 95.510  105.099 152.216 1.00 49.78  ? 334 LYS B CE  1 
ATOM   6041 N  NZ  . LYS B 1 334 ? 94.712  105.543 153.391 1.00 49.78  ? 334 LYS B NZ  1 
ATOM   6042 N  N   . GLN B 1 335 ? 95.335  107.660 147.315 1.00 51.38  ? 335 GLN B N   1 
ATOM   6043 C  CA  . GLN B 1 335 ? 94.473  107.602 146.140 1.00 51.38  ? 335 GLN B CA  1 
ATOM   6044 C  C   . GLN B 1 335 ? 95.258  107.906 144.872 1.00 51.38  ? 335 GLN B C   1 
ATOM   6045 O  O   . GLN B 1 335 ? 95.091  107.230 143.851 1.00 51.38  ? 335 GLN B O   1 
ATOM   6046 C  CB  . GLN B 1 335 ? 93.304  108.574 146.296 1.00 51.38  ? 335 GLN B CB  1 
ATOM   6047 C  CG  . GLN B 1 335 ? 92.286  108.165 147.351 1.00 51.38  ? 335 GLN B CG  1 
ATOM   6048 C  CD  . GLN B 1 335 ? 91.188  107.283 146.797 1.00 51.38  ? 335 GLN B CD  1 
ATOM   6049 O  OE1 . GLN B 1 335 ? 91.125  106.090 147.095 1.00 51.38  ? 335 GLN B OE1 1 
ATOM   6050 N  NE2 . GLN B 1 335 ? 90.311  107.866 145.988 1.00 51.38  ? 335 GLN B NE2 1 
ATOM   6051 N  N   . GLU B 1 336 ? 96.130  108.915 144.920 1.00 46.07  ? 336 GLU B N   1 
ATOM   6052 C  CA  . GLU B 1 336 ? 96.940  109.241 143.750 1.00 46.07  ? 336 GLU B CA  1 
ATOM   6053 C  C   . GLU B 1 336 ? 97.899  108.106 143.408 1.00 46.07  ? 336 GLU B C   1 
ATOM   6054 O  O   . GLU B 1 336 ? 98.084  107.768 142.231 1.00 46.07  ? 336 GLU B O   1 
ATOM   6055 C  CB  . GLU B 1 336 ? 97.704  110.542 143.991 1.00 46.07  ? 336 GLU B CB  1 
ATOM   6056 C  CG  . GLU B 1 336 ? 98.244  111.184 142.728 1.00 46.07  ? 336 GLU B CG  1 
ATOM   6057 C  CD  . GLU B 1 336 ? 97.147  111.742 141.844 1.00 46.07  ? 336 GLU B CD  1 
ATOM   6058 O  OE1 . GLU B 1 336 ? 96.088  112.129 142.381 1.00 46.07  ? 336 GLU B OE1 1 
ATOM   6059 O  OE2 . GLU B 1 336 ? 97.345  111.797 140.613 1.00 46.07  ? 336 GLU B OE2 1 
ATOM   6060 N  N   . TYR B 1 337 ? 98.513  107.499 144.428 1.00 42.00  ? 337 TYR B N   1 
ATOM   6061 C  CA  . TYR B 1 337 ? 99.429  106.389 144.188 1.00 42.00  ? 337 TYR B CA  1 
ATOM   6062 C  C   . TYR B 1 337 ? 98.708  105.203 143.561 1.00 42.00  ? 337 TYR B C   1 
ATOM   6063 O  O   . TYR B 1 337 ? 99.243  104.548 142.659 1.00 42.00  ? 337 TYR B O   1 
ATOM   6064 C  CB  . TYR B 1 337 ? 100.107 105.976 145.492 1.00 42.00  ? 337 TYR B CB  1 
ATOM   6065 C  CG  . TYR B 1 337 ? 101.293 105.062 145.299 1.00 42.00  ? 337 TYR B CG  1 
ATOM   6066 C  CD1 . TYR B 1 337 ? 102.514 105.560 144.870 1.00 42.00  ? 337 TYR B CD1 1 
ATOM   6067 C  CD2 . TYR B 1 337 ? 101.191 103.701 145.546 1.00 42.00  ? 337 TYR B CD2 1 
ATOM   6068 C  CE1 . TYR B 1 337 ? 103.601 104.728 144.693 1.00 42.00  ? 337 TYR B CE1 1 
ATOM   6069 C  CE2 . TYR B 1 337 ? 102.272 102.861 145.371 1.00 42.00  ? 337 TYR B CE2 1 
ATOM   6070 C  CZ  . TYR B 1 337 ? 103.475 103.380 144.944 1.00 42.00  ? 337 TYR B CZ  1 
ATOM   6071 O  OH  . TYR B 1 337 ? 104.555 102.548 144.769 1.00 42.00  ? 337 TYR B OH  1 
ATOM   6072 N  N   . GLN B 1 338 ? 97.495  104.905 144.031 1.00 44.15  ? 338 GLN B N   1 
ATOM   6073 C  CA  . GLN B 1 338 ? 96.699  103.861 143.396 1.00 44.15  ? 338 GLN B CA  1 
ATOM   6074 C  C   . GLN B 1 338 ? 96.319  104.240 141.970 1.00 44.15  ? 338 GLN B C   1 
ATOM   6075 O  O   . GLN B 1 338 ? 96.259  103.370 141.094 1.00 44.15  ? 338 GLN B O   1 
ATOM   6076 C  CB  . GLN B 1 338 ? 95.445  103.572 144.221 1.00 44.15  ? 338 GLN B CB  1 
ATOM   6077 C  CG  . GLN B 1 338 ? 95.694  102.710 145.447 1.00 44.15  ? 338 GLN B CG  1 
ATOM   6078 C  CD  . GLN B 1 338 ? 95.009  103.250 146.686 1.00 44.15  ? 338 GLN B CD  1 
ATOM   6079 O  OE1 . GLN B 1 338 ? 93.963  103.893 146.601 1.00 44.15  ? 338 GLN B OE1 1 
ATOM   6080 N  NE2 . GLN B 1 338 ? 95.598  102.991 147.849 1.00 44.15  ? 338 GLN B NE2 1 
ATOM   6081 N  N   . LYS B 1 339 ? 96.057  105.526 141.722 1.00 43.64  ? 339 LYS B N   1 
ATOM   6082 C  CA  . LYS B 1 339 ? 95.766  105.977 140.365 1.00 43.64  ? 339 LYS B CA  1 
ATOM   6083 C  C   . LYS B 1 339 ? 96.961  105.788 139.442 1.00 43.64  ? 339 LYS B C   1 
ATOM   6084 O  O   . LYS B 1 339 ? 96.785  105.594 138.234 1.00 43.64  ? 339 LYS B O   1 
ATOM   6085 C  CB  . LYS B 1 339 ? 95.340  107.444 140.376 1.00 43.64  ? 339 LYS B CB  1 
ATOM   6086 C  CG  . LYS B 1 339 ? 93.927  107.687 140.872 1.00 43.64  ? 339 LYS B CG  1 
ATOM   6087 C  CD  . LYS B 1 339 ? 93.311  108.892 140.182 1.00 43.64  ? 339 LYS B CD  1 
ATOM   6088 C  CE  . LYS B 1 339 ? 92.618  109.806 141.177 1.00 43.64  ? 339 LYS B CE  1 
ATOM   6089 N  NZ  . LYS B 1 339 ? 92.615  111.221 140.714 1.00 43.64  ? 339 LYS B NZ  1 
ATOM   6090 N  N   . LEU B 1 340 ? 98.180  105.857 139.984 1.00 37.49  ? 340 LEU B N   1 
ATOM   6091 C  CA  . LEU B 1 340 ? 99.361  105.629 139.155 1.00 37.49  ? 340 LEU B CA  1 
ATOM   6092 C  C   . LEU B 1 340 ? 99.362  104.224 138.563 1.00 37.49  ? 340 LEU B C   1 
ATOM   6093 O  O   . LEU B 1 340 ? 99.711  104.036 137.391 1.00 37.49  ? 340 LEU B O   1 
ATOM   6094 C  CB  . LEU B 1 340 ? 100.633 105.866 139.968 1.00 37.49  ? 340 LEU B CB  1 
ATOM   6095 C  CG  . LEU B 1 340 ? 101.002 107.323 140.238 1.00 37.49  ? 340 LEU B CG  1 
ATOM   6096 C  CD1 . LEU B 1 340 ? 102.216 107.395 141.137 1.00 37.49  ? 340 LEU B CD1 1 
ATOM   6097 C  CD2 . LEU B 1 340 ? 101.257 108.059 138.935 1.00 37.49  ? 340 LEU B CD2 1 
ATOM   6098 N  N   . GLY B 1 341 ? 98.977  103.226 139.353 1.00 35.96  ? 341 GLY B N   1 
ATOM   6099 C  CA  . GLY B 1 341 ? 98.892  101.866 138.879 1.00 35.96  ? 341 GLY B CA  1 
ATOM   6100 C  C   . GLY B 1 341 ? 100.232 101.160 138.837 1.00 35.96  ? 341 GLY B C   1 
ATOM   6101 O  O   . GLY B 1 341 ? 101.210 101.593 139.453 1.00 35.96  ? 341 GLY B O   1 
ATOM   6102 N  N   . PRO B 1 342 ? 100.294 100.045 138.111 1.00 31.01  ? 342 PRO B N   1 
ATOM   6103 C  CA  . PRO B 1 342 ? 101.543 99.280  138.037 1.00 31.01  ? 342 PRO B CA  1 
ATOM   6104 C  C   . PRO B 1 342 ? 102.635 100.046 137.309 1.00 31.01  ? 342 PRO B C   1 
ATOM   6105 O  O   . PRO B 1 342 ? 102.371 100.901 136.460 1.00 31.01  ? 342 PRO B O   1 
ATOM   6106 C  CB  . PRO B 1 342 ? 101.145 98.018  137.262 1.00 31.01  ? 342 PRO B CB  1 
ATOM   6107 C  CG  . PRO B 1 342 ? 99.652  97.963  137.338 1.00 31.01  ? 342 PRO B CG  1 
ATOM   6108 C  CD  . PRO B 1 342 ? 99.201  99.385  137.383 1.00 31.01  ? 342 PRO B CD  1 
ATOM   6109 N  N   . ILE B 1 343 ? 103.883 99.722  137.658 1.00 22.35  ? 343 ILE B N   1 
ATOM   6110 C  CA  . ILE B 1 343 ? 105.024 100.380 137.039 1.00 22.35  ? 343 ILE B CA  1 
ATOM   6111 C  C   . ILE B 1 343 ? 105.076 100.042 135.550 1.00 22.35  ? 343 ILE B C   1 
ATOM   6112 O  O   . ILE B 1 343 ? 104.646 98.966  135.115 1.00 22.35  ? 343 ILE B O   1 
ATOM   6113 C  CB  . ILE B 1 343 ? 106.326 99.978  137.754 1.00 22.35  ? 343 ILE B CB  1 
ATOM   6114 C  CG1 . ILE B 1 343 ? 107.477 100.902 137.353 1.00 22.35  ? 343 ILE B CG1 1 
ATOM   6115 C  CG2 . ILE B 1 343 ? 106.674 98.527  137.470 1.00 22.35  ? 343 ILE B CG2 1 
ATOM   6116 C  CD1 . ILE B 1 343 ? 108.696 100.773 138.237 1.00 22.35  ? 343 ILE B CD1 1 
ATOM   6117 N  N   . ARG B 1 344 ? 105.587 100.979 134.760 1.00 18.95  ? 344 ARG B N   1 
ATOM   6118 C  CA  . ARG B 1 344 ? 105.679 100.828 133.317 1.00 18.95  ? 344 ARG B CA  1 
ATOM   6119 C  C   . ARG B 1 344 ? 107.095 100.448 132.901 1.00 18.95  ? 344 ARG B C   1 
ATOM   6120 O  O   . ARG B 1 344 ? 108.054 100.593 133.662 1.00 18.95  ? 344 ARG B O   1 
ATOM   6121 C  CB  . ARG B 1 344 ? 105.252 102.115 132.608 1.00 18.95  ? 344 ARG B CB  1 
ATOM   6122 C  CG  . ARG B 1 344 ? 103.760 102.207 132.343 1.00 18.95  ? 344 ARG B CG  1 
ATOM   6123 C  CD  . ARG B 1 344 ? 103.403 103.487 131.607 1.00 18.95  ? 344 ARG B CD  1 
ATOM   6124 N  NE  . ARG B 1 344 ? 103.964 104.667 132.255 1.00 18.95  ? 344 ARG B NE  1 
ATOM   6125 C  CZ  . ARG B 1 344 ? 104.250 105.800 131.629 1.00 18.95  ? 344 ARG B CZ  1 
ATOM   6126 N  NH1 . ARG B 1 344 ? 104.041 105.945 130.331 1.00 18.95  ? 344 ARG B NH1 1 
ATOM   6127 N  NH2 . ARG B 1 344 ? 104.756 106.815 132.323 1.00 18.95  ? 344 ARG B NH2 1 
ATOM   6128 N  N   . TYR B 1 345 ? 107.210 99.953  131.667 1.00 16.54  ? 345 TYR B N   1 
ATOM   6129 C  CA  . TYR B 1 345 ? 108.504 99.521  131.148 1.00 16.54  ? 345 TYR B CA  1 
ATOM   6130 C  C   . TYR B 1 345 ? 109.482 100.685 131.047 1.00 16.54  ? 345 TYR B C   1 
ATOM   6131 O  O   . TYR B 1 345 ? 110.669 100.541 131.371 1.00 16.54  ? 345 TYR B O   1 
ATOM   6132 C  CB  . TYR B 1 345 ? 108.311 98.851  129.788 1.00 16.54  ? 345 TYR B CB  1 
ATOM   6133 C  CG  . TYR B 1 345 ? 109.514 98.908  128.877 1.00 16.54  ? 345 TYR B CG  1 
ATOM   6134 C  CD1 . TYR B 1 345 ? 110.595 98.062  129.068 1.00 16.54  ? 345 TYR B CD1 1 
ATOM   6135 C  CD2 . TYR B 1 345 ? 109.561 99.800  127.816 1.00 16.54  ? 345 TYR B CD2 1 
ATOM   6136 C  CE1 . TYR B 1 345 ? 111.690 98.109  128.232 1.00 16.54  ? 345 TYR B CE1 1 
ATOM   6137 C  CE2 . TYR B 1 345 ? 110.653 99.855  126.978 1.00 16.54  ? 345 TYR B CE2 1 
ATOM   6138 C  CZ  . TYR B 1 345 ? 111.714 99.009  127.191 1.00 16.54  ? 345 TYR B CZ  1 
ATOM   6139 O  OH  . TYR B 1 345 ? 112.804 99.061  126.355 1.00 16.54  ? 345 TYR B OH  1 
ATOM   6140 N  N   . GLN B 1 346 ? 109.004 101.847 130.596 1.00 15.51  ? 346 GLN B N   1 
ATOM   6141 C  CA  . GLN B 1 346 ? 109.875 103.011 130.475 1.00 15.51  ? 346 GLN B CA  1 
ATOM   6142 C  C   . GLN B 1 346 ? 110.415 103.440 131.833 1.00 15.51  ? 346 GLN B C   1 
ATOM   6143 O  O   . GLN B 1 346 ? 111.593 103.791 131.960 1.00 15.51  ? 346 GLN B O   1 
ATOM   6144 C  CB  . GLN B 1 346 ? 109.123 104.163 129.811 1.00 15.51  ? 346 GLN B CB  1 
ATOM   6145 C  CG  . GLN B 1 346 ? 108.743 103.914 128.362 1.00 15.51  ? 346 GLN B CG  1 
ATOM   6146 C  CD  . GLN B 1 346 ? 107.422 103.190 128.220 1.00 15.51  ? 346 GLN B CD  1 
ATOM   6147 O  OE1 . GLN B 1 346 ? 107.346 102.125 127.612 1.00 15.51  ? 346 GLN B OE1 1 
ATOM   6148 N  NE2 . GLN B 1 346 ? 106.370 103.767 128.785 1.00 15.51  ? 346 GLN B NE2 1 
ATOM   6149 N  N   . GLU B 1 347 ? 109.565 103.415 132.862 1.00 17.26  ? 347 GLU B N   1 
ATOM   6150 C  CA  . GLU B 1 347 ? 110.018 103.761 134.204 1.00 17.26  ? 347 GLU B CA  1 
ATOM   6151 C  C   . GLU B 1 347 ? 111.046 102.761 134.716 1.00 17.26  ? 347 GLU B C   1 
ATOM   6152 O  O   . GLU B 1 347 ? 112.012 103.144 135.384 1.00 17.26  ? 347 GLU B O   1 
ATOM   6153 C  CB  . GLU B 1 347 ? 108.825 103.843 135.153 1.00 17.26  ? 347 GLU B CB  1 
ATOM   6154 C  CG  . GLU B 1 347 ? 107.642 104.603 134.584 1.00 17.26  ? 347 GLU B CG  1 
ATOM   6155 C  CD  . GLU B 1 347 ? 106.481 104.682 135.551 1.00 17.26  ? 347 GLU B CD  1 
ATOM   6156 O  OE1 . GLU B 1 347 ? 106.662 104.314 136.729 1.00 17.26  ? 347 GLU B OE1 1 
ATOM   6157 O  OE2 . GLU B 1 347 ? 105.387 105.113 135.134 1.00 17.26  ? 347 GLU B OE2 1 
ATOM   6158 N  N   . ILE B 1 348 ? 110.856 101.473 134.417 1.00 14.41  ? 348 ILE B N   1 
ATOM   6159 C  CA  . ILE B 1 348 ? 111.825 100.463 134.836 1.00 14.41  ? 348 ILE B CA  1 
ATOM   6160 C  C   . ILE B 1 348 ? 113.172 100.705 134.169 1.00 14.41  ? 348 ILE B C   1 
ATOM   6161 O  O   . ILE B 1 348 ? 114.225 100.635 134.818 1.00 14.41  ? 348 ILE B O   1 
ATOM   6162 C  CB  . ILE B 1 348 ? 111.295 99.050  134.533 1.00 14.41  ? 348 ILE B CB  1 
ATOM   6163 C  CG1 . ILE B 1 348 ? 110.056 98.750  135.373 1.00 14.41  ? 348 ILE B CG1 1 
ATOM   6164 C  CG2 . ILE B 1 348 ? 112.368 98.016  134.803 1.00 14.41  ? 348 ILE B CG2 1 
ATOM   6165 C  CD1 . ILE B 1 348 ? 109.347 97.478  134.971 1.00 14.41  ? 348 ILE B CD1 1 
ATOM   6166 N  N   . VAL B 1 349 ? 113.164 100.990 132.865 1.00 12.65  ? 349 VAL B N   1 
ATOM   6167 C  CA  . VAL B 1 349 ? 114.416 101.252 132.159 1.00 12.65  ? 349 VAL B CA  1 
ATOM   6168 C  C   . VAL B 1 349 ? 115.093 102.499 132.714 1.00 12.65  ? 349 VAL B C   1 
ATOM   6169 O  O   . VAL B 1 349 ? 116.316 102.528 132.901 1.00 12.65  ? 349 VAL B O   1 
ATOM   6170 C  CB  . VAL B 1 349 ? 114.163 101.368 130.645 1.00 12.65  ? 349 VAL B CB  1 
ATOM   6171 C  CG1 . VAL B 1 349 ? 115.334 102.044 129.961 1.00 12.65  ? 349 VAL B CG1 1 
ATOM   6172 C  CG2 . VAL B 1 349 ? 113.933 99.998  130.049 1.00 12.65  ? 349 VAL B CG2 1 
ATOM   6173 N  N   . THR B 1 350 ? 114.312 103.549 132.981 1.00 12.20  ? 350 THR B N   1 
ATOM   6174 C  CA  . THR B 1 350 ? 114.883 104.772 133.535 1.00 12.20  ? 350 THR B CA  1 
ATOM   6175 C  C   . THR B 1 350 ? 115.488 104.529 134.911 1.00 12.20  ? 350 THR B C   1 
ATOM   6176 O  O   . THR B 1 350 ? 116.566 105.047 135.222 1.00 12.20  ? 350 THR B O   1 
ATOM   6177 C  CB  . THR B 1 350 ? 113.819 105.862 133.610 1.00 12.20  ? 350 THR B CB  1 
ATOM   6178 O  OG1 . THR B 1 350 ? 113.142 105.956 132.352 1.00 12.20  ? 350 THR B OG1 1 
ATOM   6179 C  CG2 . THR B 1 350 ? 114.459 107.195 133.930 1.00 12.20  ? 350 THR B CG2 1 
ATOM   6180 N  N   . LEU B 1 351 ? 114.809 103.745 135.751 1.00 12.65  ? 351 LEU B N   1 
ATOM   6181 C  CA  . LEU B 1 351 ? 115.349 103.419 137.066 1.00 12.65  ? 351 LEU B CA  1 
ATOM   6182 C  C   . LEU B 1 351 ? 116.643 102.625 136.952 1.00 12.65  ? 351 LEU B C   1 
ATOM   6183 O  O   . LEU B 1 351 ? 117.607 102.881 137.685 1.00 12.65  ? 351 LEU B O   1 
ATOM   6184 C  CB  . LEU B 1 351 ? 114.313 102.636 137.872 1.00 12.65  ? 351 LEU B CB  1 
ATOM   6185 C  CG  . LEU B 1 351 ? 114.387 102.730 139.394 1.00 12.65  ? 351 LEU B CG  1 
ATOM   6186 C  CD1 . LEU B 1 351 ? 114.402 104.180 139.845 1.00 12.65  ? 351 LEU B CD1 1 
ATOM   6187 C  CD2 . LEU B 1 351 ? 113.226 101.979 140.023 1.00 12.65  ? 351 LEU B CD2 1 
ATOM   6188 N  N   . VAL B 1 352 ? 116.683 101.653 136.038 1.00 11.75  ? 352 VAL B N   1 
ATOM   6189 C  CA  . VAL B 1 352 ? 117.889 100.850 135.862 1.00 11.75  ? 352 VAL B CA  1 
ATOM   6190 C  C   . VAL B 1 352 ? 119.046 101.721 135.392 1.00 11.75  ? 352 VAL B C   1 
ATOM   6191 O  O   . VAL B 1 352 ? 120.180 101.581 135.867 1.00 11.75  ? 352 VAL B O   1 
ATOM   6192 C  CB  . VAL B 1 352 ? 117.620 99.687  134.892 1.00 11.75  ? 352 VAL B CB  1 
ATOM   6193 C  CG1 . VAL B 1 352 ? 118.926 99.100  134.390 1.00 11.75  ? 352 VAL B CG1 1 
ATOM   6194 C  CG2 . VAL B 1 352 ? 116.785 98.620  135.574 1.00 11.75  ? 352 VAL B CG2 1 
ATOM   6195 N  N   . LEU B 1 353 ? 118.784 102.633 134.455 1.00 11.23  ? 353 LEU B N   1 
ATOM   6196 C  CA  . LEU B 1 353 ? 119.847 103.511 133.977 1.00 11.23  ? 353 LEU B CA  1 
ATOM   6197 C  C   . LEU B 1 353 ? 120.295 104.492 135.054 1.00 11.23  ? 353 LEU B C   1 
ATOM   6198 O  O   . LEU B 1 353 ? 121.483 104.818 135.133 1.00 11.23  ? 353 LEU B O   1 
ATOM   6199 C  CB  . LEU B 1 353 ? 119.392 104.249 132.721 1.00 11.23  ? 353 LEU B CB  1 
ATOM   6200 C  CG  . LEU B 1 353 ? 119.376 103.369 131.469 1.00 11.23  ? 353 LEU B CG  1 
ATOM   6201 C  CD1 . LEU B 1 353 ? 118.828 104.116 130.271 1.00 11.23  ? 353 LEU B CD1 1 
ATOM   6202 C  CD2 . LEU B 1 353 ? 120.769 102.843 131.176 1.00 11.23  ? 353 LEU B CD2 1 
ATOM   6203 N  N   . PHE B 1 354 ? 119.370 104.960 135.894 1.00 14.26  ? 354 PHE B N   1 
ATOM   6204 C  CA  . PHE B 1 354 ? 119.740 105.780 137.044 1.00 14.26  ? 354 PHE B CA  1 
ATOM   6205 C  C   . PHE B 1 354 ? 120.680 105.025 137.976 1.00 14.26  ? 354 PHE B C   1 
ATOM   6206 O  O   . PHE B 1 354 ? 121.713 105.555 138.409 1.00 14.26  ? 354 PHE B O   1 
ATOM   6207 C  CB  . PHE B 1 354 ? 118.474 106.208 137.788 1.00 14.26  ? 354 PHE B CB  1 
ATOM   6208 C  CG  . PHE B 1 354 ? 118.726 107.087 138.975 1.00 14.26  ? 354 PHE B CG  1 
ATOM   6209 C  CD1 . PHE B 1 354 ? 119.048 108.419 138.815 1.00 14.26  ? 354 PHE B CD1 1 
ATOM   6210 C  CD2 . PHE B 1 354 ? 118.633 106.577 140.257 1.00 14.26  ? 354 PHE B CD2 1 
ATOM   6211 C  CE1 . PHE B 1 354 ? 119.275 109.227 139.910 1.00 14.26  ? 354 PHE B CE1 1 
ATOM   6212 C  CE2 . PHE B 1 354 ? 118.861 107.378 141.356 1.00 14.26  ? 354 PHE B CE2 1 
ATOM   6213 C  CZ  . PHE B 1 354 ? 119.182 108.705 141.182 1.00 14.26  ? 354 PHE B CZ  1 
ATOM   6214 N  N   . ILE B 1 355 ? 120.335 103.774 138.288 1.00 13.05  ? 355 ILE B N   1 
ATOM   6215 C  CA  . ILE B 1 355 ? 121.169 102.966 139.173 1.00 13.05  ? 355 ILE B CA  1 
ATOM   6216 C  C   . ILE B 1 355 ? 122.537 102.730 138.548 1.00 13.05  ? 355 ILE B C   1 
ATOM   6217 O  O   . ILE B 1 355 ? 123.566 102.789 139.231 1.00 13.05  ? 355 ILE B O   1 
ATOM   6218 C  CB  . ILE B 1 355 ? 120.461 101.640 139.510 1.00 13.05  ? 355 ILE B CB  1 
ATOM   6219 C  CG1 . ILE B 1 355 ? 119.174 101.907 140.290 1.00 13.05  ? 355 ILE B CG1 1 
ATOM   6220 C  CG2 . ILE B 1 355 ? 121.380 100.729 140.301 1.00 13.05  ? 355 ILE B CG2 1 
ATOM   6221 C  CD1 . ILE B 1 355 ? 119.357 102.825 141.472 1.00 13.05  ? 355 ILE B CD1 1 
ATOM   6222 N  N   . ILE B 1 356 ? 122.571 102.457 137.243 1.00 12.48  ? 356 ILE B N   1 
ATOM   6223 C  CA  . ILE B 1 356 ? 123.841 102.211 136.565 1.00 12.48  ? 356 ILE B CA  1 
ATOM   6224 C  C   . ILE B 1 356 ? 124.710 103.463 136.579 1.00 12.48  ? 356 ILE B C   1 
ATOM   6225 O  O   . ILE B 1 356 ? 125.920 103.389 136.822 1.00 12.48  ? 356 ILE B O   1 
ATOM   6226 C  CB  . ILE B 1 356 ? 123.594 101.700 135.135 1.00 12.48  ? 356 ILE B CB  1 
ATOM   6227 C  CG1 . ILE B 1 356 ? 123.153 100.238 135.166 1.00 12.48  ? 356 ILE B CG1 1 
ATOM   6228 C  CG2 . ILE B 1 356 ? 124.841 101.847 134.288 1.00 12.48  ? 356 ILE B CG2 1 
ATOM   6229 C  CD1 . ILE B 1 356 ? 122.643 99.729  133.841 1.00 12.48  ? 356 ILE B CD1 1 
ATOM   6230 N  N   . MET B 1 357 ? 124.113 104.630 136.322 1.00 13.89  ? 357 MET B N   1 
ATOM   6231 C  CA  . MET B 1 357 ? 124.872 105.877 136.375 1.00 13.89  ? 357 MET B CA  1 
ATOM   6232 C  C   . MET B 1 357 ? 125.449 106.108 137.765 1.00 13.89  ? 357 MET B C   1 
ATOM   6233 O  O   . MET B 1 357 ? 126.626 106.461 137.911 1.00 13.89  ? 357 MET B O   1 
ATOM   6234 C  CB  . MET B 1 357 ? 123.988 107.058 135.976 1.00 13.89  ? 357 MET B CB  1 
ATOM   6235 C  CG  . MET B 1 357 ? 124.771 108.296 135.567 1.00 13.89  ? 357 MET B CG  1 
ATOM   6236 S  SD  . MET B 1 357 ? 123.738 109.671 135.023 1.00 13.89  ? 357 MET B SD  1 
ATOM   6237 C  CE  . MET B 1 357 ? 122.895 108.956 133.620 1.00 13.89  ? 357 MET B CE  1 
ATOM   6238 N  N   . ALA B 1 358 ? 124.629 105.916 138.802 1.00 14.56  ? 358 ALA B N   1 
ATOM   6239 C  CA  . ALA B 1 358 ? 125.107 106.137 140.163 1.00 14.56  ? 358 ALA B CA  1 
ATOM   6240 C  C   . ALA B 1 358 ? 126.229 105.170 140.522 1.00 14.56  ? 358 ALA B C   1 
ATOM   6241 O  O   . ALA B 1 358 ? 127.237 105.570 141.118 1.00 14.56  ? 358 ALA B O   1 
ATOM   6242 C  CB  . ALA B 1 358 ? 123.950 106.011 141.153 1.00 14.56  ? 358 ALA B CB  1 
ATOM   6243 N  N   . LEU B 1 359 ? 126.076 103.894 140.162 1.00 15.24  ? 359 LEU B N   1 
ATOM   6244 C  CA  . LEU B 1 359 ? 127.107 102.908 140.469 1.00 15.24  ? 359 LEU B CA  1 
ATOM   6245 C  C   . LEU B 1 359 ? 128.399 103.205 139.721 1.00 15.24  ? 359 LEU B C   1 
ATOM   6246 O  O   . LEU B 1 359 ? 129.492 103.050 140.278 1.00 15.24  ? 359 LEU B O   1 
ATOM   6247 C  CB  . LEU B 1 359 ? 126.608 101.503 140.139 1.00 15.24  ? 359 LEU B CB  1 
ATOM   6248 C  CG  . LEU B 1 359 ? 125.517 100.930 141.046 1.00 15.24  ? 359 LEU B CG  1 
ATOM   6249 C  CD1 . LEU B 1 359 ? 125.379 99.432  140.831 1.00 15.24  ? 359 LEU B CD1 1 
ATOM   6250 C  CD2 . LEU B 1 359 ? 125.804 101.243 142.504 1.00 15.24  ? 359 LEU B CD2 1 
ATOM   6251 N  N   . LEU B 1 360 ? 128.298 103.622 138.458 1.00 15.13  ? 360 LEU B N   1 
ATOM   6252 C  CA  . LEU B 1 360 ? 129.495 103.948 137.692 1.00 15.13  ? 360 LEU B CA  1 
ATOM   6253 C  C   . LEU B 1 360 ? 130.191 105.180 138.255 1.00 15.13  ? 360 LEU B C   1 
ATOM   6254 O  O   . LEU B 1 360 ? 131.424 105.261 138.241 1.00 15.13  ? 360 LEU B O   1 
ATOM   6255 C  CB  . LEU B 1 360 ? 129.134 104.154 136.223 1.00 15.13  ? 360 LEU B CB  1 
ATOM   6256 C  CG  . LEU B 1 360 ? 128.999 102.898 135.363 1.00 15.13  ? 360 LEU B CG  1 
ATOM   6257 C  CD1 . LEU B 1 360 ? 128.960 103.265 133.893 1.00 15.13  ? 360 LEU B CD1 1 
ATOM   6258 C  CD2 . LEU B 1 360 ? 130.135 101.936 135.643 1.00 15.13  ? 360 LEU B CD2 1 
ATOM   6259 N  N   . TRP B 1 361 ? 129.420 106.156 138.740 1.00 15.70  ? 361 TRP B N   1 
ATOM   6260 C  CA  . TRP B 1 361 ? 130.027 107.303 139.409 1.00 15.70  ? 361 TRP B CA  1 
ATOM   6261 C  C   . TRP B 1 361 ? 130.736 106.881 140.688 1.00 15.70  ? 361 TRP B C   1 
ATOM   6262 O  O   . TRP B 1 361 ? 131.843 107.350 140.977 1.00 15.70  ? 361 TRP B O   1 
ATOM   6263 C  CB  . TRP B 1 361 ? 128.968 108.356 139.723 1.00 15.70  ? 361 TRP B CB  1 
ATOM   6264 C  CG  . TRP B 1 361 ? 128.729 109.317 138.618 1.00 15.70  ? 361 TRP B CG  1 
ATOM   6265 C  CD1 . TRP B 1 361 ? 129.594 109.651 137.622 1.00 15.70  ? 361 TRP B CD1 1 
ATOM   6266 C  CD2 . TRP B 1 361 ? 127.543 110.081 138.394 1.00 15.70  ? 361 TRP B CD2 1 
ATOM   6267 N  NE1 . TRP B 1 361 ? 129.017 110.574 136.787 1.00 15.70  ? 361 TRP B NE1 1 
ATOM   6268 C  CE2 . TRP B 1 361 ? 127.757 110.855 137.241 1.00 15.70  ? 361 TRP B CE2 1 
ATOM   6269 C  CE3 . TRP B 1 361 ? 126.319 110.184 139.059 1.00 15.70  ? 361 TRP B CE3 1 
ATOM   6270 C  CZ2 . TRP B 1 361 ? 126.793 111.719 136.737 1.00 15.70  ? 361 TRP B CZ2 1 
ATOM   6271 C  CZ3 . TRP B 1 361 ? 125.366 111.042 138.557 1.00 15.70  ? 361 TRP B CZ3 1 
ATOM   6272 C  CH2 . TRP B 1 361 ? 125.607 111.798 137.408 1.00 15.70  ? 361 TRP B CH2 1 
ATOM   6273 N  N   . PHE B 1 362 ? 130.111 105.998 141.468 1.00 23.62  ? 362 PHE B N   1 
ATOM   6274 C  CA  . PHE B 1 362 ? 130.718 105.550 142.715 1.00 23.62  ? 362 PHE B CA  1 
ATOM   6275 C  C   . PHE B 1 362 ? 131.955 104.694 142.470 1.00 23.62  ? 362 PHE B C   1 
ATOM   6276 O  O   . PHE B 1 362 ? 132.866 104.675 143.304 1.00 23.62  ? 362 PHE B O   1 
ATOM   6277 C  CB  . PHE B 1 362 ? 129.688 104.779 143.542 1.00 23.62  ? 362 PHE B CB  1 
ATOM   6278 C  CG  . PHE B 1 362 ? 130.232 104.217 144.822 1.00 23.62  ? 362 PHE B CG  1 
ATOM   6279 C  CD1 . PHE B 1 362 ? 130.943 105.015 145.700 1.00 23.62  ? 362 PHE B CD1 1 
ATOM   6280 C  CD2 . PHE B 1 362 ? 130.029 102.889 145.148 1.00 23.62  ? 362 PHE B CD2 1 
ATOM   6281 C  CE1 . PHE B 1 362 ? 131.444 104.497 146.876 1.00 23.62  ? 362 PHE B CE1 1 
ATOM   6282 C  CE2 . PHE B 1 362 ? 130.527 102.366 146.324 1.00 23.62  ? 362 PHE B CE2 1 
ATOM   6283 C  CZ  . PHE B 1 362 ? 131.235 103.171 147.188 1.00 23.62  ? 362 PHE B CZ  1 
ATOM   6284 N  N   . SER B 1 363 ? 132.014 103.993 141.341 1.00 24.00  ? 363 SER B N   1 
ATOM   6285 C  CA  . SER B 1 363 ? 133.070 103.026 141.075 1.00 24.00  ? 363 SER B CA  1 
ATOM   6286 C  C   . SER B 1 363 ? 134.231 103.599 140.271 1.00 24.00  ? 363 SER B C   1 
ATOM   6287 O  O   . SER B 1 363 ? 135.126 102.842 139.887 1.00 24.00  ? 363 SER B O   1 
ATOM   6288 C  CB  . SER B 1 363 ? 132.495 101.812 140.348 1.00 24.00  ? 363 SER B CB  1 
ATOM   6289 O  OG  . SER B 1 363 ? 131.522 101.161 141.145 1.00 24.00  ? 363 SER B OG  1 
ATOM   6290 N  N   . ARG B 1 364 ? 134.233 104.903 139.988 1.00 29.55  ? 364 ARG B N   1 
ATOM   6291 C  CA  . ARG B 1 364 ? 135.357 105.496 139.269 1.00 29.55  ? 364 ARG B CA  1 
ATOM   6292 C  C   . ARG B 1 364 ? 136.636 105.428 140.093 1.00 29.55  ? 364 ARG B C   1 
ATOM   6293 O  O   . ARG B 1 364 ? 137.673 104.952 139.617 1.00 29.55  ? 364 ARG B O   1 
ATOM   6294 C  CB  . ARG B 1 364 ? 135.041 106.943 138.898 1.00 29.55  ? 364 ARG B CB  1 
ATOM   6295 C  CG  . ARG B 1 364 ? 135.645 107.387 137.580 1.00 29.55  ? 364 ARG B CG  1 
ATOM   6296 C  CD  . ARG B 1 364 ? 135.526 108.885 137.400 1.00 29.55  ? 364 ARG B CD  1 
ATOM   6297 N  NE  . ARG B 1 364 ? 135.793 109.592 138.645 1.00 29.55  ? 364 ARG B NE  1 
ATOM   6298 C  CZ  . ARG B 1 364 ? 136.989 110.018 139.025 1.00 29.55  ? 364 ARG B CZ  1 
ATOM   6299 N  NH1 . ARG B 1 364 ? 138.058 109.840 138.268 1.00 29.55  ? 364 ARG B NH1 1 
ATOM   6300 N  NH2 . ARG B 1 364 ? 137.116 110.636 140.196 1.00 29.55  ? 364 ARG B NH2 1 
ATOM   6301 N  N   . ASP B 1 365 ? 136.579 105.900 141.332 1.00 43.28  ? 365 ASP B N   1 
ATOM   6302 C  CA  . ASP B 1 365 ? 137.736 105.919 142.217 1.00 43.28  ? 365 ASP B CA  1 
ATOM   6303 C  C   . ASP B 1 365 ? 137.267 106.074 143.657 1.00 43.28  ? 365 ASP B C   1 
ATOM   6304 O  O   . ASP B 1 365 ? 137.303 107.183 144.204 1.00 43.28  ? 365 ASP B O   1 
ATOM   6305 C  CB  . ASP B 1 365 ? 138.690 107.052 141.838 1.00 43.28  ? 365 ASP B CB  1 
ATOM   6306 C  CG  . ASP B 1 365 ? 140.013 106.968 142.569 1.00 43.28  ? 365 ASP B CG  1 
ATOM   6307 O  OD1 . ASP B 1 365 ? 140.856 106.132 142.181 1.00 43.28  ? 365 ASP B OD1 1 
ATOM   6308 O  OD2 . ASP B 1 365 ? 140.211 107.737 143.532 1.00 43.28  ? 365 ASP B OD2 1 
ATOM   6309 N  N   . PRO B 1 366 ? 136.808 104.995 144.296 1.00 47.47  ? 366 PRO B N   1 
ATOM   6310 C  CA  . PRO B 1 366 ? 136.313 105.120 145.676 1.00 47.47  ? 366 PRO B CA  1 
ATOM   6311 C  C   . PRO B 1 366 ? 137.361 105.618 146.655 1.00 47.47  ? 366 PRO B C   1 
ATOM   6312 O  O   . PRO B 1 366 ? 137.008 106.258 147.654 1.00 47.47  ? 366 PRO B O   1 
ATOM   6313 C  CB  . PRO B 1 366 ? 135.854 103.694 146.013 1.00 47.47  ? 366 PRO B CB  1 
ATOM   6314 C  CG  . PRO B 1 366 ? 135.653 103.029 144.692 1.00 47.47  ? 366 PRO B CG  1 
ATOM   6315 C  CD  . PRO B 1 366 ? 136.675 103.624 143.782 1.00 47.47  ? 366 PRO B CD  1 
ATOM   6316 N  N   . GLY B 1 367 ? 138.638 105.343 146.405 1.00 56.33  ? 367 GLY B N   1 
ATOM   6317 C  CA  . GLY B 1 367 ? 139.714 105.778 147.263 1.00 56.33  ? 367 GLY B CA  1 
ATOM   6318 C  C   . GLY B 1 367 ? 140.174 104.744 148.268 1.00 56.33  ? 367 GLY B C   1 
ATOM   6319 O  O   . GLY B 1 367 ? 141.285 104.866 148.797 1.00 56.33  ? 367 GLY B O   1 
ATOM   6320 N  N   . PHE B 1 368 ? 139.351 103.732 148.545 1.00 55.52  ? 368 PHE B N   1 
ATOM   6321 C  CA  . PHE B 1 368 ? 139.736 102.634 149.417 1.00 55.52  ? 368 PHE B CA  1 
ATOM   6322 C  C   . PHE B 1 368 ? 139.871 101.308 148.687 1.00 55.52  ? 368 PHE B C   1 
ATOM   6323 O  O   . PHE B 1 368 ? 140.604 100.434 149.159 1.00 55.52  ? 368 PHE B O   1 
ATOM   6324 C  CB  . PHE B 1 368 ? 138.723 102.475 150.561 1.00 55.52  ? 368 PHE B CB  1 
ATOM   6325 C  CG  . PHE B 1 368 ? 137.289 102.559 150.121 1.00 55.52  ? 368 PHE B CG  1 
ATOM   6326 C  CD1 . PHE B 1 368 ? 136.617 101.431 149.686 1.00 55.52  ? 368 PHE B CD1 1 
ATOM   6327 C  CD2 . PHE B 1 368 ? 136.612 103.766 150.150 1.00 55.52  ? 368 PHE B CD2 1 
ATOM   6328 C  CE1 . PHE B 1 368 ? 135.297 101.505 149.283 1.00 55.52  ? 368 PHE B CE1 1 
ATOM   6329 C  CE2 . PHE B 1 368 ? 135.294 103.845 149.748 1.00 55.52  ? 368 PHE B CE2 1 
ATOM   6330 C  CZ  . PHE B 1 368 ? 134.636 102.714 149.314 1.00 55.52  ? 368 PHE B CZ  1 
ATOM   6331 N  N   . VAL B 1 369 ? 139.186 101.138 147.561 1.00 58.67  ? 369 VAL B N   1 
ATOM   6332 C  CA  . VAL B 1 369 ? 139.345 99.961  146.711 1.00 58.67  ? 369 VAL B CA  1 
ATOM   6333 C  C   . VAL B 1 369 ? 139.537 100.449 145.280 1.00 58.67  ? 369 VAL B C   1 
ATOM   6334 O  O   . VAL B 1 369 ? 139.024 101.519 144.922 1.00 58.67  ? 369 VAL B O   1 
ATOM   6335 C  CB  . VAL B 1 369 ? 138.141 99.014  146.828 1.00 58.67  ? 369 VAL B CB  1 
ATOM   6336 C  CG1 . VAL B 1 369 ? 138.087 98.392  148.214 1.00 58.67  ? 369 VAL B CG1 1 
ATOM   6337 C  CG2 . VAL B 1 369 ? 136.850 99.753  146.522 1.00 58.67  ? 369 VAL B CG2 1 
ATOM   6338 N  N   . PRO B 1 370 ? 140.275 99.725  144.441 1.00 56.56  ? 370 PRO B N   1 
ATOM   6339 C  CA  . PRO B 1 370 ? 140.452 100.168 143.053 1.00 56.56  ? 370 PRO B CA  1 
ATOM   6340 C  C   . PRO B 1 370 ? 139.123 100.231 142.315 1.00 56.56  ? 370 PRO B C   1 
ATOM   6341 O  O   . PRO B 1 370 ? 138.237 99.399  142.520 1.00 56.56  ? 370 PRO B O   1 
ATOM   6342 C  CB  . PRO B 1 370 ? 141.378 99.103  142.455 1.00 56.56  ? 370 PRO B CB  1 
ATOM   6343 C  CG  . PRO B 1 370 ? 142.074 98.499  143.629 1.00 56.56  ? 370 PRO B CG  1 
ATOM   6344 C  CD  . PRO B 1 370 ? 141.073 98.526  144.744 1.00 56.56  ? 370 PRO B CD  1 
ATOM   6345 N  N   . GLY B 1 371 ? 138.990 101.236 141.451 1.00 37.16  ? 371 GLY B N   1 
ATOM   6346 C  CA  . GLY B 1 371 ? 137.814 101.400 140.628 1.00 37.16  ? 371 GLY B CA  1 
ATOM   6347 C  C   . GLY B 1 371 ? 138.030 100.889 139.216 1.00 37.16  ? 371 GLY B C   1 
ATOM   6348 O  O   . GLY B 1 371 ? 138.982 100.165 138.918 1.00 37.16  ? 371 GLY B O   1 
ATOM   6349 N  N   . TRP B 1 372 ? 137.115 101.278 138.328 1.00 28.16  ? 372 TRP B N   1 
ATOM   6350 C  CA  . TRP B 1 372 ? 137.261 100.891 136.932 1.00 28.16  ? 372 TRP B CA  1 
ATOM   6351 C  C   . TRP B 1 372 ? 138.252 101.768 136.186 1.00 28.16  ? 372 TRP B C   1 
ATOM   6352 O  O   . TRP B 1 372 ? 138.634 101.424 135.063 1.00 28.16  ? 372 TRP B O   1 
ATOM   6353 C  CB  . TRP B 1 372 ? 135.897 100.894 136.226 1.00 28.16  ? 372 TRP B CB  1 
ATOM   6354 C  CG  . TRP B 1 372 ? 135.155 102.204 136.183 1.00 28.16  ? 372 TRP B CG  1 
ATOM   6355 C  CD1 . TRP B 1 372 ? 133.996 102.498 136.837 1.00 28.16  ? 372 TRP B CD1 1 
ATOM   6356 C  CD2 . TRP B 1 372 ? 135.456 103.351 135.373 1.00 28.16  ? 372 TRP B CD2 1 
ATOM   6357 N  NE1 . TRP B 1 372 ? 133.587 103.771 136.531 1.00 28.16  ? 372 TRP B NE1 1 
ATOM   6358 C  CE2 . TRP B 1 372 ? 134.463 104.314 135.630 1.00 28.16  ? 372 TRP B CE2 1 
ATOM   6359 C  CE3 . TRP B 1 372 ? 136.479 103.666 134.473 1.00 28.16  ? 372 TRP B CE3 1 
ATOM   6360 C  CZ2 . TRP B 1 372 ? 134.463 105.565 135.021 1.00 28.16  ? 372 TRP B CZ2 1 
ATOM   6361 C  CZ3 . TRP B 1 372 ? 136.479 104.911 133.875 1.00 28.16  ? 372 TRP B CZ3 1 
ATOM   6362 C  CH2 . TRP B 1 372 ? 135.479 105.844 134.151 1.00 28.16  ? 372 TRP B CH2 1 
ATOM   6363 N  N   . SER B 1 373 ? 138.680 102.884 136.780 1.00 29.41  ? 373 SER B N   1 
ATOM   6364 C  CA  . SER B 1 373 ? 139.716 103.705 136.168 1.00 29.41  ? 373 SER B CA  1 
ATOM   6365 C  C   . SER B 1 373 ? 141.046 102.972 136.078 1.00 29.41  ? 373 SER B C   1 
ATOM   6366 O  O   . SER B 1 373 ? 141.893 103.349 135.262 1.00 29.41  ? 373 SER B O   1 
ATOM   6367 C  CB  . SER B 1 373 ? 139.890 105.004 136.952 1.00 29.41  ? 373 SER B CB  1 
ATOM   6368 O  OG  . SER B 1 373 ? 140.626 104.781 138.140 1.00 29.41  ? 373 SER B OG  1 
ATOM   6369 N  N   . ALA B 1 374 ? 141.251 101.940 136.900 1.00 33.01  ? 374 ALA B N   1 
ATOM   6370 C  CA  . ALA B 1 374 ? 142.447 101.116 136.780 1.00 33.01  ? 374 ALA B CA  1 
ATOM   6371 C  C   . ALA B 1 374 ? 142.470 100.326 135.480 1.00 33.01  ? 374 ALA B C   1 
ATOM   6372 O  O   . ALA B 1 374 ? 143.549 99.923  135.034 1.00 33.01  ? 374 ALA B O   1 
ATOM   6373 C  CB  . ALA B 1 374 ? 142.556 100.168 137.973 1.00 33.01  ? 374 ALA B CB  1 
ATOM   6374 N  N   . LEU B 1 375 ? 141.308 100.083 134.869 1.00 31.71  ? 375 LEU B N   1 
ATOM   6375 C  CA  . LEU B 1 375 ? 141.292 99.507  133.529 1.00 31.71  ? 375 LEU B CA  1 
ATOM   6376 C  C   . LEU B 1 375 ? 141.943 100.453 132.530 1.00 31.71  ? 375 LEU B C   1 
ATOM   6377 O  O   . LEU B 1 375 ? 142.583 100.013 131.568 1.00 31.71  ? 375 LEU B O   1 
ATOM   6378 C  CB  . LEU B 1 375 ? 139.859 99.183  133.106 1.00 31.71  ? 375 LEU B CB  1 
ATOM   6379 C  CG  . LEU B 1 375 ? 139.278 97.837  133.546 1.00 31.71  ? 375 LEU B CG  1 
ATOM   6380 C  CD1 . LEU B 1 375 ? 138.945 97.833  135.029 1.00 31.71  ? 375 LEU B CD1 1 
ATOM   6381 C  CD2 . LEU B 1 375 ? 138.049 97.496  132.722 1.00 31.71  ? 375 LEU B CD2 1 
ATOM   6382 N  N   . PHE B 1 376 ? 141.788 101.759 132.744 1.00 30.64  ? 376 PHE B N   1 
ATOM   6383 C  CA  . PHE B 1 376 ? 142.440 102.784 131.941 1.00 30.64  ? 376 PHE B CA  1 
ATOM   6384 C  C   . PHE B 1 376 ? 143.682 103.341 132.627 1.00 30.64  ? 376 PHE B C   1 
ATOM   6385 O  O   . PHE B 1 376 ? 143.975 104.534 132.501 1.00 30.64  ? 376 PHE B O   1 
ATOM   6386 C  CB  . PHE B 1 376 ? 141.463 103.916 131.628 1.00 30.64  ? 376 PHE B CB  1 
ATOM   6387 C  CG  . PHE B 1 376 ? 140.268 103.488 130.828 1.00 30.64  ? 376 PHE B CG  1 
ATOM   6388 C  CD1 . PHE B 1 376 ? 140.389 103.183 129.485 1.00 30.64  ? 376 PHE B CD1 1 
ATOM   6389 C  CD2 . PHE B 1 376 ? 139.020 103.400 131.418 1.00 30.64  ? 376 PHE B CD2 1 
ATOM   6390 C  CE1 . PHE B 1 376 ? 139.289 102.793 128.748 1.00 30.64  ? 376 PHE B CE1 1 
ATOM   6391 C  CE2 . PHE B 1 376 ? 137.918 103.011 130.686 1.00 30.64  ? 376 PHE B CE2 1 
ATOM   6392 C  CZ  . PHE B 1 376 ? 138.053 102.707 129.350 1.00 30.64  ? 376 PHE B CZ  1 
ATOM   6393 N  N   . SER B 1 377 ? 144.424 102.502 133.351 1.00 36.37  ? 377 SER B N   1 
ATOM   6394 C  CA  . SER B 1 377 ? 145.567 102.990 134.114 1.00 36.37  ? 377 SER B CA  1 
ATOM   6395 C  C   . SER B 1 377 ? 146.776 103.188 133.211 1.00 36.37  ? 377 SER B C   1 
ATOM   6396 O  O   . SER B 1 377 ? 147.882 102.734 133.520 1.00 36.37  ? 377 SER B O   1 
ATOM   6397 C  CB  . SER B 1 377 ? 145.907 102.027 135.253 1.00 36.37  ? 377 SER B CB  1 
ATOM   6398 O  OG  . SER B 1 377 ? 147.018 102.493 135.998 1.00 36.37  ? 377 SER B OG  1 
ATOM   6399 N  N   . GLU B 1 378 ? 146.558 103.868 132.090 1.00 40.35  ? 378 GLU B N   1 
ATOM   6400 C  CA  . GLU B 1 378 ? 147.624 104.348 131.221 1.00 40.35  ? 378 GLU B CA  1 
ATOM   6401 C  C   . GLU B 1 378 ? 147.419 105.790 130.794 1.00 40.35  ? 378 GLU B C   1 
ATOM   6402 O  O   . GLU B 1 378 ? 148.400 106.466 130.466 1.00 40.35  ? 378 GLU B O   1 
ATOM   6403 C  CB  . GLU B 1 378 ? 147.736 103.459 129.974 1.00 40.35  ? 378 GLU B CB  1 
ATOM   6404 C  CG  . GLU B 1 378 ? 148.795 103.872 128.966 1.00 40.35  ? 378 GLU B CG  1 
ATOM   6405 C  CD  . GLU B 1 378 ? 149.140 102.757 127.999 1.00 40.35  ? 378 GLU B CD  1 
ATOM   6406 O  OE1 . GLU B 1 378 ? 148.665 101.620 128.209 1.00 40.35  ? 378 GLU B OE1 1 
ATOM   6407 O  OE2 . GLU B 1 378 ? 149.883 103.016 127.029 1.00 40.35  ? 378 GLU B OE2 1 
ATOM   6408 N  N   . TYR B 1 379 ? 146.190 106.298 130.827 1.00 33.01  ? 379 TYR B N   1 
ATOM   6409 C  CA  . TYR B 1 379 ? 145.868 107.674 130.463 1.00 33.01  ? 379 TYR B CA  1 
ATOM   6410 C  C   . TYR B 1 379 ? 145.076 108.255 131.624 1.00 33.01  ? 379 TYR B C   1 
ATOM   6411 O  O   . TYR B 1 379 ? 143.843 108.355 131.564 1.00 33.01  ? 379 TYR B O   1 
ATOM   6412 C  CB  . TYR B 1 379 ? 145.079 107.723 129.155 1.00 33.01  ? 379 TYR B CB  1 
ATOM   6413 C  CG  . TYR B 1 379 ? 145.879 107.272 127.957 1.00 33.01  ? 379 TYR B CG  1 
ATOM   6414 C  CD1 . TYR B 1 379 ? 146.771 108.131 127.329 1.00 33.01  ? 379 TYR B CD1 1 
ATOM   6415 C  CD2 . TYR B 1 379 ? 145.749 105.983 127.459 1.00 33.01  ? 379 TYR B CD2 1 
ATOM   6416 C  CE1 . TYR B 1 379 ? 147.506 107.719 126.234 1.00 33.01  ? 379 TYR B CE1 1 
ATOM   6417 C  CE2 . TYR B 1 379 ? 146.479 105.562 126.367 1.00 33.01  ? 379 TYR B CE2 1 
ATOM   6418 C  CZ  . TYR B 1 379 ? 147.357 106.433 125.758 1.00 33.01  ? 379 TYR B CZ  1 
ATOM   6419 O  OH  . TYR B 1 379 ? 148.087 106.018 124.669 1.00 33.01  ? 379 TYR B OH  1 
ATOM   6420 N  N   . PRO B 1 380 ? 145.752 108.641 132.705 1.00 27.06  ? 380 PRO B N   1 
ATOM   6421 C  CA  . PRO B 1 380 ? 145.035 109.041 133.921 1.00 27.06  ? 380 PRO B CA  1 
ATOM   6422 C  C   . PRO B 1 380 ? 144.362 110.395 133.774 1.00 27.06  ? 380 PRO B C   1 
ATOM   6423 O  O   . PRO B 1 380 ? 144.923 111.338 133.210 1.00 27.06  ? 380 PRO B O   1 
ATOM   6424 C  CB  . PRO B 1 380 ? 146.135 109.080 134.988 1.00 27.06  ? 380 PRO B CB  1 
ATOM   6425 C  CG  . PRO B 1 380 ? 147.419 109.220 134.240 1.00 27.06  ? 380 PRO B CG  1 
ATOM   6426 C  CD  . PRO B 1 380 ? 147.202 108.878 132.796 1.00 27.06  ? 380 PRO B CD  1 
ATOM   6427 N  N   . GLY B 1 381 ? 143.142 110.483 134.300 1.00 23.17  ? 381 GLY B N   1 
ATOM   6428 C  CA  . GLY B 1 381 ? 142.362 111.698 134.236 1.00 23.17  ? 381 GLY B CA  1 
ATOM   6429 C  C   . GLY B 1 381 ? 141.647 111.933 132.926 1.00 23.17  ? 381 GLY B C   1 
ATOM   6430 O  O   . GLY B 1 381 ? 140.979 112.965 132.782 1.00 23.17  ? 381 GLY B O   1 
ATOM   6431 N  N   . PHE B 1 382 ? 141.767 111.017 131.964 1.00 19.73  ? 382 PHE B N   1 
ATOM   6432 C  CA  . PHE B 1 382 ? 141.136 111.220 130.666 1.00 19.73  ? 382 PHE B CA  1 
ATOM   6433 C  C   . PHE B 1 382 ? 139.625 111.046 130.754 1.00 19.73  ? 382 PHE B C   1 
ATOM   6434 O  O   . PHE B 1 382 ? 138.864 111.862 130.223 1.00 19.73  ? 382 PHE B O   1 
ATOM   6435 C  CB  . PHE B 1 382 ? 141.733 110.258 129.639 1.00 19.73  ? 382 PHE B CB  1 
ATOM   6436 C  CG  . PHE B 1 382 ? 143.050 110.713 129.074 1.00 19.73  ? 382 PHE B CG  1 
ATOM   6437 C  CD1 . PHE B 1 382 ? 144.076 111.119 129.906 1.00 19.73  ? 382 PHE B CD1 1 
ATOM   6438 C  CD2 . PHE B 1 382 ? 143.261 110.731 127.709 1.00 19.73  ? 382 PHE B CD2 1 
ATOM   6439 C  CE1 . PHE B 1 382 ? 145.284 111.533 129.387 1.00 19.73  ? 382 PHE B CE1 1 
ATOM   6440 C  CE2 . PHE B 1 382 ? 144.468 111.146 127.187 1.00 19.73  ? 382 PHE B CE2 1 
ATOM   6441 C  CZ  . PHE B 1 382 ? 145.479 111.546 128.027 1.00 19.73  ? 382 PHE B CZ  1 
ATOM   6442 N  N   . ALA B 1 383 ? 139.171 109.995 131.432 1.00 20.94  ? 383 ALA B N   1 
ATOM   6443 C  CA  . ALA B 1 383 ? 137.750 109.697 131.568 1.00 20.94  ? 383 ALA B CA  1 
ATOM   6444 C  C   . ALA B 1 383 ? 137.285 110.152 132.946 1.00 20.94  ? 383 ALA B C   1 
ATOM   6445 O  O   . ALA B 1 383 ? 137.599 109.515 133.957 1.00 20.94  ? 383 ALA B O   1 
ATOM   6446 C  CB  . ALA B 1 383 ? 137.484 108.208 131.362 1.00 20.94  ? 383 ALA B CB  1 
ATOM   6447 N  N   . THR B 1 384 ? 136.539 111.248 132.983 1.00 20.81  ? 384 THR B N   1 
ATOM   6448 C  CA  . THR B 1 384 ? 136.034 111.821 134.216 1.00 20.81  ? 384 THR B CA  1 
ATOM   6449 C  C   . THR B 1 384 ? 134.600 111.354 134.456 1.00 20.81  ? 384 THR B C   1 
ATOM   6450 O  O   . THR B 1 384 ? 134.094 110.453 133.782 1.00 20.81  ? 384 THR B O   1 
ATOM   6451 C  CB  . THR B 1 384 ? 136.133 113.346 134.162 1.00 20.81  ? 384 THR B CB  1 
ATOM   6452 O  OG1 . THR B 1 384 ? 135.432 113.829 133.011 1.00 20.81  ? 384 THR B OG1 1 
ATOM   6453 C  CG2 . THR B 1 384 ? 137.587 113.778 134.075 1.00 20.81  ? 384 THR B CG2 1 
ATOM   6454 N  N   . ASP B 1 385 ? 133.936 111.965 135.440 1.00 21.81  ? 385 ASP B N   1 
ATOM   6455 C  CA  . ASP B 1 385 ? 132.544 111.629 135.714 1.00 21.81  ? 385 ASP B CA  1 
ATOM   6456 C  C   . ASP B 1 385 ? 131.641 111.988 134.543 1.00 21.81  ? 385 ASP B C   1 
ATOM   6457 O  O   . ASP B 1 385 ? 130.616 111.332 134.322 1.00 21.81  ? 385 ASP B O   1 
ATOM   6458 C  CB  . ASP B 1 385 ? 132.069 112.345 136.979 1.00 21.81  ? 385 ASP B CB  1 
ATOM   6459 C  CG  . ASP B 1 385 ? 132.407 111.585 138.243 1.00 21.81  ? 385 ASP B CG  1 
ATOM   6460 O  OD1 . ASP B 1 385 ? 132.768 110.395 138.145 1.00 21.81  ? 385 ASP B OD1 1 
ATOM   6461 O  OD2 . ASP B 1 385 ? 132.310 112.178 139.337 1.00 21.81  ? 385 ASP B OD2 1 
ATOM   6462 N  N   . SER B 1 386 ? 132.000 113.026 133.785 1.00 17.05  ? 386 SER B N   1 
ATOM   6463 C  CA  . SER B 1 386 ? 131.166 113.442 132.665 1.00 17.05  ? 386 SER B CA  1 
ATOM   6464 C  C   . SER B 1 386 ? 131.147 112.400 131.560 1.00 17.05  ? 386 SER B C   1 
ATOM   6465 O  O   . SER B 1 386 ? 130.158 112.300 130.831 1.00 17.05  ? 386 SER B O   1 
ATOM   6466 C  CB  . SER B 1 386 ? 131.651 114.771 132.108 1.00 17.05  ? 386 SER B CB  1 
ATOM   6467 O  OG  . SER B 1 386 ? 131.533 115.802 133.069 1.00 17.05  ? 386 SER B OG  1 
ATOM   6468 N  N   . THR B 1 387 ? 132.224 111.629 131.406 1.00 15.11  ? 387 THR B N   1 
ATOM   6469 C  CA  . THR B 1 387 ? 132.195 110.533 130.446 1.00 15.11  ? 387 THR B CA  1 
ATOM   6470 C  C   . THR B 1 387 ? 131.126 109.516 130.823 1.00 15.11  ? 387 THR B C   1 
ATOM   6471 O  O   . THR B 1 387 ? 130.368 109.054 129.965 1.00 15.11  ? 387 THR B O   1 
ATOM   6472 C  CB  . THR B 1 387 ? 133.567 109.868 130.357 1.00 15.11  ? 387 THR B CB  1 
ATOM   6473 O  OG1 . THR B 1 387 ? 134.543 110.840 129.965 1.00 15.11  ? 387 THR B OG1 1 
ATOM   6474 C  CG2 . THR B 1 387 ? 133.548 108.748 129.335 1.00 15.11  ? 387 THR B CG2 1 
ATOM   6475 N  N   . VAL B 1 388 ? 131.035 109.178 132.111 1.00 14.98  ? 388 VAL B N   1 
ATOM   6476 C  CA  . VAL B 1 388 ? 129.983 108.282 132.584 1.00 14.98  ? 388 VAL B CA  1 
ATOM   6477 C  C   . VAL B 1 388 ? 128.612 108.900 132.355 1.00 14.98  ? 388 VAL B C   1 
ATOM   6478 O  O   . VAL B 1 388 ? 127.677 108.231 131.891 1.00 14.98  ? 388 VAL B O   1 
ATOM   6479 C  CB  . VAL B 1 388 ? 130.203 107.950 134.071 1.00 14.98  ? 388 VAL B CB  1 
ATOM   6480 C  CG1 . VAL B 1 388 ? 128.960 107.320 134.660 1.00 14.98  ? 388 VAL B CG1 1 
ATOM   6481 C  CG2 . VAL B 1 388 ? 131.401 107.042 134.238 1.00 14.98  ? 388 VAL B CG2 1 
ATOM   6482 N  N   . ALA B 1 389 ? 128.469 110.185 132.689 1.00 13.41  ? 389 ALA B N   1 
ATOM   6483 C  CA  . ALA B 1 389 ? 127.184 110.855 132.534 1.00 13.41  ? 389 ALA B CA  1 
ATOM   6484 C  C   . ALA B 1 389 ? 126.726 110.827 131.083 1.00 13.41  ? 389 ALA B C   1 
ATOM   6485 O  O   . ALA B 1 389 ? 125.576 110.488 130.791 1.00 13.41  ? 389 ALA B O   1 
ATOM   6486 C  CB  . ALA B 1 389 ? 127.278 112.292 133.043 1.00 13.41  ? 389 ALA B CB  1 
ATOM   6487 N  N   . LEU B 1 390 ? 127.624 111.160 130.156 1.00 11.80  ? 390 LEU B N   1 
ATOM   6488 C  CA  . LEU B 1 390 ? 127.284 111.132 128.738 1.00 11.80  ? 390 LEU B CA  1 
ATOM   6489 C  C   . LEU B 1 390 ? 126.990 109.716 128.263 1.00 11.80  ? 390 LEU B C   1 
ATOM   6490 O  O   . LEU B 1 390 ? 126.027 109.492 127.523 1.00 11.80  ? 390 LEU B O   1 
ATOM   6491 C  CB  . LEU B 1 390 ? 128.418 111.745 127.920 1.00 11.80  ? 390 LEU B CB  1 
ATOM   6492 C  CG  . LEU B 1 390 ? 128.479 113.269 127.877 1.00 11.80  ? 390 LEU B CG  1 
ATOM   6493 C  CD1 . LEU B 1 390 ? 129.658 113.719 127.044 1.00 11.80  ? 390 LEU B CD1 1 
ATOM   6494 C  CD2 . LEU B 1 390 ? 127.187 113.837 127.324 1.00 11.80  ? 390 LEU B CD2 1 
ATOM   6495 N  N   . LEU B 1 391 ? 127.801 108.742 128.688 1.00 10.97  ? 391 LEU B N   1 
ATOM   6496 C  CA  . LEU B 1 391 ? 127.621 107.369 128.231 1.00 10.97  ? 391 LEU B CA  1 
ATOM   6497 C  C   . LEU B 1 391 ? 126.261 106.822 128.639 1.00 10.97  ? 391 LEU B C   1 
ATOM   6498 O  O   . LEU B 1 391 ? 125.606 106.124 127.858 1.00 10.97  ? 391 LEU B O   1 
ATOM   6499 C  CB  . LEU B 1 391 ? 128.739 106.487 128.783 1.00 10.97  ? 391 LEU B CB  1 
ATOM   6500 C  CG  . LEU B 1 391 ? 128.645 104.988 128.501 1.00 10.97  ? 391 LEU B CG  1 
ATOM   6501 C  CD1 . LEU B 1 391 ? 128.617 104.724 127.008 1.00 10.97  ? 391 LEU B CD1 1 
ATOM   6502 C  CD2 . LEU B 1 391 ? 129.798 104.250 129.155 1.00 10.97  ? 391 LEU B CD2 1 
ATOM   6503 N  N   . ILE B 1 392 ? 125.820 107.123 129.857 1.00 12.07  ? 392 ILE B N   1 
ATOM   6504 C  CA  . ILE B 1 392 ? 124.532 106.608 130.307 1.00 12.07  ? 392 ILE B CA  1 
ATOM   6505 C  C   . ILE B 1 392 ? 123.373 107.531 129.920 1.00 12.07  ? 392 ILE B C   1 
ATOM   6506 O  O   . ILE B 1 392 ? 122.214 107.105 129.934 1.00 12.07  ? 392 ILE B O   1 
ATOM   6507 C  CB  . ILE B 1 392 ? 124.569 106.350 131.823 1.00 12.07  ? 392 ILE B CB  1 
ATOM   6508 C  CG1 . ILE B 1 392 ? 125.840 105.590 132.194 1.00 12.07  ? 392 ILE B CG1 1 
ATOM   6509 C  CG2 . ILE B 1 392 ? 123.371 105.531 132.265 1.00 12.07  ? 392 ILE B CG2 1 
ATOM   6510 C  CD1 . ILE B 1 392 ? 125.920 104.211 131.580 1.00 12.07  ? 392 ILE B CD1 1 
ATOM   6511 N  N   . GLY B 1 393 ? 123.651 108.780 129.543 1.00 13.29  ? 393 GLY B N   1 
ATOM   6512 C  CA  . GLY B 1 393 ? 122.572 109.682 129.180 1.00 13.29  ? 393 GLY B CA  1 
ATOM   6513 C  C   . GLY B 1 393 ? 122.212 109.616 127.709 1.00 13.29  ? 393 GLY B C   1 
ATOM   6514 O  O   . GLY B 1 393 ? 121.033 109.661 127.349 1.00 13.29  ? 393 GLY B O   1 
ATOM   6515 N  N   . LEU B 1 394 ? 123.217 109.514 126.837 1.00 12.40  ? 394 LEU B N   1 
ATOM   6516 C  CA  . LEU B 1 394 ? 122.950 109.403 125.410 1.00 12.40  ? 394 LEU B CA  1 
ATOM   6517 C  C   . LEU B 1 394 ? 122.236 108.106 125.059 1.00 12.40  ? 394 LEU B C   1 
ATOM   6518 O  O   . LEU B 1 394 ? 121.662 108.004 123.970 1.00 12.40  ? 394 LEU B O   1 
ATOM   6519 C  CB  . LEU B 1 394 ? 124.255 109.514 124.621 1.00 12.40  ? 394 LEU B CB  1 
ATOM   6520 C  CG  . LEU B 1 394 ? 124.998 110.846 124.737 1.00 12.40  ? 394 LEU B CG  1 
ATOM   6521 C  CD1 . LEU B 1 394 ? 126.141 110.913 123.738 1.00 12.40  ? 394 LEU B CD1 1 
ATOM   6522 C  CD2 . LEU B 1 394 ? 124.048 112.017 124.550 1.00 12.40  ? 394 LEU B CD2 1 
ATOM   6523 N  N   . LEU B 1 395 ? 122.260 107.116 125.953 1.00 10.49  ? 395 LEU B N   1 
ATOM   6524 C  CA  . LEU B 1 395 ? 121.502 105.891 125.736 1.00 10.49  ? 395 LEU B CA  1 
ATOM   6525 C  C   . LEU B 1 395 ? 120.001 106.131 125.775 1.00 10.49  ? 395 LEU B C   1 
ATOM   6526 O  O   . LEU B 1 395 ? 119.238 105.287 125.297 1.00 10.49  ? 395 LEU B O   1 
ATOM   6527 C  CB  . LEU B 1 395 ? 121.885 104.844 126.780 1.00 10.49  ? 395 LEU B CB  1 
ATOM   6528 C  CG  . LEU B 1 395 ? 123.146 104.028 126.500 1.00 10.49  ? 395 LEU B CG  1 
ATOM   6529 C  CD1 . LEU B 1 395 ? 123.218 102.833 127.432 1.00 10.49  ? 395 LEU B CD1 1 
ATOM   6530 C  CD2 . LEU B 1 395 ? 123.184 103.584 125.050 1.00 10.49  ? 395 LEU B CD2 1 
ATOM   6531 N  N   . PHE B 1 396 ? 119.560 107.255 126.343 1.00 10.49  ? 396 PHE B N   1 
ATOM   6532 C  CA  . PHE B 1 396 ? 118.140 107.575 126.363 1.00 10.49  ? 396 PHE B CA  1 
ATOM   6533 C  C   . PHE B 1 396 ? 117.622 107.981 124.992 1.00 10.49  ? 396 PHE B C   1 
ATOM   6534 O  O   . PHE B 1 396 ? 116.416 107.884 124.747 1.00 10.49  ? 396 PHE B O   1 
ATOM   6535 C  CB  . PHE B 1 396 ? 117.869 108.690 127.372 1.00 10.49  ? 396 PHE B CB  1 
ATOM   6536 C  CG  . PHE B 1 396 ? 117.960 108.245 128.801 1.00 10.49  ? 396 PHE B CG  1 
ATOM   6537 C  CD1 . PHE B 1 396 ? 116.953 107.488 129.368 1.00 10.49  ? 396 PHE B CD1 1 
ATOM   6538 C  CD2 . PHE B 1 396 ? 119.055 108.576 129.576 1.00 10.49  ? 396 PHE B CD2 1 
ATOM   6539 C  CE1 . PHE B 1 396 ? 117.033 107.075 130.679 1.00 10.49  ? 396 PHE B CE1 1 
ATOM   6540 C  CE2 . PHE B 1 396 ? 119.139 108.163 130.889 1.00 10.49  ? 396 PHE B CE2 1 
ATOM   6541 C  CZ  . PHE B 1 396 ? 118.127 107.413 131.440 1.00 10.49  ? 396 PHE B CZ  1 
ATOM   6542 N  N   . PHE B 1 397 ? 118.500 108.427 124.094 1.00 10.06  ? 397 PHE B N   1 
ATOM   6543 C  CA  . PHE B 1 397 ? 118.083 108.870 122.772 1.00 10.06  ? 397 PHE B CA  1 
ATOM   6544 C  C   . PHE B 1 397 ? 117.913 107.729 121.779 1.00 10.06  ? 397 PHE B C   1 
ATOM   6545 O  O   . PHE B 1 397 ? 117.431 107.970 120.667 1.00 10.06  ? 397 PHE B O   1 
ATOM   6546 C  CB  . PHE B 1 397 ? 119.091 109.872 122.209 1.00 10.06  ? 397 PHE B CB  1 
ATOM   6547 C  CG  . PHE B 1 397 ? 119.028 111.226 122.850 1.00 10.06  ? 397 PHE B CG  1 
ATOM   6548 C  CD1 . PHE B 1 397 ? 118.074 112.146 122.460 1.00 10.06  ? 397 PHE B CD1 1 
ATOM   6549 C  CD2 . PHE B 1 397 ? 119.934 111.586 123.829 1.00 10.06  ? 397 PHE B CD2 1 
ATOM   6550 C  CE1 . PHE B 1 397 ? 118.018 113.394 123.043 1.00 10.06  ? 397 PHE B CE1 1 
ATOM   6551 C  CE2 . PHE B 1 397 ? 119.883 112.833 124.413 1.00 10.06  ? 397 PHE B CE2 1 
ATOM   6552 C  CZ  . PHE B 1 397 ? 118.925 113.737 124.020 1.00 10.06  ? 397 PHE B CZ  1 
ATOM   6553 N  N   . LEU B 1 398 ? 118.294 106.502 122.136 1.00 13.14  ? 398 LEU B N   1 
ATOM   6554 C  CA  . LEU B 1 398 ? 118.188 105.383 121.212 1.00 13.14  ? 398 LEU B CA  1 
ATOM   6555 C  C   . LEU B 1 398 ? 117.478 104.163 121.776 1.00 13.14  ? 398 LEU B C   1 
ATOM   6556 O  O   . LEU B 1 398 ? 117.151 103.260 121.000 1.00 13.14  ? 398 LEU B O   1 
ATOM   6557 C  CB  . LEU B 1 398 ? 119.582 104.967 120.708 1.00 13.14  ? 398 LEU B CB  1 
ATOM   6558 C  CG  . LEU B 1 398 ? 120.661 104.495 121.687 1.00 13.14  ? 398 LEU B CG  1 
ATOM   6559 C  CD1 . LEU B 1 398 ? 120.557 103.008 121.984 1.00 13.14  ? 398 LEU B CD1 1 
ATOM   6560 C  CD2 . LEU B 1 398 ? 122.041 104.834 121.154 1.00 13.14  ? 398 LEU B CD2 1 
ATOM   6561 N  N   . ILE B 1 399 ? 117.233 104.097 123.076 1.00 12.61  ? 399 ILE B N   1 
ATOM   6562 C  CA  . ILE B 1 399 ? 116.506 102.960 123.645 1.00 12.61  ? 399 ILE B CA  1 
ATOM   6563 C  C   . ILE B 1 399 ? 115.029 103.097 123.288 1.00 12.61  ? 399 ILE B C   1 
ATOM   6564 O  O   . ILE B 1 399 ? 114.439 104.160 123.535 1.00 12.61  ? 399 ILE B O   1 
ATOM   6565 C  CB  . ILE B 1 399 ? 116.704 102.894 125.154 1.00 12.61  ? 399 ILE B CB  1 
ATOM   6566 C  CG1 . ILE B 1 399 ? 118.061 102.273 125.481 1.00 12.61  ? 399 ILE B CG1 1 
ATOM   6567 C  CG2 . ILE B 1 399 ? 115.598 102.083 125.799 1.00 12.61  ? 399 ILE B CG2 1 
ATOM   6568 C  CD1 . ILE B 1 399 ? 118.363 102.225 126.955 1.00 12.61  ? 399 ILE B CD1 1 
ATOM   6569 N  N   . PRO B 1 400 ? 114.412 102.077 122.695 1.00 14.25  ? 400 PRO B N   1 
ATOM   6570 C  CA  . PRO B 1 400 ? 112.995 102.185 122.329 1.00 14.25  ? 400 PRO B CA  1 
ATOM   6571 C  C   . PRO B 1 400 ? 112.108 102.369 123.551 1.00 14.25  ? 400 PRO B C   1 
ATOM   6572 O  O   . PRO B 1 400 ? 112.348 101.790 124.612 1.00 14.25  ? 400 PRO B O   1 
ATOM   6573 C  CB  . PRO B 1 400 ? 112.709 100.854 121.623 1.00 14.25  ? 400 PRO B CB  1 
ATOM   6574 C  CG  . PRO B 1 400 ? 114.045 100.339 121.213 1.00 14.25  ? 400 PRO B CG  1 
ATOM   6575 C  CD  . PRO B 1 400 ? 114.996 100.797 122.266 1.00 14.25  ? 400 PRO B CD  1 
ATOM   6576 N  N   . ALA B 1 401 ? 111.069 103.185 123.387 1.00 16.57  ? 401 ALA B N   1 
ATOM   6577 C  CA  . ALA B 1 401 ? 110.069 103.412 124.420 1.00 16.57  ? 401 ALA B CA  1 
ATOM   6578 C  C   . ALA B 1 401 ? 108.690 102.938 123.996 1.00 16.57  ? 401 ALA B C   1 
ATOM   6579 O  O   . ALA B 1 401 ? 108.038 102.199 124.741 1.00 16.57  ? 401 ALA B O   1 
ATOM   6580 C  CB  . ALA B 1 401 ? 110.022 104.901 124.791 1.00 16.57  ? 401 ALA B CB  1 
ATOM   6581 N  N   . LYS B 1 402 ? 108.227 103.344 122.817 1.00 22.12  ? 402 LYS B N   1 
ATOM   6582 C  CA  . LYS B 1 402 ? 106.945 102.902 122.293 1.00 22.12  ? 402 LYS B CA  1 
ATOM   6583 C  C   . LYS B 1 402 ? 107.064 102.677 120.793 1.00 22.12  ? 402 LYS B C   1 
ATOM   6584 O  O   . LYS B 1 402 ? 107.922 103.261 120.128 1.00 22.12  ? 402 LYS B O   1 
ATOM   6585 C  CB  . LYS B 1 402 ? 105.832 103.917 122.589 1.00 22.12  ? 402 LYS B CB  1 
ATOM   6586 C  CG  . LYS B 1 402 ? 105.319 103.865 124.018 1.00 22.12  ? 402 LYS B CG  1 
ATOM   6587 C  CD  . LYS B 1 402 ? 104.182 104.844 124.242 1.00 22.12  ? 402 LYS B CD  1 
ATOM   6588 C  CE  . LYS B 1 402 ? 103.688 104.781 125.676 1.00 22.12  ? 402 LYS B CE  1 
ATOM   6589 N  NZ  . LYS B 1 402 ? 102.589 105.750 125.929 1.00 22.12  ? 402 LYS B NZ  1 
ATOM   6590 N  N   . THR B 1 403 ? 106.191 101.822 120.270 1.00 31.93  ? 403 THR B N   1 
ATOM   6591 C  CA  . THR B 1 403 ? 106.146 101.514 118.847 1.00 31.93  ? 403 THR B CA  1 
ATOM   6592 C  C   . THR B 1 403 ? 105.034 102.330 118.201 1.00 31.93  ? 403 THR B C   1 
ATOM   6593 O  O   . THR B 1 403 ? 103.871 102.228 118.604 1.00 31.93  ? 403 THR B O   1 
ATOM   6594 C  CB  . THR B 1 403 ? 105.915 100.021 118.617 1.00 31.93  ? 403 THR B CB  1 
ATOM   6595 O  OG1 . THR B 1 403 ? 106.992 99.275  119.194 1.00 31.93  ? 403 THR B OG1 1 
ATOM   6596 C  CG2 . THR B 1 403 ? 105.837 99.719  117.132 1.00 31.93  ? 403 THR B CG2 1 
ATOM   6597 N  N   . LEU B 1 404 ? 105.391 103.132 117.203 1.00 37.03  ? 404 LEU B N   1 
ATOM   6598 C  CA  . LEU B 1 404 ? 104.420 103.973 116.514 1.00 37.03  ? 404 LEU B CA  1 
ATOM   6599 C  C   . LEU B 1 404 ? 103.456 103.130 115.689 1.00 37.03  ? 404 LEU B C   1 
ATOM   6600 O  O   . LEU B 1 404 ? 103.191 103.434 114.527 1.00 37.03  ? 404 LEU B O   1 
ATOM   6601 C  CB  . LEU B 1 404 ? 105.126 104.990 115.617 1.00 37.03  ? 404 LEU B CB  1 
ATOM   6602 C  CG  . LEU B 1 404 ? 105.558 106.307 116.263 1.00 37.03  ? 404 LEU B CG  1 
ATOM   6603 C  CD1 . LEU B 1 404 ? 106.814 106.117 117.086 1.00 37.03  ? 404 LEU B CD1 1 
ATOM   6604 C  CD2 . LEU B 1 404 ? 105.773 107.371 115.202 1.00 37.03  ? 404 LEU B CD2 1 
ATOM   6605 N  N   . GLU B 1 412 ? 100.709 98.625  118.527 1.00 103.30 ? 412 GLU B N   1 
ATOM   6606 C  CA  . GLU B 1 412 ? 101.211 97.447  117.831 1.00 103.30 ? 412 GLU B CA  1 
ATOM   6607 C  C   . GLU B 1 412 ? 100.893 97.519  116.342 1.00 103.30 ? 412 GLU B C   1 
ATOM   6608 O  O   . GLU B 1 412 ? 100.944 96.510  115.637 1.00 103.30 ? 412 GLU B O   1 
ATOM   6609 C  CB  . GLU B 1 412 ? 100.620 96.172  118.436 1.00 103.30 ? 412 GLU B CB  1 
ATOM   6610 C  CG  . GLU B 1 412 ? 101.015 95.931  119.885 1.00 103.30 ? 412 GLU B CG  1 
ATOM   6611 C  CD  . GLU B 1 412 ? 100.454 94.634  120.434 1.00 103.30 ? 412 GLU B CD  1 
ATOM   6612 O  OE1 . GLU B 1 412 ? 99.785  93.904  119.673 1.00 103.30 ? 412 GLU B OE1 1 
ATOM   6613 O  OE2 . GLU B 1 412 ? 100.679 94.347  121.629 1.00 103.30 ? 412 GLU B OE2 1 
ATOM   6614 N  N   . ILE B 1 413 ? 100.554 98.721  115.872 1.00 90.66  ? 413 ILE B N   1 
ATOM   6615 C  CA  . ILE B 1 413 ? 100.282 98.912  114.450 1.00 90.66  ? 413 ILE B CA  1 
ATOM   6616 C  C   . ILE B 1 413 ? 101.553 98.718  113.632 1.00 90.66  ? 413 ILE B C   1 
ATOM   6617 O  O   . ILE B 1 413 ? 101.511 98.187  112.515 1.00 90.66  ? 413 ILE B O   1 
ATOM   6618 C  CB  . ILE B 1 413 ? 99.652  100.296 114.207 1.00 90.66  ? 413 ILE B CB  1 
ATOM   6619 C  CG1 . ILE B 1 413 ? 100.410 101.378 114.981 1.00 90.66  ? 413 ILE B CG1 1 
ATOM   6620 C  CG2 . ILE B 1 413 ? 98.180  100.287 114.591 1.00 90.66  ? 413 ILE B CG2 1 
ATOM   6621 C  CD1 . ILE B 1 413 ? 99.914  102.781 114.712 1.00 90.66  ? 413 ILE B CD1 1 
ATOM   6622 N  N   . VAL B 1 414 ? 102.697 99.137  114.177 1.00 80.17  ? 414 VAL B N   1 
ATOM   6623 C  CA  . VAL B 1 414 ? 103.996 99.050  113.516 1.00 80.17  ? 414 VAL B CA  1 
ATOM   6624 C  C   . VAL B 1 414 ? 103.873 99.794  112.189 1.00 80.17  ? 414 VAL B C   1 
ATOM   6625 O  O   . VAL B 1 414 ? 103.972 99.204  111.107 1.00 80.17  ? 414 VAL B O   1 
ATOM   6626 C  CB  . VAL B 1 414 ? 104.445 97.584  113.342 1.00 80.17  ? 414 VAL B CB  1 
ATOM   6627 C  CG1 . VAL B 1 414 ? 105.763 97.480  112.569 1.00 80.17  ? 414 VAL B CG1 1 
ATOM   6628 C  CG2 . VAL B 1 414 ? 104.554 96.897  114.694 1.00 80.17  ? 414 VAL B CG2 1 
ATOM   6629 N  N   . ALA B 1 415 ? 103.588 101.094 112.266 1.00 68.51  ? 415 ALA B N   1 
ATOM   6630 C  CA  . ALA B 1 415 ? 103.389 101.879 111.053 1.00 68.51  ? 415 ALA B CA  1 
ATOM   6631 C  C   . ALA B 1 415 ? 104.719 102.223 110.394 1.00 68.51  ? 415 ALA B C   1 
ATOM   6632 O  O   . ALA B 1 415 ? 104.996 101.797 109.268 1.00 68.51  ? 415 ALA B O   1 
ATOM   6633 C  CB  . ALA B 1 415 ? 102.600 103.151 111.375 1.00 68.51  ? 415 ALA B CB  1 
ATOM   6634 N  N   . PHE B 1 416 ? 105.559 102.991 111.085 1.00 55.57  ? 416 PHE B N   1 
ATOM   6635 C  CA  . PHE B 1 416 ? 106.846 103.400 110.536 1.00 55.57  ? 416 PHE B CA  1 
ATOM   6636 C  C   . PHE B 1 416 ? 108.018 102.839 111.329 1.00 55.57  ? 416 PHE B C   1 
ATOM   6637 O  O   . PHE B 1 416 ? 108.861 102.142 110.757 1.00 55.57  ? 416 PHE B O   1 
ATOM   6638 C  CB  . PHE B 1 416 ? 106.919 104.931 110.477 1.00 55.57  ? 416 PHE B CB  1 
ATOM   6639 C  CG  . PHE B 1 416 ? 105.782 105.562 109.729 1.00 55.57  ? 416 PHE B CG  1 
ATOM   6640 C  CD1 . PHE B 1 416 ? 105.711 105.475 108.348 1.00 55.57  ? 416 PHE B CD1 1 
ATOM   6641 C  CD2 . PHE B 1 416 ? 104.782 106.240 110.405 1.00 55.57  ? 416 PHE B CD2 1 
ATOM   6642 C  CE1 . PHE B 1 416 ? 104.664 106.056 107.654 1.00 55.57  ? 416 PHE B CE1 1 
ATOM   6643 C  CE2 . PHE B 1 416 ? 103.732 106.822 109.718 1.00 55.57  ? 416 PHE B CE2 1 
ATOM   6644 C  CZ  . PHE B 1 416 ? 103.673 106.730 108.341 1.00 55.57  ? 416 PHE B CZ  1 
ATOM   6645 N  N   . ASP B 1 417 ? 108.091 103.109 112.624 1.00 37.21  ? 417 ASP B N   1 
ATOM   6646 C  CA  . ASP B 1 417 ? 109.249 102.756 113.440 1.00 37.21  ? 417 ASP B CA  1 
ATOM   6647 C  C   . ASP B 1 417 ? 108.862 102.928 114.904 1.00 37.21  ? 417 ASP B C   1 
ATOM   6648 O  O   . ASP B 1 417 ? 107.682 103.093 115.237 1.00 37.21  ? 417 ASP B O   1 
ATOM   6649 C  CB  . ASP B 1 417 ? 110.465 103.606 113.072 1.00 37.21  ? 417 ASP B CB  1 
ATOM   6650 C  CG  . ASP B 1 417 ? 110.234 105.083 113.312 1.00 37.21  ? 417 ASP B CG  1 
ATOM   6651 O  OD1 . ASP B 1 417 ? 109.131 105.572 112.992 1.00 37.21  ? 417 ASP B OD1 1 
ATOM   6652 O  OD2 . ASP B 1 417 ? 111.153 105.756 113.823 1.00 37.21  ? 417 ASP B OD2 1 
ATOM   6653 N  N   . TYR B 1 418 ? 109.859 102.876 115.782 1.00 25.04  ? 418 TYR B N   1 
ATOM   6654 C  CA  . TYR B 1 418 ? 109.670 103.115 117.201 1.00 25.04  ? 418 TYR B CA  1 
ATOM   6655 C  C   . TYR B 1 418 ? 109.961 104.578 117.529 1.00 25.04  ? 418 TYR B C   1 
ATOM   6656 O  O   . TYR B 1 418 ? 110.223 105.402 116.650 1.00 25.04  ? 418 TYR B O   1 
ATOM   6657 C  CB  . TYR B 1 418 ? 110.564 102.183 118.018 1.00 25.04  ? 418 TYR B CB  1 
ATOM   6658 C  CG  . TYR B 1 418 ? 112.030 102.553 117.979 1.00 25.04  ? 418 TYR B CG  1 
ATOM   6659 C  CD1 . TYR B 1 418 ? 112.832 102.192 116.907 1.00 25.04  ? 418 TYR B CD1 1 
ATOM   6660 C  CD2 . TYR B 1 418 ? 112.613 103.260 119.017 1.00 25.04  ? 418 TYR B CD2 1 
ATOM   6661 C  CE1 . TYR B 1 418 ? 114.170 102.529 116.873 1.00 25.04  ? 418 TYR B CE1 1 
ATOM   6662 C  CE2 . TYR B 1 418 ? 113.947 103.602 118.990 1.00 25.04  ? 418 TYR B CE2 1 
ATOM   6663 C  CZ  . TYR B 1 418 ? 114.720 103.234 117.918 1.00 25.04  ? 418 TYR B CZ  1 
ATOM   6664 O  OH  . TYR B 1 418 ? 116.050 103.575 117.896 1.00 25.04  ? 418 TYR B OH  1 
ATOM   6665 N  N   . SER B 1 419 ? 109.914 104.906 118.814 1.00 20.65  ? 419 SER B N   1 
ATOM   6666 C  CA  . SER B 1 419 ? 110.304 106.213 119.315 1.00 20.65  ? 419 SER B CA  1 
ATOM   6667 C  C   . SER B 1 419 ? 111.277 106.035 120.469 1.00 20.65  ? 419 SER B C   1 
ATOM   6668 O  O   . SER B 1 419 ? 111.234 105.019 121.167 1.00 20.65  ? 419 SER B O   1 
ATOM   6669 C  CB  . SER B 1 419 ? 109.085 107.019 119.783 1.00 20.65  ? 419 SER B CB  1 
ATOM   6670 O  OG  . SER B 1 419 ? 108.407 106.354 120.831 1.00 20.65  ? 419 SER B OG  1 
ATOM   6671 N  N   . PRO B 1 420 ? 112.181 106.986 120.676 1.00 14.23  ? 420 PRO B N   1 
ATOM   6672 C  CA  . PRO B 1 420 ? 113.149 106.865 121.768 1.00 14.23  ? 420 PRO B CA  1 
ATOM   6673 C  C   . PRO B 1 420 ? 112.521 107.231 123.106 1.00 14.23  ? 420 PRO B C   1 
ATOM   6674 O  O   . PRO B 1 420 ? 111.388 107.705 123.188 1.00 14.23  ? 420 PRO B O   1 
ATOM   6675 C  CB  . PRO B 1 420 ? 114.242 107.860 121.377 1.00 14.23  ? 420 PRO B CB  1 
ATOM   6676 C  CG  . PRO B 1 420 ? 113.527 108.890 120.588 1.00 14.23  ? 420 PRO B CG  1 
ATOM   6677 C  CD  . PRO B 1 420 ? 112.435 108.174 119.844 1.00 14.23  ? 420 PRO B CD  1 
ATOM   6678 N  N   . LEU B 1 421 ? 113.288 106.990 124.172 1.00 11.05  ? 421 LEU B N   1 
ATOM   6679 C  CA  . LEU B 1 421 ? 112.832 107.374 125.503 1.00 11.05  ? 421 LEU B CA  1 
ATOM   6680 C  C   . LEU B 1 421 ? 112.647 108.881 125.603 1.00 11.05  ? 421 LEU B C   1 
ATOM   6681 O  O   . LEU B 1 421 ? 111.652 109.357 126.162 1.00 11.05  ? 421 LEU B O   1 
ATOM   6682 C  CB  . LEU B 1 421 ? 113.817 106.882 126.562 1.00 11.05  ? 421 LEU B CB  1 
ATOM   6683 C  CG  . LEU B 1 421 ? 113.639 105.448 127.060 1.00 11.05  ? 421 LEU B CG  1 
ATOM   6684 C  CD1 . LEU B 1 421 ? 114.802 105.048 127.943 1.00 11.05  ? 421 LEU B CD1 1 
ATOM   6685 C  CD2 . LEU B 1 421 ? 112.328 105.294 127.804 1.00 11.05  ? 421 LEU B CD2 1 
ATOM   6686 N  N   . ILE B 1 422 ? 113.593 109.648 125.069 1.00 9.95   ? 422 ILE B N   1 
ATOM   6687 C  CA  . ILE B 1 422 ? 113.476 111.098 124.975 1.00 9.95   ? 422 ILE B CA  1 
ATOM   6688 C  C   . ILE B 1 422 ? 113.959 111.529 123.599 1.00 9.95   ? 422 ILE B C   1 
ATOM   6689 O  O   . ILE B 1 422 ? 114.945 110.998 123.079 1.00 9.95   ? 422 ILE B O   1 
ATOM   6690 C  CB  . ILE B 1 422 ? 114.271 111.823 126.082 1.00 9.95   ? 422 ILE B CB  1 
ATOM   6691 C  CG1 . ILE B 1 422 ? 115.733 111.379 126.081 1.00 9.95   ? 422 ILE B CG1 1 
ATOM   6692 C  CG2 . ILE B 1 422 ? 113.641 111.584 127.440 1.00 9.95   ? 422 ILE B CG2 1 
ATOM   6693 C  CD1 . ILE B 1 422 ? 116.616 112.212 126.973 1.00 9.95   ? 422 ILE B CD1 1 
ATOM   6694 N  N   . THR B 1 423 ? 113.253 112.480 123.002 1.00 10.90  ? 423 THR B N   1 
ATOM   6695 C  CA  . THR B 1 423 ? 113.661 113.085 121.744 1.00 10.90  ? 423 THR B CA  1 
ATOM   6696 C  C   . THR B 1 423 ? 114.449 114.359 122.017 1.00 10.90  ? 423 THR B C   1 
ATOM   6697 O  O   . THR B 1 423 ? 114.429 114.901 123.124 1.00 10.90  ? 423 THR B O   1 
ATOM   6698 C  CB  . THR B 1 423 ? 112.446 113.394 120.868 1.00 10.90  ? 423 THR B CB  1 
ATOM   6699 O  OG1 . THR B 1 423 ? 111.727 114.501 121.423 1.00 10.90  ? 423 THR B OG1 1 
ATOM   6700 C  CG2 . THR B 1 423 ? 111.526 112.190 120.793 1.00 10.90  ? 423 THR B CG2 1 
ATOM   6701 N  N   . TRP B 1 424 ? 115.159 114.833 120.992 1.00 10.79  ? 424 TRP B N   1 
ATOM   6702 C  CA  . TRP B 1 424 ? 115.920 116.066 121.162 1.00 10.79  ? 424 TRP B CA  1 
ATOM   6703 C  C   . TRP B 1 424 ? 115.009 117.269 121.350 1.00 10.79  ? 424 TRP B C   1 
ATOM   6704 O  O   . TRP B 1 424 ? 115.407 118.250 121.987 1.00 10.79  ? 424 TRP B O   1 
ATOM   6705 C  CB  . TRP B 1 424 ? 116.850 116.303 119.976 1.00 10.79  ? 424 TRP B CB  1 
ATOM   6706 C  CG  . TRP B 1 424 ? 117.669 117.537 120.162 1.00 10.79  ? 424 TRP B CG  1 
ATOM   6707 C  CD1 . TRP B 1 424 ? 117.409 118.774 119.657 1.00 10.79  ? 424 TRP B CD1 1 
ATOM   6708 C  CD2 . TRP B 1 424 ? 118.865 117.662 120.937 1.00 10.79  ? 424 TRP B CD2 1 
ATOM   6709 N  NE1 . TRP B 1 424 ? 118.375 119.661 120.059 1.00 10.79  ? 424 TRP B NE1 1 
ATOM   6710 C  CE2 . TRP B 1 424 ? 119.282 119.002 120.846 1.00 10.79  ? 424 TRP B CE2 1 
ATOM   6711 C  CE3 . TRP B 1 424 ? 119.628 116.769 121.692 1.00 10.79  ? 424 TRP B CE3 1 
ATOM   6712 C  CZ2 . TRP B 1 424 ? 120.426 119.471 121.481 1.00 10.79  ? 424 TRP B CZ2 1 
ATOM   6713 C  CZ3 . TRP B 1 424 ? 120.763 117.236 122.321 1.00 10.79  ? 424 TRP B CZ3 1 
ATOM   6714 C  CH2 . TRP B 1 424 ? 121.150 118.575 122.215 1.00 10.79  ? 424 TRP B CH2 1 
ATOM   6715 N  N   . LYS B 1 425 ? 113.794 117.220 120.802 1.00 13.34  ? 425 LYS B N   1 
ATOM   6716 C  CA  . LYS B 1 425 ? 112.848 118.309 121.017 1.00 13.34  ? 425 LYS B CA  1 
ATOM   6717 C  C   . LYS B 1 425 ? 112.524 118.460 122.496 1.00 13.34  ? 425 LYS B C   1 
ATOM   6718 O  O   . LYS B 1 425 ? 112.439 119.580 123.011 1.00 13.34  ? 425 LYS B O   1 
ATOM   6719 C  CB  . LYS B 1 425 ? 111.576 118.063 120.205 1.00 13.34  ? 425 LYS B CB  1 
ATOM   6720 C  CG  . LYS B 1 425 ? 110.581 119.214 120.214 1.00 13.34  ? 425 LYS B CG  1 
ATOM   6721 C  CD  . LYS B 1 425 ? 109.480 118.995 121.243 1.00 13.34  ? 425 LYS B CD  1 
ATOM   6722 C  CE  . LYS B 1 425 ? 108.640 117.774 120.912 1.00 13.34  ? 425 LYS B CE  1 
ATOM   6723 N  NZ  . LYS B 1 425 ? 107.614 117.516 121.960 1.00 13.34  ? 425 LYS B NZ  1 
ATOM   6724 N  N   . GLU B 1 426 ? 112.335 117.340 123.195 1.00 12.62  ? 426 GLU B N   1 
ATOM   6725 C  CA  . GLU B 1 426 ? 112.058 117.387 124.624 1.00 12.62  ? 426 GLU B CA  1 
ATOM   6726 C  C   . GLU B 1 426 ? 113.303 117.696 125.443 1.00 12.62  ? 426 GLU B C   1 
ATOM   6727 O  O   . GLU B 1 426 ? 113.188 118.217 126.556 1.00 12.62  ? 426 GLU B O   1 
ATOM   6728 C  CB  . GLU B 1 426 ? 111.444 116.066 125.082 1.00 12.62  ? 426 GLU B CB  1 
ATOM   6729 C  CG  . GLU B 1 426 ? 110.314 115.587 124.197 1.00 12.62  ? 426 GLU B CG  1 
ATOM   6730 C  CD  . GLU B 1 426 ? 109.930 114.153 124.473 1.00 12.62  ? 426 GLU B CD  1 
ATOM   6731 O  OE1 . GLU B 1 426 ? 110.529 113.246 123.861 1.00 12.62  ? 426 GLU B OE1 1 
ATOM   6732 O  OE2 . GLU B 1 426 ? 109.025 113.935 125.302 1.00 12.62  ? 426 GLU B OE2 1 
ATOM   6733 N  N   . PHE B 1 427 ? 114.490 117.370 124.930 1.00 10.18  ? 427 PHE B N   1 
ATOM   6734 C  CA  . PHE B 1 427 ? 115.714 117.692 125.653 1.00 10.18  ? 427 PHE B CA  1 
ATOM   6735 C  C   . PHE B 1 427 ? 116.085 119.163 125.535 1.00 10.18  ? 427 PHE B C   1 
ATOM   6736 O  O   . PHE B 1 427 ? 116.668 119.722 126.470 1.00 10.18  ? 427 PHE B O   1 
ATOM   6737 C  CB  . PHE B 1 427 ? 116.876 116.833 125.157 1.00 10.18  ? 427 PHE B CB  1 
ATOM   6738 C  CG  . PHE B 1 427 ? 118.198 117.202 125.764 1.00 10.18  ? 427 PHE B CG  1 
ATOM   6739 C  CD1 . PHE B 1 427 ? 118.571 116.701 126.995 1.00 10.18  ? 427 PHE B CD1 1 
ATOM   6740 C  CD2 . PHE B 1 427 ? 119.063 118.060 125.110 1.00 10.18  ? 427 PHE B CD2 1 
ATOM   6741 C  CE1 . PHE B 1 427 ? 119.780 117.043 127.555 1.00 10.18  ? 427 PHE B CE1 1 
ATOM   6742 C  CE2 . PHE B 1 427 ? 120.272 118.405 125.668 1.00 10.18  ? 427 PHE B CE2 1 
ATOM   6743 C  CZ  . PHE B 1 427 ? 120.631 117.895 126.891 1.00 10.18  ? 427 PHE B CZ  1 
ATOM   6744 N  N   . GLN B 1 428 ? 115.790 119.798 124.398 1.00 11.53  ? 428 GLN B N   1 
ATOM   6745 C  CA  . GLN B 1 428 ? 116.114 121.212 124.245 1.00 11.53  ? 428 GLN B CA  1 
ATOM   6746 C  C   . GLN B 1 428 ? 115.375 122.051 125.275 1.00 11.53  ? 428 GLN B C   1 
ATOM   6747 O  O   . GLN B 1 428 ? 115.963 122.940 125.901 1.00 11.53  ? 428 GLN B O   1 
ATOM   6748 C  CB  . GLN B 1 428 ? 115.782 121.681 122.832 1.00 11.53  ? 428 GLN B CB  1 
ATOM   6749 C  CG  . GLN B 1 428 ? 116.234 123.096 122.540 1.00 11.53  ? 428 GLN B CG  1 
ATOM   6750 C  CD  . GLN B 1 428 ? 116.774 123.252 121.141 1.00 11.53  ? 428 GLN B CD  1 
ATOM   6751 O  OE1 . GLN B 1 428 ? 117.487 122.385 120.641 1.00 11.53  ? 428 GLN B OE1 1 
ATOM   6752 N  NE2 . GLN B 1 428 ? 116.434 124.360 120.497 1.00 11.53  ? 428 GLN B NE2 1 
ATOM   6753 N  N   . SER B 1 429 ? 114.088 121.787 125.462 1.00 11.45  ? 429 SER B N   1 
ATOM   6754 C  CA  . SER B 1 429 ? 113.391 122.298 126.627 1.00 11.45  ? 429 SER B CA  1 
ATOM   6755 C  C   . SER B 1 429 ? 113.783 121.472 127.846 1.00 11.45  ? 429 SER B C   1 
ATOM   6756 O  O   . SER B 1 429 ? 114.347 120.382 127.725 1.00 11.45  ? 429 SER B O   1 
ATOM   6757 C  CB  . SER B 1 429 ? 111.879 122.265 126.414 1.00 11.45  ? 429 SER B CB  1 
ATOM   6758 O  OG  . SER B 1 429 ? 111.430 120.947 126.163 1.00 11.45  ? 429 SER B OG  1 
ATOM   6759 N  N   . PHE B 1 430 ? 113.524 122.028 129.029 1.00 15.92  ? 430 PHE B N   1 
ATOM   6760 C  CA  . PHE B 1 430 ? 113.871 121.398 130.302 1.00 15.92  ? 430 PHE B CA  1 
ATOM   6761 C  C   . PHE B 1 430 ? 115.384 121.385 130.517 1.00 15.92  ? 430 PHE B C   1 
ATOM   6762 O  O   . PHE B 1 430 ? 115.859 121.068 131.612 1.00 15.92  ? 430 PHE B O   1 
ATOM   6763 C  CB  . PHE B 1 430 ? 113.272 119.982 130.374 1.00 15.92  ? 430 PHE B CB  1 
ATOM   6764 C  CG  . PHE B 1 430 ? 113.517 119.275 131.674 1.00 15.92  ? 430 PHE B CG  1 
ATOM   6765 C  CD1 . PHE B 1 430 ? 112.636 119.415 132.728 1.00 15.92  ? 430 PHE B CD1 1 
ATOM   6766 C  CD2 . PHE B 1 430 ? 114.602 118.431 131.825 1.00 15.92  ? 430 PHE B CD2 1 
ATOM   6767 C  CE1 . PHE B 1 430 ? 112.858 118.764 133.919 1.00 15.92  ? 430 PHE B CE1 1 
ATOM   6768 C  CE2 . PHE B 1 430 ? 114.825 117.777 133.015 1.00 15.92  ? 430 PHE B CE2 1 
ATOM   6769 C  CZ  . PHE B 1 430 ? 113.951 117.940 134.062 1.00 15.92  ? 430 PHE B CZ  1 
ATOM   6770 N  N   . MET B 1 431 ? 116.146 121.780 129.506 1.00 12.91  ? 431 MET B N   1 
ATOM   6771 C  CA  . MET B 1 431 ? 117.582 121.959 129.664 1.00 12.91  ? 431 MET B CA  1 
ATOM   6772 C  C   . MET B 1 431 ? 117.874 123.335 130.248 1.00 12.91  ? 431 MET B C   1 
ATOM   6773 O  O   . MET B 1 431 ? 117.448 124.342 129.673 1.00 12.91  ? 431 MET B O   1 
ATOM   6774 C  CB  . MET B 1 431 ? 118.294 121.799 128.331 1.00 12.91  ? 431 MET B CB  1 
ATOM   6775 C  CG  . MET B 1 431 ? 119.805 121.951 128.409 1.00 12.91  ? 431 MET B CG  1 
ATOM   6776 S  SD  . MET B 1 431 ? 120.706 120.569 129.113 1.00 12.91  ? 431 MET B SD  1 
ATOM   6777 C  CE  . MET B 1 431 ? 122.134 121.424 129.764 1.00 12.91  ? 431 MET B CE  1 
ATOM   6778 N  N   . PRO B 1 432 ? 118.576 123.426 131.370 1.00 13.08  ? 432 PRO B N   1 
ATOM   6779 C  CA  . PRO B 1 432 ? 118.933 124.743 131.907 1.00 13.08  ? 432 PRO B CA  1 
ATOM   6780 C  C   . PRO B 1 432 ? 120.028 125.409 131.094 1.00 13.08  ? 432 PRO B C   1 
ATOM   6781 O  O   . PRO B 1 432 ? 121.179 125.474 131.535 1.00 13.08  ? 432 PRO B O   1 
ATOM   6782 C  CB  . PRO B 1 432 ? 119.408 124.428 133.332 1.00 13.08  ? 432 PRO B CB  1 
ATOM   6783 C  CG  . PRO B 1 432 ? 118.974 123.019 133.600 1.00 13.08  ? 432 PRO B CG  1 
ATOM   6784 C  CD  . PRO B 1 432 ? 118.975 122.342 132.276 1.00 13.08  ? 432 PRO B CD  1 
ATOM   6785 N  N   . TRP B 1 433 ? 119.687 125.897 129.899 1.00 10.40  ? 433 TRP B N   1 
ATOM   6786 C  CA  . TRP B 1 433 ? 120.664 126.628 129.102 1.00 10.40  ? 433 TRP B CA  1 
ATOM   6787 C  C   . TRP B 1 433 ? 121.116 127.895 129.812 1.00 10.40  ? 433 TRP B C   1 
ATOM   6788 O  O   . TRP B 1 433 ? 122.280 128.296 129.689 1.00 10.40  ? 433 TRP B O   1 
ATOM   6789 C  CB  . TRP B 1 433 ? 120.080 126.969 127.733 1.00 10.40  ? 433 TRP B CB  1 
ATOM   6790 C  CG  . TRP B 1 433 ? 119.653 125.781 126.928 1.00 10.40  ? 433 TRP B CG  1 
ATOM   6791 C  CD1 . TRP B 1 433 ? 118.377 125.433 126.599 1.00 10.40  ? 433 TRP B CD1 1 
ATOM   6792 C  CD2 . TRP B 1 433 ? 120.503 124.796 126.329 1.00 10.40  ? 433 TRP B CD2 1 
ATOM   6793 N  NE1 . TRP B 1 433 ? 118.377 124.288 125.842 1.00 10.40  ? 433 TRP B NE1 1 
ATOM   6794 C  CE2 . TRP B 1 433 ? 119.671 123.878 125.659 1.00 10.40  ? 433 TRP B CE2 1 
ATOM   6795 C  CE3 . TRP B 1 433 ? 121.886 124.599 126.296 1.00 10.40  ? 433 TRP B CE3 1 
ATOM   6796 C  CZ2 . TRP B 1 433 ? 120.176 122.780 124.969 1.00 10.40  ? 433 TRP B CZ2 1 
ATOM   6797 C  CZ3 . TRP B 1 433 ? 122.384 123.508 125.610 1.00 10.40  ? 433 TRP B CZ3 1 
ATOM   6798 C  CH2 . TRP B 1 433 ? 121.531 122.614 124.956 1.00 10.40  ? 433 TRP B CH2 1 
ATOM   6799 N  N   . ASP B 1 434 ? 120.215 128.534 130.561 1.00 13.06  ? 434 ASP B N   1 
ATOM   6800 C  CA  . ASP B 1 434 ? 120.593 129.712 131.333 1.00 13.06  ? 434 ASP B CA  1 
ATOM   6801 C  C   . ASP B 1 434 ? 121.640 129.368 132.383 1.00 13.06  ? 434 ASP B C   1 
ATOM   6802 O  O   . ASP B 1 434 ? 122.590 130.129 132.593 1.00 13.06  ? 434 ASP B O   1 
ATOM   6803 C  CB  . ASP B 1 434 ? 119.357 130.337 131.980 1.00 13.06  ? 434 ASP B CB  1 
ATOM   6804 C  CG  . ASP B 1 434 ? 118.539 129.337 132.773 1.00 13.06  ? 434 ASP B CG  1 
ATOM   6805 O  OD1 . ASP B 1 434 ? 119.016 128.876 133.828 1.00 13.06  ? 434 ASP B OD1 1 
ATOM   6806 O  OD2 . ASP B 1 434 ? 117.408 129.023 132.349 1.00 13.06  ? 434 ASP B OD2 1 
ATOM   6807 N  N   . ILE B 1 435 ? 121.489 128.223 133.049 1.00 13.27  ? 435 ILE B N   1 
ATOM   6808 C  CA  . ILE B 1 435 ? 122.480 127.803 134.034 1.00 13.27  ? 435 ILE B CA  1 
ATOM   6809 C  C   . ILE B 1 435 ? 123.803 127.470 133.361 1.00 13.27  ? 435 ILE B C   1 
ATOM   6810 O  O   . ILE B 1 435 ? 124.877 127.766 133.898 1.00 13.27  ? 435 ILE B O   1 
ATOM   6811 C  CB  . ILE B 1 435 ? 121.944 126.623 134.860 1.00 13.27  ? 435 ILE B CB  1 
ATOM   6812 C  CG1 . ILE B 1 435 ? 120.779 127.092 135.726 1.00 13.27  ? 435 ILE B CG1 1 
ATOM   6813 C  CG2 . ILE B 1 435 ? 123.039 126.012 135.711 1.00 13.27  ? 435 ILE B CG2 1 
ATOM   6814 C  CD1 . ILE B 1 435 ? 121.154 128.175 136.712 1.00 13.27  ? 435 ILE B CD1 1 
ATOM   6815 N  N   . ALA B 1 436 ? 123.756 126.848 132.182 1.00 11.78  ? 436 ALA B N   1 
ATOM   6816 C  CA  . ALA B 1 436 ? 124.989 126.580 131.452 1.00 11.78  ? 436 ALA B CA  1 
ATOM   6817 C  C   . ALA B 1 436 ? 125.716 127.876 131.120 1.00 11.78  ? 436 ALA B C   1 
ATOM   6818 O  O   . ALA B 1 436 ? 126.933 127.981 131.315 1.00 11.78  ? 436 ALA B O   1 
ATOM   6819 C  CB  . ALA B 1 436 ? 124.687 125.790 130.181 1.00 11.78  ? 436 ALA B CB  1 
ATOM   6820 N  N   . ILE B 1 437 ? 124.979 128.884 130.650 1.00 10.31  ? 437 ILE B N   1 
ATOM   6821 C  CA  . ILE B 1 437 ? 125.587 130.175 130.339 1.00 10.31  ? 437 ILE B CA  1 
ATOM   6822 C  C   . ILE B 1 437 ? 126.142 130.827 131.600 1.00 10.31  ? 437 ILE B C   1 
ATOM   6823 O  O   . ILE B 1 437 ? 127.228 131.414 131.583 1.00 10.31  ? 437 ILE B O   1 
ATOM   6824 C  CB  . ILE B 1 437 ? 124.568 131.088 129.631 1.00 10.31  ? 437 ILE B CB  1 
ATOM   6825 C  CG1 . ILE B 1 437 ? 124.184 130.510 128.270 1.00 10.31  ? 437 ILE B CG1 1 
ATOM   6826 C  CG2 . ILE B 1 437 ? 125.128 132.489 129.464 1.00 10.31  ? 437 ILE B CG2 1 
ATOM   6827 C  CD1 . ILE B 1 437 ? 125.316 130.497 127.274 1.00 10.31  ? 437 ILE B CD1 1 
ATOM   6828 N  N   . LEU B 1 438 ? 125.407 130.738 132.710 1.00 12.23  ? 438 LEU B N   1 
ATOM   6829 C  CA  . LEU B 1 438 ? 125.845 131.370 133.952 1.00 12.23  ? 438 LEU B CA  1 
ATOM   6830 C  C   . LEU B 1 438 ? 127.131 130.737 134.474 1.00 12.23  ? 438 LEU B C   1 
ATOM   6831 O  O   . LEU B 1 438 ? 128.069 131.439 134.874 1.00 12.23  ? 438 LEU B O   1 
ATOM   6832 C  CB  . LEU B 1 438 ? 124.733 131.277 134.996 1.00 12.23  ? 438 LEU B CB  1 
ATOM   6833 C  CG  . LEU B 1 438 ? 125.015 131.834 136.390 1.00 12.23  ? 438 LEU B CG  1 
ATOM   6834 C  CD1 . LEU B 1 438 ? 125.389 133.301 136.317 1.00 12.23  ? 438 LEU B CD1 1 
ATOM   6835 C  CD2 . LEU B 1 438 ? 123.809 131.632 137.286 1.00 12.23  ? 438 LEU B CD2 1 
ATOM   6836 N  N   . VAL B 1 439 ? 127.196 129.406 134.470 1.00 14.09  ? 439 VAL B N   1 
ATOM   6837 C  CA  . VAL B 1 439 ? 128.395 128.727 134.946 1.00 14.09  ? 439 VAL B CA  1 
ATOM   6838 C  C   . VAL B 1 439 ? 129.560 128.971 133.997 1.00 14.09  ? 439 VAL B C   1 
ATOM   6839 O  O   . VAL B 1 439 ? 130.708 129.121 134.432 1.00 14.09  ? 439 VAL B O   1 
ATOM   6840 C  CB  . VAL B 1 439 ? 128.121 127.227 135.146 1.00 14.09  ? 439 VAL B CB  1 
ATOM   6841 C  CG1 . VAL B 1 439 ? 129.360 126.538 135.668 1.00 14.09  ? 439 VAL B CG1 1 
ATOM   6842 C  CG2 . VAL B 1 439 ? 126.976 127.032 136.118 1.00 14.09  ? 439 VAL B CG2 1 
ATOM   6843 N  N   . GLY B 1 440 ? 129.293 129.022 132.690 1.00 12.89  ? 440 GLY B N   1 
ATOM   6844 C  CA  . GLY B 1 440 ? 130.344 129.380 131.753 1.00 12.89  ? 440 GLY B CA  1 
ATOM   6845 C  C   . GLY B 1 440 ? 130.881 130.777 131.993 1.00 12.89  ? 440 GLY B C   1 
ATOM   6846 O  O   . GLY B 1 440 ? 132.088 131.012 131.905 1.00 12.89  ? 440 GLY B O   1 
ATOM   6847 N  N   . GLY B 1 441 ? 129.993 131.722 132.298 1.00 11.14  ? 441 GLY B N   1 
ATOM   6848 C  CA  . GLY B 1 441 ? 130.439 133.071 132.604 1.00 11.14  ? 441 GLY B CA  1 
ATOM   6849 C  C   . GLY B 1 441 ? 131.269 133.132 133.870 1.00 11.14  ? 441 GLY B C   1 
ATOM   6850 O  O   . GLY B 1 441 ? 132.260 133.862 133.940 1.00 11.14  ? 441 GLY B O   1 
ATOM   6851 N  N   . GLY B 1 442 ? 130.875 132.368 134.889 1.00 13.02  ? 442 GLY B N   1 
ATOM   6852 C  CA  . GLY B 1 442 ? 131.690 132.290 136.092 1.00 13.02  ? 442 GLY B CA  1 
ATOM   6853 C  C   . GLY B 1 442 ? 133.061 131.697 135.830 1.00 13.02  ? 442 GLY B C   1 
ATOM   6854 O  O   . GLY B 1 442 ? 134.071 132.182 136.350 1.00 13.02  ? 442 GLY B O   1 
ATOM   6855 N  N   . PHE B 1 443 ? 133.116 130.637 135.018 1.00 13.05  ? 443 PHE B N   1 
ATOM   6856 C  CA  . PHE B 1 443 ? 134.397 130.047 134.644 1.00 13.05  ? 443 PHE B CA  1 
ATOM   6857 C  C   . PHE B 1 443 ? 135.265 131.046 133.894 1.00 13.05  ? 443 PHE B C   1 
ATOM   6858 O  O   . PHE B 1 443 ? 136.471 131.149 134.147 1.00 13.05  ? 443 PHE B O   1 
ATOM   6859 C  CB  . PHE B 1 443 ? 134.170 128.802 133.788 1.00 13.05  ? 443 PHE B CB  1 
ATOM   6860 C  CG  . PHE B 1 443 ? 133.721 127.601 134.564 1.00 13.05  ? 443 PHE B CG  1 
ATOM   6861 C  CD1 . PHE B 1 443 ? 134.081 127.439 135.889 1.00 13.05  ? 443 PHE B CD1 1 
ATOM   6862 C  CD2 . PHE B 1 443 ? 132.935 126.632 133.966 1.00 13.05  ? 443 PHE B CD2 1 
ATOM   6863 C  CE1 . PHE B 1 443 ? 133.667 126.332 136.600 1.00 13.05  ? 443 PHE B CE1 1 
ATOM   6864 C  CE2 . PHE B 1 443 ? 132.520 125.525 134.672 1.00 13.05  ? 443 PHE B CE2 1 
ATOM   6865 C  CZ  . PHE B 1 443 ? 132.884 125.375 135.990 1.00 13.05  ? 443 PHE B CZ  1 
ATOM   6866 N  N   . ALA B 1 444 ? 134.668 131.788 132.959 1.00 12.36  ? 444 ALA B N   1 
ATOM   6867 C  CA  . ALA B 1 444 ? 135.422 132.776 132.196 1.00 12.36  ? 444 ALA B CA  1 
ATOM   6868 C  C   . ALA B 1 444 ? 135.935 133.891 133.095 1.00 12.36  ? 444 ALA B C   1 
ATOM   6869 O  O   . ALA B 1 444 ? 137.063 134.365 132.925 1.00 12.36  ? 444 ALA B O   1 
ATOM   6870 C  CB  . ALA B 1 444 ? 134.556 133.345 131.075 1.00 12.36  ? 444 ALA B CB  1 
ATOM   6871 N  N   . LEU B 1 445 ? 135.119 134.326 134.057 1.00 13.28  ? 445 LEU B N   1 
ATOM   6872 C  CA  . LEU B 1 445 ? 135.561 135.359 134.986 1.00 13.28  ? 445 LEU B CA  1 
ATOM   6873 C  C   . LEU B 1 445 ? 136.713 134.866 135.853 1.00 13.28  ? 445 LEU B C   1 
ATOM   6874 O  O   . LEU B 1 445 ? 137.676 135.602 136.093 1.00 13.28  ? 445 LEU B O   1 
ATOM   6875 C  CB  . LEU B 1 445 ? 134.391 135.816 135.854 1.00 13.28  ? 445 LEU B CB  1 
ATOM   6876 C  CG  . LEU B 1 445 ? 134.622 137.086 136.667 1.00 13.28  ? 445 LEU B CG  1 
ATOM   6877 C  CD1 . LEU B 1 445 ? 135.172 138.182 135.775 1.00 13.28  ? 445 LEU B CD1 1 
ATOM   6878 C  CD2 . LEU B 1 445 ? 133.333 137.528 137.333 1.00 13.28  ? 445 LEU B CD2 1 
ATOM   6879 N  N   . ALA B 1 446 ? 136.631 133.625 136.339 1.00 15.79  ? 446 ALA B N   1 
ATOM   6880 C  CA  . ALA B 1 446 ? 137.727 133.076 137.133 1.00 15.79  ? 446 ALA B CA  1 
ATOM   6881 C  C   . ALA B 1 446 ? 139.001 132.957 136.307 1.00 15.79  ? 446 ALA B C   1 
ATOM   6882 O  O   . ALA B 1 446 ? 140.098 133.261 136.791 1.00 15.79  ? 446 ALA B O   1 
ATOM   6883 C  CB  . ALA B 1 446 ? 137.332 131.718 137.708 1.00 15.79  ? 446 ALA B CB  1 
ATOM   6884 N  N   . ASP B 1 447 ? 138.875 132.513 135.054 1.00 19.95  ? 447 ASP B N   1 
ATOM   6885 C  CA  . ASP B 1 447 ? 140.044 132.403 134.187 1.00 19.95  ? 447 ASP B CA  1 
ATOM   6886 C  C   . ASP B 1 447 ? 140.646 133.771 133.897 1.00 19.95  ? 447 ASP B C   1 
ATOM   6887 O  O   . ASP B 1 447 ? 141.870 133.913 133.823 1.00 19.95  ? 447 ASP B O   1 
ATOM   6888 C  CB  . ASP B 1 447 ? 139.669 131.691 132.888 1.00 19.95  ? 447 ASP B CB  1 
ATOM   6889 C  CG  . ASP B 1 447 ? 139.314 130.233 133.104 1.00 19.95  ? 447 ASP B CG  1 
ATOM   6890 O  OD1 . ASP B 1 447 ? 139.343 129.775 134.265 1.00 19.95  ? 447 ASP B OD1 1 
ATOM   6891 O  OD2 . ASP B 1 447 ? 139.005 129.543 132.110 1.00 19.95  ? 447 ASP B OD2 1 
ATOM   6892 N  N   . GLY B 1 448 ? 139.802 134.787 133.715 1.00 20.17  ? 448 GLY B N   1 
ATOM   6893 C  CA  . GLY B 1 448 ? 140.312 136.133 133.519 1.00 20.17  ? 448 GLY B CA  1 
ATOM   6894 C  C   . GLY B 1 448 ? 140.995 136.685 134.754 1.00 20.17  ? 448 GLY B C   1 
ATOM   6895 O  O   . GLY B 1 448 ? 141.994 137.402 134.653 1.00 20.17  ? 448 GLY B O   1 
ATOM   6896 N  N   . CYS B 1 449 ? 140.460 136.372 135.937 1.00 23.67  ? 449 CYS B N   1 
ATOM   6897 C  CA  . CYS B 1 449 ? 141.111 136.785 137.176 1.00 23.67  ? 449 CYS B CA  1 
ATOM   6898 C  C   . CYS B 1 449 ? 142.472 136.119 137.328 1.00 23.67  ? 449 CYS B C   1 
ATOM   6899 O  O   . CYS B 1 449 ? 143.435 136.756 137.768 1.00 23.67  ? 449 CYS B O   1 
ATOM   6900 C  CB  . CYS B 1 449 ? 140.221 136.464 138.376 1.00 23.67  ? 449 CYS B CB  1 
ATOM   6901 S  SG  . CYS B 1 449 ? 138.734 137.480 138.507 1.00 23.67  ? 449 CYS B SG  1 
ATOM   6902 N  N   . GLU B 1 450 ? 142.566 134.836 136.977 1.00 25.56  ? 450 GLU B N   1 
ATOM   6903 C  CA  . GLU B 1 450 ? 143.851 134.146 137.049 1.00 25.56  ? 450 GLU B CA  1 
ATOM   6904 C  C   . GLU B 1 450 ? 144.831 134.678 136.010 1.00 25.56  ? 450 GLU B C   1 
ATOM   6905 O  O   . GLU B 1 450 ? 146.025 134.807 136.300 1.00 25.56  ? 450 GLU B O   1 
ATOM   6906 C  CB  . GLU B 1 450 ? 143.623 132.631 136.912 1.00 25.56  ? 450 GLU B CB  1 
ATOM   6907 C  CG  . GLU B 1 450 ? 144.860 131.711 136.995 1.00 25.56  ? 450 GLU B CG  1 
ATOM   6908 C  CD  . GLU B 1 450 ? 145.745 131.696 135.754 1.00 25.56  ? 450 GLU B CD  1 
ATOM   6909 O  OE1 . GLU B 1 450 ? 146.767 130.978 135.772 1.00 25.56  ? 450 GLU B OE1 1 
ATOM   6910 O  OE2 . GLU B 1 450 ? 145.392 132.319 134.734 1.00 25.56  ? 450 GLU B OE2 1 
ATOM   6911 N  N   . GLU B 1 451 ? 144.352 134.981 134.801 1.00 26.21  ? 451 GLU B N   1 
ATOM   6912 C  CA  . GLU B 1 451 ? 145.240 135.423 133.729 1.00 26.21  ? 451 GLU B CA  1 
ATOM   6913 C  C   . GLU B 1 451 ? 145.916 136.741 134.080 1.00 26.21  ? 451 GLU B C   1 
ATOM   6914 O  O   . GLU B 1 451 ? 147.132 136.892 133.922 1.00 26.21  ? 451 GLU B O   1 
ATOM   6915 C  CB  . GLU B 1 451 ? 144.459 135.552 132.422 1.00 26.21  ? 451 GLU B CB  1 
ATOM   6916 C  CG  . GLU B 1 451 ? 145.286 136.024 131.238 1.00 26.21  ? 451 GLU B CG  1 
ATOM   6917 C  CD  . GLU B 1 451 ? 146.208 134.952 130.693 1.00 26.21  ? 451 GLU B CD  1 
ATOM   6918 O  OE1 . GLU B 1 451 ? 147.155 134.550 131.402 1.00 26.21  ? 451 GLU B OE1 1 
ATOM   6919 O  OE2 . GLU B 1 451 ? 145.982 134.506 129.549 1.00 26.21  ? 451 GLU B OE2 1 
ATOM   6920 N  N   . SER B 1 452 ? 145.142 137.712 134.550 1.00 25.79  ? 452 SER B N   1 
ATOM   6921 C  CA  . SER B 1 452 ? 145.731 138.937 135.055 1.00 25.79  ? 452 SER B CA  1 
ATOM   6922 C  C   . SER B 1 452 ? 146.312 138.694 136.444 1.00 25.79  ? 452 SER B C   1 
ATOM   6923 O  O   . SER B 1 452 ? 146.060 137.671 137.086 1.00 25.79  ? 452 SER B O   1 
ATOM   6924 C  CB  . SER B 1 452 ? 144.696 140.058 135.089 1.00 25.79  ? 452 SER B CB  1 
ATOM   6925 O  OG  . SER B 1 452 ? 143.501 139.628 135.714 1.00 25.79  ? 452 SER B OG  1 
ATOM   6926 N  N   . GLY B 1 453 ? 147.107 139.648 136.911 1.00 32.80  ? 453 GLY B N   1 
ATOM   6927 C  CA  . GLY B 1 453 ? 147.719 139.514 138.216 1.00 32.80  ? 453 GLY B CA  1 
ATOM   6928 C  C   . GLY B 1 453 ? 146.804 139.924 139.350 1.00 32.80  ? 453 GLY B C   1 
ATOM   6929 O  O   . GLY B 1 453 ? 147.226 140.648 140.254 1.00 32.80  ? 453 GLY B O   1 
ATOM   6930 N  N   . LEU B 1 454 ? 145.549 139.474 139.319 1.00 33.65  ? 454 LEU B N   1 
ATOM   6931 C  CA  . LEU B 1 454 ? 144.583 139.859 140.341 1.00 33.65  ? 454 LEU B CA  1 
ATOM   6932 C  C   . LEU B 1 454 ? 144.553 138.872 141.502 1.00 33.65  ? 454 LEU B C   1 
ATOM   6933 O  O   . LEU B 1 454 ? 144.717 139.268 142.659 1.00 33.65  ? 454 LEU B O   1 
ATOM   6934 C  CB  . LEU B 1 454 ? 143.186 139.992 139.730 1.00 33.65  ? 454 LEU B CB  1 
ATOM   6935 C  CG  . LEU B 1 454 ? 142.062 140.229 140.739 1.00 33.65  ? 454 LEU B CG  1 
ATOM   6936 C  CD1 . LEU B 1 454 ? 142.286 141.533 141.482 1.00 33.65  ? 454 LEU B CD1 1 
ATOM   6937 C  CD2 . LEU B 1 454 ? 140.712 140.231 140.053 1.00 33.65  ? 454 LEU B CD2 1 
ATOM   6938 N  N   . SER B 1 455 ? 144.328 137.589 141.212 1.00 37.54  ? 455 SER B N   1 
ATOM   6939 C  CA  . SER B 1 455 ? 144.363 136.579 142.265 1.00 37.54  ? 455 SER B CA  1 
ATOM   6940 C  C   . SER B 1 455 ? 145.750 136.488 142.884 1.00 37.54  ? 455 SER B C   1 
ATOM   6941 O  O   . SER B 1 455 ? 145.889 136.348 144.107 1.00 37.54  ? 455 SER B O   1 
ATOM   6942 C  CB  . SER B 1 455 ? 143.932 135.226 141.705 1.00 37.54  ? 455 SER B CB  1 
ATOM   6943 O  OG  . SER B 1 455 ? 144.785 134.824 140.648 1.00 37.54  ? 455 SER B OG  1 
ATOM   6944 N  N   . LYS B 1 456 ? 146.790 136.569 142.052 1.00 40.52  ? 456 LYS B N   1 
ATOM   6945 C  CA  . LYS B 1 456 ? 148.152 136.618 142.568 1.00 40.52  ? 456 LYS B CA  1 
ATOM   6946 C  C   . LYS B 1 456 ? 148.355 137.834 143.462 1.00 40.52  ? 456 LYS B C   1 
ATOM   6947 O  O   . LYS B 1 456 ? 149.087 137.767 144.455 1.00 40.52  ? 456 LYS B O   1 
ATOM   6948 C  CB  . LYS B 1 456 ? 149.148 136.631 141.410 1.00 40.52  ? 456 LYS B CB  1 
ATOM   6949 C  CG  . LYS B 1 456 ? 150.605 136.620 141.835 1.00 40.52  ? 456 LYS B CG  1 
ATOM   6950 C  CD  . LYS B 1 456 ? 151.528 136.590 140.629 1.00 40.52  ? 456 LYS B CD  1 
ATOM   6951 C  CE  . LYS B 1 456 ? 152.987 136.601 141.049 1.00 40.52  ? 456 LYS B CE  1 
ATOM   6952 N  NZ  . LYS B 1 456 ? 153.899 136.589 139.873 1.00 40.52  ? 456 LYS B NZ  1 
ATOM   6953 N  N   . TRP B 1 457 ? 147.713 138.956 143.128 1.00 41.24  ? 457 TRP B N   1 
ATOM   6954 C  CA  . TRP B 1 457 ? 147.822 140.152 143.958 1.00 41.24  ? 457 TRP B CA  1 
ATOM   6955 C  C   . TRP B 1 457 ? 147.241 139.910 145.345 1.00 41.24  ? 457 TRP B C   1 
ATOM   6956 O  O   . TRP B 1 457 ? 147.853 140.265 146.359 1.00 41.24  ? 457 TRP B O   1 
ATOM   6957 C  CB  . TRP B 1 457 ? 147.118 141.323 143.273 1.00 41.24  ? 457 TRP B CB  1 
ATOM   6958 C  CG  . TRP B 1 457 ? 147.267 142.631 143.976 1.00 41.24  ? 457 TRP B CG  1 
ATOM   6959 C  CD1 . TRP B 1 457 ? 148.326 143.485 143.899 1.00 41.24  ? 457 TRP B CD1 1 
ATOM   6960 C  CD2 . TRP B 1 457 ? 146.319 143.243 144.856 1.00 41.24  ? 457 TRP B CD2 1 
ATOM   6961 N  NE1 . TRP B 1 457 ? 148.099 144.590 144.682 1.00 41.24  ? 457 TRP B NE1 1 
ATOM   6962 C  CE2 . TRP B 1 457 ? 146.873 144.465 145.280 1.00 41.24  ? 457 TRP B CE2 1 
ATOM   6963 C  CE3 . TRP B 1 457 ? 145.057 142.874 145.329 1.00 41.24  ? 457 TRP B CE3 1 
ATOM   6964 C  CZ2 . TRP B 1 457 ? 146.209 145.320 146.153 1.00 41.24  ? 457 TRP B CZ2 1 
ATOM   6965 C  CZ3 . TRP B 1 457 ? 144.400 143.724 146.195 1.00 41.24  ? 457 TRP B CZ3 1 
ATOM   6966 C  CH2 . TRP B 1 457 ? 144.976 144.932 146.599 1.00 41.24  ? 457 TRP B CH2 1 
ATOM   6967 N  N   . ILE B 1 458 ? 146.062 139.288 145.409 1.00 40.20  ? 458 ILE B N   1 
ATOM   6968 C  CA  . ILE B 1 458 ? 145.441 138.996 146.699 1.00 40.20  ? 458 ILE B CA  1 
ATOM   6969 C  C   . ILE B 1 458 ? 146.293 138.011 147.489 1.00 40.20  ? 458 ILE B C   1 
ATOM   6970 O  O   . ILE B 1 458 ? 146.478 138.157 148.705 1.00 40.20  ? 458 ILE B O   1 
ATOM   6971 C  CB  . ILE B 1 458 ? 144.008 138.471 146.494 1.00 40.20  ? 458 ILE B CB  1 
ATOM   6972 C  CG1 . ILE B 1 458 ? 143.170 139.498 145.731 1.00 40.20  ? 458 ILE B CG1 1 
ATOM   6973 C  CG2 . ILE B 1 458 ? 143.363 138.150 147.828 1.00 40.20  ? 458 ILE B CG2 1 
ATOM   6974 C  CD1 . ILE B 1 458 ? 141.803 138.996 145.332 1.00 40.20  ? 458 ILE B CD1 1 
ATOM   6975 N  N   . GLY B 1 459 ? 146.829 136.995 146.811 1.00 44.72  ? 459 GLY B N   1 
ATOM   6976 C  CA  . GLY B 1 459 ? 147.685 136.040 147.495 1.00 44.72  ? 459 GLY B CA  1 
ATOM   6977 C  C   . GLY B 1 459 ? 148.948 136.671 148.050 1.00 44.72  ? 459 GLY B C   1 
ATOM   6978 O  O   . GLY B 1 459 ? 149.368 136.362 149.167 1.00 44.72  ? 459 GLY B O   1 
ATOM   6979 N  N   . ASN B 1 460 ? 149.571 137.564 147.279 1.00 48.03  ? 460 ASN B N   1 
ATOM   6980 C  CA  . ASN B 1 460 ? 150.783 138.225 147.747 1.00 48.03  ? 460 ASN B CA  1 
ATOM   6981 C  C   . ASN B 1 460 ? 150.477 139.217 148.860 1.00 48.03  ? 460 ASN B C   1 
ATOM   6982 O  O   . ASN B 1 460 ? 151.330 139.478 149.715 1.00 48.03  ? 460 ASN B O   1 
ATOM   6983 C  CB  . ASN B 1 460 ? 151.486 138.919 146.581 1.00 48.03  ? 460 ASN B CB  1 
ATOM   6984 C  CG  . ASN B 1 460 ? 152.455 138.003 145.859 1.00 48.03  ? 460 ASN B CG  1 
ATOM   6985 O  OD1 . ASN B 1 460 ? 153.271 137.326 146.485 1.00 48.03  ? 460 ASN B OD1 1 
ATOM   6986 N  ND2 . ASN B 1 460 ? 152.367 137.975 144.534 1.00 48.03  ? 460 ASN B ND2 1 
ATOM   6987 N  N   . LYS B 1 461 ? 149.274 139.797 148.856 1.00 49.29  ? 461 LYS B N   1 
ATOM   6988 C  CA  . LYS B 1 461 ? 148.865 140.638 149.977 1.00 49.29  ? 461 LYS B CA  1 
ATOM   6989 C  C   . LYS B 1 461 ? 148.638 139.814 151.236 1.00 49.29  ? 461 LYS B C   1 
ATOM   6990 O  O   . LYS B 1 461 ? 148.903 140.289 152.346 1.00 49.29  ? 461 LYS B O   1 
ATOM   6991 C  CB  . LYS B 1 461 ? 147.603 141.422 149.619 1.00 49.29  ? 461 LYS B CB  1 
ATOM   6992 C  CG  . LYS B 1 461 ? 147.830 142.530 148.607 1.00 49.29  ? 461 LYS B CG  1 
ATOM   6993 C  CD  . LYS B 1 461 ? 148.754 143.601 149.159 1.00 49.29  ? 461 LYS B CD  1 
ATOM   6994 C  CE  . LYS B 1 461 ? 148.089 144.371 150.286 1.00 49.29  ? 461 LYS B CE  1 
ATOM   6995 N  NZ  . LYS B 1 461 ? 146.891 145.118 149.811 1.00 49.29  ? 461 LYS B NZ  1 
ATOM   6996 N  N   . LEU B 1 462 ? 148.136 138.588 151.087 1.00 50.66  ? 462 LEU B N   1 
ATOM   6997 C  CA  . LEU B 1 462 ? 147.928 137.720 152.240 1.00 50.66  ? 462 LEU B CA  1 
ATOM   6998 C  C   . LEU B 1 462 ? 149.233 137.234 152.862 1.00 50.66  ? 462 LEU B C   1 
ATOM   6999 O  O   . LEU B 1 462 ? 149.257 136.934 154.060 1.00 50.66  ? 462 LEU B O   1 
ATOM   7000 C  CB  . LEU B 1 462 ? 147.073 136.514 151.842 1.00 50.66  ? 462 LEU B CB  1 
ATOM   7001 C  CG  . LEU B 1 462 ? 146.640 135.562 152.961 1.00 50.66  ? 462 LEU B CG  1 
ATOM   7002 C  CD1 . LEU B 1 462 ? 146.060 136.334 154.137 1.00 50.66  ? 462 LEU B CD1 1 
ATOM   7003 C  CD2 . LEU B 1 462 ? 145.647 134.534 152.448 1.00 50.66  ? 462 LEU B CD2 1 
ATOM   7004 N  N   . SER B 1 463 ? 150.313 137.158 152.083 1.00 54.65  ? 463 SER B N   1 
ATOM   7005 C  CA  . SER B 1 463 ? 151.550 136.553 152.576 1.00 54.65  ? 463 SER B CA  1 
ATOM   7006 C  C   . SER B 1 463 ? 152.158 137.274 153.775 1.00 54.65  ? 463 SER B C   1 
ATOM   7007 O  O   . SER B 1 463 ? 152.481 136.599 154.767 1.00 54.65  ? 463 SER B O   1 
ATOM   7008 C  CB  . SER B 1 463 ? 152.559 136.448 151.427 1.00 54.65  ? 463 SER B CB  1 
ATOM   7009 O  OG  . SER B 1 463 ? 152.107 135.545 150.433 1.00 54.65  ? 463 SER B OG  1 
ATOM   7010 N  N   . PRO B 1 464 ? 152.351 138.609 153.772 1.00 58.50  ? 464 PRO B N   1 
ATOM   7011 C  CA  . PRO B 1 464 ? 153.052 139.242 154.906 1.00 58.50  ? 464 PRO B CA  1 
ATOM   7012 C  C   . PRO B 1 464 ? 152.176 139.364 156.149 1.00 58.50  ? 464 PRO B C   1 
ATOM   7013 O  O   . PRO B 1 464 ? 151.797 140.458 156.575 1.00 58.50  ? 464 PRO B O   1 
ATOM   7014 C  CB  . PRO B 1 464 ? 153.453 140.609 154.328 1.00 58.50  ? 464 PRO B CB  1 
ATOM   7015 C  CG  . PRO B 1 464 ? 153.072 140.593 152.875 1.00 58.50  ? 464 PRO B CG  1 
ATOM   7016 C  CD  . PRO B 1 464 ? 151.979 139.608 152.761 1.00 58.50  ? 464 PRO B CD  1 
ATOM   7017 N  N   . LEU B 1 465 ? 151.848 138.217 156.745 1.00 56.30  ? 465 LEU B N   1 
ATOM   7018 C  CA  . LEU B 1 465 ? 151.133 138.157 158.014 1.00 56.30  ? 465 LEU B CA  1 
ATOM   7019 C  C   . LEU B 1 465 ? 151.877 137.279 159.013 1.00 56.30  ? 465 LEU B C   1 
ATOM   7020 O  O   . LEU B 1 465 ? 151.270 136.717 159.926 1.00 56.30  ? 465 LEU B O   1 
ATOM   7021 C  CB  . LEU B 1 465 ? 149.705 137.647 157.820 1.00 56.30  ? 465 LEU B CB  1 
ATOM   7022 C  CG  . LEU B 1 465 ? 148.710 138.576 157.124 1.00 56.30  ? 465 LEU B CG  1 
ATOM   7023 C  CD1 . LEU B 1 465 ? 147.297 138.043 157.277 1.00 56.30  ? 465 LEU B CD1 1 
ATOM   7024 C  CD2 . LEU B 1 465 ? 148.811 139.984 157.681 1.00 56.30  ? 465 LEU B CD2 1 
ATOM   7025 N  N   . GLY B 1 466 ? 153.197 137.157 158.853 1.00 61.49  ? 466 GLY B N   1 
ATOM   7026 C  CA  . GLY B 1 466 ? 153.956 136.248 159.694 1.00 61.49  ? 466 GLY B CA  1 
ATOM   7027 C  C   . GLY B 1 466 ? 154.044 136.688 161.142 1.00 61.49  ? 466 GLY B C   1 
ATOM   7028 O  O   . GLY B 1 466 ? 154.187 135.854 162.039 1.00 61.49  ? 466 GLY B O   1 
ATOM   7029 N  N   . SER B 1 467 ? 153.960 137.991 161.392 1.00 64.18  ? 467 SER B N   1 
ATOM   7030 C  CA  . SER B 1 467 ? 154.042 138.525 162.744 1.00 64.18  ? 467 SER B CA  1 
ATOM   7031 C  C   . SER B 1 467 ? 152.729 138.414 163.506 1.00 64.18  ? 467 SER B C   1 
ATOM   7032 O  O   . SER B 1 467 ? 152.708 138.664 164.716 1.00 64.18  ? 467 SER B O   1 
ATOM   7033 C  CB  . SER B 1 467 ? 154.492 139.989 162.706 1.00 64.18  ? 467 SER B CB  1 
ATOM   7034 O  OG  . SER B 1 467 ? 155.734 140.122 162.037 1.00 64.18  ? 467 SER B OG  1 
ATOM   7035 N  N   . LEU B 1 468 ? 151.640 138.050 162.835 1.00 55.68  ? 468 LEU B N   1 
ATOM   7036 C  CA  . LEU B 1 468 ? 150.359 137.920 163.499 1.00 55.68  ? 468 LEU B CA  1 
ATOM   7037 C  C   . LEU B 1 468 ? 150.301 136.626 164.309 1.00 55.68  ? 468 LEU B C   1 
ATOM   7038 O  O   . LEU B 1 468 ? 151.032 135.673 164.031 1.00 55.68  ? 468 LEU B O   1 
ATOM   7039 C  CB  . LEU B 1 468 ? 149.226 137.950 162.477 1.00 55.68  ? 468 LEU B CB  1 
ATOM   7040 C  CG  . LEU B 1 468 ? 148.480 139.276 162.329 1.00 55.68  ? 468 LEU B CG  1 
ATOM   7041 C  CD1 . LEU B 1 468 ? 149.415 140.365 161.830 1.00 55.68  ? 468 LEU B CD1 1 
ATOM   7042 C  CD2 . LEU B 1 468 ? 147.287 139.120 161.401 1.00 55.68  ? 468 LEU B CD2 1 
ATOM   7043 N  N   . PRO B 1 469 ? 149.448 136.578 165.329 1.00 54.84  ? 469 PRO B N   1 
ATOM   7044 C  CA  . PRO B 1 469 ? 149.248 135.328 166.067 1.00 54.84  ? 469 PRO B CA  1 
ATOM   7045 C  C   . PRO B 1 469 ? 148.636 134.252 165.185 1.00 54.84  ? 469 PRO B C   1 
ATOM   7046 O  O   . PRO B 1 469 ? 147.993 134.528 164.170 1.00 54.84  ? 469 PRO B O   1 
ATOM   7047 C  CB  . PRO B 1 469 ? 148.292 135.730 167.194 1.00 54.84  ? 469 PRO B CB  1 
ATOM   7048 C  CG  . PRO B 1 469 ? 148.497 137.193 167.357 1.00 54.84  ? 469 PRO B CG  1 
ATOM   7049 C  CD  . PRO B 1 469 ? 148.785 137.717 165.983 1.00 54.84  ? 469 PRO B CD  1 
ATOM   7050 N  N   . ALA B 1 470 ? 148.851 133.000 165.595 1.00 50.46  ? 470 ALA B N   1 
ATOM   7051 C  CA  . ALA B 1 470 ? 148.443 131.866 164.772 1.00 50.46  ? 470 ALA B CA  1 
ATOM   7052 C  C   . ALA B 1 470 ? 146.935 131.843 164.547 1.00 50.46  ? 470 ALA B C   1 
ATOM   7053 O  O   . ALA B 1 470 ? 146.474 131.603 163.425 1.00 50.46  ? 470 ALA B O   1 
ATOM   7054 C  CB  . ALA B 1 470 ? 148.908 130.559 165.413 1.00 50.46  ? 470 ALA B CB  1 
ATOM   7055 N  N   . TRP B 1 471 ? 146.149 132.090 165.598 1.00 53.13  ? 471 TRP B N   1 
ATOM   7056 C  CA  . TRP B 1 471 ? 144.698 132.046 165.443 1.00 53.13  ? 471 TRP B CA  1 
ATOM   7057 C  C   . TRP B 1 471 ? 144.196 133.173 164.546 1.00 53.13  ? 471 TRP B C   1 
ATOM   7058 O  O   . TRP B 1 471 ? 143.268 132.975 163.754 1.00 53.13  ? 471 TRP B O   1 
ATOM   7059 C  CB  . TRP B 1 471 ? 144.006 132.086 166.807 1.00 53.13  ? 471 TRP B CB  1 
ATOM   7060 C  CG  . TRP B 1 471 ? 144.027 133.419 167.485 1.00 53.13  ? 471 TRP B CG  1 
ATOM   7061 C  CD1 . TRP B 1 471 ? 143.088 134.404 167.386 1.00 53.13  ? 471 TRP B CD1 1 
ATOM   7062 C  CD2 . TRP B 1 471 ? 145.002 133.887 168.423 1.00 53.13  ? 471 TRP B CD2 1 
ATOM   7063 N  NE1 . TRP B 1 471 ? 143.439 135.472 168.175 1.00 53.13  ? 471 TRP B NE1 1 
ATOM   7064 C  CE2 . TRP B 1 471 ? 144.608 135.178 168.826 1.00 53.13  ? 471 TRP B CE2 1 
ATOM   7065 C  CE3 . TRP B 1 471 ? 146.178 133.346 168.952 1.00 53.13  ? 471 TRP B CE3 1 
ATOM   7066 C  CZ2 . TRP B 1 471 ? 145.347 135.937 169.731 1.00 53.13  ? 471 TRP B CZ2 1 
ATOM   7067 C  CZ3 . TRP B 1 471 ? 146.910 134.099 169.853 1.00 53.13  ? 471 TRP B CZ3 1 
ATOM   7068 C  CH2 . TRP B 1 471 ? 146.493 135.381 170.231 1.00 53.13  ? 471 TRP B CH2 1 
ATOM   7069 N  N   . LEU B 1 472 ? 144.789 134.364 164.656 1.00 51.28  ? 472 LEU B N   1 
ATOM   7070 C  CA  . LEU B 1 472 ? 144.393 135.453 163.769 1.00 51.28  ? 472 LEU B CA  1 
ATOM   7071 C  C   . LEU B 1 472 ? 144.752 135.145 162.322 1.00 51.28  ? 472 LEU B C   1 
ATOM   7072 O  O   . LEU B 1 472 ? 143.972 135.435 161.410 1.00 51.28  ? 472 LEU B O   1 
ATOM   7073 C  CB  . LEU B 1 472 ? 145.026 136.770 164.215 1.00 51.28  ? 472 LEU B CB  1 
ATOM   7074 C  CG  . LEU B 1 472 ? 144.542 137.296 165.567 1.00 51.28  ? 472 LEU B CG  1 
ATOM   7075 C  CD1 . LEU B 1 472 ? 145.323 138.528 165.985 1.00 51.28  ? 472 LEU B CD1 1 
ATOM   7076 C  CD2 . LEU B 1 472 ? 143.055 137.600 165.512 1.00 51.28  ? 472 LEU B CD2 1 
ATOM   7077 N  N   . ILE B 1 473 ? 145.929 134.557 162.090 1.00 47.51  ? 473 ILE B N   1 
ATOM   7078 C  CA  . ILE B 1 473 ? 146.292 134.145 160.736 1.00 47.51  ? 473 ILE B CA  1 
ATOM   7079 C  C   . ILE B 1 473 ? 145.285 133.136 160.210 1.00 47.51  ? 473 ILE B C   1 
ATOM   7080 O  O   . ILE B 1 473 ? 144.852 133.210 159.053 1.00 47.51  ? 473 ILE B O   1 
ATOM   7081 C  CB  . ILE B 1 473 ? 147.721 133.573 160.708 1.00 47.51  ? 473 ILE B CB  1 
ATOM   7082 C  CG1 . ILE B 1 473 ? 148.746 134.647 161.061 1.00 47.51  ? 473 ILE B CG1 1 
ATOM   7083 C  CG2 . ILE B 1 473 ? 148.032 132.979 159.344 1.00 47.51  ? 473 ILE B CG2 1 
ATOM   7084 C  CD1 . ILE B 1 473 ? 150.113 134.085 161.360 1.00 47.51  ? 473 ILE B CD1 1 
ATOM   7085 N  N   . ILE B 1 474 ? 144.893 132.182 161.055 1.00 42.69  ? 474 ILE B N   1 
ATOM   7086 C  CA  . ILE B 1 474 ? 143.933 131.162 160.646 1.00 42.69  ? 474 ILE B CA  1 
ATOM   7087 C  C   . ILE B 1 474 ? 142.606 131.806 160.270 1.00 42.69  ? 474 ILE B C   1 
ATOM   7088 O  O   . ILE B 1 474 ? 142.007 131.481 159.239 1.00 42.69  ? 474 ILE B O   1 
ATOM   7089 C  CB  . ILE B 1 474 ? 143.751 130.125 161.767 1.00 42.69  ? 474 ILE B CB  1 
ATOM   7090 C  CG1 . ILE B 1 474 ? 144.945 129.185 161.803 1.00 42.69  ? 474 ILE B CG1 1 
ATOM   7091 C  CG2 . ILE B 1 474 ? 142.493 129.319 161.538 1.00 42.69  ? 474 ILE B CG2 1 
ATOM   7092 C  CD1 . ILE B 1 474 ? 144.919 128.197 160.703 1.00 42.69  ? 474 ILE B CD1 1 
ATOM   7093 N  N   . LEU B 1 475 ? 142.130 132.730 161.105 1.00 40.82  ? 475 LEU B N   1 
ATOM   7094 C  CA  . LEU B 1 475 ? 140.847 133.375 160.850 1.00 40.82  ? 475 LEU B CA  1 
ATOM   7095 C  C   . LEU B 1 475 ? 140.885 134.204 159.572 1.00 40.82  ? 475 LEU B C   1 
ATOM   7096 O  O   . LEU B 1 475 ? 139.954 134.146 158.759 1.00 40.82  ? 475 LEU B O   1 
ATOM   7097 C  CB  . LEU B 1 475 ? 140.455 134.244 162.044 1.00 40.82  ? 475 LEU B CB  1 
ATOM   7098 C  CG  . LEU B 1 475 ? 138.978 134.605 162.176 1.00 40.82  ? 475 LEU B CG  1 
ATOM   7099 C  CD1 . LEU B 1 475 ? 138.144 133.357 162.398 1.00 40.82  ? 475 LEU B CD1 1 
ATOM   7100 C  CD2 . LEU B 1 475 ? 138.779 135.592 163.313 1.00 40.82  ? 475 LEU B CD2 1 
ATOM   7101 N  N   . ILE B 1 476 ? 141.955 134.979 159.375 1.00 39.40  ? 476 ILE B N   1 
ATOM   7102 C  CA  . ILE B 1 476 ? 142.065 135.800 158.171 1.00 39.40  ? 476 ILE B CA  1 
ATOM   7103 C  C   . ILE B 1 476 ? 142.122 134.921 156.930 1.00 39.40  ? 476 ILE B C   1 
ATOM   7104 O  O   . ILE B 1 476 ? 141.450 135.193 155.929 1.00 39.40  ? 476 ILE B O   1 
ATOM   7105 C  CB  . ILE B 1 476 ? 143.284 136.735 158.258 1.00 39.40  ? 476 ILE B CB  1 
ATOM   7106 C  CG1 . ILE B 1 476 ? 143.173 137.656 159.472 1.00 39.40  ? 476 ILE B CG1 1 
ATOM   7107 C  CG2 . ILE B 1 476 ? 143.420 137.551 156.987 1.00 39.40  ? 476 ILE B CG2 1 
ATOM   7108 C  CD1 . ILE B 1 476 ? 141.965 138.560 159.441 1.00 39.40  ? 476 ILE B CD1 1 
ATOM   7109 N  N   . SER B 1 477 ? 142.922 133.853 156.973 1.00 35.86  ? 477 SER B N   1 
ATOM   7110 C  CA  . SER B 1 477 ? 143.020 132.965 155.820 1.00 35.86  ? 477 SER B CA  1 
ATOM   7111 C  C   . SER B 1 477 ? 141.687 132.290 155.528 1.00 35.86  ? 477 SER B C   1 
ATOM   7112 O  O   . SER B 1 477 ? 141.279 132.192 154.366 1.00 35.86  ? 477 SER B O   1 
ATOM   7113 C  CB  . SER B 1 477 ? 144.108 131.920 156.051 1.00 35.86  ? 477 SER B CB  1 
ATOM   7114 O  OG  . SER B 1 477 ? 143.697 130.966 157.014 1.00 35.86  ? 477 SER B OG  1 
ATOM   7115 N  N   . SER B 1 478 ? 140.993 131.823 156.567 1.00 34.25  ? 478 SER B N   1 
ATOM   7116 C  CA  . SER B 1 478 ? 139.714 131.150 156.367 1.00 34.25  ? 478 SER B CA  1 
ATOM   7117 C  C   . SER B 1 478 ? 138.681 132.099 155.776 1.00 34.25  ? 478 SER B C   1 
ATOM   7118 O  O   . SER B 1 478 ? 137.960 131.740 154.838 1.00 34.25  ? 478 SER B O   1 
ATOM   7119 C  CB  . SER B 1 478 ? 139.220 130.568 157.691 1.00 34.25  ? 478 SER B CB  1 
ATOM   7120 O  OG  . SER B 1 478 ? 137.877 130.133 157.584 1.00 34.25  ? 478 SER B OG  1 
ATOM   7121 N  N   . LEU B 1 479 ? 138.595 133.320 156.311 1.00 33.21  ? 479 LEU B N   1 
ATOM   7122 C  CA  . LEU B 1 479 ? 137.638 134.285 155.780 1.00 33.21  ? 479 LEU B CA  1 
ATOM   7123 C  C   . LEU B 1 479 ? 137.984 134.678 154.350 1.00 33.21  ? 479 LEU B C   1 
ATOM   7124 O  O   . LEU B 1 479 ? 137.094 134.777 153.497 1.00 33.21  ? 479 LEU B O   1 
ATOM   7125 C  CB  . LEU B 1 479 ? 137.579 135.515 156.683 1.00 33.21  ? 479 LEU B CB  1 
ATOM   7126 C  CG  . LEU B 1 479 ? 136.987 135.286 158.075 1.00 33.21  ? 479 LEU B CG  1 
ATOM   7127 C  CD1 . LEU B 1 479 ? 136.630 136.606 158.738 1.00 33.21  ? 479 LEU B CD1 1 
ATOM   7128 C  CD2 . LEU B 1 479 ? 135.772 134.379 157.999 1.00 33.21  ? 479 LEU B CD2 1 
ATOM   7129 N  N   . MET B 1 480 ? 139.271 134.889 154.061 1.00 36.57  ? 480 MET B N   1 
ATOM   7130 C  CA  . MET B 1 480 ? 139.678 135.253 152.709 1.00 36.57  ? 480 MET B CA  1 
ATOM   7131 C  C   . MET B 1 480 ? 139.362 134.141 151.719 1.00 36.57  ? 480 MET B C   1 
ATOM   7132 O  O   . MET B 1 480 ? 138.893 134.406 150.607 1.00 36.57  ? 480 MET B O   1 
ATOM   7133 C  CB  . MET B 1 480 ? 141.169 135.585 152.688 1.00 36.57  ? 480 MET B CB  1 
ATOM   7134 C  CG  . MET B 1 480 ? 141.692 136.020 151.332 1.00 36.57  ? 480 MET B CG  1 
ATOM   7135 S  SD  . MET B 1 480 ? 143.172 137.040 151.461 1.00 36.57  ? 480 MET B SD  1 
ATOM   7136 C  CE  . MET B 1 480 ? 142.451 138.678 151.504 1.00 36.57  ? 480 MET B CE  1 
ATOM   7137 N  N   . VAL B 1 481 ? 139.605 132.888 152.105 1.00 30.79  ? 481 VAL B N   1 
ATOM   7138 C  CA  . VAL B 1 481 ? 139.327 131.771 151.210 1.00 30.79  ? 481 VAL B CA  1 
ATOM   7139 C  C   . VAL B 1 481 ? 137.827 131.603 151.007 1.00 30.79  ? 481 VAL B C   1 
ATOM   7140 O  O   . VAL B 1 481 ? 137.361 131.409 149.878 1.00 30.79  ? 481 VAL B O   1 
ATOM   7141 C  CB  . VAL B 1 481 ? 139.978 130.485 151.749 1.00 30.79  ? 481 VAL B CB  1 
ATOM   7142 C  CG1 . VAL B 1 481 ? 139.421 129.275 151.037 1.00 30.79  ? 481 VAL B CG1 1 
ATOM   7143 C  CG2 . VAL B 1 481 ? 141.486 130.549 151.582 1.00 30.79  ? 481 VAL B CG2 1 
ATOM   7144 N  N   . THR B 1 482 ? 137.043 131.683 152.086 1.00 31.19  ? 482 THR B N   1 
ATOM   7145 C  CA  . THR B 1 482 ? 135.603 131.493 151.967 1.00 31.19  ? 482 THR B CA  1 
ATOM   7146 C  C   . THR B 1 482 ? 134.914 132.663 151.280 1.00 31.19  ? 482 THR B C   1 
ATOM   7147 O  O   . THR B 1 482 ? 133.781 132.507 150.814 1.00 31.19  ? 482 THR B O   1 
ATOM   7148 C  CB  . THR B 1 482 ? 134.980 131.256 153.344 1.00 31.19  ? 482 THR B CB  1 
ATOM   7149 O  OG1 . THR B 1 482 ? 133.687 130.661 153.185 1.00 31.19  ? 482 THR B OG1 1 
ATOM   7150 C  CG2 . THR B 1 482 ? 134.834 132.558 154.104 1.00 31.19  ? 482 THR B CG2 1 
ATOM   7151 N  N   . SER B 1 483 ? 135.559 133.829 151.210 1.00 32.60  ? 483 SER B N   1 
ATOM   7152 C  CA  . SER B 1 483 ? 135.007 134.953 150.469 1.00 32.60  ? 483 SER B CA  1 
ATOM   7153 C  C   . SER B 1 483 ? 135.553 135.066 149.054 1.00 32.60  ? 483 SER B C   1 
ATOM   7154 O  O   . SER B 1 483 ? 134.948 135.758 148.229 1.00 32.60  ? 483 SER B O   1 
ATOM   7155 C  CB  . SER B 1 483 ? 135.274 136.265 151.215 1.00 32.60  ? 483 SER B CB  1 
ATOM   7156 O  OG  . SER B 1 483 ? 134.450 136.374 152.363 1.00 32.60  ? 483 SER B OG  1 
ATOM   7157 N  N   . LEU B 1 484 ? 136.676 134.415 148.754 1.00 29.87  ? 484 LEU B N   1 
ATOM   7158 C  CA  . LEU B 1 484 ? 137.221 134.431 147.404 1.00 29.87  ? 484 LEU B CA  1 
ATOM   7159 C  C   . LEU B 1 484 ? 136.692 133.278 146.566 1.00 29.87  ? 484 LEU B C   1 
ATOM   7160 O  O   . LEU B 1 484 ? 136.640 133.388 145.337 1.00 29.87  ? 484 LEU B O   1 
ATOM   7161 C  CB  . LEU B 1 484 ? 138.754 134.411 147.463 1.00 29.87  ? 484 LEU B CB  1 
ATOM   7162 C  CG  . LEU B 1 484 ? 139.595 134.598 146.197 1.00 29.87  ? 484 LEU B CG  1 
ATOM   7163 C  CD1 . LEU B 1 484 ? 140.936 135.184 146.583 1.00 29.87  ? 484 LEU B CD1 1 
ATOM   7164 C  CD2 . LEU B 1 484 ? 139.810 133.293 145.448 1.00 29.87  ? 484 LEU B CD2 1 
ATOM   7165 N  N   . THR B 1 485 ? 136.281 132.181 147.205 1.00 29.73  ? 485 THR B N   1 
ATOM   7166 C  CA  . THR B 1 485 ? 135.520 131.143 146.520 1.00 29.73  ? 485 THR B CA  1 
ATOM   7167 C  C   . THR B 1 485 ? 134.115 131.599 146.165 1.00 29.73  ? 485 THR B C   1 
ATOM   7168 O  O   . THR B 1 485 ? 133.344 130.815 145.603 1.00 29.73  ? 485 THR B O   1 
ATOM   7169 C  CB  . THR B 1 485 ? 135.445 129.879 147.379 1.00 29.73  ? 485 THR B CB  1 
ATOM   7170 O  OG1 . THR B 1 485 ? 134.835 128.825 146.626 1.00 29.73  ? 485 THR B OG1 1 
ATOM   7171 C  CG2 . THR B 1 485 ? 134.620 130.134 148.625 1.00 29.73  ? 485 THR B CG2 1 
ATOM   7172 N  N   . GLU B 1 486 ? 133.773 132.843 146.498 1.00 32.04  ? 486 GLU B N   1 
ATOM   7173 C  CA  . GLU B 1 486 ? 132.466 133.393 146.161 1.00 32.04  ? 486 GLU B CA  1 
ATOM   7174 C  C   . GLU B 1 486 ? 132.287 133.528 144.654 1.00 32.04  ? 486 GLU B C   1 
ATOM   7175 O  O   . GLU B 1 486 ? 131.199 133.273 144.127 1.00 32.04  ? 486 GLU B O   1 
ATOM   7176 C  CB  . GLU B 1 486 ? 132.296 134.747 146.843 1.00 32.04  ? 486 GLU B CB  1 
ATOM   7177 C  CG  . GLU B 1 486 ? 130.947 135.369 146.637 1.00 32.04  ? 486 GLU B CG  1 
ATOM   7178 C  CD  . GLU B 1 486 ? 129.848 134.515 147.203 1.00 32.04  ? 486 GLU B CD  1 
ATOM   7179 O  OE1 . GLU B 1 486 ? 130.106 133.782 148.181 1.00 32.04  ? 486 GLU B OE1 1 
ATOM   7180 O  OE2 . GLU B 1 486 ? 128.729 134.572 146.663 1.00 32.04  ? 486 GLU B OE2 1 
ATOM   7181 N  N   . VAL B 1 487 ? 133.337 133.940 143.948 1.00 30.75  ? 487 VAL B N   1 
ATOM   7182 C  CA  . VAL B 1 487 ? 133.270 134.191 142.515 1.00 30.75  ? 487 VAL B CA  1 
ATOM   7183 C  C   . VAL B 1 487 ? 134.123 133.224 141.717 1.00 30.75  ? 487 VAL B C   1 
ATOM   7184 O  O   . VAL B 1 487 ? 134.126 133.294 140.479 1.00 30.75  ? 487 VAL B O   1 
ATOM   7185 C  CB  . VAL B 1 487 ? 133.664 135.642 142.188 1.00 30.75  ? 487 VAL B CB  1 
ATOM   7186 C  CG1 . VAL B 1 487 ? 132.697 136.610 142.846 1.00 30.75  ? 487 VAL B CG1 1 
ATOM   7187 C  CG2 . VAL B 1 487 ? 135.084 135.913 142.651 1.00 30.75  ? 487 VAL B CG2 1 
ATOM   7188 N  N   . ALA B 1 488 ? 134.845 132.325 142.377 1.00 30.21  ? 488 ALA B N   1 
ATOM   7189 C  CA  . ALA B 1 488 ? 135.713 131.374 141.704 1.00 30.21  ? 488 ALA B CA  1 
ATOM   7190 C  C   . ALA B 1 488 ? 135.364 129.964 142.151 1.00 30.21  ? 488 ALA B C   1 
ATOM   7191 O  O   . ALA B 1 488 ? 134.836 129.755 143.246 1.00 30.21  ? 488 ALA B O   1 
ATOM   7192 C  CB  . ALA B 1 488 ? 137.192 131.658 141.992 1.00 30.21  ? 488 ALA B CB  1 
ATOM   7193 N  N   . SER B 1 489 ? 135.660 128.999 141.287 1.00 29.22  ? 489 SER B N   1 
ATOM   7194 C  CA  . SER B 1 489 ? 135.410 127.605 141.614 1.00 29.22  ? 489 SER B CA  1 
ATOM   7195 C  C   . SER B 1 489 ? 136.291 127.166 142.776 1.00 29.22  ? 489 SER B C   1 
ATOM   7196 O  O   . SER B 1 489 ? 137.394 127.679 142.980 1.00 29.22  ? 489 SER B O   1 
ATOM   7197 C  CB  . SER B 1 489 ? 135.664 126.716 140.399 1.00 29.22  ? 489 SER B CB  1 
ATOM   7198 O  OG  . SER B 1 489 ? 137.032 126.735 140.034 1.00 29.22  ? 489 SER B OG  1 
ATOM   7199 N  N   . ASN B 1 490 ? 135.782 126.210 143.551 1.00 28.38  ? 490 ASN B N   1 
ATOM   7200 C  CA  . ASN B 1 490 ? 136.532 125.704 144.698 1.00 28.38  ? 490 ASN B CA  1 
ATOM   7201 C  C   . ASN B 1 490 ? 137.890 125.128 144.311 1.00 28.38  ? 490 ASN B C   1 
ATOM   7202 O  O   . ASN B 1 490 ? 138.883 125.446 144.990 1.00 28.38  ? 490 ASN B O   1 
ATOM   7203 C  CB  . ASN B 1 490 ? 135.681 124.674 145.447 1.00 28.38  ? 490 ASN B CB  1 
ATOM   7204 C  CG  . ASN B 1 490 ? 134.311 125.203 145.805 1.00 28.38  ? 490 ASN B CG  1 
ATOM   7205 O  OD1 . ASN B 1 490 ? 133.992 126.361 145.541 1.00 28.38  ? 490 ASN B OD1 1 
ATOM   7206 N  ND2 . ASN B 1 490 ? 133.487 124.354 146.404 1.00 28.38  ? 490 ASN B ND2 1 
ATOM   7207 N  N   . PRO B 1 491 ? 138.016 124.282 143.277 1.00 28.21  ? 491 PRO B N   1 
ATOM   7208 C  CA  . PRO B 1 491 ? 139.358 123.801 142.911 1.00 28.21  ? 491 PRO B CA  1 
ATOM   7209 C  C   . PRO B 1 491 ? 140.323 124.917 142.557 1.00 28.21  ? 491 PRO B C   1 
ATOM   7210 O  O   . PRO B 1 491 ? 141.491 124.868 142.957 1.00 28.21  ? 491 PRO B O   1 
ATOM   7211 C  CB  . PRO B 1 491 ? 139.083 122.886 141.710 1.00 28.21  ? 491 PRO B CB  1 
ATOM   7212 C  CG  . PRO B 1 491 ? 137.676 122.479 141.859 1.00 28.21  ? 491 PRO B CG  1 
ATOM   7213 C  CD  . PRO B 1 491 ? 136.979 123.663 142.432 1.00 28.21  ? 491 PRO B CD  1 
ATOM   7214 N  N   . ALA B 1 492 ? 139.860 125.933 141.827 1.00 28.94  ? 492 ALA B N   1 
ATOM   7215 C  CA  . ALA B 1 492 ? 140.739 127.038 141.463 1.00 28.94  ? 492 ALA B CA  1 
ATOM   7216 C  C   . ALA B 1 492 ? 141.194 127.807 142.694 1.00 28.94  ? 492 ALA B C   1 
ATOM   7217 O  O   . ALA B 1 492 ? 142.360 128.204 142.793 1.00 28.94  ? 492 ALA B O   1 
ATOM   7218 C  CB  . ALA B 1 492 ? 140.034 127.970 140.478 1.00 28.94  ? 492 ALA B CB  1 
ATOM   7219 N  N   . THR B 1 493 ? 140.284 128.030 143.644 1.00 27.33  ? 493 THR B N   1 
ATOM   7220 C  CA  . THR B 1 493 ? 140.645 128.744 144.862 1.00 27.33  ? 493 THR B CA  1 
ATOM   7221 C  C   . THR B 1 493 ? 141.654 127.957 145.690 1.00 27.33  ? 493 THR B C   1 
ATOM   7222 O  O   . THR B 1 493 ? 142.647 128.519 146.168 1.00 27.33  ? 493 THR B O   1 
ATOM   7223 C  CB  . THR B 1 493 ? 139.394 129.037 145.687 1.00 27.33  ? 493 THR B CB  1 
ATOM   7224 O  OG1 . THR B 1 493 ? 138.445 129.746 144.882 1.00 27.33  ? 493 THR B OG1 1 
ATOM   7225 C  CG2 . THR B 1 493 ? 139.743 129.877 146.902 1.00 27.33  ? 493 THR B CG2 1 
ATOM   7226 N  N   . ILE B 1 494 ? 141.424 126.654 145.867 1.00 29.42  ? 494 ILE B N   1 
ATOM   7227 C  CA  . ILE B 1 494 ? 142.311 125.874 146.726 1.00 29.42  ? 494 ILE B CA  1 
ATOM   7228 C  C   . ILE B 1 494 ? 143.676 125.689 146.069 1.00 29.42  ? 494 ILE B C   1 
ATOM   7229 O  O   . ILE B 1 494 ? 144.717 125.774 146.736 1.00 29.42  ? 494 ILE B O   1 
ATOM   7230 C  CB  . ILE B 1 494 ? 141.657 124.532 147.110 1.00 29.42  ? 494 ILE B CB  1 
ATOM   7231 C  CG1 . ILE B 1 494 ? 142.476 123.834 148.196 1.00 29.42  ? 494 ILE B CG1 1 
ATOM   7232 C  CG2 . ILE B 1 494 ? 141.473 123.628 145.904 1.00 29.42  ? 494 ILE B CG2 1 
ATOM   7233 C  CD1 . ILE B 1 494 ? 142.539 124.603 149.493 1.00 29.42  ? 494 ILE B CD1 1 
ATOM   7234 N  N   . THR B 1 495 ? 143.700 125.451 144.752 1.00 29.24  ? 495 THR B N   1 
ATOM   7235 C  CA  . THR B 1 495 ? 144.969 125.309 144.048 1.00 29.24  ? 495 THR B CA  1 
ATOM   7236 C  C   . THR B 1 495 ? 145.752 126.613 144.078 1.00 29.24  ? 495 THR B C   1 
ATOM   7237 O  O   . THR B 1 495 ? 146.987 126.609 144.065 1.00 29.24  ? 495 THR B O   1 
ATOM   7238 C  CB  . THR B 1 495 ? 144.719 124.863 142.606 1.00 29.24  ? 495 THR B CB  1 
ATOM   7239 O  OG1 . THR B 1 495 ? 143.948 123.656 142.607 1.00 29.24  ? 495 THR B OG1 1 
ATOM   7240 C  CG2 . THR B 1 495 ? 146.030 124.608 141.884 1.00 29.24  ? 495 THR B CG2 1 
ATOM   7241 N  N   . LEU B 1 496 ? 145.046 127.742 144.114 1.00 33.24  ? 496 LEU B N   1 
ATOM   7242 C  CA  . LEU B 1 496 ? 145.714 129.031 144.239 1.00 33.24  ? 496 LEU B CA  1 
ATOM   7243 C  C   . LEU B 1 496 ? 146.284 129.219 145.639 1.00 33.24  ? 496 LEU B C   1 
ATOM   7244 O  O   . LEU B 1 496 ? 147.425 129.666 145.803 1.00 33.24  ? 496 LEU B O   1 
ATOM   7245 C  CB  . LEU B 1 496 ? 144.733 130.154 143.902 1.00 33.24  ? 496 LEU B CB  1 
ATOM   7246 C  CG  . LEU B 1 496 ? 145.077 131.566 144.376 1.00 33.24  ? 496 LEU B CG  1 
ATOM   7247 C  CD1 . LEU B 1 496 ? 146.350 132.068 143.714 1.00 33.24  ? 496 LEU B CD1 1 
ATOM   7248 C  CD2 . LEU B 1 496 ? 143.919 132.510 144.118 1.00 33.24  ? 496 LEU B CD2 1 
ATOM   7249 N  N   . PHE B 1 497 ? 145.502 128.874 146.664 1.00 35.37  ? 497 PHE B N   1 
ATOM   7250 C  CA  . PHE B 1 497 ? 145.861 129.273 148.022 1.00 35.37  ? 497 PHE B CA  1 
ATOM   7251 C  C   . PHE B 1 497 ? 146.883 128.335 148.655 1.00 35.37  ? 497 PHE B C   1 
ATOM   7252 O  O   . PHE B 1 497 ? 147.666 128.762 149.511 1.00 35.37  ? 497 PHE B O   1 
ATOM   7253 C  CB  . PHE B 1 497 ? 144.610 129.367 148.892 1.00 35.37  ? 497 PHE B CB  1 
ATOM   7254 C  CG  . PHE B 1 497 ? 143.991 130.731 148.903 1.00 35.37  ? 497 PHE B CG  1 
ATOM   7255 C  CD1 . PHE B 1 497 ? 144.456 131.706 149.767 1.00 35.37  ? 497 PHE B CD1 1 
ATOM   7256 C  CD2 . PHE B 1 497 ? 142.953 131.043 148.045 1.00 35.37  ? 497 PHE B CD2 1 
ATOM   7257 C  CE1 . PHE B 1 497 ? 143.893 132.965 149.779 1.00 35.37  ? 497 PHE B CE1 1 
ATOM   7258 C  CE2 . PHE B 1 497 ? 142.387 132.299 148.053 1.00 35.37  ? 497 PHE B CE2 1 
ATOM   7259 C  CZ  . PHE B 1 497 ? 142.858 133.262 148.922 1.00 35.37  ? 497 PHE B CZ  1 
ATOM   7260 N  N   . LEU B 1 498 ? 146.887 127.055 148.274 1.00 33.95  ? 498 LEU B N   1 
ATOM   7261 C  CA  . LEU B 1 498 ? 147.806 126.121 148.926 1.00 33.95  ? 498 LEU B CA  1 
ATOM   7262 C  C   . LEU B 1 498 ? 149.274 126.496 148.729 1.00 33.95  ? 498 LEU B C   1 
ATOM   7263 O  O   . LEU B 1 498 ? 150.017 126.522 149.728 1.00 33.95  ? 498 LEU B O   1 
ATOM   7264 C  CB  . LEU B 1 498 ? 147.513 124.690 148.459 1.00 33.95  ? 498 LEU B CB  1 
ATOM   7265 C  CG  . LEU B 1 498 ? 146.244 124.015 148.976 1.00 33.95  ? 498 LEU B CG  1 
ATOM   7266 C  CD1 . LEU B 1 498 ? 145.979 122.739 148.201 1.00 33.95  ? 498 LEU B CD1 1 
ATOM   7267 C  CD2 . LEU B 1 498 ? 146.356 123.725 150.458 1.00 33.95  ? 498 LEU B CD2 1 
ATOM   7268 N  N   . PRO B 1 499 ? 149.760 126.792 147.513 1.00 34.44  ? 499 PRO B N   1 
ATOM   7269 C  CA  . PRO B 1 499 ? 151.158 127.252 147.396 1.00 34.44  ? 499 PRO B CA  1 
ATOM   7270 C  C   . PRO B 1 499 ? 151.422 128.550 148.135 1.00 34.44  ? 499 PRO B C   1 
ATOM   7271 O  O   . PRO B 1 499 ? 152.577 128.866 148.438 1.00 34.44  ? 499 PRO B O   1 
ATOM   7272 C  CB  . PRO B 1 499 ? 151.364 127.421 145.884 1.00 34.44  ? 499 PRO B CB  1 
ATOM   7273 C  CG  . PRO B 1 499 ? 150.193 126.862 145.218 1.00 34.44  ? 499 PRO B CG  1 
ATOM   7274 C  CD  . PRO B 1 499 ? 149.181 126.427 146.209 1.00 34.44  ? 499 PRO B CD  1 
ATOM   7275 N  N   . ILE B 1 500 ? 150.381 129.340 148.390 1.00 37.70  ? 500 ILE B N   1 
ATOM   7276 C  CA  . ILE B 1 500 ? 150.557 130.588 149.126 1.00 37.70  ? 500 ILE B CA  1 
ATOM   7277 C  C   . ILE B 1 500 ? 150.669 130.311 150.619 1.00 37.70  ? 500 ILE B C   1 
ATOM   7278 O  O   . ILE B 1 500 ? 151.533 130.862 151.311 1.00 37.70  ? 500 ILE B O   1 
ATOM   7279 C  CB  . ILE B 1 500 ? 149.400 131.552 148.815 1.00 37.70  ? 500 ILE B CB  1 
ATOM   7280 C  CG1 . ILE B 1 500 ? 149.409 131.915 147.332 1.00 37.70  ? 500 ILE B CG1 1 
ATOM   7281 C  CG2 . ILE B 1 500 ? 149.500 132.800 149.671 1.00 37.70  ? 500 ILE B CG2 1 
ATOM   7282 C  CD1 . ILE B 1 500 ? 148.173 132.639 146.879 1.00 37.70  ? 500 ILE B CD1 1 
ATOM   7283 N  N   . LEU B 1 501 ? 149.795 129.445 151.136 1.00 40.09  ? 501 LEU B N   1 
ATOM   7284 C  CA  . LEU B 1 501 ? 149.736 129.222 152.576 1.00 40.09  ? 501 LEU B CA  1 
ATOM   7285 C  C   . LEU B 1 501 ? 150.879 128.341 153.065 1.00 40.09  ? 501 LEU B C   1 
ATOM   7286 O  O   . LEU B 1 501 ? 151.394 128.552 154.168 1.00 40.09  ? 501 LEU B O   1 
ATOM   7287 C  CB  . LEU B 1 501 ? 148.390 128.607 152.957 1.00 40.09  ? 501 LEU B CB  1 
ATOM   7288 C  CG  . LEU B 1 501 ? 147.161 129.494 152.760 1.00 40.09  ? 501 LEU B CG  1 
ATOM   7289 C  CD1 . LEU B 1 501 ? 145.907 128.649 152.677 1.00 40.09  ? 501 LEU B CD1 1 
ATOM   7290 C  CD2 . LEU B 1 501 ? 147.051 130.503 153.886 1.00 40.09  ? 501 LEU B CD2 1 
ATOM   7291 N  N   . SER B 1 502 ? 151.282 127.344 152.276 1.00 43.77  ? 502 SER B N   1 
ATOM   7292 C  CA  . SER B 1 502 ? 152.257 126.380 152.783 1.00 43.77  ? 502 SER B CA  1 
ATOM   7293 C  C   . SER B 1 502 ? 153.608 127.005 153.131 1.00 43.77  ? 502 SER B C   1 
ATOM   7294 O  O   . SER B 1 502 ? 154.120 126.709 154.225 1.00 43.77  ? 502 SER B O   1 
ATOM   7295 C  CB  . SER B 1 502 ? 152.407 125.219 151.791 1.00 43.77  ? 502 SER B CB  1 
ATOM   7296 O  OG  . SER B 1 502 ? 151.196 124.496 151.674 1.00 43.77  ? 502 SER B OG  1 
ATOM   7297 N  N   . PRO B 1 503 ? 154.243 127.833 152.286 1.00 45.65  ? 503 PRO B N   1 
ATOM   7298 C  CA  . PRO B 1 503 ? 155.434 128.557 152.768 1.00 45.65  ? 503 PRO B CA  1 
ATOM   7299 C  C   . PRO B 1 503 ? 155.153 129.428 153.976 1.00 45.65  ? 503 PRO B C   1 
ATOM   7300 O  O   . PRO B 1 503 ? 155.998 129.528 154.873 1.00 45.65  ? 503 PRO B O   1 
ATOM   7301 C  CB  . PRO B 1 503 ? 155.857 129.407 151.559 1.00 45.65  ? 503 PRO B CB  1 
ATOM   7302 C  CG  . PRO B 1 503 ? 154.967 129.030 150.436 1.00 45.65  ? 503 PRO B CG  1 
ATOM   7303 C  CD  . PRO B 1 503 ? 154.183 127.828 150.817 1.00 45.65  ? 503 PRO B CD  1 
ATOM   7304 N  N   . LEU B 1 504 ? 153.986 130.073 154.020 1.00 45.19  ? 504 LEU B N   1 
ATOM   7305 C  CA  . LEU B 1 504 ? 153.620 130.856 155.195 1.00 45.19  ? 504 LEU B CA  1 
ATOM   7306 C  C   . LEU B 1 504 ? 153.475 129.963 156.418 1.00 45.19  ? 504 LEU B C   1 
ATOM   7307 O  O   . LEU B 1 504 ? 153.875 130.339 157.526 1.00 45.19  ? 504 LEU B O   1 
ATOM   7308 C  CB  . LEU B 1 504 ? 152.326 131.625 154.930 1.00 45.19  ? 504 LEU B CB  1 
ATOM   7309 C  CG  . LEU B 1 504 ? 151.664 132.325 156.118 1.00 45.19  ? 504 LEU B CG  1 
ATOM   7310 C  CD1 . LEU B 1 504 ? 152.605 133.345 156.740 1.00 45.19  ? 504 LEU B CD1 1 
ATOM   7311 C  CD2 . LEU B 1 504 ? 150.364 132.983 155.689 1.00 45.19  ? 504 LEU B CD2 1 
ATOM   7312 N  N   . ALA B 1 505 ? 152.901 128.772 156.234 1.00 50.00  ? 505 ALA B N   1 
ATOM   7313 C  CA  . ALA B 1 505 ? 152.765 127.835 157.342 1.00 50.00  ? 505 ALA B CA  1 
ATOM   7314 C  C   . ALA B 1 505 ? 154.125 127.383 157.855 1.00 50.00  ? 505 ALA B C   1 
ATOM   7315 O  O   . ALA B 1 505 ? 154.327 127.261 159.067 1.00 50.00  ? 505 ALA B O   1 
ATOM   7316 C  CB  . ALA B 1 505 ? 151.929 126.632 156.909 1.00 50.00  ? 505 ALA B CB  1 
ATOM   7317 N  N   . GLU B 1 506 ? 155.067 127.118 156.947 1.00 52.87  ? 506 GLU B N   1 
ATOM   7318 C  CA  . GLU B 1 506 ? 156.386 126.645 157.356 1.00 52.87  ? 506 GLU B CA  1 
ATOM   7319 C  C   . GLU B 1 506 ? 157.281 127.763 157.874 1.00 52.87  ? 506 GLU B C   1 
ATOM   7320 O  O   . GLU B 1 506 ? 158.255 127.477 158.577 1.00 52.87  ? 506 GLU B O   1 
ATOM   7321 C  CB  . GLU B 1 506 ? 157.075 125.929 156.195 1.00 52.87  ? 506 GLU B CB  1 
ATOM   7322 C  CG  . GLU B 1 506 ? 156.319 124.717 155.681 1.00 52.87  ? 506 GLU B CG  1 
ATOM   7323 C  CD  . GLU B 1 506 ? 156.887 124.186 154.382 1.00 52.87  ? 506 GLU B CD  1 
ATOM   7324 O  OE1 . GLU B 1 506 ? 158.106 124.339 154.158 1.00 52.87  ? 506 GLU B OE1 1 
ATOM   7325 O  OE2 . GLU B 1 506 ? 156.116 123.614 153.584 1.00 52.87  ? 506 GLU B OE2 1 
ATOM   7326 N  N   . ALA B 1 507 ? 156.986 129.022 157.538 1.00 54.53  ? 507 ALA B N   1 
ATOM   7327 C  CA  . ALA B 1 507 ? 157.779 130.127 158.069 1.00 54.53  ? 507 ALA B CA  1 
ATOM   7328 C  C   . ALA B 1 507 ? 157.668 130.193 159.586 1.00 54.53  ? 507 ALA B C   1 
ATOM   7329 O  O   . ALA B 1 507 ? 158.673 130.371 160.285 1.00 54.53  ? 507 ALA B O   1 
ATOM   7330 C  CB  . ALA B 1 507 ? 157.336 131.445 157.437 1.00 54.53  ? 507 ALA B CB  1 
ATOM   7331 N  N   . ILE B 1 508 ? 156.454 130.053 160.111 1.00 60.66  ? 508 ILE B N   1 
ATOM   7332 C  CA  . ILE B 1 508 ? 156.238 129.855 161.537 1.00 60.66  ? 508 ILE B CA  1 
ATOM   7333 C  C   . ILE B 1 508 ? 156.363 128.351 161.754 1.00 60.66  ? 508 ILE B C   1 
ATOM   7334 O  O   . ILE B 1 508 ? 156.316 127.579 160.792 1.00 60.66  ? 508 ILE B O   1 
ATOM   7335 C  CB  . ILE B 1 508 ? 154.867 130.410 161.971 1.00 60.66  ? 508 ILE B CB  1 
ATOM   7336 C  CG1 . ILE B 1 508 ? 154.815 131.917 161.732 1.00 60.66  ? 508 ILE B CG1 1 
ATOM   7337 C  CG2 . ILE B 1 508 ? 154.614 130.189 163.453 1.00 60.66  ? 508 ILE B CG2 1 
ATOM   7338 C  CD1 . ILE B 1 508 ? 153.433 132.504 161.883 1.00 60.66  ? 508 ILE B CD1 1 
ATOM   7339 N  N   . HIS B 1 509 ? 156.552 127.913 162.995 1.00 64.65  ? 509 HIS B N   1 
ATOM   7340 C  CA  . HIS B 1 509 ? 156.716 126.496 163.283 1.00 64.65  ? 509 HIS B CA  1 
ATOM   7341 C  C   . HIS B 1 509 ? 155.403 125.815 163.657 1.00 64.65  ? 509 HIS B C   1 
ATOM   7342 O  O   . HIS B 1 509 ? 155.423 124.770 164.315 1.00 64.65  ? 509 HIS B O   1 
ATOM   7343 C  CB  . HIS B 1 509 ? 157.749 126.305 164.394 1.00 64.65  ? 509 HIS B CB  1 
ATOM   7344 C  CG  . HIS B 1 509 ? 159.129 126.735 164.009 1.00 64.65  ? 509 HIS B CG  1 
ATOM   7345 N  ND1 . HIS B 1 509 ? 159.576 128.029 164.164 1.00 64.65  ? 509 HIS B ND1 1 
ATOM   7346 C  CD2 . HIS B 1 509 ? 160.161 126.043 163.470 1.00 64.65  ? 509 HIS B CD2 1 
ATOM   7347 C  CE1 . HIS B 1 509 ? 160.823 128.116 163.739 1.00 64.65  ? 509 HIS B CE1 1 
ATOM   7348 N  NE2 . HIS B 1 509 ? 161.202 126.925 163.313 1.00 64.65  ? 509 HIS B NE2 1 
ATOM   7349 N  N   . VAL B 1 510 ? 154.266 126.387 163.274 1.00 55.85  ? 510 VAL B N   1 
ATOM   7350 C  CA  . VAL B 1 510 ? 152.959 125.828 163.662 1.00 55.85  ? 510 VAL B CA  1 
ATOM   7351 C  C   . VAL B 1 510 ? 152.499 124.919 162.525 1.00 55.85  ? 510 VAL B C   1 
ATOM   7352 O  O   . VAL B 1 510 ? 151.745 125.304 161.628 1.00 55.85  ? 510 VAL B O   1 
ATOM   7353 C  CB  . VAL B 1 510 ? 151.945 126.925 164.022 1.00 55.85  ? 510 VAL B CB  1 
ATOM   7354 C  CG1 . VAL B 1 510 ? 151.809 127.960 162.903 1.00 55.85  ? 510 VAL B CG1 1 
ATOM   7355 C  CG2 . VAL B 1 510 ? 150.595 126.314 164.379 1.00 55.85  ? 510 VAL B CG2 1 
ATOM   7356 N  N   . ASN B 1 511 ? 153.005 123.675 162.544 1.00 51.05  ? 511 ASN B N   1 
ATOM   7357 C  CA  . ASN B 1 511 ? 152.352 122.467 162.032 1.00 51.05  ? 511 ASN B CA  1 
ATOM   7358 C  C   . ASN B 1 511 ? 151.516 122.708 160.778 1.00 51.05  ? 511 ASN B C   1 
ATOM   7359 O  O   . ASN B 1 511 ? 150.287 122.796 160.878 1.00 51.05  ? 511 ASN B O   1 
ATOM   7360 C  CB  . ASN B 1 511 ? 151.484 121.832 163.119 1.00 51.05  ? 511 ASN B CB  1 
ATOM   7361 C  CG  . ASN B 1 511 ? 151.061 120.414 162.772 1.00 51.05  ? 511 ASN B CG  1 
ATOM   7362 O  OD1 . ASN B 1 511 ? 150.505 120.155 161.706 1.00 51.05  ? 511 ASN B OD1 1 
ATOM   7363 N  ND2 . ASN B 1 511 ? 151.339 119.482 163.675 1.00 51.05  ? 511 ASN B ND2 1 
ATOM   7364 N  N   . PRO B 1 512 ? 152.136 122.847 159.595 1.00 44.38  ? 512 PRO B N   1 
ATOM   7365 C  CA  . PRO B 1 512 ? 151.411 123.309 158.395 1.00 44.38  ? 512 PRO B CA  1 
ATOM   7366 C  C   . PRO B 1 512 ? 150.006 122.751 158.186 1.00 44.38  ? 512 PRO B C   1 
ATOM   7367 O  O   . PRO B 1 512 ? 149.175 123.420 157.562 1.00 44.38  ? 512 PRO B O   1 
ATOM   7368 C  CB  . PRO B 1 512 ? 152.336 122.879 157.246 1.00 44.38  ? 512 PRO B CB  1 
ATOM   7369 C  CG  . PRO B 1 512 ? 153.342 121.941 157.861 1.00 44.38  ? 512 PRO B CG  1 
ATOM   7370 C  CD  . PRO B 1 512 ? 153.496 122.400 159.267 1.00 44.38  ? 512 PRO B CD  1 
ATOM   7371 N  N   . LEU B 1 513 ? 149.717 121.546 158.687 1.00 42.34  ? 513 LEU B N   1 
ATOM   7372 C  CA  . LEU B 1 513 ? 148.337 121.064 158.674 1.00 42.34  ? 513 LEU B CA  1 
ATOM   7373 C  C   . LEU B 1 513 ? 147.412 122.011 159.422 1.00 42.34  ? 513 LEU B C   1 
ATOM   7374 O  O   . LEU B 1 513 ? 146.262 122.214 159.016 1.00 42.34  ? 513 LEU B O   1 
ATOM   7375 C  CB  . LEU B 1 513 ? 148.246 119.661 159.274 1.00 42.34  ? 513 LEU B CB  1 
ATOM   7376 C  CG  . LEU B 1 513 ? 148.767 118.486 158.456 1.00 42.34  ? 513 LEU B CG  1 
ATOM   7377 C  CD1 . LEU B 1 513 ? 148.784 117.229 159.297 1.00 42.34  ? 513 LEU B CD1 1 
ATOM   7378 C  CD2 . LEU B 1 513 ? 147.853 118.297 157.265 1.00 42.34  ? 513 LEU B CD2 1 
ATOM   7379 N  N   . TYR B 1 514 ? 147.903 122.610 160.511 1.00 43.29  ? 514 TYR B N   1 
ATOM   7380 C  CA  . TYR B 1 514 ? 147.073 123.488 161.328 1.00 43.29  ? 514 TYR B CA  1 
ATOM   7381 C  C   . TYR B 1 514 ? 146.494 124.633 160.512 1.00 43.29  ? 514 TYR B C   1 
ATOM   7382 O  O   . TYR B 1 514 ? 145.416 125.141 160.838 1.00 43.29  ? 514 TYR B O   1 
ATOM   7383 C  CB  . TYR B 1 514 ? 147.890 124.028 162.502 1.00 43.29  ? 514 TYR B CB  1 
ATOM   7384 C  CG  . TYR B 1 514 ? 147.124 124.914 163.456 1.00 43.29  ? 514 TYR B CG  1 
ATOM   7385 C  CD1 . TYR B 1 514 ? 146.373 124.369 164.486 1.00 43.29  ? 514 TYR B CD1 1 
ATOM   7386 C  CD2 . TYR B 1 514 ? 147.166 126.296 163.338 1.00 43.29  ? 514 TYR B CD2 1 
ATOM   7387 C  CE1 . TYR B 1 514 ? 145.677 125.174 165.365 1.00 43.29  ? 514 TYR B CE1 1 
ATOM   7388 C  CE2 . TYR B 1 514 ? 146.473 127.108 164.212 1.00 43.29  ? 514 TYR B CE2 1 
ATOM   7389 C  CZ  . TYR B 1 514 ? 145.730 126.542 165.223 1.00 43.29  ? 514 TYR B CZ  1 
ATOM   7390 O  OH  . TYR B 1 514 ? 145.038 127.346 166.098 1.00 43.29  ? 514 TYR B OH  1 
ATOM   7391 N  N   . ILE B 1 515 ? 147.179 125.042 159.448 1.00 37.68  ? 515 ILE B N   1 
ATOM   7392 C  CA  . ILE B 1 515 ? 146.693 126.126 158.601 1.00 37.68  ? 515 ILE B CA  1 
ATOM   7393 C  C   . ILE B 1 515 ? 146.093 125.601 157.304 1.00 37.68  ? 515 ILE B C   1 
ATOM   7394 O  O   . ILE B 1 515 ? 145.221 126.244 156.716 1.00 37.68  ? 515 ILE B O   1 
ATOM   7395 C  CB  . ILE B 1 515 ? 147.830 127.132 158.338 1.00 37.68  ? 515 ILE B CB  1 
ATOM   7396 C  CG1 . ILE B 1 515 ? 148.586 127.413 159.636 1.00 37.68  ? 515 ILE B CG1 1 
ATOM   7397 C  CG2 . ILE B 1 515 ? 147.285 128.420 157.747 1.00 37.68  ? 515 ILE B CG2 1 
ATOM   7398 C  CD1 . ILE B 1 515 ? 149.848 128.209 159.453 1.00 37.68  ? 515 ILE B CD1 1 
ATOM   7399 N  N   . LEU B 1 516 ? 146.532 124.431 156.838 1.00 34.73  ? 516 LEU B N   1 
ATOM   7400 C  CA  . LEU B 1 516 ? 145.992 123.902 155.591 1.00 34.73  ? 516 LEU B CA  1 
ATOM   7401 C  C   . LEU B 1 516 ? 144.580 123.356 155.775 1.00 34.73  ? 516 LEU B C   1 
ATOM   7402 O  O   . LEU B 1 516 ? 143.738 123.496 154.881 1.00 34.73  ? 516 LEU B O   1 
ATOM   7403 C  CB  . LEU B 1 516 ? 146.917 122.824 155.031 1.00 34.73  ? 516 LEU B CB  1 
ATOM   7404 C  CG  . LEU B 1 516 ? 148.273 123.315 154.522 1.00 34.73  ? 516 LEU B CG  1 
ATOM   7405 C  CD1 . LEU B 1 516 ? 149.050 122.179 153.882 1.00 34.73  ? 516 LEU B CD1 1 
ATOM   7406 C  CD2 . LEU B 1 516 ? 148.099 124.469 153.553 1.00 34.73  ? 516 LEU B CD2 1 
ATOM   7407 N  N   . ILE B 1 517 ? 144.302 122.724 156.919 1.00 31.12  ? 517 ILE B N   1 
ATOM   7408 C  CA  . ILE B 1 517 ? 142.987 122.110 157.131 1.00 31.12  ? 517 ILE B CA  1 
ATOM   7409 C  C   . ILE B 1 517 ? 141.854 123.134 157.131 1.00 31.12  ? 517 ILE B C   1 
ATOM   7410 O  O   . ILE B 1 517 ? 140.862 122.924 156.413 1.00 31.12  ? 517 ILE B O   1 
ATOM   7411 C  CB  . ILE B 1 517 ? 143.004 121.251 158.404 1.00 31.12  ? 517 ILE B CB  1 
ATOM   7412 C  CG1 . ILE B 1 517 ? 143.882 120.016 158.204 1.00 31.12  ? 517 ILE B CG1 1 
ATOM   7413 C  CG2 . ILE B 1 517 ? 141.597 120.835 158.788 1.00 31.12  ? 517 ILE B CG2 1 
ATOM   7414 C  CD1 . ILE B 1 517 ? 143.373 119.080 157.140 1.00 31.12  ? 517 ILE B CD1 1 
ATOM   7415 N  N   . PRO B 1 518 ? 141.911 124.229 157.904 1.00 31.02  ? 518 PRO B N   1 
ATOM   7416 C  CA  . PRO B 1 518 ? 140.780 125.173 157.878 1.00 31.02  ? 518 PRO B CA  1 
ATOM   7417 C  C   . PRO B 1 518 ? 140.537 125.776 156.508 1.00 31.02  ? 518 PRO B C   1 
ATOM   7418 O  O   . PRO B 1 518 ? 139.381 125.983 156.124 1.00 31.02  ? 518 PRO B O   1 
ATOM   7419 C  CB  . PRO B 1 518 ? 141.186 126.244 158.901 1.00 31.02  ? 518 PRO B CB  1 
ATOM   7420 C  CG  . PRO B 1 518 ? 142.250 125.630 159.716 1.00 31.02  ? 518 PRO B CG  1 
ATOM   7421 C  CD  . PRO B 1 518 ? 142.969 124.687 158.820 1.00 31.02  ? 518 PRO B CD  1 
ATOM   7422 N  N   . SER B 1 519 ? 141.600 126.050 155.752 1.00 29.54  ? 519 SER B N   1 
ATOM   7423 C  CA  . SER B 1 519 ? 141.437 126.673 154.444 1.00 29.54  ? 519 SER B CA  1 
ATOM   7424 C  C   . SER B 1 519 ? 140.732 125.738 153.470 1.00 29.54  ? 519 SER B C   1 
ATOM   7425 O  O   . SER B 1 519 ? 139.804 126.148 152.763 1.00 29.54  ? 519 SER B O   1 
ATOM   7426 C  CB  . SER B 1 519 ? 142.799 127.100 153.901 1.00 29.54  ? 519 SER B CB  1 
ATOM   7427 O  OG  . SER B 1 519 ? 143.455 127.961 154.814 1.00 29.54  ? 519 SER B OG  1 
ATOM   7428 N  N   . THR B 1 520 ? 141.155 124.472 153.419 1.00 28.48  ? 520 THR B N   1 
ATOM   7429 C  CA  . THR B 1 520 ? 140.509 123.534 152.509 1.00 28.48  ? 520 THR B CA  1 
ATOM   7430 C  C   . THR B 1 520 ? 139.108 123.170 152.980 1.00 28.48  ? 520 THR B C   1 
ATOM   7431 O  O   . THR B 1 520 ? 138.255 122.819 152.158 1.00 28.48  ? 520 THR B O   1 
ATOM   7432 C  CB  . THR B 1 520 ? 141.355 122.271 152.337 1.00 28.48  ? 520 THR B CB  1 
ATOM   7433 O  OG1 . THR B 1 520 ? 140.711 121.393 151.407 1.00 28.48  ? 520 THR B OG1 1 
ATOM   7434 C  CG2 . THR B 1 520 ? 141.524 121.547 153.656 1.00 28.48  ? 520 THR B CG2 1 
ATOM   7435 N  N   . LEU B 1 521 ? 138.847 123.241 154.288 1.00 26.12  ? 521 LEU B N   1 
ATOM   7436 C  CA  . LEU B 1 521 ? 137.489 123.004 154.765 1.00 26.12  ? 521 LEU B CA  1 
ATOM   7437 C  C   . LEU B 1 521 ? 136.566 124.159 154.400 1.00 26.12  ? 521 LEU B C   1 
ATOM   7438 O  O   . LEU B 1 521 ? 135.417 123.938 154.000 1.00 26.12  ? 521 LEU B O   1 
ATOM   7439 C  CB  . LEU B 1 521 ? 137.490 122.774 156.275 1.00 26.12  ? 521 LEU B CB  1 
ATOM   7440 C  CG  . LEU B 1 521 ? 137.781 121.347 156.742 1.00 26.12  ? 521 LEU B CG  1 
ATOM   7441 C  CD1 . LEU B 1 521 ? 137.366 121.168 158.191 1.00 26.12  ? 521 LEU B CD1 1 
ATOM   7442 C  CD2 . LEU B 1 521 ? 137.080 120.337 155.853 1.00 26.12  ? 521 LEU B CD2 1 
ATOM   7443 N  N   . CYS B 1 522 ? 137.049 125.395 154.524 1.00 29.60  ? 522 CYS B N   1 
ATOM   7444 C  CA  . CYS B 1 522 ? 136.234 126.572 154.258 1.00 29.60  ? 522 CYS B CA  1 
ATOM   7445 C  C   . CYS B 1 522 ? 136.167 126.934 152.781 1.00 29.60  ? 522 CYS B C   1 
ATOM   7446 O  O   . CYS B 1 522 ? 135.342 127.774 152.408 1.00 29.60  ? 522 CYS B O   1 
ATOM   7447 C  CB  . CYS B 1 522 ? 136.769 127.763 155.053 1.00 29.60  ? 522 CYS B CB  1 
ATOM   7448 S  SG  . CYS B 1 522 ? 136.404 127.696 156.819 1.00 29.60  ? 522 CYS B SG  1 
ATOM   7449 N  N   . THR B 1 523 ? 137.015 126.339 151.940 1.00 27.71  ? 523 THR B N   1 
ATOM   7450 C  CA  . THR B 1 523 ? 136.927 126.594 150.506 1.00 27.71  ? 523 THR B CA  1 
ATOM   7451 C  C   . THR B 1 523 ? 135.596 126.116 149.944 1.00 27.71  ? 523 THR B C   1 
ATOM   7452 O  O   . THR B 1 523 ? 134.986 126.793 149.108 1.00 27.71  ? 523 THR B O   1 
ATOM   7453 C  CB  . THR B 1 523 ? 138.082 125.911 149.775 1.00 27.71  ? 523 THR B CB  1 
ATOM   7454 O  OG1 . THR B 1 523 ? 139.305 126.148 150.481 1.00 27.71  ? 523 THR B OG1 1 
ATOM   7455 C  CG2 . THR B 1 523 ? 138.208 126.449 148.363 1.00 27.71  ? 523 THR B CG2 1 
ATOM   7456 N  N   . SER B 1 524 ? 135.128 124.952 150.393 1.00 26.97  ? 524 SER B N   1 
ATOM   7457 C  CA  . SER B 1 524 ? 133.882 124.384 149.895 1.00 26.97  ? 524 SER B CA  1 
ATOM   7458 C  C   . SER B 1 524 ? 132.647 125.085 150.443 1.00 26.97  ? 524 SER B C   1 
ATOM   7459 O  O   . SER B 1 524 ? 131.540 124.797 149.978 1.00 26.97  ? 524 SER B O   1 
ATOM   7460 C  CB  . SER B 1 524 ? 133.821 122.895 150.229 1.00 26.97  ? 524 SER B CB  1 
ATOM   7461 O  OG  . SER B 1 524 ? 133.795 122.694 151.628 1.00 26.97  ? 524 SER B OG  1 
ATOM   7462 N  N   . PHE B 1 525 ? 132.802 125.990 151.410 1.00 25.46  ? 525 PHE B N   1 
ATOM   7463 C  CA  . PHE B 1 525 ? 131.666 126.716 151.980 1.00 25.46  ? 525 PHE B CA  1 
ATOM   7464 C  C   . PHE B 1 525 ? 131.279 127.866 151.050 1.00 25.46  ? 525 PHE B C   1 
ATOM   7465 O  O   . PHE B 1 525 ? 131.331 129.048 151.397 1.00 25.46  ? 525 PHE B O   1 
ATOM   7466 C  CB  . PHE B 1 525 ? 131.995 127.218 153.378 1.00 25.46  ? 525 PHE B CB  1 
ATOM   7467 C  CG  . PHE B 1 525 ? 132.155 126.125 154.390 1.00 25.46  ? 525 PHE B CG  1 
ATOM   7468 C  CD1 . PHE B 1 525 ? 131.574 124.887 154.190 1.00 25.46  ? 525 PHE B CD1 1 
ATOM   7469 C  CD2 . PHE B 1 525 ? 132.885 126.335 155.544 1.00 25.46  ? 525 PHE B CD2 1 
ATOM   7470 C  CE1 . PHE B 1 525 ? 131.722 123.881 155.118 1.00 25.46  ? 525 PHE B CE1 1 
ATOM   7471 C  CE2 . PHE B 1 525 ? 133.035 125.332 156.476 1.00 25.46  ? 525 PHE B CE2 1 
ATOM   7472 C  CZ  . PHE B 1 525 ? 132.454 124.103 156.262 1.00 25.46  ? 525 PHE B CZ  1 
ATOM   7473 N  N   . ALA B 1 526 ? 130.882 127.494 149.837 1.00 27.34  ? 526 ALA B N   1 
ATOM   7474 C  CA  . ALA B 1 526 ? 130.376 128.436 148.846 1.00 27.34  ? 526 ALA B CA  1 
ATOM   7475 C  C   . ALA B 1 526 ? 128.856 128.311 148.834 1.00 27.34  ? 526 ALA B C   1 
ATOM   7476 O  O   . ALA B 1 526 ? 128.270 127.649 147.979 1.00 27.34  ? 526 ALA B O   1 
ATOM   7477 C  CB  . ALA B 1 526 ? 130.979 128.163 147.472 1.00 27.34  ? 526 ALA B CB  1 
ATOM   7478 N  N   . PHE B 1 527 ? 128.215 128.962 149.802 1.00 24.28  ? 527 PHE B N   1 
ATOM   7479 C  CA  . PHE B 1 527 ? 126.768 128.925 149.937 1.00 24.28  ? 527 PHE B CA  1 
ATOM   7480 C  C   . PHE B 1 527 ? 126.096 130.203 149.465 1.00 24.28  ? 527 PHE B C   1 
ATOM   7481 O  O   . PHE B 1 527 ? 124.866 130.299 149.524 1.00 24.28  ? 527 PHE B O   1 
ATOM   7482 C  CB  . PHE B 1 527 ? 126.377 128.653 151.394 1.00 24.28  ? 527 PHE B CB  1 
ATOM   7483 C  CG  . PHE B 1 527 ? 127.022 127.433 151.979 1.00 24.28  ? 527 PHE B CG  1 
ATOM   7484 C  CD1 . PHE B 1 527 ? 126.753 126.179 151.463 1.00 24.28  ? 527 PHE B CD1 1 
ATOM   7485 C  CD2 . PHE B 1 527 ? 127.880 127.537 153.055 1.00 24.28  ? 527 PHE B CD2 1 
ATOM   7486 C  CE1 . PHE B 1 527 ? 127.338 125.055 152.003 1.00 24.28  ? 527 PHE B CE1 1 
ATOM   7487 C  CE2 . PHE B 1 527 ? 128.466 126.415 153.600 1.00 24.28  ? 527 PHE B CE2 1 
ATOM   7488 C  CZ  . PHE B 1 527 ? 128.195 125.172 153.073 1.00 24.28  ? 527 PHE B CZ  1 
ATOM   7489 N  N   . LEU B 1 528 ? 126.861 131.179 148.993 1.00 26.32  ? 528 LEU B N   1 
ATOM   7490 C  CA  . LEU B 1 528 ? 126.325 132.463 148.567 1.00 26.32  ? 528 LEU B CA  1 
ATOM   7491 C  C   . LEU B 1 528 ? 126.318 132.506 147.044 1.00 26.32  ? 528 LEU B C   1 
ATOM   7492 O  O   . LEU B 1 528 ? 127.332 132.194 146.409 1.00 26.32  ? 528 LEU B O   1 
ATOM   7493 C  CB  . LEU B 1 528 ? 127.163 133.615 149.122 1.00 26.32  ? 528 LEU B CB  1 
ATOM   7494 C  CG  . LEU B 1 528 ? 127.027 134.104 150.566 1.00 26.32  ? 528 LEU B CG  1 
ATOM   7495 C  CD1 . LEU B 1 528 ? 125.641 134.634 150.840 1.00 26.32  ? 528 LEU B CD1 1 
ATOM   7496 C  CD2 . LEU B 1 528 ? 127.405 133.022 151.563 1.00 26.32  ? 528 LEU B CD2 1 
ATOM   7497 N  N   . LEU B 1 529 ? 125.171 132.871 146.466 1.00 25.37  ? 529 LEU B N   1 
ATOM   7498 C  CA  . LEU B 1 529 ? 124.964 132.986 145.024 1.00 25.37  ? 529 LEU B CA  1 
ATOM   7499 C  C   . LEU B 1 529 ? 125.106 131.651 144.301 1.00 25.37  ? 529 LEU B C   1 
ATOM   7500 O  O   . LEU B 1 529 ? 125.725 130.713 144.818 1.00 25.37  ? 529 LEU B O   1 
ATOM   7501 C  CB  . LEU B 1 529 ? 125.939 133.992 144.402 1.00 25.37  ? 529 LEU B CB  1 
ATOM   7502 C  CG  . LEU B 1 529 ? 126.150 135.371 145.022 1.00 25.37  ? 529 LEU B CG  1 
ATOM   7503 C  CD1 . LEU B 1 529 ? 127.249 136.100 144.270 1.00 25.37  ? 529 LEU B CD1 1 
ATOM   7504 C  CD2 . LEU B 1 529 ? 124.868 136.172 144.998 1.00 25.37  ? 529 LEU B CD2 1 
ATOM   7505 N  N   . PRO B 1 530 ? 124.547 131.531 143.099 1.00 23.44  ? 530 PRO B N   1 
ATOM   7506 C  CA  . PRO B 1 530 ? 124.886 130.398 142.229 1.00 23.44  ? 530 PRO B CA  1 
ATOM   7507 C  C   . PRO B 1 530 ? 126.284 130.547 141.653 1.00 23.44  ? 530 PRO B C   1 
ATOM   7508 O  O   . PRO B 1 530 ? 127.077 131.342 142.164 1.00 23.44  ? 530 PRO B O   1 
ATOM   7509 C  CB  . PRO B 1 530 ? 123.810 130.452 141.139 1.00 23.44  ? 530 PRO B CB  1 
ATOM   7510 C  CG  . PRO B 1 530 ? 123.346 131.860 141.138 1.00 23.44  ? 530 PRO B CG  1 
ATOM   7511 C  CD  . PRO B 1 530 ? 123.436 132.329 142.555 1.00 23.44  ? 530 PRO B CD  1 
ATOM   7512 N  N   . VAL B 1 531 ? 126.621 129.712 140.664 1.00 24.37  ? 531 VAL B N   1 
ATOM   7513 C  CA  . VAL B 1 531 ? 127.850 129.719 139.858 1.00 24.37  ? 531 VAL B CA  1 
ATOM   7514 C  C   . VAL B 1 531 ? 129.101 129.571 140.723 1.00 24.37  ? 531 VAL B C   1 
ATOM   7515 O  O   . VAL B 1 531 ? 130.124 129.052 140.261 1.00 24.37  ? 531 VAL B O   1 
ATOM   7516 C  CB  . VAL B 1 531 ? 127.962 130.958 138.932 1.00 24.37  ? 531 VAL B CB  1 
ATOM   7517 C  CG1 . VAL B 1 531 ? 128.126 132.284 139.672 1.00 24.37  ? 531 VAL B CG1 1 
ATOM   7518 C  CG2 . VAL B 1 531 ? 129.080 130.771 137.921 1.00 24.37  ? 531 VAL B CG2 1 
ATOM   7519 N  N   . ALA B 1 532 ? 129.038 130.014 141.980 1.00 29.60  ? 532 ALA B N   1 
ATOM   7520 C  CA  . ALA B 1 532 ? 130.137 129.759 142.904 1.00 29.60  ? 532 ALA B CA  1 
ATOM   7521 C  C   . ALA B 1 532 ? 130.349 128.265 143.099 1.00 29.60  ? 532 ALA B C   1 
ATOM   7522 O  O   . ALA B 1 532 ? 131.490 127.789 143.142 1.00 29.60  ? 532 ALA B O   1 
ATOM   7523 C  CB  . ALA B 1 532 ? 129.863 130.439 144.244 1.00 29.60  ? 532 ALA B CB  1 
ATOM   7524 N  N   . ASN B 1 533 ? 129.260 127.509 143.219 1.00 27.25  ? 533 ASN B N   1 
ATOM   7525 C  CA  . ASN B 1 533 ? 129.302 126.067 143.383 1.00 27.25  ? 533 ASN B CA  1 
ATOM   7526 C  C   . ASN B 1 533 ? 128.315 125.465 142.390 1.00 27.25  ? 533 ASN B C   1 
ATOM   7527 O  O   . ASN B 1 533 ? 127.173 125.946 142.290 1.00 27.25  ? 533 ASN B O   1 
ATOM   7528 C  CB  . ASN B 1 533 ? 128.944 125.678 144.825 1.00 27.25  ? 533 ASN B CB  1 
ATOM   7529 C  CG  . ASN B 1 533 ? 129.570 124.367 145.258 1.00 27.25  ? 533 ASN B CG  1 
ATOM   7530 O  OD1 . ASN B 1 533 ? 130.320 123.743 144.511 1.00 27.25  ? 533 ASN B OD1 1 
ATOM   7531 N  ND2 . ASN B 1 533 ? 129.269 123.947 146.480 1.00 27.25  ? 533 ASN B ND2 1 
ATOM   7532 N  N   . PRO B 1 534 ? 128.710 124.451 141.625 1.00 24.06  ? 534 PRO B N   1 
ATOM   7533 C  CA  . PRO B 1 534 ? 127.797 123.853 140.637 1.00 24.06  ? 534 PRO B CA  1 
ATOM   7534 C  C   . PRO B 1 534 ? 126.502 123.346 141.254 1.00 24.06  ? 534 PRO B C   1 
ATOM   7535 O  O   . PRO B 1 534 ? 125.446 123.451 140.611 1.00 24.06  ? 534 PRO B O   1 
ATOM   7536 C  CB  . PRO B 1 534 ? 128.627 122.706 140.046 1.00 24.06  ? 534 PRO B CB  1 
ATOM   7537 C  CG  . PRO B 1 534 ? 130.025 123.183 140.160 1.00 24.06  ? 534 PRO B CG  1 
ATOM   7538 C  CD  . PRO B 1 534 ? 130.099 124.002 141.426 1.00 24.06  ? 534 PRO B CD  1 
ATOM   7539 N  N   . PRO B 1 535 ? 126.515 122.767 142.470 1.00 23.50  ? 535 PRO B N   1 
ATOM   7540 C  CA  . PRO B 1 535 ? 125.222 122.417 143.086 1.00 23.50  ? 535 PRO B CA  1 
ATOM   7541 C  C   . PRO B 1 535 ? 124.291 123.604 143.228 1.00 23.50  ? 535 PRO B C   1 
ATOM   7542 O  O   . PRO B 1 535 ? 123.076 123.473 143.020 1.00 23.50  ? 535 PRO B O   1 
ATOM   7543 C  CB  . PRO B 1 535 ? 125.629 121.854 144.453 1.00 23.50  ? 535 PRO B CB  1 
ATOM   7544 C  CG  . PRO B 1 535 ? 126.955 121.299 144.233 1.00 23.50  ? 535 PRO B CG  1 
ATOM   7545 C  CD  . PRO B 1 535 ? 127.633 122.209 143.256 1.00 23.50  ? 535 PRO B CD  1 
ATOM   7546 N  N   . ASN B 1 536 ? 124.840 124.771 143.566 1.00 24.79  ? 536 ASN B N   1 
ATOM   7547 C  CA  . ASN B 1 536 ? 124.021 125.969 143.691 1.00 24.79  ? 536 ASN B CA  1 
ATOM   7548 C  C   . ASN B 1 536 ? 123.342 126.309 142.373 1.00 24.79  ? 536 ASN B C   1 
ATOM   7549 O  O   . ASN B 1 536 ? 122.146 126.611 142.345 1.00 24.79  ? 536 ASN B O   1 
ATOM   7550 C  CB  . ASN B 1 536 ? 124.881 127.139 144.165 1.00 24.79  ? 536 ASN B CB  1 
ATOM   7551 C  CG  . ASN B 1 536 ? 125.485 126.902 145.533 1.00 24.79  ? 536 ASN B CG  1 
ATOM   7552 O  OD1 . ASN B 1 536 ? 125.003 126.075 146.303 1.00 24.79  ? 536 ASN B OD1 1 
ATOM   7553 N  ND2 . ASN B 1 536 ? 126.541 127.639 145.847 1.00 24.79  ? 536 ASN B ND2 1 
ATOM   7554 N  N   . ALA B 1 537 ? 124.085 126.249 141.267 1.00 24.17  ? 537 ALA B N   1 
ATOM   7555 C  CA  . ALA B 1 537 ? 123.504 126.559 139.964 1.00 24.17  ? 537 ALA B CA  1 
ATOM   7556 C  C   . ALA B 1 537 ? 122.472 125.517 139.550 1.00 24.17  ? 537 ALA B C   1 
ATOM   7557 O  O   . ALA B 1 537 ? 121.412 125.861 139.009 1.00 24.17  ? 537 ALA B O   1 
ATOM   7558 C  CB  . ALA B 1 537 ? 124.608 126.669 138.917 1.00 24.17  ? 537 ALA B CB  1 
ATOM   7559 N  N   . ILE B 1 538 ? 122.763 124.237 139.792 1.00 23.99  ? 538 ILE B N   1 
ATOM   7560 C  CA  . ILE B 1 538 ? 121.823 123.182 139.421 1.00 23.99  ? 538 ILE B CA  1 
ATOM   7561 C  C   . ILE B 1 538 ? 120.509 123.357 140.165 1.00 23.99  ? 538 ILE B C   1 
ATOM   7562 O  O   . ILE B 1 538 ? 119.425 123.223 139.585 1.00 23.99  ? 538 ILE B O   1 
ATOM   7563 C  CB  . ILE B 1 538 ? 122.443 121.799 139.680 1.00 23.99  ? 538 ILE B CB  1 
ATOM   7564 C  CG1 . ILE B 1 538 ? 123.568 121.537 138.683 1.00 23.99  ? 538 ILE B CG1 1 
ATOM   7565 C  CG2 . ILE B 1 538 ? 121.383 120.716 139.601 1.00 23.99  ? 538 ILE B CG2 1 
ATOM   7566 C  CD1 . ILE B 1 538 ? 124.115 120.143 138.746 1.00 23.99  ? 538 ILE B CD1 1 
ATOM   7567 N  N   . VAL B 1 539 ? 120.581 123.666 141.458 1.00 25.42  ? 539 VAL B N   1 
ATOM   7568 C  CA  . VAL B 1 539 ? 119.368 123.925 142.223 1.00 25.42  ? 539 VAL B CA  1 
ATOM   7569 C  C   . VAL B 1 539 ? 118.685 125.204 141.747 1.00 25.42  ? 539 VAL B C   1 
ATOM   7570 O  O   . VAL B 1 539 ? 117.453 125.273 141.667 1.00 25.42  ? 539 VAL B O   1 
ATOM   7571 C  CB  . VAL B 1 539 ? 119.703 123.972 143.721 1.00 25.42  ? 539 VAL B CB  1 
ATOM   7572 C  CG1 . VAL B 1 539 ? 118.512 124.425 144.492 1.00 25.42  ? 539 VAL B CG1 1 
ATOM   7573 C  CG2 . VAL B 1 539 ? 120.131 122.595 144.189 1.00 25.42  ? 539 VAL B CG2 1 
ATOM   7574 N  N   . PHE B 1 540 ? 119.471 126.230 141.416 1.00 28.70  ? 540 PHE B N   1 
ATOM   7575 C  CA  . PHE B 1 540 ? 118.917 127.482 140.913 1.00 28.70  ? 540 PHE B CA  1 
ATOM   7576 C  C   . PHE B 1 540 ? 118.164 127.277 139.607 1.00 28.70  ? 540 PHE B C   1 
ATOM   7577 O  O   . PHE B 1 540 ? 117.288 128.078 139.260 1.00 28.70  ? 540 PHE B O   1 
ATOM   7578 C  CB  . PHE B 1 540 ? 120.050 128.488 140.719 1.00 28.70  ? 540 PHE B CB  1 
ATOM   7579 C  CG  . PHE B 1 540 ? 119.648 129.912 140.936 1.00 28.70  ? 540 PHE B CG  1 
ATOM   7580 C  CD1 . PHE B 1 540 ? 119.187 130.682 139.885 1.00 28.70  ? 540 PHE B CD1 1 
ATOM   7581 C  CD2 . PHE B 1 540 ? 119.746 130.486 142.190 1.00 28.70  ? 540 PHE B CD2 1 
ATOM   7582 C  CE1 . PHE B 1 540 ? 118.826 131.996 140.082 1.00 28.70  ? 540 PHE B CE1 1 
ATOM   7583 C  CE2 . PHE B 1 540 ? 119.383 131.799 142.393 1.00 28.70  ? 540 PHE B CE2 1 
ATOM   7584 C  CZ  . PHE B 1 540 ? 118.923 132.555 141.338 1.00 28.70  ? 540 PHE B CZ  1 
ATOM   7585 N  N   . SER B 1 541 ? 118.495 126.214 138.873 1.00 27.69  ? 541 SER B N   1 
ATOM   7586 C  CA  . SER B 1 541 ? 117.871 125.964 137.579 1.00 27.69  ? 541 SER B CA  1 
ATOM   7587 C  C   . SER B 1 541 ? 116.370 125.717 137.673 1.00 27.69  ? 541 SER B C   1 
ATOM   7588 O  O   . SER B 1 541 ? 115.682 125.787 136.649 1.00 27.69  ? 541 SER B O   1 
ATOM   7589 C  CB  . SER B 1 541 ? 118.532 124.762 136.905 1.00 27.69  ? 541 SER B CB  1 
ATOM   7590 O  OG  . SER B 1 541 ? 117.939 123.550 137.334 1.00 27.69  ? 541 SER B OG  1 
ATOM   7591 N  N   . TYR B 1 542 ? 115.844 125.430 138.865 1.00 32.61  ? 542 TYR B N   1 
ATOM   7592 C  CA  . TYR B 1 542 ? 114.465 124.978 139.017 1.00 32.61  ? 542 TYR B CA  1 
ATOM   7593 C  C   . TYR B 1 542 ? 113.478 126.114 139.265 1.00 32.61  ? 542 TYR B C   1 
ATOM   7594 O  O   . TYR B 1 542 ? 112.429 125.891 139.882 1.00 32.61  ? 542 TYR B O   1 
ATOM   7595 C  CB  . TYR B 1 542 ? 114.383 123.932 140.127 1.00 32.61  ? 542 TYR B CB  1 
ATOM   7596 C  CG  . TYR B 1 542 ? 114.708 122.546 139.627 1.00 32.61  ? 542 TYR B CG  1 
ATOM   7597 C  CD1 . TYR B 1 542 ? 113.752 121.787 138.968 1.00 32.61  ? 542 TYR B CD1 1 
ATOM   7598 C  CD2 . TYR B 1 542 ? 115.967 121.997 139.810 1.00 32.61  ? 542 TYR B CD2 1 
ATOM   7599 C  CE1 . TYR B 1 542 ? 114.042 120.522 138.504 1.00 32.61  ? 542 TYR B CE1 1 
ATOM   7600 C  CE2 . TYR B 1 542 ? 116.268 120.734 139.341 1.00 32.61  ? 542 TYR B CE2 1 
ATOM   7601 C  CZ  . TYR B 1 542 ? 115.301 120.000 138.695 1.00 32.61  ? 542 TYR B CZ  1 
ATOM   7602 O  OH  . TYR B 1 542 ? 115.595 118.740 138.233 1.00 32.61  ? 542 TYR B OH  1 
ATOM   7603 N  N   . GLY B 1 543 ? 113.781 127.325 138.802 1.00 37.33  ? 543 GLY B N   1 
ATOM   7604 C  CA  . GLY B 1 543 ? 112.798 128.380 138.696 1.00 37.33  ? 543 GLY B CA  1 
ATOM   7605 C  C   . GLY B 1 543 ? 112.677 129.295 139.895 1.00 37.33  ? 543 GLY B C   1 
ATOM   7606 O  O   . GLY B 1 543 ? 112.124 130.392 139.762 1.00 37.33  ? 543 GLY B O   1 
ATOM   7607 N  N   . HIS B 1 544 ? 113.167 128.883 141.064 1.00 39.07  ? 544 HIS B N   1 
ATOM   7608 C  CA  . HIS B 1 544 ? 113.104 129.720 142.262 1.00 39.07  ? 544 HIS B CA  1 
ATOM   7609 C  C   . HIS B 1 544 ? 114.348 130.603 142.280 1.00 39.07  ? 544 HIS B C   1 
ATOM   7610 O  O   . HIS B 1 544 ? 115.304 130.392 143.030 1.00 39.07  ? 544 HIS B O   1 
ATOM   7611 C  CB  . HIS B 1 544 ? 112.975 128.853 143.506 1.00 39.07  ? 544 HIS B CB  1 
ATOM   7612 C  CG  . HIS B 1 544 ? 112.033 127.703 143.331 1.00 39.07  ? 544 HIS B CG  1 
ATOM   7613 N  ND1 . HIS B 1 544 ? 112.437 126.389 143.415 1.00 39.07  ? 544 HIS B ND1 1 
ATOM   7614 C  CD2 . HIS B 1 544 ? 110.708 127.672 143.055 1.00 39.07  ? 544 HIS B CD2 1 
ATOM   7615 C  CE1 . HIS B 1 544 ? 111.400 125.597 143.208 1.00 39.07  ? 544 HIS B CE1 1 
ATOM   7616 N  NE2 . HIS B 1 544 ? 110.339 126.351 142.987 1.00 39.07  ? 544 HIS B NE2 1 
ATOM   7617 N  N   . LEU B 1 545 ? 114.311 131.632 141.432 1.00 42.76  ? 545 LEU B N   1 
ATOM   7618 C  CA  . LEU B 1 545 ? 115.485 132.403 141.050 1.00 42.76  ? 545 LEU B CA  1 
ATOM   7619 C  C   . LEU B 1 545 ? 115.713 133.634 141.923 1.00 42.76  ? 545 LEU B C   1 
ATOM   7620 O  O   . LEU B 1 545 ? 116.406 134.564 141.498 1.00 42.76  ? 545 LEU B O   1 
ATOM   7621 C  CB  . LEU B 1 545 ? 115.381 132.801 139.574 1.00 42.76  ? 545 LEU B CB  1 
ATOM   7622 C  CG  . LEU B 1 545 ? 114.130 133.549 139.094 1.00 42.76  ? 545 LEU B CG  1 
ATOM   7623 C  CD1 . LEU B 1 545 ? 114.263 135.063 139.230 1.00 42.76  ? 545 LEU B CD1 1 
ATOM   7624 C  CD2 . LEU B 1 545 ? 113.800 133.165 137.658 1.00 42.76  ? 545 LEU B CD2 1 
ATOM   7625 N  N   . LYS B 1 546 ? 115.163 133.658 143.134 1.00 35.10  ? 546 LYS B N   1 
ATOM   7626 C  CA  . LYS B 1 546 ? 115.366 134.790 144.030 1.00 35.10  ? 546 LYS B CA  1 
ATOM   7627 C  C   . LYS B 1 546 ? 116.754 134.685 144.649 1.00 35.10  ? 546 LYS B C   1 
ATOM   7628 O  O   . LYS B 1 546 ? 116.988 133.854 145.532 1.00 35.10  ? 546 LYS B O   1 
ATOM   7629 C  CB  . LYS B 1 546 ? 114.280 134.830 145.100 1.00 35.10  ? 546 LYS B CB  1 
ATOM   7630 C  CG  . LYS B 1 546 ? 113.909 136.236 145.551 1.00 35.10  ? 546 LYS B CG  1 
ATOM   7631 C  CD  . LYS B 1 546 ? 113.618 137.146 144.367 1.00 35.10  ? 546 LYS B CD  1 
ATOM   7632 C  CE  . LYS B 1 546 ? 112.371 136.708 143.616 1.00 35.10  ? 546 LYS B CE  1 
ATOM   7633 N  NZ  . LYS B 1 546 ? 112.139 137.533 142.400 1.00 35.10  ? 546 LYS B NZ  1 
ATOM   7634 N  N   . VAL B 1 547 ? 117.678 135.524 144.178 1.00 30.34  ? 547 VAL B N   1 
ATOM   7635 C  CA  . VAL B 1 547 ? 119.050 135.485 144.675 1.00 30.34  ? 547 VAL B CA  1 
ATOM   7636 C  C   . VAL B 1 547 ? 119.115 135.954 146.123 1.00 30.34  ? 547 VAL B C   1 
ATOM   7637 O  O   . VAL B 1 547 ? 119.924 135.454 146.912 1.00 30.34  ? 547 VAL B O   1 
ATOM   7638 C  CB  . VAL B 1 547 ? 119.970 136.319 143.763 1.00 30.34  ? 547 VAL B CB  1 
ATOM   7639 C  CG1 . VAL B 1 547 ? 121.317 136.546 144.416 1.00 30.34  ? 547 VAL B CG1 1 
ATOM   7640 C  CG2 . VAL B 1 547 ? 120.158 135.621 142.433 1.00 30.34  ? 547 VAL B CG2 1 
ATOM   7641 N  N   . ILE B 1 548 ? 118.272 136.919 146.498 1.00 31.89  ? 548 ILE B N   1 
ATOM   7642 C  CA  . ILE B 1 548 ? 118.375 137.515 147.828 1.00 31.89  ? 548 ILE B CA  1 
ATOM   7643 C  C   . ILE B 1 548 ? 118.063 136.490 148.915 1.00 31.89  ? 548 ILE B C   1 
ATOM   7644 O  O   . ILE B 1 548 ? 118.692 136.492 149.980 1.00 31.89  ? 548 ILE B O   1 
ATOM   7645 C  CB  . ILE B 1 548 ? 117.479 138.765 147.927 1.00 31.89  ? 548 ILE B CB  1 
ATOM   7646 C  CG1 . ILE B 1 548 ? 117.902 139.626 149.119 1.00 31.89  ? 548 ILE B CG1 1 
ATOM   7647 C  CG2 . ILE B 1 548 ? 116.000 138.399 147.992 1.00 31.89  ? 548 ILE B CG2 1 
ATOM   7648 C  CD1 . ILE B 1 548 ? 119.366 140.000 149.109 1.00 31.89  ? 548 ILE B CD1 1 
ATOM   7649 N  N   . ASP B 1 549 ? 117.104 135.593 148.669 1.00 32.22  ? 549 ASP B N   1 
ATOM   7650 C  CA  . ASP B 1 549 ? 116.829 134.529 149.631 1.00 32.22  ? 549 ASP B CA  1 
ATOM   7651 C  C   . ASP B 1 549 ? 118.032 133.609 149.780 1.00 32.22  ? 549 ASP B C   1 
ATOM   7652 O  O   . ASP B 1 549 ? 118.392 133.208 150.897 1.00 32.22  ? 549 ASP B O   1 
ATOM   7653 C  CB  . ASP B 1 549 ? 115.601 133.731 149.196 1.00 32.22  ? 549 ASP B CB  1 
ATOM   7654 C  CG  . ASP B 1 549 ? 114.395 134.610 148.942 1.00 32.22  ? 549 ASP B CG  1 
ATOM   7655 O  OD1 . ASP B 1 549 ? 114.344 135.729 149.493 1.00 32.22  ? 549 ASP B OD1 1 
ATOM   7656 O  OD2 . ASP B 1 549 ? 113.497 134.181 148.190 1.00 32.22  ? 549 ASP B OD2 1 
ATOM   7657 N  N   . MET B 1 550 ? 118.666 133.268 148.659 1.00 26.71  ? 550 MET B N   1 
ATOM   7658 C  CA  . MET B 1 550 ? 119.840 132.409 148.701 1.00 26.71  ? 550 MET B CA  1 
ATOM   7659 C  C   . MET B 1 550 ? 120.975 133.071 149.467 1.00 26.71  ? 550 MET B C   1 
ATOM   7660 O  O   . MET B 1 550 ? 121.674 132.413 150.240 1.00 26.71  ? 550 MET B O   1 
ATOM   7661 C  CB  . MET B 1 550 ? 120.276 132.058 147.282 1.00 26.71  ? 550 MET B CB  1 
ATOM   7662 C  CG  . MET B 1 550 ? 121.464 131.136 147.228 1.00 26.71  ? 550 MET B CG  1 
ATOM   7663 S  SD  . MET B 1 550 ? 121.436 130.089 145.769 1.00 26.71  ? 550 MET B SD  1 
ATOM   7664 C  CE  . MET B 1 550 ? 122.754 128.964 146.185 1.00 26.71  ? 550 MET B CE  1 
ATOM   7665 N  N   . VAL B 1 551 ? 121.166 134.376 149.271 1.00 25.49  ? 551 VAL B N   1 
ATOM   7666 C  CA  . VAL B 1 551 ? 122.200 135.103 150.003 1.00 25.49  ? 551 VAL B CA  1 
ATOM   7667 C  C   . VAL B 1 551 ? 121.884 135.128 151.493 1.00 25.49  ? 551 VAL B C   1 
ATOM   7668 O  O   . VAL B 1 551 ? 122.771 134.933 152.336 1.00 25.49  ? 551 VAL B O   1 
ATOM   7669 C  CB  . VAL B 1 551 ? 122.357 136.525 149.435 1.00 25.49  ? 551 VAL B CB  1 
ATOM   7670 C  CG1 . VAL B 1 551 ? 123.280 137.351 150.313 1.00 25.49  ? 551 VAL B CG1 1 
ATOM   7671 C  CG2 . VAL B 1 551 ? 122.880 136.471 148.015 1.00 25.49  ? 551 VAL B CG2 1 
ATOM   7672 N  N   . LYS B 1 552 ? 120.618 135.371 151.843 1.00 26.45  ? 552 LYS B N   1 
ATOM   7673 C  CA  . LYS B 1 552 ? 120.236 135.427 153.250 1.00 26.45  ? 552 LYS B CA  1 
ATOM   7674 C  C   . LYS B 1 552 ? 120.490 134.097 153.944 1.00 26.45  ? 552 LYS B C   1 
ATOM   7675 O  O   . LYS B 1 552 ? 120.988 134.065 155.075 1.00 26.45  ? 552 LYS B O   1 
ATOM   7676 C  CB  . LYS B 1 552 ? 118.768 135.828 153.382 1.00 26.45  ? 552 LYS B CB  1 
ATOM   7677 C  CG  . LYS B 1 552 ? 118.505 137.305 153.145 1.00 26.45  ? 552 LYS B CG  1 
ATOM   7678 C  CD  . LYS B 1 552 ? 117.042 137.571 152.824 1.00 26.45  ? 552 LYS B CD  1 
ATOM   7679 C  CE  . LYS B 1 552 ? 116.117 136.754 153.711 1.00 26.45  ? 552 LYS B CE  1 
ATOM   7680 N  NZ  . LYS B 1 552 ? 114.698 136.847 153.271 1.00 26.45  ? 552 LYS B NZ  1 
ATOM   7681 N  N   . ALA B 1 553 ? 120.151 132.987 153.287 1.00 24.88  ? 553 ALA B N   1 
ATOM   7682 C  CA  . ALA B 1 553 ? 120.416 131.682 153.890 1.00 24.88  ? 553 ALA B CA  1 
ATOM   7683 C  C   . ALA B 1 553 ? 121.908 131.368 153.910 1.00 24.88  ? 553 ALA B C   1 
ATOM   7684 O  O   . ALA B 1 553 ? 122.427 130.832 154.901 1.00 24.88  ? 553 ALA B O   1 
ATOM   7685 C  CB  . ALA B 1 553 ? 119.649 130.594 153.144 1.00 24.88  ? 553 ALA B CB  1 
ATOM   7686 N  N   . GLY B 1 554 ? 122.613 131.697 152.824 1.00 25.26  ? 554 GLY B N   1 
ATOM   7687 C  CA  . GLY B 1 554 ? 124.017 131.360 152.717 1.00 25.26  ? 554 GLY B CA  1 
ATOM   7688 C  C   . GLY B 1 554 ? 124.892 132.089 153.708 1.00 25.26  ? 554 GLY B C   1 
ATOM   7689 O  O   . GLY B 1 554 ? 125.883 131.533 154.175 1.00 25.26  ? 554 GLY B O   1 
ATOM   7690 N  N   . LEU B 1 555 ? 124.557 133.339 154.033 1.00 25.13  ? 555 LEU B N   1 
ATOM   7691 C  CA  . LEU B 1 555 ? 125.326 134.054 155.047 1.00 25.13  ? 555 LEU B CA  1 
ATOM   7692 C  C   . LEU B 1 555 ? 125.303 133.305 156.373 1.00 25.13  ? 555 LEU B C   1 
ATOM   7693 O  O   . LEU B 1 555 ? 126.350 133.072 156.989 1.00 25.13  ? 555 LEU B O   1 
ATOM   7694 C  CB  . LEU B 1 555 ? 124.786 135.472 155.219 1.00 25.13  ? 555 LEU B CB  1 
ATOM   7695 C  CG  . LEU B 1 555 ? 125.206 136.478 154.151 1.00 25.13  ? 555 LEU B CG  1 
ATOM   7696 C  CD1 . LEU B 1 555 ? 124.463 137.789 154.331 1.00 25.13  ? 555 LEU B CD1 1 
ATOM   7697 C  CD2 . LEU B 1 555 ? 126.707 136.697 154.209 1.00 25.13  ? 555 LEU B CD2 1 
ATOM   7698 N  N   . GLY B 1 556 ? 124.113 132.900 156.816 1.00 23.92  ? 556 GLY B N   1 
ATOM   7699 C  CA  . GLY B 1 556 ? 124.014 132.165 158.065 1.00 23.92  ? 556 GLY B CA  1 
ATOM   7700 C  C   . GLY B 1 556 ? 124.703 130.816 158.007 1.00 23.92  ? 556 GLY B C   1 
ATOM   7701 O  O   . GLY B 1 556 ? 125.403 130.425 158.946 1.00 23.92  ? 556 GLY B O   1 
ATOM   7702 N  N   . VAL B 1 557 ? 124.520 130.086 156.904 1.00 22.42  ? 557 VAL B N   1 
ATOM   7703 C  CA  . VAL B 1 557 ? 125.139 128.766 156.793 1.00 22.42  ? 557 VAL B CA  1 
ATOM   7704 C  C   . VAL B 1 557 ? 126.660 128.889 156.771 1.00 22.42  ? 557 VAL B C   1 
ATOM   7705 O  O   . VAL B 1 557 ? 127.371 128.083 157.382 1.00 22.42  ? 557 VAL B O   1 
ATOM   7706 C  CB  . VAL B 1 557 ? 124.605 128.022 155.555 1.00 22.42  ? 557 VAL B CB  1 
ATOM   7707 C  CG1 . VAL B 1 557 ? 125.319 126.696 155.384 1.00 22.42  ? 557 VAL B CG1 1 
ATOM   7708 C  CG2 . VAL B 1 557 ? 123.110 127.796 155.686 1.00 22.42  ? 557 VAL B CG2 1 
ATOM   7709 N  N   . ASN B 1 558 ? 127.180 129.903 156.079 1.00 23.02  ? 558 ASN B N   1 
ATOM   7710 C  CA  . ASN B 1 558 ? 128.620 130.125 156.022 1.00 23.02  ? 558 ASN B CA  1 
ATOM   7711 C  C   . ASN B 1 558 ? 129.177 130.524 157.381 1.00 23.02  ? 558 ASN B C   1 
ATOM   7712 O  O   . ASN B 1 558 ? 130.260 130.071 157.769 1.00 23.02  ? 558 ASN B O   1 
ATOM   7713 C  CB  . ASN B 1 558 ? 128.929 131.192 154.973 1.00 23.02  ? 558 ASN B CB  1 
ATOM   7714 C  CG  . ASN B 1 558 ? 130.372 131.176 154.534 1.00 23.02  ? 558 ASN B CG  1 
ATOM   7715 O  OD1 . ASN B 1 558 ? 131.032 130.140 154.571 1.00 23.02  ? 558 ASN B OD1 1 
ATOM   7716 N  ND2 . ASN B 1 558 ? 130.870 132.327 154.100 1.00 23.02  ? 558 ASN B ND2 1 
ATOM   7717 N  N   . ILE B 1 559 ? 128.457 131.374 158.119 1.00 23.19  ? 559 ILE B N   1 
ATOM   7718 C  CA  . ILE B 1 559 ? 128.902 131.740 159.462 1.00 23.19  ? 559 ILE B CA  1 
ATOM   7719 C  C   . ILE B 1 559 ? 128.935 130.512 160.360 1.00 23.19  ? 559 ILE B C   1 
ATOM   7720 O  O   . ILE B 1 559 ? 129.889 130.304 161.122 1.00 23.19  ? 559 ILE B O   1 
ATOM   7721 C  CB  . ILE B 1 559 ? 128.002 132.847 160.043 1.00 23.19  ? 559 ILE B CB  1 
ATOM   7722 C  CG1 . ILE B 1 559 ? 128.267 134.178 159.339 1.00 23.19  ? 559 ILE B CG1 1 
ATOM   7723 C  CG2 . ILE B 1 559 ? 128.221 132.987 161.539 1.00 23.19  ? 559 ILE B CG2 1 
ATOM   7724 C  CD1 . ILE B 1 559 ? 129.734 134.507 159.182 1.00 23.19  ? 559 ILE B CD1 1 
ATOM   7725 N  N   . VAL B 1 560 ? 127.900 129.673 160.277 1.00 23.29  ? 560 VAL B N   1 
ATOM   7726 C  CA  . VAL B 1 560 ? 127.865 128.446 161.068 1.00 23.29  ? 560 VAL B CA  1 
ATOM   7727 C  C   . VAL B 1 560 ? 129.038 127.545 160.709 1.00 23.29  ? 560 VAL B C   1 
ATOM   7728 O  O   . VAL B 1 560 ? 129.708 126.992 161.590 1.00 23.29  ? 560 VAL B O   1 
ATOM   7729 C  CB  . VAL B 1 560 ? 126.518 127.725 160.871 1.00 23.29  ? 560 VAL B CB  1 
ATOM   7730 C  CG1 . VAL B 1 560 ? 126.639 126.260 161.247 1.00 23.29  ? 560 VAL B CG1 1 
ATOM   7731 C  CG2 . VAL B 1 560 ? 125.430 128.402 161.688 1.00 23.29  ? 560 VAL B CG2 1 
ATOM   7732 N  N   . GLY B 1 561 ? 129.305 127.382 159.412 1.00 23.90  ? 561 GLY B N   1 
ATOM   7733 C  CA  . GLY B 1 561 ? 130.404 126.529 158.993 1.00 23.90  ? 561 GLY B CA  1 
ATOM   7734 C  C   . GLY B 1 561 ? 131.752 127.035 159.466 1.00 23.90  ? 561 GLY B C   1 
ATOM   7735 O  O   . GLY B 1 561 ? 132.590 126.256 159.927 1.00 23.90  ? 561 GLY B O   1 
ATOM   7736 N  N   . VAL B 1 562 ? 131.978 128.346 159.366 1.00 24.98  ? 562 VAL B N   1 
ATOM   7737 C  CA  . VAL B 1 562 ? 133.242 128.918 159.823 1.00 24.98  ? 562 VAL B CA  1 
ATOM   7738 C  C   . VAL B 1 562 ? 133.396 128.736 161.327 1.00 24.98  ? 562 VAL B C   1 
ATOM   7739 O  O   . VAL B 1 562 ? 134.475 128.376 161.816 1.00 24.98  ? 562 VAL B O   1 
ATOM   7740 C  CB  . VAL B 1 562 ? 133.338 130.399 159.415 1.00 24.98  ? 562 VAL B CB  1 
ATOM   7741 C  CG1 . VAL B 1 562 ? 134.509 131.069 160.111 1.00 24.98  ? 562 VAL B CG1 1 
ATOM   7742 C  CG2 . VAL B 1 562 ? 133.475 130.522 157.909 1.00 24.98  ? 562 VAL B CG2 1 
ATOM   7743 N  N   . ALA B 1 563 ? 132.323 128.974 162.087 1.00 26.00  ? 563 ALA B N   1 
ATOM   7744 C  CA  . ALA B 1 563 ? 132.396 128.805 163.534 1.00 26.00  ? 563 ALA B CA  1 
ATOM   7745 C  C   . ALA B 1 563 ? 132.687 127.357 163.909 1.00 26.00  ? 563 ALA B C   1 
ATOM   7746 O  O   . ALA B 1 563 ? 133.488 127.089 164.813 1.00 26.00  ? 563 ALA B O   1 
ATOM   7747 C  CB  . ALA B 1 563 ? 131.097 129.276 164.184 1.00 26.00  ? 563 ALA B CB  1 
ATOM   7748 N  N   . VAL B 1 564 ? 132.049 126.408 163.222 1.00 25.57  ? 564 VAL B N   1 
ATOM   7749 C  CA  . VAL B 1 564 ? 132.267 125.000 163.535 1.00 25.57  ? 564 VAL B CA  1 
ATOM   7750 C  C   . VAL B 1 564 ? 133.680 124.577 163.155 1.00 25.57  ? 564 VAL B C   1 
ATOM   7751 O  O   . VAL B 1 564 ? 134.310 123.780 163.858 1.00 25.57  ? 564 VAL B O   1 
ATOM   7752 C  CB  . VAL B 1 564 ? 131.203 124.128 162.847 1.00 25.57  ? 564 VAL B CB  1 
ATOM   7753 C  CG1 . VAL B 1 564 ? 131.548 122.660 162.988 1.00 25.57  ? 564 VAL B CG1 1 
ATOM   7754 C  CG2 . VAL B 1 564 ? 129.836 124.409 163.440 1.00 25.57  ? 564 VAL B CG2 1 
ATOM   7755 N  N   . VAL B 1 565 ? 134.205 125.097 162.043 1.00 29.59  ? 565 VAL B N   1 
ATOM   7756 C  CA  . VAL B 1 565 ? 135.586 124.797 161.668 1.00 29.59  ? 565 VAL B CA  1 
ATOM   7757 C  C   . VAL B 1 565 ? 136.553 125.342 162.713 1.00 29.59  ? 565 VAL B C   1 
ATOM   7758 O  O   . VAL B 1 565 ? 137.521 124.671 163.095 1.00 29.59  ? 565 VAL B O   1 
ATOM   7759 C  CB  . VAL B 1 565 ? 135.890 125.350 160.263 1.00 29.59  ? 565 VAL B CB  1 
ATOM   7760 C  CG1 . VAL B 1 565 ? 137.389 125.418 160.026 1.00 29.59  ? 565 VAL B CG1 1 
ATOM   7761 C  CG2 . VAL B 1 565 ? 135.225 124.487 159.207 1.00 29.59  ? 565 VAL B CG2 1 
ATOM   7762 N  N   . MET B 1 566 ? 136.308 126.565 163.190 1.00 33.64  ? 566 MET B N   1 
ATOM   7763 C  CA  . MET B 1 566 ? 137.129 127.130 164.258 1.00 33.64  ? 566 MET B CA  1 
ATOM   7764 C  C   . MET B 1 566 ? 137.093 126.250 165.502 1.00 33.64  ? 566 MET B C   1 
ATOM   7765 O  O   . MET B 1 566 ? 138.136 125.941 166.095 1.00 33.64  ? 566 MET B O   1 
ATOM   7766 C  CB  . MET B 1 566 ? 136.644 128.541 164.593 1.00 33.64  ? 566 MET B CB  1 
ATOM   7767 C  CG  . MET B 1 566 ? 136.891 129.576 163.514 1.00 33.64  ? 566 MET B CG  1 
ATOM   7768 S  SD  . MET B 1 566 ? 138.266 129.146 162.443 1.00 33.64  ? 566 MET B SD  1 
ATOM   7769 C  CE  . MET B 1 566 ? 139.618 129.728 163.459 1.00 33.64  ? 566 MET B CE  1 
ATOM   7770 N  N   . LEU B 1 567 ? 135.892 125.835 165.909 1.00 37.87  ? 567 LEU B N   1 
ATOM   7771 C  CA  . LEU B 1 567 ? 135.760 125.015 167.107 1.00 37.87  ? 567 LEU B CA  1 
ATOM   7772 C  C   . LEU B 1 567 ? 136.446 123.666 166.931 1.00 37.87  ? 567 LEU B C   1 
ATOM   7773 O  O   . LEU B 1 567 ? 137.065 123.149 167.867 1.00 37.87  ? 567 LEU B O   1 
ATOM   7774 C  CB  . LEU B 1 567 ? 134.283 124.829 167.454 1.00 37.87  ? 567 LEU B CB  1 
ATOM   7775 C  CG  . LEU B 1 567 ? 133.985 124.086 168.756 1.00 37.87  ? 567 LEU B CG  1 
ATOM   7776 C  CD1 . LEU B 1 567 ? 134.544 124.846 169.947 1.00 37.87  ? 567 LEU B CD1 1 
ATOM   7777 C  CD2 . LEU B 1 567 ? 132.492 123.856 168.914 1.00 37.87  ? 567 LEU B CD2 1 
ATOM   7778 N  N   . GLY B 1 568 ? 136.343 123.078 165.738 1.00 41.14  ? 568 GLY B N   1 
ATOM   7779 C  CA  . GLY B 1 568 ? 137.005 121.809 165.488 1.00 41.14  ? 568 GLY B CA  1 
ATOM   7780 C  C   . GLY B 1 568 ? 138.516 121.925 165.508 1.00 41.14  ? 568 GLY B C   1 
ATOM   7781 O  O   . GLY B 1 568 ? 139.207 121.052 166.040 1.00 41.14  ? 568 GLY B O   1 
ATOM   7782 N  N   . ILE B 1 569 ? 139.050 122.999 164.927 1.00 39.83  ? 569 ILE B N   1 
ATOM   7783 C  CA  . ILE B 1 569 ? 140.491 123.225 164.971 1.00 39.83  ? 569 ILE B CA  1 
ATOM   7784 C  C   . ILE B 1 569 ? 140.952 123.398 166.410 1.00 39.83  ? 569 ILE B C   1 
ATOM   7785 O  O   . ILE B 1 569 ? 142.000 122.878 166.811 1.00 39.83  ? 569 ILE B O   1 
ATOM   7786 C  CB  . ILE B 1 569 ? 140.868 124.436 164.098 1.00 39.83  ? 569 ILE B CB  1 
ATOM   7787 C  CG1 . ILE B 1 569 ? 140.971 124.017 162.634 1.00 39.83  ? 569 ILE B CG1 1 
ATOM   7788 C  CG2 . ILE B 1 569 ? 142.175 125.052 164.561 1.00 39.83  ? 569 ILE B CG2 1 
ATOM   7789 C  CD1 . ILE B 1 569 ? 142.129 123.087 162.354 1.00 39.83  ? 569 ILE B CD1 1 
ATOM   7790 N  N   . CYS B 1 570 ? 140.172 124.121 167.215 1.00 44.01  ? 570 CYS B N   1 
ATOM   7791 C  CA  . CYS B 1 570 ? 140.571 124.350 168.599 1.00 44.01  ? 570 CYS B CA  1 
ATOM   7792 C  C   . CYS B 1 570 ? 140.433 123.097 169.461 1.00 44.01  ? 570 CYS B C   1 
ATOM   7793 O  O   . CYS B 1 570 ? 141.211 122.915 170.403 1.00 44.01  ? 570 CYS B O   1 
ATOM   7794 C  CB  . CYS B 1 570 ? 139.753 125.494 169.197 1.00 44.01  ? 570 CYS B CB  1 
ATOM   7795 S  SG  . CYS B 1 570 ? 140.091 127.109 168.461 1.00 44.01  ? 570 CYS B SG  1 
ATOM   7796 N  N   . THR B 1 571 ? 139.463 122.228 169.169 1.00 47.48  ? 571 THR B N   1 
ATOM   7797 C  CA  . THR B 1 571 ? 139.088 121.168 170.098 1.00 47.48  ? 571 THR B CA  1 
ATOM   7798 C  C   . THR B 1 571 ? 139.371 119.761 169.582 1.00 47.48  ? 571 THR B C   1 
ATOM   7799 O  O   . THR B 1 571 ? 140.113 119.014 170.225 1.00 47.48  ? 571 THR B O   1 
ATOM   7800 C  CB  . THR B 1 571 ? 137.602 121.305 170.453 1.00 47.48  ? 571 THR B CB  1 
ATOM   7801 O  OG1 . THR B 1 571 ? 137.374 122.580 171.066 1.00 47.48  ? 571 THR B OG1 1 
ATOM   7802 C  CG2 . THR B 1 571 ? 137.182 120.208 171.416 1.00 47.48  ? 571 THR B CG2 1 
ATOM   7803 N  N   . TRP B 1 572 ? 138.807 119.366 168.439 1.00 53.60  ? 572 TRP B N   1 
ATOM   7804 C  CA  . TRP B 1 572 ? 138.841 117.955 168.065 1.00 53.60  ? 572 TRP B CA  1 
ATOM   7805 C  C   . TRP B 1 572 ? 140.044 117.551 167.225 1.00 53.60  ? 572 TRP B C   1 
ATOM   7806 O  O   . TRP B 1 572 ? 140.436 116.381 167.264 1.00 53.60  ? 572 TRP B O   1 
ATOM   7807 C  CB  . TRP B 1 572 ? 137.573 117.550 167.303 1.00 53.60  ? 572 TRP B CB  1 
ATOM   7808 C  CG  . TRP B 1 572 ? 136.314 117.551 168.117 1.00 53.60  ? 572 TRP B CG  1 
ATOM   7809 C  CD1 . TRP B 1 572 ? 135.816 116.509 168.845 1.00 53.60  ? 572 TRP B CD1 1 
ATOM   7810 C  CD2 . TRP B 1 572 ? 135.355 118.609 168.226 1.00 53.60  ? 572 TRP B CD2 1 
ATOM   7811 N  NE1 . TRP B 1 572 ? 134.628 116.866 169.435 1.00 53.60  ? 572 TRP B NE1 1 
ATOM   7812 C  CE2 . TRP B 1 572 ? 134.321 118.150 169.067 1.00 53.60  ? 572 TRP B CE2 1 
ATOM   7813 C  CE3 . TRP B 1 572 ? 135.277 119.903 167.709 1.00 53.60  ? 572 TRP B CE3 1 
ATOM   7814 C  CZ2 . TRP B 1 572 ? 133.224 118.941 169.403 1.00 53.60  ? 572 TRP B CZ2 1 
ATOM   7815 C  CZ3 . TRP B 1 572 ? 134.188 120.686 168.043 1.00 53.60  ? 572 TRP B CZ3 1 
ATOM   7816 C  CH2 . TRP B 1 572 ? 133.177 120.204 168.882 1.00 53.60  ? 572 TRP B CH2 1 
ATOM   7817 N  N   . ILE B 1 573 ? 140.641 118.466 166.467 1.00 45.95  ? 573 ILE B N   1 
ATOM   7818 C  CA  . ILE B 1 573 ? 141.623 118.073 165.456 1.00 45.95  ? 573 ILE B CA  1 
ATOM   7819 C  C   . ILE B 1 573 ? 143.032 117.973 166.034 1.00 45.95  ? 573 ILE B C   1 
ATOM   7820 O  O   . ILE B 1 573 ? 143.810 117.093 165.643 1.00 45.95  ? 573 ILE B O   1 
ATOM   7821 C  CB  . ILE B 1 573 ? 141.559 119.054 164.271 1.00 45.95  ? 573 ILE B CB  1 
ATOM   7822 C  CG1 . ILE B 1 573 ? 140.154 119.057 163.670 1.00 45.95  ? 573 ILE B CG1 1 
ATOM   7823 C  CG2 . ILE B 1 573 ? 142.566 118.674 163.209 1.00 45.95  ? 573 ILE B CG2 1 
ATOM   7824 C  CD1 . ILE B 1 573 ? 139.909 120.173 162.687 1.00 45.95  ? 573 ILE B CD1 1 
ATOM   7825 N  N   . VAL B 1 574 ? 143.378 118.855 166.966 1.00 46.55  ? 574 VAL B N   1 
ATOM   7826 C  CA  . VAL B 1 574 ? 144.724 118.899 167.535 1.00 46.55  ? 574 VAL B CA  1 
ATOM   7827 C  C   . VAL B 1 574 ? 145.083 117.655 168.349 1.00 46.55  ? 574 VAL B C   1 
ATOM   7828 O  O   . VAL B 1 574 ? 146.280 117.359 168.469 1.00 46.55  ? 574 VAL B O   1 
ATOM   7829 C  CB  . VAL B 1 574 ? 144.930 120.182 168.363 1.00 46.55  ? 574 VAL B CB  1 
ATOM   7830 C  CG1 . VAL B 1 574 ? 144.788 121.403 167.472 1.00 46.55  ? 574 VAL B CG1 1 
ATOM   7831 C  CG2 . VAL B 1 574 ? 143.957 120.272 169.523 1.00 46.55  ? 574 VAL B CG2 1 
ATOM   7832 N  N   . PRO B 1 575 ? 144.130 116.884 168.942 1.00 48.24  ? 575 PRO B N   1 
ATOM   7833 C  CA  . PRO B 1 575 ? 144.551 115.630 169.585 1.00 48.24  ? 575 PRO B CA  1 
ATOM   7834 C  C   . PRO B 1 575 ? 145.157 114.619 168.623 1.00 48.24  ? 575 PRO B C   1 
ATOM   7835 O  O   . PRO B 1 575 ? 146.239 114.092 168.896 1.00 48.24  ? 575 PRO B O   1 
ATOM   7836 C  CB  . PRO B 1 575 ? 143.253 115.097 170.206 1.00 48.24  ? 575 PRO B CB  1 
ATOM   7837 C  CG  . PRO B 1 575 ? 142.443 116.293 170.435 1.00 48.24  ? 575 PRO B CG  1 
ATOM   7838 C  CD  . PRO B 1 575 ? 142.716 117.167 169.259 1.00 48.24  ? 575 PRO B CD  1 
ATOM   7839 N  N   . MET B 1 576 ? 144.489 114.327 167.503 1.00 47.46  ? 576 MET B N   1 
ATOM   7840 C  CA  . MET B 1 576 ? 145.005 113.267 166.642 1.00 47.46  ? 576 MET B CA  1 
ATOM   7841 C  C   . MET B 1 576 ? 146.035 113.783 165.643 1.00 47.46  ? 576 MET B C   1 
ATOM   7842 O  O   . MET B 1 576 ? 146.989 113.066 165.322 1.00 47.46  ? 576 MET B O   1 
ATOM   7843 C  CB  . MET B 1 576 ? 143.870 112.541 165.912 1.00 47.46  ? 576 MET B CB  1 
ATOM   7844 C  CG  . MET B 1 576 ? 143.180 113.314 164.806 1.00 47.46  ? 576 MET B CG  1 
ATOM   7845 S  SD  . MET B 1 576 ? 142.046 114.557 165.423 1.00 47.46  ? 576 MET B SD  1 
ATOM   7846 C  CE  . MET B 1 576 ? 140.600 113.550 165.740 1.00 47.46  ? 576 MET B CE  1 
ATOM   7847 N  N   . PHE B 1 577 ? 145.881 115.008 165.135 1.00 46.66  ? 577 PHE B N   1 
ATOM   7848 C  CA  . PHE B 1 577 ? 146.869 115.499 164.181 1.00 46.66  ? 577 PHE B CA  1 
ATOM   7849 C  C   . PHE B 1 577 ? 148.060 116.184 164.835 1.00 46.66  ? 577 PHE B C   1 
ATOM   7850 O  O   . PHE B 1 577 ? 149.040 116.467 164.139 1.00 46.66  ? 577 PHE B O   1 
ATOM   7851 C  CB  . PHE B 1 577 ? 146.225 116.450 163.167 1.00 46.66  ? 577 PHE B CB  1 
ATOM   7852 C  CG  . PHE B 1 577 ? 145.400 115.754 162.126 1.00 46.66  ? 577 PHE B CG  1 
ATOM   7853 C  CD1 . PHE B 1 577 ? 145.506 114.387 161.944 1.00 46.66  ? 577 PHE B CD1 1 
ATOM   7854 C  CD2 . PHE B 1 577 ? 144.534 116.466 161.316 1.00 46.66  ? 577 PHE B CD2 1 
ATOM   7855 C  CE1 . PHE B 1 577 ? 144.755 113.741 160.984 1.00 46.66  ? 577 PHE B CE1 1 
ATOM   7856 C  CE2 . PHE B 1 577 ? 143.780 115.826 160.354 1.00 46.66  ? 577 PHE B CE2 1 
ATOM   7857 C  CZ  . PHE B 1 577 ? 143.891 114.462 160.187 1.00 46.66  ? 577 PHE B CZ  1 
ATOM   7858 N  N   . ASP B 1 578 ? 148.011 116.434 166.143 1.00 54.40  ? 578 ASP B N   1 
ATOM   7859 C  CA  . ASP B 1 578 ? 149.125 117.025 166.883 1.00 54.40  ? 578 ASP B CA  1 
ATOM   7860 C  C   . ASP B 1 578 ? 149.579 118.332 166.225 1.00 54.40  ? 578 ASP B C   1 
ATOM   7861 O  O   . ASP B 1 578 ? 150.708 118.485 165.760 1.00 54.40  ? 578 ASP B O   1 
ATOM   7862 C  CB  . ASP B 1 578 ? 150.271 116.016 167.003 1.00 54.40  ? 578 ASP B CB  1 
ATOM   7863 C  CG  . ASP B 1 578 ? 151.397 116.514 167.877 1.00 54.40  ? 578 ASP B CG  1 
ATOM   7864 O  OD1 . ASP B 1 578 ? 151.226 116.539 169.113 1.00 54.40  ? 578 ASP B OD1 1 
ATOM   7865 O  OD2 . ASP B 1 578 ? 152.460 116.864 167.324 1.00 54.40  ? 578 ASP B OD2 1 
ATOM   7866 N  N   . LEU B 1 579 ? 148.643 119.276 166.199 1.00 50.26  ? 579 LEU B N   1 
ATOM   7867 C  CA  . LEU B 1 579 ? 148.797 120.520 165.460 1.00 50.26  ? 579 LEU B CA  1 
ATOM   7868 C  C   . LEU B 1 579 ? 149.507 121.612 166.247 1.00 50.26  ? 579 LEU B C   1 
ATOM   7869 O  O   . LEU B 1 579 ? 149.717 122.702 165.707 1.00 50.26  ? 579 LEU B O   1 
ATOM   7870 C  CB  . LEU B 1 579 ? 147.423 121.029 165.016 1.00 50.26  ? 579 LEU B CB  1 
ATOM   7871 C  CG  . LEU B 1 579 ? 146.660 120.169 164.012 1.00 50.26  ? 579 LEU B CG  1 
ATOM   7872 C  CD1 . LEU B 1 579 ? 145.465 120.927 163.471 1.00 50.26  ? 579 LEU B CD1 1 
ATOM   7873 C  CD2 . LEU B 1 579 ? 147.571 119.748 162.882 1.00 50.26  ? 579 LEU B CD2 1 
ATOM   7874 N  N   . TYR B 1 580 ? 149.879 121.360 167.500 1.00 60.02  ? 580 TYR B N   1 
ATOM   7875 C  CA  . TYR B 1 580 ? 150.421 122.429 168.329 1.00 60.02  ? 580 TYR B CA  1 
ATOM   7876 C  C   . TYR B 1 580 ? 151.939 122.542 168.244 1.00 60.02  ? 580 TYR B C   1 
ATOM   7877 O  O   . TYR B 1 580 ? 152.487 123.628 168.456 1.00 60.02  ? 580 TYR B O   1 
ATOM   7878 C  CB  . TYR B 1 580 ? 149.989 122.232 169.783 1.00 60.02  ? 580 TYR B CB  1 
ATOM   7879 C  CG  . TYR B 1 580 ? 148.722 122.978 170.129 1.00 60.02  ? 580 TYR B CG  1 
ATOM   7880 C  CD1 . TYR B 1 580 ? 147.476 122.431 169.853 1.00 60.02  ? 580 TYR B CD1 1 
ATOM   7881 C  CD2 . TYR B 1 580 ? 148.770 124.231 170.724 1.00 60.02  ? 580 TYR B CD2 1 
ATOM   7882 C  CE1 . TYR B 1 580 ? 146.315 123.110 170.162 1.00 60.02  ? 580 TYR B CE1 1 
ATOM   7883 C  CE2 . TYR B 1 580 ? 147.613 124.916 171.038 1.00 60.02  ? 580 TYR B CE2 1 
ATOM   7884 C  CZ  . TYR B 1 580 ? 146.388 124.350 170.754 1.00 60.02  ? 580 TYR B CZ  1 
ATOM   7885 O  OH  . TYR B 1 580 ? 145.232 125.026 171.063 1.00 60.02  ? 580 TYR B OH  1 
ATOM   7886 N  N   . THR B 1 581 ? 152.635 121.452 167.938 1.00 62.66  ? 581 THR B N   1 
ATOM   7887 C  CA  . THR B 1 581 ? 154.086 121.471 167.838 1.00 62.66  ? 581 THR B CA  1 
ATOM   7888 C  C   . THR B 1 581 ? 154.527 121.172 166.411 1.00 62.66  ? 581 THR B C   1 
ATOM   7889 O  O   . THR B 1 581 ? 153.813 120.533 165.633 1.00 62.66  ? 581 THR B O   1 
ATOM   7890 C  CB  . THR B 1 581 ? 154.723 120.470 168.810 1.00 62.66  ? 581 THR B CB  1 
ATOM   7891 O  OG1 . THR B 1 581 ? 156.143 120.665 168.838 1.00 62.66  ? 581 THR B OG1 1 
ATOM   7892 C  CG2 . THR B 1 581 ? 154.425 119.047 168.388 1.00 62.66  ? 581 THR B CG2 1 
ATOM   7893 N  N   . TYR B 1 582 ? 155.715 121.658 166.075 1.00 63.35  ? 582 TYR B N   1 
ATOM   7894 C  CA  . TYR B 1 582 ? 156.260 121.460 164.738 1.00 63.35  ? 582 TYR B CA  1 
ATOM   7895 C  C   . TYR B 1 582 ? 156.572 119.985 164.515 1.00 63.35  ? 582 TYR B C   1 
ATOM   7896 O  O   . TYR B 1 582 ? 157.246 119.367 165.347 1.00 63.35  ? 582 TYR B O   1 
ATOM   7897 C  CB  . TYR B 1 582 ? 157.520 122.302 164.554 1.00 63.35  ? 582 TYR B CB  1 
ATOM   7898 C  CG  . TYR B 1 582 ? 157.858 122.614 163.114 1.00 63.35  ? 582 TYR B CG  1 
ATOM   7899 C  CD1 . TYR B 1 582 ? 156.902 123.123 162.249 1.00 63.35  ? 582 TYR B CD1 1 
ATOM   7900 C  CD2 . TYR B 1 582 ? 159.139 122.408 162.624 1.00 63.35  ? 582 TYR B CD2 1 
ATOM   7901 C  CE1 . TYR B 1 582 ? 157.207 123.414 160.937 1.00 63.35  ? 582 TYR B CE1 1 
ATOM   7902 C  CE2 . TYR B 1 582 ? 159.454 122.696 161.312 1.00 63.35  ? 582 TYR B CE2 1 
ATOM   7903 C  CZ  . TYR B 1 582 ? 158.485 123.198 160.474 1.00 63.35  ? 582 TYR B CZ  1 
ATOM   7904 O  OH  . TYR B 1 582 ? 158.797 123.485 159.166 1.00 63.35  ? 582 TYR B OH  1 
ATOM   7905 N  N   . PRO B 1 583 ? 156.111 119.390 163.420 1.00 62.62  ? 583 PRO B N   1 
ATOM   7906 C  CA  . PRO B 1 583 ? 156.362 117.970 163.175 1.00 62.62  ? 583 PRO B CA  1 
ATOM   7907 C  C   . PRO B 1 583 ? 157.699 117.729 162.487 1.00 62.62  ? 583 PRO B C   1 
ATOM   7908 O  O   . PRO B 1 583 ? 158.334 118.639 161.950 1.00 62.62  ? 583 PRO B O   1 
ATOM   7909 C  CB  . PRO B 1 583 ? 155.197 117.560 162.261 1.00 62.62  ? 583 PRO B CB  1 
ATOM   7910 C  CG  . PRO B 1 583 ? 154.592 118.855 161.749 1.00 62.62  ? 583 PRO B CG  1 
ATOM   7911 C  CD  . PRO B 1 583 ? 155.347 120.009 162.328 1.00 62.62  ? 583 PRO B CD  1 
ATOM   7912 N  N   . SER B 1 584 ? 158.118 116.463 162.518 1.00 63.78  ? 584 SER B N   1 
ATOM   7913 C  CA  . SER B 1 584 ? 159.398 116.094 161.926 1.00 63.78  ? 584 SER B CA  1 
ATOM   7914 C  C   . SER B 1 584 ? 159.353 116.172 160.405 1.00 63.78  ? 584 SER B C   1 
ATOM   7915 O  O   . SER B 1 584 ? 160.326 116.597 159.772 1.00 63.78  ? 584 SER B O   1 
ATOM   7916 C  CB  . SER B 1 584 ? 159.799 114.691 162.377 1.00 63.78  ? 584 SER B CB  1 
ATOM   7917 O  OG  . SER B 1 584 ? 158.971 113.707 161.782 1.00 63.78  ? 584 SER B OG  1 
ATOM   7918 N  N   . TRP B 1 585 ? 158.234 115.764 159.799 1.00 59.27  ? 585 TRP B N   1 
ATOM   7919 C  CA  . TRP B 1 585 ? 158.155 115.716 158.344 1.00 59.27  ? 585 TRP B CA  1 
ATOM   7920 C  C   . TRP B 1 585 ? 158.178 117.100 157.709 1.00 59.27  ? 585 TRP B C   1 
ATOM   7921 O  O   . TRP B 1 585 ? 158.536 117.220 156.533 1.00 59.27  ? 585 TRP B O   1 
ATOM   7922 C  CB  . TRP B 1 585 ? 156.901 114.962 157.901 1.00 59.27  ? 585 TRP B CB  1 
ATOM   7923 C  CG  . TRP B 1 585 ? 155.669 115.282 158.687 1.00 59.27  ? 585 TRP B CG  1 
ATOM   7924 C  CD1 . TRP B 1 585 ? 155.221 114.640 159.803 1.00 59.27  ? 585 TRP B CD1 1 
ATOM   7925 C  CD2 . TRP B 1 585 ? 154.713 116.310 158.405 1.00 59.27  ? 585 TRP B CD2 1 
ATOM   7926 N  NE1 . TRP B 1 585 ? 154.050 115.210 160.239 1.00 59.27  ? 585 TRP B NE1 1 
ATOM   7927 C  CE2 . TRP B 1 585 ? 153.716 116.237 159.396 1.00 59.27  ? 585 TRP B CE2 1 
ATOM   7928 C  CE3 . TRP B 1 585 ? 154.604 117.286 157.411 1.00 59.27  ? 585 TRP B CE3 1 
ATOM   7929 C  CZ2 . TRP B 1 585 ? 152.627 117.104 159.425 1.00 59.27  ? 585 TRP B CZ2 1 
ATOM   7930 C  CZ3 . TRP B 1 585 ? 153.521 118.147 157.442 1.00 59.27  ? 585 TRP B CZ3 1 
ATOM   7931 C  CH2 . TRP B 1 585 ? 152.548 118.050 158.441 1.00 59.27  ? 585 TRP B CH2 1 
ATOM   7932 N  N   . ALA B 1 586 ? 157.801 118.137 158.448 1.00 62.25  ? 586 ALA B N   1 
ATOM   7933 C  CA  . ALA B 1 586 ? 157.873 119.487 157.911 1.00 62.25  ? 586 ALA B CA  1 
ATOM   7934 C  C   . ALA B 1 586 ? 159.333 119.910 157.754 1.00 62.25  ? 586 ALA B C   1 
ATOM   7935 O  O   . ALA B 1 586 ? 160.179 119.536 158.572 1.00 62.25  ? 586 ALA B O   1 
ATOM   7936 C  CB  . ALA B 1 586 ? 157.136 120.467 158.820 1.00 62.25  ? 586 ALA B CB  1 
ATOM   7937 N  N   . PRO B 1 587 ? 159.660 120.675 156.713 1.00 64.14  ? 587 PRO B N   1 
ATOM   7938 C  CA  . PRO B 1 587 ? 161.048 121.115 156.530 1.00 64.14  ? 587 PRO B CA  1 
ATOM   7939 C  C   . PRO B 1 587 ? 161.521 121.973 157.694 1.00 64.14  ? 587 PRO B C   1 
ATOM   7940 O  O   . PRO B 1 587 ? 160.754 122.744 158.275 1.00 64.14  ? 587 PRO B O   1 
ATOM   7941 C  CB  . PRO B 1 587 ? 160.998 121.917 155.224 1.00 64.14  ? 587 PRO B CB  1 
ATOM   7942 C  CG  . PRO B 1 587 ? 159.762 121.448 154.529 1.00 64.14  ? 587 PRO B CG  1 
ATOM   7943 C  CD  . PRO B 1 587 ? 158.788 121.120 155.615 1.00 64.14  ? 587 PRO B CD  1 
ATOM   7944 N  N   . ALA B 1 588 ? 162.798 121.832 158.029 1.00 61.87  ? 588 ALA B N   1 
ATOM   7945 C  CA  . ALA B 1 588 ? 163.391 122.588 159.125 1.00 61.87  ? 588 ALA B CA  1 
ATOM   7946 C  C   . ALA B 1 588 ? 163.846 123.965 158.655 1.00 61.87  ? 588 ALA B C   1 
ATOM   7947 O  O   . ALA B 1 588 ? 163.337 124.988 159.114 1.00 61.87  ? 588 ALA B O   1 
ATOM   7948 C  CB  . ALA B 1 588 ? 164.556 121.821 159.728 1.00 61.87  ? 588 ALA B CB  1 
HETATM 7949 NA NA  . NA  C 2 .   ? 130.158 121.799 105.683 1.00 37.43  ? 601 NA  A NA  1 
HETATM 7950 S  S   . SO4 D 3 .   ? 129.484 130.537 109.455 1.00 30.00  ? 602 SO4 A S   1 
HETATM 7951 O  O1  . SO4 D 3 .   ? 129.794 131.498 108.402 1.00 30.00  ? 602 SO4 A O1  1 
HETATM 7952 O  O2  . SO4 D 3 .   ? 128.045 130.523 109.720 1.00 30.00  ? 602 SO4 A O2  1 
HETATM 7953 O  O3  . SO4 D 3 .   ? 129.893 129.203 109.009 1.00 30.00  ? 602 SO4 A O3  1 
HETATM 7954 O  O4  . SO4 D 3 .   ? 130.198 130.930 110.671 1.00 30.00  ? 602 SO4 A O4  1 
HETATM 7955 NA NA  . NA  E 2 .   ? 130.422 114.869 147.150 1.00 27.19  ? 901 NA  B NA  1 
HETATM 7956 NA NA  . NA  F 2 .   ? 133.217 128.560 144.686 1.00 31.38  ? 902 NA  B NA  1 
HETATM 7957 S  S   . SO4 G 3 .   ? 132.481 118.728 142.810 1.00 47.89  ? 903 SO4 B S   1 
HETATM 7958 O  O1  . SO4 G 3 .   ? 133.634 119.037 141.973 1.00 47.89  ? 903 SO4 B O1  1 
HETATM 7959 O  O2  . SO4 G 3 .   ? 132.936 118.359 144.145 1.00 47.89  ? 903 SO4 B O2  1 
HETATM 7960 O  O3  . SO4 G 3 .   ? 131.614 119.897 142.898 1.00 47.89  ? 903 SO4 B O3  1 
HETATM 7961 O  O4  . SO4 G 3 .   ? 131.742 117.617 142.222 1.00 47.89  ? 903 SO4 B O4  1 
# 
