data_8Y2N
# 
_entry.id   8Y2N 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Y2N         pdb_00008y2n 10.2210/pdb8y2n/pdb 
WWPDB D_1300044718 ?            ?                   
EMDB  EMD-38858    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Y2N 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Cryo-EM structure of the apo Lac1-Lip1 complex'       EMD-38858 'associated EM volume' 
EMDB 'Cryo-EM structure of the FB1-bound Lac1-Lip1 complex' EMD-38857 'other EM volume'      
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gongx@sustech.edu.cn 
_pdbx_contact_author.name_first         Xin 
_pdbx_contact_author.name_last          Gong 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3469-7718 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Xie, T.'   1 ? 
'Zhang, Z.' 2 ? 
'Fang, Q.'  3 ? 
'Gong, X.'  4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Structure 
_citation.journal_id_ASTM           STRUE6 
_citation.journal_id_CSD            2005 
_citation.journal_id_ISSN           0969-2126 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            32 
_citation.language                  ? 
_citation.page_first                1419 
_citation.page_last                 1428.e4 
_citation.title                     'Mechanism of ceramide synthase inhibition by fumonisin B 1.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.str.2024.06.002 
_citation.pdbx_database_id_PubMed   38964337 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhang, Z.' 1 ? 
primary 'Fang, Q.'  2 ? 
primary 'Xie, T.'   3 ? 
primary 'Gong, X.'  4 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Ceramide synthase LAC1' 50289.082 2 2.3.1.297 ? ? ? 
2 polymer     man 'Ceramide synthase subunit LIP1' 17228.682 2 ?         ? ? ? 
3 non-polymer syn 
'(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 763.100   8 ? 
? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Very-long-chain ceramide synthase LAC1' 
2 'LAG1/LAC1-interacting protein 1'        
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISY
RHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAI
RLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVL
QLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDSGLAFFSFAIFVVAWIYLRHY
INLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILKDDRSDSESDEE
SDESSTTPTDSTPTKKDILEDYKDDDDK
;
;MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISY
RHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAI
RLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVL
QLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDSGLAFFSFAIFVVAWIYLRHY
INLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILKDDRSDSESDEE
SDESSTTPTDSTPTKKDILEDYKDDDDK
;
A,C ? 
2 'polypeptide(L)' no no 
;MSQPTPIITTKSAAKPKPKIFNLFRVCFISLLLIAAVEYFKYGTRINYEWFHCTPIKEPQSGSVIKLWARGGPSCDKRGE
YKTIVKRITRDYEPNDEHLSFCIIENDNVPPVHYPIHEDKGEPGYVAYVGYDTDSELVQELCADSTIYHM
;
;MSQPTPIITTKSAAKPKPKIFNLFRVCFISLLLIAAVEYFKYGTRINYEWFHCTPIKEPQSGSVIKLWARGGPSCDKRGE
YKTIVKRITRDYEPNDEHLSFCIIENDNVPPVHYPIHEDKGEPGYVAYVGYDTDSELVQELCADSTIYHM
;
B,D ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        
'(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 
_pdbx_entity_nonpoly.comp_id     6PL 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   THR n 
1 4   ILE n 
1 5   LYS n 
1 6   PRO n 
1 7   SER n 
1 8   PRO n 
1 9   SER n 
1 10  ASN n 
1 11  ASN n 
1 12  ASN n 
1 13  LEU n 
1 14  LYS n 
1 15  VAL n 
1 16  ARG n 
1 17  SER n 
1 18  ARG n 
1 19  PRO n 
1 20  ARG n 
1 21  ARG n 
1 22  LYS n 
1 23  SER n 
1 24  SER n 
1 25  ILE n 
1 26  GLY n 
1 27  LYS n 
1 28  ILE n 
1 29  ASP n 
1 30  LEU n 
1 31  GLY n 
1 32  ASP n 
1 33  THR n 
1 34  VAL n 
1 35  PRO n 
1 36  SER n 
1 37  LEU n 
1 38  GLY n 
1 39  THR n 
1 40  MET n 
1 41  PHE n 
1 42  GLU n 
1 43  THR n 
1 44  LYS n 
1 45  GLU n 
1 46  SER n 
1 47  LYS n 
1 48  THR n 
1 49  ALA n 
1 50  ALA n 
1 51  LYS n 
1 52  ARG n 
1 53  ARG n 
1 54  MET n 
1 55  GLN n 
1 56  ARG n 
1 57  LEU n 
1 58  SER n 
1 59  GLU n 
1 60  ALA n 
1 61  THR n 
1 62  LYS n 
1 63  ASN n 
1 64  ASP n 
1 65  SER n 
1 66  ASP n 
1 67  LEU n 
1 68  VAL n 
1 69  LYS n 
1 70  LYS n 
1 71  ILE n 
1 72  TRP n 
1 73  PHE n 
1 74  SER n 
1 75  PHE n 
1 76  ARG n 
1 77  GLU n 
1 78  ILE n 
1 79  SER n 
1 80  TYR n 
1 81  ARG n 
1 82  HIS n 
1 83  ALA n 
1 84  TRP n 
1 85  ILE n 
1 86  ALA n 
1 87  PRO n 
1 88  LEU n 
1 89  MET n 
1 90  ILE n 
1 91  LEU n 
1 92  ILE n 
1 93  ALA n 
1 94  VAL n 
1 95  TYR n 
1 96  SER n 
1 97  ALA n 
1 98  TYR n 
1 99  PHE n 
1 100 THR n 
1 101 SER n 
1 102 GLY n 
1 103 ASN n 
1 104 THR n 
1 105 THR n 
1 106 LYS n 
1 107 THR n 
1 108 ASN n 
1 109 VAL n 
1 110 LEU n 
1 111 HIS n 
1 112 ARG n 
1 113 PHE n 
1 114 VAL n 
1 115 ALA n 
1 116 VAL n 
1 117 SER n 
1 118 TYR n 
1 119 GLN n 
1 120 ILE n 
1 121 GLY n 
1 122 ASP n 
1 123 THR n 
1 124 ASN n 
1 125 ALA n 
1 126 TYR n 
1 127 GLY n 
1 128 LYS n 
1 129 GLY n 
1 130 ILE n 
1 131 ASN n 
1 132 ASP n 
1 133 LEU n 
1 134 CYS n 
1 135 PHE n 
1 136 VAL n 
1 137 PHE n 
1 138 TYR n 
1 139 TYR n 
1 140 MET n 
1 141 ILE n 
1 142 PHE n 
1 143 PHE n 
1 144 THR n 
1 145 PHE n 
1 146 LEU n 
1 147 ARG n 
1 148 GLU n 
1 149 PHE n 
1 150 LEU n 
1 151 MET n 
1 152 ASP n 
1 153 VAL n 
1 154 VAL n 
1 155 ILE n 
1 156 ARG n 
1 157 PRO n 
1 158 PHE n 
1 159 ALA n 
1 160 ILE n 
1 161 ARG n 
1 162 LEU n 
1 163 HIS n 
1 164 VAL n 
1 165 THR n 
1 166 SER n 
1 167 LYS n 
1 168 HIS n 
1 169 ARG n 
1 170 ILE n 
1 171 LYS n 
1 172 ARG n 
1 173 ILE n 
1 174 MET n 
1 175 GLU n 
1 176 GLN n 
1 177 MET n 
1 178 TYR n 
1 179 ALA n 
1 180 ILE n 
1 181 PHE n 
1 182 TYR n 
1 183 THR n 
1 184 GLY n 
1 185 VAL n 
1 186 SER n 
1 187 GLY n 
1 188 PRO n 
1 189 PHE n 
1 190 GLY n 
1 191 ILE n 
1 192 TYR n 
1 193 CYS n 
1 194 MET n 
1 195 TYR n 
1 196 HIS n 
1 197 SER n 
1 198 ASP n 
1 199 LEU n 
1 200 TRP n 
1 201 PHE n 
1 202 PHE n 
1 203 ASN n 
1 204 THR n 
1 205 LYS n 
1 206 ALA n 
1 207 MET n 
1 208 TYR n 
1 209 ARG n 
1 210 THR n 
1 211 TYR n 
1 212 PRO n 
1 213 ASP n 
1 214 PHE n 
1 215 THR n 
1 216 ASN n 
1 217 PRO n 
1 218 PHE n 
1 219 LEU n 
1 220 PHE n 
1 221 LYS n 
1 222 VAL n 
1 223 PHE n 
1 224 TYR n 
1 225 LEU n 
1 226 GLY n 
1 227 GLN n 
1 228 ALA n 
1 229 ALA n 
1 230 PHE n 
1 231 TRP n 
1 232 ALA n 
1 233 GLN n 
1 234 GLN n 
1 235 ALA n 
1 236 CYS n 
1 237 ILE n 
1 238 LEU n 
1 239 VAL n 
1 240 LEU n 
1 241 GLN n 
1 242 LEU n 
1 243 GLU n 
1 244 LYS n 
1 245 PRO n 
1 246 ARG n 
1 247 LYS n 
1 248 ASP n 
1 249 HIS n 
1 250 ASN n 
1 251 GLU n 
1 252 LEU n 
1 253 THR n 
1 254 PHE n 
1 255 HIS n 
1 256 HIS n 
1 257 ILE n 
1 258 VAL n 
1 259 THR n 
1 260 LEU n 
1 261 LEU n 
1 262 LEU n 
1 263 ILE n 
1 264 TRP n 
1 265 SER n 
1 266 SER n 
1 267 TYR n 
1 268 VAL n 
1 269 PHE n 
1 270 HIS n 
1 271 PHE n 
1 272 THR n 
1 273 LYS n 
1 274 MET n 
1 275 GLY n 
1 276 LEU n 
1 277 PRO n 
1 278 ILE n 
1 279 TYR n 
1 280 ILE n 
1 281 THR n 
1 282 MET n 
1 283 ASP n 
1 284 VAL n 
1 285 SER n 
1 286 ASP n 
1 287 PHE n 
1 288 LEU n 
1 289 LEU n 
1 290 SER n 
1 291 PHE n 
1 292 SER n 
1 293 LYS n 
1 294 THR n 
1 295 LEU n 
1 296 ASN n 
1 297 TYR n 
1 298 LEU n 
1 299 ASP n 
1 300 SER n 
1 301 GLY n 
1 302 LEU n 
1 303 ALA n 
1 304 PHE n 
1 305 PHE n 
1 306 SER n 
1 307 PHE n 
1 308 ALA n 
1 309 ILE n 
1 310 PHE n 
1 311 VAL n 
1 312 VAL n 
1 313 ALA n 
1 314 TRP n 
1 315 ILE n 
1 316 TYR n 
1 317 LEU n 
1 318 ARG n 
1 319 HIS n 
1 320 TYR n 
1 321 ILE n 
1 322 ASN n 
1 323 LEU n 
1 324 LYS n 
1 325 ILE n 
1 326 LEU n 
1 327 TRP n 
1 328 SER n 
1 329 VAL n 
1 330 LEU n 
1 331 THR n 
1 332 GLN n 
1 333 PHE n 
1 334 ARG n 
1 335 THR n 
1 336 GLU n 
1 337 GLY n 
1 338 ASN n 
1 339 TYR n 
1 340 VAL n 
1 341 LEU n 
1 342 ASN n 
1 343 PHE n 
1 344 ALA n 
1 345 THR n 
1 346 GLN n 
1 347 GLN n 
1 348 TYR n 
1 349 LYS n 
1 350 CYS n 
1 351 TRP n 
1 352 ILE n 
1 353 SER n 
1 354 LEU n 
1 355 PRO n 
1 356 ILE n 
1 357 VAL n 
1 358 PHE n 
1 359 VAL n 
1 360 LEU n 
1 361 ILE n 
1 362 GLY n 
1 363 ALA n 
1 364 LEU n 
1 365 GLN n 
1 366 LEU n 
1 367 VAL n 
1 368 ASN n 
1 369 LEU n 
1 370 TYR n 
1 371 TRP n 
1 372 LEU n 
1 373 PHE n 
1 374 LEU n 
1 375 ILE n 
1 376 PHE n 
1 377 ARG n 
1 378 VAL n 
1 379 LEU n 
1 380 TYR n 
1 381 ARG n 
1 382 ILE n 
1 383 LEU n 
1 384 TRP n 
1 385 ARG n 
1 386 GLY n 
1 387 ILE n 
1 388 LEU n 
1 389 LYS n 
1 390 ASP n 
1 391 ASP n 
1 392 ARG n 
1 393 SER n 
1 394 ASP n 
1 395 SER n 
1 396 GLU n 
1 397 SER n 
1 398 ASP n 
1 399 GLU n 
1 400 GLU n 
1 401 SER n 
1 402 ASP n 
1 403 GLU n 
1 404 SER n 
1 405 SER n 
1 406 THR n 
1 407 THR n 
1 408 PRO n 
1 409 THR n 
1 410 ASP n 
1 411 SER n 
1 412 THR n 
1 413 PRO n 
1 414 THR n 
1 415 LYS n 
1 416 LYS n 
1 417 ASP n 
1 418 ILE n 
1 419 LEU n 
1 420 GLU n 
1 421 ASP n 
1 422 TYR n 
1 423 LYS n 
1 424 ASP n 
1 425 ASP n 
1 426 ASP n 
1 427 ASP n 
1 428 LYS n 
2 1   MET n 
2 2   SER n 
2 3   GLN n 
2 4   PRO n 
2 5   THR n 
2 6   PRO n 
2 7   ILE n 
2 8   ILE n 
2 9   THR n 
2 10  THR n 
2 11  LYS n 
2 12  SER n 
2 13  ALA n 
2 14  ALA n 
2 15  LYS n 
2 16  PRO n 
2 17  LYS n 
2 18  PRO n 
2 19  LYS n 
2 20  ILE n 
2 21  PHE n 
2 22  ASN n 
2 23  LEU n 
2 24  PHE n 
2 25  ARG n 
2 26  VAL n 
2 27  CYS n 
2 28  PHE n 
2 29  ILE n 
2 30  SER n 
2 31  LEU n 
2 32  LEU n 
2 33  LEU n 
2 34  ILE n 
2 35  ALA n 
2 36  ALA n 
2 37  VAL n 
2 38  GLU n 
2 39  TYR n 
2 40  PHE n 
2 41  LYS n 
2 42  TYR n 
2 43  GLY n 
2 44  THR n 
2 45  ARG n 
2 46  ILE n 
2 47  ASN n 
2 48  TYR n 
2 49  GLU n 
2 50  TRP n 
2 51  PHE n 
2 52  HIS n 
2 53  CYS n 
2 54  THR n 
2 55  PRO n 
2 56  ILE n 
2 57  LYS n 
2 58  GLU n 
2 59  PRO n 
2 60  GLN n 
2 61  SER n 
2 62  GLY n 
2 63  SER n 
2 64  VAL n 
2 65  ILE n 
2 66  LYS n 
2 67  LEU n 
2 68  TRP n 
2 69  ALA n 
2 70  ARG n 
2 71  GLY n 
2 72  GLY n 
2 73  PRO n 
2 74  SER n 
2 75  CYS n 
2 76  ASP n 
2 77  LYS n 
2 78  ARG n 
2 79  GLY n 
2 80  GLU n 
2 81  TYR n 
2 82  LYS n 
2 83  THR n 
2 84  ILE n 
2 85  VAL n 
2 86  LYS n 
2 87  ARG n 
2 88  ILE n 
2 89  THR n 
2 90  ARG n 
2 91  ASP n 
2 92  TYR n 
2 93  GLU n 
2 94  PRO n 
2 95  ASN n 
2 96  ASP n 
2 97  GLU n 
2 98  HIS n 
2 99  LEU n 
2 100 SER n 
2 101 PHE n 
2 102 CYS n 
2 103 ILE n 
2 104 ILE n 
2 105 GLU n 
2 106 ASN n 
2 107 ASP n 
2 108 ASN n 
2 109 VAL n 
2 110 PRO n 
2 111 PRO n 
2 112 VAL n 
2 113 HIS n 
2 114 TYR n 
2 115 PRO n 
2 116 ILE n 
2 117 HIS n 
2 118 GLU n 
2 119 ASP n 
2 120 LYS n 
2 121 GLY n 
2 122 GLU n 
2 123 PRO n 
2 124 GLY n 
2 125 TYR n 
2 126 VAL n 
2 127 ALA n 
2 128 TYR n 
2 129 VAL n 
2 130 GLY n 
2 131 TYR n 
2 132 ASP n 
2 133 THR n 
2 134 ASP n 
2 135 SER n 
2 136 GLU n 
2 137 LEU n 
2 138 VAL n 
2 139 GLN n 
2 140 GLU n 
2 141 LEU n 
2 142 CYS n 
2 143 ALA n 
2 144 ASP n 
2 145 SER n 
2 146 THR n 
2 147 ILE n 
2 148 TYR n 
2 149 HIS n 
2 150 MET n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 428 
;Baker's yeast
;
? 'LAC1, DGT1, YKL008C, YKL156' ? ? ? ? ? ? 'Saccharomyces cerevisiae S288C' 559292 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 150 
;Baker's yeast
;
? 'LIP1, YMR298W'               ? ? ? ? ? ? 'Saccharomyces cerevisiae S288C' 559292 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
6PL non-polymer         . 
'(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 
1-PALMITOYL-2-STEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE 'C42 H85 N O8 P 1' 763.100 
ALA 'L-peptide linking' y ALANINE ?                                                  'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE ?                                                  'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                                                  'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                                                  'C4 H7 N O4'       133.103 
CYS 'L-peptide linking' y CYSTEINE ?                                                  'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                                                  'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                                                  'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE ?                                                  'C2 H5 N O2'       75.067  
HIS 'L-peptide linking' y HISTIDINE ?                                                  'C6 H10 N3 O2 1'   156.162 
ILE 'L-peptide linking' y ISOLEUCINE ?                                                  'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE ?                                                  'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE ?                                                  'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE ?                                                  'C5 H11 N O2 S'    149.211 
PHE 'L-peptide linking' y PHENYLALANINE ?                                                  'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE ?                                                  'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE ?                                                  'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE ?                                                  'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                                                  'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE ?                                                  'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE ?                                                  'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   SER 2   2   ?   ?   ?   A . n 
A 1 3   THR 3   3   ?   ?   ?   A . n 
A 1 4   ILE 4   4   ?   ?   ?   A . n 
A 1 5   LYS 5   5   ?   ?   ?   A . n 
A 1 6   PRO 6   6   ?   ?   ?   A . n 
A 1 7   SER 7   7   ?   ?   ?   A . n 
A 1 8   PRO 8   8   ?   ?   ?   A . n 
A 1 9   SER 9   9   ?   ?   ?   A . n 
A 1 10  ASN 10  10  ?   ?   ?   A . n 
A 1 11  ASN 11  11  ?   ?   ?   A . n 
A 1 12  ASN 12  12  ?   ?   ?   A . n 
A 1 13  LEU 13  13  ?   ?   ?   A . n 
A 1 14  LYS 14  14  ?   ?   ?   A . n 
A 1 15  VAL 15  15  ?   ?   ?   A . n 
A 1 16  ARG 16  16  ?   ?   ?   A . n 
A 1 17  SER 17  17  ?   ?   ?   A . n 
A 1 18  ARG 18  18  ?   ?   ?   A . n 
A 1 19  PRO 19  19  ?   ?   ?   A . n 
A 1 20  ARG 20  20  ?   ?   ?   A . n 
A 1 21  ARG 21  21  ?   ?   ?   A . n 
A 1 22  LYS 22  22  ?   ?   ?   A . n 
A 1 23  SER 23  23  ?   ?   ?   A . n 
A 1 24  SER 24  24  ?   ?   ?   A . n 
A 1 25  ILE 25  25  ?   ?   ?   A . n 
A 1 26  GLY 26  26  ?   ?   ?   A . n 
A 1 27  LYS 27  27  ?   ?   ?   A . n 
A 1 28  ILE 28  28  ?   ?   ?   A . n 
A 1 29  ASP 29  29  ?   ?   ?   A . n 
A 1 30  LEU 30  30  ?   ?   ?   A . n 
A 1 31  GLY 31  31  ?   ?   ?   A . n 
A 1 32  ASP 32  32  ?   ?   ?   A . n 
A 1 33  THR 33  33  ?   ?   ?   A . n 
A 1 34  VAL 34  34  ?   ?   ?   A . n 
A 1 35  PRO 35  35  ?   ?   ?   A . n 
A 1 36  SER 36  36  ?   ?   ?   A . n 
A 1 37  LEU 37  37  ?   ?   ?   A . n 
A 1 38  GLY 38  38  ?   ?   ?   A . n 
A 1 39  THR 39  39  ?   ?   ?   A . n 
A 1 40  MET 40  40  ?   ?   ?   A . n 
A 1 41  PHE 41  41  ?   ?   ?   A . n 
A 1 42  GLU 42  42  ?   ?   ?   A . n 
A 1 43  THR 43  43  ?   ?   ?   A . n 
A 1 44  LYS 44  44  ?   ?   ?   A . n 
A 1 45  GLU 45  45  ?   ?   ?   A . n 
A 1 46  SER 46  46  ?   ?   ?   A . n 
A 1 47  LYS 47  47  ?   ?   ?   A . n 
A 1 48  THR 48  48  ?   ?   ?   A . n 
A 1 49  ALA 49  49  ?   ?   ?   A . n 
A 1 50  ALA 50  50  ?   ?   ?   A . n 
A 1 51  LYS 51  51  ?   ?   ?   A . n 
A 1 52  ARG 52  52  ?   ?   ?   A . n 
A 1 53  ARG 53  53  ?   ?   ?   A . n 
A 1 54  MET 54  54  ?   ?   ?   A . n 
A 1 55  GLN 55  55  ?   ?   ?   A . n 
A 1 56  ARG 56  56  ?   ?   ?   A . n 
A 1 57  LEU 57  57  ?   ?   ?   A . n 
A 1 58  SER 58  58  ?   ?   ?   A . n 
A 1 59  GLU 59  59  ?   ?   ?   A . n 
A 1 60  ALA 60  60  ?   ?   ?   A . n 
A 1 61  THR 61  61  ?   ?   ?   A . n 
A 1 62  LYS 62  62  ?   ?   ?   A . n 
A 1 63  ASN 63  63  ?   ?   ?   A . n 
A 1 64  ASP 64  64  ?   ?   ?   A . n 
A 1 65  SER 65  65  ?   ?   ?   A . n 
A 1 66  ASP 66  66  ?   ?   ?   A . n 
A 1 67  LEU 67  67  ?   ?   ?   A . n 
A 1 68  VAL 68  68  ?   ?   ?   A . n 
A 1 69  LYS 69  69  ?   ?   ?   A . n 
A 1 70  LYS 70  70  ?   ?   ?   A . n 
A 1 71  ILE 71  71  71  ILE ILE A . n 
A 1 72  TRP 72  72  72  TRP TRP A . n 
A 1 73  PHE 73  73  73  PHE PHE A . n 
A 1 74  SER 74  74  74  SER SER A . n 
A 1 75  PHE 75  75  75  PHE PHE A . n 
A 1 76  ARG 76  76  76  ARG ARG A . n 
A 1 77  GLU 77  77  77  GLU GLU A . n 
A 1 78  ILE 78  78  78  ILE ILE A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  TYR 80  80  80  TYR TYR A . n 
A 1 81  ARG 81  81  81  ARG ARG A . n 
A 1 82  HIS 82  82  82  HIS HIS A . n 
A 1 83  ALA 83  83  83  ALA ALA A . n 
A 1 84  TRP 84  84  84  TRP TRP A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  ALA 86  86  86  ALA ALA A . n 
A 1 87  PRO 87  87  87  PRO PRO A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  MET 89  89  89  MET MET A . n 
A 1 90  ILE 90  90  90  ILE ILE A . n 
A 1 91  LEU 91  91  91  LEU LEU A . n 
A 1 92  ILE 92  92  92  ILE ILE A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  VAL 94  94  94  VAL VAL A . n 
A 1 95  TYR 95  95  95  TYR TYR A . n 
A 1 96  SER 96  96  96  SER SER A . n 
A 1 97  ALA 97  97  97  ALA ALA A . n 
A 1 98  TYR 98  98  98  TYR TYR A . n 
A 1 99  PHE 99  99  99  PHE PHE A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 SER 101 101 101 SER SER A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 ASN 103 103 103 ASN ASN A . n 
A 1 104 THR 104 104 104 THR THR A . n 
A 1 105 THR 105 105 105 THR THR A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 THR 107 107 107 THR THR A . n 
A 1 108 ASN 108 108 108 ASN ASN A . n 
A 1 109 VAL 109 109 109 VAL VAL A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 HIS 111 111 111 HIS HIS A . n 
A 1 112 ARG 112 112 112 ARG ARG A . n 
A 1 113 PHE 113 113 113 PHE PHE A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 VAL 116 116 116 VAL VAL A . n 
A 1 117 SER 117 117 117 SER SER A . n 
A 1 118 TYR 118 118 118 TYR TYR A . n 
A 1 119 GLN 119 119 119 GLN GLN A . n 
A 1 120 ILE 120 120 120 ILE ILE A . n 
A 1 121 GLY 121 121 121 GLY GLY A . n 
A 1 122 ASP 122 122 122 ASP ASP A . n 
A 1 123 THR 123 123 123 THR THR A . n 
A 1 124 ASN 124 124 124 ASN ASN A . n 
A 1 125 ALA 125 125 125 ALA ALA A . n 
A 1 126 TYR 126 126 126 TYR TYR A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 LYS 128 128 128 LYS LYS A . n 
A 1 129 GLY 129 129 129 GLY GLY A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 ASN 131 131 131 ASN ASN A . n 
A 1 132 ASP 132 132 132 ASP ASP A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 CYS 134 134 134 CYS CYS A . n 
A 1 135 PHE 135 135 135 PHE PHE A . n 
A 1 136 VAL 136 136 136 VAL VAL A . n 
A 1 137 PHE 137 137 137 PHE PHE A . n 
A 1 138 TYR 138 138 138 TYR TYR A . n 
A 1 139 TYR 139 139 139 TYR TYR A . n 
A 1 140 MET 140 140 140 MET MET A . n 
A 1 141 ILE 141 141 141 ILE ILE A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 PHE 143 143 143 PHE PHE A . n 
A 1 144 THR 144 144 144 THR THR A . n 
A 1 145 PHE 145 145 145 PHE PHE A . n 
A 1 146 LEU 146 146 146 LEU LEU A . n 
A 1 147 ARG 147 147 147 ARG ARG A . n 
A 1 148 GLU 148 148 148 GLU GLU A . n 
A 1 149 PHE 149 149 149 PHE PHE A . n 
A 1 150 LEU 150 150 150 LEU LEU A . n 
A 1 151 MET 151 151 151 MET MET A . n 
A 1 152 ASP 152 152 152 ASP ASP A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 VAL 154 154 154 VAL VAL A . n 
A 1 155 ILE 155 155 155 ILE ILE A . n 
A 1 156 ARG 156 156 156 ARG ARG A . n 
A 1 157 PRO 157 157 157 PRO PRO A . n 
A 1 158 PHE 158 158 158 PHE PHE A . n 
A 1 159 ALA 159 159 159 ALA ALA A . n 
A 1 160 ILE 160 160 160 ILE ILE A . n 
A 1 161 ARG 161 161 161 ARG ARG A . n 
A 1 162 LEU 162 162 162 LEU LEU A . n 
A 1 163 HIS 163 163 163 HIS HIS A . n 
A 1 164 VAL 164 164 164 VAL VAL A . n 
A 1 165 THR 165 165 165 THR THR A . n 
A 1 166 SER 166 166 166 SER SER A . n 
A 1 167 LYS 167 167 167 LYS LYS A . n 
A 1 168 HIS 168 168 168 HIS HIS A . n 
A 1 169 ARG 169 169 169 ARG ARG A . n 
A 1 170 ILE 170 170 170 ILE ILE A . n 
A 1 171 LYS 171 171 171 LYS LYS A . n 
A 1 172 ARG 172 172 172 ARG ARG A . n 
A 1 173 ILE 173 173 173 ILE ILE A . n 
A 1 174 MET 174 174 174 MET MET A . n 
A 1 175 GLU 175 175 175 GLU GLU A . n 
A 1 176 GLN 176 176 176 GLN GLN A . n 
A 1 177 MET 177 177 177 MET MET A . n 
A 1 178 TYR 178 178 178 TYR TYR A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 ILE 180 180 180 ILE ILE A . n 
A 1 181 PHE 181 181 181 PHE PHE A . n 
A 1 182 TYR 182 182 182 TYR TYR A . n 
A 1 183 THR 183 183 183 THR THR A . n 
A 1 184 GLY 184 184 184 GLY GLY A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 SER 186 186 186 SER SER A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 PRO 188 188 188 PRO PRO A . n 
A 1 189 PHE 189 189 189 PHE PHE A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 ILE 191 191 191 ILE ILE A . n 
A 1 192 TYR 192 192 192 TYR TYR A . n 
A 1 193 CYS 193 193 193 CYS CYS A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 TYR 195 195 195 TYR TYR A . n 
A 1 196 HIS 196 196 196 HIS HIS A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 ASP 198 198 198 ASP ASP A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 TRP 200 200 200 TRP TRP A . n 
A 1 201 PHE 201 201 201 PHE PHE A . n 
A 1 202 PHE 202 202 202 PHE PHE A . n 
A 1 203 ASN 203 203 203 ASN ASN A . n 
A 1 204 THR 204 204 204 THR THR A . n 
A 1 205 LYS 205 205 205 LYS LYS A . n 
A 1 206 ALA 206 206 206 ALA ALA A . n 
A 1 207 MET 207 207 207 MET MET A . n 
A 1 208 TYR 208 208 208 TYR TYR A . n 
A 1 209 ARG 209 209 209 ARG ARG A . n 
A 1 210 THR 210 210 210 THR THR A . n 
A 1 211 TYR 211 211 211 TYR TYR A . n 
A 1 212 PRO 212 212 212 PRO PRO A . n 
A 1 213 ASP 213 213 213 ASP ASP A . n 
A 1 214 PHE 214 214 214 PHE PHE A . n 
A 1 215 THR 215 215 215 THR THR A . n 
A 1 216 ASN 216 216 216 ASN ASN A . n 
A 1 217 PRO 217 217 217 PRO PRO A . n 
A 1 218 PHE 218 218 218 PHE PHE A . n 
A 1 219 LEU 219 219 219 LEU LEU A . n 
A 1 220 PHE 220 220 220 PHE PHE A . n 
A 1 221 LYS 221 221 221 LYS LYS A . n 
A 1 222 VAL 222 222 222 VAL VAL A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 TYR 224 224 224 TYR TYR A . n 
A 1 225 LEU 225 225 225 LEU LEU A . n 
A 1 226 GLY 226 226 226 GLY GLY A . n 
A 1 227 GLN 227 227 227 GLN GLN A . n 
A 1 228 ALA 228 228 228 ALA ALA A . n 
A 1 229 ALA 229 229 229 ALA ALA A . n 
A 1 230 PHE 230 230 230 PHE PHE A . n 
A 1 231 TRP 231 231 231 TRP TRP A . n 
A 1 232 ALA 232 232 232 ALA ALA A . n 
A 1 233 GLN 233 233 233 GLN GLN A . n 
A 1 234 GLN 234 234 234 GLN GLN A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 CYS 236 236 236 CYS CYS A . n 
A 1 237 ILE 237 237 237 ILE ILE A . n 
A 1 238 LEU 238 238 238 LEU LEU A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 GLN 241 241 241 GLN GLN A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 GLU 243 243 243 GLU GLU A . n 
A 1 244 LYS 244 244 244 LYS LYS A . n 
A 1 245 PRO 245 245 245 PRO PRO A . n 
A 1 246 ARG 246 246 246 ARG ARG A . n 
A 1 247 LYS 247 247 247 LYS LYS A . n 
A 1 248 ASP 248 248 248 ASP ASP A . n 
A 1 249 HIS 249 249 249 HIS HIS A . n 
A 1 250 ASN 250 250 250 ASN ASN A . n 
A 1 251 GLU 251 251 251 GLU GLU A . n 
A 1 252 LEU 252 252 252 LEU LEU A . n 
A 1 253 THR 253 253 253 THR THR A . n 
A 1 254 PHE 254 254 254 PHE PHE A . n 
A 1 255 HIS 255 255 255 HIS HIS A . n 
A 1 256 HIS 256 256 256 HIS HIS A . n 
A 1 257 ILE 257 257 257 ILE ILE A . n 
A 1 258 VAL 258 258 258 VAL VAL A . n 
A 1 259 THR 259 259 259 THR THR A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 ILE 263 263 263 ILE ILE A . n 
A 1 264 TRP 264 264 264 TRP TRP A . n 
A 1 265 SER 265 265 265 SER SER A . n 
A 1 266 SER 266 266 266 SER SER A . n 
A 1 267 TYR 267 267 267 TYR TYR A . n 
A 1 268 VAL 268 268 268 VAL VAL A . n 
A 1 269 PHE 269 269 269 PHE PHE A . n 
A 1 270 HIS 270 270 270 HIS HIS A . n 
A 1 271 PHE 271 271 271 PHE PHE A . n 
A 1 272 THR 272 272 272 THR THR A . n 
A 1 273 LYS 273 273 273 LYS LYS A . n 
A 1 274 MET 274 274 274 MET MET A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 LEU 276 276 276 LEU LEU A . n 
A 1 277 PRO 277 277 277 PRO PRO A . n 
A 1 278 ILE 278 278 278 ILE ILE A . n 
A 1 279 TYR 279 279 279 TYR TYR A . n 
A 1 280 ILE 280 280 280 ILE ILE A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 MET 282 282 282 MET MET A . n 
A 1 283 ASP 283 283 283 ASP ASP A . n 
A 1 284 VAL 284 284 284 VAL VAL A . n 
A 1 285 SER 285 285 285 SER SER A . n 
A 1 286 ASP 286 286 286 ASP ASP A . n 
A 1 287 PHE 287 287 287 PHE PHE A . n 
A 1 288 LEU 288 288 288 LEU LEU A . n 
A 1 289 LEU 289 289 289 LEU LEU A . n 
A 1 290 SER 290 290 290 SER SER A . n 
A 1 291 PHE 291 291 291 PHE PHE A . n 
A 1 292 SER 292 292 292 SER SER A . n 
A 1 293 LYS 293 293 293 LYS LYS A . n 
A 1 294 THR 294 294 294 THR THR A . n 
A 1 295 LEU 295 295 295 LEU LEU A . n 
A 1 296 ASN 296 296 296 ASN ASN A . n 
A 1 297 TYR 297 297 297 TYR TYR A . n 
A 1 298 LEU 298 298 298 LEU LEU A . n 
A 1 299 ASP 299 299 299 ASP ASP A . n 
A 1 300 SER 300 300 300 SER SER A . n 
A 1 301 GLY 301 301 301 GLY GLY A . n 
A 1 302 LEU 302 302 302 LEU LEU A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 PHE 304 304 304 PHE PHE A . n 
A 1 305 PHE 305 305 305 PHE PHE A . n 
A 1 306 SER 306 306 306 SER SER A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 ILE 309 309 309 ILE ILE A . n 
A 1 310 PHE 310 310 310 PHE PHE A . n 
A 1 311 VAL 311 311 311 VAL VAL A . n 
A 1 312 VAL 312 312 312 VAL VAL A . n 
A 1 313 ALA 313 313 313 ALA ALA A . n 
A 1 314 TRP 314 314 314 TRP TRP A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 TYR 316 316 316 TYR TYR A . n 
A 1 317 LEU 317 317 317 LEU LEU A . n 
A 1 318 ARG 318 318 318 ARG ARG A . n 
A 1 319 HIS 319 319 319 HIS HIS A . n 
A 1 320 TYR 320 320 320 TYR TYR A . n 
A 1 321 ILE 321 321 321 ILE ILE A . n 
A 1 322 ASN 322 322 322 ASN ASN A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 LYS 324 324 324 LYS LYS A . n 
A 1 325 ILE 325 325 325 ILE ILE A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 TRP 327 327 327 TRP TRP A . n 
A 1 328 SER 328 328 328 SER SER A . n 
A 1 329 VAL 329 329 329 VAL VAL A . n 
A 1 330 LEU 330 330 330 LEU LEU A . n 
A 1 331 THR 331 331 331 THR THR A . n 
A 1 332 GLN 332 332 332 GLN GLN A . n 
A 1 333 PHE 333 333 333 PHE PHE A . n 
A 1 334 ARG 334 334 334 ARG ARG A . n 
A 1 335 THR 335 335 335 THR THR A . n 
A 1 336 GLU 336 336 336 GLU GLU A . n 
A 1 337 GLY 337 337 337 GLY GLY A . n 
A 1 338 ASN 338 338 338 ASN ASN A . n 
A 1 339 TYR 339 339 339 TYR TYR A . n 
A 1 340 VAL 340 340 340 VAL VAL A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 ASN 342 342 342 ASN ASN A . n 
A 1 343 PHE 343 343 343 PHE PHE A . n 
A 1 344 ALA 344 344 344 ALA ALA A . n 
A 1 345 THR 345 345 345 THR THR A . n 
A 1 346 GLN 346 346 346 GLN GLN A . n 
A 1 347 GLN 347 347 347 GLN GLN A . n 
A 1 348 TYR 348 348 348 TYR TYR A . n 
A 1 349 LYS 349 349 349 LYS LYS A . n 
A 1 350 CYS 350 350 350 CYS CYS A . n 
A 1 351 TRP 351 351 351 TRP TRP A . n 
A 1 352 ILE 352 352 352 ILE ILE A . n 
A 1 353 SER 353 353 353 SER SER A . n 
A 1 354 LEU 354 354 354 LEU LEU A . n 
A 1 355 PRO 355 355 355 PRO PRO A . n 
A 1 356 ILE 356 356 356 ILE ILE A . n 
A 1 357 VAL 357 357 357 VAL VAL A . n 
A 1 358 PHE 358 358 358 PHE PHE A . n 
A 1 359 VAL 359 359 359 VAL VAL A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 ILE 361 361 361 ILE ILE A . n 
A 1 362 GLY 362 362 362 GLY GLY A . n 
A 1 363 ALA 363 363 363 ALA ALA A . n 
A 1 364 LEU 364 364 364 LEU LEU A . n 
A 1 365 GLN 365 365 365 GLN GLN A . n 
A 1 366 LEU 366 366 366 LEU LEU A . n 
A 1 367 VAL 367 367 367 VAL VAL A . n 
A 1 368 ASN 368 368 368 ASN ASN A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 TYR 370 370 370 TYR TYR A . n 
A 1 371 TRP 371 371 371 TRP TRP A . n 
A 1 372 LEU 372 372 372 LEU LEU A . n 
A 1 373 PHE 373 373 373 PHE PHE A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 ILE 375 375 375 ILE ILE A . n 
A 1 376 PHE 376 376 376 PHE PHE A . n 
A 1 377 ARG 377 377 377 ARG ARG A . n 
A 1 378 VAL 378 378 378 VAL VAL A . n 
A 1 379 LEU 379 379 379 LEU LEU A . n 
A 1 380 TYR 380 380 380 TYR TYR A . n 
A 1 381 ARG 381 381 381 ARG ARG A . n 
A 1 382 ILE 382 382 382 ILE ILE A . n 
A 1 383 LEU 383 383 383 LEU LEU A . n 
A 1 384 TRP 384 384 384 TRP TRP A . n 
A 1 385 ARG 385 385 385 ARG ARG A . n 
A 1 386 GLY 386 386 ?   ?   ?   A . n 
A 1 387 ILE 387 387 ?   ?   ?   A . n 
A 1 388 LEU 388 388 ?   ?   ?   A . n 
A 1 389 LYS 389 389 ?   ?   ?   A . n 
A 1 390 ASP 390 390 ?   ?   ?   A . n 
A 1 391 ASP 391 391 ?   ?   ?   A . n 
A 1 392 ARG 392 392 ?   ?   ?   A . n 
A 1 393 SER 393 393 ?   ?   ?   A . n 
A 1 394 ASP 394 394 ?   ?   ?   A . n 
A 1 395 SER 395 395 ?   ?   ?   A . n 
A 1 396 GLU 396 396 ?   ?   ?   A . n 
A 1 397 SER 397 397 ?   ?   ?   A . n 
A 1 398 ASP 398 398 ?   ?   ?   A . n 
A 1 399 GLU 399 399 ?   ?   ?   A . n 
A 1 400 GLU 400 400 ?   ?   ?   A . n 
A 1 401 SER 401 401 ?   ?   ?   A . n 
A 1 402 ASP 402 402 ?   ?   ?   A . n 
A 1 403 GLU 403 403 ?   ?   ?   A . n 
A 1 404 SER 404 404 ?   ?   ?   A . n 
A 1 405 SER 405 405 ?   ?   ?   A . n 
A 1 406 THR 406 406 ?   ?   ?   A . n 
A 1 407 THR 407 407 ?   ?   ?   A . n 
A 1 408 PRO 408 408 ?   ?   ?   A . n 
A 1 409 THR 409 409 ?   ?   ?   A . n 
A 1 410 ASP 410 410 ?   ?   ?   A . n 
A 1 411 SER 411 411 ?   ?   ?   A . n 
A 1 412 THR 412 412 ?   ?   ?   A . n 
A 1 413 PRO 413 413 ?   ?   ?   A . n 
A 1 414 THR 414 414 ?   ?   ?   A . n 
A 1 415 LYS 415 415 ?   ?   ?   A . n 
A 1 416 LYS 416 416 ?   ?   ?   A . n 
A 1 417 ASP 417 417 ?   ?   ?   A . n 
A 1 418 ILE 418 418 ?   ?   ?   A . n 
A 1 419 LEU 419 419 ?   ?   ?   A . n 
A 1 420 GLU 420 420 ?   ?   ?   A . n 
A 1 421 ASP 421 421 ?   ?   ?   A . n 
A 1 422 TYR 422 422 ?   ?   ?   A . n 
A 1 423 LYS 423 423 ?   ?   ?   A . n 
A 1 424 ASP 424 424 ?   ?   ?   A . n 
A 1 425 ASP 425 425 ?   ?   ?   A . n 
A 1 426 ASP 426 426 ?   ?   ?   A . n 
A 1 427 ASP 427 427 ?   ?   ?   A . n 
A 1 428 LYS 428 428 ?   ?   ?   A . n 
B 2 1   MET 1   1   ?   ?   ?   B . n 
B 2 2   SER 2   2   ?   ?   ?   B . n 
B 2 3   GLN 3   3   ?   ?   ?   B . n 
B 2 4   PRO 4   4   ?   ?   ?   B . n 
B 2 5   THR 5   5   ?   ?   ?   B . n 
B 2 6   PRO 6   6   ?   ?   ?   B . n 
B 2 7   ILE 7   7   ?   ?   ?   B . n 
B 2 8   ILE 8   8   ?   ?   ?   B . n 
B 2 9   THR 9   9   ?   ?   ?   B . n 
B 2 10  THR 10  10  ?   ?   ?   B . n 
B 2 11  LYS 11  11  ?   ?   ?   B . n 
B 2 12  SER 12  12  ?   ?   ?   B . n 
B 2 13  ALA 13  13  ?   ?   ?   B . n 
B 2 14  ALA 14  14  ?   ?   ?   B . n 
B 2 15  LYS 15  15  ?   ?   ?   B . n 
B 2 16  PRO 16  16  ?   ?   ?   B . n 
B 2 17  LYS 17  17  ?   ?   ?   B . n 
B 2 18  PRO 18  18  18  PRO PRO B . n 
B 2 19  LYS 19  19  19  LYS LYS B . n 
B 2 20  ILE 20  20  20  ILE ILE B . n 
B 2 21  PHE 21  21  21  PHE PHE B . n 
B 2 22  ASN 22  22  22  ASN ASN B . n 
B 2 23  LEU 23  23  23  LEU LEU B . n 
B 2 24  PHE 24  24  24  PHE PHE B . n 
B 2 25  ARG 25  25  25  ARG ARG B . n 
B 2 26  VAL 26  26  26  VAL VAL B . n 
B 2 27  CYS 27  27  27  CYS CYS B . n 
B 2 28  PHE 28  28  28  PHE PHE B . n 
B 2 29  ILE 29  29  29  ILE ILE B . n 
B 2 30  SER 30  30  30  SER SER B . n 
B 2 31  LEU 31  31  31  LEU LEU B . n 
B 2 32  LEU 32  32  32  LEU LEU B . n 
B 2 33  LEU 33  33  33  LEU LEU B . n 
B 2 34  ILE 34  34  34  ILE ILE B . n 
B 2 35  ALA 35  35  35  ALA ALA B . n 
B 2 36  ALA 36  36  36  ALA ALA B . n 
B 2 37  VAL 37  37  37  VAL VAL B . n 
B 2 38  GLU 38  38  38  GLU GLU B . n 
B 2 39  TYR 39  39  39  TYR TYR B . n 
B 2 40  PHE 40  40  40  PHE PHE B . n 
B 2 41  LYS 41  41  41  LYS LYS B . n 
B 2 42  TYR 42  42  42  TYR TYR B . n 
B 2 43  GLY 43  43  43  GLY GLY B . n 
B 2 44  THR 44  44  44  THR THR B . n 
B 2 45  ARG 45  45  45  ARG ARG B . n 
B 2 46  ILE 46  46  46  ILE ILE B . n 
B 2 47  ASN 47  47  47  ASN ASN B . n 
B 2 48  TYR 48  48  48  TYR TYR B . n 
B 2 49  GLU 49  49  49  GLU GLU B . n 
B 2 50  TRP 50  50  50  TRP TRP B . n 
B 2 51  PHE 51  51  51  PHE PHE B . n 
B 2 52  HIS 52  52  52  HIS HIS B . n 
B 2 53  CYS 53  53  53  CYS CYS B . n 
B 2 54  THR 54  54  54  THR THR B . n 
B 2 55  PRO 55  55  55  PRO PRO B . n 
B 2 56  ILE 56  56  56  ILE ILE B . n 
B 2 57  LYS 57  57  57  LYS LYS B . n 
B 2 58  GLU 58  58  58  GLU GLU B . n 
B 2 59  PRO 59  59  59  PRO PRO B . n 
B 2 60  GLN 60  60  60  GLN GLN B . n 
B 2 61  SER 61  61  61  SER SER B . n 
B 2 62  GLY 62  62  62  GLY GLY B . n 
B 2 63  SER 63  63  63  SER SER B . n 
B 2 64  VAL 64  64  64  VAL VAL B . n 
B 2 65  ILE 65  65  65  ILE ILE B . n 
B 2 66  LYS 66  66  66  LYS LYS B . n 
B 2 67  LEU 67  67  67  LEU LEU B . n 
B 2 68  TRP 68  68  68  TRP TRP B . n 
B 2 69  ALA 69  69  69  ALA ALA B . n 
B 2 70  ARG 70  70  70  ARG ARG B . n 
B 2 71  GLY 71  71  71  GLY GLY B . n 
B 2 72  GLY 72  72  72  GLY GLY B . n 
B 2 73  PRO 73  73  73  PRO PRO B . n 
B 2 74  SER 74  74  74  SER SER B . n 
B 2 75  CYS 75  75  75  CYS CYS B . n 
B 2 76  ASP 76  76  76  ASP ASP B . n 
B 2 77  LYS 77  77  77  LYS LYS B . n 
B 2 78  ARG 78  78  78  ARG ARG B . n 
B 2 79  GLY 79  79  79  GLY GLY B . n 
B 2 80  GLU 80  80  80  GLU GLU B . n 
B 2 81  TYR 81  81  81  TYR TYR B . n 
B 2 82  LYS 82  82  82  LYS LYS B . n 
B 2 83  THR 83  83  83  THR THR B . n 
B 2 84  ILE 84  84  84  ILE ILE B . n 
B 2 85  VAL 85  85  85  VAL VAL B . n 
B 2 86  LYS 86  86  86  LYS LYS B . n 
B 2 87  ARG 87  87  87  ARG ARG B . n 
B 2 88  ILE 88  88  88  ILE ILE B . n 
B 2 89  THR 89  89  89  THR THR B . n 
B 2 90  ARG 90  90  90  ARG ARG B . n 
B 2 91  ASP 91  91  91  ASP ASP B . n 
B 2 92  TYR 92  92  92  TYR TYR B . n 
B 2 93  GLU 93  93  93  GLU GLU B . n 
B 2 94  PRO 94  94  94  PRO PRO B . n 
B 2 95  ASN 95  95  95  ASN ASN B . n 
B 2 96  ASP 96  96  96  ASP ASP B . n 
B 2 97  GLU 97  97  97  GLU GLU B . n 
B 2 98  HIS 98  98  98  HIS HIS B . n 
B 2 99  LEU 99  99  99  LEU LEU B . n 
B 2 100 SER 100 100 100 SER SER B . n 
B 2 101 PHE 101 101 101 PHE PHE B . n 
B 2 102 CYS 102 102 102 CYS CYS B . n 
B 2 103 ILE 103 103 103 ILE ILE B . n 
B 2 104 ILE 104 104 104 ILE ILE B . n 
B 2 105 GLU 105 105 105 GLU GLU B . n 
B 2 106 ASN 106 106 106 ASN ASN B . n 
B 2 107 ASP 107 107 107 ASP ASP B . n 
B 2 108 ASN 108 108 108 ASN ASN B . n 
B 2 109 VAL 109 109 109 VAL VAL B . n 
B 2 110 PRO 110 110 110 PRO PRO B . n 
B 2 111 PRO 111 111 111 PRO PRO B . n 
B 2 112 VAL 112 112 112 VAL VAL B . n 
B 2 113 HIS 113 113 113 HIS HIS B . n 
B 2 114 TYR 114 114 114 TYR TYR B . n 
B 2 115 PRO 115 115 115 PRO PRO B . n 
B 2 116 ILE 116 116 116 ILE ILE B . n 
B 2 117 HIS 117 117 117 HIS HIS B . n 
B 2 118 GLU 118 118 118 GLU GLU B . n 
B 2 119 ASP 119 119 119 ASP ASP B . n 
B 2 120 LYS 120 120 120 LYS LYS B . n 
B 2 121 GLY 121 121 121 GLY GLY B . n 
B 2 122 GLU 122 122 122 GLU GLU B . n 
B 2 123 PRO 123 123 123 PRO PRO B . n 
B 2 124 GLY 124 124 124 GLY GLY B . n 
B 2 125 TYR 125 125 125 TYR TYR B . n 
B 2 126 VAL 126 126 126 VAL VAL B . n 
B 2 127 ALA 127 127 127 ALA ALA B . n 
B 2 128 TYR 128 128 128 TYR TYR B . n 
B 2 129 VAL 129 129 129 VAL VAL B . n 
B 2 130 GLY 130 130 130 GLY GLY B . n 
B 2 131 TYR 131 131 131 TYR TYR B . n 
B 2 132 ASP 132 132 132 ASP ASP B . n 
B 2 133 THR 133 133 133 THR THR B . n 
B 2 134 ASP 134 134 134 ASP ASP B . n 
B 2 135 SER 135 135 135 SER SER B . n 
B 2 136 GLU 136 136 136 GLU GLU B . n 
B 2 137 LEU 137 137 137 LEU LEU B . n 
B 2 138 VAL 138 138 138 VAL VAL B . n 
B 2 139 GLN 139 139 139 GLN GLN B . n 
B 2 140 GLU 140 140 140 GLU GLU B . n 
B 2 141 LEU 141 141 141 LEU LEU B . n 
B 2 142 CYS 142 142 142 CYS CYS B . n 
B 2 143 ALA 143 143 143 ALA ALA B . n 
B 2 144 ASP 144 144 144 ASP ASP B . n 
B 2 145 SER 145 145 145 SER SER B . n 
B 2 146 THR 146 146 146 THR THR B . n 
B 2 147 ILE 147 147 147 ILE ILE B . n 
B 2 148 TYR 148 148 148 TYR TYR B . n 
B 2 149 HIS 149 149 149 HIS HIS B . n 
B 2 150 MET 150 150 150 MET MET B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   SER 2   2   ?   ?   ?   C . n 
C 1 3   THR 3   3   ?   ?   ?   C . n 
C 1 4   ILE 4   4   ?   ?   ?   C . n 
C 1 5   LYS 5   5   ?   ?   ?   C . n 
C 1 6   PRO 6   6   ?   ?   ?   C . n 
C 1 7   SER 7   7   ?   ?   ?   C . n 
C 1 8   PRO 8   8   ?   ?   ?   C . n 
C 1 9   SER 9   9   ?   ?   ?   C . n 
C 1 10  ASN 10  10  ?   ?   ?   C . n 
C 1 11  ASN 11  11  ?   ?   ?   C . n 
C 1 12  ASN 12  12  ?   ?   ?   C . n 
C 1 13  LEU 13  13  ?   ?   ?   C . n 
C 1 14  LYS 14  14  ?   ?   ?   C . n 
C 1 15  VAL 15  15  ?   ?   ?   C . n 
C 1 16  ARG 16  16  ?   ?   ?   C . n 
C 1 17  SER 17  17  ?   ?   ?   C . n 
C 1 18  ARG 18  18  ?   ?   ?   C . n 
C 1 19  PRO 19  19  ?   ?   ?   C . n 
C 1 20  ARG 20  20  ?   ?   ?   C . n 
C 1 21  ARG 21  21  ?   ?   ?   C . n 
C 1 22  LYS 22  22  ?   ?   ?   C . n 
C 1 23  SER 23  23  ?   ?   ?   C . n 
C 1 24  SER 24  24  ?   ?   ?   C . n 
C 1 25  ILE 25  25  ?   ?   ?   C . n 
C 1 26  GLY 26  26  ?   ?   ?   C . n 
C 1 27  LYS 27  27  ?   ?   ?   C . n 
C 1 28  ILE 28  28  ?   ?   ?   C . n 
C 1 29  ASP 29  29  ?   ?   ?   C . n 
C 1 30  LEU 30  30  ?   ?   ?   C . n 
C 1 31  GLY 31  31  ?   ?   ?   C . n 
C 1 32  ASP 32  32  ?   ?   ?   C . n 
C 1 33  THR 33  33  ?   ?   ?   C . n 
C 1 34  VAL 34  34  ?   ?   ?   C . n 
C 1 35  PRO 35  35  ?   ?   ?   C . n 
C 1 36  SER 36  36  ?   ?   ?   C . n 
C 1 37  LEU 37  37  ?   ?   ?   C . n 
C 1 38  GLY 38  38  ?   ?   ?   C . n 
C 1 39  THR 39  39  ?   ?   ?   C . n 
C 1 40  MET 40  40  ?   ?   ?   C . n 
C 1 41  PHE 41  41  ?   ?   ?   C . n 
C 1 42  GLU 42  42  ?   ?   ?   C . n 
C 1 43  THR 43  43  ?   ?   ?   C . n 
C 1 44  LYS 44  44  ?   ?   ?   C . n 
C 1 45  GLU 45  45  ?   ?   ?   C . n 
C 1 46  SER 46  46  ?   ?   ?   C . n 
C 1 47  LYS 47  47  ?   ?   ?   C . n 
C 1 48  THR 48  48  ?   ?   ?   C . n 
C 1 49  ALA 49  49  ?   ?   ?   C . n 
C 1 50  ALA 50  50  ?   ?   ?   C . n 
C 1 51  LYS 51  51  ?   ?   ?   C . n 
C 1 52  ARG 52  52  ?   ?   ?   C . n 
C 1 53  ARG 53  53  ?   ?   ?   C . n 
C 1 54  MET 54  54  ?   ?   ?   C . n 
C 1 55  GLN 55  55  ?   ?   ?   C . n 
C 1 56  ARG 56  56  ?   ?   ?   C . n 
C 1 57  LEU 57  57  ?   ?   ?   C . n 
C 1 58  SER 58  58  ?   ?   ?   C . n 
C 1 59  GLU 59  59  ?   ?   ?   C . n 
C 1 60  ALA 60  60  ?   ?   ?   C . n 
C 1 61  THR 61  61  ?   ?   ?   C . n 
C 1 62  LYS 62  62  ?   ?   ?   C . n 
C 1 63  ASN 63  63  ?   ?   ?   C . n 
C 1 64  ASP 64  64  ?   ?   ?   C . n 
C 1 65  SER 65  65  ?   ?   ?   C . n 
C 1 66  ASP 66  66  ?   ?   ?   C . n 
C 1 67  LEU 67  67  ?   ?   ?   C . n 
C 1 68  VAL 68  68  ?   ?   ?   C . n 
C 1 69  LYS 69  69  ?   ?   ?   C . n 
C 1 70  LYS 70  70  ?   ?   ?   C . n 
C 1 71  ILE 71  71  71  ILE ILE C . n 
C 1 72  TRP 72  72  72  TRP TRP C . n 
C 1 73  PHE 73  73  73  PHE PHE C . n 
C 1 74  SER 74  74  74  SER SER C . n 
C 1 75  PHE 75  75  75  PHE PHE C . n 
C 1 76  ARG 76  76  76  ARG ARG C . n 
C 1 77  GLU 77  77  77  GLU GLU C . n 
C 1 78  ILE 78  78  78  ILE ILE C . n 
C 1 79  SER 79  79  79  SER SER C . n 
C 1 80  TYR 80  80  80  TYR TYR C . n 
C 1 81  ARG 81  81  81  ARG ARG C . n 
C 1 82  HIS 82  82  82  HIS HIS C . n 
C 1 83  ALA 83  83  83  ALA ALA C . n 
C 1 84  TRP 84  84  84  TRP TRP C . n 
C 1 85  ILE 85  85  85  ILE ILE C . n 
C 1 86  ALA 86  86  86  ALA ALA C . n 
C 1 87  PRO 87  87  87  PRO PRO C . n 
C 1 88  LEU 88  88  88  LEU LEU C . n 
C 1 89  MET 89  89  89  MET MET C . n 
C 1 90  ILE 90  90  90  ILE ILE C . n 
C 1 91  LEU 91  91  91  LEU LEU C . n 
C 1 92  ILE 92  92  92  ILE ILE C . n 
C 1 93  ALA 93  93  93  ALA ALA C . n 
C 1 94  VAL 94  94  94  VAL VAL C . n 
C 1 95  TYR 95  95  95  TYR TYR C . n 
C 1 96  SER 96  96  96  SER SER C . n 
C 1 97  ALA 97  97  97  ALA ALA C . n 
C 1 98  TYR 98  98  98  TYR TYR C . n 
C 1 99  PHE 99  99  99  PHE PHE C . n 
C 1 100 THR 100 100 100 THR THR C . n 
C 1 101 SER 101 101 101 SER SER C . n 
C 1 102 GLY 102 102 102 GLY GLY C . n 
C 1 103 ASN 103 103 103 ASN ASN C . n 
C 1 104 THR 104 104 104 THR THR C . n 
C 1 105 THR 105 105 105 THR THR C . n 
C 1 106 LYS 106 106 106 LYS LYS C . n 
C 1 107 THR 107 107 107 THR THR C . n 
C 1 108 ASN 108 108 108 ASN ASN C . n 
C 1 109 VAL 109 109 109 VAL VAL C . n 
C 1 110 LEU 110 110 110 LEU LEU C . n 
C 1 111 HIS 111 111 111 HIS HIS C . n 
C 1 112 ARG 112 112 112 ARG ARG C . n 
C 1 113 PHE 113 113 113 PHE PHE C . n 
C 1 114 VAL 114 114 114 VAL VAL C . n 
C 1 115 ALA 115 115 115 ALA ALA C . n 
C 1 116 VAL 116 116 116 VAL VAL C . n 
C 1 117 SER 117 117 117 SER SER C . n 
C 1 118 TYR 118 118 118 TYR TYR C . n 
C 1 119 GLN 119 119 119 GLN GLN C . n 
C 1 120 ILE 120 120 120 ILE ILE C . n 
C 1 121 GLY 121 121 121 GLY GLY C . n 
C 1 122 ASP 122 122 122 ASP ASP C . n 
C 1 123 THR 123 123 123 THR THR C . n 
C 1 124 ASN 124 124 124 ASN ASN C . n 
C 1 125 ALA 125 125 125 ALA ALA C . n 
C 1 126 TYR 126 126 126 TYR TYR C . n 
C 1 127 GLY 127 127 127 GLY GLY C . n 
C 1 128 LYS 128 128 128 LYS LYS C . n 
C 1 129 GLY 129 129 129 GLY GLY C . n 
C 1 130 ILE 130 130 130 ILE ILE C . n 
C 1 131 ASN 131 131 131 ASN ASN C . n 
C 1 132 ASP 132 132 132 ASP ASP C . n 
C 1 133 LEU 133 133 133 LEU LEU C . n 
C 1 134 CYS 134 134 134 CYS CYS C . n 
C 1 135 PHE 135 135 135 PHE PHE C . n 
C 1 136 VAL 136 136 136 VAL VAL C . n 
C 1 137 PHE 137 137 137 PHE PHE C . n 
C 1 138 TYR 138 138 138 TYR TYR C . n 
C 1 139 TYR 139 139 139 TYR TYR C . n 
C 1 140 MET 140 140 140 MET MET C . n 
C 1 141 ILE 141 141 141 ILE ILE C . n 
C 1 142 PHE 142 142 142 PHE PHE C . n 
C 1 143 PHE 143 143 143 PHE PHE C . n 
C 1 144 THR 144 144 144 THR THR C . n 
C 1 145 PHE 145 145 145 PHE PHE C . n 
C 1 146 LEU 146 146 146 LEU LEU C . n 
C 1 147 ARG 147 147 147 ARG ARG C . n 
C 1 148 GLU 148 148 148 GLU GLU C . n 
C 1 149 PHE 149 149 149 PHE PHE C . n 
C 1 150 LEU 150 150 150 LEU LEU C . n 
C 1 151 MET 151 151 151 MET MET C . n 
C 1 152 ASP 152 152 152 ASP ASP C . n 
C 1 153 VAL 153 153 153 VAL VAL C . n 
C 1 154 VAL 154 154 154 VAL VAL C . n 
C 1 155 ILE 155 155 155 ILE ILE C . n 
C 1 156 ARG 156 156 156 ARG ARG C . n 
C 1 157 PRO 157 157 157 PRO PRO C . n 
C 1 158 PHE 158 158 158 PHE PHE C . n 
C 1 159 ALA 159 159 159 ALA ALA C . n 
C 1 160 ILE 160 160 160 ILE ILE C . n 
C 1 161 ARG 161 161 161 ARG ARG C . n 
C 1 162 LEU 162 162 162 LEU LEU C . n 
C 1 163 HIS 163 163 163 HIS HIS C . n 
C 1 164 VAL 164 164 164 VAL VAL C . n 
C 1 165 THR 165 165 165 THR THR C . n 
C 1 166 SER 166 166 166 SER SER C . n 
C 1 167 LYS 167 167 167 LYS LYS C . n 
C 1 168 HIS 168 168 168 HIS HIS C . n 
C 1 169 ARG 169 169 169 ARG ARG C . n 
C 1 170 ILE 170 170 170 ILE ILE C . n 
C 1 171 LYS 171 171 171 LYS LYS C . n 
C 1 172 ARG 172 172 172 ARG ARG C . n 
C 1 173 ILE 173 173 173 ILE ILE C . n 
C 1 174 MET 174 174 174 MET MET C . n 
C 1 175 GLU 175 175 175 GLU GLU C . n 
C 1 176 GLN 176 176 176 GLN GLN C . n 
C 1 177 MET 177 177 177 MET MET C . n 
C 1 178 TYR 178 178 178 TYR TYR C . n 
C 1 179 ALA 179 179 179 ALA ALA C . n 
C 1 180 ILE 180 180 180 ILE ILE C . n 
C 1 181 PHE 181 181 181 PHE PHE C . n 
C 1 182 TYR 182 182 182 TYR TYR C . n 
C 1 183 THR 183 183 183 THR THR C . n 
C 1 184 GLY 184 184 184 GLY GLY C . n 
C 1 185 VAL 185 185 185 VAL VAL C . n 
C 1 186 SER 186 186 186 SER SER C . n 
C 1 187 GLY 187 187 187 GLY GLY C . n 
C 1 188 PRO 188 188 188 PRO PRO C . n 
C 1 189 PHE 189 189 189 PHE PHE C . n 
C 1 190 GLY 190 190 190 GLY GLY C . n 
C 1 191 ILE 191 191 191 ILE ILE C . n 
C 1 192 TYR 192 192 192 TYR TYR C . n 
C 1 193 CYS 193 193 193 CYS CYS C . n 
C 1 194 MET 194 194 194 MET MET C . n 
C 1 195 TYR 195 195 195 TYR TYR C . n 
C 1 196 HIS 196 196 196 HIS HIS C . n 
C 1 197 SER 197 197 197 SER SER C . n 
C 1 198 ASP 198 198 198 ASP ASP C . n 
C 1 199 LEU 199 199 199 LEU LEU C . n 
C 1 200 TRP 200 200 200 TRP TRP C . n 
C 1 201 PHE 201 201 201 PHE PHE C . n 
C 1 202 PHE 202 202 202 PHE PHE C . n 
C 1 203 ASN 203 203 203 ASN ASN C . n 
C 1 204 THR 204 204 204 THR THR C . n 
C 1 205 LYS 205 205 205 LYS LYS C . n 
C 1 206 ALA 206 206 206 ALA ALA C . n 
C 1 207 MET 207 207 207 MET MET C . n 
C 1 208 TYR 208 208 208 TYR TYR C . n 
C 1 209 ARG 209 209 209 ARG ARG C . n 
C 1 210 THR 210 210 210 THR THR C . n 
C 1 211 TYR 211 211 211 TYR TYR C . n 
C 1 212 PRO 212 212 212 PRO PRO C . n 
C 1 213 ASP 213 213 213 ASP ASP C . n 
C 1 214 PHE 214 214 214 PHE PHE C . n 
C 1 215 THR 215 215 215 THR THR C . n 
C 1 216 ASN 216 216 216 ASN ASN C . n 
C 1 217 PRO 217 217 217 PRO PRO C . n 
C 1 218 PHE 218 218 218 PHE PHE C . n 
C 1 219 LEU 219 219 219 LEU LEU C . n 
C 1 220 PHE 220 220 220 PHE PHE C . n 
C 1 221 LYS 221 221 221 LYS LYS C . n 
C 1 222 VAL 222 222 222 VAL VAL C . n 
C 1 223 PHE 223 223 223 PHE PHE C . n 
C 1 224 TYR 224 224 224 TYR TYR C . n 
C 1 225 LEU 225 225 225 LEU LEU C . n 
C 1 226 GLY 226 226 226 GLY GLY C . n 
C 1 227 GLN 227 227 227 GLN GLN C . n 
C 1 228 ALA 228 228 228 ALA ALA C . n 
C 1 229 ALA 229 229 229 ALA ALA C . n 
C 1 230 PHE 230 230 230 PHE PHE C . n 
C 1 231 TRP 231 231 231 TRP TRP C . n 
C 1 232 ALA 232 232 232 ALA ALA C . n 
C 1 233 GLN 233 233 233 GLN GLN C . n 
C 1 234 GLN 234 234 234 GLN GLN C . n 
C 1 235 ALA 235 235 235 ALA ALA C . n 
C 1 236 CYS 236 236 236 CYS CYS C . n 
C 1 237 ILE 237 237 237 ILE ILE C . n 
C 1 238 LEU 238 238 238 LEU LEU C . n 
C 1 239 VAL 239 239 239 VAL VAL C . n 
C 1 240 LEU 240 240 240 LEU LEU C . n 
C 1 241 GLN 241 241 241 GLN GLN C . n 
C 1 242 LEU 242 242 242 LEU LEU C . n 
C 1 243 GLU 243 243 243 GLU GLU C . n 
C 1 244 LYS 244 244 244 LYS LYS C . n 
C 1 245 PRO 245 245 245 PRO PRO C . n 
C 1 246 ARG 246 246 246 ARG ARG C . n 
C 1 247 LYS 247 247 247 LYS LYS C . n 
C 1 248 ASP 248 248 248 ASP ASP C . n 
C 1 249 HIS 249 249 249 HIS HIS C . n 
C 1 250 ASN 250 250 250 ASN ASN C . n 
C 1 251 GLU 251 251 251 GLU GLU C . n 
C 1 252 LEU 252 252 252 LEU LEU C . n 
C 1 253 THR 253 253 253 THR THR C . n 
C 1 254 PHE 254 254 254 PHE PHE C . n 
C 1 255 HIS 255 255 255 HIS HIS C . n 
C 1 256 HIS 256 256 256 HIS HIS C . n 
C 1 257 ILE 257 257 257 ILE ILE C . n 
C 1 258 VAL 258 258 258 VAL VAL C . n 
C 1 259 THR 259 259 259 THR THR C . n 
C 1 260 LEU 260 260 260 LEU LEU C . n 
C 1 261 LEU 261 261 261 LEU LEU C . n 
C 1 262 LEU 262 262 262 LEU LEU C . n 
C 1 263 ILE 263 263 263 ILE ILE C . n 
C 1 264 TRP 264 264 264 TRP TRP C . n 
C 1 265 SER 265 265 265 SER SER C . n 
C 1 266 SER 266 266 266 SER SER C . n 
C 1 267 TYR 267 267 267 TYR TYR C . n 
C 1 268 VAL 268 268 268 VAL VAL C . n 
C 1 269 PHE 269 269 269 PHE PHE C . n 
C 1 270 HIS 270 270 270 HIS HIS C . n 
C 1 271 PHE 271 271 271 PHE PHE C . n 
C 1 272 THR 272 272 272 THR THR C . n 
C 1 273 LYS 273 273 273 LYS LYS C . n 
C 1 274 MET 274 274 274 MET MET C . n 
C 1 275 GLY 275 275 275 GLY GLY C . n 
C 1 276 LEU 276 276 276 LEU LEU C . n 
C 1 277 PRO 277 277 277 PRO PRO C . n 
C 1 278 ILE 278 278 278 ILE ILE C . n 
C 1 279 TYR 279 279 279 TYR TYR C . n 
C 1 280 ILE 280 280 280 ILE ILE C . n 
C 1 281 THR 281 281 281 THR THR C . n 
C 1 282 MET 282 282 282 MET MET C . n 
C 1 283 ASP 283 283 283 ASP ASP C . n 
C 1 284 VAL 284 284 284 VAL VAL C . n 
C 1 285 SER 285 285 285 SER SER C . n 
C 1 286 ASP 286 286 286 ASP ASP C . n 
C 1 287 PHE 287 287 287 PHE PHE C . n 
C 1 288 LEU 288 288 288 LEU LEU C . n 
C 1 289 LEU 289 289 289 LEU LEU C . n 
C 1 290 SER 290 290 290 SER SER C . n 
C 1 291 PHE 291 291 291 PHE PHE C . n 
C 1 292 SER 292 292 292 SER SER C . n 
C 1 293 LYS 293 293 293 LYS LYS C . n 
C 1 294 THR 294 294 294 THR THR C . n 
C 1 295 LEU 295 295 295 LEU LEU C . n 
C 1 296 ASN 296 296 296 ASN ASN C . n 
C 1 297 TYR 297 297 297 TYR TYR C . n 
C 1 298 LEU 298 298 298 LEU LEU C . n 
C 1 299 ASP 299 299 299 ASP ASP C . n 
C 1 300 SER 300 300 300 SER SER C . n 
C 1 301 GLY 301 301 301 GLY GLY C . n 
C 1 302 LEU 302 302 302 LEU LEU C . n 
C 1 303 ALA 303 303 303 ALA ALA C . n 
C 1 304 PHE 304 304 304 PHE PHE C . n 
C 1 305 PHE 305 305 305 PHE PHE C . n 
C 1 306 SER 306 306 306 SER SER C . n 
C 1 307 PHE 307 307 307 PHE PHE C . n 
C 1 308 ALA 308 308 308 ALA ALA C . n 
C 1 309 ILE 309 309 309 ILE ILE C . n 
C 1 310 PHE 310 310 310 PHE PHE C . n 
C 1 311 VAL 311 311 311 VAL VAL C . n 
C 1 312 VAL 312 312 312 VAL VAL C . n 
C 1 313 ALA 313 313 313 ALA ALA C . n 
C 1 314 TRP 314 314 314 TRP TRP C . n 
C 1 315 ILE 315 315 315 ILE ILE C . n 
C 1 316 TYR 316 316 316 TYR TYR C . n 
C 1 317 LEU 317 317 317 LEU LEU C . n 
C 1 318 ARG 318 318 318 ARG ARG C . n 
C 1 319 HIS 319 319 319 HIS HIS C . n 
C 1 320 TYR 320 320 320 TYR TYR C . n 
C 1 321 ILE 321 321 321 ILE ILE C . n 
C 1 322 ASN 322 322 322 ASN ASN C . n 
C 1 323 LEU 323 323 323 LEU LEU C . n 
C 1 324 LYS 324 324 324 LYS LYS C . n 
C 1 325 ILE 325 325 325 ILE ILE C . n 
C 1 326 LEU 326 326 326 LEU LEU C . n 
C 1 327 TRP 327 327 327 TRP TRP C . n 
C 1 328 SER 328 328 328 SER SER C . n 
C 1 329 VAL 329 329 329 VAL VAL C . n 
C 1 330 LEU 330 330 330 LEU LEU C . n 
C 1 331 THR 331 331 331 THR THR C . n 
C 1 332 GLN 332 332 332 GLN GLN C . n 
C 1 333 PHE 333 333 333 PHE PHE C . n 
C 1 334 ARG 334 334 334 ARG ARG C . n 
C 1 335 THR 335 335 335 THR THR C . n 
C 1 336 GLU 336 336 336 GLU GLU C . n 
C 1 337 GLY 337 337 337 GLY GLY C . n 
C 1 338 ASN 338 338 338 ASN ASN C . n 
C 1 339 TYR 339 339 339 TYR TYR C . n 
C 1 340 VAL 340 340 340 VAL VAL C . n 
C 1 341 LEU 341 341 341 LEU LEU C . n 
C 1 342 ASN 342 342 342 ASN ASN C . n 
C 1 343 PHE 343 343 343 PHE PHE C . n 
C 1 344 ALA 344 344 344 ALA ALA C . n 
C 1 345 THR 345 345 345 THR THR C . n 
C 1 346 GLN 346 346 346 GLN GLN C . n 
C 1 347 GLN 347 347 347 GLN GLN C . n 
C 1 348 TYR 348 348 348 TYR TYR C . n 
C 1 349 LYS 349 349 349 LYS LYS C . n 
C 1 350 CYS 350 350 350 CYS CYS C . n 
C 1 351 TRP 351 351 351 TRP TRP C . n 
C 1 352 ILE 352 352 352 ILE ILE C . n 
C 1 353 SER 353 353 353 SER SER C . n 
C 1 354 LEU 354 354 354 LEU LEU C . n 
C 1 355 PRO 355 355 355 PRO PRO C . n 
C 1 356 ILE 356 356 356 ILE ILE C . n 
C 1 357 VAL 357 357 357 VAL VAL C . n 
C 1 358 PHE 358 358 358 PHE PHE C . n 
C 1 359 VAL 359 359 359 VAL VAL C . n 
C 1 360 LEU 360 360 360 LEU LEU C . n 
C 1 361 ILE 361 361 361 ILE ILE C . n 
C 1 362 GLY 362 362 362 GLY GLY C . n 
C 1 363 ALA 363 363 363 ALA ALA C . n 
C 1 364 LEU 364 364 364 LEU LEU C . n 
C 1 365 GLN 365 365 365 GLN GLN C . n 
C 1 366 LEU 366 366 366 LEU LEU C . n 
C 1 367 VAL 367 367 367 VAL VAL C . n 
C 1 368 ASN 368 368 368 ASN ASN C . n 
C 1 369 LEU 369 369 369 LEU LEU C . n 
C 1 370 TYR 370 370 370 TYR TYR C . n 
C 1 371 TRP 371 371 371 TRP TRP C . n 
C 1 372 LEU 372 372 372 LEU LEU C . n 
C 1 373 PHE 373 373 373 PHE PHE C . n 
C 1 374 LEU 374 374 374 LEU LEU C . n 
C 1 375 ILE 375 375 375 ILE ILE C . n 
C 1 376 PHE 376 376 376 PHE PHE C . n 
C 1 377 ARG 377 377 377 ARG ARG C . n 
C 1 378 VAL 378 378 378 VAL VAL C . n 
C 1 379 LEU 379 379 379 LEU LEU C . n 
C 1 380 TYR 380 380 380 TYR TYR C . n 
C 1 381 ARG 381 381 381 ARG ARG C . n 
C 1 382 ILE 382 382 382 ILE ILE C . n 
C 1 383 LEU 383 383 383 LEU LEU C . n 
C 1 384 TRP 384 384 384 TRP TRP C . n 
C 1 385 ARG 385 385 385 ARG ARG C . n 
C 1 386 GLY 386 386 ?   ?   ?   C . n 
C 1 387 ILE 387 387 ?   ?   ?   C . n 
C 1 388 LEU 388 388 ?   ?   ?   C . n 
C 1 389 LYS 389 389 ?   ?   ?   C . n 
C 1 390 ASP 390 390 ?   ?   ?   C . n 
C 1 391 ASP 391 391 ?   ?   ?   C . n 
C 1 392 ARG 392 392 ?   ?   ?   C . n 
C 1 393 SER 393 393 ?   ?   ?   C . n 
C 1 394 ASP 394 394 ?   ?   ?   C . n 
C 1 395 SER 395 395 ?   ?   ?   C . n 
C 1 396 GLU 396 396 ?   ?   ?   C . n 
C 1 397 SER 397 397 ?   ?   ?   C . n 
C 1 398 ASP 398 398 ?   ?   ?   C . n 
C 1 399 GLU 399 399 ?   ?   ?   C . n 
C 1 400 GLU 400 400 ?   ?   ?   C . n 
C 1 401 SER 401 401 ?   ?   ?   C . n 
C 1 402 ASP 402 402 ?   ?   ?   C . n 
C 1 403 GLU 403 403 ?   ?   ?   C . n 
C 1 404 SER 404 404 ?   ?   ?   C . n 
C 1 405 SER 405 405 ?   ?   ?   C . n 
C 1 406 THR 406 406 ?   ?   ?   C . n 
C 1 407 THR 407 407 ?   ?   ?   C . n 
C 1 408 PRO 408 408 ?   ?   ?   C . n 
C 1 409 THR 409 409 ?   ?   ?   C . n 
C 1 410 ASP 410 410 ?   ?   ?   C . n 
C 1 411 SER 411 411 ?   ?   ?   C . n 
C 1 412 THR 412 412 ?   ?   ?   C . n 
C 1 413 PRO 413 413 ?   ?   ?   C . n 
C 1 414 THR 414 414 ?   ?   ?   C . n 
C 1 415 LYS 415 415 ?   ?   ?   C . n 
C 1 416 LYS 416 416 ?   ?   ?   C . n 
C 1 417 ASP 417 417 ?   ?   ?   C . n 
C 1 418 ILE 418 418 ?   ?   ?   C . n 
C 1 419 LEU 419 419 ?   ?   ?   C . n 
C 1 420 GLU 420 420 ?   ?   ?   C . n 
C 1 421 ASP 421 421 ?   ?   ?   C . n 
C 1 422 TYR 422 422 ?   ?   ?   C . n 
C 1 423 LYS 423 423 ?   ?   ?   C . n 
C 1 424 ASP 424 424 ?   ?   ?   C . n 
C 1 425 ASP 425 425 ?   ?   ?   C . n 
C 1 426 ASP 426 426 ?   ?   ?   C . n 
C 1 427 ASP 427 427 ?   ?   ?   C . n 
C 1 428 LYS 428 428 ?   ?   ?   C . n 
D 2 1   MET 1   1   ?   ?   ?   D . n 
D 2 2   SER 2   2   ?   ?   ?   D . n 
D 2 3   GLN 3   3   ?   ?   ?   D . n 
D 2 4   PRO 4   4   ?   ?   ?   D . n 
D 2 5   THR 5   5   ?   ?   ?   D . n 
D 2 6   PRO 6   6   ?   ?   ?   D . n 
D 2 7   ILE 7   7   ?   ?   ?   D . n 
D 2 8   ILE 8   8   ?   ?   ?   D . n 
D 2 9   THR 9   9   ?   ?   ?   D . n 
D 2 10  THR 10  10  ?   ?   ?   D . n 
D 2 11  LYS 11  11  ?   ?   ?   D . n 
D 2 12  SER 12  12  ?   ?   ?   D . n 
D 2 13  ALA 13  13  ?   ?   ?   D . n 
D 2 14  ALA 14  14  ?   ?   ?   D . n 
D 2 15  LYS 15  15  ?   ?   ?   D . n 
D 2 16  PRO 16  16  ?   ?   ?   D . n 
D 2 17  LYS 17  17  ?   ?   ?   D . n 
D 2 18  PRO 18  18  18  PRO PRO D . n 
D 2 19  LYS 19  19  19  LYS LYS D . n 
D 2 20  ILE 20  20  20  ILE ILE D . n 
D 2 21  PHE 21  21  21  PHE PHE D . n 
D 2 22  ASN 22  22  22  ASN ASN D . n 
D 2 23  LEU 23  23  23  LEU LEU D . n 
D 2 24  PHE 24  24  24  PHE PHE D . n 
D 2 25  ARG 25  25  25  ARG ARG D . n 
D 2 26  VAL 26  26  26  VAL VAL D . n 
D 2 27  CYS 27  27  27  CYS CYS D . n 
D 2 28  PHE 28  28  28  PHE PHE D . n 
D 2 29  ILE 29  29  29  ILE ILE D . n 
D 2 30  SER 30  30  30  SER SER D . n 
D 2 31  LEU 31  31  31  LEU LEU D . n 
D 2 32  LEU 32  32  32  LEU LEU D . n 
D 2 33  LEU 33  33  33  LEU LEU D . n 
D 2 34  ILE 34  34  34  ILE ILE D . n 
D 2 35  ALA 35  35  35  ALA ALA D . n 
D 2 36  ALA 36  36  36  ALA ALA D . n 
D 2 37  VAL 37  37  37  VAL VAL D . n 
D 2 38  GLU 38  38  38  GLU GLU D . n 
D 2 39  TYR 39  39  39  TYR TYR D . n 
D 2 40  PHE 40  40  40  PHE PHE D . n 
D 2 41  LYS 41  41  41  LYS LYS D . n 
D 2 42  TYR 42  42  42  TYR TYR D . n 
D 2 43  GLY 43  43  43  GLY GLY D . n 
D 2 44  THR 44  44  44  THR THR D . n 
D 2 45  ARG 45  45  45  ARG ARG D . n 
D 2 46  ILE 46  46  46  ILE ILE D . n 
D 2 47  ASN 47  47  47  ASN ASN D . n 
D 2 48  TYR 48  48  48  TYR TYR D . n 
D 2 49  GLU 49  49  49  GLU GLU D . n 
D 2 50  TRP 50  50  50  TRP TRP D . n 
D 2 51  PHE 51  51  51  PHE PHE D . n 
D 2 52  HIS 52  52  52  HIS HIS D . n 
D 2 53  CYS 53  53  53  CYS CYS D . n 
D 2 54  THR 54  54  54  THR THR D . n 
D 2 55  PRO 55  55  55  PRO PRO D . n 
D 2 56  ILE 56  56  56  ILE ILE D . n 
D 2 57  LYS 57  57  57  LYS LYS D . n 
D 2 58  GLU 58  58  58  GLU GLU D . n 
D 2 59  PRO 59  59  59  PRO PRO D . n 
D 2 60  GLN 60  60  60  GLN GLN D . n 
D 2 61  SER 61  61  61  SER SER D . n 
D 2 62  GLY 62  62  62  GLY GLY D . n 
D 2 63  SER 63  63  63  SER SER D . n 
D 2 64  VAL 64  64  64  VAL VAL D . n 
D 2 65  ILE 65  65  65  ILE ILE D . n 
D 2 66  LYS 66  66  66  LYS LYS D . n 
D 2 67  LEU 67  67  67  LEU LEU D . n 
D 2 68  TRP 68  68  68  TRP TRP D . n 
D 2 69  ALA 69  69  69  ALA ALA D . n 
D 2 70  ARG 70  70  70  ARG ARG D . n 
D 2 71  GLY 71  71  71  GLY GLY D . n 
D 2 72  GLY 72  72  72  GLY GLY D . n 
D 2 73  PRO 73  73  73  PRO PRO D . n 
D 2 74  SER 74  74  74  SER SER D . n 
D 2 75  CYS 75  75  75  CYS CYS D . n 
D 2 76  ASP 76  76  76  ASP ASP D . n 
D 2 77  LYS 77  77  77  LYS LYS D . n 
D 2 78  ARG 78  78  78  ARG ARG D . n 
D 2 79  GLY 79  79  79  GLY GLY D . n 
D 2 80  GLU 80  80  80  GLU GLU D . n 
D 2 81  TYR 81  81  81  TYR TYR D . n 
D 2 82  LYS 82  82  82  LYS LYS D . n 
D 2 83  THR 83  83  83  THR THR D . n 
D 2 84  ILE 84  84  84  ILE ILE D . n 
D 2 85  VAL 85  85  85  VAL VAL D . n 
D 2 86  LYS 86  86  86  LYS LYS D . n 
D 2 87  ARG 87  87  87  ARG ARG D . n 
D 2 88  ILE 88  88  88  ILE ILE D . n 
D 2 89  THR 89  89  89  THR THR D . n 
D 2 90  ARG 90  90  90  ARG ARG D . n 
D 2 91  ASP 91  91  91  ASP ASP D . n 
D 2 92  TYR 92  92  92  TYR TYR D . n 
D 2 93  GLU 93  93  93  GLU GLU D . n 
D 2 94  PRO 94  94  94  PRO PRO D . n 
D 2 95  ASN 95  95  95  ASN ASN D . n 
D 2 96  ASP 96  96  96  ASP ASP D . n 
D 2 97  GLU 97  97  97  GLU GLU D . n 
D 2 98  HIS 98  98  98  HIS HIS D . n 
D 2 99  LEU 99  99  99  LEU LEU D . n 
D 2 100 SER 100 100 100 SER SER D . n 
D 2 101 PHE 101 101 101 PHE PHE D . n 
D 2 102 CYS 102 102 102 CYS CYS D . n 
D 2 103 ILE 103 103 103 ILE ILE D . n 
D 2 104 ILE 104 104 104 ILE ILE D . n 
D 2 105 GLU 105 105 105 GLU GLU D . n 
D 2 106 ASN 106 106 106 ASN ASN D . n 
D 2 107 ASP 107 107 107 ASP ASP D . n 
D 2 108 ASN 108 108 108 ASN ASN D . n 
D 2 109 VAL 109 109 109 VAL VAL D . n 
D 2 110 PRO 110 110 110 PRO PRO D . n 
D 2 111 PRO 111 111 111 PRO PRO D . n 
D 2 112 VAL 112 112 112 VAL VAL D . n 
D 2 113 HIS 113 113 113 HIS HIS D . n 
D 2 114 TYR 114 114 114 TYR TYR D . n 
D 2 115 PRO 115 115 115 PRO PRO D . n 
D 2 116 ILE 116 116 116 ILE ILE D . n 
D 2 117 HIS 117 117 117 HIS HIS D . n 
D 2 118 GLU 118 118 118 GLU GLU D . n 
D 2 119 ASP 119 119 119 ASP ASP D . n 
D 2 120 LYS 120 120 120 LYS LYS D . n 
D 2 121 GLY 121 121 121 GLY GLY D . n 
D 2 122 GLU 122 122 122 GLU GLU D . n 
D 2 123 PRO 123 123 123 PRO PRO D . n 
D 2 124 GLY 124 124 124 GLY GLY D . n 
D 2 125 TYR 125 125 125 TYR TYR D . n 
D 2 126 VAL 126 126 126 VAL VAL D . n 
D 2 127 ALA 127 127 127 ALA ALA D . n 
D 2 128 TYR 128 128 128 TYR TYR D . n 
D 2 129 VAL 129 129 129 VAL VAL D . n 
D 2 130 GLY 130 130 130 GLY GLY D . n 
D 2 131 TYR 131 131 131 TYR TYR D . n 
D 2 132 ASP 132 132 132 ASP ASP D . n 
D 2 133 THR 133 133 133 THR THR D . n 
D 2 134 ASP 134 134 134 ASP ASP D . n 
D 2 135 SER 135 135 135 SER SER D . n 
D 2 136 GLU 136 136 136 GLU GLU D . n 
D 2 137 LEU 137 137 137 LEU LEU D . n 
D 2 138 VAL 138 138 138 VAL VAL D . n 
D 2 139 GLN 139 139 139 GLN GLN D . n 
D 2 140 GLU 140 140 140 GLU GLU D . n 
D 2 141 LEU 141 141 141 LEU LEU D . n 
D 2 142 CYS 142 142 142 CYS CYS D . n 
D 2 143 ALA 143 143 143 ALA ALA D . n 
D 2 144 ASP 144 144 144 ASP ASP D . n 
D 2 145 SER 145 145 145 SER SER D . n 
D 2 146 THR 146 146 146 THR THR D . n 
D 2 147 ILE 147 147 147 ILE ILE D . n 
D 2 148 TYR 148 148 148 TYR TYR D . n 
D 2 149 HIS 149 149 149 HIS HIS D . n 
D 2 150 MET 150 150 150 MET MET D . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 6PL 1 501 3 6PL 6PL A . 
F 3 6PL 1 502 4 6PL 6PL A . 
G 3 6PL 1 201 1 6PL 6PL B . 
H 3 6PL 1 202 2 6PL 6PL B . 
I 3 6PL 1 501 7 6PL 6PL C . 
J 3 6PL 1 502 8 6PL 6PL C . 
K 3 6PL 1 201 5 6PL 6PL D . 
L 3 6PL 1 202 6 6PL 6PL D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 N 1 A 6PL 501 ? C26 ? E 6PL 1 C26 
2   1 N 1 A 6PL 501 ? C25 ? E 6PL 1 C25 
3   1 N 1 A 6PL 501 ? C24 ? E 6PL 1 C24 
4   1 N 1 A 6PL 501 ? C23 ? E 6PL 1 C23 
5   1 N 1 A 6PL 501 ? C22 ? E 6PL 1 C22 
6   1 N 1 A 6PL 501 ? C21 ? E 6PL 1 C21 
7   1 N 1 A 6PL 501 ? C20 ? E 6PL 1 C20 
8   1 N 1 A 6PL 501 ? C19 ? E 6PL 1 C19 
9   1 N 1 A 6PL 501 ? C18 ? E 6PL 1 C18 
10  1 N 1 A 6PL 501 ? C17 ? E 6PL 1 C17 
11  1 N 1 A 6PL 501 ? C16 ? E 6PL 1 C16 
12  1 N 1 A 6PL 501 ? C15 ? E 6PL 1 C15 
13  1 N 1 A 6PL 501 ? C14 ? E 6PL 1 C14 
14  1 N 1 A 6PL 501 ? C13 ? E 6PL 1 C13 
15  1 N 1 A 6PL 501 ? C12 ? E 6PL 1 C12 
16  1 N 1 A 6PL 501 ? C11 ? E 6PL 1 C11 
17  1 N 1 A 6PL 501 ? O11 ? E 6PL 1 O11 
18  1 N 1 A 6PL 501 ? O3  ? E 6PL 1 O3  
19  1 N 1 A 6PL 501 ? C3  ? E 6PL 1 C3  
20  1 N 1 A 6PL 501 ? C2  ? E 6PL 1 C2  
21  1 N 1 A 6PL 501 ? C1  ? E 6PL 1 C1  
22  1 N 1 A 6PL 501 ? O3P ? E 6PL 1 O3P 
23  1 N 1 A 6PL 501 ? P   ? E 6PL 1 P   
24  1 N 1 A 6PL 501 ? O1P ? E 6PL 1 O1P 
25  1 N 1 A 6PL 501 ? O2P ? E 6PL 1 O2P 
26  1 N 1 A 6PL 501 ? O4P ? E 6PL 1 O4P 
27  1 N 1 A 6PL 501 ? C4  ? E 6PL 1 C4  
28  1 N 1 A 6PL 501 ? C5  ? E 6PL 1 C5  
29  1 N 1 A 6PL 501 ? N   ? E 6PL 1 N   
30  1 N 1 A 6PL 501 ? C7  ? E 6PL 1 C7  
31  1 N 1 A 6PL 501 ? C8  ? E 6PL 1 C8  
32  1 N 1 A 6PL 501 ? C6  ? E 6PL 1 C6  
33  1 N 1 A 6PL 501 ? O2  ? E 6PL 1 O2  
34  1 N 1 A 6PL 501 ? O31 ? E 6PL 1 O31 
35  1 N 1 A 6PL 502 ? C26 ? F 6PL 1 C26 
36  1 N 1 A 6PL 502 ? C25 ? F 6PL 1 C25 
37  1 N 1 A 6PL 502 ? C24 ? F 6PL 1 C24 
38  1 N 1 A 6PL 502 ? C23 ? F 6PL 1 C23 
39  1 N 1 A 6PL 502 ? C22 ? F 6PL 1 C22 
40  1 N 1 A 6PL 502 ? C21 ? F 6PL 1 C21 
41  1 N 1 A 6PL 502 ? C20 ? F 6PL 1 C20 
42  1 N 1 A 6PL 502 ? C19 ? F 6PL 1 C19 
43  1 N 1 A 6PL 502 ? C18 ? F 6PL 1 C18 
44  1 N 1 A 6PL 502 ? C17 ? F 6PL 1 C17 
45  1 N 1 A 6PL 502 ? C16 ? F 6PL 1 C16 
46  1 N 1 A 6PL 502 ? C15 ? F 6PL 1 C15 
47  1 N 1 A 6PL 502 ? C14 ? F 6PL 1 C14 
48  1 N 1 A 6PL 502 ? C13 ? F 6PL 1 C13 
49  1 N 1 A 6PL 502 ? C12 ? F 6PL 1 C12 
50  1 N 1 A 6PL 502 ? C11 ? F 6PL 1 C11 
51  1 N 1 A 6PL 502 ? O11 ? F 6PL 1 O11 
52  1 N 1 A 6PL 502 ? O3  ? F 6PL 1 O3  
53  1 N 1 A 6PL 502 ? C3  ? F 6PL 1 C3  
54  1 N 1 A 6PL 502 ? C2  ? F 6PL 1 C2  
55  1 N 1 A 6PL 502 ? C1  ? F 6PL 1 C1  
56  1 N 1 A 6PL 502 ? O3P ? F 6PL 1 O3P 
57  1 N 1 A 6PL 502 ? P   ? F 6PL 1 P   
58  1 N 1 A 6PL 502 ? O1P ? F 6PL 1 O1P 
59  1 N 1 A 6PL 502 ? O2P ? F 6PL 1 O2P 
60  1 N 1 A 6PL 502 ? O4P ? F 6PL 1 O4P 
61  1 N 1 A 6PL 502 ? C4  ? F 6PL 1 C4  
62  1 N 1 A 6PL 502 ? C5  ? F 6PL 1 C5  
63  1 N 1 A 6PL 502 ? N   ? F 6PL 1 N   
64  1 N 1 A 6PL 502 ? C7  ? F 6PL 1 C7  
65  1 N 1 A 6PL 502 ? C8  ? F 6PL 1 C8  
66  1 N 1 A 6PL 502 ? C6  ? F 6PL 1 C6  
67  1 N 1 A 6PL 502 ? O2  ? F 6PL 1 O2  
68  1 N 1 A 6PL 502 ? O31 ? F 6PL 1 O31 
69  1 N 1 B 6PL 201 ? C4  ? G 6PL 1 C4  
70  1 N 1 B 6PL 201 ? C5  ? G 6PL 1 C5  
71  1 N 1 B 6PL 201 ? N   ? G 6PL 1 N   
72  1 N 1 B 6PL 201 ? C7  ? G 6PL 1 C7  
73  1 N 1 B 6PL 201 ? C8  ? G 6PL 1 C8  
74  1 N 1 B 6PL 201 ? C6  ? G 6PL 1 C6  
75  1 N 1 B 6PL 201 ? C43 ? G 6PL 1 C43 
76  1 N 1 B 6PL 201 ? C44 ? G 6PL 1 C44 
77  1 N 1 B 6PL 201 ? C45 ? G 6PL 1 C45 
78  1 N 1 B 6PL 201 ? C46 ? G 6PL 1 C46 
79  1 N 1 B 6PL 201 ? C47 ? G 6PL 1 C47 
80  1 N 1 B 6PL 201 ? C48 ? G 6PL 1 C48 
81  1 N 1 B 6PL 202 ? C26 ? H 6PL 1 C26 
82  1 N 1 B 6PL 202 ? C25 ? H 6PL 1 C25 
83  1 N 1 B 6PL 202 ? C24 ? H 6PL 1 C24 
84  1 N 1 B 6PL 202 ? C23 ? H 6PL 1 C23 
85  1 N 1 B 6PL 202 ? C22 ? H 6PL 1 C22 
86  1 N 1 B 6PL 202 ? C21 ? H 6PL 1 C21 
87  1 N 1 B 6PL 202 ? C20 ? H 6PL 1 C20 
88  1 N 1 B 6PL 202 ? C19 ? H 6PL 1 C19 
89  1 N 1 B 6PL 202 ? C18 ? H 6PL 1 C18 
90  1 N 1 B 6PL 202 ? C17 ? H 6PL 1 C17 
91  1 N 1 B 6PL 202 ? C16 ? H 6PL 1 C16 
92  1 N 1 B 6PL 202 ? C15 ? H 6PL 1 C15 
93  1 N 1 B 6PL 202 ? C14 ? H 6PL 1 C14 
94  1 N 1 B 6PL 202 ? C13 ? H 6PL 1 C13 
95  1 N 1 B 6PL 202 ? C12 ? H 6PL 1 C12 
96  1 N 1 B 6PL 202 ? C11 ? H 6PL 1 C11 
97  1 N 1 B 6PL 202 ? O11 ? H 6PL 1 O11 
98  1 N 1 B 6PL 202 ? O3  ? H 6PL 1 O3  
99  1 N 1 B 6PL 202 ? C3  ? H 6PL 1 C3  
100 1 N 1 B 6PL 202 ? C2  ? H 6PL 1 C2  
101 1 N 1 B 6PL 202 ? C1  ? H 6PL 1 C1  
102 1 N 1 B 6PL 202 ? O3P ? H 6PL 1 O3P 
103 1 N 1 B 6PL 202 ? P   ? H 6PL 1 P   
104 1 N 1 B 6PL 202 ? O1P ? H 6PL 1 O1P 
105 1 N 1 B 6PL 202 ? O2P ? H 6PL 1 O2P 
106 1 N 1 B 6PL 202 ? O4P ? H 6PL 1 O4P 
107 1 N 1 B 6PL 202 ? C4  ? H 6PL 1 C4  
108 1 N 1 B 6PL 202 ? C5  ? H 6PL 1 C5  
109 1 N 1 B 6PL 202 ? N   ? H 6PL 1 N   
110 1 N 1 B 6PL 202 ? C7  ? H 6PL 1 C7  
111 1 N 1 B 6PL 202 ? C8  ? H 6PL 1 C8  
112 1 N 1 B 6PL 202 ? C6  ? H 6PL 1 C6  
113 1 N 1 B 6PL 202 ? O2  ? H 6PL 1 O2  
114 1 N 1 B 6PL 202 ? O31 ? H 6PL 1 O31 
115 1 N 1 C 6PL 501 ? C26 ? I 6PL 1 C26 
116 1 N 1 C 6PL 501 ? C25 ? I 6PL 1 C25 
117 1 N 1 C 6PL 501 ? C24 ? I 6PL 1 C24 
118 1 N 1 C 6PL 501 ? C23 ? I 6PL 1 C23 
119 1 N 1 C 6PL 501 ? C22 ? I 6PL 1 C22 
120 1 N 1 C 6PL 501 ? C21 ? I 6PL 1 C21 
121 1 N 1 C 6PL 501 ? C20 ? I 6PL 1 C20 
122 1 N 1 C 6PL 501 ? C19 ? I 6PL 1 C19 
123 1 N 1 C 6PL 501 ? C18 ? I 6PL 1 C18 
124 1 N 1 C 6PL 501 ? C17 ? I 6PL 1 C17 
125 1 N 1 C 6PL 501 ? C16 ? I 6PL 1 C16 
126 1 N 1 C 6PL 501 ? C15 ? I 6PL 1 C15 
127 1 N 1 C 6PL 501 ? C14 ? I 6PL 1 C14 
128 1 N 1 C 6PL 501 ? C13 ? I 6PL 1 C13 
129 1 N 1 C 6PL 501 ? C12 ? I 6PL 1 C12 
130 1 N 1 C 6PL 501 ? C11 ? I 6PL 1 C11 
131 1 N 1 C 6PL 501 ? O11 ? I 6PL 1 O11 
132 1 N 1 C 6PL 501 ? O3  ? I 6PL 1 O3  
133 1 N 1 C 6PL 501 ? C3  ? I 6PL 1 C3  
134 1 N 1 C 6PL 501 ? C2  ? I 6PL 1 C2  
135 1 N 1 C 6PL 501 ? C1  ? I 6PL 1 C1  
136 1 N 1 C 6PL 501 ? O3P ? I 6PL 1 O3P 
137 1 N 1 C 6PL 501 ? P   ? I 6PL 1 P   
138 1 N 1 C 6PL 501 ? O1P ? I 6PL 1 O1P 
139 1 N 1 C 6PL 501 ? O2P ? I 6PL 1 O2P 
140 1 N 1 C 6PL 501 ? O4P ? I 6PL 1 O4P 
141 1 N 1 C 6PL 501 ? C4  ? I 6PL 1 C4  
142 1 N 1 C 6PL 501 ? C5  ? I 6PL 1 C5  
143 1 N 1 C 6PL 501 ? N   ? I 6PL 1 N   
144 1 N 1 C 6PL 501 ? C7  ? I 6PL 1 C7  
145 1 N 1 C 6PL 501 ? C8  ? I 6PL 1 C8  
146 1 N 1 C 6PL 501 ? C6  ? I 6PL 1 C6  
147 1 N 1 C 6PL 501 ? O2  ? I 6PL 1 O2  
148 1 N 1 C 6PL 501 ? O31 ? I 6PL 1 O31 
149 1 N 1 C 6PL 502 ? C26 ? J 6PL 1 C26 
150 1 N 1 C 6PL 502 ? C25 ? J 6PL 1 C25 
151 1 N 1 C 6PL 502 ? C24 ? J 6PL 1 C24 
152 1 N 1 C 6PL 502 ? C23 ? J 6PL 1 C23 
153 1 N 1 C 6PL 502 ? C22 ? J 6PL 1 C22 
154 1 N 1 C 6PL 502 ? C21 ? J 6PL 1 C21 
155 1 N 1 C 6PL 502 ? C20 ? J 6PL 1 C20 
156 1 N 1 C 6PL 502 ? C19 ? J 6PL 1 C19 
157 1 N 1 C 6PL 502 ? C18 ? J 6PL 1 C18 
158 1 N 1 C 6PL 502 ? C17 ? J 6PL 1 C17 
159 1 N 1 C 6PL 502 ? C16 ? J 6PL 1 C16 
160 1 N 1 C 6PL 502 ? C15 ? J 6PL 1 C15 
161 1 N 1 C 6PL 502 ? C14 ? J 6PL 1 C14 
162 1 N 1 C 6PL 502 ? C13 ? J 6PL 1 C13 
163 1 N 1 C 6PL 502 ? C12 ? J 6PL 1 C12 
164 1 N 1 C 6PL 502 ? C11 ? J 6PL 1 C11 
165 1 N 1 C 6PL 502 ? O11 ? J 6PL 1 O11 
166 1 N 1 C 6PL 502 ? O3  ? J 6PL 1 O3  
167 1 N 1 C 6PL 502 ? C3  ? J 6PL 1 C3  
168 1 N 1 C 6PL 502 ? C2  ? J 6PL 1 C2  
169 1 N 1 C 6PL 502 ? C1  ? J 6PL 1 C1  
170 1 N 1 C 6PL 502 ? O3P ? J 6PL 1 O3P 
171 1 N 1 C 6PL 502 ? P   ? J 6PL 1 P   
172 1 N 1 C 6PL 502 ? O1P ? J 6PL 1 O1P 
173 1 N 1 C 6PL 502 ? O2P ? J 6PL 1 O2P 
174 1 N 1 C 6PL 502 ? O4P ? J 6PL 1 O4P 
175 1 N 1 C 6PL 502 ? C4  ? J 6PL 1 C4  
176 1 N 1 C 6PL 502 ? C5  ? J 6PL 1 C5  
177 1 N 1 C 6PL 502 ? N   ? J 6PL 1 N   
178 1 N 1 C 6PL 502 ? C7  ? J 6PL 1 C7  
179 1 N 1 C 6PL 502 ? C8  ? J 6PL 1 C8  
180 1 N 1 C 6PL 502 ? C6  ? J 6PL 1 C6  
181 1 N 1 C 6PL 502 ? O2  ? J 6PL 1 O2  
182 1 N 1 C 6PL 502 ? O31 ? J 6PL 1 O31 
183 1 N 1 D 6PL 201 ? C4  ? K 6PL 1 C4  
184 1 N 1 D 6PL 201 ? C5  ? K 6PL 1 C5  
185 1 N 1 D 6PL 201 ? N   ? K 6PL 1 N   
186 1 N 1 D 6PL 201 ? C7  ? K 6PL 1 C7  
187 1 N 1 D 6PL 201 ? C8  ? K 6PL 1 C8  
188 1 N 1 D 6PL 201 ? C6  ? K 6PL 1 C6  
189 1 N 1 D 6PL 201 ? C43 ? K 6PL 1 C43 
190 1 N 1 D 6PL 201 ? C44 ? K 6PL 1 C44 
191 1 N 1 D 6PL 201 ? C45 ? K 6PL 1 C45 
192 1 N 1 D 6PL 201 ? C46 ? K 6PL 1 C46 
193 1 N 1 D 6PL 201 ? C47 ? K 6PL 1 C47 
194 1 N 1 D 6PL 201 ? C48 ? K 6PL 1 C48 
195 1 N 1 D 6PL 202 ? C26 ? L 6PL 1 C26 
196 1 N 1 D 6PL 202 ? C25 ? L 6PL 1 C25 
197 1 N 1 D 6PL 202 ? C24 ? L 6PL 1 C24 
198 1 N 1 D 6PL 202 ? C23 ? L 6PL 1 C23 
199 1 N 1 D 6PL 202 ? C22 ? L 6PL 1 C22 
200 1 N 1 D 6PL 202 ? C21 ? L 6PL 1 C21 
201 1 N 1 D 6PL 202 ? C20 ? L 6PL 1 C20 
202 1 N 1 D 6PL 202 ? C19 ? L 6PL 1 C19 
203 1 N 1 D 6PL 202 ? C18 ? L 6PL 1 C18 
204 1 N 1 D 6PL 202 ? C17 ? L 6PL 1 C17 
205 1 N 1 D 6PL 202 ? C16 ? L 6PL 1 C16 
206 1 N 1 D 6PL 202 ? C15 ? L 6PL 1 C15 
207 1 N 1 D 6PL 202 ? C14 ? L 6PL 1 C14 
208 1 N 1 D 6PL 202 ? C13 ? L 6PL 1 C13 
209 1 N 1 D 6PL 202 ? C12 ? L 6PL 1 C12 
210 1 N 1 D 6PL 202 ? C11 ? L 6PL 1 C11 
211 1 N 1 D 6PL 202 ? O11 ? L 6PL 1 O11 
212 1 N 1 D 6PL 202 ? O3  ? L 6PL 1 O3  
213 1 N 1 D 6PL 202 ? C3  ? L 6PL 1 C3  
214 1 N 1 D 6PL 202 ? C2  ? L 6PL 1 C2  
215 1 N 1 D 6PL 202 ? C1  ? L 6PL 1 C1  
216 1 N 1 D 6PL 202 ? O3P ? L 6PL 1 O3P 
217 1 N 1 D 6PL 202 ? P   ? L 6PL 1 P   
218 1 N 1 D 6PL 202 ? O1P ? L 6PL 1 O1P 
219 1 N 1 D 6PL 202 ? O2P ? L 6PL 1 O2P 
220 1 N 1 D 6PL 202 ? O4P ? L 6PL 1 O4P 
221 1 N 1 D 6PL 202 ? C4  ? L 6PL 1 C4  
222 1 N 1 D 6PL 202 ? C5  ? L 6PL 1 C5  
223 1 N 1 D 6PL 202 ? N   ? L 6PL 1 N   
224 1 N 1 D 6PL 202 ? C7  ? L 6PL 1 C7  
225 1 N 1 D 6PL 202 ? C8  ? L 6PL 1 C8  
226 1 N 1 D 6PL 202 ? C6  ? L 6PL 1 C6  
227 1 N 1 D 6PL 202 ? O2  ? L 6PL 1 O2  
228 1 N 1 D 6PL 202 ? O31 ? L 6PL 1 O31 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8Y2N 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8Y2N 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Y2N 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8Y2N 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.008  ? 7960  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.914  ? 10764 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 27.321 ? 1146  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.058  ? 1140  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.006  ? 1298  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8Y2N 
_struct.title                        'Cryo-EM structure of the apo Lac1-Lip1 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Y2N 
_struct_keywords.text            'Inhibitor, Complex, Transferase' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP LAC1_YEAST P28496 ? 1 
;MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISY
RHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAI
RLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVL
QLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDSGLAFFSFAIFVVAWIYLRHY
INLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILKDDRSDSESDEE
SDESSTTPTDSTPTKKDI
;
1 
2 UNP LIP1_YEAST Q03579 ? 2 
;MSQPTPIITTKSAAKPKPKIFNLFRVCFISLLLIAAVEYFKYGTRINYEWFHCTPIKEPQSGSVIKLWARGGPSCDKRGE
YKTIVKRITRDYEPNDEHLSFCIIENDNVPPVHYPIHEDKGEPGYVAYVGYDTDSELVQELCADSTIYHM
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8Y2N A 1 ? 418 ? P28496 1 ? 418 ? 1 418 
2 2 8Y2N B 1 ? 150 ? Q03579 1 ? 150 ? 1 150 
3 1 8Y2N C 1 ? 418 ? P28496 1 ? 418 ? 1 418 
4 2 8Y2N D 1 ? 150 ? Q03579 1 ? 150 ? 1 150 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8Y2N LEU A 419 ? UNP P28496 ? ? 'expression tag' 419 1  
1 8Y2N GLU A 420 ? UNP P28496 ? ? 'expression tag' 420 2  
1 8Y2N ASP A 421 ? UNP P28496 ? ? 'expression tag' 421 3  
1 8Y2N TYR A 422 ? UNP P28496 ? ? 'expression tag' 422 4  
1 8Y2N LYS A 423 ? UNP P28496 ? ? 'expression tag' 423 5  
1 8Y2N ASP A 424 ? UNP P28496 ? ? 'expression tag' 424 6  
1 8Y2N ASP A 425 ? UNP P28496 ? ? 'expression tag' 425 7  
1 8Y2N ASP A 426 ? UNP P28496 ? ? 'expression tag' 426 8  
1 8Y2N ASP A 427 ? UNP P28496 ? ? 'expression tag' 427 9  
1 8Y2N LYS A 428 ? UNP P28496 ? ? 'expression tag' 428 10 
3 8Y2N LEU C 419 ? UNP P28496 ? ? 'expression tag' 419 11 
3 8Y2N GLU C 420 ? UNP P28496 ? ? 'expression tag' 420 12 
3 8Y2N ASP C 421 ? UNP P28496 ? ? 'expression tag' 421 13 
3 8Y2N TYR C 422 ? UNP P28496 ? ? 'expression tag' 422 14 
3 8Y2N LYS C 423 ? UNP P28496 ? ? 'expression tag' 423 15 
3 8Y2N ASP C 424 ? UNP P28496 ? ? 'expression tag' 424 16 
3 8Y2N ASP C 425 ? UNP P28496 ? ? 'expression tag' 425 17 
3 8Y2N ASP C 426 ? UNP P28496 ? ? 'expression tag' 426 18 
3 8Y2N ASP C 427 ? UNP P28496 ? ? 'expression tag' 427 19 
3 8Y2N LYS C 428 ? UNP P28496 ? ? 'expression tag' 428 20 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ILE A 71  ? HIS A 82  ? ILE A 71  HIS A 82  1 ? 12 
HELX_P HELX_P2  AA2 TRP A 84  ? SER A 101 ? TRP A 84  SER A 101 1 ? 18 
HELX_P HELX_P3  AA3 VAL A 109 ? ALA A 115 ? VAL A 109 ALA A 115 1 ? 7  
HELX_P HELX_P4  AA4 GLY A 129 ? ILE A 160 ? GLY A 129 ILE A 160 1 ? 32 
HELX_P HELX_P5  AA5 LYS A 167 ? HIS A 196 ? LYS A 167 HIS A 196 1 ? 30 
HELX_P HELX_P6  AA6 ASN A 203 ? MET A 207 ? ASN A 203 MET A 207 5 ? 5  
HELX_P HELX_P7  AA7 PRO A 217 ? LEU A 240 ? PRO A 217 LEU A 240 1 ? 24 
HELX_P HELX_P8  AA8 ASP A 248 ? PHE A 269 ? ASP A 248 PHE A 269 1 ? 22 
HELX_P HELX_P9  AA9 GLY A 275 ? TYR A 297 ? GLY A 275 TYR A 297 1 ? 23 
HELX_P HELX_P10 AB1 GLY A 301 ? THR A 335 ? GLY A 301 THR A 335 1 ? 35 
HELX_P HELX_P11 AB2 ILE A 352 ? TRP A 384 ? ILE A 352 TRP A 384 1 ? 33 
HELX_P HELX_P12 AB3 ILE B 20  ? ASN B 47  ? ILE B 20  ASN B 47  1 ? 28 
HELX_P HELX_P13 AB4 TYR B 48  ? CYS B 53  ? TYR B 48  CYS B 53  1 ? 6  
HELX_P HELX_P14 AB5 ASP B 76  ? TYR B 92  ? ASP B 76  TYR B 92  1 ? 17 
HELX_P HELX_P15 AB6 ASP B 134 ? CYS B 142 ? ASP B 134 CYS B 142 1 ? 9  
HELX_P HELX_P16 AB7 TRP C 72  ? HIS C 82  ? TRP C 72  HIS C 82  1 ? 11 
HELX_P HELX_P17 AB8 TRP C 84  ? SER C 101 ? TRP C 84  SER C 101 1 ? 18 
HELX_P HELX_P18 AB9 VAL C 109 ? ALA C 115 ? VAL C 109 ALA C 115 1 ? 7  
HELX_P HELX_P19 AC1 GLY C 129 ? ILE C 160 ? GLY C 129 ILE C 160 1 ? 32 
HELX_P HELX_P20 AC2 LYS C 167 ? HIS C 196 ? LYS C 167 HIS C 196 1 ? 30 
HELX_P HELX_P21 AC3 ASN C 203 ? MET C 207 ? ASN C 203 MET C 207 5 ? 5  
HELX_P HELX_P22 AC4 PRO C 217 ? LEU C 240 ? PRO C 217 LEU C 240 1 ? 24 
HELX_P HELX_P23 AC5 ASP C 248 ? PHE C 269 ? ASP C 248 PHE C 269 1 ? 22 
HELX_P HELX_P24 AC6 GLY C 275 ? TYR C 297 ? GLY C 275 TYR C 297 1 ? 23 
HELX_P HELX_P25 AC7 GLY C 301 ? THR C 335 ? GLY C 301 THR C 335 1 ? 35 
HELX_P HELX_P26 AC8 ILE C 352 ? TRP C 384 ? ILE C 352 TRP C 384 1 ? 33 
HELX_P HELX_P27 AC9 ILE D 20  ? ASN D 47  ? ILE D 20  ASN D 47  1 ? 28 
HELX_P HELX_P28 AD1 TYR D 48  ? CYS D 53  ? TYR D 48  CYS D 53  1 ? 6  
HELX_P HELX_P29 AD2 ASP D 76  ? TYR D 92  ? ASP D 76  TYR D 92  1 ? 17 
HELX_P HELX_P30 AD3 ASP D 134 ? CYS D 142 ? ASP D 134 CYS D 142 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? B CYS 53  SG ? ? ? 1_555 B CYS 75  SG ? ? B CYS 53  B CYS 75  1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf2 disulf ? ? B CYS 102 SG ? ? ? 1_555 B CYS 142 SG ? ? B CYS 102 B CYS 142 1_555 ? ? ? ? ? ? ? 2.023 ? ? 
disulf3 disulf ? ? D CYS 53  SG ? ? ? 1_555 D CYS 75  SG ? ? D CYS 53  D CYS 75  1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf4 disulf ? ? D CYS 102 SG ? ? ? 1_555 D CYS 142 SG ? ? D CYS 102 D CYS 142 1_555 ? ? ? ? ? ? ? 2.023 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS B 53  ? CYS B 75  ? CYS B 53  ? 1_555 CYS B 75  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 102 ? CYS B 142 ? CYS B 102 ? 1_555 CYS B 142 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS D 53  ? CYS D 75  ? CYS D 53  ? 1_555 CYS D 75  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS D 102 ? CYS D 142 ? CYS D 102 ? 1_555 CYS D 142 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR B 54  ? PRO B 59  ? THR B 54  PRO B 59  
AA1 2 ILE B 65  ? ARG B 70  ? ILE B 65  ARG B 70  
AA1 3 TYR B 125 ? TYR B 131 ? TYR B 125 TYR B 131 
AA1 4 LEU B 99  ? GLU B 105 ? LEU B 99  GLU B 105 
AA1 5 TYR B 148 ? HIS B 149 ? TYR B 148 HIS B 149 
AA2 1 THR D 54  ? PRO D 59  ? THR D 54  PRO D 59  
AA2 2 ILE D 65  ? ARG D 70  ? ILE D 65  ARG D 70  
AA2 3 TYR D 125 ? TYR D 131 ? TYR D 125 TYR D 131 
AA2 4 LEU D 99  ? GLU D 105 ? LEU D 99  GLU D 105 
AA2 5 TYR D 148 ? HIS D 149 ? TYR D 148 HIS D 149 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE B 56  ? N ILE B 56  O TRP B 68  ? O TRP B 68  
AA1 2 3 N LEU B 67  ? N LEU B 67  O ALA B 127 ? O ALA B 127 
AA1 3 4 O VAL B 126 ? O VAL B 126 N ILE B 104 ? N ILE B 104 
AA1 4 5 N PHE B 101 ? N PHE B 101 O TYR B 148 ? O TYR B 148 
AA2 1 2 N ILE D 56  ? N ILE D 56  O TRP D 68  ? O TRP D 68  
AA2 2 3 N LEU D 67  ? N LEU D 67  O ALA D 127 ? O ALA D 127 
AA2 3 4 O VAL D 126 ? O VAL D 126 N ILE D 104 ? N ILE D 104 
AA2 4 5 N PHE D 101 ? N PHE D 101 O TYR D 148 ? O TYR D 148 
# 
_pdbx_entry_details.entry_id                   8Y2N 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O  A THR 204 ? ? N  A ALA 206 ? ? 2.00 
2 1 O  C THR 204 ? ? N  C ALA 206 ? ? 2.00 
3 1 OH A TYR 224 ? ? OG A SER 266 ? ? 2.04 
4 1 OH C TYR 224 ? ? OG C SER 266 ? ? 2.04 
5 1 O  A LEU 261 ? ? OG A SER 265 ? ? 2.09 
6 1 O  C LEU 261 ? ? OG C SER 265 ? ? 2.09 
7 1 O  A ALA 97  ? ? OG A SER 101 ? ? 2.18 
8 1 O  C ALA 97  ? ? OG C SER 101 ? ? 2.18 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CB A PHE 201 ? ? CG A PHE 201 ? ? 1.404 1.509 -0.105 0.017 N 
2 1 CB C PHE 201 ? ? CG C PHE 201 ? ? 1.404 1.509 -0.105 0.017 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR A 107 ? ? -107.11 -161.42 
2  1 ASN A 108 ? ? 84.23   -145.04 
3  1 VAL A 109 ? ? -130.56 -47.98  
4  1 HIS A 163 ? ? 87.52   141.55  
5  1 VAL A 164 ? ? -152.63 69.93   
6  1 THR A 165 ? ? -59.84  103.63  
7  1 SER A 166 ? ? -162.80 -124.55 
8  1 LYS A 167 ? ? -167.31 -77.45  
9  1 PHE A 202 ? ? 45.83   72.31   
10 1 LYS A 205 ? ? -34.59  -10.82  
11 1 ARG A 246 ? ? -55.94  -155.20 
12 1 PHE A 271 ? ? -90.65  50.70   
13 1 TRP A 384 ? ? -93.64  31.05   
14 1 ASN B 108 ? ? -88.23  46.94   
15 1 HIS B 113 ? ? -144.35 13.90   
16 1 HIS B 117 ? ? -83.20  -74.21  
17 1 GLU B 118 ? ? -146.65 -19.50  
18 1 THR C 107 ? ? -107.03 -161.37 
19 1 ASN C 108 ? ? 84.23   -145.05 
20 1 VAL C 109 ? ? -130.62 -47.98  
21 1 HIS C 163 ? ? 87.53   141.49  
22 1 VAL C 164 ? ? -152.54 69.97   
23 1 THR C 165 ? ? -59.84  103.66  
24 1 SER C 166 ? ? -162.77 -124.53 
25 1 LYS C 167 ? ? -167.30 -77.36  
26 1 PHE C 202 ? ? 45.84   72.34   
27 1 LYS C 205 ? ? -34.62  -10.79  
28 1 ASP C 213 ? ? 39.97   58.36   
29 1 ARG C 246 ? ? -56.03  -155.23 
30 1 PHE C 271 ? ? -90.62  50.67   
31 1 TRP C 384 ? ? -93.71  31.14   
32 1 ASN D 108 ? ? -88.20  46.96   
33 1 HIS D 113 ? ? -144.39 14.03   
34 1 HIS D 117 ? ? -83.20  -74.30  
35 1 GLU D 118 ? ? -146.56 -19.62  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8Y2N 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8Y2N 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.19 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               159061 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Lac1-Lip1 complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8Y2N 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8Y2N 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8Y2N 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A SER 2   ? A SER 2   
3   1 Y 1 A THR 3   ? A THR 3   
4   1 Y 1 A ILE 4   ? A ILE 4   
5   1 Y 1 A LYS 5   ? A LYS 5   
6   1 Y 1 A PRO 6   ? A PRO 6   
7   1 Y 1 A SER 7   ? A SER 7   
8   1 Y 1 A PRO 8   ? A PRO 8   
9   1 Y 1 A SER 9   ? A SER 9   
10  1 Y 1 A ASN 10  ? A ASN 10  
11  1 Y 1 A ASN 11  ? A ASN 11  
12  1 Y 1 A ASN 12  ? A ASN 12  
13  1 Y 1 A LEU 13  ? A LEU 13  
14  1 Y 1 A LYS 14  ? A LYS 14  
15  1 Y 1 A VAL 15  ? A VAL 15  
16  1 Y 1 A ARG 16  ? A ARG 16  
17  1 Y 1 A SER 17  ? A SER 17  
18  1 Y 1 A ARG 18  ? A ARG 18  
19  1 Y 1 A PRO 19  ? A PRO 19  
20  1 Y 1 A ARG 20  ? A ARG 20  
21  1 Y 1 A ARG 21  ? A ARG 21  
22  1 Y 1 A LYS 22  ? A LYS 22  
23  1 Y 1 A SER 23  ? A SER 23  
24  1 Y 1 A SER 24  ? A SER 24  
25  1 Y 1 A ILE 25  ? A ILE 25  
26  1 Y 1 A GLY 26  ? A GLY 26  
27  1 Y 1 A LYS 27  ? A LYS 27  
28  1 Y 1 A ILE 28  ? A ILE 28  
29  1 Y 1 A ASP 29  ? A ASP 29  
30  1 Y 1 A LEU 30  ? A LEU 30  
31  1 Y 1 A GLY 31  ? A GLY 31  
32  1 Y 1 A ASP 32  ? A ASP 32  
33  1 Y 1 A THR 33  ? A THR 33  
34  1 Y 1 A VAL 34  ? A VAL 34  
35  1 Y 1 A PRO 35  ? A PRO 35  
36  1 Y 1 A SER 36  ? A SER 36  
37  1 Y 1 A LEU 37  ? A LEU 37  
38  1 Y 1 A GLY 38  ? A GLY 38  
39  1 Y 1 A THR 39  ? A THR 39  
40  1 Y 1 A MET 40  ? A MET 40  
41  1 Y 1 A PHE 41  ? A PHE 41  
42  1 Y 1 A GLU 42  ? A GLU 42  
43  1 Y 1 A THR 43  ? A THR 43  
44  1 Y 1 A LYS 44  ? A LYS 44  
45  1 Y 1 A GLU 45  ? A GLU 45  
46  1 Y 1 A SER 46  ? A SER 46  
47  1 Y 1 A LYS 47  ? A LYS 47  
48  1 Y 1 A THR 48  ? A THR 48  
49  1 Y 1 A ALA 49  ? A ALA 49  
50  1 Y 1 A ALA 50  ? A ALA 50  
51  1 Y 1 A LYS 51  ? A LYS 51  
52  1 Y 1 A ARG 52  ? A ARG 52  
53  1 Y 1 A ARG 53  ? A ARG 53  
54  1 Y 1 A MET 54  ? A MET 54  
55  1 Y 1 A GLN 55  ? A GLN 55  
56  1 Y 1 A ARG 56  ? A ARG 56  
57  1 Y 1 A LEU 57  ? A LEU 57  
58  1 Y 1 A SER 58  ? A SER 58  
59  1 Y 1 A GLU 59  ? A GLU 59  
60  1 Y 1 A ALA 60  ? A ALA 60  
61  1 Y 1 A THR 61  ? A THR 61  
62  1 Y 1 A LYS 62  ? A LYS 62  
63  1 Y 1 A ASN 63  ? A ASN 63  
64  1 Y 1 A ASP 64  ? A ASP 64  
65  1 Y 1 A SER 65  ? A SER 65  
66  1 Y 1 A ASP 66  ? A ASP 66  
67  1 Y 1 A LEU 67  ? A LEU 67  
68  1 Y 1 A VAL 68  ? A VAL 68  
69  1 Y 1 A LYS 69  ? A LYS 69  
70  1 Y 1 A LYS 70  ? A LYS 70  
71  1 Y 1 A GLY 386 ? A GLY 386 
72  1 Y 1 A ILE 387 ? A ILE 387 
73  1 Y 1 A LEU 388 ? A LEU 388 
74  1 Y 1 A LYS 389 ? A LYS 389 
75  1 Y 1 A ASP 390 ? A ASP 390 
76  1 Y 1 A ASP 391 ? A ASP 391 
77  1 Y 1 A ARG 392 ? A ARG 392 
78  1 Y 1 A SER 393 ? A SER 393 
79  1 Y 1 A ASP 394 ? A ASP 394 
80  1 Y 1 A SER 395 ? A SER 395 
81  1 Y 1 A GLU 396 ? A GLU 396 
82  1 Y 1 A SER 397 ? A SER 397 
83  1 Y 1 A ASP 398 ? A ASP 398 
84  1 Y 1 A GLU 399 ? A GLU 399 
85  1 Y 1 A GLU 400 ? A GLU 400 
86  1 Y 1 A SER 401 ? A SER 401 
87  1 Y 1 A ASP 402 ? A ASP 402 
88  1 Y 1 A GLU 403 ? A GLU 403 
89  1 Y 1 A SER 404 ? A SER 404 
90  1 Y 1 A SER 405 ? A SER 405 
91  1 Y 1 A THR 406 ? A THR 406 
92  1 Y 1 A THR 407 ? A THR 407 
93  1 Y 1 A PRO 408 ? A PRO 408 
94  1 Y 1 A THR 409 ? A THR 409 
95  1 Y 1 A ASP 410 ? A ASP 410 
96  1 Y 1 A SER 411 ? A SER 411 
97  1 Y 1 A THR 412 ? A THR 412 
98  1 Y 1 A PRO 413 ? A PRO 413 
99  1 Y 1 A THR 414 ? A THR 414 
100 1 Y 1 A LYS 415 ? A LYS 415 
101 1 Y 1 A LYS 416 ? A LYS 416 
102 1 Y 1 A ASP 417 ? A ASP 417 
103 1 Y 1 A ILE 418 ? A ILE 418 
104 1 Y 1 A LEU 419 ? A LEU 419 
105 1 Y 1 A GLU 420 ? A GLU 420 
106 1 Y 1 A ASP 421 ? A ASP 421 
107 1 Y 1 A TYR 422 ? A TYR 422 
108 1 Y 1 A LYS 423 ? A LYS 423 
109 1 Y 1 A ASP 424 ? A ASP 424 
110 1 Y 1 A ASP 425 ? A ASP 425 
111 1 Y 1 A ASP 426 ? A ASP 426 
112 1 Y 1 A ASP 427 ? A ASP 427 
113 1 Y 1 A LYS 428 ? A LYS 428 
114 1 Y 1 B MET 1   ? B MET 1   
115 1 Y 1 B SER 2   ? B SER 2   
116 1 Y 1 B GLN 3   ? B GLN 3   
117 1 Y 1 B PRO 4   ? B PRO 4   
118 1 Y 1 B THR 5   ? B THR 5   
119 1 Y 1 B PRO 6   ? B PRO 6   
120 1 Y 1 B ILE 7   ? B ILE 7   
121 1 Y 1 B ILE 8   ? B ILE 8   
122 1 Y 1 B THR 9   ? B THR 9   
123 1 Y 1 B THR 10  ? B THR 10  
124 1 Y 1 B LYS 11  ? B LYS 11  
125 1 Y 1 B SER 12  ? B SER 12  
126 1 Y 1 B ALA 13  ? B ALA 13  
127 1 Y 1 B ALA 14  ? B ALA 14  
128 1 Y 1 B LYS 15  ? B LYS 15  
129 1 Y 1 B PRO 16  ? B PRO 16  
130 1 Y 1 B LYS 17  ? B LYS 17  
131 1 Y 1 C MET 1   ? C MET 1   
132 1 Y 1 C SER 2   ? C SER 2   
133 1 Y 1 C THR 3   ? C THR 3   
134 1 Y 1 C ILE 4   ? C ILE 4   
135 1 Y 1 C LYS 5   ? C LYS 5   
136 1 Y 1 C PRO 6   ? C PRO 6   
137 1 Y 1 C SER 7   ? C SER 7   
138 1 Y 1 C PRO 8   ? C PRO 8   
139 1 Y 1 C SER 9   ? C SER 9   
140 1 Y 1 C ASN 10  ? C ASN 10  
141 1 Y 1 C ASN 11  ? C ASN 11  
142 1 Y 1 C ASN 12  ? C ASN 12  
143 1 Y 1 C LEU 13  ? C LEU 13  
144 1 Y 1 C LYS 14  ? C LYS 14  
145 1 Y 1 C VAL 15  ? C VAL 15  
146 1 Y 1 C ARG 16  ? C ARG 16  
147 1 Y 1 C SER 17  ? C SER 17  
148 1 Y 1 C ARG 18  ? C ARG 18  
149 1 Y 1 C PRO 19  ? C PRO 19  
150 1 Y 1 C ARG 20  ? C ARG 20  
151 1 Y 1 C ARG 21  ? C ARG 21  
152 1 Y 1 C LYS 22  ? C LYS 22  
153 1 Y 1 C SER 23  ? C SER 23  
154 1 Y 1 C SER 24  ? C SER 24  
155 1 Y 1 C ILE 25  ? C ILE 25  
156 1 Y 1 C GLY 26  ? C GLY 26  
157 1 Y 1 C LYS 27  ? C LYS 27  
158 1 Y 1 C ILE 28  ? C ILE 28  
159 1 Y 1 C ASP 29  ? C ASP 29  
160 1 Y 1 C LEU 30  ? C LEU 30  
161 1 Y 1 C GLY 31  ? C GLY 31  
162 1 Y 1 C ASP 32  ? C ASP 32  
163 1 Y 1 C THR 33  ? C THR 33  
164 1 Y 1 C VAL 34  ? C VAL 34  
165 1 Y 1 C PRO 35  ? C PRO 35  
166 1 Y 1 C SER 36  ? C SER 36  
167 1 Y 1 C LEU 37  ? C LEU 37  
168 1 Y 1 C GLY 38  ? C GLY 38  
169 1 Y 1 C THR 39  ? C THR 39  
170 1 Y 1 C MET 40  ? C MET 40  
171 1 Y 1 C PHE 41  ? C PHE 41  
172 1 Y 1 C GLU 42  ? C GLU 42  
173 1 Y 1 C THR 43  ? C THR 43  
174 1 Y 1 C LYS 44  ? C LYS 44  
175 1 Y 1 C GLU 45  ? C GLU 45  
176 1 Y 1 C SER 46  ? C SER 46  
177 1 Y 1 C LYS 47  ? C LYS 47  
178 1 Y 1 C THR 48  ? C THR 48  
179 1 Y 1 C ALA 49  ? C ALA 49  
180 1 Y 1 C ALA 50  ? C ALA 50  
181 1 Y 1 C LYS 51  ? C LYS 51  
182 1 Y 1 C ARG 52  ? C ARG 52  
183 1 Y 1 C ARG 53  ? C ARG 53  
184 1 Y 1 C MET 54  ? C MET 54  
185 1 Y 1 C GLN 55  ? C GLN 55  
186 1 Y 1 C ARG 56  ? C ARG 56  
187 1 Y 1 C LEU 57  ? C LEU 57  
188 1 Y 1 C SER 58  ? C SER 58  
189 1 Y 1 C GLU 59  ? C GLU 59  
190 1 Y 1 C ALA 60  ? C ALA 60  
191 1 Y 1 C THR 61  ? C THR 61  
192 1 Y 1 C LYS 62  ? C LYS 62  
193 1 Y 1 C ASN 63  ? C ASN 63  
194 1 Y 1 C ASP 64  ? C ASP 64  
195 1 Y 1 C SER 65  ? C SER 65  
196 1 Y 1 C ASP 66  ? C ASP 66  
197 1 Y 1 C LEU 67  ? C LEU 67  
198 1 Y 1 C VAL 68  ? C VAL 68  
199 1 Y 1 C LYS 69  ? C LYS 69  
200 1 Y 1 C LYS 70  ? C LYS 70  
201 1 Y 1 C GLY 386 ? C GLY 386 
202 1 Y 1 C ILE 387 ? C ILE 387 
203 1 Y 1 C LEU 388 ? C LEU 388 
204 1 Y 1 C LYS 389 ? C LYS 389 
205 1 Y 1 C ASP 390 ? C ASP 390 
206 1 Y 1 C ASP 391 ? C ASP 391 
207 1 Y 1 C ARG 392 ? C ARG 392 
208 1 Y 1 C SER 393 ? C SER 393 
209 1 Y 1 C ASP 394 ? C ASP 394 
210 1 Y 1 C SER 395 ? C SER 395 
211 1 Y 1 C GLU 396 ? C GLU 396 
212 1 Y 1 C SER 397 ? C SER 397 
213 1 Y 1 C ASP 398 ? C ASP 398 
214 1 Y 1 C GLU 399 ? C GLU 399 
215 1 Y 1 C GLU 400 ? C GLU 400 
216 1 Y 1 C SER 401 ? C SER 401 
217 1 Y 1 C ASP 402 ? C ASP 402 
218 1 Y 1 C GLU 403 ? C GLU 403 
219 1 Y 1 C SER 404 ? C SER 404 
220 1 Y 1 C SER 405 ? C SER 405 
221 1 Y 1 C THR 406 ? C THR 406 
222 1 Y 1 C THR 407 ? C THR 407 
223 1 Y 1 C PRO 408 ? C PRO 408 
224 1 Y 1 C THR 409 ? C THR 409 
225 1 Y 1 C ASP 410 ? C ASP 410 
226 1 Y 1 C SER 411 ? C SER 411 
227 1 Y 1 C THR 412 ? C THR 412 
228 1 Y 1 C PRO 413 ? C PRO 413 
229 1 Y 1 C THR 414 ? C THR 414 
230 1 Y 1 C LYS 415 ? C LYS 415 
231 1 Y 1 C LYS 416 ? C LYS 416 
232 1 Y 1 C ASP 417 ? C ASP 417 
233 1 Y 1 C ILE 418 ? C ILE 418 
234 1 Y 1 C LEU 419 ? C LEU 419 
235 1 Y 1 C GLU 420 ? C GLU 420 
236 1 Y 1 C ASP 421 ? C ASP 421 
237 1 Y 1 C TYR 422 ? C TYR 422 
238 1 Y 1 C LYS 423 ? C LYS 423 
239 1 Y 1 C ASP 424 ? C ASP 424 
240 1 Y 1 C ASP 425 ? C ASP 425 
241 1 Y 1 C ASP 426 ? C ASP 426 
242 1 Y 1 C ASP 427 ? C ASP 427 
243 1 Y 1 C LYS 428 ? C LYS 428 
244 1 Y 1 D MET 1   ? D MET 1   
245 1 Y 1 D SER 2   ? D SER 2   
246 1 Y 1 D GLN 3   ? D GLN 3   
247 1 Y 1 D PRO 4   ? D PRO 4   
248 1 Y 1 D THR 5   ? D THR 5   
249 1 Y 1 D PRO 6   ? D PRO 6   
250 1 Y 1 D ILE 7   ? D ILE 7   
251 1 Y 1 D ILE 8   ? D ILE 8   
252 1 Y 1 D THR 9   ? D THR 9   
253 1 Y 1 D THR 10  ? D THR 10  
254 1 Y 1 D LYS 11  ? D LYS 11  
255 1 Y 1 D SER 12  ? D SER 12  
256 1 Y 1 D ALA 13  ? D ALA 13  
257 1 Y 1 D ALA 14  ? D ALA 14  
258 1 Y 1 D LYS 15  ? D LYS 15  
259 1 Y 1 D PRO 16  ? D PRO 16  
260 1 Y 1 D LYS 17  ? D LYS 17  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
6PL C26  C N N 1   
6PL C25  C N N 2   
6PL C24  C N N 3   
6PL C23  C N N 4   
6PL C22  C N N 5   
6PL C21  C N N 6   
6PL C20  C N N 7   
6PL C19  C N N 8   
6PL C18  C N N 9   
6PL C17  C N N 10  
6PL C16  C N N 11  
6PL C15  C N N 12  
6PL C14  C N N 13  
6PL C13  C N N 14  
6PL C12  C N N 15  
6PL C11  C N N 16  
6PL O11  O N N 17  
6PL O3   O N N 18  
6PL C3   C N N 19  
6PL C2   C N R 20  
6PL C1   C N N 21  
6PL O3P  O N N 22  
6PL P    P N S 23  
6PL O1P  O N N 24  
6PL O2P  O N N 25  
6PL O4P  O N N 26  
6PL C4   C N N 27  
6PL C5   C N N 28  
6PL N    N N N 29  
6PL C7   C N N 30  
6PL C8   C N N 31  
6PL C6   C N N 32  
6PL O2   O N N 33  
6PL C31  C N N 34  
6PL O31  O N N 35  
6PL C32  C N N 36  
6PL C33  C N N 37  
6PL C34  C N N 38  
6PL C35  C N N 39  
6PL C36  C N N 40  
6PL C37  C N N 41  
6PL C38  C N N 42  
6PL C39  C N N 43  
6PL C40  C N N 44  
6PL C41  C N N 45  
6PL C42  C N N 46  
6PL C43  C N N 47  
6PL C44  C N N 48  
6PL C45  C N N 49  
6PL C46  C N N 50  
6PL C47  C N N 51  
6PL C48  C N N 52  
6PL H261 H N N 53  
6PL H262 H N N 54  
6PL H263 H N N 55  
6PL H251 H N N 56  
6PL H252 H N N 57  
6PL H241 H N N 58  
6PL H242 H N N 59  
6PL H231 H N N 60  
6PL H232 H N N 61  
6PL H221 H N N 62  
6PL H222 H N N 63  
6PL H211 H N N 64  
6PL H212 H N N 65  
6PL H201 H N N 66  
6PL H202 H N N 67  
6PL H191 H N N 68  
6PL H192 H N N 69  
6PL H181 H N N 70  
6PL H182 H N N 71  
6PL H171 H N N 72  
6PL H172 H N N 73  
6PL H161 H N N 74  
6PL H162 H N N 75  
6PL H151 H N N 76  
6PL H152 H N N 77  
6PL H141 H N N 78  
6PL H142 H N N 79  
6PL H131 H N N 80  
6PL H132 H N N 81  
6PL H121 H N N 82  
6PL H122 H N N 83  
6PL H31  H N N 84  
6PL H32  H N N 85  
6PL H2   H N N 86  
6PL H11  H N N 87  
6PL H12  H N N 88  
6PL H2P  H N N 89  
6PL H41  H N N 90  
6PL H42  H N N 91  
6PL H51  H N N 92  
6PL H52  H N N 93  
6PL H71  H N N 94  
6PL H72  H N N 95  
6PL H73  H N N 96  
6PL H81  H N N 97  
6PL H82  H N N 98  
6PL H83  H N N 99  
6PL H61  H N N 100 
6PL H62  H N N 101 
6PL H63  H N N 102 
6PL H321 H N N 103 
6PL H322 H N N 104 
6PL H331 H N N 105 
6PL H332 H N N 106 
6PL H341 H N N 107 
6PL H342 H N N 108 
6PL H351 H N N 109 
6PL H352 H N N 110 
6PL H361 H N N 111 
6PL H362 H N N 112 
6PL H371 H N N 113 
6PL H372 H N N 114 
6PL H381 H N N 115 
6PL H382 H N N 116 
6PL H391 H N N 117 
6PL H392 H N N 118 
6PL H401 H N N 119 
6PL H402 H N N 120 
6PL H411 H N N 121 
6PL H412 H N N 122 
6PL H421 H N N 123 
6PL H422 H N N 124 
6PL H431 H N N 125 
6PL H432 H N N 126 
6PL H441 H N N 127 
6PL H442 H N N 128 
6PL H451 H N N 129 
6PL H452 H N N 130 
6PL H461 H N N 131 
6PL H462 H N N 132 
6PL H471 H N N 133 
6PL H472 H N N 134 
6PL H481 H N N 135 
6PL H482 H N N 136 
6PL H483 H N N 137 
ALA N    N N N 138 
ALA CA   C N S 139 
ALA C    C N N 140 
ALA O    O N N 141 
ALA CB   C N N 142 
ALA OXT  O N N 143 
ALA H    H N N 144 
ALA H2   H N N 145 
ALA HA   H N N 146 
ALA HB1  H N N 147 
ALA HB2  H N N 148 
ALA HB3  H N N 149 
ALA HXT  H N N 150 
ARG N    N N N 151 
ARG CA   C N S 152 
ARG C    C N N 153 
ARG O    O N N 154 
ARG CB   C N N 155 
ARG CG   C N N 156 
ARG CD   C N N 157 
ARG NE   N N N 158 
ARG CZ   C N N 159 
ARG NH1  N N N 160 
ARG NH2  N N N 161 
ARG OXT  O N N 162 
ARG H    H N N 163 
ARG H2   H N N 164 
ARG HA   H N N 165 
ARG HB2  H N N 166 
ARG HB3  H N N 167 
ARG HG2  H N N 168 
ARG HG3  H N N 169 
ARG HD2  H N N 170 
ARG HD3  H N N 171 
ARG HE   H N N 172 
ARG HH11 H N N 173 
ARG HH12 H N N 174 
ARG HH21 H N N 175 
ARG HH22 H N N 176 
ARG HXT  H N N 177 
ASN N    N N N 178 
ASN CA   C N S 179 
ASN C    C N N 180 
ASN O    O N N 181 
ASN CB   C N N 182 
ASN CG   C N N 183 
ASN OD1  O N N 184 
ASN ND2  N N N 185 
ASN OXT  O N N 186 
ASN H    H N N 187 
ASN H2   H N N 188 
ASN HA   H N N 189 
ASN HB2  H N N 190 
ASN HB3  H N N 191 
ASN HD21 H N N 192 
ASN HD22 H N N 193 
ASN HXT  H N N 194 
ASP N    N N N 195 
ASP CA   C N S 196 
ASP C    C N N 197 
ASP O    O N N 198 
ASP CB   C N N 199 
ASP CG   C N N 200 
ASP OD1  O N N 201 
ASP OD2  O N N 202 
ASP OXT  O N N 203 
ASP H    H N N 204 
ASP H2   H N N 205 
ASP HA   H N N 206 
ASP HB2  H N N 207 
ASP HB3  H N N 208 
ASP HD2  H N N 209 
ASP HXT  H N N 210 
CYS N    N N N 211 
CYS CA   C N R 212 
CYS C    C N N 213 
CYS O    O N N 214 
CYS CB   C N N 215 
CYS SG   S N N 216 
CYS OXT  O N N 217 
CYS H    H N N 218 
CYS H2   H N N 219 
CYS HA   H N N 220 
CYS HB2  H N N 221 
CYS HB3  H N N 222 
CYS HG   H N N 223 
CYS HXT  H N N 224 
GLN N    N N N 225 
GLN CA   C N S 226 
GLN C    C N N 227 
GLN O    O N N 228 
GLN CB   C N N 229 
GLN CG   C N N 230 
GLN CD   C N N 231 
GLN OE1  O N N 232 
GLN NE2  N N N 233 
GLN OXT  O N N 234 
GLN H    H N N 235 
GLN H2   H N N 236 
GLN HA   H N N 237 
GLN HB2  H N N 238 
GLN HB3  H N N 239 
GLN HG2  H N N 240 
GLN HG3  H N N 241 
GLN HE21 H N N 242 
GLN HE22 H N N 243 
GLN HXT  H N N 244 
GLU N    N N N 245 
GLU CA   C N S 246 
GLU C    C N N 247 
GLU O    O N N 248 
GLU CB   C N N 249 
GLU CG   C N N 250 
GLU CD   C N N 251 
GLU OE1  O N N 252 
GLU OE2  O N N 253 
GLU OXT  O N N 254 
GLU H    H N N 255 
GLU H2   H N N 256 
GLU HA   H N N 257 
GLU HB2  H N N 258 
GLU HB3  H N N 259 
GLU HG2  H N N 260 
GLU HG3  H N N 261 
GLU HE2  H N N 262 
GLU HXT  H N N 263 
GLY N    N N N 264 
GLY CA   C N N 265 
GLY C    C N N 266 
GLY O    O N N 267 
GLY OXT  O N N 268 
GLY H    H N N 269 
GLY H2   H N N 270 
GLY HA2  H N N 271 
GLY HA3  H N N 272 
GLY HXT  H N N 273 
HIS N    N N N 274 
HIS CA   C N S 275 
HIS C    C N N 276 
HIS O    O N N 277 
HIS CB   C N N 278 
HIS CG   C Y N 279 
HIS ND1  N Y N 280 
HIS CD2  C Y N 281 
HIS CE1  C Y N 282 
HIS NE2  N Y N 283 
HIS OXT  O N N 284 
HIS H    H N N 285 
HIS H2   H N N 286 
HIS HA   H N N 287 
HIS HB2  H N N 288 
HIS HB3  H N N 289 
HIS HD1  H N N 290 
HIS HD2  H N N 291 
HIS HE1  H N N 292 
HIS HE2  H N N 293 
HIS HXT  H N N 294 
ILE N    N N N 295 
ILE CA   C N S 296 
ILE C    C N N 297 
ILE O    O N N 298 
ILE CB   C N S 299 
ILE CG1  C N N 300 
ILE CG2  C N N 301 
ILE CD1  C N N 302 
ILE OXT  O N N 303 
ILE H    H N N 304 
ILE H2   H N N 305 
ILE HA   H N N 306 
ILE HB   H N N 307 
ILE HG12 H N N 308 
ILE HG13 H N N 309 
ILE HG21 H N N 310 
ILE HG22 H N N 311 
ILE HG23 H N N 312 
ILE HD11 H N N 313 
ILE HD12 H N N 314 
ILE HD13 H N N 315 
ILE HXT  H N N 316 
LEU N    N N N 317 
LEU CA   C N S 318 
LEU C    C N N 319 
LEU O    O N N 320 
LEU CB   C N N 321 
LEU CG   C N N 322 
LEU CD1  C N N 323 
LEU CD2  C N N 324 
LEU OXT  O N N 325 
LEU H    H N N 326 
LEU H2   H N N 327 
LEU HA   H N N 328 
LEU HB2  H N N 329 
LEU HB3  H N N 330 
LEU HG   H N N 331 
LEU HD11 H N N 332 
LEU HD12 H N N 333 
LEU HD13 H N N 334 
LEU HD21 H N N 335 
LEU HD22 H N N 336 
LEU HD23 H N N 337 
LEU HXT  H N N 338 
LYS N    N N N 339 
LYS CA   C N S 340 
LYS C    C N N 341 
LYS O    O N N 342 
LYS CB   C N N 343 
LYS CG   C N N 344 
LYS CD   C N N 345 
LYS CE   C N N 346 
LYS NZ   N N N 347 
LYS OXT  O N N 348 
LYS H    H N N 349 
LYS H2   H N N 350 
LYS HA   H N N 351 
LYS HB2  H N N 352 
LYS HB3  H N N 353 
LYS HG2  H N N 354 
LYS HG3  H N N 355 
LYS HD2  H N N 356 
LYS HD3  H N N 357 
LYS HE2  H N N 358 
LYS HE3  H N N 359 
LYS HZ1  H N N 360 
LYS HZ2  H N N 361 
LYS HZ3  H N N 362 
LYS HXT  H N N 363 
MET N    N N N 364 
MET CA   C N S 365 
MET C    C N N 366 
MET O    O N N 367 
MET CB   C N N 368 
MET CG   C N N 369 
MET SD   S N N 370 
MET CE   C N N 371 
MET OXT  O N N 372 
MET H    H N N 373 
MET H2   H N N 374 
MET HA   H N N 375 
MET HB2  H N N 376 
MET HB3  H N N 377 
MET HG2  H N N 378 
MET HG3  H N N 379 
MET HE1  H N N 380 
MET HE2  H N N 381 
MET HE3  H N N 382 
MET HXT  H N N 383 
PHE N    N N N 384 
PHE CA   C N S 385 
PHE C    C N N 386 
PHE O    O N N 387 
PHE CB   C N N 388 
PHE CG   C Y N 389 
PHE CD1  C Y N 390 
PHE CD2  C Y N 391 
PHE CE1  C Y N 392 
PHE CE2  C Y N 393 
PHE CZ   C Y N 394 
PHE OXT  O N N 395 
PHE H    H N N 396 
PHE H2   H N N 397 
PHE HA   H N N 398 
PHE HB2  H N N 399 
PHE HB3  H N N 400 
PHE HD1  H N N 401 
PHE HD2  H N N 402 
PHE HE1  H N N 403 
PHE HE2  H N N 404 
PHE HZ   H N N 405 
PHE HXT  H N N 406 
PRO N    N N N 407 
PRO CA   C N S 408 
PRO C    C N N 409 
PRO O    O N N 410 
PRO CB   C N N 411 
PRO CG   C N N 412 
PRO CD   C N N 413 
PRO OXT  O N N 414 
PRO H    H N N 415 
PRO HA   H N N 416 
PRO HB2  H N N 417 
PRO HB3  H N N 418 
PRO HG2  H N N 419 
PRO HG3  H N N 420 
PRO HD2  H N N 421 
PRO HD3  H N N 422 
PRO HXT  H N N 423 
SER N    N N N 424 
SER CA   C N S 425 
SER C    C N N 426 
SER O    O N N 427 
SER CB   C N N 428 
SER OG   O N N 429 
SER OXT  O N N 430 
SER H    H N N 431 
SER H2   H N N 432 
SER HA   H N N 433 
SER HB2  H N N 434 
SER HB3  H N N 435 
SER HG   H N N 436 
SER HXT  H N N 437 
THR N    N N N 438 
THR CA   C N S 439 
THR C    C N N 440 
THR O    O N N 441 
THR CB   C N R 442 
THR OG1  O N N 443 
THR CG2  C N N 444 
THR OXT  O N N 445 
THR H    H N N 446 
THR H2   H N N 447 
THR HA   H N N 448 
THR HB   H N N 449 
THR HG1  H N N 450 
THR HG21 H N N 451 
THR HG22 H N N 452 
THR HG23 H N N 453 
THR HXT  H N N 454 
TRP N    N N N 455 
TRP CA   C N S 456 
TRP C    C N N 457 
TRP O    O N N 458 
TRP CB   C N N 459 
TRP CG   C Y N 460 
TRP CD1  C Y N 461 
TRP CD2  C Y N 462 
TRP NE1  N Y N 463 
TRP CE2  C Y N 464 
TRP CE3  C Y N 465 
TRP CZ2  C Y N 466 
TRP CZ3  C Y N 467 
TRP CH2  C Y N 468 
TRP OXT  O N N 469 
TRP H    H N N 470 
TRP H2   H N N 471 
TRP HA   H N N 472 
TRP HB2  H N N 473 
TRP HB3  H N N 474 
TRP HD1  H N N 475 
TRP HE1  H N N 476 
TRP HE3  H N N 477 
TRP HZ2  H N N 478 
TRP HZ3  H N N 479 
TRP HH2  H N N 480 
TRP HXT  H N N 481 
TYR N    N N N 482 
TYR CA   C N S 483 
TYR C    C N N 484 
TYR O    O N N 485 
TYR CB   C N N 486 
TYR CG   C Y N 487 
TYR CD1  C Y N 488 
TYR CD2  C Y N 489 
TYR CE1  C Y N 490 
TYR CE2  C Y N 491 
TYR CZ   C Y N 492 
TYR OH   O N N 493 
TYR OXT  O N N 494 
TYR H    H N N 495 
TYR H2   H N N 496 
TYR HA   H N N 497 
TYR HB2  H N N 498 
TYR HB3  H N N 499 
TYR HD1  H N N 500 
TYR HD2  H N N 501 
TYR HE1  H N N 502 
TYR HE2  H N N 503 
TYR HH   H N N 504 
TYR HXT  H N N 505 
VAL N    N N N 506 
VAL CA   C N S 507 
VAL C    C N N 508 
VAL O    O N N 509 
VAL CB   C N N 510 
VAL CG1  C N N 511 
VAL CG2  C N N 512 
VAL OXT  O N N 513 
VAL H    H N N 514 
VAL H2   H N N 515 
VAL HA   H N N 516 
VAL HB   H N N 517 
VAL HG11 H N N 518 
VAL HG12 H N N 519 
VAL HG13 H N N 520 
VAL HG21 H N N 521 
VAL HG22 H N N 522 
VAL HG23 H N N 523 
VAL HXT  H N N 524 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
6PL C26 C25  sing N N 1   
6PL C26 H261 sing N N 2   
6PL C26 H262 sing N N 3   
6PL C26 H263 sing N N 4   
6PL C25 C24  sing N N 5   
6PL C25 H251 sing N N 6   
6PL C25 H252 sing N N 7   
6PL C24 C23  sing N N 8   
6PL C24 H241 sing N N 9   
6PL C24 H242 sing N N 10  
6PL C23 C22  sing N N 11  
6PL C23 H231 sing N N 12  
6PL C23 H232 sing N N 13  
6PL C22 C21  sing N N 14  
6PL C22 H221 sing N N 15  
6PL C22 H222 sing N N 16  
6PL C21 C20  sing N N 17  
6PL C21 H211 sing N N 18  
6PL C21 H212 sing N N 19  
6PL C20 C19  sing N N 20  
6PL C20 H201 sing N N 21  
6PL C20 H202 sing N N 22  
6PL C19 C18  sing N N 23  
6PL C19 H191 sing N N 24  
6PL C19 H192 sing N N 25  
6PL C18 C17  sing N N 26  
6PL C18 H181 sing N N 27  
6PL C18 H182 sing N N 28  
6PL C17 C16  sing N N 29  
6PL C17 H171 sing N N 30  
6PL C17 H172 sing N N 31  
6PL C16 C15  sing N N 32  
6PL C16 H161 sing N N 33  
6PL C16 H162 sing N N 34  
6PL C15 C14  sing N N 35  
6PL C15 H151 sing N N 36  
6PL C15 H152 sing N N 37  
6PL C14 C13  sing N N 38  
6PL C14 H141 sing N N 39  
6PL C14 H142 sing N N 40  
6PL C13 C12  sing N N 41  
6PL C13 H131 sing N N 42  
6PL C13 H132 sing N N 43  
6PL C12 C11  sing N N 44  
6PL C12 H121 sing N N 45  
6PL C12 H122 sing N N 46  
6PL C11 O11  doub N N 47  
6PL C11 O3   sing N N 48  
6PL O3  C3   sing N N 49  
6PL C3  C2   sing N N 50  
6PL C3  H31  sing N N 51  
6PL C3  H32  sing N N 52  
6PL C2  C1   sing N N 53  
6PL C2  O2   sing N N 54  
6PL C2  H2   sing N N 55  
6PL C1  O3P  sing N N 56  
6PL C1  H11  sing N N 57  
6PL C1  H12  sing N N 58  
6PL O3P P    sing N N 59  
6PL P   O1P  doub N N 60  
6PL P   O2P  sing N N 61  
6PL P   O4P  sing N N 62  
6PL O2P H2P  sing N N 63  
6PL O4P C4   sing N N 64  
6PL C4  C5   sing N N 65  
6PL C4  H41  sing N N 66  
6PL C4  H42  sing N N 67  
6PL C5  N    sing N N 68  
6PL C5  H51  sing N N 69  
6PL C5  H52  sing N N 70  
6PL N   C7   sing N N 71  
6PL N   C8   sing N N 72  
6PL N   C6   sing N N 73  
6PL C7  H71  sing N N 74  
6PL C7  H72  sing N N 75  
6PL C7  H73  sing N N 76  
6PL C8  H81  sing N N 77  
6PL C8  H82  sing N N 78  
6PL C8  H83  sing N N 79  
6PL C6  H61  sing N N 80  
6PL C6  H62  sing N N 81  
6PL C6  H63  sing N N 82  
6PL O2  C31  sing N N 83  
6PL C31 O31  doub N N 84  
6PL C31 C32  sing N N 85  
6PL C32 C33  sing N N 86  
6PL C32 H321 sing N N 87  
6PL C32 H322 sing N N 88  
6PL C33 C34  sing N N 89  
6PL C33 H331 sing N N 90  
6PL C33 H332 sing N N 91  
6PL C34 C35  sing N N 92  
6PL C34 H341 sing N N 93  
6PL C34 H342 sing N N 94  
6PL C35 C36  sing N N 95  
6PL C35 H351 sing N N 96  
6PL C35 H352 sing N N 97  
6PL C36 C37  sing N N 98  
6PL C36 H361 sing N N 99  
6PL C36 H362 sing N N 100 
6PL C37 C38  sing N N 101 
6PL C37 H371 sing N N 102 
6PL C37 H372 sing N N 103 
6PL C38 C39  sing N N 104 
6PL C38 H381 sing N N 105 
6PL C38 H382 sing N N 106 
6PL C39 C40  sing N N 107 
6PL C39 H391 sing N N 108 
6PL C39 H392 sing N N 109 
6PL C40 C41  sing N N 110 
6PL C40 H401 sing N N 111 
6PL C40 H402 sing N N 112 
6PL C41 C42  sing N N 113 
6PL C41 H411 sing N N 114 
6PL C41 H412 sing N N 115 
6PL C42 C43  sing N N 116 
6PL C42 H421 sing N N 117 
6PL C42 H422 sing N N 118 
6PL C43 C44  sing N N 119 
6PL C43 H431 sing N N 120 
6PL C43 H432 sing N N 121 
6PL C44 C45  sing N N 122 
6PL C44 H441 sing N N 123 
6PL C44 H442 sing N N 124 
6PL C45 C46  sing N N 125 
6PL C45 H451 sing N N 126 
6PL C45 H452 sing N N 127 
6PL C46 C47  sing N N 128 
6PL C46 H461 sing N N 129 
6PL C46 H462 sing N N 130 
6PL C47 C48  sing N N 131 
6PL C47 H471 sing N N 132 
6PL C47 H472 sing N N 133 
6PL C48 H481 sing N N 134 
6PL C48 H482 sing N N 135 
6PL C48 H483 sing N N 136 
ALA N   CA   sing N N 137 
ALA N   H    sing N N 138 
ALA N   H2   sing N N 139 
ALA CA  C    sing N N 140 
ALA CA  CB   sing N N 141 
ALA CA  HA   sing N N 142 
ALA C   O    doub N N 143 
ALA C   OXT  sing N N 144 
ALA CB  HB1  sing N N 145 
ALA CB  HB2  sing N N 146 
ALA CB  HB3  sing N N 147 
ALA OXT HXT  sing N N 148 
ARG N   CA   sing N N 149 
ARG N   H    sing N N 150 
ARG N   H2   sing N N 151 
ARG CA  C    sing N N 152 
ARG CA  CB   sing N N 153 
ARG CA  HA   sing N N 154 
ARG C   O    doub N N 155 
ARG C   OXT  sing N N 156 
ARG CB  CG   sing N N 157 
ARG CB  HB2  sing N N 158 
ARG CB  HB3  sing N N 159 
ARG CG  CD   sing N N 160 
ARG CG  HG2  sing N N 161 
ARG CG  HG3  sing N N 162 
ARG CD  NE   sing N N 163 
ARG CD  HD2  sing N N 164 
ARG CD  HD3  sing N N 165 
ARG NE  CZ   sing N N 166 
ARG NE  HE   sing N N 167 
ARG CZ  NH1  sing N N 168 
ARG CZ  NH2  doub N N 169 
ARG NH1 HH11 sing N N 170 
ARG NH1 HH12 sing N N 171 
ARG NH2 HH21 sing N N 172 
ARG NH2 HH22 sing N N 173 
ARG OXT HXT  sing N N 174 
ASN N   CA   sing N N 175 
ASN N   H    sing N N 176 
ASN N   H2   sing N N 177 
ASN CA  C    sing N N 178 
ASN CA  CB   sing N N 179 
ASN CA  HA   sing N N 180 
ASN C   O    doub N N 181 
ASN C   OXT  sing N N 182 
ASN CB  CG   sing N N 183 
ASN CB  HB2  sing N N 184 
ASN CB  HB3  sing N N 185 
ASN CG  OD1  doub N N 186 
ASN CG  ND2  sing N N 187 
ASN ND2 HD21 sing N N 188 
ASN ND2 HD22 sing N N 189 
ASN OXT HXT  sing N N 190 
ASP N   CA   sing N N 191 
ASP N   H    sing N N 192 
ASP N   H2   sing N N 193 
ASP CA  C    sing N N 194 
ASP CA  CB   sing N N 195 
ASP CA  HA   sing N N 196 
ASP C   O    doub N N 197 
ASP C   OXT  sing N N 198 
ASP CB  CG   sing N N 199 
ASP CB  HB2  sing N N 200 
ASP CB  HB3  sing N N 201 
ASP CG  OD1  doub N N 202 
ASP CG  OD2  sing N N 203 
ASP OD2 HD2  sing N N 204 
ASP OXT HXT  sing N N 205 
CYS N   CA   sing N N 206 
CYS N   H    sing N N 207 
CYS N   H2   sing N N 208 
CYS CA  C    sing N N 209 
CYS CA  CB   sing N N 210 
CYS CA  HA   sing N N 211 
CYS C   O    doub N N 212 
CYS C   OXT  sing N N 213 
CYS CB  SG   sing N N 214 
CYS CB  HB2  sing N N 215 
CYS CB  HB3  sing N N 216 
CYS SG  HG   sing N N 217 
CYS OXT HXT  sing N N 218 
GLN N   CA   sing N N 219 
GLN N   H    sing N N 220 
GLN N   H2   sing N N 221 
GLN CA  C    sing N N 222 
GLN CA  CB   sing N N 223 
GLN CA  HA   sing N N 224 
GLN C   O    doub N N 225 
GLN C   OXT  sing N N 226 
GLN CB  CG   sing N N 227 
GLN CB  HB2  sing N N 228 
GLN CB  HB3  sing N N 229 
GLN CG  CD   sing N N 230 
GLN CG  HG2  sing N N 231 
GLN CG  HG3  sing N N 232 
GLN CD  OE1  doub N N 233 
GLN CD  NE2  sing N N 234 
GLN NE2 HE21 sing N N 235 
GLN NE2 HE22 sing N N 236 
GLN OXT HXT  sing N N 237 
GLU N   CA   sing N N 238 
GLU N   H    sing N N 239 
GLU N   H2   sing N N 240 
GLU CA  C    sing N N 241 
GLU CA  CB   sing N N 242 
GLU CA  HA   sing N N 243 
GLU C   O    doub N N 244 
GLU C   OXT  sing N N 245 
GLU CB  CG   sing N N 246 
GLU CB  HB2  sing N N 247 
GLU CB  HB3  sing N N 248 
GLU CG  CD   sing N N 249 
GLU CG  HG2  sing N N 250 
GLU CG  HG3  sing N N 251 
GLU CD  OE1  doub N N 252 
GLU CD  OE2  sing N N 253 
GLU OE2 HE2  sing N N 254 
GLU OXT HXT  sing N N 255 
GLY N   CA   sing N N 256 
GLY N   H    sing N N 257 
GLY N   H2   sing N N 258 
GLY CA  C    sing N N 259 
GLY CA  HA2  sing N N 260 
GLY CA  HA3  sing N N 261 
GLY C   O    doub N N 262 
GLY C   OXT  sing N N 263 
GLY OXT HXT  sing N N 264 
HIS N   CA   sing N N 265 
HIS N   H    sing N N 266 
HIS N   H2   sing N N 267 
HIS CA  C    sing N N 268 
HIS CA  CB   sing N N 269 
HIS CA  HA   sing N N 270 
HIS C   O    doub N N 271 
HIS C   OXT  sing N N 272 
HIS CB  CG   sing N N 273 
HIS CB  HB2  sing N N 274 
HIS CB  HB3  sing N N 275 
HIS CG  ND1  sing Y N 276 
HIS CG  CD2  doub Y N 277 
HIS ND1 CE1  doub Y N 278 
HIS ND1 HD1  sing N N 279 
HIS CD2 NE2  sing Y N 280 
HIS CD2 HD2  sing N N 281 
HIS CE1 NE2  sing Y N 282 
HIS CE1 HE1  sing N N 283 
HIS NE2 HE2  sing N N 284 
HIS OXT HXT  sing N N 285 
ILE N   CA   sing N N 286 
ILE N   H    sing N N 287 
ILE N   H2   sing N N 288 
ILE CA  C    sing N N 289 
ILE CA  CB   sing N N 290 
ILE CA  HA   sing N N 291 
ILE C   O    doub N N 292 
ILE C   OXT  sing N N 293 
ILE CB  CG1  sing N N 294 
ILE CB  CG2  sing N N 295 
ILE CB  HB   sing N N 296 
ILE CG1 CD1  sing N N 297 
ILE CG1 HG12 sing N N 298 
ILE CG1 HG13 sing N N 299 
ILE CG2 HG21 sing N N 300 
ILE CG2 HG22 sing N N 301 
ILE CG2 HG23 sing N N 302 
ILE CD1 HD11 sing N N 303 
ILE CD1 HD12 sing N N 304 
ILE CD1 HD13 sing N N 305 
ILE OXT HXT  sing N N 306 
LEU N   CA   sing N N 307 
LEU N   H    sing N N 308 
LEU N   H2   sing N N 309 
LEU CA  C    sing N N 310 
LEU CA  CB   sing N N 311 
LEU CA  HA   sing N N 312 
LEU C   O    doub N N 313 
LEU C   OXT  sing N N 314 
LEU CB  CG   sing N N 315 
LEU CB  HB2  sing N N 316 
LEU CB  HB3  sing N N 317 
LEU CG  CD1  sing N N 318 
LEU CG  CD2  sing N N 319 
LEU CG  HG   sing N N 320 
LEU CD1 HD11 sing N N 321 
LEU CD1 HD12 sing N N 322 
LEU CD1 HD13 sing N N 323 
LEU CD2 HD21 sing N N 324 
LEU CD2 HD22 sing N N 325 
LEU CD2 HD23 sing N N 326 
LEU OXT HXT  sing N N 327 
LYS N   CA   sing N N 328 
LYS N   H    sing N N 329 
LYS N   H2   sing N N 330 
LYS CA  C    sing N N 331 
LYS CA  CB   sing N N 332 
LYS CA  HA   sing N N 333 
LYS C   O    doub N N 334 
LYS C   OXT  sing N N 335 
LYS CB  CG   sing N N 336 
LYS CB  HB2  sing N N 337 
LYS CB  HB3  sing N N 338 
LYS CG  CD   sing N N 339 
LYS CG  HG2  sing N N 340 
LYS CG  HG3  sing N N 341 
LYS CD  CE   sing N N 342 
LYS CD  HD2  sing N N 343 
LYS CD  HD3  sing N N 344 
LYS CE  NZ   sing N N 345 
LYS CE  HE2  sing N N 346 
LYS CE  HE3  sing N N 347 
LYS NZ  HZ1  sing N N 348 
LYS NZ  HZ2  sing N N 349 
LYS NZ  HZ3  sing N N 350 
LYS OXT HXT  sing N N 351 
MET N   CA   sing N N 352 
MET N   H    sing N N 353 
MET N   H2   sing N N 354 
MET CA  C    sing N N 355 
MET CA  CB   sing N N 356 
MET CA  HA   sing N N 357 
MET C   O    doub N N 358 
MET C   OXT  sing N N 359 
MET CB  CG   sing N N 360 
MET CB  HB2  sing N N 361 
MET CB  HB3  sing N N 362 
MET CG  SD   sing N N 363 
MET CG  HG2  sing N N 364 
MET CG  HG3  sing N N 365 
MET SD  CE   sing N N 366 
MET CE  HE1  sing N N 367 
MET CE  HE2  sing N N 368 
MET CE  HE3  sing N N 369 
MET OXT HXT  sing N N 370 
PHE N   CA   sing N N 371 
PHE N   H    sing N N 372 
PHE N   H2   sing N N 373 
PHE CA  C    sing N N 374 
PHE CA  CB   sing N N 375 
PHE CA  HA   sing N N 376 
PHE C   O    doub N N 377 
PHE C   OXT  sing N N 378 
PHE CB  CG   sing N N 379 
PHE CB  HB2  sing N N 380 
PHE CB  HB3  sing N N 381 
PHE CG  CD1  doub Y N 382 
PHE CG  CD2  sing Y N 383 
PHE CD1 CE1  sing Y N 384 
PHE CD1 HD1  sing N N 385 
PHE CD2 CE2  doub Y N 386 
PHE CD2 HD2  sing N N 387 
PHE CE1 CZ   doub Y N 388 
PHE CE1 HE1  sing N N 389 
PHE CE2 CZ   sing Y N 390 
PHE CE2 HE2  sing N N 391 
PHE CZ  HZ   sing N N 392 
PHE OXT HXT  sing N N 393 
PRO N   CA   sing N N 394 
PRO N   CD   sing N N 395 
PRO N   H    sing N N 396 
PRO CA  C    sing N N 397 
PRO CA  CB   sing N N 398 
PRO CA  HA   sing N N 399 
PRO C   O    doub N N 400 
PRO C   OXT  sing N N 401 
PRO CB  CG   sing N N 402 
PRO CB  HB2  sing N N 403 
PRO CB  HB3  sing N N 404 
PRO CG  CD   sing N N 405 
PRO CG  HG2  sing N N 406 
PRO CG  HG3  sing N N 407 
PRO CD  HD2  sing N N 408 
PRO CD  HD3  sing N N 409 
PRO OXT HXT  sing N N 410 
SER N   CA   sing N N 411 
SER N   H    sing N N 412 
SER N   H2   sing N N 413 
SER CA  C    sing N N 414 
SER CA  CB   sing N N 415 
SER CA  HA   sing N N 416 
SER C   O    doub N N 417 
SER C   OXT  sing N N 418 
SER CB  OG   sing N N 419 
SER CB  HB2  sing N N 420 
SER CB  HB3  sing N N 421 
SER OG  HG   sing N N 422 
SER OXT HXT  sing N N 423 
THR N   CA   sing N N 424 
THR N   H    sing N N 425 
THR N   H2   sing N N 426 
THR CA  C    sing N N 427 
THR CA  CB   sing N N 428 
THR CA  HA   sing N N 429 
THR C   O    doub N N 430 
THR C   OXT  sing N N 431 
THR CB  OG1  sing N N 432 
THR CB  CG2  sing N N 433 
THR CB  HB   sing N N 434 
THR OG1 HG1  sing N N 435 
THR CG2 HG21 sing N N 436 
THR CG2 HG22 sing N N 437 
THR CG2 HG23 sing N N 438 
THR OXT HXT  sing N N 439 
TRP N   CA   sing N N 440 
TRP N   H    sing N N 441 
TRP N   H2   sing N N 442 
TRP CA  C    sing N N 443 
TRP CA  CB   sing N N 444 
TRP CA  HA   sing N N 445 
TRP C   O    doub N N 446 
TRP C   OXT  sing N N 447 
TRP CB  CG   sing N N 448 
TRP CB  HB2  sing N N 449 
TRP CB  HB3  sing N N 450 
TRP CG  CD1  doub Y N 451 
TRP CG  CD2  sing Y N 452 
TRP CD1 NE1  sing Y N 453 
TRP CD1 HD1  sing N N 454 
TRP CD2 CE2  doub Y N 455 
TRP CD2 CE3  sing Y N 456 
TRP NE1 CE2  sing Y N 457 
TRP NE1 HE1  sing N N 458 
TRP CE2 CZ2  sing Y N 459 
TRP CE3 CZ3  doub Y N 460 
TRP CE3 HE3  sing N N 461 
TRP CZ2 CH2  doub Y N 462 
TRP CZ2 HZ2  sing N N 463 
TRP CZ3 CH2  sing Y N 464 
TRP CZ3 HZ3  sing N N 465 
TRP CH2 HH2  sing N N 466 
TRP OXT HXT  sing N N 467 
TYR N   CA   sing N N 468 
TYR N   H    sing N N 469 
TYR N   H2   sing N N 470 
TYR CA  C    sing N N 471 
TYR CA  CB   sing N N 472 
TYR CA  HA   sing N N 473 
TYR C   O    doub N N 474 
TYR C   OXT  sing N N 475 
TYR CB  CG   sing N N 476 
TYR CB  HB2  sing N N 477 
TYR CB  HB3  sing N N 478 
TYR CG  CD1  doub Y N 479 
TYR CG  CD2  sing Y N 480 
TYR CD1 CE1  sing Y N 481 
TYR CD1 HD1  sing N N 482 
TYR CD2 CE2  doub Y N 483 
TYR CD2 HD2  sing N N 484 
TYR CE1 CZ   doub Y N 485 
TYR CE1 HE1  sing N N 486 
TYR CE2 CZ   sing Y N 487 
TYR CE2 HE2  sing N N 488 
TYR CZ  OH   sing N N 489 
TYR OH  HH   sing N N 490 
TYR OXT HXT  sing N N 491 
VAL N   CA   sing N N 492 
VAL N   H    sing N N 493 
VAL N   H2   sing N N 494 
VAL CA  C    sing N N 495 
VAL CA  CB   sing N N 496 
VAL CA  HA   sing N N 497 
VAL C   O    doub N N 498 
VAL C   OXT  sing N N 499 
VAL CB  CG1  sing N N 500 
VAL CB  CG2  sing N N 501 
VAL CB  HB   sing N N 502 
VAL CG1 HG11 sing N N 503 
VAL CG1 HG12 sing N N 504 
VAL CG1 HG13 sing N N 505 
VAL CG2 HG21 sing N N 506 
VAL CG2 HG22 sing N N 507 
VAL CG2 HG23 sing N N 508 
VAL OXT HXT  sing N N 509 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-01-26 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8Y2N 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'Cryo-EM structure of the apo Lac1-Lip1 complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          559292 
_em_entity_assembly_naturalsource.organism             'Saccharomyces cerevisiae (strain ATCC 204508 / S288c)' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8Y2N 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ILE A 1 71  ? 143.470 177.378 121.837 1.00 161.32 ? 71  ILE A N   1 
ATOM   2    C CA  . ILE A 1 71  ? 142.462 176.859 120.924 1.00 161.32 ? 71  ILE A CA  1 
ATOM   3    C C   . ILE A 1 71  ? 142.440 175.338 121.014 1.00 161.32 ? 71  ILE A C   1 
ATOM   4    O O   . ILE A 1 71  ? 143.458 174.685 120.815 1.00 161.32 ? 71  ILE A O   1 
ATOM   5    C CB  . ILE A 1 71  ? 142.712 177.323 119.485 1.00 161.32 ? 71  ILE A CB  1 
ATOM   6    C CG1 . ILE A 1 71  ? 142.637 178.849 119.395 1.00 161.32 ? 71  ILE A CG1 1 
ATOM   7    C CG2 . ILE A 1 71  ? 141.695 176.692 118.546 1.00 161.32 ? 71  ILE A CG2 1 
ATOM   8    C CD1 . ILE A 1 71  ? 143.977 179.546 119.543 1.00 161.32 ? 71  ILE A CD1 1 
ATOM   9    N N   . TRP A 1 72  ? 141.253 174.799 121.282 1.00 162.25 ? 72  TRP A N   1 
ATOM   10   C CA  . TRP A 1 72  ? 141.012 173.410 121.703 1.00 162.25 ? 72  TRP A CA  1 
ATOM   11   C C   . TRP A 1 72  ? 141.825 172.411 120.871 1.00 162.25 ? 72  TRP A C   1 
ATOM   12   O O   . TRP A 1 72  ? 142.789 171.827 121.389 1.00 162.25 ? 72  TRP A O   1 
ATOM   13   C CB  . TRP A 1 72  ? 139.495 173.247 121.681 1.00 162.25 ? 72  TRP A CB  1 
ATOM   14   C CG  . TRP A 1 72  ? 138.869 173.498 120.327 1.00 162.25 ? 72  TRP A CG  1 
ATOM   15   C CD1 . TRP A 1 72  ? 138.676 172.601 119.325 1.00 162.25 ? 72  TRP A CD1 1 
ATOM   16   C CD2 . TRP A 1 72  ? 138.378 174.752 119.835 1.00 162.25 ? 72  TRP A CD2 1 
ATOM   17   N NE1 . TRP A 1 72  ? 138.090 173.208 118.242 1.00 162.25 ? 72  TRP A NE1 1 
ATOM   18   C CE2 . TRP A 1 72  ? 137.895 174.532 118.532 1.00 162.25 ? 72  TRP A CE2 1 
ATOM   19   C CE3 . TRP A 1 72  ? 138.295 176.040 120.376 1.00 162.25 ? 72  TRP A CE3 1 
ATOM   20   C CZ2 . TRP A 1 72  ? 137.338 175.547 117.760 1.00 162.25 ? 72  TRP A CZ2 1 
ATOM   21   C CZ3 . TRP A 1 72  ? 137.742 177.046 119.608 1.00 162.25 ? 72  TRP A CZ3 1 
ATOM   22   C CH2 . TRP A 1 72  ? 137.270 176.794 118.314 1.00 162.25 ? 72  TRP A CH2 1 
ATOM   23   N N   . PHE A 1 73  ? 141.547 172.234 119.582 1.00 160.21 ? 73  PHE A N   1 
ATOM   24   C CA  . PHE A 1 73  ? 142.281 171.199 118.864 1.00 160.21 ? 73  PHE A CA  1 
ATOM   25   C C   . PHE A 1 73  ? 143.466 171.741 118.080 1.00 160.21 ? 73  PHE A C   1 
ATOM   26   O O   . PHE A 1 73  ? 144.367 170.964 117.744 1.00 160.21 ? 73  PHE A O   1 
ATOM   27   C CB  . PHE A 1 73  ? 141.348 170.396 117.952 1.00 160.21 ? 73  PHE A CB  1 
ATOM   28   C CG  . PHE A 1 73  ? 140.504 169.391 118.692 1.00 160.21 ? 73  PHE A CG  1 
ATOM   29   C CD1 . PHE A 1 73  ? 139.164 169.617 118.933 1.00 160.21 ? 73  PHE A CD1 1 
ATOM   30   C CD2 . PHE A 1 73  ? 141.071 168.224 119.170 1.00 160.21 ? 73  PHE A CD2 1 
ATOM   31   C CE1 . PHE A 1 73  ? 138.398 168.694 119.621 1.00 160.21 ? 73  PHE A CE1 1 
ATOM   32   C CE2 . PHE A 1 73  ? 140.313 167.296 119.858 1.00 160.21 ? 73  PHE A CE2 1 
ATOM   33   C CZ  . PHE A 1 73  ? 138.975 167.532 120.084 1.00 160.21 ? 73  PHE A CZ  1 
ATOM   34   N N   . SER A 1 74  ? 143.524 173.047 117.829 1.00 158.31 ? 74  SER A N   1 
ATOM   35   C CA  . SER A 1 74  ? 144.798 173.640 117.438 1.00 158.31 ? 74  SER A CA  1 
ATOM   36   C C   . SER A 1 74  ? 145.850 173.360 118.502 1.00 158.31 ? 74  SER A C   1 
ATOM   37   O O   . SER A 1 74  ? 146.992 172.997 118.193 1.00 158.31 ? 74  SER A O   1 
ATOM   38   C CB  . SER A 1 74  ? 144.636 175.143 117.217 1.00 158.31 ? 74  SER A CB  1 
ATOM   39   O OG  . SER A 1 74  ? 143.687 175.409 116.199 1.00 158.31 ? 74  SER A OG  1 
ATOM   40   N N   . PHE A 1 75  ? 145.469 173.485 119.774 1.00 156.46 ? 75  PHE A N   1 
ATOM   41   C CA  . PHE A 1 75  ? 146.418 173.170 120.830 1.00 156.46 ? 75  PHE A CA  1 
ATOM   42   C C   . PHE A 1 75  ? 146.535 171.672 121.060 1.00 156.46 ? 75  PHE A C   1 
ATOM   43   O O   . PHE A 1 75  ? 147.569 171.209 121.548 1.00 156.46 ? 75  PHE A O   1 
ATOM   44   C CB  . PHE A 1 75  ? 146.051 173.898 122.119 1.00 156.46 ? 75  PHE A CB  1 
ATOM   45   C CG  . PHE A 1 75  ? 146.682 175.251 122.231 1.00 156.46 ? 75  PHE A CG  1 
ATOM   46   C CD1 . PHE A 1 75  ? 146.428 176.222 121.279 1.00 156.46 ? 75  PHE A CD1 1 
ATOM   47   C CD2 . PHE A 1 75  ? 147.552 175.545 123.264 1.00 156.46 ? 75  PHE A CD2 1 
ATOM   48   C CE1 . PHE A 1 75  ? 147.010 177.466 121.367 1.00 156.46 ? 75  PHE A CE1 1 
ATOM   49   C CE2 . PHE A 1 75  ? 148.140 176.788 123.356 1.00 156.46 ? 75  PHE A CE2 1 
ATOM   50   C CZ  . PHE A 1 75  ? 147.869 177.749 122.406 1.00 156.46 ? 75  PHE A CZ  1 
ATOM   51   N N   . ARG A 1 76  ? 145.528 170.879 120.684 1.00 155.93 ? 76  ARG A N   1 
ATOM   52   C CA  . ARG A 1 76  ? 145.785 169.442 120.682 1.00 155.93 ? 76  ARG A CA  1 
ATOM   53   C C   . ARG A 1 76  ? 146.889 169.099 119.690 1.00 155.93 ? 76  ARG A C   1 
ATOM   54   O O   . ARG A 1 76  ? 147.788 168.306 119.992 1.00 155.93 ? 76  ARG A O   1 
ATOM   55   C CB  . ARG A 1 76  ? 144.530 168.633 120.362 1.00 155.93 ? 76  ARG A CB  1 
ATOM   56   C CG  . ARG A 1 76  ? 144.773 167.157 120.662 1.00 155.93 ? 76  ARG A CG  1 
ATOM   57   C CD  . ARG A 1 76  ? 143.641 166.227 120.282 1.00 155.93 ? 76  ARG A CD  1 
ATOM   58   N NE  . ARG A 1 76  ? 143.517 166.078 118.836 1.00 155.93 ? 76  ARG A NE  1 
ATOM   59   C CZ  . ARG A 1 76  ? 142.649 165.266 118.244 1.00 155.93 ? 76  ARG A CZ  1 
ATOM   60   N NH1 . ARG A 1 76  ? 142.603 165.192 116.921 1.00 155.93 ? 76  ARG A NH1 1 
ATOM   61   N NH2 . ARG A 1 76  ? 141.836 164.516 118.975 1.00 155.93 ? 76  ARG A NH2 1 
ATOM   62   N N   . GLU A 1 77  ? 146.858 169.776 118.546 1.00 153.56 ? 77  GLU A N   1 
ATOM   63   C CA  . GLU A 1 77  ? 147.868 169.598 117.517 1.00 153.56 ? 77  GLU A CA  1 
ATOM   64   C C   . GLU A 1 77  ? 149.224 170.045 118.058 1.00 153.56 ? 77  GLU A C   1 
ATOM   65   O O   . GLU A 1 77  ? 150.219 169.335 117.905 1.00 153.56 ? 77  GLU A O   1 
ATOM   66   C CB  . GLU A 1 77  ? 147.508 170.400 116.265 1.00 153.56 ? 77  GLU A CB  1 
ATOM   67   C CG  . GLU A 1 77  ? 148.692 171.092 115.610 1.00 153.56 ? 77  GLU A CG  1 
ATOM   68   C CD  . GLU A 1 77  ? 149.175 170.371 114.367 1.00 153.56 ? 77  GLU A CD  1 
ATOM   69   O OE1 . GLU A 1 77  ? 149.182 169.122 114.368 1.00 153.56 ? 77  GLU A OE1 1 
ATOM   70   O OE2 . GLU A 1 77  ? 149.548 171.052 113.389 1.00 153.56 ? 77  GLU A OE2 1 
ATOM   71   N N   . ILE A 1 78  ? 149.269 171.217 118.692 1.00 148.64 ? 78  ILE A N   1 
ATOM   72   C CA  . ILE A 1 78  ? 150.526 171.700 119.252 1.00 148.64 ? 78  ILE A CA  1 
ATOM   73   C C   . ILE A 1 78  ? 151.036 170.742 120.319 1.00 148.64 ? 78  ILE A C   1 
ATOM   74   O O   . ILE A 1 78  ? 152.252 170.650 120.526 1.00 148.64 ? 78  ILE A O   1 
ATOM   75   C CB  . ILE A 1 78  ? 150.398 173.123 119.825 1.00 148.64 ? 78  ILE A CB  1 
ATOM   76   C CG1 . ILE A 1 78  ? 151.758 173.809 119.828 1.00 148.64 ? 78  ILE A CG1 1 
ATOM   77   C CG2 . ILE A 1 78  ? 149.934 173.103 121.258 1.00 148.64 ? 78  ILE A CG2 1 
ATOM   78   C CD1 . ILE A 1 78  ? 152.267 174.108 118.447 1.00 148.64 ? 78  ILE A CD1 1 
ATOM   79   N N   . SER A 1 79  ? 150.138 170.015 120.992 1.00 145.51 ? 79  SER A N   1 
ATOM   80   C CA  . SER A 1 79  ? 150.563 168.952 121.895 1.00 145.51 ? 79  SER A CA  1 
ATOM   81   C C   . SER A 1 79  ? 151.161 167.790 121.115 1.00 145.51 ? 79  SER A C   1 
ATOM   82   O O   . SER A 1 79  ? 152.110 167.147 121.571 1.00 145.51 ? 79  SER A O   1 
ATOM   83   C CB  . SER A 1 79  ? 149.390 168.472 122.746 1.00 145.51 ? 79  SER A CB  1 
ATOM   84   O OG  . SER A 1 79  ? 148.542 167.621 121.999 1.00 145.51 ? 79  SER A OG  1 
ATOM   85   N N   . TYR A 1 80  ? 150.661 167.577 119.904 1.00 149.87 ? 80  TYR A N   1 
ATOM   86   C CA  . TYR A 1 80  ? 151.201 166.536 119.043 1.00 149.87 ? 80  TYR A CA  1 
ATOM   87   C C   . TYR A 1 80  ? 152.617 166.957 118.654 1.00 149.87 ? 80  TYR A C   1 
ATOM   88   O O   . TYR A 1 80  ? 153.471 166.118 118.362 1.00 149.87 ? 80  TYR A O   1 
ATOM   89   C CB  . TYR A 1 80  ? 150.337 166.362 117.796 1.00 149.87 ? 80  TYR A CB  1 
ATOM   90   C CG  . TYR A 1 80  ? 151.092 165.831 116.598 1.00 149.87 ? 80  TYR A CG  1 
ATOM   91   C CD1 . TYR A 1 80  ? 151.824 166.683 115.781 1.00 149.87 ? 80  TYR A CD1 1 
ATOM   92   C CD2 . TYR A 1 80  ? 151.074 164.479 116.285 1.00 149.87 ? 80  TYR A CD2 1 
ATOM   93   C CE1 . TYR A 1 80  ? 152.517 166.202 114.686 1.00 149.87 ? 80  TYR A CE1 1 
ATOM   94   C CE2 . TYR A 1 80  ? 151.763 163.989 115.192 1.00 149.87 ? 80  TYR A CE2 1 
ATOM   95   C CZ  . TYR A 1 80  ? 152.483 164.855 114.397 1.00 149.87 ? 80  TYR A CZ  1 
ATOM   96   O OH  . TYR A 1 80  ? 153.171 164.372 113.307 1.00 149.87 ? 80  TYR A OH  1 
ATOM   97   N N   . ARG A 1 81  ? 152.853 168.268 118.657 1.00 143.82 ? 81  ARG A N   1 
ATOM   98   C CA  . ARG A 1 81  ? 154.154 168.833 118.330 1.00 143.82 ? 81  ARG A CA  1 
ATOM   99   C C   . ARG A 1 81  ? 155.050 168.864 119.570 1.00 143.82 ? 81  ARG A C   1 
ATOM   100  O O   . ARG A 1 81  ? 156.275 168.909 119.458 1.00 143.82 ? 81  ARG A O   1 
ATOM   101  C CB  . ARG A 1 81  ? 153.999 170.243 117.757 1.00 143.82 ? 81  ARG A CB  1 
ATOM   102  C CG  . ARG A 1 81  ? 154.415 170.369 116.301 1.00 143.82 ? 81  ARG A CG  1 
ATOM   103  C CD  . ARG A 1 81  ? 155.714 169.627 116.032 1.00 143.82 ? 81  ARG A CD  1 
ATOM   104  N NE  . ARG A 1 81  ? 155.574 168.651 114.956 1.00 143.82 ? 81  ARG A NE  1 
ATOM   105  C CZ  . ARG A 1 81  ? 156.430 168.523 113.947 1.00 143.82 ? 81  ARG A CZ  1 
ATOM   106  N NH1 . ARG A 1 81  ? 157.492 169.313 113.873 1.00 143.82 ? 81  ARG A NH1 1 
ATOM   107  N NH2 . ARG A 1 81  ? 156.223 167.607 113.011 1.00 143.82 ? 81  ARG A NH2 1 
ATOM   108  N N   . HIS A 1 82  ? 154.433 168.838 120.750 1.00 132.44 ? 82  HIS A N   1 
ATOM   109  C CA  . HIS A 1 82  ? 155.179 168.858 122.013 1.00 132.44 ? 82  HIS A CA  1 
ATOM   110  C C   . HIS A 1 82  ? 154.402 167.985 123.002 1.00 132.44 ? 82  HIS A C   1 
ATOM   111  O O   . HIS A 1 82  ? 153.492 168.438 123.695 1.00 132.44 ? 82  HIS A O   1 
ATOM   112  C CB  . HIS A 1 82  ? 155.375 170.274 122.552 1.00 132.44 ? 82  HIS A CB  1 
ATOM   113  C CG  . HIS A 1 82  ? 156.377 171.078 121.786 1.00 132.44 ? 82  HIS A CG  1 
ATOM   114  N ND1 . HIS A 1 82  ? 157.316 170.503 120.958 1.00 132.44 ? 82  HIS A ND1 1 
ATOM   115  C CD2 . HIS A 1 82  ? 156.593 172.413 121.729 1.00 132.44 ? 82  HIS A CD2 1 
ATOM   116  C CE1 . HIS A 1 82  ? 158.063 171.450 120.419 1.00 132.44 ? 82  HIS A CE1 1 
ATOM   117  N NE2 . HIS A 1 82  ? 157.646 172.618 120.871 1.00 132.44 ? 82  HIS A NE2 1 
ATOM   118  N N   . ALA A 1 83  ? 154.782 166.711 123.067 1.00 121.58 ? 83  ALA A N   1 
ATOM   119  C CA  . ALA A 1 83  ? 154.016 165.707 123.798 1.00 121.58 ? 83  ALA A CA  1 
ATOM   120  C C   . ALA A 1 83  ? 153.930 165.995 125.291 1.00 121.58 ? 83  ALA A C   1 
ATOM   121  O O   . ALA A 1 83  ? 152.899 165.740 125.920 1.00 121.58 ? 83  ALA A O   1 
ATOM   122  C CB  . ALA A 1 83  ? 154.620 164.321 123.575 1.00 121.58 ? 83  ALA A CB  1 
ATOM   123  N N   . TRP A 1 84  ? 155.005 166.524 125.864 1.00 112.57 ? 84  TRP A N   1 
ATOM   124  C CA  . TRP A 1 84  ? 155.124 166.703 127.306 1.00 112.57 ? 84  TRP A CA  1 
ATOM   125  C C   . TRP A 1 84  ? 154.211 167.786 127.865 1.00 112.57 ? 84  TRP A C   1 
ATOM   126  O O   . TRP A 1 84  ? 154.088 167.922 129.089 1.00 112.57 ? 84  TRP A O   1 
ATOM   127  C CB  . TRP A 1 84  ? 156.569 167.043 127.652 1.00 112.57 ? 84  TRP A CB  1 
ATOM   128  C CG  . TRP A 1 84  ? 157.119 168.114 126.785 1.00 112.57 ? 84  TRP A CG  1 
ATOM   129  C CD1 . TRP A 1 84  ? 157.794 167.951 125.618 1.00 112.57 ? 84  TRP A CD1 1 
ATOM   130  C CD2 . TRP A 1 84  ? 157.036 169.522 127.009 1.00 112.57 ? 84  TRP A CD2 1 
ATOM   131  N NE1 . TRP A 1 84  ? 158.142 169.171 125.098 1.00 112.57 ? 84  TRP A NE1 1 
ATOM   132  C CE2 . TRP A 1 84  ? 157.687 170.154 125.935 1.00 112.57 ? 84  TRP A CE2 1 
ATOM   133  C CE3 . TRP A 1 84  ? 156.476 170.312 128.015 1.00 112.57 ? 84  TRP A CE3 1 
ATOM   134  C CZ2 . TRP A 1 84  ? 157.798 171.536 125.840 1.00 112.57 ? 84  TRP A CZ2 1 
ATOM   135  C CZ3 . TRP A 1 84  ? 156.586 171.682 127.917 1.00 112.57 ? 84  TRP A CZ3 1 
ATOM   136  C CH2 . TRP A 1 84  ? 157.241 172.281 126.839 1.00 112.57 ? 84  TRP A CH2 1 
ATOM   137  N N   . ILE A 1 85  ? 153.580 168.568 126.989 1.00 111.40 ? 85  ILE A N   1 
ATOM   138  C CA  . ILE A 1 85  ? 152.940 169.799 127.436 1.00 111.40 ? 85  ILE A CA  1 
ATOM   139  C C   . ILE A 1 85  ? 151.763 169.538 128.377 1.00 111.40 ? 85  ILE A C   1 
ATOM   140  O O   . ILE A 1 85  ? 151.598 170.255 129.367 1.00 111.40 ? 85  ILE A O   1 
ATOM   141  C CB  . ILE A 1 85  ? 152.533 170.658 126.227 1.00 111.40 ? 85  ILE A CB  1 
ATOM   142  C CG1 . ILE A 1 85  ? 152.153 172.064 126.686 1.00 111.40 ? 85  ILE A CG1 1 
ATOM   143  C CG2 . ILE A 1 85  ? 151.404 170.021 125.442 1.00 111.40 ? 85  ILE A CG2 1 
ATOM   144  C CD1 . ILE A 1 85  ? 153.309 172.839 127.260 1.00 111.40 ? 85  ILE A CD1 1 
ATOM   145  N N   . ALA A 1 86  ? 150.924 168.539 128.101 1.00 107.09 ? 86  ALA A N   1 
ATOM   146  C CA  . ALA A 1 86  ? 149.806 168.263 129.003 1.00 107.09 ? 86  ALA A CA  1 
ATOM   147  C C   . ALA A 1 86  ? 150.261 167.790 130.380 1.00 107.09 ? 86  ALA A C   1 
ATOM   148  O O   . ALA A 1 86  ? 149.728 168.291 131.389 1.00 107.09 ? 86  ALA A O   1 
ATOM   149  C CB  . ALA A 1 86  ? 148.847 167.265 128.348 1.00 107.09 ? 86  ALA A CB  1 
ATOM   150  N N   . PRO A 1 87  ? 151.191 166.835 130.509 1.00 103.95 ? 87  PRO A N   1 
ATOM   151  C CA  . PRO A 1 87  ? 151.721 166.537 131.846 1.00 103.95 ? 87  PRO A CA  1 
ATOM   152  C C   . PRO A 1 87  ? 152.339 167.744 132.520 1.00 103.95 ? 87  PRO A C   1 
ATOM   153  O O   . PRO A 1 87  ? 152.183 167.913 133.734 1.00 103.95 ? 87  PRO A O   1 
ATOM   154  C CB  . PRO A 1 87  ? 152.749 165.438 131.567 1.00 103.95 ? 87  PRO A CB  1 
ATOM   155  C CG  . PRO A 1 87  ? 152.245 164.774 130.360 1.00 103.95 ? 87  PRO A CG  1 
ATOM   156  C CD  . PRO A 1 87  ? 151.709 165.880 129.513 1.00 103.95 ? 87  PRO A CD  1 
ATOM   157  N N   . LEU A 1 88  ? 153.033 168.605 131.772 1.00 103.49 ? 88  LEU A N   1 
ATOM   158  C CA  . LEU A 1 88  ? 153.583 169.794 132.411 1.00 103.49 ? 88  LEU A CA  1 
ATOM   159  C C   . LEU A 1 88  ? 152.473 170.688 132.940 1.00 103.49 ? 88  LEU A C   1 
ATOM   160  O O   . LEU A 1 88  ? 152.600 171.266 134.022 1.00 103.49 ? 88  LEU A O   1 
ATOM   161  C CB  . LEU A 1 88  ? 154.479 170.574 131.455 1.00 103.49 ? 88  LEU A CB  1 
ATOM   162  C CG  . LEU A 1 88  ? 155.074 171.806 132.139 1.00 103.49 ? 88  LEU A CG  1 
ATOM   163  C CD1 . LEU A 1 88  ? 155.813 171.392 133.388 1.00 103.49 ? 88  LEU A CD1 1 
ATOM   164  C CD2 . LEU A 1 88  ? 155.992 172.580 131.221 1.00 103.49 ? 88  LEU A CD2 1 
ATOM   165  N N   . MET A 1 89  ? 151.374 170.762 132.197 1.00 105.51 ? 89  MET A N   1 
ATOM   166  C CA  . MET A 1 89  ? 150.228 171.567 132.599 1.00 105.51 ? 89  MET A CA  1 
ATOM   167  C C   . MET A 1 89  ? 149.629 171.038 133.899 1.00 105.51 ? 89  MET A C   1 
ATOM   168  O O   . MET A 1 89  ? 149.299 171.812 134.798 1.00 105.51 ? 89  MET A O   1 
ATOM   169  C CB  . MET A 1 89  ? 149.168 171.581 131.497 1.00 105.51 ? 89  MET A CB  1 
ATOM   170  C CG  . MET A 1 89  ? 149.536 172.430 130.291 1.00 105.51 ? 89  MET A CG  1 
ATOM   171  S SD  . MET A 1 89  ? 149.428 174.199 130.626 1.00 105.51 ? 89  MET A SD  1 
ATOM   172  C CE  . MET A 1 89  ? 150.062 174.872 129.092 1.00 105.51 ? 89  MET A CE  1 
ATOM   173  N N   . ILE A 1 90  ? 149.489 169.718 133.996 1.00 100.15 ? 90  ILE A N   1 
ATOM   174  C CA  . ILE A 1 90  ? 148.930 169.101 135.199 1.00 100.15 ? 90  ILE A CA  1 
ATOM   175  C C   . ILE A 1 90  ? 149.851 169.327 136.392 1.00 100.15 ? 90  ILE A C   1 
ATOM   176  O O   . ILE A 1 90  ? 149.407 169.713 137.483 1.00 100.15 ? 90  ILE A O   1 
ATOM   177  C CB  . ILE A 1 90  ? 148.668 167.605 134.966 1.00 100.15 ? 90  ILE A CB  1 
ATOM   178  C CG1 . ILE A 1 90  ? 147.597 167.410 133.894 1.00 100.15 ? 90  ILE A CG1 1 
ATOM   179  C CG2 . ILE A 1 90  ? 148.260 166.937 136.260 1.00 100.15 ? 90  ILE A CG2 1 
ATOM   180  C CD1 . ILE A 1 90  ? 147.088 165.989 133.791 1.00 100.15 ? 90  ILE A CD1 1 
ATOM   181  N N   . LEU A 1 91  ? 151.151 169.099 136.201 1.00 95.53  ? 91  LEU A N   1 
ATOM   182  C CA  . LEU A 1 91  ? 152.110 169.309 137.277 1.00 95.53  ? 91  LEU A CA  1 
ATOM   183  C C   . LEU A 1 91  ? 152.121 170.756 137.745 1.00 95.53  ? 91  LEU A C   1 
ATOM   184  O O   . LEU A 1 91  ? 152.138 171.029 138.949 1.00 95.53  ? 91  LEU A O   1 
ATOM   185  C CB  . LEU A 1 91  ? 153.505 168.889 136.830 1.00 95.53  ? 91  LEU A CB  1 
ATOM   186  C CG  . LEU A 1 91  ? 153.938 167.451 137.064 1.00 95.53  ? 91  LEU A CG  1 
ATOM   187  C CD1 . LEU A 1 91  ? 153.176 166.474 136.220 1.00 95.53  ? 91  LEU A CD1 1 
ATOM   188  C CD2 . LEU A 1 91  ? 155.399 167.392 136.737 1.00 95.53  ? 91  LEU A CD2 1 
ATOM   189  N N   . ILE A 1 92  ? 152.144 171.703 136.808 1.00 101.51 ? 92  ILE A N   1 
ATOM   190  C CA  . ILE A 1 92  ? 152.245 173.099 137.208 1.00 101.51 ? 92  ILE A CA  1 
ATOM   191  C C   . ILE A 1 92  ? 150.976 173.534 137.920 1.00 101.51 ? 92  ILE A C   1 
ATOM   192  O O   . ILE A 1 92  ? 151.035 174.296 138.890 1.00 101.51 ? 92  ILE A O   1 
ATOM   193  C CB  . ILE A 1 92  ? 152.584 173.997 136.000 1.00 101.51 ? 92  ILE A CB  1 
ATOM   194  C CG1 . ILE A 1 92  ? 153.063 175.364 136.481 1.00 101.51 ? 92  ILE A CG1 1 
ATOM   195  C CG2 . ILE A 1 92  ? 151.404 174.147 135.059 1.00 101.51 ? 92  ILE A CG2 1 
ATOM   196  C CD1 . ILE A 1 92  ? 154.365 175.310 137.240 1.00 101.51 ? 92  ILE A CD1 1 
ATOM   197  N N   . ALA A 1 93  ? 149.818 173.022 137.496 1.00 101.60 ? 93  ALA A N   1 
ATOM   198  C CA  . ALA A 1 93  ? 148.577 173.347 138.188 1.00 101.60 ? 93  ALA A CA  1 
ATOM   199  C C   . ALA A 1 93  ? 148.591 172.818 139.616 1.00 101.60 ? 93  ALA A C   1 
ATOM   200  O O   . ALA A 1 93  ? 148.265 173.546 140.561 1.00 101.60 ? 93  ALA A O   1 
ATOM   201  C CB  . ALA A 1 93  ? 147.383 172.788 137.417 1.00 101.60 ? 93  ALA A CB  1 
ATOM   202  N N   . VAL A 1 94  ? 148.977 171.550 139.798 1.00 97.01  ? 94  VAL A N   1 
ATOM   203  C CA  . VAL A 1 94  ? 148.959 170.975 141.143 1.00 97.01  ? 94  VAL A CA  1 
ATOM   204  C C   . VAL A 1 94  ? 149.981 171.662 142.041 1.00 97.01  ? 94  VAL A C   1 
ATOM   205  O O   . VAL A 1 94  ? 149.687 172.003 143.192 1.00 97.01  ? 94  VAL A O   1 
ATOM   206  C CB  . VAL A 1 94  ? 149.184 169.456 141.087 1.00 97.01  ? 94  VAL A CB  1 
ATOM   207  C CG1 . VAL A 1 94  ? 149.450 168.923 142.473 1.00 97.01  ? 94  VAL A CG1 1 
ATOM   208  C CG2 . VAL A 1 94  ? 147.972 168.775 140.499 1.00 97.01  ? 94  VAL A CG2 1 
ATOM   209  N N   . TYR A 1 95  ? 151.194 171.880 141.534 1.00 96.49  ? 95  TYR A N   1 
ATOM   210  C CA  . TYR A 1 95  ? 152.209 172.556 142.330 1.00 96.49  ? 95  TYR A CA  1 
ATOM   211  C C   . TYR A 1 95  ? 151.781 173.972 142.678 1.00 96.49  ? 95  TYR A C   1 
ATOM   212  O O   . TYR A 1 95  ? 152.018 174.440 143.797 1.00 96.49  ? 95  TYR A O   1 
ATOM   213  C CB  . TYR A 1 95  ? 153.542 172.575 141.588 1.00 96.49  ? 95  TYR A CB  1 
ATOM   214  C CG  . TYR A 1 95  ? 154.391 171.350 141.802 1.00 96.49  ? 95  TYR A CG  1 
ATOM   215  C CD1 . TYR A 1 95  ? 153.937 170.096 141.445 1.00 96.49  ? 95  TYR A CD1 1 
ATOM   216  C CD2 . TYR A 1 95  ? 155.653 171.450 142.360 1.00 96.49  ? 95  TYR A CD2 1 
ATOM   217  C CE1 . TYR A 1 95  ? 154.713 168.978 141.638 1.00 96.49  ? 95  TYR A CE1 1 
ATOM   218  C CE2 . TYR A 1 95  ? 156.436 170.335 142.557 1.00 96.49  ? 95  TYR A CE2 1 
ATOM   219  C CZ  . TYR A 1 95  ? 155.958 169.103 142.193 1.00 96.49  ? 95  TYR A CZ  1 
ATOM   220  O OH  . TYR A 1 95  ? 156.732 167.987 142.387 1.00 96.49  ? 95  TYR A OH  1 
ATOM   221  N N   . SER A 1 96  ? 151.159 174.673 141.730 1.00 103.00 ? 96  SER A N   1 
ATOM   222  C CA  . SER A 1 96  ? 150.708 176.031 141.986 1.00 103.00 ? 96  SER A CA  1 
ATOM   223  C C   . SER A 1 96  ? 149.637 176.050 143.063 1.00 103.00 ? 96  SER A C   1 
ATOM   224  O O   . SER A 1 96  ? 149.665 176.888 143.971 1.00 103.00 ? 96  SER A O   1 
ATOM   225  C CB  . SER A 1 96  ? 150.187 176.638 140.689 1.00 103.00 ? 96  SER A CB  1 
ATOM   226  O OG  . SER A 1 96  ? 151.125 176.446 139.646 1.00 103.00 ? 96  SER A OG  1 
ATOM   227  N N   . ALA A 1 97  ? 148.691 175.115 142.990 1.00 103.88 ? 97  ALA A N   1 
ATOM   228  C CA  . ALA A 1 97  ? 147.652 175.044 144.007 1.00 103.88 ? 97  ALA A CA  1 
ATOM   229  C C   . ALA A 1 97  ? 148.250 174.745 145.377 1.00 103.88 ? 97  ALA A C   1 
ATOM   230  O O   . ALA A 1 97  ? 147.839 175.327 146.387 1.00 103.88 ? 97  ALA A O   1 
ATOM   231  C CB  . ALA A 1 97  ? 146.615 173.991 143.620 1.00 103.88 ? 97  ALA A CB  1 
ATOM   232  N N   . TYR A 1 98  ? 149.233 173.846 145.431 1.00 102.99 ? 98  TYR A N   1 
ATOM   233  C CA  . TYR A 1 98  ? 149.813 173.487 146.722 1.00 102.99 ? 98  TYR A CA  1 
ATOM   234  C C   . TYR A 1 98  ? 150.650 174.615 147.302 1.00 102.99 ? 98  TYR A C   1 
ATOM   235  O O   . TYR A 1 98  ? 150.661 174.809 148.521 1.00 102.99 ? 98  TYR A O   1 
ATOM   236  C CB  . TYR A 1 98  ? 150.653 172.217 146.592 1.00 102.99 ? 98  TYR A CB  1 
ATOM   237  C CG  . TYR A 1 98  ? 151.433 171.855 147.837 1.00 102.99 ? 98  TYR A CG  1 
ATOM   238  C CD1 . TYR A 1 98  ? 150.855 171.098 148.840 1.00 102.99 ? 98  TYR A CD1 1 
ATOM   239  C CD2 . TYR A 1 98  ? 152.755 172.238 147.991 1.00 102.99 ? 98  TYR A CD2 1 
ATOM   240  C CE1 . TYR A 1 98  ? 151.558 170.758 149.970 1.00 102.99 ? 98  TYR A CE1 1 
ATOM   241  C CE2 . TYR A 1 98  ? 153.466 171.899 149.120 1.00 102.99 ? 98  TYR A CE2 1 
ATOM   242  C CZ  . TYR A 1 98  ? 152.862 171.159 150.104 1.00 102.99 ? 98  TYR A CZ  1 
ATOM   243  O OH  . TYR A 1 98  ? 153.564 170.816 151.234 1.00 102.99 ? 98  TYR A OH  1 
ATOM   244  N N   . PHE A 1 99  ? 151.357 175.365 146.463 1.00 106.72 ? 99  PHE A N   1 
ATOM   245  C CA  . PHE A 1 99  ? 152.284 176.363 146.974 1.00 106.72 ? 99  PHE A CA  1 
ATOM   246  C C   . PHE A 1 99  ? 151.643 177.721 147.212 1.00 106.72 ? 99  PHE A C   1 
ATOM   247  O O   . PHE A 1 99  ? 152.089 178.455 148.101 1.00 106.72 ? 99  PHE A O   1 
ATOM   248  C CB  . PHE A 1 99  ? 153.468 176.513 146.020 1.00 106.72 ? 99  PHE A CB  1 
ATOM   249  C CG  . PHE A 1 99  ? 154.498 175.438 146.176 1.00 106.72 ? 99  PHE A CG  1 
ATOM   250  C CD1 . PHE A 1 99  ? 154.977 175.103 147.431 1.00 106.72 ? 99  PHE A CD1 1 
ATOM   251  C CD2 . PHE A 1 99  ? 154.976 174.753 145.078 1.00 106.72 ? 99  PHE A CD2 1 
ATOM   252  C CE1 . PHE A 1 99  ? 155.918 174.112 147.587 1.00 106.72 ? 99  PHE A CE1 1 
ATOM   253  C CE2 . PHE A 1 99  ? 155.918 173.762 145.227 1.00 106.72 ? 99  PHE A CE2 1 
ATOM   254  C CZ  . PHE A 1 99  ? 156.389 173.441 146.485 1.00 106.72 ? 99  PHE A CZ  1 
ATOM   255  N N   . THR A 1 100 ? 150.614 178.084 146.444 1.00 110.21 ? 100 THR A N   1 
ATOM   256  C CA  . THR A 1 100 ? 149.940 179.353 146.691 1.00 110.21 ? 100 THR A CA  1 
ATOM   257  C C   . THR A 1 100 ? 149.003 179.263 147.885 1.00 110.21 ? 100 THR A C   1 
ATOM   258  O O   . THR A 1 100 ? 148.599 180.291 148.438 1.00 110.21 ? 100 THR A O   1 
ATOM   259  C CB  . THR A 1 100 ? 149.163 179.796 145.455 1.00 110.21 ? 100 THR A CB  1 
ATOM   260  O OG1 . THR A 1 100 ? 148.162 178.819 145.147 1.00 110.21 ? 100 THR A OG1 1 
ATOM   261  C CG2 . THR A 1 100 ? 150.098 179.969 144.269 1.00 110.21 ? 100 THR A CG2 1 
ATOM   262  N N   . SER A 1 101 ? 148.647 178.047 148.296 1.00 112.44 ? 101 SER A N   1 
ATOM   263  C CA  . SER A 1 101 ? 147.721 177.858 149.403 1.00 112.44 ? 101 SER A CA  1 
ATOM   264  C C   . SER A 1 101 ? 148.314 178.361 150.712 1.00 112.44 ? 101 SER A C   1 
ATOM   265  O O   . SER A 1 101 ? 147.582 178.608 151.676 1.00 112.44 ? 101 SER A O   1 
ATOM   266  C CB  . SER A 1 101 ? 147.335 176.386 149.527 1.00 112.44 ? 101 SER A CB  1 
ATOM   267  O OG  . SER A 1 101 ? 146.904 175.870 148.281 1.00 112.44 ? 101 SER A OG  1 
ATOM   268  N N   . GLY A 1 102 ? 149.632 178.508 150.762 1.00 115.95 ? 102 GLY A N   1 
ATOM   269  C CA  . GLY A 1 102 ? 150.273 178.995 151.964 1.00 115.95 ? 102 GLY A CA  1 
ATOM   270  C C   . GLY A 1 102 ? 150.499 177.914 152.999 1.00 115.95 ? 102 GLY A C   1 
ATOM   271  O O   . GLY A 1 102 ? 151.627 177.713 153.457 1.00 115.95 ? 102 GLY A O   1 
ATOM   272  N N   . ASN A 1 103 ? 149.436 177.203 153.375 1.00 118.73 ? 103 ASN A N   1 
ATOM   273  C CA  . ASN A 1 103 ? 149.521 176.164 154.402 1.00 118.73 ? 103 ASN A CA  1 
ATOM   274  C C   . ASN A 1 103 ? 150.180 174.912 153.834 1.00 118.73 ? 103 ASN A C   1 
ATOM   275  O O   . ASN A 1 103 ? 149.606 173.822 153.817 1.00 118.73 ? 103 ASN A O   1 
ATOM   276  C CB  . ASN A 1 103 ? 148.141 175.878 154.986 1.00 118.73 ? 103 ASN A CB  1 
ATOM   277  C CG  . ASN A 1 103 ? 147.159 175.325 153.965 1.00 118.73 ? 103 ASN A CG  1 
ATOM   278  O OD1 . ASN A 1 103 ? 147.510 175.032 152.824 1.00 118.73 ? 103 ASN A OD1 1 
ATOM   279  N ND2 . ASN A 1 103 ? 145.911 175.166 154.387 1.00 118.73 ? 103 ASN A ND2 1 
ATOM   280  N N   . THR A 1 104 ? 151.429 175.056 153.412 1.00 114.81 ? 104 THR A N   1 
ATOM   281  C CA  . THR A 1 104 ? 152.231 173.936 152.933 1.00 114.81 ? 104 THR A CA  1 
ATOM   282  C C   . THR A 1 104 ? 152.559 173.097 154.163 1.00 114.81 ? 104 THR A C   1 
ATOM   283  O O   . THR A 1 104 ? 153.680 173.121 154.673 1.00 114.81 ? 104 THR A O   1 
ATOM   284  C CB  . THR A 1 104 ? 153.486 174.416 152.229 1.00 114.81 ? 104 THR A CB  1 
ATOM   285  O OG1 . THR A 1 104 ? 154.389 174.968 153.193 1.00 114.81 ? 104 THR A OG1 1 
ATOM   286  C CG2 . THR A 1 104 ? 153.131 175.488 151.213 1.00 114.81 ? 104 THR A CG2 1 
ATOM   287  N N   . THR A 1 105 ? 151.562 172.360 154.644 1.00 112.08 ? 105 THR A N   1 
ATOM   288  C CA  . THR A 1 105 ? 151.676 171.619 155.888 1.00 112.08 ? 105 THR A CA  1 
ATOM   289  C C   . THR A 1 105 ? 151.556 170.137 155.577 1.00 112.08 ? 105 THR A C   1 
ATOM   290  O O   . THR A 1 105 ? 151.449 169.731 154.420 1.00 112.08 ? 105 THR A O   1 
ATOM   291  C CB  . THR A 1 105 ? 150.606 172.052 156.891 1.00 112.08 ? 105 THR A CB  1 
ATOM   292  O OG1 . THR A 1 105 ? 149.308 171.771 156.352 1.00 112.08 ? 105 THR A OG1 1 
ATOM   293  C CG2 . THR A 1 105 ? 150.714 173.540 157.160 1.00 112.08 ? 105 THR A CG2 1 
ATOM   294  N N   . LYS A 1 106 ? 151.566 169.324 156.633 1.00 108.41 ? 106 LYS A N   1 
ATOM   295  C CA  . LYS A 1 106 ? 151.421 167.890 156.437 1.00 108.41 ? 106 LYS A CA  1 
ATOM   296  C C   . LYS A 1 106 ? 149.996 167.506 156.094 1.00 108.41 ? 106 LYS A C   1 
ATOM   297  O O   . LYS A 1 106 ? 149.707 166.318 155.925 1.00 108.41 ? 106 LYS A O   1 
ATOM   298  C CB  . LYS A 1 106 ? 151.864 167.120 157.680 1.00 108.41 ? 106 LYS A CB  1 
ATOM   299  C CG  . LYS A 1 106 ? 150.987 167.324 158.895 1.00 108.41 ? 106 LYS A CG  1 
ATOM   300  C CD  . LYS A 1 106 ? 151.540 166.562 160.085 1.00 108.41 ? 106 LYS A CD  1 
ATOM   301  C CE  . LYS A 1 106 ? 151.393 165.067 159.895 1.00 108.41 ? 106 LYS A CE  1 
ATOM   302  N NZ  . LYS A 1 106 ? 149.965 164.657 159.883 1.00 108.41 ? 106 LYS A NZ  1 
ATOM   303  N N   . THR A 1 107 ? 149.060 168.458 156.191 1.00 109.90 ? 107 THR A N   1 
ATOM   304  C CA  . THR A 1 107 ? 147.620 168.202 155.956 1.00 109.90 ? 107 THR A CA  1 
ATOM   305  C C   . THR A 1 107 ? 147.169 168.803 154.634 1.00 109.90 ? 107 THR A C   1 
ATOM   306  O O   . THR A 1 107 ? 148.028 169.062 153.792 1.00 109.90 ? 107 THR A O   1 
ATOM   307  C CB  . THR A 1 107 ? 146.751 168.770 157.093 1.00 109.90 ? 107 THR A CB  1 
ATOM   308  O OG1 . THR A 1 107 ? 145.370 168.724 156.712 1.00 109.90 ? 107 THR A OG1 1 
ATOM   309  C CG2 . THR A 1 107 ? 147.141 170.208 157.394 1.00 109.90 ? 107 THR A CG2 1 
ATOM   310  N N   . ASN A 1 108 ? 145.867 168.996 154.445 1.00 105.47 ? 108 ASN A N   1 
ATOM   311  C CA  . ASN A 1 108 ? 145.338 169.475 153.169 1.00 105.47 ? 108 ASN A CA  1 
ATOM   312  C C   . ASN A 1 108 ? 145.203 168.207 152.324 1.00 105.47 ? 108 ASN A C   1 
ATOM   313  O O   . ASN A 1 108 ? 144.868 167.148 152.859 1.00 105.47 ? 108 ASN A O   1 
ATOM   314  C CB  . ASN A 1 108 ? 146.304 170.459 152.513 1.00 105.47 ? 108 ASN A CB  1 
ATOM   315  C CG  . ASN A 1 108 ? 145.590 171.526 151.706 1.00 105.47 ? 108 ASN A CG  1 
ATOM   316  O OD1 . ASN A 1 108 ? 146.218 172.293 150.978 1.00 105.47 ? 108 ASN A OD1 1 
ATOM   317  N ND2 . ASN A 1 108 ? 144.269 171.578 151.833 1.00 105.47 ? 108 ASN A ND2 1 
ATOM   318  N N   . VAL A 1 109 ? 145.433 168.276 151.015 1.00 99.43  ? 109 VAL A N   1 
ATOM   319  C CA  . VAL A 1 109 ? 145.366 167.026 150.264 1.00 99.43  ? 109 VAL A CA  1 
ATOM   320  C C   . VAL A 1 109 ? 146.642 166.973 149.428 1.00 99.43  ? 109 VAL A C   1 
ATOM   321  O O   . VAL A 1 109 ? 147.350 165.954 149.348 1.00 99.43  ? 109 VAL A O   1 
ATOM   322  C CB  . VAL A 1 109 ? 144.090 166.917 149.404 1.00 99.43  ? 109 VAL A CB  1 
ATOM   323  C CG1 . VAL A 1 109 ? 142.895 166.622 150.265 1.00 99.43  ? 109 VAL A CG1 1 
ATOM   324  C CG2 . VAL A 1 109 ? 143.830 168.202 148.686 1.00 99.43  ? 109 VAL A CG2 1 
ATOM   325  N N   . LEU A 1 110 ? 146.911 168.096 148.762 1.00 98.57  ? 110 LEU A N   1 
ATOM   326  C CA  . LEU A 1 110 ? 148.007 168.149 147.813 1.00 98.57  ? 110 LEU A CA  1 
ATOM   327  C C   . LEU A 1 110 ? 149.314 167.756 148.477 1.00 98.57  ? 110 LEU A C   1 
ATOM   328  O O   . LEU A 1 110 ? 150.238 167.293 147.807 1.00 98.57  ? 110 LEU A O   1 
ATOM   329  C CB  . LEU A 1 110 ? 148.115 169.540 147.203 1.00 98.57  ? 110 LEU A CB  1 
ATOM   330  C CG  . LEU A 1 110 ? 147.074 169.883 146.141 1.00 98.57  ? 110 LEU A CG  1 
ATOM   331  C CD1 . LEU A 1 110 ? 145.786 170.346 146.772 1.00 98.57  ? 110 LEU A CD1 1 
ATOM   332  C CD2 . LEU A 1 110 ? 147.597 170.936 145.213 1.00 98.57  ? 110 LEU A CD2 1 
ATOM   333  N N   . HIS A 1 111 ? 149.411 167.922 149.796 1.00 96.90  ? 111 HIS A N   1 
ATOM   334  C CA  . HIS A 1 111 ? 150.583 167.412 150.489 1.00 96.90  ? 111 HIS A CA  1 
ATOM   335  C C   . HIS A 1 111 ? 150.712 165.913 150.315 1.00 96.90  ? 111 HIS A C   1 
ATOM   336  O O   . HIS A 1 111 ? 151.785 165.416 149.960 1.00 96.90  ? 111 HIS A O   1 
ATOM   337  C CB  . HIS A 1 111 ? 150.535 167.739 151.970 1.00 96.90  ? 111 HIS A CB  1 
ATOM   338  C CG  . HIS A 1 111 ? 151.716 167.213 152.714 1.00 96.90  ? 111 HIS A CG  1 
ATOM   339  N ND1 . HIS A 1 111 ? 152.958 167.805 152.650 1.00 96.90  ? 111 HIS A ND1 1 
ATOM   340  C CD2 . HIS A 1 111 ? 151.859 166.119 153.495 1.00 96.90  ? 111 HIS A CD2 1 
ATOM   341  C CE1 . HIS A 1 111 ? 153.807 167.117 153.389 1.00 96.90  ? 111 HIS A CE1 1 
ATOM   342  N NE2 . HIS A 1 111 ? 153.166 166.087 153.912 1.00 96.90  ? 111 HIS A NE2 1 
ATOM   343  N N   . ARG A 1 112 ? 149.634 165.167 150.564 1.00 90.43  ? 112 ARG A N   1 
ATOM   344  C CA  . ARG A 1 112 ? 149.724 163.724 150.387 1.00 90.43  ? 112 ARG A CA  1 
ATOM   345  C C   . ARG A 1 112 ? 150.014 163.388 148.939 1.00 90.43  ? 112 ARG A C   1 
ATOM   346  O O   . ARG A 1 112 ? 150.554 162.319 148.641 1.00 90.43  ? 112 ARG A O   1 
ATOM   347  C CB  . ARG A 1 112 ? 148.445 163.019 150.838 1.00 90.43  ? 112 ARG A CB  1 
ATOM   348  C CG  . ARG A 1 112 ? 147.318 163.017 149.827 1.00 90.43  ? 112 ARG A CG  1 
ATOM   349  C CD  . ARG A 1 112 ? 146.237 162.044 150.231 1.00 90.43  ? 112 ARG A CD  1 
ATOM   350  N NE  . ARG A 1 112 ? 145.854 162.229 151.624 1.00 90.43  ? 112 ARG A NE  1 
ATOM   351  C CZ  . ARG A 1 112 ? 144.897 163.050 152.032 1.00 90.43  ? 112 ARG A CZ  1 
ATOM   352  N NH1 . ARG A 1 112 ? 144.225 163.770 151.151 1.00 90.43  ? 112 ARG A NH1 1 
ATOM   353  N NH2 . ARG A 1 112 ? 144.617 163.154 153.322 1.00 90.43  ? 112 ARG A NH2 1 
ATOM   354  N N   . PHE A 1 113 ? 149.670 164.289 148.022 1.00 85.71  ? 113 PHE A N   1 
ATOM   355  C CA  . PHE A 1 113 ? 149.966 163.970 146.627 1.00 85.71  ? 113 PHE A CA  1 
ATOM   356  C C   . PHE A 1 113 ? 151.392 164.309 146.205 1.00 85.71  ? 113 PHE A C   1 
ATOM   357  O O   . PHE A 1 113 ? 151.918 163.667 145.294 1.00 85.71  ? 113 PHE A O   1 
ATOM   358  C CB  . PHE A 1 113 ? 148.976 164.662 145.699 1.00 85.71  ? 113 PHE A CB  1 
ATOM   359  C CG  . PHE A 1 113 ? 147.839 163.788 145.293 1.00 85.71  ? 113 PHE A CG  1 
ATOM   360  C CD1 . PHE A 1 113 ? 147.802 163.225 144.038 1.00 85.71  ? 113 PHE A CD1 1 
ATOM   361  C CD2 . PHE A 1 113 ? 146.823 163.502 146.177 1.00 85.71  ? 113 PHE A CD2 1 
ATOM   362  C CE1 . PHE A 1 113 ? 146.766 162.413 143.668 1.00 85.71  ? 113 PHE A CE1 1 
ATOM   363  C CE2 . PHE A 1 113 ? 145.784 162.688 145.812 1.00 85.71  ? 113 PHE A CE2 1 
ATOM   364  C CZ  . PHE A 1 113 ? 145.755 162.144 144.556 1.00 85.71  ? 113 PHE A CZ  1 
ATOM   365  N N   . VAL A 1 114 ? 152.037 165.293 146.830 1.00 83.48  ? 114 VAL A N   1 
ATOM   366  C CA  . VAL A 1 114 ? 153.290 165.812 146.287 1.00 83.48  ? 114 VAL A CA  1 
ATOM   367  C C   . VAL A 1 114 ? 154.434 165.739 147.289 1.00 83.48  ? 114 VAL A C   1 
ATOM   368  O O   . VAL A 1 114 ? 155.473 166.378 147.096 1.00 83.48  ? 114 VAL A O   1 
ATOM   369  C CB  . VAL A 1 114 ? 153.119 167.260 145.794 1.00 83.48  ? 114 VAL A CB  1 
ATOM   370  C CG1 . VAL A 1 114 ? 151.908 167.377 144.900 1.00 83.48  ? 114 VAL A CG1 1 
ATOM   371  C CG2 . VAL A 1 114 ? 153.031 168.220 146.955 1.00 83.48  ? 114 VAL A CG2 1 
ATOM   372  N N   . ALA A 1 115 ? 154.273 164.962 148.353 1.00 79.39  ? 115 ALA A N   1 
ATOM   373  C CA  . ALA A 1 115 ? 155.364 164.811 149.310 1.00 79.39  ? 115 ALA A CA  1 
ATOM   374  C C   . ALA A 1 115 ? 155.267 163.490 150.056 1.00 79.39  ? 115 ALA A C   1 
ATOM   375  O O   . ALA A 1 115 ? 154.179 162.924 150.183 1.00 79.39  ? 115 ALA A O   1 
ATOM   376  C CB  . ALA A 1 115 ? 155.370 165.975 150.298 1.00 79.39  ? 115 ALA A CB  1 
ATOM   377  N N   . VAL A 1 116 ? 156.388 162.987 150.556 1.00 73.81  ? 116 VAL A N   1 
ATOM   378  C CA  . VAL A 1 116 ? 156.373 161.744 151.317 1.00 73.81  ? 116 VAL A CA  1 
ATOM   379  C C   . VAL A 1 116 ? 155.674 161.995 152.643 1.00 73.81  ? 116 VAL A C   1 
ATOM   380  O O   . VAL A 1 116 ? 155.979 162.961 153.351 1.00 73.81  ? 116 VAL A O   1 
ATOM   381  C CB  . VAL A 1 116 ? 157.795 161.205 151.518 1.00 73.81  ? 116 VAL A CB  1 
ATOM   382  C CG1 . VAL A 1 116 ? 158.328 160.681 150.220 1.00 73.81  ? 116 VAL A CG1 1 
ATOM   383  C CG2 . VAL A 1 116 ? 158.698 162.284 152.036 1.00 73.81  ? 116 VAL A CG2 1 
ATOM   384  N N   . SER A 1 117 ? 154.716 161.141 152.971 1.00 77.07  ? 117 SER A N   1 
ATOM   385  C CA  . SER A 1 117 ? 153.868 161.363 154.128 1.00 77.07  ? 117 SER A CA  1 
ATOM   386  C C   . SER A 1 117 ? 154.223 160.347 155.212 1.00 77.07  ? 117 SER A C   1 
ATOM   387  O O   . SER A 1 117 ? 155.161 159.564 155.058 1.00 77.07  ? 117 SER A O   1 
ATOM   388  C CB  . SER A 1 117 ? 152.400 161.305 153.704 1.00 77.07  ? 117 SER A CB  1 
ATOM   389  O OG  . SER A 1 117 ? 151.556 161.774 154.738 1.00 77.07  ? 117 SER A OG  1 
ATOM   390  N N   . TYR A 1 118 ? 153.489 160.367 156.322 1.00 74.52  ? 118 TYR A N   1 
ATOM   391  C CA  . TYR A 1 118 ? 153.662 159.439 157.439 1.00 74.52  ? 118 TYR A CA  1 
ATOM   392  C C   . TYR A 1 118 ? 154.981 159.640 158.166 1.00 74.52  ? 118 TYR A C   1 
ATOM   393  O O   . TYR A 1 118 ? 155.614 158.670 158.579 1.00 74.52  ? 118 TYR A O   1 
ATOM   394  C CB  . TYR A 1 118 ? 153.536 157.987 156.985 1.00 74.52  ? 118 TYR A CB  1 
ATOM   395  C CG  . TYR A 1 118 ? 152.296 157.714 156.187 1.00 74.52  ? 118 TYR A CG  1 
ATOM   396  C CD1 . TYR A 1 118 ? 151.049 157.759 156.771 1.00 74.52  ? 118 TYR A CD1 1 
ATOM   397  C CD2 . TYR A 1 118 ? 152.376 157.415 154.848 1.00 74.52  ? 118 TYR A CD2 1 
ATOM   398  C CE1 . TYR A 1 118 ? 149.919 157.509 156.038 1.00 74.52  ? 118 TYR A CE1 1 
ATOM   399  C CE2 . TYR A 1 118 ? 151.258 157.162 154.112 1.00 74.52  ? 118 TYR A CE2 1 
ATOM   400  C CZ  . TYR A 1 118 ? 150.030 157.210 154.707 1.00 74.52  ? 118 TYR A CZ  1 
ATOM   401  O OH  . TYR A 1 118 ? 148.910 156.957 153.956 1.00 74.52  ? 118 TYR A OH  1 
ATOM   402  N N   . GLN A 1 119 ? 155.412 160.885 158.340 1.00 79.98  ? 119 GLN A N   1 
ATOM   403  C CA  . GLN A 1 119 ? 156.591 161.155 159.149 1.00 79.98  ? 119 GLN A CA  1 
ATOM   404  C C   . GLN A 1 119 ? 156.335 160.773 160.599 1.00 79.98  ? 119 GLN A C   1 
ATOM   405  O O   . GLN A 1 119 ? 155.335 161.195 161.186 1.00 79.98  ? 119 GLN A O   1 
ATOM   406  C CB  . GLN A 1 119 ? 156.985 162.624 159.068 1.00 79.98  ? 119 GLN A CB  1 
ATOM   407  C CG  . GLN A 1 119 ? 158.147 162.980 159.965 1.00 79.98  ? 119 GLN A CG  1 
ATOM   408  C CD  . GLN A 1 119 ? 158.649 164.384 159.739 1.00 79.98  ? 119 GLN A CD  1 
ATOM   409  O OE1 . GLN A 1 119 ? 157.916 165.248 159.263 1.00 79.98  ? 119 GLN A OE1 1 
ATOM   410  N NE2 . GLN A 1 119 ? 159.907 164.624 160.087 1.00 79.98  ? 119 GLN A NE2 1 
ATOM   411  N N   . ILE A 1 120 ? 157.227 159.979 161.189 1.00 82.88  ? 120 ILE A N   1 
ATOM   412  C CA  . ILE A 1 120 ? 157.031 159.551 162.566 1.00 82.88  ? 120 ILE A CA  1 
ATOM   413  C C   . ILE A 1 120 ? 157.410 160.681 163.507 1.00 82.88  ? 120 ILE A C   1 
ATOM   414  O O   . ILE A 1 120 ? 158.593 160.987 163.698 1.00 82.88  ? 120 ILE A O   1 
ATOM   415  C CB  . ILE A 1 120 ? 157.839 158.279 162.852 1.00 82.88  ? 120 ILE A CB  1 
ATOM   416  C CG1 . ILE A 1 120 ? 157.284 157.113 162.041 1.00 82.88  ? 120 ILE A CG1 1 
ATOM   417  C CG2 . ILE A 1 120 ? 157.810 157.949 164.326 1.00 82.88  ? 120 ILE A CG2 1 
ATOM   418  C CD1 . ILE A 1 120 ? 155.831 156.844 162.298 1.00 82.88  ? 120 ILE A CD1 1 
ATOM   419  N N   . GLY A 1 121 ? 156.400 161.303 164.110 1.00 90.55  ? 121 GLY A N   1 
ATOM   420  C CA  . GLY A 1 121 ? 156.613 162.435 164.988 1.00 90.55  ? 121 GLY A CA  1 
ATOM   421  C C   . GLY A 1 121 ? 157.267 163.600 164.279 1.00 90.55  ? 121 GLY A C   1 
ATOM   422  O O   . GLY A 1 121 ? 156.769 164.076 163.256 1.00 90.55  ? 121 GLY A O   1 
ATOM   423  N N   . ASP A 1 122 ? 158.386 164.073 164.821 1.00 98.87  ? 122 ASP A N   1 
ATOM   424  C CA  . ASP A 1 122 ? 159.182 165.092 164.153 1.00 98.87  ? 122 ASP A CA  1 
ATOM   425  C C   . ASP A 1 122 ? 160.588 164.528 164.008 1.00 98.87  ? 122 ASP A C   1 
ATOM   426  O O   . ASP A 1 122 ? 161.576 165.162 164.385 1.00 98.87  ? 122 ASP A O   1 
ATOM   427  C CB  . ASP A 1 122 ? 159.161 166.405 164.940 1.00 98.87  ? 122 ASP A CB  1 
ATOM   428  C CG  . ASP A 1 122 ? 159.740 167.576 164.160 1.00 98.87  ? 122 ASP A CG  1 
ATOM   429  O OD1 . ASP A 1 122 ? 160.964 167.623 163.931 1.00 98.87  ? 122 ASP A OD1 1 
ATOM   430  O OD2 . ASP A 1 122 ? 158.953 168.461 163.765 1.00 98.87  ? 122 ASP A OD2 1 
ATOM   431  N N   . THR A 1 123 ? 160.676 163.304 163.498 1.00 89.40  ? 123 THR A N   1 
ATOM   432  C CA  . THR A 1 123 ? 161.952 162.619 163.388 1.00 89.40  ? 123 THR A CA  1 
ATOM   433  C C   . THR A 1 123 ? 162.226 162.358 161.912 1.00 89.40  ? 123 THR A C   1 
ATOM   434  O O   . THR A 1 123 ? 161.346 162.560 161.070 1.00 89.40  ? 123 THR A O   1 
ATOM   435  C CB  . THR A 1 123 ? 161.914 161.318 164.199 1.00 89.40  ? 123 THR A CB  1 
ATOM   436  O OG1 . THR A 1 123 ? 161.448 161.608 165.519 1.00 89.40  ? 123 THR A OG1 1 
ATOM   437  C CG2 . THR A 1 123 ? 163.299 160.713 164.338 1.00 89.40  ? 123 THR A CG2 1 
ATOM   438  N N   . ASN A 1 124 ? 163.436 161.917 161.581 1.00 80.61  ? 124 ASN A N   1 
ATOM   439  C CA  . ASN A 1 124 ? 163.735 161.510 160.219 1.00 80.61  ? 124 ASN A CA  1 
ATOM   440  C C   . ASN A 1 124 ? 163.427 160.027 160.083 1.00 80.61  ? 124 ASN A C   1 
ATOM   441  O O   . ASN A 1 124 ? 164.337 159.195 160.032 1.00 80.61  ? 124 ASN A O   1 
ATOM   442  C CB  . ASN A 1 124 ? 165.193 161.813 159.886 1.00 80.61  ? 124 ASN A CB  1 
ATOM   443  C CG  . ASN A 1 124 ? 165.562 161.417 158.483 1.00 80.61  ? 124 ASN A CG  1 
ATOM   444  O OD1 . ASN A 1 124 ? 166.170 160.374 158.260 1.00 80.61  ? 124 ASN A OD1 1 
ATOM   445  N ND2 . ASN A 1 124 ? 165.205 162.256 157.524 1.00 80.61  ? 124 ASN A ND2 1 
ATOM   446  N N   . ALA A 1 125 ? 162.140 159.689 160.049 1.00 76.97  ? 125 ALA A N   1 
ATOM   447  C CA  . ALA A 1 125 ? 161.698 158.305 159.903 1.00 76.97  ? 125 ALA A CA  1 
ATOM   448  C C   . ALA A 1 125 ? 160.264 158.332 159.410 1.00 76.97  ? 125 ALA A C   1 
ATOM   449  O O   . ALA A 1 125 ? 159.413 158.965 160.037 1.00 76.97  ? 125 ALA A O   1 
ATOM   450  C CB  . ALA A 1 125 ? 161.806 157.548 161.219 1.00 76.97  ? 125 ALA A CB  1 
ATOM   451  N N   . TYR A 1 126 ? 159.996 157.658 158.298 1.00 70.29  ? 126 TYR A N   1 
ATOM   452  C CA  . TYR A 1 126 ? 158.717 157.757 157.613 1.00 70.29  ? 126 TYR A CA  1 
ATOM   453  C C   . TYR A 1 126 ? 158.072 156.387 157.495 1.00 70.29  ? 126 TYR A C   1 
ATOM   454  O O   . TYR A 1 126 ? 158.754 155.399 157.222 1.00 70.29  ? 126 TYR A O   1 
ATOM   455  C CB  . TYR A 1 126 ? 158.901 158.377 156.233 1.00 70.29  ? 126 TYR A CB  1 
ATOM   456  C CG  . TYR A 1 126 ? 159.340 159.813 156.279 1.00 70.29  ? 126 TYR A CG  1 
ATOM   457  C CD1 . TYR A 1 126 ? 158.433 160.839 156.100 1.00 70.29  ? 126 TYR A CD1 1 
ATOM   458  C CD2 . TYR A 1 126 ? 160.662 160.143 156.489 1.00 70.29  ? 126 TYR A CD2 1 
ATOM   459  C CE1 . TYR A 1 126 ? 158.828 162.146 156.144 1.00 70.29  ? 126 TYR A CE1 1 
ATOM   460  C CE2 . TYR A 1 126 ? 161.065 161.451 156.532 1.00 70.29  ? 126 TYR A CE2 1 
ATOM   461  C CZ  . TYR A 1 126 ? 160.144 162.447 156.360 1.00 70.29  ? 126 TYR A CZ  1 
ATOM   462  O OH  . TYR A 1 126 ? 160.543 163.757 156.402 1.00 70.29  ? 126 TYR A OH  1 
ATOM   463  N N   . GLY A 1 127 ? 156.759 156.334 157.692 1.00 69.49  ? 127 GLY A N   1 
ATOM   464  C CA  . GLY A 1 127 ? 156.026 155.084 157.664 1.00 69.49  ? 127 GLY A CA  1 
ATOM   465  C C   . GLY A 1 127 ? 155.505 154.712 156.294 1.00 69.49  ? 127 GLY A C   1 
ATOM   466  O O   . GLY A 1 127 ? 156.046 155.156 155.283 1.00 69.49  ? 127 GLY A O   1 
ATOM   467  N N   . LYS A 1 128 ? 154.461 153.892 156.243 1.00 65.33  ? 128 LYS A N   1 
ATOM   468  C CA  . LYS A 1 128 ? 153.903 153.431 154.983 1.00 65.33  ? 128 LYS A CA  1 
ATOM   469  C C   . LYS A 1 128 ? 152.393 153.594 155.010 1.00 65.33  ? 128 LYS A C   1 
ATOM   470  O O   . LYS A 1 128 ? 151.779 153.557 156.076 1.00 65.33  ? 128 LYS A O   1 
ATOM   471  C CB  . LYS A 1 128 ? 154.252 151.968 154.721 1.00 65.33  ? 128 LYS A CB  1 
ATOM   472  C CG  . LYS A 1 128 ? 155.713 151.627 154.880 1.00 65.33  ? 128 LYS A CG  1 
ATOM   473  C CD  . LYS A 1 128 ? 155.929 150.151 154.662 1.00 65.33  ? 128 LYS A CD  1 
ATOM   474  C CE  . LYS A 1 128 ? 157.171 149.664 155.365 1.00 65.33  ? 128 LYS A CE  1 
ATOM   475  N NZ  . LYS A 1 128 ? 158.404 150.247 154.803 1.00 65.33  ? 128 LYS A NZ  1 
ATOM   476  N N   . GLY A 1 129 ? 151.798 153.770 153.840 1.00 71.28  ? 129 GLY A N   1 
ATOM   477  C CA  . GLY A 1 129 ? 150.356 153.878 153.774 1.00 71.28  ? 129 GLY A CA  1 
ATOM   478  C C   . GLY A 1 129 ? 149.884 154.138 152.363 1.00 71.28  ? 129 GLY A C   1 
ATOM   479  O O   . GLY A 1 129 ? 150.654 154.062 151.407 1.00 71.28  ? 129 GLY A O   1 
ATOM   480  N N   . ILE A 1 130 ? 148.592 154.449 152.245 1.00 74.23  ? 130 ILE A N   1 
ATOM   481  C CA  . ILE A 1 130 ? 147.993 154.738 150.944 1.00 74.23  ? 130 ILE A CA  1 
ATOM   482  C C   . ILE A 1 130 ? 148.527 156.018 150.318 1.00 74.23  ? 130 ILE A C   1 
ATOM   483  O O   . ILE A 1 130 ? 148.575 156.133 149.079 1.00 74.23  ? 130 ILE A O   1 
ATOM   484  C CB  . ILE A 1 130 ? 146.464 154.775 151.116 1.00 74.23  ? 130 ILE A CB  1 
ATOM   485  C CG1 . ILE A 1 130 ? 145.764 154.817 149.763 1.00 74.23  ? 130 ILE A CG1 1 
ATOM   486  C CG2 . ILE A 1 130 ? 146.044 155.937 151.990 1.00 74.23  ? 130 ILE A CG2 1 
ATOM   487  C CD1 . ILE A 1 130 ? 145.850 153.536 149.008 1.00 74.23  ? 130 ILE A CD1 1 
ATOM   488  N N   . ASN A 1 131 ? 148.948 156.984 151.129 1.00 75.89  ? 131 ASN A N   1 
ATOM   489  C CA  . ASN A 1 131 ? 149.562 158.176 150.573 1.00 75.89  ? 131 ASN A CA  1 
ATOM   490  C C   . ASN A 1 131 ? 150.814 157.858 149.773 1.00 75.89  ? 131 ASN A C   1 
ATOM   491  O O   . ASN A 1 131 ? 151.188 158.642 148.898 1.00 75.89  ? 131 ASN A O   1 
ATOM   492  C CB  . ASN A 1 131 ? 149.890 159.163 151.685 1.00 75.89  ? 131 ASN A CB  1 
ATOM   493  C CG  . ASN A 1 131 ? 148.654 159.772 152.290 1.00 75.89  ? 131 ASN A CG  1 
ATOM   494  O OD1 . ASN A 1 131 ? 147.549 159.569 151.793 1.00 75.89  ? 131 ASN A OD1 1 
ATOM   495  N ND2 . ASN A 1 131 ? 148.829 160.523 153.368 1.00 75.89  ? 131 ASN A ND2 1 
ATOM   496  N N   . ASP A 1 132 ? 151.455 156.720 150.039 1.00 71.78  ? 132 ASP A N   1 
ATOM   497  C CA  . ASP A 1 132 ? 152.540 156.264 149.180 1.00 71.78  ? 132 ASP A CA  1 
ATOM   498  C C   . ASP A 1 132 ? 152.038 155.975 147.775 1.00 71.78  ? 132 ASP A C   1 
ATOM   499  O O   . ASP A 1 132 ? 152.702 156.306 146.791 1.00 71.78  ? 132 ASP A O   1 
ATOM   500  C CB  . ASP A 1 132 ? 153.200 155.029 149.780 1.00 71.78  ? 132 ASP A CB  1 
ATOM   501  C CG  . ASP A 1 132 ? 154.006 155.348 151.010 1.00 71.78  ? 132 ASP A CG  1 
ATOM   502  O OD1 . ASP A 1 132 ? 153.746 156.390 151.641 1.00 71.78  ? 132 ASP A OD1 1 
ATOM   503  O OD2 . ASP A 1 132 ? 154.908 154.556 151.347 1.00 71.78  ? 132 ASP A OD2 1 
ATOM   504  N N   . LEU A 1 133 ? 150.869 155.347 147.657 1.00 75.47  ? 133 LEU A N   1 
ATOM   505  C CA  . LEU A 1 133 ? 150.285 155.140 146.338 1.00 75.47  ? 133 LEU A CA  1 
ATOM   506  C C   . LEU A 1 133 ? 149.961 156.464 145.671 1.00 75.47  ? 133 LEU A C   1 
ATOM   507  O O   . LEU A 1 133 ? 150.162 156.623 144.461 1.00 75.47  ? 133 LEU A O   1 
ATOM   508  C CB  . LEU A 1 133 ? 149.035 154.278 146.433 1.00 75.47  ? 133 LEU A CB  1 
ATOM   509  C CG  . LEU A 1 133 ? 149.313 152.790 146.342 1.00 75.47  ? 133 LEU A CG  1 
ATOM   510  C CD1 . LEU A 1 133 ? 148.041 152.006 146.523 1.00 75.47  ? 133 LEU A CD1 1 
ATOM   511  C CD2 . LEU A 1 133 ? 149.906 152.517 144.989 1.00 75.47  ? 133 LEU A CD2 1 
ATOM   512  N N   . CYS A 1 134 ? 149.455 157.430 146.437 1.00 78.95  ? 134 CYS A N   1 
ATOM   513  C CA  . CYS A 1 134 ? 149.194 158.735 145.835 1.00 78.95  ? 134 CYS A CA  1 
ATOM   514  C C   . CYS A 1 134 ? 150.476 159.383 145.321 1.00 78.95  ? 134 CYS A C   1 
ATOM   515  O O   . CYS A 1 134 ? 150.499 159.930 144.211 1.00 78.95  ? 134 CYS A O   1 
ATOM   516  C CB  . CYS A 1 134 ? 148.499 159.647 146.838 1.00 78.95  ? 134 CYS A CB  1 
ATOM   517  S SG  . CYS A 1 134 ? 146.827 159.122 147.257 1.00 78.95  ? 134 CYS A SG  1 
ATOM   518  N N   . PHE A 1 135 ? 151.547 159.319 146.105 1.00 72.56  ? 135 PHE A N   1 
ATOM   519  C CA  . PHE A 1 135 ? 152.845 159.839 145.695 1.00 72.56  ? 135 PHE A CA  1 
ATOM   520  C C   . PHE A 1 135 ? 153.367 159.149 144.445 1.00 72.56  ? 135 PHE A C   1 
ATOM   521  O O   . PHE A 1 135 ? 153.869 159.815 143.531 1.00 72.56  ? 135 PHE A O   1 
ATOM   522  C CB  . PHE A 1 135 ? 153.823 159.657 146.849 1.00 72.56  ? 135 PHE A CB  1 
ATOM   523  C CG  . PHE A 1 135 ? 155.206 160.147 146.577 1.00 72.56  ? 135 PHE A CG  1 
ATOM   524  C CD1 . PHE A 1 135 ? 155.577 161.423 146.923 1.00 72.56  ? 135 PHE A CD1 1 
ATOM   525  C CD2 . PHE A 1 135 ? 156.152 159.313 146.018 1.00 72.56  ? 135 PHE A CD2 1 
ATOM   526  C CE1 . PHE A 1 135 ? 156.852 161.858 146.699 1.00 72.56  ? 135 PHE A CE1 1 
ATOM   527  C CE2 . PHE A 1 135 ? 157.422 159.753 145.786 1.00 72.56  ? 135 PHE A CE2 1 
ATOM   528  C CZ  . PHE A 1 135 ? 157.775 161.024 146.127 1.00 72.56  ? 135 PHE A CZ  1 
ATOM   529  N N   . VAL A 1 136 ? 153.268 157.823 144.394 1.00 73.88  ? 136 VAL A N   1 
ATOM   530  C CA  . VAL A 1 136 ? 153.747 157.086 143.235 1.00 73.88  ? 136 VAL A CA  1 
ATOM   531  C C   . VAL A 1 136 ? 152.967 157.485 141.995 1.00 73.88  ? 136 VAL A C   1 
ATOM   532  O O   . VAL A 1 136 ? 153.547 157.685 140.929 1.00 73.88  ? 136 VAL A O   1 
ATOM   533  C CB  . VAL A 1 136 ? 153.669 155.574 143.492 1.00 73.88  ? 136 VAL A CB  1 
ATOM   534  C CG1 . VAL A 1 136 ? 153.858 154.816 142.208 1.00 73.88  ? 136 VAL A CG1 1 
ATOM   535  C CG2 . VAL A 1 136 ? 154.718 155.171 144.482 1.00 73.88  ? 136 VAL A CG2 1 
ATOM   536  N N   . PHE A 1 137 ? 151.646 157.616 142.111 1.00 79.37  ? 137 PHE A N   1 
ATOM   537  C CA  . PHE A 1 137 ? 150.850 158.069 140.975 1.00 79.37  ? 137 PHE A CA  1 
ATOM   538  C C   . PHE A 1 137 ? 151.288 159.448 140.501 1.00 79.37  ? 137 PHE A C   1 
ATOM   539  O O   . PHE A 1 137 ? 151.515 159.668 139.298 1.00 79.37  ? 137 PHE A O   1 
ATOM   540  C CB  . PHE A 1 137 ? 149.376 158.079 141.364 1.00 79.37  ? 137 PHE A CB  1 
ATOM   541  C CG  . PHE A 1 137 ? 148.484 158.721 140.348 1.00 79.37  ? 137 PHE A CG  1 
ATOM   542  C CD1 . PHE A 1 137 ? 148.128 158.052 139.194 1.00 79.37  ? 137 PHE A CD1 1 
ATOM   543  C CD2 . PHE A 1 137 ? 147.994 159.999 140.555 1.00 79.37  ? 137 PHE A CD2 1 
ATOM   544  C CE1 . PHE A 1 137 ? 147.310 158.645 138.264 1.00 79.37  ? 137 PHE A CE1 1 
ATOM   545  C CE2 . PHE A 1 137 ? 147.176 160.595 139.629 1.00 79.37  ? 137 PHE A CE2 1 
ATOM   546  C CZ  . PHE A 1 137 ? 146.832 159.919 138.482 1.00 79.37  ? 137 PHE A CZ  1 
ATOM   547  N N   . TYR A 1 138 ? 151.427 160.390 141.428 1.00 78.52  ? 138 TYR A N   1 
ATOM   548  C CA  . TYR A 1 138 ? 151.769 161.737 141.005 1.00 78.52  ? 138 TYR A CA  1 
ATOM   549  C C   . TYR A 1 138 ? 153.131 161.809 140.345 1.00 78.52  ? 138 TYR A C   1 
ATOM   550  O O   . TYR A 1 138 ? 153.305 162.540 139.362 1.00 78.52  ? 138 TYR A O   1 
ATOM   551  C CB  . TYR A 1 138 ? 151.734 162.696 142.171 1.00 78.52  ? 138 TYR A CB  1 
ATOM   552  C CG  . TYR A 1 138 ? 151.857 164.101 141.697 1.00 78.52  ? 138 TYR A CG  1 
ATOM   553  C CD1 . TYR A 1 138 ? 150.809 164.710 141.040 1.00 78.52  ? 138 TYR A CD1 1 
ATOM   554  C CD2 . TYR A 1 138 ? 153.021 164.814 141.881 1.00 78.52  ? 138 TYR A CD2 1 
ATOM   555  C CE1 . TYR A 1 138 ? 150.911 165.994 140.593 1.00 78.52  ? 138 TYR A CE1 1 
ATOM   556  C CE2 . TYR A 1 138 ? 153.133 166.101 141.439 1.00 78.52  ? 138 TYR A CE2 1 
ATOM   557  C CZ  . TYR A 1 138 ? 152.074 166.685 140.795 1.00 78.52  ? 138 TYR A CZ  1 
ATOM   558  O OH  . TYR A 1 138 ? 152.165 167.971 140.343 1.00 78.52  ? 138 TYR A OH  1 
ATOM   559  N N   . TYR A 1 139 ? 154.104 161.066 140.835 1.00 75.04  ? 139 TYR A N   1 
ATOM   560  C CA  . TYR A 1 139 ? 155.386 161.146 140.164 1.00 75.04  ? 139 TYR A CA  1 
ATOM   561  C C   . TYR A 1 139 ? 155.503 160.198 138.980 1.00 75.04  ? 139 TYR A C   1 
ATOM   562  O O   . TYR A 1 139 ? 156.422 160.359 138.181 1.00 75.04  ? 139 TYR A O   1 
ATOM   563  C CB  . TYR A 1 139 ? 156.503 160.946 141.170 1.00 75.04  ? 139 TYR A CB  1 
ATOM   564  C CG  . TYR A 1 139 ? 156.700 162.216 141.942 1.00 75.04  ? 139 TYR A CG  1 
ATOM   565  C CD1 . TYR A 1 139 ? 157.318 163.303 141.363 1.00 75.04  ? 139 TYR A CD1 1 
ATOM   566  C CD2 . TYR A 1 139 ? 156.203 162.354 143.217 1.00 75.04  ? 139 TYR A CD2 1 
ATOM   567  C CE1 . TYR A 1 139 ? 157.478 164.473 142.052 1.00 75.04  ? 139 TYR A CE1 1 
ATOM   568  C CE2 . TYR A 1 139 ? 156.355 163.522 143.912 1.00 75.04  ? 139 TYR A CE2 1 
ATOM   569  C CZ  . TYR A 1 139 ? 156.995 164.574 143.329 1.00 75.04  ? 139 TYR A CZ  1 
ATOM   570  O OH  . TYR A 1 139 ? 157.145 165.739 144.032 1.00 75.04  ? 139 TYR A OH  1 
ATOM   571  N N   . MET A 1 140 ? 154.562 159.276 138.788 1.00 78.71  ? 140 MET A N   1 
ATOM   572  C CA  . MET A 1 140 ? 154.383 158.714 137.456 1.00 78.71  ? 140 MET A CA  1 
ATOM   573  C C   . MET A 1 140 ? 154.034 159.810 136.470 1.00 78.71  ? 140 MET A C   1 
ATOM   574  O O   . MET A 1 140 ? 154.587 159.869 135.367 1.00 78.71  ? 140 MET A O   1 
ATOM   575  C CB  . MET A 1 140 ? 153.290 157.648 137.449 1.00 78.71  ? 140 MET A CB  1 
ATOM   576  C CG  . MET A 1 140 ? 153.600 156.399 138.215 1.00 78.71  ? 140 MET A CG  1 
ATOM   577  S SD  . MET A 1 140 ? 152.206 155.267 138.202 1.00 78.71  ? 140 MET A SD  1 
ATOM   578  C CE  . MET A 1 140 ? 152.226 154.746 136.499 1.00 78.71  ? 140 MET A CE  1 
ATOM   579  N N   . ILE A 1 141 ? 153.114 160.695 136.852 1.00 78.41  ? 141 ILE A N   1 
ATOM   580  C CA  . ILE A 1 141 ? 152.774 161.812 135.966 1.00 78.41  ? 141 ILE A CA  1 
ATOM   581  C C   . ILE A 1 141 ? 154.006 162.674 135.713 1.00 78.41  ? 141 ILE A C   1 
ATOM   582  O O   . ILE A 1 141 ? 154.299 163.069 134.574 1.00 78.41  ? 141 ILE A O   1 
ATOM   583  C CB  . ILE A 1 141 ? 151.620 162.637 136.555 1.00 78.41  ? 141 ILE A CB  1 
ATOM   584  C CG1 . ILE A 1 141 ? 150.466 161.721 136.942 1.00 78.41  ? 141 ILE A CG1 1 
ATOM   585  C CG2 . ILE A 1 141 ? 151.138 163.654 135.555 1.00 78.41  ? 141 ILE A CG2 1 
ATOM   586  C CD1 . ILE A 1 141 ? 149.928 160.926 135.790 1.00 78.41  ? 141 ILE A CD1 1 
ATOM   587  N N   . PHE A 1 142 ? 154.750 162.970 136.777 1.00 80.40  ? 142 PHE A N   1 
ATOM   588  C CA  . PHE A 1 142 ? 155.982 163.742 136.621 1.00 80.40  ? 142 PHE A CA  1 
ATOM   589  C C   . PHE A 1 142 ? 156.967 163.086 135.665 1.00 80.40  ? 142 PHE A C   1 
ATOM   590  O O   . PHE A 1 142 ? 157.505 163.760 134.785 1.00 80.40  ? 142 PHE A O   1 
ATOM   591  C CB  . PHE A 1 142 ? 156.672 163.947 137.962 1.00 80.40  ? 142 PHE A CB  1 
ATOM   592  C CG  . PHE A 1 142 ? 158.047 164.529 137.842 1.00 80.40  ? 142 PHE A CG  1 
ATOM   593  C CD1 . PHE A 1 142 ? 158.228 165.869 137.615 1.00 80.40  ? 142 PHE A CD1 1 
ATOM   594  C CD2 . PHE A 1 142 ? 159.160 163.722 137.944 1.00 80.40  ? 142 PHE A CD2 1 
ATOM   595  C CE1 . PHE A 1 142 ? 159.488 166.398 137.502 1.00 80.40  ? 142 PHE A CE1 1 
ATOM   596  C CE2 . PHE A 1 142 ? 160.423 164.244 137.829 1.00 80.40  ? 142 PHE A CE2 1 
ATOM   597  C CZ  . PHE A 1 142 ? 160.588 165.582 137.608 1.00 80.40  ? 142 PHE A CZ  1 
ATOM   598  N N   . PHE A 1 143 ? 157.248 161.796 135.839 1.00 79.46  ? 143 PHE A N   1 
ATOM   599  C CA  . PHE A 1 143 ? 158.238 161.144 134.995 1.00 79.46  ? 143 PHE A CA  1 
ATOM   600  C C   . PHE A 1 143 ? 157.758 161.017 133.562 1.00 79.46  ? 143 PHE A C   1 
ATOM   601  O O   . PHE A 1 143 ? 158.578 161.049 132.643 1.00 79.46  ? 143 PHE A O   1 
ATOM   602  C CB  . PHE A 1 143 ? 158.598 159.773 135.553 1.00 79.46  ? 143 PHE A CB  1 
ATOM   603  C CG  . PHE A 1 143 ? 159.572 159.824 136.688 1.00 79.46  ? 143 PHE A CG  1 
ATOM   604  C CD1 . PHE A 1 143 ? 160.832 160.343 136.506 1.00 79.46  ? 143 PHE A CD1 1 
ATOM   605  C CD2 . PHE A 1 143 ? 159.230 159.354 137.934 1.00 79.46  ? 143 PHE A CD2 1 
ATOM   606  C CE1 . PHE A 1 143 ? 161.720 160.394 137.545 1.00 79.46  ? 143 PHE A CE1 1 
ATOM   607  C CE2 . PHE A 1 143 ? 160.114 159.405 138.970 1.00 79.46  ? 143 PHE A CE2 1 
ATOM   608  C CZ  . PHE A 1 143 ? 161.357 159.923 138.776 1.00 79.46  ? 143 PHE A CZ  1 
ATOM   609  N N   . THR A 1 144 ? 156.449 160.878 133.346 1.00 85.38  ? 144 THR A N   1 
ATOM   610  C CA  . THR A 1 144 ? 155.928 160.957 131.989 1.00 85.38  ? 144 THR A CA  1 
ATOM   611  C C   . THR A 1 144 ? 156.189 162.312 131.360 1.00 85.38  ? 144 THR A C   1 
ATOM   612  O O   . THR A 1 144 ? 156.558 162.369 130.184 1.00 85.38  ? 144 THR A O   1 
ATOM   613  C CB  . THR A 1 144 ? 154.434 160.657 131.962 1.00 85.38  ? 144 THR A CB  1 
ATOM   614  O OG1 . THR A 1 144 ? 154.206 159.330 132.441 1.00 85.38  ? 144 THR A OG1 1 
ATOM   615  C CG2 . THR A 1 144 ? 153.900 160.762 130.553 1.00 85.38  ? 144 THR A CG2 1 
ATOM   616  N N   . PHE A 1 145 ? 156.012 163.399 132.104 1.00 91.21  ? 145 PHE A N   1 
ATOM   617  C CA  . PHE A 1 145 ? 156.459 164.681 131.568 1.00 91.21  ? 145 PHE A CA  1 
ATOM   618  C C   . PHE A 1 145 ? 157.947 164.700 131.270 1.00 91.21  ? 145 PHE A C   1 
ATOM   619  O O   . PHE A 1 145 ? 158.352 165.126 130.180 1.00 91.21  ? 145 PHE A O   1 
ATOM   620  C CB  . PHE A 1 145 ? 156.159 165.823 132.534 1.00 91.21  ? 145 PHE A CB  1 
ATOM   621  C CG  . PHE A 1 145 ? 157.143 166.954 132.444 1.00 91.21  ? 145 PHE A CG  1 
ATOM   622  C CD1 . PHE A 1 145 ? 157.112 167.836 131.391 1.00 91.21  ? 145 PHE A CD1 1 
ATOM   623  C CD2 . PHE A 1 145 ? 158.111 167.123 133.412 1.00 91.21  ? 145 PHE A CD2 1 
ATOM   624  C CE1 . PHE A 1 145 ? 158.020 168.863 131.310 1.00 91.21  ? 145 PHE A CE1 1 
ATOM   625  C CE2 . PHE A 1 145 ? 159.020 168.148 133.331 1.00 91.21  ? 145 PHE A CE2 1 
ATOM   626  C CZ  . PHE A 1 145 ? 158.975 169.017 132.280 1.00 91.21  ? 145 PHE A CZ  1 
ATOM   627  N N   . LEU A 1 146 ? 158.758 164.263 132.228 1.00 92.55  ? 146 LEU A N   1 
ATOM   628  C CA  . LEU A 1 146 ? 160.199 164.427 132.114 1.00 92.55  ? 146 LEU A CA  1 
ATOM   629  C C   . LEU A 1 146 ? 160.753 163.637 130.945 1.00 92.55  ? 146 LEU A C   1 
ATOM   630  O O   . LEU A 1 146 ? 161.619 164.129 130.218 1.00 92.55  ? 146 LEU A O   1 
ATOM   631  C CB  . LEU A 1 146 ? 160.885 164.004 133.407 1.00 92.55  ? 146 LEU A CB  1 
ATOM   632  C CG  . LEU A 1 146 ? 162.397 164.195 133.409 1.00 92.55  ? 146 LEU A CG  1 
ATOM   633  C CD1 . LEU A 1 146 ? 162.748 165.655 133.256 1.00 92.55  ? 146 LEU A CD1 1 
ATOM   634  C CD2 . LEU A 1 146 ? 162.980 163.642 134.681 1.00 92.55  ? 146 LEU A CD2 1 
ATOM   635  N N   . ARG A 1 147 ? 160.270 162.413 130.745 1.00 98.72  ? 147 ARG A N   1 
ATOM   636  C CA  . ARG A 1 147 ? 160.782 161.595 129.656 1.00 98.72  ? 147 ARG A CA  1 
ATOM   637  C C   . ARG A 1 147 ? 160.615 162.303 128.325 1.00 98.72  ? 147 ARG A C   1 
ATOM   638  O O   . ARG A 1 147 ? 161.585 162.493 127.591 1.00 98.72  ? 147 ARG A O   1 
ATOM   639  C CB  . ARG A 1 147 ? 160.075 160.247 129.631 1.00 98.72  ? 147 ARG A CB  1 
ATOM   640  C CG  . ARG A 1 147 ? 160.548 159.366 128.513 1.00 98.72  ? 147 ARG A CG  1 
ATOM   641  C CD  . ARG A 1 147 ? 160.045 157.954 128.666 1.00 98.72  ? 147 ARG A CD  1 
ATOM   642  N NE  . ARG A 1 147 ? 160.431 157.134 127.523 1.00 98.72  ? 147 ARG A NE  1 
ATOM   643  C CZ  . ARG A 1 147 ? 159.854 157.196 126.327 1.00 98.72  ? 147 ARG A CZ  1 
ATOM   644  N NH1 . ARG A 1 147 ? 160.277 156.413 125.345 1.00 98.72  ? 147 ARG A NH1 1 
ATOM   645  N NH2 . ARG A 1 147 ? 158.852 158.036 126.111 1.00 98.72  ? 147 ARG A NH2 1 
ATOM   646  N N   . GLU A 1 148 ? 159.399 162.749 128.017 1.00 105.22 ? 148 GLU A N   1 
ATOM   647  C CA  . GLU A 1 148 ? 159.152 163.397 126.734 1.00 105.22 ? 148 GLU A CA  1 
ATOM   648  C C   . GLU A 1 148 ? 159.915 164.708 126.613 1.00 105.22 ? 148 GLU A C   1 
ATOM   649  O O   . GLU A 1 148 ? 160.569 164.974 125.594 1.00 105.22 ? 148 GLU A O   1 
ATOM   650  C CB  . GLU A 1 148 ? 157.652 163.624 126.547 1.00 105.22 ? 148 GLU A CB  1 
ATOM   651  C CG  . GLU A 1 148 ? 156.785 162.466 127.010 1.00 105.22 ? 148 GLU A CG  1 
ATOM   652  C CD  . GLU A 1 148 ? 156.783 161.303 126.036 1.00 105.22 ? 148 GLU A CD  1 
ATOM   653  O OE1 . GLU A 1 148 ? 157.438 161.400 124.978 1.00 105.22 ? 148 GLU A OE1 1 
ATOM   654  O OE2 . GLU A 1 148 ? 156.118 160.289 126.329 1.00 105.22 ? 148 GLU A OE2 1 
ATOM   655  N N   . PHE A 1 149 ? 159.838 165.550 127.647 1.00 104.86 ? 149 PHE A N   1 
ATOM   656  C CA  . PHE A 1 149 ? 160.468 166.860 127.552 1.00 104.86 ? 149 PHE A CA  1 
ATOM   657  C C   . PHE A 1 149 ? 161.972 166.738 127.385 1.00 104.86 ? 149 PHE A C   1 
ATOM   658  O O   . PHE A 1 149 ? 162.557 167.321 126.460 1.00 104.86 ? 149 PHE A O   1 
ATOM   659  C CB  . PHE A 1 149 ? 160.148 167.688 128.789 1.00 104.86 ? 149 PHE A CB  1 
ATOM   660  C CG  . PHE A 1 149 ? 160.949 168.944 128.893 1.00 104.86 ? 149 PHE A CG  1 
ATOM   661  C CD1 . PHE A 1 149 ? 160.495 170.110 128.322 1.00 104.86 ? 149 PHE A CD1 1 
ATOM   662  C CD2 . PHE A 1 149 ? 162.157 168.958 129.563 1.00 104.86 ? 149 PHE A CD2 1 
ATOM   663  C CE1 . PHE A 1 149 ? 161.226 171.262 128.412 1.00 104.86 ? 149 PHE A CE1 1 
ATOM   664  C CE2 . PHE A 1 149 ? 162.895 170.107 129.652 1.00 104.86 ? 149 PHE A CE2 1 
ATOM   665  C CZ  . PHE A 1 149 ? 162.429 171.262 129.078 1.00 104.86 ? 149 PHE A CZ  1 
ATOM   666  N N   . LEU A 1 150 ? 162.623 166.002 128.280 1.00 108.93 ? 150 LEU A N   1 
ATOM   667  C CA  . LEU A 1 150 ? 164.049 165.795 128.129 1.00 108.93 ? 150 LEU A CA  1 
ATOM   668  C C   . LEU A 1 150 ? 164.344 165.181 126.777 1.00 108.93 ? 150 LEU A C   1 
ATOM   669  O O   . LEU A 1 150 ? 165.119 165.744 125.999 1.00 108.93 ? 150 LEU A O   1 
ATOM   670  C CB  . LEU A 1 150 ? 164.576 164.914 129.251 1.00 108.93 ? 150 LEU A CB  1 
ATOM   671  C CG  . LEU A 1 150 ? 166.073 164.689 129.124 1.00 108.93 ? 150 LEU A CG  1 
ATOM   672  C CD1 . LEU A 1 150 ? 166.819 165.912 129.616 1.00 108.93 ? 150 LEU A CD1 1 
ATOM   673  C CD2 . LEU A 1 150 ? 166.488 163.460 129.897 1.00 108.93 ? 150 LEU A CD2 1 
ATOM   674  N N   . MET A 1 151 ? 163.657 164.080 126.446 1.00 115.21 ? 151 MET A N   1 
ATOM   675  C CA  . MET A 1 151 ? 163.887 163.364 125.201 1.00 115.21 ? 151 MET A CA  1 
ATOM   676  C C   . MET A 1 151 ? 163.996 164.329 124.037 1.00 115.21 ? 151 MET A C   1 
ATOM   677  O O   . MET A 1 151 ? 165.101 164.598 123.549 1.00 115.21 ? 151 MET A O   1 
ATOM   678  C CB  . MET A 1 151 ? 162.741 162.379 124.970 1.00 115.21 ? 151 MET A CB  1 
ATOM   679  C CG  . MET A 1 151 ? 162.919 161.488 123.776 1.00 115.21 ? 151 MET A CG  1 
ATOM   680  S SD  . MET A 1 151 ? 164.338 160.404 123.963 1.00 115.21 ? 151 MET A SD  1 
ATOM   681  C CE  . MET A 1 151 ? 163.711 159.261 125.188 1.00 115.21 ? 151 MET A CE  1 
ATOM   682  N N   . ASP A 1 152 ? 162.889 164.990 123.689 1.00 114.84 ? 152 ASP A N   1 
ATOM   683  C CA  . ASP A 1 152 ? 162.960 165.847 122.512 1.00 114.84 ? 152 ASP A CA  1 
ATOM   684  C C   . ASP A 1 152 ? 163.931 166.995 122.758 1.00 114.84 ? 152 ASP A C   1 
ATOM   685  O O   . ASP A 1 152 ? 165.041 166.994 122.214 1.00 114.84 ? 152 ASP A O   1 
ATOM   686  C CB  . ASP A 1 152 ? 161.576 166.354 122.073 1.00 114.84 ? 152 ASP A CB  1 
ATOM   687  C CG  . ASP A 1 152 ? 160.897 167.231 123.096 1.00 114.84 ? 152 ASP A CG  1 
ATOM   688  O OD1 . ASP A 1 152 ? 161.459 167.433 124.179 1.00 114.84 ? 152 ASP A OD1 1 
ATOM   689  O OD2 . ASP A 1 152 ? 159.803 167.754 122.798 1.00 114.84 ? 152 ASP A OD2 1 
ATOM   690  N N   . VAL A 1 153 ? 163.594 167.893 123.687 1.00 114.26 ? 153 VAL A N   1 
ATOM   691  C CA  . VAL A 1 153 ? 164.210 169.214 123.695 1.00 114.26 ? 153 VAL A CA  1 
ATOM   692  C C   . VAL A 1 153 ? 165.705 169.127 123.970 1.00 114.26 ? 153 VAL A C   1 
ATOM   693  O O   . VAL A 1 153 ? 166.494 169.893 123.408 1.00 114.26 ? 153 VAL A O   1 
ATOM   694  C CB  . VAL A 1 153 ? 163.496 170.128 124.701 1.00 114.26 ? 153 VAL A CB  1 
ATOM   695  C CG1 . VAL A 1 153 ? 164.335 171.351 124.995 1.00 114.26 ? 153 VAL A CG1 1 
ATOM   696  C CG2 . VAL A 1 153 ? 162.149 170.534 124.148 1.00 114.26 ? 153 VAL A CG2 1 
ATOM   697  N N   . VAL A 1 154 ? 166.136 168.203 124.829 1.00 117.09 ? 154 VAL A N   1 
ATOM   698  C CA  . VAL A 1 154 ? 167.568 168.112 125.053 1.00 117.09 ? 154 VAL A CA  1 
ATOM   699  C C   . VAL A 1 154 ? 168.222 167.130 124.093 1.00 117.09 ? 154 VAL A C   1 
ATOM   700  O O   . VAL A 1 154 ? 169.188 167.490 123.415 1.00 117.09 ? 154 VAL A O   1 
ATOM   701  C CB  . VAL A 1 154 ? 167.871 167.746 126.511 1.00 117.09 ? 154 VAL A CB  1 
ATOM   702  C CG1 . VAL A 1 154 ? 169.359 167.553 126.692 1.00 117.09 ? 154 VAL A CG1 1 
ATOM   703  C CG2 . VAL A 1 154 ? 167.377 168.840 127.428 1.00 117.09 ? 154 VAL A CG2 1 
ATOM   704  N N   . ILE A 1 155 ? 167.753 165.882 124.016 1.00 119.31 ? 155 ILE A N   1 
ATOM   705  C CA  . ILE A 1 155 ? 168.564 164.937 123.272 1.00 119.31 ? 155 ILE A CA  1 
ATOM   706  C C   . ILE A 1 155 ? 168.518 165.208 121.775 1.00 119.31 ? 155 ILE A C   1 
ATOM   707  O O   . ILE A 1 155 ? 169.572 165.249 121.133 1.00 119.31 ? 155 ILE A O   1 
ATOM   708  C CB  . ILE A 1 155 ? 168.169 163.486 123.580 1.00 119.31 ? 155 ILE A CB  1 
ATOM   709  C CG1 . ILE A 1 155 ? 168.446 163.147 125.044 1.00 119.31 ? 155 ILE A CG1 1 
ATOM   710  C CG2 . ILE A 1 155 ? 168.963 162.559 122.700 1.00 119.31 ? 155 ILE A CG2 1 
ATOM   711  C CD1 . ILE A 1 155 ? 167.323 163.428 125.981 1.00 119.31 ? 155 ILE A CD1 1 
ATOM   712  N N   . ARG A 1 156 ? 167.330 165.412 121.182 1.00 122.65 ? 156 ARG A N   1 
ATOM   713  C CA  . ARG A 1 156 ? 167.321 165.472 119.723 1.00 122.65 ? 156 ARG A CA  1 
ATOM   714  C C   . ARG A 1 156 ? 168.182 166.615 119.189 1.00 122.65 ? 156 ARG A C   1 
ATOM   715  O O   . ARG A 1 156 ? 168.984 166.382 118.278 1.00 122.65 ? 156 ARG A O   1 
ATOM   716  C CB  . ARG A 1 156 ? 165.896 165.574 119.177 1.00 122.65 ? 156 ARG A CB  1 
ATOM   717  C CG  . ARG A 1 156 ? 165.167 164.250 119.080 1.00 122.65 ? 156 ARG A CG  1 
ATOM   718  C CD  . ARG A 1 156 ? 163.795 164.460 118.479 1.00 122.65 ? 156 ARG A CD  1 
ATOM   719  N NE  . ARG A 1 156 ? 163.063 163.213 118.297 1.00 122.65 ? 156 ARG A NE  1 
ATOM   720  C CZ  . ARG A 1 156 ? 163.078 162.502 117.175 1.00 122.65 ? 156 ARG A CZ  1 
ATOM   721  N NH1 . ARG A 1 156 ? 162.379 161.380 117.087 1.00 122.65 ? 156 ARG A NH1 1 
ATOM   722  N NH2 . ARG A 1 156 ? 163.792 162.913 116.139 1.00 122.65 ? 156 ARG A NH2 1 
ATOM   723  N N   . PRO A 1 157 ? 168.076 167.843 119.712 1.00 123.62 ? 157 PRO A N   1 
ATOM   724  C CA  . PRO A 1 157 ? 169.045 168.866 119.299 1.00 123.62 ? 157 PRO A CA  1 
ATOM   725  C C   . PRO A 1 157 ? 170.480 168.458 119.557 1.00 123.62 ? 157 PRO A C   1 
ATOM   726  O O   . PRO A 1 157 ? 171.346 168.724 118.720 1.00 123.62 ? 157 PRO A O   1 
ATOM   727  C CB  . PRO A 1 157 ? 168.639 170.086 120.134 1.00 123.62 ? 157 PRO A CB  1 
ATOM   728  C CG  . PRO A 1 157 ? 167.205 169.910 120.336 1.00 123.62 ? 157 PRO A CG  1 
ATOM   729  C CD  . PRO A 1 157 ? 167.024 168.438 120.550 1.00 123.62 ? 157 PRO A CD  1 
ATOM   730  N N   . PHE A 1 158 ? 170.758 167.801 120.681 1.00 122.91 ? 158 PHE A N   1 
ATOM   731  C CA  . PHE A 1 158 ? 172.104 167.294 120.918 1.00 122.91 ? 158 PHE A CA  1 
ATOM   732  C C   . PHE A 1 158 ? 172.422 166.136 119.984 1.00 122.91 ? 158 PHE A C   1 
ATOM   733  O O   . PHE A 1 158 ? 173.536 166.036 119.459 1.00 122.91 ? 158 PHE A O   1 
ATOM   734  C CB  . PHE A 1 158 ? 172.250 166.874 122.381 1.00 122.91 ? 158 PHE A CB  1 
ATOM   735  C CG  . PHE A 1 158 ? 173.480 166.061 122.666 1.00 122.91 ? 158 PHE A CG  1 
ATOM   736  C CD1 . PHE A 1 158 ? 174.681 166.678 122.962 1.00 122.91 ? 158 PHE A CD1 1 
ATOM   737  C CD2 . PHE A 1 158 ? 173.429 164.677 122.673 1.00 122.91 ? 158 PHE A CD2 1 
ATOM   738  C CE1 . PHE A 1 158 ? 175.811 165.932 123.234 1.00 122.91 ? 158 PHE A CE1 1 
ATOM   739  C CE2 . PHE A 1 158 ? 174.554 163.929 122.944 1.00 122.91 ? 158 PHE A CE2 1 
ATOM   740  C CZ  . PHE A 1 158 ? 175.745 164.556 123.224 1.00 122.91 ? 158 PHE A CZ  1 
ATOM   741  N N   . ALA A 1 159 ? 171.451 165.254 119.756 1.00 126.49 ? 159 ALA A N   1 
ATOM   742  C CA  . ALA A 1 159 ? 171.728 164.027 119.024 1.00 126.49 ? 159 ALA A CA  1 
ATOM   743  C C   . ALA A 1 159 ? 171.833 164.248 117.524 1.00 126.49 ? 159 ALA A C   1 
ATOM   744  O O   . ALA A 1 159 ? 172.273 163.343 116.807 1.00 126.49 ? 159 ALA A O   1 
ATOM   745  C CB  . ALA A 1 159 ? 170.655 162.983 119.325 1.00 126.49 ? 159 ALA A CB  1 
ATOM   746  N N   . ILE A 1 160 ? 171.420 165.409 117.023 1.00 130.26 ? 160 ILE A N   1 
ATOM   747  C CA  . ILE A 1 160 ? 171.625 165.723 115.612 1.00 130.26 ? 160 ILE A CA  1 
ATOM   748  C C   . ILE A 1 160 ? 172.418 167.016 115.501 1.00 130.26 ? 160 ILE A C   1 
ATOM   749  O O   . ILE A 1 160 ? 172.609 167.549 114.404 1.00 130.26 ? 160 ILE A O   1 
ATOM   750  C CB  . ILE A 1 160 ? 170.295 165.829 114.845 1.00 130.26 ? 160 ILE A CB  1 
ATOM   751  C CG1 . ILE A 1 160 ? 169.507 167.055 115.298 1.00 130.26 ? 160 ILE A CG1 1 
ATOM   752  C CG2 . ILE A 1 160 ? 169.469 164.572 115.035 1.00 130.26 ? 160 ILE A CG2 1 
ATOM   753  C CD1 . ILE A 1 160 ? 168.274 167.314 114.477 1.00 130.26 ? 160 ILE A CD1 1 
ATOM   754  N N   . ARG A 1 161 ? 172.887 167.528 116.635 1.00 133.03 ? 161 ARG A N   1 
ATOM   755  C CA  . ARG A 1 161 ? 173.655 168.763 116.643 1.00 133.03 ? 161 ARG A CA  1 
ATOM   756  C C   . ARG A 1 161 ? 175.071 168.562 116.132 1.00 133.03 ? 161 ARG A C   1 
ATOM   757  O O   . ARG A 1 161 ? 175.733 169.546 115.782 1.00 133.03 ? 161 ARG A O   1 
ATOM   758  C CB  . ARG A 1 161 ? 173.686 169.353 118.055 1.00 133.03 ? 161 ARG A CB  1 
ATOM   759  C CG  . ARG A 1 161 ? 174.179 170.790 118.140 1.00 133.03 ? 161 ARG A CG  1 
ATOM   760  C CD  . ARG A 1 161 ? 173.143 171.752 117.581 1.00 133.03 ? 161 ARG A CD  1 
ATOM   761  N NE  . ARG A 1 161 ? 173.634 173.125 117.524 1.00 133.03 ? 161 ARG A NE  1 
ATOM   762  C CZ  . ARG A 1 161 ? 174.341 173.624 116.516 1.00 133.03 ? 161 ARG A CZ  1 
ATOM   763  N NH1 . ARG A 1 161 ? 174.745 174.885 116.549 1.00 133.03 ? 161 ARG A NH1 1 
ATOM   764  N NH2 . ARG A 1 161 ? 174.644 172.863 115.474 1.00 133.03 ? 161 ARG A NH2 1 
ATOM   765  N N   . LEU A 1 162 ? 175.480 167.300 116.146 1.00 138.89 ? 162 LEU A N   1 
ATOM   766  C CA  . LEU A 1 162 ? 176.761 166.839 115.664 1.00 138.89 ? 162 LEU A CA  1 
ATOM   767  C C   . LEU A 1 162 ? 176.362 165.847 114.586 1.00 138.89 ? 162 LEU A C   1 
ATOM   768  O O   . LEU A 1 162 ? 177.116 165.592 113.647 1.00 138.89 ? 162 LEU A O   1 
ATOM   769  C CB  . LEU A 1 162 ? 177.543 166.141 116.774 1.00 138.89 ? 162 LEU A CB  1 
ATOM   770  C CG  . LEU A 1 162 ? 176.758 165.796 118.041 1.00 138.89 ? 162 LEU A CG  1 
ATOM   771  C CD1 . LEU A 1 162 ? 175.809 164.635 117.787 1.00 138.89 ? 162 LEU A CD1 1 
ATOM   772  C CD2 . LEU A 1 162 ? 177.703 165.480 119.190 1.00 138.89 ? 162 LEU A CD2 1 
ATOM   773  N N   . HIS A 1 163 ? 175.159 165.287 114.729 1.00 142.51 ? 163 HIS A N   1 
ATOM   774  C CA  . HIS A 1 163 ? 174.649 164.349 113.726 1.00 142.51 ? 163 HIS A CA  1 
ATOM   775  C C   . HIS A 1 163 ? 174.973 162.897 113.837 1.00 142.51 ? 163 HIS A C   1 
ATOM   776  O O   . HIS A 1 163 ? 176.036 162.503 114.219 1.00 142.51 ? 163 HIS A O   1 
ATOM   777  C CB  . HIS A 1 163 ? 174.968 164.790 112.304 1.00 142.51 ? 163 HIS A CB  1 
ATOM   778  C CG  . HIS A 1 163 ? 175.910 163.869 111.583 1.00 142.51 ? 163 HIS A CG  1 
ATOM   779  N ND1 . HIS A 1 163 ? 175.479 162.766 110.878 1.00 142.51 ? 163 HIS A ND1 1 
ATOM   780  C CD2 . HIS A 1 163 ? 177.256 163.895 111.440 1.00 142.51 ? 163 HIS A CD2 1 
ATOM   781  C CE1 . HIS A 1 163 ? 176.519 162.151 110.345 1.00 142.51 ? 163 HIS A CE1 1 
ATOM   782  N NE2 . HIS A 1 163 ? 177.611 162.814 110.671 1.00 142.51 ? 163 HIS A NE2 1 
ATOM   783  N N   . VAL A 1 164 ? 173.969 162.103 113.502 1.00 138.53 ? 164 VAL A N   1 
ATOM   784  C CA  . VAL A 1 164 ? 174.004 160.646 113.370 1.00 138.53 ? 164 VAL A CA  1 
ATOM   785  C C   . VAL A 1 164 ? 172.920 160.329 112.362 1.00 138.53 ? 164 VAL A C   1 
ATOM   786  O O   . VAL A 1 164 ? 171.862 159.788 112.680 1.00 138.53 ? 164 VAL A O   1 
ATOM   787  C CB  . VAL A 1 164 ? 173.645 159.850 114.602 1.00 138.53 ? 164 VAL A CB  1 
ATOM   788  C CG1 . VAL A 1 164 ? 174.631 158.723 114.774 1.00 138.53 ? 164 VAL A CG1 1 
ATOM   789  C CG2 . VAL A 1 164 ? 173.381 160.700 115.827 1.00 138.53 ? 164 VAL A CG2 1 
ATOM   790  N N   . THR A 1 165 ? 173.182 160.704 111.133 1.00 142.33 ? 165 THR A N   1 
ATOM   791  C CA  . THR A 1 165 ? 172.232 160.505 110.060 1.00 142.33 ? 165 THR A CA  1 
ATOM   792  C C   . THR A 1 165 ? 171.809 159.047 109.765 1.00 142.33 ? 165 THR A C   1 
ATOM   793  O O   . THR A 1 165 ? 172.540 158.242 109.178 1.00 142.33 ? 165 THR A O   1 
ATOM   794  C CB  . THR A 1 165 ? 172.726 161.170 108.757 1.00 142.33 ? 165 THR A CB  1 
ATOM   795  O OG1 . THR A 1 165 ? 173.574 162.283 109.067 1.00 142.33 ? 165 THR A OG1 1 
ATOM   796  C CG2 . THR A 1 165 ? 171.554 161.630 107.935 1.00 142.33 ? 165 THR A CG2 1 
ATOM   797  N N   . SER A 1 166 ? 170.616 158.708 110.205 1.00 139.81 ? 166 SER A N   1 
ATOM   798  C CA  . SER A 1 166 ? 170.055 157.420 109.958 1.00 139.81 ? 166 SER A CA  1 
ATOM   799  C C   . SER A 1 166 ? 168.621 157.735 110.260 1.00 139.81 ? 166 SER A C   1 
ATOM   800  O O   . SER A 1 166 ? 168.036 158.592 109.640 1.00 139.81 ? 166 SER A O   1 
ATOM   801  C CB  . SER A 1 166 ? 170.607 156.358 110.915 1.00 139.81 ? 166 SER A CB  1 
ATOM   802  O OG  . SER A 1 166 ? 171.950 155.976 110.633 1.00 139.81 ? 166 SER A OG  1 
ATOM   803  N N   . LYS A 1 167 ? 168.041 156.975 111.177 1.00 136.97 ? 167 LYS A N   1 
ATOM   804  C CA  . LYS A 1 167 ? 166.656 157.133 111.589 1.00 136.97 ? 167 LYS A CA  1 
ATOM   805  C C   . LYS A 1 167 ? 166.588 156.285 112.835 1.00 136.97 ? 167 LYS A C   1 
ATOM   806  O O   . LYS A 1 167 ? 166.601 156.802 113.952 1.00 136.97 ? 167 LYS A O   1 
ATOM   807  C CB  . LYS A 1 167 ? 165.704 156.597 110.522 1.00 136.97 ? 167 LYS A CB  1 
ATOM   808  C CG  . LYS A 1 167 ? 164.384 156.080 111.070 1.00 136.97 ? 167 LYS A CG  1 
ATOM   809  C CD  . LYS A 1 167 ? 163.555 157.206 111.666 1.00 136.97 ? 167 LYS A CD  1 
ATOM   810  C CE  . LYS A 1 167 ? 162.067 156.932 111.522 1.00 136.97 ? 167 LYS A CE  1 
ATOM   811  N NZ  . LYS A 1 167 ? 161.271 158.190 111.480 1.00 136.97 ? 167 LYS A NZ  1 
ATOM   812  N N   . HIS A 1 168 ? 166.515 154.974 112.645 1.00 135.05 ? 168 HIS A N   1 
ATOM   813  C CA  . HIS A 1 168 ? 166.550 154.079 113.793 1.00 135.05 ? 168 HIS A CA  1 
ATOM   814  C C   . HIS A 1 168 ? 167.797 154.338 114.614 1.00 135.05 ? 168 HIS A C   1 
ATOM   815  O O   . HIS A 1 168 ? 167.790 154.208 115.845 1.00 135.05 ? 168 HIS A O   1 
ATOM   816  C CB  . HIS A 1 168 ? 166.492 152.629 113.318 1.00 135.05 ? 168 HIS A CB  1 
ATOM   817  C CG  . HIS A 1 168 ? 166.760 151.628 114.395 1.00 135.05 ? 168 HIS A CG  1 
ATOM   818  N ND1 . HIS A 1 168 ? 167.987 151.024 114.558 1.00 135.05 ? 168 HIS A ND1 1 
ATOM   819  C CD2 . HIS A 1 168 ? 165.960 151.123 115.361 1.00 135.05 ? 168 HIS A CD2 1 
ATOM   820  C CE1 . HIS A 1 168 ? 167.933 150.192 115.582 1.00 135.05 ? 168 HIS A CE1 1 
ATOM   821  N NE2 . HIS A 1 168 ? 166.713 150.232 116.086 1.00 135.05 ? 168 HIS A NE2 1 
ATOM   822  N N   . ARG A 1 169 ? 168.877 154.719 113.937 1.00 134.34 ? 169 ARG A N   1 
ATOM   823  C CA  . ARG A 1 169 ? 170.079 155.162 114.617 1.00 134.34 ? 169 ARG A CA  1 
ATOM   824  C C   . ARG A 1 169 ? 169.741 156.287 115.585 1.00 134.34 ? 169 ARG A C   1 
ATOM   825  O O   . ARG A 1 169 ? 170.096 156.228 116.764 1.00 134.34 ? 169 ARG A O   1 
ATOM   826  C CB  . ARG A 1 169 ? 171.108 155.605 113.575 1.00 134.34 ? 169 ARG A CB  1 
ATOM   827  C CG  . ARG A 1 169 ? 172.540 155.626 114.046 1.00 134.34 ? 169 ARG A CG  1 
ATOM   828  C CD  . ARG A 1 169 ? 173.456 156.009 112.896 1.00 134.34 ? 169 ARG A CD  1 
ATOM   829  N NE  . ARG A 1 169 ? 174.868 155.856 113.236 1.00 134.34 ? 169 ARG A NE  1 
ATOM   830  C CZ  . ARG A 1 169 ? 175.869 156.132 112.407 1.00 134.34 ? 169 ARG A CZ  1 
ATOM   831  N NH1 . ARG A 1 169 ? 177.122 155.957 112.798 1.00 134.34 ? 169 ARG A NH1 1 
ATOM   832  N NH2 . ARG A 1 169 ? 175.617 156.583 111.185 1.00 134.34 ? 169 ARG A NH2 1 
ATOM   833  N N   . ILE A 1 170 ? 169.001 157.298 115.116 1.00 130.80 ? 170 ILE A N   1 
ATOM   834  C CA  . ILE A 1 170 ? 168.674 158.430 115.982 1.00 130.80 ? 170 ILE A CA  1 
ATOM   835  C C   . ILE A 1 170 ? 167.657 158.042 117.047 1.00 130.80 ? 170 ILE A C   1 
ATOM   836  O O   . ILE A 1 170 ? 167.718 158.546 118.179 1.00 130.80 ? 170 ILE A O   1 
ATOM   837  C CB  . ILE A 1 170 ? 168.204 159.649 115.162 1.00 130.80 ? 170 ILE A CB  1 
ATOM   838  C CG1 . ILE A 1 170 ? 168.313 160.909 116.015 1.00 130.80 ? 170 ILE A CG1 1 
ATOM   839  C CG2 . ILE A 1 170 ? 166.779 159.498 114.697 1.00 130.80 ? 170 ILE A CG2 1 
ATOM   840  C CD1 . ILE A 1 170 ? 169.719 161.234 116.421 1.00 130.80 ? 170 ILE A CD1 1 
ATOM   841  N N   . LYS A 1 171 ? 166.788 157.090 116.722 1.00 127.56 ? 171 LYS A N   1 
ATOM   842  C CA  . LYS A 1 171 ? 165.798 156.609 117.675 1.00 127.56 ? 171 LYS A CA  1 
ATOM   843  C C   . LYS A 1 171 ? 166.489 155.944 118.868 1.00 127.56 ? 171 LYS A C   1 
ATOM   844  O O   . LYS A 1 171 ? 166.094 156.148 120.016 1.00 127.56 ? 171 LYS A O   1 
ATOM   845  C CB  . LYS A 1 171 ? 164.839 155.624 117.004 1.00 127.56 ? 171 LYS A CB  1 
ATOM   846  C CG  . LYS A 1 171 ? 163.467 155.552 117.654 1.00 127.56 ? 171 LYS A CG  1 
ATOM   847  C CD  . LYS A 1 171 ? 163.319 154.292 118.491 1.00 127.56 ? 171 LYS A CD  1 
ATOM   848  C CE  . LYS A 1 171 ? 162.168 154.415 119.475 1.00 127.56 ? 171 LYS A CE  1 
ATOM   849  N NZ  . LYS A 1 171 ? 162.306 153.469 120.616 1.00 127.56 ? 171 LYS A NZ  1 
ATOM   850  N N   . ARG A 1 172 ? 167.522 155.150 118.590 1.00 126.40 ? 172 ARG A N   1 
ATOM   851  C CA  . ARG A 1 172 ? 168.268 154.467 119.635 1.00 126.40 ? 172 ARG A CA  1 
ATOM   852  C C   . ARG A 1 172 ? 169.199 155.423 120.362 1.00 126.40 ? 172 ARG A C   1 
ATOM   853  O O   . ARG A 1 172 ? 169.386 155.309 121.575 1.00 126.40 ? 172 ARG A O   1 
ATOM   854  C CB  . ARG A 1 172 ? 169.024 153.283 119.046 1.00 126.40 ? 172 ARG A CB  1 
ATOM   855  C CG  . ARG A 1 172 ? 168.080 152.193 118.598 1.00 126.40 ? 172 ARG A CG  1 
ATOM   856  C CD  . ARG A 1 172 ? 167.323 151.626 119.788 1.00 126.40 ? 172 ARG A CD  1 
ATOM   857  N NE  . ARG A 1 172 ? 166.119 150.907 119.387 1.00 126.40 ? 172 ARG A NE  1 
ATOM   858  C CZ  . ARG A 1 172 ? 166.095 149.625 119.037 1.00 126.40 ? 172 ARG A CZ  1 
ATOM   859  N NH1 . ARG A 1 172 ? 164.953 149.051 118.688 1.00 126.40 ? 172 ARG A NH1 1 
ATOM   860  N NH2 . ARG A 1 172 ? 167.215 148.920 119.023 1.00 126.40 ? 172 ARG A NH2 1 
ATOM   861  N N   . ILE A 1 173 ? 169.782 156.389 119.645 1.00 122.66 ? 173 ILE A N   1 
ATOM   862  C CA  . ILE A 1 173 ? 170.576 157.400 120.338 1.00 122.66 ? 173 ILE A CA  1 
ATOM   863  C C   . ILE A 1 173 ? 169.752 158.121 121.380 1.00 122.66 ? 173 ILE A C   1 
ATOM   864  O O   . ILE A 1 173 ? 170.174 158.234 122.531 1.00 122.66 ? 173 ILE A O   1 
ATOM   865  C CB  . ILE A 1 173 ? 171.197 158.411 119.362 1.00 122.66 ? 173 ILE A CB  1 
ATOM   866  C CG1 . ILE A 1 173 ? 172.111 157.707 118.384 1.00 122.66 ? 173 ILE A CG1 1 
ATOM   867  C CG2 . ILE A 1 173 ? 171.956 159.478 120.126 1.00 122.66 ? 173 ILE A CG2 1 
ATOM   868  C CD1 . ILE A 1 173 ? 173.115 156.868 119.067 1.00 122.66 ? 173 ILE A CD1 1 
ATOM   869  N N   . MET A 1 174 ? 168.578 158.626 121.007 1.00 120.15 ? 174 MET A N   1 
ATOM   870  C CA  . MET A 1 174 ? 167.818 159.404 121.976 1.00 120.15 ? 174 MET A CA  1 
ATOM   871  C C   . MET A 1 174 ? 167.349 158.540 123.142 1.00 120.15 ? 174 MET A C   1 
ATOM   872  O O   . MET A 1 174 ? 167.434 158.962 124.303 1.00 120.15 ? 174 MET A O   1 
ATOM   873  C CB  . MET A 1 174 ? 166.659 160.126 121.279 1.00 120.15 ? 174 MET A CB  1 
ATOM   874  C CG  . MET A 1 174 ? 165.589 159.240 120.689 1.00 120.15 ? 174 MET A CG  1 
ATOM   875  S SD  . MET A 1 174 ? 164.304 160.180 119.849 1.00 120.15 ? 174 MET A SD  1 
ATOM   876  C CE  . MET A 1 174 ? 163.241 158.861 119.267 1.00 120.15 ? 174 MET A CE  1 
ATOM   877  N N   . GLU A 1 175 ? 166.914 157.310 122.864 1.00 114.63 ? 175 GLU A N   1 
ATOM   878  C CA  . GLU A 1 175 ? 166.475 156.431 123.943 1.00 114.63 ? 175 GLU A CA  1 
ATOM   879  C C   . GLU A 1 175 ? 167.617 156.103 124.900 1.00 114.63 ? 175 GLU A C   1 
ATOM   880  O O   . GLU A 1 175 ? 167.444 156.136 126.125 1.00 114.63 ? 175 GLU A O   1 
ATOM   881  C CB  . GLU A 1 175 ? 165.873 155.159 123.354 1.00 114.63 ? 175 GLU A CB  1 
ATOM   882  C CG  . GLU A 1 175 ? 165.228 154.252 124.369 1.00 114.63 ? 175 GLU A CG  1 
ATOM   883  C CD  . GLU A 1 175 ? 165.074 152.838 123.858 1.00 114.63 ? 175 GLU A CD  1 
ATOM   884  O OE1 . GLU A 1 175 ? 164.205 152.111 124.381 1.00 114.63 ? 175 GLU A OE1 1 
ATOM   885  O OE2 . GLU A 1 175 ? 165.814 152.455 122.930 1.00 114.63 ? 175 GLU A OE2 1 
ATOM   886  N N   . GLN A 1 176 ? 168.805 155.811 124.368 1.00 111.01 ? 176 GLN A N   1 
ATOM   887  C CA  . GLN A 1 176 ? 169.918 155.438 125.230 1.00 111.01 ? 176 GLN A CA  1 
ATOM   888  C C   . GLN A 1 176 ? 170.515 156.649 125.934 1.00 111.01 ? 176 GLN A C   1 
ATOM   889  O O   . GLN A 1 176 ? 171.067 156.513 127.030 1.00 111.01 ? 176 GLN A O   1 
ATOM   890  C CB  . GLN A 1 176 ? 170.984 154.715 124.419 1.00 111.01 ? 176 GLN A CB  1 
ATOM   891  C CG  . GLN A 1 176 ? 170.507 153.397 123.859 1.00 111.01 ? 176 GLN A CG  1 
ATOM   892  C CD  . GLN A 1 176 ? 170.130 152.406 124.928 1.00 111.01 ? 176 GLN A CD  1 
ATOM   893  O OE1 . GLN A 1 176 ? 168.954 152.104 125.117 1.00 111.01 ? 176 GLN A OE1 1 
ATOM   894  N NE2 . GLN A 1 176 ? 171.125 151.881 125.627 1.00 111.01 ? 176 GLN A NE2 1 
ATOM   895  N N   . MET A 1 177 ? 170.431 157.835 125.327 1.00 111.89 ? 177 MET A N   1 
ATOM   896  C CA  . MET A 1 177 ? 170.791 159.049 126.051 1.00 111.89 ? 177 MET A CA  1 
ATOM   897  C C   . MET A 1 177 ? 169.870 159.273 127.237 1.00 111.89 ? 177 MET A C   1 
ATOM   898  O O   . MET A 1 177 ? 170.326 159.653 128.319 1.00 111.89 ? 177 MET A O   1 
ATOM   899  C CB  . MET A 1 177 ? 170.751 160.271 125.139 1.00 111.89 ? 177 MET A CB  1 
ATOM   900  C CG  . MET A 1 177 ? 171.757 160.324 124.012 1.00 111.89 ? 177 MET A CG  1 
ATOM   901  S SD  . MET A 1 177 ? 173.457 160.405 124.582 1.00 111.89 ? 177 MET A SD  1 
ATOM   902  C CE  . MET A 1 177 ? 174.312 160.227 123.024 1.00 111.89 ? 177 MET A CE  1 
ATOM   903  N N   . TYR A 1 178 ? 168.568 159.064 127.060 1.00 100.42 ? 178 TYR A N   1 
ATOM   904  C CA  . TYR A 1 178 ? 167.708 159.170 128.230 1.00 100.42 ? 178 TYR A CA  1 
ATOM   905  C C   . TYR A 1 178 ? 168.077 158.114 129.257 1.00 100.42 ? 178 TYR A C   1 
ATOM   906  O O   . TYR A 1 178 ? 168.067 158.381 130.466 1.00 100.42 ? 178 TYR A O   1 
ATOM   907  C CB  . TYR A 1 178 ? 166.237 159.053 127.854 1.00 100.42 ? 178 TYR A CB  1 
ATOM   908  C CG  . TYR A 1 178 ? 165.345 159.108 129.064 1.00 100.42 ? 178 TYR A CG  1 
ATOM   909  C CD1 . TYR A 1 178 ? 164.574 158.022 129.433 1.00 100.42 ? 178 TYR A CD1 1 
ATOM   910  C CD2 . TYR A 1 178 ? 165.300 160.241 129.854 1.00 100.42 ? 178 TYR A CD2 1 
ATOM   911  C CE1 . TYR A 1 178 ? 163.768 158.072 130.545 1.00 100.42 ? 178 TYR A CE1 1 
ATOM   912  C CE2 . TYR A 1 178 ? 164.504 160.300 130.969 1.00 100.42 ? 178 TYR A CE2 1 
ATOM   913  C CZ  . TYR A 1 178 ? 163.737 159.215 131.311 1.00 100.42 ? 178 TYR A CZ  1 
ATOM   914  O OH  . TYR A 1 178 ? 162.935 159.271 132.425 1.00 100.42 ? 178 TYR A OH  1 
ATOM   915  N N   . ALA A 1 179 ? 168.409 156.908 128.792 1.00 98.26  ? 179 ALA A N   1 
ATOM   916  C CA  . ALA A 1 179 ? 168.835 155.861 129.712 1.00 98.26  ? 179 ALA A CA  1 
ATOM   917  C C   . ALA A 1 179 ? 170.010 156.319 130.556 1.00 98.26  ? 179 ALA A C   1 
ATOM   918  O O   . ALA A 1 179 ? 169.966 156.240 131.791 1.00 98.26  ? 179 ALA A O   1 
ATOM   919  C CB  . ALA A 1 179 ? 169.191 154.591 128.947 1.00 98.26  ? 179 ALA A CB  1 
ATOM   920  N N   . ILE A 1 180 ? 171.057 156.823 129.908 1.00 97.34  ? 180 ILE A N   1 
ATOM   921  C CA  . ILE A 1 180 ? 172.224 157.256 130.658 1.00 97.34  ? 180 ILE A CA  1 
ATOM   922  C C   . ILE A 1 180 ? 171.874 158.417 131.566 1.00 97.34  ? 180 ILE A C   1 
ATOM   923  O O   . ILE A 1 180 ? 172.411 158.518 132.668 1.00 97.34  ? 180 ILE A O   1 
ATOM   924  C CB  . ILE A 1 180 ? 173.403 157.604 129.734 1.00 97.34  ? 180 ILE A CB  1 
ATOM   925  C CG1 . ILE A 1 180 ? 174.640 157.880 130.573 1.00 97.34  ? 180 ILE A CG1 1 
ATOM   926  C CG2 . ILE A 1 180 ? 173.132 158.819 128.907 1.00 97.34  ? 180 ILE A CG2 1 
ATOM   927  C CD1 . ILE A 1 180 ? 175.843 158.118 129.755 1.00 97.34  ? 180 ILE A CD1 1 
ATOM   928  N N   . PHE A 1 181 ? 170.961 159.298 131.153 1.00 98.53  ? 181 PHE A N   1 
ATOM   929  C CA  . PHE A 1 181 ? 170.630 160.420 132.022 1.00 98.53  ? 181 PHE A CA  1 
ATOM   930  C C   . PHE A 1 181 ? 169.978 159.944 133.309 1.00 98.53  ? 181 PHE A C   1 
ATOM   931  O O   . PHE A 1 181 ? 170.440 160.282 134.409 1.00 98.53  ? 181 PHE A O   1 
ATOM   932  C CB  . PHE A 1 181 ? 169.717 161.411 131.309 1.00 98.53  ? 181 PHE A CB  1 
ATOM   933  C CG  . PHE A 1 181 ? 169.102 162.432 132.225 1.00 98.53  ? 181 PHE A CG  1 
ATOM   934  C CD1 . PHE A 1 181 ? 167.897 162.189 132.862 1.00 98.53  ? 181 PHE A CD1 1 
ATOM   935  C CD2 . PHE A 1 181 ? 169.732 163.640 132.448 1.00 98.53  ? 181 PHE A CD2 1 
ATOM   936  C CE1 . PHE A 1 181 ? 167.341 163.128 133.700 1.00 98.53  ? 181 PHE A CE1 1 
ATOM   937  C CE2 . PHE A 1 181 ? 169.175 164.585 133.285 1.00 98.53  ? 181 PHE A CE2 1 
ATOM   938  C CZ  . PHE A 1 181 ? 167.979 164.326 133.911 1.00 98.53  ? 181 PHE A CZ  1 
ATOM   939  N N   . TYR A 1 182 ? 168.908 159.148 133.207 1.00 92.34  ? 182 TYR A N   1 
ATOM   940  C CA  . TYR A 1 182 ? 168.250 158.827 134.467 1.00 92.34  ? 182 TYR A CA  1 
ATOM   941  C C   . TYR A 1 182 ? 169.100 157.900 135.300 1.00 92.34  ? 182 TYR A C   1 
ATOM   942  O O   . TYR A 1 182 ? 169.064 157.985 136.527 1.00 92.34  ? 182 TYR A O   1 
ATOM   943  C CB  . TYR A 1 182 ? 166.864 158.193 134.332 1.00 92.34  ? 182 TYR A CB  1 
ATOM   944  C CG  . TYR A 1 182 ? 166.755 156.841 133.679 1.00 92.34  ? 182 TYR A CG  1 
ATOM   945  C CD1 . TYR A 1 182 ? 166.558 156.719 132.325 1.00 92.34  ? 182 TYR A CD1 1 
ATOM   946  C CD2 . TYR A 1 182 ? 166.848 155.680 134.433 1.00 92.34  ? 182 TYR A CD2 1 
ATOM   947  C CE1 . TYR A 1 182 ? 166.422 155.490 131.736 1.00 92.34  ? 182 TYR A CE1 1 
ATOM   948  C CE2 . TYR A 1 182 ? 166.738 154.439 133.842 1.00 92.34  ? 182 TYR A CE2 1 
ATOM   949  C CZ  . TYR A 1 182 ? 166.531 154.355 132.483 1.00 92.34  ? 182 TYR A CZ  1 
ATOM   950  O OH  . TYR A 1 182 ? 166.414 153.140 131.849 1.00 92.34  ? 182 TYR A OH  1 
ATOM   951  N N   . THR A 1 183 ? 169.877 157.022 134.667 1.00 89.69  ? 183 THR A N   1 
ATOM   952  C CA  . THR A 1 183 ? 170.721 156.148 135.459 1.00 89.69  ? 183 THR A CA  1 
ATOM   953  C C   . THR A 1 183 ? 171.872 156.898 136.106 1.00 89.69  ? 183 THR A C   1 
ATOM   954  O O   . THR A 1 183 ? 172.257 156.565 137.226 1.00 89.69  ? 183 THR A O   1 
ATOM   955  C CB  . THR A 1 183 ? 171.247 155.013 134.603 1.00 89.69  ? 183 THR A CB  1 
ATOM   956  O OG1 . THR A 1 183 ? 170.149 154.358 133.965 1.00 89.69  ? 183 THR A OG1 1 
ATOM   957  C CG2 . THR A 1 183 ? 171.905 154.029 135.476 1.00 89.69  ? 183 THR A CG2 1 
ATOM   958  N N   . GLY A 1 184 ? 172.415 157.920 135.448 1.00 89.45  ? 184 GLY A N   1 
ATOM   959  C CA  . GLY A 1 184 ? 173.442 158.723 136.081 1.00 89.45  ? 184 GLY A CA  1 
ATOM   960  C C   . GLY A 1 184 ? 172.886 159.574 137.202 1.00 89.45  ? 184 GLY A C   1 
ATOM   961  O O   . GLY A 1 184 ? 173.621 160.012 138.087 1.00 89.45  ? 184 GLY A O   1 
ATOM   962  N N   . VAL A 1 185 ? 171.586 159.856 137.160 1.00 89.73  ? 185 VAL A N   1 
ATOM   963  C CA  . VAL A 1 185 ? 170.969 160.538 138.295 1.00 89.73  ? 185 VAL A CA  1 
ATOM   964  C C   . VAL A 1 185 ? 170.715 159.556 139.436 1.00 89.73  ? 185 VAL A C   1 
ATOM   965  O O   . VAL A 1 185 ? 171.014 159.837 140.601 1.00 89.73  ? 185 VAL A O   1 
ATOM   966  C CB  . VAL A 1 185 ? 169.681 161.254 137.860 1.00 89.73  ? 185 VAL A CB  1 
ATOM   967  C CG1 . VAL A 1 185 ? 168.886 161.682 139.072 1.00 89.73  ? 185 VAL A CG1 1 
ATOM   968  C CG2 . VAL A 1 185 ? 170.028 162.461 137.019 1.00 89.73  ? 185 VAL A CG2 1 
ATOM   969  N N   . SER A 1 186 ? 170.180 158.381 139.112 1.00 86.19  ? 186 SER A N   1 
ATOM   970  C CA  . SER A 1 186 ? 169.709 157.426 140.107 1.00 86.19  ? 186 SER A CA  1 
ATOM   971  C C   . SER A 1 186 ? 170.797 156.534 140.681 1.00 86.19  ? 186 SER A C   1 
ATOM   972  O O   . SER A 1 186 ? 170.546 155.873 141.691 1.00 86.19  ? 186 SER A O   1 
ATOM   973  C CB  . SER A 1 186 ? 168.631 156.535 139.504 1.00 86.19  ? 186 SER A CB  1 
ATOM   974  O OG  . SER A 1 186 ? 168.290 155.502 140.404 1.00 86.19  ? 186 SER A OG  1 
ATOM   975  N N   . GLY A 1 187 ? 171.970 156.462 140.070 1.00 89.43  ? 187 GLY A N   1 
ATOM   976  C CA  . GLY A 1 187 ? 173.025 155.638 140.598 1.00 89.43  ? 187 GLY A CA  1 
ATOM   977  C C   . GLY A 1 187 ? 173.721 156.307 141.758 1.00 89.43  ? 187 GLY A C   1 
ATOM   978  O O   . GLY A 1 187 ? 173.623 155.866 142.906 1.00 89.43  ? 187 GLY A O   1 
ATOM   979  N N   . PRO A 1 188 ? 174.410 157.416 141.483 1.00 90.18  ? 188 PRO A N   1 
ATOM   980  C CA  . PRO A 1 188 ? 175.112 158.118 142.563 1.00 90.18  ? 188 PRO A CA  1 
ATOM   981  C C   . PRO A 1 188 ? 174.207 158.504 143.707 1.00 90.18  ? 188 PRO A C   1 
ATOM   982  O O   . PRO A 1 188 ? 174.661 158.532 144.851 1.00 90.18  ? 188 PRO A O   1 
ATOM   983  C CB  . PRO A 1 188 ? 175.695 159.357 141.869 1.00 90.18  ? 188 PRO A CB  1 
ATOM   984  C CG  . PRO A 1 188 ? 175.381 159.224 140.434 1.00 90.18  ? 188 PRO A CG  1 
ATOM   985  C CD  . PRO A 1 188 ? 174.859 157.864 140.161 1.00 90.18  ? 188 PRO A CD  1 
ATOM   986  N N   . PHE A 1 189 ? 172.936 158.790 143.446 1.00 89.75  ? 189 PHE A N   1 
ATOM   987  C CA  . PHE A 1 189 ? 172.014 159.023 144.549 1.00 89.75  ? 189 PHE A CA  1 
ATOM   988  C C   . PHE A 1 189 ? 171.841 157.761 145.382 1.00 89.75  ? 189 PHE A C   1 
ATOM   989  O O   . PHE A 1 189 ? 171.753 157.826 146.614 1.00 89.75  ? 189 PHE A O   1 
ATOM   990  C CB  . PHE A 1 189 ? 170.675 159.508 144.012 1.00 89.75  ? 189 PHE A CB  1 
ATOM   991  C CG  . PHE A 1 189 ? 169.724 159.924 145.075 1.00 89.75  ? 189 PHE A CG  1 
ATOM   992  C CD1 . PHE A 1 189 ? 169.907 161.116 145.745 1.00 89.75  ? 189 PHE A CD1 1 
ATOM   993  C CD2 . PHE A 1 189 ? 168.639 159.143 145.396 1.00 89.75  ? 189 PHE A CD2 1 
ATOM   994  C CE1 . PHE A 1 189 ? 169.031 161.511 146.724 1.00 89.75  ? 189 PHE A CE1 1 
ATOM   995  C CE2 . PHE A 1 189 ? 167.761 159.538 146.371 1.00 89.75  ? 189 PHE A CE2 1 
ATOM   996  C CZ  . PHE A 1 189 ? 167.955 160.719 147.036 1.00 89.75  ? 189 PHE A CZ  1 
ATOM   997  N N   . GLY A 1 190 ? 171.809 156.601 144.729 1.00 90.39  ? 190 GLY A N   1 
ATOM   998  C CA  . GLY A 1 190 ? 171.751 155.352 145.468 1.00 90.39  ? 190 GLY A CA  1 
ATOM   999  C C   . GLY A 1 190 ? 172.990 155.119 146.308 1.00 90.39  ? 190 GLY A C   1 
ATOM   1000 O O   . GLY A 1 190 ? 172.900 154.725 147.472 1.00 90.39  ? 190 GLY A O   1 
ATOM   1001 N N   . ILE A 1 191 ? 174.169 155.357 145.730 1.00 90.91  ? 191 ILE A N   1 
ATOM   1002 C CA  . ILE A 1 191 ? 175.390 155.202 146.519 1.00 90.91  ? 191 ILE A CA  1 
ATOM   1003 C C   . ILE A 1 191 ? 175.442 156.232 147.638 1.00 90.91  ? 191 ILE A C   1 
ATOM   1004 O O   . ILE A 1 191 ? 175.994 155.961 148.707 1.00 90.91  ? 191 ILE A O   1 
ATOM   1005 C CB  . ILE A 1 191 ? 176.660 155.248 145.642 1.00 90.91  ? 191 ILE A CB  1 
ATOM   1006 C CG1 . ILE A 1 191 ? 176.732 154.058 144.687 1.00 90.91  ? 191 ILE A CG1 1 
ATOM   1007 C CG2 . ILE A 1 191 ? 177.906 155.244 146.489 1.00 90.91  ? 191 ILE A CG2 1 
ATOM   1008 C CD1 . ILE A 1 191 ? 176.108 154.272 143.362 1.00 90.91  ? 191 ILE A CD1 1 
ATOM   1009 N N   . TYR A 1 192 ? 174.864 157.412 147.437 1.00 94.37  ? 192 TYR A N   1 
ATOM   1010 C CA  . TYR A 1 192 ? 174.815 158.387 148.518 1.00 94.37  ? 192 TYR A CA  1 
ATOM   1011 C C   . TYR A 1 192 ? 173.958 157.865 149.660 1.00 94.37  ? 192 TYR A C   1 
ATOM   1012 O O   . TYR A 1 192 ? 174.392 157.831 150.816 1.00 94.37  ? 192 TYR A O   1 
ATOM   1013 C CB  . TYR A 1 192 ? 174.265 159.714 147.997 1.00 94.37  ? 192 TYR A CB  1 
ATOM   1014 C CG  . TYR A 1 192 ? 174.115 160.811 149.029 1.00 94.37  ? 192 TYR A CG  1 
ATOM   1015 C CD1 . TYR A 1 192 ? 174.790 160.764 150.240 1.00 94.37  ? 192 TYR A CD1 1 
ATOM   1016 C CD2 . TYR A 1 192 ? 173.293 161.898 148.786 1.00 94.37  ? 192 TYR A CD2 1 
ATOM   1017 C CE1 . TYR A 1 192 ? 174.650 161.764 151.174 1.00 94.37  ? 192 TYR A CE1 1 
ATOM   1018 C CE2 . TYR A 1 192 ? 173.146 162.904 149.715 1.00 94.37  ? 192 TYR A CE2 1 
ATOM   1019 C CZ  . TYR A 1 192 ? 173.828 162.831 150.907 1.00 94.37  ? 192 TYR A CZ  1 
ATOM   1020 O OH  . TYR A 1 192 ? 173.690 163.830 151.840 1.00 94.37  ? 192 TYR A OH  1 
ATOM   1021 N N   . CYS A 1 193 ? 172.747 157.420 149.348 1.00 95.95  ? 193 CYS A N   1 
ATOM   1022 C CA  . CYS A 1 193 ? 171.836 156.902 150.357 1.00 95.95  ? 193 CYS A CA  1 
ATOM   1023 C C   . CYS A 1 193 ? 172.365 155.647 151.032 1.00 95.95  ? 193 CYS A C   1 
ATOM   1024 O O   . CYS A 1 193 ? 171.980 155.361 152.167 1.00 95.95  ? 193 CYS A O   1 
ATOM   1025 C CB  . CYS A 1 193 ? 170.472 156.621 149.735 1.00 95.95  ? 193 CYS A CB  1 
ATOM   1026 S SG  . CYS A 1 193 ? 169.256 156.044 150.914 1.00 95.95  ? 193 CYS A SG  1 
ATOM   1027 N N   . MET A 1 194 ? 173.228 154.894 150.359 1.00 92.94  ? 194 MET A N   1 
ATOM   1028 C CA  . MET A 1 194 ? 173.911 153.760 150.962 1.00 92.94  ? 194 MET A CA  1 
ATOM   1029 C C   . MET A 1 194 ? 175.153 154.168 151.735 1.00 92.94  ? 194 MET A C   1 
ATOM   1030 O O   . MET A 1 194 ? 175.616 153.406 152.587 1.00 92.94  ? 194 MET A O   1 
ATOM   1031 C CB  . MET A 1 194 ? 174.300 152.753 149.880 1.00 92.94  ? 194 MET A CB  1 
ATOM   1032 C CG  . MET A 1 194 ? 174.837 151.442 150.391 1.00 92.94  ? 194 MET A CG  1 
ATOM   1033 S SD  . MET A 1 194 ? 175.907 150.666 149.176 1.00 92.94  ? 194 MET A SD  1 
ATOM   1034 C CE  . MET A 1 194 ? 175.912 148.987 149.762 1.00 92.94  ? 194 MET A CE  1 
ATOM   1035 N N   . TYR A 1 195 ? 175.687 155.356 151.475 1.00 99.46  ? 195 TYR A N   1 
ATOM   1036 C CA  . TYR A 1 195 ? 176.922 155.819 152.084 1.00 99.46  ? 195 TYR A CA  1 
ATOM   1037 C C   . TYR A 1 195 ? 176.741 156.154 153.556 1.00 99.46  ? 195 TYR A C   1 
ATOM   1038 O O   . TYR A 1 195 ? 177.431 155.592 154.410 1.00 99.46  ? 195 TYR A O   1 
ATOM   1039 C CB  . TYR A 1 195 ? 177.439 157.038 151.321 1.00 99.46  ? 195 TYR A CB  1 
ATOM   1040 C CG  . TYR A 1 195 ? 178.677 157.670 151.902 1.00 99.46  ? 195 TYR A CG  1 
ATOM   1041 C CD1 . TYR A 1 195 ? 179.916 157.082 151.744 1.00 99.46  ? 195 TYR A CD1 1 
ATOM   1042 C CD2 . TYR A 1 195 ? 178.604 158.867 152.593 1.00 99.46  ? 195 TYR A CD2 1 
ATOM   1043 C CE1 . TYR A 1 195 ? 181.046 157.663 152.268 1.00 99.46  ? 195 TYR A CE1 1 
ATOM   1044 C CE2 . TYR A 1 195 ? 179.725 159.452 153.119 1.00 99.46  ? 195 TYR A CE2 1 
ATOM   1045 C CZ  . TYR A 1 195 ? 180.944 158.848 152.954 1.00 99.46  ? 195 TYR A CZ  1 
ATOM   1046 O OH  . TYR A 1 195 ? 182.071 159.432 153.479 1.00 99.46  ? 195 TYR A OH  1 
ATOM   1047 N N   . HIS A 1 196 ? 175.820 157.061 153.872 1.00 98.71  ? 196 HIS A N   1 
ATOM   1048 C CA  . HIS A 1 196 ? 175.625 157.442 155.263 1.00 98.71  ? 196 HIS A CA  1 
ATOM   1049 C C   . HIS A 1 196 ? 174.636 156.502 155.935 1.00 98.71  ? 196 HIS A C   1 
ATOM   1050 O O   . HIS A 1 196 ? 173.653 156.936 156.543 1.00 98.71  ? 196 HIS A O   1 
ATOM   1051 C CB  . HIS A 1 196 ? 175.177 158.901 155.367 1.00 98.71  ? 196 HIS A CB  1 
ATOM   1052 C CG  . HIS A 1 196 ? 173.830 159.169 154.781 1.00 98.71  ? 196 HIS A CG  1 
ATOM   1053 N ND1 . HIS A 1 196 ? 172.662 158.935 155.471 1.00 98.71  ? 196 HIS A ND1 1 
ATOM   1054 C CD2 . HIS A 1 196 ? 173.463 159.669 153.579 1.00 98.71  ? 196 HIS A CD2 1 
ATOM   1055 C CE1 . HIS A 1 196 ? 171.632 159.271 154.716 1.00 98.71  ? 196 HIS A CE1 1 
ATOM   1056 N NE2 . HIS A 1 196 ? 172.091 159.720 153.563 1.00 98.71  ? 196 HIS A NE2 1 
ATOM   1057 N N   . SER A 1 197 ? 174.899 155.205 155.836 1.00 95.92  ? 197 SER A N   1 
ATOM   1058 C CA  . SER A 1 197 ? 174.110 154.203 156.529 1.00 95.92  ? 197 SER A CA  1 
ATOM   1059 C C   . SER A 1 197 ? 174.998 152.993 156.755 1.00 95.92  ? 197 SER A C   1 
ATOM   1060 O O   . SER A 1 197 ? 176.049 152.857 156.124 1.00 95.92  ? 197 SER A O   1 
ATOM   1061 C CB  . SER A 1 197 ? 172.859 153.814 155.743 1.00 95.92  ? 197 SER A CB  1 
ATOM   1062 O OG  . SER A 1 197 ? 173.210 153.092 154.584 1.00 95.92  ? 197 SER A OG  1 
ATOM   1063 N N   . ASP A 1 198 ? 174.563 152.114 157.648 1.00 95.13  ? 198 ASP A N   1 
ATOM   1064 C CA  . ASP A 1 198 ? 175.382 150.982 158.058 1.00 95.13  ? 198 ASP A CA  1 
ATOM   1065 C C   . ASP A 1 198 ? 175.484 149.905 156.982 1.00 95.13  ? 198 ASP A C   1 
ATOM   1066 O O   . ASP A 1 198 ? 175.939 148.792 157.258 1.00 95.13  ? 198 ASP A O   1 
ATOM   1067 C CB  . ASP A 1 198 ? 174.843 150.402 159.367 1.00 95.13  ? 198 ASP A CB  1 
ATOM   1068 C CG  . ASP A 1 198 ? 173.434 149.863 159.236 1.00 95.13  ? 198 ASP A CG  1 
ATOM   1069 O OD1 . ASP A 1 198 ? 172.845 149.967 158.143 1.00 95.13  ? 198 ASP A OD1 1 
ATOM   1070 O OD2 . ASP A 1 198 ? 172.905 149.342 160.239 1.00 95.13  ? 198 ASP A OD2 1 
ATOM   1071 N N   . LEU A 1 199 ? 175.072 150.225 155.760 1.00 91.62  ? 199 LEU A N   1 
ATOM   1072 C CA  . LEU A 1 199 ? 175.097 149.286 154.649 1.00 91.62  ? 199 LEU A CA  1 
ATOM   1073 C C   . LEU A 1 199 ? 176.391 149.316 153.850 1.00 91.62  ? 199 LEU A C   1 
ATOM   1074 O O   . LEU A 1 199 ? 176.499 148.584 152.863 1.00 91.62  ? 199 LEU A O   1 
ATOM   1075 C CB  . LEU A 1 199 ? 173.932 149.565 153.702 1.00 91.62  ? 199 LEU A CB  1 
ATOM   1076 C CG  . LEU A 1 199 ? 172.555 149.031 154.065 1.00 91.62  ? 199 LEU A CG  1 
ATOM   1077 C CD1 . LEU A 1 199 ? 171.531 149.602 153.121 1.00 91.62  ? 199 LEU A CD1 1 
ATOM   1078 C CD2 . LEU A 1 199 ? 172.565 147.531 153.970 1.00 91.62  ? 199 LEU A CD2 1 
ATOM   1079 N N   . TRP A 1 200 ? 177.372 150.119 154.253 1.00 97.27  ? 200 TRP A N   1 
ATOM   1080 C CA  . TRP A 1 200 ? 178.478 150.475 153.369 1.00 97.27  ? 200 TRP A CA  1 
ATOM   1081 C C   . TRP A 1 200 ? 179.222 149.246 152.857 1.00 97.27  ? 200 TRP A C   1 
ATOM   1082 O O   . TRP A 1 200 ? 179.566 148.344 153.625 1.00 97.27  ? 200 TRP A O   1 
ATOM   1083 C CB  . TRP A 1 200 ? 179.441 151.404 154.103 1.00 97.27  ? 200 TRP A CB  1 
ATOM   1084 C CG  . TRP A 1 200 ? 180.442 152.066 153.215 1.00 97.27  ? 200 TRP A CG  1 
ATOM   1085 C CD1 . TRP A 1 200 ? 181.779 152.164 153.431 1.00 97.27  ? 200 TRP A CD1 1 
ATOM   1086 C CD2 . TRP A 1 200 ? 180.183 152.757 151.988 1.00 97.27  ? 200 TRP A CD2 1 
ATOM   1087 N NE1 . TRP A 1 200 ? 182.375 152.856 152.409 1.00 97.27  ? 200 TRP A NE1 1 
ATOM   1088 C CE2 . TRP A 1 200 ? 181.414 153.233 151.512 1.00 97.27  ? 200 TRP A CE2 1 
ATOM   1089 C CE3 . TRP A 1 200 ? 179.032 153.014 151.244 1.00 97.27  ? 200 TRP A CE3 1 
ATOM   1090 C CZ2 . TRP A 1 200 ? 181.526 153.946 150.330 1.00 97.27  ? 200 TRP A CZ2 1 
ATOM   1091 C CZ3 . TRP A 1 200 ? 179.147 153.719 150.072 1.00 97.27  ? 200 TRP A CZ3 1 
ATOM   1092 C CH2 . TRP A 1 200 ? 180.383 154.177 149.626 1.00 97.27  ? 200 TRP A CH2 1 
ATOM   1093 N N   . PHE A 1 201 ? 179.534 149.297 151.626 1.00 100.83 ? 201 PHE A N   1 
ATOM   1094 C CA  . PHE A 1 201 ? 180.089 148.197 150.990 1.00 100.83 ? 201 PHE A CA  1 
ATOM   1095 C C   . PHE A 1 201 ? 179.575 146.859 151.114 1.00 100.83 ? 201 PHE A C   1 
ATOM   1096 O O   . PHE A 1 201 ? 180.307 145.951 151.178 1.00 100.83 ? 201 PHE A O   1 
ATOM   1097 C CB  . PHE A 1 201 ? 181.475 148.300 150.637 1.00 100.83 ? 201 PHE A CB  1 
ATOM   1098 C CG  . PHE A 1 201 ? 181.558 148.642 149.278 1.00 100.83 ? 201 PHE A CG  1 
ATOM   1099 C CD1 . PHE A 1 201 ? 181.771 147.705 148.366 1.00 100.83 ? 201 PHE A CD1 1 
ATOM   1100 C CD2 . PHE A 1 201 ? 181.140 149.855 148.910 1.00 100.83 ? 201 PHE A CD2 1 
ATOM   1101 C CE1 . PHE A 1 201 ? 181.731 148.010 147.069 1.00 100.83 ? 201 PHE A CE1 1 
ATOM   1102 C CE2 . PHE A 1 201 ? 181.090 150.175 147.624 1.00 100.83 ? 201 PHE A CE2 1 
ATOM   1103 C CZ  . PHE A 1 201 ? 181.388 149.244 146.697 1.00 100.83 ? 201 PHE A CZ  1 
ATOM   1104 N N   . PHE A 1 202 ? 178.283 146.787 150.934 1.00 94.16  ? 202 PHE A N   1 
ATOM   1105 C CA  . PHE A 1 202 ? 177.522 145.602 150.968 1.00 94.16  ? 202 PHE A CA  1 
ATOM   1106 C C   . PHE A 1 202 ? 177.885 144.790 152.106 1.00 94.16  ? 202 PHE A C   1 
ATOM   1107 O O   . PHE A 1 202 ? 178.417 143.742 151.990 1.00 94.16  ? 202 PHE A O   1 
ATOM   1108 C CB  . PHE A 1 202 ? 177.670 144.852 149.723 1.00 94.16  ? 202 PHE A CB  1 
ATOM   1109 C CG  . PHE A 1 202 ? 177.353 145.641 148.538 1.00 94.16  ? 202 PHE A CG  1 
ATOM   1110 C CD1 . PHE A 1 202 ? 176.179 145.514 147.942 1.00 94.16  ? 202 PHE A CD1 1 
ATOM   1111 C CD2 . PHE A 1 202 ? 178.240 146.473 148.031 1.00 94.16  ? 202 PHE A CD2 1 
ATOM   1112 C CE1 . PHE A 1 202 ? 175.887 146.213 146.845 1.00 94.16  ? 202 PHE A CE1 1 
ATOM   1113 C CE2 . PHE A 1 202 ? 177.985 147.155 146.938 1.00 94.16  ? 202 PHE A CE2 1 
ATOM   1114 C CZ  . PHE A 1 202 ? 176.799 147.037 146.349 1.00 94.16  ? 202 PHE A CZ  1 
ATOM   1115 N N   . ASN A 1 203 ? 177.475 145.264 153.240 1.00 92.31  ? 203 ASN A N   1 
ATOM   1116 C CA  . ASN A 1 203 ? 177.796 144.595 154.410 1.00 92.31  ? 203 ASN A CA  1 
ATOM   1117 C C   . ASN A 1 203 ? 176.503 144.139 154.789 1.00 92.31  ? 203 ASN A C   1 
ATOM   1118 O O   . ASN A 1 203 ? 175.799 144.799 155.419 1.00 92.31  ? 203 ASN A O   1 
ATOM   1119 C CB  . ASN A 1 203 ? 178.285 145.612 155.362 1.00 92.31  ? 203 ASN A CB  1 
ATOM   1120 C CG  . ASN A 1 203 ? 178.094 145.186 156.724 1.00 92.31  ? 203 ASN A CG  1 
ATOM   1121 O OD1 . ASN A 1 203 ? 178.081 144.016 156.970 1.00 92.31  ? 203 ASN A OD1 1 
ATOM   1122 N ND2 . ASN A 1 203 ? 177.850 146.113 157.610 1.00 92.31  ? 203 ASN A ND2 1 
ATOM   1123 N N   . THR A 1 204 ? 176.184 142.953 154.276 1.00 87.77  ? 204 THR A N   1 
ATOM   1124 C CA  . THR A 1 204 ? 174.916 142.291 154.508 1.00 87.77  ? 204 THR A CA  1 
ATOM   1125 C C   . THR A 1 204 ? 174.632 142.238 155.990 1.00 87.77  ? 204 THR A C   1 
ATOM   1126 O O   . THR A 1 204 ? 173.534 142.584 156.427 1.00 87.77  ? 204 THR A O   1 
ATOM   1127 C CB  . THR A 1 204 ? 174.914 140.859 153.943 1.00 87.77  ? 204 THR A CB  1 
ATOM   1128 O OG1 . THR A 1 204 ? 176.037 140.136 154.462 1.00 87.77  ? 204 THR A OG1 1 
ATOM   1129 C CG2 . THR A 1 204 ? 174.992 140.886 152.424 1.00 87.77  ? 204 THR A CG2 1 
ATOM   1130 N N   . LYS A 1 205 ? 175.612 141.806 156.777 1.00 89.60  ? 205 LYS A N   1 
ATOM   1131 C CA  . LYS A 1 205 ? 175.355 141.761 158.210 1.00 89.60  ? 205 LYS A CA  1 
ATOM   1132 C C   . LYS A 1 205 ? 174.445 142.913 158.663 1.00 89.60  ? 205 LYS A C   1 
ATOM   1133 O O   . LYS A 1 205 ? 173.966 142.914 159.797 1.00 89.60  ? 205 LYS A O   1 
ATOM   1134 C CB  . LYS A 1 205 ? 176.670 141.792 158.991 1.00 89.60  ? 205 LYS A CB  1 
ATOM   1135 C CG  . LYS A 1 205 ? 176.502 141.649 160.495 1.00 89.60  ? 205 LYS A CG  1 
ATOM   1136 C CD  . LYS A 1 205 ? 176.301 143.000 161.160 1.00 89.60  ? 205 LYS A CD  1 
ATOM   1137 C CE  . LYS A 1 205 ? 175.749 142.846 162.568 1.00 89.60  ? 205 LYS A CE  1 
ATOM   1138 N NZ  . LYS A 1 205 ? 175.384 144.157 163.169 1.00 89.60  ? 205 LYS A NZ  1 
ATOM   1139 N N   . ALA A 1 206 ? 174.206 143.888 157.784 1.00 86.67  ? 206 ALA A N   1 
ATOM   1140 C CA  . ALA A 1 206 ? 173.358 145.020 158.125 1.00 86.67  ? 206 ALA A CA  1 
ATOM   1141 C C   . ALA A 1 206 ? 171.980 144.971 157.491 1.00 86.67  ? 206 ALA A C   1 
ATOM   1142 O O   . ALA A 1 206 ? 171.123 145.774 157.864 1.00 86.67  ? 206 ALA A O   1 
ATOM   1143 C CB  . ALA A 1 206 ? 174.032 146.332 157.721 1.00 86.67  ? 206 ALA A CB  1 
ATOM   1144 N N   . MET A 1 207 ? 171.742 144.064 156.550 1.00 82.76  ? 207 MET A N   1 
ATOM   1145 C CA  . MET A 1 207 ? 170.437 143.985 155.911 1.00 82.76  ? 207 MET A CA  1 
ATOM   1146 C C   . MET A 1 207 ? 169.428 143.199 156.731 1.00 82.76  ? 207 MET A C   1 
ATOM   1147 O O   . MET A 1 207 ? 168.245 143.183 156.380 1.00 82.76  ? 207 MET A O   1 
ATOM   1148 C CB  . MET A 1 207 ? 170.572 143.364 154.521 1.00 82.76  ? 207 MET A CB  1 
ATOM   1149 C CG  . MET A 1 207 ? 171.574 144.073 153.631 1.00 82.76  ? 207 MET A CG  1 
ATOM   1150 S SD  . MET A 1 207 ? 171.553 143.524 151.918 1.00 82.76  ? 207 MET A SD  1 
ATOM   1151 C CE  . MET A 1 207 ? 171.596 141.751 152.119 1.00 82.76  ? 207 MET A CE  1 
ATOM   1152 N N   . TYR A 1 208 ? 169.864 142.557 157.810 1.00 80.82  ? 208 TYR A N   1 
ATOM   1153 C CA  . TYR A 1 208 ? 168.999 141.755 158.651 1.00 80.82  ? 208 TYR A CA  1 
ATOM   1154 C C   . TYR A 1 208 ? 169.118 142.081 160.127 1.00 80.82  ? 208 TYR A C   1 
ATOM   1155 O O   . TYR A 1 208 ? 168.295 141.604 160.912 1.00 80.82  ? 208 TYR A O   1 
ATOM   1156 C CB  . TYR A 1 208 ? 169.310 140.265 158.465 1.00 80.82  ? 208 TYR A CB  1 
ATOM   1157 C CG  . TYR A 1 208 ? 169.516 139.850 157.039 1.00 80.82  ? 208 TYR A CG  1 
ATOM   1158 C CD1 . TYR A 1 208 ? 168.471 139.858 156.140 1.00 80.82  ? 208 TYR A CD1 1 
ATOM   1159 C CD2 . TYR A 1 208 ? 170.759 139.466 156.587 1.00 80.82  ? 208 TYR A CD2 1 
ATOM   1160 C CE1 . TYR A 1 208 ? 168.654 139.477 154.836 1.00 80.82  ? 208 TYR A CE1 1 
ATOM   1161 C CE2 . TYR A 1 208 ? 170.952 139.088 155.287 1.00 80.82  ? 208 TYR A CE2 1 
ATOM   1162 C CZ  . TYR A 1 208 ? 169.897 139.097 154.416 1.00 80.82  ? 208 TYR A CZ  1 
ATOM   1163 O OH  . TYR A 1 208 ? 170.083 138.722 153.111 1.00 80.82  ? 208 TYR A OH  1 
ATOM   1164 N N   . ARG A 1 209 ? 170.109 142.868 160.530 1.00 88.21  ? 209 ARG A N   1 
ATOM   1165 C CA  . ARG A 1 209 ? 170.379 143.100 161.941 1.00 88.21  ? 209 ARG A CA  1 
ATOM   1166 C C   . ARG A 1 209 ? 169.205 143.787 162.622 1.00 88.21  ? 209 ARG A C   1 
ATOM   1167 O O   . ARG A 1 209 ? 169.033 143.679 163.838 1.00 88.21  ? 209 ARG A O   1 
ATOM   1168 C CB  . ARG A 1 209 ? 171.661 143.915 162.097 1.00 88.21  ? 209 ARG A CB  1 
ATOM   1169 C CG  . ARG A 1 209 ? 172.117 144.085 163.522 1.00 88.21  ? 209 ARG A CG  1 
ATOM   1170 C CD  . ARG A 1 209 ? 171.943 145.517 163.967 1.00 88.21  ? 209 ARG A CD  1 
ATOM   1171 N NE  . ARG A 1 209 ? 172.754 146.413 163.153 1.00 88.21  ? 209 ARG A NE  1 
ATOM   1172 C CZ  . ARG A 1 209 ? 172.640 147.735 163.157 1.00 88.21  ? 209 ARG A CZ  1 
ATOM   1173 N NH1 . ARG A 1 209 ? 171.747 148.322 163.938 1.00 88.21  ? 209 ARG A NH1 1 
ATOM   1174 N NH2 . ARG A 1 209 ? 173.422 148.470 162.381 1.00 88.21  ? 209 ARG A NH2 1 
ATOM   1175 N N   . THR A 1 210 ? 168.384 144.487 161.846 1.00 81.45  ? 210 THR A N   1 
ATOM   1176 C CA  . THR A 1 210 ? 167.126 145.021 162.360 1.00 81.45  ? 210 THR A CA  1 
ATOM   1177 C C   . THR A 1 210 ? 166.073 144.822 161.271 1.00 81.45  ? 210 THR A C   1 
ATOM   1178 O O   . THR A 1 210 ? 165.901 145.678 160.401 1.00 81.45  ? 210 THR A O   1 
ATOM   1179 C CB  . THR A 1 210 ? 167.278 146.479 162.790 1.00 81.45  ? 210 THR A CB  1 
ATOM   1180 O OG1 . THR A 1 210 ? 166.057 146.953 163.369 1.00 81.45  ? 210 THR A OG1 1 
ATOM   1181 C CG2 . THR A 1 210 ? 167.774 147.398 161.670 1.00 81.45  ? 210 THR A CG2 1 
ATOM   1182 N N   . TYR A 1 211 ? 165.390 143.687 161.317 1.00 71.96  ? 211 TYR A N   1 
ATOM   1183 C CA  . TYR A 1 211 ? 164.636 143.340 160.125 1.00 71.96  ? 211 TYR A CA  1 
ATOM   1184 C C   . TYR A 1 211 ? 163.353 144.145 159.960 1.00 71.96  ? 211 TYR A C   1 
ATOM   1185 O O   . TYR A 1 211 ? 163.194 144.786 158.916 1.00 71.96  ? 211 TYR A O   1 
ATOM   1186 C CB  . TYR A 1 211 ? 164.281 141.857 160.067 1.00 71.96  ? 211 TYR A CB  1 
ATOM   1187 C CG  . TYR A 1 211 ? 163.128 141.653 159.125 1.00 71.96  ? 211 TYR A CG  1 
ATOM   1188 C CD1 . TYR A 1 211 ? 163.247 141.958 157.781 1.00 71.96  ? 211 TYR A CD1 1 
ATOM   1189 C CD2 . TYR A 1 211 ? 161.905 141.221 159.584 1.00 71.96  ? 211 TYR A CD2 1 
ATOM   1190 C CE1 . TYR A 1 211 ? 162.191 141.813 156.930 1.00 71.96  ? 211 TYR A CE1 1 
ATOM   1191 C CE2 . TYR A 1 211 ? 160.846 141.068 158.732 1.00 71.96  ? 211 TYR A CE2 1 
ATOM   1192 C CZ  . TYR A 1 211 ? 160.995 141.364 157.411 1.00 71.96  ? 211 TYR A CZ  1 
ATOM   1193 O OH  . TYR A 1 211 ? 159.931 141.208 156.566 1.00 71.96  ? 211 TYR A OH  1 
ATOM   1194 N N   . PRO A 1 212 ? 162.412 144.135 160.915 1.00 74.56  ? 212 PRO A N   1 
ATOM   1195 C CA  . PRO A 1 212 ? 161.061 144.619 160.585 1.00 74.56  ? 212 PRO A CA  1 
ATOM   1196 C C   . PRO A 1 212 ? 161.037 145.983 159.923 1.00 74.56  ? 212 PRO A C   1 
ATOM   1197 O O   . PRO A 1 212 ? 160.160 146.212 159.091 1.00 74.56  ? 212 PRO A O   1 
ATOM   1198 C CB  . PRO A 1 212 ? 160.341 144.632 161.935 1.00 74.56  ? 212 PRO A CB  1 
ATOM   1199 C CG  . PRO A 1 212 ? 161.077 143.707 162.782 1.00 74.56  ? 212 PRO A CG  1 
ATOM   1200 C CD  . PRO A 1 212 ? 162.478 143.594 162.284 1.00 74.56  ? 212 PRO A CD  1 
ATOM   1201 N N   . ASP A 1 213 ? 161.953 146.886 160.263 1.00 73.44  ? 213 ASP A N   1 
ATOM   1202 C CA  . ASP A 1 213 ? 162.205 148.120 159.510 1.00 73.44  ? 213 ASP A CA  1 
ATOM   1203 C C   . ASP A 1 213 ? 160.916 148.773 159.010 1.00 73.44  ? 213 ASP A C   1 
ATOM   1204 O O   . ASP A 1 213 ? 160.708 148.968 157.818 1.00 73.44  ? 213 ASP A O   1 
ATOM   1205 C CB  . ASP A 1 213 ? 163.134 147.850 158.327 1.00 73.44  ? 213 ASP A CB  1 
ATOM   1206 C CG  . ASP A 1 213 ? 164.581 147.995 158.687 1.00 73.44  ? 213 ASP A CG  1 
ATOM   1207 O OD1 . ASP A 1 213 ? 164.873 148.624 159.724 1.00 73.44  ? 213 ASP A OD1 1 
ATOM   1208 O OD2 . ASP A 1 213 ? 165.425 147.478 157.931 1.00 73.44  ? 213 ASP A OD2 1 
ATOM   1209 N N   . PHE A 1 214 ? 160.042 149.094 159.955 1.00 67.02  ? 214 PHE A N   1 
ATOM   1210 C CA  . PHE A 1 214 ? 158.785 149.713 159.577 1.00 67.02  ? 214 PHE A CA  1 
ATOM   1211 C C   . PHE A 1 214 ? 158.961 151.129 159.060 1.00 67.02  ? 214 PHE A C   1 
ATOM   1212 O O   . PHE A 1 214 ? 158.073 151.633 158.370 1.00 67.02  ? 214 PHE A O   1 
ATOM   1213 C CB  . PHE A 1 214 ? 157.825 149.727 160.759 1.00 67.02  ? 214 PHE A CB  1 
ATOM   1214 C CG  . PHE A 1 214 ? 157.408 148.372 161.211 1.00 67.02  ? 214 PHE A CG  1 
ATOM   1215 C CD1 . PHE A 1 214 ? 156.502 147.639 160.486 1.00 67.02  ? 214 PHE A CD1 1 
ATOM   1216 C CD2 . PHE A 1 214 ? 157.923 147.830 162.363 1.00 67.02  ? 214 PHE A CD2 1 
ATOM   1217 C CE1 . PHE A 1 214 ? 156.116 146.401 160.901 1.00 67.02  ? 214 PHE A CE1 1 
ATOM   1218 C CE2 . PHE A 1 214 ? 157.540 146.589 162.779 1.00 67.02  ? 214 PHE A CE2 1 
ATOM   1219 C CZ  . PHE A 1 214 ? 156.636 145.876 162.047 1.00 67.02  ? 214 PHE A CZ  1 
ATOM   1220 N N   . THR A 1 215 ? 160.077 151.779 159.369 1.00 69.36  ? 215 THR A N   1 
ATOM   1221 C CA  . THR A 1 215 ? 160.281 153.180 159.039 1.00 69.36  ? 215 THR A CA  1 
ATOM   1222 C C   . THR A 1 215 ? 161.577 153.343 158.265 1.00 69.36  ? 215 THR A C   1 
ATOM   1223 O O   . THR A 1 215 ? 162.584 152.715 158.597 1.00 69.36  ? 215 THR A O   1 
ATOM   1224 C CB  . THR A 1 215 ? 160.321 154.040 160.297 1.00 69.36  ? 215 THR A CB  1 
ATOM   1225 O OG1 . THR A 1 215 ? 161.339 153.548 161.174 1.00 69.36  ? 215 THR A OG1 1 
ATOM   1226 C CG2 . THR A 1 215 ? 158.994 153.987 161.005 1.00 69.36  ? 215 THR A CG2 1 
ATOM   1227 N N   . ASN A 1 216 ? 161.548 154.191 157.246 1.00 66.53  ? 216 ASN A N   1 
ATOM   1228 C CA  . ASN A 1 216 ? 162.718 154.492 156.437 1.00 66.53  ? 216 ASN A CA  1 
ATOM   1229 C C   . ASN A 1 216 ? 163.136 155.939 156.641 1.00 66.53  ? 216 ASN A C   1 
ATOM   1230 O O   . ASN A 1 216 ? 162.301 156.777 156.996 1.00 66.53  ? 216 ASN A O   1 
ATOM   1231 C CB  . ASN A 1 216 ? 162.419 154.238 154.966 1.00 66.53  ? 216 ASN A CB  1 
ATOM   1232 C CG  . ASN A 1 216 ? 161.600 153.003 154.756 1.00 66.53  ? 216 ASN A CG  1 
ATOM   1233 O OD1 . ASN A 1 216 ? 162.056 151.899 155.023 1.00 66.53  ? 216 ASN A OD1 1 
ATOM   1234 N ND2 . ASN A 1 216 ? 160.376 153.177 154.286 1.00 66.53  ? 216 ASN A ND2 1 
ATOM   1235 N N   . PRO A 1 217 ? 164.400 156.277 156.430 1.00 65.76  ? 217 PRO A N   1 
ATOM   1236 C CA  . PRO A 1 217 ? 164.793 157.688 156.462 1.00 65.76  ? 217 PRO A CA  1 
ATOM   1237 C C   . PRO A 1 217 ? 164.136 158.472 155.343 1.00 65.76  ? 217 PRO A C   1 
ATOM   1238 O O   . PRO A 1 217 ? 163.419 157.898 154.523 1.00 65.76  ? 217 PRO A O   1 
ATOM   1239 C CB  . PRO A 1 217 ? 166.311 157.629 156.287 1.00 65.76  ? 217 PRO A CB  1 
ATOM   1240 C CG  . PRO A 1 217 ? 166.687 156.288 156.756 1.00 65.76  ? 217 PRO A CG  1 
ATOM   1241 C CD  . PRO A 1 217 ? 165.566 155.388 156.372 1.00 65.76  ? 217 PRO A CD  1 
ATOM   1242 N N   . PHE A 1 218 ? 164.368 159.779 155.285 1.00 68.50  ? 218 PHE A N   1 
ATOM   1243 C CA  . PHE A 1 218 ? 163.749 160.585 154.244 1.00 68.50  ? 218 PHE A CA  1 
ATOM   1244 C C   . PHE A 1 218 ? 164.311 160.211 152.884 1.00 68.50  ? 218 PHE A C   1 
ATOM   1245 O O   . PHE A 1 218 ? 163.563 159.801 151.995 1.00 68.50  ? 218 PHE A O   1 
ATOM   1246 C CB  . PHE A 1 218 ? 163.967 162.070 154.502 1.00 68.50  ? 218 PHE A CB  1 
ATOM   1247 C CG  . PHE A 1 218 ? 163.445 162.958 153.415 1.00 68.50  ? 218 PHE A CG  1 
ATOM   1248 C CD1 . PHE A 1 218 ? 162.107 163.289 153.361 1.00 68.50  ? 218 PHE A CD1 1 
ATOM   1249 C CD2 . PHE A 1 218 ? 164.287 163.463 152.448 1.00 68.50  ? 218 PHE A CD2 1 
ATOM   1250 C CE1 . PHE A 1 218 ? 161.624 164.108 152.374 1.00 68.50  ? 218 PHE A CE1 1 
ATOM   1251 C CE2 . PHE A 1 218 ? 163.804 164.277 151.457 1.00 68.50  ? 218 PHE A CE2 1 
ATOM   1252 C CZ  . PHE A 1 218 ? 162.471 164.598 151.422 1.00 68.50  ? 218 PHE A CZ  1 
ATOM   1253 N N   . LEU A 1 219 ? 165.629 160.342 152.718 1.00 73.72  ? 219 LEU A N   1 
ATOM   1254 C CA  . LEU A 1 219 ? 166.245 160.062 151.427 1.00 73.72  ? 219 LEU A CA  1 
ATOM   1255 C C   . LEU A 1 219 ? 165.942 158.652 150.968 1.00 73.72  ? 219 LEU A C   1 
ATOM   1256 O O   . LEU A 1 219 ? 165.724 158.405 149.781 1.00 73.72  ? 219 LEU A O   1 
ATOM   1257 C CB  . LEU A 1 219 ? 167.755 160.269 151.490 1.00 73.72  ? 219 LEU A CB  1 
ATOM   1258 C CG  . LEU A 1 219 ? 168.249 161.709 151.409 1.00 73.72  ? 219 LEU A CG  1 
ATOM   1259 C CD1 . LEU A 1 219 ? 169.760 161.732 151.274 1.00 73.72  ? 219 LEU A CD1 1 
ATOM   1260 C CD2 . LEU A 1 219 ? 167.593 162.431 150.252 1.00 73.72  ? 219 LEU A CD2 1 
ATOM   1261 N N   . PHE A 1 220 ? 165.983 157.716 151.911 1.00 67.20  ? 220 PHE A N   1 
ATOM   1262 C CA  . PHE A 1 220 ? 165.733 156.311 151.615 1.00 67.20  ? 220 PHE A CA  1 
ATOM   1263 C C   . PHE A 1 220 ? 164.358 156.112 150.995 1.00 67.20  ? 220 PHE A C   1 
ATOM   1264 O O   . PHE A 1 220 ? 164.228 155.522 149.923 1.00 67.20  ? 220 PHE A O   1 
ATOM   1265 C CB  . PHE A 1 220 ? 165.865 155.465 152.884 1.00 67.20  ? 220 PHE A CB  1 
ATOM   1266 C CG  . PHE A 1 220 ? 166.414 154.089 152.641 1.00 67.20  ? 220 PHE A CG  1 
ATOM   1267 C CD1 . PHE A 1 220 ? 167.573 153.670 153.273 1.00 67.20  ? 220 PHE A CD1 1 
ATOM   1268 C CD2 . PHE A 1 220 ? 165.771 153.213 151.782 1.00 67.20  ? 220 PHE A CD2 1 
ATOM   1269 C CE1 . PHE A 1 220 ? 168.082 152.404 153.052 1.00 67.20  ? 220 PHE A CE1 1 
ATOM   1270 C CE2 . PHE A 1 220 ? 166.274 151.946 151.557 1.00 67.20  ? 220 PHE A CE2 1 
ATOM   1271 C CZ  . PHE A 1 220 ? 167.432 151.541 152.193 1.00 67.20  ? 220 PHE A CZ  1 
ATOM   1272 N N   . LYS A 1 221 ? 163.334 156.609 151.677 1.00 62.19  ? 221 LYS A N   1 
ATOM   1273 C CA  . LYS A 1 221 ? 161.964 156.484 151.190 1.00 62.19  ? 221 LYS A CA  1 
ATOM   1274 C C   . LYS A 1 221 ? 161.777 157.211 149.871 1.00 62.19  ? 221 LYS A C   1 
ATOM   1275 O O   . LYS A 1 221 ? 161.103 156.704 148.968 1.00 62.19  ? 221 LYS A O   1 
ATOM   1276 C CB  . LYS A 1 221 ? 160.982 157.030 152.218 1.00 62.19  ? 221 LYS A CB  1 
ATOM   1277 C CG  . LYS A 1 221 ? 159.522 156.879 151.836 1.00 62.19  ? 221 LYS A CG  1 
ATOM   1278 C CD  . LYS A 1 221 ? 158.646 157.423 152.936 1.00 62.19  ? 221 LYS A CD  1 
ATOM   1279 C CE  . LYS A 1 221 ? 157.179 157.421 152.588 1.00 62.19  ? 221 LYS A CE  1 
ATOM   1280 N NZ  . LYS A 1 221 ? 156.639 156.053 152.494 1.00 62.19  ? 221 LYS A NZ  1 
ATOM   1281 N N   . VAL A 1 222 ? 162.338 158.415 149.749 1.00 64.58  ? 222 VAL A N   1 
ATOM   1282 C CA  . VAL A 1 222 ? 162.184 159.176 148.514 1.00 64.58  ? 222 VAL A CA  1 
ATOM   1283 C C   . VAL A 1 222 ? 162.805 158.439 147.347 1.00 64.58  ? 222 VAL A C   1 
ATOM   1284 O O   . VAL A 1 222 ? 162.196 158.332 146.283 1.00 64.58  ? 222 VAL A O   1 
ATOM   1285 C CB  . VAL A 1 222 ? 162.786 160.580 148.660 1.00 64.58  ? 222 VAL A CB  1 
ATOM   1286 C CG1 . VAL A 1 222 ? 162.957 161.202 147.307 1.00 64.58  ? 222 VAL A CG1 1 
ATOM   1287 C CG2 . VAL A 1 222 ? 161.881 161.436 149.491 1.00 64.58  ? 222 VAL A CG2 1 
ATOM   1288 N N   . PHE A 1 223 ? 164.011 157.910 147.519 1.00 67.19  ? 223 PHE A N   1 
ATOM   1289 C CA  . PHE A 1 223 ? 164.640 157.129 146.468 1.00 67.19  ? 223 PHE A CA  1 
ATOM   1290 C C   . PHE A 1 223 ? 163.839 155.889 146.138 1.00 67.19  ? 223 PHE A C   1 
ATOM   1291 O O   . PHE A 1 223 ? 163.688 155.546 144.960 1.00 67.19  ? 223 PHE A O   1 
ATOM   1292 C CB  . PHE A 1 223 ? 166.049 156.736 146.888 1.00 67.19  ? 223 PHE A CB  1 
ATOM   1293 C CG  . PHE A 1 223 ? 166.658 155.670 146.041 1.00 67.19  ? 223 PHE A CG  1 
ATOM   1294 C CD1 . PHE A 1 223 ? 167.200 155.976 144.815 1.00 67.19  ? 223 PHE A CD1 1 
ATOM   1295 C CD2 . PHE A 1 223 ? 166.715 154.366 146.482 1.00 67.19  ? 223 PHE A CD2 1 
ATOM   1296 C CE1 . PHE A 1 223 ? 167.768 155.005 144.039 1.00 67.19  ? 223 PHE A CE1 1 
ATOM   1297 C CE2 . PHE A 1 223 ? 167.283 153.391 145.705 1.00 67.19  ? 223 PHE A CE2 1 
ATOM   1298 C CZ  . PHE A 1 223 ? 167.809 153.712 144.484 1.00 67.19  ? 223 PHE A CZ  1 
ATOM   1299 N N   . TYR A 1 224 ? 163.306 155.215 147.150 1.00 61.64  ? 224 TYR A N   1 
ATOM   1300 C CA  . TYR A 1 224 ? 162.649 153.945 146.899 1.00 61.64  ? 224 TYR A CA  1 
ATOM   1301 C C   . TYR A 1 224 ? 161.358 154.166 146.124 1.00 61.64  ? 224 TYR A C   1 
ATOM   1302 O O   . TYR A 1 224 ? 161.097 153.492 145.121 1.00 61.64  ? 224 TYR A O   1 
ATOM   1303 C CB  . TYR A 1 224 ? 162.359 153.265 148.226 1.00 61.64  ? 224 TYR A CB  1 
ATOM   1304 C CG  . TYR A 1 224 ? 162.392 151.779 148.159 1.00 61.64  ? 224 TYR A CG  1 
ATOM   1305 C CD1 . TYR A 1 224 ? 163.587 151.113 148.329 1.00 61.64  ? 224 TYR A CD1 1 
ATOM   1306 C CD2 . TYR A 1 224 ? 161.273 151.045 147.857 1.00 61.64  ? 224 TYR A CD2 1 
ATOM   1307 C CE1 . TYR A 1 224 ? 163.658 149.769 148.267 1.00 61.64  ? 224 TYR A CE1 1 
ATOM   1308 C CE2 . TYR A 1 224 ? 161.338 149.684 147.779 1.00 61.64  ? 224 TYR A CE2 1 
ATOM   1309 C CZ  . TYR A 1 224 ? 162.537 149.056 147.986 1.00 61.64  ? 224 TYR A CZ  1 
ATOM   1310 O OH  . TYR A 1 224 ? 162.627 147.696 147.913 1.00 61.64  ? 224 TYR A OH  1 
ATOM   1311 N N   . LEU A 1 225 ? 160.564 155.150 146.541 1.00 64.02  ? 225 LEU A N   1 
ATOM   1312 C CA  . LEU A 1 225 ? 159.340 155.477 145.825 1.00 64.02  ? 225 LEU A CA  1 
ATOM   1313 C C   . LEU A 1 225 ? 159.594 156.172 144.495 1.00 64.02  ? 225 LEU A C   1 
ATOM   1314 O O   . LEU A 1 225 ? 158.780 156.038 143.585 1.00 64.02  ? 225 LEU A O   1 
ATOM   1315 C CB  . LEU A 1 225 ? 158.432 156.342 146.693 1.00 64.02  ? 225 LEU A CB  1 
ATOM   1316 C CG  . LEU A 1 225 ? 157.767 155.629 147.861 1.00 64.02  ? 225 LEU A CG  1 
ATOM   1317 C CD1 . LEU A 1 225 ? 156.657 156.478 148.404 1.00 64.02  ? 225 LEU A CD1 1 
ATOM   1318 C CD2 . LEU A 1 225 ? 157.228 154.308 147.400 1.00 64.02  ? 225 LEU A CD2 1 
ATOM   1319 N N   . GLY A 1 226 ? 160.698 156.901 144.345 1.00 66.16  ? 226 GLY A N   1 
ATOM   1320 C CA  . GLY A 1 226 ? 161.044 157.417 143.036 1.00 66.16  ? 226 GLY A CA  1 
ATOM   1321 C C   . GLY A 1 226 ? 161.334 156.307 142.047 1.00 66.16  ? 226 GLY A C   1 
ATOM   1322 O O   . GLY A 1 226 ? 160.861 156.337 140.911 1.00 66.16  ? 226 GLY A O   1 
ATOM   1323 N N   . GLN A 1 227 ? 162.114 155.310 142.463 1.00 72.07  ? 227 GLN A N   1 
ATOM   1324 C CA  . GLN A 1 227 ? 162.311 154.146 141.607 1.00 72.07  ? 227 GLN A CA  1 
ATOM   1325 C C   . GLN A 1 227 ? 160.990 153.464 141.299 1.00 72.07  ? 227 GLN A C   1 
ATOM   1326 O O   . GLN A 1 227 ? 160.747 153.053 140.159 1.00 72.07  ? 227 GLN A O   1 
ATOM   1327 C CB  . GLN A 1 227 ? 163.272 153.157 142.258 1.00 72.07  ? 227 GLN A CB  1 
ATOM   1328 C CG  . GLN A 1 227 ? 164.696 153.624 142.310 1.00 72.07  ? 227 GLN A CG  1 
ATOM   1329 C CD  . GLN A 1 227 ? 165.293 153.762 140.935 1.00 72.07  ? 227 GLN A CD  1 
ATOM   1330 O OE1 . GLN A 1 227 ? 165.527 154.867 140.456 1.00 72.07  ? 227 GLN A OE1 1 
ATOM   1331 N NE2 . GLN A 1 227 ? 165.550 152.636 140.289 1.00 72.07  ? 227 GLN A NE2 1 
ATOM   1332 N N   . ALA A 1 228 ? 160.127 153.321 142.304 1.00 68.90  ? 228 ALA A N   1 
ATOM   1333 C CA  . ALA A 1 228 ? 158.830 152.699 142.065 1.00 68.90  ? 228 ALA A CA  1 
ATOM   1334 C C   . ALA A 1 228 ? 158.049 153.456 141.001 1.00 68.90  ? 228 ALA A C   1 
ATOM   1335 O O   . ALA A 1 228 ? 157.521 152.857 140.059 1.00 68.90  ? 228 ALA A O   1 
ATOM   1336 C CB  . ALA A 1 228 ? 158.033 152.626 143.363 1.00 68.90  ? 228 ALA A CB  1 
ATOM   1337 N N   . ALA A 1 229 ? 157.978 154.781 141.127 1.00 71.37  ? 229 ALA A N   1 
ATOM   1338 C CA  . ALA A 1 229 ? 157.226 155.589 140.177 1.00 71.37  ? 229 ALA A CA  1 
ATOM   1339 C C   . ALA A 1 229 ? 157.827 155.512 138.784 1.00 71.37  ? 229 ALA A C   1 
ATOM   1340 O O   . ALA A 1 229 ? 157.107 155.368 137.792 1.00 71.37  ? 229 ALA A O   1 
ATOM   1341 C CB  . ALA A 1 229 ? 157.176 157.035 140.652 1.00 71.37  ? 229 ALA A CB  1 
ATOM   1342 N N   . PHE A 1 230 ? 159.151 155.599 138.691 1.00 76.67  ? 230 PHE A N   1 
ATOM   1343 C CA  . PHE A 1 230 ? 159.805 155.578 137.389 1.00 76.67  ? 230 PHE A CA  1 
ATOM   1344 C C   . PHE A 1 230 ? 159.563 154.262 136.667 1.00 76.67  ? 230 PHE A C   1 
ATOM   1345 O O   . PHE A 1 230 ? 159.209 154.249 135.485 1.00 76.67  ? 230 PHE A O   1 
ATOM   1346 C CB  . PHE A 1 230 ? 161.298 155.822 137.557 1.00 76.67  ? 230 PHE A CB  1 
ATOM   1347 C CG  . PHE A 1 230 ? 162.066 155.708 136.291 1.00 76.67  ? 230 PHE A CG  1 
ATOM   1348 C CD1 . PHE A 1 230 ? 162.083 156.745 135.388 1.00 76.67  ? 230 PHE A CD1 1 
ATOM   1349 C CD2 . PHE A 1 230 ? 162.777 154.569 136.001 1.00 76.67  ? 230 PHE A CD2 1 
ATOM   1350 C CE1 . PHE A 1 230 ? 162.788 156.646 134.219 1.00 76.67  ? 230 PHE A CE1 1 
ATOM   1351 C CE2 . PHE A 1 230 ? 163.485 154.466 134.832 1.00 76.67  ? 230 PHE A CE2 1 
ATOM   1352 C CZ  . PHE A 1 230 ? 163.489 155.507 133.941 1.00 76.67  ? 230 PHE A CZ  1 
ATOM   1353 N N   . TRP A 1 231 ? 159.745 153.140 137.358 1.00 78.01  ? 231 TRP A N   1 
ATOM   1354 C CA  . TRP A 1 231 ? 159.566 151.865 136.677 1.00 78.01  ? 231 TRP A CA  1 
ATOM   1355 C C   . TRP A 1 231 ? 158.098 151.568 136.405 1.00 78.01  ? 231 TRP A C   1 
ATOM   1356 O O   . TRP A 1 231 ? 157.776 150.947 135.386 1.00 78.01  ? 231 TRP A O   1 
ATOM   1357 C CB  . TRP A 1 231 ? 160.210 150.741 137.474 1.00 78.01  ? 231 TRP A CB  1 
ATOM   1358 C CG  . TRP A 1 231 ? 161.688 150.786 137.436 1.00 78.01  ? 231 TRP A CG  1 
ATOM   1359 C CD1 . TRP A 1 231 ? 162.521 150.922 138.493 1.00 78.01  ? 231 TRP A CD1 1 
ATOM   1360 C CD2 . TRP A 1 231 ? 162.519 150.719 136.276 1.00 78.01  ? 231 TRP A CD2 1 
ATOM   1361 N NE1 . TRP A 1 231 ? 163.823 150.935 138.074 1.00 78.01  ? 231 TRP A NE1 1 
ATOM   1362 C CE2 . TRP A 1 231 ? 163.846 150.815 136.712 1.00 78.01  ? 231 TRP A CE2 1 
ATOM   1363 C CE3 . TRP A 1 231 ? 162.269 150.586 134.912 1.00 78.01  ? 231 TRP A CE3 1 
ATOM   1364 C CZ2 . TRP A 1 231 ? 164.921 150.783 135.836 1.00 78.01  ? 231 TRP A CZ2 1 
ATOM   1365 C CZ3 . TRP A 1 231 ? 163.335 150.555 134.046 1.00 78.01  ? 231 TRP A CZ3 1 
ATOM   1366 C CH2 . TRP A 1 231 ? 164.644 150.651 134.509 1.00 78.01  ? 231 TRP A CH2 1 
ATOM   1367 N N   . ALA A 1 232 ? 157.191 152.013 137.273 1.00 78.55  ? 232 ALA A N   1 
ATOM   1368 C CA  . ALA A 1 232 ? 155.776 151.873 136.964 1.00 78.55  ? 232 ALA A CA  1 
ATOM   1369 C C   . ALA A 1 232 ? 155.419 152.659 135.714 1.00 78.55  ? 232 ALA A C   1 
ATOM   1370 O O   . ALA A 1 232 ? 154.655 152.187 134.868 1.00 78.55  ? 232 ALA A O   1 
ATOM   1371 C CB  . ALA A 1 232 ? 154.929 152.331 138.148 1.00 78.55  ? 232 ALA A CB  1 
ATOM   1372 N N   . GLN A 1 233 ? 155.969 153.860 135.574 1.00 79.89  ? 233 GLN A N   1 
ATOM   1373 C CA  . GLN A 1 233 ? 155.744 154.639 134.367 1.00 79.89  ? 233 GLN A CA  1 
ATOM   1374 C C   . GLN A 1 233 ? 156.355 153.997 133.133 1.00 79.89  ? 233 GLN A C   1 
ATOM   1375 O O   . GLN A 1 233 ? 155.771 154.079 132.049 1.00 79.89  ? 233 GLN A O   1 
ATOM   1376 C CB  . GLN A 1 233 ? 156.304 156.037 134.550 1.00 79.89  ? 233 GLN A CB  1 
ATOM   1377 C CG  . GLN A 1 233 ? 155.771 157.011 133.574 1.00 79.89  ? 233 GLN A CG  1 
ATOM   1378 C CD  . GLN A 1 233 ? 156.785 157.337 132.527 1.00 79.89  ? 233 GLN A CD  1 
ATOM   1379 O OE1 . GLN A 1 233 ? 157.975 157.099 132.710 1.00 79.89  ? 233 GLN A OE1 1 
ATOM   1380 N NE2 . GLN A 1 233 ? 156.326 157.877 131.411 1.00 79.89  ? 233 GLN A NE2 1 
ATOM   1381 N N   . GLN A 1 234 ? 157.522 153.375 133.264 1.00 84.45  ? 234 GLN A N   1 
ATOM   1382 C CA  . GLN A 1 234 ? 158.087 152.651 132.133 1.00 84.45  ? 234 GLN A CA  1 
ATOM   1383 C C   . GLN A 1 234 ? 157.160 151.526 131.697 1.00 84.45  ? 234 GLN A C   1 
ATOM   1384 O O   . GLN A 1 234 ? 156.910 151.343 130.503 1.00 84.45  ? 234 GLN A O   1 
ATOM   1385 C CB  . GLN A 1 234 ? 159.460 152.095 132.493 1.00 84.45  ? 234 GLN A CB  1 
ATOM   1386 C CG  . GLN A 1 234 ? 160.530 153.141 132.610 1.00 84.45  ? 234 GLN A CG  1 
ATOM   1387 C CD  . GLN A 1 234 ? 161.033 153.625 131.280 1.00 84.45  ? 234 GLN A CD  1 
ATOM   1388 O OE1 . GLN A 1 234 ? 160.285 153.717 130.310 1.00 84.45  ? 234 GLN A OE1 1 
ATOM   1389 N NE2 . GLN A 1 234 ? 162.316 153.941 131.222 1.00 84.45  ? 234 GLN A NE2 1 
ATOM   1390 N N   . ALA A 1 235 ? 156.633 150.767 132.656 1.00 85.91  ? 235 ALA A N   1 
ATOM   1391 C CA  . ALA A 1 235 ? 155.696 149.703 132.309 1.00 85.91  ? 235 ALA A CA  1 
ATOM   1392 C C   . ALA A 1 235 ? 154.436 150.271 131.669 1.00 85.91  ? 235 ALA A C   1 
ATOM   1393 O O   . ALA A 1 235 ? 153.882 149.681 130.735 1.00 85.91  ? 235 ALA A O   1 
ATOM   1394 C CB  . ALA A 1 235 ? 155.345 148.884 133.548 1.00 85.91  ? 235 ALA A CB  1 
ATOM   1395 N N   . CYS A 1 236 ? 153.962 151.410 132.171 1.00 90.32  ? 236 CYS A N   1 
ATOM   1396 C CA  . CYS A 1 236 ? 152.776 152.039 131.603 1.00 90.32  ? 236 CYS A CA  1 
ATOM   1397 C C   . CYS A 1 236 ? 153.006 152.444 130.155 1.00 90.32  ? 236 CYS A C   1 
ATOM   1398 O O   . CYS A 1 236 ? 152.130 152.250 129.307 1.00 90.32  ? 236 CYS A O   1 
ATOM   1399 C CB  . CYS A 1 236 ? 152.375 153.247 132.449 1.00 90.32  ? 236 CYS A CB  1 
ATOM   1400 S SG  . CYS A 1 236 ? 151.024 154.245 131.794 1.00 90.32  ? 236 CYS A SG  1 
ATOM   1401 N N   . ILE A 1 237 ? 154.171 153.006 129.851 1.00 92.39  ? 237 ILE A N   1 
ATOM   1402 C CA  . ILE A 1 237 ? 154.498 153.362 128.474 1.00 92.39  ? 237 ILE A CA  1 
ATOM   1403 C C   . ILE A 1 237 ? 154.608 152.106 127.625 1.00 92.39  ? 237 ILE A C   1 
ATOM   1404 O O   . ILE A 1 237 ? 154.183 152.089 126.468 1.00 92.39  ? 237 ILE A O   1 
ATOM   1405 C CB  . ILE A 1 237 ? 155.786 154.195 128.392 1.00 92.39  ? 237 ILE A CB  1 
ATOM   1406 C CG1 . ILE A 1 237 ? 155.612 155.492 129.165 1.00 92.39  ? 237 ILE A CG1 1 
ATOM   1407 C CG2 . ILE A 1 237 ? 156.142 154.485 126.959 1.00 92.39  ? 237 ILE A CG2 1 
ATOM   1408 C CD1 . ILE A 1 237 ? 154.502 156.347 128.616 1.00 92.39  ? 237 ILE A CD1 1 
ATOM   1409 N N   . LEU A 1 238 ? 155.162 151.042 128.193 1.00 95.40  ? 238 LEU A N   1 
ATOM   1410 C CA  . LEU A 1 238 ? 155.342 149.808 127.439 1.00 95.40  ? 238 LEU A CA  1 
ATOM   1411 C C   . LEU A 1 238 ? 154.007 149.190 127.031 1.00 95.40  ? 238 LEU A C   1 
ATOM   1412 O O   . LEU A 1 238 ? 153.748 149.003 125.840 1.00 95.40  ? 238 LEU A O   1 
ATOM   1413 C CB  . LEU A 1 238 ? 156.179 148.825 128.260 1.00 95.40  ? 238 LEU A CB  1 
ATOM   1414 C CG  . LEU A 1 238 ? 156.460 147.445 127.681 1.00 95.40  ? 238 LEU A CG  1 
ATOM   1415 C CD1 . LEU A 1 238 ? 157.825 147.000 128.135 1.00 95.40  ? 238 LEU A CD1 1 
ATOM   1416 C CD2 . LEU A 1 238 ? 155.414 146.468 128.150 1.00 95.40  ? 238 LEU A CD2 1 
ATOM   1417 N N   . VAL A 1 239 ? 153.150 148.868 128.006 1.00 98.56  ? 239 VAL A N   1 
ATOM   1418 C CA  . VAL A 1 239 ? 151.914 148.155 127.681 1.00 98.56  ? 239 VAL A CA  1 
ATOM   1419 C C   . VAL A 1 239 ? 150.975 149.026 126.860 1.00 98.56  ? 239 VAL A C   1 
ATOM   1420 O O   . VAL A 1 239 ? 150.270 148.525 125.978 1.00 98.56  ? 239 VAL A O   1 
ATOM   1421 C CB  . VAL A 1 239 ? 151.220 147.629 128.954 1.00 98.56  ? 239 VAL A CB  1 
ATOM   1422 C CG1 . VAL A 1 239 ? 152.109 146.633 129.672 1.00 98.56  ? 239 VAL A CG1 1 
ATOM   1423 C CG2 . VAL A 1 239 ? 150.832 148.764 129.874 1.00 98.56  ? 239 VAL A CG2 1 
ATOM   1424 N N   . LEU A 1 240 ? 150.939 150.327 127.129 1.00 101.41 ? 240 LEU A N   1 
ATOM   1425 C CA  . LEU A 1 240 ? 150.187 151.265 126.300 1.00 101.41 ? 240 LEU A CA  1 
ATOM   1426 C C   . LEU A 1 240 ? 151.015 151.498 125.048 1.00 101.41 ? 240 LEU A C   1 
ATOM   1427 O O   . LEU A 1 240 ? 151.837 152.414 124.994 1.00 101.41 ? 240 LEU A O   1 
ATOM   1428 C CB  . LEU A 1 240 ? 149.905 152.563 127.051 1.00 101.41 ? 240 LEU A CB  1 
ATOM   1429 C CG  . LEU A 1 240 ? 149.189 153.701 126.317 1.00 101.41 ? 240 LEU A CG  1 
ATOM   1430 C CD1 . LEU A 1 240 ? 148.102 154.297 127.177 1.00 101.41 ? 240 LEU A CD1 1 
ATOM   1431 C CD2 . LEU A 1 240 ? 150.163 154.787 125.926 1.00 101.41 ? 240 LEU A CD2 1 
ATOM   1432 N N   . GLN A 1 241 ? 150.818 150.653 124.043 1.00 111.28 ? 241 GLN A N   1 
ATOM   1433 C CA  . GLN A 1 241 ? 151.605 150.747 122.821 1.00 111.28 ? 241 GLN A CA  1 
ATOM   1434 C C   . GLN A 1 241 ? 151.272 152.042 122.101 1.00 111.28 ? 241 GLN A C   1 
ATOM   1435 O O   . GLN A 1 241 ? 150.224 152.157 121.459 1.00 111.28 ? 241 GLN A O   1 
ATOM   1436 C CB  . GLN A 1 241 ? 151.338 149.545 121.923 1.00 111.28 ? 241 GLN A CB  1 
ATOM   1437 C CG  . GLN A 1 241 ? 151.551 148.191 122.573 1.00 111.28 ? 241 GLN A CG  1 
ATOM   1438 C CD  . GLN A 1 241 ? 153.004 147.883 122.885 1.00 111.28 ? 241 GLN A CD  1 
ATOM   1439 O OE1 . GLN A 1 241 ? 153.848 148.773 122.990 1.00 111.28 ? 241 GLN A OE1 1 
ATOM   1440 N NE2 . GLN A 1 241 ? 153.303 146.603 123.020 1.00 111.28 ? 241 GLN A NE2 1 
ATOM   1441 N N   . LEU A 1 242 ? 152.161 153.021 122.208 1.00 119.03 ? 242 LEU A N   1 
ATOM   1442 C CA  . LEU A 1 242 ? 152.017 154.234 121.421 1.00 119.03 ? 242 LEU A CA  1 
ATOM   1443 C C   . LEU A 1 242 ? 152.617 153.947 120.053 1.00 119.03 ? 242 LEU A C   1 
ATOM   1444 O O   . LEU A 1 242 ? 151.967 154.148 119.023 1.00 119.03 ? 242 LEU A O   1 
ATOM   1445 C CB  . LEU A 1 242 ? 152.699 155.415 122.114 1.00 119.03 ? 242 LEU A CB  1 
ATOM   1446 C CG  . LEU A 1 242 ? 152.236 156.818 121.725 1.00 119.03 ? 242 LEU A CG  1 
ATOM   1447 C CD1 . LEU A 1 242 ? 150.802 157.033 122.177 1.00 119.03 ? 242 LEU A CD1 1 
ATOM   1448 C CD2 . LEU A 1 242 ? 153.153 157.878 122.316 1.00 119.03 ? 242 LEU A CD2 1 
ATOM   1449 N N   . GLU A 1 243 ? 153.853 153.451 120.047 1.00 125.23 ? 243 GLU A N   1 
ATOM   1450 C CA  . GLU A 1 243 ? 154.494 152.887 118.864 1.00 125.23 ? 243 GLU A CA  1 
ATOM   1451 C C   . GLU A 1 243 ? 155.245 151.638 119.298 1.00 125.23 ? 243 GLU A C   1 
ATOM   1452 O O   . GLU A 1 243 ? 155.882 151.638 120.357 1.00 125.23 ? 243 GLU A O   1 
ATOM   1453 C CB  . GLU A 1 243 ? 155.445 153.891 118.208 1.00 125.23 ? 243 GLU A CB  1 
ATOM   1454 C CG  . GLU A 1 243 ? 154.826 154.697 117.076 1.00 125.23 ? 243 GLU A CG  1 
ATOM   1455 C CD  . GLU A 1 243 ? 153.904 155.791 117.572 1.00 125.23 ? 243 GLU A CD  1 
ATOM   1456 O OE1 . GLU A 1 243 ? 152.932 156.122 116.862 1.00 125.23 ? 243 GLU A OE1 1 
ATOM   1457 O OE2 . GLU A 1 243 ? 154.144 156.313 118.680 1.00 125.23 ? 243 GLU A OE2 1 
ATOM   1458 N N   . LYS A 1 244 ? 155.141 150.561 118.528 1.00 127.15 ? 244 LYS A N   1 
ATOM   1459 C CA  . LYS A 1 244 ? 155.797 149.310 118.896 1.00 127.15 ? 244 LYS A CA  1 
ATOM   1460 C C   . LYS A 1 244 ? 157.226 149.202 118.381 1.00 127.15 ? 244 LYS A C   1 
ATOM   1461 O O   . LYS A 1 244 ? 157.450 149.158 117.171 1.00 127.15 ? 244 LYS A O   1 
ATOM   1462 C CB  . LYS A 1 244 ? 154.975 148.114 118.405 1.00 127.15 ? 244 LYS A CB  1 
ATOM   1463 C CG  . LYS A 1 244 ? 155.441 146.774 118.951 1.00 127.15 ? 244 LYS A CG  1 
ATOM   1464 C CD  . LYS A 1 244 ? 155.080 145.638 118.008 1.00 127.15 ? 244 LYS A CD  1 
ATOM   1465 C CE  . LYS A 1 244 ? 156.151 144.559 118.008 1.00 127.15 ? 244 LYS A CE  1 
ATOM   1466 N NZ  . LYS A 1 244 ? 156.142 143.768 119.269 1.00 127.15 ? 244 LYS A NZ  1 
ATOM   1467 N N   . PRO A 1 245 ? 158.205 149.160 119.300 1.00 130.41 ? 245 PRO A N   1 
ATOM   1468 C CA  . PRO A 1 245 ? 159.600 149.039 118.870 1.00 130.41 ? 245 PRO A CA  1 
ATOM   1469 C C   . PRO A 1 245 ? 159.963 147.619 118.472 1.00 130.41 ? 245 PRO A C   1 
ATOM   1470 O O   . PRO A 1 245 ? 159.134 146.707 118.536 1.00 130.41 ? 245 PRO A O   1 
ATOM   1471 C CB  . PRO A 1 245 ? 160.374 149.495 120.120 1.00 130.41 ? 245 PRO A CB  1 
ATOM   1472 C CG  . PRO A 1 245 ? 159.329 150.297 120.893 1.00 130.41 ? 245 PRO A CG  1 
ATOM   1473 C CD  . PRO A 1 245 ? 158.169 149.376 120.751 1.00 130.41 ? 245 PRO A CD  1 
ATOM   1474 N N   . ARG A 1 246 ? 161.213 147.473 118.042 1.00 131.90 ? 246 ARG A N   1 
ATOM   1475 C CA  . ARG A 1 246 ? 161.783 146.225 117.534 1.00 131.90 ? 246 ARG A CA  1 
ATOM   1476 C C   . ARG A 1 246 ? 161.747 144.966 118.402 1.00 131.90 ? 246 ARG A C   1 
ATOM   1477 O O   . ARG A 1 246 ? 160.906 144.804 119.287 1.00 131.90 ? 246 ARG A O   1 
ATOM   1478 C CB  . ARG A 1 246 ? 163.223 146.468 117.064 1.00 131.90 ? 246 ARG A CB  1 
ATOM   1479 C CG  . ARG A 1 246 ? 163.329 147.034 115.657 1.00 131.90 ? 246 ARG A CG  1 
ATOM   1480 C CD  . ARG A 1 246 ? 164.159 146.129 114.760 1.00 131.90 ? 246 ARG A CD  1 
ATOM   1481 N NE  . ARG A 1 246 ? 163.923 146.398 113.344 1.00 131.90 ? 246 ARG A NE  1 
ATOM   1482 C CZ  . ARG A 1 246 ? 164.842 146.879 112.512 1.00 131.90 ? 246 ARG A CZ  1 
ATOM   1483 N NH1 . ARG A 1 246 ? 166.063 147.146 112.953 1.00 131.90 ? 246 ARG A NH1 1 
ATOM   1484 N NH2 . ARG A 1 246 ? 164.538 147.093 111.239 1.00 131.90 ? 246 ARG A NH2 1 
ATOM   1485 N N   . LYS A 1 247 ? 162.698 144.086 118.105 1.00 128.69 ? 247 LYS A N   1 
ATOM   1486 C CA  . LYS A 1 247 ? 162.861 142.781 118.737 1.00 128.69 ? 247 LYS A CA  1 
ATOM   1487 C C   . LYS A 1 247 ? 162.811 142.770 120.258 1.00 128.69 ? 247 LYS A C   1 
ATOM   1488 O O   . LYS A 1 247 ? 162.147 141.909 120.844 1.00 128.69 ? 247 LYS A O   1 
ATOM   1489 C CB  . LYS A 1 247 ? 164.191 142.179 118.283 1.00 128.69 ? 247 LYS A CB  1 
ATOM   1490 C CG  . LYS A 1 247 ? 164.679 141.008 119.114 1.00 128.69 ? 247 LYS A CG  1 
ATOM   1491 C CD  . LYS A 1 247 ? 166.031 140.534 118.613 1.00 128.69 ? 247 LYS A CD  1 
ATOM   1492 C CE  . LYS A 1 247 ? 167.093 141.601 118.836 1.00 128.69 ? 247 LYS A CE  1 
ATOM   1493 N NZ  . LYS A 1 247 ? 168.436 141.184 118.350 1.00 128.69 ? 247 LYS A NZ  1 
ATOM   1494 N N   . ASP A 1 248 ? 163.496 143.710 120.912 1.00 122.12 ? 248 ASP A N   1 
ATOM   1495 C CA  . ASP A 1 248 ? 163.763 143.552 122.338 1.00 122.12 ? 248 ASP A CA  1 
ATOM   1496 C C   . ASP A 1 248 ? 162.511 143.616 123.206 1.00 122.12 ? 248 ASP A C   1 
ATOM   1497 O O   . ASP A 1 248 ? 162.615 143.449 124.425 1.00 122.12 ? 248 ASP A O   1 
ATOM   1498 C CB  . ASP A 1 248 ? 164.777 144.598 122.810 1.00 122.12 ? 248 ASP A CB  1 
ATOM   1499 C CG  . ASP A 1 248 ? 164.271 146.017 122.666 1.00 122.12 ? 248 ASP A CG  1 
ATOM   1500 O OD1 . ASP A 1 248 ? 163.171 146.218 122.109 1.00 122.12 ? 248 ASP A OD1 1 
ATOM   1501 O OD2 . ASP A 1 248 ? 164.973 146.942 123.124 1.00 122.12 ? 248 ASP A OD2 1 
ATOM   1502 N N   . HIS A 1 249 ? 161.336 143.815 122.610 1.00 117.82 ? 249 HIS A N   1 
ATOM   1503 C CA  . HIS A 1 249 ? 160.118 144.154 123.338 1.00 117.82 ? 249 HIS A CA  1 
ATOM   1504 C C   . HIS A 1 249 ? 159.806 143.260 124.535 1.00 117.82 ? 249 HIS A C   1 
ATOM   1505 O O   . HIS A 1 249 ? 159.757 143.748 125.667 1.00 117.82 ? 249 HIS A O   1 
ATOM   1506 C CB  . HIS A 1 249 ? 158.929 144.137 122.381 1.00 117.82 ? 249 HIS A CB  1 
ATOM   1507 C CG  . HIS A 1 249 ? 157.684 144.732 122.958 1.00 117.82 ? 249 HIS A CG  1 
ATOM   1508 N ND1 . HIS A 1 249 ? 156.502 144.029 123.056 1.00 117.82 ? 249 HIS A ND1 1 
ATOM   1509 C CD2 . HIS A 1 249 ? 157.433 145.962 123.464 1.00 117.82 ? 249 HIS A CD2 1 
ATOM   1510 C CE1 . HIS A 1 249 ? 155.580 144.799 123.602 1.00 117.82 ? 249 HIS A CE1 1 
ATOM   1511 N NE2 . HIS A 1 249 ? 156.118 145.978 123.856 1.00 117.82 ? 249 HIS A NE2 1 
ATOM   1512 N N   . ASN A 1 250 ? 159.607 141.958 124.312 1.00 112.27 ? 250 ASN A N   1 
ATOM   1513 C CA  . ASN A 1 250 ? 158.985 141.119 125.338 1.00 112.27 ? 250 ASN A CA  1 
ATOM   1514 C C   . ASN A 1 250 ? 159.908 140.788 126.509 1.00 112.27 ? 250 ASN A C   1 
ATOM   1515 O O   . ASN A 1 250 ? 159.443 140.756 127.655 1.00 112.27 ? 250 ASN A O   1 
ATOM   1516 C CB  . ASN A 1 250 ? 158.454 139.832 124.712 1.00 112.27 ? 250 ASN A CB  1 
ATOM   1517 C CG  . ASN A 1 250 ? 157.040 139.987 124.192 1.00 112.27 ? 250 ASN A CG  1 
ATOM   1518 O OD1 . ASN A 1 250 ? 156.314 140.893 124.602 1.00 112.27 ? 250 ASN A OD1 1 
ATOM   1519 N ND2 . ASN A 1 250 ? 156.637 139.099 123.292 1.00 112.27 ? 250 ASN A ND2 1 
ATOM   1520 N N   . GLU A 1 251 ? 161.197 140.626 126.230 1.00 109.94 ? 251 GLU A N   1 
ATOM   1521 C CA  . GLU A 1 251 ? 162.171 140.380 127.281 1.00 109.94 ? 251 GLU A CA  1 
ATOM   1522 C C   . GLU A 1 251 ? 162.195 141.639 128.141 1.00 109.94 ? 251 GLU A C   1 
ATOM   1523 O O   . GLU A 1 251 ? 162.273 141.567 129.368 1.00 109.94 ? 251 GLU A O   1 
ATOM   1524 C CB  . GLU A 1 251 ? 163.553 140.110 126.688 1.00 109.94 ? 251 GLU A CB  1 
ATOM   1525 C CG  . GLU A 1 251 ? 164.665 140.024 127.720 1.00 109.94 ? 251 GLU A CG  1 
ATOM   1526 C CD  . GLU A 1 251 ? 166.031 139.836 127.090 1.00 109.94 ? 251 GLU A CD  1 
ATOM   1527 O OE1 . GLU A 1 251 ? 166.730 138.869 127.459 1.00 109.94 ? 251 GLU A OE1 1 
ATOM   1528 O OE2 . GLU A 1 251 ? 166.405 140.655 126.225 1.00 109.94 ? 251 GLU A OE2 1 
ATOM   1529 N N   . LEU A 1 252 ? 162.126 142.794 127.481 1.00 106.38 ? 252 LEU A N   1 
ATOM   1530 C CA  . LEU A 1 252 ? 162.097 144.079 128.168 1.00 106.38 ? 252 LEU A CA  1 
ATOM   1531 C C   . LEU A 1 252 ? 160.875 144.186 129.071 1.00 106.38 ? 252 LEU A C   1 
ATOM   1532 O O   . LEU A 1 252 ? 160.963 144.683 130.202 1.00 106.38 ? 252 LEU A O   1 
ATOM   1533 C CB  . LEU A 1 252 ? 162.112 145.209 127.146 1.00 106.38 ? 252 LEU A CB  1 
ATOM   1534 C CG  . LEU A 1 252 ? 162.704 146.519 127.631 1.00 106.38 ? 252 LEU A CG  1 
ATOM   1535 C CD1 . LEU A 1 252 ? 164.188 146.325 127.897 1.00 106.38 ? 252 LEU A CD1 1 
ATOM   1536 C CD2 . LEU A 1 252 ? 162.462 147.608 126.604 1.00 106.38 ? 252 LEU A CD2 1 
ATOM   1537 N N   . THR A 1 253 ? 159.717 143.734 128.584 1.00 104.10 ? 253 THR A N   1 
ATOM   1538 C CA  . THR A 1 253 ? 158.549 143.656 129.453 1.00 104.10 ? 253 THR A CA  1 
ATOM   1539 C C   . THR A 1 253 ? 158.804 142.780 130.659 1.00 104.10 ? 253 THR A C   1 
ATOM   1540 O O   . THR A 1 253 ? 158.394 143.140 131.763 1.00 104.10 ? 253 THR A O   1 
ATOM   1541 C CB  . THR A 1 253 ? 157.335 143.082 128.725 1.00 104.10 ? 253 THR A CB  1 
ATOM   1542 O OG1 . THR A 1 253 ? 157.464 141.657 128.654 1.00 104.10 ? 253 THR A OG1 1 
ATOM   1543 C CG2 . THR A 1 253 ? 157.229 143.630 127.328 1.00 104.10 ? 253 THR A CG2 1 
ATOM   1544 N N   . PHE A 1 254 ? 159.453 141.636 130.462 1.00 96.15  ? 254 PHE A N   1 
ATOM   1545 C CA  . PHE A 1 254 ? 159.764 140.767 131.588 1.00 96.15  ? 254 PHE A CA  1 
ATOM   1546 C C   . PHE A 1 254 ? 160.661 141.481 132.588 1.00 96.15  ? 254 PHE A C   1 
ATOM   1547 O O   . PHE A 1 254 ? 160.481 141.357 133.806 1.00 96.15  ? 254 PHE A O   1 
ATOM   1548 C CB  . PHE A 1 254 ? 160.428 139.487 131.094 1.00 96.15  ? 254 PHE A CB  1 
ATOM   1549 C CG  . PHE A 1 254 ? 161.032 138.666 132.184 1.00 96.15  ? 254 PHE A CG  1 
ATOM   1550 C CD1 . PHE A 1 254 ? 160.251 137.800 132.920 1.00 96.15  ? 254 PHE A CD1 1 
ATOM   1551 C CD2 . PHE A 1 254 ? 162.373 138.770 132.484 1.00 96.15  ? 254 PHE A CD2 1 
ATOM   1552 C CE1 . PHE A 1 254 ? 160.800 137.044 133.926 1.00 96.15  ? 254 PHE A CE1 1 
ATOM   1553 C CE2 . PHE A 1 254 ? 162.921 138.024 133.489 1.00 96.15  ? 254 PHE A CE2 1 
ATOM   1554 C CZ  . PHE A 1 254 ? 162.139 137.158 134.211 1.00 96.15  ? 254 PHE A CZ  1 
ATOM   1555 N N   . HIS A 1 255 ? 161.645 142.227 132.088 1.00 94.78  ? 255 HIS A N   1 
ATOM   1556 C CA  . HIS A 1 255 ? 162.511 142.994 132.975 1.00 94.78  ? 255 HIS A CA  1 
ATOM   1557 C C   . HIS A 1 255 ? 161.733 144.013 133.791 1.00 94.78  ? 255 HIS A C   1 
ATOM   1558 O O   . HIS A 1 255 ? 161.921 144.100 135.008 1.00 94.78  ? 255 HIS A O   1 
ATOM   1559 C CB  . HIS A 1 255 ? 163.590 143.709 132.177 1.00 94.78  ? 255 HIS A CB  1 
ATOM   1560 C CG  . HIS A 1 255 ? 164.404 144.653 132.998 1.00 94.78  ? 255 HIS A CG  1 
ATOM   1561 N ND1 . HIS A 1 255 ? 164.078 145.984 133.135 1.00 94.78  ? 255 HIS A ND1 1 
ATOM   1562 C CD2 . HIS A 1 255 ? 165.520 144.458 133.739 1.00 94.78  ? 255 HIS A CD2 1 
ATOM   1563 C CE1 . HIS A 1 255 ? 164.963 146.571 133.917 1.00 94.78  ? 255 HIS A CE1 1 
ATOM   1564 N NE2 . HIS A 1 255 ? 165.848 145.668 134.298 1.00 94.78  ? 255 HIS A NE2 1 
ATOM   1565 N N   . HIS A 1 256 ? 160.871 144.798 133.151 1.00 92.58  ? 256 HIS A N   1 
ATOM   1566 C CA  . HIS A 1 256 ? 160.086 145.760 133.916 1.00 92.58  ? 256 HIS A CA  1 
ATOM   1567 C C   . HIS A 1 256 ? 159.156 145.080 134.912 1.00 92.58  ? 256 HIS A C   1 
ATOM   1568 O O   . HIS A 1 256 ? 159.011 145.566 136.040 1.00 92.58  ? 256 HIS A O   1 
ATOM   1569 C CB  . HIS A 1 256 ? 159.280 146.668 132.988 1.00 92.58  ? 256 HIS A CB  1 
ATOM   1570 C CG  . HIS A 1 256 ? 160.123 147.558 132.132 1.00 92.58  ? 256 HIS A CG  1 
ATOM   1571 N ND1 . HIS A 1 256 ? 160.314 147.331 130.788 1.00 92.58  ? 256 HIS A ND1 1 
ATOM   1572 C CD2 . HIS A 1 256 ? 160.838 148.665 132.431 1.00 92.58  ? 256 HIS A CD2 1 
ATOM   1573 C CE1 . HIS A 1 256 ? 161.099 148.270 130.292 1.00 92.58  ? 256 HIS A CE1 1 
ATOM   1574 N NE2 . HIS A 1 256 ? 161.431 149.092 131.270 1.00 92.58  ? 256 HIS A NE2 1 
ATOM   1575 N N   . ILE A 1 257 ? 158.542 143.962 134.532 1.00 87.32  ? 257 ILE A N   1 
ATOM   1576 C CA  . ILE A 1 257 ? 157.664 143.257 135.454 1.00 87.32  ? 257 ILE A CA  1 
ATOM   1577 C C   . ILE A 1 257 ? 158.427 142.774 136.678 1.00 87.32  ? 257 ILE A C   1 
ATOM   1578 O O   . ILE A 1 257 ? 157.970 142.960 137.812 1.00 87.32  ? 257 ILE A O   1 
ATOM   1579 C CB  . ILE A 1 257 ? 156.967 142.091 134.737 1.00 87.32  ? 257 ILE A CB  1 
ATOM   1580 C CG1 . ILE A 1 257 ? 155.986 142.620 133.691 1.00 87.32  ? 257 ILE A CG1 1 
ATOM   1581 C CG2 . ILE A 1 257 ? 156.257 141.199 135.731 1.00 87.32  ? 257 ILE A CG2 1 
ATOM   1582 C CD1 . ILE A 1 257 ? 154.951 143.574 134.242 1.00 87.32  ? 257 ILE A CD1 1 
ATOM   1583 N N   . VAL A 1 258 ? 159.597 142.166 136.493 1.00 84.76  ? 258 VAL A N   1 
ATOM   1584 C CA  . VAL A 1 258 ? 160.340 141.693 137.653 1.00 84.76  ? 258 VAL A CA  1 
ATOM   1585 C C   . VAL A 1 258 ? 160.924 142.840 138.469 1.00 84.76  ? 258 VAL A C   1 
ATOM   1586 O O   . VAL A 1 258 ? 161.034 142.718 139.696 1.00 84.76  ? 258 VAL A O   1 
ATOM   1587 C CB  . VAL A 1 258 ? 161.448 140.706 137.259 1.00 84.76  ? 258 VAL A CB  1 
ATOM   1588 C CG1 . VAL A 1 258 ? 162.585 141.414 136.550 1.00 84.76  ? 258 VAL A CG1 1 
ATOM   1589 C CG2 . VAL A 1 258 ? 161.940 139.960 138.486 1.00 84.76  ? 258 VAL A CG2 1 
ATOM   1590 N N   . THR A 1 259 ? 161.286 143.955 137.835 1.00 80.90  ? 259 THR A N   1 
ATOM   1591 C CA  . THR A 1 259 ? 161.734 145.110 138.600 1.00 80.90  ? 259 THR A CA  1 
ATOM   1592 C C   . THR A 1 259 ? 160.627 145.624 139.505 1.00 80.90  ? 259 THR A C   1 
ATOM   1593 O O   . THR A 1 259 ? 160.863 145.921 140.682 1.00 80.90  ? 259 THR A O   1 
ATOM   1594 C CB  . THR A 1 259 ? 162.212 146.214 137.662 1.00 80.90  ? 259 THR A CB  1 
ATOM   1595 O OG1 . THR A 1 259 ? 163.438 145.816 137.042 1.00 80.90  ? 259 THR A OG1 1 
ATOM   1596 C CG2 . THR A 1 259 ? 162.437 147.493 138.424 1.00 80.90  ? 259 THR A CG2 1 
ATOM   1597 N N   . LEU A 1 260 ? 159.407 145.732 138.982 1.00 74.81  ? 260 LEU A N   1 
ATOM   1598 C CA  . LEU A 1 260 ? 158.310 146.142 139.848 1.00 74.81  ? 260 LEU A CA  1 
ATOM   1599 C C   . LEU A 1 260 ? 158.002 145.121 140.924 1.00 74.81  ? 260 LEU A C   1 
ATOM   1600 O O   . LEU A 1 260 ? 157.652 145.511 142.038 1.00 74.81  ? 260 LEU A O   1 
ATOM   1601 C CB  . LEU A 1 260 ? 157.035 146.429 139.063 1.00 74.81  ? 260 LEU A CB  1 
ATOM   1602 C CG  . LEU A 1 260 ? 156.919 147.812 138.440 1.00 74.81  ? 260 LEU A CG  1 
ATOM   1603 C CD1 . LEU A 1 260 ? 156.893 148.840 139.545 1.00 74.81  ? 260 LEU A CD1 1 
ATOM   1604 C CD2 . LEU A 1 260 ? 158.023 148.095 137.476 1.00 74.81  ? 260 LEU A CD2 1 
ATOM   1605 N N   . LEU A 1 261 ? 158.106 143.830 140.627 1.00 73.60  ? 261 LEU A N   1 
ATOM   1606 C CA  . LEU A 1 261 ? 157.885 142.861 141.690 1.00 73.60  ? 261 LEU A CA  1 
ATOM   1607 C C   . LEU A 1 261 ? 158.912 143.024 142.799 1.00 73.60  ? 261 LEU A C   1 
ATOM   1608 O O   . LEU A 1 261 ? 158.552 143.016 143.978 1.00 73.60  ? 261 LEU A O   1 
ATOM   1609 C CB  . LEU A 1 261 ? 157.910 141.442 141.137 1.00 73.60  ? 261 LEU A CB  1 
ATOM   1610 C CG  . LEU A 1 261 ? 156.725 141.081 140.249 1.00 73.60  ? 261 LEU A CG  1 
ATOM   1611 C CD1 . LEU A 1 261 ? 156.817 139.637 139.834 1.00 73.60  ? 261 LEU A CD1 1 
ATOM   1612 C CD2 . LEU A 1 261 ? 155.425 141.350 140.961 1.00 73.60  ? 261 LEU A CD2 1 
ATOM   1613 N N   . LEU A 1 262 ? 160.184 143.211 142.446 1.00 72.63  ? 262 LEU A N   1 
ATOM   1614 C CA  . LEU A 1 262 ? 161.185 143.503 143.466 1.00 72.63  ? 262 LEU A CA  1 
ATOM   1615 C C   . LEU A 1 262 ? 160.800 144.723 144.284 1.00 72.63  ? 262 LEU A C   1 
ATOM   1616 O O   . LEU A 1 262 ? 160.723 144.650 145.515 1.00 72.63  ? 262 LEU A O   1 
ATOM   1617 C CB  . LEU A 1 262 ? 162.549 143.743 142.831 1.00 72.63  ? 262 LEU A CB  1 
ATOM   1618 C CG  . LEU A 1 262 ? 163.312 142.660 142.086 1.00 72.63  ? 262 LEU A CG  1 
ATOM   1619 C CD1 . LEU A 1 262 ? 164.780 143.026 142.062 1.00 72.63  ? 262 LEU A CD1 1 
ATOM   1620 C CD2 . LEU A 1 262 ? 163.133 141.353 142.770 1.00 72.63  ? 262 LEU A CD2 1 
ATOM   1621 N N   . ILE A 1 263 ? 160.527 145.844 143.617 1.00 65.77  ? 263 ILE A N   1 
ATOM   1622 C CA  . ILE A 1 263 ? 160.308 147.092 144.341 1.00 65.77  ? 263 ILE A CA  1 
ATOM   1623 C C   . ILE A 1 263 ? 159.120 146.960 145.276 1.00 65.77  ? 263 ILE A C   1 
ATOM   1624 O O   . ILE A 1 263 ? 159.212 147.244 146.475 1.00 65.77  ? 263 ILE A O   1 
ATOM   1625 C CB  . ILE A 1 263 ? 160.098 148.258 143.364 1.00 65.77  ? 263 ILE A CB  1 
ATOM   1626 C CG1 . ILE A 1 263 ? 161.361 148.558 142.574 1.00 65.77  ? 263 ILE A CG1 1 
ATOM   1627 C CG2 . ILE A 1 263 ? 159.698 149.478 144.120 1.00 65.77  ? 263 ILE A CG2 1 
ATOM   1628 C CD1 . ILE A 1 263 ? 161.241 149.770 141.720 1.00 65.77  ? 263 ILE A CD1 1 
ATOM   1629 N N   . TRP A 1 264 ? 157.996 146.494 144.746 1.00 66.55  ? 264 TRP A N   1 
ATOM   1630 C CA  . TRP A 1 264 ? 156.774 146.451 145.528 1.00 66.55  ? 264 TRP A CA  1 
ATOM   1631 C C   . TRP A 1 264 ? 156.858 145.422 146.644 1.00 66.55  ? 264 TRP A C   1 
ATOM   1632 O O   . TRP A 1 264 ? 156.531 145.723 147.795 1.00 66.55  ? 264 TRP A O   1 
ATOM   1633 C CB  . TRP A 1 264 ? 155.597 146.155 144.609 1.00 66.55  ? 264 TRP A CB  1 
ATOM   1634 C CG  . TRP A 1 264 ? 154.420 145.642 145.312 1.00 66.55  ? 264 TRP A CG  1 
ATOM   1635 C CD1 . TRP A 1 264 ? 153.601 146.337 146.135 1.00 66.55  ? 264 TRP A CD1 1 
ATOM   1636 C CD2 . TRP A 1 264 ? 153.910 144.314 145.261 1.00 66.55  ? 264 TRP A CD2 1 
ATOM   1637 N NE1 . TRP A 1 264 ? 152.607 145.526 146.605 1.00 66.55  ? 264 TRP A NE1 1 
ATOM   1638 C CE2 . TRP A 1 264 ? 152.778 144.274 146.080 1.00 66.55  ? 264 TRP A CE2 1 
ATOM   1639 C CE3 . TRP A 1 264 ? 154.305 143.154 144.602 1.00 66.55  ? 264 TRP A CE3 1 
ATOM   1640 C CZ2 . TRP A 1 264 ? 152.037 143.125 146.261 1.00 66.55  ? 264 TRP A CZ2 1 
ATOM   1641 C CZ3 . TRP A 1 264 ? 153.569 142.017 144.782 1.00 66.55  ? 264 TRP A CZ3 1 
ATOM   1642 C CH2 . TRP A 1 264 ? 152.448 142.007 145.603 1.00 66.55  ? 264 TRP A CH2 1 
ATOM   1643 N N   . SER A 1 265 ? 157.292 144.203 146.335 1.00 64.63  ? 265 SER A N   1 
ATOM   1644 C CA  . SER A 1 265 ? 157.308 143.169 147.349 1.00 64.63  ? 265 SER A CA  1 
ATOM   1645 C C   . SER A 1 265 ? 158.402 143.374 148.376 1.00 64.63  ? 265 SER A C   1 
ATOM   1646 O O   . SER A 1 265 ? 158.377 142.716 149.416 1.00 64.63  ? 265 SER A O   1 
ATOM   1647 C CB  . SER A 1 265 ? 157.474 141.803 146.699 1.00 64.63  ? 265 SER A CB  1 
ATOM   1648 O OG  . SER A 1 265 ? 158.477 141.839 145.705 1.00 64.63  ? 265 SER A OG  1 
ATOM   1649 N N   . SER A 1 266 ? 159.365 144.255 148.121 1.00 63.06  ? 266 SER A N   1 
ATOM   1650 C CA  . SER A 1 266 ? 160.331 144.539 149.167 1.00 63.06  ? 266 SER A CA  1 
ATOM   1651 C C   . SER A 1 266 ? 159.948 145.759 149.985 1.00 63.06  ? 266 SER A C   1 
ATOM   1652 O O   . SER A 1 266 ? 160.321 145.848 151.155 1.00 63.06  ? 266 SER A O   1 
ATOM   1653 C CB  . SER A 1 266 ? 161.716 144.719 148.566 1.00 63.06  ? 266 SER A CB  1 
ATOM   1654 O OG  . SER A 1 266 ? 161.758 145.857 147.744 1.00 63.06  ? 266 SER A OG  1 
ATOM   1655 N N   . TYR A 1 267 ? 159.217 146.708 149.408 1.00 58.93  ? 267 TYR A N   1 
ATOM   1656 C CA  . TYR A 1 267 ? 158.713 147.809 150.213 1.00 58.93  ? 267 TYR A CA  1 
ATOM   1657 C C   . TYR A 1 267 ? 157.558 147.394 151.103 1.00 58.93  ? 267 TYR A C   1 
ATOM   1658 O O   . TYR A 1 267 ? 157.511 147.797 152.266 1.00 58.93  ? 267 TYR A O   1 
ATOM   1659 C CB  . TYR A 1 267 ? 158.268 148.950 149.316 1.00 58.93  ? 267 TYR A CB  1 
ATOM   1660 C CG  . TYR A 1 267 ? 157.899 150.205 150.047 1.00 58.93  ? 267 TYR A CG  1 
ATOM   1661 C CD1 . TYR A 1 267 ? 156.581 150.567 150.207 1.00 58.93  ? 267 TYR A CD1 1 
ATOM   1662 C CD2 . TYR A 1 267 ? 158.868 151.028 150.571 1.00 58.93  ? 267 TYR A CD2 1 
ATOM   1663 C CE1 . TYR A 1 267 ? 156.242 151.714 150.861 1.00 58.93  ? 267 TYR A CE1 1 
ATOM   1664 C CE2 . TYR A 1 267 ? 158.539 152.171 151.228 1.00 58.93  ? 267 TYR A CE2 1 
ATOM   1665 C CZ  . TYR A 1 267 ? 157.225 152.511 151.372 1.00 58.93  ? 267 TYR A CZ  1 
ATOM   1666 O OH  . TYR A 1 267 ? 156.894 153.662 152.035 1.00 58.93  ? 267 TYR A OH  1 
ATOM   1667 N N   . VAL A 1 268 ? 156.631 146.589 150.582 1.00 59.13  ? 268 VAL A N   1 
ATOM   1668 C CA  . VAL A 1 268 ? 155.485 146.129 151.351 1.00 59.13  ? 268 VAL A CA  1 
ATOM   1669 C C   . VAL A 1 268 ? 155.872 145.209 152.494 1.00 59.13  ? 268 VAL A C   1 
ATOM   1670 O O   . VAL A 1 268 ? 155.313 145.331 153.589 1.00 59.13  ? 268 VAL A O   1 
ATOM   1671 C CB  . VAL A 1 268 ? 154.494 145.438 150.397 1.00 59.13  ? 268 VAL A CB  1 
ATOM   1672 C CG1 . VAL A 1 268 ? 153.549 144.562 151.149 1.00 59.13  ? 268 VAL A CG1 1 
ATOM   1673 C CG2 . VAL A 1 268 ? 153.731 146.474 149.627 1.00 59.13  ? 268 VAL A CG2 1 
ATOM   1674 N N   . PHE A 1 269 ? 156.818 144.299 152.283 1.00 62.07  ? 269 PHE A N   1 
ATOM   1675 C CA  . PHE A 1 269 ? 157.184 143.326 153.299 1.00 62.07  ? 269 PHE A CA  1 
ATOM   1676 C C   . PHE A 1 269 ? 158.415 143.739 154.089 1.00 62.07  ? 269 PHE A C   1 
ATOM   1677 O O   . PHE A 1 269 ? 159.040 142.884 154.721 1.00 62.07  ? 269 PHE A O   1 
ATOM   1678 C CB  . PHE A 1 269 ? 157.408 141.955 152.670 1.00 62.07  ? 269 PHE A CB  1 
ATOM   1679 C CG  . PHE A 1 269 ? 156.143 141.246 152.322 1.00 62.07  ? 269 PHE A CG  1 
ATOM   1680 C CD1 . PHE A 1 269 ? 155.312 140.771 153.307 1.00 62.07  ? 269 PHE A CD1 1 
ATOM   1681 C CD2 . PHE A 1 269 ? 155.784 141.057 151.010 1.00 62.07  ? 269 PHE A CD2 1 
ATOM   1682 C CE1 . PHE A 1 269 ? 154.148 140.126 152.989 1.00 62.07  ? 269 PHE A CE1 1 
ATOM   1683 C CE2 . PHE A 1 269 ? 154.622 140.412 150.693 1.00 62.07  ? 269 PHE A CE2 1 
ATOM   1684 C CZ  . PHE A 1 269 ? 153.805 139.947 151.684 1.00 62.07  ? 269 PHE A CZ  1 
ATOM   1685 N N   . HIS A 1 270 ? 158.787 145.013 154.051 1.00 64.28  ? 270 HIS A N   1 
ATOM   1686 C CA  . HIS A 1 270 ? 159.794 145.619 154.912 1.00 64.28  ? 270 HIS A CA  1 
ATOM   1687 C C   . HIS A 1 270 ? 161.217 145.167 154.616 1.00 64.28  ? 270 HIS A C   1 
ATOM   1688 O O   . HIS A 1 270 ? 162.113 145.437 155.412 1.00 64.28  ? 270 HIS A O   1 
ATOM   1689 C CB  . HIS A 1 270 ? 159.487 145.362 156.383 1.00 64.28  ? 270 HIS A CB  1 
ATOM   1690 C CG  . HIS A 1 270 ? 158.044 145.515 156.736 1.00 64.28  ? 270 HIS A CG  1 
ATOM   1691 N ND1 . HIS A 1 270 ? 157.407 146.735 156.752 1.00 64.28  ? 270 HIS A ND1 1 
ATOM   1692 C CD2 . HIS A 1 270 ? 157.112 144.602 157.087 1.00 64.28  ? 270 HIS A CD2 1 
ATOM   1693 C CE1 . HIS A 1 270 ? 156.145 146.567 157.093 1.00 64.28  ? 270 HIS A CE1 1 
ATOM   1694 N NE2 . HIS A 1 270 ? 155.939 145.281 157.303 1.00 64.28  ? 270 HIS A NE2 1 
ATOM   1695 N N   . PHE A 1 271 ? 161.462 144.498 153.494 1.00 66.89  ? 271 PHE A N   1 
ATOM   1696 C CA  . PHE A 1 271 ? 162.807 144.059 153.135 1.00 66.89  ? 271 PHE A CA  1 
ATOM   1697 C C   . PHE A 1 271 ? 163.495 145.135 152.305 1.00 66.89  ? 271 PHE A C   1 
ATOM   1698 O O   . PHE A 1 271 ? 164.049 144.876 151.244 1.00 66.89  ? 271 PHE A O   1 
ATOM   1699 C CB  . PHE A 1 271 ? 162.750 142.762 152.348 1.00 66.89  ? 271 PHE A CB  1 
ATOM   1700 C CG  . PHE A 1 271 ? 162.546 141.549 153.174 1.00 66.89  ? 271 PHE A CG  1 
ATOM   1701 C CD1 . PHE A 1 271 ? 163.613 140.938 153.794 1.00 66.89  ? 271 PHE A CD1 1 
ATOM   1702 C CD2 . PHE A 1 271 ? 161.300 140.983 153.289 1.00 66.89  ? 271 PHE A CD2 1 
ATOM   1703 C CE1 . PHE A 1 271 ? 163.432 139.800 154.535 1.00 66.89  ? 271 PHE A CE1 1 
ATOM   1704 C CE2 . PHE A 1 271 ? 161.114 139.848 154.029 1.00 66.89  ? 271 PHE A CE2 1 
ATOM   1705 C CZ  . PHE A 1 271 ? 162.179 139.255 154.654 1.00 66.89  ? 271 PHE A CZ  1 
ATOM   1706 N N   . THR A 1 272 ? 163.471 146.358 152.809 1.00 66.41  ? 272 THR A N   1 
ATOM   1707 C CA  . THR A 1 272 ? 163.896 147.474 151.980 1.00 66.41  ? 272 THR A CA  1 
ATOM   1708 C C   . THR A 1 272 ? 165.394 147.747 152.049 1.00 66.41  ? 272 THR A C   1 
ATOM   1709 O O   . THR A 1 272 ? 165.999 148.083 151.021 1.00 66.41  ? 272 THR A O   1 
ATOM   1710 C CB  . THR A 1 272 ? 163.091 148.724 152.344 1.00 66.41  ? 272 THR A CB  1 
ATOM   1711 O OG1 . THR A 1 272 ? 163.384 149.767 151.417 1.00 66.41  ? 272 THR A OG1 1 
ATOM   1712 C CG2 . THR A 1 272 ? 163.382 149.183 153.749 1.00 66.41  ? 272 THR A CG2 1 
ATOM   1713 N N   . LYS A 1 273 ? 166.025 147.560 153.210 1.00 73.50  ? 273 LYS A N   1 
ATOM   1714 C CA  . LYS A 1 273 ? 167.478 147.644 153.256 1.00 73.50  ? 273 LYS A CA  1 
ATOM   1715 C C   . LYS A 1 273 ? 168.110 146.610 152.346 1.00 73.50  ? 273 LYS A C   1 
ATOM   1716 O O   . LYS A 1 273 ? 169.077 146.904 151.642 1.00 73.50  ? 273 LYS A O   1 
ATOM   1717 C CB  . LYS A 1 273 ? 168.001 147.469 154.677 1.00 73.50  ? 273 LYS A CB  1 
ATOM   1718 C CG  . LYS A 1 273 ? 167.657 148.573 155.637 1.00 73.50  ? 273 LYS A CG  1 
ATOM   1719 C CD  . LYS A 1 273 ? 168.289 148.296 156.985 1.00 73.50  ? 273 LYS A CD  1 
ATOM   1720 C CE  . LYS A 1 273 ? 167.910 149.341 158.013 1.00 73.50  ? 273 LYS A CE  1 
ATOM   1721 N NZ  . LYS A 1 273 ? 168.498 150.661 157.683 1.00 73.50  ? 273 LYS A NZ  1 
ATOM   1722 N N   . MET A 1 274 ? 167.578 145.392 152.337 1.00 77.55  ? 274 MET A N   1 
ATOM   1723 C CA  . MET A 1 274 ? 168.161 144.355 151.497 1.00 77.55  ? 274 MET A CA  1 
ATOM   1724 C C   . MET A 1 274 ? 167.816 144.591 150.033 1.00 77.55  ? 274 MET A C   1 
ATOM   1725 O O   . MET A 1 274 ? 168.413 143.990 149.136 1.00 77.55  ? 274 MET A O   1 
ATOM   1726 C CB  . MET A 1 274 ? 167.702 142.982 151.991 1.00 77.55  ? 274 MET A CB  1 
ATOM   1727 C CG  . MET A 1 274 ? 168.062 141.800 151.127 1.00 77.55  ? 274 MET A CG  1 
ATOM   1728 S SD  . MET A 1 274 ? 166.825 140.507 151.176 1.00 77.55  ? 274 MET A SD  1 
ATOM   1729 C CE  . MET A 1 274 ? 165.647 141.169 150.030 1.00 77.55  ? 274 MET A CE  1 
ATOM   1730 N N   . GLY A 1 275 ? 166.876 145.496 149.770 1.00 73.42  ? 275 GLY A N   1 
ATOM   1731 C CA  . GLY A 1 275 ? 166.556 145.835 148.397 1.00 73.42  ? 275 GLY A CA  1 
ATOM   1732 C C   . GLY A 1 275 ? 167.370 146.986 147.844 1.00 73.42  ? 275 GLY A C   1 
ATOM   1733 O O   . GLY A 1 275 ? 167.453 147.154 146.627 1.00 73.42  ? 275 GLY A O   1 
ATOM   1734 N N   . LEU A 1 276 ? 167.958 147.805 148.710 1.00 74.84  ? 276 LEU A N   1 
ATOM   1735 C CA  . LEU A 1 276 ? 168.787 148.910 148.221 1.00 74.84  ? 276 LEU A CA  1 
ATOM   1736 C C   . LEU A 1 276 ? 170.008 148.478 147.409 1.00 74.84  ? 276 LEU A C   1 
ATOM   1737 O O   . LEU A 1 276 ? 170.203 149.008 146.300 1.00 74.84  ? 276 LEU A O   1 
ATOM   1738 C CB  . LEU A 1 276 ? 169.220 149.782 149.403 1.00 74.84  ? 276 LEU A CB  1 
ATOM   1739 C CG  . LEU A 1 276 ? 169.943 151.062 149.015 1.00 74.84  ? 276 LEU A CG  1 
ATOM   1740 C CD1 . LEU A 1 276 ? 168.976 152.027 148.394 1.00 74.84  ? 276 LEU A CD1 1 
ATOM   1741 C CD2 . LEU A 1 276 ? 170.605 151.680 150.222 1.00 74.84  ? 276 LEU A CD2 1 
ATOM   1742 N N   . PRO A 1 277 ? 170.867 147.564 147.879 1.00 77.16  ? 277 PRO A N   1 
ATOM   1743 C CA  . PRO A 1 277 ? 172.053 147.219 147.086 1.00 77.16  ? 277 PRO A CA  1 
ATOM   1744 C C   . PRO A 1 277 ? 171.732 146.678 145.712 1.00 77.16  ? 277 PRO A C   1 
ATOM   1745 O O   . PRO A 1 277 ? 172.483 146.916 144.762 1.00 77.16  ? 277 PRO A O   1 
ATOM   1746 C CB  . PRO A 1 277 ? 172.742 146.163 147.953 1.00 77.16  ? 277 PRO A CB  1 
ATOM   1747 C CG  . PRO A 1 277 ? 172.320 146.481 149.303 1.00 77.16  ? 277 PRO A CG  1 
ATOM   1748 C CD  . PRO A 1 277 ? 170.892 146.867 149.170 1.00 77.16  ? 277 PRO A CD  1 
ATOM   1749 N N   . ILE A 1 278 ? 170.638 145.937 145.581 1.00 73.88  ? 278 ILE A N   1 
ATOM   1750 C CA  . ILE A 1 278 ? 170.280 145.405 144.276 1.00 73.88  ? 278 ILE A CA  1 
ATOM   1751 C C   . ILE A 1 278 ? 169.977 146.539 143.308 1.00 73.88  ? 278 ILE A C   1 
ATOM   1752 O O   . ILE A 1 278 ? 170.397 146.507 142.146 1.00 73.88  ? 278 ILE A O   1 
ATOM   1753 C CB  . ILE A 1 278 ? 169.116 144.416 144.416 1.00 73.88  ? 278 ILE A CB  1 
ATOM   1754 C CG1 . ILE A 1 278 ? 169.574 143.240 145.270 1.00 73.88  ? 278 ILE A CG1 1 
ATOM   1755 C CG2 . ILE A 1 278 ? 168.674 143.929 143.069 1.00 73.88  ? 278 ILE A CG2 1 
ATOM   1756 C CD1 . ILE A 1 278 ? 168.470 142.365 145.744 1.00 73.88  ? 278 ILE A CD1 1 
ATOM   1757 N N   . TYR A 1 279 ? 169.280 147.577 143.776 1.00 76.34  ? 279 TYR A N   1 
ATOM   1758 C CA  . TYR A 1 279 ? 169.069 148.747 142.931 1.00 76.34  ? 279 TYR A CA  1 
ATOM   1759 C C   . TYR A 1 279 ? 170.394 149.355 142.531 1.00 76.34  ? 279 TYR A C   1 
ATOM   1760 O O   . TYR A 1 279 ? 170.577 149.774 141.384 1.00 76.34  ? 279 TYR A O   1 
ATOM   1761 C CB  . TYR A 1 279 ? 168.282 149.823 143.658 1.00 76.34  ? 279 TYR A CB  1 
ATOM   1762 C CG  . TYR A 1 279 ? 166.865 149.506 143.976 1.00 76.34  ? 279 TYR A CG  1 
ATOM   1763 C CD1 . TYR A 1 279 ? 166.208 148.445 143.386 1.00 76.34  ? 279 TYR A CD1 1 
ATOM   1764 C CD2 . TYR A 1 279 ? 166.183 150.278 144.893 1.00 76.34  ? 279 TYR A CD2 1 
ATOM   1765 C CE1 . TYR A 1 279 ? 164.901 148.166 143.714 1.00 76.34  ? 279 TYR A CE1 1 
ATOM   1766 C CE2 . TYR A 1 279 ? 164.900 150.019 145.216 1.00 76.34  ? 279 TYR A CE2 1 
ATOM   1767 C CZ  . TYR A 1 279 ? 164.258 148.969 144.634 1.00 76.34  ? 279 TYR A CZ  1 
ATOM   1768 O OH  . TYR A 1 279 ? 162.960 148.742 145.001 1.00 76.34  ? 279 TYR A OH  1 
ATOM   1769 N N   . ILE A 1 280 ? 171.318 149.456 143.484 1.00 79.55  ? 280 ILE A N   1 
ATOM   1770 C CA  . ILE A 1 280 ? 172.596 150.097 143.194 1.00 79.55  ? 280 ILE A CA  1 
ATOM   1771 C C   . ILE A 1 280 ? 173.333 149.341 142.098 1.00 79.55  ? 280 ILE A C   1 
ATOM   1772 O O   . ILE A 1 280 ? 173.842 149.937 141.138 1.00 79.55  ? 280 ILE A O   1 
ATOM   1773 C CB  . ILE A 1 280 ? 173.436 150.200 144.474 1.00 79.55  ? 280 ILE A CB  1 
ATOM   1774 C CG1 . ILE A 1 280 ? 172.879 151.307 145.358 1.00 79.55  ? 280 ILE A CG1 1 
ATOM   1775 C CG2 . ILE A 1 280 ? 174.889 150.436 144.141 1.00 79.55  ? 280 ILE A CG2 1 
ATOM   1776 C CD1 . ILE A 1 280 ? 173.502 151.357 146.701 1.00 79.55  ? 280 ILE A CD1 1 
ATOM   1777 N N   . THR A 1 281 ? 173.399 148.018 142.223 1.00 81.57  ? 281 THR A N   1 
ATOM   1778 C CA  . THR A 1 281 ? 174.097 147.222 141.221 1.00 81.57  ? 281 THR A CA  1 
ATOM   1779 C C   . THR A 1 281 ? 173.433 147.363 139.861 1.00 81.57  ? 281 THR A C   1 
ATOM   1780 O O   . THR A 1 281 ? 174.104 147.596 138.845 1.00 81.57  ? 281 THR A O   1 
ATOM   1781 C CB  . THR A 1 281 ? 174.143 145.757 141.639 1.00 81.57  ? 281 THR A CB  1 
ATOM   1782 O OG1 . THR A 1 281 ? 172.822 145.215 141.622 1.00 81.57  ? 281 THR A OG1 1 
ATOM   1783 C CG2 . THR A 1 281 ? 174.728 145.618 143.025 1.00 81.57  ? 281 THR A CG2 1 
ATOM   1784 N N   . MET A 1 282 ? 172.103 147.252 139.824 1.00 86.06  ? 282 MET A N   1 
ATOM   1785 C CA  . MET A 1 282 ? 171.404 147.335 138.550 1.00 86.06  ? 282 MET A CA  1 
ATOM   1786 C C   . MET A 1 282 ? 171.648 148.682 137.886 1.00 86.06  ? 282 MET A C   1 
ATOM   1787 O O   . MET A 1 282 ? 171.947 148.745 136.689 1.00 86.06  ? 282 MET A O   1 
ATOM   1788 C CB  . MET A 1 282 ? 169.912 147.103 138.756 1.00 86.06  ? 282 MET A CB  1 
ATOM   1789 C CG  . MET A 1 282 ? 169.583 145.714 139.250 1.00 86.06  ? 282 MET A CG  1 
ATOM   1790 S SD  . MET A 1 282 ? 170.017 144.423 138.093 1.00 86.06  ? 282 MET A SD  1 
ATOM   1791 C CE  . MET A 1 282 ? 169.717 142.978 139.095 1.00 86.06  ? 282 MET A CE  1 
ATOM   1792 N N   . ASP A 1 283 ? 171.561 149.769 138.655 1.00 87.41  ? 283 ASP A N   1 
ATOM   1793 C CA  . ASP A 1 283 ? 171.782 151.088 138.080 1.00 87.41  ? 283 ASP A CA  1 
ATOM   1794 C C   . ASP A 1 283 ? 173.197 151.255 137.554 1.00 87.41  ? 283 ASP A C   1 
ATOM   1795 O O   . ASP A 1 283 ? 173.374 151.626 136.392 1.00 87.41  ? 283 ASP A O   1 
ATOM   1796 C CB  . ASP A 1 283 ? 171.480 152.180 139.099 1.00 87.41  ? 283 ASP A CB  1 
ATOM   1797 C CG  . ASP A 1 283 ? 169.997 152.395 139.301 1.00 87.41  ? 283 ASP A CG  1 
ATOM   1798 O OD1 . ASP A 1 283 ? 169.208 151.933 138.455 1.00 87.41  ? 283 ASP A OD1 1 
ATOM   1799 O OD2 . ASP A 1 283 ? 169.621 153.054 140.293 1.00 87.41  ? 283 ASP A OD2 1 
ATOM   1800 N N   . VAL A 1 284 ? 174.217 150.976 138.363 1.00 86.29  ? 284 VAL A N   1 
ATOM   1801 C CA  . VAL A 1 284 ? 175.573 151.235 137.883 1.00 86.29  ? 284 VAL A CA  1 
ATOM   1802 C C   . VAL A 1 284 ? 175.883 150.396 136.646 1.00 86.29  ? 284 VAL A C   1 
ATOM   1803 O O   . VAL A 1 284 ? 176.489 150.888 135.677 1.00 86.29  ? 284 VAL A O   1 
ATOM   1804 C CB  . VAL A 1 284 ? 176.597 150.997 139.003 1.00 86.29  ? 284 VAL A CB  1 
ATOM   1805 C CG1 . VAL A 1 284 ? 177.977 151.384 138.527 1.00 86.29  ? 284 VAL A CG1 1 
ATOM   1806 C CG2 . VAL A 1 284 ? 176.229 151.799 140.221 1.00 86.29  ? 284 VAL A CG2 1 
ATOM   1807 N N   . SER A 1 285 ? 175.452 149.132 136.643 1.00 91.23  ? 285 SER A N   1 
ATOM   1808 C CA  . SER A 1 285 ? 175.645 148.312 135.456 1.00 91.23  ? 285 SER A CA  1 
ATOM   1809 C C   . SER A 1 285 ? 174.939 148.918 134.253 1.00 91.23  ? 285 SER A C   1 
ATOM   1810 O O   . SER A 1 285 ? 175.501 148.960 133.151 1.00 91.23  ? 285 SER A O   1 
ATOM   1811 C CB  . SER A 1 285 ? 175.139 146.897 135.707 1.00 91.23  ? 285 SER A CB  1 
ATOM   1812 O OG  . SER A 1 285 ? 173.739 146.900 135.898 1.00 91.23  ? 285 SER A OG  1 
ATOM   1813 N N   . ASP A 1 286 ? 173.713 149.408 134.439 1.00 93.68  ? 286 ASP A N   1 
ATOM   1814 C CA  . ASP A 1 286 ? 172.998 149.996 133.316 1.00 93.68  ? 286 ASP A CA  1 
ATOM   1815 C C   . ASP A 1 286 ? 173.619 151.307 132.865 1.00 93.68  ? 286 ASP A C   1 
ATOM   1816 O O   . ASP A 1 286 ? 173.589 151.618 131.674 1.00 93.68  ? 286 ASP A O   1 
ATOM   1817 C CB  . ASP A 1 286 ? 171.530 150.191 133.673 1.00 93.68  ? 286 ASP A CB  1 
ATOM   1818 C CG  . ASP A 1 286 ? 170.791 148.883 133.777 1.00 93.68  ? 286 ASP A CG  1 
ATOM   1819 O OD1 . ASP A 1 286 ? 171.466 147.835 133.839 1.00 93.68  ? 286 ASP A OD1 1 
ATOM   1820 O OD2 . ASP A 1 286 ? 169.543 148.895 133.790 1.00 93.68  ? 286 ASP A OD2 1 
ATOM   1821 N N   . PHE A 1 287 ? 174.182 152.089 133.783 1.00 90.12  ? 287 PHE A N   1 
ATOM   1822 C CA  . PHE A 1 287 ? 174.874 153.303 133.362 1.00 90.12  ? 287 PHE A CA  1 
ATOM   1823 C C   . PHE A 1 287 ? 176.050 152.992 132.456 1.00 90.12  ? 287 PHE A C   1 
ATOM   1824 O O   . PHE A 1 287 ? 176.211 153.624 131.405 1.00 90.12  ? 287 PHE A O   1 
ATOM   1825 C CB  . PHE A 1 287 ? 175.358 154.081 134.576 1.00 90.12  ? 287 PHE A CB  1 
ATOM   1826 C CG  . PHE A 1 287 ? 176.267 155.216 134.243 1.00 90.12  ? 287 PHE A CG  1 
ATOM   1827 C CD1 . PHE A 1 287 ? 175.762 156.406 133.777 1.00 90.12  ? 287 PHE A CD1 1 
ATOM   1828 C CD2 . PHE A 1 287 ? 177.630 155.095 134.412 1.00 90.12  ? 287 PHE A CD2 1 
ATOM   1829 C CE1 . PHE A 1 287 ? 176.599 157.452 133.479 1.00 90.12  ? 287 PHE A CE1 1 
ATOM   1830 C CE2 . PHE A 1 287 ? 178.470 156.135 134.116 1.00 90.12  ? 287 PHE A CE2 1 
ATOM   1831 C CZ  . PHE A 1 287 ? 177.955 157.316 133.646 1.00 90.12  ? 287 PHE A CZ  1 
ATOM   1832 N N   . LEU A 1 288 ? 176.875 152.019 132.837 1.00 94.81  ? 288 LEU A N   1 
ATOM   1833 C CA  . LEU A 1 288 ? 178.011 151.677 131.986 1.00 94.81  ? 288 LEU A CA  1 
ATOM   1834 C C   . LEU A 1 288 ? 177.556 151.050 130.672 1.00 94.81  ? 288 LEU A C   1 
ATOM   1835 O O   . LEU A 1 288 ? 178.129 151.329 129.609 1.00 94.81  ? 288 LEU A O   1 
ATOM   1836 C CB  . LEU A 1 288 ? 178.963 150.760 132.741 1.00 94.81  ? 288 LEU A CB  1 
ATOM   1837 C CG  . LEU A 1 288 ? 179.599 151.538 133.888 1.00 94.81  ? 288 LEU A CG  1 
ATOM   1838 C CD1 . LEU A 1 288 ? 180.053 150.619 134.996 1.00 94.81  ? 288 LEU A CD1 1 
ATOM   1839 C CD2 . LEU A 1 288 ? 180.746 152.379 133.364 1.00 94.81  ? 288 LEU A CD2 1 
ATOM   1840 N N   . LEU A 1 289 ? 176.511 150.223 130.720 1.00 99.23  ? 289 LEU A N   1 
ATOM   1841 C CA  . LEU A 1 289 ? 175.970 149.644 129.497 1.00 99.23  ? 289 LEU A CA  1 
ATOM   1842 C C   . LEU A 1 289 ? 175.463 150.718 128.546 1.00 99.23  ? 289 LEU A C   1 
ATOM   1843 O O   . LEU A 1 289 ? 175.694 150.640 127.337 1.00 99.23  ? 289 LEU A O   1 
ATOM   1844 C CB  . LEU A 1 289 ? 174.844 148.674 129.834 1.00 99.23  ? 289 LEU A CB  1 
ATOM   1845 C CG  . LEU A 1 289 ? 174.096 148.142 128.617 1.00 99.23  ? 289 LEU A CG  1 
ATOM   1846 C CD1 . LEU A 1 289 ? 175.028 147.321 127.748 1.00 99.23  ? 289 LEU A CD1 1 
ATOM   1847 C CD2 . LEU A 1 289 ? 172.888 147.330 129.038 1.00 99.23  ? 289 LEU A CD2 1 
ATOM   1848 N N   . SER A 1 290 ? 174.757 151.720 129.070 1.00 101.61 ? 290 SER A N   1 
ATOM   1849 C CA  . SER A 1 290 ? 174.234 152.786 128.229 1.00 101.61 ? 290 SER A CA  1 
ATOM   1850 C C   . SER A 1 290 ? 175.342 153.648 127.652 1.00 101.61 ? 290 SER A C   1 
ATOM   1851 O O   . SER A 1 290 ? 175.279 154.025 126.477 1.00 101.61 ? 290 SER A O   1 
ATOM   1852 C CB  . SER A 1 290 ? 173.262 153.648 129.024 1.00 101.61 ? 290 SER A CB  1 
ATOM   1853 O OG  . SER A 1 290 ? 172.266 152.844 129.626 1.00 101.61 ? 290 SER A OG  1 
ATOM   1854 N N   . PHE A 1 291 ? 176.362 153.958 128.447 1.00 105.98 ? 291 PHE A N   1 
ATOM   1855 C CA  . PHE A 1 291 ? 177.510 154.678 127.909 1.00 105.98 ? 291 PHE A CA  1 
ATOM   1856 C C   . PHE A 1 291 ? 178.131 153.923 126.741 1.00 105.98 ? 291 PHE A C   1 
ATOM   1857 O O   . PHE A 1 291 ? 178.353 154.493 125.663 1.00 105.98 ? 291 PHE A O   1 
ATOM   1858 C CB  . PHE A 1 291 ? 178.537 154.897 129.014 1.00 105.98 ? 291 PHE A CB  1 
ATOM   1859 C CG  . PHE A 1 291 ? 179.391 156.095 128.811 1.00 105.98 ? 291 PHE A CG  1 
ATOM   1860 C CD1 . PHE A 1 291 ? 178.826 157.330 128.607 1.00 105.98 ? 291 PHE A CD1 1 
ATOM   1861 C CD2 . PHE A 1 291 ? 180.763 155.987 128.838 1.00 105.98 ? 291 PHE A CD2 1 
ATOM   1862 C CE1 . PHE A 1 291 ? 179.608 158.440 128.423 1.00 105.98 ? 291 PHE A CE1 1 
ATOM   1863 C CE2 . PHE A 1 291 ? 181.555 157.090 128.655 1.00 105.98 ? 291 PHE A CE2 1 
ATOM   1864 C CZ  . PHE A 1 291 ? 180.976 158.319 128.447 1.00 105.98 ? 291 PHE A CZ  1 
ATOM   1865 N N   . SER A 1 292 ? 178.391 152.629 126.925 1.00 110.21 ? 292 SER A N   1 
ATOM   1866 C CA  . SER A 1 292 ? 179.008 151.859 125.855 1.00 110.21 ? 292 SER A CA  1 
ATOM   1867 C C   . SER A 1 292 ? 178.103 151.705 124.637 1.00 110.21 ? 292 SER A C   1 
ATOM   1868 O O   . SER A 1 292 ? 178.591 151.798 123.510 1.00 110.21 ? 292 SER A O   1 
ATOM   1869 C CB  . SER A 1 292 ? 179.432 150.494 126.379 1.00 110.21 ? 292 SER A CB  1 
ATOM   1870 O OG  . SER A 1 292 ? 180.290 150.654 127.492 1.00 110.21 ? 292 SER A OG  1 
ATOM   1871 N N   . LYS A 1 293 ? 176.802 151.487 124.823 1.00 112.43 ? 293 LYS A N   1 
ATOM   1872 C CA  . LYS A 1 293 ? 175.931 151.327 123.664 1.00 112.43 ? 293 LYS A CA  1 
ATOM   1873 C C   . LYS A 1 293 ? 175.798 152.627 122.891 1.00 112.43 ? 293 LYS A C   1 
ATOM   1874 O O   . LYS A 1 293 ? 175.714 152.610 121.658 1.00 112.43 ? 293 LYS A O   1 
ATOM   1875 C CB  . LYS A 1 293 ? 174.554 150.822 124.083 1.00 112.43 ? 293 LYS A CB  1 
ATOM   1876 C CG  . LYS A 1 293 ? 174.553 149.406 124.597 1.00 112.43 ? 293 LYS A CG  1 
ATOM   1877 C CD  . LYS A 1 293 ? 173.169 148.997 125.059 1.00 112.43 ? 293 LYS A CD  1 
ATOM   1878 C CE  . LYS A 1 293 ? 172.217 148.822 123.894 1.00 112.43 ? 293 LYS A CE  1 
ATOM   1879 N NZ  . LYS A 1 293 ? 172.600 147.650 123.060 1.00 112.43 ? 293 LYS A NZ  1 
ATOM   1880 N N   . THR A 1 294 ? 175.760 153.768 123.583 1.00 113.59 ? 294 THR A N   1 
ATOM   1881 C CA  . THR A 1 294 ? 175.637 155.016 122.841 1.00 113.59 ? 294 THR A CA  1 
ATOM   1882 C C   . THR A 1 294 ? 176.943 155.380 122.152 1.00 113.59 ? 294 THR A C   1 
ATOM   1883 O O   . THR A 1 294 ? 176.922 155.988 121.075 1.00 113.59 ? 294 THR A O   1 
ATOM   1884 C CB  . THR A 1 294 ? 175.168 156.149 123.746 1.00 113.59 ? 294 THR A CB  1 
ATOM   1885 O OG1 . THR A 1 294 ? 174.884 157.289 122.937 1.00 113.59 ? 294 THR A OG1 1 
ATOM   1886 C CG2 . THR A 1 294 ? 176.228 156.525 124.741 1.00 113.59 ? 294 THR A CG2 1 
ATOM   1887 N N   . LEU A 1 295 ? 178.087 154.997 122.728 1.00 115.02 ? 295 LEU A N   1 
ATOM   1888 C CA  . LEU A 1 295 ? 179.336 155.144 121.989 1.00 115.02 ? 295 LEU A CA  1 
ATOM   1889 C C   . LEU A 1 295 ? 179.420 154.157 120.835 1.00 115.02 ? 295 LEU A C   1 
ATOM   1890 O O   . LEU A 1 295 ? 180.155 154.392 119.875 1.00 115.02 ? 295 LEU A O   1 
ATOM   1891 C CB  . LEU A 1 295 ? 180.532 154.986 122.920 1.00 115.02 ? 295 LEU A CB  1 
ATOM   1892 C CG  . LEU A 1 295 ? 181.088 156.309 123.437 1.00 115.02 ? 295 LEU A CG  1 
ATOM   1893 C CD1 . LEU A 1 295 ? 181.695 157.074 122.288 1.00 115.02 ? 295 LEU A CD1 1 
ATOM   1894 C CD2 . LEU A 1 295 ? 180.009 157.139 124.094 1.00 115.02 ? 295 LEU A CD2 1 
ATOM   1895 N N   . ASN A 1 296 ? 178.706 153.036 120.921 1.00 117.61 ? 296 ASN A N   1 
ATOM   1896 C CA  . ASN A 1 296 ? 178.605 152.118 119.795 1.00 117.61 ? 296 ASN A CA  1 
ATOM   1897 C C   . ASN A 1 296 ? 177.780 152.676 118.648 1.00 117.61 ? 296 ASN A C   1 
ATOM   1898 O O   . ASN A 1 296 ? 178.238 152.655 117.502 1.00 117.61 ? 296 ASN A O   1 
ATOM   1899 C CB  . ASN A 1 296 ? 177.992 150.796 120.248 1.00 117.61 ? 296 ASN A CB  1 
ATOM   1900 C CG  . ASN A 1 296 ? 177.986 149.754 119.156 1.00 117.61 ? 296 ASN A CG  1 
ATOM   1901 O OD1 . ASN A 1 296 ? 176.940 149.208 118.811 1.00 117.61 ? 296 ASN A OD1 1 
ATOM   1902 N ND2 . ASN A 1 296 ? 179.156 149.467 118.605 1.00 117.61 ? 296 ASN A ND2 1 
ATOM   1903 N N   . TYR A 1 297 ? 176.580 153.180 118.928 1.00 122.73 ? 297 TYR A N   1 
ATOM   1904 C CA  . TYR A 1 297 ? 175.749 153.797 117.904 1.00 122.73 ? 297 TYR A CA  1 
ATOM   1905 C C   . TYR A 1 297 ? 176.219 155.202 117.557 1.00 122.73 ? 297 TYR A C   1 
ATOM   1906 O O   . TYR A 1 297 ? 175.598 155.870 116.723 1.00 122.73 ? 297 TYR A O   1 
ATOM   1907 C CB  . TYR A 1 297 ? 174.281 153.830 118.330 1.00 122.73 ? 297 TYR A CB  1 
ATOM   1908 C CG  . TYR A 1 297 ? 173.696 152.515 118.770 1.00 122.73 ? 297 TYR A CG  1 
ATOM   1909 C CD1 . TYR A 1 297 ? 173.140 152.374 120.031 1.00 122.73 ? 297 TYR A CD1 1 
ATOM   1910 C CD2 . TYR A 1 297 ? 173.680 151.417 117.922 1.00 122.73 ? 297 TYR A CD2 1 
ATOM   1911 C CE1 . TYR A 1 297 ? 172.594 151.177 120.442 1.00 122.73 ? 297 TYR A CE1 1 
ATOM   1912 C CE2 . TYR A 1 297 ? 173.135 150.212 118.326 1.00 122.73 ? 297 TYR A CE2 1 
ATOM   1913 C CZ  . TYR A 1 297 ? 172.594 150.101 119.588 1.00 122.73 ? 297 TYR A CZ  1 
ATOM   1914 O OH  . TYR A 1 297 ? 172.047 148.913 120.002 1.00 122.73 ? 297 TYR A OH  1 
ATOM   1915 N N   . LEU A 1 298 ? 177.289 155.665 118.196 1.00 123.50 ? 298 LEU A N   1 
ATOM   1916 C CA  . LEU A 1 298 ? 177.973 156.893 117.822 1.00 123.50 ? 298 LEU A CA  1 
ATOM   1917 C C   . LEU A 1 298 ? 179.456 156.558 117.723 1.00 123.50 ? 298 LEU A C   1 
ATOM   1918 O O   . LEU A 1 298 ? 180.303 157.254 118.289 1.00 123.50 ? 298 LEU A O   1 
ATOM   1919 C CB  . LEU A 1 298 ? 177.675 157.990 118.848 1.00 123.50 ? 298 LEU A CB  1 
ATOM   1920 C CG  . LEU A 1 298 ? 177.980 159.467 118.595 1.00 123.50 ? 298 LEU A CG  1 
ATOM   1921 C CD1 . LEU A 1 298 ? 176.852 160.290 119.177 1.00 123.50 ? 298 LEU A CD1 1 
ATOM   1922 C CD2 . LEU A 1 298 ? 179.285 159.895 119.242 1.00 123.50 ? 298 LEU A CD2 1 
ATOM   1923 N N   . ASP A 1 299 ? 179.767 155.472 117.009 1.00 125.92 ? 299 ASP A N   1 
ATOM   1924 C CA  . ASP A 1 299 ? 181.050 154.776 117.089 1.00 125.92 ? 299 ASP A CA  1 
ATOM   1925 C C   . ASP A 1 299 ? 182.289 155.666 117.091 1.00 125.92 ? 299 ASP A C   1 
ATOM   1926 O O   . ASP A 1 299 ? 182.330 156.716 116.442 1.00 125.92 ? 299 ASP A O   1 
ATOM   1927 C CB  . ASP A 1 299 ? 181.147 153.738 115.966 1.00 125.92 ? 299 ASP A CB  1 
ATOM   1928 C CG  . ASP A 1 299 ? 181.103 154.352 114.585 1.00 125.92 ? 299 ASP A CG  1 
ATOM   1929 O OD1 . ASP A 1 299 ? 180.952 155.585 114.465 1.00 125.92 ? 299 ASP A OD1 1 
ATOM   1930 O OD2 . ASP A 1 299 ? 181.226 153.588 113.606 1.00 125.92 ? 299 ASP A OD2 1 
ATOM   1931 N N   . SER A 1 300 ? 183.294 155.246 117.859 1.00 122.47 ? 300 SER A N   1 
ATOM   1932 C CA  . SER A 1 300 ? 184.574 155.935 117.950 1.00 122.47 ? 300 SER A CA  1 
ATOM   1933 C C   . SER A 1 300 ? 185.616 155.003 118.551 1.00 122.47 ? 300 SER A C   1 
ATOM   1934 O O   . SER A 1 300 ? 185.323 153.840 118.844 1.00 122.47 ? 300 SER A O   1 
ATOM   1935 C CB  . SER A 1 300 ? 184.447 157.204 118.792 1.00 122.47 ? 300 SER A CB  1 
ATOM   1936 O OG  . SER A 1 300 ? 184.263 156.887 120.158 1.00 122.47 ? 300 SER A OG  1 
ATOM   1937 N N   . GLY A 1 301 ? 186.831 155.503 118.747 1.00 123.52 ? 301 GLY A N   1 
ATOM   1938 C CA  . GLY A 1 301 ? 187.875 154.713 119.366 1.00 123.52 ? 301 GLY A CA  1 
ATOM   1939 C C   . GLY A 1 301 ? 187.561 154.359 120.803 1.00 123.52 ? 301 GLY A C   1 
ATOM   1940 O O   . GLY A 1 301 ? 187.983 153.313 121.302 1.00 123.52 ? 301 GLY A O   1 
ATOM   1941 N N   . LEU A 1 302 ? 186.827 155.237 121.481 1.00 122.92 ? 302 LEU A N   1 
ATOM   1942 C CA  . LEU A 1 302 ? 186.507 155.065 122.893 1.00 122.92 ? 302 LEU A CA  1 
ATOM   1943 C C   . LEU A 1 302 ? 185.598 153.869 123.141 1.00 122.92 ? 302 LEU A C   1 
ATOM   1944 O O   . LEU A 1 302 ? 185.537 153.357 124.262 1.00 122.92 ? 302 LEU A O   1 
ATOM   1945 C CB  . LEU A 1 302 ? 185.853 156.336 123.436 1.00 122.92 ? 302 LEU A CB  1 
ATOM   1946 C CG  . LEU A 1 302 ? 186.739 157.580 123.445 1.00 122.92 ? 302 LEU A CG  1 
ATOM   1947 C CD1 . LEU A 1 302 ? 185.928 158.806 123.816 1.00 122.92 ? 302 LEU A CD1 1 
ATOM   1948 C CD2 . LEU A 1 302 ? 187.899 157.390 124.408 1.00 122.92 ? 302 LEU A CD2 1 
ATOM   1949 N N   . ALA A 1 303 ? 184.885 153.425 122.109 1.00 121.47 ? 303 ALA A N   1 
ATOM   1950 C CA  . ALA A 1 303 ? 183.856 152.405 122.261 1.00 121.47 ? 303 ALA A CA  1 
ATOM   1951 C C   . ALA A 1 303 ? 184.383 151.134 122.916 1.00 121.47 ? 303 ALA A C   1 
ATOM   1952 O O   . ALA A 1 303 ? 183.791 150.635 123.879 1.00 121.47 ? 303 ALA A O   1 
ATOM   1953 C CB  . ALA A 1 303 ? 183.245 152.073 120.900 1.00 121.47 ? 303 ALA A CB  1 
ATOM   1954 N N   . PHE A 1 304 ? 185.498 150.610 122.408 1.00 124.07 ? 304 PHE A N   1 
ATOM   1955 C CA  . PHE A 1 304 ? 186.055 149.357 122.901 1.00 124.07 ? 304 PHE A CA  1 
ATOM   1956 C C   . PHE A 1 304 ? 186.470 149.441 124.363 1.00 124.07 ? 304 PHE A C   1 
ATOM   1957 O O   . PHE A 1 304 ? 186.196 148.519 125.140 1.00 124.07 ? 304 PHE A O   1 
ATOM   1958 C CB  . PHE A 1 304 ? 187.260 148.947 122.053 1.00 124.07 ? 304 PHE A CB  1 
ATOM   1959 C CG  . PHE A 1 304 ? 187.005 148.990 120.576 1.00 124.07 ? 304 PHE A CG  1 
ATOM   1960 C CD1 . PHE A 1 304 ? 185.865 148.418 120.039 1.00 124.07 ? 304 PHE A CD1 1 
ATOM   1961 C CD2 . PHE A 1 304 ? 187.906 149.601 119.724 1.00 124.07 ? 304 PHE A CD2 1 
ATOM   1962 C CE1 . PHE A 1 304 ? 185.631 148.457 118.680 1.00 124.07 ? 304 PHE A CE1 1 
ATOM   1963 C CE2 . PHE A 1 304 ? 187.676 149.644 118.365 1.00 124.07 ? 304 PHE A CE2 1 
ATOM   1964 C CZ  . PHE A 1 304 ? 186.537 149.071 117.842 1.00 124.07 ? 304 PHE A CZ  1 
ATOM   1965 N N   . PHE A 1 305 ? 187.127 150.535 124.749 1.00 124.00 ? 305 PHE A N   1 
ATOM   1966 C CA  . PHE A 1 305 ? 187.610 150.667 126.118 1.00 124.00 ? 305 PHE A CA  1 
ATOM   1967 C C   . PHE A 1 305 ? 186.448 150.765 127.096 1.00 124.00 ? 305 PHE A C   1 
ATOM   1968 O O   . PHE A 1 305 ? 186.437 150.101 128.143 1.00 124.00 ? 305 PHE A O   1 
ATOM   1969 C CB  . PHE A 1 305 ? 188.515 151.893 126.227 1.00 124.00 ? 305 PHE A CB  1 
ATOM   1970 C CG  . PHE A 1 305 ? 189.680 151.878 125.273 1.00 124.00 ? 305 PHE A CG  1 
ATOM   1971 C CD1 . PHE A 1 305 ? 190.134 150.689 124.720 1.00 124.00 ? 305 PHE A CD1 1 
ATOM   1972 C CD2 . PHE A 1 305 ? 190.310 153.057 124.913 1.00 124.00 ? 305 PHE A CD2 1 
ATOM   1973 C CE1 . PHE A 1 305 ? 191.198 150.676 123.838 1.00 124.00 ? 305 PHE A CE1 1 
ATOM   1974 C CE2 . PHE A 1 305 ? 191.377 153.050 124.033 1.00 124.00 ? 305 PHE A CE2 1 
ATOM   1975 C CZ  . PHE A 1 305 ? 191.820 151.857 123.496 1.00 124.00 ? 305 PHE A CZ  1 
ATOM   1976 N N   . SER A 1 306 ? 185.453 151.585 126.758 1.00 117.60 ? 306 SER A N   1 
ATOM   1977 C CA  . SER A 1 306 ? 184.271 151.698 127.600 1.00 117.60 ? 306 SER A CA  1 
ATOM   1978 C C   . SER A 1 306 ? 183.556 150.364 127.707 1.00 117.60 ? 306 SER A C   1 
ATOM   1979 O O   . SER A 1 306 ? 183.079 149.997 128.783 1.00 117.60 ? 306 SER A O   1 
ATOM   1980 C CB  . SER A 1 306 ? 183.327 152.766 127.048 1.00 117.60 ? 306 SER A CB  1 
ATOM   1981 O OG  . SER A 1 306 ? 183.953 154.034 127.019 1.00 117.60 ? 306 SER A OG  1 
ATOM   1982 N N   . PHE A 1 307 ? 183.475 149.616 126.607 1.00 113.92 ? 307 PHE A N   1 
ATOM   1983 C CA  . PHE A 1 307 ? 182.778 148.339 126.664 1.00 113.92 ? 307 PHE A CA  1 
ATOM   1984 C C   . PHE A 1 307 ? 183.530 147.336 127.529 1.00 113.92 ? 307 PHE A C   1 
ATOM   1985 O O   . PHE A 1 307 ? 182.915 146.562 128.268 1.00 113.92 ? 307 PHE A O   1 
ATOM   1986 C CB  . PHE A 1 307 ? 182.558 147.782 125.262 1.00 113.92 ? 307 PHE A CB  1 
ATOM   1987 C CG  . PHE A 1 307 ? 181.717 146.540 125.240 1.00 113.92 ? 307 PHE A CG  1 
ATOM   1988 C CD1 . PHE A 1 307 ? 182.297 145.291 125.344 1.00 113.92 ? 307 PHE A CD1 1 
ATOM   1989 C CD2 . PHE A 1 307 ? 180.343 146.627 125.141 1.00 113.92 ? 307 PHE A CD2 1 
ATOM   1990 C CE1 . PHE A 1 307 ? 181.524 144.157 125.333 1.00 113.92 ? 307 PHE A CE1 1 
ATOM   1991 C CE2 . PHE A 1 307 ? 179.567 145.496 125.130 1.00 113.92 ? 307 PHE A CE2 1 
ATOM   1992 C CZ  . PHE A 1 307 ? 180.159 144.259 125.229 1.00 113.92 ? 307 PHE A CZ  1 
ATOM   1993 N N   . ALA A 1 308 ? 184.860 147.313 127.437 1.00 112.56 ? 308 ALA A N   1 
ATOM   1994 C CA  . ALA A 1 308 ? 185.620 146.395 128.283 1.00 112.56 ? 308 ALA A CA  1 
ATOM   1995 C C   . ALA A 1 308 ? 185.474 146.744 129.760 1.00 112.56 ? 308 ALA A C   1 
ATOM   1996 O O   . ALA A 1 308 ? 185.315 145.845 130.601 1.00 112.56 ? 308 ALA A O   1 
ATOM   1997 C CB  . ALA A 1 308 ? 187.091 146.393 127.875 1.00 112.56 ? 308 ALA A CB  1 
ATOM   1998 N N   . ILE A 1 309 ? 185.520 148.034 130.097 1.00 108.66 ? 309 ILE A N   1 
ATOM   1999 C CA  . ILE A 1 309 ? 185.234 148.426 131.468 1.00 108.66 ? 309 ILE A CA  1 
ATOM   2000 C C   . ILE A 1 309 ? 183.824 148.024 131.868 1.00 108.66 ? 309 ILE A C   1 
ATOM   2001 O O   . ILE A 1 309 ? 183.599 147.612 133.012 1.00 108.66 ? 309 ILE A O   1 
ATOM   2002 C CB  . ILE A 1 309 ? 185.447 149.936 131.653 1.00 108.66 ? 309 ILE A CB  1 
ATOM   2003 C CG1 . ILE A 1 309 ? 186.890 150.296 131.308 1.00 108.66 ? 309 ILE A CG1 1 
ATOM   2004 C CG2 . ILE A 1 309 ? 185.107 150.359 133.072 1.00 108.66 ? 309 ILE A CG2 1 
ATOM   2005 C CD1 . ILE A 1 309 ? 187.904 149.605 132.187 1.00 108.66 ? 309 ILE A CD1 1 
ATOM   2006 N N   . PHE A 1 310 ? 182.866 148.126 130.949 1.00 104.18 ? 310 PHE A N   1 
ATOM   2007 C CA  . PHE A 1 310 ? 181.514 147.681 131.248 1.00 104.18 ? 310 PHE A CA  1 
ATOM   2008 C C   . PHE A 1 310 ? 181.493 146.202 131.567 1.00 104.18 ? 310 PHE A C   1 
ATOM   2009 O O   . PHE A 1 310 ? 180.769 145.770 132.460 1.00 104.18 ? 310 PHE A O   1 
ATOM   2010 C CB  . PHE A 1 310 ? 180.576 147.956 130.081 1.00 104.18 ? 310 PHE A CB  1 
ATOM   2011 C CG  . PHE A 1 310 ? 179.353 147.087 130.092 1.00 104.18 ? 310 PHE A CG  1 
ATOM   2012 C CD1 . PHE A 1 310 ? 178.404 147.220 131.089 1.00 104.18 ? 310 PHE A CD1 1 
ATOM   2013 C CD2 . PHE A 1 310 ? 179.169 146.111 129.129 1.00 104.18 ? 310 PHE A CD2 1 
ATOM   2014 C CE1 . PHE A 1 310 ? 177.284 146.415 131.108 1.00 104.18 ? 310 PHE A CE1 1 
ATOM   2015 C CE2 . PHE A 1 310 ? 178.052 145.300 129.147 1.00 104.18 ? 310 PHE A CE2 1 
ATOM   2016 C CZ  . PHE A 1 310 ? 177.109 145.452 130.134 1.00 104.18 ? 310 PHE A CZ  1 
ATOM   2017 N N   . VAL A 1 311 ? 182.250 145.404 130.818 1.00 102.51 ? 311 VAL A N   1 
ATOM   2018 C CA  . VAL A 1 311 ? 182.283 143.967 131.077 1.00 102.51 ? 311 VAL A CA  1 
ATOM   2019 C C   . VAL A 1 311 ? 182.848 143.691 132.461 1.00 102.51 ? 311 VAL A C   1 
ATOM   2020 O O   . VAL A 1 311 ? 182.292 142.893 133.228 1.00 102.51 ? 311 VAL A O   1 
ATOM   2021 C CB  . VAL A 1 311 ? 183.088 143.238 129.991 1.00 102.51 ? 311 VAL A CB  1 
ATOM   2022 C CG1 . VAL A 1 311 ? 183.206 141.773 130.333 1.00 102.51 ? 311 VAL A CG1 1 
ATOM   2023 C CG2 . VAL A 1 311 ? 182.412 143.391 128.655 1.00 102.51 ? 311 VAL A CG2 1 
ATOM   2024 N N   . VAL A 1 312 ? 183.952 144.351 132.808 1.00 100.16 ? 312 VAL A N   1 
ATOM   2025 C CA  . VAL A 1 312 ? 184.544 144.149 134.129 1.00 100.16 ? 312 VAL A CA  1 
ATOM   2026 C C   . VAL A 1 312 ? 183.540 144.500 135.219 1.00 100.16 ? 312 VAL A C   1 
ATOM   2027 O O   . VAL A 1 312 ? 183.293 143.713 136.144 1.00 100.16 ? 312 VAL A O   1 
ATOM   2028 C CB  . VAL A 1 312 ? 185.833 144.974 134.271 1.00 100.16 ? 312 VAL A CB  1 
ATOM   2029 C CG1 . VAL A 1 312 ? 186.214 145.104 135.730 1.00 100.16 ? 312 VAL A CG1 1 
ATOM   2030 C CG2 . VAL A 1 312 ? 186.952 144.325 133.489 1.00 100.16 ? 312 VAL A CG2 1 
ATOM   2031 N N   . ALA A 1 313 ? 182.937 145.684 135.117 1.00 95.79  ? 313 ALA A N   1 
ATOM   2032 C CA  . ALA A 1 313 ? 182.012 146.129 136.149 1.00 95.79  ? 313 ALA A CA  1 
ATOM   2033 C C   . ALA A 1 313 ? 180.752 145.283 136.180 1.00 95.79  ? 313 ALA A C   1 
ATOM   2034 O O   . ALA A 1 313 ? 180.192 145.061 137.252 1.00 95.79  ? 313 ALA A O   1 
ATOM   2035 C CB  . ALA A 1 313 ? 181.661 147.597 135.948 1.00 95.79  ? 313 ALA A CB  1 
ATOM   2036 N N   . TRP A 1 314 ? 180.290 144.801 135.029 1.00 94.91  ? 314 TRP A N   1 
ATOM   2037 C CA  . TRP A 1 314 ? 179.124 143.933 135.003 1.00 94.91  ? 314 TRP A CA  1 
ATOM   2038 C C   . TRP A 1 314 ? 179.410 142.644 135.744 1.00 94.91  ? 314 TRP A C   1 
ATOM   2039 O O   . TRP A 1 314 ? 178.663 142.271 136.655 1.00 94.91  ? 314 TRP A O   1 
ATOM   2040 C CB  . TRP A 1 314 ? 178.712 143.645 133.561 1.00 94.91  ? 314 TRP A CB  1 
ATOM   2041 C CG  . TRP A 1 314 ? 177.647 142.600 133.410 1.00 94.91  ? 314 TRP A CG  1 
ATOM   2042 C CD1 . TRP A 1 314 ? 177.793 141.256 133.539 1.00 94.91  ? 314 TRP A CD1 1 
ATOM   2043 C CD2 . TRP A 1 314 ? 176.276 142.823 133.082 1.00 94.91  ? 314 TRP A CD2 1 
ATOM   2044 N NE1 . TRP A 1 314 ? 176.598 140.627 133.324 1.00 94.91  ? 314 TRP A NE1 1 
ATOM   2045 C CE2 . TRP A 1 314 ? 175.650 141.569 133.040 1.00 94.91  ? 314 TRP A CE2 1 
ATOM   2046 C CE3 . TRP A 1 314 ? 175.517 143.965 132.825 1.00 94.91  ? 314 TRP A CE3 1 
ATOM   2047 C CZ2 . TRP A 1 314 ? 174.303 141.423 132.751 1.00 94.91  ? 314 TRP A CZ2 1 
ATOM   2048 C CZ3 . TRP A 1 314 ? 174.180 143.818 132.538 1.00 94.91  ? 314 TRP A CZ3 1 
ATOM   2049 C CH2 . TRP A 1 314 ? 173.586 142.558 132.505 1.00 94.91  ? 314 TRP A CH2 1 
ATOM   2050 N N   . ILE A 1 315 ? 180.508 141.970 135.386 1.00 94.86  ? 315 ILE A N   1 
ATOM   2051 C CA  . ILE A 1 315 ? 180.914 140.770 136.114 1.00 94.86  ? 315 ILE A CA  1 
ATOM   2052 C C   . ILE A 1 315 ? 180.913 141.046 137.605 1.00 94.86  ? 315 ILE A C   1 
ATOM   2053 O O   . ILE A 1 315 ? 180.089 140.498 138.351 1.00 94.86  ? 315 ILE A O   1 
ATOM   2054 C CB  . ILE A 1 315 ? 182.298 140.288 135.645 1.00 94.86  ? 315 ILE A CB  1 
ATOM   2055 C CG1 . ILE A 1 315 ? 182.286 139.969 134.156 1.00 94.86  ? 315 ILE A CG1 1 
ATOM   2056 C CG2 . ILE A 1 315 ? 182.742 139.086 136.451 1.00 94.86  ? 315 ILE A CG2 1 
ATOM   2057 C CD1 . ILE A 1 315 ? 181.332 138.885 133.802 1.00 94.86  ? 315 ILE A CD1 1 
ATOM   2058 N N   . TYR A 1 316 ? 181.753 141.993 138.038 1.00 92.56  ? 316 TYR A N   1 
ATOM   2059 C CA  . TYR A 1 316 ? 181.897 142.244 139.467 1.00 92.56  ? 316 TYR A CA  1 
ATOM   2060 C C   . TYR A 1 316 ? 180.557 142.579 140.101 1.00 92.56  ? 316 TYR A C   1 
ATOM   2061 O O   . TYR A 1 316 ? 179.976 141.743 140.799 1.00 92.56  ? 316 TYR A O   1 
ATOM   2062 C CB  . TYR A 1 316 ? 182.888 143.373 139.716 1.00 92.56  ? 316 TYR A CB  1 
ATOM   2063 C CG  . TYR A 1 316 ? 182.893 143.818 141.154 1.00 92.56  ? 316 TYR A CG  1 
ATOM   2064 C CD1 . TYR A 1 316 ? 183.439 143.017 142.141 1.00 92.56  ? 316 TYR A CD1 1 
ATOM   2065 C CD2 . TYR A 1 316 ? 182.345 145.030 141.527 1.00 92.56  ? 316 TYR A CD2 1 
ATOM   2066 C CE1 . TYR A 1 316 ? 183.445 143.412 143.458 1.00 92.56  ? 316 TYR A CE1 1 
ATOM   2067 C CE2 . TYR A 1 316 ? 182.346 145.434 142.846 1.00 92.56  ? 316 TYR A CE2 1 
ATOM   2068 C CZ  . TYR A 1 316 ? 182.897 144.619 143.806 1.00 92.56  ? 316 TYR A CZ  1 
ATOM   2069 O OH  . TYR A 1 316 ? 182.903 145.012 145.122 1.00 92.56  ? 316 TYR A OH  1 
ATOM   2070 N N   . LEU A 1 317 ? 179.996 143.743 139.766 1.00 90.05  ? 317 LEU A N   1 
ATOM   2071 C CA  . LEU A 1 317 ? 178.777 144.188 140.422 1.00 90.05  ? 317 LEU A CA  1 
ATOM   2072 C C   . LEU A 1 317 ? 177.691 143.140 140.314 1.00 90.05  ? 317 LEU A C   1 
ATOM   2073 O O   . LEU A 1 317 ? 177.412 142.439 141.290 1.00 90.05  ? 317 LEU A O   1 
ATOM   2074 C CB  . LEU A 1 317 ? 178.289 145.498 139.810 1.00 90.05  ? 317 LEU A CB  1 
ATOM   2075 C CG  . LEU A 1 317 ? 179.090 146.764 140.082 1.00 90.05  ? 317 LEU A CG  1 
ATOM   2076 C CD1 . LEU A 1 317 ? 178.618 147.857 139.162 1.00 90.05  ? 317 LEU A CD1 1 
ATOM   2077 C CD2 . LEU A 1 317 ? 178.933 147.185 141.521 1.00 90.05  ? 317 LEU A CD2 1 
ATOM   2078 N N   . ARG A 1 318 ? 177.162 142.921 139.114 1.00 91.59  ? 318 ARG A N   1 
ATOM   2079 C CA  . ARG A 1 318 ? 175.993 142.067 139.048 1.00 91.59  ? 318 ARG A CA  1 
ATOM   2080 C C   . ARG A 1 318 ? 176.300 140.672 139.560 1.00 91.59  ? 318 ARG A C   1 
ATOM   2081 O O   . ARG A 1 318 ? 175.764 140.273 140.597 1.00 91.59  ? 318 ARG A O   1 
ATOM   2082 C CB  . ARG A 1 318 ? 175.440 142.029 137.631 1.00 91.59  ? 318 ARG A CB  1 
ATOM   2083 C CG  . ARG A 1 318 ? 174.458 143.154 137.351 1.00 91.59  ? 318 ARG A CG  1 
ATOM   2084 C CD  . ARG A 1 318 ? 174.054 143.140 135.907 1.00 91.59  ? 318 ARG A CD  1 
ATOM   2085 N NE  . ARG A 1 318 ? 173.122 144.200 135.549 1.00 91.59  ? 318 ARG A NE  1 
ATOM   2086 C CZ  . ARG A 1 318 ? 171.825 144.013 135.341 1.00 91.59  ? 318 ARG A CZ  1 
ATOM   2087 N NH1 . ARG A 1 318 ? 171.304 142.801 135.458 1.00 91.59  ? 318 ARG A NH1 1 
ATOM   2088 N NH2 . ARG A 1 318 ? 171.048 145.034 135.009 1.00 91.59  ? 318 ARG A NH2 1 
ATOM   2089 N N   . HIS A 1 319 ? 177.203 139.936 138.914 1.00 93.82  ? 319 HIS A N   1 
ATOM   2090 C CA  . HIS A 1 319 ? 177.294 138.535 139.289 1.00 93.82  ? 319 HIS A CA  1 
ATOM   2091 C C   . HIS A 1 319 ? 177.901 138.350 140.676 1.00 93.82  ? 319 HIS A C   1 
ATOM   2092 O O   . HIS A 1 319 ? 177.308 137.666 141.516 1.00 93.82  ? 319 HIS A O   1 
ATOM   2093 C CB  . HIS A 1 319 ? 178.065 137.769 138.225 1.00 93.82  ? 319 HIS A CB  1 
ATOM   2094 C CG  . HIS A 1 319 ? 177.219 137.395 137.050 1.00 93.82  ? 319 HIS A CG  1 
ATOM   2095 N ND1 . HIS A 1 319 ? 176.927 138.279 136.036 1.00 93.82  ? 319 HIS A ND1 1 
ATOM   2096 C CD2 . HIS A 1 319 ? 176.569 136.247 136.748 1.00 93.82  ? 319 HIS A CD2 1 
ATOM   2097 C CE1 . HIS A 1 319 ? 176.149 137.686 135.148 1.00 93.82  ? 319 HIS A CE1 1 
ATOM   2098 N NE2 . HIS A 1 319 ? 175.918 136.453 135.556 1.00 93.82  ? 319 HIS A NE2 1 
ATOM   2099 N N   . TYR A 1 320 ? 179.040 138.977 140.969 1.00 88.37  ? 320 TYR A N   1 
ATOM   2100 C CA  . TYR A 1 320 ? 179.638 138.727 142.268 1.00 88.37  ? 320 TYR A CA  1 
ATOM   2101 C C   . TYR A 1 320 ? 178.808 139.295 143.409 1.00 88.37  ? 320 TYR A C   1 
ATOM   2102 O O   . TYR A 1 320 ? 178.581 138.594 144.399 1.00 88.37  ? 320 TYR A O   1 
ATOM   2103 C CB  . TYR A 1 320 ? 181.048 139.309 142.321 1.00 88.37  ? 320 TYR A CB  1 
ATOM   2104 C CG  . TYR A 1 320 ? 181.662 139.257 143.691 1.00 88.37  ? 320 TYR A CG  1 
ATOM   2105 C CD1 . TYR A 1 320 ? 182.175 140.395 144.280 1.00 88.37  ? 320 TYR A CD1 1 
ATOM   2106 C CD2 . TYR A 1 320 ? 181.729 138.069 144.396 1.00 88.37  ? 320 TYR A CD2 1 
ATOM   2107 C CE1 . TYR A 1 320 ? 182.736 140.358 145.530 1.00 88.37  ? 320 TYR A CE1 1 
ATOM   2108 C CE2 . TYR A 1 320 ? 182.288 138.019 145.647 1.00 88.37  ? 320 TYR A CE2 1 
ATOM   2109 C CZ  . TYR A 1 320 ? 182.791 139.168 146.211 1.00 88.37  ? 320 TYR A CZ  1 
ATOM   2110 O OH  . TYR A 1 320 ? 183.352 139.133 147.465 1.00 88.37  ? 320 TYR A OH  1 
ATOM   2111 N N   . ILE A 1 321 ? 178.361 140.547 143.324 1.00 86.99  ? 321 ILE A N   1 
ATOM   2112 C CA  . ILE A 1 321 ? 177.592 141.109 144.417 1.00 86.99  ? 321 ILE A CA  1 
ATOM   2113 C C   . ILE A 1 321 ? 176.256 140.400 144.603 1.00 86.99  ? 321 ILE A C   1 
ATOM   2114 O O   . ILE A 1 321 ? 175.883 140.094 145.735 1.00 86.99  ? 321 ILE A O   1 
ATOM   2115 C CB  . ILE A 1 321 ? 177.398 142.614 144.197 1.00 86.99  ? 321 ILE A CB  1 
ATOM   2116 C CG1 . ILE A 1 321 ? 178.748 143.320 144.221 1.00 86.99  ? 321 ILE A CG1 1 
ATOM   2117 C CG2 . ILE A 1 321 ? 176.497 143.188 145.254 1.00 86.99  ? 321 ILE A CG2 1 
ATOM   2118 C CD1 . ILE A 1 321 ? 179.476 143.175 145.517 1.00 86.99  ? 321 ILE A CD1 1 
ATOM   2119 N N   . ASN A 1 322 ? 175.516 140.108 143.532 1.00 84.30  ? 322 ASN A N   1 
ATOM   2120 C CA  . ASN A 1 322 ? 174.251 139.421 143.733 1.00 84.30  ? 322 ASN A CA  1 
ATOM   2121 C C   . ASN A 1 322 ? 174.465 137.995 144.227 1.00 84.30  ? 322 ASN A C   1 
ATOM   2122 O O   . ASN A 1 322 ? 173.664 137.488 145.020 1.00 84.30  ? 322 ASN A O   1 
ATOM   2123 C CB  . ASN A 1 322 ? 173.435 139.438 142.443 1.00 84.30  ? 322 ASN A CB  1 
ATOM   2124 C CG  . ASN A 1 322 ? 172.877 140.813 142.129 1.00 84.30  ? 322 ASN A CG  1 
ATOM   2125 O OD1 . ASN A 1 322 ? 173.391 141.825 142.597 1.00 84.30  ? 322 ASN A OD1 1 
ATOM   2126 N ND2 . ASN A 1 322 ? 171.819 140.856 141.332 1.00 84.30  ? 322 ASN A ND2 1 
ATOM   2127 N N   . LEU A 1 323 ? 175.546 137.330 143.809 1.00 87.83  ? 323 LEU A N   1 
ATOM   2128 C CA  . LEU A 1 323 ? 175.796 135.988 144.316 1.00 87.83  ? 323 LEU A CA  1 
ATOM   2129 C C   . LEU A 1 323 ? 176.184 136.005 145.787 1.00 87.83  ? 323 LEU A C   1 
ATOM   2130 O O   . LEU A 1 323 ? 175.741 135.139 146.552 1.00 87.83  ? 323 LEU A O   1 
ATOM   2131 C CB  . LEU A 1 323 ? 176.872 135.302 143.481 1.00 87.83  ? 323 LEU A CB  1 
ATOM   2132 C CG  . LEU A 1 323 ? 176.366 134.674 142.181 1.00 87.83  ? 323 LEU A CG  1 
ATOM   2133 C CD1 . LEU A 1 323 ? 177.524 134.276 141.290 1.00 87.83  ? 323 LEU A CD1 1 
ATOM   2134 C CD2 . LEU A 1 323 ? 175.488 133.476 142.468 1.00 87.83  ? 323 LEU A CD2 1 
ATOM   2135 N N   . LYS A 1 324 ? 177.001 136.969 146.212 1.00 84.23  ? 324 LYS A N   1 
ATOM   2136 C CA  . LYS A 1 324 ? 177.292 137.050 147.635 1.00 84.23  ? 324 LYS A CA  1 
ATOM   2137 C C   . LYS A 1 324 ? 176.061 137.466 148.421 1.00 84.23  ? 324 LYS A C   1 
ATOM   2138 O O   . LYS A 1 324 ? 175.910 137.064 149.576 1.00 84.23  ? 324 LYS A O   1 
ATOM   2139 C CB  . LYS A 1 324 ? 178.448 138.007 147.915 1.00 84.23  ? 324 LYS A CB  1 
ATOM   2140 C CG  . LYS A 1 324 ? 178.069 139.465 147.913 1.00 84.23  ? 324 LYS A CG  1 
ATOM   2141 C CD  . LYS A 1 324 ? 179.238 140.358 148.286 1.00 84.23  ? 324 LYS A CD  1 
ATOM   2142 C CE  . LYS A 1 324 ? 179.540 140.280 149.767 1.00 84.23  ? 324 LYS A CE  1 
ATOM   2143 N NZ  . LYS A 1 324 ? 180.564 141.276 150.170 1.00 84.23  ? 324 LYS A NZ  1 
ATOM   2144 N N   . ILE A 1 325 ? 175.150 138.223 147.808 1.00 83.99  ? 325 ILE A N   1 
ATOM   2145 C CA  . ILE A 1 325 ? 173.893 138.536 148.476 1.00 83.99  ? 325 ILE A CA  1 
ATOM   2146 C C   . ILE A 1 325 ? 173.061 137.277 148.657 1.00 83.99  ? 325 ILE A C   1 
ATOM   2147 O O   . ILE A 1 325 ? 172.411 137.100 149.687 1.00 83.99  ? 325 ILE A O   1 
ATOM   2148 C CB  . ILE A 1 325 ? 173.119 139.616 147.706 1.00 83.99  ? 325 ILE A CB  1 
ATOM   2149 C CG1 . ILE A 1 325 ? 173.683 140.996 148.012 1.00 83.99  ? 325 ILE A CG1 1 
ATOM   2150 C CG2 . ILE A 1 325 ? 171.663 139.596 148.092 1.00 83.99  ? 325 ILE A CG2 1 
ATOM   2151 C CD1 . ILE A 1 325 ? 172.961 142.091 147.294 1.00 83.99  ? 325 ILE A CD1 1 
ATOM   2152 N N   . LEU A 1 326 ? 173.055 136.387 147.665 1.00 84.82  ? 326 LEU A N   1 
ATOM   2153 C CA  . LEU A 1 326 ? 172.333 135.126 147.820 1.00 84.82  ? 326 LEU A CA  1 
ATOM   2154 C C   . LEU A 1 326 ? 172.955 134.257 148.906 1.00 84.82  ? 326 LEU A C   1 
ATOM   2155 O O   . LEU A 1 326 ? 172.245 133.676 149.744 1.00 84.82  ? 326 LEU A O   1 
ATOM   2156 C CB  . LEU A 1 326 ? 172.302 134.375 146.498 1.00 84.82  ? 326 LEU A CB  1 
ATOM   2157 C CG  . LEU A 1 326 ? 171.337 134.973 145.491 1.00 84.82  ? 326 LEU A CG  1 
ATOM   2158 C CD1 . LEU A 1 326 ? 171.350 134.168 144.213 1.00 84.82  ? 326 LEU A CD1 1 
ATOM   2159 C CD2 . LEU A 1 326 ? 169.962 135.008 146.093 1.00 84.82  ? 326 LEU A CD2 1 
ATOM   2160 N N   . TRP A 1 327 ? 174.279 134.140 148.903 1.00 87.88  ? 327 TRP A N   1 
ATOM   2161 C CA  . TRP A 1 327 ? 174.930 133.419 149.988 1.00 87.88  ? 327 TRP A CA  1 
ATOM   2162 C C   . TRP A 1 327 ? 174.556 134.030 151.329 1.00 87.88  ? 327 TRP A C   1 
ATOM   2163 O O   . TRP A 1 327 ? 174.350 133.317 152.323 1.00 87.88  ? 327 TRP A O   1 
ATOM   2164 C CB  . TRP A 1 327 ? 176.442 133.426 149.810 1.00 87.88  ? 327 TRP A CB  1 
ATOM   2165 C CG  . TRP A 1 327 ? 177.103 132.577 150.814 1.00 87.88  ? 327 TRP A CG  1 
ATOM   2166 C CD1 . TRP A 1 327 ? 178.017 132.964 151.742 1.00 87.88  ? 327 TRP A CD1 1 
ATOM   2167 C CD2 . TRP A 1 327 ? 176.909 131.175 150.998 1.00 87.88  ? 327 TRP A CD2 1 
ATOM   2168 N NE1 . TRP A 1 327 ? 178.401 131.890 152.502 1.00 87.88  ? 327 TRP A NE1 1 
ATOM   2169 C CE2 . TRP A 1 327 ? 177.734 130.778 152.062 1.00 87.88  ? 327 TRP A CE2 1 
ATOM   2170 C CE3 . TRP A 1 327 ? 176.116 130.216 150.364 1.00 87.88  ? 327 TRP A CE3 1 
ATOM   2171 C CZ2 . TRP A 1 327 ? 177.790 129.466 152.508 1.00 87.88  ? 327 TRP A CZ2 1 
ATOM   2172 C CZ3 . TRP A 1 327 ? 176.170 128.918 150.807 1.00 87.88  ? 327 TRP A CZ3 1 
ATOM   2173 C CH2 . TRP A 1 327 ? 177.001 128.552 151.870 1.00 87.88  ? 327 TRP A CH2 1 
ATOM   2174 N N   . SER A 1 328 ? 174.450 135.357 151.365 1.00 86.02  ? 328 SER A N   1 
ATOM   2175 C CA  . SER A 1 328 ? 174.022 136.039 152.572 1.00 86.02  ? 328 SER A CA  1 
ATOM   2176 C C   . SER A 1 328 ? 172.602 135.657 152.937 1.00 86.02  ? 328 SER A C   1 
ATOM   2177 O O   . SER A 1 328 ? 172.310 135.418 154.107 1.00 86.02  ? 328 SER A O   1 
ATOM   2178 C CB  . SER A 1 328 ? 174.125 137.544 152.387 1.00 86.02  ? 328 SER A CB  1 
ATOM   2179 O OG  . SER A 1 328 ? 173.035 138.008 151.621 1.00 86.02  ? 328 SER A OG  1 
ATOM   2180 N N   . VAL A 1 329 ? 171.703 135.584 151.955 1.00 84.10  ? 329 VAL A N   1 
ATOM   2181 C CA  . VAL A 1 329 ? 170.309 135.353 152.311 1.00 84.10  ? 329 VAL A CA  1 
ATOM   2182 C C   . VAL A 1 329 ? 170.302 134.022 153.029 1.00 84.10  ? 329 VAL A C   1 
ATOM   2183 O O   . VAL A 1 329 ? 169.800 133.948 154.144 1.00 84.10  ? 329 VAL A O   1 
ATOM   2184 C CB  . VAL A 1 329 ? 169.296 135.378 151.146 1.00 84.10  ? 329 VAL A CB  1 
ATOM   2185 C CG1 . VAL A 1 329 ? 169.372 136.683 150.370 1.00 84.10  ? 329 VAL A CG1 1 
ATOM   2186 C CG2 . VAL A 1 329 ? 169.358 134.162 150.267 1.00 84.10  ? 329 VAL A CG2 1 
ATOM   2187 N N   . LEU A 1 330 ? 171.006 133.019 152.506 1.00 85.90  ? 330 LEU A N   1 
ATOM   2188 C CA  . LEU A 1 330 ? 171.048 131.747 153.232 1.00 85.90  ? 330 LEU A CA  1 
ATOM   2189 C C   . LEU A 1 330 ? 171.609 131.932 154.641 1.00 85.90  ? 330 LEU A C   1 
ATOM   2190 O O   . LEU A 1 330 ? 170.874 131.882 155.648 1.00 85.90  ? 330 LEU A O   1 
ATOM   2191 C CB  . LEU A 1 330 ? 171.895 130.722 152.479 1.00 85.90  ? 330 LEU A CB  1 
ATOM   2192 C CG  . LEU A 1 330 ? 171.294 129.904 151.337 1.00 85.90  ? 330 LEU A CG  1 
ATOM   2193 C CD1 . LEU A 1 330 ? 170.164 129.026 151.840 1.00 85.90  ? 330 LEU A CD1 1 
ATOM   2194 C CD2 . LEU A 1 330 ? 170.847 130.774 150.203 1.00 85.90  ? 330 LEU A CD2 1 
ATOM   2195 N N   . THR A 1 331 ? 172.903 132.245 154.723 1.00 89.03  ? 331 THR A N   1 
ATOM   2196 C CA  . THR A 1 331 ? 173.617 132.056 155.981 1.00 89.03  ? 331 THR A CA  1 
ATOM   2197 C C   . THR A 1 331 ? 173.222 133.097 157.023 1.00 89.03  ? 331 THR A C   1 
ATOM   2198 O O   . THR A 1 331 ? 173.135 132.784 158.215 1.00 89.03  ? 331 THR A O   1 
ATOM   2199 C CB  . THR A 1 331 ? 175.128 132.059 155.735 1.00 89.03  ? 331 THR A CB  1 
ATOM   2200 O OG1 . THR A 1 331 ? 175.812 131.708 156.943 1.00 89.03  ? 331 THR A OG1 1 
ATOM   2201 C CG2 . THR A 1 331 ? 175.616 133.416 155.255 1.00 89.03  ? 331 THR A CG2 1 
ATOM   2202 N N   . GLN A 1 332 ? 172.982 134.336 156.605 1.00 87.52  ? 332 GLN A N   1 
ATOM   2203 C CA  . GLN A 1 332 ? 172.615 135.415 157.503 1.00 87.52  ? 332 GLN A CA  1 
ATOM   2204 C C   . GLN A 1 332 ? 171.139 135.759 157.409 1.00 87.52  ? 332 GLN A C   1 
ATOM   2205 O O   . GLN A 1 332 ? 170.726 136.812 157.894 1.00 87.52  ? 332 GLN A O   1 
ATOM   2206 C CB  . GLN A 1 332 ? 173.464 136.647 157.208 1.00 87.52  ? 332 GLN A CB  1 
ATOM   2207 C CG  . GLN A 1 332 ? 174.782 136.655 157.936 1.00 87.52  ? 332 GLN A CG  1 
ATOM   2208 C CD  . GLN A 1 332 ? 175.794 137.549 157.271 1.00 87.52  ? 332 GLN A CD  1 
ATOM   2209 O OE1 . GLN A 1 332 ? 176.177 138.586 157.810 1.00 87.52  ? 332 GLN A OE1 1 
ATOM   2210 N NE2 . GLN A 1 332 ? 176.230 137.158 156.082 1.00 87.52  ? 332 GLN A NE2 1 
ATOM   2211 N N   . PHE A 1 333 ? 170.337 134.905 156.785 1.00 79.19  ? 333 PHE A N   1 
ATOM   2212 C CA  . PHE A 1 333 ? 168.903 134.963 156.969 1.00 79.19  ? 333 PHE A CA  1 
ATOM   2213 C C   . PHE A 1 333 ? 168.526 134.029 158.091 1.00 79.19  ? 333 PHE A C   1 
ATOM   2214 O O   . PHE A 1 333 ? 167.703 134.364 158.944 1.00 79.19  ? 333 PHE A O   1 
ATOM   2215 C CB  . PHE A 1 333 ? 168.217 134.540 155.677 1.00 79.19  ? 333 PHE A CB  1 
ATOM   2216 C CG  . PHE A 1 333 ? 166.919 135.211 155.397 1.00 79.19  ? 333 PHE A CG  1 
ATOM   2217 C CD1 . PHE A 1 333 ? 166.882 136.500 154.917 1.00 79.19  ? 333 PHE A CD1 1 
ATOM   2218 C CD2 . PHE A 1 333 ? 165.737 134.522 155.530 1.00 79.19  ? 333 PHE A CD2 1 
ATOM   2219 C CE1 . PHE A 1 333 ? 165.689 137.102 154.620 1.00 79.19  ? 333 PHE A CE1 1 
ATOM   2220 C CE2 . PHE A 1 333 ? 164.547 135.119 155.237 1.00 79.19  ? 333 PHE A CE2 1 
ATOM   2221 C CZ  . PHE A 1 333 ? 164.523 136.412 154.781 1.00 79.19  ? 333 PHE A CZ  1 
ATOM   2222 N N   . ARG A 1 334 ? 169.151 132.854 158.119 1.00 84.33  ? 334 ARG A N   1 
ATOM   2223 C CA  . ARG A 1 334 ? 168.802 131.932 159.187 1.00 84.33  ? 334 ARG A CA  1 
ATOM   2224 C C   . ARG A 1 334 ? 169.295 132.413 160.548 1.00 84.33  ? 334 ARG A C   1 
ATOM   2225 O O   . ARG A 1 334 ? 168.639 132.158 161.560 1.00 84.33  ? 334 ARG A O   1 
ATOM   2226 C CB  . ARG A 1 334 ? 169.333 130.534 158.882 1.00 84.33  ? 334 ARG A CB  1 
ATOM   2227 C CG  . ARG A 1 334 ? 168.505 129.821 157.838 1.00 84.33  ? 334 ARG A CG  1 
ATOM   2228 C CD  . ARG A 1 334 ? 169.352 128.942 156.948 1.00 84.33  ? 334 ARG A CD  1 
ATOM   2229 N NE  . ARG A 1 334 ? 169.798 127.729 157.626 1.00 84.33  ? 334 ARG A NE  1 
ATOM   2230 C CZ  . ARG A 1 334 ? 169.002 126.715 157.952 1.00 84.33  ? 334 ARG A CZ  1 
ATOM   2231 N NH1 . ARG A 1 334 ? 169.501 125.649 158.564 1.00 84.33  ? 334 ARG A NH1 1 
ATOM   2232 N NH2 . ARG A 1 334 ? 167.708 126.754 157.657 1.00 84.33  ? 334 ARG A NH2 1 
ATOM   2233 N N   . THR A 1 335 ? 170.436 133.104 160.605 1.00 90.08  ? 335 THR A N   1 
ATOM   2234 C CA  . THR A 1 335 ? 171.032 133.407 161.905 1.00 90.08  ? 335 THR A CA  1 
ATOM   2235 C C   . THR A 1 335 ? 171.551 134.831 162.057 1.00 90.08  ? 335 THR A C   1 
ATOM   2236 O O   . THR A 1 335 ? 172.655 135.023 162.572 1.00 90.08  ? 335 THR A O   1 
ATOM   2237 C CB  . THR A 1 335 ? 172.202 132.462 162.202 1.00 90.08  ? 335 THR A CB  1 
ATOM   2238 O OG1 . THR A 1 335 ? 173.354 132.887 161.465 1.00 90.08  ? 335 THR A OG1 1 
ATOM   2239 C CG2 . THR A 1 335 ? 171.878 131.022 161.847 1.00 90.08  ? 335 THR A CG2 1 
ATOM   2240 N N   . GLU A 1 336 ? 170.802 135.841 161.628 1.00 89.22  ? 336 GLU A N   1 
ATOM   2241 C CA  . GLU A 1 336 ? 171.302 137.192 161.847 1.00 89.22  ? 336 GLU A CA  1 
ATOM   2242 C C   . GLU A 1 336 ? 170.182 138.094 162.361 1.00 89.22  ? 336 GLU A C   1 
ATOM   2243 O O   . GLU A 1 336 ? 169.959 139.193 161.847 1.00 89.22  ? 336 GLU A O   1 
ATOM   2244 C CB  . GLU A 1 336 ? 171.942 137.732 160.565 1.00 89.22  ? 336 GLU A CB  1 
ATOM   2245 C CG  . GLU A 1 336 ? 172.557 139.115 160.678 1.00 89.22  ? 336 GLU A CG  1 
ATOM   2246 C CD  . GLU A 1 336 ? 173.737 139.136 161.624 1.00 89.22  ? 336 GLU A CD  1 
ATOM   2247 O OE1 . GLU A 1 336 ? 174.374 138.077 161.799 1.00 89.22  ? 336 GLU A OE1 1 
ATOM   2248 O OE2 . GLU A 1 336 ? 174.009 140.201 162.217 1.00 89.22  ? 336 GLU A OE2 1 
ATOM   2249 N N   . GLY A 1 337 ? 169.447 137.628 163.357 1.00 87.05  ? 337 GLY A N   1 
ATOM   2250 C CA  . GLY A 1 337 ? 168.389 138.412 163.945 1.00 87.05  ? 337 GLY A CA  1 
ATOM   2251 C C   . GLY A 1 337 ? 167.185 137.557 164.229 1.00 87.05  ? 337 GLY A C   1 
ATOM   2252 O O   . GLY A 1 337 ? 167.278 136.336 164.385 1.00 87.05  ? 337 GLY A O   1 
ATOM   2253 N N   . ASN A 1 338 ? 166.027 138.205 164.303 1.00 77.12  ? 338 ASN A N   1 
ATOM   2254 C CA  . ASN A 1 338 ? 164.793 137.485 164.569 1.00 77.12  ? 338 ASN A CA  1 
ATOM   2255 C C   . ASN A 1 338 ? 164.504 136.513 163.434 1.00 77.12  ? 338 ASN A C   1 
ATOM   2256 O O   . ASN A 1 338 ? 164.526 136.882 162.259 1.00 77.12  ? 338 ASN A O   1 
ATOM   2257 C CB  . ASN A 1 338 ? 163.640 138.472 164.730 1.00 77.12  ? 338 ASN A CB  1 
ATOM   2258 C CG  . ASN A 1 338 ? 162.605 137.998 165.716 1.00 77.12  ? 338 ASN A CG  1 
ATOM   2259 O OD1 . ASN A 1 338 ? 162.811 137.016 166.426 1.00 77.12  ? 338 ASN A OD1 1 
ATOM   2260 N ND2 . ASN A 1 338 ? 161.476 138.693 165.766 1.00 77.12  ? 338 ASN A ND2 1 
ATOM   2261 N N   . TYR A 1 339 ? 164.237 135.256 163.788 1.00 73.32  ? 339 TYR A N   1 
ATOM   2262 C CA  . TYR A 1 339 ? 163.972 134.247 162.770 1.00 73.32  ? 339 TYR A CA  1 
ATOM   2263 C C   . TYR A 1 339 ? 162.821 133.330 163.173 1.00 73.32  ? 339 TYR A C   1 
ATOM   2264 O O   . TYR A 1 339 ? 162.724 132.201 162.682 1.00 73.32  ? 339 TYR A O   1 
ATOM   2265 C CB  . TYR A 1 339 ? 165.239 133.438 162.479 1.00 73.32  ? 339 TYR A CB  1 
ATOM   2266 C CG  . TYR A 1 339 ? 165.131 132.533 161.279 1.00 73.32  ? 339 TYR A CG  1 
ATOM   2267 C CD1 . TYR A 1 339 ? 164.803 133.039 160.038 1.00 73.32  ? 339 TYR A CD1 1 
ATOM   2268 C CD2 . TYR A 1 339 ? 165.356 131.171 161.392 1.00 73.32  ? 339 TYR A CD2 1 
ATOM   2269 C CE1 . TYR A 1 339 ? 164.701 132.220 158.947 1.00 73.32  ? 339 TYR A CE1 1 
ATOM   2270 C CE2 . TYR A 1 339 ? 165.254 130.345 160.303 1.00 73.32  ? 339 TYR A CE2 1 
ATOM   2271 C CZ  . TYR A 1 339 ? 164.926 130.877 159.085 1.00 73.32  ? 339 TYR A CZ  1 
ATOM   2272 O OH  . TYR A 1 339 ? 164.825 130.060 157.992 1.00 73.32  ? 339 TYR A OH  1 
ATOM   2273 N N   . VAL A 1 340 ? 161.943 133.791 164.056 1.00 65.12  ? 340 VAL A N   1 
ATOM   2274 C CA  . VAL A 1 340 ? 160.724 133.077 164.400 1.00 65.12  ? 340 VAL A CA  1 
ATOM   2275 C C   . VAL A 1 340 ? 159.555 133.883 163.862 1.00 65.12  ? 340 VAL A C   1 
ATOM   2276 O O   . VAL A 1 340 ? 159.374 135.046 164.234 1.00 65.12  ? 340 VAL A O   1 
ATOM   2277 C CB  . VAL A 1 340 ? 160.606 132.836 165.913 1.00 65.12  ? 340 VAL A CB  1 
ATOM   2278 C CG1 . VAL A 1 340 ? 161.722 131.947 166.372 1.00 65.12  ? 340 VAL A CG1 1 
ATOM   2279 C CG2 . VAL A 1 340 ? 160.702 134.131 166.673 1.00 65.12  ? 340 VAL A CG2 1 
ATOM   2280 N N   . LEU A 1 341 ? 158.782 133.282 162.967 1.00 59.72  ? 341 LEU A N   1 
ATOM   2281 C CA  . LEU A 1 341 ? 157.668 133.993 162.363 1.00 59.72  ? 341 LEU A CA  1 
ATOM   2282 C C   . LEU A 1 341 ? 156.674 134.428 163.428 1.00 59.72  ? 341 LEU A C   1 
ATOM   2283 O O   . LEU A 1 341 ? 156.310 133.657 164.316 1.00 59.72  ? 341 LEU A O   1 
ATOM   2284 C CB  . LEU A 1 341 ? 156.990 133.123 161.312 1.00 59.72  ? 341 LEU A CB  1 
ATOM   2285 C CG  . LEU A 1 341 ? 155.812 133.729 160.557 1.00 59.72  ? 341 LEU A CG  1 
ATOM   2286 C CD1 . LEU A 1 341 ? 155.798 133.293 159.140 1.00 59.72  ? 341 LEU A CD1 1 
ATOM   2287 C CD2 . LEU A 1 341 ? 154.565 133.219 161.179 1.00 59.72  ? 341 LEU A CD2 1 
ATOM   2288 N N   . ASN A 1 342 ? 156.248 135.683 163.340 1.00 58.52  ? 342 ASN A N   1 
ATOM   2289 C CA  . ASN A 1 342 ? 155.310 136.272 164.288 1.00 58.52  ? 342 ASN A CA  1 
ATOM   2290 C C   . ASN A 1 342 ? 154.388 137.191 163.509 1.00 58.52  ? 342 ASN A C   1 
ATOM   2291 O O   . ASN A 1 342 ? 154.752 138.329 163.221 1.00 58.52  ? 342 ASN A O   1 
ATOM   2292 C CB  . ASN A 1 342 ? 156.039 137.043 165.379 1.00 58.52  ? 342 ASN A CB  1 
ATOM   2293 C CG  . ASN A 1 342 ? 155.113 137.536 166.455 1.00 58.52  ? 342 ASN A CG  1 
ATOM   2294 O OD1 . ASN A 1 342 ? 153.914 137.310 166.404 1.00 58.52  ? 342 ASN A OD1 1 
ATOM   2295 N ND2 . ASN A 1 342 ? 155.665 138.229 167.433 1.00 58.52  ? 342 ASN A ND2 1 
ATOM   2296 N N   . PHE A 1 343 ? 153.202 136.709 163.173 1.00 57.75  ? 343 PHE A N   1 
ATOM   2297 C CA  . PHE A 1 343 ? 152.269 137.512 162.401 1.00 57.75  ? 343 PHE A CA  1 
ATOM   2298 C C   . PHE A 1 343 ? 151.771 138.730 163.154 1.00 57.75  ? 343 PHE A C   1 
ATOM   2299 O O   . PHE A 1 343 ? 151.293 139.669 162.520 1.00 57.75  ? 343 PHE A O   1 
ATOM   2300 C CB  . PHE A 1 343 ? 151.078 136.662 161.981 1.00 57.75  ? 343 PHE A CB  1 
ATOM   2301 C CG  . PHE A 1 343 ? 151.309 135.883 160.736 1.00 57.75  ? 343 PHE A CG  1 
ATOM   2302 C CD1 . PHE A 1 343 ? 151.235 134.514 160.744 1.00 57.75  ? 343 PHE A CD1 1 
ATOM   2303 C CD2 . PHE A 1 343 ? 151.599 136.518 159.558 1.00 57.75  ? 343 PHE A CD2 1 
ATOM   2304 C CE1 . PHE A 1 343 ? 151.446 133.803 159.604 1.00 57.75  ? 343 PHE A CE1 1 
ATOM   2305 C CE2 . PHE A 1 343 ? 151.807 135.806 158.421 1.00 57.75  ? 343 PHE A CE2 1 
ATOM   2306 C CZ  . PHE A 1 343 ? 151.732 134.449 158.444 1.00 57.75  ? 343 PHE A CZ  1 
ATOM   2307 N N   . ALA A 1 344 ? 151.866 138.741 164.477 1.00 58.32  ? 344 ALA A N   1 
ATOM   2308 C CA  . ALA A 1 344 ? 151.373 139.860 165.261 1.00 58.32  ? 344 ALA A CA  1 
ATOM   2309 C C   . ALA A 1 344 ? 152.253 141.090 165.169 1.00 58.32  ? 344 ALA A C   1 
ATOM   2310 O O   . ALA A 1 344 ? 151.732 142.206 165.206 1.00 58.32  ? 344 ALA A O   1 
ATOM   2311 C CB  . ALA A 1 344 ? 151.239 139.462 166.727 1.00 58.32  ? 344 ALA A CB  1 
ATOM   2312 N N   . THR A 1 345 ? 153.567 140.921 165.067 1.00 61.77  ? 345 THR A N   1 
ATOM   2313 C CA  . THR A 1 345 ? 154.494 142.038 164.970 1.00 61.77  ? 345 THR A CA  1 
ATOM   2314 C C   . THR A 1 345 ? 155.031 142.188 163.556 1.00 61.77  ? 345 THR A C   1 
ATOM   2315 O O   . THR A 1 345 ? 156.015 142.891 163.336 1.00 61.77  ? 345 THR A O   1 
ATOM   2316 C CB  . THR A 1 345 ? 155.646 141.882 165.955 1.00 61.77  ? 345 THR A CB  1 
ATOM   2317 O OG1 . THR A 1 345 ? 156.377 140.695 165.644 1.00 61.77  ? 345 THR A OG1 1 
ATOM   2318 C CG2 . THR A 1 345 ? 155.118 141.773 167.357 1.00 61.77  ? 345 THR A CG2 1 
ATOM   2319 N N   . GLN A 1 346 ? 154.392 141.533 162.599 1.00 64.65  ? 346 GLN A N   1 
ATOM   2320 C CA  . GLN A 1 346 ? 154.772 141.587 161.194 1.00 64.65  ? 346 GLN A CA  1 
ATOM   2321 C C   . GLN A 1 346 ? 156.256 141.314 161.020 1.00 64.65  ? 346 GLN A C   1 
ATOM   2322 O O   . GLN A 1 346 ? 156.987 142.060 160.374 1.00 64.65  ? 346 GLN A O   1 
ATOM   2323 C CB  . GLN A 1 346 ? 154.390 142.919 160.570 1.00 64.65  ? 346 GLN A CB  1 
ATOM   2324 C CG  . GLN A 1 346 ? 152.913 143.146 160.468 1.00 64.65  ? 346 GLN A CG  1 
ATOM   2325 C CD  . GLN A 1 346 ? 152.586 144.486 159.861 1.00 64.65  ? 346 GLN A CD  1 
ATOM   2326 O OE1 . GLN A 1 346 ? 153.475 145.279 159.574 1.00 64.65  ? 346 GLN A OE1 1 
ATOM   2327 N NE2 . GLN A 1 346 ? 151.306 144.743 159.647 1.00 64.65  ? 346 GLN A NE2 1 
ATOM   2328 N N   . GLN A 1 347 ? 156.698 140.231 161.623 1.00 64.49  ? 347 GLN A N   1 
ATOM   2329 C CA  . GLN A 1 347 ? 158.061 139.758 161.456 1.00 64.49  ? 347 GLN A CA  1 
ATOM   2330 C C   . GLN A 1 347 ? 157.961 138.575 160.507 1.00 64.49  ? 347 GLN A C   1 
ATOM   2331 O O   . GLN A 1 347 ? 157.636 137.464 160.923 1.00 64.49  ? 347 GLN A O   1 
ATOM   2332 C CB  . GLN A 1 347 ? 158.681 139.375 162.790 1.00 64.49  ? 347 GLN A CB  1 
ATOM   2333 C CG  . GLN A 1 347 ? 160.163 139.196 162.734 1.00 64.49  ? 347 GLN A CG  1 
ATOM   2334 C CD  . GLN A 1 347 ? 160.545 137.839 162.237 1.00 64.49  ? 347 GLN A CD  1 
ATOM   2335 O OE1 . GLN A 1 347 ? 159.802 136.889 162.394 1.00 64.49  ? 347 GLN A OE1 1 
ATOM   2336 N NE2 . GLN A 1 347 ? 161.715 137.737 161.636 1.00 64.49  ? 347 GLN A NE2 1 
ATOM   2337 N N   . TYR A 1 348 ? 158.205 138.824 159.224 1.00 65.78  ? 348 TYR A N   1 
ATOM   2338 C CA  . TYR A 1 348 ? 158.023 137.826 158.183 1.00 65.78  ? 348 TYR A CA  1 
ATOM   2339 C C   . TYR A 1 348 ? 159.287 137.054 157.861 1.00 65.78  ? 348 TYR A C   1 
ATOM   2340 O O   . TYR A 1 348 ? 159.223 136.090 157.099 1.00 65.78  ? 348 TYR A O   1 
ATOM   2341 C CB  . TYR A 1 348 ? 157.504 138.494 156.912 1.00 65.78  ? 348 TYR A CB  1 
ATOM   2342 C CG  . TYR A 1 348 ? 156.203 139.221 157.112 1.00 65.78  ? 348 TYR A CG  1 
ATOM   2343 C CD1 . TYR A 1 348 ? 155.084 138.554 157.567 1.00 65.78  ? 348 TYR A CD1 1 
ATOM   2344 C CD2 . TYR A 1 348 ? 156.100 140.575 156.862 1.00 65.78  ? 348 TYR A CD2 1 
ATOM   2345 C CE1 . TYR A 1 348 ? 153.903 139.208 157.754 1.00 65.78  ? 348 TYR A CE1 1 
ATOM   2346 C CE2 . TYR A 1 348 ? 154.924 141.234 157.047 1.00 65.78  ? 348 TYR A CE2 1 
ATOM   2347 C CZ  . TYR A 1 348 ? 153.828 140.547 157.494 1.00 65.78  ? 348 TYR A CZ  1 
ATOM   2348 O OH  . TYR A 1 348 ? 152.641 141.202 157.685 1.00 65.78  ? 348 TYR A OH  1 
ATOM   2349 N N   . LYS A 1 349 ? 160.426 137.440 158.414 1.00 67.15  ? 349 LYS A N   1 
ATOM   2350 C CA  . LYS A 1 349 ? 161.678 136.740 158.166 1.00 67.15  ? 349 LYS A CA  1 
ATOM   2351 C C   . LYS A 1 349 ? 161.611 135.408 158.896 1.00 67.15  ? 349 LYS A C   1 
ATOM   2352 O O   . LYS A 1 349 ? 161.750 135.358 160.119 1.00 67.15  ? 349 LYS A O   1 
ATOM   2353 C CB  . LYS A 1 349 ? 162.859 137.582 158.634 1.00 67.15  ? 349 LYS A CB  1 
ATOM   2354 C CG  . LYS A 1 349 ? 164.212 137.046 158.257 1.00 67.15  ? 349 LYS A CG  1 
ATOM   2355 C CD  . LYS A 1 349 ? 165.235 138.155 158.246 1.00 67.15  ? 349 LYS A CD  1 
ATOM   2356 C CE  . LYS A 1 349 ? 165.736 138.466 159.624 1.00 67.15  ? 349 LYS A CE  1 
ATOM   2357 N NZ  . LYS A 1 349 ? 166.690 137.436 160.070 1.00 67.15  ? 349 LYS A NZ  1 
ATOM   2358 N N   . CYS A 1 350 ? 161.398 134.337 158.150 1.00 74.24  ? 350 CYS A N   1 
ATOM   2359 C CA  . CYS A 1 350 ? 161.131 133.018 158.709 1.00 74.24  ? 350 CYS A CA  1 
ATOM   2360 C C   . CYS A 1 350 ? 161.668 131.984 157.731 1.00 74.24  ? 350 CYS A C   1 
ATOM   2361 O O   . CYS A 1 350 ? 162.291 132.329 156.722 1.00 74.24  ? 350 CYS A O   1 
ATOM   2362 C CB  . CYS A 1 350 ? 159.640 132.816 158.944 1.00 74.24  ? 350 CYS A CB  1 
ATOM   2363 S SG  . CYS A 1 350 ? 158.716 132.874 157.408 1.00 74.24  ? 350 CYS A SG  1 
ATOM   2364 N N   . TRP A 1 351 ? 161.421 130.706 158.021 1.00 79.46  ? 351 TRP A N   1 
ATOM   2365 C CA  . TRP A 1 351 ? 161.820 129.663 157.087 1.00 79.46  ? 351 TRP A CA  1 
ATOM   2366 C C   . TRP A 1 351 ? 160.839 129.511 155.939 1.00 79.46  ? 351 TRP A C   1 
ATOM   2367 O O   . TRP A 1 351 ? 161.141 128.806 154.974 1.00 79.46  ? 351 TRP A O   1 
ATOM   2368 C CB  . TRP A 1 351 ? 161.989 128.328 157.808 1.00 79.46  ? 351 TRP A CB  1 
ATOM   2369 C CG  . TRP A 1 351 ? 160.723 127.725 158.331 1.00 79.46  ? 351 TRP A CG  1 
ATOM   2370 C CD1 . TRP A 1 351 ? 160.253 127.805 159.604 1.00 79.46  ? 351 TRP A CD1 1 
ATOM   2371 C CD2 . TRP A 1 351 ? 159.779 126.930 157.605 1.00 79.46  ? 351 TRP A CD2 1 
ATOM   2372 N NE1 . TRP A 1 351 ? 159.072 127.119 159.717 1.00 79.46  ? 351 TRP A NE1 1 
ATOM   2373 C CE2 . TRP A 1 351 ? 158.761 126.570 158.503 1.00 79.46  ? 351 TRP A CE2 1 
ATOM   2374 C CE3 . TRP A 1 351 ? 159.695 126.490 156.284 1.00 79.46  ? 351 TRP A CE3 1 
ATOM   2375 C CZ2 . TRP A 1 351 ? 157.673 125.800 158.122 1.00 79.46  ? 351 TRP A CZ2 1 
ATOM   2376 C CZ3 . TRP A 1 351 ? 158.615 125.725 155.909 1.00 79.46  ? 351 TRP A CZ3 1 
ATOM   2377 C CH2 . TRP A 1 351 ? 157.618 125.386 156.824 1.00 79.46  ? 351 TRP A CH2 1 
ATOM   2378 N N   . ILE A 1 352 ? 159.669 130.139 156.018 1.00 78.67  ? 352 ILE A N   1 
ATOM   2379 C CA  . ILE A 1 352 ? 158.719 130.121 154.917 1.00 78.67  ? 352 ILE A CA  1 
ATOM   2380 C C   . ILE A 1 352 ? 158.993 131.251 153.933 1.00 78.67  ? 352 ILE A C   1 
ATOM   2381 O O   . ILE A 1 352 ? 158.609 131.165 152.765 1.00 78.67  ? 352 ILE A O   1 
ATOM   2382 C CB  . ILE A 1 352 ? 157.267 130.179 155.425 1.00 78.67  ? 352 ILE A CB  1 
ATOM   2383 C CG1 . ILE A 1 352 ? 156.977 129.043 156.405 1.00 78.67  ? 352 ILE A CG1 1 
ATOM   2384 C CG2 . ILE A 1 352 ? 156.284 130.050 154.281 1.00 78.67  ? 352 ILE A CG2 1 
ATOM   2385 C CD1 . ILE A 1 352 ? 157.157 129.426 157.860 1.00 78.67  ? 352 ILE A CD1 1 
ATOM   2386 N N   . SER A 1 353 ? 159.677 132.302 154.375 1.00 76.85  ? 353 SER A N   1 
ATOM   2387 C CA  . SER A 1 353 ? 160.018 133.420 153.515 1.00 76.85  ? 353 SER A CA  1 
ATOM   2388 C C   . SER A 1 353 ? 161.385 133.291 152.869 1.00 76.85  ? 353 SER A C   1 
ATOM   2389 O O   . SER A 1 353 ? 161.640 133.964 151.865 1.00 76.85  ? 353 SER A O   1 
ATOM   2390 C CB  . SER A 1 353 ? 159.968 134.731 154.305 1.00 76.85  ? 353 SER A CB  1 
ATOM   2391 O OG  . SER A 1 353 ? 160.448 135.802 153.524 1.00 76.85  ? 353 SER A OG  1 
ATOM   2392 N N   . LEU A 1 354 ? 162.263 132.462 153.410 1.00 79.39  ? 354 LEU A N   1 
ATOM   2393 C CA  . LEU A 1 354 ? 163.582 132.211 152.846 1.00 79.39  ? 354 LEU A CA  1 
ATOM   2394 C C   . LEU A 1 354 ? 163.497 131.620 151.441 1.00 79.39  ? 354 LEU A C   1 
ATOM   2395 O O   . LEU A 1 354 ? 164.233 132.070 150.556 1.00 79.39  ? 354 LEU A O   1 
ATOM   2396 C CB  . LEU A 1 354 ? 164.381 131.303 153.780 1.00 79.39  ? 354 LEU A CB  1 
ATOM   2397 C CG  . LEU A 1 354 ? 165.780 130.862 153.379 1.00 79.39  ? 354 LEU A CG  1 
ATOM   2398 C CD1 . LEU A 1 354 ? 166.668 130.830 154.601 1.00 79.39  ? 354 LEU A CD1 1 
ATOM   2399 C CD2 . LEU A 1 354 ? 165.725 129.493 152.749 1.00 79.39  ? 354 LEU A CD2 1 
ATOM   2400 N N   . PRO A 1 355 ? 162.657 130.607 151.185 1.00 81.79  ? 355 PRO A N   1 
ATOM   2401 C CA  . PRO A 1 355 ? 162.520 130.141 149.796 1.00 81.79  ? 355 PRO A CA  1 
ATOM   2402 C C   . PRO A 1 355 ? 162.041 131.219 148.848 1.00 81.79  ? 355 PRO A C   1 
ATOM   2403 O O   . PRO A 1 355 ? 162.557 131.331 147.733 1.00 81.79  ? 355 PRO A O   1 
ATOM   2404 C CB  . PRO A 1 355 ? 161.506 129.001 149.913 1.00 81.79  ? 355 PRO A CB  1 
ATOM   2405 C CG  . PRO A 1 355 ? 161.640 128.529 151.281 1.00 81.79  ? 355 PRO A CG  1 
ATOM   2406 C CD  . PRO A 1 355 ? 161.897 129.743 152.100 1.00 81.79  ? 355 PRO A CD  1 
ATOM   2407 N N   . ILE A 1 356 ? 161.065 132.024 149.263 1.00 84.40  ? 356 ILE A N   1 
ATOM   2408 C CA  . ILE A 1 356 ? 160.555 133.065 148.381 1.00 84.40  ? 356 ILE A CA  1 
ATOM   2409 C C   . ILE A 1 356 ? 161.649 134.068 148.068 1.00 84.40  ? 356 ILE A C   1 
ATOM   2410 O O   . ILE A 1 356 ? 161.848 134.450 146.910 1.00 84.40  ? 356 ILE A O   1 
ATOM   2411 C CB  . ILE A 1 356 ? 159.329 133.748 149.006 1.00 84.40  ? 356 ILE A CB  1 
ATOM   2412 C CG1 . ILE A 1 356 ? 158.209 132.735 149.211 1.00 84.40  ? 356 ILE A CG1 1 
ATOM   2413 C CG2 . ILE A 1 356 ? 158.853 134.876 148.126 1.00 84.40  ? 356 ILE A CG2 1 
ATOM   2414 C CD1 . ILE A 1 356 ? 157.078 133.258 150.049 1.00 84.40  ? 356 ILE A CD1 1 
ATOM   2415 N N   . VAL A 1 357 ? 162.393 134.494 149.087 1.00 82.12  ? 357 VAL A N   1 
ATOM   2416 C CA  . VAL A 1 357 ? 163.467 135.455 148.861 1.00 82.12  ? 357 VAL A CA  1 
ATOM   2417 C C   . VAL A 1 357 ? 164.522 134.871 147.936 1.00 82.12  ? 357 VAL A C   1 
ATOM   2418 O O   . VAL A 1 357 ? 164.930 135.505 146.954 1.00 82.12  ? 357 VAL A O   1 
ATOM   2419 C CB  . VAL A 1 357 ? 164.077 135.889 150.201 1.00 82.12  ? 357 VAL A CB  1 
ATOM   2420 C CG1 . VAL A 1 357 ? 165.396 136.573 149.971 1.00 82.12  ? 357 VAL A CG1 1 
ATOM   2421 C CG2 . VAL A 1 357 ? 163.127 136.804 150.921 1.00 82.12  ? 357 VAL A CG2 1 
ATOM   2422 N N   . PHE A 1 358 ? 164.974 133.651 148.222 1.00 83.58  ? 358 PHE A N   1 
ATOM   2423 C CA  . PHE A 1 358 ? 166.043 133.062 147.428 1.00 83.58  ? 358 PHE A CA  1 
ATOM   2424 C C   . PHE A 1 358 ? 165.613 132.862 145.985 1.00 83.58  ? 358 PHE A C   1 
ATOM   2425 O O   . PHE A 1 358 ? 166.367 133.181 145.066 1.00 83.58  ? 358 PHE A O   1 
ATOM   2426 C CB  . PHE A 1 358 ? 166.485 131.741 148.053 1.00 83.58  ? 358 PHE A CB  1 
ATOM   2427 C CG  . PHE A 1 358 ? 167.529 131.014 147.265 1.00 83.58  ? 358 PHE A CG  1 
ATOM   2428 C CD1 . PHE A 1 358 ? 168.863 131.194 147.543 1.00 83.58  ? 358 PHE A CD1 1 
ATOM   2429 C CD2 . PHE A 1 358 ? 167.176 130.127 146.268 1.00 83.58  ? 358 PHE A CD2 1 
ATOM   2430 C CE1 . PHE A 1 358 ? 169.828 130.521 146.838 1.00 83.58  ? 358 PHE A CE1 1 
ATOM   2431 C CE2 . PHE A 1 358 ? 168.140 129.454 145.553 1.00 83.58  ? 358 PHE A CE2 1 
ATOM   2432 C CZ  . PHE A 1 358 ? 169.467 129.649 145.841 1.00 83.58  ? 358 PHE A CZ  1 
ATOM   2433 N N   . VAL A 1 359 ? 164.405 132.345 145.763 1.00 85.43  ? 359 VAL A N   1 
ATOM   2434 C CA  . VAL A 1 359 ? 163.931 132.122 144.403 1.00 85.43  ? 359 VAL A CA  1 
ATOM   2435 C C   . VAL A 1 359 ? 163.774 133.443 143.667 1.00 85.43  ? 359 VAL A C   1 
ATOM   2436 O O   . VAL A 1 359 ? 164.170 133.578 142.504 1.00 85.43  ? 359 VAL A O   1 
ATOM   2437 C CB  . VAL A 1 359 ? 162.612 131.333 144.423 1.00 85.43  ? 359 VAL A CB  1 
ATOM   2438 C CG1 . VAL A 1 359 ? 161.945 131.390 143.066 1.00 85.43  ? 359 VAL A CG1 1 
ATOM   2439 C CG2 . VAL A 1 359 ? 162.870 129.900 144.835 1.00 85.43  ? 359 VAL A CG2 1 
ATOM   2440 N N   . LEU A 1 360 ? 163.204 134.443 144.332 1.00 87.33  ? 360 LEU A N   1 
ATOM   2441 C CA  . LEU A 1 360 ? 162.872 135.674 143.637 1.00 87.33  ? 360 LEU A CA  1 
ATOM   2442 C C   . LEU A 1 360 ? 164.097 136.566 143.453 1.00 87.33  ? 360 LEU A C   1 
ATOM   2443 O O   . LEU A 1 360 ? 164.040 137.535 142.691 1.00 87.33  ? 360 LEU A O   1 
ATOM   2444 C CB  . LEU A 1 360 ? 161.731 136.355 144.393 1.00 87.33  ? 360 LEU A CB  1 
ATOM   2445 C CG  . LEU A 1 360 ? 160.984 137.583 143.899 1.00 87.33  ? 360 LEU A CG  1 
ATOM   2446 C CD1 . LEU A 1 360 ? 159.597 137.565 144.485 1.00 87.33  ? 360 LEU A CD1 1 
ATOM   2447 C CD2 . LEU A 1 360 ? 161.683 138.798 144.404 1.00 87.33  ? 360 LEU A CD2 1 
ATOM   2448 N N   . ILE A 1 361 ? 165.212 136.255 144.118 1.00 88.84  ? 361 ILE A N   1 
ATOM   2449 C CA  . ILE A 1 361 ? 166.473 136.901 143.748 1.00 88.84  ? 361 ILE A CA  1 
ATOM   2450 C C   . ILE A 1 361 ? 167.242 136.052 142.738 1.00 88.84  ? 361 ILE A C   1 
ATOM   2451 O O   . ILE A 1 361 ? 167.941 136.588 141.864 1.00 88.84  ? 361 ILE A O   1 
ATOM   2452 C CB  . ILE A 1 361 ? 167.334 137.196 144.987 1.00 88.84  ? 361 ILE A CB  1 
ATOM   2453 C CG1 . ILE A 1 361 ? 166.546 138.003 146.008 1.00 88.84  ? 361 ILE A CG1 1 
ATOM   2454 C CG2 . ILE A 1 361 ? 168.576 137.977 144.593 1.00 88.84  ? 361 ILE A CG2 1 
ATOM   2455 C CD1 . ILE A 1 361 ? 166.189 139.370 145.524 1.00 88.84  ? 361 ILE A CD1 1 
ATOM   2456 N N   . GLY A 1 362 ? 167.130 134.727 142.823 1.00 93.57  ? 362 GLY A N   1 
ATOM   2457 C CA  . GLY A 1 362 ? 167.711 133.881 141.802 1.00 93.57  ? 362 GLY A CA  1 
ATOM   2458 C C   . GLY A 1 362 ? 167.103 134.127 140.442 1.00 93.57  ? 362 GLY A C   1 
ATOM   2459 O O   . GLY A 1 362 ? 167.720 133.829 139.422 1.00 93.57  ? 362 GLY A O   1 
ATOM   2460 N N   . ALA A 1 363 ? 165.892 134.672 140.403 1.00 92.23  ? 363 ALA A N   1 
ATOM   2461 C CA  . ALA A 1 363 ? 165.320 135.092 139.132 1.00 92.23  ? 363 ALA A CA  1 
ATOM   2462 C C   . ALA A 1 363 ? 166.221 136.125 138.465 1.00 92.23  ? 363 ALA A C   1 
ATOM   2463 O O   . ALA A 1 363 ? 166.630 135.957 137.306 1.00 92.23  ? 363 ALA A O   1 
ATOM   2464 C CB  . ALA A 1 363 ? 163.919 135.661 139.342 1.00 92.23  ? 363 ALA A CB  1 
ATOM   2465 N N   . LEU A 1 364 ? 166.553 137.185 139.201 1.00 93.34  ? 364 LEU A N   1 
ATOM   2466 C CA  . LEU A 1 364 ? 167.466 138.189 138.673 1.00 93.34  ? 364 LEU A CA  1 
ATOM   2467 C C   . LEU A 1 364 ? 168.815 137.572 138.361 1.00 93.34  ? 364 LEU A C   1 
ATOM   2468 O O   . LEU A 1 364 ? 169.470 137.949 137.385 1.00 93.34  ? 364 LEU A O   1 
ATOM   2469 C CB  . LEU A 1 364 ? 167.632 139.344 139.662 1.00 93.34  ? 364 LEU A CB  1 
ATOM   2470 C CG  . LEU A 1 364 ? 166.606 140.478 139.705 1.00 93.34  ? 364 LEU A CG  1 
ATOM   2471 C CD1 . LEU A 1 364 ? 166.596 141.244 138.400 1.00 93.34  ? 364 LEU A CD1 1 
ATOM   2472 C CD2 . LEU A 1 364 ? 165.221 139.965 140.028 1.00 93.34  ? 364 LEU A CD2 1 
ATOM   2473 N N   . GLN A 1 365 ? 169.253 136.623 139.186 1.00 95.22  ? 365 GLN A N   1 
ATOM   2474 C CA  . GLN A 1 365 ? 170.557 136.014 138.946 1.00 95.22  ? 365 GLN A CA  1 
ATOM   2475 C C   . GLN A 1 365 ? 170.585 135.256 137.623 1.00 95.22  ? 365 GLN A C   1 
ATOM   2476 O O   . GLN A 1 365 ? 171.549 135.368 136.858 1.00 95.22  ? 365 GLN A O   1 
ATOM   2477 C CB  . GLN A 1 365 ? 170.928 135.088 140.094 1.00 95.22  ? 365 GLN A CB  1 
ATOM   2478 C CG  . GLN A 1 365 ? 172.294 134.486 139.925 1.00 95.22  ? 365 GLN A CG  1 
ATOM   2479 C CD  . GLN A 1 365 ? 173.293 135.498 139.424 1.00 95.22  ? 365 GLN A CD  1 
ATOM   2480 O OE1 . GLN A 1 365 ? 173.468 136.560 140.015 1.00 95.22  ? 365 GLN A OE1 1 
ATOM   2481 N NE2 . GLN A 1 365 ? 173.953 135.176 138.326 1.00 95.22  ? 365 GLN A NE2 1 
ATOM   2482 N N   . LEU A 1 366 ? 169.543 134.476 137.336 1.00 98.05  ? 366 LEU A N   1 
ATOM   2483 C CA  . LEU A 1 366 ? 169.483 133.747 136.073 1.00 98.05  ? 366 LEU A CA  1 
ATOM   2484 C C   . LEU A 1 366 ? 169.376 134.697 134.889 1.00 98.05  ? 366 LEU A C   1 
ATOM   2485 O O   . LEU A 1 366 ? 170.008 134.477 133.847 1.00 98.05  ? 366 LEU A O   1 
ATOM   2486 C CB  . LEU A 1 366 ? 168.318 132.757 136.076 1.00 98.05  ? 366 LEU A CB  1 
ATOM   2487 C CG  . LEU A 1 366 ? 168.517 131.357 136.666 1.00 98.05  ? 366 LEU A CG  1 
ATOM   2488 C CD1 . LEU A 1 366 ? 169.523 130.608 135.829 1.00 98.05  ? 366 LEU A CD1 1 
ATOM   2489 C CD2 . LEU A 1 366 ? 168.975 131.380 138.103 1.00 98.05  ? 366 LEU A CD2 1 
ATOM   2490 N N   . VAL A 1 367 ? 168.565 135.749 135.017 1.00 98.13  ? 367 VAL A N   1 
ATOM   2491 C CA  . VAL A 1 367 ? 168.503 136.730 133.938 1.00 98.13  ? 367 VAL A CA  1 
ATOM   2492 C C   . VAL A 1 367 ? 169.866 137.353 133.685 1.00 98.13  ? 367 VAL A C   1 
ATOM   2493 O O   . VAL A 1 367 ? 170.259 137.559 132.527 1.00 98.13  ? 367 VAL A O   1 
ATOM   2494 C CB  . VAL A 1 367 ? 167.459 137.809 134.256 1.00 98.13  ? 367 VAL A CB  1 
ATOM   2495 C CG1 . VAL A 1 367 ? 167.502 138.906 133.219 1.00 98.13  ? 367 VAL A CG1 1 
ATOM   2496 C CG2 . VAL A 1 367 ? 166.091 137.191 134.321 1.00 98.13  ? 367 VAL A CG2 1 
ATOM   2497 N N   . ASN A 1 368 ? 170.607 137.643 134.751 1.00 98.02  ? 368 ASN A N   1 
ATOM   2498 C CA  . ASN A 1 368 ? 171.946 138.186 134.603 1.00 98.02  ? 368 ASN A CA  1 
ATOM   2499 C C   . ASN A 1 368 ? 172.871 137.186 133.927 1.00 98.02  ? 368 ASN A C   1 
ATOM   2500 O O   . ASN A 1 368 ? 173.721 137.568 133.122 1.00 98.02  ? 368 ASN A O   1 
ATOM   2501 C CB  . ASN A 1 368 ? 172.482 138.583 135.971 1.00 98.02  ? 368 ASN A CB  1 
ATOM   2502 C CG  . ASN A 1 368 ? 171.928 139.899 136.442 1.00 98.02  ? 368 ASN A CG  1 
ATOM   2503 O OD1 . ASN A 1 368 ? 170.871 140.335 135.989 1.00 98.02  ? 368 ASN A OD1 1 
ATOM   2504 N ND2 . ASN A 1 368 ? 172.622 140.534 137.371 1.00 98.02  ? 368 ASN A ND2 1 
ATOM   2505 N N   . LEU A 1 369 ? 172.724 135.900 134.248 1.00 100.84 ? 369 LEU A N   1 
ATOM   2506 C CA  . LEU A 1 369 ? 173.525 134.875 133.587 1.00 100.84 ? 369 LEU A CA  1 
ATOM   2507 C C   . LEU A 1 369 ? 173.254 134.844 132.091 1.00 100.84 ? 369 LEU A C   1 
ATOM   2508 O O   . LEU A 1 369 ? 174.181 134.733 131.281 1.00 100.84 ? 369 LEU A O   1 
ATOM   2509 C CB  . LEU A 1 369 ? 173.241 133.507 134.199 1.00 100.84 ? 369 LEU A CB  1 
ATOM   2510 C CG  . LEU A 1 369 ? 173.646 133.253 135.645 1.00 100.84 ? 369 LEU A CG  1 
ATOM   2511 C CD1 . LEU A 1 369 ? 173.142 131.897 136.079 1.00 100.84 ? 369 LEU A CD1 1 
ATOM   2512 C CD2 . LEU A 1 369 ? 175.149 133.313 135.773 1.00 100.84 ? 369 LEU A CD2 1 
ATOM   2513 N N   . TYR A 1 370 ? 171.981 134.919 131.707 1.00 106.27 ? 370 TYR A N   1 
ATOM   2514 C CA  . TYR A 1 370 ? 171.626 134.909 130.289 1.00 106.27 ? 370 TYR A CA  1 
ATOM   2515 C C   . TYR A 1 370 ? 172.214 136.114 129.565 1.00 106.27 ? 370 TYR A C   1 
ATOM   2516 O O   . TYR A 1 370 ? 172.804 135.990 128.478 1.00 106.27 ? 370 TYR A O   1 
ATOM   2517 C CB  . TYR A 1 370 ? 170.105 134.876 130.147 1.00 106.27 ? 370 TYR A CB  1 
ATOM   2518 C CG  . TYR A 1 370 ? 169.594 135.111 128.749 1.00 106.27 ? 370 TYR A CG  1 
ATOM   2519 C CD1 . TYR A 1 370 ? 168.564 136.007 128.516 1.00 106.27 ? 370 TYR A CD1 1 
ATOM   2520 C CD2 . TYR A 1 370 ? 170.128 134.433 127.665 1.00 106.27 ? 370 TYR A CD2 1 
ATOM   2521 C CE1 . TYR A 1 370 ? 168.085 136.227 127.246 1.00 106.27 ? 370 TYR A CE1 1 
ATOM   2522 C CE2 . TYR A 1 370 ? 169.655 134.649 126.388 1.00 106.27 ? 370 TYR A CE2 1 
ATOM   2523 C CZ  . TYR A 1 370 ? 168.634 135.548 126.186 1.00 106.27 ? 370 TYR A CZ  1 
ATOM   2524 O OH  . TYR A 1 370 ? 168.154 135.771 124.920 1.00 106.27 ? 370 TYR A OH  1 
ATOM   2525 N N   . TRP A 1 371 ? 172.073 137.280 130.190 1.00 108.18 ? 371 TRP A N   1 
ATOM   2526 C CA  . TRP A 1 371 ? 172.607 138.513 129.635 1.00 108.18 ? 371 TRP A CA  1 
ATOM   2527 C C   . TRP A 1 371 ? 174.113 138.367 129.467 1.00 108.18 ? 371 TRP A C   1 
ATOM   2528 O O   . TRP A 1 371 ? 174.674 138.769 128.448 1.00 108.18 ? 371 TRP A O   1 
ATOM   2529 C CB  . TRP A 1 371 ? 172.286 139.699 130.544 1.00 108.18 ? 371 TRP A CB  1 
ATOM   2530 C CG  . TRP A 1 371 ? 171.340 140.684 129.930 1.00 108.18 ? 371 TRP A CG  1 
ATOM   2531 C CD1 . TRP A 1 371 ? 171.589 141.512 128.873 1.00 108.18 ? 371 TRP A CD1 1 
ATOM   2532 C CD2 . TRP A 1 371 ? 169.990 140.946 130.333 1.00 108.18 ? 371 TRP A CD2 1 
ATOM   2533 N NE1 . TRP A 1 371 ? 170.479 142.272 128.595 1.00 108.18 ? 371 TRP A NE1 1 
ATOM   2534 C CE2 . TRP A 1 371 ? 169.484 141.944 129.477 1.00 108.18 ? 371 TRP A CE2 1 
ATOM   2535 C CE3 . TRP A 1 371 ? 169.161 140.433 131.336 1.00 108.18 ? 371 TRP A CE3 1 
ATOM   2536 C CZ2 . TRP A 1 371 ? 168.187 142.439 129.592 1.00 108.18 ? 371 TRP A CZ2 1 
ATOM   2537 C CZ3 . TRP A 1 371 ? 167.873 140.926 131.448 1.00 108.18 ? 371 TRP A CZ3 1 
ATOM   2538 C CH2 . TRP A 1 371 ? 167.399 141.919 130.581 1.00 108.18 ? 371 TRP A CH2 1 
ATOM   2539 N N   . LEU A 1 372 ? 174.767 137.787 130.471 1.00 108.40 ? 372 LEU A N   1 
ATOM   2540 C CA  . LEU A 1 372 ? 176.207 137.580 130.399 1.00 108.40 ? 372 LEU A CA  1 
ATOM   2541 C C   . LEU A 1 372 ? 176.578 136.651 129.254 1.00 108.40 ? 372 LEU A C   1 
ATOM   2542 O O   . LEU A 1 372 ? 177.592 136.862 128.582 1.00 108.40 ? 372 LEU A O   1 
ATOM   2543 C CB  . LEU A 1 372 ? 176.737 137.023 131.717 1.00 108.40 ? 372 LEU A CB  1 
ATOM   2544 C CG  . LEU A 1 372 ? 178.254 136.861 131.725 1.00 108.40 ? 372 LEU A CG  1 
ATOM   2545 C CD1 . LEU A 1 372 ? 178.910 138.177 131.365 1.00 108.40 ? 372 LEU A CD1 1 
ATOM   2546 C CD2 . LEU A 1 372 ? 178.736 136.377 133.073 1.00 108.40 ? 372 LEU A CD2 1 
ATOM   2547 N N   . PHE A 1 373 ? 175.787 135.601 129.032 1.00 113.98 ? 373 PHE A N   1 
ATOM   2548 C CA  . PHE A 1 373 ? 176.062 134.704 127.912 1.00 113.98 ? 373 PHE A CA  1 
ATOM   2549 C C   . PHE A 1 373 ? 176.051 135.470 126.601 1.00 113.98 ? 373 PHE A C   1 
ATOM   2550 O O   . PHE A 1 373 ? 176.974 135.350 125.783 1.00 113.98 ? 373 PHE A O   1 
ATOM   2551 C CB  . PHE A 1 373 ? 175.041 133.567 127.861 1.00 113.98 ? 373 PHE A CB  1 
ATOM   2552 C CG  . PHE A 1 373 ? 175.227 132.528 128.929 1.00 113.98 ? 373 PHE A CG  1 
ATOM   2553 C CD1 . PHE A 1 373 ? 174.186 131.682 129.273 1.00 113.98 ? 373 PHE A CD1 1 
ATOM   2554 C CD2 . PHE A 1 373 ? 176.438 132.395 129.586 1.00 113.98 ? 373 PHE A CD2 1 
ATOM   2555 C CE1 . PHE A 1 373 ? 174.346 130.728 130.254 1.00 113.98 ? 373 PHE A CE1 1 
ATOM   2556 C CE2 . PHE A 1 373 ? 176.604 131.442 130.568 1.00 113.98 ? 373 PHE A CE2 1 
ATOM   2557 C CZ  . PHE A 1 373 ? 175.556 130.607 130.903 1.00 113.98 ? 373 PHE A CZ  1 
ATOM   2558 N N   . LEU A 1 374 ? 175.018 136.285 126.389 1.00 115.11 ? 374 LEU A N   1 
ATOM   2559 C CA  . LEU A 1 374 ? 174.978 137.010 125.125 1.00 115.11 ? 374 LEU A CA  1 
ATOM   2560 C C   . LEU A 1 374 ? 176.036 138.109 125.060 1.00 115.11 ? 374 LEU A C   1 
ATOM   2561 O O   . LEU A 1 374 ? 176.542 138.394 123.969 1.00 115.11 ? 374 LEU A O   1 
ATOM   2562 C CB  . LEU A 1 374 ? 173.583 137.573 124.851 1.00 115.11 ? 374 LEU A CB  1 
ATOM   2563 C CG  . LEU A 1 374 ? 172.979 138.759 125.587 1.00 115.11 ? 374 LEU A CG  1 
ATOM   2564 C CD1 . LEU A 1 374 ? 173.347 140.055 124.888 1.00 115.11 ? 374 LEU A CD1 1 
ATOM   2565 C CD2 . LEU A 1 374 ? 171.476 138.592 125.616 1.00 115.11 ? 374 LEU A CD2 1 
ATOM   2566 N N   . ILE A 1 375 ? 176.428 138.650 126.209 1.00 118.89 ? 375 ILE A N   1 
ATOM   2567 C CA  . ILE A 1 375 ? 177.475 139.661 126.245 1.00 118.89 ? 375 ILE A CA  1 
ATOM   2568 C C   . ILE A 1 375 ? 178.790 139.000 125.827 1.00 118.89 ? 375 ILE A C   1 
ATOM   2569 O O   . ILE A 1 375 ? 179.600 139.596 125.117 1.00 118.89 ? 375 ILE A O   1 
ATOM   2570 C CB  . ILE A 1 375 ? 177.633 140.269 127.649 1.00 118.89 ? 375 ILE A CB  1 
ATOM   2571 C CG1 . ILE A 1 375 ? 178.513 141.520 127.593 1.00 118.89 ? 375 ILE A CG1 1 
ATOM   2572 C CG2 . ILE A 1 375 ? 178.216 139.246 128.611 1.00 118.89 ? 375 ILE A CG2 1 
ATOM   2573 C CD1 . ILE A 1 375 ? 179.956 141.235 127.240 1.00 118.89 ? 375 ILE A CD1 1 
ATOM   2574 N N   . PHE A 1 376 ? 178.987 137.764 126.278 1.00 126.17 ? 376 PHE A N   1 
ATOM   2575 C CA  . PHE A 1 376 ? 180.172 136.985 125.954 1.00 126.17 ? 376 PHE A CA  1 
ATOM   2576 C C   . PHE A 1 376 ? 180.187 136.788 124.445 1.00 126.17 ? 376 PHE A C   1 
ATOM   2577 O O   . PHE A 1 376 ? 181.191 137.050 123.782 1.00 126.17 ? 376 PHE A O   1 
ATOM   2578 C CB  . PHE A 1 376 ? 180.143 135.634 126.668 1.00 126.17 ? 376 PHE A CB  1 
ATOM   2579 C CG  . PHE A 1 376 ? 181.505 135.088 126.990 1.00 126.17 ? 376 PHE A CG  1 
ATOM   2580 C CD1 . PHE A 1 376 ? 181.920 134.953 128.305 1.00 126.17 ? 376 PHE A CD1 1 
ATOM   2581 C CD2 . PHE A 1 376 ? 182.372 134.710 125.978 1.00 126.17 ? 376 PHE A CD2 1 
ATOM   2582 C CE1 . PHE A 1 376 ? 183.172 134.452 128.604 1.00 126.17 ? 376 PHE A CE1 1 
ATOM   2583 C CE2 . PHE A 1 376 ? 183.626 134.207 126.270 1.00 126.17 ? 376 PHE A CE2 1 
ATOM   2584 C CZ  . PHE A 1 376 ? 184.026 134.079 127.586 1.00 126.17 ? 376 PHE A CZ  1 
ATOM   2585 N N   . ARG A 1 377 ? 179.054 136.349 123.906 1.00 128.35 ? 377 ARG A N   1 
ATOM   2586 C CA  . ARG A 1 377 ? 178.924 136.132 122.471 1.00 128.35 ? 377 ARG A CA  1 
ATOM   2587 C C   . ARG A 1 377 ? 179.333 137.384 121.704 1.00 128.35 ? 377 ARG A C   1 
ATOM   2588 O O   . ARG A 1 377 ? 180.093 137.310 120.737 1.00 128.35 ? 377 ARG A O   1 
ATOM   2589 C CB  . ARG A 1 377 ? 177.489 135.740 122.115 1.00 128.35 ? 377 ARG A CB  1 
ATOM   2590 C CG  . ARG A 1 377 ? 177.237 135.599 120.623 1.00 128.35 ? 377 ARG A CG  1 
ATOM   2591 C CD  . ARG A 1 377 ? 175.992 134.771 120.349 1.00 128.35 ? 377 ARG A CD  1 
ATOM   2592 N NE  . ARG A 1 377 ? 174.934 135.037 121.319 1.00 128.35 ? 377 ARG A NE  1 
ATOM   2593 C CZ  . ARG A 1 377 ? 173.674 135.308 120.995 1.00 128.35 ? 377 ARG A CZ  1 
ATOM   2594 N NH1 . ARG A 1 377 ? 172.778 135.538 121.945 1.00 128.35 ? 377 ARG A NH1 1 
ATOM   2595 N NH2 . ARG A 1 377 ? 173.309 135.348 119.721 1.00 128.35 ? 377 ARG A NH2 1 
ATOM   2596 N N   . VAL A 1 378 ? 178.826 138.535 122.137 1.00 129.53 ? 378 VAL A N   1 
ATOM   2597 C CA  . VAL A 1 378 ? 179.152 139.801 121.485 1.00 129.53 ? 378 VAL A CA  1 
ATOM   2598 C C   . VAL A 1 378 ? 180.651 140.059 121.558 1.00 129.53 ? 378 VAL A C   1 
ATOM   2599 O O   . VAL A 1 378 ? 181.277 140.498 120.586 1.00 129.53 ? 378 VAL A O   1 
ATOM   2600 C CB  . VAL A 1 378 ? 178.352 140.950 122.124 1.00 129.53 ? 378 VAL A CB  1 
ATOM   2601 C CG1 . VAL A 1 378 ? 178.950 142.298 121.757 1.00 129.53 ? 378 VAL A CG1 1 
ATOM   2602 C CG2 . VAL A 1 378 ? 176.892 140.875 121.709 1.00 129.53 ? 378 VAL A CG2 1 
ATOM   2603 N N   . LEU A 1 379 ? 181.242 139.799 122.723 1.00 133.38 ? 379 LEU A N   1 
ATOM   2604 C CA  . LEU A 1 379 ? 182.667 140.029 122.916 1.00 133.38 ? 379 LEU A CA  1 
ATOM   2605 C C   . LEU A 1 379 ? 183.484 139.176 121.961 1.00 133.38 ? 379 LEU A C   1 
ATOM   2606 O O   . LEU A 1 379 ? 184.421 139.659 121.320 1.00 133.38 ? 379 LEU A O   1 
ATOM   2607 C CB  . LEU A 1 379 ? 183.053 139.725 124.362 1.00 133.38 ? 379 LEU A CB  1 
ATOM   2608 C CG  . LEU A 1 379 ? 184.513 139.983 124.730 1.00 133.38 ? 379 LEU A CG  1 
ATOM   2609 C CD1 . LEU A 1 379 ? 184.864 141.454 124.581 1.00 133.38 ? 379 LEU A CD1 1 
ATOM   2610 C CD2 . LEU A 1 379 ? 184.806 139.489 126.135 1.00 133.38 ? 379 LEU A CD2 1 
ATOM   2611 N N   . TYR A 1 380 ? 183.126 137.896 121.848 1.00 139.17 ? 380 TYR A N   1 
ATOM   2612 C CA  . TYR A 1 380 ? 183.809 136.998 120.922 1.00 139.17 ? 380 TYR A CA  1 
ATOM   2613 C C   . TYR A 1 380 ? 183.727 137.506 119.489 1.00 139.17 ? 380 TYR A C   1 
ATOM   2614 O O   . TYR A 1 380 ? 184.746 137.616 118.792 1.00 139.17 ? 380 TYR A O   1 
ATOM   2615 C CB  . TYR A 1 380 ? 183.199 135.600 121.024 1.00 139.17 ? 380 TYR A CB  1 
ATOM   2616 C CG  . TYR A 1 380 ? 183.579 134.671 119.897 1.00 139.17 ? 380 TYR A CG  1 
ATOM   2617 C CD1 . TYR A 1 380 ? 184.855 134.137 119.807 1.00 139.17 ? 380 TYR A CD1 1 
ATOM   2618 C CD2 . TYR A 1 380 ? 182.654 134.328 118.920 1.00 139.17 ? 380 TYR A CD2 1 
ATOM   2619 C CE1 . TYR A 1 380 ? 185.199 133.282 118.779 1.00 139.17 ? 380 TYR A CE1 1 
ATOM   2620 C CE2 . TYR A 1 380 ? 182.988 133.476 117.887 1.00 139.17 ? 380 TYR A CE2 1 
ATOM   2621 C CZ  . TYR A 1 380 ? 184.262 132.958 117.820 1.00 139.17 ? 380 TYR A CZ  1 
ATOM   2622 O OH  . TYR A 1 380 ? 184.601 132.109 116.791 1.00 139.17 ? 380 TYR A OH  1 
ATOM   2623 N N   . ARG A 1 381 ? 182.515 137.827 119.034 1.00 139.51 ? 381 ARG A N   1 
ATOM   2624 C CA  . ARG A 1 381 ? 182.357 138.238 117.643 1.00 139.51 ? 381 ARG A CA  1 
ATOM   2625 C C   . ARG A 1 381 ? 183.076 139.549 117.345 1.00 139.51 ? 381 ARG A C   1 
ATOM   2626 O O   . ARG A 1 381 ? 183.701 139.676 116.288 1.00 139.51 ? 381 ARG A O   1 
ATOM   2627 C CB  . ARG A 1 381 ? 180.875 138.328 117.286 1.00 139.51 ? 381 ARG A CB  1 
ATOM   2628 C CG  . ARG A 1 381 ? 180.208 136.966 117.263 1.00 139.51 ? 381 ARG A CG  1 
ATOM   2629 C CD  . ARG A 1 381 ? 178.738 137.037 116.906 1.00 139.51 ? 381 ARG A CD  1 
ATOM   2630 N NE  . ARG A 1 381 ? 178.138 135.706 116.913 1.00 139.51 ? 381 ARG A NE  1 
ATOM   2631 C CZ  . ARG A 1 381 ? 176.852 135.461 116.690 1.00 139.51 ? 381 ARG A CZ  1 
ATOM   2632 N NH1 . ARG A 1 381 ? 176.015 136.458 116.446 1.00 139.51 ? 381 ARG A NH1 1 
ATOM   2633 N NH2 . ARG A 1 381 ? 176.401 134.214 116.715 1.00 139.51 ? 381 ARG A NH2 1 
ATOM   2634 N N   . ILE A 1 382 ? 183.016 140.527 118.251 1.00 141.63 ? 382 ILE A N   1 
ATOM   2635 C CA  . ILE A 1 382 ? 183.735 141.776 118.009 1.00 141.63 ? 382 ILE A CA  1 
ATOM   2636 C C   . ILE A 1 382 ? 185.242 141.561 118.107 1.00 141.63 ? 382 ILE A C   1 
ATOM   2637 O O   . ILE A 1 382 ? 186.017 142.234 117.417 1.00 141.63 ? 382 ILE A O   1 
ATOM   2638 C CB  . ILE A 1 382 ? 183.226 142.879 118.960 1.00 141.63 ? 382 ILE A CB  1 
ATOM   2639 C CG1 . ILE A 1 382 ? 181.868 143.399 118.474 1.00 141.63 ? 382 ILE A CG1 1 
ATOM   2640 C CG2 . ILE A 1 382 ? 184.217 144.029 119.068 1.00 141.63 ? 382 ILE A CG2 1 
ATOM   2641 C CD1 . ILE A 1 382 ? 181.223 144.411 119.392 1.00 141.63 ? 382 ILE A CD1 1 
ATOM   2642 N N   . LEU A 1 383 ? 185.683 140.609 118.934 1.00 141.73 ? 383 LEU A N   1 
ATOM   2643 C CA  . LEU A 1 383 ? 187.099 140.263 118.989 1.00 141.73 ? 383 LEU A CA  1 
ATOM   2644 C C   . LEU A 1 383 ? 187.583 139.682 117.668 1.00 141.73 ? 383 LEU A C   1 
ATOM   2645 O O   . LEU A 1 383 ? 188.700 139.982 117.232 1.00 141.73 ? 383 LEU A O   1 
ATOM   2646 C CB  . LEU A 1 383 ? 187.343 139.278 120.136 1.00 141.73 ? 383 LEU A CB  1 
ATOM   2647 C CG  . LEU A 1 383 ? 188.771 138.883 120.526 1.00 141.73 ? 383 LEU A CG  1 
ATOM   2648 C CD1 . LEU A 1 383 ? 188.810 138.487 121.989 1.00 141.73 ? 383 LEU A CD1 1 
ATOM   2649 C CD2 . LEU A 1 383 ? 189.299 137.738 119.671 1.00 141.73 ? 383 LEU A CD2 1 
ATOM   2650 N N   . TRP A 1 384 ? 186.768 138.851 117.021 1.00 143.51 ? 384 TRP A N   1 
ATOM   2651 C CA  . TRP A 1 384 ? 187.133 138.274 115.734 1.00 143.51 ? 384 TRP A CA  1 
ATOM   2652 C C   . TRP A 1 384 ? 186.608 139.094 114.559 1.00 143.51 ? 384 TRP A C   1 
ATOM   2653 O O   . TRP A 1 384 ? 186.310 138.531 113.500 1.00 143.51 ? 384 TRP A O   1 
ATOM   2654 C CB  . TRP A 1 384 ? 186.648 136.828 115.643 1.00 143.51 ? 384 TRP A CB  1 
ATOM   2655 C CG  . TRP A 1 384 ? 187.593 135.872 116.294 1.00 143.51 ? 384 TRP A CG  1 
ATOM   2656 C CD1 . TRP A 1 384 ? 187.422 135.236 117.484 1.00 143.51 ? 384 TRP A CD1 1 
ATOM   2657 C CD2 . TRP A 1 384 ? 188.874 135.464 115.801 1.00 143.51 ? 384 TRP A CD2 1 
ATOM   2658 N NE1 . TRP A 1 384 ? 188.509 134.446 117.761 1.00 143.51 ? 384 TRP A NE1 1 
ATOM   2659 C CE2 . TRP A 1 384 ? 189.418 134.569 116.743 1.00 143.51 ? 384 TRP A CE2 1 
ATOM   2660 C CE3 . TRP A 1 384 ? 189.613 135.765 114.652 1.00 143.51 ? 384 TRP A CE3 1 
ATOM   2661 C CZ2 . TRP A 1 384 ? 190.664 133.971 116.573 1.00 143.51 ? 384 TRP A CZ2 1 
ATOM   2662 C CZ3 . TRP A 1 384 ? 190.851 135.170 114.484 1.00 143.51 ? 384 TRP A CZ3 1 
ATOM   2663 C CH2 . TRP A 1 384 ? 191.364 134.283 115.440 1.00 143.51 ? 384 TRP A CH2 1 
ATOM   2664 N N   . ARG A 1 385 ? 186.492 140.407 114.728 1.00 141.48 ? 385 ARG A N   1 
ATOM   2665 C CA  . ARG A 1 385 ? 186.083 141.302 113.652 1.00 141.48 ? 385 ARG A CA  1 
ATOM   2666 C C   . ARG A 1 385 ? 186.863 142.610 113.715 1.00 141.48 ? 385 ARG A C   1 
ATOM   2667 O O   . ARG A 1 385 ? 187.046 143.184 114.788 1.00 141.48 ? 385 ARG A O   1 
ATOM   2668 C CB  . ARG A 1 385 ? 184.584 141.583 113.720 1.00 141.48 ? 385 ARG A CB  1 
ATOM   2669 C CG  . ARG A 1 385 ? 183.724 140.453 113.197 1.00 141.48 ? 385 ARG A CG  1 
ATOM   2670 C CD  . ARG A 1 385 ? 182.250 140.724 113.451 1.00 141.48 ? 385 ARG A CD  1 
ATOM   2671 N NE  . ARG A 1 385 ? 181.375 139.749 112.801 1.00 141.48 ? 385 ARG A NE  1 
ATOM   2672 C CZ  . ARG A 1 385 ? 181.295 139.549 111.488 1.00 141.48 ? 385 ARG A CZ  1 
ATOM   2673 N NH1 . ARG A 1 385 ? 182.022 140.270 110.645 1.00 141.48 ? 385 ARG A NH1 1 
ATOM   2674 N NH2 . ARG A 1 385 ? 180.466 138.632 111.014 1.00 141.48 ? 385 ARG A NH2 1 
ATOM   2675 N N   . PRO B 2 18  ? 147.663 152.272 119.458 1.00 117.41 ? 18  PRO B N   1 
ATOM   2676 C CA  . PRO B 2 18  ? 147.203 152.887 120.711 1.00 117.41 ? 18  PRO B CA  1 
ATOM   2677 C C   . PRO B 2 18  ? 146.091 152.102 121.390 1.00 117.41 ? 18  PRO B C   1 
ATOM   2678 O O   . PRO B 2 18  ? 144.964 152.092 120.897 1.00 117.41 ? 18  PRO B O   1 
ATOM   2679 C CB  . PRO B 2 18  ? 146.694 154.260 120.260 1.00 117.41 ? 18  PRO B CB  1 
ATOM   2680 C CG  . PRO B 2 18  ? 146.316 154.073 118.831 1.00 117.41 ? 18  PRO B CG  1 
ATOM   2681 C CD  . PRO B 2 18  ? 147.282 153.066 118.276 1.00 117.41 ? 18  PRO B CD  1 
ATOM   2682 N N   . LYS B 2 19  ? 146.404 151.458 122.516 1.00 110.21 ? 19  LYS B N   1 
ATOM   2683 C CA  . LYS B 2 19  ? 145.421 150.647 123.239 1.00 110.21 ? 19  LYS B CA  1 
ATOM   2684 C C   . LYS B 2 19  ? 145.418 151.069 124.708 1.00 110.21 ? 19  LYS B C   1 
ATOM   2685 O O   . LYS B 2 19  ? 146.436 151.013 125.403 1.00 110.21 ? 19  LYS B O   1 
ATOM   2686 C CB  . LYS B 2 19  ? 145.679 149.154 123.057 1.00 110.21 ? 19  LYS B CB  1 
ATOM   2687 C CG  . LYS B 2 19  ? 146.966 148.640 123.641 1.00 110.21 ? 19  LYS B CG  1 
ATOM   2688 C CD  . LYS B 2 19  ? 147.080 147.144 123.429 1.00 110.21 ? 19  LYS B CD  1 
ATOM   2689 C CE  . LYS B 2 19  ? 147.352 146.832 121.974 1.00 110.21 ? 19  LYS B CE  1 
ATOM   2690 N NZ  . LYS B 2 19  ? 148.680 147.337 121.563 1.00 110.21 ? 19  LYS B NZ  1 
ATOM   2691 N N   . ILE B 2 20  ? 144.251 151.513 125.161 1.00 105.79 ? 20  ILE B N   1 
ATOM   2692 C CA  . ILE B 2 20  ? 144.059 151.995 126.520 1.00 105.79 ? 20  ILE B CA  1 
ATOM   2693 C C   . ILE B 2 20  ? 143.421 150.936 127.406 1.00 105.79 ? 20  ILE B C   1 
ATOM   2694 O O   . ILE B 2 20  ? 143.785 150.786 128.576 1.00 105.79 ? 20  ILE B O   1 
ATOM   2695 C CB  . ILE B 2 20  ? 143.225 153.295 126.491 1.00 105.79 ? 20  ILE B CB  1 
ATOM   2696 C CG1 . ILE B 2 20  ? 144.100 154.490 126.125 1.00 105.79 ? 20  ILE B CG1 1 
ATOM   2697 C CG2 . ILE B 2 20  ? 142.453 153.482 127.752 1.00 105.79 ? 20  ILE B CG2 1 
ATOM   2698 C CD1 . ILE B 2 20  ? 143.331 155.792 126.061 1.00 105.79 ? 20  ILE B CD1 1 
ATOM   2699 N N   . PHE B 2 21  ? 142.445 150.197 126.884 1.00 108.34 ? 21  PHE B N   1 
ATOM   2700 C CA  . PHE B 2 21  ? 141.774 149.217 127.724 1.00 108.34 ? 21  PHE B CA  1 
ATOM   2701 C C   . PHE B 2 21  ? 142.735 148.152 128.216 1.00 108.34 ? 21  PHE B C   1 
ATOM   2702 O O   . PHE B 2 21  ? 142.568 147.636 129.323 1.00 108.34 ? 21  PHE B O   1 
ATOM   2703 C CB  . PHE B 2 21  ? 140.612 148.575 126.981 1.00 108.34 ? 21  PHE B CB  1 
ATOM   2704 C CG  . PHE B 2 21  ? 139.709 147.781 127.869 1.00 108.34 ? 21  PHE B CG  1 
ATOM   2705 C CD1 . PHE B 2 21  ? 138.698 148.398 128.583 1.00 108.34 ? 21  PHE B CD1 1 
ATOM   2706 C CD2 . PHE B 2 21  ? 139.877 146.412 127.995 1.00 108.34 ? 21  PHE B CD2 1 
ATOM   2707 C CE1 . PHE B 2 21  ? 137.870 147.665 129.406 1.00 108.34 ? 21  PHE B CE1 1 
ATOM   2708 C CE2 . PHE B 2 21  ? 139.050 145.675 128.815 1.00 108.34 ? 21  PHE B CE2 1 
ATOM   2709 C CZ  . PHE B 2 21  ? 138.046 146.302 129.521 1.00 108.34 ? 21  PHE B CZ  1 
ATOM   2710 N N   . ASN B 2 22  ? 143.750 147.818 127.423 1.00 105.19 ? 22  ASN B N   1 
ATOM   2711 C CA  . ASN B 2 22  ? 144.781 146.907 127.904 1.00 105.19 ? 22  ASN B CA  1 
ATOM   2712 C C   . ASN B 2 22  ? 145.523 147.521 129.087 1.00 105.19 ? 22  ASN B C   1 
ATOM   2713 O O   . ASN B 2 22  ? 145.851 146.830 130.064 1.00 105.19 ? 22  ASN B O   1 
ATOM   2714 C CB  . ASN B 2 22  ? 145.740 146.580 126.762 1.00 105.19 ? 22  ASN B CB  1 
ATOM   2715 C CG  . ASN B 2 22  ? 146.713 145.478 127.104 1.00 105.19 ? 22  ASN B CG  1 
ATOM   2716 O OD1 . ASN B 2 22  ? 146.707 144.949 128.213 1.00 105.19 ? 22  ASN B OD1 1 
ATOM   2717 N ND2 . ASN B 2 22  ? 147.561 145.123 126.148 1.00 105.19 ? 22  ASN B ND2 1 
ATOM   2718 N N   . LEU B 2 23  ? 145.787 148.826 129.012 1.00 103.99 ? 23  LEU B N   1 
ATOM   2719 C CA  . LEU B 2 23  ? 146.439 149.529 130.110 1.00 103.99 ? 23  LEU B CA  1 
ATOM   2720 C C   . LEU B 2 23  ? 145.605 149.474 131.381 1.00 103.99 ? 23  LEU B C   1 
ATOM   2721 O O   . LEU B 2 23  ? 146.136 149.205 132.462 1.00 103.99 ? 23  LEU B O   1 
ATOM   2722 C CB  . LEU B 2 23  ? 146.703 150.980 129.717 1.00 103.99 ? 23  LEU B CB  1 
ATOM   2723 C CG  . LEU B 2 23  ? 147.259 151.867 130.822 1.00 103.99 ? 23  LEU B CG  1 
ATOM   2724 C CD1 . LEU B 2 23  ? 148.736 151.614 130.972 1.00 103.99 ? 23  LEU B CD1 1 
ATOM   2725 C CD2 . LEU B 2 23  ? 146.966 153.332 130.546 1.00 103.99 ? 23  LEU B CD2 1 
ATOM   2726 N N   . PHE B 2 24  ? 144.300 149.732 131.281 1.00 104.35 ? 24  PHE B N   1 
ATOM   2727 C CA  . PHE B 2 24  ? 143.473 149.593 132.476 1.00 104.35 ? 24  PHE B CA  1 
ATOM   2728 C C   . PHE B 2 24  ? 143.326 148.156 132.949 1.00 104.35 ? 24  PHE B C   1 
ATOM   2729 O O   . PHE B 2 24  ? 143.193 147.945 134.151 1.00 104.35 ? 24  PHE B O   1 
ATOM   2730 C CB  . PHE B 2 24  ? 142.092 150.221 132.303 1.00 104.35 ? 24  PHE B CB  1 
ATOM   2731 C CG  . PHE B 2 24  ? 142.114 151.714 132.198 1.00 104.35 ? 24  PHE B CG  1 
ATOM   2732 C CD1 . PHE B 2 24  ? 142.210 152.479 133.346 1.00 104.35 ? 24  PHE B CD1 1 
ATOM   2733 C CD2 . PHE B 2 24  ? 142.027 152.361 130.987 1.00 104.35 ? 24  PHE B CD2 1 
ATOM   2734 C CE1 . PHE B 2 24  ? 142.221 153.847 133.286 1.00 104.35 ? 24  PHE B CE1 1 
ATOM   2735 C CE2 . PHE B 2 24  ? 142.039 153.740 130.937 1.00 104.35 ? 24  PHE B CE2 1 
ATOM   2736 C CZ  . PHE B 2 24  ? 142.137 154.479 132.082 1.00 104.35 ? 24  PHE B CZ  1 
ATOM   2737 N N   . ARG B 2 25  ? 143.446 147.195 132.039 1.00 103.80 ? 25  ARG B N   1 
ATOM   2738 C CA  . ARG B 2 25  ? 143.362 145.787 132.405 1.00 103.80 ? 25  ARG B CA  1 
ATOM   2739 C C   . ARG B 2 25  ? 144.559 145.387 133.271 1.00 103.80 ? 25  ARG B C   1 
ATOM   2740 O O   . ARG B 2 25  ? 144.403 144.688 134.272 1.00 103.80 ? 25  ARG B O   1 
ATOM   2741 C CB  . ARG B 2 25  ? 143.298 144.910 131.154 1.00 103.80 ? 25  ARG B CB  1 
ATOM   2742 C CG  . ARG B 2 25  ? 142.419 143.678 131.305 1.00 103.80 ? 25  ARG B CG  1 
ATOM   2743 C CD  . ARG B 2 25  ? 142.858 142.568 130.364 1.00 103.80 ? 25  ARG B CD  1 
ATOM   2744 N NE  . ARG B 2 25  ? 143.172 143.073 129.031 1.00 103.80 ? 25  ARG B NE  1 
ATOM   2745 C CZ  . ARG B 2 25  ? 144.386 143.052 128.492 1.00 103.80 ? 25  ARG B CZ  1 
ATOM   2746 N NH1 . ARG B 2 25  ? 144.580 143.535 127.272 1.00 103.80 ? 25  ARG B NH1 1 
ATOM   2747 N NH2 . ARG B 2 25  ? 145.408 142.550 129.171 1.00 103.80 ? 25  ARG B NH2 1 
ATOM   2748 N N   . VAL B 2 26  ? 145.753 145.833 132.883 1.00 99.04  ? 26  VAL B N   1 
ATOM   2749 C CA  . VAL B 2 26  ? 146.970 145.525 133.630 1.00 99.04  ? 26  VAL B CA  1 
ATOM   2750 C C   . VAL B 2 26  ? 147.068 146.381 134.892 1.00 99.04  ? 26  VAL B C   1 
ATOM   2751 O O   . VAL B 2 26  ? 147.487 145.890 135.947 1.00 99.04  ? 26  VAL B O   1 
ATOM   2752 C CB  . VAL B 2 26  ? 148.219 145.661 132.734 1.00 99.04  ? 26  VAL B CB  1 
ATOM   2753 C CG1 . VAL B 2 26  ? 148.427 147.091 132.274 1.00 99.04  ? 26  VAL B CG1 1 
ATOM   2754 C CG2 . VAL B 2 26  ? 149.448 145.152 133.459 1.00 99.04  ? 26  VAL B CG2 1 
ATOM   2755 N N   . CYS B 2 27  ? 146.664 147.652 134.828 1.00 96.38  ? 27  CYS B N   1 
ATOM   2756 C CA  . CYS B 2 27  ? 146.662 148.503 136.010 1.00 96.38  ? 27  CYS B CA  1 
ATOM   2757 C C   . CYS B 2 27  ? 145.657 148.057 137.061 1.00 96.38  ? 27  CYS B C   1 
ATOM   2758 O O   . CYS B 2 27  ? 145.973 148.093 138.251 1.00 96.38  ? 27  CYS B O   1 
ATOM   2759 C CB  . CYS B 2 27  ? 146.372 149.951 135.622 1.00 96.38  ? 27  CYS B CB  1 
ATOM   2760 S SG  . CYS B 2 27  ? 146.193 151.064 137.023 1.00 96.38  ? 27  CYS B SG  1 
ATOM   2761 N N   . PHE B 2 28  ? 144.459 147.641 136.654 1.00 96.59  ? 28  PHE B N   1 
ATOM   2762 C CA  . PHE B 2 28  ? 143.475 147.131 137.596 1.00 96.59  ? 28  PHE B CA  1 
ATOM   2763 C C   . PHE B 2 28  ? 143.958 145.849 138.247 1.00 96.59  ? 28  PHE B C   1 
ATOM   2764 O O   . PHE B 2 28  ? 143.781 145.659 139.453 1.00 96.59  ? 28  PHE B O   1 
ATOM   2765 C CB  . PHE B 2 28  ? 142.150 146.897 136.878 1.00 96.59  ? 28  PHE B CB  1 
ATOM   2766 C CG  . PHE B 2 28  ? 141.018 146.555 137.791 1.00 96.59  ? 28  PHE B CG  1 
ATOM   2767 C CD1 . PHE B 2 28  ? 140.554 147.475 138.713 1.00 96.59  ? 28  PHE B CD1 1 
ATOM   2768 C CD2 . PHE B 2 28  ? 140.418 145.311 137.729 1.00 96.59  ? 28  PHE B CD2 1 
ATOM   2769 C CE1 . PHE B 2 28  ? 139.505 147.162 139.553 1.00 96.59  ? 28  PHE B CE1 1 
ATOM   2770 C CE2 . PHE B 2 28  ? 139.373 144.992 138.567 1.00 96.59  ? 28  PHE B CE2 1 
ATOM   2771 C CZ  . PHE B 2 28  ? 138.916 145.917 139.481 1.00 96.59  ? 28  PHE B CZ  1 
ATOM   2772 N N   . ILE B 2 29  ? 144.574 144.956 137.472 1.00 91.63  ? 29  ILE B N   1 
ATOM   2773 C CA  . ILE B 2 29  ? 145.103 143.731 138.057 1.00 91.63  ? 29  ILE B CA  1 
ATOM   2774 C C   . ILE B 2 29  ? 146.206 144.043 139.059 1.00 91.63  ? 29  ILE B C   1 
ATOM   2775 O O   . ILE B 2 29  ? 146.228 143.496 140.168 1.00 91.63  ? 29  ILE B O   1 
ATOM   2776 C CB  . ILE B 2 29  ? 145.593 142.788 136.947 1.00 91.63  ? 29  ILE B CB  1 
ATOM   2777 C CG1 . ILE B 2 29  ? 144.399 142.202 136.199 1.00 91.63  ? 29  ILE B CG1 1 
ATOM   2778 C CG2 . ILE B 2 29  ? 146.458 141.690 137.529 1.00 91.63  ? 29  ILE B CG2 1 
ATOM   2779 C CD1 . ILE B 2 29  ? 143.679 141.116 136.955 1.00 91.63  ? 29  ILE B CD1 1 
ATOM   2780 N N   . SER B 2 30  ? 147.128 144.937 138.697 1.00 85.78  ? 30  SER B N   1 
ATOM   2781 C CA  . SER B 2 30  ? 148.216 145.284 139.605 1.00 85.78  ? 30  SER B CA  1 
ATOM   2782 C C   . SER B 2 30  ? 147.686 145.934 140.873 1.00 85.78  ? 30  SER B C   1 
ATOM   2783 O O   . SER B 2 30  ? 148.121 145.610 141.982 1.00 85.78  ? 30  SER B O   1 
ATOM   2784 C CB  . SER B 2 30  ? 149.197 146.221 138.907 1.00 85.78  ? 30  SER B CB  1 
ATOM   2785 O OG  . SER B 2 30  ? 148.668 147.533 138.848 1.00 85.78  ? 30  SER B OG  1 
ATOM   2786 N N   . LEU B 2 31  ? 146.745 146.865 140.724 1.00 81.74  ? 31  LEU B N   1 
ATOM   2787 C CA  . LEU B 2 31  ? 146.202 147.567 141.877 1.00 81.74  ? 31  LEU B CA  1 
ATOM   2788 C C   . LEU B 2 31  ? 145.426 146.621 142.780 1.00 81.74  ? 31  LEU B C   1 
ATOM   2789 O O   . LEU B 2 31  ? 145.513 146.714 144.010 1.00 81.74  ? 31  LEU B O   1 
ATOM   2790 C CB  . LEU B 2 31  ? 145.315 148.707 141.391 1.00 81.74  ? 31  LEU B CB  1 
ATOM   2791 C CG  . LEU B 2 31  ? 144.705 149.615 142.440 1.00 81.74  ? 31  LEU B CG  1 
ATOM   2792 C CD1 . LEU B 2 31  ? 145.825 150.309 143.168 1.00 81.74  ? 31  LEU B CD1 1 
ATOM   2793 C CD2 . LEU B 2 31  ? 143.787 150.622 141.786 1.00 81.74  ? 31  LEU B CD2 1 
ATOM   2794 N N   . LEU B 2 32  ? 144.672 145.697 142.192 1.00 80.32  ? 32  LEU B N   1 
ATOM   2795 C CA  . LEU B 2 32  ? 143.959 144.714 142.988 1.00 80.32  ? 32  LEU B CA  1 
ATOM   2796 C C   . LEU B 2 32  ? 144.926 143.801 143.723 1.00 80.32  ? 32  LEU B C   1 
ATOM   2797 O O   . LEU B 2 32  ? 144.659 143.400 144.854 1.00 80.32  ? 32  LEU B O   1 
ATOM   2798 C CB  . LEU B 2 32  ? 143.019 143.906 142.098 1.00 80.32  ? 32  LEU B CB  1 
ATOM   2799 C CG  . LEU B 2 32  ? 142.046 142.966 142.802 1.00 80.32  ? 32  LEU B CG  1 
ATOM   2800 C CD1 . LEU B 2 32  ? 140.723 142.973 142.069 1.00 80.32  ? 32  LEU B CD1 1 
ATOM   2801 C CD2 . LEU B 2 32  ? 142.604 141.557 142.865 1.00 80.32  ? 32  LEU B CD2 1 
ATOM   2802 N N   . LEU B 2 33  ? 146.048 143.448 143.098 1.00 76.69  ? 33  LEU B N   1 
ATOM   2803 C CA  . LEU B 2 33  ? 147.032 142.626 143.796 1.00 76.69  ? 33  LEU B CA  1 
ATOM   2804 C C   . LEU B 2 33  ? 147.675 143.395 144.946 1.00 76.69  ? 33  LEU B C   1 
ATOM   2805 O O   . LEU B 2 33  ? 147.938 142.830 146.017 1.00 76.69  ? 33  LEU B O   1 
ATOM   2806 C CB  . LEU B 2 33  ? 148.083 142.132 142.809 1.00 76.69  ? 33  LEU B CB  1 
ATOM   2807 C CG  . LEU B 2 33  ? 149.263 141.366 143.385 1.00 76.69  ? 33  LEU B CG  1 
ATOM   2808 C CD1 . LEU B 2 33  ? 148.864 139.932 143.629 1.00 76.69  ? 33  LEU B CD1 1 
ATOM   2809 C CD2 . LEU B 2 33  ? 150.425 141.429 142.427 1.00 76.69  ? 33  LEU B CD2 1 
ATOM   2810 N N   . ILE B 2 34  ? 147.931 144.688 144.740 1.00 75.66  ? 34  ILE B N   1 
ATOM   2811 C CA  . ILE B 2 34  ? 148.439 145.534 145.817 1.00 75.66  ? 34  ILE B CA  1 
ATOM   2812 C C   . ILE B 2 34  ? 147.468 145.542 146.986 1.00 75.66  ? 34  ILE B C   1 
ATOM   2813 O O   . ILE B 2 34  ? 147.867 145.398 148.145 1.00 75.66  ? 34  ILE B O   1 
ATOM   2814 C CB  . ILE B 2 34  ? 148.696 146.961 145.308 1.00 75.66  ? 34  ILE B CB  1 
ATOM   2815 C CG1 . ILE B 2 34  ? 149.971 147.024 144.476 1.00 75.66  ? 34  ILE B CG1 1 
ATOM   2816 C CG2 . ILE B 2 34  ? 148.774 147.928 146.464 1.00 75.66  ? 34  ILE B CG2 1 
ATOM   2817 C CD1 . ILE B 2 34  ? 150.243 148.399 143.915 1.00 75.66  ? 34  ILE B CD1 1 
ATOM   2818 N N   . ALA B 2 35  ? 146.183 145.716 146.703 1.00 73.09  ? 35  ALA B N   1 
ATOM   2819 C CA  . ALA B 2 35  ? 145.163 145.704 147.741 1.00 73.09  ? 35  ALA B CA  1 
ATOM   2820 C C   . ALA B 2 35  ? 144.960 144.329 148.354 1.00 73.09  ? 35  ALA B C   1 
ATOM   2821 O O   . ALA B 2 35  ? 144.527 144.236 149.503 1.00 73.09  ? 35  ALA B O   1 
ATOM   2822 C CB  . ALA B 2 35  ? 143.834 146.212 147.184 1.00 73.09  ? 35  ALA B CB  1 
ATOM   2823 N N   . ALA B 2 36  ? 145.255 143.263 147.620 1.00 72.55  ? 36  ALA B N   1 
ATOM   2824 C CA  . ALA B 2 36  ? 145.126 141.923 148.166 1.00 72.55  ? 36  ALA B CA  1 
ATOM   2825 C C   . ALA B 2 36  ? 146.225 141.632 149.172 1.00 72.55  ? 36  ALA B C   1 
ATOM   2826 O O   . ALA B 2 36  ? 145.961 141.082 150.241 1.00 72.55  ? 36  ALA B O   1 
ATOM   2827 C CB  . ALA B 2 36  ? 145.153 140.889 147.042 1.00 72.55  ? 36  ALA B CB  1 
ATOM   2828 N N   . VAL B 2 37  ? 147.466 142.001 148.850 1.00 70.90  ? 37  VAL B N   1 
ATOM   2829 C CA  . VAL B 2 37  ? 148.554 141.789 149.800 1.00 70.90  ? 37  VAL B CA  1 
ATOM   2830 C C   . VAL B 2 37  ? 148.424 142.681 151.027 1.00 70.90  ? 37  VAL B C   1 
ATOM   2831 O O   . VAL B 2 37  ? 148.731 142.243 152.142 1.00 70.90  ? 37  VAL B O   1 
ATOM   2832 C CB  . VAL B 2 37  ? 149.909 141.991 149.111 1.00 70.90  ? 37  VAL B CB  1 
ATOM   2833 C CG1 . VAL B 2 37  ? 151.019 141.943 150.119 1.00 70.90  ? 37  VAL B CG1 1 
ATOM   2834 C CG2 . VAL B 2 37  ? 150.113 140.905 148.098 1.00 70.90  ? 37  VAL B CG2 1 
ATOM   2835 N N   . GLU B 2 38  ? 147.916 143.892 150.825 1.00 72.40  ? 38  GLU B N   1 
ATOM   2836 C CA  . GLU B 2 38  ? 147.704 144.824 151.920 1.00 72.40  ? 38  GLU B CA  1 
ATOM   2837 C C   . GLU B 2 38  ? 146.707 144.220 152.905 1.00 72.40  ? 38  GLU B C   1 
ATOM   2838 O O   . GLU B 2 38  ? 146.906 144.289 154.118 1.00 72.40  ? 38  GLU B O   1 
ATOM   2839 C CB  . GLU B 2 38  ? 147.184 146.164 151.396 1.00 72.40  ? 38  GLU B CB  1 
ATOM   2840 C CG  . GLU B 2 38  ? 148.219 147.277 151.406 1.00 72.40  ? 38  GLU B CG  1 
ATOM   2841 C CD  . GLU B 2 38  ? 149.639 146.754 151.299 1.00 72.40  ? 38  GLU B CD  1 
ATOM   2842 O OE1 . GLU B 2 38  ? 150.091 146.063 152.235 1.00 72.40  ? 38  GLU B OE1 1 
ATOM   2843 O OE2 . GLU B 2 38  ? 150.301 147.033 150.277 1.00 72.40  ? 38  GLU B OE2 1 
ATOM   2844 N N   . TYR B 2 39  ? 145.637 143.626 152.381 1.00 72.47  ? 39  TYR B N   1 
ATOM   2845 C CA  . TYR B 2 39  ? 144.635 143.003 153.234 1.00 72.47  ? 39  TYR B CA  1 
ATOM   2846 C C   . TYR B 2 39  ? 145.148 141.699 153.819 1.00 72.47  ? 39  TYR B C   1 
ATOM   2847 O O   . TYR B 2 39  ? 144.744 141.316 154.913 1.00 72.47  ? 39  TYR B O   1 
ATOM   2848 C CB  . TYR B 2 39  ? 143.334 142.758 152.480 1.00 72.47  ? 39  TYR B CB  1 
ATOM   2849 C CG  . TYR B 2 39  ? 142.424 141.842 153.256 1.00 72.47  ? 39  TYR B CG  1 
ATOM   2850 C CD1 . TYR B 2 39  ? 142.297 140.506 152.929 1.00 72.47  ? 39  TYR B CD1 1 
ATOM   2851 C CD2 . TYR B 2 39  ? 141.729 142.312 154.355 1.00 72.47  ? 39  TYR B CD2 1 
ATOM   2852 C CE1 . TYR B 2 39  ? 141.484 139.679 153.656 1.00 72.47  ? 39  TYR B CE1 1 
ATOM   2853 C CE2 . TYR B 2 39  ? 140.913 141.491 155.085 1.00 72.47  ? 39  TYR B CE2 1 
ATOM   2854 C CZ  . TYR B 2 39  ? 140.796 140.175 154.733 1.00 72.47  ? 39  TYR B CZ  1 
ATOM   2855 O OH  . TYR B 2 39  ? 139.979 139.353 155.465 1.00 72.47  ? 39  TYR B OH  1 
ATOM   2856 N N   . PHE B 2 40  ? 146.019 140.989 153.106 1.00 69.40  ? 40  PHE B N   1 
ATOM   2857 C CA  . PHE B 2 40  ? 146.620 139.792 153.686 1.00 69.40  ? 40  PHE B CA  1 
ATOM   2858 C C   . PHE B 2 40  ? 147.412 140.140 154.931 1.00 69.40  ? 40  PHE B C   1 
ATOM   2859 O O   . PHE B 2 40  ? 147.269 139.495 155.974 1.00 69.40  ? 40  PHE B O   1 
ATOM   2860 C CB  . PHE B 2 40  ? 147.524 139.100 152.673 1.00 69.40  ? 40  PHE B CB  1 
ATOM   2861 C CG  . PHE B 2 40  ? 148.555 138.202 153.296 1.00 69.40  ? 40  PHE B CG  1 
ATOM   2862 C CD1 . PHE B 2 40  ? 148.232 136.919 153.675 1.00 69.40  ? 40  PHE B CD1 1 
ATOM   2863 C CD2 . PHE B 2 40  ? 149.848 138.640 153.495 1.00 69.40  ? 40  PHE B CD2 1 
ATOM   2864 C CE1 . PHE B 2 40  ? 149.179 136.096 154.242 1.00 69.40  ? 40  PHE B CE1 1 
ATOM   2865 C CE2 . PHE B 2 40  ? 150.794 137.819 154.063 1.00 69.40  ? 40  PHE B CE2 1 
ATOM   2866 C CZ  . PHE B 2 40  ? 150.459 136.549 154.435 1.00 69.40  ? 40  PHE B CZ  1 
ATOM   2867 N N   . LYS B 2 41  ? 148.260 141.159 154.837 1.00 64.97  ? 41  LYS B N   1 
ATOM   2868 C CA  . LYS B 2 41  ? 149.035 141.572 156.000 1.00 64.97  ? 41  LYS B CA  1 
ATOM   2869 C C   . LYS B 2 41  ? 148.119 141.996 157.137 1.00 64.97  ? 41  LYS B C   1 
ATOM   2870 O O   . LYS B 2 41  ? 148.289 141.556 158.280 1.00 64.97  ? 41  LYS B O   1 
ATOM   2871 C CB  . LYS B 2 41  ? 149.983 142.705 155.621 1.00 64.97  ? 41  LYS B CB  1 
ATOM   2872 C CG  . LYS B 2 41  ? 151.180 142.261 154.813 1.00 64.97  ? 41  LYS B CG  1 
ATOM   2873 C CD  . LYS B 2 41  ? 152.241 143.328 154.780 1.00 64.97  ? 41  LYS B CD  1 
ATOM   2874 C CE  . LYS B 2 41  ? 151.666 144.650 154.368 1.00 64.97  ? 41  LYS B CE  1 
ATOM   2875 N NZ  . LYS B 2 41  ? 152.521 145.759 154.833 1.00 64.97  ? 41  LYS B NZ  1 
ATOM   2876 N N   . TYR B 2 42  ? 147.114 142.817 156.836 1.00 65.20  ? 42  TYR B N   1 
ATOM   2877 C CA  . TYR B 2 42  ? 146.196 143.266 157.876 1.00 65.20  ? 42  TYR B CA  1 
ATOM   2878 C C   . TYR B 2 42  ? 145.405 142.121 158.494 1.00 65.20  ? 42  TYR B C   1 
ATOM   2879 O O   . TYR B 2 42  ? 145.240 142.077 159.716 1.00 65.20  ? 42  TYR B O   1 
ATOM   2880 C CB  . TYR B 2 42  ? 145.244 144.307 157.305 1.00 65.20  ? 42  TYR B CB  1 
ATOM   2881 C CG  . TYR B 2 42  ? 144.228 144.817 158.285 1.00 65.20  ? 42  TYR B CG  1 
ATOM   2882 C CD1 . TYR B 2 42  ? 142.934 144.334 158.286 1.00 65.20  ? 42  TYR B CD1 1 
ATOM   2883 C CD2 . TYR B 2 42  ? 144.564 145.788 159.208 1.00 65.20  ? 42  TYR B CD2 1 
ATOM   2884 C CE1 . TYR B 2 42  ? 142.008 144.803 159.175 1.00 65.20  ? 42  TYR B CE1 1 
ATOM   2885 C CE2 . TYR B 2 42  ? 143.645 146.259 160.101 1.00 65.20  ? 42  TYR B CE2 1 
ATOM   2886 C CZ  . TYR B 2 42  ? 142.368 145.767 160.082 1.00 65.20  ? 42  TYR B CZ  1 
ATOM   2887 O OH  . TYR B 2 42  ? 141.446 146.244 160.980 1.00 65.20  ? 42  TYR B OH  1 
ATOM   2888 N N   . GLY B 2 43  ? 144.906 141.200 157.678 1.00 65.24  ? 43  GLY B N   1 
ATOM   2889 C CA  . GLY B 2 43  ? 144.121 140.099 158.199 1.00 65.24  ? 43  GLY B CA  1 
ATOM   2890 C C   . GLY B 2 43  ? 144.937 139.159 159.054 1.00 65.24  ? 43  GLY B C   1 
ATOM   2891 O O   . GLY B 2 43  ? 144.495 138.734 160.120 1.00 65.24  ? 43  GLY B O   1 
ATOM   2892 N N   . THR B 2 44  ? 146.137 138.808 158.597 1.00 61.89  ? 44  THR B N   1 
ATOM   2893 C CA  . THR B 2 44  ? 146.986 137.974 159.431 1.00 61.89  ? 44  THR B CA  1 
ATOM   2894 C C   . THR B 2 44  ? 147.515 138.709 160.648 1.00 61.89  ? 44  THR B C   1 
ATOM   2895 O O   . THR B 2 44  ? 148.004 138.058 161.570 1.00 61.89  ? 44  THR B O   1 
ATOM   2896 C CB  . THR B 2 44  ? 148.159 137.426 158.633 1.00 61.89  ? 44  THR B CB  1 
ATOM   2897 O OG1 . THR B 2 44  ? 149.035 138.497 158.283 1.00 61.89  ? 44  THR B OG1 1 
ATOM   2898 C CG2 . THR B 2 44  ? 147.673 136.740 157.389 1.00 61.89  ? 44  THR B CG2 1 
ATOM   2899 N N   . ARG B 2 45  ? 147.437 140.034 160.686 1.00 61.68  ? 45  ARG B N   1 
ATOM   2900 C CA  . ARG B 2 45  ? 147.856 140.726 161.894 1.00 61.68  ? 45  ARG B CA  1 
ATOM   2901 C C   . ARG B 2 45  ? 146.745 140.884 162.918 1.00 61.68  ? 45  ARG B C   1 
ATOM   2902 O O   . ARG B 2 45  ? 147.001 140.718 164.112 1.00 61.68  ? 45  ARG B O   1 
ATOM   2903 C CB  . ARG B 2 45  ? 148.424 142.101 161.550 1.00 61.68  ? 45  ARG B CB  1 
ATOM   2904 C CG  . ARG B 2 45  ? 149.154 142.735 162.692 1.00 61.68  ? 45  ARG B CG  1 
ATOM   2905 C CD  . ARG B 2 45  ? 149.250 144.217 162.514 1.00 61.68  ? 45  ARG B CD  1 
ATOM   2906 N NE  . ARG B 2 45  ? 147.974 144.870 162.753 1.00 61.68  ? 45  ARG B NE  1 
ATOM   2907 C CZ  . ARG B 2 45  ? 147.420 145.737 161.918 1.00 61.68  ? 45  ARG B CZ  1 
ATOM   2908 N NH1 . ARG B 2 45  ? 146.254 146.289 162.213 1.00 61.68  ? 45  ARG B NH1 1 
ATOM   2909 N NH2 . ARG B 2 45  ? 148.034 146.054 160.789 1.00 61.68  ? 45  ARG B NH2 1 
ATOM   2910 N N   . ILE B 2 46  ? 145.521 141.209 162.501 1.00 63.22  ? 46  ILE B N   1 
ATOM   2911 C CA  . ILE B 2 46  ? 144.452 141.352 163.485 1.00 63.22  ? 46  ILE B CA  1 
ATOM   2912 C C   . ILE B 2 46  ? 144.032 140.020 164.081 1.00 63.22  ? 46  ILE B C   1 
ATOM   2913 O O   . ILE B 2 46  ? 143.746 139.957 165.280 1.00 63.22  ? 46  ILE B O   1 
ATOM   2914 C CB  . ILE B 2 46  ? 143.221 142.077 162.919 1.00 63.22  ? 46  ILE B CB  1 
ATOM   2915 C CG1 . ILE B 2 46  ? 142.607 141.300 161.762 1.00 63.22  ? 46  ILE B CG1 1 
ATOM   2916 C CG2 . ILE B 2 46  ? 143.557 143.497 162.542 1.00 63.22  ? 46  ILE B CG2 1 
ATOM   2917 C CD1 . ILE B 2 46  ? 141.280 141.839 161.325 1.00 63.22  ? 46  ILE B CD1 1 
ATOM   2918 N N   . ASN B 2 47  ? 143.973 138.952 163.297 1.00 62.34  ? 47  ASN B N   1 
ATOM   2919 C CA  . ASN B 2 47  ? 143.676 137.628 163.824 1.00 62.34  ? 47  ASN B CA  1 
ATOM   2920 C C   . ASN B 2 47  ? 144.835 136.696 163.482 1.00 62.34  ? 47  ASN B C   1 
ATOM   2921 O O   . ASN B 2 47  ? 144.787 135.895 162.554 1.00 62.34  ? 47  ASN B O   1 
ATOM   2922 C CB  . ASN B 2 47  ? 142.336 137.117 163.303 1.00 62.34  ? 47  ASN B CB  1 
ATOM   2923 C CG  . ASN B 2 47  ? 142.201 137.250 161.808 1.00 62.34  ? 47  ASN B CG  1 
ATOM   2924 O OD1 . ASN B 2 47  ? 141.480 138.105 161.309 1.00 62.34  ? 47  ASN B OD1 1 
ATOM   2925 N ND2 . ASN B 2 47  ? 142.903 136.394 161.080 1.00 62.34  ? 47  ASN B ND2 1 
ATOM   2926 N N   . TYR B 2 48  ? 145.874 136.781 164.299 1.00 57.86  ? 48  TYR B N   1 
ATOM   2927 C CA  . TYR B 2 48  ? 147.090 136.011 164.126 1.00 57.86  ? 48  TYR B CA  1 
ATOM   2928 C C   . TYR B 2 48  ? 147.060 134.705 164.883 1.00 57.86  ? 48  TYR B C   1 
ATOM   2929 O O   . TYR B 2 48  ? 147.712 133.749 164.461 1.00 57.86  ? 48  TYR B O   1 
ATOM   2930 C CB  . TYR B 2 48  ? 148.288 136.827 164.588 1.00 57.86  ? 48  TYR B CB  1 
ATOM   2931 C CG  . TYR B 2 48  ? 148.326 137.075 166.072 1.00 57.86  ? 48  TYR B CG  1 
ATOM   2932 C CD1 . TYR B 2 48  ? 149.051 136.257 166.912 1.00 57.86  ? 48  TYR B CD1 1 
ATOM   2933 C CD2 . TYR B 2 48  ? 147.634 138.129 166.633 1.00 57.86  ? 48  TYR B CD2 1 
ATOM   2934 C CE1 . TYR B 2 48  ? 149.090 136.480 168.258 1.00 57.86  ? 48  TYR B CE1 1 
ATOM   2935 C CE2 . TYR B 2 48  ? 147.667 138.358 167.980 1.00 57.86  ? 48  TYR B CE2 1 
ATOM   2936 C CZ  . TYR B 2 48  ? 148.397 137.530 168.785 1.00 57.86  ? 48  TYR B CZ  1 
ATOM   2937 O OH  . TYR B 2 48  ? 148.435 137.753 170.134 1.00 57.86  ? 48  TYR B OH  1 
ATOM   2938 N N   . GLU B 2 49  ? 146.311 134.635 165.976 1.00 61.96  ? 49  GLU B N   1 
ATOM   2939 C CA  . GLU B 2 49  ? 146.290 133.447 166.808 1.00 61.96  ? 49  GLU B CA  1 
ATOM   2940 C C   . GLU B 2 49  ? 145.773 132.230 166.069 1.00 61.96  ? 49  GLU B C   1 
ATOM   2941 O O   . GLU B 2 49  ? 145.984 131.110 166.536 1.00 61.96  ? 49  GLU B O   1 
ATOM   2942 C CB  . GLU B 2 49  ? 145.437 133.695 168.045 1.00 61.96  ? 49  GLU B CB  1 
ATOM   2943 C CG  . GLU B 2 49  ? 143.965 133.550 167.787 1.00 61.96  ? 49  GLU B CG  1 
ATOM   2944 C CD  . GLU B 2 49  ? 143.372 134.772 167.138 1.00 61.96  ? 49  GLU B CD  1 
ATOM   2945 O OE1 . GLU B 2 49  ? 142.135 134.833 166.996 1.00 61.96  ? 49  GLU B OE1 1 
ATOM   2946 O OE2 . GLU B 2 49  ? 144.143 135.676 166.769 1.00 61.96  ? 49  GLU B OE2 1 
ATOM   2947 N N   . TRP B 2 50  ? 145.097 132.416 164.941 1.00 65.10  ? 50  TRP B N   1 
ATOM   2948 C CA  . TRP B 2 50  ? 144.714 131.272 164.131 1.00 65.10  ? 50  TRP B CA  1 
ATOM   2949 C C   . TRP B 2 50  ? 145.942 130.534 163.623 1.00 65.10  ? 50  TRP B C   1 
ATOM   2950 O O   . TRP B 2 50  ? 145.977 129.300 163.621 1.00 65.10  ? 50  TRP B O   1 
ATOM   2951 C CB  . TRP B 2 50  ? 143.846 131.722 162.961 1.00 65.10  ? 50  TRP B CB  1 
ATOM   2952 C CG  . TRP B 2 50  ? 143.215 130.585 162.257 1.00 65.10  ? 50  TRP B CG  1 
ATOM   2953 C CD1 . TRP B 2 50  ? 142.060 129.963 162.593 1.00 65.10  ? 50  TRP B CD1 1 
ATOM   2954 C CD2 . TRP B 2 50  ? 143.720 129.904 161.109 1.00 65.10  ? 50  TRP B CD2 1 
ATOM   2955 N NE1 . TRP B 2 50  ? 141.802 128.944 161.720 1.00 65.10  ? 50  TRP B NE1 1 
ATOM   2956 C CE2 . TRP B 2 50  ? 142.810 128.886 160.798 1.00 65.10  ? 50  TRP B CE2 1 
ATOM   2957 C CE3 . TRP B 2 50  ? 144.852 130.058 160.313 1.00 65.10  ? 50  TRP B CE3 1 
ATOM   2958 C CZ2 . TRP B 2 50  ? 142.994 128.028 159.725 1.00 65.10  ? 50  TRP B CZ2 1 
ATOM   2959 C CZ3 . TRP B 2 50  ? 145.032 129.205 159.249 1.00 65.10  ? 50  TRP B CZ3 1 
ATOM   2960 C CH2 . TRP B 2 50  ? 144.110 128.204 158.964 1.00 65.10  ? 50  TRP B CH2 1 
ATOM   2961 N N   . PHE B 2 51  ? 146.960 131.276 163.189 1.00 60.28  ? 51  PHE B N   1 
ATOM   2962 C CA  . PHE B 2 51  ? 148.156 130.650 162.640 1.00 60.28  ? 51  PHE B CA  1 
ATOM   2963 C C   . PHE B 2 51  ? 149.056 130.090 163.726 1.00 60.28  ? 51  PHE B C   1 
ATOM   2964 O O   . PHE B 2 51  ? 149.631 129.015 163.553 1.00 60.28  ? 51  PHE B O   1 
ATOM   2965 C CB  . PHE B 2 51  ? 148.925 131.651 161.790 1.00 60.28  ? 51  PHE B CB  1 
ATOM   2966 C CG  . PHE B 2 51  ? 148.091 132.317 160.746 1.00 60.28  ? 51  PHE B CG  1 
ATOM   2967 C CD1 . PHE B 2 51  ? 147.986 131.776 159.487 1.00 60.28  ? 51  PHE B CD1 1 
ATOM   2968 C CD2 . PHE B 2 51  ? 147.413 133.479 161.023 1.00 60.28  ? 51  PHE B CD2 1 
ATOM   2969 C CE1 . PHE B 2 51  ? 147.223 132.380 158.530 1.00 60.28  ? 51  PHE B CE1 1 
ATOM   2970 C CE2 . PHE B 2 51  ? 146.649 134.083 160.066 1.00 60.28  ? 51  PHE B CE2 1 
ATOM   2971 C CZ  . PHE B 2 51  ? 146.554 133.533 158.820 1.00 60.28  ? 51  PHE B CZ  1 
ATOM   2972 N N   . HIS B 2 52  ? 149.185 130.785 164.846 1.00 60.93  ? 52  HIS B N   1 
ATOM   2973 C CA  . HIS B 2 52  ? 150.161 130.391 165.846 1.00 60.93  ? 52  HIS B CA  1 
ATOM   2974 C C   . HIS B 2 52  ? 149.591 129.455 166.899 1.00 60.93  ? 52  HIS B C   1 
ATOM   2975 O O   . HIS B 2 52  ? 150.240 128.469 167.259 1.00 60.93  ? 52  HIS B O   1 
ATOM   2976 C CB  . HIS B 2 52  ? 150.733 131.633 166.520 1.00 60.93  ? 52  HIS B CB  1 
ATOM   2977 C CG  . HIS B 2 52  ? 151.407 132.567 165.571 1.00 60.93  ? 52  HIS B CG  1 
ATOM   2978 N ND1 . HIS B 2 52  ? 152.302 132.137 164.619 1.00 60.93  ? 52  HIS B ND1 1 
ATOM   2979 C CD2 . HIS B 2 52  ? 151.311 133.905 165.420 1.00 60.93  ? 52  HIS B CD2 1 
ATOM   2980 C CE1 . HIS B 2 52  ? 152.731 133.172 163.924 1.00 60.93  ? 52  HIS B CE1 1 
ATOM   2981 N NE2 . HIS B 2 52  ? 152.144 134.257 164.389 1.00 60.93  ? 52  HIS B NE2 1 
ATOM   2982 N N   . CYS B 2 53  ? 148.395 129.738 167.404 1.00 66.02  ? 53  CYS B N   1 
ATOM   2983 C CA  . CYS B 2 53  ? 147.822 129.009 168.526 1.00 66.02  ? 53  CYS B CA  1 
ATOM   2984 C C   . CYS B 2 53  ? 146.852 127.947 168.033 1.00 66.02  ? 53  CYS B C   1 
ATOM   2985 O O   . CYS B 2 53  ? 146.064 128.196 167.118 1.00 66.02  ? 53  CYS B O   1 
ATOM   2986 C CB  . CYS B 2 53  ? 147.108 129.961 169.480 1.00 66.02  ? 53  CYS B CB  1 
ATOM   2987 S SG  . CYS B 2 53  ? 148.107 131.351 169.994 1.00 66.02  ? 53  CYS B SG  1 
ATOM   2988 N N   . THR B 2 54  ? 146.916 126.768 168.638 1.00 66.59  ? 54  THR B N   1 
ATOM   2989 C CA  . THR B 2 54  ? 145.974 125.698 168.342 1.00 66.59  ? 54  THR B CA  1 
ATOM   2990 C C   . THR B 2 54  ? 145.228 125.340 169.614 1.00 66.59  ? 54  THR B C   1 
ATOM   2991 O O   . THR B 2 54  ? 145.865 124.981 170.613 1.00 66.59  ? 54  THR B O   1 
ATOM   2992 C CB  . THR B 2 54  ? 146.696 124.472 167.794 1.00 66.59  ? 54  THR B CB  1 
ATOM   2993 O OG1 . THR B 2 54  ? 147.609 123.983 168.780 1.00 66.59  ? 54  THR B OG1 1 
ATOM   2994 C CG2 . THR B 2 54  ? 147.471 124.834 166.549 1.00 66.59  ? 54  THR B CG2 1 
ATOM   2995 N N   . PRO B 2 55  ? 143.899 125.423 169.638 1.00 64.30  ? 55  PRO B N   1 
ATOM   2996 C CA  . PRO B 2 55  ? 143.157 125.143 170.873 1.00 64.30  ? 55  PRO B CA  1 
ATOM   2997 C C   . PRO B 2 55  ? 143.227 123.666 171.224 1.00 64.30  ? 55  PRO B C   1 
ATOM   2998 O O   . PRO B 2 55  ? 143.069 122.804 170.361 1.00 64.30  ? 55  PRO B O   1 
ATOM   2999 C CB  . PRO B 2 55  ? 141.732 125.577 170.529 1.00 64.30  ? 55  PRO B CB  1 
ATOM   3000 C CG  . PRO B 2 55  ? 141.657 125.403 169.072 1.00 64.30  ? 55  PRO B CG  1 
ATOM   3001 C CD  . PRO B 2 55  ? 142.996 125.786 168.538 1.00 64.30  ? 55  PRO B CD  1 
ATOM   3002 N N   . ILE B 2 56  ? 143.470 123.382 172.495 1.00 66.67  ? 56  ILE B N   1 
ATOM   3003 C CA  . ILE B 2 56  ? 143.521 122.021 173.007 1.00 66.67  ? 56  ILE B CA  1 
ATOM   3004 C C   . ILE B 2 56  ? 142.395 121.863 174.011 1.00 66.67  ? 56  ILE B C   1 
ATOM   3005 O O   . ILE B 2 56  ? 142.472 122.394 175.122 1.00 66.67  ? 56  ILE B O   1 
ATOM   3006 C CB  . ILE B 2 56  ? 144.875 121.720 173.658 1.00 66.67  ? 56  ILE B CB  1 
ATOM   3007 C CG1 . ILE B 2 56  ? 145.992 121.846 172.633 1.00 66.67  ? 56  ILE B CG1 1 
ATOM   3008 C CG2 . ILE B 2 56  ? 144.873 120.341 174.256 1.00 66.67  ? 56  ILE B CG2 1 
ATOM   3009 C CD1 . ILE B 2 56  ? 145.855 120.897 171.484 1.00 66.67  ? 56  ILE B CD1 1 
ATOM   3010 N N   . LYS B 2 57  ? 141.356 121.124 173.641 1.00 70.02  ? 57  LYS B N   1 
ATOM   3011 C CA  . LYS B 2 57  ? 140.195 120.941 174.498 1.00 70.02  ? 57  LYS B CA  1 
ATOM   3012 C C   . LYS B 2 57  ? 140.199 119.530 175.061 1.00 70.02  ? 57  LYS B C   1 
ATOM   3013 O O   . LYS B 2 57  ? 140.317 118.556 174.314 1.00 70.02  ? 57  LYS B O   1 
ATOM   3014 C CB  . LYS B 2 57  ? 138.896 121.227 173.740 1.00 70.02  ? 57  LYS B CB  1 
ATOM   3015 C CG  . LYS B 2 57  ? 138.679 120.387 172.506 1.00 70.02  ? 57  LYS B CG  1 
ATOM   3016 C CD  . LYS B 2 57  ? 137.330 120.673 171.888 1.00 70.02  ? 57  LYS B CD  1 
ATOM   3017 C CE  . LYS B 2 57  ? 137.313 122.028 171.219 1.00 70.02  ? 57  LYS B CE  1 
ATOM   3018 N NZ  . LYS B 2 57  ? 136.026 122.269 170.516 1.00 70.02  ? 57  LYS B NZ  1 
ATOM   3019 N N   . GLU B 2 58  ? 140.091 119.428 176.378 1.00 77.65  ? 58  GLU B N   1 
ATOM   3020 C CA  . GLU B 2 58  ? 140.131 118.141 177.056 1.00 77.65  ? 58  GLU B CA  1 
ATOM   3021 C C   . GLU B 2 58  ? 138.855 117.995 177.869 1.00 77.65  ? 58  GLU B C   1 
ATOM   3022 O O   . GLU B 2 58  ? 138.751 118.577 178.959 1.00 77.65  ? 58  GLU B O   1 
ATOM   3023 C CB  . GLU B 2 58  ? 141.371 118.050 177.949 1.00 77.65  ? 58  GLU B CB  1 
ATOM   3024 C CG  . GLU B 2 58  ? 141.663 116.673 178.528 1.00 77.65  ? 58  GLU B CG  1 
ATOM   3025 C CD  . GLU B 2 58  ? 140.893 116.363 179.787 1.00 77.65  ? 58  GLU B CD  1 
ATOM   3026 O OE1 . GLU B 2 58  ? 140.562 117.308 180.529 1.00 77.65  ? 58  GLU B OE1 1 
ATOM   3027 O OE2 . GLU B 2 58  ? 140.623 115.170 180.038 1.00 77.65  ? 58  GLU B OE2 1 
ATOM   3028 N N   . PRO B 2 59  ? 137.852 117.270 177.377 1.00 76.76  ? 59  PRO B N   1 
ATOM   3029 C CA  . PRO B 2 59  ? 136.536 117.288 178.026 1.00 76.76  ? 59  PRO B CA  1 
ATOM   3030 C C   . PRO B 2 59  ? 136.574 116.704 179.427 1.00 76.76  ? 59  PRO B C   1 
ATOM   3031 O O   . PRO B 2 59  ? 137.277 115.729 179.693 1.00 76.76  ? 59  PRO B O   1 
ATOM   3032 C CB  . PRO B 2 59  ? 135.668 116.438 177.092 1.00 76.76  ? 59  PRO B CB  1 
ATOM   3033 C CG  . PRO B 2 59  ? 136.615 115.633 176.300 1.00 76.76  ? 59  PRO B CG  1 
ATOM   3034 C CD  . PRO B 2 59  ? 137.865 116.430 176.172 1.00 76.76  ? 59  PRO B CD  1 
ATOM   3035 N N   . GLN B 2 60  ? 135.801 117.312 180.320 1.00 79.96  ? 60  GLN B N   1 
ATOM   3036 C CA  . GLN B 2 60  ? 135.529 116.763 181.637 1.00 79.96  ? 60  GLN B CA  1 
ATOM   3037 C C   . GLN B 2 60  ? 134.277 115.894 181.555 1.00 79.96  ? 60  GLN B C   1 
ATOM   3038 O O   . GLN B 2 60  ? 133.832 115.510 180.472 1.00 79.96  ? 60  GLN B O   1 
ATOM   3039 C CB  . GLN B 2 60  ? 135.374 117.880 182.660 1.00 79.96  ? 60  GLN B CB  1 
ATOM   3040 C CG  . GLN B 2 60  ? 136.450 118.938 182.604 1.00 79.96  ? 60  GLN B CG  1 
ATOM   3041 C CD  . GLN B 2 60  ? 137.823 118.392 182.892 1.00 79.96  ? 60  GLN B CD  1 
ATOM   3042 O OE1 . GLN B 2 60  ? 138.248 118.332 184.043 1.00 79.96  ? 60  GLN B OE1 1 
ATOM   3043 N NE2 . GLN B 2 60  ? 138.535 118.000 181.847 1.00 79.96  ? 60  GLN B NE2 1 
ATOM   3044 N N   . SER B 2 61  ? 133.691 115.576 182.702 1.00 83.39  ? 61  SER B N   1 
ATOM   3045 C CA  . SER B 2 61  ? 132.495 114.741 182.746 1.00 83.39  ? 61  SER B CA  1 
ATOM   3046 C C   . SER B 2 61  ? 131.280 115.583 182.374 1.00 83.39  ? 61  SER B C   1 
ATOM   3047 O O   . SER B 2 61  ? 130.818 116.410 183.160 1.00 83.39  ? 61  SER B O   1 
ATOM   3048 C CB  . SER B 2 61  ? 132.331 114.125 184.129 1.00 83.39  ? 61  SER B CB  1 
ATOM   3049 O OG  . SER B 2 61  ? 132.078 115.125 185.098 1.00 83.39  ? 61  SER B OG  1 
ATOM   3050 N N   . GLY B 2 62  ? 130.755 115.370 181.172 1.00 81.83  ? 62  GLY B N   1 
ATOM   3051 C CA  . GLY B 2 62  ? 129.531 116.029 180.759 1.00 81.83  ? 62  GLY B CA  1 
ATOM   3052 C C   . GLY B 2 62  ? 129.707 116.953 179.575 1.00 81.83  ? 62  GLY B C   1 
ATOM   3053 O O   . GLY B 2 62  ? 130.493 116.669 178.669 1.00 81.83  ? 62  GLY B O   1 
ATOM   3054 N N   . SER B 2 63  ? 128.975 118.064 179.569 1.00 76.66  ? 63  SER B N   1 
ATOM   3055 C CA  . SER B 2 63  ? 129.139 119.103 178.564 1.00 76.66  ? 63  SER B CA  1 
ATOM   3056 C C   . SER B 2 63  ? 130.236 120.084 178.936 1.00 76.66  ? 63  SER B C   1 
ATOM   3057 O O   . SER B 2 63  ? 130.471 121.046 178.203 1.00 76.66  ? 63  SER B O   1 
ATOM   3058 C CB  . SER B 2 63  ? 127.825 119.850 178.354 1.00 76.66  ? 63  SER B CB  1 
ATOM   3059 O OG  . SER B 2 63  ? 127.392 120.437 179.563 1.00 76.66  ? 63  SER B OG  1 
ATOM   3060 N N   . VAL B 2 64  ? 130.907 119.858 180.056 1.00 73.43  ? 64  VAL B N   1 
ATOM   3061 C CA  . VAL B 2 64  ? 131.988 120.712 180.518 1.00 73.43  ? 64  VAL B CA  1 
ATOM   3062 C C   . VAL B 2 64  ? 133.289 120.237 179.896 1.00 73.43  ? 64  VAL B C   1 
ATOM   3063 O O   . VAL B 2 64  ? 133.599 119.042 179.928 1.00 73.43  ? 64  VAL B O   1 
ATOM   3064 C CB  . VAL B 2 64  ? 132.077 120.692 182.049 1.00 73.43  ? 64  VAL B CB  1 
ATOM   3065 C CG1 . VAL B 2 64  ? 133.144 121.636 182.528 1.00 73.43  ? 64  VAL B CG1 1 
ATOM   3066 C CG2 . VAL B 2 64  ? 130.745 121.052 182.640 1.00 73.43  ? 64  VAL B CG2 1 
ATOM   3067 N N   . ILE B 2 65  ? 134.049 121.165 179.326 1.00 68.81  ? 65  ILE B N   1 
ATOM   3068 C CA  . ILE B 2 65  ? 135.360 120.868 178.767 1.00 68.81  ? 65  ILE B CA  1 
ATOM   3069 C C   . ILE B 2 65  ? 136.364 121.848 179.347 1.00 68.81  ? 65  ILE B C   1 
ATOM   3070 O O   . ILE B 2 65  ? 135.987 122.825 180.000 1.00 68.81  ? 65  ILE B O   1 
ATOM   3071 C CB  . ILE B 2 65  ? 135.367 120.934 177.229 1.00 68.81  ? 65  ILE B CB  1 
ATOM   3072 C CG1 . ILE B 2 65  ? 135.494 122.369 176.759 1.00 68.81  ? 65  ILE B CG1 1 
ATOM   3073 C CG2 . ILE B 2 65  ? 134.111 120.333 176.660 1.00 68.81  ? 65  ILE B CG2 1 
ATOM   3074 C CD1 . ILE B 2 65  ? 135.617 122.489 175.277 1.00 68.81  ? 65  ILE B CD1 1 
ATOM   3075 N N   . LYS B 2 66  ? 137.643 121.572 179.134 1.00 68.72  ? 66  LYS B N   1 
ATOM   3076 C CA  . LYS B 2 66  ? 138.714 122.468 179.541 1.00 68.72  ? 66  LYS B CA  1 
ATOM   3077 C C   . LYS B 2 66  ? 139.451 122.935 178.297 1.00 68.72  ? 66  LYS B C   1 
ATOM   3078 O O   . LYS B 2 66  ? 139.772 122.124 177.426 1.00 68.72  ? 66  LYS B O   1 
ATOM   3079 C CB  . LYS B 2 66  ? 139.672 121.768 180.499 1.00 68.72  ? 66  LYS B CB  1 
ATOM   3080 C CG  . LYS B 2 66  ? 140.779 122.655 181.003 1.00 68.72  ? 66  LYS B CG  1 
ATOM   3081 C CD  . LYS B 2 66  ? 141.274 122.201 182.352 1.00 68.72  ? 66  LYS B CD  1 
ATOM   3082 C CE  . LYS B 2 66  ? 142.775 122.302 182.454 1.00 68.72  ? 66  LYS B CE  1 
ATOM   3083 N NZ  . LYS B 2 66  ? 143.215 122.328 183.872 1.00 68.72  ? 66  LYS B NZ  1 
ATOM   3084 N N   . LEU B 2 67  ? 139.708 124.230 178.207 1.00 65.42  ? 67  LEU B N   1 
ATOM   3085 C CA  . LEU B 2 67  ? 140.370 124.811 177.052 1.00 65.42  ? 67  LEU B CA  1 
ATOM   3086 C C   . LEU B 2 67  ? 141.711 125.417 177.426 1.00 65.42  ? 67  LEU B C   1 
ATOM   3087 O O   . LEU B 2 67  ? 141.909 125.895 178.544 1.00 65.42  ? 67  LEU B O   1 
ATOM   3088 C CB  . LEU B 2 67  ? 139.510 125.898 176.418 1.00 65.42  ? 67  LEU B CB  1 
ATOM   3089 C CG  . LEU B 2 67  ? 138.261 125.506 175.664 1.00 65.42  ? 67  LEU B CG  1 
ATOM   3090 C CD1 . LEU B 2 67  ? 137.378 126.707 175.561 1.00 65.42  ? 67  LEU B CD1 1 
ATOM   3091 C CD2 . LEU B 2 67  ? 138.669 125.047 174.292 1.00 65.42  ? 67  LEU B CD2 1 
ATOM   3092 N N   . TRP B 2 68  ? 142.627 125.397 176.468 1.00 68.35  ? 68  TRP B N   1 
ATOM   3093 C CA  . TRP B 2 68  ? 143.828 126.214 176.505 1.00 68.35  ? 68  TRP B CA  1 
ATOM   3094 C C   . TRP B 2 68  ? 144.393 126.258 175.095 1.00 68.35  ? 68  TRP B C   1 
ATOM   3095 O O   . TRP B 2 68  ? 143.800 125.719 174.156 1.00 68.35  ? 68  TRP B O   1 
ATOM   3096 C CB  . TRP B 2 68  ? 144.832 125.690 177.535 1.00 68.35  ? 68  TRP B CB  1 
ATOM   3097 C CG  . TRP B 2 68  ? 145.378 124.346 177.255 1.00 68.35  ? 68  TRP B CG  1 
ATOM   3098 C CD1 . TRP B 2 68  ? 146.385 124.034 176.402 1.00 68.35  ? 68  TRP B CD1 1 
ATOM   3099 C CD2 . TRP B 2 68  ? 144.965 123.121 177.855 1.00 68.35  ? 68  TRP B CD2 1 
ATOM   3100 N NE1 . TRP B 2 68  ? 146.620 122.685 176.420 1.00 68.35  ? 68  TRP B NE1 1 
ATOM   3101 C CE2 . TRP B 2 68  ? 145.757 122.103 177.307 1.00 68.35  ? 68  TRP B CE2 1 
ATOM   3102 C CE3 . TRP B 2 68  ? 143.996 122.786 178.797 1.00 68.35  ? 68  TRP B CE3 1 
ATOM   3103 C CZ2 . TRP B 2 68  ? 145.609 120.775 177.669 1.00 68.35  ? 68  TRP B CZ2 1 
ATOM   3104 C CZ3 . TRP B 2 68  ? 143.851 121.471 179.155 1.00 68.35  ? 68  TRP B CZ3 1 
ATOM   3105 C CH2 . TRP B 2 68  ? 144.652 120.479 178.593 1.00 68.35  ? 68  TRP B CH2 1 
ATOM   3106 N N   . ALA B 2 69  ? 145.535 126.914 174.937 1.00 69.78  ? 69  ALA B N   1 
ATOM   3107 C CA  . ALA B 2 69  ? 146.178 127.027 173.642 1.00 69.78  ? 69  ALA B CA  1 
ATOM   3108 C C   . ALA B 2 69  ? 147.621 126.577 173.762 1.00 69.78  ? 69  ALA B C   1 
ATOM   3109 O O   . ALA B 2 69  ? 148.248 126.733 174.809 1.00 69.78  ? 69  ALA B O   1 
ATOM   3110 C CB  . ALA B 2 69  ? 146.129 128.451 173.113 1.00 69.78  ? 69  ALA B CB  1 
ATOM   3111 N N   . ARG B 2 70  ? 148.144 126.004 172.684 1.00 72.21  ? 70  ARG B N   1 
ATOM   3112 C CA  . ARG B 2 70  ? 149.521 125.528 172.653 1.00 72.21  ? 70  ARG B CA  1 
ATOM   3113 C C   . ARG B 2 70  ? 150.164 125.909 171.327 1.00 72.21  ? 70  ARG B C   1 
ATOM   3114 O O   . ARG B 2 70  ? 149.768 125.414 170.272 1.00 72.21  ? 70  ARG B O   1 
ATOM   3115 C CB  . ARG B 2 70  ? 149.572 124.013 172.851 1.00 72.21  ? 70  ARG B CB  1 
ATOM   3116 C CG  . ARG B 2 70  ? 150.936 123.487 173.266 1.00 72.21  ? 70  ARG B CG  1 
ATOM   3117 C CD  . ARG B 2 70  ? 151.001 121.972 173.151 1.00 72.21  ? 70  ARG B CD  1 
ATOM   3118 N NE  . ARG B 2 70  ? 152.117 121.535 172.317 1.00 72.21  ? 70  ARG B NE  1 
ATOM   3119 C CZ  . ARG B 2 70  ? 151.978 120.953 171.129 1.00 72.21  ? 70  ARG B CZ  1 
ATOM   3120 N NH1 . ARG B 2 70  ? 150.768 120.737 170.631 1.00 72.21  ? 70  ARG B NH1 1 
ATOM   3121 N NH2 . ARG B 2 70  ? 153.049 120.588 170.439 1.00 72.21  ? 70  ARG B NH2 1 
ATOM   3122 N N   . GLY B 2 71  ? 151.158 126.790 171.382 1.00 69.71  ? 71  GLY B N   1 
ATOM   3123 C CA  . GLY B 2 71  ? 151.825 127.233 170.183 1.00 69.71  ? 71  GLY B CA  1 
ATOM   3124 C C   . GLY B 2 71  ? 153.266 127.560 170.461 1.00 69.71  ? 71  GLY B C   1 
ATOM   3125 O O   . GLY B 2 71  ? 153.840 127.121 171.456 1.00 69.71  ? 71  GLY B O   1 
ATOM   3126 N N   . GLY B 2 72  ? 153.858 128.336 169.564 1.00 70.28  ? 72  GLY B N   1 
ATOM   3127 C CA  . GLY B 2 72  ? 155.236 128.732 169.707 1.00 70.28  ? 72  GLY B CA  1 
ATOM   3128 C C   . GLY B 2 72  ? 155.371 129.980 170.547 1.00 70.28  ? 72  GLY B C   1 
ATOM   3129 O O   . GLY B 2 72  ? 154.460 130.353 171.286 1.00 70.28  ? 72  GLY B O   1 
ATOM   3130 N N   . PRO B 2 73  ? 156.517 130.658 170.454 1.00 69.43  ? 73  PRO B N   1 
ATOM   3131 C CA  . PRO B 2 73  ? 156.671 131.927 171.171 1.00 69.43  ? 73  PRO B CA  1 
ATOM   3132 C C   . PRO B 2 73  ? 155.726 132.996 170.686 1.00 69.43  ? 73  PRO B C   1 
ATOM   3133 O O   . PRO B 2 73  ? 155.555 134.006 171.375 1.00 69.43  ? 73  PRO B O   1 
ATOM   3134 C CB  . PRO B 2 73  ? 158.128 132.317 170.898 1.00 69.43  ? 73  PRO B CB  1 
ATOM   3135 C CG  . PRO B 2 73  ? 158.758 131.124 170.316 1.00 69.43  ? 73  PRO B CG  1 
ATOM   3136 C CD  . PRO B 2 73  ? 157.697 130.342 169.644 1.00 69.43  ? 73  PRO B CD  1 
ATOM   3137 N N   . SER B 2 74  ? 155.123 132.815 169.519 1.00 66.39  ? 74  SER B N   1 
ATOM   3138 C CA  . SER B 2 74  ? 154.165 133.763 168.981 1.00 66.39  ? 74  SER B CA  1 
ATOM   3139 C C   . SER B 2 74  ? 152.804 133.660 169.644 1.00 66.39  ? 74  SER B C   1 
ATOM   3140 O O   . SER B 2 74  ? 151.996 134.580 169.506 1.00 66.39  ? 74  SER B O   1 
ATOM   3141 C CB  . SER B 2 74  ? 154.026 133.545 167.481 1.00 66.39  ? 74  SER B CB  1 
ATOM   3142 O OG  . SER B 2 74  ? 155.260 133.777 166.833 1.00 66.39  ? 74  SER B OG  1 
ATOM   3143 N N   . CYS B 2 75  ? 152.533 132.567 170.354 1.00 67.95  ? 75  CYS B N   1 
ATOM   3144 C CA  . CYS B 2 75  ? 151.280 132.391 171.082 1.00 67.95  ? 75  CYS B CA  1 
ATOM   3145 C C   . CYS B 2 75  ? 151.474 132.940 172.490 1.00 67.95  ? 75  CYS B C   1 
ATOM   3146 O O   . CYS B 2 75  ? 151.635 132.205 173.459 1.00 67.95  ? 75  CYS B O   1 
ATOM   3147 C CB  . CYS B 2 75  ? 150.870 130.929 171.097 1.00 67.95  ? 75  CYS B CB  1 
ATOM   3148 S SG  . CYS B 2 75  ? 149.172 130.638 171.565 1.00 67.95  ? 75  CYS B SG  1 
ATOM   3149 N N   . ASP B 2 76  ? 151.474 134.263 172.588 1.00 63.21  ? 76  ASP B N   1 
ATOM   3150 C CA  . ASP B 2 76  ? 151.559 134.941 173.867 1.00 63.21  ? 76  ASP B CA  1 
ATOM   3151 C C   . ASP B 2 76  ? 150.209 134.903 174.570 1.00 63.21  ? 76  ASP B C   1 
ATOM   3152 O O   . ASP B 2 76  ? 149.236 134.353 174.059 1.00 63.21  ? 76  ASP B O   1 
ATOM   3153 C CB  . ASP B 2 76  ? 152.045 136.365 173.658 1.00 63.21  ? 76  ASP B CB  1 
ATOM   3154 C CG  . ASP B 2 76  ? 151.205 137.113 172.665 1.00 63.21  ? 76  ASP B CG  1 
ATOM   3155 O OD1 . ASP B 2 76  ? 150.310 136.486 172.073 1.00 63.21  ? 76  ASP B OD1 1 
ATOM   3156 O OD2 . ASP B 2 76  ? 151.433 138.321 172.474 1.00 63.21  ? 76  ASP B OD2 1 
ATOM   3157 N N   . LYS B 2 77  ? 150.136 135.511 175.755 1.00 59.26  ? 77  LYS B N   1 
ATOM   3158 C CA  . LYS B 2 77  ? 148.911 135.432 176.544 1.00 59.26  ? 77  LYS B CA  1 
ATOM   3159 C C   . LYS B 2 77  ? 147.722 136.032 175.814 1.00 59.26  ? 77  LYS B C   1 
ATOM   3160 O O   . LYS B 2 77  ? 146.590 135.576 175.999 1.00 59.26  ? 77  LYS B O   1 
ATOM   3161 C CB  . LYS B 2 77  ? 149.102 136.118 177.886 1.00 59.26  ? 77  LYS B CB  1 
ATOM   3162 C CG  . LYS B 2 77  ? 149.834 135.268 178.873 1.00 59.26  ? 77  LYS B CG  1 
ATOM   3163 C CD  . LYS B 2 77  ? 150.063 136.008 180.151 1.00 59.26  ? 77  LYS B CD  1 
ATOM   3164 C CE  . LYS B 2 77  ? 149.992 135.076 181.324 1.00 59.26  ? 77  LYS B CE  1 
ATOM   3165 N NZ  . LYS B 2 77  ? 149.824 135.833 182.584 1.00 59.26  ? 77  LYS B NZ  1 
ATOM   3166 N N   . ARG B 2 78  ? 147.946 137.041 174.981 1.00 57.67  ? 78  ARG B N   1 
ATOM   3167 C CA  . ARG B 2 78  ? 146.843 137.602 174.213 1.00 57.67  ? 78  ARG B CA  1 
ATOM   3168 C C   . ARG B 2 78  ? 146.308 136.598 173.206 1.00 57.67  ? 78  ARG B C   1 
ATOM   3169 O O   . ARG B 2 78  ? 145.095 136.484 173.018 1.00 57.67  ? 78  ARG B O   1 
ATOM   3170 C CB  . ARG B 2 78  ? 147.291 138.877 173.513 1.00 57.67  ? 78  ARG B CB  1 
ATOM   3171 C CG  . ARG B 2 78  ? 146.282 139.427 172.555 1.00 57.67  ? 78  ARG B CG  1 
ATOM   3172 C CD  . ARG B 2 78  ? 146.665 140.815 172.149 1.00 57.67  ? 78  ARG B CD  1 
ATOM   3173 N NE  . ARG B 2 78  ? 147.630 140.798 171.064 1.00 57.67  ? 78  ARG B NE  1 
ATOM   3174 C CZ  . ARG B 2 78  ? 147.689 141.720 170.116 1.00 57.67  ? 78  ARG B CZ  1 
ATOM   3175 N NH1 . ARG B 2 78  ? 146.850 142.740 170.135 1.00 57.67  ? 78  ARG B NH1 1 
ATOM   3176 N NH2 . ARG B 2 78  ? 148.600 141.635 169.163 1.00 57.67  ? 78  ARG B NH2 1 
ATOM   3177 N N   . GLY B 2 79  ? 147.194 135.860 172.547 1.00 56.88  ? 79  GLY B N   1 
ATOM   3178 C CA  . GLY B 2 79  ? 146.738 134.852 171.607 1.00 56.88  ? 79  GLY B CA  1 
ATOM   3179 C C   . GLY B 2 79  ? 145.986 133.729 172.285 1.00 56.88  ? 79  GLY B C   1 
ATOM   3180 O O   . GLY B 2 79  ? 144.970 133.253 171.775 1.00 56.88  ? 79  GLY B O   1 
ATOM   3181 N N   . GLU B 2 80  ? 146.469 133.294 173.447 1.00 60.41  ? 80  GLU B N   1 
ATOM   3182 C CA  . GLU B 2 80  ? 145.755 132.278 174.205 1.00 60.41  ? 80  GLU B CA  1 
ATOM   3183 C C   . GLU B 2 80  ? 144.374 132.763 174.603 1.00 60.41  ? 80  GLU B C   1 
ATOM   3184 O O   . GLU B 2 80  ? 143.387 132.041 174.439 1.00 60.41  ? 80  GLU B O   1 
ATOM   3185 C CB  . GLU B 2 80  ? 146.550 131.892 175.445 1.00 60.41  ? 80  GLU B CB  1 
ATOM   3186 C CG  . GLU B 2 80  ? 148.022 131.739 175.214 1.00 60.41  ? 80  GLU B CG  1 
ATOM   3187 C CD  . GLU B 2 80  ? 148.721 131.142 176.405 1.00 60.41  ? 80  GLU B CD  1 
ATOM   3188 O OE1 . GLU B 2 80  ? 148.065 130.982 177.447 1.00 60.41  ? 80  GLU B OE1 1 
ATOM   3189 O OE2 . GLU B 2 80  ? 149.926 130.845 176.311 1.00 60.41  ? 80  GLU B OE2 1 
ATOM   3190 N N   . TYR B 2 81  ? 144.279 133.984 175.122 1.00 55.46  ? 81  TYR B N   1 
ATOM   3191 C CA  . TYR B 2 81  ? 142.977 134.512 175.509 1.00 55.46  ? 81  TYR B CA  1 
ATOM   3192 C C   . TYR B 2 81  ? 142.042 134.606 174.316 1.00 55.46  ? 81  TYR B C   1 
ATOM   3193 O O   . TYR B 2 81  ? 140.873 134.219 174.407 1.00 55.46  ? 81  TYR B O   1 
ATOM   3194 C CB  . TYR B 2 81  ? 143.141 135.879 176.157 1.00 55.46  ? 81  TYR B CB  1 
ATOM   3195 C CG  . TYR B 2 81  ? 141.929 136.350 176.902 1.00 55.46  ? 81  TYR B CG  1 
ATOM   3196 C CD1 . TYR B 2 81  ? 140.959 137.104 176.277 1.00 55.46  ? 81  TYR B CD1 1 
ATOM   3197 C CD2 . TYR B 2 81  ? 141.759 136.049 178.234 1.00 55.46  ? 81  TYR B CD2 1 
ATOM   3198 C CE1 . TYR B 2 81  ? 139.856 137.538 176.958 1.00 55.46  ? 81  TYR B CE1 1 
ATOM   3199 C CE2 . TYR B 2 81  ? 140.660 136.481 178.921 1.00 55.46  ? 81  TYR B CE2 1 
ATOM   3200 C CZ  . TYR B 2 81  ? 139.712 137.223 178.280 1.00 55.46  ? 81  TYR B CZ  1 
ATOM   3201 O OH  . TYR B 2 81  ? 138.609 137.652 178.973 1.00 55.46  ? 81  TYR B OH  1 
ATOM   3202 N N   . LYS B 2 82  ? 142.529 135.116 173.188 1.00 52.27  ? 82  LYS B N   1 
ATOM   3203 C CA  . LYS B 2 82  ? 141.665 135.252 172.024 1.00 52.27  ? 82  LYS B CA  1 
ATOM   3204 C C   . LYS B 2 82  ? 141.173 133.903 171.536 1.00 52.27  ? 82  LYS B C   1 
ATOM   3205 O O   . LYS B 2 82  ? 139.996 133.753 171.204 1.00 52.27  ? 82  LYS B O   1 
ATOM   3206 C CB  . LYS B 2 82  ? 142.389 135.980 170.902 1.00 52.27  ? 82  LYS B CB  1 
ATOM   3207 C CG  . LYS B 2 82  ? 142.641 137.431 171.166 1.00 52.27  ? 82  LYS B CG  1 
ATOM   3208 C CD  . LYS B 2 82  ? 142.536 138.212 169.885 1.00 52.27  ? 82  LYS B CD  1 
ATOM   3209 C CE  . LYS B 2 82  ? 143.569 137.764 168.896 1.00 52.27  ? 82  LYS B CE  1 
ATOM   3210 N NZ  . LYS B 2 82  ? 143.549 138.605 167.681 1.00 52.27  ? 82  LYS B NZ  1 
ATOM   3211 N N   . THR B 2 83  ? 142.052 132.903 171.480 1.00 53.09  ? 83  THR B N   1 
ATOM   3212 C CA  . THR B 2 83  ? 141.616 131.620 170.948 1.00 53.09  ? 83  THR B CA  1 
ATOM   3213 C C   . THR B 2 83  ? 140.676 130.915 171.915 1.00 53.09  ? 83  THR B C   1 
ATOM   3214 O O   . THR B 2 83  ? 139.720 130.256 171.489 1.00 53.09  ? 83  THR B O   1 
ATOM   3215 C CB  . THR B 2 83  ? 142.818 130.747 170.601 1.00 53.09  ? 83  THR B CB  1 
ATOM   3216 O OG1 . THR B 2 83  ? 142.397 129.681 169.750 1.00 53.09  ? 83  THR B OG1 1 
ATOM   3217 C CG2 . THR B 2 83  ? 143.422 130.159 171.823 1.00 53.09  ? 83  THR B CG2 1 
ATOM   3218 N N   . ILE B 2 84  ? 140.894 131.076 173.219 1.00 52.82  ? 84  ILE B N   1 
ATOM   3219 C CA  . ILE B 2 84  ? 139.978 130.499 174.192 1.00 52.82  ? 84  ILE B CA  1 
ATOM   3220 C C   . ILE B 2 84  ? 138.601 131.127 174.068 1.00 52.82  ? 84  ILE B C   1 
ATOM   3221 O O   . ILE B 2 84  ? 137.584 130.428 174.038 1.00 52.82  ? 84  ILE B O   1 
ATOM   3222 C CB  . ILE B 2 84  ? 140.540 130.656 175.611 1.00 52.82  ? 84  ILE B CB  1 
ATOM   3223 C CG1 . ILE B 2 84  ? 141.726 129.727 175.825 1.00 52.82  ? 84  ILE B CG1 1 
ATOM   3224 C CG2 . ILE B 2 84  ? 139.471 130.447 176.619 1.00 52.82  ? 84  ILE B CG2 1 
ATOM   3225 C CD1 . ILE B 2 84  ? 142.454 129.993 177.096 1.00 52.82  ? 84  ILE B CD1 1 
ATOM   3226 N N   . VAL B 2 85  ? 138.544 132.457 174.002 1.00 53.12  ? 85  VAL B N   1 
ATOM   3227 C CA  . VAL B 2 85  ? 137.255 133.128 173.870 1.00 53.12  ? 85  VAL B CA  1 
ATOM   3228 C C   . VAL B 2 85  ? 136.565 132.710 172.584 1.00 53.12  ? 85  VAL B C   1 
ATOM   3229 O O   . VAL B 2 85  ? 135.347 132.507 172.557 1.00 53.12  ? 85  VAL B O   1 
ATOM   3230 C CB  . VAL B 2 85  ? 137.436 134.649 173.944 1.00 53.12  ? 85  VAL B CB  1 
ATOM   3231 C CG1 . VAL B 2 85  ? 136.164 135.338 173.553 1.00 53.12  ? 85  VAL B CG1 1 
ATOM   3232 C CG2 . VAL B 2 85  ? 137.812 135.038 175.334 1.00 53.12  ? 85  VAL B CG2 1 
ATOM   3233 N N   . LYS B 2 86  ? 137.320 132.585 171.498 1.00 56.28  ? 86  LYS B N   1 
ATOM   3234 C CA  . LYS B 2 86  ? 136.717 132.169 170.242 1.00 56.28  ? 86  LYS B CA  1 
ATOM   3235 C C   . LYS B 2 86  ? 136.095 130.791 170.374 1.00 56.28  ? 86  LYS B C   1 
ATOM   3236 O O   . LYS B 2 86  ? 134.960 130.569 169.947 1.00 56.28  ? 86  LYS B O   1 
ATOM   3237 C CB  . LYS B 2 86  ? 137.766 132.182 169.141 1.00 56.28  ? 86  LYS B CB  1 
ATOM   3238 C CG  . LYS B 2 86  ? 137.204 132.176 167.760 1.00 56.28  ? 86  LYS B CG  1 
ATOM   3239 C CD  . LYS B 2 86  ? 138.017 133.079 166.865 1.00 56.28  ? 86  LYS B CD  1 
ATOM   3240 C CE  . LYS B 2 86  ? 139.469 132.646 166.827 1.00 56.28  ? 86  LYS B CE  1 
ATOM   3241 N NZ  . LYS B 2 86  ? 139.611 131.204 166.504 1.00 56.28  ? 86  LYS B NZ  1 
ATOM   3242 N N   . ARG B 2 87  ? 136.816 129.853 170.987 1.00 59.38  ? 87  ARG B N   1 
ATOM   3243 C CA  . ARG B 2 87  ? 136.258 128.516 171.160 1.00 59.38  ? 87  ARG B CA  1 
ATOM   3244 C C   . ARG B 2 87  ? 135.008 128.550 172.024 1.00 59.38  ? 87  ARG B C   1 
ATOM   3245 O O   . ARG B 2 87  ? 134.014 127.885 171.718 1.00 59.38  ? 87  ARG B O   1 
ATOM   3246 C CB  . ARG B 2 87  ? 137.297 127.584 171.772 1.00 59.38  ? 87  ARG B CB  1 
ATOM   3247 C CG  . ARG B 2 87  ? 138.351 127.113 170.807 1.00 59.38  ? 87  ARG B CG  1 
ATOM   3248 C CD  . ARG B 2 87  ? 137.732 126.339 169.679 1.00 59.38  ? 87  ARG B CD  1 
ATOM   3249 N NE  . ARG B 2 87  ? 137.636 127.141 168.470 1.00 59.38  ? 87  ARG B NE  1 
ATOM   3250 C CZ  . ARG B 2 87  ? 136.759 126.914 167.505 1.00 59.38  ? 87  ARG B CZ  1 
ATOM   3251 N NH1 . ARG B 2 87  ? 135.904 125.911 167.615 1.00 59.38  ? 87  ARG B NH1 1 
ATOM   3252 N NH2 . ARG B 2 87  ? 136.736 127.686 166.433 1.00 59.38  ? 87  ARG B NH2 1 
ATOM   3253 N N   . ILE B 2 88  ? 135.037 129.329 173.105 1.00 57.13  ? 88  ILE B N   1 
ATOM   3254 C CA  . ILE B 2 88  ? 133.902 129.381 174.021 1.00 57.13  ? 88  ILE B CA  1 
ATOM   3255 C C   . ILE B 2 88  ? 132.672 129.936 173.325 1.00 57.13  ? 88  ILE B C   1 
ATOM   3256 O O   . ILE B 2 88  ? 131.571 129.396 173.459 1.00 57.13  ? 88  ILE B O   1 
ATOM   3257 C CB  . ILE B 2 88  ? 134.258 130.212 175.261 1.00 57.13  ? 88  ILE B CB  1 
ATOM   3258 C CG1 . ILE B 2 88  ? 135.091 129.392 176.231 1.00 57.13  ? 88  ILE B CG1 1 
ATOM   3259 C CG2 . ILE B 2 88  ? 133.010 130.698 175.935 1.00 57.13  ? 88  ILE B CG2 1 
ATOM   3260 C CD1 . ILE B 2 88  ? 135.474 130.150 177.464 1.00 57.13  ? 88  ILE B CD1 1 
ATOM   3261 N N   . THR B 2 89  ? 132.828 131.019 172.580 1.00 56.66  ? 89  THR B N   1 
ATOM   3262 C CA  . THR B 2 89  ? 131.673 131.646 171.957 1.00 56.66  ? 89  THR B CA  1 
ATOM   3263 C C   . THR B 2 89  ? 131.330 131.059 170.602 1.00 56.66  ? 89  THR B C   1 
ATOM   3264 O O   . THR B 2 89  ? 130.377 131.521 169.972 1.00 56.66  ? 89  THR B O   1 
ATOM   3265 C CB  . THR B 2 89  ? 131.895 133.146 171.793 1.00 56.66  ? 89  THR B CB  1 
ATOM   3266 O OG1 . THR B 2 89  ? 132.881 133.367 170.784 1.00 56.66  ? 89  THR B OG1 1 
ATOM   3267 C CG2 . THR B 2 89  ? 132.361 133.756 173.089 1.00 56.66  ? 89  THR B CG2 1 
ATOM   3268 N N   . ARG B 2 90  ? 132.079 130.072 170.121 1.00 59.32  ? 90  ARG B N   1 
ATOM   3269 C CA  . ARG B 2 90  ? 131.781 129.500 168.824 1.00 59.32  ? 90  ARG B CA  1 
ATOM   3270 C C   . ARG B 2 90  ? 131.392 128.032 168.864 1.00 59.32  ? 90  ARG B C   1 
ATOM   3271 O O   . ARG B 2 90  ? 130.711 127.573 167.945 1.00 59.32  ? 90  ARG B O   1 
ATOM   3272 C CB  . ARG B 2 90  ? 132.986 129.674 167.898 1.00 59.32  ? 90  ARG B CB  1 
ATOM   3273 C CG  . ARG B 2 90  ? 132.650 129.712 166.448 1.00 59.32  ? 90  ARG B CG  1 
ATOM   3274 C CD  . ARG B 2 90  ? 133.817 130.243 165.670 1.00 59.32  ? 90  ARG B CD  1 
ATOM   3275 N NE  . ARG B 2 90  ? 133.997 131.665 165.906 1.00 59.32  ? 90  ARG B NE  1 
ATOM   3276 C CZ  . ARG B 2 90  ? 134.752 132.446 165.150 1.00 59.32  ? 90  ARG B CZ  1 
ATOM   3277 N NH1 . ARG B 2 90  ? 135.402 131.934 164.120 1.00 59.32  ? 90  ARG B NH1 1 
ATOM   3278 N NH2 . ARG B 2 90  ? 134.865 133.732 165.428 1.00 59.32  ? 90  ARG B NH2 1 
ATOM   3279 N N   . ASP B 2 91  ? 131.799 127.285 169.886 1.00 68.51  ? 91  ASP B N   1 
ATOM   3280 C CA  . ASP B 2 91  ? 131.407 125.889 170.004 1.00 68.51  ? 91  ASP B CA  1 
ATOM   3281 C C   . ASP B 2 91  ? 130.169 125.678 170.858 1.00 68.51  ? 91  ASP B C   1 
ATOM   3282 O O   . ASP B 2 91  ? 129.687 124.546 170.948 1.00 68.51  ? 91  ASP B O   1 
ATOM   3283 C CB  . ASP B 2 91  ? 132.554 125.058 170.582 1.00 68.51  ? 91  ASP B CB  1 
ATOM   3284 C CG  . ASP B 2 91  ? 133.668 124.841 169.589 1.00 68.51  ? 91  ASP B CG  1 
ATOM   3285 O OD1 . ASP B 2 91  ? 133.522 125.286 168.433 1.00 68.51  ? 91  ASP B OD1 1 
ATOM   3286 O OD2 . ASP B 2 91  ? 134.684 124.217 169.956 1.00 68.51  ? 91  ASP B OD2 1 
ATOM   3287 N N   . TYR B 2 92  ? 129.647 126.723 171.483 1.00 69.61  ? 92  TYR B N   1 
ATOM   3288 C CA  . TYR B 2 92  ? 128.513 126.616 172.386 1.00 69.61  ? 92  TYR B CA  1 
ATOM   3289 C C   . TYR B 2 92  ? 127.433 127.590 171.952 1.00 69.61  ? 92  TYR B C   1 
ATOM   3290 O O   . TYR B 2 92  ? 127.720 128.760 171.694 1.00 69.61  ? 92  TYR B O   1 
ATOM   3291 C CB  . TYR B 2 92  ? 128.945 126.896 173.818 1.00 69.61  ? 92  TYR B CB  1 
ATOM   3292 C CG  . TYR B 2 92  ? 129.753 125.781 174.417 1.00 69.61  ? 92  TYR B CG  1 
ATOM   3293 C CD1 . TYR B 2 92  ? 129.204 124.937 175.356 1.00 69.61  ? 92  TYR B CD1 1 
ATOM   3294 C CD2 . TYR B 2 92  ? 131.055 125.558 174.027 1.00 69.61  ? 92  TYR B CD2 1 
ATOM   3295 C CE1 . TYR B 2 92  ? 129.922 123.918 175.898 1.00 69.61  ? 92  TYR B CE1 1 
ATOM   3296 C CE2 . TYR B 2 92  ? 131.781 124.537 174.563 1.00 69.61  ? 92  TYR B CE2 1 
ATOM   3297 C CZ  . TYR B 2 92  ? 131.207 123.719 175.498 1.00 69.61  ? 92  TYR B CZ  1 
ATOM   3298 O OH  . TYR B 2 92  ? 131.924 122.691 176.045 1.00 69.61  ? 92  TYR B OH  1 
ATOM   3299 N N   . GLU B 2 93  ? 126.196 127.108 171.873 1.00 78.95  ? 93  GLU B N   1 
ATOM   3300 C CA  . GLU B 2 93  ? 125.102 127.935 171.398 1.00 78.95  ? 93  GLU B CA  1 
ATOM   3301 C C   . GLU B 2 93  ? 124.261 128.389 172.576 1.00 78.95  ? 93  GLU B C   1 
ATOM   3302 O O   . GLU B 2 93  ? 123.557 127.566 173.172 1.00 78.95  ? 93  GLU B O   1 
ATOM   3303 C CB  . GLU B 2 93  ? 124.246 127.165 170.401 1.00 78.95  ? 93  GLU B CB  1 
ATOM   3304 C CG  . GLU B 2 93  ? 123.099 127.967 169.817 1.00 78.95  ? 93  GLU B CG  1 
ATOM   3305 C CD  . GLU B 2 93  ? 123.556 129.135 168.964 1.00 78.95  ? 93  GLU B CD  1 
ATOM   3306 O OE1 . GLU B 2 93  ? 124.675 129.074 168.415 1.00 78.95  ? 93  GLU B OE1 1 
ATOM   3307 O OE2 . GLU B 2 93  ? 122.792 130.112 168.837 1.00 78.95  ? 93  GLU B OE2 1 
ATOM   3308 N N   . PRO B 2 94  ? 124.283 129.670 172.943 1.00 75.60  ? 94  PRO B N   1 
ATOM   3309 C CA  . PRO B 2 94  ? 123.497 130.134 174.087 1.00 75.60  ? 94  PRO B CA  1 
ATOM   3310 C C   . PRO B 2 94  ? 122.029 130.367 173.783 1.00 75.60  ? 94  PRO B C   1 
ATOM   3311 O O   . PRO B 2 94  ? 121.266 130.661 174.709 1.00 75.60  ? 94  PRO B O   1 
ATOM   3312 C CB  . PRO B 2 94  ? 124.186 131.449 174.452 1.00 75.60  ? 94  PRO B CB  1 
ATOM   3313 C CG  . PRO B 2 94  ? 124.694 131.950 173.177 1.00 75.60  ? 94  PRO B CG  1 
ATOM   3314 C CD  . PRO B 2 94  ? 125.061 130.757 172.340 1.00 75.60  ? 94  PRO B CD  1 
ATOM   3315 N N   . ASN B 2 95  ? 121.614 130.276 172.524 1.00 81.10  ? 95  ASN B N   1 
ATOM   3316 C CA  . ASN B 2 95  ? 120.204 130.336 172.179 1.00 81.10  ? 95  ASN B CA  1 
ATOM   3317 C C   . ASN B 2 95  ? 119.509 128.996 172.352 1.00 81.10  ? 95  ASN B C   1 
ATOM   3318 O O   . ASN B 2 95  ? 118.278 128.948 172.356 1.00 81.10  ? 95  ASN B O   1 
ATOM   3319 C CB  . ASN B 2 95  ? 120.029 130.824 170.742 1.00 81.10  ? 95  ASN B CB  1 
ATOM   3320 C CG  . ASN B 2 95  ? 120.773 132.108 170.471 1.00 81.10  ? 95  ASN B CG  1 
ATOM   3321 O OD1 . ASN B 2 95  ? 120.307 133.192 170.811 1.00 81.10  ? 95  ASN B OD1 1 
ATOM   3322 N ND2 . ASN B 2 95  ? 121.930 131.995 169.846 1.00 81.10  ? 95  ASN B ND2 1 
ATOM   3323 N N   . ASP B 2 96  ? 120.268 127.914 172.495 1.00 83.44  ? 96  ASP B N   1 
ATOM   3324 C CA  . ASP B 2 96  ? 119.694 126.611 172.792 1.00 83.44  ? 96  ASP B CA  1 
ATOM   3325 C C   . ASP B 2 96  ? 119.523 126.471 174.294 1.00 83.44  ? 96  ASP B C   1 
ATOM   3326 O O   . ASP B 2 96  ? 118.418 126.215 174.779 1.00 83.44  ? 96  ASP B O   1 
ATOM   3327 C CB  . ASP B 2 96  ? 120.582 125.507 172.234 1.00 83.44  ? 96  ASP B CB  1 
ATOM   3328 C CG  . ASP B 2 96  ? 120.717 125.587 170.737 1.00 83.44  ? 96  ASP B CG  1 
ATOM   3329 O OD1 . ASP B 2 96  ? 120.263 126.598 170.165 1.00 83.44  ? 96  ASP B OD1 1 
ATOM   3330 O OD2 . ASP B 2 96  ? 121.278 124.651 170.133 1.00 83.44  ? 96  ASP B OD2 1 
ATOM   3331 N N   . GLU B 2 97  ? 120.611 126.636 175.035 1.00 80.05  ? 97  GLU B N   1 
ATOM   3332 C CA  . GLU B 2 97  ? 120.543 126.844 176.470 1.00 80.05  ? 97  GLU B CA  1 
ATOM   3333 C C   . GLU B 2 97  ? 121.748 127.651 176.917 1.00 80.05  ? 97  GLU B C   1 
ATOM   3334 O O   . GLU B 2 97  ? 122.761 127.735 176.225 1.00 80.05  ? 97  GLU B O   1 
ATOM   3335 C CB  . GLU B 2 97  ? 120.452 125.533 177.249 1.00 80.05  ? 97  GLU B CB  1 
ATOM   3336 C CG  . GLU B 2 97  ? 121.647 124.634 177.168 1.00 80.05  ? 97  GLU B CG  1 
ATOM   3337 C CD  . GLU B 2 97  ? 121.402 123.355 177.928 1.00 80.05  ? 97  GLU B CD  1 
ATOM   3338 O OE1 . GLU B 2 97  ? 120.291 123.215 178.472 1.00 80.05  ? 97  GLU B OE1 1 
ATOM   3339 O OE2 . GLU B 2 97  ? 122.296 122.492 177.990 1.00 80.05  ? 97  GLU B OE2 1 
ATOM   3340 N N   . HIS B 2 98  ? 121.615 128.260 178.085 1.00 75.47  ? 98  HIS B N   1 
ATOM   3341 C CA  . HIS B 2 98  ? 122.576 129.252 178.535 1.00 75.47  ? 98  HIS B CA  1 
ATOM   3342 C C   . HIS B 2 98  ? 123.801 128.567 179.113 1.00 75.47  ? 98  HIS B C   1 
ATOM   3343 O O   . HIS B 2 98  ? 123.684 127.661 179.941 1.00 75.47  ? 98  HIS B O   1 
ATOM   3344 C CB  . HIS B 2 98  ? 121.933 130.173 179.563 1.00 75.47  ? 98  HIS B CB  1 
ATOM   3345 C CG  . HIS B 2 98  ? 120.828 131.005 179.004 1.00 75.47  ? 98  HIS B CG  1 
ATOM   3346 N ND1 . HIS B 2 98  ? 120.909 131.602 177.766 1.00 75.47  ? 98  HIS B ND1 1 
ATOM   3347 C CD2 . HIS B 2 98  ? 119.618 131.336 179.506 1.00 75.47  ? 98  HIS B CD2 1 
ATOM   3348 C CE1 . HIS B 2 98  ? 119.793 132.268 177.529 1.00 75.47  ? 98  HIS B CE1 1 
ATOM   3349 N NE2 . HIS B 2 98  ? 118.994 132.122 178.570 1.00 75.47  ? 98  HIS B NE2 1 
ATOM   3350 N N   . LEU B 2 99  ? 124.973 129.001 178.673 1.00 68.65  ? 99  LEU B N   1 
ATOM   3351 C CA  . LEU B 2 99  ? 126.216 128.444 179.161 1.00 68.65  ? 99  LEU B CA  1 
ATOM   3352 C C   . LEU B 2 99  ? 126.838 129.348 180.212 1.00 68.65  ? 99  LEU B C   1 
ATOM   3353 O O   . LEU B 2 99  ? 126.365 130.451 180.481 1.00 68.65  ? 99  LEU B O   1 
ATOM   3354 C CB  . LEU B 2 99  ? 127.202 128.227 178.020 1.00 68.65  ? 99  LEU B CB  1 
ATOM   3355 C CG  . LEU B 2 99  ? 127.867 129.425 177.375 1.00 68.65  ? 99  LEU B CG  1 
ATOM   3356 C CD1 . LEU B 2 99  ? 129.033 128.958 176.586 1.00 68.65  ? 99  LEU B CD1 1 
ATOM   3357 C CD2 . LEU B 2 99  ? 126.888 130.034 176.432 1.00 68.65  ? 99  LEU B CD2 1 
ATOM   3358 N N   . SER B 2 100 ? 127.913 128.853 180.816 1.00 70.24  ? 100 SER B N   1 
ATOM   3359 C CA  . SER B 2 100 ? 128.642 129.595 181.833 1.00 70.24  ? 100 SER B CA  1 
ATOM   3360 C C   . SER B 2 100 ? 130.073 129.095 181.841 1.00 70.24  ? 100 SER B C   1 
ATOM   3361 O O   . SER B 2 100 ? 130.299 127.886 181.904 1.00 70.24  ? 100 SER B O   1 
ATOM   3362 C CB  . SER B 2 100 ? 128.012 129.415 183.207 1.00 70.24  ? 100 SER B CB  1 
ATOM   3363 O OG  . SER B 2 100 ? 128.210 128.096 183.667 1.00 70.24  ? 100 SER B OG  1 
ATOM   3364 N N   . PHE B 2 101 ? 131.030 130.013 181.791 1.00 68.77  ? 101 PHE B N   1 
ATOM   3365 C CA  . PHE B 2 101 ? 132.436 129.662 181.715 1.00 68.77  ? 101 PHE B CA  1 
ATOM   3366 C C   . PHE B 2 101 ? 133.226 130.441 182.753 1.00 68.77  ? 101 PHE B C   1 
ATOM   3367 O O   . PHE B 2 101 ? 132.675 131.230 183.521 1.00 68.77  ? 101 PHE B O   1 
ATOM   3368 C CB  . PHE B 2 101 ? 133.004 129.938 180.327 1.00 68.77  ? 101 PHE B CB  1 
ATOM   3369 C CG  . PHE B 2 101 ? 132.959 131.376 179.940 1.00 68.77  ? 101 PHE B CG  1 
ATOM   3370 C CD1 . PHE B 2 101 ? 131.796 131.941 179.476 1.00 68.77  ? 101 PHE B CD1 1 
ATOM   3371 C CD2 . PHE B 2 101 ? 134.073 132.168 180.056 1.00 68.77  ? 101 PHE B CD2 1 
ATOM   3372 C CE1 . PHE B 2 101 ? 131.752 133.263 179.133 1.00 68.77  ? 101 PHE B CE1 1 
ATOM   3373 C CE2 . PHE B 2 101 ? 134.026 133.489 179.711 1.00 68.77  ? 101 PHE B CE2 1 
ATOM   3374 C CZ  . PHE B 2 101 ? 132.866 134.034 179.250 1.00 68.77  ? 101 PHE B CZ  1 
ATOM   3375 N N   . CYS B 2 102 ? 134.529 130.201 182.769 1.00 74.05  ? 102 CYS B N   1 
ATOM   3376 C CA  . CYS B 2 102 ? 135.465 130.941 183.600 1.00 74.05  ? 102 CYS B CA  1 
ATOM   3377 C C   . CYS B 2 102 ? 136.831 130.878 182.945 1.00 74.05  ? 102 CYS B C   1 
ATOM   3378 O O   . CYS B 2 102 ? 137.139 129.912 182.245 1.00 74.05  ? 102 CYS B O   1 
ATOM   3379 C CB  . CYS B 2 102 ? 135.549 130.369 185.001 1.00 74.05  ? 102 CYS B CB  1 
ATOM   3380 S SG  . CYS B 2 102 ? 136.547 128.887 185.102 1.00 74.05  ? 102 CYS B SG  1 
ATOM   3381 N N   . ILE B 2 103 ? 137.652 131.896 183.168 1.00 68.43  ? 103 ILE B N   1 
ATOM   3382 C CA  . ILE B 2 103 ? 138.991 131.954 182.594 1.00 68.43  ? 103 ILE B CA  1 
ATOM   3383 C C   . ILE B 2 103 ? 139.983 132.199 183.716 1.00 68.43  ? 103 ILE B C   1 
ATOM   3384 O O   . ILE B 2 103 ? 139.818 133.131 184.508 1.00 68.43  ? 103 ILE B O   1 
ATOM   3385 C CB  . ILE B 2 103 ? 139.095 133.030 181.509 1.00 68.43  ? 103 ILE B CB  1 
ATOM   3386 C CG1 . ILE B 2 103 ? 138.368 132.559 180.260 1.00 68.43  ? 103 ILE B CG1 1 
ATOM   3387 C CG2 . ILE B 2 103 ? 140.528 133.296 181.178 1.00 68.43  ? 103 ILE B CG2 1 
ATOM   3388 C CD1 . ILE B 2 103 ? 138.402 133.536 179.146 1.00 68.43  ? 103 ILE B CD1 1 
ATOM   3389 N N   . ILE B 2 104 ? 141.014 131.364 183.784 1.00 70.66  ? 104 ILE B N   1 
ATOM   3390 C CA  . ILE B 2 104 ? 141.980 131.386 184.872 1.00 70.66  ? 104 ILE B CA  1 
ATOM   3391 C C   . ILE B 2 104 ? 143.347 131.715 184.293 1.00 70.66  ? 104 ILE B C   1 
ATOM   3392 O O   . ILE B 2 104 ? 143.808 131.055 183.356 1.00 70.66  ? 104 ILE B O   1 
ATOM   3393 C CB  . ILE B 2 104 ? 142.013 130.048 185.617 1.00 70.66  ? 104 ILE B CB  1 
ATOM   3394 C CG1 . ILE B 2 104 ? 140.600 129.608 185.969 1.00 70.66  ? 104 ILE B CG1 1 
ATOM   3395 C CG2 . ILE B 2 104 ? 142.840 130.173 186.870 1.00 70.66  ? 104 ILE B CG2 1 
ATOM   3396 C CD1 . ILE B 2 104 ? 140.513 128.170 186.388 1.00 70.66  ? 104 ILE B CD1 1 
ATOM   3397 N N   . GLU B 2 105 ? 143.999 132.723 184.857 1.00 74.76  ? 105 GLU B N   1 
ATOM   3398 C CA  . GLU B 2 105 ? 145.311 133.143 184.399 1.00 74.76  ? 105 GLU B CA  1 
ATOM   3399 C C   . GLU B 2 105 ? 146.389 132.392 185.163 1.00 74.76  ? 105 GLU B C   1 
ATOM   3400 O O   . GLU B 2 105 ? 146.189 131.995 186.312 1.00 74.76  ? 105 GLU B O   1 
ATOM   3401 C CB  . GLU B 2 105 ? 145.494 134.647 184.594 1.00 74.76  ? 105 GLU B CB  1 
ATOM   3402 C CG  . GLU B 2 105 ? 146.804 135.184 184.050 1.00 74.76  ? 105 GLU B CG  1 
ATOM   3403 C CD  . GLU B 2 105 ? 146.948 136.676 184.215 1.00 74.76  ? 105 GLU B CD  1 
ATOM   3404 O OE1 . GLU B 2 105 ? 146.029 137.304 184.777 1.00 74.76  ? 105 GLU B OE1 1 
ATOM   3405 O OE2 . GLU B 2 105 ? 147.984 137.223 183.791 1.00 74.76  ? 105 GLU B OE2 1 
ATOM   3406 N N   . ASN B 2 106 ? 147.532 132.200 184.520 1.00 78.90  ? 106 ASN B N   1 
ATOM   3407 C CA  . ASN B 2 106 ? 148.699 131.608 185.155 1.00 78.90  ? 106 ASN B CA  1 
ATOM   3408 C C   . ASN B 2 106 ? 149.676 132.731 185.477 1.00 78.90  ? 106 ASN B C   1 
ATOM   3409 O O   . ASN B 2 106 ? 150.339 133.259 184.580 1.00 78.90  ? 106 ASN B O   1 
ATOM   3410 C CB  . ASN B 2 106 ? 149.337 130.566 184.246 1.00 78.90  ? 106 ASN B CB  1 
ATOM   3411 C CG  . ASN B 2 106 ? 150.415 129.785 184.937 1.00 78.90  ? 106 ASN B CG  1 
ATOM   3412 O OD1 . ASN B 2 106 ? 150.721 130.023 186.101 1.00 78.90  ? 106 ASN B OD1 1 
ATOM   3413 N ND2 . ASN B 2 106 ? 151.009 128.851 184.223 1.00 78.90  ? 106 ASN B ND2 1 
ATOM   3414 N N   . ASP B 2 107 ? 149.765 133.095 186.753 1.00 84.25  ? 107 ASP B N   1 
ATOM   3415 C CA  . ASP B 2 107 ? 150.550 134.264 187.128 1.00 84.25  ? 107 ASP B CA  1 
ATOM   3416 C C   . ASP B 2 107 ? 152.046 133.987 187.177 1.00 84.25  ? 107 ASP B C   1 
ATOM   3417 O O   . ASP B 2 107 ? 152.841 134.929 187.123 1.00 84.25  ? 107 ASP B O   1 
ATOM   3418 C CB  . ASP B 2 107 ? 150.076 134.799 188.478 1.00 84.25  ? 107 ASP B CB  1 
ATOM   3419 C CG  . ASP B 2 107 ? 148.946 135.796 188.342 1.00 84.25  ? 107 ASP B CG  1 
ATOM   3420 O OD1 . ASP B 2 107 ? 149.011 136.650 187.435 1.00 84.25  ? 107 ASP B OD1 1 
ATOM   3421 O OD2 . ASP B 2 107 ? 147.989 135.724 189.138 1.00 84.25  ? 107 ASP B OD2 1 
ATOM   3422 N N   . ASN B 2 108 ? 152.458 132.726 187.282 1.00 82.43  ? 108 ASN B N   1 
ATOM   3423 C CA  . ASN B 2 108 ? 153.885 132.437 187.355 1.00 82.43  ? 108 ASN B CA  1 
ATOM   3424 C C   . ASN B 2 108 ? 154.474 132.272 185.963 1.00 82.43  ? 108 ASN B C   1 
ATOM   3425 O O   . ASN B 2 108 ? 155.255 131.347 185.721 1.00 82.43  ? 108 ASN B O   1 
ATOM   3426 C CB  . ASN B 2 108 ? 154.131 131.172 188.172 1.00 82.43  ? 108 ASN B CB  1 
ATOM   3427 C CG  . ASN B 2 108 ? 153.271 131.106 189.410 1.00 82.43  ? 108 ASN B CG  1 
ATOM   3428 O OD1 . ASN B 2 108 ? 152.488 130.174 189.586 1.00 82.43  ? 108 ASN B OD1 1 
ATOM   3429 N ND2 . ASN B 2 108 ? 153.411 132.098 190.277 1.00 82.43  ? 108 ASN B ND2 1 
ATOM   3430 N N   . VAL B 2 109 ? 154.149 133.195 185.065 1.00 74.63  ? 109 VAL B N   1 
ATOM   3431 C CA  . VAL B 2 109 ? 154.423 133.084 183.634 1.00 74.63  ? 109 VAL B CA  1 
ATOM   3432 C C   . VAL B 2 109 ? 154.440 134.472 183.006 1.00 74.63  ? 109 VAL B C   1 
ATOM   3433 O O   . VAL B 2 109 ? 153.493 135.245 183.196 1.00 74.63  ? 109 VAL B O   1 
ATOM   3434 C CB  . VAL B 2 109 ? 153.382 132.196 182.934 1.00 74.63  ? 109 VAL B CB  1 
ATOM   3435 C CG1 . VAL B 2 109 ? 153.573 132.272 181.490 1.00 74.63  ? 109 VAL B CG1 1 
ATOM   3436 C CG2 . VAL B 2 109 ? 153.550 130.746 183.314 1.00 74.63  ? 109 VAL B CG2 1 
ATOM   3437 N N   . PRO B 2 110 ? 155.479 134.831 182.259 1.00 70.37  ? 110 PRO B N   1 
ATOM   3438 C CA  . PRO B 2 110 ? 155.485 136.110 181.552 1.00 70.37  ? 110 PRO B CA  1 
ATOM   3439 C C   . PRO B 2 110 ? 154.602 136.048 180.321 1.00 70.37  ? 110 PRO B C   1 
ATOM   3440 O O   . PRO B 2 110 ? 154.178 134.960 179.909 1.00 70.37  ? 110 PRO B O   1 
ATOM   3441 C CB  . PRO B 2 110 ? 156.959 136.282 181.173 1.00 70.37  ? 110 PRO B CB  1 
ATOM   3442 C CG  . PRO B 2 110 ? 157.439 134.891 181.014 1.00 70.37  ? 110 PRO B CG  1 
ATOM   3443 C CD  . PRO B 2 110 ? 156.747 134.105 182.085 1.00 70.37  ? 110 PRO B CD  1 
ATOM   3444 N N   . PRO B 2 111 ? 154.291 137.192 179.708 1.00 66.81  ? 111 PRO B N   1 
ATOM   3445 C CA  . PRO B 2 111 ? 153.373 137.182 178.559 1.00 66.81  ? 111 PRO B CA  1 
ATOM   3446 C C   . PRO B 2 111 ? 153.823 136.336 177.382 1.00 66.81  ? 111 PRO B C   1 
ATOM   3447 O O   . PRO B 2 111 ? 152.969 135.754 176.707 1.00 66.81  ? 111 PRO B O   1 
ATOM   3448 C CB  . PRO B 2 111 ? 153.287 138.664 178.190 1.00 66.81  ? 111 PRO B CB  1 
ATOM   3449 C CG  . PRO B 2 111 ? 153.448 139.342 179.488 1.00 66.81  ? 111 PRO B CG  1 
ATOM   3450 C CD  . PRO B 2 111 ? 154.506 138.556 180.208 1.00 66.81  ? 111 PRO B CD  1 
ATOM   3451 N N   . VAL B 2 112 ? 155.118 136.249 177.096 1.00 67.62  ? 112 VAL B N   1 
ATOM   3452 C CA  . VAL B 2 112 ? 155.632 135.375 176.043 1.00 67.62  ? 112 VAL B CA  1 
ATOM   3453 C C   . VAL B 2 112 ? 156.371 134.239 176.729 1.00 67.62  ? 112 VAL B C   1 
ATOM   3454 O O   . VAL B 2 112 ? 157.401 134.463 177.374 1.00 67.62  ? 112 VAL B O   1 
ATOM   3455 C CB  . VAL B 2 112 ? 156.548 136.114 175.067 1.00 67.62  ? 112 VAL B CB  1 
ATOM   3456 C CG1 . VAL B 2 112 ? 157.150 135.132 174.093 1.00 67.62  ? 112 VAL B CG1 1 
ATOM   3457 C CG2 . VAL B 2 112 ? 155.773 137.184 174.333 1.00 67.62  ? 112 VAL B CG2 1 
ATOM   3458 N N   . HIS B 2 113 ? 155.842 133.020 176.610 1.00 69.50  ? 113 HIS B N   1 
ATOM   3459 C CA  . HIS B 2 113 ? 156.291 131.966 177.508 1.00 69.50  ? 113 HIS B CA  1 
ATOM   3460 C C   . HIS B 2 113 ? 156.363 130.586 176.874 1.00 69.50  ? 113 HIS B C   1 
ATOM   3461 O O   . HIS B 2 113 ? 156.467 129.591 177.597 1.00 69.50  ? 113 HIS B O   1 
ATOM   3462 C CB  . HIS B 2 113 ? 155.370 131.888 178.698 1.00 69.50  ? 113 HIS B CB  1 
ATOM   3463 C CG  . HIS B 2 113 ? 153.958 131.558 178.338 1.00 69.50  ? 113 HIS B CG  1 
ATOM   3464 N ND1 . HIS B 2 113 ? 153.314 130.437 178.807 1.00 69.50  ? 113 HIS B ND1 1 
ATOM   3465 C CD2 . HIS B 2 113 ? 153.058 132.212 177.569 1.00 69.50  ? 113 HIS B CD2 1 
ATOM   3466 C CE1 . HIS B 2 113 ? 152.082 130.410 178.335 1.00 69.50  ? 113 HIS B CE1 1 
ATOM   3467 N NE2 . HIS B 2 113 ? 151.902 131.474 177.578 1.00 69.50  ? 113 HIS B NE2 1 
ATOM   3468 N N   . TYR B 2 114 ? 156.300 130.483 175.557 1.00 72.48  ? 114 TYR B N   1 
ATOM   3469 C CA  . TYR B 2 114 ? 156.441 129.176 174.951 1.00 72.48  ? 114 TYR B CA  1 
ATOM   3470 C C   . TYR B 2 114 ? 157.778 129.006 174.250 1.00 72.48  ? 114 TYR B C   1 
ATOM   3471 O O   . TYR B 2 114 ? 158.110 129.784 173.348 1.00 72.48  ? 114 TYR B O   1 
ATOM   3472 C CB  . TYR B 2 114 ? 155.305 128.869 173.982 1.00 72.48  ? 114 TYR B CB  1 
ATOM   3473 C CG  . TYR B 2 114 ? 154.008 128.490 174.642 1.00 72.48  ? 114 TYR B CG  1 
ATOM   3474 C CD1 . TYR B 2 114 ? 153.970 128.127 175.972 1.00 72.48  ? 114 TYR B CD1 1 
ATOM   3475 C CD2 . TYR B 2 114 ? 152.835 128.421 173.919 1.00 72.48  ? 114 TYR B CD2 1 
ATOM   3476 C CE1 . TYR B 2 114 ? 152.797 127.741 176.566 1.00 72.48  ? 114 TYR B CE1 1 
ATOM   3477 C CE2 . TYR B 2 114 ? 151.663 128.041 174.505 1.00 72.48  ? 114 TYR B CE2 1 
ATOM   3478 C CZ  . TYR B 2 114 ? 151.647 127.704 175.827 1.00 72.48  ? 114 TYR B CZ  1 
ATOM   3479 O OH  . TYR B 2 114 ? 150.470 127.325 176.412 1.00 72.48  ? 114 TYR B OH  1 
ATOM   3480 N N   . PRO B 2 115 ? 158.566 128.012 174.641 1.00 80.07  ? 115 PRO B N   1 
ATOM   3481 C CA  . PRO B 2 115 ? 159.705 127.608 173.819 1.00 80.07  ? 115 PRO B CA  1 
ATOM   3482 C C   . PRO B 2 115 ? 159.230 127.143 172.459 1.00 80.07  ? 115 PRO B C   1 
ATOM   3483 O O   . PRO B 2 115 ? 158.095 126.698 172.291 1.00 80.07  ? 115 PRO B O   1 
ATOM   3484 C CB  . PRO B 2 115 ? 160.334 126.452 174.601 1.00 80.07  ? 115 PRO B CB  1 
ATOM   3485 C CG  . PRO B 2 115 ? 159.719 126.456 175.930 1.00 80.07  ? 115 PRO B CG  1 
ATOM   3486 C CD  . PRO B 2 115 ? 158.547 127.367 175.960 1.00 80.07  ? 115 PRO B CD  1 
ATOM   3487 N N   . ILE B 2 116 ? 160.120 127.261 171.476 1.00 83.56  ? 116 ILE B N   1 
ATOM   3488 C CA  . ILE B 2 116 ? 159.769 126.902 170.113 1.00 83.56  ? 116 ILE B CA  1 
ATOM   3489 C C   . ILE B 2 116 ? 159.441 125.426 169.964 1.00 83.56  ? 116 ILE B C   1 
ATOM   3490 O O   . ILE B 2 116 ? 158.480 125.077 169.272 1.00 83.56  ? 116 ILE B O   1 
ATOM   3491 C CB  . ILE B 2 116 ? 160.913 127.273 169.155 1.00 83.56  ? 116 ILE B CB  1 
ATOM   3492 C CG1 . ILE B 2 116 ? 161.196 128.770 169.217 1.00 83.56  ? 116 ILE B CG1 1 
ATOM   3493 C CG2 . ILE B 2 116 ? 160.568 126.874 167.739 1.00 83.56  ? 116 ILE B CG2 1 
ATOM   3494 C CD1 . ILE B 2 116 ? 162.465 129.171 168.525 1.00 83.56  ? 116 ILE B CD1 1 
ATOM   3495 N N   . HIS B 2 117 ? 160.209 124.541 170.595 1.00 91.14  ? 117 HIS B N   1 
ATOM   3496 C CA  . HIS B 2 117 ? 160.313 123.192 170.060 1.00 91.14  ? 117 HIS B CA  1 
ATOM   3497 C C   . HIS B 2 117 ? 159.216 122.199 170.428 1.00 91.14  ? 117 HIS B C   1 
ATOM   3498 O O   . HIS B 2 117 ? 158.380 121.883 169.577 1.00 91.14  ? 117 HIS B O   1 
ATOM   3499 C CB  . HIS B 2 117 ? 161.680 122.642 170.467 1.00 91.14  ? 117 HIS B CB  1 
ATOM   3500 C CG  . HIS B 2 117 ? 162.010 122.865 171.908 1.00 91.14  ? 117 HIS B CG  1 
ATOM   3501 N ND1 . HIS B 2 117 ? 161.603 122.018 172.913 1.00 91.14  ? 117 HIS B ND1 1 
ATOM   3502 C CD2 . HIS B 2 117 ? 162.684 123.870 172.514 1.00 91.14  ? 117 HIS B CD2 1 
ATOM   3503 C CE1 . HIS B 2 117 ? 162.035 122.476 174.073 1.00 91.14  ? 117 HIS B CE1 1 
ATOM   3504 N NE2 . HIS B 2 117 ? 162.689 123.601 173.860 1.00 91.14  ? 117 HIS B NE2 1 
ATOM   3505 N N   . GLU B 2 118 ? 159.182 121.682 171.656 1.00 95.39  ? 118 GLU B N   1 
ATOM   3506 C CA  . GLU B 2 118 ? 158.230 120.609 171.904 1.00 95.39  ? 118 GLU B CA  1 
ATOM   3507 C C   . GLU B 2 118 ? 157.625 120.556 173.301 1.00 95.39  ? 118 GLU B C   1 
ATOM   3508 O O   . GLU B 2 118 ? 156.561 119.950 173.460 1.00 95.39  ? 118 GLU B O   1 
ATOM   3509 C CB  . GLU B 2 118 ? 158.894 119.260 171.582 1.00 95.39  ? 118 GLU B CB  1 
ATOM   3510 C CG  . GLU B 2 118 ? 157.957 118.075 171.595 1.00 95.39  ? 118 GLU B CG  1 
ATOM   3511 C CD  . GLU B 2 118 ? 156.890 118.180 170.521 1.00 95.39  ? 118 GLU B CD  1 
ATOM   3512 O OE1 . GLU B 2 118 ? 157.131 118.866 169.504 1.00 95.39  ? 118 GLU B OE1 1 
ATOM   3513 O OE2 . GLU B 2 118 ? 155.811 117.576 170.691 1.00 95.39  ? 118 GLU B OE2 1 
ATOM   3514 N N   . ASP B 2 119 ? 158.228 121.179 174.311 1.00 94.38  ? 119 ASP B N   1 
ATOM   3515 C CA  . ASP B 2 119 ? 157.709 121.095 175.680 1.00 94.38  ? 119 ASP B CA  1 
ATOM   3516 C C   . ASP B 2 119 ? 157.321 122.495 176.169 1.00 94.38  ? 119 ASP B C   1 
ATOM   3517 O O   . ASP B 2 119 ? 158.021 123.158 176.934 1.00 94.38  ? 119 ASP B O   1 
ATOM   3518 C CB  . ASP B 2 119 ? 158.719 120.343 176.607 1.00 94.38  ? 119 ASP B CB  1 
ATOM   3519 C CG  . ASP B 2 119 ? 159.963 121.153 176.950 1.00 94.38  ? 119 ASP B CG  1 
ATOM   3520 O OD1 . ASP B 2 119 ? 160.721 120.714 177.839 1.00 94.38  ? 119 ASP B OD1 1 
ATOM   3521 O OD2 . ASP B 2 119 ? 160.234 122.172 176.288 1.00 94.38  ? 119 ASP B OD2 1 
ATOM   3522 N N   . LYS B 2 120 ? 156.126 122.919 175.763 1.00 84.15  ? 120 LYS B N   1 
ATOM   3523 C CA  . LYS B 2 120 ? 155.743 124.313 175.923 1.00 84.15  ? 120 LYS B CA  1 
ATOM   3524 C C   . LYS B 2 120 ? 155.597 124.701 177.385 1.00 84.15  ? 120 LYS B C   1 
ATOM   3525 O O   . LYS B 2 120 ? 155.914 125.834 177.761 1.00 84.15  ? 120 LYS B O   1 
ATOM   3526 C CB  . LYS B 2 120 ? 154.447 124.568 175.163 1.00 84.15  ? 120 LYS B CB  1 
ATOM   3527 C CG  . LYS B 2 120 ? 154.495 124.088 173.723 1.00 84.15  ? 120 LYS B CG  1 
ATOM   3528 C CD  . LYS B 2 120 ? 155.590 124.790 172.949 1.00 84.15  ? 120 LYS B CD  1 
ATOM   3529 C CE  . LYS B 2 120 ? 155.516 124.470 171.475 1.00 84.15  ? 120 LYS B CE  1 
ATOM   3530 N NZ  . LYS B 2 120 ? 155.836 123.053 171.220 1.00 84.15  ? 120 LYS B NZ  1 
ATOM   3531 N N   . GLY B 2 121 ? 155.143 123.786 178.224 1.00 84.00  ? 121 GLY B N   1 
ATOM   3532 C CA  . GLY B 2 121 ? 154.973 124.075 179.627 1.00 84.00  ? 121 GLY B CA  1 
ATOM   3533 C C   . GLY B 2 121 ? 153.545 124.424 179.986 1.00 84.00  ? 121 GLY B C   1 
ATOM   3534 O O   . GLY B 2 121 ? 152.596 124.193 179.234 1.00 84.00  ? 121 GLY B O   1 
ATOM   3535 N N   . GLU B 2 122 ? 153.399 124.993 181.173 1.00 81.69  ? 122 GLU B N   1 
ATOM   3536 C CA  . GLU B 2 122 ? 152.079 125.272 181.703 1.00 81.69  ? 122 GLU B CA  1 
ATOM   3537 C C   . GLU B 2 122 ? 151.486 126.492 180.995 1.00 81.69  ? 122 GLU B C   1 
ATOM   3538 O O   . GLU B 2 122 ? 152.117 127.548 180.938 1.00 81.69  ? 122 GLU B O   1 
ATOM   3539 C CB  . GLU B 2 122 ? 152.177 125.512 183.208 1.00 81.69  ? 122 GLU B CB  1 
ATOM   3540 C CG  . GLU B 2 122 ? 150.869 125.762 183.921 1.00 81.69  ? 122 GLU B CG  1 
ATOM   3541 C CD  . GLU B 2 122 ? 149.957 124.553 183.895 1.00 81.69  ? 122 GLU B CD  1 
ATOM   3542 O OE1 . GLU B 2 122 ? 150.475 123.423 183.782 1.00 81.69  ? 122 GLU B OE1 1 
ATOM   3543 O OE2 . GLU B 2 122 ? 148.722 124.731 183.980 1.00 81.69  ? 122 GLU B OE2 1 
ATOM   3544 N N   . PRO B 2 123 ? 150.278 126.377 180.447 1.00 74.88  ? 123 PRO B N   1 
ATOM   3545 C CA  . PRO B 2 123 ? 149.727 127.460 179.629 1.00 74.88  ? 123 PRO B CA  1 
ATOM   3546 C C   . PRO B 2 123 ? 149.332 128.693 180.424 1.00 74.88  ? 123 PRO B C   1 
ATOM   3547 O O   . PRO B 2 123 ? 149.009 128.637 181.611 1.00 74.88  ? 123 PRO B O   1 
ATOM   3548 C CB  . PRO B 2 123 ? 148.493 126.821 178.978 1.00 74.88  ? 123 PRO B CB  1 
ATOM   3549 C CG  . PRO B 2 123 ? 148.205 125.596 179.738 1.00 74.88  ? 123 PRO B CG  1 
ATOM   3550 C CD  . PRO B 2 123 ? 149.272 125.348 180.744 1.00 74.88  ? 123 PRO B CD  1 
ATOM   3551 N N   . GLY B 2 124 ? 149.368 129.830 179.728 1.00 70.19  ? 124 GLY B N   1 
ATOM   3552 C CA  . GLY B 2 124 ? 149.105 131.102 180.379 1.00 70.19  ? 124 GLY B CA  1 
ATOM   3553 C C   . GLY B 2 124 ? 147.667 131.253 180.827 1.00 70.19  ? 124 GLY B C   1 
ATOM   3554 O O   . GLY B 2 124 ? 147.398 131.743 181.923 1.00 70.19  ? 124 GLY B O   1 
ATOM   3555 N N   . TYR B 2 125 ? 146.722 130.844 179.981 1.00 65.34  ? 125 TYR B N   1 
ATOM   3556 C CA  . TYR B 2 125 ? 145.300 130.945 180.281 1.00 65.34  ? 125 TYR B CA  1 
ATOM   3557 C C   . TYR B 2 125 ? 144.649 129.582 180.134 1.00 65.34  ? 125 TYR B C   1 
ATOM   3558 O O   . TYR B 2 125 ? 144.934 128.857 179.180 1.00 65.34  ? 125 TYR B O   1 
ATOM   3559 C CB  . TYR B 2 125 ? 144.605 131.938 179.362 1.00 65.34  ? 125 TYR B CB  1 
ATOM   3560 C CG  . TYR B 2 125 ? 144.772 133.361 179.788 1.00 65.34  ? 125 TYR B CG  1 
ATOM   3561 C CD1 . TYR B 2 125 ? 144.292 133.796 180.998 1.00 65.34  ? 125 TYR B CD1 1 
ATOM   3562 C CD2 . TYR B 2 125 ? 145.405 134.271 178.974 1.00 65.34  ? 125 TYR B CD2 1 
ATOM   3563 C CE1 . TYR B 2 125 ? 144.445 135.089 181.385 1.00 65.34  ? 125 TYR B CE1 1 
ATOM   3564 C CE2 . TYR B 2 125 ? 145.559 135.566 179.356 1.00 65.34  ? 125 TYR B CE2 1 
ATOM   3565 C CZ  . TYR B 2 125 ? 145.080 135.969 180.563 1.00 65.34  ? 125 TYR B CZ  1 
ATOM   3566 O OH  . TYR B 2 125 ? 145.232 137.270 180.954 1.00 65.34  ? 125 TYR B OH  1 
ATOM   3567 N N   . VAL B 2 126 ? 143.773 129.245 181.073 1.00 68.07  ? 126 VAL B N   1 
ATOM   3568 C CA  . VAL B 2 126 ? 143.017 128.000 181.061 1.00 68.07  ? 126 VAL B CA  1 
ATOM   3569 C C   . VAL B 2 126 ? 141.572 128.330 181.392 1.00 68.07  ? 126 VAL B C   1 
ATOM   3570 O O   . VAL B 2 126 ? 141.310 129.086 182.332 1.00 68.07  ? 126 VAL B O   1 
ATOM   3571 C CB  . VAL B 2 126 ? 143.586 126.987 182.068 1.00 68.07  ? 126 VAL B CB  1 
ATOM   3572 C CG1 . VAL B 2 126 ? 142.590 125.898 182.340 1.00 68.07  ? 126 VAL B CG1 1 
ATOM   3573 C CG2 . VAL B 2 126 ? 144.868 126.396 181.541 1.00 68.07  ? 126 VAL B CG2 1 
ATOM   3574 N N   . ALA B 2 127 ? 140.637 127.776 180.626 1.00 66.53  ? 127 ALA B N   1 
ATOM   3575 C CA  . ALA B 2 127 ? 139.227 128.091 180.786 1.00 66.53  ? 127 ALA B CA  1 
ATOM   3576 C C   . ALA B 2 127 ? 138.391 126.829 180.902 1.00 66.53  ? 127 ALA B C   1 
ATOM   3577 O O   . ALA B 2 127 ? 138.692 125.815 180.271 1.00 66.53  ? 127 ALA B O   1 
ATOM   3578 C CB  . ALA B 2 127 ? 138.714 128.913 179.622 1.00 66.53  ? 127 ALA B CB  1 
ATOM   3579 N N   . TYR B 2 128 ? 137.332 126.912 181.699 1.00 72.49  ? 128 TYR B N   1 
ATOM   3580 C CA  . TYR B 2 128 ? 136.352 125.844 181.880 1.00 72.49  ? 128 TYR B CA  1 
ATOM   3581 C C   . TYR B 2 128 ? 135.030 126.362 181.341 1.00 72.49  ? 128 TYR B C   1 
ATOM   3582 O O   . TYR B 2 128 ? 134.582 127.440 181.732 1.00 72.49  ? 128 TYR B O   1 
ATOM   3583 C CB  . TYR B 2 128 ? 136.206 125.475 183.346 1.00 72.49  ? 128 TYR B CB  1 
ATOM   3584 C CG  . TYR B 2 128 ? 137.290 124.606 183.894 1.00 72.49  ? 128 TYR B CG  1 
ATOM   3585 C CD1 . TYR B 2 128 ? 137.395 123.286 183.521 1.00 72.49  ? 128 TYR B CD1 1 
ATOM   3586 C CD2 . TYR B 2 128 ? 138.202 125.105 184.800 1.00 72.49  ? 128 TYR B CD2 1 
ATOM   3587 C CE1 . TYR B 2 128 ? 138.379 122.491 184.030 1.00 72.49  ? 128 TYR B CE1 1 
ATOM   3588 C CE2 . TYR B 2 128 ? 139.192 124.319 185.311 1.00 72.49  ? 128 TYR B CE2 1 
ATOM   3589 C CZ  . TYR B 2 128 ? 139.277 123.013 184.925 1.00 72.49  ? 128 TYR B CZ  1 
ATOM   3590 O OH  . TYR B 2 128 ? 140.273 122.222 185.438 1.00 72.49  ? 128 TYR B OH  1 
ATOM   3591 N N   . VAL B 2 129 ? 134.395 125.600 180.465 1.00 67.02  ? 129 VAL B N   1 
ATOM   3592 C CA  . VAL B 2 129 ? 133.140 125.999 179.880 1.00 67.02  ? 129 VAL B CA  1 
ATOM   3593 C C   . VAL B 2 129 ? 132.139 124.861 180.031 1.00 67.02  ? 129 VAL B C   1 
ATOM   3594 O O   . VAL B 2 129 ? 132.505 123.706 180.213 1.00 67.02  ? 129 VAL B O   1 
ATOM   3595 C CB  . VAL B 2 129 ? 133.318 126.415 178.409 1.00 67.02  ? 129 VAL B CB  1 
ATOM   3596 C CG1 . VAL B 2 129 ? 133.536 125.214 177.563 1.00 67.02  ? 129 VAL B CG1 1 
ATOM   3597 C CG2 . VAL B 2 129 ? 132.116 127.180 177.924 1.00 67.02  ? 129 VAL B CG2 1 
ATOM   3598 N N   . GLY B 2 130 ? 130.852 125.188 179.977 1.00 69.91  ? 130 GLY B N   1 
ATOM   3599 C CA  . GLY B 2 130 ? 129.819 124.173 180.049 1.00 69.91  ? 130 GLY B CA  1 
ATOM   3600 C C   . GLY B 2 130 ? 128.439 124.693 179.714 1.00 69.91  ? 130 GLY B C   1 
ATOM   3601 O O   . GLY B 2 130 ? 128.310 125.653 178.963 1.00 69.91  ? 130 GLY B O   1 
ATOM   3602 N N   . TYR B 2 131 ? 127.402 124.062 180.259 1.00 71.39  ? 131 TYR B N   1 
ATOM   3603 C CA  . TYR B 2 131 ? 126.032 124.559 180.165 1.00 71.39  ? 131 TYR B CA  1 
ATOM   3604 C C   . TYR B 2 131 ? 125.454 124.697 181.571 1.00 71.39  ? 131 TYR B C   1 
ATOM   3605 O O   . TYR B 2 131 ? 126.176 124.539 182.558 1.00 71.39  ? 131 TYR B O   1 
ATOM   3606 C CB  . TYR B 2 131 ? 125.196 123.641 179.252 1.00 71.39  ? 131 TYR B CB  1 
ATOM   3607 C CG  . TYR B 2 131 ? 125.370 123.810 177.771 1.00 71.39  ? 131 TYR B CG  1 
ATOM   3608 C CD1 . TYR B 2 131 ? 125.900 124.957 177.244 1.00 71.39  ? 131 TYR B CD1 1 
ATOM   3609 C CD2 . TYR B 2 131 ? 125.001 122.811 176.900 1.00 71.39  ? 131 TYR B CD2 1 
ATOM   3610 C CE1 . TYR B 2 131 ? 126.021 125.117 175.890 1.00 71.39  ? 131 TYR B CE1 1 
ATOM   3611 C CE2 . TYR B 2 131 ? 125.138 122.960 175.552 1.00 71.39  ? 131 TYR B CE2 1 
ATOM   3612 C CZ  . TYR B 2 131 ? 125.651 124.113 175.054 1.00 71.39  ? 131 TYR B CZ  1 
ATOM   3613 O OH  . TYR B 2 131 ? 125.788 124.255 173.701 1.00 71.39  ? 131 TYR B OH  1 
ATOM   3614 N N   . ASP B 2 132 ? 124.162 124.994 181.656 1.00 80.95  ? 132 ASP B N   1 
ATOM   3615 C CA  . ASP B 2 132 ? 123.490 125.162 182.930 1.00 80.95  ? 132 ASP B CA  1 
ATOM   3616 C C   . ASP B 2 132 ? 122.875 123.876 183.451 1.00 80.95  ? 132 ASP B C   1 
ATOM   3617 O O   . ASP B 2 132 ? 122.552 123.800 184.641 1.00 80.95  ? 132 ASP B O   1 
ATOM   3618 C CB  . ASP B 2 132 ? 122.410 126.244 182.821 1.00 80.95  ? 132 ASP B CB  1 
ATOM   3619 C CG  . ASP B 2 132 ? 122.983 127.635 182.911 1.00 80.95  ? 132 ASP B CG  1 
ATOM   3620 O OD1 . ASP B 2 132 ? 122.255 128.608 182.630 1.00 80.95  ? 132 ASP B OD1 1 
ATOM   3621 O OD2 . ASP B 2 132 ? 124.169 127.752 183.271 1.00 80.95  ? 132 ASP B OD2 1 
ATOM   3622 N N   . THR B 2 133 ? 122.704 122.864 182.605 1.00 84.65  ? 133 THR B N   1 
ATOM   3623 C CA  . THR B 2 133 ? 122.321 121.546 183.086 1.00 84.65  ? 133 THR B CA  1 
ATOM   3624 C C   . THR B 2 133 ? 123.397 120.922 183.953 1.00 84.65  ? 133 THR B C   1 
ATOM   3625 O O   . THR B 2 133 ? 123.114 119.977 184.695 1.00 84.65  ? 133 THR B O   1 
ATOM   3626 C CB  . THR B 2 133 ? 122.020 120.616 181.912 1.00 84.65  ? 133 THR B CB  1 
ATOM   3627 O OG1 . THR B 2 133 ? 123.247 120.224 181.290 1.00 84.65  ? 133 THR B OG1 1 
ATOM   3628 C CG2 . THR B 2 133 ? 121.157 121.318 180.894 1.00 84.65  ? 133 THR B CG2 1 
ATOM   3629 N N   . ASP B 2 134 ? 124.620 121.430 183.867 1.00 82.58  ? 134 ASP B N   1 
ATOM   3630 C CA  . ASP B 2 134 ? 125.760 120.992 184.654 1.00 82.58  ? 134 ASP B CA  1 
ATOM   3631 C C   . ASP B 2 134 ? 126.575 122.192 185.109 1.00 82.58  ? 134 ASP B C   1 
ATOM   3632 O O   . ASP B 2 134 ? 127.805 122.201 185.046 1.00 82.58  ? 134 ASP B O   1 
ATOM   3633 C CB  . ASP B 2 134 ? 126.589 119.987 183.860 1.00 82.58  ? 134 ASP B CB  1 
ATOM   3634 C CG  . ASP B 2 134 ? 127.166 120.575 182.594 1.00 82.58  ? 134 ASP B CG  1 
ATOM   3635 O OD1 . ASP B 2 134 ? 126.894 121.756 182.303 1.00 82.58  ? 134 ASP B OD1 1 
ATOM   3636 O OD2 . ASP B 2 134 ? 127.865 119.843 181.864 1.00 82.58  ? 134 ASP B OD2 1 
ATOM   3637 N N   . SER B 2 135 ? 125.878 123.230 185.575 1.00 83.71  ? 135 SER B N   1 
ATOM   3638 C CA  . SER B 2 135 ? 126.541 124.450 186.018 1.00 83.71  ? 135 SER B CA  1 
ATOM   3639 C C   . SER B 2 135 ? 127.291 124.252 187.323 1.00 83.71  ? 135 SER B C   1 
ATOM   3640 O O   . SER B 2 135 ? 128.347 124.858 187.529 1.00 83.71  ? 135 SER B O   1 
ATOM   3641 C CB  . SER B 2 135 ? 125.517 125.566 186.184 1.00 83.71  ? 135 SER B CB  1 
ATOM   3642 O OG  . SER B 2 135 ? 126.111 126.696 186.795 1.00 83.71  ? 135 SER B OG  1 
ATOM   3643 N N   . GLU B 2 136 ? 126.735 123.418 188.197 1.00 89.52  ? 136 GLU B N   1 
ATOM   3644 C CA  . GLU B 2 136 ? 127.347 123.132 189.487 1.00 89.52  ? 136 GLU B CA  1 
ATOM   3645 C C   . GLU B 2 136 ? 128.769 122.627 189.294 1.00 89.52  ? 136 GLU B C   1 
ATOM   3646 O O   . GLU B 2 136 ? 129.681 123.017 190.024 1.00 89.52  ? 136 GLU B O   1 
ATOM   3647 C CB  . GLU B 2 136 ? 126.522 122.100 190.257 1.00 89.52  ? 136 GLU B CB  1 
ATOM   3648 C CG  . GLU B 2 136 ? 125.861 122.645 191.513 1.00 89.52  ? 136 GLU B CG  1 
ATOM   3649 C CD  . GLU B 2 136 ? 126.837 122.814 192.659 1.00 89.52  ? 136 GLU B CD  1 
ATOM   3650 O OE1 . GLU B 2 136 ? 127.757 123.651 192.540 1.00 89.52  ? 136 GLU B OE1 1 
ATOM   3651 O OE2 . GLU B 2 136 ? 126.685 122.111 193.680 1.00 89.52  ? 136 GLU B OE2 1 
ATOM   3652 N N   . LEU B 2 137 ? 128.955 121.758 188.306 1.00 84.67  ? 137 LEU B N   1 
ATOM   3653 C CA  . LEU B 2 137 ? 130.276 121.216 188.023 1.00 84.67  ? 137 LEU B CA  1 
ATOM   3654 C C   . LEU B 2 137 ? 131.253 122.318 187.639 1.00 84.67  ? 137 LEU B C   1 
ATOM   3655 O O   . LEU B 2 137 ? 132.390 122.344 188.122 1.00 84.67  ? 137 LEU B O   1 
ATOM   3656 C CB  . LEU B 2 137 ? 130.192 120.170 186.918 1.00 84.67  ? 137 LEU B CB  1 
ATOM   3657 C CG  . LEU B 2 137 ? 131.538 119.593 186.496 1.00 84.67  ? 137 LEU B CG  1 
ATOM   3658 C CD1 . LEU B 2 137 ? 132.233 118.943 187.671 1.00 84.67  ? 137 LEU B CD1 1 
ATOM   3659 C CD2 . LEU B 2 137 ? 131.344 118.602 185.384 1.00 84.67  ? 137 LEU B CD2 1 
ATOM   3660 N N   . VAL B 2 138 ? 130.830 123.240 186.770 1.00 78.80  ? 138 VAL B N   1 
ATOM   3661 C CA  . VAL B 2 138 ? 131.712 124.333 186.376 1.00 78.80  ? 138 VAL B CA  1 
ATOM   3662 C C   . VAL B 2 138 ? 132.054 125.188 187.582 1.00 78.80  ? 138 VAL B C   1 
ATOM   3663 O O   . VAL B 2 138 ? 133.192 125.637 187.741 1.00 78.80  ? 138 VAL B O   1 
ATOM   3664 C CB  . VAL B 2 138 ? 131.077 125.173 185.256 1.00 78.80  ? 138 VAL B CB  1 
ATOM   3665 C CG1 . VAL B 2 138 ? 131.985 126.306 184.889 1.00 78.80  ? 138 VAL B CG1 1 
ATOM   3666 C CG2 . VAL B 2 138 ? 130.808 124.326 184.052 1.00 78.80  ? 138 VAL B CG2 1 
ATOM   3667 N N   . GLN B 2 139 ? 131.074 125.424 188.455 1.00 86.28  ? 139 GLN B N   1 
ATOM   3668 C CA  . GLN B 2 139 ? 131.351 126.139 189.696 1.00 86.28  ? 139 GLN B CA  1 
ATOM   3669 C C   . GLN B 2 139 ? 132.381 125.404 190.541 1.00 86.28  ? 139 GLN B C   1 
ATOM   3670 O O   . GLN B 2 139 ? 133.194 126.031 191.228 1.00 86.28  ? 139 GLN B O   1 
ATOM   3671 C CB  . GLN B 2 139 ? 130.060 126.334 190.485 1.00 86.28  ? 139 GLN B CB  1 
ATOM   3672 C CG  . GLN B 2 139 ? 130.233 127.124 191.768 1.00 86.28  ? 139 GLN B CG  1 
ATOM   3673 C CD  . GLN B 2 139 ? 130.720 128.533 191.534 1.00 86.28  ? 139 GLN B CD  1 
ATOM   3674 O OE1 . GLN B 2 139 ? 131.887 128.844 191.768 1.00 86.28  ? 139 GLN B OE1 1 
ATOM   3675 N NE2 . GLN B 2 139 ? 129.823 129.404 191.087 1.00 86.28  ? 139 GLN B NE2 1 
ATOM   3676 N N   . GLU B 2 140 ? 132.354 124.071 190.512 1.00 87.94  ? 140 GLU B N   1 
ATOM   3677 C CA  . GLU B 2 140 ? 133.328 123.297 191.274 1.00 87.94  ? 140 GLU B CA  1 
ATOM   3678 C C   . GLU B 2 140 ? 134.728 123.404 190.686 1.00 87.94  ? 140 GLU B C   1 
ATOM   3679 O O   . GLU B 2 140 ? 135.695 123.607 191.426 1.00 87.94  ? 140 GLU B O   1 
ATOM   3680 C CB  . GLU B 2 140 ? 132.902 121.834 191.345 1.00 87.94  ? 140 GLU B CB  1 
ATOM   3681 C CG  . GLU B 2 140 ? 131.634 121.605 192.132 1.00 87.94  ? 140 GLU B CG  1 
ATOM   3682 C CD  . GLU B 2 140 ? 131.805 121.915 193.600 1.00 87.94  ? 140 GLU B CD  1 
ATOM   3683 O OE1 . GLU B 2 140 ? 132.923 121.724 194.119 1.00 87.94  ? 140 GLU B OE1 1 
ATOM   3684 O OE2 . GLU B 2 140 ? 130.823 122.350 194.235 1.00 87.94  ? 140 GLU B OE2 1 
ATOM   3685 N N   . LEU B 2 141 ? 134.863 123.257 189.367 1.00 83.13  ? 141 LEU B N   1 
ATOM   3686 C CA  . LEU B 2 141 ? 136.188 123.353 188.762 1.00 83.13  ? 141 LEU B CA  1 
ATOM   3687 C C   . LEU B 2 141 ? 136.760 124.758 188.872 1.00 83.13  ? 141 LEU B C   1 
ATOM   3688 O O   . LEU B 2 141 ? 137.900 124.927 189.315 1.00 83.13  ? 141 LEU B O   1 
ATOM   3689 C CB  . LEU B 2 141 ? 136.139 122.920 187.303 1.00 83.13  ? 141 LEU B CB  1 
ATOM   3690 C CG  . LEU B 2 141 ? 135.343 121.649 187.050 1.00 83.13  ? 141 LEU B CG  1 
ATOM   3691 C CD1 . LEU B 2 141 ? 135.003 121.527 185.588 1.00 83.13  ? 141 LEU B CD1 1 
ATOM   3692 C CD2 . LEU B 2 141 ? 136.139 120.452 187.514 1.00 83.13  ? 141 LEU B CD2 1 
ATOM   3693 N N   . CYS B 2 142 ? 135.994 125.770 188.487 1.00 85.37  ? 142 CYS B N   1 
ATOM   3694 C CA  . CYS B 2 142 ? 136.406 127.154 188.683 1.00 85.37  ? 142 CYS B CA  1 
ATOM   3695 C C   . CYS B 2 142 ? 136.241 127.449 190.163 1.00 85.37  ? 142 CYS B C   1 
ATOM   3696 O O   . CYS B 2 142 ? 135.211 127.956 190.605 1.00 85.37  ? 142 CYS B O   1 
ATOM   3697 C CB  . CYS B 2 142 ? 135.571 128.094 187.830 1.00 85.37  ? 142 CYS B CB  1 
ATOM   3698 S SG  . CYS B 2 142 ? 135.392 127.578 186.125 1.00 85.37  ? 142 CYS B SG  1 
ATOM   3699 N N   . ALA B 2 143 ? 137.268 127.107 190.941 1.00 89.81  ? 143 ALA B N   1 
ATOM   3700 C CA  . ALA B 2 143 ? 137.153 127.148 192.394 1.00 89.81  ? 143 ALA B CA  1 
ATOM   3701 C C   . ALA B 2 143 ? 136.807 128.544 192.887 1.00 89.81  ? 143 ALA B C   1 
ATOM   3702 O O   . ALA B 2 143 ? 135.834 128.739 193.621 1.00 89.81  ? 143 ALA B O   1 
ATOM   3703 C CB  . ALA B 2 143 ? 138.456 126.661 193.030 1.00 89.81  ? 143 ALA B CB  1 
ATOM   3704 N N   . ASP B 2 144 ? 137.591 129.531 192.483 1.00 90.60  ? 144 ASP B N   1 
ATOM   3705 C CA  . ASP B 2 144 ? 137.371 130.889 192.943 1.00 90.60  ? 144 ASP B CA  1 
ATOM   3706 C C   . ASP B 2 144 ? 137.211 131.862 191.787 1.00 90.60  ? 144 ASP B C   1 
ATOM   3707 O O   . ASP B 2 144 ? 136.574 132.904 191.967 1.00 90.60  ? 144 ASP B O   1 
ATOM   3708 C CB  . ASP B 2 144 ? 138.533 131.310 193.869 1.00 90.60  ? 144 ASP B CB  1 
ATOM   3709 C CG  . ASP B 2 144 ? 138.385 132.717 194.433 1.00 90.60  ? 144 ASP B CG  1 
ATOM   3710 O OD1 . ASP B 2 144 ? 138.291 133.699 193.671 1.00 90.60  ? 144 ASP B OD1 1 
ATOM   3711 O OD2 . ASP B 2 144 ? 138.350 132.839 195.674 1.00 90.60  ? 144 ASP B OD2 1 
ATOM   3712 N N   . SER B 2 145 ? 137.702 131.527 190.600 1.00 83.65  ? 145 SER B N   1 
ATOM   3713 C CA  . SER B 2 145 ? 137.597 132.415 189.457 1.00 83.65  ? 145 SER B CA  1 
ATOM   3714 C C   . SER B 2 145 ? 136.143 132.774 189.183 1.00 83.65  ? 145 SER B C   1 
ATOM   3715 O O   . SER B 2 145 ? 135.244 131.939 189.285 1.00 83.65  ? 145 SER B O   1 
ATOM   3716 C CB  . SER B 2 145 ? 138.208 131.758 188.227 1.00 83.65  ? 145 SER B CB  1 
ATOM   3717 O OG  . SER B 2 145 ? 139.593 131.547 188.410 1.00 83.65  ? 145 SER B OG  1 
ATOM   3718 N N   . THR B 2 146 ? 135.920 134.040 188.847 1.00 80.63  ? 146 THR B N   1 
ATOM   3719 C CA  . THR B 2 146 ? 134.570 134.513 188.591 1.00 80.63  ? 146 THR B CA  1 
ATOM   3720 C C   . THR B 2 146 ? 133.961 133.764 187.416 1.00 80.63  ? 146 THR B C   1 
ATOM   3721 O O   . THR B 2 146 ? 134.615 133.543 186.396 1.00 80.63  ? 146 THR B O   1 
ATOM   3722 C CB  . THR B 2 146 ? 134.583 136.010 188.306 1.00 80.63  ? 146 THR B CB  1 
ATOM   3723 O OG1 . THR B 2 146 ? 135.085 136.706 189.451 1.00 80.63  ? 146 THR B OG1 1 
ATOM   3724 C CG2 . THR B 2 146 ? 133.182 136.499 188.008 1.00 80.63  ? 146 THR B CG2 1 
ATOM   3725 N N   . ILE B 2 147 ? 132.703 133.363 187.570 1.00 74.91  ? 147 ILE B N   1 
ATOM   3726 C CA  . ILE B 2 147 ? 131.958 132.655 186.539 1.00 74.91  ? 147 ILE B CA  1 
ATOM   3727 C C   . ILE B 2 147 ? 131.257 133.681 185.669 1.00 74.91  ? 147 ILE B C   1 
ATOM   3728 O O   . ILE B 2 147 ? 130.599 134.592 186.183 1.00 74.91  ? 147 ILE B O   1 
ATOM   3729 C CB  . ILE B 2 147 ? 130.936 131.683 187.145 1.00 74.91  ? 147 ILE B CB  1 
ATOM   3730 C CG1 . ILE B 2 147 ? 131.632 130.672 188.035 1.00 74.91  ? 147 ILE B CG1 1 
ATOM   3731 C CG2 . ILE B 2 147 ? 130.224 130.945 186.049 1.00 74.91  ? 147 ILE B CG2 1 
ATOM   3732 C CD1 . ILE B 2 147 ? 132.472 129.716 187.269 1.00 74.91  ? 147 ILE B CD1 1 
ATOM   3733 N N   . TYR B 2 148 ? 131.397 133.540 184.360 1.00 71.05  ? 148 TYR B N   1 
ATOM   3734 C CA  . TYR B 2 148 ? 130.723 134.401 183.405 1.00 71.05  ? 148 TYR B CA  1 
ATOM   3735 C C   . TYR B 2 148 ? 129.575 133.632 182.777 1.00 71.05  ? 148 TYR B C   1 
ATOM   3736 O O   . TYR B 2 148 ? 129.688 132.426 182.552 1.00 71.05  ? 148 TYR B O   1 
ATOM   3737 C CB  . TYR B 2 148 ? 131.691 134.871 182.326 1.00 71.05  ? 148 TYR B CB  1 
ATOM   3738 C CG  . TYR B 2 148 ? 132.780 135.753 182.850 1.00 71.05  ? 148 TYR B CG  1 
ATOM   3739 C CD1 . TYR B 2 148 ? 132.508 137.029 183.287 1.00 71.05  ? 148 TYR B CD1 1 
ATOM   3740 C CD2 . TYR B 2 148 ? 134.078 135.299 182.932 1.00 71.05  ? 148 TYR B CD2 1 
ATOM   3741 C CE1 . TYR B 2 148 ? 133.497 137.832 183.773 1.00 71.05  ? 148 TYR B CE1 1 
ATOM   3742 C CE2 . TYR B 2 148 ? 135.073 136.094 183.420 1.00 71.05  ? 148 TYR B CE2 1 
ATOM   3743 C CZ  . TYR B 2 148 ? 134.778 137.358 183.838 1.00 71.05  ? 148 TYR B CZ  1 
ATOM   3744 O OH  . TYR B 2 148 ? 135.777 138.154 184.327 1.00 71.05  ? 148 TYR B OH  1 
ATOM   3745 N N   . HIS B 2 149 ? 128.476 134.323 182.503 1.00 67.25  ? 149 HIS B N   1 
ATOM   3746 C CA  . HIS B 2 149 ? 127.323 133.716 181.859 1.00 67.25  ? 149 HIS B CA  1 
ATOM   3747 C C   . HIS B 2 149 ? 127.125 134.312 180.477 1.00 67.25  ? 149 HIS B C   1 
ATOM   3748 O O   . HIS B 2 149 ? 127.617 135.401 180.183 1.00 67.25  ? 149 HIS B O   1 
ATOM   3749 C CB  . HIS B 2 149 ? 126.064 133.905 182.695 1.00 67.25  ? 149 HIS B CB  1 
ATOM   3750 C CG  . HIS B 2 149 ? 126.217 133.463 184.113 1.00 67.25  ? 149 HIS B CG  1 
ATOM   3751 N ND1 . HIS B 2 149 ? 126.065 132.152 184.503 1.00 67.25  ? 149 HIS B ND1 1 
ATOM   3752 C CD2 . HIS B 2 149 ? 126.514 134.157 185.235 1.00 67.25  ? 149 HIS B CD2 1 
ATOM   3753 C CE1 . HIS B 2 149 ? 126.262 132.056 185.805 1.00 67.25  ? 149 HIS B CE1 1 
ATOM   3754 N NE2 . HIS B 2 149 ? 126.535 133.259 186.273 1.00 67.25  ? 149 HIS B NE2 1 
ATOM   3755 N N   . MET B 2 150 ? 126.417 133.584 179.629 1.00 65.79  ? 150 MET B N   1 
ATOM   3756 C CA  . MET B 2 150 ? 126.190 134.012 178.263 1.00 65.79  ? 150 MET B CA  1 
ATOM   3757 C C   . MET B 2 150 ? 124.801 133.614 177.797 1.00 65.79  ? 150 MET B C   1 
ATOM   3758 O O   . MET B 2 150 ? 123.987 133.122 178.573 1.00 65.79  ? 150 MET B O   1 
ATOM   3759 C CB  . MET B 2 150 ? 127.231 133.407 177.336 1.00 65.79  ? 150 MET B CB  1 
ATOM   3760 C CG  . MET B 2 150 ? 128.597 134.014 177.438 1.00 65.79  ? 150 MET B CG  1 
ATOM   3761 S SD  . MET B 2 150 ? 129.396 133.991 175.837 1.00 65.79  ? 150 MET B SD  1 
ATOM   3762 C CE  . MET B 2 150 ? 130.796 135.036 176.170 1.00 65.79  ? 150 MET B CE  1 
ATOM   3763 O OXT . MET B 2 150 ? 124.460 133.777 176.628 1.00 65.79  ? 150 MET B OXT 1 
ATOM   3764 N N   . ILE C 1 71  ? 130.975 97.060  121.847 1.00 161.32 ? 71  ILE C N   1 
ATOM   3765 C CA  . ILE C 1 71  ? 131.982 97.580  120.934 1.00 161.32 ? 71  ILE C CA  1 
ATOM   3766 C C   . ILE C 1 71  ? 132.005 99.101  121.024 1.00 161.32 ? 71  ILE C C   1 
ATOM   3767 O O   . ILE C 1 71  ? 130.986 99.754  120.824 1.00 161.32 ? 71  ILE C O   1 
ATOM   3768 C CB  . ILE C 1 71  ? 131.732 97.116  119.495 1.00 161.32 ? 71  ILE C CB  1 
ATOM   3769 C CG1 . ILE C 1 71  ? 131.807 95.590  119.405 1.00 161.32 ? 71  ILE C CG1 1 
ATOM   3770 C CG2 . ILE C 1 71  ? 132.749 97.747  118.556 1.00 161.32 ? 71  ILE C CG2 1 
ATOM   3771 C CD1 . ILE C 1 71  ? 130.467 94.892  119.553 1.00 161.32 ? 71  ILE C CD1 1 
ATOM   3772 N N   . TRP C 1 72  ? 133.192 99.640  121.292 1.00 162.25 ? 72  TRP C N   1 
ATOM   3773 C CA  . TRP C 1 72  ? 133.433 101.029 121.713 1.00 162.25 ? 72  TRP C CA  1 
ATOM   3774 C C   . TRP C 1 72  ? 132.620 102.028 120.880 1.00 162.25 ? 72  TRP C C   1 
ATOM   3775 O O   . TRP C 1 72  ? 131.656 102.612 121.398 1.00 162.25 ? 72  TRP C O   1 
ATOM   3776 C CB  . TRP C 1 72  ? 134.949 101.192 121.691 1.00 162.25 ? 72  TRP C CB  1 
ATOM   3777 C CG  . TRP C 1 72  ? 135.575 100.940 120.337 1.00 162.25 ? 72  TRP C CG  1 
ATOM   3778 C CD1 . TRP C 1 72  ? 135.768 101.838 119.335 1.00 162.25 ? 72  TRP C CD1 1 
ATOM   3779 C CD2 . TRP C 1 72  ? 136.066 99.686  119.844 1.00 162.25 ? 72  TRP C CD2 1 
ATOM   3780 N NE1 . TRP C 1 72  ? 136.354 101.231 118.251 1.00 162.25 ? 72  TRP C NE1 1 
ATOM   3781 C CE2 . TRP C 1 72  ? 136.549 99.907  118.540 1.00 162.25 ? 72  TRP C CE2 1 
ATOM   3782 C CE3 . TRP C 1 72  ? 136.150 98.399  120.385 1.00 162.25 ? 72  TRP C CE3 1 
ATOM   3783 C CZ2 . TRP C 1 72  ? 137.105 98.892  117.769 1.00 162.25 ? 72  TRP C CZ2 1 
ATOM   3784 C CZ3 . TRP C 1 72  ? 136.702 97.393  119.617 1.00 162.25 ? 72  TRP C CZ3 1 
ATOM   3785 C CH2 . TRP C 1 72  ? 137.174 97.645  118.323 1.00 162.25 ? 72  TRP C CH2 1 
ATOM   3786 N N   . PHE C 1 73  ? 132.897 102.204 119.591 1.00 160.21 ? 73  PHE C N   1 
ATOM   3787 C CA  . PHE C 1 73  ? 132.163 103.240 118.873 1.00 160.21 ? 73  PHE C CA  1 
ATOM   3788 C C   . PHE C 1 73  ? 130.978 102.698 118.089 1.00 160.21 ? 73  PHE C C   1 
ATOM   3789 O O   . PHE C 1 73  ? 130.078 103.475 117.753 1.00 160.21 ? 73  PHE C O   1 
ATOM   3790 C CB  . PHE C 1 73  ? 133.096 104.043 117.961 1.00 160.21 ? 73  PHE C CB  1 
ATOM   3791 C CG  . PHE C 1 73  ? 133.940 105.048 118.701 1.00 160.21 ? 73  PHE C CG  1 
ATOM   3792 C CD1 . PHE C 1 73  ? 135.280 104.822 118.943 1.00 160.21 ? 73  PHE C CD1 1 
ATOM   3793 C CD2 . PHE C 1 73  ? 133.373 106.215 119.179 1.00 160.21 ? 73  PHE C CD2 1 
ATOM   3794 C CE1 . PHE C 1 73  ? 136.046 105.745 119.631 1.00 160.21 ? 73  PHE C CE1 1 
ATOM   3795 C CE2 . PHE C 1 73  ? 134.132 107.142 119.867 1.00 160.21 ? 73  PHE C CE2 1 
ATOM   3796 C CZ  . PHE C 1 73  ? 135.470 106.907 120.094 1.00 160.21 ? 73  PHE C CZ  1 
ATOM   3797 N N   . SER C 1 74  ? 130.920 101.392 117.838 1.00 158.31 ? 74  SER C N   1 
ATOM   3798 C CA  . SER C 1 74  ? 129.647 100.799 117.447 1.00 158.31 ? 74  SER C CA  1 
ATOM   3799 C C   . SER C 1 74  ? 128.594 101.079 118.513 1.00 158.31 ? 74  SER C C   1 
ATOM   3800 O O   . SER C 1 74  ? 127.452 101.442 118.203 1.00 158.31 ? 74  SER C O   1 
ATOM   3801 C CB  . SER C 1 74  ? 129.809 99.296  117.226 1.00 158.31 ? 74  SER C CB  1 
ATOM   3802 O OG  . SER C 1 74  ? 130.758 99.030  116.208 1.00 158.31 ? 74  SER C OG  1 
ATOM   3803 N N   . PHE C 1 75  ? 128.975 100.954 119.784 1.00 156.46 ? 75  PHE C N   1 
ATOM   3804 C CA  . PHE C 1 75  ? 128.027 101.268 120.841 1.00 156.46 ? 75  PHE C CA  1 
ATOM   3805 C C   . PHE C 1 75  ? 127.910 102.767 121.070 1.00 156.46 ? 75  PHE C C   1 
ATOM   3806 O O   . PHE C 1 75  ? 126.876 103.230 121.558 1.00 156.46 ? 75  PHE C O   1 
ATOM   3807 C CB  . PHE C 1 75  ? 128.394 100.541 122.130 1.00 156.46 ? 75  PHE C CB  1 
ATOM   3808 C CG  . PHE C 1 75  ? 127.763 99.188  122.242 1.00 156.46 ? 75  PHE C CG  1 
ATOM   3809 C CD1 . PHE C 1 75  ? 128.017 98.216  121.290 1.00 156.46 ? 75  PHE C CD1 1 
ATOM   3810 C CD2 . PHE C 1 75  ? 126.892 98.895  123.274 1.00 156.46 ? 75  PHE C CD2 1 
ATOM   3811 C CE1 . PHE C 1 75  ? 127.435 96.973  121.378 1.00 156.46 ? 75  PHE C CE1 1 
ATOM   3812 C CE2 . PHE C 1 75  ? 126.304 97.651  123.366 1.00 156.46 ? 75  PHE C CE2 1 
ATOM   3813 C CZ  . PHE C 1 75  ? 126.575 96.689  122.417 1.00 156.46 ? 75  PHE C CZ  1 
ATOM   3814 N N   . ARG C 1 76  ? 128.917 103.560 120.695 1.00 155.93 ? 76  ARG C N   1 
ATOM   3815 C CA  . ARG C 1 76  ? 128.660 104.997 120.692 1.00 155.93 ? 76  ARG C CA  1 
ATOM   3816 C C   . ARG C 1 76  ? 127.555 105.340 119.700 1.00 155.93 ? 76  ARG C C   1 
ATOM   3817 O O   . ARG C 1 76  ? 126.656 106.133 120.002 1.00 155.93 ? 76  ARG C O   1 
ATOM   3818 C CB  . ARG C 1 76  ? 129.914 105.806 120.372 1.00 155.93 ? 76  ARG C CB  1 
ATOM   3819 C CG  . ARG C 1 76  ? 129.671 107.282 120.672 1.00 155.93 ? 76  ARG C CG  1 
ATOM   3820 C CD  . ARG C 1 76  ? 130.803 108.212 120.292 1.00 155.93 ? 76  ARG C CD  1 
ATOM   3821 N NE  . ARG C 1 76  ? 130.928 108.361 118.846 1.00 155.93 ? 76  ARG C NE  1 
ATOM   3822 C CZ  . ARG C 1 76  ? 131.795 109.173 118.253 1.00 155.93 ? 76  ARG C CZ  1 
ATOM   3823 N NH1 . ARG C 1 76  ? 131.842 109.247 116.930 1.00 155.93 ? 76  ARG C NH1 1 
ATOM   3824 N NH2 . ARG C 1 76  ? 132.608 109.923 118.984 1.00 155.93 ? 76  ARG C NH2 1 
ATOM   3825 N N   . GLU C 1 77  ? 127.586 104.663 118.556 1.00 153.56 ? 77  GLU C N   1 
ATOM   3826 C CA  . GLU C 1 77  ? 126.577 104.841 117.527 1.00 153.56 ? 77  GLU C CA  1 
ATOM   3827 C C   . GLU C 1 77  ? 125.220 104.394 118.068 1.00 153.56 ? 77  GLU C C   1 
ATOM   3828 O O   . GLU C 1 77  ? 124.226 105.104 117.914 1.00 153.56 ? 77  GLU C O   1 
ATOM   3829 C CB  . GLU C 1 77  ? 126.936 104.039 116.275 1.00 153.56 ? 77  GLU C CB  1 
ATOM   3830 C CG  . GLU C 1 77  ? 125.752 103.347 115.620 1.00 153.56 ? 77  GLU C CG  1 
ATOM   3831 C CD  . GLU C 1 77  ? 125.269 104.068 114.377 1.00 153.56 ? 77  GLU C CD  1 
ATOM   3832 O OE1 . GLU C 1 77  ? 125.262 105.317 114.378 1.00 153.56 ? 77  GLU C OE1 1 
ATOM   3833 O OE2 . GLU C 1 77  ? 124.895 103.388 113.399 1.00 153.56 ? 77  GLU C OE2 1 
ATOM   3834 N N   . ILE C 1 78  ? 125.175 103.222 118.702 1.00 148.64 ? 78  ILE C N   1 
ATOM   3835 C CA  . ILE C 1 78  ? 123.918 102.738 119.262 1.00 148.64 ? 78  ILE C CA  1 
ATOM   3836 C C   . ILE C 1 78  ? 123.408 103.697 120.328 1.00 148.64 ? 78  ILE C C   1 
ATOM   3837 O O   . ILE C 1 78  ? 122.193 103.789 120.537 1.00 148.64 ? 78  ILE C O   1 
ATOM   3838 C CB  . ILE C 1 78  ? 124.047 101.316 119.835 1.00 148.64 ? 78  ILE C CB  1 
ATOM   3839 C CG1 . ILE C 1 78  ? 122.687 100.630 119.837 1.00 148.64 ? 78  ILE C CG1 1 
ATOM   3840 C CG2 . ILE C 1 78  ? 124.511 101.336 121.268 1.00 148.64 ? 78  ILE C CG2 1 
ATOM   3841 C CD1 . ILE C 1 78  ? 122.177 100.331 118.456 1.00 148.64 ? 78  ILE C CD1 1 
ATOM   3842 N N   . SER C 1 79  ? 124.307 104.424 121.001 1.00 145.51 ? 79  SER C N   1 
ATOM   3843 C CA  . SER C 1 79  ? 123.882 105.487 121.904 1.00 145.51 ? 79  SER C CA  1 
ATOM   3844 C C   . SER C 1 79  ? 123.284 106.649 121.125 1.00 145.51 ? 79  SER C C   1 
ATOM   3845 O O   . SER C 1 79  ? 122.334 107.292 121.582 1.00 145.51 ? 79  SER C O   1 
ATOM   3846 C CB  . SER C 1 79  ? 125.054 105.968 122.755 1.00 145.51 ? 79  SER C CB  1 
ATOM   3847 O OG  . SER C 1 79  ? 125.903 106.817 122.009 1.00 145.51 ? 79  SER C OG  1 
ATOM   3848 N N   . TYR C 1 80  ? 123.783 106.862 119.913 1.00 149.87 ? 80  TYR C N   1 
ATOM   3849 C CA  . TYR C 1 80  ? 123.244 107.903 119.053 1.00 149.87 ? 80  TYR C CA  1 
ATOM   3850 C C   . TYR C 1 80  ? 121.827 107.482 118.665 1.00 149.87 ? 80  TYR C C   1 
ATOM   3851 O O   . TYR C 1 80  ? 120.973 108.321 118.372 1.00 149.87 ? 80  TYR C O   1 
ATOM   3852 C CB  . TYR C 1 80  ? 124.108 108.077 117.805 1.00 149.87 ? 80  TYR C CB  1 
ATOM   3853 C CG  . TYR C 1 80  ? 123.352 108.608 116.609 1.00 149.87 ? 80  TYR C CG  1 
ATOM   3854 C CD1 . TYR C 1 80  ? 122.621 107.756 115.792 1.00 149.87 ? 80  TYR C CD1 1 
ATOM   3855 C CD2 . TYR C 1 80  ? 123.371 109.960 116.296 1.00 149.87 ? 80  TYR C CD2 1 
ATOM   3856 C CE1 . TYR C 1 80  ? 121.927 108.237 114.697 1.00 149.87 ? 80  TYR C CE1 1 
ATOM   3857 C CE2 . TYR C 1 80  ? 122.681 110.450 115.203 1.00 149.87 ? 80  TYR C CE2 1 
ATOM   3858 C CZ  . TYR C 1 80  ? 121.961 109.584 114.407 1.00 149.87 ? 80  TYR C CZ  1 
ATOM   3859 O OH  . TYR C 1 80  ? 121.274 110.068 113.317 1.00 149.87 ? 80  TYR C OH  1 
ATOM   3860 N N   . ARG C 1 81  ? 121.591 106.171 118.668 1.00 143.82 ? 81  ARG C N   1 
ATOM   3861 C CA  . ARG C 1 81  ? 120.290 105.605 118.340 1.00 143.82 ? 81  ARG C CA  1 
ATOM   3862 C C   . ARG C 1 81  ? 119.394 105.575 119.580 1.00 143.82 ? 81  ARG C C   1 
ATOM   3863 O O   . ARG C 1 81  ? 118.169 105.530 119.468 1.00 143.82 ? 81  ARG C O   1 
ATOM   3864 C CB  . ARG C 1 81  ? 120.446 104.196 117.768 1.00 143.82 ? 81  ARG C CB  1 
ATOM   3865 C CG  . ARG C 1 81  ? 120.029 104.070 116.312 1.00 143.82 ? 81  ARG C CG  1 
ATOM   3866 C CD  . ARG C 1 81  ? 118.730 104.812 116.042 1.00 143.82 ? 81  ARG C CD  1 
ATOM   3867 N NE  . ARG C 1 81  ? 118.870 105.788 114.966 1.00 143.82 ? 81  ARG C NE  1 
ATOM   3868 C CZ  . ARG C 1 81  ? 118.014 105.916 113.957 1.00 143.82 ? 81  ARG C CZ  1 
ATOM   3869 N NH1 . ARG C 1 81  ? 116.951 105.126 113.883 1.00 143.82 ? 81  ARG C NH1 1 
ATOM   3870 N NH2 . ARG C 1 81  ? 118.221 106.832 113.021 1.00 143.82 ? 81  ARG C NH2 1 
ATOM   3871 N N   . HIS C 1 82  ? 120.011 105.601 120.760 1.00 132.44 ? 82  HIS C N   1 
ATOM   3872 C CA  . HIS C 1 82  ? 119.266 105.582 122.023 1.00 132.44 ? 82  HIS C CA  1 
ATOM   3873 C C   . HIS C 1 82  ? 120.042 106.454 123.012 1.00 132.44 ? 82  HIS C C   1 
ATOM   3874 O O   . HIS C 1 82  ? 120.952 106.002 123.706 1.00 132.44 ? 82  HIS C O   1 
ATOM   3875 C CB  . HIS C 1 82  ? 119.069 104.165 122.562 1.00 132.44 ? 82  HIS C CB  1 
ATOM   3876 C CG  . HIS C 1 82  ? 118.068 103.361 121.796 1.00 132.44 ? 82  HIS C CG  1 
ATOM   3877 N ND1 . HIS C 1 82  ? 117.128 103.935 120.968 1.00 132.44 ? 82  HIS C ND1 1 
ATOM   3878 C CD2 . HIS C 1 82  ? 117.852 102.025 121.739 1.00 132.44 ? 82  HIS C CD2 1 
ATOM   3879 C CE1 . HIS C 1 82  ? 116.381 102.989 120.429 1.00 132.44 ? 82  HIS C CE1 1 
ATOM   3880 N NE2 . HIS C 1 82  ? 116.799 101.821 120.881 1.00 132.44 ? 82  HIS C NE2 1 
ATOM   3881 N N   . ALA C 1 83  ? 119.662 107.729 123.077 1.00 121.58 ? 83  ALA C N   1 
ATOM   3882 C CA  . ALA C 1 83  ? 120.429 108.733 123.808 1.00 121.58 ? 83  ALA C CA  1 
ATOM   3883 C C   . ALA C 1 83  ? 120.515 108.444 125.301 1.00 121.58 ? 83  ALA C C   1 
ATOM   3884 O O   . ALA C 1 83  ? 121.546 108.699 125.930 1.00 121.58 ? 83  ALA C O   1 
ATOM   3885 C CB  . ALA C 1 83  ? 119.824 110.118 123.585 1.00 121.58 ? 83  ALA C CB  1 
ATOM   3886 N N   . TRP C 1 84  ? 119.440 107.916 125.874 1.00 112.57 ? 84  TRP C N   1 
ATOM   3887 C CA  . TRP C 1 84  ? 119.321 107.736 127.316 1.00 112.57 ? 84  TRP C CA  1 
ATOM   3888 C C   . TRP C 1 84  ? 120.234 106.653 127.875 1.00 112.57 ? 84  TRP C C   1 
ATOM   3889 O O   . TRP C 1 84  ? 120.357 106.517 129.099 1.00 112.57 ? 84  TRP C O   1 
ATOM   3890 C CB  . TRP C 1 84  ? 117.876 107.396 127.662 1.00 112.57 ? 84  TRP C CB  1 
ATOM   3891 C CG  . TRP C 1 84  ? 117.326 106.325 126.795 1.00 112.57 ? 84  TRP C CG  1 
ATOM   3892 C CD1 . TRP C 1 84  ? 116.651 106.488 125.628 1.00 112.57 ? 84  TRP C CD1 1 
ATOM   3893 C CD2 . TRP C 1 84  ? 117.409 104.917 127.019 1.00 112.57 ? 84  TRP C CD2 1 
ATOM   3894 N NE1 . TRP C 1 84  ? 116.303 105.269 125.108 1.00 112.57 ? 84  TRP C NE1 1 
ATOM   3895 C CE2 . TRP C 1 84  ? 116.758 104.286 125.945 1.00 112.57 ? 84  TRP C CE2 1 
ATOM   3896 C CE3 . TRP C 1 84  ? 117.968 104.128 128.025 1.00 112.57 ? 84  TRP C CE3 1 
ATOM   3897 C CZ2 . TRP C 1 84  ? 116.647 102.903 125.850 1.00 112.57 ? 84  TRP C CZ2 1 
ATOM   3898 C CZ3 . TRP C 1 84  ? 117.859 102.757 127.927 1.00 112.57 ? 84  TRP C CZ3 1 
ATOM   3899 C CH2 . TRP C 1 84  ? 117.204 102.158 126.849 1.00 112.57 ? 84  TRP C CH2 1 
ATOM   3900 N N   . ILE C 1 85  ? 120.865 105.872 127.000 1.00 111.40 ? 85  ILE C N   1 
ATOM   3901 C CA  . ILE C 1 85  ? 121.504 104.640 127.447 1.00 111.40 ? 85  ILE C CA  1 
ATOM   3902 C C   . ILE C 1 85  ? 122.682 104.901 128.387 1.00 111.40 ? 85  ILE C C   1 
ATOM   3903 O O   . ILE C 1 85  ? 122.847 104.185 129.377 1.00 111.40 ? 85  ILE C O   1 
ATOM   3904 C CB  . ILE C 1 85  ? 121.913 103.782 126.238 1.00 111.40 ? 85  ILE C CB  1 
ATOM   3905 C CG1 . ILE C 1 85  ? 122.292 102.375 126.696 1.00 111.40 ? 85  ILE C CG1 1 
ATOM   3906 C CG2 . ILE C 1 85  ? 123.041 104.419 125.451 1.00 111.40 ? 85  ILE C CG2 1 
ATOM   3907 C CD1 . ILE C 1 85  ? 121.136 101.601 127.271 1.00 111.40 ? 85  ILE C CD1 1 
ATOM   3908 N N   . ALA C 1 86  ? 123.521 105.900 128.110 1.00 107.09 ? 86  ALA C N   1 
ATOM   3909 C CA  . ALA C 1 86  ? 124.639 106.176 129.012 1.00 107.09 ? 86  ALA C CA  1 
ATOM   3910 C C   . ALA C 1 86  ? 124.184 106.649 130.389 1.00 107.09 ? 86  ALA C C   1 
ATOM   3911 O O   . ALA C 1 86  ? 124.717 106.148 131.398 1.00 107.09 ? 86  ALA C O   1 
ATOM   3912 C CB  . ALA C 1 86  ? 125.598 107.174 128.357 1.00 107.09 ? 86  ALA C CB  1 
ATOM   3913 N N   . PRO C 1 87  ? 123.254 107.604 130.519 1.00 103.95 ? 87  PRO C N   1 
ATOM   3914 C CA  . PRO C 1 87  ? 122.724 107.902 131.857 1.00 103.95 ? 87  PRO C CA  1 
ATOM   3915 C C   . PRO C 1 87  ? 122.106 106.695 132.531 1.00 103.95 ? 87  PRO C C   1 
ATOM   3916 O O   . PRO C 1 87  ? 122.262 106.527 133.745 1.00 103.95 ? 87  PRO C O   1 
ATOM   3917 C CB  . PRO C 1 87  ? 121.697 109.001 131.577 1.00 103.95 ? 87  PRO C CB  1 
ATOM   3918 C CG  . PRO C 1 87  ? 122.200 109.665 130.371 1.00 103.95 ? 87  PRO C CG  1 
ATOM   3919 C CD  . PRO C 1 87  ? 122.736 108.559 129.524 1.00 103.95 ? 87  PRO C CD  1 
ATOM   3920 N N   . LEU C 1 88  ? 121.413 105.834 131.783 1.00 103.49 ? 88  LEU C N   1 
ATOM   3921 C CA  . LEU C 1 88  ? 120.862 104.645 132.422 1.00 103.49 ? 88  LEU C CA  1 
ATOM   3922 C C   . LEU C 1 88  ? 121.972 103.751 132.951 1.00 103.49 ? 88  LEU C C   1 
ATOM   3923 O O   . LEU C 1 88  ? 121.845 103.174 134.033 1.00 103.49 ? 88  LEU C O   1 
ATOM   3924 C CB  . LEU C 1 88  ? 119.967 103.865 131.466 1.00 103.49 ? 88  LEU C CB  1 
ATOM   3925 C CG  . LEU C 1 88  ? 119.371 102.633 132.150 1.00 103.49 ? 88  LEU C CG  1 
ATOM   3926 C CD1 . LEU C 1 88  ? 118.633 103.048 133.398 1.00 103.49 ? 88  LEU C CD1 1 
ATOM   3927 C CD2 . LEU C 1 88  ? 118.453 101.860 131.231 1.00 103.49 ? 88  LEU C CD2 1 
ATOM   3928 N N   . MET C 1 89  ? 123.071 103.677 132.206 1.00 105.51 ? 89  MET C N   1 
ATOM   3929 C CA  . MET C 1 89  ? 124.217 102.872 132.609 1.00 105.51 ? 89  MET C CA  1 
ATOM   3930 C C   . MET C 1 89  ? 124.816 103.401 133.909 1.00 105.51 ? 89  MET C C   1 
ATOM   3931 O O   . MET C 1 89  ? 125.146 102.628 134.808 1.00 105.51 ? 89  MET C O   1 
ATOM   3932 C CB  . MET C 1 89  ? 125.278 102.859 131.507 1.00 105.51 ? 89  MET C CB  1 
ATOM   3933 C CG  . MET C 1 89  ? 124.909 102.009 130.301 1.00 105.51 ? 89  MET C CG  1 
ATOM   3934 S SD  . MET C 1 89  ? 125.018 100.241 130.636 1.00 105.51 ? 89  MET C SD  1 
ATOM   3935 C CE  . MET C 1 89  ? 124.383 99.567  129.102 1.00 105.51 ? 89  MET C CE  1 
ATOM   3936 N N   . ILE C 1 90  ? 124.957 104.722 134.006 1.00 100.15 ? 90  ILE C N   1 
ATOM   3937 C CA  . ILE C 1 90  ? 125.515 105.338 135.209 1.00 100.15 ? 90  ILE C CA  1 
ATOM   3938 C C   . ILE C 1 90  ? 124.595 105.113 136.401 1.00 100.15 ? 90  ILE C C   1 
ATOM   3939 O O   . ILE C 1 90  ? 125.038 104.726 137.493 1.00 100.15 ? 90  ILE C O   1 
ATOM   3940 C CB  . ILE C 1 90  ? 125.777 106.835 134.976 1.00 100.15 ? 90  ILE C CB  1 
ATOM   3941 C CG1 . ILE C 1 90  ? 126.848 107.029 133.904 1.00 100.15 ? 90  ILE C CG1 1 
ATOM   3942 C CG2 . ILE C 1 90  ? 126.186 107.503 136.270 1.00 100.15 ? 90  ILE C CG2 1 
ATOM   3943 C CD1 . ILE C 1 90  ? 127.357 108.450 133.801 1.00 100.15 ? 90  ILE C CD1 1 
ATOM   3944 N N   . LEU C 1 91  ? 123.295 105.341 136.210 1.00 95.53  ? 91  LEU C N   1 
ATOM   3945 C CA  . LEU C 1 91  ? 122.336 105.130 137.288 1.00 95.53  ? 91  LEU C CA  1 
ATOM   3946 C C   . LEU C 1 91  ? 122.325 103.683 137.755 1.00 95.53  ? 91  LEU C C   1 
ATOM   3947 O O   . LEU C 1 91  ? 122.308 103.411 138.959 1.00 95.53  ? 91  LEU C O   1 
ATOM   3948 C CB  . LEU C 1 91  ? 120.940 105.551 136.841 1.00 95.53  ? 91  LEU C CB  1 
ATOM   3949 C CG  . LEU C 1 91  ? 120.507 106.989 137.074 1.00 95.53  ? 91  LEU C CG  1 
ATOM   3950 C CD1 . LEU C 1 91  ? 121.270 107.966 136.230 1.00 95.53  ? 91  LEU C CD1 1 
ATOM   3951 C CD2 . LEU C 1 91  ? 119.047 107.048 136.747 1.00 95.53  ? 91  LEU C CD2 1 
ATOM   3952 N N   . ILE C 1 92  ? 122.301 102.737 136.818 1.00 101.51 ? 92  ILE C N   1 
ATOM   3953 C CA  . ILE C 1 92  ? 122.200 101.341 137.218 1.00 101.51 ? 92  ILE C CA  1 
ATOM   3954 C C   . ILE C 1 92  ? 123.469 100.906 137.930 1.00 101.51 ? 92  ILE C C   1 
ATOM   3955 O O   . ILE C 1 92  ? 123.410 100.144 138.900 1.00 101.51 ? 92  ILE C O   1 
ATOM   3956 C CB  . ILE C 1 92  ? 121.862 100.442 136.010 1.00 101.51 ? 92  ILE C CB  1 
ATOM   3957 C CG1 . ILE C 1 92  ? 121.382 99.075  136.491 1.00 101.51 ? 92  ILE C CG1 1 
ATOM   3958 C CG2 . ILE C 1 92  ? 123.042 100.293 135.069 1.00 101.51 ? 92  ILE C CG2 1 
ATOM   3959 C CD1 . ILE C 1 92  ? 120.080 99.130  137.251 1.00 101.51 ? 92  ILE C CD1 1 
ATOM   3960 N N   . ALA C 1 93  ? 124.628 101.418 137.506 1.00 101.60 ? 93  ALA C N   1 
ATOM   3961 C CA  . ALA C 1 93  ? 125.868 101.093 138.198 1.00 101.60 ? 93  ALA C CA  1 
ATOM   3962 C C   . ALA C 1 93  ? 125.855 101.622 139.626 1.00 101.60 ? 93  ALA C C   1 
ATOM   3963 O O   . ALA C 1 93  ? 126.181 100.893 140.571 1.00 101.60 ? 93  ALA C O   1 
ATOM   3964 C CB  . ALA C 1 93  ? 127.062 101.652 137.427 1.00 101.60 ? 93  ALA C CB  1 
ATOM   3965 N N   . VAL C 1 94  ? 125.469 102.889 139.808 1.00 97.01  ? 94  VAL C N   1 
ATOM   3966 C CA  . VAL C 1 94  ? 125.486 103.464 141.153 1.00 97.01  ? 94  VAL C CA  1 
ATOM   3967 C C   . VAL C 1 94  ? 124.465 102.778 142.051 1.00 97.01  ? 94  VAL C C   1 
ATOM   3968 O O   . VAL C 1 94  ? 124.759 102.436 143.202 1.00 97.01  ? 94  VAL C O   1 
ATOM   3969 C CB  . VAL C 1 94  ? 125.263 104.983 141.097 1.00 97.01  ? 94  VAL C CB  1 
ATOM   3970 C CG1 . VAL C 1 94  ? 124.996 105.516 142.482 1.00 97.01  ? 94  VAL C CG1 1 
ATOM   3971 C CG2 . VAL C 1 94  ? 126.474 105.664 140.509 1.00 97.01  ? 94  VAL C CG2 1 
ATOM   3972 N N   . TYR C 1 95  ? 123.252 102.560 141.543 1.00 96.49  ? 95  TYR C N   1 
ATOM   3973 C CA  . TYR C 1 95  ? 122.237 101.884 142.340 1.00 96.49  ? 95  TYR C CA  1 
ATOM   3974 C C   . TYR C 1 95  ? 122.665 100.468 142.687 1.00 96.49  ? 95  TYR C C   1 
ATOM   3975 O O   . TYR C 1 95  ? 122.429 100.000 143.806 1.00 96.49  ? 95  TYR C O   1 
ATOM   3976 C CB  . TYR C 1 95  ? 120.904 101.864 141.599 1.00 96.49  ? 95  TYR C CB  1 
ATOM   3977 C CG  . TYR C 1 95  ? 120.055 103.090 141.813 1.00 96.49  ? 95  TYR C CG  1 
ATOM   3978 C CD1 . TYR C 1 95  ? 120.508 104.344 141.456 1.00 96.49  ? 95  TYR C CD1 1 
ATOM   3979 C CD2 . TYR C 1 95  ? 118.793 102.990 142.370 1.00 96.49  ? 95  TYR C CD2 1 
ATOM   3980 C CE1 . TYR C 1 95  ? 119.733 105.461 141.648 1.00 96.49  ? 95  TYR C CE1 1 
ATOM   3981 C CE2 . TYR C 1 95  ? 118.010 104.104 142.567 1.00 96.49  ? 95  TYR C CE2 1 
ATOM   3982 C CZ  . TYR C 1 95  ? 118.487 105.336 142.203 1.00 96.49  ? 95  TYR C CZ  1 
ATOM   3983 O OH  . TYR C 1 95  ? 117.714 106.452 142.397 1.00 96.49  ? 95  TYR C OH  1 
ATOM   3984 N N   . SER C 1 96  ? 123.286 99.766  141.740 1.00 103.00 ? 96  SER C N   1 
ATOM   3985 C CA  . SER C 1 96  ? 123.738 98.408  141.996 1.00 103.00 ? 96  SER C CA  1 
ATOM   3986 C C   . SER C 1 96  ? 124.809 98.389  143.073 1.00 103.00 ? 96  SER C C   1 
ATOM   3987 O O   . SER C 1 96  ? 124.781 97.551  143.981 1.00 103.00 ? 96  SER C O   1 
ATOM   3988 C CB  . SER C 1 96  ? 124.259 97.801  140.699 1.00 103.00 ? 96  SER C CB  1 
ATOM   3989 O OG  . SER C 1 96  ? 123.321 97.993  139.656 1.00 103.00 ? 96  SER C OG  1 
ATOM   3990 N N   . ALA C 1 97  ? 125.755 99.324  143.000 1.00 103.88 ? 97  ALA C N   1 
ATOM   3991 C CA  . ALA C 1 97  ? 126.794 99.396  144.017 1.00 103.88 ? 97  ALA C CA  1 
ATOM   3992 C C   . ALA C 1 97  ? 126.197 99.694  145.387 1.00 103.88 ? 97  ALA C C   1 
ATOM   3993 O O   . ALA C 1 97  ? 126.607 99.114  146.397 1.00 103.88 ? 97  ALA C O   1 
ATOM   3994 C CB  . ALA C 1 97  ? 127.831 100.449 143.631 1.00 103.88 ? 97  ALA C CB  1 
ATOM   3995 N N   . TYR C 1 98  ? 125.213 100.594 145.441 1.00 102.99 ? 98  TYR C N   1 
ATOM   3996 C CA  . TYR C 1 98  ? 124.633 100.954 146.732 1.00 102.99 ? 98  TYR C CA  1 
ATOM   3997 C C   . TYR C 1 98  ? 123.796 99.825  147.312 1.00 102.99 ? 98  TYR C C   1 
ATOM   3998 O O   . TYR C 1 98  ? 123.786 99.631  148.531 1.00 102.99 ? 98  TYR C O   1 
ATOM   3999 C CB  . TYR C 1 98  ? 123.793 102.223 146.602 1.00 102.99 ? 98  TYR C CB  1 
ATOM   4000 C CG  . TYR C 1 98  ? 123.014 102.585 147.846 1.00 102.99 ? 98  TYR C CG  1 
ATOM   4001 C CD1 . TYR C 1 98  ? 123.592 103.342 148.849 1.00 102.99 ? 98  TYR C CD1 1 
ATOM   4002 C CD2 . TYR C 1 98  ? 121.691 102.202 148.002 1.00 102.99 ? 98  TYR C CD2 1 
ATOM   4003 C CE1 . TYR C 1 98  ? 122.889 103.682 149.979 1.00 102.99 ? 98  TYR C CE1 1 
ATOM   4004 C CE2 . TYR C 1 98  ? 120.981 102.541 149.131 1.00 102.99 ? 98  TYR C CE2 1 
ATOM   4005 C CZ  . TYR C 1 98  ? 121.585 103.281 150.115 1.00 102.99 ? 98  TYR C CZ  1 
ATOM   4006 O OH  . TYR C 1 98  ? 120.883 103.624 151.245 1.00 102.99 ? 98  TYR C OH  1 
ATOM   4007 N N   . PHE C 1 99  ? 123.089 99.075  146.473 1.00 106.72 ? 99  PHE C N   1 
ATOM   4008 C CA  . PHE C 1 99  ? 122.162 98.077  146.984 1.00 106.72 ? 99  PHE C CA  1 
ATOM   4009 C C   . PHE C 1 99  ? 122.803 96.719  147.222 1.00 106.72 ? 99  PHE C C   1 
ATOM   4010 O O   . PHE C 1 99  ? 122.358 95.985  148.111 1.00 106.72 ? 99  PHE C O   1 
ATOM   4011 C CB  . PHE C 1 99  ? 120.977 97.927  146.031 1.00 106.72 ? 99  PHE C CB  1 
ATOM   4012 C CG  . PHE C 1 99  ? 119.948 99.002  146.187 1.00 106.72 ? 99  PHE C CG  1 
ATOM   4013 C CD1 . PHE C 1 99  ? 119.469 99.337  147.442 1.00 106.72 ? 99  PHE C CD1 1 
ATOM   4014 C CD2 . PHE C 1 99  ? 119.470 99.687  145.089 1.00 106.72 ? 99  PHE C CD2 1 
ATOM   4015 C CE1 . PHE C 1 99  ? 118.528 100.328 147.598 1.00 106.72 ? 99  PHE C CE1 1 
ATOM   4016 C CE2 . PHE C 1 99  ? 118.528 100.678 145.238 1.00 106.72 ? 99  PHE C CE2 1 
ATOM   4017 C CZ  . PHE C 1 99  ? 118.057 100.999 146.495 1.00 106.72 ? 99  PHE C CZ  1 
ATOM   4018 N N   . THR C 1 100 ? 123.832 96.356  146.454 1.00 110.21 ? 100 THR C N   1 
ATOM   4019 C CA  . THR C 1 100 ? 124.506 95.087  146.701 1.00 110.21 ? 100 THR C CA  1 
ATOM   4020 C C   . THR C 1 100 ? 125.443 95.177  147.896 1.00 110.21 ? 100 THR C C   1 
ATOM   4021 O O   . THR C 1 100 ? 125.847 94.150  148.449 1.00 110.21 ? 100 THR C O   1 
ATOM   4022 C CB  . THR C 1 100 ? 125.283 94.644  145.466 1.00 110.21 ? 100 THR C CB  1 
ATOM   4023 O OG1 . THR C 1 100 ? 126.285 95.620  145.158 1.00 110.21 ? 100 THR C OG1 1 
ATOM   4024 C CG2 . THR C 1 100 ? 124.348 94.470  144.279 1.00 110.21 ? 100 THR C CG2 1 
ATOM   4025 N N   . SER C 1 101 ? 125.799 96.393  148.306 1.00 112.44 ? 101 SER C N   1 
ATOM   4026 C CA  . SER C 1 101 ? 126.725 96.582  149.414 1.00 112.44 ? 101 SER C CA  1 
ATOM   4027 C C   . SER C 1 101 ? 126.132 96.079  150.723 1.00 112.44 ? 101 SER C C   1 
ATOM   4028 O O   . SER C 1 101 ? 126.865 95.832  151.687 1.00 112.44 ? 101 SER C O   1 
ATOM   4029 C CB  . SER C 1 101 ? 127.111 98.054  149.538 1.00 112.44 ? 101 SER C CB  1 
ATOM   4030 O OG  . SER C 1 101 ? 127.542 98.570  148.292 1.00 112.44 ? 101 SER C OG  1 
ATOM   4031 N N   . GLY C 1 102 ? 124.814 95.932  150.772 1.00 115.95 ? 102 GLY C N   1 
ATOM   4032 C CA  . GLY C 1 102 ? 124.174 95.444  151.974 1.00 115.95 ? 102 GLY C CA  1 
ATOM   4033 C C   . GLY C 1 102 ? 123.948 96.526  153.009 1.00 115.95 ? 102 GLY C C   1 
ATOM   4034 O O   . GLY C 1 102 ? 122.819 96.727  153.467 1.00 115.95 ? 102 GLY C O   1 
ATOM   4035 N N   . ASN C 1 103 ? 125.011 97.237  153.385 1.00 118.73 ? 103 ASN C N   1 
ATOM   4036 C CA  . ASN C 1 103 ? 124.926 98.275  154.412 1.00 118.73 ? 103 ASN C CA  1 
ATOM   4037 C C   . ASN C 1 103 ? 124.267 99.528  153.844 1.00 118.73 ? 103 ASN C C   1 
ATOM   4038 O O   . ASN C 1 103 ? 124.841 100.618 153.827 1.00 118.73 ? 103 ASN C O   1 
ATOM   4039 C CB  . ASN C 1 103 ? 126.305 98.561  154.996 1.00 118.73 ? 103 ASN C CB  1 
ATOM   4040 C CG  . ASN C 1 103 ? 127.288 99.114  153.976 1.00 118.73 ? 103 ASN C CG  1 
ATOM   4041 O OD1 . ASN C 1 103 ? 126.936 99.408  152.834 1.00 118.73 ? 103 ASN C OD1 1 
ATOM   4042 N ND2 . ASN C 1 103 ? 128.536 99.273  154.397 1.00 118.73 ? 103 ASN C ND2 1 
ATOM   4043 N N   . THR C 1 104 ? 123.017 99.384  153.422 1.00 114.81 ? 104 THR C N   1 
ATOM   4044 C CA  . THR C 1 104 ? 122.216 100.503 152.942 1.00 114.81 ? 104 THR C CA  1 
ATOM   4045 C C   . THR C 1 104 ? 121.889 101.343 154.173 1.00 114.81 ? 104 THR C C   1 
ATOM   4046 O O   . THR C 1 104 ? 120.767 101.318 154.684 1.00 114.81 ? 104 THR C O   1 
ATOM   4047 C CB  . THR C 1 104 ? 120.961 100.024 152.240 1.00 114.81 ? 104 THR C CB  1 
ATOM   4048 O OG1 . THR C 1 104 ? 120.058 99.471  153.204 1.00 114.81 ? 104 THR C OG1 1 
ATOM   4049 C CG2 . THR C 1 104 ? 121.315 98.952  151.223 1.00 114.81 ? 104 THR C CG2 1 
ATOM   4050 N N   . THR C 1 105 ? 122.886 102.080 154.653 1.00 112.08 ? 105 THR C N   1 
ATOM   4051 C CA  . THR C 1 105 ? 122.771 102.821 155.897 1.00 112.08 ? 105 THR C CA  1 
ATOM   4052 C C   . THR C 1 105 ? 122.891 104.303 155.587 1.00 112.08 ? 105 THR C C   1 
ATOM   4053 O O   . THR C 1 105 ? 122.998 104.708 154.430 1.00 112.08 ? 105 THR C O   1 
ATOM   4054 C CB  . THR C 1 105 ? 123.841 102.389 156.901 1.00 112.08 ? 105 THR C CB  1 
ATOM   4055 O OG1 . THR C 1 105 ? 125.138 102.668 156.362 1.00 112.08 ? 105 THR C OG1 1 
ATOM   4056 C CG2 . THR C 1 105 ? 123.733 100.900 157.170 1.00 112.08 ? 105 THR C CG2 1 
ATOM   4057 N N   . LYS C 1 106 ? 122.880 105.117 156.643 1.00 108.41 ? 106 LYS C N   1 
ATOM   4058 C CA  . LYS C 1 106 ? 123.025 106.551 156.447 1.00 108.41 ? 106 LYS C CA  1 
ATOM   4059 C C   . LYS C 1 106 ? 124.451 106.933 156.103 1.00 108.41 ? 106 LYS C C   1 
ATOM   4060 O O   . LYS C 1 106 ? 124.740 108.122 155.934 1.00 108.41 ? 106 LYS C O   1 
ATOM   4061 C CB  . LYS C 1 106 ? 122.583 107.321 157.691 1.00 108.41 ? 106 LYS C CB  1 
ATOM   4062 C CG  . LYS C 1 106 ? 123.460 107.116 158.905 1.00 108.41 ? 106 LYS C CG  1 
ATOM   4063 C CD  . LYS C 1 106 ? 122.906 107.878 160.096 1.00 108.41 ? 106 LYS C CD  1 
ATOM   4064 C CE  . LYS C 1 106 ? 123.053 109.374 159.906 1.00 108.41 ? 106 LYS C CE  1 
ATOM   4065 N NZ  . LYS C 1 106 ? 124.483 109.783 159.892 1.00 108.41 ? 106 LYS C NZ  1 
ATOM   4066 N N   . THR C 1 107 ? 125.387 105.981 156.201 1.00 109.90 ? 107 THR C N   1 
ATOM   4067 C CA  . THR C 1 107 ? 126.827 106.237 155.966 1.00 109.90 ? 107 THR C CA  1 
ATOM   4068 C C   . THR C 1 107 ? 127.278 105.637 154.644 1.00 109.90 ? 107 THR C C   1 
ATOM   4069 O O   . THR C 1 107 ? 126.419 105.378 153.802 1.00 109.90 ? 107 THR C O   1 
ATOM   4070 C CB  . THR C 1 107 ? 127.696 105.671 157.103 1.00 109.90 ? 107 THR C CB  1 
ATOM   4071 O OG1 . THR C 1 107 ? 129.077 105.715 156.722 1.00 109.90 ? 107 THR C OG1 1 
ATOM   4072 C CG2 . THR C 1 107 ? 127.306 104.232 157.404 1.00 109.90 ? 107 THR C CG2 1 
ATOM   4073 N N   . ASN C 1 108 ? 128.581 105.443 154.455 1.00 105.47 ? 108 ASN C N   1 
ATOM   4074 C CA  . ASN C 1 108 ? 129.108 104.965 153.179 1.00 105.47 ? 108 ASN C CA  1 
ATOM   4075 C C   . ASN C 1 108 ? 129.244 106.233 152.334 1.00 105.47 ? 108 ASN C C   1 
ATOM   4076 O O   . ASN C 1 108 ? 129.582 107.291 152.869 1.00 105.47 ? 108 ASN C O   1 
ATOM   4077 C CB  . ASN C 1 108 ? 128.142 103.982 152.523 1.00 105.47 ? 108 ASN C CB  1 
ATOM   4078 C CG  . ASN C 1 108 ? 128.853 102.944 151.676 1.00 105.47 ? 108 ASN C CG  1 
ATOM   4079 O OD1 . ASN C 1 108 ? 128.276 102.391 150.739 1.00 105.47 ? 108 ASN C OD1 1 
ATOM   4080 N ND2 . ASN C 1 108 ? 130.112 102.676 152.001 1.00 105.47 ? 108 ASN C ND2 1 
ATOM   4081 N N   . VAL C 1 109 ? 129.013 106.164 151.025 1.00 99.43  ? 109 VAL C N   1 
ATOM   4082 C CA  . VAL C 1 109 ? 129.081 107.414 150.274 1.00 99.43  ? 109 VAL C CA  1 
ATOM   4083 C C   . VAL C 1 109 ? 127.805 107.467 149.438 1.00 99.43  ? 109 VAL C C   1 
ATOM   4084 O O   . VAL C 1 109 ? 127.096 108.486 149.358 1.00 99.43  ? 109 VAL C O   1 
ATOM   4085 C CB  . VAL C 1 109 ? 130.356 107.523 149.413 1.00 99.43  ? 109 VAL C CB  1 
ATOM   4086 C CG1 . VAL C 1 109 ? 131.552 107.818 150.274 1.00 99.43  ? 109 VAL C CG1 1 
ATOM   4087 C CG2 . VAL C 1 109 ? 130.617 106.238 148.695 1.00 99.43  ? 109 VAL C CG2 1 
ATOM   4088 N N   . LEU C 1 110 ? 127.535 106.344 148.772 1.00 98.57  ? 110 LEU C N   1 
ATOM   4089 C CA  . LEU C 1 110 ? 126.439 106.291 147.823 1.00 98.57  ? 110 LEU C CA  1 
ATOM   4090 C C   . LEU C 1 110 ? 125.133 106.684 148.486 1.00 98.57  ? 110 LEU C C   1 
ATOM   4091 O O   . LEU C 1 110 ? 124.209 107.147 147.816 1.00 98.57  ? 110 LEU C O   1 
ATOM   4092 C CB  . LEU C 1 110 ? 126.331 104.900 147.213 1.00 98.57  ? 110 LEU C CB  1 
ATOM   4093 C CG  . LEU C 1 110 ? 127.372 104.557 146.151 1.00 98.57  ? 110 LEU C CG  1 
ATOM   4094 C CD1 . LEU C 1 110 ? 128.660 104.094 146.782 1.00 98.57  ? 110 LEU C CD1 1 
ATOM   4095 C CD2 . LEU C 1 110 ? 126.849 103.504 145.223 1.00 98.57  ? 110 LEU C CD2 1 
ATOM   4096 N N   . HIS C 1 111 ? 125.036 106.518 149.805 1.00 96.90  ? 111 HIS C N   1 
ATOM   4097 C CA  . HIS C 1 111 ? 123.863 107.028 150.498 1.00 96.90  ? 111 HIS C CA  1 
ATOM   4098 C C   . HIS C 1 111 ? 123.735 108.527 150.325 1.00 96.90  ? 111 HIS C C   1 
ATOM   4099 O O   . HIS C 1 111 ? 122.662 109.024 149.971 1.00 96.90  ? 111 HIS C O   1 
ATOM   4100 C CB  . HIS C 1 111 ? 123.911 106.701 151.979 1.00 96.90  ? 111 HIS C CB  1 
ATOM   4101 C CG  . HIS C 1 111 ? 122.731 107.226 152.725 1.00 96.90  ? 111 HIS C CG  1 
ATOM   4102 N ND1 . HIS C 1 111 ? 121.489 106.634 152.661 1.00 96.90  ? 111 HIS C ND1 1 
ATOM   4103 C CD2 . HIS C 1 111 ? 122.588 108.321 153.506 1.00 96.90  ? 111 HIS C CD2 1 
ATOM   4104 C CE1 . HIS C 1 111 ? 120.640 107.323 153.399 1.00 96.90  ? 111 HIS C CE1 1 
ATOM   4105 N NE2 . HIS C 1 111 ? 121.281 108.352 153.922 1.00 96.90  ? 111 HIS C NE2 1 
ATOM   4106 N N   . ARG C 1 112 ? 124.813 109.273 150.573 1.00 90.43  ? 112 ARG C N   1 
ATOM   4107 C CA  . ARG C 1 112 ? 124.723 110.716 150.396 1.00 90.43  ? 112 ARG C CA  1 
ATOM   4108 C C   . ARG C 1 112 ? 124.433 111.053 148.949 1.00 90.43  ? 112 ARG C C   1 
ATOM   4109 O O   . ARG C 1 112 ? 123.892 112.121 148.652 1.00 90.43  ? 112 ARG C O   1 
ATOM   4110 C CB  . ARG C 1 112 ? 126.001 111.421 150.847 1.00 90.43  ? 112 ARG C CB  1 
ATOM   4111 C CG  . ARG C 1 112 ? 127.129 111.423 149.836 1.00 90.43  ? 112 ARG C CG  1 
ATOM   4112 C CD  . ARG C 1 112 ? 128.210 112.396 150.241 1.00 90.43  ? 112 ARG C CD  1 
ATOM   4113 N NE  . ARG C 1 112 ? 128.592 112.211 151.634 1.00 90.43  ? 112 ARG C NE  1 
ATOM   4114 C CZ  . ARG C 1 112 ? 129.550 111.390 152.042 1.00 90.43  ? 112 ARG C CZ  1 
ATOM   4115 N NH1 . ARG C 1 112 ? 130.222 110.670 151.161 1.00 90.43  ? 112 ARG C NH1 1 
ATOM   4116 N NH2 . ARG C 1 112 ? 129.829 111.286 153.332 1.00 90.43  ? 112 ARG C NH2 1 
ATOM   4117 N N   . PHE C 1 113 ? 124.776 110.151 148.031 1.00 85.71  ? 113 PHE C N   1 
ATOM   4118 C CA  . PHE C 1 113 ? 124.480 110.470 146.636 1.00 85.71  ? 113 PHE C CA  1 
ATOM   4119 C C   . PHE C 1 113 ? 123.054 110.131 146.216 1.00 85.71  ? 113 PHE C C   1 
ATOM   4120 O O   . PHE C 1 113 ? 122.528 110.773 145.304 1.00 85.71  ? 113 PHE C O   1 
ATOM   4121 C CB  . PHE C 1 113 ? 125.471 109.778 145.708 1.00 85.71  ? 113 PHE C CB  1 
ATOM   4122 C CG  . PHE C 1 113 ? 126.608 110.652 145.302 1.00 85.71  ? 113 PHE C CG  1 
ATOM   4123 C CD1 . PHE C 1 113 ? 126.644 111.215 144.047 1.00 85.71  ? 113 PHE C CD1 1 
ATOM   4124 C CD2 . PHE C 1 113 ? 127.623 110.938 146.187 1.00 85.71  ? 113 PHE C CD2 1 
ATOM   4125 C CE1 . PHE C 1 113 ? 127.680 112.026 143.677 1.00 85.71  ? 113 PHE C CE1 1 
ATOM   4126 C CE2 . PHE C 1 113 ? 128.662 111.752 145.822 1.00 85.71  ? 113 PHE C CE2 1 
ATOM   4127 C CZ  . PHE C 1 113 ? 128.691 112.295 144.566 1.00 85.71  ? 113 PHE C CZ  1 
ATOM   4128 N N   . VAL C 1 114 ? 122.409 109.147 146.841 1.00 83.48  ? 114 VAL C N   1 
ATOM   4129 C CA  . VAL C 1 114 ? 121.155 108.628 146.297 1.00 83.48  ? 114 VAL C CA  1 
ATOM   4130 C C   . VAL C 1 114 ? 120.012 108.701 147.299 1.00 83.48  ? 114 VAL C C   1 
ATOM   4131 O O   . VAL C 1 114 ? 118.973 108.062 147.106 1.00 83.48  ? 114 VAL C O   1 
ATOM   4132 C CB  . VAL C 1 114 ? 121.327 107.180 145.805 1.00 83.48  ? 114 VAL C CB  1 
ATOM   4133 C CG1 . VAL C 1 114 ? 122.539 107.062 144.911 1.00 83.48  ? 114 VAL C CG1 1 
ATOM   4134 C CG2 . VAL C 1 114 ? 121.415 106.220 146.966 1.00 83.48  ? 114 VAL C CG2 1 
ATOM   4135 N N   . ALA C 1 115 ? 120.173 109.478 148.363 1.00 79.39  ? 115 ALA C N   1 
ATOM   4136 C CA  . ALA C 1 115 ? 119.083 109.629 149.320 1.00 79.39  ? 115 ALA C CA  1 
ATOM   4137 C C   . ALA C 1 115 ? 119.180 110.950 150.066 1.00 79.39  ? 115 ALA C C   1 
ATOM   4138 O O   . ALA C 1 115 ? 120.268 111.516 150.193 1.00 79.39  ? 115 ALA C O   1 
ATOM   4139 C CB  . ALA C 1 115 ? 119.077 108.465 150.308 1.00 79.39  ? 115 ALA C CB  1 
ATOM   4140 N N   . VAL C 1 116 ? 118.059 111.453 150.565 1.00 73.81  ? 116 VAL C N   1 
ATOM   4141 C CA  . VAL C 1 116 ? 118.073 112.696 151.326 1.00 73.81  ? 116 VAL C CA  1 
ATOM   4142 C C   . VAL C 1 116 ? 118.773 112.445 152.653 1.00 73.81  ? 116 VAL C C   1 
ATOM   4143 O O   . VAL C 1 116 ? 118.468 111.479 153.361 1.00 73.81  ? 116 VAL C O   1 
ATOM   4144 C CB  . VAL C 1 116 ? 116.651 113.235 151.529 1.00 73.81  ? 116 VAL C CB  1 
ATOM   4145 C CG1 . VAL C 1 116 ? 116.119 113.759 150.231 1.00 73.81  ? 116 VAL C CG1 1 
ATOM   4146 C CG2 . VAL C 1 116 ? 115.749 112.156 152.047 1.00 73.81  ? 116 VAL C CG2 1 
ATOM   4147 N N   . SER C 1 117 ? 119.731 113.299 152.981 1.00 77.07  ? 117 SER C N   1 
ATOM   4148 C CA  . SER C 1 117 ? 120.579 113.076 154.138 1.00 77.07  ? 117 SER C CA  1 
ATOM   4149 C C   . SER C 1 117 ? 120.224 114.093 155.222 1.00 77.07  ? 117 SER C C   1 
ATOM   4150 O O   . SER C 1 117 ? 119.286 114.876 155.067 1.00 77.07  ? 117 SER C O   1 
ATOM   4151 C CB  . SER C 1 117 ? 122.047 113.135 153.714 1.00 77.07  ? 117 SER C CB  1 
ATOM   4152 O OG  . SER C 1 117 ? 122.891 112.666 154.748 1.00 77.07  ? 117 SER C OG  1 
ATOM   4153 N N   . TYR C 1 118 ? 120.957 114.074 156.332 1.00 74.52  ? 118 TYR C N   1 
ATOM   4154 C CA  . TYR C 1 118 ? 120.785 115.001 157.449 1.00 74.52  ? 118 TYR C CA  1 
ATOM   4155 C C   . TYR C 1 118 ? 119.467 114.801 158.175 1.00 74.52  ? 118 TYR C C   1 
ATOM   4156 O O   . TYR C 1 118 ? 118.834 115.770 158.588 1.00 74.52  ? 118 TYR C O   1 
ATOM   4157 C CB  . TYR C 1 118 ? 120.911 116.454 156.995 1.00 74.52  ? 118 TYR C CB  1 
ATOM   4158 C CG  . TYR C 1 118 ? 122.150 116.726 156.197 1.00 74.52  ? 118 TYR C CG  1 
ATOM   4159 C CD1 . TYR C 1 118 ? 123.398 116.682 156.781 1.00 74.52  ? 118 TYR C CD1 1 
ATOM   4160 C CD2 . TYR C 1 118 ? 122.071 117.025 154.858 1.00 74.52  ? 118 TYR C CD2 1 
ATOM   4161 C CE1 . TYR C 1 118 ? 124.528 116.931 156.048 1.00 74.52  ? 118 TYR C CE1 1 
ATOM   4162 C CE2 . TYR C 1 118 ? 123.189 117.278 154.122 1.00 74.52  ? 118 TYR C CE2 1 
ATOM   4163 C CZ  . TYR C 1 118 ? 124.417 117.229 154.717 1.00 74.52  ? 118 TYR C CZ  1 
ATOM   4164 O OH  . TYR C 1 118 ? 125.537 117.483 153.966 1.00 74.52  ? 118 TYR C OH  1 
ATOM   4165 N N   . GLN C 1 119 ? 119.035 113.555 158.349 1.00 79.98  ? 119 GLN C N   1 
ATOM   4166 C CA  . GLN C 1 119 ? 117.856 113.285 159.159 1.00 79.98  ? 119 GLN C CA  1 
ATOM   4167 C C   . GLN C 1 119 ? 118.112 113.667 160.608 1.00 79.98  ? 119 GLN C C   1 
ATOM   4168 O O   . GLN C 1 119 ? 119.112 113.245 161.196 1.00 79.98  ? 119 GLN C O   1 
ATOM   4169 C CB  . GLN C 1 119 ? 117.462 111.816 159.078 1.00 79.98  ? 119 GLN C CB  1 
ATOM   4170 C CG  . GLN C 1 119 ? 116.300 111.461 159.976 1.00 79.98  ? 119 GLN C CG  1 
ATOM   4171 C CD  . GLN C 1 119 ? 115.798 110.057 159.750 1.00 79.98  ? 119 GLN C CD  1 
ATOM   4172 O OE1 . GLN C 1 119 ? 116.532 109.193 159.273 1.00 79.98  ? 119 GLN C OE1 1 
ATOM   4173 N NE2 . GLN C 1 119 ? 114.540 109.816 160.098 1.00 79.98  ? 119 GLN C NE2 1 
ATOM   4174 N N   . ILE C 1 120 ? 117.220 114.461 161.200 1.00 82.88  ? 120 ILE C N   1 
ATOM   4175 C CA  . ILE C 1 120 ? 117.417 114.889 162.577 1.00 82.88  ? 120 ILE C CA  1 
ATOM   4176 C C   . ILE C 1 120 ? 117.038 113.760 163.518 1.00 82.88  ? 120 ILE C C   1 
ATOM   4177 O O   . ILE C 1 120 ? 115.855 113.453 163.709 1.00 82.88  ? 120 ILE C O   1 
ATOM   4178 C CB  . ILE C 1 120 ? 116.609 116.161 162.863 1.00 82.88  ? 120 ILE C CB  1 
ATOM   4179 C CG1 . ILE C 1 120 ? 117.163 117.327 162.052 1.00 82.88  ? 120 ILE C CG1 1 
ATOM   4180 C CG2 . ILE C 1 120 ? 116.638 116.491 164.337 1.00 82.88  ? 120 ILE C CG2 1 
ATOM   4181 C CD1 . ILE C 1 120 ? 118.617 117.596 162.308 1.00 82.88  ? 120 ILE C CD1 1 
ATOM   4182 N N   . GLY C 1 121 ? 118.048 113.137 164.119 1.00 90.55  ? 121 GLY C N   1 
ATOM   4183 C CA  . GLY C 1 121 ? 117.834 112.005 164.997 1.00 90.55  ? 121 GLY C CA  1 
ATOM   4184 C C   . GLY C 1 121 ? 117.181 110.840 164.289 1.00 90.55  ? 121 GLY C C   1 
ATOM   4185 O O   . GLY C 1 121 ? 117.679 110.364 163.265 1.00 90.55  ? 121 GLY C O   1 
ATOM   4186 N N   . ASP C 1 122 ? 116.061 110.368 164.832 1.00 98.87  ? 122 ASP C N   1 
ATOM   4187 C CA  . ASP C 1 122 ? 115.266 109.348 164.164 1.00 98.87  ? 122 ASP C CA  1 
ATOM   4188 C C   . ASP C 1 122 ? 113.860 109.912 164.019 1.00 98.87  ? 122 ASP C C   1 
ATOM   4189 O O   . ASP C 1 122 ? 112.872 109.278 164.396 1.00 98.87  ? 122 ASP C O   1 
ATOM   4190 C CB  . ASP C 1 122 ? 115.287 108.035 164.951 1.00 98.87  ? 122 ASP C CB  1 
ATOM   4191 C CG  . ASP C 1 122 ? 114.708 106.864 164.171 1.00 98.87  ? 122 ASP C CG  1 
ATOM   4192 O OD1 . ASP C 1 122 ? 113.483 106.817 163.942 1.00 98.87  ? 122 ASP C OD1 1 
ATOM   4193 O OD2 . ASP C 1 122 ? 115.495 105.979 163.776 1.00 98.87  ? 122 ASP C OD2 1 
ATOM   4194 N N   . THR C 1 123 ? 113.772 111.136 163.509 1.00 89.40  ? 123 THR C N   1 
ATOM   4195 C CA  . THR C 1 123 ? 112.496 111.821 163.398 1.00 89.40  ? 123 THR C CA  1 
ATOM   4196 C C   . THR C 1 123 ? 112.221 112.082 161.922 1.00 89.40  ? 123 THR C C   1 
ATOM   4197 O O   . THR C 1 123 ? 113.101 111.880 161.080 1.00 89.40  ? 123 THR C O   1 
ATOM   4198 C CB  . THR C 1 123 ? 112.533 113.122 164.209 1.00 89.40  ? 123 THR C CB  1 
ATOM   4199 O OG1 . THR C 1 123 ? 112.999 112.832 165.529 1.00 89.40  ? 123 THR C OG1 1 
ATOM   4200 C CG2 . THR C 1 123 ? 111.149 113.727 164.348 1.00 89.40  ? 123 THR C CG2 1 
ATOM   4201 N N   . ASN C 1 124 ? 111.012 112.523 161.591 1.00 80.61  ? 124 ASN C N   1 
ATOM   4202 C CA  . ASN C 1 124 ? 110.712 112.931 160.230 1.00 80.61  ? 124 ASN C CA  1 
ATOM   4203 C C   . ASN C 1 124 ? 111.021 114.413 160.094 1.00 80.61  ? 124 ASN C C   1 
ATOM   4204 O O   . ASN C 1 124 ? 110.111 115.245 160.043 1.00 80.61  ? 124 ASN C O   1 
ATOM   4205 C CB  . ASN C 1 124 ? 109.255 112.628 159.897 1.00 80.61  ? 124 ASN C CB  1 
ATOM   4206 C CG  . ASN C 1 124 ? 108.885 113.023 158.494 1.00 80.61  ? 124 ASN C CG  1 
ATOM   4207 O OD1 . ASN C 1 124 ? 108.277 114.067 158.271 1.00 80.61  ? 124 ASN C OD1 1 
ATOM   4208 N ND2 . ASN C 1 124 ? 109.242 112.185 157.536 1.00 80.61  ? 124 ASN C ND2 1 
ATOM   4209 N N   . ALA C 1 125 ? 112.308 114.751 160.059 1.00 76.97  ? 125 ALA C N   1 
ATOM   4210 C CA  . ALA C 1 125 ? 112.749 116.135 159.913 1.00 76.97  ? 125 ALA C CA  1 
ATOM   4211 C C   . ALA C 1 125 ? 114.183 116.108 159.420 1.00 76.97  ? 125 ALA C C   1 
ATOM   4212 O O   . ALA C 1 125 ? 115.035 115.475 160.047 1.00 76.97  ? 125 ALA C O   1 
ATOM   4213 C CB  . ALA C 1 125 ? 112.642 116.892 161.229 1.00 76.97  ? 125 ALA C CB  1 
ATOM   4214 N N   . TYR C 1 126 ? 114.452 116.782 158.308 1.00 70.29  ? 126 TYR C N   1 
ATOM   4215 C CA  . TYR C 1 126 ? 115.730 116.683 157.624 1.00 70.29  ? 126 TYR C CA  1 
ATOM   4216 C C   . TYR C 1 126 ? 116.375 118.054 157.506 1.00 70.29  ? 126 TYR C C   1 
ATOM   4217 O O   . TYR C 1 126 ? 115.693 119.041 157.232 1.00 70.29  ? 126 TYR C O   1 
ATOM   4218 C CB  . TYR C 1 126 ? 115.545 116.064 156.244 1.00 70.29  ? 126 TYR C CB  1 
ATOM   4219 C CG  . TYR C 1 126 ? 115.107 114.628 156.290 1.00 70.29  ? 126 TYR C CG  1 
ATOM   4220 C CD1 . TYR C 1 126 ? 116.013 113.602 156.111 1.00 70.29  ? 126 TYR C CD1 1 
ATOM   4221 C CD2 . TYR C 1 126 ? 113.785 114.297 156.499 1.00 70.29  ? 126 TYR C CD2 1 
ATOM   4222 C CE1 . TYR C 1 126 ? 115.619 112.295 156.155 1.00 70.29  ? 126 TYR C CE1 1 
ATOM   4223 C CE2 . TYR C 1 126 ? 113.382 112.990 156.542 1.00 70.29  ? 126 TYR C CE2 1 
ATOM   4224 C CZ  . TYR C 1 126 ? 114.303 111.994 156.371 1.00 70.29  ? 126 TYR C CZ  1 
ATOM   4225 O OH  . TYR C 1 126 ? 113.903 110.684 156.413 1.00 70.29  ? 126 TYR C OH  1 
ATOM   4226 N N   . GLY C 1 127 ? 117.688 118.106 157.703 1.00 69.49  ? 127 GLY C N   1 
ATOM   4227 C CA  . GLY C 1 127 ? 118.421 119.356 157.675 1.00 69.49  ? 127 GLY C CA  1 
ATOM   4228 C C   . GLY C 1 127 ? 118.942 119.729 156.304 1.00 69.49  ? 127 GLY C C   1 
ATOM   4229 O O   . GLY C 1 127 ? 118.402 119.283 155.294 1.00 69.49  ? 127 GLY C O   1 
ATOM   4230 N N   . LYS C 1 128 ? 119.986 120.549 156.252 1.00 65.33  ? 128 LYS C N   1 
ATOM   4231 C CA  . LYS C 1 128 ? 120.545 121.008 154.992 1.00 65.33  ? 128 LYS C CA  1 
ATOM   4232 C C   . LYS C 1 128 ? 122.054 120.845 155.019 1.00 65.33  ? 128 LYS C C   1 
ATOM   4233 O O   . LYS C 1 128 ? 122.667 120.883 156.086 1.00 65.33  ? 128 LYS C O   1 
ATOM   4234 C CB  . LYS C 1 128 ? 120.196 122.472 154.730 1.00 65.33  ? 128 LYS C CB  1 
ATOM   4235 C CG  . LYS C 1 128 ? 118.734 122.813 154.891 1.00 65.33  ? 128 LYS C CG  1 
ATOM   4236 C CD  . LYS C 1 128 ? 118.518 124.289 154.672 1.00 65.33  ? 128 LYS C CD  1 
ATOM   4237 C CE  . LYS C 1 128 ? 117.276 124.776 155.375 1.00 65.33  ? 128 LYS C CE  1 
ATOM   4238 N NZ  . LYS C 1 128 ? 116.043 124.193 154.813 1.00 65.33  ? 128 LYS C NZ  1 
ATOM   4239 N N   . GLY C 1 129 ? 122.649 120.670 153.850 1.00 71.28  ? 129 GLY C N   1 
ATOM   4240 C CA  . GLY C 1 129 ? 124.091 120.562 153.784 1.00 71.28  ? 129 GLY C CA  1 
ATOM   4241 C C   . GLY C 1 129 ? 124.562 120.302 152.373 1.00 71.28  ? 129 GLY C C   1 
ATOM   4242 O O   . GLY C 1 129 ? 123.793 120.378 151.417 1.00 71.28  ? 129 GLY C O   1 
ATOM   4243 N N   . ILE C 1 130 ? 125.854 119.991 152.255 1.00 74.23  ? 130 ILE C N   1 
ATOM   4244 C CA  . ILE C 1 130 ? 126.454 119.702 150.954 1.00 74.23  ? 130 ILE C CA  1 
ATOM   4245 C C   . ILE C 1 130 ? 125.920 118.422 150.328 1.00 74.23  ? 130 ILE C C   1 
ATOM   4246 O O   . ILE C 1 130 ? 125.872 118.307 149.089 1.00 74.23  ? 130 ILE C O   1 
ATOM   4247 C CB  . ILE C 1 130 ? 127.983 119.665 151.125 1.00 74.23  ? 130 ILE C CB  1 
ATOM   4248 C CG1 . ILE C 1 130 ? 128.683 119.623 149.772 1.00 74.23  ? 130 ILE C CG1 1 
ATOM   4249 C CG2 . ILE C 1 130 ? 128.402 118.503 151.999 1.00 74.23  ? 130 ILE C CG2 1 
ATOM   4250 C CD1 . ILE C 1 130 ? 128.596 120.904 149.017 1.00 74.23  ? 130 ILE C CD1 1 
ATOM   4251 N N   . ASN C 1 131 ? 125.499 117.456 151.139 1.00 75.89  ? 131 ASN C N   1 
ATOM   4252 C CA  . ASN C 1 131 ? 124.885 116.264 150.584 1.00 75.89  ? 131 ASN C CA  1 
ATOM   4253 C C   . ASN C 1 131 ? 123.633 116.582 149.783 1.00 75.89  ? 131 ASN C C   1 
ATOM   4254 O O   . ASN C 1 131 ? 123.258 115.798 148.908 1.00 75.89  ? 131 ASN C O   1 
ATOM   4255 C CB  . ASN C 1 131 ? 124.557 115.277 151.696 1.00 75.89  ? 131 ASN C CB  1 
ATOM   4256 C CG  . ASN C 1 131 ? 125.792 114.668 152.299 1.00 75.89  ? 131 ASN C CG  1 
ATOM   4257 O OD1 . ASN C 1 131 ? 126.897 114.871 151.802 1.00 75.89  ? 131 ASN C OD1 1 
ATOM   4258 N ND2 . ASN C 1 131 ? 125.618 113.917 153.377 1.00 75.89  ? 131 ASN C ND2 1 
ATOM   4259 N N   . ASP C 1 132 ? 122.991 117.719 150.049 1.00 71.78  ? 132 ASP C N   1 
ATOM   4260 C CA  . ASP C 1 132 ? 121.906 118.176 149.190 1.00 71.78  ? 132 ASP C CA  1 
ATOM   4261 C C   . ASP C 1 132 ? 122.408 118.465 147.785 1.00 71.78  ? 132 ASP C C   1 
ATOM   4262 O O   . ASP C 1 132 ? 121.744 118.134 146.801 1.00 71.78  ? 132 ASP C O   1 
ATOM   4263 C CB  . ASP C 1 132 ? 121.246 119.411 149.789 1.00 71.78  ? 132 ASP C CB  1 
ATOM   4264 C CG  . ASP C 1 132 ? 120.441 119.092 151.019 1.00 71.78  ? 132 ASP C CG  1 
ATOM   4265 O OD1 . ASP C 1 132 ? 120.700 118.050 151.650 1.00 71.78  ? 132 ASP C OD1 1 
ATOM   4266 O OD2 . ASP C 1 132 ? 119.539 119.884 151.356 1.00 71.78  ? 132 ASP C OD2 1 
ATOM   4267 N N   . LEU C 1 133 ? 123.577 119.093 147.667 1.00 75.47  ? 133 LEU C N   1 
ATOM   4268 C CA  . LEU C 1 133 ? 124.161 119.300 146.348 1.00 75.47  ? 133 LEU C CA  1 
ATOM   4269 C C   . LEU C 1 133 ? 124.486 117.976 145.681 1.00 75.47  ? 133 LEU C C   1 
ATOM   4270 O O   . LEU C 1 133 ? 124.284 117.816 144.471 1.00 75.47  ? 133 LEU C O   1 
ATOM   4271 C CB  . LEU C 1 133 ? 125.412 120.163 146.443 1.00 75.47  ? 133 LEU C CB  1 
ATOM   4272 C CG  . LEU C 1 133 ? 125.134 121.650 146.352 1.00 75.47  ? 133 LEU C CG  1 
ATOM   4273 C CD1 . LEU C 1 133 ? 126.405 122.435 146.533 1.00 75.47  ? 133 LEU C CD1 1 
ATOM   4274 C CD2 . LEU C 1 133 ? 124.540 121.922 144.999 1.00 75.47  ? 133 LEU C CD2 1 
ATOM   4275 N N   . CYS C 1 134 ? 124.991 117.010 146.447 1.00 78.95  ? 134 CYS C N   1 
ATOM   4276 C CA  . CYS C 1 134 ? 125.253 115.705 145.845 1.00 78.95  ? 134 CYS C CA  1 
ATOM   4277 C C   . CYS C 1 134 ? 123.971 115.058 145.331 1.00 78.95  ? 134 CYS C C   1 
ATOM   4278 O O   . CYS C 1 134 ? 123.947 114.510 144.221 1.00 78.95  ? 134 CYS C O   1 
ATOM   4279 C CB  . CYS C 1 134 ? 125.947 114.793 146.847 1.00 78.95  ? 134 CYS C CB  1 
ATOM   4280 S SG  . CYS C 1 134 ? 127.619 115.318 147.266 1.00 78.95  ? 134 CYS C SG  1 
ATOM   4281 N N   . PHE C 1 135 ? 122.900 115.121 146.115 1.00 72.56  ? 135 PHE C N   1 
ATOM   4282 C CA  . PHE C 1 135 ? 121.602 114.601 145.705 1.00 72.56  ? 135 PHE C CA  1 
ATOM   4283 C C   . PHE C 1 135 ? 121.080 115.291 144.455 1.00 72.56  ? 135 PHE C C   1 
ATOM   4284 O O   . PHE C 1 135 ? 120.577 114.625 143.541 1.00 72.56  ? 135 PHE C O   1 
ATOM   4285 C CB  . PHE C 1 135 ? 120.623 114.783 146.859 1.00 72.56  ? 135 PHE C CB  1 
ATOM   4286 C CG  . PHE C 1 135 ? 119.240 114.293 146.586 1.00 72.56  ? 135 PHE C CG  1 
ATOM   4287 C CD1 . PHE C 1 135 ? 118.869 113.018 146.933 1.00 72.56  ? 135 PHE C CD1 1 
ATOM   4288 C CD2 . PHE C 1 135 ? 118.295 115.127 146.028 1.00 72.56  ? 135 PHE C CD2 1 
ATOM   4289 C CE1 . PHE C 1 135 ? 117.594 112.582 146.709 1.00 72.56  ? 135 PHE C CE1 1 
ATOM   4290 C CE2 . PHE C 1 135 ? 117.024 114.687 145.797 1.00 72.56  ? 135 PHE C CE2 1 
ATOM   4291 C CZ  . PHE C 1 135 ? 116.672 113.417 146.138 1.00 72.56  ? 135 PHE C CZ  1 
ATOM   4292 N N   . VAL C 1 136 ? 121.178 116.616 144.404 1.00 73.88  ? 136 VAL C N   1 
ATOM   4293 C CA  . VAL C 1 136 ? 120.699 117.353 143.245 1.00 73.88  ? 136 VAL C CA  1 
ATOM   4294 C C   . VAL C 1 136 ? 121.478 116.955 142.005 1.00 73.88  ? 136 VAL C C   1 
ATOM   4295 O O   . VAL C 1 136 ? 120.899 116.754 140.939 1.00 73.88  ? 136 VAL C O   1 
ATOM   4296 C CB  . VAL C 1 136 ? 120.777 118.866 143.501 1.00 73.88  ? 136 VAL C CB  1 
ATOM   4297 C CG1 . VAL C 1 136 ? 120.588 119.624 142.217 1.00 73.88  ? 136 VAL C CG1 1 
ATOM   4298 C CG2 . VAL C 1 136 ? 119.728 119.268 144.491 1.00 73.88  ? 136 VAL C CG2 1 
ATOM   4299 N N   . PHE C 1 137 ? 122.800 116.824 142.121 1.00 79.37  ? 137 PHE C N   1 
ATOM   4300 C CA  . PHE C 1 137 ? 123.597 116.370 140.985 1.00 79.37  ? 137 PHE C CA  1 
ATOM   4301 C C   . PHE C 1 137 ? 123.158 114.991 140.511 1.00 79.37  ? 137 PHE C C   1 
ATOM   4302 O O   . PHE C 1 137 ? 122.931 114.772 139.308 1.00 79.37  ? 137 PHE C O   1 
ATOM   4303 C CB  . PHE C 1 137 ? 125.071 116.360 141.375 1.00 79.37  ? 137 PHE C CB  1 
ATOM   4304 C CG  . PHE C 1 137 ? 125.962 115.719 140.357 1.00 79.37  ? 137 PHE C CG  1 
ATOM   4305 C CD1 . PHE C 1 137 ? 126.317 116.388 139.203 1.00 79.37  ? 137 PHE C CD1 1 
ATOM   4306 C CD2 . PHE C 1 137 ? 126.453 114.440 140.564 1.00 79.37  ? 137 PHE C CD2 1 
ATOM   4307 C CE1 . PHE C 1 137 ? 127.136 115.795 138.273 1.00 79.37  ? 137 PHE C CE1 1 
ATOM   4308 C CE2 . PHE C 1 137 ? 127.270 113.844 139.638 1.00 79.37  ? 137 PHE C CE2 1 
ATOM   4309 C CZ  . PHE C 1 137 ? 127.614 114.521 138.491 1.00 79.37  ? 137 PHE C CZ  1 
ATOM   4310 N N   . TYR C 1 138 ? 123.019 114.050 141.438 1.00 78.52  ? 138 TYR C N   1 
ATOM   4311 C CA  . TYR C 1 138 ? 122.677 112.703 141.015 1.00 78.52  ? 138 TYR C CA  1 
ATOM   4312 C C   . TYR C 1 138 ? 121.315 112.631 140.355 1.00 78.52  ? 138 TYR C C   1 
ATOM   4313 O O   . TYR C 1 138 ? 121.141 111.899 139.372 1.00 78.52  ? 138 TYR C O   1 
ATOM   4314 C CB  . TYR C 1 138 ? 122.712 111.744 142.181 1.00 78.52  ? 138 TYR C CB  1 
ATOM   4315 C CG  . TYR C 1 138 ? 122.589 110.338 141.708 1.00 78.52  ? 138 TYR C CG  1 
ATOM   4316 C CD1 . TYR C 1 138 ? 123.637 109.729 141.051 1.00 78.52  ? 138 TYR C CD1 1 
ATOM   4317 C CD2 . TYR C 1 138 ? 121.425 109.625 141.891 1.00 78.52  ? 138 TYR C CD2 1 
ATOM   4318 C CE1 . TYR C 1 138 ? 123.535 108.445 140.603 1.00 78.52  ? 138 TYR C CE1 1 
ATOM   4319 C CE2 . TYR C 1 138 ? 121.313 108.339 141.449 1.00 78.52  ? 138 TYR C CE2 1 
ATOM   4320 C CZ  . TYR C 1 138 ? 122.372 107.754 140.806 1.00 78.52  ? 138 TYR C CZ  1 
ATOM   4321 O OH  . TYR C 1 138 ? 122.281 106.469 140.354 1.00 78.52  ? 138 TYR C OH  1 
ATOM   4322 N N   . TYR C 1 139 ? 120.342 113.374 140.845 1.00 75.04  ? 139 TYR C N   1 
ATOM   4323 C CA  . TYR C 1 139 ? 119.060 113.294 140.174 1.00 75.04  ? 139 TYR C CA  1 
ATOM   4324 C C   . TYR C 1 139 ? 118.943 114.241 138.989 1.00 75.04  ? 139 TYR C C   1 
ATOM   4325 O O   . TYR C 1 139 ? 118.024 114.080 138.191 1.00 75.04  ? 139 TYR C O   1 
ATOM   4326 C CB  . TYR C 1 139 ? 117.944 113.494 141.180 1.00 75.04  ? 139 TYR C CB  1 
ATOM   4327 C CG  . TYR C 1 139 ? 117.746 112.223 141.951 1.00 75.04  ? 139 TYR C CG  1 
ATOM   4328 C CD1 . TYR C 1 139 ? 117.128 111.137 141.373 1.00 75.04  ? 139 TYR C CD1 1 
ATOM   4329 C CD2 . TYR C 1 139 ? 118.243 112.085 143.226 1.00 75.04  ? 139 TYR C CD2 1 
ATOM   4330 C CE1 . TYR C 1 139 ? 116.967 109.966 142.062 1.00 75.04  ? 139 TYR C CE1 1 
ATOM   4331 C CE2 . TYR C 1 139 ? 118.092 110.918 143.922 1.00 75.04  ? 139 TYR C CE2 1 
ATOM   4332 C CZ  . TYR C 1 139 ? 117.451 109.865 143.338 1.00 75.04  ? 139 TYR C CZ  1 
ATOM   4333 O OH  . TYR C 1 139 ? 117.301 108.700 144.042 1.00 75.04  ? 139 TYR C OH  1 
ATOM   4334 N N   . MET C 1 140 ? 119.883 115.164 138.798 1.00 78.71  ? 140 MET C N   1 
ATOM   4335 C CA  . MET C 1 140 ? 120.062 115.726 137.466 1.00 78.71  ? 140 MET C CA  1 
ATOM   4336 C C   . MET C 1 140 ? 120.412 114.630 136.480 1.00 78.71  ? 140 MET C C   1 
ATOM   4337 O O   . MET C 1 140 ? 119.858 114.571 135.377 1.00 78.71  ? 140 MET C O   1 
ATOM   4338 C CB  . MET C 1 140 ? 121.156 116.791 137.459 1.00 78.71  ? 140 MET C CB  1 
ATOM   4339 C CG  . MET C 1 140 ? 120.845 118.041 138.224 1.00 78.71  ? 140 MET C CG  1 
ATOM   4340 S SD  . MET C 1 140 ? 122.240 119.173 138.212 1.00 78.71  ? 140 MET C SD  1 
ATOM   4341 C CE  . MET C 1 140 ? 122.220 119.694 136.509 1.00 78.71  ? 140 MET C CE  1 
ATOM   4342 N N   . ILE C 1 141 ? 121.332 113.745 136.862 1.00 78.41  ? 141 ILE C N   1 
ATOM   4343 C CA  . ILE C 1 141 ? 121.671 112.628 135.976 1.00 78.41  ? 141 ILE C CA  1 
ATOM   4344 C C   . ILE C 1 141 ? 120.440 111.765 135.723 1.00 78.41  ? 141 ILE C C   1 
ATOM   4345 O O   . ILE C 1 141 ? 120.146 111.371 134.584 1.00 78.41  ? 141 ILE C O   1 
ATOM   4346 C CB  . ILE C 1 141 ? 122.826 111.803 136.565 1.00 78.41  ? 141 ILE C CB  1 
ATOM   4347 C CG1 . ILE C 1 141 ? 123.979 112.719 136.953 1.00 78.41  ? 141 ILE C CG1 1 
ATOM   4348 C CG2 . ILE C 1 141 ? 123.308 110.786 135.566 1.00 78.41  ? 141 ILE C CG2 1 
ATOM   4349 C CD1 . ILE C 1 141 ? 124.518 113.514 135.800 1.00 78.41  ? 141 ILE C CD1 1 
ATOM   4350 N N   . PHE C 1 142 ? 119.695 111.469 136.787 1.00 80.40  ? 142 PHE C N   1 
ATOM   4351 C CA  . PHE C 1 142 ? 118.465 110.697 136.631 1.00 80.40  ? 142 PHE C CA  1 
ATOM   4352 C C   . PHE C 1 142 ? 117.479 111.354 135.675 1.00 80.40  ? 142 PHE C C   1 
ATOM   4353 O O   . PHE C 1 142 ? 116.940 110.680 134.795 1.00 80.40  ? 142 PHE C O   1 
ATOM   4354 C CB  . PHE C 1 142 ? 117.774 110.492 137.971 1.00 80.40  ? 142 PHE C CB  1 
ATOM   4355 C CG  . PHE C 1 142 ? 116.398 109.911 137.853 1.00 80.40  ? 142 PHE C CG  1 
ATOM   4356 C CD1 . PHE C 1 142 ? 116.217 108.571 137.626 1.00 80.40  ? 142 PHE C CD1 1 
ATOM   4357 C CD2 . PHE C 1 142 ? 115.286 110.718 137.955 1.00 80.40  ? 142 PHE C CD2 1 
ATOM   4358 C CE1 . PHE C 1 142 ? 114.958 108.042 137.513 1.00 80.40  ? 142 PHE C CE1 1 
ATOM   4359 C CE2 . PHE C 1 142 ? 114.023 110.196 137.840 1.00 80.40  ? 142 PHE C CE2 1 
ATOM   4360 C CZ  . PHE C 1 142 ? 113.857 108.857 137.619 1.00 80.40  ? 142 PHE C CZ  1 
ATOM   4361 N N   . PHE C 1 143 ? 117.197 112.644 135.850 1.00 79.46  ? 143 PHE C N   1 
ATOM   4362 C CA  . PHE C 1 143 ? 116.208 113.296 135.006 1.00 79.46  ? 143 PHE C CA  1 
ATOM   4363 C C   . PHE C 1 143 ? 116.687 113.423 133.573 1.00 79.46  ? 143 PHE C C   1 
ATOM   4364 O O   . PHE C 1 143 ? 115.867 113.390 132.654 1.00 79.46  ? 143 PHE C O   1 
ATOM   4365 C CB  . PHE C 1 143 ? 115.848 114.667 135.564 1.00 79.46  ? 143 PHE C CB  1 
ATOM   4366 C CG  . PHE C 1 143 ? 114.874 114.615 136.699 1.00 79.46  ? 143 PHE C CG  1 
ATOM   4367 C CD1 . PHE C 1 143 ? 113.615 114.097 136.516 1.00 79.46  ? 143 PHE C CD1 1 
ATOM   4368 C CD2 . PHE C 1 143 ? 115.216 115.086 137.945 1.00 79.46  ? 143 PHE C CD2 1 
ATOM   4369 C CE1 . PHE C 1 143 ? 112.725 114.046 137.555 1.00 79.46  ? 143 PHE C CE1 1 
ATOM   4370 C CE2 . PHE C 1 143 ? 114.332 115.034 138.980 1.00 79.46  ? 143 PHE C CE2 1 
ATOM   4371 C CZ  . PHE C 1 143 ? 113.089 114.517 138.786 1.00 79.46  ? 143 PHE C CZ  1 
ATOM   4372 N N   . THR C 1 144 ? 117.996 113.562 133.355 1.00 85.38  ? 144 THR C N   1 
ATOM   4373 C CA  . THR C 1 144 ? 118.517 113.482 131.998 1.00 85.38  ? 144 THR C CA  1 
ATOM   4374 C C   . THR C 1 144 ? 118.257 112.128 131.369 1.00 85.38  ? 144 THR C C   1 
ATOM   4375 O O   . THR C 1 144 ? 117.887 112.070 130.193 1.00 85.38  ? 144 THR C O   1 
ATOM   4376 C CB  . THR C 1 144 ? 120.012 113.782 131.972 1.00 85.38  ? 144 THR C CB  1 
ATOM   4377 O OG1 . THR C 1 144 ? 120.239 115.109 132.451 1.00 85.38  ? 144 THR C OG1 1 
ATOM   4378 C CG2 . THR C 1 144 ? 120.545 113.677 130.563 1.00 85.38  ? 144 THR C CG2 1 
ATOM   4379 N N   . PHE C 1 145 ? 118.433 111.040 132.114 1.00 91.21  ? 145 PHE C N   1 
ATOM   4380 C CA  . PHE C 1 145 ? 117.987 109.759 131.578 1.00 91.21  ? 145 PHE C CA  1 
ATOM   4381 C C   . PHE C 1 145 ? 116.499 109.739 131.281 1.00 91.21  ? 145 PHE C C   1 
ATOM   4382 O O   . PHE C 1 145 ? 116.093 109.313 130.191 1.00 91.21  ? 145 PHE C O   1 
ATOM   4383 C CB  . PHE C 1 145 ? 118.286 108.616 132.544 1.00 91.21  ? 145 PHE C CB  1 
ATOM   4384 C CG  . PHE C 1 145 ? 117.302 107.485 132.454 1.00 91.21  ? 145 PHE C CG  1 
ATOM   4385 C CD1 . PHE C 1 145 ? 117.334 106.603 131.401 1.00 91.21  ? 145 PHE C CD1 1 
ATOM   4386 C CD2 . PHE C 1 145 ? 116.334 107.317 133.422 1.00 91.21  ? 145 PHE C CD2 1 
ATOM   4387 C CE1 . PHE C 1 145 ? 116.426 105.576 131.320 1.00 91.21  ? 145 PHE C CE1 1 
ATOM   4388 C CE2 . PHE C 1 145 ? 115.425 106.292 133.342 1.00 91.21  ? 145 PHE C CE2 1 
ATOM   4389 C CZ  . PHE C 1 145 ? 115.470 105.422 132.291 1.00 91.21  ? 145 PHE C CZ  1 
ATOM   4390 N N   . LEU C 1 146 ? 115.687 110.176 132.239 1.00 92.55  ? 146 LEU C N   1 
ATOM   4391 C CA  . LEU C 1 146 ? 114.246 110.012 132.125 1.00 92.55  ? 146 LEU C CA  1 
ATOM   4392 C C   . LEU C 1 146 ? 113.692 110.802 130.956 1.00 92.55  ? 146 LEU C C   1 
ATOM   4393 O O   . LEU C 1 146 ? 112.826 110.310 130.228 1.00 92.55  ? 146 LEU C O   1 
ATOM   4394 C CB  . LEU C 1 146 ? 113.560 110.436 133.418 1.00 92.55  ? 146 LEU C CB  1 
ATOM   4395 C CG  . LEU C 1 146 ? 112.048 110.245 133.419 1.00 92.55  ? 146 LEU C CG  1 
ATOM   4396 C CD1 . LEU C 1 146 ? 111.697 108.785 133.266 1.00 92.55  ? 146 LEU C CD1 1 
ATOM   4397 C CD2 . LEU C 1 146 ? 111.466 110.798 134.691 1.00 92.55  ? 146 LEU C CD2 1 
ATOM   4398 N N   . ARG C 1 147 ? 114.175 112.026 130.756 1.00 98.72  ? 147 ARG C N   1 
ATOM   4399 C CA  . ARG C 1 147 ? 113.663 112.845 129.666 1.00 98.72  ? 147 ARG C CA  1 
ATOM   4400 C C   . ARG C 1 147 ? 113.829 112.136 128.336 1.00 98.72  ? 147 ARG C C   1 
ATOM   4401 O O   . ARG C 1 147 ? 112.859 111.946 127.601 1.00 98.72  ? 147 ARG C O   1 
ATOM   4402 C CB  . ARG C 1 147 ? 114.370 114.193 129.641 1.00 98.72  ? 147 ARG C CB  1 
ATOM   4403 C CG  . ARG C 1 147 ? 113.896 115.074 128.523 1.00 98.72  ? 147 ARG C CG  1 
ATOM   4404 C CD  . ARG C 1 147 ? 114.400 116.486 128.676 1.00 98.72  ? 147 ARG C CD  1 
ATOM   4405 N NE  . ARG C 1 147 ? 114.014 117.305 127.533 1.00 98.72  ? 147 ARG C NE  1 
ATOM   4406 C CZ  . ARG C 1 147 ? 114.591 117.244 126.337 1.00 98.72  ? 147 ARG C CZ  1 
ATOM   4407 N NH1 . ARG C 1 147 ? 114.168 118.027 125.355 1.00 98.72  ? 147 ARG C NH1 1 
ATOM   4408 N NH2 . ARG C 1 147 ? 115.594 116.404 126.122 1.00 98.72  ? 147 ARG C NH2 1 
ATOM   4409 N N   . GLU C 1 148 ? 115.045 111.690 128.028 1.00 105.22 ? 148 GLU C N   1 
ATOM   4410 C CA  . GLU C 1 148 ? 115.294 111.043 126.745 1.00 105.22 ? 148 GLU C CA  1 
ATOM   4411 C C   . GLU C 1 148 ? 114.530 109.731 126.624 1.00 105.22 ? 148 GLU C C   1 
ATOM   4412 O O   . GLU C 1 148 ? 113.876 109.466 125.605 1.00 105.22 ? 148 GLU C O   1 
ATOM   4413 C CB  . GLU C 1 148 ? 116.794 110.816 126.558 1.00 105.22 ? 148 GLU C CB  1 
ATOM   4414 C CG  . GLU C 1 148 ? 117.660 111.973 127.019 1.00 105.22 ? 148 GLU C CG  1 
ATOM   4415 C CD  . GLU C 1 148 ? 117.662 113.136 126.046 1.00 105.22 ? 148 GLU C CD  1 
ATOM   4416 O OE1 . GLU C 1 148 ? 117.007 113.040 124.989 1.00 105.22 ? 148 GLU C OE1 1 
ATOM   4417 O OE2 . GLU C 1 148 ? 118.327 114.150 126.338 1.00 105.22 ? 148 GLU C OE2 1 
ATOM   4418 N N   . PHE C 1 149 ? 114.607 108.890 127.658 1.00 104.86 ? 149 PHE C N   1 
ATOM   4419 C CA  . PHE C 1 149 ? 113.976 107.579 127.563 1.00 104.86 ? 149 PHE C CA  1 
ATOM   4420 C C   . PHE C 1 149 ? 112.473 107.701 127.396 1.00 104.86 ? 149 PHE C C   1 
ATOM   4421 O O   . PHE C 1 149 ? 111.888 107.119 126.471 1.00 104.86 ? 149 PHE C O   1 
ATOM   4422 C CB  . PHE C 1 149 ? 114.297 106.751 128.800 1.00 104.86 ? 149 PHE C CB  1 
ATOM   4423 C CG  . PHE C 1 149 ? 113.496 105.495 128.904 1.00 104.86 ? 149 PHE C CG  1 
ATOM   4424 C CD1 . PHE C 1 149 ? 113.950 104.329 128.333 1.00 104.86 ? 149 PHE C CD1 1 
ATOM   4425 C CD2 . PHE C 1 149 ? 112.288 105.481 129.574 1.00 104.86 ? 149 PHE C CD2 1 
ATOM   4426 C CE1 . PHE C 1 149 ? 113.218 103.177 128.423 1.00 104.86 ? 149 PHE C CE1 1 
ATOM   4427 C CE2 . PHE C 1 149 ? 111.550 104.332 129.663 1.00 104.86 ? 149 PHE C CE2 1 
ATOM   4428 C CZ  . PHE C 1 149 ? 112.016 103.177 129.089 1.00 104.86 ? 149 PHE C CZ  1 
ATOM   4429 N N   . LEU C 1 150 ? 111.822 108.437 128.290 1.00 108.93 ? 150 LEU C N   1 
ATOM   4430 C CA  . LEU C 1 150 ? 110.396 108.644 128.139 1.00 108.93 ? 150 LEU C CA  1 
ATOM   4431 C C   . LEU C 1 150 ? 110.101 109.258 126.787 1.00 108.93 ? 150 LEU C C   1 
ATOM   4432 O O   . LEU C 1 150 ? 109.326 108.695 126.010 1.00 108.93 ? 150 LEU C O   1 
ATOM   4433 C CB  . LEU C 1 150 ? 109.869 109.525 129.262 1.00 108.93 ? 150 LEU C CB  1 
ATOM   4434 C CG  . LEU C 1 150 ? 108.372 109.750 129.136 1.00 108.93 ? 150 LEU C CG  1 
ATOM   4435 C CD1 . LEU C 1 150 ? 107.627 108.527 129.627 1.00 108.93 ? 150 LEU C CD1 1 
ATOM   4436 C CD2 . LEU C 1 150 ? 107.958 110.979 129.908 1.00 108.93 ? 150 LEU C CD2 1 
ATOM   4437 N N   . MET C 1 151 ? 110.789 110.359 126.456 1.00 115.21 ? 151 MET C N   1 
ATOM   4438 C CA  . MET C 1 151 ? 110.557 111.075 125.211 1.00 115.21 ? 151 MET C CA  1 
ATOM   4439 C C   . MET C 1 151 ? 110.448 110.111 124.047 1.00 115.21 ? 151 MET C C   1 
ATOM   4440 O O   . MET C 1 151 ? 109.343 109.841 123.561 1.00 115.21 ? 151 MET C O   1 
ATOM   4441 C CB  . MET C 1 151 ? 111.703 112.061 124.980 1.00 115.21 ? 151 MET C CB  1 
ATOM   4442 C CG  . MET C 1 151 ? 111.525 112.952 123.786 1.00 115.21 ? 151 MET C CG  1 
ATOM   4443 S SD  . MET C 1 151 ? 110.106 114.035 123.975 1.00 115.21 ? 151 MET C SD  1 
ATOM   4444 C CE  . MET C 1 151 ? 110.734 115.179 125.199 1.00 115.21 ? 151 MET C CE  1 
ATOM   4445 N N   . ASP C 1 152 ? 111.556 109.449 123.699 1.00 114.84 ? 152 ASP C N   1 
ATOM   4446 C CA  . ASP C 1 152 ? 111.485 108.593 122.522 1.00 114.84 ? 152 ASP C CA  1 
ATOM   4447 C C   . ASP C 1 152 ? 110.513 107.445 122.768 1.00 114.84 ? 152 ASP C C   1 
ATOM   4448 O O   . ASP C 1 152 ? 109.404 107.445 122.225 1.00 114.84 ? 152 ASP C O   1 
ATOM   4449 C CB  . ASP C 1 152 ? 112.869 108.086 122.084 1.00 114.84 ? 152 ASP C CB  1 
ATOM   4450 C CG  . ASP C 1 152 ? 113.547 107.208 123.107 1.00 114.84 ? 152 ASP C CG  1 
ATOM   4451 O OD1 . ASP C 1 152 ? 112.986 107.006 124.190 1.00 114.84 ? 152 ASP C OD1 1 
ATOM   4452 O OD2 . ASP C 1 152 ? 114.641 106.686 122.809 1.00 114.84 ? 152 ASP C OD2 1 
ATOM   4453 N N   . VAL C 1 153 ? 110.851 106.546 123.697 1.00 114.26 ? 153 VAL C N   1 
ATOM   4454 C CA  . VAL C 1 153 ? 110.234 105.226 123.705 1.00 114.26 ? 153 VAL C CA  1 
ATOM   4455 C C   . VAL C 1 153 ? 108.740 105.313 123.981 1.00 114.26 ? 153 VAL C C   1 
ATOM   4456 O O   . VAL C 1 153 ? 107.950 104.546 123.420 1.00 114.26 ? 153 VAL C O   1 
ATOM   4457 C CB  . VAL C 1 153 ? 110.949 104.312 124.712 1.00 114.26 ? 153 VAL C CB  1 
ATOM   4458 C CG1 . VAL C 1 153 ? 110.110 103.088 125.006 1.00 114.26 ? 153 VAL C CG1 1 
ATOM   4459 C CG2 . VAL C 1 153 ? 112.296 103.905 124.159 1.00 114.26 ? 153 VAL C CG2 1 
ATOM   4460 N N   . VAL C 1 154 ? 108.308 106.237 124.841 1.00 117.09 ? 154 VAL C N   1 
ATOM   4461 C CA  . VAL C 1 154 ? 106.877 106.328 125.065 1.00 117.09 ? 154 VAL C CA  1 
ATOM   4462 C C   . VAL C 1 154 ? 106.223 107.309 124.104 1.00 117.09 ? 154 VAL C C   1 
ATOM   4463 O O   . VAL C 1 154 ? 105.256 106.949 123.426 1.00 117.09 ? 154 VAL C O   1 
ATOM   4464 C CB  . VAL C 1 154 ? 106.575 106.694 126.522 1.00 117.09 ? 154 VAL C CB  1 
ATOM   4465 C CG1 . VAL C 1 154 ? 105.086 106.887 126.703 1.00 117.09 ? 154 VAL C CG1 1 
ATOM   4466 C CG2 . VAL C 1 154 ? 107.067 105.600 127.440 1.00 117.09 ? 154 VAL C CG2 1 
ATOM   4467 N N   . ILE C 1 155 ? 106.692 108.557 124.027 1.00 119.31 ? 155 ILE C N   1 
ATOM   4468 C CA  . ILE C 1 155 ? 105.881 109.503 123.283 1.00 119.31 ? 155 ILE C CA  1 
ATOM   4469 C C   . ILE C 1 155 ? 105.927 109.232 121.786 1.00 119.31 ? 155 ILE C C   1 
ATOM   4470 O O   . ILE C 1 155 ? 104.873 109.191 121.144 1.00 119.31 ? 155 ILE C O   1 
ATOM   4471 C CB  . ILE C 1 155 ? 106.276 110.953 123.591 1.00 119.31 ? 155 ILE C CB  1 
ATOM   4472 C CG1 . ILE C 1 155 ? 105.999 111.292 125.055 1.00 119.31 ? 155 ILE C CG1 1 
ATOM   4473 C CG2 . ILE C 1 155 ? 105.482 111.880 122.711 1.00 119.31 ? 155 ILE C CG2 1 
ATOM   4474 C CD1 . ILE C 1 155 ? 107.122 111.012 125.992 1.00 119.31 ? 155 ILE C CD1 1 
ATOM   4475 N N   . ARG C 1 156 ? 107.114 109.028 121.193 1.00 122.65 ? 156 ARG C N   1 
ATOM   4476 C CA  . ARG C 1 156 ? 107.123 108.967 119.734 1.00 122.65 ? 156 ARG C CA  1 
ATOM   4477 C C   . ARG C 1 156 ? 106.262 107.824 119.200 1.00 122.65 ? 156 ARG C C   1 
ATOM   4478 O O   . ARG C 1 156 ? 105.460 108.057 118.289 1.00 122.65 ? 156 ARG C O   1 
ATOM   4479 C CB  . ARG C 1 156 ? 108.548 108.865 119.189 1.00 122.65 ? 156 ARG C CB  1 
ATOM   4480 C CG  . ARG C 1 156 ? 109.277 110.189 119.092 1.00 122.65 ? 156 ARG C CG  1 
ATOM   4481 C CD  . ARG C 1 156 ? 110.649 109.979 118.489 1.00 122.65 ? 156 ARG C CD  1 
ATOM   4482 N NE  . ARG C 1 156 ? 111.381 111.226 118.307 1.00 122.65 ? 156 ARG C NE  1 
ATOM   4483 C CZ  . ARG C 1 156 ? 111.367 111.937 117.185 1.00 122.65 ? 156 ARG C CZ  1 
ATOM   4484 N NH1 . ARG C 1 156 ? 112.066 113.059 117.097 1.00 122.65 ? 156 ARG C NH1 1 
ATOM   4485 N NH2 . ARG C 1 156 ? 110.652 111.526 116.149 1.00 122.65 ? 156 ARG C NH2 1 
ATOM   4486 N N   . PRO C 1 157 ? 106.368 106.596 119.723 1.00 123.62 ? 157 PRO C N   1 
ATOM   4487 C CA  . PRO C 1 157 ? 105.399 105.573 119.310 1.00 123.62 ? 157 PRO C CA  1 
ATOM   4488 C C   . PRO C 1 157 ? 103.965 105.981 119.568 1.00 123.62 ? 157 PRO C C   1 
ATOM   4489 O O   . PRO C 1 157 ? 103.098 105.715 118.731 1.00 123.62 ? 157 PRO C O   1 
ATOM   4490 C CB  . PRO C 1 157 ? 105.805 104.353 120.145 1.00 123.62 ? 157 PRO C CB  1 
ATOM   4491 C CG  . PRO C 1 157 ? 107.240 104.529 120.348 1.00 123.62 ? 157 PRO C CG  1 
ATOM   4492 C CD  . PRO C 1 157 ? 107.421 106.000 120.562 1.00 123.62 ? 157 PRO C CD  1 
ATOM   4493 N N   . PHE C 1 158 ? 103.686 106.639 120.692 1.00 122.91 ? 158 PHE C N   1 
ATOM   4494 C CA  . PHE C 1 158 ? 102.341 107.145 120.929 1.00 122.91 ? 158 PHE C CA  1 
ATOM   4495 C C   . PHE C 1 158 ? 102.022 108.303 119.996 1.00 122.91 ? 158 PHE C C   1 
ATOM   4496 O O   . PHE C 1 158 ? 100.909 108.403 119.471 1.00 122.91 ? 158 PHE C O   1 
ATOM   4497 C CB  . PHE C 1 158 ? 102.196 107.566 122.392 1.00 122.91 ? 158 PHE C CB  1 
ATOM   4498 C CG  . PHE C 1 158 ? 100.965 108.379 122.678 1.00 122.91 ? 158 PHE C CG  1 
ATOM   4499 C CD1 . PHE C 1 158 ? 99.763  107.762 122.974 1.00 122.91 ? 158 PHE C CD1 1 
ATOM   4500 C CD2 . PHE C 1 158 ? 101.017 109.763 122.685 1.00 122.91 ? 158 PHE C CD2 1 
ATOM   4501 C CE1 . PHE C 1 158 ? 98.633  108.508 123.246 1.00 122.91 ? 158 PHE C CE1 1 
ATOM   4502 C CE2 . PHE C 1 158 ? 99.891  110.510 122.956 1.00 122.91 ? 158 PHE C CE2 1 
ATOM   4503 C CZ  . PHE C 1 158 ? 98.699  109.883 123.235 1.00 122.91 ? 158 PHE C CZ  1 
ATOM   4504 N N   . ALA C 1 159 ? 102.994 109.185 119.766 1.00 126.49 ? 159 ALA C N   1 
ATOM   4505 C CA  . ALA C 1 159 ? 102.716 110.412 119.035 1.00 126.49 ? 159 ALA C CA  1 
ATOM   4506 C C   . ALA C 1 159 ? 102.612 110.191 117.535 1.00 126.49 ? 159 ALA C C   1 
ATOM   4507 O O   . ALA C 1 159 ? 102.171 111.096 116.819 1.00 126.49 ? 159 ALA C O   1 
ATOM   4508 C CB  . ALA C 1 159 ? 103.789 111.456 119.335 1.00 126.49 ? 159 ALA C CB  1 
ATOM   4509 N N   . ILE C 1 160 ? 103.025 109.030 117.033 1.00 130.26 ? 160 ILE C N   1 
ATOM   4510 C CA  . ILE C 1 160 ? 102.819 108.717 115.622 1.00 130.26 ? 160 ILE C CA  1 
ATOM   4511 C C   . ILE C 1 160 ? 102.026 107.423 115.512 1.00 130.26 ? 160 ILE C C   1 
ATOM   4512 O O   . ILE C 1 160 ? 101.835 106.890 114.415 1.00 130.26 ? 160 ILE C O   1 
ATOM   4513 C CB  . ILE C 1 160 ? 104.149 108.610 114.856 1.00 130.26 ? 160 ILE C CB  1 
ATOM   4514 C CG1 . ILE C 1 160 ? 104.937 107.384 115.309 1.00 130.26 ? 160 ILE C CG1 1 
ATOM   4515 C CG2 . ILE C 1 160 ? 104.975 109.867 115.046 1.00 130.26 ? 160 ILE C CG2 1 
ATOM   4516 C CD1 . ILE C 1 160 ? 106.170 107.125 114.488 1.00 130.26 ? 160 ILE C CD1 1 
ATOM   4517 N N   . ARG C 1 161 ? 101.557 106.911 116.647 1.00 133.03 ? 161 ARG C N   1 
ATOM   4518 C CA  . ARG C 1 161 ? 100.790 105.676 116.655 1.00 133.03 ? 161 ARG C CA  1 
ATOM   4519 C C   . ARG C 1 161 ? 99.374  105.877 116.144 1.00 133.03 ? 161 ARG C C   1 
ATOM   4520 O O   . ARG C 1 161 ? 98.712  104.894 115.794 1.00 133.03 ? 161 ARG C O   1 
ATOM   4521 C CB  . ARG C 1 161 ? 100.758 105.086 118.067 1.00 133.03 ? 161 ARG C CB  1 
ATOM   4522 C CG  . ARG C 1 161 ? 100.265 103.649 118.152 1.00 133.03 ? 161 ARG C CG  1 
ATOM   4523 C CD  . ARG C 1 161 ? 101.302 102.687 117.593 1.00 133.03 ? 161 ARG C CD  1 
ATOM   4524 N NE  . ARG C 1 161 ? 100.811 101.314 117.536 1.00 133.03 ? 161 ARG C NE  1 
ATOM   4525 C CZ  . ARG C 1 161 ? 100.104 100.815 116.529 1.00 133.03 ? 161 ARG C CZ  1 
ATOM   4526 N NH1 . ARG C 1 161 ? 99.700  99.554  116.562 1.00 133.03 ? 161 ARG C NH1 1 
ATOM   4527 N NH2 . ARG C 1 161 ? 99.800  101.576 115.486 1.00 133.03 ? 161 ARG C NH2 1 
ATOM   4528 N N   . LEU C 1 162 ? 98.964  107.139 116.158 1.00 138.89 ? 162 LEU C N   1 
ATOM   4529 C CA  . LEU C 1 162 ? 97.684  107.600 115.675 1.00 138.89 ? 162 LEU C CA  1 
ATOM   4530 C C   . LEU C 1 162 ? 98.082  108.592 114.597 1.00 138.89 ? 162 LEU C C   1 
ATOM   4531 O O   . LEU C 1 162 ? 97.328  108.847 113.658 1.00 138.89 ? 162 LEU C O   1 
ATOM   4532 C CB  . LEU C 1 162 ? 96.902  108.298 116.785 1.00 138.89 ? 162 LEU C CB  1 
ATOM   4533 C CG  . LEU C 1 162 ? 97.687  108.643 118.052 1.00 138.89 ? 162 LEU C CG  1 
ATOM   4534 C CD1 . LEU C 1 162 ? 98.636  109.804 117.798 1.00 138.89 ? 162 LEU C CD1 1 
ATOM   4535 C CD2 . LEU C 1 162 ? 96.741  108.959 119.201 1.00 138.89 ? 162 LEU C CD2 1 
ATOM   4536 N N   . HIS C 1 163 ? 99.285  109.152 114.741 1.00 142.51 ? 163 HIS C N   1 
ATOM   4537 C CA  . HIS C 1 163 ? 99.795  110.090 113.738 1.00 142.51 ? 163 HIS C CA  1 
ATOM   4538 C C   . HIS C 1 163 ? 99.471  111.542 113.848 1.00 142.51 ? 163 HIS C C   1 
ATOM   4539 O O   . HIS C 1 163 ? 98.407  111.936 114.230 1.00 142.51 ? 163 HIS C O   1 
ATOM   4540 C CB  . HIS C 1 163 ? 99.477  109.649 112.316 1.00 142.51 ? 163 HIS C CB  1 
ATOM   4541 C CG  . HIS C 1 163 ? 98.534  110.570 111.594 1.00 142.51 ? 163 HIS C CG  1 
ATOM   4542 N ND1 . HIS C 1 163 ? 98.965  111.674 110.889 1.00 142.51 ? 163 HIS C ND1 1 
ATOM   4543 C CD2 . HIS C 1 163 ? 97.188  110.544 111.451 1.00 142.51 ? 163 HIS C CD2 1 
ATOM   4544 C CE1 . HIS C 1 163 ? 97.924  112.288 110.356 1.00 142.51 ? 163 HIS C CE1 1 
ATOM   4545 N NE2 . HIS C 1 163 ? 96.833  111.625 110.682 1.00 142.51 ? 163 HIS C NE2 1 
ATOM   4546 N N   . VAL C 1 164 ? 100.476 112.336 113.514 1.00 138.53 ? 164 VAL C N   1 
ATOM   4547 C CA  . VAL C 1 164 ? 100.441 113.794 113.381 1.00 138.53 ? 164 VAL C CA  1 
ATOM   4548 C C   . VAL C 1 164 ? 101.524 114.110 112.374 1.00 138.53 ? 164 VAL C C   1 
ATOM   4549 O O   . VAL C 1 164 ? 102.582 114.652 112.692 1.00 138.53 ? 164 VAL C O   1 
ATOM   4550 C CB  . VAL C 1 164 ? 100.799 114.589 114.613 1.00 138.53 ? 164 VAL C CB  1 
ATOM   4551 C CG1 . VAL C 1 164 ? 99.813  115.716 114.785 1.00 138.53 ? 164 VAL C CG1 1 
ATOM   4552 C CG2 . VAL C 1 164 ? 101.063 113.739 115.839 1.00 138.53 ? 164 VAL C CG2 1 
ATOM   4553 N N   . THR C 1 165 ? 101.262 113.735 111.145 1.00 142.33 ? 165 THR C N   1 
ATOM   4554 C CA  . THR C 1 165 ? 102.212 113.934 110.072 1.00 142.33 ? 165 THR C CA  1 
ATOM   4555 C C   . THR C 1 165 ? 102.635 115.393 109.777 1.00 142.33 ? 165 THR C C   1 
ATOM   4556 O O   . THR C 1 165 ? 101.903 116.198 109.190 1.00 142.33 ? 165 THR C O   1 
ATOM   4557 C CB  . THR C 1 165 ? 101.718 113.269 108.769 1.00 142.33 ? 165 THR C CB  1 
ATOM   4558 O OG1 . THR C 1 165 ? 100.870 112.157 109.079 1.00 142.33 ? 165 THR C OG1 1 
ATOM   4559 C CG2 . THR C 1 165 ? 102.890 112.809 107.947 1.00 142.33 ? 165 THR C CG2 1 
ATOM   4560 N N   . SER C 1 166 ? 103.827 115.732 110.216 1.00 139.81 ? 166 SER C N   1 
ATOM   4561 C CA  . SER C 1 166 ? 104.389 117.019 109.969 1.00 139.81 ? 166 SER C CA  1 
ATOM   4562 C C   . SER C 1 166 ? 105.823 116.704 110.270 1.00 139.81 ? 166 SER C C   1 
ATOM   4563 O O   . SER C 1 166 ? 106.408 115.847 109.651 1.00 139.81 ? 166 SER C O   1 
ATOM   4564 C CB  . SER C 1 166 ? 103.837 118.082 110.927 1.00 139.81 ? 166 SER C CB  1 
ATOM   4565 O OG  . SER C 1 166 ? 102.494 118.463 110.644 1.00 139.81 ? 166 SER C OG  1 
ATOM   4566 N N   . LYS C 1 167 ? 106.403 117.464 111.187 1.00 136.97 ? 167 LYS C N   1 
ATOM   4567 C CA  . LYS C 1 167 ? 107.788 117.306 111.600 1.00 136.97 ? 167 LYS C CA  1 
ATOM   4568 C C   . LYS C 1 167 ? 107.857 118.154 112.846 1.00 136.97 ? 167 LYS C C   1 
ATOM   4569 O O   . LYS C 1 167 ? 107.843 117.637 113.963 1.00 136.97 ? 167 LYS C O   1 
ATOM   4570 C CB  . LYS C 1 167 ? 108.739 117.842 110.533 1.00 136.97 ? 167 LYS C CB  1 
ATOM   4571 C CG  . LYS C 1 167 ? 110.059 118.359 111.081 1.00 136.97 ? 167 LYS C CG  1 
ATOM   4572 C CD  . LYS C 1 167 ? 110.889 117.234 111.677 1.00 136.97 ? 167 LYS C CD  1 
ATOM   4573 C CE  . LYS C 1 167 ? 112.377 117.507 111.532 1.00 136.97 ? 167 LYS C CE  1 
ATOM   4574 N NZ  . LYS C 1 167 ? 113.173 116.249 111.490 1.00 136.97 ? 167 LYS C NZ  1 
ATOM   4575 N N   . HIS C 1 168 ? 107.929 119.466 112.656 1.00 135.05 ? 168 HIS C N   1 
ATOM   4576 C CA  . HIS C 1 168 ? 107.895 120.360 113.803 1.00 135.05 ? 168 HIS C CA  1 
ATOM   4577 C C   . HIS C 1 168 ? 106.647 120.101 114.624 1.00 135.05 ? 168 HIS C C   1 
ATOM   4578 O O   . HIS C 1 168 ? 106.654 120.231 115.855 1.00 135.05 ? 168 HIS C O   1 
ATOM   4579 C CB  . HIS C 1 168 ? 107.953 121.811 113.328 1.00 135.05 ? 168 HIS C CB  1 
ATOM   4580 C CG  . HIS C 1 168 ? 107.684 122.811 114.405 1.00 135.05 ? 168 HIS C CG  1 
ATOM   4581 N ND1 . HIS C 1 168 ? 106.457 123.415 114.568 1.00 135.05 ? 168 HIS C ND1 1 
ATOM   4582 C CD2 . HIS C 1 168 ? 108.485 123.316 115.371 1.00 135.05 ? 168 HIS C CD2 1 
ATOM   4583 C CE1 . HIS C 1 168 ? 106.511 124.248 115.592 1.00 135.05 ? 168 HIS C CE1 1 
ATOM   4584 N NE2 . HIS C 1 168 ? 107.731 124.207 116.096 1.00 135.05 ? 168 HIS C NE2 1 
ATOM   4585 N N   . ARG C 1 169 ? 105.567 119.720 113.947 1.00 134.34 ? 169 ARG C N   1 
ATOM   4586 C CA  . ARG C 1 169 ? 104.365 119.277 114.629 1.00 134.34 ? 169 ARG C CA  1 
ATOM   4587 C C   . ARG C 1 169 ? 104.703 118.152 115.596 1.00 134.34 ? 169 ARG C C   1 
ATOM   4588 O O   . ARG C 1 169 ? 104.349 118.211 116.775 1.00 134.34 ? 169 ARG C O   1 
ATOM   4589 C CB  . ARG C 1 169 ? 103.337 118.835 113.587 1.00 134.34 ? 169 ARG C CB  1 
ATOM   4590 C CG  . ARG C 1 169 ? 101.904 118.814 114.057 1.00 134.34 ? 169 ARG C CG  1 
ATOM   4591 C CD  . ARG C 1 169 ? 100.988 118.430 112.907 1.00 134.34 ? 169 ARG C CD  1 
ATOM   4592 N NE  . ARG C 1 169 ? 99.577  118.583 113.247 1.00 134.34 ? 169 ARG C NE  1 
ATOM   4593 C CZ  . ARG C 1 169 ? 98.575  118.307 112.418 1.00 134.34 ? 169 ARG C CZ  1 
ATOM   4594 N NH1 . ARG C 1 169 ? 97.322  118.482 112.809 1.00 134.34 ? 169 ARG C NH1 1 
ATOM   4595 N NH2 . ARG C 1 169 ? 98.827  117.856 111.196 1.00 134.34 ? 169 ARG C NH2 1 
ATOM   4596 N N   . ILE C 1 170 ? 105.443 117.141 115.126 1.00 130.80 ? 170 ILE C N   1 
ATOM   4597 C CA  . ILE C 1 170 ? 105.770 116.009 115.992 1.00 130.80 ? 170 ILE C CA  1 
ATOM   4598 C C   . ILE C 1 170 ? 106.787 116.397 117.058 1.00 130.80 ? 170 ILE C C   1 
ATOM   4599 O O   . ILE C 1 170 ? 106.727 115.892 118.190 1.00 130.80 ? 170 ILE C O   1 
ATOM   4600 C CB  . ILE C 1 170 ? 106.240 114.791 115.173 1.00 130.80 ? 170 ILE C CB  1 
ATOM   4601 C CG1 . ILE C 1 170 ? 106.131 113.530 116.026 1.00 130.80 ? 170 ILE C CG1 1 
ATOM   4602 C CG2 . ILE C 1 170 ? 107.665 114.941 114.708 1.00 130.80 ? 170 ILE C CG2 1 
ATOM   4603 C CD1 . ILE C 1 170 ? 104.725 113.205 116.431 1.00 130.80 ? 170 ILE C CD1 1 
ATOM   4604 N N   . LYS C 1 171 ? 107.656 117.349 116.733 1.00 127.56 ? 171 LYS C N   1 
ATOM   4605 C CA  . LYS C 1 171 ? 108.647 117.830 117.686 1.00 127.56 ? 171 LYS C CA  1 
ATOM   4606 C C   . LYS C 1 171 ? 107.955 118.494 118.879 1.00 127.56 ? 171 LYS C C   1 
ATOM   4607 O O   . LYS C 1 171 ? 108.350 118.291 120.027 1.00 127.56 ? 171 LYS C O   1 
ATOM   4608 C CB  . LYS C 1 171 ? 109.605 118.815 117.015 1.00 127.56 ? 171 LYS C CB  1 
ATOM   4609 C CG  . LYS C 1 171 ? 110.978 118.887 117.665 1.00 127.56 ? 171 LYS C CG  1 
ATOM   4610 C CD  . LYS C 1 171 ? 111.126 120.147 118.502 1.00 127.56 ? 171 LYS C CD  1 
ATOM   4611 C CE  . LYS C 1 171 ? 112.277 120.024 119.485 1.00 127.56 ? 171 LYS C CE  1 
ATOM   4612 N NZ  . LYS C 1 171 ? 112.139 120.970 120.626 1.00 127.56 ? 171 LYS C NZ  1 
ATOM   4613 N N   . ARG C 1 172 ? 106.922 119.289 118.600 1.00 126.40 ? 172 ARG C N   1 
ATOM   4614 C CA  . ARG C 1 172 ? 106.176 119.972 119.645 1.00 126.40 ? 172 ARG C CA  1 
ATOM   4615 C C   . ARG C 1 172 ? 105.245 119.016 120.372 1.00 126.40 ? 172 ARG C C   1 
ATOM   4616 O O   . ARG C 1 172 ? 105.059 119.130 121.586 1.00 126.40 ? 172 ARG C O   1 
ATOM   4617 C CB  . ARG C 1 172 ? 105.420 121.156 119.057 1.00 126.40 ? 172 ARG C CB  1 
ATOM   4618 C CG  . ARG C 1 172 ? 106.365 122.246 118.608 1.00 126.40 ? 172 ARG C CG  1 
ATOM   4619 C CD  . ARG C 1 172 ? 107.121 122.813 119.798 1.00 126.40 ? 172 ARG C CD  1 
ATOM   4620 N NE  . ARG C 1 172 ? 108.325 123.532 119.397 1.00 126.40 ? 172 ARG C NE  1 
ATOM   4621 C CZ  . ARG C 1 172 ? 108.349 124.814 119.047 1.00 126.40 ? 172 ARG C CZ  1 
ATOM   4622 N NH1 . ARG C 1 172 ? 109.493 125.388 118.698 1.00 126.40 ? 172 ARG C NH1 1 
ATOM   4623 N NH2 . ARG C 1 172 ? 107.229 125.518 119.033 1.00 126.40 ? 172 ARG C NH2 1 
ATOM   4624 N N   . ILE C 1 173 ? 104.662 118.050 119.656 1.00 122.66 ? 173 ILE C N   1 
ATOM   4625 C CA  . ILE C 1 173 ? 103.868 117.040 120.350 1.00 122.66 ? 173 ILE C CA  1 
ATOM   4626 C C   . ILE C 1 173 ? 104.692 116.319 121.390 1.00 122.66 ? 173 ILE C C   1 
ATOM   4627 O O   . ILE C 1 173 ? 104.271 116.205 122.542 1.00 122.66 ? 173 ILE C O   1 
ATOM   4628 C CB  . ILE C 1 173 ? 103.247 116.028 119.374 1.00 122.66 ? 173 ILE C CB  1 
ATOM   4629 C CG1 . ILE C 1 173 ? 102.334 116.732 118.396 1.00 122.66 ? 173 ILE C CG1 1 
ATOM   4630 C CG2 . ILE C 1 173 ? 102.489 114.962 120.138 1.00 122.66 ? 173 ILE C CG2 1 
ATOM   4631 C CD1 . ILE C 1 173 ? 101.329 117.571 119.078 1.00 122.66 ? 173 ILE C CD1 1 
ATOM   4632 N N   . MET C 1 174 ? 105.866 115.814 121.017 1.00 120.15 ? 174 MET C N   1 
ATOM   4633 C CA  . MET C 1 174 ? 106.627 115.036 121.987 1.00 120.15 ? 174 MET C CA  1 
ATOM   4634 C C   . MET C 1 174 ? 107.095 115.900 123.153 1.00 120.15 ? 174 MET C C   1 
ATOM   4635 O O   . MET C 1 174 ? 107.010 115.477 124.314 1.00 120.15 ? 174 MET C O   1 
ATOM   4636 C CB  . MET C 1 174 ? 107.786 114.314 121.290 1.00 120.15 ? 174 MET C CB  1 
ATOM   4637 C CG  . MET C 1 174 ? 108.856 115.199 120.700 1.00 120.15 ? 174 MET C CG  1 
ATOM   4638 S SD  . MET C 1 174 ? 110.141 114.259 119.861 1.00 120.15 ? 174 MET C SD  1 
ATOM   4639 C CE  . MET C 1 174 ? 111.203 115.578 119.278 1.00 120.15 ? 174 MET C CE  1 
ATOM   4640 N N   . GLU C 1 175 ? 107.531 117.130 122.875 1.00 114.63 ? 175 GLU C N   1 
ATOM   4641 C CA  . GLU C 1 175 ? 107.970 118.008 123.954 1.00 114.63 ? 175 GLU C CA  1 
ATOM   4642 C C   . GLU C 1 175 ? 106.827 118.337 124.910 1.00 114.63 ? 175 GLU C C   1 
ATOM   4643 O O   . GLU C 1 175 ? 107.001 118.303 126.135 1.00 114.63 ? 175 GLU C O   1 
ATOM   4644 C CB  . GLU C 1 175 ? 108.571 119.281 123.365 1.00 114.63 ? 175 GLU C CB  1 
ATOM   4645 C CG  . GLU C 1 175 ? 109.217 120.187 124.380 1.00 114.63 ? 175 GLU C CG  1 
ATOM   4646 C CD  . GLU C 1 175 ? 109.371 121.601 123.869 1.00 114.63 ? 175 GLU C CD  1 
ATOM   4647 O OE1 . GLU C 1 175 ? 110.240 122.329 124.392 1.00 114.63 ? 175 GLU C OE1 1 
ATOM   4648 O OE2 . GLU C 1 175 ? 108.631 121.985 122.941 1.00 114.63 ? 175 GLU C OE2 1 
ATOM   4649 N N   . GLN C 1 176 ? 105.639 118.629 124.378 1.00 111.01 ? 176 GLN C N   1 
ATOM   4650 C CA  . GLN C 1 176 ? 104.527 119.001 125.241 1.00 111.01 ? 176 GLN C CA  1 
ATOM   4651 C C   . GLN C 1 176 ? 103.930 117.791 125.946 1.00 111.01 ? 176 GLN C C   1 
ATOM   4652 O O   . GLN C 1 176 ? 103.379 117.926 127.042 1.00 111.01 ? 176 GLN C O   1 
ATOM   4653 C CB  . GLN C 1 176 ? 103.461 119.725 124.431 1.00 111.01 ? 176 GLN C CB  1 
ATOM   4654 C CG  . GLN C 1 176 ? 103.937 121.043 123.871 1.00 111.01 ? 176 GLN C CG  1 
ATOM   4655 C CD  . GLN C 1 176 ? 104.315 122.033 124.940 1.00 111.01 ? 176 GLN C CD  1 
ATOM   4656 O OE1 . GLN C 1 176 ? 105.491 122.335 125.128 1.00 111.01 ? 176 GLN C OE1 1 
ATOM   4657 N NE2 . GLN C 1 176 ? 103.320 122.558 125.638 1.00 111.01 ? 176 GLN C NE2 1 
ATOM   4658 N N   . MET C 1 177 ? 104.014 116.604 125.338 1.00 111.89 ? 177 MET C N   1 
ATOM   4659 C CA  . MET C 1 177 ? 103.654 115.391 126.062 1.00 111.89 ? 177 MET C CA  1 
ATOM   4660 C C   . MET C 1 177 ? 104.576 115.166 127.247 1.00 111.89 ? 177 MET C C   1 
ATOM   4661 O O   . MET C 1 177 ? 104.119 114.786 128.329 1.00 111.89 ? 177 MET C O   1 
ATOM   4662 C CB  . MET C 1 177 ? 103.694 114.169 125.150 1.00 111.89 ? 177 MET C CB  1 
ATOM   4663 C CG  . MET C 1 177 ? 102.688 114.116 124.024 1.00 111.89 ? 177 MET C CG  1 
ATOM   4664 S SD  . MET C 1 177 ? 100.987 114.035 124.594 1.00 111.89 ? 177 MET C SD  1 
ATOM   4665 C CE  . MET C 1 177 ? 100.132 114.213 123.035 1.00 111.89 ? 177 MET C CE  1 
ATOM   4666 N N   . TYR C 1 178 ? 105.877 115.376 127.071 1.00 100.42 ? 178 TYR C N   1 
ATOM   4667 C CA  . TYR C 1 178 ? 106.737 115.269 128.241 1.00 100.42 ? 178 TYR C CA  1 
ATOM   4668 C C   . TYR C 1 178 ? 106.368 116.326 129.268 1.00 100.42 ? 178 TYR C C   1 
ATOM   4669 O O   . TYR C 1 178 ? 106.379 116.059 130.477 1.00 100.42 ? 178 TYR C O   1 
ATOM   4670 C CB  . TYR C 1 178 ? 108.208 115.386 127.865 1.00 100.42 ? 178 TYR C CB  1 
ATOM   4671 C CG  . TYR C 1 178 ? 109.100 115.331 129.075 1.00 100.42 ? 178 TYR C CG  1 
ATOM   4672 C CD1 . TYR C 1 178 ? 109.871 116.417 129.444 1.00 100.42 ? 178 TYR C CD1 1 
ATOM   4673 C CD2 . TYR C 1 178 ? 109.145 114.198 129.865 1.00 100.42 ? 178 TYR C CD2 1 
ATOM   4674 C CE1 . TYR C 1 178 ? 110.677 116.367 130.556 1.00 100.42 ? 178 TYR C CE1 1 
ATOM   4675 C CE2 . TYR C 1 178 ? 109.942 114.139 130.980 1.00 100.42 ? 178 TYR C CE2 1 
ATOM   4676 C CZ  . TYR C 1 178 ? 110.708 115.224 131.322 1.00 100.42 ? 178 TYR C CZ  1 
ATOM   4677 O OH  . TYR C 1 178 ? 111.510 115.168 132.435 1.00 100.42 ? 178 TYR C OH  1 
ATOM   4678 N N   . ALA C 1 179 ? 106.036 117.531 128.802 1.00 98.26  ? 179 ALA C N   1 
ATOM   4679 C CA  . ALA C 1 179 ? 105.610 118.578 129.722 1.00 98.26  ? 179 ALA C CA  1 
ATOM   4680 C C   . ALA C 1 179 ? 104.435 118.121 130.567 1.00 98.26  ? 179 ALA C C   1 
ATOM   4681 O O   . ALA C 1 179 ? 104.480 118.200 131.802 1.00 98.26  ? 179 ALA C O   1 
ATOM   4682 C CB  . ALA C 1 179 ? 105.254 119.848 128.957 1.00 98.26  ? 179 ALA C CB  1 
ATOM   4683 N N   . ILE C 1 180 ? 103.388 117.616 129.920 1.00 97.34  ? 180 ILE C N   1 
ATOM   4684 C CA  . ILE C 1 180 ? 102.221 117.183 130.670 1.00 97.34  ? 180 ILE C CA  1 
ATOM   4685 C C   . ILE C 1 180 ? 102.572 116.023 131.578 1.00 97.34  ? 180 ILE C C   1 
ATOM   4686 O O   . ILE C 1 180 ? 102.034 115.922 132.680 1.00 97.34  ? 180 ILE C O   1 
ATOM   4687 C CB  . ILE C 1 180 ? 101.042 116.836 129.745 1.00 97.34  ? 180 ILE C CB  1 
ATOM   4688 C CG1 . ILE C 1 180 ? 99.806  116.560 130.584 1.00 97.34  ? 180 ILE C CG1 1 
ATOM   4689 C CG2 . ILE C 1 180 ? 101.313 115.620 128.918 1.00 97.34  ? 180 ILE C CG2 1 
ATOM   4690 C CD1 . ILE C 1 180 ? 98.603  116.322 129.766 1.00 97.34  ? 180 ILE C CD1 1 
ATOM   4691 N N   . PHE C 1 181 ? 103.485 115.141 131.165 1.00 98.53  ? 181 PHE C N   1 
ATOM   4692 C CA  . PHE C 1 181 ? 103.815 114.020 132.033 1.00 98.53  ? 181 PHE C CA  1 
ATOM   4693 C C   . PHE C 1 181 ? 104.468 114.496 133.319 1.00 98.53  ? 181 PHE C C   1 
ATOM   4694 O O   . PHE C 1 181 ? 104.005 114.158 134.419 1.00 98.53  ? 181 PHE C O   1 
ATOM   4695 C CB  . PHE C 1 181 ? 104.728 113.028 131.319 1.00 98.53  ? 181 PHE C CB  1 
ATOM   4696 C CG  . PHE C 1 181 ? 105.343 112.008 132.236 1.00 98.53  ? 181 PHE C CG  1 
ATOM   4697 C CD1 . PHE C 1 181 ? 106.548 112.251 132.873 1.00 98.53  ? 181 PHE C CD1 1 
ATOM   4698 C CD2 . PHE C 1 181 ? 104.713 110.800 132.459 1.00 98.53  ? 181 PHE C CD2 1 
ATOM   4699 C CE1 . PHE C 1 181 ? 107.105 111.312 133.711 1.00 98.53  ? 181 PHE C CE1 1 
ATOM   4700 C CE2 . PHE C 1 181 ? 105.271 109.855 133.296 1.00 98.53  ? 181 PHE C CE2 1 
ATOM   4701 C CZ  . PHE C 1 181 ? 106.467 110.114 133.922 1.00 98.53  ? 181 PHE C CZ  1 
ATOM   4702 N N   . TYR C 1 182 ? 105.537 115.292 133.217 1.00 92.34  ? 182 TYR C N   1 
ATOM   4703 C CA  . TYR C 1 182 ? 106.195 115.613 134.478 1.00 92.34  ? 182 TYR C CA  1 
ATOM   4704 C C   . TYR C 1 182 ? 105.345 116.540 135.310 1.00 92.34  ? 182 TYR C C   1 
ATOM   4705 O O   . TYR C 1 182 ? 105.382 116.454 136.537 1.00 92.34  ? 182 TYR C O   1 
ATOM   4706 C CB  . TYR C 1 182 ? 107.581 116.246 134.343 1.00 92.34  ? 182 TYR C CB  1 
ATOM   4707 C CG  . TYR C 1 182 ? 107.691 117.599 133.690 1.00 92.34  ? 182 TYR C CG  1 
ATOM   4708 C CD1 . TYR C 1 182 ? 107.888 117.721 132.336 1.00 92.34  ? 182 TYR C CD1 1 
ATOM   4709 C CD2 . TYR C 1 182 ? 107.597 118.760 134.444 1.00 92.34  ? 182 TYR C CD2 1 
ATOM   4710 C CE1 . TYR C 1 182 ? 108.024 118.949 131.747 1.00 92.34  ? 182 TYR C CE1 1 
ATOM   4711 C CE2 . TYR C 1 182 ? 107.707 120.001 133.852 1.00 92.34  ? 182 TYR C CE2 1 
ATOM   4712 C CZ  . TYR C 1 182 ? 107.915 120.085 132.494 1.00 92.34  ? 182 TYR C CZ  1 
ATOM   4713 O OH  . TYR C 1 182 ? 108.032 121.299 131.859 1.00 92.34  ? 182 TYR C OH  1 
ATOM   4714 N N   . THR C 1 183 ? 104.569 117.418 134.678 1.00 89.69  ? 183 THR C N   1 
ATOM   4715 C CA  . THR C 1 183 ? 103.725 118.292 135.471 1.00 89.69  ? 183 THR C CA  1 
ATOM   4716 C C   . THR C 1 183 ? 102.574 117.542 136.118 1.00 89.69  ? 183 THR C C   1 
ATOM   4717 O O   . THR C 1 183 ? 102.188 117.875 137.237 1.00 89.69  ? 183 THR C O   1 
ATOM   4718 C CB  . THR C 1 183 ? 103.198 119.427 134.615 1.00 89.69  ? 183 THR C CB  1 
ATOM   4719 O OG1 . THR C 1 183 ? 104.297 120.082 133.977 1.00 89.69  ? 183 THR C OG1 1 
ATOM   4720 C CG2 . THR C 1 183 ? 102.540 120.411 135.487 1.00 89.69  ? 183 THR C CG2 1 
ATOM   4721 N N   . GLY C 1 184 ? 102.030 116.520 135.460 1.00 89.45  ? 184 GLY C N   1 
ATOM   4722 C CA  . GLY C 1 184 ? 101.004 115.717 136.092 1.00 89.45  ? 184 GLY C CA  1 
ATOM   4723 C C   . GLY C 1 184 ? 101.560 114.866 137.214 1.00 89.45  ? 184 GLY C C   1 
ATOM   4724 O O   . GLY C 1 184 ? 100.825 114.428 138.098 1.00 89.45  ? 184 GLY C O   1 
ATOM   4725 N N   . VAL C 1 185 ? 102.860 114.584 137.172 1.00 89.73  ? 185 VAL C N   1 
ATOM   4726 C CA  . VAL C 1 185 ? 103.477 113.901 138.306 1.00 89.73  ? 185 VAL C CA  1 
ATOM   4727 C C   . VAL C 1 185 ? 103.731 114.883 139.447 1.00 89.73  ? 185 VAL C C   1 
ATOM   4728 O O   . VAL C 1 185 ? 103.432 114.602 140.613 1.00 89.73  ? 185 VAL C O   1 
ATOM   4729 C CB  . VAL C 1 185 ? 104.765 113.186 137.870 1.00 89.73  ? 185 VAL C CB  1 
ATOM   4730 C CG1 . VAL C 1 185 ? 105.559 112.758 139.083 1.00 89.73  ? 185 VAL C CG1 1 
ATOM   4731 C CG2 . VAL C 1 185 ? 104.417 111.978 137.029 1.00 89.73  ? 185 VAL C CG2 1 
ATOM   4732 N N   . SER C 1 186 ? 104.266 116.059 139.123 1.00 86.19  ? 186 SER C N   1 
ATOM   4733 C CA  . SER C 1 186 ? 104.737 117.014 140.117 1.00 86.19  ? 186 SER C CA  1 
ATOM   4734 C C   . SER C 1 186 ? 103.650 117.905 140.693 1.00 86.19  ? 186 SER C C   1 
ATOM   4735 O O   . SER C 1 186 ? 103.901 118.566 141.703 1.00 86.19  ? 186 SER C O   1 
ATOM   4736 C CB  . SER C 1 186 ? 105.815 117.905 139.514 1.00 86.19  ? 186 SER C CB  1 
ATOM   4737 O OG  . SER C 1 186 ? 106.156 118.937 140.414 1.00 86.19  ? 186 SER C OG  1 
ATOM   4738 N N   . GLY C 1 187 ? 102.476 117.977 140.082 1.00 89.43  ? 187 GLY C N   1 
ATOM   4739 C CA  . GLY C 1 187 ? 101.421 118.802 140.609 1.00 89.43  ? 187 GLY C CA  1 
ATOM   4740 C C   . GLY C 1 187 ? 100.725 118.133 141.769 1.00 89.43  ? 187 GLY C C   1 
ATOM   4741 O O   . GLY C 1 187 ? 100.823 118.574 142.917 1.00 89.43  ? 187 GLY C O   1 
ATOM   4742 N N   . PRO C 1 188 ? 100.036 117.023 141.494 1.00 90.18  ? 188 PRO C N   1 
ATOM   4743 C CA  . PRO C 1 188 ? 99.333  116.322 142.574 1.00 90.18  ? 188 PRO C CA  1 
ATOM   4744 C C   . PRO C 1 188 ? 100.239 115.936 143.718 1.00 90.18  ? 188 PRO C C   1 
ATOM   4745 O O   . PRO C 1 188 ? 99.785  115.908 144.862 1.00 90.18  ? 188 PRO C O   1 
ATOM   4746 C CB  . PRO C 1 188 ? 98.750  115.083 141.880 1.00 90.18  ? 188 PRO C CB  1 
ATOM   4747 C CG  . PRO C 1 188 ? 99.066  115.215 140.445 1.00 90.18  ? 188 PRO C CG  1 
ATOM   4748 C CD  . PRO C 1 188 ? 99.587  116.575 140.172 1.00 90.18  ? 188 PRO C CD  1 
ATOM   4749 N N   . PHE C 1 189 ? 101.510 115.650 143.458 1.00 89.75  ? 189 PHE C N   1 
ATOM   4750 C CA  . PHE C 1 189 ? 102.432 115.417 144.561 1.00 89.75  ? 189 PHE C CA  1 
ATOM   4751 C C   . PHE C 1 189 ? 102.605 116.680 145.394 1.00 89.75  ? 189 PHE C C   1 
ATOM   4752 O O   . PHE C 1 189 ? 102.693 116.614 146.626 1.00 89.75  ? 189 PHE C O   1 
ATOM   4753 C CB  . PHE C 1 189 ? 103.771 114.932 144.023 1.00 89.75  ? 189 PHE C CB  1 
ATOM   4754 C CG  . PHE C 1 189 ? 104.722 114.516 145.085 1.00 89.75  ? 189 PHE C CG  1 
ATOM   4755 C CD1 . PHE C 1 189 ? 104.540 113.325 145.755 1.00 89.75  ? 189 PHE C CD1 1 
ATOM   4756 C CD2 . PHE C 1 189 ? 105.808 115.297 145.406 1.00 89.75  ? 189 PHE C CD2 1 
ATOM   4757 C CE1 . PHE C 1 189 ? 105.415 112.929 146.735 1.00 89.75  ? 189 PHE C CE1 1 
ATOM   4758 C CE2 . PHE C 1 189 ? 106.685 114.902 146.382 1.00 89.75  ? 189 PHE C CE2 1 
ATOM   4759 C CZ  . PHE C 1 189 ? 106.491 113.722 147.047 1.00 89.75  ? 189 PHE C CZ  1 
ATOM   4760 N N   . GLY C 1 190 ? 102.637 117.840 144.741 1.00 90.39  ? 190 GLY C N   1 
ATOM   4761 C CA  . GLY C 1 190 ? 102.695 119.088 145.479 1.00 90.39  ? 190 GLY C CA  1 
ATOM   4762 C C   . GLY C 1 190 ? 101.456 119.321 146.319 1.00 90.39  ? 190 GLY C C   1 
ATOM   4763 O O   . GLY C 1 190 ? 101.546 119.715 147.483 1.00 90.39  ? 190 GLY C O   1 
ATOM   4764 N N   . ILE C 1 191 ? 100.277 119.083 145.741 1.00 90.91  ? 191 ILE C N   1 
ATOM   4765 C CA  . ILE C 1 191 ? 99.056  119.238 146.530 1.00 90.91  ? 191 ILE C CA  1 
ATOM   4766 C C   . ILE C 1 191 ? 99.004  118.208 147.649 1.00 90.91  ? 191 ILE C C   1 
ATOM   4767 O O   . ILE C 1 191 ? 98.452  118.479 148.718 1.00 90.91  ? 191 ILE C O   1 
ATOM   4768 C CB  . ILE C 1 191 ? 97.787  119.193 145.653 1.00 90.91  ? 191 ILE C CB  1 
ATOM   4769 C CG1 . ILE C 1 191 ? 97.714  120.382 144.698 1.00 90.91  ? 191 ILE C CG1 1 
ATOM   4770 C CG2 . ILE C 1 191 ? 96.540  119.197 146.501 1.00 90.91  ? 191 ILE C CG2 1 
ATOM   4771 C CD1 . ILE C 1 191 ? 98.338  120.168 143.372 1.00 90.91  ? 191 ILE C CD1 1 
ATOM   4772 N N   . TYR C 1 192 ? 99.582  117.028 147.448 1.00 94.37  ? 192 TYR C N   1 
ATOM   4773 C CA  . TYR C 1 192 ? 99.631  116.053 148.529 1.00 94.37  ? 192 TYR C CA  1 
ATOM   4774 C C   . TYR C 1 192 ? 100.488 116.575 149.671 1.00 94.37  ? 192 TYR C C   1 
ATOM   4775 O O   . TYR C 1 192 ? 100.055 116.609 150.827 1.00 94.37  ? 192 TYR C O   1 
ATOM   4776 C CB  . TYR C 1 192 ? 100.182 114.727 148.008 1.00 94.37  ? 192 TYR C CB  1 
ATOM   4777 C CG  . TYR C 1 192 ? 100.331 113.629 149.040 1.00 94.37  ? 192 TYR C CG  1 
ATOM   4778 C CD1 . TYR C 1 192 ? 99.657  113.676 150.251 1.00 94.37  ? 192 TYR C CD1 1 
ATOM   4779 C CD2 . TYR C 1 192 ? 101.154 112.542 148.798 1.00 94.37  ? 192 TYR C CD2 1 
ATOM   4780 C CE1 . TYR C 1 192 ? 99.797  112.676 151.185 1.00 94.37  ? 192 TYR C CE1 1 
ATOM   4781 C CE2 . TYR C 1 192 ? 101.301 111.536 149.727 1.00 94.37  ? 192 TYR C CE2 1 
ATOM   4782 C CZ  . TYR C 1 192 ? 100.618 111.609 150.919 1.00 94.37  ? 192 TYR C CZ  1 
ATOM   4783 O OH  . TYR C 1 192 ? 100.756 110.610 151.852 1.00 94.37  ? 192 TYR C OH  1 
ATOM   4784 N N   . CYS C 1 193 ? 101.699 117.020 149.359 1.00 95.95  ? 193 CYS C N   1 
ATOM   4785 C CA  . CYS C 1 193 ? 102.611 117.537 150.369 1.00 95.95  ? 193 CYS C CA  1 
ATOM   4786 C C   . CYS C 1 193 ? 102.081 118.793 151.043 1.00 95.95  ? 193 CYS C C   1 
ATOM   4787 O O   . CYS C 1 193 ? 102.466 119.079 152.178 1.00 95.95  ? 193 CYS C O   1 
ATOM   4788 C CB  . CYS C 1 193 ? 103.975 117.819 149.747 1.00 95.95  ? 193 CYS C CB  1 
ATOM   4789 S SG  . CYS C 1 193 ? 105.191 118.396 150.924 1.00 95.95  ? 193 CYS C SG  1 
ATOM   4790 N N   . MET C 1 194 ? 101.219 119.546 150.370 1.00 92.94  ? 194 MET C N   1 
ATOM   4791 C CA  . MET C 1 194 ? 100.537 120.680 150.973 1.00 92.94  ? 194 MET C CA  1 
ATOM   4792 C C   . MET C 1 194 ? 99.293  120.272 151.746 1.00 92.94  ? 194 MET C C   1 
ATOM   4793 O O   . MET C 1 194 ? 98.830  121.034 152.597 1.00 92.94  ? 194 MET C O   1 
ATOM   4794 C CB  . MET C 1 194 ? 100.147 121.687 149.891 1.00 92.94  ? 194 MET C CB  1 
ATOM   4795 C CG  . MET C 1 194 ? 99.610  122.998 150.401 1.00 92.94  ? 194 MET C CG  1 
ATOM   4796 S SD  . MET C 1 194 ? 98.540  123.774 149.187 1.00 92.94  ? 194 MET C SD  1 
ATOM   4797 C CE  . MET C 1 194 ? 98.535  125.453 149.774 1.00 92.94  ? 194 MET C CE  1 
ATOM   4798 N N   . TYR C 1 195 ? 98.759  119.084 151.486 1.00 99.46  ? 195 TYR C N   1 
ATOM   4799 C CA  . TYR C 1 195 ? 97.524  118.620 152.095 1.00 99.46  ? 195 TYR C CA  1 
ATOM   4800 C C   . TYR C 1 195 ? 97.706  118.286 153.567 1.00 99.46  ? 195 TYR C C   1 
ATOM   4801 O O   . TYR C 1 195 ? 97.016  118.848 154.422 1.00 99.46  ? 195 TYR C O   1 
ATOM   4802 C CB  . TYR C 1 195 ? 97.007  117.402 151.332 1.00 99.46  ? 195 TYR C CB  1 
ATOM   4803 C CG  . TYR C 1 195 ? 95.770  116.770 151.914 1.00 99.46  ? 195 TYR C CG  1 
ATOM   4804 C CD1 . TYR C 1 195 ? 94.530  117.358 151.756 1.00 99.46  ? 195 TYR C CD1 1 
ATOM   4805 C CD2 . TYR C 1 195 ? 95.843  115.573 152.605 1.00 99.46  ? 195 TYR C CD2 1 
ATOM   4806 C CE1 . TYR C 1 195 ? 93.401  116.776 152.280 1.00 99.46  ? 195 TYR C CE1 1 
ATOM   4807 C CE2 . TYR C 1 195 ? 94.721  114.988 153.131 1.00 99.46  ? 195 TYR C CE2 1 
ATOM   4808 C CZ  . TYR C 1 195 ? 93.503  115.592 152.966 1.00 99.46  ? 195 TYR C CZ  1 
ATOM   4809 O OH  . TYR C 1 195 ? 92.376  115.009 153.491 1.00 99.46  ? 195 TYR C OH  1 
ATOM   4810 N N   . HIS C 1 196 ? 98.627  117.380 153.883 1.00 98.71  ? 196 HIS C N   1 
ATOM   4811 C CA  . HIS C 1 196 ? 98.822  116.999 155.274 1.00 98.71  ? 196 HIS C CA  1 
ATOM   4812 C C   . HIS C 1 196 ? 99.811  117.939 155.946 1.00 98.71  ? 196 HIS C C   1 
ATOM   4813 O O   . HIS C 1 196 ? 100.793 117.505 156.554 1.00 98.71  ? 196 HIS C O   1 
ATOM   4814 C CB  . HIS C 1 196 ? 99.270  115.540 155.378 1.00 98.71  ? 196 HIS C CB  1 
ATOM   4815 C CG  . HIS C 1 196 ? 100.617 115.272 154.792 1.00 98.71  ? 196 HIS C CG  1 
ATOM   4816 N ND1 . HIS C 1 196 ? 101.786 115.506 155.483 1.00 98.71  ? 196 HIS C ND1 1 
ATOM   4817 C CD2 . HIS C 1 196 ? 100.984 114.771 153.591 1.00 98.71  ? 196 HIS C CD2 1 
ATOM   4818 C CE1 . HIS C 1 196 ? 102.815 115.169 154.728 1.00 98.71  ? 196 HIS C CE1 1 
ATOM   4819 N NE2 . HIS C 1 196 ? 102.355 114.719 153.575 1.00 98.71  ? 196 HIS C NE2 1 
ATOM   4820 N N   . SER C 1 197 ? 99.547  119.236 155.847 1.00 95.92  ? 197 SER C N   1 
ATOM   4821 C CA  . SER C 1 197 ? 100.337 120.238 156.540 1.00 95.92  ? 197 SER C CA  1 
ATOM   4822 C C   . SER C 1 197 ? 99.449  121.447 156.766 1.00 95.92  ? 197 SER C C   1 
ATOM   4823 O O   . SER C 1 197 ? 98.398  121.584 156.135 1.00 95.92  ? 197 SER C O   1 
ATOM   4824 C CB  . SER C 1 197 ? 101.587 120.627 155.754 1.00 95.92  ? 197 SER C CB  1 
ATOM   4825 O OG  . SER C 1 197 ? 101.237 121.349 154.595 1.00 95.92  ? 197 SER C OG  1 
ATOM   4826 N N   . ASP C 1 198 ? 99.884  122.327 157.659 1.00 95.13  ? 198 ASP C N   1 
ATOM   4827 C CA  . ASP C 1 198 ? 99.065  123.459 158.068 1.00 95.13  ? 198 ASP C CA  1 
ATOM   4828 C C   . ASP C 1 198 ? 98.963  124.535 156.993 1.00 95.13  ? 198 ASP C C   1 
ATOM   4829 O O   . ASP C 1 198 ? 98.508  125.648 157.270 1.00 95.13  ? 198 ASP C O   1 
ATOM   4830 C CB  . ASP C 1 198 ? 99.605  124.039 159.377 1.00 95.13  ? 198 ASP C CB  1 
ATOM   4831 C CG  . ASP C 1 198 ? 101.014 124.578 159.247 1.00 95.13  ? 198 ASP C CG  1 
ATOM   4832 O OD1 . ASP C 1 198 ? 101.602 124.473 158.154 1.00 95.13  ? 198 ASP C OD1 1 
ATOM   4833 O OD2 . ASP C 1 198 ? 101.543 125.099 160.250 1.00 95.13  ? 198 ASP C OD2 1 
ATOM   4834 N N   . LEU C 1 199 ? 99.376  124.216 155.770 1.00 91.62  ? 199 LEU C N   1 
ATOM   4835 C CA  . LEU C 1 199 ? 99.351  125.155 154.659 1.00 91.62  ? 199 LEU C CA  1 
ATOM   4836 C C   . LEU C 1 199 ? 98.056  125.125 153.862 1.00 91.62  ? 199 LEU C C   1 
ATOM   4837 O O   . LEU C 1 199 ? 97.948  125.856 152.875 1.00 91.62  ? 199 LEU C O   1 
ATOM   4838 C CB  . LEU C 1 199 ? 100.515 124.875 153.713 1.00 91.62  ? 199 LEU C CB  1 
ATOM   4839 C CG  . LEU C 1 199 ? 101.892 125.408 154.076 1.00 91.62  ? 199 LEU C CG  1 
ATOM   4840 C CD1 . LEU C 1 199 ? 102.916 124.838 153.132 1.00 91.62  ? 199 LEU C CD1 1 
ATOM   4841 C CD2 . LEU C 1 199 ? 101.882 126.908 153.981 1.00 91.62  ? 199 LEU C CD2 1 
ATOM   4842 N N   . TRP C 1 200 ? 97.075  124.321 154.265 1.00 97.27  ? 200 TRP C N   1 
ATOM   4843 C CA  . TRP C 1 200 ? 95.968  123.965 153.381 1.00 97.27  ? 200 TRP C CA  1 
ATOM   4844 C C   . TRP C 1 200 ? 95.224  125.194 152.868 1.00 97.27  ? 200 TRP C C   1 
ATOM   4845 O O   . TRP C 1 200 ? 94.881  126.096 153.636 1.00 97.27  ? 200 TRP C O   1 
ATOM   4846 C CB  . TRP C 1 200 ? 95.006  123.037 154.114 1.00 97.27  ? 200 TRP C CB  1 
ATOM   4847 C CG  . TRP C 1 200 ? 94.005  122.374 153.226 1.00 97.27  ? 200 TRP C CG  1 
ATOM   4848 C CD1 . TRP C 1 200 ? 92.667  122.276 153.442 1.00 97.27  ? 200 TRP C CD1 1 
ATOM   4849 C CD2 . TRP C 1 200 ? 94.264  121.683 151.999 1.00 97.27  ? 200 TRP C CD2 1 
ATOM   4850 N NE1 . TRP C 1 200 ? 92.071  121.584 152.420 1.00 97.27  ? 200 TRP C NE1 1 
ATOM   4851 C CE2 . TRP C 1 200 ? 93.033  121.207 151.523 1.00 97.27  ? 200 TRP C CE2 1 
ATOM   4852 C CE3 . TRP C 1 200 ? 95.415  121.426 151.256 1.00 97.27  ? 200 TRP C CE3 1 
ATOM   4853 C CZ2 . TRP C 1 200 ? 92.921  120.494 150.341 1.00 97.27  ? 200 TRP C CZ2 1 
ATOM   4854 C CZ3 . TRP C 1 200 ? 95.300  120.721 150.084 1.00 97.27  ? 200 TRP C CZ3 1 
ATOM   4855 C CH2 . TRP C 1 200 ? 94.064  120.263 149.638 1.00 97.27  ? 200 TRP C CH2 1 
ATOM   4856 N N   . PHE C 1 201 ? 94.912  125.143 151.637 1.00 100.83 ? 201 PHE C N   1 
ATOM   4857 C CA  . PHE C 1 201 ? 94.358  126.243 151.001 1.00 100.83 ? 201 PHE C CA  1 
ATOM   4858 C C   . PHE C 1 201 ? 94.872  127.580 151.125 1.00 100.83 ? 201 PHE C C   1 
ATOM   4859 O O   . PHE C 1 201 ? 94.140  128.488 151.189 1.00 100.83 ? 201 PHE C O   1 
ATOM   4860 C CB  . PHE C 1 201 ? 92.972  126.140 150.648 1.00 100.83 ? 201 PHE C CB  1 
ATOM   4861 C CG  . PHE C 1 201 ? 92.888  125.798 149.289 1.00 100.83 ? 201 PHE C CG  1 
ATOM   4862 C CD1 . PHE C 1 201 ? 92.675  126.736 148.377 1.00 100.83 ? 201 PHE C CD1 1 
ATOM   4863 C CD2 . PHE C 1 201 ? 93.306  124.585 148.921 1.00 100.83 ? 201 PHE C CD2 1 
ATOM   4864 C CE1 . PHE C 1 201 ? 92.715  126.430 147.080 1.00 100.83 ? 201 PHE C CE1 1 
ATOM   4865 C CE2 . PHE C 1 201 ? 93.356  124.265 147.635 1.00 100.83 ? 201 PHE C CE2 1 
ATOM   4866 C CZ  . PHE C 1 201 ? 93.058  125.196 146.708 1.00 100.83 ? 201 PHE C CZ  1 
ATOM   4867 N N   . PHE C 1 202 ? 96.164  127.653 150.945 1.00 94.16  ? 202 PHE C N   1 
ATOM   4868 C CA  . PHE C 1 202 ? 96.925  128.838 150.979 1.00 94.16  ? 202 PHE C CA  1 
ATOM   4869 C C   . PHE C 1 202 ? 96.562  129.649 152.117 1.00 94.16  ? 202 PHE C C   1 
ATOM   4870 O O   . PHE C 1 202 ? 96.029  130.698 152.001 1.00 94.16  ? 202 PHE C O   1 
ATOM   4871 C CB  . PHE C 1 202 ? 96.777  129.588 149.734 1.00 94.16  ? 202 PHE C CB  1 
ATOM   4872 C CG  . PHE C 1 202 ? 97.094  128.799 148.549 1.00 94.16  ? 202 PHE C CG  1 
ATOM   4873 C CD1 . PHE C 1 202 ? 98.267  128.927 147.954 1.00 94.16  ? 202 PHE C CD1 1 
ATOM   4874 C CD2 . PHE C 1 202 ? 96.206  127.967 148.042 1.00 94.16  ? 202 PHE C CD2 1 
ATOM   4875 C CE1 . PHE C 1 202 ? 98.559  128.227 146.857 1.00 94.16  ? 202 PHE C CE1 1 
ATOM   4876 C CE2 . PHE C 1 202 ? 96.461  127.285 146.949 1.00 94.16  ? 202 PHE C CE2 1 
ATOM   4877 C CZ  . PHE C 1 202 ? 97.648  127.403 146.361 1.00 94.16  ? 202 PHE C CZ  1 
ATOM   4878 N N   . ASN C 1 203 ? 96.972  129.176 153.251 1.00 92.31  ? 203 ASN C N   1 
ATOM   4879 C CA  . ASN C 1 203 ? 96.651  129.846 154.421 1.00 92.31  ? 203 ASN C CA  1 
ATOM   4880 C C   . ASN C 1 203 ? 97.944  130.302 154.800 1.00 92.31  ? 203 ASN C C   1 
ATOM   4881 O O   . ASN C 1 203 ? 98.648  129.642 155.431 1.00 92.31  ? 203 ASN C O   1 
ATOM   4882 C CB  . ASN C 1 203 ? 96.163  128.829 155.373 1.00 92.31  ? 203 ASN C CB  1 
ATOM   4883 C CG  . ASN C 1 203 ? 96.353  129.254 156.735 1.00 92.31  ? 203 ASN C CG  1 
ATOM   4884 O OD1 . ASN C 1 203 ? 96.366  130.424 156.981 1.00 92.31  ? 203 ASN C OD1 1 
ATOM   4885 N ND2 . ASN C 1 203 ? 96.597  128.327 157.621 1.00 92.31  ? 203 ASN C ND2 1 
ATOM   4886 N N   . THR C 1 204 ? 98.264  131.487 154.287 1.00 87.77  ? 204 THR C N   1 
ATOM   4887 C CA  . THR C 1 204 ? 99.531  132.150 154.520 1.00 87.77  ? 204 THR C CA  1 
ATOM   4888 C C   . THR C 1 204 ? 99.816  132.203 156.002 1.00 87.77  ? 204 THR C C   1 
ATOM   4889 O O   . THR C 1 204 ? 100.912 131.856 156.437 1.00 87.77  ? 204 THR C O   1 
ATOM   4890 C CB  . THR C 1 204 ? 99.533  133.582 153.955 1.00 87.77  ? 204 THR C CB  1 
ATOM   4891 O OG1 . THR C 1 204 ? 98.410  134.305 154.473 1.00 87.77  ? 204 THR C OG1 1 
ATOM   4892 C CG2 . THR C 1 204 ? 99.455  133.554 152.436 1.00 87.77  ? 204 THR C CG2 1 
ATOM   4893 N N   . LYS C 1 205 ? 98.835  132.635 156.788 1.00 89.60  ? 205 LYS C N   1 
ATOM   4894 C CA  . LYS C 1 205 ? 99.092  132.680 158.222 1.00 89.60  ? 205 LYS C CA  1 
ATOM   4895 C C   . LYS C 1 205 ? 100.002 131.527 158.675 1.00 89.60  ? 205 LYS C C   1 
ATOM   4896 O O   . LYS C 1 205 ? 100.482 131.526 159.808 1.00 89.60  ? 205 LYS C O   1 
ATOM   4897 C CB  . LYS C 1 205 ? 97.777  132.648 159.002 1.00 89.60  ? 205 LYS C CB  1 
ATOM   4898 C CG  . LYS C 1 205 ? 97.946  132.792 160.506 1.00 89.60  ? 205 LYS C CG  1 
ATOM   4899 C CD  . LYS C 1 205 ? 98.146  131.441 161.171 1.00 89.60  ? 205 LYS C CD  1 
ATOM   4900 C CE  . LYS C 1 205 ? 98.698  131.594 162.580 1.00 89.60  ? 205 LYS C CE  1 
ATOM   4901 N NZ  . LYS C 1 205 ? 99.064  130.283 163.181 1.00 89.60  ? 205 LYS C NZ  1 
ATOM   4902 N N   . ALA C 1 206 ? 100.241 130.552 157.795 1.00 86.67  ? 206 ALA C N   1 
ATOM   4903 C CA  . ALA C 1 206 ? 101.090 129.421 158.135 1.00 86.67  ? 206 ALA C CA  1 
ATOM   4904 C C   . ALA C 1 206 ? 102.467 129.470 157.502 1.00 86.67  ? 206 ALA C C   1 
ATOM   4905 O O   . ALA C 1 206 ? 103.325 128.666 157.875 1.00 86.67  ? 206 ALA C O   1 
ATOM   4906 C CB  . ALA C 1 206 ? 100.415 128.108 157.731 1.00 86.67  ? 206 ALA C CB  1 
ATOM   4907 N N   . MET C 1 207 ? 102.704 130.377 156.560 1.00 82.76  ? 207 MET C N   1 
ATOM   4908 C CA  . MET C 1 207 ? 104.011 130.456 155.922 1.00 82.76  ? 207 MET C CA  1 
ATOM   4909 C C   . MET C 1 207 ? 105.019 131.241 156.742 1.00 82.76  ? 207 MET C C   1 
ATOM   4910 O O   . MET C 1 207 ? 106.202 131.258 156.391 1.00 82.76  ? 207 MET C O   1 
ATOM   4911 C CB  . MET C 1 207 ? 103.875 131.076 154.532 1.00 82.76  ? 207 MET C CB  1 
ATOM   4912 C CG  . MET C 1 207 ? 102.873 130.366 153.642 1.00 82.76  ? 207 MET C CG  1 
ATOM   4913 S SD  . MET C 1 207 ? 102.893 130.915 151.928 1.00 82.76  ? 207 MET C SD  1 
ATOM   4914 C CE  . MET C 1 207 ? 102.850 132.689 152.129 1.00 82.76  ? 207 MET C CE  1 
ATOM   4915 N N   . TYR C 1 208 ? 104.583 131.883 157.821 1.00 80.82  ? 208 TYR C N   1 
ATOM   4916 C CA  . TYR C 1 208 ? 105.448 132.686 158.662 1.00 80.82  ? 208 TYR C CA  1 
ATOM   4917 C C   . TYR C 1 208 ? 105.330 132.359 160.138 1.00 80.82  ? 208 TYR C C   1 
ATOM   4918 O O   . TYR C 1 208 ? 106.152 132.837 160.923 1.00 80.82  ? 208 TYR C O   1 
ATOM   4919 C CB  . TYR C 1 208 ? 105.137 134.175 158.476 1.00 80.82  ? 208 TYR C CB  1 
ATOM   4920 C CG  . TYR C 1 208 ? 104.931 134.591 157.050 1.00 80.82  ? 208 TYR C CG  1 
ATOM   4921 C CD1 . TYR C 1 208 ? 105.977 134.583 156.151 1.00 80.82  ? 208 TYR C CD1 1 
ATOM   4922 C CD2 . TYR C 1 208 ? 103.687 134.975 156.597 1.00 80.82  ? 208 TYR C CD2 1 
ATOM   4923 C CE1 . TYR C 1 208 ? 105.793 134.963 154.847 1.00 80.82  ? 208 TYR C CE1 1 
ATOM   4924 C CE2 . TYR C 1 208 ? 103.496 135.353 155.297 1.00 80.82  ? 208 TYR C CE2 1 
ATOM   4925 C CZ  . TYR C 1 208 ? 104.551 135.343 154.426 1.00 80.82  ? 208 TYR C CZ  1 
ATOM   4926 O OH  . TYR C 1 208 ? 104.364 135.717 153.121 1.00 80.82  ? 208 TYR C OH  1 
ATOM   4927 N N   . ARG C 1 209 ? 104.339 131.572 160.541 1.00 88.21  ? 209 ARG C N   1 
ATOM   4928 C CA  . ARG C 1 209 ? 104.068 131.340 161.952 1.00 88.21  ? 209 ARG C CA  1 
ATOM   4929 C C   . ARG C 1 209 ? 105.242 130.653 162.633 1.00 88.21  ? 209 ARG C C   1 
ATOM   4930 O O   . ARG C 1 209 ? 105.415 130.761 163.849 1.00 88.21  ? 209 ARG C O   1 
ATOM   4931 C CB  . ARG C 1 209 ? 102.787 130.525 162.107 1.00 88.21  ? 209 ARG C CB  1 
ATOM   4932 C CG  . ARG C 1 209 ? 102.330 130.355 163.532 1.00 88.21  ? 209 ARG C CG  1 
ATOM   4933 C CD  . ARG C 1 209 ? 102.504 128.924 163.978 1.00 88.21  ? 209 ARG C CD  1 
ATOM   4934 N NE  . ARG C 1 209 ? 101.694 128.027 163.163 1.00 88.21  ? 209 ARG C NE  1 
ATOM   4935 C CZ  . ARG C 1 209 ? 101.807 126.705 163.168 1.00 88.21  ? 209 ARG C CZ  1 
ATOM   4936 N NH1 . ARG C 1 209 ? 102.701 126.118 163.949 1.00 88.21  ? 209 ARG C NH1 1 
ATOM   4937 N NH2 . ARG C 1 209 ? 101.025 125.970 162.392 1.00 88.21  ? 209 ARG C NH2 1 
ATOM   4938 N N   . THR C 1 210 ? 106.063 129.953 161.857 1.00 81.45  ? 210 THR C N   1 
ATOM   4939 C CA  . THR C 1 210 ? 107.321 129.419 162.371 1.00 81.45  ? 210 THR C CA  1 
ATOM   4940 C C   . THR C 1 210 ? 108.374 129.618 161.281 1.00 81.45  ? 210 THR C C   1 
ATOM   4941 O O   . THR C 1 210 ? 108.547 128.763 160.411 1.00 81.45  ? 210 THR C O   1 
ATOM   4942 C CB  . THR C 1 210 ? 107.169 127.961 162.800 1.00 81.45  ? 210 THR C CB  1 
ATOM   4943 O OG1 . THR C 1 210 ? 108.390 127.487 163.379 1.00 81.45  ? 210 THR C OG1 1 
ATOM   4944 C CG2 . THR C 1 210 ? 106.673 127.042 161.681 1.00 81.45  ? 210 THR C CG2 1 
ATOM   4945 N N   . TYR C 1 211 ? 109.057 130.754 161.327 1.00 71.96  ? 211 TYR C N   1 
ATOM   4946 C CA  . TYR C 1 211 ? 109.812 131.101 160.135 1.00 71.96  ? 211 TYR C CA  1 
ATOM   4947 C C   . TYR C 1 211 ? 111.095 130.295 159.970 1.00 71.96  ? 211 TYR C C   1 
ATOM   4948 O O   . TYR C 1 211 ? 111.254 129.655 158.926 1.00 71.96  ? 211 TYR C O   1 
ATOM   4949 C CB  . TYR C 1 211 ? 110.167 132.583 160.077 1.00 71.96  ? 211 TYR C CB  1 
ATOM   4950 C CG  . TYR C 1 211 ? 111.320 132.787 159.135 1.00 71.96  ? 211 TYR C CG  1 
ATOM   4951 C CD1 . TYR C 1 211 ? 111.200 132.483 157.791 1.00 71.96  ? 211 TYR C CD1 1 
ATOM   4952 C CD2 . TYR C 1 211 ? 112.543 133.219 159.594 1.00 71.96  ? 211 TYR C CD2 1 
ATOM   4953 C CE1 . TYR C 1 211 ? 112.256 132.628 156.940 1.00 71.96  ? 211 TYR C CE1 1 
ATOM   4954 C CE2 . TYR C 1 211 ? 113.601 133.372 158.743 1.00 71.96  ? 211 TYR C CE2 1 
ATOM   4955 C CZ  . TYR C 1 211 ? 113.452 133.077 157.422 1.00 71.96  ? 211 TYR C CZ  1 
ATOM   4956 O OH  . TYR C 1 211 ? 114.515 133.232 156.577 1.00 71.96  ? 211 TYR C OH  1 
ATOM   4957 N N   . PRO C 1 212 ? 112.035 130.305 160.925 1.00 74.56  ? 212 PRO C N   1 
ATOM   4958 C CA  . PRO C 1 212 ? 113.387 129.821 160.596 1.00 74.56  ? 212 PRO C CA  1 
ATOM   4959 C C   . PRO C 1 212 ? 113.411 128.458 159.934 1.00 74.56  ? 212 PRO C C   1 
ATOM   4960 O O   . PRO C 1 212 ? 114.287 128.228 159.100 1.00 74.56  ? 212 PRO C O   1 
ATOM   4961 C CB  . PRO C 1 212 ? 114.106 129.808 161.945 1.00 74.56  ? 212 PRO C CB  1 
ATOM   4962 C CG  . PRO C 1 212 ? 113.371 130.733 162.793 1.00 74.56  ? 212 PRO C CG  1 
ATOM   4963 C CD  . PRO C 1 212 ? 111.969 130.847 162.294 1.00 74.56  ? 212 PRO C CD  1 
ATOM   4964 N N   . ASP C 1 213 ? 112.494 127.555 160.274 1.00 73.44  ? 213 ASP C N   1 
ATOM   4965 C CA  . ASP C 1 213 ? 112.242 126.321 159.521 1.00 73.44  ? 213 ASP C CA  1 
ATOM   4966 C C   . ASP C 1 213 ? 113.531 125.667 159.020 1.00 73.44  ? 213 ASP C C   1 
ATOM   4967 O O   . ASP C 1 213 ? 113.739 125.472 157.827 1.00 73.44  ? 213 ASP C O   1 
ATOM   4968 C CB  . ASP C 1 213 ? 111.313 126.590 158.338 1.00 73.44  ? 213 ASP C CB  1 
ATOM   4969 C CG  . ASP C 1 213 ? 109.867 126.445 158.697 1.00 73.44  ? 213 ASP C CG  1 
ATOM   4970 O OD1 . ASP C 1 213 ? 109.575 125.817 159.734 1.00 73.44  ? 213 ASP C OD1 1 
ATOM   4971 O OD2 . ASP C 1 213 ? 109.023 126.963 157.941 1.00 73.44  ? 213 ASP C OD2 1 
ATOM   4972 N N   . PHE C 1 214 ? 114.405 125.347 159.964 1.00 67.02  ? 214 PHE C N   1 
ATOM   4973 C CA  . PHE C 1 214 ? 115.663 124.727 159.587 1.00 67.02  ? 214 PHE C CA  1 
ATOM   4974 C C   . PHE C 1 214 ? 115.487 123.311 159.070 1.00 67.02  ? 214 PHE C C   1 
ATOM   4975 O O   . PHE C 1 214 ? 116.375 122.808 158.380 1.00 67.02  ? 214 PHE C O   1 
ATOM   4976 C CB  . PHE C 1 214 ? 116.622 124.713 160.769 1.00 67.02  ? 214 PHE C CB  1 
ATOM   4977 C CG  . PHE C 1 214 ? 117.039 126.069 161.221 1.00 67.02  ? 214 PHE C CG  1 
ATOM   4978 C CD1 . PHE C 1 214 ? 117.946 126.801 160.496 1.00 67.02  ? 214 PHE C CD1 1 
ATOM   4979 C CD2 . PHE C 1 214 ? 116.525 126.610 162.373 1.00 67.02  ? 214 PHE C CD2 1 
ATOM   4980 C CE1 . PHE C 1 214 ? 118.330 128.039 160.911 1.00 67.02  ? 214 PHE C CE1 1 
ATOM   4981 C CE2 . PHE C 1 214 ? 116.908 127.851 162.789 1.00 67.02  ? 214 PHE C CE2 1 
ATOM   4982 C CZ  . PHE C 1 214 ? 117.811 128.565 162.057 1.00 67.02  ? 214 PHE C CZ  1 
ATOM   4983 N N   . THR C 1 215 ? 114.370 122.662 159.379 1.00 69.36  ? 215 THR C N   1 
ATOM   4984 C CA  . THR C 1 215 ? 114.166 121.261 159.049 1.00 69.36  ? 215 THR C CA  1 
ATOM   4985 C C   . THR C 1 215 ? 112.870 121.097 158.274 1.00 69.36  ? 215 THR C C   1 
ATOM   4986 O O   . THR C 1 215 ? 111.863 121.725 158.608 1.00 69.36  ? 215 THR C O   1 
ATOM   4987 C CB  . THR C 1 215 ? 114.127 120.401 160.307 1.00 69.36  ? 215 THR C CB  1 
ATOM   4988 O OG1 . THR C 1 215 ? 113.108 120.892 161.184 1.00 69.36  ? 215 THR C OG1 1 
ATOM   4989 C CG2 . THR C 1 215 ? 115.453 120.453 161.015 1.00 69.36  ? 215 THR C CG2 1 
ATOM   4990 N N   . ASN C 1 216 ? 112.899 120.250 157.256 1.00 66.53  ? 216 ASN C N   1 
ATOM   4991 C CA  . ASN C 1 216 ? 111.728 119.949 156.448 1.00 66.53  ? 216 ASN C CA  1 
ATOM   4992 C C   . ASN C 1 216 ? 111.311 118.501 156.652 1.00 66.53  ? 216 ASN C C   1 
ATOM   4993 O O   . ASN C 1 216 ? 112.146 117.664 157.006 1.00 66.53  ? 216 ASN C O   1 
ATOM   4994 C CB  . ASN C 1 216 ? 112.028 120.202 154.976 1.00 66.53  ? 216 ASN C CB  1 
ATOM   4995 C CG  . ASN C 1 216 ? 112.847 121.436 154.765 1.00 66.53  ? 216 ASN C CG  1 
ATOM   4996 O OD1 . ASN C 1 216 ? 112.391 122.541 155.033 1.00 66.53  ? 216 ASN C OD1 1 
ATOM   4997 N ND2 . ASN C 1 216 ? 114.072 121.263 154.296 1.00 66.53  ? 216 ASN C ND2 1 
ATOM   4998 N N   . PRO C 1 217 ? 110.047 118.164 156.441 1.00 65.76  ? 217 PRO C N   1 
ATOM   4999 C CA  . PRO C 1 217 ? 109.653 116.752 156.473 1.00 65.76  ? 217 PRO C CA  1 
ATOM   5000 C C   . PRO C 1 217 ? 110.312 115.969 155.354 1.00 65.76  ? 217 PRO C C   1 
ATOM   5001 O O   . PRO C 1 217 ? 111.028 116.542 154.534 1.00 65.76  ? 217 PRO C O   1 
ATOM   5002 C CB  . PRO C 1 217 ? 108.135 116.811 156.298 1.00 65.76  ? 217 PRO C CB  1 
ATOM   5003 C CG  . PRO C 1 217 ? 107.760 118.152 156.767 1.00 65.76  ? 217 PRO C CG  1 
ATOM   5004 C CD  . PRO C 1 217 ? 108.881 119.052 156.383 1.00 65.76  ? 217 PRO C CD  1 
ATOM   5005 N N   . PHE C 1 218 ? 110.079 114.661 155.296 1.00 68.50  ? 218 PHE C N   1 
ATOM   5006 C CA  . PHE C 1 218 ? 110.698 113.855 154.255 1.00 68.50  ? 218 PHE C CA  1 
ATOM   5007 C C   . PHE C 1 218 ? 110.135 114.228 152.896 1.00 68.50  ? 218 PHE C C   1 
ATOM   5008 O O   . PHE C 1 218 ? 110.884 114.639 152.006 1.00 68.50  ? 218 PHE C O   1 
ATOM   5009 C CB  . PHE C 1 218 ? 110.480 112.370 154.513 1.00 68.50  ? 218 PHE C CB  1 
ATOM   5010 C CG  . PHE C 1 218 ? 111.002 111.482 153.425 1.00 68.50  ? 218 PHE C CG  1 
ATOM   5011 C CD1 . PHE C 1 218 ? 112.340 111.151 153.371 1.00 68.50  ? 218 PHE C CD1 1 
ATOM   5012 C CD2 . PHE C 1 218 ? 110.160 110.977 152.459 1.00 68.50  ? 218 PHE C CD2 1 
ATOM   5013 C CE1 . PHE C 1 218 ? 112.822 110.332 152.384 1.00 68.50  ? 218 PHE C CE1 1 
ATOM   5014 C CE2 . PHE C 1 218 ? 110.642 110.163 151.467 1.00 68.50  ? 218 PHE C CE2 1 
ATOM   5015 C CZ  . PHE C 1 218 ? 111.975 109.842 151.432 1.00 68.50  ? 218 PHE C CZ  1 
ATOM   5016 N N   . LEU C 1 219 ? 108.818 114.098 152.729 1.00 73.72  ? 219 LEU C N   1 
ATOM   5017 C CA  . LEU C 1 219 ? 108.202 114.378 151.438 1.00 73.72  ? 219 LEU C CA  1 
ATOM   5018 C C   . LEU C 1 219 ? 108.504 115.788 150.979 1.00 73.72  ? 219 LEU C C   1 
ATOM   5019 O O   . LEU C 1 219 ? 108.722 116.035 149.792 1.00 73.72  ? 219 LEU C O   1 
ATOM   5020 C CB  . LEU C 1 219 ? 106.691 114.171 151.501 1.00 73.72  ? 219 LEU C CB  1 
ATOM   5021 C CG  . LEU C 1 219 ? 106.197 112.731 151.420 1.00 73.72  ? 219 LEU C CG  1 
ATOM   5022 C CD1 . LEU C 1 219 ? 104.686 112.708 151.284 1.00 73.72  ? 219 LEU C CD1 1 
ATOM   5023 C CD2 . LEU C 1 219 ? 106.854 112.009 150.263 1.00 73.72  ? 219 LEU C CD2 1 
ATOM   5024 N N   . PHE C 1 220 ? 108.463 116.724 151.922 1.00 67.20  ? 220 PHE C N   1 
ATOM   5025 C CA  . PHE C 1 220 ? 108.713 118.129 151.626 1.00 67.20  ? 220 PHE C CA  1 
ATOM   5026 C C   . PHE C 1 220 ? 110.088 118.328 151.006 1.00 67.20  ? 220 PHE C C   1 
ATOM   5027 O O   . PHE C 1 220 ? 110.219 118.918 149.934 1.00 67.20  ? 220 PHE C O   1 
ATOM   5028 C CB  . PHE C 1 220 ? 108.582 118.975 152.895 1.00 67.20  ? 220 PHE C CB  1 
ATOM   5029 C CG  . PHE C 1 220 ? 108.033 120.351 152.652 1.00 67.20  ? 220 PHE C CG  1 
ATOM   5030 C CD1 . PHE C 1 220 ? 106.873 120.770 153.283 1.00 67.20  ? 220 PHE C CD1 1 
ATOM   5031 C CD2 . PHE C 1 220 ? 108.675 121.226 151.793 1.00 67.20  ? 220 PHE C CD2 1 
ATOM   5032 C CE1 . PHE C 1 220 ? 106.365 122.036 153.062 1.00 67.20  ? 220 PHE C CE1 1 
ATOM   5033 C CE2 . PHE C 1 220 ? 108.172 122.494 151.567 1.00 67.20  ? 220 PHE C CE2 1 
ATOM   5034 C CZ  . PHE C 1 220 ? 107.015 122.899 152.203 1.00 67.20  ? 220 PHE C CZ  1 
ATOM   5035 N N   . LYS C 1 221 ? 111.112 117.830 151.688 1.00 62.19  ? 221 LYS C N   1 
ATOM   5036 C CA  . LYS C 1 221 ? 112.482 117.956 151.200 1.00 62.19  ? 221 LYS C CA  1 
ATOM   5037 C C   . LYS C 1 221 ? 112.670 117.229 149.881 1.00 62.19  ? 221 LYS C C   1 
ATOM   5038 O O   . LYS C 1 221 ? 113.343 117.736 148.978 1.00 62.19  ? 221 LYS C O   1 
ATOM   5039 C CB  . LYS C 1 221 ? 113.464 117.410 152.228 1.00 62.19  ? 221 LYS C CB  1 
ATOM   5040 C CG  . LYS C 1 221 ? 114.924 117.561 151.846 1.00 62.19  ? 221 LYS C CG  1 
ATOM   5041 C CD  . LYS C 1 221 ? 115.801 117.017 152.946 1.00 62.19  ? 221 LYS C CD  1 
ATOM   5042 C CE  . LYS C 1 221 ? 117.268 117.019 152.599 1.00 62.19  ? 221 LYS C CE  1 
ATOM   5043 N NZ  . LYS C 1 221 ? 117.808 118.387 152.505 1.00 62.19  ? 221 LYS C NZ  1 
ATOM   5044 N N   . VAL C 1 222 ? 112.108 116.025 149.759 1.00 64.58  ? 222 VAL C N   1 
ATOM   5045 C CA  . VAL C 1 222 ? 112.262 115.264 148.524 1.00 64.58  ? 222 VAL C CA  1 
ATOM   5046 C C   . VAL C 1 222 ? 111.641 116.001 147.357 1.00 64.58  ? 222 VAL C C   1 
ATOM   5047 O O   . VAL C 1 222 ? 112.250 116.108 146.293 1.00 64.58  ? 222 VAL C O   1 
ATOM   5048 C CB  . VAL C 1 222 ? 111.660 113.860 148.670 1.00 64.58  ? 222 VAL C CB  1 
ATOM   5049 C CG1 . VAL C 1 222 ? 111.489 113.238 147.317 1.00 64.58  ? 222 VAL C CG1 1 
ATOM   5050 C CG2 . VAL C 1 222 ? 112.566 113.004 149.501 1.00 64.58  ? 222 VAL C CG2 1 
ATOM   5051 N N   . PHE C 1 223 ? 110.435 116.530 147.530 1.00 67.19  ? 223 PHE C N   1 
ATOM   5052 C CA  . PHE C 1 223 ? 109.806 117.311 146.479 1.00 67.19  ? 223 PHE C CA  1 
ATOM   5053 C C   . PHE C 1 223 ? 110.608 118.552 146.149 1.00 67.19  ? 223 PHE C C   1 
ATOM   5054 O O   . PHE C 1 223 ? 110.758 118.894 144.971 1.00 67.19  ? 223 PHE C O   1 
ATOM   5055 C CB  . PHE C 1 223 ? 108.397 117.704 146.899 1.00 67.19  ? 223 PHE C CB  1 
ATOM   5056 C CG  . PHE C 1 223 ? 107.789 118.770 146.052 1.00 67.19  ? 223 PHE C CG  1 
ATOM   5057 C CD1 . PHE C 1 223 ? 107.247 118.465 144.826 1.00 67.19  ? 223 PHE C CD1 1 
ATOM   5058 C CD2 . PHE C 1 223 ? 107.731 120.075 146.492 1.00 67.19  ? 223 PHE C CD2 1 
ATOM   5059 C CE1 . PHE C 1 223 ? 106.679 119.435 144.049 1.00 67.19  ? 223 PHE C CE1 1 
ATOM   5060 C CE2 . PHE C 1 223 ? 107.163 121.049 145.715 1.00 67.19  ? 223 PHE C CE2 1 
ATOM   5061 C CZ  . PHE C 1 223 ? 106.637 120.728 144.494 1.00 67.19  ? 223 PHE C CZ  1 
ATOM   5062 N N   . TYR C 1 224 ? 111.140 119.225 147.161 1.00 61.64  ? 224 TYR C N   1 
ATOM   5063 C CA  . TYR C 1 224 ? 111.797 120.495 146.910 1.00 61.64  ? 224 TYR C CA  1 
ATOM   5064 C C   . TYR C 1 224 ? 113.088 120.274 146.134 1.00 61.64  ? 224 TYR C C   1 
ATOM   5065 O O   . TYR C 1 224 ? 113.350 120.948 145.131 1.00 61.64  ? 224 TYR C O   1 
ATOM   5066 C CB  . TYR C 1 224 ? 112.087 121.175 148.236 1.00 61.64  ? 224 TYR C CB  1 
ATOM   5067 C CG  . TYR C 1 224 ? 112.054 122.661 148.170 1.00 61.64  ? 224 TYR C CG  1 
ATOM   5068 C CD1 . TYR C 1 224 ? 110.859 123.327 148.340 1.00 61.64  ? 224 TYR C CD1 1 
ATOM   5069 C CD2 . TYR C 1 224 ? 113.173 123.395 147.866 1.00 61.64  ? 224 TYR C CD2 1 
ATOM   5070 C CE1 . TYR C 1 224 ? 110.789 124.671 148.278 1.00 61.64  ? 224 TYR C CE1 1 
ATOM   5071 C CE2 . TYR C 1 224 ? 113.108 124.756 147.789 1.00 61.64  ? 224 TYR C CE2 1 
ATOM   5072 C CZ  . TYR C 1 224 ? 111.910 125.384 147.997 1.00 61.64  ? 224 TYR C CZ  1 
ATOM   5073 O OH  . TYR C 1 224 ? 111.819 126.744 147.924 1.00 61.64  ? 224 TYR C OH  1 
ATOM   5074 N N   . LEU C 1 225 ? 113.882 119.290 146.551 1.00 64.02  ? 225 LEU C N   1 
ATOM   5075 C CA  . LEU C 1 225 ? 115.107 118.963 145.835 1.00 64.02  ? 225 LEU C CA  1 
ATOM   5076 C C   . LEU C 1 225 ? 114.852 118.268 144.505 1.00 64.02  ? 225 LEU C C   1 
ATOM   5077 O O   . LEU C 1 225 ? 115.666 118.401 143.595 1.00 64.02  ? 225 LEU C O   1 
ATOM   5078 C CB  . LEU C 1 225 ? 116.013 118.098 146.703 1.00 64.02  ? 225 LEU C CB  1 
ATOM   5079 C CG  . LEU C 1 225 ? 116.680 118.812 147.872 1.00 64.02  ? 225 LEU C CG  1 
ATOM   5080 C CD1 . LEU C 1 225 ? 117.789 117.962 148.415 1.00 64.02  ? 225 LEU C CD1 1 
ATOM   5081 C CD2 . LEU C 1 225 ? 117.218 120.132 147.411 1.00 64.02  ? 225 LEU C CD2 1 
ATOM   5082 N N   . GLY C 1 226 ? 113.748 117.540 144.355 1.00 66.16  ? 226 GLY C N   1 
ATOM   5083 C CA  . GLY C 1 226 ? 113.402 117.022 143.046 1.00 66.16  ? 226 GLY C CA  1 
ATOM   5084 C C   . GLY C 1 226 ? 113.112 118.132 142.057 1.00 66.16  ? 226 GLY C C   1 
ATOM   5085 O O   . GLY C 1 226 ? 113.586 118.103 140.921 1.00 66.16  ? 226 GLY C O   1 
ATOM   5086 N N   . GLN C 1 227 ? 112.332 119.130 142.473 1.00 72.07  ? 227 GLN C N   1 
ATOM   5087 C CA  . GLN C 1 227 ? 112.136 120.293 141.617 1.00 72.07  ? 227 GLN C CA  1 
ATOM   5088 C C   . GLN C 1 227 ? 113.457 120.975 141.309 1.00 72.07  ? 227 GLN C C   1 
ATOM   5089 O O   . GLN C 1 227 ? 113.699 121.386 140.169 1.00 72.07  ? 227 GLN C O   1 
ATOM   5090 C CB  . GLN C 1 227 ? 111.174 121.282 142.269 1.00 72.07  ? 227 GLN C CB  1 
ATOM   5091 C CG  . GLN C 1 227 ? 109.750 120.815 142.321 1.00 72.07  ? 227 GLN C CG  1 
ATOM   5092 C CD  . GLN C 1 227 ? 109.153 120.678 140.946 1.00 72.07  ? 227 GLN C CD  1 
ATOM   5093 O OE1 . GLN C 1 227 ? 108.920 119.573 140.467 1.00 72.07  ? 227 GLN C OE1 1 
ATOM   5094 N NE2 . GLN C 1 227 ? 108.896 121.804 140.300 1.00 72.07  ? 227 GLN C NE2 1 
ATOM   5095 N N   . ALA C 1 228 ? 114.318 121.118 142.314 1.00 68.90  ? 228 ALA C N   1 
ATOM   5096 C CA  . ALA C 1 228 ? 115.616 121.740 142.075 1.00 68.90  ? 228 ALA C CA  1 
ATOM   5097 C C   . ALA C 1 228 ? 116.398 120.984 141.011 1.00 68.90  ? 228 ALA C C   1 
ATOM   5098 O O   . ALA C 1 228 ? 116.925 121.583 140.069 1.00 68.90  ? 228 ALA C O   1 
ATOM   5099 C CB  . ALA C 1 228 ? 116.413 121.814 143.373 1.00 68.90  ? 228 ALA C CB  1 
ATOM   5100 N N   . ALA C 1 229 ? 116.468 119.659 141.137 1.00 71.37  ? 229 ALA C N   1 
ATOM   5101 C CA  . ALA C 1 229 ? 117.220 118.851 140.188 1.00 71.37  ? 229 ALA C CA  1 
ATOM   5102 C C   . ALA C 1 229 ? 116.619 118.928 138.794 1.00 71.37  ? 229 ALA C C   1 
ATOM   5103 O O   . ALA C 1 229 ? 117.338 119.072 137.803 1.00 71.37  ? 229 ALA C O   1 
ATOM   5104 C CB  . ALA C 1 229 ? 117.270 117.404 140.663 1.00 71.37  ? 229 ALA C CB  1 
ATOM   5105 N N   . PHE C 1 230 ? 115.294 118.841 138.701 1.00 76.67  ? 230 PHE C N   1 
ATOM   5106 C CA  . PHE C 1 230 ? 114.640 118.861 137.399 1.00 76.67  ? 230 PHE C CA  1 
ATOM   5107 C C   . PHE C 1 230 ? 114.883 120.177 136.677 1.00 76.67  ? 230 PHE C C   1 
ATOM   5108 O O   . PHE C 1 230 ? 115.237 120.191 135.495 1.00 76.67  ? 230 PHE C O   1 
ATOM   5109 C CB  . PHE C 1 230 ? 113.147 118.617 137.567 1.00 76.67  ? 230 PHE C CB  1 
ATOM   5110 C CG  . PHE C 1 230 ? 112.380 118.732 136.301 1.00 76.67  ? 230 PHE C CG  1 
ATOM   5111 C CD1 . PHE C 1 230 ? 112.363 117.695 135.398 1.00 76.67  ? 230 PHE C CD1 1 
ATOM   5112 C CD2 . PHE C 1 230 ? 111.669 119.871 136.012 1.00 76.67  ? 230 PHE C CD2 1 
ATOM   5113 C CE1 . PHE C 1 230 ? 111.657 117.794 134.230 1.00 76.67  ? 230 PHE C CE1 1 
ATOM   5114 C CE2 . PHE C 1 230 ? 110.960 119.974 134.843 1.00 76.67  ? 230 PHE C CE2 1 
ATOM   5115 C CZ  . PHE C 1 230 ? 110.956 118.933 133.952 1.00 76.67  ? 230 PHE C CZ  1 
ATOM   5116 N N   . TRP C 1 231 ? 114.700 121.300 137.368 1.00 78.01  ? 231 TRP C N   1 
ATOM   5117 C CA  . TRP C 1 231 ? 114.881 122.574 136.687 1.00 78.01  ? 231 TRP C CA  1 
ATOM   5118 C C   . TRP C 1 231 ? 116.348 122.871 136.415 1.00 78.01  ? 231 TRP C C   1 
ATOM   5119 O O   . TRP C 1 231 ? 116.670 123.493 135.396 1.00 78.01  ? 231 TRP C O   1 
ATOM   5120 C CB  . TRP C 1 231 ? 114.235 123.699 137.484 1.00 78.01  ? 231 TRP C CB  1 
ATOM   5121 C CG  . TRP C 1 231 ? 112.757 123.654 137.446 1.00 78.01  ? 231 TRP C CG  1 
ATOM   5122 C CD1 . TRP C 1 231 ? 111.925 123.517 138.504 1.00 78.01  ? 231 TRP C CD1 1 
ATOM   5123 C CD2 . TRP C 1 231 ? 111.927 123.721 136.287 1.00 78.01  ? 231 TRP C CD2 1 
ATOM   5124 N NE1 . TRP C 1 231 ? 110.623 123.505 138.085 1.00 78.01  ? 231 TRP C NE1 1 
ATOM   5125 C CE2 . TRP C 1 231 ? 110.600 123.625 136.723 1.00 78.01  ? 231 TRP C CE2 1 
ATOM   5126 C CE3 . TRP C 1 231 ? 112.177 123.854 134.923 1.00 78.01  ? 231 TRP C CE3 1 
ATOM   5127 C CZ2 . TRP C 1 231 ? 109.525 123.656 135.847 1.00 78.01  ? 231 TRP C CZ2 1 
ATOM   5128 C CZ3 . TRP C 1 231 ? 111.111 123.885 134.057 1.00 78.01  ? 231 TRP C CZ3 1 
ATOM   5129 C CH2 . TRP C 1 231 ? 109.801 123.789 134.520 1.00 78.01  ? 231 TRP C CH2 1 
ATOM   5130 N N   . ALA C 1 232 ? 117.254 122.427 137.283 1.00 78.55  ? 232 ALA C N   1 
ATOM   5131 C CA  . ALA C 1 232 ? 118.671 122.567 136.975 1.00 78.55  ? 232 ALA C CA  1 
ATOM   5132 C C   . ALA C 1 232 ? 119.027 121.781 135.725 1.00 78.55  ? 232 ALA C C   1 
ATOM   5133 O O   . ALA C 1 232 ? 119.791 122.253 134.878 1.00 78.55  ? 232 ALA C O   1 
ATOM   5134 C CB  . ALA C 1 232 ? 119.517 122.109 138.158 1.00 78.55  ? 232 ALA C CB  1 
ATOM   5135 N N   . GLN C 1 233 ? 118.477 120.580 135.585 1.00 79.89  ? 233 GLN C N   1 
ATOM   5136 C CA  . GLN C 1 233 ? 118.702 119.801 134.378 1.00 79.89  ? 233 GLN C CA  1 
ATOM   5137 C C   . GLN C 1 233 ? 118.090 120.442 133.144 1.00 79.89  ? 233 GLN C C   1 
ATOM   5138 O O   . GLN C 1 233 ? 118.675 120.360 132.060 1.00 79.89  ? 233 GLN C O   1 
ATOM   5139 C CB  . GLN C 1 233 ? 118.141 118.403 134.561 1.00 79.89  ? 233 GLN C CB  1 
ATOM   5140 C CG  . GLN C 1 233 ? 118.674 117.429 133.584 1.00 79.89  ? 233 GLN C CG  1 
ATOM   5141 C CD  . GLN C 1 233 ? 117.660 117.102 132.538 1.00 79.89  ? 233 GLN C CD  1 
ATOM   5142 O OE1 . GLN C 1 233 ? 116.470 117.340 132.721 1.00 79.89  ? 233 GLN C OE1 1 
ATOM   5143 N NE2 . GLN C 1 233 ? 118.120 116.562 131.421 1.00 79.89  ? 233 GLN C NE2 1 
ATOM   5144 N N   . GLN C 1 234 ? 116.923 121.065 133.274 1.00 84.45  ? 234 GLN C N   1 
ATOM   5145 C CA  . GLN C 1 234 ? 116.359 121.788 132.143 1.00 84.45  ? 234 GLN C CA  1 
ATOM   5146 C C   . GLN C 1 234 ? 117.285 122.913 131.707 1.00 84.45  ? 234 GLN C C   1 
ATOM   5147 O O   . GLN C 1 234 ? 117.536 123.097 130.513 1.00 84.45  ? 234 GLN C O   1 
ATOM   5148 C CB  . GLN C 1 234 ? 114.986 122.344 132.503 1.00 84.45  ? 234 GLN C CB  1 
ATOM   5149 C CG  . GLN C 1 234 ? 113.915 121.298 132.620 1.00 84.45  ? 234 GLN C CG  1 
ATOM   5150 C CD  . GLN C 1 234 ? 113.412 120.815 131.290 1.00 84.45  ? 234 GLN C CD  1 
ATOM   5151 O OE1 . GLN C 1 234 ? 114.160 120.723 130.320 1.00 84.45  ? 234 GLN C OE1 1 
ATOM   5152 N NE2 . GLN C 1 234 ? 112.129 120.498 131.232 1.00 84.45  ? 234 GLN C NE2 1 
ATOM   5153 N N   . ALA C 1 235 ? 117.812 123.672 132.666 1.00 85.91  ? 235 ALA C N   1 
ATOM   5154 C CA  . ALA C 1 235 ? 118.750 124.736 132.319 1.00 85.91  ? 235 ALA C CA  1 
ATOM   5155 C C   . ALA C 1 235 ? 120.009 124.168 131.679 1.00 85.91  ? 235 ALA C C   1 
ATOM   5156 O O   . ALA C 1 235 ? 120.564 124.758 130.744 1.00 85.91  ? 235 ALA C O   1 
ATOM   5157 C CB  . ALA C 1 235 ? 119.100 125.556 133.558 1.00 85.91  ? 235 ALA C CB  1 
ATOM   5158 N N   . CYS C 1 236 ? 120.484 123.029 132.180 1.00 90.32  ? 236 CYS C N   1 
ATOM   5159 C CA  . CYS C 1 236 ? 121.670 122.401 131.612 1.00 90.32  ? 236 CYS C CA  1 
ATOM   5160 C C   . CYS C 1 236 ? 121.439 121.996 130.164 1.00 90.32  ? 236 CYS C C   1 
ATOM   5161 O O   . CYS C 1 236 ? 122.315 122.189 129.316 1.00 90.32  ? 236 CYS C O   1 
ATOM   5162 C CB  . CYS C 1 236 ? 122.071 121.192 132.458 1.00 90.32  ? 236 CYS C CB  1 
ATOM   5163 S SG  . CYS C 1 236 ? 123.422 120.194 131.804 1.00 90.32  ? 236 CYS C SG  1 
ATOM   5164 N N   . ILE C 1 237 ? 120.274 121.433 129.860 1.00 92.39  ? 237 ILE C N   1 
ATOM   5165 C CA  . ILE C 1 237 ? 119.947 121.078 128.483 1.00 92.39  ? 237 ILE C CA  1 
ATOM   5166 C C   . ILE C 1 237 ? 119.837 122.333 127.635 1.00 92.39  ? 237 ILE C C   1 
ATOM   5167 O O   . ILE C 1 237 ? 120.262 122.350 126.477 1.00 92.39  ? 237 ILE C O   1 
ATOM   5168 C CB  . ILE C 1 237 ? 118.659 120.244 128.403 1.00 92.39  ? 237 ILE C CB  1 
ATOM   5169 C CG1 . ILE C 1 237 ? 118.833 118.947 129.175 1.00 92.39  ? 237 ILE C CG1 1 
ATOM   5170 C CG2 . ILE C 1 237 ? 118.303 119.955 126.970 1.00 92.39  ? 237 ILE C CG2 1 
ATOM   5171 C CD1 . ILE C 1 237 ? 119.943 118.093 128.625 1.00 92.39  ? 237 ILE C CD1 1 
ATOM   5172 N N   . LEU C 1 238 ? 119.283 123.397 128.204 1.00 95.40  ? 238 LEU C N   1 
ATOM   5173 C CA  . LEU C 1 238 ? 119.104 124.631 127.450 1.00 95.40  ? 238 LEU C CA  1 
ATOM   5174 C C   . LEU C 1 238 ? 120.438 125.250 127.041 1.00 95.40  ? 238 LEU C C   1 
ATOM   5175 O O   . LEU C 1 238 ? 120.697 125.437 125.849 1.00 95.40  ? 238 LEU C O   1 
ATOM   5176 C CB  . LEU C 1 238 ? 118.266 125.615 128.270 1.00 95.40  ? 238 LEU C CB  1 
ATOM   5177 C CG  . LEU C 1 238 ? 117.985 126.994 127.691 1.00 95.40  ? 238 LEU C CG  1 
ATOM   5178 C CD1 . LEU C 1 238 ? 116.620 127.439 128.145 1.00 95.40  ? 238 LEU C CD1 1 
ATOM   5179 C CD2 . LEU C 1 238 ? 119.032 127.972 128.160 1.00 95.40  ? 238 LEU C CD2 1 
ATOM   5180 N N   . VAL C 1 239 ? 121.296 125.571 128.015 1.00 98.56  ? 239 VAL C N   1 
ATOM   5181 C CA  . VAL C 1 239 ? 122.532 126.284 127.690 1.00 98.56  ? 239 VAL C CA  1 
ATOM   5182 C C   . VAL C 1 239 ? 123.470 125.413 126.869 1.00 98.56  ? 239 VAL C C   1 
ATOM   5183 O O   . VAL C 1 239 ? 124.175 125.914 125.988 1.00 98.56  ? 239 VAL C O   1 
ATOM   5184 C CB  . VAL C 1 239 ? 123.225 126.810 128.963 1.00 98.56  ? 239 VAL C CB  1 
ATOM   5185 C CG1 . VAL C 1 239 ? 122.336 127.806 129.681 1.00 98.56  ? 239 VAL C CG1 1 
ATOM   5186 C CG2 . VAL C 1 239 ? 123.613 125.676 129.883 1.00 98.56  ? 239 VAL C CG2 1 
ATOM   5187 N N   . LEU C 1 240 ? 123.507 124.112 127.139 1.00 101.41 ? 240 LEU C N   1 
ATOM   5188 C CA  . LEU C 1 240 ? 124.259 123.174 126.310 1.00 101.41 ? 240 LEU C CA  1 
ATOM   5189 C C   . LEU C 1 240 ? 123.429 122.941 125.058 1.00 101.41 ? 240 LEU C C   1 
ATOM   5190 O O   . LEU C 1 240 ? 122.608 122.026 125.004 1.00 101.41 ? 240 LEU C O   1 
ATOM   5191 C CB  . LEU C 1 240 ? 124.540 121.877 127.061 1.00 101.41 ? 240 LEU C CB  1 
ATOM   5192 C CG  . LEU C 1 240 ? 125.257 120.739 126.327 1.00 101.41 ? 240 LEU C CG  1 
ATOM   5193 C CD1 . LEU C 1 240 ? 126.343 120.142 127.186 1.00 101.41 ? 240 LEU C CD1 1 
ATOM   5194 C CD2 . LEU C 1 240 ? 124.282 119.653 125.936 1.00 101.41 ? 240 LEU C CD2 1 
ATOM   5195 N N   . GLN C 1 241 ? 123.627 123.787 124.053 1.00 111.28 ? 241 GLN C N   1 
ATOM   5196 C CA  . GLN C 1 241 ? 122.840 123.693 122.830 1.00 111.28 ? 241 GLN C CA  1 
ATOM   5197 C C   . GLN C 1 241 ? 123.173 122.397 122.111 1.00 111.28 ? 241 GLN C C   1 
ATOM   5198 O O   . GLN C 1 241 ? 124.221 122.281 121.469 1.00 111.28 ? 241 GLN C O   1 
ATOM   5199 C CB  . GLN C 1 241 ? 123.107 124.894 121.932 1.00 111.28 ? 241 GLN C CB  1 
ATOM   5200 C CG  . GLN C 1 241 ? 122.894 126.249 122.582 1.00 111.28 ? 241 GLN C CG  1 
ATOM   5201 C CD  . GLN C 1 241 ? 121.441 126.557 122.894 1.00 111.28 ? 241 GLN C CD  1 
ATOM   5202 O OE1 . GLN C 1 241 ? 120.597 125.666 123.000 1.00 111.28 ? 241 GLN C OE1 1 
ATOM   5203 N NE2 . GLN C 1 241 ? 121.142 127.837 123.030 1.00 111.28 ? 241 GLN C NE2 1 
ATOM   5204 N N   . LEU C 1 242 ? 122.284 121.417 122.217 1.00 119.03 ? 242 LEU C N   1 
ATOM   5205 C CA  . LEU C 1 242 ? 122.428 120.205 121.431 1.00 119.03 ? 242 LEU C CA  1 
ATOM   5206 C C   . LEU C 1 242 ? 121.828 120.492 120.062 1.00 119.03 ? 242 LEU C C   1 
ATOM   5207 O O   . LEU C 1 242 ? 122.477 120.291 119.033 1.00 119.03 ? 242 LEU C O   1 
ATOM   5208 C CB  . LEU C 1 242 ? 121.746 119.023 122.124 1.00 119.03 ? 242 LEU C CB  1 
ATOM   5209 C CG  . LEU C 1 242 ? 122.209 117.621 121.735 1.00 119.03 ? 242 LEU C CG  1 
ATOM   5210 C CD1 . LEU C 1 242 ? 123.643 117.406 122.187 1.00 119.03 ? 242 LEU C CD1 1 
ATOM   5211 C CD2 . LEU C 1 242 ? 121.292 116.561 122.326 1.00 119.03 ? 242 LEU C CD2 1 
ATOM   5212 N N   . GLU C 1 243 ? 120.592 120.988 120.056 1.00 125.23 ? 243 GLU C N   1 
ATOM   5213 C CA  . GLU C 1 243 ? 119.950 121.552 118.873 1.00 125.23 ? 243 GLU C CA  1 
ATOM   5214 C C   . GLU C 1 243 ? 119.199 122.801 119.309 1.00 125.23 ? 243 GLU C C   1 
ATOM   5215 O O   . GLU C 1 243 ? 118.562 122.801 120.368 1.00 125.23 ? 243 GLU C O   1 
ATOM   5216 C CB  . GLU C 1 243 ? 119.000 120.548 118.218 1.00 125.23 ? 243 GLU C CB  1 
ATOM   5217 C CG  . GLU C 1 243 ? 119.618 119.742 117.085 1.00 125.23 ? 243 GLU C CG  1 
ATOM   5218 C CD  . GLU C 1 243 ? 120.541 118.648 117.581 1.00 125.23 ? 243 GLU C CD  1 
ATOM   5219 O OE1 . GLU C 1 243 ? 121.512 118.317 116.872 1.00 125.23 ? 243 GLU C OE1 1 
ATOM   5220 O OE2 . GLU C 1 243 ? 120.300 118.126 118.689 1.00 125.23 ? 243 GLU C OE2 1 
ATOM   5221 N N   . LYS C 1 244 ? 119.304 123.878 118.539 1.00 127.15 ? 244 LYS C N   1 
ATOM   5222 C CA  . LYS C 1 244 ? 118.648 125.129 118.906 1.00 127.15 ? 244 LYS C CA  1 
ATOM   5223 C C   . LYS C 1 244 ? 117.219 125.237 118.391 1.00 127.15 ? 244 LYS C C   1 
ATOM   5224 O O   . LYS C 1 244 ? 116.995 125.281 117.181 1.00 127.15 ? 244 LYS C O   1 
ATOM   5225 C CB  . LYS C 1 244 ? 119.470 126.325 118.415 1.00 127.15 ? 244 LYS C CB  1 
ATOM   5226 C CG  . LYS C 1 244 ? 119.003 127.665 118.961 1.00 127.15 ? 244 LYS C CG  1 
ATOM   5227 C CD  . LYS C 1 244 ? 119.365 128.801 118.018 1.00 127.15 ? 244 LYS C CD  1 
ATOM   5228 C CE  . LYS C 1 244 ? 118.294 129.880 118.018 1.00 127.15 ? 244 LYS C CE  1 
ATOM   5229 N NZ  . LYS C 1 244 ? 118.302 130.671 119.279 1.00 127.15 ? 244 LYS C NZ  1 
ATOM   5230 N N   . PRO C 1 245 ? 116.239 125.279 119.310 1.00 130.41 ? 245 PRO C N   1 
ATOM   5231 C CA  . PRO C 1 245 ? 114.844 125.400 118.880 1.00 130.41 ? 245 PRO C CA  1 
ATOM   5232 C C   . PRO C 1 245 ? 114.482 126.820 118.481 1.00 130.41 ? 245 PRO C C   1 
ATOM   5233 O O   . PRO C 1 245 ? 115.311 127.732 118.545 1.00 130.41 ? 245 PRO C O   1 
ATOM   5234 C CB  . PRO C 1 245 ? 114.071 124.944 120.129 1.00 130.41 ? 245 PRO C CB  1 
ATOM   5235 C CG  . PRO C 1 245 ? 115.116 124.142 120.903 1.00 130.41 ? 245 PRO C CG  1 
ATOM   5236 C CD  . PRO C 1 245 ? 116.276 125.063 120.761 1.00 130.41 ? 245 PRO C CD  1 
ATOM   5237 N N   . ARG C 1 246 ? 113.232 126.966 118.053 1.00 131.90 ? 246 ARG C N   1 
ATOM   5238 C CA  . ARG C 1 246 ? 112.662 128.214 117.545 1.00 131.90 ? 246 ARG C CA  1 
ATOM   5239 C C   . ARG C 1 246 ? 112.698 129.473 118.413 1.00 131.90 ? 246 ARG C C   1 
ATOM   5240 O O   . ARG C 1 246 ? 113.538 129.634 119.298 1.00 131.90 ? 246 ARG C O   1 
ATOM   5241 C CB  . ARG C 1 246 ? 111.222 127.971 117.075 1.00 131.90 ? 246 ARG C CB  1 
ATOM   5242 C CG  . ARG C 1 246 ? 111.115 127.406 115.668 1.00 131.90 ? 246 ARG C CG  1 
ATOM   5243 C CD  . ARG C 1 246 ? 110.285 128.310 114.770 1.00 131.90 ? 246 ARG C CD  1 
ATOM   5244 N NE  . ARG C 1 246 ? 110.522 128.041 113.354 1.00 131.90 ? 246 ARG C NE  1 
ATOM   5245 C CZ  . ARG C 1 246 ? 109.603 127.560 112.522 1.00 131.90 ? 246 ARG C CZ  1 
ATOM   5246 N NH1 . ARG C 1 246 ? 108.382 127.293 112.963 1.00 131.90 ? 246 ARG C NH1 1 
ATOM   5247 N NH2 . ARG C 1 246 ? 109.906 127.347 111.249 1.00 131.90 ? 246 ARG C NH2 1 
ATOM   5248 N N   . LYS C 1 247 ? 111.747 130.353 118.115 1.00 128.69 ? 247 LYS C N   1 
ATOM   5249 C CA  . LYS C 1 247 ? 111.584 131.658 118.747 1.00 128.69 ? 247 LYS C CA  1 
ATOM   5250 C C   . LYS C 1 247 ? 111.634 131.668 120.268 1.00 128.69 ? 247 LYS C C   1 
ATOM   5251 O O   . LYS C 1 247 ? 112.297 132.530 120.854 1.00 128.69 ? 247 LYS C O   1 
ATOM   5252 C CB  . LYS C 1 247 ? 110.254 132.260 118.293 1.00 128.69 ? 247 LYS C CB  1 
ATOM   5253 C CG  . LYS C 1 247 ? 109.766 133.431 119.124 1.00 128.69 ? 247 LYS C CG  1 
ATOM   5254 C CD  . LYS C 1 247 ? 108.414 133.905 118.622 1.00 128.69 ? 247 LYS C CD  1 
ATOM   5255 C CE  . LYS C 1 247 ? 107.352 132.838 118.847 1.00 128.69 ? 247 LYS C CE  1 
ATOM   5256 N NZ  . LYS C 1 247 ? 106.009 133.255 118.361 1.00 128.69 ? 247 LYS C NZ  1 
ATOM   5257 N N   . ASP C 1 248 ? 110.949 130.729 120.922 1.00 122.12 ? 248 ASP C N   1 
ATOM   5258 C CA  . ASP C 1 248 ? 110.682 130.888 122.348 1.00 122.12 ? 248 ASP C CA  1 
ATOM   5259 C C   . ASP C 1 248 ? 111.935 130.824 123.216 1.00 122.12 ? 248 ASP C C   1 
ATOM   5260 O O   . ASP C 1 248 ? 111.829 130.990 124.435 1.00 122.12 ? 248 ASP C O   1 
ATOM   5261 C CB  . ASP C 1 248 ? 109.668 129.841 122.820 1.00 122.12 ? 248 ASP C CB  1 
ATOM   5262 C CG  . ASP C 1 248 ? 110.175 128.422 122.676 1.00 122.12 ? 248 ASP C CG  1 
ATOM   5263 O OD1 . ASP C 1 248 ? 111.274 128.222 122.120 1.00 122.12 ? 248 ASP C OD1 1 
ATOM   5264 O OD2 . ASP C 1 248 ? 109.472 127.498 123.134 1.00 122.12 ? 248 ASP C OD2 1 
ATOM   5265 N N   . HIS C 1 249 ? 113.109 130.625 122.621 1.00 117.82 ? 249 HIS C N   1 
ATOM   5266 C CA  . HIS C 1 249 ? 114.327 130.286 123.348 1.00 117.82 ? 249 HIS C CA  1 
ATOM   5267 C C   . HIS C 1 249 ? 114.638 131.180 124.545 1.00 117.82 ? 249 HIS C C   1 
ATOM   5268 O O   . HIS C 1 249 ? 114.688 130.692 125.677 1.00 117.82 ? 249 HIS C O   1 
ATOM   5269 C CB  . HIS C 1 249 ? 115.516 130.302 122.390 1.00 117.82 ? 249 HIS C CB  1 
ATOM   5270 C CG  . HIS C 1 249 ? 116.761 129.708 122.968 1.00 117.82 ? 249 HIS C CG  1 
ATOM   5271 N ND1 . HIS C 1 249 ? 117.943 130.410 123.066 1.00 117.82 ? 249 HIS C ND1 1 
ATOM   5272 C CD2 . HIS C 1 249 ? 117.012 128.478 123.474 1.00 117.82 ? 249 HIS C CD2 1 
ATOM   5273 C CE1 . HIS C 1 249 ? 118.866 129.640 123.612 1.00 117.82 ? 249 HIS C CE1 1 
ATOM   5274 N NE2 . HIS C 1 249 ? 118.327 128.462 123.866 1.00 117.82 ? 249 HIS C NE2 1 
ATOM   5275 N N   . ASN C 1 250 ? 114.838 132.482 124.322 1.00 112.27 ? 250 ASN C N   1 
ATOM   5276 C CA  . ASN C 1 250 ? 115.460 133.320 125.347 1.00 112.27 ? 250 ASN C CA  1 
ATOM   5277 C C   . ASN C 1 250 ? 114.538 133.651 126.520 1.00 112.27 ? 250 ASN C C   1 
ATOM   5278 O O   . ASN C 1 250 ? 115.003 133.683 127.665 1.00 112.27 ? 250 ASN C O   1 
ATOM   5279 C CB  . ASN C 1 250 ? 115.990 134.607 124.721 1.00 112.27 ? 250 ASN C CB  1 
ATOM   5280 C CG  . ASN C 1 250 ? 117.405 134.452 124.201 1.00 112.27 ? 250 ASN C CG  1 
ATOM   5281 O OD1 . ASN C 1 250 ? 118.131 133.546 124.612 1.00 112.27 ? 250 ASN C OD1 1 
ATOM   5282 N ND2 . ASN C 1 250 ? 117.808 135.341 123.301 1.00 112.27 ? 250 ASN C ND2 1 
ATOM   5283 N N   . GLU C 1 251 ? 113.248 133.814 126.240 1.00 109.94 ? 251 GLU C N   1 
ATOM   5284 C CA  . GLU C 1 251 ? 112.274 134.059 127.291 1.00 109.94 ? 251 GLU C CA  1 
ATOM   5285 C C   . GLU C 1 251 ? 112.250 132.801 128.151 1.00 109.94 ? 251 GLU C C   1 
ATOM   5286 O O   . GLU C 1 251 ? 112.172 132.872 129.378 1.00 109.94 ? 251 GLU C O   1 
ATOM   5287 C CB  . GLU C 1 251 ? 110.893 134.329 126.698 1.00 109.94 ? 251 GLU C CB  1 
ATOM   5288 C CG  . GLU C 1 251 ? 109.781 134.416 127.730 1.00 109.94 ? 251 GLU C CG  1 
ATOM   5289 C CD  . GLU C 1 251 ? 108.415 134.603 127.100 1.00 109.94 ? 251 GLU C CD  1 
ATOM   5290 O OE1 . GLU C 1 251 ? 107.716 135.570 127.470 1.00 109.94 ? 251 GLU C OE1 1 
ATOM   5291 O OE2 . GLU C 1 251 ? 108.040 133.784 126.235 1.00 109.94 ? 251 GLU C OE2 1 
ATOM   5292 N N   . LEU C 1 252 ? 112.320 131.645 127.491 1.00 106.38 ? 252 LEU C N   1 
ATOM   5293 C CA  . LEU C 1 252 ? 112.348 130.360 128.179 1.00 106.38 ? 252 LEU C CA  1 
ATOM   5294 C C   . LEU C 1 252 ? 113.570 130.253 129.082 1.00 106.38 ? 252 LEU C C   1 
ATOM   5295 O O   . LEU C 1 252 ? 113.482 129.756 130.213 1.00 106.38 ? 252 LEU C O   1 
ATOM   5296 C CB  . LEU C 1 252 ? 112.334 129.230 127.157 1.00 106.38 ? 252 LEU C CB  1 
ATOM   5297 C CG  . LEU C 1 252 ? 111.741 127.921 127.642 1.00 106.38 ? 252 LEU C CG  1 
ATOM   5298 C CD1 . LEU C 1 252 ? 110.258 128.115 127.907 1.00 106.38 ? 252 LEU C CD1 1 
ATOM   5299 C CD2 . LEU C 1 252 ? 111.984 126.832 126.615 1.00 106.38 ? 252 LEU C CD2 1 
ATOM   5300 N N   . THR C 1 253 ? 114.728 130.705 128.594 1.00 104.10 ? 253 THR C N   1 
ATOM   5301 C CA  . THR C 1 253 ? 115.896 130.783 129.462 1.00 104.10 ? 253 THR C CA  1 
ATOM   5302 C C   . THR C 1 253 ? 115.641 131.659 130.668 1.00 104.10 ? 253 THR C C   1 
ATOM   5303 O O   . THR C 1 253 ? 116.052 131.299 131.772 1.00 104.10 ? 253 THR C O   1 
ATOM   5304 C CB  . THR C 1 253 ? 117.110 131.357 128.734 1.00 104.10 ? 253 THR C CB  1 
ATOM   5305 O OG1 . THR C 1 253 ? 116.980 132.782 128.663 1.00 104.10 ? 253 THR C OG1 1 
ATOM   5306 C CG2 . THR C 1 253 ? 117.216 130.809 127.338 1.00 104.10 ? 253 THR C CG2 1 
ATOM   5307 N N   . PHE C 1 254 ? 114.993 132.803 130.472 1.00 96.15  ? 254 PHE C N   1 
ATOM   5308 C CA  . PHE C 1 254 ? 114.682 133.672 131.599 1.00 96.15  ? 254 PHE C CA  1 
ATOM   5309 C C   . PHE C 1 254 ? 113.785 132.958 132.599 1.00 96.15  ? 254 PHE C C   1 
ATOM   5310 O O   . PHE C 1 254 ? 113.964 133.083 133.817 1.00 96.15  ? 254 PHE C O   1 
ATOM   5311 C CB  . PHE C 1 254 ? 114.018 134.952 131.105 1.00 96.15  ? 254 PHE C CB  1 
ATOM   5312 C CG  . PHE C 1 254 ? 113.414 135.773 132.194 1.00 96.15  ? 254 PHE C CG  1 
ATOM   5313 C CD1 . PHE C 1 254 ? 114.195 136.640 132.930 1.00 96.15  ? 254 PHE C CD1 1 
ATOM   5314 C CD2 . PHE C 1 254 ? 112.073 135.669 132.494 1.00 96.15  ? 254 PHE C CD2 1 
ATOM   5315 C CE1 . PHE C 1 254 ? 113.645 137.396 133.936 1.00 96.15  ? 254 PHE C CE1 1 
ATOM   5316 C CE2 . PHE C 1 254 ? 111.524 136.416 133.499 1.00 96.15  ? 254 PHE C CE2 1 
ATOM   5317 C CZ  . PHE C 1 254 ? 112.307 137.282 134.221 1.00 96.15  ? 254 PHE C CZ  1 
ATOM   5318 N N   . HIS C 1 255 ? 112.801 132.212 132.098 1.00 94.78  ? 255 HIS C N   1 
ATOM   5319 C CA  . HIS C 1 255 ? 111.936 131.446 132.985 1.00 94.78  ? 255 HIS C CA  1 
ATOM   5320 C C   . HIS C 1 255 ? 112.712 130.427 133.802 1.00 94.78  ? 255 HIS C C   1 
ATOM   5321 O O   . HIS C 1 255 ? 112.524 130.340 135.019 1.00 94.78  ? 255 HIS C O   1 
ATOM   5322 C CB  . HIS C 1 255 ? 110.855 130.730 132.187 1.00 94.78  ? 255 HIS C CB  1 
ATOM   5323 C CG  . HIS C 1 255 ? 110.041 129.787 133.008 1.00 94.78  ? 255 HIS C CG  1 
ATOM   5324 N ND1 . HIS C 1 255 ? 110.367 128.456 133.145 1.00 94.78  ? 255 HIS C ND1 1 
ATOM   5325 C CD2 . HIS C 1 255 ? 108.926 129.982 133.749 1.00 94.78  ? 255 HIS C CD2 1 
ATOM   5326 C CE1 . HIS C 1 255 ? 109.482 127.869 133.927 1.00 94.78  ? 255 HIS C CE1 1 
ATOM   5327 N NE2 . HIS C 1 255 ? 108.598 128.772 134.308 1.00 94.78  ? 255 HIS C NE2 1 
ATOM   5328 N N   . HIS C 1 256 ? 113.574 129.642 133.162 1.00 92.58  ? 256 HIS C N   1 
ATOM   5329 C CA  . HIS C 1 256 ? 114.359 128.680 133.925 1.00 92.58  ? 256 HIS C CA  1 
ATOM   5330 C C   . HIS C 1 256 ? 115.289 129.360 134.921 1.00 92.58  ? 256 HIS C C   1 
ATOM   5331 O O   . HIS C 1 256 ? 115.435 128.874 136.049 1.00 92.58  ? 256 HIS C O   1 
ATOM   5332 C CB  . HIS C 1 256 ? 115.165 127.772 132.997 1.00 92.58  ? 256 HIS C CB  1 
ATOM   5333 C CG  . HIS C 1 256 ? 114.323 126.881 132.141 1.00 92.58  ? 256 HIS C CG  1 
ATOM   5334 N ND1 . HIS C 1 256 ? 114.131 127.108 130.797 1.00 92.58  ? 256 HIS C ND1 1 
ATOM   5335 C CD2 . HIS C 1 256 ? 113.608 125.774 132.441 1.00 92.58  ? 256 HIS C CD2 1 
ATOM   5336 C CE1 . HIS C 1 256 ? 113.346 126.169 130.302 1.00 92.58  ? 256 HIS C CE1 1 
ATOM   5337 N NE2 . HIS C 1 256 ? 113.014 125.347 131.280 1.00 92.58  ? 256 HIS C NE2 1 
ATOM   5338 N N   . ILE C 1 257 ? 115.904 130.478 134.541 1.00 87.32  ? 257 ILE C N   1 
ATOM   5339 C CA  . ILE C 1 257 ? 116.782 131.183 135.463 1.00 87.32  ? 257 ILE C CA  1 
ATOM   5340 C C   . ILE C 1 257 ? 116.019 131.666 136.687 1.00 87.32  ? 257 ILE C C   1 
ATOM   5341 O O   . ILE C 1 257 ? 116.475 131.480 137.821 1.00 87.32  ? 257 ILE C O   1 
ATOM   5342 C CB  . ILE C 1 257 ? 117.479 132.349 134.746 1.00 87.32  ? 257 ILE C CB  1 
ATOM   5343 C CG1 . ILE C 1 257 ? 118.459 131.820 133.701 1.00 87.32  ? 257 ILE C CG1 1 
ATOM   5344 C CG2 . ILE C 1 257 ? 118.188 133.241 135.741 1.00 87.32  ? 257 ILE C CG2 1 
ATOM   5345 C CD1 . ILE C 1 257 ? 119.494 130.865 134.252 1.00 87.32  ? 257 ILE C CD1 1 
ATOM   5346 N N   . VAL C 1 258 ? 114.849 132.274 136.503 1.00 84.76  ? 258 VAL C N   1 
ATOM   5347 C CA  . VAL C 1 258 ? 114.107 132.747 137.664 1.00 84.76  ? 258 VAL C CA  1 
ATOM   5348 C C   . VAL C 1 258 ? 113.522 131.600 138.480 1.00 84.76  ? 258 VAL C C   1 
ATOM   5349 O O   . VAL C 1 258 ? 113.412 131.721 139.707 1.00 84.76  ? 258 VAL C O   1 
ATOM   5350 C CB  . VAL C 1 258 ? 112.999 133.734 137.269 1.00 84.76  ? 258 VAL C CB  1 
ATOM   5351 C CG1 . VAL C 1 258 ? 111.862 133.026 136.560 1.00 84.76  ? 258 VAL C CG1 1 
ATOM   5352 C CG2 . VAL C 1 258 ? 112.506 134.479 138.496 1.00 84.76  ? 258 VAL C CG2 1 
ATOM   5353 N N   . THR C 1 259 ? 113.159 130.484 137.846 1.00 80.90  ? 259 THR C N   1 
ATOM   5354 C CA  . THR C 1 259 ? 112.712 129.329 138.611 1.00 80.90  ? 259 THR C CA  1 
ATOM   5355 C C   . THR C 1 259 ? 113.819 128.816 139.515 1.00 80.90  ? 259 THR C C   1 
ATOM   5356 O O   . THR C 1 259 ? 113.584 128.519 140.693 1.00 80.90  ? 259 THR C O   1 
ATOM   5357 C CB  . THR C 1 259 ? 112.233 128.225 137.673 1.00 80.90  ? 259 THR C CB  1 
ATOM   5358 O OG1 . THR C 1 259 ? 111.008 128.623 137.052 1.00 80.90  ? 259 THR C OG1 1 
ATOM   5359 C CG2 . THR C 1 259 ? 112.009 126.947 138.435 1.00 80.90  ? 259 THR C CG2 1 
ATOM   5360 N N   . LEU C 1 260 ? 115.039 128.708 138.991 1.00 74.81  ? 260 LEU C N   1 
ATOM   5361 C CA  . LEU C 1 260 ? 116.136 128.297 139.858 1.00 74.81  ? 260 LEU C CA  1 
ATOM   5362 C C   . LEU C 1 260 ? 116.444 129.319 140.934 1.00 74.81  ? 260 LEU C C   1 
ATOM   5363 O O   . LEU C 1 260 ? 116.794 128.928 142.048 1.00 74.81  ? 260 LEU C O   1 
ATOM   5364 C CB  . LEU C 1 260 ? 117.411 128.011 139.073 1.00 74.81  ? 260 LEU C CB  1 
ATOM   5365 C CG  . LEU C 1 260 ? 117.526 126.627 138.450 1.00 74.81  ? 260 LEU C CG  1 
ATOM   5366 C CD1 . LEU C 1 260 ? 117.553 125.599 139.555 1.00 74.81  ? 260 LEU C CD1 1 
ATOM   5367 C CD2 . LEU C 1 260 ? 116.422 126.345 137.486 1.00 74.81  ? 260 LEU C CD2 1 
ATOM   5368 N N   . LEU C 1 261 ? 116.340 130.609 140.636 1.00 73.60  ? 261 LEU C N   1 
ATOM   5369 C CA  . LEU C 1 261 ? 116.561 131.578 141.699 1.00 73.60  ? 261 LEU C CA  1 
ATOM   5370 C C   . LEU C 1 261 ? 115.534 131.416 142.808 1.00 73.60  ? 261 LEU C C   1 
ATOM   5371 O O   . LEU C 1 261 ? 115.894 131.423 143.987 1.00 73.60  ? 261 LEU C O   1 
ATOM   5372 C CB  . LEU C 1 261 ? 116.536 132.997 141.146 1.00 73.60  ? 261 LEU C CB  1 
ATOM   5373 C CG  . LEU C 1 261 ? 117.721 133.359 140.258 1.00 73.60  ? 261 LEU C CG  1 
ATOM   5374 C CD1 . LEU C 1 261 ? 117.629 134.803 139.843 1.00 73.60  ? 261 LEU C CD1 1 
ATOM   5375 C CD2 . LEU C 1 261 ? 119.021 133.089 140.971 1.00 73.60  ? 261 LEU C CD2 1 
ATOM   5376 N N   . LEU C 1 262 ? 114.262 131.229 142.457 1.00 72.63  ? 262 LEU C N   1 
ATOM   5377 C CA  . LEU C 1 262 ? 113.261 130.936 143.477 1.00 72.63  ? 262 LEU C CA  1 
ATOM   5378 C C   . LEU C 1 262 ? 113.646 129.717 144.295 1.00 72.63  ? 262 LEU C C   1 
ATOM   5379 O O   . LEU C 1 262 ? 113.723 129.790 145.526 1.00 72.63  ? 262 LEU C O   1 
ATOM   5380 C CB  . LEU C 1 262 ? 111.897 130.697 142.841 1.00 72.63  ? 262 LEU C CB  1 
ATOM   5381 C CG  . LEU C 1 262 ? 111.134 131.780 142.096 1.00 72.63  ? 262 LEU C CG  1 
ATOM   5382 C CD1 . LEU C 1 262 ? 109.667 131.414 142.072 1.00 72.63  ? 262 LEU C CD1 1 
ATOM   5383 C CD2 . LEU C 1 262 ? 111.313 133.086 142.780 1.00 72.63  ? 262 LEU C CD2 1 
ATOM   5384 N N   . ILE C 1 263 ? 113.919 128.595 143.627 1.00 65.77  ? 263 ILE C N   1 
ATOM   5385 C CA  . ILE C 1 263 ? 114.138 127.348 144.350 1.00 65.77  ? 263 ILE C CA  1 
ATOM   5386 C C   . ILE C 1 263 ? 115.327 127.480 145.285 1.00 65.77  ? 263 ILE C C   1 
ATOM   5387 O O   . ILE C 1 263 ? 115.235 127.197 146.484 1.00 65.77  ? 263 ILE C O   1 
ATOM   5388 C CB  . ILE C 1 263 ? 114.348 126.181 143.373 1.00 65.77  ? 263 ILE C CB  1 
ATOM   5389 C CG1 . ILE C 1 263 ? 113.085 125.882 142.585 1.00 65.77  ? 263 ILE C CG1 1 
ATOM   5390 C CG2 . ILE C 1 263 ? 114.748 124.962 144.130 1.00 65.77  ? 263 ILE C CG2 1 
ATOM   5391 C CD1 . ILE C 1 263 ? 113.206 124.669 141.730 1.00 65.77  ? 263 ILE C CD1 1 
ATOM   5392 N N   . TRP C 1 264 ? 116.451 127.947 144.756 1.00 66.55  ? 264 TRP C N   1 
ATOM   5393 C CA  . TRP C 1 264 ? 117.673 127.990 145.538 1.00 66.55  ? 264 TRP C CA  1 
ATOM   5394 C C   . TRP C 1 264 ? 117.588 129.018 146.654 1.00 66.55  ? 264 TRP C C   1 
ATOM   5395 O O   . TRP C 1 264 ? 117.915 128.718 147.805 1.00 66.55  ? 264 TRP C O   1 
ATOM   5396 C CB  . TRP C 1 264 ? 118.849 128.285 144.619 1.00 66.55  ? 264 TRP C CB  1 
ATOM   5397 C CG  . TRP C 1 264 ? 120.026 128.798 145.322 1.00 66.55  ? 264 TRP C CG  1 
ATOM   5398 C CD1 . TRP C 1 264 ? 120.846 128.104 146.145 1.00 66.55  ? 264 TRP C CD1 1 
ATOM   5399 C CD2 . TRP C 1 264 ? 120.537 130.126 145.271 1.00 66.55  ? 264 TRP C CD2 1 
ATOM   5400 N NE1 . TRP C 1 264 ? 121.840 128.914 146.614 1.00 66.55  ? 264 TRP C NE1 1 
ATOM   5401 C CE2 . TRP C 1 264 ? 121.669 130.166 146.090 1.00 66.55  ? 264 TRP C CE2 1 
ATOM   5402 C CE3 . TRP C 1 264 ? 120.142 131.286 144.612 1.00 66.55  ? 264 TRP C CE3 1 
ATOM   5403 C CZ2 . TRP C 1 264 ? 122.410 131.315 146.270 1.00 66.55  ? 264 TRP C CZ2 1 
ATOM   5404 C CZ3 . TRP C 1 264 ? 120.877 132.422 144.792 1.00 66.55  ? 264 TRP C CZ3 1 
ATOM   5405 C CH2 . TRP C 1 264 ? 121.998 132.433 145.612 1.00 66.55  ? 264 TRP C CH2 1 
ATOM   5406 N N   . SER C 1 265 ? 117.154 130.237 146.345 1.00 64.63  ? 265 SER C N   1 
ATOM   5407 C CA  . SER C 1 265 ? 117.138 131.271 147.359 1.00 64.63  ? 265 SER C CA  1 
ATOM   5408 C C   . SER C 1 265 ? 116.044 131.066 148.385 1.00 64.63  ? 265 SER C C   1 
ATOM   5409 O O   . SER C 1 265 ? 116.070 131.724 149.425 1.00 64.63  ? 265 SER C O   1 
ATOM   5410 C CB  . SER C 1 265 ? 116.973 132.638 146.708 1.00 64.63  ? 265 SER C CB  1 
ATOM   5411 O OG  . SER C 1 265 ? 115.970 132.602 145.714 1.00 64.63  ? 265 SER C OG  1 
ATOM   5412 N N   . SER C 1 266 ? 115.081 130.185 148.130 1.00 63.06  ? 266 SER C N   1 
ATOM   5413 C CA  . SER C 1 266 ? 114.115 129.901 149.177 1.00 63.06  ? 266 SER C CA  1 
ATOM   5414 C C   . SER C 1 266 ? 114.499 128.681 149.994 1.00 63.06  ? 266 SER C C   1 
ATOM   5415 O O   . SER C 1 266 ? 114.126 128.592 151.165 1.00 63.06  ? 266 SER C O   1 
ATOM   5416 C CB  . SER C 1 266 ? 112.731 129.721 148.577 1.00 63.06  ? 266 SER C CB  1 
ATOM   5417 O OG  . SER C 1 266 ? 112.688 128.583 147.755 1.00 63.06  ? 266 SER C OG  1 
ATOM   5418 N N   . TYR C 1 267 ? 115.230 127.732 149.417 1.00 58.93  ? 267 TYR C N   1 
ATOM   5419 C CA  . TYR C 1 267 ? 115.734 126.630 150.223 1.00 58.93  ? 267 TYR C CA  1 
ATOM   5420 C C   . TYR C 1 267 ? 116.889 127.046 151.113 1.00 58.93  ? 267 TYR C C   1 
ATOM   5421 O O   . TYR C 1 267 ? 116.935 126.642 152.276 1.00 58.93  ? 267 TYR C O   1 
ATOM   5422 C CB  . TYR C 1 267 ? 116.178 125.490 149.326 1.00 58.93  ? 267 TYR C CB  1 
ATOM   5423 C CG  . TYR C 1 267 ? 116.548 124.235 150.057 1.00 58.93  ? 267 TYR C CG  1 
ATOM   5424 C CD1 . TYR C 1 267 ? 117.866 123.873 150.217 1.00 58.93  ? 267 TYR C CD1 1 
ATOM   5425 C CD2 . TYR C 1 267 ? 115.579 123.412 150.581 1.00 58.93  ? 267 TYR C CD2 1 
ATOM   5426 C CE1 . TYR C 1 267 ? 118.205 122.726 150.872 1.00 58.93  ? 267 TYR C CE1 1 
ATOM   5427 C CE2 . TYR C 1 267 ? 115.907 122.269 151.238 1.00 58.93  ? 267 TYR C CE2 1 
ATOM   5428 C CZ  . TYR C 1 267 ? 117.221 121.929 151.382 1.00 58.93  ? 267 TYR C CZ  1 
ATOM   5429 O OH  . TYR C 1 267 ? 117.552 120.778 152.046 1.00 58.93  ? 267 TYR C OH  1 
ATOM   5430 N N   . VAL C 1 268 ? 117.816 127.851 150.592 1.00 59.13  ? 268 VAL C N   1 
ATOM   5431 C CA  . VAL C 1 268 ? 118.962 128.311 151.361 1.00 59.13  ? 268 VAL C CA  1 
ATOM   5432 C C   . VAL C 1 268 ? 118.574 129.231 152.504 1.00 59.13  ? 268 VAL C C   1 
ATOM   5433 O O   . VAL C 1 268 ? 119.134 129.108 153.599 1.00 59.13  ? 268 VAL C O   1 
ATOM   5434 C CB  . VAL C 1 268 ? 119.953 129.002 150.407 1.00 59.13  ? 268 VAL C CB  1 
ATOM   5435 C CG1 . VAL C 1 268 ? 120.898 129.878 151.159 1.00 59.13  ? 268 VAL C CG1 1 
ATOM   5436 C CG2 . VAL C 1 268 ? 120.716 127.966 149.637 1.00 59.13  ? 268 VAL C CG2 1 
ATOM   5437 N N   . PHE C 1 269 ? 117.629 130.141 152.293 1.00 62.07  ? 269 PHE C N   1 
ATOM   5438 C CA  . PHE C 1 269 ? 117.263 131.114 153.309 1.00 62.07  ? 269 PHE C CA  1 
ATOM   5439 C C   . PHE C 1 269 ? 116.032 130.701 154.098 1.00 62.07  ? 269 PHE C C   1 
ATOM   5440 O O   . PHE C 1 269 ? 115.407 131.556 154.730 1.00 62.07  ? 269 PHE C O   1 
ATOM   5441 C CB  . PHE C 1 269 ? 117.039 132.485 152.679 1.00 62.07  ? 269 PHE C CB  1 
ATOM   5442 C CG  . PHE C 1 269 ? 118.304 133.194 152.332 1.00 62.07  ? 269 PHE C CG  1 
ATOM   5443 C CD1 . PHE C 1 269 ? 119.135 133.668 153.317 1.00 62.07  ? 269 PHE C CD1 1 
ATOM   5444 C CD2 . PHE C 1 269 ? 118.663 133.382 151.020 1.00 62.07  ? 269 PHE C CD2 1 
ATOM   5445 C CE1 . PHE C 1 269 ? 120.298 134.314 152.999 1.00 62.07  ? 269 PHE C CE1 1 
ATOM   5446 C CE2 . PHE C 1 269 ? 119.825 134.028 150.703 1.00 62.07  ? 269 PHE C CE2 1 
ATOM   5447 C CZ  . PHE C 1 269 ? 120.643 134.493 151.694 1.00 62.07  ? 269 PHE C CZ  1 
ATOM   5448 N N   . HIS C 1 270 ? 115.660 129.427 154.060 1.00 64.28  ? 270 HIS C N   1 
ATOM   5449 C CA  . HIS C 1 270 ? 114.653 128.821 154.921 1.00 64.28  ? 270 HIS C CA  1 
ATOM   5450 C C   . HIS C 1 270 ? 113.231 129.273 154.627 1.00 64.28  ? 270 HIS C C   1 
ATOM   5451 O O   . HIS C 1 270 ? 112.335 129.003 155.423 1.00 64.28  ? 270 HIS C O   1 
ATOM   5452 C CB  . HIS C 1 270 ? 114.960 129.078 156.392 1.00 64.28  ? 270 HIS C CB  1 
ATOM   5453 C CG  . HIS C 1 270 ? 116.403 128.926 156.746 1.00 64.28  ? 270 HIS C CG  1 
ATOM   5454 N ND1 . HIS C 1 270 ? 117.040 127.706 156.762 1.00 64.28  ? 270 HIS C ND1 1 
ATOM   5455 C CD2 . HIS C 1 270 ? 117.335 129.839 157.097 1.00 64.28  ? 270 HIS C CD2 1 
ATOM   5456 C CE1 . HIS C 1 270 ? 118.302 127.874 157.103 1.00 64.28  ? 270 HIS C CE1 1 
ATOM   5457 N NE2 . HIS C 1 270 ? 118.508 129.160 157.313 1.00 64.28  ? 270 HIS C NE2 1 
ATOM   5458 N N   . PHE C 1 271 ? 112.985 129.942 153.505 1.00 66.89  ? 271 PHE C N   1 
ATOM   5459 C CA  . PHE C 1 271 ? 111.640 130.380 153.145 1.00 66.89  ? 271 PHE C CA  1 
ATOM   5460 C C   . PHE C 1 271 ? 110.951 129.305 152.315 1.00 66.89  ? 271 PHE C C   1 
ATOM   5461 O O   . PHE C 1 271 ? 110.398 129.563 151.254 1.00 66.89  ? 271 PHE C O   1 
ATOM   5462 C CB  . PHE C 1 271 ? 111.696 131.678 152.358 1.00 66.89  ? 271 PHE C CB  1 
ATOM   5463 C CG  . PHE C 1 271 ? 111.900 132.891 153.184 1.00 66.89  ? 271 PHE C CG  1 
ATOM   5464 C CD1 . PHE C 1 271 ? 110.834 133.502 153.804 1.00 66.89  ? 271 PHE C CD1 1 
ATOM   5465 C CD2 . PHE C 1 271 ? 113.147 133.457 153.299 1.00 66.89  ? 271 PHE C CD2 1 
ATOM   5466 C CE1 . PHE C 1 271 ? 111.015 134.640 154.545 1.00 66.89  ? 271 PHE C CE1 1 
ATOM   5467 C CE2 . PHE C 1 271 ? 113.333 134.591 154.039 1.00 66.89  ? 271 PHE C CE2 1 
ATOM   5468 C CZ  . PHE C 1 271 ? 112.268 135.185 154.664 1.00 66.89  ? 271 PHE C CZ  1 
ATOM   5469 N N   . THR C 1 272 ? 110.975 128.082 152.819 1.00 66.41  ? 272 THR C N   1 
ATOM   5470 C CA  . THR C 1 272 ? 110.551 126.966 151.990 1.00 66.41  ? 272 THR C CA  1 
ATOM   5471 C C   . THR C 1 272 ? 109.053 126.693 152.059 1.00 66.41  ? 272 THR C C   1 
ATOM   5472 O O   . THR C 1 272 ? 108.448 126.356 151.031 1.00 66.41  ? 272 THR C O   1 
ATOM   5473 C CB  . THR C 1 272 ? 111.356 125.715 152.355 1.00 66.41  ? 272 THR C CB  1 
ATOM   5474 O OG1 . THR C 1 272 ? 111.062 124.673 151.428 1.00 66.41  ? 272 THR C OG1 1 
ATOM   5475 C CG2 . THR C 1 272 ? 111.065 125.257 153.760 1.00 66.41  ? 272 THR C CG2 1 
ATOM   5476 N N   . LYS C 1 273 ? 108.422 126.880 153.220 1.00 73.50  ? 273 LYS C N   1 
ATOM   5477 C CA  . LYS C 1 273 ? 106.969 126.795 153.266 1.00 73.50  ? 273 LYS C CA  1 
ATOM   5478 C C   . LYS C 1 273 ? 106.336 127.830 152.357 1.00 73.50  ? 273 LYS C C   1 
ATOM   5479 O O   . LYS C 1 273 ? 105.369 127.536 151.653 1.00 73.50  ? 273 LYS C O   1 
ATOM   5480 C CB  . LYS C 1 273 ? 106.446 126.972 154.688 1.00 73.50  ? 273 LYS C CB  1 
ATOM   5481 C CG  . LYS C 1 273 ? 106.791 125.867 155.647 1.00 73.50  ? 273 LYS C CG  1 
ATOM   5482 C CD  . LYS C 1 273 ? 106.158 126.145 156.996 1.00 73.50  ? 273 LYS C CD  1 
ATOM   5483 C CE  . LYS C 1 273 ? 106.537 125.099 158.023 1.00 73.50  ? 273 LYS C CE  1 
ATOM   5484 N NZ  . LYS C 1 273 ? 105.949 123.780 157.694 1.00 73.50  ? 273 LYS C NZ  1 
ATOM   5485 N N   . MET C 1 274 ? 106.868 129.048 152.347 1.00 77.55  ? 274 MET C N   1 
ATOM   5486 C CA  . MET C 1 274 ? 106.286 130.084 151.508 1.00 77.55  ? 274 MET C CA  1 
ATOM   5487 C C   . MET C 1 274 ? 106.631 129.849 150.044 1.00 77.55  ? 274 MET C C   1 
ATOM   5488 O O   . MET C 1 274 ? 106.034 130.451 149.147 1.00 77.55  ? 274 MET C O   1 
ATOM   5489 C CB  . MET C 1 274 ? 106.744 131.457 152.002 1.00 77.55  ? 274 MET C CB  1 
ATOM   5490 C CG  . MET C 1 274 ? 106.385 132.640 151.138 1.00 77.55  ? 274 MET C CG  1 
ATOM   5491 S SD  . MET C 1 274 ? 107.622 133.933 151.187 1.00 77.55  ? 274 MET C SD  1 
ATOM   5492 C CE  . MET C 1 274 ? 108.799 133.271 150.040 1.00 77.55  ? 274 MET C CE  1 
ATOM   5493 N N   . GLY C 1 275 ? 107.571 128.944 149.780 1.00 73.42  ? 275 GLY C N   1 
ATOM   5494 C CA  . GLY C 1 275 ? 107.890 128.605 148.407 1.00 73.42  ? 275 GLY C CA  1 
ATOM   5495 C C   . GLY C 1 275 ? 107.076 127.454 147.854 1.00 73.42  ? 275 GLY C C   1 
ATOM   5496 O O   . GLY C 1 275 ? 106.994 127.287 146.637 1.00 73.42  ? 275 GLY C O   1 
ATOM   5497 N N   . LEU C 1 276 ? 106.489 126.635 148.721 1.00 74.84  ? 276 LEU C N   1 
ATOM   5498 C CA  . LEU C 1 276 ? 105.659 125.530 148.233 1.00 74.84  ? 276 LEU C CA  1 
ATOM   5499 C C   . LEU C 1 276 ? 104.438 125.962 147.420 1.00 74.84  ? 276 LEU C C   1 
ATOM   5500 O O   . LEU C 1 276 ? 104.244 125.432 146.311 1.00 74.84  ? 276 LEU C O   1 
ATOM   5501 C CB  . LEU C 1 276 ? 105.227 124.658 149.415 1.00 74.84  ? 276 LEU C CB  1 
ATOM   5502 C CG  . LEU C 1 276 ? 104.503 123.378 149.026 1.00 74.84  ? 276 LEU C CG  1 
ATOM   5503 C CD1 . LEU C 1 276 ? 105.470 122.413 148.405 1.00 74.84  ? 276 LEU C CD1 1 
ATOM   5504 C CD2 . LEU C 1 276 ? 103.842 122.760 150.233 1.00 74.84  ? 276 LEU C CD2 1 
ATOM   5505 N N   . PRO C 1 277 ? 103.580 126.876 147.890 1.00 77.16  ? 277 PRO C N   1 
ATOM   5506 C CA  . PRO C 1 277 ? 102.393 127.222 147.097 1.00 77.16  ? 277 PRO C CA  1 
ATOM   5507 C C   . PRO C 1 277 ? 102.715 127.762 145.723 1.00 77.16  ? 277 PRO C C   1 
ATOM   5508 O O   . PRO C 1 277 ? 101.963 127.524 144.773 1.00 77.16  ? 277 PRO C O   1 
ATOM   5509 C CB  . PRO C 1 277 ? 101.704 128.277 147.963 1.00 77.16  ? 277 PRO C CB  1 
ATOM   5510 C CG  . PRO C 1 277 ? 102.126 127.959 149.314 1.00 77.16  ? 277 PRO C CG  1 
ATOM   5511 C CD  . PRO C 1 277 ? 103.555 127.573 149.181 1.00 77.16  ? 277 PRO C CD  1 
ATOM   5512 N N   . ILE C 1 278 ? 103.809 128.503 145.592 1.00 73.88  ? 278 ILE C N   1 
ATOM   5513 C CA  . ILE C 1 278 ? 104.166 129.035 144.287 1.00 73.88  ? 278 ILE C CA  1 
ATOM   5514 C C   . ILE C 1 278 ? 104.469 127.901 143.319 1.00 73.88  ? 278 ILE C C   1 
ATOM   5515 O O   . ILE C 1 278 ? 104.048 127.933 142.157 1.00 73.88  ? 278 ILE C O   1 
ATOM   5516 C CB  . ILE C 1 278 ? 105.330 130.025 144.427 1.00 73.88  ? 278 ILE C CB  1 
ATOM   5517 C CG1 . ILE C 1 278 ? 104.872 131.200 145.281 1.00 73.88  ? 278 ILE C CG1 1 
ATOM   5518 C CG2 . ILE C 1 278 ? 105.772 130.511 143.080 1.00 73.88  ? 278 ILE C CG2 1 
ATOM   5519 C CD1 . ILE C 1 278 ? 105.977 132.075 145.755 1.00 73.88  ? 278 ILE C CD1 1 
ATOM   5520 N N   . TYR C 1 279 ? 105.166 126.863 143.787 1.00 76.34  ? 279 TYR C N   1 
ATOM   5521 C CA  . TYR C 1 279 ? 105.377 125.692 142.942 1.00 76.34  ? 279 TYR C CA  1 
ATOM   5522 C C   . TYR C 1 279 ? 104.052 125.085 142.542 1.00 76.34  ? 279 TYR C C   1 
ATOM   5523 O O   . TYR C 1 279 ? 103.870 124.666 141.395 1.00 76.34  ? 279 TYR C O   1 
ATOM   5524 C CB  . TYR C 1 279 ? 106.164 124.617 143.669 1.00 76.34  ? 279 TYR C CB  1 
ATOM   5525 C CG  . TYR C 1 279 ? 107.581 124.934 143.986 1.00 76.34  ? 279 TYR C CG  1 
ATOM   5526 C CD1 . TYR C 1 279 ? 108.238 125.995 143.396 1.00 76.34  ? 279 TYR C CD1 1 
ATOM   5527 C CD2 . TYR C 1 279 ? 108.263 124.162 144.903 1.00 76.34  ? 279 TYR C CD2 1 
ATOM   5528 C CE1 . TYR C 1 279 ? 109.545 126.274 143.724 1.00 76.34  ? 279 TYR C CE1 1 
ATOM   5529 C CE2 . TYR C 1 279 ? 109.546 124.421 145.226 1.00 76.34  ? 279 TYR C CE2 1 
ATOM   5530 C CZ  . TYR C 1 279 ? 110.189 125.471 144.645 1.00 76.34  ? 279 TYR C CZ  1 
ATOM   5531 O OH  . TYR C 1 279 ? 111.487 125.698 145.012 1.00 76.34  ? 279 TYR C OH  1 
ATOM   5532 N N   . ILE C 1 280 ? 103.128 124.985 143.495 1.00 79.55  ? 280 ILE C N   1 
ATOM   5533 C CA  . ILE C 1 280 ? 101.850 124.344 143.205 1.00 79.55  ? 280 ILE C CA  1 
ATOM   5534 C C   . ILE C 1 280 ? 101.113 125.098 142.109 1.00 79.55  ? 280 ILE C C   1 
ATOM   5535 O O   . ILE C 1 280 ? 100.604 124.502 141.149 1.00 79.55  ? 280 ILE C O   1 
ATOM   5536 C CB  . ILE C 1 280 ? 101.010 124.240 144.485 1.00 79.55  ? 280 ILE C CB  1 
ATOM   5537 C CG1 . ILE C 1 280 ? 101.568 123.133 145.369 1.00 79.55  ? 280 ILE C CG1 1 
ATOM   5538 C CG2 . ILE C 1 280 ? 99.557  124.004 144.151 1.00 79.55  ? 280 ILE C CG2 1 
ATOM   5539 C CD1 . ILE C 1 280 ? 100.944 123.083 146.712 1.00 79.55  ? 280 ILE C CD1 1 
ATOM   5540 N N   . THR C 1 281 ? 101.047 126.421 142.233 1.00 81.57  ? 281 THR C N   1 
ATOM   5541 C CA  . THR C 1 281 ? 100.349 127.217 141.231 1.00 81.57  ? 281 THR C CA  1 
ATOM   5542 C C   . THR C 1 281 ? 101.013 127.076 139.871 1.00 81.57  ? 281 THR C C   1 
ATOM   5543 O O   . THR C 1 281 ? 100.341 126.843 138.855 1.00 81.57  ? 281 THR C O   1 
ATOM   5544 C CB  . THR C 1 281 ? 100.303 128.682 141.649 1.00 81.57  ? 281 THR C CB  1 
ATOM   5545 O OG1 . THR C 1 281 ? 101.625 129.225 141.632 1.00 81.57  ? 281 THR C OG1 1 
ATOM   5546 C CG2 . THR C 1 281 ? 99.718  128.823 143.036 1.00 81.57  ? 281 THR C CG2 1 
ATOM   5547 N N   . MET C 1 282 ? 102.343 127.188 139.835 1.00 86.06  ? 282 MET C N   1 
ATOM   5548 C CA  . MET C 1 282 ? 103.041 127.105 138.561 1.00 86.06  ? 282 MET C CA  1 
ATOM   5549 C C   . MET C 1 282 ? 102.798 125.758 137.897 1.00 86.06  ? 282 MET C C   1 
ATOM   5550 O O   . MET C 1 282 ? 102.499 125.694 136.700 1.00 86.06  ? 282 MET C O   1 
ATOM   5551 C CB  . MET C 1 282 ? 104.533 127.337 138.767 1.00 86.06  ? 282 MET C CB  1 
ATOM   5552 C CG  . MET C 1 282 ? 104.863 128.726 139.261 1.00 86.06  ? 282 MET C CG  1 
ATOM   5553 S SD  . MET C 1 282 ? 104.428 130.016 138.104 1.00 86.06  ? 282 MET C SD  1 
ATOM   5554 C CE  . MET C 1 282 ? 104.728 131.461 139.106 1.00 86.06  ? 282 MET C CE  1 
ATOM   5555 N N   . ASP C 1 283 ? 102.884 124.671 138.666 1.00 87.41  ? 283 ASP C N   1 
ATOM   5556 C CA  . ASP C 1 283 ? 102.664 123.352 138.091 1.00 87.41  ? 283 ASP C CA  1 
ATOM   5557 C C   . ASP C 1 283 ? 101.248 123.185 137.565 1.00 87.41  ? 283 ASP C C   1 
ATOM   5558 O O   . ASP C 1 283 ? 101.072 122.814 136.403 1.00 87.41  ? 283 ASP C O   1 
ATOM   5559 C CB  . ASP C 1 283 ? 102.965 122.259 139.110 1.00 87.41  ? 283 ASP C CB  1 
ATOM   5560 C CG  . ASP C 1 283 ? 104.449 122.044 139.313 1.00 87.41  ? 283 ASP C CG  1 
ATOM   5561 O OD1 . ASP C 1 283 ? 105.237 122.507 138.467 1.00 87.41  ? 283 ASP C OD1 1 
ATOM   5562 O OD2 . ASP C 1 283 ? 104.825 121.386 140.305 1.00 87.41  ? 283 ASP C OD2 1 
ATOM   5563 N N   . VAL C 1 284 ? 100.228 123.464 138.374 1.00 86.29  ? 284 VAL C N   1 
ATOM   5564 C CA  . VAL C 1 284 ? 98.872  123.204 137.894 1.00 86.29  ? 284 VAL C CA  1 
ATOM   5565 C C   . VAL C 1 284 ? 98.563  124.044 136.657 1.00 86.29  ? 284 VAL C C   1 
ATOM   5566 O O   . VAL C 1 284 ? 97.957  123.552 135.689 1.00 86.29  ? 284 VAL C O   1 
ATOM   5567 C CB  . VAL C 1 284 ? 97.849  123.442 139.015 1.00 86.29  ? 284 VAL C CB  1 
ATOM   5568 C CG1 . VAL C 1 284 ? 96.469  123.055 138.539 1.00 86.29  ? 284 VAL C CG1 1 
ATOM   5569 C CG2 . VAL C 1 284 ? 98.217  122.641 140.232 1.00 86.29  ? 284 VAL C CG2 1 
ATOM   5570 N N   . SER C 1 285 ? 98.994  125.308 136.654 1.00 91.23  ? 285 SER C N   1 
ATOM   5571 C CA  . SER C 1 285 ? 98.801  126.128 135.468 1.00 91.23  ? 285 SER C CA  1 
ATOM   5572 C C   . SER C 1 285 ? 99.506  125.522 134.263 1.00 91.23  ? 285 SER C C   1 
ATOM   5573 O O   . SER C 1 285 ? 98.944  125.480 133.162 1.00 91.23  ? 285 SER C O   1 
ATOM   5574 C CB  . SER C 1 285 ? 99.307  127.543 135.718 1.00 91.23  ? 285 SER C CB  1 
ATOM   5575 O OG  . SER C 1 285 ? 100.707 127.540 135.908 1.00 91.23  ? 285 SER C OG  1 
ATOM   5576 N N   . ASP C 1 286 ? 100.732 125.032 134.450 1.00 93.68  ? 286 ASP C N   1 
ATOM   5577 C CA  . ASP C 1 286 ? 101.448 124.444 133.327 1.00 93.68  ? 286 ASP C CA  1 
ATOM   5578 C C   . ASP C 1 286 ? 100.826 123.133 132.876 1.00 93.68  ? 286 ASP C C   1 
ATOM   5579 O O   . ASP C 1 286 ? 100.857 122.822 131.685 1.00 93.68  ? 286 ASP C O   1 
ATOM   5580 C CB  . ASP C 1 286 ? 102.915 124.249 133.684 1.00 93.68  ? 286 ASP C CB  1 
ATOM   5581 C CG  . ASP C 1 286 ? 103.654 125.557 133.788 1.00 93.68  ? 286 ASP C CG  1 
ATOM   5582 O OD1 . ASP C 1 286 ? 102.980 126.605 133.850 1.00 93.68  ? 286 ASP C OD1 1 
ATOM   5583 O OD2 . ASP C 1 286 ? 104.902 125.545 133.801 1.00 93.68  ? 286 ASP C OD2 1 
ATOM   5584 N N   . PHE C 1 287 ? 100.263 122.351 133.794 1.00 90.12  ? 287 PHE C N   1 
ATOM   5585 C CA  . PHE C 1 287 ? 99.571  121.137 133.373 1.00 90.12  ? 287 PHE C CA  1 
ATOM   5586 C C   . PHE C 1 287 ? 98.396  121.448 132.467 1.00 90.12  ? 287 PHE C C   1 
ATOM   5587 O O   . PHE C 1 287 ? 98.234  120.816 131.416 1.00 90.12  ? 287 PHE C O   1 
ATOM   5588 C CB  . PHE C 1 287 ? 99.088  120.358 134.587 1.00 90.12  ? 287 PHE C CB  1 
ATOM   5589 C CG  . PHE C 1 287 ? 98.178  119.224 134.254 1.00 90.12  ? 287 PHE C CG  1 
ATOM   5590 C CD1 . PHE C 1 287 ? 98.683  118.034 133.788 1.00 90.12  ? 287 PHE C CD1 1 
ATOM   5591 C CD2 . PHE C 1 287 ? 96.816  119.345 134.424 1.00 90.12  ? 287 PHE C CD2 1 
ATOM   5592 C CE1 . PHE C 1 287 ? 97.846  116.988 133.490 1.00 90.12  ? 287 PHE C CE1 1 
ATOM   5593 C CE2 . PHE C 1 287 ? 95.975  118.305 134.128 1.00 90.12  ? 287 PHE C CE2 1 
ATOM   5594 C CZ  . PHE C 1 287 ? 96.490  117.124 133.658 1.00 90.12  ? 287 PHE C CZ  1 
ATOM   5595 N N   . LEU C 1 288 ? 97.570  122.421 132.849 1.00 94.81  ? 288 LEU C N   1 
ATOM   5596 C CA  . LEU C 1 288 ? 96.434  122.764 131.998 1.00 94.81  ? 288 LEU C CA  1 
ATOM   5597 C C   . LEU C 1 288 ? 96.890  123.389 130.684 1.00 94.81  ? 288 LEU C C   1 
ATOM   5598 O O   . LEU C 1 288 ? 96.317  123.110 129.621 1.00 94.81  ? 288 LEU C O   1 
ATOM   5599 C CB  . LEU C 1 288 ? 95.482  123.680 132.753 1.00 94.81  ? 288 LEU C CB  1 
ATOM   5600 C CG  . LEU C 1 288 ? 94.846  122.902 133.899 1.00 94.81  ? 288 LEU C CG  1 
ATOM   5601 C CD1 . LEU C 1 288 ? 94.392  123.821 135.007 1.00 94.81  ? 288 LEU C CD1 1 
ATOM   5602 C CD2 . LEU C 1 288 ? 93.699  122.061 133.375 1.00 94.81  ? 288 LEU C CD2 1 
ATOM   5603 N N   . LEU C 1 289 ? 97.934  124.216 130.732 1.00 99.23  ? 289 LEU C N   1 
ATOM   5604 C CA  . LEU C 1 289 ? 98.476  124.795 129.509 1.00 99.23  ? 289 LEU C CA  1 
ATOM   5605 C C   . LEU C 1 289 ? 98.982  123.721 128.557 1.00 99.23  ? 289 LEU C C   1 
ATOM   5606 O O   . LEU C 1 289 ? 98.751  123.799 127.348 1.00 99.23  ? 289 LEU C O   1 
ATOM   5607 C CB  . LEU C 1 289 ? 99.602  125.766 129.844 1.00 99.23  ? 289 LEU C CB  1 
ATOM   5608 C CG  . LEU C 1 289 ? 100.349 126.298 128.627 1.00 99.23  ? 289 LEU C CG  1 
ATOM   5609 C CD1 . LEU C 1 289 ? 99.418  127.118 127.759 1.00 99.23  ? 289 LEU C CD1 1 
ATOM   5610 C CD2 . LEU C 1 289 ? 101.557 127.110 129.049 1.00 99.23  ? 289 LEU C CD2 1 
ATOM   5611 N N   . SER C 1 290 ? 99.688  122.719 129.081 1.00 101.61 ? 290 SER C N   1 
ATOM   5612 C CA  . SER C 1 290 ? 100.210 121.653 128.240 1.00 101.61 ? 290 SER C CA  1 
ATOM   5613 C C   . SER C 1 290 ? 99.104  120.792 127.663 1.00 101.61 ? 290 SER C C   1 
ATOM   5614 O O   . SER C 1 290 ? 99.166  120.414 126.488 1.00 101.61 ? 290 SER C O   1 
ATOM   5615 C CB  . SER C 1 290 ? 101.183 120.791 129.035 1.00 101.61 ? 290 SER C CB  1 
ATOM   5616 O OG  . SER C 1 290 ? 102.179 121.595 129.637 1.00 101.61 ? 290 SER C OG  1 
ATOM   5617 N N   . PHE C 1 291 ? 98.083  120.481 128.458 1.00 105.98 ? 291 PHE C N   1 
ATOM   5618 C CA  . PHE C 1 291 ? 96.935  119.762 127.921 1.00 105.98 ? 291 PHE C CA  1 
ATOM   5619 C C   . PHE C 1 291 ? 96.314  120.516 126.753 1.00 105.98 ? 291 PHE C C   1 
ATOM   5620 O O   . PHE C 1 291 ? 96.092  119.946 125.675 1.00 105.98 ? 291 PHE C O   1 
ATOM   5621 C CB  . PHE C 1 291 ? 95.908  119.543 129.026 1.00 105.98 ? 291 PHE C CB  1 
ATOM   5622 C CG  . PHE C 1 291 ? 95.054  118.344 128.823 1.00 105.98 ? 291 PHE C CG  1 
ATOM   5623 C CD1 . PHE C 1 291 ? 95.619  117.109 128.619 1.00 105.98 ? 291 PHE C CD1 1 
ATOM   5624 C CD2 . PHE C 1 291 ? 93.682  118.452 128.850 1.00 105.98 ? 291 PHE C CD2 1 
ATOM   5625 C CE1 . PHE C 1 291 ? 94.837  115.999 128.435 1.00 105.98 ? 291 PHE C CE1 1 
ATOM   5626 C CE2 . PHE C 1 291 ? 92.890  117.349 128.667 1.00 105.98 ? 291 PHE C CE2 1 
ATOM   5627 C CZ  . PHE C 1 291 ? 93.469  116.120 128.459 1.00 105.98 ? 291 PHE C CZ  1 
ATOM   5628 N N   . SER C 1 292 ? 96.055  121.810 126.937 1.00 110.21 ? 292 SER C N   1 
ATOM   5629 C CA  . SER C 1 292 ? 95.437  122.581 125.867 1.00 110.21 ? 292 SER C CA  1 
ATOM   5630 C C   . SER C 1 292 ? 96.341  122.734 124.649 1.00 110.21 ? 292 SER C C   1 
ATOM   5631 O O   . SER C 1 292 ? 95.854  122.641 123.522 1.00 110.21 ? 292 SER C O   1 
ATOM   5632 C CB  . SER C 1 292 ? 95.014  123.946 126.390 1.00 110.21 ? 292 SER C CB  1 
ATOM   5633 O OG  . SER C 1 292 ? 94.155  123.785 127.503 1.00 110.21 ? 292 SER C OG  1 
ATOM   5634 N N   . LYS C 1 293 ? 97.643  122.953 124.835 1.00 112.43 ? 293 LYS C N   1 
ATOM   5635 C CA  . LYS C 1 293 ? 98.514  123.112 123.675 1.00 112.43 ? 293 LYS C CA  1 
ATOM   5636 C C   . LYS C 1 293 ? 98.647  121.813 122.901 1.00 112.43 ? 293 LYS C C   1 
ATOM   5637 O O   . LYS C 1 293 ? 98.731  121.829 121.668 1.00 112.43 ? 293 LYS C O   1 
ATOM   5638 C CB  . LYS C 1 293 ? 99.891  123.618 124.093 1.00 112.43 ? 293 LYS C CB  1 
ATOM   5639 C CG  . LYS C 1 293 ? 99.892  125.034 124.607 1.00 112.43 ? 293 LYS C CG  1 
ATOM   5640 C CD  . LYS C 1 293 ? 101.276 125.443 125.070 1.00 112.43 ? 293 LYS C CD  1 
ATOM   5641 C CE  . LYS C 1 293 ? 102.227 125.618 123.905 1.00 112.43 ? 293 LYS C CE  1 
ATOM   5642 N NZ  . LYS C 1 293 ? 101.845 126.790 123.071 1.00 112.43 ? 293 LYS C NZ  1 
ATOM   5643 N N   . THR C 1 294 ? 98.685  120.672 123.593 1.00 113.59 ? 294 THR C N   1 
ATOM   5644 C CA  . THR C 1 294 ? 98.808  119.424 122.852 1.00 113.59 ? 294 THR C CA  1 
ATOM   5645 C C   . THR C 1 294 ? 97.502  119.059 122.163 1.00 113.59 ? 294 THR C C   1 
ATOM   5646 O O   . THR C 1 294 ? 97.523  118.451 121.086 1.00 113.59 ? 294 THR C O   1 
ATOM   5647 C CB  . THR C 1 294 ? 99.277  118.291 123.757 1.00 113.59 ? 294 THR C CB  1 
ATOM   5648 O OG1 . THR C 1 294 ? 99.561  117.151 122.948 1.00 113.59 ? 294 THR C OG1 1 
ATOM   5649 C CG2 . THR C 1 294 ? 98.216  117.914 124.752 1.00 113.59 ? 294 THR C CG2 1 
ATOM   5650 N N   . LEU C 1 295 ? 96.358  119.443 122.740 1.00 115.02 ? 295 LEU C N   1 
ATOM   5651 C CA  . LEU C 1 295 ? 95.109  119.295 122.001 1.00 115.02 ? 295 LEU C CA  1 
ATOM   5652 C C   . LEU C 1 295 ? 95.025  120.283 120.847 1.00 115.02 ? 295 LEU C C   1 
ATOM   5653 O O   . LEU C 1 295 ? 94.290  120.048 119.887 1.00 115.02 ? 295 LEU C O   1 
ATOM   5654 C CB  . LEU C 1 295 ? 93.914  119.453 122.932 1.00 115.02 ? 295 LEU C CB  1 
ATOM   5655 C CG  . LEU C 1 295 ? 93.356  118.130 123.449 1.00 115.02 ? 295 LEU C CG  1 
ATOM   5656 C CD1 . LEU C 1 295 ? 92.750  117.366 122.299 1.00 115.02 ? 295 LEU C CD1 1 
ATOM   5657 C CD2 . LEU C 1 295 ? 94.436  117.301 124.106 1.00 115.02 ? 295 LEU C CD2 1 
ATOM   5658 N N   . ASN C 1 296 ? 95.738  121.404 120.933 1.00 117.61 ? 296 ASN C N   1 
ATOM   5659 C CA  . ASN C 1 296 ? 95.839  122.321 119.807 1.00 117.61 ? 296 ASN C CA  1 
ATOM   5660 C C   . ASN C 1 296 ? 96.665  121.763 118.660 1.00 117.61 ? 296 ASN C C   1 
ATOM   5661 O O   . ASN C 1 296 ? 96.206  121.784 117.514 1.00 117.61 ? 296 ASN C O   1 
ATOM   5662 C CB  . ASN C 1 296 ? 96.452  123.644 120.260 1.00 117.61 ? 296 ASN C CB  1 
ATOM   5663 C CG  . ASN C 1 296 ? 96.459  124.685 119.168 1.00 117.61 ? 296 ASN C CG  1 
ATOM   5664 O OD1 . ASN C 1 296 ? 97.505  125.231 118.823 1.00 117.61 ? 296 ASN C OD1 1 
ATOM   5665 N ND2 . ASN C 1 296 ? 95.289  124.972 118.616 1.00 117.61 ? 296 ASN C ND2 1 
ATOM   5666 N N   . TYR C 1 297 ? 97.864  121.259 118.940 1.00 122.73 ? 297 TYR C N   1 
ATOM   5667 C CA  . TYR C 1 297 ? 98.696  120.642 117.914 1.00 122.73 ? 297 TYR C CA  1 
ATOM   5668 C C   . TYR C 1 297 ? 98.226  119.237 117.568 1.00 122.73 ? 297 TYR C C   1 
ATOM   5669 O O   . TYR C 1 297 ? 98.846  118.569 116.734 1.00 122.73 ? 297 TYR C O   1 
ATOM   5670 C CB  . TYR C 1 297 ? 100.164 120.609 118.341 1.00 122.73 ? 297 TYR C CB  1 
ATOM   5671 C CG  . TYR C 1 297 ? 100.748 121.924 118.781 1.00 122.73 ? 297 TYR C CG  1 
ATOM   5672 C CD1 . TYR C 1 297 ? 101.304 122.066 120.042 1.00 122.73 ? 297 TYR C CD1 1 
ATOM   5673 C CD2 . TYR C 1 297 ? 100.765 123.022 117.933 1.00 122.73 ? 297 TYR C CD2 1 
ATOM   5674 C CE1 . TYR C 1 297 ? 101.851 123.263 120.453 1.00 122.73 ? 297 TYR C CE1 1 
ATOM   5675 C CE2 . TYR C 1 297 ? 101.310 124.227 118.337 1.00 122.73 ? 297 TYR C CE2 1 
ATOM   5676 C CZ  . TYR C 1 297 ? 101.850 124.338 119.599 1.00 122.73 ? 297 TYR C CZ  1 
ATOM   5677 O OH  . TYR C 1 297 ? 102.397 125.525 120.013 1.00 122.73 ? 297 TYR C OH  1 
ATOM   5678 N N   . LEU C 1 298 ? 97.156  118.774 118.208 1.00 123.50 ? 298 LEU C N   1 
ATOM   5679 C CA  . LEU C 1 298 ? 96.472  117.546 117.834 1.00 123.50 ? 298 LEU C CA  1 
ATOM   5680 C C   . LEU C 1 298 ? 94.988  117.881 117.735 1.00 123.50 ? 298 LEU C C   1 
ATOM   5681 O O   . LEU C 1 298 ? 94.142  117.185 118.301 1.00 123.50 ? 298 LEU C O   1 
ATOM   5682 C CB  . LEU C 1 298 ? 96.769  116.449 118.860 1.00 123.50 ? 298 LEU C CB  1 
ATOM   5683 C CG  . LEU C 1 298 ? 96.464  114.972 118.607 1.00 123.50 ? 298 LEU C CG  1 
ATOM   5684 C CD1 . LEU C 1 298 ? 97.592  114.149 119.188 1.00 123.50 ? 298 LEU C CD1 1 
ATOM   5685 C CD2 . LEU C 1 298 ? 95.159  114.544 119.254 1.00 123.50 ? 298 LEU C CD2 1 
ATOM   5686 N N   . ASP C 1 299 ? 94.678  118.967 117.021 1.00 125.92 ? 299 ASP C N   1 
ATOM   5687 C CA  . ASP C 1 299 ? 93.395  119.664 117.100 1.00 125.92 ? 299 ASP C CA  1 
ATOM   5688 C C   . ASP C 1 299 ? 92.156  118.773 117.102 1.00 125.92 ? 299 ASP C C   1 
ATOM   5689 O O   . ASP C 1 299 ? 92.114  117.723 116.453 1.00 125.92 ? 299 ASP C O   1 
ATOM   5690 C CB  . ASP C 1 299 ? 93.298  120.701 115.977 1.00 125.92 ? 299 ASP C CB  1 
ATOM   5691 C CG  . ASP C 1 299 ? 93.341  120.087 114.596 1.00 125.92 ? 299 ASP C CG  1 
ATOM   5692 O OD1 . ASP C 1 299 ? 93.492  118.854 114.477 1.00 125.92 ? 299 ASP C OD1 1 
ATOM   5693 O OD2 . ASP C 1 299 ? 93.219  120.851 113.617 1.00 125.92 ? 299 ASP C OD2 1 
ATOM   5694 N N   . SER C 1 300 ? 91.151  119.193 117.870 1.00 122.47 ? 300 SER C N   1 
ATOM   5695 C CA  . SER C 1 300 ? 89.871  118.504 117.963 1.00 122.47 ? 300 SER C CA  1 
ATOM   5696 C C   . SER C 1 300 ? 88.829  119.436 118.563 1.00 122.47 ? 300 SER C C   1 
ATOM   5697 O O   . SER C 1 300 ? 89.121  120.600 118.856 1.00 122.47 ? 300 SER C O   1 
ATOM   5698 C CB  . SER C 1 300 ? 89.997  117.235 118.804 1.00 122.47 ? 300 SER C CB  1 
ATOM   5699 O OG  . SER C 1 300 ? 90.181  117.553 120.170 1.00 122.47 ? 300 SER C OG  1 
ATOM   5700 N N   . GLY C 1 301 ? 87.613  118.937 118.759 1.00 123.52 ? 301 GLY C N   1 
ATOM   5701 C CA  . GLY C 1 301 ? 86.569  119.727 119.378 1.00 123.52 ? 301 GLY C CA  1 
ATOM   5702 C C   . GLY C 1 301 ? 86.884  120.081 120.815 1.00 123.52 ? 301 GLY C C   1 
ATOM   5703 O O   . GLY C 1 301 ? 86.462  121.127 121.314 1.00 123.52 ? 301 GLY C O   1 
ATOM   5704 N N   . LEU C 1 302 ? 87.618  119.203 121.493 1.00 122.92 ? 302 LEU C N   1 
ATOM   5705 C CA  . LEU C 1 302 ? 87.938  119.375 122.905 1.00 122.92 ? 302 LEU C CA  1 
ATOM   5706 C C   . LEU C 1 302 ? 88.847  120.571 123.153 1.00 122.92 ? 302 LEU C C   1 
ATOM   5707 O O   . LEU C 1 302 ? 88.907  121.083 124.274 1.00 122.92 ? 302 LEU C O   1 
ATOM   5708 C CB  . LEU C 1 302 ? 88.591  118.104 123.449 1.00 122.92 ? 302 LEU C CB  1 
ATOM   5709 C CG  . LEU C 1 302 ? 87.706  116.860 123.457 1.00 122.92 ? 302 LEU C CG  1 
ATOM   5710 C CD1 . LEU C 1 302 ? 88.517  115.633 123.829 1.00 122.92 ? 302 LEU C CD1 1 
ATOM   5711 C CD2 . LEU C 1 302 ? 86.546  117.049 124.420 1.00 122.92 ? 302 LEU C CD2 1 
ATOM   5712 N N   . ALA C 1 303 ? 89.560  121.015 122.121 1.00 121.47 ? 303 ALA C N   1 
ATOM   5713 C CA  . ALA C 1 303 ? 90.589  122.035 122.274 1.00 121.47 ? 303 ALA C CA  1 
ATOM   5714 C C   . ALA C 1 303 ? 90.062  123.306 122.928 1.00 121.47 ? 303 ALA C C   1 
ATOM   5715 O O   . ALA C 1 303 ? 90.654  123.805 123.891 1.00 121.47 ? 303 ALA C O   1 
ATOM   5716 C CB  . ALA C 1 303 ? 91.199  122.366 120.912 1.00 121.47 ? 303 ALA C CB  1 
ATOM   5717 N N   . PHE C 1 304 ? 88.947  123.830 122.420 1.00 124.07 ? 304 PHE C N   1 
ATOM   5718 C CA  . PHE C 1 304 ? 88.391  125.083 122.913 1.00 124.07 ? 304 PHE C CA  1 
ATOM   5719 C C   . PHE C 1 304 ? 87.975  124.999 124.375 1.00 124.07 ? 304 PHE C C   1 
ATOM   5720 O O   . PHE C 1 304 ? 88.248  125.921 125.152 1.00 124.07 ? 304 PHE C O   1 
ATOM   5721 C CB  . PHE C 1 304 ? 87.185  125.493 122.065 1.00 124.07 ? 304 PHE C CB  1 
ATOM   5722 C CG  . PHE C 1 304 ? 87.440  125.450 120.588 1.00 124.07 ? 304 PHE C CG  1 
ATOM   5723 C CD1 . PHE C 1 304 ? 88.579  126.022 120.051 1.00 124.07 ? 304 PHE C CD1 1 
ATOM   5724 C CD2 . PHE C 1 304 ? 86.538  124.839 119.735 1.00 124.07 ? 304 PHE C CD2 1 
ATOM   5725 C CE1 . PHE C 1 304 ? 88.814  125.983 118.692 1.00 124.07 ? 304 PHE C CE1 1 
ATOM   5726 C CE2 . PHE C 1 304 ? 86.769  124.795 118.377 1.00 124.07 ? 304 PHE C CE2 1 
ATOM   5727 C CZ  . PHE C 1 304 ? 87.908  125.368 117.854 1.00 124.07 ? 304 PHE C CZ  1 
ATOM   5728 N N   . PHE C 1 305 ? 87.318  123.904 124.761 1.00 124.00 ? 305 PHE C N   1 
ATOM   5729 C CA  . PHE C 1 305 ? 86.835  123.772 126.130 1.00 124.00 ? 305 PHE C CA  1 
ATOM   5730 C C   . PHE C 1 305 ? 87.997  123.674 127.108 1.00 124.00 ? 305 PHE C C   1 
ATOM   5731 O O   . PHE C 1 305 ? 88.007  124.338 128.155 1.00 124.00 ? 305 PHE C O   1 
ATOM   5732 C CB  . PHE C 1 305 ? 85.930  122.546 126.239 1.00 124.00 ? 305 PHE C CB  1 
ATOM   5733 C CG  . PHE C 1 305 ? 84.765  122.562 125.284 1.00 124.00 ? 305 PHE C CG  1 
ATOM   5734 C CD1 . PHE C 1 305 ? 84.310  123.751 124.732 1.00 124.00 ? 305 PHE C CD1 1 
ATOM   5735 C CD2 . PHE C 1 305 ? 84.135  121.382 124.925 1.00 124.00 ? 305 PHE C CD2 1 
ATOM   5736 C CE1 . PHE C 1 305 ? 83.246  123.763 123.851 1.00 124.00 ? 305 PHE C CE1 1 
ATOM   5737 C CE2 . PHE C 1 305 ? 83.068  121.390 124.046 1.00 124.00 ? 305 PHE C CE2 1 
ATOM   5738 C CZ  . PHE C 1 305 ? 82.624  122.583 123.509 1.00 124.00 ? 305 PHE C CZ  1 
ATOM   5739 N N   . SER C 1 306 ? 88.992  122.854 126.770 1.00 117.60 ? 306 SER C N   1 
ATOM   5740 C CA  . SER C 1 306 ? 90.175  122.741 127.612 1.00 117.60 ? 306 SER C CA  1 
ATOM   5741 C C   . SER C 1 306 ? 90.889  124.076 127.720 1.00 117.60 ? 306 SER C C   1 
ATOM   5742 O O   . SER C 1 306 ? 91.366  124.443 128.796 1.00 117.60 ? 306 SER C O   1 
ATOM   5743 C CB  . SER C 1 306 ? 91.118  121.674 127.060 1.00 117.60 ? 306 SER C CB  1 
ATOM   5744 O OG  . SER C 1 306 ? 90.492  120.405 127.032 1.00 117.60 ? 306 SER C OG  1 
ATOM   5745 N N   . PHE C 1 307 ? 90.970  124.823 126.619 1.00 113.92 ? 307 PHE C N   1 
ATOM   5746 C CA  . PHE C 1 307 ? 91.667  126.100 126.676 1.00 113.92 ? 307 PHE C CA  1 
ATOM   5747 C C   . PHE C 1 307 ? 90.916  127.103 127.541 1.00 113.92 ? 307 PHE C C   1 
ATOM   5748 O O   . PHE C 1 307 ? 91.530  127.877 128.280 1.00 113.92 ? 307 PHE C O   1 
ATOM   5749 C CB  . PHE C 1 307 ? 91.887  126.658 125.274 1.00 113.92 ? 307 PHE C CB  1 
ATOM   5750 C CG  . PHE C 1 307 ? 92.728  127.899 125.252 1.00 113.92 ? 307 PHE C CG  1 
ATOM   5751 C CD1 . PHE C 1 307 ? 92.148  129.148 125.356 1.00 113.92 ? 307 PHE C CD1 1 
ATOM   5752 C CD2 . PHE C 1 307 ? 94.102  127.812 125.152 1.00 113.92 ? 307 PHE C CD2 1 
ATOM   5753 C CE1 . PHE C 1 307 ? 92.920  130.282 125.344 1.00 113.92 ? 307 PHE C CE1 1 
ATOM   5754 C CE2 . PHE C 1 307 ? 94.878  128.943 125.141 1.00 113.92 ? 307 PHE C CE2 1 
ATOM   5755 C CZ  . PHE C 1 307 ? 94.286  130.181 125.240 1.00 113.92 ? 307 PHE C CZ  1 
ATOM   5756 N N   . ALA C 1 308 ? 89.586  127.126 127.449 1.00 112.56 ? 308 ALA C N   1 
ATOM   5757 C CA  . ALA C 1 308 ? 88.825  128.044 128.295 1.00 112.56 ? 308 ALA C CA  1 
ATOM   5758 C C   . ALA C 1 308 ? 88.971  127.695 129.772 1.00 112.56 ? 308 ALA C C   1 
ATOM   5759 O O   . ALA C 1 308 ? 89.130  128.595 130.613 1.00 112.56 ? 308 ALA C O   1 
ATOM   5760 C CB  . ALA C 1 308 ? 87.355  128.046 127.886 1.00 112.56 ? 308 ALA C CB  1 
ATOM   5761 N N   . ILE C 1 309 ? 88.925  126.407 130.109 1.00 108.66 ? 309 ILE C N   1 
ATOM   5762 C CA  . ILE C 1 309 ? 89.212  126.014 131.480 1.00 108.66 ? 309 ILE C CA  1 
ATOM   5763 C C   . ILE C 1 309 ? 90.621  126.417 131.880 1.00 108.66 ? 309 ILE C C   1 
ATOM   5764 O O   . ILE C 1 309 ? 90.846  126.828 133.024 1.00 108.66 ? 309 ILE C O   1 
ATOM   5765 C CB  . ILE C 1 309 ? 88.999  124.504 131.665 1.00 108.66 ? 309 ILE C CB  1 
ATOM   5766 C CG1 . ILE C 1 309 ? 87.556  124.144 131.320 1.00 108.66 ? 309 ILE C CG1 1 
ATOM   5767 C CG2 . ILE C 1 309 ? 89.338  124.081 133.084 1.00 108.66 ? 309 ILE C CG2 1 
ATOM   5768 C CD1 . ILE C 1 309 ? 86.542  124.835 132.198 1.00 108.66 ? 309 ILE C CD1 1 
ATOM   5769 N N   . PHE C 1 310 ? 91.580  126.315 130.961 1.00 104.18 ? 310 PHE C N   1 
ATOM   5770 C CA  . PHE C 1 310 ? 92.932  126.759 131.259 1.00 104.18 ? 310 PHE C CA  1 
ATOM   5771 C C   . PHE C 1 310 ? 92.953  128.238 131.578 1.00 104.18 ? 310 PHE C C   1 
ATOM   5772 O O   . PHE C 1 310 ? 93.677  128.670 132.471 1.00 104.18 ? 310 PHE C O   1 
ATOM   5773 C CB  . PHE C 1 310 ? 93.870  126.483 130.092 1.00 104.18 ? 310 PHE C CB  1 
ATOM   5774 C CG  . PHE C 1 310 ? 95.092  127.352 130.103 1.00 104.18 ? 310 PHE C CG  1 
ATOM   5775 C CD1 . PHE C 1 310 ? 96.042  127.220 131.100 1.00 104.18 ? 310 PHE C CD1 1 
ATOM   5776 C CD2 . PHE C 1 310 ? 95.276  128.328 129.140 1.00 104.18 ? 310 PHE C CD2 1 
ATOM   5777 C CE1 . PHE C 1 310 ? 97.162  128.026 131.120 1.00 104.18 ? 310 PHE C CE1 1 
ATOM   5778 C CE2 . PHE C 1 310 ? 96.393  129.139 129.158 1.00 104.18 ? 310 PHE C CE2 1 
ATOM   5779 C CZ  . PHE C 1 310 ? 97.336  128.987 130.145 1.00 104.18 ? 310 PHE C CZ  1 
ATOM   5780 N N   . VAL C 1 311 ? 92.195  129.036 130.830 1.00 102.51 ? 311 VAL C N   1 
ATOM   5781 C CA  . VAL C 1 311 ? 92.162  130.473 131.089 1.00 102.51 ? 311 VAL C CA  1 
ATOM   5782 C C   . VAL C 1 311 ? 91.598  130.750 132.473 1.00 102.51 ? 311 VAL C C   1 
ATOM   5783 O O   . VAL C 1 311 ? 92.153  131.547 133.240 1.00 102.51 ? 311 VAL C O   1 
ATOM   5784 C CB  . VAL C 1 311 ? 91.357  131.202 130.003 1.00 102.51 ? 311 VAL C CB  1 
ATOM   5785 C CG1 . VAL C 1 311 ? 91.239  132.667 130.345 1.00 102.51 ? 311 VAL C CG1 1 
ATOM   5786 C CG2 . VAL C 1 311 ? 92.033  131.048 128.667 1.00 102.51 ? 311 VAL C CG2 1 
ATOM   5787 N N   . VAL C 1 312 ? 90.494  130.089 132.820 1.00 100.16 ? 312 VAL C N   1 
ATOM   5788 C CA  . VAL C 1 312 ? 89.902  130.290 134.141 1.00 100.16 ? 312 VAL C CA  1 
ATOM   5789 C C   . VAL C 1 312 ? 90.905  129.940 135.231 1.00 100.16 ? 312 VAL C C   1 
ATOM   5790 O O   . VAL C 1 312 ? 91.153  130.727 136.156 1.00 100.16 ? 312 VAL C O   1 
ATOM   5791 C CB  . VAL C 1 312 ? 88.612  129.466 134.283 1.00 100.16 ? 312 VAL C CB  1 
ATOM   5792 C CG1 . VAL C 1 312 ? 88.232  129.336 135.741 1.00 100.16 ? 312 VAL C CG1 1 
ATOM   5793 C CG2 . VAL C 1 312 ? 87.493  130.115 133.500 1.00 100.16 ? 312 VAL C CG2 1 
ATOM   5794 N N   . ALA C 1 313 ? 91.509  128.756 135.129 1.00 95.79  ? 313 ALA C N   1 
ATOM   5795 C CA  . ALA C 1 313 ? 92.434  128.311 136.160 1.00 95.79  ? 313 ALA C CA  1 
ATOM   5796 C C   . ALA C 1 313 ? 93.694  129.157 136.191 1.00 95.79  ? 313 ALA C C   1 
ATOM   5797 O O   . ALA C 1 313 ? 94.254  129.378 137.263 1.00 95.79  ? 313 ALA C O   1 
ATOM   5798 C CB  . ALA C 1 313 ? 92.785  126.842 135.959 1.00 95.79  ? 313 ALA C CB  1 
ATOM   5799 N N   . TRP C 1 314 ? 94.155  129.639 135.040 1.00 94.91  ? 314 TRP C N   1 
ATOM   5800 C CA  . TRP C 1 314 ? 95.322  130.507 135.014 1.00 94.91  ? 314 TRP C CA  1 
ATOM   5801 C C   . TRP C 1 314 ? 95.036  131.796 135.755 1.00 94.91  ? 314 TRP C C   1 
ATOM   5802 O O   . TRP C 1 314 ? 95.783  132.169 136.666 1.00 94.91  ? 314 TRP C O   1 
ATOM   5803 C CB  . TRP C 1 314 ? 95.733  130.795 133.572 1.00 94.91  ? 314 TRP C CB  1 
ATOM   5804 C CG  . TRP C 1 314 ? 96.798  131.840 133.421 1.00 94.91  ? 314 TRP C CG  1 
ATOM   5805 C CD1 . TRP C 1 314 ? 96.653  133.184 133.550 1.00 94.91  ? 314 TRP C CD1 1 
ATOM   5806 C CD2 . TRP C 1 314 ? 98.169  131.617 133.093 1.00 94.91  ? 314 TRP C CD2 1 
ATOM   5807 N NE1 . TRP C 1 314 ? 97.847  133.813 133.335 1.00 94.91  ? 314 TRP C NE1 1 
ATOM   5808 C CE2 . TRP C 1 314 ? 98.796  132.871 133.051 1.00 94.91  ? 314 TRP C CE2 1 
ATOM   5809 C CE3 . TRP C 1 314 ? 98.929  130.475 132.837 1.00 94.91  ? 314 TRP C CE3 1 
ATOM   5810 C CZ2 . TRP C 1 314 ? 100.143 133.017 132.763 1.00 94.91  ? 314 TRP C CZ2 1 
ATOM   5811 C CZ3 . TRP C 1 314 ? 100.266 130.622 132.549 1.00 94.91  ? 314 TRP C CZ3 1 
ATOM   5812 C CH2 . TRP C 1 314 ? 100.860 131.882 132.515 1.00 94.91  ? 314 TRP C CH2 1 
ATOM   5813 N N   . ILE C 1 315 ? 93.938  132.470 135.396 1.00 94.86  ? 315 ILE C N   1 
ATOM   5814 C CA  . ILE C 1 315 ? 93.532  133.669 136.126 1.00 94.86  ? 315 ILE C CA  1 
ATOM   5815 C C   . ILE C 1 315 ? 93.533  133.393 137.616 1.00 94.86  ? 315 ILE C C   1 
ATOM   5816 O O   . ILE C 1 315 ? 94.356  133.942 138.361 1.00 94.86  ? 315 ILE C O   1 
ATOM   5817 C CB  . ILE C 1 315 ? 92.148  134.152 135.657 1.00 94.86  ? 315 ILE C CB  1 
ATOM   5818 C CG1 . ILE C 1 315 ? 92.159  134.471 134.168 1.00 94.86  ? 315 ILE C CG1 1 
ATOM   5819 C CG2 . ILE C 1 315 ? 91.704  135.354 136.463 1.00 94.86  ? 315 ILE C CG2 1 
ATOM   5820 C CD1 . ILE C 1 315 ? 93.113  135.555 133.814 1.00 94.86  ? 315 ILE C CD1 1 
ATOM   5821 N N   . TYR C 1 316 ? 92.692  132.447 138.050 1.00 92.56  ? 316 TYR C N   1 
ATOM   5822 C CA  . TYR C 1 316 ? 92.549  132.195 139.479 1.00 92.56  ? 316 TYR C CA  1 
ATOM   5823 C C   . TYR C 1 316 ? 93.889  131.861 140.111 1.00 92.56  ? 316 TYR C C   1 
ATOM   5824 O O   . TYR C 1 316 ? 94.471  132.696 140.810 1.00 92.56  ? 316 TYR C O   1 
ATOM   5825 C CB  . TYR C 1 316 ? 91.558  131.066 139.728 1.00 92.56  ? 316 TYR C CB  1 
ATOM   5826 C CG  . TYR C 1 316 ? 91.553  130.621 141.166 1.00 92.56  ? 316 TYR C CG  1 
ATOM   5827 C CD1 . TYR C 1 316 ? 91.008  131.424 142.153 1.00 92.56  ? 316 TYR C CD1 1 
ATOM   5828 C CD2 . TYR C 1 316 ? 92.101  129.409 141.539 1.00 92.56  ? 316 TYR C CD2 1 
ATOM   5829 C CE1 . TYR C 1 316 ? 91.001  131.029 143.470 1.00 92.56  ? 316 TYR C CE1 1 
ATOM   5830 C CE2 . TYR C 1 316 ? 92.100  129.006 142.858 1.00 92.56  ? 316 TYR C CE2 1 
ATOM   5831 C CZ  . TYR C 1 316 ? 91.549  129.821 143.818 1.00 92.56  ? 316 TYR C CZ  1 
ATOM   5832 O OH  . TYR C 1 316 ? 91.544  129.428 145.134 1.00 92.56  ? 316 TYR C OH  1 
ATOM   5833 N N   . LEU C 1 317 ? 94.450  130.697 139.777 1.00 90.05  ? 317 LEU C N   1 
ATOM   5834 C CA  . LEU C 1 317 ? 95.670  130.251 140.433 1.00 90.05  ? 317 LEU C CA  1 
ATOM   5835 C C   . LEU C 1 317 ? 96.755  131.300 140.325 1.00 90.05  ? 317 LEU C C   1 
ATOM   5836 O O   . LEU C 1 317 ? 97.035  132.001 141.301 1.00 90.05  ? 317 LEU C O   1 
ATOM   5837 C CB  . LEU C 1 317 ? 96.157  128.941 139.821 1.00 90.05  ? 317 LEU C CB  1 
ATOM   5838 C CG  . LEU C 1 317 ? 95.356  127.676 140.093 1.00 90.05  ? 317 LEU C CG  1 
ATOM   5839 C CD1 . LEU C 1 317 ? 95.828  126.583 139.173 1.00 90.05  ? 317 LEU C CD1 1 
ATOM   5840 C CD2 . LEU C 1 317 ? 95.513  127.254 141.532 1.00 90.05  ? 317 LEU C CD2 1 
ATOM   5841 N N   . ARG C 1 318 ? 97.284  131.519 139.125 1.00 91.59  ? 318 ARG C N   1 
ATOM   5842 C CA  . ARG C 1 318 ? 98.453  132.373 139.059 1.00 91.59  ? 318 ARG C CA  1 
ATOM   5843 C C   . ARG C 1 318 ? 98.146  133.767 139.571 1.00 91.59  ? 318 ARG C C   1 
ATOM   5844 O O   . ARG C 1 318 ? 98.683  134.166 140.608 1.00 91.59  ? 318 ARG C O   1 
ATOM   5845 C CB  . ARG C 1 318 ? 99.006  132.411 137.643 1.00 91.59  ? 318 ARG C CB  1 
ATOM   5846 C CG  . ARG C 1 318 ? 99.988  131.286 137.363 1.00 91.59  ? 318 ARG C CG  1 
ATOM   5847 C CD  . ARG C 1 318 ? 100.392 131.300 135.918 1.00 91.59  ? 318 ARG C CD  1 
ATOM   5848 N NE  . ARG C 1 318 ? 101.324 130.240 135.559 1.00 91.59  ? 318 ARG C NE  1 
ATOM   5849 C CZ  . ARG C 1 318 ? 102.621 130.427 135.351 1.00 91.59  ? 318 ARG C CZ  1 
ATOM   5850 N NH1 . ARG C 1 318 ? 103.142 131.639 135.468 1.00 91.59  ? 318 ARG C NH1 1 
ATOM   5851 N NH2 . ARG C 1 318 ? 103.397 129.406 135.020 1.00 91.59  ? 318 ARG C NH2 1 
ATOM   5852 N N   . HIS C 1 319 ? 97.243  134.504 138.925 1.00 93.82  ? 319 HIS C N   1 
ATOM   5853 C CA  . HIS C 1 319 ? 97.152  135.904 139.300 1.00 93.82  ? 319 HIS C CA  1 
ATOM   5854 C C   . HIS C 1 319 ? 96.546  136.090 140.687 1.00 93.82  ? 319 HIS C C   1 
ATOM   5855 O O   . HIS C 1 319 ? 97.139  136.773 141.527 1.00 93.82  ? 319 HIS C O   1 
ATOM   5856 C CB  . HIS C 1 319 ? 96.381  136.671 138.236 1.00 93.82  ? 319 HIS C CB  1 
ATOM   5857 C CG  . HIS C 1 319 ? 97.227  137.045 137.061 1.00 93.82  ? 319 HIS C CG  1 
ATOM   5858 N ND1 . HIS C 1 319 ? 97.519  136.161 136.047 1.00 93.82  ? 319 HIS C ND1 1 
ATOM   5859 C CD2 . HIS C 1 319 ? 97.877  138.193 136.759 1.00 93.82  ? 319 HIS C CD2 1 
ATOM   5860 C CE1 . HIS C 1 319 ? 98.297  136.754 135.159 1.00 93.82  ? 319 HIS C CE1 1 
ATOM   5861 N NE2 . HIS C 1 319 ? 98.528  137.987 135.567 1.00 93.82  ? 319 HIS C NE2 1 
ATOM   5862 N N   . TYR C 1 320 ? 95.406  135.463 140.979 1.00 88.37  ? 320 TYR C N   1 
ATOM   5863 C CA  . TYR C 1 320 ? 94.808  135.713 142.278 1.00 88.37  ? 320 TYR C CA  1 
ATOM   5864 C C   . TYR C 1 320 ? 95.638  135.146 143.420 1.00 88.37  ? 320 TYR C C   1 
ATOM   5865 O O   . TYR C 1 320 ? 95.865  135.847 144.410 1.00 88.37  ? 320 TYR C O   1 
ATOM   5866 C CB  . TYR C 1 320 ? 93.399  135.132 142.333 1.00 88.37  ? 320 TYR C CB  1 
ATOM   5867 C CG  . TYR C 1 320 ? 92.784  135.183 143.703 1.00 88.37  ? 320 TYR C CG  1 
ATOM   5868 C CD1 . TYR C 1 320 ? 92.272  134.045 144.292 1.00 88.37  ? 320 TYR C CD1 1 
ATOM   5869 C CD2 . TYR C 1 320 ? 92.717  136.372 144.408 1.00 88.37  ? 320 TYR C CD2 1 
ATOM   5870 C CE1 . TYR C 1 320 ? 91.711  134.083 145.542 1.00 88.37  ? 320 TYR C CE1 1 
ATOM   5871 C CE2 . TYR C 1 320 ? 92.159  136.421 145.659 1.00 88.37  ? 320 TYR C CE2 1 
ATOM   5872 C CZ  . TYR C 1 320 ? 91.656  135.272 146.223 1.00 88.37  ? 320 TYR C CZ  1 
ATOM   5873 O OH  . TYR C 1 320 ? 91.094  135.307 147.477 1.00 88.37  ? 320 TYR C OH  1 
ATOM   5874 N N   . ILE C 1 321 ? 96.085  133.894 143.335 1.00 86.99  ? 321 ILE C N   1 
ATOM   5875 C CA  . ILE C 1 321 ? 96.855  133.332 144.428 1.00 86.99  ? 321 ILE C CA  1 
ATOM   5876 C C   . ILE C 1 321 ? 98.191  134.040 144.614 1.00 86.99  ? 321 ILE C C   1 
ATOM   5877 O O   . ILE C 1 321 ? 98.564  134.346 145.746 1.00 86.99  ? 321 ILE C O   1 
ATOM   5878 C CB  . ILE C 1 321 ? 97.049  131.827 144.208 1.00 86.99  ? 321 ILE C CB  1 
ATOM   5879 C CG1 . ILE C 1 321 ? 95.699  131.120 144.232 1.00 86.99  ? 321 ILE C CG1 1 
ATOM   5880 C CG2 . ILE C 1 321 ? 97.949  131.252 145.265 1.00 86.99  ? 321 ILE C CG2 1 
ATOM   5881 C CD1 . ILE C 1 321 ? 94.970  131.265 145.528 1.00 86.99  ? 321 ILE C CD1 1 
ATOM   5882 N N   . ASN C 1 322 ? 98.930  134.332 143.543 1.00 84.30  ? 322 ASN C N   1 
ATOM   5883 C CA  . ASN C 1 322 ? 100.195 135.020 143.745 1.00 84.30  ? 322 ASN C CA  1 
ATOM   5884 C C   . ASN C 1 322 ? 99.982  136.446 144.238 1.00 84.30  ? 322 ASN C C   1 
ATOM   5885 O O   . ASN C 1 322 ? 100.783 136.952 145.031 1.00 84.30  ? 322 ASN C O   1 
ATOM   5886 C CB  . ASN C 1 322 ? 101.011 135.001 142.454 1.00 84.30  ? 322 ASN C CB  1 
ATOM   5887 C CG  . ASN C 1 322 ? 101.570 133.626 142.139 1.00 84.30  ? 322 ASN C CG  1 
ATOM   5888 O OD1 . ASN C 1 322 ? 101.055 132.614 142.607 1.00 84.30  ? 322 ASN C OD1 1 
ATOM   5889 N ND2 . ASN C 1 322 ? 102.627 133.584 141.342 1.00 84.30  ? 322 ASN C ND2 1 
ATOM   5890 N N   . LEU C 1 323 ? 98.900  137.110 143.820 1.00 87.83  ? 323 LEU C N   1 
ATOM   5891 C CA  . LEU C 1 323 ? 98.650  138.452 144.327 1.00 87.83  ? 323 LEU C CA  1 
ATOM   5892 C C   . LEU C 1 323 ? 98.263  138.436 145.798 1.00 87.83  ? 323 LEU C C   1 
ATOM   5893 O O   . LEU C 1 323 ? 98.706  139.301 146.563 1.00 87.83  ? 323 LEU C O   1 
ATOM   5894 C CB  . LEU C 1 323 ? 97.574  139.139 143.492 1.00 87.83  ? 323 LEU C CB  1 
ATOM   5895 C CG  . LEU C 1 323 ? 98.081  139.766 142.192 1.00 87.83  ? 323 LEU C CG  1 
ATOM   5896 C CD1 . LEU C 1 323 ? 96.922  140.163 141.300 1.00 87.83  ? 323 LEU C CD1 1 
ATOM   5897 C CD2 . LEU C 1 323 ? 98.959  140.964 142.479 1.00 87.83  ? 323 LEU C CD2 1 
ATOM   5898 N N   . LYS C 1 324 ? 97.446  137.471 146.223 1.00 84.23  ? 324 LYS C N   1 
ATOM   5899 C CA  . LYS C 1 324 ? 97.154  137.390 147.646 1.00 84.23  ? 324 LYS C CA  1 
ATOM   5900 C C   . LYS C 1 324 ? 98.385  136.974 148.432 1.00 84.23  ? 324 LYS C C   1 
ATOM   5901 O O   . LYS C 1 324 ? 98.537  137.376 149.587 1.00 84.23  ? 324 LYS C O   1 
ATOM   5902 C CB  . LYS C 1 324 ? 95.998  136.433 147.926 1.00 84.23  ? 324 LYS C CB  1 
ATOM   5903 C CG  . LYS C 1 324 ? 96.377  134.975 147.924 1.00 84.23  ? 324 LYS C CG  1 
ATOM   5904 C CD  . LYS C 1 324 ? 95.208  134.082 148.297 1.00 84.23  ? 324 LYS C CD  1 
ATOM   5905 C CE  . LYS C 1 324 ? 94.907  134.160 149.777 1.00 84.23  ? 324 LYS C CE  1 
ATOM   5906 N NZ  . LYS C 1 324 ? 93.883  133.164 150.181 1.00 84.23  ? 324 LYS C NZ  1 
ATOM   5907 N N   . ILE C 1 325 ? 99.296  136.217 147.819 1.00 83.99  ? 325 ILE C N   1 
ATOM   5908 C CA  . ILE C 1 325 ? 100.553 135.904 148.488 1.00 83.99  ? 325 ILE C CA  1 
ATOM   5909 C C   . ILE C 1 325 ? 101.385 137.163 148.669 1.00 83.99  ? 325 ILE C C   1 
ATOM   5910 O O   . ILE C 1 325 ? 102.036 137.340 149.698 1.00 83.99  ? 325 ILE C O   1 
ATOM   5911 C CB  . ILE C 1 325 ? 101.327 134.824 147.717 1.00 83.99  ? 325 ILE C CB  1 
ATOM   5912 C CG1 . ILE C 1 325 ? 100.764 133.444 148.023 1.00 83.99  ? 325 ILE C CG1 1 
ATOM   5913 C CG2 . ILE C 1 325 ? 102.784 134.844 148.102 1.00 83.99  ? 325 ILE C CG2 1 
ATOM   5914 C CD1 . ILE C 1 325 ? 101.485 132.349 147.304 1.00 83.99  ? 325 ILE C CD1 1 
ATOM   5915 N N   . LEU C 1 326 ? 101.391 138.053 147.677 1.00 84.82  ? 326 LEU C N   1 
ATOM   5916 C CA  . LEU C 1 326 ? 102.113 139.314 147.831 1.00 84.82  ? 326 LEU C CA  1 
ATOM   5917 C C   . LEU C 1 326 ? 101.492 140.183 148.917 1.00 84.82  ? 326 LEU C C   1 
ATOM   5918 O O   . LEU C 1 326 ? 102.202 140.764 149.755 1.00 84.82  ? 326 LEU C O   1 
ATOM   5919 C CB  . LEU C 1 326 ? 102.145 140.065 146.509 1.00 84.82  ? 326 LEU C CB  1 
ATOM   5920 C CG  . LEU C 1 326 ? 103.109 139.467 145.501 1.00 84.82  ? 326 LEU C CG  1 
ATOM   5921 C CD1 . LEU C 1 326 ? 103.096 140.272 144.223 1.00 84.82  ? 326 LEU C CD1 1 
ATOM   5922 C CD2 . LEU C 1 326 ? 104.485 139.432 146.103 1.00 84.82  ? 326 LEU C CD2 1 
ATOM   5923 N N   . TRP C 1 327 ? 100.167 140.300 148.914 1.00 87.88  ? 327 TRP C N   1 
ATOM   5924 C CA  . TRP C 1 327 ? 99.517  141.021 149.999 1.00 87.88  ? 327 TRP C CA  1 
ATOM   5925 C C   . TRP C 1 327 ? 99.891  140.410 151.340 1.00 87.88  ? 327 TRP C C   1 
ATOM   5926 O O   . TRP C 1 327 ? 100.096 141.123 152.334 1.00 87.88  ? 327 TRP C O   1 
ATOM   5927 C CB  . TRP C 1 327 ? 98.005  141.014 149.821 1.00 87.88  ? 327 TRP C CB  1 
ATOM   5928 C CG  . TRP C 1 327 ? 97.344  141.863 150.824 1.00 87.88  ? 327 TRP C CG  1 
ATOM   5929 C CD1 . TRP C 1 327 ? 96.430  141.476 151.752 1.00 87.88  ? 327 TRP C CD1 1 
ATOM   5930 C CD2 . TRP C 1 327 ? 97.539  143.265 151.008 1.00 87.88  ? 327 TRP C CD2 1 
ATOM   5931 N NE1 . TRP C 1 327 ? 96.046  142.550 152.513 1.00 87.88  ? 327 TRP C NE1 1 
ATOM   5932 C CE2 . TRP C 1 327 ? 96.713  143.662 152.072 1.00 87.88  ? 327 TRP C CE2 1 
ATOM   5933 C CE3 . TRP C 1 327 ? 98.331  144.224 150.374 1.00 87.88  ? 327 TRP C CE3 1 
ATOM   5934 C CZ2 . TRP C 1 327 ? 96.657  144.974 152.519 1.00 87.88  ? 327 TRP C CZ2 1 
ATOM   5935 C CZ3 . TRP C 1 327 ? 98.277  145.522 150.817 1.00 87.88  ? 327 TRP C CZ3 1 
ATOM   5936 C CH2 . TRP C 1 327 ? 97.447  145.888 151.880 1.00 87.88  ? 327 TRP C CH2 1 
ATOM   5937 N N   . SER C 1 328 ? 99.997  139.082 151.376 1.00 86.02  ? 328 SER C N   1 
ATOM   5938 C CA  . SER C 1 328 ? 100.425 138.401 152.583 1.00 86.02  ? 328 SER C CA  1 
ATOM   5939 C C   . SER C 1 328 ? 101.844 138.783 152.948 1.00 86.02  ? 328 SER C C   1 
ATOM   5940 O O   . SER C 1 328 ? 102.137 139.021 154.118 1.00 86.02  ? 328 SER C O   1 
ATOM   5941 C CB  . SER C 1 328 ? 100.322 136.896 152.398 1.00 86.02  ? 328 SER C CB  1 
ATOM   5942 O OG  . SER C 1 328 ? 101.413 136.432 151.632 1.00 86.02  ? 328 SER C OG  1 
ATOM   5943 N N   . VAL C 1 329 ? 102.744 138.856 151.965 1.00 84.10  ? 329 VAL C N   1 
ATOM   5944 C CA  . VAL C 1 329 ? 104.138 139.087 152.321 1.00 84.10  ? 329 VAL C CA  1 
ATOM   5945 C C   . VAL C 1 329 ? 104.144 140.418 153.039 1.00 84.10  ? 329 VAL C C   1 
ATOM   5946 O O   . VAL C 1 329 ? 104.647 140.492 154.154 1.00 84.10  ? 329 VAL C O   1 
ATOM   5947 C CB  . VAL C 1 329 ? 105.151 139.062 151.156 1.00 84.10  ? 329 VAL C CB  1 
ATOM   5948 C CG1 . VAL C 1 329 ? 105.075 137.756 150.380 1.00 84.10  ? 329 VAL C CG1 1 
ATOM   5949 C CG2 . VAL C 1 329 ? 105.089 140.278 150.277 1.00 84.10  ? 329 VAL C CG2 1 
ATOM   5950 N N   . LEU C 1 330 ? 103.440 141.421 152.516 1.00 85.90  ? 330 LEU C N   1 
ATOM   5951 C CA  . LEU C 1 330 ? 103.399 142.692 153.242 1.00 85.90  ? 330 LEU C CA  1 
ATOM   5952 C C   . LEU C 1 330 ? 102.838 142.509 154.651 1.00 85.90  ? 330 LEU C C   1 
ATOM   5953 O O   . LEU C 1 330 ? 103.573 142.559 155.658 1.00 85.90  ? 330 LEU C O   1 
ATOM   5954 C CB  . LEU C 1 330 ? 102.552 143.718 152.490 1.00 85.90  ? 330 LEU C CB  1 
ATOM   5955 C CG  . LEU C 1 330 ? 103.153 144.535 151.347 1.00 85.90  ? 330 LEU C CG  1 
ATOM   5956 C CD1 . LEU C 1 330 ? 104.284 145.414 151.849 1.00 85.90  ? 330 LEU C CD1 1 
ATOM   5957 C CD2 . LEU C 1 330 ? 103.600 143.666 150.212 1.00 85.90  ? 330 LEU C CD2 1 
ATOM   5958 N N   . THR C 1 331 ? 101.544 142.196 154.734 1.00 89.03  ? 331 THR C N   1 
ATOM   5959 C CA  . THR C 1 331 ? 100.831 142.385 155.992 1.00 89.03  ? 331 THR C CA  1 
ATOM   5960 C C   . THR C 1 331 ? 101.225 141.343 157.034 1.00 89.03  ? 331 THR C C   1 
ATOM   5961 O O   . THR C 1 331 ? 101.312 141.657 158.226 1.00 89.03  ? 331 THR C O   1 
ATOM   5962 C CB  . THR C 1 331 ? 99.320  142.382 155.746 1.00 89.03  ? 331 THR C CB  1 
ATOM   5963 O OG1 . THR C 1 331 ? 98.635  142.733 156.954 1.00 89.03  ? 331 THR C OG1 1 
ATOM   5964 C CG2 . THR C 1 331 ? 98.831  141.025 155.266 1.00 89.03  ? 331 THR C CG2 1 
ATOM   5965 N N   . GLN C 1 332 ? 101.464 140.104 156.616 1.00 87.52  ? 332 GLN C N   1 
ATOM   5966 C CA  . GLN C 1 332 ? 101.832 139.026 157.515 1.00 87.52  ? 332 GLN C CA  1 
ATOM   5967 C C   . GLN C 1 332 ? 103.308 138.682 157.419 1.00 87.52  ? 332 GLN C C   1 
ATOM   5968 O O   . GLN C 1 332 ? 103.721 137.629 157.904 1.00 87.52  ? 332 GLN C O   1 
ATOM   5969 C CB  . GLN C 1 332 ? 100.983 137.793 157.219 1.00 87.52  ? 332 GLN C CB  1 
ATOM   5970 C CG  . GLN C 1 332 ? 99.665  137.786 157.947 1.00 87.52  ? 332 GLN C CG  1 
ATOM   5971 C CD  . GLN C 1 332 ? 98.653  136.892 157.282 1.00 87.52  ? 332 GLN C CD  1 
ATOM   5972 O OE1 . GLN C 1 332 ? 98.270  135.854 157.821 1.00 87.52  ? 332 GLN C OE1 1 
ATOM   5973 N NE2 . GLN C 1 332 ? 98.218  137.283 156.093 1.00 87.52  ? 332 GLN C NE2 1 
ATOM   5974 N N   . PHE C 1 333 ? 104.110 139.535 156.795 1.00 79.19  ? 333 PHE C N   1 
ATOM   5975 C CA  . PHE C 1 333 ? 105.544 139.477 156.979 1.00 79.19  ? 333 PHE C CA  1 
ATOM   5976 C C   . PHE C 1 333 ? 105.921 140.412 158.101 1.00 79.19  ? 333 PHE C C   1 
ATOM   5977 O O   . PHE C 1 333 ? 106.745 140.076 158.954 1.00 79.19  ? 333 PHE C O   1 
ATOM   5978 C CB  . PHE C 1 333 ? 106.231 139.901 155.687 1.00 79.19  ? 333 PHE C CB  1 
ATOM   5979 C CG  . PHE C 1 333 ? 107.529 139.229 155.408 1.00 79.19  ? 333 PHE C CG  1 
ATOM   5980 C CD1 . PHE C 1 333 ? 107.565 137.941 154.928 1.00 79.19  ? 333 PHE C CD1 1 
ATOM   5981 C CD2 . PHE C 1 333 ? 108.711 139.918 155.541 1.00 79.19  ? 333 PHE C CD2 1 
ATOM   5982 C CE1 . PHE C 1 333 ? 108.758 137.338 154.630 1.00 79.19  ? 333 PHE C CE1 1 
ATOM   5983 C CE2 . PHE C 1 333 ? 109.900 139.321 155.246 1.00 79.19  ? 333 PHE C CE2 1 
ATOM   5984 C CZ  . PHE C 1 333 ? 109.925 138.027 154.790 1.00 79.19  ? 333 PHE C CZ  1 
ATOM   5985 N N   . ARG C 1 334 ? 105.296 141.586 158.129 1.00 84.33  ? 334 ARG C N   1 
ATOM   5986 C CA  . ARG C 1 334 ? 105.646 142.508 159.197 1.00 84.33  ? 334 ARG C CA  1 
ATOM   5987 C C   . ARG C 1 334 ? 105.153 142.027 160.558 1.00 84.33  ? 334 ARG C C   1 
ATOM   5988 O O   . ARG C 1 334 ? 105.808 142.282 161.570 1.00 84.33  ? 334 ARG C O   1 
ATOM   5989 C CB  . ARG C 1 334 ? 105.114 143.906 158.892 1.00 84.33  ? 334 ARG C CB  1 
ATOM   5990 C CG  . ARG C 1 334 ? 105.942 144.620 157.848 1.00 84.33  ? 334 ARG C CG  1 
ATOM   5991 C CD  . ARG C 1 334 ? 105.095 145.498 156.958 1.00 84.33  ? 334 ARG C CD  1 
ATOM   5992 N NE  . ARG C 1 334 ? 104.649 146.711 157.635 1.00 84.33  ? 334 ARG C NE  1 
ATOM   5993 C CZ  . ARG C 1 334 ? 105.445 147.726 157.962 1.00 84.33  ? 334 ARG C CZ  1 
ATOM   5994 N NH1 . ARG C 1 334 ? 104.947 148.792 158.573 1.00 84.33  ? 334 ARG C NH1 1 
ATOM   5995 N NH2 . ARG C 1 334 ? 106.739 147.686 157.667 1.00 84.33  ? 334 ARG C NH2 1 
ATOM   5996 N N   . THR C 1 335 ? 104.012 141.337 160.615 1.00 90.08  ? 335 THR C N   1 
ATOM   5997 C CA  . THR C 1 335 ? 103.415 141.033 161.915 1.00 90.08  ? 335 THR C CA  1 
ATOM   5998 C C   . THR C 1 335 ? 102.896 139.609 162.067 1.00 90.08  ? 335 THR C C   1 
ATOM   5999 O O   . THR C 1 335 ? 101.792 139.418 162.583 1.00 90.08  ? 335 THR C O   1 
ATOM   6000 C CB  . THR C 1 335 ? 102.245 141.978 162.213 1.00 90.08  ? 335 THR C CB  1 
ATOM   6001 O OG1 . THR C 1 335 ? 101.093 141.554 161.476 1.00 90.08  ? 335 THR C OG1 1 
ATOM   6002 C CG2 . THR C 1 335 ? 102.569 143.418 161.858 1.00 90.08  ? 335 THR C CG2 1 
ATOM   6003 N N   . GLU C 1 336 ? 103.645 138.599 161.638 1.00 89.22  ? 336 GLU C N   1 
ATOM   6004 C CA  . GLU C 1 336 ? 103.145 137.248 161.857 1.00 89.22  ? 336 GLU C CA  1 
ATOM   6005 C C   . GLU C 1 336 ? 104.266 136.346 162.371 1.00 89.22  ? 336 GLU C C   1 
ATOM   6006 O O   . GLU C 1 336 ? 104.488 135.248 161.857 1.00 89.22  ? 336 GLU C O   1 
ATOM   6007 C CB  . GLU C 1 336 ? 102.506 136.709 160.575 1.00 89.22  ? 336 GLU C CB  1 
ATOM   6008 C CG  . GLU C 1 336 ? 101.891 135.325 160.688 1.00 89.22  ? 336 GLU C CG  1 
ATOM   6009 C CD  . GLU C 1 336 ? 100.710 135.304 161.636 1.00 89.22  ? 336 GLU C CD  1 
ATOM   6010 O OE1 . GLU C 1 336 ? 100.073 136.363 161.810 1.00 89.22  ? 336 GLU C OE1 1 
ATOM   6011 O OE2 . GLU C 1 336 ? 100.438 134.239 162.229 1.00 89.22  ? 336 GLU C OE2 1 
ATOM   6012 N N   . GLY C 1 337 ? 105.001 136.812 163.367 1.00 87.05  ? 337 GLY C N   1 
ATOM   6013 C CA  . GLY C 1 337 ? 106.059 136.028 163.956 1.00 87.05  ? 337 GLY C CA  1 
ATOM   6014 C C   . GLY C 1 337 ? 107.263 136.883 164.240 1.00 87.05  ? 337 GLY C C   1 
ATOM   6015 O O   . GLY C 1 337 ? 107.170 138.104 164.396 1.00 87.05  ? 337 GLY C O   1 
ATOM   6016 N N   . ASN C 1 338 ? 108.421 136.235 164.313 1.00 77.12  ? 338 ASN C N   1 
ATOM   6017 C CA  . ASN C 1 338 ? 109.655 136.955 164.578 1.00 77.12  ? 338 ASN C CA  1 
ATOM   6018 C C   . ASN C 1 338 ? 109.944 137.927 163.443 1.00 77.12  ? 338 ASN C C   1 
ATOM   6019 O O   . ASN C 1 338 ? 109.922 137.558 162.268 1.00 77.12  ? 338 ASN C O   1 
ATOM   6020 C CB  . ASN C 1 338 ? 110.808 135.968 164.740 1.00 77.12  ? 338 ASN C CB  1 
ATOM   6021 C CG  . ASN C 1 338 ? 111.843 136.442 165.726 1.00 77.12  ? 338 ASN C CG  1 
ATOM   6022 O OD1 . ASN C 1 338 ? 111.637 137.424 166.436 1.00 77.12  ? 338 ASN C OD1 1 
ATOM   6023 N ND2 . ASN C 1 338 ? 112.971 135.747 165.776 1.00 77.12  ? 338 ASN C ND2 1 
ATOM   6024 N N   . TYR C 1 339 ? 110.211 139.184 163.797 1.00 73.32  ? 339 TYR C N   1 
ATOM   6025 C CA  . TYR C 1 339 ? 110.476 140.193 162.779 1.00 73.32  ? 339 TYR C CA  1 
ATOM   6026 C C   . TYR C 1 339 ? 111.627 141.110 163.182 1.00 73.32  ? 339 TYR C C   1 
ATOM   6027 O O   . TYR C 1 339 ? 111.723 142.239 162.691 1.00 73.32  ? 339 TYR C O   1 
ATOM   6028 C CB  . TYR C 1 339 ? 109.208 141.002 162.490 1.00 73.32  ? 339 TYR C CB  1 
ATOM   6029 C CG  . TYR C 1 339 ? 109.317 141.908 161.290 1.00 73.32  ? 339 TYR C CG  1 
ATOM   6030 C CD1 . TYR C 1 339 ? 109.644 141.401 160.048 1.00 73.32  ? 339 TYR C CD1 1 
ATOM   6031 C CD2 . TYR C 1 339 ? 109.091 143.270 161.403 1.00 73.32  ? 339 TYR C CD2 1 
ATOM   6032 C CE1 . TYR C 1 339 ? 109.747 142.220 158.957 1.00 73.32  ? 339 TYR C CE1 1 
ATOM   6033 C CE2 . TYR C 1 339 ? 109.193 144.095 160.314 1.00 73.32  ? 339 TYR C CE2 1 
ATOM   6034 C CZ  . TYR C 1 339 ? 109.521 143.563 159.096 1.00 73.32  ? 339 TYR C CZ  1 
ATOM   6035 O OH  . TYR C 1 339 ? 109.622 144.381 158.003 1.00 73.32  ? 339 TYR C OH  1 
ATOM   6036 N N   . VAL C 1 340 ? 112.505 140.649 164.066 1.00 65.12  ? 340 VAL C N   1 
ATOM   6037 C CA  . VAL C 1 340 ? 113.724 141.363 164.410 1.00 65.12  ? 340 VAL C CA  1 
ATOM   6038 C C   . VAL C 1 340 ? 114.892 140.557 163.872 1.00 65.12  ? 340 VAL C C   1 
ATOM   6039 O O   . VAL C 1 340 ? 115.074 139.394 164.244 1.00 65.12  ? 340 VAL C O   1 
ATOM   6040 C CB  . VAL C 1 340 ? 113.842 141.604 165.923 1.00 65.12  ? 340 VAL C CB  1 
ATOM   6041 C CG1 . VAL C 1 340 ? 112.726 142.492 166.382 1.00 65.12  ? 340 VAL C CG1 1 
ATOM   6042 C CG2 . VAL C 1 340 ? 113.746 140.309 166.683 1.00 65.12  ? 340 VAL C CG2 1 
ATOM   6043 N N   . LEU C 1 341 ? 115.666 141.158 162.977 1.00 59.72  ? 341 LEU C N   1 
ATOM   6044 C CA  . LEU C 1 341 ? 116.780 140.447 162.373 1.00 59.72  ? 341 LEU C CA  1 
ATOM   6045 C C   . LEU C 1 341 ? 117.773 140.012 163.437 1.00 59.72  ? 341 LEU C C   1 
ATOM   6046 O O   . LEU C 1 341 ? 118.137 140.783 164.325 1.00 59.72  ? 341 LEU C O   1 
ATOM   6047 C CB  . LEU C 1 341 ? 117.457 141.317 161.321 1.00 59.72  ? 341 LEU C CB  1 
ATOM   6048 C CG  . LEU C 1 341 ? 118.636 140.711 160.566 1.00 59.72  ? 341 LEU C CG  1 
ATOM   6049 C CD1 . LEU C 1 341 ? 118.649 141.147 159.149 1.00 59.72  ? 341 LEU C CD1 1 
ATOM   6050 C CD2 . LEU C 1 341 ? 119.883 141.221 161.188 1.00 59.72  ? 341 LEU C CD2 1 
ATOM   6051 N N   . ASN C 1 342 ? 118.200 138.757 163.349 1.00 58.52  ? 342 ASN C N   1 
ATOM   6052 C CA  . ASN C 1 342 ? 119.138 138.168 164.297 1.00 58.52  ? 342 ASN C CA  1 
ATOM   6053 C C   . ASN C 1 342 ? 120.060 137.249 163.519 1.00 58.52  ? 342 ASN C C   1 
ATOM   6054 O O   . ASN C 1 342 ? 119.696 136.111 163.231 1.00 58.52  ? 342 ASN C O   1 
ATOM   6055 C CB  . ASN C 1 342 ? 118.410 137.397 165.388 1.00 58.52  ? 342 ASN C CB  1 
ATOM   6056 C CG  . ASN C 1 342 ? 119.335 136.904 166.464 1.00 58.52  ? 342 ASN C CG  1 
ATOM   6057 O OD1 . ASN C 1 342 ? 120.534 137.130 166.414 1.00 58.52  ? 342 ASN C OD1 1 
ATOM   6058 N ND2 . ASN C 1 342 ? 118.783 136.211 167.442 1.00 58.52  ? 342 ASN C ND2 1 
ATOM   6059 N N   . PHE C 1 343 ? 121.246 137.731 163.183 1.00 57.75  ? 343 PHE C N   1 
ATOM   6060 C CA  . PHE C 1 343 ? 122.178 136.929 162.411 1.00 57.75  ? 343 PHE C CA  1 
ATOM   6061 C C   . PHE C 1 343 ? 122.676 135.711 163.163 1.00 57.75  ? 343 PHE C C   1 
ATOM   6062 O O   . PHE C 1 343 ? 123.154 134.772 162.528 1.00 57.75  ? 343 PHE C O   1 
ATOM   6063 C CB  . PHE C 1 343 ? 123.369 137.778 161.990 1.00 57.75  ? 343 PHE C CB  1 
ATOM   6064 C CG  . PHE C 1 343 ? 123.139 138.558 160.745 1.00 57.75  ? 343 PHE C CG  1 
ATOM   6065 C CD1 . PHE C 1 343 ? 123.212 139.926 160.754 1.00 57.75  ? 343 PHE C CD1 1 
ATOM   6066 C CD2 . PHE C 1 343 ? 122.849 137.922 159.568 1.00 57.75  ? 343 PHE C CD2 1 
ATOM   6067 C CE1 . PHE C 1 343 ? 123.001 140.637 159.614 1.00 57.75  ? 343 PHE C CE1 1 
ATOM   6068 C CE2 . PHE C 1 343 ? 122.640 138.635 158.431 1.00 57.75  ? 343 PHE C CE2 1 
ATOM   6069 C CZ  . PHE C 1 343 ? 122.715 139.992 158.454 1.00 57.75  ? 343 PHE C CZ  1 
ATOM   6070 N N   . ALA C 1 344 ? 122.582 135.699 164.486 1.00 58.32  ? 344 ALA C N   1 
ATOM   6071 C CA  . ALA C 1 344 ? 123.075 134.580 165.269 1.00 58.32  ? 344 ALA C CA  1 
ATOM   6072 C C   . ALA C 1 344 ? 122.195 133.350 165.178 1.00 58.32  ? 344 ALA C C   1 
ATOM   6073 O O   . ALA C 1 344 ? 122.716 132.234 165.215 1.00 58.32  ? 344 ALA C O   1 
ATOM   6074 C CB  . ALA C 1 344 ? 123.209 134.978 166.735 1.00 58.32  ? 344 ALA C CB  1 
ATOM   6075 N N   . THR C 1 345 ? 120.881 133.519 165.077 1.00 61.77  ? 345 THR C N   1 
ATOM   6076 C CA  . THR C 1 345 ? 119.954 132.402 164.980 1.00 61.77  ? 345 THR C CA  1 
ATOM   6077 C C   . THR C 1 345 ? 119.416 132.252 163.566 1.00 61.77  ? 345 THR C C   1 
ATOM   6078 O O   . THR C 1 345 ? 118.432 131.549 163.346 1.00 61.77  ? 345 THR C O   1 
ATOM   6079 C CB  . THR C 1 345 ? 118.802 132.558 165.965 1.00 61.77  ? 345 THR C CB  1 
ATOM   6080 O OG1 . THR C 1 345 ? 118.071 133.745 165.653 1.00 61.77  ? 345 THR C OG1 1 
ATOM   6081 C CG2 . THR C 1 345 ? 119.329 132.667 167.367 1.00 61.77  ? 345 THR C CG2 1 
ATOM   6082 N N   . GLN C 1 346 ? 120.056 132.907 162.609 1.00 64.65  ? 346 GLN C N   1 
ATOM   6083 C CA  . GLN C 1 346 ? 119.675 132.853 161.204 1.00 64.65  ? 346 GLN C CA  1 
ATOM   6084 C C   . GLN C 1 346 ? 118.191 133.126 161.030 1.00 64.65  ? 346 GLN C C   1 
ATOM   6085 O O   . GLN C 1 346 ? 117.461 132.380 160.383 1.00 64.65  ? 346 GLN C O   1 
ATOM   6086 C CB  . GLN C 1 346 ? 120.058 131.521 160.580 1.00 64.65  ? 346 GLN C CB  1 
ATOM   6087 C CG  . GLN C 1 346 ? 121.535 131.294 160.477 1.00 64.65  ? 346 GLN C CG  1 
ATOM   6088 C CD  . GLN C 1 346 ? 121.861 129.954 159.870 1.00 64.65  ? 346 GLN C CD  1 
ATOM   6089 O OE1 . GLN C 1 346 ? 120.973 129.162 159.584 1.00 64.65  ? 346 GLN C OE1 1 
ATOM   6090 N NE2 . GLN C 1 346 ? 123.141 129.698 159.656 1.00 64.65  ? 346 GLN C NE2 1 
ATOM   6091 N N   . GLN C 1 347 ? 117.749 134.209 161.632 1.00 64.49  ? 347 GLN C N   1 
ATOM   6092 C CA  . GLN C 1 347 ? 116.386 134.682 161.465 1.00 64.49  ? 347 GLN C CA  1 
ATOM   6093 C C   . GLN C 1 347 ? 116.487 135.865 160.516 1.00 64.49  ? 347 GLN C C   1 
ATOM   6094 O O   . GLN C 1 347 ? 116.812 136.977 160.932 1.00 64.49  ? 347 GLN C O   1 
ATOM   6095 C CB  . GLN C 1 347 ? 115.767 135.065 162.799 1.00 64.49  ? 347 GLN C CB  1 
ATOM   6096 C CG  . GLN C 1 347 ? 114.284 135.244 162.745 1.00 64.49  ? 347 GLN C CG  1 
ATOM   6097 C CD  . GLN C 1 347 ? 113.902 136.601 162.247 1.00 64.49  ? 347 GLN C CD  1 
ATOM   6098 O OE1 . GLN C 1 347 ? 114.646 137.552 162.404 1.00 64.49  ? 347 GLN C OE1 1 
ATOM   6099 N NE2 . GLN C 1 347 ? 112.732 136.704 161.646 1.00 64.49  ? 347 GLN C NE2 1 
ATOM   6100 N N   . TYR C 1 348 ? 116.242 135.616 159.233 1.00 65.78  ? 348 TYR C N   1 
ATOM   6101 C CA  . TYR C 1 348 ? 116.424 136.614 158.192 1.00 65.78  ? 348 TYR C CA  1 
ATOM   6102 C C   . TYR C 1 348 ? 115.161 137.387 157.872 1.00 65.78  ? 348 TYR C C   1 
ATOM   6103 O O   . TYR C 1 348 ? 115.223 138.350 157.109 1.00 65.78  ? 348 TYR C O   1 
ATOM   6104 C CB  . TYR C 1 348 ? 116.942 135.946 156.921 1.00 65.78  ? 348 TYR C CB  1 
ATOM   6105 C CG  . TYR C 1 348 ? 118.244 135.220 157.121 1.00 65.78  ? 348 TYR C CG  1 
ATOM   6106 C CD1 . TYR C 1 348 ? 119.363 135.886 157.577 1.00 65.78  ? 348 TYR C CD1 1 
ATOM   6107 C CD2 . TYR C 1 348 ? 118.347 133.866 156.872 1.00 65.78  ? 348 TYR C CD2 1 
ATOM   6108 C CE1 . TYR C 1 348 ? 120.544 135.232 157.764 1.00 65.78  ? 348 TYR C CE1 1 
ATOM   6109 C CE2 . TYR C 1 348 ? 119.523 133.207 157.057 1.00 65.78  ? 348 TYR C CE2 1 
ATOM   6110 C CZ  . TYR C 1 348 ? 120.619 133.893 157.504 1.00 65.78  ? 348 TYR C CZ  1 
ATOM   6111 O OH  . TYR C 1 348 ? 121.806 133.238 157.695 1.00 65.78  ? 348 TYR C OH  1 
ATOM   6112 N N   . LYS C 1 349 ? 114.021 137.000 158.424 1.00 67.15  ? 349 LYS C N   1 
ATOM   6113 C CA  . LYS C 1 349 ? 112.769 137.701 158.176 1.00 67.15  ? 349 LYS C CA  1 
ATOM   6114 C C   . LYS C 1 349 ? 112.836 139.032 158.906 1.00 67.15  ? 349 LYS C C   1 
ATOM   6115 O O   . LYS C 1 349 ? 112.698 139.083 160.129 1.00 67.15  ? 349 LYS C O   1 
ATOM   6116 C CB  . LYS C 1 349 ? 111.588 136.858 158.644 1.00 67.15  ? 349 LYS C CB  1 
ATOM   6117 C CG  . LYS C 1 349 ? 110.236 137.394 158.266 1.00 67.15  ? 349 LYS C CG  1 
ATOM   6118 C CD  . LYS C 1 349 ? 109.212 136.285 158.255 1.00 67.15  ? 349 LYS C CD  1 
ATOM   6119 C CE  . LYS C 1 349 ? 108.712 135.974 159.634 1.00 67.15  ? 349 LYS C CE  1 
ATOM   6120 N NZ  . LYS C 1 349 ? 107.758 137.004 160.081 1.00 67.15  ? 349 LYS C NZ  1 
ATOM   6121 N N   . CYS C 1 350 ? 113.049 140.103 158.160 1.00 74.24  ? 350 CYS C N   1 
ATOM   6122 C CA  . CYS C 1 350 ? 113.316 141.422 158.719 1.00 74.24  ? 350 CYS C CA  1 
ATOM   6123 C C   . CYS C 1 350 ? 112.779 142.457 157.741 1.00 74.24  ? 350 CYS C C   1 
ATOM   6124 O O   . CYS C 1 350 ? 112.156 142.111 156.731 1.00 74.24  ? 350 CYS C O   1 
ATOM   6125 C CB  . CYS C 1 350 ? 114.807 141.624 158.954 1.00 74.24  ? 350 CYS C CB  1 
ATOM   6126 S SG  . CYS C 1 350 ? 115.731 141.566 157.418 1.00 74.24  ? 350 CYS C SG  1 
ATOM   6127 N N   . TRP C 1 351 ? 113.026 143.735 158.031 1.00 79.46  ? 351 TRP C N   1 
ATOM   6128 C CA  . TRP C 1 351 ? 112.627 144.777 157.096 1.00 79.46  ? 351 TRP C CA  1 
ATOM   6129 C C   . TRP C 1 351 ? 113.608 144.929 155.949 1.00 79.46  ? 351 TRP C C   1 
ATOM   6130 O O   . TRP C 1 351 ? 113.306 145.633 154.983 1.00 79.46  ? 351 TRP C O   1 
ATOM   6131 C CB  . TRP C 1 351 ? 112.458 146.113 157.817 1.00 79.46  ? 351 TRP C CB  1 
ATOM   6132 C CG  . TRP C 1 351 ? 113.724 146.716 158.340 1.00 79.46  ? 351 TRP C CG  1 
ATOM   6133 C CD1 . TRP C 1 351 ? 114.195 146.636 159.614 1.00 79.46  ? 351 TRP C CD1 1 
ATOM   6134 C CD2 . TRP C 1 351 ? 114.668 147.511 157.615 1.00 79.46  ? 351 TRP C CD2 1 
ATOM   6135 N NE1 . TRP C 1 351 ? 115.376 147.322 159.727 1.00 79.46  ? 351 TRP C NE1 1 
ATOM   6136 C CE2 . TRP C 1 351 ? 115.686 147.871 158.513 1.00 79.46  ? 351 TRP C CE2 1 
ATOM   6137 C CE3 . TRP C 1 351 ? 114.753 147.950 156.294 1.00 79.46  ? 351 TRP C CE3 1 
ATOM   6138 C CZ2 . TRP C 1 351 ? 116.774 148.640 158.132 1.00 79.46  ? 351 TRP C CZ2 1 
ATOM   6139 C CZ3 . TRP C 1 351 ? 115.833 148.716 155.919 1.00 79.46  ? 351 TRP C CZ3 1 
ATOM   6140 C CH2 . TRP C 1 351 ? 116.830 149.055 156.834 1.00 79.46  ? 351 TRP C CH2 1 
ATOM   6141 N N   . ILE C 1 352 ? 114.779 144.301 156.028 1.00 78.67  ? 352 ILE C N   1 
ATOM   6142 C CA  . ILE C 1 352 ? 115.729 144.318 154.927 1.00 78.67  ? 352 ILE C CA  1 
ATOM   6143 C C   . ILE C 1 352 ? 115.454 143.189 153.943 1.00 78.67  ? 352 ILE C C   1 
ATOM   6144 O O   . ILE C 1 352 ? 115.838 143.275 152.775 1.00 78.67  ? 352 ILE C O   1 
ATOM   6145 C CB  . ILE C 1 352 ? 117.181 144.260 155.435 1.00 78.67  ? 352 ILE C CB  1 
ATOM   6146 C CG1 . ILE C 1 352 ? 117.470 145.397 156.415 1.00 78.67  ? 352 ILE C CG1 1 
ATOM   6147 C CG2 . ILE C 1 352 ? 118.163 144.389 154.290 1.00 78.67  ? 352 ILE C CG2 1 
ATOM   6148 C CD1 . ILE C 1 352 ? 117.290 145.015 157.870 1.00 78.67  ? 352 ILE C CD1 1 
ATOM   6149 N N   . SER C 1 353 ? 114.770 142.137 154.385 1.00 76.85  ? 353 SER C N   1 
ATOM   6150 C CA  . SER C 1 353 ? 114.429 141.020 153.525 1.00 76.85  ? 353 SER C CA  1 
ATOM   6151 C C   . SER C 1 353 ? 113.061 141.149 152.879 1.00 76.85  ? 353 SER C C   1 
ATOM   6152 O O   . SER C 1 353 ? 112.807 140.476 151.875 1.00 76.85  ? 353 SER C O   1 
ATOM   6153 C CB  . SER C 1 353 ? 114.479 139.709 154.315 1.00 76.85  ? 353 SER C CB  1 
ATOM   6154 O OG  . SER C 1 353 ? 113.999 138.638 153.534 1.00 76.85  ? 353 SER C OG  1 
ATOM   6155 N N   . LEU C 1 354 ? 112.184 141.978 153.419 1.00 79.39  ? 354 LEU C N   1 
ATOM   6156 C CA  . LEU C 1 354 ? 110.865 142.229 152.855 1.00 79.39  ? 354 LEU C CA  1 
ATOM   6157 C C   . LEU C 1 354 ? 110.950 142.820 151.450 1.00 79.39  ? 354 LEU C C   1 
ATOM   6158 O O   . LEU C 1 354 ? 110.214 142.370 150.566 1.00 79.39  ? 354 LEU C O   1 
ATOM   6159 C CB  . LEU C 1 354 ? 110.066 143.137 153.790 1.00 79.39  ? 354 LEU C CB  1 
ATOM   6160 C CG  . LEU C 1 354 ? 108.666 143.578 153.390 1.00 79.39  ? 354 LEU C CG  1 
ATOM   6161 C CD1 . LEU C 1 354 ? 107.780 143.609 154.611 1.00 79.39  ? 354 LEU C CD1 1 
ATOM   6162 C CD2 . LEU C 1 354 ? 108.722 144.946 152.759 1.00 79.39  ? 354 LEU C CD2 1 
ATOM   6163 N N   . PRO C 1 355 ? 111.790 143.833 151.194 1.00 81.79  ? 355 PRO C N   1 
ATOM   6164 C CA  . PRO C 1 355 ? 111.927 144.299 149.805 1.00 81.79  ? 355 PRO C CA  1 
ATOM   6165 C C   . PRO C 1 355 ? 112.405 143.221 148.857 1.00 81.79  ? 355 PRO C C   1 
ATOM   6166 O O   . PRO C 1 355 ? 111.890 143.110 147.742 1.00 81.79  ? 355 PRO C O   1 
ATOM   6167 C CB  . PRO C 1 355 ? 112.941 145.439 149.922 1.00 81.79  ? 355 PRO C CB  1 
ATOM   6168 C CG  . PRO C 1 355 ? 112.808 145.911 151.290 1.00 81.79  ? 355 PRO C CG  1 
ATOM   6169 C CD  . PRO C 1 355 ? 112.551 144.697 152.109 1.00 81.79  ? 355 PRO C CD  1 
ATOM   6170 N N   . ILE C 1 356 ? 113.382 142.416 149.273 1.00 84.40  ? 356 ILE C N   1 
ATOM   6171 C CA  . ILE C 1 356 ? 113.892 141.375 148.391 1.00 84.40  ? 356 ILE C CA  1 
ATOM   6172 C C   . ILE C 1 356 ? 112.797 140.372 148.078 1.00 84.40  ? 356 ILE C C   1 
ATOM   6173 O O   . ILE C 1 356 ? 112.599 139.991 146.920 1.00 84.40  ? 356 ILE C O   1 
ATOM   6174 C CB  . ILE C 1 356 ? 115.118 140.692 149.016 1.00 84.40  ? 356 ILE C CB  1 
ATOM   6175 C CG1 . ILE C 1 356 ? 116.238 141.705 149.221 1.00 84.40  ? 356 ILE C CG1 1 
ATOM   6176 C CG2 . ILE C 1 356 ? 115.593 139.564 148.136 1.00 84.40  ? 356 ILE C CG2 1 
ATOM   6177 C CD1 . ILE C 1 356 ? 117.369 141.182 150.058 1.00 84.40  ? 356 ILE C CD1 1 
ATOM   6178 N N   . VAL C 1 357 ? 112.054 139.946 149.097 1.00 82.12  ? 357 VAL C N   1 
ATOM   6179 C CA  . VAL C 1 357 ? 110.980 138.985 148.870 1.00 82.12  ? 357 VAL C CA  1 
ATOM   6180 C C   . VAL C 1 357 ? 109.924 139.570 147.945 1.00 82.12  ? 357 VAL C C   1 
ATOM   6181 O O   . VAL C 1 357 ? 109.517 138.935 146.964 1.00 82.12  ? 357 VAL C O   1 
ATOM   6182 C CB  . VAL C 1 357 ? 110.370 138.551 150.210 1.00 82.12  ? 357 VAL C CB  1 
ATOM   6183 C CG1 . VAL C 1 357 ? 109.051 137.867 149.981 1.00 82.12  ? 357 VAL C CG1 1 
ATOM   6184 C CG2 . VAL C 1 357 ? 111.321 137.636 150.931 1.00 82.12  ? 357 VAL C CG2 1 
ATOM   6185 N N   . PHE C 1 358 ? 109.472 140.789 148.232 1.00 83.58  ? 358 PHE C N   1 
ATOM   6186 C CA  . PHE C 1 358 ? 108.403 141.378 147.439 1.00 83.58  ? 358 PHE C CA  1 
ATOM   6187 C C   . PHE C 1 358 ? 108.834 141.578 145.996 1.00 83.58  ? 358 PHE C C   1 
ATOM   6188 O O   . PHE C 1 358 ? 108.080 141.259 145.077 1.00 83.58  ? 358 PHE C O   1 
ATOM   6189 C CB  . PHE C 1 358 ? 107.961 142.699 148.064 1.00 83.58  ? 358 PHE C CB  1 
ATOM   6190 C CG  . PHE C 1 358 ? 106.918 143.426 147.275 1.00 83.58  ? 358 PHE C CG  1 
ATOM   6191 C CD1 . PHE C 1 358 ? 105.583 143.247 147.553 1.00 83.58  ? 358 PHE C CD1 1 
ATOM   6192 C CD2 . PHE C 1 358 ? 107.270 144.314 146.278 1.00 83.58  ? 358 PHE C CD2 1 
ATOM   6193 C CE1 . PHE C 1 358 ? 104.619 143.920 146.848 1.00 83.58  ? 358 PHE C CE1 1 
ATOM   6194 C CE2 . PHE C 1 358 ? 106.307 144.987 145.563 1.00 83.58  ? 358 PHE C CE2 1 
ATOM   6195 C CZ  . PHE C 1 358 ? 104.979 144.791 145.851 1.00 83.58  ? 358 PHE C CZ  1 
ATOM   6196 N N   . VAL C 1 359 ? 110.041 142.095 145.773 1.00 85.43  ? 359 VAL C N   1 
ATOM   6197 C CA  . VAL C 1 359 ? 110.515 142.318 144.412 1.00 85.43  ? 359 VAL C CA  1 
ATOM   6198 C C   . VAL C 1 359 ? 110.672 140.997 143.676 1.00 85.43  ? 359 VAL C C   1 
ATOM   6199 O O   . VAL C 1 359 ? 110.277 140.861 142.513 1.00 85.43  ? 359 VAL C O   1 
ATOM   6200 C CB  . VAL C 1 359 ? 111.834 143.107 144.432 1.00 85.43  ? 359 VAL C CB  1 
ATOM   6201 C CG1 . VAL C 1 359 ? 112.501 143.049 143.075 1.00 85.43  ? 359 VAL C CG1 1 
ATOM   6202 C CG2 . VAL C 1 359 ? 111.576 144.540 144.844 1.00 85.43  ? 359 VAL C CG2 1 
ATOM   6203 N N   . LEU C 1 360 ? 111.242 139.997 144.341 1.00 87.33  ? 360 LEU C N   1 
ATOM   6204 C CA  . LEU C 1 360 ? 111.574 138.765 143.647 1.00 87.33  ? 360 LEU C CA  1 
ATOM   6205 C C   . LEU C 1 360 ? 110.349 137.873 143.462 1.00 87.33  ? 360 LEU C C   1 
ATOM   6206 O O   . LEU C 1 360 ? 110.405 136.905 142.701 1.00 87.33  ? 360 LEU C O   1 
ATOM   6207 C CB  . LEU C 1 360 ? 112.716 138.085 144.403 1.00 87.33  ? 360 LEU C CB  1 
ATOM   6208 C CG  . LEU C 1 360 ? 113.462 136.856 143.909 1.00 87.33  ? 360 LEU C CG  1 
ATOM   6209 C CD1 . LEU C 1 360 ? 114.850 136.875 144.496 1.00 87.33  ? 360 LEU C CD1 1 
ATOM   6210 C CD2 . LEU C 1 360 ? 112.763 135.642 144.414 1.00 87.33  ? 360 LEU C CD2 1 
ATOM   6211 N N   . ILE C 1 361 ? 109.234 138.186 144.128 1.00 88.84  ? 361 ILE C N   1 
ATOM   6212 C CA  . ILE C 1 361 ? 107.973 137.540 143.759 1.00 88.84  ? 361 ILE C CA  1 
ATOM   6213 C C   . ILE C 1 361 ? 107.203 138.387 142.749 1.00 88.84  ? 361 ILE C C   1 
ATOM   6214 O O   . ILE C 1 361 ? 106.505 137.852 141.875 1.00 88.84  ? 361 ILE C O   1 
ATOM   6215 C CB  . ILE C 1 361 ? 107.112 137.244 144.998 1.00 88.84  ? 361 ILE C CB  1 
ATOM   6216 C CG1 . ILE C 1 361 ? 107.901 136.437 146.019 1.00 88.84  ? 361 ILE C CG1 1 
ATOM   6217 C CG2 . ILE C 1 361 ? 105.871 136.463 144.604 1.00 88.84  ? 361 ILE C CG2 1 
ATOM   6218 C CD1 . ILE C 1 361 ? 108.257 135.070 145.534 1.00 88.84  ? 361 ILE C CD1 1 
ATOM   6219 N N   . GLY C 1 362 ? 107.316 139.712 142.834 1.00 93.57  ? 362 GLY C N   1 
ATOM   6220 C CA  . GLY C 1 362 ? 106.735 140.559 141.812 1.00 93.57  ? 362 GLY C CA  1 
ATOM   6221 C C   . GLY C 1 362 ? 107.343 140.312 140.453 1.00 93.57  ? 362 GLY C C   1 
ATOM   6222 O O   . GLY C 1 362 ? 106.726 140.611 139.432 1.00 93.57  ? 362 GLY C O   1 
ATOM   6223 N N   . ALA C 1 363 ? 108.554 139.767 140.414 1.00 92.23  ? 363 ALA C N   1 
ATOM   6224 C CA  . ALA C 1 363 ? 109.126 139.347 139.142 1.00 92.23  ? 363 ALA C CA  1 
ATOM   6225 C C   . ALA C 1 363 ? 108.225 138.315 138.476 1.00 92.23  ? 363 ALA C C   1 
ATOM   6226 O O   . ALA C 1 363 ? 107.816 138.483 137.317 1.00 92.23  ? 363 ALA C O   1 
ATOM   6227 C CB  . ALA C 1 363 ? 110.527 138.778 139.351 1.00 92.23  ? 363 ALA C CB  1 
ATOM   6228 N N   . LEU C 1 364 ? 107.893 137.254 139.212 1.00 93.34  ? 364 LEU C N   1 
ATOM   6229 C CA  . LEU C 1 364 ? 106.980 136.251 138.684 1.00 93.34  ? 364 LEU C CA  1 
ATOM   6230 C C   . LEU C 1 364 ? 105.631 136.868 138.372 1.00 93.34  ? 364 LEU C C   1 
ATOM   6231 O O   . LEU C 1 364 ? 104.976 136.490 137.395 1.00 93.34  ? 364 LEU C O   1 
ATOM   6232 C CB  . LEU C 1 364 ? 106.813 135.096 139.673 1.00 93.34  ? 364 LEU C CB  1 
ATOM   6233 C CG  . LEU C 1 364 ? 107.840 133.961 139.715 1.00 93.34  ? 364 LEU C CG  1 
ATOM   6234 C CD1 . LEU C 1 364 ? 107.849 133.195 138.410 1.00 93.34  ? 364 LEU C CD1 1 
ATOM   6235 C CD2 . LEU C 1 364 ? 109.225 134.475 140.038 1.00 93.34  ? 364 LEU C CD2 1 
ATOM   6236 N N   . GLN C 1 365 ? 105.193 137.816 139.196 1.00 95.22  ? 365 GLN C N   1 
ATOM   6237 C CA  . GLN C 1 365 ? 103.889 138.426 138.956 1.00 95.22  ? 365 GLN C CA  1 
ATOM   6238 C C   . GLN C 1 365 ? 103.861 139.184 137.633 1.00 95.22  ? 365 GLN C C   1 
ATOM   6239 O O   . GLN C 1 365 ? 102.897 139.072 136.868 1.00 95.22  ? 365 GLN C O   1 
ATOM   6240 C CB  . GLN C 1 365 ? 103.518 139.351 140.104 1.00 95.22  ? 365 GLN C CB  1 
ATOM   6241 C CG  . GLN C 1 365 ? 102.152 139.954 139.936 1.00 95.22  ? 365 GLN C CG  1 
ATOM   6242 C CD  . GLN C 1 365 ? 101.153 138.942 139.435 1.00 95.22  ? 365 GLN C CD  1 
ATOM   6243 O OE1 . GLN C 1 365 ? 100.978 137.880 140.026 1.00 95.22  ? 365 GLN C OE1 1 
ATOM   6244 N NE2 . GLN C 1 365 ? 100.492 139.264 138.337 1.00 95.22  ? 365 GLN C NE2 1 
ATOM   6245 N N   . LEU C 1 366 ? 104.903 139.964 137.346 1.00 98.05  ? 366 LEU C N   1 
ATOM   6246 C CA  . LEU C 1 366 ? 104.963 140.692 136.083 1.00 98.05  ? 366 LEU C CA  1 
ATOM   6247 C C   . LEU C 1 366 ? 105.070 139.743 134.899 1.00 98.05  ? 366 LEU C C   1 
ATOM   6248 O O   . LEU C 1 366 ? 104.438 139.963 133.857 1.00 98.05  ? 366 LEU C O   1 
ATOM   6249 C CB  . LEU C 1 366 ? 106.128 141.683 136.086 1.00 98.05  ? 366 LEU C CB  1 
ATOM   6250 C CG  . LEU C 1 366 ? 105.929 143.082 136.676 1.00 98.05  ? 366 LEU C CG  1 
ATOM   6251 C CD1 . LEU C 1 366 ? 104.923 143.832 135.839 1.00 98.05  ? 366 LEU C CD1 1 
ATOM   6252 C CD2 . LEU C 1 366 ? 105.471 143.059 138.113 1.00 98.05  ? 366 LEU C CD2 1 
ATOM   6253 N N   . VAL C 1 367 ? 105.881 138.691 135.027 1.00 98.13  ? 367 VAL C N   1 
ATOM   6254 C CA  . VAL C 1 367 ? 105.942 137.710 133.949 1.00 98.13  ? 367 VAL C CA  1 
ATOM   6255 C C   . VAL C 1 367 ? 104.579 137.087 133.695 1.00 98.13  ? 367 VAL C C   1 
ATOM   6256 O O   . VAL C 1 367 ? 104.187 136.881 132.537 1.00 98.13  ? 367 VAL C O   1 
ATOM   6257 C CB  . VAL C 1 367 ? 106.986 136.631 134.267 1.00 98.13  ? 367 VAL C CB  1 
ATOM   6258 C CG1 . VAL C 1 367 ? 106.943 135.534 133.230 1.00 98.13  ? 367 VAL C CG1 1 
ATOM   6259 C CG2 . VAL C 1 367 ? 108.355 137.248 134.332 1.00 98.13  ? 367 VAL C CG2 1 
ATOM   6260 N N   . ASN C 1 368 ? 103.839 136.797 134.761 1.00 98.02  ? 368 ASN C N   1 
ATOM   6261 C CA  . ASN C 1 368 ? 102.499 136.254 134.613 1.00 98.02  ? 368 ASN C CA  1 
ATOM   6262 C C   . ASN C 1 368 ? 101.575 137.254 133.938 1.00 98.02  ? 368 ASN C C   1 
ATOM   6263 O O   . ASN C 1 368 ? 100.725 136.872 133.133 1.00 98.02  ? 368 ASN C O   1 
ATOM   6264 C CB  . ASN C 1 368 ? 101.964 135.857 135.981 1.00 98.02  ? 368 ASN C CB  1 
ATOM   6265 C CG  . ASN C 1 368 ? 102.518 134.540 136.452 1.00 98.02  ? 368 ASN C CG  1 
ATOM   6266 O OD1 . ASN C 1 368 ? 103.575 134.105 135.999 1.00 98.02  ? 368 ASN C OD1 1 
ATOM   6267 N ND2 . ASN C 1 368 ? 101.824 133.906 137.381 1.00 98.02  ? 368 ASN C ND2 1 
ATOM   6268 N N   . LEU C 1 369 ? 101.722 138.540 134.260 1.00 100.84 ? 369 LEU C N   1 
ATOM   6269 C CA  . LEU C 1 369 ? 100.920 139.565 133.598 1.00 100.84 ? 369 LEU C CA  1 
ATOM   6270 C C   . LEU C 1 369 ? 101.192 139.596 132.102 1.00 100.84 ? 369 LEU C C   1 
ATOM   6271 O O   . LEU C 1 369 ? 100.264 139.707 131.292 1.00 100.84 ? 369 LEU C O   1 
ATOM   6272 C CB  . LEU C 1 369 ? 101.205 140.933 134.210 1.00 100.84 ? 369 LEU C CB  1 
ATOM   6273 C CG  . LEU C 1 369 ? 100.800 141.187 135.656 1.00 100.84 ? 369 LEU C CG  1 
ATOM   6274 C CD1 . LEU C 1 369 ? 101.304 142.543 136.090 1.00 100.84 ? 369 LEU C CD1 1 
ATOM   6275 C CD2 . LEU C 1 369 ? 99.297  141.127 135.784 1.00 100.84 ? 369 LEU C CD2 1 
ATOM   6276 N N   . TYR C 1 370 ? 102.465 139.521 131.718 1.00 106.27 ? 370 TYR C N   1 
ATOM   6277 C CA  . TYR C 1 370 ? 102.819 139.530 130.299 1.00 106.27 ? 370 TYR C CA  1 
ATOM   6278 C C   . TYR C 1 370 ? 102.231 138.325 129.576 1.00 106.27 ? 370 TYR C C   1 
ATOM   6279 O O   . TYR C 1 370 ? 101.642 138.449 128.490 1.00 106.27 ? 370 TYR C O   1 
ATOM   6280 C CB  . TYR C 1 370 ? 104.341 139.563 130.157 1.00 106.27 ? 370 TYR C CB  1 
ATOM   6281 C CG  . TYR C 1 370 ? 104.851 139.328 128.759 1.00 106.27 ? 370 TYR C CG  1 
ATOM   6282 C CD1 . TYR C 1 370 ? 105.882 138.432 128.526 1.00 106.27 ? 370 TYR C CD1 1 
ATOM   6283 C CD2 . TYR C 1 370 ? 104.318 140.006 127.675 1.00 106.27 ? 370 TYR C CD2 1 
ATOM   6284 C CE1 . TYR C 1 370 ? 106.361 138.212 127.257 1.00 106.27 ? 370 TYR C CE1 1 
ATOM   6285 C CE2 . TYR C 1 370 ? 104.790 139.790 126.398 1.00 106.27 ? 370 TYR C CE2 1 
ATOM   6286 C CZ  . TYR C 1 370 ? 105.811 138.891 126.196 1.00 106.27 ? 370 TYR C CZ  1 
ATOM   6287 O OH  . TYR C 1 370 ? 106.291 138.668 124.931 1.00 106.27 ? 370 TYR C OH  1 
ATOM   6288 N N   . TRP C 1 371 ? 102.373 137.159 130.200 1.00 108.18 ? 371 TRP C N   1 
ATOM   6289 C CA  . TRP C 1 371 ? 101.838 135.926 129.645 1.00 108.18 ? 371 TRP C CA  1 
ATOM   6290 C C   . TRP C 1 371 ? 100.332 136.073 129.478 1.00 108.18 ? 371 TRP C C   1 
ATOM   6291 O O   . TRP C 1 371 ? 99.772  135.670 128.459 1.00 108.18 ? 371 TRP C O   1 
ATOM   6292 C CB  . TRP C 1 371 ? 102.160 134.740 130.554 1.00 108.18 ? 371 TRP C CB  1 
ATOM   6293 C CG  . TRP C 1 371 ? 103.106 133.755 129.940 1.00 108.18 ? 371 TRP C CG  1 
ATOM   6294 C CD1 . TRP C 1 371 ? 102.856 132.927 128.883 1.00 108.18 ? 371 TRP C CD1 1 
ATOM   6295 C CD2 . TRP C 1 371 ? 104.456 133.494 130.344 1.00 108.18 ? 371 TRP C CD2 1 
ATOM   6296 N NE1 . TRP C 1 371 ? 103.966 132.168 128.606 1.00 108.18 ? 371 TRP C NE1 1 
ATOM   6297 C CE2 . TRP C 1 371 ? 104.961 132.496 129.488 1.00 108.18 ? 371 TRP C CE2 1 
ATOM   6298 C CE3 . TRP C 1 371 ? 105.285 134.006 131.347 1.00 108.18 ? 371 TRP C CE3 1 
ATOM   6299 C CZ2 . TRP C 1 371 ? 106.258 132.000 129.603 1.00 108.18 ? 371 TRP C CZ2 1 
ATOM   6300 C CZ3 . TRP C 1 371 ? 106.573 133.513 131.459 1.00 108.18 ? 371 TRP C CZ3 1 
ATOM   6301 C CH2 . TRP C 1 371 ? 107.047 132.520 130.592 1.00 108.18 ? 371 TRP C CH2 1 
ATOM   6302 N N   . LEU C 1 372 ? 99.679  136.652 130.482 1.00 108.40 ? 372 LEU C N   1 
ATOM   6303 C CA  . LEU C 1 372 ? 98.238  136.859 130.410 1.00 108.40 ? 372 LEU C CA  1 
ATOM   6304 C C   . LEU C 1 372 ? 97.867  137.788 129.265 1.00 108.40 ? 372 LEU C C   1 
ATOM   6305 O O   . LEU C 1 372 ? 96.854  137.577 128.593 1.00 108.40 ? 372 LEU C O   1 
ATOM   6306 C CB  . LEU C 1 372 ? 97.709  137.417 131.728 1.00 108.40 ? 372 LEU C CB  1 
ATOM   6307 C CG  . LEU C 1 372 ? 96.191  137.579 131.735 1.00 108.40 ? 372 LEU C CG  1 
ATOM   6308 C CD1 . LEU C 1 372 ? 95.536  136.263 131.375 1.00 108.40 ? 372 LEU C CD1 1 
ATOM   6309 C CD2 . LEU C 1 372 ? 95.710  138.063 133.083 1.00 108.40 ? 372 LEU C CD2 1 
ATOM   6310 N N   . PHE C 1 373 ? 98.658  138.839 129.043 1.00 113.98 ? 373 PHE C N   1 
ATOM   6311 C CA  . PHE C 1 373 ? 98.384  139.736 127.923 1.00 113.98 ? 373 PHE C CA  1 
ATOM   6312 C C   . PHE C 1 373 ? 98.395  138.970 126.612 1.00 113.98 ? 373 PHE C C   1 
ATOM   6313 O O   . PHE C 1 373 ? 97.471  139.090 125.794 1.00 113.98 ? 373 PHE C O   1 
ATOM   6314 C CB  . PHE C 1 373 ? 99.405  140.873 127.872 1.00 113.98 ? 373 PHE C CB  1 
ATOM   6315 C CG  . PHE C 1 373 ? 99.218  141.911 128.940 1.00 113.98 ? 373 PHE C CG  1 
ATOM   6316 C CD1 . PHE C 1 373 ? 100.260 142.757 129.284 1.00 113.98 ? 373 PHE C CD1 1 
ATOM   6317 C CD2 . PHE C 1 373 ? 98.008  142.044 129.596 1.00 113.98 ? 373 PHE C CD2 1 
ATOM   6318 C CE1 . PHE C 1 373 ? 100.100 143.712 130.265 1.00 113.98 ? 373 PHE C CE1 1 
ATOM   6319 C CE2 . PHE C 1 373 ? 97.842  142.997 130.578 1.00 113.98 ? 373 PHE C CE2 1 
ATOM   6320 C CZ  . PHE C 1 373 ? 98.889  143.833 130.913 1.00 113.98 ? 373 PHE C CZ  1 
ATOM   6321 N N   . LEU C 1 374 ? 99.427  138.155 126.400 1.00 115.11 ? 374 LEU C N   1 
ATOM   6322 C CA  . LEU C 1 374 ? 99.467  137.429 125.136 1.00 115.11 ? 374 LEU C CA  1 
ATOM   6323 C C   . LEU C 1 374 ? 98.408  136.331 125.071 1.00 115.11 ? 374 LEU C C   1 
ATOM   6324 O O   . LEU C 1 374 ? 97.902  136.046 123.980 1.00 115.11 ? 374 LEU C O   1 
ATOM   6325 C CB  . LEU C 1 374 ? 100.862 136.867 124.863 1.00 115.11 ? 374 LEU C CB  1 
ATOM   6326 C CG  . LEU C 1 374 ? 101.466 135.680 125.598 1.00 115.11 ? 374 LEU C CG  1 
ATOM   6327 C CD1 . LEU C 1 374 ? 101.097 134.385 124.899 1.00 115.11 ? 374 LEU C CD1 1 
ATOM   6328 C CD2 . LEU C 1 374 ? 102.969 135.848 125.626 1.00 115.11 ? 374 LEU C CD2 1 
ATOM   6329 N N   . ILE C 1 375 ? 98.017  135.789 126.220 1.00 118.89 ? 375 ILE C N   1 
ATOM   6330 C CA  . ILE C 1 375 ? 96.970  134.779 126.256 1.00 118.89 ? 375 ILE C CA  1 
ATOM   6331 C C   . ILE C 1 375 ? 95.655  135.439 125.838 1.00 118.89 ? 375 ILE C C   1 
ATOM   6332 O O   . ILE C 1 375 ? 94.845  134.843 125.127 1.00 118.89 ? 375 ILE C O   1 
ATOM   6333 C CB  . ILE C 1 375 ? 96.813  134.170 127.660 1.00 118.89 ? 375 ILE C CB  1 
ATOM   6334 C CG1 . ILE C 1 375 ? 95.933  132.920 127.604 1.00 118.89 ? 375 ILE C CG1 1 
ATOM   6335 C CG2 . ILE C 1 375 ? 96.229  135.194 128.622 1.00 118.89 ? 375 ILE C CG2 1 
ATOM   6336 C CD1 . ILE C 1 375 ? 94.490  133.205 127.250 1.00 118.89 ? 375 ILE C CD1 1 
ATOM   6337 N N   . PHE C 1 376 ? 95.458  136.676 126.288 1.00 126.17 ? 376 PHE C N   1 
ATOM   6338 C CA  . PHE C 1 376 ? 94.273  137.455 125.966 1.00 126.17 ? 376 PHE C CA  1 
ATOM   6339 C C   . PHE C 1 376 ? 94.258  137.652 124.457 1.00 126.17 ? 376 PHE C C   1 
ATOM   6340 O O   . PHE C 1 376 ? 93.255  137.390 123.794 1.00 126.17 ? 376 PHE C O   1 
ATOM   6341 C CB  . PHE C 1 376 ? 94.302  138.806 126.680 1.00 126.17 ? 376 PHE C CB  1 
ATOM   6342 C CG  . PHE C 1 376 ? 92.940  139.351 127.002 1.00 126.17 ? 376 PHE C CG  1 
ATOM   6343 C CD1 . PHE C 1 376 ? 92.526  139.486 128.316 1.00 126.17 ? 376 PHE C CD1 1 
ATOM   6344 C CD2 . PHE C 1 376 ? 92.074  139.730 125.989 1.00 126.17 ? 376 PHE C CD2 1 
ATOM   6345 C CE1 . PHE C 1 376 ? 91.274  139.987 128.615 1.00 126.17 ? 376 PHE C CE1 1 
ATOM   6346 C CE2 . PHE C 1 376 ? 90.820  140.232 126.281 1.00 126.17 ? 376 PHE C CE2 1 
ATOM   6347 C CZ  . PHE C 1 376 ? 90.419  140.361 127.597 1.00 126.17 ? 376 PHE C CZ  1 
ATOM   6348 N N   . ARG C 1 377 ? 95.391  138.090 123.916 1.00 128.35 ? 377 ARG C N   1 
ATOM   6349 C CA  . ARG C 1 377 ? 95.521  138.308 122.481 1.00 128.35 ? 377 ARG C CA  1 
ATOM   6350 C C   . ARG C 1 377 ? 95.112  137.055 121.714 1.00 128.35 ? 377 ARG C C   1 
ATOM   6351 O O   . ARG C 1 377 ? 94.352  137.130 120.748 1.00 128.35 ? 377 ARG C O   1 
ATOM   6352 C CB  . ARG C 1 377 ? 96.956  138.700 122.126 1.00 128.35 ? 377 ARG C CB  1 
ATOM   6353 C CG  . ARG C 1 377 ? 97.207  138.841 120.634 1.00 128.35 ? 377 ARG C CG  1 
ATOM   6354 C CD  . ARG C 1 377 ? 98.453  139.669 120.360 1.00 128.35 ? 377 ARG C CD  1 
ATOM   6355 N NE  . ARG C 1 377 ? 99.511  139.402 121.330 1.00 128.35 ? 377 ARG C NE  1 
ATOM   6356 C CZ  . ARG C 1 377 ? 100.770 139.132 121.006 1.00 128.35 ? 377 ARG C CZ  1 
ATOM   6357 N NH1 . ARG C 1 377 ? 101.667 138.901 121.957 1.00 128.35 ? 377 ARG C NH1 1 
ATOM   6358 N NH2 . ARG C 1 377 ? 101.135 139.091 119.732 1.00 128.35 ? 377 ARG C NH2 1 
ATOM   6359 N N   . VAL C 1 378 ? 95.619  135.904 122.147 1.00 129.53 ? 378 VAL C N   1 
ATOM   6360 C CA  . VAL C 1 378 ? 95.293  134.639 121.496 1.00 129.53 ? 378 VAL C CA  1 
ATOM   6361 C C   . VAL C 1 378 ? 93.794  134.381 121.569 1.00 129.53 ? 378 VAL C C   1 
ATOM   6362 O O   . VAL C 1 378 ? 93.168  133.941 120.598 1.00 129.53 ? 378 VAL C O   1 
ATOM   6363 C CB  . VAL C 1 378 ? 96.093  133.489 122.135 1.00 129.53 ? 378 VAL C CB  1 
ATOM   6364 C CG1 . VAL C 1 378 ? 95.495  132.142 121.768 1.00 129.53 ? 378 VAL C CG1 1 
ATOM   6365 C CG2 . VAL C 1 378 ? 97.553  133.564 121.720 1.00 129.53 ? 378 VAL C CG2 1 
ATOM   6366 N N   . LEU C 1 379 ? 93.203  134.640 122.735 1.00 133.38 ? 379 LEU C N   1 
ATOM   6367 C CA  . LEU C 1 379 ? 91.778  134.411 122.928 1.00 133.38 ? 379 LEU C CA  1 
ATOM   6368 C C   . LEU C 1 379 ? 90.961  135.264 121.973 1.00 133.38 ? 379 LEU C C   1 
ATOM   6369 O O   . LEU C 1 379 ? 90.023  134.780 121.331 1.00 133.38 ? 379 LEU C O   1 
ATOM   6370 C CB  . LEU C 1 379 ? 91.392  134.715 124.374 1.00 133.38 ? 379 LEU C CB  1 
ATOM   6371 C CG  . LEU C 1 379 ? 89.932  134.457 124.741 1.00 133.38 ? 379 LEU C CG  1 
ATOM   6372 C CD1 . LEU C 1 379 ? 89.580  132.985 124.592 1.00 133.38 ? 379 LEU C CD1 1 
ATOM   6373 C CD2 . LEU C 1 379 ? 89.639  134.951 126.146 1.00 133.38 ? 379 LEU C CD2 1 
ATOM   6374 N N   . TYR C 1 380 ? 91.319  136.544 121.859 1.00 139.17 ? 380 TYR C N   1 
ATOM   6375 C CA  . TYR C 1 380 ? 90.635  137.442 120.933 1.00 139.17 ? 380 TYR C CA  1 
ATOM   6376 C C   . TYR C 1 380 ? 90.717  136.934 119.500 1.00 139.17 ? 380 TYR C C   1 
ATOM   6377 O O   . TYR C 1 380 ? 89.699  136.824 118.803 1.00 139.17 ? 380 TYR C O   1 
ATOM   6378 C CB  . TYR C 1 380 ? 91.246  138.839 121.035 1.00 139.17 ? 380 TYR C CB  1 
ATOM   6379 C CG  . TYR C 1 380 ? 90.866  139.769 119.908 1.00 139.17 ? 380 TYR C CG  1 
ATOM   6380 C CD1 . TYR C 1 380 ? 89.589  140.303 119.818 1.00 139.17 ? 380 TYR C CD1 1 
ATOM   6381 C CD2 . TYR C 1 380 ? 91.791  140.111 118.931 1.00 139.17 ? 380 TYR C CD2 1 
ATOM   6382 C CE1 . TYR C 1 380 ? 89.246  141.158 118.790 1.00 139.17 ? 380 TYR C CE1 1 
ATOM   6383 C CE2 . TYR C 1 380 ? 91.456  140.963 117.898 1.00 139.17 ? 380 TYR C CE2 1 
ATOM   6384 C CZ  . TYR C 1 380 ? 90.183  141.481 117.831 1.00 139.17 ? 380 TYR C CZ  1 
ATOM   6385 O OH  . TYR C 1 380 ? 89.844  142.330 116.802 1.00 139.17 ? 380 TYR C OH  1 
ATOM   6386 N N   . ARG C 1 381 ? 91.930  136.613 119.046 1.00 139.51 ? 381 ARG C N   1 
ATOM   6387 C CA  . ARG C 1 381 ? 92.088  136.201 117.655 1.00 139.51 ? 381 ARG C CA  1 
ATOM   6388 C C   . ARG C 1 381 ? 91.368  134.890 117.357 1.00 139.51 ? 381 ARG C C   1 
ATOM   6389 O O   . ARG C 1 381 ? 90.744  134.763 116.300 1.00 139.51 ? 381 ARG C O   1 
ATOM   6390 C CB  . ARG C 1 381 ? 93.569  136.111 117.298 1.00 139.51 ? 381 ARG C CB  1 
ATOM   6391 C CG  . ARG C 1 381 ? 94.237  137.473 117.275 1.00 139.51 ? 381 ARG C CG  1 
ATOM   6392 C CD  . ARG C 1 381 ? 95.707  137.402 116.916 1.00 139.51 ? 381 ARG C CD  1 
ATOM   6393 N NE  . ARG C 1 381 ? 96.306  138.733 116.923 1.00 139.51 ? 381 ARG C NE  1 
ATOM   6394 C CZ  . ARG C 1 381 ? 97.592  138.978 116.701 1.00 139.51 ? 381 ARG C CZ  1 
ATOM   6395 N NH1 . ARG C 1 381 ? 98.429  137.981 116.457 1.00 139.51 ? 381 ARG C NH1 1 
ATOM   6396 N NH2 . ARG C 1 381 ? 98.043  140.226 116.726 1.00 139.51 ? 381 ARG C NH2 1 
ATOM   6397 N N   . ILE C 1 382 ? 91.428  133.912 118.263 1.00 141.63 ? 382 ILE C N   1 
ATOM   6398 C CA  . ILE C 1 382 ? 90.710  132.663 118.021 1.00 141.63 ? 382 ILE C CA  1 
ATOM   6399 C C   . ILE C 1 382 ? 89.203  132.878 118.118 1.00 141.63 ? 382 ILE C C   1 
ATOM   6400 O O   . ILE C 1 382 ? 88.427  132.205 117.428 1.00 141.63 ? 382 ILE C O   1 
ATOM   6401 C CB  . ILE C 1 382 ? 91.219  131.561 118.972 1.00 141.63 ? 382 ILE C CB  1 
ATOM   6402 C CG1 . ILE C 1 382 ? 92.577  131.040 118.486 1.00 141.63 ? 382 ILE C CG1 1 
ATOM   6403 C CG2 . ILE C 1 382 ? 90.227  130.411 119.080 1.00 141.63 ? 382 ILE C CG2 1 
ATOM   6404 C CD1 . ILE C 1 382 ? 93.222  130.029 119.403 1.00 141.63 ? 382 ILE C CD1 1 
ATOM   6405 N N   . LEU C 1 383 ? 88.762  133.831 118.945 1.00 141.73 ? 383 LEU C N   1 
ATOM   6406 C CA  . LEU C 1 383 ? 87.347  134.176 119.000 1.00 141.73 ? 383 LEU C CA  1 
ATOM   6407 C C   . LEU C 1 383 ? 86.862  134.757 117.680 1.00 141.73 ? 383 LEU C C   1 
ATOM   6408 O O   . LEU C 1 383 ? 85.744  134.457 117.244 1.00 141.73 ? 383 LEU C O   1 
ATOM   6409 C CB  . LEU C 1 383 ? 87.102  135.161 120.148 1.00 141.73 ? 383 LEU C CB  1 
ATOM   6410 C CG  . LEU C 1 383 ? 85.673  135.556 120.538 1.00 141.73 ? 383 LEU C CG  1 
ATOM   6411 C CD1 . LEU C 1 383 ? 85.635  135.952 122.001 1.00 141.73 ? 383 LEU C CD1 1 
ATOM   6412 C CD2 . LEU C 1 383 ? 85.145  136.702 119.683 1.00 141.73 ? 383 LEU C CD2 1 
ATOM   6413 N N   . TRP C 1 384 ? 87.676  135.588 117.032 1.00 143.51 ? 384 TRP C N   1 
ATOM   6414 C CA  . TRP C 1 384 ? 87.311  136.165 115.746 1.00 143.51 ? 384 TRP C CA  1 
ATOM   6415 C C   . TRP C 1 384 ? 87.837  135.346 114.570 1.00 143.51 ? 384 TRP C C   1 
ATOM   6416 O O   . TRP C 1 384 ? 88.135  135.908 113.511 1.00 143.51 ? 384 TRP C O   1 
ATOM   6417 C CB  . TRP C 1 384 ? 87.796  137.611 115.655 1.00 143.51 ? 384 TRP C CB  1 
ATOM   6418 C CG  . TRP C 1 384 ? 86.851  138.567 116.306 1.00 143.51 ? 384 TRP C CG  1 
ATOM   6419 C CD1 . TRP C 1 384 ? 87.023  139.203 117.496 1.00 143.51 ? 384 TRP C CD1 1 
ATOM   6420 C CD2 . TRP C 1 384 ? 85.570  138.975 115.813 1.00 143.51 ? 384 TRP C CD2 1 
ATOM   6421 N NE1 . TRP C 1 384 ? 85.935  139.993 117.773 1.00 143.51 ? 384 TRP C NE1 1 
ATOM   6422 C CE2 . TRP C 1 384 ? 85.027  139.870 116.755 1.00 143.51 ? 384 TRP C CE2 1 
ATOM   6423 C CE3 . TRP C 1 384 ? 84.831  138.674 114.664 1.00 143.51 ? 384 TRP C CE3 1 
ATOM   6424 C CZ2 . TRP C 1 384 ? 83.780  140.468 116.585 1.00 143.51 ? 384 TRP C CZ2 1 
ATOM   6425 C CZ3 . TRP C 1 384 ? 83.594  139.269 114.496 1.00 143.51 ? 384 TRP C CZ3 1 
ATOM   6426 C CH2 . TRP C 1 384 ? 83.080  140.156 115.451 1.00 143.51 ? 384 TRP C CH2 1 
ATOM   6427 N N   . ARG C 1 385 ? 87.952  134.032 114.739 1.00 141.48 ? 385 ARG C N   1 
ATOM   6428 C CA  . ARG C 1 385 ? 88.362  133.137 113.663 1.00 141.48 ? 385 ARG C CA  1 
ATOM   6429 C C   . ARG C 1 385 ? 87.581  131.830 113.726 1.00 141.48 ? 385 ARG C C   1 
ATOM   6430 O O   . ARG C 1 385 ? 87.398  131.255 114.799 1.00 141.48 ? 385 ARG C O   1 
ATOM   6431 C CB  . ARG C 1 385 ? 89.860  132.856 113.731 1.00 141.48 ? 385 ARG C CB  1 
ATOM   6432 C CG  . ARG C 1 385 ? 90.720  133.986 113.209 1.00 141.48 ? 385 ARG C CG  1 
ATOM   6433 C CD  . ARG C 1 385 ? 92.195  133.716 113.463 1.00 141.48 ? 385 ARG C CD  1 
ATOM   6434 N NE  . ARG C 1 385 ? 93.069  134.690 112.813 1.00 141.48 ? 385 ARG C NE  1 
ATOM   6435 C CZ  . ARG C 1 385 ? 93.149  134.891 111.500 1.00 141.48 ? 385 ARG C CZ  1 
ATOM   6436 N NH1 . ARG C 1 385 ? 92.421  134.170 110.657 1.00 141.48 ? 385 ARG C NH1 1 
ATOM   6437 N NH2 . ARG C 1 385 ? 93.978  135.807 111.026 1.00 141.48 ? 385 ARG C NH2 1 
ATOM   6438 N N   . PRO D 2 18  ? 126.781 122.167 119.467 1.00 117.41 ? 18  PRO D N   1 
ATOM   6439 C CA  . PRO D 2 18  ? 127.241 121.552 120.720 1.00 117.41 ? 18  PRO D CA  1 
ATOM   6440 C C   . PRO D 2 18  ? 128.353 122.336 121.399 1.00 117.41 ? 18  PRO D C   1 
ATOM   6441 O O   . PRO D 2 18  ? 129.480 122.347 120.906 1.00 117.41 ? 18  PRO D O   1 
ATOM   6442 C CB  . PRO D 2 18  ? 127.750 120.179 120.269 1.00 117.41 ? 18  PRO D CB  1 
ATOM   6443 C CG  . PRO D 2 18  ? 128.128 120.366 118.840 1.00 117.41 ? 18  PRO D CG  1 
ATOM   6444 C CD  . PRO D 2 18  ? 127.163 121.373 118.285 1.00 117.41 ? 18  PRO D CD  1 
ATOM   6445 N N   . LYS D 2 19  ? 128.041 122.981 122.525 1.00 110.21 ? 19  LYS D N   1 
ATOM   6446 C CA  . LYS D 2 19  ? 129.025 123.792 123.248 1.00 110.21 ? 19  LYS D CA  1 
ATOM   6447 C C   . LYS D 2 19  ? 129.027 123.370 124.717 1.00 110.21 ? 19  LYS D C   1 
ATOM   6448 O O   . LYS D 2 19  ? 128.009 123.427 125.412 1.00 110.21 ? 19  LYS D O   1 
ATOM   6449 C CB  . LYS D 2 19  ? 128.766 125.286 123.066 1.00 110.21 ? 19  LYS D CB  1 
ATOM   6450 C CG  . LYS D 2 19  ? 127.478 125.800 123.650 1.00 110.21 ? 19  LYS D CG  1 
ATOM   6451 C CD  . LYS D 2 19  ? 127.365 127.295 123.439 1.00 110.21 ? 19  LYS D CD  1 
ATOM   6452 C CE  . LYS D 2 19  ? 127.093 127.607 121.984 1.00 110.21 ? 19  LYS D CE  1 
ATOM   6453 N NZ  . LYS D 2 19  ? 125.765 127.102 121.573 1.00 110.21 ? 19  LYS D NZ  1 
ATOM   6454 N N   . ILE D 2 20  ? 130.193 122.927 125.170 1.00 105.79 ? 20  ILE D N   1 
ATOM   6455 C CA  . ILE D 2 20  ? 130.387 122.445 126.529 1.00 105.79 ? 20  ILE D CA  1 
ATOM   6456 C C   . ILE D 2 20  ? 131.024 123.503 127.415 1.00 105.79 ? 20  ILE D C   1 
ATOM   6457 O O   . ILE D 2 20  ? 130.660 123.654 128.585 1.00 105.79 ? 20  ILE D O   1 
ATOM   6458 C CB  . ILE D 2 20  ? 131.220 121.144 126.500 1.00 105.79 ? 20  ILE D CB  1 
ATOM   6459 C CG1 . ILE D 2 20  ? 130.345 119.950 126.134 1.00 105.79 ? 20  ILE D CG1 1 
ATOM   6460 C CG2 . ILE D 2 20  ? 131.993 120.957 127.762 1.00 105.79 ? 20  ILE D CG2 1 
ATOM   6461 C CD1 . ILE D 2 20  ? 131.114 118.648 126.071 1.00 105.79 ? 20  ILE D CD1 1 
ATOM   6462 N N   . PHE D 2 21  ? 132.000 124.242 126.893 1.00 108.34 ? 21  PHE D N   1 
ATOM   6463 C CA  . PHE D 2 21  ? 132.671 125.222 127.733 1.00 108.34 ? 21  PHE D CA  1 
ATOM   6464 C C   . PHE D 2 21  ? 131.710 126.287 128.225 1.00 108.34 ? 21  PHE D C   1 
ATOM   6465 O O   . PHE D 2 21  ? 131.877 126.804 129.332 1.00 108.34 ? 21  PHE D O   1 
ATOM   6466 C CB  . PHE D 2 21  ? 133.834 125.865 126.991 1.00 108.34 ? 21  PHE D CB  1 
ATOM   6467 C CG  . PHE D 2 21  ? 134.736 126.659 127.878 1.00 108.34 ? 21  PHE D CG  1 
ATOM   6468 C CD1 . PHE D 2 21  ? 135.747 126.042 128.591 1.00 108.34 ? 21  PHE D CD1 1 
ATOM   6469 C CD2 . PHE D 2 21  ? 134.569 128.028 128.005 1.00 108.34 ? 21  PHE D CD2 1 
ATOM   6470 C CE1 . PHE D 2 21  ? 136.575 126.774 129.414 1.00 108.34 ? 21  PHE D CE1 1 
ATOM   6471 C CE2 . PHE D 2 21  ? 135.395 128.764 128.824 1.00 108.34 ? 21  PHE D CE2 1 
ATOM   6472 C CZ  . PHE D 2 21  ? 136.399 128.137 129.529 1.00 108.34 ? 21  PHE D CZ  1 
ATOM   6473 N N   . ASN D 2 22  ? 130.695 126.622 127.432 1.00 105.19 ? 22  ASN D N   1 
ATOM   6474 C CA  . ASN D 2 22  ? 129.665 127.533 127.913 1.00 105.19 ? 22  ASN D CA  1 
ATOM   6475 C C   . ASN D 2 22  ? 128.922 126.919 129.095 1.00 105.19 ? 22  ASN D C   1 
ATOM   6476 O O   . ASN D 2 22  ? 128.594 127.609 130.072 1.00 105.19 ? 22  ASN D O   1 
ATOM   6477 C CB  . ASN D 2 22  ? 128.705 127.860 126.770 1.00 105.19 ? 22  ASN D CB  1 
ATOM   6478 C CG  . ASN D 2 22  ? 127.733 128.962 127.114 1.00 105.19 ? 22  ASN D CG  1 
ATOM   6479 O OD1 . ASN D 2 22  ? 127.739 129.491 128.223 1.00 105.19 ? 22  ASN D OD1 1 
ATOM   6480 N ND2 . ASN D 2 22  ? 126.884 129.316 126.158 1.00 105.19 ? 22  ASN D ND2 1 
ATOM   6481 N N   . LEU D 2 23  ? 128.658 125.613 129.020 1.00 103.99 ? 23  LEU D N   1 
ATOM   6482 C CA  . LEU D 2 23  ? 128.006 124.910 130.118 1.00 103.99 ? 23  LEU D CA  1 
ATOM   6483 C C   . LEU D 2 23  ? 128.841 124.965 131.390 1.00 103.99 ? 23  LEU D C   1 
ATOM   6484 O O   . LEU D 2 23  ? 128.310 125.234 132.470 1.00 103.99 ? 23  LEU D O   1 
ATOM   6485 C CB  . LEU D 2 23  ? 127.742 123.460 129.725 1.00 103.99 ? 23  LEU D CB  1 
ATOM   6486 C CG  . LEU D 2 23  ? 127.187 122.572 130.830 1.00 103.99 ? 23  LEU D CG  1 
ATOM   6487 C CD1 . LEU D 2 23  ? 125.710 122.825 130.982 1.00 103.99 ? 23  LEU D CD1 1 
ATOM   6488 C CD2 . LEU D 2 23  ? 127.480 121.108 130.555 1.00 103.99 ? 23  LEU D CD2 1 
ATOM   6489 N N   . PHE D 2 24  ? 130.146 124.708 131.290 1.00 104.35 ? 24  PHE D N   1 
ATOM   6490 C CA  . PHE D 2 24  ? 130.973 124.846 132.485 1.00 104.35 ? 24  PHE D CA  1 
ATOM   6491 C C   . PHE D 2 24  ? 131.119 126.283 132.958 1.00 104.35 ? 24  PHE D C   1 
ATOM   6492 O O   . PHE D 2 24  ? 131.252 126.494 134.160 1.00 104.35 ? 24  PHE D O   1 
ATOM   6493 C CB  . PHE D 2 24  ? 132.354 124.218 132.312 1.00 104.35 ? 24  PHE D CB  1 
ATOM   6494 C CG  . PHE D 2 24  ? 132.332 122.725 132.208 1.00 104.35 ? 24  PHE D CG  1 
ATOM   6495 C CD1 . PHE D 2 24  ? 132.236 121.960 133.356 1.00 104.35 ? 24  PHE D CD1 1 
ATOM   6496 C CD2 . PHE D 2 24  ? 132.419 122.078 130.997 1.00 104.35 ? 24  PHE D CD2 1 
ATOM   6497 C CE1 . PHE D 2 24  ? 132.224 120.592 133.296 1.00 104.35 ? 24  PHE D CE1 1 
ATOM   6498 C CE2 . PHE D 2 24  ? 132.406 120.699 130.947 1.00 104.35 ? 24  PHE D CE2 1 
ATOM   6499 C CZ  . PHE D 2 24  ? 132.309 119.960 132.092 1.00 104.35 ? 24  PHE D CZ  1 
ATOM   6500 N N   . ARG D 2 25  ? 131.000 127.244 132.048 1.00 103.80 ? 25  ARG D N   1 
ATOM   6501 C CA  . ARG D 2 25  ? 131.084 128.652 132.414 1.00 103.80 ? 25  ARG D CA  1 
ATOM   6502 C C   . ARG D 2 25  ? 129.886 129.052 133.279 1.00 103.80 ? 25  ARG D C   1 
ATOM   6503 O O   . ARG D 2 25  ? 130.043 129.751 134.280 1.00 103.80 ? 25  ARG D O   1 
ATOM   6504 C CB  . ARG D 2 25  ? 131.148 129.530 131.163 1.00 103.80 ? 25  ARG D CB  1 
ATOM   6505 C CG  . ARG D 2 25  ? 132.027 130.761 131.314 1.00 103.80 ? 25  ARG D CG  1 
ATOM   6506 C CD  . ARG D 2 25  ? 131.587 131.871 130.373 1.00 103.80 ? 25  ARG D CD  1 
ATOM   6507 N NE  . ARG D 2 25  ? 131.273 131.366 129.040 1.00 103.80 ? 25  ARG D NE  1 
ATOM   6508 C CZ  . ARG D 2 25  ? 130.059 131.387 128.500 1.00 103.80 ? 25  ARG D CZ  1 
ATOM   6509 N NH1 . ARG D 2 25  ? 129.866 130.904 127.280 1.00 103.80 ? 25  ARG D NH1 1 
ATOM   6510 N NH2 . ARG D 2 25  ? 129.037 131.889 129.180 1.00 103.80 ? 25  ARG D NH2 1 
ATOM   6511 N N   . VAL D 2 26  ? 128.693 128.606 132.891 1.00 99.04  ? 26  VAL D N   1 
ATOM   6512 C CA  . VAL D 2 26  ? 127.475 128.914 133.640 1.00 99.04  ? 26  VAL D CA  1 
ATOM   6513 C C   . VAL D 2 26  ? 127.378 128.059 134.902 1.00 99.04  ? 26  VAL D C   1 
ATOM   6514 O O   . VAL D 2 26  ? 126.959 128.550 135.957 1.00 99.04  ? 26  VAL D O   1 
ATOM   6515 C CB  . VAL D 2 26  ? 126.227 128.778 132.744 1.00 99.04  ? 26  VAL D CB  1 
ATOM   6516 C CG1 . VAL D 2 26  ? 126.019 127.348 132.284 1.00 99.04  ? 26  VAL D CG1 1 
ATOM   6517 C CG2 . VAL D 2 26  ? 124.997 129.287 133.468 1.00 99.04  ? 26  VAL D CG2 1 
ATOM   6518 N N   . CYS D 2 27  ? 127.782 126.788 134.837 1.00 96.38  ? 27  CYS D N   1 
ATOM   6519 C CA  . CYS D 2 27  ? 127.784 125.937 136.019 1.00 96.38  ? 27  CYS D CA  1 
ATOM   6520 C C   . CYS D 2 27  ? 128.789 126.383 137.069 1.00 96.38  ? 27  CYS D C   1 
ATOM   6521 O O   . CYS D 2 27  ? 128.472 126.346 138.259 1.00 96.38  ? 27  CYS D O   1 
ATOM   6522 C CB  . CYS D 2 27  ? 128.073 124.489 135.630 1.00 96.38  ? 27  CYS D CB  1 
ATOM   6523 S SG  . CYS D 2 27  ? 128.253 123.376 137.032 1.00 96.38  ? 27  CYS D SG  1 
ATOM   6524 N N   . PHE D 2 28  ? 129.987 126.799 136.663 1.00 96.59  ? 28  PHE D N   1 
ATOM   6525 C CA  . PHE D 2 28  ? 130.970 127.309 137.605 1.00 96.59  ? 28  PHE D CA  1 
ATOM   6526 C C   . PHE D 2 28  ? 130.488 128.591 138.256 1.00 96.59  ? 28  PHE D C   1 
ATOM   6527 O O   . PHE D 2 28  ? 130.665 128.780 139.462 1.00 96.59  ? 28  PHE D O   1 
ATOM   6528 C CB  . PHE D 2 28  ? 132.296 127.543 136.887 1.00 96.59  ? 28  PHE D CB  1 
ATOM   6529 C CG  . PHE D 2 28  ? 133.428 127.885 137.800 1.00 96.59  ? 28  PHE D CG  1 
ATOM   6530 C CD1 . PHE D 2 28  ? 133.892 126.965 138.723 1.00 96.59  ? 28  PHE D CD1 1 
ATOM   6531 C CD2 . PHE D 2 28  ? 134.028 129.128 137.738 1.00 96.59  ? 28  PHE D CD2 1 
ATOM   6532 C CE1 . PHE D 2 28  ? 134.940 127.278 139.562 1.00 96.59  ? 28  PHE D CE1 1 
ATOM   6533 C CE2 . PHE D 2 28  ? 135.072 129.448 138.577 1.00 96.59  ? 28  PHE D CE2 1 
ATOM   6534 C CZ  . PHE D 2 28  ? 135.530 128.522 139.490 1.00 96.59  ? 28  PHE D CZ  1 
ATOM   6535 N N   . ILE D 2 29  ? 129.872 129.484 137.480 1.00 91.63  ? 29  ILE D N   1 
ATOM   6536 C CA  . ILE D 2 29  ? 129.342 130.709 138.065 1.00 91.63  ? 29  ILE D CA  1 
ATOM   6537 C C   . ILE D 2 29  ? 128.240 130.396 139.069 1.00 91.63  ? 29  ILE D C   1 
ATOM   6538 O O   . ILE D 2 29  ? 128.218 130.943 140.178 1.00 91.63  ? 29  ILE D O   1 
ATOM   6539 C CB  . ILE D 2 29  ? 128.853 131.652 136.956 1.00 91.63  ? 29  ILE D CB  1 
ATOM   6540 C CG1 . ILE D 2 29  ? 130.047 132.238 136.207 1.00 91.63  ? 29  ILE D CG1 1 
ATOM   6541 C CG2 . ILE D 2 29  ? 127.989 132.749 137.539 1.00 91.63  ? 29  ILE D CG2 1 
ATOM   6542 C CD1 . ILE D 2 29  ? 130.767 133.324 136.963 1.00 91.63  ? 29  ILE D CD1 1 
ATOM   6543 N N   . SER D 2 30  ? 127.317 129.503 138.707 1.00 85.78  ? 30  SER D N   1 
ATOM   6544 C CA  . SER D 2 30  ? 126.230 129.156 139.615 1.00 85.78  ? 30  SER D CA  1 
ATOM   6545 C C   . SER D 2 30  ? 126.761 128.505 140.883 1.00 85.78  ? 30  SER D C   1 
ATOM   6546 O O   . SER D 2 30  ? 126.325 128.829 141.992 1.00 85.78  ? 30  SER D O   1 
ATOM   6547 C CB  . SER D 2 30  ? 125.249 128.219 138.917 1.00 85.78  ? 30  SER D CB  1 
ATOM   6548 O OG  . SER D 2 30  ? 125.778 126.906 138.858 1.00 85.78  ? 30  SER D OG  1 
ATOM   6549 N N   . LEU D 2 31  ? 127.701 127.574 140.733 1.00 81.74  ? 31  LEU D N   1 
ATOM   6550 C CA  . LEU D 2 31  ? 128.245 126.872 141.885 1.00 81.74  ? 31  LEU D CA  1 
ATOM   6551 C C   . LEU D 2 31  ? 129.020 127.818 142.788 1.00 81.74  ? 31  LEU D C   1 
ATOM   6552 O O   . LEU D 2 31  ? 128.933 127.725 144.018 1.00 81.74  ? 31  LEU D O   1 
ATOM   6553 C CB  . LEU D 2 31  ? 129.131 125.733 141.400 1.00 81.74  ? 31  LEU D CB  1 
ATOM   6554 C CG  . LEU D 2 31  ? 129.741 124.824 142.449 1.00 81.74  ? 31  LEU D CG  1 
ATOM   6555 C CD1 . LEU D 2 31  ? 128.621 124.131 143.177 1.00 81.74  ? 31  LEU D CD1 1 
ATOM   6556 C CD2 . LEU D 2 31  ? 130.659 123.817 141.795 1.00 81.74  ? 31  LEU D CD2 1 
ATOM   6557 N N   . LEU D 2 32  ? 129.774 128.743 142.200 1.00 80.32  ? 32  LEU D N   1 
ATOM   6558 C CA  . LEU D 2 32  ? 130.487 129.726 142.997 1.00 80.32  ? 32  LEU D CA  1 
ATOM   6559 C C   . LEU D 2 32  ? 129.520 130.638 143.731 1.00 80.32  ? 32  LEU D C   1 
ATOM   6560 O O   . LEU D 2 32  ? 129.788 131.040 144.862 1.00 80.32  ? 32  LEU D O   1 
ATOM   6561 C CB  . LEU D 2 32  ? 131.427 130.533 142.107 1.00 80.32  ? 32  LEU D CB  1 
ATOM   6562 C CG  . LEU D 2 32  ? 132.400 131.473 142.811 1.00 80.32  ? 32  LEU D CG  1 
ATOM   6563 C CD1 . LEU D 2 32  ? 133.724 131.467 142.078 1.00 80.32  ? 32  LEU D CD1 1 
ATOM   6564 C CD2 . LEU D 2 32  ? 131.842 132.882 142.874 1.00 80.32  ? 32  LEU D CD2 1 
ATOM   6565 N N   . LEU D 2 33  ? 128.398 130.992 143.108 1.00 76.69  ? 33  LEU D N   1 
ATOM   6566 C CA  . LEU D 2 33  ? 127.414 131.814 143.806 1.00 76.69  ? 33  LEU D CA  1 
ATOM   6567 C C   . LEU D 2 33  ? 126.772 131.044 144.956 1.00 76.69  ? 33  LEU D C   1 
ATOM   6568 O O   . LEU D 2 33  ? 126.509 131.610 146.026 1.00 76.69  ? 33  LEU D O   1 
ATOM   6569 C CB  . LEU D 2 33  ? 126.363 132.307 142.818 1.00 76.69  ? 33  LEU D CB  1 
ATOM   6570 C CG  . LEU D 2 33  ? 125.183 133.074 143.394 1.00 76.69  ? 33  LEU D CG  1 
ATOM   6571 C CD1 . LEU D 2 33  ? 125.582 134.507 143.638 1.00 76.69  ? 33  LEU D CD1 1 
ATOM   6572 C CD2 . LEU D 2 33  ? 124.020 133.011 142.436 1.00 76.69  ? 33  LEU D CD2 1 
ATOM   6573 N N   . ILE D 2 34  ? 126.515 129.751 144.750 1.00 75.66  ? 34  ILE D N   1 
ATOM   6574 C CA  . ILE D 2 34  ? 126.008 128.906 145.827 1.00 75.66  ? 34  ILE D CA  1 
ATOM   6575 C C   . ILE D 2 34  ? 126.978 128.898 146.996 1.00 75.66  ? 34  ILE D C   1 
ATOM   6576 O O   . ILE D 2 34  ? 126.579 129.042 148.155 1.00 75.66  ? 34  ILE D O   1 
ATOM   6577 C CB  . ILE D 2 34  ? 125.751 127.478 145.318 1.00 75.66  ? 34  ILE D CB  1 
ATOM   6578 C CG1 . ILE D 2 34  ? 124.476 127.416 144.485 1.00 75.66  ? 34  ILE D CG1 1 
ATOM   6579 C CG2 . ILE D 2 34  ? 125.673 126.513 146.474 1.00 75.66  ? 34  ILE D CG2 1 
ATOM   6580 C CD1 . ILE D 2 34  ? 124.203 126.041 143.924 1.00 75.66  ? 34  ILE D CD1 1 
ATOM   6581 N N   . ALA D 2 35  ? 128.264 128.724 146.712 1.00 73.09  ? 35  ALA D N   1 
ATOM   6582 C CA  . ALA D 2 35  ? 129.284 128.736 147.749 1.00 73.09  ? 35  ALA D CA  1 
ATOM   6583 C C   . ALA D 2 35  ? 129.486 130.111 148.362 1.00 73.09  ? 35  ALA D C   1 
ATOM   6584 O O   . ALA D 2 35  ? 129.920 130.204 149.511 1.00 73.09  ? 35  ALA D O   1 
ATOM   6585 C CB  . ALA D 2 35  ? 130.612 128.228 147.193 1.00 73.09  ? 35  ALA D CB  1 
ATOM   6586 N N   . ALA D 2 36  ? 129.192 131.177 147.628 1.00 72.55  ? 36  ALA D N   1 
ATOM   6587 C CA  . ALA D 2 36  ? 129.320 132.518 148.175 1.00 72.55  ? 36  ALA D CA  1 
ATOM   6588 C C   . ALA D 2 36  ? 128.222 132.808 149.182 1.00 72.55  ? 36  ALA D C   1 
ATOM   6589 O O   . ALA D 2 36  ? 128.486 133.358 150.251 1.00 72.55  ? 36  ALA D O   1 
ATOM   6590 C CB  . ALA D 2 36  ? 129.293 133.551 147.051 1.00 72.55  ? 36  ALA D CB  1 
ATOM   6591 N N   . VAL D 2 37  ? 126.981 132.439 148.860 1.00 70.90  ? 37  VAL D N   1 
ATOM   6592 C CA  . VAL D 2 37  ? 125.893 132.651 149.809 1.00 70.90  ? 37  VAL D CA  1 
ATOM   6593 C C   . VAL D 2 37  ? 126.023 131.759 151.036 1.00 70.90  ? 37  VAL D C   1 
ATOM   6594 O O   . VAL D 2 37  ? 125.715 132.197 152.151 1.00 70.90  ? 37  VAL D O   1 
ATOM   6595 C CB  . VAL D 2 37  ? 124.538 132.449 149.120 1.00 70.90  ? 37  VAL D CB  1 
ATOM   6596 C CG1 . VAL D 2 37  ? 123.428 132.497 150.128 1.00 70.90  ? 37  VAL D CG1 1 
ATOM   6597 C CG2 . VAL D 2 37  ? 124.333 133.535 148.107 1.00 70.90  ? 37  VAL D CG2 1 
ATOM   6598 N N   . GLU D 2 38  ? 126.531 130.548 150.835 1.00 72.40  ? 38  GLU D N   1 
ATOM   6599 C CA  . GLU D 2 38  ? 126.743 129.616 151.930 1.00 72.40  ? 38  GLU D CA  1 
ATOM   6600 C C   . GLU D 2 38  ? 127.739 130.220 152.915 1.00 72.40  ? 38  GLU D C   1 
ATOM   6601 O O   . GLU D 2 38  ? 127.541 130.151 154.128 1.00 72.40  ? 38  GLU D O   1 
ATOM   6602 C CB  . GLU D 2 38  ? 127.263 128.276 151.406 1.00 72.40  ? 38  GLU D CB  1 
ATOM   6603 C CG  . GLU D 2 38  ? 126.228 127.163 151.416 1.00 72.40  ? 38  GLU D CG  1 
ATOM   6604 C CD  . GLU D 2 38  ? 124.809 127.686 151.308 1.00 72.40  ? 38  GLU D CD  1 
ATOM   6605 O OE1 . GLU D 2 38  ? 124.356 128.377 152.244 1.00 72.40  ? 38  GLU D OE1 1 
ATOM   6606 O OE2 . GLU D 2 38  ? 124.146 127.407 150.286 1.00 72.40  ? 38  GLU D OE2 1 
ATOM   6607 N N   . TYR D 2 39  ? 128.810 130.814 152.390 1.00 72.47  ? 39  TYR D N   1 
ATOM   6608 C CA  . TYR D 2 39  ? 129.811 131.436 153.242 1.00 72.47  ? 39  TYR D CA  1 
ATOM   6609 C C   . TYR D 2 39  ? 129.299 132.740 153.828 1.00 72.47  ? 39  TYR D C   1 
ATOM   6610 O O   . TYR D 2 39  ? 129.704 133.124 154.921 1.00 72.47  ? 39  TYR D O   1 
ATOM   6611 C CB  . TYR D 2 39  ? 131.112 131.682 152.488 1.00 72.47  ? 39  TYR D CB  1 
ATOM   6612 C CG  . TYR D 2 39  ? 132.022 132.597 153.265 1.00 72.47  ? 39  TYR D CG  1 
ATOM   6613 C CD1 . TYR D 2 39  ? 132.150 133.934 152.938 1.00 72.47  ? 39  TYR D CD1 1 
ATOM   6614 C CD2 . TYR D 2 39  ? 132.719 132.127 154.364 1.00 72.47  ? 39  TYR D CD2 1 
ATOM   6615 C CE1 . TYR D 2 39  ? 132.963 134.760 153.665 1.00 72.47  ? 39  TYR D CE1 1 
ATOM   6616 C CE2 . TYR D 2 39  ? 133.534 132.949 155.094 1.00 72.47  ? 39  TYR D CE2 1 
ATOM   6617 C CZ  . TYR D 2 39  ? 133.651 134.265 154.742 1.00 72.47  ? 39  TYR D CZ  1 
ATOM   6618 O OH  . TYR D 2 39  ? 134.469 135.086 155.474 1.00 72.47  ? 39  TYR D OH  1 
ATOM   6619 N N   . PHE D 2 40  ? 128.428 133.451 153.116 1.00 69.40  ? 40  PHE D N   1 
ATOM   6620 C CA  . PHE D 2 40  ? 127.827 134.648 153.696 1.00 69.40  ? 40  PHE D CA  1 
ATOM   6621 C C   . PHE D 2 40  ? 127.036 134.300 154.940 1.00 69.40  ? 40  PHE D C   1 
ATOM   6622 O O   . PHE D 2 40  ? 127.178 134.944 155.983 1.00 69.40  ? 40  PHE D O   1 
ATOM   6623 C CB  . PHE D 2 40  ? 126.922 135.339 152.682 1.00 69.40  ? 40  PHE D CB  1 
ATOM   6624 C CG  . PHE D 2 40  ? 125.892 136.238 153.305 1.00 69.40  ? 40  PHE D CG  1 
ATOM   6625 C CD1 . PHE D 2 40  ? 126.215 137.520 153.684 1.00 69.40  ? 40  PHE D CD1 1 
ATOM   6626 C CD2 . PHE D 2 40  ? 124.598 135.800 153.504 1.00 69.40  ? 40  PHE D CD2 1 
ATOM   6627 C CE1 . PHE D 2 40  ? 125.268 138.344 154.251 1.00 69.40  ? 40  PHE D CE1 1 
ATOM   6628 C CE2 . PHE D 2 40  ? 123.653 136.621 154.071 1.00 69.40  ? 40  PHE D CE2 1 
ATOM   6629 C CZ  . PHE D 2 40  ? 123.988 137.890 154.443 1.00 69.40  ? 40  PHE D CZ  1 
ATOM   6630 N N   . LYS D 2 41  ? 126.187 133.280 154.846 1.00 64.97  ? 41  LYS D N   1 
ATOM   6631 C CA  . LYS D 2 41  ? 125.413 132.867 156.009 1.00 64.97  ? 41  LYS D CA  1 
ATOM   6632 C C   . LYS D 2 41  ? 126.328 132.445 157.146 1.00 64.97  ? 41  LYS D C   1 
ATOM   6633 O O   . LYS D 2 41  ? 126.158 132.884 158.289 1.00 64.97  ? 41  LYS D O   1 
ATOM   6634 C CB  . LYS D 2 41  ? 124.464 131.734 155.630 1.00 64.97  ? 41  LYS D CB  1 
ATOM   6635 C CG  . LYS D 2 41  ? 123.268 132.178 154.822 1.00 64.97  ? 41  LYS D CG  1 
ATOM   6636 C CD  . LYS D 2 41  ? 122.206 131.112 154.789 1.00 64.97  ? 41  LYS D CD  1 
ATOM   6637 C CE  . LYS D 2 41  ? 122.781 129.789 154.377 1.00 64.97  ? 41  LYS D CE  1 
ATOM   6638 N NZ  . LYS D 2 41  ? 121.926 128.681 154.842 1.00 64.97  ? 41  LYS D NZ  1 
ATOM   6639 N N   . TYR D 2 42  ? 127.333 131.622 156.846 1.00 65.20  ? 42  TYR D N   1 
ATOM   6640 C CA  . TYR D 2 42  ? 128.251 131.175 157.886 1.00 65.20  ? 42  TYR D CA  1 
ATOM   6641 C C   . TYR D 2 42  ? 129.042 132.319 158.503 1.00 65.20  ? 42  TYR D C   1 
ATOM   6642 O O   . TYR D 2 42  ? 129.207 132.364 159.725 1.00 65.20  ? 42  TYR D O   1 
ATOM   6643 C CB  . TYR D 2 42  ? 129.203 130.134 157.313 1.00 65.20  ? 42  TYR D CB  1 
ATOM   6644 C CG  . TYR D 2 42  ? 130.219 129.624 158.293 1.00 65.20  ? 42  TYR D CG  1 
ATOM   6645 C CD1 . TYR D 2 42  ? 131.513 130.106 158.295 1.00 65.20  ? 42  TYR D CD1 1 
ATOM   6646 C CD2 . TYR D 2 42  ? 129.884 128.653 159.216 1.00 65.20  ? 42  TYR D CD2 1 
ATOM   6647 C CE1 . TYR D 2 42  ? 132.440 129.637 159.184 1.00 65.20  ? 42  TYR D CE1 1 
ATOM   6648 C CE2 . TYR D 2 42  ? 130.803 128.181 160.110 1.00 65.20  ? 42  TYR D CE2 1 
ATOM   6649 C CZ  . TYR D 2 42  ? 132.080 128.674 160.091 1.00 65.20  ? 42  TYR D CZ  1 
ATOM   6650 O OH  . TYR D 2 42  ? 133.001 128.196 160.989 1.00 65.20  ? 42  TYR D OH  1 
ATOM   6651 N N   . GLY D 2 43  ? 129.541 133.240 157.686 1.00 65.24  ? 43  GLY D N   1 
ATOM   6652 C CA  . GLY D 2 43  ? 130.326 134.341 158.207 1.00 65.24  ? 43  GLY D CA  1 
ATOM   6653 C C   . GLY D 2 43  ? 129.510 135.281 159.063 1.00 65.24  ? 43  GLY D C   1 
ATOM   6654 O O   . GLY D 2 43  ? 129.953 135.707 160.129 1.00 65.24  ? 43  GLY D O   1 
ATOM   6655 N N   . THR D 2 44  ? 128.311 135.632 158.607 1.00 61.89  ? 44  THR D N   1 
ATOM   6656 C CA  . THR D 2 44  ? 127.461 136.466 159.440 1.00 61.89  ? 44  THR D CA  1 
ATOM   6657 C C   . THR D 2 44  ? 126.933 135.731 160.657 1.00 61.89  ? 44  THR D C   1 
ATOM   6658 O O   . THR D 2 44  ? 126.443 136.382 161.579 1.00 61.89  ? 44  THR D O   1 
ATOM   6659 C CB  . THR D 2 44  ? 126.288 137.015 158.642 1.00 61.89  ? 44  THR D CB  1 
ATOM   6660 O OG1 . THR D 2 44  ? 125.412 135.943 158.292 1.00 61.89  ? 44  THR D OG1 1 
ATOM   6661 C CG2 . THR D 2 44  ? 126.774 137.701 157.398 1.00 61.89  ? 44  THR D CG2 1 
ATOM   6662 N N   . ARG D 2 45  ? 127.011 134.407 160.695 1.00 61.68  ? 45  ARG D N   1 
ATOM   6663 C CA  . ARG D 2 45  ? 126.591 133.714 161.903 1.00 61.68  ? 45  ARG D CA  1 
ATOM   6664 C C   . ARG D 2 45  ? 127.703 133.556 162.928 1.00 61.68  ? 45  ARG D C   1 
ATOM   6665 O O   . ARG D 2 45  ? 127.446 133.722 164.122 1.00 61.68  ? 45  ARG D O   1 
ATOM   6666 C CB  . ARG D 2 45  ? 126.023 132.339 161.559 1.00 61.68  ? 45  ARG D CB  1 
ATOM   6667 C CG  . ARG D 2 45  ? 125.294 131.705 162.701 1.00 61.68  ? 45  ARG D CG  1 
ATOM   6668 C CD  . ARG D 2 45  ? 125.198 130.223 162.523 1.00 61.68  ? 45  ARG D CD  1 
ATOM   6669 N NE  . ARG D 2 45  ? 126.473 129.570 162.763 1.00 61.68  ? 45  ARG D NE  1 
ATOM   6670 C CZ  . ARG D 2 45  ? 127.027 128.704 161.928 1.00 61.68  ? 45  ARG D CZ  1 
ATOM   6671 N NH1 . ARG D 2 45  ? 128.193 128.151 162.222 1.00 61.68  ? 45  ARG D NH1 1 
ATOM   6672 N NH2 . ARG D 2 45  ? 126.413 128.386 160.799 1.00 61.68  ? 45  ARG D NH2 1 
ATOM   6673 N N   . ILE D 2 46  ? 128.926 133.231 162.511 1.00 63.22  ? 46  ILE D N   1 
ATOM   6674 C CA  . ILE D 2 46  ? 129.996 133.088 163.493 1.00 63.22  ? 46  ILE D CA  1 
ATOM   6675 C C   . ILE D 2 46  ? 130.416 134.421 164.089 1.00 63.22  ? 46  ILE D C   1 
ATOM   6676 O O   . ILE D 2 46  ? 130.702 134.483 165.288 1.00 63.22  ? 46  ILE D O   1 
ATOM   6677 C CB  . ILE D 2 46  ? 131.227 132.363 162.927 1.00 63.22  ? 46  ILE D CB  1 
ATOM   6678 C CG1 . ILE D 2 46  ? 131.840 133.140 161.771 1.00 63.22  ? 46  ILE D CG1 1 
ATOM   6679 C CG2 . ILE D 2 46  ? 130.891 130.944 162.551 1.00 63.22  ? 46  ILE D CG2 1 
ATOM   6680 C CD1 . ILE D 2 46  ? 133.167 132.601 161.334 1.00 63.22  ? 46  ILE D CD1 1 
ATOM   6681 N N   . ASN D 2 47  ? 130.475 135.488 163.305 1.00 62.34  ? 47  ASN D N   1 
ATOM   6682 C CA  . ASN D 2 47  ? 130.772 136.812 163.832 1.00 62.34  ? 47  ASN D CA  1 
ATOM   6683 C C   . ASN D 2 47  ? 129.613 137.744 163.492 1.00 62.34  ? 47  ASN D C   1 
ATOM   6684 O O   . ASN D 2 47  ? 129.660 138.545 162.564 1.00 62.34  ? 47  ASN D O   1 
ATOM   6685 C CB  . ASN D 2 47  ? 132.111 137.323 163.311 1.00 62.34  ? 47  ASN D CB  1 
ATOM   6686 C CG  . ASN D 2 47  ? 132.246 137.190 161.816 1.00 62.34  ? 47  ASN D CG  1 
ATOM   6687 O OD1 . ASN D 2 47  ? 132.967 136.335 161.317 1.00 62.34  ? 47  ASN D OD1 1 
ATOM   6688 N ND2 . ASN D 2 47  ? 131.545 138.046 161.088 1.00 62.34  ? 47  ASN D ND2 1 
ATOM   6689 N N   . TYR D 2 48  ? 128.574 137.659 164.308 1.00 57.86  ? 48  TYR D N   1 
ATOM   6690 C CA  . TYR D 2 48  ? 127.358 138.429 164.135 1.00 57.86  ? 48  TYR D CA  1 
ATOM   6691 C C   . TYR D 2 48  ? 127.388 139.735 164.892 1.00 57.86  ? 48  TYR D C   1 
ATOM   6692 O O   . TYR D 2 48  ? 126.736 140.691 164.470 1.00 57.86  ? 48  TYR D O   1 
ATOM   6693 C CB  . TYR D 2 48  ? 126.160 137.613 164.597 1.00 57.86  ? 48  TYR D CB  1 
ATOM   6694 C CG  . TYR D 2 48  ? 126.122 137.365 166.081 1.00 57.86  ? 48  TYR D CG  1 
ATOM   6695 C CD1 . TYR D 2 48  ? 125.396 138.183 166.921 1.00 57.86  ? 48  TYR D CD1 1 
ATOM   6696 C CD2 . TYR D 2 48  ? 126.813 136.311 166.642 1.00 57.86  ? 48  TYR D CD2 1 
ATOM   6697 C CE1 . TYR D 2 48  ? 125.358 137.960 168.267 1.00 57.86  ? 48  TYR D CE1 1 
ATOM   6698 C CE2 . TYR D 2 48  ? 126.781 136.081 167.989 1.00 57.86  ? 48  TYR D CE2 1 
ATOM   6699 C CZ  . TYR D 2 48  ? 126.051 136.910 168.794 1.00 57.86  ? 48  TYR D CZ  1 
ATOM   6700 O OH  . TYR D 2 48  ? 126.013 136.688 170.143 1.00 57.86  ? 48  TYR D OH  1 
ATOM   6701 N N   . GLU D 2 49  ? 128.137 139.805 165.985 1.00 61.96  ? 49  GLU D N   1 
ATOM   6702 C CA  . GLU D 2 49  ? 128.158 140.993 166.817 1.00 61.96  ? 49  GLU D CA  1 
ATOM   6703 C C   . GLU D 2 49  ? 128.675 142.210 166.078 1.00 61.96  ? 49  GLU D C   1 
ATOM   6704 O O   . GLU D 2 49  ? 128.463 143.330 166.545 1.00 61.96  ? 49  GLU D O   1 
ATOM   6705 C CB  . GLU D 2 49  ? 129.011 140.745 168.054 1.00 61.96  ? 49  GLU D CB  1 
ATOM   6706 C CG  . GLU D 2 49  ? 130.483 140.890 167.797 1.00 61.96  ? 49  GLU D CG  1 
ATOM   6707 C CD  . GLU D 2 49  ? 131.075 139.668 167.146 1.00 61.96  ? 49  GLU D CD  1 
ATOM   6708 O OE1 . GLU D 2 49  ? 132.313 139.607 167.004 1.00 61.96  ? 49  GLU D OE1 1 
ATOM   6709 O OE2 . GLU D 2 49  ? 130.305 138.764 166.778 1.00 61.96  ? 49  GLU D OE2 1 
ATOM   6710 N N   . TRP D 2 50  ? 129.351 142.024 164.950 1.00 65.10  ? 50  TRP D N   1 
ATOM   6711 C CA  . TRP D 2 50  ? 129.733 143.168 164.140 1.00 65.10  ? 50  TRP D CA  1 
ATOM   6712 C C   . TRP D 2 50  ? 128.505 143.907 163.632 1.00 65.10  ? 50  TRP D C   1 
ATOM   6713 O O   . TRP D 2 50  ? 128.470 145.140 163.630 1.00 65.10  ? 50  TRP D O   1 
ATOM   6714 C CB  . TRP D 2 50  ? 130.601 142.718 162.970 1.00 65.10  ? 50  TRP D CB  1 
ATOM   6715 C CG  . TRP D 2 50  ? 131.232 143.855 162.266 1.00 65.10  ? 50  TRP D CG  1 
ATOM   6716 C CD1 . TRP D 2 50  ? 132.388 144.478 162.601 1.00 65.10  ? 50  TRP D CD1 1 
ATOM   6717 C CD2 . TRP D 2 50  ? 130.728 144.536 161.118 1.00 65.10  ? 50  TRP D CD2 1 
ATOM   6718 N NE1 . TRP D 2 50  ? 132.646 145.497 161.728 1.00 65.10  ? 50  TRP D NE1 1 
ATOM   6719 C CE2 . TRP D 2 50  ? 131.638 145.555 160.807 1.00 65.10  ? 50  TRP D CE2 1 
ATOM   6720 C CE3 . TRP D 2 50  ? 129.596 144.382 160.322 1.00 65.10  ? 50  TRP D CE3 1 
ATOM   6721 C CZ2 . TRP D 2 50  ? 131.453 146.413 159.734 1.00 65.10  ? 50  TRP D CZ2 1 
ATOM   6722 C CZ3 . TRP D 2 50  ? 129.415 145.235 159.258 1.00 65.10  ? 50  TRP D CZ3 1 
ATOM   6723 C CH2 . TRP D 2 50  ? 130.337 146.236 158.973 1.00 65.10  ? 50  TRP D CH2 1 
ATOM   6724 N N   . PHE D 2 51  ? 127.487 143.164 163.198 1.00 60.28  ? 51  PHE D N   1 
ATOM   6725 C CA  . PHE D 2 51  ? 126.292 143.790 162.648 1.00 60.28  ? 51  PHE D CA  1 
ATOM   6726 C C   . PHE D 2 51  ? 125.392 144.350 163.734 1.00 60.28  ? 51  PHE D C   1 
ATOM   6727 O O   . PHE D 2 51  ? 124.817 145.425 163.562 1.00 60.28  ? 51  PHE D O   1 
ATOM   6728 C CB  . PHE D 2 51  ? 125.522 142.789 161.798 1.00 60.28  ? 51  PHE D CB  1 
ATOM   6729 C CG  . PHE D 2 51  ? 126.357 142.123 160.755 1.00 60.28  ? 51  PHE D CG  1 
ATOM   6730 C CD1 . PHE D 2 51  ? 126.462 142.664 159.496 1.00 60.28  ? 51  PHE D CD1 1 
ATOM   6731 C CD2 . PHE D 2 51  ? 127.035 140.962 161.032 1.00 60.28  ? 51  PHE D CD2 1 
ATOM   6732 C CE1 . PHE D 2 51  ? 127.224 142.060 158.539 1.00 60.28  ? 51  PHE D CE1 1 
ATOM   6733 C CE2 . PHE D 2 51  ? 127.799 140.358 160.075 1.00 60.28  ? 51  PHE D CE2 1 
ATOM   6734 C CZ  . PHE D 2 51  ? 127.893 140.907 158.829 1.00 60.28  ? 51  PHE D CZ  1 
ATOM   6735 N N   . HIS D 2 52  ? 125.263 143.655 164.854 1.00 60.93  ? 52  HIS D N   1 
ATOM   6736 C CA  . HIS D 2 52  ? 124.287 144.049 165.855 1.00 60.93  ? 52  HIS D CA  1 
ATOM   6737 C C   . HIS D 2 52  ? 124.856 144.984 166.908 1.00 60.93  ? 52  HIS D C   1 
ATOM   6738 O O   . HIS D 2 52  ? 124.207 145.971 167.269 1.00 60.93  ? 52  HIS D O   1 
ATOM   6739 C CB  . HIS D 2 52  ? 123.714 142.807 166.530 1.00 60.93  ? 52  HIS D CB  1 
ATOM   6740 C CG  . HIS D 2 52  ? 123.041 141.873 165.581 1.00 60.93  ? 52  HIS D CG  1 
ATOM   6741 N ND1 . HIS D 2 52  ? 122.146 142.303 164.629 1.00 60.93  ? 52  HIS D ND1 1 
ATOM   6742 C CD2 . HIS D 2 52  ? 123.138 140.535 165.430 1.00 60.93  ? 52  HIS D CD2 1 
ATOM   6743 C CE1 . HIS D 2 52  ? 121.716 141.268 163.934 1.00 60.93  ? 52  HIS D CE1 1 
ATOM   6744 N NE2 . HIS D 2 52  ? 122.304 140.183 164.399 1.00 60.93  ? 52  HIS D NE2 1 
ATOM   6745 N N   . CYS D 2 53  ? 126.053 144.702 167.412 1.00 66.02  ? 53  CYS D N   1 
ATOM   6746 C CA  . CYS D 2 53  ? 126.626 145.432 168.534 1.00 66.02  ? 53  CYS D CA  1 
ATOM   6747 C C   . CYS D 2 53  ? 127.596 146.493 168.041 1.00 66.02  ? 53  CYS D C   1 
ATOM   6748 O O   . CYS D 2 53  ? 128.383 146.244 167.127 1.00 66.02  ? 53  CYS D O   1 
ATOM   6749 C CB  . CYS D 2 53  ? 127.341 144.480 169.489 1.00 66.02  ? 53  CYS D CB  1 
ATOM   6750 S SG  . CYS D 2 53  ? 126.342 143.089 170.002 1.00 66.02  ? 53  CYS D SG  1 
ATOM   6751 N N   . THR D 2 54  ? 127.533 147.672 168.646 1.00 66.59  ? 54  THR D N   1 
ATOM   6752 C CA  . THR D 2 54  ? 128.474 148.742 168.350 1.00 66.59  ? 54  THR D CA  1 
ATOM   6753 C C   . THR D 2 54  ? 129.221 149.100 169.623 1.00 66.59  ? 54  THR D C   1 
ATOM   6754 O O   . THR D 2 54  ? 128.583 149.460 170.621 1.00 66.59  ? 54  THR D O   1 
ATOM   6755 C CB  . THR D 2 54  ? 127.752 149.968 167.802 1.00 66.59  ? 54  THR D CB  1 
ATOM   6756 O OG1 . THR D 2 54  ? 126.839 150.457 168.788 1.00 66.59  ? 54  THR D OG1 1 
ATOM   6757 C CG2 . THR D 2 54  ? 126.976 149.606 166.557 1.00 66.59  ? 54  THR D CG2 1 
ATOM   6758 N N   . PRO D 2 55  ? 130.549 149.018 169.647 1.00 64.30  ? 55  PRO D N   1 
ATOM   6759 C CA  . PRO D 2 55  ? 131.292 149.298 170.882 1.00 64.30  ? 55  PRO D CA  1 
ATOM   6760 C C   . PRO D 2 55  ? 131.221 150.774 171.233 1.00 64.30  ? 55  PRO D C   1 
ATOM   6761 O O   . PRO D 2 55  ? 131.379 151.637 170.370 1.00 64.30  ? 55  PRO D O   1 
ATOM   6762 C CB  . PRO D 2 55  ? 132.717 148.864 170.537 1.00 64.30  ? 55  PRO D CB  1 
ATOM   6763 C CG  . PRO D 2 55  ? 132.791 149.038 169.080 1.00 64.30  ? 55  PRO D CG  1 
ATOM   6764 C CD  . PRO D 2 55  ? 131.452 148.654 168.547 1.00 64.30  ? 55  PRO D CD  1 
ATOM   6765 N N   . ILE D 2 56  ? 130.978 151.058 172.504 1.00 66.67  ? 56  ILE D N   1 
ATOM   6766 C CA  . ILE D 2 56  ? 130.928 152.419 173.016 1.00 66.67  ? 56  ILE D CA  1 
ATOM   6767 C C   . ILE D 2 56  ? 132.054 152.578 174.020 1.00 66.67  ? 56  ILE D C   1 
ATOM   6768 O O   . ILE D 2 56  ? 131.977 152.046 175.131 1.00 66.67  ? 56  ILE D O   1 
ATOM   6769 C CB  . ILE D 2 56  ? 129.573 152.721 173.666 1.00 66.67  ? 56  ILE D CB  1 
ATOM   6770 C CG1 . ILE D 2 56  ? 128.456 152.595 172.641 1.00 66.67  ? 56  ILE D CG1 1 
ATOM   6771 C CG2 . ILE D 2 56  ? 129.576 154.100 174.264 1.00 66.67  ? 56  ILE D CG2 1 
ATOM   6772 C CD1 . ILE D 2 56  ? 128.593 153.544 171.492 1.00 66.67  ? 56  ILE D CD1 1 
ATOM   6773 N N   . LYS D 2 57  ? 133.093 153.316 173.650 1.00 70.02  ? 57  LYS D N   1 
ATOM   6774 C CA  . LYS D 2 57  ? 134.253 153.500 174.505 1.00 70.02  ? 57  LYS D CA  1 
ATOM   6775 C C   . LYS D 2 57  ? 134.250 154.911 175.069 1.00 70.02  ? 57  LYS D C   1 
ATOM   6776 O O   . LYS D 2 57  ? 134.131 155.884 174.322 1.00 70.02  ? 57  LYS D O   1 
ATOM   6777 C CB  . LYS D 2 57  ? 135.552 153.213 173.748 1.00 70.02  ? 57  LYS D CB  1 
ATOM   6778 C CG  . LYS D 2 57  ? 135.769 154.053 172.513 1.00 70.02  ? 57  LYS D CG  1 
ATOM   6779 C CD  . LYS D 2 57  ? 137.118 153.768 171.896 1.00 70.02  ? 57  LYS D CD  1 
ATOM   6780 C CE  . LYS D 2 57  ? 137.135 152.413 171.227 1.00 70.02  ? 57  LYS D CE  1 
ATOM   6781 N NZ  . LYS D 2 57  ? 138.422 152.172 170.524 1.00 70.02  ? 57  LYS D NZ  1 
ATOM   6782 N N   . GLU D 2 58  ? 134.357 155.012 176.386 1.00 77.65  ? 58  GLU D N   1 
ATOM   6783 C CA  . GLU D 2 58  ? 134.317 156.299 177.064 1.00 77.65  ? 58  GLU D CA  1 
ATOM   6784 C C   . GLU D 2 58  ? 135.594 156.445 177.876 1.00 77.65  ? 58  GLU D C   1 
ATOM   6785 O O   . GLU D 2 58  ? 135.698 155.864 178.966 1.00 77.65  ? 58  GLU D O   1 
ATOM   6786 C CB  . GLU D 2 58  ? 133.078 156.390 177.958 1.00 77.65  ? 58  GLU D CB  1 
ATOM   6787 C CG  . GLU D 2 58  ? 132.786 157.768 178.537 1.00 77.65  ? 58  GLU D CG  1 
ATOM   6788 C CD  . GLU D 2 58  ? 133.556 158.077 179.796 1.00 77.65  ? 58  GLU D CD  1 
ATOM   6789 O OE1 . GLU D 2 58  ? 133.887 157.133 180.538 1.00 77.65  ? 58  GLU D OE1 1 
ATOM   6790 O OE2 . GLU D 2 58  ? 133.826 159.270 180.047 1.00 77.65  ? 58  GLU D OE2 1 
ATOM   6791 N N   . PRO D 2 59  ? 136.597 157.170 177.384 1.00 76.76  ? 59  PRO D N   1 
ATOM   6792 C CA  . PRO D 2 59  ? 137.913 157.152 178.034 1.00 76.76  ? 59  PRO D CA  1 
ATOM   6793 C C   . PRO D 2 59  ? 137.876 157.737 179.435 1.00 76.76  ? 59  PRO D C   1 
ATOM   6794 O O   . PRO D 2 59  ? 137.173 158.711 179.700 1.00 76.76  ? 59  PRO D O   1 
ATOM   6795 C CB  . PRO D 2 59  ? 138.780 158.002 177.100 1.00 76.76  ? 59  PRO D CB  1 
ATOM   6796 C CG  . PRO D 2 59  ? 137.834 158.807 176.308 1.00 76.76  ? 59  PRO D CG  1 
ATOM   6797 C CD  . PRO D 2 59  ? 136.583 158.010 176.179 1.00 76.76  ? 59  PRO D CD  1 
ATOM   6798 N N   . GLN D 2 60  ? 138.648 157.128 180.328 1.00 79.96  ? 60  GLN D N   1 
ATOM   6799 C CA  . GLN D 2 60  ? 138.920 157.678 181.645 1.00 79.96  ? 60  GLN D CA  1 
ATOM   6800 C C   . GLN D 2 60  ? 140.171 158.547 181.563 1.00 79.96  ? 60  GLN D C   1 
ATOM   6801 O O   . GLN D 2 60  ? 140.618 158.930 180.480 1.00 79.96  ? 60  GLN D O   1 
ATOM   6802 C CB  . GLN D 2 60  ? 139.075 156.560 182.668 1.00 79.96  ? 60  GLN D CB  1 
ATOM   6803 C CG  . GLN D 2 60  ? 137.999 155.503 182.612 1.00 79.96  ? 60  GLN D CG  1 
ATOM   6804 C CD  . GLN D 2 60  ? 136.626 156.049 182.900 1.00 79.96  ? 60  GLN D CD  1 
ATOM   6805 O OE1 . GLN D 2 60  ? 136.202 156.109 184.050 1.00 79.96  ? 60  GLN D OE1 1 
ATOM   6806 N NE2 . GLN D 2 60  ? 135.914 156.441 181.854 1.00 79.96  ? 60  GLN D NE2 1 
ATOM   6807 N N   . SER D 2 61  ? 140.758 158.865 182.710 1.00 83.39  ? 61  SER D N   1 
ATOM   6808 C CA  . SER D 2 61  ? 141.954 159.700 182.754 1.00 83.39  ? 61  SER D CA  1 
ATOM   6809 C C   . SER D 2 61  ? 143.169 158.858 182.381 1.00 83.39  ? 61  SER D C   1 
ATOM   6810 O O   . SER D 2 61  ? 143.631 158.031 183.167 1.00 83.39  ? 61  SER D O   1 
ATOM   6811 C CB  . SER D 2 61  ? 142.119 160.316 184.137 1.00 83.39  ? 61  SER D CB  1 
ATOM   6812 O OG  . SER D 2 61  ? 142.372 159.316 185.105 1.00 83.39  ? 61  SER D OG  1 
ATOM   6813 N N   . GLY D 2 62  ? 143.693 159.070 181.179 1.00 81.83  ? 62  GLY D N   1 
ATOM   6814 C CA  . GLY D 2 62  ? 144.918 158.411 180.766 1.00 81.83  ? 62  GLY D CA  1 
ATOM   6815 C C   . GLY D 2 62  ? 144.743 157.487 179.582 1.00 81.83  ? 62  GLY D C   1 
ATOM   6816 O O   . GLY D 2 62  ? 143.956 157.772 178.676 1.00 81.83  ? 62  GLY D O   1 
ATOM   6817 N N   . SER D 2 63  ? 145.474 156.376 179.576 1.00 76.66  ? 63  SER D N   1 
ATOM   6818 C CA  . SER D 2 63  ? 145.310 155.337 178.571 1.00 76.66  ? 63  SER D CA  1 
ATOM   6819 C C   . SER D 2 63  ? 144.213 154.356 178.943 1.00 76.66  ? 63  SER D C   1 
ATOM   6820 O O   . SER D 2 63  ? 143.978 153.394 178.210 1.00 76.66  ? 63  SER D O   1 
ATOM   6821 C CB  . SER D 2 63  ? 146.624 154.590 178.362 1.00 76.66  ? 63  SER D CB  1 
ATOM   6822 O OG  . SER D 2 63  ? 147.057 154.003 179.571 1.00 76.66  ? 63  SER D OG  1 
ATOM   6823 N N   . VAL D 2 64  ? 143.543 154.582 180.063 1.00 73.43  ? 64  VAL D N   1 
ATOM   6824 C CA  . VAL D 2 64  ? 142.460 153.728 180.525 1.00 73.43  ? 64  VAL D CA  1 
ATOM   6825 C C   . VAL D 2 64  ? 141.160 154.203 179.904 1.00 73.43  ? 64  VAL D C   1 
ATOM   6826 O O   . VAL D 2 64  ? 140.850 155.398 179.936 1.00 73.43  ? 64  VAL D O   1 
ATOM   6827 C CB  . VAL D 2 64  ? 142.372 153.749 182.056 1.00 73.43  ? 64  VAL D CB  1 
ATOM   6828 C CG1 . VAL D 2 64  ? 141.305 152.805 182.535 1.00 73.43  ? 64  VAL D CG1 1 
ATOM   6829 C CG2 . VAL D 2 64  ? 143.704 153.389 182.647 1.00 73.43  ? 64  VAL D CG2 1 
ATOM   6830 N N   . ILE D 2 65  ? 140.400 153.275 179.335 1.00 68.81  ? 65  ILE D N   1 
ATOM   6831 C CA  . ILE D 2 65  ? 139.089 153.573 178.775 1.00 68.81  ? 65  ILE D CA  1 
ATOM   6832 C C   . ILE D 2 65  ? 138.085 152.592 179.355 1.00 68.81  ? 65  ILE D C   1 
ATOM   6833 O O   . ILE D 2 65  ? 138.463 151.615 180.008 1.00 68.81  ? 65  ILE D O   1 
ATOM   6834 C CB  . ILE D 2 65  ? 139.082 153.507 177.237 1.00 68.81  ? 65  ILE D CB  1 
ATOM   6835 C CG1 . ILE D 2 65  ? 138.954 152.071 176.767 1.00 68.81  ? 65  ILE D CG1 1 
ATOM   6836 C CG2 . ILE D 2 65  ? 140.337 154.107 176.668 1.00 68.81  ? 65  ILE D CG2 1 
ATOM   6837 C CD1 . ILE D 2 65  ? 138.832 151.952 175.285 1.00 68.81  ? 65  ILE D CD1 1 
ATOM   6838 N N   . LYS D 2 66  ? 136.807 152.868 179.142 1.00 68.72  ? 66  LYS D N   1 
ATOM   6839 C CA  . LYS D 2 66  ? 135.735 151.972 179.549 1.00 68.72  ? 66  LYS D CA  1 
ATOM   6840 C C   . LYS D 2 66  ? 134.998 151.505 178.305 1.00 68.72  ? 66  LYS D C   1 
ATOM   6841 O O   . LYS D 2 66  ? 134.677 152.316 177.433 1.00 68.72  ? 66  LYS D O   1 
ATOM   6842 C CB  . LYS D 2 66  ? 134.777 152.673 180.506 1.00 68.72  ? 66  LYS D CB  1 
ATOM   6843 C CG  . LYS D 2 66  ? 133.669 151.786 181.011 1.00 68.72  ? 66  LYS D CG  1 
ATOM   6844 C CD  . LYS D 2 66  ? 133.175 152.240 182.361 1.00 68.72  ? 66  LYS D CD  1 
ATOM   6845 C CE  . LYS D 2 66  ? 131.674 152.139 182.463 1.00 68.72  ? 66  LYS D CE  1 
ATOM   6846 N NZ  . LYS D 2 66  ? 131.234 152.113 183.881 1.00 68.72  ? 66  LYS D NZ  1 
ATOM   6847 N N   . LEU D 2 67  ? 134.740 150.210 178.215 1.00 65.42  ? 67  LEU D N   1 
ATOM   6848 C CA  . LEU D 2 67  ? 134.079 149.629 177.060 1.00 65.42  ? 67  LEU D CA  1 
ATOM   6849 C C   . LEU D 2 67  ? 132.737 149.024 177.434 1.00 65.42  ? 67  LEU D C   1 
ATOM   6850 O O   . LEU D 2 67  ? 132.540 148.545 178.552 1.00 65.42  ? 67  LEU D O   1 
ATOM   6851 C CB  . LEU D 2 67  ? 134.938 148.543 176.426 1.00 65.42  ? 67  LEU D CB  1 
ATOM   6852 C CG  . LEU D 2 67  ? 136.187 148.935 175.672 1.00 65.42  ? 67  LEU D CG  1 
ATOM   6853 C CD1 . LEU D 2 67  ? 137.070 147.733 175.569 1.00 65.42  ? 67  LEU D CD1 1 
ATOM   6854 C CD2 . LEU D 2 67  ? 135.780 149.393 174.300 1.00 65.42  ? 67  LEU D CD2 1 
ATOM   6855 N N   . TRP D 2 68  ? 131.821 149.044 176.477 1.00 68.35  ? 68  TRP D N   1 
ATOM   6856 C CA  . TRP D 2 68  ? 130.620 148.226 176.514 1.00 68.35  ? 68  TRP D CA  1 
ATOM   6857 C C   . TRP D 2 68  ? 130.056 148.183 175.104 1.00 68.35  ? 68  TRP D C   1 
ATOM   6858 O O   . TRP D 2 68  ? 130.649 148.721 174.165 1.00 68.35  ? 68  TRP D O   1 
ATOM   6859 C CB  . TRP D 2 68  ? 129.616 148.751 177.544 1.00 68.35  ? 68  TRP D CB  1 
ATOM   6860 C CG  . TRP D 2 68  ? 129.071 150.094 177.263 1.00 68.35  ? 68  TRP D CG  1 
ATOM   6861 C CD1 . TRP D 2 68  ? 128.063 150.406 176.410 1.00 68.35  ? 68  TRP D CD1 1 
ATOM   6862 C CD2 . TRP D 2 68  ? 129.484 151.319 177.863 1.00 68.35  ? 68  TRP D CD2 1 
ATOM   6863 N NE1 . TRP D 2 68  ? 127.828 151.755 176.428 1.00 68.35  ? 68  TRP D NE1 1 
ATOM   6864 C CE2 . TRP D 2 68  ? 128.692 152.337 177.315 1.00 68.35  ? 68  TRP D CE2 1 
ATOM   6865 C CE3 . TRP D 2 68  ? 130.453 151.654 178.806 1.00 68.35  ? 68  TRP D CE3 1 
ATOM   6866 C CZ2 . TRP D 2 68  ? 128.840 153.665 177.677 1.00 68.35  ? 68  TRP D CZ2 1 
ATOM   6867 C CZ3 . TRP D 2 68  ? 130.598 152.970 179.163 1.00 68.35  ? 68  TRP D CZ3 1 
ATOM   6868 C CH2 . TRP D 2 68  ? 129.797 153.961 178.601 1.00 68.35  ? 68  TRP D CH2 1 
ATOM   6869 N N   . ALA D 2 69  ? 128.914 147.527 174.946 1.00 69.78  ? 69  ALA D N   1 
ATOM   6870 C CA  . ALA D 2 69  ? 128.270 147.413 173.650 1.00 69.78  ? 69  ALA D CA  1 
ATOM   6871 C C   . ALA D 2 69  ? 126.828 147.863 173.770 1.00 69.78  ? 69  ALA D C   1 
ATOM   6872 O O   . ALA D 2 69  ? 126.201 147.708 174.817 1.00 69.78  ? 69  ALA D O   1 
ATOM   6873 C CB  . ALA D 2 69  ? 128.319 145.989 173.122 1.00 69.78  ? 69  ALA D CB  1 
ATOM   6874 N N   . ARG D 2 70  ? 126.304 148.436 172.692 1.00 72.21  ? 70  ARG D N   1 
ATOM   6875 C CA  . ARG D 2 70  ? 124.927 148.912 172.663 1.00 72.21  ? 70  ARG D CA  1 
ATOM   6876 C C   . ARG D 2 70  ? 124.283 148.532 171.337 1.00 72.21  ? 70  ARG D C   1 
ATOM   6877 O O   . ARG D 2 70  ? 124.680 149.027 170.282 1.00 72.21  ? 70  ARG D O   1 
ATOM   6878 C CB  . ARG D 2 70  ? 124.876 150.427 172.860 1.00 72.21  ? 70  ARG D CB  1 
ATOM   6879 C CG  . ARG D 2 70  ? 123.513 150.954 173.275 1.00 72.21  ? 70  ARG D CG  1 
ATOM   6880 C CD  . ARG D 2 70  ? 123.447 152.468 173.160 1.00 72.21  ? 70  ARG D CD  1 
ATOM   6881 N NE  . ARG D 2 70  ? 122.332 152.906 172.326 1.00 72.21  ? 70  ARG D NE  1 
ATOM   6882 C CZ  . ARG D 2 70  ? 122.470 153.487 171.138 1.00 72.21  ? 70  ARG D CZ  1 
ATOM   6883 N NH1 . ARG D 2 70  ? 123.681 153.703 170.640 1.00 72.21  ? 70  ARG D NH1 1 
ATOM   6884 N NH2 . ARG D 2 70  ? 121.399 153.853 170.447 1.00 72.21  ? 70  ARG D NH2 1 
ATOM   6885 N N   . GLY D 2 71  ? 123.290 147.651 171.391 1.00 69.71  ? 71  GLY D N   1 
ATOM   6886 C CA  . GLY D 2 71  ? 122.624 147.208 170.192 1.00 69.71  ? 71  GLY D CA  1 
ATOM   6887 C C   . GLY D 2 71  ? 121.183 146.881 170.470 1.00 69.71  ? 71  GLY D C   1 
ATOM   6888 O O   . GLY D 2 71  ? 120.607 147.320 171.465 1.00 69.71  ? 71  GLY D O   1 
ATOM   6889 N N   . GLY D 2 72  ? 120.590 146.105 169.573 1.00 70.28  ? 72  GLY D N   1 
ATOM   6890 C CA  . GLY D 2 72  ? 119.213 145.709 169.716 1.00 70.28  ? 72  GLY D CA  1 
ATOM   6891 C C   . GLY D 2 72  ? 119.078 144.460 170.556 1.00 70.28  ? 72  GLY D C   1 
ATOM   6892 O O   . GLY D 2 72  ? 119.988 144.087 171.295 1.00 70.28  ? 72  GLY D O   1 
ATOM   6893 N N   . PRO D 2 73  ? 117.932 143.783 170.463 1.00 69.43  ? 73  PRO D N   1 
ATOM   6894 C CA  . PRO D 2 73  ? 117.777 142.514 171.180 1.00 69.43  ? 73  PRO D CA  1 
ATOM   6895 C C   . PRO D 2 73  ? 118.722 141.445 170.695 1.00 69.43  ? 73  PRO D C   1 
ATOM   6896 O O   . PRO D 2 73  ? 118.893 140.435 171.384 1.00 69.43  ? 73  PRO D O   1 
ATOM   6897 C CB  . PRO D 2 73  ? 116.320 142.124 170.908 1.00 69.43  ? 73  PRO D CB  1 
ATOM   6898 C CG  . PRO D 2 73  ? 115.691 143.317 170.326 1.00 69.43  ? 73  PRO D CG  1 
ATOM   6899 C CD  . PRO D 2 73  ? 116.752 144.099 169.654 1.00 69.43  ? 73  PRO D CD  1 
ATOM   6900 N N   . SER D 2 74  ? 119.326 141.626 169.528 1.00 66.39  ? 74  SER D N   1 
ATOM   6901 C CA  . SER D 2 74  ? 120.284 140.678 168.990 1.00 66.39  ? 74  SER D CA  1 
ATOM   6902 C C   . SER D 2 74  ? 121.644 140.781 169.654 1.00 66.39  ? 74  SER D C   1 
ATOM   6903 O O   . SER D 2 74  ? 122.452 139.860 169.516 1.00 66.39  ? 74  SER D O   1 
ATOM   6904 C CB  . SER D 2 74  ? 120.421 140.896 167.490 1.00 66.39  ? 74  SER D CB  1 
ATOM   6905 O OG  . SER D 2 74  ? 119.187 140.663 166.842 1.00 66.39  ? 74  SER D OG  1 
ATOM   6906 N N   . CYS D 2 75  ? 121.916 141.873 170.364 1.00 67.95  ? 75  CYS D N   1 
ATOM   6907 C CA  . CYS D 2 75  ? 123.168 142.049 171.092 1.00 67.95  ? 75  CYS D CA  1 
ATOM   6908 C C   . CYS D 2 75  ? 122.975 141.501 172.500 1.00 67.95  ? 75  CYS D C   1 
ATOM   6909 O O   . CYS D 2 75  ? 122.814 142.236 173.469 1.00 67.95  ? 75  CYS D O   1 
ATOM   6910 C CB  . CYS D 2 75  ? 123.578 143.512 171.107 1.00 67.95  ? 75  CYS D CB  1 
ATOM   6911 S SG  . CYS D 2 75  ? 125.276 143.803 171.573 1.00 67.95  ? 75  CYS D SG  1 
ATOM   6912 N N   . ASP D 2 76  ? 122.974 140.178 172.598 1.00 63.21  ? 76  ASP D N   1 
ATOM   6913 C CA  . ASP D 2 76  ? 122.890 139.499 173.877 1.00 63.21  ? 76  ASP D CA  1 
ATOM   6914 C C   . ASP D 2 76  ? 124.240 139.538 174.578 1.00 63.21  ? 76  ASP D C   1 
ATOM   6915 O O   . ASP D 2 76  ? 125.213 140.088 174.067 1.00 63.21  ? 76  ASP D O   1 
ATOM   6916 C CB  . ASP D 2 76  ? 122.404 138.075 173.668 1.00 63.21  ? 76  ASP D CB  1 
ATOM   6917 C CG  . ASP D 2 76  ? 123.243 137.328 172.674 1.00 63.21  ? 76  ASP D CG  1 
ATOM   6918 O OD1 . ASP D 2 76  ? 124.138 137.954 172.081 1.00 63.21  ? 76  ASP D OD1 1 
ATOM   6919 O OD2 . ASP D 2 76  ? 123.015 136.120 172.483 1.00 63.21  ? 76  ASP D OD2 1 
ATOM   6920 N N   . LYS D 2 77  ? 124.313 138.929 175.763 1.00 59.26  ? 77  LYS D N   1 
ATOM   6921 C CA  . LYS D 2 77  ? 125.537 139.008 176.553 1.00 59.26  ? 77  LYS D CA  1 
ATOM   6922 C C   . LYS D 2 77  ? 126.726 138.408 175.823 1.00 59.26  ? 77  LYS D C   1 
ATOM   6923 O O   . LYS D 2 77  ? 127.858 138.865 176.008 1.00 59.26  ? 77  LYS D O   1 
ATOM   6924 C CB  . LYS D 2 77  ? 125.346 138.322 177.895 1.00 59.26  ? 77  LYS D CB  1 
ATOM   6925 C CG  . LYS D 2 77  ? 124.615 139.172 178.881 1.00 59.26  ? 77  LYS D CG  1 
ATOM   6926 C CD  . LYS D 2 77  ? 124.385 138.433 180.159 1.00 59.26  ? 77  LYS D CD  1 
ATOM   6927 C CE  . LYS D 2 77  ? 124.457 139.365 181.332 1.00 59.26  ? 77  LYS D CE  1 
ATOM   6928 N NZ  . LYS D 2 77  ? 124.625 138.608 182.592 1.00 59.26  ? 77  LYS D NZ  1 
ATOM   6929 N N   . ARG D 2 78  ? 126.503 137.399 174.990 1.00 57.67  ? 78  ARG D N   1 
ATOM   6930 C CA  . ARG D 2 78  ? 127.606 136.839 174.222 1.00 57.67  ? 78  ARG D CA  1 
ATOM   6931 C C   . ARG D 2 78  ? 128.141 137.843 173.215 1.00 57.67  ? 78  ARG D C   1 
ATOM   6932 O O   . ARG D 2 78  ? 129.353 137.957 173.028 1.00 57.67  ? 78  ARG D O   1 
ATOM   6933 C CB  . ARG D 2 78  ? 127.157 135.564 173.522 1.00 57.67  ? 78  ARG D CB  1 
ATOM   6934 C CG  . ARG D 2 78  ? 128.166 135.014 172.565 1.00 57.67  ? 78  ARG D CG  1 
ATOM   6935 C CD  . ARG D 2 78  ? 127.783 133.625 172.159 1.00 57.67  ? 78  ARG D CD  1 
ATOM   6936 N NE  . ARG D 2 78  ? 126.818 133.642 171.073 1.00 57.67  ? 78  ARG D NE  1 
ATOM   6937 C CZ  . ARG D 2 78  ? 126.759 132.720 170.125 1.00 57.67  ? 78  ARG D CZ  1 
ATOM   6938 N NH1 . ARG D 2 78  ? 127.599 131.701 170.145 1.00 57.67  ? 78  ARG D NH1 1 
ATOM   6939 N NH2 . ARG D 2 78  ? 125.848 132.806 169.172 1.00 57.67  ? 78  ARG D NH2 1 
ATOM   6940 N N   . GLY D 2 79  ? 127.255 138.580 172.556 1.00 56.88  ? 79  GLY D N   1 
ATOM   6941 C CA  . GLY D 2 79  ? 127.710 139.589 171.616 1.00 56.88  ? 79  GLY D CA  1 
ATOM   6942 C C   . GLY D 2 79  ? 128.462 140.711 172.294 1.00 56.88  ? 79  GLY D C   1 
ATOM   6943 O O   . GLY D 2 79  ? 129.478 141.187 171.784 1.00 56.88  ? 79  GLY D O   1 
ATOM   6944 N N   . GLU D 2 80  ? 127.979 141.146 173.456 1.00 60.41  ? 80  GLU D N   1 
ATOM   6945 C CA  . GLU D 2 80  ? 128.694 142.162 174.214 1.00 60.41  ? 80  GLU D CA  1 
ATOM   6946 C C   . GLU D 2 80  ? 130.075 141.678 174.612 1.00 60.41  ? 80  GLU D C   1 
ATOM   6947 O O   . GLU D 2 80  ? 131.062 142.400 174.448 1.00 60.41  ? 80  GLU D O   1 
ATOM   6948 C CB  . GLU D 2 80  ? 127.898 142.549 175.454 1.00 60.41  ? 80  GLU D CB  1 
ATOM   6949 C CG  . GLU D 2 80  ? 126.427 142.702 175.222 1.00 60.41  ? 80  GLU D CG  1 
ATOM   6950 C CD  . GLU D 2 80  ? 125.728 143.299 176.413 1.00 60.41  ? 80  GLU D CD  1 
ATOM   6951 O OE1 . GLU D 2 80  ? 126.383 143.458 177.455 1.00 60.41  ? 80  GLU D OE1 1 
ATOM   6952 O OE2 . GLU D 2 80  ? 124.522 143.596 176.320 1.00 60.41  ? 80  GLU D OE2 1 
ATOM   6953 N N   . TYR D 2 81  ? 130.170 140.456 175.131 1.00 55.46  ? 81  TYR D N   1 
ATOM   6954 C CA  . TYR D 2 81  ? 131.471 139.928 175.517 1.00 55.46  ? 81  TYR D CA  1 
ATOM   6955 C C   . TYR D 2 81  ? 132.407 139.834 174.324 1.00 55.46  ? 81  TYR D C   1 
ATOM   6956 O O   . TYR D 2 81  ? 133.576 140.221 174.415 1.00 55.46  ? 81  TYR D O   1 
ATOM   6957 C CB  . TYR D 2 81  ? 131.307 138.562 176.165 1.00 55.46  ? 81  TYR D CB  1 
ATOM   6958 C CG  . TYR D 2 81  ? 132.519 138.091 176.910 1.00 55.46  ? 81  TYR D CG  1 
ATOM   6959 C CD1 . TYR D 2 81  ? 133.489 137.337 176.285 1.00 55.46  ? 81  TYR D CD1 1 
ATOM   6960 C CD2 . TYR D 2 81  ? 132.690 138.391 178.242 1.00 55.46  ? 81  TYR D CD2 1 
ATOM   6961 C CE1 . TYR D 2 81  ? 134.592 136.902 176.967 1.00 55.46  ? 81  TYR D CE1 1 
ATOM   6962 C CE2 . TYR D 2 81  ? 133.789 137.959 178.929 1.00 55.46  ? 81  TYR D CE2 1 
ATOM   6963 C CZ  . TYR D 2 81  ? 134.737 137.217 178.289 1.00 55.46  ? 81  TYR D CZ  1 
ATOM   6964 O OH  . TYR D 2 81  ? 135.840 136.788 178.982 1.00 55.46  ? 81  TYR D OH  1 
ATOM   6965 N N   . LYS D 2 82  ? 131.920 139.324 173.196 1.00 52.27  ? 82  LYS D N   1 
ATOM   6966 C CA  . LYS D 2 82  ? 132.783 139.189 172.032 1.00 52.27  ? 82  LYS D CA  1 
ATOM   6967 C C   . LYS D 2 82  ? 133.275 140.538 171.544 1.00 52.27  ? 82  LYS D C   1 
ATOM   6968 O O   . LYS D 2 82  ? 134.452 140.688 171.212 1.00 52.27  ? 82  LYS D O   1 
ATOM   6969 C CB  . LYS D 2 82  ? 132.059 138.461 170.910 1.00 52.27  ? 82  LYS D CB  1 
ATOM   6970 C CG  . LYS D 2 82  ? 131.807 137.010 171.174 1.00 52.27  ? 82  LYS D CG  1 
ATOM   6971 C CD  . LYS D 2 82  ? 131.913 136.228 169.893 1.00 52.27  ? 82  LYS D CD  1 
ATOM   6972 C CE  . LYS D 2 82  ? 130.879 136.677 168.904 1.00 52.27  ? 82  LYS D CE  1 
ATOM   6973 N NZ  . LYS D 2 82  ? 130.899 135.834 167.689 1.00 52.27  ? 82  LYS D NZ  1 
ATOM   6974 N N   . THR D 2 83  ? 132.396 141.537 171.488 1.00 53.09  ? 83  THR D N   1 
ATOM   6975 C CA  . THR D 2 83  ? 132.832 142.820 170.956 1.00 53.09  ? 83  THR D CA  1 
ATOM   6976 C C   . THR D 2 83  ? 133.772 143.526 171.923 1.00 53.09  ? 83  THR D C   1 
ATOM   6977 O O   . THR D 2 83  ? 134.728 144.185 171.497 1.00 53.09  ? 83  THR D O   1 
ATOM   6978 C CB  . THR D 2 83  ? 131.630 143.693 170.610 1.00 53.09  ? 83  THR D CB  1 
ATOM   6979 O OG1 . THR D 2 83  ? 132.052 144.760 169.759 1.00 53.09  ? 83  THR D OG1 1 
ATOM   6980 C CG2 . THR D 2 83  ? 131.026 144.282 171.832 1.00 53.09  ? 83  THR D CG2 1 
ATOM   6981 N N   . ILE D 2 84  ? 133.555 143.364 173.227 1.00 52.82  ? 84  ILE D N   1 
ATOM   6982 C CA  . ILE D 2 84  ? 134.471 143.942 174.200 1.00 52.82  ? 84  ILE D CA  1 
ATOM   6983 C C   . ILE D 2 84  ? 135.847 143.313 174.076 1.00 52.82  ? 84  ILE D C   1 
ATOM   6984 O O   . ILE D 2 84  ? 136.864 144.013 174.047 1.00 52.82  ? 84  ILE D O   1 
ATOM   6985 C CB  . ILE D 2 84  ? 133.909 143.784 175.619 1.00 52.82  ? 84  ILE D CB  1 
ATOM   6986 C CG1 . ILE D 2 84  ? 132.722 144.714 175.833 1.00 52.82  ? 84  ILE D CG1 1 
ATOM   6987 C CG2 . ILE D 2 84  ? 134.978 143.993 176.627 1.00 52.82  ? 84  ILE D CG2 1 
ATOM   6988 C CD1 . ILE D 2 84  ? 131.995 144.448 177.105 1.00 52.82  ? 84  ILE D CD1 1 
ATOM   6989 N N   . VAL D 2 85  ? 135.905 141.984 174.011 1.00 53.12  ? 85  VAL D N   1 
ATOM   6990 C CA  . VAL D 2 85  ? 137.193 141.312 173.879 1.00 53.12  ? 85  VAL D CA  1 
ATOM   6991 C C   . VAL D 2 85  ? 137.884 141.731 172.593 1.00 53.12  ? 85  VAL D C   1 
ATOM   6992 O O   . VAL D 2 85  ? 139.102 141.934 172.564 1.00 53.12  ? 85  VAL D O   1 
ATOM   6993 C CB  . VAL D 2 85  ? 137.013 139.791 173.953 1.00 53.12  ? 85  VAL D CB  1 
ATOM   6994 C CG1 . VAL D 2 85  ? 138.284 139.103 173.560 1.00 53.12  ? 85  VAL D CG1 1 
ATOM   6995 C CG2 . VAL D 2 85  ? 136.637 139.403 175.343 1.00 53.12  ? 85  VAL D CG2 1 
ATOM   6996 N N   . LYS D 2 86  ? 137.128 141.856 171.507 1.00 56.28  ? 86  LYS D N   1 
ATOM   6997 C CA  . LYS D 2 86  ? 137.732 142.271 170.251 1.00 56.28  ? 86  LYS D CA  1 
ATOM   6998 C C   . LYS D 2 86  ? 138.353 143.650 170.383 1.00 56.28  ? 86  LYS D C   1 
ATOM   6999 O O   . LYS D 2 86  ? 139.488 143.872 169.954 1.00 56.28  ? 86  LYS D O   1 
ATOM   7000 C CB  . LYS D 2 86  ? 136.682 142.258 169.150 1.00 56.28  ? 86  LYS D CB  1 
ATOM   7001 C CG  . LYS D 2 86  ? 137.244 142.263 167.769 1.00 56.28  ? 86  LYS D CG  1 
ATOM   7002 C CD  . LYS D 2 86  ? 136.430 141.361 166.874 1.00 56.28  ? 86  LYS D CD  1 
ATOM   7003 C CE  . LYS D 2 86  ? 134.978 141.794 166.835 1.00 56.28  ? 86  LYS D CE  1 
ATOM   7004 N NZ  . LYS D 2 86  ? 134.836 143.236 166.512 1.00 56.28  ? 86  LYS D NZ  1 
ATOM   7005 N N   . ARG D 2 87  ? 137.632 144.588 170.996 1.00 59.38  ? 87  ARG D N   1 
ATOM   7006 C CA  . ARG D 2 87  ? 138.190 145.924 171.169 1.00 59.38  ? 87  ARG D CA  1 
ATOM   7007 C C   . ARG D 2 87  ? 139.440 145.890 172.032 1.00 59.38  ? 87  ARG D C   1 
ATOM   7008 O O   . ARG D 2 87  ? 140.435 146.555 171.725 1.00 59.38  ? 87  ARG D O   1 
ATOM   7009 C CB  . ARG D 2 87  ? 137.151 146.857 171.780 1.00 59.38  ? 87  ARG D CB  1 
ATOM   7010 C CG  . ARG D 2 87  ? 136.098 147.328 170.815 1.00 59.38  ? 87  ARG D CG  1 
ATOM   7011 C CD  . ARG D 2 87  ? 136.717 148.102 169.687 1.00 59.38  ? 87  ARG D CD  1 
ATOM   7012 N NE  . ARG D 2 87  ? 136.812 147.299 168.478 1.00 59.38  ? 87  ARG D NE  1 
ATOM   7013 C CZ  . ARG D 2 87  ? 137.689 147.526 167.513 1.00 59.38  ? 87  ARG D CZ  1 
ATOM   7014 N NH1 . ARG D 2 87  ? 138.544 148.529 167.624 1.00 59.38  ? 87  ARG D NH1 1 
ATOM   7015 N NH2 . ARG D 2 87  ? 137.712 146.754 166.442 1.00 59.38  ? 87  ARG D NH2 1 
ATOM   7016 N N   . ILE D 2 88  ? 139.412 145.111 173.112 1.00 57.13  ? 88  ILE D N   1 
ATOM   7017 C CA  . ILE D 2 88  ? 140.547 145.060 174.028 1.00 57.13  ? 88  ILE D CA  1 
ATOM   7018 C C   . ILE D 2 88  ? 141.776 144.505 173.333 1.00 57.13  ? 88  ILE D C   1 
ATOM   7019 O O   . ILE D 2 88  ? 142.878 145.044 173.467 1.00 57.13  ? 88  ILE D O   1 
ATOM   7020 C CB  . ILE D 2 88  ? 140.191 144.228 175.268 1.00 57.13  ? 88  ILE D CB  1 
ATOM   7021 C CG1 . ILE D 2 88  ? 139.357 145.048 176.238 1.00 57.13  ? 88  ILE D CG1 1 
ATOM   7022 C CG2 . ILE D 2 88  ? 141.439 143.742 175.943 1.00 57.13  ? 88  ILE D CG2 1 
ATOM   7023 C CD1 . ILE D 2 88  ? 138.975 144.290 177.472 1.00 57.13  ? 88  ILE D CD1 1 
ATOM   7024 N N   . THR D 2 89  ? 141.621 143.421 172.588 1.00 56.66  ? 89  THR D N   1 
ATOM   7025 C CA  . THR D 2 89  ? 142.775 142.794 171.965 1.00 56.66  ? 89  THR D CA  1 
ATOM   7026 C C   . THR D 2 89  ? 143.118 143.382 170.610 1.00 56.66  ? 89  THR D C   1 
ATOM   7027 O O   . THR D 2 89  ? 144.071 142.919 169.980 1.00 56.66  ? 89  THR D O   1 
ATOM   7028 C CB  . THR D 2 89  ? 142.553 141.294 171.801 1.00 56.66  ? 89  THR D CB  1 
ATOM   7029 O OG1 . THR D 2 89  ? 141.567 141.073 170.792 1.00 56.66  ? 89  THR D OG1 1 
ATOM   7030 C CG2 . THR D 2 89  ? 142.088 140.684 173.097 1.00 56.66  ? 89  THR D CG2 1 
ATOM   7031 N N   . ARG D 2 90  ? 142.369 144.368 170.129 1.00 59.32  ? 90  ARG D N   1 
ATOM   7032 C CA  . ARG D 2 90  ? 142.667 144.940 168.832 1.00 59.32  ? 90  ARG D CA  1 
ATOM   7033 C C   . ARG D 2 90  ? 143.057 146.407 168.872 1.00 59.32  ? 90  ARG D C   1 
ATOM   7034 O O   . ARG D 2 90  ? 143.737 146.867 167.953 1.00 59.32  ? 90  ARG D O   1 
ATOM   7035 C CB  . ARG D 2 90  ? 141.462 144.766 167.906 1.00 59.32  ? 90  ARG D CB  1 
ATOM   7036 C CG  . ARG D 2 90  ? 141.797 144.728 166.456 1.00 59.32  ? 90  ARG D CG  1 
ATOM   7037 C CD  . ARG D 2 90  ? 140.631 144.197 165.677 1.00 59.32  ? 90  ARG D CD  1 
ATOM   7038 N NE  . ARG D 2 90  ? 140.451 142.775 165.914 1.00 59.32  ? 90  ARG D NE  1 
ATOM   7039 C CZ  . ARG D 2 90  ? 139.696 141.994 165.157 1.00 59.32  ? 90  ARG D CZ  1 
ATOM   7040 N NH1 . ARG D 2 90  ? 139.046 142.506 164.127 1.00 59.32  ? 90  ARG D NH1 1 
ATOM   7041 N NH2 . ARG D 2 90  ? 139.584 140.708 165.436 1.00 59.32  ? 90  ARG D NH2 1 
ATOM   7042 N N   . ASP D 2 91  ? 142.650 147.155 169.894 1.00 68.51  ? 91  ASP D N   1 
ATOM   7043 C CA  . ASP D 2 91  ? 143.042 148.551 170.012 1.00 68.51  ? 91  ASP D CA  1 
ATOM   7044 C C   . ASP D 2 91  ? 144.280 148.762 170.866 1.00 68.51  ? 91  ASP D C   1 
ATOM   7045 O O   . ASP D 2 91  ? 144.762 149.894 170.956 1.00 68.51  ? 91  ASP D O   1 
ATOM   7046 C CB  . ASP D 2 91  ? 141.895 149.382 170.589 1.00 68.51  ? 91  ASP D CB  1 
ATOM   7047 C CG  . ASP D 2 91  ? 140.781 149.599 169.596 1.00 68.51  ? 91  ASP D CG  1 
ATOM   7048 O OD1 . ASP D 2 91  ? 140.926 149.154 168.440 1.00 68.51  ? 91  ASP D OD1 1 
ATOM   7049 O OD2 . ASP D 2 91  ? 139.764 150.224 169.965 1.00 68.51  ? 91  ASP D OD2 1 
ATOM   7050 N N   . TYR D 2 92  ? 144.801 147.717 171.491 1.00 69.61  ? 92  TYR D N   1 
ATOM   7051 C CA  . TYR D 2 92  ? 145.935 147.824 172.394 1.00 69.61  ? 92  TYR D CA  1 
ATOM   7052 C C   . TYR D 2 92  ? 147.015 146.851 171.959 1.00 69.61  ? 92  TYR D C   1 
ATOM   7053 O O   . TYR D 2 92  ? 146.728 145.680 171.701 1.00 69.61  ? 92  TYR D O   1 
ATOM   7054 C CB  . TYR D 2 92  ? 145.504 147.544 173.826 1.00 69.61  ? 92  TYR D CB  1 
ATOM   7055 C CG  . TYR D 2 92  ? 144.696 148.660 174.425 1.00 69.61  ? 92  TYR D CG  1 
ATOM   7056 C CD1 . TYR D 2 92  ? 145.245 149.503 175.364 1.00 69.61  ? 92  TYR D CD1 1 
ATOM   7057 C CD2 . TYR D 2 92  ? 143.393 148.883 174.035 1.00 69.61  ? 92  TYR D CD2 1 
ATOM   7058 C CE1 . TYR D 2 92  ? 144.526 150.522 175.906 1.00 69.61  ? 92  TYR D CE1 1 
ATOM   7059 C CE2 . TYR D 2 92  ? 142.668 149.904 174.570 1.00 69.61  ? 92  TYR D CE2 1 
ATOM   7060 C CZ  . TYR D 2 92  ? 143.242 150.721 175.505 1.00 69.61  ? 92  TYR D CZ  1 
ATOM   7061 O OH  . TYR D 2 92  ? 142.525 151.749 176.052 1.00 69.61  ? 92  TYR D OH  1 
ATOM   7062 N N   . GLU D 2 93  ? 148.252 147.333 171.880 1.00 78.95  ? 93  GLU D N   1 
ATOM   7063 C CA  . GLU D 2 93  ? 149.346 146.505 171.405 1.00 78.95  ? 93  GLU D CA  1 
ATOM   7064 C C   . GLU D 2 93  ? 150.188 146.052 172.583 1.00 78.95  ? 93  GLU D C   1 
ATOM   7065 O O   . GLU D 2 93  ? 150.891 146.875 173.179 1.00 78.95  ? 93  GLU D O   1 
ATOM   7066 C CB  . GLU D 2 93  ? 150.202 147.275 170.408 1.00 78.95  ? 93  GLU D CB  1 
ATOM   7067 C CG  . GLU D 2 93  ? 151.349 146.472 169.825 1.00 78.95  ? 93  GLU D CG  1 
ATOM   7068 C CD  . GLU D 2 93  ? 150.892 145.305 168.972 1.00 78.95  ? 93  GLU D CD  1 
ATOM   7069 O OE1 . GLU D 2 93  ? 149.773 145.366 168.422 1.00 78.95  ? 93  GLU D OE1 1 
ATOM   7070 O OE2 . GLU D 2 93  ? 151.656 144.328 168.845 1.00 78.95  ? 93  GLU D OE2 1 
ATOM   7071 N N   . PRO D 2 94  ? 150.165 144.771 172.950 1.00 75.60  ? 94  PRO D N   1 
ATOM   7072 C CA  . PRO D 2 94  ? 150.952 144.307 174.095 1.00 75.60  ? 94  PRO D CA  1 
ATOM   7073 C C   . PRO D 2 94  ? 152.420 144.074 173.791 1.00 75.60  ? 94  PRO D C   1 
ATOM   7074 O O   . PRO D 2 94  ? 153.183 143.779 174.715 1.00 75.60  ? 94  PRO D O   1 
ATOM   7075 C CB  . PRO D 2 94  ? 150.262 142.992 174.460 1.00 75.60  ? 94  PRO D CB  1 
ATOM   7076 C CG  . PRO D 2 94  ? 149.754 142.491 173.185 1.00 75.60  ? 94  PRO D CG  1 
ATOM   7077 C CD  . PRO D 2 94  ? 149.387 143.683 172.347 1.00 75.60  ? 94  PRO D CD  1 
ATOM   7078 N N   . ASN D 2 95  ? 152.834 144.165 172.531 1.00 81.10  ? 95  ASN D N   1 
ATOM   7079 C CA  . ASN D 2 95  ? 154.245 144.104 172.185 1.00 81.10  ? 95  ASN D CA  1 
ATOM   7080 C C   . ASN D 2 95  ? 154.939 145.444 172.358 1.00 81.10  ? 95  ASN D C   1 
ATOM   7081 O O   . ASN D 2 95  ? 156.170 145.492 172.363 1.00 81.10  ? 95  ASN D O   1 
ATOM   7082 C CB  . ASN D 2 95  ? 154.418 143.616 170.748 1.00 81.10  ? 95  ASN D CB  1 
ATOM   7083 C CG  . ASN D 2 95  ? 153.676 142.332 170.477 1.00 81.10  ? 95  ASN D CG  1 
ATOM   7084 O OD1 . ASN D 2 95  ? 154.141 141.248 170.818 1.00 81.10  ? 95  ASN D OD1 1 
ATOM   7085 N ND2 . ASN D 2 95  ? 152.518 142.444 169.853 1.00 81.10  ? 95  ASN D ND2 1 
ATOM   7086 N N   . ASP D 2 96  ? 154.181 146.526 172.501 1.00 83.44  ? 96  ASP D N   1 
ATOM   7087 C CA  . ASP D 2 96  ? 154.754 147.829 172.798 1.00 83.44  ? 96  ASP D CA  1 
ATOM   7088 C C   . ASP D 2 96  ? 154.926 147.969 174.300 1.00 83.44  ? 96  ASP D C   1 
ATOM   7089 O O   . ASP D 2 96  ? 156.031 148.226 174.785 1.00 83.44  ? 96  ASP D O   1 
ATOM   7090 C CB  . ASP D 2 96  ? 153.866 148.934 172.241 1.00 83.44  ? 96  ASP D CB  1 
ATOM   7091 C CG  . ASP D 2 96  ? 153.732 148.852 170.745 1.00 83.44  ? 96  ASP D CG  1 
ATOM   7092 O OD1 . ASP D 2 96  ? 154.186 147.842 170.171 1.00 83.44  ? 96  ASP D OD1 1 
ATOM   7093 O OD2 . ASP D 2 96  ? 153.171 149.789 170.141 1.00 83.44  ? 96  ASP D OD2 1 
ATOM   7094 N N   . GLU D 2 97  ? 153.838 147.805 175.042 1.00 80.05  ? 97  GLU D N   1 
ATOM   7095 C CA  . GLU D 2 97  ? 153.906 147.596 176.477 1.00 80.05  ? 97  GLU D CA  1 
ATOM   7096 C C   . GLU D 2 97  ? 152.700 146.789 176.925 1.00 80.05  ? 97  GLU D C   1 
ATOM   7097 O O   . GLU D 2 97  ? 151.687 146.706 176.233 1.00 80.05  ? 97  GLU D O   1 
ATOM   7098 C CB  . GLU D 2 97  ? 153.996 148.907 177.256 1.00 80.05  ? 97  GLU D CB  1 
ATOM   7099 C CG  . GLU D 2 97  ? 152.802 149.806 177.176 1.00 80.05  ? 97  GLU D CG  1 
ATOM   7100 C CD  . GLU D 2 97  ? 153.047 151.085 177.935 1.00 80.05  ? 97  GLU D CD  1 
ATOM   7101 O OE1 . GLU D 2 97  ? 154.158 151.225 178.480 1.00 80.05  ? 97  GLU D OE1 1 
ATOM   7102 O OE2 . GLU D 2 97  ? 152.153 151.949 177.997 1.00 80.05  ? 97  GLU D OE2 1 
ATOM   7103 N N   . HIS D 2 98  ? 152.834 146.180 178.093 1.00 75.47  ? 98  HIS D N   1 
ATOM   7104 C CA  . HIS D 2 98  ? 151.873 145.188 178.543 1.00 75.47  ? 98  HIS D CA  1 
ATOM   7105 C C   . HIS D 2 98  ? 150.648 145.873 179.120 1.00 75.47  ? 98  HIS D C   1 
ATOM   7106 O O   . HIS D 2 98  ? 150.766 146.779 179.948 1.00 75.47  ? 98  HIS D O   1 
ATOM   7107 C CB  . HIS D 2 98  ? 152.516 144.267 179.571 1.00 75.47  ? 98  HIS D CB  1 
ATOM   7108 C CG  . HIS D 2 98  ? 153.621 143.436 179.010 1.00 75.47  ? 98  HIS D CG  1 
ATOM   7109 N ND1 . HIS D 2 98  ? 153.540 142.838 177.772 1.00 75.47  ? 98  HIS D ND1 1 
ATOM   7110 C CD2 . HIS D 2 98  ? 154.832 143.105 179.513 1.00 75.47  ? 98  HIS D CD2 1 
ATOM   7111 C CE1 . HIS D 2 98  ? 154.655 142.172 177.536 1.00 75.47  ? 98  HIS D CE1 1 
ATOM   7112 N NE2 . HIS D 2 98  ? 155.455 142.318 178.577 1.00 75.47  ? 98  HIS D NE2 1 
ATOM   7113 N N   . LEU D 2 99  ? 149.476 145.440 178.680 1.00 68.65  ? 99  LEU D N   1 
ATOM   7114 C CA  . LEU D 2 99  ? 148.233 145.996 179.168 1.00 68.65  ? 99  LEU D CA  1 
ATOM   7115 C C   . LEU D 2 99  ? 147.611 145.092 180.219 1.00 68.65  ? 99  LEU D C   1 
ATOM   7116 O O   . LEU D 2 99  ? 148.083 143.989 180.488 1.00 68.65  ? 99  LEU D O   1 
ATOM   7117 C CB  . LEU D 2 99  ? 147.247 146.213 178.027 1.00 68.65  ? 99  LEU D CB  1 
ATOM   7118 C CG  . LEU D 2 99  ? 146.582 145.016 177.382 1.00 68.65  ? 99  LEU D CG  1 
ATOM   7119 C CD1 . LEU D 2 99  ? 145.416 145.482 176.594 1.00 68.65  ? 99  LEU D CD1 1 
ATOM   7120 C CD2 . LEU D 2 99  ? 147.560 144.407 176.439 1.00 68.65  ? 99  LEU D CD2 1 
ATOM   7121 N N   . SER D 2 100 ? 146.536 145.587 180.823 1.00 70.24  ? 100 SER D N   1 
ATOM   7122 C CA  . SER D 2 100 ? 145.807 144.846 181.840 1.00 70.24  ? 100 SER D CA  1 
ATOM   7123 C C   . SER D 2 100 ? 144.376 145.346 181.849 1.00 70.24  ? 100 SER D C   1 
ATOM   7124 O O   . SER D 2 100 ? 144.150 146.555 181.912 1.00 70.24  ? 100 SER D O   1 
ATOM   7125 C CB  . SER D 2 100 ? 146.437 145.026 183.214 1.00 70.24  ? 100 SER D CB  1 
ATOM   7126 O OG  . SER D 2 100 ? 146.239 146.345 183.674 1.00 70.24  ? 100 SER D OG  1 
ATOM   7127 N N   . PHE D 2 101 ? 143.419 144.428 181.799 1.00 68.77  ? 101 PHE D N   1 
ATOM   7128 C CA  . PHE D 2 101 ? 142.013 144.779 181.723 1.00 68.77  ? 101 PHE D CA  1 
ATOM   7129 C C   . PHE D 2 101 ? 141.224 144.000 182.761 1.00 68.77  ? 101 PHE D C   1 
ATOM   7130 O O   . PHE D 2 101 ? 141.774 143.211 183.529 1.00 68.77  ? 101 PHE D O   1 
ATOM   7131 C CB  . PHE D 2 101 ? 141.444 144.502 180.335 1.00 68.77  ? 101 PHE D CB  1 
ATOM   7132 C CG  . PHE D 2 101 ? 141.489 143.065 179.948 1.00 68.77  ? 101 PHE D CG  1 
ATOM   7133 C CD1 . PHE D 2 101 ? 142.653 142.499 179.484 1.00 68.77  ? 101 PHE D CD1 1 
ATOM   7134 C CD2 . PHE D 2 101 ? 140.375 142.272 180.064 1.00 68.77  ? 101 PHE D CD2 1 
ATOM   7135 C CE1 . PHE D 2 101 ? 142.697 141.178 179.141 1.00 68.77  ? 101 PHE D CE1 1 
ATOM   7136 C CE2 . PHE D 2 101 ? 140.424 140.951 179.719 1.00 68.77  ? 101 PHE D CE2 1 
ATOM   7137 C CZ  . PHE D 2 101 ? 141.583 140.406 179.258 1.00 68.77  ? 101 PHE D CZ  1 
ATOM   7138 N N   . CYS D 2 102 ? 139.921 144.240 182.776 1.00 74.05  ? 102 CYS D N   1 
ATOM   7139 C CA  . CYS D 2 102 ? 138.985 143.500 183.607 1.00 74.05  ? 102 CYS D CA  1 
ATOM   7140 C C   . CYS D 2 102 ? 137.618 143.563 182.954 1.00 74.05  ? 102 CYS D C   1 
ATOM   7141 O O   . CYS D 2 102 ? 137.310 144.529 182.254 1.00 74.05  ? 102 CYS D O   1 
ATOM   7142 C CB  . CYS D 2 102 ? 138.900 144.072 185.009 1.00 74.05  ? 102 CYS D CB  1 
ATOM   7143 S SG  . CYS D 2 102 ? 137.902 145.554 185.111 1.00 74.05  ? 102 CYS D SG  1 
ATOM   7144 N N   . ILE D 2 103 ? 136.798 142.545 183.177 1.00 68.43  ? 103 ILE D N   1 
ATOM   7145 C CA  . ILE D 2 103 ? 135.458 142.487 182.602 1.00 68.43  ? 103 ILE D CA  1 
ATOM   7146 C C   . ILE D 2 103 ? 134.466 142.242 183.724 1.00 68.43  ? 103 ILE D C   1 
ATOM   7147 O O   . ILE D 2 103 ? 134.631 141.310 184.516 1.00 68.43  ? 103 ILE D O   1 
ATOM   7148 C CB  . ILE D 2 103 ? 135.354 141.411 181.518 1.00 68.43  ? 103 ILE D CB  1 
ATOM   7149 C CG1 . ILE D 2 103 ? 136.080 141.881 180.269 1.00 68.43  ? 103 ILE D CG1 1 
ATOM   7150 C CG2 . ILE D 2 103 ? 133.920 141.145 181.186 1.00 68.43  ? 103 ILE D CG2 1 
ATOM   7151 C CD1 . ILE D 2 103 ? 136.047 140.904 179.155 1.00 68.43  ? 103 ILE D CD1 1 
ATOM   7152 N N   . ILE D 2 104 ? 133.436 143.077 183.792 1.00 70.66  ? 104 ILE D N   1 
ATOM   7153 C CA  . ILE D 2 104 ? 132.469 143.055 184.880 1.00 70.66  ? 104 ILE D CA  1 
ATOM   7154 C C   . ILE D 2 104 ? 131.102 142.726 184.301 1.00 70.66  ? 104 ILE D C   1 
ATOM   7155 O O   . ILE D 2 104 ? 130.641 143.386 183.365 1.00 70.66  ? 104 ILE D O   1 
ATOM   7156 C CB  . ILE D 2 104 ? 132.435 144.393 185.625 1.00 70.66  ? 104 ILE D CB  1 
ATOM   7157 C CG1 . ILE D 2 104 ? 133.849 144.833 185.977 1.00 70.66  ? 104 ILE D CG1 1 
ATOM   7158 C CG2 . ILE D 2 104 ? 131.609 144.268 186.878 1.00 70.66  ? 104 ILE D CG2 1 
ATOM   7159 C CD1 . ILE D 2 104 ? 133.936 146.270 186.396 1.00 70.66  ? 104 ILE D CD1 1 
ATOM   7160 N N   . GLU D 2 105 ? 130.449 141.718 184.866 1.00 74.76  ? 105 GLU D N   1 
ATOM   7161 C CA  . GLU D 2 105 ? 129.139 141.298 184.408 1.00 74.76  ? 105 GLU D CA  1 
ATOM   7162 C C   . GLU D 2 105 ? 128.060 142.049 185.172 1.00 74.76  ? 105 GLU D C   1 
ATOM   7163 O O   . GLU D 2 105 ? 128.261 142.446 186.321 1.00 74.76  ? 105 GLU D O   1 
ATOM   7164 C CB  . GLU D 2 105 ? 128.954 139.794 184.603 1.00 74.76  ? 105 GLU D CB  1 
ATOM   7165 C CG  . GLU D 2 105 ? 127.645 139.256 184.059 1.00 74.76  ? 105 GLU D CG  1 
ATOM   7166 C CD  . GLU D 2 105 ? 127.502 137.765 184.224 1.00 74.76  ? 105 GLU D CD  1 
ATOM   7167 O OE1 . GLU D 2 105 ? 128.419 137.137 184.786 1.00 74.76  ? 105 GLU D OE1 1 
ATOM   7168 O OE2 . GLU D 2 105 ? 126.466 137.218 183.800 1.00 74.76  ? 105 GLU D OE2 1 
ATOM   7169 N N   . ASN D 2 106 ? 126.917 142.240 184.529 1.00 78.90  ? 106 ASN D N   1 
ATOM   7170 C CA  . ASN D 2 106 ? 125.750 142.833 185.163 1.00 78.90  ? 106 ASN D CA  1 
ATOM   7171 C C   . ASN D 2 106 ? 124.773 141.710 185.485 1.00 78.90  ? 106 ASN D C   1 
ATOM   7172 O O   . ASN D 2 106 ? 124.110 141.182 184.589 1.00 78.90  ? 106 ASN D O   1 
ATOM   7173 C CB  . ASN D 2 106 ? 125.112 143.875 184.254 1.00 78.90  ? 106 ASN D CB  1 
ATOM   7174 C CG  . ASN D 2 106 ? 124.033 144.655 184.947 1.00 78.90  ? 106 ASN D CG  1 
ATOM   7175 O OD1 . ASN D 2 106 ? 123.728 144.418 186.111 1.00 78.90  ? 106 ASN D OD1 1 
ATOM   7176 N ND2 . ASN D 2 106 ? 123.440 145.590 184.233 1.00 78.90  ? 106 ASN D ND2 1 
ATOM   7177 N N   . ASP D 2 107 ? 124.684 141.346 186.761 1.00 84.25  ? 107 ASP D N   1 
ATOM   7178 C CA  . ASP D 2 107 ? 123.899 140.177 187.137 1.00 84.25  ? 107 ASP D CA  1 
ATOM   7179 C C   . ASP D 2 107 ? 122.403 140.454 187.187 1.00 84.25  ? 107 ASP D C   1 
ATOM   7180 O O   . ASP D 2 107 ? 121.608 139.511 187.133 1.00 84.25  ? 107 ASP D O   1 
ATOM   7181 C CB  . ASP D 2 107 ? 124.373 139.642 188.486 1.00 84.25  ? 107 ASP D CB  1 
ATOM   7182 C CG  . ASP D 2 107 ? 125.504 138.644 188.351 1.00 84.25  ? 107 ASP D CG  1 
ATOM   7183 O OD1 . ASP D 2 107 ? 125.438 137.790 187.444 1.00 84.25  ? 107 ASP D OD1 1 
ATOM   7184 O OD2 . ASP D 2 107 ? 126.460 138.716 189.147 1.00 84.25  ? 107 ASP D OD2 1 
ATOM   7185 N N   . ASN D 2 108 ? 121.992 141.715 187.292 1.00 82.43  ? 108 ASN D N   1 
ATOM   7186 C CA  . ASN D 2 108 ? 120.565 142.004 187.364 1.00 82.43  ? 108 ASN D CA  1 
ATOM   7187 C C   . ASN D 2 108 ? 119.975 142.169 185.972 1.00 82.43  ? 108 ASN D C   1 
ATOM   7188 O O   . ASN D 2 108 ? 119.194 143.093 185.730 1.00 82.43  ? 108 ASN D O   1 
ATOM   7189 C CB  . ASN D 2 108 ? 120.319 143.269 188.181 1.00 82.43  ? 108 ASN D CB  1 
ATOM   7190 C CG  . ASN D 2 108 ? 121.178 143.335 189.419 1.00 82.43  ? 108 ASN D CG  1 
ATOM   7191 O OD1 . ASN D 2 108 ? 121.961 144.267 189.595 1.00 82.43  ? 108 ASN D OD1 1 
ATOM   7192 N ND2 . ASN D 2 108 ? 121.039 142.343 190.286 1.00 82.43  ? 108 ASN D ND2 1 
ATOM   7193 N N   . VAL D 2 109 ? 120.299 141.246 185.074 1.00 74.63  ? 109 VAL D N   1 
ATOM   7194 C CA  . VAL D 2 109 ? 120.027 141.357 183.643 1.00 74.63  ? 109 VAL D CA  1 
ATOM   7195 C C   . VAL D 2 109 ? 120.009 139.969 183.015 1.00 74.63  ? 109 VAL D C   1 
ATOM   7196 O O   . VAL D 2 109 ? 120.957 139.196 183.206 1.00 74.63  ? 109 VAL D O   1 
ATOM   7197 C CB  . VAL D 2 109 ? 121.067 142.245 182.943 1.00 74.63  ? 109 VAL D CB  1 
ATOM   7198 C CG1 . VAL D 2 109 ? 120.876 142.169 181.499 1.00 74.63  ? 109 VAL D CG1 1 
ATOM   7199 C CG2 . VAL D 2 109 ? 120.899 143.695 183.323 1.00 74.63  ? 109 VAL D CG2 1 
ATOM   7200 N N   . PRO D 2 110 ? 118.970 139.610 182.268 1.00 70.37  ? 110 PRO D N   1 
ATOM   7201 C CA  . PRO D 2 110 ? 118.964 138.331 181.561 1.00 70.37  ? 110 PRO D CA  1 
ATOM   7202 C C   . PRO D 2 110 ? 119.847 138.393 180.330 1.00 70.37  ? 110 PRO D C   1 
ATOM   7203 O O   . PRO D 2 110 ? 120.270 139.481 179.918 1.00 70.37  ? 110 PRO D O   1 
ATOM   7204 C CB  . PRO D 2 110 ? 117.490 138.159 181.182 1.00 70.37  ? 110 PRO D CB  1 
ATOM   7205 C CG  . PRO D 2 110 ? 117.010 139.550 181.023 1.00 70.37  ? 110 PRO D CG  1 
ATOM   7206 C CD  . PRO D 2 110 ? 117.702 140.335 182.094 1.00 70.37  ? 110 PRO D CD  1 
ATOM   7207 N N   . PRO D 2 111 ? 120.157 137.249 179.718 1.00 66.81  ? 111 PRO D N   1 
ATOM   7208 C CA  . PRO D 2 111 ? 121.076 137.259 178.569 1.00 66.81  ? 111 PRO D CA  1 
ATOM   7209 C C   . PRO D 2 111 ? 120.625 138.105 177.392 1.00 66.81  ? 111 PRO D C   1 
ATOM   7210 O O   . PRO D 2 111 ? 121.480 138.686 176.717 1.00 66.81  ? 111 PRO D O   1 
ATOM   7211 C CB  . PRO D 2 111 ? 121.162 135.776 178.200 1.00 66.81  ? 111 PRO D CB  1 
ATOM   7212 C CG  . PRO D 2 111 ? 121.001 135.099 179.498 1.00 66.81  ? 111 PRO D CG  1 
ATOM   7213 C CD  . PRO D 2 111 ? 119.943 135.885 180.218 1.00 66.81  ? 111 PRO D CD  1 
ATOM   7214 N N   . VAL D 2 112 ? 119.331 138.191 177.105 1.00 67.62  ? 112 VAL D N   1 
ATOM   7215 C CA  . VAL D 2 112 ? 118.816 139.065 176.052 1.00 67.62  ? 112 VAL D CA  1 
ATOM   7216 C C   . VAL D 2 112 ? 118.078 140.201 176.738 1.00 67.62  ? 112 VAL D C   1 
ATOM   7217 O O   . VAL D 2 112 ? 117.048 139.977 177.383 1.00 67.62  ? 112 VAL D O   1 
ATOM   7218 C CB  . VAL D 2 112 ? 117.901 138.327 175.076 1.00 67.62  ? 112 VAL D CB  1 
ATOM   7219 C CG1 . VAL D 2 112 ? 117.299 139.308 174.102 1.00 67.62  ? 112 VAL D CG1 1 
ATOM   7220 C CG2 . VAL D 2 112 ? 118.675 137.257 174.342 1.00 67.62  ? 112 VAL D CG2 1 
ATOM   7221 N N   . HIS D 2 113 ? 118.607 141.420 176.619 1.00 69.50  ? 113 HIS D N   1 
ATOM   7222 C CA  . HIS D 2 113 ? 118.157 142.474 177.517 1.00 69.50  ? 113 HIS D CA  1 
ATOM   7223 C C   . HIS D 2 113 ? 118.086 143.854 176.883 1.00 69.50  ? 113 HIS D C   1 
ATOM   7224 O O   . HIS D 2 113 ? 117.982 144.849 177.605 1.00 69.50  ? 113 HIS D O   1 
ATOM   7225 C CB  . HIS D 2 113 ? 119.079 142.553 178.707 1.00 69.50  ? 113 HIS D CB  1 
ATOM   7226 C CG  . HIS D 2 113 ? 120.491 142.882 178.347 1.00 69.50  ? 113 HIS D CG  1 
ATOM   7227 N ND1 . HIS D 2 113 ? 121.135 144.003 178.816 1.00 69.50  ? 113 HIS D ND1 1 
ATOM   7228 C CD2 . HIS D 2 113 ? 121.390 142.228 177.578 1.00 69.50  ? 113 HIS D CD2 1 
ATOM   7229 C CE1 . HIS D 2 113 ? 122.367 144.030 178.345 1.00 69.50  ? 113 HIS D CE1 1 
ATOM   7230 N NE2 . HIS D 2 113 ? 122.546 142.967 177.588 1.00 69.50  ? 113 HIS D NE2 1 
ATOM   7231 N N   . TYR D 2 114 ? 118.148 143.957 175.566 1.00 72.48  ? 114 TYR D N   1 
ATOM   7232 C CA  . TYR D 2 114 ? 118.007 145.264 174.960 1.00 72.48  ? 114 TYR D CA  1 
ATOM   7233 C C   . TYR D 2 114 ? 116.671 145.434 174.260 1.00 72.48  ? 114 TYR D C   1 
ATOM   7234 O O   . TYR D 2 114 ? 116.339 144.656 173.358 1.00 72.48  ? 114 TYR D O   1 
ATOM   7235 C CB  . TYR D 2 114 ? 119.144 145.572 173.991 1.00 72.48  ? 114 TYR D CB  1 
ATOM   7236 C CG  . TYR D 2 114 ? 120.441 145.950 174.651 1.00 72.48  ? 114 TYR D CG  1 
ATOM   7237 C CD1 . TYR D 2 114 ? 120.478 146.313 175.981 1.00 72.48  ? 114 TYR D CD1 1 
ATOM   7238 C CD2 . TYR D 2 114 ? 121.613 146.020 173.928 1.00 72.48  ? 114 TYR D CD2 1 
ATOM   7239 C CE1 . TYR D 2 114 ? 121.652 146.699 176.575 1.00 72.48  ? 114 TYR D CE1 1 
ATOM   7240 C CE2 . TYR D 2 114 ? 122.786 146.400 174.514 1.00 72.48  ? 114 TYR D CE2 1 
ATOM   7241 C CZ  . TYR D 2 114 ? 122.801 146.737 175.836 1.00 72.48  ? 114 TYR D CZ  1 
ATOM   7242 O OH  . TYR D 2 114 ? 123.978 147.115 176.422 1.00 72.48  ? 114 TYR D OH  1 
ATOM   7243 N N   . PRO D 2 115 ? 115.883 146.428 174.651 1.00 80.07  ? 115 PRO D N   1 
ATOM   7244 C CA  . PRO D 2 115 ? 114.744 146.832 173.829 1.00 80.07  ? 115 PRO D CA  1 
ATOM   7245 C C   . PRO D 2 115 ? 115.218 147.297 172.469 1.00 80.07  ? 115 PRO D C   1 
ATOM   7246 O O   . PRO D 2 115 ? 116.353 147.742 172.301 1.00 80.07  ? 115 PRO D O   1 
ATOM   7247 C CB  . PRO D 2 115 ? 114.115 147.989 174.610 1.00 80.07  ? 115 PRO D CB  1 
ATOM   7248 C CG  . PRO D 2 115 ? 114.729 147.984 175.940 1.00 80.07  ? 115 PRO D CG  1 
ATOM   7249 C CD  . PRO D 2 115 ? 115.901 147.073 175.970 1.00 80.07  ? 115 PRO D CD  1 
ATOM   7250 N N   . ILE D 2 116 ? 114.328 147.180 171.485 1.00 83.56  ? 116 ILE D N   1 
ATOM   7251 C CA  . ILE D 2 116 ? 114.679 147.538 170.123 1.00 83.56  ? 116 ILE D CA  1 
ATOM   7252 C C   . ILE D 2 116 ? 115.007 149.015 169.973 1.00 83.56  ? 116 ILE D C   1 
ATOM   7253 O O   . ILE D 2 116 ? 115.969 149.364 169.282 1.00 83.56  ? 116 ILE D O   1 
ATOM   7254 C CB  . ILE D 2 116 ? 113.535 147.168 169.164 1.00 83.56  ? 116 ILE D CB  1 
ATOM   7255 C CG1 . ILE D 2 116 ? 113.252 145.671 169.226 1.00 83.56  ? 116 ILE D CG1 1 
ATOM   7256 C CG2 . ILE D 2 116 ? 113.880 147.567 167.748 1.00 83.56  ? 116 ILE D CG2 1 
ATOM   7257 C CD1 . ILE D 2 116 ? 111.984 145.269 168.534 1.00 83.56  ? 116 ILE D CD1 1 
ATOM   7258 N N   . HIS D 2 117 ? 114.240 149.899 170.604 1.00 91.14  ? 117 HIS D N   1 
ATOM   7259 C CA  . HIS D 2 117 ? 114.135 151.249 170.069 1.00 91.14  ? 117 HIS D CA  1 
ATOM   7260 C C   . HIS D 2 117 ? 115.233 152.242 170.437 1.00 91.14  ? 117 HIS D C   1 
ATOM   7261 O O   . HIS D 2 117 ? 116.069 152.558 169.586 1.00 91.14  ? 117 HIS D O   1 
ATOM   7262 C CB  . HIS D 2 117 ? 112.769 151.798 170.476 1.00 91.14  ? 117 HIS D CB  1 
ATOM   7263 C CG  . HIS D 2 117 ? 112.438 151.576 171.917 1.00 91.14  ? 117 HIS D CG  1 
ATOM   7264 N ND1 . HIS D 2 117 ? 112.846 152.423 172.922 1.00 91.14  ? 117 HIS D ND1 1 
ATOM   7265 C CD2 . HIS D 2 117 ? 111.764 150.570 172.524 1.00 91.14  ? 117 HIS D CD2 1 
ATOM   7266 C CE1 . HIS D 2 117 ? 112.414 151.965 174.083 1.00 91.14  ? 117 HIS D CE1 1 
ATOM   7267 N NE2 . HIS D 2 117 ? 111.759 150.839 173.870 1.00 91.14  ? 117 HIS D NE2 1 
ATOM   7268 N N   . GLU D 2 118 ? 115.266 152.759 171.665 1.00 95.39  ? 118 GLU D N   1 
ATOM   7269 C CA  . GLU D 2 118 ? 116.218 153.832 171.913 1.00 95.39  ? 118 GLU D CA  1 
ATOM   7270 C C   . GLU D 2 118 ? 116.824 153.884 173.310 1.00 95.39  ? 118 GLU D C   1 
ATOM   7271 O O   . GLU D 2 118 ? 117.887 154.490 173.470 1.00 95.39  ? 118 GLU D O   1 
ATOM   7272 C CB  . GLU D 2 118 ? 115.554 155.181 171.591 1.00 95.39  ? 118 GLU D CB  1 
ATOM   7273 C CG  . GLU D 2 118 ? 116.491 156.366 171.604 1.00 95.39  ? 118 GLU D CG  1 
ATOM   7274 C CD  . GLU D 2 118 ? 117.559 156.261 170.530 1.00 95.39  ? 118 GLU D CD  1 
ATOM   7275 O OE1 . GLU D 2 118 ? 117.317 155.575 169.513 1.00 95.39  ? 118 GLU D OE1 1 
ATOM   7276 O OE2 . GLU D 2 118 ? 118.638 156.865 170.701 1.00 95.39  ? 118 GLU D OE2 1 
ATOM   7277 N N   . ASP D 2 119 ? 116.220 153.262 174.320 1.00 94.38  ? 119 ASP D N   1 
ATOM   7278 C CA  . ASP D 2 119 ? 116.740 153.346 175.689 1.00 94.38  ? 119 ASP D CA  1 
ATOM   7279 C C   . ASP D 2 119 ? 117.127 151.945 176.179 1.00 94.38  ? 119 ASP D C   1 
ATOM   7280 O O   . ASP D 2 119 ? 116.428 151.282 176.944 1.00 94.38  ? 119 ASP D O   1 
ATOM   7281 C CB  . ASP D 2 119 ? 115.729 154.097 176.616 1.00 94.38  ? 119 ASP D CB  1 
ATOM   7282 C CG  . ASP D 2 119 ? 114.486 153.287 176.959 1.00 94.38  ? 119 ASP D CG  1 
ATOM   7283 O OD1 . ASP D 2 119 ? 113.728 153.726 177.848 1.00 94.38  ? 119 ASP D OD1 1 
ATOM   7284 O OD2 . ASP D 2 119 ? 114.214 152.268 176.297 1.00 94.38  ? 119 ASP D OD2 1 
ATOM   7285 N N   . LYS D 2 120 ? 118.322 151.521 175.773 1.00 84.15  ? 120 LYS D N   1 
ATOM   7286 C CA  . LYS D 2 120 ? 118.706 150.128 175.932 1.00 84.15  ? 120 LYS D CA  1 
ATOM   7287 C C   . LYS D 2 120 ? 118.851 149.739 177.394 1.00 84.15  ? 120 LYS D C   1 
ATOM   7288 O O   . LYS D 2 120 ? 118.535 148.606 177.770 1.00 84.15  ? 120 LYS D O   1 
ATOM   7289 C CB  . LYS D 2 120 ? 120.001 149.872 175.171 1.00 84.15  ? 120 LYS D CB  1 
ATOM   7290 C CG  . LYS D 2 120 ? 119.953 150.353 173.731 1.00 84.15  ? 120 LYS D CG  1 
ATOM   7291 C CD  . LYS D 2 120 ? 118.858 149.650 172.958 1.00 84.15  ? 120 LYS D CD  1 
ATOM   7292 C CE  . LYS D 2 120 ? 118.932 149.971 171.484 1.00 84.15  ? 120 LYS D CE  1 
ATOM   7293 N NZ  . LYS D 2 120 ? 118.612 151.387 171.230 1.00 84.15  ? 120 LYS D NZ  1 
ATOM   7294 N N   . GLY D 2 121 ? 119.306 150.654 178.232 1.00 84.00  ? 121 GLY D N   1 
ATOM   7295 C CA  . GLY D 2 121 ? 119.476 150.366 179.635 1.00 84.00  ? 121 GLY D CA  1 
ATOM   7296 C C   . GLY D 2 121 ? 120.905 150.017 179.995 1.00 84.00  ? 121 GLY D C   1 
ATOM   7297 O O   . GLY D 2 121 ? 121.853 150.249 179.243 1.00 84.00  ? 121 GLY D O   1 
ATOM   7298 N N   . GLU D 2 122 ? 121.050 149.448 181.182 1.00 81.69  ? 122 GLU D N   1 
ATOM   7299 C CA  . GLU D 2 122 ? 122.370 149.169 181.712 1.00 81.69  ? 122 GLU D CA  1 
ATOM   7300 C C   . GLU D 2 122 ? 122.962 147.949 181.004 1.00 81.69  ? 122 GLU D C   1 
ATOM   7301 O O   . GLU D 2 122 ? 122.332 146.893 180.947 1.00 81.69  ? 122 GLU D O   1 
ATOM   7302 C CB  . GLU D 2 122 ? 122.272 148.929 183.217 1.00 81.69  ? 122 GLU D CB  1 
ATOM   7303 C CG  . GLU D 2 122 ? 123.581 148.679 183.930 1.00 81.69  ? 122 GLU D CG  1 
ATOM   7304 C CD  . GLU D 2 122 ? 124.493 149.888 183.904 1.00 81.69  ? 122 GLU D CD  1 
ATOM   7305 O OE1 . GLU D 2 122 ? 123.974 151.018 183.791 1.00 81.69  ? 122 GLU D OE1 1 
ATOM   7306 O OE2 . GLU D 2 122 ? 125.727 149.709 183.989 1.00 81.69  ? 122 GLU D OE2 1 
ATOM   7307 N N   . PRO D 2 123 ? 124.171 148.064 180.457 1.00 74.88  ? 123 PRO D N   1 
ATOM   7308 C CA  . PRO D 2 123 ? 124.722 146.981 179.639 1.00 74.88  ? 123 PRO D CA  1 
ATOM   7309 C C   . PRO D 2 123 ? 125.116 145.748 180.433 1.00 74.88  ? 123 PRO D C   1 
ATOM   7310 O O   . PRO D 2 123 ? 125.440 145.804 181.619 1.00 74.88  ? 123 PRO D O   1 
ATOM   7311 C CB  . PRO D 2 123 ? 125.956 147.620 178.986 1.00 74.88  ? 123 PRO D CB  1 
ATOM   7312 C CG  . PRO D 2 123 ? 126.244 148.845 179.746 1.00 74.88  ? 123 PRO D CG  1 
ATOM   7313 C CD  . PRO D 2 123 ? 125.176 149.093 180.754 1.00 74.88  ? 123 PRO D CD  1 
ATOM   7314 N N   . GLY D 2 124 ? 125.081 144.611 179.736 1.00 70.19  ? 124 GLY D N   1 
ATOM   7315 C CA  . GLY D 2 124 ? 125.343 143.339 180.387 1.00 70.19  ? 124 GLY D CA  1 
ATOM   7316 C C   . GLY D 2 124 ? 126.782 143.188 180.836 1.00 70.19  ? 124 GLY D C   1 
ATOM   7317 O O   . GLY D 2 124 ? 127.051 142.698 181.932 1.00 70.19  ? 124 GLY D O   1 
ATOM   7318 N N   . TYR D 2 125 ? 127.726 143.597 179.990 1.00 65.34  ? 125 TYR D N   1 
ATOM   7319 C CA  . TYR D 2 125 ? 129.148 143.496 180.290 1.00 65.34  ? 125 TYR D CA  1 
ATOM   7320 C C   . TYR D 2 125 ? 129.800 144.859 180.143 1.00 65.34  ? 125 TYR D C   1 
ATOM   7321 O O   . TYR D 2 125 ? 129.515 145.583 179.189 1.00 65.34  ? 125 TYR D O   1 
ATOM   7322 C CB  . TYR D 2 125 ? 129.844 142.503 179.371 1.00 65.34  ? 125 TYR D CB  1 
ATOM   7323 C CG  . TYR D 2 125 ? 129.677 141.079 179.797 1.00 65.34  ? 125 TYR D CG  1 
ATOM   7324 C CD1 . TYR D 2 125 ? 130.156 140.645 181.007 1.00 65.34  ? 125 TYR D CD1 1 
ATOM   7325 C CD2 . TYR D 2 125 ? 129.044 140.169 178.983 1.00 65.34  ? 125 TYR D CD2 1 
ATOM   7326 C CE1 . TYR D 2 125 ? 130.004 139.352 181.395 1.00 65.34  ? 125 TYR D CE1 1 
ATOM   7327 C CE2 . TYR D 2 125 ? 128.890 138.874 179.365 1.00 65.34  ? 125 TYR D CE2 1 
ATOM   7328 C CZ  . TYR D 2 125 ? 129.368 138.472 180.573 1.00 65.34  ? 125 TYR D CZ  1 
ATOM   7329 O OH  . TYR D 2 125 ? 129.217 137.171 180.964 1.00 65.34  ? 125 TYR D OH  1 
ATOM   7330 N N   . VAL D 2 126 ? 130.676 145.196 181.082 1.00 68.07  ? 126 VAL D N   1 
ATOM   7331 C CA  . VAL D 2 126 ? 131.431 146.441 181.070 1.00 68.07  ? 126 VAL D CA  1 
ATOM   7332 C C   . VAL D 2 126 ? 132.877 146.111 181.400 1.00 68.07  ? 126 VAL D C   1 
ATOM   7333 O O   . VAL D 2 126 ? 133.139 145.355 182.340 1.00 68.07  ? 126 VAL D O   1 
ATOM   7334 C CB  . VAL D 2 126 ? 130.863 147.454 182.077 1.00 68.07  ? 126 VAL D CB  1 
ATOM   7335 C CG1 . VAL D 2 126 ? 131.859 148.543 182.349 1.00 68.07  ? 126 VAL D CG1 1 
ATOM   7336 C CG2 . VAL D 2 126 ? 129.581 148.045 181.550 1.00 68.07  ? 126 VAL D CG2 1 
ATOM   7337 N N   . ALA D 2 127 ? 133.811 146.665 180.634 1.00 66.53  ? 127 ALA D N   1 
ATOM   7338 C CA  . ALA D 2 127 ? 135.222 146.350 180.794 1.00 66.53  ? 127 ALA D CA  1 
ATOM   7339 C C   . ALA D 2 127 ? 136.057 147.612 180.910 1.00 66.53  ? 127 ALA D C   1 
ATOM   7340 O O   . ALA D 2 127 ? 135.756 148.625 180.279 1.00 66.53  ? 127 ALA D O   1 
ATOM   7341 C CB  . ALA D 2 127 ? 135.735 145.527 179.630 1.00 66.53  ? 127 ALA D CB  1 
ATOM   7342 N N   . TYR D 2 128 ? 137.117 147.529 181.707 1.00 72.49  ? 128 TYR D N   1 
ATOM   7343 C CA  . TYR D 2 128 ? 138.097 148.596 181.888 1.00 72.49  ? 128 TYR D CA  1 
ATOM   7344 C C   . TYR D 2 128 ? 139.419 148.079 181.349 1.00 72.49  ? 128 TYR D C   1 
ATOM   7345 O O   . TYR D 2 128 ? 139.867 147.001 181.739 1.00 72.49  ? 128 TYR D O   1 
ATOM   7346 C CB  . TYR D 2 128 ? 138.243 148.966 183.354 1.00 72.49  ? 128 TYR D CB  1 
ATOM   7347 C CG  . TYR D 2 128 ? 137.160 149.835 183.902 1.00 72.49  ? 128 TYR D CG  1 
ATOM   7348 C CD1 . TYR D 2 128 ? 137.054 151.155 183.529 1.00 72.49  ? 128 TYR D CD1 1 
ATOM   7349 C CD2 . TYR D 2 128 ? 136.248 149.336 184.808 1.00 72.49  ? 128 TYR D CD2 1 
ATOM   7350 C CE1 . TYR D 2 128 ? 136.070 151.950 184.038 1.00 72.49  ? 128 TYR D CE1 1 
ATOM   7351 C CE2 . TYR D 2 128 ? 135.257 150.122 185.319 1.00 72.49  ? 128 TYR D CE2 1 
ATOM   7352 C CZ  . TYR D 2 128 ? 135.172 151.427 184.933 1.00 72.49  ? 128 TYR D CZ  1 
ATOM   7353 O OH  . TYR D 2 128 ? 134.176 152.219 185.445 1.00 72.49  ? 128 TYR D OH  1 
ATOM   7354 N N   . VAL D 2 129 ? 140.053 148.840 180.473 1.00 67.02  ? 129 VAL D N   1 
ATOM   7355 C CA  . VAL D 2 129 ? 141.309 148.441 179.887 1.00 67.02  ? 129 VAL D CA  1 
ATOM   7356 C C   . VAL D 2 129 ? 142.310 149.579 180.038 1.00 67.02  ? 129 VAL D C   1 
ATOM   7357 O O   . VAL D 2 129 ? 141.944 150.734 180.220 1.00 67.02  ? 129 VAL D O   1 
ATOM   7358 C CB  . VAL D 2 129 ? 141.131 148.025 178.416 1.00 67.02  ? 129 VAL D CB  1 
ATOM   7359 C CG1 . VAL D 2 129 ? 140.912 149.226 177.570 1.00 67.02  ? 129 VAL D CG1 1 
ATOM   7360 C CG2 . VAL D 2 129 ? 142.332 147.260 177.932 1.00 67.02  ? 129 VAL D CG2 1 
ATOM   7361 N N   . GLY D 2 130 ? 143.598 149.252 179.985 1.00 69.91  ? 130 GLY D N   1 
ATOM   7362 C CA  . GLY D 2 130 ? 144.630 150.267 180.057 1.00 69.91  ? 130 GLY D CA  1 
ATOM   7363 C C   . GLY D 2 130 ? 146.010 149.747 179.722 1.00 69.91  ? 130 GLY D C   1 
ATOM   7364 O O   . GLY D 2 130 ? 146.139 148.787 178.971 1.00 69.91  ? 130 GLY D O   1 
ATOM   7365 N N   . TYR D 2 131 ? 147.047 150.378 180.266 1.00 71.39  ? 131 TYR D N   1 
ATOM   7366 C CA  . TYR D 2 131 ? 148.417 149.881 180.172 1.00 71.39  ? 131 TYR D CA  1 
ATOM   7367 C C   . TYR D 2 131 ? 148.995 149.743 181.578 1.00 71.39  ? 131 TYR D C   1 
ATOM   7368 O O   . TYR D 2 131 ? 148.273 149.902 182.565 1.00 71.39  ? 131 TYR D O   1 
ATOM   7369 C CB  . TYR D 2 131 ? 149.253 150.800 179.259 1.00 71.39  ? 131 TYR D CB  1 
ATOM   7370 C CG  . TYR D 2 131 ? 149.078 150.630 177.778 1.00 71.39  ? 131 TYR D CG  1 
ATOM   7371 C CD1 . TYR D 2 131 ? 148.548 149.484 177.251 1.00 71.39  ? 131 TYR D CD1 1 
ATOM   7372 C CD2 . TYR D 2 131 ? 149.447 151.629 176.907 1.00 71.39  ? 131 TYR D CD2 1 
ATOM   7373 C CE1 . TYR D 2 131 ? 148.428 149.323 175.897 1.00 71.39  ? 131 TYR D CE1 1 
ATOM   7374 C CE2 . TYR D 2 131 ? 149.311 151.480 175.559 1.00 71.39  ? 131 TYR D CE2 1 
ATOM   7375 C CZ  . TYR D 2 131 ? 148.798 150.328 175.061 1.00 71.39  ? 131 TYR D CZ  1 
ATOM   7376 O OH  . TYR D 2 131 ? 148.661 150.185 173.708 1.00 71.39  ? 131 TYR D OH  1 
ATOM   7377 N N   . ASP D 2 132 ? 150.287 149.446 181.663 1.00 80.95  ? 132 ASP D N   1 
ATOM   7378 C CA  . ASP D 2 132 ? 150.959 149.278 182.937 1.00 80.95  ? 132 ASP D CA  1 
ATOM   7379 C C   . ASP D 2 132 ? 151.575 150.565 183.458 1.00 80.95  ? 132 ASP D C   1 
ATOM   7380 O O   . ASP D 2 132 ? 151.897 150.641 184.648 1.00 80.95  ? 132 ASP D O   1 
ATOM   7381 C CB  . ASP D 2 132 ? 152.039 148.197 182.829 1.00 80.95  ? 132 ASP D CB  1 
ATOM   7382 C CG  . ASP D 2 132 ? 151.466 146.806 182.919 1.00 80.95  ? 132 ASP D CG  1 
ATOM   7383 O OD1 . ASP D 2 132 ? 152.194 145.833 182.638 1.00 80.95  ? 132 ASP D OD1 1 
ATOM   7384 O OD2 . ASP D 2 132 ? 150.280 146.689 183.278 1.00 80.95  ? 132 ASP D OD2 1 
ATOM   7385 N N   . THR D 2 133 ? 151.745 151.577 182.612 1.00 84.65  ? 133 THR D N   1 
ATOM   7386 C CA  . THR D 2 133 ? 152.128 152.895 183.093 1.00 84.65  ? 133 THR D CA  1 
ATOM   7387 C C   . THR D 2 133 ? 151.052 153.519 183.960 1.00 84.65  ? 133 THR D C   1 
ATOM   7388 O O   . THR D 2 133 ? 151.336 154.464 184.702 1.00 84.65  ? 133 THR D O   1 
ATOM   7389 C CB  . THR D 2 133 ? 152.429 153.824 181.919 1.00 84.65  ? 133 THR D CB  1 
ATOM   7390 O OG1 . THR D 2 133 ? 151.202 154.216 181.297 1.00 84.65  ? 133 THR D OG1 1 
ATOM   7391 C CG2 . THR D 2 133 ? 153.292 153.122 180.901 1.00 84.65  ? 133 THR D CG2 1 
ATOM   7392 N N   . ASP D 2 134 ? 149.830 153.011 183.874 1.00 82.58  ? 134 ASP D N   1 
ATOM   7393 C CA  . ASP D 2 134 ? 148.690 153.449 184.660 1.00 82.58  ? 134 ASP D CA  1 
ATOM   7394 C C   . ASP D 2 134 ? 147.874 152.249 185.116 1.00 82.58  ? 134 ASP D C   1 
ATOM   7395 O O   . ASP D 2 134 ? 146.644 152.240 185.054 1.00 82.58  ? 134 ASP D O   1 
ATOM   7396 C CB  . ASP D 2 134 ? 147.861 154.454 183.868 1.00 82.58  ? 134 ASP D CB  1 
ATOM   7397 C CG  . ASP D 2 134 ? 147.283 153.866 182.602 1.00 82.58  ? 134 ASP D CG  1 
ATOM   7398 O OD1 . ASP D 2 134 ? 147.555 152.685 182.310 1.00 82.58  ? 134 ASP D OD1 1 
ATOM   7399 O OD2 . ASP D 2 134 ? 146.584 154.598 181.872 1.00 82.58  ? 134 ASP D OD2 1 
ATOM   7400 N N   . SER D 2 135 ? 148.571 151.211 185.582 1.00 83.71  ? 135 SER D N   1 
ATOM   7401 C CA  . SER D 2 135 ? 147.908 149.991 186.024 1.00 83.71  ? 135 SER D CA  1 
ATOM   7402 C C   . SER D 2 135 ? 147.159 150.189 187.330 1.00 83.71  ? 135 SER D C   1 
ATOM   7403 O O   . SER D 2 135 ? 146.102 149.582 187.537 1.00 83.71  ? 135 SER D O   1 
ATOM   7404 C CB  . SER D 2 135 ? 148.932 148.875 186.191 1.00 83.71  ? 135 SER D CB  1 
ATOM   7405 O OG  . SER D 2 135 ? 148.339 147.745 186.802 1.00 83.71  ? 135 SER D OG  1 
ATOM   7406 N N   . GLU D 2 136 ? 147.714 151.023 188.204 1.00 89.52  ? 136 GLU D N   1 
ATOM   7407 C CA  . GLU D 2 136 ? 147.103 151.308 189.495 1.00 89.52  ? 136 GLU D CA  1 
ATOM   7408 C C   . GLU D 2 136 ? 145.681 151.813 189.302 1.00 89.52  ? 136 GLU D C   1 
ATOM   7409 O O   . GLU D 2 136 ? 144.768 151.424 190.032 1.00 89.52  ? 136 GLU D O   1 
ATOM   7410 C CB  . GLU D 2 136 ? 147.927 152.341 190.264 1.00 89.52  ? 136 GLU D CB  1 
ATOM   7411 C CG  . GLU D 2 136 ? 148.589 151.795 191.519 1.00 89.52  ? 136 GLU D CG  1 
ATOM   7412 C CD  . GLU D 2 136 ? 147.612 151.626 192.666 1.00 89.52  ? 136 GLU D CD  1 
ATOM   7413 O OE1 . GLU D 2 136 ? 146.693 150.790 192.548 1.00 89.52  ? 136 GLU D OE1 1 
ATOM   7414 O OE2 . GLU D 2 136 ? 147.765 152.330 193.687 1.00 89.52  ? 136 GLU D OE2 1 
ATOM   7415 N N   . LEU D 2 137 ? 145.495 152.683 188.314 1.00 84.67  ? 137 LEU D N   1 
ATOM   7416 C CA  . LEU D 2 137 ? 144.173 153.224 188.030 1.00 84.67  ? 137 LEU D CA  1 
ATOM   7417 C C   . LEU D 2 137 ? 143.197 152.122 187.646 1.00 84.67  ? 137 LEU D C   1 
ATOM   7418 O O   . LEU D 2 137 ? 142.060 152.097 188.129 1.00 84.67  ? 137 LEU D O   1 
ATOM   7419 C CB  . LEU D 2 137 ? 144.257 154.271 186.925 1.00 84.67  ? 137 LEU D CB  1 
ATOM   7420 C CG  . LEU D 2 137 ? 142.911 154.848 186.503 1.00 84.67  ? 137 LEU D CG  1 
ATOM   7421 C CD1 . LEU D 2 137 ? 142.217 155.497 187.678 1.00 84.67  ? 137 LEU D CD1 1 
ATOM   7422 C CD2 . LEU D 2 137 ? 143.105 155.839 185.391 1.00 84.67  ? 137 LEU D CD2 1 
ATOM   7423 N N   . VAL D 2 138 ? 143.619 151.201 186.777 1.00 78.80  ? 138 VAL D N   1 
ATOM   7424 C CA  . VAL D 2 138 ? 142.737 150.107 186.383 1.00 78.80  ? 138 VAL D CA  1 
ATOM   7425 C C   . VAL D 2 138 ? 142.396 149.253 187.589 1.00 78.80  ? 138 VAL D C   1 
ATOM   7426 O O   . VAL D 2 138 ? 141.257 148.803 187.748 1.00 78.80  ? 138 VAL D O   1 
ATOM   7427 C CB  . VAL D 2 138 ? 143.372 149.268 185.264 1.00 78.80  ? 138 VAL D CB  1 
ATOM   7428 C CG1 . VAL D 2 138 ? 142.464 148.134 184.896 1.00 78.80  ? 138 VAL D CG1 1 
ATOM   7429 C CG2 . VAL D 2 138 ? 143.642 150.115 184.060 1.00 78.80  ? 138 VAL D CG2 1 
ATOM   7430 N N   . GLN D 2 139 ? 143.376 149.017 188.463 1.00 86.28  ? 139 GLN D N   1 
ATOM   7431 C CA  . GLN D 2 139 ? 143.098 148.302 189.704 1.00 86.28  ? 139 GLN D CA  1 
ATOM   7432 C C   . GLN D 2 139 ? 142.068 149.037 190.548 1.00 86.28  ? 139 GLN D C   1 
ATOM   7433 O O   . GLN D 2 139 ? 141.256 148.409 191.235 1.00 86.28  ? 139 GLN D O   1 
ATOM   7434 C CB  . GLN D 2 139 ? 144.390 148.106 190.493 1.00 86.28  ? 139 GLN D CB  1 
ATOM   7435 C CG  . GLN D 2 139 ? 144.217 147.316 191.776 1.00 86.28  ? 139 GLN D CG  1 
ATOM   7436 C CD  . GLN D 2 139 ? 143.730 145.907 191.542 1.00 86.28  ? 139 GLN D CD  1 
ATOM   7437 O OE1 . GLN D 2 139 ? 142.562 145.597 191.776 1.00 86.28  ? 139 GLN D OE1 1 
ATOM   7438 N NE2 . GLN D 2 139 ? 144.626 145.036 191.095 1.00 86.28  ? 139 GLN D NE2 1 
ATOM   7439 N N   . GLU D 2 140 ? 142.095 150.370 190.519 1.00 87.94  ? 140 GLU D N   1 
ATOM   7440 C CA  . GLU D 2 140 ? 141.121 151.144 191.281 1.00 87.94  ? 140 GLU D CA  1 
ATOM   7441 C C   . GLU D 2 140 ? 139.722 151.037 190.695 1.00 87.94  ? 140 GLU D C   1 
ATOM   7442 O O   . GLU D 2 140 ? 138.755 150.833 191.434 1.00 87.94  ? 140 GLU D O   1 
ATOM   7443 C CB  . GLU D 2 140 ? 141.547 152.606 191.352 1.00 87.94  ? 140 GLU D CB  1 
ATOM   7444 C CG  . GLU D 2 140 ? 142.815 152.836 192.139 1.00 87.94  ? 140 GLU D CG  1 
ATOM   7445 C CD  . GLU D 2 140 ? 142.645 152.526 193.607 1.00 87.94  ? 140 GLU D CD  1 
ATOM   7446 O OE1 . GLU D 2 140 ? 141.527 152.717 194.126 1.00 87.94  ? 140 GLU D OE1 1 
ATOM   7447 O OE2 . GLU D 2 140 ? 143.628 152.091 194.242 1.00 87.94  ? 140 GLU D OE2 1 
ATOM   7448 N N   . LEU D 2 141 ? 139.587 151.183 189.376 1.00 83.13  ? 141 LEU D N   1 
ATOM   7449 C CA  . LEU D 2 141 ? 138.262 151.088 188.770 1.00 83.13  ? 141 LEU D CA  1 
ATOM   7450 C C   . LEU D 2 141 ? 137.690 149.683 188.880 1.00 83.13  ? 141 LEU D C   1 
ATOM   7451 O O   . LEU D 2 141 ? 136.550 149.514 189.323 1.00 83.13  ? 141 LEU D O   1 
ATOM   7452 C CB  . LEU D 2 141 ? 138.310 151.520 187.311 1.00 83.13  ? 141 LEU D CB  1 
ATOM   7453 C CG  . LEU D 2 141 ? 139.106 152.791 187.058 1.00 83.13  ? 141 LEU D CG  1 
ATOM   7454 C CD1 . LEU D 2 141 ? 139.446 152.914 185.596 1.00 83.13  ? 141 LEU D CD1 1 
ATOM   7455 C CD2 . LEU D 2 141 ? 138.310 153.988 187.522 1.00 83.13  ? 141 LEU D CD2 1 
ATOM   7456 N N   . CYS D 2 142 ? 138.456 148.671 188.496 1.00 85.37  ? 142 CYS D N   1 
ATOM   7457 C CA  . CYS D 2 142 ? 138.044 147.286 188.692 1.00 85.37  ? 142 CYS D CA  1 
ATOM   7458 C C   . CYS D 2 142 ? 138.208 146.992 190.172 1.00 85.37  ? 142 CYS D C   1 
ATOM   7459 O O   . CYS D 2 142 ? 139.238 146.484 190.613 1.00 85.37  ? 142 CYS D O   1 
ATOM   7460 C CB  . CYS D 2 142 ? 138.879 146.347 187.839 1.00 85.37  ? 142 CYS D CB  1 
ATOM   7461 S SG  . CYS D 2 142 ? 139.057 146.862 186.134 1.00 85.37  ? 142 CYS D SG  1 
ATOM   7462 N N   . ALA D 2 143 ? 137.181 147.333 190.949 1.00 89.81  ? 143 ALA D N   1 
ATOM   7463 C CA  . ALA D 2 143 ? 137.296 147.293 192.402 1.00 89.81  ? 143 ALA D CA  1 
ATOM   7464 C C   . ALA D 2 143 ? 137.643 145.897 192.896 1.00 89.81  ? 143 ALA D C   1 
ATOM   7465 O O   . ALA D 2 143 ? 138.616 145.702 193.630 1.00 89.81  ? 143 ALA D O   1 
ATOM   7466 C CB  . ALA D 2 143 ? 135.995 147.780 193.038 1.00 89.81  ? 143 ALA D CB  1 
ATOM   7467 N N   . ASP D 2 144 ? 136.859 144.910 192.492 1.00 90.60  ? 144 ASP D N   1 
ATOM   7468 C CA  . ASP D 2 144 ? 137.079 143.552 192.952 1.00 90.60  ? 144 ASP D CA  1 
ATOM   7469 C C   . ASP D 2 144 ? 137.239 142.579 191.796 1.00 90.60  ? 144 ASP D C   1 
ATOM   7470 O O   . ASP D 2 144 ? 137.876 141.536 191.976 1.00 90.60  ? 144 ASP D O   1 
ATOM   7471 C CB  . ASP D 2 144 ? 135.916 143.131 193.877 1.00 90.60  ? 144 ASP D CB  1 
ATOM   7472 C CG  . ASP D 2 144 ? 136.065 141.724 194.442 1.00 90.60  ? 144 ASP D CG  1 
ATOM   7473 O OD1 . ASP D 2 144 ? 136.160 140.742 193.680 1.00 90.60  ? 144 ASP D OD1 1 
ATOM   7474 O OD2 . ASP D 2 144 ? 136.099 141.602 195.683 1.00 90.60  ? 144 ASP D OD2 1 
ATOM   7475 N N   . SER D 2 145 ? 136.747 142.914 190.609 1.00 83.65  ? 145 SER D N   1 
ATOM   7476 C CA  . SER D 2 145 ? 136.852 142.025 189.466 1.00 83.65  ? 145 SER D CA  1 
ATOM   7477 C C   . SER D 2 145 ? 138.306 141.666 189.191 1.00 83.65  ? 145 SER D C   1 
ATOM   7478 O O   . SER D 2 145 ? 139.205 142.502 189.292 1.00 83.65  ? 145 SER D O   1 
ATOM   7479 C CB  . SER D 2 145 ? 136.242 142.683 188.236 1.00 83.65  ? 145 SER D CB  1 
ATOM   7480 O OG  . SER D 2 145 ? 134.857 142.894 188.418 1.00 83.65  ? 145 SER D OG  1 
ATOM   7481 N N   . THR D 2 146 ? 138.530 140.400 188.854 1.00 80.63  ? 146 THR D N   1 
ATOM   7482 C CA  . THR D 2 146 ? 139.880 139.928 188.599 1.00 80.63  ? 146 THR D CA  1 
ATOM   7483 C C   . THR D 2 146 ? 140.488 140.676 187.424 1.00 80.63  ? 146 THR D C   1 
ATOM   7484 O O   . THR D 2 146 ? 139.834 140.898 186.404 1.00 80.63  ? 146 THR D O   1 
ATOM   7485 C CB  . THR D 2 146 ? 139.866 138.431 188.314 1.00 80.63  ? 146 THR D CB  1 
ATOM   7486 O OG1 . THR D 2 146 ? 139.364 137.735 189.459 1.00 80.63  ? 146 THR D OG1 1 
ATOM   7487 C CG2 . THR D 2 146 ? 141.267 137.941 188.016 1.00 80.63  ? 146 THR D CG2 1 
ATOM   7488 N N   . ILE D 2 147 ? 141.746 141.077 187.578 1.00 74.91  ? 147 ILE D N   1 
ATOM   7489 C CA  . ILE D 2 147 ? 142.491 141.786 186.547 1.00 74.91  ? 147 ILE D CA  1 
ATOM   7490 C C   . ILE D 2 147 ? 143.192 140.759 185.677 1.00 74.91  ? 147 ILE D C   1 
ATOM   7491 O O   . ILE D 2 147 ? 143.850 139.849 186.191 1.00 74.91  ? 147 ILE D O   1 
ATOM   7492 C CB  . ILE D 2 147 ? 143.513 142.758 187.153 1.00 74.91  ? 147 ILE D CB  1 
ATOM   7493 C CG1 . ILE D 2 147 ? 142.817 143.769 188.043 1.00 74.91  ? 147 ILE D CG1 1 
ATOM   7494 C CG2 . ILE D 2 147 ? 144.225 143.496 186.057 1.00 74.91  ? 147 ILE D CG2 1 
ATOM   7495 C CD1 . ILE D 2 147 ? 141.977 144.724 187.277 1.00 74.91  ? 147 ILE D CD1 1 
ATOM   7496 N N   . TYR D 2 148 ? 143.053 140.901 184.368 1.00 71.05  ? 148 TYR D N   1 
ATOM   7497 C CA  . TYR D 2 148 ? 143.726 140.040 183.413 1.00 71.05  ? 148 TYR D CA  1 
ATOM   7498 C C   . TYR D 2 148 ? 144.874 140.808 182.785 1.00 71.05  ? 148 TYR D C   1 
ATOM   7499 O O   . TYR D 2 148 ? 144.761 142.015 182.561 1.00 71.05  ? 148 TYR D O   1 
ATOM   7500 C CB  . TYR D 2 148 ? 142.758 139.570 182.334 1.00 71.05  ? 148 TYR D CB  1 
ATOM   7501 C CG  . TYR D 2 148 ? 141.669 138.688 182.858 1.00 71.05  ? 148 TYR D CG  1 
ATOM   7502 C CD1 . TYR D 2 148 ? 141.941 137.411 183.295 1.00 71.05  ? 148 TYR D CD1 1 
ATOM   7503 C CD2 . TYR D 2 148 ? 140.372 139.142 182.940 1.00 71.05  ? 148 TYR D CD2 1 
ATOM   7504 C CE1 . TYR D 2 148 ? 140.952 136.609 183.781 1.00 71.05  ? 148 TYR D CE1 1 
ATOM   7505 C CE2 . TYR D 2 148 ? 139.376 138.347 183.428 1.00 71.05  ? 148 TYR D CE2 1 
ATOM   7506 C CZ  . TYR D 2 148 ? 139.671 137.083 183.846 1.00 71.05  ? 148 TYR D CZ  1 
ATOM   7507 O OH  . TYR D 2 148 ? 138.672 136.287 184.335 1.00 71.05  ? 148 TYR D OH  1 
ATOM   7508 N N   . HIS D 2 149 ? 145.974 140.118 182.510 1.00 67.25  ? 149 HIS D N   1 
ATOM   7509 C CA  . HIS D 2 149 ? 147.126 140.725 181.866 1.00 67.25  ? 149 HIS D CA  1 
ATOM   7510 C C   . HIS D 2 149 ? 147.323 140.128 180.484 1.00 67.25  ? 149 HIS D C   1 
ATOM   7511 O O   . HIS D 2 149 ? 146.832 139.039 180.190 1.00 67.25  ? 149 HIS D O   1 
ATOM   7512 C CB  . HIS D 2 149 ? 148.385 140.536 182.702 1.00 67.25  ? 149 HIS D CB  1 
ATOM   7513 C CG  . HIS D 2 149 ? 148.232 140.978 184.120 1.00 67.25  ? 149 HIS D CG  1 
ATOM   7514 N ND1 . HIS D 2 149 ? 148.385 142.289 184.510 1.00 67.25  ? 149 HIS D ND1 1 
ATOM   7515 C CD2 . HIS D 2 149 ? 147.935 140.284 185.242 1.00 67.25  ? 149 HIS D CD2 1 
ATOM   7516 C CE1 . HIS D 2 149 ? 148.187 142.385 185.812 1.00 67.25  ? 149 HIS D CE1 1 
ATOM   7517 N NE2 . HIS D 2 149 ? 147.914 141.182 186.280 1.00 67.25  ? 149 HIS D NE2 1 
ATOM   7518 N N   . MET D 2 150 ? 148.032 140.857 179.636 1.00 65.79  ? 150 MET D N   1 
ATOM   7519 C CA  . MET D 2 150 ? 148.259 140.429 178.270 1.00 65.79  ? 150 MET D CA  1 
ATOM   7520 C C   . MET D 2 150 ? 149.648 140.826 177.805 1.00 65.79  ? 150 MET D C   1 
ATOM   7521 O O   . MET D 2 150 ? 150.462 141.319 178.581 1.00 65.79  ? 150 MET D O   1 
ATOM   7522 C CB  . MET D 2 150 ? 147.218 141.033 177.343 1.00 65.79  ? 150 MET D CB  1 
ATOM   7523 C CG  . MET D 2 150 ? 145.852 140.427 177.445 1.00 65.79  ? 150 MET D CG  1 
ATOM   7524 S SD  . MET D 2 150 ? 145.052 140.449 175.845 1.00 65.79  ? 150 MET D SD  1 
ATOM   7525 C CE  . MET D 2 150 ? 143.653 139.405 176.178 1.00 65.79  ? 150 MET D CE  1 
ATOM   7526 O OXT . MET D 2 150 ? 149.988 140.664 176.636 1.00 65.79  ? 150 MET D OXT 1 
HETATM 7527 C C31 . 6PL E 3 .   ? 158.432 168.818 152.818 1.00 70.09  ? 501 6PL A C31 1 
HETATM 7528 C C32 . 6PL E 3 .   ? 158.221 168.666 151.290 1.00 70.09  ? 501 6PL A C32 1 
HETATM 7529 C C33 . 6PL E 3 .   ? 159.455 167.972 150.657 1.00 70.09  ? 501 6PL A C33 1 
HETATM 7530 C C34 . 6PL E 3 .   ? 159.009 166.672 149.923 1.00 70.09  ? 501 6PL A C34 1 
HETATM 7531 C C35 . 6PL E 3 .   ? 160.118 166.227 148.935 1.00 70.09  ? 501 6PL A C35 1 
HETATM 7532 C C36 . 6PL E 3 .   ? 159.541 165.207 147.917 1.00 70.09  ? 501 6PL A C36 1 
HETATM 7533 C C37 . 6PL E 3 .   ? 160.465 165.168 146.671 1.00 70.09  ? 501 6PL A C37 1 
HETATM 7534 C C38 . 6PL E 3 .   ? 159.775 164.367 145.527 1.00 70.09  ? 501 6PL A C38 1 
HETATM 7535 C C39 . 6PL E 3 .   ? 160.771 164.170 144.358 1.00 70.09  ? 501 6PL A C39 1 
HETATM 7536 C C40 . 6PL E 3 .   ? 160.567 162.772 143.714 1.00 70.09  ? 501 6PL A C40 1 
HETATM 7537 C C41 . 6PL E 3 .   ? 161.731 162.472 142.732 1.00 70.09  ? 501 6PL A C41 1 
HETATM 7538 C C42 . 6PL E 3 .   ? 162.175 160.998 142.920 1.00 70.09  ? 501 6PL A C42 1 
HETATM 7539 C C43 . 6PL E 3 .   ? 163.538 160.759 142.234 1.00 70.09  ? 501 6PL A C43 1 
HETATM 7540 C C44 . 6PL E 3 .   ? 164.206 159.511 142.839 1.00 70.09  ? 501 6PL A C44 1 
HETATM 7541 C C45 . 6PL E 3 .   ? 165.281 158.975 141.878 1.00 70.09  ? 501 6PL A C45 1 
HETATM 7542 C C46 . 6PL E 3 .   ? 164.630 158.015 140.869 1.00 70.09  ? 501 6PL A C46 1 
HETATM 7543 C C47 . 6PL E 3 .   ? 165.193 158.311 139.471 1.00 70.09  ? 501 6PL A C47 1 
HETATM 7544 C C48 . 6PL E 3 .   ? 164.702 157.259 138.475 1.00 70.09  ? 501 6PL A C48 1 
HETATM 7545 C C31 . 6PL F 3 .   ? 152.877 132.745 154.159 1.00 73.48  ? 502 6PL A C31 1 
HETATM 7546 C C32 . 6PL F 3 .   ? 153.341 133.717 155.272 1.00 73.48  ? 502 6PL A C32 1 
HETATM 7547 C C33 . 6PL F 3 .   ? 154.887 133.701 155.393 1.00 73.48  ? 502 6PL A C33 1 
HETATM 7548 C C34 . 6PL F 3 .   ? 155.429 135.099 154.982 1.00 73.48  ? 502 6PL A C34 1 
HETATM 7549 C C35 . 6PL F 3 .   ? 155.181 135.297 153.466 1.00 73.48  ? 502 6PL A C35 1 
HETATM 7550 C C36 . 6PL F 3 .   ? 155.702 136.687 153.022 1.00 73.48  ? 502 6PL A C36 1 
HETATM 7551 C C37 . 6PL F 3 .   ? 157.206 136.787 153.378 1.00 73.48  ? 502 6PL A C37 1 
HETATM 7552 C C38 . 6PL F 3 .   ? 157.843 137.955 152.573 1.00 73.48  ? 502 6PL A C38 1 
HETATM 7553 C C39 . 6PL F 3 .   ? 157.996 137.514 151.102 1.00 73.48  ? 502 6PL A C39 1 
HETATM 7554 C C40 . 6PL F 3 .   ? 159.282 138.149 150.518 1.00 73.48  ? 502 6PL A C40 1 
HETATM 7555 C C41 . 6PL F 3 .   ? 158.920 139.487 149.822 1.00 73.48  ? 502 6PL A C41 1 
HETATM 7556 C C42 . 6PL F 3 .   ? 160.083 139.891 148.881 1.00 73.48  ? 502 6PL A C42 1 
HETATM 7557 C C43 . 6PL F 3 .   ? 161.395 139.852 149.681 1.00 73.48  ? 502 6PL A C43 1 
HETATM 7558 C C44 . 6PL F 3 .   ? 162.567 139.951 148.696 1.00 73.48  ? 502 6PL A C44 1 
HETATM 7559 C C45 . 6PL F 3 .   ? 162.667 141.398 148.192 1.00 73.48  ? 502 6PL A C45 1 
HETATM 7560 C C46 . 6PL F 3 .   ? 163.695 141.492 147.055 1.00 73.48  ? 502 6PL A C46 1 
HETATM 7561 C C47 . 6PL F 3 .   ? 164.420 142.842 147.139 1.00 73.48  ? 502 6PL A C47 1 
HETATM 7562 C C48 . 6PL F 3 .   ? 164.661 143.397 145.733 1.00 73.48  ? 502 6PL A C48 1 
HETATM 7563 C C26 . 6PL G 3 .   ? 152.875 134.937 150.522 1.00 79.18  ? 201 6PL B C26 1 
HETATM 7564 C C25 . 6PL G 3 .   ? 152.088 136.248 150.519 1.00 79.18  ? 201 6PL B C25 1 
HETATM 7565 C C24 . 6PL G 3 .   ? 150.775 136.046 149.757 1.00 79.18  ? 201 6PL B C24 1 
HETATM 7566 C C23 . 6PL G 3 .   ? 150.106 137.411 149.510 1.00 79.18  ? 201 6PL B C23 1 
HETATM 7567 C C22 . 6PL G 3 .   ? 148.872 137.231 148.607 1.00 79.18  ? 201 6PL B C22 1 
HETATM 7568 C C21 . 6PL G 3 .   ? 147.797 136.425 149.358 1.00 79.18  ? 201 6PL B C21 1 
HETATM 7569 C C20 . 6PL G 3 .   ? 146.416 137.067 149.135 1.00 79.18  ? 201 6PL B C20 1 
HETATM 7570 C C19 . 6PL G 3 .   ? 145.407 136.443 150.113 1.00 79.18  ? 201 6PL B C19 1 
HETATM 7571 C C18 . 6PL G 3 .   ? 144.117 137.276 150.137 1.00 79.18  ? 201 6PL B C18 1 
HETATM 7572 C C17 . 6PL G 3 .   ? 143.365 137.008 151.455 1.00 79.18  ? 201 6PL B C17 1 
HETATM 7573 C C16 . 6PL G 3 .   ? 144.348 137.145 152.626 1.00 79.18  ? 201 6PL B C16 1 
HETATM 7574 C C15 . 6PL G 3 .   ? 143.974 136.127 153.732 1.00 79.18  ? 201 6PL B C15 1 
HETATM 7575 C C14 . 6PL G 3 .   ? 143.088 136.827 154.779 1.00 79.18  ? 201 6PL B C14 1 
HETATM 7576 C C13 . 6PL G 3 .   ? 143.781 136.708 156.150 1.00 79.18  ? 201 6PL B C13 1 
HETATM 7577 C C12 . 6PL G 3 .   ? 143.901 135.199 156.483 1.00 79.18  ? 201 6PL B C12 1 
HETATM 7578 C C11 . 6PL G 3 .   ? 143.078 134.939 157.774 1.00 79.18  ? 201 6PL B C11 1 
HETATM 7579 O O11 . 6PL G 3 .   ? 142.634 135.876 158.350 1.00 79.18  ? 201 6PL B O11 1 
HETATM 7580 O O3  . 6PL G 3 .   ? 142.868 133.586 158.237 1.00 79.18  ? 201 6PL B O3  1 
HETATM 7581 C C3  . 6PL G 3 .   ? 142.510 133.452 159.601 1.00 79.18  ? 201 6PL B C3  1 
HETATM 7582 C C2  . 6PL G 3 .   ? 141.021 133.804 159.754 1.00 79.18  ? 201 6PL B C2  1 
HETATM 7583 C C1  . 6PL G 3 .   ? 140.446 133.166 161.014 1.00 79.18  ? 201 6PL B C1  1 
HETATM 7584 O O3P . 6PL G 3 .   ? 139.551 134.118 161.548 1.00 79.18  ? 201 6PL B O3P 1 
HETATM 7585 P P   . 6PL G 3 .   ? 138.298 133.569 162.491 1.00 79.18  ? 201 6PL B P   1 
HETATM 7586 O O1P . 6PL G 3 .   ? 137.534 132.512 161.734 1.00 79.18  ? 201 6PL B O1P 1 
HETATM 7587 O O2P . 6PL G 3 .   ? 138.882 132.963 163.741 1.00 79.18  ? 201 6PL B O2P 1 
HETATM 7588 O O4P . 6PL G 3 .   ? 137.321 134.857 162.853 1.00 79.18  ? 201 6PL B O4P 1 
HETATM 7589 O O2  . 6PL G 3 .   ? 140.330 133.349 158.644 1.00 79.18  ? 201 6PL B O2  1 
HETATM 7590 C C31 . 6PL G 3 .   ? 139.186 134.135 158.344 1.00 79.18  ? 201 6PL B C31 1 
HETATM 7591 O O31 . 6PL G 3 .   ? 138.119 133.759 158.666 1.00 79.18  ? 201 6PL B O31 1 
HETATM 7592 C C32 . 6PL G 3 .   ? 139.328 135.478 157.597 1.00 79.18  ? 201 6PL B C32 1 
HETATM 7593 C C33 . 6PL G 3 .   ? 138.129 135.633 156.625 1.00 79.18  ? 201 6PL B C33 1 
HETATM 7594 C C34 . 6PL G 3 .   ? 138.169 134.504 155.551 1.00 79.18  ? 201 6PL B C34 1 
HETATM 7595 C C35 . 6PL G 3 .   ? 139.589 134.430 154.936 1.00 79.18  ? 201 6PL B C35 1 
HETATM 7596 C C36 . 6PL G 3 .   ? 139.512 134.011 153.445 1.00 79.18  ? 201 6PL B C36 1 
HETATM 7597 C C37 . 6PL G 3 .   ? 139.956 135.209 152.558 1.00 79.18  ? 201 6PL B C37 1 
HETATM 7598 C C38 . 6PL G 3 .   ? 138.740 136.159 152.335 1.00 79.18  ? 201 6PL B C38 1 
HETATM 7599 C C39 . 6PL G 3 .   ? 139.228 137.605 152.068 1.00 79.18  ? 201 6PL B C39 1 
HETATM 7600 C C40 . 6PL G 3 .   ? 139.471 137.831 150.551 1.00 79.18  ? 201 6PL B C40 1 
HETATM 7601 C C41 . 6PL G 3 .   ? 139.583 139.359 150.276 1.00 79.18  ? 201 6PL B C41 1 
HETATM 7602 C C42 . 6PL G 3 .   ? 140.318 139.607 148.928 1.00 79.18  ? 201 6PL B C42 1 
HETATM 7603 C C31 . 6PL H 3 .   ? 150.932 149.421 156.361 1.00 68.70  ? 202 6PL B C31 1 
HETATM 7604 C C32 . 6PL H 3 .   ? 151.696 149.045 155.066 1.00 68.70  ? 202 6PL B C32 1 
HETATM 7605 C C33 . 6PL H 3 .   ? 150.871 149.486 153.827 1.00 68.70  ? 202 6PL B C33 1 
HETATM 7606 C C34 . 6PL H 3 .   ? 151.821 149.721 152.616 1.00 68.70  ? 202 6PL B C34 1 
HETATM 7607 C C35 . 6PL H 3 .   ? 150.987 150.177 151.393 1.00 68.70  ? 202 6PL B C35 1 
HETATM 7608 C C36 . 6PL H 3 .   ? 151.863 151.073 150.478 1.00 68.70  ? 202 6PL B C36 1 
HETATM 7609 C C37 . 6PL H 3 .   ? 151.811 150.549 149.018 1.00 68.70  ? 202 6PL B C37 1 
HETATM 7610 C C38 . 6PL H 3 .   ? 152.918 151.249 148.175 1.00 68.70  ? 202 6PL B C38 1 
HETATM 7611 C C39 . 6PL H 3 .   ? 153.336 150.330 147.004 1.00 68.70  ? 202 6PL B C39 1 
HETATM 7612 C C40 . 6PL H 3 .   ? 154.328 151.088 146.085 1.00 68.70  ? 202 6PL B C40 1 
HETATM 7613 C C41 . 6PL H 3 .   ? 154.869 150.129 144.985 1.00 68.70  ? 202 6PL B C41 1 
HETATM 7614 C C42 . 6PL H 3 .   ? 153.910 150.122 143.760 1.00 68.70  ? 202 6PL B C42 1 
HETATM 7615 C C43 . 6PL H 3 .   ? 154.542 149.306 142.610 1.00 68.70  ? 202 6PL B C43 1 
HETATM 7616 C C44 . 6PL H 3 .   ? 153.432 148.723 141.715 1.00 68.70  ? 202 6PL B C44 1 
HETATM 7617 C C45 . 6PL H 3 .   ? 153.669 147.214 141.508 1.00 68.70  ? 202 6PL B C45 1 
HETATM 7618 C C46 . 6PL H 3 .   ? 152.329 146.494 141.276 1.00 68.70  ? 202 6PL B C46 1 
HETATM 7619 C C47 . 6PL H 3 .   ? 152.505 144.975 141.437 1.00 68.70  ? 202 6PL B C47 1 
HETATM 7620 C C48 . 6PL H 3 .   ? 153.153 144.397 140.178 1.00 68.70  ? 202 6PL B C48 1 
HETATM 7621 C C31 . 6PL I 3 .   ? 116.015 105.622 152.829 1.00 70.09  ? 501 6PL C C31 1 
HETATM 7622 C C32 . 6PL I 3 .   ? 116.225 105.774 151.301 1.00 70.09  ? 501 6PL C C32 1 
HETATM 7623 C C33 . 6PL I 3 .   ? 114.991 106.468 150.668 1.00 70.09  ? 501 6PL C C33 1 
HETATM 7624 C C34 . 6PL I 3 .   ? 115.438 107.768 149.934 1.00 70.09  ? 501 6PL C C34 1 
HETATM 7625 C C35 . 6PL I 3 .   ? 114.329 108.213 148.946 1.00 70.09  ? 501 6PL C C35 1 
HETATM 7626 C C36 . 6PL I 3 .   ? 114.905 109.233 147.928 1.00 70.09  ? 501 6PL C C36 1 
HETATM 7627 C C37 . 6PL I 3 .   ? 113.981 109.273 146.682 1.00 70.09  ? 501 6PL C C37 1 
HETATM 7628 C C38 . 6PL I 3 .   ? 114.671 110.073 145.538 1.00 70.09  ? 501 6PL C C38 1 
HETATM 7629 C C39 . 6PL I 3 .   ? 113.675 110.270 144.369 1.00 70.09  ? 501 6PL C C39 1 
HETATM 7630 C C40 . 6PL I 3 .   ? 113.880 111.667 143.725 1.00 70.09  ? 501 6PL C C40 1 
HETATM 7631 C C41 . 6PL I 3 .   ? 112.715 111.967 142.742 1.00 70.09  ? 501 6PL C C41 1 
HETATM 7632 C C42 . 6PL I 3 .   ? 112.271 113.442 142.930 1.00 70.09  ? 501 6PL C C42 1 
HETATM 7633 C C43 . 6PL I 3 .   ? 110.908 113.680 142.245 1.00 70.09  ? 501 6PL C C43 1 
HETATM 7634 C C44 . 6PL I 3 .   ? 110.240 114.928 142.850 1.00 70.09  ? 501 6PL C C44 1 
HETATM 7635 C C45 . 6PL I 3 .   ? 109.165 115.465 141.889 1.00 70.09  ? 501 6PL C C45 1 
HETATM 7636 C C46 . 6PL I 3 .   ? 109.817 116.424 140.880 1.00 70.09  ? 501 6PL C C46 1 
HETATM 7637 C C47 . 6PL I 3 .   ? 109.253 116.128 139.482 1.00 70.09  ? 501 6PL C C47 1 
HETATM 7638 C C48 . 6PL I 3 .   ? 109.743 117.180 138.486 1.00 70.09  ? 501 6PL C C48 1 
HETATM 7639 C C31 . 6PL J 3 .   ? 121.570 141.694 154.169 1.00 73.48  ? 502 6PL C C31 1 
HETATM 7640 C C32 . 6PL J 3 .   ? 121.106 140.722 155.282 1.00 73.48  ? 502 6PL C C32 1 
HETATM 7641 C C33 . 6PL J 3 .   ? 119.560 140.739 155.402 1.00 73.48  ? 502 6PL C C33 1 
HETATM 7642 C C34 . 6PL J 3 .   ? 119.018 139.341 154.991 1.00 73.48  ? 502 6PL C C34 1 
HETATM 7643 C C35 . 6PL J 3 .   ? 119.266 139.143 153.475 1.00 73.48  ? 502 6PL C C35 1 
HETATM 7644 C C36 . 6PL J 3 .   ? 118.744 137.753 153.031 1.00 73.48  ? 502 6PL C C36 1 
HETATM 7645 C C37 . 6PL J 3 .   ? 117.241 137.653 153.387 1.00 73.48  ? 502 6PL C C37 1 
HETATM 7646 C C38 . 6PL J 3 .   ? 116.604 136.485 152.582 1.00 73.48  ? 502 6PL C C38 1 
HETATM 7647 C C39 . 6PL J 3 .   ? 116.451 136.926 151.111 1.00 73.48  ? 502 6PL C C39 1 
HETATM 7648 C C40 . 6PL J 3 .   ? 115.165 136.291 150.529 1.00 73.48  ? 502 6PL C C40 1 
HETATM 7649 C C41 . 6PL J 3 .   ? 115.526 134.953 149.832 1.00 73.48  ? 502 6PL C C41 1 
HETATM 7650 C C42 . 6PL J 3 .   ? 114.364 134.549 148.892 1.00 73.48  ? 502 6PL C C42 1 
HETATM 7651 C C43 . 6PL J 3 .   ? 113.052 134.588 149.691 1.00 73.48  ? 502 6PL C C43 1 
HETATM 7652 C C44 . 6PL J 3 .   ? 111.879 134.489 148.706 1.00 73.48  ? 502 6PL C C44 1 
HETATM 7653 C C45 . 6PL J 3 .   ? 111.779 133.042 148.202 1.00 73.48  ? 502 6PL C C45 1 
HETATM 7654 C C46 . 6PL J 3 .   ? 110.751 132.948 147.065 1.00 73.48  ? 502 6PL C C46 1 
HETATM 7655 C C47 . 6PL J 3 .   ? 110.026 131.598 147.149 1.00 73.48  ? 502 6PL C C47 1 
HETATM 7656 C C48 . 6PL J 3 .   ? 109.786 131.043 145.743 1.00 73.48  ? 502 6PL C C48 1 
HETATM 7657 C C26 . 6PL K 3 .   ? 121.572 139.502 150.532 1.00 79.18  ? 201 6PL D C26 1 
HETATM 7658 C C25 . 6PL K 3 .   ? 122.359 138.192 150.529 1.00 79.18  ? 201 6PL D C25 1 
HETATM 7659 C C24 . 6PL K 3 .   ? 123.672 138.394 149.765 1.00 79.18  ? 201 6PL D C24 1 
HETATM 7660 C C23 . 6PL K 3 .   ? 124.341 137.029 149.519 1.00 79.18  ? 201 6PL D C23 1 
HETATM 7661 C C22 . 6PL K 3 .   ? 125.575 137.209 148.616 1.00 79.18  ? 201 6PL D C22 1 
HETATM 7662 C C21 . 6PL K 3 .   ? 126.650 138.015 149.367 1.00 79.18  ? 201 6PL D C21 1 
HETATM 7663 C C20 . 6PL K 3 .   ? 128.030 137.373 149.144 1.00 79.18  ? 201 6PL D C20 1 
HETATM 7664 C C19 . 6PL K 3 .   ? 129.040 137.997 150.122 1.00 79.18  ? 201 6PL D C19 1 
HETATM 7665 C C18 . 6PL K 3 .   ? 130.330 137.164 150.146 1.00 79.18  ? 201 6PL D C18 1 
HETATM 7666 C C17 . 6PL K 3 .   ? 131.082 137.432 151.463 1.00 79.18  ? 201 6PL D C17 1 
HETATM 7667 C C16 . 6PL K 3 .   ? 130.099 137.295 152.635 1.00 79.18  ? 201 6PL D C16 1 
HETATM 7668 C C15 . 6PL K 3 .   ? 130.473 138.313 153.741 1.00 79.18  ? 201 6PL D C15 1 
HETATM 7669 C C14 . 6PL K 3 .   ? 131.359 137.613 154.787 1.00 79.18  ? 201 6PL D C14 1 
HETATM 7670 C C13 . 6PL K 3 .   ? 130.667 137.732 156.158 1.00 79.18  ? 201 6PL D C13 1 
HETATM 7671 C C12 . 6PL K 3 .   ? 130.547 139.240 156.492 1.00 79.18  ? 201 6PL D C12 1 
HETATM 7672 C C11 . 6PL K 3 .   ? 131.369 139.502 157.782 1.00 79.18  ? 201 6PL D C11 1 
HETATM 7673 O O11 . 6PL K 3 .   ? 131.814 138.564 158.358 1.00 79.18  ? 201 6PL D O11 1 
HETATM 7674 O O3  . 6PL K 3 .   ? 131.579 140.854 158.245 1.00 79.18  ? 201 6PL D O3  1 
HETATM 7675 C C3  . 6PL K 3 .   ? 131.938 140.988 159.609 1.00 79.18  ? 201 6PL D C3  1 
HETATM 7676 C C2  . 6PL K 3 .   ? 133.426 140.636 159.762 1.00 79.18  ? 201 6PL D C2  1 
HETATM 7677 C C1  . 6PL K 3 .   ? 134.002 141.274 161.022 1.00 79.18  ? 201 6PL D C1  1 
HETATM 7678 O O3P . 6PL K 3 .   ? 134.896 140.322 161.557 1.00 79.18  ? 201 6PL D O3P 1 
HETATM 7679 P P   . 6PL K 3 .   ? 136.150 140.871 162.500 1.00 79.18  ? 201 6PL D P   1 
HETATM 7680 O O1P . 6PL K 3 .   ? 136.913 141.928 161.743 1.00 79.18  ? 201 6PL D O1P 1 
HETATM 7681 O O2P . 6PL K 3 .   ? 135.565 141.477 163.750 1.00 79.18  ? 201 6PL D O2P 1 
HETATM 7682 O O4P . 6PL K 3 .   ? 137.126 139.583 162.862 1.00 79.18  ? 201 6PL D O4P 1 
HETATM 7683 O O2  . 6PL K 3 .   ? 134.117 141.092 158.652 1.00 79.18  ? 201 6PL D O2  1 
HETATM 7684 C C31 . 6PL K 3 .   ? 135.261 140.306 158.353 1.00 79.18  ? 201 6PL D C31 1 
HETATM 7685 O O31 . 6PL K 3 .   ? 136.328 140.681 158.675 1.00 79.18  ? 201 6PL D O31 1 
HETATM 7686 C C32 . 6PL K 3 .   ? 135.119 138.961 157.606 1.00 79.18  ? 201 6PL D C32 1 
HETATM 7687 C C33 . 6PL K 3 .   ? 136.317 138.807 156.634 1.00 79.18  ? 201 6PL D C33 1 
HETATM 7688 C C34 . 6PL K 3 .   ? 136.279 139.936 155.560 1.00 79.18  ? 201 6PL D C34 1 
HETATM 7689 C C35 . 6PL K 3 .   ? 134.858 140.010 154.945 1.00 79.18  ? 201 6PL D C35 1 
HETATM 7690 C C36 . 6PL K 3 .   ? 134.935 140.428 153.454 1.00 79.18  ? 201 6PL D C36 1 
HETATM 7691 C C37 . 6PL K 3 .   ? 134.491 139.231 152.567 1.00 79.18  ? 201 6PL D C37 1 
HETATM 7692 C C38 . 6PL K 3 .   ? 135.707 138.281 152.344 1.00 79.18  ? 201 6PL D C38 1 
HETATM 7693 C C39 . 6PL K 3 .   ? 135.219 136.835 152.077 1.00 79.18  ? 201 6PL D C39 1 
HETATM 7694 C C40 . 6PL K 3 .   ? 134.976 136.609 150.560 1.00 79.18  ? 201 6PL D C40 1 
HETATM 7695 C C41 . 6PL K 3 .   ? 134.864 135.081 150.285 1.00 79.18  ? 201 6PL D C41 1 
HETATM 7696 C C42 . 6PL K 3 .   ? 134.129 134.833 148.937 1.00 79.18  ? 201 6PL D C42 1 
HETATM 7697 C C31 . 6PL L 3 .   ? 123.514 125.018 156.370 1.00 68.70  ? 202 6PL D C31 1 
HETATM 7698 C C32 . 6PL L 3 .   ? 122.752 125.394 155.075 1.00 68.70  ? 202 6PL D C32 1 
HETATM 7699 C C33 . 6PL L 3 .   ? 123.576 124.954 153.836 1.00 68.70  ? 202 6PL D C33 1 
HETATM 7700 C C34 . 6PL L 3 .   ? 122.626 124.719 152.625 1.00 68.70  ? 202 6PL D C34 1 
HETATM 7701 C C35 . 6PL L 3 .   ? 123.460 124.263 151.402 1.00 68.70  ? 202 6PL D C35 1 
HETATM 7702 C C36 . 6PL L 3 .   ? 122.584 123.367 150.487 1.00 68.70  ? 202 6PL D C36 1 
HETATM 7703 C C37 . 6PL L 3 .   ? 122.636 123.891 149.027 1.00 68.70  ? 202 6PL D C37 1 
HETATM 7704 C C38 . 6PL L 3 .   ? 121.529 123.191 148.184 1.00 68.70  ? 202 6PL D C38 1 
HETATM 7705 C C39 . 6PL L 3 .   ? 121.110 124.110 147.013 1.00 68.70  ? 202 6PL D C39 1 
HETATM 7706 C C40 . 6PL L 3 .   ? 120.119 123.352 146.095 1.00 68.70  ? 202 6PL D C40 1 
HETATM 7707 C C41 . 6PL L 3 .   ? 119.578 124.312 144.996 1.00 68.70  ? 202 6PL D C41 1 
HETATM 7708 C C42 . 6PL L 3 .   ? 120.536 124.318 143.769 1.00 68.70  ? 202 6PL D C42 1 
HETATM 7709 C C43 . 6PL L 3 .   ? 119.904 125.133 142.621 1.00 68.70  ? 202 6PL D C43 1 
HETATM 7710 C C44 . 6PL L 3 .   ? 121.014 125.717 141.724 1.00 68.70  ? 202 6PL D C44 1 
HETATM 7711 C C45 . 6PL L 3 .   ? 120.777 127.226 141.518 1.00 68.70  ? 202 6PL D C45 1 
HETATM 7712 C C46 . 6PL L 3 .   ? 122.117 127.945 141.285 1.00 68.70  ? 202 6PL D C46 1 
HETATM 7713 C C47 . 6PL L 3 .   ? 121.942 129.464 141.446 1.00 68.70  ? 202 6PL D C47 1 
HETATM 7714 C C48 . 6PL L 3 .   ? 121.293 130.043 140.188 1.00 68.70  ? 202 6PL D C48 1 
# 
